Antibodies are products of immune systems that bind pathogens with high specificity, thus making them the most successful class of biopharmaceuticals. Successful exploitation of antibodies relies on our ability to interrogate their diversity. My DPhil project is on investigation of antibody next-generation sequencing (Ig-seq) data to inform rational antibody engineering. Application space of Ig-seq data is very vast. I am particularly interested in contrasting Ig-seq datasets across and within various species. This can ultimately lead to a set of rules that govern antibody development in respective species. This work is in close collaboration with UCB Pharma via the DTP iCASE scheme.