Structure summary for 4GXU

Detailed entry information.

Key:

Heavy Chains
Light Chains
Bound Antigen Chains
Chothia CDRs
Other

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Crystal Structure Of Antibody 1F1 Bound To The 1918 Influenza Hemagglutinin

ItemInfo
PDB code: 4gxu
Organism: HOMO SAPIENS
Experimental method: X-RAY DIFFRACTION
In complex: True
Fvs present: 6
Binding affinity (KD): 6.24e-09 M
ΔG: None kcal/mol
Affinity method: SPR
Source: Paper Link
Light chain type: Lambda
PDB has constant region: True

This PDB has 6 antibody variable fragment(s)

Fab Details:
ItemInfo
Heavy Chain M
Light Chain N
Heavy V subgroup IGHV3 *
Light V subgroup IGLV1 *
Bound-state Bound
Species HOMO SAPIENS
ScFv? False
Constant domains present? True
Antigen Details:
ItemInfo
Chain A
Type protein
Name hemagglutinin ha1 chain
Species INFLUENZA A VIRUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH M Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
EVQLVQSGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
VVQPRRSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGFTFS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
SYAMHWVRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKGLEWVAV
H51 H52 H52AH53 H54 H55 H56 H57 H58 H59
ISYDGRNKYY
H60 H61 H62 H63 H64 H65 H66 H67 H68 H69
ADSVKGRFTV
H70 H71 H72 H73 H74 H75 H76 H77 H78 H79
SRDNSKNTLY
H80 H81 H82 H82AH82BH82CH83 H84 H85 H86
LQMNSLRAED
H87 H88 H89 H90 H91 H92 H93 H94 H95 H96
TSVYYCAREL
H97 H98 H99 H100 H100AH100BH100CH100DH100EH100F
LMDYYDHIGY
H100GH100HH100IH101 H102 H103 H104 H105 H106 H107
SPGPTWGQGT
H108 H109 H110 H111 H112 H113
LVTVSS
VL N Download
L1 L2 L3 L4 L5 L6 L7 L8 L9 L11
EPVLTQPPSA
L12 L13 L14 L15 L16 L17 L18 L19 L20 L21
SGSPGQRVTI
L22 L23 L24 L25 L26 L27 L28 L29 L30 L30A
SCSGSSSNIG
L30BL31 L32 L33 L34 L35 L36 L37 L38 L39
SYTVNWYQQL
L40 L41 L42 L43 L44 L45 L46 L47 L48 L49
PGTAPKLLIY
L50 L51 L52 L53 L54 L55 L56 L57 L58 L59
SLNQRPSGVP
L60 L61 L62 L63 L64 L65 L66 L67 L68 L69
DRFSGSKSGT
L70 L71 L72 L73 L74 L75 L76 L77 L78 L79
SASLAISGLQ
L80 L81 L82 L83 L84 L85 L86 L87 L88 L89
SEDEAVYYCA
L90 L91 L92 L93 L94 L95 L95AL95BL95CL96
AWDDSLSAHV
L97 L98 L99 L100 L101 L102 L103 L104 L105 L106
VFGGGTKLTV
L106AL107 L108 L109
LGQP
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein A Download
A D P G D T I C I G Y H A N N S T D T V D T V L E K N V T V
T H S V N L L E D S H N G K L C K L K G I A P L Q L G K C N
I A G W L L G N P E C D L L L T A S S W S Y I V E T S N S E
N G T C Y P G D F I D Y E E L R E Q L S S V S S F E K F E I
F P K T S S W P N H E T T K G V T A A C S Y A G A S S F Y R
N L L W L T K K G S S Y P K L S K S Y V N N K G K E V L V L
W G V H H P P T G T D Q Q S L Y Q N A D A Y V S V G S S K Y
N R R F T P E I A A R P K V R D Q A G R M N Y Y W T L L E P
G D T I T F E A T G N L I A P W Y A F A L N R G S G S G I I
T S D A P V H D C N T K C Q T P H G A I N S S L P F Q N I H
P V T I G E C P K Y V R S T K L R M A T G L R N I P S I Q S
R

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
M/NGet AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRL1 SGSSSNIGSYTVN
CDRL2 SLNQRPS
CDRL3 AAWDDSLSAHVV
CDRH1 GFTFSSY
CDRH2 SYDGRN
CDRH3 ELLMDYYDHIGYSPGPT
VH-VL orientation:
(see plot)
AngleValue
HL -58.4°
HC1 71.1°
HC2 121.3°
LC1 118.7°
LC2 83.0°
dc 16.0 Å
Fab Details:
ItemInfo
Heavy Chain O
Light Chain P
Heavy V subgroup IGHV3 *
Light V subgroup IGLV1 *
Bound-state Bound
Species HOMO SAPIENS
ScFv? False
Constant domains present? True
Antigen Details:
ItemInfo
Chain C
Type protein
Name hemagglutinin ha1 chain
Species INFLUENZA A VIRUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH O Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
EVQLVQSGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
VVQPRRSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGFTFS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
SYAMHWVRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKGLEWVAV
H51 H52 H52AH53 H54 H55 H56 H57 H58 H59
ISYDGRNKYY
H60 H61 H62 H63 H64 H65 H66 H67 H68 H69
ADSVKGRFTV
H70 H71 H72 H73 H74 H75 H76 H77 H78 H79
SRDNSKNTLY
H80 H81 H82 H82AH82BH82CH83 H84 H85 H86
LQMNSLRAED
H87 H88 H89 H90 H91 H92 H93 H94 H95 H96
TSVYYCAREL
H97 H98 H99 H100 H100AH100BH100CH100DH100EH100F
LMDYYDHIGY
H100GH100HH100IH101 H102 H103 H104 H105 H106 H107
SPGPTWGQGT
H108 H109 H110 H111 H112 H113
LVTVSS
VL P Download
L1 L2 L3 L4 L5 L6 L7 L8 L9 L11
EPVLTQPPSA
L12 L13 L14 L15 L16 L17 L18 L19 L20 L21
SGSPGQRVTI
L22 L23 L24 L25 L26 L27 L28 L29 L30 L30A
SCSGSSSNIG
L30BL31 L32 L33 L34 L35 L36 L37 L38 L39
SYTVNWYQQL
L40 L41 L42 L43 L44 L45 L46 L47 L48 L49
PGTAPKLLIY
L50 L51 L52 L53 L54 L55 L56 L57 L58 L59
SLNQRPSGVP
L60 L61 L62 L63 L64 L65 L66 L67 L68 L69
DRFSGSKSGT
L70 L71 L72 L73 L74 L75 L76 L77 L78 L79
SASLAISGLQ
L80 L81 L82 L83 L84 L85 L86 L87 L88 L89
SEDEAVYYCA
L90 L91 L92 L93 L94 L95 L95AL95BL95CL96
AWDDSLSAHV
L97 L98 L99 L100 L101 L102 L103 L104 L105 L106
VFGGGTKLTV
L106AL107 L108 L109
LGQP
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein C Download
A D P G D T I C I G Y H A N N S T D T V D T V L E K N V T V
T H S V N L L E D S H N G K L C K L K G I A P L Q L G K C N
I A G W L L G N P E C D L L L T A S S W S Y I V E T S N S E
N G T C Y P G D F I D Y E E L R E Q L S S V S S F E K F E I
F P K T S S W P N H E T T K G V T A A C S Y A G A S S F Y R
N L L W L T K K G S S Y P K L S K S Y V N N K G K E V L V L
W G V H H P P T G T D Q Q S L Y Q N A D A Y V S V G S S K Y
N R R F T P E I A A R P K V R D Q A G R M N Y Y W T L L E P
G D T I T F E A T G N L I A P W Y A F A L N R G S G S G I I
T S D A P V H D C N T K C Q T P H G A I N S S L P F Q N I H
P V T I G E C P K Y V R S T K L R M A T G L R N I P S I Q S
R

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
O/PGet AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRL1 SGSSSNIGSYTVN
CDRL2 SLNQRPS
CDRL3 AAWDDSLSAHVV
CDRH1 GFTFSSY
CDRH2 SYDGRN
CDRH3 ELLMDYYDHIGYSPGPT
VH-VL orientation:
(see plot)
AngleValue
HL -57.4°
HC1 70.6°
HC2 121.9°
LC1 116.5°
LC2 83.7°
dc 16.2 Å
Fab Details:
ItemInfo
Heavy Chain Q
Light Chain R
Heavy V subgroup IGHV3 *
Light V subgroup IGLV1 *
Bound-state Bound
Species HOMO SAPIENS
ScFv? False
Constant domains present? True
Antigen Details:
ItemInfo
Chain E
Type protein
Name hemagglutinin ha1 chain
Species INFLUENZA A VIRUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH Q Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
EVQLVQSGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
VVQPRRSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGFTFS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
SYAMHWVRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKGLEWVAV
H51 H52 H52AH53 H54 H55 H56 H57 H58 H59
ISYDGRNKYY
H60 H61 H62 H63 H64 H65 H66 H67 H68 H69
ADSVKGRFTV
H70 H71 H72 H73 H74 H75 H76 H77 H78 H79
SRDNSKNTLY
H80 H81 H82 H82AH82BH82CH83 H84 H85 H86
LQMNSLRAED
H87 H88 H89 H90 H91 H92 H93 H94 H95 H96
TSVYYCAREL
H97 H98 H99 H100 H100AH100BH100CH100DH100EH100F
LMDYYDHIGY
H100GH100HH100IH101 H102 H103 H104 H105 H106 H107
SPGPTWGQGT
H108 H109 H110 H111 H112 H113
LVTVSS
VL R Download
L1 L2 L3 L4 L5 L6 L7 L8 L9 L11
EPVLTQPPSA
L12 L13 L14 L15 L16 L17 L18 L19 L20 L21
SGSPGQRVTI
L22 L23 L24 L25 L26 L27 L28 L29 L30 L30A
SCSGSSSNIG
L30BL31 L32 L33 L34 L35 L36 L37 L38 L39
SYTVNWYQQL
L40 L41 L42 L43 L44 L45 L46 L47 L48 L49
PGTAPKLLIY
L50 L51 L52 L53 L54 L55 L56 L57 L58 L59
SLNQRPSGVP
L60 L61 L62 L63 L64 L65 L66 L67 L68 L69
DRFSGSKSGT
L70 L71 L72 L73 L74 L75 L76 L77 L78 L79
SASLAISGLQ
L80 L81 L82 L83 L84 L85 L86 L87 L88 L89
SEDEAVYYCA
L90 L91 L92 L93 L94 L95 L95AL95BL95CL96
AWDDSLSAHV
L97 L98 L99 L100 L101 L102 L103 L104 L105 L106
VFGGGTKLTV
L106AL107 L108 L109
LGQP
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein E Download
A D P G D T I C I G Y H A N N S T D T V D T V L E K N V T V
T H S V N L L E D S H N G K L C K L K G I A P L Q L G K C N
I A G W L L G N P E C D L L L T A S S W S Y I V E T S N S E
N G T C Y P G D F I D Y E E L R E Q L S S V S S F E K F E I
F P K T S S W P N H E T T K G V T A A C S Y A G A S S F Y R
N L L W L T K K G S S Y P K L S K S Y V N N K G K E V L V L
W G V H H P P T G T D Q Q S L Y Q N A D A Y V S V G S S K Y
N R R F T P E I A A R P K V R D Q A G R M N Y Y W T L L E P
G D T I T F E A T G N L I A P W Y A F A L N R G S G S G I I
T S D A P V H D C N T K C Q T P H G A I N S S L P F Q N I H
P V T I G E C P K Y V R S T K L R M A T G L R N I P S I Q S
R

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
Q/RGet AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRL1 SGSSSNIGSYTVN
CDRL2 SLNQRPS
CDRL3 AAWDDSLSAHVV
CDRH1 GFTFSSY
CDRH2 SYDGRN
CDRH3 ELLMDYYDHIGYSPGPT
VH-VL orientation:
(see plot)
AngleValue
HL -57.6°
HC1 70.8°
HC2 121.7°
LC1 119.3°
LC2 83.7°
dc 16.0 Å
Fab Details:
ItemInfo
Heavy Chain S
Light Chain T
Heavy V subgroup IGHV3 *
Light V subgroup IGLV1 *
Bound-state Bound
Species HOMO SAPIENS
ScFv? False
Constant domains present? True
Antigen Details:
ItemInfo
Chain G
Type protein
Name hemagglutinin ha1 chain
Species INFLUENZA A VIRUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH S Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
EVQLVQSGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
VVQPRRSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGFTFS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
SYAMHWVRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKGLEWVAV
H51 H52 H52AH53 H54 H55 H56 H57 H58 H59
ISYDGRNKYY
H60 H61 H62 H63 H64 H65 H66 H67 H68 H69
ADSVKGRFTV
H70 H71 H72 H73 H74 H75 H76 H77 H78 H79
SRDNSKNTLY
H80 H81 H82 H82AH82BH82CH83 H84 H85 H86
LQMNSLRAED
H87 H88 H89 H90 H91 H92 H93 H94 H95 H96
TSVYYCAREL
H97 H98 H99 H100 H100AH100BH100CH100DH100EH100F
LMDYYDHIGY
H100GH100HH100IH101 H102 H103 H104 H105 H106 H107
SPGPTWGQGT
H108 H109 H110 H111 H112 H113
LVTVSS
VL T Download
L1 L2 L3 L4 L5 L6 L7 L8 L9 L11
EPVLTQPPSA
L12 L13 L14 L15 L16 L17 L18 L19 L20 L21
SGSPGQRVTI
L22 L23 L24 L25 L26 L27 L28 L29 L30 L30A
SCSGSSSNIG
L30BL31 L32 L33 L34 L35 L36 L37 L38 L39
SYTVNWYQQL
L40 L41 L42 L43 L44 L45 L46 L47 L48 L49
PGTAPKLLIY
L50 L51 L52 L53 L54 L55 L56 L57 L58 L59
SLNQRPSGVP
L60 L61 L62 L63 L64 L65 L66 L67 L68 L69
DRFSGSKSGT
L70 L71 L72 L73 L74 L75 L76 L77 L78 L79
SASLAISGLQ
L80 L81 L82 L83 L84 L85 L86 L87 L88 L89
SEDEAVYYCA
L90 L91 L92 L93 L94 L95 L95AL95BL95CL96
AWDDSLSAHV
L97 L98 L99 L100 L101 L102 L103 L104 L105 L106
VFGGGTKLTV
L106AL107 L108 L109
LGQP
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein G Download
A D P G D T I C I G Y H A N N S T D T V D T V L E K N V T V
T H S V N L L E D S H N G K L C K L K G I A P L Q L G K C N
I A G W L L G N P E C D L L L T A S S W S Y I V E T S N S E
N G T C Y P G D F I D Y E E L R E Q L S S V S S F E K F E I
F P K T S S W P N H E T T K G V T A A C S Y A G A S S F Y R
N L L W L T K K G S S Y P K L S K S Y V N N K G K E V L V L
W G V H H P P T G T D Q Q S L Y Q N A D A Y V S V G S S K Y
N R R F T P E I A A R P K V R D Q A G R M N Y Y W T L L E P
G D T I T F E A T G N L I A P W Y A F A L N R G S G S G I I
T S D A P V H D C N T K C Q T P H G A I N S S L P F Q N I H
P V T I G E C P K Y V R S T K L R M A T G L R N I P S I Q S
R

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
S/TGet AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRL1 SGSSSNIGSYTVN
CDRL2 SLNQRPS
CDRL3 AAWDDSLSAHVV
CDRH1 GFTFSSY
CDRH2 SYDGRN
CDRH3 ELLMDYYDHIGYSPGPT
VH-VL orientation:
(see plot)
AngleValue
HL -58.4°
HC1 70.8°
HC2 120.8°
LC1 116.7°
LC2 82.8°
dc 16.1 Å
Fab Details:
ItemInfo
Heavy Chain U
Light Chain V
Heavy V subgroup IGHV3 *
Light V subgroup IGLV1 *
Bound-state Bound
Species HOMO SAPIENS
ScFv? False
Constant domains present? True
Antigen Details:
ItemInfo
Chain I
Type protein
Name hemagglutinin ha1 chain
Species INFLUENZA A VIRUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH U Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
EVQLVQSGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
VVQPRRSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGFTFS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
SYAMHWVRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKGLEWVAV
H51 H52 H52AH53 H54 H55 H56 H57 H58 H59
ISYDGRNKYY
H60 H61 H62 H63 H64 H65 H66 H67 H68 H69
ADSVKGRFTV
H70 H71 H72 H73 H74 H75 H76 H77 H78 H79
SRDNSKNTLY
H80 H81 H82 H82AH82BH82CH83 H84 H85 H86
LQMNSLRAED
H87 H88 H89 H90 H91 H92 H93 H94 H95 H96
TSVYYCAREL
H97 H98 H99 H100 H100AH100BH100CH100DH100EH100F
LMDYYDHIGY
H100GH100HH100IH101 H102 H103 H104 H105 H106 H107
SPGPTWGQGT
H108 H109 H110 H111 H112 H113
LVTVSS
VL V Download
L1 L2 L3 L4 L5 L6 L7 L8 L9 L11
EPVLTQPPSA
L12 L13 L14 L15 L16 L17 L18 L19 L20 L21
SGSPGQRVTI
L22 L23 L24 L25 L26 L27 L28 L29 L30 L30A
SCSGSSSNIG
L30BL31 L32 L33 L34 L35 L36 L37 L38 L39
SYTVNWYQQL
L40 L41 L42 L43 L44 L45 L46 L47 L48 L49
PGTAPKLLIY
L50 L51 L52 L53 L54 L55 L56 L57 L58 L59
SLNQRPSGVP
L60 L61 L62 L63 L64 L65 L66 L67 L68 L69
DRFSGSKSGT
L70 L71 L72 L73 L74 L75 L76 L77 L78 L79
SASLAISGLQ
L80 L81 L82 L83 L84 L85 L86 L87 L88 L89
SEDEAVYYCA
L90 L91 L92 L93 L94 L95 L95AL95BL95CL96
AWDDSLSAHV
L97 L98 L99 L100 L101 L102 L103 L104 L105 L106
VFGGGTKLTV
L106AL107 L108 L109
LGQP
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein I Download
A D P G D T I C I G Y H A N N S T D T V D T V L E K N V T V
T H S V N L L E D S H N G K L C K L K G I A P L Q L G K C N
I A G W L L G N P E C D L L L T A S S W S Y I V E T S N S E
N G T C Y P G D F I D Y E E L R E Q L S S V S S F E K F E I
F P K T S S W P N H E T T K G V T A A C S Y A G A S S F Y R
N L L W L T K K G S S Y P K L S K S Y V N N K G K E V L V L
W G V H H P P T G T D Q Q S L Y Q N A D A Y V S V G S S K Y
N R R F T P E I A A R P K V R D Q A G R M N Y Y W T L L E P
G D T I T F E A T G N L I A P W Y A F A L N R G S G S G I I
T S D A P V H D C N T K C Q T P H G A I N S S L P F Q N I H
P V T I G E C P K Y V R S T K L R M A T G L R N I P S I Q S
R

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
U/VGet AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRL1 SGSSSNIGSYTVN
CDRL2 SLNQRPS
CDRL3 AAWDDSLSAHVV
CDRH1 GFTFSSY
CDRH2 SYDGRN
CDRH3 ELLMDYYDHIGYSPGPT
VH-VL orientation:
(see plot)
AngleValue
HL -57.6°
HC1 69.6°
HC2 121.1°
LC1 117.8°
LC2 82.8°
dc 16.1 Å
Fab Details:
ItemInfo
Heavy Chain W
Light Chain X
Heavy V subgroup IGHV3 *
Light V subgroup IGLV1 *
Bound-state Bound
Species HOMO SAPIENS
ScFv? False
Constant domains present? True
Antigen Details:
ItemInfo
Chain K
Type protein
Name hemagglutinin ha1 chain
Species INFLUENZA A VIRUS

Sequence:
Chain typeChain idFasta sequenceChothia annotated sequence ( framework / CDRs )
VH W Download
H1 H2 H3 H4 H5 H6 H7 H8 H9 H10
EVQLVQSGGG
H11 H12 H13 H14 H15 H16 H17 H18 H19 H20
VVQPRRSLRL
H21 H22 H23 H24 H25 H26 H27 H28 H29 H30
SCAASGFTFS
H31 H32 H33 H34 H35 H36 H37 H38 H39 H40
SYAMHWVRQA
H41 H42 H43 H44 H45 H46 H47 H48 H49 H50
PGKGLEWVAV
H51 H52 H52AH53 H54 H55 H56 H57 H58 H59
ISYDGRNKYY
H60 H61 H62 H63 H64 H65 H66 H67 H68 H69
ADSVKGRFTV
H70 H71 H72 H73 H74 H75 H76 H77 H78 H79
SRDNSKNTLY
H80 H81 H82 H82AH82BH82CH83 H84 H85 H86
LQMNSLRAED
H87 H88 H89 H90 H91 H92 H93 H94 H95 H96
TSVYYCAREL
H97 H98 H99 H100 H100AH100BH100CH100DH100EH100F
LMDYYDHIGY
H100GH100HH100IH101 H102 H103 H104 H105 H106 H107
SPGPTWGQGT
H108 H109 H110 H111 H112 H113
LVTVSS
VL X Download
L1 L2 L3 L4 L5 L6 L7 L8 L9 L11
EPVLTQPPSA
L12 L13 L14 L15 L16 L17 L18 L19 L20 L21
SGSPGQRVTI
L22 L23 L24 L25 L26 L27 L28 L29 L30 L30A
SCSGSSSNIG
L30BL31 L32 L33 L34 L35 L36 L37 L38 L39
SYTVNWYQQL
L40 L41 L42 L43 L44 L45 L46 L47 L48 L49
PGTAPKLLIY
L50 L51 L52 L53 L54 L55 L56 L57 L58 L59
SLNQRPSGVP
L60 L61 L62 L63 L64 L65 L66 L67 L68 L69
DRFSGSKSGT
L70 L71 L72 L73 L74 L75 L76 L77 L78 L79
SASLAISGLQ
L80 L81 L82 L83 L84 L85 L86 L87 L88 L89
SEDEAVYYCA
L90 L91 L92 L93 L94 L95 L95AL95BL95CL96
AWDDSLSAHV
L97 L98 L99 L100 L101 L102 L103 L104 L105 L106
VFGGGTKLTV
L106AL107 L108 L109
LGQP
Antigen typeChain idFasta sequenceSequence (Clustal colouring)
protein K Download
A D P G D T I C I G Y H A N N S T D T V D T V L E K N V T V
T H S V N L L E D S H N G K L C K L K G I A P L Q L G K C N
I A G W L L G N P E C D L L L T A S S W S Y I V E T S N S E
N G T C Y P G D F I D Y E E L R E Q L S S V S S F E K F E I
F P K T S S W P N H E T T K G V T A A C S Y A G A S S F Y R
N L L W L T K K G S S Y P K L S K S Y V N N K G K E V L V L
W G V H H P P T G T D Q Q S L Y Q N A D A Y V S V G S S K Y
N R R F T P E I A A R P K V R D Q A G R M N Y Y W T L L E P
G D T I T F E A T G N L I A P W Y A F A L N R G S G S G I I
T S D A P V H D C N T K C Q T P H G A I N S S L P F Q N I H
P V T I G E C P K Y V R S T K L R M A T G L R N I P S I Q S
R

Antibody i-Patch annotation:
Fab heavy/lightchainLink to the Antibody i-Patch annotation (What is this?)
W/XGet AB i-Patch annotation
Chothia CDR information:
CDRSequence
CDRL1 SGSSSNIGSYTVN
CDRL2 SLNQRPS
CDRL3 AAWDDSLSAHVV
CDRH1 GFTFSSY
CDRH2 SYDGRN
CDRH3 ELLMDYYDHIGYSPGPT
VH-VL orientation:
(see plot)
AngleValue
HL -59.6°
HC1 70.4°
HC2 120.8°
LC1 118.8°
LC2 82.2°
dc 16.0 Å

Downloads and links.

ItemDownload link
Full structureDownload
Chothia structureDownload
Summary fileDownload
Entry in the PDBSee the file on the PDB
Flag misannotation