Details for 3mff

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Structure information

1F1E8Hu TCR

Item	Info
PDB	3mff
Organism	HOMO SAPIENS
Method	X-RAY DIFFRACTION
Resolution	2Å
Number of TCRs	2

Paired chains information

This PDB has 2 TCR(s).

B / A

TCR Details:

Item	Info
VB chain	B
VA chain	A
VB IMGT details	TRBV29/TRBJ2
VA IMGT details	TRAV14/TRAJ52
Species	mouse

Numbered sequence

Chain type

Chain ID

FASTA/Annotation file

IMGT numbered sequence (Framework/CDR)

FASTA file

B2	B3	B4	B5	B6	B7	B8	B9
M	K	V	T	Q	M	P	R
B10	B11	B12	B13	B14	B15	B16	B17
Y	L	I	K	R	M	G	E
B18	B19	B20	B21	B22	B23	B24	B25
N	V	L	L	E	C	G	Q
B26	B27	B28	B29	B37	B38	B39	B40
D	M	S	H	E	T	M	Y
B41	B42	B43	B44	B45	B46	B47	B48
W	Y	R	Q	D	P	G	L
B49	B50	B51	B52	B53	B54	B55	B56
G	L	Q	L	I	Y	I	S
B57	B58	B63	B64	B65	B66	B67	B68
Y	D	V	D	S	N	S	E
B69	B70	B71	B72	B74	B75	B76	B77
G	D	I	P	K	G	Y	R
B78	B79	B80	B81	B83	B84	B85	B86
V	S	R	K	K	R	E	H
B87	B88	B89	B90	B91	B92	B93	B94
F	S	L	I	L	D	S	A
B95	B96	B97	B98	B99	B100	B101	B102
K	T	N	Q	T	S	V	Y
B103	B104	B105	B106	B107	B108	B109	B110
F	C	A	S	S	L	A	G
B111	B112	B113	B114	B115	B116	B117	B118
T	G	N	Y	E	Q	Y	F
B119	B120	B121	B122	B123	B124	B125	B126
G	P	G	T	R	L	T	V
B127
T

FASTA file

A3	A4	A5	A6	A7	A8	A9	A10
Q	V	R	Q	S	P	Q	S
A11	A12	A13	A14	A15	A16	A17	A18
L	T	V	W	E	G	E	T
A19	A20	A21	A22	A23	A24	A25	A26
T	I	L	N	C	S	Y	E
A27	A28	A29	A36	A37	A38	A39	A40
N	S	A	F	D	Y	F	P
A41	A42	A43	A44	A45	A46	A47	A48
W	Y	Q	Q	F	P	G	E
A49	A50	A51	A52	A53	A54	A55	A56
G	P	A	L	L	I	A	I
A57	A58	A59	A63	A64	A65	A66	A67
R	S	V	S	D	K	K	E
A68	A74	A75	A76	A77	A78	A79	A80
D	G	R	F	T	I	F	F
A81	A82	A83	A84	A85	A86	A87	A88
N	K	R	E	K	K	L	S
A89	A90	A91	A92	A93	A94	A95	A96
L	H	I	T	D	S	Q	P
A97	A98	A99	A100	A101	A102	A103	A104
G	D	S	A	T	Y	F	C
A105	A106	A107	A108	A109	A110	A113	A114
A	A	T	G	A	N	T	G
A115	A116	A117	A118	A119	A120	A121	A122
K	L	T	F	G	H	G	T
A123	A124	A125	A126	A127	A128
I	L	R	V	H	P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLAGTGNYEQY	None	13
CDRB2	SYDVDS	None	6
CDRB1	MSHET	None	5
CDRA3	AATGANTGKLT	None	11
CDRA2	IRSVSDK	None	7
CDRA1	NSAFDY	None	6

Orientation and docking angles:

Angle	Value
BC2	106.92°
BC1	71.88°
BA	-68.46°
AC2	73.85°
AC1	127.42°
dc	16.76Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
6g9q_HG	105.83°	72.82°	-66.70°	73.31°	126.81°	16.80Å	2.4
5m00_HG	105.73°	72.66°	-66.26°	73.27°	127.19°	16.70Å	2.7
5m01_HG	104.90°	73.05°	-67.01°	73.42°	126.75°	16.70Å	2.9
5m02_HG	104.84°	73.41°	-67.56°	72.98°	126.46°	16.68Å	3.0
5tje_HG	107.04°	73.34°	-68.47°	71.17°	127.35°	16.67Å	3.1

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1n4x_IM	107.07°	73.94°	-70.53°	72.40°	121.78°	15.58Å	6.6
1jv5_BA	111.45°	73.74°	-67.77°	74.39°	122.07°	15.49Å	7.4
4yfl_FI	106.92°	71.36°	-64.48°	73.60°	120.95°	15.85Å	7.7
5jue_HL	106.42°	70.98°	-68.16°	76.41°	119.66°	16.06Å	8.3
4uim_AB	109.49°	71.42°	-65.63°	76.99°	119.77°	15.95Å	9.2

D / C

TCR Details:

Item	Info
VB chain	D
VA chain	C
VB IMGT details	TRBV29/TRBJ2
VA IMGT details	TRAV14/TRAJ52
Species	mouse

Numbered sequence

Chain type

Chain ID

FASTA/Annotation file

IMGT numbered sequence (Framework/CDR)

FASTA file

B2	B3	B4	B5	B6	B7	B8	B9
M	K	V	T	Q	M	P	R
B10	B11	B12	B13	B14	B15	B16	B17
Y	L	I	K	R	M	G	E
B18	B19	B20	B21	B22	B23	B24	B25
N	V	L	L	E	C	G	Q
B26	B27	B28	B29	B37	B38	B39	B40
D	M	S	H	E	T	M	Y
B41	B42	B43	B44	B45	B46	B47	B48
W	Y	R	Q	D	P	G	L
B49	B50	B51	B52	B53	B54	B55	B56
G	L	Q	L	I	Y	I	S
B57	B58	B63	B64	B65	B66	B67	B68
Y	D	V	D	S	N	S	E
B69	B70	B71	B72	B74	B75	B76	B77
G	D	I	P	K	G	Y	R
B78	B79	B80	B81	B83	B84	B85	B86
V	S	R	K	K	R	E	H
B87	B88	B89	B90	B91	B92	B93	B94
F	S	L	I	L	D	S	A
B95	B96	B97	B98	B99	B100	B101	B102
K	T	N	Q	T	S	V	Y
B103	B104	B105	B106	B107	B108	B109	B110
F	C	A	S	S	L	A	G
B111	B112	B113	B114	B115	B116	B117	B118
T	G	N	Y	E	Q	Y	F
B119	B120	B121	B122	B123	B124	B125	B126
G	P	G	T	R	L	T	V
B127
T

FASTA file

A3	A4	A5	A6	A7	A8	A9	A10
Q	V	R	Q	S	P	Q	S
A11	A12	A13	A14	A15	A16	A17	A18
L	T	V	W	E	G	E	T
A19	A20	A21	A22	A23	A24	A25	A26
T	I	L	N	C	S	Y	E
A27	A28	A29	A36	A37	A38	A39	A40
N	S	A	F	D	Y	F	P
A41	A42	A43	A44	A45	A46	A47	A48
W	Y	Q	Q	F	P	G	E
A49	A50	A51	A52	A53	A54	A55	A56
G	P	A	L	L	I	A	I
A57	A58	A59	A63	A64	A65	A66	A67
R	S	V	S	D	K	K	E
A68	A74	A75	A76	A77	A78	A79	A80
D	G	R	F	T	I	F	F
A81	A82	A83	A84	A85	A86	A87	A88
N	K	R	E	K	K	L	S
A89	A90	A91	A92	A93	A94	A95	A96
L	H	I	T	D	S	Q	P
A97	A98	A99	A100	A101	A102	A103	A104
G	D	S	A	T	Y	F	C
A105	A106	A107	A108	A109	A110	A113	A114
A	A	T	G	A	N	T	G
A115	A116	A117	A118	A119	A120	A121	A122
K	L	T	F	G	H	G	T
A123	A124	A125	A126	A127	A128
I	L	R	V	H	P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLAGTGNYEQY	None	13
CDRB2	SYDVDS	None	6
CDRB1	MSHET	None	5
CDRA3	AATGANTGKLT	None	11
CDRA2	IRSVSDK	None	7
CDRA1	NSAFDY	None	6

Orientation and docking angles:

Angle	Value
BC2	107.65°
BC1	72.18°
BA	-68.09°
AC2	72.85°
AC1	125.91°
dc	16.72Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
5tje_HG	107.04°	73.34°	-68.47°	71.17°	127.35°	16.67Å	2.6
2uwe_ML	108.04°	73.37°	-66.20°	73.74°	124.87°	16.70Å	2.6
6g9q_HG	105.83°	72.82°	-66.70°	73.31°	126.81°	16.80Å	2.6
2j8u_ML	107.93°	72.98°	-66.36°	73.99°	124.42°	16.81Å	2.7
2pxy_BA	107.69°	72.09°	-67.17°	74.08°	123.73°	16.39Å	2.7

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1n4x_IM	107.07°	73.94°	-70.53°	72.40°	121.78°	15.58Å	5.3
1jv5_BA	111.45°	73.74°	-67.77°	74.39°	122.07°	15.49Å	6.0
4yfl_FI	106.92°	71.36°	-64.48°	73.60°	120.95°	15.85Å	6.3
5jue_HL	106.42°	70.98°	-68.16°	76.41°	119.66°	16.06Å	7.4
12e8_HL	106.48°	69.23°	-70.96°	74.63°	118.60°	16.05Å	8.7

Available downloads

Additional links and files for download: see help for more details.

Item	Link
IMGT-numbered structure	Link
Non-annotated structure from the PDB	Link
Summary file for this TCR	Link
Link in the PDB	Link