SAbPred: ANARCI

Antigen receptor Numbering And Receptor ClassificatIon.

ANARCI is a tool for numbering amino-acid sequences of antibody and T-cell receptor variable domains.
Use the form below to identify domains and annotate them with either the IMGT, Chothia, Kabat, Martin (Enhanced Chothia) or AHo numbering scheme.
TCR sequences can only be numbered with IMGT or AHo schemes.
ANARCI aligns a given sequence to a database of Hidden Markov Models that describe the germline sequences of antibody and TCR domain types.
The most significant alignment predicts the domain type and species (*) of the input sequence.

ANARCI is freely available to download from our GitHub page.

For a full description of the pipeline, or if you use this software, please refer to: Dunbar J and Deane CM. ANARCI: Antigen receptor numbering and receptor classification. Bioinformatics (2016)

> Sequence submission form

(*) NB: By default ANARCI restricts germilines to human and mouse to ensure sequence numbering remains robust as new germline data becomes available. If you wish to use other germline species, you can do so by downloading ANARCI from GitHub here

Submit single sequence:

load example

or upload multiple sequences as a fasta file:

Choose a numbering scheme:

IMGT Kabat Chothia Martin AHo

Choose an output format:

Comma separated value (csv) file (horizontal format) Plain text (txt) file (vertical format)

Restrict to immunoglobulin domains only