Structure summary for 1G6V

Detailed entry information.

Key:

Heavy Chains
Light Chains
Bound Antigen Chains
Chothia CDRs
Other

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Complex Of The Camelid Heavy-Chain Antibody Fragment Cab-Ca05 With Bovine Carbonic Anhydrase

ItemInfo
PDB code: 1g6v
Organism: CAMELUS DROMEDARIUS
Experimental method: X-RAY DIFFRACTION
In complex: True
Fvs present: 1
Binding affinity (KD): 7.2e-08 M
ΔG: -9.74 kcal/mol
Affinity method: SPR
Source: Paper Link
Light chain type: NA
PDB has constant region: False

This PDB has 1 antibody variable fragment(s)

Fab Details:
ItemInfo
Heavy Chain K
Light Chain -
Heavy V / J subgroups IGHV1 / IGHJ4
Light subgroup
Bound-state Bound
Species CAMELUS DROMEDARIUS
ScFv? False
Constant domains present? False
Antigen Details:
ItemInfo
Chain A
Type protein
Name carbonic anhydrase
Species BOS TAURUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH K Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
QVQLVESGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
SVQAGGSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGYTVS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
TYCMGWFRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKEREGVAT
H51 H53 H54 H55 H56 H57 H58 H59 H60 H61
ILGGSTYYGD
H62 H63 H64 H65 H66 H67 H68 H69 H70 H71
SVKGRFTISQ
H72 H73 H74 H75 H76 H77 H78 H79 H80 H81
DNAKNTVYLQ
H82 H82AH82BH82CH83 H84 H85 H86 H87 H88
MNSLKPEDTA
H89 H90 H91 H92 H93 H94 H95 H96 H97 H98
IYYCAGSTVA
H99 H100 H100AH100BH100CH100DH100EH100FH100GH100H
STGWCSRLRP
H100IH100JH100KH101 H102 H103 H104 H105 H106 H107
YDYHYRGQGT
H108 H109 H110 H111 H112 H113
QVTVSS
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein A Download
M S H H W G Y G K H N G P E H W H K D F P I A K G E R Q S P
V D I D T H T A K Y D P S L K P L S V S Y D Q A T S L R I L
N N G H A F N V E F D D S Q D K A V L K G G P L D G T Y R L
I Q F H F H W G S L D G Q G S E H T V D K K K Y A A E L H L
V H W N T K Y G D F G K A V Q Q P D G L A V L G I F L K V G
S A K P G L Q K V V D V L D S I K T K G K S A D F T N F D P
R G L L P E S L D Y W T Y P G S L T T P P L L E C V T W I V
L K E P I S V S S E Q V L K F R K L N F N G E G E P E E L M
V D N W R P A Q P L K N R Q I K A S F K

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
K/-Get AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRH1 GYTVSTY
CDRH2 LGGS
CDRH3 STVASTGWCSRLRPYDYHY

Downloads and links.

ItemDownload link
Full structureDownload
Chothia structureDownload
Summary fileDownload
Entry in the PDBSee the file on the PDB
Entry in IMGTSee the IMGT entry
Flag misannotation