ABodyBuilder

Antibody Modelling Submission

  • ABodyBuilder can be used to produce models of the antibody Fv region, or nanobodies.
  • Submit heavy and light chain sequences to the forms below and ABodyBuilder will
    • Number the sequences with ANARCI
    • Choose the best templates for the VH and VL domains separately using SAbDab
    • Predict the VH-VL orientation using ABangle and place the template domains in the predicted pose
    • Model the CDR loops with FREAD. FREAD databases updated on 30 Sep, 2017.
    • Generate side chains with PEARS.
    • Renumber the final models with ANARCI
    • Annotate the estimated model accuracy, recognise potential developability issues and visualise different regions of the structure.
  • Models generated here can then be used in the Antibody-iPatch paratope prediction and EpiPred epitope prediction algorithms.

  • For a full description of the pipeline, or if you use this software, please refer to:
    Leem J, et al. ABodyBuilder: automated antibody structure prediction with data-driven accuracy estimation. mAbs. (2016)

    Further instructions and video for using the modelling server can be found on the SAbPred help page. [Example output]
Submit a heavy chain sequence and a light chain sequence [Help]


Advanced options


Currently running 0 job(s). Max permitted is 20

Job IDJob typeSubmission timeStatus
SEJ (?)ModellingFriday 17th of November 2017 02:44:08 PMDone
SEJ (?)ModellingFriday 17th of November 2017 08:34:42 AMFailed
SEJ (?)ModellingFriday 17th of November 2017 08:32:01 AMDone
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SEJ (?)ModellingThursday 16th of November 2017 09:29:13 PMDone
SEJ (?)ModellingThursday 16th of November 2017 08:19:10 PMDone
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SEJ (?)ModellingTuesday 14th of November 2017 05:28:38 PMDone
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SEJ (?)ModellingMonday 13th of November 2017 02:37:25 AMFailed
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SEJ (?)ModellingWednesday 8th of November 2017 06:22:23 PMDone
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SEJ (?)ModellingTuesday 7th of November 2017 08:10:15 PMDone
SEJ (?)ModellingTuesday 7th of November 2017 03:26:41 PMDone
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SEJ (?)ModellingTuesday 7th of November 2017 06:57:43 AMFailed
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SEJ (?)ModellingMonday 6th of November 2017 07:49:06 PMDone
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SEJ (?)ModellingSunday 5th of November 2017 02:54:11 PMDone
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SEJ (?)ModellingSunday 5th of November 2017 12:21:02 PMDone
SEJ (?)ModellingFriday 3rd of November 2017 05:25:40 PMDone
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SEJ (?)ModellingThursday 2nd of November 2017 11:59:44 PMDone
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SEJ (?)ModellingThursday 2nd of November 2017 06:45:40 PMDone
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SEJ (?)ModellingWednesday 1st of November 2017 09:51:24 PMDone
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SEJ (?)ModellingMonday 30th of October 2017 03:37:05 PMDone
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SEJ (?)ModellingSaturday 28th of October 2017 04:37:30 PMDone
SEJ (?)ModellingFriday 27th of October 2017 10:12:45 PMDone
SEJ (?)ModellingFriday 27th of October 2017 07:42:01 AMDone
SEJ (?)ModellingThursday 26th of October 2017 04:59:19 PMDone
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SEJ (?)ModellingThursday 26th of October 2017 07:05:19 AMDone
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SEJ (?)ModellingWednesday 25th of October 2017 06:26:42 PMDone
SEJ (?)ModellingWednesday 25th of October 2017 10:39:29 AMDone
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SEJ (?)ModellingTuesday 24th of October 2017 10:19:55 AMDone
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SEJ (?)ModellingMonday 23rd of October 2017 11:23:43 PMDone
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SEJ (?)ModellingMonday 23rd of October 2017 05:09:41 PMFailed
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SEJ (?)ModellingMonday 23rd of October 2017 09:27:23 AMDone
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SEJ (?)ModellingSunday 22nd of October 2017 07:30:15 PMDone
SEJ (?)ModellingSunday 22nd of October 2017 06:12:27 PMDone
SEJ (?)ModellingSaturday 21st of October 2017 10:38:59 PMDone
SEJ (?)ModellingFriday 20th of October 2017 09:49:18 PMDone
SEJ (?)ModellingFriday 20th of October 2017 12:14:22 PMDone
SEJ (?)ModellingFriday 20th of October 2017 03:42:49 AMDone