About STCRPred

Information about the database, and overview of TCRs.

  • STCRPred is a site reserved for T-cell receptor structural modelling. Currently, we only host the canonical form prediction tool for the complementarity determining regions.
  • STCRPred has been built by the Oxford Protein Informatics Group (OPIG).
Input To predict the canonical forms for T-cell receptor sequences
  1. Go to the Canonical form prediction page.
  2. Paste a single amino-acid sequence into the text box or upload multiple sequences in a fasta file.
  3. If you want to annotate the heavy and light chains, submit the sequences separated by '/'.
  4. Click "Submit".
Process
  • The SCALOP algorithm will first number the input sequences using ANARCI, and extract the CDR sequences.
  • The CDR sequences are then scored against the matrices for the corresponding CDR clusters.
  • The sequences are then assigned to the cluster with the maximum score.
Output
  • The assigned clusters for each CDR (except B3) are displayed along with the PDB code and chain identifier from which the median structures of the assigned clusters were extracted.
  • The assignment result is downloaded automatically.
  • When multiple sequences are uploaded, the assignment result for each sequence is shown.
  • Where no result is shown for a given sequence, it is not considered an antibody by ANARCI, thus no assignment is made.
  • Feel free to contact us at for any issues or general enquiries about STCRPred.