data_7A6O
# 
_entry.id   7A6O 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.338 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
PDB   7A6O         
WWPDB D_1292110926 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7A6O 
_pdbx_database_status.recvd_initial_deposition_date   2020-08-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Brown, A.K.' 1 0000-0002-2154-4280 
'Emsley, J.'  2 0000-0002-8949-8030 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Nicholas, A.A.' 1 ? 
primary 'Wenpeng, C.'    2 ? 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7A6O 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     65.234 
_cell.length_a_esd                 ? 
_cell.length_b                     65.234 
_cell.length_b_esd                 ? 
_cell.length_c                     233.231 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         7A6O 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                96 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 43 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'von Willebrand factor'   23447.203 1   ? ? ? ? 
2 polymer     man 'VHH81 Nanobody fragment' 13856.432 1   ? ? ? ? 
3 non-polymer syn 'SULFATE ION'             96.063    1   ? ? ? ? 
4 water       nat water                     18.015    160 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;ISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRKRPSELR
RIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRIALLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHAN
LKQIRLIEKQAPENKAFVLSSVDELEQQRDEIVSYLCDLAPEAPP
;
;ISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRKRPSELR
RIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRIALLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHAN
LKQIRLIEKQAPENKAFVLSSVDELEQQRDEIVSYLCDLAPEAPP
;
AAA ? 
2 'polypeptide(L)' no no 
;EVQLVESGGGLVQPGGSLRLSCAASGRTFSYNPMGWFRQAPGKGRELVAAISRTGGSTYYPDSVEGRFTISRDNAKRMVY
LQMNSLRAEDTAVYYCAAAGVRAEDGRVRTLPSEYTFWGQGTQVTVSS
;
;EVQLVESGGGLVQPGGSLRLSCAASGRTFSYNPMGWFRQAPGKGRELVAAISRTGGSTYYPDSVEGRFTISRDNAKRMVY
LQMNSLRAEDTAVYYCAAAGVRAEDGRVRTLPSEYTFWGQGTQVTVSS
;
BBB ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ILE n 
1 2   SER n 
1 3   GLU n 
1 4   PRO n 
1 5   PRO n 
1 6   LEU n 
1 7   HIS n 
1 8   ASP n 
1 9   PHE n 
1 10  TYR n 
1 11  CYS n 
1 12  SER n 
1 13  ARG n 
1 14  LEU n 
1 15  LEU n 
1 16  ASP n 
1 17  LEU n 
1 18  VAL n 
1 19  PHE n 
1 20  LEU n 
1 21  LEU n 
1 22  ASP n 
1 23  GLY n 
1 24  SER n 
1 25  SER n 
1 26  ARG n 
1 27  LEU n 
1 28  SER n 
1 29  GLU n 
1 30  ALA n 
1 31  GLU n 
1 32  PHE n 
1 33  GLU n 
1 34  VAL n 
1 35  LEU n 
1 36  LYS n 
1 37  ALA n 
1 38  PHE n 
1 39  VAL n 
1 40  VAL n 
1 41  ASP n 
1 42  MET n 
1 43  MET n 
1 44  GLU n 
1 45  ARG n 
1 46  LEU n 
1 47  ARG n 
1 48  ILE n 
1 49  SER n 
1 50  GLN n 
1 51  LYS n 
1 52  TRP n 
1 53  VAL n 
1 54  ARG n 
1 55  VAL n 
1 56  ALA n 
1 57  VAL n 
1 58  VAL n 
1 59  GLU n 
1 60  TYR n 
1 61  HIS n 
1 62  ASP n 
1 63  GLY n 
1 64  SER n 
1 65  HIS n 
1 66  ALA n 
1 67  TYR n 
1 68  ILE n 
1 69  GLY n 
1 70  LEU n 
1 71  LYS n 
1 72  ASP n 
1 73  ARG n 
1 74  LYS n 
1 75  ARG n 
1 76  PRO n 
1 77  SER n 
1 78  GLU n 
1 79  LEU n 
1 80  ARG n 
1 81  ARG n 
1 82  ILE n 
1 83  ALA n 
1 84  SER n 
1 85  GLN n 
1 86  VAL n 
1 87  LYS n 
1 88  TYR n 
1 89  ALA n 
1 90  GLY n 
1 91  SER n 
1 92  GLN n 
1 93  VAL n 
1 94  ALA n 
1 95  SER n 
1 96  THR n 
1 97  SER n 
1 98  GLU n 
1 99  VAL n 
1 100 LEU n 
1 101 LYS n 
1 102 TYR n 
1 103 THR n 
1 104 LEU n 
1 105 PHE n 
1 106 GLN n 
1 107 ILE n 
1 108 PHE n 
1 109 SER n 
1 110 LYS n 
1 111 ILE n 
1 112 ASP n 
1 113 ARG n 
1 114 PRO n 
1 115 GLU n 
1 116 ALA n 
1 117 SER n 
1 118 ARG n 
1 119 ILE n 
1 120 ALA n 
1 121 LEU n 
1 122 LEU n 
1 123 LEU n 
1 124 MET n 
1 125 ALA n 
1 126 SER n 
1 127 GLN n 
1 128 GLU n 
1 129 PRO n 
1 130 GLN n 
1 131 ARG n 
1 132 MET n 
1 133 SER n 
1 134 ARG n 
1 135 ASN n 
1 136 PHE n 
1 137 VAL n 
1 138 ARG n 
1 139 TYR n 
1 140 VAL n 
1 141 GLN n 
1 142 GLY n 
1 143 LEU n 
1 144 LYS n 
1 145 LYS n 
1 146 LYS n 
1 147 LYS n 
1 148 VAL n 
1 149 ILE n 
1 150 VAL n 
1 151 ILE n 
1 152 PRO n 
1 153 VAL n 
1 154 GLY n 
1 155 ILE n 
1 156 GLY n 
1 157 PRO n 
1 158 HIS n 
1 159 ALA n 
1 160 ASN n 
1 161 LEU n 
1 162 LYS n 
1 163 GLN n 
1 164 ILE n 
1 165 ARG n 
1 166 LEU n 
1 167 ILE n 
1 168 GLU n 
1 169 LYS n 
1 170 GLN n 
1 171 ALA n 
1 172 PRO n 
1 173 GLU n 
1 174 ASN n 
1 175 LYS n 
1 176 ALA n 
1 177 PHE n 
1 178 VAL n 
1 179 LEU n 
1 180 SER n 
1 181 SER n 
1 182 VAL n 
1 183 ASP n 
1 184 GLU n 
1 185 LEU n 
1 186 GLU n 
1 187 GLN n 
1 188 GLN n 
1 189 ARG n 
1 190 ASP n 
1 191 GLU n 
1 192 ILE n 
1 193 VAL n 
1 194 SER n 
1 195 TYR n 
1 196 LEU n 
1 197 CYS n 
1 198 ASP n 
1 199 LEU n 
1 200 ALA n 
1 201 PRO n 
1 202 GLU n 
1 203 ALA n 
1 204 PRO n 
1 205 PRO n 
2 1   GLU n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLU n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  LEU n 
2 12  VAL n 
2 13  GLN n 
2 14  PRO n 
2 15  GLY n 
2 16  GLY n 
2 17  SER n 
2 18  LEU n 
2 19  ARG n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  ALA n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  ARG n 
2 28  THR n 
2 29  PHE n 
2 30  SER n 
2 31  TYR n 
2 32  ASN n 
2 33  PRO n 
2 34  MET n 
2 35  GLY n 
2 36  TRP n 
2 37  PHE n 
2 38  ARG n 
2 39  GLN n 
2 40  ALA n 
2 41  PRO n 
2 42  GLY n 
2 43  LYS n 
2 44  GLY n 
2 45  ARG n 
2 46  GLU n 
2 47  LEU n 
2 48  VAL n 
2 49  ALA n 
2 50  ALA n 
2 51  ILE n 
2 52  SER n 
2 53  ARG n 
2 54  THR n 
2 55  GLY n 
2 56  GLY n 
2 57  SER n 
2 58  THR n 
2 59  TYR n 
2 60  TYR n 
2 61  PRO n 
2 62  ASP n 
2 63  SER n 
2 64  VAL n 
2 65  GLU n 
2 66  GLY n 
2 67  ARG n 
2 68  PHE n 
2 69  THR n 
2 70  ILE n 
2 71  SER n 
2 72  ARG n 
2 73  ASP n 
2 74  ASN n 
2 75  ALA n 
2 76  LYS n 
2 77  ARG n 
2 78  MET n 
2 79  VAL n 
2 80  TYR n 
2 81  LEU n 
2 82  GLN n 
2 83  MET n 
2 84  ASN n 
2 85  SER n 
2 86  LEU n 
2 87  ARG n 
2 88  ALA n 
2 89  GLU n 
2 90  ASP n 
2 91  THR n 
2 92  ALA n 
2 93  VAL n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  ALA n 
2 98  ALA n 
2 99  ALA n 
2 100 GLY n 
2 101 VAL n 
2 102 ARG n 
2 103 ALA n 
2 104 GLU n 
2 105 ASP n 
2 106 GLY n 
2 107 ARG n 
2 108 VAL n 
2 109 ARG n 
2 110 THR n 
2 111 LEU n 
2 112 PRO n 
2 113 SER n 
2 114 GLU n 
2 115 TYR n 
2 116 THR n 
2 117 PHE n 
2 118 TRP n 
2 119 GLY n 
2 120 GLN n 
2 121 GLY n 
2 122 THR n 
2 123 GLN n 
2 124 VAL n 
2 125 THR n 
2 126 VAL n 
2 127 SER n 
2 128 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 205 Human ? VWF ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? 
? ? Expi293F     ? ? ? ? ? ? ? ? ? ? ? pET22b+     ? ? 
2 1 sample 'Biological sequence' 1 128 ?     ? VHH ? ? ? ? ? ? 'Lama glama'   9844 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  ? ? ? ? 
? ? 'SHuffle T7' ? ? ? ? ? ? ? ? ? ? ? 'pET22b(+)' ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP L8E853_HUMAN L8E853 ? 1 
;ISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRKRPSELR
RIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRIALLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHAN
LKQIRLIEKQAPENKAFVLSSVDELEQQRDEIVSYLCDLAPEAPP
;
1262 
2 PDB 7A6O         7A6O   ? 2 ? 1    
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7A6O AAA 1 ? 205 ? L8E853 1262 ? 1466 ? 1262 1466 
2 2 7A6O BBB 1 ? 128 ? 7A6O   2    ? 129  ? 2    129  
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7A6O 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                      ? 
_exptl_crystal.density_diffrn              ? 
_exptl_crystal.density_Matthews            3.32 
_exptl_crystal.density_method              ? 
_exptl_crystal.density_percent_sol         62.98 
_exptl_crystal.description                 ? 
_exptl_crystal.F_000                       ? 
_exptl_crystal.id                          1 
_exptl_crystal.preparation                 ? 
_exptl_crystal.size_max                    ? 
_exptl_crystal.size_mid                    ? 
_exptl_crystal.size_min                    ? 
_exptl_crystal.size_rad                    ? 
_exptl_crystal.colour_lustre               ? 
_exptl_crystal.colour_modifier             ? 
_exptl_crystal.colour_primary              ? 
_exptl_crystal.density_meas                ? 
_exptl_crystal.density_meas_esd            ? 
_exptl_crystal.density_meas_gt             ? 
_exptl_crystal.density_meas_lt             ? 
_exptl_crystal.density_meas_temp           ? 
_exptl_crystal.density_meas_temp_esd       ? 
_exptl_crystal.density_meas_temp_gt        ? 
_exptl_crystal.density_meas_temp_lt        ? 
_exptl_crystal.pdbx_crystal_image_url      ? 
_exptl_crystal.pdbx_crystal_image_format   ? 
_exptl_crystal.pdbx_mosaicity              ? 
_exptl_crystal.pdbx_mosaicity_esd          ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.2 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp            283 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '3.2 M ammonium sulphate, 0.08 M sodium citrate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     283 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-15 
_diffrn_detector.pdbx_frequency               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9795 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I04' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9795 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I04 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate            ? 
_reflns.entry_id                         7A6O 
_reflns.data_reduction_details           ? 
_reflns.data_reduction_method            ? 
_reflns.d_resolution_high                2.1 
_reflns.d_resolution_low                 62.9 
_reflns.details                          ? 
_reflns.limit_h_max                      ? 
_reflns.limit_h_min                      ? 
_reflns.limit_k_max                      ? 
_reflns.limit_k_min                      ? 
_reflns.limit_l_max                      ? 
_reflns.limit_l_min                      ? 
_reflns.number_all                       ? 
_reflns.number_obs                       19344 
_reflns.observed_criterion               ? 
_reflns.observed_criterion_F_max         ? 
_reflns.observed_criterion_F_min         ? 
_reflns.observed_criterion_I_max         ? 
_reflns.observed_criterion_I_min         ? 
_reflns.observed_criterion_sigma_F       ? 
_reflns.observed_criterion_sigma_I       ? 
_reflns.percent_possible_obs             92.4 
_reflns.R_free_details                   ? 
_reflns.Rmerge_F_all                     ? 
_reflns.Rmerge_F_obs                     ? 
_reflns.Friedel_coverage                 ? 
_reflns.number_gt                        ? 
_reflns.threshold_expression             ? 
_reflns.pdbx_redundancy                  5.2 
_reflns.pdbx_Rmerge_I_obs                0.048 
_reflns.pdbx_Rmerge_I_all                ? 
_reflns.pdbx_Rsym_value                  ? 
_reflns.pdbx_netI_over_av_sigmaI         ? 
_reflns.pdbx_netI_over_sigmaI            15.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2   ? 
_reflns.pdbx_res_netI_over_sigmaI_2      ? 
_reflns.pdbx_chi_squared                 ? 
_reflns.pdbx_scaling_rejects             ? 
_reflns.pdbx_d_res_high_opt              ? 
_reflns.pdbx_d_res_low_opt               ? 
_reflns.pdbx_d_res_opt_method            ? 
_reflns.phase_calculation_details        ? 
_reflns.pdbx_Rrim_I_all                  ? 
_reflns.pdbx_Rpim_I_all                  ? 
_reflns.pdbx_d_opt                       ? 
_reflns.pdbx_number_measured_all         ? 
_reflns.pdbx_diffrn_id                   1 
_reflns.pdbx_ordinal                     1 
_reflns.pdbx_CC_half                     1.0 
_reflns.pdbx_CC_star                     ? 
_reflns.pdbx_R_split                     ? 
# 
_reflns_shell.d_res_high                  2.1 
_reflns_shell.d_res_low                   2.3 
_reflns_shell.meanI_over_sigI_all         ? 
_reflns_shell.meanI_over_sigI_obs         1.7 
_reflns_shell.number_measured_all         ? 
_reflns_shell.number_measured_obs         ? 
_reflns_shell.number_possible             ? 
_reflns_shell.number_unique_all           ? 
_reflns_shell.number_unique_obs           2527 
_reflns_shell.percent_possible_all        69.2 
_reflns_shell.percent_possible_obs        ? 
_reflns_shell.Rmerge_F_all                ? 
_reflns_shell.Rmerge_F_obs                ? 
_reflns_shell.Rmerge_I_all                ? 
_reflns_shell.Rmerge_I_obs                0.645 
_reflns_shell.meanI_over_sigI_gt          ? 
_reflns_shell.meanI_over_uI_all           ? 
_reflns_shell.meanI_over_uI_gt            ? 
_reflns_shell.number_measured_gt          ? 
_reflns_shell.number_unique_gt            ? 
_reflns_shell.percent_possible_gt         ? 
_reflns_shell.Rmerge_F_gt                 ? 
_reflns_shell.Rmerge_I_gt                 ? 
_reflns_shell.pdbx_redundancy             ? 
_reflns_shell.pdbx_Rsym_value             ? 
_reflns_shell.pdbx_chi_squared            ? 
_reflns_shell.pdbx_netI_over_sigmaI_all   ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs   ? 
_reflns_shell.pdbx_Rrim_I_all             ? 
_reflns_shell.pdbx_Rpim_I_all             ? 
_reflns_shell.pdbx_rejects                ? 
_reflns_shell.pdbx_ordinal                1 
_reflns_shell.pdbx_diffrn_id              1 
_reflns_shell.pdbx_CC_half                0.6 
_reflns_shell.pdbx_CC_star                ? 
_reflns_shell.pdbx_R_split                ? 
# 
_refine.aniso_B[1][1]                            -0.155 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            -0.155 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.310 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               51.291 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.959 
_refine.correlation_coeff_Fo_to_Fc_free          0.916 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 7A6O 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.1 
_refine.ls_d_res_low                             62.8 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     19344 
_refine.ls_number_reflns_R_free                  921 
_refine.ls_number_reflns_R_work                  18423 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    92.4 
_refine.ls_percent_reflns_R_free                 4.761 
_refine.ls_R_factor_all                          0.198 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2558 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1947 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      1AUQ 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.300 
_refine.pdbx_overall_ESU_R_Free                  0.247 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.1 
_refine_hist.d_res_low                        62.8 
_refine_hist.number_atoms_solvent             160 
_refine_hist.number_atoms_total               2785 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2620 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         5 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.013  2683 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.035  0.017  2540 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.727  1.645  3626 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 2.339  1.575  5873 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 7.550  5.000  333  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 26.913 20.333 150  ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.499 15.000 473  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 20.867 15.000 28   ? r_dihedral_angle_4_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.070  0.200  337  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  3002 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.011  0.020  598  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.211  0.200  494  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.220  0.200  2427 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.162  0.200  1229 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.073  0.200  1251 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.191  0.200  131  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.133  0.200  2    ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.569  0.200  3    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.154  0.200  18   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.387  0.200  9    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 0.278  0.200  1    ? r_xyhbond_nbd_other            ? ? 
'X-RAY DIFFRACTION' ? 4.265  5.161  1332 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.265  5.157  1331 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 5.937  7.724  1662 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.935  7.728  1663 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.244  5.662  1351 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.211  5.652  1347 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 7.914  8.279  1963 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.880  8.264  1958 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 24.822 60.260 2883 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 24.864 60.048 2862 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
'X-RAY DIFFRACTION' 2.117 2.172 . . 1  30   1.4372  . . . 0.648 . 0.449 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.172 2.231 . . 12 224  11.4065 . . . 0.537 . 0.376 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.231 2.296 . . 22 397  20.4490 . . . 0.308 . 0.299 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.296 2.367 . . 28 522  27.6104 . . . 0.423 . 0.306 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.367 2.444 . . 23 640  34.4774 . . . 0.296 . 0.274 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.444 2.530 . . 35 811  44.9522 . . . 0.296 . 0.249 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.530 2.626 . . 48 1062 61.2245 . . . 0.337 . 0.270 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.626 2.733 . . 56 1441 85.6407 . . . 0.327 . 0.269 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.733 2.854 . . 78 1561 97.6758 . . . 0.348 . 0.249 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.854 2.994 . . 77 1527 99.3804 . . . 0.308 . 0.250 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 2.994 3.156 . . 81 1427 99.2105 . . . 0.287 . 0.240 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.156 3.347 . . 74 1380 99.1138 . . . 0.265 . 0.233 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.347 3.578 . . 66 1306 98.9185 . . . 0.306 . 0.223 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.578 3.865 . . 63 1217 98.5373 . . . 0.298 . 0.206 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.865 4.233 . . 65 1099 98.0623 . . . 0.230 . 0.169 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 4.233 4.733 . . 46 1045 99.1818 . . . 0.178 . 0.127 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 4.733 5.465 . . 51 918  99.1812 . . . 0.167 . 0.130 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 5.465 6.692 . . 48 793  99.2916 . . . 0.208 . 0.159 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 6.692 9.460 . . 31 634  98.3728 . . . 0.256 . 0.161 . . . . . . . . . . . 
# 
_struct.entry_id                     7A6O 
_struct.title                        
'Crystal Structure of the Complex of the Recombinant Von Willebrand Factor AIM-A1 domain and VHH81 at 2.1 Angstrom resolution' 
_struct.pdbx_descriptor              'von Willebrand factor, VHH81 Nanobody fragment' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7A6O 
_struct_keywords.text            'Thrombosis Von Willebrand Factor A1 Aim-A1 Blood Clotting Complex VWF, BLOOD CLOTTING' 
_struct_keywords.pdbx_keywords   'BLOOD CLOTTING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 28  ? ARG A 45  ? SER AAA 1289 ARG AAA 1306 1 ? 18 
HELX_P HELX_P2  AA2 ARG A 75  ? GLN A 85  ? ARG AAA 1336 GLN AAA 1346 1 ? 11 
HELX_P HELX_P3  AA3 SER A 95  ? GLN A 106 ? SER AAA 1356 GLN AAA 1367 1 ? 12 
HELX_P HELX_P4  AA4 PRO A 129 ? ARG A 134 ? PRO AAA 1390 ARG AAA 1395 5 ? 6  
HELX_P HELX_P5  AA5 ASN A 135 ? LYS A 146 ? ASN AAA 1396 LYS AAA 1407 1 ? 12 
HELX_P HELX_P6  AA6 ASN A 160 ? GLN A 170 ? ASN AAA 1421 GLN AAA 1431 1 ? 11 
HELX_P HELX_P7  AA7 VAL A 182 ? LEU A 199 ? VAL AAA 1443 LEU AAA 1460 1 ? 18 
HELX_P HELX_P8  AA8 PRO B 61  ? GLU B 65  ? PRO BBB 62   GLU BBB 66   5 ? 5  
HELX_P HELX_P9  AA9 ASN B 74  ? LYS B 76  ? ASN BBB 75   LYS BBB 77   5 ? 3  
HELX_P HELX_P10 AB1 ARG B 87  ? THR B 91  ? ARG BBB 88   THR BBB 92   5 ? 5  
HELX_P HELX_P11 AB2 LEU B 111 ? SER B 113 ? LEU BBB 112  SER BBB 114  5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 11 SG ? ? ? 1_555 A CYS 197 SG ? ? AAA CYS 1272 AAA CYS 1458 1_555 ? ? ? ? ? ? ? 2.133 ? ? 
disulf2 disulf ? ? B CYS 22 SG ? ? ? 1_555 B CYS 96  SG ? ? BBB CYS 23   BBB CYS 97   1_555 ? ? ? ? ? ? ? 2.130 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 64  ? ILE A 68  ? SER AAA 1325 ILE AAA 1329 
AA1 2 VAL A 53  ? TYR A 60  ? VAL AAA 1314 TYR AAA 1321 
AA1 3 LEU A 15  ? ASP A 22  ? LEU AAA 1276 ASP AAA 1283 
AA1 4 SER A 117 ? MET A 124 ? SER AAA 1378 MET AAA 1385 
AA1 5 VAL A 148 ? ILE A 155 ? VAL AAA 1409 ILE AAA 1416 
AA1 6 PHE A 177 ? LEU A 179 ? PHE AAA 1438 LEU AAA 1440 
AA2 1 GLN B 3   ? SER B 7   ? GLN BBB 4    SER BBB 8    
AA2 2 LEU B 18  ? SER B 25  ? LEU BBB 19   SER BBB 26   
AA2 3 MET B 78  ? MET B 83  ? MET BBB 79   MET BBB 84   
AA2 4 PHE B 68  ? ASP B 73  ? PHE BBB 69   ASP BBB 74   
AA3 1 GLY B 10  ? VAL B 12  ? GLY BBB 11   VAL BBB 13   
AA3 2 THR B 122 ? VAL B 126 ? THR BBB 123  VAL BBB 127  
AA3 3 ALA B 92  ? ALA B 99  ? ALA BBB 93   ALA BBB 100  
AA3 4 MET B 34  ? GLN B 39  ? MET BBB 35   GLN BBB 40   
AA3 5 ARG B 45  ? ILE B 51  ? ARG BBB 46   ILE BBB 52   
AA3 6 THR B 58  ? TYR B 59  ? THR BBB 59   TYR BBB 60   
AA4 1 GLY B 10  ? VAL B 12  ? GLY BBB 11   VAL BBB 13   
AA4 2 THR B 122 ? VAL B 126 ? THR BBB 123  VAL BBB 127  
AA4 3 ALA B 92  ? ALA B 99  ? ALA BBB 93   ALA BBB 100  
AA4 4 TYR B 115 ? TRP B 118 ? TYR BBB 116  TRP BBB 119  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O HIS A 65  ? O HIS AAA 1326 N GLU A 59  ? N GLU AAA 1320 
AA1 2 3 O ARG A 54  ? O ARG AAA 1315 N LEU A 17  ? N LEU AAA 1278 
AA1 3 4 N VAL A 18  ? N VAL AAA 1279 O LEU A 121 ? O LEU AAA 1382 
AA1 4 5 N MET A 124 ? N MET AAA 1385 O ILE A 155 ? O ILE AAA 1416 
AA1 5 6 N GLY A 154 ? N GLY AAA 1415 O LEU A 179 ? O LEU AAA 1440 
AA2 1 2 N GLN B 3   ? N GLN BBB 4    O SER B 25  ? O SER BBB 26   
AA2 2 3 N LEU B 18  ? N LEU BBB 19   O MET B 83  ? O MET BBB 84   
AA2 3 4 O GLN B 82  ? O GLN BBB 83   N THR B 69  ? N THR BBB 70   
AA3 1 2 N VAL B 12  ? N VAL BBB 13   O THR B 125 ? O THR BBB 126  
AA3 2 3 O THR B 122 ? O THR BBB 123  N TYR B 94  ? N TYR BBB 95   
AA3 3 4 O TYR B 95  ? O TYR BBB 96   N PHE B 37  ? N PHE BBB 38   
AA3 4 5 N ARG B 38  ? N ARG BBB 39   O GLU B 46  ? O GLU BBB 47   
AA3 5 6 N ALA B 50  ? N ALA BBB 51   O TYR B 59  ? O TYR BBB 60   
AA4 1 2 N VAL B 12  ? N VAL BBB 13   O THR B 125 ? O THR BBB 126  
AA4 2 3 O THR B 122 ? O THR BBB 123  N TYR B 94  ? N TYR BBB 95   
AA4 3 4 N ALA B 98  ? N ALA BBB 99   O THR B 116 ? O THR BBB 117  
# 
_atom_sites.entry_id                    7A6O 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   0.015329 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015329 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004288 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 2.310  20.844 1.020 10.208 1.589 0.569  0.865 51.651 0.216   
H 0.493  10.511 0.323 26.126 0.140 3.142  0.041 57.800 0.003   
N 12.222 0.006  3.135 9.893  2.014 28.997 1.167 0.583  -11.538 
O 3.049  13.277 2.287 5.701  1.546 0.324  0.867 32.909 0.251   
S 6.905  1.468  5.203 22.215 1.438 0.254  1.586 56.172 1.049   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ILE A 1 1   ? -8.705  3.408   39.856 1.000 119.920 ? 1262 ILE AAA N    1 
ATOM   2    C CA   . ILE A 1 1   ? -8.573  4.794   39.291 1.000 119.110 ? 1262 ILE AAA CA   1 
ATOM   3    C C    . ILE A 1 1   ? -9.986  5.433   39.286 1.000 120.820 ? 1262 ILE AAA C    1 
ATOM   4    O O    . ILE A 1 1   ? -10.510 5.713   40.397 1.000 107.240 ? 1262 ILE AAA O    1 
ATOM   5    C CB   . ILE A 1 1   ? -7.858  4.766   37.905 1.000 109.440 ? 1262 ILE AAA CB   1 
ATOM   6    C CG1  . ILE A 1 1   ? -6.630  3.844   37.878 1.000 89.440  ? 1262 ILE AAA CG1  1 
ATOM   7    C CG2  . ILE A 1 1   ? -7.504  6.176   37.418 1.000 103.150 ? 1262 ILE AAA CG2  1 
ATOM   8    C CD1  . ILE A 1 1   ? -6.276  3.358   36.488 1.000 85.340  ? 1262 ILE AAA CD1  1 
ATOM   9    H H1   . ILE A 1 1   ? -8.428  2.800   39.237 1.000 119.920 ? 1262 ILE AAA H1   1 
ATOM   10   H H2   . ILE A 1 1   ? -9.623  3.240   40.081 1.000 119.920 ? 1262 ILE AAA H2   1 
ATOM   11   H H3   . ILE A 1 1   ? -8.163  3.331   40.645 1.000 119.920 ? 1262 ILE AAA H3   1 
ATOM   12   H HA   . ILE A 1 1   ? -7.965  5.301   39.859 1.000 119.110 ? 1262 ILE AAA HA   1 
ATOM   13   H HB   . ILE A 1 1   ? -8.478  4.342   37.260 1.000 109.440 ? 1262 ILE AAA HB   1 
ATOM   14   H HG12 . ILE A 1 1   ? -5.864  4.329   38.252 1.000 89.440  ? 1262 ILE AAA HG12 1 
ATOM   15   H HG13 . ILE A 1 1   ? -6.806  3.069   38.453 1.000 89.440  ? 1262 ILE AAA HG13 1 
ATOM   16   H HG21 . ILE A 1 1   ? -8.316  6.705   37.328 1.000 103.150 ? 1262 ILE AAA HG21 1 
ATOM   17   H HG22 . ILE A 1 1   ? -7.063  6.122   36.552 1.000 103.150 ? 1262 ILE AAA HG22 1 
ATOM   18   H HG23 . ILE A 1 1   ? -6.909  6.604   38.058 1.000 103.150 ? 1262 ILE AAA HG23 1 
ATOM   19   H HD11 . ILE A 1 1   ? -7.024  2.859   36.117 1.000 85.340  ? 1262 ILE AAA HD11 1 
ATOM   20   H HD12 . ILE A 1 1   ? -5.494  2.781   36.534 1.000 85.340  ? 1262 ILE AAA HD12 1 
ATOM   21   H HD13 . ILE A 1 1   ? -6.081  4.121   35.916 1.000 85.340  ? 1262 ILE AAA HD13 1 
ATOM   22   N N    . SER A 1 2   ? -10.621 5.560   38.109 1.000 114.290 ? 1263 SER AAA N    1 
ATOM   23   C CA   . SER A 1 2   ? -11.744 6.482   37.798 1.000 100.080 ? 1263 SER AAA CA   1 
ATOM   24   C C    . SER A 1 2   ? -13.046 5.704   37.586 1.000 102.920 ? 1263 SER AAA C    1 
ATOM   25   O O    . SER A 1 2   ? -13.149 5.053   36.538 1.000 101.960 ? 1263 SER AAA O    1 
ATOM   26   C CB   . SER A 1 2   ? -11.419 7.274   36.557 1.000 103.420 ? 1263 SER AAA CB   1 
ATOM   27   O OG   . SER A 1 2   ? -10.328 8.152   36.779 1.000 111.380 ? 1263 SER AAA OG   1 
ATOM   28   H H    . SER A 1 2   ? -10.271 4.949   37.385 1.000 114.290 ? 1263 SER AAA H    1 
ATOM   29   H HA   . SER A 1 2   ? -11.874 7.084   38.579 1.000 100.080 ? 1263 SER AAA HA   1 
ATOM   30   H HB2  . SER A 1 2   ? -11.193 6.655   35.826 1.000 103.420 ? 1263 SER AAA HB2  1 
ATOM   31   H HB3  . SER A 1 2   ? -12.208 7.799   36.290 1.000 103.420 ? 1263 SER AAA HB3  1 
ATOM   32   H HG   . SER A 1 2   ? -10.176 8.578   36.064 0.000 111.380 ? 1263 SER AAA HG   1 
ATOM   33   N N    . GLU A 1 3   ? -13.984 5.772   38.543 1.000 104.200 ? 1264 GLU AAA N    1 
ATOM   34   C CA   . GLU A 1 3   ? -15.440 5.443   38.400 1.000 83.520  ? 1264 GLU AAA CA   1 
ATOM   35   C C    . GLU A 1 3   ? -15.725 3.938   38.519 1.000 77.640  ? 1264 GLU AAA C    1 
ATOM   36   O O    . GLU A 1 3   ? -15.309 3.140   37.677 1.000 65.840  ? 1264 GLU AAA O    1 
ATOM   37   C CB   . GLU A 1 3   ? -15.972 5.995   37.084 1.000 81.110  ? 1264 GLU AAA CB   1 
ATOM   38   C CG   . GLU A 1 3   ? -17.386 6.508   37.220 1.000 91.330  ? 1264 GLU AAA CG   1 
ATOM   39   C CD   . GLU A 1 3   ? -18.068 6.847   35.907 1.000 87.170  ? 1264 GLU AAA CD   1 
ATOM   40   O OE1  . GLU A 1 3   ? -19.013 6.069   35.546 1.000 61.730  ? 1264 GLU AAA OE1  1 
ATOM   41   O OE2  . GLU A 1 3   ? -17.668 7.897   35.271 1.000 68.540  ? 1264 GLU AAA OE2  1 
ATOM   42   H H    . GLU A 1 3   ? -13.635 6.081   39.439 1.000 104.200 ? 1264 GLU AAA H    1 
ATOM   43   H HA   . GLU A 1 3   ? -15.934 5.890   39.126 1.000 83.520  ? 1264 GLU AAA HA   1 
ATOM   44   H HB2  . GLU A 1 3   ? -15.384 6.722   36.790 1.000 81.110  ? 1264 GLU AAA HB2  1 
ATOM   45   H HB3  . GLU A 1 3   ? -15.942 5.282   36.412 1.000 81.110  ? 1264 GLU AAA HB3  1 
ATOM   46   H HG2  . GLU A 1 3   ? -17.926 5.832   37.683 1.000 91.330  ? 1264 GLU AAA HG2  1 
ATOM   47   H HG3  . GLU A 1 3   ? -17.380 7.313   37.781 1.000 91.330  ? 1264 GLU AAA HG3  1 
ATOM   48   N N    . PRO A 1 4   ? -16.470 3.491   39.561 1.000 64.090  ? 1265 PRO AAA N    1 
ATOM   49   C CA   . PRO A 1 4   ? -16.659 2.063   39.812 1.000 61.780  ? 1265 PRO AAA CA   1 
ATOM   50   C C    . PRO A 1 4   ? -17.899 1.447   39.161 1.000 54.420  ? 1265 PRO AAA C    1 
ATOM   51   O O    . PRO A 1 4   ? -18.786 2.143   38.691 1.000 57.930  ? 1265 PRO AAA O    1 
ATOM   52   C CB   . PRO A 1 4   ? -16.751 2.066   41.343 1.000 59.690  ? 1265 PRO AAA CB   1 
ATOM   53   C CG   . PRO A 1 4   ? -17.518 3.336   41.665 1.000 63.150  ? 1265 PRO AAA CG   1 
ATOM   54   C CD   . PRO A 1 4   ? -17.139 4.322   40.578 1.000 62.510  ? 1265 PRO AAA CD   1 
ATOM   55   H HA   . PRO A 1 4   ? -15.865 1.566   39.490 1.000 61.780  ? 1265 PRO AAA HA   1 
ATOM   56   H HB2  . PRO A 1 4   ? -17.222 1.271   41.668 1.000 59.690  ? 1265 PRO AAA HB2  1 
ATOM   57   H HB3  . PRO A 1 4   ? -15.859 2.074   41.749 1.000 59.690  ? 1265 PRO AAA HB3  1 
ATOM   58   H HG2  . PRO A 1 4   ? -18.484 3.170   41.664 1.000 63.150  ? 1265 PRO AAA HG2  1 
ATOM   59   H HG3  . PRO A 1 4   ? -17.270 3.679   42.549 1.000 63.150  ? 1265 PRO AAA HG3  1 
ATOM   60   H HD2  . PRO A 1 4   ? -17.935 4.764   40.215 1.000 62.510  ? 1265 PRO AAA HD2  1 
ATOM   61   H HD3  . PRO A 1 4   ? -16.540 5.014   40.928 1.000 62.510  ? 1265 PRO AAA HD3  1 
ATOM   62   N N    . PRO A 1 5   ? -18.012 0.108   39.097 1.000 48.090  ? 1266 PRO AAA N    1 
ATOM   63   C CA   . PRO A 1 5   ? -19.102 -0.521  38.356 1.000 49.240  ? 1266 PRO AAA CA   1 
ATOM   64   C C    . PRO A 1 5   ? -20.481 -0.166  38.917 1.000 49.380  ? 1266 PRO AAA C    1 
ATOM   65   O O    . PRO A 1 5   ? -20.665 -0.197  40.109 1.000 49.070  ? 1266 PRO AAA O    1 
ATOM   66   C CB   . PRO A 1 5   ? -18.890 -2.030  38.551 1.000 54.120  ? 1266 PRO AAA CB   1 
ATOM   67   C CG   . PRO A 1 5   ? -17.441 -2.163  38.999 1.000 52.340  ? 1266 PRO AAA CG   1 
ATOM   68   C CD   . PRO A 1 5   ? -17.080 -0.861  39.684 1.000 46.800  ? 1266 PRO AAA CD   1 
ATOM   69   H HA   . PRO A 1 5   ? -19.054 -0.245  37.406 1.000 49.240  ? 1266 PRO AAA HA   1 
ATOM   70   H HB2  . PRO A 1 5   ? -19.503 -2.387  39.228 1.000 54.120  ? 1266 PRO AAA HB2  1 
ATOM   71   H HB3  . PRO A 1 5   ? -19.047 -2.518  37.716 1.000 54.120  ? 1266 PRO AAA HB3  1 
ATOM   72   H HG2  . PRO A 1 5   ? -17.335 -2.914  39.620 1.000 52.340  ? 1266 PRO AAA HG2  1 
ATOM   73   H HG3  . PRO A 1 5   ? -16.851 -2.318  38.232 1.000 52.340  ? 1266 PRO AAA HG3  1 
ATOM   74   H HD2  . PRO A 1 5   ? -17.195 -0.933  40.654 1.000 46.800  ? 1266 PRO AAA HD2  1 
ATOM   75   H HD3  . PRO A 1 5   ? -16.147 -0.620  39.507 1.000 46.800  ? 1266 PRO AAA HD3  1 
ATOM   76   N N    . LEU A 1 6   ? -21.436 0.066   38.033 1.000 45.070  ? 1267 LEU AAA N    1 
ATOM   77   C CA   . LEU A 1 6   ? -22.840 0.365   38.400 1.000 39.380  ? 1267 LEU AAA CA   1 
ATOM   78   C C    . LEU A 1 6   ? -23.638 -0.919  38.619 1.000 39.700  ? 1267 LEU AAA C    1 
ATOM   79   O O    . LEU A 1 6   ? -24.680 -0.840  39.238 1.000 44.680  ? 1267 LEU AAA O    1 
ATOM   80   C CB   . LEU A 1 6   ? -23.457 1.153   37.249 1.000 43.670  ? 1267 LEU AAA CB   1 
ATOM   81   C CG   . LEU A 1 6   ? -22.857 2.535   37.032 1.000 46.480  ? 1267 LEU AAA CG   1 
ATOM   82   C CD1  . LEU A 1 6   ? -23.679 3.290   36.002 1.000 46.530  ? 1267 LEU AAA CD1  1 
ATOM   83   C CD2  . LEU A 1 6   ? -22.811 3.306   38.350 1.000 47.170  ? 1267 LEU AAA CD2  1 
ATOM   84   H H    . LEU A 1 6   ? -21.178 0.034   37.057 1.000 45.070  ? 1267 LEU AAA H    1 
ATOM   85   H HA   . LEU A 1 6   ? -22.841 0.870   39.246 1.000 39.380  ? 1267 LEU AAA HA   1 
ATOM   86   H HB2  . LEU A 1 6   ? -23.354 0.631   36.429 1.000 43.670  ? 1267 LEU AAA HB2  1 
ATOM   87   H HB3  . LEU A 1 6   ? -24.415 1.247   37.420 1.000 43.670  ? 1267 LEU AAA HB3  1 
ATOM   88   H HG   . LEU A 1 6   ? -21.930 2.419   36.707 1.000 46.480  ? 1267 LEU AAA HG   1 
ATOM   89   H HD11 . LEU A 1 6   ? -23.676 2.800   35.162 1.000 46.530  ? 1267 LEU AAA HD11 1 
ATOM   90   H HD12 . LEU A 1 6   ? -23.295 4.173   35.865 1.000 46.530  ? 1267 LEU AAA HD12 1 
ATOM   91   H HD13 . LEU A 1 6   ? -24.594 3.381   36.320 1.000 46.530  ? 1267 LEU AAA HD13 1 
ATOM   92   H HD21 . LEU A 1 6   ? -23.713 3.402   38.701 1.000 47.170  ? 1267 LEU AAA HD21 1 
ATOM   93   H HD22 . LEU A 1 6   ? -22.425 4.186   38.198 1.000 47.170  ? 1267 LEU AAA HD22 1 
ATOM   94   H HD23 . LEU A 1 6   ? -22.264 2.820   38.992 1.000 47.170  ? 1267 LEU AAA HD23 1 
ATOM   95   N N    . HIS A 1 7   ? -23.216 -2.041  38.048 1.000 39.870  ? 1268 HIS AAA N    1 
ATOM   96   C CA   . HIS A 1 7   ? -23.960 -3.316  38.097 1.000 38.910  ? 1268 HIS AAA CA   1 
ATOM   97   C C    . HIS A 1 7   ? -22.976 -4.448  38.379 1.000 41.250  ? 1268 HIS AAA C    1 
ATOM   98   O O    . HIS A 1 7   ? -21.749 -4.269  38.160 1.000 42.370  ? 1268 HIS AAA O    1 
ATOM   99   C CB   . HIS A 1 7   ? -24.735 -3.571  36.790 1.000 38.440  ? 1268 HIS AAA CB   1 
ATOM   100  C CG   . HIS A 1 7   ? -25.597 -2.433  36.400 1.000 42.920  ? 1268 HIS AAA CG   1 
ATOM   101  N ND1  . HIS A 1 7   ? -26.814 -2.207  37.007 1.000 44.690  ? 1268 HIS AAA ND1  1 
ATOM   102  C CD2  . HIS A 1 7   ? -25.400 -1.422  35.519 1.000 46.000  ? 1268 HIS AAA CD2  1 
ATOM   103  C CE1  . HIS A 1 7   ? -27.350 -1.104  36.514 1.000 44.920  ? 1268 HIS AAA CE1  1 
ATOM   104  N NE2  . HIS A 1 7   ? -26.502 -0.599  35.592 1.000 45.290  ? 1268 HIS AAA NE2  1 
ATOM   105  H H    . HIS A 1 7   ? -22.335 -2.004  37.556 1.000 39.870  ? 1268 HIS AAA H    1 
ATOM   106  H HA   . HIS A 1 7   ? -24.605 -3.265  38.841 1.000 38.910  ? 1268 HIS AAA HA   1 
ATOM   107  H HB2  . HIS A 1 7   ? -24.090 -3.749  36.070 1.000 38.440  ? 1268 HIS AAA HB2  1 
ATOM   108  H HB3  . HIS A 1 7   ? -25.291 -4.373  36.904 1.000 38.440  ? 1268 HIS AAA HB3  1 
ATOM   109  H HD1  . HIS A 1 7   ? -27.161 -2.697  37.645 0.000 44.690  ? 1268 HIS AAA HD1  1 
ATOM   110  H HD2  . HIS A 1 7   ? -24.655 -1.300  34.961 1.000 46.000  ? 1268 HIS AAA HD2  1 
ATOM   111  H HE1  . HIS A 1 7   ? -28.180 -0.736  36.766 1.000 44.920  ? 1268 HIS AAA HE1  1 
ATOM   112  H HE2  . HIS A 1 7   ? -26.635 0.131   35.124 0.000 45.290  ? 1268 HIS AAA HE2  1 
ATOM   113  N N    . ASP A 1 8   ? -23.526 -5.593  38.758 1.000 36.850  ? 1269 ASP AAA N    1 
ATOM   114  C CA   . ASP A 1 8   ? -22.749 -6.834  38.943 1.000 41.540  ? 1269 ASP AAA CA   1 
ATOM   115  C C    . ASP A 1 8   ? -22.126 -7.238  37.594 1.000 42.940  ? 1269 ASP AAA C    1 
ATOM   116  O O    . ASP A 1 8   ? -20.940 -7.621  37.591 1.000 40.550  ? 1269 ASP AAA O    1 
ATOM   117  C CB   . ASP A 1 8   ? -23.614 -7.918  39.606 1.000 42.490  ? 1269 ASP AAA CB   1 
ATOM   118  C CG   . ASP A 1 8   ? -23.750 -7.808  41.117 1.000 40.270  ? 1269 ASP AAA CG   1 
ATOM   119  O OD1  . ASP A 1 8   ? -22.951 -7.055  41.766 1.000 37.150  ? 1269 ASP AAA OD1  1 
ATOM   120  O OD2  . ASP A 1 8   ? -24.658 -8.485  41.647 1.000 42.460  ? 1269 ASP AAA OD2  1 
ATOM   121  H H    . ASP A 1 8   ? -24.522 -5.606  38.925 1.000 36.850  ? 1269 ASP AAA H    1 
ATOM   122  H HA   . ASP A 1 8   ? -22.026 -6.657  39.590 1.000 41.540  ? 1269 ASP AAA HA   1 
ATOM   123  H HB2  . ASP A 1 8   ? -24.518 -7.864  39.235 1.000 42.490  ? 1269 ASP AAA HB2  1 
ATOM   124  H HB3  . ASP A 1 8   ? -23.214 -8.792  39.420 1.000 42.490  ? 1269 ASP AAA HB3  1 
ATOM   125  N N    . PHE A 1 9   ? -22.869 -7.165  36.486 1.000 40.220  ? 1270 PHE AAA N    1 
ATOM   126  C CA   . PHE A 1 9   ? -22.310 -7.511  35.162 1.000 37.970  ? 1270 PHE AAA CA   1 
ATOM   127  C C    . PHE A 1 9   ? -21.403 -6.352  34.758 1.000 39.370  ? 1270 PHE AAA C    1 
ATOM   128  O O    . PHE A 1 9   ? -21.805 -5.183  34.847 1.000 39.840  ? 1270 PHE AAA O    1 
ATOM   129  C CB   . PHE A 1 9   ? -23.376 -7.798  34.110 1.000 38.340  ? 1270 PHE AAA CB   1 
ATOM   130  C CG   . PHE A 1 9   ? -22.770 -8.375  32.867 1.000 41.300  ? 1270 PHE AAA CG   1 
ATOM   131  C CD1  . PHE A 1 9   ? -22.124 -7.560  31.948 1.000 43.550  ? 1270 PHE AAA CD1  1 
ATOM   132  C CD2  . PHE A 1 9   ? -22.762 -9.743  32.650 1.000 44.590  ? 1270 PHE AAA CD2  1 
ATOM   133  C CE1  . PHE A 1 9   ? -21.508 -8.091  30.827 1.000 40.350  ? 1270 PHE AAA CE1  1 
ATOM   134  C CE2  . PHE A 1 9   ? -22.132 -10.272 31.528 1.000 40.310  ? 1270 PHE AAA CE2  1 
ATOM   135  C CZ   . PHE A 1 9   ? -21.499 -9.450  30.629 1.000 38.880  ? 1270 PHE AAA CZ   1 
ATOM   136  H H    . PHE A 1 9   ? -23.832 -6.868  36.552 1.000 40.220  ? 1270 PHE AAA H    1 
ATOM   137  H HA   . PHE A 1 9   ? -21.775 -8.341  35.252 1.000 37.970  ? 1270 PHE AAA HA   1 
ATOM   138  H HB2  . PHE A 1 9   ? -24.032 -8.416  34.494 1.000 38.340  ? 1270 PHE AAA HB2  1 
ATOM   139  H HB3  . PHE A 1 9   ? -23.847 -6.962  33.910 1.000 38.340  ? 1270 PHE AAA HB3  1 
ATOM   140  H HD1  . PHE A 1 9   ? -22.066 -6.632  32.108 1.000 43.550  ? 1270 PHE AAA HD1  1 
ATOM   141  H HD2  . PHE A 1 9   ? -23.186 -10.320 33.266 1.000 44.590  ? 1270 PHE AAA HD2  1 
ATOM   142  H HE1  . PHE A 1 9   ? -21.074 -7.518  30.215 1.000 40.350  ? 1270 PHE AAA HE1  1 
ATOM   143  H HE2  . PHE A 1 9   ? -22.128 -11.207 31.395 1.000 40.310  ? 1270 PHE AAA HE2  1 
ATOM   144  H HZ   . PHE A 1 9   ? -21.079 -9.813  29.865 1.000 38.880  ? 1270 PHE AAA HZ   1 
ATOM   145  N N    . TYR A 1 10  ? -20.183 -6.664  34.344 1.000 38.580  ? 1271 TYR AAA N    1 
ATOM   146  C CA   . TYR A 1 10  ? -19.168 -5.647  33.988 1.000 41.090  ? 1271 TYR AAA CA   1 
ATOM   147  C C    . TYR A 1 10  ? -18.111 -6.259  33.080 1.000 40.990  ? 1271 TYR AAA C    1 
ATOM   148  O O    . TYR A 1 10  ? -17.285 -7.012  33.573 1.000 41.580  ? 1271 TYR AAA O    1 
ATOM   149  C CB   . TYR A 1 10  ? -18.572 -5.135  35.275 1.000 41.180  ? 1271 TYR AAA CB   1 
ATOM   150  C CG   . TYR A 1 10  ? -17.592 -4.007  35.205 1.000 41.120  ? 1271 TYR AAA CG   1 
ATOM   151  C CD1  . TYR A 1 10  ? -18.018 -2.717  34.958 1.000 39.880  ? 1271 TYR AAA CD1  1 
ATOM   152  C CD2  . TYR A 1 10  ? -16.279 -4.210  35.616 1.000 44.630  ? 1271 TYR AAA CD2  1 
ATOM   153  C CE1  . TYR A 1 10  ? -17.138 -1.650  35.043 1.000 43.070  ? 1271 TYR AAA CE1  1 
ATOM   154  C CE2  . TYR A 1 10  ? -15.375 -3.162  35.684 1.000 47.100  ? 1271 TYR AAA CE2  1 
ATOM   155  C CZ   . TYR A 1 10  ? -15.815 -1.876  35.400 1.000 50.520  ? 1271 TYR AAA CZ   1 
ATOM   156  O OH   . TYR A 1 10  ? -14.929 -0.844  35.461 1.000 49.230  ? 1271 TYR AAA OH   1 
ATOM   157  H H    . TYR A 1 10  ? -19.946 -7.643  34.272 1.000 38.580  ? 1271 TYR AAA H    1 
ATOM   158  H HA   . TYR A 1 10  ? -19.615 -4.915  33.492 1.000 41.090  ? 1271 TYR AAA HA   1 
ATOM   159  H HB2  . TYR A 1 10  ? -19.302 -4.843  35.860 1.000 41.180  ? 1271 TYR AAA HB2  1 
ATOM   160  H HB3  . TYR A 1 10  ? -18.119 -5.879  35.724 1.000 41.180  ? 1271 TYR AAA HB3  1 
ATOM   161  H HD1  . TYR A 1 10  ? -18.917 -2.565  34.730 1.000 39.880  ? 1271 TYR AAA HD1  1 
ATOM   162  H HD2  . TYR A 1 10  ? -15.996 -5.078  35.854 1.000 44.630  ? 1271 TYR AAA HD2  1 
ATOM   163  H HE1  . TYR A 1 10  ? -17.439 -0.773  34.872 1.000 43.070  ? 1271 TYR AAA HE1  1 
ATOM   164  H HE2  . TYR A 1 10  ? -14.476 -3.310  35.926 1.000 47.100  ? 1271 TYR AAA HE2  1 
ATOM   165  H HH   . TYR A 1 10  ? -15.193 -0.264  36.036 0.000 49.230  ? 1271 TYR AAA HH   1 
ATOM   166  N N    . CYS A 1 11  ? -18.189 -5.938  31.790 1.000 41.790  ? 1272 CYS AAA N    1 
ATOM   167  C CA   . CYS A 1 11  ? -17.306 -6.467  30.726 1.000 47.050  ? 1272 CYS AAA CA   1 
ATOM   168  C C    . CYS A 1 11  ? -15.991 -5.691  30.781 1.000 44.060  ? 1272 CYS AAA C    1 
ATOM   169  O O    . CYS A 1 11  ? -15.992 -4.475  30.445 1.000 42.480  ? 1272 CYS AAA O    1 
ATOM   170  C CB   . CYS A 1 11  ? -17.946 -6.377  29.342 1.000 48.910  ? 1272 CYS AAA CB   1 
ATOM   171  S SG   . CYS A 1 11  ? -16.996 -7.251  28.072 1.000 49.030  ? 1272 CYS AAA SG   1 
ATOM   172  H H    . CYS A 1 11  ? -18.916 -5.281  31.545 1.000 41.790  ? 1272 CYS AAA H    1 
ATOM   173  H HA   . CYS A 1 11  ? -17.133 -7.417  30.919 1.000 47.050  ? 1272 CYS AAA HA   1 
ATOM   174  H HB2  . CYS A 1 11  ? -18.848 -6.756  29.380 1.000 48.910  ? 1272 CYS AAA HB2  1 
ATOM   175  H HB3  . CYS A 1 11  ? -18.026 -5.435  29.086 1.000 48.910  ? 1272 CYS AAA HB3  1 
ATOM   176  N N    . SER A 1 12  ? -14.941 -6.372  31.258 1.000 45.730  ? 1273 SER AAA N    1 
ATOM   177  C CA   . SER A 1 12  ? -13.552 -5.866  31.333 1.000 45.690  ? 1273 SER AAA CA   1 
ATOM   178  C C    . SER A 1 12  ? -12.725 -6.602  30.276 1.000 48.280  ? 1273 SER AAA C    1 
ATOM   179  O O    . SER A 1 12  ? -11.997 -7.554  30.607 1.000 50.920  ? 1273 SER AAA O    1 
ATOM   180  C CB   . SER A 1 12  ? -13.006 -6.007  32.715 1.000 47.850  ? 1273 SER AAA CB   1 
ATOM   181  O OG   . SER A 1 12  ? -11.645 -5.608  32.767 1.000 47.120  ? 1273 SER AAA OG   1 
ATOM   182  H H    . SER A 1 12  ? -15.144 -7.305  31.587 1.000 45.730  ? 1273 SER AAA H    1 
ATOM   183  H HA   . SER A 1 12  ? -13.566 -4.895  31.118 1.000 45.690  ? 1273 SER AAA HA   1 
ATOM   184  H HB2  . SER A 1 12  ? -13.533 -5.449  33.331 1.000 47.850  ? 1273 SER AAA HB2  1 
ATOM   185  H HB3  . SER A 1 12  ? -13.081 -6.946  33.000 1.000 47.850  ? 1273 SER AAA HB3  1 
ATOM   186  H HG   . SER A 1 12  ? -11.368 -5.700  33.561 0.000 47.120  ? 1273 SER AAA HG   1 
ATOM   187  N N    . ARG A 1 13  ? -12.884 -6.196  29.016 1.000 45.330  ? 1274 ARG AAA N    1 
ATOM   188  C CA   . ARG A 1 13  ? -12.186 -6.838  27.884 1.000 45.470  ? 1274 ARG AAA CA   1 
ATOM   189  C C    . ARG A 1 13  ? -11.763 -5.772  26.877 1.000 45.880  ? 1274 ARG AAA C    1 
ATOM   190  O O    . ARG A 1 13  ? -12.066 -4.566  27.103 1.000 39.350  ? 1274 ARG AAA O    1 
ATOM   191  C CB   . ARG A 1 13  ? -13.095 -7.902  27.299 1.000 46.220  ? 1274 ARG AAA CB   1 
ATOM   192  C CG   . ARG A 1 13  ? -13.481 -8.976  28.299 1.000 48.750  ? 1274 ARG AAA CG   1 
ATOM   193  C CD   . ARG A 1 13  ? -13.775 -10.235 27.538 1.000 49.210  ? 1274 ARG AAA CD   1 
ATOM   194  N NE   . ARG A 1 13  ? -14.514 -11.157 28.350 1.000 56.220  ? 1274 ARG AAA NE   1 
ATOM   195  C CZ   . ARG A 1 13  ? -14.647 -12.444 28.069 1.000 64.200  ? 1274 ARG AAA CZ   1 
ATOM   196  N NH1  . ARG A 1 13  ? -14.068 -12.950 26.995 1.000 62.610  ? 1274 ARG AAA NH1  1 
ATOM   197  N NH2  . ARG A 1 13  ? -15.378 -13.218 28.852 1.000 67.630  ? 1274 ARG AAA NH2  1 
ATOM   198  H H    . ARG A 1 13  ? -13.506 -5.421  28.835 1.000 45.330  ? 1274 ARG AAA H    1 
ATOM   199  H HA   . ARG A 1 13  ? -11.379 -7.286  28.228 1.000 45.470  ? 1274 ARG AAA HA   1 
ATOM   200  H HB2  . ARG A 1 13  ? -13.907 -7.468  26.962 1.000 46.220  ? 1274 ARG AAA HB2  1 
ATOM   201  H HB3  . ARG A 1 13  ? -12.638 -8.318  26.538 1.000 46.220  ? 1274 ARG AAA HB3  1 
ATOM   202  H HG2  . ARG A 1 13  ? -12.744 -9.109  28.932 1.000 48.750  ? 1274 ARG AAA HG2  1 
ATOM   203  H HG3  . ARG A 1 13  ? -14.265 -8.678  28.807 1.000 48.750  ? 1274 ARG AAA HG3  1 
ATOM   204  H HD2  . ARG A 1 13  ? -14.287 -10.012 26.731 1.000 49.210  ? 1274 ARG AAA HD2  1 
ATOM   205  H HD3  . ARG A 1 13  ? -12.930 -10.643 27.250 1.000 49.210  ? 1274 ARG AAA HD3  1 
ATOM   206  H HE   . ARG A 1 13  ? -14.897 -10.850 29.070 1.000 56.220  ? 1274 ARG AAA HE   1 
ATOM   207  H HH11 . ARG A 1 13  ? -13.594 -12.430 26.467 1.000 62.610  ? 1274 ARG AAA HH11 1 
ATOM   208  H HH12 . ARG A 1 13  ? -14.158 -13.805 26.811 1.000 62.610  ? 1274 ARG AAA HH12 1 
ATOM   209  H HH21 . ARG A 1 13  ? -15.775 -12.876 29.560 1.000 67.630  ? 1274 ARG AAA HH21 1 
ATOM   210  H HH22 . ARG A 1 13  ? -15.466 -14.074 28.664 1.000 67.630  ? 1274 ARG AAA HH22 1 
ATOM   211  N N    . LEU A 1 14  ? -11.014 -6.209  25.866 1.000 45.820  ? 1275 LEU AAA N    1 
ATOM   212  C CA   . LEU A 1 14  ? -10.428 -5.342  24.812 1.000 51.600  ? 1275 LEU AAA CA   1 
ATOM   213  C C    . LEU A 1 14  ? -11.421 -5.326  23.654 1.000 48.190  ? 1275 LEU AAA C    1 
ATOM   214  O O    . LEU A 1 14  ? -11.505 -6.347  22.936 1.000 44.750  ? 1275 LEU AAA O    1 
ATOM   215  C CB   . LEU A 1 14  ? -9.060  -5.911  24.409 1.000 56.610  ? 1275 LEU AAA CB   1 
ATOM   216  C CG   . LEU A 1 14  ? -7.857  -5.409  25.219 1.000 57.960  ? 1275 LEU AAA CG   1 
ATOM   217  C CD1  . LEU A 1 14  ? -8.181  -5.085  26.668 1.000 54.040  ? 1275 LEU AAA CD1  1 
ATOM   218  C CD2  . LEU A 1 14  ? -6.754  -6.421  25.182 1.000 56.920  ? 1275 LEU AAA CD2  1 
ATOM   219  H H    . LEU A 1 14  ? -10.846 -7.204  25.834 1.000 45.820  ? 1275 LEU AAA H    1 
ATOM   220  H HA   . LEU A 1 14  ? -10.322 -4.434  25.178 1.000 51.600  ? 1275 LEU AAA HA   1 
ATOM   221  H HB2  . LEU A 1 14  ? -9.096  -6.885  24.489 1.000 56.610  ? 1275 LEU AAA HB2  1 
ATOM   222  H HB3  . LEU A 1 14  ? -8.904  -5.698  23.467 1.000 56.610  ? 1275 LEU AAA HB3  1 
ATOM   223  H HG   . LEU A 1 14  ? -7.531  -4.575  24.799 1.000 57.960  ? 1275 LEU AAA HG   1 
ATOM   224  H HD11 . LEU A 1 14  ? -8.861  -4.390  26.701 1.000 54.040  ? 1275 LEU AAA HD11 1 
ATOM   225  H HD12 . LEU A 1 14  ? -7.376  -4.775  27.119 1.000 54.040  ? 1275 LEU AAA HD12 1 
ATOM   226  H HD13 . LEU A 1 14  ? -8.514  -5.884  27.113 1.000 54.040  ? 1275 LEU AAA HD13 1 
ATOM   227  H HD21 . LEU A 1 14  ? -7.069  -7.259  25.563 1.000 56.920  ? 1275 LEU AAA HD21 1 
ATOM   228  H HD22 . LEU A 1 14  ? -5.996  -6.094  25.697 1.000 56.920  ? 1275 LEU AAA HD22 1 
ATOM   229  H HD23 . LEU A 1 14  ? -6.479  -6.568  24.260 1.000 56.920  ? 1275 LEU AAA HD23 1 
ATOM   230  N N    . LEU A 1 15  ? -12.223 -4.266  23.577 1.000 41.220  ? 1276 LEU AAA N    1 
ATOM   231  C CA   . LEU A 1 15  ? -13.352 -4.218  22.624 1.000 42.020  ? 1276 LEU AAA CA   1 
ATOM   232  C C    . LEU A 1 15  ? -13.581 -2.790  22.121 1.000 43.030  ? 1276 LEU AAA C    1 
ATOM   233  O O    . LEU A 1 15  ? -13.713 -1.872  22.961 1.000 41.270  ? 1276 LEU AAA O    1 
ATOM   234  C CB   . LEU A 1 15  ? -14.579 -4.772  23.335 1.000 46.970  ? 1276 LEU AAA CB   1 
ATOM   235  C CG   . LEU A 1 15  ? -15.874 -4.817  22.526 1.000 52.320  ? 1276 LEU AAA CG   1 
ATOM   236  C CD1  . LEU A 1 15  ? -15.756 -5.665  21.255 1.000 51.550  ? 1276 LEU AAA CD1  1 
ATOM   237  C CD2  . LEU A 1 15  ? -16.999 -5.323  23.417 1.000 58.950  ? 1276 LEU AAA CD2  1 
ATOM   238  H H    . LEU A 1 15  ? -12.057 -3.476  24.184 1.000 41.220  ? 1276 LEU AAA H    1 
ATOM   239  H HA   . LEU A 1 15  ? -13.130 -4.783  21.848 1.000 42.020  ? 1276 LEU AAA HA   1 
ATOM   240  H HB2  . LEU A 1 15  ? -14.378 -5.682  23.631 1.000 46.970  ? 1276 LEU AAA HB2  1 
ATOM   241  H HB3  . LEU A 1 15  ? -14.741 -4.232  24.134 1.000 46.970  ? 1276 LEU AAA HB3  1 
ATOM   242  H HG   . LEU A 1 15  ? -16.086 -3.896  22.235 1.000 52.320  ? 1276 LEU AAA HG   1 
ATOM   243  H HD11 . LEU A 1 15  ? -15.061 -5.296  20.682 1.000 51.550  ? 1276 LEU AAA HD11 1 
ATOM   244  H HD12 . LEU A 1 15  ? -16.606 -5.660  20.781 1.000 51.550  ? 1276 LEU AAA HD12 1 
ATOM   245  H HD13 . LEU A 1 15  ? -15.526 -6.579  21.495 1.000 51.550  ? 1276 LEU AAA HD13 1 
ATOM   246  H HD21 . LEU A 1 15  ? -16.782 -6.215  23.739 1.000 58.950  ? 1276 LEU AAA HD21 1 
ATOM   247  H HD22 . LEU A 1 15  ? -17.828 -5.353  22.908 1.000 58.950  ? 1276 LEU AAA HD22 1 
ATOM   248  H HD23 . LEU A 1 15  ? -17.107 -4.723  24.175 1.000 58.950  ? 1276 LEU AAA HD23 1 
ATOM   249  N N    . ASP A 1 16  ? -13.568 -2.623  20.790 1.000 41.510  ? 1277 ASP AAA N    1 
ATOM   250  C CA   . ASP A 1 16  ? -14.056 -1.406  20.094 1.000 43.280  ? 1277 ASP AAA CA   1 
ATOM   251  C C    . ASP A 1 16  ? -15.502 -1.667  19.668 1.000 37.140  ? 1277 ASP AAA C    1 
ATOM   252  O O    . ASP A 1 16  ? -15.695 -2.469  18.772 1.000 41.680  ? 1277 ASP AAA O    1 
ATOM   253  C CB   . ASP A 1 16  ? -13.110 -1.084  18.934 1.000 48.980  ? 1277 ASP AAA CB   1 
ATOM   254  C CG   . ASP A 1 16  ? -11.794 -0.419  19.340 1.000 51.210  ? 1277 ASP AAA CG   1 
ATOM   255  O OD1  . ASP A 1 16  ? -11.647 -0.030  20.518 1.000 53.350  ? 1277 ASP AAA OD1  1 
ATOM   256  O OD2  . ASP A 1 16  ? -10.930 -0.271  18.470 1.000 54.090  ? 1277 ASP AAA OD2  1 
ATOM   257  H H    . ASP A 1 16  ? -13.198 -3.388  20.244 1.000 41.510  ? 1277 ASP AAA H    1 
ATOM   258  H HA   . ASP A 1 16  ? -14.029 -0.651  20.728 1.000 43.280  ? 1277 ASP AAA HA   1 
ATOM   259  H HB2  . ASP A 1 16  ? -12.881 -1.920  18.479 1.000 48.980  ? 1277 ASP AAA HB2  1 
ATOM   260  H HB3  . ASP A 1 16  ? -13.566 -0.469  18.323 1.000 48.980  ? 1277 ASP AAA HB3  1 
ATOM   261  N N    . LEU A 1 17  ? -16.482 -1.098  20.356 1.000 38.830  ? 1278 LEU AAA N    1 
ATOM   262  C CA   . LEU A 1 17  ? -17.926 -1.388  20.126 1.000 39.150  ? 1278 LEU AAA CA   1 
ATOM   263  C C    . LEU A 1 17  ? -18.626 -0.123  19.588 1.000 38.620  ? 1278 LEU AAA C    1 
ATOM   264  O O    . LEU A 1 17  ? -18.624 0.922   20.305 1.000 38.640  ? 1278 LEU AAA O    1 
ATOM   265  C CB   . LEU A 1 17  ? -18.582 -1.903  21.420 1.000 39.100  ? 1278 LEU AAA CB   1 
ATOM   266  C CG   . LEU A 1 17  ? -20.109 -2.087  21.370 1.000 41.620  ? 1278 LEU AAA CG   1 
ATOM   267  C CD1  . LEU A 1 17  ? -20.535 -3.196  20.403 1.000 38.490  ? 1278 LEU AAA CD1  1 
ATOM   268  C CD2  . LEU A 1 17  ? -20.694 -2.338  22.758 1.000 41.380  ? 1278 LEU AAA CD2  1 
ATOM   269  H H    . LEU A 1 17  ? -16.221 -0.434  21.071 1.000 38.830  ? 1278 LEU AAA H    1 
ATOM   270  H HA   . LEU A 1 17  ? -17.998 -2.100  19.450 1.000 39.150  ? 1278 LEU AAA HA   1 
ATOM   271  H HB2  . LEU A 1 17  ? -18.177 -2.763  21.649 1.000 39.100  ? 1278 LEU AAA HB2  1 
ATOM   272  H HB3  . LEU A 1 17  ? -18.372 -1.277  22.142 1.000 39.100  ? 1278 LEU AAA HB3  1 
ATOM   273  H HG   . LEU A 1 17  ? -20.507 -1.251  21.024 1.000 41.620  ? 1278 LEU AAA HG   1 
ATOM   274  H HD11 . LEU A 1 17  ? -20.229 -2.979  19.505 1.000 38.490  ? 1278 LEU AAA HD11 1 
ATOM   275  H HD12 . LEU A 1 17  ? -21.505 -3.275  20.407 1.000 38.490  ? 1278 LEU AAA HD12 1 
ATOM   276  H HD13 . LEU A 1 17  ? -20.141 -4.040  20.683 1.000 38.490  ? 1278 LEU AAA HD13 1 
ATOM   277  H HD21 . LEU A 1 17  ? -20.300 -3.144  23.135 1.000 41.380  ? 1278 LEU AAA HD21 1 
ATOM   278  H HD22 . LEU A 1 17  ? -21.658 -2.448  22.689 1.000 41.380  ? 1278 LEU AAA HD22 1 
ATOM   279  H HD23 . LEU A 1 17  ? -20.496 -1.580  23.336 1.000 41.380  ? 1278 LEU AAA HD23 1 
ATOM   280  N N    . VAL A 1 18  ? -19.296 -0.267  18.435 1.000 37.990  ? 1279 VAL AAA N    1 
ATOM   281  C CA   . VAL A 1 18  ? -20.012 0.826   17.707 1.000 42.670  ? 1279 VAL AAA CA   1 
ATOM   282  C C    . VAL A 1 18  ? -21.535 0.579   17.697 1.000 39.650  ? 1279 VAL AAA C    1 
ATOM   283  O O    . VAL A 1 18  ? -22.011 -0.410  17.064 1.000 36.700  ? 1279 VAL AAA O    1 
ATOM   284  C CB   . VAL A 1 18  ? -19.474 0.952   16.268 1.000 43.680  ? 1279 VAL AAA CB   1 
ATOM   285  C CG1  . VAL A 1 18  ? -20.155 2.090   15.519 1.000 45.230  ? 1279 VAL AAA CG1  1 
ATOM   286  C CG2  . VAL A 1 18  ? -17.961 1.095   16.241 1.000 41.080  ? 1279 VAL AAA CG2  1 
ATOM   287  H H    . VAL A 1 18  ? -19.301 -1.201  18.050 1.000 37.990  ? 1279 VAL AAA H    1 
ATOM   288  H HA   . VAL A 1 18  ? -19.855 1.664   18.178 1.000 42.670  ? 1279 VAL AAA HA   1 
ATOM   289  H HB   . VAL A 1 18  ? -19.703 0.114   15.795 1.000 43.680  ? 1279 VAL AAA HB   1 
ATOM   290  H HG11 . VAL A 1 18  ? -21.113 1.924   15.478 1.000 45.230  ? 1279 VAL AAA HG11 1 
ATOM   291  H HG12 . VAL A 1 18  ? -19.796 2.146   14.616 1.000 45.230  ? 1279 VAL AAA HG12 1 
ATOM   292  H HG13 . VAL A 1 18  ? -19.992 2.929   15.984 1.000 45.230  ? 1279 VAL AAA HG13 1 
ATOM   293  H HG21 . VAL A 1 18  ? -17.701 1.892   16.735 1.000 41.080  ? 1279 VAL AAA HG21 1 
ATOM   294  H HG22 . VAL A 1 18  ? -17.658 1.171   15.319 1.000 41.080  ? 1279 VAL AAA HG22 1 
ATOM   295  H HG23 . VAL A 1 18  ? -17.553 0.313   16.652 1.000 41.080  ? 1279 VAL AAA HG23 1 
ATOM   296  N N    . PHE A 1 19  ? -22.274 1.492   18.311 1.000 33.020  ? 1280 PHE AAA N    1 
ATOM   297  C CA   . PHE A 1 19  ? -23.745 1.479   18.360 1.000 37.590  ? 1280 PHE AAA CA   1 
ATOM   298  C C    . PHE A 1 19  ? -24.295 2.282   17.182 1.000 42.730  ? 1280 PHE AAA C    1 
ATOM   299  O O    . PHE A 1 19  ? -23.980 3.490   17.127 1.000 37.690  ? 1280 PHE AAA O    1 
ATOM   300  C CB   . PHE A 1 19  ? -24.203 2.084   19.686 1.000 43.260  ? 1280 PHE AAA CB   1 
ATOM   301  C CG   . PHE A 1 19  ? -23.865 1.296   20.931 1.000 43.910  ? 1280 PHE AAA CG   1 
ATOM   302  C CD1  . PHE A 1 19  ? -24.681 0.259   21.365 1.000 41.580  ? 1280 PHE AAA CD1  1 
ATOM   303  C CD2  . PHE A 1 19  ? -22.763 1.633   21.704 1.000 48.030  ? 1280 PHE AAA CD2  1 
ATOM   304  C CE1  . PHE A 1 19  ? -24.394 -0.423  22.538 1.000 43.910  ? 1280 PHE AAA CE1  1 
ATOM   305  C CE2  . PHE A 1 19  ? -22.479 0.947   22.876 1.000 45.750  ? 1280 PHE AAA CE2  1 
ATOM   306  C CZ   . PHE A 1 19  ? -23.288 -0.088  23.284 1.000 40.350  ? 1280 PHE AAA CZ   1 
ATOM   307  H H    . PHE A 1 19  ? -21.773 2.239   18.770 1.000 33.020  ? 1280 PHE AAA H    1 
ATOM   308  H HA   . PHE A 1 19  ? -24.056 0.542   18.275 1.000 37.590  ? 1280 PHE AAA HA   1 
ATOM   309  H HB2  . PHE A 1 19  ? -23.806 2.976   19.773 1.000 43.260  ? 1280 PHE AAA HB2  1 
ATOM   310  H HB3  . PHE A 1 19  ? -25.176 2.200   19.654 1.000 43.260  ? 1280 PHE AAA HB3  1 
ATOM   311  H HD1  . PHE A 1 19  ? -25.459 0.042   20.876 1.000 41.580  ? 1280 PHE AAA HD1  1 
ATOM   312  H HD2  . PHE A 1 19  ? -22.201 2.339   21.426 1.000 48.030  ? 1280 PHE AAA HD2  1 
ATOM   313  H HE1  . PHE A 1 19  ? -24.957 -1.126  22.822 1.000 43.910  ? 1280 PHE AAA HE1  1 
ATOM   314  H HE2  . PHE A 1 19  ? -21.719 1.179   23.386 1.000 45.750  ? 1280 PHE AAA HE2  1 
ATOM   315  H HZ   . PHE A 1 19  ? -23.098 -0.556  24.082 1.000 40.350  ? 1280 PHE AAA HZ   1 
ATOM   316  N N    . LEU A 1 20  ? -25.063 1.638   16.283 1.000 41.000  ? 1281 LEU AAA N    1 
ATOM   317  C CA   . LEU A 1 20  ? -25.662 2.276   15.075 1.000 38.080  ? 1281 LEU AAA CA   1 
ATOM   318  C C    . LEU A 1 20  ? -27.182 2.217   15.211 1.000 37.620  ? 1281 LEU AAA C    1 
ATOM   319  O O    . LEU A 1 20  ? -27.720 1.089   15.100 1.000 37.200  ? 1281 LEU AAA O    1 
ATOM   320  C CB   . LEU A 1 20  ? -25.204 1.576   13.790 1.000 35.010  ? 1281 LEU AAA CB   1 
ATOM   321  C CG   . LEU A 1 20  ? -23.695 1.437   13.602 1.000 35.620  ? 1281 LEU AAA CG   1 
ATOM   322  C CD1  . LEU A 1 20  ? -23.366 0.516   12.442 1.000 36.260  ? 1281 LEU AAA CD1  1 
ATOM   323  C CD2  . LEU A 1 20  ? -23.013 2.782   13.432 1.000 35.800  ? 1281 LEU AAA CD2  1 
ATOM   324  H H    . LEU A 1 20  ? -25.232 0.658   16.457 1.000 41.000  ? 1281 LEU AAA H    1 
ATOM   325  H HA   . LEU A 1 20  ? -25.373 3.217   15.043 1.000 38.080  ? 1281 LEU AAA HA   1 
ATOM   326  H HB2  . LEU A 1 20  ? -25.597 0.681   13.771 1.000 35.010  ? 1281 LEU AAA HB2  1 
ATOM   327  H HB3  . LEU A 1 20  ? -25.562 2.071   13.026 1.000 35.010  ? 1281 LEU AAA HB3  1 
ATOM   328  H HG   . LEU A 1 20  ? -23.322 1.016   14.416 1.000 35.620  ? 1281 LEU AAA HG   1 
ATOM   329  H HD11 . LEU A 1 20  ? -23.740 -0.366  12.612 1.000 36.260  ? 1281 LEU AAA HD11 1 
ATOM   330  H HD12 . LEU A 1 20  ? -22.400 0.447   12.346 1.000 36.260  ? 1281 LEU AAA HD12 1 
ATOM   331  H HD13 . LEU A 1 20  ? -23.748 0.877   11.623 1.000 36.260  ? 1281 LEU AAA HD13 1 
ATOM   332  H HD21 . LEU A 1 20  ? -23.375 3.233   12.650 1.000 35.800  ? 1281 LEU AAA HD21 1 
ATOM   333  H HD22 . LEU A 1 20  ? -22.056 2.648   13.316 1.000 35.800  ? 1281 LEU AAA HD22 1 
ATOM   334  H HD23 . LEU A 1 20  ? -23.170 3.328   14.222 1.000 35.800  ? 1281 LEU AAA HD23 1 
ATOM   335  N N    . LEU A 1 21  ? -27.802 3.391   15.390 1.000 35.610  ? 1282 LEU AAA N    1 
ATOM   336  C CA   . LEU A 1 21  ? -29.217 3.593   15.785 1.000 39.410  ? 1282 LEU AAA CA   1 
ATOM   337  C C    . LEU A 1 21  ? -30.016 4.048   14.568 1.000 39.490  ? 1282 LEU AAA C    1 
ATOM   338  O O    . LEU A 1 21  ? -29.667 5.100   14.014 1.000 38.890  ? 1282 LEU AAA O    1 
ATOM   339  C CB   . LEU A 1 21  ? -29.300 4.653   16.894 1.000 41.500  ? 1282 LEU AAA CB   1 
ATOM   340  C CG   . LEU A 1 21  ? -28.885 4.191   18.294 1.000 40.010  ? 1282 LEU AAA CG   1 
ATOM   341  C CD1  . LEU A 1 21  ? -27.414 3.847   18.364 1.000 40.680  ? 1282 LEU AAA CD1  1 
ATOM   342  C CD2  . LEU A 1 21  ? -29.217 5.258   19.315 1.000 43.350  ? 1282 LEU AAA CD2  1 
ATOM   343  H H    . LEU A 1 21  ? -27.215 4.198   15.231 1.000 35.610  ? 1282 LEU AAA H    1 
ATOM   344  H HA   . LEU A 1 21  ? -29.579 2.733   16.100 1.000 39.410  ? 1282 LEU AAA HA   1 
ATOM   345  H HB2  . LEU A 1 21  ? -28.733 5.408   16.641 1.000 41.500  ? 1282 LEU AAA HB2  1 
ATOM   346  H HB3  . LEU A 1 21  ? -30.221 4.979   16.940 1.000 41.500  ? 1282 LEU AAA HB3  1 
ATOM   347  H HG   . LEU A 1 21  ? -29.402 3.377   18.514 1.000 40.010  ? 1282 LEU AAA HG   1 
ATOM   348  H HD11 . LEU A 1 21  ? -27.218 3.130   17.736 1.000 40.680  ? 1282 LEU AAA HD11 1 
ATOM   349  H HD12 . LEU A 1 21  ? -27.190 3.560   19.266 1.000 40.680  ? 1282 LEU AAA HD12 1 
ATOM   350  H HD13 . LEU A 1 21  ? -26.886 4.631   18.134 1.000 40.680  ? 1282 LEU AAA HD13 1 
ATOM   351  H HD21 . LEU A 1 21  ? -28.741 6.077   19.095 1.000 43.350  ? 1282 LEU AAA HD21 1 
ATOM   352  H HD22 . LEU A 1 21  ? -28.950 4.954   20.200 1.000 43.350  ? 1282 LEU AAA HD22 1 
ATOM   353  H HD23 . LEU A 1 21  ? -30.175 5.429   19.307 1.000 43.350  ? 1282 LEU AAA HD23 1 
ATOM   354  N N    . ASP A 1 22  ? -31.064 3.299   14.203 1.000 42.060  ? 1283 ASP AAA N    1 
ATOM   355  C CA   . ASP A 1 22  ? -32.027 3.673   13.125 1.000 43.450  ? 1283 ASP AAA CA   1 
ATOM   356  C C    . ASP A 1 22  ? -32.701 4.991   13.528 1.000 44.670  ? 1283 ASP AAA C    1 
ATOM   357  O O    . ASP A 1 22  ? -33.266 5.087   14.665 1.000 44.650  ? 1283 ASP AAA O    1 
ATOM   358  C CB   . ASP A 1 22  ? -33.021 2.541   12.875 1.000 47.020  ? 1283 ASP AAA CB   1 
ATOM   359  C CG   . ASP A 1 22  ? -34.028 2.758   11.749 1.000 47.910  ? 1283 ASP AAA CG   1 
ATOM   360  O OD1  . ASP A 1 22  ? -34.628 3.870   11.651 1.000 43.070  ? 1283 ASP AAA OD1  1 
ATOM   361  O OD2  . ASP A 1 22  ? -34.220 1.788   10.991 1.000 50.570  ? 1283 ASP AAA OD2  1 
ATOM   362  H H    . ASP A 1 22  ? -31.195 2.430   14.700 1.000 42.060  ? 1283 ASP AAA H    1 
ATOM   363  H HA   . ASP A 1 22  ? -31.523 3.805   12.288 1.000 43.450  ? 1283 ASP AAA HA   1 
ATOM   364  H HB2  . ASP A 1 22  ? -32.519 1.733   12.643 1.000 47.020  ? 1283 ASP AAA HB2  1 
ATOM   365  H HB3  . ASP A 1 22  ? -33.546 2.403   13.690 1.000 47.020  ? 1283 ASP AAA HB3  1 
ATOM   366  N N    . GLY A 1 23  ? -32.552 6.001   12.672 1.000 45.740  ? 1284 GLY AAA N    1 
ATOM   367  C CA   . GLY A 1 23  ? -33.160 7.340   12.834 1.000 50.890  ? 1284 GLY AAA CA   1 
ATOM   368  C C    . GLY A 1 23  ? -34.484 7.526   12.079 1.000 48.410  ? 1284 GLY AAA C    1 
ATOM   369  O O    . GLY A 1 23  ? -34.956 8.668   12.101 1.000 53.100  ? 1284 GLY AAA O    1 
ATOM   370  H H    . GLY A 1 23  ? -31.978 5.815   11.862 1.000 45.740  ? 1284 GLY AAA H    1 
ATOM   371  H HA2  . GLY A 1 23  ? -33.328 7.504   13.796 1.000 50.890  ? 1284 GLY AAA HA2  1 
ATOM   372  H HA3  . GLY A 1 23  ? -32.523 8.026   12.512 1.000 50.890  ? 1284 GLY AAA HA3  1 
ATOM   373  N N    . SER A 1 24  ? -35.087 6.487   11.464 1.000 45.690  ? 1285 SER AAA N    1 
ATOM   374  C CA   . SER A 1 24  ? -36.340 6.614   10.669 1.000 48.810  ? 1285 SER AAA CA   1 
ATOM   375  C C    . SER A 1 24  ? -37.565 6.719   11.590 1.000 57.850  ? 1285 SER AAA C    1 
ATOM   376  O O    . SER A 1 24  ? -37.505 6.319   12.809 1.000 56.220  ? 1285 SER AAA O    1 
ATOM   377  C CB   . SER A 1 24  ? -36.518 5.503   9.659  1.000 46.470  ? 1285 SER AAA CB   1 
ATOM   378  O OG   . SER A 1 24  ? -37.035 4.339   10.283 1.000 50.450  ? 1285 SER AAA OG   1 
ATOM   379  H H    . SER A 1 24  ? -34.653 5.580   11.557 1.000 45.690  ? 1285 SER AAA H    1 
ATOM   380  H HA   . SER A 1 24  ? -36.285 7.455   10.140 1.000 48.810  ? 1285 SER AAA HA   1 
ATOM   381  H HB2  . SER A 1 24  ? -37.137 5.800   8.954  1.000 46.470  ? 1285 SER AAA HB2  1 
ATOM   382  H HB3  . SER A 1 24  ? -35.649 5.296   9.246  1.000 46.470  ? 1285 SER AAA HB3  1 
ATOM   383  H HG   . SER A 1 24  ? -37.124 3.736   9.696  0.000 50.450  ? 1285 SER AAA HG   1 
ATOM   384  N N    . SER A 1 25  ? -38.651 7.225   11.000 1.000 57.410  ? 1286 SER AAA N    1 
ATOM   385  C CA   . SER A 1 25  ? -39.994 7.370   11.607 1.000 53.910  ? 1286 SER AAA CA   1 
ATOM   386  C C    . SER A 1 25  ? -40.621 5.988   11.832 1.000 51.030  ? 1286 SER AAA C    1 
ATOM   387  O O    . SER A 1 25  ? -41.702 5.963   12.413 1.000 52.230  ? 1286 SER AAA O    1 
ATOM   388  C CB   . SER A 1 25  ? -40.876 8.234   10.737 1.000 58.080  ? 1286 SER AAA CB   1 
ATOM   389  O OG   . SER A 1 25  ? -41.342 7.495   9.611  1.000 56.200  ? 1286 SER AAA OG   1 
ATOM   390  H H    . SER A 1 25  ? -38.506 7.528   10.048 1.000 57.410  ? 1286 SER AAA H    1 
ATOM   391  H HA   . SER A 1 25  ? -39.886 7.810   12.493 1.000 53.910  ? 1286 SER AAA HA   1 
ATOM   392  H HB2  . SER A 1 25  ? -41.644 8.550   11.265 1.000 58.080  ? 1286 SER AAA HB2  1 
ATOM   393  H HB3  . SER A 1 25  ? -40.364 9.016   10.430 1.000 58.080  ? 1286 SER AAA HB3  1 
ATOM   394  H HG   . SER A 1 25  ? -41.832 8.000   9.142  0.000 56.200  ? 1286 SER AAA HG   1 
ATOM   395  N N    . ARG A 1 26  ? -40.008 4.884   11.373 1.000 51.550  ? 1287 ARG AAA N    1 
ATOM   396  C CA   . ARG A 1 26  ? -40.445 3.514   11.770 1.000 52.350  ? 1287 ARG AAA CA   1 
ATOM   397  C C    . ARG A 1 26  ? -40.443 3.394   13.306 1.000 51.860  ? 1287 ARG AAA C    1 
ATOM   398  O O    . ARG A 1 26  ? -41.191 2.578   13.843 1.000 48.960  ? 1287 ARG AAA O    1 
ATOM   399  C CB   . ARG A 1 26  ? -39.559 2.449   11.124 1.000 59.850  ? 1287 ARG AAA CB   1 
ATOM   400  C CG   . ARG A 1 26  ? -39.705 2.345   9.611  1.000 62.920  ? 1287 ARG AAA CG   1 
ATOM   401  C CD   . ARG A 1 26  ? -41.148 2.115   9.269  1.000 64.700  ? 1287 ARG AAA CD   1 
ATOM   402  N NE   . ARG A 1 26  ? -41.369 1.470   7.990  1.000 69.630  ? 1287 ARG AAA NE   1 
ATOM   403  C CZ   . ARG A 1 26  ? -42.580 1.230   7.496  1.000 74.600  ? 1287 ARG AAA CZ   1 
ATOM   404  N NH1  . ARG A 1 26  ? -43.656 1.573   8.181  1.000 75.190  ? 1287 ARG AAA NH1  1 
ATOM   405  N NH2  . ARG A 1 26  ? -42.721 0.641   6.325  1.000 77.250  ? 1287 ARG AAA NH2  1 
ATOM   406  H H    . ARG A 1 26  ? -39.228 4.988   10.740 1.000 51.550  ? 1287 ARG AAA H    1 
ATOM   407  H HA   . ARG A 1 26  ? -41.364 3.373   11.445 1.000 52.350  ? 1287 ARG AAA HA   1 
ATOM   408  H HB2  . ARG A 1 26  ? -38.624 2.651   11.336 1.000 59.850  ? 1287 ARG AAA HB2  1 
ATOM   409  H HB3  . ARG A 1 26  ? -39.777 1.580   11.521 1.000 59.850  ? 1287 ARG AAA HB3  1 
ATOM   410  H HG2  . ARG A 1 26  ? -39.380 3.173   9.197  1.000 62.920  ? 1287 ARG AAA HG2  1 
ATOM   411  H HG3  . ARG A 1 26  ? -39.151 1.605   9.282  1.000 62.920  ? 1287 ARG AAA HG3  1 
ATOM   412  H HD2  . ARG A 1 26  ? -41.560 1.559   9.965  1.000 64.700  ? 1287 ARG AAA HD2  1 
ATOM   413  H HD3  . ARG A 1 26  ? -41.619 2.976   9.260  1.000 64.700  ? 1287 ARG AAA HD3  1 
ATOM   414  H HE   . ARG A 1 26  ? -40.669 1.231   7.528  1.000 69.630  ? 1287 ARG AAA HE   1 
ATOM   415  H HH11 . ARG A 1 26  ? -43.570 1.961   8.965  1.000 75.190  ? 1287 ARG AAA HH11 1 
ATOM   416  H HH12 . ARG A 1 26  ? -44.455 1.412   7.851  1.000 75.190  ? 1287 ARG AAA HH12 1 
ATOM   417  H HH21 . ARG A 1 26  ? -42.008 0.404   5.865  1.000 77.250  ? 1287 ARG AAA HH21 1 
ATOM   418  H HH22 . ARG A 1 26  ? -43.528 0.486   6.006  1.000 77.250  ? 1287 ARG AAA HH22 1 
ATOM   419  N N    . LEU A 1 27  ? -39.636 4.197   13.996 1.000 49.570  ? 1288 LEU AAA N    1 
ATOM   420  C CA   . LEU A 1 27  ? -39.724 4.383   15.464 1.000 51.910  ? 1288 LEU AAA CA   1 
ATOM   421  C C    . LEU A 1 27  ? -40.406 5.724   15.765 1.000 51.630  ? 1288 LEU AAA C    1 
ATOM   422  O O    . LEU A 1 27  ? -39.956 6.738   15.179 1.000 48.410  ? 1288 LEU AAA O    1 
ATOM   423  C CB   . LEU A 1 27  ? -38.317 4.344   16.081 1.000 50.860  ? 1288 LEU AAA CB   1 
ATOM   424  C CG   . LEU A 1 27  ? -37.518 3.050   15.907 1.000 51.110  ? 1288 LEU AAA CG   1 
ATOM   425  C CD1  . LEU A 1 27  ? -36.131 3.224   16.498 1.000 50.740  ? 1288 LEU AAA CD1  1 
ATOM   426  C CD2  . LEU A 1 27  ? -38.212 1.846   16.537 1.000 46.990  ? 1288 LEU AAA CD2  1 
ATOM   427  H H    . LEU A 1 27  ? -38.930 4.700   13.477 1.000 49.570  ? 1288 LEU AAA H    1 
ATOM   428  H HA   . LEU A 1 27  ? -40.273 3.656   15.839 1.000 51.910  ? 1288 LEU AAA HA   1 
ATOM   429  H HB2  . LEU A 1 27  ? -37.791 5.072   15.694 1.000 50.860  ? 1288 LEU AAA HB2  1 
ATOM   430  H HB3  . LEU A 1 27  ? -38.397 4.517   17.040 1.000 50.860  ? 1288 LEU AAA HB3  1 
ATOM   431  H HG   . LEU A 1 27  ? -37.436 2.868   14.938 1.000 51.110  ? 1288 LEU AAA HG   1 
ATOM   432  H HD11 . LEU A 1 27  ? -35.673 3.951   16.042 1.000 50.740  ? 1288 LEU AAA HD11 1 
ATOM   433  H HD12 . LEU A 1 27  ? -35.625 2.400   16.387 1.000 50.740  ? 1288 LEU AAA HD12 1 
ATOM   434  H HD13 . LEU A 1 27  ? -36.206 3.433   17.445 1.000 50.740  ? 1288 LEU AAA HD13 1 
ATOM   435  H HD21 . LEU A 1 27  ? -38.329 2.001   17.490 1.000 46.990  ? 1288 LEU AAA HD21 1 
ATOM   436  H HD22 . LEU A 1 27  ? -37.669 1.050   16.401 1.000 46.990  ? 1288 LEU AAA HD22 1 
ATOM   437  H HD23 . LEU A 1 27  ? -39.082 1.719   16.121 1.000 46.990  ? 1288 LEU AAA HD23 1 
ATOM   438  N N    . SER A 1 28  ? -41.411 5.729   16.657 1.000 50.090  ? 1289 SER AAA N    1 
ATOM   439  C CA   . SER A 1 28  ? -41.941 6.952   17.315 1.000 54.730  ? 1289 SER AAA CA   1 
ATOM   440  C C    . SER A 1 28  ? -40.839 7.584   18.176 1.000 55.660  ? 1289 SER AAA C    1 
ATOM   441  O O    . SER A 1 28  ? -39.933 6.857   18.611 1.000 60.450  ? 1289 SER AAA O    1 
ATOM   442  C CB   . SER A 1 28  ? -43.153 6.620   18.158 1.000 58.640  ? 1289 SER AAA CB   1 
ATOM   443  O OG   . SER A 1 28  ? -42.876 5.538   19.043 1.000 58.800  ? 1289 SER AAA OG   1 
ATOM   444  H H    . SER A 1 28  ? -41.819 4.833   16.881 1.000 50.090  ? 1289 SER AAA H    1 
ATOM   445  H HA   . SER A 1 28  ? -42.196 7.599   16.603 1.000 54.730  ? 1289 SER AAA HA   1 
ATOM   446  H HB2  . SER A 1 28  ? -43.412 7.412   18.682 1.000 58.640  ? 1289 SER AAA HB2  1 
ATOM   447  H HB3  . SER A 1 28  ? -43.902 6.376   17.569 1.000 58.640  ? 1289 SER AAA HB3  1 
ATOM   448  H HG   . SER A 1 28  ? -43.571 5.378   19.498 0.000 58.800  ? 1289 SER AAA HG   1 
ATOM   449  N N    . GLU A 1 29  ? -40.948 8.870   18.492 1.000 56.150  ? 1290 GLU AAA N    1 
ATOM   450  C CA   . GLU A 1 29  ? -40.093 9.527   19.518 1.000 61.040  ? 1290 GLU AAA CA   1 
ATOM   451  C C    . GLU A 1 29  ? -39.995 8.670   20.798 1.000 61.660  ? 1290 GLU AAA C    1 
ATOM   452  O O    . GLU A 1 29  ? -38.901 8.514   21.313 1.000 58.810  ? 1290 GLU AAA O    1 
ATOM   453  C CB   . GLU A 1 29  ? -40.658 10.890  19.877 1.000 61.920  ? 1290 GLU AAA CB   1 
ATOM   454  C CG   . GLU A 1 29  ? -39.694 11.729  20.667 1.000 69.550  ? 1290 GLU AAA CG   1 
ATOM   455  C CD   . GLU A 1 29  ? -39.888 13.225  20.477 1.000 92.320  ? 1290 GLU AAA CD   1 
ATOM   456  O OE1  . GLU A 1 29  ? -40.444 13.643  19.419 1.000 96.670  ? 1290 GLU AAA OE1  1 
ATOM   457  O OE2  . GLU A 1 29  ? -39.477 13.978  21.384 1.000 102.460 ? 1290 GLU AAA OE2  1 
ATOM   458  H H    . GLU A 1 29  ? -41.646 9.417   18.008 1.000 56.150  ? 1290 GLU AAA H    1 
ATOM   459  H HA   . GLU A 1 29  ? -39.184 9.626   19.151 1.000 61.040  ? 1290 GLU AAA HA   1 
ATOM   460  H HB2  . GLU A 1 29  ? -40.891 11.359  19.049 1.000 61.920  ? 1290 GLU AAA HB2  1 
ATOM   461  H HB3  . GLU A 1 29  ? -41.477 10.760  20.400 1.000 61.920  ? 1290 GLU AAA HB3  1 
ATOM   462  H HG2  . GLU A 1 29  ? -39.792 11.514  21.619 1.000 69.550  ? 1290 GLU AAA HG2  1 
ATOM   463  H HG3  . GLU A 1 29  ? -38.779 11.492  20.406 1.000 69.550  ? 1290 GLU AAA HG3  1 
ATOM   464  N N    . ALA A 1 30  ? -41.097 8.119   21.295 1.000 56.160  ? 1291 ALA AAA N    1 
ATOM   465  C CA   . ALA A 1 30  ? -41.132 7.309   22.536 1.000 59.110  ? 1291 ALA AAA CA   1 
ATOM   466  C C    . ALA A 1 30  ? -40.373 5.981   22.351 1.000 54.950  ? 1291 ALA AAA C    1 
ATOM   467  O O    . ALA A 1 30  ? -39.629 5.587   23.245 1.000 49.870  ? 1291 ALA AAA O    1 
ATOM   468  C CB   . ALA A 1 30  ? -42.572 7.078   22.932 1.000 57.120  ? 1291 ALA AAA CB   1 
ATOM   469  H H    . ALA A 1 30  ? -41.954 8.272   20.783 1.000 56.160  ? 1291 ALA AAA H    1 
ATOM   470  H HA   . ALA A 1 30  ? -40.685 7.816   23.254 1.000 59.110  ? 1291 ALA AAA HA   1 
ATOM   471  H HB1  . ALA A 1 30  ? -42.604 6.548   23.744 1.000 57.120  ? 1291 ALA AAA HB1  1 
ATOM   472  H HB2  . ALA A 1 30  ? -43.007 7.931   23.087 1.000 57.120  ? 1291 ALA AAA HB2  1 
ATOM   473  H HB3  . ALA A 1 30  ? -43.033 6.605   22.219 1.000 57.120  ? 1291 ALA AAA HB3  1 
ATOM   474  N N    . GLU A 1 31  ? -40.566 5.309   21.219 1.000 58.400  ? 1292 GLU AAA N    1 
ATOM   475  C CA   . GLU A 1 31  ? -39.819 4.084   20.857 1.000 54.730  ? 1292 GLU AAA CA   1 
ATOM   476  C C    . GLU A 1 31  ? -38.322 4.382   20.703 1.000 51.780  ? 1292 GLU AAA C    1 
ATOM   477  O O    . GLU A 1 31  ? -37.546 3.498   21.044 1.000 52.700  ? 1292 GLU AAA O    1 
ATOM   478  C CB   . GLU A 1 31  ? -40.380 3.474   19.577 1.000 59.820  ? 1292 GLU AAA CB   1 
ATOM   479  C CG   . GLU A 1 31  ? -41.730 2.817   19.772 1.000 57.200  ? 1292 GLU AAA CG   1 
ATOM   480  C CD   . GLU A 1 31  ? -42.417 2.463   18.471 1.000 57.650  ? 1292 GLU AAA CD   1 
ATOM   481  O OE1  . GLU A 1 31  ? -42.024 3.017   17.438 1.000 56.700  ? 1292 GLU AAA OE1  1 
ATOM   482  O OE2  . GLU A 1 31  ? -43.355 1.659   18.505 1.000 54.800  ? 1292 GLU AAA OE2  1 
ATOM   483  H H    . GLU A 1 31  ? -41.264 5.667   20.582 1.000 58.400  ? 1292 GLU AAA H    1 
ATOM   484  H HA   . GLU A 1 31  ? -39.926 3.427   21.583 1.000 54.730  ? 1292 GLU AAA HA   1 
ATOM   485  H HB2  . GLU A 1 31  ? -40.463 4.182   18.905 1.000 59.820  ? 1292 GLU AAA HB2  1 
ATOM   486  H HB3  . GLU A 1 31  ? -39.744 2.806   19.245 1.000 59.820  ? 1292 GLU AAA HB3  1 
ATOM   487  H HG2  . GLU A 1 31  ? -41.613 2.002   20.305 1.000 57.200  ? 1292 GLU AAA HG2  1 
ATOM   488  H HG3  . GLU A 1 31  ? -42.307 3.422   20.285 1.000 57.200  ? 1292 GLU AAA HG3  1 
ATOM   489  N N    . PHE A 1 32  ? -37.916 5.560   20.224 1.000 51.770  ? 1293 PHE AAA N    1 
ATOM   490  C CA   . PHE A 1 32  ? -36.478 5.896   20.026 1.000 47.900  ? 1293 PHE AAA CA   1 
ATOM   491  C C    . PHE A 1 32  ? -35.809 6.077   21.392 1.000 48.360  ? 1293 PHE AAA C    1 
ATOM   492  O O    . PHE A 1 32  ? -34.671 5.596   21.567 1.000 52.200  ? 1293 PHE AAA O    1 
ATOM   493  C CB   . PHE A 1 32  ? -36.305 7.120   19.128 1.000 47.600  ? 1293 PHE AAA CB   1 
ATOM   494  C CG   . PHE A 1 32  ? -34.881 7.431   18.724 1.000 45.360  ? 1293 PHE AAA CG   1 
ATOM   495  C CD1  . PHE A 1 32  ? -34.194 6.623   17.830 1.000 52.160  ? 1293 PHE AAA CD1  1 
ATOM   496  C CD2  . PHE A 1 32  ? -34.224 8.545   19.221 1.000 45.700  ? 1293 PHE AAA CD2  1 
ATOM   497  C CE1  . PHE A 1 32  ? -32.888 6.909   17.454 1.000 48.680  ? 1293 PHE AAA CE1  1 
ATOM   498  C CE2  . PHE A 1 32  ? -32.918 8.829   18.857 1.000 45.720  ? 1293 PHE AAA CE2  1 
ATOM   499  C CZ   . PHE A 1 32  ? -32.247 8.003   17.983 1.000 51.640  ? 1293 PHE AAA CZ   1 
ATOM   500  H H    . PHE A 1 32  ? -38.619 6.246   19.989 1.000 51.770  ? 1293 PHE AAA H    1 
ATOM   501  H HA   . PHE A 1 32  ? -36.039 5.141   19.557 1.000 47.900  ? 1293 PHE AAA HA   1 
ATOM   502  H HB2  . PHE A 1 32  ? -36.837 6.986   18.316 1.000 47.600  ? 1293 PHE AAA HB2  1 
ATOM   503  H HB3  . PHE A 1 32  ? -36.674 7.900   19.592 1.000 47.600  ? 1293 PHE AAA HB3  1 
ATOM   504  H HD1  . PHE A 1 32  ? -34.620 5.864   17.465 1.000 52.160  ? 1293 PHE AAA HD1  1 
ATOM   505  H HD2  . PHE A 1 32  ? -34.679 9.117   19.818 1.000 45.700  ? 1293 PHE AAA HD2  1 
ATOM   506  H HE1  . PHE A 1 32  ? -32.441 6.344   16.844 1.000 48.680  ? 1293 PHE AAA HE1  1 
ATOM   507  H HE2  . PHE A 1 32  ? -32.481 9.582   19.222 1.000 45.720  ? 1293 PHE AAA HE2  1 
ATOM   508  H HZ   . PHE A 1 32  ? -31.359 8.198   17.728 1.000 51.640  ? 1293 PHE AAA HZ   1 
ATOM   509  N N    . GLU A 1 33  ? -36.507 6.709   22.336 1.000 50.730  ? 1294 GLU AAA N    1 
ATOM   510  C CA   . GLU A 1 33  ? -36.104 6.878   23.765 1.000 50.670  ? 1294 GLU AAA CA   1 
ATOM   511  C C    . GLU A 1 33  ? -35.830 5.504   24.407 1.000 48.800  ? 1294 GLU AAA C    1 
ATOM   512  O O    . GLU A 1 33  ? -34.843 5.370   25.139 1.000 47.630  ? 1294 GLU AAA O    1 
ATOM   513  C CB   . GLU A 1 33  ? -37.196 7.615   24.551 1.000 50.770  ? 1294 GLU AAA CB   1 
ATOM   514  C CG   . GLU A 1 33  ? -37.189 9.126   24.359 1.000 55.370  ? 1294 GLU AAA CG   1 
ATOM   515  C CD   . GLU A 1 33  ? -35.795 9.729   24.390 1.000 63.510  ? 1294 GLU AAA CD   1 
ATOM   516  O OE1  . GLU A 1 33  ? -35.225 9.811   25.491 1.000 62.990  ? 1294 GLU AAA OE1  1 
ATOM   517  O OE2  . GLU A 1 33  ? -35.239 10.030  23.304 1.000 62.720  ? 1294 GLU AAA OE2  1 
ATOM   518  H H    . GLU A 1 33  ? -37.385 7.098   22.023 1.000 50.730  ? 1294 GLU AAA H    1 
ATOM   519  H HA   . GLU A 1 33  ? -35.273 7.406   23.795 1.000 50.670  ? 1294 GLU AAA HA   1 
ATOM   520  H HB2  . GLU A 1 33  ? -38.069 7.269   24.271 1.000 50.770  ? 1294 GLU AAA HB2  1 
ATOM   521  H HB3  . GLU A 1 33  ? -37.078 7.422   25.504 1.000 50.770  ? 1294 GLU AAA HB3  1 
ATOM   522  H HG2  . GLU A 1 33  ? -37.612 9.339   23.500 1.000 55.370  ? 1294 GLU AAA HG2  1 
ATOM   523  H HG3  . GLU A 1 33  ? -37.733 9.538   25.063 1.000 55.370  ? 1294 GLU AAA HG3  1 
ATOM   524  N N    . VAL A 1 34  ? -36.677 4.515   24.133 1.000 49.280  ? 1295 VAL AAA N    1 
ATOM   525  C CA   . VAL A 1 34  ? -36.491 3.106   24.578 1.000 49.070  ? 1295 VAL AAA CA   1 
ATOM   526  C C    . VAL A 1 34  ? -35.190 2.563   23.969 1.000 49.220  ? 1295 VAL AAA C    1 
ATOM   527  O O    . VAL A 1 34  ? -34.429 1.920   24.705 1.000 53.510  ? 1295 VAL AAA O    1 
ATOM   528  C CB   . VAL A 1 34  ? -37.705 2.243   24.197 1.000 49.150  ? 1295 VAL AAA CB   1 
ATOM   529  C CG1  . VAL A 1 34  ? -37.463 0.780   24.520 1.000 47.990  ? 1295 VAL AAA CG1  1 
ATOM   530  C CG2  . VAL A 1 34  ? -38.982 2.750   24.852 1.000 47.270  ? 1295 VAL AAA CG2  1 
ATOM   531  H H    . VAL A 1 34  ? -37.492 4.756   23.587 1.000 49.280  ? 1295 VAL AAA H    1 
ATOM   532  H HA   . VAL A 1 34  ? -36.405 3.099   25.548 1.000 49.070  ? 1295 VAL AAA HA   1 
ATOM   533  H HB   . VAL A 1 34  ? -37.821 2.316   23.218 1.000 49.150  ? 1295 VAL AAA HB   1 
ATOM   534  H HG11 . VAL A 1 34  ? -36.689 0.462   24.024 1.000 47.990  ? 1295 VAL AAA HG11 1 
ATOM   535  H HG12 . VAL A 1 34  ? -38.245 0.258   24.270 1.000 47.990  ? 1295 VAL AAA HG12 1 
ATOM   536  H HG13 . VAL A 1 34  ? -37.300 0.681   25.474 1.000 47.990  ? 1295 VAL AAA HG13 1 
ATOM   537  H HG21 . VAL A 1 34  ? -38.882 2.728   25.820 1.000 47.270  ? 1295 VAL AAA HG21 1 
ATOM   538  H HG22 . VAL A 1 34  ? -39.728 2.183   24.590 1.000 47.270  ? 1295 VAL AAA HG22 1 
ATOM   539  H HG23 . VAL A 1 34  ? -39.154 3.664   24.565 1.000 47.270  ? 1295 VAL AAA HG23 1 
ATOM   540  N N    . LEU A 1 35  ? -34.925 2.818   22.683 1.000 52.250  ? 1296 LEU AAA N    1 
ATOM   541  C CA   . LEU A 1 35  ? -33.674 2.357   22.003 1.000 48.700  ? 1296 LEU AAA CA   1 
ATOM   542  C C    . LEU A 1 35  ? -32.446 2.995   22.684 1.000 47.150  ? 1296 LEU AAA C    1 
ATOM   543  O O    . LEU A 1 35  ? -31.479 2.285   22.966 1.000 40.480  ? 1296 LEU AAA O    1 
ATOM   544  C CB   . LEU A 1 35  ? -33.722 2.716   20.518 1.000 47.370  ? 1296 LEU AAA CB   1 
ATOM   545  C CG   . LEU A 1 35  ? -32.540 2.219   19.684 1.000 48.090  ? 1296 LEU AAA CG   1 
ATOM   546  C CD1  . LEU A 1 35  ? -32.268 0.738   19.904 1.000 49.500  ? 1296 LEU AAA CD1  1 
ATOM   547  C CD2  . LEU A 1 35  ? -32.773 2.475   18.210 1.000 52.360  ? 1296 LEU AAA CD2  1 
ATOM   548  H H    . LEU A 1 35  ? -35.606 3.346   22.156 1.000 52.250  ? 1296 LEU AAA H    1 
ATOM   549  H HA   . LEU A 1 35  ? -33.611 1.378   22.095 1.000 48.700  ? 1296 LEU AAA HA   1 
ATOM   550  H HB2  . LEU A 1 35  ? -34.545 2.348   20.139 1.000 47.370  ? 1296 LEU AAA HB2  1 
ATOM   551  H HB3  . LEU A 1 35  ? -33.770 3.690   20.438 1.000 47.370  ? 1296 LEU AAA HB3  1 
ATOM   552  H HG   . LEU A 1 35  ? -31.736 2.725   19.959 1.000 48.090  ? 1296 LEU AAA HG   1 
ATOM   553  H HD11 . LEU A 1 35  ? -32.065 0.581   20.843 1.000 49.500  ? 1296 LEU AAA HD11 1 
ATOM   554  H HD12 . LEU A 1 35  ? -31.512 0.462   19.357 1.000 49.500  ? 1296 LEU AAA HD12 1 
ATOM   555  H HD13 . LEU A 1 35  ? -33.054 0.223   19.653 1.000 49.500  ? 1296 LEU AAA HD13 1 
ATOM   556  H HD21 . LEU A 1 35  ? -33.577 2.009   17.923 1.000 52.360  ? 1296 LEU AAA HD21 1 
ATOM   557  H HD22 . LEU A 1 35  ? -32.010 2.152   17.700 1.000 52.360  ? 1296 LEU AAA HD22 1 
ATOM   558  H HD23 . LEU A 1 35  ? -32.882 3.430   18.060 1.000 52.360  ? 1296 LEU AAA HD23 1 
ATOM   559  N N    . LYS A 1 36  ? -32.489 4.284   22.999 1.000 42.760  ? 1297 LYS AAA N    1 
ATOM   560  C CA   . LYS A 1 36  ? -31.334 4.967   23.628 1.000 41.680  ? 1297 LYS AAA CA   1 
ATOM   561  C C    . LYS A 1 36  ? -31.108 4.390   25.036 1.000 46.940  ? 1297 LYS AAA C    1 
ATOM   562  O O    . LYS A 1 36  ? -29.939 4.117   25.403 1.000 40.720  ? 1297 LYS AAA O    1 
ATOM   563  C CB   . LYS A 1 36  ? -31.563 6.479   23.659 1.000 41.340  ? 1297 LYS AAA CB   1 
ATOM   564  C CG   . LYS A 1 36  ? -31.872 7.123   22.319 1.000 44.070  ? 1297 LYS AAA CG   1 
ATOM   565  C CD   . LYS A 1 36  ? -31.811 8.623   22.325 1.000 47.320  ? 1297 LYS AAA CD   1 
ATOM   566  C CE   . LYS A 1 36  ? -32.298 9.244   23.608 1.000 51.470  ? 1297 LYS AAA CE   1 
ATOM   567  N NZ   . LYS A 1 36  ? -32.505 10.696  23.445 1.000 54.080  ? 1297 LYS AAA NZ   1 
ATOM   568  H H    . LYS A 1 36  ? -33.328 4.812   22.806 1.000 42.760  ? 1297 LYS AAA H    1 
ATOM   569  H HA   . LYS A 1 36  ? -30.533 4.794   23.081 1.000 41.680  ? 1297 LYS AAA HA   1 
ATOM   570  H HB2  . LYS A 1 36  ? -32.302 6.670   24.274 1.000 41.340  ? 1297 LYS AAA HB2  1 
ATOM   571  H HB3  . LYS A 1 36  ? -30.765 6.908   24.033 1.000 41.340  ? 1297 LYS AAA HB3  1 
ATOM   572  H HG2  . LYS A 1 36  ? -31.229 6.791   21.657 1.000 44.070  ? 1297 LYS AAA HG2  1 
ATOM   573  H HG3  . LYS A 1 36  ? -32.774 6.853   22.042 1.000 44.070  ? 1297 LYS AAA HG3  1 
ATOM   574  H HD2  . LYS A 1 36  ? -30.884 8.906   22.173 1.000 47.320  ? 1297 LYS AAA HD2  1 
ATOM   575  H HD3  . LYS A 1 36  ? -32.355 8.968   21.585 1.000 47.320  ? 1297 LYS AAA HD3  1 
ATOM   576  H HE2  . LYS A 1 36  ? -33.138 8.825   23.876 1.000 51.470  ? 1297 LYS AAA HE2  1 
ATOM   577  H HE3  . LYS A 1 36  ? -31.645 9.087   24.316 1.000 51.470  ? 1297 LYS AAA HE3  1 
ATOM   578  H HZ1  . LYS A 1 36  ? -31.725 11.092  23.207 1.000 54.080  ? 1297 LYS AAA HZ1  1 
ATOM   579  H HZ2  . LYS A 1 36  ? -32.800 11.053  24.225 1.000 54.080  ? 1297 LYS AAA HZ2  1 
ATOM   580  H HZ3  . LYS A 1 36  ? -33.122 10.847  22.798 1.000 54.080  ? 1297 LYS AAA HZ3  1 
ATOM   581  N N    . ALA A 1 37  ? -32.184 4.189   25.797 1.000 43.460  ? 1298 ALA AAA N    1 
ATOM   582  C CA   . ALA A 1 37  ? -32.112 3.616   27.147 1.000 42.580  ? 1298 ALA AAA CA   1 
ATOM   583  C C    . ALA A 1 37  ? -31.362 2.281   27.069 1.000 45.560  ? 1298 ALA AAA C    1 
ATOM   584  O O    . ALA A 1 37  ? -30.475 2.042   27.902 1.000 56.070  ? 1298 ALA AAA O    1 
ATOM   585  C CB   . ALA A 1 37  ? -33.498 3.473   27.698 1.000 39.270  ? 1298 ALA AAA CB   1 
ATOM   586  H H    . ALA A 1 37  ? -33.084 4.446   25.418 1.000 43.460  ? 1298 ALA AAA H    1 
ATOM   587  H HA   . ALA A 1 37  ? -31.607 4.236   27.724 1.000 42.580  ? 1298 ALA AAA HA   1 
ATOM   588  H HB1  . ALA A 1 37  ? -33.455 3.095   28.590 1.000 39.270  ? 1298 ALA AAA HB1  1 
ATOM   589  H HB2  . ALA A 1 37  ? -33.923 4.344   27.738 1.000 39.270  ? 1298 ALA AAA HB2  1 
ATOM   590  H HB3  . ALA A 1 37  ? -34.018 2.886   27.123 1.000 39.270  ? 1298 ALA AAA HB3  1 
ATOM   591  N N    . PHE A 1 38  ? -31.693 1.432   26.104 1.000 39.440  ? 1299 PHE AAA N    1 
ATOM   592  C CA   . PHE A 1 38  ? -31.010 0.129   25.897 1.000 39.510  ? 1299 PHE AAA CA   1 
ATOM   593  C C    . PHE A 1 38  ? -29.520 0.394   25.701 1.000 44.010  ? 1299 PHE AAA C    1 
ATOM   594  O O    . PHE A 1 38  ? -28.647 -0.276  26.303 1.000 40.420  ? 1299 PHE AAA O    1 
ATOM   595  C CB   . PHE A 1 38  ? -31.568 -0.588  24.674 1.000 39.530  ? 1299 PHE AAA CB   1 
ATOM   596  C CG   . PHE A 1 38  ? -30.674 -1.670  24.125 1.000 42.060  ? 1299 PHE AAA CG   1 
ATOM   597  C CD1  . PHE A 1 38  ? -30.676 -2.935  24.687 1.000 38.670  ? 1299 PHE AAA CD1  1 
ATOM   598  C CD2  . PHE A 1 38  ? -29.859 -1.445  23.029 1.000 39.250  ? 1299 PHE AAA CD2  1 
ATOM   599  C CE1  . PHE A 1 38  ? -29.883 -3.944  24.164 1.000 39.580  ? 1299 PHE AAA CE1  1 
ATOM   600  C CE2  . PHE A 1 38  ? -29.040 -2.451  22.527 1.000 44.520  ? 1299 PHE AAA CE2  1 
ATOM   601  C CZ   . PHE A 1 38  ? -29.045 -3.699  23.105 1.000 41.410  ? 1299 PHE AAA CZ   1 
ATOM   602  H H    . PHE A 1 38  ? -32.448 1.696   25.487 1.000 39.440  ? 1299 PHE AAA H    1 
ATOM   603  H HA   . PHE A 1 38  ? -31.135 -0.426  26.709 1.000 39.510  ? 1299 PHE AAA HA   1 
ATOM   604  H HB2  . PHE A 1 38  ? -32.434 -0.979  24.913 1.000 39.530  ? 1299 PHE AAA HB2  1 
ATOM   605  H HB3  . PHE A 1 38  ? -31.733 0.077   23.973 1.000 39.530  ? 1299 PHE AAA HB3  1 
ATOM   606  H HD1  . PHE A 1 38  ? -31.242 -3.119  25.419 1.000 38.670  ? 1299 PHE AAA HD1  1 
ATOM   607  H HD2  . PHE A 1 38  ? -29.862 -0.595  22.619 1.000 39.250  ? 1299 PHE AAA HD2  1 
ATOM   608  H HE1  . PHE A 1 38  ? -29.895 -4.802  24.558 1.000 39.580  ? 1299 PHE AAA HE1  1 
ATOM   609  H HE2  . PHE A 1 38  ? -28.467 -2.273  21.798 1.000 44.520  ? 1299 PHE AAA HE2  1 
ATOM   610  H HZ   . PHE A 1 38  ? -28.509 -4.394  22.757 1.000 41.410  ? 1299 PHE AAA HZ   1 
ATOM   611  N N    . VAL A 1 39  ? -29.218 1.384   24.865 1.000 42.520  ? 1300 VAL AAA N    1 
ATOM   612  C CA   . VAL A 1 39  ? -27.810 1.732   24.562 1.000 40.700  ? 1300 VAL AAA CA   1 
ATOM   613  C C    . VAL A 1 39  ? -27.147 2.169   25.876 1.000 38.700  ? 1300 VAL AAA C    1 
ATOM   614  O O    . VAL A 1 39  ? -26.038 1.721   26.134 1.000 44.250  ? 1300 VAL AAA O    1 
ATOM   615  C CB   . VAL A 1 39  ? -27.717 2.771   23.432 1.000 39.770  ? 1300 VAL AAA CB   1 
ATOM   616  C CG1  . VAL A 1 39  ? -26.298 3.330   23.279 1.000 38.350  ? 1300 VAL AAA CG1  1 
ATOM   617  C CG2  . VAL A 1 39  ? -28.203 2.144   22.141 1.000 38.370  ? 1300 VAL AAA CG2  1 
ATOM   618  H H    . VAL A 1 39  ? -29.961 1.910   24.427 1.000 42.520  ? 1300 VAL AAA H    1 
ATOM   619  H HA   . VAL A 1 39  ? -27.361 0.934   24.229 1.000 40.700  ? 1300 VAL AAA HA   1 
ATOM   620  H HB   . VAL A 1 39  ? -28.319 3.518   23.670 1.000 39.770  ? 1300 VAL AAA HB   1 
ATOM   621  H HG11 . VAL A 1 39  ? -26.027 3.759   24.109 1.000 38.350  ? 1300 VAL AAA HG11 1 
ATOM   622  H HG12 . VAL A 1 39  ? -26.281 3.981   22.556 1.000 38.350  ? 1300 VAL AAA HG12 1 
ATOM   623  H HG13 . VAL A 1 39  ? -25.683 2.604   23.074 1.000 38.350  ? 1300 VAL AAA HG13 1 
ATOM   624  H HG21 . VAL A 1 39  ? -27.648 1.374   21.925 1.000 38.370  ? 1300 VAL AAA HG21 1 
ATOM   625  H HG22 . VAL A 1 39  ? -28.147 2.797   21.422 1.000 38.370  ? 1300 VAL AAA HG22 1 
ATOM   626  H HG23 . VAL A 1 39  ? -29.127 1.857   22.247 1.000 38.370  ? 1300 VAL AAA HG23 1 
ATOM   627  N N    . VAL A 1 40  ? -27.802 2.977   26.702 1.000 41.650  ? 1301 VAL AAA N    1 
ATOM   628  C CA   . VAL A 1 40  ? -27.199 3.477   27.973 1.000 46.330  ? 1301 VAL AAA CA   1 
ATOM   629  C C    . VAL A 1 40  ? -27.050 2.318   28.980 1.000 46.480  ? 1301 VAL AAA C    1 
ATOM   630  O O    . VAL A 1 40  ? -26.013 2.289   29.651 1.000 46.550  ? 1301 VAL AAA O    1 
ATOM   631  C CB   . VAL A 1 40  ? -28.012 4.635   28.564 1.000 48.460  ? 1301 VAL AAA CB   1 
ATOM   632  C CG1  . VAL A 1 40  ? -27.570 4.930   29.986 1.000 47.210  ? 1301 VAL AAA CG1  1 
ATOM   633  C CG2  . VAL A 1 40  ? -27.926 5.871   27.683 1.000 54.230  ? 1301 VAL AAA CG2  1 
ATOM   634  H H    . VAL A 1 40  ? -28.740 3.260   26.457 1.000 41.650  ? 1301 VAL AAA H    1 
ATOM   635  H HA   . VAL A 1 40  ? -26.309 3.820   27.777 1.000 46.330  ? 1301 VAL AAA HA   1 
ATOM   636  H HB   . VAL A 1 40  ? -28.957 4.346   28.591 1.000 48.460  ? 1301 VAL AAA HB   1 
ATOM   637  H HG11 . VAL A 1 40  ? -27.702 4.139   30.538 1.000 47.210  ? 1301 VAL AAA HG11 1 
ATOM   638  H HG12 . VAL A 1 40  ? -28.096 5.667   30.343 1.000 47.210  ? 1301 VAL AAA HG12 1 
ATOM   639  H HG13 . VAL A 1 40  ? -26.628 5.174   29.990 1.000 47.210  ? 1301 VAL AAA HG13 1 
ATOM   640  H HG21 . VAL A 1 40  ? -26.997 6.151   27.606 1.000 54.230  ? 1301 VAL AAA HG21 1 
ATOM   641  H HG22 . VAL A 1 40  ? -28.449 6.589   28.079 1.000 54.230  ? 1301 VAL AAA HG22 1 
ATOM   642  H HG23 . VAL A 1 40  ? -28.276 5.665   26.799 1.000 54.230  ? 1301 VAL AAA HG23 1 
ATOM   643  N N    . ASP A 1 41  ? -28.008 1.383   29.046 1.000 43.410  ? 1302 ASP AAA N    1 
ATOM   644  C CA   . ASP A 1 41  ? -27.916 0.172   29.903 1.000 44.720  ? 1302 ASP AAA CA   1 
ATOM   645  C C    . ASP A 1 41  ? -26.702 -0.644  29.471 1.000 44.470  ? 1302 ASP AAA C    1 
ATOM   646  O O    . ASP A 1 41  ? -25.905 -1.022  30.336 1.000 40.360  ? 1302 ASP AAA O    1 
ATOM   647  C CB   . ASP A 1 41  ? -29.155 -0.722  29.831 1.000 49.440  ? 1302 ASP AAA CB   1 
ATOM   648  C CG   . ASP A 1 41  ? -30.412 -0.064  30.372 1.000 49.780  ? 1302 ASP AAA CG   1 
ATOM   649  O OD1  . ASP A 1 41  ? -30.246 0.940   31.036 1.000 46.690  ? 1302 ASP AAA OD1  1 
ATOM   650  O OD2  . ASP A 1 41  ? -31.549 -0.540  30.076 1.000 56.910  ? 1302 ASP AAA OD2  1 
ATOM   651  H H    . ASP A 1 41  ? -28.831 1.522   28.477 1.000 43.410  ? 1302 ASP AAA H    1 
ATOM   652  H HA   . ASP A 1 41  ? -27.794 0.459   30.838 1.000 44.720  ? 1302 ASP AAA HA   1 
ATOM   653  H HB2  . ASP A 1 41  ? -29.318 -0.951  28.893 1.000 49.440  ? 1302 ASP AAA HB2  1 
ATOM   654  H HB3  . ASP A 1 41  ? -28.988 -1.527  30.362 1.000 49.440  ? 1302 ASP AAA HB3  1 
ATOM   655  N N    . MET A 1 42  ? -26.552 -0.874  28.174 1.000 46.160  ? 1303 MET AAA N    1 
ATOM   656  C CA   . MET A 1 42  ? -25.390 -1.609  27.630 1.000 45.470  ? 1303 MET AAA CA   1 
ATOM   657  C C    . MET A 1 42  ? -24.124 -0.916  28.112 1.000 45.210  ? 1303 MET AAA C    1 
ATOM   658  O O    . MET A 1 42  ? -23.252 -1.589  28.663 1.000 46.110  ? 1303 MET AAA O    1 
ATOM   659  C CB   . MET A 1 42  ? -25.408 -1.617  26.109 1.000 48.450  ? 1303 MET AAA CB   1 
ATOM   660  C CG   . MET A 1 42  ? -26.560 -2.410  25.534 1.000 60.350  ? 1303 MET AAA CG   1 
ATOM   661  S SD   . MET A 1 42  ? -26.333 -4.195  25.757 1.000 61.700  ? 1303 MET AAA SD   1 
ATOM   662  C CE   . MET A 1 42  ? -25.023 -4.459  24.557 1.000 58.660  ? 1303 MET AAA CE   1 
ATOM   663  H H    . MET A 1 42  ? -27.260 -0.533  27.539 1.000 46.160  ? 1303 MET AAA H    1 
ATOM   664  H HA   . MET A 1 42  ? -25.411 -2.530  27.979 1.000 45.470  ? 1303 MET AAA HA   1 
ATOM   665  H HB2  . MET A 1 42  ? -25.464 -0.694  25.792 1.000 48.450  ? 1303 MET AAA HB2  1 
ATOM   666  H HB3  . MET A 1 42  ? -24.566 -1.996  25.788 1.000 48.450  ? 1303 MET AAA HB3  1 
ATOM   667  H HG2  . MET A 1 42  ? -27.393 -2.134  25.973 1.000 60.350  ? 1303 MET AAA HG2  1 
ATOM   668  H HG3  . MET A 1 42  ? -26.642 -2.213  24.577 1.000 60.350  ? 1303 MET AAA HG3  1 
ATOM   669  H HE1  . MET A 1 42  ? -24.778 -5.387  24.550 1.000 58.660  ? 1303 MET AAA HE1  1 
ATOM   670  H HE2  . MET A 1 42  ? -25.332 -4.203  23.685 1.000 58.660  ? 1303 MET AAA HE2  1 
ATOM   671  H HE3  . MET A 1 42  ? -24.256 -3.925  24.797 1.000 58.660  ? 1303 MET AAA HE3  1 
ATOM   672  N N    . MET A 1 43  ? -24.040 0.396   27.952 1.000 45.200  ? 1304 MET AAA N    1 
ATOM   673  C CA   . MET A 1 43  ? -22.796 1.148   28.248 1.000 48.310  ? 1304 MET AAA CA   1 
ATOM   674  C C    . MET A 1 43  ? -22.420 0.998   29.738 1.000 45.800  ? 1304 MET AAA C    1 
ATOM   675  O O    . MET A 1 43  ? -21.201 0.845   30.029 1.000 42.780  ? 1304 MET AAA O    1 
ATOM   676  C CB   . MET A 1 43  ? -22.968 2.623   27.867 1.000 51.050  ? 1304 MET AAA CB   1 
ATOM   677  C CG   . MET A 1 43  ? -22.884 2.876   26.360 1.000 49.640  ? 1304 MET AAA CG   1 
ATOM   678  S SD   . MET A 1 43  ? -23.194 4.622   25.946 1.000 49.340  ? 1304 MET AAA SD   1 
ATOM   679  C CE   . MET A 1 43  ? -21.604 5.390   26.241 1.000 45.350  ? 1304 MET AAA CE   1 
ATOM   680  H H    . MET A 1 43  ? -24.851 0.897   27.618 1.000 45.200  ? 1304 MET AAA H    1 
ATOM   681  H HA   . MET A 1 43  ? -22.066 0.770   27.705 1.000 48.310  ? 1304 MET AAA HA   1 
ATOM   682  H HB2  . MET A 1 43  ? -23.837 2.931   28.193 1.000 51.050  ? 1304 MET AAA HB2  1 
ATOM   683  H HB3  . MET A 1 43  ? -22.274 3.145   28.316 1.000 51.050  ? 1304 MET AAA HB3  1 
ATOM   684  H HG2  . MET A 1 43  ? -21.993 2.622   26.039 1.000 49.640  ? 1304 MET AAA HG2  1 
ATOM   685  H HG3  . MET A 1 43  ? -23.544 2.313   25.901 1.000 49.640  ? 1304 MET AAA HG3  1 
ATOM   686  H HE1  . MET A 1 43  ? -21.662 6.329   26.048 1.000 45.350  ? 1304 MET AAA HE1  1 
ATOM   687  H HE2  . MET A 1 43  ? -21.355 5.266   27.160 1.000 45.350  ? 1304 MET AAA HE2  1 
ATOM   688  H HE3  . MET A 1 43  ? -20.941 4.984   25.670 1.000 45.350  ? 1304 MET AAA HE3  1 
ATOM   689  N N    . GLU A 1 44  ? -23.408 1.025   30.636 1.000 40.500  ? 1305 GLU AAA N    1 
ATOM   690  C CA   . GLU A 1 44  ? -23.245 0.853   32.110 1.000 43.330  ? 1305 GLU AAA CA   1 
ATOM   691  C C    . GLU A 1 44  ? -22.686 -0.534  32.517 1.000 41.730  ? 1305 GLU AAA C    1 
ATOM   692  O O    . GLU A 1 44  ? -22.264 -0.698  33.713 1.000 43.440  ? 1305 GLU AAA O    1 
ATOM   693  C CB   . GLU A 1 44  ? -24.602 1.047   32.796 1.000 44.910  ? 1305 GLU AAA CB   1 
ATOM   694  C CG   . GLU A 1 44  ? -25.130 2.475   32.779 1.000 46.500  ? 1305 GLU AAA CG   1 
ATOM   695  C CD   . GLU A 1 44  ? -26.441 2.623   33.528 1.000 49.730  ? 1305 GLU AAA CD   1 
ATOM   696  O OE1  . GLU A 1 44  ? -26.894 1.614   34.134 1.000 50.910  ? 1305 GLU AAA OE1  1 
ATOM   697  O OE2  . GLU A 1 44  ? -27.024 3.727   33.494 1.000 48.510  ? 1305 GLU AAA OE2  1 
ATOM   698  H H    . GLU A 1 44  ? -24.332 1.176   30.257 1.000 40.500  ? 1305 GLU AAA H    1 
ATOM   699  H HA   . GLU A 1 44  ? -22.600 1.524   32.433 1.000 43.330  ? 1305 GLU AAA HA   1 
ATOM   700  H HB2  . GLU A 1 44  ? -25.261 0.473   32.352 1.000 44.910  ? 1305 GLU AAA HB2  1 
ATOM   701  H HB3  . GLU A 1 44  ? -24.523 0.762   33.730 1.000 44.910  ? 1305 GLU AAA HB3  1 
ATOM   702  H HG2  . GLU A 1 44  ? -24.458 3.067   33.178 1.000 46.500  ? 1305 GLU AAA HG2  1 
ATOM   703  H HG3  . GLU A 1 44  ? -25.253 2.757   31.848 1.000 46.500  ? 1305 GLU AAA HG3  1 
ATOM   704  N N    . ARG A 1 45  ? -22.750 -1.529  31.628 1.000 37.970  ? 1306 ARG AAA N    1 
ATOM   705  C CA   . ARG A 1 45  ? -22.346 -2.938  31.887 1.000 37.840  ? 1306 ARG AAA CA   1 
ATOM   706  C C    . ARG A 1 45  ? -21.015 -3.235  31.188 1.000 38.240  ? 1306 ARG AAA C    1 
ATOM   707  O O    . ARG A 1 45  ? -20.653 -4.433  31.082 1.000 38.960  ? 1306 ARG AAA O    1 
ATOM   708  C CB   . ARG A 1 45  ? -23.472 -3.892  31.473 1.000 36.700  ? 1306 ARG AAA CB   1 
ATOM   709  C CG   . ARG A 1 45  ? -24.678 -3.790  32.398 1.000 39.010  ? 1306 ARG AAA CG   1 
ATOM   710  C CD   . ARG A 1 45  ? -25.941 -4.485  31.900 1.000 42.690  ? 1306 ARG AAA CD   1 
ATOM   711  N NE   . ARG A 1 45  ? -26.974 -4.451  32.926 1.000 45.110  ? 1306 ARG AAA NE   1 
ATOM   712  C CZ   . ARG A 1 45  ? -27.711 -3.388  33.226 1.000 47.880  ? 1306 ARG AAA CZ   1 
ATOM   713  N NH1  . ARG A 1 45  ? -27.598 -2.261  32.544 1.000 53.810  ? 1306 ARG AAA NH1  1 
ATOM   714  N NH2  . ARG A 1 45  ? -28.611 -3.467  34.185 1.000 49.690  ? 1306 ARG AAA NH2  1 
ATOM   715  H H    . ARG A 1 45  ? -23.104 -1.278  30.716 1.000 37.970  ? 1306 ARG AAA H    1 
ATOM   716  H HA   . ARG A 1 45  ? -22.223 -3.054  32.857 1.000 37.840  ? 1306 ARG AAA HA   1 
ATOM   717  H HB2  . ARG A 1 45  ? -23.739 -3.679  30.554 1.000 36.700  ? 1306 ARG AAA HB2  1 
ATOM   718  H HB3  . ARG A 1 45  ? -23.123 -4.808  31.481 1.000 36.700  ? 1306 ARG AAA HB3  1 
ATOM   719  H HG2  . ARG A 1 45  ? -24.452 -4.180  33.269 1.000 39.010  ? 1306 ARG AAA HG2  1 
ATOM   720  H HG3  . ARG A 1 45  ? -24.899 -2.845  32.539 1.000 39.010  ? 1306 ARG AAA HG3  1 
ATOM   721  H HD2  . ARG A 1 45  ? -26.256 -4.037  31.086 1.000 42.690  ? 1306 ARG AAA HD2  1 
ATOM   722  H HD3  . ARG A 1 45  ? -25.727 -5.413  31.664 1.000 42.690  ? 1306 ARG AAA HD3  1 
ATOM   723  H HE   . ARG A 1 45  ? -27.123 -5.181  33.379 1.000 45.110  ? 1306 ARG AAA HE   1 
ATOM   724  H HH11 . ARG A 1 45  ? -27.026 -2.208  31.878 1.000 53.810  ? 1306 ARG AAA HH11 1 
ATOM   725  H HH12 . ARG A 1 45  ? -28.095 -1.568  32.758 1.000 53.810  ? 1306 ARG AAA HH12 1 
ATOM   726  H HH21 . ARG A 1 45  ? -28.720 -4.224  34.623 1.000 49.690  ? 1306 ARG AAA HH21 1 
ATOM   727  H HH22 . ARG A 1 45  ? -29.101 -2.763  34.386 1.000 49.690  ? 1306 ARG AAA HH22 1 
ATOM   728  N N    . LEU A 1 46  ? -20.320 -2.181  30.747 1.000 39.170  ? 1307 LEU AAA N    1 
ATOM   729  C CA   . LEU A 1 46  ? -18.996 -2.259  30.079 1.000 40.390  ? 1307 LEU AAA CA   1 
ATOM   730  C C    . LEU A 1 46  ? -18.011 -1.427  30.899 1.000 43.110  ? 1307 LEU AAA C    1 
ATOM   731  O O    . LEU A 1 46  ? -18.429 -0.379  31.428 1.000 39.670  ? 1307 LEU AAA O    1 
ATOM   732  C CB   . LEU A 1 46  ? -19.062 -1.689  28.661 1.000 41.480  ? 1307 LEU AAA CB   1 
ATOM   733  C CG   . LEU A 1 46  ? -20.136 -2.267  27.752 1.000 43.190  ? 1307 LEU AAA CG   1 
ATOM   734  C CD1  . LEU A 1 46  ? -20.407 -1.324  26.586 1.000 44.700  ? 1307 LEU AAA CD1  1 
ATOM   735  C CD2  . LEU A 1 46  ? -19.746 -3.656  27.254 1.000 46.930  ? 1307 LEU AAA CD2  1 
ATOM   736  H H    . LEU A 1 46  ? -20.747 -1.277  30.890 1.000 39.170  ? 1307 LEU AAA H    1 
ATOM   737  H HA   . LEU A 1 46  ? -18.705 -3.200  30.071 1.000 40.390  ? 1307 LEU AAA HA   1 
ATOM   738  H HB2  . LEU A 1 46  ? -19.206 -0.724  28.724 1.000 41.480  ? 1307 LEU AAA HB2  1 
ATOM   739  H HB3  . LEU A 1 46  ? -18.194 -1.830  28.232 1.000 41.480  ? 1307 LEU AAA HB3  1 
ATOM   740  H HG   . LEU A 1 46  ? -20.969 -2.355  28.279 1.000 43.190  ? 1307 LEU AAA HG   1 
ATOM   741  H HD11 . LEU A 1 46  ? -20.708 -0.464  26.927 1.000 44.700  ? 1307 LEU AAA HD11 1 
ATOM   742  H HD12 . LEU A 1 46  ? -21.094 -1.706  26.013 1.000 44.700  ? 1307 LEU AAA HD12 1 
ATOM   743  H HD13 . LEU A 1 46  ? -19.590 -1.200  26.072 1.000 44.700  ? 1307 LEU AAA HD13 1 
ATOM   744  H HD21 . LEU A 1 46  ? -18.913 -3.600  26.755 1.000 46.930  ? 1307 LEU AAA HD21 1 
ATOM   745  H HD22 . LEU A 1 46  ? -20.448 -4.003  26.677 1.000 46.930  ? 1307 LEU AAA HD22 1 
ATOM   746  H HD23 . LEU A 1 46  ? -19.628 -4.252  28.014 1.000 46.930  ? 1307 LEU AAA HD23 1 
ATOM   747  N N    . ARG A 1 47  ? -16.746 -1.847  30.934 1.000 39.490  ? 1308 ARG AAA N    1 
ATOM   748  C CA   . ARG A 1 47  ? -15.642 -1.047  31.485 1.000 41.700  ? 1308 ARG AAA CA   1 
ATOM   749  C C    . ARG A 1 47  ? -15.128 -0.067  30.440 1.000 42.130  ? 1308 ARG AAA C    1 
ATOM   750  O O    . ARG A 1 47  ? -14.262 -0.444  29.662 1.000 43.280  ? 1308 ARG AAA O    1 
ATOM   751  C CB   . ARG A 1 47  ? -14.508 -1.984  31.876 1.000 51.430  ? 1308 ARG AAA CB   1 
ATOM   752  C CG   . ARG A 1 47  ? -13.394 -1.284  32.637 1.000 53.080  ? 1308 ARG AAA CG   1 
ATOM   753  C CD   . ARG A 1 47  ? -12.358 -2.307  33.028 1.000 55.890  ? 1308 ARG AAA CD   1 
ATOM   754  N NE   . ARG A 1 47  ? -11.473 -1.760  34.027 1.000 62.520  ? 1308 ARG AAA NE   1 
ATOM   755  C CZ   . ARG A 1 47  ? -10.495 -2.441  34.619 1.000 66.150  ? 1308 ARG AAA CZ   1 
ATOM   756  N NH1  . ARG A 1 47  ? -10.229 -3.700  34.306 1.000 60.820  ? 1308 ARG AAA NH1  1 
ATOM   757  N NH2  . ARG A 1 47  ? -9.756  -1.833  35.520 1.000 61.690  ? 1308 ARG AAA NH2  1 
ATOM   758  H H    . ARG A 1 47  ? -16.550 -2.764  30.559 1.000 39.490  ? 1308 ARG AAA H    1 
ATOM   759  H HA   . ARG A 1 47  ? -15.982 -0.531  32.252 1.000 41.700  ? 1308 ARG AAA HA   1 
ATOM   760  H HB2  . ARG A 1 47  ? -14.876 -2.705  32.429 1.000 51.430  ? 1308 ARG AAA HB2  1 
ATOM   761  H HB3  . ARG A 1 47  ? -14.141 -2.387  31.061 1.000 51.430  ? 1308 ARG AAA HB3  1 
ATOM   762  H HG2  . ARG A 1 47  ? -13.000 -0.589  32.068 1.000 53.080  ? 1308 ARG AAA HG2  1 
ATOM   763  H HG3  . ARG A 1 47  ? -13.769 -0.847  33.431 1.000 53.080  ? 1308 ARG AAA HG3  1 
ATOM   764  H HD2  . ARG A 1 47  ? -12.809 -3.107  33.373 1.000 55.890  ? 1308 ARG AAA HD2  1 
ATOM   765  H HD3  . ARG A 1 47  ? -11.851 -2.573  32.232 1.000 55.890  ? 1308 ARG AAA HD3  1 
ATOM   766  H HE   . ARG A 1 47  ? -11.586 -0.927  34.259 1.000 62.520  ? 1308 ARG AAA HE   1 
ATOM   767  H HH11 . ARG A 1 47  ? -10.706 -4.108  33.691 1.000 60.820  ? 1308 ARG AAA HH11 1 
ATOM   768  H HH12 . ARG A 1 47  ? -9.576  -4.124  34.715 1.000 60.820  ? 1308 ARG AAA HH12 1 
ATOM   769  H HH21 . ARG A 1 47  ? -9.914  -0.990  35.721 1.000 61.690  ? 1308 ARG AAA HH21 1 
ATOM   770  H HH22 . ARG A 1 47  ? -9.105  -2.270  35.921 1.000 61.690  ? 1308 ARG AAA HH22 1 
ATOM   771  N N    . ILE A 1 48  ? -15.603 1.171   30.440 1.000 46.470  ? 1309 ILE AAA N    1 
ATOM   772  C CA   . ILE A 1 48  ? -15.285 2.120   29.333 1.000 48.440  ? 1309 ILE AAA CA   1 
ATOM   773  C C    . ILE A 1 48  ? -13.929 2.791   29.601 1.000 48.280  ? 1309 ILE AAA C    1 
ATOM   774  O O    . ILE A 1 48  ? -13.823 3.560   30.579 1.000 42.780  ? 1309 ILE AAA O    1 
ATOM   775  C CB   . ILE A 1 48  ? -16.447 3.113   29.124 1.000 50.620  ? 1309 ILE AAA CB   1 
ATOM   776  C CG1  . ILE A 1 48  ? -17.671 2.403   28.533 1.000 46.090  ? 1309 ILE AAA CG1  1 
ATOM   777  C CG2  . ILE A 1 48  ? -16.007 4.298   28.268 1.000 50.700  ? 1309 ILE AAA CG2  1 
ATOM   778  C CD1  . ILE A 1 48  ? -18.905 3.260   28.499 1.000 50.770  ? 1309 ILE AAA CD1  1 
ATOM   779  H H    . ILE A 1 48  ? -16.191 1.481   31.201 1.000 46.470  ? 1309 ILE AAA H    1 
ATOM   780  H HA   . ILE A 1 48  ? -15.214 1.613   28.504 1.000 48.440  ? 1309 ILE AAA HA   1 
ATOM   781  H HB   . ILE A 1 48  ? -16.699 3.466   30.013 1.000 50.620  ? 1309 ILE AAA HB   1 
ATOM   782  H HG12 . ILE A 1 48  ? -17.458 2.116   27.619 1.000 46.090  ? 1309 ILE AAA HG12 1 
ATOM   783  H HG13 . ILE A 1 48  ? -17.856 1.600   29.065 1.000 46.090  ? 1309 ILE AAA HG13 1 
ATOM   784  H HG21 . ILE A 1 48  ? -15.277 4.767   28.708 1.000 50.700  ? 1309 ILE AAA HG21 1 
ATOM   785  H HG22 . ILE A 1 48  ? -16.753 4.912   28.151 1.000 50.700  ? 1309 ILE AAA HG22 1 
ATOM   786  H HG23 . ILE A 1 48  ? -15.710 3.981   27.398 1.000 50.700  ? 1309 ILE AAA HG23 1 
ATOM   787  H HD11 . ILE A 1 48  ? -19.137 3.533   29.404 1.000 50.770  ? 1309 ILE AAA HD11 1 
ATOM   788  H HD12 . ILE A 1 48  ? -19.642 2.754   28.115 1.000 50.770  ? 1309 ILE AAA HD12 1 
ATOM   789  H HD13 . ILE A 1 48  ? -18.738 4.050   27.956 1.000 50.770  ? 1309 ILE AAA HD13 1 
ATOM   790  N N    . SER A 1 49  ? -12.950 2.527   28.725 1.000 48.760  ? 1310 SER AAA N    1 
ATOM   791  C CA   . SER A 1 49  ? -11.575 3.099   28.761 1.000 45.780  ? 1310 SER AAA CA   1 
ATOM   792  C C    . SER A 1 49  ? -10.781 2.762   27.479 1.000 46.470  ? 1310 SER AAA C    1 
ATOM   793  O O    . SER A 1 49  ? -10.998 1.695   26.872 1.000 51.150  ? 1310 SER AAA O    1 
ATOM   794  C CB   . SER A 1 49  ? -10.861 2.611   30.000 1.000 47.300  ? 1310 SER AAA CB   1 
ATOM   795  O OG   . SER A 1 49  ? -9.512  2.296   29.709 1.000 45.990  ? 1310 SER AAA OG   1 
ATOM   796  H H    . SER A 1 49  ? -13.196 1.881   27.988 1.000 48.760  ? 1310 SER AAA H    1 
ATOM   797  H HA   . SER A 1 49  ? -11.654 4.090   28.809 1.000 45.780  ? 1310 SER AAA HA   1 
ATOM   798  H HB2  . SER A 1 49  ? -10.893 3.311   30.691 1.000 47.300  ? 1310 SER AAA HB2  1 
ATOM   799  H HB3  . SER A 1 49  ? -11.318 1.810   30.345 1.000 47.300  ? 1310 SER AAA HB3  1 
ATOM   800  H HG   . SER A 1 49  ? -9.140  2.027   30.419 0.000 45.990  ? 1310 SER AAA HG   1 
ATOM   801  N N    . GLN A 1 50  ? -9.837  3.614   27.082 1.000 46.740  ? 1311 GLN AAA N    1 
ATOM   802  C CA   . GLN A 1 50  ? -8.983  3.377   25.883 1.000 51.150  ? 1311 GLN AAA CA   1 
ATOM   803  C C    . GLN A 1 50  ? -8.257  2.042   26.009 1.000 46.850  ? 1311 GLN AAA C    1 
ATOM   804  O O    . GLN A 1 50  ? -7.936  1.471   24.976 1.000 55.680  ? 1311 GLN AAA O    1 
ATOM   805  C CB   . GLN A 1 50  ? -8.005  4.536   25.669 1.000 53.780  ? 1311 GLN AAA CB   1 
ATOM   806  C CG   . GLN A 1 50  ? -8.705  5.888   25.464 1.000 55.610  ? 1311 GLN AAA CG   1 
ATOM   807  C CD   . GLN A 1 50  ? -9.486  5.995   24.166 1.000 56.370  ? 1311 GLN AAA CD   1 
ATOM   808  O OE1  . GLN A 1 50  ? -9.090  5.476   23.114 1.000 47.170  ? 1311 GLN AAA OE1  1 
ATOM   809  N NE2  . GLN A 1 50  ? -10.609 6.695   24.232 1.000 50.310  ? 1311 GLN AAA NE2  1 
ATOM   810  H H    . GLN A 1 50  ? -9.702  4.455   27.624 1.000 46.740  ? 1311 GLN AAA H    1 
ATOM   811  H HA   . GLN A 1 50  ? -9.564  3.341   25.088 1.000 51.150  ? 1311 GLN AAA HA   1 
ATOM   812  H HB2  . GLN A 1 50  ? -7.413  4.592   26.448 1.000 53.780  ? 1311 GLN AAA HB2  1 
ATOM   813  H HB3  . GLN A 1 50  ? -7.451  4.336   24.886 1.000 53.780  ? 1311 GLN AAA HB3  1 
ATOM   814  H HG2  . GLN A 1 50  ? -9.327  6.045   26.206 1.000 55.610  ? 1311 GLN AAA HG2  1 
ATOM   815  H HG3  . GLN A 1 50  ? -8.034  6.604   25.475 1.000 55.610  ? 1311 GLN AAA HG3  1 
ATOM   816  H HE21 . GLN A 1 50  ? -11.111 6.796   23.511 0.000 50.310  ? 1311 GLN AAA HE21 1 
ATOM   817  H HE22 . GLN A 1 50  ? -10.857 7.062   24.997 0.000 50.310  ? 1311 GLN AAA HE22 1 
ATOM   818  N N    . LYS A 1 51  ? -8.081  1.547   27.232 1.000 53.220  ? 1312 LYS AAA N    1 
ATOM   819  C CA   . LYS A 1 51  ? -7.392  0.269   27.571 1.000 56.030  ? 1312 LYS AAA CA   1 
ATOM   820  C C    . LYS A 1 51  ? -8.352  -0.912  27.538 1.000 45.140  ? 1312 LYS AAA C    1 
ATOM   821  O O    . LYS A 1 51  ? -7.908  -2.045  27.306 1.000 44.150  ? 1312 LYS AAA O    1 
ATOM   822  C CB   . LYS A 1 51  ? -6.833  0.332   28.995 1.000 68.740  ? 1312 LYS AAA CB   1 
ATOM   823  C CG   . LYS A 1 51  ? -5.684  1.310   29.190 1.000 72.280  ? 1312 LYS AAA CG   1 
ATOM   824  C CD   . LYS A 1 51  ? -4.461  0.891   28.403 1.000 80.350  ? 1312 LYS AAA CD   1 
ATOM   825  C CE   . LYS A 1 51  ? -3.415  1.978   28.308 1.000 91.780  ? 1312 LYS AAA CE   1 
ATOM   826  N NZ   . LYS A 1 51  ? -2.066  1.435   28.595 1.000 96.360  ? 1312 LYS AAA NZ   1 
ATOM   827  H H    . LYS A 1 51  ? -8.461  2.114   27.976 1.000 53.220  ? 1312 LYS AAA H    1 
ATOM   828  H HA   . LYS A 1 51  ? -6.691  0.104   26.899 1.000 56.030  ? 1312 LYS AAA HA   1 
ATOM   829  H HB2  . LYS A 1 51  ? -7.561  0.573   29.605 1.000 68.740  ? 1312 LYS AAA HB2  1 
ATOM   830  H HB3  . LYS A 1 51  ? -6.533  -0.565  29.252 1.000 68.740  ? 1312 LYS AAA HB3  1 
ATOM   831  H HG2  . LYS A 1 51  ? -5.977  2.200   28.898 1.000 72.280  ? 1312 LYS AAA HG2  1 
ATOM   832  H HG3  . LYS A 1 51  ? -5.466  1.350   30.146 1.000 72.280  ? 1312 LYS AAA HG3  1 
ATOM   833  H HD2  . LYS A 1 51  ? -4.061  0.103   28.828 1.000 80.350  ? 1312 LYS AAA HD2  1 
ATOM   834  H HD3  . LYS A 1 51  ? -4.736  0.635   27.497 1.000 80.350  ? 1312 LYS AAA HD3  1 
ATOM   835  H HE2  . LYS A 1 51  ? -3.426  2.365   27.412 1.000 91.780  ? 1312 LYS AAA HE2  1 
ATOM   836  H HE3  . LYS A 1 51  ? -3.623  2.688   28.945 1.000 91.780  ? 1312 LYS AAA HE3  1 
ATOM   837  H HZ1  . LYS A 1 51  ? -2.048  1.084   29.431 1.000 96.360  ? 1312 LYS AAA HZ1  1 
ATOM   838  H HZ2  . LYS A 1 51  ? -1.449  2.097   28.532 1.000 96.360  ? 1312 LYS AAA HZ2  1 
ATOM   839  H HZ3  . LYS A 1 51  ? -1.864  0.784   27.997 1.000 96.360  ? 1312 LYS AAA HZ3  1 
ATOM   840  N N    . TRP A 1 52  ? -9.622  -0.671  27.808 1.000 43.650  ? 1313 TRP AAA N    1 
ATOM   841  C CA   . TRP A 1 52  ? -10.622 -1.766  27.878 1.000 50.140  ? 1313 TRP AAA CA   1 
ATOM   842  C C    . TRP A 1 52  ? -11.659 -1.603  26.753 1.000 45.260  ? 1313 TRP AAA C    1 
ATOM   843  O O    . TRP A 1 52  ? -11.319 -1.952  25.633 1.000 45.960  ? 1313 TRP AAA O    1 
ATOM   844  C CB   . TRP A 1 52  ? -11.187 -1.872  29.308 1.000 49.290  ? 1313 TRP AAA CB   1 
ATOM   845  C CG   . TRP A 1 52  ? -10.101 -2.208  30.291 1.000 49.960  ? 1313 TRP AAA CG   1 
ATOM   846  C CD1  . TRP A 1 52  ? -9.468  -1.320  31.118 1.000 49.720  ? 1313 TRP AAA CD1  1 
ATOM   847  C CD2  . TRP A 1 52  ? -9.429  -3.480  30.462 1.000 44.120  ? 1313 TRP AAA CD2  1 
ATOM   848  N NE1  . TRP A 1 52  ? -8.476  -1.957  31.804 1.000 48.700  ? 1313 TRP AAA NE1  1 
ATOM   849  C CE2  . TRP A 1 52  ? -8.435  -3.282  31.445 1.000 47.330  ? 1313 TRP AAA CE2  1 
ATOM   850  C CE3  . TRP A 1 52  ? -9.579  -4.770  29.915 1.000 46.900  ? 1313 TRP AAA CE3  1 
ATOM   851  C CZ2  . TRP A 1 52  ? -7.610  -4.322  31.894 1.000 43.450  ? 1313 TRP AAA CZ2  1 
ATOM   852  C CZ3  . TRP A 1 52  ? -8.746  -5.791  30.330 1.000 44.240  ? 1313 TRP AAA CZ3  1 
ATOM   853  C CH2  . TRP A 1 52  ? -7.758  -5.559  31.297 1.000 44.850  ? 1313 TRP AAA CH2  1 
ATOM   854  H H    . TRP A 1 52  ? -9.921  0.280   27.971 1.000 43.650  ? 1313 TRP AAA H    1 
ATOM   855  H HA   . TRP A 1 52  ? -10.148 -2.621  27.751 1.000 50.140  ? 1313 TRP AAA HA   1 
ATOM   856  H HB2  . TRP A 1 52  ? -11.604 -1.017  29.537 1.000 49.290  ? 1313 TRP AAA HB2  1 
ATOM   857  H HB3  . TRP A 1 52  ? -11.880 -2.563  29.314 1.000 49.290  ? 1313 TRP AAA HB3  1 
ATOM   858  H HD1  . TRP A 1 52  ? -9.647  -0.393  31.160 1.000 49.720  ? 1313 TRP AAA HD1  1 
ATOM   859  H HE1  . TRP A 1 52  ? -7.942  -1.581  32.389 1.000 48.700  ? 1313 TRP AAA HE1  1 
ATOM   860  H HE3  . TRP A 1 52  ? -10.234 -4.938  29.256 1.000 46.900  ? 1313 TRP AAA HE3  1 
ATOM   861  H HZ2  . TRP A 1 52  ? -6.979  -4.178  32.578 1.000 43.450  ? 1313 TRP AAA HZ2  1 
ATOM   862  H HZ3  . TRP A 1 52  ? -8.850  -6.654  29.961 1.000 44.240  ? 1313 TRP AAA HZ3  1 
ATOM   863  H HH2  . TRP A 1 52  ? -7.202  -6.269  31.565 1.000 44.850  ? 1313 TRP AAA HH2  1 
ATOM   864  N N    . VAL A 1 53  ? -12.894 -1.217  27.050 1.000 43.740  ? 1314 VAL AAA N    1 
ATOM   865  C CA   . VAL A 1 53  ? -13.962 -1.125  26.025 1.000 45.100  ? 1314 VAL AAA CA   1 
ATOM   866  C C    . VAL A 1 53  ? -14.004 0.322   25.541 1.000 43.290  ? 1314 VAL AAA C    1 
ATOM   867  O O    . VAL A 1 53  ? -14.236 1.226   26.379 1.000 36.140  ? 1314 VAL AAA O    1 
ATOM   868  C CB   . VAL A 1 53  ? -15.333 -1.602  26.545 1.000 50.710  ? 1314 VAL AAA CB   1 
ATOM   869  C CG1  . VAL A 1 53  ? -16.410 -1.399  25.492 1.000 53.090  ? 1314 VAL AAA CG1  1 
ATOM   870  C CG2  . VAL A 1 53  ? -15.306 -3.065  26.976 1.000 47.270  ? 1314 VAL AAA CG2  1 
ATOM   871  H H    . VAL A 1 53  ? -13.109 -0.979  28.008 1.000 43.740  ? 1314 VAL AAA H    1 
ATOM   872  H HA   . VAL A 1 53  ? -13.724 -1.705  25.280 1.000 45.100  ? 1314 VAL AAA HA   1 
ATOM   873  H HB   . VAL A 1 53  ? -15.548 -1.061  27.345 1.000 50.710  ? 1314 VAL AAA HB   1 
ATOM   874  H HG11 . VAL A 1 53  ? -16.471 -0.454  25.268 1.000 53.090  ? 1314 VAL AAA HG11 1 
ATOM   875  H HG12 . VAL A 1 53  ? -17.266 -1.706  25.839 1.000 53.090  ? 1314 VAL AAA HG12 1 
ATOM   876  H HG13 . VAL A 1 53  ? -16.184 -1.907  24.694 1.000 53.090  ? 1314 VAL AAA HG13 1 
ATOM   877  H HG21 . VAL A 1 53  ? -15.059 -3.623  26.218 1.000 47.270  ? 1314 VAL AAA HG21 1 
ATOM   878  H HG22 . VAL A 1 53  ? -16.187 -3.326  27.297 1.000 47.270  ? 1314 VAL AAA HG22 1 
ATOM   879  H HG23 . VAL A 1 53  ? -14.655 -3.182  27.689 1.000 47.270  ? 1314 VAL AAA HG23 1 
ATOM   880  N N    . ARG A 1 54  ? -13.803 0.515   24.228 1.000 45.360  ? 1315 ARG AAA N    1 
ATOM   881  C CA   . ARG A 1 54  ? -14.098 1.796   23.526 1.000 45.570  ? 1315 ARG AAA CA   1 
ATOM   882  C C    . ARG A 1 54  ? -15.497 1.715   22.901 1.000 43.880  ? 1315 ARG AAA C    1 
ATOM   883  O O    . ARG A 1 54  ? -15.836 0.642   22.335 1.000 42.470  ? 1315 ARG AAA O    1 
ATOM   884  C CB   . ARG A 1 54  ? -12.969 2.106   22.542 1.000 45.850  ? 1315 ARG AAA CB   1 
ATOM   885  C CG   . ARG A 1 54  ? -11.641 2.352   23.236 1.000 45.890  ? 1315 ARG AAA CG   1 
ATOM   886  C CD   . ARG A 1 54  ? -10.655 3.044   22.350 1.000 49.380  ? 1315 ARG AAA CD   1 
ATOM   887  N NE   . ARG A 1 54  ? -10.341 2.295   21.138 1.000 57.700  ? 1315 ARG AAA NE   1 
ATOM   888  C CZ   . ARG A 1 54  ? -9.797  2.828   20.024 1.000 54.140  ? 1315 ARG AAA CZ   1 
ATOM   889  N NH1  . ARG A 1 54  ? -9.529  4.122   19.962 1.000 53.610  ? 1315 ARG AAA NH1  1 
ATOM   890  N NH2  . ARG A 1 54  ? -9.539  2.070   18.969 1.000 48.940  ? 1315 ARG AAA NH2  1 
ATOM   891  H H    . ARG A 1 54  ? -13.430 -0.261  23.700 1.000 45.360  ? 1315 ARG AAA H    1 
ATOM   892  H HA   . ARG A 1 54  ? -14.086 2.525   24.188 1.000 45.570  ? 1315 ARG AAA HA   1 
ATOM   893  H HB2  . ARG A 1 54  ? -12.880 1.352   21.922 1.000 45.850  ? 1315 ARG AAA HB2  1 
ATOM   894  H HB3  . ARG A 1 54  ? -13.218 2.898   22.021 1.000 45.850  ? 1315 ARG AAA HB3  1 
ATOM   895  H HG2  . ARG A 1 54  ? -11.790 2.900   24.036 1.000 45.890  ? 1315 ARG AAA HG2  1 
ATOM   896  H HG3  . ARG A 1 54  ? -11.263 1.494   23.525 1.000 45.890  ? 1315 ARG AAA HG3  1 
ATOM   897  H HD2  . ARG A 1 54  ? -11.012 3.921   22.094 1.000 49.380  ? 1315 ARG AAA HD2  1 
ATOM   898  H HD3  . ARG A 1 54  ? -9.824  3.196   22.849 1.000 49.380  ? 1315 ARG AAA HD3  1 
ATOM   899  H HE   . ARG A 1 54  ? -10.516 1.441   21.130 1.000 57.700  ? 1315 ARG AAA HE   1 
ATOM   900  H HH11 . ARG A 1 54  ? -9.706  4.639   20.650 1.000 53.610  ? 1315 ARG AAA HH11 1 
ATOM   901  H HH12 . ARG A 1 54  ? -9.175  4.461   19.233 1.000 53.610  ? 1315 ARG AAA HH12 1 
ATOM   902  H HH21 . ARG A 1 54  ? -9.723  1.209   18.992 1.000 48.940  ? 1315 ARG AAA HH21 1 
ATOM   903  H HH22 . ARG A 1 54  ? -9.184  2.429   18.247 1.000 48.940  ? 1315 ARG AAA HH22 1 
ATOM   904  N N    . VAL A 1 55  ? -16.274 2.802   23.015 1.000 42.530  ? 1316 VAL AAA N    1 
ATOM   905  C CA   . VAL A 1 55  ? -17.635 2.928   22.410 1.000 46.240  ? 1316 VAL AAA CA   1 
ATOM   906  C C    . VAL A 1 55  ? -17.718 4.089   21.399 1.000 49.690  ? 1316 VAL AAA C    1 
ATOM   907  O O    . VAL A 1 55  ? -17.055 5.165   21.588 1.000 39.160  ? 1316 VAL AAA O    1 
ATOM   908  C CB   . VAL A 1 55  ? -18.701 3.069   23.503 1.000 44.680  ? 1316 VAL AAA CB   1 
ATOM   909  C CG1  . VAL A 1 55  ? -18.704 1.849   24.422 1.000 44.900  ? 1316 VAL AAA CG1  1 
ATOM   910  C CG2  . VAL A 1 55  ? -18.516 4.337   24.300 1.000 44.690  ? 1316 VAL AAA CG2  1 
ATOM   911  H H    . VAL A 1 55  ? -15.898 3.574   23.547 1.000 42.530  ? 1316 VAL AAA H    1 
ATOM   912  H HA   . VAL A 1 55  ? -17.830 2.110   21.919 1.000 46.240  ? 1316 VAL AAA HA   1 
ATOM   913  H HB   . VAL A 1 55  ? -19.579 3.124   23.051 1.000 44.680  ? 1316 VAL AAA HB   1 
ATOM   914  H HG11 . VAL A 1 55  ? -18.894 1.050   23.901 1.000 44.900  ? 1316 VAL AAA HG11 1 
ATOM   915  H HG12 . VAL A 1 55  ? -19.386 1.960   25.107 1.000 44.900  ? 1316 VAL AAA HG12 1 
ATOM   916  H HG13 . VAL A 1 55  ? -17.833 1.759   24.845 1.000 44.900  ? 1316 VAL AAA HG13 1 
ATOM   917  H HG21 . VAL A 1 55  ? -17.640 4.329   24.724 1.000 44.690  ? 1316 VAL AAA HG21 1 
ATOM   918  H HG22 . VAL A 1 55  ? -19.207 4.395   24.983 1.000 44.690  ? 1316 VAL AAA HG22 1 
ATOM   919  H HG23 . VAL A 1 55  ? -18.581 5.106   23.707 1.000 44.690  ? 1316 VAL AAA HG23 1 
ATOM   920  N N    . ALA A 1 56  ? -18.517 3.871   20.347 1.000 45.740  ? 1317 ALA AAA N    1 
ATOM   921  C CA   . ALA A 1 56  ? -18.976 4.915   19.400 1.000 46.730  ? 1317 ALA AAA CA   1 
ATOM   922  C C    . ALA A 1 56  ? -20.513 4.848   19.271 1.000 43.620  ? 1317 ALA AAA C    1 
ATOM   923  O O    . ALA A 1 56  ? -21.059 3.716   19.345 1.000 42.150  ? 1317 ALA AAA O    1 
ATOM   924  C CB   . ALA A 1 56  ? -18.258 4.747   18.084 1.000 42.270  ? 1317 ALA AAA CB   1 
ATOM   925  H H    . ALA A 1 56  ? -18.816 2.916   20.210 1.000 45.740  ? 1317 ALA AAA H    1 
ATOM   926  H HA   . ALA A 1 56  ? -18.728 5.798   19.762 1.000 46.730  ? 1317 ALA AAA HA   1 
ATOM   927  H HB1  . ALA A 1 56  ? -18.556 5.429   17.462 1.000 42.270  ? 1317 ALA AAA HB1  1 
ATOM   928  H HB2  . ALA A 1 56  ? -17.302 4.833   18.223 1.000 42.270  ? 1317 ALA AAA HB2  1 
ATOM   929  H HB3  . ALA A 1 56  ? -18.453 3.868   17.717 1.000 42.270  ? 1317 ALA AAA HB3  1 
ATOM   930  N N    . VAL A 1 57  ? -21.182 6.009   19.148 1.000 41.500  ? 1318 VAL AAA N    1 
ATOM   931  C CA   . VAL A 1 57  ? -22.658 6.143   18.960 1.000 41.000  ? 1318 VAL AAA CA   1 
ATOM   932  C C    . VAL A 1 57  ? -22.910 6.967   17.699 1.000 42.540  ? 1318 VAL AAA C    1 
ATOM   933  O O    . VAL A 1 57  ? -22.501 8.124   17.691 1.000 45.680  ? 1318 VAL AAA O    1 
ATOM   934  C CB   . VAL A 1 57  ? -23.318 6.786   20.187 1.000 42.180  ? 1318 VAL AAA CB   1 
ATOM   935  C CG1  . VAL A 1 57  ? -24.833 6.810   20.054 1.000 43.500  ? 1318 VAL AAA CG1  1 
ATOM   936  C CG2  . VAL A 1 57  ? -22.911 6.039   21.451 1.000 47.000  ? 1318 VAL AAA CG2  1 
ATOM   937  H H    . VAL A 1 57  ? -20.613 6.843   19.190 1.000 41.500  ? 1318 VAL AAA H    1 
ATOM   938  H HA   . VAL A 1 57  ? -23.034 5.253   18.832 1.000 41.000  ? 1318 VAL AAA HA   1 
ATOM   939  H HB   . VAL A 1 57  ? -22.980 7.713   20.250 1.000 42.180  ? 1318 VAL AAA HB   1 
ATOM   940  H HG11 . VAL A 1 57  ? -25.082 7.323   19.265 1.000 43.500  ? 1318 VAL AAA HG11 1 
ATOM   941  H HG12 . VAL A 1 57  ? -25.222 7.222   20.845 1.000 43.500  ? 1318 VAL AAA HG12 1 
ATOM   942  H HG13 . VAL A 1 57  ? -25.166 5.900   19.966 1.000 43.500  ? 1318 VAL AAA HG13 1 
ATOM   943  H HG21 . VAL A 1 57  ? -23.195 5.111   21.385 1.000 47.000  ? 1318 VAL AAA HG21 1 
ATOM   944  H HG22 . VAL A 1 57  ? -23.333 6.453   22.223 1.000 47.000  ? 1318 VAL AAA HG22 1 
ATOM   945  H HG23 . VAL A 1 57  ? -21.944 6.075   21.553 1.000 47.000  ? 1318 VAL AAA HG23 1 
ATOM   946  N N    . VAL A 1 58  ? -23.534 6.375   16.679 1.000 41.030  ? 1319 VAL AAA N    1 
ATOM   947  C CA   . VAL A 1 58  ? -23.969 7.070   15.436 1.000 41.140  ? 1319 VAL AAA CA   1 
ATOM   948  C C    . VAL A 1 58  ? -25.483 6.907   15.261 1.000 42.840  ? 1319 VAL AAA C    1 
ATOM   949  O O    . VAL A 1 58  ? -25.940 5.761   15.355 1.000 49.440  ? 1319 VAL AAA O    1 
ATOM   950  C CB   . VAL A 1 58  ? -23.214 6.508   14.225 1.000 43.280  ? 1319 VAL AAA CB   1 
ATOM   951  C CG1  . VAL A 1 58  ? -23.589 7.263   12.952 1.000 44.080  ? 1319 VAL AAA CG1  1 
ATOM   952  C CG2  . VAL A 1 58  ? -21.715 6.541   14.447 1.000 43.170  ? 1319 VAL AAA CG2  1 
ATOM   953  H H    . VAL A 1 58  ? -23.713 5.386   16.779 1.000 41.030  ? 1319 VAL AAA H    1 
ATOM   954  H HA   . VAL A 1 58  ? -23.774 8.020   15.531 1.000 41.140  ? 1319 VAL AAA HA   1 
ATOM   955  H HB   . VAL A 1 58  ? -23.484 5.562   14.124 1.000 43.280  ? 1319 VAL AAA HB   1 
ATOM   956  H HG11 . VAL A 1 58  ? -24.545 7.177   12.793 1.000 44.080  ? 1319 VAL AAA HG11 1 
ATOM   957  H HG12 . VAL A 1 58  ? -23.099 6.891   12.198 1.000 44.080  ? 1319 VAL AAA HG12 1 
ATOM   958  H HG13 . VAL A 1 58  ? -23.362 8.204   13.053 1.000 44.080  ? 1319 VAL AAA HG13 1 
ATOM   959  H HG21 . VAL A 1 58  ? -21.428 7.459   14.592 1.000 43.170  ? 1319 VAL AAA HG21 1 
ATOM   960  H HG22 . VAL A 1 58  ? -21.263 6.179   13.665 1.000 43.170  ? 1319 VAL AAA HG22 1 
ATOM   961  H HG23 . VAL A 1 58  ? -21.490 6.005   15.227 1.000 43.170  ? 1319 VAL AAA HG23 1 
ATOM   962  N N    . GLU A 1 59  ? -26.230 7.986   14.984 1.000 43.650  ? 1320 GLU AAA N    1 
ATOM   963  C CA   . GLU A 1 59  ? -27.637 7.911   14.471 1.000 43.770  ? 1320 GLU AAA CA   1 
ATOM   964  C C    . GLU A 1 59  ? -27.613 8.050   12.929 1.000 44.960  ? 1320 GLU AAA C    1 
ATOM   965  O O    . GLU A 1 59  ? -26.925 8.965   12.412 1.000 42.910  ? 1320 GLU AAA O    1 
ATOM   966  C CB   . GLU A 1 59  ? -28.526 8.924   15.199 1.000 41.400  ? 1320 GLU AAA CB   1 
ATOM   967  C CG   . GLU A 1 59  ? -29.922 9.106   14.599 1.000 45.720  ? 1320 GLU AAA CG   1 
ATOM   968  C CD   . GLU A 1 59  ? -29.981 10.010  13.363 1.000 47.920  ? 1320 GLU AAA CD   1 
ATOM   969  O OE1  . GLU A 1 59  ? -29.718 11.239  13.492 1.000 48.460  ? 1320 GLU AAA OE1  1 
ATOM   970  O OE2  . GLU A 1 59  ? -30.259 9.481   12.258 1.000 46.870  ? 1320 GLU AAA OE2  1 
ATOM   971  H H    . GLU A 1 59  ? -25.808 8.891   15.134 1.000 43.650  ? 1320 GLU AAA H    1 
ATOM   972  H HA   . GLU A 1 59  ? -28.010 7.031   14.709 1.000 43.770  ? 1320 GLU AAA HA   1 
ATOM   973  H HB2  . GLU A 1 59  ? -28.630 8.635   16.130 1.000 41.400  ? 1320 GLU AAA HB2  1 
ATOM   974  H HB3  . GLU A 1 59  ? -28.076 9.795   15.193 1.000 41.400  ? 1320 GLU AAA HB3  1 
ATOM   975  H HG2  . GLU A 1 59  ? -30.280 8.226   14.353 1.000 45.720  ? 1320 GLU AAA HG2  1 
ATOM   976  H HG3  . GLU A 1 59  ? -30.516 9.482   15.283 1.000 45.720  ? 1320 GLU AAA HG3  1 
ATOM   977  N N    . TYR A 1 60  ? -28.296 7.152   12.206 1.000 43.450  ? 1321 TYR AAA N    1 
ATOM   978  C CA   . TYR A 1 60  ? -28.317 7.129   10.718 1.000 48.500  ? 1321 TYR AAA CA   1 
ATOM   979  C C    . TYR A 1 60  ? -29.745 7.336   10.181 1.000 50.920  ? 1321 TYR AAA C    1 
ATOM   980  O O    . TYR A 1 60  ? -30.671 6.645   10.626 1.000 47.250  ? 1321 TYR AAA O    1 
ATOM   981  C CB   . TYR A 1 60  ? -27.622 5.871   10.187 1.000 49.390  ? 1321 TYR AAA CB   1 
ATOM   982  C CG   . TYR A 1 60  ? -28.293 4.545   10.451 1.000 50.900  ? 1321 TYR AAA CG   1 
ATOM   983  C CD1  . TYR A 1 60  ? -28.129 3.853   11.645 1.000 46.830  ? 1321 TYR AAA CD1  1 
ATOM   984  C CD2  . TYR A 1 60  ? -29.059 3.945   9.469  1.000 47.210  ? 1321 TYR AAA CD2  1 
ATOM   985  C CE1  . TYR A 1 60  ? -28.698 2.599   11.838 1.000 45.860  ? 1321 TYR AAA CE1  1 
ATOM   986  C CE2  . TYR A 1 60  ? -29.636 2.699   9.655  1.000 46.930  ? 1321 TYR AAA CE2  1 
ATOM   987  C CZ   . TYR A 1 60  ? -29.466 2.020   10.844 1.000 44.260  ? 1321 TYR AAA CZ   1 
ATOM   988  O OH   . TYR A 1 60  ? -30.054 0.796   10.978 1.000 41.330  ? 1321 TYR AAA OH   1 
ATOM   989  H H    . TYR A 1 60  ? -28.822 6.457   12.717 1.000 43.450  ? 1321 TYR AAA H    1 
ATOM   990  H HA   . TYR A 1 60  ? -27.758 7.876   10.382 1.000 48.500  ? 1321 TYR AAA HA   1 
ATOM   991  H HB2  . TYR A 1 60  ? -27.518 5.961   9.217  1.000 49.390  ? 1321 TYR AAA HB2  1 
ATOM   992  H HB3  . TYR A 1 60  ? -26.722 5.828   10.573 1.000 49.390  ? 1321 TYR AAA HB3  1 
ATOM   993  H HD1  . TYR A 1 60  ? -27.580 4.219   12.319 1.000 46.830  ? 1321 TYR AAA HD1  1 
ATOM   994  H HD2  . TYR A 1 60  ? -29.192 4.396   8.652  1.000 47.210  ? 1321 TYR AAA HD2  1 
ATOM   995  H HE1  . TYR A 1 60  ? -28.576 2.144   12.655 1.000 45.860  ? 1321 TYR AAA HE1  1 
ATOM   996  H HE2  . TYR A 1 60  ? -30.156 2.320   8.966  1.000 46.930  ? 1321 TYR AAA HE2  1 
ATOM   997  H HH   . TYR A 1 60  ? -30.597 0.802   11.642 0.000 41.330  ? 1321 TYR AAA HH   1 
ATOM   998  N N    . HIS A 1 61  ? -29.883 8.310   9.262  1.000 54.270  ? 1322 HIS AAA N    1 
ATOM   999  C CA   . HIS A 1 61  ? -31.022 8.532   8.319  1.000 52.250  ? 1322 HIS AAA CA   1 
ATOM   1000 C C    . HIS A 1 61  ? -30.510 8.328   6.870  1.000 49.980  ? 1322 HIS AAA C    1 
ATOM   1001 O O    . HIS A 1 61  ? -29.916 7.264   6.583  1.000 48.870  ? 1322 HIS AAA O    1 
ATOM   1002 C CB   . HIS A 1 61  ? -31.659 9.895   8.640  1.000 48.820  ? 1322 HIS AAA CB   1 
ATOM   1003 C CG   . HIS A 1 61  ? -30.663 10.974  8.877  1.000 52.470  ? 1322 HIS AAA CG   1 
ATOM   1004 N ND1  . HIS A 1 61  ? -30.139 11.234  10.122 1.000 51.220  ? 1322 HIS AAA ND1  1 
ATOM   1005 C CD2  . HIS A 1 61  ? -30.071 11.848  8.033  1.000 54.310  ? 1322 HIS AAA CD2  1 
ATOM   1006 C CE1  . HIS A 1 61  ? -29.257 12.211  10.046 1.000 48.990  ? 1322 HIS AAA CE1  1 
ATOM   1007 N NE2  . HIS A 1 61  ? -29.208 12.611  8.777  1.000 52.530  ? 1322 HIS AAA NE2  1 
ATOM   1008 H H    . HIS A 1 61  ? -29.097 8.944   9.243  1.000 54.270  ? 1322 HIS AAA H    1 
ATOM   1009 H HA   . HIS A 1 61  ? -31.713 7.855   8.510  1.000 52.250  ? 1322 HIS AAA HA   1 
ATOM   1010 H HB2  . HIS A 1 61  ? -32.239 10.157  7.891  1.000 48.820  ? 1322 HIS AAA HB2  1 
ATOM   1011 H HB3  . HIS A 1 61  ? -32.222 9.800   9.440  1.000 48.820  ? 1322 HIS AAA HB3  1 
ATOM   1012 H HD1  . HIS A 1 61  ? -30.340 10.802  10.857 0.000 51.220  ? 1322 HIS AAA HD1  1 
ATOM   1013 H HD2  . HIS A 1 61  ? -30.219 11.923  7.109  1.000 54.310  ? 1322 HIS AAA HD2  1 
ATOM   1014 H HE1  . HIS A 1 61  ? -28.766 12.566  10.767 1.000 48.990  ? 1322 HIS AAA HE1  1 
ATOM   1015 H HE2  . HIS A 1 61  ? -28.696 13.251  8.465  0.000 52.530  ? 1322 HIS AAA HE2  1 
ATOM   1016 N N    . ASP A 1 62  ? -30.644 9.301   5.969  1.000 53.480  ? 1323 ASP AAA N    1 
ATOM   1017 C CA   . ASP A 1 62  ? -29.935 9.204   4.661  1.000 54.900  ? 1323 ASP AAA CA   1 
ATOM   1018 C C    . ASP A 1 62  ? -28.455 9.581   4.853  1.000 55.520  ? 1323 ASP AAA C    1 
ATOM   1019 O O    . ASP A 1 62  ? -27.678 9.402   3.924  1.000 54.100  ? 1323 ASP AAA O    1 
ATOM   1020 C CB   . ASP A 1 62  ? -30.610 10.023  3.554  1.000 58.530  ? 1323 ASP AAA CB   1 
ATOM   1021 C CG   . ASP A 1 62  ? -30.656 11.528  3.763  1.000 64.360  ? 1323 ASP AAA CG   1 
ATOM   1022 O OD1  . ASP A 1 62  ? -29.815 12.102  4.530  1.000 58.460  ? 1323 ASP AAA OD1  1 
ATOM   1023 O OD2  . ASP A 1 62  ? -31.539 12.125  3.139  1.000 74.950  ? 1323 ASP AAA OD2  1 
ATOM   1024 H H    . ASP A 1 62  ? -31.221 10.108  6.158  1.000 53.480  ? 1323 ASP AAA H    1 
ATOM   1025 H HA   . ASP A 1 62  ? -29.986 8.271   4.346  1.000 54.900  ? 1323 ASP AAA HA   1 
ATOM   1026 H HB2  . ASP A 1 62  ? -30.123 9.875   2.718  1.000 58.530  ? 1323 ASP AAA HB2  1 
ATOM   1027 H HB3  . ASP A 1 62  ? -31.540 9.727   3.472  1.000 58.530  ? 1323 ASP AAA HB3  1 
ATOM   1028 N N    . GLY A 1 63  ? -28.058 10.092  6.015  1.000 51.970  ? 1324 GLY AAA N    1 
ATOM   1029 C CA   . GLY A 1 63  ? -26.635 10.238  6.364  1.000 51.130  ? 1324 GLY AAA CA   1 
ATOM   1030 C C    . GLY A 1 63  ? -26.380 9.852   7.807  1.000 54.290  ? 1324 GLY AAA C    1 
ATOM   1031 O O    . GLY A 1 63  ? -27.369 9.634   8.565  1.000 48.980  ? 1324 GLY AAA O    1 
ATOM   1032 H H    . GLY A 1 63  ? -28.760 10.389  6.677  1.000 51.970  ? 1324 GLY AAA H    1 
ATOM   1033 H HA2  . GLY A 1 63  ? -26.095 9.664   5.765  1.000 51.130  ? 1324 GLY AAA HA2  1 
ATOM   1034 H HA3  . GLY A 1 63  ? -26.361 11.178  6.218  1.000 51.130  ? 1324 GLY AAA HA3  1 
ATOM   1035 N N    . SER A 1 64  ? -25.106 9.851   8.193  1.000 46.650  ? 1325 SER AAA N    1 
ATOM   1036 C CA   . SER A 1 64  ? -24.620 9.421   9.525  1.000 43.260  ? 1325 SER AAA CA   1 
ATOM   1037 C C    . SER A 1 64  ? -24.338 10.656  10.388 1.000 46.620  ? 1325 SER AAA C    1 
ATOM   1038 O O    . SER A 1 64  ? -23.576 11.549  9.918  1.000 48.020  ? 1325 SER AAA O    1 
ATOM   1039 C CB   . SER A 1 64  ? -23.407 8.534   9.375  1.000 43.520  ? 1325 SER AAA CB   1 
ATOM   1040 O OG   . SER A 1 64  ? -23.677 7.374   8.577  1.000 38.170  ? 1325 SER AAA OG   1 
ATOM   1041 H H    . SER A 1 64  ? -24.439 10.173  7.506  1.000 46.650  ? 1325 SER AAA H    1 
ATOM   1042 H HA   . SER A 1 64  ? -25.341 8.891   9.960  1.000 43.260  ? 1325 SER AAA HA   1 
ATOM   1043 H HB2  . SER A 1 64  ? -22.681 9.045   8.952  1.000 43.520  ? 1325 SER AAA HB2  1 
ATOM   1044 H HB3  . SER A 1 64  ? -23.106 8.241   10.265 1.000 43.520  ? 1325 SER AAA HB3  1 
ATOM   1045 H HG   . SER A 1 64  ? -22.969 6.913   8.524  0.000 38.170  ? 1325 SER AAA HG   1 
ATOM   1046 N N    . HIS A 1 65  ? -24.962 10.722  11.580 1.000 41.480  ? 1326 HIS AAA N    1 
ATOM   1047 C CA   . HIS A 1 65  ? -24.683 11.727  12.642 1.000 41.420  ? 1326 HIS AAA CA   1 
ATOM   1048 C C    . HIS A 1 65  ? -23.945 11.056  13.827 1.000 41.680  ? 1326 HIS AAA C    1 
ATOM   1049 O O    . HIS A 1 65  ? -24.605 10.499  14.728 1.000 40.090  ? 1326 HIS AAA O    1 
ATOM   1050 C CB   . HIS A 1 65  ? -25.984 12.427  13.017 1.000 37.610  ? 1326 HIS AAA CB   1 
ATOM   1051 C CG   . HIS A 1 65  ? -25.819 13.596  13.930 1.000 45.400  ? 1326 HIS AAA CG   1 
ATOM   1052 N ND1  . HIS A 1 65  ? -24.677 13.793  14.708 1.000 48.210  ? 1326 HIS AAA ND1  1 
ATOM   1053 C CD2  . HIS A 1 65  ? -26.667 14.612  14.233 1.000 43.250  ? 1326 HIS AAA CD2  1 
ATOM   1054 C CE1  . HIS A 1 65  ? -24.829 14.888  15.438 1.000 45.320  ? 1326 HIS AAA CE1  1 
ATOM   1055 N NE2  . HIS A 1 65  ? -26.039 15.404  15.154 1.000 46.000  ? 1326 HIS AAA NE2  1 
ATOM   1056 H H    . HIS A 1 65  ? -25.672 10.021  11.739 1.000 41.480  ? 1326 HIS AAA H    1 
ATOM   1057 H HA   . HIS A 1 65  ? -24.089 12.416  12.262 1.000 41.420  ? 1326 HIS AAA HA   1 
ATOM   1058 H HB2  . HIS A 1 65  ? -26.424 12.737  12.195 1.000 37.610  ? 1326 HIS AAA HB2  1 
ATOM   1059 H HB3  . HIS A 1 65  ? -26.579 11.777  13.452 1.000 37.610  ? 1326 HIS AAA HB3  1 
ATOM   1060 H HD1  . HIS A 1 65  ? -23.979 13.264  14.727 0.000 48.210  ? 1326 HIS AAA HD1  1 
ATOM   1061 H HD2  . HIS A 1 65  ? -27.526 14.750  13.879 1.000 43.250  ? 1326 HIS AAA HD2  1 
ATOM   1062 H HE1  . HIS A 1 65  ? -24.199 15.236  16.045 1.000 45.320  ? 1326 HIS AAA HE1  1 
ATOM   1063 H HE2  . HIS A 1 65  ? -26.378 16.131  15.508 0.000 46.000  ? 1326 HIS AAA HE2  1 
ATOM   1064 N N    . ALA A 1 66  ? -22.610 11.114  13.828 1.000 43.280  ? 1327 ALA AAA N    1 
ATOM   1065 C CA   . ALA A 1 66  ? -21.713 10.607  14.909 1.000 47.470  ? 1327 ALA AAA CA   1 
ATOM   1066 C C    . ALA A 1 66  ? -21.842 11.525  16.133 1.000 47.720  ? 1327 ALA AAA C    1 
ATOM   1067 O O    . ALA A 1 66  ? -21.793 12.752  15.964 1.000 52.460  ? 1327 ALA AAA O    1 
ATOM   1068 C CB   . ALA A 1 66  ? -20.281 10.514  14.418 1.000 40.870  ? 1327 ALA AAA CB   1 
ATOM   1069 H H    . ALA A 1 66  ? -22.202 11.545  13.011 1.000 43.280  ? 1327 ALA AAA H    1 
ATOM   1070 H HA   . ALA A 1 66  ? -22.005 9.699   15.159 1.000 47.470  ? 1327 ALA AAA HA   1 
ATOM   1071 H HB1  . ALA A 1 66  ? -19.714 10.184  15.132 1.000 40.870  ? 1327 ALA AAA HB1  1 
ATOM   1072 H HB2  . ALA A 1 66  ? -20.235 9.906   13.663 1.000 40.870  ? 1327 ALA AAA HB2  1 
ATOM   1073 H HB3  . ALA A 1 66  ? -19.974 11.394  14.143 1.000 40.870  ? 1327 ALA AAA HB3  1 
ATOM   1074 N N    . TYR A 1 67  ? -22.093 10.961  17.313 1.000 46.700  ? 1328 TYR AAA N    1 
ATOM   1075 C CA   . TYR A 1 67  ? -22.144 11.709  18.591 1.000 41.110  ? 1328 TYR AAA CA   1 
ATOM   1076 C C    . TYR A 1 67  ? -20.944 11.406  19.494 1.000 41.960  ? 1328 TYR AAA C    1 
ATOM   1077 O O    . TYR A 1 67  ? -20.585 12.277  20.332 1.000 45.290  ? 1328 TYR AAA O    1 
ATOM   1078 C CB   . TYR A 1 67  ? -23.419 11.366  19.335 1.000 40.000  ? 1328 TYR AAA CB   1 
ATOM   1079 C CG   . TYR A 1 67  ? -24.669 12.008  18.810 1.000 40.780  ? 1328 TYR AAA CG   1 
ATOM   1080 C CD1  . TYR A 1 67  ? -25.368 11.469  17.741 1.000 44.420  ? 1328 TYR AAA CD1  1 
ATOM   1081 C CD2  . TYR A 1 67  ? -25.204 13.106  19.457 1.000 38.920  ? 1328 TYR AAA CD2  1 
ATOM   1082 C CE1  . TYR A 1 67  ? -26.568 12.028  17.314 1.000 44.910  ? 1328 TYR AAA CE1  1 
ATOM   1083 C CE2  . TYR A 1 67  ? -26.398 13.673  19.043 1.000 44.400  ? 1328 TYR AAA CE2  1 
ATOM   1084 C CZ   . TYR A 1 67  ? -27.076 13.140  17.964 1.000 43.950  ? 1328 TYR AAA CZ   1 
ATOM   1085 O OH   . TYR A 1 67  ? -28.264 13.695  17.617 1.000 47.570  ? 1328 TYR AAA OH   1 
ATOM   1086 H H    . TYR A 1 67  ? -22.256 9.964   17.319 1.000 46.700  ? 1328 TYR AAA H    1 
ATOM   1087 H HA   . TYR A 1 67  ? -22.119 12.679  18.391 1.000 41.110  ? 1328 TYR AAA HA   1 
ATOM   1088 H HB2  . TYR A 1 67  ? -23.538 10.394  19.314 1.000 40.000  ? 1328 TYR AAA HB2  1 
ATOM   1089 H HB3  . TYR A 1 67  ? -23.309 11.625  20.274 1.000 40.000  ? 1328 TYR AAA HB3  1 
ATOM   1090 H HD1  . TYR A 1 67  ? -25.051 10.680  17.333 1.000 44.420  ? 1328 TYR AAA HD1  1 
ATOM   1091 H HD2  . TYR A 1 67  ? -24.749 13.478  20.195 1.000 38.920  ? 1328 TYR AAA HD2  1 
ATOM   1092 H HE1  . TYR A 1 67  ? -27.033 11.651  16.585 1.000 44.910  ? 1328 TYR AAA HE1  1 
ATOM   1093 H HE2  . TYR A 1 67  ? -26.741 14.430  19.488 1.000 44.400  ? 1328 TYR AAA HE2  1 
ATOM   1094 H HH   . TYR A 1 67  ? -28.895 13.121  17.710 0.000 47.570  ? 1328 TYR AAA HH   1 
ATOM   1095 N N    . ILE A 1 68  ? -20.388 10.199  19.390 1.000 39.470  ? 1329 ILE AAA N    1 
ATOM   1096 C CA   . ILE A 1 68  ? -19.193 9.749   20.150 1.000 40.290  ? 1329 ILE AAA CA   1 
ATOM   1097 C C    . ILE A 1 68  ? -18.287 8.969   19.200 1.000 40.250  ? 1329 ILE AAA C    1 
ATOM   1098 O O    . ILE A 1 68  ? -18.778 7.987   18.604 1.000 40.380  ? 1329 ILE AAA O    1 
ATOM   1099 C CB   . ILE A 1 68  ? -19.589 8.850   21.349 1.000 46.000  ? 1329 ILE AAA CB   1 
ATOM   1100 C CG1  . ILE A 1 68  ? -20.449 9.572   22.387 1.000 42.350  ? 1329 ILE AAA CG1  1 
ATOM   1101 C CG2  . ILE A 1 68  ? -18.334 8.243   21.974 1.000 47.470  ? 1329 ILE AAA CG2  1 
ATOM   1102 C CD1  . ILE A 1 68  ? -21.340 8.669   23.194 1.000 44.960  ? 1329 ILE AAA CD1  1 
ATOM   1103 H H    . ILE A 1 68  ? -20.828 9.562   18.742 1.000 39.470  ? 1329 ILE AAA H    1 
ATOM   1104 H HA   . ILE A 1 68  ? -18.714 10.537  20.464 1.000 40.290  ? 1329 ILE AAA HA   1 
ATOM   1105 H HB   . ILE A 1 68  ? -20.144 8.112   20.995 1.000 46.000  ? 1329 ILE AAA HB   1 
ATOM   1106 H HG12 . ILE A 1 68  ? -19.859 10.057  23.003 1.000 42.350  ? 1329 ILE AAA HG12 1 
ATOM   1107 H HG13 . ILE A 1 68  ? -21.010 10.232  21.926 1.000 42.350  ? 1329 ILE AAA HG13 1 
ATOM   1108 H HG21 . ILE A 1 68  ? -17.866 7.704   21.312 1.000 47.470  ? 1329 ILE AAA HG21 1 
ATOM   1109 H HG22 . ILE A 1 68  ? -18.583 7.677   22.725 1.000 47.470  ? 1329 ILE AAA HG22 1 
ATOM   1110 H HG23 . ILE A 1 68  ? -17.747 8.954   22.286 1.000 47.470  ? 1329 ILE AAA HG23 1 
ATOM   1111 H HD11 . ILE A 1 68  ? -21.950 8.198   22.600 1.000 44.960  ? 1329 ILE AAA HD11 1 
ATOM   1112 H HD12 . ILE A 1 68  ? -21.852 9.199   23.829 1.000 44.960  ? 1329 ILE AAA HD12 1 
ATOM   1113 H HD13 . ILE A 1 68  ? -20.797 8.023   23.678 1.000 44.960  ? 1329 ILE AAA HD13 1 
ATOM   1114 N N    . GLY A 1 69  ? -17.005 9.329   19.121 1.000 39.780  ? 1330 GLY AAA N    1 
ATOM   1115 C CA   . GLY A 1 69  ? -15.981 8.477   18.474 1.000 41.270  ? 1330 GLY AAA CA   1 
ATOM   1116 C C    . GLY A 1 69  ? -15.283 7.569   19.486 1.000 43.650  ? 1330 GLY AAA C    1 
ATOM   1117 O O    . GLY A 1 69  ? -15.274 7.907   20.666 1.000 47.910  ? 1330 GLY AAA O    1 
ATOM   1118 H H    . GLY A 1 69  ? -16.729 10.215  19.518 1.000 39.780  ? 1330 GLY AAA H    1 
ATOM   1119 H HA2  . GLY A 1 69  ? -16.415 7.923   17.777 1.000 41.270  ? 1330 GLY AAA HA2  1 
ATOM   1120 H HA3  . GLY A 1 69  ? -15.310 9.056   18.033 1.000 41.270  ? 1330 GLY AAA HA3  1 
ATOM   1121 N N    . LEU A 1 70  ? -14.736 6.438   19.038 1.000 43.720  ? 1331 LEU AAA N    1 
ATOM   1122 C CA   . LEU A 1 70  ? -13.978 5.463   19.857 1.000 45.330  ? 1331 LEU AAA CA   1 
ATOM   1123 C C    . LEU A 1 70  ? -12.866 6.173   20.667 1.000 54.620  ? 1331 LEU AAA C    1 
ATOM   1124 O O    . LEU A 1 70  ? -12.528 5.710   21.786 1.000 54.040  ? 1331 LEU AAA O    1 
ATOM   1125 C CB   . LEU A 1 70  ? -13.375 4.427   18.903 1.000 42.100  ? 1331 LEU AAA CB   1 
ATOM   1126 C CG   . LEU A 1 70  ? -14.338 3.451   18.248 1.000 39.010  ? 1331 LEU AAA CG   1 
ATOM   1127 C CD1  . LEU A 1 70  ? -13.593 2.554   17.268 1.000 39.300  ? 1331 LEU AAA CD1  1 
ATOM   1128 C CD2  . LEU A 1 70  ? -15.057 2.597   19.292 1.000 41.690  ? 1331 LEU AAA CD2  1 
ATOM   1129 H H    . LEU A 1 70  ? -14.866 6.258   18.053 1.000 43.720  ? 1331 LEU AAA H    1 
ATOM   1130 H HA   . LEU A 1 70  ? -14.599 5.041   20.495 1.000 45.330  ? 1331 LEU AAA HA   1 
ATOM   1131 H HB2  . LEU A 1 70  ? -12.904 4.903   18.190 1.000 42.100  ? 1331 LEU AAA HB2  1 
ATOM   1132 H HB3  . LEU A 1 70  ? -12.712 3.904   19.396 1.000 42.100  ? 1331 LEU AAA HB3  1 
ATOM   1133 H HG   . LEU A 1 70  ? -15.021 3.975   17.761 1.000 39.010  ? 1331 LEU AAA HG   1 
ATOM   1134 H HD11 . LEU A 1 70  ? -13.176 3.101   16.580 1.000 39.300  ? 1331 LEU AAA HD11 1 
ATOM   1135 H HD12 . LEU A 1 70  ? -14.219 1.933   16.856 1.000 39.300  ? 1331 LEU AAA HD12 1 
ATOM   1136 H HD13 . LEU A 1 70  ? -12.907 2.054   17.743 1.000 39.300  ? 1331 LEU AAA HD13 1 
ATOM   1137 H HD21 . LEU A 1 70  ? -14.402 2.091   19.804 1.000 41.690  ? 1331 LEU AAA HD21 1 
ATOM   1138 H HD22 . LEU A 1 70  ? -15.666 1.983   18.846 1.000 41.690  ? 1331 LEU AAA HD22 1 
ATOM   1139 H HD23 . LEU A 1 70  ? -15.561 3.174   19.892 1.000 41.690  ? 1331 LEU AAA HD23 1 
ATOM   1140 N N    . LYS A 1 71  ? -12.290 7.245   20.121 1.000 53.360  ? 1332 LYS AAA N    1 
ATOM   1141 C CA   . LYS A 1 71  ? -11.072 7.899   20.650 1.000 50.470  ? 1332 LYS AAA CA   1 
ATOM   1142 C C    . LYS A 1 71  ? -11.420 9.050   21.578 1.000 51.380  ? 1332 LYS AAA C    1 
ATOM   1143 O O    . LYS A 1 71  ? -10.490 9.507   22.216 1.000 58.040  ? 1332 LYS AAA O    1 
ATOM   1144 C CB   . LYS A 1 71  ? -10.241 8.501   19.523 1.000 54.510  ? 1332 LYS AAA CB   1 
ATOM   1145 C CG   . LYS A 1 71  ? -9.345  7.510   18.815 1.000 59.070  ? 1332 LYS AAA CG   1 
ATOM   1146 C CD   . LYS A 1 71  ? -8.765  8.114   17.587 1.000 69.220  ? 1332 LYS AAA CD   1 
ATOM   1147 C CE   . LYS A 1 71  ? -7.995  7.086   16.798 1.000 85.860  ? 1332 LYS AAA CE   1 
ATOM   1148 N NZ   . LYS A 1 71  ? -7.864  7.482   15.377 1.000 97.590  ? 1332 LYS AAA NZ   1 
ATOM   1149 H H    . LYS A 1 71  ? -12.730 7.620   19.293 1.000 53.360  ? 1332 LYS AAA H    1 
ATOM   1150 H HA   . LYS A 1 71  ? -10.563 7.236   21.171 1.000 50.470  ? 1332 LYS AAA HA   1 
ATOM   1151 H HB2  . LYS A 1 71  ? -10.849 8.909   18.871 1.000 54.510  ? 1332 LYS AAA HB2  1 
ATOM   1152 H HB3  . LYS A 1 71  ? -9.693  9.225   19.892 1.000 54.510  ? 1332 LYS AAA HB3  1 
ATOM   1153 H HG2  . LYS A 1 71  ? -8.630  7.240   19.430 1.000 59.070  ? 1332 LYS AAA HG2  1 
ATOM   1154 H HG3  . LYS A 1 71  ? -9.875  6.718   18.585 1.000 59.070  ? 1332 LYS AAA HG3  1 
ATOM   1155 H HD2  . LYS A 1 71  ? -9.490  8.485   17.040 1.000 69.220  ? 1332 LYS AAA HD2  1 
ATOM   1156 H HD3  . LYS A 1 71  ? -8.174  8.854   17.843 1.000 69.220  ? 1332 LYS AAA HD3  1 
ATOM   1157 H HE2  . LYS A 1 71  ? -7.105  6.977   17.184 1.000 85.860  ? 1332 LYS AAA HE2  1 
ATOM   1158 H HE3  . LYS A 1 71  ? -8.451  6.225   16.850 1.000 85.860  ? 1332 LYS AAA HE3  1 
ATOM   1159 H HZ1  . LYS A 1 71  ? -8.687  7.572   15.006 1.000 97.590  ? 1332 LYS AAA HZ1  1 
ATOM   1160 H HZ2  . LYS A 1 71  ? -7.396  6.851   14.924 1.000 97.590  ? 1332 LYS AAA HZ2  1 
ATOM   1161 H HZ3  . LYS A 1 71  ? -7.426  8.274   15.318 1.000 97.590  ? 1332 LYS AAA HZ3  1 
ATOM   1162 N N    . ASP A 1 72  ? -12.678 9.511   21.624 1.000 53.570  ? 1333 ASP AAA N    1 
ATOM   1163 C CA   . ASP A 1 72  ? -13.137 10.638  22.488 1.000 53.630  ? 1333 ASP AAA CA   1 
ATOM   1164 C C    . ASP A 1 72  ? -12.772 10.332  23.943 1.000 63.120  ? 1333 ASP AAA C    1 
ATOM   1165 O O    . ASP A 1 72  ? -13.500 9.581   24.579 1.000 69.810  ? 1333 ASP AAA O    1 
ATOM   1166 C CB   . ASP A 1 72  ? -14.649 10.888  22.396 1.000 53.230  ? 1333 ASP AAA CB   1 
ATOM   1167 C CG   . ASP A 1 72  ? -15.146 11.265  21.011 1.000 54.360  ? 1333 ASP AAA CG   1 
ATOM   1168 O OD1  . ASP A 1 72  ? -14.304 11.375  20.087 1.000 54.000  ? 1333 ASP AAA OD1  1 
ATOM   1169 O OD2  . ASP A 1 72  ? -16.371 11.433  20.860 1.000 58.070  ? 1333 ASP AAA OD2  1 
ATOM   1170 H H    . ASP A 1 72  ? -13.345 9.048   21.023 1.000 53.570  ? 1333 ASP AAA H    1 
ATOM   1171 H HA   . ASP A 1 72  ? -12.668 11.459  22.207 1.000 53.630  ? 1333 ASP AAA HA   1 
ATOM   1172 H HB2  . ASP A 1 72  ? -15.116 10.068  22.658 1.000 53.230  ? 1333 ASP AAA HB2  1 
ATOM   1173 H HB3  . ASP A 1 72  ? -14.879 11.626  22.997 1.000 53.230  ? 1333 ASP AAA HB3  1 
ATOM   1174 N N    . ARG A 1 73  ? -11.696 10.909  24.468 1.000 74.170  ? 1334 ARG AAA N    1 
ATOM   1175 C CA   . ARG A 1 73  ? -11.228 10.637  25.857 1.000 67.610  ? 1334 ARG AAA CA   1 
ATOM   1176 C C    . ARG A 1 73  ? -12.052 11.476  26.828 1.000 61.820  ? 1334 ARG AAA C    1 
ATOM   1177 O O    . ARG A 1 73  ? -11.604 12.568  27.111 1.000 66.230  ? 1334 ARG AAA O    1 
ATOM   1178 C CB   . ARG A 1 73  ? -9.736  10.948  25.972 1.000 69.110  ? 1334 ARG AAA CB   1 
ATOM   1179 C CG   . ARG A 1 73  ? -8.857  9.882   25.330 1.000 80.720  ? 1334 ARG AAA CG   1 
ATOM   1180 C CD   . ARG A 1 73  ? -7.571  10.423  24.733 1.000 86.510  ? 1334 ARG AAA CD   1 
ATOM   1181 N NE   . ARG A 1 73  ? -6.484  9.449   24.780 1.000 95.080  ? 1334 ARG AAA NE   1 
ATOM   1182 C CZ   . ARG A 1 73  ? -5.737  9.171   25.857 1.000 109.990 ? 1334 ARG AAA CZ   1 
ATOM   1183 N NH1  . ARG A 1 73  ? -5.955  9.787   27.009 1.000 113.490 ? 1334 ARG AAA NH1  1 
ATOM   1184 N NH2  . ARG A 1 73  ? -4.773  8.265   25.782 1.000 110.310 ? 1334 ARG AAA NH2  1 
ATOM   1185 H H    . ARG A 1 73  ? -11.179 11.559  23.893 1.000 74.170  ? 1334 ARG AAA H    1 
ATOM   1186 H HA   . ARG A 1 73  ? -11.373 9.683   26.054 1.000 67.610  ? 1334 ARG AAA HA   1 
ATOM   1187 H HB2  . ARG A 1 73  ? -9.564  11.813  25.544 1.000 69.110  ? 1334 ARG AAA HB2  1 
ATOM   1188 H HB3  . ARG A 1 73  ? -9.507  11.030  26.921 1.000 69.110  ? 1334 ARG AAA HB3  1 
ATOM   1189 H HG2  . ARG A 1 73  ? -8.622  9.208   26.003 1.000 80.720  ? 1334 ARG AAA HG2  1 
ATOM   1190 H HG3  . ARG A 1 73  ? -9.360  9.434   24.617 1.000 80.720  ? 1334 ARG AAA HG3  1 
ATOM   1191 H HD2  . ARG A 1 73  ? -7.732  10.682  23.801 1.000 86.510  ? 1334 ARG AAA HD2  1 
ATOM   1192 H HD3  . ARG A 1 73  ? -7.303  11.230  25.222 1.000 86.510  ? 1334 ARG AAA HD3  1 
ATOM   1193 H HE   . ARG A 1 73  ? -6.300  9.008   24.051 1.000 95.080  ? 1334 ARG AAA HE   1 
ATOM   1194 H HH11 . ARG A 1 73  ? -6.596  10.385  27.071 1.000 113.490 ? 1334 ARG AAA HH11 1 
ATOM   1195 H HH12 . ARG A 1 73  ? -5.458  9.596   27.708 1.000 113.490 ? 1334 ARG AAA HH12 1 
ATOM   1196 H HH21 . ARG A 1 73  ? -4.624  7.845   25.022 1.000 110.310 ? 1334 ARG AAA HH21 1 
ATOM   1197 H HH22 . ARG A 1 73  ? -4.284  8.085   26.492 1.000 110.310 ? 1334 ARG AAA HH22 1 
ATOM   1198 N N    . LYS A 1 74  ? -13.230 10.990  27.244 1.000 60.970  ? 1335 LYS AAA N    1 
ATOM   1199 C CA   . LYS A 1 74  ? -14.145 11.617  28.234 1.000 56.850  ? 1335 LYS AAA CA   1 
ATOM   1200 C C    . LYS A 1 74  ? -14.546 10.589  29.295 1.000 58.040  ? 1335 LYS AAA C    1 
ATOM   1201 O O    . LYS A 1 74  ? -14.403 9.390   29.050 1.000 52.720  ? 1335 LYS AAA O    1 
ATOM   1202 C CB   . LYS A 1 74  ? -15.426 12.120  27.568 1.000 58.130  ? 1335 LYS AAA CB   1 
ATOM   1203 C CG   . LYS A 1 74  ? -15.232 13.112  26.435 1.000 59.890  ? 1335 LYS AAA CG   1 
ATOM   1204 C CD   . LYS A 1 74  ? -16.532 13.500  25.762 1.000 58.730  ? 1335 LYS AAA CD   1 
ATOM   1205 C CE   . LYS A 1 74  ? -16.318 13.928  24.334 1.000 59.590  ? 1335 LYS AAA CE   1 
ATOM   1206 N NZ   . LYS A 1 74  ? -17.412 14.822  23.914 1.000 66.400  ? 1335 LYS AAA NZ   1 
ATOM   1207 H H    . LYS A 1 74  ? -13.489 10.110  26.822 1.000 60.970  ? 1335 LYS AAA H    1 
ATOM   1208 H HA   . LYS A 1 74  ? -13.667 12.355  28.678 1.000 56.850  ? 1335 LYS AAA HA   1 
ATOM   1209 H HB2  . LYS A 1 74  ? -15.922 11.348  27.223 1.000 58.130  ? 1335 LYS AAA HB2  1 
ATOM   1210 H HB3  . LYS A 1 74  ? -15.990 12.537  28.252 1.000 58.130  ? 1335 LYS AAA HB3  1 
ATOM   1211 H HG2  . LYS A 1 74  ? -14.805 13.919  26.795 1.000 59.890  ? 1335 LYS AAA HG2  1 
ATOM   1212 H HG3  . LYS A 1 74  ? -14.634 12.712  25.768 1.000 59.890  ? 1335 LYS AAA HG3  1 
ATOM   1213 H HD2  . LYS A 1 74  ? -17.146 12.735  25.787 1.000 58.730  ? 1335 LYS AAA HD2  1 
ATOM   1214 H HD3  . LYS A 1 74  ? -16.947 14.233  26.265 1.000 58.730  ? 1335 LYS AAA HD3  1 
ATOM   1215 H HE2  . LYS A 1 74  ? -15.461 14.389  24.256 1.000 59.590  ? 1335 LYS AAA HE2  1 
ATOM   1216 H HE3  . LYS A 1 74  ? -16.289 13.141  23.758 1.000 59.590  ? 1335 LYS AAA HE3  1 
ATOM   1217 H HZ1  . LYS A 1 74  ? -18.206 14.389  23.982 1.000 66.400  ? 1335 LYS AAA HZ1  1 
ATOM   1218 H HZ2  . LYS A 1 74  ? -17.283 15.083  23.055 1.000 66.400  ? 1335 LYS AAA HZ2  1 
ATOM   1219 H HZ3  . LYS A 1 74  ? -17.430 15.556  24.446 1.000 66.400  ? 1335 LYS AAA HZ3  1 
ATOM   1220 N N    . ARG A 1 75  ? -15.105 11.078  30.398 1.000 62.050  ? 1336 ARG AAA N    1 
ATOM   1221 C CA   . ARG A 1 75  ? -15.635 10.311  31.556 1.000 67.270  ? 1336 ARG AAA CA   1 
ATOM   1222 C C    . ARG A 1 75  ? -16.836 9.466   31.139 1.000 64.990  ? 1336 ARG AAA C    1 
ATOM   1223 O O    . ARG A 1 75  ? -17.816 10.000  30.613 1.000 66.010  ? 1336 ARG AAA O    1 
ATOM   1224 C CB   . ARG A 1 75  ? -16.074 11.302  32.639 1.000 77.930  ? 1336 ARG AAA CB   1 
ATOM   1225 C CG   . ARG A 1 75  ? -15.888 10.798  34.062 1.000 91.830  ? 1336 ARG AAA CG   1 
ATOM   1226 C CD   . ARG A 1 75  ? -16.391 11.774  35.111 1.000 98.770  ? 1336 ARG AAA CD   1 
ATOM   1227 N NE   . ARG A 1 75  ? -15.779 13.083  34.935 1.000 102.720 ? 1336 ARG AAA NE   1 
ATOM   1228 C CZ   . ARG A 1 75  ? -14.553 13.415  35.329 1.000 109.990 ? 1336 ARG AAA CZ   1 
ATOM   1229 N NH1  . ARG A 1 75  ? -13.779 12.534  35.942 1.000 116.310 ? 1336 ARG AAA NH1  1 
ATOM   1230 N NH2  . ARG A 1 75  ? -14.099 14.636  35.102 1.000 114.870 ? 1336 ARG AAA NH2  1 
ATOM   1231 H H    . ARG A 1 75  ? -15.156 12.087  30.411 1.000 62.050  ? 1336 ARG AAA H    1 
ATOM   1232 H HA   . ARG A 1 75  ? -14.929 9.703   31.877 1.000 67.270  ? 1336 ARG AAA HA   1 
ATOM   1233 H HB2  . ARG A 1 75  ? -15.561 12.130  32.530 1.000 77.930  ? 1336 ARG AAA HB2  1 
ATOM   1234 H HB3  . ARG A 1 75  ? -17.021 11.514  32.502 1.000 77.930  ? 1336 ARG AAA HB3  1 
ATOM   1235 H HG2  . ARG A 1 75  ? -16.367 9.949   34.170 1.000 91.830  ? 1336 ARG AAA HG2  1 
ATOM   1236 H HG3  . ARG A 1 75  ? -14.935 10.629  34.224 1.000 91.830  ? 1336 ARG AAA HG3  1 
ATOM   1237 H HD2  . ARG A 1 75  ? -17.367 11.848  35.041 1.000 98.770  ? 1336 ARG AAA HD2  1 
ATOM   1238 H HD3  . ARG A 1 75  ? -16.183 11.424  36.003 1.000 98.770  ? 1336 ARG AAA HD3  1 
ATOM   1239 H HE   . ARG A 1 75  ? -16.249 13.703  34.541 1.000 102.720 ? 1336 ARG AAA HE   1 
ATOM   1240 H HH11 . ARG A 1 75  ? -14.076 11.720  36.092 1.000 116.310 ? 1336 ARG AAA HH11 1 
ATOM   1241 H HH12 . ARG A 1 75  ? -12.970 12.765  36.198 1.000 116.310 ? 1336 ARG AAA HH12 1 
ATOM   1242 H HH21 . ARG A 1 75  ? -14.610 15.224  34.691 1.000 114.870 ? 1336 ARG AAA HH21 1 
ATOM   1243 H HH22 . ARG A 1 75  ? -13.287 14.857  35.362 1.000 114.870 ? 1336 ARG AAA HH22 1 
ATOM   1244 N N    . PRO A 1 76  ? -16.821 8.135   31.399 1.000 61.060  ? 1337 PRO AAA N    1 
ATOM   1245 C CA   . PRO A 1 76  ? -17.973 7.267   31.123 1.000 57.400  ? 1337 PRO AAA CA   1 
ATOM   1246 C C    . PRO A 1 76  ? -19.357 7.904   31.333 1.000 54.350  ? 1337 PRO AAA C    1 
ATOM   1247 O O    . PRO A 1 76  ? -20.218 7.783   30.444 1.000 51.810  ? 1337 PRO AAA O    1 
ATOM   1248 C CB   . PRO A 1 76  ? -17.711 6.123   32.109 1.000 54.820  ? 1337 PRO AAA CB   1 
ATOM   1249 C CG   . PRO A 1 76  ? -16.195 5.948   32.018 1.000 56.400  ? 1337 PRO AAA CG   1 
ATOM   1250 C CD   . PRO A 1 76  ? -15.671 7.370   31.917 1.000 57.310  ? 1337 PRO AAA CD   1 
ATOM   1251 H HA   . PRO A 1 76  ? -17.927 6.950   30.186 1.000 57.400  ? 1337 PRO AAA HA   1 
ATOM   1252 H HB2  . PRO A 1 76  ? -18.002 6.364   33.013 1.000 54.820  ? 1337 PRO AAA HB2  1 
ATOM   1253 H HB3  . PRO A 1 76  ? -18.194 5.313   31.844 1.000 54.820  ? 1337 PRO AAA HB3  1 
ATOM   1254 H HG2  . PRO A 1 76  ? -15.848 5.491   32.812 1.000 56.400  ? 1337 PRO AAA HG2  1 
ATOM   1255 H HG3  . PRO A 1 76  ? -15.952 5.417   31.231 1.000 56.400  ? 1337 PRO AAA HG3  1 
ATOM   1256 H HD2  . PRO A 1 76  ? -15.384 7.700   32.794 1.000 57.310  ? 1337 PRO AAA HD2  1 
ATOM   1257 H HD3  . PRO A 1 76  ? -14.903 7.417   31.309 1.000 57.310  ? 1337 PRO AAA HD3  1 
ATOM   1258 N N    . SER A 1 77  ? -19.538 8.578   32.467 1.000 49.890  ? 1338 SER AAA N    1 
ATOM   1259 C CA   . SER A 1 77  ? -20.792 9.272   32.874 1.000 55.330  ? 1338 SER AAA CA   1 
ATOM   1260 C C    . SER A 1 77  ? -21.119 10.382  31.875 1.000 52.100  ? 1338 SER AAA C    1 
ATOM   1261 O O    . SER A 1 77  ? -22.311 10.668  31.688 1.000 54.030  ? 1338 SER AAA O    1 
ATOM   1262 C CB   . SER A 1 77  ? -20.674 9.833   34.267 1.000 54.310  ? 1338 SER AAA CB   1 
ATOM   1263 O OG   . SER A 1 77  ? -19.313 10.141  34.580 1.000 61.260  ? 1338 SER AAA OG   1 
ATOM   1264 H H    . SER A 1 77  ? -18.739 8.603   33.084 1.000 49.890  ? 1338 SER AAA H    1 
ATOM   1265 H HA   . SER A 1 77  ? -21.532 8.607   32.855 1.000 55.330  ? 1338 SER AAA HA   1 
ATOM   1266 H HB2  . SER A 1 77  ? -21.218 10.650  34.336 1.000 54.310  ? 1338 SER AAA HB2  1 
ATOM   1267 H HB3  . SER A 1 77  ? -21.016 9.174   34.913 1.000 54.310  ? 1338 SER AAA HB3  1 
ATOM   1268 H HG   . SER A 1 77  ? -19.282 10.453  35.366 0.000 61.260  ? 1338 SER AAA HG   1 
ATOM   1269 N N    . GLU A 1 78  ? -20.089 11.003  31.297 1.000 52.360  ? 1339 GLU AAA N    1 
ATOM   1270 C CA   . GLU A 1 78  ? -20.237 12.061  30.254 1.000 65.170  ? 1339 GLU AAA CA   1 
ATOM   1271 C C    . GLU A 1 78  ? -20.716 11.401  28.937 1.000 59.560  ? 1339 GLU AAA C    1 
ATOM   1272 O O    . GLU A 1 78  ? -21.772 11.824  28.382 1.000 53.140  ? 1339 GLU AAA O    1 
ATOM   1273 C CB   . GLU A 1 78  ? -18.921 12.854  30.211 1.000 70.250  ? 1339 GLU AAA CB   1 
ATOM   1274 C CG   . GLU A 1 78  ? -18.695 13.697  28.969 1.000 86.190  ? 1339 GLU AAA CG   1 
ATOM   1275 C CD   . GLU A 1 78  ? -19.745 14.747  28.650 1.000 92.310  ? 1339 GLU AAA CD   1 
ATOM   1276 O OE1  . GLU A 1 78  ? -20.634 14.960  29.506 1.000 86.100  ? 1339 GLU AAA OE1  1 
ATOM   1277 O OE2  . GLU A 1 78  ? -19.677 15.341  27.529 1.000 95.880  ? 1339 GLU AAA OE2  1 
ATOM   1278 H H    . GLU A 1 78  ? -19.163 10.730  31.593 1.000 52.360  ? 1339 GLU AAA H    1 
ATOM   1279 H HA   . GLU A 1 78  ? -20.918 12.705  30.557 1.000 65.170  ? 1339 GLU AAA HA   1 
ATOM   1280 H HB2  . GLU A 1 78  ? -18.893 13.454  30.986 1.000 70.250  ? 1339 GLU AAA HB2  1 
ATOM   1281 H HB3  . GLU A 1 78  ? -18.174 12.223  30.281 1.000 70.250  ? 1339 GLU AAA HB3  1 
ATOM   1282 H HG2  . GLU A 1 78  ? -17.836 14.163  29.053 1.000 86.190  ? 1339 GLU AAA HG2  1 
ATOM   1283 H HG3  . GLU A 1 78  ? -18.632 13.104  28.190 1.000 86.190  ? 1339 GLU AAA HG3  1 
ATOM   1284 N N    . LEU A 1 79  ? -20.011 10.354  28.499 1.000 49.600  ? 1340 LEU AAA N    1 
ATOM   1285 C CA   . LEU A 1 79  ? -20.356 9.532   27.310 1.000 50.390  ? 1340 LEU AAA CA   1 
ATOM   1286 C C    . LEU A 1 79  ? -21.798 9.017   27.372 1.000 48.800  ? 1340 LEU AAA C    1 
ATOM   1287 O O    . LEU A 1 79  ? -22.502 9.143   26.384 1.000 49.180  ? 1340 LEU AAA O    1 
ATOM   1288 C CB   . LEU A 1 79  ? -19.363 8.375   27.258 1.000 48.300  ? 1340 LEU AAA CB   1 
ATOM   1289 C CG   . LEU A 1 79  ? -17.921 8.776   26.943 1.000 47.330  ? 1340 LEU AAA CG   1 
ATOM   1290 C CD1  . LEU A 1 79  ? -17.042 7.535   26.838 1.000 42.020  ? 1340 LEU AAA CD1  1 
ATOM   1291 C CD2  . LEU A 1 79  ? -17.842 9.595   25.652 1.000 48.840  ? 1340 LEU AAA CD2  1 
ATOM   1292 H H    . LEU A 1 79  ? -19.186 10.124  29.034 1.000 49.600  ? 1340 LEU AAA H    1 
ATOM   1293 H HA   . LEU A 1 79  ? -20.276 10.096  26.506 1.000 50.390  ? 1340 LEU AAA HA   1 
ATOM   1294 H HB2  . LEU A 1 79  ? -19.380 7.916   28.121 1.000 48.300  ? 1340 LEU AAA HB2  1 
ATOM   1295 H HB3  . LEU A 1 79  ? -19.667 7.739   26.580 1.000 48.300  ? 1340 LEU AAA HB3  1 
ATOM   1296 H HG   . LEU A 1 79  ? -17.592 9.344   27.683 1.000 47.330  ? 1340 LEU AAA HG   1 
ATOM   1297 H HD11 . LEU A 1 79  ? -17.062 7.051   27.682 1.000 42.020  ? 1340 LEU AAA HD11 1 
ATOM   1298 H HD12 . LEU A 1 79  ? -16.128 7.801   26.637 1.000 42.020  ? 1340 LEU AAA HD12 1 
ATOM   1299 H HD13 . LEU A 1 79  ? -17.376 6.960   26.127 1.000 42.020  ? 1340 LEU AAA HD13 1 
ATOM   1300 H HD21 . LEU A 1 79  ? -18.186 9.067   24.911 1.000 48.840  ? 1340 LEU AAA HD21 1 
ATOM   1301 H HD22 . LEU A 1 79  ? -16.916 9.837   25.477 1.000 48.840  ? 1340 LEU AAA HD22 1 
ATOM   1302 H HD23 . LEU A 1 79  ? -18.375 10.404  25.748 1.000 48.840  ? 1340 LEU AAA HD23 1 
ATOM   1303 N N    . ARG A 1 80  ? -22.220 8.473   28.511 1.000 51.930  ? 1341 ARG AAA N    1 
ATOM   1304 C CA   . ARG A 1 80  ? -23.588 7.931   28.725 1.000 46.240  ? 1341 ARG AAA CA   1 
ATOM   1305 C C    . ARG A 1 80  ? -24.611 9.072   28.648 1.000 47.970  ? 1341 ARG AAA C    1 
ATOM   1306 O O    . ARG A 1 80  ? -25.715 8.859   28.057 1.000 54.460  ? 1341 ARG AAA O    1 
ATOM   1307 C CB   . ARG A 1 80  ? -23.668 7.181   30.066 1.000 47.020  ? 1341 ARG AAA CB   1 
ATOM   1308 C CG   . ARG A 1 80  ? -22.870 5.877   30.141 1.000 49.670  ? 1341 ARG AAA CG   1 
ATOM   1309 C CD   . ARG A 1 80  ? -23.380 4.898   31.202 1.000 49.810  ? 1341 ARG AAA CD   1 
ATOM   1310 N NE   . ARG A 1 80  ? -23.553 5.679   32.414 1.000 51.550  ? 1341 ARG AAA NE   1 
ATOM   1311 C CZ   . ARG A 1 80  ? -22.587 5.913   33.297 1.000 49.500  ? 1341 ARG AAA CZ   1 
ATOM   1312 N NH1  . ARG A 1 80  ? -21.394 5.348   33.167 1.000 46.270  ? 1341 ARG AAA NH1  1 
ATOM   1313 N NH2  . ARG A 1 80  ? -22.830 6.699   34.323 1.000 47.440  ? 1341 ARG AAA NH2  1 
ATOM   1314 H H    . ARG A 1 80  ? -21.552 8.436   29.267 1.000 51.930  ? 1341 ARG AAA H    1 
ATOM   1315 H HA   . ARG A 1 80  ? -23.783 7.284   28.009 1.000 46.240  ? 1341 ARG AAA HA   1 
ATOM   1316 H HB2  . ARG A 1 80  ? -23.346 7.775   30.775 1.000 47.020  ? 1341 ARG AAA HB2  1 
ATOM   1317 H HB3  . ARG A 1 80  ? -24.608 6.973   30.251 1.000 47.020  ? 1341 ARG AAA HB3  1 
ATOM   1318 H HG2  . ARG A 1 80  ? -22.902 5.428   29.270 1.000 49.670  ? 1341 ARG AAA HG2  1 
ATOM   1319 H HG3  . ARG A 1 80  ? -21.932 6.083   30.340 1.000 49.670  ? 1341 ARG AAA HG3  1 
ATOM   1320 H HD2  . ARG A 1 80  ? -24.220 4.496   30.893 1.000 49.810  ? 1341 ARG AAA HD2  1 
ATOM   1321 H HD3  . ARG A 1 80  ? -22.728 4.174   31.313 1.000 49.810  ? 1341 ARG AAA HD3  1 
ATOM   1322 H HE   . ARG A 1 80  ? -24.341 6.016   32.573 1.000 51.550  ? 1341 ARG AAA HE   1 
ATOM   1323 H HH11 . ARG A 1 80  ? -21.236 4.811   32.489 1.000 46.270  ? 1341 ARG AAA HH11 1 
ATOM   1324 H HH12 . ARG A 1 80  ? -20.765 5.512   33.759 1.000 46.270  ? 1341 ARG AAA HH12 1 
ATOM   1325 H HH21 . ARG A 1 80  ? -23.627 7.063   34.418 1.000 47.440  ? 1341 ARG AAA HH21 1 
ATOM   1326 H HH22 . ARG A 1 80  ? -22.195 6.859   34.913 1.000 47.440  ? 1341 ARG AAA HH22 1 
ATOM   1327 N N    . ARG A 1 81  ? -24.301 10.229  29.232 1.000 49.800  ? 1342 ARG AAA N    1 
ATOM   1328 C CA   . ARG A 1 81  ? -25.185 11.426  29.152 1.000 58.940  ? 1342 ARG AAA CA   1 
ATOM   1329 C C    . ARG A 1 81  ? -25.374 11.850  27.685 1.000 52.830  ? 1342 ARG AAA C    1 
ATOM   1330 O O    . ARG A 1 81  ? -26.503 12.177  27.299 1.000 48.060  ? 1342 ARG AAA O    1 
ATOM   1331 C CB   . ARG A 1 81  ? -24.608 12.592  29.954 1.000 63.430  ? 1342 ARG AAA CB   1 
ATOM   1332 C CG   . ARG A 1 81  ? -25.610 13.716  30.201 1.000 71.730  ? 1342 ARG AAA CG   1 
ATOM   1333 C CD   . ARG A 1 81  ? -24.959 14.934  30.845 1.000 82.830  ? 1342 ARG AAA CD   1 
ATOM   1334 N NE   . ARG A 1 81  ? -23.674 15.292  30.233 1.000 89.820  ? 1342 ARG AAA NE   1 
ATOM   1335 C CZ   . ARG A 1 81  ? -23.519 15.921  29.059 1.000 93.720  ? 1342 ARG AAA CZ   1 
ATOM   1336 N NH1  . ARG A 1 81  ? -24.564 16.298  28.334 1.000 98.140  ? 1342 ARG AAA NH1  1 
ATOM   1337 N NH2  . ARG A 1 81  ? -22.306 16.177  28.610 1.000 85.430  ? 1342 ARG AAA NH2  1 
ATOM   1338 H H    . ARG A 1 81  ? -23.434 10.291  29.746 1.000 49.800  ? 1342 ARG AAA H    1 
ATOM   1339 H HA   . ARG A 1 81  ? -26.066 11.189  29.522 1.000 58.940  ? 1342 ARG AAA HA   1 
ATOM   1340 H HB2  . ARG A 1 81  ? -24.290 12.251  30.816 1.000 63.430  ? 1342 ARG AAA HB2  1 
ATOM   1341 H HB3  . ARG A 1 81  ? -23.836 12.952  29.469 1.000 63.430  ? 1342 ARG AAA HB3  1 
ATOM   1342 H HG2  . ARG A 1 81  ? -26.015 13.982  29.348 1.000 71.730  ? 1342 ARG AAA HG2  1 
ATOM   1343 H HG3  . ARG A 1 81  ? -26.326 13.388  30.786 1.000 71.730  ? 1342 ARG AAA HG3  1 
ATOM   1344 H HD2  . ARG A 1 81  ? -25.567 15.700  30.774 1.000 82.830  ? 1342 ARG AAA HD2  1 
ATOM   1345 H HD3  . ARG A 1 81  ? -24.816 14.757  31.799 1.000 82.830  ? 1342 ARG AAA HD3  1 
ATOM   1346 H HE   . ARG A 1 81  ? -22.945 15.081  30.663 1.000 89.820  ? 1342 ARG AAA HE   1 
ATOM   1347 H HH11 . ARG A 1 81  ? -25.378 16.136  28.623 1.000 98.140  ? 1342 ARG AAA HH11 1 
ATOM   1348 H HH12 . ARG A 1 81  ? -24.439 16.709  27.567 1.000 98.140  ? 1342 ARG AAA HH12 1 
ATOM   1349 H HH21 . ARG A 1 81  ? -21.603 15.934  29.082 1.000 85.430  ? 1342 ARG AAA HH21 1 
ATOM   1350 H HH22 . ARG A 1 81  ? -22.202 16.590  27.839 1.000 85.430  ? 1342 ARG AAA HH22 1 
ATOM   1351 N N    . ILE A 1 82  ? -24.303 11.847  26.895 1.000 54.930  ? 1343 ILE AAA N    1 
ATOM   1352 C CA   . ILE A 1 82  ? -24.355 12.190  25.441 1.000 52.780  ? 1343 ILE AAA CA   1 
ATOM   1353 C C    . ILE A 1 82  ? -25.293 11.212  24.716 1.000 50.800  ? 1343 ILE AAA C    1 
ATOM   1354 O O    . ILE A 1 82  ? -26.211 11.664  23.981 1.000 47.300  ? 1343 ILE AAA O    1 
ATOM   1355 C CB   . ILE A 1 82  ? -22.939 12.176  24.847 1.000 54.180  ? 1343 ILE AAA CB   1 
ATOM   1356 C CG1  . ILE A 1 82  ? -22.096 13.324  25.406 1.000 50.450  ? 1343 ILE AAA CG1  1 
ATOM   1357 C CG2  . ILE A 1 82  ? -23.007 12.189  23.326 1.000 57.920  ? 1343 ILE AAA CG2  1 
ATOM   1358 C CD1  . ILE A 1 82  ? -20.681 13.376  24.839 1.000 54.650  ? 1343 ILE AAA CD1  1 
ATOM   1359 H H    . ILE A 1 82  ? -23.417 11.599  27.311 1.000 54.930  ? 1343 ILE AAA H    1 
ATOM   1360 H HA   . ILE A 1 82  ? -24.722 13.088  25.350 1.000 52.780  ? 1343 ILE AAA HA   1 
ATOM   1361 H HB   . ILE A 1 82  ? -22.510 11.329  25.124 1.000 54.180  ? 1343 ILE AAA HB   1 
ATOM   1362 H HG12 . ILE A 1 82  ? -22.549 14.172  25.209 1.000 50.450  ? 1343 ILE AAA HG12 1 
ATOM   1363 H HG13 . ILE A 1 82  ? -22.044 13.230  26.381 1.000 50.450  ? 1343 ILE AAA HG13 1 
ATOM   1364 H HG21 . ILE A 1 82  ? -23.488 11.403  23.013 1.000 57.920  ? 1343 ILE AAA HG21 1 
ATOM   1365 H HG22 . ILE A 1 82  ? -22.106 12.177  22.958 1.000 57.920  ? 1343 ILE AAA HG22 1 
ATOM   1366 H HG23 . ILE A 1 82  ? -23.469 12.991  23.026 1.000 57.920  ? 1343 ILE AAA HG23 1 
ATOM   1367 H HD11 . ILE A 1 82  ? -20.216 12.547  25.048 1.000 54.650  ? 1343 ILE AAA HD11 1 
ATOM   1368 H HD12 . ILE A 1 82  ? -20.200 14.124  25.233 1.000 54.650  ? 1343 ILE AAA HD12 1 
ATOM   1369 H HD13 . ILE A 1 82  ? -20.721 13.490  23.873 1.000 54.650  ? 1343 ILE AAA HD13 1 
ATOM   1370 N N    . ALA A 1 83  ? -25.088 9.912   24.929 1.000 48.420  ? 1344 ALA AAA N    1 
ATOM   1371 C CA   . ALA A 1 83  ? -25.922 8.843   24.340 1.000 48.320  ? 1344 ALA AAA CA   1 
ATOM   1372 C C    . ALA A 1 83  ? -27.391 9.069   24.710 1.000 48.060  ? 1344 ALA AAA C    1 
ATOM   1373 O O    . ALA A 1 83  ? -28.216 8.938   23.827 1.000 46.440  ? 1344 ALA AAA O    1 
ATOM   1374 C CB   . ALA A 1 83  ? -25.413 7.502   24.785 1.000 51.570  ? 1344 ALA AAA CB   1 
ATOM   1375 H H    . ALA A 1 83  ? -24.316 9.660   25.529 1.000 48.420  ? 1344 ALA AAA H    1 
ATOM   1376 H HA   . ALA A 1 83  ? -25.837 8.884   23.359 1.000 48.320  ? 1344 ALA AAA HA   1 
ATOM   1377 H HB1  . ALA A 1 83  ? -25.961 6.802   24.398 1.000 51.570  ? 1344 ALA AAA HB1  1 
ATOM   1378 H HB2  . ALA A 1 83  ? -24.495 7.390   24.493 1.000 51.570  ? 1344 ALA AAA HB2  1 
ATOM   1379 H HB3  . ALA A 1 83  ? -25.453 7.444   25.754 1.000 51.570  ? 1344 ALA AAA HB3  1 
ATOM   1380 N N    . SER A 1 84  ? -27.705 9.444   25.958 1.000 50.170  ? 1345 SER AAA N    1 
ATOM   1381 C CA   . SER A 1 84  ? -29.109 9.644   26.416 1.000 51.770  ? 1345 SER AAA CA   1 
ATOM   1382 C C    . SER A 1 84  ? -29.715 10.864  25.744 1.000 51.520  ? 1345 SER AAA C    1 
ATOM   1383 O O    . SER A 1 84  ? -30.943 10.993  25.813 1.000 53.360  ? 1345 SER AAA O    1 
ATOM   1384 C CB   . SER A 1 84  ? -29.217 9.810   27.895 1.000 56.320  ? 1345 SER AAA CB   1 
ATOM   1385 O OG   . SER A 1 84  ? -28.506 10.968  28.325 1.000 56.070  ? 1345 SER AAA OG   1 
ATOM   1386 H H    . SER A 1 84  ? -26.948 9.595   26.610 1.000 50.170  ? 1345 SER AAA H    1 
ATOM   1387 H HA   . SER A 1 84  ? -29.639 8.847   26.143 1.000 51.770  ? 1345 SER AAA HA   1 
ATOM   1388 H HB2  . SER A 1 84  ? -30.165 9.896   28.144 1.000 56.320  ? 1345 SER AAA HB2  1 
ATOM   1389 H HB3  . SER A 1 84  ? -28.847 9.014   28.340 1.000 56.320  ? 1345 SER AAA HB3  1 
ATOM   1390 H HG   . SER A 1 84  ? -28.585 11.036  29.165 0.000 56.070  ? 1345 SER AAA HG   1 
ATOM   1391 N N    . GLN A 1 85  ? -28.887 11.737  25.160 1.000 58.300  ? 1346 GLN AAA N    1 
ATOM   1392 C CA   . GLN A 1 85  ? -29.362 13.027  24.594 1.000 60.950  ? 1346 GLN AAA CA   1 
ATOM   1393 C C    . GLN A 1 85  ? -29.290 13.017  23.062 1.000 53.670  ? 1346 GLN AAA C    1 
ATOM   1394 O O    . GLN A 1 85  ? -29.653 14.024  22.484 1.000 56.650  ? 1346 GLN AAA O    1 
ATOM   1395 C CB   . GLN A 1 85  ? -28.620 14.181  25.266 1.000 60.930  ? 1346 GLN AAA CB   1 
ATOM   1396 C CG   . GLN A 1 85  ? -29.324 14.667  26.534 1.000 64.340  ? 1346 GLN AAA CG   1 
ATOM   1397 C CD   . GLN A 1 85  ? -28.384 15.398  27.468 1.000 78.980  ? 1346 GLN AAA CD   1 
ATOM   1398 O OE1  . GLN A 1 85  ? -27.193 15.554  27.202 1.000 79.350  ? 1346 GLN AAA OE1  1 
ATOM   1399 N NE2  . GLN A 1 85  ? -28.903 15.847  28.597 1.000 81.060  ? 1346 GLN AAA NE2  1 
ATOM   1400 H H    . GLN A 1 85  ? -27.905 11.507  25.104 1.000 58.300  ? 1346 GLN AAA H    1 
ATOM   1401 H HA   . GLN A 1 85  ? -30.304 13.154  24.853 1.000 60.950  ? 1346 GLN AAA HA   1 
ATOM   1402 H HB2  . GLN A 1 85  ? -27.713 13.883  25.485 1.000 60.930  ? 1346 GLN AAA HB2  1 
ATOM   1403 H HB3  . GLN A 1 85  ? -28.546 14.919  24.625 1.000 60.930  ? 1346 GLN AAA HB3  1 
ATOM   1404 H HG2  . GLN A 1 85  ? -30.059 15.267  26.285 1.000 64.340  ? 1346 GLN AAA HG2  1 
ATOM   1405 H HG3  . GLN A 1 85  ? -29.709 13.897  27.005 1.000 64.340  ? 1346 GLN AAA HG3  1 
ATOM   1406 H HE21 . GLN A 1 85  ? -28.395 16.281  29.176 0.000 81.060  ? 1346 GLN AAA HE21 1 
ATOM   1407 H HE22 . GLN A 1 85  ? -29.759 15.714  28.774 0.000 81.060  ? 1346 GLN AAA HE22 1 
ATOM   1408 N N    . VAL A 1 86  ? -28.972 11.894  22.422 1.000 46.710  ? 1347 VAL AAA N    1 
ATOM   1409 C CA   . VAL A 1 86  ? -29.102 11.748  20.941 1.000 49.890  ? 1347 VAL AAA CA   1 
ATOM   1410 C C    . VAL A 1 86  ? -30.513 12.198  20.533 1.000 48.780  ? 1347 VAL AAA C    1 
ATOM   1411 O O    . VAL A 1 86  ? -31.443 11.807  21.234 1.000 45.000  ? 1347 VAL AAA O    1 
ATOM   1412 C CB   . VAL A 1 86  ? -28.839 10.304  20.500 1.000 49.210  ? 1347 VAL AAA CB   1 
ATOM   1413 C CG1  . VAL A 1 86  ? -29.266 10.095  19.053 1.000 52.130  ? 1347 VAL AAA CG1  1 
ATOM   1414 C CG2  . VAL A 1 86  ? -27.386 9.899   20.715 1.000 48.890  ? 1347 VAL AAA CG2  1 
ATOM   1415 H H    . VAL A 1 86  ? -28.630 11.114  22.966 1.000 46.710  ? 1347 VAL AAA H    1 
ATOM   1416 H HA   . VAL A 1 86  ? -28.451 12.335  20.516 1.000 49.890  ? 1347 VAL AAA HA   1 
ATOM   1417 H HB   . VAL A 1 86  ? -29.399 9.718   21.067 1.000 49.210  ? 1347 VAL AAA HB   1 
ATOM   1418 H HG11 . VAL A 1 86  ? -30.217 10.282  18.965 1.000 52.130  ? 1347 VAL AAA HG11 1 
ATOM   1419 H HG12 . VAL A 1 86  ? -29.091 9.174   18.792 1.000 52.130  ? 1347 VAL AAA HG12 1 
ATOM   1420 H HG13 . VAL A 1 86  ? -28.763 10.696  18.476 1.000 52.130  ? 1347 VAL AAA HG13 1 
ATOM   1421 H HG21 . VAL A 1 86  ? -26.806 10.485  20.199 1.000 48.890  ? 1347 VAL AAA HG21 1 
ATOM   1422 H HG22 . VAL A 1 86  ? -27.259 8.979   20.425 1.000 48.890  ? 1347 VAL AAA HG22 1 
ATOM   1423 H HG23 . VAL A 1 86  ? -27.164 9.974   21.659 1.000 48.890  ? 1347 VAL AAA HG23 1 
ATOM   1424 N N    . LYS A 1 87  ? -30.651 13.029  19.492 1.000 50.050  ? 1348 LYS AAA N    1 
ATOM   1425 C CA   . LYS A 1 87  ? -31.943 13.661  19.076 1.000 54.010  ? 1348 LYS AAA CA   1 
ATOM   1426 C C    . LYS A 1 87  ? -32.748 12.692  18.194 1.000 54.990  ? 1348 LYS AAA C    1 
ATOM   1427 O O    . LYS A 1 87  ? -32.124 11.906  17.422 1.000 53.250  ? 1348 LYS AAA O    1 
ATOM   1428 C CB   . LYS A 1 87  ? -31.687 14.977  18.322 1.000 61.020  ? 1348 LYS AAA CB   1 
ATOM   1429 C CG   . LYS A 1 87  ? -32.705 16.103  18.523 1.000 74.470  ? 1348 LYS AAA CG   1 
ATOM   1430 C CD   . LYS A 1 87  ? -34.154 15.693  18.955 1.000 88.950  ? 1348 LYS AAA CD   1 
ATOM   1431 C CE   . LYS A 1 87  ? -34.341 15.454  20.456 1.000 81.520  ? 1348 LYS AAA CE   1 
ATOM   1432 N NZ   . LYS A 1 87  ? -35.263 14.336  20.797 1.000 65.810  ? 1348 LYS AAA NZ   1 
ATOM   1433 H H    . LYS A 1 87  ? -29.813 13.229  18.965 1.000 50.050  ? 1348 LYS AAA H    1 
ATOM   1434 H HA   . LYS A 1 87  ? -32.470 13.855  19.885 1.000 54.010  ? 1348 LYS AAA HA   1 
ATOM   1435 H HB2  . LYS A 1 87  ? -30.807 15.320  18.583 1.000 61.020  ? 1348 LYS AAA HB2  1 
ATOM   1436 H HB3  . LYS A 1 87  ? -31.642 14.783  17.362 1.000 61.020  ? 1348 LYS AAA HB3  1 
ATOM   1437 H HG2  . LYS A 1 87  ? -32.366 16.712  19.214 1.000 74.470  ? 1348 LYS AAA HG2  1 
ATOM   1438 H HG3  . LYS A 1 87  ? -32.791 16.601  17.682 1.000 74.470  ? 1348 LYS AAA HG3  1 
ATOM   1439 H HD2  . LYS A 1 87  ? -34.780 16.397  18.683 1.000 88.950  ? 1348 LYS AAA HD2  1 
ATOM   1440 H HD3  . LYS A 1 87  ? -34.407 14.869  18.486 1.000 88.950  ? 1348 LYS AAA HD3  1 
ATOM   1441 H HE2  . LYS A 1 87  ? -33.477 15.257  20.866 1.000 81.520  ? 1348 LYS AAA HE2  1 
ATOM   1442 H HE3  . LYS A 1 87  ? -34.694 16.262  20.874 1.000 81.520  ? 1348 LYS AAA HE3  1 
ATOM   1443 H HZ1  . LYS A 1 87  ? -36.086 14.501  20.454 1.000 65.810  ? 1348 LYS AAA HZ1  1 
ATOM   1444 H HZ2  . LYS A 1 87  ? -35.323 14.252  21.698 1.000 65.810  ? 1348 LYS AAA HZ2  1 
ATOM   1445 H HZ3  . LYS A 1 87  ? -34.947 13.561  20.448 1.000 65.810  ? 1348 LYS AAA HZ3  1 
ATOM   1446 N N    . TYR A 1 88  ? -34.082 12.696  18.325 1.000 52.190  ? 1349 TYR AAA N    1 
ATOM   1447 C CA   . TYR A 1 88  ? -35.012 11.986  17.406 1.000 51.400  ? 1349 TYR AAA CA   1 
ATOM   1448 C C    . TYR A 1 88  ? -34.952 12.676  16.044 1.000 51.930  ? 1349 TYR AAA C    1 
ATOM   1449 O O    . TYR A 1 88  ? -35.125 13.891  16.017 1.000 54.560  ? 1349 TYR AAA O    1 
ATOM   1450 C CB   . TYR A 1 88  ? -36.443 11.976  17.943 1.000 46.620  ? 1349 TYR AAA CB   1 
ATOM   1451 C CG   . TYR A 1 88  ? -37.429 11.196  17.109 1.000 45.860  ? 1349 TYR AAA CG   1 
ATOM   1452 C CD1  . TYR A 1 88  ? -37.242 9.847   16.864 1.000 48.550  ? 1349 TYR AAA CD1  1 
ATOM   1453 C CD2  . TYR A 1 88  ? -38.569 11.791  16.575 1.000 48.160  ? 1349 TYR AAA CD2  1 
ATOM   1454 C CE1  . TYR A 1 88  ? -38.143 9.119   16.094 1.000 56.360  ? 1349 TYR AAA CE1  1 
ATOM   1455 C CE2  . TYR A 1 88  ? -39.468 11.085  15.785 1.000 47.650  ? 1349 TYR AAA CE2  1 
ATOM   1456 C CZ   . TYR A 1 88  ? -39.261 9.738   15.555 1.000 50.540  ? 1349 TYR AAA CZ   1 
ATOM   1457 O OH   . TYR A 1 88  ? -40.136 9.017   14.804 1.000 50.870  ? 1349 TYR AAA OH   1 
ATOM   1458 H H    . TYR A 1 88  ? -34.461 13.219  19.102 1.000 52.190  ? 1349 TYR AAA H    1 
ATOM   1459 H HA   . TYR A 1 88  ? -34.706 11.049  17.308 1.000 51.400  ? 1349 TYR AAA HA   1 
ATOM   1460 H HB2  . TYR A 1 88  ? -36.431 11.603  18.849 1.000 46.620  ? 1349 TYR AAA HB2  1 
ATOM   1461 H HB3  . TYR A 1 88  ? -36.754 12.903  18.014 1.000 46.620  ? 1349 TYR AAA HB3  1 
ATOM   1462 H HD1  . TYR A 1 88  ? -36.487 9.413   17.225 1.000 48.550  ? 1349 TYR AAA HD1  1 
ATOM   1463 H HD2  . TYR A 1 88  ? -38.733 12.702  16.757 1.000 48.160  ? 1349 TYR AAA HD2  1 
ATOM   1464 H HE1  . TYR A 1 88  ? -37.999 8.200   15.938 1.000 56.360  ? 1349 TYR AAA HE1  1 
ATOM   1465 H HE2  . TYR A 1 88  ? -40.225 11.514  15.423 1.000 47.650  ? 1349 TYR AAA HE2  1 
ATOM   1466 H HH   . TYR A 1 88  ? -40.463 8.375   15.270 0.000 50.870  ? 1349 TYR AAA HH   1 
ATOM   1467 N N    . ALA A 1 89  ? -34.676 11.931  14.978 1.000 47.770  ? 1350 ALA AAA N    1 
ATOM   1468 C CA   . ALA A 1 89  ? -34.709 12.448  13.598 1.000 50.750  ? 1350 ALA AAA CA   1 
ATOM   1469 C C    . ALA A 1 89  ? -36.097 12.173  13.009 1.000 55.750  ? 1350 ALA AAA C    1 
ATOM   1470 O O    . ALA A 1 89  ? -36.702 13.119  12.503 1.000 61.430  ? 1350 ALA AAA O    1 
ATOM   1471 C CB   . ALA A 1 89  ? -33.611 11.850  12.773 1.000 50.130  ? 1350 ALA AAA CB   1 
ATOM   1472 H H    . ALA A 1 89  ? -34.433 10.963  15.136 1.000 47.770  ? 1350 ALA AAA H    1 
ATOM   1473 H HA   . ALA A 1 89  ? -34.557 13.422  13.625 1.000 50.750  ? 1350 ALA AAA HA   1 
ATOM   1474 H HB1  . ALA A 1 89  ? -33.653 12.204  11.871 1.000 50.130  ? 1350 ALA AAA HB1  1 
ATOM   1475 H HB2  . ALA A 1 89  ? -32.752 12.071  13.166 1.000 50.130  ? 1350 ALA AAA HB2  1 
ATOM   1476 H HB3  . ALA A 1 89  ? -33.714 10.884  12.745 1.000 50.130  ? 1350 ALA AAA HB3  1 
ATOM   1477 N N    . GLY A 1 90  ? -36.618 10.952  13.134 1.000 59.330  ? 1351 GLY AAA N    1 
ATOM   1478 C CA   . GLY A 1 90  ? -37.932 10.580  12.563 1.000 64.780  ? 1351 GLY AAA CA   1 
ATOM   1479 C C    . GLY A 1 90  ? -37.925 10.722  11.044 1.000 58.780  ? 1351 GLY AAA C    1 
ATOM   1480 O O    . GLY A 1 90  ? -38.961 11.054  10.468 1.000 60.020  ? 1351 GLY AAA O    1 
ATOM   1481 H H    . GLY A 1 90  ? -36.087 10.258  13.641 1.000 59.330  ? 1351 GLY AAA H    1 
ATOM   1482 H HA2  . GLY A 1 90  ? -38.140 9.645   12.812 1.000 64.780  ? 1351 GLY AAA HA2  1 
ATOM   1483 H HA3  . GLY A 1 90  ? -38.630 11.164  12.952 1.000 64.780  ? 1351 GLY AAA HA3  1 
ATOM   1484 N N    . SER A 1 91  ? -36.772 10.456  10.438 1.000 55.170  ? 1352 SER AAA N    1 
ATOM   1485 C CA   . SER A 1 91  ? -36.481 10.639  9.003  1.000 59.620  ? 1352 SER AAA CA   1 
ATOM   1486 C C    . SER A 1 91  ? -37.316 9.658   8.177  1.000 59.030  ? 1352 SER AAA C    1 
ATOM   1487 O O    . SER A 1 91  ? -37.812 8.659   8.697  1.000 66.810  ? 1352 SER AAA O    1 
ATOM   1488 C CB   . SER A 1 91  ? -34.998 10.512  8.709  1.000 56.900  ? 1352 SER AAA CB   1 
ATOM   1489 O OG   . SER A 1 91  ? -34.592 9.158   8.801  1.000 60.540  ? 1352 SER AAA OG   1 
ATOM   1490 H H    . SER A 1 91  ? -36.049 10.097  11.045 1.000 55.170  ? 1352 SER AAA H    1 
ATOM   1491 H HA   . SER A 1 91  ? -36.746 11.564  8.750  1.000 59.620  ? 1352 SER AAA HA   1 
ATOM   1492 H HB2  . SER A 1 91  ? -34.816 10.851  7.804  1.000 56.900  ? 1352 SER AAA HB2  1 
ATOM   1493 H HB3  . SER A 1 91  ? -34.491 11.054  9.355  1.000 56.900  ? 1352 SER AAA HB3  1 
ATOM   1494 H HG   . SER A 1 91  ? -33.764 9.114   8.633  0.000 60.540  ? 1352 SER AAA HG   1 
ATOM   1495 N N    . GLN A 1 92  ? -37.440 9.995   6.909  1.000 59.710  ? 1353 GLN AAA N    1 
ATOM   1496 C CA   . GLN A 1 92  ? -38.229 9.304   5.871  1.000 63.860  ? 1353 GLN AAA CA   1 
ATOM   1497 C C    . GLN A 1 92  ? -37.504 7.969   5.625  1.000 58.430  ? 1353 GLN AAA C    1 
ATOM   1498 O O    . GLN A 1 92  ? -38.136 6.929   5.640  1.000 55.030  ? 1353 GLN AAA O    1 
ATOM   1499 C CB   . GLN A 1 92  ? -38.366 10.281  4.675  1.000 77.250  ? 1353 GLN AAA CB   1 
ATOM   1500 C CG   . GLN A 1 92  ? -38.365 11.806  5.020  1.000 79.390  ? 1353 GLN AAA CG   1 
ATOM   1501 C CD   . GLN A 1 92  ? -37.017 12.455  5.320  1.000 75.390  ? 1353 GLN AAA CD   1 
ATOM   1502 O OE1  . GLN A 1 92  ? -35.962 11.848  5.083  1.000 72.640  ? 1353 GLN AAA OE1  1 
ATOM   1503 N NE2  . GLN A 1 92  ? -37.026 13.669  5.883  1.000 51.380  ? 1353 GLN AAA NE2  1 
ATOM   1504 H H    . GLN A 1 92  ? -36.921 10.825  6.662  1.000 59.710  ? 1353 GLN AAA H    1 
ATOM   1505 H HA   . GLN A 1 92  ? -39.136 9.146   6.222  1.000 63.860  ? 1353 GLN AAA HA   1 
ATOM   1506 H HB2  . GLN A 1 92  ? -37.627 10.117  4.052  1.000 77.250  ? 1353 GLN AAA HB2  1 
ATOM   1507 H HB3  . GLN A 1 92  ? -39.203 10.083  4.205  1.000 77.250  ? 1353 GLN AAA HB3  1 
ATOM   1508 H HG2  . GLN A 1 92  ? -38.753 12.307  4.271  1.000 79.390  ? 1353 GLN AAA HG2  1 
ATOM   1509 H HG3  . GLN A 1 92  ? -38.928 11.959  5.809  1.000 79.390  ? 1353 GLN AAA HG3  1 
ATOM   1510 H HE21 . GLN A 1 92  ? -36.264 14.075  6.071  0.000 51.380  ? 1353 GLN AAA HE21 1 
ATOM   1511 H HE22 . GLN A 1 92  ? -37.794 14.065  6.067  0.000 51.380  ? 1353 GLN AAA HE22 1 
ATOM   1512 N N    . VAL A 1 93  ? -36.178 7.998   5.509  1.000 56.700  ? 1354 VAL AAA N    1 
ATOM   1513 C CA   . VAL A 1 93  ? -35.329 6.811   5.196  1.000 56.190  ? 1354 VAL AAA CA   1 
ATOM   1514 C C    . VAL A 1 93  ? -34.223 6.670   6.257  1.000 59.660  ? 1354 VAL AAA C    1 
ATOM   1515 O O    . VAL A 1 93  ? -33.711 7.734   6.765  1.000 54.760  ? 1354 VAL AAA O    1 
ATOM   1516 C CB   . VAL A 1 93  ? -34.726 6.961   3.785  1.000 59.770  ? 1354 VAL AAA CB   1 
ATOM   1517 C CG1  . VAL A 1 93  ? -34.097 8.335   3.585  1.000 64.820  ? 1354 VAL AAA CG1  1 
ATOM   1518 C CG2  . VAL A 1 93  ? -33.714 5.873   3.473  1.000 57.850  ? 1354 VAL AAA CG2  1 
ATOM   1519 H H    . VAL A 1 93  ? -35.737 8.896   5.646  1.000 56.700  ? 1354 VAL AAA H    1 
ATOM   1520 H HA   . VAL A 1 93  ? -35.888 6.014   5.234  1.000 56.190  ? 1354 VAL AAA HA   1 
ATOM   1521 H HB   . VAL A 1 93  ? -35.468 6.869   3.138  1.000 59.770  ? 1354 VAL AAA HB   1 
ATOM   1522 H HG11 . VAL A 1 93  ? -34.775 9.023   3.704  1.000 64.820  ? 1354 VAL AAA HG11 1 
ATOM   1523 H HG12 . VAL A 1 93  ? -33.727 8.395   2.687  1.000 64.820  ? 1354 VAL AAA HG12 1 
ATOM   1524 H HG13 . VAL A 1 93  ? -33.387 8.465   4.237  1.000 64.820  ? 1354 VAL AAA HG13 1 
ATOM   1525 H HG21 . VAL A 1 93  ? -32.986 5.912   4.118  1.000 57.850  ? 1354 VAL AAA HG21 1 
ATOM   1526 H HG22 . VAL A 1 93  ? -33.361 6.006   2.576  1.000 57.850  ? 1354 VAL AAA HG22 1 
ATOM   1527 H HG23 . VAL A 1 93  ? -34.146 5.003   3.525  1.000 57.850  ? 1354 VAL AAA HG23 1 
ATOM   1528 N N    . ALA A 1 94  ? -33.830 5.420   6.556  1.000 52.490  ? 1355 ALA AAA N    1 
ATOM   1529 C CA   . ALA A 1 94  ? -32.600 5.078   7.322  1.000 47.130  ? 1355 ALA AAA CA   1 
ATOM   1530 C C    . ALA A 1 94  ? -31.767 4.102   6.497  1.000 42.680  ? 1355 ALA AAA C    1 
ATOM   1531 O O    . ALA A 1 94  ? -32.183 2.926   6.331  1.000 42.600  ? 1355 ALA AAA O    1 
ATOM   1532 C CB   . ALA A 1 94  ? -32.926 4.516   8.699  1.000 48.980  ? 1355 ALA AAA CB   1 
ATOM   1533 H H    . ALA A 1 94  ? -34.428 4.676   6.227  1.000 52.490  ? 1355 ALA AAA H    1 
ATOM   1534 H HA   . ALA A 1 94  ? -32.080 5.903   7.464  1.000 47.130  ? 1355 ALA AAA HA   1 
ATOM   1535 H HB1  . ALA A 1 94  ? -32.103 4.306   9.167  1.000 48.980  ? 1355 ALA AAA HB1  1 
ATOM   1536 H HB2  . ALA A 1 94  ? -33.427 5.173   9.207  1.000 48.980  ? 1355 ALA AAA HB2  1 
ATOM   1537 H HB3  . ALA A 1 94  ? -33.458 3.708   8.603  1.000 48.980  ? 1355 ALA AAA HB3  1 
ATOM   1538 N N    . SER A 1 95  ? -30.597 4.547   6.040  1.000 41.760  ? 1356 SER AAA N    1 
ATOM   1539 C CA   . SER A 1 95  ? -29.775 3.785   5.065  1.000 48.070  ? 1356 SER AAA CA   1 
ATOM   1540 C C    . SER A 1 95  ? -28.722 2.910   5.780  1.000 45.330  ? 1356 SER AAA C    1 
ATOM   1541 O O    . SER A 1 95  ? -27.701 3.432   6.235  1.000 37.590  ? 1356 SER AAA O    1 
ATOM   1542 C CB   . SER A 1 95  ? -29.150 4.720   4.049  1.000 43.510  ? 1356 SER AAA CB   1 
ATOM   1543 O OG   . SER A 1 95  ? -28.481 3.954   3.055  1.000 44.310  ? 1356 SER AAA OG   1 
ATOM   1544 H H    . SER A 1 95  ? -30.263 5.439   6.375  1.000 41.760  ? 1356 SER AAA H    1 
ATOM   1545 H HA   . SER A 1 95  ? -30.380 3.176   4.562  1.000 48.070  ? 1356 SER AAA HA   1 
ATOM   1546 H HB2  . SER A 1 95  ? -29.854 5.270   3.637  1.000 43.510  ? 1356 SER AAA HB2  1 
ATOM   1547 H HB3  . SER A 1 95  ? -28.513 5.316   4.504  1.000 43.510  ? 1356 SER AAA HB3  1 
ATOM   1548 H HG   . SER A 1 95  ? -28.136 4.485   2.494  0.000 44.310  ? 1356 SER AAA HG   1 
ATOM   1549 N N    . THR A 1 96  ? -28.971 1.609   5.877  1.000 42.350  ? 1357 THR AAA N    1 
ATOM   1550 C CA   . THR A 1 96  ? -27.978 0.639   6.381  1.000 42.620  ? 1357 THR AAA CA   1 
ATOM   1551 C C    . THR A 1 96  ? -26.703 0.753   5.537  1.000 47.500  ? 1357 THR AAA C    1 
ATOM   1552 O O    . THR A 1 96  ? -25.614 0.698   6.121  1.000 46.110  ? 1357 THR AAA O    1 
ATOM   1553 C CB   . THR A 1 96  ? -28.547 -0.784  6.381  1.000 43.300  ? 1357 THR AAA CB   1 
ATOM   1554 O OG1  . THR A 1 96  ? -29.135 -1.101  5.116  1.000 41.300  ? 1357 THR AAA OG1  1 
ATOM   1555 C CG2  . THR A 1 96  ? -29.576 -0.990  7.472  1.000 48.680  ? 1357 THR AAA CG2  1 
ATOM   1556 H H    . THR A 1 96  ? -29.882 1.278   5.591  1.000 42.350  ? 1357 THR AAA H    1 
ATOM   1557 H HA   . THR A 1 96  ? -27.766 0.877   7.313  1.000 42.620  ? 1357 THR AAA HA   1 
ATOM   1558 H HB   . THR A 1 96  ? -27.801 -1.416  6.517  1.000 43.300  ? 1357 THR AAA HB   1 
ATOM   1559 H HG1  . THR A 1 96  ? -29.444 -1.891  5.136  0.000 41.300  ? 1357 THR AAA HG1  1 
ATOM   1560 H HG21 . THR A 1 96  ? -29.166 -0.830  8.341  1.000 48.680  ? 1357 THR AAA HG21 1 
ATOM   1561 H HG22 . THR A 1 96  ? -29.910 -1.904  7.437  1.000 48.680  ? 1357 THR AAA HG22 1 
ATOM   1562 H HG23 . THR A 1 96  ? -30.316 -0.370  7.344  1.000 48.680  ? 1357 THR AAA HG23 1 
ATOM   1563 N N    . SER A 1 97  ? -26.838 0.903   4.217  1.000 45.720  ? 1358 SER AAA N    1 
ATOM   1564 C CA   . SER A 1 97  ? -25.692 0.986   3.271  1.000 47.650  ? 1358 SER AAA CA   1 
ATOM   1565 C C    . SER A 1 97  ? -24.822 2.200   3.618  1.000 44.600  ? 1358 SER AAA C    1 
ATOM   1566 O O    . SER A 1 97  ? -23.610 2.033   3.772  1.000 42.510  ? 1358 SER AAA O    1 
ATOM   1567 C CB   . SER A 1 97  ? -26.142 0.982   1.824  1.000 49.310  ? 1358 SER AAA CB   1 
ATOM   1568 O OG   . SER A 1 97  ? -26.432 -0.356  1.375  1.000 49.140  ? 1358 SER AAA OG   1 
ATOM   1569 H H    . SER A 1 97  ? -27.780 0.962   3.856  1.000 45.720  ? 1358 SER AAA H    1 
ATOM   1570 H HA   . SER A 1 97  ? -25.141 0.165   3.381  1.000 47.650  ? 1358 SER AAA HA   1 
ATOM   1571 H HB2  . SER A 1 97  ? -26.949 1.537   1.733  1.000 49.310  ? 1358 SER AAA HB2  1 
ATOM   1572 H HB3  . SER A 1 97  ? -25.432 1.367   1.262  1.000 49.310  ? 1358 SER AAA HB3  1 
ATOM   1573 H HG   . SER A 1 97  ? -26.679 -0.321  0.567  0.000 49.140  ? 1358 SER AAA HG   1 
ATOM   1574 N N    . GLU A 1 98  ? -25.420 3.361   3.841  1.000 42.250  ? 1359 GLU AAA N    1 
ATOM   1575 C CA   . GLU A 1 98  ? -24.681 4.601   4.197  1.000 42.990  ? 1359 GLU AAA CA   1 
ATOM   1576 C C    . GLU A 1 98  ? -23.984 4.483   5.576  1.000 48.250  ? 1359 GLU AAA C    1 
ATOM   1577 O O    . GLU A 1 98  ? -22.823 4.942   5.719  1.000 46.360  ? 1359 GLU AAA O    1 
ATOM   1578 C CB   . GLU A 1 98  ? -25.660 5.771   4.218  1.000 46.870  ? 1359 GLU AAA CB   1 
ATOM   1579 C CG   . GLU A 1 98  ? -24.988 7.102   4.460  1.000 53.550  ? 1359 GLU AAA CG   1 
ATOM   1580 C CD   . GLU A 1 98  ? -24.119 7.603   3.325  1.000 51.340  ? 1359 GLU AAA CD   1 
ATOM   1581 O OE1  . GLU A 1 98  ? -24.268 7.101   2.208  1.000 51.410  ? 1359 GLU AAA OE1  1 
ATOM   1582 O OE2  . GLU A 1 98  ? -23.285 8.499   3.567  1.000 65.400  ? 1359 GLU AAA OE2  1 
ATOM   1583 H H    . GLU A 1 98  ? -26.426 3.393   3.762  1.000 42.250  ? 1359 GLU AAA H    1 
ATOM   1584 H HA   . GLU A 1 98  ? -23.980 4.751   3.522  1.000 42.990  ? 1359 GLU AAA HA   1 
ATOM   1585 H HB2  . GLU A 1 98  ? -26.129 5.801   3.358  1.000 46.870  ? 1359 GLU AAA HB2  1 
ATOM   1586 H HB3  . GLU A 1 98  ? -26.320 5.613   4.925  1.000 46.870  ? 1359 GLU AAA HB3  1 
ATOM   1587 H HG2  . GLU A 1 98  ? -25.676 7.778   4.638  1.000 53.550  ? 1359 GLU AAA HG2  1 
ATOM   1588 H HG3  . GLU A 1 98  ? -24.430 7.035   5.264  1.000 53.550  ? 1359 GLU AAA HG3  1 
ATOM   1589 N N    . VAL A 1 99  ? -24.655 3.972   6.608  1.000 42.000  ? 1360 VAL AAA N    1 
ATOM   1590 C CA   . VAL A 1 99  ? -24.027 3.964   7.958  1.000 41.130  ? 1360 VAL AAA CA   1 
ATOM   1591 C C    . VAL A 1 99  ? -22.925 2.879   8.007  1.000 39.250  ? 1360 VAL AAA C    1 
ATOM   1592 O O    . VAL A 1 99  ? -21.931 3.104   8.724  1.000 35.070  ? 1360 VAL AAA O    1 
ATOM   1593 C CB   . VAL A 1 99  ? -25.054 3.843   9.090  1.000 41.210  ? 1360 VAL AAA CB   1 
ATOM   1594 C CG1  . VAL A 1 99  ? -25.600 2.416   9.220  1.000 40.230  ? 1360 VAL AAA CG1  1 
ATOM   1595 C CG2  . VAL A 1 99  ? -24.432 4.336   10.408 1.000 42.050  ? 1360 VAL AAA CG2  1 
ATOM   1596 H H    . VAL A 1 99  ? -25.583 3.589   6.494  1.000 42.000  ? 1360 VAL AAA H    1 
ATOM   1597 H HA   . VAL A 1 99  ? -23.608 4.831   8.107  1.000 41.130  ? 1360 VAL AAA HA   1 
ATOM   1598 H HB   . VAL A 1 99  ? -25.814 4.433   8.861  1.000 41.210  ? 1360 VAL AAA HB   1 
ATOM   1599 H HG11 . VAL A 1 99  ? -26.033 2.157   8.388  1.000 40.230  ? 1360 VAL AAA HG11 1 
ATOM   1600 H HG12 . VAL A 1 99  ? -26.246 2.380   9.947  1.000 40.230  ? 1360 VAL AAA HG12 1 
ATOM   1601 H HG13 . VAL A 1 99  ? -24.868 1.804   9.408  1.000 40.230  ? 1360 VAL AAA HG13 1 
ATOM   1602 H HG21 . VAL A 1 99  ? -23.651 3.796   10.621 1.000 42.050  ? 1360 VAL AAA HG21 1 
ATOM   1603 H HG22 . VAL A 1 99  ? -25.086 4.259   11.125 1.000 42.050  ? 1360 VAL AAA HG22 1 
ATOM   1604 H HG23 . VAL A 1 99  ? -24.165 5.267   10.313 1.000 42.050  ? 1360 VAL AAA HG23 1 
ATOM   1605 N N    . LEU A 1 100 ? -23.035 1.806   7.218  1.000 34.610  ? 1361 LEU AAA N    1 
ATOM   1606 C CA   . LEU A 1 100 ? -21.945 0.803   7.102  1.000 40.490  ? 1361 LEU AAA CA   1 
ATOM   1607 C C    . LEU A 1 100 ? -20.763 1.388   6.328  1.000 41.430  ? 1361 LEU AAA C    1 
ATOM   1608 O O    . LEU A 1 100 ? -19.633 1.078   6.702  1.000 42.950  ? 1361 LEU AAA O    1 
ATOM   1609 C CB   . LEU A 1 100 ? -22.434 -0.506  6.469  1.000 39.650  ? 1361 LEU AAA CB   1 
ATOM   1610 C CG   . LEU A 1 100 ? -23.376 -1.324  7.370  1.000 39.230  ? 1361 LEU AAA CG   1 
ATOM   1611 C CD1  . LEU A 1 100 ? -23.820 -2.621  6.712  1.000 39.990  ? 1361 LEU AAA CD1  1 
ATOM   1612 C CD2  . LEU A 1 100 ? -22.744 -1.610  8.723  1.000 42.130  ? 1361 LEU AAA CD2  1 
ATOM   1613 H H    . LEU A 1 100 ? -23.884 1.675   6.686  1.000 34.610  ? 1361 LEU AAA H    1 
ATOM   1614 H HA   . LEU A 1 100 ? -21.636 0.571   8.008  1.000 40.490  ? 1361 LEU AAA HA   1 
ATOM   1615 H HB2  . LEU A 1 100 ? -22.894 -0.290  5.633  1.000 39.650  ? 1361 LEU AAA HB2  1 
ATOM   1616 H HB3  . LEU A 1 100 ? -21.653 -1.049  6.243  1.000 39.650  ? 1361 LEU AAA HB3  1 
ATOM   1617 H HG   . LEU A 1 100 ? -24.193 -0.788  7.526  1.000 39.230  ? 1361 LEU AAA HG   1 
ATOM   1618 H HD11 . LEU A 1 100 ? -24.292 -2.421  5.885  1.000 39.990  ? 1361 LEU AAA HD11 1 
ATOM   1619 H HD12 . LEU A 1 100 ? -24.411 -3.105  7.315  1.000 39.990  ? 1361 LEU AAA HD12 1 
ATOM   1620 H HD13 . LEU A 1 100 ? -23.040 -3.169  6.515  1.000 39.990  ? 1361 LEU AAA HD13 1 
ATOM   1621 H HD21 . LEU A 1 100 ? -21.922 -2.115  8.597  1.000 42.130  ? 1361 LEU AAA HD21 1 
ATOM   1622 H HD22 . LEU A 1 100 ? -23.363 -2.126  9.268  1.000 42.130  ? 1361 LEU AAA HD22 1 
ATOM   1623 H HD23 . LEU A 1 100 ? -22.542 -0.770  9.171  1.000 42.130  ? 1361 LEU AAA HD23 1 
ATOM   1624 N N    . LYS A 1 101 ? -20.994 2.210   5.310  1.000 40.650  ? 1362 LYS AAA N    1 
ATOM   1625 C CA   . LYS A 1 101 ? -19.895 2.890   4.581  1.000 39.370  ? 1362 LYS AAA CA   1 
ATOM   1626 C C    . LYS A 1 101 ? -19.165 3.832   5.541  1.000 40.680  ? 1362 LYS AAA C    1 
ATOM   1627 O O    . LYS A 1 101 ? -17.952 3.816   5.559  1.000 45.240  ? 1362 LYS AAA O    1 
ATOM   1628 C CB   . LYS A 1 101 ? -20.478 3.702   3.419  1.000 43.730  ? 1362 LYS AAA CB   1 
ATOM   1629 C CG   . LYS A 1 101 ? -19.491 4.504   2.582  1.000 43.640  ? 1362 LYS AAA CG   1 
ATOM   1630 C CD   . LYS A 1 101 ? -20.143 5.183   1.388  1.000 46.920  ? 1362 LYS AAA CD   1 
ATOM   1631 C CE   . LYS A 1 101 ? -21.072 6.302   1.818  1.000 52.840  ? 1362 LYS AAA CE   1 
ATOM   1632 N NZ   . LYS A 1 101 ? -21.641 7.002   0.648  1.000 56.650  ? 1362 LYS AAA NZ   1 
ATOM   1633 H H    . LYS A 1 101 ? -21.949 2.375   5.026  1.000 40.650  ? 1362 LYS AAA H    1 
ATOM   1634 H HA   . LYS A 1 101 ? -19.262 2.206   4.262  1.000 39.370  ? 1362 LYS AAA HA   1 
ATOM   1635 H HB2  . LYS A 1 101 ? -20.954 3.090   2.819  1.000 43.730  ? 1362 LYS AAA HB2  1 
ATOM   1636 H HB3  . LYS A 1 101 ? -21.145 4.324   3.777  1.000 43.730  ? 1362 LYS AAA HB3  1 
ATOM   1637 H HG2  . LYS A 1 101 ? -19.079 5.187   3.153  1.000 43.640  ? 1362 LYS AAA HG2  1 
ATOM   1638 H HG3  . LYS A 1 101 ? -18.788 3.899   2.262  1.000 43.640  ? 1362 LYS AAA HG3  1 
ATOM   1639 H HD2  . LYS A 1 101 ? -19.443 5.543   0.803  1.000 46.920  ? 1362 LYS AAA HD2  1 
ATOM   1640 H HD3  . LYS A 1 101 ? -20.647 4.515   0.876  1.000 46.920  ? 1362 LYS AAA HD3  1 
ATOM   1641 H HE2  . LYS A 1 101 ? -21.797 5.935   2.358  1.000 52.840  ? 1362 LYS AAA HE2  1 
ATOM   1642 H HE3  . LYS A 1 101 ? -20.581 6.941   2.369  1.000 52.840  ? 1362 LYS AAA HE3  1 
ATOM   1643 H HZ1  . LYS A 1 101 ? -20.973 7.357   0.148  1.000 56.650  ? 1362 LYS AAA HZ1  1 
ATOM   1644 H HZ2  . LYS A 1 101 ? -22.195 7.664   0.926  1.000 56.650  ? 1362 LYS AAA HZ2  1 
ATOM   1645 H HZ3  . LYS A 1 101 ? -22.112 6.417   0.140  1.000 56.650  ? 1362 LYS AAA HZ3  1 
ATOM   1646 N N    . TYR A 1 102 ? -19.901 4.672   6.261  1.000 36.160  ? 1363 TYR AAA N    1 
ATOM   1647 C CA   . TYR A 1 102 ? -19.357 5.552   7.312  1.000 38.300  ? 1363 TYR AAA CA   1 
ATOM   1648 C C    . TYR A 1 102 ? -18.516 4.751   8.319  1.000 41.620  ? 1363 TYR AAA C    1 
ATOM   1649 O O    . TYR A 1 102 ? -17.481 5.246   8.791  1.000 45.850  ? 1363 TYR AAA O    1 
ATOM   1650 C CB   . TYR A 1 102 ? -20.482 6.266   8.062  1.000 37.330  ? 1363 TYR AAA CB   1 
ATOM   1651 C CG   . TYR A 1 102 ? -19.947 7.196   9.117  1.000 41.120  ? 1363 TYR AAA CG   1 
ATOM   1652 C CD1  . TYR A 1 102 ? -19.479 8.439   8.760  1.000 43.670  ? 1363 TYR AAA CD1  1 
ATOM   1653 C CD2  . TYR A 1 102 ? -19.863 6.818   10.449 1.000 43.440  ? 1363 TYR AAA CD2  1 
ATOM   1654 C CE1  . TYR A 1 102 ? -18.971 9.310   9.703  1.000 47.840  ? 1363 TYR AAA CE1  1 
ATOM   1655 C CE2  . TYR A 1 102 ? -19.349 7.665   11.410 1.000 43.780  ? 1363 TYR AAA CE2  1 
ATOM   1656 C CZ   . TYR A 1 102 ? -18.893 8.909   11.023 1.000 49.170  ? 1363 TYR AAA CZ   1 
ATOM   1657 O OH   . TYR A 1 102 ? -18.357 9.780   11.902 1.000 46.250  ? 1363 TYR AAA OH   1 
ATOM   1658 H H    . TYR A 1 102 ? -20.891 4.696   6.063  1.000 36.160  ? 1363 TYR AAA H    1 
ATOM   1659 H HA   . TYR A 1 102 ? -18.762 6.221   6.887  1.000 38.300  ? 1363 TYR AAA HA   1 
ATOM   1660 H HB2  . TYR A 1 102 ? -21.022 6.762   7.412  1.000 37.330  ? 1363 TYR AAA HB2  1 
ATOM   1661 H HB3  . TYR A 1 102 ? -21.063 5.589   8.467  1.000 37.330  ? 1363 TYR AAA HB3  1 
ATOM   1662 H HD1  . TYR A 1 102 ? -19.498 8.697   7.853  1.000 43.670  ? 1363 TYR AAA HD1  1 
ATOM   1663 H HD2  . TYR A 1 102 ? -20.164 5.962   10.704 1.000 43.440  ? 1363 TYR AAA HD2  1 
ATOM   1664 H HE1  . TYR A 1 102 ? -18.654 10.159  9.442  1.000 47.840  ? 1363 TYR AAA HE1  1 
ATOM   1665 H HE2  . TYR A 1 102 ? -19.291 7.402   12.314 1.000 43.780  ? 1363 TYR AAA HE2  1 
ATOM   1666 H HH   . TYR A 1 102 ? -18.816 10.505  11.915 0.000 46.250  ? 1363 TYR AAA HH   1 
ATOM   1667 N N    . THR A 1 103 ? -18.991 3.589   8.749  1.000 41.720  ? 1364 THR AAA N    1 
ATOM   1668 C CA   . THR A 1 103 ? -18.307 2.811   9.805  1.000 40.580  ? 1364 THR AAA CA   1 
ATOM   1669 C C    . THR A 1 103 ? -17.008 2.296   9.190  1.000 42.360  ? 1364 THR AAA C    1 
ATOM   1670 O O    . THR A 1 103 ? -15.944 2.415   9.836  1.000 42.850  ? 1364 THR AAA O    1 
ATOM   1671 C CB   . THR A 1 103 ? -19.232 1.722   10.354 1.000 42.380  ? 1364 THR AAA CB   1 
ATOM   1672 O OG1  . THR A 1 103 ? -20.302 2.403   11.022 1.000 46.440  ? 1364 THR AAA OG1  1 
ATOM   1673 C CG2  . THR A 1 103 ? -18.519 0.772   11.287 1.000 42.780  ? 1364 THR AAA CG2  1 
ATOM   1674 H H    . THR A 1 103 ? -19.842 3.227   8.344  1.000 41.720  ? 1364 THR AAA H    1 
ATOM   1675 H HA   . THR A 1 103 ? -18.107 3.421   10.552 1.000 40.580  ? 1364 THR AAA HA   1 
ATOM   1676 H HB   . THR A 1 103 ? -19.595 1.211   9.592  1.000 42.380  ? 1364 THR AAA HB   1 
ATOM   1677 H HG1  . THR A 1 103 ? -20.843 1.835   11.344 0.000 46.440  ? 1364 THR AAA HG1  1 
ATOM   1678 H HG21 . THR A 1 103 ? -17.791 0.333   10.812 1.000 42.780  ? 1364 THR AAA HG21 1 
ATOM   1679 H HG22 . THR A 1 103 ? -19.145 0.099   11.609 1.000 42.780  ? 1364 THR AAA HG22 1 
ATOM   1680 H HG23 . THR A 1 103 ? -18.159 1.267   12.044 1.000 42.780  ? 1364 THR AAA HG23 1 
ATOM   1681 N N    . LEU A 1 104 ? -17.080 1.811   7.949  1.000 38.840  ? 1365 LEU AAA N    1 
ATOM   1682 C CA   . LEU A 1 104 ? -15.902 1.242   7.226  1.000 42.180  ? 1365 LEU AAA CA   1 
ATOM   1683 C C    . LEU A 1 104 ? -14.825 2.305   6.963  1.000 44.230  ? 1365 LEU AAA C    1 
ATOM   1684 O O    . LEU A 1 104 ? -13.647 2.016   7.225  1.000 44.250  ? 1365 LEU AAA O    1 
ATOM   1685 C CB   . LEU A 1 104 ? -16.362 0.661   5.893  1.000 44.390  ? 1365 LEU AAA CB   1 
ATOM   1686 C CG   . LEU A 1 104 ? -15.244 0.129   5.006  1.000 45.040  ? 1365 LEU AAA CG   1 
ATOM   1687 C CD1  . LEU A 1 104 ? -14.460 -0.972  5.708  1.000 46.490  ? 1365 LEU AAA CD1  1 
ATOM   1688 C CD2  . LEU A 1 104 ? -15.835 -0.385  3.701  1.000 47.270  ? 1365 LEU AAA CD2  1 
ATOM   1689 H H    . LEU A 1 104 ? -17.977 1.835   7.486  1.000 38.840  ? 1365 LEU AAA H    1 
ATOM   1690 H HA   . LEU A 1 104 ? -15.498 0.542   7.789  1.000 42.180  ? 1365 LEU AAA HA   1 
ATOM   1691 H HB2  . LEU A 1 104 ? -16.992 -0.065  6.075  1.000 44.390  ? 1365 LEU AAA HB2  1 
ATOM   1692 H HB3  . LEU A 1 104 ? -16.847 1.356   5.405  1.000 44.390  ? 1365 LEU AAA HB3  1 
ATOM   1693 H HG   . LEU A 1 104 ? -14.630 0.878   4.804  1.000 45.040  ? 1365 LEU AAA HG   1 
ATOM   1694 H HD11 . LEU A 1 104 ? -14.067 -0.620  6.526  1.000 46.490  ? 1365 LEU AAA HD11 1 
ATOM   1695 H HD12 . LEU A 1 104 ? -13.754 -1.293  5.120  1.000 46.490  ? 1365 LEU AAA HD12 1 
ATOM   1696 H HD13 . LEU A 1 104 ? -15.058 -1.707  5.927  1.000 46.490  ? 1365 LEU AAA HD13 1 
ATOM   1697 H HD21 . LEU A 1 104 ? -16.468 -1.099  3.890  1.000 47.270  ? 1365 LEU AAA HD21 1 
ATOM   1698 H HD22 . LEU A 1 104 ? -15.122 -0.724  3.133  1.000 47.270  ? 1365 LEU AAA HD22 1 
ATOM   1699 H HD23 . LEU A 1 104 ? -16.294 0.341   3.244  1.000 47.270  ? 1365 LEU AAA HD23 1 
ATOM   1700 N N    . PHE A 1 105 ? -15.211 3.471   6.422  1.000 41.920  ? 1366 PHE AAA N    1 
ATOM   1701 C CA   . PHE A 1 105 ? -14.253 4.500   5.937  1.000 44.130  ? 1366 PHE AAA CA   1 
ATOM   1702 C C    . PHE A 1 105 ? -13.990 5.543   7.019  1.000 45.770  ? 1366 PHE AAA C    1 
ATOM   1703 O O    . PHE A 1 105 ? -12.937 6.109   6.955  1.000 46.590  ? 1366 PHE AAA O    1 
ATOM   1704 C CB   . PHE A 1 105 ? -14.714 5.180   4.641  1.000 43.960  ? 1366 PHE AAA CB   1 
ATOM   1705 C CG   . PHE A 1 105 ? -14.734 4.272   3.438  1.000 40.540  ? 1366 PHE AAA CG   1 
ATOM   1706 C CD1  . PHE A 1 105 ? -13.574 3.996   2.739  1.000 43.460  ? 1366 PHE AAA CD1  1 
ATOM   1707 C CD2  . PHE A 1 105 ? -15.914 3.677   3.015  1.000 37.900  ? 1366 PHE AAA CD2  1 
ATOM   1708 C CE1  . PHE A 1 105 ? -13.601 3.159   1.627  1.000 48.520  ? 1366 PHE AAA CE1  1 
ATOM   1709 C CE2  . PHE A 1 105 ? -15.936 2.816   1.928  1.000 40.380  ? 1366 PHE AAA CE2  1 
ATOM   1710 C CZ   . PHE A 1 105 ? -14.785 2.578   1.221  1.000 45.000  ? 1366 PHE AAA CZ   1 
ATOM   1711 H H    . PHE A 1 105 ? -16.203 3.647   6.346  1.000 41.920  ? 1366 PHE AAA H    1 
ATOM   1712 H HA   . PHE A 1 105 ? -13.392 4.056   5.727  1.000 44.130  ? 1366 PHE AAA HA   1 
ATOM   1713 H HB2  . PHE A 1 105 ? -15.613 5.543   4.784  1.000 43.960  ? 1366 PHE AAA HB2  1 
ATOM   1714 H HB3  . PHE A 1 105 ? -14.120 5.938   4.461  1.000 43.960  ? 1366 PHE AAA HB3  1 
ATOM   1715 H HD1  . PHE A 1 105 ? -12.759 4.381   3.018  1.000 43.460  ? 1366 PHE AAA HD1  1 
ATOM   1716 H HD2  . PHE A 1 105 ? -16.714 3.866   3.480  1.000 37.900  ? 1366 PHE AAA HD2  1 
ATOM   1717 H HE1  . PHE A 1 105 ? -12.803 2.977   1.157  1.000 48.520  ? 1366 PHE AAA HE1  1 
ATOM   1718 H HE2  . PHE A 1 105 ? -16.747 2.420   1.653  1.000 40.380  ? 1366 PHE AAA HE2  1 
ATOM   1719 H HZ   . PHE A 1 105 ? -14.798 2.011   0.466  1.000 45.000  ? 1366 PHE AAA HZ   1 
ATOM   1720 N N    . GLN A 1 106 ? -14.903 5.804   7.946  1.000 47.010  ? 1367 GLN AAA N    1 
ATOM   1721 C CA   . GLN A 1 106 ? -14.705 6.903   8.923  1.000 53.690  ? 1367 GLN AAA CA   1 
ATOM   1722 C C    . GLN A 1 106 ? -14.344 6.337   10.298 1.000 53.850  ? 1367 GLN AAA C    1 
ATOM   1723 O O    . GLN A 1 106 ? -13.459 6.906   10.896 1.000 63.760  ? 1367 GLN AAA O    1 
ATOM   1724 C CB   . GLN A 1 106 ? -15.911 7.843   8.997  1.000 56.340  ? 1367 GLN AAA CB   1 
ATOM   1725 C CG   . GLN A 1 106 ? -16.145 8.616   7.701  1.000 57.770  ? 1367 GLN AAA CG   1 
ATOM   1726 C CD   . GLN A 1 106 ? -14.922 9.288   7.106  1.000 55.570  ? 1367 GLN AAA CD   1 
ATOM   1727 O OE1  . GLN A 1 106 ? -14.197 10.005  7.786  1.000 46.240  ? 1367 GLN AAA OE1  1 
ATOM   1728 N NE2  . GLN A 1 106 ? -14.701 9.088   5.811  1.000 46.520  ? 1367 GLN AAA NE2  1 
ATOM   1729 H H    . GLN A 1 106 ? -15.746 5.250   7.992  1.000 47.010  ? 1367 GLN AAA H    1 
ATOM   1730 H HA   . GLN A 1 106 ? -13.957 7.464   8.614  1.000 53.690  ? 1367 GLN AAA HA   1 
ATOM   1731 H HB2  . GLN A 1 106 ? -16.707 7.312   9.208  1.000 56.340  ? 1367 GLN AAA HB2  1 
ATOM   1732 H HB3  . GLN A 1 106 ? -15.769 8.475   9.732  1.000 56.340  ? 1367 GLN AAA HB3  1 
ATOM   1733 H HG2  . GLN A 1 106 ? -16.501 8.005   7.021  1.000 57.770  ? 1367 GLN AAA HG2  1 
ATOM   1734 H HG3  . GLN A 1 106 ? -16.814 9.316   7.859  1.000 57.770  ? 1367 GLN AAA HG3  1 
ATOM   1735 H HE21 . GLN A 1 106 ? -14.001 9.459   5.419  0.000 46.520  ? 1367 GLN AAA HE21 1 
ATOM   1736 H HE22 . GLN A 1 106 ? -15.254 8.584   5.341  0.000 46.520  ? 1367 GLN AAA HE22 1 
ATOM   1737 N N    . ILE A 1 107 ? -14.960 5.258   10.772 1.000 48.410  ? 1368 ILE AAA N    1 
ATOM   1738 C CA   . ILE A 1 107 ? -14.640 4.734   12.126 1.000 43.940  ? 1368 ILE AAA CA   1 
ATOM   1739 C C    . ILE A 1 107 ? -13.474 3.760   11.984 1.000 45.730  ? 1368 ILE AAA C    1 
ATOM   1740 O O    . ILE A 1 107 ? -12.486 3.994   12.647 1.000 43.530  ? 1368 ILE AAA O    1 
ATOM   1741 C CB   . ILE A 1 107 ? -15.873 4.149   12.828 1.000 43.390  ? 1368 ILE AAA CB   1 
ATOM   1742 C CG1  . ILE A 1 107 ? -16.893 5.250   13.119 1.000 39.880  ? 1368 ILE AAA CG1  1 
ATOM   1743 C CG2  . ILE A 1 107 ? -15.485 3.396   14.099 1.000 44.010  ? 1368 ILE AAA CG2  1 
ATOM   1744 C CD1  . ILE A 1 107 ? -18.244 4.739   13.586 1.000 41.970  ? 1368 ILE AAA CD1  1 
ATOM   1745 H H    . ILE A 1 107 ? -15.654 4.784   10.212 1.000 48.410  ? 1368 ILE AAA H    1 
ATOM   1746 H HA   . ILE A 1 107 ? -14.363 5.481   12.687 1.000 43.940  ? 1368 ILE AAA HA   1 
ATOM   1747 H HB   . ILE A 1 107 ? -16.282 3.494   12.211 1.000 43.390  ? 1368 ILE AAA HB   1 
ATOM   1748 H HG12 . ILE A 1 107 ? -16.527 5.843   13.809 1.000 39.880  ? 1368 ILE AAA HG12 1 
ATOM   1749 H HG13 . ILE A 1 107 ? -17.024 5.781   12.304 1.000 39.880  ? 1368 ILE AAA HG13 1 
ATOM   1750 H HG21 . ILE A 1 107 ? -14.885 2.663   13.875 1.000 44.010  ? 1368 ILE AAA HG21 1 
ATOM   1751 H HG22 . ILE A 1 107 ? -16.283 3.034   14.522 1.000 44.010  ? 1368 ILE AAA HG22 1 
ATOM   1752 H HG23 . ILE A 1 107 ? -15.039 4.002   14.716 1.000 44.010  ? 1368 ILE AAA HG23 1 
ATOM   1753 H HD11 . ILE A 1 107 ? -18.631 4.167   12.901 1.000 41.970  ? 1368 ILE AAA HD11 1 
ATOM   1754 H HD12 . ILE A 1 107 ? -18.838 5.492   13.751 1.000 41.970  ? 1368 ILE AAA HD12 1 
ATOM   1755 H HD13 . ILE A 1 107 ? -18.133 4.229   14.407 1.000 41.970  ? 1368 ILE AAA HD13 1 
ATOM   1756 N N    . PHE A 1 108 ? -13.551 2.754   11.120 1.000 46.040  ? 1369 PHE AAA N    1 
ATOM   1757 C CA   . PHE A 1 108 ? -12.536 1.670   11.042 1.000 48.720  ? 1369 PHE AAA CA   1 
ATOM   1758 C C    . PHE A 1 108 ? -11.638 1.803   9.800  1.000 54.750  ? 1369 PHE AAA C    1 
ATOM   1759 O O    . PHE A 1 108 ? -11.177 0.740   9.277  1.000 51.960  ? 1369 PHE AAA O    1 
ATOM   1760 C CB   . PHE A 1 108 ? -13.240 0.315   11.076 1.000 50.110  ? 1369 PHE AAA CB   1 
ATOM   1761 C CG   . PHE A 1 108 ? -13.861 -0.021  12.407 1.000 53.280  ? 1369 PHE AAA CG   1 
ATOM   1762 C CD1  . PHE A 1 108 ? -13.095 -0.027  13.571 1.000 52.500  ? 1369 PHE AAA CD1  1 
ATOM   1763 C CD2  . PHE A 1 108 ? -15.208 -0.342  12.499 1.000 54.860  ? 1369 PHE AAA CD2  1 
ATOM   1764 C CE1  . PHE A 1 108 ? -13.670 -0.345  14.797 1.000 54.510  ? 1369 PHE AAA CE1  1 
ATOM   1765 C CE2  . PHE A 1 108 ? -15.777 -0.677  13.721 1.000 54.810  ? 1369 PHE AAA CE2  1 
ATOM   1766 C CZ   . PHE A 1 108 ? -15.006 -0.681  14.869 1.000 56.190  ? 1369 PHE AAA CZ   1 
ATOM   1767 H H    . PHE A 1 108 ? -14.341 2.735   10.491 1.000 46.040  ? 1369 PHE AAA H    1 
ATOM   1768 H HA   . PHE A 1 108 ? -11.947 1.731   11.836 1.000 48.720  ? 1369 PHE AAA HA   1 
ATOM   1769 H HB2  . PHE A 1 108 ? -13.935 0.309   10.385 1.000 50.110  ? 1369 PHE AAA HB2  1 
ATOM   1770 H HB3  . PHE A 1 108 ? -12.589 -0.378  10.839 1.000 50.110  ? 1369 PHE AAA HB3  1 
ATOM   1771 H HD1  . PHE A 1 108 ? -12.176 0.182   13.525 1.000 52.500  ? 1369 PHE AAA HD1  1 
ATOM   1772 H HD2  . PHE A 1 108 ? -15.742 -0.332  11.720 1.000 54.860  ? 1369 PHE AAA HD2  1 
ATOM   1773 H HE1  . PHE A 1 108 ? -13.140 -0.345  15.578 1.000 54.510  ? 1369 PHE AAA HE1  1 
ATOM   1774 H HE2  . PHE A 1 108 ? -16.691 -0.907  13.768 1.000 54.810  ? 1369 PHE AAA HE2  1 
ATOM   1775 H HZ   . PHE A 1 108 ? -15.394 -0.896  15.702 1.000 56.190  ? 1369 PHE AAA HZ   1 
ATOM   1776 N N    . SER A 1 109 ? -11.349 3.042   9.367  1.000 58.550  ? 1370 SER AAA N    1 
ATOM   1777 C CA   . SER A 1 109 ? -10.398 3.357   8.258  1.000 68.810  ? 1370 SER AAA CA   1 
ATOM   1778 C C    . SER A 1 109 ? -9.039  2.735   8.547  1.000 79.360  ? 1370 SER AAA C    1 
ATOM   1779 O O    . SER A 1 109 ? -8.393  2.318   7.593  1.000 84.110  ? 1370 SER AAA O    1 
ATOM   1780 C CB   . SER A 1 109 ? -10.206 4.825   8.067  1.000 66.970  ? 1370 SER AAA CB   1 
ATOM   1781 O OG   . SER A 1 109 ? -10.231 5.473   9.323  1.000 67.730  ? 1370 SER AAA OG   1 
ATOM   1782 H H    . SER A 1 109 ? -11.821 3.799   9.841  1.000 58.550  ? 1370 SER AAA H    1 
ATOM   1783 H HA   . SER A 1 109 ? -10.754 2.951   7.422  1.000 68.810  ? 1370 SER AAA HA   1 
ATOM   1784 H HB2  . SER A 1 109 ? -9.343  4.985   7.622  1.000 66.970  ? 1370 SER AAA HB2  1 
ATOM   1785 H HB3  . SER A 1 109 ? -10.924 5.175   7.492  1.000 66.970  ? 1370 SER AAA HB3  1 
ATOM   1786 H HG   . SER A 1 109 ? -10.121 6.303   9.200  0.000 67.730  ? 1370 SER AAA HG   1 
ATOM   1787 N N    . LYS A 1 110 ? -8.623  2.721   9.815  1.000 94.150  ? 1371 LYS AAA N    1 
ATOM   1788 C CA   . LYS A 1 110 ? -7.385  2.036   10.261 1.000 92.040  ? 1371 LYS AAA CA   1 
ATOM   1789 C C    . LYS A 1 110 ? -7.633  1.363   11.616 1.000 88.230  ? 1371 LYS AAA C    1 
ATOM   1790 O O    . LYS A 1 110 ? -8.494  1.839   12.382 1.000 82.830  ? 1371 LYS AAA O    1 
ATOM   1791 C CB   . LYS A 1 110 ? -6.224  3.040   10.251 1.000 93.410  ? 1371 LYS AAA CB   1 
ATOM   1792 C CG   . LYS A 1 110 ? -4.854  2.465   9.883  1.000 101.040 ? 1371 LYS AAA CG   1 
ATOM   1793 C CD   . LYS A 1 110 ? -4.823  1.436   8.733  1.000 95.380  ? 1371 LYS AAA CD   1 
ATOM   1794 C CE   . LYS A 1 110 ? -4.124  0.142   9.108  1.000 86.320  ? 1371 LYS AAA CE   1 
ATOM   1795 N NZ   . LYS A 1 110 ? -4.889  -1.053  8.688  1.000 75.450  ? 1371 LYS AAA NZ   1 
ATOM   1796 H H    . LYS A 1 110 ? -9.190  3.206   10.496 1.000 94.150  ? 1371 LYS AAA H    1 
ATOM   1797 H HA   . LYS A 1 110 ? -7.157  1.342   9.600  1.000 92.040  ? 1371 LYS AAA HA   1 
ATOM   1798 H HB2  . LYS A 1 110 ? -6.439  3.759   9.620  1.000 93.410  ? 1371 LYS AAA HB2  1 
ATOM   1799 H HB3  . LYS A 1 110 ? -6.160  3.451   11.138 1.000 93.410  ? 1371 LYS AAA HB3  1 
ATOM   1800 H HG2  . LYS A 1 110 ? -4.263  3.204   9.625  1.000 101.040 ? 1371 LYS AAA HG2  1 
ATOM   1801 H HG3  . LYS A 1 110 ? -4.477  2.025   10.674 1.000 101.040 ? 1371 LYS AAA HG3  1 
ATOM   1802 H HD2  . LYS A 1 110 ? -5.743  1.232   8.461  1.000 95.380  ? 1371 LYS AAA HD2  1 
ATOM   1803 H HD3  . LYS A 1 110 ? -4.364  1.832   7.962  1.000 95.380  ? 1371 LYS AAA HD3  1 
ATOM   1804 H HE2  . LYS A 1 110 ? -3.243  0.113   8.688  1.000 86.320  ? 1371 LYS AAA HE2  1 
ATOM   1805 H HE3  . LYS A 1 110 ? -3.997  0.107   10.075 1.000 86.320  ? 1371 LYS AAA HE3  1 
ATOM   1806 H HZ1  . LYS A 1 110 ? -5.705  -1.050  9.085  1.000 75.450  ? 1371 LYS AAA HZ1  1 
ATOM   1807 H HZ2  . LYS A 1 110 ? -4.440  -1.804  8.926  1.000 75.450  ? 1371 LYS AAA HZ2  1 
ATOM   1808 H HZ3  . LYS A 1 110 ? -4.998  -1.047  7.788  1.000 75.450  ? 1371 LYS AAA HZ3  1 
ATOM   1809 N N    . ILE A 1 111 ? -6.903  0.277   11.876 1.000 87.550  ? 1372 ILE AAA N    1 
ATOM   1810 C CA   . ILE A 1 111 ? -7.011  -0.570  13.103 1.000 79.480  ? 1372 ILE AAA CA   1 
ATOM   1811 C C    . ILE A 1 111 ? -5.921  -0.169  14.106 1.000 72.080  ? 1372 ILE AAA C    1 
ATOM   1812 O O    . ILE A 1 111 ? -4.812  -0.732  14.011 1.000 64.130  ? 1372 ILE AAA O    1 
ATOM   1813 C CB   . ILE A 1 111 ? -6.927  -2.039  12.661 1.000 71.780  ? 1372 ILE AAA CB   1 
ATOM   1814 C CG1  . ILE A 1 111 ? -8.004  -2.320  11.604 1.000 79.180  ? 1372 ILE AAA CG1  1 
ATOM   1815 C CG2  . ILE A 1 111 ? -7.018  -2.977  13.851 1.000 71.640  ? 1372 ILE AAA CG2  1 
ATOM   1816 C CD1  . ILE A 1 111 ? -9.408  -1.759  11.928 1.000 70.270  ? 1372 ILE AAA CD1  1 
ATOM   1817 H H    . ILE A 1 111 ? -6.229  0.031   11.166 1.000 87.550  ? 1372 ILE AAA H    1 
ATOM   1818 H HA   . ILE A 1 111 ? -7.878  -0.404  13.516 1.000 79.480  ? 1372 ILE AAA HA   1 
ATOM   1819 H HB   . ILE A 1 111 ? -6.039  -2.173  12.246 1.000 71.780  ? 1372 ILE AAA HB   1 
ATOM   1820 H HG12 . ILE A 1 111 ? -7.713  -1.937  10.749 1.000 79.180  ? 1372 ILE AAA HG12 1 
ATOM   1821 H HG13 . ILE A 1 111 ? -8.084  -3.291  11.487 1.000 79.180  ? 1372 ILE AAA HG13 1 
ATOM   1822 H HG21 . ILE A 1 111 ? -6.284  -2.799  14.465 1.000 71.640  ? 1372 ILE AAA HG21 1 
ATOM   1823 H HG22 . ILE A 1 111 ? -6.960  -3.899  13.546 1.000 71.640  ? 1372 ILE AAA HG22 1 
ATOM   1824 H HG23 . ILE A 1 111 ? -7.865  -2.841  14.311 1.000 71.640  ? 1372 ILE AAA HG23 1 
ATOM   1825 H HD11 . ILE A 1 111 ? -9.730  -2.148  12.760 1.000 70.270  ? 1372 ILE AAA HD11 1 
ATOM   1826 H HD12 . ILE A 1 111 ? -10.023 -1.983  11.208 1.000 70.270  ? 1372 ILE AAA HD12 1 
ATOM   1827 H HD13 . ILE A 1 111 ? -9.359  -0.792  12.021 1.000 70.270  ? 1372 ILE AAA HD13 1 
ATOM   1828 N N    . ASP A 1 112 ? -6.222  0.803   14.985 1.000 68.200  ? 1373 ASP AAA N    1 
ATOM   1829 C CA   . ASP A 1 112 ? -5.367  1.215   16.132 1.000 69.890  ? 1373 ASP AAA CA   1 
ATOM   1830 C C    . ASP A 1 112 ? -5.138  0.029   17.068 1.000 65.580  ? 1373 ASP AAA C    1 
ATOM   1831 O O    . ASP A 1 112 ? -4.082  -0.030  17.695 1.000 73.760  ? 1373 ASP AAA O    1 
ATOM   1832 C CB   . ASP A 1 112 ? -6.025  2.208   17.092 1.000 68.860  ? 1373 ASP AAA CB   1 
ATOM   1833 C CG   . ASP A 1 112 ? -6.367  3.571   16.532 1.000 68.230  ? 1373 ASP AAA CG   1 
ATOM   1834 O OD1  . ASP A 1 112 ? -6.361  3.709   15.318 1.000 64.300  ? 1373 ASP AAA OD1  1 
ATOM   1835 O OD2  . ASP A 1 112 ? -6.637  4.480   17.350 1.000 72.890  ? 1373 ASP AAA OD2  1 
ATOM   1836 H H    . ASP A 1 112 ? -7.102  1.274   14.833 1.000 68.200  ? 1373 ASP AAA H    1 
ATOM   1837 H HA   . ASP A 1 112 ? -4.493  1.508   15.781 1.000 69.890  ? 1373 ASP AAA HA   1 
ATOM   1838 H HB2  . ASP A 1 112 ? -6.869  1.823   17.406 1.000 68.860  ? 1373 ASP AAA HB2  1 
ATOM   1839 H HB3  . ASP A 1 112 ? -5.415  2.367   17.841 1.000 68.860  ? 1373 ASP AAA HB3  1 
ATOM   1840 N N    . ARG A 1 113 ? -6.159  -0.801  17.241 1.000 55.580  ? 1374 ARG AAA N    1 
ATOM   1841 C CA   . ARG A 1 113 ? -6.216  -1.776  18.342 1.000 51.200  ? 1374 ARG AAA CA   1 
ATOM   1842 C C    . ARG A 1 113 ? -6.398  -3.133  17.705 1.000 49.730  ? 1374 ARG AAA C    1 
ATOM   1843 O O    . ARG A 1 113 ? -7.469  -3.716  17.731 1.000 62.660  ? 1374 ARG AAA O    1 
ATOM   1844 C CB   . ARG A 1 113 ? -7.329  -1.439  19.335 1.000 52.170  ? 1374 ARG AAA CB   1 
ATOM   1845 C CG   . ARG A 1 113 ? -6.987  -0.344  20.329 1.000 50.390  ? 1374 ARG AAA CG   1 
ATOM   1846 C CD   . ARG A 1 113 ? -8.140  -0.070  21.270 1.000 48.810  ? 1374 ARG AAA CD   1 
ATOM   1847 N NE   . ARG A 1 113 ? -8.131  -1.001  22.383 1.000 54.450  ? 1374 ARG AAA NE   1 
ATOM   1848 C CZ   . ARG A 1 113 ? -9.176  -1.304  23.148 1.000 56.690  ? 1374 ARG AAA CZ   1 
ATOM   1849 N NH1  . ARG A 1 113 ? -10.371 -0.794  22.907 1.000 57.310  ? 1374 ARG AAA NH1  1 
ATOM   1850 N NH2  . ARG A 1 113 ? -9.031  -2.153  24.149 1.000 61.450  ? 1374 ARG AAA NH2  1 
ATOM   1851 H H    . ARG A 1 113 ? -6.925  -0.754  16.584 1.000 55.580  ? 1374 ARG AAA H    1 
ATOM   1852 H HA   . ARG A 1 113 ? -5.362  -1.744  18.832 1.000 51.200  ? 1374 ARG AAA HA   1 
ATOM   1853 H HB2  . ARG A 1 113 ? -8.123  -1.163  18.831 1.000 52.170  ? 1374 ARG AAA HB2  1 
ATOM   1854 H HB3  . ARG A 1 113 ? -7.557  -2.250  19.835 1.000 52.170  ? 1374 ARG AAA HB3  1 
ATOM   1855 H HG2  . ARG A 1 113 ? -6.199  -0.613  20.848 1.000 50.390  ? 1374 ARG AAA HG2  1 
ATOM   1856 H HG3  . ARG A 1 113 ? -6.762  0.477   19.841 1.000 50.390  ? 1374 ARG AAA HG3  1 
ATOM   1857 H HD2  . ARG A 1 113 ? -8.073  0.850   21.603 1.000 48.810  ? 1374 ARG AAA HD2  1 
ATOM   1858 H HD3  . ARG A 1 113 ? -8.984  -0.146  20.776 1.000 48.810  ? 1374 ARG AAA HD3  1 
ATOM   1859 H HE   . ARG A 1 113 ? -7.380  -1.401  22.574 1.000 54.450  ? 1374 ARG AAA HE   1 
ATOM   1860 H HH11 . ARG A 1 113 ? -10.484 -0.244  22.231 1.000 57.310  ? 1374 ARG AAA HH11 1 
ATOM   1861 H HH12 . ARG A 1 113 ? -11.050 -1.006  23.424 1.000 57.310  ? 1374 ARG AAA HH12 1 
ATOM   1862 H HH21 . ARG A 1 113 ? -8.243  -2.515  24.306 1.000 61.450  ? 1374 ARG AAA HH21 1 
ATOM   1863 H HH22 . ARG A 1 113 ? -9.722  -2.355  24.657 1.000 61.450  ? 1374 ARG AAA HH22 1 
ATOM   1864 N N    . PRO A 1 114 ? -5.349  -3.680  17.083 1.000 53.880  ? 1375 PRO AAA N    1 
ATOM   1865 C CA   . PRO A 1 114 ? -5.430  -5.060  16.630 1.000 51.150  ? 1375 PRO AAA CA   1 
ATOM   1866 C C    . PRO A 1 114 ? -5.574  -6.008  17.830 1.000 49.880  ? 1375 PRO AAA C    1 
ATOM   1867 O O    . PRO A 1 114 ? -6.064  -7.088  17.614 1.000 59.290  ? 1375 PRO AAA O    1 
ATOM   1868 C CB   . PRO A 1 114 ? -4.149  -5.266  15.816 1.000 52.860  ? 1375 PRO AAA CB   1 
ATOM   1869 C CG   . PRO A 1 114 ? -3.210  -4.144  16.278 1.000 55.440  ? 1375 PRO AAA CG   1 
ATOM   1870 C CD   . PRO A 1 114 ? -4.080  -3.010  16.767 1.000 54.030  ? 1375 PRO AAA CD   1 
ATOM   1871 H HA   . PRO A 1 114 ? -6.200  -5.158  16.015 1.000 51.150  ? 1375 PRO AAA HA   1 
ATOM   1872 H HB2  . PRO A 1 114 ? -3.759  -6.148  15.991 1.000 52.860  ? 1375 PRO AAA HB2  1 
ATOM   1873 H HB3  . PRO A 1 114 ? -4.329  -5.203  14.855 1.000 52.860  ? 1375 PRO AAA HB3  1 
ATOM   1874 H HG2  . PRO A 1 114 ? -2.625  -4.454  17.001 1.000 55.440  ? 1375 PRO AAA HG2  1 
ATOM   1875 H HG3  . PRO A 1 114 ? -2.643  -3.837  15.540 1.000 55.440  ? 1375 PRO AAA HG3  1 
ATOM   1876 H HD2  . PRO A 1 114 ? -3.685  -2.581  17.554 1.000 54.030  ? 1375 PRO AAA HD2  1 
ATOM   1877 H HD3  . PRO A 1 114 ? -4.188  -2.328  16.072 1.000 54.030  ? 1375 PRO AAA HD3  1 
ATOM   1878 N N    . GLU A 1 115 ? -5.160  -5.617  19.045 1.000 53.820  ? 1376 GLU AAA N    1 
ATOM   1879 C CA   . GLU A 1 115 ? -5.314  -6.474  20.260 1.000 55.770  ? 1376 GLU AAA CA   1 
ATOM   1880 C C    . GLU A 1 115 ? -6.809  -6.651  20.629 1.000 60.930  ? 1376 GLU AAA C    1 
ATOM   1881 O O    . GLU A 1 115 ? -7.115  -7.716  21.214 1.000 60.260  ? 1376 GLU AAA O    1 
ATOM   1882 C CB   . GLU A 1 115 ? -4.477  -5.973  21.437 1.000 49.820  ? 1376 GLU AAA CB   1 
ATOM   1883 C CG   . GLU A 1 115 ? -4.892  -4.610  21.965 1.000 55.110  ? 1376 GLU AAA CG   1 
ATOM   1884 C CD   . GLU A 1 115 ? -4.310  -3.457  21.175 1.000 58.080  ? 1376 GLU AAA CD   1 
ATOM   1885 O OE1  . GLU A 1 115 ? -3.884  -3.732  20.032 1.000 54.790  ? 1376 GLU AAA OE1  1 
ATOM   1886 O OE2  . GLU A 1 115 ? -4.242  -2.309  21.712 1.000 56.530  ? 1376 GLU AAA OE2  1 
ATOM   1887 H H    . GLU A 1 115 ? -4.729  -4.708  19.135 1.000 53.820  ? 1376 GLU AAA H    1 
ATOM   1888 H HA   . GLU A 1 115 ? -4.942  -7.365  20.063 1.000 55.770  ? 1376 GLU AAA HA   1 
ATOM   1889 H HB2  . GLU A 1 115 ? -4.546  -6.623  22.168 1.000 49.820  ? 1376 GLU AAA HB2  1 
ATOM   1890 H HB3  . GLU A 1 115 ? -3.540  -5.924  21.155 1.000 49.820  ? 1376 GLU AAA HB3  1 
ATOM   1891 H HG2  . GLU A 1 115 ? -5.871  -4.548  21.949 1.000 55.110  ? 1376 GLU AAA HG2  1 
ATOM   1892 H HG3  . GLU A 1 115 ? -4.609  -4.532  22.901 1.000 55.110  ? 1376 GLU AAA HG3  1 
ATOM   1893 N N    . ALA A 1 116 ? -7.689  -5.689  20.270 1.000 56.460  ? 1377 ALA AAA N    1 
ATOM   1894 C CA   . ALA A 1 116 ? -9.163  -5.665  20.515 1.000 51.270  ? 1377 ALA AAA CA   1 
ATOM   1895 C C    . ALA A 1 116 ? -9.978  -6.410  19.427 1.000 53.010  ? 1377 ALA AAA C    1 
ATOM   1896 O O    . ALA A 1 116 ? -9.559  -6.448  18.240 1.000 46.480  ? 1377 ALA AAA O    1 
ATOM   1897 C CB   . ALA A 1 116 ? -9.615  -4.226  20.610 1.000 46.710  ? 1377 ALA AAA CB   1 
ATOM   1898 H H    . ALA A 1 116 ? -7.258  -4.916  19.783 1.000 56.460  ? 1377 ALA AAA H    1 
ATOM   1899 H HA   . ALA A 1 116 ? -9.346  -6.121  21.370 1.000 51.270  ? 1377 ALA AAA HA   1 
ATOM   1900 H HB1  . ALA A 1 116 ? -10.571 -4.196  20.770 1.000 46.710  ? 1377 ALA AAA HB1  1 
ATOM   1901 H HB2  . ALA A 1 116 ? -9.152  -3.788  21.342 1.000 46.710  ? 1377 ALA AAA HB2  1 
ATOM   1902 H HB3  . ALA A 1 116 ? -9.412  -3.766  19.778 1.000 46.710  ? 1377 ALA AAA HB3  1 
ATOM   1903 N N    . SER A 1 117 ? -11.138 -6.972  19.790 1.000 46.210  ? 1378 SER AAA N    1 
ATOM   1904 C CA   . SER A 1 117 ? -12.232 -7.212  18.812 1.000 48.750  ? 1378 SER AAA CA   1 
ATOM   1905 C C    . SER A 1 117 ? -12.882 -5.867  18.473 1.000 44.640  ? 1378 SER AAA C    1 
ATOM   1906 O O    . SER A 1 117 ? -12.825 -4.922  19.302 1.000 41.190  ? 1378 SER AAA O    1 
ATOM   1907 C CB   . SER A 1 117 ? -13.257 -8.166  19.316 1.000 49.510  ? 1378 SER AAA CB   1 
ATOM   1908 O OG   . SER A 1 117 ? -12.680 -9.421  19.569 1.000 49.260  ? 1378 SER AAA OG   1 
ATOM   1909 H H    . SER A 1 117 ? -11.272 -7.240  20.755 1.000 46.210  ? 1378 SER AAA H    1 
ATOM   1910 H HA   . SER A 1 117 ? -11.829 -7.593  17.986 1.000 48.750  ? 1378 SER AAA HA   1 
ATOM   1911 H HB2  . SER A 1 117 ? -13.651 -7.812  20.145 1.000 49.510  ? 1378 SER AAA HB2  1 
ATOM   1912 H HB3  . SER A 1 117 ? -13.971 -8.261  18.645 1.000 49.510  ? 1378 SER AAA HB3  1 
ATOM   1913 H HG   . SER A 1 117 ? -13.283 -9.942  19.853 0.000 49.260  ? 1378 SER AAA HG   1 
ATOM   1914 N N    . ARG A 1 118 ? -13.498 -5.804  17.302 1.000 44.520  ? 1379 ARG AAA N    1 
ATOM   1915 C CA   . ARG A 1 118 ? -14.233 -4.628  16.774 1.000 44.150  ? 1379 ARG AAA CA   1 
ATOM   1916 C C    . ARG A 1 118 ? -15.667 -5.067  16.449 1.000 42.910  ? 1379 ARG AAA C    1 
ATOM   1917 O O    . ARG A 1 118 ? -15.820 -6.095  15.743 1.000 38.380  ? 1379 ARG AAA O    1 
ATOM   1918 C CB   . ARG A 1 118 ? -13.494 -4.127  15.531 1.000 47.310  ? 1379 ARG AAA CB   1 
ATOM   1919 C CG   . ARG A 1 118 ? -12.288 -3.242  15.819 1.000 51.420  ? 1379 ARG AAA CG   1 
ATOM   1920 C CD   . ARG A 1 118 ? -11.367 -3.031  14.606 1.000 54.040  ? 1379 ARG AAA CD   1 
ATOM   1921 N NE   . ARG A 1 118 ? -10.959 -4.368  14.254 1.000 60.010  ? 1379 ARG AAA NE   1 
ATOM   1922 C CZ   . ARG A 1 118 ? -10.111 -5.090  14.983 1.000 72.030  ? 1379 ARG AAA CZ   1 
ATOM   1923 N NH1  . ARG A 1 118 ? -9.483  -4.576  16.036 1.000 71.480  ? 1379 ARG AAA NH1  1 
ATOM   1924 N NH2  . ARG A 1 118 ? -9.850  -6.330  14.630 1.000 74.580  ? 1379 ARG AAA NH2  1 
ATOM   1925 H H    . ARG A 1 118 ? -13.446 -6.644  16.743 1.000 44.520  ? 1379 ARG AAA H    1 
ATOM   1926 H HA   . ARG A 1 118 ? -14.255 -3.934  17.473 1.000 44.150  ? 1379 ARG AAA HA   1 
ATOM   1927 H HB2  . ARG A 1 118 ? -13.193 -4.903  15.014 1.000 47.310  ? 1379 ARG AAA HB2  1 
ATOM   1928 H HB3  . ARG A 1 118 ? -14.124 -3.621  14.976 1.000 47.310  ? 1379 ARG AAA HB3  1 
ATOM   1929 H HG2  . ARG A 1 118 ? -12.597 -2.363  16.125 1.000 51.420  ? 1379 ARG AAA HG2  1 
ATOM   1930 H HG3  . ARG A 1 118 ? -11.757 -3.643  16.540 1.000 51.420  ? 1379 ARG AAA HG3  1 
ATOM   1931 H HD2  . ARG A 1 118 ? -11.867 -2.574  13.897 1.000 54.040  ? 1379 ARG AAA HD2  1 
ATOM   1932 H HD3  . ARG A 1 118 ? -10.621 -2.449  14.865 1.000 54.040  ? 1379 ARG AAA HD3  1 
ATOM   1933 H HE   . ARG A 1 118 ? -11.288 -4.716  13.525 1.000 60.010  ? 1379 ARG AAA HE   1 
ATOM   1934 H HH11 . ARG A 1 118 ? -9.625  -3.739  16.265 1.000 71.480  ? 1379 ARG AAA HH11 1 
ATOM   1935 H HH12 . ARG A 1 118 ? -8.928  -5.074  16.501 1.000 71.480  ? 1379 ARG AAA HH12 1 
ATOM   1936 H HH21 . ARG A 1 118 ? -10.236 -6.673  13.917 1.000 74.580  ? 1379 ARG AAA HH21 1 
ATOM   1937 H HH22 . ARG A 1 118 ? -9.290  -6.813  15.108 1.000 74.580  ? 1379 ARG AAA HH22 1 
ATOM   1938 N N    . ILE A 1 119 ? -16.689 -4.376  16.975 1.000 42.630  ? 1380 ILE AAA N    1 
ATOM   1939 C CA   . ILE A 1 119 ? -18.106 -4.798  16.764 1.000 43.150  ? 1380 ILE AAA CA   1 
ATOM   1940 C C    . ILE A 1 119 ? -18.959 -3.609  16.314 1.000 40.600  ? 1380 ILE AAA C    1 
ATOM   1941 O O    . ILE A 1 119 ? -18.930 -2.558  16.985 1.000 38.900  ? 1380 ILE AAA O    1 
ATOM   1942 C CB   . ILE A 1 119 ? -18.656 -5.518  18.009 1.000 44.260  ? 1380 ILE AAA CB   1 
ATOM   1943 C CG1  . ILE A 1 119 ? -17.823 -6.765  18.318 1.000 47.320  ? 1380 ILE AAA CG1  1 
ATOM   1944 C CG2  . ILE A 1 119 ? -20.126 -5.895  17.838 1.000 45.630  ? 1380 ILE AAA CG2  1 
ATOM   1945 C CD1  . ILE A 1 119 ? -18.314 -7.555  19.531 1.000 50.450  ? 1380 ILE AAA CD1  1 
ATOM   1946 H H    . ILE A 1 119 ? -16.498 -3.552  17.526 1.000 42.630  ? 1380 ILE AAA H    1 
ATOM   1947 H HA   . ILE A 1 119 ? -18.126 -5.463  16.053 1.000 43.150  ? 1380 ILE AAA HA   1 
ATOM   1948 H HB   . ILE A 1 119 ? -18.603 -4.883  18.766 1.000 44.260  ? 1380 ILE AAA HB   1 
ATOM   1949 H HG12 . ILE A 1 119 ? -17.835 -7.354  17.533 1.000 47.320  ? 1380 ILE AAA HG12 1 
ATOM   1950 H HG13 . ILE A 1 119 ? -16.894 -6.492  18.475 1.000 47.320  ? 1380 ILE AAA HG13 1 
ATOM   1951 H HG21 . ILE A 1 119 ? -20.655 -5.091  17.694 1.000 45.630  ? 1380 ILE AAA HG21 1 
ATOM   1952 H HG22 . ILE A 1 119 ? -20.444 -6.345  18.640 1.000 45.630  ? 1380 ILE AAA HG22 1 
ATOM   1953 H HG23 . ILE A 1 119 ? -20.225 -6.489  17.074 1.000 45.630  ? 1380 ILE AAA HG23 1 
ATOM   1954 H HD11 . ILE A 1 119 ? -18.286 -6.989  20.322 1.000 50.450  ? 1380 ILE AAA HD11 1 
ATOM   1955 H HD12 . ILE A 1 119 ? -17.742 -8.330  19.669 1.000 50.450  ? 1380 ILE AAA HD12 1 
ATOM   1956 H HD13 . ILE A 1 119 ? -19.228 -7.852  19.378 1.000 50.450  ? 1380 ILE AAA HD13 1 
ATOM   1957 N N    . ALA A 1 120 ? -19.715 -3.816  15.233 1.000 39.800  ? 1381 ALA AAA N    1 
ATOM   1958 C CA   . ALA A 1 120 ? -20.789 -2.916  14.755 1.000 47.120  ? 1381 ALA AAA CA   1 
ATOM   1959 C C    . ALA A 1 120 ? -22.123 -3.525  15.163 1.000 44.230  ? 1381 ALA AAA C    1 
ATOM   1960 O O    . ALA A 1 120 ? -22.517 -4.587  14.600 1.000 40.920  ? 1381 ALA AAA O    1 
ATOM   1961 C CB   . ALA A 1 120 ? -20.741 -2.718  13.256 1.000 50.990  ? 1381 ALA AAA CB   1 
ATOM   1962 H H    . ALA A 1 120 ? -19.517 -4.662  14.719 1.000 39.800  ? 1381 ALA AAA H    1 
ATOM   1963 H HA   . ALA A 1 120 ? -20.682 -2.039  15.193 1.000 47.120  ? 1381 ALA AAA HA   1 
ATOM   1964 H HB1  . ALA A 1 120 ? -21.458 -2.124  12.984 1.000 50.990  ? 1381 ALA AAA HB1  1 
ATOM   1965 H HB2  . ALA A 1 120 ? -19.888 -2.328  13.007 1.000 50.990  ? 1381 ALA AAA HB2  1 
ATOM   1966 H HB3  . ALA A 1 120 ? -20.846 -3.576  12.811 1.000 50.990  ? 1381 ALA AAA HB3  1 
ATOM   1967 N N    . LEU A 1 121 ? -22.775 -2.867  16.114 1.000 39.130  ? 1382 LEU AAA N    1 
ATOM   1968 C CA   . LEU A 1 121 ? -24.114 -3.265  16.592 1.000 39.080  ? 1382 LEU AAA CA   1 
ATOM   1969 C C    . LEU A 1 121 ? -25.143 -2.457  15.802 1.000 38.840  ? 1382 LEU AAA C    1 
ATOM   1970 O O    . LEU A 1 121 ? -25.419 -1.285  16.167 1.000 43.450  ? 1382 LEU AAA O    1 
ATOM   1971 C CB   . LEU A 1 121 ? -24.194 -3.017  18.102 1.000 36.510  ? 1382 LEU AAA CB   1 
ATOM   1972 C CG   . LEU A 1 121 ? -25.380 -3.686  18.775 1.000 40.380  ? 1382 LEU AAA CG   1 
ATOM   1973 C CD1  . LEU A 1 121 ? -25.298 -5.194  18.602 1.000 43.160  ? 1382 LEU AAA CD1  1 
ATOM   1974 C CD2  . LEU A 1 121 ? -25.496 -3.287  20.240 1.000 42.280  ? 1382 LEU AAA CD2  1 
ATOM   1975 H H    . LEU A 1 121 ? -22.326 -2.059  16.522 1.000 39.130  ? 1382 LEU AAA H    1 
ATOM   1976 H HA   . LEU A 1 121 ? -24.238 -4.225  16.411 1.000 39.080  ? 1382 LEU AAA HA   1 
ATOM   1977 H HB2  . LEU A 1 121 ? -23.367 -3.340  18.511 1.000 36.510  ? 1382 LEU AAA HB2  1 
ATOM   1978 H HB3  . LEU A 1 121 ? -24.240 -2.052  18.253 1.000 36.510  ? 1382 LEU AAA HB3  1 
ATOM   1979 H HG   . LEU A 1 121 ? -26.203 -3.385  18.316 1.000 40.380  ? 1382 LEU AAA HG   1 
ATOM   1980 H HD11 . LEU A 1 121 ? -25.303 -5.413  17.654 1.000 43.160  ? 1382 LEU AAA HD11 1 
ATOM   1981 H HD12 . LEU A 1 121 ? -26.061 -5.613  19.037 1.000 43.160  ? 1382 LEU AAA HD12 1 
ATOM   1982 H HD13 . LEU A 1 121 ? -24.476 -5.523  19.005 1.000 43.160  ? 1382 LEU AAA HD13 1 
ATOM   1983 H HD21 . LEU A 1 121 ? -24.687 -3.549  20.713 1.000 42.280  ? 1382 LEU AAA HD21 1 
ATOM   1984 H HD22 . LEU A 1 121 ? -26.264 -3.732  20.638 1.000 42.280  ? 1382 LEU AAA HD22 1 
ATOM   1985 H HD23 . LEU A 1 121 ? -25.611 -2.323  20.306 1.000 42.280  ? 1382 LEU AAA HD23 1 
ATOM   1986 N N    . LEU A 1 122 ? -25.640 -3.052  14.722 1.000 39.120  ? 1383 LEU AAA N    1 
ATOM   1987 C CA   . LEU A 1 122 ? -26.533 -2.385  13.740 1.000 41.030  ? 1383 LEU AAA CA   1 
ATOM   1988 C C    . LEU A 1 122 ? -27.988 -2.545  14.169 1.000 42.690  ? 1383 LEU AAA C    1 
ATOM   1989 O O    . LEU A 1 122 ? -28.566 -3.630  13.950 1.000 41.840  ? 1383 LEU AAA O    1 
ATOM   1990 C CB   . LEU A 1 122 ? -26.284 -3.012  12.372 1.000 40.920  ? 1383 LEU AAA CB   1 
ATOM   1991 C CG   . LEU A 1 122 ? -27.035 -2.401  11.199 1.000 38.600  ? 1383 LEU AAA CG   1 
ATOM   1992 C CD1  . LEU A 1 122 ? -26.818 -0.903  11.072 1.000 37.810  ? 1383 LEU AAA CD1  1 
ATOM   1993 C CD2  . LEU A 1 122 ? -26.594 -3.118  9.947  1.000 39.950  ? 1383 LEU AAA CD2  1 
ATOM   1994 H H    . LEU A 1 122 ? -25.383 -4.018  14.577 1.000 39.120  ? 1383 LEU AAA H    1 
ATOM   1995 H HA   . LEU A 1 122 ? -26.316 -1.424  13.723 1.000 41.030  ? 1383 LEU AAA HA   1 
ATOM   1996 H HB2  . LEU A 1 122 ? -25.327 -2.957  12.178 1.000 40.920  ? 1383 LEU AAA HB2  1 
ATOM   1997 H HB3  . LEU A 1 122 ? -26.521 -3.960  12.420 1.000 40.920  ? 1383 LEU AAA HB3  1 
ATOM   1998 H HG   . LEU A 1 122 ? -28.002 -2.551  11.342 1.000 38.600  ? 1383 LEU AAA HG   1 
ATOM   1999 H HD11 . LEU A 1 122 ? -27.124 -0.461  11.883 1.000 37.810  ? 1383 LEU AAA HD11 1 
ATOM   2000 H HD12 . LEU A 1 122 ? -27.318 -0.566  10.309 1.000 37.810  ? 1383 LEU AAA HD12 1 
ATOM   2001 H HD13 . LEU A 1 122 ? -25.871 -0.722  10.943 1.000 37.810  ? 1383 LEU AAA HD13 1 
ATOM   2002 H HD21 . LEU A 1 122 ? -25.635 -3.006  9.830  1.000 39.950  ? 1383 LEU AAA HD21 1 
ATOM   2003 H HD22 . LEU A 1 122 ? -27.061 -2.746  9.179  1.000 39.950  ? 1383 LEU AAA HD22 1 
ATOM   2004 H HD23 . LEU A 1 122 ? -26.802 -4.065  10.025 1.000 39.950  ? 1383 LEU AAA HD23 1 
ATOM   2005 N N    . LEU A 1 123 ? -28.538 -1.506  14.783 1.000 42.990  ? 1384 LEU AAA N    1 
ATOM   2006 C CA   . LEU A 1 123 ? -29.889 -1.547  15.380 1.000 42.120  ? 1384 LEU AAA CA   1 
ATOM   2007 C C    . LEU A 1 123 ? -30.905 -1.026  14.357 1.000 44.780  ? 1384 LEU AAA C    1 
ATOM   2008 O O    . LEU A 1 123 ? -31.000 0.195   14.232 1.000 48.830  ? 1384 LEU AAA O    1 
ATOM   2009 C CB   . LEU A 1 123 ? -29.839 -0.716  16.660 1.000 40.260  ? 1384 LEU AAA CB   1 
ATOM   2010 C CG   . LEU A 1 123 ? -28.960 -1.310  17.762 1.000 40.550  ? 1384 LEU AAA CG   1 
ATOM   2011 C CD1  . LEU A 1 123 ? -28.412 -0.240  18.673 1.000 39.850  ? 1384 LEU AAA CD1  1 
ATOM   2012 C CD2  . LEU A 1 123 ? -29.723 -2.334  18.585 1.000 39.480  ? 1384 LEU AAA CD2  1 
ATOM   2013 H H    . LEU A 1 123 ? -28.000 -0.653  14.839 1.000 42.990  ? 1384 LEU AAA H    1 
ATOM   2014 H HA   . LEU A 1 123 ? -30.106 -2.483  15.597 1.000 42.120  ? 1384 LEU AAA HA   1 
ATOM   2015 H HB2  . LEU A 1 123 ? -29.509 0.177   16.434 1.000 40.260  ? 1384 LEU AAA HB2  1 
ATOM   2016 H HB3  . LEU A 1 123 ? -30.751 -0.616  16.998 1.000 40.260  ? 1384 LEU AAA HB3  1 
ATOM   2017 H HG   . LEU A 1 123 ? -28.200 -1.773  17.331 1.000 40.550  ? 1384 LEU AAA HG   1 
ATOM   2018 H HD11 . LEU A 1 123 ? -27.875 0.384   18.154 1.000 39.850  ? 1384 LEU AAA HD11 1 
ATOM   2019 H HD12 . LEU A 1 123 ? -27.860 -0.651  19.361 1.000 39.850  ? 1384 LEU AAA HD12 1 
ATOM   2020 H HD13 . LEU A 1 123 ? -29.149 0.238   19.092 1.000 39.850  ? 1384 LEU AAA HD13 1 
ATOM   2021 H HD21 . LEU A 1 123 ? -30.494 -1.908  18.999 1.000 39.480  ? 1384 LEU AAA HD21 1 
ATOM   2022 H HD22 . LEU A 1 123 ? -29.140 -2.695  19.276 1.000 39.480  ? 1384 LEU AAA HD22 1 
ATOM   2023 H HD23 . LEU A 1 123 ? -30.024 -3.056  18.007 1.000 39.480  ? 1384 LEU AAA HD23 1 
ATOM   2024 N N    . MET A 1 124 ? -31.631 -1.936  13.682 1.000 46.330  ? 1385 MET AAA N    1 
ATOM   2025 C CA   . MET A 1 124 ? -32.476 -1.715  12.466 1.000 46.310  ? 1385 MET AAA CA   1 
ATOM   2026 C C    . MET A 1 124 ? -33.975 -1.834  12.777 1.000 48.640  ? 1385 MET AAA C    1 
ATOM   2027 O O    . MET A 1 124 ? -34.369 -2.829  13.375 1.000 52.810  ? 1385 MET AAA O    1 
ATOM   2028 C CB   . MET A 1 124 ? -32.182 -2.789  11.417 1.000 48.790  ? 1385 MET AAA CB   1 
ATOM   2029 C CG   . MET A 1 124 ? -30.745 -2.872  10.990 1.000 46.660  ? 1385 MET AAA CG   1 
ATOM   2030 S SD   . MET A 1 124 ? -30.465 -4.286  9.888  1.000 53.200  ? 1385 MET AAA SD   1 
ATOM   2031 C CE   . MET A 1 124 ? -31.568 -3.857  8.541  1.000 52.290  ? 1385 MET AAA CE   1 
ATOM   2032 H H    . MET A 1 124 ? -31.569 -2.864  14.077 1.000 46.330  ? 1385 MET AAA H    1 
ATOM   2033 H HA   . MET A 1 124 ? -32.314 -0.802  12.135 1.000 46.310  ? 1385 MET AAA HA   1 
ATOM   2034 H HB2  . MET A 1 124 ? -32.446 -3.659  11.777 1.000 48.790  ? 1385 MET AAA HB2  1 
ATOM   2035 H HB3  . MET A 1 124 ? -32.728 -2.611  10.625 1.000 48.790  ? 1385 MET AAA HB3  1 
ATOM   2036 H HG2  . MET A 1 124 ? -30.497 -2.043  10.528 1.000 46.660  ? 1385 MET AAA HG2  1 
ATOM   2037 H HG3  . MET A 1 124 ? -30.177 -2.959  11.785 1.000 46.660  ? 1385 MET AAA HG3  1 
ATOM   2038 H HE1  . MET A 1 124 ? -31.523 -4.535  7.863  1.000 52.290  ? 1385 MET AAA HE1  1 
ATOM   2039 H HE2  . MET A 1 124 ? -32.467 -3.793  8.872  1.000 52.290  ? 1385 MET AAA HE2  1 
ATOM   2040 H HE3  . MET A 1 124 ? -31.302 -3.009  8.166  1.000 52.290  ? 1385 MET AAA HE3  1 
ATOM   2041 N N    . ALA A 1 125 ? -34.783 -0.904  12.265 1.000 50.940  ? 1386 ALA AAA N    1 
ATOM   2042 C CA   . ALA A 1 125 ? -36.259 -0.842  12.421 1.000 49.170  ? 1386 ALA AAA CA   1 
ATOM   2043 C C    . ALA A 1 125 ? -36.971 -0.652  11.062 1.000 50.630  ? 1386 ALA AAA C    1 
ATOM   2044 O O    . ALA A 1 125 ? -38.203 -0.526  11.073 1.000 45.780  ? 1386 ALA AAA O    1 
ATOM   2045 C CB   . ALA A 1 125 ? -36.613 0.295   13.352 1.000 44.000  ? 1386 ALA AAA CB   1 
ATOM   2046 H H    . ALA A 1 125 ? -34.314 -0.190  11.726 1.000 50.940  ? 1386 ALA AAA H    1 
ATOM   2047 H HA   . ALA A 1 125 ? -36.570 -1.697  12.802 1.000 49.170  ? 1386 ALA AAA HA   1 
ATOM   2048 H HB1  . ALA A 1 125 ? -37.576 0.340   13.457 1.000 44.000  ? 1386 ALA AAA HB1  1 
ATOM   2049 H HB2  . ALA A 1 125 ? -36.201 0.146   14.217 1.000 44.000  ? 1386 ALA AAA HB2  1 
ATOM   2050 H HB3  . ALA A 1 125 ? -36.289 1.133   12.980 1.000 44.000  ? 1386 ALA AAA HB3  1 
ATOM   2051 N N    . SER A 1 126 ? -36.231 -0.591  9.947  1.000 48.700  ? 1387 SER AAA N    1 
ATOM   2052 C CA   . SER A 1 126 ? -36.711 -0.038  8.663  1.000 51.270  ? 1387 SER AAA CA   1 
ATOM   2053 C C    . SER A 1 126 ? -36.014 -0.733  7.490  1.000 50.030  ? 1387 SER AAA C    1 
ATOM   2054 O O    . SER A 1 126 ? -35.157 -1.614  7.706  1.000 48.280  ? 1387 SER AAA O    1 
ATOM   2055 C CB   . SER A 1 126 ? -36.514 1.464   8.638  1.000 50.500  ? 1387 SER AAA CB   1 
ATOM   2056 O OG   . SER A 1 126 ? -35.173 1.774   8.313  1.000 49.940  ? 1387 SER AAA OG   1 
ATOM   2057 H H    . SER A 1 126 ? -35.289 -0.950  10.007 1.000 48.700  ? 1387 SER AAA H    1 
ATOM   2058 H HA   . SER A 1 126 ? -37.686 -0.222  8.594  1.000 51.270  ? 1387 SER AAA HA   1 
ATOM   2059 H HB2  . SER A 1 126 ? -37.118 1.860   7.970  1.000 50.500  ? 1387 SER AAA HB2  1 
ATOM   2060 H HB3  . SER A 1 126 ? -36.737 1.836   9.521  1.000 50.500  ? 1387 SER AAA HB3  1 
ATOM   2061 H HG   . SER A 1 126 ? -35.086 2.615   8.305  0.000 49.940  ? 1387 SER AAA HG   1 
ATOM   2062 N N    . GLN A 1 127 ? -36.403 -0.350  6.279  1.000 51.810  ? 1388 GLN AAA N    1 
ATOM   2063 C CA   . GLN A 1 127 ? -35.940 -0.961  5.008  1.000 56.080  ? 1388 GLN AAA CA   1 
ATOM   2064 C C    . GLN A 1 127 ? -35.639 0.186   4.034  1.000 54.010  ? 1388 GLN AAA C    1 
ATOM   2065 O O    . GLN A 1 127 ? -36.544 0.973   3.766  1.000 52.460  ? 1388 GLN AAA O    1 
ATOM   2066 C CB   . GLN A 1 127 ? -37.006 -1.939  4.517  1.000 58.010  ? 1388 GLN AAA CB   1 
ATOM   2067 C CG   . GLN A 1 127 ? -36.636 -2.701  3.255  1.000 67.130  ? 1388 GLN AAA CG   1 
ATOM   2068 C CD   . GLN A 1 127 ? -37.740 -3.620  2.774  1.000 70.640  ? 1388 GLN AAA CD   1 
ATOM   2069 O OE1  . GLN A 1 127 ? -38.405 -4.310  3.546  1.000 78.400  ? 1388 GLN AAA OE1  1 
ATOM   2070 N NE2  . GLN A 1 127 ? -37.929 -3.659  1.470  1.000 69.540  ? 1388 GLN AAA NE2  1 
ATOM   2071 H H    . GLN A 1 127 ? -37.062 0.415   6.246  1.000 51.810  ? 1388 GLN AAA H    1 
ATOM   2072 H HA   . GLN A 1 127 ? -35.116 -1.470  5.188  1.000 56.080  ? 1388 GLN AAA HA   1 
ATOM   2073 H HB2  . GLN A 1 127 ? -37.187 -2.586  5.230  1.000 58.010  ? 1388 GLN AAA HB2  1 
ATOM   2074 H HB3  . GLN A 1 127 ? -37.833 -1.440  4.349  1.000 58.010  ? 1388 GLN AAA HB3  1 
ATOM   2075 H HG2  . GLN A 1 127 ? -36.426 -2.061  2.541  1.000 67.130  ? 1388 GLN AAA HG2  1 
ATOM   2076 H HG3  . GLN A 1 127 ? -35.833 -3.237  3.426  1.000 67.130  ? 1388 GLN AAA HG3  1 
ATOM   2077 H HE21 . GLN A 1 127 ? -38.559 -4.177  1.130  0.000 69.540  ? 1388 GLN AAA HE21 1 
ATOM   2078 H HE22 . GLN A 1 127 ? -37.426 -3.167  0.935  0.000 69.540  ? 1388 GLN AAA HE22 1 
ATOM   2079 N N    . GLU A 1 128 ? -34.392 0.291   3.564  1.000 53.390  ? 1389 GLU AAA N    1 
ATOM   2080 C CA   . GLU A 1 128 ? -33.896 1.419   2.728  1.000 51.150  ? 1389 GLU AAA CA   1 
ATOM   2081 C C    . GLU A 1 128 ? -34.377 1.189   1.293  1.000 54.200  ? 1389 GLU AAA C    1 
ATOM   2082 O O    . GLU A 1 128 ? -34.498 0.037   0.865  1.000 48.840  ? 1389 GLU AAA O    1 
ATOM   2083 C CB   . GLU A 1 128 ? -32.364 1.568   2.839  1.000 46.800  ? 1389 GLU AAA CB   1 
ATOM   2084 C CG   . GLU A 1 128 ? -31.558 0.454   2.156  1.000 48.190  ? 1389 GLU AAA CG   1 
ATOM   2085 C CD   . GLU A 1 128 ? -30.040 0.524   2.264  1.000 45.990  ? 1389 GLU AAA CD   1 
ATOM   2086 O OE1  . GLU A 1 128 ? -29.536 1.540   2.777  1.000 45.230  ? 1389 GLU AAA OE1  1 
ATOM   2087 O OE2  . GLU A 1 128 ? -29.360 -0.442  1.824  1.000 44.190  ? 1389 GLU AAA OE2  1 
ATOM   2088 H H    . GLU A 1 128 ? -33.759 -0.458  3.805  1.000 53.390  ? 1389 GLU AAA H    1 
ATOM   2089 H HA   . GLU A 1 128 ? -34.282 2.257   3.073  1.000 51.150  ? 1389 GLU AAA HA   1 
ATOM   2090 H HB2  . GLU A 1 128 ? -32.104 2.424   2.438  1.000 46.800  ? 1389 GLU AAA HB2  1 
ATOM   2091 H HB3  . GLU A 1 128 ? -32.120 1.584   3.788  1.000 46.800  ? 1389 GLU AAA HB3  1 
ATOM   2092 H HG2  . GLU A 1 128 ? -31.832 -0.411  2.529  1.000 48.190  ? 1389 GLU AAA HG2  1 
ATOM   2093 H HG3  . GLU A 1 128 ? -31.777 0.444   1.200  1.000 48.190  ? 1389 GLU AAA HG3  1 
ATOM   2094 N N    . PRO A 1 129 ? -34.665 2.273   0.527  1.000 53.760  ? 1390 PRO AAA N    1 
ATOM   2095 C CA   . PRO A 1 129 ? -34.918 2.180   -0.916 1.000 55.640  ? 1390 PRO AAA CA   1 
ATOM   2096 C C    . PRO A 1 129 ? -33.918 1.262   -1.637 1.000 57.470  ? 1390 PRO AAA C    1 
ATOM   2097 O O    . PRO A 1 129 ? -32.749 1.400   -1.288 1.000 64.490  ? 1390 PRO AAA O    1 
ATOM   2098 C CB   . PRO A 1 129 ? -34.730 3.634   -1.385 1.000 54.300  ? 1390 PRO AAA CB   1 
ATOM   2099 C CG   . PRO A 1 129 ? -35.091 4.489   -0.191 1.000 51.240  ? 1390 PRO AAA CG   1 
ATOM   2100 C CD   . PRO A 1 129 ? -34.736 3.658   1.025  1.000 53.200  ? 1390 PRO AAA CD   1 
ATOM   2101 H HA   . PRO A 1 129 ? -35.837 1.845   -1.066 1.000 55.640  ? 1390 PRO AAA HA   1 
ATOM   2102 H HB2  . PRO A 1 129 ? -33.804 3.797   -1.663 1.000 54.300  ? 1390 PRO AAA HB2  1 
ATOM   2103 H HB3  . PRO A 1 129 ? -35.313 3.836   -2.147 1.000 54.300  ? 1390 PRO AAA HB3  1 
ATOM   2104 H HG2  . PRO A 1 129 ? -34.586 5.329   -0.198 1.000 51.240  ? 1390 PRO AAA HG2  1 
ATOM   2105 H HG3  . PRO A 1 129 ? -36.046 4.709   -0.195 1.000 51.240  ? 1390 PRO AAA HG3  1 
ATOM   2106 H HD2  . PRO A 1 129 ? -33.878 3.942   1.403  1.000 53.200  ? 1390 PRO AAA HD2  1 
ATOM   2107 H HD3  . PRO A 1 129 ? -35.420 3.749   1.721  1.000 53.200  ? 1390 PRO AAA HD3  1 
ATOM   2108 N N    . GLN A 1 130 ? -34.368 0.429   -2.606 1.000 55.710  ? 1391 GLN AAA N    1 
ATOM   2109 C CA   A GLN A 1 130 ? -33.534 -0.606  -3.285 0.400 55.950  ? 1391 GLN AAA CA   1 
ATOM   2110 C CA   B GLN A 1 130 ? -33.529 -0.616  -3.275 0.600 60.800  ? 1391 GLN AAA CA   1 
ATOM   2111 C C    . GLN A 1 130 ? -32.445 0.096   -4.102 1.000 59.080  ? 1391 GLN AAA C    1 
ATOM   2112 O O    . GLN A 1 130 ? -31.416 -0.557  -4.388 1.000 62.290  ? 1391 GLN AAA O    1 
ATOM   2113 C CB   A GLN A 1 130 ? -34.368 -1.609  -4.112 0.400 52.980  ? 1391 GLN AAA CB   1 
ATOM   2114 C CB   B GLN A 1 130 ? -34.386 -1.607  -4.098 0.600 64.530  ? 1391 GLN AAA CB   1 
ATOM   2115 C CG   A GLN A 1 130 ? -35.031 -1.084  -5.383 0.400 46.460  ? 1391 GLN AAA CG   1 
ATOM   2116 C CG   B GLN A 1 130 ? -33.775 -3.005  -4.313 0.600 59.510  ? 1391 GLN AAA CG   1 
ATOM   2117 C CD   A GLN A 1 130 ? -36.064 -2.050  -5.925 0.400 39.340  ? 1391 GLN AAA CD   1 
ATOM   2118 C CD   B GLN A 1 130 ? -34.080 -4.065  -3.265 0.600 57.400  ? 1391 GLN AAA CD   1 
ATOM   2119 O OE1  A GLN A 1 130 ? -37.246 -1.739  -5.969 0.400 31.610  ? 1391 GLN AAA OE1  1 
ATOM   2120 O OE1  B GLN A 1 130 ? -35.216 -4.306  -2.861 0.600 51.520  ? 1391 GLN AAA OE1  1 
ATOM   2121 N NE2  A GLN A 1 130 ? -35.633 -3.231  -6.340 0.400 32.320  ? 1391 GLN AAA NE2  1 
ATOM   2122 N NE2  B GLN A 1 130 ? -33.048 -4.764  -2.828 0.600 49.890  ? 1391 GLN AAA NE2  1 
ATOM   2123 H H    . GLN A 1 130 ? -35.337 0.533   -2.872 1.000 55.710  ? 1391 GLN AAA H    1 
ATOM   2124 H HA   A GLN A 1 130 ? -33.096 -1.156  -2.595 0.400 55.950  ? 1391 GLN AAA HA   1 
ATOM   2125 H HA   B GLN A 1 130 ? -33.100 -1.165  -2.579 0.600 60.800  ? 1391 GLN AAA HA   1 
ATOM   2126 H HB2  A GLN A 1 130 ? -33.789 -2.355  -4.374 0.400 52.980  ? 1391 GLN AAA HB2  1 
ATOM   2127 H HB2  B GLN A 1 130 ? -35.249 -1.721  -3.648 0.600 64.530  ? 1391 GLN AAA HB2  1 
ATOM   2128 H HB3  A GLN A 1 130 ? -35.079 -1.969  -3.541 0.400 52.980  ? 1391 GLN AAA HB3  1 
ATOM   2129 H HB3  B GLN A 1 130 ? -34.557 -1.214  -4.979 0.600 64.530  ? 1391 GLN AAA HB3  1 
ATOM   2130 H HG2  A GLN A 1 130 ? -35.463 -0.225  -5.190 0.400 46.460  ? 1391 GLN AAA HG2  1 
ATOM   2131 H HG2  B GLN A 1 130 ? -34.086 -3.365  -5.171 0.600 59.510  ? 1391 GLN AAA HG2  1 
ATOM   2132 H HG3  A GLN A 1 130 ? -34.344 -0.930  -6.066 0.400 46.460  ? 1391 GLN AAA HG3  1 
ATOM   2133 H HG3  B GLN A 1 130 ? -32.798 -2.927  -4.354 0.600 59.510  ? 1391 GLN AAA HG3  1 
ATOM   2134 H HE21 A GLN A 1 130 ? -36.205 -3.822  -6.663 0.000 32.320  ? 1391 GLN AAA HE21 1 
ATOM   2135 H HE21 B GLN A 1 130 ? -33.166 -5.393  -2.219 0.000 49.890  ? 1391 GLN AAA HE21 1 
ATOM   2136 H HE22 A GLN A 1 130 ? -34.773 -3.429  -6.294 0.000 32.320  ? 1391 GLN AAA HE22 1 
ATOM   2137 H HE22 B GLN A 1 130 ? -32.239 -4.603  -3.145 0.000 49.890  ? 1391 GLN AAA HE22 1 
ATOM   2138 N N    . ARG A 1 131 ? -32.656 1.377   -4.430 1.000 61.030  ? 1392 ARG AAA N    1 
ATOM   2139 C CA   . ARG A 1 131 ? -31.683 2.220   -5.197 1.000 64.480  ? 1392 ARG AAA CA   1 
ATOM   2140 C C    . ARG A 1 131 ? -30.448 2.514   -4.337 1.000 63.710  ? 1392 ARG AAA C    1 
ATOM   2141 O O    . ARG A 1 131 ? -29.361 2.649   -4.911 1.000 64.770  ? 1392 ARG AAA O    1 
ATOM   2142 C CB   . ARG A 1 131 ? -32.293 3.542   -5.677 1.000 66.680  ? 1392 ARG AAA CB   1 
ATOM   2143 C CG   . ARG A 1 131 ? -33.613 3.922   -5.016 1.000 81.080  ? 1392 ARG AAA CG   1 
ATOM   2144 C CD   . ARG A 1 131 ? -34.073 5.313   -5.410 1.000 94.530  ? 1392 ARG AAA CD   1 
ATOM   2145 N NE   . ARG A 1 131 ? -33.475 6.338   -4.548 1.000 102.160 ? 1392 ARG AAA NE   1 
ATOM   2146 C CZ   . ARG A 1 131 ? -34.086 6.963   -3.533 1.000 95.830  ? 1392 ARG AAA CZ   1 
ATOM   2147 N NH1  . ARG A 1 131 ? -35.344 6.684   -3.233 1.000 93.990  ? 1392 ARG AAA NH1  1 
ATOM   2148 N NH2  . ARG A 1 131 ? -33.435 7.865   -2.815 1.000 90.950  ? 1392 ARG AAA NH2  1 
ATOM   2149 H H    . ARG A 1 131 ? -33.532 1.783   -4.133 1.000 61.030  ? 1392 ARG AAA H    1 
ATOM   2150 H HA   . ARG A 1 131 ? -31.395 1.718   -5.994 1.000 64.480  ? 1392 ARG AAA HA   1 
ATOM   2151 H HB2  . ARG A 1 131 ? -31.648 4.261   -5.511 1.000 66.680  ? 1392 ARG AAA HB2  1 
ATOM   2152 H HB3  . ARG A 1 131 ? -32.439 3.485   -6.644 1.000 66.680  ? 1392 ARG AAA HB3  1 
ATOM   2153 H HG2  . ARG A 1 131 ? -34.302 3.273   -5.272 1.000 81.080  ? 1392 ARG AAA HG2  1 
ATOM   2154 H HG3  . ARG A 1 131 ? -33.510 3.883   -4.041 1.000 81.080  ? 1392 ARG AAA HG3  1 
ATOM   2155 H HD2  . ARG A 1 131 ? -33.826 5.482   -6.344 1.000 94.530  ? 1392 ARG AAA HD2  1 
ATOM   2156 H HD3  . ARG A 1 131 ? -35.051 5.359   -5.349 1.000 94.530  ? 1392 ARG AAA HD3  1 
ATOM   2157 H HE   . ARG A 1 131 ? -32.648 6.568   -4.702 1.000 102.160 ? 1392 ARG AAA HE   1 
ATOM   2158 H HH11 . ARG A 1 131 ? -35.783 6.084   -3.702 1.000 93.990  ? 1392 ARG AAA HH11 1 
ATOM   2159 H HH12 . ARG A 1 131 ? -35.737 7.099   -2.565 1.000 93.990  ? 1392 ARG AAA HH12 1 
ATOM   2160 H HH21 . ARG A 1 131 ? -32.596 8.055   -3.006 1.000 90.950  ? 1392 ARG AAA HH21 1 
ATOM   2161 H HH22 . ARG A 1 131 ? -33.843 8.273   -2.149 1.000 90.950  ? 1392 ARG AAA HH22 1 
ATOM   2162 N N    . MET A 1 132 ? -30.610 2.590   -3.013 1.000 59.670  ? 1393 MET AAA N    1 
ATOM   2163 C CA   . MET A 1 132 ? -29.523 2.883   -2.038 1.000 55.070  ? 1393 MET AAA CA   1 
ATOM   2164 C C    . MET A 1 132 ? -28.731 1.615   -1.652 1.000 54.770  ? 1393 MET AAA C    1 
ATOM   2165 O O    . MET A 1 132 ? -27.652 1.743   -1.054 1.000 59.390  ? 1393 MET AAA O    1 
ATOM   2166 C CB   . MET A 1 132 ? -30.108 3.508   -0.769 1.000 54.880  ? 1393 MET AAA CB   1 
ATOM   2167 C CG   . MET A 1 132 ? -30.749 4.875   -0.973 1.000 52.720  ? 1393 MET AAA CG   1 
ATOM   2168 S SD   . MET A 1 132 ? -30.962 5.717   0.637  1.000 58.410  ? 1393 MET AAA SD   1 
ATOM   2169 C CE   . MET A 1 132 ? -32.071 7.082   0.258  1.000 61.680  ? 1393 MET AAA CE   1 
ATOM   2170 H H    . MET A 1 132 ? -31.548 2.433   -2.673 1.000 59.670  ? 1393 MET AAA H    1 
ATOM   2171 H HA   . MET A 1 132 ? -28.890 3.511   -2.456 1.000 55.070  ? 1393 MET AAA HA   1 
ATOM   2172 H HB2  . MET A 1 132 ? -30.784 2.902   -0.404 1.000 54.880  ? 1393 MET AAA HB2  1 
ATOM   2173 H HB3  . MET A 1 132 ? -29.394 3.598   -0.107 1.000 54.880  ? 1393 MET AAA HB3  1 
ATOM   2174 H HG2  . MET A 1 132 ? -30.179 5.414   -1.563 1.000 52.720  ? 1393 MET AAA HG2  1 
ATOM   2175 H HG3  . MET A 1 132 ? -31.619 4.761   -1.412 1.000 52.720  ? 1393 MET AAA HG3  1 
ATOM   2176 H HE1  . MET A 1 132 ? -32.241 7.587   1.057  1.000 61.680  ? 1393 MET AAA HE1  1 
ATOM   2177 H HE2  . MET A 1 132 ? -31.664 7.650   -0.400 1.000 61.680  ? 1393 MET AAA HE2  1 
ATOM   2178 H HE3  . MET A 1 132 ? -32.902 6.734   -0.086 1.000 61.680  ? 1393 MET AAA HE3  1 
ATOM   2179 N N    . SER A 1 133 ? -29.196 0.418   -1.988 1.000 50.840  ? 1394 SER AAA N    1 
ATOM   2180 C CA   . SER A 1 133 ? -28.533 -0.844  -1.582 1.000 50.920  ? 1394 SER AAA CA   1 
ATOM   2181 C C    . SER A 1 133 ? -27.508 -1.308  -2.608 1.000 49.800  ? 1394 SER AAA C    1 
ATOM   2182 O O    . SER A 1 133 ? -27.037 -2.439  -2.432 1.000 53.240  ? 1394 SER AAA O    1 
ATOM   2183 C CB   . SER A 1 133 ? -29.547 -1.914  -1.338 1.000 60.140  ? 1394 SER AAA CB   1 
ATOM   2184 O OG   . SER A 1 133 ? -30.720 -1.347  -0.766 1.000 70.820  ? 1394 SER AAA OG   1 
ATOM   2185 H H    . SER A 1 133 ? -30.038 0.375   -2.544 1.000 50.840  ? 1394 SER AAA H    1 
ATOM   2186 H HA   . SER A 1 133 ? -28.043 -0.675  -0.732 1.000 50.920  ? 1394 SER AAA HA   1 
ATOM   2187 H HB2  . SER A 1 133 ? -29.769 -2.353  -2.190 1.000 60.140  ? 1394 SER AAA HB2  1 
ATOM   2188 H HB3  . SER A 1 133 ? -29.169 -2.587  -0.728 1.000 60.140  ? 1394 SER AAA HB3  1 
ATOM   2189 H HG   . SER A 1 133 ? -31.282 -1.966  -0.635 0.000 70.820  ? 1394 SER AAA HG   1 
ATOM   2190 N N    . ARG A 1 134 ? -27.143 -0.488  -3.602 1.000 58.030  ? 1395 ARG AAA N    1 
ATOM   2191 C CA   . ARG A 1 134 ? -26.234 -0.898  -4.714 1.000 63.910  ? 1395 ARG AAA CA   1 
ATOM   2192 C C    . ARG A 1 134 ? -25.018 -1.625  -4.110 1.000 61.150  ? 1395 ARG AAA C    1 
ATOM   2193 O O    . ARG A 1 134 ? -24.779 -2.792  -4.474 1.000 56.450  ? 1395 ARG AAA O    1 
ATOM   2194 C CB   . ARG A 1 134 ? -25.833 0.301   -5.590 1.000 76.670  ? 1395 ARG AAA CB   1 
ATOM   2195 C CG   . ARG A 1 134 ? -26.852 0.692   -6.666 1.000 93.130  ? 1395 ARG AAA CG   1 
ATOM   2196 C CD   . ARG A 1 134 ? -26.750 2.109   -7.269 1.000 96.970  ? 1395 ARG AAA CD   1 
ATOM   2197 N NE   . ARG A 1 134 ? -25.403 2.478   -7.738 1.000 110.560 ? 1395 ARG AAA NE   1 
ATOM   2198 C CZ   . ARG A 1 134 ? -24.607 3.437   -7.227 1.000 109.920 ? 1395 ARG AAA CZ   1 
ATOM   2199 N NH1  . ARG A 1 134 ? -25.002 4.195   -6.218 1.000 110.010 ? 1395 ARG AAA NH1  1 
ATOM   2200 N NH2  . ARG A 1 134 ? -23.403 3.643   -7.737 1.000 100.240 ? 1395 ARG AAA NH2  1 
ATOM   2201 H H    . ARG A 1 134 ? -27.509 0.453   -3.587 1.000 58.030  ? 1395 ARG AAA H    1 
ATOM   2202 H HA   . ARG A 1 134 ? -26.722 -1.519  -5.303 1.000 63.910  ? 1395 ARG AAA HA   1 
ATOM   2203 H HB2  . ARG A 1 134 ? -25.688 1.077   -5.009 1.000 76.670  ? 1395 ARG AAA HB2  1 
ATOM   2204 H HB3  . ARG A 1 134 ? -24.984 0.093   -6.033 1.000 76.670  ? 1395 ARG AAA HB3  1 
ATOM   2205 H HG2  . ARG A 1 134 ? -26.781 0.069   -7.420 1.000 93.130  ? 1395 ARG AAA HG2  1 
ATOM   2206 H HG3  . ARG A 1 134 ? -27.758 0.617   -6.296 1.000 93.130  ? 1395 ARG AAA HG3  1 
ATOM   2207 H HD2  . ARG A 1 134 ? -27.367 2.182   -8.028 1.000 96.970  ? 1395 ARG AAA HD2  1 
ATOM   2208 H HD3  . ARG A 1 134 ? -27.029 2.767   -6.597 1.000 96.970  ? 1395 ARG AAA HD3  1 
ATOM   2209 H HE   . ARG A 1 134 ? -25.073 2.040   -8.416 1.000 110.560 ? 1395 ARG AAA HE   1 
ATOM   2210 H HH11 . ARG A 1 134 ? -25.800 4.077   -5.868 1.000 110.010 ? 1395 ARG AAA HH11 1 
ATOM   2211 H HH12 . ARG A 1 134 ? -24.466 4.815   -5.900 1.000 110.010 ? 1395 ARG AAA HH12 1 
ATOM   2212 H HH21 . ARG A 1 134 ? -23.123 3.151   -8.412 1.000 100.240 ? 1395 ARG AAA HH21 1 
ATOM   2213 H HH22 . ARG A 1 134 ? -22.886 4.271   -7.400 1.000 100.240 ? 1395 ARG AAA HH22 1 
ATOM   2214 N N    . ASN A 1 135 ? -24.327 -1.001  -3.151 1.000 58.730  ? 1396 ASN AAA N    1 
ATOM   2215 C CA   . ASN A 1 135 ? -22.985 -1.428  -2.656 1.000 58.460  ? 1396 ASN AAA CA   1 
ATOM   2216 C C    . ASN A 1 135 ? -23.042 -2.120  -1.280 1.000 54.590  ? 1396 ASN AAA C    1 
ATOM   2217 O O    . ASN A 1 135 ? -21.979 -2.387  -0.716 1.000 46.790  ? 1396 ASN AAA O    1 
ATOM   2218 C CB   . ASN A 1 135 ? -22.077 -0.206  -2.627 1.000 61.830  ? 1396 ASN AAA CB   1 
ATOM   2219 C CG   . ASN A 1 135 ? -21.944 0.405   -4.005 1.000 64.380  ? 1396 ASN AAA CG   1 
ATOM   2220 O OD1  . ASN A 1 135 ? -21.508 -0.289  -4.920 1.000 65.860  ? 1396 ASN AAA OD1  1 
ATOM   2221 N ND2  . ASN A 1 135 ? -22.332 1.667   -4.158 1.000 58.440  ? 1396 ASN AAA ND2  1 
ATOM   2222 H H    . ASN A 1 135 ? -24.764 -0.185  -2.747 1.000 58.730  ? 1396 ASN AAA H    1 
ATOM   2223 H HA   . ASN A 1 135 ? -22.611 -2.082  -3.292 1.000 58.460  ? 1396 ASN AAA HA   1 
ATOM   2224 H HB2  . ASN A 1 135 ? -22.448 0.450   -2.003 1.000 61.830  ? 1396 ASN AAA HB2  1 
ATOM   2225 H HB3  . ASN A 1 135 ? -21.197 -0.473  -2.291 1.000 61.830  ? 1396 ASN AAA HB3  1 
ATOM   2226 H HD21 . ASN A 1 135 ? -22.269 2.056   -4.949 0.000 58.440  ? 1396 ASN AAA HD21 1 
ATOM   2227 H HD22 . ASN A 1 135 ? -22.654 2.118   -3.469 0.000 58.440  ? 1396 ASN AAA HD22 1 
ATOM   2228 N N    . PHE A 1 136 ? -24.241 -2.442  -0.791 1.000 51.320  ? 1397 PHE AAA N    1 
ATOM   2229 C CA   . PHE A 1 136 ? -24.494 -3.004  0.551  1.000 50.880  ? 1397 PHE AAA CA   1 
ATOM   2230 C C    . PHE A 1 136 ? -23.537 -4.163  0.850  1.000 55.780  ? 1397 PHE AAA C    1 
ATOM   2231 O O    . PHE A 1 136 ? -22.857 -4.111  1.910  1.000 52.000  ? 1397 PHE AAA O    1 
ATOM   2232 C CB   . PHE A 1 136 ? -25.932 -3.487  0.687  1.000 46.850  ? 1397 PHE AAA CB   1 
ATOM   2233 C CG   . PHE A 1 136 ? -26.239 -4.033  2.054  1.000 46.880  ? 1397 PHE AAA CG   1 
ATOM   2234 C CD1  . PHE A 1 136 ? -26.442 -3.174  3.132  1.000 45.680  ? 1397 PHE AAA CD1  1 
ATOM   2235 C CD2  . PHE A 1 136 ? -26.250 -5.402  2.280  1.000 47.690  ? 1397 PHE AAA CD2  1 
ATOM   2236 C CE1  . PHE A 1 136 ? -26.747 -3.684  4.383  1.000 43.530  ? 1397 PHE AAA CE1  1 
ATOM   2237 C CE2  . PHE A 1 136 ? -26.514 -5.907  3.546  1.000 45.940  ? 1397 PHE AAA CE2  1 
ATOM   2238 C CZ   . PHE A 1 136 ? -26.778 -5.045  4.587  1.000 44.980  ? 1397 PHE AAA CZ   1 
ATOM   2239 H H    . PHE A 1 136 ? -25.021 -2.277  -1.411 1.000 51.320  ? 1397 PHE AAA H    1 
ATOM   2240 H HA   . PHE A 1 136 ? -24.331 -2.297  1.226  1.000 50.880  ? 1397 PHE AAA HA   1 
ATOM   2241 H HB2  . PHE A 1 136 ? -26.531 -2.738  0.486  1.000 46.850  ? 1397 PHE AAA HB2  1 
ATOM   2242 H HB3  . PHE A 1 136 ? -26.093 -4.177  0.010  1.000 46.850  ? 1397 PHE AAA HB3  1 
ATOM   2243 H HD1  . PHE A 1 136 ? -26.386 -2.241  3.001  1.000 45.680  ? 1397 PHE AAA HD1  1 
ATOM   2244 H HD2  . PHE A 1 136 ? -26.076 -5.994  1.566  1.000 47.690  ? 1397 PHE AAA HD2  1 
ATOM   2245 H HE1  . PHE A 1 136 ? -26.883 -3.096  5.109  1.000 43.530  ? 1397 PHE AAA HE1  1 
ATOM   2246 H HE2  . PHE A 1 136 ? -26.536 -6.840  3.690  1.000 45.940  ? 1397 PHE AAA HE2  1 
ATOM   2247 H HZ   . PHE A 1 136 ? -26.986 -5.389  5.441  1.000 44.980  ? 1397 PHE AAA HZ   1 
ATOM   2248 N N    . VAL A 1 137 ? -23.497 -5.180  -0.010 1.000 52.070  ? 1398 VAL AAA N    1 
ATOM   2249 C CA   . VAL A 1 137 ? -22.650 -6.390  0.227  1.000 55.200  ? 1398 VAL AAA CA   1 
ATOM   2250 C C    . VAL A 1 137 ? -21.175 -5.975  0.196  1.000 55.710  ? 1398 VAL AAA C    1 
ATOM   2251 O O    . VAL A 1 137 ? -20.350 -6.545  0.945  1.000 53.080  ? 1398 VAL AAA O    1 
ATOM   2252 C CB   . VAL A 1 137 ? -22.953 -7.480  -0.815 1.000 57.110  ? 1398 VAL AAA CB   1 
ATOM   2253 C CG1  . VAL A 1 137 ? -21.980 -8.647  -0.727 1.000 54.120  ? 1398 VAL AAA CG1  1 
ATOM   2254 C CG2  . VAL A 1 137 ? -24.393 -7.938  -0.680 1.000 60.290  ? 1398 VAL AAA CG2  1 
ATOM   2255 H H    . VAL A 1 137 ? -24.058 -5.128  -0.848 1.000 52.070  ? 1398 VAL AAA H    1 
ATOM   2256 H HA   . VAL A 1 137 ? -22.854 -6.740  1.113  1.000 55.200  ? 1398 VAL AAA HA   1 
ATOM   2257 H HB   . VAL A 1 137 ? -22.837 -7.072  -1.708 1.000 57.110  ? 1398 VAL AAA HB   1 
ATOM   2258 H HG11 . VAL A 1 137 ? -21.074 -8.327  -0.880 1.000 54.120  ? 1398 VAL AAA HG11 1 
ATOM   2259 H HG12 . VAL A 1 137 ? -22.207 -9.311  -1.401 1.000 54.120  ? 1398 VAL AAA HG12 1 
ATOM   2260 H HG13 . VAL A 1 137 ? -22.036 -9.051  0.157  1.000 54.120  ? 1398 VAL AAA HG13 1 
ATOM   2261 H HG21 . VAL A 1 137 ? -24.537 -8.298  0.212  1.000 60.290  ? 1398 VAL AAA HG21 1 
ATOM   2262 H HG22 . VAL A 1 137 ? -24.578 -8.627  -1.342 1.000 60.290  ? 1398 VAL AAA HG22 1 
ATOM   2263 H HG23 . VAL A 1 137 ? -24.989 -7.183  -0.824 1.000 60.290  ? 1398 VAL AAA HG23 1 
ATOM   2264 N N    . ARG A 1 138 ? -20.851 -5.020  -0.664 1.000 53.460  ? 1399 ARG AAA N    1 
ATOM   2265 C CA   . ARG A 1 138 ? -19.470 -4.524  -0.787 1.000 59.130  ? 1399 ARG AAA CA   1 
ATOM   2266 C C    . ARG A 1 138 ? -18.999 -4.042  0.589  1.000 57.560  ? 1399 ARG AAA C    1 
ATOM   2267 O O    . ARG A 1 138 ? -17.923 -4.500  1.027  1.000 57.930  ? 1399 ARG AAA O    1 
ATOM   2268 C CB   . ARG A 1 138 ? -19.379 -3.404  -1.821 1.000 62.560  ? 1399 ARG AAA CB   1 
ATOM   2269 C CG   . ARG A 1 138 ? -17.948 -2.953  -2.057 1.000 75.380  ? 1399 ARG AAA CG   1 
ATOM   2270 C CD   . ARG A 1 138 ? -17.388 -3.472  -3.359 1.000 91.110  ? 1399 ARG AAA CD   1 
ATOM   2271 N NE   . ARG A 1 138 ? -17.724 -2.513  -4.398 1.000 100.070 ? 1399 ARG AAA NE   1 
ATOM   2272 C CZ   . ARG A 1 138 ? -18.387 -2.775  -5.521 1.000 112.440 ? 1399 ARG AAA CZ   1 
ATOM   2273 N NH1  . ARG A 1 138 ? -18.786 -4.005  -5.823 1.000 108.050 ? 1399 ARG AAA NH1  1 
ATOM   2274 N NH2  . ARG A 1 138 ? -18.618 -1.782  -6.363 1.000 119.160 ? 1399 ARG AAA NH2  1 
ATOM   2275 H H    . ARG A 1 138 ? -21.571 -4.622  -1.250 1.000 53.460  ? 1399 ARG AAA H    1 
ATOM   2276 H HA   . ARG A 1 138 ? -18.896 -5.268  -1.082 1.000 59.130  ? 1399 ARG AAA HA   1 
ATOM   2277 H HB2  . ARG A 1 138 ? -19.768 -3.724  -2.662 1.000 62.560  ? 1399 ARG AAA HB2  1 
ATOM   2278 H HB3  . ARG A 1 138 ? -19.917 -2.647  -1.509 1.000 62.560  ? 1399 ARG AAA HB3  1 
ATOM   2279 H HG2  . ARG A 1 138 ? -17.915 -1.973  -2.064 1.000 75.380  ? 1399 ARG AAA HG2  1 
ATOM   2280 H HG3  . ARG A 1 138 ? -17.383 -3.268  -1.319 1.000 75.380  ? 1399 ARG AAA HG3  1 
ATOM   2281 H HD2  . ARG A 1 138 ? -16.417 -3.583  -3.271 1.000 91.110  ? 1399 ARG AAA HD2  1 
ATOM   2282 H HD3  . ARG A 1 138 ? -17.772 -4.355  -3.546 1.000 91.110  ? 1399 ARG AAA HD3  1 
ATOM   2283 H HE   . ARG A 1 138 ? -17.473 -1.686  -4.286 1.000 100.070 ? 1399 ARG AAA HE   1 
ATOM   2284 H HH11 . ARG A 1 138 ? -18.612 -4.669  -5.273 1.000 108.050 ? 1399 ARG AAA HH11 1 
ATOM   2285 H HH12 . ARG A 1 138 ? -19.223 -4.152  -6.572 1.000 108.050 ? 1399 ARG AAA HH12 1 
ATOM   2286 H HH21 . ARG A 1 138 ? -18.334 -0.970  -6.172 1.000 119.160 ? 1399 ARG AAA HH21 1 
ATOM   2287 H HH22 . ARG A 1 138 ? -19.055 -1.935  -7.112 1.000 119.160 ? 1399 ARG AAA HH22 1 
ATOM   2288 N N    . TYR A 1 139 ? -19.752 -3.135  1.222  1.000 49.370  ? 1400 TYR AAA N    1 
ATOM   2289 C CA   . TYR A 1 139 ? -19.362 -2.482  2.497  1.000 55.270  ? 1400 TYR AAA CA   1 
ATOM   2290 C C    . TYR A 1 139 ? -19.325 -3.480  3.660  1.000 49.310  ? 1400 TYR AAA C    1 
ATOM   2291 O O    . TYR A 1 139 ? -18.495 -3.283  4.544  1.000 45.250  ? 1400 TYR AAA O    1 
ATOM   2292 C CB   . TYR A 1 139 ? -20.321 -1.368  2.884  1.000 56.350  ? 1400 TYR AAA CB   1 
ATOM   2293 C CG   . TYR A 1 139 ? -20.411 -0.261  1.878  1.000 56.640  ? 1400 TYR AAA CG   1 
ATOM   2294 C CD1  . TYR A 1 139 ? -19.293 0.261   1.237  1.000 55.790  ? 1400 TYR AAA CD1  1 
ATOM   2295 C CD2  . TYR A 1 139 ? -21.639 0.297   1.611  1.000 55.150  ? 1400 TYR AAA CD2  1 
ATOM   2296 C CE1  . TYR A 1 139 ? -19.411 1.303   0.327  1.000 55.450  ? 1400 TYR AAA CE1  1 
ATOM   2297 C CE2  . TYR A 1 139 ? -21.775 1.343   0.719  1.000 61.350  ? 1400 TYR AAA CE2  1 
ATOM   2298 C CZ   . TYR A 1 139 ? -20.664 1.840   0.065  1.000 59.660  ? 1400 TYR AAA CZ   1 
ATOM   2299 O OH   . TYR A 1 139 ? -20.917 2.871   -0.791 1.000 63.320  ? 1400 TYR AAA OH   1 
ATOM   2300 H H    . TYR A 1 139 ? -20.634 -2.892  0.794  1.000 49.370  ? 1400 TYR AAA H    1 
ATOM   2301 H HA   . TYR A 1 139 ? -18.448 -2.112  2.396  1.000 55.270  ? 1400 TYR AAA HA   1 
ATOM   2302 H HB2  . TYR A 1 139 ? -21.211 -1.757  3.016  1.000 56.350  ? 1400 TYR AAA HB2  1 
ATOM   2303 H HB3  . TYR A 1 139 ? -20.035 -0.998  3.745  1.000 56.350  ? 1400 TYR AAA HB3  1 
ATOM   2304 H HD1  . TYR A 1 139 ? -18.441 -0.089  1.437  1.000 55.790  ? 1400 TYR AAA HD1  1 
ATOM   2305 H HD2  . TYR A 1 139 ? -22.405 -0.040  2.045  1.000 55.150  ? 1400 TYR AAA HD2  1 
ATOM   2306 H HE1  . TYR A 1 139 ? -18.645 1.648   -0.101 1.000 55.450  ? 1400 TYR AAA HE1  1 
ATOM   2307 H HE2  . TYR A 1 139 ? -22.627 1.706   0.543  1.000 61.350  ? 1400 TYR AAA HE2  1 
ATOM   2308 H HH   . TYR A 1 139 ? -20.664 2.663   -1.584 0.000 63.320  ? 1400 TYR AAA HH   1 
ATOM   2309 N N    . VAL A 1 140 ? -20.172 -4.505  3.650  1.000 44.400  ? 1401 VAL AAA N    1 
ATOM   2310 C CA   . VAL A 1 140 ? -20.193 -5.556  4.703  1.000 46.510  ? 1401 VAL AAA CA   1 
ATOM   2311 C C    . VAL A 1 140 ? -18.955 -6.416  4.540  1.000 45.500  ? 1401 VAL AAA C    1 
ATOM   2312 O O    . VAL A 1 140 ? -18.423 -6.896  5.559  1.000 46.230  ? 1401 VAL AAA O    1 
ATOM   2313 C CB   . VAL A 1 140 ? -21.466 -6.410  4.638  1.000 49.750  ? 1401 VAL AAA CB   1 
ATOM   2314 C CG1  . VAL A 1 140 ? -21.380 -7.641  5.546  1.000 49.280  ? 1401 VAL AAA CG1  1 
ATOM   2315 C CG2  . VAL A 1 140 ? -22.678 -5.549  4.975  1.000 50.830  ? 1401 VAL AAA CG2  1 
ATOM   2316 H H    . VAL A 1 140 ? -20.828 -4.562  2.885  1.000 44.400  ? 1401 VAL AAA H    1 
ATOM   2317 H HA   . VAL A 1 140 ? -20.160 -5.120  5.573  1.000 46.510  ? 1401 VAL AAA HA   1 
ATOM   2318 H HB   . VAL A 1 140 ? -21.557 -6.731  3.707  1.000 49.750  ? 1401 VAL AAA HB   1 
ATOM   2319 H HG11 . VAL A 1 140 ? -20.629 -8.195  5.272  1.000 49.280  ? 1401 VAL AAA HG11 1 
ATOM   2320 H HG12 . VAL A 1 140 ? -22.204 -8.154  5.477  1.000 49.280  ? 1401 VAL AAA HG12 1 
ATOM   2321 H HG13 . VAL A 1 140 ? -21.253 -7.357  6.468  1.000 49.280  ? 1401 VAL AAA HG13 1 
ATOM   2322 H HG21 . VAL A 1 140 ? -22.579 -5.185  5.872  1.000 50.830  ? 1401 VAL AAA HG21 1 
ATOM   2323 H HG22 . VAL A 1 140 ? -23.484 -6.092  4.933  1.000 50.830  ? 1401 VAL AAA HG22 1 
ATOM   2324 H HG23 . VAL A 1 140 ? -22.746 -4.819  4.335  1.000 50.830  ? 1401 VAL AAA HG23 1 
ATOM   2325 N N    . GLN A 1 141 ? -18.559 -6.602  3.290  1.000 52.750  ? 1402 GLN AAA N    1 
ATOM   2326 C CA   . GLN A 1 141 ? -17.398 -7.427  2.888  1.000 52.750  ? 1402 GLN AAA CA   1 
ATOM   2327 C C    . GLN A 1 141 ? -16.159 -6.617  3.269  1.000 46.740  ? 1402 GLN AAA C    1 
ATOM   2328 O O    . GLN A 1 141 ? -15.184 -7.209  3.696  1.000 45.800  ? 1402 GLN AAA O    1 
ATOM   2329 C CB   . GLN A 1 141 ? -17.553 -7.808  1.409  1.000 57.340  ? 1402 GLN AAA CB   1 
ATOM   2330 C CG   . GLN A 1 141 ? -16.739 -9.023  0.993  1.000 65.770  ? 1402 GLN AAA CG   1 
ATOM   2331 C CD   . GLN A 1 141 ? -17.296 -10.307 1.557  1.000 73.110  ? 1402 GLN AAA CD   1 
ATOM   2332 O OE1  . GLN A 1 141 ? -18.504 -10.425 1.764  1.000 71.470  ? 1402 GLN AAA OE1  1 
ATOM   2333 N NE2  . GLN A 1 141 ? -16.414 -11.273 1.809  1.000 67.410  ? 1402 GLN AAA NE2  1 
ATOM   2334 H H    . GLN A 1 141 ? -19.104 -6.138  2.577  1.000 52.750  ? 1402 GLN AAA H    1 
ATOM   2335 H HA   . GLN A 1 141 ? -17.425 -8.272  3.394  1.000 52.750  ? 1402 GLN AAA HA   1 
ATOM   2336 H HB2  . GLN A 1 141 ? -18.500 -7.985  1.230  1.000 57.340  ? 1402 GLN AAA HB2  1 
ATOM   2337 H HB3  . GLN A 1 141 ? -17.283 -7.043  0.860  1.000 57.340  ? 1402 GLN AAA HB3  1 
ATOM   2338 H HG2  . GLN A 1 141 ? -16.726 -9.083  0.014  1.000 65.770  ? 1402 GLN AAA HG2  1 
ATOM   2339 H HG3  . GLN A 1 141 ? -15.814 -8.913  1.301  1.000 65.770  ? 1402 GLN AAA HG3  1 
ATOM   2340 H HE21 . GLN A 1 141 ? -16.687 -12.046 2.140  0.000 67.410  ? 1402 GLN AAA HE21 1 
ATOM   2341 H HE22 . GLN A 1 141 ? -15.555 -11.142 1.645  0.000 67.410  ? 1402 GLN AAA HE22 1 
ATOM   2342 N N    . GLY A 1 142 ? -16.242 -5.294  3.207  1.000 45.470  ? 1403 GLY AAA N    1 
ATOM   2343 C CA   . GLY A 1 142 ? -15.119 -4.408  3.555  1.000 46.100  ? 1403 GLY AAA CA   1 
ATOM   2344 C C    . GLY A 1 142 ? -14.876 -4.406  5.044  1.000 49.410  ? 1403 GLY AAA C    1 
ATOM   2345 O O    . GLY A 1 142 ? -13.712 -4.318  5.487  1.000 48.650  ? 1403 GLY AAA O    1 
ATOM   2346 H H    . GLY A 1 142 ? -17.116 -4.886  2.907  1.000 45.470  ? 1403 GLY AAA H    1 
ATOM   2347 H HA2  . GLY A 1 142 ? -14.306 -4.716  3.082  1.000 46.100  ? 1403 GLY AAA HA2  1 
ATOM   2348 H HA3  . GLY A 1 142 ? -15.324 -3.490  3.247  1.000 46.100  ? 1403 GLY AAA HA3  1 
ATOM   2349 N N    . LEU A 1 143 ? -15.953 -4.522  5.803  1.000 52.890  ? 1404 LEU AAA N    1 
ATOM   2350 C CA   . LEU A 1 143 ? -15.898 -4.643  7.276  1.000 47.780  ? 1404 LEU AAA CA   1 
ATOM   2351 C C    . LEU A 1 143 ? -15.337 -6.024  7.649  1.000 49.250  ? 1404 LEU AAA C    1 
ATOM   2352 O O    . LEU A 1 143 ? -14.426 -6.052  8.465  1.000 54.400  ? 1404 LEU AAA O    1 
ATOM   2353 C CB   . LEU A 1 143 ? -17.292 -4.368  7.835  1.000 42.920  ? 1404 LEU AAA CB   1 
ATOM   2354 C CG   . LEU A 1 143 ? -17.670 -2.895  7.752  1.000 42.470  ? 1404 LEU AAA CG   1 
ATOM   2355 C CD1  . LEU A 1 143 ? -19.144 -2.672  8.051  1.000 42.470  ? 1404 LEU AAA CD1  1 
ATOM   2356 C CD2  . LEU A 1 143 ? -16.812 -2.060  8.699  1.000 45.510  ? 1404 LEU AAA CD2  1 
ATOM   2357 H H    . LEU A 1 143 ? -16.851 -4.527  5.342  1.000 52.890  ? 1404 LEU AAA H    1 
ATOM   2358 H HA   . LEU A 1 143 ? -15.292 -3.949  7.624  1.000 47.780  ? 1404 LEU AAA HA   1 
ATOM   2359 H HB2  . LEU A 1 143 ? -17.936 -4.908  7.335  1.000 42.920  ? 1404 LEU AAA HB2  1 
ATOM   2360 H HB3  . LEU A 1 143 ? -17.315 -4.668  8.765  1.000 42.920  ? 1404 LEU AAA HB3  1 
ATOM   2361 H HG   . LEU A 1 143 ? -17.497 -2.586  6.829  1.000 42.470  ? 1404 LEU AAA HG   1 
ATOM   2362 H HD11 . LEU A 1 143 ? -19.684 -3.163  7.407  1.000 42.470  ? 1404 LEU AAA HD11 1 
ATOM   2363 H HD12 . LEU A 1 143 ? -19.348 -1.723  7.990  1.000 42.470  ? 1404 LEU AAA HD12 1 
ATOM   2364 H HD13 . LEU A 1 143 ? -19.345 -2.988  8.949  1.000 42.470  ? 1404 LEU AAA HD13 1 
ATOM   2365 H HD21 . LEU A 1 143 ? -16.944 -2.367  9.613  1.000 45.510  ? 1404 LEU AAA HD21 1 
ATOM   2366 H HD22 . LEU A 1 143 ? -17.069 -1.124  8.630  1.000 45.510  ? 1404 LEU AAA HD22 1 
ATOM   2367 H HD23 . LEU A 1 143 ? -15.874 -2.157  8.458  1.000 45.510  ? 1404 LEU AAA HD23 1 
ATOM   2368 N N    . LYS A 1 144 ? -15.799 -7.120  7.046  1.000 50.630  ? 1405 LYS AAA N    1 
ATOM   2369 C CA   . LYS A 1 144 ? -15.243 -8.488  7.280  1.000 53.760  ? 1405 LYS AAA CA   1 
ATOM   2370 C C    . LYS A 1 144 ? -13.732 -8.504  7.041  1.000 56.890  ? 1405 LYS AAA C    1 
ATOM   2371 O O    . LYS A 1 144 ? -13.057 -9.232  7.746  1.000 56.480  ? 1405 LYS AAA O    1 
ATOM   2372 C CB   . LYS A 1 144 ? -15.887 -9.506  6.342  1.000 56.780  ? 1405 LYS AAA CB   1 
ATOM   2373 C CG   . LYS A 1 144 ? -15.240 -10.883 6.220  1.000 58.080  ? 1405 LYS AAA CG   1 
ATOM   2374 C CD   . LYS A 1 144 ? -15.996 -11.662 5.150  1.000 64.820  ? 1405 LYS AAA CD   1 
ATOM   2375 C CE   . LYS A 1 144 ? -15.396 -12.975 4.721  1.000 65.900  ? 1405 LYS AAA CE   1 
ATOM   2376 N NZ   . LYS A 1 144 ? -15.582 -13.965 5.798  1.000 74.270  ? 1405 LYS AAA NZ   1 
ATOM   2377 H H    . LYS A 1 144 ? -16.566 -7.004  6.399  1.000 50.630  ? 1405 LYS AAA H    1 
ATOM   2378 H HA   . LYS A 1 144 ? -15.408 -8.736  8.219  1.000 53.760  ? 1405 LYS AAA HA   1 
ATOM   2379 H HB2  . LYS A 1 144 ? -16.815 -9.647  6.625  1.000 56.780  ? 1405 LYS AAA HB2  1 
ATOM   2380 H HB3  . LYS A 1 144 ? -15.921 -9.122  5.441  1.000 56.780  ? 1405 LYS AAA HB3  1 
ATOM   2381 H HG2  . LYS A 1 144 ? -14.296 -10.765 5.980  1.000 58.080  ? 1405 LYS AAA HG2  1 
ATOM   2382 H HG3  . LYS A 1 144 ? -15.288 -11.330 7.092  1.000 58.080  ? 1405 LYS AAA HG3  1 
ATOM   2383 H HD2  . LYS A 1 144 ? -16.902 -11.852 5.473  1.000 64.820  ? 1405 LYS AAA HD2  1 
ATOM   2384 H HD3  . LYS A 1 144 ? -16.076 -11.106 4.346  1.000 64.820  ? 1405 LYS AAA HD3  1 
ATOM   2385 H HE2  . LYS A 1 144 ? -15.829 -13.280 3.901  1.000 65.900  ? 1405 LYS AAA HE2  1 
ATOM   2386 H HE3  . LYS A 1 144 ? -14.446 -12.854 4.531  1.000 65.900  ? 1405 LYS AAA HE3  1 
ATOM   2387 H HZ1  . LYS A 1 144 ? -15.174 -13.676 6.555  1.000 74.270  ? 1405 LYS AAA HZ1  1 
ATOM   2388 H HZ2  . LYS A 1 144 ? -15.226 -14.761 5.548  1.000 74.270  ? 1405 LYS AAA HZ2  1 
ATOM   2389 H HZ3  . LYS A 1 144 ? -16.467 -14.076 5.963  1.000 74.270  ? 1405 LYS AAA HZ3  1 
ATOM   2390 N N    . LYS A 1 145 ? -13.230 -7.733  6.076  1.000 60.470  ? 1406 LYS AAA N    1 
ATOM   2391 C CA   . LYS A 1 145 ? -11.782 -7.679  5.741  1.000 62.860  ? 1406 LYS AAA CA   1 
ATOM   2392 C C    . LYS A 1 145 ? -11.028 -6.893  6.818  1.000 48.750  ? 1406 LYS AAA C    1 
ATOM   2393 O O    . LYS A 1 145 ? -9.890  -7.239  7.028  1.000 44.970  ? 1406 LYS AAA O    1 
ATOM   2394 C CB   . LYS A 1 145 ? -11.496 -7.099  4.339  1.000 72.830  ? 1406 LYS AAA CB   1 
ATOM   2395 C CG   . LYS A 1 145 ? -11.964 -7.941  3.151  1.000 93.720  ? 1406 LYS AAA CG   1 
ATOM   2396 C CD   . LYS A 1 145 ? -12.508 -9.329  3.523  1.000 112.310 ? 1406 LYS AAA CD   1 
ATOM   2397 C CE   . LYS A 1 145 ? -13.039 -10.135 2.355  1.000 113.480 ? 1406 LYS AAA CE   1 
ATOM   2398 N NZ   . LYS A 1 145 ? -11.971 -10.990 1.784  1.000 112.630 ? 1406 LYS AAA NZ   1 
ATOM   2399 H H    . LYS A 1 145 ? -13.878 -7.161  5.553  1.000 60.470  ? 1406 LYS AAA H    1 
ATOM   2400 H HA   . LYS A 1 145 ? -11.431 -8.599  5.722  1.000 62.860  ? 1406 LYS AAA HA   1 
ATOM   2401 H HB2  . LYS A 1 145 ? -11.919 -6.217  4.274  1.000 72.830  ? 1406 LYS AAA HB2  1 
ATOM   2402 H HB3  . LYS A 1 145 ? -10.530 -6.957  4.251  1.000 72.830  ? 1406 LYS AAA HB3  1 
ATOM   2403 H HG2  . LYS A 1 145 ? -12.672 -7.452  2.681  1.000 93.720  ? 1406 LYS AAA HG2  1 
ATOM   2404 H HG3  . LYS A 1 145 ? -11.208 -8.064  2.538  1.000 93.720  ? 1406 LYS AAA HG3  1 
ATOM   2405 H HD2  . LYS A 1 145 ? -11.794 -9.848  3.951  1.000 112.310 ? 1406 LYS AAA HD2  1 
ATOM   2406 H HD3  . LYS A 1 145 ? -13.234 -9.224  4.175  1.000 112.310 ? 1406 LYS AAA HD3  1 
ATOM   2407 H HE2  . LYS A 1 145 ? -13.781 -10.694 2.654  1.000 113.480 ? 1406 LYS AAA HE2  1 
ATOM   2408 H HE3  . LYS A 1 145 ? -13.377 -9.531  1.667  1.000 113.480 ? 1406 LYS AAA HE3  1 
ATOM   2409 H HZ1  . LYS A 1 145 ? -11.284 -10.472 1.496  1.000 112.630 ? 1406 LYS AAA HZ1  1 
ATOM   2410 H HZ2  . LYS A 1 145 ? -12.301 -11.469 1.088  1.000 112.630 ? 1406 LYS AAA HZ2  1 
ATOM   2411 H HZ3  . LYS A 1 145 ? -11.664 -11.562 2.418  1.000 112.630 ? 1406 LYS AAA HZ3  1 
ATOM   2412 N N    . LYS A 1 146 ? -11.621 -5.875  7.453  1.000 56.890  ? 1407 LYS AAA N    1 
ATOM   2413 C CA   . LYS A 1 146 ? -11.021 -5.134  8.614  1.000 56.740  ? 1407 LYS AAA CA   1 
ATOM   2414 C C    . LYS A 1 146 ? -11.308 -5.824  9.970  1.000 53.870  ? 1407 LYS AAA C    1 
ATOM   2415 O O    . LYS A 1 146 ? -11.022 -5.221  11.031 1.000 55.580  ? 1407 LYS AAA O    1 
ATOM   2416 C CB   . LYS A 1 146 ? -11.565 -3.708  8.643  1.000 60.710  ? 1407 LYS AAA CB   1 
ATOM   2417 C CG   . LYS A 1 146 ? -11.298 -2.910  7.384  1.000 58.770  ? 1407 LYS AAA CG   1 
ATOM   2418 C CD   . LYS A 1 146 ? -10.111 -2.030  7.531  1.000 62.250  ? 1407 LYS AAA CD   1 
ATOM   2419 C CE   . LYS A 1 146 ? -9.884  -1.128  6.342  1.000 60.910  ? 1407 LYS AAA CE   1 
ATOM   2420 N NZ   . LYS A 1 146 ? -9.129  0.064   6.785  1.000 59.920  ? 1407 LYS AAA NZ   1 
ATOM   2421 H H    . LYS A 1 146 ? -12.532 -5.603  7.113  1.000 56.890  ? 1407 LYS AAA H    1 
ATOM   2422 H HA   . LYS A 1 146 ? -10.043 -5.112  8.499  1.000 56.740  ? 1407 LYS AAA HA   1 
ATOM   2423 H HB2  . LYS A 1 146 ? -12.532 -3.746  8.800  1.000 60.710  ? 1407 LYS AAA HB2  1 
ATOM   2424 H HB3  . LYS A 1 146 ? -11.172 -3.240  9.409  1.000 60.710  ? 1407 LYS AAA HB3  1 
ATOM   2425 H HG2  . LYS A 1 146 ? -11.154 -3.535  6.642  1.000 58.770  ? 1407 LYS AAA HG2  1 
ATOM   2426 H HG3  . LYS A 1 146 ? -12.089 -2.365  7.185  1.000 58.770  ? 1407 LYS AAA HG3  1 
ATOM   2427 H HD2  . LYS A 1 146 ? -10.222 -1.474  8.332  1.000 62.250  ? 1407 LYS AAA HD2  1 
ATOM   2428 H HD3  . LYS A 1 146 ? -9.314  -2.587  7.661  1.000 62.250  ? 1407 LYS AAA HD3  1 
ATOM   2429 H HE2  . LYS A 1 146 ? -9.387  -1.611  5.655  1.000 60.910  ? 1407 LYS AAA HE2  1 
ATOM   2430 H HE3  . LYS A 1 146 ? -10.744 -0.866  5.962  1.000 60.910  ? 1407 LYS AAA HE3  1 
ATOM   2431 H HZ1  . LYS A 1 146 ? -9.600  0.507   7.421  1.000 59.920  ? 1407 LYS AAA HZ1  1 
ATOM   2432 H HZ2  . LYS A 1 146 ? -8.983  0.615   6.079  1.000 59.920  ? 1407 LYS AAA HZ2  1 
ATOM   2433 H HZ3  . LYS A 1 146 ? -8.330  -0.190  7.132  1.000 59.920  ? 1407 LYS AAA HZ3  1 
ATOM   2434 N N    . LYS A 1 147 ? -11.840 -7.046  9.943  1.000 56.210  ? 1408 LYS AAA N    1 
ATOM   2435 C CA   . LYS A 1 147 ? -12.113 -7.879  11.138 1.000 61.140  ? 1408 LYS AAA CA   1 
ATOM   2436 C C    . LYS A 1 147 ? -13.103 -7.138  12.041 1.000 57.460  ? 1408 LYS AAA C    1 
ATOM   2437 O O    . LYS A 1 147 ? -12.897 -7.136  13.260 1.000 59.380  ? 1408 LYS AAA O    1 
ATOM   2438 C CB   . LYS A 1 147 ? -10.779 -8.193  11.815 1.000 66.590  ? 1408 LYS AAA CB   1 
ATOM   2439 C CG   . LYS A 1 147 ? -9.699  -8.708  10.876 1.000 76.760  ? 1408 LYS AAA CG   1 
ATOM   2440 C CD   . LYS A 1 147 ? -8.794  -9.751  11.483 1.000 84.770  ? 1408 LYS AAA CD   1 
ATOM   2441 C CE   . LYS A 1 147 ? -7.575  -10.035 10.632 1.000 92.760  ? 1408 LYS AAA CE   1 
ATOM   2442 N NZ   . LYS A 1 147 ? -6.610  -10.895 11.355 1.000 102.260 ? 1408 LYS AAA NZ   1 
ATOM   2443 H H    . LYS A 1 147 ? -12.129 -7.438  9.058  1.000 56.210  ? 1408 LYS AAA H    1 
ATOM   2444 H HA   . LYS A 1 147 ? -12.520 -8.726  10.842 1.000 61.140  ? 1408 LYS AAA HA   1 
ATOM   2445 H HB2  . LYS A 1 147 ? -10.456 -7.381  12.259 1.000 66.590  ? 1408 LYS AAA HB2  1 
ATOM   2446 H HB3  . LYS A 1 147 ? -10.935 -8.858  12.518 1.000 66.590  ? 1408 LYS AAA HB3  1 
ATOM   2447 H HG2  . LYS A 1 147 ? -10.131 -9.097  10.086 1.000 76.760  ? 1408 LYS AAA HG2  1 
ATOM   2448 H HG3  . LYS A 1 147 ? -9.146  -7.950  10.589 1.000 76.760  ? 1408 LYS AAA HG3  1 
ATOM   2449 H HD2  . LYS A 1 147 ? -8.502  -9.446  12.368 1.000 84.770  ? 1408 LYS AAA HD2  1 
ATOM   2450 H HD3  . LYS A 1 147 ? -9.300  -10.582 11.605 1.000 84.770  ? 1408 LYS AAA HD3  1 
ATOM   2451 H HE2  . LYS A 1 147 ? -7.848  -10.479 9.807  1.000 92.760  ? 1408 LYS AAA HE2  1 
ATOM   2452 H HE3  . LYS A 1 147 ? -7.141  -9.194  10.391 1.000 92.760  ? 1408 LYS AAA HE3  1 
ATOM   2453 H HZ1  . LYS A 1 147 ? -6.342  -10.482 12.117 1.000 102.260 ? 1408 LYS AAA HZ1  1 
ATOM   2454 H HZ2  . LYS A 1 147 ? -5.889  -11.056 10.829 1.000 102.260 ? 1408 LYS AAA HZ2  1 
ATOM   2455 H HZ3  . LYS A 1 147 ? -7.002  -11.684 11.569 1.000 102.260 ? 1408 LYS AAA HZ3  1 
ATOM   2456 N N    . VAL A 1 148 ? -14.113 -6.503  11.444 1.000 47.410  ? 1409 VAL AAA N    1 
ATOM   2457 C CA   . VAL A 1 148 ? -15.276 -5.913  12.161 1.000 44.940  ? 1409 VAL AAA CA   1 
ATOM   2458 C C    . VAL A 1 148 ? -16.419 -6.930  12.110 1.000 51.040  ? 1409 VAL AAA C    1 
ATOM   2459 O O    . VAL A 1 148 ? -16.809 -7.346  10.981 1.000 57.660  ? 1409 VAL AAA O    1 
ATOM   2460 C CB   . VAL A 1 148 ? -15.674 -4.561  11.561 1.000 42.580  ? 1409 VAL AAA CB   1 
ATOM   2461 C CG1  . VAL A 1 148 ? -16.841 -3.947  12.307 1.000 40.920  ? 1409 VAL AAA CG1  1 
ATOM   2462 C CG2  . VAL A 1 148 ? -14.494 -3.594  11.546 1.000 45.720  ? 1409 VAL AAA CG2  1 
ATOM   2463 H H    . VAL A 1 148 ? -14.066 -6.429  10.438 1.000 47.410  ? 1409 VAL AAA H    1 
ATOM   2464 H HA   . VAL A 1 148 ? -15.022 -5.767  13.090 1.000 44.940  ? 1409 VAL AAA HA   1 
ATOM   2465 H HB   . VAL A 1 148 ? -15.944 -4.724  10.624 1.000 42.580  ? 1409 VAL AAA HB   1 
ATOM   2466 H HG11 . VAL A 1 148 ? -17.608 -4.544  12.259 1.000 40.920  ? 1409 VAL AAA HG11 1 
ATOM   2467 H HG12 . VAL A 1 148 ? -17.070 -3.091  11.904 1.000 40.920  ? 1409 VAL AAA HG12 1 
ATOM   2468 H HG13 . VAL A 1 148 ? -16.596 -3.811  13.239 1.000 40.920  ? 1409 VAL AAA HG13 1 
ATOM   2469 H HG21 . VAL A 1 148 ? -14.181 -3.449  12.456 1.000 45.720  ? 1409 VAL AAA HG21 1 
ATOM   2470 H HG22 . VAL A 1 148 ? -14.774 -2.746  11.160 1.000 45.720  ? 1409 VAL AAA HG22 1 
ATOM   2471 H HG23 . VAL A 1 148 ? -13.773 -3.970  11.012 1.000 45.720  ? 1409 VAL AAA HG23 1 
ATOM   2472 N N    . ILE A 1 149 ? -16.887 -7.364  13.286 1.000 46.860  ? 1410 ILE AAA N    1 
ATOM   2473 C CA   . ILE A 1 149 ? -18.080 -8.250  13.442 1.000 43.320  ? 1410 ILE AAA CA   1 
ATOM   2474 C C    . ILE A 1 149 ? -19.309 -7.347  13.336 1.000 41.990  ? 1410 ILE AAA C    1 
ATOM   2475 O O    . ILE A 1 149 ? -19.334 -6.310  14.055 1.000 40.800  ? 1410 ILE AAA O    1 
ATOM   2476 C CB   . ILE A 1 149 ? -18.019 -9.038  14.758 1.000 41.010  ? 1410 ILE AAA CB   1 
ATOM   2477 C CG1  . ILE A 1 149 ? -16.767 -9.913  14.790 1.000 41.690  ? 1410 ILE AAA CG1  1 
ATOM   2478 C CG2  . ILE A 1 149 ? -19.276 -9.861  15.002 1.000 38.640  ? 1410 ILE AAA CG2  1 
ATOM   2479 C CD1  . ILE A 1 149 ? -16.379 -10.331 16.168 1.000 48.040  ? 1410 ILE AAA CD1  1 
ATOM   2480 H H    . ILE A 1 149 ? -16.387 -7.062  14.110 1.000 46.860  ? 1410 ILE AAA H    1 
ATOM   2481 H HA   . ILE A 1 149 ? -18.083 -8.893  12.710 1.000 43.320  ? 1410 ILE AAA HA   1 
ATOM   2482 H HB   . ILE A 1 149 ? -17.960 -8.380  15.494 1.000 41.010  ? 1410 ILE AAA HB   1 
ATOM   2483 H HG12 . ILE A 1 149 ? -16.928 -10.712 14.245 1.000 41.690  ? 1410 ILE AAA HG12 1 
ATOM   2484 H HG13 . ILE A 1 149 ? -16.025 -9.416  14.384 1.000 41.690  ? 1410 ILE AAA HG13 1 
ATOM   2485 H HG21 . ILE A 1 149 ? -20.050 -9.272  15.045 1.000 38.640  ? 1410 ILE AAA HG21 1 
ATOM   2486 H HG22 . ILE A 1 149 ? -19.195 -10.340 15.845 1.000 38.640  ? 1410 ILE AAA HG22 1 
ATOM   2487 H HG23 . ILE A 1 149 ? -19.395 -10.499 14.277 1.000 38.640  ? 1410 ILE AAA HG23 1 
ATOM   2488 H HD11 . ILE A 1 149 ? -16.200 -9.543  16.709 1.000 48.040  ? 1410 ILE AAA HD11 1 
ATOM   2489 H HD12 . ILE A 1 149 ? -15.579 -10.883 16.128 1.000 48.040  ? 1410 ILE AAA HD12 1 
ATOM   2490 H HD13 . ILE A 1 149 ? -17.104 -10.841 16.570 1.000 48.040  ? 1410 ILE AAA HD13 1 
ATOM   2491 N N    . VAL A 1 150 ? -20.222 -7.672  12.408 1.000 37.760  ? 1411 VAL AAA N    1 
ATOM   2492 C CA   . VAL A 1 150 ? -21.512 -6.948  12.257 1.000 40.300  ? 1411 VAL AAA CA   1 
ATOM   2493 C C    . VAL A 1 150 ? -22.580 -7.810  12.914 1.000 41.470  ? 1411 VAL AAA C    1 
ATOM   2494 O O    . VAL A 1 150 ? -22.710 -8.980  12.510 1.000 42.490  ? 1411 VAL AAA O    1 
ATOM   2495 C CB   . VAL A 1 150 ? -21.841 -6.640  10.790 1.000 43.840  ? 1411 VAL AAA CB   1 
ATOM   2496 C CG1  . VAL A 1 150 ? -23.149 -5.857  10.668 1.000 40.370  ? 1411 VAL AAA CG1  1 
ATOM   2497 C CG2  . VAL A 1 150 ? -20.674 -5.921  10.109 1.000 42.920  ? 1411 VAL AAA CG2  1 
ATOM   2498 H H    . VAL A 1 150 ? -20.015 -8.443  11.790 1.000 37.760  ? 1411 VAL AAA H    1 
ATOM   2499 H HA   . VAL A 1 150 ? -21.445 -6.099  12.729 1.000 40.300  ? 1411 VAL AAA HA   1 
ATOM   2500 H HB   . VAL A 1 150 ? -21.976 -7.506  10.332 1.000 43.840  ? 1411 VAL AAA HB   1 
ATOM   2501 H HG11 . VAL A 1 150 ? -23.877 -6.380  11.046 1.000 40.370  ? 1411 VAL AAA HG11 1 
ATOM   2502 H HG12 . VAL A 1 150 ? -23.333 -5.675  9.730  1.000 40.370  ? 1411 VAL AAA HG12 1 
ATOM   2503 H HG13 . VAL A 1 150 ? -23.070 -5.016  11.151 1.000 40.370  ? 1411 VAL AAA HG13 1 
ATOM   2504 H HG21 . VAL A 1 150 ? -20.493 -5.084  10.572 1.000 42.920  ? 1411 VAL AAA HG21 1 
ATOM   2505 H HG22 . VAL A 1 150 ? -20.903 -5.736  9.182  1.000 42.920  ? 1411 VAL AAA HG22 1 
ATOM   2506 H HG23 . VAL A 1 150 ? -19.882 -6.485  10.140 1.000 42.920  ? 1411 VAL AAA HG23 1 
ATOM   2507 N N    . ILE A 1 151 ? -23.243 -7.256  13.927 1.000 39.990  ? 1412 ILE AAA N    1 
ATOM   2508 C CA   . ILE A 1 151 ? -24.339 -7.906  14.692 1.000 40.410  ? 1412 ILE AAA CA   1 
ATOM   2509 C C    . ILE A 1 151 ? -25.587 -7.098  14.392 1.000 41.220  ? 1412 ILE AAA C    1 
ATOM   2510 O O    . ILE A 1 151 ? -25.768 -6.014  14.944 1.000 41.200  ? 1412 ILE AAA O    1 
ATOM   2511 C CB   . ILE A 1 151 ? -24.016 -7.929  16.199 1.000 42.800  ? 1412 ILE AAA CB   1 
ATOM   2512 C CG1  . ILE A 1 151 ? -22.653 -8.563  16.503 1.000 45.200  ? 1412 ILE AAA CG1  1 
ATOM   2513 C CG2  . ILE A 1 151 ? -25.134 -8.580  16.991 1.000 41.960  ? 1412 ILE AAA CG2  1 
ATOM   2514 C CD1  . ILE A 1 151 ? -22.555 -10.028 16.174 1.000 45.950  ? 1412 ILE AAA CD1  1 
ATOM   2515 H H    . ILE A 1 151 ? -22.958 -6.319  14.174 1.000 39.990  ? 1412 ILE AAA H    1 
ATOM   2516 H HA   . ILE A 1 151 ? -24.446 -8.816  14.362 1.000 40.410  ? 1412 ILE AAA HA   1 
ATOM   2517 H HB   . ILE A 1 151 ? -23.948 -6.990  16.501 1.000 42.800  ? 1412 ILE AAA HB   1 
ATOM   2518 H HG12 . ILE A 1 151 ? -21.963 -8.085  15.994 1.000 45.200  ? 1412 ILE AAA HG12 1 
ATOM   2519 H HG13 . ILE A 1 151 ? -22.458 -8.447  17.457 1.000 45.200  ? 1412 ILE AAA HG13 1 
ATOM   2520 H HG21 . ILE A 1 151 ? -25.960 -8.081  16.862 1.000 41.960  ? 1412 ILE AAA HG21 1 
ATOM   2521 H HG22 . ILE A 1 151 ? -24.908 -8.580  17.937 1.000 41.960  ? 1412 ILE AAA HG22 1 
ATOM   2522 H HG23 . ILE A 1 151 ? -25.259 -9.496  16.688 1.000 41.960  ? 1412 ILE AAA HG23 1 
ATOM   2523 H HD11 . ILE A 1 151 ? -23.216 -10.523 16.689 1.000 45.950  ? 1412 ILE AAA HD11 1 
ATOM   2524 H HD12 . ILE A 1 151 ? -21.665 -10.353 16.395 1.000 45.950  ? 1412 ILE AAA HD12 1 
ATOM   2525 H HD13 . ILE A 1 151 ? -22.721 -10.161 15.224 1.000 45.950  ? 1412 ILE AAA HD13 1 
ATOM   2526 N N    . PRO A 1 152 ? -26.426 -7.558  13.438 1.000 48.220  ? 1413 PRO AAA N    1 
ATOM   2527 C CA   . PRO A 1 152 ? -27.677 -6.872  13.145 1.000 46.770  ? 1413 PRO AAA CA   1 
ATOM   2528 C C    . PRO A 1 152 ? -28.701 -7.262  14.212 1.000 46.350  ? 1413 PRO AAA C    1 
ATOM   2529 O O    . PRO A 1 152 ? -28.766 -8.417  14.560 1.000 50.480  ? 1413 PRO AAA O    1 
ATOM   2530 C CB   . PRO A 1 152 ? -28.013 -7.343  11.726 1.000 49.920  ? 1413 PRO AAA CB   1 
ATOM   2531 C CG   . PRO A 1 152 ? -27.325 -8.688  11.574 1.000 48.580  ? 1413 PRO AAA CG   1 
ATOM   2532 C CD   . PRO A 1 152 ? -26.191 -8.716  12.560 1.000 45.970  ? 1413 PRO AAA CD   1 
ATOM   2533 H HA   . PRO A 1 152 ? -27.519 -5.895  13.132 1.000 46.770  ? 1413 PRO AAA HA   1 
ATOM   2534 H HB2  . PRO A 1 152 ? -28.981 -7.432  11.605 1.000 49.920  ? 1413 PRO AAA HB2  1 
ATOM   2535 H HB3  . PRO A 1 152 ? -27.684 -6.707  11.057 1.000 49.920  ? 1413 PRO AAA HB3  1 
ATOM   2536 H HG2  . PRO A 1 152 ? -27.948 -9.422  11.758 1.000 48.580  ? 1413 PRO AAA HG2  1 
ATOM   2537 H HG3  . PRO A 1 152 ? -26.981 -8.803  10.664 1.000 48.580  ? 1413 PRO AAA HG3  1 
ATOM   2538 H HD2  . PRO A 1 152 ? -26.193 -9.552  13.071 1.000 45.970  ? 1413 PRO AAA HD2  1 
ATOM   2539 H HD3  . PRO A 1 152 ? -25.328 -8.642  12.102 1.000 45.970  ? 1413 PRO AAA HD3  1 
ATOM   2540 N N    . VAL A 1 153 ? -29.398 -6.266  14.741 1.000 44.930  ? 1414 VAL AAA N    1 
ATOM   2541 C CA   . VAL A 1 153 ? -30.571 -6.397  15.653 1.000 41.910  ? 1414 VAL AAA CA   1 
ATOM   2542 C C    . VAL A 1 153 ? -31.790 -5.836  14.883 1.000 44.090  ? 1414 VAL AAA C    1 
ATOM   2543 O O    . VAL A 1 153 ? -31.905 -4.622  14.698 1.000 43.000  ? 1414 VAL AAA O    1 
ATOM   2544 C CB   . VAL A 1 153 ? -30.301 -5.668  16.991 1.000 45.710  ? 1414 VAL AAA CB   1 
ATOM   2545 C CG1  . VAL A 1 153 ? -31.414 -5.856  18.004 1.000 46.680  ? 1414 VAL AAA CG1  1 
ATOM   2546 C CG2  . VAL A 1 153 ? -28.973 -6.054  17.645 1.000 47.950  ? 1414 VAL AAA CG2  1 
ATOM   2547 H H    . VAL A 1 153 ? -29.077 -5.344  14.481 1.000 44.930  ? 1414 VAL AAA H    1 
ATOM   2548 H HA   . VAL A 1 153 ? -30.710 -7.343  15.841 1.000 41.910  ? 1414 VAL AAA HA   1 
ATOM   2549 H HB   . VAL A 1 153 ? -30.249 -4.700  16.793 1.000 45.710  ? 1414 VAL AAA HB   1 
ATOM   2550 H HG11 . VAL A 1 153 ? -32.247 -5.507  17.640 1.000 46.680  ? 1414 VAL AAA HG11 1 
ATOM   2551 H HG12 . VAL A 1 153 ? -31.192 -5.379  18.823 1.000 46.680  ? 1414 VAL AAA HG12 1 
ATOM   2552 H HG13 . VAL A 1 153 ? -31.518 -6.803  18.200 1.000 46.680  ? 1414 VAL AAA HG13 1 
ATOM   2553 H HG21 . VAL A 1 153 ? -28.967 -7.009  17.829 1.000 47.950  ? 1414 VAL AAA HG21 1 
ATOM   2554 H HG22 . VAL A 1 153 ? -28.866 -5.562  18.478 1.000 47.950  ? 1414 VAL AAA HG22 1 
ATOM   2555 H HG23 . VAL A 1 153 ? -28.239 -5.836  17.044 1.000 47.950  ? 1414 VAL AAA HG23 1 
ATOM   2556 N N    . GLY A 1 154 ? -32.640 -6.691  14.327 1.000 44.910  ? 1415 GLY AAA N    1 
ATOM   2557 C CA   . GLY A 1 154 ? -33.893 -6.231  13.704 1.000 44.680  ? 1415 GLY AAA CA   1 
ATOM   2558 C C    . GLY A 1 154 ? -34.926 -5.974  14.776 1.000 46.990  ? 1415 GLY AAA C    1 
ATOM   2559 O O    . GLY A 1 154 ? -35.153 -6.875  15.599 1.000 51.260  ? 1415 GLY AAA O    1 
ATOM   2560 H H    . GLY A 1 154 ? -32.425 -7.678  14.330 1.000 44.910  ? 1415 GLY AAA H    1 
ATOM   2561 H HA2  . GLY A 1 154 ? -33.714 -5.404  13.189 1.000 44.680  ? 1415 GLY AAA HA2  1 
ATOM   2562 H HA3  . GLY A 1 154 ? -34.213 -6.923  13.072 1.000 44.680  ? 1415 GLY AAA HA3  1 
ATOM   2563 N N    . ILE A 1 155 ? -35.442 -4.756  14.824 1.000 43.700  ? 1416 ILE AAA N    1 
ATOM   2564 C CA   . ILE A 1 155 ? -36.488 -4.322  15.785 1.000 51.480  ? 1416 ILE AAA CA   1 
ATOM   2565 C C    . ILE A 1 155 ? -37.791 -4.113  15.015 1.000 57.810  ? 1416 ILE AAA C    1 
ATOM   2566 O O    . ILE A 1 155 ? -37.875 -3.153  14.225 1.000 56.630  ? 1416 ILE AAA O    1 
ATOM   2567 C CB   . ILE A 1 155 ? -36.072 -3.030  16.505 1.000 47.540  ? 1416 ILE AAA CB   1 
ATOM   2568 C CG1  . ILE A 1 155 ? -34.691 -3.139  17.158 1.000 46.480  ? 1416 ILE AAA CG1  1 
ATOM   2569 C CG2  . ILE A 1 155 ? -37.144 -2.662  17.509 1.000 47.280  ? 1416 ILE AAA CG2  1 
ATOM   2570 C CD1  . ILE A 1 155 ? -34.087 -1.792  17.470 1.000 44.360  ? 1416 ILE AAA CD1  1 
ATOM   2571 H H    . ILE A 1 155 ? -35.085 -4.092  14.152 1.000 43.700  ? 1416 ILE AAA H    1 
ATOM   2572 H HA   . ILE A 1 155 ? -36.620 -5.033  16.437 1.000 51.480  ? 1416 ILE AAA HA   1 
ATOM   2573 H HB   . ILE A 1 155 ? -36.022 -2.315  15.824 1.000 47.540  ? 1416 ILE AAA HB   1 
ATOM   2574 H HG12 . ILE A 1 155 ? -34.775 -3.658  17.986 1.000 46.480  ? 1416 ILE AAA HG12 1 
ATOM   2575 H HG13 . ILE A 1 155 ? -34.095 -3.631  16.554 1.000 46.480  ? 1416 ILE AAA HG13 1 
ATOM   2576 H HG21 . ILE A 1 155 ? -37.989 -2.520  17.048 1.000 47.280  ? 1416 ILE AAA HG21 1 
ATOM   2577 H HG22 . ILE A 1 155 ? -36.893 -1.843  17.970 1.000 47.280  ? 1416 ILE AAA HG22 1 
ATOM   2578 H HG23 . ILE A 1 155 ? -37.246 -3.380  18.157 1.000 47.280  ? 1416 ILE AAA HG23 1 
ATOM   2579 H HD11 . ILE A 1 155 ? -33.988 -1.281  16.648 1.000 44.360  ? 1416 ILE AAA HD11 1 
ATOM   2580 H HD12 . ILE A 1 155 ? -33.214 -1.914  17.882 1.000 44.360  ? 1416 ILE AAA HD12 1 
ATOM   2581 H HD13 . ILE A 1 155 ? -34.668 -1.308  18.082 1.000 44.360  ? 1416 ILE AAA HD13 1 
ATOM   2582 N N    . GLY A 1 156 ? -38.789 -4.952  15.241 1.000 56.110  ? 1417 GLY AAA N    1 
ATOM   2583 C CA   . GLY A 1 156 ? -40.111 -4.675  14.665 1.000 65.050  ? 1417 GLY AAA CA   1 
ATOM   2584 C C    . GLY A 1 156 ? -40.311 -5.271  13.273 1.000 63.690  ? 1417 GLY AAA C    1 
ATOM   2585 O O    . GLY A 1 156 ? -39.406 -5.865  12.671 1.000 53.080  ? 1417 GLY AAA O    1 
ATOM   2586 H H    . GLY A 1 156 ? -38.661 -5.781  15.803 1.000 56.110  ? 1417 GLY AAA H    1 
ATOM   2587 H HA2  . GLY A 1 156 ? -40.808 -5.041  15.265 1.000 65.050  ? 1417 GLY AAA HA2  1 
ATOM   2588 H HA3  . GLY A 1 156 ? -40.239 -3.695  14.607 1.000 65.050  ? 1417 GLY AAA HA3  1 
ATOM   2589 N N    . PRO A 1 157 ? -41.573 -5.214  12.788 1.000 60.850  ? 1418 PRO AAA N    1 
ATOM   2590 C CA   . PRO A 1 157 ? -41.974 -5.972  11.608 1.000 64.390  ? 1418 PRO AAA CA   1 
ATOM   2591 C C    . PRO A 1 157 ? -41.485 -5.333  10.298 1.000 56.760  ? 1418 PRO AAA C    1 
ATOM   2592 O O    . PRO A 1 157 ? -41.375 -6.075  9.358  1.000 54.420  ? 1418 PRO AAA O    1 
ATOM   2593 C CB   . PRO A 1 157 ? -43.500 -6.017  11.743 1.000 62.200  ? 1418 PRO AAA CB   1 
ATOM   2594 C CG   . PRO A 1 157 ? -43.854 -4.755  12.480 1.000 59.590  ? 1418 PRO AAA CG   1 
ATOM   2595 C CD   . PRO A 1 157 ? -42.696 -4.497  13.415 1.000 57.900  ? 1418 PRO AAA CD   1 
ATOM   2596 H HA   . PRO A 1 157 ? -41.620 -6.894  11.675 1.000 64.390  ? 1418 PRO AAA HA   1 
ATOM   2597 H HB2  . PRO A 1 157 ? -43.930 -6.045  10.863 1.000 62.200  ? 1418 PRO AAA HB2  1 
ATOM   2598 H HB3  . PRO A 1 157 ? -43.785 -6.810  12.243 1.000 62.200  ? 1418 PRO AAA HB3  1 
ATOM   2599 H HG2  . PRO A 1 157 ? -43.972 -4.008  11.857 1.000 59.590  ? 1418 PRO AAA HG2  1 
ATOM   2600 H HG3  . PRO A 1 157 ? -44.689 -4.866  12.981 1.000 59.590  ? 1418 PRO AAA HG3  1 
ATOM   2601 H HD2  . PRO A 1 157 ? -42.515 -3.537  13.490 1.000 57.900  ? 1418 PRO AAA HD2  1 
ATOM   2602 H HD3  . PRO A 1 157 ? -42.889 -4.841  14.312 1.000 57.900  ? 1418 PRO AAA HD3  1 
ATOM   2603 N N    . HIS A 1 158 ? -41.089 -4.051  10.316 1.000 51.940  ? 1419 HIS AAA N    1 
ATOM   2604 C CA   . HIS A 1 158 ? -40.538 -3.295  9.156  1.000 52.850  ? 1419 HIS AAA CA   1 
ATOM   2605 C C    . HIS A 1 158 ? -39.007 -3.445  8.985  1.000 54.850  ? 1419 HIS AAA C    1 
ATOM   2606 O O    . HIS A 1 158 ? -38.527 -3.133  7.901  1.000 56.410  ? 1419 HIS AAA O    1 
ATOM   2607 C CB   . HIS A 1 158 ? -40.958 -1.832  9.283  1.000 56.430  ? 1419 HIS AAA CB   1 
ATOM   2608 C CG   . HIS A 1 158 ? -42.430 -1.682  9.454  1.000 63.150  ? 1419 HIS AAA CG   1 
ATOM   2609 N ND1  . HIS A 1 158 ? -43.319 -2.044  8.461  1.000 62.680  ? 1419 HIS AAA ND1  1 
ATOM   2610 C CD2  . HIS A 1 158 ? -43.167 -1.249  10.495 1.000 64.480  ? 1419 HIS AAA CD2  1 
ATOM   2611 C CE1  . HIS A 1 158 ? -44.541 -1.822  8.880  1.000 67.380  ? 1419 HIS AAA CE1  1 
ATOM   2612 N NE2  . HIS A 1 158 ? -44.476 -1.341  10.125 1.000 71.920  ? 1419 HIS AAA NE2  1 
ATOM   2613 H H    . HIS A 1 158 ? -41.185 -3.585  11.207 1.000 51.940  ? 1419 HIS AAA H    1 
ATOM   2614 H HA   . HIS A 1 158 ? -40.946 -3.656  8.334  1.000 52.850  ? 1419 HIS AAA HA   1 
ATOM   2615 H HB2  . HIS A 1 158 ? -40.495 -1.436  10.055 1.000 56.430  ? 1419 HIS AAA HB2  1 
ATOM   2616 H HB3  . HIS A 1 158 ? -40.670 -1.349  8.477  1.000 56.430  ? 1419 HIS AAA HB3  1 
ATOM   2617 H HD1  . HIS A 1 158 ? -43.100 -2.378  7.681  0.000 62.680  ? 1419 HIS AAA HD1  1 
ATOM   2618 H HD2  . HIS A 1 158 ? -42.847 -0.940  11.322 1.000 64.480  ? 1419 HIS AAA HD2  1 
ATOM   2619 H HE1  . HIS A 1 158 ? -45.329 -1.986  8.390  1.000 67.380  ? 1419 HIS AAA HE1  1 
ATOM   2620 H HE2  . HIS A 1 158 ? -45.164 -1.115  10.620 0.000 71.920  ? 1419 HIS AAA HE2  1 
ATOM   2621 N N    . ALA A 1 159 ? -38.245 -3.873  9.996  1.000 52.260  ? 1420 ALA AAA N    1 
ATOM   2622 C CA   . ALA A 1 159 ? -36.803 -4.191  9.866  1.000 50.280  ? 1420 ALA AAA CA   1 
ATOM   2623 C C    . ALA A 1 159 ? -36.582 -5.086  8.639  1.000 51.110  ? 1420 ALA AAA C    1 
ATOM   2624 O O    . ALA A 1 159 ? -37.396 -5.967  8.435  1.000 54.340  ? 1420 ALA AAA O    1 
ATOM   2625 C CB   . ALA A 1 159 ? -36.319 -4.882  11.116 1.000 49.380  ? 1420 ALA AAA CB   1 
ATOM   2626 H H    . ALA A 1 159 ? -38.694 -3.981  10.894 1.000 52.260  ? 1420 ALA AAA H    1 
ATOM   2627 H HA   . ALA A 1 159 ? -36.307 -3.349  9.734  1.000 50.280  ? 1420 ALA AAA HA   1 
ATOM   2628 H HB1  . ALA A 1 159 ? -35.375 -5.089  11.028 1.000 49.380  ? 1420 ALA AAA HB1  1 
ATOM   2629 H HB2  . ALA A 1 159 ? -36.451 -4.300  11.881 1.000 49.380  ? 1420 ALA AAA HB2  1 
ATOM   2630 H HB3  . ALA A 1 159 ? -36.819 -5.705  11.247 1.000 49.380  ? 1420 ALA AAA HB3  1 
ATOM   2631 N N    . ASN A 1 160 ? -35.489 -4.904  7.894  1.000 47.870  ? 1421 ASN AAA N    1 
ATOM   2632 C CA   . ASN A 1 160 ? -35.211 -5.603  6.617  1.000 46.150  ? 1421 ASN AAA CA   1 
ATOM   2633 C C    . ASN A 1 160 ? -34.512 -6.950  6.875  1.000 51.160  ? 1421 ASN AAA C    1 
ATOM   2634 O O    . ASN A 1 160 ? -33.261 -6.991  6.932  1.000 51.280  ? 1421 ASN AAA O    1 
ATOM   2635 C CB   . ASN A 1 160 ? -34.435 -4.679  5.690  1.000 44.330  ? 1421 ASN AAA CB   1 
ATOM   2636 C CG   . ASN A 1 160 ? -34.044 -5.329  4.378  1.000 49.160  ? 1421 ASN AAA CG   1 
ATOM   2637 O OD1  . ASN A 1 160 ? -34.204 -6.527  4.155  1.000 49.450  ? 1421 ASN AAA OD1  1 
ATOM   2638 N ND2  . ASN A 1 160 ? -33.468 -4.532  3.507  1.000 47.690  ? 1421 ASN AAA ND2  1 
ATOM   2639 H H    . ASN A 1 160 ? -34.818 -4.237  8.247  1.000 47.870  ? 1421 ASN AAA H    1 
ATOM   2640 H HA   . ASN A 1 160 ? -36.069 -5.784  6.166  1.000 46.150  ? 1421 ASN AAA HA   1 
ATOM   2641 H HB2  . ASN A 1 160 ? -34.981 -3.889  5.500  1.000 44.330  ? 1421 ASN AAA HB2  1 
ATOM   2642 H HB3  . ASN A 1 160 ? -33.623 -4.379  6.148  1.000 44.330  ? 1421 ASN AAA HB3  1 
ATOM   2643 H HD21 . ASN A 1 160 ? -33.214 -4.846  2.721  0.000 47.690  ? 1421 ASN AAA HD21 1 
ATOM   2644 H HD22 . ASN A 1 160 ? -33.334 -3.681  3.707  0.000 47.690  ? 1421 ASN AAA HD22 1 
ATOM   2645 N N    . LEU A 1 161 ? -35.295 -8.030  6.958  1.000 50.920  ? 1422 LEU AAA N    1 
ATOM   2646 C CA   . LEU A 1 161 ? -34.821 -9.396  7.297  1.000 46.180  ? 1422 LEU AAA CA   1 
ATOM   2647 C C    . LEU A 1 161 ? -33.924 -9.907  6.170  1.000 50.550  ? 1422 LEU AAA C    1 
ATOM   2648 O O    . LEU A 1 161 ? -33.040 -10.749 6.436  1.000 47.700  ? 1422 LEU AAA O    1 
ATOM   2649 C CB   . LEU A 1 161 ? -36.036 -10.309 7.501  1.000 47.330  ? 1422 LEU AAA CB   1 
ATOM   2650 C CG   . LEU A 1 161 ? -35.749 -11.720 8.027  1.000 48.390  ? 1422 LEU AAA CG   1 
ATOM   2651 C CD1  . LEU A 1 161 ? -35.066 -11.674 9.381  1.000 53.310  ? 1422 LEU AAA CD1  1 
ATOM   2652 C CD2  . LEU A 1 161 ? -37.021 -12.546 8.144  1.000 45.250  ? 1422 LEU AAA CD2  1 
ATOM   2653 H H    . LEU A 1 161 ? -36.277 -7.881  6.772  1.000 50.920  ? 1422 LEU AAA H    1 
ATOM   2654 H HA   . LEU A 1 161 ? -34.293 -9.346  8.127  1.000 46.180  ? 1422 LEU AAA HA   1 
ATOM   2655 H HB2  . LEU A 1 161 ? -36.647 -9.872  8.127  1.000 47.330  ? 1422 LEU AAA HB2  1 
ATOM   2656 H HB3  . LEU A 1 161 ? -36.503 -10.395 6.646  1.000 47.330  ? 1422 LEU AAA HB3  1 
ATOM   2657 H HG   . LEU A 1 161 ? -35.155 -12.174 7.379  1.000 48.390  ? 1422 LEU AAA HG   1 
ATOM   2658 H HD11 . LEU A 1 161 ? -34.223 -11.194 9.303  1.000 53.310  ? 1422 LEU AAA HD11 1 
ATOM   2659 H HD12 . LEU A 1 161 ? -34.897 -12.581 9.690  1.000 53.310  ? 1422 LEU AAA HD12 1 
ATOM   2660 H HD13 . LEU A 1 161 ? -35.641 -11.217 10.019 1.000 53.310  ? 1422 LEU AAA HD13 1 
ATOM   2661 H HD21 . LEU A 1 161 ? -37.637 -12.109 8.758  1.000 45.250  ? 1422 LEU AAA HD21 1 
ATOM   2662 H HD22 . LEU A 1 161 ? -36.802 -13.433 8.479  1.000 45.250  ? 1422 LEU AAA HD22 1 
ATOM   2663 H HD23 . LEU A 1 161 ? -37.439 -12.625 7.269  1.000 45.250  ? 1422 LEU AAA HD23 1 
ATOM   2664 N N    . LYS A 1 162 ? -34.149 -9.458  4.937  1.000 53.720  ? 1423 LYS AAA N    1 
ATOM   2665 C CA   . LYS A 1 162 ? -33.366 -9.947  3.764  1.000 55.580  ? 1423 LYS AAA CA   1 
ATOM   2666 C C    . LYS A 1 162 ? -31.905 -9.561  3.991  1.000 49.210  ? 1423 LYS AAA C    1 
ATOM   2667 O O    . LYS A 1 162 ? -31.019 -10.450 3.924  1.000 46.230  ? 1423 LYS AAA O    1 
ATOM   2668 C CB   . LYS A 1 162 ? -33.970 -9.365  2.487  1.000 62.920  ? 1423 LYS AAA CB   1 
ATOM   2669 C CG   . LYS A 1 162 ? -33.449 -9.902  1.168  1.000 64.060  ? 1423 LYS AAA CG   1 
ATOM   2670 C CD   . LYS A 1 162 ? -34.203 -9.229  0.029  1.000 70.050  ? 1423 LYS AAA CD   1 
ATOM   2671 C CE   . LYS A 1 162 ? -33.909 -9.830  -1.324 1.000 73.660  ? 1423 LYS AAA CE   1 
ATOM   2672 N NZ   . LYS A 1 162 ? -32.446 -9.937  -1.532 1.000 78.410  ? 1423 LYS AAA NZ   1 
ATOM   2673 H H    . LYS A 1 162 ? -34.871 -8.766  4.793  1.000 53.720  ? 1423 LYS AAA H    1 
ATOM   2674 H HA   . LYS A 1 162 ? -33.446 -10.928 3.722  1.000 55.580  ? 1423 LYS AAA HA   1 
ATOM   2675 H HB2  . LYS A 1 162 ? -34.939 -9.511  2.506  1.000 62.920  ? 1423 LYS AAA HB2  1 
ATOM   2676 H HB3  . LYS A 1 162 ? -33.830 -8.395  2.490  1.000 62.920  ? 1423 LYS AAA HB3  1 
ATOM   2677 H HG2  . LYS A 1 162 ? -32.487 -9.716  1.112  1.000 64.060  ? 1423 LYS AAA HG2  1 
ATOM   2678 H HG3  . LYS A 1 162 ? -33.581 -10.874 1.152  1.000 64.060  ? 1423 LYS AAA HG3  1 
ATOM   2679 H HD2  . LYS A 1 162 ? -35.167 -9.296  0.200  1.000 70.050  ? 1423 LYS AAA HD2  1 
ATOM   2680 H HD3  . LYS A 1 162 ? -33.968 -8.277  0.008  1.000 70.050  ? 1423 LYS AAA HD3  1 
ATOM   2681 H HE2  . LYS A 1 162 ? -34.316 -10.715 -1.384 1.000 73.660  ? 1423 LYS AAA HE2  1 
ATOM   2682 H HE3  . LYS A 1 162 ? -34.301 -9.272  -2.022 1.000 73.660  ? 1423 LYS AAA HE3  1 
ATOM   2683 H HZ1  . LYS A 1 162 ? -32.068 -9.114  -1.486 1.000 78.410  ? 1423 LYS AAA HZ1  1 
ATOM   2684 H HZ2  . LYS A 1 162 ? -32.278 -10.301 -2.345 1.000 78.410  ? 1423 LYS AAA HZ2  1 
ATOM   2685 H HZ3  . LYS A 1 162 ? -32.083 -10.465 -0.891 1.000 78.410  ? 1423 LYS AAA HZ3  1 
ATOM   2686 N N    . GLN A 1 163 ? -31.709 -8.299  4.373  1.000 50.820  ? 1424 GLN AAA N    1 
ATOM   2687 C CA   . GLN A 1 163 ? -30.377 -7.688  4.654  1.000 53.460  ? 1424 GLN AAA CA   1 
ATOM   2688 C C    . GLN A 1 163 ? -29.737 -8.335  5.887  1.000 54.610  ? 1424 GLN AAA C    1 
ATOM   2689 O O    . GLN A 1 163 ? -28.553 -8.663  5.784  1.000 57.830  ? 1424 GLN AAA O    1 
ATOM   2690 C CB   . GLN A 1 163 ? -30.478 -6.165  4.810  1.000 50.710  ? 1424 GLN AAA CB   1 
ATOM   2691 C CG   . GLN A 1 163 ? -30.341 -5.402  3.488  1.000 42.980  ? 1424 GLN AAA CG   1 
ATOM   2692 C CD   . GLN A 1 163 ? -30.130 -3.908  3.616  1.000 45.470  ? 1424 GLN AAA CD   1 
ATOM   2693 O OE1  . GLN A 1 163 ? -30.300 -3.290  4.675  1.000 38.550  ? 1424 GLN AAA OE1  1 
ATOM   2694 N NE2  . GLN A 1 163 ? -29.766 -3.295  2.496  1.000 46.770  ? 1424 GLN AAA NE2  1 
ATOM   2695 H H    . GLN A 1 163 ? -32.541 -7.734  4.473  1.000 50.820  ? 1424 GLN AAA H    1 
ATOM   2696 H HA   . GLN A 1 163 ? -29.789 -7.852  3.881  1.000 53.460  ? 1424 GLN AAA HA   1 
ATOM   2697 H HB2  . GLN A 1 163 ? -31.344 -5.950  5.216  1.000 50.710  ? 1424 GLN AAA HB2  1 
ATOM   2698 H HB3  . GLN A 1 163 ? -29.776 -5.868  5.426  1.000 50.710  ? 1424 GLN AAA HB3  1 
ATOM   2699 H HG2  . GLN A 1 163 ? -29.580 -5.763  2.984  1.000 42.980  ? 1424 GLN AAA HG2  1 
ATOM   2700 H HG3  . GLN A 1 163 ? -31.151 -5.538  2.951  1.000 42.980  ? 1424 GLN AAA HG3  1 
ATOM   2701 H HE21 . GLN A 1 163 ? -29.625 -2.422  2.495  0.000 46.770  ? 1424 GLN AAA HE21 1 
ATOM   2702 H HE22 . GLN A 1 163 ? -29.665 -3.759  1.751  0.000 46.770  ? 1424 GLN AAA HE22 1 
ATOM   2703 N N    . ILE A 1 164 ? -30.484 -8.515  6.991  1.000 52.770  ? 1425 ILE AAA N    1 
ATOM   2704 C CA   . ILE A 1 164 ? -30.025 -9.197  8.243  1.000 45.150  ? 1425 ILE AAA CA   1 
ATOM   2705 C C    . ILE A 1 164 ? -29.488 -10.594 7.911  1.000 46.530  ? 1425 ILE AAA C    1 
ATOM   2706 O O    . ILE A 1 164 ? -28.423 -10.953 8.405  1.000 58.350  ? 1425 ILE AAA O    1 
ATOM   2707 C CB   . ILE A 1 164 ? -31.178 -9.222  9.272  1.000 48.470  ? 1425 ILE AAA CB   1 
ATOM   2708 C CG1  . ILE A 1 164 ? -31.436 -7.824  9.835  1.000 43.290  ? 1425 ILE AAA CG1  1 
ATOM   2709 C CG2  . ILE A 1 164 ? -30.972 -10.233 10.390 1.000 48.240  ? 1425 ILE AAA CG2  1 
ATOM   2710 C CD1  . ILE A 1 164 ? -32.801 -7.678  10.420 1.000 44.770  ? 1425 ILE AAA CD1  1 
ATOM   2711 H H    . ILE A 1 164 ? -31.425 -8.152  6.945  1.000 52.770  ? 1425 ILE AAA H    1 
ATOM   2712 H HA   . ILE A 1 164 ? -29.296 -8.678  8.626  1.000 45.150  ? 1425 ILE AAA HA   1 
ATOM   2713 H HB   . ILE A 1 164 ? -31.997 -9.501  8.792  1.000 48.470  ? 1425 ILE AAA HB   1 
ATOM   2714 H HG12 . ILE A 1 164 ? -30.765 -7.634  10.525 1.000 43.290  ? 1425 ILE AAA HG12 1 
ATOM   2715 H HG13 . ILE A 1 164 ? -31.320 -7.168  9.114  1.000 43.290  ? 1425 ILE AAA HG13 1 
ATOM   2716 H HG21 . ILE A 1 164 ? -30.903 -11.128 10.014 1.000 48.240  ? 1425 ILE AAA HG21 1 
ATOM   2717 H HG22 . ILE A 1 164 ? -31.728 -10.204 11.001 1.000 48.240  ? 1425 ILE AAA HG22 1 
ATOM   2718 H HG23 . ILE A 1 164 ? -30.155 -10.023 10.875 1.000 48.240  ? 1425 ILE AAA HG23 1 
ATOM   2719 H HD11 . ILE A 1 164 ? -33.470 -7.849  9.734  1.000 44.770  ? 1425 ILE AAA HD11 1 
ATOM   2720 H HD12 . ILE A 1 164 ? -32.914 -6.774  10.763 1.000 44.770  ? 1425 ILE AAA HD12 1 
ATOM   2721 H HD13 . ILE A 1 164 ? -32.914 -8.315  11.147 1.000 44.770  ? 1425 ILE AAA HD13 1 
ATOM   2722 N N    . ARG A 1 165 ? -30.194 -11.362 7.092  1.000 52.650  ? 1426 ARG AAA N    1 
ATOM   2723 C CA   . ARG A 1 165 ? -29.783 -12.728 6.648  1.000 52.420  ? 1426 ARG AAA CA   1 
ATOM   2724 C C    . ARG A 1 165 ? -28.543 -12.613 5.750  1.000 55.480  ? 1426 ARG AAA C    1 
ATOM   2725 O O    . ARG A 1 165 ? -27.607 -13.406 5.932  1.000 54.180  ? 1426 ARG AAA O    1 
ATOM   2726 C CB   . ARG A 1 165 ? -30.964 -13.413 5.940  1.000 53.840  ? 1426 ARG AAA CB   1 
ATOM   2727 C CG   . ARG A 1 165 ? -32.135 -13.734 6.864  1.000 56.230  ? 1426 ARG AAA CG   1 
ATOM   2728 C CD   . ARG A 1 165 ? -31.753 -14.727 7.946  1.000 59.470  ? 1426 ARG AAA CD   1 
ATOM   2729 N NE   . ARG A 1 165 ? -32.849 -15.054 8.856  1.000 64.880  ? 1426 ARG AAA NE   1 
ATOM   2730 C CZ   . ARG A 1 165 ? -32.824 -14.961 10.191 1.000 62.810  ? 1426 ARG AAA CZ   1 
ATOM   2731 N NH1  . ARG A 1 165 ? -31.753 -14.543 10.847 1.000 61.380  ? 1426 ARG AAA NH1  1 
ATOM   2732 N NH2  . ARG A 1 165 ? -33.893 -15.302 10.879 1.000 59.070  ? 1426 ARG AAA NH2  1 
ATOM   2733 H H    . ARG A 1 165 ? -31.066 -10.977 6.758  1.000 52.650  ? 1426 ARG AAA H    1 
ATOM   2734 H HA   . ARG A 1 165 ? -29.551 -13.259 7.445  1.000 52.420  ? 1426 ARG AAA HA   1 
ATOM   2735 H HB2  . ARG A 1 165 ? -31.279 -12.827 5.220  1.000 53.840  ? 1426 ARG AAA HB2  1 
ATOM   2736 H HB3  . ARG A 1 165 ? -30.643 -14.245 5.533  1.000 53.840  ? 1426 ARG AAA HB3  1 
ATOM   2737 H HG2  . ARG A 1 165 ? -32.451 -12.906 7.285  1.000 56.230  ? 1426 ARG AAA HG2  1 
ATOM   2738 H HG3  . ARG A 1 165 ? -32.873 -14.104 6.334  1.000 56.230  ? 1426 ARG AAA HG3  1 
ATOM   2739 H HD2  . ARG A 1 165 ? -31.439 -15.556 7.526  1.000 59.470  ? 1426 ARG AAA HD2  1 
ATOM   2740 H HD3  . ARG A 1 165 ? -31.010 -14.361 8.472  1.000 59.470  ? 1426 ARG AAA HD3  1 
ATOM   2741 H HE   . ARG A 1 165 ? -33.597 -15.338 8.509  1.000 64.880  ? 1426 ARG AAA HE   1 
ATOM   2742 H HH11 . ARG A 1 165 ? -31.029 -14.316 10.403 1.000 61.380  ? 1426 ARG AAA HH11 1 
ATOM   2743 H HH12 . ARG A 1 165 ? -31.769 -14.493 11.724 1.000 61.380  ? 1426 ARG AAA HH12 1 
ATOM   2744 H HH21 . ARG A 1 165 ? -34.613 -15.587 10.458 1.000 59.070  ? 1426 ARG AAA HH21 1 
ATOM   2745 H HH22 . ARG A 1 165 ? -33.886 -15.244 11.758 1.000 59.070  ? 1426 ARG AAA HH22 1 
ATOM   2746 N N    . LEU A 1 166 ? -28.546 -11.646 4.826  1.000 52.990  ? 1427 LEU AAA N    1 
ATOM   2747 C CA   . LEU A 1 166 ? -27.389 -11.291 3.953  1.000 53.560  ? 1427 LEU AAA CA   1 
ATOM   2748 C C    . LEU A 1 166 ? -26.129 -11.034 4.785  1.000 58.440  ? 1427 LEU AAA C    1 
ATOM   2749 O O    . LEU A 1 166 ? -25.074 -11.604 4.424  1.000 69.690  ? 1427 LEU AAA O    1 
ATOM   2750 C CB   . LEU A 1 166 ? -27.730 -10.056 3.113  1.000 56.310  ? 1427 LEU AAA CB   1 
ATOM   2751 C CG   . LEU A 1 166 ? -27.413 -10.205 1.634  1.000 59.180  ? 1427 LEU AAA CG   1 
ATOM   2752 C CD1  . LEU A 1 166 ? -28.438 -11.109 0.970  1.000 70.210  ? 1427 LEU AAA CD1  1 
ATOM   2753 C CD2  . LEU A 1 166 ? -27.362 -8.852  0.964  1.000 58.880  ? 1427 LEU AAA CD2  1 
ATOM   2754 H H    . LEU A 1 166 ? -29.410 -11.131 4.732  1.000 52.990  ? 1427 LEU AAA H    1 
ATOM   2755 H HA   . LEU A 1 166 ? -27.206 -12.050 3.352  1.000 53.560  ? 1427 LEU AAA HA   1 
ATOM   2756 H HB2  . LEU A 1 166 ? -28.683 -9.865  3.220  1.000 56.310  ? 1427 LEU AAA HB2  1 
ATOM   2757 H HB3  . LEU A 1 166 ? -27.235 -9.293  3.473  1.000 56.310  ? 1427 LEU AAA HB3  1 
ATOM   2758 H HG   . LEU A 1 166 ? -26.521 -10.624 1.552  1.000 59.180  ? 1427 LEU AAA HG   1 
ATOM   2759 H HD11 . LEU A 1 166 ? -28.419 -11.986 1.391  1.000 70.210  ? 1427 LEU AAA HD11 1 
ATOM   2760 H HD12 . LEU A 1 166 ? -28.228 -11.198 0.024  1.000 70.210  ? 1427 LEU AAA HD12 1 
ATOM   2761 H HD13 . LEU A 1 166 ? -29.325 -10.722 1.069  1.000 70.210  ? 1427 LEU AAA HD13 1 
ATOM   2762 H HD21 . LEU A 1 166 ? -28.223 -8.410  1.060  1.000 58.880  ? 1427 LEU AAA HD21 1 
ATOM   2763 H HD22 . LEU A 1 166 ? -27.158 -8.965  0.019  1.000 58.880  ? 1427 LEU AAA HD22 1 
ATOM   2764 H HD23 . LEU A 1 166 ? -26.671 -8.309  1.382  1.000 58.880  ? 1427 LEU AAA HD23 1 
ATOM   2765 N N    . ILE A 1 167 ? -26.231 -10.198 5.829  1.000 56.610  ? 1428 ILE AAA N    1 
ATOM   2766 C CA   . ILE A 1 167 ? -25.101 -9.835  6.734  1.000 47.510  ? 1428 ILE AAA CA   1 
ATOM   2767 C C    . ILE A 1 167 ? -24.591 -11.108 7.386  1.000 50.490  ? 1428 ILE AAA C    1 
ATOM   2768 O O    . ILE A 1 167 ? -23.374 -11.262 7.455  1.000 61.170  ? 1428 ILE AAA O    1 
ATOM   2769 C CB   . ILE A 1 167 ? -25.498 -8.789  7.791  1.000 44.680  ? 1428 ILE AAA CB   1 
ATOM   2770 C CG1  . ILE A 1 167 ? -25.702 -7.404  7.172  1.000 42.960  ? 1428 ILE AAA CG1  1 
ATOM   2771 C CG2  . ILE A 1 167 ? -24.489 -8.756  8.939  1.000 42.810  ? 1428 ILE AAA CG2  1 
ATOM   2772 C CD1  . ILE A 1 167 ? -26.371 -6.425  8.096  1.000 44.240  ? 1428 ILE AAA CD1  1 
ATOM   2773 H H    . ILE A 1 167 ? -27.143 -9.798  5.996  1.000 56.610  ? 1428 ILE AAA H    1 
ATOM   2774 H HA   . ILE A 1 167 ? -24.387 -9.450  6.195  1.000 47.510  ? 1428 ILE AAA HA   1 
ATOM   2775 H HB   . ILE A 1 167 ? -26.369 -9.066  8.169  1.000 44.680  ? 1428 ILE AAA HB   1 
ATOM   2776 H HG12 . ILE A 1 167 ? -24.828 -7.046  6.908  1.000 42.960  ? 1428 ILE AAA HG12 1 
ATOM   2777 H HG13 . ILE A 1 167 ? -26.246 -7.499  6.361  1.000 42.960  ? 1428 ILE AAA HG13 1 
ATOM   2778 H HG21 . ILE A 1 167 ? -24.453 -9.628  9.368  1.000 42.810  ? 1428 ILE AAA HG21 1 
ATOM   2779 H HG22 . ILE A 1 167 ? -24.761 -8.091  9.595  1.000 42.810  ? 1428 ILE AAA HG22 1 
ATOM   2780 H HG23 . ILE A 1 167 ? -23.608 -8.529  8.594  1.000 42.810  ? 1428 ILE AAA HG23 1 
ATOM   2781 H HD11 . ILE A 1 167 ? -27.248 -6.762  8.348  1.000 44.240  ? 1428 ILE AAA HD11 1 
ATOM   2782 H HD12 . ILE A 1 167 ? -26.471 -5.568  7.646  1.000 44.240  ? 1428 ILE AAA HD12 1 
ATOM   2783 H HD13 . ILE A 1 167 ? -25.828 -6.308  8.895  1.000 44.240  ? 1428 ILE AAA HD13 1 
ATOM   2784 N N    . GLU A 1 168 ? -25.492 -11.971 7.846  1.000 54.510  ? 1429 GLU AAA N    1 
ATOM   2785 C CA   . GLU A 1 168 ? -25.116 -13.245 8.507  1.000 60.240  ? 1429 GLU AAA CA   1 
ATOM   2786 C C    . GLU A 1 168 ? -24.356 -14.128 7.511  1.000 63.850  ? 1429 GLU AAA C    1 
ATOM   2787 O O    . GLU A 1 168 ? -23.414 -14.805 7.948  1.000 66.400  ? 1429 GLU AAA O    1 
ATOM   2788 C CB   . GLU A 1 168 ? -26.355 -13.989 9.000  1.000 57.130  ? 1429 GLU AAA CB   1 
ATOM   2789 C CG   . GLU A 1 168 ? -26.970 -13.390 10.237 1.000 53.700  ? 1429 GLU AAA CG   1 
ATOM   2790 C CD   . GLU A 1 168 ? -28.062 -14.283 10.791 1.000 55.070  ? 1429 GLU AAA CD   1 
ATOM   2791 O OE1  . GLU A 1 168 ? -29.030 -14.581 10.060 1.000 63.520  ? 1429 GLU AAA OE1  1 
ATOM   2792 O OE2  . GLU A 1 168 ? -27.924 -14.721 11.921 1.000 57.610  ? 1429 GLU AAA OE2  1 
ATOM   2793 H H    . GLU A 1 168 ? -26.470 -11.743 7.737  1.000 54.510  ? 1429 GLU AAA H    1 
ATOM   2794 H HA   . GLU A 1 168 ? -24.523 -13.040 9.266  1.000 60.240  ? 1429 GLU AAA HA   1 
ATOM   2795 H HB2  . GLU A 1 168 ? -27.024 -13.989 8.284  1.000 57.130  ? 1429 GLU AAA HB2  1 
ATOM   2796 H HB3  . GLU A 1 168 ? -26.106 -14.917 9.190  1.000 57.130  ? 1429 GLU AAA HB3  1 
ATOM   2797 H HG2  . GLU A 1 168 ? -26.267 -13.257 10.909 1.000 53.700  ? 1429 GLU AAA HG2  1 
ATOM   2798 H HG3  . GLU A 1 168 ? -27.334 -12.507 10.015 1.000 53.700  ? 1429 GLU AAA HG3  1 
ATOM   2799 N N    . LYS A 1 169 ? -24.777 -14.133 6.238  1.000 67.210  ? 1430 LYS AAA N    1 
ATOM   2800 C CA   . LYS A 1 169 ? -24.182 -14.975 5.163  1.000 76.750  ? 1430 LYS AAA CA   1 
ATOM   2801 C C    . LYS A 1 169 ? -22.696 -14.603 5.014  1.000 77.800  ? 1430 LYS AAA C    1 
ATOM   2802 O O    . LYS A 1 169 ? -21.857 -15.521 5.145  1.000 75.360  ? 1430 LYS AAA O    1 
ATOM   2803 C CB   . LYS A 1 169 ? -24.963 -14.835 3.847  1.000 71.290  ? 1430 LYS AAA CB   1 
ATOM   2804 C CG   . LYS A 1 169 ? -24.369 -15.608 2.674  1.000 77.800  ? 1430 LYS AAA CG   1 
ATOM   2805 C CD   . LYS A 1 169 ? -25.363 -15.991 1.614  1.000 81.040  ? 1430 LYS AAA CD   1 
ATOM   2806 C CE   . LYS A 1 169 ? -26.462 -16.868 2.179  1.000 100.300 ? 1430 LYS AAA CE   1 
ATOM   2807 N NZ   . LYS A 1 169 ? -27.129 -17.676 1.130  1.000 106.380 ? 1430 LYS AAA NZ   1 
ATOM   2808 H H    . LYS A 1 169 ? -25.548 -13.520 6.014  1.000 67.210  ? 1430 LYS AAA H    1 
ATOM   2809 H HA   . LYS A 1 169 ? -24.253 -15.920 5.431  1.000 76.750  ? 1430 LYS AAA HA   1 
ATOM   2810 H HB2  . LYS A 1 169 ? -25.883 -15.137 3.997  1.000 71.290  ? 1430 LYS AAA HB2  1 
ATOM   2811 H HB3  . LYS A 1 169 ? -25.011 -13.885 3.613  1.000 71.290  ? 1430 LYS AAA HB3  1 
ATOM   2812 H HG2  . LYS A 1 169 ? -23.673 -15.057 2.257  1.000 77.800  ? 1430 LYS AAA HG2  1 
ATOM   2813 H HG3  . LYS A 1 169 ? -23.955 -16.429 3.017  1.000 77.800  ? 1430 LYS AAA HG3  1 
ATOM   2814 H HD2  . LYS A 1 169 ? -25.753 -15.176 1.231  1.000 81.040  ? 1430 LYS AAA HD2  1 
ATOM   2815 H HD3  . LYS A 1 169 ? -24.896 -16.467 0.894  1.000 81.040  ? 1430 LYS AAA HD3  1 
ATOM   2816 H HE2  . LYS A 1 169 ? -26.087 -17.471 2.849  1.000 100.300 ? 1430 LYS AAA HE2  1 
ATOM   2817 H HE3  . LYS A 1 169 ? -27.132 -16.311 2.619  1.000 100.300 ? 1430 LYS AAA HE3  1 
ATOM   2818 H HZ1  . LYS A 1 169 ? -27.498 -17.128 0.509  1.000 106.380 ? 1430 LYS AAA HZ1  1 
ATOM   2819 H HZ2  . LYS A 1 169 ? -27.777 -18.189 1.503  1.000 106.380 ? 1430 LYS AAA HZ2  1 
ATOM   2820 H HZ3  . LYS A 1 169 ? -26.522 -18.215 0.725  1.000 106.380 ? 1430 LYS AAA HZ3  1 
ATOM   2821 N N    . GLN A 1 170 ? -22.394 -13.303 4.855  1.000 74.070  ? 1431 GLN AAA N    1 
ATOM   2822 C CA   . GLN A 1 170 ? -21.051 -12.743 4.516  1.000 65.110  ? 1431 GLN AAA CA   1 
ATOM   2823 C C    . GLN A 1 170 ? -19.959 -13.169 5.502  1.000 64.210  ? 1431 GLN AAA C    1 
ATOM   2824 O O    . GLN A 1 170 ? -18.803 -12.929 5.139  1.000 66.840  ? 1431 GLN AAA O    1 
ATOM   2825 C CB   . GLN A 1 170 ? -21.001 -11.213 4.555  1.000 64.990  ? 1431 GLN AAA CB   1 
ATOM   2826 C CG   . GLN A 1 170 ? -22.073 -10.512 3.734  1.000 71.930  ? 1431 GLN AAA CG   1 
ATOM   2827 C CD   . GLN A 1 170 ? -22.284 -11.130 2.376  1.000 71.320  ? 1431 GLN AAA CD   1 
ATOM   2828 O OE1  . GLN A 1 170 ? -21.446 -11.009 1.489  1.000 70.480  ? 1431 GLN AAA OE1  1 
ATOM   2829 N NE2  . GLN A 1 170 ? -23.425 -11.773 2.203  1.000 66.160  ? 1431 GLN AAA NE2  1 
ATOM   2830 H H    . GLN A 1 170 ? -23.172 -12.672 4.984  1.000 74.070  ? 1431 GLN AAA H    1 
ATOM   2831 H HA   . GLN A 1 170 ? -20.787 -13.081 3.629  1.000 65.110  ? 1431 GLN AAA HA   1 
ATOM   2832 H HB2  . GLN A 1 170 ? -21.087 -10.922 5.487  1.000 64.990  ? 1431 GLN AAA HB2  1 
ATOM   2833 H HB3  . GLN A 1 170 ? -20.124 -10.921 4.230  1.000 64.990  ? 1431 GLN AAA HB3  1 
ATOM   2834 H HG2  . GLN A 1 170 ? -22.923 -10.538 4.223  1.000 71.930  ? 1431 GLN AAA HG2  1 
ATOM   2835 H HG3  . GLN A 1 170 ? -21.823 -9.571  3.613  1.000 71.930  ? 1431 GLN AAA HG3  1 
ATOM   2836 H HE21 . GLN A 1 170 ? -23.604 -12.156 1.426  0.000 66.160  ? 1431 GLN AAA HE21 1 
ATOM   2837 H HE22 . GLN A 1 170 ? -24.010 -11.821 2.864  0.000 66.160  ? 1431 GLN AAA HE22 1 
ATOM   2838 N N    . ALA A 1 171 ? -20.267 -13.702 6.697  1.000 60.670  ? 1432 ALA AAA N    1 
ATOM   2839 C CA   . ALA A 1 171 ? -19.237 -14.098 7.691  1.000 60.000  ? 1432 ALA AAA CA   1 
ATOM   2840 C C    . ALA A 1 171 ? -19.840 -14.806 8.899  1.000 59.300  ? 1432 ALA AAA C    1 
ATOM   2841 O O    . ALA A 1 171 ? -20.907 -14.454 9.369  1.000 65.480  ? 1432 ALA AAA O    1 
ATOM   2842 C CB   . ALA A 1 171 ? -18.455 -12.886 8.135  1.000 64.250  ? 1432 ALA AAA CB   1 
ATOM   2843 H H    . ALA A 1 171 ? -21.243 -13.835 6.920  1.000 60.670  ? 1432 ALA AAA H    1 
ATOM   2844 H HA   . ALA A 1 171 ? -18.614 -14.731 7.262  1.000 60.000  ? 1432 ALA AAA HA   1 
ATOM   2845 H HB1  . ALA A 1 171 ? -17.785 -13.152 8.784  1.000 64.250  ? 1432 ALA AAA HB1  1 
ATOM   2846 H HB2  . ALA A 1 171 ? -18.019 -12.483 7.368  1.000 64.250  ? 1432 ALA AAA HB2  1 
ATOM   2847 H HB3  . ALA A 1 171 ? -19.058 -12.240 8.540  1.000 64.250  ? 1432 ALA AAA HB3  1 
ATOM   2848 N N    . PRO A 1 172 ? -19.141 -15.802 9.471  1.000 68.090  ? 1433 PRO AAA N    1 
ATOM   2849 C CA   . PRO A 1 172 ? -19.721 -16.643 10.516 1.000 66.370  ? 1433 PRO AAA CA   1 
ATOM   2850 C C    . PRO A 1 172 ? -19.908 -16.052 11.920 1.000 64.260  ? 1433 PRO AAA C    1 
ATOM   2851 O O    . PRO A 1 172 ? -20.754 -16.563 12.589 1.000 75.770  ? 1433 PRO AAA O    1 
ATOM   2852 C CB   . PRO A 1 172 ? -18.744 -17.826 10.574 1.000 73.220  ? 1433 PRO AAA CB   1 
ATOM   2853 C CG   . PRO A 1 172 ? -17.420 -17.246 10.122 1.000 77.560  ? 1433 PRO AAA CG   1 
ATOM   2854 C CD   . PRO A 1 172 ? -17.801 -16.247 9.053  1.000 75.710  ? 1433 PRO AAA CD   1 
ATOM   2855 H HA   . PRO A 1 172 ? -20.616 -16.953 10.227 1.000 66.370  ? 1433 PRO AAA HA   1 
ATOM   2856 H HB2  . PRO A 1 172 ? -18.682 -18.186 11.483 1.000 73.220  ? 1433 PRO AAA HB2  1 
ATOM   2857 H HB3  . PRO A 1 172 ? -19.034 -18.551 9.982  1.000 73.220  ? 1433 PRO AAA HB3  1 
ATOM   2858 H HG2  . PRO A 1 172 ? -16.956 -16.813 10.869 1.000 77.560  ? 1433 PRO AAA HG2  1 
ATOM   2859 H HG3  . PRO A 1 172 ? -16.835 -17.947 9.766  1.000 77.560  ? 1433 PRO AAA HG3  1 
ATOM   2860 H HD2  . PRO A 1 172 ? -17.161 -15.505 9.024  1.000 75.710  ? 1433 PRO AAA HD2  1 
ATOM   2861 H HD3  . PRO A 1 172 ? -17.815 -16.670 8.169  1.000 75.710  ? 1433 PRO AAA HD3  1 
ATOM   2862 N N    . GLU A 1 173 ? -19.152 -15.038 12.352 1.000 73.670  ? 1434 GLU AAA N    1 
ATOM   2863 C CA   . GLU A 1 173 ? -19.341 -14.388 13.692 1.000 71.500  ? 1434 GLU AAA CA   1 
ATOM   2864 C C    . GLU A 1 173 ? -20.466 -13.350 13.605 1.000 66.100  ? 1434 GLU AAA C    1 
ATOM   2865 O O    . GLU A 1 173 ? -20.984 -12.935 14.688 1.000 64.060  ? 1434 GLU AAA O    1 
ATOM   2866 C CB   . GLU A 1 173 ? -18.114 -13.621 14.207 1.000 87.590  ? 1434 GLU AAA CB   1 
ATOM   2867 C CG   . GLU A 1 173 ? -16.773 -14.313 14.025 1.000 87.480  ? 1434 GLU AAA CG   1 
ATOM   2868 C CD   . GLU A 1 173 ? -16.144 -14.174 12.645 1.000 89.390  ? 1434 GLU AAA CD   1 
ATOM   2869 O OE1  . GLU A 1 173 ? -16.848 -13.769 11.681 1.000 88.830  ? 1434 GLU AAA OE1  1 
ATOM   2870 O OE2  . GLU A 1 173 ? -14.953 -14.500 12.529 1.000 105.250 ? 1434 GLU AAA OE2  1 
ATOM   2871 H H    . GLU A 1 173 ? -18.422 -14.701 11.740 1.000 73.670  ? 1434 GLU AAA H    1 
ATOM   2872 H HA   . GLU A 1 173 ? -19.601 -15.081 14.342 1.000 71.500  ? 1434 GLU AAA HA   1 
ATOM   2873 H HB2  . GLU A 1 173 ? -18.068 -12.759 13.743 1.000 87.590  ? 1434 GLU AAA HB2  1 
ATOM   2874 H HB3  . GLU A 1 173 ? -18.232 -13.451 15.165 1.000 87.590  ? 1434 GLU AAA HB3  1 
ATOM   2875 H HG2  . GLU A 1 173 ? -16.139 -13.956 14.683 1.000 87.480  ? 1434 GLU AAA HG2  1 
ATOM   2876 H HG3  . GLU A 1 173 ? -16.881 -15.270 14.212 1.000 87.480  ? 1434 GLU AAA HG3  1 
ATOM   2877 N N    . ASN A 1 174 ? -20.759 -12.899 12.374 1.000 56.910  ? 1435 ASN AAA N    1 
ATOM   2878 C CA   . ASN A 1 174 ? -21.920 -12.047 12.022 1.000 52.900  ? 1435 ASN AAA CA   1 
ATOM   2879 C C    . ASN A 1 174 ? -23.179 -12.827 12.371 1.000 54.180  ? 1435 ASN AAA C    1 
ATOM   2880 O O    . ASN A 1 174 ? -23.500 -13.751 11.621 1.000 65.700  ? 1435 ASN AAA O    1 
ATOM   2881 C CB   . ASN A 1 174 ? -21.948 -11.669 10.542 1.000 56.660  ? 1435 ASN AAA CB   1 
ATOM   2882 C CG   . ASN A 1 174 ? -20.885 -10.669 10.138 1.000 54.990  ? 1435 ASN AAA CG   1 
ATOM   2883 O OD1  . ASN A 1 174 ? -19.957 -10.409 10.894 1.000 59.250  ? 1435 ASN AAA OD1  1 
ATOM   2884 N ND2  . ASN A 1 174 ? -21.024 -10.091 8.956  1.000 50.380  ? 1435 ASN AAA ND2  1 
ATOM   2885 H H    . ASN A 1 174 ? -20.116 -13.180 11.647 1.000 56.910  ? 1435 ASN AAA H    1 
ATOM   2886 H HA   . ASN A 1 174 ? -21.879 -11.223 12.563 1.000 52.900  ? 1435 ASN AAA HA   1 
ATOM   2887 H HB2  . ASN A 1 174 ? -21.831 -12.479 10.005 1.000 56.660  ? 1435 ASN AAA HB2  1 
ATOM   2888 H HB3  . ASN A 1 174 ? -22.826 -11.292 10.327 1.000 56.660  ? 1435 ASN AAA HB3  1 
ATOM   2889 H HD21 . ASN A 1 174 ? -20.427 -9.501  8.679  0.000 50.380  ? 1435 ASN AAA HD21 1 
ATOM   2890 H HD22 . ASN A 1 174 ? -21.714 -10.295 8.442  0.000 50.380  ? 1435 ASN AAA HD22 1 
ATOM   2891 N N    . LYS A 1 175 ? -23.823 -12.465 13.476 1.000 57.780  ? 1436 LYS AAA N    1 
ATOM   2892 C CA   . LYS A 1 175 ? -24.897 -13.239 14.145 1.000 62.370  ? 1436 LYS AAA CA   1 
ATOM   2893 C C    . LYS A 1 175 ? -26.025 -12.257 14.481 1.000 58.260  ? 1436 LYS AAA C    1 
ATOM   2894 O O    . LYS A 1 175 ? -25.709 -11.170 14.975 1.000 59.190  ? 1436 LYS AAA O    1 
ATOM   2895 C CB   . LYS A 1 175 ? -24.290 -13.910 15.385 1.000 66.890  ? 1436 LYS AAA CB   1 
ATOM   2896 C CG   . LYS A 1 175 ? -25.218 -14.822 16.172 1.000 68.260  ? 1436 LYS AAA CG   1 
ATOM   2897 C CD   . LYS A 1 175 ? -26.052 -14.072 17.188 1.000 73.320  ? 1436 LYS AAA CD   1 
ATOM   2898 C CE   . LYS A 1 175 ? -27.366 -14.746 17.517 1.000 77.480  ? 1436 LYS AAA CE   1 
ATOM   2899 N NZ   . LYS A 1 175 ? -27.172 -15.806 18.528 1.000 86.320  ? 1436 LYS AAA NZ   1 
ATOM   2900 H H    . LYS A 1 175 ? -23.534 -11.582 13.871 1.000 57.780  ? 1436 LYS AAA H    1 
ATOM   2901 H HA   . LYS A 1 175 ? -25.227 -13.922 13.517 1.000 62.370  ? 1436 LYS AAA HA   1 
ATOM   2902 H HB2  . LYS A 1 175 ? -23.510 -14.433 15.106 1.000 66.890  ? 1436 LYS AAA HB2  1 
ATOM   2903 H HB3  . LYS A 1 175 ? -23.962 -13.211 15.988 1.000 66.890  ? 1436 LYS AAA HB3  1 
ATOM   2904 H HG2  . LYS A 1 175 ? -25.815 -15.280 15.542 1.000 68.260  ? 1436 LYS AAA HG2  1 
ATOM   2905 H HG3  . LYS A 1 175 ? -24.676 -15.495 16.636 1.000 68.260  ? 1436 LYS AAA HG3  1 
ATOM   2906 H HD2  . LYS A 1 175 ? -25.536 -13.975 18.017 1.000 73.320  ? 1436 LYS AAA HD2  1 
ATOM   2907 H HD3  . LYS A 1 175 ? -26.241 -13.172 16.846 1.000 73.320  ? 1436 LYS AAA HD3  1 
ATOM   2908 H HE2  . LYS A 1 175 ? -27.997 -14.084 17.857 1.000 77.480  ? 1436 LYS AAA HE2  1 
ATOM   2909 H HE3  . LYS A 1 175 ? -27.746 -15.135 16.706 1.000 77.480  ? 1436 LYS AAA HE3  1 
ATOM   2910 H HZ1  . LYS A 1 175 ? -26.594 -16.430 18.212 1.000 86.320  ? 1436 LYS AAA HZ1  1 
ATOM   2911 H HZ2  . LYS A 1 175 ? -27.967 -16.199 18.717 1.000 86.320  ? 1436 LYS AAA HZ2  1 
ATOM   2912 H HZ3  . LYS A 1 175 ? -26.832 -15.447 19.288 1.000 86.320  ? 1436 LYS AAA HZ3  1 
ATOM   2913 N N    . ALA A 1 176 ? -27.285 -12.618 14.251 1.000 51.350  ? 1437 ALA AAA N    1 
ATOM   2914 C CA   . ALA A 1 176 ? -28.429 -11.673 14.260 1.000 47.430  ? 1437 ALA AAA CA   1 
ATOM   2915 C C    . ALA A 1 176 ? -29.364 -11.979 15.432 1.000 43.790  ? 1437 ALA AAA C    1 
ATOM   2916 O O    . ALA A 1 176 ? -29.406 -13.148 15.888 1.000 41.470  ? 1437 ALA AAA O    1 
ATOM   2917 C CB   . ALA A 1 176 ? -29.165 -11.758 12.944 1.000 52.830  ? 1437 ALA AAA CB   1 
ATOM   2918 H H    . ALA A 1 176 ? -27.455 -13.595 14.061 1.000 51.350  ? 1437 ALA AAA H    1 
ATOM   2919 H HA   . ALA A 1 176 ? -28.079 -10.759 14.376 1.000 47.430  ? 1437 ALA AAA HA   1 
ATOM   2920 H HB1  . ALA A 1 176 ? -29.913 -11.140 12.950 1.000 52.830  ? 1437 ALA AAA HB1  1 
ATOM   2921 H HB2  . ALA A 1 176 ? -28.562 -11.528 12.220 1.000 52.830  ? 1437 ALA AAA HB2  1 
ATOM   2922 H HB3  . ALA A 1 176 ? -29.495 -12.663 12.814 1.000 52.830  ? 1437 ALA AAA HB3  1 
ATOM   2923 N N    . PHE A 1 177 ? -30.038 -10.939 15.912 1.000 42.330  ? 1438 PHE AAA N    1 
ATOM   2924 C CA   . PHE A 1 177 ? -31.122 -10.934 16.922 1.000 41.280  ? 1438 PHE AAA CA   1 
ATOM   2925 C C    . PHE A 1 177 ? -32.347 -10.340 16.245 1.000 43.200  ? 1438 PHE AAA C    1 
ATOM   2926 O O    . PHE A 1 177 ? -32.257 -9.210  15.770 1.000 55.760  ? 1438 PHE AAA O    1 
ATOM   2927 C CB   . PHE A 1 177 ? -30.709 -10.069 18.122 1.000 43.930  ? 1438 PHE AAA CB   1 
ATOM   2928 C CG   . PHE A 1 177 ? -29.557 -10.668 18.874 1.000 44.930  ? 1438 PHE AAA CG   1 
ATOM   2929 C CD1  . PHE A 1 177 ? -29.778 -11.594 19.878 1.000 46.290  ? 1438 PHE AAA CD1  1 
ATOM   2930 C CD2  . PHE A 1 177 ? -28.252 -10.364 18.532 1.000 46.720  ? 1438 PHE AAA CD2  1 
ATOM   2931 C CE1  . PHE A 1 177 ? -28.714 -12.176 20.553 1.000 48.360  ? 1438 PHE AAA CE1  1 
ATOM   2932 C CE2  . PHE A 1 177 ? -27.190 -10.968 19.190 1.000 47.000  ? 1438 PHE AAA CE2  1 
ATOM   2933 C CZ   . PHE A 1 177 ? -27.421 -11.884 20.186 1.000 46.680  ? 1438 PHE AAA CZ   1 
ATOM   2934 H H    . PHE A 1 177 ? -29.738 -10.064 15.507 1.000 42.330  ? 1438 PHE AAA H    1 
ATOM   2935 H HA   . PHE A 1 177 ? -31.308 -11.870 17.190 1.000 41.280  ? 1438 PHE AAA HA   1 
ATOM   2936 H HB2  . PHE A 1 177 ? -30.474 -9.176  17.794 1.000 43.930  ? 1438 PHE AAA HB2  1 
ATOM   2937 H HB3  . PHE A 1 177 ? -31.485 -9.967  18.712 1.000 43.930  ? 1438 PHE AAA HB3  1 
ATOM   2938 H HD1  . PHE A 1 177 ? -30.662 -11.850 20.090 1.000 46.290  ? 1438 PHE AAA HD1  1 
ATOM   2939 H HD2  . PHE A 1 177 ? -28.084 -9.740  17.844 1.000 46.720  ? 1438 PHE AAA HD2  1 
ATOM   2940 H HE1  . PHE A 1 177 ? -28.880 -12.806 21.236 1.000 48.360  ? 1438 PHE AAA HE1  1 
ATOM   2941 H HE2  . PHE A 1 177 ? -26.304 -10.764 18.935 1.000 47.000  ? 1438 PHE AAA HE2  1 
ATOM   2942 H HZ   . PHE A 1 177 ? -26.699 -12.281 20.646 1.000 46.680  ? 1438 PHE AAA HZ   1 
ATOM   2943 N N    . VAL A 1 178 ? -33.435 -11.085 16.121 1.000 52.350  ? 1439 VAL AAA N    1 
ATOM   2944 C CA   . VAL A 1 178 ? -34.674 -10.576 15.455 1.000 49.740  ? 1439 VAL AAA CA   1 
ATOM   2945 C C    . VAL A 1 178 ? -35.743 -10.362 16.533 1.000 50.820  ? 1439 VAL AAA C    1 
ATOM   2946 O O    . VAL A 1 178 ? -36.207 -11.362 17.092 1.000 51.380  ? 1439 VAL AAA O    1 
ATOM   2947 C CB   . VAL A 1 178 ? -35.146 -11.522 14.338 1.000 48.610  ? 1439 VAL AAA CB   1 
ATOM   2948 C CG1  . VAL A 1 178 ? -36.241 -10.888 13.487 1.000 53.420  ? 1439 VAL AAA CG1  1 
ATOM   2949 C CG2  . VAL A 1 178 ? -34.001 -11.961 13.441 1.000 48.650  ? 1439 VAL AAA CG2  1 
ATOM   2950 H H    . VAL A 1 178 ? -33.425 -12.026 16.489 1.000 52.350  ? 1439 VAL AAA H    1 
ATOM   2951 H HA   . VAL A 1 178 ? -34.470 -9.719  15.040 1.000 49.740  ? 1439 VAL AAA HA   1 
ATOM   2952 H HB   . VAL A 1 178 ? -35.509 -12.332 14.774 1.000 48.610  ? 1439 VAL AAA HB   1 
ATOM   2953 H HG11 . VAL A 1 178 ? -37.005 -10.672 14.049 1.000 53.420  ? 1439 VAL AAA HG11 1 
ATOM   2954 H HG12 . VAL A 1 178 ? -36.515 -11.512 12.792 1.000 53.420  ? 1439 VAL AAA HG12 1 
ATOM   2955 H HG13 . VAL A 1 178 ? -35.902 -10.074 13.076 1.000 53.420  ? 1439 VAL AAA HG13 1 
ATOM   2956 H HG21 . VAL A 1 178 ? -33.595 -11.180 13.026 1.000 48.650  ? 1439 VAL AAA HG21 1 
ATOM   2957 H HG22 . VAL A 1 178 ? -34.340 -12.557 12.750 1.000 48.650  ? 1439 VAL AAA HG22 1 
ATOM   2958 H HG23 . VAL A 1 178 ? -33.333 -12.428 13.972 1.000 48.650  ? 1439 VAL AAA HG23 1 
ATOM   2959 N N    . LEU A 1 179 ? -36.090 -9.101  16.806 1.000 49.940  ? 1440 LEU AAA N    1 
ATOM   2960 C CA   . LEU A 1 179 ? -36.994 -8.657  17.899 1.000 50.910  ? 1440 LEU AAA CA   1 
ATOM   2961 C C    . LEU A 1 179 ? -38.332 -8.199  17.296 1.000 51.800  ? 1440 LEU AAA C    1 
ATOM   2962 O O    . LEU A 1 179 ? -38.310 -7.533  16.247 1.000 54.650  ? 1440 LEU AAA O    1 
ATOM   2963 C CB   . LEU A 1 179 ? -36.323 -7.514  18.681 1.000 52.440  ? 1440 LEU AAA CB   1 
ATOM   2964 C CG   . LEU A 1 179 ? -35.307 -7.918  19.746 1.000 55.770  ? 1440 LEU AAA CG   1 
ATOM   2965 C CD1  . LEU A 1 179 ? -34.275 -8.863  19.186 1.000 54.760  ? 1440 LEU AAA CD1  1 
ATOM   2966 C CD2  . LEU A 1 179 ? -34.626 -6.704  20.351 1.000 61.260  ? 1440 LEU AAA CD2  1 
ATOM   2967 H H    . LEU A 1 179 ? -35.682 -8.410  16.193 1.000 49.940  ? 1440 LEU AAA H    1 
ATOM   2968 H HA   . LEU A 1 179 ? -37.160 -9.422  18.497 1.000 50.910  ? 1440 LEU AAA HA   1 
ATOM   2969 H HB2  . LEU A 1 179 ? -35.870 -6.928  18.042 1.000 52.440  ? 1440 LEU AAA HB2  1 
ATOM   2970 H HB3  . LEU A 1 179 ? -37.022 -6.988  19.118 1.000 52.440  ? 1440 LEU AAA HB3  1 
ATOM   2971 H HG   . LEU A 1 179 ? -35.792 -8.385  20.471 1.000 55.770  ? 1440 LEU AAA HG   1 
ATOM   2972 H HD11 . LEU A 1 179 ? -34.715 -9.666  18.856 1.000 54.760  ? 1440 LEU AAA HD11 1 
ATOM   2973 H HD12 . LEU A 1 179 ? -33.641 -9.103  19.884 1.000 54.760  ? 1440 LEU AAA HD12 1 
ATOM   2974 H HD13 . LEU A 1 179 ? -33.801 -8.430  18.455 1.000 54.760  ? 1440 LEU AAA HD13 1 
ATOM   2975 H HD21 . LEU A 1 179 ? -34.162 -6.210  19.653 1.000 61.260  ? 1440 LEU AAA HD21 1 
ATOM   2976 H HD22 . LEU A 1 179 ? -33.987 -6.993  21.025 1.000 61.260  ? 1440 LEU AAA HD22 1 
ATOM   2977 H HD23 . LEU A 1 179 ? -35.294 -6.129  20.764 1.000 61.260  ? 1440 LEU AAA HD23 1 
ATOM   2978 N N    . SER A 1 180 ? -39.451 -8.508  17.961 1.000 52.910  ? 1441 SER AAA N    1 
ATOM   2979 C CA   . SER A 1 180 ? -40.822 -8.106  17.547 1.000 52.700  ? 1441 SER AAA CA   1 
ATOM   2980 C C    . SER A 1 180 ? -41.059 -6.614  17.825 1.000 47.600  ? 1441 SER AAA C    1 
ATOM   2981 O O    . SER A 1 180 ? -41.943 -6.065  17.138 1.000 50.090  ? 1441 SER AAA O    1 
ATOM   2982 C CB   . SER A 1 180 ? -41.879 -8.962  18.206 1.000 55.730  ? 1441 SER AAA CB   1 
ATOM   2983 O OG   . SER A 1 180 ? -41.734 -8.950  19.628 1.000 60.390  ? 1441 SER AAA OG   1 
ATOM   2984 H H    . SER A 1 180 ? -39.331 -9.054  18.802 1.000 52.910  ? 1441 SER AAA H    1 
ATOM   2985 H HA   . SER A 1 180 ? -40.902 -8.249  16.566 1.000 52.700  ? 1441 SER AAA HA   1 
ATOM   2986 H HB2  . SER A 1 180 ? -42.770 -8.620  17.967 1.000 55.730  ? 1441 SER AAA HB2  1 
ATOM   2987 H HB3  . SER A 1 180 ? -41.800 -9.886  17.878 1.000 55.730  ? 1441 SER AAA HB3  1 
ATOM   2988 H HG   . SER A 1 180 ? -42.339 -9.437  19.964 0.000 60.390  ? 1441 SER AAA HG   1 
ATOM   2989 N N    . SER A 1 181 ? -40.338 -5.988  18.776 1.000 45.840  ? 1442 SER AAA N    1 
ATOM   2990 C CA   . SER A 1 181 ? -40.428 -4.527  19.083 1.000 49.200  ? 1442 SER AAA CA   1 
ATOM   2991 C C    . SER A 1 181 ? -39.299 -4.073  20.026 1.000 51.200  ? 1442 SER AAA C    1 
ATOM   2992 O O    . SER A 1 181 ? -38.626 -4.949  20.561 1.000 49.640  ? 1442 SER AAA O    1 
ATOM   2993 C CB   . SER A 1 181 ? -41.767 -4.194  19.697 1.000 55.520  ? 1442 SER AAA CB   1 
ATOM   2994 O OG   . SER A 1 181 ? -41.710 -4.246  21.120 1.000 52.920  ? 1442 SER AAA OG   1 
ATOM   2995 H H    . SER A 1 181 ? -39.699 -6.564  19.306 1.000 45.840  ? 1442 SER AAA H    1 
ATOM   2996 H HA   . SER A 1 181 ? -40.322 -4.026  18.230 1.000 49.200  ? 1442 SER AAA HA   1 
ATOM   2997 H HB2  . SER A 1 181 ? -42.038 -3.290  19.417 1.000 55.520  ? 1442 SER AAA HB2  1 
ATOM   2998 H HB3  . SER A 1 181 ? -42.440 -4.836  19.377 1.000 55.520  ? 1442 SER AAA HB3  1 
ATOM   2999 H HG   . SER A 1 181 ? -42.475 -4.055  21.427 0.000 52.920  ? 1442 SER AAA HG   1 
ATOM   3000 N N    . VAL A 1 182 ? -39.169 -2.760  20.287 1.000 49.080  ? 1443 VAL AAA N    1 
ATOM   3001 C CA   . VAL A 1 182 ? -38.146 -2.171  21.209 1.000 53.290  ? 1443 VAL AAA CA   1 
ATOM   3002 C C    . VAL A 1 182 ? -38.323 -2.722  22.635 1.000 61.050  ? 1443 VAL AAA C    1 
ATOM   3003 O O    . VAL A 1 182 ? -37.303 -2.831  23.372 1.000 62.470  ? 1443 VAL AAA O    1 
ATOM   3004 C CB   . VAL A 1 182 ? -38.152 -0.625  21.217 1.000 51.600  ? 1443 VAL AAA CB   1 
ATOM   3005 C CG1  . VAL A 1 182 ? -37.484 -0.053  19.982 1.000 47.380  ? 1443 VAL AAA CG1  1 
ATOM   3006 C CG2  . VAL A 1 182 ? -39.543 -0.034  21.405 1.000 46.670  ? 1443 VAL AAA CG2  1 
ATOM   3007 H H    . VAL A 1 182 ? -39.819 -2.147  19.816 1.000 49.080  ? 1443 VAL AAA H    1 
ATOM   3008 H HA   . VAL A 1 182 ? -37.262 -2.436  20.897 1.000 53.290  ? 1443 VAL AAA HA   1 
ATOM   3009 H HB   . VAL A 1 182 ? -37.607 -0.334  21.989 1.000 51.600  ? 1443 VAL AAA HB   1 
ATOM   3010 H HG11 . VAL A 1 182 ? -36.560 -0.355  19.943 1.000 47.380  ? 1443 VAL AAA HG11 1 
ATOM   3011 H HG12 . VAL A 1 182 ? -37.507 0.919   20.021 1.000 47.380  ? 1443 VAL AAA HG12 1 
ATOM   3012 H HG13 . VAL A 1 182 ? -37.957 -0.356  19.187 1.000 47.380  ? 1443 VAL AAA HG13 1 
ATOM   3013 H HG21 . VAL A 1 182 ? -40.121 -0.327  20.680 1.000 46.670  ? 1443 VAL AAA HG21 1 
ATOM   3014 H HG22 . VAL A 1 182 ? -39.486 0.937   21.402 1.000 46.670  ? 1443 VAL AAA HG22 1 
ATOM   3015 H HG23 . VAL A 1 182 ? -39.912 -0.334  22.254 1.000 46.670  ? 1443 VAL AAA HG23 1 
ATOM   3016 N N    . ASP A 1 183 ? -39.549 -3.054  23.037 1.000 58.810  ? 1444 ASP AAA N    1 
ATOM   3017 C CA   . ASP A 1 183 ? -39.814 -3.513  24.424 1.000 61.020  ? 1444 ASP AAA CA   1 
ATOM   3018 C C    . ASP A 1 183 ? -39.046 -4.803  24.681 1.000 55.870  ? 1444 ASP AAA C    1 
ATOM   3019 O O    . ASP A 1 183 ? -38.765 -5.047  25.837 1.000 69.980  ? 1444 ASP AAA O    1 
ATOM   3020 C CB   . ASP A 1 183 ? -41.311 -3.675  24.683 1.000 67.690  ? 1444 ASP AAA CB   1 
ATOM   3021 C CG   . ASP A 1 183 ? -42.061 -2.364  24.520 1.000 72.970  ? 1444 ASP AAA CG   1 
ATOM   3022 O OD1  . ASP A 1 183 ? -41.495 -1.307  24.850 1.000 71.060  ? 1444 ASP AAA OD1  1 
ATOM   3023 O OD2  . ASP A 1 183 ? -43.187 -2.405  24.036 1.000 81.660  ? 1444 ASP AAA OD2  1 
ATOM   3024 H H    . ASP A 1 183 ? -40.317 -2.992  22.384 1.000 58.810  ? 1444 ASP AAA H    1 
ATOM   3025 H HA   . ASP A 1 183 ? -39.493 -2.821  25.049 1.000 61.020  ? 1444 ASP AAA HA   1 
ATOM   3026 H HB2  . ASP A 1 183 ? -41.669 -4.321  24.040 1.000 67.690  ? 1444 ASP AAA HB2  1 
ATOM   3027 H HB3  . ASP A 1 183 ? -41.435 -3.993  25.601 1.000 67.690  ? 1444 ASP AAA HB3  1 
ATOM   3028 N N    . GLU A 1 184 ? -38.734 -5.577  23.635 1.000 54.870  ? 1445 GLU AAA N    1 
ATOM   3029 C CA   . GLU A 1 184 ? -37.961 -6.845  23.696 1.000 55.530  ? 1445 GLU AAA CA   1 
ATOM   3030 C C    . GLU A 1 184 ? -36.466 -6.589  23.951 1.000 66.790  ? 1445 GLU AAA C    1 
ATOM   3031 O O    . GLU A 1 184 ? -35.740 -7.562  24.295 1.000 58.590  ? 1445 GLU AAA O    1 
ATOM   3032 C CB   . GLU A 1 184 ? -38.085 -7.580  22.366 1.000 69.500  ? 1445 GLU AAA CB   1 
ATOM   3033 C CG   . GLU A 1 184 ? -39.467 -8.122  22.123 1.000 78.860  ? 1445 GLU AAA CG   1 
ATOM   3034 C CD   . GLU A 1 184 ? -39.845 -9.000  23.292 1.000 93.890  ? 1445 GLU AAA CD   1 
ATOM   3035 O OE1  . GLU A 1 184 ? -38.944 -9.750  23.772 1.000 103.570 ? 1445 GLU AAA OE1  1 
ATOM   3036 O OE2  . GLU A 1 184 ? -40.993 -8.877  23.766 1.000 98.660  ? 1445 GLU AAA OE2  1 
ATOM   3037 H H    . GLU A 1 184 ? -39.066 -5.245  22.741 1.000 54.870  ? 1445 GLU AAA H    1 
ATOM   3038 H HA   . GLU A 1 184 ? -38.304 -7.384  24.446 1.000 55.530  ? 1445 GLU AAA HA   1 
ATOM   3039 H HB2  . GLU A 1 184 ? -37.851 -6.960  21.644 1.000 69.500  ? 1445 GLU AAA HB2  1 
ATOM   3040 H HB3  . GLU A 1 184 ? -37.443 -8.320  22.358 1.000 69.500  ? 1445 GLU AAA HB3  1 
ATOM   3041 H HG2  . GLU A 1 184 ? -40.089 -7.371  22.019 1.000 78.860  ? 1445 GLU AAA HG2  1 
ATOM   3042 H HG3  . GLU A 1 184 ? -39.468 -8.622  21.279 1.000 78.860  ? 1445 GLU AAA HG3  1 
ATOM   3043 N N    . LEU A 1 185 ? -35.987 -5.361  23.722 1.000 64.920  ? 1446 LEU AAA N    1 
ATOM   3044 C CA   . LEU A 1 185 ? -34.544 -5.037  23.841 1.000 59.440  ? 1446 LEU AAA CA   1 
ATOM   3045 C C    . LEU A 1 185 ? -34.120 -5.266  25.284 1.000 56.640  ? 1446 LEU AAA C    1 
ATOM   3046 O O    . LEU A 1 185 ? -33.071 -5.875  25.500 1.000 62.600  ? 1446 LEU AAA O    1 
ATOM   3047 C CB   . LEU A 1 185 ? -34.284 -3.585  23.431 1.000 56.680  ? 1446 LEU AAA CB   1 
ATOM   3048 C CG   . LEU A 1 185 ? -34.062 -3.372  21.941 1.000 57.660  ? 1446 LEU AAA CG   1 
ATOM   3049 C CD1  . LEU A 1 185 ? -34.175 -1.901  21.604 1.000 60.630  ? 1446 LEU AAA CD1  1 
ATOM   3050 C CD2  . LEU A 1 185 ? -32.724 -3.943  21.499 1.000 52.650  ? 1446 LEU AAA CD2  1 
ATOM   3051 H H    . LEU A 1 185 ? -36.635 -4.632  23.459 1.000 64.920  ? 1446 LEU AAA H    1 
ATOM   3052 H HA   . LEU A 1 185 ? -34.038 -5.644  23.253 1.000 59.440  ? 1446 LEU AAA HA   1 
ATOM   3053 H HB2  . LEU A 1 185 ? -35.047 -3.043  23.717 1.000 56.680  ? 1446 LEU AAA HB2  1 
ATOM   3054 H HB3  . LEU A 1 185 ? -33.497 -3.265  23.916 1.000 56.680  ? 1446 LEU AAA HB3  1 
ATOM   3055 H HG   . LEU A 1 185 ? -34.775 -3.854  21.453 1.000 57.660  ? 1446 LEU AAA HG   1 
ATOM   3056 H HD11 . LEU A 1 185 ? -35.061 -1.580  21.845 1.000 60.630  ? 1446 LEU AAA HD11 1 
ATOM   3057 H HD12 . LEU A 1 185 ? -34.031 -1.775  20.650 1.000 60.630  ? 1446 LEU AAA HD12 1 
ATOM   3058 H HD13 . LEU A 1 185 ? -33.504 -1.402  22.101 1.000 60.630  ? 1446 LEU AAA HD13 1 
ATOM   3059 H HD21 . LEU A 1 185 ? -32.006 -3.503  21.987 1.000 52.650  ? 1446 LEU AAA HD21 1 
ATOM   3060 H HD22 . LEU A 1 185 ? -32.607 -3.795  20.544 1.000 52.650  ? 1446 LEU AAA HD22 1 
ATOM   3061 H HD23 . LEU A 1 185 ? -32.702 -4.898  21.683 1.000 52.650  ? 1446 LEU AAA HD23 1 
ATOM   3062 N N    . GLU A 1 186 ? -34.929 -4.789  26.222 1.000 56.370  ? 1447 GLU AAA N    1 
ATOM   3063 C CA   . GLU A 1 186 ? -34.654 -4.924  27.669 1.000 59.890  ? 1447 GLU AAA CA   1 
ATOM   3064 C C    . GLU A 1 186 ? -34.741 -6.408  28.075 1.000 53.640  ? 1447 GLU AAA C    1 
ATOM   3065 O O    . GLU A 1 186 ? -33.907 -6.848  28.870 1.000 52.340  ? 1447 GLU AAA O    1 
ATOM   3066 C CB   . GLU A 1 186 ? -35.602 -3.998  28.417 1.000 69.450  ? 1447 GLU AAA CB   1 
ATOM   3067 C CG   . GLU A 1 186 ? -35.256 -3.862  29.880 1.000 86.040  ? 1447 GLU AAA CG   1 
ATOM   3068 C CD   . GLU A 1 186 ? -36.451 -3.830  30.818 1.000 95.120  ? 1447 GLU AAA CD   1 
ATOM   3069 O OE1  . GLU A 1 186 ? -36.293 -3.254  31.908 1.000 92.710  ? 1447 GLU AAA OE1  1 
ATOM   3070 O OE2  . GLU A 1 186 ? -37.523 -4.401  30.470 1.000 96.030  ? 1447 GLU AAA OE2  1 
ATOM   3071 H H    . GLU A 1 186 ? -35.768 -4.314  25.923 1.000 56.370  ? 1447 GLU AAA H    1 
ATOM   3072 H HA   . GLU A 1 186 ? -33.740 -4.602  27.845 1.000 59.890  ? 1447 GLU AAA HA   1 
ATOM   3073 H HB2  . GLU A 1 186 ? -35.572 -3.114  27.995 1.000 69.450  ? 1447 GLU AAA HB2  1 
ATOM   3074 H HB3  . GLU A 1 186 ? -36.513 -4.350  28.333 1.000 69.450  ? 1447 GLU AAA HB3  1 
ATOM   3075 H HG2  . GLU A 1 186 ? -34.679 -4.611  30.141 1.000 86.040  ? 1447 GLU AAA HG2  1 
ATOM   3076 H HG3  . GLU A 1 186 ? -34.741 -3.037  30.009 1.000 86.040  ? 1447 GLU AAA HG3  1 
ATOM   3077 N N    . GLN A 1 187 ? -35.719 -7.163  27.572 1.000 57.000  ? 1448 GLN AAA N    1 
ATOM   3078 C CA   . GLN A 1 187 ? -35.791 -8.637  27.783 1.000 61.020  ? 1448 GLN AAA CA   1 
ATOM   3079 C C    . GLN A 1 187 ? -34.456 -9.246  27.360 1.000 61.860  ? 1448 GLN AAA C    1 
ATOM   3080 O O    . GLN A 1 187 ? -33.894 -10.057 28.114 1.000 62.030  ? 1448 GLN AAA O    1 
ATOM   3081 C CB   . GLN A 1 187 ? -36.875 -9.317  26.937 1.000 66.370  ? 1448 GLN AAA CB   1 
ATOM   3082 C CG   . GLN A 1 187 ? -38.161 -9.602  27.686 1.000 71.660  ? 1448 GLN AAA CG   1 
ATOM   3083 C CD   . GLN A 1 187 ? -38.729 -8.313  28.209 1.000 77.970  ? 1448 GLN AAA CD   1 
ATOM   3084 O OE1  . GLN A 1 187 ? -38.908 -7.363  27.452 1.000 88.520  ? 1448 GLN AAA OE1  1 
ATOM   3085 N NE2  . GLN A 1 187 ? -38.985 -8.263  29.508 1.000 70.330  ? 1448 GLN AAA NE2  1 
ATOM   3086 H H    . GLN A 1 187 ? -36.437 -6.708  27.026 1.000 57.000  ? 1448 GLN AAA H    1 
ATOM   3087 H HA   . GLN A 1 187 ? -35.938 -8.808  28.742 1.000 61.020  ? 1448 GLN AAA HA   1 
ATOM   3088 H HB2  . GLN A 1 187 ? -37.078 -8.742  26.169 1.000 66.370  ? 1448 GLN AAA HB2  1 
ATOM   3089 H HB3  . GLN A 1 187 ? -36.517 -10.162 26.592 1.000 66.370  ? 1448 GLN AAA HB3  1 
ATOM   3090 H HG2  . GLN A 1 187 ? -38.798 -10.038 27.080 1.000 71.660  ? 1448 GLN AAA HG2  1 
ATOM   3091 H HG3  . GLN A 1 187 ? -37.974 -10.220 28.424 1.000 71.660  ? 1448 GLN AAA HG3  1 
ATOM   3092 H HE21 . GLN A 1 187 ? -39.320 -7.527  29.865 0.000 70.330  ? 1448 GLN AAA HE21 1 
ATOM   3093 H HE22 . GLN A 1 187 ? -38.821 -8.966  30.019 0.000 70.330  ? 1448 GLN AAA HE22 1 
ATOM   3094 N N    . GLN A 1 188 ? -33.970 -8.836  26.191 1.000 59.730  ? 1449 GLN AAA N    1 
ATOM   3095 C CA   . GLN A 1 188 ? -32.889 -9.528  25.453 1.000 60.810  ? 1449 GLN AAA CA   1 
ATOM   3096 C C    . GLN A 1 188 ? -31.507 -8.998  25.869 1.000 56.120  ? 1449 GLN AAA C    1 
ATOM   3097 O O    . GLN A 1 188 ? -30.500 -9.637  25.520 1.000 52.130  ? 1449 GLN AAA O    1 
ATOM   3098 C CB   . GLN A 1 188 ? -33.186 -9.354  23.967 1.000 70.170  ? 1449 GLN AAA CB   1 
ATOM   3099 C CG   . GLN A 1 188 ? -34.250 -10.311 23.459 1.000 66.730  ? 1449 GLN AAA CG   1 
ATOM   3100 C CD   . GLN A 1 188 ? -33.531 -11.598 23.181 1.000 72.290  ? 1449 GLN AAA CD   1 
ATOM   3101 O OE1  . GLN A 1 188 ? -33.203 -12.334 24.103 1.000 81.900  ? 1449 GLN AAA OE1  1 
ATOM   3102 N NE2  . GLN A 1 188 ? -33.182 -11.814 21.924 1.000 68.900  ? 1449 GLN AAA NE2  1 
ATOM   3103 H H    . GLN A 1 188 ? -34.376 -7.999  25.799 1.000 59.730  ? 1449 GLN AAA H    1 
ATOM   3104 H HA   . GLN A 1 188 ? -32.925 -10.487 25.674 1.000 60.810  ? 1449 GLN AAA HA   1 
ATOM   3105 H HB2  . GLN A 1 188 ? -33.477 -8.431  23.813 1.000 70.170  ? 1449 GLN AAA HB2  1 
ATOM   3106 H HB3  . GLN A 1 188 ? -32.356 -9.493  23.465 1.000 70.170  ? 1449 GLN AAA HB3  1 
ATOM   3107 H HG2  . GLN A 1 188 ? -34.947 -10.411 24.142 1.000 66.730  ? 1449 GLN AAA HG2  1 
ATOM   3108 H HG3  . GLN A 1 188 ? -34.667 -9.933  22.655 1.000 66.730  ? 1449 GLN AAA HG3  1 
ATOM   3109 H HE21 . GLN A 1 188 ? -32.756 -12.557 21.705 0.000 68.900  ? 1449 GLN AAA HE21 1 
ATOM   3110 H HE22 . GLN A 1 188 ? -33.375 -11.216 21.302 0.000 68.900  ? 1449 GLN AAA HE22 1 
ATOM   3111 N N    . ARG A 1 189 ? -31.463 -7.900  26.626 1.000 54.580  ? 1450 ARG AAA N    1 
ATOM   3112 C CA   . ARG A 1 189 ? -30.233 -7.121  26.910 1.000 53.600  ? 1450 ARG AAA CA   1 
ATOM   3113 C C    . ARG A 1 189 ? -29.125 -8.015  27.490 1.000 49.390  ? 1450 ARG AAA C    1 
ATOM   3114 O O    . ARG A 1 189 ? -27.969 -7.911  27.042 1.000 48.700  ? 1450 ARG AAA O    1 
ATOM   3115 C CB   . ARG A 1 189 ? -30.572 -5.982  27.870 1.000 57.740  ? 1450 ARG AAA CB   1 
ATOM   3116 C CG   . ARG A 1 189 ? -29.380 -5.100  28.216 1.000 65.440  ? 1450 ARG AAA CG   1 
ATOM   3117 C CD   . ARG A 1 189 ? -29.657 -4.230  29.417 1.000 62.920  ? 1450 ARG AAA CD   1 
ATOM   3118 N NE   . ARG A 1 189 ? -30.030 -5.018  30.570 1.000 59.570  ? 1450 ARG AAA NE   1 
ATOM   3119 C CZ   . ARG A 1 189 ? -30.823 -4.581  31.539 1.000 64.470  ? 1450 ARG AAA CZ   1 
ATOM   3120 N NH1  . ARG A 1 189 ? -31.360 -3.373  31.486 1.000 66.810  ? 1450 ARG AAA NH1  1 
ATOM   3121 N NH2  . ARG A 1 189 ? -31.090 -5.360  32.561 1.000 58.130  ? 1450 ARG AAA NH2  1 
ATOM   3122 H H    . ARG A 1 189 ? -32.341 -7.597  27.023 1.000 54.580  ? 1450 ARG AAA H    1 
ATOM   3123 H HA   . ARG A 1 189 ? -29.901 -6.741  26.064 1.000 53.600  ? 1450 ARG AAA HA   1 
ATOM   3124 H HB2  . ARG A 1 189 ? -31.271 -5.429  27.463 1.000 57.740  ? 1450 ARG AAA HB2  1 
ATOM   3125 H HB3  . ARG A 1 189 ? -30.935 -6.367  28.695 1.000 57.740  ? 1450 ARG AAA HB3  1 
ATOM   3126 H HG2  . ARG A 1 189 ? -28.601 -5.667  28.400 1.000 65.440  ? 1450 ARG AAA HG2  1 
ATOM   3127 H HG3  . ARG A 1 189 ? -29.165 -4.531  27.447 1.000 65.440  ? 1450 ARG AAA HG3  1 
ATOM   3128 H HD2  . ARG A 1 189 ? -28.857 -3.702  29.624 1.000 62.920  ? 1450 ARG AAA HD2  1 
ATOM   3129 H HD3  . ARG A 1 189 ? -30.379 -3.602  29.201 1.000 62.920  ? 1450 ARG AAA HD3  1 
ATOM   3130 H HE   . ARG A 1 189 ? -29.714 -5.828  30.630 1.000 59.570  ? 1450 ARG AAA HE   1 
ATOM   3131 H HH11 . ARG A 1 189 ? -31.192 -2.849  30.801 1.000 66.810  ? 1450 ARG AAA HH11 1 
ATOM   3132 H HH12 . ARG A 1 189 ? -31.884 -3.098  32.136 1.000 66.810  ? 1450 ARG AAA HH12 1 
ATOM   3133 H HH21 . ARG A 1 189 ? -30.742 -6.168  32.599 1.000 58.130  ? 1450 ARG AAA HH21 1 
ATOM   3134 H HH22 . ARG A 1 189 ? -31.616 -5.072  33.206 1.000 58.130  ? 1450 ARG AAA HH22 1 
ATOM   3135 N N    . ASP A 1 190 ? -29.430 -8.840  28.481 1.000 45.000  ? 1451 ASP AAA N    1 
ATOM   3136 C CA   . ASP A 1 190 ? -28.376 -9.537  29.266 1.000 47.340  ? 1451 ASP AAA CA   1 
ATOM   3137 C C    . ASP A 1 190 ? -27.712 -10.590 28.401 1.000 45.660  ? 1451 ASP AAA C    1 
ATOM   3138 O O    . ASP A 1 190 ? -26.493 -10.752 28.507 1.000 50.560  ? 1451 ASP AAA O    1 
ATOM   3139 C CB   . ASP A 1 190 ? -28.949 -10.185 30.527 1.000 52.840  ? 1451 ASP AAA CB   1 
ATOM   3140 C CG   . ASP A 1 190 ? -29.368 -9.165  31.554 1.000 50.540  ? 1451 ASP AAA CG   1 
ATOM   3141 O OD1  . ASP A 1 190 ? -28.897 -8.005  31.450 1.000 57.800  ? 1451 ASP AAA OD1  1 
ATOM   3142 O OD2  . ASP A 1 190 ? -30.170 -9.530  32.417 1.000 53.770  ? 1451 ASP AAA OD2  1 
ATOM   3143 H H    . ASP A 1 190 ? -30.401 -9.000  28.709 1.000 45.000  ? 1451 ASP AAA H    1 
ATOM   3144 H HA   . ASP A 1 190 ? -27.697 -8.875  29.534 1.000 47.340  ? 1451 ASP AAA HA   1 
ATOM   3145 H HB2  . ASP A 1 190 ? -29.735 -10.711 30.276 1.000 52.840  ? 1451 ASP AAA HB2  1 
ATOM   3146 H HB3  . ASP A 1 190 ? -28.260 -10.757 30.923 1.000 52.840  ? 1451 ASP AAA HB3  1 
ATOM   3147 N N    . GLU A 1 191 ? -28.519 -11.285 27.606 1.000 45.590  ? 1452 GLU AAA N    1 
ATOM   3148 C CA   . GLU A 1 191 ? -28.069 -12.279 26.615 1.000 46.770  ? 1452 GLU AAA CA   1 
ATOM   3149 C C    . GLU A 1 191 ? -27.191 -11.549 25.588 1.000 51.030  ? 1452 GLU AAA C    1 
ATOM   3150 O O    . GLU A 1 191 ? -26.076 -12.053 25.272 1.000 52.040  ? 1452 GLU AAA O    1 
ATOM   3151 C CB   . GLU A 1 191 ? -29.318 -12.957 26.047 1.000 52.660  ? 1452 GLU AAA CB   1 
ATOM   3152 C CG   . GLU A 1 191 ? -29.053 -13.965 24.938 1.000 62.030  ? 1452 GLU AAA CG   1 
ATOM   3153 C CD   . GLU A 1 191 ? -30.325 -14.394 24.211 1.000 74.050  ? 1452 GLU AAA CD   1 
ATOM   3154 O OE1  . GLU A 1 191 ? -31.373 -14.536 24.880 1.000 83.570  ? 1452 GLU AAA OE1  1 
ATOM   3155 O OE2  . GLU A 1 191 ? -30.279 -14.558 22.979 1.000 72.060  ? 1452 GLU AAA OE2  1 
ATOM   3156 H H    . GLU A 1 191 ? -29.507 -11.102 27.706 1.000 45.590  ? 1452 GLU AAA H    1 
ATOM   3157 H HA   . GLU A 1 191 ? -27.534 -12.963 27.080 1.000 46.770  ? 1452 GLU AAA HA   1 
ATOM   3158 H HB2  . GLU A 1 191 ? -29.780 -13.421 26.776 1.000 52.660  ? 1452 GLU AAA HB2  1 
ATOM   3159 H HB3  . GLU A 1 191 ? -29.915 -12.265 25.693 1.000 52.660  ? 1452 GLU AAA HB3  1 
ATOM   3160 H HG2  . GLU A 1 191 ? -28.427 -13.571 24.293 1.000 62.030  ? 1452 GLU AAA HG2  1 
ATOM   3161 H HG3  . GLU A 1 191 ? -28.617 -14.755 25.324 1.000 62.030  ? 1452 GLU AAA HG3  1 
ATOM   3162 N N    . ILE A 1 192 ? -27.643 -10.394 25.094 1.000 46.020  ? 1453 ILE AAA N    1 
ATOM   3163 C CA   . ILE A 1 192 ? -26.904 -9.659  24.032 1.000 45.530  ? 1453 ILE AAA CA   1 
ATOM   3164 C C    . ILE A 1 192 ? -25.545 -9.199  24.573 1.000 43.300  ? 1453 ILE AAA C    1 
ATOM   3165 O O    . ILE A 1 192 ? -24.523 -9.544  23.959 1.000 47.660  ? 1453 ILE AAA O    1 
ATOM   3166 C CB   . ILE A 1 192 ? -27.735 -8.514  23.440 1.000 49.060  ? 1453 ILE AAA CB   1 
ATOM   3167 C CG1  . ILE A 1 192 ? -28.919 -9.083  22.644 1.000 51.500  ? 1453 ILE AAA CG1  1 
ATOM   3168 C CG2  . ILE A 1 192 ? -26.846 -7.632  22.561 1.000 49.070  ? 1453 ILE AAA CG2  1 
ATOM   3169 C CD1  . ILE A 1 192 ? -29.969 -8.067  22.288 1.000 48.750  ? 1453 ILE AAA CD1  1 
ATOM   3170 H H    . ILE A 1 192 ? -28.507 -10.009 25.449 1.000 46.020  ? 1453 ILE AAA H    1 
ATOM   3171 H HA   . ILE A 1 192 ? -26.744 -10.270 23.290 1.000 45.530  ? 1453 ILE AAA HA   1 
ATOM   3172 H HB   . ILE A 1 192 ? -28.062 -7.965  24.195 1.000 49.060  ? 1453 ILE AAA HB   1 
ATOM   3173 H HG12 . ILE A 1 192 ? -28.578 -9.483  21.816 1.000 51.500  ? 1453 ILE AAA HG12 1 
ATOM   3174 H HG13 . ILE A 1 192 ? -29.340 -9.795  23.172 1.000 51.500  ? 1453 ILE AAA HG13 1 
ATOM   3175 H HG21 . ILE A 1 192 ? -26.124 -7.258  23.096 1.000 49.070  ? 1453 ILE AAA HG21 1 
ATOM   3176 H HG22 . ILE A 1 192 ? -27.373 -6.904  22.188 1.000 49.070  ? 1453 ILE AAA HG22 1 
ATOM   3177 H HG23 . ILE A 1 192 ? -26.471 -8.163  21.838 1.000 49.070  ? 1453 ILE AAA HG23 1 
ATOM   3178 H HD11 . ILE A 1 192 ? -30.334 -7.677  23.101 1.000 48.750  ? 1453 ILE AAA HD11 1 
ATOM   3179 H HD12 . ILE A 1 192 ? -30.683 -8.498  21.788 1.000 48.750  ? 1453 ILE AAA HD12 1 
ATOM   3180 H HD13 . ILE A 1 192 ? -29.572 -7.365  21.744 1.000 48.750  ? 1453 ILE AAA HD13 1 
ATOM   3181 N N    . VAL A 1 193 ? -25.496 -8.509  25.704 1.000 40.960  ? 1454 VAL AAA N    1 
ATOM   3182 C CA   . VAL A 1 193 ? -24.204 -7.992  26.238 1.000 41.490  ? 1454 VAL AAA CA   1 
ATOM   3183 C C    . VAL A 1 193 ? -23.280 -9.167  26.592 1.000 45.810  ? 1454 VAL AAA C    1 
ATOM   3184 O O    . VAL A 1 193 ? -22.057 -9.037  26.360 1.000 49.260  ? 1454 VAL AAA O    1 
ATOM   3185 C CB   . VAL A 1 193 ? -24.393 -7.007  27.403 1.000 39.560  ? 1454 VAL AAA CB   1 
ATOM   3186 C CG1  . VAL A 1 193 ? -24.957 -7.655  28.645 1.000 46.450  ? 1454 VAL AAA CG1  1 
ATOM   3187 C CG2  . VAL A 1 193 ? -23.094 -6.290  27.712 1.000 42.990  ? 1454 VAL AAA CG2  1 
ATOM   3188 H H    . VAL A 1 193 ? -26.348 -8.329  26.216 1.000 40.960  ? 1454 VAL AAA H    1 
ATOM   3189 H HA   . VAL A 1 193 ? -23.771 -7.467  25.541 1.000 41.490  ? 1454 VAL AAA HA   1 
ATOM   3190 H HB   . VAL A 1 193 ? -25.055 -6.332  27.112 1.000 39.560  ? 1454 VAL AAA HB   1 
ATOM   3191 H HG11 . VAL A 1 193 ? -25.827 -8.042  28.443 1.000 46.450  ? 1454 VAL AAA HG11 1 
ATOM   3192 H HG12 . VAL A 1 193 ? -25.054 -6.986  29.345 1.000 46.450  ? 1454 VAL AAA HG12 1 
ATOM   3193 H HG13 . VAL A 1 193 ? -24.354 -8.356  28.948 1.000 46.450  ? 1454 VAL AAA HG13 1 
ATOM   3194 H HG21 . VAL A 1 193 ? -22.414 -6.941  27.957 1.000 42.990  ? 1454 VAL AAA HG21 1 
ATOM   3195 H HG22 . VAL A 1 193 ? -23.232 -5.671  28.450 1.000 42.990  ? 1454 VAL AAA HG22 1 
ATOM   3196 H HG23 . VAL A 1 193 ? -22.801 -5.796  26.927 1.000 42.990  ? 1454 VAL AAA HG23 1 
ATOM   3197 N N    . SER A 1 194 ? -23.810 -10.280 27.102 1.000 41.600  ? 1455 SER AAA N    1 
ATOM   3198 C CA   . SER A 1 194 ? -22.986 -11.485 27.370 1.000 42.480  ? 1455 SER AAA CA   1 
ATOM   3199 C C    . SER A 1 194 ? -22.382 -11.960 26.065 1.000 39.260  ? 1455 SER AAA C    1 
ATOM   3200 O O    . SER A 1 194 ? -21.211 -12.285 26.078 1.000 44.750  ? 1455 SER AAA O    1 
ATOM   3201 C CB   . SER A 1 194 ? -23.757 -12.605 27.999 1.000 45.290  ? 1455 SER AAA CB   1 
ATOM   3202 O OG   . SER A 1 194 ? -23.737 -12.473 29.400 1.000 50.390  ? 1455 SER AAA OG   1 
ATOM   3203 H H    . SER A 1 194 ? -24.798 -10.303 27.311 1.000 41.600  ? 1455 SER AAA H    1 
ATOM   3204 H HA   . SER A 1 194 ? -22.250 -11.224 27.987 1.000 42.480  ? 1455 SER AAA HA   1 
ATOM   3205 H HB2  . SER A 1 194 ? -24.686 -12.583 27.674 1.000 45.290  ? 1455 SER AAA HB2  1 
ATOM   3206 H HB3  . SER A 1 194 ? -23.354 -13.464 27.738 1.000 45.290  ? 1455 SER AAA HB3  1 
ATOM   3207 H HG   . SER A 1 194 ? -24.176 -13.113 29.737 0.000 50.390  ? 1455 SER AAA HG   1 
ATOM   3208 N N    . TYR A 1 195 ? -23.164 -12.008 24.989 1.000 42.930  ? 1456 TYR AAA N    1 
ATOM   3209 C CA   . TYR A 1 195 ? -22.665 -12.494 23.673 1.000 48.340  ? 1456 TYR AAA CA   1 
ATOM   3210 C C    . TYR A 1 195 ? -21.545 -11.567 23.179 1.000 47.840  ? 1456 TYR AAA C    1 
ATOM   3211 O O    . TYR A 1 195 ? -20.492 -12.061 22.797 1.000 48.170  ? 1456 TYR AAA O    1 
ATOM   3212 C CB   . TYR A 1 195 ? -23.784 -12.647 22.631 1.000 52.950  ? 1456 TYR AAA CB   1 
ATOM   3213 C CG   . TYR A 1 195 ? -23.301 -13.185 21.301 1.000 53.000  ? 1456 TYR AAA CG   1 
ATOM   3214 C CD1  . TYR A 1 195 ? -22.864 -14.500 21.145 1.000 58.840  ? 1456 TYR AAA CD1  1 
ATOM   3215 C CD2  . TYR A 1 195 ? -23.239 -12.369 20.194 1.000 50.290  ? 1456 TYR AAA CD2  1 
ATOM   3216 C CE1  . TYR A 1 195 ? -22.387 -14.987 19.928 1.000 57.270  ? 1456 TYR AAA CE1  1 
ATOM   3217 C CE2  . TYR A 1 195 ? -22.786 -12.841 18.970 1.000 57.230  ? 1456 TYR AAA CE2  1 
ATOM   3218 C CZ   . TYR A 1 195 ? -22.354 -14.149 18.824 1.000 61.930  ? 1456 TYR AAA CZ   1 
ATOM   3219 O OH   . TYR A 1 195 ? -21.887 -14.554 17.597 1.000 68.540  ? 1456 TYR AAA OH   1 
ATOM   3220 H H    . TYR A 1 195 ? -24.124 -11.705 25.070 1.000 42.930  ? 1456 TYR AAA H    1 
ATOM   3221 H HA   . TYR A 1 195 ? -22.290 -13.403 23.793 1.000 48.340  ? 1456 TYR AAA HA   1 
ATOM   3222 H HB2  . TYR A 1 195 ? -24.469 -13.245 22.997 1.000 52.950  ? 1456 TYR AAA HB2  1 
ATOM   3223 H HB3  . TYR A 1 195 ? -24.204 -11.772 22.497 1.000 52.950  ? 1456 TYR AAA HB3  1 
ATOM   3224 H HD1  . TYR A 1 195 ? -22.867 -15.079 21.889 1.000 58.840  ? 1456 TYR AAA HD1  1 
ATOM   3225 H HD2  . TYR A 1 195 ? -23.510 -11.469 20.268 1.000 50.290  ? 1456 TYR AAA HD2  1 
ATOM   3226 H HE1  . TYR A 1 195 ? -22.099 -15.882 19.856 1.000 57.270  ? 1456 TYR AAA HE1  1 
ATOM   3227 H HE2  . TYR A 1 195 ? -22.772 -12.254 18.232 1.000 57.230  ? 1456 TYR AAA HE2  1 
ATOM   3228 H HH   . TYR A 1 195 ? -22.353 -15.214 17.308 0.000 68.540  ? 1456 TYR AAA HH   1 
ATOM   3229 N N    . LEU A 1 196 ? -21.778 -10.256 23.183 1.000 47.690  ? 1457 LEU AAA N    1 
ATOM   3230 C CA   . LEU A 1 196 ? -20.785 -9.235  22.760 1.000 47.030  ? 1457 LEU AAA CA   1 
ATOM   3231 C C    . LEU A 1 196 ? -19.503 -9.397  23.588 1.000 47.300  ? 1457 LEU AAA C    1 
ATOM   3232 O O    . LEU A 1 196 ? -18.432 -9.366  22.979 1.000 51.580  ? 1457 LEU AAA O    1 
ATOM   3233 C CB   . LEU A 1 196 ? -21.375 -7.824  22.921 1.000 49.530  ? 1457 LEU AAA CB   1 
ATOM   3234 C CG   . LEU A 1 196 ? -22.652 -7.511  22.128 1.000 51.490  ? 1457 LEU AAA CG   1 
ATOM   3235 C CD1  . LEU A 1 196 ? -22.918 -6.021  22.131 1.000 55.260  ? 1457 LEU AAA CD1  1 
ATOM   3236 C CD2  . LEU A 1 196 ? -22.591 -8.019  20.688 1.000 52.770  ? 1457 LEU AAA CD2  1 
ATOM   3237 H H    . LEU A 1 196 ? -22.690 -9.956  23.496 1.000 47.690  ? 1457 LEU AAA H    1 
ATOM   3238 H HA   . LEU A 1 196 ? -20.569 -9.384  21.810 1.000 47.030  ? 1457 LEU AAA HA   1 
ATOM   3239 H HB2  . LEU A 1 196 ? -21.570 -7.678  23.868 1.000 49.530  ? 1457 LEU AAA HB2  1 
ATOM   3240 H HB3  . LEU A 1 196 ? -20.694 -7.174  22.657 1.000 49.530  ? 1457 LEU AAA HB3  1 
ATOM   3241 H HG   . LEU A 1 196 ? -23.407 -7.972  22.569 1.000 51.490  ? 1457 LEU AAA HG   1 
ATOM   3242 H HD11 . LEU A 1 196 ? -23.028 -5.713  23.047 1.000 55.260  ? 1457 LEU AAA HD11 1 
ATOM   3243 H HD12 . LEU A 1 196 ? -23.728 -5.835  21.625 1.000 55.260  ? 1457 LEU AAA HD12 1 
ATOM   3244 H HD13 . LEU A 1 196 ? -22.167 -5.556  21.722 1.000 55.260  ? 1457 LEU AAA HD13 1 
ATOM   3245 H HD21 . LEU A 1 196 ? -21.843 -7.600  20.227 1.000 52.770  ? 1457 LEU AAA HD21 1 
ATOM   3246 H HD22 . LEU A 1 196 ? -23.421 -7.798  20.230 1.000 52.770  ? 1457 LEU AAA HD22 1 
ATOM   3247 H HD23 . LEU A 1 196 ? -22.470 -8.984  20.689 1.000 52.770  ? 1457 LEU AAA HD23 1 
ATOM   3248 N N    . CYS A 1 197 ? -19.596 -9.573  24.912 1.000 47.710  ? 1458 CYS AAA N    1 
ATOM   3249 C CA   . CYS A 1 197 ? -18.425 -9.625  25.834 1.000 47.690  ? 1458 CYS AAA CA   1 
ATOM   3250 C C    . CYS A 1 197 ? -17.583 -10.856 25.498 1.000 45.470  ? 1458 CYS AAA C    1 
ATOM   3251 O O    . CYS A 1 197 ? -16.363 -10.741 25.389 1.000 48.320  ? 1458 CYS AAA O    1 
ATOM   3252 C CB   . CYS A 1 197 ? -18.845 -9.647  27.305 1.000 55.230  ? 1458 CYS AAA CB   1 
ATOM   3253 S SG   . CYS A 1 197 ? -17.531 -9.268  28.514 1.000 53.860  ? 1458 CYS AAA SG   1 
ATOM   3254 H H    . CYS A 1 197 ? -20.526 -9.675  25.291 1.000 47.710  ? 1458 CYS AAA H    1 
ATOM   3255 H HA   . CYS A 1 197 ? -17.882 -8.817  25.682 1.000 47.690  ? 1458 CYS AAA HA   1 
ATOM   3256 H HB2  . CYS A 1 197 ? -19.564 -8.997  27.443 1.000 55.230  ? 1458 CYS AAA HB2  1 
ATOM   3257 H HB3  . CYS A 1 197 ? -19.196 -10.534 27.525 1.000 55.230  ? 1458 CYS AAA HB3  1 
ATOM   3258 N N    . ASP A 1 198 ? -18.220 -11.999 25.306 1.000 49.040  ? 1459 ASP AAA N    1 
ATOM   3259 C CA   . ASP A 1 198 ? -17.521 -13.268 24.962 1.000 56.440  ? 1459 ASP AAA CA   1 
ATOM   3260 C C    . ASP A 1 198 ? -16.813 -13.214 23.603 1.000 54.340  ? 1459 ASP AAA C    1 
ATOM   3261 O O    . ASP A 1 198 ? -15.964 -14.052 23.388 1.000 54.300  ? 1459 ASP AAA O    1 
ATOM   3262 C CB   . ASP A 1 198 ? -18.479 -14.455 24.889 1.000 54.950  ? 1459 ASP AAA CB   1 
ATOM   3263 C CG   . ASP A 1 198 ? -18.843 -14.970 26.257 1.000 67.170  ? 1459 ASP AAA CG   1 
ATOM   3264 O OD1  . ASP A 1 198 ? -18.069 -14.712 27.218 1.000 69.720  ? 1459 ASP AAA OD1  1 
ATOM   3265 O OD2  . ASP A 1 198 ? -19.896 -15.602 26.349 1.000 82.070  ? 1459 ASP AAA OD2  1 
ATOM   3266 H H    . ASP A 1 198 ? -19.226 -12.000 25.399 1.000 49.040  ? 1459 ASP AAA H    1 
ATOM   3267 H HA   . ASP A 1 198 ? -16.827 -13.437 25.642 1.000 56.440  ? 1459 ASP AAA HA   1 
ATOM   3268 H HB2  . ASP A 1 198 ? -19.298 -14.166 24.437 1.000 54.950  ? 1459 ASP AAA HB2  1 
ATOM   3269 H HB3  . ASP A 1 198 ? -18.043 -15.176 24.391 1.000 54.950  ? 1459 ASP AAA HB3  1 
ATOM   3270 N N    . LEU A 1 199 ? -17.191 -12.349 22.669 1.000 54.790  ? 1460 LEU AAA N    1 
ATOM   3271 C CA   . LEU A 1 199 ? -16.484 -12.324 21.367 1.000 49.830  ? 1460 LEU AAA CA   1 
ATOM   3272 C C    . LEU A 1 199 ? -15.141 -11.618 21.552 1.000 50.310  ? 1460 LEU AAA C    1 
ATOM   3273 O O    . LEU A 1 199 ? -14.348 -11.641 20.611 1.000 57.170  ? 1460 LEU AAA O    1 
ATOM   3274 C CB   . LEU A 1 199 ? -17.334 -11.602 20.329 1.000 50.890  ? 1460 LEU AAA CB   1 
ATOM   3275 C CG   . LEU A 1 199 ? -18.649 -12.272 19.966 1.000 50.040  ? 1460 LEU AAA CG   1 
ATOM   3276 C CD1  . LEU A 1 199 ? -19.449 -11.347 19.071 1.000 47.730  ? 1460 LEU AAA CD1  1 
ATOM   3277 C CD2  . LEU A 1 199 ? -18.426 -13.621 19.301 1.000 49.420  ? 1460 LEU AAA CD2  1 
ATOM   3278 H H    . LEU A 1 199 ? -17.953 -11.705 22.828 1.000 54.790  ? 1460 LEU AAA H    1 
ATOM   3279 H HA   . LEU A 1 199 ? -16.323 -13.253 21.081 1.000 49.830  ? 1460 LEU AAA HA   1 
ATOM   3280 H HB2  . LEU A 1 199 ? -17.530 -10.704 20.663 1.000 50.890  ? 1460 LEU AAA HB2  1 
ATOM   3281 H HB3  . LEU A 1 199 ? -16.805 -11.504 19.512 1.000 50.890  ? 1460 LEU AAA HB3  1 
ATOM   3282 H HG   . LEU A 1 199 ? -19.154 -12.429 20.802 1.000 50.040  ? 1460 LEU AAA HG   1 
ATOM   3283 H HD11 . LEU A 1 199 ? -19.625 -10.513 19.541 1.000 47.730  ? 1460 LEU AAA HD11 1 
ATOM   3284 H HD12 . LEU A 1 199 ? -20.292 -11.772 18.835 1.000 47.730  ? 1460 LEU AAA HD12 1 
ATOM   3285 H HD13 . LEU A 1 199 ? -18.943 -11.161 18.261 1.000 47.730  ? 1460 LEU AAA HD13 1 
ATOM   3286 H HD21 . LEU A 1 199 ? -17.908 -13.500 18.486 1.000 49.420  ? 1460 LEU AAA HD21 1 
ATOM   3287 H HD22 . LEU A 1 199 ? -19.286 -14.022 19.083 1.000 49.420  ? 1460 LEU AAA HD22 1 
ATOM   3288 H HD23 . LEU A 1 199 ? -17.941 -14.206 19.909 1.000 49.420  ? 1460 LEU AAA HD23 1 
ATOM   3289 N N    . ALA A 1 200 ? -14.910 -10.967 22.694 1.000 48.570  ? 1461 ALA AAA N    1 
ATOM   3290 C CA   . ALA A 1 200 ? -13.724 -10.108 22.888 1.000 50.820  ? 1461 ALA AAA CA   1 
ATOM   3291 C C    . ALA A 1 200 ? -12.709 -10.852 23.738 1.000 57.210  ? 1461 ALA AAA C    1 
ATOM   3292 O O    . ALA A 1 200 ? -13.089 -11.703 24.540 1.000 59.820  ? 1461 ALA AAA O    1 
ATOM   3293 C CB   . ALA A 1 200 ? -14.089 -8.782  23.519 1.000 51.260  ? 1461 ALA AAA CB   1 
ATOM   3294 H H    . ALA A 1 200 ? -15.573 -11.069 23.449 1.000 48.570  ? 1461 ALA AAA H    1 
ATOM   3295 H HA   . ALA A 1 200 ? -13.325 -9.921  22.006 1.000 50.820  ? 1461 ALA AAA HA   1 
ATOM   3296 H HB1  . ALA A 1 200 ? -13.289 -8.245  23.632 1.000 51.260  ? 1461 ALA AAA HB1  1 
ATOM   3297 H HB2  . ALA A 1 200 ? -14.715 -8.311  22.946 1.000 51.260  ? 1461 ALA AAA HB2  1 
ATOM   3298 H HB3  . ALA A 1 200 ? -14.499 -8.937  24.387 1.000 51.260  ? 1461 ALA AAA HB3  1 
ATOM   3299 N N    . PRO A 1 201 ? -11.408 -10.495 23.619 1.000 60.520  ? 1462 PRO AAA N    1 
ATOM   3300 C CA   . PRO A 1 201 ? -10.374 -11.050 24.491 1.000 62.420  ? 1462 PRO AAA CA   1 
ATOM   3301 C C    . PRO A 1 201 ? -10.179 -10.314 25.837 1.000 62.980  ? 1462 PRO AAA C    1 
ATOM   3302 O O    . PRO A 1 201 ? -10.353 -9.113  25.920 1.000 56.150  ? 1462 PRO AAA O    1 
ATOM   3303 C CB   . PRO A 1 201 ? -9.157  -10.932 23.558 1.000 59.570  ? 1462 PRO AAA CB   1 
ATOM   3304 C CG   . PRO A 1 201 ? -9.369  -9.605  22.847 1.000 59.970  ? 1462 PRO AAA CG   1 
ATOM   3305 C CD   . PRO A 1 201 ? -10.865 -9.528  22.643 1.000 58.680  ? 1462 PRO AAA CD   1 
ATOM   3306 H HA   . PRO A 1 201 ? -10.586 -11.997 24.689 1.000 62.420  ? 1462 PRO AAA HA   1 
ATOM   3307 H HB2  . PRO A 1 201 ? -8.321  -10.937 24.069 1.000 59.570  ? 1462 PRO AAA HB2  1 
ATOM   3308 H HB3  . PRO A 1 201 ? -9.126  -11.679 22.924 1.000 59.570  ? 1462 PRO AAA HB3  1 
ATOM   3309 H HG2  . PRO A 1 201 ? -9.043  -8.860  23.394 1.000 59.970  ? 1462 PRO AAA HG2  1 
ATOM   3310 H HG3  . PRO A 1 201 ? -8.890  -9.586  21.992 1.000 59.970  ? 1462 PRO AAA HG3  1 
ATOM   3311 H HD2  . PRO A 1 201 ? -11.194 -8.621  22.813 1.000 58.680  ? 1462 PRO AAA HD2  1 
ATOM   3312 H HD3  . PRO A 1 201 ? -11.105 -9.770  21.724 1.000 58.680  ? 1462 PRO AAA HD3  1 
ATOM   3313 N N    . GLU A 1 202 ? -9.831  -11.078 26.878 1.000 69.290  ? 1463 GLU AAA N    1 
ATOM   3314 C CA   . GLU A 1 202 ? -9.296  -10.572 28.172 1.000 77.870  ? 1463 GLU AAA CA   1 
ATOM   3315 C C    . GLU A 1 202 ? -7.802  -10.301 27.987 1.000 76.700  ? 1463 GLU AAA C    1 
ATOM   3316 O O    . GLU A 1 202 ? -7.149  -11.142 27.372 1.000 91.270  ? 1463 GLU AAA O    1 
ATOM   3317 C CB   . GLU A 1 202 ? -9.489  -11.624 29.261 1.000 81.980  ? 1463 GLU AAA CB   1 
ATOM   3318 C CG   . GLU A 1 202 ? -10.911 -12.128 29.404 1.000 84.470  ? 1463 GLU AAA CG   1 
ATOM   3319 C CD   . GLU A 1 202 ? -11.007 -13.410 30.211 1.000 87.170  ? 1463 GLU AAA CD   1 
ATOM   3320 O OE1  . GLU A 1 202 ? -10.499 -14.449 29.729 1.000 90.000  ? 1463 GLU AAA OE1  1 
ATOM   3321 O OE2  . GLU A 1 202 ? -11.566 -13.359 31.329 1.000 84.060  ? 1463 GLU AAA OE2  1 
ATOM   3322 H H    . GLU A 1 202 ? -9.950  -12.073 26.750 1.000 69.290  ? 1463 GLU AAA H    1 
ATOM   3323 H HA   . GLU A 1 202 ? -9.758  -9.731  28.393 1.000 77.870  ? 1463 GLU AAA HA   1 
ATOM   3324 H HB2  . GLU A 1 202 ? -8.910  -12.389 29.062 1.000 81.980  ? 1463 GLU AAA HB2  1 
ATOM   3325 H HB3  . GLU A 1 202 ? -9.211  -11.240 30.118 1.000 81.980  ? 1463 GLU AAA HB3  1 
ATOM   3326 H HG2  . GLU A 1 202 ? -11.453 -11.433 29.835 1.000 84.470  ? 1463 GLU AAA HG2  1 
ATOM   3327 H HG3  . GLU A 1 202 ? -11.286 -12.279 28.510 1.000 84.470  ? 1463 GLU AAA HG3  1 
ATOM   3328 N N    . ALA A 1 203 ? -7.276  -9.195  28.509 1.000 74.440  ? 1464 ALA AAA N    1 
ATOM   3329 C CA   . ALA A 1 203 ? -6.007  -8.556  28.059 1.000 86.440  ? 1464 ALA AAA CA   1 
ATOM   3330 C C    . ALA A 1 203 ? -5.004  -9.523  27.407 1.000 93.050  ? 1464 ALA AAA C    1 
ATOM   3331 O O    . ALA A 1 203 ? -4.058  -9.894  28.086 1.000 106.540 ? 1464 ALA AAA O    1 
ATOM   3332 C CB   . ALA A 1 203 ? -5.370  -7.851  29.240 1.000 78.290  ? 1464 ALA AAA CB   1 
ATOM   3333 H H    . ALA A 1 203 ? -7.796  -8.777  29.267 1.000 74.440  ? 1464 ALA AAA H    1 
ATOM   3334 H HA   . ALA A 1 203 ? -6.222  -7.880  27.374 1.000 86.440  ? 1464 ALA AAA HA   1 
ATOM   3335 H HB1  . ALA A 1 203 ? -4.542  -7.431  28.959 1.000 78.290  ? 1464 ALA AAA HB1  1 
ATOM   3336 H HB2  . ALA A 1 203 ? -5.976  -7.174  29.579 1.000 78.290  ? 1464 ALA AAA HB2  1 
ATOM   3337 H HB3  . ALA A 1 203 ? -5.182  -8.497  29.942 1.000 78.290  ? 1464 ALA AAA HB3  1 
ATOM   3338 N N    . PRO A 1 204 ? -5.046  -9.868  26.081 1.000 111.280 ? 1465 PRO AAA N    1 
ATOM   3339 C CA   . PRO A 1 204 ? -3.984  -10.658 25.440 1.000 112.370 ? 1465 PRO AAA CA   1 
ATOM   3340 C C    . PRO A 1 204 ? -2.679  -9.920  25.130 1.000 112.180 ? 1465 PRO AAA C    1 
ATOM   3341 O O    . PRO A 1 204 ? -1.889  -10.391 24.310 1.000 105.140 ? 1465 PRO AAA O    1 
ATOM   3342 C CB   . PRO A 1 204 ? -4.609  -11.114 24.106 1.000 113.960 ? 1465 PRO AAA CB   1 
ATOM   3343 C CG   . PRO A 1 204 ? -5.538  -9.984  23.753 1.000 122.170 ? 1465 PRO AAA CG   1 
ATOM   3344 C CD   . PRO A 1 204 ? -6.095  -9.540  25.098 1.000 130.210 ? 1465 PRO AAA CD   1 
ATOM   3345 H HA   . PRO A 1 204 ? -3.757  -11.430 26.017 1.000 112.370 ? 1465 PRO AAA HA   1 
ATOM   3346 H HB2  . PRO A 1 204 ? -3.920  -11.246 23.422 1.000 113.960 ? 1465 PRO AAA HB2  1 
ATOM   3347 H HB3  . PRO A 1 204 ? -5.091  -11.961 24.215 1.000 113.960 ? 1465 PRO AAA HB3  1 
ATOM   3348 H HG2  . PRO A 1 204 ? -5.052  -9.260  23.306 1.000 122.170 ? 1465 PRO AAA HG2  1 
ATOM   3349 H HG3  . PRO A 1 204 ? -6.248  -10.291 23.151 1.000 122.170 ? 1465 PRO AAA HG3  1 
ATOM   3350 H HD2  . PRO A 1 204 ? -6.285  -8.579  25.097 1.000 130.210 ? 1465 PRO AAA HD2  1 
ATOM   3351 H HD3  . PRO A 1 204 ? -6.928  -10.013 25.304 1.000 130.210 ? 1465 PRO AAA HD3  1 
ATOM   3352 N N    . PRO A 1 205 ? -2.406  -8.731  25.725 1.000 112.530 ? 1466 PRO AAA N    1 
ATOM   3353 C CA   . PRO A 1 205 ? -1.025  -8.335  26.003 1.000 116.370 ? 1466 PRO AAA CA   1 
ATOM   3354 C C    . PRO A 1 205 ? -0.451  -9.222  27.124 1.000 108.230 ? 1466 PRO AAA C    1 
ATOM   3355 O O    . PRO A 1 205 ? 0.745   -9.346  27.359 1.000 99.970  ? 1466 PRO AAA O    1 
ATOM   3356 C CB   . PRO A 1 205 ? -1.143  -6.853  26.409 1.000 110.290 ? 1466 PRO AAA CB   1 
ATOM   3357 C CG   . PRO A 1 205 ? -2.494  -6.416  25.870 1.000 99.210  ? 1466 PRO AAA CG   1 
ATOM   3358 C CD   . PRO A 1 205 ? -3.356  -7.646  26.026 1.000 100.470 ? 1466 PRO AAA CD   1 
ATOM   3359 H HA   . PRO A 1 205 ? -0.488  -8.418  25.175 1.000 116.370 ? 1466 PRO AAA HA   1 
ATOM   3360 H HB2  . PRO A 1 205 ? -1.100  -6.751  27.383 1.000 110.290 ? 1466 PRO AAA HB2  1 
ATOM   3361 H HB3  . PRO A 1 205 ? -0.417  -6.323  26.018 1.000 110.290 ? 1466 PRO AAA HB3  1 
ATOM   3362 H HG2  . PRO A 1 205 ? -2.846  -5.659  26.383 1.000 99.210  ? 1466 PRO AAA HG2  1 
ATOM   3363 H HG3  . PRO A 1 205 ? -2.423  -6.140  24.932 1.000 99.210  ? 1466 PRO AAA HG3  1 
ATOM   3364 H HD2  . PRO A 1 205 ? -3.717  -7.706  26.935 1.000 100.470 ? 1466 PRO AAA HD2  1 
ATOM   3365 H HD3  . PRO A 1 205 ? -4.110  -7.625  25.401 1.000 100.470 ? 1466 PRO AAA HD3  1 
ATOM   3366 N N    . GLU B 2 1   ? -1.409  -11.144 37.401 1.000 79.110  ? 2    GLU BBB N    1 
ATOM   3367 C CA   . GLU B 2 1   ? -2.740  -10.657 36.980 1.000 75.020  ? 2    GLU BBB CA   1 
ATOM   3368 C C    . GLU B 2 1   ? -3.441  -9.875  38.107 1.000 68.780  ? 2    GLU BBB C    1 
ATOM   3369 O O    . GLU B 2 1   ? -3.598  -8.618  37.942 1.000 70.800  ? 2    GLU BBB O    1 
ATOM   3370 C CB   . GLU B 2 1   ? -3.570  -11.856 36.573 1.000 77.610  ? 2    GLU BBB CB   1 
ATOM   3371 C CG   . GLU B 2 1   ? -3.381  -12.235 35.142 1.000 81.420  ? 2    GLU BBB CG   1 
ATOM   3372 C CD   . GLU B 2 1   ? -4.338  -13.370 34.872 1.000 91.730  ? 2    GLU BBB CD   1 
ATOM   3373 O OE1  . GLU B 2 1   ? -5.310  -13.152 34.140 1.000 106.100 ? 2    GLU BBB OE1  1 
ATOM   3374 O OE2  . GLU B 2 1   ? -4.151  -14.436 35.478 1.000 88.820  ? 2    GLU BBB OE2  1 
ATOM   3375 H H1   . GLU B 2 1   ? -1.387  -12.053 37.347 1.000 79.110  ? 2    GLU BBB H1   1 
ATOM   3376 H H2   . GLU B 2 1   ? -1.241  -10.873 38.307 1.000 79.110  ? 2    GLU BBB H2   1 
ATOM   3377 H H3   . GLU B 2 1   ? -0.736  -10.773 36.826 1.000 79.110  ? 2    GLU BBB H3   1 
ATOM   3378 H HA   . GLU B 2 1   ? -2.624  -10.061 36.204 1.000 75.020  ? 2    GLU BBB HA   1 
ATOM   3379 H HB2  . GLU B 2 1   ? -3.309  -12.619 37.129 1.000 77.610  ? 2    GLU BBB HB2  1 
ATOM   3380 H HB3  . GLU B 2 1   ? -4.516  -11.641 36.711 1.000 77.610  ? 2    GLU BBB HB3  1 
ATOM   3381 H HG2  . GLU B 2 1   ? -3.558  -11.451 34.580 1.000 81.420  ? 2    GLU BBB HG2  1 
ATOM   3382 H HG3  . GLU B 2 1   ? -2.444  -12.490 35.002 1.000 81.420  ? 2    GLU BBB HG3  1 
ATOM   3383 N N    . VAL B 2 2   ? -3.879  -10.569 39.176 1.000 59.620  ? 3    VAL BBB N    1 
ATOM   3384 C CA   . VAL B 2 2   ? -4.507  -9.967  40.401 1.000 62.070  ? 3    VAL BBB CA   1 
ATOM   3385 C C    . VAL B 2 2   ? -3.620  -10.234 41.628 1.000 59.720  ? 3    VAL BBB C    1 
ATOM   3386 O O    . VAL B 2 2   ? -3.329  -11.405 41.913 1.000 61.600  ? 3    VAL BBB O    1 
ATOM   3387 C CB   . VAL B 2 2   ? -5.931  -10.486 40.674 1.000 57.980  ? 3    VAL BBB CB   1 
ATOM   3388 C CG1  . VAL B 2 2   ? -6.512  -9.847  41.920 1.000 66.830  ? 3    VAL BBB CG1  1 
ATOM   3389 C CG2  . VAL B 2 2   ? -6.866  -10.245 39.515 1.000 59.430  ? 3    VAL BBB CG2  1 
ATOM   3390 H H    . VAL B 2 2   ? -3.764  -11.571 39.123 1.000 59.620  ? 3    VAL BBB H    1 
ATOM   3391 H HA   . VAL B 2 2   ? -4.564  -9.003  40.275 1.000 62.070  ? 3    VAL BBB HA   1 
ATOM   3392 H HB   . VAL B 2 2   ? -5.867  -11.465 40.801 1.000 57.980  ? 3    VAL BBB HB   1 
ATOM   3393 H HG11 . VAL B 2 2   ? -5.950  -10.059 42.686 1.000 66.830  ? 3    VAL BBB HG11 1 
ATOM   3394 H HG12 . VAL B 2 2   ? -7.410  -10.189 42.072 1.000 66.830  ? 3    VAL BBB HG12 1 
ATOM   3395 H HG13 . VAL B 2 2   ? -6.549  -8.882  41.803 1.000 66.830  ? 3    VAL BBB HG13 1 
ATOM   3396 H HG21 . VAL B 2 2   ? -6.924  -9.290  39.338 1.000 59.430  ? 3    VAL BBB HG21 1 
ATOM   3397 H HG22 . VAL B 2 2   ? -7.750  -10.589 39.733 1.000 59.430  ? 3    VAL BBB HG22 1 
ATOM   3398 H HG23 . VAL B 2 2   ? -6.528  -10.701 38.725 1.000 59.430  ? 3    VAL BBB HG23 1 
ATOM   3399 N N    . GLN B 2 3   ? -3.250  -9.185  42.360 1.000 57.420  ? 4    GLN BBB N    1 
ATOM   3400 C CA   . GLN B 2 3   ? -2.500  -9.289  43.639 1.000 59.190  ? 4    GLN BBB CA   1 
ATOM   3401 C C    . GLN B 2 3   ? -3.413  -8.832  44.792 1.000 58.620  ? 4    GLN BBB C    1 
ATOM   3402 O O    . GLN B 2 3   ? -4.016  -7.701  44.727 1.000 51.560  ? 4    GLN BBB O    1 
ATOM   3403 C CB   . GLN B 2 3   ? -1.202  -8.479  43.579 1.000 66.250  ? 4    GLN BBB CB   1 
ATOM   3404 C CG   . GLN B 2 3   ? -0.159  -8.907  44.608 1.000 74.250  ? 4    GLN BBB CG   1 
ATOM   3405 C CD   . GLN B 2 3   ? 0.687   -7.763  45.131 1.000 84.590  ? 4    GLN BBB CD   1 
ATOM   3406 O OE1  . GLN B 2 3   ? 0.598   -7.355  46.290 1.000 87.110  ? 4    GLN BBB OE1  1 
ATOM   3407 N NE2  . GLN B 2 3   ? 1.533   -7.223  44.271 1.000 90.170  ? 4    GLN BBB NE2  1 
ATOM   3408 H H    . GLN B 2 3   ? -3.502  -8.272  42.010 1.000 57.420  ? 4    GLN BBB H    1 
ATOM   3409 H HA   . GLN B 2 3   ? -2.253  -10.232 43.781 1.000 59.190  ? 4    GLN BBB HA   1 
ATOM   3410 H HB2  . GLN B 2 3   ? -0.820  -8.569  42.681 1.000 66.250  ? 4    GLN BBB HB2  1 
ATOM   3411 H HB3  . GLN B 2 3   ? -1.418  -7.533  43.719 1.000 66.250  ? 4    GLN BBB HB3  1 
ATOM   3412 H HG2  . GLN B 2 3   ? -0.611  -9.329  45.370 1.000 74.250  ? 4    GLN BBB HG2  1 
ATOM   3413 H HG3  . GLN B 2 3   ? 0.438   -9.572  44.204 1.000 74.250  ? 4    GLN BBB HG3  1 
ATOM   3414 H HE21 . GLN B 2 3   ? 2.051   -6.552  44.522 0.000 90.170  ? 4    GLN BBB HE21 1 
ATOM   3415 H HE22 . GLN B 2 3   ? 1.581   -7.532  43.444 0.000 90.170  ? 4    GLN BBB HE22 1 
ATOM   3416 N N    . LEU B 2 4   ? -3.485  -9.685  45.819 1.000 55.730  ? 5    LEU BBB N    1 
ATOM   3417 C CA   . LEU B 2 4   ? -4.322  -9.533  47.037 1.000 46.670  ? 5    LEU BBB CA   1 
ATOM   3418 C C    . LEU B 2 4   ? -3.384  -9.501  48.241 1.000 45.060  ? 5    LEU BBB C    1 
ATOM   3419 O O    . LEU B 2 4   ? -2.554  -10.384 48.373 1.000 47.630  ? 5    LEU BBB O    1 
ATOM   3420 C CB   . LEU B 2 4   ? -5.295  -10.715 47.100 1.000 43.550  ? 5    LEU BBB CB   1 
ATOM   3421 C CG   . LEU B 2 4   ? -6.314  -10.817 45.957 1.000 47.190  ? 5    LEU BBB CG   1 
ATOM   3422 C CD1  . LEU B 2 4   ? -7.121  -12.110 46.063 1.000 43.100  ? 5    LEU BBB CD1  1 
ATOM   3423 C CD2  . LEU B 2 4   ? -7.236  -9.578  45.895 1.000 46.720  ? 5    LEU BBB CD2  1 
ATOM   3424 H H    . LEU B 2 4   ? -2.899  -10.502 45.723 1.000 55.730  ? 5    LEU BBB H    1 
ATOM   3425 H HA   . LEU B 2 4   ? -4.810  -8.680  46.976 1.000 46.670  ? 5    LEU BBB HA   1 
ATOM   3426 H HB2  . LEU B 2 4   ? -4.773  -11.542 47.116 1.000 43.550  ? 5    LEU BBB HB2  1 
ATOM   3427 H HB3  . LEU B 2 4   ? -5.789  -10.662 47.942 1.000 43.550  ? 5    LEU BBB HB3  1 
ATOM   3428 H HG   . LEU B 2 4   ? -5.815  -10.861 45.104 1.000 47.190  ? 5    LEU BBB HG   1 
ATOM   3429 H HD11 . LEU B 2 4   ? -6.519  -12.873 46.016 1.000 43.100  ? 5    LEU BBB HD11 1 
ATOM   3430 H HD12 . LEU B 2 4   ? -7.760  -12.154 45.331 1.000 43.100  ? 5    LEU BBB HD12 1 
ATOM   3431 H HD13 . LEU B 2 4   ? -7.598  -12.126 46.911 1.000 43.100  ? 5    LEU BBB HD13 1 
ATOM   3432 H HD21 . LEU B 2 4   ? -7.724  -9.494  46.733 1.000 46.720  ? 5    LEU BBB HD21 1 
ATOM   3433 H HD22 . LEU B 2 4   ? -7.866  -9.678  45.160 1.000 46.720  ? 5    LEU BBB HD22 1 
ATOM   3434 H HD23 . LEU B 2 4   ? -6.698  -8.780  45.753 1.000 46.720  ? 5    LEU BBB HD23 1 
ATOM   3435 N N    . VAL B 2 5   ? -3.518  -8.503  49.086 1.000 45.740  ? 6    VAL BBB N    1 
ATOM   3436 C CA   . VAL B 2 5   ? -2.682  -8.358  50.305 1.000 51.770  ? 6    VAL BBB CA   1 
ATOM   3437 C C    . VAL B 2 5   ? -3.596  -8.191  51.527 1.000 52.370  ? 6    VAL BBB C    1 
ATOM   3438 O O    . VAL B 2 5   ? -4.131  -7.078  51.721 1.000 50.180  ? 6    VAL BBB O    1 
ATOM   3439 C CB   . VAL B 2 5   ? -1.744  -7.153  50.142 1.000 56.740  ? 6    VAL BBB CB   1 
ATOM   3440 C CG1  . VAL B 2 5   ? -0.978  -6.883  51.420 1.000 64.900  ? 6    VAL BBB CG1  1 
ATOM   3441 C CG2  . VAL B 2 5   ? -0.796  -7.326  48.965 1.000 57.040  ? 6    VAL BBB CG2  1 
ATOM   3442 H H    . VAL B 2 5   ? -4.224  -7.809  48.888 1.000 45.740  ? 6    VAL BBB H    1 
ATOM   3443 H HA   . VAL B 2 5   ? -2.162  -9.174  50.420 1.000 51.770  ? 6    VAL BBB HA   1 
ATOM   3444 H HB   . VAL B 2 5   ? -2.310  -6.364  49.955 1.000 56.740  ? 6    VAL BBB HB   1 
ATOM   3445 H HG11 . VAL B 2 5   ? -1.604  -6.695  52.141 1.000 64.900  ? 6    VAL BBB HG11 1 
ATOM   3446 H HG12 . VAL B 2 5   ? -0.392  -6.117  51.292 1.000 64.900  ? 6    VAL BBB HG12 1 
ATOM   3447 H HG13 . VAL B 2 5   ? -0.445  -7.664  51.650 1.000 64.900  ? 6    VAL BBB HG13 1 
ATOM   3448 H HG21 . VAL B 2 5   ? -0.251  -8.120  49.101 1.000 57.040  ? 6    VAL BBB HG21 1 
ATOM   3449 H HG22 . VAL B 2 5   ? -0.220  -6.545  48.894 1.000 57.040  ? 6    VAL BBB HG22 1 
ATOM   3450 H HG23 . VAL B 2 5   ? -1.311  -7.424  48.145 1.000 57.040  ? 6    VAL BBB HG23 1 
ATOM   3451 N N    . GLU B 2 6   ? -3.715  -9.225  52.361 1.000 48.040  ? 7    GLU BBB N    1 
ATOM   3452 C CA   . GLU B 2 6   ? -4.434  -9.116  53.655 1.000 54.350  ? 7    GLU BBB CA   1 
ATOM   3453 C C    . GLU B 2 6   ? -3.591  -8.366  54.700 1.000 56.820  ? 7    GLU BBB C    1 
ATOM   3454 O O    . GLU B 2 6   ? -2.374  -8.519  54.711 1.000 62.180  ? 7    GLU BBB O    1 
ATOM   3455 C CB   . GLU B 2 6   ? -4.811  -10.493 54.187 1.000 54.380  ? 7    GLU BBB CB   1 
ATOM   3456 C CG   . GLU B 2 6   ? -5.635  -11.327 53.222 1.000 55.420  ? 7    GLU BBB CG   1 
ATOM   3457 C CD   . GLU B 2 6   ? -4.824  -12.328 52.417 1.000 55.730  ? 7    GLU BBB CD   1 
ATOM   3458 O OE1  . GLU B 2 6   ? -3.608  -12.107 52.307 1.000 48.990  ? 7    GLU BBB OE1  1 
ATOM   3459 O OE2  . GLU B 2 6   ? -5.413  -13.306 51.884 1.000 52.280  ? 7    GLU BBB OE2  1 
ATOM   3460 H H    . GLU B 2 6   ? -3.301  -10.109 52.100 1.000 48.040  ? 7    GLU BBB H    1 
ATOM   3461 H HA   . GLU B 2 6   ? -5.262  -8.603  53.510 1.000 54.350  ? 7    GLU BBB HA   1 
ATOM   3462 H HB2  . GLU B 2 6   ? -3.988  -10.982 54.397 1.000 54.380  ? 7    GLU BBB HB2  1 
ATOM   3463 H HB3  . GLU B 2 6   ? -5.323  -10.378 55.015 1.000 54.380  ? 7    GLU BBB HB3  1 
ATOM   3464 H HG2  . GLU B 2 6   ? -6.321  -11.813 53.728 1.000 55.420  ? 7    GLU BBB HG2  1 
ATOM   3465 H HG3  . GLU B 2 6   ? -6.100  -10.727 52.600 1.000 55.420  ? 7    GLU BBB HG3  1 
ATOM   3466 N N    . SER B 2 7   ? -4.250  -7.606  55.574 1.000 58.900  ? 8    SER BBB N    1 
ATOM   3467 C CA   . SER B 2 7   ? -3.680  -7.059  56.834 1.000 58.350  ? 8    SER BBB CA   1 
ATOM   3468 C C    . SER B 2 7   ? -4.719  -7.085  57.981 1.000 59.070  ? 8    SER BBB C    1 
ATOM   3469 O O    . SER B 2 7   ? -5.917  -7.304  57.685 1.000 57.720  ? 8    SER BBB O    1 
ATOM   3470 C CB   . SER B 2 7   ? -3.181  -5.677  56.575 1.000 52.780  ? 8    SER BBB CB   1 
ATOM   3471 O OG   . SER B 2 7   ? -4.268  -4.799  56.348 1.000 54.020  ? 8    SER BBB OG   1 
ATOM   3472 H H    . SER B 2 7   ? -5.210  -7.400  55.338 1.000 58.900  ? 8    SER BBB H    1 
ATOM   3473 H HA   . SER B 2 7   ? -2.919  -7.640  57.106 1.000 58.350  ? 8    SER BBB HA   1 
ATOM   3474 H HB2  . SER B 2 7   ? -2.661  -5.368  57.351 1.000 52.780  ? 8    SER BBB HB2  1 
ATOM   3475 H HB3  . SER B 2 7   ? -2.592  -5.686  55.787 1.000 52.780  ? 8    SER BBB HB3  1 
ATOM   3476 H HG   . SER B 2 7   ? -3.962  -4.024  56.204 0.000 54.020  ? 8    SER BBB HG   1 
ATOM   3477 N N    . GLY B 2 8   ? -4.274  -6.892  59.240 1.000 62.100  ? 9    GLY BBB N    1 
ATOM   3478 C CA   . GLY B 2 8   ? -5.109  -6.496  60.404 1.000 59.230  ? 9    GLY BBB CA   1 
ATOM   3479 C C    . GLY B 2 8   ? -5.380  -7.626  61.404 1.000 53.440  ? 9    GLY BBB C    1 
ATOM   3480 O O    . GLY B 2 8   ? -6.214  -7.413  62.339 1.000 56.670  ? 9    GLY BBB O    1 
ATOM   3481 H H    . GLY B 2 8   ? -3.283  -7.037  59.371 1.000 62.100  ? 9    GLY BBB H    1 
ATOM   3482 H HA2  . GLY B 2 8   ? -4.659  -5.759  60.889 1.000 59.230  ? 9    GLY BBB HA2  1 
ATOM   3483 H HA3  . GLY B 2 8   ? -5.981  -6.161  60.077 1.000 59.230  ? 9    GLY BBB HA3  1 
ATOM   3484 N N    . GLY B 2 9   ? -4.768  -8.797  61.196 1.000 53.050  ? 10   GLY BBB N    1 
ATOM   3485 C CA   . GLY B 2 9   ? -4.847  -9.978  62.086 1.000 55.830  ? 10   GLY BBB CA   1 
ATOM   3486 C C    . GLY B 2 9   ? -4.006  -9.790  63.349 1.000 58.720  ? 10   GLY BBB C    1 
ATOM   3487 O O    . GLY B 2 9   ? -3.296  -8.788  63.466 1.000 64.930  ? 10   GLY BBB O    1 
ATOM   3488 H H    . GLY B 2 9   ? -4.213  -8.851  60.354 1.000 53.050  ? 10   GLY BBB H    1 
ATOM   3489 H HA2  . GLY B 2 9   ? -5.792  -10.130 62.339 1.000 55.830  ? 10   GLY BBB HA2  1 
ATOM   3490 H HA3  . GLY B 2 9   ? -4.529  -10.776 61.594 1.000 55.830  ? 10   GLY BBB HA3  1 
ATOM   3491 N N    . GLY B 2 10  ? -4.099  -10.716 64.291 1.000 58.780  ? 11   GLY BBB N    1 
ATOM   3492 C CA   . GLY B 2 10  ? -3.490  -10.596 65.627 1.000 56.260  ? 11   GLY BBB CA   1 
ATOM   3493 C C    . GLY B 2 10  ? -4.221  -11.436 66.667 1.000 53.150  ? 11   GLY BBB C    1 
ATOM   3494 O O    . GLY B 2 10  ? -5.043  -12.329 66.321 1.000 50.630  ? 11   GLY BBB O    1 
ATOM   3495 H H    . GLY B 2 10  ? -4.623  -11.548 64.062 1.000 58.780  ? 11   GLY BBB H    1 
ATOM   3496 H HA2  . GLY B 2 10  ? -2.545  -10.887 65.579 1.000 56.260  ? 11   GLY BBB HA2  1 
ATOM   3497 H HA3  . GLY B 2 10  ? -3.506  -9.646  65.905 1.000 56.260  ? 11   GLY BBB HA3  1 
ATOM   3498 N N    . LEU B 2 11  ? -3.957  -11.147 67.929 1.000 60.170  ? 12   LEU BBB N    1 
ATOM   3499 C CA   . LEU B 2 11  ? -4.529  -11.898 69.073 1.000 61.610  ? 12   LEU BBB CA   1 
ATOM   3500 C C    . LEU B 2 11  ? -5.781  -11.147 69.565 1.000 57.970  ? 12   LEU BBB C    1 
ATOM   3501 O O    . LEU B 2 11  ? -5.766  -9.899  69.572 1.000 52.690  ? 12   LEU BBB O    1 
ATOM   3502 C CB   . LEU B 2 11  ? -3.407  -11.971 70.114 1.000 69.150  ? 12   LEU BBB CB   1 
ATOM   3503 C CG   . LEU B 2 11  ? -3.726  -12.678 71.431 1.000 77.980  ? 12   LEU BBB CG   1 
ATOM   3504 C CD1  . LEU B 2 11  ? -4.264  -14.085 71.198 1.000 78.590  ? 12   LEU BBB CD1  1 
ATOM   3505 C CD2  . LEU B 2 11  ? -2.494  -12.726 72.323 1.000 82.300  ? 12   LEU BBB CD2  1 
ATOM   3506 H H    . LEU B 2 11  ? -3.333  -10.374 68.110 1.000 60.170  ? 12   LEU BBB H    1 
ATOM   3507 H HA   . LEU B 2 11  ? -4.790  -12.795 68.759 1.000 61.610  ? 12   LEU BBB HA   1 
ATOM   3508 H HB2  . LEU B 2 11  ? -2.642  -12.428 69.710 1.000 69.150  ? 12   LEU BBB HB2  1 
ATOM   3509 H HB3  . LEU B 2 11  ? -3.126  -11.059 70.328 1.000 69.150  ? 12   LEU BBB HB3  1 
ATOM   3510 H HG   . LEU B 2 11  ? -4.425  -12.157 71.897 1.000 77.980  ? 12   LEU BBB HG   1 
ATOM   3511 H HD11 . LEU B 2 11  ? -5.080  -14.037 70.670 1.000 78.590  ? 12   LEU BBB HD11 1 
ATOM   3512 H HD12 . LEU B 2 11  ? -4.455  -14.505 72.054 1.000 78.590  ? 12   LEU BBB HD12 1 
ATOM   3513 H HD13 . LEU B 2 11  ? -3.600  -14.612 70.720 1.000 78.590  ? 12   LEU BBB HD13 1 
ATOM   3514 H HD21 . LEU B 2 11  ? -1.783  -13.210 71.868 1.000 82.300  ? 12   LEU BBB HD21 1 
ATOM   3515 H HD22 . LEU B 2 11  ? -2.714  -13.178 73.156 1.000 82.300  ? 12   LEU BBB HD22 1 
ATOM   3516 H HD23 . LEU B 2 11  ? -2.197  -11.820 72.515 1.000 82.300  ? 12   LEU BBB HD23 1 
ATOM   3517 N N    . VAL B 2 12  ? -6.868  -11.841 69.911 1.000 64.310  ? 13   VAL BBB N    1 
ATOM   3518 C CA   . VAL B 2 12  ? -8.026  -11.189 70.610 1.000 70.190  ? 13   VAL BBB CA   1 
ATOM   3519 C C    . VAL B 2 12  ? -8.566  -12.083 71.735 1.000 65.440  ? 13   VAL BBB C    1 
ATOM   3520 O O    . VAL B 2 12  ? -8.444  -13.329 71.633 1.000 62.930  ? 13   VAL BBB O    1 
ATOM   3521 C CB   . VAL B 2 12  ? -9.169  -10.797 69.650 1.000 72.550  ? 13   VAL BBB CB   1 
ATOM   3522 C CG1  . VAL B 2 12  ? -8.811  -9.578  68.817 1.000 80.410  ? 13   VAL BBB CG1  1 
ATOM   3523 C CG2  . VAL B 2 12  ? -9.602  -11.963 68.779 1.000 68.820  ? 13   VAL BBB CG2  1 
ATOM   3524 H H    . VAL B 2 12  ? -6.913  -12.827 69.698 1.000 64.310  ? 13   VAL BBB H    1 
ATOM   3525 H HA   . VAL B 2 12  ? -7.712  -10.362 71.019 1.000 70.190  ? 13   VAL BBB HA   1 
ATOM   3526 H HB   . VAL B 2 12  ? -9.944  -10.537 70.207 1.000 72.550  ? 13   VAL BBB HB   1 
ATOM   3527 H HG11 . VAL B 2 12  ? -8.633  -8.824  69.405 1.000 80.410  ? 13   VAL BBB HG11 1 
ATOM   3528 H HG12 . VAL B 2 12  ? -9.552  -9.360  68.225 1.000 80.410  ? 13   VAL BBB HG12 1 
ATOM   3529 H HG13 . VAL B 2 12  ? -8.018  -9.769  68.286 1.000 80.410  ? 13   VAL BBB HG13 1 
ATOM   3530 H HG21 . VAL B 2 12  ? -8.847  -12.268 68.246 1.000 68.820  ? 13   VAL BBB HG21 1 
ATOM   3531 H HG22 . VAL B 2 12  ? -10.322 -11.678 68.190 1.000 68.820  ? 13   VAL BBB HG22 1 
ATOM   3532 H HG23 . VAL B 2 12  ? -9.915  -12.691 69.343 1.000 68.820  ? 13   VAL BBB HG23 1 
ATOM   3533 N N    . GLN B 2 13  ? -9.194  -11.430 72.725 1.000 70.310  ? 14   GLN BBB N    1 
ATOM   3534 C CA   . GLN B 2 13  ? -10.012 -12.019 73.817 1.000 69.750  ? 14   GLN BBB CA   1 
ATOM   3535 C C    . GLN B 2 13  ? -11.224 -12.655 73.171 1.000 60.500  ? 14   GLN BBB C    1 
ATOM   3536 O O    . GLN B 2 13  ? -11.788 -12.062 72.252 1.000 59.680  ? 14   GLN BBB O    1 
ATOM   3537 C CB   . GLN B 2 13  ? -10.507 -10.934 74.783 1.000 80.530  ? 14   GLN BBB CB   1 
ATOM   3538 C CG   . GLN B 2 13  ? -9.393  -10.161 75.487 1.000 91.600  ? 14   GLN BBB CG   1 
ATOM   3539 C CD   . GLN B 2 13  ? -8.515  -11.054 76.337 1.000 99.950  ? 14   GLN BBB CD   1 
ATOM   3540 O OE1  . GLN B 2 13  ? -7.289  -10.935 76.348 1.000 94.200  ? 14   GLN BBB OE1  1 
ATOM   3541 N NE2  . GLN B 2 13  ? -9.137  -11.976 77.057 1.000 101.840 ? 14   GLN BBB NE2  1 
ATOM   3542 H H    . GLN B 2 13  ? -9.072  -10.428 72.687 1.000 70.310  ? 14   GLN BBB H    1 
ATOM   3543 H HA   . GLN B 2 13  ? -9.475  -12.708 74.272 1.000 69.750  ? 14   GLN BBB HA   1 
ATOM   3544 H HB2  . GLN B 2 13  ? -11.062 -10.300 74.282 1.000 80.530  ? 14   GLN BBB HB2  1 
ATOM   3545 H HB3  . GLN B 2 13  ? -11.074 -11.356 75.462 1.000 80.530  ? 14   GLN BBB HB3  1 
ATOM   3546 H HG2  . GLN B 2 13  ? -8.836  -9.714  74.815 1.000 91.600  ? 14   GLN BBB HG2  1 
ATOM   3547 H HG3  . GLN B 2 13  ? -9.791  -9.470  76.058 1.000 91.600  ? 14   GLN BBB HG3  1 
ATOM   3548 H HE21 . GLN B 2 13  ? -8.672  -12.524 77.571 0.000 101.840 ? 14   GLN BBB HE21 1 
ATOM   3549 H HE22 . GLN B 2 13  ? -10.018 -12.043 77.024 0.000 101.840 ? 14   GLN BBB HE22 1 
ATOM   3550 N N    . PRO B 2 14  ? -11.661 -13.851 73.625 1.000 61.640  ? 15   PRO BBB N    1 
ATOM   3551 C CA   . PRO B 2 14  ? -12.967 -14.403 73.239 1.000 64.450  ? 15   PRO BBB CA   1 
ATOM   3552 C C    . PRO B 2 14  ? -14.085 -13.384 73.479 1.000 65.790  ? 15   PRO BBB C    1 
ATOM   3553 O O    . PRO B 2 14  ? -13.955 -12.621 74.427 1.000 70.450  ? 15   PRO BBB O    1 
ATOM   3554 C CB   . PRO B 2 14  ? -13.132 -15.647 74.116 1.000 64.090  ? 15   PRO BBB CB   1 
ATOM   3555 C CG   . PRO B 2 14  ? -11.704 -16.073 74.376 1.000 66.790  ? 15   PRO BBB CG   1 
ATOM   3556 C CD   . PRO B 2 14  ? -10.901 -14.780 74.468 1.000 64.530  ? 15   PRO BBB CD   1 
ATOM   3557 H HA   . PRO B 2 14  ? -12.942 -14.666 72.285 1.000 64.450  ? 15   PRO BBB HA   1 
ATOM   3558 H HB2  . PRO B 2 14  ? -13.607 -15.432 74.946 1.000 64.090  ? 15   PRO BBB HB2  1 
ATOM   3559 H HB3  . PRO B 2 14  ? -13.642 -16.341 73.649 1.000 64.090  ? 15   PRO BBB HB3  1 
ATOM   3560 H HG2  . PRO B 2 14  ? -11.638 -16.583 75.210 1.000 66.790  ? 15   PRO BBB HG2  1 
ATOM   3561 H HG3  . PRO B 2 14  ? -11.370 -16.638 73.648 1.000 66.790  ? 15   PRO BBB HG3  1 
ATOM   3562 H HD2  . PRO B 2 14  ? -10.845 -14.469 75.396 1.000 64.530  ? 15   PRO BBB HD2  1 
ATOM   3563 H HD3  . PRO B 2 14  ? -9.988  -14.911 74.136 1.000 64.530  ? 15   PRO BBB HD3  1 
ATOM   3564 N N    . GLY B 2 15  ? -15.082 -13.347 72.578 1.000 66.550  ? 16   GLY BBB N    1 
ATOM   3565 C CA   . GLY B 2 15  ? -16.152 -12.326 72.514 1.000 57.270  ? 16   GLY BBB CA   1 
ATOM   3566 C C    . GLY B 2 15  ? -15.661 -10.989 71.964 1.000 56.710  ? 16   GLY BBB C    1 
ATOM   3567 O O    . GLY B 2 15  ? -16.513 -10.107 71.785 1.000 65.070  ? 16   GLY BBB O    1 
ATOM   3568 H H    . GLY B 2 15  ? -15.073 -14.094 71.899 1.000 66.550  ? 16   GLY BBB H    1 
ATOM   3569 H HA2  . GLY B 2 15  ? -16.884 -12.660 71.937 1.000 57.270  ? 16   GLY BBB HA2  1 
ATOM   3570 H HA3  . GLY B 2 15  ? -16.518 -12.184 73.423 1.000 57.270  ? 16   GLY BBB HA3  1 
ATOM   3571 N N    . GLY B 2 16  ? -14.350 -10.835 71.701 1.000 55.450  ? 17   GLY BBB N    1 
ATOM   3572 C CA   . GLY B 2 16  ? -13.745 -9.645  71.057 1.000 55.740  ? 17   GLY BBB CA   1 
ATOM   3573 C C    . GLY B 2 16  ? -14.103 -9.480  69.566 1.000 56.250  ? 17   GLY BBB C    1 
ATOM   3574 O O    . GLY B 2 16  ? -14.804 -10.342 68.962 1.000 51.250  ? 17   GLY BBB O    1 
ATOM   3575 H H    . GLY B 2 16  ? -13.754 -11.604 71.973 1.000 55.450  ? 17   GLY BBB H    1 
ATOM   3576 H HA2  . GLY B 2 16  ? -14.043 -8.832  71.537 1.000 55.740  ? 17   GLY BBB HA2  1 
ATOM   3577 H HA3  . GLY B 2 16  ? -12.760 -9.703  71.132 1.000 55.740  ? 17   GLY BBB HA3  1 
ATOM   3578 N N    . SER B 2 17  ? -13.614 -8.384  68.988 1.000 56.100  ? 18   SER BBB N    1 
ATOM   3579 C CA   . SER B 2 17  ? -13.960 -7.844  67.651 1.000 67.120  ? 18   SER BBB CA   1 
ATOM   3580 C C    . SER B 2 17  ? -12.676 -7.627  66.859 1.000 62.070  ? 18   SER BBB C    1 
ATOM   3581 O O    . SER B 2 17  ? -11.666 -7.296  67.491 1.000 63.980  ? 18   SER BBB O    1 
ATOM   3582 C CB   . SER B 2 17  ? -14.713 -6.547  67.779 1.000 63.510  ? 18   SER BBB CB   1 
ATOM   3583 O OG   . SER B 2 17  ? -16.103 -6.792  67.755 1.000 80.230  ? 18   SER BBB OG   1 
ATOM   3584 H H    . SER B 2 17  ? -12.936 -7.896  69.556 1.000 56.100  ? 18   SER BBB H    1 
ATOM   3585 H HA   . SER B 2 17  ? -14.515 -8.522  67.179 1.000 67.120  ? 18   SER BBB HA   1 
ATOM   3586 H HB2  . SER B 2 17  ? -14.466 -6.109  68.625 1.000 63.510  ? 18   SER BBB HB2  1 
ATOM   3587 H HB3  . SER B 2 17  ? -14.466 -5.952  67.035 1.000 63.510  ? 18   SER BBB HB3  1 
ATOM   3588 H HG   . SER B 2 17  ? -16.508 -6.053  67.828 0.000 80.230  ? 18   SER BBB HG   1 
ATOM   3589 N N    . LEU B 2 18  ? -12.732 -7.759  65.535 1.000 61.510  ? 19   LEU BBB N    1 
ATOM   3590 C CA   . LEU B 2 18  ? -11.545 -7.562  64.656 1.000 59.680  ? 19   LEU BBB CA   1 
ATOM   3591 C C    . LEU B 2 18  ? -11.961 -7.311  63.197 1.000 51.470  ? 19   LEU BBB C    1 
ATOM   3592 O O    . LEU B 2 18  ? -12.815 -8.052  62.649 1.000 47.590  ? 19   LEU BBB O    1 
ATOM   3593 C CB   . LEU B 2 18  ? -10.637 -8.791  64.794 1.000 53.920  ? 19   LEU BBB CB   1 
ATOM   3594 C CG   . LEU B 2 18  ? -9.189  -8.618  64.331 1.000 56.920  ? 19   LEU BBB CG   1 
ATOM   3595 C CD1  . LEU B 2 18  ? -8.466  -7.518  65.103 1.000 50.370  ? 19   LEU BBB CD1  1 
ATOM   3596 C CD2  . LEU B 2 18  ? -8.444  -9.940  64.454 1.000 60.070  ? 19   LEU BBB CD2  1 
ATOM   3597 H H    . LEU B 2 18  ? -13.619 -8.003  65.118 1.000 61.510  ? 19   LEU BBB H    1 
ATOM   3598 H HA   . LEU B 2 18  ? -11.053 -6.768  64.969 1.000 59.680  ? 19   LEU BBB HA   1 
ATOM   3599 H HB2  . LEU B 2 18  ? -10.624 -9.060  65.734 1.000 53.920  ? 19   LEU BBB HB2  1 
ATOM   3600 H HB3  . LEU B 2 18  ? -11.033 -9.525  64.283 1.000 53.920  ? 19   LEU BBB HB3  1 
ATOM   3601 H HG   . LEU B 2 18  ? -9.201  -8.352  63.379 1.000 56.920  ? 19   LEU BBB HG   1 
ATOM   3602 H HD11 . LEU B 2 18  ? -8.929  -6.672  64.973 1.000 50.370  ? 19   LEU BBB HD11 1 
ATOM   3603 H HD12 . LEU B 2 18  ? -7.552  -7.442  64.779 1.000 50.370  ? 19   LEU BBB HD12 1 
ATOM   3604 H HD13 . LEU B 2 18  ? -8.456  -7.739  66.051 1.000 50.370  ? 19   LEU BBB HD13 1 
ATOM   3605 H HD21 . LEU B 2 18  ? -8.452  -10.232 65.382 1.000 60.070  ? 19   LEU BBB HD21 1 
ATOM   3606 H HD22 . LEU B 2 18  ? -7.525  -9.823  64.157 1.000 60.070  ? 19   LEU BBB HD22 1 
ATOM   3607 H HD23 . LEU B 2 18  ? -8.880  -10.611 63.900 1.000 60.070  ? 19   LEU BBB HD23 1 
ATOM   3608 N N    . ARG B 2 19  ? -11.337 -6.312  62.588 1.000 48.630  ? 20   ARG BBB N    1 
ATOM   3609 C CA   . ARG B 2 19  ? -11.528 -5.979  61.163 1.000 50.500  ? 20   ARG BBB CA   1 
ATOM   3610 C C    . ARG B 2 19  ? -10.315 -6.435  60.358 1.000 51.030  ? 20   ARG BBB C    1 
ATOM   3611 O O    . ARG B 2 19  ? -9.191  -5.909  60.616 1.000 47.440  ? 20   ARG BBB O    1 
ATOM   3612 C CB   . ARG B 2 19  ? -11.684 -4.474  61.009 1.000 51.710  ? 20   ARG BBB CB   1 
ATOM   3613 C CG   . ARG B 2 19  ? -12.112 -4.086  59.602 1.000 59.830  ? 20   ARG BBB CG   1 
ATOM   3614 C CD   . ARG B 2 19  ? -13.236 -3.110  59.754 1.000 57.910  ? 20   ARG BBB CD   1 
ATOM   3615 N NE   . ARG B 2 19  ? -13.537 -2.444  58.528 1.000 61.040  ? 20   ARG BBB NE   1 
ATOM   3616 C CZ   . ARG B 2 19  ? -12.754 -1.540  57.970 1.000 65.560  ? 20   ARG BBB CZ   1 
ATOM   3617 N NH1  . ARG B 2 19  ? -11.567 -1.253  58.476 1.000 60.130  ? 20   ARG BBB NH1  1 
ATOM   3618 N NH2  . ARG B 2 19  ? -13.144 -0.958  56.858 1.000 76.540  ? 20   ARG BBB NH2  1 
ATOM   3619 H H    . ARG B 2 19  ? -10.700 -5.758  63.142 1.000 48.630  ? 20   ARG BBB H    1 
ATOM   3620 H HA   . ARG B 2 19  ? -12.322 -6.460  60.833 1.000 50.500  ? 20   ARG BBB HA   1 
ATOM   3621 H HB2  . ARG B 2 19  ? -12.349 -4.162  61.657 1.000 51.710  ? 20   ARG BBB HB2  1 
ATOM   3622 H HB3  . ARG B 2 19  ? -10.828 -4.048  61.226 1.000 51.710  ? 20   ARG BBB HB3  1 
ATOM   3623 H HG2  . ARG B 2 19  ? -11.348 -3.694  59.128 1.000 59.830  ? 20   ARG BBB HG2  1 
ATOM   3624 H HG3  . ARG B 2 19  ? -12.389 -4.891  59.114 1.000 59.830  ? 20   ARG BBB HG3  1 
ATOM   3625 H HD2  . ARG B 2 19  ? -14.034 -3.584  60.071 1.000 57.910  ? 20   ARG BBB HD2  1 
ATOM   3626 H HD3  . ARG B 2 19  ? -12.996 -2.445  60.435 1.000 57.910  ? 20   ARG BBB HD3  1 
ATOM   3627 H HE   . ARG B 2 19  ? -14.283 -2.648  58.126 1.000 61.040  ? 20   ARG BBB HE   1 
ATOM   3628 H HH11 . ARG B 2 19  ? -11.287 -1.669  59.198 1.000 60.130  ? 20   ARG BBB HH11 1 
ATOM   3629 H HH12 . ARG B 2 19  ? -11.061 -0.647  58.089 1.000 60.130  ? 20   ARG BBB HH12 1 
ATOM   3630 H HH21 . ARG B 2 19  ? -13.918 -1.175  56.498 1.000 76.540  ? 20   ARG BBB HH21 1 
ATOM   3631 H HH22 . ARG B 2 19  ? -12.630 -0.353  56.476 1.000 76.540  ? 20   ARG BBB HH22 1 
ATOM   3632 N N    . LEU B 2 20  ? -10.532 -7.334  59.389 1.000 48.830  ? 21   LEU BBB N    1 
ATOM   3633 C CA   . LEU B 2 20  ? -9.511  -7.667  58.353 1.000 46.670  ? 21   LEU BBB CA   1 
ATOM   3634 C C    . LEU B 2 20  ? -9.711  -6.795  57.094 1.000 51.470  ? 21   LEU BBB C    1 
ATOM   3635 O O    . LEU B 2 20  ? -10.886 -6.570  56.684 1.000 51.500  ? 21   LEU BBB O    1 
ATOM   3636 C CB   . LEU B 2 20  ? -9.607  -9.158  58.033 1.000 45.050  ? 21   LEU BBB CB   1 
ATOM   3637 C CG   . LEU B 2 20  ? -9.310  -10.118 59.188 1.000 50.280  ? 21   LEU BBB CG   1 
ATOM   3638 C CD1  . LEU B 2 20  ? -9.251  -11.550 58.693 1.000 52.380  ? 21   LEU BBB CD1  1 
ATOM   3639 C CD2  . LEU B 2 20  ? -8.012  -9.783  59.926 1.000 52.650  ? 21   LEU BBB CD2  1 
ATOM   3640 H H    . LEU B 2 20  ? -11.427 -7.801  59.366 1.000 48.830  ? 21   LEU BBB H    1 
ATOM   3641 H HA   . LEU B 2 20  ? -8.618  -7.475  58.721 1.000 46.670  ? 21   LEU BBB HA   1 
ATOM   3642 H HB2  . LEU B 2 20  ? -10.510 -9.345  57.707 1.000 45.050  ? 21   LEU BBB HB2  1 
ATOM   3643 H HB3  . LEU B 2 20  ? -8.985  -9.357  57.305 1.000 45.050  ? 21   LEU BBB HB3  1 
ATOM   3644 H HG   . LEU B 2 20  ? -10.045 -10.043 59.846 1.000 50.280  ? 21   LEU BBB HG   1 
ATOM   3645 H HD11 . LEU B 2 20  ? -10.105 -11.791 58.295 1.000 52.380  ? 21   LEU BBB HD11 1 
ATOM   3646 H HD12 . LEU B 2 20  ? -9.061  -12.144 59.440 1.000 52.380  ? 21   LEU BBB HD12 1 
ATOM   3647 H HD13 . LEU B 2 20  ? -8.548  -11.634 58.026 1.000 52.380  ? 21   LEU BBB HD13 1 
ATOM   3648 H HD21 . LEU B 2 20  ? -7.265  -9.828  59.305 1.000 52.650  ? 21   LEU BBB HD21 1 
ATOM   3649 H HD22 . LEU B 2 20  ? -7.874  -10.422 60.647 1.000 52.650  ? 21   LEU BBB HD22 1 
ATOM   3650 H HD23 . LEU B 2 20  ? -8.072  -8.885  60.296 1.000 52.650  ? 21   LEU BBB HD23 1 
ATOM   3651 N N    . SER B 2 21  ? -8.600  -6.319  56.516 1.000 46.160  ? 22   SER BBB N    1 
ATOM   3652 C CA   . SER B 2 21  ? -8.516  -5.553  55.245 1.000 47.710  ? 22   SER BBB CA   1 
ATOM   3653 C C    . SER B 2 21  ? -7.800  -6.390  54.172 1.000 51.740  ? 22   SER BBB C    1 
ATOM   3654 O O    . SER B 2 21  ? -6.946  -7.222  54.547 1.000 59.050  ? 22   SER BBB O    1 
ATOM   3655 C CB   . SER B 2 21  ? -7.810  -4.256  55.482 1.000 45.890  ? 22   SER BBB CB   1 
ATOM   3656 O OG   . SER B 2 21  ? -8.555  -3.460  56.394 1.000 46.390  ? 22   SER BBB OG   1 
ATOM   3657 H H    . SER B 2 21  ? -7.752  -6.521  57.026 1.000 46.160  ? 22   SER BBB H    1 
ATOM   3658 H HA   . SER B 2 21  ? -9.443  -5.374  54.931 1.000 47.710  ? 22   SER BBB HA   1 
ATOM   3659 H HB2  . SER B 2 21  ? -6.914  -4.435  55.848 1.000 45.890  ? 22   SER BBB HB2  1 
ATOM   3660 H HB3  . SER B 2 21  ? -7.709  -3.780  54.627 1.000 45.890  ? 22   SER BBB HB3  1 
ATOM   3661 H HG   . SER B 2 21  ? -8.141  -2.732  56.516 0.000 46.390  ? 22   SER BBB HG   1 
ATOM   3662 N N    . CYS B 2 22  ? -8.158  -6.215  52.895 1.000 47.000  ? 23   CYS BBB N    1 
ATOM   3663 C CA   . CYS B 2 22  ? -7.491  -6.834  51.715 1.000 44.770  ? 23   CYS BBB CA   1 
ATOM   3664 C C    . CYS B 2 22  ? -7.368  -5.780  50.618 1.000 44.940  ? 23   CYS BBB C    1 
ATOM   3665 O O    . CYS B 2 22  ? -8.411  -5.202  50.211 1.000 44.570  ? 23   CYS BBB O    1 
ATOM   3666 C CB   . CYS B 2 22  ? -8.278  -8.021  51.182 1.000 51.290  ? 23   CYS BBB CB   1 
ATOM   3667 S SG   . CYS B 2 22  ? -7.536  -8.891  49.758 1.000 51.050  ? 23   CYS BBB SG   1 
ATOM   3668 H H    . CYS B 2 22  ? -8.951  -5.607  52.749 1.000 47.000  ? 23   CYS BBB H    1 
ATOM   3669 H HA   . CYS B 2 22  ? -6.589  -7.118  51.990 1.000 44.770  ? 23   CYS BBB HA   1 
ATOM   3670 H HB2  . CYS B 2 22  ? -8.391  -8.678  51.899 1.000 51.290  ? 23   CYS BBB HB2  1 
ATOM   3671 H HB3  . CYS B 2 22  ? -9.168  -7.719  50.907 1.000 51.290  ? 23   CYS BBB HB3  1 
ATOM   3672 N N    . ALA B 2 23  ? -6.140  -5.493  50.217 1.000 40.380  ? 24   ALA BBB N    1 
ATOM   3673 C CA   . ALA B 2 23  ? -5.821  -4.487  49.186 1.000 43.970  ? 24   ALA BBB CA   1 
ATOM   3674 C C    . ALA B 2 23  ? -5.601  -5.242  47.884 1.000 43.560  ? 24   ALA BBB C    1 
ATOM   3675 O O    . ALA B 2 23  ? -4.714  -6.130  47.889 1.000 45.170  ? 24   ALA BBB O    1 
ATOM   3676 C CB   . ALA B 2 23  ? -4.620  -3.663  49.592 1.000 44.420  ? 24   ALA BBB CB   1 
ATOM   3677 H H    . ALA B 2 23  ? -5.388  -6.005  50.655 1.000 40.380  ? 24   ALA BBB H    1 
ATOM   3678 H HA   . ALA B 2 23  ? -6.591  -3.878  49.093 1.000 43.970  ? 24   ALA BBB HA   1 
ATOM   3679 H HB1  . ALA B 2 23  ? -4.427  -3.009  48.902 1.000 44.420  ? 24   ALA BBB HB1  1 
ATOM   3680 H HB2  . ALA B 2 23  ? -4.807  -3.205  50.426 1.000 44.420  ? 24   ALA BBB HB2  1 
ATOM   3681 H HB3  . ALA B 2 23  ? -3.851  -4.245  49.709 1.000 44.420  ? 24   ALA BBB HB3  1 
ATOM   3682 N N    . ALA B 2 24  ? -6.451  -4.980  46.876 1.000 45.040  ? 25   ALA BBB N    1 
ATOM   3683 C CA   . ALA B 2 24  ? -6.458  -5.673  45.571 1.000 46.240  ? 25   ALA BBB CA   1 
ATOM   3684 C C    . ALA B 2 24  ? -5.759  -4.756  44.578 1.000 51.030  ? 25   ALA BBB C    1 
ATOM   3685 O O    . ALA B 2 24  ? -6.052  -3.522  44.582 1.000 49.370  ? 25   ALA BBB O    1 
ATOM   3686 C CB   . ALA B 2 24  ? -7.864  -5.971  45.124 1.000 48.480  ? 25   ALA BBB CB   1 
ATOM   3687 H H    . ALA B 2 24  ? -7.127  -4.249  47.049 1.000 45.040  ? 25   ALA BBB H    1 
ATOM   3688 H HA   . ALA B 2 24  ? -5.953  -6.515  45.661 1.000 46.240  ? 25   ALA BBB HA   1 
ATOM   3689 H HB1  . ALA B 2 24  ? -7.843  -6.425  44.267 1.000 48.480  ? 25   ALA BBB HB1  1 
ATOM   3690 H HB2  . ALA B 2 24  ? -8.299  -6.539  45.779 1.000 48.480  ? 25   ALA BBB HB2  1 
ATOM   3691 H HB3  . ALA B 2 24  ? -8.361  -5.140  45.037 1.000 48.480  ? 25   ALA BBB HB3  1 
ATOM   3692 N N    . SER B 2 25  ? -4.874  -5.310  43.758 1.000 54.440  ? 26   SER BBB N    1 
ATOM   3693 C CA   . SER B 2 25  ? -4.131  -4.520  42.734 1.000 61.330  ? 26   SER BBB CA   1 
ATOM   3694 C C    . SER B 2 25  ? -3.927  -5.322  41.435 1.000 55.710  ? 26   SER BBB C    1 
ATOM   3695 O O    . SER B 2 25  ? -4.248  -6.543  41.406 1.000 53.850  ? 26   SER BBB O    1 
ATOM   3696 C CB   . SER B 2 25  ? -2.818  -4.047  43.304 1.000 57.000  ? 26   SER BBB CB   1 
ATOM   3697 O OG   . SER B 2 25  ? -1.929  -5.151  43.406 1.000 63.390  ? 26   SER BBB OG   1 
ATOM   3698 H H    . SER B 2 25  ? -4.702  -6.302  43.835 1.000 54.440  ? 26   SER BBB H    1 
ATOM   3699 H HA   . SER B 2 25  ? -4.676  -3.719  42.507 1.000 61.330  ? 26   SER BBB HA   1 
ATOM   3700 H HB2  . SER B 2 25  ? -2.438  -3.357  42.715 1.000 57.000  ? 26   SER BBB HB2  1 
ATOM   3701 H HB3  . SER B 2 25  ? -2.972  -3.651  44.191 1.000 57.000  ? 26   SER BBB HB3  1 
ATOM   3702 H HG   . SER B 2 25  ? -1.196  -4.877  43.726 0.000 63.390  ? 26   SER BBB HG   1 
ATOM   3703 N N    . GLY B 2 26  ? -3.400  -4.660  40.393 1.000 60.710  ? 27   GLY BBB N    1 
ATOM   3704 C CA   . GLY B 2 26  ? -3.070  -5.287  39.093 1.000 65.630  ? 27   GLY BBB CA   1 
ATOM   3705 C C    . GLY B 2 26  ? -4.038  -4.888  37.985 1.000 64.950  ? 27   GLY BBB C    1 
ATOM   3706 O O    . GLY B 2 26  ? -5.181  -4.466  38.311 1.000 53.810  ? 27   GLY BBB O    1 
ATOM   3707 H H    . GLY B 2 26  ? -3.225  -3.674  40.523 1.000 60.710  ? 27   GLY BBB H    1 
ATOM   3708 H HA2  . GLY B 2 26  ? -2.153  -5.021  38.830 1.000 65.630  ? 27   GLY BBB HA2  1 
ATOM   3709 H HA3  . GLY B 2 26  ? -3.087  -6.272  39.195 1.000 65.630  ? 27   GLY BBB HA3  1 
ATOM   3710 N N    . ARG B 2 27  ? -3.614  -5.074  36.730 1.000 68.910  ? 28   ARG BBB N    1 
ATOM   3711 C CA   . ARG B 2 27  ? -4.238  -4.471  35.519 1.000 77.320  ? 28   ARG BBB CA   1 
ATOM   3712 C C    . ARG B 2 27  ? -5.579  -5.173  35.351 1.000 66.830  ? 28   ARG BBB C    1 
ATOM   3713 O O    . ARG B 2 27  ? -6.591  -4.469  35.220 1.000 67.400  ? 28   ARG BBB O    1 
ATOM   3714 C CB   . ARG B 2 27  ? -3.421  -4.636  34.223 1.000 93.270  ? 28   ARG BBB CB   1 
ATOM   3715 C CG   . ARG B 2 27  ? -1.962  -5.048  34.383 1.000 105.810 ? 28   ARG BBB CG   1 
ATOM   3716 C CD   . ARG B 2 27  ? -1.128  -4.116  35.256 1.000 112.780 ? 28   ARG BBB CD   1 
ATOM   3717 N NE   . ARG B 2 27  ? 0.212   -4.643  35.504 1.000 121.010 ? 28   ARG BBB NE   1 
ATOM   3718 C CZ   . ARG B 2 27  ? 0.525   -5.653  36.326 1.000 107.360 ? 28   ARG BBB CZ   1 
ATOM   3719 N NH1  . ARG B 2 27  ? -0.403  -6.295  37.015 1.000 97.600  ? 28   ARG BBB NH1  1 
ATOM   3720 N NH2  . ARG B 2 27  ? 1.785   -6.030  36.450 1.000 100.100 ? 28   ARG BBB NH2  1 
ATOM   3721 H H    . ARG B 2 27  ? -2.808  -5.673  36.622 1.000 68.910  ? 28   ARG BBB H    1 
ATOM   3722 H HA   . ARG B 2 27  ? -4.372  -3.509  35.683 1.000 77.320  ? 28   ARG BBB HA   1 
ATOM   3723 H HB2  . ARG B 2 27  ? -3.858  -5.312  33.663 1.000 93.270  ? 28   ARG BBB HB2  1 
ATOM   3724 H HB3  . ARG B 2 27  ? -3.435  -3.786  33.735 1.000 93.270  ? 28   ARG BBB HB3  1 
ATOM   3725 H HG2  . ARG B 2 27  ? -1.920  -5.945  34.779 1.000 105.810 ? 28   ARG BBB HG2  1 
ATOM   3726 H HG3  . ARG B 2 27  ? -1.538  -5.088  33.499 1.000 105.810 ? 28   ARG BBB HG3  1 
ATOM   3727 H HD2  . ARG B 2 27  ? -1.056  -3.242  34.817 1.000 112.780 ? 28   ARG BBB HD2  1 
ATOM   3728 H HD3  . ARG B 2 27  ? -1.586  -3.981  36.113 1.000 112.780 ? 28   ARG BBB HD3  1 
ATOM   3729 H HE   . ARG B 2 27  ? 0.880   -4.273  35.083 1.000 121.010 ? 28   ARG BBB HE   1 
ATOM   3730 H HH11 . ARG B 2 27  ? -1.246  -6.060  36.938 1.000 97.600  ? 28   ARG BBB HH11 1 
ATOM   3731 H HH12 . ARG B 2 27  ? -0.174  -6.955  37.548 1.000 97.600  ? 28   ARG BBB HH12 1 
ATOM   3732 H HH21 . ARG B 2 27  ? 2.414   -5.616  35.992 1.000 100.100 ? 28   ARG BBB HH21 1 
ATOM   3733 H HH22 . ARG B 2 27  ? 1.993   -6.694  36.990 1.000 100.100 ? 28   ARG BBB HH22 1 
ATOM   3734 N N    . THR B 2 28  ? -5.575  -6.507  35.470 1.000 52.920  ? 29   THR BBB N    1 
ATOM   3735 C CA   . THR B 2 28  ? -6.745  -7.358  35.165 1.000 51.140  ? 29   THR BBB CA   1 
ATOM   3736 C C    . THR B 2 28  ? -7.773  -7.285  36.303 1.000 51.470  ? 29   THR BBB C    1 
ATOM   3737 O O    . THR B 2 28  ? -8.890  -7.815  36.137 1.000 61.040  ? 29   THR BBB O    1 
ATOM   3738 C CB   . THR B 2 28  ? -6.292  -8.767  34.776 1.000 53.580  ? 29   THR BBB CB   1 
ATOM   3739 O OG1  . THR B 2 28  ? -5.794  -9.399  35.945 1.000 58.340  ? 29   THR BBB OG1  1 
ATOM   3740 C CG2  . THR B 2 28  ? -5.242  -8.763  33.677 1.000 59.390  ? 29   THR BBB CG2  1 
ATOM   3741 H H    . THR B 2 28  ? -4.720  -6.941  35.786 1.000 52.920  ? 29   THR BBB H    1 
ATOM   3742 H HA   . THR B 2 28  ? -7.169  -7.011  34.346 1.000 51.140  ? 29   THR BBB HA   1 
ATOM   3743 H HB   . THR B 2 28  ? -7.081  -9.270  34.463 1.000 53.580  ? 29   THR BBB HB   1 
ATOM   3744 H HG1  . THR B 2 28  ? -5.535  -10.184 35.756 0.000 58.340  ? 29   THR BBB HG1  1 
ATOM   3745 H HG21 . THR B 2 28  ? -5.606  -8.338  32.880 1.000 59.390  ? 29   THR BBB HG21 1 
ATOM   3746 H HG22 . THR B 2 28  ? -4.988  -9.679  33.465 1.000 59.390  ? 29   THR BBB HG22 1 
ATOM   3747 H HG23 . THR B 2 28  ? -4.457  -8.271  33.977 1.000 59.390  ? 29   THR BBB HG23 1 
ATOM   3748 N N    . PHE B 2 29  ? -7.479  -6.614  37.410 1.000 50.330  ? 30   PHE BBB N    1 
ATOM   3749 C CA   . PHE B 2 29  ? -8.460  -6.515  38.517 1.000 47.320  ? 30   PHE BBB CA   1 
ATOM   3750 C C    . PHE B 2 29  ? -9.650  -5.703  38.014 1.000 46.000  ? 30   PHE BBB C    1 
ATOM   3751 O O    . PHE B 2 29  ? -9.382  -4.602  37.501 1.000 53.090  ? 30   PHE BBB O    1 
ATOM   3752 C CB   . PHE B 2 29  ? -7.853  -5.878  39.767 1.000 48.950  ? 30   PHE BBB CB   1 
ATOM   3753 C CG   . PHE B 2 29  ? -8.859  -5.729  40.881 1.000 45.840  ? 30   PHE BBB CG   1 
ATOM   3754 C CD1  . PHE B 2 29  ? -9.358  -6.853  41.522 1.000 46.350  ? 30   PHE BBB CD1  1 
ATOM   3755 C CD2  . PHE B 2 29  ? -9.346  -4.480  41.235 1.000 43.290  ? 30   PHE BBB CD2  1 
ATOM   3756 C CE1  . PHE B 2 29  ? -10.295 -6.718  42.537 1.000 50.080  ? 30   PHE BBB CE1  1 
ATOM   3757 C CE2  . PHE B 2 29  ? -10.287 -4.348  42.237 1.000 45.580  ? 30   PHE BBB CE2  1 
ATOM   3758 C CZ   . PHE B 2 29  ? -10.767 -5.470  42.878 1.000 51.390  ? 30   PHE BBB CZ   1 
ATOM   3759 H H    . PHE B 2 29  ? -6.580  -6.164  37.507 1.000 50.330  ? 30   PHE BBB H    1 
ATOM   3760 H HA   . PHE B 2 29  ? -8.764  -7.428  38.752 1.000 47.320  ? 30   PHE BBB HA   1 
ATOM   3761 H HB2  . PHE B 2 29  ? -7.101  -6.433  40.064 1.000 48.950  ? 30   PHE BBB HB2  1 
ATOM   3762 H HB3  . PHE B 2 29  ? -7.489  -5.002  39.523 1.000 48.950  ? 30   PHE BBB HB3  1 
ATOM   3763 H HD1  . PHE B 2 29  ? -9.064  -7.710  41.257 1.000 46.350  ? 30   PHE BBB HD1  1 
ATOM   3764 H HD2  . PHE B 2 29  ? -9.030  -3.713  40.785 1.000 43.290  ? 30   PHE BBB HD2  1 
ATOM   3765 H HE1  . PHE B 2 29  ? -10.631 -7.486  42.970 1.000 50.080  ? 30   PHE BBB HE1  1 
ATOM   3766 H HE2  . PHE B 2 29  ? -10.614 -3.495  42.474 1.000 45.580  ? 30   PHE BBB HE2  1 
ATOM   3767 H HZ   . PHE B 2 29  ? -11.404 -5.379  43.568 1.000 51.390  ? 30   PHE BBB HZ   1 
ATOM   3768 N N    . SER B 2 30  ? -10.878 -6.224  38.158 1.000 41.130  ? 31   SER BBB N    1 
ATOM   3769 C CA   . SER B 2 30  ? -12.134 -5.635  37.605 1.000 43.120  ? 31   SER BBB CA   1 
ATOM   3770 C C    . SER B 2 30  ? -13.233 -5.603  38.674 1.000 41.460  ? 31   SER BBB C    1 
ATOM   3771 O O    . SER B 2 30  ? -14.415 -5.881  38.353 1.000 38.100  ? 31   SER BBB O    1 
ATOM   3772 C CB   . SER B 2 30  ? -12.589 -6.395  36.383 1.000 41.130  ? 31   SER BBB CB   1 
ATOM   3773 O OG   . SER B 2 30  ? -12.991 -7.698  36.734 1.000 41.200  ? 31   SER BBB OG   1 
ATOM   3774 H H    . SER B 2 30  ? -10.928 -7.083  38.687 1.000 41.130  ? 31   SER BBB H    1 
ATOM   3775 H HA   . SER B 2 30  ? -11.942 -4.696  37.336 1.000 43.120  ? 31   SER BBB HA   1 
ATOM   3776 H HB2  . SER B 2 30  ? -13.342 -5.919  35.965 1.000 41.130  ? 31   SER BBB HB2  1 
ATOM   3777 H HB3  . SER B 2 30  ? -11.850 -6.441  35.735 1.000 41.130  ? 31   SER BBB HB3  1 
ATOM   3778 H HG   . SER B 2 30  ? -13.240 -8.100  36.033 0.000 41.200  ? 31   SER BBB HG   1 
ATOM   3779 N N    . TYR B 2 31  ? -12.844 -5.361  39.927 1.000 45.170  ? 32   TYR BBB N    1 
ATOM   3780 C CA   . TYR B 2 31  ? -13.749 -5.409  41.109 1.000 37.910  ? 32   TYR BBB CA   1 
ATOM   3781 C C    . TYR B 2 31  ? -14.455 -6.766  41.150 1.000 33.250  ? 32   TYR BBB C    1 
ATOM   3782 O O    . TYR B 2 31  ? -15.683 -6.807  41.292 1.000 38.460  ? 32   TYR BBB O    1 
ATOM   3783 C CB   . TYR B 2 31  ? -14.710 -4.221  41.002 1.000 41.190  ? 32   TYR BBB CB   1 
ATOM   3784 C CG   . TYR B 2 31  ? -14.016 -2.930  40.659 1.000 43.080  ? 32   TYR BBB CG   1 
ATOM   3785 C CD1  . TYR B 2 31  ? -13.404 -2.175  41.635 1.000 47.100  ? 32   TYR BBB CD1  1 
ATOM   3786 C CD2  . TYR B 2 31  ? -13.932 -2.486  39.349 1.000 49.550  ? 32   TYR BBB CD2  1 
ATOM   3787 C CE1  . TYR B 2 31  ? -12.751 -0.993  41.334 1.000 53.090  ? 32   TYR BBB CE1  1 
ATOM   3788 C CE2  . TYR B 2 31  ? -13.308 -1.292  39.030 1.000 49.020  ? 32   TYR BBB CE2  1 
ATOM   3789 C CZ   . TYR B 2 31  ? -12.719 -0.538  40.030 1.000 55.610  ? 32   TYR BBB CZ   1 
ATOM   3790 O OH   . TYR B 2 31  ? -12.111 0.649   39.751 1.000 50.740  ? 32   TYR BBB OH   1 
ATOM   3791 H H    . TYR B 2 31  ? -11.870 -5.132  40.062 1.000 45.170  ? 32   TYR BBB H    1 
ATOM   3792 H HA   . TYR B 2 31  ? -13.202 -5.314  41.930 1.000 37.910  ? 32   TYR BBB HA   1 
ATOM   3793 H HB2  . TYR B 2 31  ? -15.382 -4.427  40.319 1.000 41.190  ? 32   TYR BBB HB2  1 
ATOM   3794 H HB3  . TYR B 2 31  ? -15.182 -4.126  41.856 1.000 41.190  ? 32   TYR BBB HB3  1 
ATOM   3795 H HD1  . TYR B 2 31  ? -13.422 -2.474  42.529 1.000 47.100  ? 32   TYR BBB HD1  1 
ATOM   3796 H HD2  . TYR B 2 31  ? -14.308 -3.008  38.659 1.000 49.550  ? 32   TYR BBB HD2  1 
ATOM   3797 H HE1  . TYR B 2 31  ? -12.339 -0.492  42.018 1.000 53.090  ? 32   TYR BBB HE1  1 
ATOM   3798 H HE2  . TYR B 2 31  ? -13.290 -0.988  38.138 1.000 49.020  ? 32   TYR BBB HE2  1 
ATOM   3799 H HH   . TYR B 2 31  ? -11.285 0.617   39.979 0.000 50.740  ? 32   TYR BBB HH   1 
ATOM   3800 N N    . ASN B 2 32  ? -13.702 -7.855  40.987 1.000 30.900  ? 33   ASN BBB N    1 
ATOM   3801 C CA   . ASN B 2 32  ? -14.241 -9.241  40.930 1.000 33.550  ? 33   ASN BBB CA   1 
ATOM   3802 C C    . ASN B 2 32  ? -15.059 -9.593  42.174 1.000 36.440  ? 33   ASN BBB C    1 
ATOM   3803 O O    . ASN B 2 32  ? -14.817 -9.051  43.253 1.000 38.590  ? 33   ASN BBB O    1 
ATOM   3804 C CB   . ASN B 2 32  ? -13.119 -10.263 40.889 1.000 36.990  ? 33   ASN BBB CB   1 
ATOM   3805 C CG   . ASN B 2 32  ? -12.119 -10.005 39.787 1.000 37.830  ? 33   ASN BBB CG   1 
ATOM   3806 O OD1  . ASN B 2 32  ? -11.523 -8.919  39.726 1.000 35.930  ? 33   ASN BBB OD1  1 
ATOM   3807 N ND2  . ASN B 2 32  ? -11.930 -11.014 38.952 1.000 33.920  ? 33   ASN BBB ND2  1 
ATOM   3808 H H    . ASN B 2 32  ? -12.706 -7.710  40.899 1.000 30.900  ? 33   ASN BBB H    1 
ATOM   3809 H HA   . ASN B 2 32  ? -14.842 -9.311  40.152 1.000 33.550  ? 33   ASN BBB HA   1 
ATOM   3810 H HB2  . ASN B 2 32  ? -12.653 -10.257 41.750 1.000 36.990  ? 33   ASN BBB HB2  1 
ATOM   3811 H HB3  . ASN B 2 32  ? -13.506 -11.154 40.765 1.000 36.990  ? 33   ASN BBB HB3  1 
ATOM   3812 H HD21 . ASN B 2 32  ? -11.358 -10.933 38.283 0.000 33.920  ? 33   ASN BBB HD21 1 
ATOM   3813 H HD22 . ASN B 2 32  ? -12.375 -11.769 39.063 0.000 33.920  ? 33   ASN BBB HD22 1 
ATOM   3814 N N    . PRO B 2 33  ? -15.994 -10.563 42.115 1.000 34.260  ? 34   PRO BBB N    1 
ATOM   3815 C CA   . PRO B 2 33  ? -16.567 -11.104 43.338 1.000 38.870  ? 34   PRO BBB CA   1 
ATOM   3816 C C    . PRO B 2 33  ? -15.395 -11.571 44.234 1.000 44.710  ? 34   PRO BBB C    1 
ATOM   3817 O O    . PRO B 2 33  ? -14.412 -12.130 43.724 1.000 44.580  ? 34   PRO BBB O    1 
ATOM   3818 C CB   . PRO B 2 33  ? -17.477 -12.247 42.843 1.000 37.870  ? 34   PRO BBB CB   1 
ATOM   3819 C CG   . PRO B 2 33  ? -17.704 -11.943 41.375 1.000 38.390  ? 34   PRO BBB CG   1 
ATOM   3820 C CD   . PRO B 2 33  ? -16.442 -11.271 40.911 1.000 36.740  ? 34   PRO BBB CD   1 
ATOM   3821 H HA   . PRO B 2 33  ? -17.116 -10.408 43.778 1.000 38.870  ? 34   PRO BBB HA   1 
ATOM   3822 H HB2  . PRO B 2 33  ? -17.044 -13.118 42.962 1.000 37.870  ? 34   PRO BBB HB2  1 
ATOM   3823 H HB3  . PRO B 2 33  ? -18.323 -12.262 43.337 1.000 37.870  ? 34   PRO BBB HB3  1 
ATOM   3824 H HG2  . PRO B 2 33  ? -17.868 -12.766 40.870 1.000 38.390  ? 34   PRO BBB HG2  1 
ATOM   3825 H HG3  . PRO B 2 33  ? -18.478 -11.354 41.256 1.000 38.390  ? 34   PRO BBB HG3  1 
ATOM   3826 H HD2  . PRO B 2 33  ? -15.787 -11.932 40.605 1.000 36.740  ? 34   PRO BBB HD2  1 
ATOM   3827 H HD3  . PRO B 2 33  ? -16.625 -10.659 40.168 1.000 36.740  ? 34   PRO BBB HD3  1 
ATOM   3828 N N    . MET B 2 34  ? -15.475 -11.293 45.537 1.000 41.540  ? 35   MET BBB N    1 
ATOM   3829 C CA   . MET B 2 34  ? -14.421 -11.642 46.512 1.000 42.920  ? 35   MET BBB CA   1 
ATOM   3830 C C    . MET B 2 34  ? -15.021 -12.548 47.581 1.000 44.310  ? 35   MET BBB C    1 
ATOM   3831 O O    . MET B 2 34  ? -16.250 -12.624 47.690 1.000 43.990  ? 35   MET BBB O    1 
ATOM   3832 C CB   . MET B 2 34  ? -13.849 -10.404 47.194 1.000 54.050  ? 35   MET BBB CB   1 
ATOM   3833 C CG   . MET B 2 34  ? -13.438 -9.297  46.246 1.000 63.570  ? 35   MET BBB CG   1 
ATOM   3834 S SD   . MET B 2 34  ? -11.796 -9.524  45.586 1.000 60.510  ? 35   MET BBB SD   1 
ATOM   3835 C CE   . MET B 2 34  ? -10.866 -8.401  46.623 1.000 58.770  ? 35   MET BBB CE   1 
ATOM   3836 H H    . MET B 2 34  ? -16.306 -10.818 45.859 1.000 41.540  ? 35   MET BBB H    1 
ATOM   3837 H HA   . MET B 2 34  ? -13.708 -12.131 46.040 1.000 42.920  ? 35   MET BBB HA   1 
ATOM   3838 H HB2  . MET B 2 34  ? -14.519 -10.049 47.811 1.000 54.050  ? 35   MET BBB HB2  1 
ATOM   3839 H HB3  . MET B 2 34  ? -13.066 -10.668 47.718 1.000 54.050  ? 35   MET BBB HB3  1 
ATOM   3840 H HG2  . MET B 2 34  ? -14.074 -9.258  45.500 1.000 63.570  ? 35   MET BBB HG2  1 
ATOM   3841 H HG3  . MET B 2 34  ? -13.471 -8.438  46.719 1.000 63.570  ? 35   MET BBB HG3  1 
ATOM   3842 H HE1  . MET B 2 34  ? -9.940  -8.424  46.369 1.000 58.770  ? 35   MET BBB HE1  1 
ATOM   3843 H HE2  . MET B 2 34  ? -11.206 -7.510  46.514 1.000 58.770  ? 35   MET BBB HE2  1 
ATOM   3844 H HE3  . MET B 2 34  ? -10.954 -8.669  47.546 1.000 58.770  ? 35   MET BBB HE3  1 
ATOM   3845 N N    . GLY B 2 35  ? -14.142 -13.205 48.323 1.000 45.360  ? 36   GLY BBB N    1 
ATOM   3846 C CA   . GLY B 2 35  ? -14.468 -14.203 49.353 1.000 48.050  ? 36   GLY BBB CA   1 
ATOM   3847 C C    . GLY B 2 35  ? -13.365 -14.225 50.391 1.000 49.500  ? 36   GLY BBB C    1 
ATOM   3848 O O    . GLY B 2 35  ? -12.207 -13.908 50.035 1.000 55.870  ? 36   GLY BBB O    1 
ATOM   3849 H H    . GLY B 2 35  ? -13.174 -12.981 48.144 1.000 45.360  ? 36   GLY BBB H    1 
ATOM   3850 H HA2  . GLY B 2 35  ? -15.335 -13.967 49.768 1.000 48.050  ? 36   GLY BBB HA2  1 
ATOM   3851 H HA3  . GLY B 2 35  ? -14.563 -15.090 48.925 1.000 48.050  ? 36   GLY BBB HA3  1 
ATOM   3852 N N    . TRP B 2 36  ? -13.719 -14.479 51.646 1.000 45.600  ? 37   TRP BBB N    1 
ATOM   3853 C CA   . TRP B 2 36  ? -12.751 -14.712 52.742 1.000 41.590  ? 37   TRP BBB CA   1 
ATOM   3854 C C    . TRP B 2 36  ? -12.860 -16.200 53.054 1.000 41.650  ? 37   TRP BBB C    1 
ATOM   3855 O O    . TRP B 2 36  ? -13.997 -16.655 53.262 1.000 45.930  ? 37   TRP BBB O    1 
ATOM   3856 C CB   . TRP B 2 36  ? -13.018 -13.836 53.972 1.000 37.440  ? 37   TRP BBB CB   1 
ATOM   3857 C CG   . TRP B 2 36  ? -12.536 -12.429 53.862 1.000 37.150  ? 37   TRP BBB CG   1 
ATOM   3858 C CD1  . TRP B 2 36  ? -13.304 -11.373 53.485 1.000 43.280  ? 37   TRP BBB CD1  1 
ATOM   3859 C CD2  . TRP B 2 36  ? -11.223 -11.881 54.112 1.000 39.650  ? 37   TRP BBB CD2  1 
ATOM   3860 N NE1  . TRP B 2 36  ? -12.580 -10.206 53.487 1.000 44.130  ? 37   TRP BBB NE1  1 
ATOM   3861 C CE2  . TRP B 2 36  ? -11.299 -10.480 53.870 1.000 38.510  ? 37   TRP BBB CE2  1 
ATOM   3862 C CE3  . TRP B 2 36  ? -9.980  -12.414 54.498 1.000 40.860  ? 37   TRP BBB CE3  1 
ATOM   3863 C CZ2  . TRP B 2 36  ? -10.214 -9.618  54.016 1.000 37.650  ? 37   TRP BBB CZ2  1 
ATOM   3864 C CZ3  . TRP B 2 36  ? -8.903  -11.561 54.661 1.000 39.090  ? 37   TRP BBB CZ3  1 
ATOM   3865 C CH2  . TRP B 2 36  ? -9.024  -10.179 54.439 1.000 40.550  ? 37   TRP BBB CH2  1 
ATOM   3866 H H    . TRP B 2 36  ? -14.708 -14.512 51.847 1.000 45.600  ? 37   TRP BBB H    1 
ATOM   3867 H HA   . TRP B 2 36  ? -11.852 -14.485 52.408 1.000 41.590  ? 37   TRP BBB HA   1 
ATOM   3868 H HB2  . TRP B 2 36  ? -13.983 -13.820 54.134 1.000 37.440  ? 37   TRP BBB HB2  1 
ATOM   3869 H HB3  . TRP B 2 36  ? -12.584 -14.252 54.745 1.000 37.440  ? 37   TRP BBB HB3  1 
ATOM   3870 H HD1  . TRP B 2 36  ? -14.219 -11.421 53.254 1.000 43.280  ? 37   TRP BBB HD1  1 
ATOM   3871 H HE1  . TRP B 2 36  ? -12.893 -9.415  53.274 1.000 44.130  ? 37   TRP BBB HE1  1 
ATOM   3872 H HE3  . TRP B 2 36  ? -9.887  -13.338 54.668 1.000 40.860  ? 37   TRP BBB HE3  1 
ATOM   3873 H HZ2  . TRP B 2 36  ? -10.286 -8.696  53.835 1.000 37.650  ? 37   TRP BBB HZ2  1 
ATOM   3874 H HZ3  . TRP B 2 36  ? -8.066  -11.913 54.920 1.000 39.090  ? 37   TRP BBB HZ3  1 
ATOM   3875 H HH2  . TRP B 2 36  ? -8.272  -9.627  54.559 1.000 40.550  ? 37   TRP BBB HH2  1 
ATOM   3876 N N    . PHE B 2 37  ? -11.731 -16.911 53.040 1.000 42.110  ? 38   PHE BBB N    1 
ATOM   3877 C CA   . PHE B 2 37  ? -11.579 -18.343 53.412 1.000 43.420  ? 38   PHE BBB CA   1 
ATOM   3878 C C    . PHE B 2 37  ? -10.690 -18.428 54.653 1.000 47.650  ? 38   PHE BBB C    1 
ATOM   3879 O O    . PHE B 2 37  ? -9.876  -17.485 54.919 1.000 48.830  ? 38   PHE BBB O    1 
ATOM   3880 C CB   . PHE B 2 37  ? -10.891 -19.158 52.317 1.000 40.660  ? 38   PHE BBB CB   1 
ATOM   3881 C CG   . PHE B 2 37  ? -11.705 -19.416 51.077 1.000 41.120  ? 38   PHE BBB CG   1 
ATOM   3882 C CD1  . PHE B 2 37  ? -11.835 -18.452 50.090 1.000 40.550  ? 38   PHE BBB CD1  1 
ATOM   3883 C CD2  . PHE B 2 37  ? -12.307 -20.649 50.878 1.000 42.520  ? 38   PHE BBB CD2  1 
ATOM   3884 C CE1  . PHE B 2 37  ? -12.579 -18.716 48.950 1.000 40.200  ? 38   PHE BBB CE1  1 
ATOM   3885 C CE2  . PHE B 2 37  ? -13.062 -20.904 49.741 1.000 44.510  ? 38   PHE BBB CE2  1 
ATOM   3886 C CZ   . PHE B 2 37  ? -13.199 -19.936 48.776 1.000 41.010  ? 38   PHE BBB CZ   1 
ATOM   3887 H H    . PHE B 2 37  ? -10.918 -16.391 52.741 1.000 42.110  ? 38   PHE BBB H    1 
ATOM   3888 H HA   . PHE B 2 37  ? -12.473 -18.709 53.631 1.000 43.420  ? 38   PHE BBB HA   1 
ATOM   3889 H HB2  . PHE B 2 37  ? -10.070 -18.692 52.053 1.000 40.660  ? 38   PHE BBB HB2  1 
ATOM   3890 H HB3  . PHE B 2 37  ? -10.626 -20.023 52.695 1.000 40.660  ? 38   PHE BBB HB3  1 
ATOM   3891 H HD1  . PHE B 2 37  ? -11.406 -17.617 50.194 1.000 40.550  ? 38   PHE BBB HD1  1 
ATOM   3892 H HD2  . PHE B 2 37  ? -12.199 -21.323 51.530 1.000 42.520  ? 38   PHE BBB HD2  1 
ATOM   3893 H HE1  . PHE B 2 37  ? -12.663 -18.055 48.282 1.000 40.200  ? 38   PHE BBB HE1  1 
ATOM   3894 H HE2  . PHE B 2 37  ? -13.483 -21.742 49.630 1.000 44.510  ? 38   PHE BBB HE2  1 
ATOM   3895 H HZ   . PHE B 2 37  ? -13.702 -20.102 47.995 1.000 41.010  ? 38   PHE BBB HZ   1 
ATOM   3896 N N    . ARG B 2 38  ? -10.784 -19.540 55.377 1.000 45.100  ? 39   ARG BBB N    1 
ATOM   3897 C CA   . ARG B 2 38  ? -9.800  -19.806 56.454 1.000 48.430  ? 39   ARG BBB CA   1 
ATOM   3898 C C    . ARG B 2 38  ? -9.355  -21.268 56.484 1.000 45.770  ? 39   ARG BBB C    1 
ATOM   3899 O O    . ARG B 2 38  ? -10.110 -22.195 56.043 1.000 40.430  ? 39   ARG BBB O    1 
ATOM   3900 C CB   . ARG B 2 38  ? -10.382 -19.428 57.813 1.000 49.910  ? 39   ARG BBB CB   1 
ATOM   3901 C CG   . ARG B 2 38  ? -11.464 -20.378 58.287 1.000 50.970  ? 39   ARG BBB CG   1 
ATOM   3902 C CD   . ARG B 2 38  ? -12.044 -19.852 59.578 1.000 56.550  ? 39   ARG BBB CD   1 
ATOM   3903 N NE   . ARG B 2 38  ? -13.224 -20.617 59.912 1.000 55.310  ? 39   ARG BBB NE   1 
ATOM   3904 C CZ   . ARG B 2 38  ? -14.065 -20.285 60.879 1.000 58.120  ? 39   ARG BBB CZ   1 
ATOM   3905 N NH1  . ARG B 2 38  ? -13.866 -19.185 61.605 1.000 48.850  ? 39   ARG BBB NH1  1 
ATOM   3906 N NH2  . ARG B 2 38  ? -15.117 -21.062 61.082 1.000 54.800  ? 39   ARG BBB NH2  1 
ATOM   3907 H H    . ARG B 2 38  ? -11.519 -20.211 55.205 1.000 45.100  ? 39   ARG BBB H    1 
ATOM   3908 H HA   . ARG B 2 38  ? -8.999  -19.258 56.287 1.000 48.430  ? 39   ARG BBB HA   1 
ATOM   3909 H HB2  . ARG B 2 38  ? -9.655  -19.414 58.470 1.000 49.910  ? 39   ARG BBB HB2  1 
ATOM   3910 H HB3  . ARG B 2 38  ? -10.752 -18.522 57.753 1.000 49.910  ? 39   ARG BBB HB3  1 
ATOM   3911 H HG2  . ARG B 2 38  ? -12.158 -20.448 57.597 1.000 50.970  ? 39   ARG BBB HG2  1 
ATOM   3912 H HG3  . ARG B 2 38  ? -11.077 -21.270 58.418 1.000 50.970  ? 39   ARG BBB HG3  1 
ATOM   3913 H HD2  . ARG B 2 38  ? -11.370 -19.922 60.287 1.000 56.550  ? 39   ARG BBB HD2  1 
ATOM   3914 H HD3  . ARG B 2 38  ? -12.262 -18.902 59.470 1.000 56.550  ? 39   ARG BBB HD3  1 
ATOM   3915 H HE   . ARG B 2 38  ? -13.388 -21.337 59.448 1.000 55.310  ? 39   ARG BBB HE   1 
ATOM   3916 H HH11 . ARG B 2 38  ? -13.170 -18.673 61.442 1.000 48.850  ? 39   ARG BBB HH11 1 
ATOM   3917 H HH12 . ARG B 2 38  ? -14.431 -18.975 62.245 1.000 48.850  ? 39   ARG BBB HH12 1 
ATOM   3918 H HH21 . ARG B 2 38  ? -15.239 -21.775 60.579 1.000 54.800  ? 39   ARG BBB HH21 1 
ATOM   3919 H HH22 . ARG B 2 38  ? -15.692 -20.864 61.719 1.000 54.800  ? 39   ARG BBB HH22 1 
ATOM   3920 N N    . GLN B 2 39  ? -8.155  -21.436 57.023 1.000 43.890  ? 40   GLN BBB N    1 
ATOM   3921 C CA   . GLN B 2 39  ? -7.557  -22.752 57.364 1.000 54.570  ? 40   GLN BBB CA   1 
ATOM   3922 C C    . GLN B 2 39  ? -7.261  -22.754 58.879 1.000 50.300  ? 40   GLN BBB C    1 
ATOM   3923 O O    . GLN B 2 39  ? -6.368  -21.998 59.339 1.000 47.560  ? 40   GLN BBB O    1 
ATOM   3924 C CB   . GLN B 2 39  ? -6.333  -22.979 56.468 1.000 51.870  ? 40   GLN BBB CB   1 
ATOM   3925 C CG   . GLN B 2 39  ? -5.986  -24.445 56.353 1.000 55.110  ? 40   GLN BBB CG   1 
ATOM   3926 C CD   . GLN B 2 39  ? -4.768  -24.678 55.499 1.000 59.540  ? 40   GLN BBB CD   1 
ATOM   3927 O OE1  . GLN B 2 39  ? -4.432  -23.890 54.621 1.000 60.140  ? 40   GLN BBB OE1  1 
ATOM   3928 N NE2  . GLN B 2 39  ? -4.108  -25.797 55.740 1.000 64.190  ? 40   GLN BBB NE2  1 
ATOM   3929 H H    . GLN B 2 39  ? -7.628  -20.594 57.206 1.000 43.890  ? 40   GLN BBB H    1 
ATOM   3930 H HA   . GLN B 2 39  ? -8.213  -23.457 57.155 1.000 54.570  ? 40   GLN BBB HA   1 
ATOM   3931 H HB2  . GLN B 2 39  ? -6.523  -22.608 55.581 1.000 51.870  ? 40   GLN BBB HB2  1 
ATOM   3932 H HB3  . GLN B 2 39  ? -5.576  -22.483 56.843 1.000 51.870  ? 40   GLN BBB HB3  1 
ATOM   3933 H HG2  . GLN B 2 39  ? -5.823  -24.809 57.249 1.000 55.110  ? 40   GLN BBB HG2  1 
ATOM   3934 H HG3  . GLN B 2 39  ? -6.747  -24.927 55.964 1.000 55.110  ? 40   GLN BBB HG3  1 
ATOM   3935 H HE21 . GLN B 2 39  ? -3.384  -25.993 55.273 0.000 64.190  ? 40   GLN BBB HE21 1 
ATOM   3936 H HE22 . GLN B 2 39  ? -4.391  -26.350 56.369 0.000 64.190  ? 40   GLN BBB HE22 1 
ATOM   3937 N N    . ALA B 2 40  ? -8.080  -23.460 59.651 1.000 52.300  ? 41   ALA BBB N    1 
ATOM   3938 C CA   . ALA B 2 40  ? -7.848  -23.669 61.095 1.000 55.040  ? 41   ALA BBB CA   1 
ATOM   3939 C C    . ALA B 2 40  ? -6.943  -24.872 61.250 1.000 57.110  ? 41   ALA BBB C    1 
ATOM   3940 O O    . ALA B 2 40  ? -7.037  -25.783 60.425 1.000 53.650  ? 41   ALA BBB O    1 
ATOM   3941 C CB   . ALA B 2 40  ? -9.146  -23.896 61.813 1.000 57.160  ? 41   ALA BBB CB   1 
ATOM   3942 H H    . ALA B 2 40  ? -8.897  -23.868 59.219 1.000 52.300  ? 41   ALA BBB H    1 
ATOM   3943 H HA   . ALA B 2 40  ? -7.397  -22.871 61.459 1.000 55.040  ? 41   ALA BBB HA   1 
ATOM   3944 H HB1  . ALA B 2 40  ? -8.975  -24.031 62.758 1.000 57.160  ? 41   ALA BBB HB1  1 
ATOM   3945 H HB2  . ALA B 2 40  ? -9.721  -23.123 61.697 1.000 57.160  ? 41   ALA BBB HB2  1 
ATOM   3946 H HB3  . ALA B 2 40  ? -9.586  -24.683 61.449 1.000 57.160  ? 41   ALA BBB HB3  1 
ATOM   3947 N N    . PRO B 2 41  ? -6.114  -24.917 62.329 1.000 67.630  ? 42   PRO BBB N    1 
ATOM   3948 C CA   . PRO B 2 41  ? -5.324  -26.104 62.670 1.000 61.930  ? 42   PRO BBB CA   1 
ATOM   3949 C C    . PRO B 2 41  ? -6.094  -27.409 62.408 1.000 60.870  ? 42   PRO BBB C    1 
ATOM   3950 O O    . PRO B 2 41  ? -7.247  -27.537 62.846 1.000 56.440  ? 42   PRO BBB O    1 
ATOM   3951 C CB   . PRO B 2 41  ? -5.030  -25.926 64.167 1.000 58.490  ? 42   PRO BBB CB   1 
ATOM   3952 C CG   . PRO B 2 41  ? -5.035  -24.418 64.386 1.000 61.610  ? 42   PRO BBB CG   1 
ATOM   3953 C CD   . PRO B 2 41  ? -5.931  -23.829 63.311 1.000 63.380  ? 42   PRO BBB CD   1 
ATOM   3954 H HA   . PRO B 2 41  ? -4.486  -26.101 62.143 1.000 61.930  ? 42   PRO BBB HA   1 
ATOM   3955 H HB2  . PRO B 2 41  ? -5.715  -26.364 64.714 1.000 58.490  ? 42   PRO BBB HB2  1 
ATOM   3956 H HB3  . PRO B 2 41  ? -4.162  -26.314 64.403 1.000 58.490  ? 42   PRO BBB HB3  1 
ATOM   3957 H HG2  . PRO B 2 41  ? -5.380  -24.196 65.276 1.000 61.610  ? 42   PRO BBB HG2  1 
ATOM   3958 H HG3  . PRO B 2 41  ? -4.129  -24.052 64.312 1.000 61.610  ? 42   PRO BBB HG3  1 
ATOM   3959 H HD2  . PRO B 2 41  ? -6.790  -23.547 63.689 1.000 63.380  ? 42   PRO BBB HD2  1 
ATOM   3960 H HD3  . PRO B 2 41  ? -5.511  -23.047 62.896 1.000 63.380  ? 42   PRO BBB HD3  1 
ATOM   3961 N N    . GLY B 2 42  ? -5.474  -28.296 61.621 1.000 59.000  ? 43   GLY BBB N    1 
ATOM   3962 C CA   . GLY B 2 42  ? -5.987  -29.634 61.252 1.000 57.190  ? 43   GLY BBB CA   1 
ATOM   3963 C C    . GLY B 2 42  ? -7.215  -29.631 60.341 1.000 60.940  ? 43   GLY BBB C    1 
ATOM   3964 O O    . GLY B 2 42  ? -7.816  -30.704 60.190 1.000 57.140  ? 43   GLY BBB O    1 
ATOM   3965 H H    . GLY B 2 42  ? -4.579  -27.996 61.263 1.000 59.000  ? 43   GLY BBB H    1 
ATOM   3966 H HA2  . GLY B 2 42  ? -5.272  -30.138 60.789 1.000 57.190  ? 43   GLY BBB HA2  1 
ATOM   3967 H HA3  . GLY B 2 42  ? -6.226  -30.127 62.076 1.000 57.190  ? 43   GLY BBB HA3  1 
ATOM   3968 N N    . LYS B 2 43  ? -7.556  -28.520 59.678 1.000 63.520  ? 44   LYS BBB N    1 
ATOM   3969 C CA   . LYS B 2 43  ? -8.804  -28.426 58.872 1.000 64.960  ? 44   LYS BBB CA   1 
ATOM   3970 C C    . LYS B 2 43  ? -8.550  -27.852 57.465 1.000 53.980  ? 44   LYS BBB C    1 
ATOM   3971 O O    . LYS B 2 43  ? -7.626  -27.015 57.285 1.000 47.640  ? 44   LYS BBB O    1 
ATOM   3972 C CB   . LYS B 2 43  ? -9.789  -27.584 59.682 1.000 73.370  ? 44   LYS BBB CB   1 
ATOM   3973 C CG   . LYS B 2 43  ? -10.107 -28.144 61.066 1.000 75.150  ? 44   LYS BBB CG   1 
ATOM   3974 C CD   . LYS B 2 43  ? -11.211 -27.395 61.789 1.000 87.980  ? 44   LYS BBB CD   1 
ATOM   3975 C CE   . LYS B 2 43  ? -12.549 -27.394 61.073 1.000 99.410  ? 44   LYS BBB CE   1 
ATOM   3976 N NZ   . LYS B 2 43  ? -13.216 -28.715 61.158 1.000 111.240 ? 44   LYS BBB NZ   1 
ATOM   3977 H H    . LYS B 2 43  ? -6.942  -27.720 59.730 1.000 63.520  ? 44   LYS BBB H    1 
ATOM   3978 H HA   . LYS B 2 43  ? -9.171  -29.333 58.757 1.000 64.960  ? 44   LYS BBB HA   1 
ATOM   3979 H HB2  . LYS B 2 43  ? -9.422  -26.680 59.778 1.000 73.370  ? 44   LYS BBB HB2  1 
ATOM   3980 H HB3  . LYS B 2 43  ? -10.621 -27.499 59.171 1.000 73.370  ? 44   LYS BBB HB3  1 
ATOM   3981 H HG2  . LYS B 2 43  ? -10.377 -29.082 60.970 1.000 75.150  ? 44   LYS BBB HG2  1 
ATOM   3982 H HG3  . LYS B 2 43  ? -9.294  -28.107 61.613 1.000 75.150  ? 44   LYS BBB HG3  1 
ATOM   3983 H HD2  . LYS B 2 43  ? -11.341 -27.794 62.676 1.000 87.980  ? 44   LYS BBB HD2  1 
ATOM   3984 H HD3  . LYS B 2 43  ? -10.934 -26.463 61.918 1.000 87.980  ? 44   LYS BBB HD3  1 
ATOM   3985 H HE2  . LYS B 2 43  ? -13.131 -26.718 61.468 1.000 99.410  ? 44   LYS BBB HE2  1 
ATOM   3986 H HE3  . LYS B 2 43  ? -12.417 -27.164 60.134 1.000 99.410  ? 44   LYS BBB HE3  1 
ATOM   3987 H HZ1  . LYS B 2 43  ? -12.690 -29.349 60.779 1.000 111.240 ? 44   LYS BBB HZ1  1 
ATOM   3988 H HZ2  . LYS B 2 43  ? -14.012 -28.685 60.725 1.000 111.240 ? 44   LYS BBB HZ2  1 
ATOM   3989 H HZ3  . LYS B 2 43  ? -13.360 -28.931 62.027 1.000 111.240 ? 44   LYS BBB HZ3  1 
ATOM   3990 N N    . GLY B 2 44  ? -9.388  -28.254 56.506 1.000 53.640  ? 45   GLY BBB N    1 
ATOM   3991 C CA   . GLY B 2 44  ? -9.382  -27.723 55.121 1.000 53.880  ? 45   GLY BBB CA   1 
ATOM   3992 C C    . GLY B 2 44  ? -9.736  -26.241 55.056 1.000 47.820  ? 45   GLY BBB C    1 
ATOM   3993 O O    . GLY B 2 44  ? -10.161 -25.664 56.069 1.000 50.390  ? 45   GLY BBB O    1 
ATOM   3994 H H    . GLY B 2 44  ? -10.022 -29.017 56.694 1.000 53.640  ? 45   GLY BBB H    1 
ATOM   3995 H HA2  . GLY B 2 44  ? -8.483  -27.855 54.728 1.000 53.880  ? 45   GLY BBB HA2  1 
ATOM   3996 H HA3  . GLY B 2 44  ? -10.033 -28.232 54.577 1.000 53.880  ? 45   GLY BBB HA3  1 
ATOM   3997 N N    . ARG B 2 45  ? -9.532  -25.622 53.902 1.000 48.270  ? 46   ARG BBB N    1 
ATOM   3998 C CA   . ARG B 2 45  ? -9.964  -24.232 53.617 1.000 46.880  ? 46   ARG BBB CA   1 
ATOM   3999 C C    . ARG B 2 45  ? -11.488 -24.189 53.669 1.000 47.840  ? 46   ARG BBB C    1 
ATOM   4000 O O    . ARG B 2 45  ? -12.127 -24.967 52.947 1.000 48.460  ? 46   ARG BBB O    1 
ATOM   4001 C CB   . ARG B 2 45  ? -9.504  -23.751 52.238 1.000 49.520  ? 46   ARG BBB CB   1 
ATOM   4002 C CG   . ARG B 2 45  ? -8.404  -22.701 52.289 1.000 53.010  ? 46   ARG BBB CG   1 
ATOM   4003 C CD   . ARG B 2 45  ? -7.921  -22.367 50.893 1.000 51.940  ? 46   ARG BBB CD   1 
ATOM   4004 N NE   . ARG B 2 45  ? -7.287  -23.503 50.231 1.000 53.280  ? 46   ARG BBB NE   1 
ATOM   4005 C CZ   . ARG B 2 45  ? -6.891  -23.531 48.954 1.000 52.970  ? 46   ARG BBB CZ   1 
ATOM   4006 N NH1  . ARG B 2 45  ? -7.090  -22.495 48.158 1.000 54.050  ? 46   ARG BBB NH1  1 
ATOM   4007 N NH2  . ARG B 2 45  ? -6.327  -24.616 48.464 1.000 49.000  ? 46   ARG BBB NH2  1 
ATOM   4008 H H    . ARG B 2 45  ? -9.051  -26.145 53.184 1.000 48.270  ? 46   ARG BBB H    1 
ATOM   4009 H HA   . ARG B 2 45  ? -9.597  -23.642 54.315 1.000 46.880  ? 46   ARG BBB HA   1 
ATOM   4010 H HB2  . ARG B 2 45  ? -9.182  -24.524 51.729 1.000 49.520  ? 46   ARG BBB HB2  1 
ATOM   4011 H HB3  . ARG B 2 45  ? -10.277 -23.379 51.764 1.000 49.520  ? 46   ARG BBB HB3  1 
ATOM   4012 H HG2  . ARG B 2 45  ? -8.748  -21.893 52.725 1.000 53.010  ? 46   ARG BBB HG2  1 
ATOM   4013 H HG3  . ARG B 2 45  ? -7.658  -23.040 52.828 1.000 53.010  ? 46   ARG BBB HG3  1 
ATOM   4014 H HD2  . ARG B 2 45  ? -8.682  -22.065 50.352 1.000 51.940  ? 46   ARG BBB HD2  1 
ATOM   4015 H HD3  . ARG B 2 45  ? -7.280  -21.626 50.942 1.000 51.940  ? 46   ARG BBB HD3  1 
ATOM   4016 H HE   . ARG B 2 45  ? -7.152  -24.225 50.700 1.000 53.280  ? 46   ARG BBB HE   1 
ATOM   4017 H HH11 . ARG B 2 45  ? -7.488  -21.775 48.468 1.000 54.050  ? 46   ARG BBB HH11 1 
ATOM   4018 H HH12 . ARG B 2 45  ? -6.824  -22.529 47.321 1.000 54.050  ? 46   ARG BBB HH12 1 
ATOM   4019 H HH21 . ARG B 2 45  ? -6.212  -25.321 48.979 1.000 49.000  ? 46   ARG BBB HH21 1 
ATOM   4020 H HH22 . ARG B 2 45  ? -6.067  -24.633 47.623 1.000 49.000  ? 46   ARG BBB HH22 1 
ATOM   4021 N N    . GLU B 2 46  ? -12.024 -23.262 54.445 1.000 45.420  ? 47   GLU BBB N    1 
ATOM   4022 C CA   . GLU B 2 46  ? -13.475 -22.987 54.549 1.000 49.010  ? 47   GLU BBB CA   1 
ATOM   4023 C C    . GLU B 2 46  ? -13.817 -21.580 54.026 1.000 46.490  ? 47   GLU BBB C    1 
ATOM   4024 O O    . GLU B 2 46  ? -13.211 -20.578 54.524 1.000 43.140  ? 47   GLU BBB O    1 
ATOM   4025 C CB   . GLU B 2 46  ? -13.831 -23.052 56.026 1.000 53.180  ? 47   GLU BBB CB   1 
ATOM   4026 C CG   . GLU B 2 46  ? -15.263 -23.440 56.251 1.000 63.280  ? 47   GLU BBB CG   1 
ATOM   4027 C CD   . GLU B 2 46  ? -15.733 -23.247 57.672 1.000 57.960  ? 47   GLU BBB CD   1 
ATOM   4028 O OE1  . GLU B 2 46  ? -14.892 -22.949 58.557 1.000 57.610  ? 47   GLU BBB OE1  1 
ATOM   4029 O OE2  . GLU B 2 46  ? -16.945 -23.337 57.852 1.000 61.650  ? 47   GLU BBB OE2  1 
ATOM   4030 H H    . GLU B 2 46  ? -11.378 -22.715 54.997 1.000 45.420  ? 47   GLU BBB H    1 
ATOM   4031 H HA   . GLU B 2 46  ? -13.958 -23.641 53.993 1.000 49.010  ? 47   GLU BBB HA   1 
ATOM   4032 H HB2  . GLU B 2 46  ? -13.244 -23.706 56.460 1.000 53.180  ? 47   GLU BBB HB2  1 
ATOM   4033 H HB3  . GLU B 2 46  ? -13.664 -22.173 56.426 1.000 53.180  ? 47   GLU BBB HB3  1 
ATOM   4034 H HG2  . GLU B 2 46  ? -15.834 -22.909 55.655 1.000 63.280  ? 47   GLU BBB HG2  1 
ATOM   4035 H HG3  . GLU B 2 46  ? -15.379 -24.383 56.005 1.000 63.280  ? 47   GLU BBB HG3  1 
ATOM   4036 N N    . LEU B 2 47  ? -14.790 -21.471 53.122 1.000 43.390  ? 48   LEU BBB N    1 
ATOM   4037 C CA   . LEU B 2 47  ? -15.385 -20.148 52.777 1.000 47.650  ? 48   LEU BBB CA   1 
ATOM   4038 C C    . LEU B 2 47  ? -16.190 -19.664 53.997 1.000 43.630  ? 48   LEU BBB C    1 
ATOM   4039 O O    . LEU B 2 47  ? -17.103 -20.384 54.418 1.000 48.830  ? 48   LEU BBB O    1 
ATOM   4040 C CB   . LEU B 2 47  ? -16.263 -20.249 51.516 1.000 47.620  ? 48   LEU BBB CB   1 
ATOM   4041 C CG   . LEU B 2 47  ? -16.839 -18.921 50.984 1.000 45.360  ? 48   LEU BBB CG   1 
ATOM   4042 C CD1  . LEU B 2 47  ? -15.765 -17.976 50.497 1.000 45.130  ? 48   LEU BBB CD1  1 
ATOM   4043 C CD2  . LEU B 2 47  ? -17.818 -19.152 49.861 1.000 44.540  ? 48   LEU BBB CD2  1 
ATOM   4044 H H    . LEU B 2 47  ? -15.133 -22.301 52.660 1.000 43.390  ? 48   LEU BBB H    1 
ATOM   4045 H HA   . LEU B 2 47  ? -14.653 -19.515 52.593 1.000 47.650  ? 48   LEU BBB HA   1 
ATOM   4046 H HB2  . LEU B 2 47  ? -15.732 -20.658 50.804 1.000 47.620  ? 48   LEU BBB HB2  1 
ATOM   4047 H HB3  . LEU B 2 47  ? -17.010 -20.850 51.709 1.000 47.620  ? 48   LEU BBB HB3  1 
ATOM   4048 H HG   . LEU B 2 47  ? -17.327 -18.481 51.723 1.000 45.360  ? 48   LEU BBB HG   1 
ATOM   4049 H HD11 . LEU B 2 47  ? -15.159 -17.768 51.230 1.000 45.130  ? 48   LEU BBB HD11 1 
ATOM   4050 H HD12 . LEU B 2 47  ? -16.177 -17.157 50.172 1.000 45.130  ? 48   LEU BBB HD12 1 
ATOM   4051 H HD13 . LEU B 2 47  ? -15.266 -18.396 49.775 1.000 45.130  ? 48   LEU BBB HD13 1 
ATOM   4052 H HD21 . LEU B 2 47  ? -17.370 -19.609 49.128 1.000 44.540  ? 48   LEU BBB HD21 1 
ATOM   4053 H HD22 . LEU B 2 47  ? -18.162 -18.297 49.550 1.000 44.540  ? 48   LEU BBB HD22 1 
ATOM   4054 H HD23 . LEU B 2 47  ? -18.555 -19.700 50.181 1.000 44.540  ? 48   LEU BBB HD23 1 
ATOM   4055 N N    . VAL B 2 48  ? -15.852 -18.507 54.568 1.000 39.010  ? 49   VAL BBB N    1 
ATOM   4056 C CA   . VAL B 2 48  ? -16.647 -17.925 55.687 1.000 45.000  ? 49   VAL BBB CA   1 
ATOM   4057 C C    . VAL B 2 48  ? -17.517 -16.746 55.204 1.000 46.850  ? 49   VAL BBB C    1 
ATOM   4058 O O    . VAL B 2 48  ? -18.451 -16.420 55.933 1.000 44.290  ? 49   VAL BBB O    1 
ATOM   4059 C CB   . VAL B 2 48  ? -15.746 -17.533 56.882 1.000 51.080  ? 49   VAL BBB CB   1 
ATOM   4060 C CG1  . VAL B 2 48  ? -15.091 -18.752 57.510 1.000 48.450  ? 49   VAL BBB CG1  1 
ATOM   4061 C CG2  . VAL B 2 48  ? -14.704 -16.479 56.540 1.000 53.180  ? 49   VAL BBB CG2  1 
ATOM   4062 H H    . VAL B 2 48  ? -15.037 -18.013 54.234 1.000 39.010  ? 49   VAL BBB H    1 
ATOM   4063 H HA   . VAL B 2 48  ? -17.250 -18.611 56.025 1.000 45.000  ? 49   VAL BBB HA   1 
ATOM   4064 H HB   . VAL B 2 48  ? -16.332 -17.140 57.575 1.000 51.080  ? 49   VAL BBB HB   1 
ATOM   4065 H HG11 . VAL B 2 48  ? -15.779 -19.362 57.830 1.000 48.450  ? 49   VAL BBB HG11 1 
ATOM   4066 H HG12 . VAL B 2 48  ? -14.532 -18.473 58.256 1.000 48.450  ? 49   VAL BBB HG12 1 
ATOM   4067 H HG13 . VAL B 2 48  ? -14.542 -19.204 56.846 1.000 48.450  ? 49   VAL BBB HG13 1 
ATOM   4068 H HG21 . VAL B 2 48  ? -14.122 -16.814 55.835 1.000 53.180  ? 49   VAL BBB HG21 1 
ATOM   4069 H HG22 . VAL B 2 48  ? -14.174 -16.278 57.331 1.000 53.180  ? 49   VAL BBB HG22 1 
ATOM   4070 H HG23 . VAL B 2 48  ? -15.149 -15.669 56.235 1.000 53.180  ? 49   VAL BBB HG23 1 
ATOM   4071 N N    . ALA B 2 49  ? -17.268 -16.144 54.025 1.000 43.990  ? 50   ALA BBB N    1 
ATOM   4072 C CA   . ALA B 2 49  ? -17.946 -14.902 53.581 1.000 41.240  ? 50   ALA BBB CA   1 
ATOM   4073 C C    . ALA B 2 49  ? -17.646 -14.632 52.094 1.000 45.660  ? 50   ALA BBB C    1 
ATOM   4074 O O    . ALA B 2 49  ? -16.470 -14.769 51.653 1.000 45.040  ? 50   ALA BBB O    1 
ATOM   4075 C CB   . ALA B 2 49  ? -17.520 -13.747 54.495 1.000 39.880  ? 50   ALA BBB CB   1 
ATOM   4076 H H    . ALA B 2 49  ? -16.581 -16.572 53.422 1.000 43.990  ? 50   ALA BBB H    1 
ATOM   4077 H HA   . ALA B 2 49  ? -18.919 -15.023 53.682 1.000 41.240  ? 50   ALA BBB HA   1 
ATOM   4078 H HB1  . ALA B 2 49  ? -17.959 -12.930 54.211 1.000 39.880  ? 50   ALA BBB HB1  1 
ATOM   4079 H HB2  . ALA B 2 49  ? -17.772 -13.947 55.410 1.000 39.880  ? 50   ALA BBB HB2  1 
ATOM   4080 H HB3  . ALA B 2 49  ? -16.556 -13.630 54.444 1.000 39.880  ? 50   ALA BBB HB3  1 
ATOM   4081 N N    . ALA B 2 50  ? -18.667 -14.253 51.329 1.000 42.860  ? 51   ALA BBB N    1 
ATOM   4082 C CA   . ALA B 2 50  ? -18.561 -13.922 49.886 1.000 40.860  ? 51   ALA BBB CA   1 
ATOM   4083 C C    . ALA B 2 50  ? -19.425 -12.693 49.569 1.000 40.530  ? 51   ALA BBB C    1 
ATOM   4084 O O    . ALA B 2 50  ? -20.463 -12.493 50.246 1.000 41.880  ? 51   ALA BBB O    1 
ATOM   4085 C CB   . ALA B 2 50  ? -18.983 -15.120 49.062 1.000 40.310  ? 51   ALA BBB CB   1 
ATOM   4086 H H    . ALA B 2 50  ? -19.567 -14.193 51.783 1.000 42.860  ? 51   ALA BBB H    1 
ATOM   4087 H HA   . ALA B 2 50  ? -17.621 -13.704 49.683 1.000 40.860  ? 51   ALA BBB HA   1 
ATOM   4088 H HB1  . ALA B 2 50  ? -18.914 -14.905 48.119 1.000 40.310  ? 51   ALA BBB HB1  1 
ATOM   4089 H HB2  . ALA B 2 50  ? -18.405 -15.873 49.264 1.000 40.310  ? 51   ALA BBB HB2  1 
ATOM   4090 H HB3  . ALA B 2 50  ? -19.903 -15.353 49.274 1.000 40.310  ? 51   ALA BBB HB3  1 
ATOM   4091 N N    . ILE B 2 51  ? -19.022 -11.910 48.571 1.000 38.910  ? 52   ILE BBB N    1 
ATOM   4092 C CA   . ILE B 2 51  ? -19.650 -10.609 48.202 1.000 39.740  ? 52   ILE BBB CA   1 
ATOM   4093 C C    . ILE B 2 51  ? -19.618 -10.428 46.672 1.000 39.990  ? 52   ILE BBB C    1 
ATOM   4094 O O    . ILE B 2 51  ? -18.635 -10.736 46.043 1.000 36.350  ? 52   ILE BBB O    1 
ATOM   4095 C CB   . ILE B 2 51  ? -18.959 -9.458  48.979 1.000 41.270  ? 52   ILE BBB CB   1 
ATOM   4096 C CG1  . ILE B 2 51  ? -19.719 -8.141  48.839 1.000 43.080  ? 52   ILE BBB CG1  1 
ATOM   4097 C CG2  . ILE B 2 51  ? -17.502 -9.296  48.581 1.000 41.010  ? 52   ILE BBB CG2  1 
ATOM   4098 C CD1  . ILE B 2 51  ? -19.363 -7.125  49.901 1.000 44.920  ? 52   ILE BBB CD1  1 
ATOM   4099 H H    . ILE B 2 51  ? -18.231 -12.243 48.039 1.000 38.910  ? 52   ILE BBB H    1 
ATOM   4100 H HA   . ILE B 2 51  ? -20.582 -10.627 48.484 1.000 39.740  ? 52   ILE BBB HA   1 
ATOM   4101 H HB   . ILE B 2 51  ? -18.972 -9.699  49.938 1.000 41.270  ? 52   ILE BBB HB   1 
ATOM   4102 H HG12 . ILE B 2 51  ? -19.528 -7.760  47.956 1.000 43.080  ? 52   ILE BBB HG12 1 
ATOM   4103 H HG13 . ILE B 2 51  ? -20.681 -8.327  48.885 1.000 43.080  ? 52   ILE BBB HG13 1 
ATOM   4104 H HG21 . ILE B 2 51  ? -17.018 -10.118 48.770 1.000 41.010  ? 52   ILE BBB HG21 1 
ATOM   4105 H HG22 . ILE B 2 51  ? -17.103 -8.569  49.089 1.000 41.010  ? 52   ILE BBB HG22 1 
ATOM   4106 H HG23 . ILE B 2 51  ? -17.442 -9.097  47.630 1.000 41.010  ? 52   ILE BBB HG23 1 
ATOM   4107 H HD11 . ILE B 2 51  ? -19.568 -7.487  50.780 1.000 44.920  ? 52   ILE BBB HD11 1 
ATOM   4108 H HD12 . ILE B 2 51  ? -19.877 -6.311  49.759 1.000 44.920  ? 52   ILE BBB HD12 1 
ATOM   4109 H HD13 . ILE B 2 51  ? -18.413 -6.920  49.850 1.000 44.920  ? 52   ILE BBB HD13 1 
ATOM   4110 N N    . SER B 2 52  ? -20.720 -9.986  46.098 1.000 43.640  ? 53   SER BBB N    1 
ATOM   4111 C CA   . SER B 2 52  ? -20.868 -9.617  44.675 1.000 41.830  ? 53   SER BBB CA   1 
ATOM   4112 C C    . SER B 2 52  ? -19.886 -8.494  44.375 1.000 38.270  ? 53   SER BBB C    1 
ATOM   4113 O O    . SER B 2 52  ? -19.357 -7.919  45.311 1.000 40.810  ? 53   SER BBB O    1 
ATOM   4114 C CB   . SER B 2 52  ? -22.282 -9.154  44.410 1.000 45.370  ? 53   SER BBB CB   1 
ATOM   4115 O OG   . SER B 2 52  ? -22.558 -7.951  45.141 1.000 39.730  ? 53   SER BBB OG   1 
ATOM   4116 H H    . SER B 2 52  ? -21.517 -9.904  46.714 1.000 43.640  ? 53   SER BBB H    1 
ATOM   4117 H HA   . SER B 2 52  ? -20.632 -10.411 44.124 1.000 41.830  ? 53   SER BBB HA   1 
ATOM   4118 H HB2  . SER B 2 52  ? -22.395 -8.989  43.447 1.000 45.370  ? 53   SER BBB HB2  1 
ATOM   4119 H HB3  . SER B 2 52  ? -22.912 -9.859  44.683 1.000 45.370  ? 53   SER BBB HB3  1 
ATOM   4120 H HG   . SER B 2 52  ? -23.353 -7.713  44.976 0.000 39.730  ? 53   SER BBB HG   1 
ATOM   4121 N N    . ARG B 2 53  ? -19.731 -8.179  43.100 1.000 40.220  ? 54   ARG BBB N    1 
ATOM   4122 C CA   . ARG B 2 53  ? -18.927 -7.048  42.570 1.000 40.770  ? 54   ARG BBB CA   1 
ATOM   4123 C C    . ARG B 2 53  ? -19.374 -5.720  43.195 1.000 42.130  ? 54   ARG BBB C    1 
ATOM   4124 O O    . ARG B 2 53  ? -18.510 -4.901  43.548 1.000 43.370  ? 54   ARG BBB O    1 
ATOM   4125 C CB   . ARG B 2 53  ? -19.070 -7.036  41.041 1.000 40.100  ? 54   ARG BBB CB   1 
ATOM   4126 C CG   . ARG B 2 53  ? -18.642 -5.737  40.367 1.000 38.030  ? 54   ARG BBB CG   1 
ATOM   4127 C CD   . ARG B 2 53  ? -18.471 -5.862  38.883 1.000 33.920  ? 54   ARG BBB CD   1 
ATOM   4128 N NE   . ARG B 2 53  ? -17.246 -6.545  38.557 1.000 33.770  ? 54   ARG BBB NE   1 
ATOM   4129 C CZ   . ARG B 2 53  ? -17.150 -7.670  37.866 1.000 34.330  ? 54   ARG BBB CZ   1 
ATOM   4130 N NH1  . ARG B 2 53  ? -18.209 -8.325  37.416 1.000 38.010  ? 54   ARG BBB NH1  1 
ATOM   4131 N NH2  . ARG B 2 53  ? -15.963 -8.186  37.672 1.000 35.950  ? 54   ARG BBB NH2  1 
ATOM   4132 H H    . ARG B 2 53  ? -20.217 -8.783  42.453 1.000 40.220  ? 54   ARG BBB H    1 
ATOM   4133 H HA   . ARG B 2 53  ? -17.983 -7.196  42.810 1.000 40.770  ? 54   ARG BBB HA   1 
ATOM   4134 H HB2  . ARG B 2 53  ? -18.532 -7.767  40.672 1.000 40.100  ? 54   ARG BBB HB2  1 
ATOM   4135 H HB3  . ARG B 2 53  ? -20.008 -7.207  40.814 1.000 40.100  ? 54   ARG BBB HB3  1 
ATOM   4136 H HG2  . ARG B 2 53  ? -19.314 -5.044  40.544 1.000 38.030  ? 54   ARG BBB HG2  1 
ATOM   4137 H HG3  . ARG B 2 53  ? -17.791 -5.438  40.752 1.000 38.030  ? 54   ARG BBB HG3  1 
ATOM   4138 H HD2  . ARG B 2 53  ? -19.235 -6.352  38.510 1.000 33.920  ? 54   ARG BBB HD2  1 
ATOM   4139 H HD3  . ARG B 2 53  ? -18.470 -4.967  38.482 1.000 33.920  ? 54   ARG BBB HD3  1 
ATOM   4140 H HE   . ARG B 2 53  ? -16.497 -6.195  38.835 1.000 33.770  ? 54   ARG BBB HE   1 
ATOM   4141 H HH11 . ARG B 2 53  ? -19.016 -8.014  37.574 1.000 38.010  ? 54   ARG BBB HH11 1 
ATOM   4142 H HH12 . ARG B 2 53  ? -18.102 -9.069  36.961 1.000 38.010  ? 54   ARG BBB HH12 1 
ATOM   4143 H HH21 . ARG B 2 53  ? -15.251 -7.784  37.999 1.000 35.950  ? 54   ARG BBB HH21 1 
ATOM   4144 H HH22 . ARG B 2 53  ? -15.879 -8.934  37.215 1.000 35.950  ? 54   ARG BBB HH22 1 
ATOM   4145 N N    . THR B 2 54  ? -20.676 -5.461  43.255 1.000 40.660  ? 55   THR BBB N    1 
ATOM   4146 C CA   . THR B 2 54  ? -21.206 -4.161  43.738 1.000 39.380  ? 55   THR BBB CA   1 
ATOM   4147 C C    . THR B 2 54  ? -21.300 -4.143  45.262 1.000 41.340  ? 55   THR BBB C    1 
ATOM   4148 O O    . THR B 2 54  ? -21.294 -3.044  45.805 1.000 43.490  ? 55   THR BBB O    1 
ATOM   4149 C CB   . THR B 2 54  ? -22.587 -3.833  43.162 1.000 37.660  ? 55   THR BBB CB   1 
ATOM   4150 O OG1  . THR B 2 54  ? -23.478 -4.917  43.401 1.000 42.610  ? 55   THR BBB OG1  1 
ATOM   4151 C CG2  . THR B 2 54  ? -22.512 -3.517  41.691 1.000 34.970  ? 55   THR BBB CG2  1 
ATOM   4152 H H    . THR B 2 54  ? -21.324 -6.178  42.960 1.000 40.660  ? 55   THR BBB H    1 
ATOM   4153 H HA   . THR B 2 54  ? -20.576 -3.455  43.465 1.000 39.380  ? 55   THR BBB HA   1 
ATOM   4154 H HB   . THR B 2 54  ? -22.948 -3.054  43.648 1.000 37.660  ? 55   THR BBB HB   1 
ATOM   4155 H HG1  . THR B 2 54  ? -24.242 -4.733  43.081 0.000 42.610  ? 55   THR BBB HG1  1 
ATOM   4156 H HG21 . THR B 2 54  ? -21.931 -2.747  41.552 1.000 34.970  ? 55   THR BBB HG21 1 
ATOM   4157 H HG22 . THR B 2 54  ? -23.403 -3.312  41.356 1.000 34.970  ? 55   THR BBB HG22 1 
ATOM   4158 H HG23 . THR B 2 54  ? -22.153 -4.284  41.210 1.000 34.970  ? 55   THR BBB HG23 1 
ATOM   4159 N N    . GLY B 2 55  ? -21.378 -5.303  45.921 1.000 43.440  ? 56   GLY BBB N    1 
ATOM   4160 C CA   . GLY B 2 55  ? -21.549 -5.385  47.376 1.000 39.780  ? 56   GLY BBB CA   1 
ATOM   4161 C C    . GLY B 2 55  ? -23.014 -5.489  47.732 1.000 43.320  ? 56   GLY BBB C    1 
ATOM   4162 O O    . GLY B 2 55  ? -23.319 -5.516  48.912 1.000 50.280  ? 56   GLY BBB O    1 
ATOM   4163 H H    . GLY B 2 55  ? -21.315 -6.156  45.384 1.000 43.440  ? 56   GLY BBB H    1 
ATOM   4164 H HA2  . GLY B 2 55  ? -21.061 -6.177  47.715 1.000 39.780  ? 56   GLY BBB HA2  1 
ATOM   4165 H HA3  . GLY B 2 55  ? -21.155 -4.579  47.794 1.000 39.780  ? 56   GLY BBB HA3  1 
ATOM   4166 N N    . GLY B 2 56  ? -23.904 -5.603  46.754 1.000 45.870  ? 57   GLY BBB N    1 
ATOM   4167 C CA   . GLY B 2 56  ? -25.350 -5.645  47.034 1.000 45.850  ? 57   GLY BBB CA   1 
ATOM   4168 C C    . GLY B 2 56  ? -25.810 -7.013  47.509 1.000 45.070  ? 57   GLY BBB C    1 
ATOM   4169 O O    . GLY B 2 56  ? -26.985 -7.144  47.899 1.000 44.190  ? 57   GLY BBB O    1 
ATOM   4170 H H    . GLY B 2 56  ? -23.586 -5.662  45.797 1.000 45.870  ? 57   GLY BBB H    1 
ATOM   4171 H HA2  . GLY B 2 56  ? -25.564 -4.973  47.729 1.000 45.850  ? 57   GLY BBB HA2  1 
ATOM   4172 H HA3  . GLY B 2 56  ? -25.846 -5.405  46.211 1.000 45.850  ? 57   GLY BBB HA3  1 
ATOM   4173 N N    . SER B 2 57  ? -24.936 -8.013  47.441 1.000 44.570  ? 58   SER BBB N    1 
ATOM   4174 C CA   . SER B 2 57  ? -25.244 -9.427  47.777 1.000 47.920  ? 58   SER BBB CA   1 
ATOM   4175 C C    . SER B 2 57  ? -24.073 -10.048 48.551 1.000 45.860  ? 58   SER BBB C    1 
ATOM   4176 O O    . SER B 2 57  ? -22.898 -9.757  48.222 1.000 45.760  ? 58   SER BBB O    1 
ATOM   4177 C CB   . SER B 2 57  ? -25.570 -10.210 46.535 1.000 44.290  ? 58   SER BBB CB   1 
ATOM   4178 O OG   . SER B 2 57  ? -26.707 -9.656  45.934 1.000 53.100  ? 58   SER BBB OG   1 
ATOM   4179 H H    . SER B 2 57  ? -24.004 -7.771  47.137 1.000 44.570  ? 58   SER BBB H    1 
ATOM   4180 H HA   . SER B 2 57  ? -26.046 -9.436  48.366 1.000 47.920  ? 58   SER BBB HA   1 
ATOM   4181 H HB2  . SER B 2 57  ? -24.805 -10.174 45.918 1.000 44.290  ? 58   SER BBB HB2  1 
ATOM   4182 H HB3  . SER B 2 57  ? -25.734 -11.150 46.777 1.000 44.290  ? 58   SER BBB HB3  1 
ATOM   4183 H HG   . SER B 2 57  ? -26.886 -10.100 45.236 0.000 53.100  ? 58   SER BBB HG   1 
ATOM   4184 N N    . THR B 2 58  ? -24.393 -10.834 49.573 1.000 42.590  ? 59   THR BBB N    1 
ATOM   4185 C CA   . THR B 2 58  ? -23.399 -11.447 50.483 1.000 43.370  ? 59   THR BBB CA   1 
ATOM   4186 C C    . THR B 2 58  ? -23.834 -12.877 50.758 1.000 42.630  ? 59   THR BBB C    1 
ATOM   4187 O O    . THR B 2 58  ? -24.974 -13.204 50.443 1.000 39.660  ? 59   THR BBB O    1 
ATOM   4188 C CB   . THR B 2 58  ? -23.136 -10.610 51.736 1.000 44.040  ? 59   THR BBB CB   1 
ATOM   4189 O OG1  . THR B 2 58  ? -24.303 -10.607 52.552 1.000 46.110  ? 59   THR BBB OG1  1 
ATOM   4190 C CG2  . THR B 2 58  ? -22.674 -9.202  51.408 1.000 44.250  ? 59   THR BBB CG2  1 
ATOM   4191 H H    . THR B 2 58  ? -25.375 -11.014 49.724 1.000 42.590  ? 59   THR BBB H    1 
ATOM   4192 H HA   . THR B 2 58  ? -22.528 -11.455 50.023 1.000 43.370  ? 59   THR BBB HA   1 
ATOM   4193 H HB   . THR B 2 58  ? -22.438 -11.061 52.269 1.000 44.040  ? 59   THR BBB HB   1 
ATOM   4194 H HG1  . THR B 2 58  ? -24.162 -10.144 53.248 0.000 46.110  ? 59   THR BBB HG1  1 
ATOM   4195 H HG21 . THR B 2 58  ? -21.846 -9.241  50.896 1.000 44.250  ? 59   THR BBB HG21 1 
ATOM   4196 H HG22 . THR B 2 58  ? -22.519 -8.709  52.234 1.000 44.250  ? 59   THR BBB HG22 1 
ATOM   4197 H HG23 . THR B 2 58  ? -23.358 -8.748  50.883 1.000 44.250  ? 59   THR BBB HG23 1 
ATOM   4198 N N    . TYR B 2 59  ? -22.871 -13.732 51.095 1.000 45.100  ? 60   TYR BBB N    1 
ATOM   4199 C CA   . TYR B 2 59  ? -23.100 -15.148 51.468 1.000 40.650  ? 60   TYR BBB CA   1 
ATOM   4200 C C    . TYR B 2 59  ? -22.189 -15.445 52.649 1.000 42.540  ? 60   TYR BBB C    1 
ATOM   4201 O O    . TYR B 2 59  ? -20.992 -15.067 52.611 1.000 43.920  ? 60   TYR BBB O    1 
ATOM   4202 C CB   . TYR B 2 59  ? -22.873 -16.116 50.309 1.000 42.060  ? 60   TYR BBB CB   1 
ATOM   4203 C CG   . TYR B 2 59  ? -22.767 -17.522 50.811 1.000 41.770  ? 60   TYR BBB CG   1 
ATOM   4204 C CD1  . TYR B 2 59  ? -23.897 -18.315 50.935 1.000 46.040  ? 60   TYR BBB CD1  1 
ATOM   4205 C CD2  . TYR B 2 59  ? -21.551 -18.018 51.269 1.000 43.060  ? 60   TYR BBB CD2  1 
ATOM   4206 C CE1  . TYR B 2 59  ? -23.823 -19.587 51.487 1.000 48.900  ? 60   TYR BBB CE1  1 
ATOM   4207 C CE2  . TYR B 2 59  ? -21.451 -19.290 51.805 1.000 43.920  ? 60   TYR BBB CE2  1 
ATOM   4208 C CZ   . TYR B 2 59  ? -22.596 -20.068 51.929 1.000 49.090  ? 60   TYR BBB CZ   1 
ATOM   4209 O OH   . TYR B 2 59  ? -22.519 -21.322 52.458 1.000 54.690  ? 60   TYR BBB OH   1 
ATOM   4210 H H    . TYR B 2 59  ? -21.928 -13.371 51.090 1.000 45.100  ? 60   TYR BBB H    1 
ATOM   4211 H HA   . TYR B 2 59  ? -24.047 -15.254 51.742 1.000 40.650  ? 60   TYR BBB HA   1 
ATOM   4212 H HB2  . TYR B 2 59  ? -23.617 -16.023 49.678 1.000 42.060  ? 60   TYR BBB HB2  1 
ATOM   4213 H HB3  . TYR B 2 59  ? -22.057 -15.849 49.837 1.000 42.060  ? 60   TYR BBB HB3  1 
ATOM   4214 H HD1  . TYR B 2 59  ? -24.738 -17.960 50.699 1.000 46.040  ? 60   TYR BBB HD1  1 
ATOM   4215 H HD2  . TYR B 2 59  ? -20.779 -17.480 51.214 1.000 43.060  ? 60   TYR BBB HD2  1 
ATOM   4216 H HE1  . TYR B 2 59  ? -24.600 -20.116 51.565 1.000 48.900  ? 60   TYR BBB HE1  1 
ATOM   4217 H HE2  . TYR B 2 59  ? -20.621 -19.621 52.106 1.000 43.920  ? 60   TYR BBB HE2  1 
ATOM   4218 H HH   . TYR B 2 59  ? -22.771 -21.902 51.878 0.000 54.690  ? 60   TYR BBB HH   1 
ATOM   4219 N N    . TYR B 2 60  ? -22.773 -16.040 53.688 1.000 44.820  ? 61   TYR BBB N    1 
ATOM   4220 C CA   . TYR B 2 60  ? -22.060 -16.633 54.852 1.000 41.600  ? 61   TYR BBB CA   1 
ATOM   4221 C C    . TYR B 2 60  ? -22.667 -17.992 55.158 1.000 40.380  ? 61   TYR BBB C    1 
ATOM   4222 O O    . TYR B 2 60  ? -23.861 -18.187 54.969 1.000 44.390  ? 61   TYR BBB O    1 
ATOM   4223 C CB   . TYR B 2 60  ? -22.192 -15.740 56.075 1.000 38.940  ? 61   TYR BBB CB   1 
ATOM   4224 C CG   . TYR B 2 60  ? -22.014 -14.272 55.845 1.000 36.230  ? 61   TYR BBB CG   1 
ATOM   4225 C CD1  . TYR B 2 60  ? -23.063 -13.481 55.388 1.000 38.410  ? 61   TYR BBB CD1  1 
ATOM   4226 C CD2  . TYR B 2 60  ? -20.813 -13.660 56.141 1.000 35.050  ? 61   TYR BBB CD2  1 
ATOM   4227 C CE1  . TYR B 2 60  ? -22.912 -12.108 55.217 1.000 38.930  ? 61   TYR BBB CE1  1 
ATOM   4228 C CE2  . TYR B 2 60  ? -20.638 -12.293 55.937 1.000 41.650  ? 61   TYR BBB CE2  1 
ATOM   4229 C CZ   . TYR B 2 60  ? -21.697 -11.506 55.500 1.000 40.550  ? 61   TYR BBB CZ   1 
ATOM   4230 O OH   . TYR B 2 60  ? -21.510 -10.161 55.337 1.000 48.090  ? 61   TYR BBB OH   1 
ATOM   4231 H H    . TYR B 2 60  ? -23.782 -16.078 53.657 1.000 44.820  ? 61   TYR BBB H    1 
ATOM   4232 H HA   . TYR B 2 60  ? -21.107 -16.757 54.609 1.000 41.600  ? 61   TYR BBB HA   1 
ATOM   4233 H HB2  . TYR B 2 60  ? -23.079 -15.881 56.467 1.000 38.940  ? 61   TYR BBB HB2  1 
ATOM   4234 H HB3  . TYR B 2 60  ? -21.531 -16.026 56.740 1.000 38.940  ? 61   TYR BBB HB3  1 
ATOM   4235 H HD1  . TYR B 2 60  ? -23.902 -13.878 55.220 1.000 38.410  ? 61   TYR BBB HD1  1 
ATOM   4236 H HD2  . TYR B 2 60  ? -20.098 -14.169 56.486 1.000 35.050  ? 61   TYR BBB HD2  1 
ATOM   4237 H HE1  . TYR B 2 60  ? -23.634 -11.587 54.906 1.000 38.930  ? 61   TYR BBB HE1  1 
ATOM   4238 H HE2  . TYR B 2 60  ? -19.805 -11.896 56.133 1.000 41.650  ? 61   TYR BBB HE2  1 
ATOM   4239 H HH   . TYR B 2 60  ? -22.058 -9.726  55.834 0.000 48.090  ? 61   TYR BBB HH   1 
ATOM   4240 N N    . PRO B 2 61  ? -21.884 -19.011 55.546 1.000 44.620  ? 62   PRO BBB N    1 
ATOM   4241 C CA   . PRO B 2 61  ? -22.484 -20.279 55.979 1.000 47.240  ? 62   PRO BBB CA   1 
ATOM   4242 C C    . PRO B 2 61  ? -23.262 -20.039 57.282 1.000 45.590  ? 62   PRO BBB C    1 
ATOM   4243 O O    . PRO B 2 61  ? -22.826 -19.164 58.048 1.000 49.460  ? 62   PRO BBB O    1 
ATOM   4244 C CB   . PRO B 2 61  ? -21.301 -21.243 56.186 1.000 44.610  ? 62   PRO BBB CB   1 
ATOM   4245 C CG   . PRO B 2 61  ? -20.040 -20.379 56.121 1.000 45.960  ? 62   PRO BBB CG   1 
ATOM   4246 C CD   . PRO B 2 61  ? -20.414 -19.040 55.499 1.000 47.790  ? 62   PRO BBB CD   1 
ATOM   4247 H HA   . PRO B 2 61  ? -23.076 -20.622 55.263 1.000 47.240  ? 62   PRO BBB HA   1 
ATOM   4248 H HB2  . PRO B 2 61  ? -21.363 -21.695 57.053 1.000 44.610  ? 62   PRO BBB HB2  1 
ATOM   4249 H HB3  . PRO B 2 61  ? -21.282 -21.931 55.489 1.000 44.610  ? 62   PRO BBB HB3  1 
ATOM   4250 H HG2  . PRO B 2 61  ? -19.672 -20.231 57.017 1.000 45.960  ? 62   PRO BBB HG2  1 
ATOM   4251 H HG3  . PRO B 2 61  ? -19.349 -20.810 55.576 1.000 45.960  ? 62   PRO BBB HG3  1 
ATOM   4252 H HD2  . PRO B 2 61  ? -20.027 -18.298 56.009 1.000 47.790  ? 62   PRO BBB HD2  1 
ATOM   4253 H HD3  . PRO B 2 61  ? -20.086 -18.979 54.578 1.000 47.790  ? 62   PRO BBB HD3  1 
ATOM   4254 N N    . ASP B 2 62  ? -24.367 -20.759 57.493 1.000 45.010  ? 63   ASP BBB N    1 
ATOM   4255 C CA   . ASP B 2 62  ? -25.242 -20.629 58.703 1.000 50.050  ? 63   ASP BBB CA   1 
ATOM   4256 C C    . ASP B 2 62  ? -24.384 -20.669 59.974 1.000 48.670  ? 63   ASP BBB C    1 
ATOM   4257 O O    . ASP B 2 62  ? -24.582 -19.810 60.837 1.000 53.610  ? 63   ASP BBB O    1 
ATOM   4258 C CB   . ASP B 2 62  ? -26.335 -21.699 58.746 1.000 48.870  ? 63   ASP BBB CB   1 
ATOM   4259 C CG   . ASP B 2 62  ? -27.383 -21.528 57.651 1.000 55.260  ? 63   ASP BBB CG   1 
ATOM   4260 O OD1  . ASP B 2 62  ? -27.270 -20.581 56.872 1.000 65.830  ? 63   ASP BBB OD1  1 
ATOM   4261 O OD2  . ASP B 2 62  ? -28.307 -22.341 57.574 1.000 66.890  ? 63   ASP BBB OD2  1 
ATOM   4262 H H    . ASP B 2 62  ? -24.611 -21.429 56.778 1.000 45.010  ? 63   ASP BBB H    1 
ATOM   4263 H HA   . ASP B 2 62  ? -25.703 -19.758 58.664 1.000 50.050  ? 63   ASP BBB HA   1 
ATOM   4264 H HB2  . ASP B 2 62  ? -25.916 -22.576 58.629 1.000 48.870  ? 63   ASP BBB HB2  1 
ATOM   4265 H HB3  . ASP B 2 62  ? -26.790 -21.644 59.611 1.000 48.870  ? 63   ASP BBB HB3  1 
ATOM   4266 N N    . SER B 2 63  ? -23.391 -21.554 60.033 1.000 49.380  ? 64   SER BBB N    1 
ATOM   4267 C CA   . SER B 2 63  ? -22.448 -21.694 61.175 1.000 51.900  ? 64   SER BBB CA   1 
ATOM   4268 C C    . SER B 2 63  ? -21.933 -20.333 61.673 1.000 54.390  ? 64   SER BBB C    1 
ATOM   4269 O O    . SER B 2 63  ? -21.625 -20.219 62.888 1.000 53.830  ? 64   SER BBB O    1 
ATOM   4270 C CB   . SER B 2 63  ? -21.282 -22.640 60.863 1.000 54.870  ? 64   SER BBB CB   1 
ATOM   4271 O OG   . SER B 2 63  ? -21.100 -22.893 59.476 1.000 55.110  ? 64   SER BBB OG   1 
ATOM   4272 H H    . SER B 2 63  ? -23.290 -22.163 59.234 1.000 49.380  ? 64   SER BBB H    1 
ATOM   4273 H HA   . SER B 2 63  ? -22.939 -22.116 61.930 1.000 51.900  ? 64   SER BBB HA   1 
ATOM   4274 H HB2  . SER B 2 63  ? -20.447 -22.253 61.210 1.000 54.870  ? 64   SER BBB HB2  1 
ATOM   4275 H HB3  . SER B 2 63  ? -21.436 -23.504 61.309 1.000 54.870  ? 64   SER BBB HB3  1 
ATOM   4276 H HG   . SER B 2 63  ? -20.444 -23.419 59.382 0.000 55.110  ? 64   SER BBB HG   1 
ATOM   4277 N N    . VAL B 2 64  ? -21.791 -19.330 60.810 1.000 50.480  ? 65   VAL BBB N    1 
ATOM   4278 C CA   . VAL B 2 64  ? -21.066 -18.074 61.192 1.000 50.010  ? 65   VAL BBB CA   1 
ATOM   4279 C C    . VAL B 2 64  ? -21.947 -16.824 60.986 1.000 48.420  ? 65   VAL BBB C    1 
ATOM   4280 O O    . VAL B 2 64  ? -21.442 -15.693 61.209 1.000 51.940  ? 65   VAL BBB O    1 
ATOM   4281 C CB   . VAL B 2 64  ? -19.744 -17.981 60.404 1.000 58.890  ? 65   VAL BBB CB   1 
ATOM   4282 C CG1  . VAL B 2 64  ? -18.888 -19.230 60.596 1.000 55.240  ? 65   VAL BBB CG1  1 
ATOM   4283 C CG2  . VAL B 2 64  ? -19.976 -17.695 58.915 1.000 61.720  ? 65   VAL BBB CG2  1 
ATOM   4284 H H    . VAL B 2 64  ? -22.177 -19.412 59.880 1.000 50.480  ? 65   VAL BBB H    1 
ATOM   4285 H HA   . VAL B 2 64  ? -20.849 -18.120 62.140 1.000 50.010  ? 65   VAL BBB HA   1 
ATOM   4286 H HB   . VAL B 2 64  ? -19.234 -17.219 60.776 1.000 58.890  ? 65   VAL BBB HB   1 
ATOM   4287 H HG11 . VAL B 2 64  ? -18.677 -19.337 61.540 1.000 55.240  ? 65   VAL BBB HG11 1 
ATOM   4288 H HG12 . VAL B 2 64  ? -18.064 -19.140 60.087 1.000 55.240  ? 65   VAL BBB HG12 1 
ATOM   4289 H HG13 . VAL B 2 64  ? -19.378 -20.011 60.284 1.000 55.240  ? 65   VAL BBB HG13 1 
ATOM   4290 H HG21 . VAL B 2 64  ? -20.510 -18.409 58.526 1.000 61.720  ? 65   VAL BBB HG21 1 
ATOM   4291 H HG22 . VAL B 2 64  ? -19.119 -17.644 58.457 1.000 61.720  ? 65   VAL BBB HG22 1 
ATOM   4292 H HG23 . VAL B 2 64  ? -20.447 -16.849 58.816 1.000 61.720  ? 65   VAL BBB HG23 1 
ATOM   4293 N N    . GLU B 2 65  ? -23.217 -16.993 60.592 1.000 47.070  ? 66   GLU BBB N    1 
ATOM   4294 C CA   . GLU B 2 65  ? -24.192 -15.879 60.451 1.000 44.440  ? 66   GLU BBB CA   1 
ATOM   4295 C C    . GLU B 2 65  ? -24.220 -15.106 61.773 1.000 47.450  ? 66   GLU BBB C    1 
ATOM   4296 O O    . GLU B 2 65  ? -24.486 -15.739 62.811 1.000 48.310  ? 66   GLU BBB O    1 
ATOM   4297 C CB   . GLU B 2 65  ? -25.570 -16.431 60.101 1.000 42.570  ? 66   GLU BBB CB   1 
ATOM   4298 C CG   . GLU B 2 65  ? -25.661 -16.987 58.708 1.000 44.740  ? 66   GLU BBB CG   1 
ATOM   4299 C CD   . GLU B 2 65  ? -25.830 -15.930 57.627 1.000 44.020  ? 66   GLU BBB CD   1 
ATOM   4300 O OE1  . GLU B 2 65  ? -25.465 -14.743 57.848 1.000 41.170  ? 66   GLU BBB OE1  1 
ATOM   4301 O OE2  . GLU B 2 65  ? -26.337 -16.298 56.572 1.000 48.440  ? 66   GLU BBB OE2  1 
ATOM   4302 H H    . GLU B 2 65  ? -23.513 -17.936 60.383 1.000 47.070  ? 66   GLU BBB H    1 
ATOM   4303 H HA   . GLU B 2 65  ? -23.884 -15.283 59.730 1.000 44.440  ? 66   GLU BBB HA   1 
ATOM   4304 H HB2  . GLU B 2 65  ? -25.793 -17.141 60.739 1.000 42.570  ? 66   GLU BBB HB2  1 
ATOM   4305 H HB3  . GLU B 2 65  ? -26.228 -15.711 60.197 1.000 42.570  ? 66   GLU BBB HB3  1 
ATOM   4306 H HG2  . GLU B 2 65  ? -24.849 -17.503 58.518 1.000 44.740  ? 66   GLU BBB HG2  1 
ATOM   4307 H HG3  . GLU B 2 65  ? -26.420 -17.607 58.662 1.000 44.740  ? 66   GLU BBB HG3  1 
ATOM   4308 N N    . GLY B 2 66  ? -23.912 -13.816 61.738 1.000 43.000  ? 67   GLY BBB N    1 
ATOM   4309 C CA   . GLY B 2 66  ? -23.953 -12.961 62.931 1.000 45.580  ? 67   GLY BBB CA   1 
ATOM   4310 C C    . GLY B 2 66  ? -22.563 -12.683 63.460 1.000 46.310  ? 67   GLY BBB C    1 
ATOM   4311 O O    . GLY B 2 66  ? -22.399 -11.672 64.189 1.000 50.340  ? 67   GLY BBB O    1 
ATOM   4312 H H    . GLY B 2 66  ? -23.640 -13.413 60.853 1.000 43.000  ? 67   GLY BBB H    1 
ATOM   4313 H HA2  . GLY B 2 66  ? -24.397 -12.107 62.701 1.000 45.580  ? 67   GLY BBB HA2  1 
ATOM   4314 H HA3  . GLY B 2 66  ? -24.491 -13.409 63.631 1.000 45.580  ? 67   GLY BBB HA3  1 
ATOM   4315 N N    . ARG B 2 67  ? -21.574 -13.489 63.085 1.000 48.550  ? 68   ARG BBB N    1 
ATOM   4316 C CA   . ARG B 2 67  ? -20.190 -13.296 63.595 1.000 58.490  ? 68   ARG BBB CA   1 
ATOM   4317 C C    . ARG B 2 67  ? -19.252 -12.631 62.568 1.000 55.060  ? 68   ARG BBB C    1 
ATOM   4318 O O    . ARG B 2 67  ? -18.160 -12.144 62.976 1.000 53.680  ? 68   ARG BBB O    1 
ATOM   4319 C CB   . ARG B 2 67  ? -19.667 -14.653 64.061 1.000 65.080  ? 68   ARG BBB CB   1 
ATOM   4320 C CG   . ARG B 2 67  ? -19.908 -14.889 65.544 1.000 72.650  ? 68   ARG BBB CG   1 
ATOM   4321 C CD   . ARG B 2 67  ? -18.984 -15.981 66.013 1.000 68.850  ? 68   ARG BBB CD   1 
ATOM   4322 N NE   . ARG B 2 67  ? -19.504 -17.192 65.413 1.000 69.010  ? 68   ARG BBB NE   1 
ATOM   4323 C CZ   . ARG B 2 67  ? -18.773 -18.150 64.883 1.000 65.230  ? 68   ARG BBB CZ   1 
ATOM   4324 N NH1  . ARG B 2 67  ? -17.458 -18.038 64.846 1.000 66.840  ? 68   ARG BBB NH1  1 
ATOM   4325 N NH2  . ARG B 2 67  ? -19.370 -19.207 64.364 1.000 65.320  ? 68   ARG BBB NH2  1 
ATOM   4326 H H    . ARG B 2 67  ? -21.761 -14.246 62.443 1.000 48.550  ? 68   ARG BBB H    1 
ATOM   4327 H HA   . ARG B 2 67  ? -20.226 -12.700 64.378 1.000 58.490  ? 68   ARG BBB HA   1 
ATOM   4328 H HB2  . ARG B 2 67  ? -20.111 -15.354 63.539 1.000 65.080  ? 68   ARG BBB HB2  1 
ATOM   4329 H HB3  . ARG B 2 67  ? -18.707 -14.699 63.872 1.000 65.080  ? 68   ARG BBB HB3  1 
ATOM   4330 H HG2  . ARG B 2 67  ? -19.743 -14.056 66.035 1.000 72.650  ? 68   ARG BBB HG2  1 
ATOM   4331 H HG3  . ARG B 2 67  ? -20.846 -15.141 65.683 1.000 72.650  ? 68   ARG BBB HG3  1 
ATOM   4332 H HD2  . ARG B 2 67  ? -18.069 -15.775 65.726 1.000 68.850  ? 68   ARG BBB HD2  1 
ATOM   4333 H HD3  . ARG B 2 67  ? -18.988 -16.008 66.994 1.000 68.850  ? 68   ARG BBB HD3  1 
ATOM   4334 H HE   . ARG B 2 67  ? -20.369 -17.301 65.399 1.000 69.010  ? 68   ARG BBB HE   1 
ATOM   4335 H HH11 . ARG B 2 67  ? -17.070 -17.322 65.176 1.000 66.840  ? 68   ARG BBB HH11 1 
ATOM   4336 H HH12 . ARG B 2 67  ? -16.974 -18.680 64.491 1.000 66.840  ? 68   ARG BBB HH12 1 
ATOM   4337 H HH21 . ARG B 2 67  ? -20.249 -19.264 64.376 1.000 65.320  ? 68   ARG BBB HH21 1 
ATOM   4338 H HH22 . ARG B 2 67  ? -18.888 -19.852 64.008 1.000 65.320  ? 68   ARG BBB HH22 1 
ATOM   4339 N N    . PHE B 2 68  ? -19.633 -12.616 61.290 1.000 49.720  ? 69   PHE BBB N    1 
ATOM   4340 C CA   . PHE B 2 68  ? -18.826 -12.045 60.177 1.000 50.180  ? 69   PHE BBB CA   1 
ATOM   4341 C C    . PHE B 2 68  ? -19.701 -11.114 59.342 1.000 44.130  ? 69   PHE BBB C    1 
ATOM   4342 O O    . PHE B 2 68  ? -20.821 -11.517 58.993 1.000 43.990  ? 69   PHE BBB O    1 
ATOM   4343 C CB   . PHE B 2 68  ? -18.283 -13.154 59.263 1.000 55.020  ? 69   PHE BBB CB   1 
ATOM   4344 C CG   . PHE B 2 68  ? -17.295 -14.080 59.928 1.000 57.490  ? 69   PHE BBB CG   1 
ATOM   4345 C CD1  . PHE B 2 68  ? -16.070 -13.622 60.377 1.000 55.060  ? 69   PHE BBB CD1  1 
ATOM   4346 C CD2  . PHE B 2 68  ? -17.597 -15.412 60.124 1.000 61.220  ? 69   PHE BBB CD2  1 
ATOM   4347 C CE1  . PHE B 2 68  ? -15.164 -14.472 60.989 1.000 52.260  ? 69   PHE BBB CE1  1 
ATOM   4348 C CE2  . PHE B 2 68  ? -16.699 -16.254 60.764 1.000 57.580  ? 69   PHE BBB CE2  1 
ATOM   4349 C CZ   . PHE B 2 68  ? -15.485 -15.779 61.196 1.000 47.770  ? 69   PHE BBB CZ   1 
ATOM   4350 H H    . PHE B 2 68  ? -20.534 -13.025 61.086 1.000 49.720  ? 69   PHE BBB H    1 
ATOM   4351 H HA   . PHE B 2 68  ? -18.084 -11.515 60.564 1.000 50.180  ? 69   PHE BBB HA   1 
ATOM   4352 H HB2  . PHE B 2 68  ? -19.040 -13.679 58.930 1.000 55.020  ? 69   PHE BBB HB2  1 
ATOM   4353 H HB3  . PHE B 2 68  ? -17.856 -12.735 58.487 1.000 55.020  ? 69   PHE BBB HB3  1 
ATOM   4354 H HD1  . PHE B 2 68  ? -15.844 -12.712 60.267 1.000 55.060  ? 69   PHE BBB HD1  1 
ATOM   4355 H HD2  . PHE B 2 68  ? -18.423 -15.752 59.819 1.000 61.220  ? 69   PHE BBB HD2  1 
ATOM   4356 H HE1  . PHE B 2 68  ? -14.334 -14.136 61.287 1.000 52.260  ? 69   PHE BBB HE1  1 
ATOM   4357 H HE2  . PHE B 2 68  ? -16.927 -17.159 60.905 1.000 57.580  ? 69   PHE BBB HE2  1 
ATOM   4358 H HZ   . PHE B 2 68  ? -14.866 -16.356 61.613 1.000 47.770  ? 69   PHE BBB HZ   1 
ATOM   4359 N N    . THR B 2 69  ? -19.211 -9.928  59.020 1.000 41.480  ? 70   THR BBB N    1 
ATOM   4360 C CA   . THR B 2 69  ? -19.785 -9.088  57.946 1.000 45.910  ? 70   THR BBB CA   1 
ATOM   4361 C C    . THR B 2 69  ? -18.674 -8.795  56.920 1.000 46.490  ? 70   THR BBB C    1 
ATOM   4362 O O    . THR B 2 69  ? -17.706 -8.053  57.266 1.000 37.730  ? 70   THR BBB O    1 
ATOM   4363 C CB   . THR B 2 69  ? -20.436 -7.821  58.523 1.000 52.840  ? 70   THR BBB CB   1 
ATOM   4364 O OG1  . THR B 2 69  ? -21.461 -8.184  59.449 1.000 47.500  ? 70   THR BBB OG1  1 
ATOM   4365 C CG2  . THR B 2 69  ? -21.036 -6.927  57.457 1.000 53.910  ? 70   THR BBB CG2  1 
ATOM   4366 H H    . THR B 2 69  ? -18.411 -9.590  59.535 1.000 41.480  ? 70   THR BBB H    1 
ATOM   4367 H HA   . THR B 2 69  ? -20.503 -9.601  57.508 1.000 45.910  ? 70   THR BBB HA   1 
ATOM   4368 H HB   . THR B 2 69  ? -19.745 -7.313  59.012 1.000 52.840  ? 70   THR BBB HB   1 
ATOM   4369 H HG1  . THR B 2 69  ? -21.819 -7.484  59.766 0.000 47.500  ? 70   THR BBB HG1  1 
ATOM   4370 H HG21 . THR B 2 69  ? -20.339 -6.644  56.838 1.000 53.910  ? 70   THR BBB HG21 1 
ATOM   4371 H HG22 . THR B 2 69  ? -21.433 -6.142  57.875 1.000 53.910  ? 70   THR BBB HG22 1 
ATOM   4372 H HG23 . THR B 2 69  ? -21.723 -7.416  56.970 1.000 53.910  ? 70   THR BBB HG23 1 
ATOM   4373 N N    . ILE B 2 70  ? -18.835 -9.319  55.701 1.000 41.280  ? 71   ILE BBB N    1 
ATOM   4374 C CA   . ILE B 2 70  ? -17.989 -8.931  54.533 1.000 44.130  ? 71   ILE BBB CA   1 
ATOM   4375 C C    . ILE B 2 70  ? -18.606 -7.689  53.878 1.000 44.420  ? 71   ILE BBB C    1 
ATOM   4376 O O    . ILE B 2 70  ? -19.849 -7.645  53.738 1.000 46.570  ? 71   ILE BBB O    1 
ATOM   4377 C CB   . ILE B 2 70  ? -17.826 -10.087 53.525 1.000 39.160  ? 71   ILE BBB CB   1 
ATOM   4378 C CG1  . ILE B 2 70  ? -16.810 -9.718  52.444 1.000 39.250  ? 71   ILE BBB CG1  1 
ATOM   4379 C CG2  . ILE B 2 70  ? -19.152 -10.531 52.918 1.000 37.740  ? 71   ILE BBB CG2  1 
ATOM   4380 C CD1  . ILE B 2 70  ? -16.435 -10.865 51.545 1.000 38.130  ? 71   ILE BBB CD1  1 
ATOM   4381 H H    . ILE B 2 70  ? -19.564 -10.007 55.574 1.000 41.280  ? 71   ILE BBB H    1 
ATOM   4382 H HA   . ILE B 2 70  ? -17.100 -8.703  54.860 1.000 44.130  ? 71   ILE BBB HA   1 
ATOM   4383 H HB   . ILE B 2 70  ? -17.466 -10.863 54.021 1.000 39.160  ? 71   ILE BBB HB   1 
ATOM   4384 H HG12 . ILE B 2 70  ? -17.183 -8.995  51.895 1.000 39.250  ? 71   ILE BBB HG12 1 
ATOM   4385 H HG13 . ILE B 2 70  ? -15.998 -9.378  52.878 1.000 39.250  ? 71   ILE BBB HG13 1 
ATOM   4386 H HG21 . ILE B 2 70  ? -19.748 -10.838 53.623 1.000 37.740  ? 71   ILE BBB HG21 1 
ATOM   4387 H HG22 . ILE B 2 70  ? -18.998 -11.261 52.293 1.000 37.740  ? 71   ILE BBB HG22 1 
ATOM   4388 H HG23 . ILE B 2 70  ? -19.563 -9.785  52.448 1.000 37.740  ? 71   ILE BBB HG23 1 
ATOM   4389 H HD11 . ILE B 2 70  ? -16.043 -11.580 52.076 1.000 38.130  ? 71   ILE BBB HD11 1 
ATOM   4390 H HD12 . ILE B 2 70  ? -15.789 -10.563 50.884 1.000 38.130  ? 71   ILE BBB HD12 1 
ATOM   4391 H HD13 . ILE B 2 70  ? -17.229 -11.197 51.092 1.000 38.130  ? 71   ILE BBB HD13 1 
ATOM   4392 N N    . SER B 2 71  ? -17.756 -6.739  53.498 1.000 39.570  ? 72   SER BBB N    1 
ATOM   4393 C CA   . SER B 2 71  ? -18.116 -5.480  52.796 1.000 45.020  ? 72   SER BBB CA   1 
ATOM   4394 C C    . SER B 2 71  ? -16.988 -5.088  51.821 1.000 47.950  ? 72   SER BBB C    1 
ATOM   4395 O O    . SER B 2 71  ? -15.937 -5.767  51.785 1.000 44.990  ? 72   SER BBB O    1 
ATOM   4396 C CB   . SER B 2 71  ? -18.370 -4.408  53.807 1.000 46.450  ? 72   SER BBB CB   1 
ATOM   4397 O OG   . SER B 2 71  ? -17.167 -4.042  54.493 1.000 44.810  ? 72   SER BBB OG   1 
ATOM   4398 H H    . SER B 2 71  ? -16.787 -6.919  53.721 1.000 39.570  ? 72   SER BBB H    1 
ATOM   4399 H HA   . SER B 2 71  ? -18.942 -5.647  52.267 1.000 45.020  ? 72   SER BBB HA   1 
ATOM   4400 H HB2  . SER B 2 71  ? -18.738 -3.615  53.355 1.000 46.450  ? 72   SER BBB HB2  1 
ATOM   4401 H HB3  . SER B 2 71  ? -19.030 -4.729  54.462 1.000 46.450  ? 72   SER BBB HB3  1 
ATOM   4402 H HG   . SER B 2 71  ? -17.351 -3.436  55.054 0.000 44.810  ? 72   SER BBB HG   1 
ATOM   4403 N N    . ARG B 2 72  ? -17.167 -4.048  51.020 1.000 42.290  ? 73   ARG BBB N    1 
ATOM   4404 C CA   . ARG B 2 72  ? -16.091 -3.646  50.084 1.000 46.600  ? 73   ARG BBB CA   1 
ATOM   4405 C C    . ARG B 2 72  ? -16.257 -2.172  49.754 1.000 49.650  ? 73   ARG BBB C    1 
ATOM   4406 O O    . ARG B 2 72  ? -17.387 -1.696  49.889 1.000 47.600  ? 73   ARG BBB O    1 
ATOM   4407 C CB   . ARG B 2 72  ? -16.088 -4.504  48.813 1.000 42.590  ? 73   ARG BBB CB   1 
ATOM   4408 C CG   . ARG B 2 72  ? -17.266 -4.312  47.857 1.000 39.600  ? 73   ARG BBB CG   1 
ATOM   4409 C CD   . ARG B 2 72  ? -16.751 -4.529  46.455 1.000 45.340  ? 73   ARG BBB CD   1 
ATOM   4410 N NE   . ARG B 2 72  ? -16.886 -5.893  45.992 1.000 43.390  ? 73   ARG BBB NE   1 
ATOM   4411 C CZ   . ARG B 2 72  ? -16.015 -6.586  45.241 1.000 37.450  ? 73   ARG BBB CZ   1 
ATOM   4412 N NH1  . ARG B 2 72  ? -14.847 -6.112  44.817 1.000 35.560  ? 73   ARG BBB NH1  1 
ATOM   4413 N NH2  . ARG B 2 72  ? -16.368 -7.805  44.891 1.000 37.780  ? 73   ARG BBB NH2  1 
ATOM   4414 H H    . ARG B 2 72  ? -18.028 -3.521  51.036 1.000 42.290  ? 73   ARG BBB H    1 
ATOM   4415 H HA   . ARG B 2 72  ? -15.223 -3.780  50.530 1.000 46.600  ? 73   ARG BBB HA   1 
ATOM   4416 H HB2  . ARG B 2 72  ? -15.267 -4.315  48.312 1.000 42.590  ? 73   ARG BBB HB2  1 
ATOM   4417 H HB3  . ARG B 2 72  ? -16.071 -5.448  49.074 1.000 42.590  ? 73   ARG BBB HB3  1 
ATOM   4418 H HG2  . ARG B 2 72  ? -17.974 -4.953  48.083 1.000 39.600  ? 73   ARG BBB HG2  1 
ATOM   4419 H HG3  . ARG B 2 72  ? -17.630 -3.408  47.970 1.000 39.600  ? 73   ARG BBB HG3  1 
ATOM   4420 H HD2  . ARG B 2 72  ? -17.237 -3.941  45.838 1.000 45.340  ? 73   ARG BBB HD2  1 
ATOM   4421 H HD3  . ARG B 2 72  ? -15.803 -4.279  46.417 1.000 45.340  ? 73   ARG BBB HD3  1 
ATOM   4422 H HE   . ARG B 2 72  ? -17.607 -6.330  46.216 1.000 43.390  ? 73   ARG BBB HE   1 
ATOM   4423 H HH11 . ARG B 2 72  ? -14.604 -5.294  45.028 1.000 35.560  ? 73   ARG BBB HH11 1 
ATOM   4424 H HH12 . ARG B 2 72  ? -14.321 -6.618  44.327 1.000 35.560  ? 73   ARG BBB HH12 1 
ATOM   4425 H HH21 . ARG B 2 72  ? -17.145 -8.128  45.151 1.000 37.780  ? 73   ARG BBB HH21 1 
ATOM   4426 H HH22 . ARG B 2 72  ? -15.826 -8.294  44.398 1.000 37.780  ? 73   ARG BBB HH22 1 
ATOM   4427 N N    . ASP B 2 73  ? -15.169 -1.523  49.323 1.000 49.320  ? 74   ASP BBB N    1 
ATOM   4428 C CA   . ASP B 2 73  ? -15.139 -0.103  48.895 1.000 51.340  ? 74   ASP BBB CA   1 
ATOM   4429 C C    . ASP B 2 73  ? -14.406 -0.079  47.553 1.000 49.430  ? 74   ASP BBB C    1 
ATOM   4430 O O    . ASP B 2 73  ? -13.146 -0.168  47.563 1.000 49.430  ? 74   ASP BBB O    1 
ATOM   4431 C CB   . ASP B 2 73  ? -14.514 0.749   50.001 1.000 53.510  ? 74   ASP BBB CB   1 
ATOM   4432 C CG   . ASP B 2 73  ? -14.137 2.164   49.590 1.000 62.840  ? 74   ASP BBB CG   1 
ATOM   4433 O OD1  . ASP B 2 73  ? -14.150 2.468   48.375 1.000 64.620  ? 74   ASP BBB OD1  1 
ATOM   4434 O OD2  . ASP B 2 73  ? -13.820 2.955   50.491 1.000 63.120  ? 74   ASP BBB OD2  1 
ATOM   4435 H H    . ASP B 2 73  ? -14.316 -2.063  49.297 1.000 49.320  ? 74   ASP BBB H    1 
ATOM   4436 H HA   . ASP B 2 73  ? -16.067 0.209   48.783 1.000 51.340  ? 74   ASP BBB HA   1 
ATOM   4437 H HB2  . ASP B 2 73  ? -15.158 0.826   50.735 1.000 53.510  ? 74   ASP BBB HB2  1 
ATOM   4438 H HB3  . ASP B 2 73  ? -13.693 0.311   50.304 1.000 53.510  ? 74   ASP BBB HB3  1 
ATOM   4439 N N    . ASN B 2 74  ? -15.141 -0.007  46.438 1.000 49.590  ? 75   ASN BBB N    1 
ATOM   4440 C CA   . ASN B 2 74  ? -14.539 -0.187  45.083 1.000 54.260  ? 75   ASN BBB CA   1 
ATOM   4441 C C    . ASN B 2 74  ? -13.639 1.011   44.696 1.000 53.210  ? 75   ASN BBB C    1 
ATOM   4442 O O    . ASN B 2 74  ? -12.617 0.796   43.989 1.000 48.640  ? 75   ASN BBB O    1 
ATOM   4443 C CB   . ASN B 2 74  ? -15.616 -0.500  44.051 1.000 51.600  ? 75   ASN BBB CB   1 
ATOM   4444 C CG   . ASN B 2 74  ? -16.128 -1.911  44.182 1.000 46.450  ? 75   ASN BBB CG   1 
ATOM   4445 O OD1  . ASN B 2 74  ? -15.432 -2.774  44.701 1.000 40.980  ? 75   ASN BBB OD1  1 
ATOM   4446 N ND2  . ASN B 2 74  ? -17.323 -2.146  43.677 1.000 42.140  ? 75   ASN BBB ND2  1 
ATOM   4447 H H    . ASN B 2 74  ? -16.131 0.174   46.517 1.000 49.590  ? 75   ASN BBB H    1 
ATOM   4448 H HA   . ASN B 2 74  ? -13.973 -0.995  45.097 1.000 54.260  ? 75   ASN BBB HA   1 
ATOM   4449 H HB2  . ASN B 2 74  ? -16.357 0.130   44.164 1.000 51.600  ? 75   ASN BBB HB2  1 
ATOM   4450 H HB3  . ASN B 2 74  ? -15.245 -0.367  43.155 1.000 51.600  ? 75   ASN BBB HB3  1 
ATOM   4451 H HD21 . ASN B 2 74  ? -17.672 -2.957  43.726 0.000 42.140  ? 75   ASN BBB HD21 1 
ATOM   4452 H HD22 . ASN B 2 74  ? -17.775 -1.493  43.289 0.000 42.140  ? 75   ASN BBB HD22 1 
ATOM   4453 N N    . ALA B 2 75  ? -13.945 2.212   45.184 1.000 53.130  ? 76   ALA BBB N    1 
ATOM   4454 C CA   . ALA B 2 75  ? -13.104 3.421   44.998 1.000 59.910  ? 76   ALA BBB CA   1 
ATOM   4455 C C    . ALA B 2 75  ? -11.689 3.176   45.539 1.000 61.620  ? 76   ALA BBB C    1 
ATOM   4456 O O    . ALA B 2 75  ? -10.759 3.735   44.979 1.000 72.120  ? 76   ALA BBB O    1 
ATOM   4457 C CB   . ALA B 2 75  ? -13.740 4.616   45.668 1.000 57.790  ? 76   ALA BBB CB   1 
ATOM   4458 H H    . ALA B 2 75  ? -14.804 2.286   45.709 1.000 53.130  ? 76   ALA BBB H    1 
ATOM   4459 H HA   . ALA B 2 75  ? -13.036 3.610   44.033 1.000 59.910  ? 76   ALA BBB HA   1 
ATOM   4460 H HB1  . ALA B 2 75  ? -13.180 5.397   45.538 1.000 57.790  ? 76   ALA BBB HB1  1 
ATOM   4461 H HB2  . ALA B 2 75  ? -14.614 4.778   45.280 1.000 57.790  ? 76   ALA BBB HB2  1 
ATOM   4462 H HB3  . ALA B 2 75  ? -13.836 4.442   46.620 1.000 57.790  ? 76   ALA BBB HB3  1 
ATOM   4463 N N    . LYS B 2 76  ? -11.523 2.373   46.587 1.000 58.210  ? 77   LYS BBB N    1 
ATOM   4464 C CA   . LYS B 2 76  ? -10.202 2.157   47.225 1.000 55.460  ? 77   LYS BBB CA   1 
ATOM   4465 C C    . LYS B 2 76  ? -9.639  0.794   46.852 1.000 55.440  ? 77   LYS BBB C    1 
ATOM   4466 O O    . LYS B 2 76  ? -8.512  0.516   47.272 1.000 46.570  ? 77   LYS BBB O    1 
ATOM   4467 C CB   . LYS B 2 76  ? -10.345 2.220   48.742 1.000 62.930  ? 77   LYS BBB CB   1 
ATOM   4468 C CG   . LYS B 2 76  ? -10.706 3.591   49.269 1.000 66.970  ? 77   LYS BBB CG   1 
ATOM   4469 C CD   . LYS B 2 76  ? -10.437 3.726   50.733 1.000 74.640  ? 77   LYS BBB CD   1 
ATOM   4470 C CE   . LYS B 2 76  ? -11.104 4.957   51.301 1.000 84.970  ? 77   LYS BBB CE   1 
ATOM   4471 N NZ   . LYS B 2 76  ? -10.352 5.505   52.453 1.000 98.910  ? 77   LYS BBB NZ   1 
ATOM   4472 H H    . LYS B 2 76  ? -12.332 1.895   46.957 1.000 58.210  ? 77   LYS BBB H    1 
ATOM   4473 H HA   . LYS B 2 76  ? -9.580  2.846   46.895 1.000 55.460  ? 77   LYS BBB HA   1 
ATOM   4474 H HB2  . LYS B 2 76  ? -11.030 1.575   49.018 1.000 62.930  ? 77   LYS BBB HB2  1 
ATOM   4475 H HB3  . LYS B 2 76  ? -9.502  1.928   49.147 1.000 62.930  ? 77   LYS BBB HB3  1 
ATOM   4476 H HG2  . LYS B 2 76  ? -10.183 4.262   48.780 1.000 66.970  ? 77   LYS BBB HG2  1 
ATOM   4477 H HG3  . LYS B 2 76  ? -11.659 3.751   49.098 1.000 66.970  ? 77   LYS BBB HG3  1 
ATOM   4478 H HD2  . LYS B 2 76  ? -10.767 2.926   51.194 1.000 74.640  ? 77   LYS BBB HD2  1 
ATOM   4479 H HD3  . LYS B 2 76  ? -9.468  3.776   50.877 1.000 74.640  ? 77   LYS BBB HD3  1 
ATOM   4480 H HE2  . LYS B 2 76  ? -11.169 5.642   50.609 1.000 84.970  ? 77   LYS BBB HE2  1 
ATOM   4481 H HE3  . LYS B 2 76  ? -12.010 4.735   51.589 1.000 84.970  ? 77   LYS BBB HE3  1 
ATOM   4482 H HZ1  . LYS B 2 76  ? -10.298 4.881   53.109 1.000 98.910  ? 77   LYS BBB HZ1  1 
ATOM   4483 H HZ2  . LYS B 2 76  ? -10.773 6.243   52.771 1.000 98.910  ? 77   LYS BBB HZ2  1 
ATOM   4484 H HZ3  . LYS B 2 76  ? -9.514  5.732   52.192 1.000 98.910  ? 77   LYS BBB HZ3  1 
ATOM   4485 N N    . ARG B 2 77  ? -10.423 -0.031  46.149 1.000 58.530  ? 78   ARG BBB N    1 
ATOM   4486 C CA   . ARG B 2 77  ? -10.051 -1.416  45.739 1.000 57.350  ? 78   ARG BBB CA   1 
ATOM   4487 C C    . ARG B 2 77  ? -9.698  -2.224  46.990 1.000 55.410  ? 78   ARG BBB C    1 
ATOM   4488 O O    . ARG B 2 77  ? -8.687  -2.954  46.978 1.000 58.610  ? 78   ARG BBB O    1 
ATOM   4489 C CB   . ARG B 2 77  ? -8.947  -1.356  44.683 1.000 61.170  ? 78   ARG BBB CB   1 
ATOM   4490 C CG   . ARG B 2 77  ? -9.474  -0.881  43.335 1.000 77.200  ? 78   ARG BBB CG   1 
ATOM   4491 C CD   . ARG B 2 77  ? -8.577  0.085   42.603 1.000 80.210  ? 78   ARG BBB CD   1 
ATOM   4492 N NE   . ARG B 2 77  ? -7.292  -0.535  42.338 1.000 83.930  ? 78   ARG BBB NE   1 
ATOM   4493 C CZ   . ARG B 2 77  ? -6.135  -0.146  42.868 1.000 82.870  ? 78   ARG BBB CZ   1 
ATOM   4494 N NH1  . ARG B 2 77  ? -6.078  0.902   43.681 1.000 83.260  ? 78   ARG BBB NH1  1 
ATOM   4495 N NH2  . ARG B 2 77  ? -5.029  -0.806  42.562 1.000 86.800  ? 78   ARG BBB NH2  1 
ATOM   4496 H H    . ARG B 2 77  ? -11.328 0.333   45.888 1.000 58.530  ? 78   ARG BBB H    1 
ATOM   4497 H HA   . ARG B 2 77  ? -10.828 -1.831  45.298 1.000 57.350  ? 78   ARG BBB HA   1 
ATOM   4498 H HB2  . ARG B 2 77  ? -8.246  -0.749  44.999 1.000 61.170  ? 78   ARG BBB HB2  1 
ATOM   4499 H HB3  . ARG B 2 77  ? -8.554  -2.249  44.592 1.000 61.170  ? 78   ARG BBB HB3  1 
ATOM   4500 H HG2  . ARG B 2 77  ? -9.613  -1.656  42.750 1.000 77.200  ? 78   ARG BBB HG2  1 
ATOM   4501 H HG3  . ARG B 2 77  ? -10.341 -0.440  43.464 1.000 77.200  ? 78   ARG BBB HG3  1 
ATOM   4502 H HD2  . ARG B 2 77  ? -9.008  0.352   41.763 1.000 80.210  ? 78   ARG BBB HD2  1 
ATOM   4503 H HD3  . ARG B 2 77  ? -8.461  0.893   43.147 1.000 80.210  ? 78   ARG BBB HD3  1 
ATOM   4504 H HE   . ARG B 2 77  ? -7.272  -1.214  41.791 1.000 83.930  ? 78   ARG BBB HE   1 
ATOM   4505 H HH11 . ARG B 2 77  ? -6.811  1.347   43.874 1.000 83.260  ? 78   ARG BBB HH11 1 
ATOM   4506 H HH12 . ARG B 2 77  ? -5.307  1.148   44.024 1.000 83.260  ? 78   ARG BBB HH12 1 
ATOM   4507 H HH21 . ARG B 2 77  ? -5.067  -1.494  42.013 1.000 86.800  ? 78   ARG BBB HH21 1 
ATOM   4508 H HH22 . ARG B 2 77  ? -4.259  -0.555  42.908 1.000 86.800  ? 78   ARG BBB HH22 1 
ATOM   4509 N N    . MET B 2 78  ? -10.571 -2.124  47.992 1.000 49.780  ? 79   MET BBB N    1 
ATOM   4510 C CA   . MET B 2 78  ? -10.481 -2.800  49.307 1.000 48.720  ? 79   MET BBB CA   1 
ATOM   4511 C C    . MET B 2 78  ? -11.669 -3.729  49.483 1.000 45.360  ? 79   MET BBB C    1 
ATOM   4512 O O    . MET B 2 78  ? -12.754 -3.440  48.977 1.000 42.010  ? 79   MET BBB O    1 
ATOM   4513 C CB   . MET B 2 78  ? -10.526 -1.787  50.453 1.000 51.280  ? 79   MET BBB CB   1 
ATOM   4514 C CG   . MET B 2 78  ? -9.340  -0.827  50.479 1.000 55.420  ? 79   MET BBB CG   1 
ATOM   4515 S SD   . MET B 2 78  ? -7.723  -1.647  50.667 1.000 57.620  ? 79   MET BBB SD   1 
ATOM   4516 C CE   . MET B 2 78  ? -7.819  -2.190  52.370 1.000 62.560  ? 79   MET BBB CE   1 
ATOM   4517 H H    . MET B 2 78  ? -11.358 -1.520  47.801 1.000 49.780  ? 79   MET BBB H    1 
ATOM   4518 H HA   . MET B 2 78  ? -9.655  -3.337  49.326 1.000 48.720  ? 79   MET BBB HA   1 
ATOM   4519 H HB2  . MET B 2 78  ? -11.350 -1.265  50.378 1.000 51.280  ? 79   MET BBB HB2  1 
ATOM   4520 H HB3  . MET B 2 78  ? -10.554 -2.274  51.301 1.000 51.280  ? 79   MET BBB HB3  1 
ATOM   4521 H HG2  . MET B 2 78  ? -9.324  -0.311  49.645 1.000 55.420  ? 79   MET BBB HG2  1 
ATOM   4522 H HG3  . MET B 2 78  ? -9.450  -0.198  51.223 1.000 55.420  ? 79   MET BBB HG3  1 
ATOM   4523 H HE1  . MET B 2 78  ? -7.009  -2.649  52.605 1.000 62.560  ? 79   MET BBB HE1  1 
ATOM   4524 H HE2  . MET B 2 78  ? -7.933  -1.428  52.942 1.000 62.560  ? 79   MET BBB HE2  1 
ATOM   4525 H HE3  . MET B 2 78  ? -8.570  -2.787  52.475 1.000 62.560  ? 79   MET BBB HE3  1 
ATOM   4526 N N    . VAL B 2 79  ? -11.455 -4.776  50.262 1.000 53.970  ? 80   VAL BBB N    1 
ATOM   4527 C CA   . VAL B 2 79  ? -12.530 -5.654  50.805 1.000 54.220  ? 80   VAL BBB CA   1 
ATOM   4528 C C    . VAL B 2 79  ? -12.203 -5.923  52.292 1.000 52.930  ? 80   VAL BBB C    1 
ATOM   4529 O O    . VAL B 2 79  ? -11.022 -5.845  52.698 1.000 52.690  ? 80   VAL BBB O    1 
ATOM   4530 C CB   . VAL B 2 79  ? -12.680 -6.909  49.918 1.000 50.560  ? 80   VAL BBB CB   1 
ATOM   4531 C CG1  . VAL B 2 79  ? -11.367 -7.633  49.773 1.000 62.520  ? 80   VAL BBB CG1  1 
ATOM   4532 C CG2  . VAL B 2 79  ? -13.754 -7.874  50.407 1.000 51.710  ? 80   VAL BBB CG2  1 
ATOM   4533 H H    . VAL B 2 79  ? -10.492 -4.977  50.492 1.000 53.970  ? 80   VAL BBB H    1 
ATOM   4534 H HA   . VAL B 2 79  ? -13.377 -5.176  50.746 1.000 54.220  ? 80   VAL BBB HA   1 
ATOM   4535 H HB   . VAL B 2 79  ? -12.959 -6.602  49.020 1.000 50.560  ? 80   VAL BBB HB   1 
ATOM   4536 H HG11 . VAL B 2 79  ? -10.713 -7.040  49.364 1.000 62.520  ? 80   VAL BBB HG11 1 
ATOM   4537 H HG12 . VAL B 2 79  ? -11.489 -8.418  49.211 1.000 62.520  ? 80   VAL BBB HG12 1 
ATOM   4538 H HG13 . VAL B 2 79  ? -11.050 -7.909  50.650 1.000 62.520  ? 80   VAL BBB HG13 1 
ATOM   4539 H HG21 . VAL B 2 79  ? -13.534 -8.177  51.305 1.000 51.710  ? 80   VAL BBB HG21 1 
ATOM   4540 H HG22 . VAL B 2 79  ? -13.799 -8.640  49.809 1.000 51.710  ? 80   VAL BBB HG22 1 
ATOM   4541 H HG23 . VAL B 2 79  ? -14.616 -7.422  50.420 1.000 51.710  ? 80   VAL BBB HG23 1 
ATOM   4542 N N    . TYR B 2 80  ? -13.225 -6.144  53.109 1.000 47.510  ? 81   TYR BBB N    1 
ATOM   4543 C CA   . TYR B 2 80  ? -13.112 -6.131  54.585 1.000 47.070  ? 81   TYR BBB CA   1 
ATOM   4544 C C    . TYR B 2 80  ? -13.849 -7.352  55.134 1.000 46.220  ? 81   TYR BBB C    1 
ATOM   4545 O O    . TYR B 2 80  ? -14.822 -7.829  54.484 1.000 43.580  ? 81   TYR BBB O    1 
ATOM   4546 C CB   . TYR B 2 80  ? -13.660 -4.812  55.145 1.000 43.370  ? 81   TYR BBB CB   1 
ATOM   4547 C CG   . TYR B 2 80  ? -13.030 -3.556  54.589 1.000 46.100  ? 81   TYR BBB CG   1 
ATOM   4548 C CD1  . TYR B 2 80  ? -11.766 -3.148  54.996 1.000 49.740  ? 81   TYR BBB CD1  1 
ATOM   4549 C CD2  . TYR B 2 80  ? -13.697 -2.760  53.664 1.000 46.640  ? 81   TYR BBB CD2  1 
ATOM   4550 C CE1  . TYR B 2 80  ? -11.175 -1.996  54.492 1.000 51.160  ? 81   TYR BBB CE1  1 
ATOM   4551 C CE2  . TYR B 2 80  ? -13.121 -1.609  53.146 1.000 49.030  ? 81   TYR BBB CE2  1 
ATOM   4552 C CZ   . TYR B 2 80  ? -11.854 -1.220  53.563 1.000 53.990  ? 81   TYR BBB CZ   1 
ATOM   4553 O OH   . TYR B 2 80  ? -11.277 -0.076  53.067 1.000 54.720  ? 81   TYR BBB OH   1 
ATOM   4554 H H    . TYR B 2 80  ? -14.123 -6.330  52.685 1.000 47.510  ? 81   TYR BBB H    1 
ATOM   4555 H HA   . TYR B 2 80  ? -12.154 -6.196  54.829 1.000 47.070  ? 81   TYR BBB HA   1 
ATOM   4556 H HB2  . TYR B 2 80  ? -14.624 -4.778  54.971 1.000 43.370  ? 81   TYR BBB HB2  1 
ATOM   4557 H HB3  . TYR B 2 80  ? -13.540 -4.815  56.118 1.000 43.370  ? 81   TYR BBB HB3  1 
ATOM   4558 H HD1  . TYR B 2 80  ? -11.296 -3.665  55.629 1.000 49.740  ? 81   TYR BBB HD1  1 
ATOM   4559 H HD2  . TYR B 2 80  ? -14.562 -3.009  53.382 1.000 46.640  ? 81   TYR BBB HD2  1 
ATOM   4560 H HE1  . TYR B 2 80  ? -10.316 -1.738  54.783 1.000 51.160  ? 81   TYR BBB HE1  1 
ATOM   4561 H HE2  . TYR B 2 80  ? -13.590 -1.088  52.515 1.000 49.030  ? 81   TYR BBB HE2  1 
ATOM   4562 H HH   . TYR B 2 80  ? -10.541 -0.267  52.670 0.000 54.720  ? 81   TYR BBB HH   1 
ATOM   4563 N N    . LEU B 2 81  ? -13.397 -7.856  56.285 1.000 48.220  ? 82   LEU BBB N    1 
ATOM   4564 C CA   . LEU B 2 81  ? -14.137 -8.873  57.087 1.000 46.710  ? 82   LEU BBB CA   1 
ATOM   4565 C C    . LEU B 2 81  ? -14.218 -8.377  58.518 1.000 47.260  ? 82   LEU BBB C    1 
ATOM   4566 O O    . LEU B 2 81  ? -13.177 -8.363  59.216 1.000 45.810  ? 82   LEU BBB O    1 
ATOM   4567 C CB   . LEU B 2 81  ? -13.435 -10.227 57.034 1.000 44.780  ? 82   LEU BBB CB   1 
ATOM   4568 C CG   . LEU B 2 81  ? -14.186 -11.394 57.663 1.000 46.100  ? 82   LEU BBB CG   1 
ATOM   4569 C CD1  . LEU B 2 81  ? -15.393 -11.781 56.840 1.000 45.560  ? 82   LEU BBB CD1  1 
ATOM   4570 C CD2  . LEU B 2 81  ? -13.275 -12.596 57.833 1.000 49.650  ? 82   LEU BBB CD2  1 
ATOM   4571 H H    . LEU B 2 81  ? -12.504 -7.521  56.618 1.000 48.220  ? 82   LEU BBB H    1 
ATOM   4572 H HA   . LEU B 2 81  ? -15.047 -8.959  56.719 1.000 46.710  ? 82   LEU BBB HA   1 
ATOM   4573 H HB2  . LEU B 2 81  ? -13.260 -10.446 56.097 1.000 44.780  ? 82   LEU BBB HB2  1 
ATOM   4574 H HB3  . LEU B 2 81  ? -12.570 -10.143 57.483 1.000 44.780  ? 82   LEU BBB HB3  1 
ATOM   4575 H HG   . LEU B 2 81  ? -14.493 -11.113 58.560 1.000 46.100  ? 82   LEU BBB HG   1 
ATOM   4576 H HD11 . LEU B 2 81  ? -15.999 -11.022 56.776 1.000 45.560  ? 82   LEU BBB HD11 1 
ATOM   4577 H HD12 . LEU B 2 81  ? -15.850 -12.527 57.265 1.000 45.560  ? 82   LEU BBB HD12 1 
ATOM   4578 H HD13 . LEU B 2 81  ? -15.107 -12.043 55.948 1.000 45.560  ? 82   LEU BBB HD13 1 
ATOM   4579 H HD21 . LEU B 2 81  ? -12.937 -12.873 56.964 1.000 49.650  ? 82   LEU BBB HD21 1 
ATOM   4580 H HD22 . LEU B 2 81  ? -13.774 -13.327 58.236 1.000 49.650  ? 82   LEU BBB HD22 1 
ATOM   4581 H HD23 . LEU B 2 81  ? -12.528 -12.358 58.409 1.000 49.650  ? 82   LEU BBB HD23 1 
ATOM   4582 N N    . GLN B 2 82  ? -15.408 -7.913  58.888 1.000 53.070  ? 83   GLN BBB N    1 
ATOM   4583 C CA   . GLN B 2 82  ? -15.718 -7.513  60.275 1.000 47.700  ? 83   GLN BBB CA   1 
ATOM   4584 C C    . GLN B 2 82  ? -16.048 -8.818  60.979 1.000 47.510  ? 83   GLN BBB C    1 
ATOM   4585 O O    . GLN B 2 82  ? -16.940 -9.564  60.476 1.000 42.340  ? 83   GLN BBB O    1 
ATOM   4586 C CB   . GLN B 2 82  ? -16.845 -6.486  60.376 1.000 43.960  ? 83   GLN BBB CB   1 
ATOM   4587 C CG   . GLN B 2 82  ? -17.172 -6.111  61.819 1.000 45.320  ? 83   GLN BBB CG   1 
ATOM   4588 C CD   . GLN B 2 82  ? -16.024 -5.433  62.524 1.000 46.380  ? 83   GLN BBB CD   1 
ATOM   4589 O OE1  . GLN B 2 82  ? -15.509 -4.419  62.069 1.000 62.460  ? 83   GLN BBB OE1  1 
ATOM   4590 N NE2  . GLN B 2 82  ? -15.580 -5.996  63.633 1.000 42.370  ? 83   GLN BBB NE2  1 
ATOM   4591 H H    . GLN B 2 82  ? -16.125 -7.835  58.181 1.000 53.070  ? 83   GLN BBB H    1 
ATOM   4592 H HA   . GLN B 2 82  ? -14.917 -7.093  60.665 1.000 47.700  ? 83   GLN BBB HA   1 
ATOM   4593 H HB2  . GLN B 2 82  ? -16.581 -5.683  59.880 1.000 43.960  ? 83   GLN BBB HB2  1 
ATOM   4594 H HB3  . GLN B 2 82  ? -17.643 -6.855  59.944 1.000 43.960  ? 83   GLN BBB HB3  1 
ATOM   4595 H HG2  . GLN B 2 82  ? -17.947 -5.509  61.828 1.000 45.320  ? 83   GLN BBB HG2  1 
ATOM   4596 H HG3  . GLN B 2 82  ? -17.412 -6.922  62.316 1.000 45.320  ? 83   GLN BBB HG3  1 
ATOM   4597 H HE21 . GLN B 2 82  ? -14.909 -5.630  64.077 0.000 42.370  ? 83   GLN BBB HE21 1 
ATOM   4598 H HE22 . GLN B 2 82  ? -15.954 -6.739  63.932 0.000 42.370  ? 83   GLN BBB HE22 1 
ATOM   4599 N N    . MET B 2 83  ? -15.267 -9.090  62.030 1.000 49.910  ? 84   MET BBB N    1 
ATOM   4600 C CA   . MET B 2 83  ? -15.374 -10.269 62.933 1.000 48.170  ? 84   MET BBB CA   1 
ATOM   4601 C C    . MET B 2 83  ? -15.906 -9.795  64.287 1.000 44.870  ? 84   MET BBB C    1 
ATOM   4602 O O    . MET B 2 83  ? -15.411 -8.762  64.814 1.000 46.120  ? 84   MET BBB O    1 
ATOM   4603 C CB   . MET B 2 83  ? -13.999 -10.923 63.090 1.000 51.790  ? 84   MET BBB CB   1 
ATOM   4604 C CG   . MET B 2 83  ? -13.479 -11.509 61.796 1.000 51.510  ? 84   MET BBB CG   1 
ATOM   4605 S SD   . MET B 2 83  ? -11.999 -12.505 62.013 1.000 58.530  ? 84   MET BBB SD   1 
ATOM   4606 C CE   . MET B 2 83  ? -10.863 -11.153 62.237 1.000 53.110  ? 84   MET BBB CE   1 
ATOM   4607 H H    . MET B 2 83  ? -14.543 -8.405  62.198 1.000 49.910  ? 84   MET BBB H    1 
ATOM   4608 H HA   . MET B 2 83  ? -16.013 -10.907 62.539 1.000 48.170  ? 84   MET BBB HA   1 
ATOM   4609 H HB2  . MET B 2 83  ? -13.368 -10.251 63.418 1.000 51.790  ? 84   MET BBB HB2  1 
ATOM   4610 H HB3  . MET B 2 83  ? -14.064 -11.630 63.763 1.000 51.790  ? 84   MET BBB HB3  1 
ATOM   4611 H HG2  . MET B 2 83  ? -14.176 -12.070 61.393 1.000 51.510  ? 84   MET BBB HG2  1 
ATOM   4612 H HG3  . MET B 2 83  ? -13.276 -10.781 61.171 1.000 51.510  ? 84   MET BBB HG3  1 
ATOM   4613 H HE1  . MET B 2 83  ? -9.978  -11.499 62.374 1.000 53.110  ? 84   MET BBB HE1  1 
ATOM   4614 H HE2  . MET B 2 83  ? -10.872 -10.595 61.456 1.000 53.110  ? 84   MET BBB HE2  1 
ATOM   4615 H HE3  . MET B 2 83  ? -11.129 -10.635 63.006 1.000 53.110  ? 84   MET BBB HE3  1 
ATOM   4616 N N    . ASN B 2 84  ? -16.936 -10.462 64.791 1.000 48.080  ? 85   ASN BBB N    1 
ATOM   4617 C CA   . ASN B 2 84  ? -17.755 -9.974  65.941 1.000 48.990  ? 85   ASN BBB CA   1 
ATOM   4618 C C    . ASN B 2 84  ? -17.946 -11.146 66.895 1.000 48.890  ? 85   ASN BBB C    1 
ATOM   4619 O O    . ASN B 2 84  ? -18.198 -12.228 66.377 1.000 45.300  ? 85   ASN BBB O    1 
ATOM   4620 C CB   . ASN B 2 84  ? -19.143 -9.486  65.499 1.000 48.600  ? 85   ASN BBB CB   1 
ATOM   4621 C CG   . ASN B 2 84  ? -19.131 -8.198  64.694 1.000 48.900  ? 85   ASN BBB CG   1 
ATOM   4622 O OD1  . ASN B 2 84  ? -18.393 -7.258  65.013 1.000 46.870  ? 85   ASN BBB OD1  1 
ATOM   4623 N ND2  . ASN B 2 84  ? -19.957 -8.154  63.653 1.000 47.500  ? 85   ASN BBB ND2  1 
ATOM   4624 H H    . ASN B 2 84  ? -17.167 -11.347 64.363 1.000 48.080  ? 85   ASN BBB H    1 
ATOM   4625 H HA   . ASN B 2 84  ? -17.258 -9.254  66.395 1.000 48.990  ? 85   ASN BBB HA   1 
ATOM   4626 H HB2  . ASN B 2 84  ? -19.567 -10.183 64.957 1.000 48.600  ? 85   ASN BBB HB2  1 
ATOM   4627 H HB3  . ASN B 2 84  ? -19.698 -9.347  66.293 1.000 48.600  ? 85   ASN BBB HB3  1 
ATOM   4628 H HD21 . ASN B 2 84  ? -19.993 -7.430  63.148 0.000 47.500  ? 85   ASN BBB HD21 1 
ATOM   4629 H HD22 . ASN B 2 84  ? -20.470 -8.849  63.466 0.000 47.500  ? 85   ASN BBB HD22 1 
ATOM   4630 N N    . SER B 2 85  ? -17.863 -10.946 68.215 1.000 52.040  ? 86   SER BBB N    1 
ATOM   4631 C CA   . SER B 2 85  ? -18.198 -11.995 69.218 1.000 48.440  ? 86   SER BBB CA   1 
ATOM   4632 C C    . SER B 2 85  ? -17.379 -13.255 68.903 1.000 53.320  ? 86   SER BBB C    1 
ATOM   4633 O O    . SER B 2 85  ? -17.976 -14.368 68.761 1.000 51.890  ? 86   SER BBB O    1 
ATOM   4634 C CB   . SER B 2 85  ? -19.687 -12.318 69.243 1.000 46.970  ? 86   SER BBB CB   1 
ATOM   4635 O OG   . SER B 2 85  ? -20.450 -11.193 69.640 1.000 51.140  ? 86   SER BBB OG   1 
ATOM   4636 H H    . SER B 2 85  ? -17.474 -10.079 68.558 1.000 52.040  ? 86   SER BBB H    1 
ATOM   4637 H HA   . SER B 2 85  ? -17.935 -11.658 70.116 1.000 48.440  ? 86   SER BBB HA   1 
ATOM   4638 H HB2  . SER B 2 85  ? -19.973 -12.603 68.346 1.000 46.970  ? 86   SER BBB HB2  1 
ATOM   4639 H HB3  . SER B 2 85  ? -19.849 -13.057 69.872 1.000 46.970  ? 86   SER BBB HB3  1 
ATOM   4640 H HG   . SER B 2 85  ? -21.268 -11.410 69.642 0.000 51.140  ? 86   SER BBB HG   1 
ATOM   4641 N N    . LEU B 2 86  ? -16.056 -13.105 68.819 1.000 55.770  ? 87   LEU BBB N    1 
ATOM   4642 C CA   . LEU B 2 86  ? -15.155 -14.179 68.326 1.000 59.800  ? 87   LEU BBB CA   1 
ATOM   4643 C C    . LEU B 2 86  ? -15.108 -15.363 69.294 1.000 66.800  ? 87   LEU BBB C    1 
ATOM   4644 O O    . LEU B 2 86  ? -15.213 -15.162 70.524 1.000 62.320  ? 87   LEU BBB O    1 
ATOM   4645 C CB   . LEU B 2 86  ? -13.768 -13.587 68.079 1.000 60.790  ? 87   LEU BBB CB   1 
ATOM   4646 C CG   . LEU B 2 86  ? -13.636 -12.896 66.720 1.000 62.110  ? 87   LEU BBB CG   1 
ATOM   4647 C CD1  . LEU B 2 86  ? -12.298 -12.197 66.570 1.000 60.600  ? 87   LEU BBB CD1  1 
ATOM   4648 C CD2  . LEU B 2 86  ? -13.865 -13.887 65.586 1.000 57.920  ? 87   LEU BBB CD2  1 
ATOM   4649 H H    . LEU B 2 86  ? -15.659 -12.221 69.104 1.000 55.770  ? 87   LEU BBB H    1 
ATOM   4650 H HA   . LEU B 2 86  ? -15.504 -14.509 67.466 1.000 59.800  ? 87   LEU BBB HA   1 
ATOM   4651 H HB2  . LEU B 2 86  ? -13.576 -12.946 68.792 1.000 60.790  ? 87   LEU BBB HB2  1 
ATOM   4652 H HB3  . LEU B 2 86  ? -13.110 -14.307 68.145 1.000 60.790  ? 87   LEU BBB HB3  1 
ATOM   4653 H HG   . LEU B 2 86  ? -14.333 -12.197 66.663 1.000 62.110  ? 87   LEU BBB HG   1 
ATOM   4654 H HD11 . LEU B 2 86  ? -12.204 -11.523 67.266 1.000 60.600  ? 87   LEU BBB HD11 1 
ATOM   4655 H HD12 . LEU B 2 86  ? -12.250 -11.771 65.696 1.000 60.600  ? 87   LEU BBB HD12 1 
ATOM   4656 H HD13 . LEU B 2 86  ? -11.580 -12.849 66.652 1.000 60.600  ? 87   LEU BBB HD13 1 
ATOM   4657 H HD21 . LEU B 2 86  ? -13.206 -14.601 65.641 1.000 57.920  ? 87   LEU BBB HD21 1 
ATOM   4658 H HD22 . LEU B 2 86  ? -13.778 -13.429 64.732 1.000 57.920  ? 87   LEU BBB HD22 1 
ATOM   4659 H HD23 . LEU B 2 86  ? -14.759 -14.265 65.661 1.000 57.920  ? 87   LEU BBB HD23 1 
ATOM   4660 N N    . ARG B 2 87  ? -14.925 -16.564 68.741 1.000 70.060  ? 88   ARG BBB N    1 
ATOM   4661 C CA   . ARG B 2 87  ? -14.796 -17.823 69.523 1.000 68.050  ? 88   ARG BBB CA   1 
ATOM   4662 C C    . ARG B 2 87  ? -13.435 -18.498 69.296 1.000 67.350  ? 88   ARG BBB C    1 
ATOM   4663 O O    . ARG B 2 87  ? -12.606 -18.016 68.488 1.000 69.950  ? 88   ARG BBB O    1 
ATOM   4664 C CB   . ARG B 2 87  ? -15.946 -18.764 69.178 1.000 68.990  ? 88   ARG BBB CB   1 
ATOM   4665 C CG   . ARG B 2 87  ? -17.303 -18.207 69.570 1.000 73.960  ? 88   ARG BBB CG   1 
ATOM   4666 C CD   . ARG B 2 87  ? -18.371 -18.862 68.734 1.000 79.880  ? 88   ARG BBB CD   1 
ATOM   4667 N NE   . ARG B 2 87  ? -18.297 -20.315 68.836 1.000 87.550  ? 88   ARG BBB NE   1 
ATOM   4668 C CZ   . ARG B 2 87  ? -19.131 -21.087 69.528 1.000 88.100  ? 88   ARG BBB CZ   1 
ATOM   4669 N NH1  . ARG B 2 87  ? -20.134 -20.559 70.205 1.000 91.270  ? 88   ARG BBB NH1  1 
ATOM   4670 N NH2  . ARG B 2 87  ? -18.963 -22.399 69.533 1.000 93.670  ? 88   ARG BBB NH2  1 
ATOM   4671 H H    . ARG B 2 87  ? -14.873 -16.603 67.733 1.000 70.060  ? 88   ARG BBB H    1 
ATOM   4672 H HA   . ARG B 2 87  ? -14.864 -17.604 70.481 1.000 68.050  ? 88   ARG BBB HA   1 
ATOM   4673 H HB2  . ARG B 2 87  ? -15.930 -18.935 68.213 1.000 68.990  ? 88   ARG BBB HB2  1 
ATOM   4674 H HB3  . ARG B 2 87  ? -15.799 -19.617 69.637 1.000 68.990  ? 88   ARG BBB HB3  1 
ATOM   4675 H HG2  . ARG B 2 87  ? -17.460 -18.377 70.523 1.000 73.960  ? 88   ARG BBB HG2  1 
ATOM   4676 H HG3  . ARG B 2 87  ? -17.306 -17.236 69.433 1.000 73.960  ? 88   ARG BBB HG3  1 
ATOM   4677 H HD2  . ARG B 2 87  ? -19.252 -18.551 69.034 1.000 79.880  ? 88   ARG BBB HD2  1 
ATOM   4678 H HD3  . ARG B 2 87  ? -18.262 -18.587 67.799 1.000 79.880  ? 88   ARG BBB HD3  1 
ATOM   4679 H HE   . ARG B 2 87  ? -17.654 -20.721 68.410 1.000 87.550  ? 88   ARG BBB HE   1 
ATOM   4680 H HH11 . ARG B 2 87  ? -20.255 -19.688 70.200 1.000 91.270  ? 88   ARG BBB HH11 1 
ATOM   4681 H HH12 . ARG B 2 87  ? -20.678 -21.080 70.658 1.000 91.270  ? 88   ARG BBB HH12 1 
ATOM   4682 H HH21 . ARG B 2 87  ? -18.299 -22.758 69.078 1.000 93.670  ? 88   ARG BBB HH21 1 
ATOM   4683 H HH22 . ARG B 2 87  ? -19.515 -22.910 69.991 1.000 93.670  ? 88   ARG BBB HH22 1 
ATOM   4684 N N    . ALA B 2 88  ? -13.212 -19.582 70.033 1.000 63.580  ? 89   ALA BBB N    1 
ATOM   4685 C CA   . ALA B 2 88  ? -11.974 -20.382 70.009 1.000 63.850  ? 89   ALA BBB CA   1 
ATOM   4686 C C    . ALA B 2 88  ? -11.730 -20.901 68.592 1.000 60.920  ? 89   ALA BBB C    1 
ATOM   4687 O O    . ALA B 2 88  ? -10.628 -20.691 68.055 1.000 68.750  ? 89   ALA BBB O    1 
ATOM   4688 C CB   . ALA B 2 88  ? -12.115 -21.523 70.981 1.000 64.510  ? 89   ALA BBB CB   1 
ATOM   4689 H H    . ALA B 2 88  ? -13.964 -19.857 70.648 1.000 63.580  ? 89   ALA BBB H    1 
ATOM   4690 H HA   . ALA B 2 88  ? -11.220 -19.800 70.265 1.000 63.850  ? 89   ALA BBB HA   1 
ATOM   4691 H HB1  . ALA B 2 88  ? -11.305 -22.057 70.974 1.000 64.510  ? 89   ALA BBB HB1  1 
ATOM   4692 H HB2  . ALA B 2 88  ? -12.262 -21.173 71.874 1.000 64.510  ? 89   ALA BBB HB2  1 
ATOM   4693 H HB3  . ALA B 2 88  ? -12.870 -22.078 70.724 1.000 64.510  ? 89   ALA BBB HB3  1 
ATOM   4694 N N    . GLU B 2 89  ? -12.734 -21.575 68.045 1.000 52.560  ? 90   GLU BBB N    1 
ATOM   4695 C CA   . GLU B 2 89  ? -12.756 -22.154 66.676 1.000 60.280  ? 90   GLU BBB CA   1 
ATOM   4696 C C    . GLU B 2 89  ? -12.500 -21.118 65.544 1.000 57.110  ? 90   GLU BBB C    1 
ATOM   4697 O O    . GLU B 2 89  ? -12.260 -21.540 64.407 1.000 61.400  ? 90   GLU BBB O    1 
ATOM   4698 C CB   . GLU B 2 89  ? -14.108 -22.850 66.535 1.000 65.940  ? 90   GLU BBB CB   1 
ATOM   4699 C CG   . GLU B 2 89  ? -15.244 -22.121 67.231 1.000 75.380  ? 90   GLU BBB CG   1 
ATOM   4700 C CD   . GLU B 2 89  ? -16.601 -22.471 66.650 1.000 82.840  ? 90   GLU BBB CD   1 
ATOM   4701 O OE1  . GLU B 2 89  ? -17.024 -23.625 66.833 1.000 92.180  ? 90   GLU BBB OE1  1 
ATOM   4702 O OE2  . GLU B 2 89  ? -17.207 -21.603 65.980 1.000 78.920  ? 90   GLU BBB OE2  1 
ATOM   4703 H H    . GLU B 2 89  ? -13.542 -21.687 68.640 1.000 52.560  ? 90   GLU BBB H    1 
ATOM   4704 H HA   . GLU B 2 89  ? -12.037 -22.824 66.609 1.000 60.280  ? 90   GLU BBB HA   1 
ATOM   4705 H HB2  . GLU B 2 89  ? -14.320 -22.928 65.582 1.000 65.940  ? 90   GLU BBB HB2  1 
ATOM   4706 H HB3  . GLU B 2 89  ? -14.035 -23.752 66.911 1.000 65.940  ? 90   GLU BBB HB3  1 
ATOM   4707 H HG2  . GLU B 2 89  ? -15.228 -22.346 68.186 1.000 75.380  ? 90   GLU BBB HG2  1 
ATOM   4708 H HG3  . GLU B 2 89  ? -15.095 -21.154 67.156 1.000 75.380  ? 90   GLU BBB HG3  1 
ATOM   4709 N N    . ASP B 2 90  ? -12.532 -19.811 65.812 1.000 54.850  ? 91   ASP BBB N    1 
ATOM   4710 C CA   . ASP B 2 90  ? -12.285 -18.740 64.807 1.000 53.790  ? 91   ASP BBB CA   1 
ATOM   4711 C C    . ASP B 2 90  ? -10.786 -18.469 64.689 1.000 54.940  ? 91   ASP BBB C    1 
ATOM   4712 O O    . ASP B 2 90  ? -10.399 -17.643 63.846 1.000 52.500  ? 91   ASP BBB O    1 
ATOM   4713 C CB   . ASP B 2 90  ? -13.073 -17.467 65.143 1.000 48.870  ? 91   ASP BBB CB   1 
ATOM   4714 C CG   . ASP B 2 90  ? -14.582 -17.694 65.048 1.000 55.520  ? 91   ASP BBB CG   1 
ATOM   4715 O OD1  . ASP B 2 90  ? -15.007 -18.515 64.155 1.000 47.770  ? 91   ASP BBB OD1  1 
ATOM   4716 O OD2  . ASP B 2 90  ? -15.347 -17.081 65.879 1.000 54.930  ? 91   ASP BBB OD2  1 
ATOM   4717 H H    . ASP B 2 90  ? -12.739 -19.553 66.766 1.000 54.850  ? 91   ASP BBB H    1 
ATOM   4718 H HA   . ASP B 2 90  ? -12.616 -19.050 63.932 1.000 53.790  ? 91   ASP BBB HA   1 
ATOM   4719 H HB2  . ASP B 2 90  ? -12.853 -17.199 66.059 1.000 48.870  ? 91   ASP BBB HB2  1 
ATOM   4720 H HB3  . ASP B 2 90  ? -12.820 -16.768 64.506 1.000 48.870  ? 91   ASP BBB HB3  1 
ATOM   4721 N N    . THR B 2 91  ? -9.973  -19.139 65.505 1.000 55.210  ? 92   THR BBB N    1 
ATOM   4722 C CA   . THR B 2 91  ? -8.493  -19.173 65.362 1.000 54.700  ? 92   THR BBB CA   1 
ATOM   4723 C C    . THR B 2 91  ? -8.164  -19.935 64.071 1.000 54.000  ? 92   THR BBB C    1 
ATOM   4724 O O    . THR B 2 91  ? -8.727  -21.082 63.857 1.000 49.410  ? 92   THR BBB O    1 
ATOM   4725 C CB   . THR B 2 91  ? -7.788  -19.795 66.580 1.000 54.770  ? 92   THR BBB CB   1 
ATOM   4726 O OG1  . THR B 2 91  ? -8.044  -18.954 67.716 1.000 47.240  ? 92   THR BBB OG1  1 
ATOM   4727 C CG2  . THR B 2 91  ? -6.297  -19.964 66.338 1.000 46.930  ? 92   THR BBB CG2  1 
ATOM   4728 H H    . THR B 2 91  ? -10.407 -19.649 66.261 1.000 55.210  ? 92   THR BBB H    1 
ATOM   4729 H HA   . THR B 2 91  ? -8.173  -18.245 65.284 1.000 54.700  ? 92   THR BBB HA   1 
ATOM   4730 H HB   . THR B 2 91  ? -8.194  -20.677 66.756 1.000 54.770  ? 92   THR BBB HB   1 
ATOM   4731 H HG1  . THR B 2 91  ? -7.664  -19.278 68.401 0.000 47.240  ? 92   THR BBB HG1  1 
ATOM   4732 H HG21 . THR B 2 91  ? -6.155  -20.548 65.571 1.000 46.930  ? 92   THR BBB HG21 1 
ATOM   4733 H HG22 . THR B 2 91  ? -5.882  -20.360 67.125 1.000 46.930  ? 92   THR BBB HG22 1 
ATOM   4734 H HG23 . THR B 2 91  ? -5.895  -19.095 66.162 1.000 46.930  ? 92   THR BBB HG23 1 
ATOM   4735 N N    . ALA B 2 92  ? -7.356  -19.305 63.218 1.000 47.240  ? 93   ALA BBB N    1 
ATOM   4736 C CA   . ALA B 2 92  ? -7.033  -19.817 61.861 1.000 49.470  ? 93   ALA BBB CA   1 
ATOM   4737 C C    . ALA B 2 92  ? -6.240  -18.761 61.101 1.000 46.200  ? 93   ALA BBB C    1 
ATOM   4738 O O    . ALA B 2 92  ? -6.080  -17.619 61.644 1.000 43.150  ? 93   ALA BBB O    1 
ATOM   4739 C CB   . ALA B 2 92  ? -8.279  -20.242 61.118 1.000 46.830  ? 93   ALA BBB CB   1 
ATOM   4740 H H    . ALA B 2 92  ? -6.949  -18.433 63.525 1.000 47.240  ? 93   ALA BBB H    1 
ATOM   4741 H HA   . ALA B 2 92  ? -6.475  -20.625 61.955 1.000 49.470  ? 93   ALA BBB HA   1 
ATOM   4742 H HB1  . ALA B 2 92  ? -8.036  -20.570 60.238 1.000 46.830  ? 93   ALA BBB HB1  1 
ATOM   4743 H HB2  . ALA B 2 92  ? -8.727  -20.946 61.612 1.000 46.830  ? 93   ALA BBB HB2  1 
ATOM   4744 H HB3  . ALA B 2 92  ? -8.877  -19.482 61.025 1.000 46.830  ? 93   ALA BBB HB3  1 
ATOM   4745 N N    . VAL B 2 93  ? -5.672  -19.162 59.951 1.000 50.040  ? 94   VAL BBB N    1 
ATOM   4746 C CA   . VAL B 2 93  ? -5.152  -18.207 58.914 1.000 49.290  ? 94   VAL BBB CA   1 
ATOM   4747 C C    . VAL B 2 93  ? -6.318  -17.865 57.985 1.000 43.830  ? 94   VAL BBB C    1 
ATOM   4748 O O    . VAL B 2 93  ? -7.010  -18.818 57.530 1.000 37.990  ? 94   VAL BBB O    1 
ATOM   4749 C CB   . VAL B 2 93  ? -3.969  -18.791 58.125 1.000 55.660  ? 94   VAL BBB CB   1 
ATOM   4750 C CG1  . VAL B 2 93  ? -3.555  -17.914 56.959 1.000 53.870  ? 94   VAL BBB CG1  1 
ATOM   4751 C CG2  . VAL B 2 93  ? -2.788  -19.039 59.041 1.000 58.770  ? 94   VAL BBB CG2  1 
ATOM   4752 H H    . VAL B 2 93  ? -5.597  -20.156 59.787 1.000 50.040  ? 94   VAL BBB H    1 
ATOM   4753 H HA   . VAL B 2 93  ? -4.853  -17.397 59.365 1.000 49.290  ? 94   VAL BBB HA   1 
ATOM   4754 H HB   . VAL B 2 93  ? -4.262  -19.661 57.758 1.000 55.660  ? 94   VAL BBB HB   1 
ATOM   4755 H HG11 . VAL B 2 93  ? -4.303  -17.815 56.345 1.000 53.870  ? 94   VAL BBB HG11 1 
ATOM   4756 H HG12 . VAL B 2 93  ? -2.806  -18.325 56.494 1.000 53.870  ? 94   VAL BBB HG12 1 
ATOM   4757 H HG13 . VAL B 2 93  ? -3.290  -17.038 57.289 1.000 53.870  ? 94   VAL BBB HG13 1 
ATOM   4758 H HG21 . VAL B 2 93  ? -2.512  -18.200 59.449 1.000 58.770  ? 94   VAL BBB HG21 1 
ATOM   4759 H HG22 . VAL B 2 93  ? -2.050  -19.408 58.526 1.000 58.770  ? 94   VAL BBB HG22 1 
ATOM   4760 H HG23 . VAL B 2 93  ? -3.044  -19.669 59.737 1.000 58.770  ? 94   VAL BBB HG23 1 
ATOM   4761 N N    . TYR B 2 94  ? -6.554  -16.569 57.776 1.000 46.570  ? 95   TYR BBB N    1 
ATOM   4762 C CA   . TYR B 2 94  ? -7.689  -16.003 56.995 1.000 51.150  ? 95   TYR BBB CA   1 
ATOM   4763 C C    . TYR B 2 94  ? -7.127  -15.561 55.637 1.000 46.980  ? 95   TYR BBB C    1 
ATOM   4764 O O    . TYR B 2 94  ? -6.187  -14.737 55.631 1.000 45.520  ? 95   TYR BBB O    1 
ATOM   4765 C CB   . TYR B 2 94  ? -8.385  -14.880 57.801 1.000 48.490  ? 95   TYR BBB CB   1 
ATOM   4766 C CG   . TYR B 2 94  ? -9.360  -15.412 58.827 1.000 47.100  ? 95   TYR BBB CG   1 
ATOM   4767 C CD1  . TYR B 2 94  ? -8.952  -15.674 60.123 1.000 52.130  ? 95   TYR BBB CD1  1 
ATOM   4768 C CD2  . TYR B 2 94  ? -10.651 -15.773 58.488 1.000 46.730  ? 95   TYR BBB CD2  1 
ATOM   4769 C CE1  . TYR B 2 94  ? -9.800  -16.246 61.058 1.000 51.060  ? 95   TYR BBB CE1  1 
ATOM   4770 C CE2  . TYR B 2 94  ? -11.529 -16.307 59.418 1.000 48.620  ? 95   TYR BBB CE2  1 
ATOM   4771 C CZ   . TYR B 2 94  ? -11.097 -16.566 60.709 1.000 52.100  ? 95   TYR BBB CZ   1 
ATOM   4772 O OH   . TYR B 2 94  ? -11.916 -17.142 61.645 1.000 43.490  ? 95   TYR BBB OH   1 
ATOM   4773 H H    . TYR B 2 94  ? -5.885  -15.941 58.198 1.000 46.570  ? 95   TYR BBB H    1 
ATOM   4774 H HA   . TYR B 2 94  ? -8.365  -16.715 56.858 1.000 51.150  ? 95   TYR BBB HA   1 
ATOM   4775 H HB2  . TYR B 2 94  ? -7.695  -14.343 58.244 1.000 48.490  ? 95   TYR BBB HB2  1 
ATOM   4776 H HB3  . TYR B 2 94  ? -8.852  -14.291 57.172 1.000 48.490  ? 95   TYR BBB HB3  1 
ATOM   4777 H HD1  . TYR B 2 94  ? -8.054  -15.517 60.365 1.000 52.130  ? 95   TYR BBB HD1  1 
ATOM   4778 H HD2  . TYR B 2 94  ? -10.940 -15.652 57.599 1.000 46.730  ? 95   TYR BBB HD2  1 
ATOM   4779 H HE1  . TYR B 2 94  ? -9.495  -16.413 61.934 1.000 51.060  ? 95   TYR BBB HE1  1 
ATOM   4780 H HE2  . TYR B 2 94  ? -12.412 -16.520 59.165 1.000 48.620  ? 95   TYR BBB HE2  1 
ATOM   4781 H HH   . TYR B 2 94  ? -12.003 -16.620 62.320 0.000 43.490  ? 95   TYR BBB HH   1 
ATOM   4782 N N    . TYR B 2 95  ? -7.665  -16.089 54.536 1.000 48.200  ? 96   TYR BBB N    1 
ATOM   4783 C CA   . TYR B 2 95  ? -7.274  -15.705 53.145 1.000 51.030  ? 96   TYR BBB CA   1 
ATOM   4784 C C    . TYR B 2 95  ? -8.411  -14.958 52.447 1.000 46.930  ? 96   TYR BBB C    1 
ATOM   4785 O O    . TYR B 2 95  ? -9.536  -15.445 52.424 1.000 51.720  ? 96   TYR BBB O    1 
ATOM   4786 C CB   . TYR B 2 95  ? -6.900  -16.911 52.270 1.000 51.210  ? 96   TYR BBB CB   1 
ATOM   4787 C CG   . TYR B 2 95  ? -5.788  -17.765 52.815 1.000 48.270  ? 96   TYR BBB CG   1 
ATOM   4788 C CD1  . TYR B 2 95  ? -4.478  -17.338 52.743 1.000 48.960  ? 96   TYR BBB CD1  1 
ATOM   4789 C CD2  . TYR B 2 95  ? -6.056  -18.972 53.449 1.000 52.450  ? 96   TYR BBB CD2  1 
ATOM   4790 C CE1  . TYR B 2 95  ? -3.457  -18.107 53.272 1.000 54.890  ? 96   TYR BBB CE1  1 
ATOM   4791 C CE2  . TYR B 2 95  ? -5.050  -19.748 53.998 1.000 48.890  ? 96   TYR BBB CE2  1 
ATOM   4792 C CZ   . TYR B 2 95  ? -3.746  -19.307 53.907 1.000 54.780  ? 96   TYR BBB CZ   1 
ATOM   4793 O OH   . TYR B 2 95  ? -2.732  -20.044 54.429 1.000 56.350  ? 96   TYR BBB OH   1 
ATOM   4794 H H    . TYR B 2 95  ? -8.379  -16.790 54.671 1.000 48.200  ? 96   TYR BBB H    1 
ATOM   4795 H HA   . TYR B 2 95  ? -6.495  -15.094 53.193 1.000 51.030  ? 96   TYR BBB HA   1 
ATOM   4796 H HB2  . TYR B 2 95  ? -7.698  -17.468 52.152 1.000 51.210  ? 96   TYR BBB HB2  1 
ATOM   4797 H HB3  . TYR B 2 95  ? -6.641  -16.582 51.384 1.000 51.210  ? 96   TYR BBB HB3  1 
ATOM   4798 H HD1  . TYR B 2 95  ? -4.285  -16.504 52.348 1.000 48.960  ? 96   TYR BBB HD1  1 
ATOM   4799 H HD2  . TYR B 2 95  ? -6.949  -19.269 53.506 1.000 52.450  ? 96   TYR BBB HD2  1 
ATOM   4800 H HE1  . TYR B 2 95  ? -2.564  -17.810 53.220 1.000 54.890  ? 96   TYR BBB HE1  1 
ATOM   4801 H HE2  . TYR B 2 95  ? -5.243  -20.564 54.430 1.000 48.890  ? 96   TYR BBB HE2  1 
ATOM   4802 H HH   . TYR B 2 95  ? -2.315  -19.589 55.025 0.000 56.350  ? 96   TYR BBB HH   1 
ATOM   4803 N N    . CYS B 2 96  ? -8.070  -13.824 51.848 1.000 53.000  ? 97   CYS BBB N    1 
ATOM   4804 C CA   . CYS B 2 96  ? -8.855  -13.044 50.853 1.000 50.410  ? 97   CYS BBB CA   1 
ATOM   4805 C C    . CYS B 2 96  ? -8.638  -13.639 49.461 1.000 49.500  ? 97   CYS BBB C    1 
ATOM   4806 O O    . CYS B 2 96  ? -7.448  -13.760 49.109 1.000 48.060  ? 97   CYS BBB O    1 
ATOM   4807 C CB   . CYS B 2 96  ? -8.287  -11.634 50.889 1.000 56.870  ? 97   CYS BBB CB   1 
ATOM   4808 S SG   . CYS B 2 96  ? -8.899  -10.521 49.607 1.000 56.590  ? 97   CYS BBB SG   1 
ATOM   4809 H H    . CYS B 2 96  ? -7.161  -13.487 52.132 1.000 53.000  ? 97   CYS BBB H    1 
ATOM   4810 H HA   . CYS B 2 96  ? -9.808  -13.126 51.086 1.000 50.410  ? 97   CYS BBB HA   1 
ATOM   4811 H HB2  . CYS B 2 96  ? -8.493  -11.227 51.756 1.000 56.870  ? 97   CYS BBB HB2  1 
ATOM   4812 H HB3  . CYS B 2 96  ? -7.313  -11.678 50.801 1.000 56.870  ? 97   CYS BBB HB3  1 
ATOM   4813 N N    . ALA B 2 97  ? -9.699  -13.994 48.722 1.000 41.520  ? 98   ALA BBB N    1 
ATOM   4814 C CA   . ALA B 2 97  ? -9.623  -14.492 47.331 1.000 42.400  ? 98   ALA BBB CA   1 
ATOM   4815 C C    . ALA B 2 97  ? -10.576 -13.735 46.384 1.000 42.720  ? 98   ALA BBB C    1 
ATOM   4816 O O    . ALA B 2 97  ? -11.415 -12.958 46.855 1.000 47.000  ? 98   ALA BBB O    1 
ATOM   4817 C CB   . ALA B 2 97  ? -9.874  -15.974 47.299 1.000 43.550  ? 98   ALA BBB CB   1 
ATOM   4818 H H    . ALA B 2 97  ? -10.602 -13.907 49.165 1.000 41.520  ? 98   ALA BBB H    1 
ATOM   4819 H HA   . ALA B 2 97  ? -8.706  -14.350 46.997 1.000 42.400  ? 98   ALA BBB HA   1 
ATOM   4820 H HB1  . ALA B 2 97  ? -9.823  -16.292 46.384 1.000 43.550  ? 98   ALA BBB HB1  1 
ATOM   4821 H HB2  . ALA B 2 97  ? -9.206  -16.428 47.836 1.000 43.550  ? 98   ALA BBB HB2  1 
ATOM   4822 H HB3  . ALA B 2 97  ? -10.758 -16.162 47.657 1.000 43.550  ? 98   ALA BBB HB3  1 
ATOM   4823 N N    . ALA B 2 98  ? -10.385 -13.915 45.074 1.000 42.920  ? 99   ALA BBB N    1 
ATOM   4824 C CA   . ALA B 2 98  ? -11.154 -13.273 43.982 1.000 39.890  ? 99   ALA BBB CA   1 
ATOM   4825 C C    . ALA B 2 98  ? -11.463 -14.316 42.912 1.000 43.240  ? 99   ALA BBB C    1 
ATOM   4826 O O    . ALA B 2 98  ? -10.519 -15.093 42.549 1.000 39.940  ? 99   ALA BBB O    1 
ATOM   4827 C CB   . ALA B 2 98  ? -10.379 -12.126 43.392 1.000 39.860  ? 99   ALA BBB CB   1 
ATOM   4828 H H    . ALA B 2 98  ? -9.639  -14.555 44.841 1.000 42.920  ? 99   ALA BBB H    1 
ATOM   4829 H HA   . ALA B 2 98  ? -12.003 -12.936 44.353 1.000 39.890  ? 99   ALA BBB HA   1 
ATOM   4830 H HB1  . ALA B 2 98  ? -10.896 -11.717 42.680 1.000 39.860  ? 99   ALA BBB HB1  1 
ATOM   4831 H HB2  . ALA B 2 98  ? -10.201 -11.466 44.080 1.000 39.860  ? 99   ALA BBB HB2  1 
ATOM   4832 H HB3  . ALA B 2 98  ? -9.537  -12.453 43.033 1.000 39.860  ? 99   ALA BBB HB3  1 
ATOM   4833 N N    . ALA B 2 99  ? -12.717 -14.308 42.426 1.000 44.740  ? 100  ALA BBB N    1 
ATOM   4834 C CA   . ALA B 2 99  ? -13.230 -15.168 41.335 1.000 42.710  ? 100  ALA BBB CA   1 
ATOM   4835 C C    . ALA B 2 99  ? -12.708 -14.646 40.002 1.000 46.700  ? 100  ALA BBB C    1 
ATOM   4836 O O    . ALA B 2 99  ? -12.958 -13.463 39.634 1.000 47.650  ? 100  ALA BBB O    1 
ATOM   4837 C CB   . ALA B 2 99  ? -14.742 -15.221 41.342 1.000 46.460  ? 100  ALA BBB CB   1 
ATOM   4838 H H    . ALA B 2 99  ? -13.340 -13.645 42.865 1.000 44.740  ? 100  ALA BBB H    1 
ATOM   4839 H HA   . ALA B 2 99  ? -12.891 -16.084 41.472 1.000 42.710  ? 100  ALA BBB HA   1 
ATOM   4840 H HB1  . ALA B 2 99  ? -15.050 -15.789 40.619 1.000 46.460  ? 100  ALA BBB HB1  1 
ATOM   4841 H HB2  . ALA B 2 99  ? -15.050 -15.581 42.188 1.000 46.460  ? 100  ALA BBB HB2  1 
ATOM   4842 H HB3  . ALA B 2 99  ? -15.099 -14.325 41.223 1.000 46.460  ? 100  ALA BBB HB3  1 
ATOM   4843 N N    . GLY B 2 100 ? -12.003 -15.515 39.293 1.000 53.820  ? 101  GLY BBB N    1 
ATOM   4844 C CA   . GLY B 2 100 ? -11.495 -15.230 37.949 1.000 49.350  ? 101  GLY BBB CA   1 
ATOM   4845 C C    . GLY B 2 100 ? -12.236 -16.030 36.912 1.000 49.300  ? 101  GLY BBB C    1 
ATOM   4846 O O    . GLY B 2 100 ? -12.025 -15.738 35.755 1.000 53.330  ? 101  GLY BBB O    1 
ATOM   4847 H H    . GLY B 2 100 ? -11.813 -16.415 39.711 1.000 53.820  ? 101  GLY BBB H    1 
ATOM   4848 H HA2  . GLY B 2 100 ? -11.598 -14.263 37.763 1.000 49.350  ? 101  GLY BBB HA2  1 
ATOM   4849 H HA3  . GLY B 2 100 ? -10.530 -15.449 37.915 1.000 49.350  ? 101  GLY BBB HA3  1 
ATOM   4850 N N    . VAL B 2 101 ? -13.043 -17.019 37.298 1.000 54.320  ? 102  VAL BBB N    1 
ATOM   4851 C CA   . VAL B 2 101 ? -13.913 -17.763 36.340 1.000 57.070  ? 102  VAL BBB CA   1 
ATOM   4852 C C    . VAL B 2 101 ? -15.100 -16.870 35.953 1.000 52.640  ? 102  VAL BBB C    1 
ATOM   4853 O O    . VAL B 2 101 ? -15.900 -16.579 36.856 1.000 47.590  ? 102  VAL BBB O    1 
ATOM   4854 C CB   . VAL B 2 101 ? -14.393 -19.097 36.940 1.000 65.770  ? 102  VAL BBB CB   1 
ATOM   4855 C CG1  . VAL B 2 101 ? -15.368 -19.817 36.006 1.000 62.270  ? 102  VAL BBB CG1  1 
ATOM   4856 C CG2  . VAL B 2 101 ? -13.215 -19.986 37.295 1.000 64.380  ? 102  VAL BBB CG2  1 
ATOM   4857 H H    . VAL B 2 101 ? -13.062 -17.269 38.276 1.000 54.320  ? 102  VAL BBB H    1 
ATOM   4858 H HA   . VAL B 2 101 ? -13.394 -17.953 35.538 1.000 57.070  ? 102  VAL BBB HA   1 
ATOM   4859 H HB   . VAL B 2 101 ? -14.879 -18.885 37.775 1.000 65.770  ? 102  VAL BBB HB   1 
ATOM   4860 H HG11 . VAL B 2 101 ? -16.145 -19.253 35.850 1.000 62.270  ? 102  VAL BBB HG11 1 
ATOM   4861 H HG12 . VAL B 2 101 ? -15.651 -20.654 36.414 1.000 62.270  ? 102  VAL BBB HG12 1 
ATOM   4862 H HG13 . VAL B 2 101 ? -14.928 -20.003 35.158 1.000 62.270  ? 102  VAL BBB HG13 1 
ATOM   4863 H HG21 . VAL B 2 101 ? -12.695 -20.172 36.494 1.000 64.380  ? 102  VAL BBB HG21 1 
ATOM   4864 H HG22 . VAL B 2 101 ? -13.541 -20.822 37.672 1.000 64.380  ? 102  VAL BBB HG22 1 
ATOM   4865 H HG23 . VAL B 2 101 ? -12.652 -19.534 37.948 1.000 64.380  ? 102  VAL BBB HG23 1 
ATOM   4866 N N    . ARG B 2 102 ? -15.219 -16.493 34.667 1.000 47.350  ? 103  ARG BBB N    1 
ATOM   4867 C CA   . ARG B 2 102 ? -16.339 -15.690 34.094 1.000 48.170  ? 103  ARG BBB CA   1 
ATOM   4868 C C    . ARG B 2 102 ? -16.495 -14.393 34.895 1.000 48.590  ? 103  ARG BBB C    1 
ATOM   4869 O O    . ARG B 2 102 ? -17.637 -14.008 35.248 1.000 53.420  ? 103  ARG BBB O    1 
ATOM   4870 C CB   . ARG B 2 102 ? -17.656 -16.466 34.114 1.000 55.040  ? 103  ARG BBB CB   1 
ATOM   4871 C CG   . ARG B 2 102 ? -17.652 -17.783 33.348 1.000 68.890  ? 103  ARG BBB CG   1 
ATOM   4872 C CD   . ARG B 2 102 ? -18.980 -18.543 33.424 1.000 74.370  ? 103  ARG BBB CD   1 
ATOM   4873 N NE   . ARG B 2 102 ? -19.655 -18.385 34.715 1.000 89.410  ? 103  ARG BBB NE   1 
ATOM   4874 C CZ   . ARG B 2 102 ? -19.501 -19.168 35.790 1.000 90.230  ? 103  ARG BBB CZ   1 
ATOM   4875 N NH1  . ARG B 2 102 ? -18.693 -20.221 35.762 1.000 90.540  ? 103  ARG BBB NH1  1 
ATOM   4876 N NH2  . ARG B 2 102 ? -20.163 -18.874 36.897 1.000 87.020  ? 103  ARG BBB NH2  1 
ATOM   4877 H H    . ARG B 2 102 ? -14.469 -16.795 34.061 1.000 47.350  ? 103  ARG BBB H    1 
ATOM   4878 H HA   . ARG B 2 102 ? -16.115 -15.462 33.162 1.000 48.170  ? 103  ARG BBB HA   1 
ATOM   4879 H HB2  . ARG B 2 102 ? -17.891 -16.657 35.046 1.000 55.040  ? 103  ARG BBB HB2  1 
ATOM   4880 H HB3  . ARG B 2 102 ? -18.359 -15.897 33.737 1.000 55.040  ? 103  ARG BBB HB3  1 
ATOM   4881 H HG2  . ARG B 2 102 ? -17.451 -17.608 32.404 1.000 68.890  ? 103  ARG BBB HG2  1 
ATOM   4882 H HG3  . ARG B 2 102 ? -16.945 -18.362 33.704 1.000 68.890  ? 103  ARG BBB HG3  1 
ATOM   4883 H HD2  . ARG B 2 102 ? -19.576 -18.224 32.713 1.000 74.370  ? 103  ARG BBB HD2  1 
ATOM   4884 H HD3  . ARG B 2 102 ? -18.815 -19.497 33.266 1.000 74.370  ? 103  ARG BBB HD3  1 
ATOM   4885 H HE   . ARG B 2 102 ? -20.213 -17.721 34.805 1.000 89.410  ? 103  ARG BBB HE   1 
ATOM   4886 H HH11 . ARG B 2 102 ? -18.249 -20.412 35.028 1.000 90.540  ? 103  ARG BBB HH11 1 
ATOM   4887 H HH12 . ARG B 2 102 ? -18.604 -20.724 36.478 1.000 90.540  ? 103  ARG BBB HH12 1 
ATOM   4888 H HH21 . ARG B 2 102 ? -20.695 -18.172 36.917 1.000 87.020  ? 103  ARG BBB HH21 1 
ATOM   4889 H HH22 . ARG B 2 102 ? -20.070 -19.381 37.611 1.000 87.020  ? 103  ARG BBB HH22 1 
ATOM   4890 N N    . ALA B 2 103 ? -15.380 -13.725 35.150 1.000 43.560  ? 104  ALA BBB N    1 
ATOM   4891 C CA   . ALA B 2 103 ? -15.274 -12.475 35.929 1.000 46.370  ? 104  ALA BBB CA   1 
ATOM   4892 C C    . ALA B 2 103 ? -16.374 -11.449 35.591 1.000 44.560  ? 104  ALA BBB C    1 
ATOM   4893 O O    . ALA B 2 103 ? -16.722 -10.653 36.518 1.000 45.860  ? 104  ALA BBB O    1 
ATOM   4894 C CB   . ALA B 2 103 ? -13.902 -11.896 35.693 1.000 44.680  ? 104  ALA BBB CB   1 
ATOM   4895 H H    . ALA B 2 103 ? -14.543 -14.135 34.761 1.000 43.560  ? 104  ALA BBB H    1 
ATOM   4896 H HA   . ALA B 2 103 ? -15.373 -12.693 36.886 1.000 46.370  ? 104  ALA BBB HA   1 
ATOM   4897 H HB1  . ALA B 2 103 ? -13.807 -11.072 36.195 1.000 44.680  ? 104  ALA BBB HB1  1 
ATOM   4898 H HB2  . ALA B 2 103 ? -13.228 -12.530 35.984 1.000 44.680  ? 104  ALA BBB HB2  1 
ATOM   4899 H HB3  . ALA B 2 103 ? -13.785 -11.712 34.746 1.000 44.680  ? 104  ALA BBB HB3  1 
ATOM   4900 N N    . GLU B 2 104 ? -16.825 -11.376 34.330 1.000 42.290  ? 105  GLU BBB N    1 
ATOM   4901 C CA   . GLU B 2 104 ? -17.801 -10.349 33.857 1.000 43.080  ? 105  GLU BBB CA   1 
ATOM   4902 C C    . GLU B 2 104 ? -19.087 -10.480 34.674 1.000 41.740  ? 105  GLU BBB C    1 
ATOM   4903 O O    . GLU B 2 104 ? -19.725 -9.442  34.923 1.000 43.350  ? 105  GLU BBB O    1 
ATOM   4904 C CB   . GLU B 2 104 ? -18.077 -10.404 32.341 1.000 48.890  ? 105  GLU BBB CB   1 
ATOM   4905 C CG   . GLU B 2 104 ? -18.659 -11.720 31.810 1.000 48.100  ? 105  GLU BBB CG   1 
ATOM   4906 C CD   . GLU B 2 104 ? -17.623 -12.819 31.610 1.000 56.450  ? 105  GLU BBB CD   1 
ATOM   4907 O OE1  . GLU B 2 104 ? -16.389 -12.526 31.739 1.000 58.280  ? 105  GLU BBB OE1  1 
ATOM   4908 O OE2  . GLU B 2 104 ? -18.038 -13.970 31.337 1.000 57.340  ? 105  GLU BBB OE2  1 
ATOM   4909 H H    . GLU B 2 104 ? -16.475 -12.061 33.676 1.000 42.290  ? 105  GLU BBB H    1 
ATOM   4910 H HA   . GLU B 2 104 ? -17.413 -9.456  34.009 1.000 43.080  ? 105  GLU BBB HA   1 
ATOM   4911 H HB2  . GLU B 2 104 ? -18.707 -9.689  32.113 1.000 48.890  ? 105  GLU BBB HB2  1 
ATOM   4912 H HB3  . GLU B 2 104 ? -17.236 -10.239 31.865 1.000 48.890  ? 105  GLU BBB HB3  1 
ATOM   4913 H HG2  . GLU B 2 104 ? -19.342 -12.041 32.436 1.000 48.100  ? 105  GLU BBB HG2  1 
ATOM   4914 H HG3  . GLU B 2 104 ? -19.105 -11.548 30.953 1.000 48.100  ? 105  GLU BBB HG3  1 
ATOM   4915 N N    . ASP B 2 105 ? -19.436 -11.692 35.114 1.000 44.200  ? 106  ASP BBB N    1 
ATOM   4916 C CA   . ASP B 2 105 ? -20.631 -11.941 35.970 1.000 44.010  ? 106  ASP BBB CA   1 
ATOM   4917 C C    . ASP B 2 105 ? -20.259 -11.694 37.436 1.000 45.460  ? 106  ASP BBB C    1 
ATOM   4918 O O    . ASP B 2 105 ? -19.585 -12.550 38.017 1.000 51.170  ? 106  ASP BBB O    1 
ATOM   4919 C CB   . ASP B 2 105 ? -21.133 -13.368 35.774 1.000 45.670  ? 106  ASP BBB CB   1 
ATOM   4920 C CG   . ASP B 2 105 ? -22.193 -13.756 36.775 1.000 45.490  ? 106  ASP BBB CG   1 
ATOM   4921 O OD1  . ASP B 2 105 ? -22.531 -12.909 37.616 1.000 44.500  ? 106  ASP BBB OD1  1 
ATOM   4922 O OD2  . ASP B 2 105 ? -22.668 -14.907 36.699 1.000 44.400  ? 106  ASP BBB OD2  1 
ATOM   4923 H H    . ASP B 2 105 ? -18.852 -12.471 34.846 1.000 44.200  ? 106  ASP BBB H    1 
ATOM   4924 H HA   . ASP B 2 105 ? -21.340 -11.307 35.710 1.000 44.010  ? 106  ASP BBB HA   1 
ATOM   4925 H HB2  . ASP B 2 105 ? -21.519 -13.441 34.877 1.000 45.670  ? 106  ASP BBB HB2  1 
ATOM   4926 H HB3  . ASP B 2 105 ? -20.376 -13.980 35.878 1.000 45.670  ? 106  ASP BBB HB3  1 
ATOM   4927 N N    . GLY B 2 106 ? -20.671 -10.570 38.016 1.000 42.480  ? 107  GLY BBB N    1 
ATOM   4928 C CA   . GLY B 2 106 ? -20.228 -10.167 39.364 1.000 42.850  ? 107  GLY BBB CA   1 
ATOM   4929 C C    . GLY B 2 106 ? -21.117 -10.676 40.498 1.000 40.200  ? 107  GLY BBB C    1 
ATOM   4930 O O    . GLY B 2 106 ? -21.064 -10.100 41.603 1.000 43.490  ? 107  GLY BBB O    1 
ATOM   4931 H H    . GLY B 2 106 ? -21.311 -9.975  37.509 1.000 42.480  ? 107  GLY BBB H    1 
ATOM   4932 H HA2  . GLY B 2 106 ? -19.311 -10.506 39.518 1.000 42.850  ? 107  GLY BBB HA2  1 
ATOM   4933 H HA3  . GLY B 2 106 ? -20.203 -9.179  39.414 1.000 42.850  ? 107  GLY BBB HA3  1 
ATOM   4934 N N    . ARG B 2 107 ? -21.901 -11.721 40.273 1.000 40.390  ? 108  ARG BBB N    1 
ATOM   4935 C CA   . ARG B 2 107 ? -22.791 -12.282 41.317 1.000 42.140  ? 108  ARG BBB CA   1 
ATOM   4936 C C    . ARG B 2 107 ? -21.909 -12.948 42.367 1.000 43.810  ? 108  ARG BBB C    1 
ATOM   4937 O O    . ARG B 2 107 ? -20.749 -13.232 42.060 1.000 42.140  ? 108  ARG BBB O    1 
ATOM   4938 C CB   . ARG B 2 107 ? -23.827 -13.196 40.662 1.000 45.880  ? 108  ARG BBB CB   1 
ATOM   4939 C CG   . ARG B 2 107 ? -24.903 -12.375 39.962 1.000 50.470  ? 108  ARG BBB CG   1 
ATOM   4940 C CD   . ARG B 2 107 ? -25.931 -13.180 39.228 1.000 53.440  ? 108  ARG BBB CD   1 
ATOM   4941 N NE   . ARG B 2 107 ? -25.343 -13.942 38.129 1.000 60.720  ? 108  ARG BBB NE   1 
ATOM   4942 C CZ   . ARG B 2 107 ? -25.957 -14.953 37.518 1.000 61.150  ? 108  ARG BBB CZ   1 
ATOM   4943 N NH1  . ARG B 2 107 ? -27.169 -15.304 37.904 1.000 67.590  ? 108  ARG BBB NH1  1 
ATOM   4944 N NH2  . ARG B 2 107 ? -25.383 -15.624 36.537 1.000 60.450  ? 108  ARG BBB NH2  1 
ATOM   4945 H H    . ARG B 2 107 ? -21.888 -12.146 39.357 1.000 40.390  ? 108  ARG BBB H    1 
ATOM   4946 H HA   . ARG B 2 107 ? -23.294 -11.542 41.729 1.000 42.140  ? 108  ARG BBB HA   1 
ATOM   4947 H HB2  . ARG B 2 107 ? -23.368 -13.779 40.021 1.000 45.880  ? 108  ARG BBB HB2  1 
ATOM   4948 H HB3  . ARG B 2 107 ? -24.224 -13.764 41.355 1.000 45.880  ? 108  ARG BBB HB3  1 
ATOM   4949 H HG2  . ARG B 2 107 ? -25.373 -11.825 40.625 1.000 50.470  ? 108  ARG BBB HG2  1 
ATOM   4950 H HG3  . ARG B 2 107 ? -24.480 -11.771 39.315 1.000 50.470  ? 108  ARG BBB HG3  1 
ATOM   4951 H HD2  . ARG B 2 107 ? -26.367 -13.795 39.855 1.000 53.440  ? 108  ARG BBB HD2  1 
ATOM   4952 H HD3  . ARG B 2 107 ? -26.621 -12.578 38.876 1.000 53.440  ? 108  ARG BBB HD3  1 
ATOM   4953 H HE   . ARG B 2 107 ? -24.544 -13.719 37.860 1.000 60.720  ? 108  ARG BBB HE   1 
ATOM   4954 H HH11 . ARG B 2 107 ? -27.562 -14.870 38.560 1.000 67.590  ? 108  ARG BBB HH11 1 
ATOM   4955 H HH12 . ARG B 2 107 ? -27.580 -15.971 37.504 1.000 67.590  ? 108  ARG BBB HH12 1 
ATOM   4956 H HH21 . ARG B 2 107 ? -24.572 -15.405 36.272 1.000 60.450  ? 108  ARG BBB HH21 1 
ATOM   4957 H HH22 . ARG B 2 107 ? -25.813 -16.289 36.150 1.000 60.450  ? 108  ARG BBB HH22 1 
ATOM   4958 N N    . VAL B 2 108 ? -22.416 -13.072 43.594 1.000 45.880  ? 109  VAL BBB N    1 
ATOM   4959 C CA   . VAL B 2 108 ? -21.725 -13.746 44.730 1.000 43.780  ? 109  VAL BBB CA   1 
ATOM   4960 C C    . VAL B 2 108 ? -21.438 -15.162 44.271 1.000 39.330  ? 109  VAL BBB C    1 
ATOM   4961 O O    . VAL B 2 108 ? -22.315 -15.755 43.622 1.000 39.800  ? 109  VAL BBB O    1 
ATOM   4962 C CB   . VAL B 2 108 ? -22.552 -13.769 46.032 1.000 45.980  ? 109  VAL BBB CB   1 
ATOM   4963 C CG1  . VAL B 2 108 ? -21.707 -14.182 47.224 1.000 47.110  ? 109  VAL BBB CG1  1 
ATOM   4964 C CG2  . VAL B 2 108 ? -23.143 -12.416 46.332 1.000 53.560  ? 109  VAL BBB CG2  1 
ATOM   4965 H H    . VAL B 2 108 ? -23.333 -12.674 43.741 1.000 45.880  ? 109  VAL BBB H    1 
ATOM   4966 H HA   . VAL B 2 108 ? -20.887 -13.280 44.900 1.000 43.780  ? 109  VAL BBB HA   1 
ATOM   4967 H HB   . VAL B 2 108 ? -23.300 -14.401 45.893 1.000 45.980  ? 109  VAL BBB HB   1 
ATOM   4968 H HG11 . VAL B 2 108 ? -21.346 -15.073 47.074 1.000 47.110  ? 109  VAL BBB HG11 1 
ATOM   4969 H HG12 . VAL B 2 108 ? -22.257 -14.186 48.027 1.000 47.110  ? 109  VAL BBB HG12 1 
ATOM   4970 H HG13 . VAL B 2 108 ? -20.975 -13.552 47.337 1.000 47.110  ? 109  VAL BBB HG13 1 
ATOM   4971 H HG21 . VAL B 2 108 ? -22.428 -11.764 46.432 1.000 53.560  ? 109  VAL BBB HG21 1 
ATOM   4972 H HG22 . VAL B 2 108 ? -23.658 -12.462 47.156 1.000 53.560  ? 109  VAL BBB HG22 1 
ATOM   4973 H HG23 . VAL B 2 108 ? -23.726 -12.147 45.601 1.000 53.560  ? 109  VAL BBB HG23 1 
ATOM   4974 N N    . ARG B 2 109 ? -20.247 -15.642 44.581 1.000 40.580  ? 110  ARG BBB N    1 
ATOM   4975 C CA   . ARG B 2 109 ? -19.756 -17.000 44.219 1.000 48.150  ? 110  ARG BBB CA   1 
ATOM   4976 C C    . ARG B 2 109 ? -19.554 -17.827 45.503 1.000 49.980  ? 110  ARG BBB C    1 
ATOM   4977 O O    . ARG B 2 109 ? -18.797 -17.374 46.405 1.000 48.510  ? 110  ARG BBB O    1 
ATOM   4978 C CB   . ARG B 2 109 ? -18.427 -16.838 43.473 1.000 49.960  ? 110  ARG BBB CB   1 
ATOM   4979 C CG   . ARG B 2 109 ? -18.542 -16.034 42.186 1.000 56.840  ? 110  ARG BBB CG   1 
ATOM   4980 C CD   . ARG B 2 109 ? -19.064 -16.867 41.022 1.000 64.840  ? 110  ARG BBB CD   1 
ATOM   4981 N NE   . ARG B 2 109 ? -18.366 -16.557 39.774 1.000 64.860  ? 110  ARG BBB NE   1 
ATOM   4982 C CZ   . ARG B 2 109 ? -18.597 -15.452 39.099 1.000 69.030  ? 110  ARG BBB CZ   1 
ATOM   4983 N NH1  . ARG B 2 109 ? -19.514 -14.608 39.543 1.000 84.250  ? 110  ARG BBB NH1  1 
ATOM   4984 N NH2  . ARG B 2 109 ? -17.936 -15.186 37.994 1.000 63.020  ? 110  ARG BBB NH2  1 
ATOM   4985 H H    . ARG B 2 109 ? -19.643 -15.023 45.102 1.000 40.580  ? 110  ARG BBB H    1 
ATOM   4986 H HA   . ARG B 2 109 ? -20.438 -17.441 43.662 1.000 48.150  ? 110  ARG BBB HA   1 
ATOM   4987 H HB2  . ARG B 2 109 ? -17.787 -16.396 44.069 1.000 49.960  ? 110  ARG BBB HB2  1 
ATOM   4988 H HB3  . ARG B 2 109 ? -18.077 -17.729 43.262 1.000 49.960  ? 110  ARG BBB HB3  1 
ATOM   4989 H HG2  . ARG B 2 109 ? -19.148 -15.276 42.331 1.000 56.840  ? 110  ARG BBB HG2  1 
ATOM   4990 H HG3  . ARG B 2 109 ? -17.660 -15.675 41.949 1.000 56.840  ? 110  ARG BBB HG3  1 
ATOM   4991 H HD2  . ARG B 2 109 ? -18.952 -17.819 41.231 1.000 64.840  ? 110  ARG BBB HD2  1 
ATOM   4992 H HD3  . ARG B 2 109 ? -20.024 -16.699 40.910 1.000 64.840  ? 110  ARG BBB HD3  1 
ATOM   4993 H HE   . ARG B 2 109 ? -17.781 -17.133 39.480 1.000 64.860  ? 110  ARG BBB HE   1 
ATOM   4994 H HH11 . ARG B 2 109 ? -19.958 -14.791 40.279 1.000 84.250  ? 110  ARG BBB HH11 1 
ATOM   4995 H HH12 . ARG B 2 109 ? -19.677 -13.866 39.100 1.000 84.250  ? 110  ARG BBB HH12 1 
ATOM   4996 H HH21 . ARG B 2 109 ? -17.330 -15.753 37.698 1.000 63.020  ? 110  ARG BBB HH21 1 
ATOM   4997 H HH22 . ARG B 2 109 ? -18.101 -14.442 37.552 1.000 63.020  ? 110  ARG BBB HH22 1 
ATOM   4998 N N    . THR B 2 110 ? -20.178 -18.994 45.598 1.000 45.920  ? 111  THR BBB N    1 
ATOM   4999 C CA   . THR B 2 110 ? -20.034 -19.899 46.770 1.000 48.360  ? 111  THR BBB CA   1 
ATOM   5000 C C    . THR B 2 110 ? -19.110 -21.090 46.419 1.000 49.310  ? 111  THR BBB C    1 
ATOM   5001 O O    . THR B 2 110 ? -18.447 -21.585 47.337 1.000 57.680  ? 111  THR BBB O    1 
ATOM   5002 C CB   . THR B 2 110 ? -21.415 -20.247 47.345 1.000 44.130  ? 111  THR BBB CB   1 
ATOM   5003 O OG1  . THR B 2 110 ? -22.122 -21.049 46.402 1.000 51.580  ? 111  THR BBB OG1  1 
ATOM   5004 C CG2  . THR B 2 110 ? -22.258 -19.031 47.648 1.000 43.790  ? 111  THR BBB CG2  1 
ATOM   5005 H H    . THR B 2 110 ? -20.776 -19.271 44.833 1.000 45.920  ? 111  THR BBB H    1 
ATOM   5006 H HA   . THR B 2 110 ? -19.613 -19.388 47.500 1.000 48.360  ? 111  THR BBB HA   1 
ATOM   5007 H HB   . THR B 2 110 ? -21.283 -20.755 48.181 1.000 44.130  ? 111  THR BBB HB   1 
ATOM   5008 H HG1  . THR B 2 110 ? -22.886 -21.246 46.712 0.000 51.580  ? 111  THR BBB HG1  1 
ATOM   5009 H HG21 . THR B 2 110 ? -21.801 -18.472 48.302 1.000 43.790  ? 111  THR BBB HG21 1 
ATOM   5010 H HG22 . THR B 2 110 ? -23.118 -19.312 48.009 1.000 43.790  ? 111  THR BBB HG22 1 
ATOM   5011 H HG23 . THR B 2 110 ? -22.401 -18.521 46.830 1.000 43.790  ? 111  THR BBB HG23 1 
ATOM   5012 N N    . LEU B 2 111 ? -18.983 -21.494 45.152 1.000 51.110  ? 112  LEU BBB N    1 
ATOM   5013 C CA   . LEU B 2 111 ? -18.160 -22.669 44.749 1.000 56.790  ? 112  LEU BBB CA   1 
ATOM   5014 C C    . LEU B 2 111 ? -16.677 -22.303 44.864 1.000 58.730  ? 112  LEU BBB C    1 
ATOM   5015 O O    . LEU B 2 111 ? -16.216 -21.397 44.174 1.000 63.910  ? 112  LEU BBB O    1 
ATOM   5016 C CB   . LEU B 2 111 ? -18.543 -23.080 43.322 1.000 61.720  ? 112  LEU BBB CB   1 
ATOM   5017 C CG   . LEU B 2 111 ? -17.728 -24.229 42.724 1.000 74.520  ? 112  LEU BBB CG   1 
ATOM   5018 C CD1  . LEU B 2 111 ? -17.867 -25.511 43.542 1.000 72.030  ? 112  LEU BBB CD1  1 
ATOM   5019 C CD2  . LEU B 2 111 ? -18.121 -24.461 41.269 1.000 78.230  ? 112  LEU BBB CD2  1 
ATOM   5020 H H    . LEU B 2 111 ? -19.473 -20.969 44.442 1.000 51.110  ? 112  LEU BBB H    1 
ATOM   5021 H HA   . LEU B 2 111 ? -18.354 -23.413 45.365 1.000 56.790  ? 112  LEU BBB HA   1 
ATOM   5022 H HB2  . LEU B 2 111 ? -19.487 -23.336 43.319 1.000 61.720  ? 112  LEU BBB HB2  1 
ATOM   5023 H HB3  . LEU B 2 111 ? -18.448 -22.299 42.741 1.000 61.720  ? 112  LEU BBB HB3  1 
ATOM   5024 H HG   . LEU B 2 111 ? -16.773 -23.973 42.750 1.000 74.520  ? 112  LEU BBB HG   1 
ATOM   5025 H HD11 . LEU B 2 111 ? -17.552 -25.353 44.449 1.000 72.030  ? 112  LEU BBB HD11 1 
ATOM   5026 H HD12 . LEU B 2 111 ? -17.337 -26.217 43.132 1.000 72.030  ? 112  LEU BBB HD12 1 
ATOM   5027 H HD13 . LEU B 2 111 ? -18.802 -25.781 43.566 1.000 72.030  ? 112  LEU BBB HD13 1 
ATOM   5028 H HD21 . LEU B 2 111 ? -19.067 -24.684 41.220 1.000 78.230  ? 112  LEU BBB HD21 1 
ATOM   5029 H HD22 . LEU B 2 111 ? -17.594 -25.193 40.903 1.000 78.230  ? 112  LEU BBB HD22 1 
ATOM   5030 H HD23 . LEU B 2 111 ? -17.952 -23.653 40.754 1.000 78.230  ? 112  LEU BBB HD23 1 
ATOM   5031 N N    . PRO B 2 112 ? -15.886 -22.942 45.763 1.000 57.440  ? 113  PRO BBB N    1 
ATOM   5032 C CA   . PRO B 2 112 ? -14.485 -22.555 45.966 1.000 53.420  ? 113  PRO BBB CA   1 
ATOM   5033 C C    . PRO B 2 112 ? -13.573 -22.672 44.734 1.000 52.170  ? 113  PRO BBB C    1 
ATOM   5034 O O    . PRO B 2 112 ? -12.591 -21.952 44.705 1.000 55.050  ? 113  PRO BBB O    1 
ATOM   5035 C CB   . PRO B 2 112 ? -13.995 -23.503 47.080 1.000 56.780  ? 113  PRO BBB CB   1 
ATOM   5036 C CG   . PRO B 2 112 ? -15.269 -23.917 47.811 1.000 52.440  ? 113  PRO BBB CG   1 
ATOM   5037 C CD   . PRO B 2 112 ? -16.317 -23.983 46.719 1.000 53.620  ? 113  PRO BBB CD   1 
ATOM   5038 H HA   . PRO B 2 112 ? -14.447 -21.617 46.280 1.000 53.420  ? 113  PRO BBB HA   1 
ATOM   5039 H HB2  . PRO B 2 112 ? -13.533 -24.280 46.702 1.000 56.780  ? 113  PRO BBB HB2  1 
ATOM   5040 H HB3  . PRO B 2 112 ? -13.372 -23.045 47.682 1.000 56.780  ? 113  PRO BBB HB3  1 
ATOM   5041 H HG2  . PRO B 2 112 ? -15.153 -24.785 48.250 1.000 52.440  ? 113  PRO BBB HG2  1 
ATOM   5042 H HG3  . PRO B 2 112 ? -15.507 -23.259 48.497 1.000 52.440  ? 113  PRO BBB HG3  1 
ATOM   5043 H HD2  . PRO B 2 112 ? -16.335 -24.871 46.305 1.000 53.620  ? 113  PRO BBB HD2  1 
ATOM   5044 H HD3  . PRO B 2 112 ? -17.209 -23.798 47.080 1.000 53.620  ? 113  PRO BBB HD3  1 
ATOM   5045 N N    . SER B 2 113 ? -13.912 -23.517 43.754 1.000 51.430  ? 114  SER BBB N    1 
ATOM   5046 C CA   . SER B 2 113 ? -13.099 -23.725 42.522 1.000 60.140  ? 114  SER BBB CA   1 
ATOM   5047 C C    . SER B 2 113 ? -13.198 -22.499 41.585 1.000 62.420  ? 114  SER BBB C    1 
ATOM   5048 O O    . SER B 2 113 ? -12.368 -22.393 40.652 1.000 65.390  ? 114  SER BBB O    1 
ATOM   5049 C CB   . SER B 2 113 ? -13.508 -24.996 41.816 1.000 54.600  ? 114  SER BBB CB   1 
ATOM   5050 O OG   . SER B 2 113 ? -14.843 -24.894 41.327 1.000 59.590  ? 114  SER BBB OG   1 
ATOM   5051 H H    . SER B 2 113 ? -14.771 -24.036 43.871 1.000 51.430  ? 114  SER BBB H    1 
ATOM   5052 H HA   . SER B 2 113 ? -12.147 -23.824 42.794 1.000 60.140  ? 114  SER BBB HA   1 
ATOM   5053 H HB2  . SER B 2 113 ? -12.895 -25.162 41.064 1.000 54.600  ? 114  SER BBB HB2  1 
ATOM   5054 H HB3  . SER B 2 113 ? -13.445 -25.751 42.444 1.000 54.600  ? 114  SER BBB HB3  1 
ATOM   5055 H HG   . SER B 2 113 ? -15.043 -25.618 40.938 0.000 59.590  ? 114  SER BBB HG   1 
ATOM   5056 N N    . GLU B 2 114 ? -14.187 -21.616 41.791 1.000 58.120  ? 115  GLU BBB N    1 
ATOM   5057 C CA   . GLU B 2 114 ? -14.401 -20.383 40.979 1.000 57.820  ? 115  GLU BBB CA   1 
ATOM   5058 C C    . GLU B 2 114 ? -13.502 -19.271 41.514 1.000 51.610  ? 115  GLU BBB C    1 
ATOM   5059 O O    . GLU B 2 114 ? -13.258 -18.315 40.769 1.000 52.920  ? 115  GLU BBB O    1 
ATOM   5060 C CB   . GLU B 2 114 ? -15.874 -19.962 40.952 1.000 58.650  ? 115  GLU BBB CB   1 
ATOM   5061 C CG   . GLU B 2 114 ? -16.731 -20.929 40.150 1.000 63.970  ? 115  GLU BBB CG   1 
ATOM   5062 C CD   . GLU B 2 114 ? -18.186 -20.570 39.869 1.000 64.660  ? 115  GLU BBB CD   1 
ATOM   5063 O OE1  . GLU B 2 114 ? -18.799 -19.831 40.647 1.000 59.930  ? 115  GLU BBB OE1  1 
ATOM   5064 O OE2  . GLU B 2 114 ? -18.710 -21.069 38.867 1.000 70.880  ? 115  GLU BBB OE2  1 
ATOM   5065 H H    . GLU B 2 114 ? -14.818 -21.820 42.553 1.000 58.120  ? 115  GLU BBB H    1 
ATOM   5066 H HA   . GLU B 2 114 ? -14.150 -20.576 40.046 1.000 57.820  ? 115  GLU BBB HA   1 
ATOM   5067 H HB2  . GLU B 2 114 ? -16.203 -19.919 41.874 1.000 58.650  ? 115  GLU BBB HB2  1 
ATOM   5068 H HB3  . GLU B 2 114 ? -15.935 -19.066 40.560 1.000 58.650  ? 115  GLU BBB HB3  1 
ATOM   5069 H HG2  . GLU B 2 114 ? -16.313 -21.073 39.274 1.000 63.970  ? 115  GLU BBB HG2  1 
ATOM   5070 H HG3  . GLU B 2 114 ? -16.750 -21.795 40.611 1.000 63.970  ? 115  GLU BBB HG3  1 
ATOM   5071 N N    . TYR B 2 115 ? -12.990 -19.436 42.733 1.000 53.240  ? 116  TYR BBB N    1 
ATOM   5072 C CA   . TYR B 2 115 ? -11.944 -18.557 43.324 1.000 52.610  ? 116  TYR BBB CA   1 
ATOM   5073 C C    . TYR B 2 115 ? -10.580 -18.993 42.768 1.000 48.240  ? 116  TYR BBB C    1 
ATOM   5074 O O    . TYR B 2 115 ? -10.231 -20.162 42.793 1.000 54.930  ? 116  TYR BBB O    1 
ATOM   5075 C CB   . TYR B 2 115 ? -12.063 -18.517 44.848 1.000 45.910  ? 116  TYR BBB CB   1 
ATOM   5076 C CG   . TYR B 2 115 ? -13.315 -17.830 45.349 1.000 47.430  ? 116  TYR BBB CG   1 
ATOM   5077 C CD1  . TYR B 2 115 ? -14.490 -18.545 45.548 1.000 45.700  ? 116  TYR BBB CD1  1 
ATOM   5078 C CD2  . TYR B 2 115 ? -13.343 -16.463 45.600 1.000 45.350  ? 116  TYR BBB CD2  1 
ATOM   5079 C CE1  . TYR B 2 115 ? -15.646 -17.930 46.004 1.000 46.210  ? 116  TYR BBB CE1  1 
ATOM   5080 C CE2  . TYR B 2 115 ? -14.492 -15.836 46.058 1.000 44.660  ? 116  TYR BBB CE2  1 
ATOM   5081 C CZ   . TYR B 2 115 ? -15.647 -16.574 46.282 1.000 44.370  ? 116  TYR BBB CZ   1 
ATOM   5082 O OH   . TYR B 2 115 ? -16.794 -15.977 46.734 1.000 38.620  ? 116  TYR BBB OH   1 
ATOM   5083 H H    . TYR B 2 115 ? -13.346 -20.211 43.275 1.000 53.240  ? 116  TYR BBB H    1 
ATOM   5084 H HA   . TYR B 2 115 ? -12.122 -17.623 43.046 1.000 52.610  ? 116  TYR BBB HA   1 
ATOM   5085 H HB2  . TYR B 2 115 ? -12.042 -19.437 45.185 1.000 45.910  ? 116  TYR BBB HB2  1 
ATOM   5086 H HB3  . TYR B 2 115 ? -11.276 -18.058 45.208 1.000 45.910  ? 116  TYR BBB HB3  1 
ATOM   5087 H HD1  . TYR B 2 115 ? -14.504 -19.470 45.367 1.000 45.700  ? 116  TYR BBB HD1  1 
ATOM   5088 H HD2  . TYR B 2 115 ? -12.565 -15.950 45.456 1.000 45.350  ? 116  TYR BBB HD2  1 
ATOM   5089 H HE1  . TYR B 2 115 ? -16.432 -18.435 46.132 1.000 46.210  ? 116  TYR BBB HE1  1 
ATOM   5090 H HE2  . TYR B 2 115 ? -14.480 -14.911 46.243 1.000 44.660  ? 116  TYR BBB HE2  1 
ATOM   5091 H HH   . TYR B 2 115 ? -17.042 -16.338 47.472 0.000 38.620  ? 116  TYR BBB HH   1 
ATOM   5092 N N    . THR B 2 116 ? -9.855  -18.026 42.231 1.000 44.990  ? 117  THR BBB N    1 
ATOM   5093 C CA   . THR B 2 116 ? -8.763  -18.200 41.260 1.000 40.750  ? 117  THR BBB CA   1 
ATOM   5094 C C    . THR B 2 116 ? -7.516  -17.469 41.758 1.000 39.150  ? 117  THR BBB C    1 
ATOM   5095 O O    . THR B 2 116 ? -6.429  -17.968 41.483 1.000 45.930  ? 117  THR BBB O    1 
ATOM   5096 C CB   . THR B 2 116 ? -9.223  -17.658 39.901 1.000 47.240  ? 117  THR BBB CB   1 
ATOM   5097 O OG1  . THR B 2 116 ? -10.164 -18.566 39.326 1.000 49.720  ? 117  THR BBB OG1  1 
ATOM   5098 C CG2  . THR B 2 116 ? -8.088  -17.451 38.929 1.000 49.240  ? 117  THR BBB CG2  1 
ATOM   5099 H H    . THR B 2 116 ? -10.099 -17.095 42.536 1.000 44.990  ? 117  THR BBB H    1 
ATOM   5100 H HA   . THR B 2 116 ? -8.559  -19.162 41.199 1.000 40.750  ? 117  THR BBB HA   1 
ATOM   5101 H HB   . THR B 2 116 ? -9.673  -16.792 40.049 1.000 47.240  ? 117  THR BBB HB   1 
ATOM   5102 H HG1  . THR B 2 116 ? -10.422 -18.271 38.574 0.000 49.720  ? 117  THR BBB HG1  1 
ATOM   5103 H HG21 . THR B 2 116 ? -7.454  -16.811 39.300 1.000 49.240  ? 117  THR BBB HG21 1 
ATOM   5104 H HG22 . THR B 2 116 ? -8.438  -17.106 38.088 1.000 49.240  ? 117  THR BBB HG22 1 
ATOM   5105 H HG23 . THR B 2 116 ? -7.637  -18.299 38.769 1.000 49.240  ? 117  THR BBB HG23 1 
ATOM   5106 N N    . PHE B 2 117 ? -7.646  -16.299 42.382 1.000 38.440  ? 118  PHE BBB N    1 
ATOM   5107 C CA   . PHE B 2 117 ? -6.517  -15.494 42.936 1.000 42.610  ? 118  PHE BBB CA   1 
ATOM   5108 C C    . PHE B 2 117 ? -6.622  -15.479 44.471 1.000 43.440  ? 118  PHE BBB C    1 
ATOM   5109 O O    . PHE B 2 117 ? -7.731  -15.366 44.989 1.000 45.440  ? 118  PHE BBB O    1 
ATOM   5110 C CB   . PHE B 2 117 ? -6.508  -14.067 42.368 1.000 43.960  ? 118  PHE BBB CB   1 
ATOM   5111 C CG   . PHE B 2 117 ? -6.682  -14.006 40.868 1.000 52.950  ? 118  PHE BBB CG   1 
ATOM   5112 C CD1  . PHE B 2 117 ? -5.629  -14.302 40.019 1.000 48.420  ? 118  PHE BBB CD1  1 
ATOM   5113 C CD2  . PHE B 2 117 ? -7.907  -13.681 40.300 1.000 54.150  ? 118  PHE BBB CD2  1 
ATOM   5114 C CE1  . PHE B 2 117 ? -5.790  -14.260 38.646 1.000 47.910  ? 118  PHE BBB CE1  1 
ATOM   5115 C CE2  . PHE B 2 117 ? -8.062  -13.631 38.922 1.000 54.700  ? 118  PHE BBB CE2  1 
ATOM   5116 C CZ   . PHE B 2 117 ? -7.004  -13.925 38.096 1.000 51.640  ? 118  PHE BBB CZ   1 
ATOM   5117 H H    . PHE B 2 117 ? -8.590  -15.952 42.474 1.000 38.440  ? 118  PHE BBB H    1 
ATOM   5118 H HA   . PHE B 2 117 ? -5.664  -15.928 42.680 1.000 42.610  ? 118  PHE BBB HA   1 
ATOM   5119 H HB2  . PHE B 2 117 ? -7.226  -13.557 42.799 1.000 43.960  ? 118  PHE BBB HB2  1 
ATOM   5120 H HB3  . PHE B 2 117 ? -5.661  -13.641 42.614 1.000 43.960  ? 118  PHE BBB HB3  1 
ATOM   5121 H HD1  . PHE B 2 117 ? -4.792  -14.545 40.382 1.000 48.420  ? 118  PHE BBB HD1  1 
ATOM   5122 H HD2  . PHE B 2 117 ? -8.642  -13.492 40.862 1.000 54.150  ? 118  PHE BBB HD2  1 
ATOM   5123 H HE1  . PHE B 2 117 ? -5.061  -14.465 38.082 1.000 47.910  ? 118  PHE BBB HE1  1 
ATOM   5124 H HE2  . PHE B 2 117 ? -8.899  -13.400 38.551 1.000 54.700  ? 118  PHE BBB HE2  1 
ATOM   5125 H HZ   . PHE B 2 117 ? -7.106  -13.899 37.158 1.000 51.640  ? 118  PHE BBB HZ   1 
ATOM   5126 N N    . TRP B 2 118 ? -5.489  -15.583 45.169 1.000 46.470  ? 119  TRP BBB N    1 
ATOM   5127 C CA   . TRP B 2 118 ? -5.382  -15.864 46.632 1.000 43.680  ? 119  TRP BBB CA   1 
ATOM   5128 C C    . TRP B 2 118 ? -4.307  -14.978 47.249 1.000 44.860  ? 119  TRP BBB C    1 
ATOM   5129 O O    . TRP B 2 118 ? -3.295  -14.748 46.575 1.000 53.060  ? 119  TRP BBB O    1 
ATOM   5130 C CB   . TRP B 2 118 ? -5.052  -17.335 46.855 1.000 43.360  ? 119  TRP BBB CB   1 
ATOM   5131 C CG   . TRP B 2 118 ? -6.104  -18.244 46.320 1.000 45.770  ? 119  TRP BBB CG   1 
ATOM   5132 C CD1  . TRP B 2 118 ? -6.237  -18.710 45.045 1.000 45.160  ? 119  TRP BBB CD1  1 
ATOM   5133 C CD2  . TRP B 2 118 ? -7.219  -18.753 47.064 1.000 47.580  ? 119  TRP BBB CD2  1 
ATOM   5134 N NE1  . TRP B 2 118 ? -7.354  -19.501 44.952 1.000 47.280  ? 119  TRP BBB NE1  1 
ATOM   5135 C CE2  . TRP B 2 118 ? -7.976  -19.546 46.174 1.000 46.550  ? 119  TRP BBB CE2  1 
ATOM   5136 C CE3  . TRP B 2 118 ? -7.636  -18.622 48.395 1.000 48.340  ? 119  TRP BBB CE3  1 
ATOM   5137 C CZ2  . TRP B 2 118 ? -9.140  -20.203 46.571 1.000 51.860  ? 119  TRP BBB CZ2  1 
ATOM   5138 C CZ3  . TRP B 2 118 ? -8.786  -19.275 48.781 1.000 51.530  ? 119  TRP BBB CZ3  1 
ATOM   5139 C CH2  . TRP B 2 118 ? -9.517  -20.066 47.887 1.000 49.740  ? 119  TRP BBB CH2  1 
ATOM   5140 H H    . TRP B 2 118 ? -4.645  -15.455 44.629 1.000 46.470  ? 119  TRP BBB H    1 
ATOM   5141 H HA   . TRP B 2 118 ? -6.250  -15.650 47.048 1.000 43.680  ? 119  TRP BBB HA   1 
ATOM   5142 H HB2  . TRP B 2 118 ? -4.197  -17.527 46.419 1.000 43.360  ? 119  TRP BBB HB2  1 
ATOM   5143 H HB3  . TRP B 2 118 ? -4.946  -17.483 47.817 1.000 43.360  ? 119  TRP BBB HB3  1 
ATOM   5144 H HD1  . TRP B 2 118 ? -5.658  -18.504 44.327 1.000 45.160  ? 119  TRP BBB HD1  1 
ATOM   5145 H HE1  . TRP B 2 118 ? -7.631  -19.904 44.224 1.000 47.280  ? 119  TRP BBB HE1  1 
ATOM   5146 H HE3  . TRP B 2 118 ? -7.141  -18.096 49.003 1.000 48.340  ? 119  TRP BBB HE3  1 
ATOM   5147 H HZ2  . TRP B 2 118 ? -9.646  -20.718 45.965 1.000 51.860  ? 119  TRP BBB HZ2  1 
ATOM   5148 H HZ3  . TRP B 2 118 ? -9.085  -19.200 49.673 1.000 51.530  ? 119  TRP BBB HZ3  1 
ATOM   5149 H HH2  . TRP B 2 118 ? -10.298 -20.497 48.187 1.000 49.740  ? 119  TRP BBB HH2  1 
ATOM   5150 N N    . GLY B 2 119 ? -4.545  -14.463 48.453 1.000 44.660  ? 120  GLY BBB N    1 
ATOM   5151 C CA   . GLY B 2 119 ? -3.581  -13.623 49.180 1.000 45.170  ? 120  GLY BBB CA   1 
ATOM   5152 C C    . GLY B 2 119 ? -2.614  -14.520 49.926 1.000 45.680  ? 120  GLY BBB C    1 
ATOM   5153 O O    . GLY B 2 119 ? -2.646  -15.742 49.674 1.000 40.070  ? 120  GLY BBB O    1 
ATOM   5154 H H    . GLY B 2 119 ? -5.438  -14.668 48.878 1.000 44.660  ? 120  GLY BBB H    1 
ATOM   5155 H HA2  . GLY B 2 119 ? -3.101  -13.048 48.533 1.000 45.170  ? 120  GLY BBB HA2  1 
ATOM   5156 H HA3  . GLY B 2 119 ? -4.073  -13.036 49.807 1.000 45.170  ? 120  GLY BBB HA3  1 
ATOM   5157 N N    . GLN B 2 120 ? -1.787  -13.945 50.795 1.000 44.860  ? 121  GLN BBB N    1 
ATOM   5158 C CA   . GLN B 2 120 ? -0.683  -14.677 51.471 1.000 59.970  ? 121  GLN BBB CA   1 
ATOM   5159 C C    . GLN B 2 120 ? -1.201  -15.259 52.802 1.000 57.280  ? 121  GLN BBB C    1 
ATOM   5160 O O    . GLN B 2 120 ? -0.653  -16.283 53.241 1.000 69.210  ? 121  GLN BBB O    1 
ATOM   5161 C CB   . GLN B 2 120 ? 0.574   -13.795 51.542 1.000 69.090  ? 121  GLN BBB CB   1 
ATOM   5162 C CG   . GLN B 2 120 ? 0.601   -12.765 52.670 1.000 78.030  ? 121  GLN BBB CG   1 
ATOM   5163 C CD   . GLN B 2 120 ? -0.202  -11.516 52.391 1.000 86.330  ? 121  GLN BBB CD   1 
ATOM   5164 O OE1  . GLN B 2 120 ? -0.674  -11.297 51.274 1.000 108.400 ? 121  GLN BBB OE1  1 
ATOM   5165 N NE2  . GLN B 2 120 ? -0.390  -10.696 53.419 1.000 80.700  ? 121  GLN BBB NE2  1 
ATOM   5166 H H    . GLN B 2 120 ? -1.925  -12.965 50.998 1.000 44.860  ? 121  GLN BBB H    1 
ATOM   5167 H HA   . GLN B 2 120 ? -0.398  -15.419 50.889 1.000 59.970  ? 121  GLN BBB HA   1 
ATOM   5168 H HB2  . GLN B 2 120 ? 1.357   -14.376 51.644 1.000 69.090  ? 121  GLN BBB HB2  1 
ATOM   5169 H HB3  . GLN B 2 120 ? 0.667   -13.315 50.693 1.000 69.090  ? 121  GLN BBB HB3  1 
ATOM   5170 H HG2  . GLN B 2 120 ? 0.250   -13.174 53.489 1.000 78.030  ? 121  GLN BBB HG2  1 
ATOM   5171 H HG3  . GLN B 2 120 ? 1.529   -12.497 52.840 1.000 78.030  ? 121  GLN BBB HG3  1 
ATOM   5172 H HE21 . GLN B 2 120 ? -0.853  -9.951  53.311 0.000 80.700  ? 121  GLN BBB HE21 1 
ATOM   5173 H HE22 . GLN B 2 120 ? -0.052  -10.895 54.211 0.000 80.700  ? 121  GLN BBB HE22 1 
ATOM   5174 N N    . GLY B 2 121 ? -2.264  -14.692 53.385 1.000 56.570  ? 122  GLY BBB N    1 
ATOM   5175 C CA   . GLY B 2 121 ? -2.901  -15.175 54.627 1.000 49.110  ? 122  GLY BBB CA   1 
ATOM   5176 C C    . GLY B 2 121 ? -2.621  -14.223 55.765 1.000 49.940  ? 122  GLY BBB C    1 
ATOM   5177 O O    . GLY B 2 121 ? -1.596  -13.578 55.705 1.000 54.340  ? 122  GLY BBB O    1 
ATOM   5178 H H    . GLY B 2 121 ? -2.640  -13.876 52.924 1.000 56.570  ? 122  GLY BBB H    1 
ATOM   5179 H HA2  . GLY B 2 121 ? -3.877  -15.253 54.480 1.000 49.110  ? 122  GLY BBB HA2  1 
ATOM   5180 H HA3  . GLY B 2 121 ? -2.549  -16.075 54.842 1.000 49.110  ? 122  GLY BBB HA3  1 
ATOM   5181 N N    . THR B 2 122 ? -3.532  -14.077 56.732 1.000 57.010  ? 123  THR BBB N    1 
ATOM   5182 C CA   . THR B 2 122 ? -3.306  -13.295 57.985 1.000 54.540  ? 123  THR BBB CA   1 
ATOM   5183 C C    . THR B 2 122 ? -3.817  -14.166 59.127 1.000 53.870  ? 123  THR BBB C    1 
ATOM   5184 O O    . THR B 2 122 ? -4.913  -14.777 58.927 1.000 46.690  ? 123  THR BBB O    1 
ATOM   5185 C CB   . THR B 2 122 ? -3.913  -11.885 57.927 1.000 49.630  ? 123  THR BBB CB   1 
ATOM   5186 O OG1  . THR B 2 122 ? -3.260  -11.086 58.903 1.000 54.980  ? 123  THR BBB OG1  1 
ATOM   5187 C CG2  . THR B 2 122 ? -5.395  -11.816 58.200 1.000 56.620  ? 123  THR BBB CG2  1 
ATOM   5188 H H    . THR B 2 122 ? -4.423  -14.531 56.589 1.000 57.010  ? 123  THR BBB H    1 
ATOM   5189 H HA   . THR B 2 122 ? -2.337  -13.146 58.081 1.000 54.540  ? 123  THR BBB HA   1 
ATOM   5190 H HB   . THR B 2 122 ? -3.756  -11.518 57.024 1.000 49.630  ? 123  THR BBB HB   1 
ATOM   5191 H HG1  . THR B 2 122 ? -3.580  -10.301 58.889 0.000 54.980  ? 123  THR BBB HG1  1 
ATOM   5192 H HG21 . THR B 2 122 ? -5.873  -12.351 57.541 1.000 56.620  ? 123  THR BBB HG21 1 
ATOM   5193 H HG22 . THR B 2 122 ? -5.695  -10.891 58.142 1.000 56.620  ? 123  THR BBB HG22 1 
ATOM   5194 H HG23 . THR B 2 122 ? -5.579  -12.161 59.092 1.000 56.620  ? 123  THR BBB HG23 1 
ATOM   5195 N N    . GLN B 2 123 ? -3.010  -14.296 60.199 1.000 51.350  ? 124  GLN BBB N    1 
ATOM   5196 C CA   . GLN B 2 123 ? -3.323  -15.148 61.384 1.000 53.200  ? 124  GLN BBB CA   1 
ATOM   5197 C C    . GLN B 2 123 ? -4.262  -14.384 62.316 1.000 47.700  ? 124  GLN BBB C    1 
ATOM   5198 O O    . GLN B 2 123 ? -3.973  -13.232 62.669 1.000 43.490  ? 124  GLN BBB O    1 
ATOM   5199 C CB   . GLN B 2 123 ? -2.070  -15.585 62.171 1.000 52.490  ? 124  GLN BBB CB   1 
ATOM   5200 C CG   . GLN B 2 123 ? -2.370  -16.478 63.382 1.000 48.850  ? 124  GLN BBB CG   1 
ATOM   5201 C CD   . GLN B 2 123 ? -2.921  -17.850 63.063 1.000 53.260  ? 124  GLN BBB CD   1 
ATOM   5202 O OE1  . GLN B 2 123 ? -2.531  -18.483 62.090 1.000 61.790  ? 124  GLN BBB OE1  1 
ATOM   5203 N NE2  . GLN B 2 123 ? -3.821  -18.355 63.891 1.000 51.440  ? 124  GLN BBB NE2  1 
ATOM   5204 H H    . GLN B 2 123 ? -2.144  -13.777 60.181 1.000 51.350  ? 124  GLN BBB H    1 
ATOM   5205 H HA   . GLN B 2 123 ? -3.779  -15.963 61.071 1.000 53.200  ? 124  GLN BBB HA   1 
ATOM   5206 H HB2  . GLN B 2 123 ? -1.472  -16.067 61.562 1.000 52.490  ? 124  GLN BBB HB2  1 
ATOM   5207 H HB3  . GLN B 2 123 ? -1.599  -14.782 62.479 1.000 52.490  ? 124  GLN BBB HB3  1 
ATOM   5208 H HG2  . GLN B 2 123 ? -1.547  -16.608 63.899 1.000 48.850  ? 124  GLN BBB HG2  1 
ATOM   5209 H HG3  . GLN B 2 123 ? -3.023  -16.029 63.960 1.000 48.850  ? 124  GLN BBB HG3  1 
ATOM   5210 H HE21 . GLN B 2 123 ? -4.165  -19.154 63.736 0.000 51.440  ? 124  GLN BBB HE21 1 
ATOM   5211 H HE22 . GLN B 2 123 ? -4.079  -17.893 64.599 0.000 51.440  ? 124  GLN BBB HE22 1 
ATOM   5212 N N    . VAL B 2 124 ? -5.334  -15.043 62.730 1.000 49.990  ? 125  VAL BBB N    1 
ATOM   5213 C CA   . VAL B 2 124 ? -6.167  -14.570 63.867 1.000 53.060  ? 125  VAL BBB CA   1 
ATOM   5214 C C    . VAL B 2 124 ? -6.158  -15.654 64.948 1.000 52.780  ? 125  VAL BBB C    1 
ATOM   5215 O O    . VAL B 2 124 ? -6.598  -16.786 64.663 1.000 49.990  ? 125  VAL BBB O    1 
ATOM   5216 C CB   . VAL B 2 124 ? -7.585  -14.222 63.389 1.000 57.440  ? 125  VAL BBB CB   1 
ATOM   5217 C CG1  . VAL B 2 124 ? -8.457  -13.745 64.538 1.000 59.300  ? 125  VAL BBB CG1  1 
ATOM   5218 C CG2  . VAL B 2 124 ? -7.547  -13.173 62.276 1.000 58.030  ? 125  VAL BBB CG2  1 
ATOM   5219 H H    . VAL B 2 124 ? -5.590  -15.896 62.253 1.000 49.990  ? 125  VAL BBB H    1 
ATOM   5220 H HA   . VAL B 2 124 ? -5.762  -13.762 64.229 1.000 53.060  ? 125  VAL BBB HA   1 
ATOM   5221 H HB   . VAL B 2 124 ? -7.980  -15.048 63.016 1.000 57.440  ? 125  VAL BBB HB   1 
ATOM   5222 H HG11 . VAL B 2 124 ? -8.521  -14.446 65.210 1.000 59.300  ? 125  VAL BBB HG11 1 
ATOM   5223 H HG12 . VAL B 2 124 ? -9.346  -13.532 64.205 1.000 59.300  ? 125  VAL BBB HG12 1 
ATOM   5224 H HG13 . VAL B 2 124 ? -8.063  -12.950 64.937 1.000 59.300  ? 125  VAL BBB HG13 1 
ATOM   5225 H HG21 . VAL B 2 124 ? -7.122  -12.363 62.607 1.000 58.030  ? 125  VAL BBB HG21 1 
ATOM   5226 H HG22 . VAL B 2 124 ? -8.455  -12.970 61.990 1.000 58.030  ? 125  VAL BBB HG22 1 
ATOM   5227 H HG23 . VAL B 2 124 ? -7.040  -13.519 61.521 1.000 58.030  ? 125  VAL BBB HG23 1 
ATOM   5228 N N    . THR B 2 125 ? -5.628  -15.318 66.123 1.000 59.210  ? 126  THR BBB N    1 
ATOM   5229 C CA   . THR B 2 125 ? -5.651  -16.186 67.336 1.000 66.650  ? 126  THR BBB CA   1 
ATOM   5230 C C    . THR B 2 125 ? -6.586  -15.567 68.394 1.000 60.910  ? 126  THR BBB C    1 
ATOM   5231 O O    . THR B 2 125 ? -6.374  -14.365 68.784 1.000 45.960  ? 126  THR BBB O    1 
ATOM   5232 C CB   . THR B 2 125 ? -4.240  -16.446 67.876 1.000 66.040  ? 126  THR BBB CB   1 
ATOM   5233 O OG1  . THR B 2 125 ? -3.304  -16.527 66.794 1.000 60.110  ? 126  THR BBB OG1  1 
ATOM   5234 C CG2  . THR B 2 125 ? -4.208  -17.709 68.712 1.000 61.690  ? 126  THR BBB CG2  1 
ATOM   5235 H H    . THR B 2 125 ? -5.186  -14.411 66.175 1.000 59.210  ? 126  THR BBB H    1 
ATOM   5236 H HA   . THR B 2 125 ? -6.011  -17.065 67.075 1.000 66.650  ? 126  THR BBB HA   1 
ATOM   5237 H HB   . THR B 2 125 ? -3.972  -15.672 68.427 1.000 66.040  ? 126  THR BBB HB   1 
ATOM   5238 H HG1  . THR B 2 125 ? -2.527  -16.671 67.100 0.000 60.110  ? 126  THR BBB HG1  1 
ATOM   5239 H HG21 . THR B 2 125 ? -4.819  -17.617 69.465 1.000 61.690  ? 126  THR BBB HG21 1 
ATOM   5240 H HG22 . THR B 2 125 ? -3.305  -17.856 69.046 1.000 61.690  ? 126  THR BBB HG22 1 
ATOM   5241 H HG23 . THR B 2 125 ? -4.479  -18.469 68.166 1.000 61.690  ? 126  THR BBB HG23 1 
ATOM   5242 N N    . VAL B 2 126 ? -7.612  -16.335 68.779 1.000 53.040  ? 127  VAL BBB N    1 
ATOM   5243 C CA   . VAL B 2 126 ? -8.647  -15.959 69.783 1.000 64.630  ? 127  VAL BBB CA   1 
ATOM   5244 C C    . VAL B 2 126 ? -8.262  -16.685 71.077 1.000 71.170  ? 127  VAL BBB C    1 
ATOM   5245 O O    . VAL B 2 126 ? -8.589  -17.892 71.162 1.000 67.430  ? 127  VAL BBB O    1 
ATOM   5246 C CB   . VAL B 2 126 ? -10.063 -16.352 69.307 1.000 67.250  ? 127  VAL BBB CB   1 
ATOM   5247 C CG1  . VAL B 2 126 ? -11.143 -15.952 70.301 1.000 72.350  ? 127  VAL BBB CG1  1 
ATOM   5248 C CG2  . VAL B 2 126 ? -10.389 -15.766 67.943 1.000 77.170  ? 127  VAL BBB CG2  1 
ATOM   5249 H H    . VAL B 2 126 ? -7.663  -17.240 68.334 1.000 53.040  ? 127  VAL BBB H    1 
ATOM   5250 H HA   . VAL B 2 126 ? -8.607  -14.996 69.920 1.000 64.630  ? 127  VAL BBB HA   1 
ATOM   5251 H HB   . VAL B 2 126 ? -10.080 -17.337 69.219 1.000 67.250  ? 127  VAL BBB HB   1 
ATOM   5252 H HG11 . VAL B 2 126 ? -10.980 -16.393 71.153 1.000 72.350  ? 127  VAL BBB HG11 1 
ATOM   5253 H HG12 . VAL B 2 126 ? -12.014 -16.219 69.959 1.000 72.350  ? 127  VAL BBB HG12 1 
ATOM   5254 H HG13 . VAL B 2 126 ? -11.127 -14.987 70.428 1.000 72.350  ? 127  VAL BBB HG13 1 
ATOM   5255 H HG21 . VAL B 2 126 ? -10.342 -14.795 67.987 1.000 77.170  ? 127  VAL BBB HG21 1 
ATOM   5256 H HG22 . VAL B 2 126 ? -11.286 -16.036 67.679 1.000 77.170  ? 127  VAL BBB HG22 1 
ATOM   5257 H HG23 . VAL B 2 126 ? -9.748  -16.092 67.288 1.000 77.170  ? 127  VAL BBB HG23 1 
ATOM   5258 N N    . SER B 2 127 ? -7.566  -16.008 72.010 1.000 78.610  ? 128  SER BBB N    1 
ATOM   5259 C CA   . SER B 2 127 ? -7.000  -16.606 73.258 1.000 85.640  ? 128  SER BBB CA   1 
ATOM   5260 C C    . SER B 2 127 ? -6.976  -15.595 74.427 1.000 91.930  ? 128  SER BBB C    1 
ATOM   5261 O O    . SER B 2 127 ? -7.744  -14.616 74.375 1.000 94.630  ? 128  SER BBB O    1 
ATOM   5262 C CB   . SER B 2 127 ? -5.627  -17.177 72.974 1.000 90.240  ? 128  SER BBB CB   1 
ATOM   5263 O OG   . SER B 2 127 ? -5.396  -18.371 73.713 1.000 86.490  ? 128  SER BBB OG   1 
ATOM   5264 H H    . SER B 2 127 ? -7.430  -15.024 71.830 1.000 78.610  ? 128  SER BBB H    1 
ATOM   5265 H HA   . SER B 2 127 ? -7.588  -17.360 73.533 1.000 85.640  ? 128  SER BBB HA   1 
ATOM   5266 H HB2  . SER B 2 127 ? -5.549  -17.373 72.013 1.000 90.240  ? 128  SER BBB HB2  1 
ATOM   5267 H HB3  . SER B 2 127 ? -4.942  -16.512 73.214 1.000 90.240  ? 128  SER BBB HB3  1 
ATOM   5268 H HG   . SER B 2 127 ? -4.622  -18.657 73.527 0.000 86.490  ? 128  SER BBB HG   1 
ATOM   5269 N N    . SER B 2 128 ? -6.152  -15.843 75.463 1.000 105.890 ? 129  SER BBB N    1 
ATOM   5270 C CA   . SER B 2 128 ? -5.883  -14.938 76.623 1.000 97.000  ? 129  SER BBB CA   1 
ATOM   5271 C C    . SER B 2 128 ? -4.381  -14.634 76.741 1.000 99.110  ? 129  SER BBB C    1 
ATOM   5272 O O    . SER B 2 128 ? -3.997  -13.577 77.242 1.000 95.060  ? 129  SER BBB O    1 
ATOM   5273 C CB   . SER B 2 128 ? -6.415  -15.525 77.894 1.000 81.310  ? 129  SER BBB CB   1 
ATOM   5274 O OG   . SER B 2 128 ? -7.792  -15.806 77.755 1.000 69.020  ? 129  SER BBB OG   1 
ATOM   5275 H H    . SER B 2 128 ? -5.687  -16.738 75.419 1.000 105.890 ? 129  SER BBB H    1 
ATOM   5276 H HA   . SER B 2 128 ? -6.356  -14.078 76.459 1.000 97.000  ? 129  SER BBB HA   1 
ATOM   5277 H HB2  . SER B 2 128 ? -5.924  -16.352 78.101 1.000 81.310  ? 129  SER BBB HB2  1 
ATOM   5278 H HB3  . SER B 2 128 ? -6.277  -14.887 78.630 1.000 81.310  ? 129  SER BBB HB3  1 
ATOM   5279 H HG   . SER B 2 128 ? -8.074  -16.136 78.481 0.000 69.020  ? 129  SER BBB HG   1 
HETATM 5280 S S    . SO4 C 3 .   ? -27.501 -5.341  39.261 1.000 93.330  ? 1501 SO4 AAA S    1 
HETATM 5281 O O1   . SO4 C 3 .   ? -26.119 -5.642  39.531 1.000 77.330  ? 1501 SO4 AAA O1   1 
HETATM 5282 O O2   . SO4 C 3 .   ? -27.756 -5.310  37.825 1.000 96.140  ? 1501 SO4 AAA O2   1 
HETATM 5283 O O3   . SO4 C 3 .   ? -28.309 -6.366  39.867 1.000 101.860 ? 1501 SO4 AAA O3   1 
HETATM 5284 O O4   . SO4 C 3 .   ? -27.836 -4.054  39.827 1.000 83.890  ? 1501 SO4 AAA O4   1 
HETATM 5285 O O    . HOH D 4 .   ? -16.691 -9.082  22.221 1.000 319.910 ? 1601 HOH AAA O    1 
HETATM 5286 O O    . HOH D 4 .   ? -21.950 5.014   -8.010 1.000 41.370  ? 1602 HOH AAA O    1 
HETATM 5287 O O    . HOH D 4 .   ? -34.746 -6.457  -3.141 1.000 60.970  ? 1603 HOH AAA O    1 
HETATM 5288 O O    . HOH D 4 .   ? -33.991 6.984   26.529 1.000 51.030  ? 1604 HOH AAA O    1 
HETATM 5289 O O    . HOH D 4 .   ? -24.240 2.987   -9.843 1.000 76.000  ? 1605 HOH AAA O    1 
HETATM 5290 O O    . HOH D 4 .   ? -39.829 14.833  23.571 1.000 65.070  ? 1606 HOH AAA O    1 
HETATM 5291 O O    . HOH D 4 .   ? -13.210 7.250   28.674 1.000 60.760  ? 1607 HOH AAA O    1 
HETATM 5292 O O    . HOH D 4 .   ? -33.287 -1.928  -0.043 1.000 66.690  ? 1608 HOH AAA O    1 
HETATM 5293 O O    . HOH D 4 .   ? -24.797 -7.658  43.996 1.000 48.560  ? 1609 HOH AAA O    1 
HETATM 5294 O O    . HOH D 4 .   ? -17.455 -9.433  9.705  1.000 38.170  ? 1610 HOH AAA O    1 
HETATM 5295 O O    . HOH D 4 .   ? -44.842 5.483   20.681 1.000 73.900  ? 1611 HOH AAA O    1 
HETATM 5296 O O    . HOH D 4 .   ? -26.508 0.952   39.516 1.000 57.750  ? 1612 HOH AAA O    1 
HETATM 5297 O O    . HOH D 4 .   ? -25.959 -6.882  36.842 1.000 35.180  ? 1613 HOH AAA O    1 
HETATM 5298 O O    . HOH D 4 .   ? -36.729 10.589  21.255 1.000 53.030  ? 1614 HOH AAA O    1 
HETATM 5299 O O    . HOH D 4 .   ? -26.515 -7.911  32.474 1.000 62.180  ? 1615 HOH AAA O    1 
HETATM 5300 O O    . HOH D 4 .   ? -19.171 -8.713  7.768  1.000 45.670  ? 1616 HOH AAA O    1 
HETATM 5301 O O    . HOH D 4 .   ? -16.073 1.472   35.178 1.000 46.250  ? 1617 HOH AAA O    1 
HETATM 5302 O O    . HOH D 4 .   ? -25.957 13.973  22.814 1.000 62.330  ? 1618 HOH AAA O    1 
HETATM 5303 O O    . HOH D 4 .   ? -37.787 5.933   -2.686 1.000 70.460  ? 1619 HOH AAA O    1 
HETATM 5304 O O    . HOH D 4 .   ? -2.023  -12.661 23.019 1.000 70.680  ? 1620 HOH AAA O    1 
HETATM 5305 O O    . HOH D 4 .   ? -32.880 0.456   6.850  1.000 37.180  ? 1621 HOH AAA O    1 
HETATM 5306 O O    . HOH D 4 .   ? -45.739 0.789   11.009 1.000 74.110  ? 1622 HOH AAA O    1 
HETATM 5307 O O    . HOH D 4 .   ? -39.335 -4.995  28.526 1.000 69.200  ? 1623 HOH AAA O    1 
HETATM 5308 O O    . HOH D 4 .   ? -39.339 -10.545 19.648 1.000 49.300  ? 1624 HOH AAA O    1 
HETATM 5309 O O    . HOH D 4 .   ? -37.402 -7.579  13.005 1.000 56.450  ? 1625 HOH AAA O    1 
HETATM 5310 O O    . HOH D 4 .   ? -26.974 -9.083  40.429 1.000 51.340  ? 1626 HOH AAA O    1 
HETATM 5311 O O    . HOH D 4 .   ? -32.524 -1.810  4.957  1.000 44.380  ? 1627 HOH AAA O    1 
HETATM 5312 O O    . HOH D 4 .   ? -20.578 0.481   35.450 1.000 47.030  ? 1628 HOH AAA O    1 
HETATM 5313 O O    . HOH D 4 .   ? -44.069 2.800   15.693 1.000 63.060  ? 1629 HOH AAA O    1 
HETATM 5314 O O    . HOH D 4 .   ? -35.115 3.269   5.545  1.000 54.510  ? 1630 HOH AAA O    1 
HETATM 5315 O O    . HOH D 4 .   ? -9.374  -1.681  16.743 1.000 47.130  ? 1631 HOH AAA O    1 
HETATM 5316 O O    . HOH D 4 .   ? -24.838 -4.705  -2.542 1.000 57.800  ? 1632 HOH AAA O    1 
HETATM 5317 O O    . HOH D 4 .   ? -32.258 0.280   9.465  1.000 46.980  ? 1633 HOH AAA O    1 
HETATM 5318 O O    . HOH D 4 .   ? -6.423  4.968   22.886 1.000 73.630  ? 1634 HOH AAA O    1 
HETATM 5319 O O    . HOH D 4 .   ? -20.124 -14.733 22.397 1.000 55.330  ? 1635 HOH AAA O    1 
HETATM 5320 O O    . HOH D 4 .   ? -39.639 5.713   8.425  1.000 61.140  ? 1636 HOH AAA O    1 
HETATM 5321 O O    . HOH D 4 .   ? -44.120 2.622   10.666 1.000 60.030  ? 1637 HOH AAA O    1 
HETATM 5322 O O    . HOH D 4 .   ? -39.166 1.165   6.368  1.000 56.080  ? 1638 HOH AAA O    1 
HETATM 5323 O O    . HOH D 4 .   ? -41.922 -10.869 21.602 1.000 64.300  ? 1639 HOH AAA O    1 
HETATM 5324 O O    . HOH D 4 .   ? -21.388 -2.548  35.583 1.000 35.780  ? 1640 HOH AAA O    1 
HETATM 5325 O O    . HOH D 4 .   ? -31.968 -9.018  29.821 1.000 48.920  ? 1641 HOH AAA O    1 
HETATM 5326 O O    . HOH D 4 .   ? -16.803 11.954  11.048 1.000 48.360  ? 1642 HOH AAA O    1 
HETATM 5327 O O    . HOH D 4 .   ? -14.739 5.019   23.848 1.000 44.740  ? 1643 HOH AAA O    1 
HETATM 5328 O O    . HOH D 4 .   ? -15.439 -4.775  -0.300 1.000 51.030  ? 1644 HOH AAA O    1 
HETATM 5329 O O    . HOH D 4 .   ? -11.624 -3.127  3.989  1.000 51.950  ? 1645 HOH AAA O    1 
HETATM 5330 O O    . HOH D 4 .   ? -31.332 -11.541 28.014 1.000 57.320  ? 1646 HOH AAA O    1 
HETATM 5331 O O    . HOH D 4 .   ? -25.779 4.872   25.886 1.000 244.900 ? 1647 HOH AAA O    1 
HETATM 5332 O O    . HOH D 4 .   ? -20.368 3.093   31.655 1.000 46.940  ? 1648 HOH AAA O    1 
HETATM 5333 O O    . HOH D 4 .   ? -40.830 -1.377  18.332 1.000 59.790  ? 1649 HOH AAA O    1 
HETATM 5334 O O    . HOH D 4 .   ? -27.153 -6.780  34.691 1.000 56.270  ? 1650 HOH AAA O    1 
HETATM 5335 O O    . HOH D 4 .   ? -9.667  1.148   15.080 1.000 55.080  ? 1651 HOH AAA O    1 
HETATM 5336 O O    . HOH D 4 .   ? -11.565 -13.286 22.443 1.000 85.920  ? 1652 HOH AAA O    1 
HETATM 5337 O O    . HOH D 4 .   ? -41.947 4.366   7.282  1.000 90.070  ? 1653 HOH AAA O    1 
HETATM 5338 O O    . HOH D 4 .   ? -46.663 -1.716  12.219 1.000 58.390  ? 1654 HOH AAA O    1 
HETATM 5339 O O    . HOH D 4 .   ? -33.214 -15.832 13.812 1.000 48.910  ? 1655 HOH AAA O    1 
HETATM 5340 O O    . HOH D 4 .   ? -14.167 2.225   33.310 1.000 62.070  ? 1656 HOH AAA O    1 
HETATM 5341 O O    . HOH D 4 .   ? -30.990 3.845   30.403 1.000 64.230  ? 1657 HOH AAA O    1 
HETATM 5342 O O    . HOH D 4 .   ? -29.759 -5.152  0.031  1.000 45.830  ? 1658 HOH AAA O    1 
HETATM 5343 O O    . HOH D 4 .   ? -12.507 8.290   17.190 1.000 41.770  ? 1659 HOH AAA O    1 
HETATM 5344 O O    . HOH D 4 .   ? -11.270 1.342   33.748 1.000 56.870  ? 1660 HOH AAA O    1 
HETATM 5345 O O    . HOH D 4 .   ? -10.963 5.888   4.518  1.000 47.200  ? 1661 HOH AAA O    1 
HETATM 5346 O O    . HOH D 4 .   ? -15.664 -10.871 11.086 1.000 55.980  ? 1662 HOH AAA O    1 
HETATM 5347 O O    . HOH D 4 .   ? -32.779 14.607  23.540 1.000 55.700  ? 1663 HOH AAA O    1 
HETATM 5348 O O    . HOH D 4 .   ? -44.405 8.625   20.766 1.000 51.500  ? 1664 HOH AAA O    1 
HETATM 5349 O O    . HOH D 4 .   ? -17.967 12.050  17.252 1.000 54.430  ? 1665 HOH AAA O    1 
HETATM 5350 O O    . HOH D 4 .   ? -8.788  1.497   32.994 1.000 72.540  ? 1666 HOH AAA O    1 
HETATM 5351 O O    . HOH D 4 .   ? -23.257 5.012   -2.314 1.000 48.460  ? 1667 HOH AAA O    1 
HETATM 5352 O O    . HOH D 4 .   ? -1.698  -0.560  10.121 1.000 74.470  ? 1668 HOH AAA O    1 
HETATM 5353 O O    . HOH D 4 .   ? -6.008  7.112   19.759 1.000 59.120  ? 1669 HOH AAA O    1 
HETATM 5354 O O    . HOH D 4 .   ? -27.691 17.588  12.766 1.000 54.890  ? 1670 HOH AAA O    1 
HETATM 5355 O O    . HOH D 4 .   ? -35.994 6.307   28.466 1.000 57.960  ? 1671 HOH AAA O    1 
HETATM 5356 O O    . HOH D 4 .   ? -46.337 0.391   5.517  1.000 52.810  ? 1672 HOH AAA O    1 
HETATM 5357 O O    . HOH D 4 .   ? -1.402  1.117   32.302 1.000 72.870  ? 1673 HOH AAA O    1 
HETATM 5358 O O    . HOH D 4 .   ? -13.172 -5.166  0.949  1.000 61.810  ? 1674 HOH AAA O    1 
HETATM 5359 O O    . HOH D 4 .   ? -26.240 -17.708 7.046  1.000 70.240  ? 1675 HOH AAA O    1 
HETATM 5360 O O    . HOH D 4 .   ? -33.071 -4.133  35.831 1.000 72.020  ? 1676 HOH AAA O    1 
HETATM 5361 O O    . HOH D 4 .   ? -10.390 10.600  15.676 1.000 60.940  ? 1677 HOH AAA O    1 
HETATM 5362 O O    . HOH D 4 .   ? -31.139 6.212   29.313 1.000 62.190  ? 1678 HOH AAA O    1 
HETATM 5363 O O    . HOH D 4 .   ? -13.399 18.602  36.892 1.000 74.490  ? 1679 HOH AAA O    1 
HETATM 5364 O O    . HOH D 4 .   ? -8.050  12.884  29.840 1.000 60.260  ? 1680 HOH AAA O    1 
HETATM 5365 O O    . HOH D 4 .   ? -6.582  1.331   34.297 1.000 75.260  ? 1681 HOH AAA O    1 
HETATM 5366 O O    . HOH D 4 .   ? -40.713 14.271  25.781 1.000 76.750  ? 1682 HOH AAA O    1 
HETATM 5367 O O    . HOH D 4 .   ? -15.131 18.432  20.806 1.000 79.490  ? 1683 HOH AAA O    1 
HETATM 5368 O O    . HOH D 4 .   ? 0.052   -1.114  11.686 1.000 84.720  ? 1684 HOH AAA O    1 
HETATM 5369 O O    . HOH D 4 .   ? -46.743 8.140   16.292 1.000 76.200  ? 1685 HOH AAA O    1 
HETATM 5370 O O    . HOH D 4 .   ? -38.816 13.532  27.483 1.000 66.610  ? 1686 HOH AAA O    1 
HETATM 5371 O O    . HOH D 4 .   ? -4.692  11.492  32.199 1.000 74.550  ? 1687 HOH AAA O    1 
HETATM 5372 O O    . HOH D 4 .   ? 2.156   -3.909  20.298 1.000 89.230  ? 1688 HOH AAA O    1 
HETATM 5373 O O    . HOH D 4 .   ? -20.481 18.716  34.744 1.000 75.690  ? 1689 HOH AAA O    1 
HETATM 5374 O O    . HOH D 4 .   ? 1.495   5.527   23.784 1.000 94.060  ? 1690 HOH AAA O    1 
HETATM 5375 O O    . HOH D 4 .   ? -50.384 -0.206  22.766 1.000 83.310  ? 1691 HOH AAA O    1 
HETATM 5376 O O    . HOH D 4 .   ? 0.475   9.230   18.447 1.000 81.360  ? 1692 HOH AAA O    1 
HETATM 5377 O O    . HOH D 4 .   ? 6.348   1.011   24.692 1.000 78.680  ? 1693 HOH AAA O    1 
HETATM 5378 O O    . HOH D 4 .   ? -10.391 -20.269 18.269 1.000 75.580  ? 1694 HOH AAA O    1 
HETATM 5379 O O    . HOH D 4 .   ? -36.272 4.700   37.682 1.000 72.650  ? 1695 HOH AAA O    1 
HETATM 5380 O O    . HOH D 4 .   ? -46.188 19.046  0.000  0.500 58.080  ? 1696 HOH AAA O    1 
HETATM 5381 O O    . HOH E 4 .   ? -17.873 -22.458 53.815 1.000 56.040  ? 201  HOH BBB O    1 
HETATM 5382 O O    . HOH E 4 .   ? -23.689 -9.678  64.659 1.000 36.600  ? 202  HOH BBB O    1 
HETATM 5383 O O    . HOH E 4 .   ? -20.281 -20.087 42.568 1.000 41.890  ? 203  HOH BBB O    1 
HETATM 5384 O O    . HOH E 4 .   ? -21.694 -5.990  53.556 1.000 47.520  ? 204  HOH BBB O    1 
HETATM 5385 O O    . HOH E 4 .   ? -8.463  -18.075 59.411 1.000 351.630 ? 205  HOH BBB O    1 
HETATM 5386 O O    . HOH E 4 .   ? -18.976 -1.080  42.103 1.000 58.040  ? 206  HOH BBB O    1 
HETATM 5387 O O    . HOH E 4 .   ? -26.305 -19.185 55.009 1.000 62.920  ? 207  HOH BBB O    1 
HETATM 5388 O O    . HOH E 4 .   ? -8.126  -4.211  58.807 1.000 49.000  ? 208  HOH BBB O    1 
HETATM 5389 O O    . HOH E 4 .   ? -10.655 -24.315 58.210 1.000 43.930  ? 209  HOH BBB O    1 
HETATM 5390 O O    . HOH E 4 .   ? -9.181  1.143   54.042 1.000 61.410  ? 210  HOH BBB O    1 
HETATM 5391 O O    . HOH E 4 .   ? -17.247 -15.508 72.132 1.000 61.340  ? 211  HOH BBB O    1 
HETATM 5392 O O    . HOH E 4 .   ? -17.392 -5.480  56.757 1.000 39.080  ? 212  HOH BBB O    1 
HETATM 5393 O O    . HOH E 4 .   ? -13.513 -4.771  64.812 1.000 54.630  ? 213  HOH BBB O    1 
HETATM 5394 O O    . HOH E 4 .   ? -23.831 -8.816  55.293 1.000 51.450  ? 214  HOH BBB O    1 
HETATM 5395 O O    . HOH E 4 .   ? -5.774  -12.793 74.520 1.000 67.020  ? 215  HOH BBB O    1 
HETATM 5396 O O    . HOH E 4 .   ? -2.577  -5.866  46.275 1.000 44.200  ? 216  HOH BBB O    1 
HETATM 5397 O O    . HOH E 4 .   ? -17.597 -8.676  69.669 1.000 46.000  ? 217  HOH BBB O    1 
HETATM 5398 O O    . HOH E 4 .   ? -13.847 -17.162 32.418 1.000 62.310  ? 218  HOH BBB O    1 
HETATM 5399 O O    . HOH E 4 .   ? -13.516 -14.617 33.351 1.000 68.240  ? 219  HOH BBB O    1 
HETATM 5400 O O    . HOH E 4 .   ? -28.966 -10.752 47.047 1.000 75.280  ? 220  HOH BBB O    1 
HETATM 5401 O O    . HOH E 4 .   ? -23.621 -10.641 36.476 1.000 46.800  ? 221  HOH BBB O    1 
HETATM 5402 O O    . HOH E 4 .   ? -12.465 -23.071 62.114 1.000 73.200  ? 222  HOH BBB O    1 
HETATM 5403 O O    . HOH E 4 .   ? -10.470 -22.918 46.228 1.000 82.950  ? 223  HOH BBB O    1 
HETATM 5404 O O    . HOH E 4 .   ? -8.438  -0.560  39.779 1.000 64.010  ? 224  HOH BBB O    1 
HETATM 5405 O O    . HOH E 4 .   ? -11.693 -29.809 57.096 1.000 64.540  ? 225  HOH BBB O    1 
HETATM 5406 O O    . HOH E 4 .   ? -17.960 0.379   46.698 1.000 53.330  ? 226  HOH BBB O    1 
HETATM 5407 O O    . HOH E 4 .   ? -23.458 -12.988 58.882 1.000 39.490  ? 227  HOH BBB O    1 
HETATM 5408 O O    . HOH E 4 .   ? -12.900 -24.697 50.187 1.000 57.790  ? 228  HOH BBB O    1 
HETATM 5409 O O    . HOH E 4 .   ? -17.581 -23.676 38.322 1.000 69.150  ? 229  HOH BBB O    1 
HETATM 5410 O O    . HOH E 4 .   ? -23.184 -23.945 57.755 1.000 58.600  ? 230  HOH BBB O    1 
HETATM 5411 O O    . HOH E 4 .   ? -19.579 -1.609  47.982 1.000 59.350  ? 231  HOH BBB O    1 
HETATM 5412 O O    . HOH E 4 .   ? -12.554 -24.322 59.681 1.000 52.450  ? 232  HOH BBB O    1 
HETATM 5413 O O    . HOH E 4 .   ? -12.996 -4.006  45.813 1.000 46.600  ? 233  HOH BBB O    1 
HETATM 5414 O O    . HOH E 4 .   ? -18.285 -13.655 45.661 1.000 34.140  ? 234  HOH BBB O    1 
HETATM 5415 O O    . HOH E 4 .   ? -13.799 5.759   49.464 1.000 51.990  ? 235  HOH BBB O    1 
HETATM 5416 O O    . HOH E 4 .   ? -25.901 -15.283 53.791 1.000 44.350  ? 236  HOH BBB O    1 
HETATM 5417 O O    . HOH E 4 .   ? -11.317 -24.095 68.844 1.000 72.510  ? 237  HOH BBB O    1 
HETATM 5418 O O    . HOH E 4 .   ? -2.604  -1.875  39.525 1.000 60.780  ? 238  HOH BBB O    1 
HETATM 5419 O O    . HOH E 4 .   ? -8.651  -17.687 75.025 1.000 74.830  ? 239  HOH BBB O    1 
HETATM 5420 O O    . HOH E 4 .   ? -3.037  -15.356 43.223 1.000 45.090  ? 240  HOH BBB O    1 
HETATM 5421 O O    . HOH E 4 .   ? -20.131 -3.100  50.520 1.000 43.180  ? 241  HOH BBB O    1 
HETATM 5422 O O    . HOH E 4 .   ? -14.978 -9.716  31.872 1.000 50.990  ? 242  HOH BBB O    1 
HETATM 5423 O O    . HOH E 4 .   ? 0.011   -13.492 59.742 1.000 56.000  ? 243  HOH BBB O    1 
HETATM 5424 O O    . HOH E 4 .   ? -0.190  -11.278 59.650 1.000 64.380  ? 244  HOH BBB O    1 
HETATM 5425 O O    . HOH E 4 .   ? -7.022  -23.346 45.105 1.000 51.940  ? 245  HOH BBB O    1 
HETATM 5426 O O    . HOH E 4 .   ? -25.205 -11.458 43.687 1.000 59.270  ? 246  HOH BBB O    1 
HETATM 5427 O O    . HOH E 4 .   ? -22.518 -16.705 39.525 1.000 67.580  ? 247  HOH BBB O    1 
HETATM 5428 O O    . HOH E 4 .   ? -1.578  -8.724  67.971 1.000 54.960  ? 248  HOH BBB O    1 
HETATM 5429 O O    . HOH E 4 .   ? 0.574   -15.212 57.781 1.000 65.920  ? 249  HOH BBB O    1 
HETATM 5430 O O    . HOH E 4 .   ? -10.302 -26.232 64.229 1.000 62.360  ? 250  HOH BBB O    1 
HETATM 5431 O O    . HOH E 4 .   ? -23.839 -23.517 48.485 1.000 60.830  ? 251  HOH BBB O    1 
HETATM 5432 O O    . HOH E 4 .   ? -15.777 -20.217 72.760 1.000 58.180  ? 252  HOH BBB O    1 
HETATM 5433 O O    . HOH E 4 .   ? -24.342 -1.822  47.744 1.000 64.180  ? 253  HOH BBB O    1 
HETATM 5434 O O    . HOH E 4 .   ? -25.715 -10.032 37.537 1.000 58.580  ? 254  HOH BBB O    1 
HETATM 5435 O O    . HOH E 4 .   ? -25.094 -12.496 34.066 1.000 57.270  ? 255  HOH BBB O    1 
HETATM 5436 O O    . HOH E 4 .   ? -23.907 -6.628  54.374 1.000 64.310  ? 256  HOH BBB O    1 
HETATM 5437 O O    . HOH E 4 .   ? -25.520 -17.303 46.282 1.000 71.240  ? 257  HOH BBB O    1 
HETATM 5438 O O    . HOH E 4 .   ? -8.172  -13.516 81.795 1.000 78.520  ? 258  HOH BBB O    1 
HETATM 5439 O O    . HOH E 4 .   ? 2.745   -11.568 33.882 1.000 68.050  ? 259  HOH BBB O    1 
HETATM 5440 O O    . HOH E 4 .   ? -28.308 -20.666 38.336 1.000 78.860  ? 260  HOH BBB O    1 
HETATM 5441 O O    . HOH E 4 .   ? -10.099 9.269   46.900 1.000 59.670  ? 261  HOH BBB O    1 
HETATM 5442 O O    . HOH E 4 .   ? -0.255  -21.275 73.347 1.000 104.480 ? 262  HOH BBB O    1 
HETATM 5443 O O    . HOH E 4 .   ? -5.038  -24.771 77.289 1.000 66.790  ? 263  HOH BBB O    1 
HETATM 5444 O O    . HOH E 4 .   ? -14.637 -24.012 77.056 1.000 68.410  ? 264  HOH BBB O    1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ILE 1   1262 1262 ILE ILE AAA . n 
A 1 2   SER 2   1263 1263 SER SER AAA . n 
A 1 3   GLU 3   1264 1264 GLU GLU AAA . n 
A 1 4   PRO 4   1265 1265 PRO PRO AAA . n 
A 1 5   PRO 5   1266 1266 PRO PRO AAA . n 
A 1 6   LEU 6   1267 1267 LEU LEU AAA . n 
A 1 7   HIS 7   1268 1268 HIS HIS AAA . n 
A 1 8   ASP 8   1269 1269 ASP ASP AAA . n 
A 1 9   PHE 9   1270 1270 PHE PHE AAA . n 
A 1 10  TYR 10  1271 1271 TYR TYR AAA . n 
A 1 11  CYS 11  1272 1272 CYS CYS AAA . n 
A 1 12  SER 12  1273 1273 SER SER AAA . n 
A 1 13  ARG 13  1274 1274 ARG ARG AAA . n 
A 1 14  LEU 14  1275 1275 LEU LEU AAA . n 
A 1 15  LEU 15  1276 1276 LEU LEU AAA . n 
A 1 16  ASP 16  1277 1277 ASP ASP AAA . n 
A 1 17  LEU 17  1278 1278 LEU LEU AAA . n 
A 1 18  VAL 18  1279 1279 VAL VAL AAA . n 
A 1 19  PHE 19  1280 1280 PHE PHE AAA . n 
A 1 20  LEU 20  1281 1281 LEU LEU AAA . n 
A 1 21  LEU 21  1282 1282 LEU LEU AAA . n 
A 1 22  ASP 22  1283 1283 ASP ASP AAA . n 
A 1 23  GLY 23  1284 1284 GLY GLY AAA . n 
A 1 24  SER 24  1285 1285 SER SER AAA . n 
A 1 25  SER 25  1286 1286 SER SER AAA . n 
A 1 26  ARG 26  1287 1287 ARG ARG AAA . n 
A 1 27  LEU 27  1288 1288 LEU LEU AAA . n 
A 1 28  SER 28  1289 1289 SER SER AAA . n 
A 1 29  GLU 29  1290 1290 GLU GLU AAA . n 
A 1 30  ALA 30  1291 1291 ALA ALA AAA . n 
A 1 31  GLU 31  1292 1292 GLU GLU AAA . n 
A 1 32  PHE 32  1293 1293 PHE PHE AAA . n 
A 1 33  GLU 33  1294 1294 GLU GLU AAA . n 
A 1 34  VAL 34  1295 1295 VAL VAL AAA . n 
A 1 35  LEU 35  1296 1296 LEU LEU AAA . n 
A 1 36  LYS 36  1297 1297 LYS LYS AAA . n 
A 1 37  ALA 37  1298 1298 ALA ALA AAA . n 
A 1 38  PHE 38  1299 1299 PHE PHE AAA . n 
A 1 39  VAL 39  1300 1300 VAL VAL AAA . n 
A 1 40  VAL 40  1301 1301 VAL VAL AAA . n 
A 1 41  ASP 41  1302 1302 ASP ASP AAA . n 
A 1 42  MET 42  1303 1303 MET MET AAA . n 
A 1 43  MET 43  1304 1304 MET MET AAA . n 
A 1 44  GLU 44  1305 1305 GLU GLU AAA . n 
A 1 45  ARG 45  1306 1306 ARG ARG AAA . n 
A 1 46  LEU 46  1307 1307 LEU LEU AAA . n 
A 1 47  ARG 47  1308 1308 ARG ARG AAA . n 
A 1 48  ILE 48  1309 1309 ILE ILE AAA . n 
A 1 49  SER 49  1310 1310 SER SER AAA . n 
A 1 50  GLN 50  1311 1311 GLN GLN AAA . n 
A 1 51  LYS 51  1312 1312 LYS LYS AAA . n 
A 1 52  TRP 52  1313 1313 TRP TRP AAA . n 
A 1 53  VAL 53  1314 1314 VAL VAL AAA . n 
A 1 54  ARG 54  1315 1315 ARG ARG AAA . n 
A 1 55  VAL 55  1316 1316 VAL VAL AAA . n 
A 1 56  ALA 56  1317 1317 ALA ALA AAA . n 
A 1 57  VAL 57  1318 1318 VAL VAL AAA . n 
A 1 58  VAL 58  1319 1319 VAL VAL AAA . n 
A 1 59  GLU 59  1320 1320 GLU GLU AAA . n 
A 1 60  TYR 60  1321 1321 TYR TYR AAA . n 
A 1 61  HIS 61  1322 1322 HIS HIS AAA . n 
A 1 62  ASP 62  1323 1323 ASP ASP AAA . n 
A 1 63  GLY 63  1324 1324 GLY GLY AAA . n 
A 1 64  SER 64  1325 1325 SER SER AAA . n 
A 1 65  HIS 65  1326 1326 HIS HIS AAA . n 
A 1 66  ALA 66  1327 1327 ALA ALA AAA . n 
A 1 67  TYR 67  1328 1328 TYR TYR AAA . n 
A 1 68  ILE 68  1329 1329 ILE ILE AAA . n 
A 1 69  GLY 69  1330 1330 GLY GLY AAA . n 
A 1 70  LEU 70  1331 1331 LEU LEU AAA . n 
A 1 71  LYS 71  1332 1332 LYS LYS AAA . n 
A 1 72  ASP 72  1333 1333 ASP ASP AAA . n 
A 1 73  ARG 73  1334 1334 ARG ARG AAA . n 
A 1 74  LYS 74  1335 1335 LYS LYS AAA . n 
A 1 75  ARG 75  1336 1336 ARG ARG AAA . n 
A 1 76  PRO 76  1337 1337 PRO PRO AAA . n 
A 1 77  SER 77  1338 1338 SER SER AAA . n 
A 1 78  GLU 78  1339 1339 GLU GLU AAA . n 
A 1 79  LEU 79  1340 1340 LEU LEU AAA . n 
A 1 80  ARG 80  1341 1341 ARG ARG AAA . n 
A 1 81  ARG 81  1342 1342 ARG ARG AAA . n 
A 1 82  ILE 82  1343 1343 ILE ILE AAA . n 
A 1 83  ALA 83  1344 1344 ALA ALA AAA . n 
A 1 84  SER 84  1345 1345 SER SER AAA . n 
A 1 85  GLN 85  1346 1346 GLN GLN AAA . n 
A 1 86  VAL 86  1347 1347 VAL VAL AAA . n 
A 1 87  LYS 87  1348 1348 LYS LYS AAA . n 
A 1 88  TYR 88  1349 1349 TYR TYR AAA . n 
A 1 89  ALA 89  1350 1350 ALA ALA AAA . n 
A 1 90  GLY 90  1351 1351 GLY GLY AAA . n 
A 1 91  SER 91  1352 1352 SER SER AAA . n 
A 1 92  GLN 92  1353 1353 GLN GLN AAA . n 
A 1 93  VAL 93  1354 1354 VAL VAL AAA . n 
A 1 94  ALA 94  1355 1355 ALA ALA AAA . n 
A 1 95  SER 95  1356 1356 SER SER AAA . n 
A 1 96  THR 96  1357 1357 THR THR AAA . n 
A 1 97  SER 97  1358 1358 SER SER AAA . n 
A 1 98  GLU 98  1359 1359 GLU GLU AAA . n 
A 1 99  VAL 99  1360 1360 VAL VAL AAA . n 
A 1 100 LEU 100 1361 1361 LEU LEU AAA . n 
A 1 101 LYS 101 1362 1362 LYS LYS AAA . n 
A 1 102 TYR 102 1363 1363 TYR TYR AAA . n 
A 1 103 THR 103 1364 1364 THR THR AAA . n 
A 1 104 LEU 104 1365 1365 LEU LEU AAA . n 
A 1 105 PHE 105 1366 1366 PHE PHE AAA . n 
A 1 106 GLN 106 1367 1367 GLN GLN AAA . n 
A 1 107 ILE 107 1368 1368 ILE ILE AAA . n 
A 1 108 PHE 108 1369 1369 PHE PHE AAA . n 
A 1 109 SER 109 1370 1370 SER SER AAA . n 
A 1 110 LYS 110 1371 1371 LYS LYS AAA . n 
A 1 111 ILE 111 1372 1372 ILE ILE AAA . n 
A 1 112 ASP 112 1373 1373 ASP ASP AAA . n 
A 1 113 ARG 113 1374 1374 ARG ARG AAA . n 
A 1 114 PRO 114 1375 1375 PRO PRO AAA . n 
A 1 115 GLU 115 1376 1376 GLU GLU AAA . n 
A 1 116 ALA 116 1377 1377 ALA ALA AAA . n 
A 1 117 SER 117 1378 1378 SER SER AAA . n 
A 1 118 ARG 118 1379 1379 ARG ARG AAA . n 
A 1 119 ILE 119 1380 1380 ILE ILE AAA . n 
A 1 120 ALA 120 1381 1381 ALA ALA AAA . n 
A 1 121 LEU 121 1382 1382 LEU LEU AAA . n 
A 1 122 LEU 122 1383 1383 LEU LEU AAA . n 
A 1 123 LEU 123 1384 1384 LEU LEU AAA . n 
A 1 124 MET 124 1385 1385 MET MET AAA . n 
A 1 125 ALA 125 1386 1386 ALA ALA AAA . n 
A 1 126 SER 126 1387 1387 SER SER AAA . n 
A 1 127 GLN 127 1388 1388 GLN GLN AAA . n 
A 1 128 GLU 128 1389 1389 GLU GLU AAA . n 
A 1 129 PRO 129 1390 1390 PRO PRO AAA . n 
A 1 130 GLN 130 1391 1391 GLN GLN AAA . n 
A 1 131 ARG 131 1392 1392 ARG ARG AAA . n 
A 1 132 MET 132 1393 1393 MET MET AAA . n 
A 1 133 SER 133 1394 1394 SER SER AAA . n 
A 1 134 ARG 134 1395 1395 ARG ARG AAA . n 
A 1 135 ASN 135 1396 1396 ASN ASN AAA . n 
A 1 136 PHE 136 1397 1397 PHE PHE AAA . n 
A 1 137 VAL 137 1398 1398 VAL VAL AAA . n 
A 1 138 ARG 138 1399 1399 ARG ARG AAA . n 
A 1 139 TYR 139 1400 1400 TYR TYR AAA . n 
A 1 140 VAL 140 1401 1401 VAL VAL AAA . n 
A 1 141 GLN 141 1402 1402 GLN GLN AAA . n 
A 1 142 GLY 142 1403 1403 GLY GLY AAA . n 
A 1 143 LEU 143 1404 1404 LEU LEU AAA . n 
A 1 144 LYS 144 1405 1405 LYS LYS AAA . n 
A 1 145 LYS 145 1406 1406 LYS LYS AAA . n 
A 1 146 LYS 146 1407 1407 LYS LYS AAA . n 
A 1 147 LYS 147 1408 1408 LYS LYS AAA . n 
A 1 148 VAL 148 1409 1409 VAL VAL AAA . n 
A 1 149 ILE 149 1410 1410 ILE ILE AAA . n 
A 1 150 VAL 150 1411 1411 VAL VAL AAA . n 
A 1 151 ILE 151 1412 1412 ILE ILE AAA . n 
A 1 152 PRO 152 1413 1413 PRO PRO AAA . n 
A 1 153 VAL 153 1414 1414 VAL VAL AAA . n 
A 1 154 GLY 154 1415 1415 GLY GLY AAA . n 
A 1 155 ILE 155 1416 1416 ILE ILE AAA . n 
A 1 156 GLY 156 1417 1417 GLY GLY AAA . n 
A 1 157 PRO 157 1418 1418 PRO PRO AAA . n 
A 1 158 HIS 158 1419 1419 HIS HIS AAA . n 
A 1 159 ALA 159 1420 1420 ALA ALA AAA . n 
A 1 160 ASN 160 1421 1421 ASN ASN AAA . n 
A 1 161 LEU 161 1422 1422 LEU LEU AAA . n 
A 1 162 LYS 162 1423 1423 LYS LYS AAA . n 
A 1 163 GLN 163 1424 1424 GLN GLN AAA . n 
A 1 164 ILE 164 1425 1425 ILE ILE AAA . n 
A 1 165 ARG 165 1426 1426 ARG ARG AAA . n 
A 1 166 LEU 166 1427 1427 LEU LEU AAA . n 
A 1 167 ILE 167 1428 1428 ILE ILE AAA . n 
A 1 168 GLU 168 1429 1429 GLU GLU AAA . n 
A 1 169 LYS 169 1430 1430 LYS LYS AAA . n 
A 1 170 GLN 170 1431 1431 GLN GLN AAA . n 
A 1 171 ALA 171 1432 1432 ALA ALA AAA . n 
A 1 172 PRO 172 1433 1433 PRO PRO AAA . n 
A 1 173 GLU 173 1434 1434 GLU GLU AAA . n 
A 1 174 ASN 174 1435 1435 ASN ASN AAA . n 
A 1 175 LYS 175 1436 1436 LYS LYS AAA . n 
A 1 176 ALA 176 1437 1437 ALA ALA AAA . n 
A 1 177 PHE 177 1438 1438 PHE PHE AAA . n 
A 1 178 VAL 178 1439 1439 VAL VAL AAA . n 
A 1 179 LEU 179 1440 1440 LEU LEU AAA . n 
A 1 180 SER 180 1441 1441 SER SER AAA . n 
A 1 181 SER 181 1442 1442 SER SER AAA . n 
A 1 182 VAL 182 1443 1443 VAL VAL AAA . n 
A 1 183 ASP 183 1444 1444 ASP ASP AAA . n 
A 1 184 GLU 184 1445 1445 GLU GLU AAA . n 
A 1 185 LEU 185 1446 1446 LEU LEU AAA . n 
A 1 186 GLU 186 1447 1447 GLU GLU AAA . n 
A 1 187 GLN 187 1448 1448 GLN GLN AAA . n 
A 1 188 GLN 188 1449 1449 GLN GLN AAA . n 
A 1 189 ARG 189 1450 1450 ARG ARG AAA . n 
A 1 190 ASP 190 1451 1451 ASP ASP AAA . n 
A 1 191 GLU 191 1452 1452 GLU GLU AAA . n 
A 1 192 ILE 192 1453 1453 ILE ILE AAA . n 
A 1 193 VAL 193 1454 1454 VAL VAL AAA . n 
A 1 194 SER 194 1455 1455 SER SER AAA . n 
A 1 195 TYR 195 1456 1456 TYR TYR AAA . n 
A 1 196 LEU 196 1457 1457 LEU LEU AAA . n 
A 1 197 CYS 197 1458 1458 CYS CYS AAA . n 
A 1 198 ASP 198 1459 1459 ASP ASP AAA . n 
A 1 199 LEU 199 1460 1460 LEU LEU AAA . n 
A 1 200 ALA 200 1461 1461 ALA ALA AAA . n 
A 1 201 PRO 201 1462 1462 PRO PRO AAA . n 
A 1 202 GLU 202 1463 1463 GLU GLU AAA . n 
A 1 203 ALA 203 1464 1464 ALA ALA AAA . n 
A 1 204 PRO 204 1465 1465 PRO PRO AAA . n 
A 1 205 PRO 205 1466 1466 PRO PRO AAA . n 
B 2 1   GLU 1   2    2    GLU GLU BBB . n 
B 2 2   VAL 2   3    3    VAL VAL BBB . n 
B 2 3   GLN 3   4    4    GLN GLN BBB . n 
B 2 4   LEU 4   5    5    LEU LEU BBB . n 
B 2 5   VAL 5   6    6    VAL VAL BBB . n 
B 2 6   GLU 6   7    7    GLU GLU BBB . n 
B 2 7   SER 7   8    8    SER SER BBB . n 
B 2 8   GLY 8   9    9    GLY GLY BBB . n 
B 2 9   GLY 9   10   10   GLY GLY BBB . n 
B 2 10  GLY 10  11   11   GLY GLY BBB . n 
B 2 11  LEU 11  12   12   LEU LEU BBB . n 
B 2 12  VAL 12  13   13   VAL VAL BBB . n 
B 2 13  GLN 13  14   14   GLN GLN BBB . n 
B 2 14  PRO 14  15   15   PRO PRO BBB . n 
B 2 15  GLY 15  16   16   GLY GLY BBB . n 
B 2 16  GLY 16  17   17   GLY GLY BBB . n 
B 2 17  SER 17  18   18   SER SER BBB . n 
B 2 18  LEU 18  19   19   LEU LEU BBB . n 
B 2 19  ARG 19  20   20   ARG ARG BBB . n 
B 2 20  LEU 20  21   21   LEU LEU BBB . n 
B 2 21  SER 21  22   22   SER SER BBB . n 
B 2 22  CYS 22  23   23   CYS CYS BBB . n 
B 2 23  ALA 23  24   24   ALA ALA BBB . n 
B 2 24  ALA 24  25   25   ALA ALA BBB . n 
B 2 25  SER 25  26   26   SER SER BBB . n 
B 2 26  GLY 26  27   27   GLY GLY BBB . n 
B 2 27  ARG 27  28   28   ARG ARG BBB . n 
B 2 28  THR 28  29   29   THR THR BBB . n 
B 2 29  PHE 29  30   30   PHE PHE BBB . n 
B 2 30  SER 30  31   31   SER SER BBB . n 
B 2 31  TYR 31  32   32   TYR TYR BBB . n 
B 2 32  ASN 32  33   33   ASN ASN BBB . n 
B 2 33  PRO 33  34   34   PRO PRO BBB . n 
B 2 34  MET 34  35   35   MET MET BBB . n 
B 2 35  GLY 35  36   36   GLY GLY BBB . n 
B 2 36  TRP 36  37   37   TRP TRP BBB . n 
B 2 37  PHE 37  38   38   PHE PHE BBB . n 
B 2 38  ARG 38  39   39   ARG ARG BBB . n 
B 2 39  GLN 39  40   40   GLN GLN BBB . n 
B 2 40  ALA 40  41   41   ALA ALA BBB . n 
B 2 41  PRO 41  42   42   PRO PRO BBB . n 
B 2 42  GLY 42  43   43   GLY GLY BBB . n 
B 2 43  LYS 43  44   44   LYS LYS BBB . n 
B 2 44  GLY 44  45   45   GLY GLY BBB . n 
B 2 45  ARG 45  46   46   ARG ARG BBB . n 
B 2 46  GLU 46  47   47   GLU GLU BBB . n 
B 2 47  LEU 47  48   48   LEU LEU BBB . n 
B 2 48  VAL 48  49   49   VAL VAL BBB . n 
B 2 49  ALA 49  50   50   ALA ALA BBB . n 
B 2 50  ALA 50  51   51   ALA ALA BBB . n 
B 2 51  ILE 51  52   52   ILE ILE BBB . n 
B 2 52  SER 52  53   53   SER SER BBB . n 
B 2 53  ARG 53  54   54   ARG ARG BBB . n 
B 2 54  THR 54  55   55   THR THR BBB . n 
B 2 55  GLY 55  56   56   GLY GLY BBB . n 
B 2 56  GLY 56  57   57   GLY GLY BBB . n 
B 2 57  SER 57  58   58   SER SER BBB . n 
B 2 58  THR 58  59   59   THR THR BBB . n 
B 2 59  TYR 59  60   60   TYR TYR BBB . n 
B 2 60  TYR 60  61   61   TYR TYR BBB . n 
B 2 61  PRO 61  62   62   PRO PRO BBB . n 
B 2 62  ASP 62  63   63   ASP ASP BBB . n 
B 2 63  SER 63  64   64   SER SER BBB . n 
B 2 64  VAL 64  65   65   VAL VAL BBB . n 
B 2 65  GLU 65  66   66   GLU GLU BBB . n 
B 2 66  GLY 66  67   67   GLY GLY BBB . n 
B 2 67  ARG 67  68   68   ARG ARG BBB . n 
B 2 68  PHE 68  69   69   PHE PHE BBB . n 
B 2 69  THR 69  70   70   THR THR BBB . n 
B 2 70  ILE 70  71   71   ILE ILE BBB . n 
B 2 71  SER 71  72   72   SER SER BBB . n 
B 2 72  ARG 72  73   73   ARG ARG BBB . n 
B 2 73  ASP 73  74   74   ASP ASP BBB . n 
B 2 74  ASN 74  75   75   ASN ASN BBB . n 
B 2 75  ALA 75  76   76   ALA ALA BBB . n 
B 2 76  LYS 76  77   77   LYS LYS BBB . n 
B 2 77  ARG 77  78   78   ARG ARG BBB . n 
B 2 78  MET 78  79   79   MET MET BBB . n 
B 2 79  VAL 79  80   80   VAL VAL BBB . n 
B 2 80  TYR 80  81   81   TYR TYR BBB . n 
B 2 81  LEU 81  82   82   LEU LEU BBB . n 
B 2 82  GLN 82  83   83   GLN GLN BBB . n 
B 2 83  MET 83  84   84   MET MET BBB . n 
B 2 84  ASN 84  85   85   ASN ASN BBB . n 
B 2 85  SER 85  86   86   SER SER BBB . n 
B 2 86  LEU 86  87   87   LEU LEU BBB . n 
B 2 87  ARG 87  88   88   ARG ARG BBB . n 
B 2 88  ALA 88  89   89   ALA ALA BBB . n 
B 2 89  GLU 89  90   90   GLU GLU BBB . n 
B 2 90  ASP 90  91   91   ASP ASP BBB . n 
B 2 91  THR 91  92   92   THR THR BBB . n 
B 2 92  ALA 92  93   93   ALA ALA BBB . n 
B 2 93  VAL 93  94   94   VAL VAL BBB . n 
B 2 94  TYR 94  95   95   TYR TYR BBB . n 
B 2 95  TYR 95  96   96   TYR TYR BBB . n 
B 2 96  CYS 96  97   97   CYS CYS BBB . n 
B 2 97  ALA 97  98   98   ALA ALA BBB . n 
B 2 98  ALA 98  99   99   ALA ALA BBB . n 
B 2 99  ALA 99  100  100  ALA ALA BBB . n 
B 2 100 GLY 100 101  101  GLY GLY BBB . n 
B 2 101 VAL 101 102  102  VAL VAL BBB . n 
B 2 102 ARG 102 103  103  ARG ARG BBB . n 
B 2 103 ALA 103 104  104  ALA ALA BBB . n 
B 2 104 GLU 104 105  105  GLU GLU BBB . n 
B 2 105 ASP 105 106  106  ASP ASP BBB . n 
B 2 106 GLY 106 107  107  GLY GLY BBB . n 
B 2 107 ARG 107 108  108  ARG ARG BBB . n 
B 2 108 VAL 108 109  109  VAL VAL BBB . n 
B 2 109 ARG 109 110  110  ARG ARG BBB . n 
B 2 110 THR 110 111  111  THR THR BBB . n 
B 2 111 LEU 111 112  112  LEU LEU BBB . n 
B 2 112 PRO 112 113  113  PRO PRO BBB . n 
B 2 113 SER 113 114  114  SER SER BBB . n 
B 2 114 GLU 114 115  115  GLU GLU BBB . n 
B 2 115 TYR 115 116  116  TYR TYR BBB . n 
B 2 116 THR 116 117  117  THR THR BBB . n 
B 2 117 PHE 117 118  118  PHE PHE BBB . n 
B 2 118 TRP 118 119  119  TRP TRP BBB . n 
B 2 119 GLY 119 120  120  GLY GLY BBB . n 
B 2 120 GLN 120 121  121  GLN GLN BBB . n 
B 2 121 GLY 121 122  122  GLY GLY BBB . n 
B 2 122 THR 122 123  123  THR THR BBB . n 
B 2 123 GLN 123 124  124  GLN GLN BBB . n 
B 2 124 VAL 124 125  125  VAL VAL BBB . n 
B 2 125 THR 125 126  126  THR THR BBB . n 
B 2 126 VAL 126 127  127  VAL VAL BBB . n 
B 2 127 SER 127 128  128  SER SER BBB . n 
B 2 128 SER 128 129  129  SER SER BBB . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 SO4 1  1501 1   SO4 SO4 AAA . 
D 4 HOH 1  1601 98  HOH HOH AAA . 
D 4 HOH 2  1602 170 HOH HOH AAA . 
D 4 HOH 3  1603 172 HOH HOH AAA . 
D 4 HOH 4  1604 36  HOH HOH AAA . 
D 4 HOH 5  1605 171 HOH HOH AAA . 
D 4 HOH 6  1606 108 HOH HOH AAA . 
D 4 HOH 7  1607 124 HOH HOH AAA . 
D 4 HOH 8  1608 65  HOH HOH AAA . 
D 4 HOH 9  1609 169 HOH HOH AAA . 
D 4 HOH 10 1610 173 HOH HOH AAA . 
D 4 HOH 11 1611 128 HOH HOH AAA . 
D 4 HOH 12 1612 54  HOH HOH AAA . 
D 4 HOH 13 1613 165 HOH HOH AAA . 
D 4 HOH 14 1614 82  HOH HOH AAA . 
D 4 HOH 15 1615 56  HOH HOH AAA . 
D 4 HOH 16 1616 174 HOH HOH AAA . 
D 4 HOH 17 1617 130 HOH HOH AAA . 
D 4 HOH 18 1618 143 HOH HOH AAA . 
D 4 HOH 19 1619 90  HOH HOH AAA . 
D 4 HOH 20 1620 17  HOH HOH AAA . 
D 4 HOH 21 1621 162 HOH HOH AAA . 
D 4 HOH 22 1622 119 HOH HOH AAA . 
D 4 HOH 23 1623 111 HOH HOH AAA . 
D 4 HOH 24 1624 91  HOH HOH AAA . 
D 4 HOH 25 1625 10  HOH HOH AAA . 
D 4 HOH 26 1626 202 HOH HOH AAA . 
D 4 HOH 27 1627 160 HOH HOH AAA . 
D 4 HOH 28 1628 23  HOH HOH AAA . 
D 4 HOH 29 1629 55  HOH HOH AAA . 
D 4 HOH 30 1630 5   HOH HOH AAA . 
D 4 HOH 31 1631 61  HOH HOH AAA . 
D 4 HOH 32 1632 20  HOH HOH AAA . 
D 4 HOH 33 1633 30  HOH HOH AAA . 
D 4 HOH 34 1634 72  HOH HOH AAA . 
D 4 HOH 35 1635 3   HOH HOH AAA . 
D 4 HOH 36 1636 38  HOH HOH AAA . 
D 4 HOH 37 1637 93  HOH HOH AAA . 
D 4 HOH 38 1638 1   HOH HOH AAA . 
D 4 HOH 39 1639 57  HOH HOH AAA . 
D 4 HOH 40 1640 16  HOH HOH AAA . 
D 4 HOH 41 1641 123 HOH HOH AAA . 
D 4 HOH 42 1642 88  HOH HOH AAA . 
D 4 HOH 43 1643 21  HOH HOH AAA . 
D 4 HOH 44 1644 50  HOH HOH AAA . 
D 4 HOH 45 1645 66  HOH HOH AAA . 
D 4 HOH 46 1646 40  HOH HOH AAA . 
D 4 HOH 47 1647 75  HOH HOH AAA . 
D 4 HOH 48 1648 167 HOH HOH AAA . 
D 4 HOH 49 1649 200 HOH HOH AAA . 
D 4 HOH 50 1650 205 HOH HOH AAA . 
D 4 HOH 51 1651 177 HOH HOH AAA . 
D 4 HOH 52 1652 196 HOH HOH AAA . 
D 4 HOH 53 1653 73  HOH HOH AAA . 
D 4 HOH 54 1654 14  HOH HOH AAA . 
D 4 HOH 55 1655 186 HOH HOH AAA . 
D 4 HOH 56 1656 94  HOH HOH AAA . 
D 4 HOH 57 1657 115 HOH HOH AAA . 
D 4 HOH 58 1658 178 HOH HOH AAA . 
D 4 HOH 59 1659 159 HOH HOH AAA . 
D 4 HOH 60 1660 187 HOH HOH AAA . 
D 4 HOH 61 1661 18  HOH HOH AAA . 
D 4 HOH 62 1662 213 HOH HOH AAA . 
D 4 HOH 63 1663 192 HOH HOH AAA . 
D 4 HOH 64 1664 149 HOH HOH AAA . 
D 4 HOH 65 1665 176 HOH HOH AAA . 
D 4 HOH 66 1666 51  HOH HOH AAA . 
D 4 HOH 67 1667 157 HOH HOH AAA . 
D 4 HOH 68 1668 141 HOH HOH AAA . 
D 4 HOH 69 1669 215 HOH HOH AAA . 
D 4 HOH 70 1670 199 HOH HOH AAA . 
D 4 HOH 71 1671 116 HOH HOH AAA . 
D 4 HOH 72 1672 180 HOH HOH AAA . 
D 4 HOH 73 1673 225 HOH HOH AAA . 
D 4 HOH 74 1674 118 HOH HOH AAA . 
D 4 HOH 75 1675 223 HOH HOH AAA . 
D 4 HOH 76 1676 220 HOH HOH AAA . 
D 4 HOH 77 1677 164 HOH HOH AAA . 
D 4 HOH 78 1678 151 HOH HOH AAA . 
D 4 HOH 79 1679 208 HOH HOH AAA . 
D 4 HOH 80 1680 193 HOH HOH AAA . 
D 4 HOH 81 1681 204 HOH HOH AAA . 
D 4 HOH 82 1682 206 HOH HOH AAA . 
D 4 HOH 83 1683 207 HOH HOH AAA . 
D 4 HOH 84 1684 153 HOH HOH AAA . 
D 4 HOH 85 1685 197 HOH HOH AAA . 
D 4 HOH 86 1686 179 HOH HOH AAA . 
D 4 HOH 87 1687 210 HOH HOH AAA . 
D 4 HOH 88 1688 191 HOH HOH AAA . 
D 4 HOH 89 1689 195 HOH HOH AAA . 
D 4 HOH 90 1690 224 HOH HOH AAA . 
D 4 HOH 91 1691 201 HOH HOH AAA . 
D 4 HOH 92 1692 219 HOH HOH AAA . 
D 4 HOH 93 1693 194 HOH HOH AAA . 
D 4 HOH 94 1694 216 HOH HOH AAA . 
D 4 HOH 95 1695 214 HOH HOH AAA . 
D 4 HOH 96 1696 212 HOH HOH AAA . 
E 4 HOH 1  201  81  HOH HOH BBB . 
E 4 HOH 2  202  158 HOH HOH BBB . 
E 4 HOH 3  203  168 HOH HOH BBB . 
E 4 HOH 4  204  39  HOH HOH BBB . 
E 4 HOH 5  205  144 HOH HOH BBB . 
E 4 HOH 6  206  29  HOH HOH BBB . 
E 4 HOH 7  207  92  HOH HOH BBB . 
E 4 HOH 8  208  4   HOH HOH BBB . 
E 4 HOH 9  209  8   HOH HOH BBB . 
E 4 HOH 10 210  181 HOH HOH BBB . 
E 4 HOH 11 211  85  HOH HOH BBB . 
E 4 HOH 12 212  28  HOH HOH BBB . 
E 4 HOH 13 213  60  HOH HOH BBB . 
E 4 HOH 14 214  19  HOH HOH BBB . 
E 4 HOH 15 215  95  HOH HOH BBB . 
E 4 HOH 16 216  45  HOH HOH BBB . 
E 4 HOH 17 217  109 HOH HOH BBB . 
E 4 HOH 18 218  68  HOH HOH BBB . 
E 4 HOH 19 219  87  HOH HOH BBB . 
E 4 HOH 20 220  27  HOH HOH BBB . 
E 4 HOH 21 221  166 HOH HOH BBB . 
E 4 HOH 22 222  89  HOH HOH BBB . 
E 4 HOH 23 223  63  HOH HOH BBB . 
E 4 HOH 24 224  31  HOH HOH BBB . 
E 4 HOH 25 225  35  HOH HOH BBB . 
E 4 HOH 26 226  161 HOH HOH BBB . 
E 4 HOH 27 227  2   HOH HOH BBB . 
E 4 HOH 28 228  24  HOH HOH BBB . 
E 4 HOH 29 229  11  HOH HOH BBB . 
E 4 HOH 30 230  198 HOH HOH BBB . 
E 4 HOH 31 231  48  HOH HOH BBB . 
E 4 HOH 32 232  12  HOH HOH BBB . 
E 4 HOH 33 233  112 HOH HOH BBB . 
E 4 HOH 34 234  154 HOH HOH BBB . 
E 4 HOH 35 235  101 HOH HOH BBB . 
E 4 HOH 36 236  78  HOH HOH BBB . 
E 4 HOH 37 237  34  HOH HOH BBB . 
E 4 HOH 38 238  9   HOH HOH BBB . 
E 4 HOH 39 239  32  HOH HOH BBB . 
E 4 HOH 40 240  25  HOH HOH BBB . 
E 4 HOH 41 241  13  HOH HOH BBB . 
E 4 HOH 42 242  49  HOH HOH BBB . 
E 4 HOH 43 243  185 HOH HOH BBB . 
E 4 HOH 44 244  175 HOH HOH BBB . 
E 4 HOH 45 245  62  HOH HOH BBB . 
E 4 HOH 46 246  22  HOH HOH BBB . 
E 4 HOH 47 247  76  HOH HOH BBB . 
E 4 HOH 48 248  190 HOH HOH BBB . 
E 4 HOH 49 249  184 HOH HOH BBB . 
E 4 HOH 50 250  131 HOH HOH BBB . 
E 4 HOH 51 251  211 HOH HOH BBB . 
E 4 HOH 52 252  182 HOH HOH BBB . 
E 4 HOH 53 253  203 HOH HOH BBB . 
E 4 HOH 54 254  163 HOH HOH BBB . 
E 4 HOH 55 255  79  HOH HOH BBB . 
E 4 HOH 56 256  64  HOH HOH BBB . 
E 4 HOH 57 257  221 HOH HOH BBB . 
E 4 HOH 58 258  218 HOH HOH BBB . 
E 4 HOH 59 259  222 HOH HOH BBB . 
E 4 HOH 60 260  188 HOH HOH BBB . 
E 4 HOH 61 261  183 HOH HOH BBB . 
E 4 HOH 62 262  209 HOH HOH BBB . 
E 4 HOH 63 263  189 HOH HOH BBB . 
E 4 HOH 64 264  217 HOH HOH BBB . 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1280  ? 
1 MORE         -16   ? 
1 'SSA (A^2)'  15090 ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    AAA 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     1696 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   D 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2021-03-03 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0258 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? .        4 
# 
_pdbx_entry_details.entry_id                 7A6O 
_pdbx_entry_details.nonpolymer_details       ? 
_pdbx_entry_details.sequence_details         ? 
_pdbx_entry_details.compound_details         ? 
_pdbx_entry_details.source_details           ? 
_pdbx_entry_details.has_ligand_of_interest   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HH22 AAA ARG 1395 ? ? O    AAA HOH 1602 ? ? 1.34 
2 1 OE1  AAA GLU 1339 ? ? HH21 AAA ARG 1342 ? ? 1.44 
3 1 O    AAA LEU 1457 ? ? O    AAA HOH 1601 ? ? 1.92 
4 1 NH2  AAA ARG 1395 ? ? O    AAA HOH 1602 ? ? 2.02 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE BBB ARG 73 ? ? CZ BBB ARG 73 ? ? NH1 BBB ARG 73 ? ? 124.34 120.30 4.04  0.50 N 
2 1 NE BBB ARG 73 ? ? CZ BBB ARG 73 ? ? NH2 BBB ARG 73 ? ? 116.92 120.30 -3.38 0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU AAA 1264 ? ? 82.43   115.29  
2 1 SER AAA 1273 ? ? -108.33 77.03   
3 1 TRP AAA 1313 ? ? -115.07 -108.11 
4 1 HIS AAA 1322 ? ? -114.77 -123.41 
5 1 ASP AAA 1333 ? ? -55.11  100.47  
6 1 ALA AAA 1432 ? ? -174.09 144.46  
7 1 ALA AAA 1464 ? ? -26.28  84.82   
8 1 PRO BBB 42   ? ? -37.87  125.64  
9 1 ALA BBB 93   ? ? 172.45  168.62  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_1   AAA 
_pdbx_validate_peptide_omega.auth_seq_id_1    1465 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   AAA 
_pdbx_validate_peptide_omega.auth_seq_id_2    1466 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            149.38 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1  1 O ? AAA HOH 1688 ? 6.05  . 
2  1 O ? AAA HOH 1689 ? 6.45  . 
3  1 O ? AAA HOH 1690 ? 7.13  . 
4  1 O ? AAA HOH 1691 ? 7.63  . 
5  1 O ? AAA HOH 1692 ? 8.62  . 
6  1 O ? AAA HOH 1693 ? 9.28  . 
7  1 O ? AAA HOH 1694 ? 9.33  . 
8  1 O ? AAA HOH 1695 ? 9.73  . 
9  1 O ? AAA HOH 1696 ? 12.14 . 
10 1 O ? BBB HOH 261  ? 5.89  . 
11 1 O ? BBB HOH 262  ? 5.92  . 
12 1 O ? BBB HOH 263  ? 7.34  . 
13 1 O ? BBB HOH 264  ? 8.42  . 
# 
_pdbx_audit_support.funding_organization   'British Heart Foundation' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           FS/18/70/33893 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'SULFATE ION' SO4 
4 water         HOH 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
