TAP: Therapeutic Antibody Profiler

How similar is your antibody to clinical-stage therapeutics?

The developability guidelines used by TAP are explained in 'Five Computational Developability Guidelines for Therapeutic Antibody Profiling', which is now published in PNAS (link).

To use this application, you only require an amino acid antibody variable domain heavy and light chain sequence.

The Therapeutic Antibody Profiler (TAP) compares your antibody variable domain sequence against five developability guidelines derived from clinical-stage therapeutic values.

TAP uses ABodyBuilder, with side-chains modelled by PEARS, to generate a model structure of your antibody. The standard implementation takes around 30 seconds.

If the H3 loop can not be modelled using FREAD, it defaults to modelling the loop with MODELLER (+~3mins). SPHINX can also be used for more accurate modelling, but expect a large increase in runtime.

TAP then calculates the following properties (explained in the paper) to see if your antibody design is commenserate with those of clinical-stage therapeutics:

  1. Total CDR Length
  2. Patches of Surface Hydrophobicity (PSH) metric across the CDR Vicinity
  3. Patches of Positive Charge (PPC) metric across the CDR Vicinity
  4. Patches of Negative Charge (PNC) metric across the CDR Vicinity
  5. Structural Fv Charge Symmetry Parameter (SFvCSP)

TAP also outputs...

  • An interactive representation of your antibody model, allowing you to visualise hydrophobic/charge patches on the Van der Waals surface. The model is downloadable.
  • A representation showing predicted model accuracy, communicating the confidence you should have in our metric values
  • Sequence Liabilites likely to lead to post- or co-translational modification
  • North-defined length-independent Canonical Forms (excluding the H3 loop)

For a sample TAP output, please click here.

If you are not sure how to use TAP, please look at the submission guidelines here.


TAP: Single Antibody Submission [Help]


Options

If FREAD cannot model your CDRH3 loop, should ABodyBuilder use Modeller or Sphinx (a hybrid ab initio/knowledge-based method - more accurate, but expect a longer runtime)?


Currently running 4 job(s). Max permitted is 20

Job IDJob typeSubmission timeStatus
SEJ (?)TAPWednesday 20th of February 2019 11:45:49 AMDone
SEJ (?)TAPWednesday 20th of February 2019 11:29:04 AMDone
SEJ (?)TAPWednesday 20th of February 2019 11:21:03 AMDone
SEJ (?)TAPWednesday 20th of February 2019 08:05:50 AMDone
SEJ (?)TAPWednesday 20th of February 2019 01:30:17 AMDone
SEJ (?)TAPWednesday 20th of February 2019 01:28:38 AMDone
SEJ (?)TAPWednesday 20th of February 2019 01:25:18 AMDone
SEJ (?)TAPWednesday 20th of February 2019 12:28:13 AMDone
SEJ (?)TAPWednesday 20th of February 2019 12:09:16 AMDone
SEJ (?)TAPTuesday 19th of February 2019 10:12:00 PMDone
SEJ (?)TAPTuesday 19th of February 2019 10:09:03 PMDone
SEJ (?)TAPTuesday 19th of February 2019 08:42:43 PMDone
SEJ (?)TAPTuesday 19th of February 2019 08:22:27 PMDone
SEJ (?)TAPTuesday 19th of February 2019 07:49:07 PMDone
SEJ (?)TAPTuesday 19th of February 2019 07:43:53 PMDone
SEJ (?)TAPTuesday 19th of February 2019 07:37:13 PMDone
SEJ (?)TAPTuesday 19th of February 2019 07:08:02 PMDone
SEJ (?)TAPTuesday 19th of February 2019 05:39:37 PMDone
SEJ (?)TAPTuesday 19th of February 2019 05:32:04 PMDone
SEJ (?)TAPTuesday 19th of February 2019 04:29:46 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:20:17 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:20:11 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:20:06 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:20:01 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:19:56 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:19:50 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:19:45 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:19:39 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:19:32 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:59 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:53 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:47 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:41 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:35 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:29 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:24 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:19 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:14 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:17:08 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:43 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:35 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:28 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:20 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:13 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:05 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:14:59 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:14:51 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:14:46 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:14:40 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:12:25 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:12:19 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:12:05 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:12:00 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:11:55 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:11:50 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:11:44 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:11:38 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:11:33 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:41 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:35 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:30 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:24 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:19 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:14 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:07 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:08:01 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:07:55 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:07:48 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:07:26 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:04:09 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:04:03 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:53 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:42 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:34 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:25 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:21 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:15 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:13 PMDone
SEJ (?)TAPTuesday 19th of February 2019 03:03:03 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:46:58 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:46:08 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:45:44 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:45:18 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:44:58 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:44:34 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:44:17 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:43:42 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:43:21 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:43:04 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:40:42 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:36:46 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:36:06 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:35:38 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:35:13 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:34:49 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:34:30 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:34:05 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:33:32 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:32:49 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:32:24 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:31:20 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:30:59 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:30:34 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:30:11 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:18:49 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:17:48 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:17:44 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:17:08 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:15:43 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:12:07 PMDone
SEJ (?)TAPTuesday 19th of February 2019 02:10:00 PMDone
SEJ (?)TAPTuesday 19th of February 2019 01:47:20 PMDone
SEJ (?)TAPTuesday 19th of February 2019 01:40:52 PMDone
SEJ (?)TAPTuesday 19th of February 2019 12:35:35 PMDone
SEJ (?)TAPTuesday 19th of February 2019 12:34:57 PMDone
SEJ (?)TAPTuesday 19th of February 2019 09:34:54 AMDone
SEJ (?)TAPTuesday 19th of February 2019 09:23:42 AMDone
SEJ (?)TAPTuesday 19th of February 2019 08:53:49 AMDone
SEJ (?)TAPTuesday 19th of February 2019 08:23:06 AMDone
SEJ (?)TAPTuesday 19th of February 2019 08:21:02 AMDone
SEJ (?)TAPTuesday 19th of February 2019 08:19:08 AMDone
SEJ (?)TAPTuesday 19th of February 2019 08:16:16 AMDone
SEJ (?)TAPTuesday 19th of February 2019 03:15:08 AMDone
SEJ (?)TAPTuesday 19th of February 2019 02:51:12 AMDone
SEJ (?)TAPMonday 18th of February 2019 08:06:44 PMDone
SEJ (?)TAPMonday 18th of February 2019 07:12:02 PMDone
SEJ (?)TAPMonday 18th of February 2019 06:00:03 PMRunning
SEJ (?)TAPMonday 18th of February 2019 05:59:50 PMRunning
SEJ (?)TAPMonday 18th of February 2019 05:57:17 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:57:10 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:57:03 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:56:57 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:56:50 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:56:43 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:54:04 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:55 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:48 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:41 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:35 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:28 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:22 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:53:13 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:50:35 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:50:27 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:50:20 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:50:13 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:50:06 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:50:00 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:49:54 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:49:46 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:47:13 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:47:04 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:46:57 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:46:49 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:46:41 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:46:34 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:46:26 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:46:17 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:42:32 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:42:24 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:42:18 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:42:10 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:42:03 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:41:56 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:41:50 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:41:42 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:55 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:48 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:40 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:34 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:27 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:20 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:14 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:38:07 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:35:15 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:35:07 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:35:00 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:34:53 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:34:46 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:34:39 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:34:32 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:34:25 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:31:31 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:31:22 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:31:15 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:31:08 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:31:01 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:30:54 PMRunning
SEJ (?)TAPMonday 18th of February 2019 05:30:47 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:30:40 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:28:03 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:55 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:48 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:41 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:34 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:27 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:21 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:27:14 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:24:28 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:24:20 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:24:13 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:24:06 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:23:59 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:23:51 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:23:44 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:23:38 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:48 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:40 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:33 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:26 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:20 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:13 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:20:05 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:19:58 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:17:25 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:17:11 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:17:01 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:16:53 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:16:46 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:16:39 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:16:31 PMDone
SEJ (?)TAPMonday 18th of February 2019 05:16:24 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:49:19 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:49:09 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:49:01 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:48:51 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:48:44 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:48:37 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:48:30 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:48:22 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:45:11 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:45:00 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:44:51 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:44:43 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:44:35 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:44:28 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:44:20 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:44:12 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:41:06 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:40:56 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:40:47 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:40:38 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:40:33 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:40:16 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:40:07 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:39:57 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:36:43 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:36:33 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:36:20 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:36:08 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:35:59 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:35:52 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:35:04 PMDone
SEJ (?)TAPMonday 18th of February 2019 04:34:54 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:03:25 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:03:15 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:03:06 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:02:58 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:02:49 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:02:40 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:02:30 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:00:27 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:00:16 PMDone
SEJ (?)TAPMonday 18th of February 2019 03:00:06 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:59:54 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:59:44 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:59:32 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:59:22 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:56:44 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:56:31 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:56:11 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:55:55 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:55:35 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:50:59 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:50:45 PMDone
SEJ (?)TAPMonday 18th of February 2019 02:50:24 PMDone
SEJ (?)TAPMonday 18th of February 2019 08:00:56 AMDone
SEJ (?)TAPMonday 18th of February 2019 07:54:15 AMDone
SEJ (?)TAPMonday 18th of February 2019 04:50:16 AMDone
SEJ (?)TAPMonday 18th of February 2019 03:08:04 AMDone
SEJ (?)TAPMonday 18th of February 2019 02:28:57 AMDone
SEJ (?)TAPMonday 18th of February 2019 02:27:15 AMDone
SEJ (?)TAPMonday 18th of February 2019 02:15:25 AMDone
SEJ (?)TAPMonday 18th of February 2019 12:16:26 AMDone
SEJ (?)TAPMonday 18th of February 2019 12:14:51 AMDone
SEJ (?)TAPMonday 18th of February 2019 12:10:36 AMDone
SEJ (?)TAPSunday 17th of February 2019 02:56:25 PMDone
SEJ (?)TAPSunday 17th of February 2019 01:09:53 PMDone
SEJ (?)TAPSunday 17th of February 2019 12:49:51 PMDone
SEJ (?)TAPSunday 17th of February 2019 12:45:20 PMDone
SEJ (?)TAPSunday 17th of February 2019 12:34:54 PMDone
SEJ (?)TAPSaturday 16th of February 2019 11:43:22 PMDone
SEJ (?)TAPSaturday 16th of February 2019 09:58:51 PMDone
SEJ (?)TAPSaturday 16th of February 2019 09:56:48 PMDone
SEJ (?)TAPSaturday 16th of February 2019 09:55:07 PMDone
SEJ (?)TAPSaturday 16th of February 2019 09:47:00 PMDone
SEJ (?)TAPSaturday 16th of February 2019 09:02:31 PMDone
SEJ (?)TAPSaturday 16th of February 2019 08:59:53 PMDone
SEJ (?)TAPSaturday 16th of February 2019 07:14:27 AMDone
SEJ (?)TAPFriday 15th of February 2019 11:08:25 PMDone
SEJ (?)TAPFriday 15th of February 2019 09:48:00 PMDone
SEJ (?)TAPFriday 15th of February 2019 08:38:03 PMDone
SEJ (?)TAPFriday 15th of February 2019 07:52:25 PMDone
SEJ (?)TAPFriday 15th of February 2019 07:45:03 PMDone
SEJ (?)TAPFriday 15th of February 2019 12:48:52 PMDone
SEJ (?)TAPFriday 15th of February 2019 12:35:31 PMDone
SEJ (?)TAPThursday 14th of February 2019 10:25:11 PMDone
SEJ (?)TAPThursday 14th of February 2019 06:41:04 PMDone
SEJ (?)TAPThursday 14th of February 2019 06:38:52 PMDone
SEJ (?)TAPThursday 14th of February 2019 06:32:36 PMDone
SEJ (?)TAPThursday 14th of February 2019 06:28:03 PMDone
SEJ (?)TAPThursday 14th of February 2019 05:59:14 PMDone
SEJ (?)TAPWednesday 13th of February 2019 08:56:39 AMDone
SEJ (?)TAPThursday 7th of February 2019 10:44:01 PMDone
SEJ (?)TAPThursday 7th of February 2019 10:34:26 PMDone
SEJ (?)TAPThursday 7th of February 2019 10:26:16 PMDone
SEJ (?)TAPThursday 7th of February 2019 10:09:33 PMDone
SEJ (?)TAPThursday 7th of February 2019 09:42:16 PMDone
SEJ (?)TAPThursday 7th of February 2019 09:32:02 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:31:00 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:29:54 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:28:45 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:27:15 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:26:09 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:24:00 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:21:31 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:17:02 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:13:54 PMDone
SEJ (?)TAPThursday 7th of February 2019 07:11:10 PMDone
SEJ (?)TAPThursday 7th of February 2019 10:56:56 AMRunning
SEJ (?)TAPThursday 7th of February 2019 09:51:06 AMFailed
SEJ (?)TAPThursday 7th of February 2019 09:50:18 AMFailed
SEJ (?)TAPMonday 4th of February 2019 09:25:41 AMDone
SEJ (?)TAPMonday 4th of February 2019 09:25:37 AMDone
SEJ (?)TAPMonday 4th of February 2019 09:22:34 AMDone
SEJ (?)TAPFriday 1st of February 2019 10:51:19 PMDone
SEJ (?)TAPTuesday 29th of January 2019 09:06:25 PMDone
SEJ (?)TAPTuesday 29th of January 2019 09:02:38 PMDone
SEJ (?)TAPMonday 28th of January 2019 09:48:42 PMDone
SEJ (?)TAPMonday 28th of January 2019 09:39:40 PMDone
SEJ (?)TAPMonday 28th of January 2019 06:13:07 PMDone
SEJ (?)TAPMonday 28th of January 2019 04:14:00 PMDone
SEJ (?)TAPMonday 28th of January 2019 04:10:15 PMDone
SEJ (?)TAPMonday 28th of January 2019 04:06:16 PMDone
SEJ (?)TAPMonday 28th of January 2019 03:59:10 PMDone
SEJ (?)TAPMonday 28th of January 2019 03:52:32 PMDone
SEJ (?)TAPMonday 28th of January 2019 03:50:53 PMDone
SEJ (?)TAPMonday 28th of January 2019 03:40:01 PMDone
SEJ (?)TAPMonday 28th of January 2019 10:54:29 AMDone
SEJ (?)TAPSaturday 26th of January 2019 08:43:37 AMDone
SEJ (?)TAPSaturday 26th of January 2019 01:15:18 AMDone
SEJ (?)TAPFriday 25th of January 2019 09:40:30 PMDone
SEJ (?)TAPFriday 25th of January 2019 09:38:34 PMDone
SEJ (?)TAPFriday 25th of January 2019 06:46:45 PMDone
SEJ (?)TAPFriday 25th of January 2019 06:19:51 PMDone
SEJ (?)TAPFriday 25th of January 2019 03:37:10 PMDone
SEJ (?)TAPFriday 25th of January 2019 03:34:15 PMDone
SEJ (?)TAPThursday 24th of January 2019 10:28:45 PMDone
SEJ (?)TAPThursday 24th of January 2019 10:25:20 PMFailed
SEJ (?)TAPThursday 24th of January 2019 08:55:34 PMDone
SEJ (?)TAPThursday 24th of January 2019 08:52:33 PMDone
SEJ (?)TAPThursday 24th of January 2019 08:31:32 PMDone
SEJ (?)TAPWednesday 23rd of January 2019 07:25:41 PMDone
SEJ (?)TAPTuesday 22nd of January 2019 06:35:59 PMDone
SEJ (?)TAPTuesday 22nd of January 2019 05:00:49 PMDone
SEJ (?)TAPTuesday 22nd of January 2019 03:33:48 PMDone
SEJ (?)TAPTuesday 22nd of January 2019 03:30:22 PMDone