Structure summary for 3NGB

Chain type

Chain id

Fasta sequence

Chothia annotated sequence ( framework / CDRs )

VH

B

H1	H2	H3	H4	H5	H6	H7	H8	H9	H10
Q	V	Q	L	V	Q	S	G	G	Q

H11	H12	H13	H14	H15	H16	H17	H18	H19	H20
M	K	K	P	G	E	S	M	R	I

H21	H22	H23	H24	H25	H26	H27	H28	H29	H30
S	C	R	A	S	G	Y	E	F	I

H31	H32	H33	H34	H35	H36	H37	H38	H39	H40
D	C	T	L	N	W	I	R	L	A

H41	H42	H43	H44	H45	H46	H47	H48	H49	H50
P	G	K	R	P	E	W	M	G	W

H51	H52	H52A	H53	H54	H55	H56	H57	H58	H59
L	K	P	R	G	G	A	V	N	Y

H60	H61	H62	H63	H64	H65	H66	H67	H68	H69
A	R	P	L	Q	G	R	V	T	M

H70	H71	H72	H73	H74	H75	H76	H77	H78	H79
T	R	D	V	Y	S	D	T	A	F

H80	H81	H82	H82A	H82B	H82C	H83	H84	H85	H86
L	E	L	R	S	L	T	V	D	D

H87	H88	H89	H90	H91	H92	H93	H94	H95	H96
T	A	V	Y	F	C	T	R	G	K

H97	H98	H99	H100	H100A	H100B	H100C	H100D	H101	H102
N	C	D	Y	N	W	D	F	E	H

H103	H104	H105	H106	H107	H108	H109	H110	H111	H112
W	G	R	G	T	P	V	I	V	S

H113
S

VL

C

L1	L2	L3	L4	L5	L6	L7	L8	L9	L10
E	I	V	L	T	Q	S	P	G	T

L11	L12	L13	L14	L15	L16	L17	L18	L19	L20
L	S	L	S	P	G	E	T	A	I

L21	L22	L23	L24	L25	L26	L27	L28	L29	L30
I	S	C	R	T	S	Q	Y	G	S

L33	L34	L35	L36	L37	L38	L39	L40	L41	L42
L	A	W	Y	Q	Q	R	P	G	Q

L43	L44	L45	L46	L47	L48	L49	L50	L51	L52
A	P	R	L	V	I	Y	S	G	S

L53	L54	L55	L56	L57	L58	L59	L60	L61	L62
T	R	A	A	G	I	P	D	R	F

L63	L64	L65	L66	L67	L68	L69	L70	L71	L72
S	G	S	R	W	G	P	D	Y	N

L73	L74	L75	L76	L77	L78	L79	L80	L81	L82
L	T	I	S	N	L	E	S	G	D

L83	L84	L85	L86	L87	L88	L89	L90	L91	L96
F	G	V	Y	Y	C	Q	Q	Y	E

L97	L98	L99	L100	L101	L102	L103	L104	L105	L106
F	F	G	Q	G	T	K	V	Q	V

L107	L108	L109	L110
D	I	K	R

Antigen type	Chain id	Fasta sequence	Sequence (Clustal colouring)
protein	A	Download	V W K D A D T T L F C A S D A K A H E T E V H N V W A T H A C V P T D P N P Q E I H L E N V T E N F N M W K N N M V E Q M Q E D V I S L W D Q S L Q P C V K L T G G S V I K Q A C P K I S F D P I P I H Y C T P A G Y V I L K C N D K N F N G T G P C K N V S S V Q C T H G I K P V V S T Q L L L N G S L A E E E I I I R S E N L T N N A K T I I V H L N K S V E I N C T R P S N G G S G S G G D I R K A Y C E I N G T K W N K V L K Q V T E K L K E H F N N K T I I F Q P P S G G D L E I T M H H F N C R G E F F Y C N T T Q L F N N T C I G N E T M K G C N G T I T L P C K I K Q I I N M W Q G T G Q A M Y A P P I D G K I N C V S N I T G I L L T R D G G A N N T S N E T F R P G G G N I K D N W R S E L Y K Y K V V Q I E

Antibody i-Patch annotation:

Fab heavy/lightchain	Link to the Antibody i-Patch annotation (What is this?)
B/C	Get AB i-Patch annotation

Chothia CDR information:

CDR	Sequence
CDRL1	RTSQYGSLA
CDRL2	SGSTRAA
CDRL3	QQYEF
CDRH1	GYEFIDC
CDRH2	KPRGGA
CDRH3	GKNCDYNWDFEH

VH-VL orientation:
(see plot)

Angle	Value
HL	-58.5°
HC1	76.4°
HC2	113.8°
LC1	126.5°
LC2	82.5°
dc	15.4 Å

E / F

Fab Details:

Item	Info
Heavy Chain	E
Light Chain	F
Heavy V / J / C subgroups	IGHV1 / IGHJ2 / IGHG1
Light V / J / C subgroups	IGKV3 / IGKJ1 / IGKC
Bound-state	Bound
Species	HOMO SAPIENS
ScFv?	False
Constant domains present?	True

Antigen Details:

Item	Info
Chain	D
Type	protein
Name	envelope glycoprotein gp160
Species	HUMAN IMMUNODEFICIENCY VIRUS 1

Sequence:

Chain type

Chain id

Fasta sequence

Chothia annotated sequence ( framework / CDRs )

VH

E

H1	H2	H3	H4	H5	H6	H7	H8	H9	H10
Q	V	Q	L	V	Q	S	G	G	Q

H11	H12	H13	H14	H15	H16	H17	H18	H19	H20
M	K	K	P	G	E	S	M	R	I

H21	H22	H23	H24	H25	H26	H27	H28	H29	H30
S	C	R	A	S	G	Y	E	F	I

H31	H32	H33	H34	H35	H36	H37	H38	H39	H40
D	C	T	L	N	W	I	R	L	A

H41	H42	H43	H44	H45	H46	H47	H48	H49	H50
P	G	K	R	P	E	W	M	G	W

H51	H52	H52A	H53	H54	H55	H56	H57	H58	H59
L	K	P	R	G	G	A	V	N	Y

H60	H61	H62	H63	H64	H65	H66	H67	H68	H69
A	R	P	L	Q	G	R	V	T	M

H70	H71	H72	H73	H74	H75	H76	H77	H78	H79
T	R	D	V	Y	S	D	T	A	F

H80	H81	H82	H82A	H82B	H82C	H83	H84	H85	H86
L	E	L	R	S	L	T	V	D	D

H87	H88	H89	H90	H91	H92	H93	H94	H95	H96
T	A	V	Y	F	C	T	R	G	K

H97	H98	H99	H100	H100A	H100B	H100C	H100D	H101	H102
N	C	D	Y	N	W	D	F	E	H

H103	H104	H105	H106	H107	H108	H109	H110	H111	H112
W	G	R	G	T	P	V	I	V	S

H113
S

VL

F

L1	L2	L3	L4	L5	L6	L7	L8	L9	L10
E	I	V	L	T	Q	S	P	G	T

L11	L12	L13	L14	L15	L16	L17	L18	L19	L20
L	S	L	S	P	G	E	T	A	I

L21	L22	L23	L24	L25	L26	L27	L28	L29	L30
I	S	C	R	T	S	Q	Y	G	S

L33	L34	L35	L36	L37	L38	L39	L40	L41	L42
L	A	W	Y	Q	Q	R	P	G	Q

L43	L44	L45	L46	L47	L48	L49	L50	L51	L52
A	P	R	L	V	I	Y	S	G	S

L53	L54	L55	L56	L57	L58	L59	L60	L61	L62
T	R	A	A	G	I	P	D	R	F

L63	L64	L65	L66	L67	L68	L69	L70	L71	L72
S	G	S	R	W	G	P	D	Y	N

L73	L74	L75	L76	L77	L78	L79	L80	L81	L82
L	T	I	S	N	L	E	S	G	D

L83	L84	L85	L86	L87	L88	L89	L90	L91	L96
F	G	V	Y	Y	C	Q	Q	Y	E

L97	L98	L99	L100	L101	L102	L103	L104	L105	L106
F	F	G	Q	G	T	K	V	Q	V

L107	L108	L109	L110
D	I	K	R

Antigen type	Chain id	Fasta sequence	Sequence (Clustal colouring)
protein	D	Download	V W K D A D T T L F C A S D A K A H E T E V H N V W A T H A C V P T D P N P Q E I H L E N V T E N F N M W K N N M V E Q M Q E D V I S L W D Q S L Q P C V K L T G G S V I K Q A C P K I S F D P I P I H Y C T P A G Y V I L K C N D K N F N G T G P C K N V S S V Q C T H G I K P V V S T Q L L L N G S L A E E E I I I R S E N L T N N A K T I I V H L N K S V E I N C T R P S N G G S G S G G D I R K A Y C E I N G T K W N K V L K Q V T E K L K E H F N N K T I I F Q P P S G G D L E I T M H H F N C R G E F F Y C N T T Q L F N N T C I G N E T M K G C N G T I T L P C K I K Q I I N M W Q G T G Q A M Y A P P I D G K I N C V S N I T G I L L T R D G G A N N T S N E T F R P G G G N I K D N W R S E L Y K Y K V V Q I E

Antibody i-Patch annotation:

Fab heavy/lightchain	Link to the Antibody i-Patch annotation (What is this?)
E/F	Get AB i-Patch annotation

Chothia CDR information:

CDR	Sequence
CDRL1	RTSQYGSLA
CDRL2	SGSTRAA
CDRL3	QQYEF
CDRH1	GYEFIDC
CDRH2	KPRGGA
CDRH3	GKNCDYNWDFEH

VH-VL orientation:
(see plot)

Angle	Value
HL	-58.2°
HC1	77.1°
HC2	114.5°
LC1	126.2°
LC2	82.5°
dc	15.3 Å

H / L

Fab Details:

Item	Info
Heavy Chain	H
Light Chain	L
Heavy V / J / C subgroups	IGHV1 / IGHJ2 / IGHG1
Light V / J / C subgroups	IGKV3 / IGKJ1 / IGKC
Bound-state	Bound
Species	HOMO SAPIENS
ScFv?	False
Constant domains present?	True

Antigen Details:

Item	Info
Chain	G
Type	protein
Name	envelope glycoprotein gp160
Species	HUMAN IMMUNODEFICIENCY VIRUS 1

Sequence:

Chain type

Chain id

Fasta sequence

Chothia annotated sequence ( framework / CDRs )

VH

H

H1	H2	H3	H4	H5	H6	H7	H8	H9	H10
Q	V	Q	L	V	Q	S	G	G	Q

H11	H12	H13	H14	H15	H16	H17	H18	H19	H20
M	K	K	P	G	E	S	M	R	I

H21	H22	H23	H24	H25	H26	H27	H28	H29	H30
S	C	R	A	S	G	Y	E	F	I

H31	H32	H33	H34	H35	H36	H37	H38	H39	H40
D	C	T	L	N	W	I	R	L	A

H41	H42	H43	H44	H45	H46	H47	H48	H49	H50
P	G	K	R	P	E	W	M	G	W

H51	H52	H52A	H53	H54	H55	H56	H57	H58	H59
L	K	P	R	G	G	A	V	N	Y

H60	H61	H62	H63	H64	H65	H66	H67	H68	H69
A	R	P	L	Q	G	R	V	T	M

H70	H71	H72	H73	H74	H75	H76	H77	H78	H79
T	R	D	V	Y	S	D	T	A	F

H80	H81	H82	H82A	H82B	H82C	H83	H84	H85	H86
L	E	L	R	S	L	T	V	D	D

H87	H88	H89	H90	H91	H92	H93	H94	H95	H96
T	A	V	Y	F	C	T	R	G	K

H97	H98	H99	H100	H100A	H100B	H100C	H100D	H101	H102
N	C	D	Y	N	W	D	F	E	H

H103	H104	H105	H106	H107	H108	H109	H110	H111	H112
W	G	R	G	T	P	V	I	V	S

H113
S

VL

L

L1	L2	L3	L4	L5	L6	L7	L8	L9	L10
E	I	V	L	T	Q	S	P	G	T

L11	L12	L13	L14	L15	L16	L17	L18	L19	L20
L	S	L	S	P	G	E	T	A	I

L21	L22	L23	L24	L25	L26	L27	L28	L29	L30
I	S	C	R	T	S	Q	Y	G	S

L33	L34	L35	L36	L37	L38	L39	L40	L41	L42
L	A	W	Y	Q	Q	R	P	G	Q

L43	L44	L45	L46	L47	L48	L49	L50	L51	L52
A	P	R	L	V	I	Y	S	G	S

L53	L54	L55	L56	L57	L58	L59	L60	L61	L62
T	R	A	A	G	I	P	D	R	F

L63	L64	L65	L66	L67	L68	L69	L70	L71	L72
S	G	S	R	W	G	P	D	Y	N

L73	L74	L75	L76	L77	L78	L79	L80	L81	L82
L	T	I	S	N	L	E	S	G	D

L83	L84	L85	L86	L87	L88	L89	L90	L91	L96
F	G	V	Y	Y	C	Q	Q	Y	E

L97	L98	L99	L100	L101	L102	L103	L104	L105	L106
F	F	G	Q	G	T	K	V	Q	V

L107	L108	L109	L110
D	I	K	R

Antigen type	Chain id	Fasta sequence	Sequence (Clustal colouring)
protein	G	Download	V W K D A D T T L F C A S D A K A H E T E V H N V W A T H A C V P T D P N P Q E I H L E N V T E N F N M W K N N M V E Q M Q E D V I S L W D Q S L Q P C V K L T G G S V I K Q A C P K I S F D P I P I H Y C T P A G Y V I L K C N D K N F N G T G P C K N V S S V Q C T H G I K P V V S T Q L L L N G S L A E E E I I I R S E N L T N N A K T I I V H L N K S V E I N C T R P S N G G S G S G G D I R K A Y C E I N G T K W N K V L K Q V T E K L K E H F N N K T I I F Q P P S G G D L E I T M H H F N C R G E F F Y C N T T Q L F N N T C I G N E T M K G C N G T I T L P C K I K Q I I N M W Q G T G Q A M Y A P P I D G K I N C V S N I T G I L L T R D G G A N N T S N E T F R P G G G N I K D N W R S E L Y K Y K V V Q I E

Antibody i-Patch annotation:

Fab heavy/lightchain	Link to the Antibody i-Patch annotation (What is this?)
H/L	Get AB i-Patch annotation

Chothia CDR information:

CDR	Sequence
CDRL1	RTSQYGSLA
CDRL2	SGSTRAA
CDRL3	QQYEF
CDRH1	GYEFIDC
CDRH2	KPRGGA
CDRH3	GKNCDYNWDFEH

VH-VL orientation:
(see plot)

Angle	Value
HL	-57.8°
HC1	76.9°
HC2	114.9°
LC1	126.8°
LC2	82.1°
dc	15.4 Å

J / K

Fab Details:

Item	Info
Heavy Chain	J
Light Chain	K
Heavy V / J / C subgroups	IGHV1 / IGHJ2 / IGHG1
Light V / J / C subgroups	IGKV3 / IGKJ1 / IGKC
Bound-state	Bound
Species	HOMO SAPIENS
ScFv?	False
Constant domains present?	True

Antigen Details:

Item	Info
Chain	I
Type	protein
Name	envelope glycoprotein gp160
Species	HUMAN IMMUNODEFICIENCY VIRUS 1

Sequence:

Chain type

Chain id

Fasta sequence

Chothia annotated sequence ( framework / CDRs )

VH

J

H1	H2	H3	H4	H5	H6	H7	H8	H9	H10
Q	V	Q	L	V	Q	S	G	G	Q

H11	H12	H13	H14	H15	H16	H17	H18	H19	H20
M	K	K	P	G	E	S	M	R	I

H21	H22	H23	H24	H25	H26	H27	H28	H29	H30
S	C	R	A	S	G	Y	E	F	I

H31	H32	H33	H34	H35	H36	H37	H38	H39	H40
D	C	T	L	N	W	I	R	L	A

H41	H42	H43	H44	H45	H46	H47	H48	H49	H50
P	G	K	R	P	E	W	M	G	W

H51	H52	H52A	H53	H54	H55	H56	H57	H58	H59
L	K	P	R	G	G	A	V	N	Y

H60	H61	H62	H63	H64	H65	H66	H67	H68	H69
A	R	P	L	Q	G	R	V	T	M

H70	H71	H72	H73	H74	H75	H76	H77	H78	H79
T	R	D	V	Y	S	D	T	A	F

H80	H81	H82	H82A	H82B	H82C	H83	H84	H85	H86
L	E	L	R	S	L	T	V	D	D

H87	H88	H89	H90	H91	H92	H93	H94	H95	H96
T	A	V	Y	F	C	T	R	G	K

H97	H98	H99	H100	H100A	H100B	H100C	H100D	H101	H102
N	C	D	Y	N	W	D	F	E	H

H103	H104	H105	H106	H107	H108	H109	H110	H111	H112
W	G	R	G	T	P	V	I	V	S

H113
S

VL

K

L1	L2	L3	L4	L5	L6	L7	L8	L9	L10
E	I	V	L	T	Q	S	P	G	T

L11	L12	L13	L14	L15	L16	L17	L18	L19	L20
L	S	L	S	P	G	E	T	A	I

L21	L22	L23	L24	L25	L26	L27	L28	L29	L30
I	S	C	R	T	S	Q	Y	G	S

L33	L34	L35	L36	L37	L38	L39	L40	L41	L42
L	A	W	Y	Q	Q	R	P	G	Q

L43	L44	L45	L46	L47	L48	L49	L50	L51	L52
A	P	R	L	V	I	Y	S	G	S

L53	L54	L55	L56	L57	L58	L59	L60	L61	L62
T	R	A	A	G	I	P	D	R	F

L63	L64	L65	L66	L67	L68	L69	L70	L71	L72
S	G	S	R	W	G	P	D	Y	N

L73	L74	L75	L76	L77	L78	L79	L80	L81	L82
L	T	I	S	N	L	E	S	G	D

L83	L84	L85	L86	L87	L88	L89	L90	L91	L96
F	G	V	Y	Y	C	Q	Q	Y	E

L97	L98	L99	L100	L101	L102	L103	L104	L105	L106
F	F	G	Q	G	T	K	V	Q	V

L107	L108	L109	L110
D	I	K	R