Details for 6dfq

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Structure information

Mouse Diabetogenic TCR I.29

Item	Info
PDB	6dfq
Organism	MUS MUSCULUS
Method	X-RAY DIFFRACTION
Resolution	2.6Å
Number of TCRs	4

Paired chains information

This PDB has 4 TCR(s).

B / A

TCR Details:

Item	Info
VB chain	B
VA chain	A
VB IMGT details	TRBV1/TRBJ2
VA IMGT details	TRAV10/TRAJ53
Species	mouse

Numbered sequence

Chain type

Chain ID

FASTA/Annotation file

IMGT numbered sequence (Framework/CDR)

FASTA file

B1	B2	B3	B4	B5	B6	B7	B8
M	T	L	L	E	Q	N	P
B9	B10	B11	B12	B13	B14	B15	B16
R	W	R	L	V	P	R	G
B17	B18	B19	B20	B21	B22	B23	B24
Q	A	V	N	L	R	C	I
B25	B26	B27	B28	B29	B36	B37	B38
L	K	N	S	Q	Y	P	W
B39	B40	B41	B42	B43	B44	B45	B46
M	S	W	Y	Q	Q	D	L
B47	B48	B49	B50	B51	B52	B53	B54
Q	K	Q	L	Q	W	L	F
B55	B56	B57	B58	B63	B64	B65	B66
T	L	R	S	P	G	D	K
B67	B68	B69	B70	B71	B72	B73	B74
E	V	K	S	L	P	G	A
B75	B76	B77	B78	B79	B80	B81	B83
D	Y	L	A	T	R	V	T
B84	B85	B86	B87	B88	B89	B90	B91
D	T	E	L	R	L	Q	V
B92	B93	B94	B95	B98	B99	B100	B101
A	N	M	S	Q	G	R	T
B102	B103	B104	B105	B106	B107	B108	B109
L	Y	C	T	C	S	A	G
B110	B113	B114	B115	B116	B117	B118	B119
L	G	Y	E	Q	Y	F	G
B120	B121	B122	B123	B124	B125	B126	B127
P	G	T	R	L	T	V	L

FASTA file

A1	A2	A3	A4	A5	A6	A7	A8
M	E	K	V	E	Q	H	E
A9	A10	A11	A12	A13	A14	A15	A16
S	T	L	S	V	R	E	G
A17	A18	A19	A20	A21	A22	A23	A24
D	S	A	V	I	N	C	T
A25	A26	A27	A28	A29	A36	A37	A38
Y	T	D	T	A	S	S	Y
A39	A40	A41	A42	A43	A44	A45	A46
F	P	W	Y	K	Q	E	A
A47	A48	A49	A50	A51	A52	A53	A54
G	K	G	L	H	F	V	I
A55	A56	A57	A58	A59	A63	A64	A65
D	I	R	S	N	V	D	R
A66	A67	A68	A74	A75	A76	A77	A78
K	Q	S	Q	R	L	I	V
A79	A80	A81	A82	A83	A84	A85	A86
L	L	D	K	K	A	K	R
A87	A88	A89	A90	A91	A92	A93	A94
F	S	L	H	I	T	A	T
A95	A96	A97	A98	A99	A100	A101	A102
Q	P	E	D	S	A	I	Y
A103	A104	A105	A106	A107	A108	A109	A110
F	C	A	A	S	P	S	N
A111	A111A	A112A	A112	A113	A114	A115	A116
S	G	G	S	N	Y	K	L
A117	A118	A119	A120	A121	A122	A123	A124
T	F	G	K	G	T	L	L
A125	A126	A127	A128
T	V	T	P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	TCSAGLGYEQY	None	11
CDRB2	LRSPGD	B2-6-C	6
CDRB1	NSQYPW	B1-6-A	6
CDRA3	AASPSNSGGSNYKLT	None	15
CDRA2	IRSNVDR	None	7
CDRA1	DTASSY	None	6

Orientation and docking angles:

Angle	Value
BC2	107.29°
BC1	78.06°
BA	-56.66°
AC2	82.85°
AC1	120.36°
dc	15.24Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
3uts_JI	108.87°	79.90°	-58.16°	82.82°	121.85°	15.91Å	3.3
5nmg_ED	107.26°	76.37°	-59.58°	81.55°	120.22°	15.37Å	3.6
3uts_ED	109.15°	79.11°	-59.05°	83.20°	121.82°	15.95Å	3.6
6dfs_BA	108.16°	76.95°	-59.83°	81.45°	120.03°	15.35Å	3.8
5nmg_JI	105.93°	75.84°	-59.97°	82.23°	119.89°	15.38Å	4.3

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	5.3
1mlc_DC	111.18°	74.81°	-53.86°	82.25°	119.71°	16.04Å	5.9
1p2c_ED	111.04°	74.65°	-55.59°	80.59°	117.61°	16.22Å	6.4
3mo1_BA	109.77°	73.00°	-58.46°	81.03°	119.12°	16.26Å	6.4
4yfl_HL	109.78°	73.75°	-56.79°	79.59°	122.71°	16.13Å	6.5

D / C

TCR Details:

Item	Info
VB chain	D
VA chain	C
VB IMGT details	TRBV1/TRBJ2
VA IMGT details	TRAV10/TRAJ53
Species	mouse

Numbered sequence

Chain type

Chain ID

FASTA/Annotation file

IMGT numbered sequence (Framework/CDR)

FASTA file

B1	B2	B3	B4	B5	B6	B7	B8
M	T	L	L	E	Q	N	P
B9	B10	B11	B12	B13	B14	B15	B16
R	W	R	L	V	P	R	G
B17	B18	B19	B20	B21	B22	B23	B24
Q	A	V	N	L	R	C	I
B25	B26	B27	B28	B29	B36	B37	B38
L	K	N	S	Q	Y	P	W
B39	B40	B41	B42	B43	B44	B45	B46
M	S	W	Y	Q	Q	D	L
B47	B48	B49	B50	B51	B52	B53	B54
Q	K	Q	L	Q	W	L	F
B55	B56	B57	B58	B63	B64	B65	B66
T	L	R	S	P	G	D	K
B67	B68	B69	B70	B71	B72	B73	B74
E	V	K	S	L	P	G	A
B75	B76	B77	B78	B79	B80	B81	B83
D	Y	L	A	T	R	V	T
B84	B85	B86	B87	B88	B89	B90	B91
D	T	E	L	R	L	Q	V
B92	B93	B94	B95	B98	B99	B100	B101
A	N	M	S	Q	G	R	T
B102	B103	B104	B105	B106	B107	B108	B109
L	Y	C	T	C	S	A	G
B110	B113	B114	B115	B116	B117	B118	B119
L	G	Y	E	Q	Y	F	G
B120	B121	B122	B123	B124	B125	B126	B127
P	G	T	R	L	T	V	L

FASTA file

A1	A2	A3	A4	A5	A6	A7	A8
M	E	K	V	E	Q	H	E
A9	A10	A11	A12	A13	A14	A15	A16
S	T	L	S	V	R	E	G
A17	A18	A19	A20	A21	A22	A23	A24
D	S	A	V	I	N	C	T
A25	A26	A27	A28	A29	A36	A37	A38
Y	T	D	T	A	S	S	Y
A39	A40	A41	A42	A43	A44	A45	A46
F	P	W	Y	K	Q	E	A
A47	A48	A49	A50	A51	A52	A53	A54
G	K	G	L	H	F	V	I
A55	A56	A57	A58	A59	A63	A64	A65
D	I	R	S	N	V	D	R
A66	A67	A68	A74	A75	A76	A77	A78
K	Q	S	Q	R	L	I	V
A79	A80	A81	A82	A83	A84	A85	A86
L	L	D	K	K	A	K	R
A87	A88	A89	A90	A91	A92	A93	A94
F	S	L	H	I	T	A	T
A95	A96	A97	A98	A99	A100	A101	A102
Q	P	E	D	S	A	I	Y
A103	A104	A105	A106	A107	A108	A109	A110
F	C	A	A	S	P	S	N
A111	A111A	A112A	A112	A113	A114	A115	A116
S	G	G	S	N	Y	K	L
A117	A118	A119	A120	A121	A122	A123	A124
T	F	G	K	G	T	L	L
A125	A126	A127	A128
T	V	T	P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	TCSAGLGYEQY	None	11
CDRB2	LRSPGD	B2-6-C	6
CDRB1	NSQYPW	B1-6-A	6
CDRA3	AASPSNSGGSNYKLT	None	15
CDRA2	IRSNVDR	None	7
CDRA1	DTASSY	None	6

Orientation and docking angles:

Angle	Value
BC2	107.89°
BC1	77.81°
BA	-60.67°
AC2	82.33°
AC1	120.67°
dc	15.36Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
6dfs_BA	108.16°	76.95°	-59.83°	81.45°	120.03°	15.35Å	1.6
5nmg_ED	107.26°	76.37°	-59.58°	81.55°	120.22°	15.37Å	2.1
5nme_ED	106.95°	76.37°	-60.59°	80.74°	120.38°	15.51Å	2.4
3uts_ED	109.15°	79.11°	-59.05°	83.20°	121.82°	15.95Å	2.9
5nmg_JI	105.93°	75.84°	-59.97°	82.23°	119.89°	15.38Å	3.0

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	4.4
1cl7_HL	111.63°	74.67°	-60.00°	82.67°	121.69°	16.39Å	5.1
2dlf_HL	110.76°	78.47°	-60.69°	79.06°	117.44°	15.78Å	5.5
2dbl_HL	110.84°	73.37°	-61.14°	82.14°	120.45°	16.63Å	5.5
3ncy_PS	112.64°	76.63°	-61.62°	81.39°	118.27°	15.77Å	5.6

F / E

TCR Details:

Item	Info
VB chain	F
VA chain	E
VB IMGT details	TRBV1/TRBJ2
VA IMGT details	TRAV10/TRAJ53
Species	mouse

Numbered sequence

Chain type

Chain ID

FASTA/Annotation file

IMGT numbered sequence (Framework/CDR)

FASTA file

B1	B2	B3	B4	B5	B6	B7	B8
M	T	L	L	E	Q	N	P
B9	B10	B11	B12	B13	B14	B15	B16
R	W	R	L	V	P	R	G
B17	B18	B19	B20	B21	B22	B23	B24
Q	A	V	N	L	R	C	I
B25	B26	B27	B28	B29	B36	B37	B38
L	K	N	S	Q	Y	P	W
B39	B40	B41	B42	B43	B44	B45	B46
M	S	W	Y	Q	Q	D	L
B47	B48	B49	B50	B51	B52	B53	B54
Q	K	Q	L	Q	W	L	F
B55	B56	B57	B58	B63	B64	B65	B66
T	L	R	S	P	G	D	K
B67	B68	B69	B70	B71	B72	B73	B74
E	V	K	S	L	P	G	A
B75	B76	B77	B78	B79	B80	B81	B83
D	Y	L	A	T	R	V	T
B84	B85	B86	B87	B88	B89	B90	B91
D	T	E	L	R	L	Q	V
B92	B93	B94	B95	B98	B99	B100	B101
A	N	M	S	Q	G	R	T
B102	B103	B104	B105	B106	B107	B108	B109
L	Y	C	T	C	S	A	G
B110	B113	B114	B115	B116	B117	B118	B119
L	G	Y	E	Q	Y	F	G
B120	B121	B122	B123	B124	B125	B126	B127
P	G	T	R	L	T	V	L

FASTA file

A1	A2	A3	A4	A5	A6	A7	A8
M	E	K	V	E	Q	H	E
A9	A10	A11	A12	A13	A14	A15	A16
S	T	L	S	V	R	E	G
A17	A18	A19	A20	A21	A22	A23	A24
D	S	A	V	I	N	C	T
A25	A26	A27	A28	A29	A36	A37	A38
Y	T	D	T	A	S	S	Y
A39	A40	A41	A42	A43	A44	A45	A46
F	P	W	Y	K	Q	E	A
A47	A48	A49	A50	A51	A52	A53	A54
G	K	G	L	H	F	V	I
A55	A56	A57	A58	A59	A63	A64	A65
D	I	R	S	N	V	D	R
A66	A67	A68	A74	A75	A76	A77	A78
K	Q	S	Q	R	L	I	V
A79	A80	A81	A82	A83	A84	A85	A86
L	L	D	K	K	A	K	R
A87	A88	A89	A90	A91	A92	A93	A94
F	S	L	H	I	T	A	T
A95	A96	A97	A98	A99	A100	A101	A102
Q	P	E	D	S	A	I	Y
A103	A104	A105	A106	A107	A108	A109	A110
F	C	A	A	S	P	S	N
A111	A111A	A112A	A112	A113	A114	A115	A116
S	G	G	S	N	Y	K	L
A117	A118	A119	A120	A121	A122	A123	A124
T	F	G	K	G	T	L	L
A125	A126	A127	A128
T	V	T	P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	TCSAGLGYEQY	None	11
CDRB2	LRSPGD	B2-6-C	6
CDRB1	NSQYPW	B1-6-A	6
CDRA3	AASPSNSGGSNYKLT	None	15
CDRA2	IRSNVDR	None	7
CDRA1	DTASSY	None	6

Orientation and docking angles:

Angle	Value
BC2	106.35°
BC1	79.02°
BA	-57.24°
AC2	81.44°
AC1	120.30°
dc	15.27Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
3uts_JI	108.87°	79.90°	-58.16°	82.82°	121.85°	15.91Å	3.6
5nmg_ED	107.26°	76.37°	-59.58°	81.55°	120.22°	15.37Å	3.7
6dfs_BA	108.16°	76.95°	-59.83°	81.45°	120.03°	15.35Å	3.8
3uts_ED	109.15°	79.11°	-59.05°	83.20°	121.82°	15.95Å	4.1
5nmg_JI	105.93°	75.84°	-59.97°	82.23°	119.89°	15.38Å	4.3

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	5.0
2dlf_HL	110.76°	78.47°	-60.69°	79.06°	117.44°	15.78Å	6.8
4yfl_HL	109.78°	73.75°	-56.79°	79.59°	122.71°	16.13Å	7.1
3mo1_BA	109.77°	73.00°	-58.46°	81.03°	119.12°	16.26Å	7.2
1p2c_ED	111.04°	74.65°	-55.59°	80.59°	117.61°	16.22Å	7.3

H / G

TCR Details:

Item	Info
VB chain	H
VA chain	G
VB IMGT details	TRBV1/TRBJ2
VA IMGT details	TRAV10/TRAJ53
Species	mouse

Numbered sequence

Chain type

Chain ID

FASTA/Annotation file

IMGT numbered sequence (Framework/CDR)

FASTA file

B1	B2	B3	B4	B5	B6	B7	B8
M	T	L	L	E	Q	N	P
B9	B10	B11	B12	B13	B14	B15	B16
R	W	R	L	V	P	R	G
B17	B18	B19	B20	B21	B22	B23	B24
Q	A	V	N	L	R	C	I
B25	B26	B27	B28	B29	B36	B37	B38
L	K	N	S	Q	Y	P	W
B39	B40	B41	B42	B43	B44	B45	B46
M	S	W	Y	Q	Q	D	L
B47	B48	B49	B50	B51	B52	B53	B54
Q	K	Q	L	Q	W	L	F
B55	B56	B57	B58	B63	B64	B65	B66
T	L	R	S	P	G	D	K
B67	B68	B69	B70	B71	B72	B73	B74
E	V	K	S	L	P	G	A
B75	B76	B77	B78	B79	B80	B81	B83
D	Y	L	A	T	R	V	T
B84	B85	B86	B87	B88	B89	B90	B91
D	T	E	L	R	L	Q	V
B92	B93	B94	B95	B98	B99	B100	B101
A	N	M	S	Q	G	R	T
B102	B103	B104	B105	B106	B107	B108	B109
L	Y	C	T	C	S	A	G
B110	B113	B114	B115	B116	B117	B118	B119
L	G	Y	E	Q	Y	F	G
B120	B121	B122	B123	B124	B125	B126	B127
P	G	T	R	L	T	V	L

FASTA file

A1	A2	A3	A4	A5	A6	A7	A8
M	E	K	V	E	Q	H	E
A9	A10	A11	A12	A13	A14	A15	A16
S	T	L	S	V	R	E	G
A17	A18	A19	A20	A21	A22	A23	A24
D	S	A	V	I	N	C	T
A25	A26	A27	A28	A29	A36	A37	A38
Y	T	D	T	A	S	S	Y
A39	A40	A41	A42	A43	A44	A45	A46
F	P	W	Y	K	Q	E	A
A47	A48	A49	A50	A51	A52	A53	A54
G	K	G	L	H	F	V	I
A55	A56	A57	A58	A59	A63	A64	A65
D	I	R	S	N	V	D	R
A66	A67	A68	A74	A75	A76	A77	A78
K	Q	S	Q	R	L	I	V
A79	A80	A81	A82	A83	A84	A85	A86
L	L	D	K	K	A	K	R
A87	A88	A89	A90	A91	A92	A93	A94
F	S	L	H	I	T	A	T
A95	A96	A97	A98	A99	A100	A101	A102
Q	P	E	D	S	A	I	Y
A103	A104	A105	A106	A107	A108	A109	A110
F	C	A	A	S	P	S	N
A111	A111A	A112A	A112	A113	A114	A115	A116
S	G	G	S	N	Y	K	L
A117	A118	A119	A120	A121	A122	A123	A124
T	F	G	K	G	T	L	L
A125	A126	A127	A128
T	V	T	P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	TCSAGLGYEQY	None	11
CDRB2	LRSPGD	B2-6-C	6
CDRB1	NSQYPW	B1-6-A	6
CDRA3	AASPSNSGGSNYKLT	None	15
CDRA2	IRSNVDR	None	7
CDRA1	DTASSY	None	6

Orientation and docking angles:

Angle	Value
BC2	106.37°
BC1	78.88°
BA	-59.70°
AC2	82.62°
AC1	121.42°
dc	15.08Å

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
1nam_BA	106.13°	79.79°	-59.22°	84.36°	122.75°	15.08Å	2.4
5nmg_ED	107.26°	76.37°	-59.58°	81.55°	120.22°	15.37Å	3.1
3uts_ED	109.15°	79.11°	-59.05°	83.20°	121.82°	15.95Å	3.1
6dfs_BA	108.16°	76.95°	-59.83°	81.45°	120.03°	15.35Å	3.2
3uts_JI	108.87°	79.90°	-58.16°	82.82°	121.85°	15.91Å	3.3

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	5.7
1cl7_HL	111.63°	74.67°	-60.00°	82.67°	121.69°	16.39Å	6.9
2dlf_HL	110.76°	78.47°	-60.69°	79.06°	117.44°	15.78Å	7.0
2dbl_HL	110.84°	73.37°	-61.14°	82.14°	120.45°	16.63Å	7.5
3mo1_BA	109.77°	73.00°	-58.46°	81.03°	119.12°	16.26Å	7.5

Available downloads

Additional links and files for download: see help for more details.

Item	Link
IMGT-numbered structure	Link
Non-annotated structure from the PDB	Link
Summary file for this TCR	Link
Link in the PDB	Link