Therapeutic Antibody Database

Explore the Structures of Therapeutic Antibodies Deposited in the PDB

 

The following table maps antibody therapeutics to their Protein Data Bank (PDB) structures. These therapeutics have all advanced to at least Phase II of clinical trials. Some have been withdrawn from the market, or had their clinical trials terminated. Please let us know if we have missed any post-Phase I therapeutic structures by sending an email to opig <~at~> stats.ox.ac.uk.

This page was last updated on 24th July, 2018.

 
Antibody TherapeuticLinks to Annotated Structures (Bound/Unbound, Resolution)
Abituzumab
  • 4o02 (Bound Fab, 3.61Å)
Adalimumab
  • 4nyl (Unbound Fab, 2.80Å)
  • 3wd5 (Bound Fab, 3.10Å)
Aducanumab
  • 6cnr (Unbound Fab, 2.09Å)
  • 6co3 (Bound Fab, 2.38Å)
Alemtuzumab
  • 1bey (Unbound Fab, 3.25Å)
  • 1ce1 (Bound Fab, 1.90Å)
Amatuximab
  • 4f33 (Unbound Fab, 1.75Å)
  • 4f3f (Bound Fab, 2.65Å)
Andecaliximab
  • 5th9 (Bound Fab, 3.00Å)
Anifrolumab
  • 4qxg (Unbound Fab, 2.30Å)
Atezolizumab
  • 5xxy (Bound Fab, 2.90Å)
  • 5x8l (Bound Fab, 3.10Å)
Avelumab
  • 5grj (Bound Fab, 3.21Å)
Bapineuzumab
  • 4ojf (Bound Fab, 2.00Å)
  • 4onf (Bound Fab, 2.00Å)
  • 4ong (Bound Fab, 2.20Å)
  • 4hix (Bound Fab, 2.20Å)
Basiliximab
  • 1mim (Unbound Fab, 2.60Å)
  • 3iu3 (Bound Fab, 2.90Å)
Belimumab
  • 5y9j (Bound Fab, 2.05Å)
  • 6fxn (Bound Fab, 2.90Å)
Bezlotoxumab
  • 4np4 (Bound Fab, 2.89Å)
Bimagrumab
  • 5nhw (Unbound Fab, 1.78Å)
Briakinumab
  • 5n2k (Unbound Fab, 2.22Å)
Canakinumab
  • 4g5z (Unbound Fab, 1.83Å)
  • 5bvj (Unbound Fab, 2.00Å)
  • 4g6j (Bound Fab, 2.03Å)
  • 5bvp (Bound Fab, 2.20Å)
Carlumab
  • 4dn3 (Unbound Fab, 2.60Å)
  • 4dn4 (Bound Fab, 2.80Å)
Certolizumab
  • 5wuv (Unbound Fab, 1.95Å)
  • 5wux (Bound Fab, 2.90Å)
Cetuximab
  • 1yy8 (Unbound Fab, 2.00Å)
  • 5th2 (Bound Fab, 1.84Å)
  • 4gw5 (Bound Fab, 2.20Å)
  • 4gw1 (Bound Fab, 2.24Å)
  • 5f88 (Bound Fab, 2.48Å)
  • 5hyq (Bound Fab, 2.48Å)
  • 5id0 (Bound Fab, 2.48Å)
  • 5ir1 (Bound Fab, 2.48Å)
  • 5ivz (Bound Fab, 2.48Å)
  • 5iv2 (Bound Fab, 2.48Å)
  • 5t1k (Bound Fab, 2.48Å)
  • 5t1l (Bound Fab, 2.48Å)
  • 5id1 (Bound Fab, 2.49Å)
  • 5euk (Bound Fab, 2.50Å)
  • 5ff6 (Bound Fab, 2.50Å)
  • 5icy (Bound Fab, 2.50Å)
  • 5iop (Bound Fab, 2.50Å)
  • 5itf (Bound Fab, 2.51Å)
  • 5etu (Bound Fab, 2.53Å)
  • 5t1m (Bound Fab, 2.53Å)
  • 5esq (Bound Fab, 2.55Å)
  • 5icz (Bound Fab, 2.55Å)
  • 5i2i (Bound Fab, 2.55Å)
  • 5icx (Bound Fab, 2.60Å)
  • 1yy9 (Bound Fab, 2.61Å)
  • 5hpm (Bound Fab, 2.67Å)
  • 4krp (Bound Fab, 2.82Å)
  • 4kro (Bound Fab, 3.05Å)
Coltuximab
  • 6ani (Bound Fab, 2.40Å)
Crenezumab
  • 5kmv (Unbound Fab, 2.50Å)
  • 5vzy (Bound Fab, 2.32Å)
Daclizumab
  • 3nfs (Unbound Fab, 2.60Å)
  • 3nfp (Bound Fab, 2.86Å)
Drozitumab
  • 4od2 (Bound Fab, 3.20Å)
Durvalumab
  • 5xj4 (Bound scFv, 2.30Å)
  • 5x8m (Bound Fab, 2.67Å)
Eculizumab
  • 5i5k (Bound Fab, 4.20Å)
Efalizumab
  • 3eo9 (Unbound Fab, 1.80Å)
  • 3eoa (Bound Fab, 2.80Å)
  • 3eob (Bound Fab, 3.60Å)
Epratuzumab
  • 5vkk (Unbound Fab, 2.01Å)
Etaracizumab
  • 6avq (Bound Fab, 35Å - ELECTRON MICROSCOPY)
  • 6avr (Bound Fab, 35Å - ELECTRON MICROSCOPY)
  • 6avu (Bound Fab, 35Å - ELECTRON MICROSCOPY)
Fresolimumab
  • 3eo0 (Unbound Fab, 1.75Å)
  • 3eo1 (Bound Fab, 3.10Å)
Gantenerumab
  • 5csz (Bound Fab, 1.80Å)
Gevokizumab
  • 4g6k (Unbound Fab, 1.90Å)
  • 4g6m (Bound Fab, 1.81Å)
Guselkumab
  • 4m6m (Unbound Fab, 2.00Å)
  • 4m6n (Unbound Fab, 2.00Å)
Ibalizumab
  • 3o2d (Bound Fab, 2.19Å)
Idarucizumab
  • 4jn2 (Unbound Fab, 1.71Å)
  • 4jn1 (Unbound Fab, 1.89Å)
Infliximab
  • 5vh3 (Unbound Fab, 2.00Å)
  • 5vh4 (Unbound Fab, 2.00Å)
  • 4g3y (Bound Fab, 2.60Å)
Ipilimumab
  • 5tru (Bound Fab, 3.00Å)
Isatuximab
  • 4cmh (Bound Fab, 1.53Å)
Lampalizumab
  • 4d9q (Bound Fab, 2.28Å)
Lanadelumab
  • 4pub (Unbound Fab, 1.75Å)
  • 4ogy (Bound Fab, 2.10Å)
  • 4ogx (Bound Fab, 2.40Å)
Lebrikizumab
  • 4i77 (Bound Fab, 1.90Å)
Matuzumab
  • 3c08 (Unbound Fab, 2.15Å)
  • 3c09 (Bound Fab, 3.20Å)
Motavizumab
  • 3qwo (Bound Fab, 1.90Å)
  • 4jlr (Bound Fab, 2.71Å)
  • 3ixt (Bound Fab, 2.75Å)
  • 4zyp (Bound Fab, 5.50Å)
Muromonab
  • 1sy6 (Bound Fab, 2.10Å)
Natalizumab
  • 4irz (Bound Fab, 2.84Å)
Necitumumab
  • 3b2u (Bound Fab, 2.54Å)
  • 3b2v (Bound Fab, 3.30Å)
Nimotuzumab
  • 3gkw (Unbound Fab, 2.50Å)
Nivolumab
  • 5ggq (Unbound Fab, 1.90Å)
Obinutuzumab
  • 3pp3 (Unbound Fab, 2.51Å)
  • 3pp4 (Bound Fab, 1.60Å)
Ofatumumab
  • 3giz (Unbound Fab, 2.20Å)
Olokizumab
  • 4cni (Bound Fab, 2.20Å)
Omalizumab
  • 4x7s (Unbound Fab, 1.90Å)
  • 2xa8 (Unbound Fab, 2.41Å)
  • 4x7t (Unbound Fab, 3.00Å)
  • 5hys (Bound Fab, 2.50Å)
  • 5g64 (Bound Fab, 3.72Å)
Onartuzumab
  • 4k3j (Bound Fab, 2.80Å)
Opicinumab
  • 4oqt (Bound Fab, 3.23Å)
Palivizumab
  • 2hwz (Unbound Fab, 1.80Å)
Panitumumab
  • 5sx5 (Bound Fab, 2.50Å)
  • 5sx4 (Bound Fab, 2.80Å)
Pembrolizumab
  • 5dk3 (Unbound Fc, 2.28Å)
  • 5ggs (Bound Fab, 2.00Å)
  • 5b8c (Bound Fv, 2.15Å)
  • 5jxe (Bound Fab, 2.90Å)
Pertuzumab
  • 4lly (Unbound Fab, 1.60Å)
  • 4llw (Unbound Fab, 1.95Å)
  • 4llu (Unbound Fab, 2.16Å)
  • 1s78 (Bound Fab, 3.25Å)
Pinatuzumab
  • 6and (Bound Fab, 1.75Å)
Ponezumab
  • 3u0t (Bound Fab, 2.50Å)
Ramucirumab
  • 3s34 (Unbound Fab, 2.20Å)
  • 3s36 (Bound Fab, 3.20Å)
Ranibizumab
  • 1cz8 (Bound Fab, 2.40Å)
Rituximab
  • 4kaq (Unbound Fab, 2.48Å)
  • 2osl (Bound Fab, 2.60Å)
Rontalizumab
  • 4z5r (Bound Fab, 3.00Å)
Sifalimumab
  • 4ypg (Bound Fab, 3.00Å)
Solanezumab
  • 4xxd (Bound Fab, 2.41Å)
Suvratoxumab
  • 4u6v (Bound Fab, 2.56Å)
Tanezumab
  • 4edw (Bound Fab, 2.48Å)
Tezepelumab
  • 5j13 (Bound Fab, 2.30Å)
Tralokinumab
  • 5l6y (Bound Fab, 1.99Å)
Trastuzumab
  • 4ioi (Bound Fab, 1.95Å)
  • 4hjg (Bound Fab, 2.00Å)
  • 4hkz (Bound Fab, 2.08Å)
Tremelimumab
  • 5ggv (Bound Fab, 2.00Å)
Ustekinumab
  • 3hmw (Unbound Fab, 3.00Å)
  • 3hmx (Bound Fab, 3.00Å)