STCRPred is a site reserved for T-cell receptor structural modelling. Currently, we only host the canonical form prediction tool for the complementarity determining regions.
STCRPred has been built by the Oxford Protein Informatics Group (OPIG).
Paste a single amino-acid sequence into the text box or upload multiple sequences in a fasta file.
If you want to annotate the heavy and light chains, submit the sequences separated by '/'.
Click "Submit".
Process
The SCALOP algorithm will first number the input sequences using ANARCI, and extract the CDR sequences.
The CDR sequences are then scored against the matrices for the corresponding CDR clusters.
The sequences are then assigned to the cluster with the maximum score.
Output
The assigned clusters for each CDR (except B3) are displayed along with the PDB code and chain identifier from which the median structures of the assigned clusters were extracted.
The assignment result is downloaded automatically.
When multiple sequences are uploaded, the assignment result for each sequence is shown.
Where no result is shown for a given sequence, it is not considered an antibody by ANARCI, thus no assignment is made.
for any issues or general enquiries about STCRPred.