Memoir is a homology modelling algorithm designed for membrane proteins. The inputs are the sequence which is to be modelled, and the 3D structure of a template membrane protein. We have a short video tutorial on how to use Memoir and an example results page. We also have a tutorial on how to model multiple chain transmembrane proteins.

Memoir integrates our membrane protein software programs:

For more information on these, click the relevant program name.

You can populate the form below with example data.

If you use this web server please cite: Memoir: template-based structure prediction for membrane proteins. Jean-Paul Ebejer; Jamie R. Hill; Sebastian Kelm; Jiye Shi; Charlotte M. Deane Nucleic Acids Research 2013; doi: 10.1093/nar/gkt331 Article Bibtex

Target sequence* Upload the .fasta (or .fas, .faa, .fa, .txt) file of the sequence of the membrane protein you want to model. Or, alternatively, you can paste the protein sequence (header is optional) in the text box provided.
Example sequence fasta file
Please note that uploading files requires Flash to be enabled. Try using Firefox if another browser does not work. — or paste your sequence below Template structure* Upload the .pdb file of the protein you want to use as a template. Or, alternatively, enter the PDB code and the file will be downloaded automatically.
Example template file or use PDB code 2VT4
Please note that uploading files requires Flash to be enabled. Try using Firefox if another browser does not work. — or enter PDB code Template chain * The template chain to use. Example: A
Note that chain identifiers are case sensitive. Model >>>

* denotes mandatory field