About us

Alpha Helix kinks Assessed by Humans (AH^AH): a bioinformatics crowd-sourcing experiment making use of your puzzle solving skills.

AH^AH is a crowd-sourcing project carried out by the Oxford Protein Informatics Group (OPIG). The aim is to utilize human puzzle solving skills to coin a new gold standard on the definition of kinks in protein α helices. This is of special interest for our research because kinks play a fundamental role in cellular signal transduction and drug discovery. Further news and progress reports can be found at our group blog.

If you would like to know more about us, or have any questions contact us.

Jean-Paul Ebejer, Henry Wilman, Bernhard Knapp, Charlotte Deane