pdb Hchain Lchain model antigen_chain antigen_type antigen_het_name antigen_name short_header date compound organism heavy_species light_species antigen_species authors resolution method r_free r_factor scfv engineered heavy_subclass light_subclass light_ctype affinity delta_g affinity_method temperature pmid 5bvp H L 0 I protein NA interleukin-1 beta IMMUNE SYSTEM 06/05/15 The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1beta HOMO SAPIENS homo sapiens homo sapiens homo sapiens Rondeau, J.M. 2.2 X-RAY DIFFRACTION 0.231 0.188 False True IGHV3 IGKV6 Kappa None None None None None