TCR Details:

Item	Info
VB chain	E
VA chain	D
VB IMGT details	TRBV12/TRBJ2
VA IMGT details	TRAV12/TRAJ12
Species	human

Numbered sequence

Chain type	Chain ID	FASTA/Annotation file	IMGT numbered sequence (Framework/CDR)
VB	E	FASTA file	B1 B2 B3 B4 B5 B6 B7 B8 D A G V I Q S P B9 B10 B11 B12 B13 B14 B15 B16 R H E V T E M G B17 B18 B19 B20 B21 B22 B23 B24 Q Q V T L R C K B25 B26 B27 B28 B29 B37 B38 B39 P I S G H D Y L B40 B41 B42 B43 B44 B45 B46 B47 F W Y R Q T M M B48 B49 B50 B51 B52 B53 B54 B55 R G L E L L I Y B56 B57 B58 B63 B64 B65 B66 B67 F N N N V P I D B68 B69 B70 B71 B72 B73 B74 B75 D S G M P E D R B76 B77 B78 B79 B80 B81 B83 B84 F S A K M P N A B85 B86 B87 B88 B89 B90 B91 B92 S F S T L K I Q B93 B94 B95 B96 B97 B98 B99 B100 P S E P R D S A B101 B102 B103 B104 B105 B106 B107 B108 V Y F C A S S L B109 B110 B111 B112A B112 B113 B114 B115 W E K L A K N I B116 B117 B118 B119 B120 B121 B122 B123 Q Y F G A G T R B124 B125 B126 B127 L S V L
VA	D	FASTA file	A2 A3 A4 A5 A6 A7 A8 A9 K E V E Q D P G A10 A11 A12 A13 A14 A15 A16 A17 P L S V P E G A A18 A19 A20 A21 A22 A23 A24 A25 I V S L N C T Y A26 A27 A28 A29 A36 A37 A38 A39 S N S A F Q Y F A40 A41 A42 A43 A44 A45 A46 A47 M W Y R Q Y S R A48 A49 A50 A51 A52 A53 A54 A55 K G P E L L M Y A56 A57 A58 A63 A64 A65 A66 A67 T Y S S G N K E A68 A74 A75 A76 A77 A78 A79 A80 D G R F T A Q V A81 A82 A83 A84 A85 A86 A87 A88 D K S S K Y I S A89 A90 A91 A92 A93 A94 A95 A96 L F I R D S Q P A97 A98 A99 A100 A101 A102 A103 A104 S D S A T Y L C A105 A106 A107 A108 A109 A110 A113 A114 A M R G D S S Y A115 A116 A117 A118 A119 A120 A121 A122 K L I F G S G T A123 A124 A125 A126 A127 A128 R L L V R P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLWEKLAKNIQY	None	14
CDRB2	FNNNVP	None	6
CDRB1	SGHDY	None	5
CDRA3	AMRGDSSYKLI	None	11
CDRA2	TYSSGN	A2-6-B	6
CDRA1	NSAFQY	None	6

Orientation and docking angles:

Angle	Value
BC2	106.67°
BC1	75.56°
BA	-65.45°
AC2	75.52°
AC1	123.14°
dc	16.18Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
2jcc_ML	108.06°	74.29°	-65.45°	75.02°	124.73°	16.72Å	2.6
6v13_ED	106.65°	74.00°	-66.07°	74.03°	124.56°	16.59Å	2.7
2j8u_FE	108.31°	74.02°	-66.29°	74.42°	123.85°	16.69Å	2.8
2jcc_FE	109.08°	74.58°	-66.28°	75.05°	124.04°	16.62Å	2.9
7n2o_FD	106.34°	74.73°	-64.81°	77.13°	120.85°	15.94Å	3.0

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
4yfl_FI	106.92°	71.36°	-64.48°	73.60°	120.95°	15.85Å	5.2
1jv5_BA	111.45°	73.74°	-67.77°	74.39°	122.07°	15.49Å	5.9
1n4x_IM	107.07°	73.94°	-70.53°	72.40°	121.78°	15.58Å	6.4
5jue_HL	106.42°	70.98°	-68.16°	76.41°	119.66°	16.06Å	6.4
1nmc_HL	110.09°	71.80°	-64.06°	80.19°	120.88°	16.16Å	7.4

TCR Details:

Item	Info
VB chain	L
VA chain	K
VB IMGT details	TRBV12/TRBJ2
VA IMGT details	TRAV12/TRAJ12
Species	human

Numbered sequence

Chain type	Chain ID	FASTA/Annotation file	IMGT numbered sequence (Framework/CDR)
VB	L	FASTA file	B1 B2 B3 B4 B5 B6 B7 B8 D A G V I Q S P B9 B10 B11 B12 B13 B14 B15 B16 R H E V T E M G B17 B18 B19 B20 B21 B22 B23 B24 Q Q V T L R C K B25 B26 B27 B28 B29 B37 B38 B39 P I S G H D Y L B40 B41 B42 B43 B44 B45 B46 B47 F W Y R Q T M M B48 B49 B50 B51 B52 B53 B54 B55 R G L E L L I Y B56 B57 B58 B63 B64 B65 B66 B67 F N N N V P I D B68 B69 B70 B71 B72 B73 B74 B75 D S G M P E D R B76 B77 B78 B79 B80 B81 B83 B84 F S A K M P N A B85 B86 B87 B88 B89 B90 B91 B92 S F S T L K I Q B93 B94 B95 B96 B97 B98 B99 B100 P S E P R D S A B101 B102 B103 B104 B105 B106 B107 B108 V Y F C A S S L B109 B110 B111 B112A B112 B113 B114 B115 W E K L A K N I B116 B117 B118 B119 B120 B121 B122 B123 Q Y F G A G T R B124 B125 B126 B127 L S V L
VA	K	FASTA file	A2 A3 A4 A5 A6 A7 A8 A9 K E V E Q D P G A10 A11 A12 A13 A14 A15 A16 A17 P L S V P E G A A18 A19 A20 A21 A22 A23 A24 A25 I V S L N C T Y A26 A27 A28 A29 A36 A37 A38 A39 S N S A F Q Y F A40 A41 A42 A43 A44 A45 A46 A47 M W Y R Q Y S R A48 A49 A50 A51 A52 A53 A54 A55 K G P E L L M Y A56 A57 A58 A63 A64 A65 A66 A67 T Y S S G N K E A68 A74 A75 A76 A77 A78 A79 A80 D G R F T A Q V A81 A82 A83 A84 A85 A86 A87 A88 D K S S K Y I S A89 A90 A91 A92 A93 A94 A95 A96 L F I R D S Q P A97 A98 A99 A100 A101 A102 A103 A104 S D S A T Y L C A105 A106 A107 A108 A109 A110 A113 A114 A M R G D S S Y A115 A116 A117 A118 A119 A120 A121 A122 K L I F G S G T A123 A124 A125 A126 A127 A128 R L L V R P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLWEKLAKNIQY	None	14
CDRB2	FNNNVP	None	6
CDRB1	SGHDY	None	5
CDRA3	AMRGDSSYKLI	None	11
CDRA2	TYSSGN	A2-6-B	6
CDRA1	NSAFQY	None	6

Orientation and docking angles:

Angle	Value
BC2	112.41°
BC1	78.45°
BA	-59.63°
AC2	79.12°
AC1	121.28°
dc	16.17Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
5c08_ED	111.93°	80.00°	-60.13°	80.39°	121.87°	15.78Å	2.2
5c07_ED	112.10°	80.10°	-60.76°	80.35°	122.08°	15.77Å	2.5
5c0a_JI	110.98°	79.72°	-61.04°	79.90°	122.30°	15.78Å	2.7
5c0b_JI	112.28°	80.10°	-60.73°	80.73°	121.94°	15.83Å	2.7
5c0c_ED	112.16°	79.79°	-60.27°	81.04°	122.31°	15.89Å	2.7

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
3cvh_QR	113.65°	77.38°	-59.58°	79.78°	118.82°	15.93Å	3.0
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	3.6
5f45_HL	113.99°	76.58°	-57.10°	79.66°	119.86°	16.52Å	3.9
5dum_HL	112.74°	74.77°	-58.24°	80.30°	121.12°	16.51Å	4.1
4jj5_BA	113.30°	75.08°	-58.94°	79.43°	123.53°	16.49Å	4.2