data_7EY4
# 
_entry.id   7EY4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.348 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7EY4         pdb_00007ey4 10.2210/pdb7ey4/pdb 
WWPDB D_1300022499 ?            ?                   
EMDB  EMD-31377    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Local CryoEM of the SARS-CoV-2 S6PV2 in complex with BD5537' 
_pdbx_database_related.db_id          EMD-31377 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7EY4 
_pdbx_database_status.recvd_initial_deposition_date   2021-05-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_audit_author.name               'Liu, P.L.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   CN 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Res.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1001-0602 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.' 
_citation.year                      2021 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41422-021-00555-0 
_citation.pdbx_database_id_PubMed   34433900 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Du, S.'       1  0000-0003-0936-0785 
primary 'Liu, P.'      2  ?                   
primary 'Zhang, Z.'    3  0000-0002-5690-9796 
primary 'Xiao, T.'     4  ?                   
primary 'Yasimayi, A.' 5  ?                   
primary 'Huang, W.'    6  0000-0002-4246-8889 
primary 'Wang, Y.'     7  0000-0001-9769-5141 
primary 'Cao, Y.'      8  0000-0001-5918-1078 
primary 'Xie, X.S.'    9  0000-0001-9281-5239 
primary 'Xiao, J.'     10 0000-0003-1822-1701 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7EY4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         7EY4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man 'BD-667 L' 23615.217  1 ? ? ? ? 
2 polymer  man 'BD-667 H' 25748.564  1 ? ? ? ? 
3 polymer  man 'Spike glycoprotein' 142066.094 1 ? ? ? ? 
4 polymer  man NTD 32657.969  1 ? ? ? ? 
5 branched man 
'beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 586.542    1 
? ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'S glycoprotein,E2,Peplomer protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EIVMTQSPATLSVSPGERATLSCRASQSVSRNLAWYQQRPGQAPRLLIYGASTRATGVAARFTGSGFGTEFTLTISGLQS
EDFAVYYCQEYNNWPPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;EIVMTQSPATLSVSPGERATLSCRASQSVSRNLAWYQQRPGQAPRLLIYGASTRATGVAARFTGSGFGTEFTLTISGLQS
EDFAVYYCQEYNNWPPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
2 'polypeptide(L)' no no 
;QVQLVESGGGLVKPGGSLRLSCAASGFRFSDYYMNWIRQAPGKGLEWISYIGSGGFATYYGDSVKGRFTVSRDDAENSLY
LQMNSLRAEDTAVYYCARGVTSYSDNSGNYRTDDAFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKHHHHHH
;
;QVQLVESGGGLVKPGGSLRLSCAASGFRFSDYYMNWIRQAPGKGLEWISYIGSGGFATYYGDSVKGRFTVSRDDAENSLY
LQMNSLRAEDTAVYYCARGVTSYSDNSGNYRTDDAFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKHHHHHH
;
H ? 
3 'polypeptide(L)' no no 
;MFVFLVLLPLVSSQCVNFTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFA
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRGLPQGFSALEPLVDLPIGINITRFQT
LHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPT
ESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIR
GDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGV
KGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQ
QFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVF
QTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPGSASSVASQSIIAYTMSLGVENSVAYSNNSIAIPTNFTISVT
TEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFS
QILPDPSKPSKRSPIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTIT
SGWTFGAGPALQIPFPMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTPSALGKLQDVVNQNAQALNTLV
KQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFC
GKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVS
GNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL
GKYEQGSGYIPEAPRDGQAYVRKDGEWVLLSTFLGRSLEVLFQGPGHHHHHHHHSAWSHPQFEKGGGSGGGGSGGSAWSH
PQFEK
;
;MFVFLVLLPLVSSQCVNFTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFA
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRGLPQGFSALEPLVDLPIGINITRFQT
LHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPT
ESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIR
GDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGV
KGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQ
QFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVF
QTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPGSASSVASQSIIAYTMSLGVENSVAYSNNSIAIPTNFTISVT
TEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFS
QILPDPSKPSKRSPIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTIT
SGWTFGAGPALQIPFPMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTPSALGKLQDVVNQNAQALNTLV
KQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFC
GKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVS
GNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL
GKYEQGSGYIPEAPRDGQAYVRKDGEWVLLSTFLGRSLEVLFQGPGHHHHHHHHSAWSHPQFEKGGGSGGGGSGGSAWSH
PQFEK
;
R ? 
4 'polypeptide(L)' no no 
;MFVFLVLLPLVSSQCVNFTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFA
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRGLPQGFSALEPLVDLPIGINITRFQT
LHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVD
;
;MFVFLVLLPLVSSQCVNFTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFA
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRGLPQGFSALEPLVDLPIGINITRFQT
LHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVD
;
N ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    GLU n 
1 2    ILE n 
1 3    VAL n 
1 4    MET n 
1 5    THR n 
1 6    GLN n 
1 7    SER n 
1 8    PRO n 
1 9    ALA n 
1 10   THR n 
1 11   LEU n 
1 12   SER n 
1 13   VAL n 
1 14   SER n 
1 15   PRO n 
1 16   GLY n 
1 17   GLU n 
1 18   ARG n 
1 19   ALA n 
1 20   THR n 
1 21   LEU n 
1 22   SER n 
1 23   CYS n 
1 24   ARG n 
1 25   ALA n 
1 26   SER n 
1 27   GLN n 
1 28   SER n 
1 29   VAL n 
1 30   SER n 
1 31   ARG n 
1 32   ASN n 
1 33   LEU n 
1 34   ALA n 
1 35   TRP n 
1 36   TYR n 
1 37   GLN n 
1 38   GLN n 
1 39   ARG n 
1 40   PRO n 
1 41   GLY n 
1 42   GLN n 
1 43   ALA n 
1 44   PRO n 
1 45   ARG n 
1 46   LEU n 
1 47   LEU n 
1 48   ILE n 
1 49   TYR n 
1 50   GLY n 
1 51   ALA n 
1 52   SER n 
1 53   THR n 
1 54   ARG n 
1 55   ALA n 
1 56   THR n 
1 57   GLY n 
1 58   VAL n 
1 59   ALA n 
1 60   ALA n 
1 61   ARG n 
1 62   PHE n 
1 63   THR n 
1 64   GLY n 
1 65   SER n 
1 66   GLY n 
1 67   PHE n 
1 68   GLY n 
1 69   THR n 
1 70   GLU n 
1 71   PHE n 
1 72   THR n 
1 73   LEU n 
1 74   THR n 
1 75   ILE n 
1 76   SER n 
1 77   GLY n 
1 78   LEU n 
1 79   GLN n 
1 80   SER n 
1 81   GLU n 
1 82   ASP n 
1 83   PHE n 
1 84   ALA n 
1 85   VAL n 
1 86   TYR n 
1 87   TYR n 
1 88   CYS n 
1 89   GLN n 
1 90   GLU n 
1 91   TYR n 
1 92   ASN n 
1 93   ASN n 
1 94   TRP n 
1 95   PRO n 
1 96   PRO n 
1 97   TRP n 
1 98   THR n 
1 99   PHE n 
1 100  GLY n 
1 101  GLN n 
1 102  GLY n 
1 103  THR n 
1 104  LYS n 
1 105  VAL n 
1 106  GLU n 
1 107  ILE n 
1 108  LYS n 
1 109  ARG n 
1 110  THR n 
1 111  VAL n 
1 112  ALA n 
1 113  ALA n 
1 114  PRO n 
1 115  SER n 
1 116  VAL n 
1 117  PHE n 
1 118  ILE n 
1 119  PHE n 
1 120  PRO n 
1 121  PRO n 
1 122  SER n 
1 123  ASP n 
1 124  GLU n 
1 125  GLN n 
1 126  LEU n 
1 127  LYS n 
1 128  SER n 
1 129  GLY n 
1 130  THR n 
1 131  ALA n 
1 132  SER n 
1 133  VAL n 
1 134  VAL n 
1 135  CYS n 
1 136  LEU n 
1 137  LEU n 
1 138  ASN n 
1 139  ASN n 
1 140  PHE n 
1 141  TYR n 
1 142  PRO n 
1 143  ARG n 
1 144  GLU n 
1 145  ALA n 
1 146  LYS n 
1 147  VAL n 
1 148  GLN n 
1 149  TRP n 
1 150  LYS n 
1 151  VAL n 
1 152  ASP n 
1 153  ASN n 
1 154  ALA n 
1 155  LEU n 
1 156  GLN n 
1 157  SER n 
1 158  GLY n 
1 159  ASN n 
1 160  SER n 
1 161  GLN n 
1 162  GLU n 
1 163  SER n 
1 164  VAL n 
1 165  THR n 
1 166  GLU n 
1 167  GLN n 
1 168  ASP n 
1 169  SER n 
1 170  LYS n 
1 171  ASP n 
1 172  SER n 
1 173  THR n 
1 174  TYR n 
1 175  SER n 
1 176  LEU n 
1 177  SER n 
1 178  SER n 
1 179  THR n 
1 180  LEU n 
1 181  THR n 
1 182  LEU n 
1 183  SER n 
1 184  LYS n 
1 185  ALA n 
1 186  ASP n 
1 187  TYR n 
1 188  GLU n 
1 189  LYS n 
1 190  HIS n 
1 191  LYS n 
1 192  VAL n 
1 193  TYR n 
1 194  ALA n 
1 195  CYS n 
1 196  GLU n 
1 197  VAL n 
1 198  THR n 
1 199  HIS n 
1 200  GLN n 
1 201  GLY n 
1 202  LEU n 
1 203  SER n 
1 204  SER n 
1 205  PRO n 
1 206  VAL n 
1 207  THR n 
1 208  LYS n 
1 209  SER n 
1 210  PHE n 
1 211  ASN n 
1 212  ARG n 
1 213  GLY n 
1 214  GLU n 
1 215  CYS n 
2 1    GLN n 
2 2    VAL n 
2 3    GLN n 
2 4    LEU n 
2 5    VAL n 
2 6    GLU n 
2 7    SER n 
2 8    GLY n 
2 9    GLY n 
2 10   GLY n 
2 11   LEU n 
2 12   VAL n 
2 13   LYS n 
2 14   PRO n 
2 15   GLY n 
2 16   GLY n 
2 17   SER n 
2 18   LEU n 
2 19   ARG n 
2 20   LEU n 
2 21   SER n 
2 22   CYS n 
2 23   ALA n 
2 24   ALA n 
2 25   SER n 
2 26   GLY n 
2 27   PHE n 
2 28   ARG n 
2 29   PHE n 
2 30   SER n 
2 31   ASP n 
2 32   TYR n 
2 33   TYR n 
2 34   MET n 
2 35   ASN n 
2 36   TRP n 
2 37   ILE n 
2 38   ARG n 
2 39   GLN n 
2 40   ALA n 
2 41   PRO n 
2 42   GLY n 
2 43   LYS n 
2 44   GLY n 
2 45   LEU n 
2 46   GLU n 
2 47   TRP n 
2 48   ILE n 
2 49   SER n 
2 50   TYR n 
2 51   ILE n 
2 52   GLY n 
2 53   SER n 
2 54   GLY n 
2 55   GLY n 
2 56   PHE n 
2 57   ALA n 
2 58   THR n 
2 59   TYR n 
2 60   TYR n 
2 61   GLY n 
2 62   ASP n 
2 63   SER n 
2 64   VAL n 
2 65   LYS n 
2 66   GLY n 
2 67   ARG n 
2 68   PHE n 
2 69   THR n 
2 70   VAL n 
2 71   SER n 
2 72   ARG n 
2 73   ASP n 
2 74   ASP n 
2 75   ALA n 
2 76   GLU n 
2 77   ASN n 
2 78   SER n 
2 79   LEU n 
2 80   TYR n 
2 81   LEU n 
2 82   GLN n 
2 83   MET n 
2 84   ASN n 
2 85   SER n 
2 86   LEU n 
2 87   ARG n 
2 88   ALA n 
2 89   GLU n 
2 90   ASP n 
2 91   THR n 
2 92   ALA n 
2 93   VAL n 
2 94   TYR n 
2 95   TYR n 
2 96   CYS n 
2 97   ALA n 
2 98   ARG n 
2 99   GLY n 
2 100  VAL n 
2 101  THR n 
2 102  SER n 
2 103  TYR n 
2 104  SER n 
2 105  ASP n 
2 106  ASN n 
2 107  SER n 
2 108  GLY n 
2 109  ASN n 
2 110  TYR n 
2 111  ARG n 
2 112  THR n 
2 113  ASP n 
2 114  ASP n 
2 115  ALA n 
2 116  PHE n 
2 117  ASP n 
2 118  ILE n 
2 119  TRP n 
2 120  GLY n 
2 121  GLN n 
2 122  GLY n 
2 123  THR n 
2 124  MET n 
2 125  VAL n 
2 126  THR n 
2 127  VAL n 
2 128  SER n 
2 129  SER n 
2 130  ALA n 
2 131  SER n 
2 132  THR n 
2 133  LYS n 
2 134  GLY n 
2 135  PRO n 
2 136  SER n 
2 137  VAL n 
2 138  PHE n 
2 139  PRO n 
2 140  LEU n 
2 141  ALA n 
2 142  PRO n 
2 143  SER n 
2 144  SER n 
2 145  LYS n 
2 146  SER n 
2 147  THR n 
2 148  SER n 
2 149  GLY n 
2 150  GLY n 
2 151  THR n 
2 152  ALA n 
2 153  ALA n 
2 154  LEU n 
2 155  GLY n 
2 156  CYS n 
2 157  LEU n 
2 158  VAL n 
2 159  LYS n 
2 160  ASP n 
2 161  TYR n 
2 162  PHE n 
2 163  PRO n 
2 164  GLU n 
2 165  PRO n 
2 166  VAL n 
2 167  THR n 
2 168  VAL n 
2 169  SER n 
2 170  TRP n 
2 171  ASN n 
2 172  SER n 
2 173  GLY n 
2 174  ALA n 
2 175  LEU n 
2 176  THR n 
2 177  SER n 
2 178  GLY n 
2 179  VAL n 
2 180  HIS n 
2 181  THR n 
2 182  PHE n 
2 183  PRO n 
2 184  ALA n 
2 185  VAL n 
2 186  LEU n 
2 187  GLN n 
2 188  SER n 
2 189  SER n 
2 190  GLY n 
2 191  LEU n 
2 192  TYR n 
2 193  SER n 
2 194  LEU n 
2 195  SER n 
2 196  SER n 
2 197  VAL n 
2 198  VAL n 
2 199  THR n 
2 200  VAL n 
2 201  PRO n 
2 202  SER n 
2 203  SER n 
2 204  SER n 
2 205  LEU n 
2 206  GLY n 
2 207  THR n 
2 208  GLN n 
2 209  THR n 
2 210  TYR n 
2 211  ILE n 
2 212  CYS n 
2 213  ASN n 
2 214  VAL n 
2 215  ASN n 
2 216  HIS n 
2 217  LYS n 
2 218  PRO n 
2 219  SER n 
2 220  ASN n 
2 221  THR n 
2 222  LYS n 
2 223  VAL n 
2 224  ASP n 
2 225  LYS n 
2 226  LYS n 
2 227  VAL n 
2 228  GLU n 
2 229  PRO n 
2 230  LYS n 
2 231  SER n 
2 232  CYS n 
2 233  ASP n 
2 234  LYS n 
2 235  HIS n 
2 236  HIS n 
2 237  HIS n 
2 238  HIS n 
2 239  HIS n 
2 240  HIS n 
3 1    MET n 
3 2    PHE n 
3 3    VAL n 
3 4    PHE n 
3 5    LEU n 
3 6    VAL n 
3 7    LEU n 
3 8    LEU n 
3 9    PRO n 
3 10   LEU n 
3 11   VAL n 
3 12   SER n 
3 13   SER n 
3 14   GLN n 
3 15   CYS n 
3 16   VAL n 
3 17   ASN n 
3 18   PHE n 
3 19   THR n 
3 20   THR n 
3 21   ARG n 
3 22   THR n 
3 23   GLN n 
3 24   LEU n 
3 25   PRO n 
3 26   PRO n 
3 27   ALA n 
3 28   TYR n 
3 29   THR n 
3 30   ASN n 
3 31   SER n 
3 32   PHE n 
3 33   THR n 
3 34   ARG n 
3 35   GLY n 
3 36   VAL n 
3 37   TYR n 
3 38   TYR n 
3 39   PRO n 
3 40   ASP n 
3 41   LYS n 
3 42   VAL n 
3 43   PHE n 
3 44   ARG n 
3 45   SER n 
3 46   SER n 
3 47   VAL n 
3 48   LEU n 
3 49   HIS n 
3 50   SER n 
3 51   THR n 
3 52   GLN n 
3 53   ASP n 
3 54   LEU n 
3 55   PHE n 
3 56   LEU n 
3 57   PRO n 
3 58   PHE n 
3 59   PHE n 
3 60   SER n 
3 61   ASN n 
3 62   VAL n 
3 63   THR n 
3 64   TRP n 
3 65   PHE n 
3 66   HIS n 
3 67   ALA n 
3 68   ILE n 
3 69   HIS n 
3 70   VAL n 
3 71   SER n 
3 72   GLY n 
3 73   THR n 
3 74   ASN n 
3 75   GLY n 
3 76   THR n 
3 77   LYS n 
3 78   ARG n 
3 79   PHE n 
3 80   ALA n 
3 81   ASN n 
3 82   PRO n 
3 83   VAL n 
3 84   LEU n 
3 85   PRO n 
3 86   PHE n 
3 87   ASN n 
3 88   ASP n 
3 89   GLY n 
3 90   VAL n 
3 91   TYR n 
3 92   PHE n 
3 93   ALA n 
3 94   SER n 
3 95   THR n 
3 96   GLU n 
3 97   LYS n 
3 98   SER n 
3 99   ASN n 
3 100  ILE n 
3 101  ILE n 
3 102  ARG n 
3 103  GLY n 
3 104  TRP n 
3 105  ILE n 
3 106  PHE n 
3 107  GLY n 
3 108  THR n 
3 109  THR n 
3 110  LEU n 
3 111  ASP n 
3 112  SER n 
3 113  LYS n 
3 114  THR n 
3 115  GLN n 
3 116  SER n 
3 117  LEU n 
3 118  LEU n 
3 119  ILE n 
3 120  VAL n 
3 121  ASN n 
3 122  ASN n 
3 123  ALA n 
3 124  THR n 
3 125  ASN n 
3 126  VAL n 
3 127  VAL n 
3 128  ILE n 
3 129  LYS n 
3 130  VAL n 
3 131  CYS n 
3 132  GLU n 
3 133  PHE n 
3 134  GLN n 
3 135  PHE n 
3 136  CYS n 
3 137  ASN n 
3 138  ASP n 
3 139  PRO n 
3 140  PHE n 
3 141  LEU n 
3 142  GLY n 
3 143  VAL n 
3 144  TYR n 
3 145  TYR n 
3 146  HIS n 
3 147  LYS n 
3 148  ASN n 
3 149  ASN n 
3 150  LYS n 
3 151  SER n 
3 152  TRP n 
3 153  MET n 
3 154  GLU n 
3 155  SER n 
3 156  GLU n 
3 157  PHE n 
3 158  ARG n 
3 159  VAL n 
3 160  TYR n 
3 161  SER n 
3 162  SER n 
3 163  ALA n 
3 164  ASN n 
3 165  ASN n 
3 166  CYS n 
3 167  THR n 
3 168  PHE n 
3 169  GLU n 
3 170  TYR n 
3 171  VAL n 
3 172  SER n 
3 173  GLN n 
3 174  PRO n 
3 175  PHE n 
3 176  LEU n 
3 177  MET n 
3 178  ASP n 
3 179  LEU n 
3 180  GLU n 
3 181  GLY n 
3 182  LYS n 
3 183  GLN n 
3 184  GLY n 
3 185  ASN n 
3 186  PHE n 
3 187  LYS n 
3 188  ASN n 
3 189  LEU n 
3 190  ARG n 
3 191  GLU n 
3 192  PHE n 
3 193  VAL n 
3 194  PHE n 
3 195  LYS n 
3 196  ASN n 
3 197  ILE n 
3 198  ASP n 
3 199  GLY n 
3 200  TYR n 
3 201  PHE n 
3 202  LYS n 
3 203  ILE n 
3 204  TYR n 
3 205  SER n 
3 206  LYS n 
3 207  HIS n 
3 208  THR n 
3 209  PRO n 
3 210  ILE n 
3 211  ASN n 
3 212  LEU n 
3 213  VAL n 
3 214  ARG n 
3 215  GLY n 
3 216  LEU n 
3 217  PRO n 
3 218  GLN n 
3 219  GLY n 
3 220  PHE n 
3 221  SER n 
3 222  ALA n 
3 223  LEU n 
3 224  GLU n 
3 225  PRO n 
3 226  LEU n 
3 227  VAL n 
3 228  ASP n 
3 229  LEU n 
3 230  PRO n 
3 231  ILE n 
3 232  GLY n 
3 233  ILE n 
3 234  ASN n 
3 235  ILE n 
3 236  THR n 
3 237  ARG n 
3 238  PHE n 
3 239  GLN n 
3 240  THR n 
3 241  LEU n 
3 242  HIS n 
3 243  ARG n 
3 244  SER n 
3 245  TYR n 
3 246  LEU n 
3 247  THR n 
3 248  PRO n 
3 249  GLY n 
3 250  ASP n 
3 251  SER n 
3 252  SER n 
3 253  SER n 
3 254  GLY n 
3 255  TRP n 
3 256  THR n 
3 257  ALA n 
3 258  GLY n 
3 259  ALA n 
3 260  ALA n 
3 261  ALA n 
3 262  TYR n 
3 263  TYR n 
3 264  VAL n 
3 265  GLY n 
3 266  TYR n 
3 267  LEU n 
3 268  GLN n 
3 269  PRO n 
3 270  ARG n 
3 271  THR n 
3 272  PHE n 
3 273  LEU n 
3 274  LEU n 
3 275  LYS n 
3 276  TYR n 
3 277  ASN n 
3 278  GLU n 
3 279  ASN n 
3 280  GLY n 
3 281  THR n 
3 282  ILE n 
3 283  THR n 
3 284  ASP n 
3 285  ALA n 
3 286  VAL n 
3 287  ASP n 
3 288  CYS n 
3 289  ALA n 
3 290  LEU n 
3 291  ASP n 
3 292  PRO n 
3 293  LEU n 
3 294  SER n 
3 295  GLU n 
3 296  THR n 
3 297  LYS n 
3 298  CYS n 
3 299  THR n 
3 300  LEU n 
3 301  LYS n 
3 302  SER n 
3 303  PHE n 
3 304  THR n 
3 305  VAL n 
3 306  GLU n 
3 307  LYS n 
3 308  GLY n 
3 309  ILE n 
3 310  TYR n 
3 311  GLN n 
3 312  THR n 
3 313  SER n 
3 314  ASN n 
3 315  PHE n 
3 316  ARG n 
3 317  VAL n 
3 318  GLN n 
3 319  PRO n 
3 320  THR n 
3 321  GLU n 
3 322  SER n 
3 323  ILE n 
3 324  VAL n 
3 325  ARG n 
3 326  PHE n 
3 327  PRO n 
3 328  ASN n 
3 329  ILE n 
3 330  THR n 
3 331  ASN n 
3 332  LEU n 
3 333  CYS n 
3 334  PRO n 
3 335  PHE n 
3 336  GLY n 
3 337  GLU n 
3 338  VAL n 
3 339  PHE n 
3 340  ASN n 
3 341  ALA n 
3 342  THR n 
3 343  ARG n 
3 344  PHE n 
3 345  ALA n 
3 346  SER n 
3 347  VAL n 
3 348  TYR n 
3 349  ALA n 
3 350  TRP n 
3 351  ASN n 
3 352  ARG n 
3 353  LYS n 
3 354  ARG n 
3 355  ILE n 
3 356  SER n 
3 357  ASN n 
3 358  CYS n 
3 359  VAL n 
3 360  ALA n 
3 361  ASP n 
3 362  TYR n 
3 363  SER n 
3 364  VAL n 
3 365  LEU n 
3 366  TYR n 
3 367  ASN n 
3 368  SER n 
3 369  ALA n 
3 370  SER n 
3 371  PHE n 
3 372  SER n 
3 373  THR n 
3 374  PHE n 
3 375  LYS n 
3 376  CYS n 
3 377  TYR n 
3 378  GLY n 
3 379  VAL n 
3 380  SER n 
3 381  PRO n 
3 382  THR n 
3 383  LYS n 
3 384  LEU n 
3 385  ASN n 
3 386  ASP n 
3 387  LEU n 
3 388  CYS n 
3 389  PHE n 
3 390  THR n 
3 391  ASN n 
3 392  VAL n 
3 393  TYR n 
3 394  ALA n 
3 395  ASP n 
3 396  SER n 
3 397  PHE n 
3 398  VAL n 
3 399  ILE n 
3 400  ARG n 
3 401  GLY n 
3 402  ASP n 
3 403  GLU n 
3 404  VAL n 
3 405  ARG n 
3 406  GLN n 
3 407  ILE n 
3 408  ALA n 
3 409  PRO n 
3 410  GLY n 
3 411  GLN n 
3 412  THR n 
3 413  GLY n 
3 414  ASN n 
3 415  ILE n 
3 416  ALA n 
3 417  ASP n 
3 418  TYR n 
3 419  ASN n 
3 420  TYR n 
3 421  LYS n 
3 422  LEU n 
3 423  PRO n 
3 424  ASP n 
3 425  ASP n 
3 426  PHE n 
3 427  THR n 
3 428  GLY n 
3 429  CYS n 
3 430  VAL n 
3 431  ILE n 
3 432  ALA n 
3 433  TRP n 
3 434  ASN n 
3 435  SER n 
3 436  ASN n 
3 437  ASN n 
3 438  LEU n 
3 439  ASP n 
3 440  SER n 
3 441  LYS n 
3 442  VAL n 
3 443  GLY n 
3 444  GLY n 
3 445  ASN n 
3 446  TYR n 
3 447  ASN n 
3 448  TYR n 
3 449  LEU n 
3 450  TYR n 
3 451  ARG n 
3 452  LEU n 
3 453  PHE n 
3 454  ARG n 
3 455  LYS n 
3 456  SER n 
3 457  ASN n 
3 458  LEU n 
3 459  LYS n 
3 460  PRO n 
3 461  PHE n 
3 462  GLU n 
3 463  ARG n 
3 464  ASP n 
3 465  ILE n 
3 466  SER n 
3 467  THR n 
3 468  GLU n 
3 469  ILE n 
3 470  TYR n 
3 471  GLN n 
3 472  ALA n 
3 473  GLY n 
3 474  SER n 
3 475  THR n 
3 476  PRO n 
3 477  CYS n 
3 478  ASN n 
3 479  GLY n 
3 480  VAL n 
3 481  LYS n 
3 482  GLY n 
3 483  PHE n 
3 484  ASN n 
3 485  CYS n 
3 486  TYR n 
3 487  PHE n 
3 488  PRO n 
3 489  LEU n 
3 490  GLN n 
3 491  SER n 
3 492  TYR n 
3 493  GLY n 
3 494  PHE n 
3 495  GLN n 
3 496  PRO n 
3 497  THR n 
3 498  TYR n 
3 499  GLY n 
3 500  VAL n 
3 501  GLY n 
3 502  TYR n 
3 503  GLN n 
3 504  PRO n 
3 505  TYR n 
3 506  ARG n 
3 507  VAL n 
3 508  VAL n 
3 509  VAL n 
3 510  LEU n 
3 511  SER n 
3 512  PHE n 
3 513  GLU n 
3 514  LEU n 
3 515  LEU n 
3 516  HIS n 
3 517  ALA n 
3 518  PRO n 
3 519  ALA n 
3 520  THR n 
3 521  VAL n 
3 522  CYS n 
3 523  GLY n 
3 524  PRO n 
3 525  LYS n 
3 526  LYS n 
3 527  SER n 
3 528  THR n 
3 529  ASN n 
3 530  LEU n 
3 531  VAL n 
3 532  LYS n 
3 533  ASN n 
3 534  LYS n 
3 535  CYS n 
3 536  VAL n 
3 537  ASN n 
3 538  PHE n 
3 539  ASN n 
3 540  PHE n 
3 541  ASN n 
3 542  GLY n 
3 543  LEU n 
3 544  THR n 
3 545  GLY n 
3 546  THR n 
3 547  GLY n 
3 548  VAL n 
3 549  LEU n 
3 550  THR n 
3 551  GLU n 
3 552  SER n 
3 553  ASN n 
3 554  LYS n 
3 555  LYS n 
3 556  PHE n 
3 557  LEU n 
3 558  PRO n 
3 559  PHE n 
3 560  GLN n 
3 561  GLN n 
3 562  PHE n 
3 563  GLY n 
3 564  ARG n 
3 565  ASP n 
3 566  ILE n 
3 567  ALA n 
3 568  ASP n 
3 569  THR n 
3 570  THR n 
3 571  ASP n 
3 572  ALA n 
3 573  VAL n 
3 574  ARG n 
3 575  ASP n 
3 576  PRO n 
3 577  GLN n 
3 578  THR n 
3 579  LEU n 
3 580  GLU n 
3 581  ILE n 
3 582  LEU n 
3 583  ASP n 
3 584  ILE n 
3 585  THR n 
3 586  PRO n 
3 587  CYS n 
3 588  SER n 
3 589  PHE n 
3 590  GLY n 
3 591  GLY n 
3 592  VAL n 
3 593  SER n 
3 594  VAL n 
3 595  ILE n 
3 596  THR n 
3 597  PRO n 
3 598  GLY n 
3 599  THR n 
3 600  ASN n 
3 601  THR n 
3 602  SER n 
3 603  ASN n 
3 604  GLN n 
3 605  VAL n 
3 606  ALA n 
3 607  VAL n 
3 608  LEU n 
3 609  TYR n 
3 610  GLN n 
3 611  GLY n 
3 612  VAL n 
3 613  ASN n 
3 614  CYS n 
3 615  THR n 
3 616  GLU n 
3 617  VAL n 
3 618  PRO n 
3 619  VAL n 
3 620  ALA n 
3 621  ILE n 
3 622  HIS n 
3 623  ALA n 
3 624  ASP n 
3 625  GLN n 
3 626  LEU n 
3 627  THR n 
3 628  PRO n 
3 629  THR n 
3 630  TRP n 
3 631  ARG n 
3 632  VAL n 
3 633  TYR n 
3 634  SER n 
3 635  THR n 
3 636  GLY n 
3 637  SER n 
3 638  ASN n 
3 639  VAL n 
3 640  PHE n 
3 641  GLN n 
3 642  THR n 
3 643  ARG n 
3 644  ALA n 
3 645  GLY n 
3 646  CYS n 
3 647  LEU n 
3 648  ILE n 
3 649  GLY n 
3 650  ALA n 
3 651  GLU n 
3 652  HIS n 
3 653  VAL n 
3 654  ASN n 
3 655  ASN n 
3 656  SER n 
3 657  TYR n 
3 658  GLU n 
3 659  CYS n 
3 660  ASP n 
3 661  ILE n 
3 662  PRO n 
3 663  ILE n 
3 664  GLY n 
3 665  ALA n 
3 666  GLY n 
3 667  ILE n 
3 668  CYS n 
3 669  ALA n 
3 670  SER n 
3 671  TYR n 
3 672  GLN n 
3 673  THR n 
3 674  GLN n 
3 675  THR n 
3 676  ASN n 
3 677  SER n 
3 678  PRO n 
3 679  GLY n 
3 680  SER n 
3 681  ALA n 
3 682  SER n 
3 683  SER n 
3 684  VAL n 
3 685  ALA n 
3 686  SER n 
3 687  GLN n 
3 688  SER n 
3 689  ILE n 
3 690  ILE n 
3 691  ALA n 
3 692  TYR n 
3 693  THR n 
3 694  MET n 
3 695  SER n 
3 696  LEU n 
3 697  GLY n 
3 698  VAL n 
3 699  GLU n 
3 700  ASN n 
3 701  SER n 
3 702  VAL n 
3 703  ALA n 
3 704  TYR n 
3 705  SER n 
3 706  ASN n 
3 707  ASN n 
3 708  SER n 
3 709  ILE n 
3 710  ALA n 
3 711  ILE n 
3 712  PRO n 
3 713  THR n 
3 714  ASN n 
3 715  PHE n 
3 716  THR n 
3 717  ILE n 
3 718  SER n 
3 719  VAL n 
3 720  THR n 
3 721  THR n 
3 722  GLU n 
3 723  ILE n 
3 724  LEU n 
3 725  PRO n 
3 726  VAL n 
3 727  SER n 
3 728  MET n 
3 729  THR n 
3 730  LYS n 
3 731  THR n 
3 732  SER n 
3 733  VAL n 
3 734  ASP n 
3 735  CYS n 
3 736  THR n 
3 737  MET n 
3 738  TYR n 
3 739  ILE n 
3 740  CYS n 
3 741  GLY n 
3 742  ASP n 
3 743  SER n 
3 744  THR n 
3 745  GLU n 
3 746  CYS n 
3 747  SER n 
3 748  ASN n 
3 749  LEU n 
3 750  LEU n 
3 751  LEU n 
3 752  GLN n 
3 753  TYR n 
3 754  GLY n 
3 755  SER n 
3 756  PHE n 
3 757  CYS n 
3 758  THR n 
3 759  GLN n 
3 760  LEU n 
3 761  ASN n 
3 762  ARG n 
3 763  ALA n 
3 764  LEU n 
3 765  THR n 
3 766  GLY n 
3 767  ILE n 
3 768  ALA n 
3 769  VAL n 
3 770  GLU n 
3 771  GLN n 
3 772  ASP n 
3 773  LYS n 
3 774  ASN n 
3 775  THR n 
3 776  GLN n 
3 777  GLU n 
3 778  VAL n 
3 779  PHE n 
3 780  ALA n 
3 781  GLN n 
3 782  VAL n 
3 783  LYS n 
3 784  GLN n 
3 785  ILE n 
3 786  TYR n 
3 787  LYS n 
3 788  THR n 
3 789  PRO n 
3 790  PRO n 
3 791  ILE n 
3 792  LYS n 
3 793  ASP n 
3 794  PHE n 
3 795  GLY n 
3 796  GLY n 
3 797  PHE n 
3 798  ASN n 
3 799  PHE n 
3 800  SER n 
3 801  GLN n 
3 802  ILE n 
3 803  LEU n 
3 804  PRO n 
3 805  ASP n 
3 806  PRO n 
3 807  SER n 
3 808  LYS n 
3 809  PRO n 
3 810  SER n 
3 811  LYS n 
3 812  ARG n 
3 813  SER n 
3 814  PRO n 
3 815  ILE n 
3 816  GLU n 
3 817  ASP n 
3 818  LEU n 
3 819  LEU n 
3 820  PHE n 
3 821  ASN n 
3 822  LYS n 
3 823  VAL n 
3 824  THR n 
3 825  LEU n 
3 826  ALA n 
3 827  ASP n 
3 828  ALA n 
3 829  GLY n 
3 830  PHE n 
3 831  ILE n 
3 832  LYS n 
3 833  GLN n 
3 834  TYR n 
3 835  GLY n 
3 836  ASP n 
3 837  CYS n 
3 838  LEU n 
3 839  GLY n 
3 840  ASP n 
3 841  ILE n 
3 842  ALA n 
3 843  ALA n 
3 844  ARG n 
3 845  ASP n 
3 846  LEU n 
3 847  ILE n 
3 848  CYS n 
3 849  ALA n 
3 850  GLN n 
3 851  LYS n 
3 852  PHE n 
3 853  ASN n 
3 854  GLY n 
3 855  LEU n 
3 856  THR n 
3 857  VAL n 
3 858  LEU n 
3 859  PRO n 
3 860  PRO n 
3 861  LEU n 
3 862  LEU n 
3 863  THR n 
3 864  ASP n 
3 865  GLU n 
3 866  MET n 
3 867  ILE n 
3 868  ALA n 
3 869  GLN n 
3 870  TYR n 
3 871  THR n 
3 872  SER n 
3 873  ALA n 
3 874  LEU n 
3 875  LEU n 
3 876  ALA n 
3 877  GLY n 
3 878  THR n 
3 879  ILE n 
3 880  THR n 
3 881  SER n 
3 882  GLY n 
3 883  TRP n 
3 884  THR n 
3 885  PHE n 
3 886  GLY n 
3 887  ALA n 
3 888  GLY n 
3 889  PRO n 
3 890  ALA n 
3 891  LEU n 
3 892  GLN n 
3 893  ILE n 
3 894  PRO n 
3 895  PHE n 
3 896  PRO n 
3 897  MET n 
3 898  GLN n 
3 899  MET n 
3 900  ALA n 
3 901  TYR n 
3 902  ARG n 
3 903  PHE n 
3 904  ASN n 
3 905  GLY n 
3 906  ILE n 
3 907  GLY n 
3 908  VAL n 
3 909  THR n 
3 910  GLN n 
3 911  ASN n 
3 912  VAL n 
3 913  LEU n 
3 914  TYR n 
3 915  GLU n 
3 916  ASN n 
3 917  GLN n 
3 918  LYS n 
3 919  LEU n 
3 920  ILE n 
3 921  ALA n 
3 922  ASN n 
3 923  GLN n 
3 924  PHE n 
3 925  ASN n 
3 926  SER n 
3 927  ALA n 
3 928  ILE n 
3 929  GLY n 
3 930  LYS n 
3 931  ILE n 
3 932  GLN n 
3 933  ASP n 
3 934  SER n 
3 935  LEU n 
3 936  SER n 
3 937  SER n 
3 938  THR n 
3 939  PRO n 
3 940  SER n 
3 941  ALA n 
3 942  LEU n 
3 943  GLY n 
3 944  LYS n 
3 945  LEU n 
3 946  GLN n 
3 947  ASP n 
3 948  VAL n 
3 949  VAL n 
3 950  ASN n 
3 951  GLN n 
3 952  ASN n 
3 953  ALA n 
3 954  GLN n 
3 955  ALA n 
3 956  LEU n 
3 957  ASN n 
3 958  THR n 
3 959  LEU n 
3 960  VAL n 
3 961  LYS n 
3 962  GLN n 
3 963  LEU n 
3 964  SER n 
3 965  SER n 
3 966  ASN n 
3 967  PHE n 
3 968  GLY n 
3 969  ALA n 
3 970  ILE n 
3 971  SER n 
3 972  SER n 
3 973  VAL n 
3 974  LEU n 
3 975  ASN n 
3 976  ASP n 
3 977  ILE n 
3 978  LEU n 
3 979  SER n 
3 980  ARG n 
3 981  LEU n 
3 982  ASP n 
3 983  PRO n 
3 984  PRO n 
3 985  GLU n 
3 986  ALA n 
3 987  GLU n 
3 988  VAL n 
3 989  GLN n 
3 990  ILE n 
3 991  ASP n 
3 992  ARG n 
3 993  LEU n 
3 994  ILE n 
3 995  THR n 
3 996  GLY n 
3 997  ARG n 
3 998  LEU n 
3 999  GLN n 
3 1000 SER n 
3 1001 LEU n 
3 1002 GLN n 
3 1003 THR n 
3 1004 TYR n 
3 1005 VAL n 
3 1006 THR n 
3 1007 GLN n 
3 1008 GLN n 
3 1009 LEU n 
3 1010 ILE n 
3 1011 ARG n 
3 1012 ALA n 
3 1013 ALA n 
3 1014 GLU n 
3 1015 ILE n 
3 1016 ARG n 
3 1017 ALA n 
3 1018 SER n 
3 1019 ALA n 
3 1020 ASN n 
3 1021 LEU n 
3 1022 ALA n 
3 1023 ALA n 
3 1024 THR n 
3 1025 LYS n 
3 1026 MET n 
3 1027 SER n 
3 1028 GLU n 
3 1029 CYS n 
3 1030 VAL n 
3 1031 LEU n 
3 1032 GLY n 
3 1033 GLN n 
3 1034 SER n 
3 1035 LYS n 
3 1036 ARG n 
3 1037 VAL n 
3 1038 ASP n 
3 1039 PHE n 
3 1040 CYS n 
3 1041 GLY n 
3 1042 LYS n 
3 1043 GLY n 
3 1044 TYR n 
3 1045 HIS n 
3 1046 LEU n 
3 1047 MET n 
3 1048 SER n 
3 1049 PHE n 
3 1050 PRO n 
3 1051 GLN n 
3 1052 SER n 
3 1053 ALA n 
3 1054 PRO n 
3 1055 HIS n 
3 1056 GLY n 
3 1057 VAL n 
3 1058 VAL n 
3 1059 PHE n 
3 1060 LEU n 
3 1061 HIS n 
3 1062 VAL n 
3 1063 THR n 
3 1064 TYR n 
3 1065 VAL n 
3 1066 PRO n 
3 1067 ALA n 
3 1068 GLN n 
3 1069 GLU n 
3 1070 LYS n 
3 1071 ASN n 
3 1072 PHE n 
3 1073 THR n 
3 1074 THR n 
3 1075 ALA n 
3 1076 PRO n 
3 1077 ALA n 
3 1078 ILE n 
3 1079 CYS n 
3 1080 HIS n 
3 1081 ASP n 
3 1082 GLY n 
3 1083 LYS n 
3 1084 ALA n 
3 1085 HIS n 
3 1086 PHE n 
3 1087 PRO n 
3 1088 ARG n 
3 1089 GLU n 
3 1090 GLY n 
3 1091 VAL n 
3 1092 PHE n 
3 1093 VAL n 
3 1094 SER n 
3 1095 ASN n 
3 1096 GLY n 
3 1097 THR n 
3 1098 HIS n 
3 1099 TRP n 
3 1100 PHE n 
3 1101 VAL n 
3 1102 THR n 
3 1103 GLN n 
3 1104 ARG n 
3 1105 ASN n 
3 1106 PHE n 
3 1107 TYR n 
3 1108 GLU n 
3 1109 PRO n 
3 1110 GLN n 
3 1111 ILE n 
3 1112 ILE n 
3 1113 THR n 
3 1114 THR n 
3 1115 ASP n 
3 1116 ASN n 
3 1117 THR n 
3 1118 PHE n 
3 1119 VAL n 
3 1120 SER n 
3 1121 GLY n 
3 1122 ASN n 
3 1123 CYS n 
3 1124 ASP n 
3 1125 VAL n 
3 1126 VAL n 
3 1127 ILE n 
3 1128 GLY n 
3 1129 ILE n 
3 1130 VAL n 
3 1131 ASN n 
3 1132 ASN n 
3 1133 THR n 
3 1134 VAL n 
3 1135 TYR n 
3 1136 ASP n 
3 1137 PRO n 
3 1138 LEU n 
3 1139 GLN n 
3 1140 PRO n 
3 1141 GLU n 
3 1142 LEU n 
3 1143 ASP n 
3 1144 SER n 
3 1145 PHE n 
3 1146 LYS n 
3 1147 GLU n 
3 1148 GLU n 
3 1149 LEU n 
3 1150 ASP n 
3 1151 LYS n 
3 1152 TYR n 
3 1153 PHE n 
3 1154 LYS n 
3 1155 ASN n 
3 1156 HIS n 
3 1157 THR n 
3 1158 SER n 
3 1159 PRO n 
3 1160 ASP n 
3 1161 VAL n 
3 1162 ASP n 
3 1163 LEU n 
3 1164 GLY n 
3 1165 ASP n 
3 1166 ILE n 
3 1167 SER n 
3 1168 GLY n 
3 1169 ILE n 
3 1170 ASN n 
3 1171 ALA n 
3 1172 SER n 
3 1173 VAL n 
3 1174 VAL n 
3 1175 ASN n 
3 1176 ILE n 
3 1177 GLN n 
3 1178 LYS n 
3 1179 GLU n 
3 1180 ILE n 
3 1181 ASP n 
3 1182 ARG n 
3 1183 LEU n 
3 1184 ASN n 
3 1185 GLU n 
3 1186 VAL n 
3 1187 ALA n 
3 1188 LYS n 
3 1189 ASN n 
3 1190 LEU n 
3 1191 ASN n 
3 1192 GLU n 
3 1193 SER n 
3 1194 LEU n 
3 1195 ILE n 
3 1196 ASP n 
3 1197 LEU n 
3 1198 GLN n 
3 1199 GLU n 
3 1200 LEU n 
3 1201 GLY n 
3 1202 LYS n 
3 1203 TYR n 
3 1204 GLU n 
3 1205 GLN n 
3 1206 GLY n 
3 1207 SER n 
3 1208 GLY n 
3 1209 TYR n 
3 1210 ILE n 
3 1211 PRO n 
3 1212 GLU n 
3 1213 ALA n 
3 1214 PRO n 
3 1215 ARG n 
3 1216 ASP n 
3 1217 GLY n 
3 1218 GLN n 
3 1219 ALA n 
3 1220 TYR n 
3 1221 VAL n 
3 1222 ARG n 
3 1223 LYS n 
3 1224 ASP n 
3 1225 GLY n 
3 1226 GLU n 
3 1227 TRP n 
3 1228 VAL n 
3 1229 LEU n 
3 1230 LEU n 
3 1231 SER n 
3 1232 THR n 
3 1233 PHE n 
3 1234 LEU n 
3 1235 GLY n 
3 1236 ARG n 
3 1237 SER n 
3 1238 LEU n 
3 1239 GLU n 
3 1240 VAL n 
3 1241 LEU n 
3 1242 PHE n 
3 1243 GLN n 
3 1244 GLY n 
3 1245 PRO n 
3 1246 GLY n 
3 1247 HIS n 
3 1248 HIS n 
3 1249 HIS n 
3 1250 HIS n 
3 1251 HIS n 
3 1252 HIS n 
3 1253 HIS n 
3 1254 HIS n 
3 1255 SER n 
3 1256 ALA n 
3 1257 TRP n 
3 1258 SER n 
3 1259 HIS n 
3 1260 PRO n 
3 1261 GLN n 
3 1262 PHE n 
3 1263 GLU n 
3 1264 LYS n 
3 1265 GLY n 
3 1266 GLY n 
3 1267 GLY n 
3 1268 SER n 
3 1269 GLY n 
3 1270 GLY n 
3 1271 GLY n 
3 1272 GLY n 
3 1273 SER n 
3 1274 GLY n 
3 1275 GLY n 
3 1276 SER n 
3 1277 ALA n 
3 1278 TRP n 
3 1279 SER n 
3 1280 HIS n 
3 1281 PRO n 
3 1282 GLN n 
3 1283 PHE n 
3 1284 GLU n 
3 1285 LYS n 
4 1    MET n 
4 2    PHE n 
4 3    VAL n 
4 4    PHE n 
4 5    LEU n 
4 6    VAL n 
4 7    LEU n 
4 8    LEU n 
4 9    PRO n 
4 10   LEU n 
4 11   VAL n 
4 12   SER n 
4 13   SER n 
4 14   GLN n 
4 15   CYS n 
4 16   VAL n 
4 17   ASN n 
4 18   PHE n 
4 19   THR n 
4 20   THR n 
4 21   ARG n 
4 22   THR n 
4 23   GLN n 
4 24   LEU n 
4 25   PRO n 
4 26   PRO n 
4 27   ALA n 
4 28   TYR n 
4 29   THR n 
4 30   ASN n 
4 31   SER n 
4 32   PHE n 
4 33   THR n 
4 34   ARG n 
4 35   GLY n 
4 36   VAL n 
4 37   TYR n 
4 38   TYR n 
4 39   PRO n 
4 40   ASP n 
4 41   LYS n 
4 42   VAL n 
4 43   PHE n 
4 44   ARG n 
4 45   SER n 
4 46   SER n 
4 47   VAL n 
4 48   LEU n 
4 49   HIS n 
4 50   SER n 
4 51   THR n 
4 52   GLN n 
4 53   ASP n 
4 54   LEU n 
4 55   PHE n 
4 56   LEU n 
4 57   PRO n 
4 58   PHE n 
4 59   PHE n 
4 60   SER n 
4 61   ASN n 
4 62   VAL n 
4 63   THR n 
4 64   TRP n 
4 65   PHE n 
4 66   HIS n 
4 67   ALA n 
4 68   ILE n 
4 69   HIS n 
4 70   VAL n 
4 71   SER n 
4 72   GLY n 
4 73   THR n 
4 74   ASN n 
4 75   GLY n 
4 76   THR n 
4 77   LYS n 
4 78   ARG n 
4 79   PHE n 
4 80   ALA n 
4 81   ASN n 
4 82   PRO n 
4 83   VAL n 
4 84   LEU n 
4 85   PRO n 
4 86   PHE n 
4 87   ASN n 
4 88   ASP n 
4 89   GLY n 
4 90   VAL n 
4 91   TYR n 
4 92   PHE n 
4 93   ALA n 
4 94   SER n 
4 95   THR n 
4 96   GLU n 
4 97   LYS n 
4 98   SER n 
4 99   ASN n 
4 100  ILE n 
4 101  ILE n 
4 102  ARG n 
4 103  GLY n 
4 104  TRP n 
4 105  ILE n 
4 106  PHE n 
4 107  GLY n 
4 108  THR n 
4 109  THR n 
4 110  LEU n 
4 111  ASP n 
4 112  SER n 
4 113  LYS n 
4 114  THR n 
4 115  GLN n 
4 116  SER n 
4 117  LEU n 
4 118  LEU n 
4 119  ILE n 
4 120  VAL n 
4 121  ASN n 
4 122  ASN n 
4 123  ALA n 
4 124  THR n 
4 125  ASN n 
4 126  VAL n 
4 127  VAL n 
4 128  ILE n 
4 129  LYS n 
4 130  VAL n 
4 131  CYS n 
4 132  GLU n 
4 133  PHE n 
4 134  GLN n 
4 135  PHE n 
4 136  CYS n 
4 137  ASN n 
4 138  ASP n 
4 139  PRO n 
4 140  PHE n 
4 141  LEU n 
4 142  GLY n 
4 143  VAL n 
4 144  TYR n 
4 145  TYR n 
4 146  HIS n 
4 147  LYS n 
4 148  ASN n 
4 149  ASN n 
4 150  LYS n 
4 151  SER n 
4 152  TRP n 
4 153  MET n 
4 154  GLU n 
4 155  SER n 
4 156  GLU n 
4 157  PHE n 
4 158  ARG n 
4 159  VAL n 
4 160  TYR n 
4 161  SER n 
4 162  SER n 
4 163  ALA n 
4 164  ASN n 
4 165  ASN n 
4 166  CYS n 
4 167  THR n 
4 168  PHE n 
4 169  GLU n 
4 170  TYR n 
4 171  VAL n 
4 172  SER n 
4 173  GLN n 
4 174  PRO n 
4 175  PHE n 
4 176  LEU n 
4 177  MET n 
4 178  ASP n 
4 179  LEU n 
4 180  GLU n 
4 181  GLY n 
4 182  LYS n 
4 183  GLN n 
4 184  GLY n 
4 185  ASN n 
4 186  PHE n 
4 187  LYS n 
4 188  ASN n 
4 189  LEU n 
4 190  ARG n 
4 191  GLU n 
4 192  PHE n 
4 193  VAL n 
4 194  PHE n 
4 195  LYS n 
4 196  ASN n 
4 197  ILE n 
4 198  ASP n 
4 199  GLY n 
4 200  TYR n 
4 201  PHE n 
4 202  LYS n 
4 203  ILE n 
4 204  TYR n 
4 205  SER n 
4 206  LYS n 
4 207  HIS n 
4 208  THR n 
4 209  PRO n 
4 210  ILE n 
4 211  ASN n 
4 212  LEU n 
4 213  VAL n 
4 214  ARG n 
4 215  GLY n 
4 216  LEU n 
4 217  PRO n 
4 218  GLN n 
4 219  GLY n 
4 220  PHE n 
4 221  SER n 
4 222  ALA n 
4 223  LEU n 
4 224  GLU n 
4 225  PRO n 
4 226  LEU n 
4 227  VAL n 
4 228  ASP n 
4 229  LEU n 
4 230  PRO n 
4 231  ILE n 
4 232  GLY n 
4 233  ILE n 
4 234  ASN n 
4 235  ILE n 
4 236  THR n 
4 237  ARG n 
4 238  PHE n 
4 239  GLN n 
4 240  THR n 
4 241  LEU n 
4 242  HIS n 
4 243  ARG n 
4 244  SER n 
4 245  TYR n 
4 246  LEU n 
4 247  THR n 
4 248  PRO n 
4 249  GLY n 
4 250  ASP n 
4 251  SER n 
4 252  SER n 
4 253  SER n 
4 254  GLY n 
4 255  TRP n 
4 256  THR n 
4 257  ALA n 
4 258  GLY n 
4 259  ALA n 
4 260  ALA n 
4 261  ALA n 
4 262  TYR n 
4 263  TYR n 
4 264  VAL n 
4 265  GLY n 
4 266  TYR n 
4 267  LEU n 
4 268  GLN n 
4 269  PRO n 
4 270  ARG n 
4 271  THR n 
4 272  PHE n 
4 273  LEU n 
4 274  LEU n 
4 275  LYS n 
4 276  TYR n 
4 277  ASN n 
4 278  GLU n 
4 279  ASN n 
4 280  GLY n 
4 281  THR n 
4 282  ILE n 
4 283  THR n 
4 284  ASP n 
4 285  ALA n 
4 286  VAL n 
4 287  ASP n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 215  ?                       ? ?      ? ? ? ? ? ? 'Homo sapiens' 9606    ? ? ? ? ? ? ? ? 
'Phaseolus vulgaris' 3885 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 240  ?                       ? ?      ? ? ? ? ? ? 'Homo sapiens' 9606    ? ? ? ? ? ? ? ? 
'Phaseolus vulgaris' 3885 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 1285 '2019-nCoV, SARS-CoV-2' ? 'S, 2' ? ? ? ? ? ? 
'Severe acute respiratory syndrome coronavirus 2' 2697049 ? ? ? ? ? ? ? ? 'Phaseolus vulgaris' 3885 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 287  ?                       ? ?      ? ? ? ? ? ? 'Homo sapiens' 9606    ? ? ? ? ? ? ? ? 
'Phaseolus vulgaris' 3885 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7EY4        7EY4   ? 1 ? 1 
2 PDB 7EY4        7EY4   ? 2 ? 1 
3 UNP SPIKE_SARS2 P0DTC2 ? 3 
;MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFD
NPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQT
LLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRV
QPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSF
VIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPC
NGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFL
PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGS
NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTI
SVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGF
NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAG
TITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALN
TLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRV
DFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNT
FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL
QELGKYE
;
1 
4 PDB 7EY4        7EY4   ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7EY4 L 1 ? 215  ? 7EY4   1 ? 215  ? 1 215  
2 2 7EY4 H 1 ? 240  ? 7EY4   1 ? 240  ? 1 240  
3 3 7EY4 R 1 ? 1204 ? P0DTC2 1 ? 1207 ? 4 1207 
4 4 7EY4 N 1 ? 287  ? 7EY4   1 ? 290  ? 1 290  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 7EY4 PHE R 18   ? UNP P0DTC2 LEU 18  conflict         21   1   
3 7EY4 ALA R 80   ? UNP P0DTC2 ASP 80  conflict         83   2   
3 7EY4 GLY R 215  ? UNP P0DTC2 ASP 215 conflict         218  3   
3 7EY4 ?   R ?    ? UNP P0DTC2 LEU 241 deletion         ?    4   
3 7EY4 ?   R ?    ? UNP P0DTC2 LEU 242 deletion         ?    5   
3 7EY4 ?   R ?    ? UNP P0DTC2 ALA 243 deletion         ?    6   
3 7EY4 ASN R 414  ? UNP P0DTC2 LYS 417 conflict         417  7   
3 7EY4 LYS R 481  ? UNP P0DTC2 GLU 484 conflict         484  8   
3 7EY4 TYR R 498  ? UNP P0DTC2 ASN 501 conflict         501  9   
3 7EY4 GLY R 611  ? UNP P0DTC2 ASP 614 conflict         614  10  
3 7EY4 GLY R 679  ? UNP P0DTC2 ARG 682 conflict         682  11  
3 7EY4 SER R 680  ? UNP P0DTC2 ARG 683 conflict         683  12  
3 7EY4 SER R 682  ? UNP P0DTC2 ARG 685 conflict         685  13  
3 7EY4 VAL R 698  ? UNP P0DTC2 ALA 701 conflict         701  14  
3 7EY4 PRO R 814  ? UNP P0DTC2 PHE 817 conflict         817  15  
3 7EY4 PRO R 889  ? UNP P0DTC2 ALA 892 conflict         892  16  
3 7EY4 PRO R 896  ? UNP P0DTC2 ALA 899 conflict         899  17  
3 7EY4 PRO R 939  ? UNP P0DTC2 ALA 942 conflict         942  18  
3 7EY4 PRO R 983  ? UNP P0DTC2 LYS 986 conflict         986  19  
3 7EY4 PRO R 984  ? UNP P0DTC2 VAL 987 conflict         987  20  
3 7EY4 GLN R 1205 ? UNP P0DTC2 ?   ?   'expression tag' 1208 21  
3 7EY4 GLY R 1206 ? UNP P0DTC2 ?   ?   'expression tag' 1209 22  
3 7EY4 SER R 1207 ? UNP P0DTC2 ?   ?   'expression tag' 1210 23  
3 7EY4 GLY R 1208 ? UNP P0DTC2 ?   ?   'expression tag' 1211 24  
3 7EY4 TYR R 1209 ? UNP P0DTC2 ?   ?   'expression tag' 1212 25  
3 7EY4 ILE R 1210 ? UNP P0DTC2 ?   ?   'expression tag' 1213 26  
3 7EY4 PRO R 1211 ? UNP P0DTC2 ?   ?   'expression tag' 1214 27  
3 7EY4 GLU R 1212 ? UNP P0DTC2 ?   ?   'expression tag' 1215 28  
3 7EY4 ALA R 1213 ? UNP P0DTC2 ?   ?   'expression tag' 1216 29  
3 7EY4 PRO R 1214 ? UNP P0DTC2 ?   ?   'expression tag' 1217 30  
3 7EY4 ARG R 1215 ? UNP P0DTC2 ?   ?   'expression tag' 1218 31  
3 7EY4 ASP R 1216 ? UNP P0DTC2 ?   ?   'expression tag' 1219 32  
3 7EY4 GLY R 1217 ? UNP P0DTC2 ?   ?   'expression tag' 1220 33  
3 7EY4 GLN R 1218 ? UNP P0DTC2 ?   ?   'expression tag' 1221 34  
3 7EY4 ALA R 1219 ? UNP P0DTC2 ?   ?   'expression tag' 1222 35  
3 7EY4 TYR R 1220 ? UNP P0DTC2 ?   ?   'expression tag' 1223 36  
3 7EY4 VAL R 1221 ? UNP P0DTC2 ?   ?   'expression tag' 1224 37  
3 7EY4 ARG R 1222 ? UNP P0DTC2 ?   ?   'expression tag' 1225 38  
3 7EY4 LYS R 1223 ? UNP P0DTC2 ?   ?   'expression tag' 1226 39  
3 7EY4 ASP R 1224 ? UNP P0DTC2 ?   ?   'expression tag' 1227 40  
3 7EY4 GLY R 1225 ? UNP P0DTC2 ?   ?   'expression tag' 1228 41  
3 7EY4 GLU R 1226 ? UNP P0DTC2 ?   ?   'expression tag' 1229 42  
3 7EY4 TRP R 1227 ? UNP P0DTC2 ?   ?   'expression tag' 1230 43  
3 7EY4 VAL R 1228 ? UNP P0DTC2 ?   ?   'expression tag' 1231 44  
3 7EY4 LEU R 1229 ? UNP P0DTC2 ?   ?   'expression tag' 1232 45  
3 7EY4 LEU R 1230 ? UNP P0DTC2 ?   ?   'expression tag' 1233 46  
3 7EY4 SER R 1231 ? UNP P0DTC2 ?   ?   'expression tag' 1234 47  
3 7EY4 THR R 1232 ? UNP P0DTC2 ?   ?   'expression tag' 1235 48  
3 7EY4 PHE R 1233 ? UNP P0DTC2 ?   ?   'expression tag' 1236 49  
3 7EY4 LEU R 1234 ? UNP P0DTC2 ?   ?   'expression tag' 1237 50  
3 7EY4 GLY R 1235 ? UNP P0DTC2 ?   ?   'expression tag' 1238 51  
3 7EY4 ARG R 1236 ? UNP P0DTC2 ?   ?   'expression tag' 1239 52  
3 7EY4 SER R 1237 ? UNP P0DTC2 ?   ?   'expression tag' 1240 53  
3 7EY4 LEU R 1238 ? UNP P0DTC2 ?   ?   'expression tag' 1241 54  
3 7EY4 GLU R 1239 ? UNP P0DTC2 ?   ?   'expression tag' 1242 55  
3 7EY4 VAL R 1240 ? UNP P0DTC2 ?   ?   'expression tag' 1243 56  
3 7EY4 LEU R 1241 ? UNP P0DTC2 ?   ?   'expression tag' 1244 57  
3 7EY4 PHE R 1242 ? UNP P0DTC2 ?   ?   'expression tag' 1245 58  
3 7EY4 GLN R 1243 ? UNP P0DTC2 ?   ?   'expression tag' 1246 59  
3 7EY4 GLY R 1244 ? UNP P0DTC2 ?   ?   'expression tag' 1247 60  
3 7EY4 PRO R 1245 ? UNP P0DTC2 ?   ?   'expression tag' 1248 61  
3 7EY4 GLY R 1246 ? UNP P0DTC2 ?   ?   'expression tag' 1249 62  
3 7EY4 HIS R 1247 ? UNP P0DTC2 ?   ?   'expression tag' 1250 63  
3 7EY4 HIS R 1248 ? UNP P0DTC2 ?   ?   'expression tag' 1251 64  
3 7EY4 HIS R 1249 ? UNP P0DTC2 ?   ?   'expression tag' 1252 65  
3 7EY4 HIS R 1250 ? UNP P0DTC2 ?   ?   'expression tag' 1253 66  
3 7EY4 HIS R 1251 ? UNP P0DTC2 ?   ?   'expression tag' 1254 67  
3 7EY4 HIS R 1252 ? UNP P0DTC2 ?   ?   'expression tag' 1255 68  
3 7EY4 HIS R 1253 ? UNP P0DTC2 ?   ?   'expression tag' 1256 69  
3 7EY4 HIS R 1254 ? UNP P0DTC2 ?   ?   'expression tag' 1257 70  
3 7EY4 SER R 1255 ? UNP P0DTC2 ?   ?   'expression tag' 1258 71  
3 7EY4 ALA R 1256 ? UNP P0DTC2 ?   ?   'expression tag' 1259 72  
3 7EY4 TRP R 1257 ? UNP P0DTC2 ?   ?   'expression tag' 1260 73  
3 7EY4 SER R 1258 ? UNP P0DTC2 ?   ?   'expression tag' 1261 74  
3 7EY4 HIS R 1259 ? UNP P0DTC2 ?   ?   'expression tag' 1262 75  
3 7EY4 PRO R 1260 ? UNP P0DTC2 ?   ?   'expression tag' 1263 76  
3 7EY4 GLN R 1261 ? UNP P0DTC2 ?   ?   'expression tag' 1264 77  
3 7EY4 PHE R 1262 ? UNP P0DTC2 ?   ?   'expression tag' 1265 78  
3 7EY4 GLU R 1263 ? UNP P0DTC2 ?   ?   'expression tag' 1266 79  
3 7EY4 LYS R 1264 ? UNP P0DTC2 ?   ?   'expression tag' 1267 80  
3 7EY4 GLY R 1265 ? UNP P0DTC2 ?   ?   'expression tag' 1268 81  
3 7EY4 GLY R 1266 ? UNP P0DTC2 ?   ?   'expression tag' 1269 82  
3 7EY4 GLY R 1267 ? UNP P0DTC2 ?   ?   'expression tag' 1270 83  
3 7EY4 SER R 1268 ? UNP P0DTC2 ?   ?   'expression tag' 1271 84  
3 7EY4 GLY R 1269 ? UNP P0DTC2 ?   ?   'expression tag' 1272 85  
3 7EY4 GLY R 1270 ? UNP P0DTC2 ?   ?   'expression tag' 1273 86  
3 7EY4 GLY R 1271 ? UNP P0DTC2 ?   ?   'expression tag' 1274 87  
3 7EY4 GLY R 1272 ? UNP P0DTC2 ?   ?   'expression tag' 1275 88  
3 7EY4 SER R 1273 ? UNP P0DTC2 ?   ?   'expression tag' 1276 89  
3 7EY4 GLY R 1274 ? UNP P0DTC2 ?   ?   'expression tag' 1277 90  
3 7EY4 GLY R 1275 ? UNP P0DTC2 ?   ?   'expression tag' 1278 91  
3 7EY4 SER R 1276 ? UNP P0DTC2 ?   ?   'expression tag' 1279 92  
3 7EY4 ALA R 1277 ? UNP P0DTC2 ?   ?   'expression tag' 1280 93  
3 7EY4 TRP R 1278 ? UNP P0DTC2 ?   ?   'expression tag' 1281 94  
3 7EY4 SER R 1279 ? UNP P0DTC2 ?   ?   'expression tag' 1282 95  
3 7EY4 HIS R 1280 ? UNP P0DTC2 ?   ?   'expression tag' 1283 96  
3 7EY4 PRO R 1281 ? UNP P0DTC2 ?   ?   'expression tag' 1284 97  
3 7EY4 GLN R 1282 ? UNP P0DTC2 ?   ?   'expression tag' 1285 98  
3 7EY4 PHE R 1283 ? UNP P0DTC2 ?   ?   'expression tag' 1286 99  
3 7EY4 GLU R 1284 ? UNP P0DTC2 ?   ?   'expression tag' 1287 100 
3 7EY4 LYS R 1285 ? UNP P0DTC2 ?   ?   'expression tag' 1288 101 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking' . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7EY4 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 7EY4 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.69 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.007  ? 3370 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.829  ? 4576 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 24.325 ? 472  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.051  ? 477  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005  ? 597  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     7EY4 
_struct.title                        'Local CryoEM of the SARS-CoV-2 S6PV2 in complex with BD-667' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7EY4 
_struct_keywords.text            'complex antibody, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ARG B 28  ? TYR B 32  ? ARG H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2 AA2 ASP B 74  ? GLU B 76  ? ASP H 74  GLU H 76  5 ? 3 
HELX_P HELX_P3 AA3 PHE C 335 ? ASN C 340 ? PHE R 338 ASN R 343 1 ? 6 
HELX_P HELX_P4 AA4 SER C 346 ? TRP C 350 ? SER R 349 TRP R 353 5 ? 5 
HELX_P HELX_P5 AA5 TYR C 362 ? ASN C 367 ? TYR R 365 ASN R 370 1 ? 6 
HELX_P HELX_P6 AA6 SER C 380 ? LEU C 384 ? SER R 383 LEU R 387 5 ? 5 
HELX_P HELX_P7 AA7 ASP C 402 ? ILE C 407 ? ASP R 405 ILE R 410 5 ? 6 
HELX_P HELX_P8 AA8 ASN C 414 ? ASN C 419 ? ASN R 417 ASN R 422 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 23  SG  ? ? ? 1_555 A CYS 88  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.039 ? ?               
disulf2 disulf ?    ? B CYS 22  SG  ? ? ? 1_555 B CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.042 ? ?               
disulf3 disulf ?    ? C CYS 333 SG  ? ? ? 1_555 C CYS 358 SG ? ? R CYS 336 R CYS 361 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf4 disulf ?    ? C CYS 376 SG  ? ? ? 1_555 C CYS 429 SG ? ? R CYS 379 R CYS 432 1_555 ? ? ? ? ? ? ? 2.042 ? ?               
disulf5 disulf ?    ? C CYS 477 SG  ? ? ? 1_555 C CYS 485 SG ? ? R CYS 480 R CYS 488 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf6 disulf ?    ? D CYS 131 SG  ? ? ? 1_555 D CYS 166 SG ? ? N CYS 131 N CYS 166 1_555 ? ? ? ? ? ? ? 2.047 ? ?               
covale1 covale one  ? D ASN 165 ND2 ? ? ? 1_555 E NAG .   C1 ? ? N ASN 165 A NAG 1   1_555 ? ? ? ? ? ? ? 1.462 ? N-Glycosylation 
covale2 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? A NAG 1   A NAG 2   1_555 ? ? ? ? ? ? ? 1.438 ? ?               
covale3 covale both ? E NAG .   O4  ? ? ? 1_555 E BMA .   C1 ? ? A NAG 2   A BMA 3   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4  ? 
AA2 ? 6  ? 
AA3 ? 4  ? 
AA4 ? 3  ? 
AA5 ? 4  ? 
AA6 ? 2  ? 
AA7 ? 5  ? 
AA8 ? 2  ? 
AA9 ? 2  ? 
AB1 ? 3  ? 
AB2 ? 13 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA2 1  2  ? parallel      
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA2 5  6  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA4 1  2  ? parallel      
AA4 2  3  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA5 3  4  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA7 1  2  ? anti-parallel 
AA7 2  3  ? anti-parallel 
AA7 3  4  ? anti-parallel 
AA7 4  5  ? anti-parallel 
AA8 1  2  ? anti-parallel 
AA9 1  2  ? anti-parallel 
AB1 1  2  ? anti-parallel 
AB1 2  3  ? anti-parallel 
AB2 1  13 ? anti-parallel 
AB2 2  12 ? anti-parallel 
AB2 3  9  ? anti-parallel 
AB2 3  13 ? anti-parallel 
AB2 4  5  ? anti-parallel 
AB2 4  12 ? anti-parallel 
AB2 5  6  ? anti-parallel 
AB2 6  7  ? anti-parallel 
AB2 6  8  ? anti-parallel 
AB2 9  10 ? anti-parallel 
AB2 10 11 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  MET A 4   ? THR A 5   ? MET L 4   THR L 5   
AA1 2  ALA A 19  ? ALA A 25  ? ALA L 19  ALA L 25  
AA1 3  GLU A 70  ? ILE A 75  ? GLU L 70  ILE L 75  
AA1 4  PHE A 62  ? PHE A 67  ? PHE L 62  PHE L 67  
AA2 1  THR A 10  ? VAL A 13  ? THR L 10  VAL L 13  
AA2 2  THR A 103 ? ILE A 107 ? THR L 103 ILE L 107 
AA2 3  VAL A 85  ? GLU A 90  ? VAL L 85  GLU L 90  
AA2 4  LEU A 33  ? GLN A 38  ? LEU L 33  GLN L 38  
AA2 5  ARG A 45  ? TYR A 49  ? ARG L 45  TYR L 49  
AA2 6  THR A 53  ? ARG A 54  ? THR L 53  ARG L 54  
AA3 1  GLN B 3   ? SER B 7   ? GLN H 3   SER H 7   
AA3 2  LEU B 18  ? SER B 25  ? LEU H 18  SER H 25  
AA3 3  SER B 78  ? MET B 83  ? SER H 78  MET H 83  
AA3 4  PHE B 68  ? ASP B 73  ? PHE H 68  ASP H 73  
AA4 1  LEU B 11  ? VAL B 12  ? LEU H 11  VAL H 12  
AA4 2  MET B 124 ? VAL B 127 ? MET H 124 VAL H 127 
AA4 3  ALA B 92  ? VAL B 93  ? ALA H 92  VAL H 93  
AA5 1  LEU B 45  ? TRP B 47  ? LEU H 45  TRP H 47  
AA5 2  TYR B 33  ? GLN B 39  ? TYR H 33  GLN H 39  
AA5 3  TYR B 95  ? GLY B 99  ? TYR H 95  GLY H 99  
AA5 4  PHE B 116 ? ASP B 117 ? PHE H 116 ASP H 117 
AA6 1  SER B 49  ? TYR B 50  ? SER H 49  TYR H 50  
AA6 2  TYR B 59  ? TYR B 60  ? TYR H 59  TYR H 60  
AA7 1  LYS C 353 ? ILE C 355 ? LYS R 356 ILE R 358 
AA7 2  VAL C 392 ? ARG C 400 ? VAL R 395 ARG R 403 
AA7 3  PRO C 504 ? PHE C 512 ? PRO R 507 PHE R 515 
AA7 4  GLY C 428 ? ASN C 434 ? GLY R 431 ASN R 437 
AA7 5  PHE C 374 ? TYR C 377 ? PHE R 377 TYR R 380 
AA8 1  LEU C 449 ? ARG C 451 ? LEU R 452 ARG R 454 
AA8 2  LEU C 489 ? SER C 491 ? LEU R 492 SER R 494 
AA9 1  TYR C 470 ? GLN C 471 ? TYR R 473 GLN R 474 
AA9 2  CYS C 485 ? TYR C 486 ? CYS R 488 TYR R 489 
AB1 1  SER D 50  ? PHE D 55  ? SER N 50  PHE N 55  
AB1 2  GLN D 268 ? LYS D 275 ? GLN N 271 LYS N 278 
AB1 3  ASP D 284 ? VAL D 286 ? ASP N 287 VAL N 289 
AB2 1  THR D 63  ? TRP D 64  ? THR N 63  TRP N 64  
AB2 2  LEU D 84  ? PRO D 85  ? LEU N 84  PRO N 85  
AB2 3  GLY D 89  ? THR D 95  ? GLY N 89  THR N 95  
AB2 4  GLY D 103 ? GLY D 107 ? GLY N 103 GLY N 107 
AB2 5  SER D 116 ? ASN D 121 ? SER N 116 ASN N 121 
AB2 6  VAL D 126 ? PHE D 133 ? VAL N 126 PHE N 133 
AB2 7  ALA D 163 ? ASN D 164 ? ALA N 163 ASN N 164 
AB2 8  GLU D 169 ? SER D 172 ? GLU N 169 SER N 172 
AB2 9  ARG D 190 ? ILE D 197 ? ARG N 190 ILE N 197 
AB2 10 TYR D 200 ? SER D 205 ? TYR N 200 SER N 205 
AB2 11 GLU D 224 ? LEU D 229 ? GLU N 224 LEU N 229 
AB2 12 ARG D 237 ? LEU D 241 ? ARG N 237 LEU N 241 
AB2 13 TYR D 263 ? TYR D 266 ? TYR N 266 TYR N 269 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N THR A 5   ? N THR L 5   O ARG A 24  ? O ARG L 24  
AA1 2  3  N ALA A 19  ? N ALA L 19  O ILE A 75  ? O ILE L 75  
AA1 3  4  O THR A 72  ? O THR L 72  N SER A 65  ? N SER L 65  
AA2 1  2  N LEU A 11  ? N LEU L 11  O GLU A 106 ? O GLU L 106 
AA2 2  3  O THR A 103 ? O THR L 103 N TYR A 86  ? N TYR L 86  
AA2 3  4  O VAL A 85  ? O VAL L 85  N GLN A 38  ? N GLN L 38  
AA2 4  5  N TRP A 35  ? N TRP L 35  O LEU A 47  ? O LEU L 47  
AA2 5  6  N TYR A 49  ? N TYR L 49  O THR A 53  ? O THR L 53  
AA3 1  2  N SER B 7   ? N SER H 7   O SER B 21  ? O SER H 21  
AA3 2  3  N LEU B 20  ? N LEU H 20  O LEU B 81  ? O LEU H 81  
AA3 3  4  O GLN B 82  ? O GLN H 82  N THR B 69  ? N THR H 69  
AA4 1  2  N VAL B 12  ? N VAL H 12  O THR B 126 ? O THR H 126 
AA4 2  3  O VAL B 125 ? O VAL H 125 N ALA B 92  ? N ALA H 92  
AA5 1  2  O GLU B 46  ? O GLU H 46  N ARG B 38  ? N ARG H 38  
AA5 2  3  N ASN B 35  ? N ASN H 35  O ALA B 97  ? O ALA H 97  
AA5 3  4  N ARG B 98  ? N ARG H 98  O ASP B 117 ? O ASP H 117 
AA6 1  2  N TYR B 50  ? N TYR H 50  O TYR B 59  ? O TYR H 59  
AA7 1  2  N ILE C 355 ? N ILE R 358 O VAL C 392 ? O VAL R 395 
AA7 2  3  N ILE C 399 ? N ILE R 402 O TYR C 505 ? O TYR R 508 
AA7 3  4  O VAL C 508 ? O VAL R 511 N ILE C 431 ? N ILE R 434 
AA7 4  5  O VAL C 430 ? O VAL R 433 N LYS C 375 ? N LYS R 378 
AA8 1  2  N TYR C 450 ? N TYR R 453 O GLN C 490 ? O GLN R 493 
AA9 1  2  N TYR C 470 ? N TYR R 473 O TYR C 486 ? O TYR R 489 
AB1 1  2  N PHE D 55  ? N PHE N 55  O GLN D 268 ? O GLN N 271 
AB1 2  3  N LYS D 275 ? N LYS N 278 O ASP D 284 ? O ASP N 287 
AB2 1  13 N THR D 63  ? N THR N 63  O VAL D 264 ? O VAL N 267 
AB2 2  12 N LEU D 84  ? N LEU N 84  O PHE D 238 ? O PHE N 238 
AB2 3  9  N PHE D 92  ? N PHE N 92  O PHE D 192 ? O PHE N 192 
AB2 3  13 N ALA D 93  ? N ALA N 93  O TYR D 263 ? O TYR N 266 
AB2 4  5  N TRP D 104 ? N TRP N 104 O ILE D 119 ? O ILE N 119 
AB2 4  12 N GLY D 107 ? N GLY N 107 O ARG D 237 ? O ARG N 237 
AB2 5  6  N VAL D 120 ? N VAL N 120 O VAL D 127 ? O VAL N 127 
AB2 6  7  N GLU D 132 ? N GLU N 132 O ASN D 164 ? O ASN N 164 
AB2 6  8  N VAL D 126 ? N VAL N 126 O SER D 172 ? O SER N 172 
AB2 9  10 N LYS D 195 ? N LYS N 195 O LYS D 202 ? O LYS N 202 
AB2 10 11 N PHE D 201 ? N PHE N 201 O LEU D 229 ? O LEU N 229 
# 
_atom_sites.entry_id                    7EY4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 1   ? 250.131 175.717 154.120 1.00 92.13  ? 1   GLU L N   1 
ATOM   2    C CA  . GLU A 1 1   ? 250.613 174.355 154.307 1.00 92.13  ? 1   GLU L CA  1 
ATOM   3    C C   . GLU A 1 1   ? 250.801 174.053 155.785 1.00 92.13  ? 1   GLU L C   1 
ATOM   4    O O   . GLU A 1 1   ? 251.891 174.216 156.330 1.00 92.13  ? 1   GLU L O   1 
ATOM   5    C CB  . GLU A 1 1   ? 251.923 174.139 153.552 1.00 92.13  ? 1   GLU L CB  1 
ATOM   6    C CG  . GLU A 1 1   ? 252.425 172.708 153.581 1.00 92.13  ? 1   GLU L CG  1 
ATOM   7    C CD  . GLU A 1 1   ? 253.716 172.534 152.810 1.00 92.13  ? 1   GLU L CD  1 
ATOM   8    O OE1 . GLU A 1 1   ? 254.128 173.486 152.115 1.00 92.13  ? 1   GLU L OE1 1 
ATOM   9    O OE2 . GLU A 1 1   ? 254.323 171.446 152.903 1.00 92.13  ? 1   GLU L OE2 1 
ATOM   10   N N   . ILE A 1 2   ? 249.727 173.616 156.428 1.00 67.88  ? 2   ILE L N   1 
ATOM   11   C CA  . ILE A 1 2   ? 249.729 173.283 157.845 1.00 67.88  ? 2   ILE L CA  1 
ATOM   12   C C   . ILE A 1 2   ? 249.784 171.768 157.950 1.00 67.88  ? 2   ILE L C   1 
ATOM   13   O O   . ILE A 1 2   ? 248.767 171.089 157.774 1.00 67.88  ? 2   ILE L O   1 
ATOM   14   C CB  . ILE A 1 2   ? 248.496 173.844 158.559 1.00 67.88  ? 2   ILE L CB  1 
ATOM   15   C CG1 . ILE A 1 2   ? 248.498 175.368 158.487 1.00 67.88  ? 2   ILE L CG1 1 
ATOM   16   C CG2 . ILE A 1 2   ? 248.468 173.384 159.998 1.00 67.88  ? 2   ILE L CG2 1 
ATOM   17   C CD1 . ILE A 1 2   ? 247.228 175.999 158.995 1.00 67.88  ? 2   ILE L CD1 1 
ATOM   18   N N   . VAL A 1 3   ? 250.961 171.231 158.243 1.00 66.40  ? 3   VAL L N   1 
ATOM   19   C CA  . VAL A 1 3   ? 251.163 169.789 158.273 1.00 66.40  ? 3   VAL L CA  1 
ATOM   20   C C   . VAL A 1 3   ? 250.568 169.254 159.569 1.00 66.40  ? 3   VAL L C   1 
ATOM   21   O O   . VAL A 1 3   ? 251.003 169.624 160.661 1.00 66.40  ? 3   VAL L O   1 
ATOM   22   C CB  . VAL A 1 3   ? 252.646 169.430 158.153 1.00 66.40  ? 3   VAL L CB  1 
ATOM   23   C CG1 . VAL A 1 3   ? 252.842 167.944 158.362 1.00 66.40  ? 3   VAL L CG1 1 
ATOM   24   C CG2 . VAL A 1 3   ? 253.175 169.851 156.799 1.00 66.40  ? 3   VAL L CG2 1 
ATOM   25   N N   . MET A 1 4   ? 249.573 168.381 159.447 1.00 66.11  ? 4   MET L N   1 
ATOM   26   C CA  . MET A 1 4   ? 248.941 167.760 160.600 1.00 66.11  ? 4   MET L CA  1 
ATOM   27   C C   . MET A 1 4   ? 249.478 166.350 160.791 1.00 66.11  ? 4   MET L C   1 
ATOM   28   O O   . MET A 1 4   ? 249.611 165.583 159.836 1.00 66.11  ? 4   MET L O   1 
ATOM   29   C CB  . MET A 1 4   ? 247.425 167.707 160.428 1.00 66.11  ? 4   MET L CB  1 
ATOM   30   C CG  . MET A 1 4   ? 246.815 168.994 159.946 1.00 66.11  ? 4   MET L CG  1 
ATOM   31   S SD  . MET A 1 4   ? 246.356 170.097 161.280 1.00 66.11  ? 4   MET L SD  1 
ATOM   32   C CE  . MET A 1 4   ? 245.246 169.042 162.185 1.00 66.11  ? 4   MET L CE  1 
ATOM   33   N N   . THR A 1 5   ? 249.798 166.016 162.038 1.00 65.05  ? 5   THR L N   1 
ATOM   34   C CA  . THR A 1 5   ? 250.239 164.672 162.388 1.00 65.05  ? 5   THR L CA  1 
ATOM   35   C C   . THR A 1 5   ? 249.448 164.198 163.592 1.00 65.05  ? 5   THR L C   1 
ATOM   36   O O   . THR A 1 5   ? 249.270 164.951 164.553 1.00 65.05  ? 5   THR L O   1 
ATOM   37   C CB  . THR A 1 5   ? 251.736 164.627 162.704 1.00 65.05  ? 5   THR L CB  1 
ATOM   38   O OG1 . THR A 1 5   ? 252.009 165.468 163.830 1.00 65.05  ? 5   THR L OG1 1 
ATOM   39   C CG2 . THR A 1 5   ? 252.551 165.097 161.514 1.00 65.05  ? 5   THR L CG2 1 
ATOM   40   N N   . GLN A 1 6   ? 248.974 162.956 163.537 1.00 60.21  ? 6   GLN L N   1 
ATOM   41   C CA  . GLN A 1 6   ? 248.224 162.385 164.647 1.00 60.21  ? 6   GLN L CA  1 
ATOM   42   C C   . GLN A 1 6   ? 249.147 161.592 165.563 1.00 60.21  ? 6   GLN L C   1 
ATOM   43   O O   . GLN A 1 6   ? 249.326 161.929 166.738 1.00 60.21  ? 6   GLN L O   1 
ATOM   44   C CB  . GLN A 1 6   ? 247.107 161.492 164.116 1.00 60.21  ? 6   GLN L CB  1 
ATOM   45   C CG  . GLN A 1 6   ? 245.839 162.241 163.809 1.00 60.21  ? 6   GLN L CG  1 
ATOM   46   C CD  . GLN A 1 6   ? 244.660 161.324 163.633 1.00 60.21  ? 6   GLN L CD  1 
ATOM   47   O OE1 . GLN A 1 6   ? 244.549 160.627 162.631 1.00 60.21  ? 6   GLN L OE1 1 
ATOM   48   N NE2 . GLN A 1 6   ? 243.767 161.320 164.610 1.00 60.21  ? 6   GLN L NE2 1 
ATOM   49   N N   . SER A 1 7   ? 249.731 160.538 165.016 1.00 72.50  ? 7   SER L N   1 
ATOM   50   C CA  . SER A 1 7   ? 250.795 159.720 165.587 1.00 72.50  ? 7   SER L CA  1 
ATOM   51   C C   . SER A 1 7   ? 250.527 159.065 166.943 1.00 72.50  ? 7   SER L C   1 
ATOM   52   O O   . SER A 1 7   ? 251.406 159.096 167.811 1.00 72.50  ? 7   SER L O   1 
ATOM   53   C CB  . SER A 1 7   ? 252.064 160.568 165.698 1.00 72.50  ? 7   SER L CB  1 
ATOM   54   O OG  . SER A 1 7   ? 253.130 159.823 166.258 1.00 72.50  ? 7   SER L OG  1 
ATOM   55   N N   . PRO A 1 8   ? 249.355 158.482 167.186 1.00 74.38  ? 8   PRO L N   1 
ATOM   56   C CA  . PRO A 1 8   ? 249.332 157.145 167.781 1.00 74.38  ? 8   PRO L CA  1 
ATOM   57   C C   . PRO A 1 8   ? 249.211 156.124 166.665 1.00 74.38  ? 8   PRO L C   1 
ATOM   58   O O   . PRO A 1 8   ? 248.302 156.183 165.835 1.00 74.38  ? 8   PRO L O   1 
ATOM   59   C CB  . PRO A 1 8   ? 248.088 157.164 168.675 1.00 74.38  ? 8   PRO L CB  1 
ATOM   60   C CG  . PRO A 1 8   ? 247.196 158.132 168.040 1.00 74.38  ? 8   PRO L CG  1 
ATOM   61   C CD  . PRO A 1 8   ? 248.059 159.162 167.357 1.00 74.38  ? 8   PRO L CD  1 
ATOM   62   N N   . ALA A 1 9   ? 250.149 155.181 166.642 1.00 83.62  ? 9   ALA L N   1 
ATOM   63   C CA  . ALA A 1 9   ? 250.269 154.339 165.456 1.00 83.62  ? 9   ALA L CA  1 
ATOM   64   C C   . ALA A 1 9   ? 249.050 153.446 165.268 1.00 83.62  ? 9   ALA L C   1 
ATOM   65   O O   . ALA A 1 9   ? 248.333 153.573 164.269 1.00 83.62  ? 9   ALA L O   1 
ATOM   66   C CB  . ALA A 1 9   ? 251.540 153.494 165.540 1.00 83.62  ? 9   ALA L CB  1 
ATOM   67   N N   . THR A 1 10  ? 248.794 152.547 166.214 1.00 87.87  ? 10  THR L N   1 
ATOM   68   C CA  . THR A 1 10  ? 247.634 151.662 166.157 1.00 87.87  ? 10  THR L CA  1 
ATOM   69   C C   . THR A 1 10  ? 247.117 151.509 167.578 1.00 87.87  ? 10  THR L C   1 
ATOM   70   O O   . THR A 1 10  ? 247.709 150.771 168.371 1.00 87.87  ? 10  THR L O   1 
ATOM   71   C CB  . THR A 1 10  ? 247.985 150.294 165.569 1.00 87.87  ? 10  THR L CB  1 
ATOM   72   O OG1 . THR A 1 10  ? 248.681 149.519 166.553 1.00 87.87  ? 10  THR L OG1 1 
ATOM   73   C CG2 . THR A 1 10  ? 248.849 150.408 164.318 1.00 87.87  ? 10  THR L CG2 1 
ATOM   74   N N   . LEU A 1 11  ? 246.026 152.192 167.903 1.00 79.44  ? 11  LEU L N   1 
ATOM   75   C CA  . LEU A 1 11  ? 245.453 152.073 169.233 1.00 79.44  ? 11  LEU L CA  1 
ATOM   76   C C   . LEU A 1 11  ? 244.866 150.681 169.425 1.00 79.44  ? 11  LEU L C   1 
ATOM   77   O O   . LEU A 1 11  ? 244.168 150.153 168.556 1.00 79.44  ? 11  LEU L O   1 
ATOM   78   C CB  . LEU A 1 11  ? 244.379 153.133 169.454 1.00 79.44  ? 11  LEU L CB  1 
ATOM   79   C CG  . LEU A 1 11  ? 243.958 153.320 170.906 1.00 79.44  ? 11  LEU L CG  1 
ATOM   80   C CD1 . LEU A 1 11  ? 245.155 153.753 171.717 1.00 79.44  ? 11  LEU L CD1 1 
ATOM   81   C CD2 . LEU A 1 11  ? 242.858 154.350 171.008 1.00 79.44  ? 11  LEU L CD2 1 
ATOM   82   N N   . SER A 1 12  ? 245.163 150.082 170.580 1.00 89.55  ? 12  SER L N   1 
ATOM   83   C CA  . SER A 1 12  ? 244.805 148.692 170.874 1.00 89.55  ? 12  SER L CA  1 
ATOM   84   C C   . SER A 1 12  ? 244.109 148.662 172.230 1.00 89.55  ? 12  SER L C   1 
ATOM   85   O O   . SER A 1 12  ? 244.760 148.561 173.271 1.00 89.55  ? 12  SER L O   1 
ATOM   86   C CB  . SER A 1 12  ? 246.044 147.803 170.853 1.00 89.55  ? 12  SER L CB  1 
ATOM   87   O OG  . SER A 1 12  ? 246.820 148.036 169.691 1.00 89.55  ? 12  SER L OG  1 
ATOM   88   N N   . VAL A 1 13  ? 242.783 148.747 172.220 1.00 84.33  ? 13  VAL L N   1 
ATOM   89   C CA  . VAL A 1 13  ? 241.994 148.828 173.443 1.00 84.33  ? 13  VAL L CA  1 
ATOM   90   C C   . VAL A 1 13  ? 240.847 147.832 173.370 1.00 84.33  ? 13  VAL L C   1 
ATOM   91   O O   . VAL A 1 13  ? 240.273 147.612 172.298 1.00 84.33  ? 13  VAL L O   1 
ATOM   92   C CB  . VAL A 1 13  ? 241.469 150.254 173.687 1.00 84.33  ? 13  VAL L CB  1 
ATOM   93   C CG1 . VAL A 1 13  ? 242.626 151.218 173.865 1.00 84.33  ? 13  VAL L CG1 1 
ATOM   94   C CG2 . VAL A 1 13  ? 240.608 150.697 172.530 1.00 84.33  ? 13  VAL L CG2 1 
ATOM   95   N N   . SER A 1 14  ? 240.534 147.219 174.510 1.00 84.22  ? 14  SER L N   1 
ATOM   96   C CA  . SER A 1 14  ? 239.417 146.299 174.617 1.00 84.22  ? 14  SER L CA  1 
ATOM   97   C C   . SER A 1 14  ? 238.101 147.067 174.738 1.00 84.22  ? 14  SER L C   1 
ATOM   98   O O   . SER A 1 14  ? 238.090 148.241 175.113 1.00 84.22  ? 14  SER L O   1 
ATOM   99   C CB  . SER A 1 14  ? 239.610 145.386 175.824 1.00 84.22  ? 14  SER L CB  1 
ATOM   100  O OG  . SER A 1 14  ? 240.747 144.560 175.658 1.00 84.22  ? 14  SER L OG  1 
ATOM   101  N N   . PRO A 1 15  ? 236.976 146.425 174.423 1.00 84.61  ? 15  PRO L N   1 
ATOM   102  C CA  . PRO A 1 15  ? 235.687 147.116 174.523 1.00 84.61  ? 15  PRO L CA  1 
ATOM   103  C C   . PRO A 1 15  ? 235.351 147.495 175.955 1.00 84.61  ? 15  PRO L C   1 
ATOM   104  O O   . PRO A 1 15  ? 235.770 146.844 176.913 1.00 84.61  ? 15  PRO L O   1 
ATOM   105  C CB  . PRO A 1 15  ? 234.688 146.091 173.973 1.00 84.61  ? 15  PRO L CB  1 
ATOM   106  C CG  . PRO A 1 15  ? 235.365 144.782 174.123 1.00 84.61  ? 15  PRO L CG  1 
ATOM   107  C CD  . PRO A 1 15  ? 236.820 145.051 173.917 1.00 84.61  ? 15  PRO L CD  1 
ATOM   108  N N   . GLY A 1 16  ? 234.579 148.572 176.088 1.00 82.44  ? 16  GLY L N   1 
ATOM   109  C CA  . GLY A 1 16  ? 234.192 149.091 177.381 1.00 82.44  ? 16  GLY L CA  1 
ATOM   110  C C   . GLY A 1 16  ? 235.188 150.030 178.022 1.00 82.44  ? 16  GLY L C   1 
ATOM   111  O O   . GLY A 1 16  ? 235.003 150.399 179.188 1.00 82.44  ? 16  GLY L O   1 
ATOM   112  N N   . GLU A 1 17  ? 236.228 150.432 177.305 1.00 82.43  ? 17  GLU L N   1 
ATOM   113  C CA  . GLU A 1 17  ? 237.290 151.261 177.849 1.00 82.43  ? 17  GLU L CA  1 
ATOM   114  C C   . GLU A 1 17  ? 237.193 152.670 177.265 1.00 82.43  ? 17  GLU L C   1 
ATOM   115  O O   . GLU A 1 17  ? 236.546 152.898 176.239 1.00 82.43  ? 17  GLU L O   1 
ATOM   116  C CB  . GLU A 1 17  ? 238.647 150.606 177.552 1.00 82.43  ? 17  GLU L CB  1 
ATOM   117  C CG  . GLU A 1 17  ? 239.749 150.835 178.583 1.00 82.43  ? 17  GLU L CG  1 
ATOM   118  C CD  . GLU A 1 17  ? 240.348 152.217 178.535 1.00 82.43  ? 17  GLU L CD  1 
ATOM   119  O OE1 . GLU A 1 17  ? 240.213 152.876 177.490 1.00 82.43  ? 17  GLU L OE1 1 
ATOM   120  O OE2 . GLU A 1 17  ? 240.950 152.646 179.541 1.00 82.43  ? 17  GLU L OE2 1 
ATOM   121  N N   . ARG A 1 18  ? 237.820 153.626 177.949 1.00 82.02  ? 18  ARG L N   1 
ATOM   122  C CA  . ARG A 1 18  ? 237.758 155.039 177.579 1.00 82.02  ? 18  ARG L CA  1 
ATOM   123  C C   . ARG A 1 18  ? 239.092 155.454 176.967 1.00 82.02  ? 18  ARG L C   1 
ATOM   124  O O   . ARG A 1 18  ? 240.074 155.662 177.686 1.00 82.02  ? 18  ARG L O   1 
ATOM   125  C CB  . ARG A 1 18  ? 237.424 155.900 178.796 1.00 82.02  ? 18  ARG L CB  1 
ATOM   126  C CG  . ARG A 1 18  ? 237.449 157.393 178.532 1.00 82.02  ? 18  ARG L CG  1 
ATOM   127  C CD  . ARG A 1 18  ? 236.801 158.161 179.666 1.00 82.02  ? 18  ARG L CD  1 
ATOM   128  N NE  . ARG A 1 18  ? 236.747 159.593 179.397 1.00 82.02  ? 18  ARG L NE  1 
ATOM   129  C CZ  . ARG A 1 18  ? 236.258 160.494 180.243 1.00 82.02  ? 18  ARG L CZ  1 
ATOM   130  N NH1 . ARG A 1 18  ? 236.249 161.779 179.916 1.00 82.02  ? 18  ARG L NH1 1 
ATOM   131  N NH2 . ARG A 1 18  ? 235.773 160.112 181.417 1.00 82.02  ? 18  ARG L NH2 1 
ATOM   132  N N   . ALA A 1 19  ? 239.125 155.583 175.643 1.00 73.01  ? 19  ALA L N   1 
ATOM   133  C CA  . ALA A 1 19  ? 240.354 155.842 174.909 1.00 73.01  ? 19  ALA L CA  1 
ATOM   134  C C   . ALA A 1 19  ? 240.390 157.276 174.398 1.00 73.01  ? 19  ALA L C   1 
ATOM   135  O O   . ALA A 1 19  ? 239.350 157.907 174.191 1.00 73.01  ? 19  ALA L O   1 
ATOM   136  C CB  . ALA A 1 19  ? 240.505 154.873 173.735 1.00 73.01  ? 19  ALA L CB  1 
ATOM   137  N N   . THR A 1 20  ? 241.606 157.781 174.192 1.00 66.18  ? 20  THR L N   1 
ATOM   138  C CA  . THR A 1 20  ? 241.833 159.140 173.722 1.00 66.18  ? 20  THR L CA  1 
ATOM   139  C C   . THR A 1 20  ? 242.690 159.117 172.465 1.00 66.18  ? 20  THR L C   1 
ATOM   140  O O   . THR A 1 20  ? 243.479 158.195 172.250 1.00 66.18  ? 20  THR L O   1 
ATOM   141  C CB  . THR A 1 20  ? 242.524 160.004 174.782 1.00 66.18  ? 20  THR L CB  1 
ATOM   142  O OG1 . THR A 1 20  ? 243.933 159.749 174.759 1.00 66.18  ? 20  THR L OG1 1 
ATOM   143  C CG2 . THR A 1 20  ? 241.980 159.698 176.168 1.00 66.18  ? 20  THR L CG2 1 
ATOM   144  N N   . LEU A 1 21  ? 242.531 160.149 171.638 1.00 57.43  ? 21  LEU L N   1 
ATOM   145  C CA  . LEU A 1 21  ? 243.260 160.274 170.385 1.00 57.43  ? 21  LEU L CA  1 
ATOM   146  C C   . LEU A 1 21  ? 243.864 161.667 170.285 1.00 57.43  ? 21  LEU L C   1 
ATOM   147  O O   . LEU A 1 21  ? 243.328 162.629 170.837 1.00 57.43  ? 21  LEU L O   1 
ATOM   148  C CB  . LEU A 1 21  ? 242.350 160.010 169.184 1.00 57.43  ? 21  LEU L CB  1 
ATOM   149  C CG  . LEU A 1 21  ? 241.788 158.595 169.061 1.00 57.43  ? 21  LEU L CG  1 
ATOM   150  C CD1 . LEU A 1 21  ? 240.682 158.556 168.031 1.00 57.43  ? 21  LEU L CD1 1 
ATOM   151  C CD2 . LEU A 1 21  ? 242.885 157.621 168.698 1.00 57.43  ? 21  LEU L CD2 1 
ATOM   152  N N   . SER A 1 22  ? 244.978 161.770 169.566 1.00 59.80  ? 22  SER L N   1 
ATOM   153  C CA  . SER A 1 22  ? 245.758 162.998 169.498 1.00 59.80  ? 22  SER L CA  1 
ATOM   154  C C   . SER A 1 22  ? 245.896 163.471 168.060 1.00 59.80  ? 22  SER L C   1 
ATOM   155  O O   . SER A 1 22  ? 246.125 162.666 167.154 1.00 59.80  ? 22  SER L O   1 
ATOM   156  C CB  . SER A 1 22  ? 247.148 162.791 170.087 1.00 59.80  ? 22  SER L CB  1 
ATOM   157  O OG  . SER A 1 22  ? 247.998 162.168 169.139 1.00 59.80  ? 22  SER L OG  1 
ATOM   158  N N   . CYS A 1 23  ? 245.781 164.783 167.859 1.00 56.32  ? 23  CYS L N   1 
ATOM   159  C CA  . CYS A 1 23  ? 245.943 165.383 166.536 1.00 56.32  ? 23  CYS L CA  1 
ATOM   160  C C   . CYS A 1 23  ? 246.656 166.711 166.729 1.00 56.32  ? 23  CYS L C   1 
ATOM   161  O O   . CYS A 1 23  ? 246.039 167.688 167.160 1.00 56.32  ? 23  CYS L O   1 
ATOM   162  C CB  . CYS A 1 23  ? 244.592 165.565 165.842 1.00 56.32  ? 23  CYS L CB  1 
ATOM   163  S SG  . CYS A 1 23  ? 244.612 166.355 164.205 1.00 56.32  ? 23  CYS L SG  1 
ATOM   164  N N   . ARG A 1 24  ? 247.948 166.741 166.415 1.00 66.87  ? 24  ARG L N   1 
ATOM   165  C CA  . ARG A 1 24  ? 248.816 167.881 166.680 1.00 66.87  ? 24  ARG L CA  1 
ATOM   166  C C   . ARG A 1 24  ? 249.072 168.654 165.396 1.00 66.87  ? 24  ARG L C   1 
ATOM   167  O O   . ARG A 1 24  ? 249.552 168.084 164.412 1.00 66.87  ? 24  ARG L O   1 
ATOM   168  C CB  . ARG A 1 24  ? 250.147 167.419 167.270 1.00 66.87  ? 24  ARG L CB  1 
ATOM   169  C CG  . ARG A 1 24  ? 251.087 168.542 167.666 1.00 66.87  ? 24  ARG L CG  1 
ATOM   170  C CD  . ARG A 1 24  ? 251.629 168.338 169.070 1.00 66.87  ? 24  ARG L CD  1 
ATOM   171  N NE  . ARG A 1 24  ? 251.963 166.941 169.337 1.00 66.87  ? 24  ARG L NE  1 
ATOM   172  C CZ  . ARG A 1 24  ? 252.990 166.292 168.795 1.00 66.87  ? 24  ARG L CZ  1 
ATOM   173  N NH1 . ARG A 1 24  ? 253.805 166.910 167.951 1.00 66.87  ? 24  ARG L NH1 1 
ATOM   174  N NH2 . ARG A 1 24  ? 253.206 165.021 169.101 1.00 66.87  ? 24  ARG L NH2 1 
ATOM   175  N N   . ALA A 1 25  ? 248.780 169.950 165.418 1.00 63.56  ? 25  ALA L N   1 
ATOM   176  C CA  . ALA A 1 25  ? 248.965 170.812 164.261 1.00 63.56  ? 25  ALA L CA  1 
ATOM   177  C C   . ALA A 1 25  ? 250.282 171.565 164.373 1.00 63.56  ? 25  ALA L C   1 
ATOM   178  O O   . ALA A 1 25  ? 250.745 171.864 165.477 1.00 63.56  ? 25  ALA L O   1 
ATOM   179  C CB  . ALA A 1 25  ? 247.810 171.804 164.130 1.00 63.56  ? 25  ALA L CB  1 
ATOM   180  N N   . SER A 1 26  ? 250.887 171.864 163.223 1.00 68.47  ? 26  SER L N   1 
ATOM   181  C CA  . SER A 1 26  ? 252.159 172.580 163.227 1.00 68.47  ? 26  SER L CA  1 
ATOM   182  C C   . SER A 1 26  ? 251.977 174.062 163.526 1.00 68.47  ? 26  SER L C   1 
ATOM   183  O O   . SER A 1 26  ? 252.875 174.691 164.095 1.00 68.47  ? 26  SER L O   1 
ATOM   184  C CB  . SER A 1 26  ? 252.873 172.395 161.891 1.00 68.47  ? 26  SER L CB  1 
ATOM   185  O OG  . SER A 1 26  ? 254.046 173.183 161.836 1.00 68.47  ? 26  SER L OG  1 
ATOM   186  N N   . GLN A 1 27  ? 250.842 174.635 163.151 1.00 64.69  ? 27  GLN L N   1 
ATOM   187  C CA  . GLN A 1 27  ? 250.560 176.051 163.334 1.00 64.69  ? 27  GLN L CA  1 
ATOM   188  C C   . GLN A 1 27  ? 249.335 176.225 164.224 1.00 64.69  ? 27  GLN L C   1 
ATOM   189  O O   . GLN A 1 27  ? 248.847 175.280 164.843 1.00 64.69  ? 27  GLN L O   1 
ATOM   190  C CB  . GLN A 1 27  ? 250.354 176.744 161.988 1.00 64.69  ? 27  GLN L CB  1 
ATOM   191  C CG  . GLN A 1 27  ? 251.524 176.600 161.046 1.00 64.69  ? 27  GLN L CG  1 
ATOM   192  C CD  . GLN A 1 27  ? 251.564 177.705 160.021 1.00 64.69  ? 27  GLN L CD  1 
ATOM   193  O OE1 . GLN A 1 27  ? 250.706 178.586 160.012 1.00 64.69  ? 27  GLN L OE1 1 
ATOM   194  N NE2 . GLN A 1 27  ? 252.563 177.670 159.149 1.00 64.69  ? 27  GLN L NE2 1 
ATOM   195  N N   . SER A 1 28  ? 248.849 177.458 164.295 1.00 57.65  ? 28  SER L N   1 
ATOM   196  C CA  . SER A 1 28  ? 247.677 177.780 165.093 1.00 57.65  ? 28  SER L CA  1 
ATOM   197  C C   . SER A 1 28  ? 246.466 177.902 164.182 1.00 57.65  ? 28  SER L C   1 
ATOM   198  O O   . SER A 1 28  ? 246.438 178.758 163.293 1.00 57.65  ? 28  SER L O   1 
ATOM   199  C CB  . SER A 1 28  ? 247.888 179.082 165.858 1.00 57.65  ? 28  SER L CB  1 
ATOM   200  O OG  . SER A 1 28  ? 247.969 180.174 164.961 1.00 57.65  ? 28  SER L OG  1 
ATOM   201  N N   . VAL A 1 29  ? 245.467 177.055 164.406 1.00 43.80  ? 29  VAL L N   1 
ATOM   202  C CA  . VAL A 1 29  ? 244.202 177.141 163.691 1.00 43.80  ? 29  VAL L CA  1 
ATOM   203  C C   . VAL A 1 29  ? 243.139 177.544 164.703 1.00 43.80  ? 29  VAL L C   1 
ATOM   204  O O   . VAL A 1 29  ? 242.273 178.379 164.428 1.00 43.80  ? 29  VAL L O   1 
ATOM   205  C CB  . VAL A 1 29  ? 243.883 175.811 162.988 1.00 43.80  ? 29  VAL L CB  1 
ATOM   206  C CG1 . VAL A 1 29  ? 244.756 175.660 161.777 1.00 43.80  ? 29  VAL L CG1 1 
ATOM   207  C CG2 . VAL A 1 29  ? 244.154 174.657 163.909 1.00 43.80  ? 29  VAL L CG2 1 
ATOM   208  N N   . SER A 1 30  ? 243.210 176.933 165.877 1.00 54.54  ? 30  SER L N   1 
ATOM   209  C CA  . SER A 1 30  ? 242.652 177.419 167.133 1.00 54.54  ? 30  SER L CA  1 
ATOM   210  C C   . SER A 1 30  ? 241.148 177.281 167.306 1.00 54.54  ? 30  SER L C   1 
ATOM   211  O O   . SER A 1 30  ? 240.656 177.364 168.435 1.00 54.54  ? 30  SER L O   1 
ATOM   212  C CB  . SER A 1 30  ? 243.012 178.895 167.299 1.00 54.54  ? 30  SER L CB  1 
ATOM   213  O OG  . SER A 1 30  ? 242.133 179.700 166.531 1.00 54.54  ? 30  SER L OG  1 
ATOM   214  N N   . ARG A 1 31  ? 240.408 177.067 166.252 1.00 50.79  ? 31  ARG L N   1 
ATOM   215  C CA  . ARG A 1 31  ? 239.050 176.580 166.441 1.00 50.79  ? 31  ARG L CA  1 
ATOM   216  C C   . ARG A 1 31  ? 238.562 175.746 165.271 1.00 50.79  ? 31  ARG L C   1 
ATOM   217  O O   . ARG A 1 31  ? 237.419 175.285 165.303 1.00 50.79  ? 31  ARG L O   1 
ATOM   218  C CB  . ARG A 1 31  ? 238.095 177.757 166.706 1.00 50.79  ? 31  ARG L CB  1 
ATOM   219  C CG  . ARG A 1 31  ? 236.803 177.368 167.413 1.00 50.79  ? 31  ARG L CG  1 
ATOM   220  C CD  . ARG A 1 31  ? 236.015 178.585 167.859 1.00 50.79  ? 31  ARG L CD  1 
ATOM   221  N NE  . ARG A 1 31  ? 236.637 179.236 169.008 1.00 50.79  ? 31  ARG L NE  1 
ATOM   222  C CZ  . ARG A 1 31  ? 236.209 180.373 169.545 1.00 50.79  ? 31  ARG L CZ  1 
ATOM   223  N NH1 . ARG A 1 31  ? 236.835 180.891 170.593 1.00 50.79  ? 31  ARG L NH1 1 
ATOM   224  N NH2 . ARG A 1 31  ? 235.153 180.991 169.036 1.00 50.79  ? 31  ARG L NH2 1 
ATOM   225  N N   . ASN A 1 32  ? 239.375 175.522 164.259 1.00 37.72  ? 32  ASN L N   1 
ATOM   226  C CA  . ASN A 1 32  ? 238.912 174.986 162.992 1.00 37.72  ? 32  ASN L CA  1 
ATOM   227  C C   . ASN A 1 32  ? 239.519 173.602 162.824 1.00 37.72  ? 32  ASN L C   1 
ATOM   228  O O   . ASN A 1 32  ? 240.648 173.461 162.350 1.00 37.72  ? 32  ASN L O   1 
ATOM   229  C CB  . ASN A 1 32  ? 239.294 175.927 161.858 1.00 37.72  ? 32  ASN L CB  1 
ATOM   230  C CG  . ASN A 1 32  ? 238.631 177.286 161.987 1.00 37.72  ? 32  ASN L CG  1 
ATOM   231  O OD1 . ASN A 1 32  ? 239.017 178.246 161.320 1.00 37.72  ? 32  ASN L OD1 1 
ATOM   232  N ND2 . ASN A 1 32  ? 237.619 177.369 162.835 1.00 37.72  ? 32  ASN L ND2 1 
ATOM   233  N N   . LEU A 1 33  ? 238.770 172.583 163.228 1.00 36.97  ? 33  LEU L N   1 
ATOM   234  C CA  . LEU A 1 33  ? 239.216 171.209 163.075 1.00 36.97  ? 33  LEU L CA  1 
ATOM   235  C C   . LEU A 1 33  ? 237.992 170.308 163.102 1.00 36.97  ? 33  LEU L C   1 
ATOM   236  O O   . LEU A 1 33  ? 236.984 170.638 163.729 1.00 36.97  ? 33  LEU L O   1 
ATOM   237  C CB  . LEU A 1 33  ? 240.203 170.829 164.175 1.00 36.97  ? 33  LEU L CB  1 
ATOM   238  C CG  . LEU A 1 33  ? 240.780 169.431 164.053 1.00 36.97  ? 33  LEU L CG  1 
ATOM   239  C CD1 . LEU A 1 33  ? 241.560 169.355 162.775 1.00 36.97  ? 33  LEU L CD1 1 
ATOM   240  C CD2 . LEU A 1 33  ? 241.669 169.129 165.212 1.00 36.97  ? 33  LEU L CD2 1 
ATOM   241  N N   . ALA A 1 34  ? 238.081 169.177 162.410 1.00 33.70  ? 34  ALA L N   1 
ATOM   242  C CA  . ALA A 1 34  ? 236.976 168.239 162.318 1.00 33.70  ? 34  ALA L CA  1 
ATOM   243  C C   . ALA A 1 34  ? 237.481 166.820 162.521 1.00 33.70  ? 34  ALA L C   1 
ATOM   244  O O   . ALA A 1 34  ? 238.651 166.527 162.278 1.00 33.70  ? 34  ALA L O   1 
ATOM   245  C CB  . ALA A 1 34  ? 236.266 168.347 160.972 1.00 33.70  ? 34  ALA L CB  1 
ATOM   246  N N   . TRP A 1 35  ? 236.591 165.940 162.971 1.00 35.69  ? 35  TRP L N   1 
ATOM   247  C CA  . TRP A 1 35  ? 236.918 164.544 163.229 1.00 35.69  ? 35  TRP L CA  1 
ATOM   248  C C   . TRP A 1 35  ? 235.975 163.648 162.442 1.00 35.69  ? 35  TRP L C   1 
ATOM   249  O O   . TRP A 1 35  ? 234.755 163.802 162.533 1.00 35.69  ? 35  TRP L O   1 
ATOM   250  C CB  . TRP A 1 35  ? 236.814 164.224 164.721 1.00 35.69  ? 35  TRP L CB  1 
ATOM   251  C CG  . TRP A 1 35  ? 237.834 164.907 165.570 1.00 35.69  ? 35  TRP L CG  1 
ATOM   252  C CD1 . TRP A 1 35  ? 237.705 166.102 166.201 1.00 35.69  ? 35  TRP L CD1 1 
ATOM   253  C CD2 . TRP A 1 35  ? 239.140 164.424 165.890 1.00 35.69  ? 35  TRP L CD2 1 
ATOM   254  N NE1 . TRP A 1 35  ? 238.853 166.401 166.887 1.00 35.69  ? 35  TRP L NE1 1 
ATOM   255  C CE2 . TRP A 1 35  ? 239.748 165.381 166.713 1.00 35.69  ? 35  TRP L CE2 1 
ATOM   256  C CE3 . TRP A 1 35  ? 239.855 163.274 165.557 1.00 35.69  ? 35  TRP L CE3 1 
ATOM   257  C CZ2 . TRP A 1 35  ? 241.031 165.226 167.202 1.00 35.69  ? 35  TRP L CZ2 1 
ATOM   258  C CZ3 . TRP A 1 35  ? 241.125 163.124 166.043 1.00 35.69  ? 35  TRP L CZ3 1 
ATOM   259  C CH2 . TRP A 1 35  ? 241.701 164.090 166.857 1.00 35.69  ? 35  TRP L CH2 1 
ATOM   260  N N   . TYR A 1 36  ? 236.530 162.701 161.691 1.00 34.90  ? 36  TYR L N   1 
ATOM   261  C CA  . TYR A 1 36  ? 235.738 161.812 160.852 1.00 34.90  ? 36  TYR L CA  1 
ATOM   262  C C   . TYR A 1 36  ? 235.983 160.359 161.231 1.00 34.90  ? 36  TYR L C   1 
ATOM   263  O O   . TYR A 1 36  ? 237.108 159.973 161.556 1.00 34.90  ? 36  TYR L O   1 
ATOM   264  C CB  . TYR A 1 36  ? 236.060 162.010 159.373 1.00 34.90  ? 36  TYR L CB  1 
ATOM   265  C CG  . TYR A 1 36  ? 235.842 163.418 158.901 1.00 34.90  ? 36  TYR L CG  1 
ATOM   266  C CD1 . TYR A 1 36  ? 234.611 164.018 159.020 1.00 34.90  ? 36  TYR L CD1 1 
ATOM   267  C CD2 . TYR A 1 36  ? 236.867 164.146 158.339 1.00 34.90  ? 36  TYR L CD2 1 
ATOM   268  C CE1 . TYR A 1 36  ? 234.408 165.297 158.597 1.00 34.90  ? 36  TYR L CE1 1 
ATOM   269  C CE2 . TYR A 1 36  ? 236.671 165.426 157.920 1.00 34.90  ? 36  TYR L CE2 1 
ATOM   270  C CZ  . TYR A 1 36  ? 235.440 165.996 158.051 1.00 34.90  ? 36  TYR L CZ  1 
ATOM   271  O OH  . TYR A 1 36  ? 235.237 167.281 157.632 1.00 34.90  ? 36  TYR L OH  1 
ATOM   272  N N   . GLN A 1 37  ? 234.925 159.558 161.176 1.00 43.90  ? 37  GLN L N   1 
ATOM   273  C CA  . GLN A 1 37  ? 234.990 158.126 161.429 1.00 43.90  ? 37  GLN L CA  1 
ATOM   274  C C   . GLN A 1 37  ? 234.641 157.386 160.151 1.00 43.90  ? 37  GLN L C   1 
ATOM   275  O O   . GLN A 1 37  ? 233.575 157.612 159.576 1.00 43.90  ? 37  GLN L O   1 
ATOM   276  C CB  . GLN A 1 37  ? 234.026 157.726 162.543 1.00 43.90  ? 37  GLN L CB  1 
ATOM   277  C CG  . GLN A 1 37  ? 233.912 156.233 162.749 1.00 43.90  ? 37  GLN L CG  1 
ATOM   278  C CD  . GLN A 1 37  ? 232.843 155.870 163.750 1.00 43.90  ? 37  GLN L CD  1 
ATOM   279  O OE1 . GLN A 1 37  ? 231.653 156.048 163.497 1.00 43.90  ? 37  GLN L OE1 1 
ATOM   280  N NE2 . GLN A 1 37  ? 233.260 155.364 164.899 1.00 43.90  ? 37  GLN L NE2 1 
ATOM   281  N N   . GLN A 1 38  ? 235.527 156.495 159.715 1.00 49.18  ? 38  GLN L N   1 
ATOM   282  C CA  . GLN A 1 38  ? 235.415 155.872 158.398 1.00 49.18  ? 38  GLN L CA  1 
ATOM   283  C C   . GLN A 1 38  ? 235.456 154.361 158.585 1.00 49.18  ? 38  GLN L C   1 
ATOM   284  O O   . GLN A 1 38  ? 236.521 153.749 158.496 1.00 49.18  ? 38  GLN L O   1 
ATOM   285  C CB  . GLN A 1 38  ? 236.530 156.377 157.483 1.00 49.18  ? 38  GLN L CB  1 
ATOM   286  C CG  . GLN A 1 38  ? 236.374 156.068 156.003 1.00 49.18  ? 38  GLN L CG  1 
ATOM   287  C CD  . GLN A 1 38  ? 237.023 154.780 155.586 1.00 49.18  ? 38  GLN L CD  1 
ATOM   288  O OE1 . GLN A 1 38  ? 238.008 154.350 156.176 1.00 49.18  ? 38  GLN L OE1 1 
ATOM   289  N NE2 . GLN A 1 38  ? 236.496 154.169 154.538 1.00 49.18  ? 38  GLN L NE2 1 
ATOM   290  N N   . ARG A 1 39  ? 234.295 153.769 158.848 1.00 61.24  ? 39  ARG L N   1 
ATOM   291  C CA  . ARG A 1 39  ? 234.220 152.326 159.017 1.00 61.24  ? 39  ARG L CA  1 
ATOM   292  C C   . ARG A 1 39  ? 234.624 151.634 157.719 1.00 61.24  ? 39  ARG L C   1 
ATOM   293  O O   . ARG A 1 39  ? 234.209 152.061 156.640 1.00 61.24  ? 39  ARG L O   1 
ATOM   294  C CB  . ARG A 1 39  ? 232.809 151.902 159.410 1.00 61.24  ? 39  ARG L CB  1 
ATOM   295  C CG  . ARG A 1 39  ? 232.655 150.406 159.572 1.00 61.24  ? 39  ARG L CG  1 
ATOM   296  C CD  . ARG A 1 39  ? 231.292 150.023 160.107 1.00 61.24  ? 39  ARG L CD  1 
ATOM   297  N NE  . ARG A 1 39  ? 231.249 148.619 160.508 1.00 61.24  ? 39  ARG L NE  1 
ATOM   298  C CZ  . ARG A 1 39  ? 230.174 148.014 161.002 1.00 61.24  ? 39  ARG L CZ  1 
ATOM   299  N NH1 . ARG A 1 39  ? 230.231 146.735 161.341 1.00 61.24  ? 39  ARG L NH1 1 
ATOM   300  N NH2 . ARG A 1 39  ? 229.043 148.688 161.160 1.00 61.24  ? 39  ARG L NH2 1 
ATOM   301  N N   . PRO A 1 40  ? 235.428 150.576 157.789 1.00 60.47  ? 40  PRO L N   1 
ATOM   302  C CA  . PRO A 1 40  ? 235.928 149.945 156.561 1.00 60.47  ? 40  PRO L CA  1 
ATOM   303  C C   . PRO A 1 40  ? 234.801 149.512 155.634 1.00 60.47  ? 40  PRO L C   1 
ATOM   304  O O   . PRO A 1 40  ? 233.873 148.806 156.035 1.00 60.47  ? 40  PRO L O   1 
ATOM   305  C CB  . PRO A 1 40  ? 236.726 148.743 157.082 1.00 60.47  ? 40  PRO L CB  1 
ATOM   306  C CG  . PRO A 1 40  ? 236.339 148.595 158.523 1.00 60.47  ? 40  PRO L CG  1 
ATOM   307  C CD  . PRO A 1 40  ? 236.008 149.964 158.991 1.00 60.47  ? 40  PRO L CD  1 
ATOM   308  N N   . GLY A 1 41  ? 234.892 149.945 154.376 1.00 55.82  ? 41  GLY L N   1 
ATOM   309  C CA  . GLY A 1 41  ? 233.880 149.676 153.382 1.00 55.82  ? 41  GLY L CA  1 
ATOM   310  C C   . GLY A 1 41  ? 232.796 150.725 153.261 1.00 55.82  ? 41  GLY L C   1 
ATOM   311  O O   . GLY A 1 41  ? 232.019 150.678 152.301 1.00 55.82  ? 41  GLY L O   1 
ATOM   312  N N   . GLN A 1 42  ? 232.713 151.664 154.196 1.00 53.17  ? 42  GLN L N   1 
ATOM   313  C CA  . GLN A 1 42  ? 231.695 152.704 154.197 1.00 53.17  ? 42  GLN L CA  1 
ATOM   314  C C   . GLN A 1 42  ? 232.295 154.042 153.789 1.00 53.17  ? 42  GLN L C   1 
ATOM   315  O O   . GLN A 1 42  ? 233.512 154.205 153.684 1.00 53.17  ? 42  GLN L O   1 
ATOM   316  C CB  . GLN A 1 42  ? 231.050 152.840 155.582 1.00 53.17  ? 42  GLN L CB  1 
ATOM   317  C CG  . GLN A 1 42  ? 230.610 151.553 156.270 1.00 53.17  ? 42  GLN L CG  1 
ATOM   318  C CD  . GLN A 1 42  ? 229.838 150.617 155.367 1.00 53.17  ? 42  GLN L CD  1 
ATOM   319  O OE1 . GLN A 1 42  ? 230.410 149.886 154.564 1.00 53.17  ? 42  GLN L OE1 1 
ATOM   320  N NE2 . GLN A 1 42  ? 228.518 150.639 155.497 1.00 53.17  ? 42  GLN L NE2 1 
ATOM   321  N N   . ALA A 1 43  ? 231.415 155.003 153.560 1.00 41.39  ? 43  ALA L N   1 
ATOM   322  C CA  . ALA A 1 43  ? 231.831 156.384 153.407 1.00 41.39  ? 43  ALA L CA  1 
ATOM   323  C C   . ALA A 1 43  ? 232.049 157.008 154.780 1.00 41.39  ? 43  ALA L C   1 
ATOM   324  O O   . ALA A 1 43  ? 231.424 156.596 155.757 1.00 41.39  ? 43  ALA L O   1 
ATOM   325  C CB  . ALA A 1 43  ? 230.779 157.176 152.644 1.00 41.39  ? 43  ALA L CB  1 
ATOM   326  N N   . PRO A 1 44  ? 232.924 157.998 154.883 1.00 33.48  ? 44  PRO L N   1 
ATOM   327  C CA  . PRO A 1 44  ? 233.178 158.622 156.186 1.00 33.48  ? 44  PRO L CA  1 
ATOM   328  C C   . PRO A 1 44  ? 231.957 159.298 156.782 1.00 33.48  ? 44  PRO L C   1 
ATOM   329  O O   . PRO A 1 44  ? 230.884 159.320 156.174 1.00 33.48  ? 44  PRO L O   1 
ATOM   330  C CB  . PRO A 1 44  ? 234.276 159.639 155.870 1.00 33.48  ? 44  PRO L CB  1 
ATOM   331  C CG  . PRO A 1 44  ? 234.960 159.083 154.709 1.00 33.48  ? 44  PRO L CG  1 
ATOM   332  C CD  . PRO A 1 44  ? 233.913 158.413 153.883 1.00 33.48  ? 44  PRO L CD  1 
ATOM   333  N N   . ARG A 1 45  ? 232.108 159.844 157.983 1.00 40.88  ? 45  ARG L N   1 
ATOM   334  C CA  . ARG A 1 45  ? 231.003 160.477 158.683 1.00 40.88  ? 45  ARG L CA  1 
ATOM   335  C C   . ARG A 1 45  ? 231.563 161.552 159.599 1.00 40.88  ? 45  ARG L C   1 
ATOM   336  O O   . ARG A 1 45  ? 232.623 161.368 160.200 1.00 40.88  ? 45  ARG L O   1 
ATOM   337  C CB  . ARG A 1 45  ? 230.206 159.449 159.487 1.00 40.88  ? 45  ARG L CB  1 
ATOM   338  C CG  . ARG A 1 45  ? 228.774 159.842 159.777 1.00 40.88  ? 45  ARG L CG  1 
ATOM   339  C CD  . ARG A 1 45  ? 228.039 158.712 160.480 1.00 40.88  ? 45  ARG L CD  1 
ATOM   340  N NE  . ARG A 1 45  ? 228.899 158.028 161.438 1.00 40.88  ? 45  ARG L NE  1 
ATOM   341  C CZ  . ARG A 1 45  ? 228.862 158.232 162.749 1.00 40.88  ? 45  ARG L CZ  1 
ATOM   342  N NH1 . ARG A 1 45  ? 229.683 157.567 163.547 1.00 40.88  ? 45  ARG L NH1 1 
ATOM   343  N NH2 . ARG A 1 45  ? 228.002 159.099 163.261 1.00 40.88  ? 45  ARG L NH2 1 
ATOM   344  N N   . LEU A 1 46  ? 230.855 162.670 159.701 1.00 35.26  ? 46  LEU L N   1 
ATOM   345  C CA  . LEU A 1 46  ? 231.324 163.787 160.507 1.00 35.26  ? 46  LEU L CA  1 
ATOM   346  C C   . LEU A 1 46  ? 230.895 163.611 161.956 1.00 35.26  ? 46  LEU L C   1 
ATOM   347  O O   . LEU A 1 46  ? 229.726 163.334 162.234 1.00 35.26  ? 46  LEU L O   1 
ATOM   348  C CB  . LEU A 1 46  ? 230.781 165.100 159.952 1.00 35.26  ? 46  LEU L CB  1 
ATOM   349  C CG  . LEU A 1 46  ? 230.847 166.336 160.843 1.00 35.26  ? 46  LEU L CG  1 
ATOM   350  C CD1 . LEU A 1 46  ? 232.266 166.770 161.060 1.00 35.26  ? 46  LEU L CD1 1 
ATOM   351  C CD2 . LEU A 1 46  ? 230.045 167.456 160.230 1.00 35.26  ? 46  LEU L CD2 1 
ATOM   352  N N   . LEU A 1 47  ? 231.840 163.783 162.882 1.00 40.50  ? 47  LEU L N   1 
ATOM   353  C CA  . LEU A 1 47  ? 231.562 163.699 164.310 1.00 40.50  ? 47  LEU L CA  1 
ATOM   354  C C   . LEU A 1 47  ? 231.646 165.057 164.992 1.00 40.50  ? 47  LEU L C   1 
ATOM   355  O O   . LEU A 1 47  ? 230.676 165.507 165.607 1.00 40.50  ? 47  LEU L O   1 
ATOM   356  C CB  . LEU A 1 47  ? 232.533 162.726 164.985 1.00 40.50  ? 47  LEU L CB  1 
ATOM   357  C CG  . LEU A 1 47  ? 232.470 161.260 164.590 1.00 40.50  ? 47  LEU L CG  1 
ATOM   358  C CD1 . LEU A 1 47  ? 233.437 160.464 165.437 1.00 40.50  ? 47  LEU L CD1 1 
ATOM   359  C CD2 . LEU A 1 47  ? 231.064 160.743 164.747 1.00 40.50  ? 47  LEU L CD2 1 
ATOM   360  N N   . ILE A 1 48  ? 232.790 165.729 164.896 1.00 38.51  ? 48  ILE L N   1 
ATOM   361  C CA  . ILE A 1 48  ? 233.041 166.985 165.589 1.00 38.51  ? 48  ILE L CA  1 
ATOM   362  C C   . ILE A 1 48  ? 233.446 168.028 164.562 1.00 38.51  ? 48  ILE L C   1 
ATOM   363  O O   . ILE A 1 48  ? 234.298 167.762 163.709 1.00 38.51  ? 48  ILE L O   1 
ATOM   364  C CB  . ILE A 1 48  ? 234.141 166.832 166.654 1.00 38.51  ? 48  ILE L CB  1 
ATOM   365  C CG1 . ILE A 1 48  ? 233.889 165.599 167.511 1.00 38.51  ? 48  ILE L CG1 1 
ATOM   366  C CG2 . ILE A 1 48  ? 234.210 168.065 167.521 1.00 38.51  ? 48  ILE L CG2 1 
ATOM   367  C CD1 . ILE A 1 48  ? 232.634 165.680 168.316 1.00 38.51  ? 48  ILE L CD1 1 
ATOM   368  N N   . TYR A 1 49  ? 232.832 169.204 164.632 1.00 40.47  ? 49  TYR L N   1 
ATOM   369  C CA  . TYR A 1 49  ? 233.291 170.360 163.880 1.00 40.47  ? 49  TYR L CA  1 
ATOM   370  C C   . TYR A 1 49  ? 233.345 171.559 164.808 1.00 40.47  ? 49  TYR L C   1 
ATOM   371  O O   . TYR A 1 49  ? 232.486 171.719 165.676 1.00 40.47  ? 49  TYR L O   1 
ATOM   372  C CB  . TYR A 1 49  ? 232.404 170.664 162.680 1.00 40.47  ? 49  TYR L CB  1 
ATOM   373  C CG  . TYR A 1 49  ? 230.954 170.916 162.984 1.00 40.47  ? 49  TYR L CG  1 
ATOM   374  C CD1 . TYR A 1 49  ? 230.509 172.171 163.343 1.00 40.47  ? 49  TYR L CD1 1 
ATOM   375  C CD2 . TYR A 1 49  ? 230.024 169.907 162.860 1.00 40.47  ? 49  TYR L CD2 1 
ATOM   376  C CE1 . TYR A 1 49  ? 229.183 172.403 163.600 1.00 40.47  ? 49  TYR L CE1 1 
ATOM   377  C CE2 . TYR A 1 49  ? 228.695 170.130 163.113 1.00 40.47  ? 49  TYR L CE2 1 
ATOM   378  C CZ  . TYR A 1 49  ? 228.279 171.379 163.485 1.00 40.47  ? 49  TYR L CZ  1 
ATOM   379  O OH  . TYR A 1 49  ? 226.948 171.602 163.738 1.00 40.47  ? 49  TYR L OH  1 
ATOM   380  N N   . GLY A 1 50  ? 234.350 172.404 164.612 1.00 41.87  ? 50  GLY L N   1 
ATOM   381  C CA  . GLY A 1 50  ? 234.640 173.439 165.578 1.00 41.87  ? 50  GLY L CA  1 
ATOM   382  C C   . GLY A 1 50  ? 235.480 172.971 166.738 1.00 41.87  ? 50  GLY L C   1 
ATOM   383  O O   . GLY A 1 50  ? 235.669 173.732 167.691 1.00 41.87  ? 50  GLY L O   1 
ATOM   384  N N   . ALA A 1 51  ? 235.951 171.723 166.694 1.00 45.03  ? 51  ALA L N   1 
ATOM   385  C CA  . ALA A 1 51  ? 236.833 171.102 167.677 1.00 45.03  ? 51  ALA L CA  1 
ATOM   386  C C   . ALA A 1 51  ? 236.120 170.762 168.978 1.00 45.03  ? 51  ALA L C   1 
ATOM   387  O O   . ALA A 1 51  ? 236.697 170.096 169.840 1.00 45.03  ? 51  ALA L O   1 
ATOM   388  C CB  . ALA A 1 51  ? 238.043 171.991 167.965 1.00 45.03  ? 51  ALA L CB  1 
ATOM   389  N N   . SER A 1 52  ? 234.873 171.198 169.142 1.00 45.84  ? 52  SER L N   1 
ATOM   390  C CA  . SER A 1 52  ? 234.123 170.831 170.339 1.00 45.84  ? 52  SER L CA  1 
ATOM   391  C C   . SER A 1 52  ? 232.659 170.497 170.104 1.00 45.84  ? 52  SER L C   1 
ATOM   392  O O   . SER A 1 52  ? 232.079 169.788 170.931 1.00 45.84  ? 52  SER L O   1 
ATOM   393  C CB  . SER A 1 52  ? 234.209 171.946 171.386 1.00 45.84  ? 52  SER L CB  1 
ATOM   394  O OG  . SER A 1 52  ? 233.501 173.097 170.969 1.00 45.84  ? 52  SER L OG  1 
ATOM   395  N N   . THR A 1 53  ? 232.031 170.968 169.032 1.00 45.20  ? 53  THR L N   1 
ATOM   396  C CA  . THR A 1 53  ? 230.609 170.746 168.813 1.00 45.20  ? 53  THR L CA  1 
ATOM   397  C C   . THR A 1 53  ? 230.393 169.400 168.142 1.00 45.20  ? 53  THR L C   1 
ATOM   398  O O   . THR A 1 53  ? 231.150 169.021 167.246 1.00 45.20  ? 53  THR L O   1 
ATOM   399  C CB  . THR A 1 53  ? 230.015 171.855 167.950 1.00 45.20  ? 53  THR L CB  1 
ATOM   400  O OG1 . THR A 1 53  ? 230.370 173.128 168.497 1.00 45.20  ? 53  THR L OG1 1 
ATOM   401  C CG2 . THR A 1 53  ? 228.510 171.735 167.905 1.00 45.20  ? 53  THR L CG2 1 
ATOM   402  N N   . ARG A 1 54  ? 229.365 168.680 168.577 1.00 56.86  ? 54  ARG L N   1 
ATOM   403  C CA  . ARG A 1 54  ? 229.054 167.398 167.970 1.00 56.86  ? 54  ARG L CA  1 
ATOM   404  C C   . ARG A 1 54  ? 228.141 167.588 166.767 1.00 56.86  ? 54  ARG L C   1 
ATOM   405  O O   . ARG A 1 54  ? 227.437 168.591 166.638 1.00 56.86  ? 54  ARG L O   1 
ATOM   406  C CB  . ARG A 1 54  ? 228.394 166.467 168.984 1.00 56.86  ? 54  ARG L CB  1 
ATOM   407  C CG  . ARG A 1 54  ? 229.380 165.688 169.833 1.00 56.86  ? 54  ARG L CG  1 
ATOM   408  C CD  . ARG A 1 54  ? 228.700 164.590 170.626 1.00 56.86  ? 54  ARG L CD  1 
ATOM   409  N NE  . ARG A 1 54  ? 228.246 165.056 171.931 1.00 56.86  ? 54  ARG L NE  1 
ATOM   410  C CZ  . ARG A 1 54  ? 227.041 165.561 172.167 1.00 56.86  ? 54  ARG L CZ  1 
ATOM   411  N NH1 . ARG A 1 54  ? 226.155 165.665 171.186 1.00 56.86  ? 54  ARG L NH1 1 
ATOM   412  N NH2 . ARG A 1 54  ? 226.718 165.958 173.389 1.00 56.86  ? 54  ARG L NH2 1 
ATOM   413  N N   . ALA A 1 55  ? 228.149 166.597 165.884 1.00 55.23  ? 55  ALA L N   1 
ATOM   414  C CA  . ALA A 1 55  ? 227.306 166.625 164.699 1.00 55.23  ? 55  ALA L CA  1 
ATOM   415  C C   . ALA A 1 55  ? 225.867 166.313 165.102 1.00 55.23  ? 55  ALA L C   1 
ATOM   416  O O   . ALA A 1 55  ? 225.518 166.294 166.285 1.00 55.23  ? 55  ALA L O   1 
ATOM   417  C CB  . ALA A 1 55  ? 227.832 165.651 163.651 1.00 55.23  ? 55  ALA L CB  1 
ATOM   418  N N   . THR A 1 56  ? 225.002 166.072 164.119 1.00 63.91  ? 56  THR L N   1 
ATOM   419  C CA  . THR A 1 56  ? 223.602 165.804 164.426 1.00 63.91  ? 56  THR L CA  1 
ATOM   420  C C   . THR A 1 56  ? 223.418 164.416 165.030 1.00 63.91  ? 56  THR L C   1 
ATOM   421  O O   . THR A 1 56  ? 223.020 164.278 166.190 1.00 63.91  ? 56  THR L O   1 
ATOM   422  C CB  . THR A 1 56  ? 222.753 165.950 163.163 1.00 63.91  ? 56  THR L CB  1 
ATOM   423  O OG1 . THR A 1 56  ? 223.185 164.996 162.187 1.00 63.91  ? 56  THR L OG1 1 
ATOM   424  C CG2 . THR A 1 56  ? 222.900 167.346 162.589 1.00 63.91  ? 56  THR L CG2 1 
ATOM   425  N N   . GLY A 1 57  ? 223.714 163.376 164.258 1.00 65.68  ? 57  GLY L N   1 
ATOM   426  C CA  . GLY A 1 57  ? 223.512 162.017 164.718 1.00 65.68  ? 57  GLY L CA  1 
ATOM   427  C C   . GLY A 1 57  ? 224.724 161.410 165.392 1.00 65.68  ? 57  GLY L C   1 
ATOM   428  O O   . GLY A 1 57  ? 225.365 160.517 164.832 1.00 65.68  ? 57  GLY L O   1 
ATOM   429  N N   . VAL A 1 58  ? 225.058 161.889 166.587 1.00 66.78  ? 58  VAL L N   1 
ATOM   430  C CA  . VAL A 1 58  ? 226.198 161.384 167.341 1.00 66.78  ? 58  VAL L CA  1 
ATOM   431  C C   . VAL A 1 58  ? 225.779 161.195 168.791 1.00 66.78  ? 58  VAL L C   1 
ATOM   432  O O   . VAL A 1 58  ? 225.078 162.038 169.359 1.00 66.78  ? 58  VAL L O   1 
ATOM   433  C CB  . VAL A 1 58  ? 227.410 162.331 167.240 1.00 66.78  ? 58  VAL L CB  1 
ATOM   434  C CG1 . VAL A 1 58  ? 228.527 161.862 168.144 1.00 66.78  ? 58  VAL L CG1 1 
ATOM   435  C CG2 . VAL A 1 58  ? 227.896 162.412 165.810 1.00 66.78  ? 58  VAL L CG2 1 
ATOM   436  N N   . ALA A 1 59  ? 226.198 160.082 169.387 1.00 72.24  ? 59  ALA L N   1 
ATOM   437  C CA  . ALA A 1 59  ? 225.944 159.845 170.798 1.00 72.24  ? 59  ALA L CA  1 
ATOM   438  C C   . ALA A 1 59  ? 226.899 160.667 171.656 1.00 72.24  ? 59  ALA L C   1 
ATOM   439  O O   . ALA A 1 59  ? 227.955 161.112 171.205 1.00 72.24  ? 59  ALA L O   1 
ATOM   440  C CB  . ALA A 1 59  ? 226.086 158.361 171.132 1.00 72.24  ? 59  ALA L CB  1 
ATOM   441  N N   . ALA A 1 60  ? 226.518 160.853 172.919 1.00 73.63  ? 60  ALA L N   1 
ATOM   442  C CA  . ALA A 1 60  ? 227.287 161.705 173.816 1.00 73.63  ? 60  ALA L CA  1 
ATOM   443  C C   . ALA A 1 60  ? 228.643 161.121 174.184 1.00 73.63  ? 60  ALA L C   1 
ATOM   444  O O   . ALA A 1 60  ? 229.465 161.835 174.767 1.00 73.63  ? 60  ALA L O   1 
ATOM   445  C CB  . ALA A 1 60  ? 226.488 161.982 175.089 1.00 73.63  ? 60  ALA L CB  1 
ATOM   446  N N   . ARG A 1 61  ? 228.899 159.857 173.861 1.00 77.26  ? 61  ARG L N   1 
ATOM   447  C CA  . ARG A 1 61  ? 230.155 159.208 174.213 1.00 77.26  ? 61  ARG L CA  1 
ATOM   448  C C   . ARG A 1 61  ? 231.330 159.667 173.362 1.00 77.26  ? 61  ARG L C   1 
ATOM   449  O O   . ARG A 1 61  ? 232.431 159.128 173.519 1.00 77.26  ? 61  ARG L O   1 
ATOM   450  C CB  . ARG A 1 61  ? 229.997 157.694 174.100 1.00 77.26  ? 61  ARG L CB  1 
ATOM   451  C CG  . ARG A 1 61  ? 229.466 157.256 172.760 1.00 77.26  ? 61  ARG L CG  1 
ATOM   452  C CD  . ARG A 1 61  ? 228.499 156.103 172.909 1.00 77.26  ? 61  ARG L CD  1 
ATOM   453  N NE  . ARG A 1 61  ? 228.265 155.434 171.636 1.00 77.26  ? 61  ARG L NE  1 
ATOM   454  C CZ  . ARG A 1 61  ? 229.148 154.646 171.038 1.00 77.26  ? 61  ARG L CZ  1 
ATOM   455  N NH1 . ARG A 1 61  ? 230.325 154.418 171.601 1.00 77.26  ? 61  ARG L NH1 1 
ATOM   456  N NH2 . ARG A 1 61  ? 228.855 154.078 169.878 1.00 77.26  ? 61  ARG L NH2 1 
ATOM   457  N N   . PHE A 1 62  ? 231.128 160.628 172.466 1.00 66.33  ? 62  PHE L N   1 
ATOM   458  C CA  . PHE A 1 62  ? 232.201 161.227 171.684 1.00 66.33  ? 62  PHE L CA  1 
ATOM   459  C C   . PHE A 1 62  ? 232.397 162.658 172.162 1.00 66.33  ? 62  PHE L C   1 
ATOM   460  O O   . PHE A 1 62  ? 231.457 163.459 172.130 1.00 66.33  ? 62  PHE L O   1 
ATOM   461  C CB  . PHE A 1 62  ? 231.877 161.213 170.191 1.00 66.33  ? 62  PHE L CB  1 
ATOM   462  C CG  . PHE A 1 62  ? 231.986 159.863 169.556 1.00 66.33  ? 62  PHE L CG  1 
ATOM   463  C CD1 . PHE A 1 62  ? 233.187 159.185 169.539 1.00 66.33  ? 62  PHE L CD1 1 
ATOM   464  C CD2 . PHE A 1 62  ? 230.887 159.280 168.954 1.00 66.33  ? 62  PHE L CD2 1 
ATOM   465  C CE1 . PHE A 1 62  ? 233.285 157.948 168.947 1.00 66.33  ? 62  PHE L CE1 1 
ATOM   466  C CE2 . PHE A 1 62  ? 230.982 158.044 168.361 1.00 66.33  ? 62  PHE L CE2 1 
ATOM   467  C CZ  . PHE A 1 62  ? 232.183 157.378 168.358 1.00 66.33  ? 62  PHE L CZ  1 
ATOM   468  N N   . THR A 1 63  ? 233.610 162.978 172.601 1.00 61.74  ? 63  THR L N   1 
ATOM   469  C CA  . THR A 1 63  ? 233.930 164.327 173.040 1.00 61.74  ? 63  THR L CA  1 
ATOM   470  C C   . THR A 1 63  ? 235.310 164.716 172.535 1.00 61.74  ? 63  THR L C   1 
ATOM   471  O O   . THR A 1 63  ? 236.229 163.895 172.508 1.00 61.74  ? 63  THR L O   1 
ATOM   472  C CB  . THR A 1 63  ? 233.858 164.453 174.568 1.00 61.74  ? 63  THR L CB  1 
ATOM   473  O OG1 . THR A 1 63  ? 234.014 165.826 174.945 1.00 61.74  ? 63  THR L OG1 1 
ATOM   474  C CG2 . THR A 1 63  ? 234.929 163.613 175.243 1.00 61.74  ? 63  THR L CG2 1 
ATOM   475  N N   . GLY A 1 64  ? 235.444 165.967 172.122 1.00 52.16  ? 64  GLY L N   1 
ATOM   476  C CA  . GLY A 1 64  ? 236.708 166.471 171.631 1.00 52.16  ? 64  GLY L CA  1 
ATOM   477  C C   . GLY A 1 64  ? 237.008 167.830 172.224 1.00 52.16  ? 64  GLY L C   1 
ATOM   478  O O   . GLY A 1 64  ? 236.108 168.583 172.593 1.00 52.16  ? 64  GLY L O   1 
ATOM   479  N N   . SER A 1 65  ? 238.298 168.135 172.314 1.00 57.00  ? 65  SER L N   1 
ATOM   480  C CA  . SER A 1 65  ? 238.729 169.385 172.917 1.00 57.00  ? 65  SER L CA  1 
ATOM   481  C C   . SER A 1 65  ? 240.086 169.772 172.356 1.00 57.00  ? 65  SER L C   1 
ATOM   482  O O   . SER A 1 65  ? 240.796 168.953 171.768 1.00 57.00  ? 65  SER L O   1 
ATOM   483  C CB  . SER A 1 65  ? 238.791 169.280 174.443 1.00 57.00  ? 65  SER L CB  1 
ATOM   484  O OG  . SER A 1 65  ? 237.525 168.950 174.981 1.00 57.00  ? 65  SER L OG  1 
ATOM   485  N N   . GLY A 1 66  ? 240.435 171.031 172.545 1.00 59.83  ? 66  GLY L N   1 
ATOM   486  C CA  . GLY A 1 66  ? 241.712 171.542 172.090 1.00 59.83  ? 66  GLY L CA  1 
ATOM   487  C C   . GLY A 1 66  ? 241.585 172.975 171.627 1.00 59.83  ? 66  GLY L C   1 
ATOM   488  O O   . GLY A 1 66  ? 240.493 173.509 171.453 1.00 59.83  ? 66  GLY L O   1 
ATOM   489  N N   . PHE A 1 67  ? 242.744 173.598 171.425 1.00 55.45  ? 67  PHE L N   1 
ATOM   490  C CA  . PHE A 1 67  ? 242.822 174.982 170.985 1.00 55.45  ? 67  PHE L CA  1 
ATOM   491  C C   . PHE A 1 67  ? 244.257 175.285 170.598 1.00 55.45  ? 67  PHE L C   1 
ATOM   492  O O   . PHE A 1 67  ? 245.187 174.881 171.295 1.00 55.45  ? 67  PHE L O   1 
ATOM   493  C CB  . PHE A 1 67  ? 242.356 175.940 172.086 1.00 55.45  ? 67  PHE L CB  1 
ATOM   494  C CG  . PHE A 1 67  ? 241.846 177.253 171.575 1.00 55.45  ? 67  PHE L CG  1 
ATOM   495  C CD1 . PHE A 1 67  ? 242.716 178.196 171.057 1.00 55.45  ? 67  PHE L CD1 1 
ATOM   496  C CD2 . PHE A 1 67  ? 240.496 177.549 171.621 1.00 55.45  ? 67  PHE L CD2 1 
ATOM   497  C CE1 . PHE A 1 67  ? 242.248 179.408 170.593 1.00 55.45  ? 67  PHE L CE1 1 
ATOM   498  C CE2 . PHE A 1 67  ? 240.023 178.758 171.156 1.00 55.45  ? 67  PHE L CE2 1 
ATOM   499  C CZ  . PHE A 1 67  ? 240.901 179.688 170.640 1.00 55.45  ? 67  PHE L CZ  1 
ATOM   500  N N   . GLY A 1 68  ? 244.428 175.988 169.488 1.00 55.33  ? 68  GLY L N   1 
ATOM   501  C CA  . GLY A 1 68  ? 245.740 176.428 169.064 1.00 55.33  ? 68  GLY L CA  1 
ATOM   502  C C   . GLY A 1 68  ? 246.541 175.400 168.295 1.00 55.33  ? 68  GLY L C   1 
ATOM   503  O O   . GLY A 1 68  ? 246.664 175.497 167.073 1.00 55.33  ? 68  GLY L O   1 
ATOM   504  N N   . THR A 1 69  ? 247.111 174.420 168.990 1.00 62.47  ? 69  THR L N   1 
ATOM   505  C CA  . THR A 1 69  ? 247.937 173.421 168.319 1.00 62.47  ? 69  THR L CA  1 
ATOM   506  C C   . THR A 1 69  ? 247.714 171.992 168.784 1.00 62.47  ? 69  THR L C   1 
ATOM   507  O O   . THR A 1 69  ? 248.074 171.070 168.046 1.00 62.47  ? 69  THR L O   1 
ATOM   508  C CB  . THR A 1 69  ? 249.422 173.762 168.480 1.00 62.47  ? 69  THR L CB  1 
ATOM   509  O OG1 . THR A 1 69  ? 250.212 172.806 167.766 1.00 62.47  ? 69  THR L OG1 1 
ATOM   510  C CG2 . THR A 1 69  ? 249.817 173.733 169.939 1.00 62.47  ? 69  THR L CG2 1 
ATOM   511  N N   . GLU A 1 70  ? 247.150 171.756 169.964 1.00 63.55  ? 70  GLU L N   1 
ATOM   512  C CA  . GLU A 1 70  ? 246.959 170.413 170.493 1.00 63.55  ? 70  GLU L CA  1 
ATOM   513  C C   . GLU A 1 70  ? 245.468 170.126 170.570 1.00 63.55  ? 70  GLU L C   1 
ATOM   514  O O   . GLU A 1 70  ? 244.732 170.847 171.249 1.00 63.55  ? 70  GLU L O   1 
ATOM   515  C CB  . GLU A 1 70  ? 247.601 170.285 171.872 1.00 63.55  ? 70  GLU L CB  1 
ATOM   516  C CG  . GLU A 1 70  ? 247.505 168.909 172.503 1.00 63.55  ? 70  GLU L CG  1 
ATOM   517  C CD  . GLU A 1 70  ? 248.279 167.859 171.735 1.00 63.55  ? 70  GLU L CD  1 
ATOM   518  O OE1 . GLU A 1 70  ? 249.248 168.228 171.041 1.00 63.55  ? 70  GLU L OE1 1 
ATOM   519  O OE2 . GLU A 1 70  ? 247.933 166.663 171.836 1.00 63.55  ? 70  GLU L OE2 1 
ATOM   520  N N   . PHE A 1 71  ? 245.028 169.071 169.893 1.00 55.87  ? 71  PHE L N   1 
ATOM   521  C CA  . PHE A 1 71  ? 243.628 168.675 169.883 1.00 55.87  ? 71  PHE L CA  1 
ATOM   522  C C   . PHE A 1 71  ? 243.514 167.213 170.282 1.00 55.87  ? 71  PHE L C   1 
ATOM   523  O O   . PHE A 1 71  ? 244.370 166.400 169.923 1.00 55.87  ? 71  PHE L O   1 
ATOM   524  C CB  . PHE A 1 71  ? 242.997 168.868 168.507 1.00 55.87  ? 71  PHE L CB  1 
ATOM   525  C CG  . PHE A 1 71  ? 243.034 170.281 167.998 1.00 55.87  ? 71  PHE L CG  1 
ATOM   526  C CD1 . PHE A 1 71  ? 244.104 170.739 167.256 1.00 55.87  ? 71  PHE L CD1 1 
ATOM   527  C CD2 . PHE A 1 71  ? 241.974 171.136 168.219 1.00 55.87  ? 71  PHE L CD2 1 
ATOM   528  C CE1 . PHE A 1 71  ? 244.125 172.027 166.770 1.00 55.87  ? 71  PHE L CE1 1 
ATOM   529  C CE2 . PHE A 1 71  ? 241.994 172.422 167.736 1.00 55.87  ? 71  PHE L CE2 1 
ATOM   530  C CZ  . PHE A 1 71  ? 243.070 172.866 167.011 1.00 55.87  ? 71  PHE L CZ  1 
ATOM   531  N N   . THR A 1 72  ? 242.456 166.875 171.022 1.00 56.12  ? 72  THR L N   1 
ATOM   532  C CA  . THR A 1 72  ? 242.249 165.508 171.479 1.00 56.12  ? 72  THR L CA  1 
ATOM   533  C C   . THR A 1 72  ? 240.795 165.096 171.296 1.00 56.12  ? 72  THR L C   1 
ATOM   534  O O   . THR A 1 72  ? 239.888 165.930 171.309 1.00 56.12  ? 72  THR L O   1 
ATOM   535  C CB  . THR A 1 72  ? 242.632 165.326 172.953 1.00 56.12  ? 72  THR L CB  1 
ATOM   536  O OG1 . THR A 1 72  ? 241.812 166.168 173.769 1.00 56.12  ? 72  THR L OG1 1 
ATOM   537  C CG2 . THR A 1 72  ? 244.093 165.671 173.182 1.00 56.12  ? 72  THR L CG2 1 
ATOM   538  N N   . LEU A 1 73  ? 240.591 163.790 171.131 1.00 52.91  ? 73  LEU L N   1 
ATOM   539  C CA  . LEU A 1 73  ? 239.275 163.172 171.060 1.00 52.91  ? 73  LEU L CA  1 
ATOM   540  C C   . LEU A 1 73  ? 239.239 161.997 172.022 1.00 52.91  ? 73  LEU L C   1 
ATOM   541  O O   . LEU A 1 73  ? 240.176 161.197 172.061 1.00 52.91  ? 73  LEU L O   1 
ATOM   542  C CB  . LEU A 1 73  ? 238.957 162.680 169.647 1.00 52.91  ? 73  LEU L CB  1 
ATOM   543  C CG  . LEU A 1 73  ? 237.740 161.771 169.464 1.00 52.91  ? 73  LEU L CG  1 
ATOM   544  C CD1 . LEU A 1 73  ? 236.466 162.526 169.719 1.00 52.91  ? 73  LEU L CD1 1 
ATOM   545  C CD2 . LEU A 1 73  ? 237.724 161.181 168.075 1.00 52.91  ? 73  LEU L CD2 1 
ATOM   546  N N   . THR A 1 74  ? 238.156 161.889 172.788 1.00 61.95  ? 74  THR L N   1 
ATOM   547  C CA  . THR A 1 74  ? 238.018 160.864 173.814 1.00 61.95  ? 74  THR L CA  1 
ATOM   548  C C   . THR A 1 74  ? 236.778 160.026 173.549 1.00 61.95  ? 74  THR L C   1 
ATOM   549  O O   . THR A 1 74  ? 235.680 160.568 173.390 1.00 61.95  ? 74  THR L O   1 
ATOM   550  C CB  . THR A 1 74  ? 237.934 161.488 175.204 1.00 61.95  ? 74  THR L CB  1 
ATOM   551  O OG1 . THR A 1 74  ? 239.127 162.235 175.466 1.00 61.95  ? 74  THR L OG1 1 
ATOM   552  C CG2 . THR A 1 74  ? 237.775 160.414 176.256 1.00 61.95  ? 74  THR L CG2 1 
ATOM   553  N N   . ILE A 1 75  ? 236.955 158.709 173.516 1.00 72.60  ? 75  ILE L N   1 
ATOM   554  C CA  . ILE A 1 75  ? 235.865 157.765 173.301 1.00 72.60  ? 75  ILE L CA  1 
ATOM   555  C C   . ILE A 1 75  ? 235.742 156.914 174.554 1.00 72.60  ? 75  ILE L C   1 
ATOM   556  O O   . ILE A 1 75  ? 236.695 156.222 174.931 1.00 72.60  ? 75  ILE L O   1 
ATOM   557  C CB  . ILE A 1 75  ? 236.111 156.875 172.077 1.00 72.60  ? 75  ILE L CB  1 
ATOM   558  C CG1 . ILE A 1 75  ? 236.179 157.709 170.806 1.00 72.60  ? 75  ILE L CG1 1 
ATOM   559  C CG2 . ILE A 1 75  ? 234.994 155.871 171.943 1.00 72.60  ? 75  ILE L CG2 1 
ATOM   560  C CD1 . ILE A 1 75  ? 236.672 156.933 169.618 1.00 72.60  ? 75  ILE L CD1 1 
ATOM   561  N N   . SER A 1 76  ? 234.570 156.944 175.184 1.00 82.13  ? 76  SER L N   1 
ATOM   562  C CA  . SER A 1 76  ? 234.327 156.230 176.430 1.00 82.13  ? 76  SER L CA  1 
ATOM   563  C C   . SER A 1 76  ? 233.252 155.176 176.214 1.00 82.13  ? 76  SER L C   1 
ATOM   564  O O   . SER A 1 76  ? 232.170 155.483 175.704 1.00 82.13  ? 76  SER L O   1 
ATOM   565  C CB  . SER A 1 76  ? 233.906 157.195 177.540 1.00 82.13  ? 76  SER L CB  1 
ATOM   566  O OG  . SER A 1 76  ? 234.079 156.608 178.816 1.00 82.13  ? 76  SER L OG  1 
ATOM   567  N N   . GLY A 1 77  ? 233.544 153.941 176.615 1.00 82.07  ? 77  GLY L N   1 
ATOM   568  C CA  . GLY A 1 77  ? 232.591 152.861 176.458 1.00 82.07  ? 77  GLY L CA  1 
ATOM   569  C C   . GLY A 1 77  ? 232.410 152.422 175.021 1.00 82.07  ? 77  GLY L C   1 
ATOM   570  O O   . GLY A 1 77  ? 231.353 152.643 174.425 1.00 82.07  ? 77  GLY L O   1 
ATOM   571  N N   . LEU A 1 78  ? 233.442 151.805 174.453 1.00 77.91  ? 78  LEU L N   1 
ATOM   572  C CA  . LEU A 1 78  ? 233.400 151.381 173.061 1.00 77.91  ? 78  LEU L CA  1 
ATOM   573  C C   . LEU A 1 78  ? 232.385 150.264 172.852 1.00 77.91  ? 78  LEU L C   1 
ATOM   574  O O   . LEU A 1 78  ? 232.231 149.374 173.692 1.00 77.91  ? 78  LEU L O   1 
ATOM   575  C CB  . LEU A 1 78  ? 234.781 150.908 172.614 1.00 77.91  ? 78  LEU L CB  1 
ATOM   576  C CG  . LEU A 1 78  ? 235.805 151.976 172.242 1.00 77.91  ? 78  LEU L CG  1 
ATOM   577  C CD1 . LEU A 1 78  ? 237.193 151.395 172.263 1.00 77.91  ? 78  LEU L CD1 1 
ATOM   578  C CD2 . LEU A 1 78  ? 235.499 152.524 170.876 1.00 77.91  ? 78  LEU L CD2 1 
ATOM   579  N N   . GLN A 1 79  ? 231.689 150.320 171.724 1.00 81.21  ? 79  GLN L N   1 
ATOM   580  C CA  . GLN A 1 79  ? 230.854 149.231 171.249 1.00 81.21  ? 79  GLN L CA  1 
ATOM   581  C C   . GLN A 1 79  ? 231.580 148.497 170.126 1.00 81.21  ? 79  GLN L C   1 
ATOM   582  O O   . GLN A 1 79  ? 232.757 148.742 169.854 1.00 81.21  ? 79  GLN L O   1 
ATOM   583  C CB  . GLN A 1 79  ? 229.491 149.759 170.797 1.00 81.21  ? 79  GLN L CB  1 
ATOM   584  C CG  . GLN A 1 79  ? 228.493 149.960 171.923 1.00 81.21  ? 79  GLN L CG  1 
ATOM   585  C CD  . GLN A 1 79  ? 228.795 151.182 172.759 1.00 81.21  ? 79  GLN L CD  1 
ATOM   586  O OE1 . GLN A 1 79  ? 229.633 152.003 172.393 1.00 81.21  ? 79  GLN L OE1 1 
ATOM   587  N NE2 . GLN A 1 79  ? 228.107 151.314 173.887 1.00 81.21  ? 79  GLN L NE2 1 
ATOM   588  N N   . SER A 1 80  ? 230.878 147.576 169.465 1.00 87.67  ? 80  SER L N   1 
ATOM   589  C CA  . SER A 1 80  ? 231.485 146.846 168.357 1.00 87.67  ? 80  SER L CA  1 
ATOM   590  C C   . SER A 1 80  ? 231.583 147.712 167.108 1.00 87.67  ? 80  SER L C   1 
ATOM   591  O O   . SER A 1 80  ? 232.490 147.528 166.288 1.00 87.67  ? 80  SER L O   1 
ATOM   592  C CB  . SER A 1 80  ? 230.686 145.577 168.067 1.00 87.67  ? 80  SER L CB  1 
ATOM   593  O OG  . SER A 1 80  ? 229.309 145.870 167.905 1.00 87.67  ? 80  SER L OG  1 
ATOM   594  N N   . GLU A 1 81  ? 230.655 148.656 166.943 1.00 81.78  ? 81  GLU L N   1 
ATOM   595  C CA  . GLU A 1 81  ? 230.629 149.501 165.754 1.00 81.78  ? 81  GLU L CA  1 
ATOM   596  C C   . GLU A 1 81  ? 231.792 150.481 165.706 1.00 81.78  ? 81  GLU L C   1 
ATOM   597  O O   . GLU A 1 81  ? 232.161 150.931 164.617 1.00 81.78  ? 81  GLU L O   1 
ATOM   598  C CB  . GLU A 1 81  ? 229.300 150.259 165.697 1.00 81.78  ? 81  GLU L CB  1 
ATOM   599  C CG  . GLU A 1 81  ? 228.773 150.571 164.297 1.00 81.78  ? 81  GLU L CG  1 
ATOM   600  C CD  . GLU A 1 81  ? 229.527 151.696 163.612 1.00 81.78  ? 81  GLU L CD  1 
ATOM   601  O OE1 . GLU A 1 81  ? 229.953 151.519 162.453 1.00 81.78  ? 81  GLU L OE1 1 
ATOM   602  O OE2 . GLU A 1 81  ? 229.691 152.765 164.234 1.00 81.78  ? 81  GLU L OE2 1 
ATOM   603  N N   . ASP A 1 82  ? 232.397 150.798 166.849 1.00 76.78  ? 82  ASP L N   1 
ATOM   604  C CA  . ASP A 1 82  ? 233.321 151.919 166.954 1.00 76.78  ? 82  ASP L CA  1 
ATOM   605  C C   . ASP A 1 82  ? 234.775 151.521 166.753 1.00 76.78  ? 82  ASP L C   1 
ATOM   606  O O   . ASP A 1 82  ? 235.668 152.149 167.333 1.00 76.78  ? 82  ASP L O   1 
ATOM   607  C CB  . ASP A 1 82  ? 233.143 152.606 168.304 1.00 76.78  ? 82  ASP L CB  1 
ATOM   608  C CG  . ASP A 1 82  ? 231.819 153.316 168.415 1.00 76.78  ? 82  ASP L CG  1 
ATOM   609  O OD1 . ASP A 1 82  ? 231.293 153.761 167.376 1.00 76.78  ? 82  ASP L OD1 1 
ATOM   610  O OD2 . ASP A 1 82  ? 231.300 153.422 169.541 1.00 76.78  ? 82  ASP L OD2 1 
ATOM   611  N N   . PHE A 1 83  ? 235.042 150.496 165.956 1.00 75.16  ? 83  PHE L N   1 
ATOM   612  C CA  . PHE A 1 83  ? 236.402 150.138 165.567 1.00 75.16  ? 83  PHE L CA  1 
ATOM   613  C C   . PHE A 1 83  ? 236.556 150.480 164.088 1.00 75.16  ? 83  PHE L C   1 
ATOM   614  O O   . PHE A 1 83  ? 236.098 149.736 163.217 1.00 75.16  ? 83  PHE L O   1 
ATOM   615  C CB  . PHE A 1 83  ? 236.686 148.669 165.851 1.00 75.16  ? 83  PHE L CB  1 
ATOM   616  C CG  . PHE A 1 83  ? 236.580 148.306 167.305 1.00 75.16  ? 83  PHE L CG  1 
ATOM   617  C CD1 . PHE A 1 83  ? 237.617 148.582 168.177 1.00 75.16  ? 83  PHE L CD1 1 
ATOM   618  C CD2 . PHE A 1 83  ? 235.448 147.687 167.799 1.00 75.16  ? 83  PHE L CD2 1 
ATOM   619  C CE1 . PHE A 1 83  ? 237.522 148.252 169.513 1.00 75.16  ? 83  PHE L CE1 1 
ATOM   620  C CE2 . PHE A 1 83  ? 235.354 147.354 169.133 1.00 75.16  ? 83  PHE L CE2 1 
ATOM   621  C CZ  . PHE A 1 83  ? 236.391 147.640 169.990 1.00 75.16  ? 83  PHE L CZ  1 
ATOM   622  N N   . ALA A 1 84  ? 237.202 151.606 163.815 1.00 61.33  ? 84  ALA L N   1 
ATOM   623  C CA  . ALA A 1 84  ? 237.331 152.152 162.471 1.00 61.33  ? 84  ALA L CA  1 
ATOM   624  C C   . ALA A 1 84  ? 238.658 152.898 162.402 1.00 61.33  ? 84  ALA L C   1 
ATOM   625  O O   . ALA A 1 84  ? 239.572 152.627 163.186 1.00 61.33  ? 84  ALA L O   1 
ATOM   626  C CB  . ALA A 1 84  ? 236.122 153.038 162.137 1.00 61.33  ? 84  ALA L CB  1 
ATOM   627  N N   . VAL A 1 85  ? 238.786 153.810 161.443 1.00 56.02  ? 85  VAL L N   1 
ATOM   628  C CA  . VAL A 1 85  ? 239.921 154.722 161.375 1.00 56.02  ? 85  VAL L CA  1 
ATOM   629  C C   . VAL A 1 85  ? 239.408 156.146 161.542 1.00 56.02  ? 85  VAL L C   1 
ATOM   630  O O   . VAL A 1 85  ? 238.285 156.459 161.132 1.00 56.02  ? 85  VAL L O   1 
ATOM   631  C CB  . VAL A 1 85  ? 240.698 154.561 160.057 1.00 56.02  ? 85  VAL L CB  1 
ATOM   632  C CG1 . VAL A 1 85  ? 241.259 153.167 159.963 1.00 56.02  ? 85  VAL L CG1 1 
ATOM   633  C CG2 . VAL A 1 85  ? 239.793 154.827 158.888 1.00 56.02  ? 85  VAL L CG2 1 
ATOM   634  N N   . TYR A 1 86  ? 240.221 157.006 162.152 1.00 49.96  ? 86  TYR L N   1 
ATOM   635  C CA  . TYR A 1 86  ? 239.796 158.348 162.532 1.00 49.96  ? 86  TYR L CA  1 
ATOM   636  C C   . TYR A 1 86  ? 240.730 159.398 161.946 1.00 49.96  ? 86  TYR L C   1 
ATOM   637  O O   . TYR A 1 86  ? 241.953 159.276 162.061 1.00 49.96  ? 86  TYR L O   1 
ATOM   638  C CB  . TYR A 1 86  ? 239.744 158.478 164.051 1.00 49.96  ? 86  TYR L CB  1 
ATOM   639  C CG  . TYR A 1 86  ? 238.614 157.705 164.677 1.00 49.96  ? 86  TYR L CG  1 
ATOM   640  C CD1 . TYR A 1 86  ? 238.748 156.361 164.971 1.00 49.96  ? 86  TYR L CD1 1 
ATOM   641  C CD2 . TYR A 1 86  ? 237.410 158.320 164.967 1.00 49.96  ? 86  TYR L CD2 1 
ATOM   642  C CE1 . TYR A 1 86  ? 237.720 155.655 165.540 1.00 49.96  ? 86  TYR L CE1 1 
ATOM   643  C CE2 . TYR A 1 86  ? 236.377 157.620 165.534 1.00 49.96  ? 86  TYR L CE2 1 
ATOM   644  C CZ  . TYR A 1 86  ? 236.537 156.289 165.815 1.00 49.96  ? 86  TYR L CZ  1 
ATOM   645  O OH  . TYR A 1 86  ? 235.505 155.589 166.382 1.00 49.96  ? 86  TYR L OH  1 
ATOM   646  N N   . TYR A 1 87  ? 240.149 160.440 161.346 1.00 39.59  ? 87  TYR L N   1 
ATOM   647  C CA  . TYR A 1 87  ? 240.890 161.501 160.676 1.00 39.59  ? 87  TYR L CA  1 
ATOM   648  C C   . TYR A 1 87  ? 240.574 162.856 161.295 1.00 39.59  ? 87  TYR L C   1 
ATOM   649  O O   . TYR A 1 87  ? 239.521 163.046 161.906 1.00 39.59  ? 87  TYR L O   1 
ATOM   650  C CB  . TYR A 1 87  ? 240.556 161.559 159.184 1.00 39.59  ? 87  TYR L CB  1 
ATOM   651  C CG  . TYR A 1 87  ? 240.876 160.307 158.420 1.00 39.59  ? 87  TYR L CG  1 
ATOM   652  C CD1 . TYR A 1 87  ? 242.170 160.018 158.049 1.00 39.59  ? 87  TYR L CD1 1 
ATOM   653  C CD2 . TYR A 1 87  ? 239.881 159.425 158.056 1.00 39.59  ? 87  TYR L CD2 1 
ATOM   654  C CE1 . TYR A 1 87  ? 242.467 158.882 157.350 1.00 39.59  ? 87  TYR L CE1 1 
ATOM   655  C CE2 . TYR A 1 87  ? 240.169 158.286 157.359 1.00 39.59  ? 87  TYR L CE2 1 
ATOM   656  C CZ  . TYR A 1 87  ? 241.465 158.018 157.008 1.00 39.59  ? 87  TYR L CZ  1 
ATOM   657  O OH  . TYR A 1 87  ? 241.761 156.877 156.310 1.00 39.59  ? 87  TYR L OH  1 
ATOM   658  N N   . CYS A 1 88  ? 241.496 163.801 161.121 1.00 39.73  ? 88  CYS L N   1 
ATOM   659  C CA  . CYS A 1 88  ? 241.289 165.196 161.486 1.00 39.73  ? 88  CYS L CA  1 
ATOM   660  C C   . CYS A 1 88  ? 241.792 166.076 160.355 1.00 39.73  ? 88  CYS L C   1 
ATOM   661  O O   . CYS A 1 88  ? 242.873 165.826 159.817 1.00 39.73  ? 88  CYS L O   1 
ATOM   662  C CB  . CYS A 1 88  ? 242.005 165.547 162.796 1.00 39.73  ? 88  CYS L CB  1 
ATOM   663  S SG  . CYS A 1 88  ? 243.737 165.027 162.929 1.00 39.73  ? 88  CYS L SG  1 
ATOM   664  N N   . GLN A 1 89  ? 241.018 167.100 159.986 1.00 33.09  ? 89  GLN L N   1 
ATOM   665  C CA  . GLN A 1 89  ? 241.408 167.992 158.900 1.00 33.09  ? 89  GLN L CA  1 
ATOM   666  C C   . GLN A 1 89  ? 241.159 169.439 159.290 1.00 33.09  ? 89  GLN L C   1 
ATOM   667  O O   . GLN A 1 89  ? 240.156 169.752 159.933 1.00 33.09  ? 89  GLN L O   1 
ATOM   668  C CB  . GLN A 1 89  ? 240.667 167.650 157.605 1.00 33.09  ? 89  GLN L CB  1 
ATOM   669  C CG  . GLN A 1 89  ? 239.195 168.000 157.541 1.00 33.09  ? 89  GLN L CG  1 
ATOM   670  C CD  . GLN A 1 89  ? 238.942 169.301 156.819 1.00 33.09  ? 89  GLN L CD  1 
ATOM   671  O OE1 . GLN A 1 89  ? 239.729 169.712 155.978 1.00 33.09  ? 89  GLN L OE1 1 
ATOM   672  N NE2 . GLN A 1 89  ? 237.824 169.933 157.113 1.00 33.09  ? 89  GLN L NE2 1 
ATOM   673  N N   . GLU A 1 90  ? 242.080 170.314 158.895 1.00 37.60  ? 90  GLU L N   1 
ATOM   674  C CA  . GLU A 1 90  ? 242.101 171.709 159.319 1.00 37.60  ? 90  GLU L CA  1 
ATOM   675  C C   . GLU A 1 90  ? 241.662 172.627 158.189 1.00 37.60  ? 90  GLU L C   1 
ATOM   676  O O   . GLU A 1 90  ? 242.005 172.394 157.028 1.00 37.60  ? 90  GLU L O   1 
ATOM   677  C CB  . GLU A 1 90  ? 243.500 172.097 159.792 1.00 37.60  ? 90  GLU L CB  1 
ATOM   678  C CG  . GLU A 1 90  ? 244.582 171.973 158.729 1.00 37.60  ? 90  GLU L CG  1 
ATOM   679  C CD  . GLU A 1 90  ? 244.702 173.198 157.848 1.00 37.60  ? 90  GLU L CD  1 
ATOM   680  O OE1 . GLU A 1 90  ? 244.232 174.276 158.251 1.00 37.60  ? 90  GLU L OE1 1 
ATOM   681  O OE2 . GLU A 1 90  ? 245.280 173.088 156.750 1.00 37.60  ? 90  GLU L OE2 1 
ATOM   682  N N   . TYR A 1 91  ? 240.908 173.669 158.524 1.00 32.78  ? 91  TYR L N   1 
ATOM   683  C CA  . TYR A 1 91  ? 240.371 174.569 157.513 1.00 32.78  ? 91  TYR L CA  1 
ATOM   684  C C   . TYR A 1 91  ? 240.404 176.020 157.969 1.00 32.78  ? 91  TYR L C   1 
ATOM   685  O O   . TYR A 1 91  ? 239.427 176.753 157.820 1.00 32.78  ? 91  TYR L O   1 
ATOM   686  C CB  . TYR A 1 91  ? 238.956 174.165 157.133 1.00 32.78  ? 91  TYR L CB  1 
ATOM   687  C CG  . TYR A 1 91  ? 238.004 173.974 158.284 1.00 32.78  ? 91  TYR L CG  1 
ATOM   688  C CD1 . TYR A 1 91  ? 237.898 172.759 158.923 1.00 32.78  ? 91  TYR L CD1 1 
ATOM   689  C CD2 . TYR A 1 91  ? 237.185 174.997 158.707 1.00 32.78  ? 91  TYR L CD2 1 
ATOM   690  C CE1 . TYR A 1 91  ? 237.021 172.575 159.962 1.00 32.78  ? 91  TYR L CE1 1 
ATOM   691  C CE2 . TYR A 1 91  ? 236.307 174.823 159.745 1.00 32.78  ? 91  TYR L CE2 1 
ATOM   692  C CZ  . TYR A 1 91  ? 236.228 173.611 160.368 1.00 32.78  ? 91  TYR L CZ  1 
ATOM   693  O OH  . TYR A 1 91  ? 235.348 173.438 161.404 1.00 32.78  ? 91  TYR L OH  1 
ATOM   694  N N   . ASN A 1 92  ? 241.522 176.480 158.522 1.00 33.14  ? 92  ASN L N   1 
ATOM   695  C CA  . ASN A 1 92  ? 241.631 177.874 158.949 1.00 33.14  ? 92  ASN L CA  1 
ATOM   696  C C   . ASN A 1 92  ? 242.291 178.721 157.862 1.00 33.14  ? 92  ASN L C   1 
ATOM   697  O O   . ASN A 1 92  ? 243.200 179.494 158.140 1.00 33.14  ? 92  ASN L O   1 
ATOM   698  C CB  . ASN A 1 92  ? 242.388 177.975 160.229 1.00 33.14  ? 92  ASN L CB  1 
ATOM   699  C CG  . ASN A 1 92  ? 242.231 179.327 160.879 1.00 33.14  ? 92  ASN L CG  1 
ATOM   700  O OD1 . ASN A 1 92  ? 243.212 180.020 161.144 1.00 33.14  ? 92  ASN L OD1 1 
ATOM   701  N ND2 . ASN A 1 92  ? 240.988 179.718 161.130 1.00 33.14  ? 92  ASN L ND2 1 
ATOM   702  N N   . ASN A 1 93  ? 241.802 178.580 156.625 1.00 31.09  ? 93  ASN L N   1 
ATOM   703  C CA  . ASN A 1 93  ? 242.055 179.410 155.439 1.00 31.09  ? 93  ASN L CA  1 
ATOM   704  C C   . ASN A 1 93  ? 241.269 178.912 154.237 1.00 31.09  ? 93  ASN L C   1 
ATOM   705  O O   . ASN A 1 93  ? 240.551 177.914 154.320 1.00 31.09  ? 93  ASN L O   1 
ATOM   706  C CB  . ASN A 1 93  ? 243.524 179.494 154.999 1.00 31.09  ? 93  ASN L CB  1 
ATOM   707  C CG  . ASN A 1 93  ? 244.397 180.289 155.921 1.00 31.09  ? 93  ASN L CG  1 
ATOM   708  O OD1 . ASN A 1 93  ? 245.306 179.760 156.554 1.00 31.09  ? 93  ASN L OD1 1 
ATOM   709  N ND2 . ASN A 1 93  ? 244.162 181.589 155.962 1.00 31.09  ? 93  ASN L ND2 1 
ATOM   710  N N   . TRP A 1 94  ? 241.425 179.601 153.111 1.00 29.03  ? 94  TRP L N   1 
ATOM   711  C CA  . TRP A 1 94  ? 240.827 179.295 151.815 1.00 29.03  ? 94  TRP L CA  1 
ATOM   712  C C   . TRP A 1 94  ? 241.497 178.128 151.083 1.00 29.03  ? 94  TRP L C   1 
ATOM   713  O O   . TRP A 1 94  ? 240.806 177.202 150.634 1.00 29.03  ? 94  TRP L O   1 
ATOM   714  C CB  . TRP A 1 94  ? 240.894 180.538 150.926 1.00 29.03  ? 94  TRP L CB  1 
ATOM   715  C CG  . TRP A 1 94  ? 240.290 181.772 151.510 1.00 29.03  ? 94  TRP L CG  1 
ATOM   716  C CD1 . TRP A 1 94  ? 240.934 182.937 151.778 1.00 29.03  ? 94  TRP L CD1 1 
ATOM   717  C CD2 . TRP A 1 94  ? 238.925 181.977 151.876 1.00 29.03  ? 94  TRP L CD2 1 
ATOM   718  N NE1 . TRP A 1 94  ? 240.061 183.854 152.300 1.00 29.03  ? 94  TRP L NE1 1 
ATOM   719  C CE2 . TRP A 1 94  ? 238.818 183.287 152.369 1.00 29.03  ? 94  TRP L CE2 1 
ATOM   720  C CE3 . TRP A 1 94  ? 237.783 181.179 151.837 1.00 29.03  ? 94  TRP L CE3 1 
ATOM   721  C CZ2 . TRP A 1 94  ? 237.622 183.816 152.822 1.00 29.03  ? 94  TRP L CZ2 1 
ATOM   722  C CZ3 . TRP A 1 94  ? 236.594 181.707 152.288 1.00 29.03  ? 94  TRP L CZ3 1 
ATOM   723  C CH2 . TRP A 1 94  ? 236.521 183.013 152.773 1.00 29.03  ? 94  TRP L CH2 1 
ATOM   724  N N   . PRO A 1 95  ? 242.822 178.137 150.926 1.00 35.73  ? 95  PRO L N   1 
ATOM   725  C CA  . PRO A 1 95  ? 243.479 177.236 149.970 1.00 35.73  ? 95  PRO L CA  1 
ATOM   726  C C   . PRO A 1 95  ? 243.555 175.820 150.516 1.00 35.73  ? 95  PRO L C   1 
ATOM   727  O O   . PRO A 1 95  ? 242.844 175.508 151.480 1.00 35.73  ? 95  PRO L O   1 
ATOM   728  C CB  . PRO A 1 95  ? 244.866 177.882 149.798 1.00 35.73  ? 95  PRO L CB  1 
ATOM   729  C CG  . PRO A 1 95  ? 245.092 178.714 150.976 1.00 35.73  ? 95  PRO L CG  1 
ATOM   730  C CD  . PRO A 1 95  ? 243.824 178.838 151.746 1.00 35.73  ? 95  PRO L CD  1 
ATOM   731  N N   . PRO A 1 96  ? 244.364 174.907 149.901 1.00 32.78  ? 96  PRO L N   1 
ATOM   732  C CA  . PRO A 1 96  ? 244.362 173.500 150.330 1.00 32.78  ? 96  PRO L CA  1 
ATOM   733  C C   . PRO A 1 96  ? 244.169 173.197 151.807 1.00 32.78  ? 96  PRO L C   1 
ATOM   734  O O   . PRO A 1 96  ? 244.811 173.789 152.677 1.00 32.78  ? 96  PRO L O   1 
ATOM   735  C CB  . PRO A 1 96  ? 245.747 173.029 149.882 1.00 32.78  ? 96  PRO L CB  1 
ATOM   736  C CG  . PRO A 1 96  ? 246.008 173.805 148.650 1.00 32.78  ? 96  PRO L CG  1 
ATOM   737  C CD  . PRO A 1 96  ? 245.155 175.038 148.663 1.00 32.78  ? 96  PRO L CD  1 
ATOM   738  N N   . TRP A 1 97  ? 243.273 172.252 152.076 1.00 27.07  ? 97  TRP L N   1 
ATOM   739  C CA  . TRP A 1 97  ? 243.014 171.750 153.414 1.00 27.07  ? 97  TRP L CA  1 
ATOM   740  C C   . TRP A 1 97  ? 243.554 170.335 153.547 1.00 27.07  ? 97  TRP L C   1 
ATOM   741  O O   . TRP A 1 97  ? 243.286 169.480 152.702 1.00 27.07  ? 97  TRP L O   1 
ATOM   742  C CB  . TRP A 1 97  ? 241.520 171.786 153.709 1.00 27.07  ? 97  TRP L CB  1 
ATOM   743  C CG  . TRP A 1 97  ? 241.011 173.161 153.744 1.00 27.07  ? 97  TRP L CG  1 
ATOM   744  C CD1 . TRP A 1 97  ? 241.650 174.235 154.254 1.00 27.07  ? 97  TRP L CD1 1 
ATOM   745  C CD2 . TRP A 1 97  ? 239.767 173.637 153.237 1.00 27.07  ? 97  TRP L CD2 1 
ATOM   746  N NE1 . TRP A 1 97  ? 240.881 175.356 154.112 1.00 27.07  ? 97  TRP L NE1 1 
ATOM   747  C CE2 . TRP A 1 97  ? 239.717 175.013 153.485 1.00 27.07  ? 97  TRP L CE2 1 
ATOM   748  C CE3 . TRP A 1 97  ? 238.690 173.033 152.600 1.00 27.07  ? 97  TRP L CE3 1 
ATOM   749  C CZ2 . TRP A 1 97  ? 238.642 175.793 153.120 1.00 27.07  ? 97  TRP L CZ2 1 
ATOM   750  C CZ3 . TRP A 1 97  ? 237.628 173.811 152.237 1.00 27.07  ? 97  TRP L CZ3 1 
ATOM   751  C CH2 . TRP A 1 97  ? 237.611 175.176 152.495 1.00 27.07  ? 97  TRP L CH2 1 
ATOM   752  N N   . THR A 1 98  ? 244.303 170.093 154.613 1.00 32.67  ? 98  THR L N   1 
ATOM   753  C CA  . THR A 1 98  ? 245.059 168.866 154.787 1.00 32.67  ? 98  THR L CA  1 
ATOM   754  C C   . THR A 1 98  ? 244.343 167.932 155.748 1.00 32.67  ? 98  THR L C   1 
ATOM   755  O O   . THR A 1 98  ? 243.906 168.350 156.823 1.00 32.67  ? 98  THR L O   1 
ATOM   756  C CB  . THR A 1 98  ? 246.454 169.167 155.322 1.00 32.67  ? 98  THR L CB  1 
ATOM   757  O OG1 . THR A 1 98  ? 246.340 170.050 156.441 1.00 32.67  ? 98  THR L OG1 1 
ATOM   758  C CG2 . THR A 1 98  ? 247.297 169.829 154.256 1.00 32.67  ? 98  THR L CG2 1 
ATOM   759  N N   . PHE A 1 99  ? 244.240 166.667 155.360 1.00 27.89  ? 99  PHE L N   1 
ATOM   760  C CA  . PHE A 1 99  ? 243.658 165.637 156.205 1.00 27.89  ? 99  PHE L CA  1 
ATOM   761  C C   . PHE A 1 99  ? 244.741 164.977 157.044 1.00 27.89  ? 99  PHE L C   1 
ATOM   762  O O   . PHE A 1 99  ? 245.850 164.733 156.564 1.00 27.89  ? 99  PHE L O   1 
ATOM   763  C CB  . PHE A 1 99  ? 242.959 164.581 155.351 1.00 27.89  ? 99  PHE L CB  1 
ATOM   764  C CG  . PHE A 1 99  ? 241.501 164.830 155.151 1.00 27.89  ? 99  PHE L CG  1 
ATOM   765  C CD1 . PHE A 1 99  ? 240.581 164.371 156.058 1.00 27.89  ? 99  PHE L CD1 1 
ATOM   766  C CD2 . PHE A 1 99  ? 241.053 165.514 154.050 1.00 27.89  ? 99  PHE L CD2 1 
ATOM   767  C CE1 . PHE A 1 99  ? 239.253 164.590 155.874 1.00 27.89  ? 99  PHE L CE1 1 
ATOM   768  C CE2 . PHE A 1 99  ? 239.722 165.733 153.867 1.00 27.89  ? 99  PHE L CE2 1 
ATOM   769  C CZ  . PHE A 1 99  ? 238.823 165.272 154.780 1.00 27.89  ? 99  PHE L CZ  1 
ATOM   770  N N   . GLY A 1 100 ? 244.417 164.683 158.296 1.00 39.41  ? 100 GLY L N   1 
ATOM   771  C CA  . GLY A 1 100 ? 245.333 163.932 159.124 1.00 39.41  ? 100 GLY L CA  1 
ATOM   772  C C   . GLY A 1 100 ? 245.572 162.540 158.575 1.00 39.41  ? 100 GLY L C   1 
ATOM   773  O O   . GLY A 1 100 ? 244.785 162.003 157.799 1.00 39.41  ? 100 GLY L O   1 
ATOM   774  N N   . GLN A 1 101 ? 246.687 161.941 158.982 1.00 46.22  ? 101 GLN L N   1 
ATOM   775  C CA  . GLN A 1 101 ? 247.084 160.665 158.402 1.00 46.22  ? 101 GLN L CA  1 
ATOM   776  C C   . GLN A 1 101 ? 246.236 159.494 158.874 1.00 46.22  ? 101 GLN L C   1 
ATOM   777  O O   . GLN A 1 101 ? 246.315 158.419 158.273 1.00 46.22  ? 101 GLN L O   1 
ATOM   778  C CB  . GLN A 1 101 ? 248.551 160.385 158.703 1.00 46.22  ? 101 GLN L CB  1 
ATOM   779  C CG  . GLN A 1 101 ? 249.476 161.389 158.073 1.00 46.22  ? 101 GLN L CG  1 
ATOM   780  C CD  . GLN A 1 101 ? 249.447 161.315 156.567 1.00 46.22  ? 101 GLN L CD  1 
ATOM   781  O OE1 . GLN A 1 101 ? 249.370 160.232 155.990 1.00 46.22  ? 101 GLN L OE1 1 
ATOM   782  N NE2 . GLN A 1 101 ? 249.511 162.470 155.917 1.00 46.22  ? 101 GLN L NE2 1 
ATOM   783  N N   . GLY A 1 102 ? 245.444 159.663 159.927 1.00 49.36  ? 102 GLY L N   1 
ATOM   784  C CA  . GLY A 1 102 ? 244.524 158.624 160.340 1.00 49.36  ? 102 GLY L CA  1 
ATOM   785  C C   . GLY A 1 102 ? 245.116 157.581 161.261 1.00 49.36  ? 102 GLY L C   1 
ATOM   786  O O   . GLY A 1 102 ? 246.216 157.081 161.014 1.00 49.36  ? 102 GLY L O   1 
ATOM   787  N N   . THR A 1 103 ? 244.392 157.241 162.324 1.00 61.26  ? 103 THR L N   1 
ATOM   788  C CA  . THR A 1 103 ? 244.795 156.192 163.249 1.00 61.26  ? 103 THR L CA  1 
ATOM   789  C C   . THR A 1 103 ? 243.654 155.200 163.420 1.00 61.26  ? 103 THR L C   1 
ATOM   790  O O   . THR A 1 103 ? 242.482 155.555 163.264 1.00 61.26  ? 103 THR L O   1 
ATOM   791  C CB  . THR A 1 103 ? 245.201 156.756 164.610 1.00 61.26  ? 103 THR L CB  1 
ATOM   792  O OG1 . THR A 1 103 ? 245.745 155.704 165.413 1.00 61.26  ? 103 THR L OG1 1 
ATOM   793  C CG2 . THR A 1 103 ? 244.006 157.348 165.322 1.00 61.26  ? 103 THR L CG2 1 
ATOM   794  N N   . LYS A 1 104 ? 244.007 153.957 163.727 1.00 66.17  ? 104 LYS L N   1 
ATOM   795  C CA  . LYS A 1 104 ? 243.064 152.848 163.767 1.00 66.17  ? 104 LYS L CA  1 
ATOM   796  C C   . LYS A 1 104 ? 242.951 152.330 165.192 1.00 66.17  ? 104 LYS L C   1 
ATOM   797  O O   . LYS A 1 104 ? 243.951 152.271 165.912 1.00 66.17  ? 104 LYS L O   1 
ATOM   798  C CB  . LYS A 1 104 ? 243.516 151.729 162.826 1.00 66.17  ? 104 LYS L CB  1 
ATOM   799  C CG  . LYS A 1 104 ? 242.574 150.543 162.744 1.00 66.17  ? 104 LYS L CG  1 
ATOM   800  C CD  . LYS A 1 104 ? 243.246 149.371 162.047 1.00 66.17  ? 104 LYS L CD  1 
ATOM   801  C CE  . LYS A 1 104 ? 242.235 148.337 161.580 1.00 66.17  ? 104 LYS L CE  1 
ATOM   802  N NZ  . LYS A 1 104 ? 241.003 148.346 162.407 1.00 66.17  ? 104 LYS L NZ  1 
ATOM   803  N N   . VAL A 1 105 ? 241.738 151.962 165.597 1.00 68.22  ? 105 VAL L N   1 
ATOM   804  C CA  . VAL A 1 105 ? 241.484 151.379 166.910 1.00 68.22  ? 105 VAL L CA  1 
ATOM   805  C C   . VAL A 1 105 ? 241.078 149.923 166.715 1.00 68.22  ? 105 VAL L C   1 
ATOM   806  O O   . VAL A 1 105 ? 240.118 149.626 165.995 1.00 68.22  ? 105 VAL L O   1 
ATOM   807  C CB  . VAL A 1 105 ? 240.418 152.167 167.686 1.00 68.22  ? 105 VAL L CB  1 
ATOM   808  C CG1 . VAL A 1 105 ? 240.946 153.528 168.038 1.00 68.22  ? 105 VAL L CG1 1 
ATOM   809  C CG2 . VAL A 1 105 ? 239.164 152.330 166.862 1.00 68.22  ? 105 VAL L CG2 1 
ATOM   810  N N   . GLU A 1 106 ? 241.817 149.016 167.341 1.00 80.55  ? 106 GLU L N   1 
ATOM   811  C CA  . GLU A 1 106 ? 241.616 147.583 167.190 1.00 80.55  ? 106 GLU L CA  1 
ATOM   812  C C   . GLU A 1 106 ? 240.919 147.025 168.426 1.00 80.55  ? 106 GLU L C   1 
ATOM   813  O O   . GLU A 1 106 ? 240.549 147.758 169.345 1.00 80.55  ? 106 GLU L O   1 
ATOM   814  C CB  . GLU A 1 106 ? 242.953 146.881 166.951 1.00 80.55  ? 106 GLU L CB  1 
ATOM   815  C CG  . GLU A 1 106 ? 243.849 147.585 165.952 1.00 80.55  ? 106 GLU L CG  1 
ATOM   816  C CD  . GLU A 1 106 ? 245.241 146.993 165.901 1.00 80.55  ? 106 GLU L CD  1 
ATOM   817  O OE1 . GLU A 1 106 ? 245.553 146.134 166.750 1.00 80.55  ? 106 GLU L OE1 1 
ATOM   818  O OE2 . GLU A 1 106 ? 246.024 147.382 165.010 1.00 80.55  ? 106 GLU L OE2 1 
ATOM   819  N N   . ILE A 1 107 ? 240.741 145.707 168.443 1.00 84.65  ? 107 ILE L N   1 
ATOM   820  C CA  . ILE A 1 107 ? 240.167 145.004 169.585 1.00 84.65  ? 107 ILE L CA  1 
ATOM   821  C C   . ILE A 1 107 ? 241.275 144.227 170.277 1.00 84.65  ? 107 ILE L C   1 
ATOM   822  O O   . ILE A 1 107 ? 242.023 143.485 169.628 1.00 84.65  ? 107 ILE L O   1 
ATOM   823  C CB  . ILE A 1 107 ? 239.027 144.068 169.156 1.00 84.65  ? 107 ILE L CB  1 
ATOM   824  C CG1 . ILE A 1 107 ? 237.850 144.875 168.620 1.00 84.65  ? 107 ILE L CG1 1 
ATOM   825  C CG2 . ILE A 1 107 ? 238.576 143.220 170.325 1.00 84.65  ? 107 ILE L CG2 1 
ATOM   826  C CD1 . ILE A 1 107 ? 236.682 144.024 168.182 1.00 84.65  ? 107 ILE L CD1 1 
ATOM   827  N N   . LYS A 1 108 ? 241.385 144.398 171.590 1.00 87.18  ? 108 LYS L N   1 
ATOM   828  C CA  . LYS A 1 108 ? 242.437 143.747 172.360 1.00 87.18  ? 108 LYS L CA  1 
ATOM   829  C C   . LYS A 1 108 ? 241.942 142.450 172.985 1.00 87.18  ? 108 LYS L C   1 
ATOM   830  O O   . LYS A 1 108 ? 240.807 142.036 172.759 1.00 87.18  ? 108 LYS L O   1 
ATOM   831  C CB  . LYS A 1 108 ? 242.959 144.688 173.444 1.00 87.18  ? 108 LYS L CB  1 
ATOM   832  C CG  . LYS A 1 108 ? 244.126 144.134 174.239 1.00 87.18  ? 108 LYS L CG  1 
ATOM   833  C CD  . LYS A 1 108 ? 244.386 144.971 175.478 1.00 87.18  ? 108 LYS L CD  1 
ATOM   834  C CE  . LYS A 1 108 ? 245.856 144.967 175.847 1.00 87.18  ? 108 LYS L CE  1 
ATOM   835  N NZ  . LYS A 1 108 ? 246.574 146.120 175.243 1.00 87.18  ? 108 LYS L NZ  1 
ATOM   836  N N   . VAL B 2 2   ? 218.851 165.659 152.114 1.00 63.42  ? 2   VAL H N   1 
ATOM   837  C CA  . VAL B 2 2   ? 219.813 164.921 152.918 1.00 63.42  ? 2   VAL H CA  1 
ATOM   838  C C   . VAL B 2 2   ? 220.232 163.643 152.208 1.00 63.42  ? 2   VAL H C   1 
ATOM   839  O O   . VAL B 2 2   ? 220.441 162.608 152.834 1.00 63.42  ? 2   VAL H O   1 
ATOM   840  C CB  . VAL B 2 2   ? 219.247 164.615 154.304 1.00 63.42  ? 2   VAL H CB  1 
ATOM   841  C CG1 . VAL B 2 2   ? 219.090 165.897 155.093 1.00 63.42  ? 2   VAL H CG1 1 
ATOM   842  C CG2 . VAL B 2 2   ? 217.907 163.911 154.177 1.00 63.42  ? 2   VAL H CG2 1 
ATOM   843  N N   . GLN B 2 3   ? 220.375 163.733 150.889 1.00 64.30  ? 3   GLN H N   1 
ATOM   844  C CA  . GLN B 2 3   ? 220.666 162.558 150.074 1.00 64.30  ? 3   GLN H CA  1 
ATOM   845  C C   . GLN B 2 3   ? 221.561 162.996 148.924 1.00 64.30  ? 3   GLN H C   1 
ATOM   846  O O   . GLN B 2 3   ? 221.117 163.739 148.044 1.00 64.30  ? 3   GLN H O   1 
ATOM   847  C CB  . GLN B 2 3   ? 219.374 161.928 149.563 1.00 64.30  ? 3   GLN H CB  1 
ATOM   848  C CG  . GLN B 2 3   ? 219.558 160.857 148.502 1.00 64.30  ? 3   GLN H CG  1 
ATOM   849  C CD  . GLN B 2 3   ? 219.819 159.490 149.094 1.00 64.30  ? 3   GLN H CD  1 
ATOM   850  O OE1 . GLN B 2 3   ? 219.715 159.294 150.303 1.00 64.30  ? 3   GLN H OE1 1 
ATOM   851  N NE2 . GLN B 2 3   ? 220.162 158.533 148.241 1.00 64.30  ? 3   GLN H NE2 1 
ATOM   852  N N   . LEU B 2 4   ? 222.809 162.538 148.932 1.00 54.63  ? 4   LEU H N   1 
ATOM   853  C CA  . LEU B 2 4   ? 223.770 162.830 147.875 1.00 54.63  ? 4   LEU H CA  1 
ATOM   854  C C   . LEU B 2 4   ? 224.023 161.536 147.115 1.00 54.63  ? 4   LEU H C   1 
ATOM   855  O O   . LEU B 2 4   ? 224.560 160.579 147.680 1.00 54.63  ? 4   LEU H O   1 
ATOM   856  C CB  . LEU B 2 4   ? 225.069 163.385 148.454 1.00 54.63  ? 4   LEU H CB  1 
ATOM   857  C CG  . LEU B 2 4   ? 225.213 164.884 148.722 1.00 54.63  ? 4   LEU H CG  1 
ATOM   858  C CD1 . LEU B 2 4   ? 225.254 165.665 147.432 1.00 54.63  ? 4   LEU H CD1 1 
ATOM   859  C CD2 . LEU B 2 4   ? 224.107 165.394 149.613 1.00 54.63  ? 4   LEU H CD2 1 
ATOM   860  N N   . VAL B 2 5   ? 223.638 161.499 145.844 1.00 54.74  ? 5   VAL H N   1 
ATOM   861  C CA  . VAL B 2 5   ? 223.808 160.321 145.000 1.00 54.74  ? 5   VAL H CA  1 
ATOM   862  C C   . VAL B 2 5   ? 224.705 160.688 143.826 1.00 54.74  ? 5   VAL H C   1 
ATOM   863  O O   . VAL B 2 5   ? 224.478 161.702 143.155 1.00 54.74  ? 5   VAL H O   1 
ATOM   864  C CB  . VAL B 2 5   ? 222.453 159.769 144.524 1.00 54.74  ? 5   VAL H CB  1 
ATOM   865  C CG1 . VAL B 2 5   ? 221.636 160.849 143.841 1.00 54.74  ? 5   VAL H CG1 1 
ATOM   866  C CG2 . VAL B 2 5   ? 222.663 158.594 143.591 1.00 54.74  ? 5   VAL H CG2 1 
ATOM   867  N N   . GLU B 2 6   ? 225.727 159.872 143.582 1.00 47.36  ? 6   GLU H N   1 
ATOM   868  C CA  . GLU B 2 6   ? 226.735 160.173 142.580 1.00 47.36  ? 6   GLU H CA  1 
ATOM   869  C C   . GLU B 2 6   ? 226.690 159.148 141.458 1.00 47.36  ? 6   GLU H C   1 
ATOM   870  O O   . GLU B 2 6   ? 226.234 158.017 141.637 1.00 47.36  ? 6   GLU H O   1 
ATOM   871  C CB  . GLU B 2 6   ? 228.133 160.186 143.185 1.00 47.36  ? 6   GLU H CB  1 
ATOM   872  C CG  . GLU B 2 6   ? 228.281 161.095 144.361 1.00 47.36  ? 6   GLU H CG  1 
ATOM   873  C CD  . GLU B 2 6   ? 229.293 160.577 145.331 1.00 47.36  ? 6   GLU H CD  1 
ATOM   874  O OE1 . GLU B 2 6   ? 230.160 159.795 144.897 1.00 47.36  ? 6   GLU H OE1 1 
ATOM   875  O OE2 . GLU B 2 6   ? 229.219 160.940 146.520 1.00 47.36  ? 6   GLU H OE2 1 
ATOM   876  N N   . SER B 2 7   ? 227.195 159.555 140.297 1.00 53.03  ? 7   SER H N   1 
ATOM   877  C CA  . SER B 2 7   ? 227.197 158.708 139.115 1.00 53.03  ? 7   SER H CA  1 
ATOM   878  C C   . SER B 2 7   ? 228.337 159.140 138.204 1.00 53.03  ? 7   SER H C   1 
ATOM   879  O O   . SER B 2 7   ? 229.074 160.082 138.502 1.00 53.03  ? 7   SER H O   1 
ATOM   880  C CB  . SER B 2 7   ? 225.852 158.777 138.390 1.00 53.03  ? 7   SER H CB  1 
ATOM   881  O OG  . SER B 2 7   ? 225.450 160.123 138.199 1.00 53.03  ? 7   SER H OG  1 
ATOM   882  N N   . GLY B 2 8   ? 228.478 158.439 137.083 1.00 50.79  ? 8   GLY H N   1 
ATOM   883  C CA  . GLY B 2 8   ? 229.466 158.780 136.088 1.00 50.79  ? 8   GLY H CA  1 
ATOM   884  C C   . GLY B 2 8   ? 230.817 158.125 136.264 1.00 50.79  ? 8   GLY H C   1 
ATOM   885  O O   . GLY B 2 8   ? 231.682 158.286 135.395 1.00 50.79  ? 8   GLY H O   1 
ATOM   886  N N   . GLY B 2 9   ? 231.035 157.396 137.352 1.00 53.19  ? 9   GLY H N   1 
ATOM   887  C CA  . GLY B 2 9   ? 232.299 156.714 137.526 1.00 53.19  ? 9   GLY H CA  1 
ATOM   888  C C   . GLY B 2 9   ? 232.425 155.519 136.603 1.00 53.19  ? 9   GLY H C   1 
ATOM   889  O O   . GLY B 2 9   ? 231.446 154.864 136.254 1.00 53.19  ? 9   GLY H O   1 
ATOM   890  N N   . GLY B 2 10  ? 233.659 155.227 136.207 1.00 52.02  ? 10  GLY H N   1 
ATOM   891  C CA  . GLY B 2 10  ? 233.894 154.116 135.310 1.00 52.02  ? 10  GLY H CA  1 
ATOM   892  C C   . GLY B 2 10  ? 235.356 153.795 135.102 1.00 52.02  ? 10  GLY H C   1 
ATOM   893  O O   . GLY B 2 10  ? 236.171 153.965 136.011 1.00 52.02  ? 10  GLY H O   1 
ATOM   894  N N   . LEU B 2 11  ? 235.696 153.317 133.909 1.00 53.01  ? 11  LEU H N   1 
ATOM   895  C CA  . LEU B 2 11  ? 237.067 153.001 133.536 1.00 53.01  ? 11  LEU H CA  1 
ATOM   896  C C   . LEU B 2 11  ? 237.491 153.950 132.428 1.00 53.01  ? 11  LEU H C   1 
ATOM   897  O O   . LEU B 2 11  ? 236.746 154.150 131.464 1.00 53.01  ? 11  LEU H O   1 
ATOM   898  C CB  . LEU B 2 11  ? 237.183 151.560 133.042 1.00 53.01  ? 11  LEU H CB  1 
ATOM   899  C CG  . LEU B 2 11  ? 236.340 150.513 133.766 1.00 53.01  ? 11  LEU H CG  1 
ATOM   900  C CD1 . LEU B 2 11  ? 236.462 149.173 133.062 1.00 53.01  ? 11  LEU H CD1 1 
ATOM   901  C CD2 . LEU B 2 11  ? 236.717 150.396 135.224 1.00 53.01  ? 11  LEU H CD2 1 
ATOM   902  N N   . VAL B 2 12  ? 238.674 154.539 132.559 1.00 61.58  ? 12  VAL H N   1 
ATOM   903  C CA  . VAL B 2 12  ? 239.198 155.409 131.517 1.00 61.58  ? 12  VAL H CA  1 
ATOM   904  C C   . VAL B 2 12  ? 240.624 154.994 131.203 1.00 61.58  ? 12  VAL H C   1 
ATOM   905  O O   . VAL B 2 12  ? 241.329 154.429 132.044 1.00 61.58  ? 12  VAL H O   1 
ATOM   906  C CB  . VAL B 2 12  ? 239.148 156.899 131.911 1.00 61.58  ? 12  VAL H CB  1 
ATOM   907  C CG1 . VAL B 2 12  ? 237.766 157.277 132.407 1.00 61.58  ? 12  VAL H CG1 1 
ATOM   908  C CG2 . VAL B 2 12  ? 240.194 157.206 132.952 1.00 61.58  ? 12  VAL H CG2 1 
ATOM   909  N N   . LYS B 2 13  ? 241.037 155.261 129.986 1.00 69.38  ? 13  LYS H N   1 
ATOM   910  C CA  . LYS B 2 13  ? 242.406 155.000 129.587 1.00 69.38  ? 13  LYS H CA  1 
ATOM   911  C C   . LYS B 2 13  ? 243.274 156.206 129.900 1.00 69.38  ? 13  LYS H C   1 
ATOM   912  O O   . LYS B 2 13  ? 242.769 157.322 130.041 1.00 69.38  ? 13  LYS H O   1 
ATOM   913  C CB  . LYS B 2 13  ? 242.463 154.672 128.099 1.00 69.38  ? 13  LYS H CB  1 
ATOM   914  C CG  . LYS B 2 13  ? 241.563 153.518 127.693 1.00 69.38  ? 13  LYS H CG  1 
ATOM   915  C CD  . LYS B 2 13  ? 242.042 152.865 126.410 1.00 69.38  ? 13  LYS H CD  1 
ATOM   916  C CE  . LYS B 2 13  ? 243.517 152.509 126.495 1.00 69.38  ? 13  LYS H CE  1 
ATOM   917  N NZ  . LYS B 2 13  ? 243.911 151.523 125.454 1.00 69.38  ? 13  LYS H NZ  1 
ATOM   918  N N   . PRO B 2 14  ? 244.583 156.018 130.047 1.00 71.84  ? 14  PRO H N   1 
ATOM   919  C CA  . PRO B 2 14  ? 245.455 157.165 130.313 1.00 71.84  ? 14  PRO H CA  1 
ATOM   920  C C   . PRO B 2 14  ? 245.361 158.191 129.198 1.00 71.84  ? 14  PRO H C   1 
ATOM   921  O O   . PRO B 2 14  ? 245.267 157.847 128.019 1.00 71.84  ? 14  PRO H O   1 
ATOM   922  C CB  . PRO B 2 14  ? 246.851 156.539 130.387 1.00 71.84  ? 14  PRO H CB  1 
ATOM   923  C CG  . PRO B 2 14  ? 246.603 155.133 130.781 1.00 71.84  ? 14  PRO H CG  1 
ATOM   924  C CD  . PRO B 2 14  ? 245.316 154.744 130.117 1.00 71.84  ? 14  PRO H CD  1 
ATOM   925  N N   . GLY B 2 15  ? 245.376 159.462 129.583 1.00 70.10  ? 15  GLY H N   1 
ATOM   926  C CA  . GLY B 2 15  ? 245.283 160.535 128.619 1.00 70.10  ? 15  GLY H CA  1 
ATOM   927  C C   . GLY B 2 15  ? 243.890 160.840 128.124 1.00 70.10  ? 15  GLY H C   1 
ATOM   928  O O   . GLY B 2 15  ? 243.744 161.640 127.195 1.00 70.10  ? 15  GLY H O   1 
ATOM   929  N N   . GLY B 2 16  ? 242.866 160.231 128.703 1.00 66.31  ? 16  GLY H N   1 
ATOM   930  C CA  . GLY B 2 16  ? 241.491 160.467 128.308 1.00 66.31  ? 16  GLY H CA  1 
ATOM   931  C C   . GLY B 2 16  ? 240.835 161.546 129.138 1.00 66.31  ? 16  GLY H C   1 
ATOM   932  O O   . GLY B 2 16  ? 241.493 162.450 129.659 1.00 66.31  ? 16  GLY H O   1 
ATOM   933  N N   . SER B 2 17  ? 239.514 161.453 129.261 1.00 62.96  ? 17  SER H N   1 
ATOM   934  C CA  . SER B 2 17  ? 238.767 162.388 130.086 1.00 62.96  ? 17  SER H CA  1 
ATOM   935  C C   . SER B 2 17  ? 237.477 161.728 130.549 1.00 62.96  ? 17  SER H C   1 
ATOM   936  O O   . SER B 2 17  ? 236.995 160.768 129.946 1.00 62.96  ? 17  SER H O   1 
ATOM   937  C CB  . SER B 2 17  ? 238.471 163.687 129.333 1.00 62.96  ? 17  SER H CB  1 
ATOM   938  O OG  . SER B 2 17  ? 237.648 163.445 128.209 1.00 62.96  ? 17  SER H OG  1 
ATOM   939  N N   . LEU B 2 18  ? 236.925 162.261 131.635 1.00 53.99  ? 18  LEU H N   1 
ATOM   940  C CA  . LEU B 2 18  ? 235.694 161.743 132.213 1.00 53.99  ? 18  LEU H CA  1 
ATOM   941  C C   . LEU B 2 18  ? 235.019 162.879 132.964 1.00 53.99  ? 18  LEU H C   1 
ATOM   942  O O   . LEU B 2 18  ? 235.659 163.867 133.330 1.00 53.99  ? 18  LEU H O   1 
ATOM   943  C CB  . LEU B 2 18  ? 235.972 160.548 133.131 1.00 53.99  ? 18  LEU H CB  1 
ATOM   944  C CG  . LEU B 2 18  ? 234.790 159.828 133.783 1.00 53.99  ? 18  LEU H CG  1 
ATOM   945  C CD1 . LEU B 2 18  ? 233.890 159.212 132.729 1.00 53.99  ? 18  LEU H CD1 1 
ATOM   946  C CD2 . LEU B 2 18  ? 235.279 158.767 134.750 1.00 53.99  ? 18  LEU H CD2 1 
ATOM   947  N N   . ARG B 2 19  ? 233.715 162.738 133.184 1.00 50.88  ? 19  ARG H N   1 
ATOM   948  C CA  . ARG B 2 19  ? 232.919 163.813 133.768 1.00 50.88  ? 19  ARG H CA  1 
ATOM   949  C C   . ARG B 2 19  ? 232.001 163.235 134.832 1.00 50.88  ? 19  ARG H C   1 
ATOM   950  O O   . ARG B 2 19  ? 230.966 162.650 134.505 1.00 50.88  ? 19  ARG H O   1 
ATOM   951  C CB  . ARG B 2 19  ? 232.113 164.530 132.692 1.00 50.88  ? 19  ARG H CB  1 
ATOM   952  C CG  . ARG B 2 19  ? 231.409 165.773 133.170 1.00 50.88  ? 19  ARG H CG  1 
ATOM   953  C CD  . ARG B 2 19  ? 230.821 166.528 132.002 1.00 50.88  ? 19  ARG H CD  1 
ATOM   954  N NE  . ARG B 2 19  ? 230.272 167.809 132.416 1.00 50.88  ? 19  ARG H NE  1 
ATOM   955  C CZ  . ARG B 2 19  ? 229.035 167.978 132.863 1.00 50.88  ? 19  ARG H CZ  1 
ATOM   956  N NH1 . ARG B 2 19  ? 228.215 166.942 132.958 1.00 50.88  ? 19  ARG H NH1 1 
ATOM   957  N NH2 . ARG B 2 19  ? 228.621 169.183 133.216 1.00 50.88  ? 19  ARG H NH2 1 
ATOM   958  N N   . LEU B 2 20  ? 232.365 163.407 136.096 1.00 47.35  ? 20  LEU H N   1 
ATOM   959  C CA  . LEU B 2 20  ? 231.549 162.931 137.200 1.00 47.35  ? 20  LEU H CA  1 
ATOM   960  C C   . LEU B 2 20  ? 230.494 163.963 137.558 1.00 47.35  ? 20  LEU H C   1 
ATOM   961  O O   . LEU B 2 20  ? 230.613 165.145 137.236 1.00 47.35  ? 20  LEU H O   1 
ATOM   962  C CB  . LEU B 2 20  ? 232.401 162.627 138.430 1.00 47.35  ? 20  LEU H CB  1 
ATOM   963  C CG  . LEU B 2 20  ? 233.214 161.336 138.491 1.00 47.35  ? 20  LEU H CG  1 
ATOM   964  C CD1 . LEU B 2 20  ? 234.393 161.373 137.553 1.00 47.35  ? 20  LEU H CD1 1 
ATOM   965  C CD2 . LEU B 2 20  ? 233.676 161.096 139.907 1.00 47.35  ? 20  LEU H CD2 1 
ATOM   966  N N   . SER B 2 21  ? 229.454 163.500 138.244 1.00 52.04  ? 21  SER H N   1 
ATOM   967  C CA  . SER B 2 21  ? 228.387 164.384 138.685 1.00 52.04  ? 21  SER H CA  1 
ATOM   968  C C   . SER B 2 21  ? 227.685 163.753 139.875 1.00 52.04  ? 21  SER H C   1 
ATOM   969  O O   . SER B 2 21  ? 227.685 162.531 140.029 1.00 52.04  ? 21  SER H O   1 
ATOM   970  C CB  . SER B 2 21  ? 227.382 164.653 137.561 1.00 52.04  ? 21  SER H CB  1 
ATOM   971  O OG  . SER B 2 21  ? 226.624 163.496 137.267 1.00 52.04  ? 21  SER H OG  1 
ATOM   972  N N   . CYS B 2 22  ? 227.092 164.597 140.716 1.00 55.12  ? 22  CYS H N   1 
ATOM   973  C CA  . CYS B 2 22  ? 226.256 164.113 141.805 1.00 55.12  ? 22  CYS H CA  1 
ATOM   974  C C   . CYS B 2 22  ? 225.077 165.050 141.982 1.00 55.12  ? 22  CYS H C   1 
ATOM   975  O O   . CYS B 2 22  ? 225.244 166.270 141.979 1.00 55.12  ? 22  CYS H O   1 
ATOM   976  C CB  . CYS B 2 22  ? 227.039 163.975 143.119 1.00 55.12  ? 22  CYS H CB  1 
ATOM   977  S SG  . CYS B 2 22  ? 227.486 165.457 144.069 1.00 55.12  ? 22  CYS H SG  1 
ATOM   978  N N   . ALA B 2 23  ? 223.890 164.471 142.125 1.00 66.09  ? 23  ALA H N   1 
ATOM   979  C CA  . ALA B 2 23  ? 222.654 165.217 142.296 1.00 66.09  ? 23  ALA H CA  1 
ATOM   980  C C   . ALA B 2 23  ? 222.170 165.082 143.731 1.00 66.09  ? 23  ALA H C   1 
ATOM   981  O O   . ALA B 2 23  ? 222.197 163.991 144.306 1.00 66.09  ? 23  ALA H O   1 
ATOM   982  C CB  . ALA B 2 23  ? 221.575 164.721 141.332 1.00 66.09  ? 23  ALA H CB  1 
ATOM   983  N N   . ALA B 2 24  ? 221.725 166.191 144.305 1.00 70.87  ? 24  ALA H N   1 
ATOM   984  C CA  . ALA B 2 24  ? 221.320 166.234 145.698 1.00 70.87  ? 24  ALA H CA  1 
ATOM   985  C C   . ALA B 2 24  ? 219.844 166.579 145.807 1.00 70.87  ? 24  ALA H C   1 
ATOM   986  O O   . ALA B 2 24  ? 219.286 167.278 144.957 1.00 70.87  ? 24  ALA H O   1 
ATOM   987  C CB  . ALA B 2 24  ? 222.146 167.256 146.477 1.00 70.87  ? 24  ALA H CB  1 
ATOM   988  N N   . SER B 2 25  ? 219.215 166.078 146.866 1.00 73.11  ? 25  SER H N   1 
ATOM   989  C CA  . SER B 2 25  ? 217.817 166.376 147.133 1.00 73.11  ? 25  SER H CA  1 
ATOM   990  C C   . SER B 2 25  ? 217.593 166.403 148.635 1.00 73.11  ? 25  SER H C   1 
ATOM   991  O O   . SER B 2 25  ? 218.322 165.765 149.398 1.00 73.11  ? 25  SER H O   1 
ATOM   992  C CB  . SER B 2 25  ? 216.887 165.351 146.476 1.00 73.11  ? 25  SER H CB  1 
ATOM   993  O OG  . SER B 2 25  ? 217.084 164.061 147.026 1.00 73.11  ? 25  SER H OG  1 
ATOM   994  N N   . GLY B 2 26  ? 216.571 167.140 149.050 1.00 69.98  ? 26  GLY H N   1 
ATOM   995  C CA  . GLY B 2 26  ? 216.217 167.236 150.447 1.00 69.98  ? 26  GLY H CA  1 
ATOM   996  C C   . GLY B 2 26  ? 216.626 168.511 151.148 1.00 69.98  ? 26  GLY H C   1 
ATOM   997  O O   . GLY B 2 26  ? 216.433 168.609 152.364 1.00 69.98  ? 26  GLY H O   1 
ATOM   998  N N   . PHE B 2 27  ? 217.182 169.485 150.434 1.00 62.36  ? 27  PHE H N   1 
ATOM   999  C CA  . PHE B 2 27  ? 217.537 170.760 151.042 1.00 62.36  ? 27  PHE H CA  1 
ATOM   1000 C C   . PHE B 2 27  ? 217.596 171.823 149.957 1.00 62.36  ? 27  PHE H C   1 
ATOM   1001 O O   . PHE B 2 27  ? 217.537 171.525 148.763 1.00 62.36  ? 27  PHE H O   1 
ATOM   1002 C CB  . PHE B 2 27  ? 218.868 170.680 151.802 1.00 62.36  ? 27  PHE H CB  1 
ATOM   1003 C CG  . PHE B 2 27  ? 220.004 170.092 151.004 1.00 62.36  ? 27  PHE H CG  1 
ATOM   1004 C CD1 . PHE B 2 27  ? 220.536 170.761 149.920 1.00 62.36  ? 27  PHE H CD1 1 
ATOM   1005 C CD2 . PHE B 2 27  ? 220.562 168.885 151.365 1.00 62.36  ? 27  PHE H CD2 1 
ATOM   1006 C CE1 . PHE B 2 27  ? 221.577 170.223 149.204 1.00 62.36  ? 27  PHE H CE1 1 
ATOM   1007 C CE2 . PHE B 2 27  ? 221.606 168.351 150.651 1.00 62.36  ? 27  PHE H CE2 1 
ATOM   1008 C CZ  . PHE B 2 27  ? 222.111 169.020 149.572 1.00 62.36  ? 27  PHE H CZ  1 
ATOM   1009 N N   . ARG B 2 28  ? 217.714 173.073 150.392 1.00 65.13  ? 28  ARG H N   1 
ATOM   1010 C CA  . ARG B 2 28  ? 217.974 174.175 149.471 1.00 65.13  ? 28  ARG H CA  1 
ATOM   1011 C C   . ARG B 2 28  ? 219.416 174.059 149.009 1.00 65.13  ? 28  ARG H C   1 
ATOM   1012 O O   . ARG B 2 28  ? 220.345 174.400 149.741 1.00 65.13  ? 28  ARG H O   1 
ATOM   1013 C CB  . ARG B 2 28  ? 217.720 175.518 150.142 1.00 65.13  ? 28  ARG H CB  1 
ATOM   1014 C CG  . ARG B 2 28  ? 216.291 175.750 150.574 1.00 65.13  ? 28  ARG H CG  1 
ATOM   1015 C CD  . ARG B 2 28  ? 216.174 177.059 151.330 1.00 65.13  ? 28  ARG H CD  1 
ATOM   1016 N NE  . ARG B 2 28  ? 214.788 177.411 151.621 1.00 65.13  ? 28  ARG H NE  1 
ATOM   1017 C CZ  . ARG B 2 28  ? 214.420 178.455 152.358 1.00 65.13  ? 28  ARG H CZ  1 
ATOM   1018 N NH1 . ARG B 2 28  ? 213.134 178.699 152.569 1.00 65.13  ? 28  ARG H NH1 1 
ATOM   1019 N NH2 . ARG B 2 28  ? 215.336 179.258 152.884 1.00 65.13  ? 28  ARG H NH2 1 
ATOM   1020 N N   . PHE B 2 29  ? 219.616 173.565 147.790 1.00 51.49  ? 29  PHE H N   1 
ATOM   1021 C CA  . PHE B 2 29  ? 220.970 173.310 147.327 1.00 51.49  ? 29  PHE H CA  1 
ATOM   1022 C C   . PHE B 2 29  ? 221.729 174.582 147.003 1.00 51.49  ? 29  PHE H C   1 
ATOM   1023 O O   . PHE B 2 29  ? 222.961 174.562 146.989 1.00 51.49  ? 29  PHE H O   1 
ATOM   1024 C CB  . PHE B 2 29  ? 220.944 172.413 146.099 1.00 51.49  ? 29  PHE H CB  1 
ATOM   1025 C CG  . PHE B 2 29  ? 222.293 172.124 145.537 1.00 51.49  ? 29  PHE H CG  1 
ATOM   1026 C CD1 . PHE B 2 29  ? 223.144 171.255 146.176 1.00 51.49  ? 29  PHE H CD1 1 
ATOM   1027 C CD2 . PHE B 2 29  ? 222.704 172.715 144.366 1.00 51.49  ? 29  PHE H CD2 1 
ATOM   1028 C CE1 . PHE B 2 29  ? 224.379 170.985 145.659 1.00 51.49  ? 29  PHE H CE1 1 
ATOM   1029 C CE2 . PHE B 2 29  ? 223.938 172.445 143.844 1.00 51.49  ? 29  PHE H CE2 1 
ATOM   1030 C CZ  . PHE B 2 29  ? 224.776 171.579 144.490 1.00 51.49  ? 29  PHE H CZ  1 
ATOM   1031 N N   . SER B 2 30  ? 221.037 175.686 146.756 1.00 52.05  ? 30  SER H N   1 
ATOM   1032 C CA  . SER B 2 30  ? 221.711 176.880 146.271 1.00 52.05  ? 30  SER H CA  1 
ATOM   1033 C C   . SER B 2 30  ? 222.300 177.737 147.377 1.00 52.05  ? 30  SER H C   1 
ATOM   1034 O O   . SER B 2 30  ? 222.753 178.846 147.091 1.00 52.05  ? 30  SER H O   1 
ATOM   1035 C CB  . SER B 2 30  ? 220.752 177.728 145.443 1.00 52.05  ? 30  SER H CB  1 
ATOM   1036 O OG  . SER B 2 30  ? 221.427 178.856 144.924 1.00 52.05  ? 30  SER H OG  1 
ATOM   1037 N N   . ASP B 2 31  ? 222.296 177.272 148.623 1.00 53.70  ? 31  ASP H N   1 
ATOM   1038 C CA  . ASP B 2 31  ? 222.799 178.064 149.738 1.00 53.70  ? 31  ASP H CA  1 
ATOM   1039 C C   . ASP B 2 31  ? 223.998 177.434 150.427 1.00 53.70  ? 31  ASP H C   1 
ATOM   1040 O O   . ASP B 2 31  ? 224.462 177.969 151.439 1.00 53.70  ? 31  ASP H O   1 
ATOM   1041 C CB  . ASP B 2 31  ? 221.694 178.299 150.769 1.00 53.70  ? 31  ASP H CB  1 
ATOM   1042 C CG  . ASP B 2 31  ? 220.482 178.976 150.179 1.00 53.70  ? 31  ASP H CG  1 
ATOM   1043 O OD1 . ASP B 2 31  ? 219.436 179.012 150.857 1.00 53.70  ? 31  ASP H OD1 1 
ATOM   1044 O OD2 . ASP B 2 31  ? 220.578 179.486 149.045 1.00 53.70  ? 31  ASP H OD2 1 
ATOM   1045 N N   . TYR B 2 32  ? 224.515 176.324 149.918 1.00 44.21  ? 32  TYR H N   1 
ATOM   1046 C CA  . TYR B 2 32  ? 225.547 175.572 150.611 1.00 44.21  ? 32  TYR H CA  1 
ATOM   1047 C C   . TYR B 2 32  ? 226.791 175.451 149.748 1.00 44.21  ? 32  TYR H C   1 
ATOM   1048 O O   . TYR B 2 32  ? 226.701 175.336 148.523 1.00 44.21  ? 32  TYR H O   1 
ATOM   1049 C CB  . TYR B 2 32  ? 225.042 174.183 150.988 1.00 44.21  ? 32  TYR H CB  1 
ATOM   1050 C CG  . TYR B 2 32  ? 224.013 174.198 152.085 1.00 44.21  ? 32  TYR H CG  1 
ATOM   1051 C CD1 . TYR B 2 32  ? 222.674 174.383 151.799 1.00 44.21  ? 32  TYR H CD1 1 
ATOM   1052 C CD2 . TYR B 2 32  ? 224.381 174.033 153.408 1.00 44.21  ? 32  TYR H CD2 1 
ATOM   1053 C CE1 . TYR B 2 32  ? 221.732 174.400 152.799 1.00 44.21  ? 32  TYR H CE1 1 
ATOM   1054 C CE2 . TYR B 2 32  ? 223.446 174.050 154.415 1.00 44.21  ? 32  TYR H CE2 1 
ATOM   1055 C CZ  . TYR B 2 32  ? 222.124 174.233 154.104 1.00 44.21  ? 32  TYR H CZ  1 
ATOM   1056 O OH  . TYR B 2 32  ? 221.186 174.250 155.104 1.00 44.21  ? 32  TYR H OH  1 
ATOM   1057 N N   . TYR B 2 33  ? 227.951 175.490 150.395 1.00 36.51  ? 33  TYR H N   1 
ATOM   1058 C CA  . TYR B 2 33  ? 229.181 175.128 149.718 1.00 36.51  ? 33  TYR H CA  1 
ATOM   1059 C C   . TYR B 2 33  ? 229.133 173.656 149.356 1.00 36.51  ? 33  TYR H C   1 
ATOM   1060 O O   . TYR B 2 33  ? 228.477 172.858 150.023 1.00 36.51  ? 33  TYR H O   1 
ATOM   1061 C CB  . TYR B 2 33  ? 230.395 175.376 150.608 1.00 36.51  ? 33  TYR H CB  1 
ATOM   1062 C CG  . TYR B 2 33  ? 230.507 176.747 151.224 1.00 36.51  ? 33  TYR H CG  1 
ATOM   1063 C CD1 . TYR B 2 33  ? 229.843 177.836 150.691 1.00 36.51  ? 33  TYR H CD1 1 
ATOM   1064 C CD2 . TYR B 2 33  ? 231.298 176.951 152.337 1.00 36.51  ? 33  TYR H CD2 1 
ATOM   1065 C CE1 . TYR B 2 33  ? 229.959 179.084 151.260 1.00 36.51  ? 33  TYR H CE1 1 
ATOM   1066 C CE2 . TYR B 2 33  ? 231.419 178.189 152.909 1.00 36.51  ? 33  TYR H CE2 1 
ATOM   1067 C CZ  . TYR B 2 33  ? 230.749 179.252 152.369 1.00 36.51  ? 33  TYR H CZ  1 
ATOM   1068 O OH  . TYR B 2 33  ? 230.871 180.491 152.944 1.00 36.51  ? 33  TYR H OH  1 
ATOM   1069 N N   . MET B 2 34  ? 229.829 173.291 148.289 1.00 31.81  ? 34  MET H N   1 
ATOM   1070 C CA  . MET B 2 34  ? 230.005 171.887 147.962 1.00 31.81  ? 34  MET H CA  1 
ATOM   1071 C C   . MET B 2 34  ? 231.423 171.689 147.466 1.00 31.81  ? 34  MET H C   1 
ATOM   1072 O O   . MET B 2 34  ? 232.061 172.626 146.990 1.00 31.81  ? 34  MET H O   1 
ATOM   1073 C CB  . MET B 2 34  ? 229.011 171.400 146.910 1.00 31.81  ? 34  MET H CB  1 
ATOM   1074 C CG  . MET B 2 34  ? 227.559 171.554 147.285 1.00 31.81  ? 34  MET H CG  1 
ATOM   1075 S SD  . MET B 2 34  ? 226.886 170.064 148.020 1.00 31.81  ? 34  MET H SD  1 
ATOM   1076 C CE  . MET B 2 34  ? 227.081 168.936 146.654 1.00 31.81  ? 34  MET H CE  1 
ATOM   1077 N N   . ASN B 2 35  ? 231.908 170.457 147.564 1.00 23.36  ? 35  ASN H N   1 
ATOM   1078 C CA  . ASN B 2 35  ? 233.311 170.201 147.286 1.00 23.36  ? 35  ASN H CA  1 
ATOM   1079 C C   . ASN B 2 35  ? 233.603 168.714 147.332 1.00 23.36  ? 35  ASN H C   1 
ATOM   1080 O O   . ASN B 2 35  ? 232.908 167.961 148.011 1.00 23.36  ? 35  ASN H O   1 
ATOM   1081 C CB  . ASN B 2 35  ? 234.177 170.994 148.260 1.00 23.36  ? 35  ASN H CB  1 
ATOM   1082 C CG  . ASN B 2 35  ? 233.879 170.674 149.681 1.00 23.36  ? 35  ASN H CG  1 
ATOM   1083 O OD1 . ASN B 2 35  ? 233.122 169.765 149.975 1.00 23.36  ? 35  ASN H OD1 1 
ATOM   1084 N ND2 . ASN B 2 35  ? 234.404 171.485 150.582 1.00 23.36  ? 35  ASN H ND2 1 
ATOM   1085 N N   . TRP B 2 36  ? 234.634 168.304 146.595 1.00 22.90  ? 36  TRP H N   1 
ATOM   1086 C CA  . TRP B 2 36  ? 234.897 166.901 146.293 1.00 22.90  ? 36  TRP H CA  1 
ATOM   1087 C C   . TRP B 2 36  ? 236.095 166.389 147.077 1.00 22.90  ? 36  TRP H C   1 
ATOM   1088 O O   . TRP B 2 36  ? 237.203 166.906 146.927 1.00 22.90  ? 36  TRP H O   1 
ATOM   1089 C CB  . TRP B 2 36  ? 235.160 166.705 144.804 1.00 22.90  ? 36  TRP H CB  1 
ATOM   1090 C CG  . TRP B 2 36  ? 233.986 166.934 143.953 1.00 22.90  ? 36  TRP H CG  1 
ATOM   1091 C CD1 . TRP B 2 36  ? 233.474 168.128 143.592 1.00 22.90  ? 36  TRP H CD1 1 
ATOM   1092 C CD2 . TRP B 2 36  ? 233.166 165.939 143.340 1.00 22.90  ? 36  TRP H CD2 1 
ATOM   1093 N NE1 . TRP B 2 36  ? 232.384 167.949 142.790 1.00 22.90  ? 36  TRP H NE1 1 
ATOM   1094 C CE2 . TRP B 2 36  ? 232.170 166.608 142.627 1.00 22.90  ? 36  TRP H CE2 1 
ATOM   1095 C CE3 . TRP B 2 36  ? 233.175 164.547 143.332 1.00 22.90  ? 36  TRP H CE3 1 
ATOM   1096 C CZ2 . TRP B 2 36  ? 231.195 165.939 141.913 1.00 22.90  ? 36  TRP H CZ2 1 
ATOM   1097 C CZ3 . TRP B 2 36  ? 232.208 163.886 142.626 1.00 22.90  ? 36  TRP H CZ3 1 
ATOM   1098 C CH2 . TRP B 2 36  ? 231.233 164.577 141.925 1.00 22.90  ? 36  TRP H CH2 1 
ATOM   1099 N N   . ILE B 2 37  ? 235.882 165.340 147.856 1.00 20.67  ? 37  ILE H N   1 
ATOM   1100 C CA  . ILE B 2 37  ? 236.954 164.620 148.497 1.00 20.67  ? 37  ILE H CA  1 
ATOM   1101 C C   . ILE B 2 37  ? 237.336 163.457 147.591 1.00 20.67  ? 37  ILE H C   1 
ATOM   1102 O O   . ILE B 2 37  ? 236.650 163.149 146.624 1.00 20.67  ? 37  ILE H O   1 
ATOM   1103 C CB  . ILE B 2 37  ? 236.548 164.129 149.897 1.00 20.67  ? 37  ILE H CB  1 
ATOM   1104 C CG1 . ILE B 2 37  ? 235.704 165.177 150.590 1.00 20.67  ? 37  ILE H CG1 1 
ATOM   1105 C CG2 . ILE B 2 37  ? 237.748 163.884 150.735 1.00 20.67  ? 37  ILE H CG2 1 
ATOM   1106 C CD1 . ILE B 2 37  ? 236.438 166.440 150.831 1.00 20.67  ? 37  ILE H CD1 1 
ATOM   1107 N N   . ARG B 2 38  ? 238.458 162.813 147.888 1.00 21.27  ? 38  ARG H N   1 
ATOM   1108 C CA  . ARG B 2 38  ? 238.831 161.615 147.156 1.00 21.27  ? 38  ARG H CA  1 
ATOM   1109 C C   . ARG B 2 38  ? 239.686 160.746 148.055 1.00 21.27  ? 38  ARG H C   1 
ATOM   1110 O O   . ARG B 2 38  ? 240.261 161.222 149.033 1.00 21.27  ? 38  ARG H O   1 
ATOM   1111 C CB  . ARG B 2 38  ? 239.573 161.951 145.871 1.00 21.27  ? 38  ARG H CB  1 
ATOM   1112 C CG  . ARG B 2 38  ? 241.059 161.953 146.006 1.00 21.27  ? 38  ARG H CG  1 
ATOM   1113 C CD  . ARG B 2 38  ? 241.684 161.989 144.644 1.00 21.27  ? 38  ARG H CD  1 
ATOM   1114 N NE  . ARG B 2 38  ? 243.101 162.298 144.702 1.00 21.27  ? 38  ARG H NE  1 
ATOM   1115 C CZ  . ARG B 2 38  ? 243.853 162.493 143.631 1.00 21.27  ? 38  ARG H CZ  1 
ATOM   1116 N NH1 . ARG B 2 38  ? 243.317 162.410 142.425 1.00 21.27  ? 38  ARG H NH1 1 
ATOM   1117 N NH2 . ARG B 2 38  ? 245.139 162.771 143.762 1.00 21.27  ? 38  ARG H NH2 1 
ATOM   1118 N N   . GLN B 2 39  ? 239.764 159.461 147.722 1.00 29.02  ? 39  GLN H N   1 
ATOM   1119 C CA  . GLN B 2 39  ? 240.499 158.506 148.540 1.00 29.02  ? 39  GLN H CA  1 
ATOM   1120 C C   . GLN B 2 39  ? 241.212 157.509 147.652 1.00 29.02  ? 39  GLN H C   1 
ATOM   1121 O O   . GLN B 2 39  ? 240.563 156.737 146.946 1.00 29.02  ? 39  GLN H O   1 
ATOM   1122 C CB  . GLN B 2 39  ? 239.571 157.762 149.497 1.00 29.02  ? 39  GLN H CB  1 
ATOM   1123 C CG  . GLN B 2 39  ? 240.292 156.721 150.322 1.00 29.02  ? 39  GLN H CG  1 
ATOM   1124 C CD  . GLN B 2 39  ? 239.447 156.164 151.440 1.00 29.02  ? 39  GLN H CD  1 
ATOM   1125 O OE1 . GLN B 2 39  ? 238.233 156.040 151.314 1.00 29.02  ? 39  GLN H OE1 1 
ATOM   1126 N NE2 . GLN B 2 39  ? 240.086 155.842 152.555 1.00 29.02  ? 39  GLN H NE2 1 
ATOM   1127 N N   . ALA B 2 40  ? 242.538 157.498 147.711 1.00 35.25  ? 40  ALA H N   1 
ATOM   1128 C CA  . ALA B 2 40  ? 243.289 156.460 147.037 1.00 35.25  ? 40  ALA H CA  1 
ATOM   1129 C C   . ALA B 2 40  ? 242.974 155.116 147.686 1.00 35.25  ? 40  ALA H C   1 
ATOM   1130 O O   . ALA B 2 40  ? 242.512 155.068 148.825 1.00 35.25  ? 40  ALA H O   1 
ATOM   1131 C CB  . ALA B 2 40  ? 244.784 156.758 147.107 1.00 35.25  ? 40  ALA H CB  1 
ATOM   1132 N N   . PRO B 2 41  ? 243.184 154.009 146.978 1.00 41.41  ? 41  PRO H N   1 
ATOM   1133 C CA  . PRO B 2 41  ? 242.821 152.710 147.556 1.00 41.41  ? 41  PRO H CA  1 
ATOM   1134 C C   . PRO B 2 41  ? 243.699 152.333 148.737 1.00 41.41  ? 41  PRO H C   1 
ATOM   1135 O O   . PRO B 2 41  ? 244.869 151.980 148.565 1.00 41.41  ? 41  PRO H O   1 
ATOM   1136 C CB  . PRO B 2 41  ? 243.011 151.737 146.386 1.00 41.41  ? 41  PRO H CB  1 
ATOM   1137 C CG  . PRO B 2 41  ? 243.017 152.587 145.171 1.00 41.41  ? 41  PRO H CG  1 
ATOM   1138 C CD  . PRO B 2 41  ? 243.645 153.870 145.591 1.00 41.41  ? 41  PRO H CD  1 
ATOM   1139 N N   . GLY B 2 42  ? 243.137 152.392 149.941 1.00 39.45  ? 42  GLY H N   1 
ATOM   1140 C CA  . GLY B 2 42  ? 243.874 152.028 151.131 1.00 39.45  ? 42  GLY H CA  1 
ATOM   1141 C C   . GLY B 2 42  ? 244.788 153.093 151.689 1.00 39.45  ? 42  GLY H C   1 
ATOM   1142 O O   . GLY B 2 42  ? 245.754 152.758 152.377 1.00 39.45  ? 42  GLY H O   1 
ATOM   1143 N N   . LYS B 2 43  ? 244.520 154.366 151.415 1.00 37.61  ? 43  LYS H N   1 
ATOM   1144 C CA  . LYS B 2 43  ? 245.291 155.475 151.958 1.00 37.61  ? 43  LYS H CA  1 
ATOM   1145 C C   . LYS B 2 43  ? 244.338 156.473 152.601 1.00 37.61  ? 43  LYS H C   1 
ATOM   1146 O O   . LYS B 2 43  ? 243.130 156.243 152.696 1.00 37.61  ? 43  LYS H O   1 
ATOM   1147 C CB  . LYS B 2 43  ? 246.135 156.156 150.875 1.00 37.61  ? 43  LYS H CB  1 
ATOM   1148 C CG  . LYS B 2 43  ? 246.695 155.211 149.831 1.00 37.61  ? 43  LYS H CG  1 
ATOM   1149 C CD  . LYS B 2 43  ? 247.736 154.285 150.419 1.00 37.61  ? 43  LYS H CD  1 
ATOM   1150 C CE  . LYS B 2 43  ? 248.982 155.057 150.792 1.00 37.61  ? 43  LYS H CE  1 
ATOM   1151 N NZ  . LYS B 2 43  ? 249.398 155.964 149.688 1.00 37.61  ? 43  LYS H NZ  1 
ATOM   1152 N N   . GLY B 2 44  ? 244.889 157.593 153.047 1.00 30.81  ? 44  GLY H N   1 
ATOM   1153 C CA  . GLY B 2 44  ? 244.078 158.600 153.690 1.00 30.81  ? 44  GLY H CA  1 
ATOM   1154 C C   . GLY B 2 44  ? 243.340 159.475 152.700 1.00 30.81  ? 44  GLY H C   1 
ATOM   1155 O O   . GLY B 2 44  ? 243.736 159.626 151.549 1.00 30.81  ? 44  GLY H O   1 
ATOM   1156 N N   . LEU B 2 45  ? 242.242 160.060 153.169 1.00 20.38  ? 45  LEU H N   1 
ATOM   1157 C CA  . LEU B 2 45  ? 241.465 160.947 152.323 1.00 20.38  ? 45  LEU H CA  1 
ATOM   1158 C C   . LEU B 2 45  ? 242.316 162.133 151.901 1.00 20.38  ? 45  LEU H C   1 
ATOM   1159 O O   . LEU B 2 45  ? 243.170 162.606 152.651 1.00 20.38  ? 45  LEU H O   1 
ATOM   1160 C CB  . LEU B 2 45  ? 240.224 161.442 153.059 1.00 20.38  ? 45  LEU H CB  1 
ATOM   1161 C CG  . LEU B 2 45  ? 239.216 160.440 153.605 1.00 20.38  ? 45  LEU H CG  1 
ATOM   1162 C CD1 . LEU B 2 45  ? 237.932 161.143 153.950 1.00 20.38  ? 45  LEU H CD1 1 
ATOM   1163 C CD2 . LEU B 2 45  ? 238.956 159.379 152.596 1.00 20.38  ? 45  LEU H CD2 1 
ATOM   1164 N N   . GLU B 2 46  ? 242.094 162.602 150.680 1.00 17.74  ? 46  GLU H N   1 
ATOM   1165 C CA  . GLU B 2 46  ? 242.730 163.811 150.184 1.00 17.74  ? 46  GLU H CA  1 
ATOM   1166 C C   . GLU B 2 46  ? 241.654 164.725 149.629 1.00 17.74  ? 46  GLU H C   1 
ATOM   1167 O O   . GLU B 2 46  ? 240.659 164.251 149.080 1.00 17.74  ? 46  GLU H O   1 
ATOM   1168 C CB  . GLU B 2 46  ? 243.764 163.505 149.105 1.00 17.74  ? 46  GLU H CB  1 
ATOM   1169 C CG  . GLU B 2 46  ? 244.573 164.714 148.680 1.00 17.74  ? 46  GLU H CG  1 
ATOM   1170 C CD  . GLU B 2 46  ? 245.322 164.497 147.382 1.00 17.74  ? 46  GLU H CD  1 
ATOM   1171 O OE1 . GLU B 2 46  ? 246.167 165.346 147.029 1.00 17.74  ? 46  GLU H OE1 1 
ATOM   1172 O OE2 . GLU B 2 46  ? 245.064 163.479 146.711 1.00 17.74  ? 46  GLU H OE2 1 
ATOM   1173 N N   . TRP B 2 47  ? 241.843 166.028 149.786 1.00 20.46  ? 47  TRP H N   1 
ATOM   1174 C CA  . TRP B 2 47  ? 240.874 167.013 149.329 1.00 20.46  ? 47  TRP H CA  1 
ATOM   1175 C C   . TRP B 2 47  ? 241.231 167.473 147.920 1.00 20.46  ? 47  TRP H C   1 
ATOM   1176 O O   . TRP B 2 47  ? 242.408 167.593 147.580 1.00 20.46  ? 47  TRP H O   1 
ATOM   1177 C CB  . TRP B 2 47  ? 240.842 168.186 150.304 1.00 20.46  ? 47  TRP H CB  1 
ATOM   1178 C CG  . TRP B 2 47  ? 240.073 169.358 149.847 1.00 20.46  ? 47  TRP H CG  1 
ATOM   1179 C CD1 . TRP B 2 47  ? 238.765 169.618 150.083 1.00 20.46  ? 47  TRP H CD1 1 
ATOM   1180 C CD2 . TRP B 2 47  ? 240.572 170.461 149.095 1.00 20.46  ? 47  TRP H CD2 1 
ATOM   1181 N NE1 . TRP B 2 47  ? 238.409 170.808 149.511 1.00 20.46  ? 47  TRP H NE1 1 
ATOM   1182 C CE2 . TRP B 2 47  ? 239.507 171.345 148.897 1.00 20.46  ? 47  TRP H CE2 1 
ATOM   1183 C CE3 . TRP B 2 47  ? 241.819 170.783 148.561 1.00 20.46  ? 47  TRP H CE3 1 
ATOM   1184 C CZ2 . TRP B 2 47  ? 239.647 172.523 148.195 1.00 20.46  ? 47  TRP H CZ2 1 
ATOM   1185 C CZ3 . TRP B 2 47  ? 241.954 171.953 147.865 1.00 20.46  ? 47  TRP H CZ3 1 
ATOM   1186 C CH2 . TRP B 2 47  ? 240.879 172.809 147.686 1.00 20.46  ? 47  TRP H CH2 1 
ATOM   1187 N N   . ILE B 2 48  ? 240.211 167.715 147.093 1.00 18.47  ? 48  ILE H N   1 
ATOM   1188 C CA  . ILE B 2 48  ? 240.435 167.933 145.666 1.00 18.47  ? 48  ILE H CA  1 
ATOM   1189 C C   . ILE B 2 48  ? 239.871 169.243 145.129 1.00 18.47  ? 48  ILE H C   1 
ATOM   1190 O O   . ILE B 2 48  ? 240.593 170.009 144.485 1.00 18.47  ? 48  ILE H O   1 
ATOM   1191 C CB  . ILE B 2 48  ? 239.890 166.756 144.855 1.00 18.47  ? 48  ILE H CB  1 
ATOM   1192 C CG1 . ILE B 2 48  ? 240.838 165.590 145.000 1.00 18.47  ? 48  ILE H CG1 1 
ATOM   1193 C CG2 . ILE B 2 48  ? 239.798 167.110 143.411 1.00 18.47  ? 48  ILE H CG2 1 
ATOM   1194 C CD1 . ILE B 2 48  ? 242.205 165.916 144.473 1.00 18.47  ? 48  ILE H CD1 1 
ATOM   1195 N N   . SER B 2 49  ? 238.591 169.510 145.346 1.00 18.73  ? 49  SER H N   1 
ATOM   1196 C CA  . SER B 2 49  ? 237.987 170.686 144.741 1.00 18.73  ? 49  SER H CA  1 
ATOM   1197 C C   . SER B 2 49  ? 237.174 171.450 145.771 1.00 18.73  ? 49  SER H C   1 
ATOM   1198 O O   . SER B 2 49  ? 237.141 171.102 146.951 1.00 18.73  ? 49  SER H O   1 
ATOM   1199 C CB  . SER B 2 49  ? 237.116 170.303 143.549 1.00 18.73  ? 49  SER H CB  1 
ATOM   1200 O OG  . SER B 2 49  ? 236.427 171.439 143.080 1.00 18.73  ? 49  SER H OG  1 
ATOM   1201 N N   . TYR B 2 50  ? 236.531 172.520 145.312 1.00 20.19  ? 50  TYR H N   1 
ATOM   1202 C CA  . TYR B 2 50  ? 235.694 173.363 146.151 1.00 20.19  ? 50  TYR H CA  1 
ATOM   1203 C C   . TYR B 2 50  ? 234.953 174.330 145.252 1.00 20.19  ? 50  TYR H C   1 
ATOM   1204 O O   . TYR B 2 50  ? 235.540 174.880 144.324 1.00 20.19  ? 50  TYR H O   1 
ATOM   1205 C CB  . TYR B 2 50  ? 236.529 174.131 147.181 1.00 20.19  ? 50  TYR H CB  1 
ATOM   1206 C CG  . TYR B 2 50  ? 235.796 175.207 147.954 1.00 20.19  ? 50  TYR H CG  1 
ATOM   1207 C CD1 . TYR B 2 50  ? 235.202 174.933 149.166 1.00 20.19  ? 50  TYR H CD1 1 
ATOM   1208 C CD2 . TYR B 2 50  ? 235.731 176.500 147.484 1.00 20.19  ? 50  TYR H CD2 1 
ATOM   1209 C CE1 . TYR B 2 50  ? 234.548 175.915 149.872 1.00 20.19  ? 50  TYR H CE1 1 
ATOM   1210 C CE2 . TYR B 2 50  ? 235.079 177.483 148.183 1.00 20.19  ? 50  TYR H CE2 1 
ATOM   1211 C CZ  . TYR B 2 50  ? 234.490 177.188 149.370 1.00 20.19  ? 50  TYR H CZ  1 
ATOM   1212 O OH  . TYR B 2 50  ? 233.845 178.181 150.061 1.00 20.19  ? 50  TYR H OH  1 
ATOM   1213 N N   . ILE B 2 51  ? 233.671 174.528 145.528 1.00 22.14  ? 51  ILE H N   1 
ATOM   1214 C CA  . ILE B 2 51  ? 232.872 175.518 144.818 1.00 22.14  ? 51  ILE H CA  1 
ATOM   1215 C C   . ILE B 2 51  ? 232.180 176.382 145.859 1.00 22.14  ? 51  ILE H C   1 
ATOM   1216 O O   . ILE B 2 51  ? 232.045 175.979 147.015 1.00 22.14  ? 51  ILE H O   1 
ATOM   1217 C CB  . ILE B 2 51  ? 231.875 174.843 143.863 1.00 22.14  ? 51  ILE H CB  1 
ATOM   1218 C CG1 . ILE B 2 51  ? 231.233 175.860 142.926 1.00 22.14  ? 51  ILE H CG1 1 
ATOM   1219 C CG2 . ILE B 2 51  ? 230.822 174.116 144.632 1.00 22.14  ? 51  ILE H CG2 1 
ATOM   1220 C CD1 . ILE B 2 51  ? 232.193 176.579 142.066 1.00 22.14  ? 51  ILE H CD1 1 
ATOM   1221 N N   . GLY B 2 52  ? 231.754 177.577 145.476 1.00 25.22  ? 52  GLY H N   1 
ATOM   1222 C CA  . GLY B 2 52  ? 231.235 178.508 146.455 1.00 25.22  ? 52  GLY H CA  1 
ATOM   1223 C C   . GLY B 2 52  ? 229.735 178.667 146.417 1.00 25.22  ? 52  GLY H C   1 
ATOM   1224 O O   . GLY B 2 52  ? 229.019 177.732 146.061 1.00 25.22  ? 52  GLY H O   1 
ATOM   1225 N N   . SER B 2 53  ? 229.241 179.842 146.792 1.00 28.60  ? 53  SER H N   1 
ATOM   1226 C CA  . SER B 2 53  ? 227.804 180.095 146.795 1.00 28.60  ? 53  SER H CA  1 
ATOM   1227 C C   . SER B 2 53  ? 227.399 180.781 145.493 1.00 28.60  ? 53  SER H C   1 
ATOM   1228 O O   . SER B 2 53  ? 227.029 181.951 145.451 1.00 28.60  ? 53  SER H O   1 
ATOM   1229 C CB  . SER B 2 53  ? 227.409 180.922 148.007 1.00 28.60  ? 53  SER H CB  1 
ATOM   1230 O OG  . SER B 2 53  ? 226.004 180.939 148.161 1.00 28.60  ? 53  SER H OG  1 
ATOM   1231 N N   . GLY B 2 54  ? 227.474 180.015 144.413 1.00 33.30  ? 54  GLY H N   1 
ATOM   1232 C CA  . GLY B 2 54  ? 226.939 180.480 143.151 1.00 33.30  ? 54  GLY H CA  1 
ATOM   1233 C C   . GLY B 2 54  ? 227.968 180.675 142.063 1.00 33.30  ? 54  GLY H C   1 
ATOM   1234 O O   . GLY B 2 54  ? 227.824 181.563 141.222 1.00 33.30  ? 54  GLY H O   1 
ATOM   1235 N N   . GLY B 2 55  ? 228.998 179.851 142.051 1.00 27.84  ? 55  GLY H N   1 
ATOM   1236 C CA  . GLY B 2 55  ? 230.099 180.086 141.154 1.00 27.84  ? 55  GLY H CA  1 
ATOM   1237 C C   . GLY B 2 55  ? 230.998 181.171 141.708 1.00 27.84  ? 55  GLY H C   1 
ATOM   1238 O O   . GLY B 2 55  ? 230.924 181.539 142.878 1.00 27.84  ? 55  GLY H O   1 
ATOM   1239 N N   . PHE B 2 56  ? 231.868 181.674 140.838 1.00 31.04  ? 56  PHE H N   1 
ATOM   1240 C CA  . PHE B 2 56  ? 232.891 182.672 141.166 1.00 31.04  ? 56  PHE H CA  1 
ATOM   1241 C C   . PHE B 2 56  ? 233.467 182.471 142.565 1.00 31.04  ? 56  PHE H C   1 
ATOM   1242 O O   . PHE B 2 56  ? 233.607 183.406 143.351 1.00 31.04  ? 56  PHE H O   1 
ATOM   1243 C CB  . PHE B 2 56  ? 232.388 184.115 140.976 1.00 31.04  ? 56  PHE H CB  1 
ATOM   1244 C CG  . PHE B 2 56  ? 231.038 184.425 141.589 1.00 31.04  ? 56  PHE H CG  1 
ATOM   1245 C CD1 . PHE B 2 56  ? 230.837 184.388 142.953 1.00 31.04  ? 56  PHE H CD1 1 
ATOM   1246 C CD2 . PHE B 2 56  ? 229.997 184.860 140.789 1.00 31.04  ? 56  PHE H CD2 1 
ATOM   1247 C CE1 . PHE B 2 56  ? 229.607 184.697 143.494 1.00 31.04  ? 56  PHE H CE1 1 
ATOM   1248 C CE2 . PHE B 2 56  ? 228.770 185.180 141.331 1.00 31.04  ? 56  PHE H CE2 1 
ATOM   1249 C CZ  . PHE B 2 56  ? 228.578 185.098 142.682 1.00 31.04  ? 56  PHE H CZ  1 
ATOM   1250 N N   . ALA B 2 57  ? 233.786 181.225 142.888 1.00 27.79  ? 57  ALA H N   1 
ATOM   1251 C CA  . ALA B 2 57  ? 234.572 180.976 144.090 1.00 27.79  ? 57  ALA H CA  1 
ATOM   1252 C C   . ALA B 2 57  ? 235.517 179.790 143.955 1.00 27.79  ? 57  ALA H C   1 
ATOM   1253 O O   . ALA B 2 57  ? 236.070 179.360 144.972 1.00 27.79  ? 57  ALA H O   1 
ATOM   1254 C CB  . ALA B 2 57  ? 233.657 180.774 145.289 1.00 27.79  ? 57  ALA H CB  1 
ATOM   1255 N N   . THR B 2 58  ? 235.729 179.255 142.754 1.00 26.40  ? 58  THR H N   1 
ATOM   1256 C CA  . THR B 2 58  ? 236.410 177.978 142.585 1.00 26.40  ? 58  THR H CA  1 
ATOM   1257 C C   . THR B 2 58  ? 237.804 177.984 143.196 1.00 26.40  ? 58  THR H C   1 
ATOM   1258 O O   . THR B 2 58  ? 238.561 178.944 143.046 1.00 26.40  ? 58  THR H O   1 
ATOM   1259 C CB  . THR B 2 58  ? 236.524 177.648 141.104 1.00 26.40  ? 58  THR H CB  1 
ATOM   1260 O OG1 . THR B 2 58  ? 237.185 178.727 140.438 1.00 26.40  ? 58  THR H OG1 1 
ATOM   1261 C CG2 . THR B 2 58  ? 235.165 177.479 140.497 1.00 26.40  ? 58  THR H CG2 1 
ATOM   1262 N N   . TYR B 2 59  ? 238.142 176.894 143.878 1.00 26.18  ? 59  TYR H N   1 
ATOM   1263 C CA  . TYR B 2 59  ? 239.489 176.629 144.360 1.00 26.18  ? 59  TYR H CA  1 
ATOM   1264 C C   . TYR B 2 59  ? 239.863 175.215 143.952 1.00 26.18  ? 59  TYR H C   1 
ATOM   1265 O O   . TYR B 2 59  ? 239.028 174.462 143.456 1.00 26.18  ? 59  TYR H O   1 
ATOM   1266 C CB  . TYR B 2 59  ? 239.586 176.807 145.875 1.00 26.18  ? 59  TYR H CB  1 
ATOM   1267 C CG  . TYR B 2 59  ? 239.795 178.239 146.288 1.00 26.18  ? 59  TYR H CG  1 
ATOM   1268 C CD1 . TYR B 2 59  ? 241.034 178.839 146.163 1.00 26.18  ? 59  TYR H CD1 1 
ATOM   1269 C CD2 . TYR B 2 59  ? 238.752 178.994 146.784 1.00 26.18  ? 59  TYR H CD2 1 
ATOM   1270 C CE1 . TYR B 2 59  ? 241.228 180.143 146.530 1.00 26.18  ? 59  TYR H CE1 1 
ATOM   1271 C CE2 . TYR B 2 59  ? 238.937 180.299 147.150 1.00 26.18  ? 59  TYR H CE2 1 
ATOM   1272 C CZ  . TYR B 2 59  ? 240.176 180.868 147.022 1.00 26.18  ? 59  TYR H CZ  1 
ATOM   1273 O OH  . TYR B 2 59  ? 240.370 182.172 147.388 1.00 26.18  ? 59  TYR H OH  1 
ATOM   1274 N N   . TYR B 2 60  ? 241.123 174.840 144.152 1.00 31.78  ? 60  TYR H N   1 
ATOM   1275 C CA  . TYR B 2 60  ? 241.565 173.530 143.697 1.00 31.78  ? 60  TYR H CA  1 
ATOM   1276 C C   . TYR B 2 60  ? 242.731 173.040 144.536 1.00 31.78  ? 60  TYR H C   1 
ATOM   1277 O O   . TYR B 2 60  ? 243.376 173.808 145.248 1.00 31.78  ? 60  TYR H O   1 
ATOM   1278 C CB  . TYR B 2 60  ? 241.981 173.553 142.227 1.00 31.78  ? 60  TYR H CB  1 
ATOM   1279 C CG  . TYR B 2 60  ? 240.831 173.599 141.261 1.00 31.78  ? 60  TYR H CG  1 
ATOM   1280 C CD1 . TYR B 2 60  ? 239.865 172.618 141.263 1.00 31.78  ? 60  TYR H CD1 1 
ATOM   1281 C CD2 . TYR B 2 60  ? 240.719 174.625 140.346 1.00 31.78  ? 60  TYR H CD2 1 
ATOM   1282 C CE1 . TYR B 2 60  ? 238.822 172.662 140.390 1.00 31.78  ? 60  TYR H CE1 1 
ATOM   1283 C CE2 . TYR B 2 60  ? 239.682 174.672 139.469 1.00 31.78  ? 60  TYR H CE2 1 
ATOM   1284 C CZ  . TYR B 2 60  ? 238.735 173.690 139.497 1.00 31.78  ? 60  TYR H CZ  1 
ATOM   1285 O OH  . TYR B 2 60  ? 237.689 173.734 138.618 1.00 31.78  ? 60  TYR H OH  1 
ATOM   1286 N N   . GLY B 2 61  ? 243.004 171.742 144.423 1.00 41.06  ? 61  GLY H N   1 
ATOM   1287 C CA  . GLY B 2 61  ? 244.120 171.130 145.106 1.00 41.06  ? 61  GLY H CA  1 
ATOM   1288 C C   . GLY B 2 61  ? 245.431 171.363 144.389 1.00 41.06  ? 61  GLY H C   1 
ATOM   1289 O O   . GLY B 2 61  ? 245.495 171.948 143.310 1.00 41.06  ? 61  GLY H O   1 
ATOM   1290 N N   . ASP B 2 62  ? 246.509 170.894 145.017 1.00 48.36  ? 62  ASP H N   1 
ATOM   1291 C CA  . ASP B 2 62  ? 247.839 171.130 144.467 1.00 48.36  ? 62  ASP H CA  1 
ATOM   1292 C C   . ASP B 2 62  ? 248.117 170.252 143.255 1.00 48.36  ? 62  ASP H C   1 
ATOM   1293 O O   . ASP B 2 62  ? 248.676 170.722 142.260 1.00 48.36  ? 62  ASP H O   1 
ATOM   1294 C CB  . ASP B 2 62  ? 248.904 170.901 145.537 1.00 48.36  ? 62  ASP H CB  1 
ATOM   1295 C CG  . ASP B 2 62  ? 248.874 171.952 146.626 1.00 48.36  ? 62  ASP H CG  1 
ATOM   1296 O OD1 . ASP B 2 62  ? 248.476 173.099 146.334 1.00 48.36  ? 62  ASP H OD1 1 
ATOM   1297 O OD2 . ASP B 2 62  ? 249.254 171.633 147.773 1.00 48.36  ? 62  ASP H OD2 1 
ATOM   1298 N N   . SER B 2 63  ? 247.739 168.980 143.316 1.00 51.85  ? 63  SER H N   1 
ATOM   1299 C CA  . SER B 2 63  ? 248.124 168.014 142.296 1.00 51.85  ? 63  SER H CA  1 
ATOM   1300 C C   . SER B 2 63  ? 247.158 167.954 141.122 1.00 51.85  ? 63  SER H C   1 
ATOM   1301 O O   . SER B 2 63  ? 247.399 167.192 140.182 1.00 51.85  ? 63  SER H O   1 
ATOM   1302 C CB  . SER B 2 63  ? 248.246 166.623 142.916 1.00 51.85  ? 63  SER H CB  1 
ATOM   1303 O OG  . SER B 2 63  ? 249.040 166.665 144.085 1.00 51.85  ? 63  SER H OG  1 
ATOM   1304 N N   . VAL B 2 64  ? 246.068 168.713 141.156 1.00 48.52  ? 64  VAL H N   1 
ATOM   1305 C CA  . VAL B 2 64  ? 245.060 168.665 140.106 1.00 48.52  ? 64  VAL H CA  1 
ATOM   1306 C C   . VAL B 2 64  ? 244.745 170.071 139.618 1.00 48.52  ? 64  VAL H C   1 
ATOM   1307 O O   . VAL B 2 64  ? 243.619 170.355 139.199 1.00 48.52  ? 64  VAL H O   1 
ATOM   1308 C CB  . VAL B 2 64  ? 243.792 167.962 140.610 1.00 48.52  ? 64  VAL H CB  1 
ATOM   1309 C CG1 . VAL B 2 64  ? 244.109 166.530 140.964 1.00 48.52  ? 64  VAL H CG1 1 
ATOM   1310 C CG2 . VAL B 2 64  ? 243.248 168.687 141.820 1.00 48.52  ? 64  VAL H CG2 1 
ATOM   1311 N N   . LYS B 2 65  ? 245.739 170.959 139.667 1.00 48.55  ? 65  LYS H N   1 
ATOM   1312 C CA  . LYS B 2 65  ? 245.468 172.387 139.541 1.00 48.55  ? 65  LYS H CA  1 
ATOM   1313 C C   . LYS B 2 65  ? 244.853 172.741 138.193 1.00 48.55  ? 65  LYS H C   1 
ATOM   1314 O O   . LYS B 2 65  ? 243.909 173.534 138.126 1.00 48.55  ? 65  LYS H O   1 
ATOM   1315 C CB  . LYS B 2 65  ? 246.753 173.178 139.766 1.00 48.55  ? 65  LYS H CB  1 
ATOM   1316 C CG  . LYS B 2 65  ? 246.531 174.651 140.040 1.00 48.55  ? 65  LYS H CG  1 
ATOM   1317 C CD  . LYS B 2 65  ? 245.787 174.865 141.338 1.00 48.55  ? 65  LYS H CD  1 
ATOM   1318 C CE  . LYS B 2 65  ? 246.076 176.240 141.899 1.00 48.55  ? 65  LYS H CE  1 
ATOM   1319 N NZ  . LYS B 2 65  ? 247.528 176.553 141.827 1.00 48.55  ? 65  LYS H NZ  1 
ATOM   1320 N N   . GLY B 2 66  ? 245.371 172.175 137.109 1.00 52.46  ? 66  GLY H N   1 
ATOM   1321 C CA  . GLY B 2 66  ? 244.925 172.590 135.794 1.00 52.46  ? 66  GLY H CA  1 
ATOM   1322 C C   . GLY B 2 66  ? 244.049 171.594 135.065 1.00 52.46  ? 66  GLY H C   1 
ATOM   1323 O O   . GLY B 2 66  ? 243.502 171.905 134.005 1.00 52.46  ? 66  GLY H O   1 
ATOM   1324 N N   . ARG B 2 67  ? 243.897 170.395 135.621 1.00 52.61  ? 67  ARG H N   1 
ATOM   1325 C CA  . ARG B 2 67  ? 243.204 169.322 134.926 1.00 52.61  ? 67  ARG H CA  1 
ATOM   1326 C C   . ARG B 2 67  ? 241.731 169.206 135.277 1.00 52.61  ? 67  ARG H C   1 
ATOM   1327 O O   . ARG B 2 67  ? 240.990 168.552 134.539 1.00 52.61  ? 67  ARG H O   1 
ATOM   1328 C CB  . ARG B 2 67  ? 243.875 167.982 135.225 1.00 52.61  ? 67  ARG H CB  1 
ATOM   1329 C CG  . ARG B 2 67  ? 245.319 167.911 134.820 1.00 52.61  ? 67  ARG H CG  1 
ATOM   1330 C CD  . ARG B 2 67  ? 245.814 166.488 134.903 1.00 52.61  ? 67  ARG H CD  1 
ATOM   1331 N NE  . ARG B 2 67  ? 246.196 166.110 136.258 1.00 52.61  ? 67  ARG H NE  1 
ATOM   1332 C CZ  . ARG B 2 67  ? 245.593 165.164 136.968 1.00 52.61  ? 67  ARG H CZ  1 
ATOM   1333 N NH1 . ARG B 2 67  ? 244.570 164.500 136.454 1.00 52.61  ? 67  ARG H NH1 1 
ATOM   1334 N NH2 . ARG B 2 67  ? 246.010 164.883 138.192 1.00 52.61  ? 67  ARG H NH2 1 
ATOM   1335 N N   . PHE B 2 68  ? 241.291 169.803 136.377 1.00 46.33  ? 68  PHE H N   1 
ATOM   1336 C CA  . PHE B 2 68  ? 239.947 169.597 136.897 1.00 46.33  ? 68  PHE H CA  1 
ATOM   1337 C C   . PHE B 2 68  ? 239.153 170.891 136.808 1.00 46.33  ? 68  PHE H C   1 
ATOM   1338 O O   . PHE B 2 68  ? 239.631 171.947 137.231 1.00 46.33  ? 68  PHE H O   1 
ATOM   1339 C CB  . PHE B 2 68  ? 239.994 169.119 138.348 1.00 46.33  ? 68  PHE H CB  1 
ATOM   1340 C CG  . PHE B 2 68  ? 240.335 167.670 138.505 1.00 46.33  ? 68  PHE H CG  1 
ATOM   1341 C CD1 . PHE B 2 68  ? 240.885 166.951 137.467 1.00 46.33  ? 68  PHE H CD1 1 
ATOM   1342 C CD2 . PHE B 2 68  ? 240.103 167.027 139.698 1.00 46.33  ? 68  PHE H CD2 1 
ATOM   1343 C CE1 . PHE B 2 68  ? 241.195 165.621 137.619 1.00 46.33  ? 68  PHE H CE1 1 
ATOM   1344 C CE2 . PHE B 2 68  ? 240.414 165.701 139.849 1.00 46.33  ? 68  PHE H CE2 1 
ATOM   1345 C CZ  . PHE B 2 68  ? 240.962 165.001 138.810 1.00 46.33  ? 68  PHE H CZ  1 
ATOM   1346 N N   . THR B 2 69  ? 237.943 170.809 136.270 1.00 42.58  ? 69  THR H N   1 
ATOM   1347 C CA  . THR B 2 69  ? 237.027 171.938 136.241 1.00 42.58  ? 69  THR H CA  1 
ATOM   1348 C C   . THR B 2 69  ? 235.774 171.570 137.014 1.00 42.58  ? 69  THR H C   1 
ATOM   1349 O O   . THR B 2 69  ? 235.158 170.535 136.744 1.00 42.58  ? 69  THR H O   1 
ATOM   1350 C CB  . THR B 2 69  ? 236.661 172.330 134.814 1.00 42.58  ? 69  THR H CB  1 
ATOM   1351 O OG1 . THR B 2 69  ? 237.858 172.544 134.057 1.00 42.58  ? 69  THR H OG1 1 
ATOM   1352 C CG2 . THR B 2 69  ? 235.834 173.601 134.819 1.00 42.58  ? 69  THR H CG2 1 
ATOM   1353 N N   . VAL B 2 70  ? 235.396 172.414 137.968 1.00 34.86  ? 70  VAL H N   1 
ATOM   1354 C CA  . VAL B 2 70  ? 234.221 172.189 138.799 1.00 34.86  ? 70  VAL H CA  1 
ATOM   1355 C C   . VAL B 2 70  ? 233.227 173.310 138.545 1.00 34.86  ? 70  VAL H C   1 
ATOM   1356 O O   . VAL B 2 70  ? 233.607 174.483 138.473 1.00 34.86  ? 70  VAL H O   1 
ATOM   1357 C CB  . VAL B 2 70  ? 234.591 172.094 140.289 1.00 34.86  ? 70  VAL H CB  1 
ATOM   1358 C CG1 . VAL B 2 70  ? 235.304 173.334 140.731 1.00 34.86  ? 70  VAL H CG1 1 
ATOM   1359 C CG2 . VAL B 2 70  ? 233.351 171.886 141.122 1.00 34.86  ? 70  VAL H CG2 1 
ATOM   1360 N N   . SER B 2 71  ? 231.961 172.945 138.373 1.00 40.78  ? 71  SER H N   1 
ATOM   1361 C CA  . SER B 2 71  ? 230.906 173.924 138.174 1.00 40.78  ? 71  SER H CA  1 
ATOM   1362 C C   . SER B 2 71  ? 229.593 173.310 138.620 1.00 40.78  ? 71  SER H C   1 
ATOM   1363 O O   . SER B 2 71  ? 229.430 172.089 138.603 1.00 40.78  ? 71  SER H O   1 
ATOM   1364 C CB  . SER B 2 71  ? 230.816 174.369 136.716 1.00 40.78  ? 71  SER H CB  1 
ATOM   1365 O OG  . SER B 2 71  ? 230.514 173.271 135.877 1.00 40.78  ? 71  SER H OG  1 
ATOM   1366 N N   . ARG B 2 72  ? 228.656 174.163 139.015 1.00 40.57  ? 72  ARG H N   1 
ATOM   1367 C CA  . ARG B 2 72  ? 227.396 173.709 139.573 1.00 40.57  ? 72  ARG H CA  1 
ATOM   1368 C C   . ARG B 2 72  ? 226.237 174.446 138.927 1.00 40.57  ? 72  ARG H C   1 
ATOM   1369 O O   . ARG B 2 72  ? 226.352 175.616 138.557 1.00 40.57  ? 72  ARG H O   1 
ATOM   1370 C CB  . ARG B 2 72  ? 227.353 173.913 141.083 1.00 40.57  ? 72  ARG H CB  1 
ATOM   1371 C CG  . ARG B 2 72  ? 227.714 175.309 141.519 1.00 40.57  ? 72  ARG H CG  1 
ATOM   1372 C CD  . ARG B 2 72  ? 227.810 175.391 143.023 1.00 40.57  ? 72  ARG H CD  1 
ATOM   1373 N NE  . ARG B 2 72  ? 226.514 175.560 143.658 1.00 40.57  ? 72  ARG H NE  1 
ATOM   1374 C CZ  . ARG B 2 72  ? 226.340 175.632 144.969 1.00 40.57  ? 72  ARG H CZ  1 
ATOM   1375 N NH1 . ARG B 2 72  ? 227.373 175.547 145.782 1.00 40.57  ? 72  ARG H NH1 1 
ATOM   1376 N NH2 . ARG B 2 72  ? 225.132 175.793 145.468 1.00 40.57  ? 72  ARG H NH2 1 
ATOM   1377 N N   . ASP B 2 73  ? 225.114 173.745 138.802 1.00 64.25  ? 73  ASP H N   1 
ATOM   1378 C CA  . ASP B 2 73  ? 223.873 174.308 138.278 1.00 64.25  ? 73  ASP H CA  1 
ATOM   1379 C C   . ASP B 2 73  ? 222.842 174.259 139.399 1.00 64.25  ? 73  ASP H C   1 
ATOM   1380 O O   . ASP B 2 73  ? 222.230 173.216 139.644 1.00 64.25  ? 73  ASP H O   1 
ATOM   1381 C CB  . ASP B 2 73  ? 223.402 173.548 137.047 1.00 64.25  ? 73  ASP H CB  1 
ATOM   1382 C CG  . ASP B 2 73  ? 222.369 174.314 136.260 1.00 64.25  ? 73  ASP H CG  1 
ATOM   1383 O OD1 . ASP B 2 73  ? 222.360 175.558 136.351 1.00 64.25  ? 73  ASP H OD1 1 
ATOM   1384 O OD2 . ASP B 2 73  ? 221.576 173.676 135.539 1.00 64.25  ? 73  ASP H OD2 1 
ATOM   1385 N N   . ASP B 2 74  ? 222.651 175.397 140.067 1.00 66.62  ? 74  ASP H N   1 
ATOM   1386 C CA  . ASP B 2 74  ? 221.853 175.430 141.288 1.00 66.62  ? 74  ASP H CA  1 
ATOM   1387 C C   . ASP B 2 74  ? 220.399 175.069 141.015 1.00 66.62  ? 74  ASP H C   1 
ATOM   1388 O O   . ASP B 2 74  ? 219.754 174.400 141.830 1.00 66.62  ? 74  ASP H O   1 
ATOM   1389 C CB  . ASP B 2 74  ? 221.945 176.816 141.924 1.00 66.62  ? 74  ASP H CB  1 
ATOM   1390 C CG  . ASP B 2 74  ? 223.325 177.117 142.477 1.00 66.62  ? 74  ASP H CG  1 
ATOM   1391 O OD1 . ASP B 2 74  ? 224.032 176.172 142.882 1.00 66.62  ? 74  ASP H OD1 1 
ATOM   1392 O OD2 . ASP B 2 74  ? 223.708 178.303 142.503 1.00 66.62  ? 74  ASP H OD2 1 
ATOM   1393 N N   . ALA B 2 75  ? 219.865 175.506 139.872 1.00 75.97  ? 75  ALA H N   1 
ATOM   1394 C CA  . ALA B 2 75  ? 218.443 175.329 139.592 1.00 75.97  ? 75  ALA H CA  1 
ATOM   1395 C C   . ALA B 2 75  ? 218.074 173.856 139.464 1.00 75.97  ? 75  ALA H C   1 
ATOM   1396 O O   . ALA B 2 75  ? 216.976 173.448 139.856 1.00 75.97  ? 75  ALA H O   1 
ATOM   1397 C CB  . ALA B 2 75  ? 218.062 176.090 138.324 1.00 75.97  ? 75  ALA H CB  1 
ATOM   1398 N N   . GLU B 2 76  ? 218.971 173.045 138.913 1.00 77.88  ? 76  GLU H N   1 
ATOM   1399 C CA  . GLU B 2 76  ? 218.693 171.629 138.725 1.00 77.88  ? 76  GLU H CA  1 
ATOM   1400 C C   . GLU B 2 76  ? 218.998 170.791 139.959 1.00 77.88  ? 76  GLU H C   1 
ATOM   1401 O O   . GLU B 2 76  ? 218.818 169.571 139.907 1.00 77.88  ? 76  GLU H O   1 
ATOM   1402 C CB  . GLU B 2 76  ? 219.493 171.088 137.539 1.00 77.88  ? 76  GLU H CB  1 
ATOM   1403 C CG  . GLU B 2 76  ? 219.180 171.756 136.220 1.00 77.88  ? 76  GLU H CG  1 
ATOM   1404 C CD  . GLU B 2 76  ? 217.841 171.337 135.662 1.00 77.88  ? 76  GLU H CD  1 
ATOM   1405 O OE1 . GLU B 2 76  ? 217.523 170.132 135.726 1.00 77.88  ? 76  GLU H OE1 1 
ATOM   1406 O OE2 . GLU B 2 76  ? 217.107 172.210 135.157 1.00 77.88  ? 76  GLU H OE2 1 
ATOM   1407 N N   . ASN B 2 77  ? 219.449 171.407 141.053 1.00 70.30  ? 77  ASN H N   1 
ATOM   1408 C CA  . ASN B 2 77  ? 219.889 170.675 142.240 1.00 70.30  ? 77  ASN H CA  1 
ATOM   1409 C C   . ASN B 2 77  ? 220.921 169.618 141.867 1.00 70.30  ? 77  ASN H C   1 
ATOM   1410 O O   . ASN B 2 77  ? 220.858 168.472 142.313 1.00 70.30  ? 77  ASN H O   1 
ATOM   1411 C CB  . ASN B 2 77  ? 218.710 170.044 142.979 1.00 70.30  ? 77  ASN H CB  1 
ATOM   1412 C CG  . ASN B 2 77  ? 217.746 171.074 143.525 1.00 70.30  ? 77  ASN H CG  1 
ATOM   1413 O OD1 . ASN B 2 77  ? 218.092 171.855 144.409 1.00 70.30  ? 77  ASN H OD1 1 
ATOM   1414 N ND2 . ASN B 2 77  ? 216.534 171.093 142.991 1.00 70.30  ? 77  ASN H ND2 1 
ATOM   1415 N N   . SER B 2 78  ? 221.874 170.007 141.028 1.00 63.25  ? 78  SER H N   1 
ATOM   1416 C CA  . SER B 2 78  ? 222.877 169.095 140.511 1.00 63.25  ? 78  SER H CA  1 
ATOM   1417 C C   . SER B 2 78  ? 224.257 169.719 140.647 1.00 63.25  ? 78  SER H C   1 
ATOM   1418 O O   . SER B 2 78  ? 224.398 170.918 140.894 1.00 63.25  ? 78  SER H O   1 
ATOM   1419 C CB  . SER B 2 78  ? 222.602 168.741 139.050 1.00 63.25  ? 78  SER H CB  1 
ATOM   1420 O OG  . SER B 2 78  ? 223.582 167.850 138.556 1.00 63.25  ? 78  SER H OG  1 
ATOM   1421 N N   . LEU B 2 79  ? 225.282 168.884 140.494 1.00 50.65  ? 79  LEU H N   1 
ATOM   1422 C CA  . LEU B 2 79  ? 226.664 169.328 140.579 1.00 50.65  ? 79  LEU H CA  1 
ATOM   1423 C C   . LEU B 2 79  ? 227.525 168.476 139.660 1.00 50.65  ? 79  LEU H C   1 
ATOM   1424 O O   . LEU B 2 79  ? 227.297 167.275 139.514 1.00 50.65  ? 79  LEU H O   1 
ATOM   1425 C CB  . LEU B 2 79  ? 227.186 169.244 142.007 1.00 50.65  ? 79  LEU H CB  1 
ATOM   1426 C CG  . LEU B 2 79  ? 228.453 170.036 142.290 1.00 50.65  ? 79  LEU H CG  1 
ATOM   1427 C CD1 . LEU B 2 79  ? 228.436 170.472 143.716 1.00 50.65  ? 79  LEU H CD1 1 
ATOM   1428 C CD2 . LEU B 2 79  ? 229.674 169.207 142.031 1.00 50.65  ? 79  LEU H CD2 1 
ATOM   1429 N N   . TYR B 2 80  ? 228.530 169.103 139.058 1.00 47.39  ? 80  TYR H N   1 
ATOM   1430 C CA  . TYR B 2 80  ? 229.394 168.448 138.090 1.00 47.39  ? 80  TYR H CA  1 
ATOM   1431 C C   . TYR B 2 80  ? 230.852 168.701 138.429 1.00 47.39  ? 80  TYR H C   1 
ATOM   1432 O O   . TYR B 2 80  ? 231.212 169.762 138.939 1.00 47.39  ? 80  TYR H O   1 
ATOM   1433 C CB  . TYR B 2 80  ? 229.132 168.950 136.665 1.00 47.39  ? 80  TYR H CB  1 
ATOM   1434 C CG  . TYR B 2 80  ? 227.681 169.023 136.273 1.00 47.39  ? 80  TYR H CG  1 
ATOM   1435 C CD1 . TYR B 2 80  ? 226.829 167.962 136.504 1.00 47.39  ? 80  TYR H CD1 1 
ATOM   1436 C CD2 . TYR B 2 80  ? 227.159 170.166 135.697 1.00 47.39  ? 80  TYR H CD2 1 
ATOM   1437 C CE1 . TYR B 2 80  ? 225.509 168.026 136.151 1.00 47.39  ? 80  TYR H CE1 1 
ATOM   1438 C CE2 . TYR B 2 80  ? 225.839 170.241 135.342 1.00 47.39  ? 80  TYR H CE2 1 
ATOM   1439 C CZ  . TYR B 2 80  ? 225.016 169.168 135.573 1.00 47.39  ? 80  TYR H CZ  1 
ATOM   1440 O OH  . TYR B 2 80  ? 223.690 169.235 135.221 1.00 47.39  ? 80  TYR H OH  1 
ATOM   1441 N N   . LEU B 2 81  ? 231.689 167.714 138.130 1.00 40.10  ? 81  LEU H N   1 
ATOM   1442 C CA  . LEU B 2 81  ? 233.136 167.860 138.159 1.00 40.10  ? 81  LEU H CA  1 
ATOM   1443 C C   . LEU B 2 81  ? 233.668 167.372 136.826 1.00 40.10  ? 81  LEU H C   1 
ATOM   1444 O O   . LEU B 2 81  ? 233.309 166.278 136.384 1.00 40.10  ? 81  LEU H O   1 
ATOM   1445 C CB  . LEU B 2 81  ? 233.765 167.065 139.306 1.00 40.10  ? 81  LEU H CB  1 
ATOM   1446 C CG  . LEU B 2 81  ? 235.285 167.120 139.468 1.00 40.10  ? 81  LEU H CG  1 
ATOM   1447 C CD1 . LEU B 2 81  ? 235.721 168.531 139.720 1.00 40.10  ? 81  LEU H CD1 1 
ATOM   1448 C CD2 . LEU B 2 81  ? 235.732 166.243 140.610 1.00 40.10  ? 81  LEU H CD2 1 
ATOM   1449 N N   . GLN B 2 82  ? 234.505 168.179 136.181 1.00 45.23  ? 82  GLN H N   1 
ATOM   1450 C CA  . GLN B 2 82  ? 235.042 167.860 134.864 1.00 45.23  ? 82  GLN H CA  1 
ATOM   1451 C C   . GLN B 2 82  ? 236.520 167.533 134.979 1.00 45.23  ? 82  GLN H C   1 
ATOM   1452 O O   . GLN B 2 82  ? 237.273 168.267 135.624 1.00 45.23  ? 82  GLN H O   1 
ATOM   1453 C CB  . GLN B 2 82  ? 234.832 169.013 133.885 1.00 45.23  ? 82  GLN H CB  1 
ATOM   1454 C CG  . GLN B 2 82  ? 235.478 168.799 132.529 1.00 45.23  ? 82  GLN H CG  1 
ATOM   1455 C CD  . GLN B 2 82  ? 234.685 167.870 131.633 1.00 45.23  ? 82  GLN H CD  1 
ATOM   1456 O OE1 . GLN B 2 82  ? 234.298 166.776 132.036 1.00 45.23  ? 82  GLN H OE1 1 
ATOM   1457 N NE2 . GLN B 2 82  ? 234.441 168.304 130.406 1.00 45.23  ? 82  GLN H NE2 1 
ATOM   1458 N N   . MET B 2 83  ? 236.930 166.442 134.346 1.00 53.00  ? 83  MET H N   1 
ATOM   1459 C CA  . MET B 2 83  ? 238.281 165.916 134.466 1.00 53.00  ? 83  MET H CA  1 
ATOM   1460 C C   . MET B 2 83  ? 238.907 165.861 133.082 1.00 53.00  ? 83  MET H C   1 
ATOM   1461 O O   . MET B 2 83  ? 238.341 165.255 132.168 1.00 53.00  ? 83  MET H O   1 
ATOM   1462 C CB  . MET B 2 83  ? 238.246 164.532 135.109 1.00 53.00  ? 83  MET H CB  1 
ATOM   1463 C CG  . MET B 2 83  ? 237.398 164.488 136.368 1.00 53.00  ? 83  MET H CG  1 
ATOM   1464 S SD  . MET B 2 83  ? 237.435 162.918 137.244 1.00 53.00  ? 83  MET H SD  1 
ATOM   1465 C CE  . MET B 2 83  ? 239.182 162.589 137.296 1.00 53.00  ? 83  MET H CE  1 
ATOM   1466 N N   . ASN B 2 84  ? 240.070 166.484 132.926 1.00 56.04  ? 84  ASN H N   1 
ATOM   1467 C CA  . ASN B 2 84  ? 240.745 166.543 131.639 1.00 56.04  ? 84  ASN H CA  1 
ATOM   1468 C C   . ASN B 2 84  ? 242.176 166.049 131.775 1.00 56.04  ? 84  ASN H C   1 
ATOM   1469 O O   . ASN B 2 84  ? 242.791 166.169 132.837 1.00 56.04  ? 84  ASN H O   1 
ATOM   1470 C CB  . ASN B 2 84  ? 240.760 167.963 131.074 1.00 56.04  ? 84  ASN H CB  1 
ATOM   1471 C CG  . ASN B 2 84  ? 239.414 168.395 130.555 1.00 56.04  ? 84  ASN H CG  1 
ATOM   1472 O OD1 . ASN B 2 84  ? 238.518 168.727 131.326 1.00 56.04  ? 84  ASN H OD1 1 
ATOM   1473 N ND2 . ASN B 2 84  ? 239.261 168.398 129.238 1.00 56.04  ? 84  ASN H ND2 1 
ATOM   1474 N N   . SER B 2 85  ? 242.699 165.501 130.682 1.00 62.55  ? 85  SER H N   1 
ATOM   1475 C CA  . SER B 2 85  ? 244.096 165.086 130.583 1.00 62.55  ? 85  SER H CA  1 
ATOM   1476 C C   . SER B 2 85  ? 244.475 164.163 131.739 1.00 62.55  ? 85  SER H C   1 
ATOM   1477 O O   . SER B 2 85  ? 245.445 164.384 132.463 1.00 62.55  ? 85  SER H O   1 
ATOM   1478 C CB  . SER B 2 85  ? 245.016 166.306 130.530 1.00 62.55  ? 85  SER H CB  1 
ATOM   1479 O OG  . SER B 2 85  ? 244.787 167.061 129.354 1.00 62.55  ? 85  SER H OG  1 
ATOM   1480 N N   . LEU B 2 86  ? 243.681 163.110 131.896 1.00 66.08  ? 86  LEU H N   1 
ATOM   1481 C CA  . LEU B 2 86  ? 243.831 162.226 133.036 1.00 66.08  ? 86  LEU H CA  1 
ATOM   1482 C C   . LEU B 2 86  ? 245.143 161.451 132.968 1.00 66.08  ? 86  LEU H C   1 
ATOM   1483 O O   . LEU B 2 86  ? 245.687 161.181 131.895 1.00 66.08  ? 86  LEU H O   1 
ATOM   1484 C CB  . LEU B 2 86  ? 242.658 161.253 133.114 1.00 66.08  ? 86  LEU H CB  1 
ATOM   1485 C CG  . LEU B 2 86  ? 241.469 161.777 133.913 1.00 66.08  ? 86  LEU H CG  1 
ATOM   1486 C CD1 . LEU B 2 86  ? 240.486 160.665 134.221 1.00 66.08  ? 86  LEU H CD1 1 
ATOM   1487 C CD2 . LEU B 2 86  ? 241.971 162.424 135.183 1.00 66.08  ? 86  LEU H CD2 1 
ATOM   1488 N N   . ARG B 2 87  ? 245.653 161.104 134.147 1.00 62.80  ? 87  ARG H N   1 
ATOM   1489 C CA  . ARG B 2 87  ? 246.800 160.215 134.263 1.00 62.80  ? 87  ARG H CA  1 
ATOM   1490 C C   . ARG B 2 87  ? 246.437 159.019 135.131 1.00 62.80  ? 87  ARG H C   1 
ATOM   1491 O O   . ARG B 2 87  ? 245.266 158.837 135.473 1.00 62.80  ? 87  ARG H O   1 
ATOM   1492 C CB  . ARG B 2 87  ? 248.020 160.955 134.812 1.00 62.80  ? 87  ARG H CB  1 
ATOM   1493 C CG  . ARG B 2 87  ? 247.787 161.689 136.112 1.00 62.80  ? 87  ARG H CG  1 
ATOM   1494 C CD  . ARG B 2 87  ? 248.841 162.773 136.310 1.00 62.80  ? 87  ARG H CD  1 
ATOM   1495 N NE  . ARG B 2 87  ? 248.708 163.908 135.403 1.00 62.80  ? 87  ARG H NE  1 
ATOM   1496 C CZ  . ARG B 2 87  ? 249.085 165.146 135.704 1.00 62.80  ? 87  ARG H CZ  1 
ATOM   1497 N NH1 . ARG B 2 87  ? 249.607 165.410 136.892 1.00 62.80  ? 87  ARG H NH1 1 
ATOM   1498 N NH2 . ARG B 2 87  ? 248.942 166.120 134.819 1.00 62.80  ? 87  ARG H NH2 1 
ATOM   1499 N N   . ALA B 2 88  ? 247.427 158.201 135.490 1.00 66.13  ? 88  ALA H N   1 
ATOM   1500 C CA  . ALA B 2 88  ? 247.167 156.861 136.004 1.00 66.13  ? 88  ALA H CA  1 
ATOM   1501 C C   . ALA B 2 88  ? 247.206 156.739 137.521 1.00 66.13  ? 88  ALA H C   1 
ATOM   1502 O O   . ALA B 2 88  ? 246.592 155.813 138.060 1.00 66.13  ? 88  ALA H O   1 
ATOM   1503 C CB  . ALA B 2 88  ? 248.172 155.867 135.410 1.00 66.13  ? 88  ALA H CB  1 
ATOM   1504 N N   . GLU B 2 89  ? 247.900 157.624 138.229 1.00 71.88  ? 89  GLU H N   1 
ATOM   1505 C CA  . GLU B 2 89  ? 248.059 157.457 139.665 1.00 71.88  ? 89  GLU H CA  1 
ATOM   1506 C C   . GLU B 2 89  ? 246.980 158.173 140.462 1.00 71.88  ? 89  GLU H C   1 
ATOM   1507 O O   . GLU B 2 89  ? 247.054 158.204 141.693 1.00 71.88  ? 89  GLU H O   1 
ATOM   1508 C CB  . GLU B 2 89  ? 249.439 157.936 140.120 1.00 71.88  ? 89  GLU H CB  1 
ATOM   1509 C CG  . GLU B 2 89  ? 249.639 159.439 140.121 1.00 71.88  ? 89  GLU H CG  1 
ATOM   1510 C CD  . GLU B 2 89  ? 249.816 160.028 138.740 1.00 71.88  ? 89  GLU H CD  1 
ATOM   1511 O OE1 . GLU B 2 89  ? 249.992 161.259 138.655 1.00 71.88  ? 89  GLU H OE1 1 
ATOM   1512 O OE2 . GLU B 2 89  ? 249.773 159.274 137.745 1.00 71.88  ? 89  GLU H OE2 1 
ATOM   1513 N N   . ASP B 2 90  ? 245.985 158.756 139.796 1.00 60.44  ? 90  ASP H N   1 
ATOM   1514 C CA  . ASP B 2 90  ? 244.869 159.387 140.485 1.00 60.44  ? 90  ASP H CA  1 
ATOM   1515 C C   . ASP B 2 90  ? 243.634 158.498 140.511 1.00 60.44  ? 90  ASP H C   1 
ATOM   1516 O O   . ASP B 2 90  ? 242.508 159.002 140.486 1.00 60.44  ? 90  ASP H O   1 
ATOM   1517 C CB  . ASP B 2 90  ? 244.537 160.738 139.854 1.00 60.44  ? 90  ASP H CB  1 
ATOM   1518 C CG  . ASP B 2 90  ? 244.084 160.617 138.420 1.00 60.44  ? 90  ASP H CG  1 
ATOM   1519 O OD1 . ASP B 2 90  ? 244.059 159.492 137.887 1.00 60.44  ? 90  ASP H OD1 1 
ATOM   1520 O OD2 . ASP B 2 90  ? 243.752 161.657 137.818 1.00 60.44  ? 90  ASP H OD2 1 
ATOM   1521 N N   . THR B 2 91  ? 243.823 157.181 140.525 1.00 49.81  ? 91  THR H N   1 
ATOM   1522 C CA  . THR B 2 91  ? 242.715 156.269 140.757 1.00 49.81  ? 91  THR H CA  1 
ATOM   1523 C C   . THR B 2 91  ? 242.296 156.361 142.216 1.00 49.81  ? 91  THR H C   1 
ATOM   1524 O O   . THR B 2 91  ? 243.143 156.389 143.112 1.00 49.81  ? 91  THR H O   1 
ATOM   1525 C CB  . THR B 2 91  ? 243.098 154.839 140.385 1.00 49.81  ? 91  THR H CB  1 
ATOM   1526 O OG1 . THR B 2 91  ? 241.967 153.980 140.560 1.00 49.81  ? 91  THR H OG1 1 
ATOM   1527 C CG2 . THR B 2 91  ? 244.259 154.339 141.219 1.00 49.81  ? 91  THR H CG2 1 
ATOM   1528 N N   . ALA B 2 92  ? 241.000 156.445 142.454 1.00 33.61  ? 92  ALA H N   1 
ATOM   1529 C CA  . ALA B 2 92  ? 240.505 156.748 143.789 1.00 33.61  ? 92  ALA H CA  1 
ATOM   1530 C C   . ALA B 2 92  ? 239.014 156.459 143.819 1.00 33.61  ? 92  ALA H C   1 
ATOM   1531 O O   . ALA B 2 92  ? 238.468 155.845 142.897 1.00 33.61  ? 92  ALA H O   1 
ATOM   1532 C CB  . ALA B 2 92  ? 240.813 158.193 144.167 1.00 33.61  ? 92  ALA H CB  1 
ATOM   1533 N N   . VAL B 2 93  ? 238.355 156.885 144.889 1.00 28.77  ? 93  VAL H N   1 
ATOM   1534 C CA  . VAL B 2 93  ? 236.913 156.725 145.050 1.00 28.77  ? 93  VAL H CA  1 
ATOM   1535 C C   . VAL B 2 93  ? 236.373 158.101 145.425 1.00 28.77  ? 93  VAL H C   1 
ATOM   1536 O O   . VAL B 2 93  ? 236.309 158.458 146.603 1.00 28.77  ? 93  VAL H O   1 
ATOM   1537 C CB  . VAL B 2 93  ? 236.556 155.686 146.112 1.00 28.77  ? 93  VAL H CB  1 
ATOM   1538 C CG1 . VAL B 2 93  ? 235.093 155.382 146.064 1.00 28.77  ? 93  VAL H CG1 1 
ATOM   1539 C CG2 . VAL B 2 93  ? 237.366 154.433 145.911 1.00 28.77  ? 93  VAL H CG2 1 
ATOM   1540 N N   . TYR B 2 94  ? 235.963 158.875 144.428 1.00 26.97  ? 94  TYR H N   1 
ATOM   1541 C CA  . TYR B 2 94  ? 235.618 160.272 144.645 1.00 26.97  ? 94  TYR H CA  1 
ATOM   1542 C C   . TYR B 2 94  ? 234.278 160.405 145.352 1.00 26.97  ? 94  TYR H C   1 
ATOM   1543 O O   . TYR B 2 94  ? 233.302 159.759 144.970 1.00 26.97  ? 94  TYR H O   1 
ATOM   1544 C CB  . TYR B 2 94  ? 235.581 161.011 143.312 1.00 26.97  ? 94  TYR H CB  1 
ATOM   1545 C CG  . TYR B 2 94  ? 236.923 161.097 142.643 1.00 26.97  ? 94  TYR H CG  1 
ATOM   1546 C CD1 . TYR B 2 94  ? 237.409 160.051 141.893 1.00 26.97  ? 94  TYR H CD1 1 
ATOM   1547 C CD2 . TYR B 2 94  ? 237.707 162.220 142.771 1.00 26.97  ? 94  TYR H CD2 1 
ATOM   1548 C CE1 . TYR B 2 94  ? 238.628 160.123 141.292 1.00 26.97  ? 94  TYR H CE1 1 
ATOM   1549 C CE2 . TYR B 2 94  ? 238.927 162.299 142.171 1.00 26.97  ? 94  TYR H CE2 1 
ATOM   1550 C CZ  . TYR B 2 94  ? 239.383 161.248 141.433 1.00 26.97  ? 94  TYR H CZ  1 
ATOM   1551 O OH  . TYR B 2 94  ? 240.609 161.319 140.825 1.00 26.97  ? 94  TYR H OH  1 
ATOM   1552 N N   . TYR B 2 95  ? 234.232 161.249 146.376 1.00 25.66  ? 95  TYR H N   1 
ATOM   1553 C CA  . TYR B 2 95  ? 233.001 161.608 147.062 1.00 25.66  ? 95  TYR H CA  1 
ATOM   1554 C C   . TYR B 2 95  ? 232.653 163.054 146.745 1.00 25.66  ? 95  TYR H C   1 
ATOM   1555 O O   . TYR B 2 95  ? 233.495 163.819 146.275 1.00 25.66  ? 95  TYR H O   1 
ATOM   1556 C CB  . TYR B 2 95  ? 233.138 161.437 148.578 1.00 25.66  ? 95  TYR H CB  1 
ATOM   1557 C CG  . TYR B 2 95  ? 233.608 160.081 149.029 1.00 25.66  ? 95  TYR H CG  1 
ATOM   1558 C CD1 . TYR B 2 95  ? 232.725 159.031 149.165 1.00 25.66  ? 95  TYR H CD1 1 
ATOM   1559 C CD2 . TYR B 2 95  ? 234.930 159.856 149.330 1.00 25.66  ? 95  TYR H CD2 1 
ATOM   1560 C CE1 . TYR B 2 95  ? 233.151 157.796 149.578 1.00 25.66  ? 95  TYR H CE1 1 
ATOM   1561 C CE2 . TYR B 2 95  ? 235.364 158.627 149.744 1.00 25.66  ? 95  TYR H CE2 1 
ATOM   1562 C CZ  . TYR B 2 95  ? 234.471 157.600 149.867 1.00 25.66  ? 95  TYR H CZ  1 
ATOM   1563 O OH  . TYR B 2 95  ? 234.907 156.367 150.280 1.00 25.66  ? 95  TYR H OH  1 
ATOM   1564 N N   . CYS B 2 96  ? 231.403 163.436 147.002 1.00 32.90  ? 96  CYS H N   1 
ATOM   1565 C CA  . CYS B 2 96  ? 230.996 164.838 146.897 1.00 32.90  ? 96  CYS H CA  1 
ATOM   1566 C C   . CYS B 2 96  ? 230.376 165.240 148.229 1.00 32.90  ? 96  CYS H C   1 
ATOM   1567 O O   . CYS B 2 96  ? 229.219 164.931 148.513 1.00 32.90  ? 96  CYS H O   1 
ATOM   1568 C CB  . CYS B 2 96  ? 230.061 165.087 145.701 1.00 32.90  ? 96  CYS H CB  1 
ATOM   1569 S SG  . CYS B 2 96  ? 228.283 164.709 145.794 1.00 32.90  ? 96  CYS H SG  1 
ATOM   1570 N N   . ALA B 2 97  ? 231.158 165.921 149.053 1.00 28.05  ? 97  ALA H N   1 
ATOM   1571 C CA  . ALA B 2 97  ? 230.738 166.275 150.398 1.00 28.05  ? 97  ALA H CA  1 
ATOM   1572 C C   . ALA B 2 97  ? 229.827 167.492 150.349 1.00 28.05  ? 97  ALA H C   1 
ATOM   1573 O O   . ALA B 2 97  ? 229.364 167.909 149.288 1.00 28.05  ? 97  ALA H O   1 
ATOM   1574 C CB  . ALA B 2 97  ? 231.955 166.524 151.274 1.00 28.05  ? 97  ALA H CB  1 
ATOM   1575 N N   . ARG B 2 98  ? 229.542 168.066 151.510 1.00 33.51  ? 98  ARG H N   1 
ATOM   1576 C CA  . ARG B 2 98  ? 228.855 169.343 151.602 1.00 33.51  ? 98  ARG H CA  1 
ATOM   1577 C C   . ARG B 2 98  ? 229.305 170.016 152.884 1.00 33.51  ? 98  ARG H C   1 
ATOM   1578 O O   . ARG B 2 98  ? 229.515 169.347 153.896 1.00 33.51  ? 98  ARG H O   1 
ATOM   1579 C CB  . ARG B 2 98  ? 227.337 169.180 151.595 1.00 33.51  ? 98  ARG H CB  1 
ATOM   1580 C CG  . ARG B 2 98  ? 226.586 170.493 151.579 1.00 33.51  ? 98  ARG H CG  1 
ATOM   1581 C CD  . ARG B 2 98  ? 225.155 170.326 152.055 1.00 33.51  ? 98  ARG H CD  1 
ATOM   1582 N NE  . ARG B 2 98  ? 225.085 170.029 153.483 1.00 33.51  ? 98  ARG H NE  1 
ATOM   1583 C CZ  . ARG B 2 98  ? 224.056 170.344 154.260 1.00 33.51  ? 98  ARG H CZ  1 
ATOM   1584 N NH1 . ARG B 2 98  ? 224.069 170.039 155.549 1.00 33.51  ? 98  ARG H NH1 1 
ATOM   1585 N NH2 . ARG B 2 98  ? 223.009 170.967 153.745 1.00 33.51  ? 98  ARG H NH2 1 
ATOM   1586 N N   . GLY B 2 99  ? 229.467 171.332 152.840 1.00 35.72  ? 99  GLY H N   1 
ATOM   1587 C CA  . GLY B 2 99  ? 229.984 172.080 153.971 1.00 35.72  ? 99  GLY H CA  1 
ATOM   1588 C C   . GLY B 2 99  ? 228.869 172.780 154.729 1.00 35.72  ? 99  GLY H C   1 
ATOM   1589 O O   . GLY B 2 99  ? 228.002 173.409 154.131 1.00 35.72  ? 99  GLY H O   1 
ATOM   1590 N N   . VAL B 2 100 ? 228.914 172.682 156.053 1.00 36.53  ? 100 VAL H N   1 
ATOM   1591 C CA  . VAL B 2 100 ? 227.930 173.387 156.860 1.00 36.53  ? 100 VAL H CA  1 
ATOM   1592 C C   . VAL B 2 100 ? 228.243 174.872 156.767 1.00 36.53  ? 100 VAL H C   1 
ATOM   1593 O O   . VAL B 2 100 ? 229.146 175.379 157.437 1.00 36.53  ? 100 VAL H O   1 
ATOM   1594 C CB  . VAL B 2 100 ? 227.908 172.880 158.314 1.00 36.53  ? 100 VAL H CB  1 
ATOM   1595 C CG1 . VAL B 2 100 ? 227.365 171.491 158.354 1.00 36.53  ? 100 VAL H CG1 1 
ATOM   1596 C CG2 . VAL B 2 100 ? 229.296 172.845 158.901 1.00 36.53  ? 100 VAL H CG2 1 
ATOM   1597 N N   . THR B 2 101 ? 227.507 175.576 155.910 1.00 41.47  ? 101 THR H N   1 
ATOM   1598 C CA  . THR B 2 101 ? 227.810 176.977 155.651 1.00 41.47  ? 101 THR H CA  1 
ATOM   1599 C C   . THR B 2 101 ? 227.743 177.808 156.925 1.00 41.47  ? 101 THR H C   1 
ATOM   1600 O O   . THR B 2 101 ? 228.664 178.570 157.231 1.00 41.47  ? 101 THR H O   1 
ATOM   1601 C CB  . THR B 2 101 ? 226.844 177.527 154.608 1.00 41.47  ? 101 THR H CB  1 
ATOM   1602 O OG1 . THR B 2 101 ? 226.849 176.671 153.460 1.00 41.47  ? 101 THR H OG1 1 
ATOM   1603 C CG2 . THR B 2 101 ? 227.253 178.927 154.196 1.00 41.47  ? 101 THR H CG2 1 
ATOM   1604 N N   . SER B 2 102 ? 226.663 177.668 157.686 1.00 46.69  ? 102 SER H N   1 
ATOM   1605 C CA  . SER B 2 102 ? 226.481 178.432 158.909 1.00 46.69  ? 102 SER H CA  1 
ATOM   1606 C C   . SER B 2 102 ? 225.993 177.509 160.010 1.00 46.69  ? 102 SER H C   1 
ATOM   1607 O O   . SER B 2 102 ? 225.227 176.578 159.761 1.00 46.69  ? 102 SER H O   1 
ATOM   1608 C CB  . SER B 2 102 ? 225.482 179.576 158.716 1.00 46.69  ? 102 SER H CB  1 
ATOM   1609 O OG  . SER B 2 102 ? 226.000 180.562 157.845 1.00 46.69  ? 102 SER H OG  1 
ATOM   1610 N N   . TYR B 2 103 ? 226.494 177.732 161.222 1.00 55.21  ? 103 TYR H N   1 
ATOM   1611 C CA  . TYR B 2 103 ? 226.019 176.956 162.389 1.00 55.21  ? 103 TYR H CA  1 
ATOM   1612 C C   . TYR B 2 103 ? 225.617 177.925 163.493 1.00 55.21  ? 103 TYR H C   1 
ATOM   1613 O O   . TYR B 2 103 ? 226.479 178.291 164.294 1.00 55.21  ? 103 TYR H O   1 
ATOM   1614 C CB  . TYR B 2 103 ? 227.101 176.038 162.944 1.00 55.21  ? 103 TYR H CB  1 
ATOM   1615 C CG  . TYR B 2 103 ? 226.706 175.333 164.215 1.00 55.21  ? 103 TYR H CG  1 
ATOM   1616 C CD1 . TYR B 2 103 ? 227.494 175.416 165.349 1.00 55.21  ? 103 TYR H CD1 1 
ATOM   1617 C CD2 . TYR B 2 103 ? 225.519 174.627 164.302 1.00 55.21  ? 103 TYR H CD2 1 
ATOM   1618 C CE1 . TYR B 2 103 ? 227.125 174.794 166.528 1.00 55.21  ? 103 TYR H CE1 1 
ATOM   1619 C CE2 . TYR B 2 103 ? 225.135 174.000 165.474 1.00 55.21  ? 103 TYR H CE2 1 
ATOM   1620 C CZ  . TYR B 2 103 ? 225.942 174.083 166.592 1.00 55.21  ? 103 TYR H CZ  1 
ATOM   1621 O OH  . TYR B 2 103 ? 225.571 173.464 167.750 1.00 55.21  ? 103 TYR H OH  1 
ATOM   1622 N N   . SER B 2 104 ? 224.356 178.348 163.527 1.00 64.85  ? 104 SER H N   1 
ATOM   1623 C CA  . SER B 2 104 ? 223.876 179.210 164.635 1.00 64.85  ? 104 SER H CA  1 
ATOM   1624 C C   . SER B 2 104 ? 223.796 178.376 165.913 1.00 64.85  ? 104 SER H C   1 
ATOM   1625 O O   . SER B 2 104 ? 222.850 177.586 166.030 1.00 64.85  ? 104 SER H O   1 
ATOM   1626 C CB  . SER B 2 104 ? 222.557 179.823 164.305 1.00 64.85  ? 104 SER H CB  1 
ATOM   1627 O OG  . SER B 2 104 ? 222.548 180.341 162.984 1.00 64.85  ? 104 SER H OG  1 
ATOM   1628 N N   . ASP B 2 105 ? 224.745 178.549 166.834 1.00 72.80  ? 105 ASP H N   1 
ATOM   1629 C CA  . ASP B 2 105 ? 224.805 177.757 168.094 1.00 72.80  ? 105 ASP H CA  1 
ATOM   1630 C C   . ASP B 2 105 ? 223.663 178.148 169.037 1.00 72.80  ? 105 ASP H C   1 
ATOM   1631 O O   . ASP B 2 105 ? 222.889 179.054 168.686 1.00 72.80  ? 105 ASP H O   1 
ATOM   1632 C CB  . ASP B 2 105 ? 226.179 177.937 168.740 1.00 72.80  ? 105 ASP H CB  1 
ATOM   1633 C CG  . ASP B 2 105 ? 226.488 177.024 169.914 1.00 72.80  ? 105 ASP H CG  1 
ATOM   1634 O OD1 . ASP B 2 105 ? 226.352 177.488 171.062 1.00 72.80  ? 105 ASP H OD1 1 
ATOM   1635 O OD2 . ASP B 2 105 ? 226.853 175.861 169.674 1.00 72.80  ? 105 ASP H OD2 1 
ATOM   1636 N N   . ASN B 2 106 ? 223.570 177.509 170.206 1.00 69.37  ? 106 ASN H N   1 
ATOM   1637 C CA  . ASN B 2 106 ? 222.463 177.770 171.156 1.00 69.37  ? 106 ASN H CA  1 
ATOM   1638 C C   . ASN B 2 106 ? 222.339 179.273 171.435 1.00 69.37  ? 106 ASN H C   1 
ATOM   1639 O O   . ASN B 2 106 ? 221.228 179.802 171.253 1.00 69.37  ? 106 ASN H O   1 
ATOM   1640 C CB  . ASN B 2 106 ? 222.672 176.979 172.422 1.00 69.37  ? 106 ASN H CB  1 
ATOM   1641 N N   . SER B 2 107 ? 223.425 179.936 171.845 1.00 64.17  ? 107 SER H N   1 
ATOM   1642 C CA  . SER B 2 107 ? 223.359 181.409 172.041 1.00 64.17  ? 107 SER H CA  1 
ATOM   1643 C C   . SER B 2 107 ? 224.279 182.161 171.085 1.00 64.17  ? 107 SER H C   1 
ATOM   1644 O O   . SER B 2 107 ? 225.477 181.837 171.046 1.00 64.17  ? 107 SER H O   1 
ATOM   1645 C CB  . SER B 2 107 ? 223.712 181.776 173.414 1.00 64.17  ? 107 SER H CB  1 
ATOM   1646 O OG  . SER B 2 107 ? 223.041 182.974 173.769 1.00 64.17  ? 107 SER H OG  1 
ATOM   1647 N N   . GLY B 2 108 ? 223.738 183.178 170.413 1.00 62.89  ? 108 GLY H N   1 
ATOM   1648 C CA  . GLY B 2 108 ? 224.521 183.953 169.444 1.00 62.89  ? 108 GLY H CA  1 
ATOM   1649 C C   . GLY B 2 108 ? 225.396 183.029 168.647 1.00 62.89  ? 108 GLY H C   1 
ATOM   1650 O O   . GLY B 2 108 ? 224.833 182.245 167.884 1.00 62.89  ? 108 GLY H O   1 
ATOM   1651 N N   . ASN B 2 109 ? 226.700 183.092 168.872 1.00 60.77  ? 109 ASN H N   1 
ATOM   1652 C CA  . ASN B 2 109 ? 227.674 182.274 168.116 1.00 60.77  ? 109 ASN H CA  1 
ATOM   1653 C C   . ASN B 2 109 ? 227.113 181.941 166.727 1.00 60.77  ? 109 ASN H C   1 
ATOM   1654 O O   . ASN B 2 109 ? 226.757 180.777 166.514 1.00 60.77  ? 109 ASN H O   1 
ATOM   1655 C CB  . ASN B 2 109 ? 228.127 181.108 168.986 1.00 60.77  ? 109 ASN H CB  1 
ATOM   1656 C CG  . ASN B 2 109 ? 229.012 181.572 170.120 1.00 60.77  ? 109 ASN H CG  1 
ATOM   1657 O OD1 . ASN B 2 109 ? 228.525 182.091 171.120 1.00 60.77  ? 109 ASN H OD1 1 
ATOM   1658 N ND2 . ASN B 2 109 ? 230.314 181.405 169.967 1.00 60.77  ? 109 ASN H ND2 1 
ATOM   1659 N N   . TYR B 2 110 ? 227.078 182.904 165.809 1.00 52.63  ? 110 TYR H N   1 
ATOM   1660 C CA  . TYR B 2 110 ? 226.573 182.729 164.454 1.00 52.63  ? 110 TYR H CA  1 
ATOM   1661 C C   . TYR B 2 110 ? 227.666 182.181 163.545 1.00 52.63  ? 110 TYR H C   1 
ATOM   1662 O O   . TYR B 2 110 ? 227.675 182.469 162.347 1.00 52.63  ? 110 TYR H O   1 
ATOM   1663 C CB  . TYR B 2 110 ? 226.088 184.066 163.902 1.00 52.63  ? 110 TYR H CB  1 
ATOM   1664 C CG  . TYR B 2 110 ? 224.664 184.454 164.215 1.00 52.63  ? 110 TYR H CG  1 
ATOM   1665 C CD1 . TYR B 2 110 ? 224.040 184.036 165.373 1.00 52.63  ? 110 TYR H CD1 1 
ATOM   1666 C CD2 . TYR B 2 110 ? 223.975 185.321 163.384 1.00 52.63  ? 110 TYR H CD2 1 
ATOM   1667 C CE1 . TYR B 2 110 ? 222.740 184.422 165.658 1.00 52.63  ? 110 TYR H CE1 1 
ATOM   1668 C CE2 . TYR B 2 110 ? 222.690 185.712 163.657 1.00 52.63  ? 110 TYR H CE2 1 
ATOM   1669 C CZ  . TYR B 2 110 ? 222.076 185.264 164.793 1.00 52.63  ? 110 TYR H CZ  1 
ATOM   1670 O OH  . TYR B 2 110 ? 220.790 185.663 165.059 1.00 52.63  ? 110 TYR H OH  1 
ATOM   1671 N N   . ARG B 2 111 ? 228.576 181.388 164.100 1.00 47.45  ? 111 ARG H N   1 
ATOM   1672 C CA  . ARG B 2 111 ? 229.847 181.071 163.465 1.00 47.45  ? 111 ARG H CA  1 
ATOM   1673 C C   . ARG B 2 111 ? 229.654 180.393 162.113 1.00 47.45  ? 111 ARG H C   1 
ATOM   1674 O O   . ARG B 2 111 ? 228.730 179.607 161.907 1.00 47.45  ? 111 ARG H O   1 
ATOM   1675 C CB  . ARG B 2 111 ? 230.687 180.179 164.377 1.00 47.45  ? 111 ARG H CB  1 
ATOM   1676 C CG  . ARG B 2 111 ? 232.074 179.873 163.840 1.00 47.45  ? 111 ARG H CG  1 
ATOM   1677 C CD  . ARG B 2 111 ? 232.856 178.777 164.587 1.00 47.45  ? 111 ARG H CD  1 
ATOM   1678 N NE  . ARG B 2 111 ? 232.229 177.453 164.595 1.00 47.45  ? 111 ARG H NE  1 
ATOM   1679 C CZ  . ARG B 2 111 ? 231.242 177.064 165.401 1.00 47.45  ? 111 ARG H CZ  1 
ATOM   1680 N NH1 . ARG B 2 111 ? 230.767 177.869 166.340 1.00 47.45  ? 111 ARG H NH1 1 
ATOM   1681 N NH2 . ARG B 2 111 ? 230.763 175.835 165.299 1.00 47.45  ? 111 ARG H NH2 1 
ATOM   1682 N N   . THR B 2 112 ? 230.546 180.723 161.183 1.00 43.28  ? 112 THR H N   1 
ATOM   1683 C CA  . THR B 2 112 ? 230.580 180.143 159.847 1.00 43.28  ? 112 THR H CA  1 
ATOM   1684 C C   . THR B 2 112 ? 231.636 179.047 159.792 1.00 43.28  ? 112 THR H C   1 
ATOM   1685 O O   . THR B 2 112 ? 232.835 179.337 159.832 1.00 43.28  ? 112 THR H O   1 
ATOM   1686 C CB  . THR B 2 112 ? 230.892 181.214 158.802 1.00 43.28  ? 112 THR H CB  1 
ATOM   1687 O OG1 . THR B 2 112 ? 229.759 182.071 158.643 1.00 43.28  ? 112 THR H OG1 1 
ATOM   1688 C CG2 . THR B 2 112 ? 231.219 180.584 157.467 1.00 43.28  ? 112 THR H CG2 1 
ATOM   1689 N N   . ASP B 2 113 ? 231.192 177.792 159.701 1.00 42.00  ? 113 ASP H N   1 
ATOM   1690 C CA  . ASP B 2 113 ? 232.101 176.653 159.618 1.00 42.00  ? 113 ASP H CA  1 
ATOM   1691 C C   . ASP B 2 113 ? 232.265 176.191 158.183 1.00 42.00  ? 113 ASP H C   1 
ATOM   1692 O O   . ASP B 2 113 ? 231.548 176.654 157.294 1.00 42.00  ? 113 ASP H O   1 
ATOM   1693 C CB  . ASP B 2 113 ? 231.602 175.490 160.470 1.00 42.00  ? 113 ASP H CB  1 
ATOM   1694 C CG  . ASP B 2 113 ? 231.683 175.777 161.944 1.00 42.00  ? 113 ASP H CG  1 
ATOM   1695 O OD1 . ASP B 2 113 ? 232.572 176.552 162.346 1.00 42.00  ? 113 ASP H OD1 1 
ATOM   1696 O OD2 . ASP B 2 113 ? 230.856 175.238 162.703 1.00 42.00  ? 113 ASP H OD2 1 
ATOM   1697 N N   . ASP B 2 114 ? 233.225 175.306 157.935 1.00 36.78  ? 114 ASP H N   1 
ATOM   1698 C CA  . ASP B 2 114 ? 233.356 174.714 156.612 1.00 36.78  ? 114 ASP H CA  1 
ATOM   1699 C C   . ASP B 2 114 ? 233.744 173.235 156.706 1.00 36.78  ? 114 ASP H C   1 
ATOM   1700 O O   . ASP B 2 114 ? 234.676 172.779 156.037 1.00 36.78  ? 114 ASP H O   1 
ATOM   1701 C CB  . ASP B 2 114 ? 234.351 175.491 155.760 1.00 36.78  ? 114 ASP H CB  1 
ATOM   1702 C CG  . ASP B 2 114 ? 234.394 174.996 154.356 1.00 36.78  ? 114 ASP H CG  1 
ATOM   1703 O OD1 . ASP B 2 114 ? 233.448 175.275 153.597 1.00 36.78  ? 114 ASP H OD1 1 
ATOM   1704 O OD2 . ASP B 2 114 ? 235.353 174.292 154.018 1.00 36.78  ? 114 ASP H OD2 1 
ATOM   1705 N N   . ALA B 2 115 ? 233.066 172.475 157.559 1.00 30.71  ? 115 ALA H N   1 
ATOM   1706 C CA  . ALA B 2 115 ? 233.349 171.053 157.688 1.00 30.71  ? 115 ALA H CA  1 
ATOM   1707 C C   . ALA B 2 115 ? 232.421 170.248 156.793 1.00 30.71  ? 115 ALA H C   1 
ATOM   1708 O O   . ALA B 2 115 ? 231.304 170.673 156.498 1.00 30.71  ? 115 ALA H O   1 
ATOM   1709 C CB  . ALA B 2 115 ? 233.200 170.598 159.136 1.00 30.71  ? 115 ALA H CB  1 
ATOM   1710 N N   . PHE B 2 116 ? 232.890 169.077 156.365 1.00 27.16  ? 116 PHE H N   1 
ATOM   1711 C CA  . PHE B 2 116 ? 232.170 168.240 155.405 1.00 27.16  ? 116 PHE H CA  1 
ATOM   1712 C C   . PHE B 2 116 ? 231.130 167.405 156.134 1.00 27.16  ? 116 PHE H C   1 
ATOM   1713 O O   . PHE B 2 116 ? 231.388 166.269 156.523 1.00 27.16  ? 116 PHE H O   1 
ATOM   1714 C CB  . PHE B 2 116 ? 233.130 167.331 154.655 1.00 27.16  ? 116 PHE H CB  1 
ATOM   1715 C CG  . PHE B 2 116 ? 234.310 168.030 154.086 1.00 27.16  ? 116 PHE H CG  1 
ATOM   1716 C CD1 . PHE B 2 116 ? 234.162 169.151 153.321 1.00 27.16  ? 116 PHE H CD1 1 
ATOM   1717 C CD2 . PHE B 2 116 ? 235.577 167.565 154.328 1.00 27.16  ? 116 PHE H CD2 1 
ATOM   1718 C CE1 . PHE B 2 116 ? 235.252 169.784 152.807 1.00 27.16  ? 116 PHE H CE1 1 
ATOM   1719 C CE2 . PHE B 2 116 ? 236.666 168.202 153.816 1.00 27.16  ? 116 PHE H CE2 1 
ATOM   1720 C CZ  . PHE B 2 116 ? 236.502 169.311 153.054 1.00 27.16  ? 116 PHE H CZ  1 
ATOM   1721 N N   . ASP B 2 117 ? 229.922 167.944 156.276 1.00 32.19  ? 117 ASP H N   1 
ATOM   1722 C CA  . ASP B 2 117 ? 228.814 167.151 156.797 1.00 32.19  ? 117 ASP H CA  1 
ATOM   1723 C C   . ASP B 2 117 ? 228.334 166.261 155.660 1.00 32.19  ? 117 ASP H C   1 
ATOM   1724 O O   . ASP B 2 117 ? 229.101 166.015 154.729 1.00 32.19  ? 117 ASP H O   1 
ATOM   1725 C CB  . ASP B 2 117 ? 227.705 168.020 157.400 1.00 32.19  ? 117 ASP H CB  1 
ATOM   1726 C CG  . ASP B 2 117 ? 226.813 168.680 156.365 1.00 32.19  ? 117 ASP H CG  1 
ATOM   1727 O OD1 . ASP B 2 117 ? 227.148 168.689 155.166 1.00 32.19  ? 117 ASP H OD1 1 
ATOM   1728 O OD2 . ASP B 2 117 ? 225.749 169.196 156.761 1.00 32.19  ? 117 ASP H OD2 1 
ATOM   1729 N N   . ILE B 2 118 ? 227.091 165.784 155.712 1.00 30.52  ? 118 ILE H N   1 
ATOM   1730 C CA  . ILE B 2 118 ? 226.642 164.589 154.999 1.00 30.52  ? 118 ILE H CA  1 
ATOM   1731 C C   . ILE B 2 118 ? 227.272 164.414 153.621 1.00 30.52  ? 118 ILE H C   1 
ATOM   1732 O O   . ILE B 2 118 ? 227.277 165.328 152.790 1.00 30.52  ? 118 ILE H O   1 
ATOM   1733 C CB  . ILE B 2 118 ? 225.109 164.609 154.883 1.00 30.52  ? 118 ILE H CB  1 
ATOM   1734 C CG1 . ILE B 2 118 ? 224.660 165.711 153.929 1.00 30.52  ? 118 ILE H CG1 1 
ATOM   1735 C CG2 . ILE B 2 118 ? 224.478 164.798 156.246 1.00 30.52  ? 118 ILE H CG2 1 
ATOM   1736 C CD1 . ILE B 2 118 ? 223.210 165.680 153.624 1.00 30.52  ? 118 ILE H CD1 1 
ATOM   1737 N N   . TRP B 2 119 ? 227.830 163.228 153.393 1.00 29.34  ? 119 TRP H N   1 
ATOM   1738 C CA  . TRP B 2 119 ? 228.595 162.883 152.210 1.00 29.34  ? 119 TRP H CA  1 
ATOM   1739 C C   . TRP B 2 119 ? 227.731 162.085 151.246 1.00 29.34  ? 119 TRP H C   1 
ATOM   1740 O O   . TRP B 2 119 ? 226.525 161.930 151.434 1.00 29.34  ? 119 TRP H O   1 
ATOM   1741 C CB  . TRP B 2 119 ? 229.824 162.065 152.586 1.00 29.34  ? 119 TRP H CB  1 
ATOM   1742 C CG  . TRP B 2 119 ? 230.808 162.735 153.460 1.00 29.34  ? 119 TRP H CG  1 
ATOM   1743 C CD1 . TRP B 2 119 ? 230.559 163.421 154.603 1.00 29.34  ? 119 TRP H CD1 1 
ATOM   1744 C CD2 . TRP B 2 119 ? 232.223 162.738 153.289 1.00 29.34  ? 119 TRP H CD2 1 
ATOM   1745 N NE1 . TRP B 2 119 ? 231.732 163.875 155.146 1.00 29.34  ? 119 TRP H NE1 1 
ATOM   1746 C CE2 . TRP B 2 119 ? 232.768 163.465 154.354 1.00 29.34  ? 119 TRP H CE2 1 
ATOM   1747 C CE3 . TRP B 2 119 ? 233.080 162.206 152.330 1.00 29.34  ? 119 TRP H CE3 1 
ATOM   1748 C CZ2 . TRP B 2 119 ? 234.126 163.668 154.489 1.00 29.34  ? 119 TRP H CZ2 1 
ATOM   1749 C CZ3 . TRP B 2 119 ? 234.423 162.410 152.465 1.00 29.34  ? 119 TRP H CZ3 1 
ATOM   1750 C CH2 . TRP B 2 119 ? 234.938 163.135 153.531 1.00 29.34  ? 119 TRP H CH2 1 
ATOM   1751 N N   . GLY B 2 120 ? 228.359 161.555 150.200 1.00 35.77  ? 120 GLY H N   1 
ATOM   1752 C CA  . GLY B 2 120 ? 227.723 160.622 149.305 1.00 35.77  ? 120 GLY H CA  1 
ATOM   1753 C C   . GLY B 2 120 ? 228.314 159.230 149.421 1.00 35.77  ? 120 GLY H C   1 
ATOM   1754 O O   . GLY B 2 120 ? 228.992 158.887 150.390 1.00 35.77  ? 120 GLY H O   1 
ATOM   1755 N N   . GLN B 2 121 ? 228.029 158.418 148.411 1.00 38.18  ? 121 GLN H N   1 
ATOM   1756 C CA  . GLN B 2 121 ? 228.662 157.116 148.276 1.00 38.18  ? 121 GLN H CA  1 
ATOM   1757 C C   . GLN B 2 121 ? 229.899 157.255 147.396 1.00 38.18  ? 121 GLN H C   1 
ATOM   1758 O O   . GLN B 2 121 ? 230.365 158.359 147.116 1.00 38.18  ? 121 GLN H O   1 
ATOM   1759 C CB  . GLN B 2 121 ? 227.671 156.097 147.728 1.00 38.18  ? 121 GLN H CB  1 
ATOM   1760 C CG  . GLN B 2 121 ? 226.512 155.845 148.654 1.00 38.18  ? 121 GLN H CG  1 
ATOM   1761 C CD  . GLN B 2 121 ? 226.954 155.183 149.941 1.00 38.18  ? 121 GLN H CD  1 
ATOM   1762 O OE1 . GLN B 2 121 ? 227.829 154.318 149.939 1.00 38.18  ? 121 GLN H OE1 1 
ATOM   1763 N NE2 . GLN B 2 121 ? 226.351 155.587 151.052 1.00 38.18  ? 121 GLN H NE2 1 
ATOM   1764 N N   . GLY B 2 122 ? 230.456 156.140 146.960 1.00 37.40  ? 122 GLY H N   1 
ATOM   1765 C CA  . GLY B 2 122 ? 231.648 156.159 146.149 1.00 37.40  ? 122 GLY H CA  1 
ATOM   1766 C C   . GLY B 2 122 ? 231.368 155.955 144.674 1.00 37.40  ? 122 GLY H C   1 
ATOM   1767 O O   . GLY B 2 122 ? 230.328 155.435 144.284 1.00 37.40  ? 122 GLY H O   1 
ATOM   1768 N N   . THR B 2 123 ? 232.323 156.386 143.850 1.00 42.29  ? 123 THR H N   1 
ATOM   1769 C CA  . THR B 2 123 ? 232.293 156.162 142.403 1.00 42.29  ? 123 THR H CA  1 
ATOM   1770 C C   . THR B 2 123 ? 233.704 155.761 141.984 1.00 42.29  ? 123 THR H C   1 
ATOM   1771 O O   . THR B 2 123 ? 234.537 156.622 141.698 1.00 42.29  ? 123 THR H O   1 
ATOM   1772 C CB  . THR B 2 123 ? 231.829 157.398 141.652 1.00 42.29  ? 123 THR H CB  1 
ATOM   1773 O OG1 . THR B 2 123 ? 232.696 158.492 141.961 1.00 42.29  ? 123 THR H OG1 1 
ATOM   1774 C CG2 . THR B 2 123 ? 230.419 157.761 142.039 1.00 42.29  ? 123 THR H CG2 1 
ATOM   1775 N N   . MET B 2 124 ? 233.962 154.457 141.943 1.00 51.84  ? 124 MET H N   1 
ATOM   1776 C CA  . MET B 2 124 ? 235.294 153.971 141.610 1.00 51.84  ? 124 MET H CA  1 
ATOM   1777 C C   . MET B 2 124 ? 235.722 154.477 140.239 1.00 51.84  ? 124 MET H C   1 
ATOM   1778 O O   . MET B 2 124 ? 234.970 154.385 139.267 1.00 51.84  ? 124 MET H O   1 
ATOM   1779 C CB  . MET B 2 124 ? 235.313 152.445 141.637 1.00 51.84  ? 124 MET H CB  1 
ATOM   1780 C CG  . MET B 2 124 ? 236.699 151.831 141.691 1.00 51.84  ? 124 MET H CG  1 
ATOM   1781 S SD  . MET B 2 124 ? 237.271 151.523 143.370 1.00 51.84  ? 124 MET H SD  1 
ATOM   1782 C CE  . MET B 2 124 ? 239.044 151.510 143.128 1.00 51.84  ? 124 MET H CE  1 
ATOM   1783 N N   . VAL B 2 125 ? 236.935 155.015 140.162 1.00 47.56  ? 125 VAL H N   1 
ATOM   1784 C CA  . VAL B 2 125 ? 237.490 155.560 138.928 1.00 47.56  ? 125 VAL H CA  1 
ATOM   1785 C C   . VAL B 2 125 ? 238.886 154.977 138.774 1.00 47.56  ? 125 VAL H C   1 
ATOM   1786 O O   . VAL B 2 125 ? 239.838 155.465 139.389 1.00 47.56  ? 125 VAL H O   1 
ATOM   1787 C CB  . VAL B 2 125 ? 237.539 157.087 138.936 1.00 47.56  ? 125 VAL H CB  1 
ATOM   1788 C CG1 . VAL B 2 125 ? 238.151 157.590 137.651 1.00 47.56  ? 125 VAL H CG1 1 
ATOM   1789 C CG2 . VAL B 2 125 ? 236.159 157.655 139.127 1.00 47.56  ? 125 VAL H CG2 1 
ATOM   1790 N N   . THR B 2 126 ? 239.020 153.945 137.953 1.00 57.37  ? 126 THR H N   1 
ATOM   1791 C CA  . THR B 2 126 ? 240.301 153.287 137.751 1.00 57.37  ? 126 THR H CA  1 
ATOM   1792 C C   . THR B 2 126 ? 240.885 153.677 136.402 1.00 57.37  ? 126 THR H C   1 
ATOM   1793 O O   . THR B 2 126 ? 240.183 153.687 135.388 1.00 57.37  ? 126 THR H O   1 
ATOM   1794 C CB  . THR B 2 126 ? 240.153 151.771 137.831 1.00 57.37  ? 126 THR H CB  1 
ATOM   1795 O OG1 . THR B 2 126 ? 239.115 151.352 136.943 1.00 57.37  ? 126 THR H OG1 1 
ATOM   1796 C CG2 . THR B 2 126 ? 239.791 151.357 139.239 1.00 57.37  ? 126 THR H CG2 1 
ATOM   1797 N N   . VAL B 2 127 ? 242.175 153.995 136.398 1.00 65.68  ? 127 VAL H N   1 
ATOM   1798 C CA  . VAL B 2 127 ? 242.878 154.443 135.205 1.00 65.68  ? 127 VAL H CA  1 
ATOM   1799 C C   . VAL B 2 127 ? 244.034 153.491 134.956 1.00 65.68  ? 127 VAL H C   1 
ATOM   1800 O O   . VAL B 2 127 ? 244.977 153.433 135.754 1.00 65.68  ? 127 VAL H O   1 
ATOM   1801 C CB  . VAL B 2 127 ? 243.391 155.879 135.359 1.00 65.68  ? 127 VAL H CB  1 
ATOM   1802 C CG1 . VAL B 2 127 ? 244.002 156.355 134.062 1.00 65.68  ? 127 VAL H CG1 1 
ATOM   1803 C CG2 . VAL B 2 127 ? 242.275 156.793 135.815 1.00 65.68  ? 127 VAL H CG2 1 
ATOM   1804 N N   . SER B 2 128 ? 243.976 152.759 133.847 1.00 68.49  ? 128 SER H N   1 
ATOM   1805 C CA  . SER B 2 128 ? 245.050 151.836 133.510 1.00 68.49  ? 128 SER H CA  1 
ATOM   1806 C C   . SER B 2 128 ? 244.983 151.516 132.025 1.00 68.49  ? 128 SER H C   1 
ATOM   1807 O O   . SER B 2 128 ? 243.980 151.780 131.358 1.00 68.49  ? 128 SER H O   1 
ATOM   1808 C CB  . SER B 2 128 ? 244.976 150.555 134.346 1.00 68.49  ? 128 SER H CB  1 
ATOM   1809 O OG  . SER B 2 128 ? 246.119 149.744 134.133 1.00 68.49  ? 128 SER H OG  1 
ATOM   1810 N N   . SER B 2 129 ? 246.068 150.932 131.522 1.00 72.07  ? 129 SER H N   1 
ATOM   1811 C CA  . SER B 2 129 ? 246.229 150.658 130.102 1.00 72.07  ? 129 SER H CA  1 
ATOM   1812 C C   . SER B 2 129 ? 245.668 149.307 129.677 1.00 72.07  ? 129 SER H C   1 
ATOM   1813 O O   . SER B 2 129 ? 245.682 148.999 128.482 1.00 72.07  ? 129 SER H O   1 
ATOM   1814 C CB  . SER B 2 129 ? 247.710 150.733 129.723 1.00 72.07  ? 129 SER H CB  1 
ATOM   1815 O OG  . SER B 2 129 ? 248.266 151.981 130.093 1.00 72.07  ? 129 SER H OG  1 
ATOM   1816 N N   . ALA B 2 130 ? 245.178 148.499 130.611 1.00 64.96  ? 130 ALA H N   1 
ATOM   1817 C CA  . ALA B 2 130 ? 244.671 147.172 130.277 1.00 64.96  ? 130 ALA H CA  1 
ATOM   1818 C C   . ALA B 2 130 ? 243.386 147.252 129.462 1.00 64.96  ? 130 ALA H C   1 
ATOM   1819 O O   . ALA B 2 130 ? 242.680 146.256 129.304 1.00 64.96  ? 130 ALA H O   1 
ATOM   1820 C CB  . ALA B 2 130 ? 244.442 146.363 131.537 1.00 64.96  ? 130 ALA H CB  1 
ATOM   1821 N N   . ASN C 3 331 ? 240.495 186.465 184.101 1.00 88.24  ? 334 ASN R N   1 
ATOM   1822 C CA  . ASN C 3 331 ? 240.271 185.939 182.759 1.00 88.24  ? 334 ASN R CA  1 
ATOM   1823 C C   . ASN C 3 331 ? 239.817 187.024 181.788 1.00 88.24  ? 334 ASN R C   1 
ATOM   1824 O O   . ASN C 3 331 ? 238.698 187.524 181.875 1.00 88.24  ? 334 ASN R O   1 
ATOM   1825 C CB  . ASN C 3 331 ? 239.245 184.802 182.794 1.00 88.24  ? 334 ASN R CB  1 
ATOM   1826 C CG  . ASN C 3 331 ? 238.000 185.158 183.585 1.00 88.24  ? 334 ASN R CG  1 
ATOM   1827 O OD1 . ASN C 3 331 ? 237.060 184.371 183.677 1.00 88.24  ? 334 ASN R OD1 1 
ATOM   1828 N ND2 . ASN C 3 331 ? 237.991 186.350 184.167 1.00 88.24  ? 334 ASN R ND2 1 
ATOM   1829 N N   . LEU C 3 332 ? 240.689 187.380 180.853 1.00 82.03  ? 335 LEU R N   1 
ATOM   1830 C CA  . LEU C 3 332 ? 240.386 188.378 179.837 1.00 82.03  ? 335 LEU R CA  1 
ATOM   1831 C C   . LEU C 3 332 ? 239.733 187.669 178.660 1.00 82.03  ? 335 LEU R C   1 
ATOM   1832 O O   . LEU C 3 332 ? 240.339 186.777 178.058 1.00 82.03  ? 335 LEU R O   1 
ATOM   1833 C CB  . LEU C 3 332 ? 241.650 189.112 179.393 1.00 82.03  ? 335 LEU R CB  1 
ATOM   1834 C CG  . LEU C 3 332 ? 242.426 189.850 180.483 1.00 82.03  ? 335 LEU R CG  1 
ATOM   1835 C CD1 . LEU C 3 332 ? 243.640 189.045 180.905 1.00 82.03  ? 335 LEU R CD1 1 
ATOM   1836 C CD2 . LEU C 3 332 ? 242.837 191.232 180.012 1.00 82.03  ? 335 LEU R CD2 1 
ATOM   1837 N N   . CYS C 3 333 ? 238.505 188.062 178.337 1.00 83.81  ? 336 CYS R N   1 
ATOM   1838 C CA  . CYS C 3 333 ? 237.764 187.370 177.297 1.00 83.81  ? 336 CYS R CA  1 
ATOM   1839 C C   . CYS C 3 333 ? 238.379 187.623 175.921 1.00 83.81  ? 336 CYS R C   1 
ATOM   1840 O O   . CYS C 3 333 ? 239.060 188.629 175.710 1.00 83.81  ? 336 CYS R O   1 
ATOM   1841 C CB  . CYS C 3 333 ? 236.297 187.780 177.325 1.00 83.81  ? 336 CYS R CB  1 
ATOM   1842 S SG  . CYS C 3 333 ? 235.952 189.516 177.479 1.00 83.81  ? 336 CYS R SG  1 
ATOM   1843 N N   . PRO C 3 334 ? 238.160 186.711 174.968 1.00 68.21  ? 337 PRO R N   1 
ATOM   1844 C CA  . PRO C 3 334 ? 238.983 186.699 173.753 1.00 68.21  ? 337 PRO R CA  1 
ATOM   1845 C C   . PRO C 3 334 ? 238.611 187.744 172.717 1.00 68.21  ? 337 PRO R C   1 
ATOM   1846 O O   . PRO C 3 334 ? 237.870 187.453 171.775 1.00 68.21  ? 337 PRO R O   1 
ATOM   1847 C CB  . PRO C 3 334 ? 238.751 185.289 173.207 1.00 68.21  ? 337 PRO R CB  1 
ATOM   1848 C CG  . PRO C 3 334 ? 237.362 184.972 173.628 1.00 68.21  ? 337 PRO R CG  1 
ATOM   1849 C CD  . PRO C 3 334 ? 237.186 185.603 174.975 1.00 68.21  ? 337 PRO R CD  1 
ATOM   1850 N N   . PHE C 3 335 ? 239.118 188.965 172.872 1.00 55.43  ? 338 PHE R N   1 
ATOM   1851 C CA  . PHE C 3 335 ? 239.041 189.912 171.771 1.00 55.43  ? 338 PHE R CA  1 
ATOM   1852 C C   . PHE C 3 335 ? 240.028 189.552 170.674 1.00 55.43  ? 338 PHE R C   1 
ATOM   1853 O O   . PHE C 3 335 ? 239.802 189.878 169.506 1.00 55.43  ? 338 PHE R O   1 
ATOM   1854 C CB  . PHE C 3 335 ? 239.295 191.327 172.275 1.00 55.43  ? 338 PHE R CB  1 
ATOM   1855 C CG  . PHE C 3 335 ? 238.093 191.971 172.881 1.00 55.43  ? 338 PHE R CG  1 
ATOM   1856 C CD1 . PHE C 3 335 ? 236.833 191.699 172.395 1.00 55.43  ? 338 PHE R CD1 1 
ATOM   1857 C CD2 . PHE C 3 335 ? 238.219 192.836 173.946 1.00 55.43  ? 338 PHE R CD2 1 
ATOM   1858 C CE1 . PHE C 3 335 ? 235.722 192.289 172.953 1.00 55.43  ? 338 PHE R CE1 1 
ATOM   1859 C CE2 . PHE C 3 335 ? 237.112 193.424 174.506 1.00 55.43  ? 338 PHE R CE2 1 
ATOM   1860 C CZ  . PHE C 3 335 ? 235.864 193.150 174.011 1.00 55.43  ? 338 PHE R CZ  1 
ATOM   1861 N N   . GLY C 3 336 ? 241.122 188.876 171.029 1.00 53.97  ? 339 GLY R N   1 
ATOM   1862 C CA  . GLY C 3 336 ? 242.098 188.465 170.040 1.00 53.97  ? 339 GLY R CA  1 
ATOM   1863 C C   . GLY C 3 336 ? 241.600 187.392 169.099 1.00 53.97  ? 339 GLY R C   1 
ATOM   1864 O O   . GLY C 3 336 ? 242.199 187.186 168.040 1.00 53.97  ? 339 GLY R O   1 
ATOM   1865 N N   . GLU C 3 337 ? 240.525 186.697 169.465 1.00 56.91  ? 340 GLU R N   1 
ATOM   1866 C CA  . GLU C 3 337 ? 239.916 185.716 168.580 1.00 56.91  ? 340 GLU R CA  1 
ATOM   1867 C C   . GLU C 3 337 ? 238.880 186.326 167.650 1.00 56.91  ? 340 GLU R C   1 
ATOM   1868 O O   . GLU C 3 337 ? 238.306 185.601 166.834 1.00 56.91  ? 340 GLU R O   1 
ATOM   1869 C CB  . GLU C 3 337 ? 239.268 184.600 169.395 1.00 56.91  ? 340 GLU R CB  1 
ATOM   1870 C CG  . GLU C 3 337 ? 240.257 183.676 170.068 1.00 56.91  ? 340 GLU R CG  1 
ATOM   1871 C CD  . GLU C 3 337 ? 239.607 182.796 171.111 1.00 56.91  ? 340 GLU R CD  1 
ATOM   1872 O OE1 . GLU C 3 337 ? 238.428 182.431 170.931 1.00 56.91  ? 340 GLU R OE1 1 
ATOM   1873 O OE2 . GLU C 3 337 ? 240.274 182.471 172.114 1.00 56.91  ? 340 GLU R OE2 1 
ATOM   1874 N N   . VAL C 3 338 ? 238.615 187.624 167.762 1.00 40.92  ? 341 VAL R N   1 
ATOM   1875 C CA  . VAL C 3 338 ? 237.697 188.317 166.875 1.00 40.92  ? 341 VAL R CA  1 
ATOM   1876 C C   . VAL C 3 338 ? 238.409 189.374 166.042 1.00 40.92  ? 341 VAL R C   1 
ATOM   1877 O O   . VAL C 3 338 ? 238.078 189.569 164.872 1.00 40.92  ? 341 VAL R O   1 
ATOM   1878 C CB  . VAL C 3 338 ? 236.530 188.935 167.671 1.00 40.92  ? 341 VAL R CB  1 
ATOM   1879 C CG1 . VAL C 3 338 ? 235.583 189.657 166.748 1.00 40.92  ? 341 VAL R CG1 1 
ATOM   1880 C CG2 . VAL C 3 338 ? 235.796 187.861 168.426 1.00 40.92  ? 341 VAL R CG2 1 
ATOM   1881 N N   . PHE C 3 339 ? 239.389 190.065 166.620 1.00 38.32  ? 342 PHE R N   1 
ATOM   1882 C CA  . PHE C 3 339 ? 240.094 191.096 165.875 1.00 38.32  ? 342 PHE R CA  1 
ATOM   1883 C C   . PHE C 3 339 ? 241.302 190.565 165.124 1.00 38.32  ? 342 PHE R C   1 
ATOM   1884 O O   . PHE C 3 339 ? 241.875 191.293 164.311 1.00 38.32  ? 342 PHE R O   1 
ATOM   1885 C CB  . PHE C 3 339 ? 240.549 192.219 166.807 1.00 38.32  ? 342 PHE R CB  1 
ATOM   1886 C CG  . PHE C 3 339 ? 239.423 192.952 167.456 1.00 38.32  ? 342 PHE R CG  1 
ATOM   1887 C CD1 . PHE C 3 339 ? 238.675 193.863 166.755 1.00 38.32  ? 342 PHE R CD1 1 
ATOM   1888 C CD2 . PHE C 3 339 ? 239.119 192.735 168.779 1.00 38.32  ? 342 PHE R CD2 1 
ATOM   1889 C CE1 . PHE C 3 339 ? 237.635 194.522 167.362 1.00 38.32  ? 342 PHE R CE1 1 
ATOM   1890 C CE2 . PHE C 3 339 ? 238.087 193.400 169.382 1.00 38.32  ? 342 PHE R CE2 1 
ATOM   1891 C CZ  . PHE C 3 339 ? 237.349 194.296 168.672 1.00 38.32  ? 342 PHE R CZ  1 
ATOM   1892 N N   . ASN C 3 340 ? 241.711 189.326 165.380 1.00 41.99  ? 343 ASN R N   1 
ATOM   1893 C CA  . ASN C 3 340 ? 242.871 188.745 164.720 1.00 41.99  ? 343 ASN R CA  1 
ATOM   1894 C C   . ASN C 3 340 ? 242.541 187.442 164.007 1.00 41.99  ? 343 ASN R C   1 
ATOM   1895 O O   . ASN C 3 340 ? 243.449 186.667 163.696 1.00 41.99  ? 343 ASN R O   1 
ATOM   1896 C CB  . ASN C 3 340 ? 244.000 188.517 165.726 1.00 41.99  ? 343 ASN R CB  1 
ATOM   1897 C CG  . ASN C 3 340 ? 245.050 189.604 165.680 1.00 41.99  ? 343 ASN R CG  1 
ATOM   1898 O OD1 . ASN C 3 340 ? 245.246 190.247 164.651 1.00 41.99  ? 343 ASN R OD1 1 
ATOM   1899 N ND2 . ASN C 3 340 ? 245.744 189.805 166.794 1.00 41.99  ? 343 ASN R ND2 1 
ATOM   1900 N N   . ALA C 3 341 ? 241.264 187.181 163.746 1.00 35.70  ? 344 ALA R N   1 
ATOM   1901 C CA  . ALA C 3 341 ? 240.889 185.947 163.077 1.00 35.70  ? 344 ALA R CA  1 
ATOM   1902 C C   . ALA C 3 341 ? 241.539 185.885 161.704 1.00 35.70  ? 344 ALA R C   1 
ATOM   1903 O O   . ALA C 3 341 ? 241.752 186.905 161.047 1.00 35.70  ? 344 ALA R O   1 
ATOM   1904 C CB  . ALA C 3 341 ? 239.372 185.841 162.951 1.00 35.70  ? 344 ALA R CB  1 
ATOM   1905 N N   . THR C 3 342 ? 241.878 184.671 161.280 1.00 30.05  ? 345 THR R N   1 
ATOM   1906 C CA  . THR C 3 342 ? 242.686 184.520 160.080 1.00 30.05  ? 345 THR R CA  1 
ATOM   1907 C C   . THR C 3 342 ? 241.904 184.883 158.825 1.00 30.05  ? 345 THR R C   1 
ATOM   1908 O O   . THR C 3 342 ? 242.473 185.426 157.875 1.00 30.05  ? 345 THR R O   1 
ATOM   1909 C CB  . THR C 3 342 ? 243.216 183.097 159.984 1.00 30.05  ? 345 THR R CB  1 
ATOM   1910 O OG1 . THR C 3 342 ? 243.935 182.777 161.178 1.00 30.05  ? 345 THR R OG1 1 
ATOM   1911 C CG2 . THR C 3 342 ? 244.173 183.001 158.833 1.00 30.05  ? 345 THR R CG2 1 
ATOM   1912 N N   . ARG C 3 343 ? 240.606 184.593 158.795 1.00 25.88  ? 346 ARG R N   1 
ATOM   1913 C CA  . ARG C 3 343 ? 239.760 184.994 157.682 1.00 25.88  ? 346 ARG R CA  1 
ATOM   1914 C C   . ARG C 3 343 ? 238.403 185.440 158.206 1.00 25.88  ? 346 ARG R C   1 
ATOM   1915 O O   . ARG C 3 343 ? 237.823 184.790 159.079 1.00 25.88  ? 346 ARG R O   1 
ATOM   1916 C CB  . ARG C 3 343 ? 239.595 183.858 156.675 1.00 25.88  ? 346 ARG R CB  1 
ATOM   1917 C CG  . ARG C 3 343 ? 238.990 182.612 157.268 1.00 25.88  ? 346 ARG R CG  1 
ATOM   1918 C CD  . ARG C 3 343 ? 238.675 181.569 156.219 1.00 25.88  ? 346 ARG R CD  1 
ATOM   1919 N NE  . ARG C 3 343 ? 237.979 180.440 156.818 1.00 25.88  ? 346 ARG R NE  1 
ATOM   1920 C CZ  . ARG C 3 343 ? 237.316 179.519 156.134 1.00 25.88  ? 346 ARG R CZ  1 
ATOM   1921 N NH1 . ARG C 3 343 ? 236.711 178.533 156.771 1.00 25.88  ? 346 ARG R NH1 1 
ATOM   1922 N NH2 . ARG C 3 343 ? 237.240 179.595 154.817 1.00 25.88  ? 346 ARG R NH2 1 
ATOM   1923 N N   . PHE C 3 344 ? 237.905 186.553 157.675 1.00 25.71  ? 347 PHE R N   1 
ATOM   1924 C CA  . PHE C 3 344 ? 236.648 187.157 158.090 1.00 25.71  ? 347 PHE R CA  1 
ATOM   1925 C C   . PHE C 3 344 ? 235.519 186.682 157.190 1.00 25.71  ? 347 PHE R C   1 
ATOM   1926 O O   . PHE C 3 344 ? 235.734 186.231 156.067 1.00 25.71  ? 347 PHE R O   1 
ATOM   1927 C CB  . PHE C 3 344 ? 236.733 188.683 158.042 1.00 25.71  ? 347 PHE R CB  1 
ATOM   1928 C CG  . PHE C 3 344 ? 237.125 189.323 159.339 1.00 25.71  ? 347 PHE R CG  1 
ATOM   1929 C CD1 . PHE C 3 344 ? 238.315 189.016 159.948 1.00 25.71  ? 347 PHE R CD1 1 
ATOM   1930 C CD2 . PHE C 3 344 ? 236.302 190.248 159.936 1.00 25.71  ? 347 PHE R CD2 1 
ATOM   1931 C CE1 . PHE C 3 344 ? 238.667 189.612 161.128 1.00 25.71  ? 347 PHE R CE1 1 
ATOM   1932 C CE2 . PHE C 3 344 ? 236.653 190.838 161.116 1.00 25.71  ? 347 PHE R CE2 1 
ATOM   1933 C CZ  . PHE C 3 344 ? 237.833 190.519 161.711 1.00 25.71  ? 347 PHE R CZ  1 
ATOM   1934 N N   . ALA C 3 345 ? 234.298 186.825 157.683 1.00 19.81  ? 348 ALA R N   1 
ATOM   1935 C CA  . ALA C 3 345 ? 233.117 186.325 156.999 1.00 19.81  ? 348 ALA R CA  1 
ATOM   1936 C C   . ALA C 3 345 ? 232.441 187.427 156.199 1.00 19.81  ? 348 ALA R C   1 
ATOM   1937 O O   . ALA C 3 345 ? 232.182 188.508 156.723 1.00 19.81  ? 348 ALA R O   1 
ATOM   1938 C CB  . ALA C 3 345 ? 232.131 185.746 158.006 1.00 19.81  ? 348 ALA R CB  1 
ATOM   1939 N N   . SER C 3 346 ? 232.121 187.129 154.943 1.00 18.93  ? 349 SER R N   1 
ATOM   1940 C CA  . SER C 3 346 ? 231.543 188.114 154.041 1.00 18.93  ? 349 SER R CA  1 
ATOM   1941 C C   . SER C 3 346 ? 230.286 188.731 154.634 1.00 18.93  ? 349 SER R C   1 
ATOM   1942 O O   . SER C 3 346 ? 229.670 188.189 155.548 1.00 18.93  ? 349 SER R O   1 
ATOM   1943 C CB  . SER C 3 346 ? 231.225 187.474 152.699 1.00 18.93  ? 349 SER R CB  1 
ATOM   1944 O OG  . SER C 3 346 ? 230.278 186.441 152.857 1.00 18.93  ? 349 SER R OG  1 
ATOM   1945 N N   . VAL C 3 347 ? 229.901 189.885 154.091 1.00 20.89  ? 350 VAL R N   1 
ATOM   1946 C CA  . VAL C 3 347 ? 228.926 190.731 154.772 1.00 20.89  ? 350 VAL R CA  1 
ATOM   1947 C C   . VAL C 3 347 ? 227.541 190.099 154.780 1.00 20.89  ? 350 VAL R C   1 
ATOM   1948 O O   . VAL C 3 347 ? 226.823 190.179 155.781 1.00 20.89  ? 350 VAL R O   1 
ATOM   1949 C CB  . VAL C 3 347 ? 228.912 192.134 154.148 1.00 20.89  ? 350 VAL R CB  1 
ATOM   1950 C CG1 . VAL C 3 347 ? 228.674 192.045 152.684 1.00 20.89  ? 350 VAL R CG1 1 
ATOM   1951 C CG2 . VAL C 3 347 ? 227.838 192.962 154.782 1.00 20.89  ? 350 VAL R CG2 1 
ATOM   1952 N N   . TYR C 3 348 ? 227.145 189.444 153.688 1.00 24.14  ? 351 TYR R N   1 
ATOM   1953 C CA  . TYR C 3 348 ? 225.778 188.941 153.586 1.00 24.14  ? 351 TYR R CA  1 
ATOM   1954 C C   . TYR C 3 348 ? 225.466 187.853 154.599 1.00 24.14  ? 351 TYR R C   1 
ATOM   1955 O O   . TYR C 3 348 ? 224.291 187.540 154.793 1.00 24.14  ? 351 TYR R O   1 
ATOM   1956 C CB  . TYR C 3 348 ? 225.505 188.422 152.175 1.00 24.14  ? 351 TYR R CB  1 
ATOM   1957 C CG  . TYR C 3 348 ? 225.920 186.995 151.944 1.00 24.14  ? 351 TYR R CG  1 
ATOM   1958 C CD1 . TYR C 3 348 ? 227.240 186.672 151.708 1.00 24.14  ? 351 TYR R CD1 1 
ATOM   1959 C CD2 . TYR C 3 348 ? 224.995 185.974 151.946 1.00 24.14  ? 351 TYR R CD2 1 
ATOM   1960 C CE1 . TYR C 3 348 ? 227.627 185.373 151.495 1.00 24.14  ? 351 TYR R CE1 1 
ATOM   1961 C CE2 . TYR C 3 348 ? 225.374 184.673 151.732 1.00 24.14  ? 351 TYR R CE2 1 
ATOM   1962 C CZ  . TYR C 3 348 ? 226.692 184.378 151.509 1.00 24.14  ? 351 TYR R CZ  1 
ATOM   1963 O OH  . TYR C 3 348 ? 227.080 183.081 151.296 1.00 24.14  ? 351 TYR R OH  1 
ATOM   1964 N N   . ALA C 3 349 ? 226.475 187.278 155.241 1.00 23.13  ? 352 ALA R N   1 
ATOM   1965 C CA  . ALA C 3 349 ? 226.316 186.276 156.287 1.00 23.13  ? 352 ALA R CA  1 
ATOM   1966 C C   . ALA C 3 349 ? 227.210 186.610 157.464 1.00 23.13  ? 352 ALA R C   1 
ATOM   1967 O O   . ALA C 3 349 ? 227.959 185.770 157.961 1.00 23.13  ? 352 ALA R O   1 
ATOM   1968 C CB  . ALA C 3 349 ? 226.628 184.881 155.770 1.00 23.13  ? 352 ALA R CB  1 
ATOM   1969 N N   . TRP C 3 350 ? 227.145 187.860 157.915 1.00 26.31  ? 353 TRP R N   1 
ATOM   1970 C CA  . TRP C 3 350 ? 228.084 188.360 158.909 1.00 26.31  ? 353 TRP R CA  1 
ATOM   1971 C C   . TRP C 3 350 ? 228.065 187.517 160.170 1.00 26.31  ? 353 TRP R C   1 
ATOM   1972 O O   . TRP C 3 350 ? 227.007 187.142 160.669 1.00 26.31  ? 353 TRP R O   1 
ATOM   1973 C CB  . TRP C 3 350 ? 227.754 189.801 159.259 1.00 26.31  ? 353 TRP R CB  1 
ATOM   1974 C CG  . TRP C 3 350 ? 226.307 190.062 159.420 1.00 26.31  ? 353 TRP R CG  1 
ATOM   1975 C CD1 . TRP C 3 350 ? 225.440 190.449 158.452 1.00 26.31  ? 353 TRP R CD1 1 
ATOM   1976 C CD2 . TRP C 3 350 ? 225.550 189.978 160.626 1.00 26.31  ? 353 TRP R CD2 1 
ATOM   1977 N NE1 . TRP C 3 350 ? 224.186 190.606 158.975 1.00 26.31  ? 353 TRP R NE1 1 
ATOM   1978 C CE2 . TRP C 3 350 ? 224.229 190.322 160.312 1.00 26.31  ? 353 TRP R CE2 1 
ATOM   1979 C CE3 . TRP C 3 350 ? 225.862 189.646 161.941 1.00 26.31  ? 353 TRP R CE3 1 
ATOM   1980 C CZ2 . TRP C 3 350 ? 223.222 190.337 161.260 1.00 26.31  ? 353 TRP R CZ2 1 
ATOM   1981 C CZ3 . TRP C 3 350 ? 224.861 189.659 162.878 1.00 26.31  ? 353 TRP R CZ3 1 
ATOM   1982 C CH2 . TRP C 3 350 ? 223.558 190.003 162.536 1.00 26.31  ? 353 TRP R CH2 1 
ATOM   1983 N N   . ASN C 3 351 ? 229.248 187.236 160.695 1.00 28.99  ? 354 ASN R N   1 
ATOM   1984 C CA  . ASN C 3 351 ? 229.387 186.378 161.861 1.00 28.99  ? 354 ASN R CA  1 
ATOM   1985 C C   . ASN C 3 351 ? 228.886 187.110 163.099 1.00 28.99  ? 354 ASN R C   1 
ATOM   1986 O O   . ASN C 3 351 ? 228.337 188.209 163.030 1.00 28.99  ? 354 ASN R O   1 
ATOM   1987 C CB  . ASN C 3 351 ? 230.834 185.942 162.024 1.00 28.99  ? 354 ASN R CB  1 
ATOM   1988 C CG  . ASN C 3 351 ? 231.182 184.774 161.157 1.00 28.99  ? 354 ASN R CG  1 
ATOM   1989 O OD1 . ASN C 3 351 ? 230.381 184.338 160.340 1.00 28.99  ? 354 ASN R OD1 1 
ATOM   1990 N ND2 . ASN C 3 351 ? 232.387 184.258 161.320 1.00 28.99  ? 354 ASN R ND2 1 
ATOM   1991 N N   . ARG C 3 352 ? 229.067 186.486 164.257 1.00 37.81  ? 355 ARG R N   1 
ATOM   1992 C CA  . ARG C 3 352 ? 228.665 187.058 165.531 1.00 37.81  ? 355 ARG R CA  1 
ATOM   1993 C C   . ARG C 3 352 ? 229.252 186.207 166.639 1.00 37.81  ? 355 ARG R C   1 
ATOM   1994 O O   . ARG C 3 352 ? 229.361 184.989 166.502 1.00 37.81  ? 355 ARG R O   1 
ATOM   1995 C CB  . ARG C 3 352 ? 227.143 187.116 165.669 1.00 37.81  ? 355 ARG R CB  1 
ATOM   1996 C CG  . ARG C 3 352 ? 226.655 187.587 167.018 1.00 37.81  ? 355 ARG R CG  1 
ATOM   1997 C CD  . ARG C 3 352 ? 225.160 187.743 167.003 1.00 37.81  ? 355 ARG R CD  1 
ATOM   1998 N NE  . ARG C 3 352 ? 224.712 188.828 167.860 1.00 37.81  ? 355 ARG R NE  1 
ATOM   1999 C CZ  . ARG C 3 352 ? 224.426 190.044 167.418 1.00 37.81  ? 355 ARG R CZ  1 
ATOM   2000 N NH1 . ARG C 3 352 ? 224.549 190.329 166.133 1.00 37.81  ? 355 ARG R NH1 1 
ATOM   2001 N NH2 . ARG C 3 352 ? 224.017 190.977 168.260 1.00 37.81  ? 355 ARG R NH2 1 
ATOM   2002 N N   . LYS C 3 353 ? 229.630 186.856 167.732 1.00 43.95  ? 356 LYS R N   1 
ATOM   2003 C CA  . LYS C 3 353 ? 230.141 186.148 168.892 1.00 43.95  ? 356 LYS R CA  1 
ATOM   2004 C C   . LYS C 3 353 ? 229.632 186.819 170.152 1.00 43.95  ? 356 LYS R C   1 
ATOM   2005 O O   . LYS C 3 353 ? 229.661 188.045 170.261 1.00 43.95  ? 356 LYS R O   1 
ATOM   2006 C CB  . LYS C 3 353 ? 231.667 186.113 168.902 1.00 43.95  ? 356 LYS R CB  1 
ATOM   2007 C CG  . LYS C 3 353 ? 232.234 185.296 170.036 1.00 43.95  ? 356 LYS R CG  1 
ATOM   2008 C CD  . LYS C 3 353 ? 233.741 185.320 170.038 1.00 43.95  ? 356 LYS R CD  1 
ATOM   2009 C CE  . LYS C 3 353 ? 234.274 184.285 170.997 1.00 43.95  ? 356 LYS R CE  1 
ATOM   2010 N NZ  . LYS C 3 353 ? 233.264 183.220 171.229 1.00 43.95  ? 356 LYS R NZ  1 
ATOM   2011 N N   . ARG C 3 354 ? 229.171 186.015 171.098 1.00 49.99  ? 357 ARG R N   1 
ATOM   2012 C CA  . ARG C 3 354 ? 228.686 186.521 172.370 1.00 49.99  ? 357 ARG R CA  1 
ATOM   2013 C C   . ARG C 3 354 ? 229.791 186.430 173.409 1.00 49.99  ? 357 ARG R C   1 
ATOM   2014 O O   . ARG C 3 354 ? 230.507 185.429 173.483 1.00 49.99  ? 357 ARG R O   1 
ATOM   2015 C CB  . ARG C 3 354 ? 227.461 185.747 172.847 1.00 49.99  ? 357 ARG R CB  1 
ATOM   2016 C CG  . ARG C 3 354 ? 226.706 186.441 173.953 1.00 49.99  ? 357 ARG R CG  1 
ATOM   2017 C CD  . ARG C 3 354 ? 227.053 185.863 175.306 1.00 49.99  ? 357 ARG R CD  1 
ATOM   2018 N NE  . ARG C 3 354 ? 226.485 184.535 175.490 1.00 49.99  ? 357 ARG R NE  1 
ATOM   2019 C CZ  . ARG C 3 354 ? 225.212 184.305 175.787 1.00 49.99  ? 357 ARG R CZ  1 
ATOM   2020 N NH1 . ARG C 3 354 ? 224.782 183.061 175.933 1.00 49.99  ? 357 ARG R NH1 1 
ATOM   2021 N NH2 . ARG C 3 354 ? 224.369 185.316 175.943 1.00 49.99  ? 357 ARG R NH2 1 
ATOM   2022 N N   . ILE C 3 355 ? 229.925 187.484 174.206 1.00 51.39  ? 358 ILE R N   1 
ATOM   2023 C CA  . ILE C 3 355 ? 230.965 187.593 175.218 1.00 51.39  ? 358 ILE R CA  1 
ATOM   2024 C C   . ILE C 3 355 ? 230.295 187.809 176.563 1.00 51.39  ? 358 ILE R C   1 
ATOM   2025 O O   . ILE C 3 355 ? 229.511 188.751 176.722 1.00 51.39  ? 358 ILE R O   1 
ATOM   2026 C CB  . ILE C 3 355 ? 231.931 188.745 174.906 1.00 51.39  ? 358 ILE R CB  1 
ATOM   2027 C CG1 . ILE C 3 355 ? 232.827 188.394 173.724 1.00 51.39  ? 358 ILE R CG1 1 
ATOM   2028 C CG2 . ILE C 3 355 ? 232.763 189.062 176.112 1.00 51.39  ? 358 ILE R CG2 1 
ATOM   2029 C CD1 . ILE C 3 355 ? 233.481 189.592 173.090 1.00 51.39  ? 358 ILE R CD1 1 
ATOM   2030 N N   . SER C 3 356 ? 230.603 186.946 177.528 1.00 68.27  ? 359 SER R N   1 
ATOM   2031 C CA  . SER C 3 356 ? 230.056 187.086 178.869 1.00 68.27  ? 359 SER R CA  1 
ATOM   2032 C C   . SER C 3 356 ? 231.010 186.450 179.866 1.00 68.27  ? 359 SER R C   1 
ATOM   2033 O O   . SER C 3 356 ? 231.808 185.576 179.519 1.00 68.27  ? 359 SER R O   1 
ATOM   2034 C CB  . SER C 3 356 ? 228.670 186.451 178.983 1.00 68.27  ? 359 SER R CB  1 
ATOM   2035 O OG  . SER C 3 356 ? 228.771 185.040 179.000 1.00 68.27  ? 359 SER R OG  1 
ATOM   2036 N N   . ASN C 3 357 ? 230.911 186.903 181.118 1.00 84.05  ? 360 ASN R N   1 
ATOM   2037 C CA  . ASN C 3 357 ? 231.744 186.419 182.219 1.00 84.05  ? 360 ASN R CA  1 
ATOM   2038 C C   . ASN C 3 357 ? 233.231 186.591 181.907 1.00 84.05  ? 360 ASN R C   1 
ATOM   2039 O O   . ASN C 3 357 ? 233.982 185.624 181.776 1.00 84.05  ? 360 ASN R O   1 
ATOM   2040 C CB  . ASN C 3 357 ? 231.423 184.959 182.556 1.00 84.05  ? 360 ASN R CB  1 
ATOM   2041 C CG  . ASN C 3 357 ? 230.143 184.812 183.345 1.00 84.05  ? 360 ASN R CG  1 
ATOM   2042 O OD1 . ASN C 3 357 ? 229.804 185.667 184.161 1.00 84.05  ? 360 ASN R OD1 1 
ATOM   2043 N ND2 . ASN C 3 357 ? 229.427 183.719 183.115 1.00 84.05  ? 360 ASN R ND2 1 
ATOM   2044 N N   . CYS C 3 358 ? 233.650 187.848 181.786 1.00 89.44  ? 361 CYS R N   1 
ATOM   2045 C CA  . CYS C 3 358 ? 235.052 188.138 181.533 1.00 89.44  ? 361 CYS R CA  1 
ATOM   2046 C C   . CYS C 3 358 ? 235.388 189.512 182.088 1.00 89.44  ? 361 CYS R C   1 
ATOM   2047 O O   . CYS C 3 358 ? 234.507 190.311 182.406 1.00 89.44  ? 361 CYS R O   1 
ATOM   2048 C CB  . CYS C 3 358 ? 235.385 188.097 180.044 1.00 89.44  ? 361 CYS R CB  1 
ATOM   2049 S SG  . CYS C 3 358 ? 234.710 189.473 179.082 1.00 89.44  ? 361 CYS R SG  1 
ATOM   2050 N N   . VAL C 3 359 ? 236.683 189.778 182.194 1.00 83.91  ? 362 VAL R N   1 
ATOM   2051 C CA  . VAL C 3 359 ? 237.199 191.090 182.558 1.00 83.91  ? 362 VAL R CA  1 
ATOM   2052 C C   . VAL C 3 359 ? 237.814 191.674 181.295 1.00 83.91  ? 362 VAL R C   1 
ATOM   2053 O O   . VAL C 3 359 ? 238.984 191.424 180.987 1.00 83.91  ? 362 VAL R O   1 
ATOM   2054 C CB  . VAL C 3 359 ? 238.221 191.011 183.695 1.00 83.91  ? 362 VAL R CB  1 
ATOM   2055 C CG1 . VAL C 3 359 ? 238.702 192.401 184.068 1.00 83.91  ? 362 VAL R CG1 1 
ATOM   2056 C CG2 . VAL C 3 359 ? 237.618 190.313 184.896 1.00 83.91  ? 362 VAL R CG2 1 
ATOM   2057 N N   . ALA C 3 360 ? 237.031 192.452 180.557 1.00 72.12  ? 363 ALA R N   1 
ATOM   2058 C CA  . ALA C 3 360 ? 237.434 192.954 179.252 1.00 72.12  ? 363 ALA R CA  1 
ATOM   2059 C C   . ALA C 3 360 ? 237.955 194.375 179.379 1.00 72.12  ? 363 ALA R C   1 
ATOM   2060 O O   . ALA C 3 360 ? 237.316 195.217 180.016 1.00 72.12  ? 363 ALA R O   1 
ATOM   2061 C CB  . ALA C 3 360 ? 236.262 192.920 178.274 1.00 72.12  ? 363 ALA R CB  1 
ATOM   2062 N N   . ASP C 3 361 ? 239.104 194.640 178.768 1.00 70.39  ? 364 ASP R N   1 
ATOM   2063 C CA  . ASP C 3 361 ? 239.682 195.976 178.739 1.00 70.39  ? 364 ASP R CA  1 
ATOM   2064 C C   . ASP C 3 361 ? 239.562 196.561 177.339 1.00 70.39  ? 364 ASP R C   1 
ATOM   2065 O O   . ASP C 3 361 ? 239.916 195.913 176.351 1.00 70.39  ? 364 ASP R O   1 
ATOM   2066 C CB  . ASP C 3 361 ? 241.133 195.971 179.232 1.00 70.39  ? 364 ASP R CB  1 
ATOM   2067 C CG  . ASP C 3 361 ? 242.070 195.130 178.370 1.00 70.39  ? 364 ASP R CG  1 
ATOM   2068 O OD1 . ASP C 3 361 ? 241.632 194.487 177.397 1.00 70.39  ? 364 ASP R OD1 1 
ATOM   2069 O OD2 . ASP C 3 361 ? 243.281 195.121 178.675 1.00 70.39  ? 364 ASP R OD2 1 
ATOM   2070 N N   . TYR C 3 362 ? 239.017 197.767 177.254 1.00 62.07  ? 365 TYR R N   1 
ATOM   2071 C CA  . TYR C 3 362 ? 238.928 198.474 175.989 1.00 62.07  ? 365 TYR R CA  1 
ATOM   2072 C C   . TYR C 3 362 ? 240.022 199.518 175.824 1.00 62.07  ? 365 TYR R C   1 
ATOM   2073 O O   . TYR C 3 362 ? 240.070 200.187 174.789 1.00 62.07  ? 365 TYR R O   1 
ATOM   2074 C CB  . TYR C 3 362 ? 237.551 199.119 175.854 1.00 62.07  ? 365 TYR R CB  1 
ATOM   2075 C CG  . TYR C 3 362 ? 236.431 198.196 176.262 1.00 62.07  ? 365 TYR R CG  1 
ATOM   2076 C CD1 . TYR C 3 362 ? 235.987 197.199 175.416 1.00 62.07  ? 365 TYR R CD1 1 
ATOM   2077 C CD2 . TYR C 3 362 ? 235.824 198.318 177.496 1.00 62.07  ? 365 TYR R CD2 1 
ATOM   2078 C CE1 . TYR C 3 362 ? 234.968 196.353 175.787 1.00 62.07  ? 365 TYR R CE1 1 
ATOM   2079 C CE2 . TYR C 3 362 ? 234.804 197.476 177.874 1.00 62.07  ? 365 TYR R CE2 1 
ATOM   2080 C CZ  . TYR C 3 362 ? 234.381 196.498 177.018 1.00 62.07  ? 365 TYR R CZ  1 
ATOM   2081 O OH  . TYR C 3 362 ? 233.364 195.661 177.401 1.00 62.07  ? 365 TYR R OH  1 
ATOM   2082 N N   . SER C 3 363 ? 240.898 199.674 176.817 1.00 68.66  ? 366 SER R N   1 
ATOM   2083 C CA  . SER C 3 363 ? 242.030 200.580 176.663 1.00 68.66  ? 366 SER R CA  1 
ATOM   2084 C C   . SER C 3 363 ? 243.002 200.069 175.610 1.00 68.66  ? 366 SER R C   1 
ATOM   2085 O O   . SER C 3 363 ? 243.517 200.850 174.802 1.00 68.66  ? 366 SER R O   1 
ATOM   2086 C CB  . SER C 3 363 ? 242.741 200.764 178.000 1.00 68.66  ? 366 SER R CB  1 
ATOM   2087 O OG  . SER C 3 363 ? 243.383 199.565 178.390 1.00 68.66  ? 366 SER R OG  1 
ATOM   2088 N N   . VAL C 3 364 ? 243.267 198.762 175.603 1.00 68.49  ? 367 VAL R N   1 
ATOM   2089 C CA  . VAL C 3 364 ? 244.141 198.195 174.583 1.00 68.49  ? 367 VAL R CA  1 
ATOM   2090 C C   . VAL C 3 364 ? 243.519 198.335 173.203 1.00 68.49  ? 367 VAL R C   1 
ATOM   2091 O O   . VAL C 3 364 ? 244.228 198.528 172.208 1.00 68.49  ? 367 VAL R O   1 
ATOM   2092 C CB  . VAL C 3 364 ? 244.473 196.728 174.917 1.00 68.49  ? 367 VAL R CB  1 
ATOM   2093 C CG1 . VAL C 3 364 ? 243.222 195.870 174.890 1.00 68.49  ? 367 VAL R CG1 1 
ATOM   2094 C CG2 . VAL C 3 364 ? 245.504 196.186 173.943 1.00 68.49  ? 367 VAL R CG2 1 
ATOM   2095 N N   . LEU C 3 365 ? 242.193 198.240 173.113 1.00 64.07  ? 368 LEU R N   1 
ATOM   2096 C CA  . LEU C 3 365 ? 241.529 198.382 171.824 1.00 64.07  ? 368 LEU R CA  1 
ATOM   2097 C C   . LEU C 3 365 ? 241.580 199.821 171.334 1.00 64.07  ? 368 LEU R C   1 
ATOM   2098 O O   . LEU C 3 365 ? 241.920 200.080 170.176 1.00 64.07  ? 368 LEU R O   1 
ATOM   2099 C CB  . LEU C 3 365 ? 240.084 197.907 171.931 1.00 64.07  ? 368 LEU R CB  1 
ATOM   2100 C CG  . LEU C 3 365 ? 239.800 196.495 171.444 1.00 64.07  ? 368 LEU R CG  1 
ATOM   2101 C CD1 . LEU C 3 365 ? 240.670 195.498 172.170 1.00 64.07  ? 368 LEU R CD1 1 
ATOM   2102 C CD2 . LEU C 3 365 ? 238.345 196.190 171.683 1.00 64.07  ? 368 LEU R CD2 1 
ATOM   2103 N N   . TYR C 3 366 ? 241.247 200.773 172.206 1.00 65.99  ? 369 TYR R N   1 
ATOM   2104 C CA  . TYR C 3 366 ? 241.152 202.160 171.770 1.00 65.99  ? 369 TYR R CA  1 
ATOM   2105 C C   . TYR C 3 366 ? 242.511 202.727 171.397 1.00 65.99  ? 369 TYR R C   1 
ATOM   2106 O O   . TYR C 3 366 ? 242.633 203.453 170.404 1.00 65.99  ? 369 TYR R O   1 
ATOM   2107 C CB  . TYR C 3 366 ? 240.509 203.019 172.851 1.00 65.99  ? 369 TYR R CB  1 
ATOM   2108 C CG  . TYR C 3 366 ? 240.359 204.456 172.424 1.00 65.99  ? 369 TYR R CG  1 
ATOM   2109 C CD1 . TYR C 3 366 ? 239.370 204.831 171.533 1.00 65.99  ? 369 TYR R CD1 1 
ATOM   2110 C CD2 . TYR C 3 366 ? 241.211 205.435 172.904 1.00 65.99  ? 369 TYR R CD2 1 
ATOM   2111 C CE1 . TYR C 3 366 ? 239.230 206.142 171.133 1.00 65.99  ? 369 TYR R CE1 1 
ATOM   2112 C CE2 . TYR C 3 366 ? 241.076 206.752 172.509 1.00 65.99  ? 369 TYR R CE2 1 
ATOM   2113 C CZ  . TYR C 3 366 ? 240.083 207.098 171.624 1.00 65.99  ? 369 TYR R CZ  1 
ATOM   2114 O OH  . TYR C 3 366 ? 239.943 208.406 171.227 1.00 65.99  ? 369 TYR R OH  1 
ATOM   2115 N N   . ASN C 3 367 ? 243.541 202.422 172.181 1.00 66.85  ? 370 ASN R N   1 
ATOM   2116 C CA  . ASN C 3 367 ? 244.851 203.037 171.983 1.00 66.85  ? 370 ASN R CA  1 
ATOM   2117 C C   . ASN C 3 367 ? 245.732 202.124 171.130 1.00 66.85  ? 370 ASN R C   1 
ATOM   2118 O O   . ASN C 3 367 ? 246.671 201.476 171.592 1.00 66.85  ? 370 ASN R O   1 
ATOM   2119 C CB  . ASN C 3 367 ? 245.485 203.368 173.325 1.00 66.85  ? 370 ASN R CB  1 
ATOM   2120 C CG  . ASN C 3 367 ? 244.875 204.600 173.957 1.00 66.85  ? 370 ASN R CG  1 
ATOM   2121 O OD1 . ASN C 3 367 ? 243.981 204.506 174.797 1.00 66.85  ? 370 ASN R OD1 1 
ATOM   2122 N ND2 . ASN C 3 367 ? 245.345 205.769 173.542 1.00 66.85  ? 370 ASN R ND2 1 
ATOM   2123 N N   . SER C 3 368 ? 245.391 202.088 169.847 1.00 59.62  ? 371 SER R N   1 
ATOM   2124 C CA  . SER C 3 368 ? 246.206 201.448 168.827 1.00 59.62  ? 371 SER R CA  1 
ATOM   2125 C C   . SER C 3 368 ? 246.051 202.254 167.549 1.00 59.62  ? 371 SER R C   1 
ATOM   2126 O O   . SER C 3 368 ? 244.933 202.630 167.187 1.00 59.62  ? 371 SER R O   1 
ATOM   2127 C CB  . SER C 3 368 ? 245.789 199.994 168.602 1.00 59.62  ? 371 SER R CB  1 
ATOM   2128 O OG  . SER C 3 368 ? 246.486 199.435 167.504 1.00 59.62  ? 371 SER R OG  1 
ATOM   2129 N N   . ALA C 3 369 ? 247.164 202.519 166.874 1.00 53.39  ? 372 ALA R N   1 
ATOM   2130 C CA  . ALA C 3 369 ? 247.136 203.377 165.699 1.00 53.39  ? 372 ALA R CA  1 
ATOM   2131 C C   . ALA C 3 369 ? 246.724 202.641 164.433 1.00 53.39  ? 372 ALA R C   1 
ATOM   2132 O O   . ALA C 3 369 ? 246.663 203.264 163.368 1.00 53.39  ? 372 ALA R O   1 
ATOM   2133 C CB  . ALA C 3 369 ? 248.503 204.031 165.494 1.00 53.39  ? 372 ALA R CB  1 
ATOM   2134 N N   . SER C 3 370 ? 246.450 201.338 164.517 1.00 47.09  ? 373 SER R N   1 
ATOM   2135 C CA  . SER C 3 370 ? 246.055 200.590 163.328 1.00 47.09  ? 373 SER R CA  1 
ATOM   2136 C C   . SER C 3 370 ? 244.623 200.904 162.912 1.00 47.09  ? 373 SER R C   1 
ATOM   2137 O O   . SER C 3 370 ? 244.344 201.078 161.722 1.00 47.09  ? 373 SER R O   1 
ATOM   2138 C CB  . SER C 3 370 ? 246.219 199.095 163.576 1.00 47.09  ? 373 SER R CB  1 
ATOM   2139 O OG  . SER C 3 370 ? 245.937 198.363 162.401 1.00 47.09  ? 373 SER R OG  1 
ATOM   2140 N N   . PHE C 3 371 ? 243.707 200.994 163.875 1.00 38.17  ? 374 PHE R N   1 
ATOM   2141 C CA  . PHE C 3 371 ? 242.283 201.124 163.578 1.00 38.17  ? 374 PHE R CA  1 
ATOM   2142 C C   . PHE C 3 371 ? 242.006 202.483 162.957 1.00 38.17  ? 374 PHE R C   1 
ATOM   2143 O O   . PHE C 3 371 ? 241.980 203.500 163.653 1.00 38.17  ? 374 PHE R O   1 
ATOM   2144 C CB  . PHE C 3 371 ? 241.460 200.930 164.846 1.00 38.17  ? 374 PHE R CB  1 
ATOM   2145 C CG  . PHE C 3 371 ? 241.754 199.647 165.562 1.00 38.17  ? 374 PHE R CG  1 
ATOM   2146 C CD1 . PHE C 3 371 ? 242.180 198.536 164.867 1.00 38.17  ? 374 PHE R CD1 1 
ATOM   2147 C CD2 . PHE C 3 371 ? 241.614 199.554 166.927 1.00 38.17  ? 374 PHE R CD2 1 
ATOM   2148 C CE1 . PHE C 3 371 ? 242.458 197.363 165.519 1.00 38.17  ? 374 PHE R CE1 1 
ATOM   2149 C CE2 . PHE C 3 371 ? 241.891 198.380 167.580 1.00 38.17  ? 374 PHE R CE2 1 
ATOM   2150 C CZ  . PHE C 3 371 ? 242.311 197.286 166.875 1.00 38.17  ? 374 PHE R CZ  1 
ATOM   2151 N N   . SER C 3 372 ? 241.777 202.498 161.651 1.00 28.97  ? 375 SER R N   1 
ATOM   2152 C CA  . SER C 3 372 ? 241.534 203.720 160.905 1.00 28.97  ? 375 SER R CA  1 
ATOM   2153 C C   . SER C 3 372 ? 240.126 204.257 161.082 1.00 28.97  ? 375 SER R C   1 
ATOM   2154 O O   . SER C 3 372 ? 239.686 205.069 160.261 1.00 28.97  ? 375 SER R O   1 
ATOM   2155 C CB  . SER C 3 372 ? 241.813 203.490 159.423 1.00 28.97  ? 375 SER R CB  1 
ATOM   2156 O OG  . SER C 3 372 ? 241.256 204.534 158.652 1.00 28.97  ? 375 SER R OG  1 
ATOM   2157 N N   . THR C 3 373 ? 239.406 203.810 162.109 1.00 30.68  ? 376 THR R N   1 
ATOM   2158 C CA  . THR C 3 373 ? 238.085 204.333 162.436 1.00 30.68  ? 376 THR R CA  1 
ATOM   2159 C C   . THR C 3 373 ? 237.662 203.851 163.817 1.00 30.68  ? 376 THR R C   1 
ATOM   2160 O O   . THR C 3 373 ? 237.754 202.659 164.116 1.00 30.68  ? 376 THR R O   1 
ATOM   2161 C CB  . THR C 3 373 ? 237.054 203.914 161.388 1.00 30.68  ? 376 THR R CB  1 
ATOM   2162 O OG1 . THR C 3 373 ? 237.348 204.561 160.145 1.00 30.68  ? 376 THR R OG1 1 
ATOM   2163 C CG2 . THR C 3 373 ? 235.665 204.303 161.828 1.00 30.68  ? 376 THR R CG2 1 
ATOM   2164 N N   . PHE C 3 374 ? 237.222 204.766 164.674 1.00 42.66  ? 377 PHE R N   1 
ATOM   2165 C CA  . PHE C 3 374 ? 236.708 204.391 165.988 1.00 42.66  ? 377 PHE R CA  1 
ATOM   2166 C C   . PHE C 3 374 ? 235.833 205.551 166.432 1.00 42.66  ? 377 PHE R C   1 
ATOM   2167 O O   . PHE C 3 374 ? 236.354 206.618 166.765 1.00 42.66  ? 377 PHE R O   1 
ATOM   2168 C CB  . PHE C 3 374 ? 237.838 204.158 166.978 1.00 42.66  ? 377 PHE R CB  1 
ATOM   2169 C CG  . PHE C 3 374 ? 237.414 203.456 168.231 1.00 42.66  ? 377 PHE R CG  1 
ATOM   2170 C CD1 . PHE C 3 374 ? 237.831 202.172 168.480 1.00 42.66  ? 377 PHE R CD1 1 
ATOM   2171 C CD2 . PHE C 3 374 ? 236.552 204.050 169.126 1.00 42.66  ? 377 PHE R CD2 1 
ATOM   2172 C CE1 . PHE C 3 374 ? 237.445 201.509 169.614 1.00 42.66  ? 377 PHE R CE1 1 
ATOM   2173 C CE2 . PHE C 3 374 ? 236.157 203.386 170.263 1.00 42.66  ? 377 PHE R CE2 1 
ATOM   2174 C CZ  . PHE C 3 374 ? 236.603 202.112 170.504 1.00 42.66  ? 377 PHE R CZ  1 
ATOM   2175 N N   . LYS C 3 375 ? 234.522 205.347 166.449 1.00 51.08  ? 378 LYS R N   1 
ATOM   2176 C CA  . LYS C 3 375 ? 233.609 206.448 166.718 1.00 51.08  ? 378 LYS R CA  1 
ATOM   2177 C C   . LYS C 3 375 ? 232.310 205.869 167.234 1.00 51.08  ? 378 LYS R C   1 
ATOM   2178 O O   . LYS C 3 375 ? 231.757 204.963 166.608 1.00 51.08  ? 378 LYS R O   1 
ATOM   2179 C CB  . LYS C 3 375 ? 233.355 207.269 165.454 1.00 51.08  ? 378 LYS R CB  1 
ATOM   2180 C CG  . LYS C 3 375 ? 233.126 206.430 164.219 1.00 51.08  ? 378 LYS R CG  1 
ATOM   2181 C CD  . LYS C 3 375 ? 232.463 207.249 163.136 1.00 51.08  ? 378 LYS R CD  1 
ATOM   2182 C CE  . LYS C 3 375 ? 233.334 208.426 162.733 1.00 51.08  ? 378 LYS R CE  1 
ATOM   2183 N NZ  . LYS C 3 375 ? 234.513 208.015 161.926 1.00 51.08  ? 378 LYS R NZ  1 
ATOM   2184 N N   . CYS C 3 376 ? 231.823 206.373 168.364 1.00 59.01  ? 379 CYS R N   1 
ATOM   2185 C CA  . CYS C 3 376 ? 230.685 205.693 168.956 1.00 59.01  ? 379 CYS R CA  1 
ATOM   2186 C C   . CYS C 3 376 ? 229.859 206.561 169.886 1.00 59.01  ? 379 CYS R C   1 
ATOM   2187 O O   . CYS C 3 376 ? 230.131 207.745 170.102 1.00 59.01  ? 379 CYS R O   1 
ATOM   2188 C CB  . CYS C 3 376 ? 231.142 204.397 169.587 1.00 59.01  ? 379 CYS R CB  1 
ATOM   2189 S SG  . CYS C 3 376 ? 232.291 204.190 170.955 1.00 59.01  ? 379 CYS R SG  1 
ATOM   2190 N N   . TYR C 3 377 ? 228.831 205.917 170.434 1.00 55.99  ? 380 TYR R N   1 
ATOM   2191 C CA  . TYR C 3 377 ? 227.518 206.500 170.633 1.00 55.99  ? 380 TYR R CA  1 
ATOM   2192 C C   . TYR C 3 377 ? 227.061 206.201 172.047 1.00 55.99  ? 380 TYR R C   1 
ATOM   2193 O O   . TYR C 3 377 ? 227.057 205.038 172.462 1.00 55.99  ? 380 TYR R O   1 
ATOM   2194 C CB  . TYR C 3 377 ? 226.527 205.886 169.643 1.00 55.99  ? 380 TYR R CB  1 
ATOM   2195 C CG  . TYR C 3 377 ? 226.971 205.954 168.202 1.00 55.99  ? 380 TYR R CG  1 
ATOM   2196 C CD1 . TYR C 3 377 ? 226.775 207.089 167.439 1.00 55.99  ? 380 TYR R CD1 1 
ATOM   2197 C CD2 . TYR C 3 377 ? 227.598 204.871 167.610 1.00 55.99  ? 380 TYR R CD2 1 
ATOM   2198 C CE1 . TYR C 3 377 ? 227.190 207.137 166.121 1.00 55.99  ? 380 TYR R CE1 1 
ATOM   2199 C CE2 . TYR C 3 377 ? 228.014 204.913 166.304 1.00 55.99  ? 380 TYR R CE2 1 
ATOM   2200 C CZ  . TYR C 3 377 ? 227.810 206.045 165.564 1.00 55.99  ? 380 TYR R CZ  1 
ATOM   2201 O OH  . TYR C 3 377 ? 228.228 206.085 164.258 1.00 55.99  ? 380 TYR R OH  1 
ATOM   2202 N N   . GLY C 3 378 ? 226.691 207.236 172.790 1.00 60.29  ? 381 GLY R N   1 
ATOM   2203 C CA  . GLY C 3 378 ? 226.147 207.036 174.117 1.00 60.29  ? 381 GLY R CA  1 
ATOM   2204 C C   . GLY C 3 378 ? 227.131 206.434 175.096 1.00 60.29  ? 381 GLY R C   1 
ATOM   2205 O O   . GLY C 3 378 ? 226.860 206.373 176.297 1.00 60.29  ? 381 GLY R O   1 
ATOM   2206 N N   . VAL C 3 379 ? 228.273 205.969 174.593 1.00 60.53  ? 382 VAL R N   1 
ATOM   2207 C CA  . VAL C 3 379 ? 229.351 205.461 175.429 1.00 60.53  ? 382 VAL R CA  1 
ATOM   2208 C C   . VAL C 3 379 ? 230.666 206.011 174.897 1.00 60.53  ? 382 VAL R C   1 
ATOM   2209 O O   . VAL C 3 379 ? 231.229 205.479 173.934 1.00 60.53  ? 382 VAL R O   1 
ATOM   2210 C CB  . VAL C 3 379 ? 229.367 203.923 175.462 1.00 60.53  ? 382 VAL R CB  1 
ATOM   2211 C CG1 . VAL C 3 379 ? 230.516 203.435 176.312 1.00 60.53  ? 382 VAL R CG1 1 
ATOM   2212 C CG2 . VAL C 3 379 ? 228.054 203.385 175.994 1.00 60.53  ? 382 VAL R CG2 1 
ATOM   2213 N N   . SER C 3 380 ? 231.159 207.080 175.514 1.00 66.87  ? 383 SER R N   1 
ATOM   2214 C CA  . SER C 3 380 ? 232.389 207.700 175.051 1.00 66.87  ? 383 SER R CA  1 
ATOM   2215 C C   . SER C 3 380 ? 233.568 206.758 175.280 1.00 66.87  ? 383 SER R C   1 
ATOM   2216 O O   . SER C 3 380 ? 233.621 206.069 176.302 1.00 66.87  ? 383 SER R O   1 
ATOM   2217 C CB  . SER C 3 380 ? 232.626 209.022 175.773 1.00 66.87  ? 383 SER R CB  1 
ATOM   2218 O OG  . SER C 3 380 ? 233.963 209.457 175.609 1.00 66.87  ? 383 SER R OG  1 
ATOM   2219 N N   . PRO C 3 381 ? 234.531 206.712 174.357 1.00 67.01  ? 384 PRO R N   1 
ATOM   2220 C CA  . PRO C 3 381 ? 235.598 205.705 174.461 1.00 67.01  ? 384 PRO R CA  1 
ATOM   2221 C C   . PRO C 3 381 ? 236.436 205.819 175.717 1.00 67.01  ? 384 PRO R C   1 
ATOM   2222 O O   . PRO C 3 381 ? 237.048 204.824 176.123 1.00 67.01  ? 384 PRO R O   1 
ATOM   2223 C CB  . PRO C 3 381 ? 236.441 205.953 173.202 1.00 67.01  ? 384 PRO R CB  1 
ATOM   2224 C CG  . PRO C 3 381 ? 236.105 207.331 172.771 1.00 67.01  ? 384 PRO R CG  1 
ATOM   2225 C CD  . PRO C 3 381 ? 234.676 207.542 173.151 1.00 67.01  ? 384 PRO R CD  1 
ATOM   2226 N N   . THR C 3 382 ? 236.490 206.992 176.347 1.00 66.10  ? 385 THR R N   1 
ATOM   2227 C CA  . THR C 3 382 ? 237.333 207.150 177.525 1.00 66.10  ? 385 THR R CA  1 
ATOM   2228 C C   . THR C 3 382 ? 236.826 206.317 178.696 1.00 66.10  ? 385 THR R C   1 
ATOM   2229 O O   . THR C 3 382 ? 237.624 205.728 179.434 1.00 66.10  ? 385 THR R O   1 
ATOM   2230 C CB  . THR C 3 382 ? 237.416 208.623 177.913 1.00 66.10  ? 385 THR R CB  1 
ATOM   2231 O OG1 . THR C 3 382 ? 236.190 209.020 178.540 1.00 66.10  ? 385 THR R OG1 1 
ATOM   2232 C CG2 . THR C 3 382 ? 237.649 209.477 176.680 1.00 66.10  ? 385 THR R CG2 1 
ATOM   2233 N N   . LYS C 3 383 ? 235.508 206.252 178.884 1.00 70.44  ? 386 LYS R N   1 
ATOM   2234 C CA  . LYS C 3 383 ? 234.912 205.580 180.033 1.00 70.44  ? 386 LYS R CA  1 
ATOM   2235 C C   . LYS C 3 383 ? 234.358 204.203 179.684 1.00 70.44  ? 386 LYS R C   1 
ATOM   2236 O O   . LYS C 3 383 ? 233.366 203.766 180.276 1.00 70.44  ? 386 LYS R O   1 
ATOM   2237 C CB  . LYS C 3 383 ? 233.813 206.449 180.638 1.00 70.44  ? 386 LYS R CB  1 
ATOM   2238 C CG  . LYS C 3 383 ? 234.268 207.842 181.018 1.00 70.44  ? 386 LYS R CG  1 
ATOM   2239 C CD  . LYS C 3 383 ? 233.092 208.707 181.432 1.00 70.44  ? 386 LYS R CD  1 
ATOM   2240 C CE  . LYS C 3 383 ? 233.263 209.227 182.849 1.00 70.44  ? 386 LYS R CE  1 
ATOM   2241 N NZ  . LYS C 3 383 ? 232.364 210.379 183.127 1.00 70.44  ? 386 LYS R NZ  1 
ATOM   2242 N N   . LEU C 3 384 ? 234.976 203.511 178.726 1.00 71.96  ? 387 LEU R N   1 
ATOM   2243 C CA  . LEU C 3 384 ? 234.472 202.205 178.317 1.00 71.96  ? 387 LEU R CA  1 
ATOM   2244 C C   . LEU C 3 384 ? 234.618 201.178 179.431 1.00 71.96  ? 387 LEU R C   1 
ATOM   2245 O O   . LEU C 3 384 ? 233.650 200.503 179.798 1.00 71.96  ? 387 LEU R O   1 
ATOM   2246 C CB  . LEU C 3 384 ? 235.208 201.730 177.067 1.00 71.96  ? 387 LEU R CB  1 
ATOM   2247 C CG  . LEU C 3 384 ? 234.803 202.341 175.731 1.00 71.96  ? 387 LEU R CG  1 
ATOM   2248 C CD1 . LEU C 3 384 ? 235.897 202.107 174.710 1.00 71.96  ? 387 LEU R CD1 1 
ATOM   2249 C CD2 . LEU C 3 384 ? 233.497 201.742 175.256 1.00 71.96  ? 387 LEU R CD2 1 
ATOM   2250 N N   . ASN C 3 385 ? 235.817 201.060 179.995 1.00 74.19  ? 388 ASN R N   1 
ATOM   2251 C CA  . ASN C 3 385 ? 236.130 199.962 180.899 1.00 74.19  ? 388 ASN R CA  1 
ATOM   2252 C C   . ASN C 3 385 ? 235.570 200.155 182.298 1.00 74.19  ? 388 ASN R C   1 
ATOM   2253 O O   . ASN C 3 385 ? 235.605 199.212 183.095 1.00 74.19  ? 388 ASN R O   1 
ATOM   2254 C CB  . ASN C 3 385 ? 237.644 199.766 180.975 1.00 74.19  ? 388 ASN R CB  1 
ATOM   2255 C CG  . ASN C 3 385 ? 238.380 201.060 181.204 1.00 74.19  ? 388 ASN R CG  1 
ATOM   2256 O OD1 . ASN C 3 385 ? 237.768 202.119 181.326 1.00 74.19  ? 388 ASN R OD1 1 
ATOM   2257 N ND2 . ASN C 3 385 ? 239.702 200.985 181.264 1.00 74.19  ? 388 ASN R ND2 1 
ATOM   2258 N N   . ASP C 3 386 ? 235.050 201.334 182.614 1.00 75.08  ? 389 ASP R N   1 
ATOM   2259 C CA  . ASP C 3 386 ? 234.535 201.615 183.943 1.00 75.08  ? 389 ASP R CA  1 
ATOM   2260 C C   . ASP C 3 386 ? 233.053 201.296 184.083 1.00 75.08  ? 389 ASP R C   1 
ATOM   2261 O O   . ASP C 3 386 ? 232.472 201.567 185.137 1.00 75.08  ? 389 ASP R O   1 
ATOM   2262 C CB  . ASP C 3 386 ? 234.800 203.077 184.299 1.00 75.08  ? 389 ASP R CB  1 
ATOM   2263 C CG  . ASP C 3 386 ? 236.270 203.429 184.209 1.00 75.08  ? 389 ASP R CG  1 
ATOM   2264 O OD1 . ASP C 3 386 ? 237.090 202.498 184.071 1.00 75.08  ? 389 ASP R OD1 1 
ATOM   2265 O OD2 . ASP C 3 386 ? 236.606 204.629 184.275 1.00 75.08  ? 389 ASP R OD2 1 
ATOM   2266 N N   . LEU C 3 387 ? 232.433 200.732 183.051 1.00 72.23  ? 390 LEU R N   1 
ATOM   2267 C CA  . LEU C 3 387 ? 231.068 200.237 183.120 1.00 72.23  ? 390 LEU R CA  1 
ATOM   2268 C C   . LEU C 3 387 ? 231.039 198.779 182.690 1.00 72.23  ? 390 LEU R C   1 
ATOM   2269 O O   . LEU C 3 387 ? 231.837 198.347 181.852 1.00 72.23  ? 390 LEU R O   1 
ATOM   2270 C CB  . LEU C 3 387 ? 230.126 201.053 182.234 1.00 72.23  ? 390 LEU R CB  1 
ATOM   2271 C CG  . LEU C 3 387 ? 229.843 202.485 182.674 1.00 72.23  ? 390 LEU R CG  1 
ATOM   2272 C CD1 . LEU C 3 387 ? 229.369 203.317 181.497 1.00 72.23  ? 390 LEU R CD1 1 
ATOM   2273 C CD2 . LEU C 3 387 ? 228.810 202.487 183.781 1.00 72.23  ? 390 LEU R CD2 1 
ATOM   2274 N N   . CYS C 3 388 ? 230.116 198.020 183.270 1.00 60.55  ? 391 CYS R N   1 
ATOM   2275 C CA  . CYS C 3 388 ? 229.951 196.612 182.947 1.00 60.55  ? 391 CYS R CA  1 
ATOM   2276 C C   . CYS C 3 388 ? 228.513 196.337 182.534 1.00 60.55  ? 391 CYS R C   1 
ATOM   2277 O O   . CYS C 3 388 ? 227.571 196.850 183.145 1.00 60.55  ? 391 CYS R O   1 
ATOM   2278 C CB  . CYS C 3 388 ? 230.342 195.719 184.127 1.00 60.55  ? 391 CYS R CB  1 
ATOM   2279 S SG  . CYS C 3 388 ? 232.128 195.548 184.377 1.00 60.55  ? 391 CYS R SG  1 
ATOM   2280 N N   . PHE C 3 389 ? 228.356 195.529 181.492 1.00 57.64  ? 392 PHE R N   1 
ATOM   2281 C CA  . PHE C 3 389 ? 227.060 195.146 180.959 1.00 57.64  ? 392 PHE R CA  1 
ATOM   2282 C C   . PHE C 3 389 ? 226.837 193.655 181.172 1.00 57.64  ? 392 PHE R C   1 
ATOM   2283 O O   . PHE C 3 389 ? 227.689 192.944 181.709 1.00 57.64  ? 392 PHE R O   1 
ATOM   2284 C CB  . PHE C 3 389 ? 226.953 195.483 179.470 1.00 57.64  ? 392 PHE R CB  1 
ATOM   2285 C CG  . PHE C 3 389 ? 227.476 196.839 179.116 1.00 57.64  ? 392 PHE R CG  1 
ATOM   2286 C CD1 . PHE C 3 389 ? 226.725 197.972 179.371 1.00 57.64  ? 392 PHE R CD1 1 
ATOM   2287 C CD2 . PHE C 3 389 ? 228.711 196.983 178.516 1.00 57.64  ? 392 PHE R CD2 1 
ATOM   2288 C CE1 . PHE C 3 389 ? 227.200 199.222 179.038 1.00 57.64  ? 392 PHE R CE1 1 
ATOM   2289 C CE2 . PHE C 3 389 ? 229.190 198.229 178.181 1.00 57.64  ? 392 PHE R CE2 1 
ATOM   2290 C CZ  . PHE C 3 389 ? 228.435 199.350 178.445 1.00 57.64  ? 392 PHE R CZ  1 
ATOM   2291 N N   . THR C 3 390 ? 225.665 193.184 180.741 1.00 51.77  ? 393 THR R N   1 
ATOM   2292 C CA  . THR C 3 390 ? 225.341 191.770 180.889 1.00 51.77  ? 393 THR R CA  1 
ATOM   2293 C C   . THR C 3 390 ? 225.923 190.940 179.751 1.00 51.77  ? 393 THR R C   1 
ATOM   2294 O O   . THR C 3 390 ? 226.523 189.887 179.990 1.00 51.77  ? 393 THR R O   1 
ATOM   2295 C CB  . THR C 3 390 ? 223.832 191.585 180.961 1.00 51.77  ? 393 THR R CB  1 
ATOM   2296 O OG1 . THR C 3 390 ? 223.328 192.259 182.118 1.00 51.77  ? 393 THR R OG1 1 
ATOM   2297 C CG2 . THR C 3 390 ? 223.489 190.117 181.051 1.00 51.77  ? 393 THR R CG2 1 
ATOM   2298 N N   . ASN C 3 391 ? 225.755 191.389 178.511 1.00 52.65  ? 394 ASN R N   1 
ATOM   2299 C CA  . ASN C 3 391 ? 226.315 190.672 177.377 1.00 52.65  ? 394 ASN R CA  1 
ATOM   2300 C C   . ASN C 3 391 ? 226.840 191.669 176.357 1.00 52.65  ? 394 ASN R C   1 
ATOM   2301 O O   . ASN C 3 391 ? 226.261 192.739 176.157 1.00 52.65  ? 394 ASN R O   1 
ATOM   2302 C CB  . ASN C 3 391 ? 225.285 189.741 176.730 1.00 52.65  ? 394 ASN R CB  1 
ATOM   2303 C CG  . ASN C 3 391 ? 223.986 190.443 176.406 1.00 52.65  ? 394 ASN R CG  1 
ATOM   2304 O OD1 . ASN C 3 391 ? 223.862 191.655 176.563 1.00 52.65  ? 394 ASN R OD1 1 
ATOM   2305 N ND2 . ASN C 3 391 ? 223.006 189.680 175.939 1.00 52.65  ? 394 ASN R ND2 1 
ATOM   2306 N N   . VAL C 3 392 ? 227.946 191.306 175.716 1.00 47.47  ? 395 VAL R N   1 
ATOM   2307 C CA  . VAL C 3 392 ? 228.574 192.121 174.688 1.00 47.47  ? 395 VAL R CA  1 
ATOM   2308 C C   . VAL C 3 392 ? 228.692 191.279 173.431 1.00 47.47  ? 395 VAL R C   1 
ATOM   2309 O O   . VAL C 3 392 ? 229.250 190.179 173.474 1.00 47.47  ? 395 VAL R O   1 
ATOM   2310 C CB  . VAL C 3 392 ? 229.958 192.623 175.129 1.00 47.47  ? 395 VAL R CB  1 
ATOM   2311 C CG1 . VAL C 3 392 ? 230.552 193.513 174.075 1.00 47.47  ? 395 VAL R CG1 1 
ATOM   2312 C CG2 . VAL C 3 392 ? 229.853 193.361 176.435 1.00 47.47  ? 395 VAL R CG2 1 
ATOM   2313 N N   . TYR C 3 393 ? 228.176 191.788 172.321 1.00 42.00  ? 396 TYR R N   1 
ATOM   2314 C CA  . TYR C 3 393 ? 228.215 191.084 171.050 1.00 42.00  ? 396 TYR R CA  1 
ATOM   2315 C C   . TYR C 3 393 ? 229.292 191.666 170.142 1.00 42.00  ? 396 TYR R C   1 
ATOM   2316 O O   . TYR C 3 393 ? 229.756 192.788 170.334 1.00 42.00  ? 396 TYR R O   1 
ATOM   2317 C CB  . TYR C 3 393 ? 226.860 191.159 170.352 1.00 42.00  ? 396 TYR R CB  1 
ATOM   2318 C CG  . TYR C 3 393 ? 225.738 190.477 171.087 1.00 42.00  ? 396 TYR R CG  1 
ATOM   2319 C CD1 . TYR C 3 393 ? 225.819 189.142 171.427 1.00 42.00  ? 396 TYR R CD1 1 
ATOM   2320 C CD2 . TYR C 3 393 ? 224.582 191.164 171.409 1.00 42.00  ? 396 TYR R CD2 1 
ATOM   2321 C CE1 . TYR C 3 393 ? 224.792 188.514 172.084 1.00 42.00  ? 396 TYR R CE1 1 
ATOM   2322 C CE2 . TYR C 3 393 ? 223.550 190.546 172.067 1.00 42.00  ? 396 TYR R CE2 1 
ATOM   2323 C CZ  . TYR C 3 393 ? 223.660 189.219 172.403 1.00 42.00  ? 396 TYR R CZ  1 
ATOM   2324 O OH  . TYR C 3 393 ? 222.631 188.593 173.063 1.00 42.00  ? 396 TYR R OH  1 
ATOM   2325 N N   . ALA C 3 394 ? 229.682 190.891 169.134 1.00 30.67  ? 397 ALA R N   1 
ATOM   2326 C CA  . ALA C 3 394 ? 230.725 191.313 168.205 1.00 30.67  ? 397 ALA R CA  1 
ATOM   2327 C C   . ALA C 3 394 ? 230.365 190.838 166.807 1.00 30.67  ? 397 ALA R C   1 
ATOM   2328 O O   . ALA C 3 394 ? 230.440 189.642 166.520 1.00 30.67  ? 397 ALA R O   1 
ATOM   2329 C CB  . ALA C 3 394 ? 232.085 190.768 168.629 1.00 30.67  ? 397 ALA R CB  1 
ATOM   2330 N N   . ASP C 3 395 ? 230.002 191.769 165.933 1.00 26.57  ? 398 ASP R N   1 
ATOM   2331 C CA  . ASP C 3 395 ? 229.587 191.458 164.572 1.00 26.57  ? 398 ASP R CA  1 
ATOM   2332 C C   . ASP C 3 395 ? 230.718 191.814 163.617 1.00 26.57  ? 398 ASP R C   1 
ATOM   2333 O O   . ASP C 3 395 ? 231.080 192.986 163.500 1.00 26.57  ? 398 ASP R O   1 
ATOM   2334 C CB  . ASP C 3 395 ? 228.331 192.244 164.214 1.00 26.57  ? 398 ASP R CB  1 
ATOM   2335 C CG  . ASP C 3 395 ? 227.208 192.018 165.194 1.00 26.57  ? 398 ASP R CG  1 
ATOM   2336 O OD1 . ASP C 3 395 ? 227.156 190.934 165.799 1.00 26.57  ? 398 ASP R OD1 1 
ATOM   2337 O OD2 . ASP C 3 395 ? 226.377 192.931 165.369 1.00 26.57  ? 398 ASP R OD2 1 
ATOM   2338 N N   . SER C 3 396 ? 231.257 190.822 162.918 1.00 28.14  ? 399 SER R N   1 
ATOM   2339 C CA  . SER C 3 396 ? 232.439 191.019 162.094 1.00 28.14  ? 399 SER R CA  1 
ATOM   2340 C C   . SER C 3 396 ? 232.172 190.636 160.648 1.00 28.14  ? 399 SER R C   1 
ATOM   2341 O O   . SER C 3 396 ? 231.527 189.624 160.382 1.00 28.14  ? 399 SER R O   1 
ATOM   2342 C CB  . SER C 3 396 ? 233.591 190.196 162.622 1.00 28.14  ? 399 SER R CB  1 
ATOM   2343 O OG  . SER C 3 396 ? 233.150 188.902 162.963 1.00 28.14  ? 399 SER R OG  1 
ATOM   2344 N N   . PHE C 3 397 ? 232.688 191.430 159.716 1.00 22.64  ? 400 PHE R N   1 
ATOM   2345 C CA  . PHE C 3 397 ? 232.549 191.117 158.299 1.00 22.64  ? 400 PHE R CA  1 
ATOM   2346 C C   . PHE C 3 397 ? 233.644 191.840 157.518 1.00 22.64  ? 400 PHE R C   1 
ATOM   2347 O O   . PHE C 3 397 ? 234.647 192.265 158.099 1.00 22.64  ? 400 PHE R O   1 
ATOM   2348 C CB  . PHE C 3 397 ? 231.140 191.466 157.807 1.00 22.64  ? 400 PHE R CB  1 
ATOM   2349 C CG  . PHE C 3 397 ? 230.632 192.763 158.302 1.00 22.64  ? 400 PHE R CG  1 
ATOM   2350 C CD1 . PHE C 3 397 ? 230.846 193.907 157.592 1.00 22.64  ? 400 PHE R CD1 1 
ATOM   2351 C CD2 . PHE C 3 397 ? 229.916 192.833 159.467 1.00 22.64  ? 400 PHE R CD2 1 
ATOM   2352 C CE1 . PHE C 3 397 ? 230.368 195.097 158.036 1.00 22.64  ? 400 PHE R CE1 1 
ATOM   2353 C CE2 . PHE C 3 397 ? 229.436 194.020 159.914 1.00 22.64  ? 400 PHE R CE2 1 
ATOM   2354 C CZ  . PHE C 3 397 ? 229.662 195.155 159.198 1.00 22.64  ? 400 PHE R CZ  1 
ATOM   2355 N N   . VAL C 3 398 ? 233.481 191.931 156.199 1.00 46.07  ? 401 VAL R N   1 
ATOM   2356 C CA  . VAL C 3 398 ? 234.417 192.633 155.325 1.00 46.07  ? 401 VAL R CA  1 
ATOM   2357 C C   . VAL C 3 398 ? 233.677 193.356 154.214 1.00 46.07  ? 401 VAL R C   1 
ATOM   2358 O O   . VAL C 3 398 ? 232.944 192.736 153.441 1.00 46.07  ? 401 VAL R O   1 
ATOM   2359 C CB  . VAL C 3 398 ? 235.440 191.676 154.709 1.00 46.07  ? 401 VAL R CB  1 
ATOM   2360 C CG1 . VAL C 3 398 ? 236.161 192.370 153.603 1.00 46.07  ? 401 VAL R CG1 1 
ATOM   2361 C CG2 . VAL C 3 398 ? 236.421 191.251 155.732 1.00 46.07  ? 401 VAL R CG2 1 
ATOM   2362 N N   . ILE C 3 399 ? 233.896 194.661 154.090 1.00 38.13  ? 402 ILE R N   1 
ATOM   2363 C CA  . ILE C 3 399 ? 233.155 195.489 153.154 1.00 38.13  ? 402 ILE R CA  1 
ATOM   2364 C C   . ILE C 3 399 ? 234.118 196.366 152.371 1.00 38.13  ? 402 ILE R C   1 
ATOM   2365 O O   . ILE C 3 399 ? 235.305 196.457 152.675 1.00 38.13  ? 402 ILE R O   1 
ATOM   2366 C CB  . ILE C 3 399 ? 232.107 196.359 153.859 1.00 38.13  ? 402 ILE R CB  1 
ATOM   2367 C CG1 . ILE C 3 399 ? 232.788 197.305 154.820 1.00 38.13  ? 402 ILE R CG1 1 
ATOM   2368 C CG2 . ILE C 3 399 ? 231.143 195.519 154.618 1.00 38.13  ? 402 ILE R CG2 1 
ATOM   2369 C CD1 . ILE C 3 399 ? 231.860 198.315 155.362 1.00 38.13  ? 402 ILE R CD1 1 
ATOM   2370 N N   . ARG C 3 400 ? 233.578 197.014 151.347 1.00 43.48  ? 403 ARG R N   1 
ATOM   2371 C CA  . ARG C 3 400 ? 234.360 197.894 150.497 1.00 43.48  ? 403 ARG R CA  1 
ATOM   2372 C C   . ARG C 3 400 ? 234.826 199.109 151.286 1.00 43.48  ? 403 ARG R C   1 
ATOM   2373 O O   . ARG C 3 400 ? 234.167 199.553 152.226 1.00 43.48  ? 403 ARG R O   1 
ATOM   2374 C CB  . ARG C 3 400 ? 233.527 198.327 149.295 1.00 43.48  ? 403 ARG R CB  1 
ATOM   2375 C CG  . ARG C 3 400 ? 234.311 198.967 148.190 1.00 43.48  ? 403 ARG R CG  1 
ATOM   2376 C CD  . ARG C 3 400 ? 233.400 199.754 147.290 1.00 43.48  ? 403 ARG R CD  1 
ATOM   2377 N NE  . ARG C 3 400 ? 232.182 199.025 146.980 1.00 43.48  ? 403 ARG R NE  1 
ATOM   2378 C CZ  . ARG C 3 400 ? 231.222 199.501 146.198 1.00 43.48  ? 403 ARG R CZ  1 
ATOM   2379 N NH1 . ARG C 3 400 ? 231.347 200.704 145.658 1.00 43.48  ? 403 ARG R NH1 1 
ATOM   2380 N NH2 . ARG C 3 400 ? 230.137 198.780 145.956 1.00 43.48  ? 403 ARG R NH2 1 
ATOM   2381 N N   . GLY C 3 401 ? 235.980 199.650 150.898 1.00 42.93  ? 404 GLY R N   1 
ATOM   2382 C CA  . GLY C 3 401 ? 236.563 200.739 151.666 1.00 42.93  ? 404 GLY R CA  1 
ATOM   2383 C C   . GLY C 3 401 ? 235.694 201.980 151.693 1.00 42.93  ? 404 GLY R C   1 
ATOM   2384 O O   . GLY C 3 401 ? 235.460 202.566 152.750 1.00 42.93  ? 404 GLY R O   1 
ATOM   2385 N N   . ASP C 3 402 ? 235.200 202.396 150.528 1.00 46.85  ? 405 ASP R N   1 
ATOM   2386 C CA  . ASP C 3 402 ? 234.357 203.583 150.460 1.00 46.85  ? 405 ASP R CA  1 
ATOM   2387 C C   . ASP C 3 402 ? 233.068 203.355 151.232 1.00 46.85  ? 405 ASP R C   1 
ATOM   2388 O O   . ASP C 3 402 ? 232.591 204.248 151.938 1.00 46.85  ? 405 ASP R O   1 
ATOM   2389 C CB  . ASP C 3 402 ? 234.103 203.913 148.980 1.00 46.85  ? 405 ASP R CB  1 
ATOM   2390 C CG  . ASP C 3 402 ? 232.972 204.920 148.733 1.00 46.85  ? 405 ASP R CG  1 
ATOM   2391 O OD1 . ASP C 3 402 ? 232.880 205.377 147.575 1.00 46.85  ? 405 ASP R OD1 1 
ATOM   2392 O OD2 . ASP C 3 402 ? 232.202 205.303 149.632 1.00 46.85  ? 405 ASP R OD2 1 
ATOM   2393 N N   . GLU C 3 403 ? 232.539 202.146 151.159 1.00 45.25  ? 406 GLU R N   1 
ATOM   2394 C CA  . GLU C 3 403 ? 231.204 201.784 151.607 1.00 45.25  ? 406 GLU R CA  1 
ATOM   2395 C C   . GLU C 3 403 ? 231.068 201.767 153.123 1.00 45.25  ? 406 GLU R C   1 
ATOM   2396 O O   . GLU C 3 403 ? 229.948 201.650 153.623 1.00 45.25  ? 406 GLU R O   1 
ATOM   2397 C CB  . GLU C 3 403 ? 230.878 200.420 150.997 1.00 45.25  ? 406 GLU R CB  1 
ATOM   2398 C CG  . GLU C 3 403 ? 229.460 199.927 151.034 1.00 45.25  ? 406 GLU R CG  1 
ATOM   2399 C CD  . GLU C 3 403 ? 229.301 198.729 150.108 1.00 45.25  ? 406 GLU R CD  1 
ATOM   2400 O OE1 . GLU C 3 403 ? 230.053 198.653 149.115 1.00 45.25  ? 406 GLU R OE1 1 
ATOM   2401 O OE2 . GLU C 3 403 ? 228.433 197.874 150.344 1.00 45.25  ? 406 GLU R OE2 1 
ATOM   2402 N N   . VAL C 3 404 ? 232.171 201.912 153.864 1.00 42.71  ? 407 VAL R N   1 
ATOM   2403 C CA  . VAL C 3 404 ? 232.149 201.802 155.320 1.00 42.71  ? 407 VAL R CA  1 
ATOM   2404 C C   . VAL C 3 404 ? 231.436 202.960 155.995 1.00 42.71  ? 407 VAL R C   1 
ATOM   2405 O O   . VAL C 3 404 ? 231.202 202.912 157.204 1.00 42.71  ? 407 VAL R O   1 
ATOM   2406 C CB  . VAL C 3 404 ? 233.586 201.701 155.870 1.00 42.71  ? 407 VAL R CB  1 
ATOM   2407 C CG1 . VAL C 3 404 ? 234.259 203.054 155.832 1.00 42.71  ? 407 VAL R CG1 1 
ATOM   2408 C CG2 . VAL C 3 404 ? 233.601 201.119 157.269 1.00 42.71  ? 407 VAL R CG2 1 
ATOM   2409 N N   . ARG C 3 405 ? 231.080 204.004 155.255 1.00 46.43  ? 408 ARG R N   1 
ATOM   2410 C CA  . ARG C 3 405 ? 230.366 205.109 155.871 1.00 46.43  ? 408 ARG R CA  1 
ATOM   2411 C C   . ARG C 3 405 ? 228.932 204.757 156.232 1.00 46.43  ? 408 ARG R C   1 
ATOM   2412 O O   . ARG C 3 405 ? 228.271 205.559 156.895 1.00 46.43  ? 408 ARG R O   1 
ATOM   2413 C CB  . ARG C 3 405 ? 230.376 206.323 154.949 1.00 46.43  ? 408 ARG R CB  1 
ATOM   2414 C CG  . ARG C 3 405 ? 229.986 206.010 153.526 1.00 46.43  ? 408 ARG R CG  1 
ATOM   2415 C CD  . ARG C 3 405 ? 229.395 207.225 152.844 1.00 46.43  ? 408 ARG R CD  1 
ATOM   2416 N NE  . ARG C 3 405 ? 230.377 208.293 152.690 1.00 46.43  ? 408 ARG R NE  1 
ATOM   2417 C CZ  . ARG C 3 405 ? 231.345 208.297 151.780 1.00 46.43  ? 408 ARG R CZ  1 
ATOM   2418 N NH1 . ARG C 3 405 ? 231.466 207.289 150.930 1.00 46.43  ? 408 ARG R NH1 1 
ATOM   2419 N NH2 . ARG C 3 405 ? 232.192 209.315 151.717 1.00 46.43  ? 408 ARG R NH2 1 
ATOM   2420 N N   . GLN C 3 406 ? 228.432 203.597 155.809 1.00 46.12  ? 409 GLN R N   1 
ATOM   2421 C CA  . GLN C 3 406 ? 227.050 203.228 156.079 1.00 46.12  ? 409 GLN R CA  1 
ATOM   2422 C C   . GLN C 3 406 ? 226.873 202.398 157.338 1.00 46.12  ? 409 GLN R C   1 
ATOM   2423 O O   . GLN C 3 406 ? 225.733 202.098 157.700 1.00 46.12  ? 409 GLN R O   1 
ATOM   2424 C CB  . GLN C 3 406 ? 226.455 202.463 154.899 1.00 46.12  ? 409 GLN R CB  1 
ATOM   2425 C CG  . GLN C 3 406 ? 226.301 203.300 153.658 1.00 46.12  ? 409 GLN R CG  1 
ATOM   2426 C CD  . GLN C 3 406 ? 225.558 202.583 152.562 1.00 46.12  ? 409 GLN R CD  1 
ATOM   2427 O OE1 . GLN C 3 406 ? 225.132 201.442 152.728 1.00 46.12  ? 409 GLN R OE1 1 
ATOM   2428 N NE2 . GLN C 3 406 ? 225.405 203.245 151.425 1.00 46.12  ? 409 GLN R NE2 1 
ATOM   2429 N N   . ILE C 3 407 ? 227.950 202.020 158.016 1.00 37.26  ? 410 ILE R N   1 
ATOM   2430 C CA  . ILE C 3 407 ? 227.831 201.261 159.267 1.00 37.26  ? 410 ILE R CA  1 
ATOM   2431 C C   . ILE C 3 407 ? 227.694 202.300 160.371 1.00 37.26  ? 410 ILE R C   1 
ATOM   2432 O O   . ILE C 3 407 ? 228.638 202.638 161.087 1.00 37.26  ? 410 ILE R O   1 
ATOM   2433 C CB  . ILE C 3 407 ? 229.008 200.316 159.483 1.00 37.26  ? 410 ILE R CB  1 
ATOM   2434 C CG1 . ILE C 3 407 ? 229.220 199.469 158.237 1.00 37.26  ? 410 ILE R CG1 1 
ATOM   2435 C CG2 . ILE C 3 407 ? 228.765 199.442 160.692 1.00 37.26  ? 410 ILE R CG2 1 
ATOM   2436 C CD1 . ILE C 3 407 ? 228.079 198.575 157.948 1.00 37.26  ? 410 ILE R CD1 1 
ATOM   2437 N N   . ALA C 3 408 ? 226.477 202.799 160.526 1.00 48.52  ? 411 ALA R N   1 
ATOM   2438 C CA  . ALA C 3 408 ? 226.141 203.816 161.510 1.00 48.52  ? 411 ALA R CA  1 
ATOM   2439 C C   . ALA C 3 408 ? 224.631 204.010 161.528 1.00 48.52  ? 411 ALA R C   1 
ATOM   2440 O O   . ALA C 3 408 ? 223.971 203.829 160.498 1.00 48.52  ? 411 ALA R O   1 
ATOM   2441 C CB  . ALA C 3 408 ? 226.852 205.135 161.199 1.00 48.52  ? 411 ALA R CB  1 
ATOM   2442 N N   . PRO C 3 409 ? 224.048 204.369 162.666 1.00 52.72  ? 412 PRO R N   1 
ATOM   2443 C CA  . PRO C 3 409 ? 222.599 204.565 162.715 1.00 52.72  ? 412 PRO R CA  1 
ATOM   2444 C C   . PRO C 3 409 ? 222.150 205.710 161.823 1.00 52.72  ? 412 PRO R C   1 
ATOM   2445 O O   . PRO C 3 409 ? 222.891 206.660 161.569 1.00 52.72  ? 412 PRO R O   1 
ATOM   2446 C CB  . PRO C 3 409 ? 222.332 204.874 164.191 1.00 52.72  ? 412 PRO R CB  1 
ATOM   2447 C CG  . PRO C 3 409 ? 223.642 205.282 164.740 1.00 52.72  ? 412 PRO R CG  1 
ATOM   2448 C CD  . PRO C 3 409 ? 224.660 204.502 163.992 1.00 52.72  ? 412 PRO R CD  1 
ATOM   2449 N N   . GLY C 3 410 ? 220.922 205.592 161.329 1.00 68.89  ? 413 GLY R N   1 
ATOM   2450 C CA  . GLY C 3 410 ? 220.299 206.627 160.538 1.00 68.89  ? 413 GLY R CA  1 
ATOM   2451 C C   . GLY C 3 410 ? 220.742 206.687 159.097 1.00 68.89  ? 413 GLY R C   1 
ATOM   2452 O O   . GLY C 3 410 ? 220.252 207.543 158.351 1.00 68.89  ? 413 GLY R O   1 
ATOM   2453 N N   . GLN C 3 411 ? 221.636 205.807 158.676 1.00 65.32  ? 414 GLN R N   1 
ATOM   2454 C CA  . GLN C 3 411 ? 222.202 205.862 157.341 1.00 65.32  ? 414 GLN R CA  1 
ATOM   2455 C C   . GLN C 3 411 ? 221.455 204.885 156.436 1.00 65.32  ? 414 GLN R C   1 
ATOM   2456 O O   . GLN C 3 411 ? 220.777 203.969 156.907 1.00 65.32  ? 414 GLN R O   1 
ATOM   2457 C CB  . GLN C 3 411 ? 223.696 205.539 157.404 1.00 65.32  ? 414 GLN R CB  1 
ATOM   2458 C CG  . GLN C 3 411 ? 224.428 205.644 156.096 1.00 65.32  ? 414 GLN R CG  1 
ATOM   2459 C CD  . GLN C 3 411 ? 224.393 207.049 155.544 1.00 65.32  ? 414 GLN R CD  1 
ATOM   2460 O OE1 . GLN C 3 411 ? 223.658 207.339 154.602 1.00 65.32  ? 414 GLN R OE1 1 
ATOM   2461 N NE2 . GLN C 3 411 ? 225.191 207.933 156.129 1.00 65.32  ? 414 GLN R NE2 1 
ATOM   2462 N N   . THR C 3 412 ? 221.571 205.097 155.125 1.00 69.52  ? 415 THR R N   1 
ATOM   2463 C CA  . THR C 3 412 ? 220.844 204.289 154.153 1.00 69.52  ? 415 THR R CA  1 
ATOM   2464 C C   . THR C 3 412 ? 221.692 204.104 152.901 1.00 69.52  ? 415 THR R C   1 
ATOM   2465 O O   . THR C 3 412 ? 222.443 205.002 152.514 1.00 69.52  ? 415 THR R O   1 
ATOM   2466 C CB  . THR C 3 412 ? 219.499 204.940 153.804 1.00 69.52  ? 415 THR R CB  1 
ATOM   2467 O OG1 . THR C 3 412 ? 218.708 205.059 154.993 1.00 69.52  ? 415 THR R OG1 1 
ATOM   2468 C CG2 . THR C 3 412 ? 218.734 204.114 152.781 1.00 69.52  ? 415 THR R CG2 1 
ATOM   2469 N N   . GLY C 3 413 ? 221.567 202.934 152.276 1.00 62.24  ? 416 GLY R N   1 
ATOM   2470 C CA  . GLY C 3 413 ? 222.308 202.619 151.069 1.00 62.24  ? 416 GLY R CA  1 
ATOM   2471 C C   . GLY C 3 413 ? 222.166 201.171 150.644 1.00 62.24  ? 416 GLY R C   1 
ATOM   2472 O O   . GLY C 3 413 ? 221.049 200.656 150.547 1.00 62.24  ? 416 GLY R O   1 
ATOM   2473 N N   . ASN C 3 414 ? 223.285 200.505 150.365 1.00 53.71  ? 417 ASN R N   1 
ATOM   2474 C CA  . ASN C 3 414 ? 223.259 199.077 150.069 1.00 53.71  ? 417 ASN R CA  1 
ATOM   2475 C C   . ASN C 3 414 ? 223.411 198.251 151.339 1.00 53.71  ? 417 ASN R C   1 
ATOM   2476 O O   . ASN C 3 414 ? 222.548 197.427 151.655 1.00 53.71  ? 417 ASN R O   1 
ATOM   2477 C CB  . ASN C 3 414 ? 224.358 198.709 149.069 1.00 53.71  ? 417 ASN R CB  1 
ATOM   2478 C CG  . ASN C 3 414 ? 224.074 199.222 147.681 1.00 53.71  ? 417 ASN R CG  1 
ATOM   2479 O OD1 . ASN C 3 414 ? 222.940 199.163 147.208 1.00 53.71  ? 417 ASN R OD1 1 
ATOM   2480 N ND2 . ASN C 3 414 ? 225.104 199.727 147.014 1.00 53.71  ? 417 ASN R ND2 1 
ATOM   2481 N N   . ILE C 3 415 ? 224.503 198.459 152.076 1.00 41.82  ? 418 ILE R N   1 
ATOM   2482 C CA  . ILE C 3 415 ? 224.745 197.654 153.267 1.00 41.82  ? 418 ILE R CA  1 
ATOM   2483 C C   . ILE C 3 415 ? 223.655 197.893 154.299 1.00 41.82  ? 418 ILE R C   1 
ATOM   2484 O O   . ILE C 3 415 ? 223.002 196.954 154.765 1.00 41.82  ? 418 ILE R O   1 
ATOM   2485 C CB  . ILE C 3 415 ? 226.134 197.951 153.850 1.00 41.82  ? 418 ILE R CB  1 
ATOM   2486 C CG1 . ILE C 3 415 ? 227.209 197.391 152.949 1.00 41.82  ? 418 ILE R CG1 1 
ATOM   2487 C CG2 . ILE C 3 415 ? 226.274 197.298 155.191 1.00 41.82  ? 418 ILE R CG2 1 
ATOM   2488 C CD1 . ILE C 3 415 ? 227.083 195.928 152.732 1.00 41.82  ? 418 ILE R CD1 1 
ATOM   2489 N N   . ALA C 3 416 ? 223.407 199.155 154.633 1.00 49.25  ? 419 ALA R N   1 
ATOM   2490 C CA  . ALA C 3 416 ? 222.464 199.452 155.698 1.00 49.25  ? 419 ALA R CA  1 
ATOM   2491 C C   . ALA C 3 416 ? 221.043 199.045 155.358 1.00 49.25  ? 419 ALA R C   1 
ATOM   2492 O O   . ALA C 3 416 ? 220.208 198.978 156.262 1.00 49.25  ? 419 ALA R O   1 
ATOM   2493 C CB  . ALA C 3 416 ? 222.497 200.941 156.029 1.00 49.25  ? 419 ALA R CB  1 
ATOM   2494 N N   . ASP C 3 417 ? 220.744 198.776 154.094 1.00 56.79  ? 420 ASP R N   1 
ATOM   2495 C CA  . ASP C 3 417 ? 219.373 198.497 153.697 1.00 56.79  ? 420 ASP R CA  1 
ATOM   2496 C C   . ASP C 3 417 ? 219.143 197.045 153.304 1.00 56.79  ? 420 ASP R C   1 
ATOM   2497 O O   . ASP C 3 417 ? 217.999 196.584 153.337 1.00 56.79  ? 420 ASP R O   1 
ATOM   2498 C CB  . ASP C 3 417 ? 218.968 199.425 152.548 1.00 56.79  ? 420 ASP R CB  1 
ATOM   2499 C CG  . ASP C 3 417 ? 217.509 199.295 152.180 1.00 56.79  ? 420 ASP R CG  1 
ATOM   2500 O OD1 . ASP C 3 417 ? 216.660 199.792 152.946 1.00 56.79  ? 420 ASP R OD1 1 
ATOM   2501 O OD2 . ASP C 3 417 ? 217.208 198.721 151.118 1.00 56.79  ? 420 ASP R OD2 1 
ATOM   2502 N N   . TYR C 3 418 ? 220.195 196.306 152.948 1.00 50.88  ? 421 TYR R N   1 
ATOM   2503 C CA  . TYR C 3 418 ? 220.038 194.922 152.537 1.00 50.88  ? 421 TYR R CA  1 
ATOM   2504 C C   . TYR C 3 418 ? 220.967 193.930 153.218 1.00 50.88  ? 421 TYR R C   1 
ATOM   2505 O O   . TYR C 3 418 ? 220.697 192.729 153.141 1.00 50.88  ? 421 TYR R O   1 
ATOM   2506 C CB  . TYR C 3 418 ? 220.226 194.791 151.022 1.00 50.88  ? 421 TYR R CB  1 
ATOM   2507 C CG  . TYR C 3 418 ? 219.183 195.517 150.219 1.00 50.88  ? 421 TYR R CG  1 
ATOM   2508 C CD1 . TYR C 3 418 ? 217.851 195.460 150.578 1.00 50.88  ? 421 TYR R CD1 1 
ATOM   2509 C CD2 . TYR C 3 418 ? 219.528 196.255 149.100 1.00 50.88  ? 421 TYR R CD2 1 
ATOM   2510 C CE1 . TYR C 3 418 ? 216.890 196.114 149.850 1.00 50.88  ? 421 TYR R CE1 1 
ATOM   2511 C CE2 . TYR C 3 418 ? 218.572 196.919 148.365 1.00 50.88  ? 421 TYR R CE2 1 
ATOM   2512 C CZ  . TYR C 3 418 ? 217.254 196.846 148.748 1.00 50.88  ? 421 TYR R CZ  1 
ATOM   2513 O OH  . TYR C 3 418 ? 216.290 197.503 148.023 1.00 50.88  ? 421 TYR R OH  1 
ATOM   2514 N N   . ASN C 3 419 ? 222.043 194.364 153.864 1.00 39.97  ? 422 ASN R N   1 
ATOM   2515 C CA  . ASN C 3 419 ? 222.988 193.419 154.444 1.00 39.97  ? 422 ASN R CA  1 
ATOM   2516 C C   . ASN C 3 419 ? 223.118 193.548 155.952 1.00 39.97  ? 422 ASN R C   1 
ATOM   2517 O O   . ASN C 3 419 ? 222.961 192.556 156.667 1.00 39.97  ? 422 ASN R O   1 
ATOM   2518 C CB  . ASN C 3 419 ? 224.360 193.595 153.787 1.00 39.97  ? 422 ASN R CB  1 
ATOM   2519 C CG  . ASN C 3 419 ? 224.310 193.423 152.293 1.00 39.97  ? 422 ASN R CG  1 
ATOM   2520 O OD1 . ASN C 3 419 ? 224.446 192.318 151.779 1.00 39.97  ? 422 ASN R OD1 1 
ATOM   2521 N ND2 . ASN C 3 419 ? 224.110 194.519 151.582 1.00 39.97  ? 422 ASN R ND2 1 
ATOM   2522 N N   . TYR C 3 420 ? 223.408 194.738 156.462 1.00 34.11  ? 423 TYR R N   1 
ATOM   2523 C CA  . TYR C 3 420 ? 223.612 194.932 157.893 1.00 34.11  ? 423 TYR R CA  1 
ATOM   2524 C C   . TYR C 3 420 ? 223.009 196.269 158.281 1.00 34.11  ? 423 TYR R C   1 
ATOM   2525 O O   . TYR C 3 420 ? 223.549 197.319 157.924 1.00 34.11  ? 423 TYR R O   1 
ATOM   2526 C CB  . TYR C 3 420 ? 225.092 194.888 158.248 1.00 34.11  ? 423 TYR R CB  1 
ATOM   2527 C CG  . TYR C 3 420 ? 225.351 194.808 159.726 1.00 34.11  ? 423 TYR R CG  1 
ATOM   2528 C CD1 . TYR C 3 420 ? 224.667 193.914 160.517 1.00 34.11  ? 423 TYR R CD1 1 
ATOM   2529 C CD2 . TYR C 3 420 ? 226.286 195.621 160.328 1.00 34.11  ? 423 TYR R CD2 1 
ATOM   2530 C CE1 . TYR C 3 420 ? 224.903 193.834 161.860 1.00 34.11  ? 423 TYR R CE1 1 
ATOM   2531 C CE2 . TYR C 3 420 ? 226.526 195.547 161.673 1.00 34.11  ? 423 TYR R CE2 1 
ATOM   2532 C CZ  . TYR C 3 420 ? 225.830 194.653 162.434 1.00 34.11  ? 423 TYR R CZ  1 
ATOM   2533 O OH  . TYR C 3 420 ? 226.066 194.573 163.781 1.00 34.11  ? 423 TYR R OH  1 
ATOM   2534 N N   . LYS C 3 421 ? 221.901 196.236 159.011 1.00 44.19  ? 424 LYS R N   1 
ATOM   2535 C CA  . LYS C 3 421 ? 221.200 197.441 159.421 1.00 44.19  ? 424 LYS R CA  1 
ATOM   2536 C C   . LYS C 3 421 ? 221.268 197.562 160.933 1.00 44.19  ? 424 LYS R C   1 
ATOM   2537 O O   . LYS C 3 421 ? 221.028 196.586 161.646 1.00 44.19  ? 424 LYS R O   1 
ATOM   2538 C CB  . LYS C 3 421 ? 219.748 197.417 158.951 1.00 44.19  ? 424 LYS R CB  1 
ATOM   2539 C CG  . LYS C 3 421 ? 218.914 198.583 159.436 1.00 44.19  ? 424 LYS R CG  1 
ATOM   2540 C CD  . LYS C 3 421 ? 219.581 199.911 159.152 1.00 44.19  ? 424 LYS R CD  1 
ATOM   2541 C CE  . LYS C 3 421 ? 218.569 201.030 159.144 1.00 44.19  ? 424 LYS R CE  1 
ATOM   2542 N NZ  . LYS C 3 421 ? 217.384 200.665 158.329 1.00 44.19  ? 424 LYS R NZ  1 
ATOM   2543 N N   . LEU C 3 422 ? 221.594 198.740 161.407 1.00 49.14  ? 425 LEU R N   1 
ATOM   2544 C CA  . LEU C 3 422 ? 221.701 199.121 162.802 1.00 49.14  ? 425 LEU R CA  1 
ATOM   2545 C C   . LEU C 3 422 ? 220.438 199.831 163.267 1.00 49.14  ? 425 LEU R C   1 
ATOM   2546 O O   . LEU C 3 422 ? 219.754 200.482 162.473 1.00 49.14  ? 425 LEU R O   1 
ATOM   2547 C CB  . LEU C 3 422 ? 222.889 200.053 163.010 1.00 49.14  ? 425 LEU R CB  1 
ATOM   2548 C CG  . LEU C 3 422 ? 224.247 199.431 162.774 1.00 49.14  ? 425 LEU R CG  1 
ATOM   2549 C CD1 . LEU C 3 422 ? 225.297 200.507 162.840 1.00 49.14  ? 425 LEU R CD1 1 
ATOM   2550 C CD2 . LEU C 3 422 ? 224.489 198.377 163.819 1.00 49.14  ? 425 LEU R CD2 1 
ATOM   2551 N N   . PRO C 3 423 ? 220.111 199.743 164.549 1.00 58.27  ? 426 PRO R N   1 
ATOM   2552 C CA  . PRO C 3 423 ? 218.958 200.486 165.065 1.00 58.27  ? 426 PRO R CA  1 
ATOM   2553 C C   . PRO C 3 423 ? 219.215 201.982 165.108 1.00 58.27  ? 426 PRO R C   1 
ATOM   2554 O O   . PRO C 3 423 ? 220.240 202.455 164.614 1.00 58.27  ? 426 PRO R O   1 
ATOM   2555 C CB  . PRO C 3 423 ? 218.773 199.906 166.470 1.00 58.27  ? 426 PRO R CB  1 
ATOM   2556 C CG  . PRO C 3 423 ? 220.116 199.420 166.847 1.00 58.27  ? 426 PRO R CG  1 
ATOM   2557 C CD  . PRO C 3 423 ? 220.742 198.915 165.587 1.00 58.27  ? 426 PRO R CD  1 
ATOM   2558 N N   . ASP C 3 424 ? 218.285 202.744 165.673 1.00 70.15  ? 427 ASP R N   1 
ATOM   2559 C CA  . ASP C 3 424 ? 218.493 204.176 165.833 1.00 70.15  ? 427 ASP R CA  1 
ATOM   2560 C C   . ASP C 3 424 ? 219.089 204.533 167.185 1.00 70.15  ? 427 ASP R C   1 
ATOM   2561 O O   . ASP C 3 424 ? 219.755 205.566 167.305 1.00 70.15  ? 427 ASP R O   1 
ATOM   2562 C CB  . ASP C 3 424 ? 217.172 204.924 165.643 1.00 70.15  ? 427 ASP R CB  1 
ATOM   2563 C CG  . ASP C 3 424 ? 216.840 205.156 164.184 1.00 70.15  ? 427 ASP R CG  1 
ATOM   2564 O OD1 . ASP C 3 424 ? 217.461 204.498 163.322 1.00 70.15  ? 427 ASP R OD1 1 
ATOM   2565 O OD2 . ASP C 3 424 ? 215.961 205.995 163.896 1.00 70.15  ? 427 ASP R OD2 1 
ATOM   2566 N N   . ASP C 3 425 ? 218.868 203.703 168.200 1.00 72.54  ? 428 ASP R N   1 
ATOM   2567 C CA  . ASP C 3 425 ? 219.364 203.931 169.556 1.00 72.54  ? 428 ASP R CA  1 
ATOM   2568 C C   . ASP C 3 425 ? 220.610 203.107 169.849 1.00 72.54  ? 428 ASP R C   1 
ATOM   2569 O O   . ASP C 3 425 ? 220.773 202.576 170.950 1.00 72.54  ? 428 ASP R O   1 
ATOM   2570 C CB  . ASP C 3 425 ? 218.268 203.639 170.575 1.00 72.54  ? 428 ASP R CB  1 
ATOM   2571 C CG  . ASP C 3 425 ? 217.803 202.197 170.540 1.00 72.54  ? 428 ASP R CG  1 
ATOM   2572 O OD1 . ASP C 3 425 ? 218.294 201.424 169.695 1.00 72.54  ? 428 ASP R OD1 1 
ATOM   2573 O OD2 . ASP C 3 425 ? 216.938 201.835 171.362 1.00 72.54  ? 428 ASP R OD2 1 
ATOM   2574 N N   . PHE C 3 426 ? 221.493 202.981 168.864 1.00 54.67  ? 429 PHE R N   1 
ATOM   2575 C CA  . PHE C 3 426 ? 222.621 202.067 168.953 1.00 54.67  ? 429 PHE R CA  1 
ATOM   2576 C C   . PHE C 3 426 ? 223.552 202.431 170.104 1.00 54.67  ? 429 PHE R C   1 
ATOM   2577 O O   . PHE C 3 426 ? 223.737 203.602 170.440 1.00 54.67  ? 429 PHE R O   1 
ATOM   2578 C CB  . PHE C 3 426 ? 223.389 202.082 167.637 1.00 54.67  ? 429 PHE R CB  1 
ATOM   2579 C CG  . PHE C 3 426 ? 224.472 201.064 167.559 1.00 54.67  ? 429 PHE R CG  1 
ATOM   2580 C CD1 . PHE C 3 426 ? 224.231 199.753 167.907 1.00 54.67  ? 429 PHE R CD1 1 
ATOM   2581 C CD2 . PHE C 3 426 ? 225.727 201.411 167.114 1.00 54.67  ? 429 PHE R CD2 1 
ATOM   2582 C CE1 . PHE C 3 426 ? 225.227 198.816 167.828 1.00 54.67  ? 429 PHE R CE1 1 
ATOM   2583 C CE2 . PHE C 3 426 ? 226.721 200.478 167.034 1.00 54.67  ? 429 PHE R CE2 1 
ATOM   2584 C CZ  . PHE C 3 426 ? 226.472 199.180 167.392 1.00 54.67  ? 429 PHE R CZ  1 
ATOM   2585 N N   . THR C 3 427 ? 224.125 201.400 170.722 1.00 60.38  ? 430 THR R N   1 
ATOM   2586 C CA  . THR C 3 427 ? 225.194 201.536 171.701 1.00 60.38  ? 430 THR R CA  1 
ATOM   2587 C C   . THR C 3 427 ? 226.305 200.565 171.333 1.00 60.38  ? 430 THR R C   1 
ATOM   2588 O O   . THR C 3 427 ? 226.072 199.558 170.662 1.00 60.38  ? 430 THR R O   1 
ATOM   2589 C CB  . THR C 3 427 ? 224.714 201.251 173.122 1.00 60.38  ? 430 THR R CB  1 
ATOM   2590 O OG1 . THR C 3 427 ? 224.430 199.854 173.251 1.00 60.38  ? 430 THR R OG1 1 
ATOM   2591 C CG2 . THR C 3 427 ? 223.463 202.050 173.433 1.00 60.38  ? 430 THR R CG2 1 
ATOM   2592 N N   . GLY C 3 428 ? 227.519 200.864 171.779 1.00 52.80  ? 431 GLY R N   1 
ATOM   2593 C CA  . GLY C 3 428 ? 228.687 200.143 171.318 1.00 52.80  ? 431 GLY R CA  1 
ATOM   2594 C C   . GLY C 3 428 ? 229.179 200.698 169.999 1.00 52.80  ? 431 GLY R C   1 
ATOM   2595 O O   . GLY C 3 428 ? 228.537 201.535 169.366 1.00 52.80  ? 431 GLY R O   1 
ATOM   2596 N N   . CYS C 3 429 ? 230.350 200.232 169.567 1.00 42.16  ? 432 CYS R N   1 
ATOM   2597 C CA  . CYS C 3 429 ? 231.005 200.958 168.493 1.00 42.16  ? 432 CYS R CA  1 
ATOM   2598 C C   . CYS C 3 429 ? 231.982 200.135 167.678 1.00 42.16  ? 432 CYS R C   1 
ATOM   2599 O O   . CYS C 3 429 ? 232.343 199.011 168.026 1.00 42.16  ? 432 CYS R O   1 
ATOM   2600 C CB  . CYS C 3 429 ? 231.603 202.223 169.056 1.00 42.16  ? 432 CYS R CB  1 
ATOM   2601 S SG  . CYS C 3 429 ? 232.905 202.355 170.304 1.00 42.16  ? 432 CYS R SG  1 
ATOM   2602 N N   . VAL C 3 430 ? 232.433 200.765 166.593 1.00 28.01  ? 433 VAL R N   1 
ATOM   2603 C CA  . VAL C 3 430 ? 232.732 200.123 165.322 1.00 28.01  ? 433 VAL R CA  1 
ATOM   2604 C C   . VAL C 3 430 ? 234.148 200.497 164.903 1.00 28.01  ? 433 VAL R C   1 
ATOM   2605 O O   . VAL C 3 430 ? 234.442 201.677 164.692 1.00 28.01  ? 433 VAL R O   1 
ATOM   2606 C CB  . VAL C 3 430 ? 231.724 200.539 164.239 1.00 28.01  ? 433 VAL R CB  1 
ATOM   2607 C CG1 . VAL C 3 430 ? 230.358 200.069 164.610 1.00 28.01  ? 433 VAL R CG1 1 
ATOM   2608 C CG2 . VAL C 3 430 ? 231.655 202.030 164.097 1.00 28.01  ? 433 VAL R CG2 1 
ATOM   2609 N N   . ILE C 3 431 ? 235.031 199.514 164.796 1.00 24.78  ? 434 ILE R N   1 
ATOM   2610 C CA  . ILE C 3 431 ? 236.367 199.800 164.321 1.00 24.78  ? 434 ILE R CA  1 
ATOM   2611 C C   . ILE C 3 431 ? 236.487 199.235 162.919 1.00 24.78  ? 434 ILE R C   1 
ATOM   2612 O O   . ILE C 3 431 ? 235.753 198.331 162.528 1.00 24.78  ? 434 ILE R O   1 
ATOM   2613 C CB  . ILE C 3 431 ? 237.470 199.245 165.231 1.00 24.78  ? 434 ILE R CB  1 
ATOM   2614 C CG1 . ILE C 3 431 ? 237.495 197.741 165.237 1.00 24.78  ? 434 ILE R CG1 1 
ATOM   2615 C CG2 . ILE C 3 431 ? 237.131 199.540 166.649 1.00 24.78  ? 434 ILE R CG2 1 
ATOM   2616 C CD1 . ILE C 3 431 ? 238.738 197.249 165.934 1.00 24.78  ? 434 ILE R CD1 1 
ATOM   2617 N N   . ALA C 3 432 ? 237.417 199.776 162.141 1.00 19.76  ? 435 ALA R N   1 
ATOM   2618 C CA  . ALA C 3 432 ? 237.529 199.388 160.740 1.00 19.76  ? 435 ALA R CA  1 
ATOM   2619 C C   . ALA C 3 432 ? 238.931 199.706 160.258 1.00 19.76  ? 435 ALA R C   1 
ATOM   2620 O O   . ALA C 3 432 ? 239.221 200.864 159.958 1.00 19.76  ? 435 ALA R O   1 
ATOM   2621 C CB  . ALA C 3 432 ? 236.495 200.118 159.903 1.00 19.76  ? 435 ALA R CB  1 
ATOM   2622 N N   . TRP C 3 433 ? 239.784 198.701 160.152 1.00 24.00  ? 436 TRP R N   1 
ATOM   2623 C CA  . TRP C 3 433 ? 241.157 198.927 159.741 1.00 24.00  ? 436 TRP R CA  1 
ATOM   2624 C C   . TRP C 3 433 ? 241.395 198.365 158.352 1.00 24.00  ? 436 TRP R C   1 
ATOM   2625 O O   . TRP C 3 433 ? 240.877 197.303 158.013 1.00 24.00  ? 436 TRP R O   1 
ATOM   2626 C CB  . TRP C 3 433 ? 242.137 198.308 160.729 1.00 24.00  ? 436 TRP R CB  1 
ATOM   2627 C CG  . TRP C 3 433 ? 242.100 196.828 160.848 1.00 24.00  ? 436 TRP R CG  1 
ATOM   2628 C CD1 . TRP C 3 433 ? 242.965 195.947 160.283 1.00 24.00  ? 436 TRP R CD1 1 
ATOM   2629 C CD2 . TRP C 3 433 ? 241.189 196.051 161.626 1.00 24.00  ? 436 TRP R CD2 1 
ATOM   2630 N NE1 . TRP C 3 433 ? 242.639 194.666 160.644 1.00 24.00  ? 436 TRP R NE1 1 
ATOM   2631 C CE2 . TRP C 3 433 ? 241.549 194.707 161.469 1.00 24.00  ? 436 TRP R CE2 1 
ATOM   2632 C CE3 . TRP C 3 433 ? 240.097 196.361 162.431 1.00 24.00  ? 436 TRP R CE3 1 
ATOM   2633 C CZ2 . TRP C 3 433 ? 240.860 193.682 162.083 1.00 24.00  ? 436 TRP R CZ2 1 
ATOM   2634 C CZ3 . TRP C 3 433 ? 239.416 195.338 163.039 1.00 24.00  ? 436 TRP R CZ3 1 
ATOM   2635 C CH2 . TRP C 3 433 ? 239.797 194.019 162.863 1.00 24.00  ? 436 TRP R CH2 1 
ATOM   2636 N N   . ASN C 3 434 ? 242.174 199.084 157.550 1.00 32.37  ? 437 ASN R N   1 
ATOM   2637 C CA  . ASN C 3 434 ? 242.502 198.603 156.216 1.00 32.37  ? 437 ASN R CA  1 
ATOM   2638 C C   . ASN C 3 434 ? 243.185 197.250 156.320 1.00 32.37  ? 437 ASN R C   1 
ATOM   2639 O O   . ASN C 3 434 ? 243.903 196.973 157.282 1.00 32.37  ? 437 ASN R O   1 
ATOM   2640 C CB  . ASN C 3 434 ? 243.410 199.600 155.489 1.00 32.37  ? 437 ASN R CB  1 
ATOM   2641 C CG  . ASN C 3 434 ? 243.707 199.194 154.051 1.00 32.37  ? 437 ASN R CG  1 
ATOM   2642 O OD1 . ASN C 3 434 ? 244.160 198.085 153.785 1.00 32.37  ? 437 ASN R OD1 1 
ATOM   2643 N ND2 . ASN C 3 434 ? 243.470 200.106 153.121 1.00 32.37  ? 437 ASN R ND2 1 
ATOM   2644 N N   . SER C 3 435 ? 242.941 196.396 155.330 1.00 35.02  ? 438 SER R N   1 
ATOM   2645 C CA  . SER C 3 435 ? 243.497 195.051 155.370 1.00 35.02  ? 438 SER R CA  1 
ATOM   2646 C C   . SER C 3 435 ? 244.008 194.595 154.012 1.00 35.02  ? 438 SER R C   1 
ATOM   2647 O O   . SER C 3 435 ? 244.155 193.388 153.795 1.00 35.02  ? 438 SER R O   1 
ATOM   2648 C CB  . SER C 3 435 ? 242.457 194.068 155.871 1.00 35.02  ? 438 SER R CB  1 
ATOM   2649 O OG  . SER C 3 435 ? 241.221 194.317 155.237 1.00 35.02  ? 438 SER R OG  1 
ATOM   2650 N N   . ASN C 3 436 ? 244.301 195.525 153.103 1.00 44.79  ? 439 ASN R N   1 
ATOM   2651 C CA  . ASN C 3 436 ? 244.605 195.156 151.727 1.00 44.79  ? 439 ASN R CA  1 
ATOM   2652 C C   . ASN C 3 436 ? 245.806 194.235 151.619 1.00 44.79  ? 439 ASN R C   1 
ATOM   2653 O O   . ASN C 3 436 ? 245.943 193.529 150.617 1.00 44.79  ? 439 ASN R O   1 
ATOM   2654 C CB  . ASN C 3 436 ? 244.843 196.403 150.889 1.00 44.79  ? 439 ASN R CB  1 
ATOM   2655 C CG  . ASN C 3 436 ? 244.936 196.094 149.423 1.00 44.79  ? 439 ASN R CG  1 
ATOM   2656 O OD1 . ASN C 3 436 ? 244.162 195.295 148.903 1.00 44.79  ? 439 ASN R OD1 1 
ATOM   2657 N ND2 . ASN C 3 436 ? 245.886 196.718 148.742 1.00 44.79  ? 439 ASN R ND2 1 
ATOM   2658 N N   . ASN C 3 437 ? 246.681 194.228 152.619 1.00 43.86  ? 440 ASN R N   1 
ATOM   2659 C CA  . ASN C 3 437 ? 247.797 193.295 152.606 1.00 43.86  ? 440 ASN R CA  1 
ATOM   2660 C C   . ASN C 3 437 ? 247.353 191.869 152.898 1.00 43.86  ? 440 ASN R C   1 
ATOM   2661 O O   . ASN C 3 437 ? 248.044 190.922 152.509 1.00 43.86  ? 440 ASN R O   1 
ATOM   2662 C CB  . ASN C 3 437 ? 248.856 193.736 153.614 1.00 43.86  ? 440 ASN R CB  1 
ATOM   2663 C CG  . ASN C 3 437 ? 248.258 194.117 154.948 1.00 43.86  ? 440 ASN R CG  1 
ATOM   2664 O OD1 . ASN C 3 437 ? 247.052 194.006 155.148 1.00 43.86  ? 440 ASN R OD1 1 
ATOM   2665 N ND2 . ASN C 3 437 ? 249.097 194.575 155.867 1.00 43.86  ? 440 ASN R ND2 1 
ATOM   2666 N N   . LEU C 3 438 ? 246.215 191.691 153.571 1.00 37.11  ? 441 LEU R N   1 
ATOM   2667 C CA  . LEU C 3 438 ? 245.770 190.360 153.967 1.00 37.11  ? 441 LEU R CA  1 
ATOM   2668 C C   . LEU C 3 438 ? 244.704 189.785 153.045 1.00 37.11  ? 441 LEU R C   1 
ATOM   2669 O O   . LEU C 3 438 ? 244.780 188.612 152.673 1.00 37.11  ? 441 LEU R O   1 
ATOM   2670 C CB  . LEU C 3 438 ? 245.235 190.383 155.399 1.00 37.11  ? 441 LEU R CB  1 
ATOM   2671 C CG  . LEU C 3 438 ? 246.191 189.984 156.522 1.00 37.11  ? 441 LEU R CG  1 
ATOM   2672 C CD1 . LEU C 3 438 ? 247.205 191.077 156.777 1.00 37.11  ? 441 LEU R CD1 1 
ATOM   2673 C CD2 . LEU C 3 438 ? 245.419 189.663 157.785 1.00 37.11  ? 441 LEU R CD2 1 
ATOM   2674 N N   . ASP C 3 439 ? 243.706 190.581 152.668 1.00 40.43  ? 442 ASP R N   1 
ATOM   2675 C CA  . ASP C 3 439 ? 242.551 190.034 151.968 1.00 40.43  ? 442 ASP R CA  1 
ATOM   2676 C C   . ASP C 3 439 ? 242.815 189.860 150.479 1.00 40.43  ? 442 ASP R C   1 
ATOM   2677 O O   . ASP C 3 439 ? 242.784 188.742 149.960 1.00 40.43  ? 442 ASP R O   1 
ATOM   2678 C CB  . ASP C 3 439 ? 241.340 190.933 152.188 1.00 40.43  ? 442 ASP R CB  1 
ATOM   2679 C CG  . ASP C 3 439 ? 240.639 190.640 153.483 1.00 40.43  ? 442 ASP R CG  1 
ATOM   2680 O OD1 . ASP C 3 439 ? 241.028 189.668 154.161 1.00 40.43  ? 442 ASP R OD1 1 
ATOM   2681 O OD2 . ASP C 3 439 ? 239.698 191.381 153.826 1.00 40.43  ? 442 ASP R OD2 1 
ATOM   2682 N N   . SER C 3 440 ? 243.066 190.956 149.775 1.00 47.63  ? 443 SER R N   1 
ATOM   2683 C CA  . SER C 3 440 ? 243.174 190.904 148.327 1.00 47.63  ? 443 SER R CA  1 
ATOM   2684 C C   . SER C 3 440 ? 244.396 190.108 147.897 1.00 47.63  ? 443 SER R C   1 
ATOM   2685 O O   . SER C 3 440 ? 245.427 190.093 148.570 1.00 47.63  ? 443 SER R O   1 
ATOM   2686 C CB  . SER C 3 440 ? 243.259 192.310 147.750 1.00 47.63  ? 443 SER R CB  1 
ATOM   2687 O OG  . SER C 3 440 ? 244.543 192.859 147.975 1.00 47.63  ? 443 SER R OG  1 
ATOM   2688 N N   . LYS C 3 441 ? 244.269 189.440 146.756 1.00 50.93  ? 444 LYS R N   1 
ATOM   2689 C CA  . LYS C 3 441 ? 245.377 188.715 146.158 1.00 50.93  ? 444 LYS R CA  1 
ATOM   2690 C C   . LYS C 3 441 ? 245.378 188.984 144.663 1.00 50.93  ? 444 LYS R C   1 
ATOM   2691 O O   . LYS C 3 441 ? 244.350 189.329 144.077 1.00 50.93  ? 444 LYS R O   1 
ATOM   2692 C CB  . LYS C 3 441 ? 245.289 187.211 146.435 1.00 50.93  ? 444 LYS R CB  1 
ATOM   2693 C CG  . LYS C 3 441 ? 244.055 186.551 145.856 1.00 50.93  ? 444 LYS R CG  1 
ATOM   2694 C CD  . LYS C 3 441 ? 244.160 185.037 145.897 1.00 50.93  ? 444 LYS R CD  1 
ATOM   2695 C CE  . LYS C 3 441 ? 244.223 184.526 147.325 1.00 50.93  ? 444 LYS R CE  1 
ATOM   2696 N NZ  . LYS C 3 441 ? 243.319 185.278 148.237 1.00 50.93  ? 444 LYS R NZ  1 
ATOM   2697 N N   . VAL C 3 442 ? 246.553 188.826 144.049 1.00 55.68  ? 445 VAL R N   1 
ATOM   2698 C CA  . VAL C 3 442 ? 246.697 189.132 142.632 1.00 55.68  ? 445 VAL R CA  1 
ATOM   2699 C C   . VAL C 3 442 ? 245.775 188.238 141.817 1.00 55.68  ? 445 VAL R C   1 
ATOM   2700 O O   . VAL C 3 442 ? 245.706 187.020 142.027 1.00 55.68  ? 445 VAL R O   1 
ATOM   2701 C CB  . VAL C 3 442 ? 248.165 188.994 142.202 1.00 55.68  ? 445 VAL R CB  1 
ATOM   2702 C CG1 . VAL C 3 442 ? 248.673 187.585 142.450 1.00 55.68  ? 445 VAL R CG1 1 
ATOM   2703 C CG2 . VAL C 3 442 ? 248.322 189.369 140.739 1.00 55.68  ? 445 VAL R CG2 1 
ATOM   2704 N N   . GLY C 3 443 ? 245.041 188.849 140.890 1.00 55.04  ? 446 GLY R N   1 
ATOM   2705 C CA  . GLY C 3 443 ? 244.036 188.171 140.109 1.00 55.04  ? 446 GLY R CA  1 
ATOM   2706 C C   . GLY C 3 443 ? 242.636 188.255 140.681 1.00 55.04  ? 446 GLY R C   1 
ATOM   2707 O O   . GLY C 3 443 ? 241.668 188.039 139.943 1.00 55.04  ? 446 GLY R O   1 
ATOM   2708 N N   . GLY C 3 444 ? 242.502 188.570 141.967 1.00 50.36  ? 447 GLY R N   1 
ATOM   2709 C CA  . GLY C 3 444 ? 241.194 188.710 142.573 1.00 50.36  ? 447 GLY R CA  1 
ATOM   2710 C C   . GLY C 3 444 ? 240.962 187.816 143.772 1.00 50.36  ? 447 GLY R C   1 
ATOM   2711 O O   . GLY C 3 444 ? 241.562 186.746 143.885 1.00 50.36  ? 447 GLY R O   1 
ATOM   2712 N N   . ASN C 3 445 ? 240.094 188.253 144.680 1.00 43.19  ? 448 ASN R N   1 
ATOM   2713 C CA  . ASN C 3 445 ? 239.663 187.456 145.826 1.00 43.19  ? 448 ASN R CA  1 
ATOM   2714 C C   . ASN C 3 445 ? 238.143 187.480 145.829 1.00 43.19  ? 448 ASN R C   1 
ATOM   2715 O O   . ASN C 3 445 ? 237.537 188.408 146.368 1.00 43.19  ? 448 ASN R O   1 
ATOM   2716 C CB  . ASN C 3 445 ? 240.216 188.003 147.131 1.00 43.19  ? 448 ASN R CB  1 
ATOM   2717 C CG  . ASN C 3 445 ? 239.800 187.180 148.321 1.00 43.19  ? 448 ASN R CG  1 
ATOM   2718 O OD1 . ASN C 3 445 ? 239.182 186.131 148.174 1.00 43.19  ? 448 ASN R OD1 1 
ATOM   2719 N ND2 . ASN C 3 445 ? 240.128 187.654 149.512 1.00 43.19  ? 448 ASN R ND2 1 
ATOM   2720 N N   . TYR C 3 446 ? 237.527 186.464 145.245 1.00 40.84  ? 449 TYR R N   1 
ATOM   2721 C CA  . TYR C 3 446 ? 236.092 186.472 145.019 1.00 40.84  ? 449 TYR R CA  1 
ATOM   2722 C C   . TYR C 3 446 ? 235.287 185.988 146.214 1.00 40.84  ? 449 TYR R C   1 
ATOM   2723 O O   . TYR C 3 446 ? 234.057 185.986 146.143 1.00 40.84  ? 449 TYR R O   1 
ATOM   2724 C CB  . TYR C 3 446 ? 235.755 185.612 143.805 1.00 40.84  ? 449 TYR R CB  1 
ATOM   2725 C CG  . TYR C 3 446 ? 236.142 186.227 142.487 1.00 40.84  ? 449 TYR R CG  1 
ATOM   2726 C CD1 . TYR C 3 446 ? 235.438 187.300 141.970 1.00 40.84  ? 449 TYR R CD1 1 
ATOM   2727 C CD2 . TYR C 3 446 ? 237.211 185.736 141.762 1.00 40.84  ? 449 TYR R CD2 1 
ATOM   2728 C CE1 . TYR C 3 446 ? 235.784 187.860 140.768 1.00 40.84  ? 449 TYR R CE1 1 
ATOM   2729 C CE2 . TYR C 3 446 ? 237.567 186.293 140.563 1.00 40.84  ? 449 TYR R CE2 1 
ATOM   2730 C CZ  . TYR C 3 446 ? 236.850 187.354 140.070 1.00 40.84  ? 449 TYR R CZ  1 
ATOM   2731 O OH  . TYR C 3 446 ? 237.202 187.915 138.869 1.00 40.84  ? 449 TYR R OH  1 
ATOM   2732 N N   . ASN C 3 447 ? 235.935 185.594 147.308 1.00 33.34  ? 450 ASN R N   1 
ATOM   2733 C CA  . ASN C 3 447 ? 235.219 184.914 148.380 1.00 33.34  ? 450 ASN R CA  1 
ATOM   2734 C C   . ASN C 3 447 ? 234.352 185.837 149.219 1.00 33.34  ? 450 ASN R C   1 
ATOM   2735 O O   . ASN C 3 447 ? 233.673 185.347 150.124 1.00 33.34  ? 450 ASN R O   1 
ATOM   2736 C CB  . ASN C 3 447 ? 236.197 184.200 149.294 1.00 33.34  ? 450 ASN R CB  1 
ATOM   2737 C CG  . ASN C 3 447 ? 237.186 183.386 148.533 1.00 33.34  ? 450 ASN R CG  1 
ATOM   2738 O OD1 . ASN C 3 447 ? 236.931 182.992 147.401 1.00 33.34  ? 450 ASN R OD1 1 
ATOM   2739 N ND2 . ASN C 3 447 ? 238.330 183.122 149.142 1.00 33.34  ? 450 ASN R ND2 1 
ATOM   2740 N N   . TYR C 3 448 ? 234.369 187.141 148.977 1.00 29.94  ? 451 TYR R N   1 
ATOM   2741 C CA  . TYR C 3 448 ? 233.561 188.082 149.736 1.00 29.94  ? 451 TYR R CA  1 
ATOM   2742 C C   . TYR C 3 448 ? 232.409 188.570 148.874 1.00 29.94  ? 451 TYR R C   1 
ATOM   2743 O O   . TYR C 3 448 ? 232.633 189.162 147.816 1.00 29.94  ? 451 TYR R O   1 
ATOM   2744 C CB  . TYR C 3 448 ? 234.405 189.256 150.213 1.00 29.94  ? 451 TYR R CB  1 
ATOM   2745 C CG  . TYR C 3 448 ? 235.465 188.860 151.202 1.00 29.94  ? 451 TYR R CG  1 
ATOM   2746 C CD1 . TYR C 3 448 ? 235.140 188.570 152.509 1.00 29.94  ? 451 TYR R CD1 1 
ATOM   2747 C CD2 . TYR C 3 448 ? 236.788 188.782 150.831 1.00 29.94  ? 451 TYR R CD2 1 
ATOM   2748 C CE1 . TYR C 3 448 ? 236.100 188.213 153.415 1.00 29.94  ? 451 TYR R CE1 1 
ATOM   2749 C CE2 . TYR C 3 448 ? 237.752 188.424 151.732 1.00 29.94  ? 451 TYR R CE2 1 
ATOM   2750 C CZ  . TYR C 3 448 ? 237.401 188.140 153.021 1.00 29.94  ? 451 TYR R CZ  1 
ATOM   2751 O OH  . TYR C 3 448 ? 238.362 187.780 153.926 1.00 29.94  ? 451 TYR R OH  1 
ATOM   2752 N N   . LEU C 3 449 ? 231.185 188.337 149.332 1.00 29.33  ? 452 LEU R N   1 
ATOM   2753 C CA  . LEU C 3 449 ? 229.990 188.597 148.547 1.00 29.33  ? 452 LEU R CA  1 
ATOM   2754 C C   . LEU C 3 449 ? 229.044 189.495 149.330 1.00 29.33  ? 452 LEU R C   1 
ATOM   2755 O O   . LEU C 3 449 ? 229.118 189.583 150.555 1.00 29.33  ? 452 LEU R O   1 
ATOM   2756 C CB  . LEU C 3 449 ? 229.288 187.294 148.188 1.00 29.33  ? 452 LEU R CB  1 
ATOM   2757 C CG  . LEU C 3 449 ? 230.223 186.211 147.674 1.00 29.33  ? 452 LEU R CG  1 
ATOM   2758 C CD1 . LEU C 3 449 ? 229.455 184.953 147.361 1.00 29.33  ? 452 LEU R CD1 1 
ATOM   2759 C CD2 . LEU C 3 449 ? 230.943 186.707 146.452 1.00 29.33  ? 452 LEU R CD2 1 
ATOM   2760 N N   . TYR C 3 450 ? 228.143 190.161 148.614 1.00 35.31  ? 453 TYR R N   1 
ATOM   2761 C CA  . TYR C 3 450 ? 227.206 191.074 149.251 1.00 35.31  ? 453 TYR R CA  1 
ATOM   2762 C C   . TYR C 3 450 ? 225.893 191.038 148.495 1.00 35.31  ? 453 TYR R C   1 
ATOM   2763 O O   . TYR C 3 450 ? 225.889 190.967 147.266 1.00 35.31  ? 453 TYR R O   1 
ATOM   2764 C CB  . TYR C 3 450 ? 227.756 192.492 149.261 1.00 35.31  ? 453 TYR R CB  1 
ATOM   2765 C CG  . TYR C 3 450 ? 227.801 193.141 147.903 1.00 35.31  ? 453 TYR R CG  1 
ATOM   2766 C CD1 . TYR C 3 450 ? 228.828 192.876 147.023 1.00 35.31  ? 453 TYR R CD1 1 
ATOM   2767 C CD2 . TYR C 3 450 ? 226.856 194.076 147.532 1.00 35.31  ? 453 TYR R CD2 1 
ATOM   2768 C CE1 . TYR C 3 450 ? 228.893 193.486 145.793 1.00 35.31  ? 453 TYR R CE1 1 
ATOM   2769 C CE2 . TYR C 3 450 ? 226.913 194.693 146.304 1.00 35.31  ? 453 TYR R CE2 1 
ATOM   2770 C CZ  . TYR C 3 450 ? 227.935 194.393 145.440 1.00 35.31  ? 453 TYR R CZ  1 
ATOM   2771 O OH  . TYR C 3 450 ? 227.999 195.003 144.214 1.00 35.31  ? 453 TYR R OH  1 
ATOM   2772 N N   . ARG C 3 451 ? 224.785 191.096 149.223 1.00 38.88  ? 454 ARG R N   1 
ATOM   2773 C CA  . ARG C 3 451 ? 223.483 191.070 148.574 1.00 38.88  ? 454 ARG R CA  1 
ATOM   2774 C C   . ARG C 3 451 ? 223.274 192.338 147.764 1.00 38.88  ? 454 ARG R C   1 
ATOM   2775 O O   . ARG C 3 451 ? 223.875 193.377 148.033 1.00 38.88  ? 454 ARG R O   1 
ATOM   2776 C CB  . ARG C 3 451 ? 222.372 190.923 149.604 1.00 38.88  ? 454 ARG R CB  1 
ATOM   2777 C CG  . ARG C 3 451 ? 221.285 189.981 149.183 1.00 38.88  ? 454 ARG R CG  1 
ATOM   2778 C CD  . ARG C 3 451 ? 220.232 189.886 150.240 1.00 38.88  ? 454 ARG R CD  1 
ATOM   2779 N NE  . ARG C 3 451 ? 220.436 188.704 151.057 1.00 38.88  ? 454 ARG R NE  1 
ATOM   2780 C CZ  . ARG C 3 451 ? 219.946 187.512 150.757 1.00 38.88  ? 454 ARG R CZ  1 
ATOM   2781 N NH1 . ARG C 3 451 ? 219.221 187.357 149.660 1.00 38.88  ? 454 ARG R NH1 1 
ATOM   2782 N NH2 . ARG C 3 451 ? 220.173 186.480 151.556 1.00 38.88  ? 454 ARG R NH2 1 
ATOM   2783 N N   . LEU C 3 452 ? 222.423 192.245 146.750 1.00 42.90  ? 455 LEU R N   1 
ATOM   2784 C CA  . LEU C 3 452 ? 222.257 193.378 145.853 1.00 42.90  ? 455 LEU R CA  1 
ATOM   2785 C C   . LEU C 3 452 ? 220.794 193.657 145.536 1.00 42.90  ? 455 LEU R C   1 
ATOM   2786 O O   . LEU C 3 452 ? 220.446 194.769 145.131 1.00 42.90  ? 455 LEU R O   1 
ATOM   2787 C CB  . LEU C 3 452 ? 223.045 193.135 144.569 1.00 42.90  ? 455 LEU R CB  1 
ATOM   2788 C CG  . LEU C 3 452 ? 223.327 194.365 143.718 1.00 42.90  ? 455 LEU R CG  1 
ATOM   2789 C CD1 . LEU C 3 452 ? 223.869 195.473 144.585 1.00 42.90  ? 455 LEU R CD1 1 
ATOM   2790 C CD2 . LEU C 3 452 ? 224.317 194.020 142.630 1.00 42.90  ? 455 LEU R CD2 1 
ATOM   2791 N N   . PHE C 3 453 ? 219.930 192.663 145.707 1.00 48.91  ? 456 PHE R N   1 
ATOM   2792 C CA  . PHE C 3 453 ? 218.520 192.799 145.377 1.00 48.91  ? 456 PHE R CA  1 
ATOM   2793 C C   . PHE C 3 453 ? 217.668 192.179 146.472 1.00 48.91  ? 456 PHE R C   1 
ATOM   2794 O O   . PHE C 3 453 ? 218.000 191.118 147.006 1.00 48.91  ? 456 PHE R O   1 
ATOM   2795 C CB  . PHE C 3 453 ? 218.196 192.133 144.042 1.00 48.91  ? 456 PHE R CB  1 
ATOM   2796 C CG  . PHE C 3 453 ? 218.896 192.747 142.866 1.00 48.91  ? 456 PHE R CG  1 
ATOM   2797 C CD1 . PHE C 3 453 ? 220.180 192.372 142.535 1.00 48.91  ? 456 PHE R CD1 1 
ATOM   2798 C CD2 . PHE C 3 453 ? 218.257 193.683 142.079 1.00 48.91  ? 456 PHE R CD2 1 
ATOM   2799 C CE1 . PHE C 3 453 ? 220.818 192.929 141.453 1.00 48.91  ? 456 PHE R CE1 1 
ATOM   2800 C CE2 . PHE C 3 453 ? 218.892 194.242 140.994 1.00 48.91  ? 456 PHE R CE2 1 
ATOM   2801 C CZ  . PHE C 3 453 ? 220.173 193.864 140.682 1.00 48.91  ? 456 PHE R CZ  1 
ATOM   2802 N N   . ARG C 3 454 ? 216.562 192.840 146.793 1.00 56.97  ? 457 ARG R N   1 
ATOM   2803 C CA  . ARG C 3 454 ? 215.631 192.331 147.788 1.00 56.97  ? 457 ARG R CA  1 
ATOM   2804 C C   . ARG C 3 454 ? 214.282 192.999 147.571 1.00 56.97  ? 457 ARG R C   1 
ATOM   2805 O O   . ARG C 3 454 ? 214.110 193.821 146.668 1.00 56.97  ? 457 ARG R O   1 
ATOM   2806 C CB  . ARG C 3 454 ? 216.142 192.568 149.209 1.00 56.97  ? 457 ARG R CB  1 
ATOM   2807 C CG  . ARG C 3 454 ? 215.707 191.507 150.192 1.00 56.97  ? 457 ARG R CG  1 
ATOM   2808 C CD  . ARG C 3 454 ? 216.384 191.678 151.528 1.00 56.97  ? 457 ARG R CD  1 
ATOM   2809 N NE  . ARG C 3 454 ? 216.168 190.519 152.381 1.00 56.97  ? 457 ARG R NE  1 
ATOM   2810 C CZ  . ARG C 3 454 ? 215.174 190.415 153.251 1.00 56.97  ? 457 ARG R CZ  1 
ATOM   2811 N NH1 . ARG C 3 454 ? 214.310 191.407 153.390 1.00 56.97  ? 457 ARG R NH1 1 
ATOM   2812 N NH2 . ARG C 3 454 ? 215.051 189.324 153.987 1.00 56.97  ? 457 ARG R NH2 1 
ATOM   2813 N N   . LYS C 3 455 ? 213.320 192.629 148.414 1.00 68.03  ? 458 LYS R N   1 
ATOM   2814 C CA  . LYS C 3 455 ? 211.962 193.153 148.344 1.00 68.03  ? 458 LYS R CA  1 
ATOM   2815 C C   . LYS C 3 455 ? 211.691 194.225 149.393 1.00 68.03  ? 458 LYS R C   1 
ATOM   2816 O O   . LYS C 3 455 ? 211.145 195.283 149.069 1.00 68.03  ? 458 LYS R O   1 
ATOM   2817 C CB  . LYS C 3 455 ? 210.946 192.015 148.495 1.00 68.03  ? 458 LYS R CB  1 
ATOM   2818 C CG  . LYS C 3 455 ? 211.243 190.776 147.664 1.00 68.03  ? 458 LYS R CG  1 
ATOM   2819 C CD  . LYS C 3 455 ? 212.058 189.743 148.433 1.00 68.03  ? 458 LYS R CD  1 
ATOM   2820 C CE  . LYS C 3 455 ? 212.364 188.527 147.570 1.00 68.03  ? 458 LYS R CE  1 
ATOM   2821 N NZ  . LYS C 3 455 ? 213.299 187.583 148.240 1.00 68.03  ? 458 LYS R NZ  1 
ATOM   2822 N N   . SER C 3 456 ? 212.066 193.978 150.644 1.00 66.90  ? 459 SER R N   1 
ATOM   2823 C CA  . SER C 3 456 ? 211.775 194.887 151.740 1.00 66.90  ? 459 SER R CA  1 
ATOM   2824 C C   . SER C 3 456 ? 213.027 195.110 152.573 1.00 66.90  ? 459 SER R C   1 
ATOM   2825 O O   . SER C 3 456 ? 213.907 194.252 152.652 1.00 66.90  ? 459 SER R O   1 
ATOM   2826 C CB  . SER C 3 456 ? 210.655 194.345 152.627 1.00 66.90  ? 459 SER R CB  1 
ATOM   2827 O OG  . SER C 3 456 ? 211.002 193.075 153.147 1.00 66.90  ? 459 SER R OG  1 
ATOM   2828 N N   . ASN C 3 457 ? 213.088 196.276 153.208 1.00 60.28  ? 460 ASN R N   1 
ATOM   2829 C CA  . ASN C 3 457 ? 214.255 196.648 153.993 1.00 60.28  ? 460 ASN R CA  1 
ATOM   2830 C C   . ASN C 3 457 ? 214.406 195.743 155.208 1.00 60.28  ? 460 ASN R C   1 
ATOM   2831 O O   . ASN C 3 457 ? 213.426 195.270 155.787 1.00 60.28  ? 460 ASN R O   1 
ATOM   2832 C CB  . ASN C 3 457 ? 214.151 198.103 154.438 1.00 60.28  ? 460 ASN R CB  1 
ATOM   2833 C CG  . ASN C 3 457 ? 213.683 199.015 153.327 1.00 60.28  ? 460 ASN R CG  1 
ATOM   2834 O OD1 . ASN C 3 457 ? 213.938 198.758 152.152 1.00 60.28  ? 460 ASN R OD1 1 
ATOM   2835 N ND2 . ASN C 3 457 ? 212.997 200.089 153.692 1.00 60.28  ? 460 ASN R ND2 1 
ATOM   2836 N N   . LEU C 3 458 ? 215.655 195.503 155.591 1.00 53.72  ? 461 LEU R N   1 
ATOM   2837 C CA  . LEU C 3 458 ? 215.945 194.612 156.701 1.00 53.72  ? 461 LEU R CA  1 
ATOM   2838 C C   . LEU C 3 458 ? 215.559 195.252 158.023 1.00 53.72  ? 461 LEU R C   1 
ATOM   2839 O O   . LEU C 3 458 ? 215.820 196.434 158.254 1.00 53.72  ? 461 LEU R O   1 
ATOM   2840 C CB  . LEU C 3 458 ? 217.430 194.261 156.735 1.00 53.72  ? 461 LEU R CB  1 
ATOM   2841 C CG  . LEU C 3 458 ? 218.005 193.365 155.644 1.00 53.72  ? 461 LEU R CG  1 
ATOM   2842 C CD1 . LEU C 3 458 ? 219.377 192.872 156.051 1.00 53.72  ? 461 LEU R CD1 1 
ATOM   2843 C CD2 . LEU C 3 458 ? 217.087 192.207 155.361 1.00 53.72  ? 461 LEU R CD2 1 
ATOM   2844 N N   . LYS C 3 459 ? 214.937 194.466 158.894 1.00 56.41  ? 462 LYS R N   1 
ATOM   2845 C CA  . LYS C 3 459 ? 214.857 194.864 160.285 1.00 56.41  ? 462 LYS R CA  1 
ATOM   2846 C C   . LYS C 3 459 ? 216.259 194.843 160.886 1.00 56.41  ? 462 LYS R C   1 
ATOM   2847 O O   . LYS C 3 459 ? 217.109 194.062 160.456 1.00 56.41  ? 462 LYS R O   1 
ATOM   2848 C CB  . LYS C 3 459 ? 213.943 193.935 161.080 1.00 56.41  ? 462 LYS R CB  1 
ATOM   2849 C CG  . LYS C 3 459 ? 212.462 194.274 161.015 1.00 56.41  ? 462 LYS R CG  1 
ATOM   2850 C CD  . LYS C 3 459 ? 211.815 193.808 159.729 1.00 56.41  ? 462 LYS R CD  1 
ATOM   2851 C CE  . LYS C 3 459 ? 211.705 192.291 159.716 1.00 56.41  ? 462 LYS R CE  1 
ATOM   2852 N NZ  . LYS C 3 459 ? 211.000 191.786 158.507 1.00 56.41  ? 462 LYS R NZ  1 
ATOM   2853 N N   . PRO C 3 460 ? 216.530 195.691 161.873 1.00 48.40  ? 463 PRO R N   1 
ATOM   2854 C CA  . PRO C 3 460 ? 217.882 195.749 162.436 1.00 48.40  ? 463 PRO R CA  1 
ATOM   2855 C C   . PRO C 3 460 ? 218.322 194.404 162.988 1.00 48.40  ? 463 PRO R C   1 
ATOM   2856 O O   . PRO C 3 460 ? 217.531 193.667 163.576 1.00 48.40  ? 463 PRO R O   1 
ATOM   2857 C CB  . PRO C 3 460 ? 217.757 196.798 163.545 1.00 48.40  ? 463 PRO R CB  1 
ATOM   2858 C CG  . PRO C 3 460 ? 216.302 196.916 163.803 1.00 48.40  ? 463 PRO R CG  1 
ATOM   2859 C CD  . PRO C 3 460 ? 215.643 196.682 162.493 1.00 48.40  ? 463 PRO R CD  1 
ATOM   2860 N N   . PHE C 3 461 ? 219.602 194.092 162.783 1.00 42.53  ? 464 PHE R N   1 
ATOM   2861 C CA  . PHE C 3 461 ? 220.208 192.852 163.263 1.00 42.53  ? 464 PHE R CA  1 
ATOM   2862 C C   . PHE C 3 461 ? 219.481 191.628 162.712 1.00 42.53  ? 464 PHE R C   1 
ATOM   2863 O O   . PHE C 3 461 ? 219.102 190.721 163.454 1.00 42.53  ? 464 PHE R O   1 
ATOM   2864 C CB  . PHE C 3 461 ? 220.236 192.804 164.791 1.00 42.53  ? 464 PHE R CB  1 
ATOM   2865 C CG  . PHE C 3 461 ? 221.042 193.890 165.424 1.00 42.53  ? 464 PHE R CG  1 
ATOM   2866 C CD1 . PHE C 3 461 ? 222.316 194.167 164.992 1.00 42.53  ? 464 PHE R CD1 1 
ATOM   2867 C CD2 . PHE C 3 461 ? 220.524 194.623 166.470 1.00 42.53  ? 464 PHE R CD2 1 
ATOM   2868 C CE1 . PHE C 3 461 ? 223.052 195.162 165.584 1.00 42.53  ? 464 PHE R CE1 1 
ATOM   2869 C CE2 . PHE C 3 461 ? 221.256 195.618 167.063 1.00 42.53  ? 464 PHE R CE2 1 
ATOM   2870 C CZ  . PHE C 3 461 ? 222.521 195.888 166.620 1.00 42.53  ? 464 PHE R CZ  1 
ATOM   2871 N N   . GLU C 3 462 ? 219.279 191.599 161.399 1.00 45.79  ? 465 GLU R N   1 
ATOM   2872 C CA  . GLU C 3 462 ? 218.576 190.486 160.763 1.00 45.79  ? 465 GLU R CA  1 
ATOM   2873 C C   . GLU C 3 462 ? 219.289 190.106 159.470 1.00 45.79  ? 465 GLU R C   1 
ATOM   2874 O O   . GLU C 3 462 ? 219.077 190.731 158.428 1.00 45.79  ? 465 GLU R O   1 
ATOM   2875 C CB  . GLU C 3 462 ? 217.115 190.840 160.513 1.00 45.79  ? 465 GLU R CB  1 
ATOM   2876 C CG  . GLU C 3 462 ? 216.246 189.663 160.112 1.00 45.79  ? 465 GLU R CG  1 
ATOM   2877 C CD  . GLU C 3 462 ? 215.916 189.661 158.640 1.00 45.79  ? 465 GLU R CD  1 
ATOM   2878 O OE1 . GLU C 3 462 ? 216.365 190.586 157.939 1.00 45.79  ? 465 GLU R OE1 1 
ATOM   2879 O OE2 . GLU C 3 462 ? 215.202 188.743 158.185 1.00 45.79  ? 465 GLU R OE2 1 
ATOM   2880 N N   . ARG C 3 463 ? 220.129 189.080 159.544 1.00 35.24  ? 466 ARG R N   1 
ATOM   2881 C CA  . ARG C 3 463 ? 220.783 188.517 158.375 1.00 35.24  ? 466 ARG R CA  1 
ATOM   2882 C C   . ARG C 3 463 ? 219.839 187.566 157.662 1.00 35.24  ? 466 ARG R C   1 
ATOM   2883 O O   . ARG C 3 463 ? 218.978 186.938 158.281 1.00 35.24  ? 466 ARG R O   1 
ATOM   2884 C CB  . ARG C 3 463 ? 222.050 187.762 158.770 1.00 35.24  ? 466 ARG R CB  1 
ATOM   2885 C CG  . ARG C 3 463 ? 221.785 186.591 159.694 1.00 35.24  ? 466 ARG R CG  1 
ATOM   2886 C CD  . ARG C 3 463 ? 223.062 185.978 160.232 1.00 35.24  ? 466 ARG R CD  1 
ATOM   2887 N NE  . ARG C 3 463 ? 223.635 184.984 159.339 1.00 35.24  ? 466 ARG R NE  1 
ATOM   2888 C CZ  . ARG C 3 463 ? 224.602 184.142 159.686 1.00 35.24  ? 466 ARG R CZ  1 
ATOM   2889 N NH1 . ARG C 3 463 ? 225.110 184.176 160.900 1.00 35.24  ? 466 ARG R NH1 1 
ATOM   2890 N NH2 . ARG C 3 463 ? 225.064 183.263 158.817 1.00 35.24  ? 466 ARG R NH2 1 
ATOM   2891 N N   . ASP C 3 464 ? 220.001 187.466 156.347 1.00 46.43  ? 467 ASP R N   1 
ATOM   2892 C CA  . ASP C 3 464 ? 219.311 186.439 155.586 1.00 46.43  ? 467 ASP R CA  1 
ATOM   2893 C C   . ASP C 3 464 ? 220.284 185.773 154.629 1.00 46.43  ? 467 ASP R C   1 
ATOM   2894 O O   . ASP C 3 464 ? 221.168 186.422 154.069 1.00 46.43  ? 467 ASP R O   1 
ATOM   2895 C CB  . ASP C 3 464 ? 218.085 186.993 154.843 1.00 46.43  ? 467 ASP R CB  1 
ATOM   2896 C CG  . ASP C 3 464 ? 218.432 188.043 153.811 1.00 46.43  ? 467 ASP R CG  1 
ATOM   2897 O OD1 . ASP C 3 464 ? 219.614 188.405 153.669 1.00 46.43  ? 467 ASP R OD1 1 
ATOM   2898 O OD2 . ASP C 3 464 ? 217.498 188.515 153.132 1.00 46.43  ? 467 ASP R OD2 1 
ATOM   2899 N N   . ILE C 3 465 ? 220.131 184.465 154.474 1.00 44.21  ? 468 ILE R N   1 
ATOM   2900 C CA  . ILE C 3 465 ? 221.035 183.681 153.649 1.00 44.21  ? 468 ILE R CA  1 
ATOM   2901 C C   . ILE C 3 465 ? 220.356 183.120 152.410 1.00 44.21  ? 468 ILE R C   1 
ATOM   2902 O O   . ILE C 3 465 ? 221.046 182.849 151.414 1.00 44.21  ? 468 ILE R O   1 
ATOM   2903 C CB  . ILE C 3 465 ? 221.662 182.544 154.477 1.00 44.21  ? 468 ILE R CB  1 
ATOM   2904 C CG1 . ILE C 3 465 ? 222.321 183.115 155.723 1.00 44.21  ? 468 ILE R CG1 1 
ATOM   2905 C CG2 . ILE C 3 465 ? 222.709 181.806 153.686 1.00 44.21  ? 468 ILE R CG2 1 
ATOM   2906 C CD1 . ILE C 3 465 ? 222.701 182.063 156.721 1.00 44.21  ? 468 ILE R CD1 1 
ATOM   2907 N N   . SER C 3 466 ? 219.034 182.963 152.417 1.00 49.40  ? 469 SER R N   1 
ATOM   2908 C CA  . SER C 3 466 ? 218.334 182.364 151.291 1.00 49.40  ? 469 SER R CA  1 
ATOM   2909 C C   . SER C 3 466 ? 218.613 183.141 150.015 1.00 49.40  ? 469 SER R C   1 
ATOM   2910 O O   . SER C 3 466 ? 218.517 184.370 149.987 1.00 49.40  ? 469 SER R O   1 
ATOM   2911 C CB  . SER C 3 466 ? 216.833 182.329 151.566 1.00 49.40  ? 469 SER R CB  1 
ATOM   2912 O OG  . SER C 3 466 ? 216.526 181.417 152.605 1.00 49.40  ? 469 SER R OG  1 
ATOM   2913 N N   . THR C 3 467 ? 218.949 182.416 148.957 1.00 55.44  ? 470 THR R N   1 
ATOM   2914 C CA  . THR C 3 467 ? 219.336 182.999 147.683 1.00 55.44  ? 470 THR R CA  1 
ATOM   2915 C C   . THR C 3 467 ? 218.346 182.635 146.587 1.00 55.44  ? 470 THR R C   1 
ATOM   2916 O O   . THR C 3 467 ? 218.729 182.265 145.477 1.00 55.44  ? 470 THR R O   1 
ATOM   2917 C CB  . THR C 3 467 ? 220.739 182.556 147.296 1.00 55.44  ? 470 THR R CB  1 
ATOM   2918 O OG1 . THR C 3 467 ? 220.804 181.128 147.330 1.00 55.44  ? 470 THR R OG1 1 
ATOM   2919 C CG2 . THR C 3 467 ? 221.750 183.118 148.266 1.00 55.44  ? 470 THR R CG2 1 
ATOM   2920 N N   . GLU C 3 468 ? 217.056 182.713 146.893 1.00 64.46  ? 471 GLU R N   1 
ATOM   2921 C CA  . GLU C 3 468 ? 216.046 182.517 145.867 1.00 64.46  ? 471 GLU R CA  1 
ATOM   2922 C C   . GLU C 3 468 ? 216.101 183.662 144.868 1.00 64.46  ? 471 GLU R C   1 
ATOM   2923 O O   . GLU C 3 468 ? 216.238 184.827 145.246 1.00 64.46  ? 471 GLU R O   1 
ATOM   2924 C CB  . GLU C 3 468 ? 214.656 182.420 146.493 1.00 64.46  ? 471 GLU R CB  1 
ATOM   2925 C CG  . GLU C 3 468 ? 214.568 181.652 147.822 1.00 64.46  ? 471 GLU R CG  1 
ATOM   2926 C CD  . GLU C 3 468 ? 215.126 180.229 147.793 1.00 64.46  ? 471 GLU R CD  1 
ATOM   2927 O OE1 . GLU C 3 468 ? 215.084 179.569 148.852 1.00 64.46  ? 471 GLU R OE1 1 
ATOM   2928 O OE2 . GLU C 3 468 ? 215.568 179.745 146.732 1.00 64.46  ? 471 GLU R OE2 1 
ATOM   2929 N N   . ILE C 3 469 ? 215.998 183.321 143.583 1.00 71.28  ? 472 ILE R N   1 
ATOM   2930 C CA  . ILE C 3 469 ? 216.216 184.304 142.533 1.00 71.28  ? 472 ILE R CA  1 
ATOM   2931 C C   . ILE C 3 469 ? 215.216 185.439 142.663 1.00 71.28  ? 472 ILE R C   1 
ATOM   2932 O O   . ILE C 3 469 ? 214.027 185.223 142.926 1.00 71.28  ? 472 ILE R O   1 
ATOM   2933 C CB  . ILE C 3 469 ? 216.121 183.641 141.150 1.00 71.28  ? 472 ILE R CB  1 
ATOM   2934 C CG1 . ILE C 3 469 ? 217.083 182.464 141.059 1.00 71.28  ? 472 ILE R CG1 1 
ATOM   2935 C CG2 . ILE C 3 469 ? 216.456 184.640 140.071 1.00 71.28  ? 472 ILE R CG2 1 
ATOM   2936 C CD1 . ILE C 3 469 ? 218.528 182.875 141.063 1.00 71.28  ? 472 ILE R CD1 1 
ATOM   2937 N N   . TYR C 3 470 ? 215.703 186.661 142.490 1.00 75.07  ? 473 TYR R N   1 
ATOM   2938 C CA  . TYR C 3 470 ? 214.870 187.853 142.565 1.00 75.07  ? 473 TYR R CA  1 
ATOM   2939 C C   . TYR C 3 470 ? 214.347 188.192 141.175 1.00 75.07  ? 473 TYR R C   1 
ATOM   2940 O O   . TYR C 3 470 ? 215.128 188.533 140.279 1.00 75.07  ? 473 TYR R O   1 
ATOM   2941 C CB  . TYR C 3 470 ? 215.668 189.020 143.140 1.00 75.07  ? 473 TYR R CB  1 
ATOM   2942 C CG  . TYR C 3 470 ? 215.018 190.369 142.963 1.00 75.07  ? 473 TYR R CG  1 
ATOM   2943 C CD1 . TYR C 3 470 ? 214.026 190.799 143.828 1.00 75.07  ? 473 TYR R CD1 1 
ATOM   2944 C CD2 . TYR C 3 470 ? 215.406 191.218 141.939 1.00 75.07  ? 473 TYR R CD2 1 
ATOM   2945 C CE1 . TYR C 3 470 ? 213.435 192.035 143.674 1.00 75.07  ? 473 TYR R CE1 1 
ATOM   2946 C CE2 . TYR C 3 470 ? 214.819 192.454 141.776 1.00 75.07  ? 473 TYR R CE2 1 
ATOM   2947 C CZ  . TYR C 3 470 ? 213.836 192.858 142.647 1.00 75.07  ? 473 TYR R CZ  1 
ATOM   2948 O OH  . TYR C 3 470 ? 213.250 194.090 142.488 1.00 75.07  ? 473 TYR R OH  1 
ATOM   2949 N N   . GLN C 3 471 ? 213.032 188.097 140.996 1.00 82.52  ? 474 GLN R N   1 
ATOM   2950 C CA  . GLN C 3 471 ? 212.409 188.479 139.736 1.00 82.52  ? 474 GLN R CA  1 
ATOM   2951 C C   . GLN C 3 471 ? 212.273 189.995 139.689 1.00 82.52  ? 474 GLN R C   1 
ATOM   2952 O O   . GLN C 3 471 ? 211.639 190.595 140.563 1.00 82.52  ? 474 GLN R O   1 
ATOM   2953 C CB  . GLN C 3 471 ? 211.051 187.799 139.587 1.00 82.52  ? 474 GLN R CB  1 
ATOM   2954 C CG  . GLN C 3 471 ? 210.208 187.799 140.850 1.00 82.52  ? 474 GLN R CG  1 
ATOM   2955 C CD  . GLN C 3 471 ? 208.748 187.483 140.581 1.00 82.52  ? 474 GLN R CD  1 
ATOM   2956 O OE1 . GLN C 3 471 ? 208.349 187.263 139.439 1.00 82.52  ? 474 GLN R OE1 1 
ATOM   2957 N NE2 . GLN C 3 471 ? 207.944 187.459 141.636 1.00 82.52  ? 474 GLN R NE2 1 
ATOM   2958 N N   . ALA C 3 472 ? 212.863 190.616 138.667 1.00 85.27  ? 475 ALA R N   1 
ATOM   2959 C CA  . ALA C 3 472 ? 212.919 192.072 138.612 1.00 85.27  ? 475 ALA R CA  1 
ATOM   2960 C C   . ALA C 3 472 ? 211.572 192.712 138.315 1.00 85.27  ? 475 ALA R C   1 
ATOM   2961 O O   . ALA C 3 472 ? 211.453 193.937 138.431 1.00 85.27  ? 475 ALA R O   1 
ATOM   2962 C CB  . ALA C 3 472 ? 213.940 192.522 137.566 1.00 85.27  ? 475 ALA R CB  1 
ATOM   2963 N N   . GLY C 3 473 ? 210.565 191.932 137.936 1.00 87.67  ? 476 GLY R N   1 
ATOM   2964 C CA  . GLY C 3 473 ? 209.271 192.496 137.616 1.00 87.67  ? 476 GLY R CA  1 
ATOM   2965 C C   . GLY C 3 473 ? 208.127 191.524 137.802 1.00 87.67  ? 476 GLY R C   1 
ATOM   2966 O O   . GLY C 3 473 ? 208.246 190.547 138.548 1.00 87.67  ? 476 GLY R O   1 
ATOM   2967 N N   . SER C 3 474 ? 207.008 191.784 137.124 1.00 96.64  ? 477 SER R N   1 
ATOM   2968 C CA  . SER C 3 474 ? 205.839 190.925 137.269 1.00 96.64  ? 477 SER R CA  1 
ATOM   2969 C C   . SER C 3 474 ? 206.057 189.559 136.634 1.00 96.64  ? 477 SER R C   1 
ATOM   2970 O O   . SER C 3 474 ? 205.536 188.556 137.135 1.00 96.64  ? 477 SER R O   1 
ATOM   2971 C CB  . SER C 3 474 ? 204.612 191.601 136.658 1.00 96.64  ? 477 SER R CB  1 
ATOM   2972 O OG  . SER C 3 474 ? 204.760 191.757 135.258 1.00 96.64  ? 477 SER R OG  1 
ATOM   2973 N N   . THR C 3 475 ? 206.811 189.495 135.548 1.00 100.42 ? 478 THR R N   1 
ATOM   2974 C CA  . THR C 3 475 ? 206.996 188.234 134.843 1.00 100.42 ? 478 THR R CA  1 
ATOM   2975 C C   . THR C 3 475 ? 207.827 187.263 135.674 1.00 100.42 ? 478 THR R C   1 
ATOM   2976 O O   . THR C 3 475 ? 208.936 187.610 136.099 1.00 100.42 ? 478 THR R O   1 
ATOM   2977 C CB  . THR C 3 475 ? 207.644 188.479 133.476 1.00 100.42 ? 478 THR R CB  1 
ATOM   2978 O OG1 . THR C 3 475 ? 207.882 187.227 132.820 1.00 100.42 ? 478 THR R OG1 1 
ATOM   2979 C CG2 . THR C 3 475 ? 208.944 189.269 133.594 1.00 100.42 ? 478 THR R CG2 1 
ATOM   2980 N N   . PRO C 3 476 ? 207.328 186.065 135.957 1.00 99.19  ? 479 PRO R N   1 
ATOM   2981 C CA  . PRO C 3 476 ? 208.144 185.060 136.641 1.00 99.19  ? 479 PRO R CA  1 
ATOM   2982 C C   . PRO C 3 476 ? 209.077 184.361 135.661 1.00 99.19  ? 479 PRO R C   1 
ATOM   2983 O O   . PRO C 3 476 ? 208.944 184.471 134.442 1.00 99.19  ? 479 PRO R O   1 
ATOM   2984 C CB  . PRO C 3 476 ? 207.104 184.092 137.209 1.00 99.19  ? 479 PRO R CB  1 
ATOM   2985 C CG  . PRO C 3 476 ? 205.960 184.192 136.260 1.00 99.19  ? 479 PRO R CG  1 
ATOM   2986 C CD  . PRO C 3 476 ? 205.942 185.612 135.754 1.00 99.19  ? 479 PRO R CD  1 
ATOM   2987 N N   . CYS C 3 477 ? 210.039 183.628 136.224 1.00 97.98  ? 480 CYS R N   1 
ATOM   2988 C CA  . CYS C 3 477 ? 211.041 182.961 135.402 1.00 97.98  ? 480 CYS R CA  1 
ATOM   2989 C C   . CYS C 3 477 ? 211.342 181.536 135.852 1.00 97.98  ? 480 CYS R C   1 
ATOM   2990 O O   . CYS C 3 477 ? 212.302 180.941 135.349 1.00 97.98  ? 480 CYS R O   1 
ATOM   2991 C CB  . CYS C 3 477 ? 212.337 183.777 135.376 1.00 97.98  ? 480 CYS R CB  1 
ATOM   2992 S SG  . CYS C 3 477 ? 212.963 184.239 137.003 1.00 97.98  ? 480 CYS R SG  1 
ATOM   2993 N N   . ASN C 3 478 ? 210.563 180.976 136.777 1.00 90.82  ? 481 ASN R N   1 
ATOM   2994 C CA  . ASN C 3 478 ? 210.698 179.575 137.179 1.00 90.82  ? 481 ASN R CA  1 
ATOM   2995 C C   . ASN C 3 478 ? 212.085 179.278 137.748 1.00 90.82  ? 481 ASN R C   1 
ATOM   2996 O O   . ASN C 3 478 ? 212.634 178.191 137.560 1.00 90.82  ? 481 ASN R O   1 
ATOM   2997 C CB  . ASN C 3 478 ? 210.379 178.643 136.009 1.00 90.82  ? 481 ASN R CB  1 
ATOM   2998 C CG  . ASN C 3 478 ? 209.104 179.032 135.290 1.00 90.82  ? 481 ASN R CG  1 
ATOM   2999 O OD1 . ASN C 3 478 ? 209.140 179.520 134.161 1.00 90.82  ? 481 ASN R OD1 1 
ATOM   3000 N ND2 . ASN C 3 478 ? 207.968 178.821 135.942 1.00 90.82  ? 481 ASN R ND2 1 
ATOM   3001 N N   . GLY C 3 479 ? 212.655 180.254 138.450 1.00 85.91  ? 482 GLY R N   1 
ATOM   3002 C CA  . GLY C 3 479 ? 213.901 180.047 139.164 1.00 85.91  ? 482 GLY R CA  1 
ATOM   3003 C C   . GLY C 3 479 ? 215.110 179.744 138.304 1.00 85.91  ? 482 GLY R C   1 
ATOM   3004 O O   . GLY C 3 479 ? 215.865 178.813 138.597 1.00 85.91  ? 482 GLY R O   1 
ATOM   3005 N N   . VAL C 3 480 ? 215.307 180.512 137.237 1.00 81.25  ? 483 VAL R N   1 
ATOM   3006 C CA  . VAL C 3 480 ? 216.492 180.398 136.400 1.00 81.25  ? 483 VAL R CA  1 
ATOM   3007 C C   . VAL C 3 480 ? 217.119 181.778 136.256 1.00 81.25  ? 483 VAL R C   1 
ATOM   3008 O O   . VAL C 3 480 ? 216.410 182.779 136.099 1.00 81.25  ? 483 VAL R O   1 
ATOM   3009 C CB  . VAL C 3 480 ? 216.164 179.785 135.020 1.00 81.25  ? 483 VAL R CB  1 
ATOM   3010 C CG1 . VAL C 3 480 ? 215.251 180.695 134.217 1.00 81.25  ? 483 VAL R CG1 1 
ATOM   3011 C CG2 . VAL C 3 480 ? 217.441 179.491 134.250 1.00 81.25  ? 483 VAL R CG2 1 
ATOM   3012 N N   . LYS C 3 481 ? 218.445 181.839 136.350 1.00 78.14  ? 484 LYS R N   1 
ATOM   3013 C CA  . LYS C 3 481 ? 219.148 183.097 136.138 1.00 78.14  ? 484 LYS R CA  1 
ATOM   3014 C C   . LYS C 3 481 ? 219.054 183.493 134.672 1.00 78.14  ? 484 LYS R C   1 
ATOM   3015 O O   . LYS C 3 481 ? 219.488 182.746 133.790 1.00 78.14  ? 484 LYS R O   1 
ATOM   3016 C CB  . LYS C 3 481 ? 220.607 182.981 136.573 1.00 78.14  ? 484 LYS R CB  1 
ATOM   3017 C CG  . LYS C 3 481 ? 220.794 182.726 138.059 1.00 78.14  ? 484 LYS R CG  1 
ATOM   3018 C CD  . LYS C 3 481 ? 222.269 182.691 138.446 1.00 78.14  ? 484 LYS R CD  1 
ATOM   3019 C CE  . LYS C 3 481 ? 222.974 181.456 137.924 1.00 78.14  ? 484 LYS R CE  1 
ATOM   3020 N NZ  . LYS C 3 481 ? 222.449 180.223 138.571 1.00 78.14  ? 484 LYS R NZ  1 
ATOM   3021 N N   . GLY C 3 482 ? 218.491 184.670 134.413 1.00 87.88  ? 485 GLY R N   1 
ATOM   3022 C CA  . GLY C 3 482 ? 218.285 185.121 133.052 1.00 87.88  ? 485 GLY R CA  1 
ATOM   3023 C C   . GLY C 3 482 ? 217.823 186.560 132.952 1.00 87.88  ? 485 GLY R C   1 
ATOM   3024 O O   . GLY C 3 482 ? 218.338 187.437 133.649 1.00 87.88  ? 485 GLY R O   1 
ATOM   3025 N N   . PHE C 3 483 ? 216.855 186.815 132.079 1.00 95.71  ? 486 PHE R N   1 
ATOM   3026 C CA  . PHE C 3 483 ? 216.384 188.171 131.842 1.00 95.71  ? 486 PHE R CA  1 
ATOM   3027 C C   . PHE C 3 483 ? 215.351 188.551 132.897 1.00 95.71  ? 486 PHE R C   1 
ATOM   3028 O O   . PHE C 3 483 ? 214.417 187.789 133.164 1.00 95.71  ? 486 PHE R O   1 
ATOM   3029 C CB  . PHE C 3 483 ? 215.794 188.279 130.437 1.00 95.71  ? 486 PHE R CB  1 
ATOM   3030 C CG  . PHE C 3 483 ? 215.321 189.651 130.079 1.00 95.71  ? 486 PHE R CG  1 
ATOM   3031 C CD1 . PHE C 3 483 ? 216.228 190.643 129.755 1.00 95.71  ? 486 PHE R CD1 1 
ATOM   3032 C CD2 . PHE C 3 483 ? 213.972 189.948 130.048 1.00 95.71  ? 486 PHE R CD2 1 
ATOM   3033 C CE1 . PHE C 3 483 ? 215.800 191.909 129.418 1.00 95.71  ? 486 PHE R CE1 1 
ATOM   3034 C CE2 . PHE C 3 483 ? 213.536 191.213 129.711 1.00 95.71  ? 486 PHE R CE2 1 
ATOM   3035 C CZ  . PHE C 3 483 ? 214.453 192.195 129.396 1.00 95.71  ? 486 PHE R CZ  1 
ATOM   3036 N N   . ASN C 3 484 ? 215.535 189.722 133.504 1.00 92.69  ? 487 ASN R N   1 
ATOM   3037 C CA  . ASN C 3 484 ? 214.714 190.236 134.598 1.00 92.69  ? 487 ASN R CA  1 
ATOM   3038 C C   . ASN C 3 484 ? 214.731 189.333 135.826 1.00 92.69  ? 487 ASN R C   1 
ATOM   3039 O O   . ASN C 3 484 ? 213.875 189.475 136.707 1.00 92.69  ? 487 ASN R O   1 
ATOM   3040 C CB  . ASN C 3 484 ? 213.268 190.485 134.154 1.00 92.69  ? 487 ASN R CB  1 
ATOM   3041 C CG  . ASN C 3 484 ? 213.004 191.941 133.832 1.00 92.69  ? 487 ASN R CG  1 
ATOM   3042 O OD1 . ASN C 3 484 ? 213.757 192.822 134.241 1.00 92.69  ? 487 ASN R OD1 1 
ATOM   3043 N ND2 . ASN C 3 484 ? 211.930 192.202 133.098 1.00 92.69  ? 487 ASN R ND2 1 
ATOM   3044 N N   . CYS C 3 485 ? 215.681 188.403 135.905 1.00 86.57  ? 488 CYS R N   1 
ATOM   3045 C CA  . CYS C 3 485 ? 215.895 187.576 137.086 1.00 86.57  ? 488 CYS R CA  1 
ATOM   3046 C C   . CYS C 3 485 ? 217.393 187.480 137.317 1.00 86.57  ? 488 CYS R C   1 
ATOM   3047 O O   . CYS C 3 485 ? 218.141 187.144 136.395 1.00 86.57  ? 488 CYS R O   1 
ATOM   3048 C CB  . CYS C 3 485 ? 215.283 186.186 136.910 1.00 86.57  ? 488 CYS R CB  1 
ATOM   3049 S SG  . CYS C 3 485 ? 213.485 186.188 136.780 1.00 86.57  ? 488 CYS R SG  1 
ATOM   3050 N N   . TYR C 3 486 ? 217.834 187.775 138.535 1.00 71.42  ? 489 TYR R N   1 
ATOM   3051 C CA  . TYR C 3 486 ? 219.256 187.843 138.825 1.00 71.42  ? 489 TYR R CA  1 
ATOM   3052 C C   . TYR C 3 486 ? 219.584 187.086 140.101 1.00 71.42  ? 489 TYR R C   1 
ATOM   3053 O O   . TYR C 3 486 ? 218.758 186.972 141.008 1.00 71.42  ? 489 TYR R O   1 
ATOM   3054 C CB  . TYR C 3 486 ? 219.725 189.288 138.965 1.00 71.42  ? 489 TYR R CB  1 
ATOM   3055 C CG  . TYR C 3 486 ? 219.335 190.182 137.815 1.00 71.42  ? 489 TYR R CG  1 
ATOM   3056 C CD1 . TYR C 3 486 ? 220.014 190.129 136.609 1.00 71.42  ? 489 TYR R CD1 1 
ATOM   3057 C CD2 . TYR C 3 486 ? 218.297 191.090 137.942 1.00 71.42  ? 489 TYR R CD2 1 
ATOM   3058 C CE1 . TYR C 3 486 ? 219.664 190.950 135.560 1.00 71.42  ? 489 TYR R CE1 1 
ATOM   3059 C CE2 . TYR C 3 486 ? 217.938 191.913 136.899 1.00 71.42  ? 489 TYR R CE2 1 
ATOM   3060 C CZ  . TYR C 3 486 ? 218.624 191.840 135.711 1.00 71.42  ? 489 TYR R CZ  1 
ATOM   3061 O OH  . TYR C 3 486 ? 218.266 192.662 134.669 1.00 71.42  ? 489 TYR R OH  1 
ATOM   3062 N N   . PHE C 3 487 ? 220.800 186.565 140.153 1.00 47.32  ? 490 PHE R N   1 
ATOM   3063 C CA  . PHE C 3 487 ? 221.344 186.023 141.388 1.00 47.32  ? 490 PHE R CA  1 
ATOM   3064 C C   . PHE C 3 487 ? 221.672 187.184 142.314 1.00 47.32  ? 490 PHE R C   1 
ATOM   3065 O O   . PHE C 3 487 ? 222.415 188.088 141.914 1.00 47.32  ? 490 PHE R O   1 
ATOM   3066 C CB  . PHE C 3 487 ? 222.588 185.195 141.093 1.00 47.32  ? 490 PHE R CB  1 
ATOM   3067 C CG  . PHE C 3 487 ? 222.955 184.232 142.182 1.00 47.32  ? 490 PHE R CG  1 
ATOM   3068 C CD1 . PHE C 3 487 ? 221.985 183.534 142.864 1.00 47.32  ? 490 PHE R CD1 1 
ATOM   3069 C CD2 . PHE C 3 487 ? 224.275 184.006 142.502 1.00 47.32  ? 490 PHE R CD2 1 
ATOM   3070 C CE1 . PHE C 3 487 ? 222.323 182.649 143.857 1.00 47.32  ? 490 PHE R CE1 1 
ATOM   3071 C CE2 . PHE C 3 487 ? 224.613 183.120 143.490 1.00 47.32  ? 490 PHE R CE2 1 
ATOM   3072 C CZ  . PHE C 3 487 ? 223.637 182.442 144.167 1.00 47.32  ? 490 PHE R CZ  1 
ATOM   3073 N N   . PRO C 3 488 ? 221.148 187.216 143.538 1.00 40.92  ? 491 PRO R N   1 
ATOM   3074 C CA  . PRO C 3 488 ? 221.284 188.411 144.372 1.00 40.92  ? 491 PRO R CA  1 
ATOM   3075 C C   . PRO C 3 488 ? 222.655 188.617 144.997 1.00 40.92  ? 491 PRO R C   1 
ATOM   3076 O O   . PRO C 3 488 ? 222.830 189.598 145.726 1.00 40.92  ? 491 PRO R O   1 
ATOM   3077 C CB  . PRO C 3 488 ? 220.220 188.182 145.450 1.00 40.92  ? 491 PRO R CB  1 
ATOM   3078 C CG  . PRO C 3 488 ? 220.074 186.735 145.525 1.00 40.92  ? 491 PRO R CG  1 
ATOM   3079 C CD  . PRO C 3 488 ? 220.236 186.235 144.137 1.00 40.92  ? 491 PRO R CD  1 
ATOM   3080 N N   . LEU C 3 489 ? 223.639 187.761 144.753 1.00 38.30  ? 492 LEU R N   1 
ATOM   3081 C CA  . LEU C 3 489 ? 224.955 187.902 145.368 1.00 38.30  ? 492 LEU R CA  1 
ATOM   3082 C C   . LEU C 3 489 ? 225.991 188.170 144.288 1.00 38.30  ? 492 LEU R C   1 
ATOM   3083 O O   . LEU C 3 489 ? 226.207 187.328 143.412 1.00 38.30  ? 492 LEU R O   1 
ATOM   3084 C CB  . LEU C 3 489 ? 225.325 186.645 146.155 1.00 38.30  ? 492 LEU R CB  1 
ATOM   3085 C CG  . LEU C 3 489 ? 224.812 186.515 147.585 1.00 38.30  ? 492 LEU R CG  1 
ATOM   3086 C CD1 . LEU C 3 489 ? 223.311 186.421 147.628 1.00 38.30  ? 492 LEU R CD1 1 
ATOM   3087 C CD2 . LEU C 3 489 ? 225.419 185.301 148.234 1.00 38.30  ? 492 LEU R CD2 1 
ATOM   3088 N N   . GLN C 3 490 ? 226.647 189.320 144.358 1.00 39.03  ? 493 GLN R N   1 
ATOM   3089 C CA  . GLN C 3 490 ? 227.699 189.659 143.415 1.00 39.03  ? 493 GLN R CA  1 
ATOM   3090 C C   . GLN C 3 490 ? 228.985 189.922 144.189 1.00 39.03  ? 493 GLN R C   1 
ATOM   3091 O O   . GLN C 3 490 ? 228.955 190.279 145.367 1.00 39.03  ? 493 GLN R O   1 
ATOM   3092 C CB  . GLN C 3 490 ? 227.301 190.868 142.562 1.00 39.03  ? 493 GLN R CB  1 
ATOM   3093 C CG  . GLN C 3 490 ? 228.299 191.242 141.481 1.00 39.03  ? 493 GLN R CG  1 
ATOM   3094 C CD  . GLN C 3 490 ? 227.830 192.407 140.630 1.00 39.03  ? 493 GLN R CD  1 
ATOM   3095 O OE1 . GLN C 3 490 ? 226.763 192.973 140.865 1.00 39.03  ? 493 GLN R OE1 1 
ATOM   3096 N NE2 . GLN C 3 490 ? 228.630 192.774 139.638 1.00 39.03  ? 493 GLN R NE2 1 
ATOM   3097 N N   . SER C 3 491 ? 230.120 189.734 143.525 1.00 36.70  ? 494 SER R N   1 
ATOM   3098 C CA  . SER C 3 491 ? 231.405 189.624 144.201 1.00 36.70  ? 494 SER R CA  1 
ATOM   3099 C C   . SER C 3 491 ? 232.189 190.929 144.161 1.00 36.70  ? 494 SER R C   1 
ATOM   3100 O O   . SER C 3 491 ? 232.197 191.631 143.148 1.00 36.70  ? 494 SER R O   1 
ATOM   3101 C CB  . SER C 3 491 ? 232.237 188.510 143.571 1.00 36.70  ? 494 SER R CB  1 
ATOM   3102 O OG  . SER C 3 491 ? 233.515 188.425 144.168 1.00 36.70  ? 494 SER R OG  1 
ATOM   3103 N N   . TYR C 3 492 ? 232.844 191.243 145.285 1.00 39.63  ? 495 TYR R N   1 
ATOM   3104 C CA  . TYR C 3 492 ? 233.791 192.355 145.349 1.00 39.63  ? 495 TYR R CA  1 
ATOM   3105 C C   . TYR C 3 492 ? 235.008 192.136 144.460 1.00 39.63  ? 495 TYR R C   1 
ATOM   3106 O O   . TYR C 3 492 ? 235.344 192.993 143.636 1.00 39.63  ? 495 TYR R O   1 
ATOM   3107 C CB  . TYR C 3 492 ? 234.220 192.572 146.797 1.00 39.63  ? 495 TYR R CB  1 
ATOM   3108 C CG  . TYR C 3 492 ? 233.188 193.245 147.662 1.00 39.63  ? 495 TYR R CG  1 
ATOM   3109 C CD1 . TYR C 3 492 ? 232.163 193.975 147.099 1.00 39.63  ? 495 TYR R CD1 1 
ATOM   3110 C CD2 . TYR C 3 492 ? 233.213 193.118 149.039 1.00 39.63  ? 495 TYR R CD2 1 
ATOM   3111 C CE1 . TYR C 3 492 ? 231.234 194.615 147.881 1.00 39.63  ? 495 TYR R CE1 1 
ATOM   3112 C CE2 . TYR C 3 492 ? 232.265 193.736 149.828 1.00 39.63  ? 495 TYR R CE2 1 
ATOM   3113 C CZ  . TYR C 3 492 ? 231.274 194.477 149.238 1.00 39.63  ? 495 TYR R CZ  1 
ATOM   3114 O OH  . TYR C 3 492 ? 230.321 195.102 150.001 1.00 39.63  ? 495 TYR R OH  1 
ATOM   3115 N N   . GLY C 3 493 ? 235.686 191.007 144.616 1.00 47.48  ? 496 GLY R N   1 
ATOM   3116 C CA  . GLY C 3 493 ? 236.872 190.742 143.825 1.00 47.48  ? 496 GLY R CA  1 
ATOM   3117 C C   . GLY C 3 493 ? 237.969 191.775 143.978 1.00 47.48  ? 496 GLY R C   1 
ATOM   3118 O O   . GLY C 3 493 ? 238.259 192.513 143.036 1.00 47.48  ? 496 GLY R O   1 
ATOM   3119 N N   . PHE C 3 494 ? 238.580 191.842 145.158 1.00 47.92  ? 497 PHE R N   1 
ATOM   3120 C CA  . PHE C 3 494 ? 239.627 192.822 145.414 1.00 47.92  ? 497 PHE R CA  1 
ATOM   3121 C C   . PHE C 3 494 ? 240.917 192.444 144.702 1.00 47.92  ? 497 PHE R C   1 
ATOM   3122 O O   . PHE C 3 494 ? 241.199 191.269 144.463 1.00 47.92  ? 497 PHE R O   1 
ATOM   3123 C CB  . PHE C 3 494 ? 239.910 192.929 146.908 1.00 47.92  ? 497 PHE R CB  1 
ATOM   3124 C CG  . PHE C 3 494 ? 238.694 193.137 147.745 1.00 47.92  ? 497 PHE R CG  1 
ATOM   3125 C CD1 . PHE C 3 494 ? 237.839 194.185 147.497 1.00 47.92  ? 497 PHE R CD1 1 
ATOM   3126 C CD2 . PHE C 3 494 ? 238.407 192.280 148.780 1.00 47.92  ? 497 PHE R CD2 1 
ATOM   3127 C CE1 . PHE C 3 494 ? 236.728 194.372 148.270 1.00 47.92  ? 497 PHE R CE1 1 
ATOM   3128 C CE2 . PHE C 3 494 ? 237.296 192.464 149.546 1.00 47.92  ? 497 PHE R CE2 1 
ATOM   3129 C CZ  . PHE C 3 494 ? 236.460 193.512 149.295 1.00 47.92  ? 497 PHE R CZ  1 
ATOM   3130 N N   . GLN C 3 495 ? 241.704 193.459 144.362 1.00 59.08  ? 498 GLN R N   1 
ATOM   3131 C CA  . GLN C 3 495 ? 243.087 193.292 143.943 1.00 59.08  ? 498 GLN R CA  1 
ATOM   3132 C C   . GLN C 3 495 ? 243.922 194.380 144.597 1.00 59.08  ? 498 GLN R C   1 
ATOM   3133 O O   . GLN C 3 495 ? 243.422 195.485 144.837 1.00 59.08  ? 498 GLN R O   1 
ATOM   3134 C CB  . GLN C 3 495 ? 243.251 193.350 142.415 1.00 59.08  ? 498 GLN R CB  1 
ATOM   3135 C CG  . GLN C 3 495 ? 242.426 192.328 141.664 1.00 59.08  ? 498 GLN R CG  1 
ATOM   3136 C CD  . GLN C 3 495 ? 241.889 192.851 140.352 1.00 59.08  ? 498 GLN R CD  1 
ATOM   3137 O OE1 . GLN C 3 495 ? 241.005 193.703 140.325 1.00 59.08  ? 498 GLN R OE1 1 
ATOM   3138 N NE2 . GLN C 3 495 ? 242.425 192.342 139.251 1.00 59.08  ? 498 GLN R NE2 1 
ATOM   3139 N N   . PRO C 3 496 ? 245.192 194.101 144.899 1.00 65.46  ? 499 PRO R N   1 
ATOM   3140 C CA  . PRO C 3 496 ? 246.005 195.095 145.615 1.00 65.46  ? 499 PRO R CA  1 
ATOM   3141 C C   . PRO C 3 496 ? 246.235 196.376 144.832 1.00 65.46  ? 499 PRO R C   1 
ATOM   3142 O O   . PRO C 3 496 ? 246.583 197.398 145.438 1.00 65.46  ? 499 PRO R O   1 
ATOM   3143 C CB  . PRO C 3 496 ? 247.321 194.350 145.877 1.00 65.46  ? 499 PRO R CB  1 
ATOM   3144 C CG  . PRO C 3 496 ? 247.376 193.301 144.836 1.00 65.46  ? 499 PRO R CG  1 
ATOM   3145 C CD  . PRO C 3 496 ? 245.957 192.881 144.594 1.00 65.46  ? 499 PRO R CD  1 
ATOM   3146 N N   . THR C 3 497 ? 246.047 196.365 143.515 1.00 75.34  ? 500 THR R N   1 
ATOM   3147 C CA  . THR C 3 497 ? 246.285 197.548 142.701 1.00 75.34  ? 500 THR R CA  1 
ATOM   3148 C C   . THR C 3 497 ? 245.111 198.515 142.701 1.00 75.34  ? 500 THR R C   1 
ATOM   3149 O O   . THR C 3 497 ? 245.194 199.559 142.048 1.00 75.34  ? 500 THR R O   1 
ATOM   3150 C CB  . THR C 3 497 ? 246.605 197.145 141.264 1.00 75.34  ? 500 THR R CB  1 
ATOM   3151 O OG1 . THR C 3 497 ? 245.399 196.751 140.602 1.00 75.34  ? 500 THR R OG1 1 
ATOM   3152 C CG2 . THR C 3 497 ? 247.578 195.984 141.254 1.00 75.34  ? 500 THR R CG2 1 
ATOM   3153 N N   . TYR C 3 498 ? 244.026 198.197 143.398 1.00 70.16  ? 501 TYR R N   1 
ATOM   3154 C CA  . TYR C 3 498 ? 242.898 199.107 143.486 1.00 70.16  ? 501 TYR R CA  1 
ATOM   3155 C C   . TYR C 3 498 ? 243.254 200.314 144.352 1.00 70.16  ? 501 TYR R C   1 
ATOM   3156 O O   . TYR C 3 498 ? 244.301 200.363 145.002 1.00 70.16  ? 501 TYR R O   1 
ATOM   3157 C CB  . TYR C 3 498 ? 241.681 198.389 144.064 1.00 70.16  ? 501 TYR R CB  1 
ATOM   3158 C CG  . TYR C 3 498 ? 240.903 197.571 143.063 1.00 70.16  ? 501 TYR R CG  1 
ATOM   3159 C CD1 . TYR C 3 498 ? 241.343 197.434 141.757 1.00 70.16  ? 501 TYR R CD1 1 
ATOM   3160 C CD2 . TYR C 3 498 ? 239.727 196.932 143.429 1.00 70.16  ? 501 TYR R CD2 1 
ATOM   3161 C CE1 . TYR C 3 498 ? 240.632 196.688 140.843 1.00 70.16  ? 501 TYR R CE1 1 
ATOM   3162 C CE2 . TYR C 3 498 ? 239.012 196.184 142.524 1.00 70.16  ? 501 TYR R CE2 1 
ATOM   3163 C CZ  . TYR C 3 498 ? 239.467 196.064 141.232 1.00 70.16  ? 501 TYR R CZ  1 
ATOM   3164 O OH  . TYR C 3 498 ? 238.758 195.317 140.321 1.00 70.16  ? 501 TYR R OH  1 
ATOM   3165 N N   . GLY C 3 499 ? 242.364 201.304 144.354 1.00 59.89  ? 502 GLY R N   1 
ATOM   3166 C CA  . GLY C 3 499 ? 242.532 202.465 145.199 1.00 59.89  ? 502 GLY R CA  1 
ATOM   3167 C C   . GLY C 3 499 ? 241.980 202.253 146.596 1.00 59.89  ? 502 GLY R C   1 
ATOM   3168 O O   . GLY C 3 499 ? 241.416 201.213 146.930 1.00 59.89  ? 502 GLY R O   1 
ATOM   3169 N N   . VAL C 3 500 ? 242.155 203.277 147.432 1.00 54.88  ? 503 VAL R N   1 
ATOM   3170 C CA  . VAL C 3 500 ? 241.603 203.221 148.782 1.00 54.88  ? 503 VAL R CA  1 
ATOM   3171 C C   . VAL C 3 500 ? 240.083 203.225 148.737 1.00 54.88  ? 503 VAL R C   1 
ATOM   3172 O O   . VAL C 3 500 ? 239.426 202.661 149.619 1.00 54.88  ? 503 VAL R O   1 
ATOM   3173 C CB  . VAL C 3 500 ? 242.153 204.379 149.633 1.00 54.88  ? 503 VAL R CB  1 
ATOM   3174 C CG1 . VAL C 3 500 ? 241.452 204.446 150.978 1.00 54.88  ? 503 VAL R CG1 1 
ATOM   3175 C CG2 . VAL C 3 500 ? 243.648 204.215 149.832 1.00 54.88  ? 503 VAL R CG2 1 
ATOM   3176 N N   . GLY C 3 501 ? 239.496 203.834 147.710 1.00 55.27  ? 504 GLY R N   1 
ATOM   3177 C CA  . GLY C 3 501 ? 238.054 203.823 147.564 1.00 55.27  ? 504 GLY R CA  1 
ATOM   3178 C C   . GLY C 3 501 ? 237.463 202.462 147.267 1.00 55.27  ? 504 GLY R C   1 
ATOM   3179 O O   . GLY C 3 501 ? 236.237 202.326 147.294 1.00 55.27  ? 504 GLY R O   1 
ATOM   3180 N N   . TYR C 3 502 ? 238.300 201.459 146.988 1.00 57.20  ? 505 TYR R N   1 
ATOM   3181 C CA  . TYR C 3 502 ? 237.841 200.110 146.691 1.00 57.20  ? 505 TYR R CA  1 
ATOM   3182 C C   . TYR C 3 502 ? 238.570 199.021 147.464 1.00 57.20  ? 505 TYR R C   1 
ATOM   3183 O O   . TYR C 3 502 ? 238.247 197.845 147.283 1.00 57.20  ? 505 TYR R O   1 
ATOM   3184 C CB  . TYR C 3 502 ? 237.974 199.812 145.190 1.00 57.20  ? 505 TYR R CB  1 
ATOM   3185 C CG  . TYR C 3 502 ? 236.883 200.403 144.333 1.00 57.20  ? 505 TYR R CG  1 
ATOM   3186 C CD1 . TYR C 3 502 ? 235.668 200.765 144.882 1.00 57.20  ? 505 TYR R CD1 1 
ATOM   3187 C CD2 . TYR C 3 502 ? 237.070 200.595 142.974 1.00 57.20  ? 505 TYR R CD2 1 
ATOM   3188 C CE1 . TYR C 3 502 ? 234.667 201.301 144.111 1.00 57.20  ? 505 TYR R CE1 1 
ATOM   3189 C CE2 . TYR C 3 502 ? 236.074 201.132 142.192 1.00 57.20  ? 505 TYR R CE2 1 
ATOM   3190 C CZ  . TYR C 3 502 ? 234.872 201.484 142.767 1.00 57.20  ? 505 TYR R CZ  1 
ATOM   3191 O OH  . TYR C 3 502 ? 233.869 202.022 141.998 1.00 57.20  ? 505 TYR R OH  1 
ATOM   3192 N N   . GLN C 3 503 ? 239.537 199.362 148.303 1.00 48.15  ? 506 GLN R N   1 
ATOM   3193 C CA  . GLN C 3 503 ? 240.266 198.350 149.042 1.00 48.15  ? 506 GLN R CA  1 
ATOM   3194 C C   . GLN C 3 503 ? 239.387 197.760 150.147 1.00 48.15  ? 506 GLN R C   1 
ATOM   3195 O O   . GLN C 3 503 ? 238.371 198.345 150.520 1.00 48.15  ? 506 GLN R O   1 
ATOM   3196 C CB  . GLN C 3 503 ? 241.543 198.949 149.621 1.00 48.15  ? 506 GLN R CB  1 
ATOM   3197 C CG  . GLN C 3 503 ? 242.741 198.874 148.686 1.00 48.15  ? 506 GLN R CG  1 
ATOM   3198 C CD  . GLN C 3 503 ? 244.023 199.350 149.336 1.00 48.15  ? 506 GLN R CD  1 
ATOM   3199 O OE1 . GLN C 3 503 ? 244.071 199.587 150.543 1.00 48.15  ? 506 GLN R OE1 1 
ATOM   3200 N NE2 . GLN C 3 503 ? 245.070 199.496 148.538 1.00 48.15  ? 506 GLN R NE2 1 
ATOM   3201 N N   . PRO C 3 504 ? 239.744 196.583 150.667 1.00 38.37  ? 507 PRO R N   1 
ATOM   3202 C CA  . PRO C 3 504 ? 238.892 195.923 151.668 1.00 38.37  ? 507 PRO R CA  1 
ATOM   3203 C C   . PRO C 3 504 ? 239.183 196.400 153.083 1.00 38.37  ? 507 PRO R C   1 
ATOM   3204 O O   . PRO C 3 504 ? 240.330 196.391 153.532 1.00 38.37  ? 507 PRO R O   1 
ATOM   3205 C CB  . PRO C 3 504 ? 239.253 194.447 151.509 1.00 38.37  ? 507 PRO R CB  1 
ATOM   3206 C CG  . PRO C 3 504 ? 240.654 194.480 151.074 1.00 38.37  ? 507 PRO R CG  1 
ATOM   3207 C CD  . PRO C 3 504 ? 240.813 195.688 150.200 1.00 38.37  ? 507 PRO R CD  1 
ATOM   3208 N N   . TYR C 3 505 ? 238.127 196.772 153.803 1.00 34.82  ? 508 TYR R N   1 
ATOM   3209 C CA  . TYR C 3 505 ? 238.224 197.314 155.157 1.00 34.82  ? 508 TYR R CA  1 
ATOM   3210 C C   . TYR C 3 505 ? 237.489 196.388 156.116 1.00 34.82  ? 508 TYR R C   1 
ATOM   3211 O O   . TYR C 3 505 ? 236.268 196.479 156.250 1.00 34.82  ? 508 TYR R O   1 
ATOM   3212 C CB  . TYR C 3 505 ? 237.630 198.716 155.221 1.00 34.82  ? 508 TYR R CB  1 
ATOM   3213 C CG  . TYR C 3 505 ? 238.585 199.826 154.870 1.00 34.82  ? 508 TYR R CG  1 
ATOM   3214 C CD1 . TYR C 3 505 ? 239.668 199.603 154.043 1.00 34.82  ? 508 TYR R CD1 1 
ATOM   3215 C CD2 . TYR C 3 505 ? 238.392 201.103 155.358 1.00 34.82  ? 508 TYR R CD2 1 
ATOM   3216 C CE1 . TYR C 3 505 ? 240.530 200.615 153.718 1.00 34.82  ? 508 TYR R CE1 1 
ATOM   3217 C CE2 . TYR C 3 505 ? 239.252 202.119 155.039 1.00 34.82  ? 508 TYR R CE2 1 
ATOM   3218 C CZ  . TYR C 3 505 ? 240.319 201.869 154.220 1.00 34.82  ? 508 TYR R CZ  1 
ATOM   3219 O OH  . TYR C 3 505 ? 241.178 202.888 153.901 1.00 34.82  ? 508 TYR R OH  1 
ATOM   3220 N N   . ARG C 3 506 ? 238.219 195.520 156.804 1.00 28.30  ? 509 ARG R N   1 
ATOM   3221 C CA  . ARG C 3 506 ? 237.592 194.661 157.794 1.00 28.30  ? 509 ARG R CA  1 
ATOM   3222 C C   . ARG C 3 506 ? 236.904 195.513 158.845 1.00 28.30  ? 509 ARG R C   1 
ATOM   3223 O O   . ARG C 3 506 ? 237.370 196.599 159.174 1.00 28.30  ? 509 ARG R O   1 
ATOM   3224 C CB  . ARG C 3 506 ? 238.636 193.766 158.443 1.00 28.30  ? 509 ARG R CB  1 
ATOM   3225 C CG  . ARG C 3 506 ? 239.398 192.902 157.469 1.00 28.30  ? 509 ARG R CG  1 
ATOM   3226 C CD  . ARG C 3 506 ? 240.401 192.040 158.195 1.00 28.30  ? 509 ARG R CD  1 
ATOM   3227 N NE  . ARG C 3 506 ? 240.825 190.896 157.402 1.00 28.30  ? 509 ARG R NE  1 
ATOM   3228 C CZ  . ARG C 3 506 ? 241.306 189.776 157.923 1.00 28.30  ? 509 ARG R CZ  1 
ATOM   3229 N NH1 . ARG C 3 506 ? 241.422 189.658 159.234 1.00 28.30  ? 509 ARG R NH1 1 
ATOM   3230 N NH2 . ARG C 3 506 ? 241.674 188.777 157.137 1.00 28.30  ? 509 ARG R NH2 1 
ATOM   3231 N N   . VAL C 3 507 ? 235.772 195.042 159.349 1.00 46.07  ? 510 VAL R N   1 
ATOM   3232 C CA  . VAL C 3 507 ? 234.977 195.802 160.303 1.00 46.07  ? 510 VAL R CA  1 
ATOM   3233 C C   . VAL C 3 507 ? 234.631 194.908 161.485 1.00 46.07  ? 510 VAL R C   1 
ATOM   3234 O O   . VAL C 3 507 ? 234.562 193.684 161.356 1.00 46.07  ? 510 VAL R O   1 
ATOM   3235 C CB  . VAL C 3 507 ? 233.703 196.365 159.642 1.00 46.07  ? 510 VAL R CB  1 
ATOM   3236 C CG1 . VAL C 3 507 ? 232.874 197.134 160.626 1.00 46.07  ? 510 VAL R CG1 1 
ATOM   3237 C CG2 . VAL C 3 507 ? 234.070 197.259 158.501 1.00 46.07  ? 510 VAL R CG2 1 
ATOM   3238 N N   . VAL C 3 508 ? 234.466 195.521 162.655 1.00 28.21  ? 511 VAL R N   1 
ATOM   3239 C CA  . VAL C 3 508 ? 233.920 194.868 163.839 1.00 28.21  ? 511 VAL R CA  1 
ATOM   3240 C C   . VAL C 3 508 ? 232.965 195.845 164.499 1.00 28.21  ? 511 VAL R C   1 
ATOM   3241 O O   . VAL C 3 508 ? 233.264 197.037 164.590 1.00 28.21  ? 511 VAL R O   1 
ATOM   3242 C CB  . VAL C 3 508 ? 235.014 194.448 164.832 1.00 28.21  ? 511 VAL R CB  1 
ATOM   3243 C CG1 . VAL C 3 508 ? 234.405 193.697 165.983 1.00 28.21  ? 511 VAL R CG1 1 
ATOM   3244 C CG2 . VAL C 3 508 ? 236.057 193.613 164.149 1.00 28.21  ? 511 VAL R CG2 1 
ATOM   3245 N N   . VAL C 3 509 ? 231.820 195.355 164.960 1.00 24.66  ? 512 VAL R N   1 
ATOM   3246 C CA  . VAL C 3 509 ? 230.756 196.209 165.487 1.00 24.66  ? 512 VAL R CA  1 
ATOM   3247 C C   . VAL C 3 509 ? 230.362 195.660 166.855 1.00 24.66  ? 512 VAL R C   1 
ATOM   3248 O O   . VAL C 3 509 ? 229.505 194.781 166.963 1.00 24.66  ? 512 VAL R O   1 
ATOM   3249 C CB  . VAL C 3 509 ? 229.545 196.275 164.555 1.00 24.66  ? 512 VAL R CB  1 
ATOM   3250 C CG1 . VAL C 3 509 ? 228.427 197.066 165.190 1.00 24.66  ? 512 VAL R CG1 1 
ATOM   3251 C CG2 . VAL C 3 509 ? 229.937 196.873 163.226 1.00 24.66  ? 512 VAL R CG2 1 
ATOM   3252 N N   . LEU C 3 510 ? 230.971 196.181 167.910 1.00 33.66  ? 513 LEU R N   1 
ATOM   3253 C CA  . LEU C 3 510 ? 230.593 195.753 169.247 1.00 33.66  ? 513 LEU R CA  1 
ATOM   3254 C C   . LEU C 3 510 ? 229.208 196.274 169.598 1.00 33.66  ? 513 LEU R C   1 
ATOM   3255 O O   . LEU C 3 510 ? 228.877 197.429 169.327 1.00 33.66  ? 513 LEU R O   1 
ATOM   3256 C CB  . LEU C 3 510 ? 231.603 196.245 170.274 1.00 33.66  ? 513 LEU R CB  1 
ATOM   3257 C CG  . LEU C 3 510 ? 233.024 195.713 170.177 1.00 33.66  ? 513 LEU R CG  1 
ATOM   3258 C CD1 . LEU C 3 510 ? 233.946 196.569 171.002 1.00 33.66  ? 513 LEU R CD1 1 
ATOM   3259 C CD2 . LEU C 3 510 ? 233.067 194.295 170.668 1.00 33.66  ? 513 LEU R CD2 1 
ATOM   3260 N N   . SER C 3 511 ? 228.393 195.415 170.203 1.00 44.96  ? 514 SER R N   1 
ATOM   3261 C CA  . SER C 3 511 ? 227.100 195.798 170.747 1.00 44.96  ? 514 SER R CA  1 
ATOM   3262 C C   . SER C 3 511 ? 227.100 195.569 172.249 1.00 44.96  ? 514 SER R C   1 
ATOM   3263 O O   . SER C 3 511 ? 227.666 194.592 172.741 1.00 44.96  ? 514 SER R O   1 
ATOM   3264 C CB  . SER C 3 511 ? 225.955 195.007 170.117 1.00 44.96  ? 514 SER R CB  1 
ATOM   3265 O OG  . SER C 3 511 ? 225.596 195.539 168.860 1.00 44.96  ? 514 SER R OG  1 
ATOM   3266 N N   . PHE C 3 512 ? 226.456 196.472 172.975 1.00 52.55  ? 515 PHE R N   1 
ATOM   3267 C CA  . PHE C 3 512 ? 226.393 196.390 174.423 1.00 52.55  ? 515 PHE R CA  1 
ATOM   3268 C C   . PHE C 3 512 ? 224.960 196.128 174.861 1.00 52.55  ? 515 PHE R C   1 
ATOM   3269 O O   . PHE C 3 512 ? 224.009 196.474 174.157 1.00 52.55  ? 515 PHE R O   1 
ATOM   3270 C CB  . PHE C 3 512 ? 226.920 197.670 175.077 1.00 52.55  ? 515 PHE R CB  1 
ATOM   3271 C CG  . PHE C 3 512 ? 228.387 197.906 174.854 1.00 52.55  ? 515 PHE R CG  1 
ATOM   3272 C CD1 . PHE C 3 512 ? 229.288 196.864 174.914 1.00 52.55  ? 515 PHE R CD1 1 
ATOM   3273 C CD2 . PHE C 3 512 ? 228.865 199.174 174.597 1.00 52.55  ? 515 PHE R CD2 1 
ATOM   3274 C CE1 . PHE C 3 512 ? 230.630 197.082 174.712 1.00 52.55  ? 515 PHE R CE1 1 
ATOM   3275 C CE2 . PHE C 3 512 ? 230.207 199.395 174.395 1.00 52.55  ? 515 PHE R CE2 1 
ATOM   3276 C CZ  . PHE C 3 512 ? 231.088 198.349 174.452 1.00 52.55  ? 515 PHE R CZ  1 
ATOM   3277 N N   . GLU C 3 513 ? 224.826 195.496 176.024 1.00 57.19  ? 516 GLU R N   1 
ATOM   3278 C CA  . GLU C 3 513 ? 223.537 195.133 176.609 1.00 57.19  ? 516 GLU R CA  1 
ATOM   3279 C C   . GLU C 3 513 ? 222.483 196.222 176.468 1.00 57.19  ? 516 GLU R C   1 
ATOM   3280 O O   . GLU C 3 513 ? 222.334 197.068 177.346 1.00 57.19  ? 516 GLU R O   1 
ATOM   3281 C CB  . GLU C 3 513 ? 223.715 194.799 178.090 1.00 57.19  ? 516 GLU R CB  1 
ATOM   3282 C CG  . GLU C 3 513 ? 222.501 194.163 178.745 1.00 57.19  ? 516 GLU R CG  1 
ATOM   3283 C CD  . GLU C 3 513 ? 221.748 195.119 179.646 1.00 57.19  ? 516 GLU R CD  1 
ATOM   3284 O OE1 . GLU C 3 513 ? 222.360 196.090 180.133 1.00 57.19  ? 516 GLU R OE1 1 
ATOM   3285 O OE2 . GLU C 3 513 ? 220.543 194.891 179.875 1.00 57.19  ? 516 GLU R OE2 1 
ATOM   3286 N N   . TYR D 4 28  ? 206.337 161.766 204.840 1.00 121.59 ? 28  TYR N N   1 
ATOM   3287 C CA  . TYR D 4 28  ? 206.368 161.704 206.297 1.00 121.59 ? 28  TYR N CA  1 
ATOM   3288 C C   . TYR D 4 28  ? 206.624 163.087 206.886 1.00 121.59 ? 28  TYR N C   1 
ATOM   3289 O O   . TYR D 4 28  ? 206.739 164.071 206.153 1.00 121.59 ? 28  TYR N O   1 
ATOM   3290 C CB  . TYR D 4 28  ? 207.439 160.722 206.778 1.00 121.59 ? 28  TYR N CB  1 
ATOM   3291 C CG  . TYR D 4 28  ? 207.233 159.284 206.350 1.00 121.59 ? 28  TYR N CG  1 
ATOM   3292 C CD1 . TYR D 4 28  ? 206.003 158.843 205.881 1.00 121.59 ? 28  TYR N CD1 1 
ATOM   3293 C CD2 . TYR D 4 28  ? 208.276 158.371 206.412 1.00 121.59 ? 28  TYR N CD2 1 
ATOM   3294 C CE1 . TYR D 4 28  ? 205.816 157.529 205.489 1.00 121.59 ? 28  TYR N CE1 1 
ATOM   3295 C CE2 . TYR D 4 28  ? 208.100 157.055 206.022 1.00 121.59 ? 28  TYR N CE2 1 
ATOM   3296 C CZ  . TYR D 4 28  ? 206.867 156.640 205.560 1.00 121.59 ? 28  TYR N CZ  1 
ATOM   3297 O OH  . TYR D 4 28  ? 206.690 155.333 205.172 1.00 121.59 ? 28  TYR N OH  1 
ATOM   3298 N N   . THR D 4 29  ? 206.709 163.160 208.213 1.00 114.32 ? 29  THR N N   1 
ATOM   3299 C CA  . THR D 4 29  ? 207.009 164.404 208.907 1.00 114.32 ? 29  THR N CA  1 
ATOM   3300 C C   . THR D 4 29  ? 208.041 164.129 209.987 1.00 114.32 ? 29  THR N C   1 
ATOM   3301 O O   . THR D 4 29  ? 208.170 163.001 210.470 1.00 114.32 ? 29  THR N O   1 
ATOM   3302 C CB  . THR D 4 29  ? 205.756 165.038 209.526 1.00 114.32 ? 29  THR N CB  1 
ATOM   3303 O OG1 . THR D 4 29  ? 205.194 164.145 210.497 1.00 114.32 ? 29  THR N OG1 1 
ATOM   3304 C CG2 . THR D 4 29  ? 204.718 165.358 208.458 1.00 114.32 ? 29  THR N CG2 1 
ATOM   3305 N N   . ASN D 4 30  ? 208.777 165.173 210.366 1.00 105.84 ? 30  ASN N N   1 
ATOM   3306 C CA  . ASN D 4 30  ? 209.830 165.061 211.366 1.00 105.84 ? 30  ASN N CA  1 
ATOM   3307 C C   . ASN D 4 30  ? 210.118 166.437 211.952 1.00 105.84 ? 30  ASN N C   1 
ATOM   3308 O O   . ASN D 4 30  ? 209.622 167.459 211.472 1.00 105.84 ? 30  ASN N O   1 
ATOM   3309 C CB  . ASN D 4 30  ? 211.102 164.445 210.768 1.00 105.84 ? 30  ASN N CB  1 
ATOM   3310 C CG  . ASN D 4 30  ? 211.997 163.819 211.816 1.00 105.84 ? 30  ASN N CG  1 
ATOM   3311 O OD1 . ASN D 4 30  ? 211.631 163.733 212.989 1.00 105.84 ? 30  ASN N OD1 1 
ATOM   3312 N ND2 . ASN D 4 30  ? 213.176 163.375 211.400 1.00 105.84 ? 30  ASN N ND2 1 
ATOM   3313 N N   . SER D 4 31  ? 210.929 166.450 213.008 1.00 99.84  ? 31  SER N N   1 
ATOM   3314 C CA  . SER D 4 31  ? 211.362 167.678 213.656 1.00 99.84  ? 31  SER N CA  1 
ATOM   3315 C C   . SER D 4 31  ? 212.873 167.644 213.837 1.00 99.84  ? 31  SER N C   1 
ATOM   3316 O O   . SER D 4 31  ? 213.510 166.594 213.727 1.00 99.84  ? 31  SER N O   1 
ATOM   3317 C CB  . SER D 4 31  ? 210.673 167.884 215.012 1.00 99.84  ? 31  SER N CB  1 
ATOM   3318 O OG  . SER D 4 31  ? 211.085 166.903 215.945 1.00 99.84  ? 31  SER N OG  1 
ATOM   3319 N N   . PHE D 4 32  ? 213.443 168.813 214.121 1.00 84.16  ? 32  PHE N N   1 
ATOM   3320 C CA  . PHE D 4 32  ? 214.892 168.964 214.158 1.00 84.16  ? 32  PHE N CA  1 
ATOM   3321 C C   . PHE D 4 32  ? 215.313 170.081 215.106 1.00 84.16  ? 32  PHE N C   1 
ATOM   3322 O O   . PHE D 4 32  ? 214.508 170.559 215.907 1.00 84.16  ? 32  PHE N O   1 
ATOM   3323 C CB  . PHE D 4 32  ? 215.424 169.250 212.755 1.00 84.16  ? 32  PHE N CB  1 
ATOM   3324 C CG  . PHE D 4 32  ? 214.701 170.363 212.063 1.00 84.16  ? 32  PHE N CG  1 
ATOM   3325 C CD1 . PHE D 4 32  ? 215.224 171.639 212.063 1.00 84.16  ? 32  PHE N CD1 1 
ATOM   3326 C CD2 . PHE D 4 32  ? 213.500 170.135 211.413 1.00 84.16  ? 32  PHE N CD2 1 
ATOM   3327 C CE1 . PHE D 4 32  ? 214.562 172.666 211.440 1.00 84.16  ? 32  PHE N CE1 1 
ATOM   3328 C CE2 . PHE D 4 32  ? 212.833 171.161 210.784 1.00 84.16  ? 32  PHE N CE2 1 
ATOM   3329 C CZ  . PHE D 4 32  ? 213.368 172.427 210.795 1.00 84.16  ? 32  PHE N CZ  1 
ATOM   3330 N N   . THR D 4 33  ? 216.577 170.491 215.023 1.00 77.18  ? 33  THR N N   1 
ATOM   3331 C CA  . THR D 4 33  ? 217.087 171.613 215.804 1.00 77.18  ? 33  THR N CA  1 
ATOM   3332 C C   . THR D 4 33  ? 218.051 172.463 214.986 1.00 77.18  ? 33  THR N C   1 
ATOM   3333 O O   . THR D 4 33  ? 218.685 173.380 215.520 1.00 77.18  ? 33  THR N O   1 
ATOM   3334 C CB  . THR D 4 33  ? 217.783 171.113 217.069 1.00 77.18  ? 33  THR N CB  1 
ATOM   3335 O OG1 . THR D 4 33  ? 218.125 172.228 217.900 1.00 77.18  ? 33  THR N OG1 1 
ATOM   3336 C CG2 . THR D 4 33  ? 219.050 170.345 216.712 1.00 77.18  ? 33  THR N CG2 1 
ATOM   3337 N N   . ARG D 4 34  ? 218.165 172.174 213.695 1.00 71.95  ? 34  ARG N N   1 
ATOM   3338 C CA  . ARG D 4 34  ? 219.247 172.680 212.863 1.00 71.95  ? 34  ARG N CA  1 
ATOM   3339 C C   . ARG D 4 34  ? 218.705 173.574 211.750 1.00 71.95  ? 34  ARG N C   1 
ATOM   3340 O O   . ARG D 4 34  ? 217.515 173.905 211.706 1.00 71.95  ? 34  ARG N O   1 
ATOM   3341 C CB  . ARG D 4 34  ? 220.051 171.512 212.292 1.00 71.95  ? 34  ARG N CB  1 
ATOM   3342 C CG  . ARG D 4 34  ? 219.240 170.626 211.368 1.00 71.95  ? 34  ARG N CG  1 
ATOM   3343 C CD  . ARG D 4 34  ? 220.070 169.473 210.853 1.00 71.95  ? 34  ARG N CD  1 
ATOM   3344 N NE  . ARG D 4 34  ? 220.468 168.567 211.921 1.00 71.95  ? 34  ARG N NE  1 
ATOM   3345 C CZ  . ARG D 4 34  ? 221.716 168.415 212.342 1.00 71.95  ? 34  ARG N CZ  1 
ATOM   3346 N NH1 . ARG D 4 34  ? 222.713 169.103 211.809 1.00 71.95  ? 34  ARG N NH1 1 
ATOM   3347 N NH2 . ARG D 4 34  ? 221.971 167.550 213.319 1.00 71.95  ? 34  ARG N NH2 1 
ATOM   3348 N N   . GLY D 4 35  ? 219.594 173.964 210.848 1.00 62.29  ? 35  GLY N N   1 
ATOM   3349 C CA  . GLY D 4 35  ? 219.268 174.839 209.749 1.00 62.29  ? 35  GLY N CA  1 
ATOM   3350 C C   . GLY D 4 35  ? 219.915 176.212 209.785 1.00 62.29  ? 35  GLY N C   1 
ATOM   3351 O O   . GLY D 4 35  ? 219.462 177.104 209.059 1.00 62.29  ? 35  GLY N O   1 
ATOM   3352 N N   . VAL D 4 36  ? 220.950 176.409 210.597 1.00 62.34  ? 36  VAL N N   1 
ATOM   3353 C CA  . VAL D 4 36  ? 221.576 177.714 210.771 1.00 62.34  ? 36  VAL N CA  1 
ATOM   3354 C C   . VAL D 4 36  ? 222.781 177.803 209.838 1.00 62.34  ? 36  VAL N C   1 
ATOM   3355 O O   . VAL D 4 36  ? 223.634 176.910 209.803 1.00 62.34  ? 36  VAL N O   1 
ATOM   3356 C CB  . VAL D 4 36  ? 221.960 177.970 212.235 1.00 62.34  ? 36  VAL N CB  1 
ATOM   3357 C CG1 . VAL D 4 36  ? 223.005 176.977 212.728 1.00 62.34  ? 36  VAL N CG1 1 
ATOM   3358 C CG2 . VAL D 4 36  ? 222.471 179.387 212.393 1.00 62.34  ? 36  VAL N CG2 1 
ATOM   3359 N N   . TYR D 4 37  ? 222.820 178.873 209.053 1.00 57.92  ? 37  TYR N N   1 
ATOM   3360 C CA  . TYR D 4 37  ? 223.935 179.194 208.180 1.00 57.92  ? 37  TYR N CA  1 
ATOM   3361 C C   . TYR D 4 37  ? 224.461 180.577 208.533 1.00 57.92  ? 37  TYR N C   1 
ATOM   3362 O O   . TYR D 4 37  ? 223.882 181.292 209.353 1.00 57.92  ? 37  TYR N O   1 
ATOM   3363 C CB  . TYR D 4 37  ? 223.514 179.154 206.709 1.00 57.92  ? 37  TYR N CB  1 
ATOM   3364 C CG  . TYR D 4 37  ? 222.339 180.049 206.400 1.00 57.92  ? 37  TYR N CG  1 
ATOM   3365 C CD1 . TYR D 4 37  ? 221.039 179.611 206.586 1.00 57.92  ? 37  TYR N CD1 1 
ATOM   3366 C CD2 . TYR D 4 37  ? 222.534 181.338 205.929 1.00 57.92  ? 37  TYR N CD2 1 
ATOM   3367 C CE1 . TYR D 4 37  ? 219.966 180.430 206.310 1.00 57.92  ? 37  TYR N CE1 1 
ATOM   3368 C CE2 . TYR D 4 37  ? 221.469 182.162 205.649 1.00 57.92  ? 37  TYR N CE2 1 
ATOM   3369 C CZ  . TYR D 4 37  ? 220.189 181.704 205.841 1.00 57.92  ? 37  TYR N CZ  1 
ATOM   3370 O OH  . TYR D 4 37  ? 219.128 182.528 205.562 1.00 57.92  ? 37  TYR N OH  1 
ATOM   3371 N N   . TYR D 4 38  ? 225.563 180.956 207.902 1.00 54.71  ? 38  TYR N N   1 
ATOM   3372 C CA  . TYR D 4 38  ? 226.120 182.272 208.156 1.00 54.71  ? 38  TYR N CA  1 
ATOM   3373 C C   . TYR D 4 38  ? 225.235 183.334 207.503 1.00 54.71  ? 38  TYR N C   1 
ATOM   3374 O O   . TYR D 4 38  ? 224.900 183.208 206.318 1.00 54.71  ? 38  TYR N O   1 
ATOM   3375 C CB  . TYR D 4 38  ? 227.555 182.360 207.645 1.00 54.71  ? 38  TYR N CB  1 
ATOM   3376 C CG  . TYR D 4 38  ? 228.510 181.499 208.447 1.00 54.71  ? 38  TYR N CG  1 
ATOM   3377 C CD1 . TYR D 4 38  ? 228.084 180.836 209.588 1.00 54.71  ? 38  TYR N CD1 1 
ATOM   3378 C CD2 . TYR D 4 38  ? 229.834 181.367 208.079 1.00 54.71  ? 38  TYR N CD2 1 
ATOM   3379 C CE1 . TYR D 4 38  ? 228.945 180.051 210.325 1.00 54.71  ? 38  TYR N CE1 1 
ATOM   3380 C CE2 . TYR D 4 38  ? 230.702 180.585 208.817 1.00 54.71  ? 38  TYR N CE2 1 
ATOM   3381 C CZ  . TYR D 4 38  ? 230.253 179.932 209.936 1.00 54.71  ? 38  TYR N CZ  1 
ATOM   3382 O OH  . TYR D 4 38  ? 231.118 179.155 210.664 1.00 54.71  ? 38  TYR N OH  1 
ATOM   3383 N N   . PRO D 4 39  ? 224.861 184.390 208.224 1.00 60.17  ? 39  PRO N N   1 
ATOM   3384 C CA  . PRO D 4 39  ? 223.687 185.187 207.837 1.00 60.17  ? 39  PRO N CA  1 
ATOM   3385 C C   . PRO D 4 39  ? 223.847 185.968 206.546 1.00 60.17  ? 39  PRO N C   1 
ATOM   3386 O O   . PRO D 4 39  ? 223.708 187.197 206.552 1.00 60.17  ? 39  PRO N O   1 
ATOM   3387 C CB  . PRO D 4 39  ? 223.518 186.147 209.020 1.00 60.17  ? 39  PRO N CB  1 
ATOM   3388 C CG  . PRO D 4 39  ? 224.241 185.512 210.146 1.00 60.17  ? 39  PRO N CG  1 
ATOM   3389 C CD  . PRO D 4 39  ? 225.390 184.786 209.537 1.00 60.17  ? 39  PRO N CD  1 
ATOM   3390 N N   . ASP D 4 40  ? 224.158 185.280 205.446 1.00 72.37  ? 40  ASP N N   1 
ATOM   3391 C CA  . ASP D 4 40  ? 224.242 185.893 204.123 1.00 72.37  ? 40  ASP N CA  1 
ATOM   3392 C C   . ASP D 4 40  ? 225.304 186.983 204.062 1.00 72.37  ? 40  ASP N C   1 
ATOM   3393 O O   . ASP D 4 40  ? 225.430 187.678 203.050 1.00 72.37  ? 40  ASP N O   1 
ATOM   3394 C CB  . ASP D 4 40  ? 222.883 186.468 203.707 1.00 72.37  ? 40  ASP N CB  1 
ATOM   3395 C CG  . ASP D 4 40  ? 221.923 185.402 203.217 1.00 72.37  ? 40  ASP N CG  1 
ATOM   3396 O OD1 . ASP D 4 40  ? 222.251 184.203 203.324 1.00 72.37  ? 40  ASP N OD1 1 
ATOM   3397 O OD2 . ASP D 4 40  ? 220.836 185.766 202.722 1.00 72.37  ? 40  ASP N OD2 1 
ATOM   3398 N N   . LYS D 4 41  ? 226.063 187.151 205.139 1.00 64.82  ? 41  LYS N N   1 
ATOM   3399 C CA  . LYS D 4 41  ? 227.093 188.170 205.207 1.00 64.82  ? 41  LYS N CA  1 
ATOM   3400 C C   . LYS D 4 41  ? 228.365 187.595 205.817 1.00 64.82  ? 41  LYS N C   1 
ATOM   3401 O O   . LYS D 4 41  ? 228.328 186.805 206.767 1.00 64.82  ? 41  LYS N O   1 
ATOM   3402 C CB  . LYS D 4 41  ? 226.571 189.397 205.965 1.00 64.82  ? 41  LYS N CB  1 
ATOM   3403 C CG  . LYS D 4 41  ? 226.273 189.257 207.449 1.00 64.82  ? 41  LYS N CG  1 
ATOM   3404 C CD  . LYS D 4 41  ? 225.735 190.609 207.932 1.00 64.82  ? 41  LYS N CD  1 
ATOM   3405 C CE  . LYS D 4 41  ? 225.329 190.651 209.401 1.00 64.82  ? 41  LYS N CE  1 
ATOM   3406 N NZ  . LYS D 4 41  ? 226.451 190.512 210.347 1.00 64.82  ? 41  LYS N NZ  1 
ATOM   3407 N N   . VAL D 4 42  ? 229.497 188.007 205.252 1.00 67.90  ? 42  VAL N N   1 
ATOM   3408 C CA  . VAL D 4 42  ? 230.749 187.267 205.350 1.00 67.90  ? 42  VAL N CA  1 
ATOM   3409 C C   . VAL D 4 42  ? 231.669 187.935 206.359 1.00 67.90  ? 42  VAL N C   1 
ATOM   3410 O O   . VAL D 4 42  ? 232.897 187.838 206.258 1.00 67.90  ? 42  VAL N O   1 
ATOM   3411 C CB  . VAL D 4 42  ? 231.429 187.168 203.973 1.00 67.90  ? 42  VAL N CB  1 
ATOM   3412 C CG1 . VAL D 4 42  ? 230.652 186.233 203.064 1.00 67.90  ? 42  VAL N CG1 1 
ATOM   3413 C CG2 . VAL D 4 42  ? 231.537 188.549 203.342 1.00 67.90  ? 42  VAL N CG2 1 
ATOM   3414 N N   . PHE D 4 43  ? 231.083 188.618 207.332 1.00 65.71  ? 43  PHE N N   1 
ATOM   3415 C CA  . PHE D 4 43  ? 231.840 189.287 208.375 1.00 65.71  ? 43  PHE N CA  1 
ATOM   3416 C C   . PHE D 4 43  ? 232.351 188.242 209.353 1.00 65.71  ? 43  PHE N C   1 
ATOM   3417 O O   . PHE D 4 43  ? 231.742 187.182 209.519 1.00 65.71  ? 43  PHE N O   1 
ATOM   3418 C CB  . PHE D 4 43  ? 230.957 190.283 209.122 1.00 65.71  ? 43  PHE N CB  1 
ATOM   3419 C CG  . PHE D 4 43  ? 230.040 189.633 210.119 1.00 65.71  ? 43  PHE N CG  1 
ATOM   3420 C CD1 . PHE D 4 43  ? 229.039 188.774 209.704 1.00 65.71  ? 43  PHE N CD1 1 
ATOM   3421 C CD2 . PHE D 4 43  ? 230.156 189.915 211.469 1.00 65.71  ? 43  PHE N CD2 1 
ATOM   3422 C CE1 . PHE D 4 43  ? 228.205 188.165 210.624 1.00 65.71  ? 43  PHE N CE1 1 
ATOM   3423 C CE2 . PHE D 4 43  ? 229.306 189.333 212.389 1.00 65.71  ? 43  PHE N CE2 1 
ATOM   3424 C CZ  . PHE D 4 43  ? 228.331 188.459 211.968 1.00 65.71  ? 43  PHE N CZ  1 
ATOM   3425 N N   . ARG D 4 44  ? 233.480 188.531 209.982 1.00 69.82  ? 44  ARG N N   1 
ATOM   3426 C CA  . ARG D 4 44  ? 233.858 187.781 211.167 1.00 69.82  ? 44  ARG N CA  1 
ATOM   3427 C C   . ARG D 4 44  ? 233.384 188.529 212.406 1.00 69.82  ? 44  ARG N C   1 
ATOM   3428 O O   . ARG D 4 44  ? 233.356 189.764 212.425 1.00 69.82  ? 44  ARG N O   1 
ATOM   3429 C CB  . ARG D 4 44  ? 235.363 187.585 211.253 1.00 69.82  ? 44  ARG N CB  1 
ATOM   3430 C CG  . ARG D 4 44  ? 235.746 186.716 212.434 1.00 69.82  ? 44  ARG N CG  1 
ATOM   3431 C CD  . ARG D 4 44  ? 236.998 187.258 213.009 1.00 69.82  ? 44  ARG N CD  1 
ATOM   3432 N NE  . ARG D 4 44  ? 238.176 187.001 212.202 1.00 69.82  ? 44  ARG N NE  1 
ATOM   3433 C CZ  . ARG D 4 44  ? 239.247 187.773 212.255 1.00 69.82  ? 44  ARG N CZ  1 
ATOM   3434 N NH1 . ARG D 4 44  ? 239.200 188.956 212.838 1.00 69.82  ? 44  ARG N NH1 1 
ATOM   3435 N NH2 . ARG D 4 44  ? 240.366 187.378 211.652 1.00 69.82  ? 44  ARG N NH2 1 
ATOM   3436 N N   . SER D 4 45  ? 233.007 187.780 213.434 1.00 54.41  ? 45  SER N N   1 
ATOM   3437 C CA  . SER D 4 45  ? 232.802 188.328 214.763 1.00 54.41  ? 45  SER N CA  1 
ATOM   3438 C C   . SER D 4 45  ? 233.220 187.284 215.783 1.00 54.41  ? 45  SER N C   1 
ATOM   3439 O O   . SER D 4 45  ? 233.315 186.093 215.473 1.00 54.41  ? 45  SER N O   1 
ATOM   3440 C CB  . SER D 4 45  ? 231.350 188.749 214.995 1.00 54.41  ? 45  SER N CB  1 
ATOM   3441 O OG  . SER D 4 45  ? 230.467 187.688 214.694 1.00 54.41  ? 45  SER N OG  1 
ATOM   3442 N N   . HIS D 4 49  ? 225.490 187.908 218.014 1.00 49.52  ? 49  HIS N N   1 
ATOM   3443 C CA  . HIS D 4 49  ? 224.946 188.845 217.046 1.00 49.52  ? 49  HIS N CA  1 
ATOM   3444 C C   . HIS D 4 49  ? 223.509 188.458 216.722 1.00 49.52  ? 49  HIS N C   1 
ATOM   3445 O O   . HIS D 4 49  ? 223.133 187.285 216.779 1.00 49.52  ? 49  HIS N O   1 
ATOM   3446 C CB  . HIS D 4 49  ? 225.794 188.893 215.770 1.00 49.52  ? 49  HIS N CB  1 
ATOM   3447 C CG  . HIS D 4 49  ? 225.308 189.884 214.760 1.00 49.52  ? 49  HIS N CG  1 
ATOM   3448 N ND1 . HIS D 4 49  ? 225.113 191.215 215.056 1.00 49.52  ? 49  HIS N ND1 1 
ATOM   3449 C CD2 . HIS D 4 49  ? 224.980 189.739 213.454 1.00 49.52  ? 49  HIS N CD2 1 
ATOM   3450 C CE1 . HIS D 4 49  ? 224.688 191.847 213.977 1.00 49.52  ? 49  HIS N CE1 1 
ATOM   3451 N NE2 . HIS D 4 49  ? 224.597 190.973 212.992 1.00 49.52  ? 49  HIS N NE2 1 
ATOM   3452 N N   . SER D 4 50  ? 222.709 189.465 216.375 1.00 49.73  ? 50  SER N N   1 
ATOM   3453 C CA  . SER D 4 50  ? 221.300 189.291 216.055 1.00 49.73  ? 50  SER N CA  1 
ATOM   3454 C C   . SER D 4 50  ? 221.053 189.639 214.595 1.00 49.73  ? 50  SER N C   1 
ATOM   3455 O O   . SER D 4 50  ? 221.487 190.692 214.117 1.00 49.73  ? 50  SER N O   1 
ATOM   3456 C CB  . SER D 4 50  ? 220.422 190.160 216.957 1.00 49.73  ? 50  SER N CB  1 
ATOM   3457 O OG  . SER D 4 50  ? 219.052 190.011 216.634 1.00 49.73  ? 50  SER N OG  1 
ATOM   3458 N N   . THR D 4 51  ? 220.350 188.753 213.888 1.00 54.07  ? 51  THR N N   1 
ATOM   3459 C CA  . THR D 4 51  ? 220.091 188.920 212.463 1.00 54.07  ? 51  THR N CA  1 
ATOM   3460 C C   . THR D 4 51  ? 218.617 188.685 212.173 1.00 54.07  ? 51  THR N C   1 
ATOM   3461 O O   . THR D 4 51  ? 218.026 187.733 212.685 1.00 54.07  ? 51  THR N O   1 
ATOM   3462 C CB  . THR D 4 51  ? 220.932 187.948 211.625 1.00 54.07  ? 51  THR N CB  1 
ATOM   3463 O OG1 . THR D 4 51  ? 220.605 186.600 211.988 1.00 54.07  ? 51  THR N OG1 1 
ATOM   3464 C CG2 . THR D 4 51  ? 222.412 188.181 211.853 1.00 54.07  ? 51  THR N CG2 1 
ATOM   3465 N N   . GLN D 4 52  ? 218.030 189.557 211.350 1.00 60.75  ? 52  GLN N N   1 
ATOM   3466 C CA  . GLN D 4 52  ? 216.675 189.362 210.841 1.00 60.75  ? 52  GLN N CA  1 
ATOM   3467 C C   . GLN D 4 52  ? 216.783 188.911 209.386 1.00 60.75  ? 52  GLN N C   1 
ATOM   3468 O O   . GLN D 4 52  ? 216.710 189.707 208.450 1.00 60.75  ? 52  GLN N O   1 
ATOM   3469 C CB  . GLN D 4 52  ? 215.850 190.638 210.985 1.00 60.75  ? 52  GLN N CB  1 
ATOM   3470 C CG  . GLN D 4 52  ? 214.354 190.433 210.800 1.00 60.75  ? 52  GLN N CG  1 
ATOM   3471 C CD  . GLN D 4 52  ? 213.904 190.649 209.370 1.00 60.75  ? 52  GLN N CD  1 
ATOM   3472 O OE1 . GLN D 4 52  ? 214.473 191.463 208.642 1.00 60.75  ? 52  GLN N OE1 1 
ATOM   3473 N NE2 . GLN D 4 52  ? 212.870 189.923 208.957 1.00 60.75  ? 52  GLN N NE2 1 
ATOM   3474 N N   . ASP D 4 53  ? 216.965 187.611 209.204 1.00 63.45  ? 53  ASP N N   1 
ATOM   3475 C CA  . ASP D 4 53  ? 217.162 187.021 207.888 1.00 63.45  ? 53  ASP N CA  1 
ATOM   3476 C C   . ASP D 4 53  ? 216.183 185.864 207.687 1.00 63.45  ? 53  ASP N C   1 
ATOM   3477 O O   . ASP D 4 53  ? 215.338 185.582 208.539 1.00 63.45  ? 53  ASP N O   1 
ATOM   3478 C CB  . ASP D 4 53  ? 218.615 186.568 207.721 1.00 63.45  ? 53  ASP N CB  1 
ATOM   3479 C CG  . ASP D 4 53  ? 219.083 186.623 206.281 1.00 63.45  ? 53  ASP N CG  1 
ATOM   3480 O OD1 . ASP D 4 53  ? 218.232 186.521 205.372 1.00 63.45  ? 53  ASP N OD1 1 
ATOM   3481 O OD2 . ASP D 4 53  ? 220.303 186.764 206.056 1.00 63.45  ? 53  ASP N OD2 1 
ATOM   3482 N N   . LEU D 4 54  ? 216.307 185.194 206.546 1.00 61.73  ? 54  LEU N N   1 
ATOM   3483 C CA  . LEU D 4 54  ? 215.479 184.039 206.220 1.00 61.73  ? 54  LEU N CA  1 
ATOM   3484 C C   . LEU D 4 54  ? 216.106 182.807 206.863 1.00 61.73  ? 54  LEU N C   1 
ATOM   3485 O O   . LEU D 4 54  ? 217.177 182.359 206.450 1.00 61.73  ? 54  LEU N O   1 
ATOM   3486 C CB  . LEU D 4 54  ? 215.357 183.866 204.710 1.00 61.73  ? 54  LEU N CB  1 
ATOM   3487 C CG  . LEU D 4 54  ? 214.331 184.725 203.968 1.00 61.73  ? 54  LEU N CG  1 
ATOM   3488 C CD1 . LEU D 4 54  ? 214.780 186.172 203.874 1.00 61.73  ? 54  LEU N CD1 1 
ATOM   3489 C CD2 . LEU D 4 54  ? 214.084 184.156 202.586 1.00 61.73  ? 54  LEU N CD2 1 
ATOM   3490 N N   . PHE D 4 55  ? 215.438 182.260 207.874 1.00 59.03  ? 55  PHE N N   1 
ATOM   3491 C CA  . PHE D 4 55  ? 215.968 181.137 208.627 1.00 59.03  ? 55  PHE N CA  1 
ATOM   3492 C C   . PHE D 4 55  ? 214.934 180.027 208.724 1.00 59.03  ? 55  PHE N C   1 
ATOM   3493 O O   . PHE D 4 55  ? 213.778 180.178 208.318 1.00 59.03  ? 55  PHE N O   1 
ATOM   3494 C CB  . PHE D 4 55  ? 216.402 181.558 210.033 1.00 59.03  ? 55  PHE N CB  1 
ATOM   3495 C CG  . PHE D 4 55  ? 217.691 182.322 210.067 1.00 59.03  ? 55  PHE N CG  1 
ATOM   3496 C CD1 . PHE D 4 55  ? 218.893 181.684 209.821 1.00 59.03  ? 55  PHE N CD1 1 
ATOM   3497 C CD2 . PHE D 4 55  ? 217.701 183.675 210.350 1.00 59.03  ? 55  PHE N CD2 1 
ATOM   3498 C CE1 . PHE D 4 55  ? 220.082 182.383 209.855 1.00 59.03  ? 55  PHE N CE1 1 
ATOM   3499 C CE2 . PHE D 4 55  ? 218.885 184.377 210.386 1.00 59.03  ? 55  PHE N CE2 1 
ATOM   3500 C CZ  . PHE D 4 55  ? 220.077 183.731 210.137 1.00 59.03  ? 55  PHE N CZ  1 
ATOM   3501 N N   . LEU D 4 56  ? 215.370 178.916 209.262 1.00 67.90  ? 56  LEU N N   1 
ATOM   3502 C CA  . LEU D 4 56  ? 214.572 177.713 209.444 1.00 67.90  ? 56  LEU N CA  1 
ATOM   3503 C C   . LEU D 4 56  ? 214.206 177.550 210.915 1.00 67.90  ? 56  LEU N C   1 
ATOM   3504 O O   . LEU D 4 56  ? 215.106 177.436 211.755 1.00 67.90  ? 56  LEU N O   1 
ATOM   3505 C CB  . LEU D 4 56  ? 215.342 176.495 208.958 1.00 67.90  ? 56  LEU N CB  1 
ATOM   3506 C CG  . LEU D 4 56  ? 214.673 175.127 208.993 1.00 67.90  ? 56  LEU N CG  1 
ATOM   3507 C CD1 . LEU D 4 56  ? 213.455 175.091 208.095 1.00 67.90  ? 56  LEU N CD1 1 
ATOM   3508 C CD2 . LEU D 4 56  ? 215.678 174.076 208.569 1.00 67.90  ? 56  LEU N CD2 1 
ATOM   3509 N N   . PRO D 4 57  ? 212.917 177.551 211.261 1.00 69.58  ? 57  PRO N N   1 
ATOM   3510 C CA  . PRO D 4 57  ? 212.531 177.418 212.670 1.00 69.58  ? 57  PRO N CA  1 
ATOM   3511 C C   . PRO D 4 57  ? 213.072 176.133 213.275 1.00 69.58  ? 57  PRO N C   1 
ATOM   3512 O O   . PRO D 4 57  ? 213.130 175.090 212.622 1.00 69.58  ? 57  PRO N O   1 
ATOM   3513 C CB  . PRO D 4 57  ? 211.000 177.417 212.620 1.00 69.58  ? 57  PRO N CB  1 
ATOM   3514 C CG  . PRO D 4 57  ? 210.665 178.105 211.334 1.00 69.58  ? 57  PRO N CG  1 
ATOM   3515 C CD  . PRO D 4 57  ? 211.749 177.717 210.379 1.00 69.58  ? 57  PRO N CD  1 
ATOM   3516 N N   . PHE D 4 58  ? 213.471 176.222 214.546 1.00 68.35  ? 58  PHE N N   1 
ATOM   3517 C CA  . PHE D 4 58  ? 214.260 175.164 215.168 1.00 68.35  ? 58  PHE N CA  1 
ATOM   3518 C C   . PHE D 4 58  ? 213.508 173.840 215.219 1.00 68.35  ? 58  PHE N C   1 
ATOM   3519 O O   . PHE D 4 58  ? 213.895 172.873 214.553 1.00 68.35  ? 58  PHE N O   1 
ATOM   3520 C CB  . PHE D 4 58  ? 214.681 175.594 216.572 1.00 68.35  ? 58  PHE N CB  1 
ATOM   3521 C CG  . PHE D 4 58  ? 215.888 176.477 216.592 1.00 68.35  ? 58  PHE N CG  1 
ATOM   3522 C CD1 . PHE D 4 58  ? 216.392 176.959 217.786 1.00 68.35  ? 58  PHE N CD1 1 
ATOM   3523 C CD2 . PHE D 4 58  ? 216.520 176.825 215.413 1.00 68.35  ? 58  PHE N CD2 1 
ATOM   3524 C CE1 . PHE D 4 58  ? 217.503 177.771 217.802 1.00 68.35  ? 58  PHE N CE1 1 
ATOM   3525 C CE2 . PHE D 4 58  ? 217.632 177.634 215.423 1.00 68.35  ? 58  PHE N CE2 1 
ATOM   3526 C CZ  . PHE D 4 58  ? 218.122 178.109 216.618 1.00 68.35  ? 58  PHE N CZ  1 
ATOM   3527 N N   . PHE D 4 59  ? 212.434 173.774 215.995 1.00 73.32  ? 59  PHE N N   1 
ATOM   3528 C CA  . PHE D 4 59  ? 211.594 172.584 216.065 1.00 73.32  ? 59  PHE N CA  1 
ATOM   3529 C C   . PHE D 4 59  ? 210.381 172.787 215.164 1.00 73.32  ? 59  PHE N C   1 
ATOM   3530 O O   . PHE D 4 59  ? 209.263 173.036 215.616 1.00 73.32  ? 59  PHE N O   1 
ATOM   3531 C CB  . PHE D 4 59  ? 211.195 172.293 217.515 1.00 73.32  ? 59  PHE N CB  1 
ATOM   3532 C CG  . PHE D 4 59  ? 212.340 172.359 218.484 1.00 73.32  ? 59  PHE N CG  1 
ATOM   3533 C CD1 . PHE D 4 59  ? 213.206 171.289 218.623 1.00 73.32  ? 59  PHE N CD1 1 
ATOM   3534 C CD2 . PHE D 4 59  ? 212.556 173.488 219.250 1.00 73.32  ? 59  PHE N CD2 1 
ATOM   3535 C CE1 . PHE D 4 59  ? 214.261 171.341 219.510 1.00 73.32  ? 59  PHE N CE1 1 
ATOM   3536 C CE2 . PHE D 4 59  ? 213.612 173.547 220.139 1.00 73.32  ? 59  PHE N CE2 1 
ATOM   3537 C CZ  . PHE D 4 59  ? 214.465 172.473 220.268 1.00 73.32  ? 59  PHE N CZ  1 
ATOM   3538 N N   . SER D 4 60  ? 210.620 172.673 213.863 1.00 84.65  ? 60  SER N N   1 
ATOM   3539 C CA  . SER D 4 60  ? 209.604 172.880 212.844 1.00 84.65  ? 60  SER N CA  1 
ATOM   3540 C C   . SER D 4 60  ? 209.283 171.569 212.142 1.00 84.65  ? 60  SER N C   1 
ATOM   3541 O O   . SER D 4 60  ? 209.976 170.558 212.297 1.00 84.65  ? 60  SER N O   1 
ATOM   3542 C CB  . SER D 4 60  ? 210.060 173.933 211.828 1.00 84.65  ? 60  SER N CB  1 
ATOM   3543 O OG  . SER D 4 60  ? 209.013 174.256 210.930 1.00 84.65  ? 60  SER N OG  1 
ATOM   3544 N N   . ASN D 4 61  ? 208.210 171.602 211.356 1.00 98.45  ? 61  ASN N N   1 
ATOM   3545 C CA  . ASN D 4 61  ? 207.774 170.431 210.612 1.00 98.45  ? 61  ASN N CA  1 
ATOM   3546 C C   . ASN D 4 61  ? 208.593 170.294 209.333 1.00 98.45  ? 61  ASN N C   1 
ATOM   3547 O O   . ASN D 4 61  ? 208.502 171.132 208.433 1.00 98.45  ? 61  ASN N O   1 
ATOM   3548 C CB  . ASN D 4 61  ? 206.284 170.542 210.284 1.00 98.45  ? 61  ASN N CB  1 
ATOM   3549 C CG  . ASN D 4 61  ? 205.716 169.260 209.704 1.00 98.45  ? 61  ASN N CG  1 
ATOM   3550 O OD1 . ASN D 4 61  ? 206.414 168.255 209.578 1.00 98.45  ? 61  ASN N OD1 1 
ATOM   3551 N ND2 . ASN D 4 61  ? 204.438 169.292 209.346 1.00 98.45  ? 61  ASN N ND2 1 
ATOM   3552 N N   . VAL D 4 62  ? 209.393 169.232 209.256 1.00 103.97 ? 62  VAL N N   1 
ATOM   3553 C CA  . VAL D 4 62  ? 210.176 168.930 208.068 1.00 103.97 ? 62  VAL N CA  1 
ATOM   3554 C C   . VAL D 4 62  ? 209.632 167.639 207.465 1.00 103.97 ? 62  VAL N C   1 
ATOM   3555 O O   . VAL D 4 62  ? 209.179 166.733 208.171 1.00 103.97 ? 62  VAL N O   1 
ATOM   3556 C CB  . VAL D 4 62  ? 211.689 168.817 208.370 1.00 103.97 ? 62  VAL N CB  1 
ATOM   3557 C CG1 . VAL D 4 62  ? 211.979 167.639 209.283 1.00 103.97 ? 62  VAL N CG1 1 
ATOM   3558 C CG2 . VAL D 4 62  ? 212.498 168.727 207.085 1.00 103.97 ? 62  VAL N CG2 1 
ATOM   3559 N N   . THR D 4 63  ? 209.667 167.573 206.139 1.00 105.80 ? 63  THR N N   1 
ATOM   3560 C CA  . THR D 4 63  ? 208.994 166.521 205.383 1.00 105.80 ? 63  THR N CA  1 
ATOM   3561 C C   . THR D 4 63  ? 209.994 165.439 204.982 1.00 105.80 ? 63  THR N C   1 
ATOM   3562 O O   . THR D 4 63  ? 210.769 165.583 204.033 1.00 105.80 ? 63  THR N O   1 
ATOM   3563 C CB  . THR D 4 63  ? 208.297 167.127 204.164 1.00 105.80 ? 63  THR N CB  1 
ATOM   3564 O OG1 . THR D 4 63  ? 209.247 167.876 203.400 1.00 105.80 ? 63  THR N OG1 1 
ATOM   3565 C CG2 . THR D 4 63  ? 207.171 168.048 204.600 1.00 105.80 ? 63  THR N CG2 1 
ATOM   3566 N N   . TRP D 4 64  ? 209.969 164.337 205.732 1.00 111.92 ? 64  TRP N N   1 
ATOM   3567 C CA  . TRP D 4 64  ? 210.714 163.130 205.394 1.00 111.92 ? 64  TRP N CA  1 
ATOM   3568 C C   . TRP D 4 64  ? 210.151 162.534 204.107 1.00 111.92 ? 64  TRP N C   1 
ATOM   3569 O O   . TRP D 4 64  ? 208.952 162.252 204.025 1.00 111.92 ? 64  TRP N O   1 
ATOM   3570 C CB  . TRP D 4 64  ? 210.628 162.128 206.550 1.00 111.92 ? 64  TRP N CB  1 
ATOM   3571 C CG  . TRP D 4 64  ? 211.519 160.915 206.460 1.00 111.92 ? 64  TRP N CG  1 
ATOM   3572 C CD1 . TRP D 4 64  ? 211.902 160.252 205.330 1.00 111.92 ? 64  TRP N CD1 1 
ATOM   3573 C CD2 . TRP D 4 64  ? 212.093 160.195 207.560 1.00 111.92 ? 64  TRP N CD2 1 
ATOM   3574 N NE1 . TRP D 4 64  ? 212.700 159.180 205.655 1.00 111.92 ? 64  TRP N NE1 1 
ATOM   3575 C CE2 . TRP D 4 64  ? 212.831 159.123 207.018 1.00 111.92 ? 64  TRP N CE2 1 
ATOM   3576 C CE3 . TRP D 4 64  ? 212.066 160.359 208.948 1.00 111.92 ? 64  TRP N CE3 1 
ATOM   3577 C CZ2 . TRP D 4 64  ? 213.533 158.220 207.816 1.00 111.92 ? 64  TRP N CZ2 1 
ATOM   3578 C CZ3 . TRP D 4 64  ? 212.766 159.463 209.738 1.00 111.92 ? 64  TRP N CZ3 1 
ATOM   3579 C CH2 . TRP D 4 64  ? 213.487 158.407 209.170 1.00 111.92 ? 64  TRP N CH2 1 
ATOM   3580 N N   . PHE D 4 65  ? 211.001 162.331 203.103 1.00 108.74 ? 65  PHE N N   1 
ATOM   3581 C CA  . PHE D 4 65  ? 210.585 161.804 201.811 1.00 108.74 ? 65  PHE N CA  1 
ATOM   3582 C C   . PHE D 4 65  ? 211.304 160.504 201.494 1.00 108.74 ? 65  PHE N C   1 
ATOM   3583 O O   . PHE D 4 65  ? 212.416 160.260 201.974 1.00 108.74 ? 65  PHE N O   1 
ATOM   3584 C CB  . PHE D 4 65  ? 210.846 162.805 200.679 1.00 108.74 ? 65  PHE N CB  1 
ATOM   3585 C CG  . PHE D 4 65  ? 209.866 163.932 200.626 1.00 108.74 ? 65  PHE N CG  1 
ATOM   3586 C CD1 . PHE D 4 65  ? 208.562 163.712 200.218 1.00 108.74 ? 65  PHE N CD1 1 
ATOM   3587 C CD2 . PHE D 4 65  ? 210.245 165.211 200.972 1.00 108.74 ? 65  PHE N CD2 1 
ATOM   3588 C CE1 . PHE D 4 65  ? 207.655 164.749 200.162 1.00 108.74 ? 65  PHE N CE1 1 
ATOM   3589 C CE2 . PHE D 4 65  ? 209.345 166.249 200.918 1.00 108.74 ? 65  PHE N CE2 1 
ATOM   3590 C CZ  . PHE D 4 65  ? 208.049 166.020 200.513 1.00 108.74 ? 65  PHE N CZ  1 
ATOM   3591 N N   . HIS D 4 66  ? 210.659 159.679 200.677 1.00 118.36 ? 66  HIS N N   1 
ATOM   3592 C CA  . HIS D 4 66  ? 211.269 158.475 200.128 1.00 118.36 ? 66  HIS N CA  1 
ATOM   3593 C C   . HIS D 4 66  ? 211.011 158.390 198.629 1.00 118.36 ? 66  HIS N C   1 
ATOM   3594 O O   . HIS D 4 66  ? 210.221 159.160 198.083 1.00 118.36 ? 66  HIS N O   1 
ATOM   3595 C CB  . HIS D 4 66  ? 210.737 157.223 200.829 1.00 118.36 ? 66  HIS N CB  1 
ATOM   3596 C CG  . HIS D 4 66  ? 211.525 156.826 202.035 1.00 118.36 ? 66  HIS N CG  1 
ATOM   3597 N ND1 . HIS D 4 66  ? 212.795 156.300 201.952 1.00 118.36 ? 66  HIS N ND1 1 
ATOM   3598 C CD2 . HIS D 4 66  ? 211.223 156.870 203.354 1.00 118.36 ? 66  HIS N CD2 1 
ATOM   3599 C CE1 . HIS D 4 66  ? 213.244 156.041 203.168 1.00 118.36 ? 66  HIS N CE1 1 
ATOM   3600 N NE2 . HIS D 4 66  ? 212.307 156.377 204.038 1.00 118.36 ? 66  HIS N NE2 1 
ATOM   3601 N N   . ASN D 4 81  ? 210.206 161.495 194.489 1.00 103.84 ? 81  ASN N N   1 
ATOM   3602 C CA  . ASN D 4 81  ? 210.704 162.704 193.840 1.00 103.84 ? 81  ASN N CA  1 
ATOM   3603 C C   . ASN D 4 81  ? 209.574 163.546 193.258 1.00 103.84 ? 81  ASN N C   1 
ATOM   3604 O O   . ASN D 4 81  ? 209.408 163.611 192.039 1.00 103.84 ? 81  ASN N O   1 
ATOM   3605 C CB  . ASN D 4 81  ? 211.698 162.340 192.740 1.00 103.84 ? 81  ASN N CB  1 
ATOM   3606 C CG  . ASN D 4 81  ? 213.006 161.824 193.291 1.00 103.84 ? 81  ASN N CG  1 
ATOM   3607 O OD1 . ASN D 4 81  ? 213.022 161.032 194.231 1.00 103.84 ? 81  ASN N OD1 1 
ATOM   3608 N ND2 . ASN D 4 81  ? 214.114 162.263 192.706 1.00 103.84 ? 81  ASN N ND2 1 
ATOM   3609 N N   . PRO D 4 82  ? 208.813 164.206 194.118 1.00 102.48 ? 82  PRO N N   1 
ATOM   3610 C CA  . PRO D 4 82  ? 207.758 165.100 193.651 1.00 102.48 ? 82  PRO N CA  1 
ATOM   3611 C C   . PRO D 4 82  ? 208.342 166.467 193.315 1.00 102.48 ? 82  PRO N C   1 
ATOM   3612 O O   . PRO D 4 82  ? 209.526 166.734 193.518 1.00 102.48 ? 82  PRO N O   1 
ATOM   3613 C CB  . PRO D 4 82  ? 206.815 165.141 194.855 1.00 102.48 ? 82  PRO N CB  1 
ATOM   3614 C CG  . PRO D 4 82  ? 207.771 164.977 196.077 1.00 102.48 ? 82  PRO N CG  1 
ATOM   3615 C CD  . PRO D 4 82  ? 209.118 164.488 195.530 1.00 102.48 ? 82  PRO N CD  1 
ATOM   3616 N N   . VAL D 4 83  ? 207.498 167.323 192.747 1.00 97.66  ? 83  VAL N N   1 
ATOM   3617 C CA  . VAL D 4 83  ? 207.908 168.689 192.454 1.00 97.66  ? 83  VAL N CA  1 
ATOM   3618 C C   . VAL D 4 83  ? 207.430 169.598 193.575 1.00 97.66  ? 83  VAL N C   1 
ATOM   3619 O O   . VAL D 4 83  ? 206.293 170.083 193.559 1.00 97.66  ? 83  VAL N O   1 
ATOM   3620 C CB  . VAL D 4 83  ? 207.388 169.160 191.090 1.00 97.66  ? 83  VAL N CB  1 
ATOM   3621 C CG1 . VAL D 4 83  ? 207.844 170.577 190.855 1.00 97.66  ? 83  VAL N CG1 1 
ATOM   3622 C CG2 . VAL D 4 83  ? 207.904 168.242 190.000 1.00 97.66  ? 83  VAL N CG2 1 
ATOM   3623 N N   . LEU D 4 84  ? 208.293 169.815 194.553 1.00 93.92  ? 84  LEU N N   1 
ATOM   3624 C CA  . LEU D 4 84  ? 207.928 170.598 195.719 1.00 93.92  ? 84  LEU N CA  1 
ATOM   3625 C C   . LEU D 4 84  ? 208.065 172.088 195.412 1.00 93.92  ? 84  LEU N C   1 
ATOM   3626 O O   . LEU D 4 84  ? 208.890 172.477 194.580 1.00 93.92  ? 84  LEU N O   1 
ATOM   3627 C CB  . LEU D 4 84  ? 208.832 170.215 196.888 1.00 93.92  ? 84  LEU N CB  1 
ATOM   3628 C CG  . LEU D 4 84  ? 208.695 168.790 197.416 1.00 93.92  ? 84  LEU N CG  1 
ATOM   3629 C CD1 . LEU D 4 84  ? 209.760 168.546 198.459 1.00 93.92  ? 84  LEU N CD1 1 
ATOM   3630 C CD2 . LEU D 4 84  ? 207.312 168.552 197.998 1.00 93.92  ? 84  LEU N CD2 1 
ATOM   3631 N N   . PRO D 4 85  ? 207.272 172.942 196.050 1.00 89.17  ? 85  PRO N N   1 
ATOM   3632 C CA  . PRO D 4 85  ? 207.452 174.389 195.886 1.00 89.17  ? 85  PRO N CA  1 
ATOM   3633 C C   . PRO D 4 85  ? 208.738 174.863 196.546 1.00 89.17  ? 85  PRO N C   1 
ATOM   3634 O O   . PRO D 4 85  ? 209.309 174.206 197.420 1.00 89.17  ? 85  PRO N O   1 
ATOM   3635 C CB  . PRO D 4 85  ? 206.222 174.985 196.577 1.00 89.17  ? 85  PRO N CB  1 
ATOM   3636 C CG  . PRO D 4 85  ? 205.233 173.860 196.639 1.00 89.17  ? 85  PRO N CG  1 
ATOM   3637 C CD  . PRO D 4 85  ? 206.054 172.624 196.810 1.00 89.17  ? 85  PRO N CD  1 
ATOM   3638 N N   . PHE D 4 86  ? 209.194 176.037 196.114 1.00 83.99  ? 86  PHE N N   1 
ATOM   3639 C CA  . PHE D 4 86  ? 210.395 176.647 196.670 1.00 83.99  ? 86  PHE N CA  1 
ATOM   3640 C C   . PHE D 4 86  ? 210.103 177.621 197.801 1.00 83.99  ? 86  PHE N C   1 
ATOM   3641 O O   . PHE D 4 86  ? 210.937 177.769 198.700 1.00 83.99  ? 86  PHE N O   1 
ATOM   3642 C CB  . PHE D 4 86  ? 211.177 177.382 195.578 1.00 83.99  ? 86  PHE N CB  1 
ATOM   3643 C CG  . PHE D 4 86  ? 212.539 177.844 196.009 1.00 83.99  ? 86  PHE N CG  1 
ATOM   3644 C CD1 . PHE D 4 86  ? 212.949 179.147 195.786 1.00 83.99  ? 86  PHE N CD1 1 
ATOM   3645 C CD2 . PHE D 4 86  ? 213.419 176.967 196.620 1.00 83.99  ? 86  PHE N CD2 1 
ATOM   3646 C CE1 . PHE D 4 86  ? 214.204 179.570 196.177 1.00 83.99  ? 86  PHE N CE1 1 
ATOM   3647 C CE2 . PHE D 4 86  ? 214.675 177.385 197.014 1.00 83.99  ? 86  PHE N CE2 1 
ATOM   3648 C CZ  . PHE D 4 86  ? 215.068 178.687 196.791 1.00 83.99  ? 86  PHE N CZ  1 
ATOM   3649 N N   . ASN D 4 87  ? 208.942 178.278 197.775 1.00 81.58  ? 87  ASN N N   1 
ATOM   3650 C CA  . ASN D 4 87  ? 208.555 179.288 198.768 1.00 81.58  ? 87  ASN N CA  1 
ATOM   3651 C C   . ASN D 4 87  ? 209.616 180.380 198.748 1.00 81.58  ? 87  ASN N C   1 
ATOM   3652 O O   . ASN D 4 87  ? 209.794 181.017 197.697 1.00 81.58  ? 87  ASN N O   1 
ATOM   3653 C CB  . ASN D 4 87  ? 208.320 178.604 200.118 1.00 81.58  ? 87  ASN N CB  1 
ATOM   3654 C CG  . ASN D 4 87  ? 206.863 178.262 200.350 1.00 81.58  ? 87  ASN N CG  1 
ATOM   3655 O OD1 . ASN D 4 87  ? 205.970 179.047 200.030 1.00 81.58  ? 87  ASN N OD1 1 
ATOM   3656 N ND2 . ASN D 4 87  ? 206.611 177.085 200.903 1.00 81.58  ? 87  ASN N ND2 1 
ATOM   3657 N N   . ASP D 4 88  ? 210.331 180.635 199.846 1.00 73.36  ? 88  ASP N N   1 
ATOM   3658 C CA  . ASP D 4 88  ? 211.436 181.582 199.851 1.00 73.36  ? 88  ASP N CA  1 
ATOM   3659 C C   . ASP D 4 88  ? 212.793 180.920 200.019 1.00 73.36  ? 88  ASP N C   1 
ATOM   3660 O O   . ASP D 4 88  ? 213.813 181.554 199.726 1.00 73.36  ? 88  ASP N O   1 
ATOM   3661 C CB  . ASP D 4 88  ? 211.248 182.618 200.967 1.00 73.36  ? 88  ASP N CB  1 
ATOM   3662 C CG  . ASP D 4 88  ? 210.409 183.797 200.528 1.00 73.36  ? 88  ASP N CG  1 
ATOM   3663 O OD1 . ASP D 4 88  ? 210.157 183.928 199.313 1.00 73.36  ? 88  ASP N OD1 1 
ATOM   3664 O OD2 . ASP D 4 88  ? 210.004 184.595 201.398 1.00 73.36  ? 88  ASP N OD2 1 
ATOM   3665 N N   . GLY D 4 89  ? 212.829 179.679 200.481 1.00 73.05  ? 89  GLY N N   1 
ATOM   3666 C CA  . GLY D 4 89  ? 214.068 178.940 200.629 1.00 73.05  ? 89  GLY N CA  1 
ATOM   3667 C C   . GLY D 4 89  ? 213.745 177.544 201.105 1.00 73.05  ? 89  GLY N C   1 
ATOM   3668 O O   . GLY D 4 89  ? 212.652 177.276 201.611 1.00 73.05  ? 89  GLY N O   1 
ATOM   3669 N N   . VAL D 4 90  ? 214.709 176.648 200.932 1.00 72.39  ? 90  VAL N N   1 
ATOM   3670 C CA  . VAL D 4 90  ? 214.508 175.254 201.310 1.00 72.39  ? 90  VAL N CA  1 
ATOM   3671 C C   . VAL D 4 90  ? 215.720 174.768 202.087 1.00 72.39  ? 90  VAL N C   1 
ATOM   3672 O O   . VAL D 4 90  ? 216.850 175.200 201.847 1.00 72.39  ? 90  VAL N O   1 
ATOM   3673 C CB  . VAL D 4 90  ? 214.243 174.354 200.081 1.00 72.39  ? 90  VAL N CB  1 
ATOM   3674 C CG1 . VAL D 4 90  ? 212.965 174.774 199.373 1.00 72.39  ? 90  VAL N CG1 1 
ATOM   3675 C CG2 . VAL D 4 90  ? 215.423 174.390 199.126 1.00 72.39  ? 90  VAL N CG2 1 
ATOM   3676 N N   . TYR D 4 91  ? 215.468 173.876 203.038 1.00 77.34  ? 91  TYR N N   1 
ATOM   3677 C CA  . TYR D 4 91  ? 216.510 173.104 203.692 1.00 77.34  ? 91  TYR N CA  1 
ATOM   3678 C C   . TYR D 4 91  ? 216.488 171.691 203.130 1.00 77.34  ? 91  TYR N C   1 
ATOM   3679 O O   . TYR D 4 91  ? 215.448 171.026 203.154 1.00 77.34  ? 91  TYR N O   1 
ATOM   3680 C CB  . TYR D 4 91  ? 216.314 173.072 205.207 1.00 77.34  ? 91  TYR N CB  1 
ATOM   3681 C CG  . TYR D 4 91  ? 217.261 172.126 205.901 1.00 77.34  ? 91  TYR N CG  1 
ATOM   3682 C CD1 . TYR D 4 91  ? 218.613 172.412 205.993 1.00 77.34  ? 91  TYR N CD1 1 
ATOM   3683 C CD2 . TYR D 4 91  ? 216.805 170.934 206.446 1.00 77.34  ? 91  TYR N CD2 1 
ATOM   3684 C CE1 . TYR D 4 91  ? 219.485 171.548 206.617 1.00 77.34  ? 91  TYR N CE1 1 
ATOM   3685 C CE2 . TYR D 4 91  ? 217.671 170.059 207.073 1.00 77.34  ? 91  TYR N CE2 1 
ATOM   3686 C CZ  . TYR D 4 91  ? 219.008 170.374 207.156 1.00 77.34  ? 91  TYR N CZ  1 
ATOM   3687 O OH  . TYR D 4 91  ? 219.877 169.509 207.774 1.00 77.34  ? 91  TYR N OH  1 
ATOM   3688 N N   . PHE D 4 92  ? 217.630 171.234 202.625 1.00 84.33  ? 92  PHE N N   1 
ATOM   3689 C CA  . PHE D 4 92  ? 217.741 169.916 202.024 1.00 84.33  ? 92  PHE N CA  1 
ATOM   3690 C C   . PHE D 4 92  ? 218.766 169.111 202.804 1.00 84.33  ? 92  PHE N C   1 
ATOM   3691 O O   . PHE D 4 92  ? 219.820 169.638 203.171 1.00 84.33  ? 92  PHE N O   1 
ATOM   3692 C CB  . PHE D 4 92  ? 218.135 170.014 200.546 1.00 84.33  ? 92  PHE N CB  1 
ATOM   3693 C CG  . PHE D 4 92  ? 218.275 168.684 199.859 1.00 84.33  ? 92  PHE N CG  1 
ATOM   3694 C CD1 . PHE D 4 92  ? 219.462 167.968 199.928 1.00 84.33  ? 92  PHE N CD1 1 
ATOM   3695 C CD2 . PHE D 4 92  ? 217.221 168.150 199.140 1.00 84.33  ? 92  PHE N CD2 1 
ATOM   3696 C CE1 . PHE D 4 92  ? 219.590 166.747 199.299 1.00 84.33  ? 92  PHE N CE1 1 
ATOM   3697 C CE2 . PHE D 4 92  ? 217.344 166.928 198.510 1.00 84.33  ? 92  PHE N CE2 1 
ATOM   3698 C CZ  . PHE D 4 92  ? 218.531 166.227 198.590 1.00 84.33  ? 92  PHE N CZ  1 
ATOM   3699 N N   . ALA D 4 93  ? 218.453 167.843 203.062 1.00 90.86  ? 93  ALA N N   1 
ATOM   3700 C CA  . ALA D 4 93  ? 219.377 166.950 203.744 1.00 90.86  ? 93  ALA N CA  1 
ATOM   3701 C C   . ALA D 4 93  ? 219.078 165.519 203.327 1.00 90.86  ? 93  ALA N C   1 
ATOM   3702 O O   . ALA D 4 93  ? 217.927 165.165 203.056 1.00 90.86  ? 93  ALA N O   1 
ATOM   3703 C CB  . ALA D 4 93  ? 219.287 167.094 205.266 1.00 90.86  ? 93  ALA N CB  1 
ATOM   3704 N N   . SER D 4 94  ? 220.125 164.702 203.274 1.00 98.61  ? 94  SER N N   1 
ATOM   3705 C CA  . SER D 4 94  ? 219.980 163.302 202.902 1.00 98.61  ? 94  SER N CA  1 
ATOM   3706 C C   . SER D 4 94  ? 221.161 162.517 203.450 1.00 98.61  ? 94  SER N C   1 
ATOM   3707 O O   . SER D 4 94  ? 222.266 163.055 203.565 1.00 98.61  ? 94  SER N O   1 
ATOM   3708 C CB  . SER D 4 94  ? 219.886 163.136 201.382 1.00 98.61  ? 94  SER N CB  1 
ATOM   3709 O OG  . SER D 4 94  ? 219.494 161.820 201.036 1.00 98.61  ? 94  SER N OG  1 
ATOM   3710 N N   . THR D 4 95  ? 220.920 161.255 203.783 1.00 102.49 ? 95  THR N N   1 
ATOM   3711 C CA  . THR D 4 95  ? 221.973 160.387 204.299 1.00 102.49 ? 95  THR N CA  1 
ATOM   3712 C C   . THR D 4 95  ? 222.322 159.301 203.289 1.00 102.49 ? 95  THR N C   1 
ATOM   3713 O O   . THR D 4 95  ? 223.261 158.527 203.492 1.00 102.49 ? 95  THR N O   1 
ATOM   3714 C CB  . THR D 4 95  ? 221.566 159.730 205.630 1.00 102.49 ? 95  THR N CB  1 
ATOM   3715 O OG1 . THR D 4 95  ? 222.710 159.116 206.234 1.00 102.49 ? 95  THR N OG1 1 
ATOM   3716 C CG2 . THR D 4 95  ? 220.495 158.675 205.397 1.00 102.49 ? 95  THR N CG2 1 
ATOM   3717 N N   . ARG D 4 102 ? 221.384 163.072 193.167 1.00 112.24 ? 102 ARG N N   1 
ATOM   3718 C CA  . ARG D 4 102 ? 222.704 163.690 193.128 1.00 112.24 ? 102 ARG N CA  1 
ATOM   3719 C C   . ARG D 4 102 ? 222.663 165.031 192.408 1.00 112.24 ? 102 ARG N C   1 
ATOM   3720 O O   . ARG D 4 102 ? 223.643 165.443 191.790 1.00 112.24 ? 102 ARG N O   1 
ATOM   3721 C CB  . ARG D 4 102 ? 223.713 162.760 192.450 1.00 112.24 ? 102 ARG N CB  1 
ATOM   3722 C CG  . ARG D 4 102 ? 223.906 161.424 193.150 1.00 112.24 ? 102 ARG N CG  1 
ATOM   3723 C CD  . ARG D 4 102 ? 224.626 161.590 194.478 1.00 112.24 ? 102 ARG N CD  1 
ATOM   3724 N NE  . ARG D 4 102 ? 224.882 160.308 195.124 1.00 112.24 ? 102 ARG N NE  1 
ATOM   3725 C CZ  . ARG D 4 102 ? 224.058 159.727 195.985 1.00 112.24 ? 102 ARG N CZ  1 
ATOM   3726 N NH1 . ARG D 4 102 ? 222.910 160.287 196.329 1.00 112.24 ? 102 ARG N NH1 1 
ATOM   3727 N NH2 . ARG D 4 102 ? 224.395 158.553 196.514 1.00 112.24 ? 102 ARG N NH2 1 
ATOM   3728 N N   . GLY D 4 103 ? 221.524 165.708 192.488 1.00 101.24 ? 103 GLY N N   1 
ATOM   3729 C CA  . GLY D 4 103 ? 221.389 166.994 191.834 1.00 101.24 ? 103 GLY N CA  1 
ATOM   3730 C C   . GLY D 4 103 ? 220.038 167.607 192.117 1.00 101.24 ? 103 GLY N C   1 
ATOM   3731 O O   . GLY D 4 103 ? 219.205 167.029 192.822 1.00 101.24 ? 103 GLY N O   1 
ATOM   3732 N N   . TRP D 4 104 ? 219.828 168.794 191.553 1.00 93.55  ? 104 TRP N N   1 
ATOM   3733 C CA  . TRP D 4 104 ? 218.582 169.524 191.743 1.00 93.55  ? 104 TRP N CA  1 
ATOM   3734 C C   . TRP D 4 104 ? 218.229 170.245 190.452 1.00 93.55  ? 104 TRP N C   1 
ATOM   3735 O O   . TRP D 4 104 ? 219.109 170.611 189.669 1.00 93.55  ? 104 TRP N O   1 
ATOM   3736 C CB  . TRP D 4 104 ? 218.687 170.528 192.898 1.00 93.55  ? 104 TRP N CB  1 
ATOM   3737 C CG  . TRP D 4 104 ? 219.009 169.901 194.216 1.00 93.55  ? 104 TRP N CG  1 
ATOM   3738 C CD1 . TRP D 4 104 ? 218.124 169.416 195.132 1.00 93.55  ? 104 TRP N CD1 1 
ATOM   3739 C CD2 . TRP D 4 104 ? 220.314 169.677 194.761 1.00 93.55  ? 104 TRP N CD2 1 
ATOM   3740 N NE1 . TRP D 4 104 ? 218.797 168.910 196.217 1.00 93.55  ? 104 TRP N NE1 1 
ATOM   3741 C CE2 . TRP D 4 104 ? 220.144 169.057 196.013 1.00 93.55  ? 104 TRP N CE2 1 
ATOM   3742 C CE3 . TRP D 4 104 ? 221.611 169.943 194.312 1.00 93.55  ? 104 TRP N CE3 1 
ATOM   3743 C CZ2 . TRP D 4 104 ? 221.219 168.697 196.821 1.00 93.55  ? 104 TRP N CZ2 1 
ATOM   3744 C CZ3 . TRP D 4 104 ? 222.676 169.586 195.115 1.00 93.55  ? 104 TRP N CZ3 1 
ATOM   3745 C CH2 . TRP D 4 104 ? 222.476 168.971 196.355 1.00 93.55  ? 104 TRP N CH2 1 
ATOM   3746 N N   . ILE D 4 105 ? 216.931 170.442 190.242 1.00 94.92  ? 105 ILE N N   1 
ATOM   3747 C CA  . ILE D 4 105 ? 216.412 171.225 189.129 1.00 94.92  ? 105 ILE N CA  1 
ATOM   3748 C C   . ILE D 4 105 ? 215.446 172.252 189.689 1.00 94.92  ? 105 ILE N C   1 
ATOM   3749 O O   . ILE D 4 105 ? 214.465 171.895 190.349 1.00 94.92  ? 105 ILE N O   1 
ATOM   3750 C CB  . ILE D 4 105 ? 215.705 170.343 188.075 1.00 94.92  ? 105 ILE N CB  1 
ATOM   3751 C CG1 . ILE D 4 105 ? 216.680 169.333 187.469 1.00 94.92  ? 105 ILE N CG1 1 
ATOM   3752 C CG2 . ILE D 4 105 ? 215.073 171.209 186.996 1.00 94.92  ? 105 ILE N CG2 1 
ATOM   3753 C CD1 . ILE D 4 105 ? 216.527 167.937 188.027 1.00 94.92  ? 105 ILE N CD1 1 
ATOM   3754 N N   . PHE D 4 106 ? 215.715 173.528 189.428 1.00 96.80  ? 106 PHE N N   1 
ATOM   3755 C CA  . PHE D 4 106 ? 214.888 174.600 189.956 1.00 96.80  ? 106 PHE N CA  1 
ATOM   3756 C C   . PHE D 4 106 ? 214.258 175.352 188.792 1.00 96.80  ? 106 PHE N C   1 
ATOM   3757 O O   . PHE D 4 106 ? 214.722 175.262 187.652 1.00 96.80  ? 106 PHE N O   1 
ATOM   3758 C CB  . PHE D 4 106 ? 215.696 175.571 190.827 1.00 96.80  ? 106 PHE N CB  1 
ATOM   3759 C CG  . PHE D 4 106 ? 216.199 174.975 192.111 1.00 96.80  ? 106 PHE N CG  1 
ATOM   3760 C CD1 . PHE D 4 106 ? 215.707 173.778 192.575 1.00 96.80  ? 106 PHE N CD1 1 
ATOM   3761 C CD2 . PHE D 4 106 ? 217.119 175.650 192.887 1.00 96.80  ? 106 PHE N CD2 1 
ATOM   3762 C CE1 . PHE D 4 106 ? 216.162 173.230 193.759 1.00 96.80  ? 106 PHE N CE1 1 
ATOM   3763 C CE2 . PHE D 4 106 ? 217.561 175.109 194.078 1.00 96.80  ? 106 PHE N CE2 1 
ATOM   3764 C CZ  . PHE D 4 106 ? 217.085 173.903 194.512 1.00 96.80  ? 106 PHE N CZ  1 
ATOM   3765 N N   . GLY D 4 107 ? 213.197 176.092 189.078 1.00 102.32 ? 107 GLY N N   1 
ATOM   3766 C CA  . GLY D 4 107 ? 212.560 176.897 188.055 1.00 102.32 ? 107 GLY N CA  1 
ATOM   3767 C C   . GLY D 4 107 ? 211.149 177.285 188.451 1.00 102.32 ? 107 GLY N C   1 
ATOM   3768 O O   . GLY D 4 107 ? 210.692 177.009 189.560 1.00 102.32 ? 107 GLY N O   1 
ATOM   3769 N N   . THR D 4 108 ? 210.471 177.942 187.507 1.00 111.27 ? 108 THR N N   1 
ATOM   3770 C CA  . THR D 4 108 ? 209.085 178.365 187.700 1.00 111.27 ? 108 THR N CA  1 
ATOM   3771 C C   . THR D 4 108 ? 208.118 177.404 187.024 1.00 111.27 ? 108 THR N C   1 
ATOM   3772 O O   . THR D 4 108 ? 207.220 176.861 187.671 1.00 111.27 ? 108 THR N O   1 
ATOM   3773 C CB  . THR D 4 108 ? 208.862 179.775 187.151 1.00 111.27 ? 108 THR N CB  1 
ATOM   3774 O OG1 . THR D 4 108 ? 209.180 179.805 185.756 1.00 111.27 ? 108 THR N OG1 1 
ATOM   3775 C CG2 . THR D 4 108 ? 209.724 180.779 187.887 1.00 111.27 ? 108 THR N CG2 1 
ATOM   3776 N N   . THR D 4 109 ? 208.281 177.202 185.717 1.00 121.55 ? 109 THR N N   1 
ATOM   3777 C CA  . THR D 4 109 ? 207.430 176.294 184.964 1.00 121.55 ? 109 THR N CA  1 
ATOM   3778 C C   . THR D 4 109 ? 208.153 175.028 184.527 1.00 121.55 ? 109 THR N C   1 
ATOM   3779 O O   . THR D 4 109 ? 207.489 174.072 184.109 1.00 121.55 ? 109 THR N O   1 
ATOM   3780 C CB  . THR D 4 109 ? 206.854 176.996 183.729 1.00 121.55 ? 109 THR N CB  1 
ATOM   3781 O OG1 . THR D 4 109 ? 207.925 177.428 182.880 1.00 121.55 ? 109 THR N OG1 1 
ATOM   3782 C CG2 . THR D 4 109 ? 206.024 178.201 184.140 1.00 121.55 ? 109 THR N CG2 1 
ATOM   3783 N N   . LEU D 4 110 ? 209.485 175.003 184.614 1.00 124.11 ? 110 LEU N N   1 
ATOM   3784 C CA  . LEU D 4 110 ? 210.286 173.840 184.230 1.00 124.11 ? 110 LEU N CA  1 
ATOM   3785 C C   . LEU D 4 110 ? 210.019 173.438 182.781 1.00 124.11 ? 110 LEU N C   1 
ATOM   3786 O O   . LEU D 4 110 ? 210.006 172.256 182.435 1.00 124.11 ? 110 LEU N O   1 
ATOM   3787 C CB  . LEU D 4 110 ? 210.040 172.668 185.182 1.00 124.11 ? 110 LEU N CB  1 
ATOM   3788 C CG  . LEU D 4 110 ? 210.250 172.974 186.666 1.00 124.11 ? 110 LEU N CG  1 
ATOM   3789 C CD1 . LEU D 4 110 ? 209.785 171.813 187.527 1.00 124.11 ? 110 LEU N CD1 1 
ATOM   3790 C CD2 . LEU D 4 110 ? 211.708 173.308 186.948 1.00 124.11 ? 110 LEU N CD2 1 
ATOM   3791 N N   . ASP D 4 111 ? 209.804 174.435 181.932 1.00 139.83 ? 111 ASP N N   1 
ATOM   3792 C CA  . ASP D 4 111 ? 209.505 174.250 180.520 1.00 139.83 ? 111 ASP N CA  1 
ATOM   3793 C C   . ASP D 4 111 ? 210.434 175.157 179.708 1.00 139.83 ? 111 ASP N C   1 
ATOM   3794 O O   . ASP D 4 111 ? 211.271 175.872 180.263 1.00 139.83 ? 111 ASP N O   1 
ATOM   3795 C CB  . ASP D 4 111 ? 208.022 174.537 180.260 1.00 139.83 ? 111 ASP N CB  1 
ATOM   3796 C CG  . ASP D 4 111 ? 207.578 174.144 178.864 1.00 139.83 ? 111 ASP N CG  1 
ATOM   3797 O OD1 . ASP D 4 111 ? 207.293 172.950 178.644 1.00 139.83 ? 111 ASP N OD1 1 
ATOM   3798 O OD2 . ASP D 4 111 ? 207.522 175.029 177.986 1.00 139.83 ? 111 ASP N OD2 1 
ATOM   3799 N N   . SER D 4 112 ? 210.292 175.121 178.385 1.00 144.27 ? 112 SER N N   1 
ATOM   3800 C CA  . SER D 4 112 ? 211.058 176.014 177.526 1.00 144.27 ? 112 SER N CA  1 
ATOM   3801 C C   . SER D 4 112 ? 210.542 177.446 177.552 1.00 144.27 ? 112 SER N C   1 
ATOM   3802 O O   . SER D 4 112 ? 211.219 178.341 177.034 1.00 144.27 ? 112 SER N O   1 
ATOM   3803 C CB  . SER D 4 112 ? 211.058 175.496 176.085 1.00 144.27 ? 112 SER N CB  1 
ATOM   3804 O OG  . SER D 4 112 ? 209.756 175.103 175.686 1.00 144.27 ? 112 SER N OG  1 
ATOM   3805 N N   . LYS D 4 113 ? 209.361 177.684 178.132 1.00 140.51 ? 113 LYS N N   1 
ATOM   3806 C CA  . LYS D 4 113 ? 208.844 179.044 178.235 1.00 140.51 ? 113 LYS N CA  1 
ATOM   3807 C C   . LYS D 4 113 ? 209.704 179.903 179.151 1.00 140.51 ? 113 LYS N C   1 
ATOM   3808 O O   . LYS D 4 113 ? 209.851 181.107 178.912 1.00 140.51 ? 113 LYS N O   1 
ATOM   3809 C CB  . LYS D 4 113 ? 207.401 179.020 178.738 1.00 140.51 ? 113 LYS N CB  1 
ATOM   3810 C CG  . LYS D 4 113 ? 206.477 178.099 177.966 1.00 140.51 ? 113 LYS N CG  1 
ATOM   3811 C CD  . LYS D 4 113 ? 206.455 178.433 176.486 1.00 140.51 ? 113 LYS N CD  1 
ATOM   3812 C CE  . LYS D 4 113 ? 205.193 177.905 175.821 1.00 140.51 ? 113 LYS N CE  1 
ATOM   3813 N NZ  . LYS D 4 113 ? 205.234 178.057 174.341 1.00 140.51 ? 113 LYS N NZ  1 
ATOM   3814 N N   . THR D 4 114 ? 210.274 179.310 180.200 1.00 137.08 ? 114 THR N N   1 
ATOM   3815 C CA  . THR D 4 114 ? 211.048 180.035 181.194 1.00 137.08 ? 114 THR N CA  1 
ATOM   3816 C C   . THR D 4 114 ? 212.385 179.338 181.414 1.00 137.08 ? 114 THR N C   1 
ATOM   3817 O O   . THR D 4 114 ? 212.548 178.152 181.118 1.00 137.08 ? 114 THR N O   1 
ATOM   3818 C CB  . THR D 4 114 ? 210.299 180.139 182.530 1.00 137.08 ? 114 THR N CB  1 
ATOM   3819 O OG1 . THR D 4 114 ? 210.024 178.827 183.032 1.00 137.08 ? 114 THR N OG1 1 
ATOM   3820 C CG2 . THR D 4 114 ? 208.989 180.894 182.354 1.00 137.08 ? 114 THR N CG2 1 
ATOM   3821 N N   . GLN D 4 115 ? 213.345 180.095 181.937 1.00 131.22 ? 115 GLN N N   1 
ATOM   3822 C CA  . GLN D 4 115 ? 214.650 179.542 182.261 1.00 131.22 ? 115 GLN N CA  1 
ATOM   3823 C C   . GLN D 4 115 ? 214.591 178.761 183.570 1.00 131.22 ? 115 GLN N C   1 
ATOM   3824 O O   . GLN D 4 115 ? 213.857 179.109 184.497 1.00 131.22 ? 115 GLN N O   1 
ATOM   3825 C CB  . GLN D 4 115 ? 215.696 180.651 182.361 1.00 131.22 ? 115 GLN N CB  1 
ATOM   3826 C CG  . GLN D 4 115 ? 216.097 181.237 181.021 1.00 131.22 ? 115 GLN N CG  1 
ATOM   3827 C CD  . GLN D 4 115 ? 217.491 181.830 181.046 1.00 131.22 ? 115 GLN N CD  1 
ATOM   3828 O OE1 . GLN D 4 115 ? 217.773 182.748 181.815 1.00 131.22 ? 115 GLN N OE1 1 
ATOM   3829 N NE2 . GLN D 4 115 ? 218.371 181.304 180.204 1.00 131.22 ? 115 GLN N NE2 1 
ATOM   3830 N N   . SER D 4 116 ? 215.385 177.693 183.638 1.00 121.25 ? 116 SER N N   1 
ATOM   3831 C CA  . SER D 4 116 ? 215.396 176.806 184.789 1.00 121.25 ? 116 SER N CA  1 
ATOM   3832 C C   . SER D 4 116 ? 216.830 176.483 185.184 1.00 121.25 ? 116 SER N C   1 
ATOM   3833 O O   . SER D 4 116 ? 217.702 176.285 184.336 1.00 121.25 ? 116 SER N O   1 
ATOM   3834 C CB  . SER D 4 116 ? 214.627 175.508 184.499 1.00 121.25 ? 116 SER N CB  1 
ATOM   3835 O OG  . SER D 4 116 ? 213.377 175.785 183.895 1.00 121.25 ? 116 SER N OG  1 
ATOM   3836 N N   . LEU D 4 117 ? 217.058 176.411 186.492 1.00 105.44 ? 117 LEU N N   1 
ATOM   3837 C CA  . LEU D 4 117 ? 218.362 176.097 187.051 1.00 105.44 ? 117 LEU N CA  1 
ATOM   3838 C C   . LEU D 4 117 ? 218.542 174.588 187.143 1.00 105.44 ? 117 LEU N C   1 
ATOM   3839 O O   . LEU D 4 117 ? 217.606 173.852 187.466 1.00 105.44 ? 117 LEU N O   1 
ATOM   3840 C CB  . LEU D 4 117 ? 218.531 176.727 188.435 1.00 105.44 ? 117 LEU N CB  1 
ATOM   3841 C CG  . LEU D 4 117 ? 219.884 176.534 189.118 1.00 105.44 ? 117 LEU N CG  1 
ATOM   3842 C CD1 . LEU D 4 117 ? 220.980 177.186 188.301 1.00 105.44 ? 117 LEU N CD1 1 
ATOM   3843 C CD2 . LEU D 4 117 ? 219.863 177.085 190.532 1.00 105.44 ? 117 LEU N CD2 1 
ATOM   3844 N N   . LEU D 4 118 ? 219.759 174.130 186.855 1.00 109.86 ? 118 LEU N N   1 
ATOM   3845 C CA  . LEU D 4 118 ? 220.053 172.701 186.841 1.00 109.86 ? 118 LEU N CA  1 
ATOM   3846 C C   . LEU D 4 118 ? 221.422 172.477 187.462 1.00 109.86 ? 118 LEU N C   1 
ATOM   3847 O O   . LEU D 4 118 ? 222.412 173.062 187.012 1.00 109.86 ? 118 LEU N O   1 
ATOM   3848 C CB  . LEU D 4 118 ? 220.000 172.154 185.411 1.00 109.86 ? 118 LEU N CB  1 
ATOM   3849 C CG  . LEU D 4 118 ? 220.107 170.645 185.168 1.00 109.86 ? 118 LEU N CG  1 
ATOM   3850 C CD1 . LEU D 4 118 ? 219.399 170.288 183.874 1.00 109.86 ? 118 LEU N CD1 1 
ATOM   3851 C CD2 . LEU D 4 118 ? 221.556 170.194 185.099 1.00 109.86 ? 118 LEU N CD2 1 
ATOM   3852 N N   . ILE D 4 119 ? 221.477 171.631 188.489 1.00 104.97 ? 119 ILE N N   1 
ATOM   3853 C CA  . ILE D 4 119 ? 222.717 171.276 189.167 1.00 104.97 ? 119 ILE N CA  1 
ATOM   3854 C C   . ILE D 4 119 ? 222.884 169.765 189.098 1.00 104.97 ? 119 ILE N C   1 
ATOM   3855 O O   . ILE D 4 119 ? 221.961 169.016 189.439 1.00 104.97 ? 119 ILE N O   1 
ATOM   3856 C CB  . ILE D 4 119 ? 222.721 171.762 190.626 1.00 104.97 ? 119 ILE N CB  1 
ATOM   3857 C CG1 . ILE D 4 119 ? 222.547 173.279 190.686 1.00 104.97 ? 119 ILE N CG1 1 
ATOM   3858 C CG2 . ILE D 4 119 ? 224.006 171.341 191.325 1.00 104.97 ? 119 ILE N CG2 1 
ATOM   3859 C CD1 . ILE D 4 119 ? 222.365 173.817 192.085 1.00 104.97 ? 119 ILE N CD1 1 
ATOM   3860 N N   . VAL D 4 120 ? 224.056 169.317 188.651 1.00 116.94 ? 120 VAL N N   1 
ATOM   3861 C CA  . VAL D 4 120 ? 224.380 167.896 188.577 1.00 116.94 ? 120 VAL N CA  1 
ATOM   3862 C C   . VAL D 4 120 ? 225.765 167.684 189.166 1.00 116.94 ? 120 VAL N C   1 
ATOM   3863 O O   . VAL D 4 120 ? 226.673 168.492 188.938 1.00 116.94 ? 120 VAL N O   1 
ATOM   3864 C CB  . VAL D 4 120 ? 224.319 167.360 187.133 1.00 116.94 ? 120 VAL N CB  1 
ATOM   3865 C CG1 . VAL D 4 120 ? 222.881 167.236 186.677 1.00 116.94 ? 120 VAL N CG1 1 
ATOM   3866 C CG2 . VAL D 4 120 ? 225.094 168.266 186.196 1.00 116.94 ? 120 VAL N CG2 1 
ATOM   3867 N N   . ASN D 4 121 ? 225.933 166.602 189.919 1.00 125.61 ? 121 ASN N N   1 
ATOM   3868 C CA  . ASN D 4 121 ? 227.201 166.267 190.559 1.00 125.61 ? 121 ASN N CA  1 
ATOM   3869 C C   . ASN D 4 121 ? 227.748 164.994 189.926 1.00 125.61 ? 121 ASN N C   1 
ATOM   3870 O O   . ASN D 4 121 ? 227.153 163.920 190.062 1.00 125.61 ? 121 ASN N O   1 
ATOM   3871 C CB  . ASN D 4 121 ? 227.023 166.092 192.065 1.00 125.61 ? 121 ASN N CB  1 
ATOM   3872 C CG  . ASN D 4 121 ? 226.898 167.414 192.793 1.00 125.61 ? 121 ASN N CG  1 
ATOM   3873 O OD1 . ASN D 4 121 ? 227.868 167.916 193.362 1.00 125.61 ? 121 ASN N OD1 1 
ATOM   3874 N ND2 . ASN D 4 121 ? 225.700 167.986 192.778 1.00 125.61 ? 121 ASN N ND2 1 
ATOM   3875 N N   . ASN D 4 122 ? 228.880 165.116 189.243 1.00 138.23 ? 122 ASN N N   1 
ATOM   3876 C CA  . ASN D 4 122 ? 229.589 163.955 188.724 1.00 138.23 ? 122 ASN N CA  1 
ATOM   3877 C C   . ASN D 4 122 ? 230.423 163.351 189.853 1.00 138.23 ? 122 ASN N C   1 
ATOM   3878 O O   . ASN D 4 122 ? 230.397 163.806 190.998 1.00 138.23 ? 122 ASN N O   1 
ATOM   3879 C CB  . ASN D 4 122 ? 230.451 164.348 187.528 1.00 138.23 ? 122 ASN N CB  1 
ATOM   3880 C CG  . ASN D 4 122 ? 229.752 164.121 186.205 1.00 138.23 ? 122 ASN N CG  1 
ATOM   3881 O OD1 . ASN D 4 122 ? 228.681 163.520 186.150 1.00 138.23 ? 122 ASN N OD1 1 
ATOM   3882 N ND2 . ASN D 4 122 ? 230.359 164.606 185.126 1.00 138.23 ? 122 ASN N ND2 1 
ATOM   3883 N N   . ALA D 4 123 ? 231.182 162.303 189.533 1.00 145.33 ? 123 ALA N N   1 
ATOM   3884 C CA  . ALA D 4 123 ? 232.134 161.766 190.495 1.00 145.33 ? 123 ALA N CA  1 
ATOM   3885 C C   . ALA D 4 123 ? 233.359 162.651 190.649 1.00 145.33 ? 123 ALA N C   1 
ATOM   3886 O O   . ALA D 4 123 ? 234.131 162.464 191.596 1.00 145.33 ? 123 ALA N O   1 
ATOM   3887 C CB  . ALA D 4 123 ? 232.564 160.355 190.084 1.00 145.33 ? 123 ALA N CB  1 
ATOM   3888 N N   . THR D 4 124 ? 233.553 163.609 189.742 1.00 141.30 ? 124 THR N N   1 
ATOM   3889 C CA  . THR D 4 124 ? 234.730 164.466 189.737 1.00 141.30 ? 124 THR N CA  1 
ATOM   3890 C C   . THR D 4 124 ? 234.417 165.950 189.661 1.00 141.30 ? 124 THR N C   1 
ATOM   3891 O O   . THR D 4 124 ? 235.307 166.765 189.902 1.00 141.30 ? 124 THR N O   1 
ATOM   3892 C CB  . THR D 4 124 ? 235.638 164.113 188.550 1.00 141.30 ? 124 THR N CB  1 
ATOM   3893 O OG1 . THR D 4 124 ? 234.895 164.231 187.329 1.00 141.30 ? 124 THR N OG1 1 
ATOM   3894 C CG2 . THR D 4 124 ? 236.172 162.694 188.676 1.00 141.30 ? 124 THR N CG2 1 
ATOM   3895 N N   . ASN D 4 125 ? 233.185 166.326 189.326 1.00 132.43 ? 125 ASN N N   1 
ATOM   3896 C CA  . ASN D 4 125 ? 232.904 167.683 188.881 1.00 132.43 ? 125 ASN N CA  1 
ATOM   3897 C C   . ASN D 4 125 ? 231.431 167.994 189.106 1.00 132.43 ? 125 ASN N C   1 
ATOM   3898 O O   . ASN D 4 125 ? 230.574 167.113 189.029 1.00 132.43 ? 125 ASN N O   1 
ATOM   3899 C CB  . ASN D 4 125 ? 233.293 167.821 187.400 1.00 132.43 ? 125 ASN N CB  1 
ATOM   3900 C CG  . ASN D 4 125 ? 233.236 169.244 186.892 1.00 132.43 ? 125 ASN N CG  1 
ATOM   3901 O OD1 . ASN D 4 125 ? 232.883 170.169 187.614 1.00 132.43 ? 125 ASN N OD1 1 
ATOM   3902 N ND2 . ASN D 4 125 ? 233.594 169.424 185.628 1.00 132.43 ? 125 ASN N ND2 1 
ATOM   3903 N N   . VAL D 4 126 ? 231.139 169.262 189.380 1.00 124.13 ? 126 VAL N N   1 
ATOM   3904 C CA  . VAL D 4 126 ? 229.760 169.727 189.481 1.00 124.13 ? 126 VAL N CA  1 
ATOM   3905 C C   . VAL D 4 126 ? 229.509 170.708 188.345 1.00 124.13 ? 126 VAL N C   1 
ATOM   3906 O O   . VAL D 4 126 ? 230.371 171.522 187.990 1.00 124.13 ? 126 VAL N O   1 
ATOM   3907 C CB  . VAL D 4 126 ? 229.426 170.362 190.852 1.00 124.13 ? 126 VAL N CB  1 
ATOM   3908 C CG1 . VAL D 4 126 ? 230.079 171.727 191.016 1.00 124.13 ? 126 VAL N CG1 1 
ATOM   3909 C CG2 . VAL D 4 126 ? 227.918 170.467 191.040 1.00 124.13 ? 126 VAL N CG2 1 
ATOM   3910 N N   . VAL D 4 127 ? 228.330 170.593 187.739 1.00 117.85 ? 127 VAL N N   1 
ATOM   3911 C CA  . VAL D 4 127 ? 227.949 171.430 186.608 1.00 117.85 ? 127 VAL N CA  1 
ATOM   3912 C C   . VAL D 4 127 ? 226.661 172.152 186.968 1.00 117.85 ? 127 VAL N C   1 
ATOM   3913 O O   . VAL D 4 127 ? 225.677 171.515 187.355 1.00 117.85 ? 127 VAL N O   1 
ATOM   3914 C CB  . VAL D 4 127 ? 227.755 170.615 185.317 1.00 117.85 ? 127 VAL N CB  1 
ATOM   3915 C CG1 . VAL D 4 127 ? 227.431 171.535 184.155 1.00 117.85 ? 127 VAL N CG1 1 
ATOM   3916 C CG2 . VAL D 4 127 ? 228.992 169.782 185.023 1.00 117.85 ? 127 VAL N CG2 1 
ATOM   3917 N N   . ILE D 4 128 ? 226.664 173.474 186.837 1.00 111.47 ? 128 ILE N N   1 
ATOM   3918 C CA  . ILE D 4 128 ? 225.479 174.288 187.072 1.00 111.47 ? 128 ILE N CA  1 
ATOM   3919 C C   . ILE D 4 128 ? 225.186 175.056 185.793 1.00 111.47 ? 128 ILE N C   1 
ATOM   3920 O O   . ILE D 4 128 ? 226.018 175.851 185.338 1.00 111.47 ? 128 ILE N O   1 
ATOM   3921 C CB  . ILE D 4 128 ? 225.654 175.252 188.252 1.00 111.47 ? 128 ILE N CB  1 
ATOM   3922 C CG1 . ILE D 4 128 ? 225.821 174.482 189.565 1.00 111.47 ? 128 ILE N CG1 1 
ATOM   3923 C CG2 . ILE D 4 128 ? 224.450 176.158 188.338 1.00 111.47 ? 128 ILE N CG2 1 
ATOM   3924 C CD1 . ILE D 4 128 ? 227.263 174.181 189.928 1.00 111.47 ? 128 ILE N CD1 1 
ATOM   3925 N N   . LYS D 4 129 ? 224.012 174.824 185.222 1.00 117.59 ? 129 LYS N N   1 
ATOM   3926 C CA  . LYS D 4 129 ? 223.596 175.464 183.985 1.00 117.59 ? 129 LYS N CA  1 
ATOM   3927 C C   . LYS D 4 129 ? 222.166 175.948 184.144 1.00 117.59 ? 129 LYS N C   1 
ATOM   3928 O O   . LYS D 4 129 ? 221.375 175.337 184.868 1.00 117.59 ? 129 LYS N O   1 
ATOM   3929 C CB  . LYS D 4 129 ? 223.697 174.492 182.807 1.00 117.59 ? 129 LYS N CB  1 
ATOM   3930 C CG  . LYS D 4 129 ? 225.101 173.983 182.539 1.00 117.59 ? 129 LYS N CG  1 
ATOM   3931 C CD  . LYS D 4 129 ? 225.132 173.084 181.318 1.00 117.59 ? 129 LYS N CD  1 
ATOM   3932 C CE  . LYS D 4 129 ? 224.507 171.734 181.631 1.00 117.59 ? 129 LYS N CE  1 
ATOM   3933 N NZ  . LYS D 4 129 ? 224.615 170.783 180.494 1.00 117.59 ? 129 LYS N NZ  1 
ATOM   3934 N N   . VAL D 4 130 ? 221.831 177.044 183.471 1.00 124.24 ? 130 VAL N N   1 
ATOM   3935 C CA  . VAL D 4 130 ? 220.472 177.570 183.478 1.00 124.24 ? 130 VAL N CA  1 
ATOM   3936 C C   . VAL D 4 130 ? 219.997 177.766 182.041 1.00 124.24 ? 130 VAL N C   1 
ATOM   3937 O O   . VAL D 4 130 ? 220.043 178.877 181.499 1.00 124.24 ? 130 VAL N O   1 
ATOM   3938 C CB  . VAL D 4 130 ? 220.374 178.852 184.333 1.00 124.24 ? 130 VAL N CB  1 
ATOM   3939 C CG1 . VAL D 4 130 ? 221.208 180.017 183.773 1.00 124.24 ? 130 VAL N CG1 1 
ATOM   3940 C CG2 . VAL D 4 130 ? 218.924 179.273 184.482 1.00 124.24 ? 130 VAL N CG2 1 
ATOM   3941 N N   . CYS D 4 131 ? 219.458 176.699 181.451 1.00 138.86 ? 131 CYS N N   1 
ATOM   3942 C CA  . CYS D 4 131 ? 218.959 176.749 180.085 1.00 138.86 ? 131 CYS N CA  1 
ATOM   3943 C C   . CYS D 4 131 ? 217.449 176.564 180.124 1.00 138.86 ? 131 CYS N C   1 
ATOM   3944 O O   . CYS D 4 131 ? 216.873 176.236 181.165 1.00 138.86 ? 131 CYS N O   1 
ATOM   3945 C CB  . CYS D 4 131 ? 219.674 175.716 179.187 1.00 138.86 ? 131 CYS N CB  1 
ATOM   3946 S SG  . CYS D 4 131 ? 221.543 175.583 179.281 1.00 138.86 ? 131 CYS N SG  1 
ATOM   3947 N N   . GLU D 4 132 ? 216.796 176.806 178.986 1.00 145.33 ? 132 GLU N N   1 
ATOM   3948 C CA  . GLU D 4 132 ? 215.352 176.593 178.882 1.00 145.33 ? 132 GLU N CA  1 
ATOM   3949 C C   . GLU D 4 132 ? 215.138 175.106 178.639 1.00 145.33 ? 132 GLU N C   1 
ATOM   3950 O O   . GLU D 4 132 ? 214.969 174.653 177.506 1.00 145.33 ? 132 GLU N O   1 
ATOM   3951 C CB  . GLU D 4 132 ? 214.739 177.452 177.785 1.00 145.33 ? 132 GLU N CB  1 
ATOM   3952 C CG  . GLU D 4 132 ? 215.216 178.897 177.776 1.00 145.33 ? 132 GLU N CG  1 
ATOM   3953 C CD  . GLU D 4 132 ? 214.481 179.745 176.758 1.00 145.33 ? 132 GLU N CD  1 
ATOM   3954 O OE1 . GLU D 4 132 ? 214.021 179.187 175.739 1.00 145.33 ? 132 GLU N OE1 1 
ATOM   3955 O OE2 . GLU D 4 132 ? 214.362 180.968 176.974 1.00 145.33 ? 132 GLU N OE2 1 
ATOM   3956 N N   . PHE D 4 133 ? 215.147 174.340 179.725 1.00 142.88 ? 133 PHE N N   1 
ATOM   3957 C CA  . PHE D 4 133 ? 215.123 172.884 179.643 1.00 142.88 ? 133 PHE N CA  1 
ATOM   3958 C C   . PHE D 4 133 ? 213.700 172.399 179.389 1.00 142.88 ? 133 PHE N C   1 
ATOM   3959 O O   . PHE D 4 133 ? 212.737 172.973 179.911 1.00 142.88 ? 133 PHE N O   1 
ATOM   3960 C CB  . PHE D 4 133 ? 215.672 172.269 180.926 1.00 142.88 ? 133 PHE N CB  1 
ATOM   3961 C CG  . PHE D 4 133 ? 217.119 172.585 181.181 1.00 142.88 ? 133 PHE N CG  1 
ATOM   3962 C CD1 . PHE D 4 133 ? 218.119 171.958 180.460 1.00 142.88 ? 133 PHE N CD1 1 
ATOM   3963 C CD2 . PHE D 4 133 ? 217.477 173.494 182.161 1.00 142.88 ? 133 PHE N CD2 1 
ATOM   3964 C CE1 . PHE D 4 133 ? 219.448 172.247 180.698 1.00 142.88 ? 133 PHE N CE1 1 
ATOM   3965 C CE2 . PHE D 4 133 ? 218.803 173.786 182.406 1.00 142.88 ? 133 PHE N CE2 1 
ATOM   3966 C CZ  . PHE D 4 133 ? 219.790 173.162 181.675 1.00 142.88 ? 133 PHE N CZ  1 
ATOM   3967 N N   . GLN D 4 134 ? 213.572 171.351 178.585 1.00 149.88 ? 134 GLN N N   1 
ATOM   3968 C CA  . GLN D 4 134 ? 212.284 170.713 178.342 1.00 149.88 ? 134 GLN N CA  1 
ATOM   3969 C C   . GLN D 4 134 ? 212.182 169.394 179.098 1.00 149.88 ? 134 GLN N C   1 
ATOM   3970 O O   . GLN D 4 134 ? 212.512 168.336 178.563 1.00 149.88 ? 134 GLN N O   1 
ATOM   3971 C CB  . GLN D 4 134 ? 212.072 170.483 176.844 1.00 149.88 ? 134 GLN N CB  1 
ATOM   3972 C CG  . GLN D 4 134 ? 211.569 171.701 176.099 1.00 149.88 ? 134 GLN N CG  1 
ATOM   3973 C CD  . GLN D 4 134 ? 210.101 171.965 176.360 1.00 149.88 ? 134 GLN N CD  1 
ATOM   3974 O OE1 . GLN D 4 134 ? 209.743 172.831 177.155 1.00 149.88 ? 134 GLN N OE1 1 
ATOM   3975 N NE2 . GLN D 4 134 ? 209.238 171.212 175.684 1.00 149.88 ? 134 GLN N NE2 1 
ATOM   3976 N N   . TYR D 4 160 ? 216.991 166.246 179.855 1.00 163.06 ? 160 TYR N N   1 
ATOM   3977 C CA  . TYR D 4 160 ? 216.209 167.212 179.037 1.00 163.06 ? 160 TYR N CA  1 
ATOM   3978 C C   . TYR D 4 160 ? 216.091 166.738 177.591 1.00 163.06 ? 160 TYR N C   1 
ATOM   3979 O O   . TYR D 4 160 ? 216.856 165.843 177.176 1.00 163.06 ? 160 TYR N O   1 
ATOM   3980 C CB  . TYR D 4 160 ? 216.834 168.608 179.016 1.00 163.06 ? 160 TYR N CB  1 
ATOM   3981 C CG  . TYR D 4 160 ? 218.326 168.689 178.818 1.00 163.06 ? 160 TYR N CG  1 
ATOM   3982 C CD1 . TYR D 4 160 ? 219.196 168.566 179.888 1.00 163.06 ? 160 TYR N CD1 1 
ATOM   3983 C CD2 . TYR D 4 160 ? 218.869 168.941 177.570 1.00 163.06 ? 160 TYR N CD2 1 
ATOM   3984 C CE1 . TYR D 4 160 ? 220.566 168.656 179.724 1.00 163.06 ? 160 TYR N CE1 1 
ATOM   3985 C CE2 . TYR D 4 160 ? 220.238 169.032 177.386 1.00 163.06 ? 160 TYR N CE2 1 
ATOM   3986 C CZ  . TYR D 4 160 ? 221.089 168.892 178.467 1.00 163.06 ? 160 TYR N CZ  1 
ATOM   3987 O OH  . TYR D 4 160 ? 222.439 168.980 178.306 1.00 163.06 ? 160 TYR N OH  1 
ATOM   3988 N N   . SER D 4 161 ? 215.166 167.349 176.844 1.00 161.93 ? 161 SER N N   1 
ATOM   3989 C CA  . SER D 4 161 ? 214.974 166.979 175.417 1.00 161.93 ? 161 SER N CA  1 
ATOM   3990 C C   . SER D 4 161 ? 215.609 168.046 174.520 1.00 161.93 ? 161 SER N C   1 
ATOM   3991 O O   . SER D 4 161 ? 216.145 167.672 173.464 1.00 161.93 ? 161 SER N O   1 
ATOM   3992 C CB  . SER D 4 161 ? 213.515 166.767 175.097 1.00 161.93 ? 161 SER N CB  1 
ATOM   3993 O OG  . SER D 4 161 ? 212.895 167.966 174.660 1.00 161.93 ? 161 SER N OG  1 
ATOM   3994 N N   . SER D 4 162 ? 215.562 169.314 174.940 1.00 156.34 ? 162 SER N N   1 
ATOM   3995 C CA  . SER D 4 162 ? 216.102 170.419 174.110 1.00 156.34 ? 162 SER N CA  1 
ATOM   3996 C C   . SER D 4 162 ? 216.716 171.506 174.992 1.00 156.34 ? 162 SER N C   1 
ATOM   3997 O O   . SER D 4 162 ? 216.105 171.837 176.026 1.00 156.34 ? 162 SER N O   1 
ATOM   3998 C CB  . SER D 4 162 ? 215.022 170.991 173.246 1.00 156.34 ? 162 SER N CB  1 
ATOM   3999 O OG  . SER D 4 162 ? 215.559 171.931 172.329 1.00 156.34 ? 162 SER N OG  1 
ATOM   4000 N N   . ALA D 4 163 ? 217.861 172.051 174.578 1.00 153.05 ? 163 ALA N N   1 
ATOM   4001 C CA  . ALA D 4 163 ? 218.516 173.144 175.329 1.00 153.05 ? 163 ALA N CA  1 
ATOM   4002 C C   . ALA D 4 163 ? 218.675 174.349 174.409 1.00 153.05 ? 163 ALA N C   1 
ATOM   4003 O O   . ALA D 4 163 ? 219.515 174.277 173.499 1.00 153.05 ? 163 ALA N O   1 
ATOM   4004 C CB  . ALA D 4 163 ? 219.857 172.679 175.816 1.00 153.05 ? 163 ALA N CB  1 
ATOM   4005 N N   . ASN D 4 164 ? 217.868 175.387 174.594 1.00 150.25 ? 164 ASN N N   1 
ATOM   4006 C CA  . ASN D 4 164 ? 218.101 176.620 173.796 1.00 150.25 ? 164 ASN N CA  1 
ATOM   4007 C C   . ASN D 4 164 ? 218.534 177.735 174.761 1.00 150.25 ? 164 ASN N C   1 
ATOM   4008 O O   . ASN D 4 164 ? 218.429 177.501 175.986 1.00 150.25 ? 164 ASN N O   1 
ATOM   4009 C CB  . ASN D 4 164 ? 216.921 176.921 172.865 1.00 150.25 ? 164 ASN N CB  1 
ATOM   4010 C CG  . ASN D 4 164 ? 215.807 177.699 173.522 1.00 150.25 ? 164 ASN N CG  1 
ATOM   4011 O OD1 . ASN D 4 164 ? 215.759 178.922 173.418 1.00 150.25 ? 164 ASN N OD1 1 
ATOM   4012 N ND2 . ASN D 4 164 ? 214.901 176.995 174.180 1.00 150.25 ? 164 ASN N ND2 1 
ATOM   4013 N N   . ASN D 4 165 ? 219.046 178.859 174.241 1.00 146.55 ? 165 ASN N N   1 
ATOM   4014 C CA  . ASN D 4 165 ? 219.538 179.988 175.081 1.00 146.55 ? 165 ASN N CA  1 
ATOM   4015 C C   . ASN D 4 165 ? 220.854 179.583 175.762 1.00 146.55 ? 165 ASN N C   1 
ATOM   4016 O O   . ASN D 4 165 ? 221.899 179.916 175.189 1.00 146.55 ? 165 ASN N O   1 
ATOM   4017 C CB  . ASN D 4 165 ? 218.465 180.491 176.049 1.00 146.55 ? 165 ASN N CB  1 
ATOM   4018 C CG  . ASN D 4 165 ? 218.452 181.986 176.271 1.00 146.55 ? 165 ASN N CG  1 
ATOM   4019 O OD1 . ASN D 4 165 ? 219.447 182.672 176.047 1.00 146.55 ? 165 ASN N OD1 1 
ATOM   4020 N ND2 . ASN D 4 165 ? 217.313 182.487 176.717 1.00 146.55 ? 165 ASN N ND2 1 
ATOM   4021 N N   . CYS D 4 166 ? 220.812 178.891 176.907 1.00 139.02 ? 166 CYS N N   1 
ATOM   4022 C CA  . CYS D 4 166 ? 222.023 178.490 177.691 1.00 139.02 ? 166 CYS N CA  1 
ATOM   4023 C C   . CYS D 4 166 ? 222.886 179.723 178.000 1.00 139.02 ? 166 CYS N C   1 
ATOM   4024 O O   . CYS D 4 166 ? 223.901 179.929 177.312 1.00 139.02 ? 166 CYS N O   1 
ATOM   4025 C CB  . CYS D 4 166 ? 222.810 177.359 177.035 1.00 139.02 ? 166 CYS N CB  1 
ATOM   4026 S SG  . CYS D 4 166 ? 222.108 175.708 177.317 1.00 139.02 ? 166 CYS N SG  1 
ATOM   4027 N N   . THR D 4 167 ? 222.521 180.470 179.038 1.00 129.04 ? 167 THR N N   1 
ATOM   4028 C CA  . THR D 4 167 ? 223.219 181.708 179.477 1.00 129.04 ? 167 THR N CA  1 
ATOM   4029 C C   . THR D 4 167 ? 224.423 181.405 180.385 1.00 129.04 ? 167 THR N C   1 
ATOM   4030 O O   . THR D 4 167 ? 225.544 181.486 179.872 1.00 129.04 ? 167 THR N O   1 
ATOM   4031 C CB  . THR D 4 167 ? 222.224 182.678 180.124 1.00 129.04 ? 167 THR N CB  1 
ATOM   4032 O OG1 . THR D 4 167 ? 221.407 181.967 181.051 1.00 129.04 ? 167 THR N OG1 1 
ATOM   4033 C CG2 . THR D 4 167 ? 221.337 183.365 179.109 1.00 129.04 ? 167 THR N CG2 1 
ATOM   4034 N N   . PHE D 4 168 ? 224.224 181.097 181.666 1.00 117.76 ? 168 PHE N N   1 
ATOM   4035 C CA  . PHE D 4 168 ? 225.354 180.930 182.621 1.00 117.76 ? 168 PHE N CA  1 
ATOM   4036 C C   . PHE D 4 168 ? 225.724 179.459 182.790 1.00 117.76 ? 168 PHE N C   1 
ATOM   4037 O O   . PHE D 4 168 ? 224.808 178.634 182.732 1.00 117.76 ? 168 PHE N O   1 
ATOM   4038 C CB  . PHE D 4 168 ? 224.936 181.534 183.963 1.00 117.76 ? 168 PHE N CB  1 
ATOM   4039 C CG  . PHE D 4 168 ? 225.898 181.386 185.112 1.00 117.76 ? 168 PHE N CG  1 
ATOM   4040 C CD1 . PHE D 4 168 ? 226.947 182.273 185.276 1.00 117.76 ? 168 PHE N CD1 1 
ATOM   4041 C CD2 . PHE D 4 168 ? 225.730 180.384 186.052 1.00 117.76 ? 168 PHE N CD2 1 
ATOM   4042 C CE1 . PHE D 4 168 ? 227.826 182.145 186.340 1.00 117.76 ? 168 PHE N CE1 1 
ATOM   4043 C CE2 . PHE D 4 168 ? 226.610 180.257 187.112 1.00 117.76 ? 168 PHE N CE2 1 
ATOM   4044 C CZ  . PHE D 4 168 ? 227.655 181.137 187.257 1.00 117.76 ? 168 PHE N CZ  1 
ATOM   4045 N N   . GLU D 4 169 ? 227.013 179.138 182.968 1.00 117.93 ? 169 GLU N N   1 
ATOM   4046 C CA  . GLU D 4 169 ? 227.471 177.773 183.197 1.00 117.93 ? 169 GLU N CA  1 
ATOM   4047 C C   . GLU D 4 169 ? 228.604 177.814 184.208 1.00 117.93 ? 169 GLU N C   1 
ATOM   4048 O O   . GLU D 4 169 ? 229.578 178.550 184.019 1.00 117.93 ? 169 GLU N O   1 
ATOM   4049 C CB  . GLU D 4 169 ? 227.928 177.109 181.894 1.00 117.93 ? 169 GLU N CB  1 
ATOM   4050 C CG  . GLU D 4 169 ? 226.812 176.856 180.887 1.00 117.93 ? 169 GLU N CG  1 
ATOM   4051 C CD  . GLU D 4 169 ? 226.476 178.075 180.048 1.00 117.93 ? 169 GLU N CD  1 
ATOM   4052 O OE1 . GLU D 4 169 ? 227.156 179.113 180.200 1.00 117.93 ? 169 GLU N OE1 1 
ATOM   4053 O OE2 . GLU D 4 169 ? 225.528 177.997 179.237 1.00 117.93 ? 169 GLU N OE2 1 
ATOM   4054 N N   . TYR D 4 170 ? 228.479 177.028 185.274 1.00 113.88 ? 170 TYR N N   1 
ATOM   4055 C CA  . TYR D 4 170 ? 229.465 176.995 186.345 1.00 113.88 ? 170 TYR N CA  1 
ATOM   4056 C C   . TYR D 4 170 ? 229.997 175.579 186.487 1.00 113.88 ? 170 TYR N C   1 
ATOM   4057 O O   . TYR D 4 170 ? 229.228 174.613 186.481 1.00 113.88 ? 170 TYR N O   1 
ATOM   4058 C CB  . TYR D 4 170 ? 228.857 177.495 187.665 1.00 113.88 ? 170 TYR N CB  1 
ATOM   4059 C CG  . TYR D 4 170 ? 229.830 177.613 188.818 1.00 113.88 ? 170 TYR N CG  1 
ATOM   4060 C CD1 . TYR D 4 170 ? 230.246 178.857 189.269 1.00 113.88 ? 170 TYR N CD1 1 
ATOM   4061 C CD2 . TYR D 4 170 ? 230.296 176.488 189.486 1.00 113.88 ? 170 TYR N CD2 1 
ATOM   4062 C CE1 . TYR D 4 170 ? 231.126 178.975 190.325 1.00 113.88 ? 170 TYR N CE1 1 
ATOM   4063 C CE2 . TYR D 4 170 ? 231.173 176.597 190.541 1.00 113.88 ? 170 TYR N CE2 1 
ATOM   4064 C CZ  . TYR D 4 170 ? 231.585 177.842 190.960 1.00 113.88 ? 170 TYR N CZ  1 
ATOM   4065 O OH  . TYR D 4 170 ? 232.458 177.953 192.015 1.00 113.88 ? 170 TYR N OH  1 
ATOM   4066 N N   . VAL D 4 171 ? 231.318 175.458 186.607 1.00 119.40 ? 171 VAL N N   1 
ATOM   4067 C CA  . VAL D 4 171 ? 231.992 174.165 186.639 1.00 119.40 ? 171 VAL N CA  1 
ATOM   4068 C C   . VAL D 4 171 ? 233.053 174.194 187.735 1.00 119.40 ? 171 VAL N C   1 
ATOM   4069 O O   . VAL D 4 171 ? 233.992 174.991 187.668 1.00 119.40 ? 171 VAL N O   1 
ATOM   4070 C CB  . VAL D 4 171 ? 232.635 173.834 185.276 1.00 119.40 ? 171 VAL N CB  1 
ATOM   4071 C CG1 . VAL D 4 171 ? 233.561 172.638 185.397 1.00 119.40 ? 171 VAL N CG1 1 
ATOM   4072 C CG2 . VAL D 4 171 ? 231.564 173.593 184.218 1.00 119.40 ? 171 VAL N CG2 1 
ATOM   4073 N N   . SER D 4 172 ? 232.915 173.315 188.724 1.00 124.98 ? 172 SER N N   1 
ATOM   4074 C CA  . SER D 4 172 ? 233.897 173.213 189.804 1.00 124.98 ? 172 SER N CA  1 
ATOM   4075 C C   . SER D 4 172 ? 233.726 171.861 190.493 1.00 124.98 ? 172 SER N C   1 
ATOM   4076 O O   . SER D 4 172 ? 232.939 171.016 190.058 1.00 124.98 ? 172 SER N O   1 
ATOM   4077 C CB  . SER D 4 172 ? 233.759 174.376 190.787 1.00 124.98 ? 172 SER N CB  1 
ATOM   4078 O OG  . SER D 4 172 ? 234.944 174.549 191.545 1.00 124.98 ? 172 SER N OG  1 
ATOM   4079 N N   . GLN D 4 173 ? 234.454 171.667 191.593 1.00 127.57 ? 173 GLN N N   1 
ATOM   4080 C CA  . GLN D 4 173 ? 234.471 170.375 192.261 1.00 127.57 ? 173 GLN N CA  1 
ATOM   4081 C C   . GLN D 4 173 ? 233.088 170.031 192.814 1.00 127.57 ? 173 GLN N C   1 
ATOM   4082 O O   . GLN D 4 173 ? 232.320 170.919 193.191 1.00 127.57 ? 173 GLN N O   1 
ATOM   4083 C CB  . GLN D 4 173 ? 235.502 170.376 193.387 1.00 127.57 ? 173 GLN N CB  1 
ATOM   4084 C CG  . GLN D 4 173 ? 236.950 170.371 192.909 1.00 127.57 ? 173 GLN N CG  1 
ATOM   4085 C CD  . GLN D 4 173 ? 237.450 171.753 192.546 1.00 127.57 ? 173 GLN N CD  1 
ATOM   4086 O OE1 . GLN D 4 173 ? 236.845 172.759 192.919 1.00 127.57 ? 173 GLN N OE1 1 
ATOM   4087 N NE2 . GLN D 4 173 ? 238.568 171.813 191.830 1.00 127.57 ? 173 GLN N NE2 1 
ATOM   4088 N N   . PRO D 4 174 ? 232.747 168.743 192.874 1.00 126.60 ? 174 PRO N N   1 
ATOM   4089 C CA  . PRO D 4 174 ? 231.393 168.353 193.273 1.00 126.60 ? 174 PRO N CA  1 
ATOM   4090 C C   . PRO D 4 174 ? 231.113 168.697 194.726 1.00 126.60 ? 174 PRO N C   1 
ATOM   4091 O O   . PRO D 4 174 ? 232.016 168.840 195.554 1.00 126.60 ? 174 PRO N O   1 
ATOM   4092 C CB  . PRO D 4 174 ? 231.372 166.839 193.049 1.00 126.60 ? 174 PRO N CB  1 
ATOM   4093 C CG  . PRO D 4 174 ? 232.796 166.422 193.123 1.00 126.60 ? 174 PRO N CG  1 
ATOM   4094 C CD  . PRO D 4 174 ? 233.612 167.577 192.622 1.00 126.60 ? 174 PRO N CD  1 
ATOM   4095 N N   . PHE D 4 175 ? 229.825 168.832 195.024 1.00 110.52 ? 175 PHE N N   1 
ATOM   4096 C CA  . PHE D 4 175 ? 229.374 169.198 196.360 1.00 110.52 ? 175 PHE N CA  1 
ATOM   4097 C C   . PHE D 4 175 ? 229.598 168.051 197.338 1.00 110.52 ? 175 PHE N C   1 
ATOM   4098 O O   . PHE D 4 175 ? 229.061 166.958 197.162 1.00 110.52 ? 175 PHE N O   1 
ATOM   4099 C CB  . PHE D 4 175 ? 227.895 169.590 196.339 1.00 110.52 ? 175 PHE N CB  1 
ATOM   4100 C CG  . PHE D 4 175 ? 227.590 170.782 195.475 1.00 110.52 ? 175 PHE N CG  1 
ATOM   4101 C CD1 . PHE D 4 175 ? 226.291 171.052 195.087 1.00 110.52 ? 175 PHE N CD1 1 
ATOM   4102 C CD2 . PHE D 4 175 ? 228.599 171.628 195.046 1.00 110.52 ? 175 PHE N CD2 1 
ATOM   4103 C CE1 . PHE D 4 175 ? 226.000 172.145 194.295 1.00 110.52 ? 175 PHE N CE1 1 
ATOM   4104 C CE2 . PHE D 4 175 ? 228.315 172.722 194.251 1.00 110.52 ? 175 PHE N CE2 1 
ATOM   4105 C CZ  . PHE D 4 175 ? 227.014 172.980 193.877 1.00 110.52 ? 175 PHE N CZ  1 
ATOM   4106 N N   . LEU D 4 189 ? 226.154 162.671 206.860 1.00 98.40  ? 189 LEU N N   1 
ATOM   4107 C CA  . LEU D 4 189 ? 225.021 163.540 206.563 1.00 98.40  ? 189 LEU N CA  1 
ATOM   4108 C C   . LEU D 4 189 ? 225.424 164.697 205.656 1.00 98.40  ? 189 LEU N C   1 
ATOM   4109 O O   . LEU D 4 189 ? 226.411 165.385 205.912 1.00 98.40  ? 189 LEU N O   1 
ATOM   4110 C CB  . LEU D 4 189 ? 224.409 164.081 207.856 1.00 98.40  ? 189 LEU N CB  1 
ATOM   4111 C CG  . LEU D 4 189 ? 223.227 165.036 207.680 1.00 98.40  ? 189 LEU N CG  1 
ATOM   4112 C CD1 . LEU D 4 189 ? 222.080 164.350 206.956 1.00 98.40  ? 189 LEU N CD1 1 
ATOM   4113 C CD2 . LEU D 4 189 ? 222.769 165.578 209.023 1.00 98.40  ? 189 LEU N CD2 1 
ATOM   4114 N N   . ARG D 4 190 ? 224.646 164.907 204.595 1.00 92.98  ? 190 ARG N N   1 
ATOM   4115 C CA  . ARG D 4 190 ? 224.883 165.981 203.635 1.00 92.98  ? 190 ARG N CA  1 
ATOM   4116 C C   . ARG D 4 190 ? 223.651 166.876 203.625 1.00 92.98  ? 190 ARG N C   1 
ATOM   4117 O O   . ARG D 4 190 ? 222.565 166.429 203.246 1.00 92.98  ? 190 ARG N O   1 
ATOM   4118 C CB  . ARG D 4 190 ? 225.168 165.423 202.241 1.00 92.98  ? 190 ARG N CB  1 
ATOM   4119 C CG  . ARG D 4 190 ? 226.587 164.907 202.061 1.00 92.98  ? 190 ARG N CG  1 
ATOM   4120 C CD  . ARG D 4 190 ? 226.692 164.007 200.840 1.00 92.98  ? 190 ARG N CD  1 
ATOM   4121 N NE  . ARG D 4 190 ? 227.143 164.739 199.662 1.00 92.98  ? 190 ARG N NE  1 
ATOM   4122 C CZ  . ARG D 4 190 ? 226.393 164.976 198.594 1.00 92.98  ? 190 ARG N CZ  1 
ATOM   4123 N NH1 . ARG D 4 190 ? 225.141 164.560 198.524 1.00 92.98  ? 190 ARG N NH1 1 
ATOM   4124 N NH2 . ARG D 4 190 ? 226.914 165.652 197.575 1.00 92.98  ? 190 ARG N NH2 1 
ATOM   4125 N N   . GLU D 4 191 ? 223.819 168.129 204.032 1.00 80.03  ? 191 GLU N N   1 
ATOM   4126 C CA  . GLU D 4 191 ? 222.701 169.048 204.192 1.00 80.03  ? 191 GLU N CA  1 
ATOM   4127 C C   . GLU D 4 191 ? 222.982 170.369 203.489 1.00 80.03  ? 191 GLU N C   1 
ATOM   4128 O O   . GLU D 4 191 ? 224.109 170.872 203.514 1.00 80.03  ? 191 GLU N O   1 
ATOM   4129 C CB  . GLU D 4 191 ? 222.388 169.257 205.682 1.00 80.03  ? 191 GLU N CB  1 
ATOM   4130 C CG  . GLU D 4 191 ? 223.474 169.942 206.489 1.00 80.03  ? 191 GLU N CG  1 
ATOM   4131 C CD  . GLU D 4 191 ? 223.111 170.040 207.959 1.00 80.03  ? 191 GLU N CD  1 
ATOM   4132 O OE1 . GLU D 4 191 ? 222.023 169.557 208.330 1.00 80.03  ? 191 GLU N OE1 1 
ATOM   4133 O OE2 . GLU D 4 191 ? 223.918 170.572 208.750 1.00 80.03  ? 191 GLU N OE2 1 
ATOM   4134 N N   . PHE D 4 192 ? 221.946 170.919 202.852 1.00 78.61  ? 192 PHE N N   1 
ATOM   4135 C CA  . PHE D 4 192 ? 222.069 172.081 201.984 1.00 78.61  ? 192 PHE N CA  1 
ATOM   4136 C C   . PHE D 4 192 ? 220.954 173.071 202.286 1.00 78.61  ? 192 PHE N C   1 
ATOM   4137 O O   . PHE D 4 192 ? 219.856 172.688 202.693 1.00 78.61  ? 192 PHE N O   1 
ATOM   4138 C CB  . PHE D 4 192 ? 221.998 171.687 200.502 1.00 78.61  ? 192 PHE N CB  1 
ATOM   4139 C CG  . PHE D 4 192 ? 223.130 170.811 200.045 1.00 78.61  ? 192 PHE N CG  1 
ATOM   4140 C CD1 . PHE D 4 192 ? 224.277 171.362 199.505 1.00 78.61  ? 192 PHE N CD1 1 
ATOM   4141 C CD2 . PHE D 4 192 ? 223.042 169.434 200.156 1.00 78.61  ? 192 PHE N CD2 1 
ATOM   4142 C CE1 . PHE D 4 192 ? 225.315 170.556 199.082 1.00 78.61  ? 192 PHE N CE1 1 
ATOM   4143 C CE2 . PHE D 4 192 ? 224.079 168.623 199.738 1.00 78.61  ? 192 PHE N CE2 1 
ATOM   4144 C CZ  . PHE D 4 192 ? 225.218 169.186 199.199 1.00 78.61  ? 192 PHE N CZ  1 
ATOM   4145 N N   . VAL D 4 193 ? 221.246 174.353 202.073 1.00 69.17  ? 193 VAL N N   1 
ATOM   4146 C CA  . VAL D 4 193 ? 220.254 175.422 202.129 1.00 69.17  ? 193 VAL N CA  1 
ATOM   4147 C C   . VAL D 4 193 ? 220.349 176.233 200.846 1.00 69.17  ? 193 VAL N C   1 
ATOM   4148 O O   . VAL D 4 193 ? 221.438 176.673 200.462 1.00 69.17  ? 193 VAL N O   1 
ATOM   4149 C CB  . VAL D 4 193 ? 220.445 176.329 203.359 1.00 69.17  ? 193 VAL N CB  1 
ATOM   4150 C CG1 . VAL D 4 193 ? 219.492 177.507 203.292 1.00 69.17  ? 193 VAL N CG1 1 
ATOM   4151 C CG2 . VAL D 4 193 ? 220.180 175.548 204.621 1.00 69.17  ? 193 VAL N CG2 1 
ATOM   4152 N N   . PHE D 4 194 ? 219.208 176.430 200.190 1.00 74.40  ? 194 PHE N N   1 
ATOM   4153 C CA  . PHE D 4 194 ? 219.132 177.167 198.937 1.00 74.40  ? 194 PHE N CA  1 
ATOM   4154 C C   . PHE D 4 194 ? 218.214 178.364 199.115 1.00 74.40  ? 194 PHE N C   1 
ATOM   4155 O O   . PHE D 4 194 ? 217.076 178.216 199.572 1.00 74.40  ? 194 PHE N O   1 
ATOM   4156 C CB  . PHE D 4 194 ? 218.614 176.274 197.806 1.00 74.40  ? 194 PHE N CB  1 
ATOM   4157 C CG  . PHE D 4 194 ? 219.408 175.018 197.616 1.00 74.40  ? 194 PHE N CG  1 
ATOM   4158 C CD1 . PHE D 4 194 ? 220.721 175.067 197.190 1.00 74.40  ? 194 PHE N CD1 1 
ATOM   4159 C CD2 . PHE D 4 194 ? 218.837 173.782 197.868 1.00 74.40  ? 194 PHE N CD2 1 
ATOM   4160 C CE1 . PHE D 4 194 ? 221.452 173.910 197.020 1.00 74.40  ? 194 PHE N CE1 1 
ATOM   4161 C CE2 . PHE D 4 194 ? 219.562 172.621 197.698 1.00 74.40  ? 194 PHE N CE2 1 
ATOM   4162 C CZ  . PHE D 4 194 ? 220.872 172.685 197.273 1.00 74.40  ? 194 PHE N CZ  1 
ATOM   4163 N N   . LYS D 4 195 ? 218.705 179.548 198.759 1.00 73.36  ? 195 LYS N N   1 
ATOM   4164 C CA  . LYS D 4 195 ? 217.883 180.747 198.736 1.00 73.36  ? 195 LYS N CA  1 
ATOM   4165 C C   . LYS D 4 195 ? 218.205 181.545 197.483 1.00 73.36  ? 195 LYS N C   1 
ATOM   4166 O O   . LYS D 4 195 ? 219.351 181.578 197.027 1.00 73.36  ? 195 LYS N O   1 
ATOM   4167 C CB  . LYS D 4 195 ? 218.093 181.622 199.975 1.00 73.36  ? 195 LYS N CB  1 
ATOM   4168 C CG  . LYS D 4 195 ? 219.542 181.941 200.278 1.00 73.36  ? 195 LYS N CG  1 
ATOM   4169 C CD  . LYS D 4 195 ? 219.645 183.167 201.166 1.00 73.36  ? 195 LYS N CD  1 
ATOM   4170 C CE  . LYS D 4 195 ? 218.856 182.985 202.445 1.00 73.36  ? 195 LYS N CE  1 
ATOM   4171 N NZ  . LYS D 4 195 ? 219.053 184.124 203.382 1.00 73.36  ? 195 LYS N NZ  1 
ATOM   4172 N N   . ASN D 4 196 ? 217.179 182.189 196.931 1.00 86.39  ? 196 ASN N N   1 
ATOM   4173 C CA  . ASN D 4 196 ? 217.284 182.941 195.680 1.00 86.39  ? 196 ASN N CA  1 
ATOM   4174 C C   . ASN D 4 196 ? 216.757 184.348 195.936 1.00 86.39  ? 196 ASN N C   1 
ATOM   4175 O O   . ASN D 4 196 ? 215.551 184.593 195.854 1.00 86.39  ? 196 ASN N O   1 
ATOM   4176 C CB  . ASN D 4 196 ? 216.519 182.240 194.563 1.00 86.39  ? 196 ASN N CB  1 
ATOM   4177 C CG  . ASN D 4 196 ? 216.672 182.935 193.228 1.00 86.39  ? 196 ASN N CG  1 
ATOM   4178 O OD1 . ASN D 4 196 ? 217.767 183.352 192.852 1.00 86.39  ? 196 ASN N OD1 1 
ATOM   4179 N ND2 . ASN D 4 196 ? 215.569 183.069 192.501 1.00 86.39  ? 196 ASN N ND2 1 
ATOM   4180 N N   . ILE D 4 197 ? 217.664 185.275 196.241 1.00 92.16  ? 197 ILE N N   1 
ATOM   4181 C CA  . ILE D 4 197 ? 217.310 186.647 196.570 1.00 92.16  ? 197 ILE N CA  1 
ATOM   4182 C C   . ILE D 4 197 ? 218.116 187.599 195.697 1.00 92.16  ? 197 ILE N C   1 
ATOM   4183 O O   . ILE D 4 197 ? 219.295 187.355 195.419 1.00 92.16  ? 197 ILE N O   1 
ATOM   4184 C CB  . ILE D 4 197 ? 217.538 186.955 198.066 1.00 92.16  ? 197 ILE N CB  1 
ATOM   4185 C CG1 . ILE D 4 197 ? 219.016 186.800 198.435 1.00 92.16  ? 197 ILE N CG1 1 
ATOM   4186 C CG2 . ILE D 4 197 ? 216.671 186.057 198.936 1.00 92.16  ? 197 ILE N CG2 1 
ATOM   4187 C CD1 . ILE D 4 197 ? 219.357 187.302 199.818 1.00 92.16  ? 197 ILE N CD1 1 
ATOM   4188 N N   . ASP D 4 198 ? 217.464 188.674 195.246 1.00 96.45  ? 198 ASP N N   1 
ATOM   4189 C CA  . ASP D 4 198 ? 218.115 189.755 194.503 1.00 96.45  ? 198 ASP N CA  1 
ATOM   4190 C C   . ASP D 4 198 ? 218.816 189.241 193.248 1.00 96.45  ? 198 ASP N C   1 
ATOM   4191 O O   . ASP D 4 198 ? 219.878 189.734 192.862 1.00 96.45  ? 198 ASP N O   1 
ATOM   4192 C CB  . ASP D 4 198 ? 219.095 190.520 195.394 1.00 96.45  ? 198 ASP N CB  1 
ATOM   4193 C CG  . ASP D 4 198 ? 218.398 191.464 196.350 1.00 96.45  ? 198 ASP N CG  1 
ATOM   4194 O OD1 . ASP D 4 198 ? 217.311 191.967 196.000 1.00 96.45  ? 198 ASP N OD1 1 
ATOM   4195 O OD2 . ASP D 4 198 ? 218.937 191.701 197.451 1.00 96.45  ? 198 ASP N OD2 1 
ATOM   4196 N N   . GLY D 4 199 ? 218.224 188.238 192.609 1.00 98.61  ? 199 GLY N N   1 
ATOM   4197 C CA  . GLY D 4 199 ? 218.808 187.643 191.427 1.00 98.61  ? 199 GLY N CA  1 
ATOM   4198 C C   . GLY D 4 199 ? 219.989 186.738 191.690 1.00 98.61  ? 199 GLY N C   1 
ATOM   4199 O O   . GLY D 4 199 ? 220.529 186.161 190.738 1.00 98.61  ? 199 GLY N O   1 
ATOM   4200 N N   . TYR D 4 200 ? 220.411 186.595 192.939 1.00 93.50  ? 200 TYR N N   1 
ATOM   4201 C CA  . TYR D 4 200 ? 221.501 185.708 193.305 1.00 93.50  ? 200 TYR N CA  1 
ATOM   4202 C C   . TYR D 4 200 ? 220.947 184.422 193.898 1.00 93.50  ? 200 TYR N C   1 
ATOM   4203 O O   . TYR D 4 200 ? 219.954 184.429 194.628 1.00 93.50  ? 200 TYR N O   1 
ATOM   4204 C CB  . TYR D 4 200 ? 222.438 186.372 194.313 1.00 93.50  ? 200 TYR N CB  1 
ATOM   4205 C CG  . TYR D 4 200 ? 223.387 187.377 193.712 1.00 93.50  ? 200 TYR N CG  1 
ATOM   4206 C CD1 . TYR D 4 200 ? 222.974 188.671 193.430 1.00 93.50  ? 200 TYR N CD1 1 
ATOM   4207 C CD2 . TYR D 4 200 ? 224.701 187.033 193.426 1.00 93.50  ? 200 TYR N CD2 1 
ATOM   4208 C CE1 . TYR D 4 200 ? 223.839 189.595 192.884 1.00 93.50  ? 200 TYR N CE1 1 
ATOM   4209 C CE2 . TYR D 4 200 ? 225.575 187.947 192.878 1.00 93.50  ? 200 TYR N CE2 1 
ATOM   4210 C CZ  . TYR D 4 200 ? 225.140 189.225 192.609 1.00 93.50  ? 200 TYR N CZ  1 
ATOM   4211 O OH  . TYR D 4 200 ? 226.012 190.138 192.063 1.00 93.50  ? 200 TYR N OH  1 
ATOM   4212 N N   . PHE D 4 201 ? 221.603 183.316 193.577 1.00 84.20  ? 201 PHE N N   1 
ATOM   4213 C CA  . PHE D 4 201 ? 221.237 182.007 194.102 1.00 84.20  ? 201 PHE N CA  1 
ATOM   4214 C C   . PHE D 4 201 ? 222.353 181.536 195.030 1.00 84.20  ? 201 PHE N C   1 
ATOM   4215 O O   . PHE D 4 201 ? 223.443 181.185 194.569 1.00 84.20  ? 201 PHE N O   1 
ATOM   4216 C CB  . PHE D 4 201 ? 220.991 181.015 192.972 1.00 84.20  ? 201 PHE N CB  1 
ATOM   4217 C CG  . PHE D 4 201 ? 220.635 179.652 193.450 1.00 84.20  ? 201 PHE N CG  1 
ATOM   4218 C CD1 . PHE D 4 201 ? 219.338 179.350 193.810 1.00 84.20  ? 201 PHE N CD1 1 
ATOM   4219 C CD2 . PHE D 4 201 ? 221.601 178.667 193.543 1.00 84.20  ? 201 PHE N CD2 1 
ATOM   4220 C CE1 . PHE D 4 201 ? 219.016 178.099 194.260 1.00 84.20  ? 201 PHE N CE1 1 
ATOM   4221 C CE2 . PHE D 4 201 ? 221.280 177.412 193.985 1.00 84.20  ? 201 PHE N CE2 1 
ATOM   4222 C CZ  . PHE D 4 201 ? 219.992 177.127 194.349 1.00 84.20  ? 201 PHE N CZ  1 
ATOM   4223 N N   . LYS D 4 202 ? 222.069 181.514 196.327 1.00 75.35  ? 202 LYS N N   1 
ATOM   4224 C CA  . LYS D 4 202 ? 223.069 181.260 197.354 1.00 75.35  ? 202 LYS N CA  1 
ATOM   4225 C C   . LYS D 4 202 ? 222.927 179.841 197.886 1.00 75.35  ? 202 LYS N C   1 
ATOM   4226 O O   . LYS D 4 202 ? 221.811 179.341 198.058 1.00 75.35  ? 202 LYS N O   1 
ATOM   4227 C CB  . LYS D 4 202 ? 222.926 182.270 198.493 1.00 75.35  ? 202 LYS N CB  1 
ATOM   4228 C CG  . LYS D 4 202 ? 223.143 183.705 198.047 1.00 75.35  ? 202 LYS N CG  1 
ATOM   4229 C CD  . LYS D 4 202 ? 223.045 184.682 199.202 1.00 75.35  ? 202 LYS N CD  1 
ATOM   4230 C CE  . LYS D 4 202 ? 223.250 186.109 198.720 1.00 75.35  ? 202 LYS N CE  1 
ATOM   4231 N NZ  . LYS D 4 202 ? 223.172 187.092 199.832 1.00 75.35  ? 202 LYS N NZ  1 
ATOM   4232 N N   . ILE D 4 203 ? 224.062 179.193 198.142 1.00 72.12  ? 203 ILE N N   1 
ATOM   4233 C CA  . ILE D 4 203 ? 224.092 177.806 198.591 1.00 72.12  ? 203 ILE N CA  1 
ATOM   4234 C C   . ILE D 4 203 ? 224.958 177.707 199.838 1.00 72.12  ? 203 ILE N C   1 
ATOM   4235 O O   . ILE D 4 203 ? 226.032 178.312 199.903 1.00 72.12  ? 203 ILE N O   1 
ATOM   4236 C CB  . ILE D 4 203 ? 224.624 176.857 197.499 1.00 72.12  ? 203 ILE N CB  1 
ATOM   4237 C CG1 . ILE D 4 203 ? 223.807 176.996 196.218 1.00 72.12  ? 203 ILE N CG1 1 
ATOM   4238 C CG2 . ILE D 4 203 ? 224.587 175.414 197.977 1.00 72.12  ? 203 ILE N CG2 1 
ATOM   4239 C CD1 . ILE D 4 203 ? 224.541 176.539 194.980 1.00 72.12  ? 203 ILE N CD1 1 
ATOM   4240 N N   . TYR D 4 204 ? 224.491 176.945 200.824 1.00 61.54  ? 204 TYR N N   1 
ATOM   4241 C CA  . TYR D 4 204 ? 225.253 176.632 202.021 1.00 61.54  ? 204 TYR N CA  1 
ATOM   4242 C C   . TYR D 4 204 ? 225.193 175.128 202.249 1.00 61.54  ? 204 TYR N C   1 
ATOM   4243 O O   . TYR D 4 204 ? 224.151 174.501 202.054 1.00 61.54  ? 204 TYR N O   1 
ATOM   4244 C CB  . TYR D 4 204 ? 224.714 177.386 203.245 1.00 61.54  ? 204 TYR N CB  1 
ATOM   4245 C CG  . TYR D 4 204 ? 224.414 178.845 202.976 1.00 61.54  ? 204 TYR N CG  1 
ATOM   4246 C CD1 . TYR D 4 204 ? 223.204 179.235 202.418 1.00 61.54  ? 204 TYR N CD1 1 
ATOM   4247 C CD2 . TYR D 4 204 ? 225.339 179.830 203.284 1.00 61.54  ? 204 TYR N CD2 1 
ATOM   4248 C CE1 . TYR D 4 204 ? 222.933 180.567 202.170 1.00 61.54  ? 204 TYR N CE1 1 
ATOM   4249 C CE2 . TYR D 4 204 ? 225.076 181.160 203.040 1.00 61.54  ? 204 TYR N CE2 1 
ATOM   4250 C CZ  . TYR D 4 204 ? 223.871 181.522 202.483 1.00 61.54  ? 204 TYR N CZ  1 
ATOM   4251 O OH  . TYR D 4 204 ? 223.606 182.847 202.239 1.00 61.54  ? 204 TYR N OH  1 
ATOM   4252 N N   . SER D 4 205 ? 226.321 174.549 202.657 1.00 65.42  ? 205 SER N N   1 
ATOM   4253 C CA  . SER D 4 205 ? 226.425 173.097 202.696 1.00 65.42  ? 205 SER N CA  1 
ATOM   4254 C C   . SER D 4 205 ? 227.278 172.652 203.874 1.00 65.42  ? 205 SER N C   1 
ATOM   4255 O O   . SER D 4 205 ? 228.052 173.428 204.440 1.00 65.42  ? 205 SER N O   1 
ATOM   4256 C CB  . SER D 4 205 ? 227.016 172.549 201.392 1.00 65.42  ? 205 SER N CB  1 
ATOM   4257 O OG  . SER D 4 205 ? 228.431 172.600 201.414 1.00 65.42  ? 205 SER N OG  1 
ATOM   4258 N N   . LYS D 4 206 ? 227.122 171.380 204.230 1.00 65.41  ? 206 LYS N N   1 
ATOM   4259 C CA  . LYS D 4 206 ? 227.938 170.729 205.247 1.00 65.41  ? 206 LYS N CA  1 
ATOM   4260 C C   . LYS D 4 206 ? 227.810 169.212 205.140 1.00 65.41  ? 206 LYS N C   1 
ATOM   4261 O O   . LYS D 4 206 ? 228.803 168.486 205.206 1.00 65.41  ? 206 LYS N O   1 
ATOM   4262 C CB  . LYS D 4 206 ? 227.539 171.188 206.649 1.00 65.41  ? 206 LYS N CB  1 
ATOM   4263 C CG  . LYS D 4 206 ? 228.240 170.438 207.767 1.00 65.41  ? 206 LYS N CG  1 
ATOM   4264 C CD  . LYS D 4 206 ? 229.699 170.840 207.872 1.00 65.41  ? 206 LYS N CD  1 
ATOM   4265 C CE  . LYS D 4 206 ? 229.841 172.266 208.369 1.00 65.41  ? 206 LYS N CE  1 
ATOM   4266 N NZ  . LYS D 4 206 ? 229.496 172.378 209.812 1.00 65.41  ? 206 LYS N NZ  1 
ATOM   4267 N N   . SER D 4 221 ? 226.131 172.419 213.730 1.00 62.38  ? 221 SER N N   1 
ATOM   4268 C CA  . SER D 4 221 ? 225.524 172.840 212.472 1.00 62.38  ? 221 SER N CA  1 
ATOM   4269 C C   . SER D 4 221 ? 226.443 173.802 211.725 1.00 62.38  ? 221 SER N C   1 
ATOM   4270 O O   . SER D 4 221 ? 227.469 173.390 211.187 1.00 62.38  ? 221 SER N O   1 
ATOM   4271 C CB  . SER D 4 221 ? 224.166 173.489 212.726 1.00 62.38  ? 221 SER N CB  1 
ATOM   4272 O OG  . SER D 4 221 ? 223.565 173.902 211.512 1.00 62.38  ? 221 SER N OG  1 
ATOM   4273 N N   . ALA D 4 222 ? 226.061 175.083 211.696 1.00 61.94  ? 222 ALA N N   1 
ATOM   4274 C CA  . ALA D 4 222 ? 226.883 176.140 211.118 1.00 61.94  ? 222 ALA N CA  1 
ATOM   4275 C C   . ALA D 4 222 ? 227.211 175.879 209.653 1.00 61.94  ? 222 ALA N C   1 
ATOM   4276 O O   . ALA D 4 222 ? 228.374 175.654 209.306 1.00 61.94  ? 222 ALA N O   1 
ATOM   4277 C CB  . ALA D 4 222 ? 228.173 176.316 211.920 1.00 61.94  ? 222 ALA N CB  1 
ATOM   4278 N N   . LEU D 4 223 ? 226.196 175.895 208.792 1.00 63.34  ? 223 LEU N N   1 
ATOM   4279 C CA  . LEU D 4 223 ? 226.384 175.636 207.367 1.00 63.34  ? 223 LEU N CA  1 
ATOM   4280 C C   . LEU D 4 223 ? 227.255 176.727 206.756 1.00 63.34  ? 223 LEU N C   1 
ATOM   4281 O O   . LEU D 4 223 ? 226.834 177.883 206.649 1.00 63.34  ? 223 LEU N O   1 
ATOM   4282 C CB  . LEU D 4 223 ? 225.037 175.551 206.659 1.00 63.34  ? 223 LEU N CB  1 
ATOM   4283 C CG  . LEU D 4 223 ? 224.090 174.550 207.311 1.00 63.34  ? 223 LEU N CG  1 
ATOM   4284 C CD1 . LEU D 4 223 ? 222.830 174.406 206.501 1.00 63.34  ? 223 LEU N CD1 1 
ATOM   4285 C CD2 . LEU D 4 223 ? 224.783 173.221 207.448 1.00 63.34  ? 223 LEU N CD2 1 
ATOM   4286 N N   . GLU D 4 224 ? 228.463 176.355 206.346 1.00 63.80  ? 224 GLU N N   1 
ATOM   4287 C CA  . GLU D 4 224 ? 229.357 177.307 205.708 1.00 63.80  ? 224 GLU N CA  1 
ATOM   4288 C C   . GLU D 4 224 ? 228.848 177.640 204.307 1.00 63.80  ? 224 GLU N C   1 
ATOM   4289 O O   . GLU D 4 224 ? 228.242 176.792 203.647 1.00 63.80  ? 224 GLU N O   1 
ATOM   4290 C CB  . GLU D 4 224 ? 230.771 176.736 205.631 1.00 63.80  ? 224 GLU N CB  1 
ATOM   4291 C CG  . GLU D 4 224 ? 231.602 176.974 206.878 1.00 63.80  ? 224 GLU N CG  1 
ATOM   4292 C CD  . GLU D 4 224 ? 233.019 176.455 206.743 1.00 63.80  ? 224 GLU N CD  1 
ATOM   4293 O OE1 . GLU D 4 224 ? 233.545 175.895 207.728 1.00 63.80  ? 224 GLU N OE1 1 
ATOM   4294 O OE2 . GLU D 4 224 ? 233.605 176.605 205.652 1.00 63.80  ? 224 GLU N OE2 1 
ATOM   4295 N N   . PRO D 4 225 ? 229.068 178.865 203.830 1.00 64.58  ? 225 PRO N N   1 
ATOM   4296 C CA  . PRO D 4 225 ? 228.627 179.218 202.474 1.00 64.58  ? 225 PRO N CA  1 
ATOM   4297 C C   . PRO D 4 225 ? 229.400 178.437 201.424 1.00 64.58  ? 225 PRO N C   1 
ATOM   4298 O O   . PRO D 4 225 ? 230.631 178.454 201.389 1.00 64.58  ? 225 PRO N O   1 
ATOM   4299 C CB  . PRO D 4 225 ? 228.916 180.722 202.388 1.00 64.58  ? 225 PRO N CB  1 
ATOM   4300 C CG  . PRO D 4 225 ? 228.996 181.180 203.801 1.00 64.58  ? 225 PRO N CG  1 
ATOM   4301 C CD  . PRO D 4 225 ? 229.585 180.032 204.561 1.00 64.58  ? 225 PRO N CD  1 
ATOM   4302 N N   . LEU D 4 226 ? 228.660 177.742 200.561 1.00 75.04  ? 226 LEU N N   1 
ATOM   4303 C CA  . LEU D 4 226 ? 229.294 176.988 199.482 1.00 75.04  ? 226 LEU N CA  1 
ATOM   4304 C C   . LEU D 4 226 ? 229.627 177.906 198.314 1.00 75.04  ? 226 LEU N C   1 
ATOM   4305 O O   . LEU D 4 226 ? 230.799 178.092 197.968 1.00 75.04  ? 226 LEU N O   1 
ATOM   4306 C CB  . LEU D 4 226 ? 228.379 175.839 199.043 1.00 75.04  ? 226 LEU N CB  1 
ATOM   4307 C CG  . LEU D 4 226 ? 228.904 174.919 197.944 1.00 75.04  ? 226 LEU N CG  1 
ATOM   4308 C CD1 . LEU D 4 226 ? 230.210 174.271 198.367 1.00 75.04  ? 226 LEU N CD1 1 
ATOM   4309 C CD2 . LEU D 4 226 ? 227.866 173.864 197.620 1.00 75.04  ? 226 LEU N CD2 1 
ATOM   4310 N N   . VAL D 4 227 ? 228.606 178.501 197.701 1.00 81.46  ? 227 VAL N N   1 
ATOM   4311 C CA  . VAL D 4 227 ? 228.794 179.402 196.571 1.00 81.46  ? 227 VAL N CA  1 
ATOM   4312 C C   . VAL D 4 227 ? 227.480 180.118 196.304 1.00 81.46  ? 227 VAL N C   1 
ATOM   4313 O O   . VAL D 4 227 ? 226.402 179.570 196.554 1.00 81.46  ? 227 VAL N O   1 
ATOM   4314 C CB  . VAL D 4 227 ? 229.291 178.611 195.332 1.00 81.46  ? 227 VAL N CB  1 
ATOM   4315 C CG1 . VAL D 4 227 ? 228.234 177.627 194.865 1.00 81.46  ? 227 VAL N CG1 1 
ATOM   4316 C CG2 . VAL D 4 227 ? 229.690 179.557 194.208 1.00 81.46  ? 227 VAL N CG2 1 
ATOM   4317 N N   . ASP D 4 228 ? 227.566 181.353 195.808 1.00 88.41  ? 228 ASP N N   1 
ATOM   4318 C CA  . ASP D 4 228 ? 226.405 182.086 195.331 1.00 88.41  ? 228 ASP N CA  1 
ATOM   4319 C C   . ASP D 4 228 ? 226.583 182.390 193.853 1.00 88.41  ? 228 ASP N C   1 
ATOM   4320 O O   . ASP D 4 228 ? 227.699 182.614 193.376 1.00 88.41  ? 228 ASP N O   1 
ATOM   4321 C CB  . ASP D 4 228 ? 226.167 183.386 196.117 1.00 88.41  ? 228 ASP N CB  1 
ATOM   4322 C CG  . ASP D 4 228 ? 227.337 184.343 196.045 1.00 88.41  ? 228 ASP N CG  1 
ATOM   4323 O OD1 . ASP D 4 228 ? 228.438 183.922 195.638 1.00 88.41  ? 228 ASP N OD1 1 
ATOM   4324 O OD2 . ASP D 4 228 ? 227.149 185.530 196.387 1.00 88.41  ? 228 ASP N OD2 1 
ATOM   4325 N N   . LEU D 4 229 ? 225.471 182.375 193.120 1.00 94.78  ? 229 LEU N N   1 
ATOM   4326 C CA  . LEU D 4 229 ? 225.516 182.390 191.667 1.00 94.78  ? 229 LEU N CA  1 
ATOM   4327 C C   . LEU D 4 229 ? 224.635 183.512 191.133 1.00 94.78  ? 229 LEU N C   1 
ATOM   4328 O O   . LEU D 4 229 ? 223.478 183.649 191.564 1.00 94.78  ? 229 LEU N O   1 
ATOM   4329 C CB  . LEU D 4 229 ? 225.065 181.037 191.100 1.00 94.78  ? 229 LEU N CB  1 
ATOM   4330 C CG  . LEU D 4 229 ? 226.061 179.875 191.148 1.00 94.78  ? 229 LEU N CG  1 
ATOM   4331 C CD1 . LEU D 4 229 ? 226.264 179.362 192.555 1.00 94.78  ? 229 LEU N CD1 1 
ATOM   4332 C CD2 . LEU D 4 229 ? 225.574 178.752 190.283 1.00 94.78  ? 229 LEU N CD2 1 
ATOM   4333 N N   . PRO D 4 230 ? 225.130 184.325 190.201 1.00 102.62 ? 230 PRO N N   1 
ATOM   4334 C CA  . PRO D 4 230 ? 224.296 185.383 189.618 1.00 102.62 ? 230 PRO N CA  1 
ATOM   4335 C C   . PRO D 4 230 ? 223.323 184.850 188.579 1.00 102.62 ? 230 PRO N C   1 
ATOM   4336 O O   . PRO D 4 230 ? 223.389 185.237 187.408 1.00 102.62 ? 230 PRO N O   1 
ATOM   4337 C CB  . PRO D 4 230 ? 225.325 186.326 188.986 1.00 102.62 ? 230 PRO N CB  1 
ATOM   4338 C CG  . PRO D 4 230 ? 226.479 185.441 188.654 1.00 102.62 ? 230 PRO N CG  1 
ATOM   4339 C CD  . PRO D 4 230 ? 226.524 184.383 189.722 1.00 102.62 ? 230 PRO N CD  1 
ATOM   4340 N N   . ILE D 4 231 ? 222.415 183.963 188.992 1.00 101.32 ? 231 ILE N N   1 
ATOM   4341 C CA  . ILE D 4 231 ? 221.504 183.332 188.042 1.00 101.32 ? 231 ILE N CA  1 
ATOM   4342 C C   . ILE D 4 231 ? 220.523 184.356 187.483 1.00 101.32 ? 231 ILE N C   1 
ATOM   4343 O O   . ILE D 4 231 ? 220.323 184.450 186.267 1.00 101.32 ? 231 ILE N O   1 
ATOM   4344 C CB  . ILE D 4 231 ? 220.775 182.152 188.706 1.00 101.32 ? 231 ILE N CB  1 
ATOM   4345 C CG1 . ILE D 4 231 ? 221.780 181.175 189.310 1.00 101.32 ? 231 ILE N CG1 1 
ATOM   4346 C CG2 . ILE D 4 231 ? 219.924 181.425 187.686 1.00 101.32 ? 231 ILE N CG2 1 
ATOM   4347 C CD1 . ILE D 4 231 ? 222.776 180.638 188.314 1.00 101.32 ? 231 ILE N CD1 1 
ATOM   4348 N N   . GLY D 4 232 ? 219.902 185.141 188.361 1.00 101.59 ? 232 GLY N N   1 
ATOM   4349 C CA  . GLY D 4 232 ? 218.980 186.181 187.943 1.00 101.59 ? 232 GLY N CA  1 
ATOM   4350 C C   . GLY D 4 232 ? 217.701 185.702 187.284 1.00 101.59 ? 232 GLY N C   1 
ATOM   4351 O O   . GLY D 4 232 ? 217.269 186.277 186.282 1.00 101.59 ? 232 GLY N O   1 
ATOM   4352 N N   . ILE D 4 233 ? 217.081 184.652 187.831 1.00 103.24 ? 233 ILE N N   1 
ATOM   4353 C CA  . ILE D 4 233 ? 215.790 184.175 187.354 1.00 103.24 ? 233 ILE N CA  1 
ATOM   4354 C C   . ILE D 4 233 ? 214.879 183.946 188.553 1.00 103.24 ? 233 ILE N C   1 
ATOM   4355 O O   . ILE D 4 233 ? 215.331 183.811 189.691 1.00 103.24 ? 233 ILE N O   1 
ATOM   4356 C CB  . ILE D 4 233 ? 215.891 182.873 186.528 1.00 103.24 ? 233 ILE N CB  1 
ATOM   4357 C CG1 . ILE D 4 233 ? 216.449 181.741 187.387 1.00 103.24 ? 233 ILE N CG1 1 
ATOM   4358 C CG2 . ILE D 4 233 ? 216.754 183.087 185.292 1.00 103.24 ? 233 ILE N CG2 1 
ATOM   4359 C CD1 . ILE D 4 233 ? 216.365 180.383 186.734 1.00 103.24 ? 233 ILE N CD1 1 
ATOM   4360 N N   . ASN D 4 234 ? 213.577 183.906 188.279 1.00 96.65  ? 234 ASN N N   1 
ATOM   4361 C CA  . ASN D 4 234 ? 212.591 183.601 189.306 1.00 96.65  ? 234 ASN N CA  1 
ATOM   4362 C C   . ASN D 4 234 ? 212.567 182.098 189.557 1.00 96.65  ? 234 ASN N C   1 
ATOM   4363 O O   . ASN D 4 234 ? 212.761 181.306 188.629 1.00 96.65  ? 234 ASN N O   1 
ATOM   4364 C CB  . ASN D 4 234 ? 211.209 184.093 188.882 1.00 96.65  ? 234 ASN N CB  1 
ATOM   4365 C CG  . ASN D 4 234 ? 211.065 185.597 188.997 1.00 96.65  ? 234 ASN N CG  1 
ATOM   4366 O OD1 . ASN D 4 234 ? 211.648 186.221 189.883 1.00 96.65  ? 234 ASN N OD1 1 
ATOM   4367 N ND2 . ASN D 4 234 ? 210.286 186.188 188.099 1.00 96.65  ? 234 ASN N ND2 1 
ATOM   4368 N N   . ILE D 4 235 ? 212.349 181.704 190.811 1.00 95.92  ? 235 ILE N N   1 
ATOM   4369 C CA  . ILE D 4 235 ? 212.368 180.296 191.192 1.00 95.92  ? 235 ILE N CA  1 
ATOM   4370 C C   . ILE D 4 235 ? 211.214 180.066 192.162 1.00 95.92  ? 235 ILE N C   1 
ATOM   4371 O O   . ILE D 4 235 ? 211.138 180.729 193.204 1.00 95.92  ? 235 ILE N O   1 
ATOM   4372 C CB  . ILE D 4 235 ? 213.706 179.902 191.838 1.00 95.92  ? 235 ILE N CB  1 
ATOM   4373 C CG1 . ILE D 4 235 ? 214.832 179.995 190.805 1.00 95.92  ? 235 ILE N CG1 1 
ATOM   4374 C CG2 . ILE D 4 235 ? 213.625 178.493 192.407 1.00 95.92  ? 235 ILE N CG2 1 
ATOM   4375 C CD1 . ILE D 4 235 ? 215.018 178.784 189.956 1.00 95.92  ? 235 ILE N CD1 1 
ATOM   4376 N N   . THR D 4 236 ? 210.315 179.138 191.823 1.00 96.42  ? 236 THR N N   1 
ATOM   4377 C CA  . THR D 4 236 ? 209.120 178.896 192.624 1.00 96.42  ? 236 THR N CA  1 
ATOM   4378 C C   . THR D 4 236 ? 208.895 177.437 193.000 1.00 96.42  ? 236 THR N C   1 
ATOM   4379 O O   . THR D 4 236 ? 208.330 177.173 194.063 1.00 96.42  ? 236 THR N O   1 
ATOM   4380 C CB  . THR D 4 236 ? 207.864 179.391 191.892 1.00 96.42  ? 236 THR N CB  1 
ATOM   4381 O OG1 . THR D 4 236 ? 207.553 178.498 190.814 1.00 96.42  ? 236 THR N OG1 1 
ATOM   4382 C CG2 . THR D 4 236 ? 208.069 180.796 191.339 1.00 96.42  ? 236 THR N CG2 1 
ATOM   4383 N N   . ARG D 4 237 ? 209.310 176.491 192.163 1.00 98.53  ? 237 ARG N N   1 
ATOM   4384 C CA  . ARG D 4 237 ? 209.065 175.073 192.391 1.00 98.53  ? 237 ARG N CA  1 
ATOM   4385 C C   . ARG D 4 237 ? 210.342 174.303 192.076 1.00 98.53  ? 237 ARG N C   1 
ATOM   4386 O O   . ARG D 4 237 ? 211.173 174.753 191.284 1.00 98.53  ? 237 ARG N O   1 
ATOM   4387 C CB  . ARG D 4 237 ? 207.858 174.609 191.555 1.00 98.53  ? 237 ARG N CB  1 
ATOM   4388 C CG  . ARG D 4 237 ? 208.056 174.720 190.048 1.00 98.53  ? 237 ARG N CG  1 
ATOM   4389 C CD  . ARG D 4 237 ? 206.817 174.282 189.250 1.00 98.53  ? 237 ARG N CD  1 
ATOM   4390 N NE  . ARG D 4 237 ? 206.515 172.860 189.351 1.00 98.53  ? 237 ARG N NE  1 
ATOM   4391 C CZ  . ARG D 4 237 ? 205.366 172.308 188.990 1.00 98.53  ? 237 ARG N CZ  1 
ATOM   4392 N NH1 . ARG D 4 237 ? 204.376 173.031 188.492 1.00 98.53  ? 237 ARG N NH1 1 
ATOM   4393 N NH2 . ARG D 4 237 ? 205.209 170.993 189.121 1.00 98.53  ? 237 ARG N NH2 1 
ATOM   4394 N N   . PHE D 4 238 ? 210.515 173.146 192.718 1.00 97.07  ? 238 PHE N N   1 
ATOM   4395 C CA  . PHE D 4 238 ? 211.790 172.451 192.601 1.00 97.07  ? 238 PHE N CA  1 
ATOM   4396 C C   . PHE D 4 238 ? 211.608 170.945 192.730 1.00 97.07  ? 238 PHE N C   1 
ATOM   4397 O O   . PHE D 4 238 ? 210.597 170.456 193.242 1.00 97.07  ? 238 PHE N O   1 
ATOM   4398 C CB  . PHE D 4 238 ? 212.807 172.960 193.636 1.00 97.07  ? 238 PHE N CB  1 
ATOM   4399 C CG  . PHE D 4 238 ? 212.779 172.246 194.965 1.00 97.07  ? 238 PHE N CG  1 
ATOM   4400 C CD1 . PHE D 4 238 ? 211.749 172.435 195.864 1.00 97.07  ? 238 PHE N CD1 1 
ATOM   4401 C CD2 . PHE D 4 238 ? 213.815 171.389 195.315 1.00 97.07  ? 238 PHE N CD2 1 
ATOM   4402 C CE1 . PHE D 4 238 ? 211.753 171.785 197.087 1.00 97.07  ? 238 PHE N CE1 1 
ATOM   4403 C CE2 . PHE D 4 238 ? 213.819 170.733 196.529 1.00 97.07  ? 238 PHE N CE2 1 
ATOM   4404 C CZ  . PHE D 4 238 ? 212.785 170.928 197.416 1.00 97.07  ? 238 PHE N CZ  1 
ATOM   4405 N N   . GLN D 4 239 ? 212.617 170.214 192.253 1.00 95.87  ? 239 GLN N N   1 
ATOM   4406 C CA  . GLN D 4 239 ? 212.604 168.759 192.205 1.00 95.87  ? 239 GLN N CA  1 
ATOM   4407 C C   . GLN D 4 239 ? 214.022 168.244 192.400 1.00 95.87  ? 239 GLN N C   1 
ATOM   4408 O O   . GLN D 4 239 ? 214.985 168.884 191.970 1.00 95.87  ? 239 GLN N O   1 
ATOM   4409 C CB  . GLN D 4 239 ? 211.987 168.274 190.874 1.00 95.87  ? 239 GLN N CB  1 
ATOM   4410 C CG  . GLN D 4 239 ? 211.825 166.758 190.676 1.00 95.87  ? 239 GLN N CG  1 
ATOM   4411 C CD  . GLN D 4 239 ? 213.100 166.025 190.278 1.00 95.87  ? 239 GLN N CD  1 
ATOM   4412 O OE1 . GLN D 4 239 ? 214.162 166.624 190.122 1.00 95.87  ? 239 GLN N OE1 1 
ATOM   4413 N NE2 . GLN D 4 239 ? 212.991 164.713 190.111 1.00 95.87  ? 239 GLN N NE2 1 
ATOM   4414 N N   . THR D 4 240 ? 214.144 167.089 193.052 1.00 99.18  ? 240 THR N N   1 
ATOM   4415 C CA  . THR D 4 240 ? 215.449 166.507 193.341 1.00 99.18  ? 240 THR N CA  1 
ATOM   4416 C C   . THR D 4 240 ? 215.840 165.491 192.273 1.00 99.18  ? 240 THR N C   1 
ATOM   4417 O O   . THR D 4 240 ? 215.113 164.529 192.014 1.00 99.18  ? 240 THR N O   1 
ATOM   4418 C CB  . THR D 4 240 ? 215.444 165.833 194.712 1.00 99.18  ? 240 THR N CB  1 
ATOM   4419 O OG1 . THR D 4 240 ? 215.392 166.834 195.737 1.00 99.18  ? 240 THR N OG1 1 
ATOM   4420 C CG2 . THR D 4 240 ? 216.698 164.987 194.900 1.00 99.18  ? 240 THR N CG2 1 
ATOM   4421 N N   . LEU D 4 241 ? 217.001 165.709 191.662 1.00 102.12 ? 241 LEU N N   1 
ATOM   4422 C CA  . LEU D 4 241 ? 217.497 164.821 190.617 1.00 102.12 ? 241 LEU N CA  1 
ATOM   4423 C C   . LEU D 4 241 ? 218.046 163.536 191.227 1.00 102.12 ? 241 LEU N C   1 
ATOM   4424 O O   . LEU D 4 241 ? 219.096 163.537 191.864 1.00 102.12 ? 241 LEU N O   1 
ATOM   4425 C CB  . LEU D 4 241 ? 218.568 165.531 189.781 1.00 102.12 ? 241 LEU N CB  1 
ATOM   4426 C CG  . LEU D 4 241 ? 219.124 164.877 188.512 1.00 102.12 ? 241 LEU N CG  1 
ATOM   4427 C CD1 . LEU D 4 241 ? 219.606 165.952 187.557 1.00 102.12 ? 241 LEU N CD1 1 
ATOM   4428 C CD2 . LEU D 4 241 ? 220.267 163.920 188.819 1.00 102.12 ? 241 LEU N CD2 1 
ATOM   4429 N N   . TYR D 4 262 ? 214.900 161.940 201.341 1.00 100.82 ? 265 TYR N N   1 
ATOM   4430 C CA  . TYR D 4 262 ? 215.567 163.175 201.735 1.00 100.82 ? 265 TYR N CA  1 
ATOM   4431 C C   . TYR D 4 262 ? 214.630 164.079 202.531 1.00 100.82 ? 265 TYR N C   1 
ATOM   4432 O O   . TYR D 4 262 ? 213.410 163.981 202.407 1.00 100.82 ? 265 TYR N O   1 
ATOM   4433 C CB  . TYR D 4 262 ? 216.090 163.918 200.504 1.00 100.82 ? 265 TYR N CB  1 
ATOM   4434 C CG  . TYR D 4 262 ? 215.086 164.028 199.379 1.00 100.82 ? 265 TYR N CG  1 
ATOM   4435 C CD1 . TYR D 4 262 ? 214.089 164.993 199.404 1.00 100.82 ? 265 TYR N CD1 1 
ATOM   4436 C CD2 . TYR D 4 262 ? 215.137 163.167 198.291 1.00 100.82 ? 265 TYR N CD2 1 
ATOM   4437 C CE1 . TYR D 4 262 ? 213.171 165.099 198.379 1.00 100.82 ? 265 TYR N CE1 1 
ATOM   4438 C CE2 . TYR D 4 262 ? 214.222 163.265 197.260 1.00 100.82 ? 265 TYR N CE2 1 
ATOM   4439 C CZ  . TYR D 4 262 ? 213.243 164.234 197.309 1.00 100.82 ? 265 TYR N CZ  1 
ATOM   4440 O OH  . TYR D 4 262 ? 212.329 164.336 196.288 1.00 100.82 ? 265 TYR N OH  1 
ATOM   4441 N N   . TYR D 4 263 ? 215.208 164.956 203.344 1.00 99.22  ? 266 TYR N N   1 
ATOM   4442 C CA  . TYR D 4 263 ? 214.434 165.881 204.162 1.00 99.22  ? 266 TYR N CA  1 
ATOM   4443 C C   . TYR D 4 263 ? 214.348 167.236 203.475 1.00 99.22  ? 266 TYR N C   1 
ATOM   4444 O O   . TYR D 4 263 ? 215.350 167.756 202.976 1.00 99.22  ? 266 TYR N O   1 
ATOM   4445 C CB  . TYR D 4 263 ? 215.073 166.040 205.542 1.00 99.22  ? 266 TYR N CB  1 
ATOM   4446 C CG  . TYR D 4 263 ? 215.321 164.741 206.269 1.00 99.22  ? 266 TYR N CG  1 
ATOM   4447 C CD1 . TYR D 4 263 ? 214.325 164.146 207.029 1.00 99.22  ? 266 TYR N CD1 1 
ATOM   4448 C CD2 . TYR D 4 263 ? 216.559 164.114 206.207 1.00 99.22  ? 266 TYR N CD2 1 
ATOM   4449 C CE1 . TYR D 4 263 ? 214.551 162.958 207.699 1.00 99.22  ? 266 TYR N CE1 1 
ATOM   4450 C CE2 . TYR D 4 263 ? 216.796 162.929 206.872 1.00 99.22  ? 266 TYR N CE2 1 
ATOM   4451 C CZ  . TYR D 4 263 ? 215.789 162.354 207.617 1.00 99.22  ? 266 TYR N CZ  1 
ATOM   4452 O OH  . TYR D 4 263 ? 216.022 161.172 208.285 1.00 99.22  ? 266 TYR N OH  1 
ATOM   4453 N N   . VAL D 4 264 ? 213.147 167.807 203.450 1.00 92.80  ? 267 VAL N N   1 
ATOM   4454 C CA  . VAL D 4 264 ? 212.911 169.103 202.827 1.00 92.80  ? 267 VAL N CA  1 
ATOM   4455 C C   . VAL D 4 264 ? 212.186 170.006 203.814 1.00 92.80  ? 267 VAL N C   1 
ATOM   4456 O O   . VAL D 4 264 ? 211.082 169.680 204.263 1.00 92.80  ? 267 VAL N O   1 
ATOM   4457 C CB  . VAL D 4 264 ? 212.102 168.976 201.522 1.00 92.80  ? 267 VAL N CB  1 
ATOM   4458 C CG1 . VAL D 4 264 ? 211.609 170.341 201.075 1.00 92.80  ? 267 VAL N CG1 1 
ATOM   4459 C CG2 . VAL D 4 264 ? 212.944 168.326 200.438 1.00 92.80  ? 267 VAL N CG2 1 
ATOM   4460 N N   . GLY D 4 265 ? 212.809 171.138 204.151 1.00 84.04  ? 268 GLY N N   1 
ATOM   4461 C CA  . GLY D 4 265 ? 212.179 172.153 204.967 1.00 84.04  ? 268 GLY N CA  1 
ATOM   4462 C C   . GLY D 4 265 ? 212.104 173.472 204.219 1.00 84.04  ? 268 GLY N C   1 
ATOM   4463 O O   . GLY D 4 265 ? 212.646 173.617 203.124 1.00 84.04  ? 268 GLY N O   1 
ATOM   4464 N N   . TYR D 4 266 ? 211.441 174.440 204.851 1.00 75.58  ? 269 TYR N N   1 
ATOM   4465 C CA  . TYR D 4 266 ? 211.169 175.738 204.248 1.00 75.58  ? 269 TYR N CA  1 
ATOM   4466 C C   . TYR D 4 266 ? 211.608 176.854 205.186 1.00 75.58  ? 269 TYR N C   1 
ATOM   4467 O O   . TYR D 4 266 ? 211.400 176.788 206.400 1.00 75.58  ? 269 TYR N O   1 
ATOM   4468 C CB  . TYR D 4 266 ? 209.675 175.904 203.911 1.00 75.58  ? 269 TYR N CB  1 
ATOM   4469 C CG  . TYR D 4 266 ? 209.160 175.019 202.794 1.00 75.58  ? 269 TYR N CG  1 
ATOM   4470 C CD1 . TYR D 4 266 ? 210.030 174.364 201.935 1.00 75.58  ? 269 TYR N CD1 1 
ATOM   4471 C CD2 . TYR D 4 266 ? 207.798 174.819 202.618 1.00 75.58  ? 269 TYR N CD2 1 
ATOM   4472 C CE1 . TYR D 4 266 ? 209.561 173.552 200.919 1.00 75.58  ? 269 TYR N CE1 1 
ATOM   4473 C CE2 . TYR D 4 266 ? 207.319 174.010 201.603 1.00 75.58  ? 269 TYR N CE2 1 
ATOM   4474 C CZ  . TYR D 4 266 ? 208.205 173.378 200.758 1.00 75.58  ? 269 TYR N CZ  1 
ATOM   4475 O OH  . TYR D 4 266 ? 207.734 172.570 199.748 1.00 75.58  ? 269 TYR N OH  1 
ATOM   4476 N N   . LEU D 4 267 ? 212.207 177.888 204.603 1.00 65.29  ? 270 LEU N N   1 
ATOM   4477 C CA  . LEU D 4 267 ? 212.799 178.981 205.360 1.00 65.29  ? 270 LEU N CA  1 
ATOM   4478 C C   . LEU D 4 267 ? 211.750 180.025 205.727 1.00 65.29  ? 270 LEU N C   1 
ATOM   4479 O O   . LEU D 4 267 ? 210.776 180.240 205.000 1.00 65.29  ? 270 LEU N O   1 
ATOM   4480 C CB  . LEU D 4 267 ? 213.927 179.634 204.563 1.00 65.29  ? 270 LEU N CB  1 
ATOM   4481 C CG  . LEU D 4 267 ? 215.350 179.193 204.906 1.00 65.29  ? 270 LEU N CG  1 
ATOM   4482 C CD1 . LEU D 4 267 ? 215.516 177.691 204.738 1.00 65.29  ? 270 LEU N CD1 1 
ATOM   4483 C CD2 . LEU D 4 267 ? 216.353 179.939 204.048 1.00 65.29  ? 270 LEU N CD2 1 
ATOM   4484 N N   . GLN D 4 268 ? 211.966 180.677 206.865 1.00 65.70  ? 271 GLN N N   1 
ATOM   4485 C CA  . GLN D 4 268 ? 211.037 181.639 207.429 1.00 65.70  ? 271 GLN N CA  1 
ATOM   4486 C C   . GLN D 4 268 ? 211.782 182.904 207.828 1.00 65.70  ? 271 GLN N C   1 
ATOM   4487 O O   . GLN D 4 268 ? 212.888 182.834 208.376 1.00 65.70  ? 271 GLN N O   1 
ATOM   4488 C CB  . GLN D 4 268 ? 210.325 181.048 208.656 1.00 65.70  ? 271 GLN N CB  1 
ATOM   4489 C CG  . GLN D 4 268 ? 209.182 181.882 209.201 1.00 65.70  ? 271 GLN N CG  1 
ATOM   4490 C CD  . GLN D 4 268 ? 207.974 181.875 208.287 1.00 65.70  ? 271 GLN N CD  1 
ATOM   4491 O OE1 . GLN D 4 268 ? 207.660 180.863 207.663 1.00 65.70  ? 271 GLN N OE1 1 
ATOM   4492 N NE2 . GLN D 4 268 ? 207.285 183.009 208.207 1.00 65.70  ? 271 GLN N NE2 1 
ATOM   4493 N N   . PRO D 4 269 ? 211.204 184.078 207.566 1.00 57.87  ? 272 PRO N N   1 
ATOM   4494 C CA  . PRO D 4 269 ? 211.877 185.336 207.926 1.00 57.87  ? 272 PRO N CA  1 
ATOM   4495 C C   . PRO D 4 269 ? 211.728 185.698 209.395 1.00 57.87  ? 272 PRO N C   1 
ATOM   4496 O O   . PRO D 4 269 ? 210.824 186.456 209.756 1.00 57.87  ? 272 PRO N O   1 
ATOM   4497 C CB  . PRO D 4 269 ? 211.187 186.376 207.030 1.00 57.87  ? 272 PRO N CB  1 
ATOM   4498 C CG  . PRO D 4 269 ? 210.343 185.593 206.059 1.00 57.87  ? 272 PRO N CG  1 
ATOM   4499 C CD  . PRO D 4 269 ? 210.012 184.312 206.740 1.00 57.87  ? 272 PRO N CD  1 
ATOM   4500 N N   . ARG D 4 270 ? 212.603 185.172 210.251 1.00 55.74  ? 273 ARG N N   1 
ATOM   4501 C CA  . ARG D 4 270 ? 212.522 185.413 211.684 1.00 55.74  ? 273 ARG N CA  1 
ATOM   4502 C C   . ARG D 4 270 ? 213.874 185.864 212.223 1.00 55.74  ? 273 ARG N C   1 
ATOM   4503 O O   . ARG D 4 270 ? 214.922 185.577 211.640 1.00 55.74  ? 273 ARG N O   1 
ATOM   4504 C CB  . ARG D 4 270 ? 212.053 184.161 212.432 1.00 55.74  ? 273 ARG N CB  1 
ATOM   4505 C CG  . ARG D 4 270 ? 210.559 183.886 212.305 1.00 55.74  ? 273 ARG N CG  1 
ATOM   4506 C CD  . ARG D 4 270 ? 210.091 182.506 212.817 1.00 55.74  ? 273 ARG N CD  1 
ATOM   4507 N NE  . ARG D 4 270 ? 210.615 182.126 214.124 1.00 55.74  ? 273 ARG N NE  1 
ATOM   4508 C CZ  . ARG D 4 270 ? 211.824 181.626 214.353 1.00 55.74  ? 273 ARG N CZ  1 
ATOM   4509 N NH1 . ARG D 4 270 ? 212.618 181.250 213.365 1.00 55.74  ? 273 ARG N NH1 1 
ATOM   4510 N NH2 . ARG D 4 270 ? 212.234 181.479 215.608 1.00 55.74  ? 273 ARG N NH2 1 
ATOM   4511 N N   . THR D 4 271 ? 213.835 186.587 213.342 1.00 53.75  ? 274 THR N N   1 
ATOM   4512 C CA  . THR D 4 271 ? 215.045 187.084 213.983 1.00 53.75  ? 274 THR N CA  1 
ATOM   4513 C C   . THR D 4 271 ? 215.768 185.966 214.722 1.00 53.75  ? 274 THR N C   1 
ATOM   4514 O O   . THR D 4 271 ? 215.143 185.112 215.355 1.00 53.75  ? 274 THR N O   1 
ATOM   4515 C CB  . THR D 4 271 ? 214.707 188.210 214.963 1.00 53.75  ? 274 THR N CB  1 
ATOM   4516 O OG1 . THR D 4 271 ? 213.831 189.152 214.329 1.00 53.75  ? 274 THR N OG1 1 
ATOM   4517 C CG2 . THR D 4 271 ? 215.969 188.926 215.417 1.00 53.75  ? 274 THR N CG2 1 
ATOM   4518 N N   . PHE D 4 272 ? 217.097 185.984 214.649 1.00 51.30  ? 275 PHE N N   1 
ATOM   4519 C CA  . PHE D 4 272 ? 217.946 184.979 215.276 1.00 51.30  ? 275 PHE N CA  1 
ATOM   4520 C C   . PHE D 4 272 ? 219.016 185.651 216.122 1.00 51.30  ? 275 PHE N C   1 
ATOM   4521 O O   . PHE D 4 272 ? 219.341 186.826 215.939 1.00 51.30  ? 275 PHE N O   1 
ATOM   4522 C CB  . PHE D 4 272 ? 218.612 184.076 214.229 1.00 51.30  ? 275 PHE N CB  1 
ATOM   4523 C CG  . PHE D 4 272 ? 217.848 182.824 213.924 1.00 51.30  ? 275 PHE N CG  1 
ATOM   4524 C CD1 . PHE D 4 272 ? 216.484 182.862 213.694 1.00 51.30  ? 275 PHE N CD1 1 
ATOM   4525 C CD2 . PHE D 4 272 ? 218.500 181.609 213.857 1.00 51.30  ? 275 PHE N CD2 1 
ATOM   4526 C CE1 . PHE D 4 272 ? 215.792 181.705 213.414 1.00 51.30  ? 275 PHE N CE1 1 
ATOM   4527 C CE2 . PHE D 4 272 ? 217.813 180.452 213.574 1.00 51.30  ? 275 PHE N CE2 1 
ATOM   4528 C CZ  . PHE D 4 272 ? 216.456 180.499 213.351 1.00 51.30  ? 275 PHE N CZ  1 
ATOM   4529 N N   . LEU D 4 273 ? 219.564 184.882 217.059 1.00 47.64  ? 276 LEU N N   1 
ATOM   4530 C CA  . LEU D 4 273 ? 220.724 185.284 217.844 1.00 47.64  ? 276 LEU N CA  1 
ATOM   4531 C C   . LEU D 4 273 ? 221.791 184.216 217.677 1.00 47.64  ? 276 LEU N C   1 
ATOM   4532 O O   . LEU D 4 273 ? 221.518 183.030 217.880 1.00 47.64  ? 276 LEU N O   1 
ATOM   4533 C CB  . LEU D 4 273 ? 220.372 185.460 219.322 1.00 47.64  ? 276 LEU N CB  1 
ATOM   4534 C CG  . LEU D 4 273 ? 221.480 186.033 220.207 1.00 47.64  ? 276 LEU N CG  1 
ATOM   4535 C CD1 . LEU D 4 273 ? 221.852 187.433 219.754 1.00 47.64  ? 276 LEU N CD1 1 
ATOM   4536 C CD2 . LEU D 4 273 ? 221.059 186.031 221.662 1.00 47.64  ? 276 LEU N CD2 1 
ATOM   4537 N N   . LEU D 4 274 ? 223.000 184.632 217.306 1.00 45.09  ? 277 LEU N N   1 
ATOM   4538 C CA  . LEU D 4 274 ? 224.045 183.710 216.882 1.00 45.09  ? 277 LEU N CA  1 
ATOM   4539 C C   . LEU D 4 274 ? 225.293 183.934 217.720 1.00 45.09  ? 277 LEU N C   1 
ATOM   4540 O O   . LEU D 4 274 ? 225.786 185.060 217.813 1.00 45.09  ? 277 LEU N O   1 
ATOM   4541 C CB  . LEU D 4 274 ? 224.346 183.899 215.396 1.00 45.09  ? 277 LEU N CB  1 
ATOM   4542 C CG  . LEU D 4 274 ? 223.141 183.531 214.531 1.00 45.09  ? 277 LEU N CG  1 
ATOM   4543 C CD1 . LEU D 4 274 ? 223.387 183.843 213.077 1.00 45.09  ? 277 LEU N CD1 1 
ATOM   4544 C CD2 . LEU D 4 274 ? 222.799 182.071 214.720 1.00 45.09  ? 277 LEU N CD2 1 
ATOM   4545 N N   . LYS D 4 275 ? 225.804 182.861 218.320 1.00 45.55  ? 278 LYS N N   1 
ATOM   4546 C CA  . LYS D 4 275 ? 226.977 182.943 219.184 1.00 45.55  ? 278 LYS N CA  1 
ATOM   4547 C C   . LYS D 4 275 ? 228.218 182.560 218.390 1.00 45.55  ? 278 LYS N C   1 
ATOM   4548 O O   . LYS D 4 275 ? 228.464 181.381 218.125 1.00 45.55  ? 278 LYS N O   1 
ATOM   4549 C CB  . LYS D 4 275 ? 226.816 182.042 220.403 1.00 45.55  ? 278 LYS N CB  1 
ATOM   4550 C CG  . LYS D 4 275 ? 227.934 182.199 221.420 1.00 45.55  ? 278 LYS N CG  1 
ATOM   4551 C CD  . LYS D 4 275 ? 227.747 181.271 222.603 1.00 45.55  ? 278 LYS N CD  1 
ATOM   4552 C CE  . LYS D 4 275 ? 228.152 179.852 222.251 1.00 45.55  ? 278 LYS N CE  1 
ATOM   4553 N NZ  . LYS D 4 275 ? 228.124 178.958 223.441 1.00 45.55  ? 278 LYS N NZ  1 
ATOM   4554 N N   . TYR D 4 276 ? 229.008 183.557 218.008 1.00 47.53  ? 279 TYR N N   1 
ATOM   4555 C CA  . TYR D 4 276 ? 230.296 183.298 217.390 1.00 47.53  ? 279 TYR N CA  1 
ATOM   4556 C C   . TYR D 4 276 ? 231.316 182.903 218.458 1.00 47.53  ? 279 TYR N C   1 
ATOM   4557 O O   . TYR D 4 276 ? 231.216 183.282 219.627 1.00 47.53  ? 279 TYR N O   1 
ATOM   4558 C CB  . TYR D 4 276 ? 230.744 184.516 216.588 1.00 47.53  ? 279 TYR N CB  1 
ATOM   4559 C CG  . TYR D 4 276 ? 229.842 184.796 215.405 1.00 47.53  ? 279 TYR N CG  1 
ATOM   4560 C CD1 . TYR D 4 276 ? 228.616 185.425 215.572 1.00 47.53  ? 279 TYR N CD1 1 
ATOM   4561 C CD2 . TYR D 4 276 ? 230.222 184.433 214.122 1.00 47.53  ? 279 TYR N CD2 1 
ATOM   4562 C CE1 . TYR D 4 276 ? 227.792 185.675 214.495 1.00 47.53  ? 279 TYR N CE1 1 
ATOM   4563 C CE2 . TYR D 4 276 ? 229.406 184.687 213.040 1.00 47.53  ? 279 TYR N CE2 1 
ATOM   4564 C CZ  . TYR D 4 276 ? 228.192 185.304 213.231 1.00 47.53  ? 279 TYR N CZ  1 
ATOM   4565 O OH  . TYR D 4 276 ? 227.376 185.554 212.154 1.00 47.53  ? 279 TYR N OH  1 
ATOM   4566 N N   . ASN D 4 277 ? 232.322 182.132 218.035 1.00 52.64  ? 280 ASN N N   1 
ATOM   4567 C CA  . ASN D 4 277 ? 233.138 181.347 218.959 1.00 52.64  ? 280 ASN N CA  1 
ATOM   4568 C C   . ASN D 4 277 ? 234.621 181.646 218.720 1.00 52.64  ? 280 ASN N C   1 
ATOM   4569 O O   . ASN D 4 277 ? 235.424 180.754 218.461 1.00 52.64  ? 280 ASN N O   1 
ATOM   4570 C CB  . ASN D 4 277 ? 232.839 179.854 218.815 1.00 52.64  ? 280 ASN N CB  1 
ATOM   4571 C CG  . ASN D 4 277 ? 233.553 179.016 219.856 1.00 52.64  ? 280 ASN N CG  1 
ATOM   4572 O OD1 . ASN D 4 277 ? 233.831 179.483 220.960 1.00 52.64  ? 280 ASN N OD1 1 
ATOM   4573 N ND2 . ASN D 4 277 ? 233.861 177.774 219.506 1.00 52.64  ? 280 ASN N ND2 1 
ATOM   4574 N N   . GLU D 4 278 ? 234.961 182.935 218.719 1.00 57.51  ? 281 GLU N N   1 
ATOM   4575 C CA  . GLU D 4 278 ? 236.317 183.485 218.738 1.00 57.51  ? 281 GLU N CA  1 
ATOM   4576 C C   . GLU D 4 278 ? 237.109 183.165 217.474 1.00 57.51  ? 281 GLU N C   1 
ATOM   4577 O O   . GLU D 4 278 ? 238.231 183.657 217.310 1.00 57.51  ? 281 GLU N O   1 
ATOM   4578 C CB  . GLU D 4 278 ? 237.118 183.042 219.978 1.00 57.51  ? 281 GLU N CB  1 
ATOM   4579 C CG  . GLU D 4 278 ? 237.767 181.663 219.911 1.00 57.51  ? 281 GLU N CG  1 
ATOM   4580 C CD  . GLU D 4 278 ? 238.356 181.224 221.236 1.00 57.51  ? 281 GLU N CD  1 
ATOM   4581 O OE1 . GLU D 4 278 ? 238.281 182.002 222.210 1.00 57.51  ? 281 GLU N OE1 1 
ATOM   4582 O OE2 . GLU D 4 278 ? 238.887 180.095 221.305 1.00 57.51  ? 281 GLU N OE2 1 
ATOM   4583 N N   . ASN D 4 279 ? 236.560 182.347 216.579 1.00 56.55  ? 282 ASN N N   1 
ATOM   4584 C CA  . ASN D 4 279 ? 237.128 182.153 215.253 1.00 56.55  ? 282 ASN N CA  1 
ATOM   4585 C C   . ASN D 4 279 ? 236.005 182.069 214.227 1.00 56.55  ? 282 ASN N C   1 
ATOM   4586 O O   . ASN D 4 279 ? 236.032 181.216 213.335 1.00 56.55  ? 282 ASN N O   1 
ATOM   4587 C CB  . ASN D 4 279 ? 238.013 180.903 215.220 1.00 56.55  ? 282 ASN N CB  1 
ATOM   4588 C CG  . ASN D 4 279 ? 237.294 179.662 215.707 1.00 56.55  ? 282 ASN N CG  1 
ATOM   4589 O OD1 . ASN D 4 279 ? 236.092 179.683 215.967 1.00 56.55  ? 282 ASN N OD1 1 
ATOM   4590 N ND2 . ASN D 4 279 ? 238.035 178.566 215.836 1.00 56.55  ? 282 ASN N ND2 1 
ATOM   4591 N N   . GLY D 4 280 ? 235.018 182.953 214.346 1.00 53.81  ? 283 GLY N N   1 
ATOM   4592 C CA  . GLY D 4 280 ? 233.791 182.802 213.591 1.00 53.81  ? 283 GLY N CA  1 
ATOM   4593 C C   . GLY D 4 280 ? 233.022 181.609 214.112 1.00 53.81  ? 283 GLY N C   1 
ATOM   4594 O O   . GLY D 4 280 ? 232.693 181.558 215.301 1.00 53.81  ? 283 GLY N O   1 
ATOM   4595 N N   . THR D 4 281 ? 232.743 180.637 213.240 1.00 53.70  ? 284 THR N N   1 
ATOM   4596 C CA  . THR D 4 281 ? 232.218 179.335 213.646 1.00 53.70  ? 284 THR N CA  1 
ATOM   4597 C C   . THR D 4 281 ? 230.991 179.448 214.541 1.00 53.70  ? 284 THR N C   1 
ATOM   4598 O O   . THR D 4 281 ? 231.076 179.157 215.739 1.00 53.70  ? 284 THR N O   1 
ATOM   4599 C CB  . THR D 4 281 ? 233.295 178.511 214.358 1.00 53.70  ? 284 THR N CB  1 
ATOM   4600 O OG1 . THR D 4 281 ? 233.742 179.197 215.535 1.00 53.70  ? 284 THR N OG1 1 
ATOM   4601 C CG2 . THR D 4 281 ? 234.479 178.276 213.435 1.00 53.70  ? 284 THR N CG2 1 
ATOM   4602 N N   . ILE D 4 282 ? 229.866 179.904 213.986 1.00 47.16  ? 285 ILE N N   1 
ATOM   4603 C CA  . ILE D 4 282 ? 228.625 180.025 214.747 1.00 47.16  ? 285 ILE N CA  1 
ATOM   4604 C C   . ILE D 4 282 ? 228.350 178.709 215.457 1.00 47.16  ? 285 ILE N C   1 
ATOM   4605 O O   . ILE D 4 282 ? 228.144 177.673 214.817 1.00 47.16  ? 285 ILE N O   1 
ATOM   4606 C CB  . ILE D 4 282 ? 227.444 180.411 213.841 1.00 47.16  ? 285 ILE N CB  1 
ATOM   4607 C CG1 . ILE D 4 282 ? 227.730 181.723 213.116 1.00 47.16  ? 285 ILE N CG1 1 
ATOM   4608 C CG2 . ILE D 4 282 ? 226.166 180.508 214.651 1.00 47.16  ? 285 ILE N CG2 1 
ATOM   4609 C CD1 . ILE D 4 282 ? 226.550 182.264 212.350 1.00 47.16  ? 285 ILE N CD1 1 
ATOM   4610 N N   . THR D 4 283 ? 228.337 178.744 216.789 1.00 50.32  ? 286 THR N N   1 
ATOM   4611 C CA  . THR D 4 283 ? 228.262 177.516 217.568 1.00 50.32  ? 286 THR N CA  1 
ATOM   4612 C C   . THR D 4 283 ? 226.840 177.252 218.046 1.00 50.32  ? 286 THR N C   1 
ATOM   4613 O O   . THR D 4 283 ? 226.293 176.164 217.831 1.00 50.32  ? 286 THR N O   1 
ATOM   4614 C CB  . THR D 4 283 ? 229.222 177.594 218.757 1.00 50.32  ? 286 THR N CB  1 
ATOM   4615 O OG1 . THR D 4 283 ? 230.569 177.665 218.278 1.00 50.32  ? 286 THR N OG1 1 
ATOM   4616 C CG2 . THR D 4 283 ? 229.071 176.371 219.644 1.00 50.32  ? 286 THR N CG2 1 
ATOM   4617 N N   . ASP D 4 284 ? 226.230 178.232 218.696 1.00 49.11  ? 287 ASP N N   1 
ATOM   4618 C CA  . ASP D 4 284 ? 224.890 178.103 219.241 1.00 49.11  ? 287 ASP N CA  1 
ATOM   4619 C C   . ASP D 4 284 ? 223.990 179.177 218.635 1.00 49.11  ? 287 ASP N C   1 
ATOM   4620 O O   . ASP D 4 284 ? 224.451 180.223 218.173 1.00 49.11  ? 287 ASP N O   1 
ATOM   4621 C CB  . ASP D 4 284 ? 224.928 178.195 220.766 1.00 49.11  ? 287 ASP N CB  1 
ATOM   4622 C CG  . ASP D 4 284 ? 223.660 177.682 221.414 1.00 49.11  ? 287 ASP N CG  1 
ATOM   4623 O OD1 . ASP D 4 284 ? 222.742 177.259 220.679 1.00 49.11  ? 287 ASP N OD1 1 
ATOM   4624 O OD2 . ASP D 4 284 ? 223.579 177.703 222.659 1.00 49.11  ? 287 ASP N OD2 1 
ATOM   4625 N N   . ALA D 4 285 ? 222.690 178.905 218.644 1.00 47.61  ? 288 ALA N N   1 
ATOM   4626 C CA  . ALA D 4 285 ? 221.720 179.826 218.065 1.00 47.61  ? 288 ALA N CA  1 
ATOM   4627 C C   . ALA D 4 285 ? 220.499 179.879 218.969 1.00 47.61  ? 288 ALA N C   1 
ATOM   4628 O O   . ALA D 4 285 ? 220.206 178.939 219.710 1.00 47.61  ? 288 ALA N O   1 
ATOM   4629 C CB  . ALA D 4 285 ? 221.337 179.408 216.644 1.00 47.61  ? 288 ALA N CB  1 
ATOM   4630 N N   . VAL D 4 286 ? 219.788 181.002 218.898 1.00 47.99  ? 289 VAL N N   1 
ATOM   4631 C CA  . VAL D 4 286 ? 218.611 181.220 219.731 1.00 47.99  ? 289 VAL N CA  1 
ATOM   4632 C C   . VAL D 4 286 ? 217.480 181.795 218.890 1.00 47.99  ? 289 VAL N C   1 
ATOM   4633 O O   . VAL D 4 286 ? 217.630 182.849 218.261 1.00 47.99  ? 289 VAL N O   1 
ATOM   4634 C CB  . VAL D 4 286 ? 218.940 182.136 220.924 1.00 47.99  ? 289 VAL N CB  1 
ATOM   4635 C CG1 . VAL D 4 286 ? 217.681 182.746 221.496 1.00 47.99  ? 289 VAL N CG1 1 
ATOM   4636 C CG2 . VAL D 4 286 ? 219.655 181.351 222.003 1.00 47.99  ? 289 VAL N CG2 1 
ATOM   4637 N N   . ASP D 4 287 ? 216.347 181.101 218.865 1.00 57.83  ? 290 ASP N N   1 
ATOM   4638 C CA  . ASP D 4 287 ? 215.152 181.630 218.226 1.00 57.83  ? 290 ASP N CA  1 
ATOM   4639 C C   . ASP D 4 287 ? 214.606 182.787 219.050 1.00 57.83  ? 290 ASP N C   1 
ATOM   4640 O O   . ASP D 4 287 ? 214.897 182.901 220.241 1.00 57.83  ? 290 ASP N O   1 
ATOM   4641 C CB  . ASP D 4 287 ? 214.099 180.534 218.097 1.00 57.83  ? 290 ASP N CB  1 
ATOM   4642 C CG  . ASP D 4 287 ? 214.304 179.669 216.876 1.00 57.83  ? 290 ASP N CG  1 
ATOM   4643 O OD1 . ASP D 4 287 ? 215.078 180.073 215.990 1.00 57.83  ? 290 ASP N OD1 1 
ATOM   4644 O OD2 . ASP D 4 287 ? 213.679 178.590 216.799 1.00 57.83  ? 290 ASP N OD2 1 
HETATM 4645 C C1  . NAG E 5 .   ? 216.886 183.843 177.057 1.00 30.00  ? 1   NAG A C1  1 
HETATM 4646 C C2  . NAG E 5 .   ? 216.139 184.587 175.966 1.00 30.00  ? 1   NAG A C2  1 
HETATM 4647 C C3  . NAG E 5 .   ? 216.089 186.054 176.347 1.00 30.00  ? 1   NAG A C3  1 
HETATM 4648 C C4  . NAG E 5 .   ? 215.637 186.280 177.792 1.00 30.00  ? 1   NAG A C4  1 
HETATM 4649 C C5  . NAG E 5 .   ? 215.994 185.165 178.783 1.00 30.00  ? 1   NAG A C5  1 
HETATM 4650 C C6  . NAG E 5 .   ? 214.974 185.091 179.913 1.00 30.00  ? 1   NAG A C6  1 
HETATM 4651 C C7  . NAG E 5 .   ? 216.108 183.963 173.629 1.00 30.00  ? 1   NAG A C7  1 
HETATM 4652 C C8  . NAG E 5 .   ? 216.599 182.670 173.049 1.00 30.00  ? 1   NAG A C8  1 
HETATM 4653 N N2  . NAG E 5 .   ? 216.781 184.423 174.677 1.00 30.00  ? 1   NAG A N2  1 
HETATM 4654 O O3  . NAG E 5 .   ? 215.185 186.722 175.458 1.00 30.00  ? 1   NAG A O3  1 
HETATM 4655 O O4  . NAG E 5 .   ? 216.273 187.479 178.243 1.00 30.00  ? 1   NAG A O4  1 
HETATM 4656 O O5  . NAG E 5 .   ? 216.034 183.872 178.186 1.00 30.00  ? 1   NAG A O5  1 
HETATM 4657 O O6  . NAG E 5 .   ? 215.661 184.958 181.161 1.00 30.00  ? 1   NAG A O6  1 
HETATM 4658 O O7  . NAG E 5 .   ? 215.149 184.558 173.165 1.00 30.00  ? 1   NAG A O7  1 
HETATM 4659 C C1  . NAG E 5 .   ? 215.327 188.552 178.394 1.00 30.00  ? 2   NAG A C1  1 
HETATM 4660 C C2  . NAG E 5 .   ? 215.964 189.595 179.309 1.00 30.00  ? 2   NAG A C2  1 
HETATM 4661 C C3  . NAG E 5 .   ? 215.904 191.006 178.726 1.00 30.00  ? 2   NAG A C3  1 
HETATM 4662 C C4  . NAG E 5 .   ? 214.550 191.317 178.092 1.00 30.00  ? 2   NAG A C4  1 
HETATM 4663 C C5  . NAG E 5 .   ? 213.990 190.146 177.286 1.00 30.00  ? 2   NAG A C5  1 
HETATM 4664 C C6  . NAG E 5 .   ? 213.544 190.578 175.894 1.00 30.00  ? 2   NAG A C6  1 
HETATM 4665 C C7  . NAG E 5 .   ? 215.641 188.695 181.539 1.00 30.00  ? 2   NAG A C7  1 
HETATM 4666 C C8  . NAG E 5 .   ? 217.081 188.671 181.962 1.00 30.00  ? 2   NAG A C8  1 
HETATM 4667 N N2  . NAG E 5 .   ? 215.315 189.582 180.606 1.00 30.00  ? 2   NAG A N2  1 
HETATM 4668 O O3  . NAG E 5 .   ? 216.929 191.161 177.738 1.00 30.00  ? 2   NAG A O3  1 
HETATM 4669 O O4  . NAG E 5 .   ? 213.622 191.680 179.127 1.00 30.00  ? 2   NAG A O4  1 
HETATM 4670 O O5  . NAG E 5 .   ? 214.982 189.139 177.144 1.00 30.00  ? 2   NAG A O5  1 
HETATM 4671 O O6  . NAG E 5 .   ? 214.537 191.412 175.286 1.00 30.00  ? 2   NAG A O6  1 
HETATM 4672 O O7  . NAG E 5 .   ? 214.815 187.946 182.028 1.00 30.00  ? 2   NAG A O7  1 
HETATM 4673 C C1  . BMA E 5 .   ? 213.112 193.025 178.971 1.00 30.00  ? 3   BMA A C1  1 
HETATM 4674 C C2  . BMA E 5 .   ? 213.509 193.928 180.136 1.00 30.00  ? 3   BMA A C2  1 
HETATM 4675 C C3  . BMA E 5 .   ? 212.783 195.271 180.023 1.00 30.00  ? 3   BMA A C3  1 
HETATM 4676 C C4  . BMA E 5 .   ? 212.899 195.854 178.616 1.00 30.00  ? 3   BMA A C4  1 
HETATM 4677 C C5  . BMA E 5 .   ? 212.530 194.817 177.563 1.00 30.00  ? 3   BMA A C5  1 
HETATM 4678 C C6  . BMA E 5 .   ? 212.712 195.360 176.153 1.00 30.00  ? 3   BMA A C6  1 
HETATM 4679 O O2  . BMA E 5 .   ? 214.933 194.121 180.167 1.00 30.00  ? 3   BMA A O2  1 
HETATM 4680 O O3  . BMA E 5 .   ? 213.311 196.208 180.975 1.00 30.00  ? 3   BMA A O3  1 
HETATM 4681 O O4  . BMA E 5 .   ? 212.029 196.985 178.498 1.00 30.00  ? 3   BMA A O4  1 
HETATM 4682 O O5  . BMA E 5 .   ? 213.361 193.676 177.725 1.00 30.00  ? 3   BMA A O5  1 
HETATM 4683 O O6  . BMA E 5 .   ? 211.439 195.768 175.642 1.00 30.00  ? 3   BMA A O6  1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    GLU 1    1    1   GLU GLU L . n 
A 1 2    ILE 2    2    2   ILE ILE L . n 
A 1 3    VAL 3    3    3   VAL VAL L . n 
A 1 4    MET 4    4    4   MET MET L . n 
A 1 5    THR 5    5    5   THR THR L . n 
A 1 6    GLN 6    6    6   GLN GLN L . n 
A 1 7    SER 7    7    7   SER SER L . n 
A 1 8    PRO 8    8    8   PRO PRO L . n 
A 1 9    ALA 9    9    9   ALA ALA L . n 
A 1 10   THR 10   10   10  THR THR L . n 
A 1 11   LEU 11   11   11  LEU LEU L . n 
A 1 12   SER 12   12   12  SER SER L . n 
A 1 13   VAL 13   13   13  VAL VAL L . n 
A 1 14   SER 14   14   14  SER SER L . n 
A 1 15   PRO 15   15   15  PRO PRO L . n 
A 1 16   GLY 16   16   16  GLY GLY L . n 
A 1 17   GLU 17   17   17  GLU GLU L . n 
A 1 18   ARG 18   18   18  ARG ARG L . n 
A 1 19   ALA 19   19   19  ALA ALA L . n 
A 1 20   THR 20   20   20  THR THR L . n 
A 1 21   LEU 21   21   21  LEU LEU L . n 
A 1 22   SER 22   22   22  SER SER L . n 
A 1 23   CYS 23   23   23  CYS CYS L . n 
A 1 24   ARG 24   24   24  ARG ARG L . n 
A 1 25   ALA 25   25   25  ALA ALA L . n 
A 1 26   SER 26   26   26  SER SER L . n 
A 1 27   GLN 27   27   27  GLN GLN L . n 
A 1 28   SER 28   28   28  SER SER L . n 
A 1 29   VAL 29   29   29  VAL VAL L . n 
A 1 30   SER 30   30   30  SER SER L . n 
A 1 31   ARG 31   31   31  ARG ARG L . n 
A 1 32   ASN 32   32   32  ASN ASN L . n 
A 1 33   LEU 33   33   33  LEU LEU L . n 
A 1 34   ALA 34   34   34  ALA ALA L . n 
A 1 35   TRP 35   35   35  TRP TRP L . n 
A 1 36   TYR 36   36   36  TYR TYR L . n 
A 1 37   GLN 37   37   37  GLN GLN L . n 
A 1 38   GLN 38   38   38  GLN GLN L . n 
A 1 39   ARG 39   39   39  ARG ARG L . n 
A 1 40   PRO 40   40   40  PRO PRO L . n 
A 1 41   GLY 41   41   41  GLY GLY L . n 
A 1 42   GLN 42   42   42  GLN GLN L . n 
A 1 43   ALA 43   43   43  ALA ALA L . n 
A 1 44   PRO 44   44   44  PRO PRO L . n 
A 1 45   ARG 45   45   45  ARG ARG L . n 
A 1 46   LEU 46   46   46  LEU LEU L . n 
A 1 47   LEU 47   47   47  LEU LEU L . n 
A 1 48   ILE 48   48   48  ILE ILE L . n 
A 1 49   TYR 49   49   49  TYR TYR L . n 
A 1 50   GLY 50   50   50  GLY GLY L . n 
A 1 51   ALA 51   51   51  ALA ALA L . n 
A 1 52   SER 52   52   52  SER SER L . n 
A 1 53   THR 53   53   53  THR THR L . n 
A 1 54   ARG 54   54   54  ARG ARG L . n 
A 1 55   ALA 55   55   55  ALA ALA L . n 
A 1 56   THR 56   56   56  THR THR L . n 
A 1 57   GLY 57   57   57  GLY GLY L . n 
A 1 58   VAL 58   58   58  VAL VAL L . n 
A 1 59   ALA 59   59   59  ALA ALA L . n 
A 1 60   ALA 60   60   60  ALA ALA L . n 
A 1 61   ARG 61   61   61  ARG ARG L . n 
A 1 62   PHE 62   62   62  PHE PHE L . n 
A 1 63   THR 63   63   63  THR THR L . n 
A 1 64   GLY 64   64   64  GLY GLY L . n 
A 1 65   SER 65   65   65  SER SER L . n 
A 1 66   GLY 66   66   66  GLY GLY L . n 
A 1 67   PHE 67   67   67  PHE PHE L . n 
A 1 68   GLY 68   68   68  GLY GLY L . n 
A 1 69   THR 69   69   69  THR THR L . n 
A 1 70   GLU 70   70   70  GLU GLU L . n 
A 1 71   PHE 71   71   71  PHE PHE L . n 
A 1 72   THR 72   72   72  THR THR L . n 
A 1 73   LEU 73   73   73  LEU LEU L . n 
A 1 74   THR 74   74   74  THR THR L . n 
A 1 75   ILE 75   75   75  ILE ILE L . n 
A 1 76   SER 76   76   76  SER SER L . n 
A 1 77   GLY 77   77   77  GLY GLY L . n 
A 1 78   LEU 78   78   78  LEU LEU L . n 
A 1 79   GLN 79   79   79  GLN GLN L . n 
A 1 80   SER 80   80   80  SER SER L . n 
A 1 81   GLU 81   81   81  GLU GLU L . n 
A 1 82   ASP 82   82   82  ASP ASP L . n 
A 1 83   PHE 83   83   83  PHE PHE L . n 
A 1 84   ALA 84   84   84  ALA ALA L . n 
A 1 85   VAL 85   85   85  VAL VAL L . n 
A 1 86   TYR 86   86   86  TYR TYR L . n 
A 1 87   TYR 87   87   87  TYR TYR L . n 
A 1 88   CYS 88   88   88  CYS CYS L . n 
A 1 89   GLN 89   89   89  GLN GLN L . n 
A 1 90   GLU 90   90   90  GLU GLU L . n 
A 1 91   TYR 91   91   91  TYR TYR L . n 
A 1 92   ASN 92   92   92  ASN ASN L . n 
A 1 93   ASN 93   93   93  ASN ASN L . n 
A 1 94   TRP 94   94   94  TRP TRP L . n 
A 1 95   PRO 95   95   95  PRO PRO L . n 
A 1 96   PRO 96   96   96  PRO PRO L . n 
A 1 97   TRP 97   97   97  TRP TRP L . n 
A 1 98   THR 98   98   98  THR THR L . n 
A 1 99   PHE 99   99   99  PHE PHE L . n 
A 1 100  GLY 100  100  100 GLY GLY L . n 
A 1 101  GLN 101  101  101 GLN GLN L . n 
A 1 102  GLY 102  102  102 GLY GLY L . n 
A 1 103  THR 103  103  103 THR THR L . n 
A 1 104  LYS 104  104  104 LYS LYS L . n 
A 1 105  VAL 105  105  105 VAL VAL L . n 
A 1 106  GLU 106  106  106 GLU GLU L . n 
A 1 107  ILE 107  107  107 ILE ILE L . n 
A 1 108  LYS 108  108  108 LYS LYS L . n 
A 1 109  ARG 109  109  ?   ?   ?   L . n 
A 1 110  THR 110  110  ?   ?   ?   L . n 
A 1 111  VAL 111  111  ?   ?   ?   L . n 
A 1 112  ALA 112  112  ?   ?   ?   L . n 
A 1 113  ALA 113  113  ?   ?   ?   L . n 
A 1 114  PRO 114  114  ?   ?   ?   L . n 
A 1 115  SER 115  115  ?   ?   ?   L . n 
A 1 116  VAL 116  116  ?   ?   ?   L . n 
A 1 117  PHE 117  117  ?   ?   ?   L . n 
A 1 118  ILE 118  118  ?   ?   ?   L . n 
A 1 119  PHE 119  119  ?   ?   ?   L . n 
A 1 120  PRO 120  120  ?   ?   ?   L . n 
A 1 121  PRO 121  121  ?   ?   ?   L . n 
A 1 122  SER 122  122  ?   ?   ?   L . n 
A 1 123  ASP 123  123  ?   ?   ?   L . n 
A 1 124  GLU 124  124  ?   ?   ?   L . n 
A 1 125  GLN 125  125  ?   ?   ?   L . n 
A 1 126  LEU 126  126  ?   ?   ?   L . n 
A 1 127  LYS 127  127  ?   ?   ?   L . n 
A 1 128  SER 128  128  ?   ?   ?   L . n 
A 1 129  GLY 129  129  ?   ?   ?   L . n 
A 1 130  THR 130  130  ?   ?   ?   L . n 
A 1 131  ALA 131  131  ?   ?   ?   L . n 
A 1 132  SER 132  132  ?   ?   ?   L . n 
A 1 133  VAL 133  133  ?   ?   ?   L . n 
A 1 134  VAL 134  134  ?   ?   ?   L . n 
A 1 135  CYS 135  135  ?   ?   ?   L . n 
A 1 136  LEU 136  136  ?   ?   ?   L . n 
A 1 137  LEU 137  137  ?   ?   ?   L . n 
A 1 138  ASN 138  138  ?   ?   ?   L . n 
A 1 139  ASN 139  139  ?   ?   ?   L . n 
A 1 140  PHE 140  140  ?   ?   ?   L . n 
A 1 141  TYR 141  141  ?   ?   ?   L . n 
A 1 142  PRO 142  142  ?   ?   ?   L . n 
A 1 143  ARG 143  143  ?   ?   ?   L . n 
A 1 144  GLU 144  144  ?   ?   ?   L . n 
A 1 145  ALA 145  145  ?   ?   ?   L . n 
A 1 146  LYS 146  146  ?   ?   ?   L . n 
A 1 147  VAL 147  147  ?   ?   ?   L . n 
A 1 148  GLN 148  148  ?   ?   ?   L . n 
A 1 149  TRP 149  149  ?   ?   ?   L . n 
A 1 150  LYS 150  150  ?   ?   ?   L . n 
A 1 151  VAL 151  151  ?   ?   ?   L . n 
A 1 152  ASP 152  152  ?   ?   ?   L . n 
A 1 153  ASN 153  153  ?   ?   ?   L . n 
A 1 154  ALA 154  154  ?   ?   ?   L . n 
A 1 155  LEU 155  155  ?   ?   ?   L . n 
A 1 156  GLN 156  156  ?   ?   ?   L . n 
A 1 157  SER 157  157  ?   ?   ?   L . n 
A 1 158  GLY 158  158  ?   ?   ?   L . n 
A 1 159  ASN 159  159  ?   ?   ?   L . n 
A 1 160  SER 160  160  ?   ?   ?   L . n 
A 1 161  GLN 161  161  ?   ?   ?   L . n 
A 1 162  GLU 162  162  ?   ?   ?   L . n 
A 1 163  SER 163  163  ?   ?   ?   L . n 
A 1 164  VAL 164  164  ?   ?   ?   L . n 
A 1 165  THR 165  165  ?   ?   ?   L . n 
A 1 166  GLU 166  166  ?   ?   ?   L . n 
A 1 167  GLN 167  167  ?   ?   ?   L . n 
A 1 168  ASP 168  168  ?   ?   ?   L . n 
A 1 169  SER 169  169  ?   ?   ?   L . n 
A 1 170  LYS 170  170  ?   ?   ?   L . n 
A 1 171  ASP 171  171  ?   ?   ?   L . n 
A 1 172  SER 172  172  ?   ?   ?   L . n 
A 1 173  THR 173  173  ?   ?   ?   L . n 
A 1 174  TYR 174  174  ?   ?   ?   L . n 
A 1 175  SER 175  175  ?   ?   ?   L . n 
A 1 176  LEU 176  176  ?   ?   ?   L . n 
A 1 177  SER 177  177  ?   ?   ?   L . n 
A 1 178  SER 178  178  ?   ?   ?   L . n 
A 1 179  THR 179  179  ?   ?   ?   L . n 
A 1 180  LEU 180  180  ?   ?   ?   L . n 
A 1 181  THR 181  181  ?   ?   ?   L . n 
A 1 182  LEU 182  182  ?   ?   ?   L . n 
A 1 183  SER 183  183  ?   ?   ?   L . n 
A 1 184  LYS 184  184  ?   ?   ?   L . n 
A 1 185  ALA 185  185  ?   ?   ?   L . n 
A 1 186  ASP 186  186  ?   ?   ?   L . n 
A 1 187  TYR 187  187  ?   ?   ?   L . n 
A 1 188  GLU 188  188  ?   ?   ?   L . n 
A 1 189  LYS 189  189  ?   ?   ?   L . n 
A 1 190  HIS 190  190  ?   ?   ?   L . n 
A 1 191  LYS 191  191  ?   ?   ?   L . n 
A 1 192  VAL 192  192  ?   ?   ?   L . n 
A 1 193  TYR 193  193  ?   ?   ?   L . n 
A 1 194  ALA 194  194  ?   ?   ?   L . n 
A 1 195  CYS 195  195  ?   ?   ?   L . n 
A 1 196  GLU 196  196  ?   ?   ?   L . n 
A 1 197  VAL 197  197  ?   ?   ?   L . n 
A 1 198  THR 198  198  ?   ?   ?   L . n 
A 1 199  HIS 199  199  ?   ?   ?   L . n 
A 1 200  GLN 200  200  ?   ?   ?   L . n 
A 1 201  GLY 201  201  ?   ?   ?   L . n 
A 1 202  LEU 202  202  ?   ?   ?   L . n 
A 1 203  SER 203  203  ?   ?   ?   L . n 
A 1 204  SER 204  204  ?   ?   ?   L . n 
A 1 205  PRO 205  205  ?   ?   ?   L . n 
A 1 206  VAL 206  206  ?   ?   ?   L . n 
A 1 207  THR 207  207  ?   ?   ?   L . n 
A 1 208  LYS 208  208  ?   ?   ?   L . n 
A 1 209  SER 209  209  ?   ?   ?   L . n 
A 1 210  PHE 210  210  ?   ?   ?   L . n 
A 1 211  ASN 211  211  ?   ?   ?   L . n 
A 1 212  ARG 212  212  ?   ?   ?   L . n 
A 1 213  GLY 213  213  ?   ?   ?   L . n 
A 1 214  GLU 214  214  ?   ?   ?   L . n 
A 1 215  CYS 215  215  ?   ?   ?   L . n 
B 2 1    GLN 1    1    ?   ?   ?   H . n 
B 2 2    VAL 2    2    2   VAL VAL H . n 
B 2 3    GLN 3    3    3   GLN GLN H . n 
B 2 4    LEU 4    4    4   LEU LEU H . n 
B 2 5    VAL 5    5    5   VAL VAL H . n 
B 2 6    GLU 6    6    6   GLU GLU H . n 
B 2 7    SER 7    7    7   SER SER H . n 
B 2 8    GLY 8    8    8   GLY GLY H . n 
B 2 9    GLY 9    9    9   GLY GLY H . n 
B 2 10   GLY 10   10   10  GLY GLY H . n 
B 2 11   LEU 11   11   11  LEU LEU H . n 
B 2 12   VAL 12   12   12  VAL VAL H . n 
B 2 13   LYS 13   13   13  LYS LYS H . n 
B 2 14   PRO 14   14   14  PRO PRO H . n 
B 2 15   GLY 15   15   15  GLY GLY H . n 
B 2 16   GLY 16   16   16  GLY GLY H . n 
B 2 17   SER 17   17   17  SER SER H . n 
B 2 18   LEU 18   18   18  LEU LEU H . n 
B 2 19   ARG 19   19   19  ARG ARG H . n 
B 2 20   LEU 20   20   20  LEU LEU H . n 
B 2 21   SER 21   21   21  SER SER H . n 
B 2 22   CYS 22   22   22  CYS CYS H . n 
B 2 23   ALA 23   23   23  ALA ALA H . n 
B 2 24   ALA 24   24   24  ALA ALA H . n 
B 2 25   SER 25   25   25  SER SER H . n 
B 2 26   GLY 26   26   26  GLY GLY H . n 
B 2 27   PHE 27   27   27  PHE PHE H . n 
B 2 28   ARG 28   28   28  ARG ARG H . n 
B 2 29   PHE 29   29   29  PHE PHE H . n 
B 2 30   SER 30   30   30  SER SER H . n 
B 2 31   ASP 31   31   31  ASP ASP H . n 
B 2 32   TYR 32   32   32  TYR TYR H . n 
B 2 33   TYR 33   33   33  TYR TYR H . n 
B 2 34   MET 34   34   34  MET MET H . n 
B 2 35   ASN 35   35   35  ASN ASN H . n 
B 2 36   TRP 36   36   36  TRP TRP H . n 
B 2 37   ILE 37   37   37  ILE ILE H . n 
B 2 38   ARG 38   38   38  ARG ARG H . n 
B 2 39   GLN 39   39   39  GLN GLN H . n 
B 2 40   ALA 40   40   40  ALA ALA H . n 
B 2 41   PRO 41   41   41  PRO PRO H . n 
B 2 42   GLY 42   42   42  GLY GLY H . n 
B 2 43   LYS 43   43   43  LYS LYS H . n 
B 2 44   GLY 44   44   44  GLY GLY H . n 
B 2 45   LEU 45   45   45  LEU LEU H . n 
B 2 46   GLU 46   46   46  GLU GLU H . n 
B 2 47   TRP 47   47   47  TRP TRP H . n 
B 2 48   ILE 48   48   48  ILE ILE H . n 
B 2 49   SER 49   49   49  SER SER H . n 
B 2 50   TYR 50   50   50  TYR TYR H . n 
B 2 51   ILE 51   51   51  ILE ILE H . n 
B 2 52   GLY 52   52   52  GLY GLY H . n 
B 2 53   SER 53   53   53  SER SER H . n 
B 2 54   GLY 54   54   54  GLY GLY H . n 
B 2 55   GLY 55   55   55  GLY GLY H . n 
B 2 56   PHE 56   56   56  PHE PHE H . n 
B 2 57   ALA 57   57   57  ALA ALA H . n 
B 2 58   THR 58   58   58  THR THR H . n 
B 2 59   TYR 59   59   59  TYR TYR H . n 
B 2 60   TYR 60   60   60  TYR TYR H . n 
B 2 61   GLY 61   61   61  GLY GLY H . n 
B 2 62   ASP 62   62   62  ASP ASP H . n 
B 2 63   SER 63   63   63  SER SER H . n 
B 2 64   VAL 64   64   64  VAL VAL H . n 
B 2 65   LYS 65   65   65  LYS LYS H . n 
B 2 66   GLY 66   66   66  GLY GLY H . n 
B 2 67   ARG 67   67   67  ARG ARG H . n 
B 2 68   PHE 68   68   68  PHE PHE H . n 
B 2 69   THR 69   69   69  THR THR H . n 
B 2 70   VAL 70   70   70  VAL VAL H . n 
B 2 71   SER 71   71   71  SER SER H . n 
B 2 72   ARG 72   72   72  ARG ARG H . n 
B 2 73   ASP 73   73   73  ASP ASP H . n 
B 2 74   ASP 74   74   74  ASP ASP H . n 
B 2 75   ALA 75   75   75  ALA ALA H . n 
B 2 76   GLU 76   76   76  GLU GLU H . n 
B 2 77   ASN 77   77   77  ASN ASN H . n 
B 2 78   SER 78   78   78  SER SER H . n 
B 2 79   LEU 79   79   79  LEU LEU H . n 
B 2 80   TYR 80   80   80  TYR TYR H . n 
B 2 81   LEU 81   81   81  LEU LEU H . n 
B 2 82   GLN 82   82   82  GLN GLN H . n 
B 2 83   MET 83   83   83  MET MET H . n 
B 2 84   ASN 84   84   84  ASN ASN H . n 
B 2 85   SER 85   85   85  SER SER H . n 
B 2 86   LEU 86   86   86  LEU LEU H . n 
B 2 87   ARG 87   87   87  ARG ARG H . n 
B 2 88   ALA 88   88   88  ALA ALA H . n 
B 2 89   GLU 89   89   89  GLU GLU H . n 
B 2 90   ASP 90   90   90  ASP ASP H . n 
B 2 91   THR 91   91   91  THR THR H . n 
B 2 92   ALA 92   92   92  ALA ALA H . n 
B 2 93   VAL 93   93   93  VAL VAL H . n 
B 2 94   TYR 94   94   94  TYR TYR H . n 
B 2 95   TYR 95   95   95  TYR TYR H . n 
B 2 96   CYS 96   96   96  CYS CYS H . n 
B 2 97   ALA 97   97   97  ALA ALA H . n 
B 2 98   ARG 98   98   98  ARG ARG H . n 
B 2 99   GLY 99   99   99  GLY GLY H . n 
B 2 100  VAL 100  100  100 VAL VAL H . n 
B 2 101  THR 101  101  101 THR THR H . n 
B 2 102  SER 102  102  102 SER SER H . n 
B 2 103  TYR 103  103  103 TYR TYR H . n 
B 2 104  SER 104  104  104 SER SER H . n 
B 2 105  ASP 105  105  105 ASP ASP H . n 
B 2 106  ASN 106  106  106 ASN ALA H . n 
B 2 107  SER 107  107  107 SER SER H . n 
B 2 108  GLY 108  108  108 GLY GLY H . n 
B 2 109  ASN 109  109  109 ASN ASN H . n 
B 2 110  TYR 110  110  110 TYR TYR H . n 
B 2 111  ARG 111  111  111 ARG ARG H . n 
B 2 112  THR 112  112  112 THR THR H . n 
B 2 113  ASP 113  113  113 ASP ASP H . n 
B 2 114  ASP 114  114  114 ASP ASP H . n 
B 2 115  ALA 115  115  115 ALA ALA H . n 
B 2 116  PHE 116  116  116 PHE PHE H . n 
B 2 117  ASP 117  117  117 ASP ASP H . n 
B 2 118  ILE 118  118  118 ILE ILE H . n 
B 2 119  TRP 119  119  119 TRP TRP H . n 
B 2 120  GLY 120  120  120 GLY GLY H . n 
B 2 121  GLN 121  121  121 GLN GLN H . n 
B 2 122  GLY 122  122  122 GLY GLY H . n 
B 2 123  THR 123  123  123 THR THR H . n 
B 2 124  MET 124  124  124 MET MET H . n 
B 2 125  VAL 125  125  125 VAL VAL H . n 
B 2 126  THR 126  126  126 THR THR H . n 
B 2 127  VAL 127  127  127 VAL VAL H . n 
B 2 128  SER 128  128  128 SER SER H . n 
B 2 129  SER 129  129  129 SER SER H . n 
B 2 130  ALA 130  130  130 ALA ALA H . n 
B 2 131  SER 131  131  ?   ?   ?   H . n 
B 2 132  THR 132  132  ?   ?   ?   H . n 
B 2 133  LYS 133  133  ?   ?   ?   H . n 
B 2 134  GLY 134  134  ?   ?   ?   H . n 
B 2 135  PRO 135  135  ?   ?   ?   H . n 
B 2 136  SER 136  136  ?   ?   ?   H . n 
B 2 137  VAL 137  137  ?   ?   ?   H . n 
B 2 138  PHE 138  138  ?   ?   ?   H . n 
B 2 139  PRO 139  139  ?   ?   ?   H . n 
B 2 140  LEU 140  140  ?   ?   ?   H . n 
B 2 141  ALA 141  141  ?   ?   ?   H . n 
B 2 142  PRO 142  142  ?   ?   ?   H . n 
B 2 143  SER 143  143  ?   ?   ?   H . n 
B 2 144  SER 144  144  ?   ?   ?   H . n 
B 2 145  LYS 145  145  ?   ?   ?   H . n 
B 2 146  SER 146  146  ?   ?   ?   H . n 
B 2 147  THR 147  147  ?   ?   ?   H . n 
B 2 148  SER 148  148  ?   ?   ?   H . n 
B 2 149  GLY 149  149  ?   ?   ?   H . n 
B 2 150  GLY 150  150  ?   ?   ?   H . n 
B 2 151  THR 151  151  ?   ?   ?   H . n 
B 2 152  ALA 152  152  ?   ?   ?   H . n 
B 2 153  ALA 153  153  ?   ?   ?   H . n 
B 2 154  LEU 154  154  ?   ?   ?   H . n 
B 2 155  GLY 155  155  ?   ?   ?   H . n 
B 2 156  CYS 156  156  ?   ?   ?   H . n 
B 2 157  LEU 157  157  ?   ?   ?   H . n 
B 2 158  VAL 158  158  ?   ?   ?   H . n 
B 2 159  LYS 159  159  ?   ?   ?   H . n 
B 2 160  ASP 160  160  ?   ?   ?   H . n 
B 2 161  TYR 161  161  ?   ?   ?   H . n 
B 2 162  PHE 162  162  ?   ?   ?   H . n 
B 2 163  PRO 163  163  ?   ?   ?   H . n 
B 2 164  GLU 164  164  ?   ?   ?   H . n 
B 2 165  PRO 165  165  ?   ?   ?   H . n 
B 2 166  VAL 166  166  ?   ?   ?   H . n 
B 2 167  THR 167  167  ?   ?   ?   H . n 
B 2 168  VAL 168  168  ?   ?   ?   H . n 
B 2 169  SER 169  169  ?   ?   ?   H . n 
B 2 170  TRP 170  170  ?   ?   ?   H . n 
B 2 171  ASN 171  171  ?   ?   ?   H . n 
B 2 172  SER 172  172  ?   ?   ?   H . n 
B 2 173  GLY 173  173  ?   ?   ?   H . n 
B 2 174  ALA 174  174  ?   ?   ?   H . n 
B 2 175  LEU 175  175  ?   ?   ?   H . n 
B 2 176  THR 176  176  ?   ?   ?   H . n 
B 2 177  SER 177  177  ?   ?   ?   H . n 
B 2 178  GLY 178  178  ?   ?   ?   H . n 
B 2 179  VAL 179  179  ?   ?   ?   H . n 
B 2 180  HIS 180  180  ?   ?   ?   H . n 
B 2 181  THR 181  181  ?   ?   ?   H . n 
B 2 182  PHE 182  182  ?   ?   ?   H . n 
B 2 183  PRO 183  183  ?   ?   ?   H . n 
B 2 184  ALA 184  184  ?   ?   ?   H . n 
B 2 185  VAL 185  185  ?   ?   ?   H . n 
B 2 186  LEU 186  186  ?   ?   ?   H . n 
B 2 187  GLN 187  187  ?   ?   ?   H . n 
B 2 188  SER 188  188  ?   ?   ?   H . n 
B 2 189  SER 189  189  ?   ?   ?   H . n 
B 2 190  GLY 190  190  ?   ?   ?   H . n 
B 2 191  LEU 191  191  ?   ?   ?   H . n 
B 2 192  TYR 192  192  ?   ?   ?   H . n 
B 2 193  SER 193  193  ?   ?   ?   H . n 
B 2 194  LEU 194  194  ?   ?   ?   H . n 
B 2 195  SER 195  195  ?   ?   ?   H . n 
B 2 196  SER 196  196  ?   ?   ?   H . n 
B 2 197  VAL 197  197  ?   ?   ?   H . n 
B 2 198  VAL 198  198  ?   ?   ?   H . n 
B 2 199  THR 199  199  ?   ?   ?   H . n 
B 2 200  VAL 200  200  ?   ?   ?   H . n 
B 2 201  PRO 201  201  ?   ?   ?   H . n 
B 2 202  SER 202  202  ?   ?   ?   H . n 
B 2 203  SER 203  203  ?   ?   ?   H . n 
B 2 204  SER 204  204  ?   ?   ?   H . n 
B 2 205  LEU 205  205  ?   ?   ?   H . n 
B 2 206  GLY 206  206  ?   ?   ?   H . n 
B 2 207  THR 207  207  ?   ?   ?   H . n 
B 2 208  GLN 208  208  ?   ?   ?   H . n 
B 2 209  THR 209  209  ?   ?   ?   H . n 
B 2 210  TYR 210  210  ?   ?   ?   H . n 
B 2 211  ILE 211  211  ?   ?   ?   H . n 
B 2 212  CYS 212  212  ?   ?   ?   H . n 
B 2 213  ASN 213  213  ?   ?   ?   H . n 
B 2 214  VAL 214  214  ?   ?   ?   H . n 
B 2 215  ASN 215  215  ?   ?   ?   H . n 
B 2 216  HIS 216  216  ?   ?   ?   H . n 
B 2 217  LYS 217  217  ?   ?   ?   H . n 
B 2 218  PRO 218  218  ?   ?   ?   H . n 
B 2 219  SER 219  219  ?   ?   ?   H . n 
B 2 220  ASN 220  220  ?   ?   ?   H . n 
B 2 221  THR 221  221  ?   ?   ?   H . n 
B 2 222  LYS 222  222  ?   ?   ?   H . n 
B 2 223  VAL 223  223  ?   ?   ?   H . n 
B 2 224  ASP 224  224  ?   ?   ?   H . n 
B 2 225  LYS 225  225  ?   ?   ?   H . n 
B 2 226  LYS 226  226  ?   ?   ?   H . n 
B 2 227  VAL 227  227  ?   ?   ?   H . n 
B 2 228  GLU 228  228  ?   ?   ?   H . n 
B 2 229  PRO 229  229  ?   ?   ?   H . n 
B 2 230  LYS 230  230  ?   ?   ?   H . n 
B 2 231  SER 231  231  ?   ?   ?   H . n 
B 2 232  CYS 232  232  ?   ?   ?   H . n 
B 2 233  ASP 233  233  ?   ?   ?   H . n 
B 2 234  LYS 234  234  ?   ?   ?   H . n 
B 2 235  HIS 235  235  ?   ?   ?   H . n 
B 2 236  HIS 236  236  ?   ?   ?   H . n 
B 2 237  HIS 237  237  ?   ?   ?   H . n 
B 2 238  HIS 238  238  ?   ?   ?   H . n 
B 2 239  HIS 239  239  ?   ?   ?   H . n 
B 2 240  HIS 240  240  ?   ?   ?   H . n 
C 3 1    MET 1    4    ?   ?   ?   R . n 
C 3 2    PHE 2    5    ?   ?   ?   R . n 
C 3 3    VAL 3    6    ?   ?   ?   R . n 
C 3 4    PHE 4    7    ?   ?   ?   R . n 
C 3 5    LEU 5    8    ?   ?   ?   R . n 
C 3 6    VAL 6    9    ?   ?   ?   R . n 
C 3 7    LEU 7    10   ?   ?   ?   R . n 
C 3 8    LEU 8    11   ?   ?   ?   R . n 
C 3 9    PRO 9    12   ?   ?   ?   R . n 
C 3 10   LEU 10   13   ?   ?   ?   R . n 
C 3 11   VAL 11   14   ?   ?   ?   R . n 
C 3 12   SER 12   15   ?   ?   ?   R . n 
C 3 13   SER 13   16   ?   ?   ?   R . n 
C 3 14   GLN 14   17   ?   ?   ?   R . n 
C 3 15   CYS 15   18   ?   ?   ?   R . n 
C 3 16   VAL 16   19   ?   ?   ?   R . n 
C 3 17   ASN 17   20   ?   ?   ?   R . n 
C 3 18   PHE 18   21   ?   ?   ?   R . n 
C 3 19   THR 19   22   ?   ?   ?   R . n 
C 3 20   THR 20   23   ?   ?   ?   R . n 
C 3 21   ARG 21   24   ?   ?   ?   R . n 
C 3 22   THR 22   25   ?   ?   ?   R . n 
C 3 23   GLN 23   26   ?   ?   ?   R . n 
C 3 24   LEU 24   27   ?   ?   ?   R . n 
C 3 25   PRO 25   28   ?   ?   ?   R . n 
C 3 26   PRO 26   29   ?   ?   ?   R . n 
C 3 27   ALA 27   30   ?   ?   ?   R . n 
C 3 28   TYR 28   31   ?   ?   ?   R . n 
C 3 29   THR 29   32   ?   ?   ?   R . n 
C 3 30   ASN 30   33   ?   ?   ?   R . n 
C 3 31   SER 31   34   ?   ?   ?   R . n 
C 3 32   PHE 32   35   ?   ?   ?   R . n 
C 3 33   THR 33   36   ?   ?   ?   R . n 
C 3 34   ARG 34   37   ?   ?   ?   R . n 
C 3 35   GLY 35   38   ?   ?   ?   R . n 
C 3 36   VAL 36   39   ?   ?   ?   R . n 
C 3 37   TYR 37   40   ?   ?   ?   R . n 
C 3 38   TYR 38   41   ?   ?   ?   R . n 
C 3 39   PRO 39   42   ?   ?   ?   R . n 
C 3 40   ASP 40   43   ?   ?   ?   R . n 
C 3 41   LYS 41   44   ?   ?   ?   R . n 
C 3 42   VAL 42   45   ?   ?   ?   R . n 
C 3 43   PHE 43   46   ?   ?   ?   R . n 
C 3 44   ARG 44   47   ?   ?   ?   R . n 
C 3 45   SER 45   48   ?   ?   ?   R . n 
C 3 46   SER 46   49   ?   ?   ?   R . n 
C 3 47   VAL 47   50   ?   ?   ?   R . n 
C 3 48   LEU 48   51   ?   ?   ?   R . n 
C 3 49   HIS 49   52   ?   ?   ?   R . n 
C 3 50   SER 50   53   ?   ?   ?   R . n 
C 3 51   THR 51   54   ?   ?   ?   R . n 
C 3 52   GLN 52   55   ?   ?   ?   R . n 
C 3 53   ASP 53   56   ?   ?   ?   R . n 
C 3 54   LEU 54   57   ?   ?   ?   R . n 
C 3 55   PHE 55   58   ?   ?   ?   R . n 
C 3 56   LEU 56   59   ?   ?   ?   R . n 
C 3 57   PRO 57   60   ?   ?   ?   R . n 
C 3 58   PHE 58   61   ?   ?   ?   R . n 
C 3 59   PHE 59   62   ?   ?   ?   R . n 
C 3 60   SER 60   63   ?   ?   ?   R . n 
C 3 61   ASN 61   64   ?   ?   ?   R . n 
C 3 62   VAL 62   65   ?   ?   ?   R . n 
C 3 63   THR 63   66   ?   ?   ?   R . n 
C 3 64   TRP 64   67   ?   ?   ?   R . n 
C 3 65   PHE 65   68   ?   ?   ?   R . n 
C 3 66   HIS 66   69   ?   ?   ?   R . n 
C 3 67   ALA 67   70   ?   ?   ?   R . n 
C 3 68   ILE 68   71   ?   ?   ?   R . n 
C 3 69   HIS 69   72   ?   ?   ?   R . n 
C 3 70   VAL 70   73   ?   ?   ?   R . n 
C 3 71   SER 71   74   ?   ?   ?   R . n 
C 3 72   GLY 72   75   ?   ?   ?   R . n 
C 3 73   THR 73   76   ?   ?   ?   R . n 
C 3 74   ASN 74   77   ?   ?   ?   R . n 
C 3 75   GLY 75   78   ?   ?   ?   R . n 
C 3 76   THR 76   79   ?   ?   ?   R . n 
C 3 77   LYS 77   80   ?   ?   ?   R . n 
C 3 78   ARG 78   81   ?   ?   ?   R . n 
C 3 79   PHE 79   82   ?   ?   ?   R . n 
C 3 80   ALA 80   83   ?   ?   ?   R . n 
C 3 81   ASN 81   84   ?   ?   ?   R . n 
C 3 82   PRO 82   85   ?   ?   ?   R . n 
C 3 83   VAL 83   86   ?   ?   ?   R . n 
C 3 84   LEU 84   87   ?   ?   ?   R . n 
C 3 85   PRO 85   88   ?   ?   ?   R . n 
C 3 86   PHE 86   89   ?   ?   ?   R . n 
C 3 87   ASN 87   90   ?   ?   ?   R . n 
C 3 88   ASP 88   91   ?   ?   ?   R . n 
C 3 89   GLY 89   92   ?   ?   ?   R . n 
C 3 90   VAL 90   93   ?   ?   ?   R . n 
C 3 91   TYR 91   94   ?   ?   ?   R . n 
C 3 92   PHE 92   95   ?   ?   ?   R . n 
C 3 93   ALA 93   96   ?   ?   ?   R . n 
C 3 94   SER 94   97   ?   ?   ?   R . n 
C 3 95   THR 95   98   ?   ?   ?   R . n 
C 3 96   GLU 96   99   ?   ?   ?   R . n 
C 3 97   LYS 97   100  ?   ?   ?   R . n 
C 3 98   SER 98   101  ?   ?   ?   R . n 
C 3 99   ASN 99   102  ?   ?   ?   R . n 
C 3 100  ILE 100  103  ?   ?   ?   R . n 
C 3 101  ILE 101  104  ?   ?   ?   R . n 
C 3 102  ARG 102  105  ?   ?   ?   R . n 
C 3 103  GLY 103  106  ?   ?   ?   R . n 
C 3 104  TRP 104  107  ?   ?   ?   R . n 
C 3 105  ILE 105  108  ?   ?   ?   R . n 
C 3 106  PHE 106  109  ?   ?   ?   R . n 
C 3 107  GLY 107  110  ?   ?   ?   R . n 
C 3 108  THR 108  111  ?   ?   ?   R . n 
C 3 109  THR 109  112  ?   ?   ?   R . n 
C 3 110  LEU 110  113  ?   ?   ?   R . n 
C 3 111  ASP 111  114  ?   ?   ?   R . n 
C 3 112  SER 112  115  ?   ?   ?   R . n 
C 3 113  LYS 113  116  ?   ?   ?   R . n 
C 3 114  THR 114  117  ?   ?   ?   R . n 
C 3 115  GLN 115  118  ?   ?   ?   R . n 
C 3 116  SER 116  119  ?   ?   ?   R . n 
C 3 117  LEU 117  120  ?   ?   ?   R . n 
C 3 118  LEU 118  121  ?   ?   ?   R . n 
C 3 119  ILE 119  122  ?   ?   ?   R . n 
C 3 120  VAL 120  123  ?   ?   ?   R . n 
C 3 121  ASN 121  124  ?   ?   ?   R . n 
C 3 122  ASN 122  125  ?   ?   ?   R . n 
C 3 123  ALA 123  126  ?   ?   ?   R . n 
C 3 124  THR 124  127  ?   ?   ?   R . n 
C 3 125  ASN 125  128  ?   ?   ?   R . n 
C 3 126  VAL 126  129  ?   ?   ?   R . n 
C 3 127  VAL 127  130  ?   ?   ?   R . n 
C 3 128  ILE 128  131  ?   ?   ?   R . n 
C 3 129  LYS 129  132  ?   ?   ?   R . n 
C 3 130  VAL 130  133  ?   ?   ?   R . n 
C 3 131  CYS 131  134  ?   ?   ?   R . n 
C 3 132  GLU 132  135  ?   ?   ?   R . n 
C 3 133  PHE 133  136  ?   ?   ?   R . n 
C 3 134  GLN 134  137  ?   ?   ?   R . n 
C 3 135  PHE 135  138  ?   ?   ?   R . n 
C 3 136  CYS 136  139  ?   ?   ?   R . n 
C 3 137  ASN 137  140  ?   ?   ?   R . n 
C 3 138  ASP 138  141  ?   ?   ?   R . n 
C 3 139  PRO 139  142  ?   ?   ?   R . n 
C 3 140  PHE 140  143  ?   ?   ?   R . n 
C 3 141  LEU 141  144  ?   ?   ?   R . n 
C 3 142  GLY 142  145  ?   ?   ?   R . n 
C 3 143  VAL 143  146  ?   ?   ?   R . n 
C 3 144  TYR 144  147  ?   ?   ?   R . n 
C 3 145  TYR 145  148  ?   ?   ?   R . n 
C 3 146  HIS 146  149  ?   ?   ?   R . n 
C 3 147  LYS 147  150  ?   ?   ?   R . n 
C 3 148  ASN 148  151  ?   ?   ?   R . n 
C 3 149  ASN 149  152  ?   ?   ?   R . n 
C 3 150  LYS 150  153  ?   ?   ?   R . n 
C 3 151  SER 151  154  ?   ?   ?   R . n 
C 3 152  TRP 152  155  ?   ?   ?   R . n 
C 3 153  MET 153  156  ?   ?   ?   R . n 
C 3 154  GLU 154  157  ?   ?   ?   R . n 
C 3 155  SER 155  158  ?   ?   ?   R . n 
C 3 156  GLU 156  159  ?   ?   ?   R . n 
C 3 157  PHE 157  160  ?   ?   ?   R . n 
C 3 158  ARG 158  161  ?   ?   ?   R . n 
C 3 159  VAL 159  162  ?   ?   ?   R . n 
C 3 160  TYR 160  163  ?   ?   ?   R . n 
C 3 161  SER 161  164  ?   ?   ?   R . n 
C 3 162  SER 162  165  ?   ?   ?   R . n 
C 3 163  ALA 163  166  ?   ?   ?   R . n 
C 3 164  ASN 164  167  ?   ?   ?   R . n 
C 3 165  ASN 165  168  ?   ?   ?   R . n 
C 3 166  CYS 166  169  ?   ?   ?   R . n 
C 3 167  THR 167  170  ?   ?   ?   R . n 
C 3 168  PHE 168  171  ?   ?   ?   R . n 
C 3 169  GLU 169  172  ?   ?   ?   R . n 
C 3 170  TYR 170  173  ?   ?   ?   R . n 
C 3 171  VAL 171  174  ?   ?   ?   R . n 
C 3 172  SER 172  175  ?   ?   ?   R . n 
C 3 173  GLN 173  176  ?   ?   ?   R . n 
C 3 174  PRO 174  177  ?   ?   ?   R . n 
C 3 175  PHE 175  178  ?   ?   ?   R . n 
C 3 176  LEU 176  179  ?   ?   ?   R . n 
C 3 177  MET 177  180  ?   ?   ?   R . n 
C 3 178  ASP 178  181  ?   ?   ?   R . n 
C 3 179  LEU 179  182  ?   ?   ?   R . n 
C 3 180  GLU 180  183  ?   ?   ?   R . n 
C 3 181  GLY 181  184  ?   ?   ?   R . n 
C 3 182  LYS 182  185  ?   ?   ?   R . n 
C 3 183  GLN 183  186  ?   ?   ?   R . n 
C 3 184  GLY 184  187  ?   ?   ?   R . n 
C 3 185  ASN 185  188  ?   ?   ?   R . n 
C 3 186  PHE 186  189  ?   ?   ?   R . n 
C 3 187  LYS 187  190  ?   ?   ?   R . n 
C 3 188  ASN 188  191  ?   ?   ?   R . n 
C 3 189  LEU 189  192  ?   ?   ?   R . n 
C 3 190  ARG 190  193  ?   ?   ?   R . n 
C 3 191  GLU 191  194  ?   ?   ?   R . n 
C 3 192  PHE 192  195  ?   ?   ?   R . n 
C 3 193  VAL 193  196  ?   ?   ?   R . n 
C 3 194  PHE 194  197  ?   ?   ?   R . n 
C 3 195  LYS 195  198  ?   ?   ?   R . n 
C 3 196  ASN 196  199  ?   ?   ?   R . n 
C 3 197  ILE 197  200  ?   ?   ?   R . n 
C 3 198  ASP 198  201  ?   ?   ?   R . n 
C 3 199  GLY 199  202  ?   ?   ?   R . n 
C 3 200  TYR 200  203  ?   ?   ?   R . n 
C 3 201  PHE 201  204  ?   ?   ?   R . n 
C 3 202  LYS 202  205  ?   ?   ?   R . n 
C 3 203  ILE 203  206  ?   ?   ?   R . n 
C 3 204  TYR 204  207  ?   ?   ?   R . n 
C 3 205  SER 205  208  ?   ?   ?   R . n 
C 3 206  LYS 206  209  ?   ?   ?   R . n 
C 3 207  HIS 207  210  ?   ?   ?   R . n 
C 3 208  THR 208  211  ?   ?   ?   R . n 
C 3 209  PRO 209  212  ?   ?   ?   R . n 
C 3 210  ILE 210  213  ?   ?   ?   R . n 
C 3 211  ASN 211  214  ?   ?   ?   R . n 
C 3 212  LEU 212  215  ?   ?   ?   R . n 
C 3 213  VAL 213  216  ?   ?   ?   R . n 
C 3 214  ARG 214  217  ?   ?   ?   R . n 
C 3 215  GLY 215  218  ?   ?   ?   R . n 
C 3 216  LEU 216  219  ?   ?   ?   R . n 
C 3 217  PRO 217  220  ?   ?   ?   R . n 
C 3 218  GLN 218  221  ?   ?   ?   R . n 
C 3 219  GLY 219  222  ?   ?   ?   R . n 
C 3 220  PHE 220  223  ?   ?   ?   R . n 
C 3 221  SER 221  224  ?   ?   ?   R . n 
C 3 222  ALA 222  225  ?   ?   ?   R . n 
C 3 223  LEU 223  226  ?   ?   ?   R . n 
C 3 224  GLU 224  227  ?   ?   ?   R . n 
C 3 225  PRO 225  228  ?   ?   ?   R . n 
C 3 226  LEU 226  229  ?   ?   ?   R . n 
C 3 227  VAL 227  230  ?   ?   ?   R . n 
C 3 228  ASP 228  231  ?   ?   ?   R . n 
C 3 229  LEU 229  232  ?   ?   ?   R . n 
C 3 230  PRO 230  233  ?   ?   ?   R . n 
C 3 231  ILE 231  234  ?   ?   ?   R . n 
C 3 232  GLY 232  235  ?   ?   ?   R . n 
C 3 233  ILE 233  236  ?   ?   ?   R . n 
C 3 234  ASN 234  237  ?   ?   ?   R . n 
C 3 235  ILE 235  238  ?   ?   ?   R . n 
C 3 236  THR 236  239  ?   ?   ?   R . n 
C 3 237  ARG 237  240  ?   ?   ?   R . n 
C 3 238  PHE 238  241  ?   ?   ?   R . n 
C 3 239  GLN 239  242  ?   ?   ?   R . n 
C 3 240  THR 240  243  ?   ?   ?   R . n 
C 3 241  LEU 241  244  ?   ?   ?   R . n 
C 3 242  HIS 242  245  ?   ?   ?   R . n 
C 3 243  ARG 243  246  ?   ?   ?   R . n 
C 3 244  SER 244  247  ?   ?   ?   R . n 
C 3 245  TYR 245  248  ?   ?   ?   R . n 
C 3 246  LEU 246  249  ?   ?   ?   R . n 
C 3 247  THR 247  250  ?   ?   ?   R . n 
C 3 248  PRO 248  251  ?   ?   ?   R . n 
C 3 249  GLY 249  252  ?   ?   ?   R . n 
C 3 250  ASP 250  253  ?   ?   ?   R . n 
C 3 251  SER 251  254  ?   ?   ?   R . n 
C 3 252  SER 252  255  ?   ?   ?   R . n 
C 3 253  SER 253  256  ?   ?   ?   R . n 
C 3 254  GLY 254  257  ?   ?   ?   R . n 
C 3 255  TRP 255  258  ?   ?   ?   R . n 
C 3 256  THR 256  259  ?   ?   ?   R . n 
C 3 257  ALA 257  260  ?   ?   ?   R . n 
C 3 258  GLY 258  261  ?   ?   ?   R . n 
C 3 259  ALA 259  262  ?   ?   ?   R . n 
C 3 260  ALA 260  263  ?   ?   ?   R . n 
C 3 261  ALA 261  264  ?   ?   ?   R . n 
C 3 262  TYR 262  265  ?   ?   ?   R . n 
C 3 263  TYR 263  266  ?   ?   ?   R . n 
C 3 264  VAL 264  267  ?   ?   ?   R . n 
C 3 265  GLY 265  268  ?   ?   ?   R . n 
C 3 266  TYR 266  269  ?   ?   ?   R . n 
C 3 267  LEU 267  270  ?   ?   ?   R . n 
C 3 268  GLN 268  271  ?   ?   ?   R . n 
C 3 269  PRO 269  272  ?   ?   ?   R . n 
C 3 270  ARG 270  273  ?   ?   ?   R . n 
C 3 271  THR 271  274  ?   ?   ?   R . n 
C 3 272  PHE 272  275  ?   ?   ?   R . n 
C 3 273  LEU 273  276  ?   ?   ?   R . n 
C 3 274  LEU 274  277  ?   ?   ?   R . n 
C 3 275  LYS 275  278  ?   ?   ?   R . n 
C 3 276  TYR 276  279  ?   ?   ?   R . n 
C 3 277  ASN 277  280  ?   ?   ?   R . n 
C 3 278  GLU 278  281  ?   ?   ?   R . n 
C 3 279  ASN 279  282  ?   ?   ?   R . n 
C 3 280  GLY 280  283  ?   ?   ?   R . n 
C 3 281  THR 281  284  ?   ?   ?   R . n 
C 3 282  ILE 282  285  ?   ?   ?   R . n 
C 3 283  THR 283  286  ?   ?   ?   R . n 
C 3 284  ASP 284  287  ?   ?   ?   R . n 
C 3 285  ALA 285  288  ?   ?   ?   R . n 
C 3 286  VAL 286  289  ?   ?   ?   R . n 
C 3 287  ASP 287  290  ?   ?   ?   R . n 
C 3 288  CYS 288  291  ?   ?   ?   R . n 
C 3 289  ALA 289  292  ?   ?   ?   R . n 
C 3 290  LEU 290  293  ?   ?   ?   R . n 
C 3 291  ASP 291  294  ?   ?   ?   R . n 
C 3 292  PRO 292  295  ?   ?   ?   R . n 
C 3 293  LEU 293  296  ?   ?   ?   R . n 
C 3 294  SER 294  297  ?   ?   ?   R . n 
C 3 295  GLU 295  298  ?   ?   ?   R . n 
C 3 296  THR 296  299  ?   ?   ?   R . n 
C 3 297  LYS 297  300  ?   ?   ?   R . n 
C 3 298  CYS 298  301  ?   ?   ?   R . n 
C 3 299  THR 299  302  ?   ?   ?   R . n 
C 3 300  LEU 300  303  ?   ?   ?   R . n 
C 3 301  LYS 301  304  ?   ?   ?   R . n 
C 3 302  SER 302  305  ?   ?   ?   R . n 
C 3 303  PHE 303  306  ?   ?   ?   R . n 
C 3 304  THR 304  307  ?   ?   ?   R . n 
C 3 305  VAL 305  308  ?   ?   ?   R . n 
C 3 306  GLU 306  309  ?   ?   ?   R . n 
C 3 307  LYS 307  310  ?   ?   ?   R . n 
C 3 308  GLY 308  311  ?   ?   ?   R . n 
C 3 309  ILE 309  312  ?   ?   ?   R . n 
C 3 310  TYR 310  313  ?   ?   ?   R . n 
C 3 311  GLN 311  314  ?   ?   ?   R . n 
C 3 312  THR 312  315  ?   ?   ?   R . n 
C 3 313  SER 313  316  ?   ?   ?   R . n 
C 3 314  ASN 314  317  ?   ?   ?   R . n 
C 3 315  PHE 315  318  ?   ?   ?   R . n 
C 3 316  ARG 316  319  ?   ?   ?   R . n 
C 3 317  VAL 317  320  ?   ?   ?   R . n 
C 3 318  GLN 318  321  ?   ?   ?   R . n 
C 3 319  PRO 319  322  ?   ?   ?   R . n 
C 3 320  THR 320  323  ?   ?   ?   R . n 
C 3 321  GLU 321  324  ?   ?   ?   R . n 
C 3 322  SER 322  325  ?   ?   ?   R . n 
C 3 323  ILE 323  326  ?   ?   ?   R . n 
C 3 324  VAL 324  327  ?   ?   ?   R . n 
C 3 325  ARG 325  328  ?   ?   ?   R . n 
C 3 326  PHE 326  329  ?   ?   ?   R . n 
C 3 327  PRO 327  330  ?   ?   ?   R . n 
C 3 328  ASN 328  331  ?   ?   ?   R . n 
C 3 329  ILE 329  332  ?   ?   ?   R . n 
C 3 330  THR 330  333  ?   ?   ?   R . n 
C 3 331  ASN 331  334  334 ASN ASN R . n 
C 3 332  LEU 332  335  335 LEU LEU R . n 
C 3 333  CYS 333  336  336 CYS CYS R . n 
C 3 334  PRO 334  337  337 PRO PRO R . n 
C 3 335  PHE 335  338  338 PHE PHE R . n 
C 3 336  GLY 336  339  339 GLY GLY R . n 
C 3 337  GLU 337  340  340 GLU GLU R . n 
C 3 338  VAL 338  341  341 VAL VAL R . n 
C 3 339  PHE 339  342  342 PHE PHE R . n 
C 3 340  ASN 340  343  343 ASN ASN R . n 
C 3 341  ALA 341  344  344 ALA ALA R . n 
C 3 342  THR 342  345  345 THR THR R . n 
C 3 343  ARG 343  346  346 ARG ARG R . n 
C 3 344  PHE 344  347  347 PHE PHE R . n 
C 3 345  ALA 345  348  348 ALA ALA R . n 
C 3 346  SER 346  349  349 SER SER R . n 
C 3 347  VAL 347  350  350 VAL VAL R . n 
C 3 348  TYR 348  351  351 TYR TYR R . n 
C 3 349  ALA 349  352  352 ALA ALA R . n 
C 3 350  TRP 350  353  353 TRP TRP R . n 
C 3 351  ASN 351  354  354 ASN ASN R . n 
C 3 352  ARG 352  355  355 ARG ARG R . n 
C 3 353  LYS 353  356  356 LYS LYS R . n 
C 3 354  ARG 354  357  357 ARG ARG R . n 
C 3 355  ILE 355  358  358 ILE ILE R . n 
C 3 356  SER 356  359  359 SER SER R . n 
C 3 357  ASN 357  360  360 ASN ASN R . n 
C 3 358  CYS 358  361  361 CYS CYS R . n 
C 3 359  VAL 359  362  362 VAL VAL R . n 
C 3 360  ALA 360  363  363 ALA ALA R . n 
C 3 361  ASP 361  364  364 ASP ASP R . n 
C 3 362  TYR 362  365  365 TYR TYR R . n 
C 3 363  SER 363  366  366 SER SER R . n 
C 3 364  VAL 364  367  367 VAL VAL R . n 
C 3 365  LEU 365  368  368 LEU LEU R . n 
C 3 366  TYR 366  369  369 TYR TYR R . n 
C 3 367  ASN 367  370  370 ASN ASN R . n 
C 3 368  SER 368  371  371 SER SER R . n 
C 3 369  ALA 369  372  372 ALA ALA R . n 
C 3 370  SER 370  373  373 SER SER R . n 
C 3 371  PHE 371  374  374 PHE PHE R . n 
C 3 372  SER 372  375  375 SER SER R . n 
C 3 373  THR 373  376  376 THR THR R . n 
C 3 374  PHE 374  377  377 PHE PHE R . n 
C 3 375  LYS 375  378  378 LYS LYS R . n 
C 3 376  CYS 376  379  379 CYS CYS R . n 
C 3 377  TYR 377  380  380 TYR TYR R . n 
C 3 378  GLY 378  381  381 GLY GLY R . n 
C 3 379  VAL 379  382  382 VAL VAL R . n 
C 3 380  SER 380  383  383 SER SER R . n 
C 3 381  PRO 381  384  384 PRO PRO R . n 
C 3 382  THR 382  385  385 THR THR R . n 
C 3 383  LYS 383  386  386 LYS LYS R . n 
C 3 384  LEU 384  387  387 LEU LEU R . n 
C 3 385  ASN 385  388  388 ASN ASN R . n 
C 3 386  ASP 386  389  389 ASP ASP R . n 
C 3 387  LEU 387  390  390 LEU LEU R . n 
C 3 388  CYS 388  391  391 CYS CYS R . n 
C 3 389  PHE 389  392  392 PHE PHE R . n 
C 3 390  THR 390  393  393 THR THR R . n 
C 3 391  ASN 391  394  394 ASN ASN R . n 
C 3 392  VAL 392  395  395 VAL VAL R . n 
C 3 393  TYR 393  396  396 TYR TYR R . n 
C 3 394  ALA 394  397  397 ALA ALA R . n 
C 3 395  ASP 395  398  398 ASP ASP R . n 
C 3 396  SER 396  399  399 SER SER R . n 
C 3 397  PHE 397  400  400 PHE PHE R . n 
C 3 398  VAL 398  401  401 VAL VAL R . n 
C 3 399  ILE 399  402  402 ILE ILE R . n 
C 3 400  ARG 400  403  403 ARG ARG R . n 
C 3 401  GLY 401  404  404 GLY GLY R . n 
C 3 402  ASP 402  405  405 ASP ASP R . n 
C 3 403  GLU 403  406  406 GLU GLU R . n 
C 3 404  VAL 404  407  407 VAL VAL R . n 
C 3 405  ARG 405  408  408 ARG ARG R . n 
C 3 406  GLN 406  409  409 GLN GLN R . n 
C 3 407  ILE 407  410  410 ILE ILE R . n 
C 3 408  ALA 408  411  411 ALA ALA R . n 
C 3 409  PRO 409  412  412 PRO PRO R . n 
C 3 410  GLY 410  413  413 GLY GLY R . n 
C 3 411  GLN 411  414  414 GLN GLN R . n 
C 3 412  THR 412  415  415 THR THR R . n 
C 3 413  GLY 413  416  416 GLY GLY R . n 
C 3 414  ASN 414  417  417 ASN ASN R . n 
C 3 415  ILE 415  418  418 ILE ILE R . n 
C 3 416  ALA 416  419  419 ALA ALA R . n 
C 3 417  ASP 417  420  420 ASP ASP R . n 
C 3 418  TYR 418  421  421 TYR TYR R . n 
C 3 419  ASN 419  422  422 ASN ASN R . n 
C 3 420  TYR 420  423  423 TYR TYR R . n 
C 3 421  LYS 421  424  424 LYS LYS R . n 
C 3 422  LEU 422  425  425 LEU LEU R . n 
C 3 423  PRO 423  426  426 PRO PRO R . n 
C 3 424  ASP 424  427  427 ASP ASP R . n 
C 3 425  ASP 425  428  428 ASP ASP R . n 
C 3 426  PHE 426  429  429 PHE PHE R . n 
C 3 427  THR 427  430  430 THR THR R . n 
C 3 428  GLY 428  431  431 GLY GLY R . n 
C 3 429  CYS 429  432  432 CYS CYS R . n 
C 3 430  VAL 430  433  433 VAL VAL R . n 
C 3 431  ILE 431  434  434 ILE ILE R . n 
C 3 432  ALA 432  435  435 ALA ALA R . n 
C 3 433  TRP 433  436  436 TRP TRP R . n 
C 3 434  ASN 434  437  437 ASN ASN R . n 
C 3 435  SER 435  438  438 SER SER R . n 
C 3 436  ASN 436  439  439 ASN ASN R . n 
C 3 437  ASN 437  440  440 ASN ASN R . n 
C 3 438  LEU 438  441  441 LEU LEU R . n 
C 3 439  ASP 439  442  442 ASP ASP R . n 
C 3 440  SER 440  443  443 SER SER R . n 
C 3 441  LYS 441  444  444 LYS LYS R . n 
C 3 442  VAL 442  445  445 VAL VAL R . n 
C 3 443  GLY 443  446  446 GLY GLY R . n 
C 3 444  GLY 444  447  447 GLY GLY R . n 
C 3 445  ASN 445  448  448 ASN ASN R . n 
C 3 446  TYR 446  449  449 TYR TYR R . n 
C 3 447  ASN 447  450  450 ASN ASN R . n 
C 3 448  TYR 448  451  451 TYR TYR R . n 
C 3 449  LEU 449  452  452 LEU LEU R . n 
C 3 450  TYR 450  453  453 TYR TYR R . n 
C 3 451  ARG 451  454  454 ARG ARG R . n 
C 3 452  LEU 452  455  455 LEU LEU R . n 
C 3 453  PHE 453  456  456 PHE PHE R . n 
C 3 454  ARG 454  457  457 ARG ARG R . n 
C 3 455  LYS 455  458  458 LYS LYS R . n 
C 3 456  SER 456  459  459 SER SER R . n 
C 3 457  ASN 457  460  460 ASN ASN R . n 
C 3 458  LEU 458  461  461 LEU LEU R . n 
C 3 459  LYS 459  462  462 LYS LYS R . n 
C 3 460  PRO 460  463  463 PRO PRO R . n 
C 3 461  PHE 461  464  464 PHE PHE R . n 
C 3 462  GLU 462  465  465 GLU GLU R . n 
C 3 463  ARG 463  466  466 ARG ARG R . n 
C 3 464  ASP 464  467  467 ASP ASP R . n 
C 3 465  ILE 465  468  468 ILE ILE R . n 
C 3 466  SER 466  469  469 SER SER R . n 
C 3 467  THR 467  470  470 THR THR R . n 
C 3 468  GLU 468  471  471 GLU GLU R . n 
C 3 469  ILE 469  472  472 ILE ILE R . n 
C 3 470  TYR 470  473  473 TYR TYR R . n 
C 3 471  GLN 471  474  474 GLN GLN R . n 
C 3 472  ALA 472  475  475 ALA ALA R . n 
C 3 473  GLY 473  476  476 GLY GLY R . n 
C 3 474  SER 474  477  477 SER SER R . n 
C 3 475  THR 475  478  478 THR THR R . n 
C 3 476  PRO 476  479  479 PRO PRO R . n 
C 3 477  CYS 477  480  480 CYS CYS R . n 
C 3 478  ASN 478  481  481 ASN ASN R . n 
C 3 479  GLY 479  482  482 GLY GLY R . n 
C 3 480  VAL 480  483  483 VAL VAL R . n 
C 3 481  LYS 481  484  484 LYS LYS R . n 
C 3 482  GLY 482  485  485 GLY GLY R . n 
C 3 483  PHE 483  486  486 PHE PHE R . n 
C 3 484  ASN 484  487  487 ASN ASN R . n 
C 3 485  CYS 485  488  488 CYS CYS R . n 
C 3 486  TYR 486  489  489 TYR TYR R . n 
C 3 487  PHE 487  490  490 PHE PHE R . n 
C 3 488  PRO 488  491  491 PRO PRO R . n 
C 3 489  LEU 489  492  492 LEU LEU R . n 
C 3 490  GLN 490  493  493 GLN GLN R . n 
C 3 491  SER 491  494  494 SER SER R . n 
C 3 492  TYR 492  495  495 TYR TYR R . n 
C 3 493  GLY 493  496  496 GLY GLY R . n 
C 3 494  PHE 494  497  497 PHE PHE R . n 
C 3 495  GLN 495  498  498 GLN GLN R . n 
C 3 496  PRO 496  499  499 PRO PRO R . n 
C 3 497  THR 497  500  500 THR THR R . n 
C 3 498  TYR 498  501  501 TYR TYR R . n 
C 3 499  GLY 499  502  502 GLY GLY R . n 
C 3 500  VAL 500  503  503 VAL VAL R . n 
C 3 501  GLY 501  504  504 GLY GLY R . n 
C 3 502  TYR 502  505  505 TYR TYR R . n 
C 3 503  GLN 503  506  506 GLN GLN R . n 
C 3 504  PRO 504  507  507 PRO PRO R . n 
C 3 505  TYR 505  508  508 TYR TYR R . n 
C 3 506  ARG 506  509  509 ARG ARG R . n 
C 3 507  VAL 507  510  510 VAL VAL R . n 
C 3 508  VAL 508  511  511 VAL VAL R . n 
C 3 509  VAL 509  512  512 VAL VAL R . n 
C 3 510  LEU 510  513  513 LEU LEU R . n 
C 3 511  SER 511  514  514 SER SER R . n 
C 3 512  PHE 512  515  515 PHE PHE R . n 
C 3 513  GLU 513  516  516 GLU GLU R . n 
C 3 514  LEU 514  517  ?   ?   ?   R . n 
C 3 515  LEU 515  518  ?   ?   ?   R . n 
C 3 516  HIS 516  519  ?   ?   ?   R . n 
C 3 517  ALA 517  520  ?   ?   ?   R . n 
C 3 518  PRO 518  521  ?   ?   ?   R . n 
C 3 519  ALA 519  522  ?   ?   ?   R . n 
C 3 520  THR 520  523  ?   ?   ?   R . n 
C 3 521  VAL 521  524  ?   ?   ?   R . n 
C 3 522  CYS 522  525  ?   ?   ?   R . n 
C 3 523  GLY 523  526  ?   ?   ?   R . n 
C 3 524  PRO 524  527  ?   ?   ?   R . n 
C 3 525  LYS 525  528  ?   ?   ?   R . n 
C 3 526  LYS 526  529  ?   ?   ?   R . n 
C 3 527  SER 527  530  ?   ?   ?   R . n 
C 3 528  THR 528  531  ?   ?   ?   R . n 
C 3 529  ASN 529  532  ?   ?   ?   R . n 
C 3 530  LEU 530  533  ?   ?   ?   R . n 
C 3 531  VAL 531  534  ?   ?   ?   R . n 
C 3 532  LYS 532  535  ?   ?   ?   R . n 
C 3 533  ASN 533  536  ?   ?   ?   R . n 
C 3 534  LYS 534  537  ?   ?   ?   R . n 
C 3 535  CYS 535  538  ?   ?   ?   R . n 
C 3 536  VAL 536  539  ?   ?   ?   R . n 
C 3 537  ASN 537  540  ?   ?   ?   R . n 
C 3 538  PHE 538  541  ?   ?   ?   R . n 
C 3 539  ASN 539  542  ?   ?   ?   R . n 
C 3 540  PHE 540  543  ?   ?   ?   R . n 
C 3 541  ASN 541  544  ?   ?   ?   R . n 
C 3 542  GLY 542  545  ?   ?   ?   R . n 
C 3 543  LEU 543  546  ?   ?   ?   R . n 
C 3 544  THR 544  547  ?   ?   ?   R . n 
C 3 545  GLY 545  548  ?   ?   ?   R . n 
C 3 546  THR 546  549  ?   ?   ?   R . n 
C 3 547  GLY 547  550  ?   ?   ?   R . n 
C 3 548  VAL 548  551  ?   ?   ?   R . n 
C 3 549  LEU 549  552  ?   ?   ?   R . n 
C 3 550  THR 550  553  ?   ?   ?   R . n 
C 3 551  GLU 551  554  ?   ?   ?   R . n 
C 3 552  SER 552  555  ?   ?   ?   R . n 
C 3 553  ASN 553  556  ?   ?   ?   R . n 
C 3 554  LYS 554  557  ?   ?   ?   R . n 
C 3 555  LYS 555  558  ?   ?   ?   R . n 
C 3 556  PHE 556  559  ?   ?   ?   R . n 
C 3 557  LEU 557  560  ?   ?   ?   R . n 
C 3 558  PRO 558  561  ?   ?   ?   R . n 
C 3 559  PHE 559  562  ?   ?   ?   R . n 
C 3 560  GLN 560  563  ?   ?   ?   R . n 
C 3 561  GLN 561  564  ?   ?   ?   R . n 
C 3 562  PHE 562  565  ?   ?   ?   R . n 
C 3 563  GLY 563  566  ?   ?   ?   R . n 
C 3 564  ARG 564  567  ?   ?   ?   R . n 
C 3 565  ASP 565  568  ?   ?   ?   R . n 
C 3 566  ILE 566  569  ?   ?   ?   R . n 
C 3 567  ALA 567  570  ?   ?   ?   R . n 
C 3 568  ASP 568  571  ?   ?   ?   R . n 
C 3 569  THR 569  572  ?   ?   ?   R . n 
C 3 570  THR 570  573  ?   ?   ?   R . n 
C 3 571  ASP 571  574  ?   ?   ?   R . n 
C 3 572  ALA 572  575  ?   ?   ?   R . n 
C 3 573  VAL 573  576  ?   ?   ?   R . n 
C 3 574  ARG 574  577  ?   ?   ?   R . n 
C 3 575  ASP 575  578  ?   ?   ?   R . n 
C 3 576  PRO 576  579  ?   ?   ?   R . n 
C 3 577  GLN 577  580  ?   ?   ?   R . n 
C 3 578  THR 578  581  ?   ?   ?   R . n 
C 3 579  LEU 579  582  ?   ?   ?   R . n 
C 3 580  GLU 580  583  ?   ?   ?   R . n 
C 3 581  ILE 581  584  ?   ?   ?   R . n 
C 3 582  LEU 582  585  ?   ?   ?   R . n 
C 3 583  ASP 583  586  ?   ?   ?   R . n 
C 3 584  ILE 584  587  ?   ?   ?   R . n 
C 3 585  THR 585  588  ?   ?   ?   R . n 
C 3 586  PRO 586  589  ?   ?   ?   R . n 
C 3 587  CYS 587  590  ?   ?   ?   R . n 
C 3 588  SER 588  591  ?   ?   ?   R . n 
C 3 589  PHE 589  592  ?   ?   ?   R . n 
C 3 590  GLY 590  593  ?   ?   ?   R . n 
C 3 591  GLY 591  594  ?   ?   ?   R . n 
C 3 592  VAL 592  595  ?   ?   ?   R . n 
C 3 593  SER 593  596  ?   ?   ?   R . n 
C 3 594  VAL 594  597  ?   ?   ?   R . n 
C 3 595  ILE 595  598  ?   ?   ?   R . n 
C 3 596  THR 596  599  ?   ?   ?   R . n 
C 3 597  PRO 597  600  ?   ?   ?   R . n 
C 3 598  GLY 598  601  ?   ?   ?   R . n 
C 3 599  THR 599  602  ?   ?   ?   R . n 
C 3 600  ASN 600  603  ?   ?   ?   R . n 
C 3 601  THR 601  604  ?   ?   ?   R . n 
C 3 602  SER 602  605  ?   ?   ?   R . n 
C 3 603  ASN 603  606  ?   ?   ?   R . n 
C 3 604  GLN 604  607  ?   ?   ?   R . n 
C 3 605  VAL 605  608  ?   ?   ?   R . n 
C 3 606  ALA 606  609  ?   ?   ?   R . n 
C 3 607  VAL 607  610  ?   ?   ?   R . n 
C 3 608  LEU 608  611  ?   ?   ?   R . n 
C 3 609  TYR 609  612  ?   ?   ?   R . n 
C 3 610  GLN 610  613  ?   ?   ?   R . n 
C 3 611  GLY 611  614  ?   ?   ?   R . n 
C 3 612  VAL 612  615  ?   ?   ?   R . n 
C 3 613  ASN 613  616  ?   ?   ?   R . n 
C 3 614  CYS 614  617  ?   ?   ?   R . n 
C 3 615  THR 615  618  ?   ?   ?   R . n 
C 3 616  GLU 616  619  ?   ?   ?   R . n 
C 3 617  VAL 617  620  ?   ?   ?   R . n 
C 3 618  PRO 618  621  ?   ?   ?   R . n 
C 3 619  VAL 619  622  ?   ?   ?   R . n 
C 3 620  ALA 620  623  ?   ?   ?   R . n 
C 3 621  ILE 621  624  ?   ?   ?   R . n 
C 3 622  HIS 622  625  ?   ?   ?   R . n 
C 3 623  ALA 623  626  ?   ?   ?   R . n 
C 3 624  ASP 624  627  ?   ?   ?   R . n 
C 3 625  GLN 625  628  ?   ?   ?   R . n 
C 3 626  LEU 626  629  ?   ?   ?   R . n 
C 3 627  THR 627  630  ?   ?   ?   R . n 
C 3 628  PRO 628  631  ?   ?   ?   R . n 
C 3 629  THR 629  632  ?   ?   ?   R . n 
C 3 630  TRP 630  633  ?   ?   ?   R . n 
C 3 631  ARG 631  634  ?   ?   ?   R . n 
C 3 632  VAL 632  635  ?   ?   ?   R . n 
C 3 633  TYR 633  636  ?   ?   ?   R . n 
C 3 634  SER 634  637  ?   ?   ?   R . n 
C 3 635  THR 635  638  ?   ?   ?   R . n 
C 3 636  GLY 636  639  ?   ?   ?   R . n 
C 3 637  SER 637  640  ?   ?   ?   R . n 
C 3 638  ASN 638  641  ?   ?   ?   R . n 
C 3 639  VAL 639  642  ?   ?   ?   R . n 
C 3 640  PHE 640  643  ?   ?   ?   R . n 
C 3 641  GLN 641  644  ?   ?   ?   R . n 
C 3 642  THR 642  645  ?   ?   ?   R . n 
C 3 643  ARG 643  646  ?   ?   ?   R . n 
C 3 644  ALA 644  647  ?   ?   ?   R . n 
C 3 645  GLY 645  648  ?   ?   ?   R . n 
C 3 646  CYS 646  649  ?   ?   ?   R . n 
C 3 647  LEU 647  650  ?   ?   ?   R . n 
C 3 648  ILE 648  651  ?   ?   ?   R . n 
C 3 649  GLY 649  652  ?   ?   ?   R . n 
C 3 650  ALA 650  653  ?   ?   ?   R . n 
C 3 651  GLU 651  654  ?   ?   ?   R . n 
C 3 652  HIS 652  655  ?   ?   ?   R . n 
C 3 653  VAL 653  656  ?   ?   ?   R . n 
C 3 654  ASN 654  657  ?   ?   ?   R . n 
C 3 655  ASN 655  658  ?   ?   ?   R . n 
C 3 656  SER 656  659  ?   ?   ?   R . n 
C 3 657  TYR 657  660  ?   ?   ?   R . n 
C 3 658  GLU 658  661  ?   ?   ?   R . n 
C 3 659  CYS 659  662  ?   ?   ?   R . n 
C 3 660  ASP 660  663  ?   ?   ?   R . n 
C 3 661  ILE 661  664  ?   ?   ?   R . n 
C 3 662  PRO 662  665  ?   ?   ?   R . n 
C 3 663  ILE 663  666  ?   ?   ?   R . n 
C 3 664  GLY 664  667  ?   ?   ?   R . n 
C 3 665  ALA 665  668  ?   ?   ?   R . n 
C 3 666  GLY 666  669  ?   ?   ?   R . n 
C 3 667  ILE 667  670  ?   ?   ?   R . n 
C 3 668  CYS 668  671  ?   ?   ?   R . n 
C 3 669  ALA 669  672  ?   ?   ?   R . n 
C 3 670  SER 670  673  ?   ?   ?   R . n 
C 3 671  TYR 671  674  ?   ?   ?   R . n 
C 3 672  GLN 672  675  ?   ?   ?   R . n 
C 3 673  THR 673  676  ?   ?   ?   R . n 
C 3 674  GLN 674  677  ?   ?   ?   R . n 
C 3 675  THR 675  678  ?   ?   ?   R . n 
C 3 676  ASN 676  679  ?   ?   ?   R . n 
C 3 677  SER 677  680  ?   ?   ?   R . n 
C 3 678  PRO 678  681  ?   ?   ?   R . n 
C 3 679  GLY 679  682  ?   ?   ?   R . n 
C 3 680  SER 680  683  ?   ?   ?   R . n 
C 3 681  ALA 681  684  ?   ?   ?   R . n 
C 3 682  SER 682  685  ?   ?   ?   R . n 
C 3 683  SER 683  686  ?   ?   ?   R . n 
C 3 684  VAL 684  687  ?   ?   ?   R . n 
C 3 685  ALA 685  688  ?   ?   ?   R . n 
C 3 686  SER 686  689  ?   ?   ?   R . n 
C 3 687  GLN 687  690  ?   ?   ?   R . n 
C 3 688  SER 688  691  ?   ?   ?   R . n 
C 3 689  ILE 689  692  ?   ?   ?   R . n 
C 3 690  ILE 690  693  ?   ?   ?   R . n 
C 3 691  ALA 691  694  ?   ?   ?   R . n 
C 3 692  TYR 692  695  ?   ?   ?   R . n 
C 3 693  THR 693  696  ?   ?   ?   R . n 
C 3 694  MET 694  697  ?   ?   ?   R . n 
C 3 695  SER 695  698  ?   ?   ?   R . n 
C 3 696  LEU 696  699  ?   ?   ?   R . n 
C 3 697  GLY 697  700  ?   ?   ?   R . n 
C 3 698  VAL 698  701  ?   ?   ?   R . n 
C 3 699  GLU 699  702  ?   ?   ?   R . n 
C 3 700  ASN 700  703  ?   ?   ?   R . n 
C 3 701  SER 701  704  ?   ?   ?   R . n 
C 3 702  VAL 702  705  ?   ?   ?   R . n 
C 3 703  ALA 703  706  ?   ?   ?   R . n 
C 3 704  TYR 704  707  ?   ?   ?   R . n 
C 3 705  SER 705  708  ?   ?   ?   R . n 
C 3 706  ASN 706  709  ?   ?   ?   R . n 
C 3 707  ASN 707  710  ?   ?   ?   R . n 
C 3 708  SER 708  711  ?   ?   ?   R . n 
C 3 709  ILE 709  712  ?   ?   ?   R . n 
C 3 710  ALA 710  713  ?   ?   ?   R . n 
C 3 711  ILE 711  714  ?   ?   ?   R . n 
C 3 712  PRO 712  715  ?   ?   ?   R . n 
C 3 713  THR 713  716  ?   ?   ?   R . n 
C 3 714  ASN 714  717  ?   ?   ?   R . n 
C 3 715  PHE 715  718  ?   ?   ?   R . n 
C 3 716  THR 716  719  ?   ?   ?   R . n 
C 3 717  ILE 717  720  ?   ?   ?   R . n 
C 3 718  SER 718  721  ?   ?   ?   R . n 
C 3 719  VAL 719  722  ?   ?   ?   R . n 
C 3 720  THR 720  723  ?   ?   ?   R . n 
C 3 721  THR 721  724  ?   ?   ?   R . n 
C 3 722  GLU 722  725  ?   ?   ?   R . n 
C 3 723  ILE 723  726  ?   ?   ?   R . n 
C 3 724  LEU 724  727  ?   ?   ?   R . n 
C 3 725  PRO 725  728  ?   ?   ?   R . n 
C 3 726  VAL 726  729  ?   ?   ?   R . n 
C 3 727  SER 727  730  ?   ?   ?   R . n 
C 3 728  MET 728  731  ?   ?   ?   R . n 
C 3 729  THR 729  732  ?   ?   ?   R . n 
C 3 730  LYS 730  733  ?   ?   ?   R . n 
C 3 731  THR 731  734  ?   ?   ?   R . n 
C 3 732  SER 732  735  ?   ?   ?   R . n 
C 3 733  VAL 733  736  ?   ?   ?   R . n 
C 3 734  ASP 734  737  ?   ?   ?   R . n 
C 3 735  CYS 735  738  ?   ?   ?   R . n 
C 3 736  THR 736  739  ?   ?   ?   R . n 
C 3 737  MET 737  740  ?   ?   ?   R . n 
C 3 738  TYR 738  741  ?   ?   ?   R . n 
C 3 739  ILE 739  742  ?   ?   ?   R . n 
C 3 740  CYS 740  743  ?   ?   ?   R . n 
C 3 741  GLY 741  744  ?   ?   ?   R . n 
C 3 742  ASP 742  745  ?   ?   ?   R . n 
C 3 743  SER 743  746  ?   ?   ?   R . n 
C 3 744  THR 744  747  ?   ?   ?   R . n 
C 3 745  GLU 745  748  ?   ?   ?   R . n 
C 3 746  CYS 746  749  ?   ?   ?   R . n 
C 3 747  SER 747  750  ?   ?   ?   R . n 
C 3 748  ASN 748  751  ?   ?   ?   R . n 
C 3 749  LEU 749  752  ?   ?   ?   R . n 
C 3 750  LEU 750  753  ?   ?   ?   R . n 
C 3 751  LEU 751  754  ?   ?   ?   R . n 
C 3 752  GLN 752  755  ?   ?   ?   R . n 
C 3 753  TYR 753  756  ?   ?   ?   R . n 
C 3 754  GLY 754  757  ?   ?   ?   R . n 
C 3 755  SER 755  758  ?   ?   ?   R . n 
C 3 756  PHE 756  759  ?   ?   ?   R . n 
C 3 757  CYS 757  760  ?   ?   ?   R . n 
C 3 758  THR 758  761  ?   ?   ?   R . n 
C 3 759  GLN 759  762  ?   ?   ?   R . n 
C 3 760  LEU 760  763  ?   ?   ?   R . n 
C 3 761  ASN 761  764  ?   ?   ?   R . n 
C 3 762  ARG 762  765  ?   ?   ?   R . n 
C 3 763  ALA 763  766  ?   ?   ?   R . n 
C 3 764  LEU 764  767  ?   ?   ?   R . n 
C 3 765  THR 765  768  ?   ?   ?   R . n 
C 3 766  GLY 766  769  ?   ?   ?   R . n 
C 3 767  ILE 767  770  ?   ?   ?   R . n 
C 3 768  ALA 768  771  ?   ?   ?   R . n 
C 3 769  VAL 769  772  ?   ?   ?   R . n 
C 3 770  GLU 770  773  ?   ?   ?   R . n 
C 3 771  GLN 771  774  ?   ?   ?   R . n 
C 3 772  ASP 772  775  ?   ?   ?   R . n 
C 3 773  LYS 773  776  ?   ?   ?   R . n 
C 3 774  ASN 774  777  ?   ?   ?   R . n 
C 3 775  THR 775  778  ?   ?   ?   R . n 
C 3 776  GLN 776  779  ?   ?   ?   R . n 
C 3 777  GLU 777  780  ?   ?   ?   R . n 
C 3 778  VAL 778  781  ?   ?   ?   R . n 
C 3 779  PHE 779  782  ?   ?   ?   R . n 
C 3 780  ALA 780  783  ?   ?   ?   R . n 
C 3 781  GLN 781  784  ?   ?   ?   R . n 
C 3 782  VAL 782  785  ?   ?   ?   R . n 
C 3 783  LYS 783  786  ?   ?   ?   R . n 
C 3 784  GLN 784  787  ?   ?   ?   R . n 
C 3 785  ILE 785  788  ?   ?   ?   R . n 
C 3 786  TYR 786  789  ?   ?   ?   R . n 
C 3 787  LYS 787  790  ?   ?   ?   R . n 
C 3 788  THR 788  791  ?   ?   ?   R . n 
C 3 789  PRO 789  792  ?   ?   ?   R . n 
C 3 790  PRO 790  793  ?   ?   ?   R . n 
C 3 791  ILE 791  794  ?   ?   ?   R . n 
C 3 792  LYS 792  795  ?   ?   ?   R . n 
C 3 793  ASP 793  796  ?   ?   ?   R . n 
C 3 794  PHE 794  797  ?   ?   ?   R . n 
C 3 795  GLY 795  798  ?   ?   ?   R . n 
C 3 796  GLY 796  799  ?   ?   ?   R . n 
C 3 797  PHE 797  800  ?   ?   ?   R . n 
C 3 798  ASN 798  801  ?   ?   ?   R . n 
C 3 799  PHE 799  802  ?   ?   ?   R . n 
C 3 800  SER 800  803  ?   ?   ?   R . n 
C 3 801  GLN 801  804  ?   ?   ?   R . n 
C 3 802  ILE 802  805  ?   ?   ?   R . n 
C 3 803  LEU 803  806  ?   ?   ?   R . n 
C 3 804  PRO 804  807  ?   ?   ?   R . n 
C 3 805  ASP 805  808  ?   ?   ?   R . n 
C 3 806  PRO 806  809  ?   ?   ?   R . n 
C 3 807  SER 807  810  ?   ?   ?   R . n 
C 3 808  LYS 808  811  ?   ?   ?   R . n 
C 3 809  PRO 809  812  ?   ?   ?   R . n 
C 3 810  SER 810  813  ?   ?   ?   R . n 
C 3 811  LYS 811  814  ?   ?   ?   R . n 
C 3 812  ARG 812  815  ?   ?   ?   R . n 
C 3 813  SER 813  816  ?   ?   ?   R . n 
C 3 814  PRO 814  817  ?   ?   ?   R . n 
C 3 815  ILE 815  818  ?   ?   ?   R . n 
C 3 816  GLU 816  819  ?   ?   ?   R . n 
C 3 817  ASP 817  820  ?   ?   ?   R . n 
C 3 818  LEU 818  821  ?   ?   ?   R . n 
C 3 819  LEU 819  822  ?   ?   ?   R . n 
C 3 820  PHE 820  823  ?   ?   ?   R . n 
C 3 821  ASN 821  824  ?   ?   ?   R . n 
C 3 822  LYS 822  825  ?   ?   ?   R . n 
C 3 823  VAL 823  826  ?   ?   ?   R . n 
C 3 824  THR 824  827  ?   ?   ?   R . n 
C 3 825  LEU 825  828  ?   ?   ?   R . n 
C 3 826  ALA 826  829  ?   ?   ?   R . n 
C 3 827  ASP 827  830  ?   ?   ?   R . n 
C 3 828  ALA 828  831  ?   ?   ?   R . n 
C 3 829  GLY 829  832  ?   ?   ?   R . n 
C 3 830  PHE 830  833  ?   ?   ?   R . n 
C 3 831  ILE 831  834  ?   ?   ?   R . n 
C 3 832  LYS 832  835  ?   ?   ?   R . n 
C 3 833  GLN 833  836  ?   ?   ?   R . n 
C 3 834  TYR 834  837  ?   ?   ?   R . n 
C 3 835  GLY 835  838  ?   ?   ?   R . n 
C 3 836  ASP 836  839  ?   ?   ?   R . n 
C 3 837  CYS 837  840  ?   ?   ?   R . n 
C 3 838  LEU 838  841  ?   ?   ?   R . n 
C 3 839  GLY 839  842  ?   ?   ?   R . n 
C 3 840  ASP 840  843  ?   ?   ?   R . n 
C 3 841  ILE 841  844  ?   ?   ?   R . n 
C 3 842  ALA 842  845  ?   ?   ?   R . n 
C 3 843  ALA 843  846  ?   ?   ?   R . n 
C 3 844  ARG 844  847  ?   ?   ?   R . n 
C 3 845  ASP 845  848  ?   ?   ?   R . n 
C 3 846  LEU 846  849  ?   ?   ?   R . n 
C 3 847  ILE 847  850  ?   ?   ?   R . n 
C 3 848  CYS 848  851  ?   ?   ?   R . n 
C 3 849  ALA 849  852  ?   ?   ?   R . n 
C 3 850  GLN 850  853  ?   ?   ?   R . n 
C 3 851  LYS 851  854  ?   ?   ?   R . n 
C 3 852  PHE 852  855  ?   ?   ?   R . n 
C 3 853  ASN 853  856  ?   ?   ?   R . n 
C 3 854  GLY 854  857  ?   ?   ?   R . n 
C 3 855  LEU 855  858  ?   ?   ?   R . n 
C 3 856  THR 856  859  ?   ?   ?   R . n 
C 3 857  VAL 857  860  ?   ?   ?   R . n 
C 3 858  LEU 858  861  ?   ?   ?   R . n 
C 3 859  PRO 859  862  ?   ?   ?   R . n 
C 3 860  PRO 860  863  ?   ?   ?   R . n 
C 3 861  LEU 861  864  ?   ?   ?   R . n 
C 3 862  LEU 862  865  ?   ?   ?   R . n 
C 3 863  THR 863  866  ?   ?   ?   R . n 
C 3 864  ASP 864  867  ?   ?   ?   R . n 
C 3 865  GLU 865  868  ?   ?   ?   R . n 
C 3 866  MET 866  869  ?   ?   ?   R . n 
C 3 867  ILE 867  870  ?   ?   ?   R . n 
C 3 868  ALA 868  871  ?   ?   ?   R . n 
C 3 869  GLN 869  872  ?   ?   ?   R . n 
C 3 870  TYR 870  873  ?   ?   ?   R . n 
C 3 871  THR 871  874  ?   ?   ?   R . n 
C 3 872  SER 872  875  ?   ?   ?   R . n 
C 3 873  ALA 873  876  ?   ?   ?   R . n 
C 3 874  LEU 874  877  ?   ?   ?   R . n 
C 3 875  LEU 875  878  ?   ?   ?   R . n 
C 3 876  ALA 876  879  ?   ?   ?   R . n 
C 3 877  GLY 877  880  ?   ?   ?   R . n 
C 3 878  THR 878  881  ?   ?   ?   R . n 
C 3 879  ILE 879  882  ?   ?   ?   R . n 
C 3 880  THR 880  883  ?   ?   ?   R . n 
C 3 881  SER 881  884  ?   ?   ?   R . n 
C 3 882  GLY 882  885  ?   ?   ?   R . n 
C 3 883  TRP 883  886  ?   ?   ?   R . n 
C 3 884  THR 884  887  ?   ?   ?   R . n 
C 3 885  PHE 885  888  ?   ?   ?   R . n 
C 3 886  GLY 886  889  ?   ?   ?   R . n 
C 3 887  ALA 887  890  ?   ?   ?   R . n 
C 3 888  GLY 888  891  ?   ?   ?   R . n 
C 3 889  PRO 889  892  ?   ?   ?   R . n 
C 3 890  ALA 890  893  ?   ?   ?   R . n 
C 3 891  LEU 891  894  ?   ?   ?   R . n 
C 3 892  GLN 892  895  ?   ?   ?   R . n 
C 3 893  ILE 893  896  ?   ?   ?   R . n 
C 3 894  PRO 894  897  ?   ?   ?   R . n 
C 3 895  PHE 895  898  ?   ?   ?   R . n 
C 3 896  PRO 896  899  ?   ?   ?   R . n 
C 3 897  MET 897  900  ?   ?   ?   R . n 
C 3 898  GLN 898  901  ?   ?   ?   R . n 
C 3 899  MET 899  902  ?   ?   ?   R . n 
C 3 900  ALA 900  903  ?   ?   ?   R . n 
C 3 901  TYR 901  904  ?   ?   ?   R . n 
C 3 902  ARG 902  905  ?   ?   ?   R . n 
C 3 903  PHE 903  906  ?   ?   ?   R . n 
C 3 904  ASN 904  907  ?   ?   ?   R . n 
C 3 905  GLY 905  908  ?   ?   ?   R . n 
C 3 906  ILE 906  909  ?   ?   ?   R . n 
C 3 907  GLY 907  910  ?   ?   ?   R . n 
C 3 908  VAL 908  911  ?   ?   ?   R . n 
C 3 909  THR 909  912  ?   ?   ?   R . n 
C 3 910  GLN 910  913  ?   ?   ?   R . n 
C 3 911  ASN 911  914  ?   ?   ?   R . n 
C 3 912  VAL 912  915  ?   ?   ?   R . n 
C 3 913  LEU 913  916  ?   ?   ?   R . n 
C 3 914  TYR 914  917  ?   ?   ?   R . n 
C 3 915  GLU 915  918  ?   ?   ?   R . n 
C 3 916  ASN 916  919  ?   ?   ?   R . n 
C 3 917  GLN 917  920  ?   ?   ?   R . n 
C 3 918  LYS 918  921  ?   ?   ?   R . n 
C 3 919  LEU 919  922  ?   ?   ?   R . n 
C 3 920  ILE 920  923  ?   ?   ?   R . n 
C 3 921  ALA 921  924  ?   ?   ?   R . n 
C 3 922  ASN 922  925  ?   ?   ?   R . n 
C 3 923  GLN 923  926  ?   ?   ?   R . n 
C 3 924  PHE 924  927  ?   ?   ?   R . n 
C 3 925  ASN 925  928  ?   ?   ?   R . n 
C 3 926  SER 926  929  ?   ?   ?   R . n 
C 3 927  ALA 927  930  ?   ?   ?   R . n 
C 3 928  ILE 928  931  ?   ?   ?   R . n 
C 3 929  GLY 929  932  ?   ?   ?   R . n 
C 3 930  LYS 930  933  ?   ?   ?   R . n 
C 3 931  ILE 931  934  ?   ?   ?   R . n 
C 3 932  GLN 932  935  ?   ?   ?   R . n 
C 3 933  ASP 933  936  ?   ?   ?   R . n 
C 3 934  SER 934  937  ?   ?   ?   R . n 
C 3 935  LEU 935  938  ?   ?   ?   R . n 
C 3 936  SER 936  939  ?   ?   ?   R . n 
C 3 937  SER 937  940  ?   ?   ?   R . n 
C 3 938  THR 938  941  ?   ?   ?   R . n 
C 3 939  PRO 939  942  ?   ?   ?   R . n 
C 3 940  SER 940  943  ?   ?   ?   R . n 
C 3 941  ALA 941  944  ?   ?   ?   R . n 
C 3 942  LEU 942  945  ?   ?   ?   R . n 
C 3 943  GLY 943  946  ?   ?   ?   R . n 
C 3 944  LYS 944  947  ?   ?   ?   R . n 
C 3 945  LEU 945  948  ?   ?   ?   R . n 
C 3 946  GLN 946  949  ?   ?   ?   R . n 
C 3 947  ASP 947  950  ?   ?   ?   R . n 
C 3 948  VAL 948  951  ?   ?   ?   R . n 
C 3 949  VAL 949  952  ?   ?   ?   R . n 
C 3 950  ASN 950  953  ?   ?   ?   R . n 
C 3 951  GLN 951  954  ?   ?   ?   R . n 
C 3 952  ASN 952  955  ?   ?   ?   R . n 
C 3 953  ALA 953  956  ?   ?   ?   R . n 
C 3 954  GLN 954  957  ?   ?   ?   R . n 
C 3 955  ALA 955  958  ?   ?   ?   R . n 
C 3 956  LEU 956  959  ?   ?   ?   R . n 
C 3 957  ASN 957  960  ?   ?   ?   R . n 
C 3 958  THR 958  961  ?   ?   ?   R . n 
C 3 959  LEU 959  962  ?   ?   ?   R . n 
C 3 960  VAL 960  963  ?   ?   ?   R . n 
C 3 961  LYS 961  964  ?   ?   ?   R . n 
C 3 962  GLN 962  965  ?   ?   ?   R . n 
C 3 963  LEU 963  966  ?   ?   ?   R . n 
C 3 964  SER 964  967  ?   ?   ?   R . n 
C 3 965  SER 965  968  ?   ?   ?   R . n 
C 3 966  ASN 966  969  ?   ?   ?   R . n 
C 3 967  PHE 967  970  ?   ?   ?   R . n 
C 3 968  GLY 968  971  ?   ?   ?   R . n 
C 3 969  ALA 969  972  ?   ?   ?   R . n 
C 3 970  ILE 970  973  ?   ?   ?   R . n 
C 3 971  SER 971  974  ?   ?   ?   R . n 
C 3 972  SER 972  975  ?   ?   ?   R . n 
C 3 973  VAL 973  976  ?   ?   ?   R . n 
C 3 974  LEU 974  977  ?   ?   ?   R . n 
C 3 975  ASN 975  978  ?   ?   ?   R . n 
C 3 976  ASP 976  979  ?   ?   ?   R . n 
C 3 977  ILE 977  980  ?   ?   ?   R . n 
C 3 978  LEU 978  981  ?   ?   ?   R . n 
C 3 979  SER 979  982  ?   ?   ?   R . n 
C 3 980  ARG 980  983  ?   ?   ?   R . n 
C 3 981  LEU 981  984  ?   ?   ?   R . n 
C 3 982  ASP 982  985  ?   ?   ?   R . n 
C 3 983  PRO 983  986  ?   ?   ?   R . n 
C 3 984  PRO 984  987  ?   ?   ?   R . n 
C 3 985  GLU 985  988  ?   ?   ?   R . n 
C 3 986  ALA 986  989  ?   ?   ?   R . n 
C 3 987  GLU 987  990  ?   ?   ?   R . n 
C 3 988  VAL 988  991  ?   ?   ?   R . n 
C 3 989  GLN 989  992  ?   ?   ?   R . n 
C 3 990  ILE 990  993  ?   ?   ?   R . n 
C 3 991  ASP 991  994  ?   ?   ?   R . n 
C 3 992  ARG 992  995  ?   ?   ?   R . n 
C 3 993  LEU 993  996  ?   ?   ?   R . n 
C 3 994  ILE 994  997  ?   ?   ?   R . n 
C 3 995  THR 995  998  ?   ?   ?   R . n 
C 3 996  GLY 996  999  ?   ?   ?   R . n 
C 3 997  ARG 997  1000 ?   ?   ?   R . n 
C 3 998  LEU 998  1001 ?   ?   ?   R . n 
C 3 999  GLN 999  1002 ?   ?   ?   R . n 
C 3 1000 SER 1000 1003 ?   ?   ?   R . n 
C 3 1001 LEU 1001 1004 ?   ?   ?   R . n 
C 3 1002 GLN 1002 1005 ?   ?   ?   R . n 
C 3 1003 THR 1003 1006 ?   ?   ?   R . n 
C 3 1004 TYR 1004 1007 ?   ?   ?   R . n 
C 3 1005 VAL 1005 1008 ?   ?   ?   R . n 
C 3 1006 THR 1006 1009 ?   ?   ?   R . n 
C 3 1007 GLN 1007 1010 ?   ?   ?   R . n 
C 3 1008 GLN 1008 1011 ?   ?   ?   R . n 
C 3 1009 LEU 1009 1012 ?   ?   ?   R . n 
C 3 1010 ILE 1010 1013 ?   ?   ?   R . n 
C 3 1011 ARG 1011 1014 ?   ?   ?   R . n 
C 3 1012 ALA 1012 1015 ?   ?   ?   R . n 
C 3 1013 ALA 1013 1016 ?   ?   ?   R . n 
C 3 1014 GLU 1014 1017 ?   ?   ?   R . n 
C 3 1015 ILE 1015 1018 ?   ?   ?   R . n 
C 3 1016 ARG 1016 1019 ?   ?   ?   R . n 
C 3 1017 ALA 1017 1020 ?   ?   ?   R . n 
C 3 1018 SER 1018 1021 ?   ?   ?   R . n 
C 3 1019 ALA 1019 1022 ?   ?   ?   R . n 
C 3 1020 ASN 1020 1023 ?   ?   ?   R . n 
C 3 1021 LEU 1021 1024 ?   ?   ?   R . n 
C 3 1022 ALA 1022 1025 ?   ?   ?   R . n 
C 3 1023 ALA 1023 1026 ?   ?   ?   R . n 
C 3 1024 THR 1024 1027 ?   ?   ?   R . n 
C 3 1025 LYS 1025 1028 ?   ?   ?   R . n 
C 3 1026 MET 1026 1029 ?   ?   ?   R . n 
C 3 1027 SER 1027 1030 ?   ?   ?   R . n 
C 3 1028 GLU 1028 1031 ?   ?   ?   R . n 
C 3 1029 CYS 1029 1032 ?   ?   ?   R . n 
C 3 1030 VAL 1030 1033 ?   ?   ?   R . n 
C 3 1031 LEU 1031 1034 ?   ?   ?   R . n 
C 3 1032 GLY 1032 1035 ?   ?   ?   R . n 
C 3 1033 GLN 1033 1036 ?   ?   ?   R . n 
C 3 1034 SER 1034 1037 ?   ?   ?   R . n 
C 3 1035 LYS 1035 1038 ?   ?   ?   R . n 
C 3 1036 ARG 1036 1039 ?   ?   ?   R . n 
C 3 1037 VAL 1037 1040 ?   ?   ?   R . n 
C 3 1038 ASP 1038 1041 ?   ?   ?   R . n 
C 3 1039 PHE 1039 1042 ?   ?   ?   R . n 
C 3 1040 CYS 1040 1043 ?   ?   ?   R . n 
C 3 1041 GLY 1041 1044 ?   ?   ?   R . n 
C 3 1042 LYS 1042 1045 ?   ?   ?   R . n 
C 3 1043 GLY 1043 1046 ?   ?   ?   R . n 
C 3 1044 TYR 1044 1047 ?   ?   ?   R . n 
C 3 1045 HIS 1045 1048 ?   ?   ?   R . n 
C 3 1046 LEU 1046 1049 ?   ?   ?   R . n 
C 3 1047 MET 1047 1050 ?   ?   ?   R . n 
C 3 1048 SER 1048 1051 ?   ?   ?   R . n 
C 3 1049 PHE 1049 1052 ?   ?   ?   R . n 
C 3 1050 PRO 1050 1053 ?   ?   ?   R . n 
C 3 1051 GLN 1051 1054 ?   ?   ?   R . n 
C 3 1052 SER 1052 1055 ?   ?   ?   R . n 
C 3 1053 ALA 1053 1056 ?   ?   ?   R . n 
C 3 1054 PRO 1054 1057 ?   ?   ?   R . n 
C 3 1055 HIS 1055 1058 ?   ?   ?   R . n 
C 3 1056 GLY 1056 1059 ?   ?   ?   R . n 
C 3 1057 VAL 1057 1060 ?   ?   ?   R . n 
C 3 1058 VAL 1058 1061 ?   ?   ?   R . n 
C 3 1059 PHE 1059 1062 ?   ?   ?   R . n 
C 3 1060 LEU 1060 1063 ?   ?   ?   R . n 
C 3 1061 HIS 1061 1064 ?   ?   ?   R . n 
C 3 1062 VAL 1062 1065 ?   ?   ?   R . n 
C 3 1063 THR 1063 1066 ?   ?   ?   R . n 
C 3 1064 TYR 1064 1067 ?   ?   ?   R . n 
C 3 1065 VAL 1065 1068 ?   ?   ?   R . n 
C 3 1066 PRO 1066 1069 ?   ?   ?   R . n 
C 3 1067 ALA 1067 1070 ?   ?   ?   R . n 
C 3 1068 GLN 1068 1071 ?   ?   ?   R . n 
C 3 1069 GLU 1069 1072 ?   ?   ?   R . n 
C 3 1070 LYS 1070 1073 ?   ?   ?   R . n 
C 3 1071 ASN 1071 1074 ?   ?   ?   R . n 
C 3 1072 PHE 1072 1075 ?   ?   ?   R . n 
C 3 1073 THR 1073 1076 ?   ?   ?   R . n 
C 3 1074 THR 1074 1077 ?   ?   ?   R . n 
C 3 1075 ALA 1075 1078 ?   ?   ?   R . n 
C 3 1076 PRO 1076 1079 ?   ?   ?   R . n 
C 3 1077 ALA 1077 1080 ?   ?   ?   R . n 
C 3 1078 ILE 1078 1081 ?   ?   ?   R . n 
C 3 1079 CYS 1079 1082 ?   ?   ?   R . n 
C 3 1080 HIS 1080 1083 ?   ?   ?   R . n 
C 3 1081 ASP 1081 1084 ?   ?   ?   R . n 
C 3 1082 GLY 1082 1085 ?   ?   ?   R . n 
C 3 1083 LYS 1083 1086 ?   ?   ?   R . n 
C 3 1084 ALA 1084 1087 ?   ?   ?   R . n 
C 3 1085 HIS 1085 1088 ?   ?   ?   R . n 
C 3 1086 PHE 1086 1089 ?   ?   ?   R . n 
C 3 1087 PRO 1087 1090 ?   ?   ?   R . n 
C 3 1088 ARG 1088 1091 ?   ?   ?   R . n 
C 3 1089 GLU 1089 1092 ?   ?   ?   R . n 
C 3 1090 GLY 1090 1093 ?   ?   ?   R . n 
C 3 1091 VAL 1091 1094 ?   ?   ?   R . n 
C 3 1092 PHE 1092 1095 ?   ?   ?   R . n 
C 3 1093 VAL 1093 1096 ?   ?   ?   R . n 
C 3 1094 SER 1094 1097 ?   ?   ?   R . n 
C 3 1095 ASN 1095 1098 ?   ?   ?   R . n 
C 3 1096 GLY 1096 1099 ?   ?   ?   R . n 
C 3 1097 THR 1097 1100 ?   ?   ?   R . n 
C 3 1098 HIS 1098 1101 ?   ?   ?   R . n 
C 3 1099 TRP 1099 1102 ?   ?   ?   R . n 
C 3 1100 PHE 1100 1103 ?   ?   ?   R . n 
C 3 1101 VAL 1101 1104 ?   ?   ?   R . n 
C 3 1102 THR 1102 1105 ?   ?   ?   R . n 
C 3 1103 GLN 1103 1106 ?   ?   ?   R . n 
C 3 1104 ARG 1104 1107 ?   ?   ?   R . n 
C 3 1105 ASN 1105 1108 ?   ?   ?   R . n 
C 3 1106 PHE 1106 1109 ?   ?   ?   R . n 
C 3 1107 TYR 1107 1110 ?   ?   ?   R . n 
C 3 1108 GLU 1108 1111 ?   ?   ?   R . n 
C 3 1109 PRO 1109 1112 ?   ?   ?   R . n 
C 3 1110 GLN 1110 1113 ?   ?   ?   R . n 
C 3 1111 ILE 1111 1114 ?   ?   ?   R . n 
C 3 1112 ILE 1112 1115 ?   ?   ?   R . n 
C 3 1113 THR 1113 1116 ?   ?   ?   R . n 
C 3 1114 THR 1114 1117 ?   ?   ?   R . n 
C 3 1115 ASP 1115 1118 ?   ?   ?   R . n 
C 3 1116 ASN 1116 1119 ?   ?   ?   R . n 
C 3 1117 THR 1117 1120 ?   ?   ?   R . n 
C 3 1118 PHE 1118 1121 ?   ?   ?   R . n 
C 3 1119 VAL 1119 1122 ?   ?   ?   R . n 
C 3 1120 SER 1120 1123 ?   ?   ?   R . n 
C 3 1121 GLY 1121 1124 ?   ?   ?   R . n 
C 3 1122 ASN 1122 1125 ?   ?   ?   R . n 
C 3 1123 CYS 1123 1126 ?   ?   ?   R . n 
C 3 1124 ASP 1124 1127 ?   ?   ?   R . n 
C 3 1125 VAL 1125 1128 ?   ?   ?   R . n 
C 3 1126 VAL 1126 1129 ?   ?   ?   R . n 
C 3 1127 ILE 1127 1130 ?   ?   ?   R . n 
C 3 1128 GLY 1128 1131 ?   ?   ?   R . n 
C 3 1129 ILE 1129 1132 ?   ?   ?   R . n 
C 3 1130 VAL 1130 1133 ?   ?   ?   R . n 
C 3 1131 ASN 1131 1134 ?   ?   ?   R . n 
C 3 1132 ASN 1132 1135 ?   ?   ?   R . n 
C 3 1133 THR 1133 1136 ?   ?   ?   R . n 
C 3 1134 VAL 1134 1137 ?   ?   ?   R . n 
C 3 1135 TYR 1135 1138 ?   ?   ?   R . n 
C 3 1136 ASP 1136 1139 ?   ?   ?   R . n 
C 3 1137 PRO 1137 1140 ?   ?   ?   R . n 
C 3 1138 LEU 1138 1141 ?   ?   ?   R . n 
C 3 1139 GLN 1139 1142 ?   ?   ?   R . n 
C 3 1140 PRO 1140 1143 ?   ?   ?   R . n 
C 3 1141 GLU 1141 1144 ?   ?   ?   R . n 
C 3 1142 LEU 1142 1145 ?   ?   ?   R . n 
C 3 1143 ASP 1143 1146 ?   ?   ?   R . n 
C 3 1144 SER 1144 1147 ?   ?   ?   R . n 
C 3 1145 PHE 1145 1148 ?   ?   ?   R . n 
C 3 1146 LYS 1146 1149 ?   ?   ?   R . n 
C 3 1147 GLU 1147 1150 ?   ?   ?   R . n 
C 3 1148 GLU 1148 1151 ?   ?   ?   R . n 
C 3 1149 LEU 1149 1152 ?   ?   ?   R . n 
C 3 1150 ASP 1150 1153 ?   ?   ?   R . n 
C 3 1151 LYS 1151 1154 ?   ?   ?   R . n 
C 3 1152 TYR 1152 1155 ?   ?   ?   R . n 
C 3 1153 PHE 1153 1156 ?   ?   ?   R . n 
C 3 1154 LYS 1154 1157 ?   ?   ?   R . n 
C 3 1155 ASN 1155 1158 ?   ?   ?   R . n 
C 3 1156 HIS 1156 1159 ?   ?   ?   R . n 
C 3 1157 THR 1157 1160 ?   ?   ?   R . n 
C 3 1158 SER 1158 1161 ?   ?   ?   R . n 
C 3 1159 PRO 1159 1162 ?   ?   ?   R . n 
C 3 1160 ASP 1160 1163 ?   ?   ?   R . n 
C 3 1161 VAL 1161 1164 ?   ?   ?   R . n 
C 3 1162 ASP 1162 1165 ?   ?   ?   R . n 
C 3 1163 LEU 1163 1166 ?   ?   ?   R . n 
C 3 1164 GLY 1164 1167 ?   ?   ?   R . n 
C 3 1165 ASP 1165 1168 ?   ?   ?   R . n 
C 3 1166 ILE 1166 1169 ?   ?   ?   R . n 
C 3 1167 SER 1167 1170 ?   ?   ?   R . n 
C 3 1168 GLY 1168 1171 ?   ?   ?   R . n 
C 3 1169 ILE 1169 1172 ?   ?   ?   R . n 
C 3 1170 ASN 1170 1173 ?   ?   ?   R . n 
C 3 1171 ALA 1171 1174 ?   ?   ?   R . n 
C 3 1172 SER 1172 1175 ?   ?   ?   R . n 
C 3 1173 VAL 1173 1176 ?   ?   ?   R . n 
C 3 1174 VAL 1174 1177 ?   ?   ?   R . n 
C 3 1175 ASN 1175 1178 ?   ?   ?   R . n 
C 3 1176 ILE 1176 1179 ?   ?   ?   R . n 
C 3 1177 GLN 1177 1180 ?   ?   ?   R . n 
C 3 1178 LYS 1178 1181 ?   ?   ?   R . n 
C 3 1179 GLU 1179 1182 ?   ?   ?   R . n 
C 3 1180 ILE 1180 1183 ?   ?   ?   R . n 
C 3 1181 ASP 1181 1184 ?   ?   ?   R . n 
C 3 1182 ARG 1182 1185 ?   ?   ?   R . n 
C 3 1183 LEU 1183 1186 ?   ?   ?   R . n 
C 3 1184 ASN 1184 1187 ?   ?   ?   R . n 
C 3 1185 GLU 1185 1188 ?   ?   ?   R . n 
C 3 1186 VAL 1186 1189 ?   ?   ?   R . n 
C 3 1187 ALA 1187 1190 ?   ?   ?   R . n 
C 3 1188 LYS 1188 1191 ?   ?   ?   R . n 
C 3 1189 ASN 1189 1192 ?   ?   ?   R . n 
C 3 1190 LEU 1190 1193 ?   ?   ?   R . n 
C 3 1191 ASN 1191 1194 ?   ?   ?   R . n 
C 3 1192 GLU 1192 1195 ?   ?   ?   R . n 
C 3 1193 SER 1193 1196 ?   ?   ?   R . n 
C 3 1194 LEU 1194 1197 ?   ?   ?   R . n 
C 3 1195 ILE 1195 1198 ?   ?   ?   R . n 
C 3 1196 ASP 1196 1199 ?   ?   ?   R . n 
C 3 1197 LEU 1197 1200 ?   ?   ?   R . n 
C 3 1198 GLN 1198 1201 ?   ?   ?   R . n 
C 3 1199 GLU 1199 1202 ?   ?   ?   R . n 
C 3 1200 LEU 1200 1203 ?   ?   ?   R . n 
C 3 1201 GLY 1201 1204 ?   ?   ?   R . n 
C 3 1202 LYS 1202 1205 ?   ?   ?   R . n 
C 3 1203 TYR 1203 1206 ?   ?   ?   R . n 
C 3 1204 GLU 1204 1207 ?   ?   ?   R . n 
C 3 1205 GLN 1205 1208 ?   ?   ?   R . n 
C 3 1206 GLY 1206 1209 ?   ?   ?   R . n 
C 3 1207 SER 1207 1210 ?   ?   ?   R . n 
C 3 1208 GLY 1208 1211 ?   ?   ?   R . n 
C 3 1209 TYR 1209 1212 ?   ?   ?   R . n 
C 3 1210 ILE 1210 1213 ?   ?   ?   R . n 
C 3 1211 PRO 1211 1214 ?   ?   ?   R . n 
C 3 1212 GLU 1212 1215 ?   ?   ?   R . n 
C 3 1213 ALA 1213 1216 ?   ?   ?   R . n 
C 3 1214 PRO 1214 1217 ?   ?   ?   R . n 
C 3 1215 ARG 1215 1218 ?   ?   ?   R . n 
C 3 1216 ASP 1216 1219 ?   ?   ?   R . n 
C 3 1217 GLY 1217 1220 ?   ?   ?   R . n 
C 3 1218 GLN 1218 1221 ?   ?   ?   R . n 
C 3 1219 ALA 1219 1222 ?   ?   ?   R . n 
C 3 1220 TYR 1220 1223 ?   ?   ?   R . n 
C 3 1221 VAL 1221 1224 ?   ?   ?   R . n 
C 3 1222 ARG 1222 1225 ?   ?   ?   R . n 
C 3 1223 LYS 1223 1226 ?   ?   ?   R . n 
C 3 1224 ASP 1224 1227 ?   ?   ?   R . n 
C 3 1225 GLY 1225 1228 ?   ?   ?   R . n 
C 3 1226 GLU 1226 1229 ?   ?   ?   R . n 
C 3 1227 TRP 1227 1230 ?   ?   ?   R . n 
C 3 1228 VAL 1228 1231 ?   ?   ?   R . n 
C 3 1229 LEU 1229 1232 ?   ?   ?   R . n 
C 3 1230 LEU 1230 1233 ?   ?   ?   R . n 
C 3 1231 SER 1231 1234 ?   ?   ?   R . n 
C 3 1232 THR 1232 1235 ?   ?   ?   R . n 
C 3 1233 PHE 1233 1236 ?   ?   ?   R . n 
C 3 1234 LEU 1234 1237 ?   ?   ?   R . n 
C 3 1235 GLY 1235 1238 ?   ?   ?   R . n 
C 3 1236 ARG 1236 1239 ?   ?   ?   R . n 
C 3 1237 SER 1237 1240 ?   ?   ?   R . n 
C 3 1238 LEU 1238 1241 ?   ?   ?   R . n 
C 3 1239 GLU 1239 1242 ?   ?   ?   R . n 
C 3 1240 VAL 1240 1243 ?   ?   ?   R . n 
C 3 1241 LEU 1241 1244 ?   ?   ?   R . n 
C 3 1242 PHE 1242 1245 ?   ?   ?   R . n 
C 3 1243 GLN 1243 1246 ?   ?   ?   R . n 
C 3 1244 GLY 1244 1247 ?   ?   ?   R . n 
C 3 1245 PRO 1245 1248 ?   ?   ?   R . n 
C 3 1246 GLY 1246 1249 ?   ?   ?   R . n 
C 3 1247 HIS 1247 1250 ?   ?   ?   R . n 
C 3 1248 HIS 1248 1251 ?   ?   ?   R . n 
C 3 1249 HIS 1249 1252 ?   ?   ?   R . n 
C 3 1250 HIS 1250 1253 ?   ?   ?   R . n 
C 3 1251 HIS 1251 1254 ?   ?   ?   R . n 
C 3 1252 HIS 1252 1255 ?   ?   ?   R . n 
C 3 1253 HIS 1253 1256 ?   ?   ?   R . n 
C 3 1254 HIS 1254 1257 ?   ?   ?   R . n 
C 3 1255 SER 1255 1258 ?   ?   ?   R . n 
C 3 1256 ALA 1256 1259 ?   ?   ?   R . n 
C 3 1257 TRP 1257 1260 ?   ?   ?   R . n 
C 3 1258 SER 1258 1261 ?   ?   ?   R . n 
C 3 1259 HIS 1259 1262 ?   ?   ?   R . n 
C 3 1260 PRO 1260 1263 ?   ?   ?   R . n 
C 3 1261 GLN 1261 1264 ?   ?   ?   R . n 
C 3 1262 PHE 1262 1265 ?   ?   ?   R . n 
C 3 1263 GLU 1263 1266 ?   ?   ?   R . n 
C 3 1264 LYS 1264 1267 ?   ?   ?   R . n 
C 3 1265 GLY 1265 1268 ?   ?   ?   R . n 
C 3 1266 GLY 1266 1269 ?   ?   ?   R . n 
C 3 1267 GLY 1267 1270 ?   ?   ?   R . n 
C 3 1268 SER 1268 1271 ?   ?   ?   R . n 
C 3 1269 GLY 1269 1272 ?   ?   ?   R . n 
C 3 1270 GLY 1270 1273 ?   ?   ?   R . n 
C 3 1271 GLY 1271 1274 ?   ?   ?   R . n 
C 3 1272 GLY 1272 1275 ?   ?   ?   R . n 
C 3 1273 SER 1273 1276 ?   ?   ?   R . n 
C 3 1274 GLY 1274 1277 ?   ?   ?   R . n 
C 3 1275 GLY 1275 1278 ?   ?   ?   R . n 
C 3 1276 SER 1276 1279 ?   ?   ?   R . n 
C 3 1277 ALA 1277 1280 ?   ?   ?   R . n 
C 3 1278 TRP 1278 1281 ?   ?   ?   R . n 
C 3 1279 SER 1279 1282 ?   ?   ?   R . n 
C 3 1280 HIS 1280 1283 ?   ?   ?   R . n 
C 3 1281 PRO 1281 1284 ?   ?   ?   R . n 
C 3 1282 GLN 1282 1285 ?   ?   ?   R . n 
C 3 1283 PHE 1283 1286 ?   ?   ?   R . n 
C 3 1284 GLU 1284 1287 ?   ?   ?   R . n 
C 3 1285 LYS 1285 1288 ?   ?   ?   R . n 
D 4 1    MET 1    1    ?   ?   ?   N . n 
D 4 2    PHE 2    2    ?   ?   ?   N . n 
D 4 3    VAL 3    3    ?   ?   ?   N . n 
D 4 4    PHE 4    4    ?   ?   ?   N . n 
D 4 5    LEU 5    5    ?   ?   ?   N . n 
D 4 6    VAL 6    6    ?   ?   ?   N . n 
D 4 7    LEU 7    7    ?   ?   ?   N . n 
D 4 8    LEU 8    8    ?   ?   ?   N . n 
D 4 9    PRO 9    9    ?   ?   ?   N . n 
D 4 10   LEU 10   10   ?   ?   ?   N . n 
D 4 11   VAL 11   11   ?   ?   ?   N . n 
D 4 12   SER 12   12   ?   ?   ?   N . n 
D 4 13   SER 13   13   ?   ?   ?   N . n 
D 4 14   GLN 14   14   ?   ?   ?   N . n 
D 4 15   CYS 15   15   ?   ?   ?   N . n 
D 4 16   VAL 16   16   ?   ?   ?   N . n 
D 4 17   ASN 17   17   ?   ?   ?   N . n 
D 4 18   PHE 18   18   ?   ?   ?   N . n 
D 4 19   THR 19   19   ?   ?   ?   N . n 
D 4 20   THR 20   20   ?   ?   ?   N . n 
D 4 21   ARG 21   21   ?   ?   ?   N . n 
D 4 22   THR 22   22   ?   ?   ?   N . n 
D 4 23   GLN 23   23   ?   ?   ?   N . n 
D 4 24   LEU 24   24   ?   ?   ?   N . n 
D 4 25   PRO 25   25   ?   ?   ?   N . n 
D 4 26   PRO 26   26   ?   ?   ?   N . n 
D 4 27   ALA 27   27   ?   ?   ?   N . n 
D 4 28   TYR 28   28   28  TYR TYR N . n 
D 4 29   THR 29   29   29  THR THR N . n 
D 4 30   ASN 30   30   30  ASN ASN N . n 
D 4 31   SER 31   31   31  SER SER N . n 
D 4 32   PHE 32   32   32  PHE PHE N . n 
D 4 33   THR 33   33   33  THR THR N . n 
D 4 34   ARG 34   34   34  ARG ARG N . n 
D 4 35   GLY 35   35   35  GLY GLY N . n 
D 4 36   VAL 36   36   36  VAL VAL N . n 
D 4 37   TYR 37   37   37  TYR TYR N . n 
D 4 38   TYR 38   38   38  TYR TYR N . n 
D 4 39   PRO 39   39   39  PRO PRO N . n 
D 4 40   ASP 40   40   40  ASP ASP N . n 
D 4 41   LYS 41   41   41  LYS LYS N . n 
D 4 42   VAL 42   42   42  VAL VAL N . n 
D 4 43   PHE 43   43   43  PHE PHE N . n 
D 4 44   ARG 44   44   44  ARG ARG N . n 
D 4 45   SER 45   45   45  SER SER N . n 
D 4 46   SER 46   46   ?   ?   ?   N . n 
D 4 47   VAL 47   47   ?   ?   ?   N . n 
D 4 48   LEU 48   48   ?   ?   ?   N . n 
D 4 49   HIS 49   49   49  HIS HIS N . n 
D 4 50   SER 50   50   50  SER SER N . n 
D 4 51   THR 51   51   51  THR THR N . n 
D 4 52   GLN 52   52   52  GLN GLN N . n 
D 4 53   ASP 53   53   53  ASP ASP N . n 
D 4 54   LEU 54   54   54  LEU LEU N . n 
D 4 55   PHE 55   55   55  PHE PHE N . n 
D 4 56   LEU 56   56   56  LEU LEU N . n 
D 4 57   PRO 57   57   57  PRO PRO N . n 
D 4 58   PHE 58   58   58  PHE PHE N . n 
D 4 59   PHE 59   59   59  PHE PHE N . n 
D 4 60   SER 60   60   60  SER SER N . n 
D 4 61   ASN 61   61   61  ASN ASN N . n 
D 4 62   VAL 62   62   62  VAL VAL N . n 
D 4 63   THR 63   63   63  THR THR N . n 
D 4 64   TRP 64   64   64  TRP TRP N . n 
D 4 65   PHE 65   65   65  PHE PHE N . n 
D 4 66   HIS 66   66   66  HIS HIS N . n 
D 4 67   ALA 67   67   ?   ?   ?   N . n 
D 4 68   ILE 68   68   ?   ?   ?   N . n 
D 4 69   HIS 69   69   ?   ?   ?   N . n 
D 4 70   VAL 70   70   ?   ?   ?   N . n 
D 4 71   SER 71   71   ?   ?   ?   N . n 
D 4 72   GLY 72   72   ?   ?   ?   N . n 
D 4 73   THR 73   73   ?   ?   ?   N . n 
D 4 74   ASN 74   74   ?   ?   ?   N . n 
D 4 75   GLY 75   75   ?   ?   ?   N . n 
D 4 76   THR 76   76   ?   ?   ?   N . n 
D 4 77   LYS 77   77   ?   ?   ?   N . n 
D 4 78   ARG 78   78   ?   ?   ?   N . n 
D 4 79   PHE 79   79   ?   ?   ?   N . n 
D 4 80   ALA 80   80   ?   ?   ?   N . n 
D 4 81   ASN 81   81   81  ASN ASN N . n 
D 4 82   PRO 82   82   82  PRO PRO N . n 
D 4 83   VAL 83   83   83  VAL VAL N . n 
D 4 84   LEU 84   84   84  LEU LEU N . n 
D 4 85   PRO 85   85   85  PRO PRO N . n 
D 4 86   PHE 86   86   86  PHE PHE N . n 
D 4 87   ASN 87   87   87  ASN ASN N . n 
D 4 88   ASP 88   88   88  ASP ASP N . n 
D 4 89   GLY 89   89   89  GLY GLY N . n 
D 4 90   VAL 90   90   90  VAL VAL N . n 
D 4 91   TYR 91   91   91  TYR TYR N . n 
D 4 92   PHE 92   92   92  PHE PHE N . n 
D 4 93   ALA 93   93   93  ALA ALA N . n 
D 4 94   SER 94   94   94  SER SER N . n 
D 4 95   THR 95   95   95  THR THR N . n 
D 4 96   GLU 96   96   ?   ?   ?   N . n 
D 4 97   LYS 97   97   ?   ?   ?   N . n 
D 4 98   SER 98   98   ?   ?   ?   N . n 
D 4 99   ASN 99   99   ?   ?   ?   N . n 
D 4 100  ILE 100  100  ?   ?   ?   N . n 
D 4 101  ILE 101  101  ?   ?   ?   N . n 
D 4 102  ARG 102  102  102 ARG ARG N . n 
D 4 103  GLY 103  103  103 GLY GLY N . n 
D 4 104  TRP 104  104  104 TRP TRP N . n 
D 4 105  ILE 105  105  105 ILE ILE N . n 
D 4 106  PHE 106  106  106 PHE PHE N . n 
D 4 107  GLY 107  107  107 GLY GLY N . n 
D 4 108  THR 108  108  108 THR THR N . n 
D 4 109  THR 109  109  109 THR THR N . n 
D 4 110  LEU 110  110  110 LEU LEU N . n 
D 4 111  ASP 111  111  111 ASP ASP N . n 
D 4 112  SER 112  112  112 SER SER N . n 
D 4 113  LYS 113  113  113 LYS LYS N . n 
D 4 114  THR 114  114  114 THR THR N . n 
D 4 115  GLN 115  115  115 GLN GLN N . n 
D 4 116  SER 116  116  116 SER SER N . n 
D 4 117  LEU 117  117  117 LEU LEU N . n 
D 4 118  LEU 118  118  118 LEU LEU N . n 
D 4 119  ILE 119  119  119 ILE ILE N . n 
D 4 120  VAL 120  120  120 VAL VAL N . n 
D 4 121  ASN 121  121  121 ASN ASN N . n 
D 4 122  ASN 122  122  122 ASN ASN N . n 
D 4 123  ALA 123  123  123 ALA ALA N . n 
D 4 124  THR 124  124  124 THR THR N . n 
D 4 125  ASN 125  125  125 ASN ASN N . n 
D 4 126  VAL 126  126  126 VAL VAL N . n 
D 4 127  VAL 127  127  127 VAL VAL N . n 
D 4 128  ILE 128  128  128 ILE ILE N . n 
D 4 129  LYS 129  129  129 LYS LYS N . n 
D 4 130  VAL 130  130  130 VAL VAL N . n 
D 4 131  CYS 131  131  131 CYS CYS N . n 
D 4 132  GLU 132  132  132 GLU GLU N . n 
D 4 133  PHE 133  133  133 PHE PHE N . n 
D 4 134  GLN 134  134  134 GLN GLN N . n 
D 4 135  PHE 135  135  ?   ?   ?   N . n 
D 4 136  CYS 136  136  ?   ?   ?   N . n 
D 4 137  ASN 137  137  ?   ?   ?   N . n 
D 4 138  ASP 138  138  ?   ?   ?   N . n 
D 4 139  PRO 139  139  ?   ?   ?   N . n 
D 4 140  PHE 140  140  ?   ?   ?   N . n 
D 4 141  LEU 141  141  ?   ?   ?   N . n 
D 4 142  GLY 142  142  ?   ?   ?   N . n 
D 4 143  VAL 143  143  ?   ?   ?   N . n 
D 4 144  TYR 144  144  ?   ?   ?   N . n 
D 4 145  TYR 145  145  ?   ?   ?   N . n 
D 4 146  HIS 146  146  ?   ?   ?   N . n 
D 4 147  LYS 147  147  ?   ?   ?   N . n 
D 4 148  ASN 148  148  ?   ?   ?   N . n 
D 4 149  ASN 149  149  ?   ?   ?   N . n 
D 4 150  LYS 150  150  ?   ?   ?   N . n 
D 4 151  SER 151  151  ?   ?   ?   N . n 
D 4 152  TRP 152  152  ?   ?   ?   N . n 
D 4 153  MET 153  153  ?   ?   ?   N . n 
D 4 154  GLU 154  154  ?   ?   ?   N . n 
D 4 155  SER 155  155  ?   ?   ?   N . n 
D 4 156  GLU 156  156  ?   ?   ?   N . n 
D 4 157  PHE 157  157  ?   ?   ?   N . n 
D 4 158  ARG 158  158  ?   ?   ?   N . n 
D 4 159  VAL 159  159  ?   ?   ?   N . n 
D 4 160  TYR 160  160  160 TYR TYR N . n 
D 4 161  SER 161  161  161 SER SER N . n 
D 4 162  SER 162  162  162 SER SER N . n 
D 4 163  ALA 163  163  163 ALA ALA N . n 
D 4 164  ASN 164  164  164 ASN ASN N . n 
D 4 165  ASN 165  165  165 ASN ASN N . n 
D 4 166  CYS 166  166  166 CYS CYS N . n 
D 4 167  THR 167  167  167 THR THR N . n 
D 4 168  PHE 168  168  168 PHE PHE N . n 
D 4 169  GLU 169  169  169 GLU GLU N . n 
D 4 170  TYR 170  170  170 TYR TYR N . n 
D 4 171  VAL 171  171  171 VAL VAL N . n 
D 4 172  SER 172  172  172 SER SER N . n 
D 4 173  GLN 173  173  173 GLN GLN N . n 
D 4 174  PRO 174  174  174 PRO PRO N . n 
D 4 175  PHE 175  175  175 PHE PHE N . n 
D 4 176  LEU 176  176  ?   ?   ?   N . n 
D 4 177  MET 177  177  ?   ?   ?   N . n 
D 4 178  ASP 178  178  ?   ?   ?   N . n 
D 4 179  LEU 179  179  ?   ?   ?   N . n 
D 4 180  GLU 180  180  ?   ?   ?   N . n 
D 4 181  GLY 181  181  ?   ?   ?   N . n 
D 4 182  LYS 182  182  ?   ?   ?   N . n 
D 4 183  GLN 183  183  ?   ?   ?   N . n 
D 4 184  GLY 184  184  ?   ?   ?   N . n 
D 4 185  ASN 185  185  ?   ?   ?   N . n 
D 4 186  PHE 186  186  ?   ?   ?   N . n 
D 4 187  LYS 187  187  ?   ?   ?   N . n 
D 4 188  ASN 188  188  ?   ?   ?   N . n 
D 4 189  LEU 189  189  189 LEU LEU N . n 
D 4 190  ARG 190  190  190 ARG ARG N . n 
D 4 191  GLU 191  191  191 GLU GLU N . n 
D 4 192  PHE 192  192  192 PHE PHE N . n 
D 4 193  VAL 193  193  193 VAL VAL N . n 
D 4 194  PHE 194  194  194 PHE PHE N . n 
D 4 195  LYS 195  195  195 LYS LYS N . n 
D 4 196  ASN 196  196  196 ASN ASN N . n 
D 4 197  ILE 197  197  197 ILE ILE N . n 
D 4 198  ASP 198  198  198 ASP ASP N . n 
D 4 199  GLY 199  199  199 GLY GLY N . n 
D 4 200  TYR 200  200  200 TYR TYR N . n 
D 4 201  PHE 201  201  201 PHE PHE N . n 
D 4 202  LYS 202  202  202 LYS LYS N . n 
D 4 203  ILE 203  203  203 ILE ILE N . n 
D 4 204  TYR 204  204  204 TYR TYR N . n 
D 4 205  SER 205  205  205 SER SER N . n 
D 4 206  LYS 206  206  206 LYS LYS N . n 
D 4 207  HIS 207  207  ?   ?   ?   N . n 
D 4 208  THR 208  208  ?   ?   ?   N . n 
D 4 209  PRO 209  209  ?   ?   ?   N . n 
D 4 210  ILE 210  210  ?   ?   ?   N . n 
D 4 211  ASN 211  211  ?   ?   ?   N . n 
D 4 212  LEU 212  212  ?   ?   ?   N . n 
D 4 213  VAL 213  213  ?   ?   ?   N . n 
D 4 214  ARG 214  214  ?   ?   ?   N . n 
D 4 215  GLY 215  215  ?   ?   ?   N . n 
D 4 216  LEU 216  216  ?   ?   ?   N . n 
D 4 217  PRO 217  217  ?   ?   ?   N . n 
D 4 218  GLN 218  218  ?   ?   ?   N . n 
D 4 219  GLY 219  219  ?   ?   ?   N . n 
D 4 220  PHE 220  220  ?   ?   ?   N . n 
D 4 221  SER 221  221  221 SER SER N . n 
D 4 222  ALA 222  222  222 ALA ALA N . n 
D 4 223  LEU 223  223  223 LEU LEU N . n 
D 4 224  GLU 224  224  224 GLU GLU N . n 
D 4 225  PRO 225  225  225 PRO PRO N . n 
D 4 226  LEU 226  226  226 LEU LEU N . n 
D 4 227  VAL 227  227  227 VAL VAL N . n 
D 4 228  ASP 228  228  228 ASP ASP N . n 
D 4 229  LEU 229  229  229 LEU LEU N . n 
D 4 230  PRO 230  230  230 PRO PRO N . n 
D 4 231  ILE 231  231  231 ILE ILE N . n 
D 4 232  GLY 232  232  232 GLY GLY N . n 
D 4 233  ILE 233  233  233 ILE ILE N . n 
D 4 234  ASN 234  234  234 ASN ASN N . n 
D 4 235  ILE 235  235  235 ILE ILE N . n 
D 4 236  THR 236  236  236 THR THR N . n 
D 4 237  ARG 237  237  237 ARG ARG N . n 
D 4 238  PHE 238  238  238 PHE PHE N . n 
D 4 239  GLN 239  239  239 GLN GLN N . n 
D 4 240  THR 240  240  240 THR THR N . n 
D 4 241  LEU 241  241  241 LEU LEU N . n 
D 4 242  HIS 242  245  ?   ?   ?   N . n 
D 4 243  ARG 243  246  ?   ?   ?   N . n 
D 4 244  SER 244  247  ?   ?   ?   N . n 
D 4 245  TYR 245  248  ?   ?   ?   N . n 
D 4 246  LEU 246  249  ?   ?   ?   N . n 
D 4 247  THR 247  250  ?   ?   ?   N . n 
D 4 248  PRO 248  251  ?   ?   ?   N . n 
D 4 249  GLY 249  252  ?   ?   ?   N . n 
D 4 250  ASP 250  253  ?   ?   ?   N . n 
D 4 251  SER 251  254  ?   ?   ?   N . n 
D 4 252  SER 252  255  ?   ?   ?   N . n 
D 4 253  SER 253  256  ?   ?   ?   N . n 
D 4 254  GLY 254  257  ?   ?   ?   N . n 
D 4 255  TRP 255  258  ?   ?   ?   N . n 
D 4 256  THR 256  259  ?   ?   ?   N . n 
D 4 257  ALA 257  260  ?   ?   ?   N . n 
D 4 258  GLY 258  261  ?   ?   ?   N . n 
D 4 259  ALA 259  262  ?   ?   ?   N . n 
D 4 260  ALA 260  263  ?   ?   ?   N . n 
D 4 261  ALA 261  264  ?   ?   ?   N . n 
D 4 262  TYR 262  265  265 TYR TYR N . n 
D 4 263  TYR 263  266  266 TYR TYR N . n 
D 4 264  VAL 264  267  267 VAL VAL N . n 
D 4 265  GLY 265  268  268 GLY GLY N . n 
D 4 266  TYR 266  269  269 TYR TYR N . n 
D 4 267  LEU 267  270  270 LEU LEU N . n 
D 4 268  GLN 268  271  271 GLN GLN N . n 
D 4 269  PRO 269  272  272 PRO PRO N . n 
D 4 270  ARG 270  273  273 ARG ARG N . n 
D 4 271  THR 271  274  274 THR THR N . n 
D 4 272  PHE 272  275  275 PHE PHE N . n 
D 4 273  LEU 273  276  276 LEU LEU N . n 
D 4 274  LEU 274  277  277 LEU LEU N . n 
D 4 275  LYS 275  278  278 LYS LYS N . n 
D 4 276  TYR 276  279  279 TYR TYR N . n 
D 4 277  ASN 277  280  280 ASN ASN N . n 
D 4 278  GLU 278  281  281 GLU GLU N . n 
D 4 279  ASN 279  282  282 ASN ASN N . n 
D 4 280  GLY 280  283  283 GLY GLY N . n 
D 4 281  THR 281  284  284 THR THR N . n 
D 4 282  ILE 282  285  285 ILE ILE N . n 
D 4 283  THR 283  286  286 THR THR N . n 
D 4 284  ASP 284  287  287 ASP ASP N . n 
D 4 285  ALA 285  288  288 ALA ALA N . n 
D 4 286  VAL 286  289  289 VAL VAL N . n 
D 4 287  ASP 287  290  290 ASP ASP N . n 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5070  ? 
1 MORE         -9    ? 
1 'SSA (A^2)'  28710 ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2021-09-08 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.18.2_3874: 
_software.pdbx_ordinal           1 
# 
_pdbx_entry_details.entry_id                 7EY4 
_pdbx_entry_details.nonpolymer_details       ? 
_pdbx_entry_details.sequence_details         ? 
_pdbx_entry_details.compound_details         ? 
_pdbx_entry_details.source_details           ? 
_pdbx_entry_details.has_ligand_of_interest   Y 
# 
_em_3d_fitting.entry_id          7EY4 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7EY4 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               530214 
_em_3d_reconstruction.resolution                  3.69 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.2 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.details              ? 
_em_entity_assembly.name                 'Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-667' 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7EY4 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.mode                            'DARK FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             ? 
_em_imaging.nominal_defocus_min             ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7EY4 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7EY4 
_em_experiment.id                      1 
_em_experiment.aggregation_state       '3D ARRAY' 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OH 
_pdbx_validate_close_contact.auth_asym_id_1   N 
_pdbx_validate_close_contact.auth_comp_id_1   TYR 
_pdbx_validate_close_contact.auth_seq_id_1    37 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   N 
_pdbx_validate_close_contact.auth_comp_id_2   LEU 
_pdbx_validate_close_contact.auth_seq_id_2    54 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.15 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA H CYS 96  ? ? CB H CYS 96  ? ? SG H CYS 96  ? ? 121.36 114.20 7.16  1.10 N 
2 1 CA R CYS 379 ? ? CB R CYS 379 ? ? SG R CYS 379 ? ? 127.53 114.20 13.33 1.10 N 
3 1 CA R CYS 432 ? ? CB R CYS 432 ? ? SG R CYS 432 ? ? 127.18 114.20 12.98 1.10 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN L 6   ? ? -94.56  -63.09  
2  1 GLN L 27  ? ? -119.37 -169.75 
3  1 SER L 30  ? ? 76.13   -16.90  
4  1 ARG L 31  ? ? -151.30 1.52    
5  1 ALA L 51  ? ? 73.39   -8.06   
6  1 ALA L 55  ? ? -75.59  -168.86 
7  1 ASP L 82  ? ? -93.52  30.26   
8  1 ALA L 84  ? ? -149.07 -159.16 
9  1 TYR L 91  ? ? -141.11 46.59   
10 1 ASN L 92  ? ? -95.55  48.73   
11 1 PRO L 95  ? ? -76.61  -166.72 
12 1 PRO L 96  ? ? -35.22  132.50  
13 1 ILE H 48  ? ? -124.60 -53.69  
14 1 TYR H 50  ? ? -170.72 137.24  
15 1 PHE H 56  ? ? 35.82   45.53   
16 1 ALA H 57  ? ? -146.29 11.76   
17 1 ALA H 92  ? ? -166.99 -169.27 
18 1 ALA H 97  ? ? -79.76  -169.19 
19 1 ASN H 109 ? ? 27.13   73.98   
20 1 TYR H 110 ? ? -85.21  31.05   
21 1 ASP H 114 ? ? -141.79 47.09   
22 1 ASP H 117 ? ? -77.54  -157.69 
23 1 ILE H 118 ? ? -36.56  128.04  
24 1 ALA R 411 ? ? -172.52 149.37  
25 1 PRO N 39  ? ? -67.71  56.80   
26 1 ASN N 87  ? ? 58.05   -118.66 
27 1 ASN N 165 ? ? 71.87   -84.24  
28 1 CYS N 166 ? ? 54.27   81.75   
29 1 THR N 167 ? ? -84.00  -78.08  
30 1 GLU N 281 ? ? 65.57   -6.14   
31 1 ASN N 282 ? ? -140.24 43.62   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 SER L 7   ? ? PRO L 8   ? ? 132.41  
2 1 CYS R 379 ? ? TYR R 380 ? ? -140.32 
3 1 CYS R 432 ? ? VAL R 433 ? ? -144.68 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 H ASN 106 ? CG  ? B ASN 106 CG  
2 1 Y 1 H ASN 106 ? OD1 ? B ASN 106 OD1 
3 1 Y 1 H ASN 106 ? ND2 ? B ASN 106 ND2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 L ARG 109  ? A ARG 109  
2    1 Y 1 L THR 110  ? A THR 110  
3    1 Y 1 L VAL 111  ? A VAL 111  
4    1 Y 1 L ALA 112  ? A ALA 112  
5    1 Y 1 L ALA 113  ? A ALA 113  
6    1 Y 1 L PRO 114  ? A PRO 114  
7    1 Y 1 L SER 115  ? A SER 115  
8    1 Y 1 L VAL 116  ? A VAL 116  
9    1 Y 1 L PHE 117  ? A PHE 117  
10   1 Y 1 L ILE 118  ? A ILE 118  
11   1 Y 1 L PHE 119  ? A PHE 119  
12   1 Y 1 L PRO 120  ? A PRO 120  
13   1 Y 1 L PRO 121  ? A PRO 121  
14   1 Y 1 L SER 122  ? A SER 122  
15   1 Y 1 L ASP 123  ? A ASP 123  
16   1 Y 1 L GLU 124  ? A GLU 124  
17   1 Y 1 L GLN 125  ? A GLN 125  
18   1 Y 1 L LEU 126  ? A LEU 126  
19   1 Y 1 L LYS 127  ? A LYS 127  
20   1 Y 1 L SER 128  ? A SER 128  
21   1 Y 1 L GLY 129  ? A GLY 129  
22   1 Y 1 L THR 130  ? A THR 130  
23   1 Y 1 L ALA 131  ? A ALA 131  
24   1 Y 1 L SER 132  ? A SER 132  
25   1 Y 1 L VAL 133  ? A VAL 133  
26   1 Y 1 L VAL 134  ? A VAL 134  
27   1 Y 1 L CYS 135  ? A CYS 135  
28   1 Y 1 L LEU 136  ? A LEU 136  
29   1 Y 1 L LEU 137  ? A LEU 137  
30   1 Y 1 L ASN 138  ? A ASN 138  
31   1 Y 1 L ASN 139  ? A ASN 139  
32   1 Y 1 L PHE 140  ? A PHE 140  
33   1 Y 1 L TYR 141  ? A TYR 141  
34   1 Y 1 L PRO 142  ? A PRO 142  
35   1 Y 1 L ARG 143  ? A ARG 143  
36   1 Y 1 L GLU 144  ? A GLU 144  
37   1 Y 1 L ALA 145  ? A ALA 145  
38   1 Y 1 L LYS 146  ? A LYS 146  
39   1 Y 1 L VAL 147  ? A VAL 147  
40   1 Y 1 L GLN 148  ? A GLN 148  
41   1 Y 1 L TRP 149  ? A TRP 149  
42   1 Y 1 L LYS 150  ? A LYS 150  
43   1 Y 1 L VAL 151  ? A VAL 151  
44   1 Y 1 L ASP 152  ? A ASP 152  
45   1 Y 1 L ASN 153  ? A ASN 153  
46   1 Y 1 L ALA 154  ? A ALA 154  
47   1 Y 1 L LEU 155  ? A LEU 155  
48   1 Y 1 L GLN 156  ? A GLN 156  
49   1 Y 1 L SER 157  ? A SER 157  
50   1 Y 1 L GLY 158  ? A GLY 158  
51   1 Y 1 L ASN 159  ? A ASN 159  
52   1 Y 1 L SER 160  ? A SER 160  
53   1 Y 1 L GLN 161  ? A GLN 161  
54   1 Y 1 L GLU 162  ? A GLU 162  
55   1 Y 1 L SER 163  ? A SER 163  
56   1 Y 1 L VAL 164  ? A VAL 164  
57   1 Y 1 L THR 165  ? A THR 165  
58   1 Y 1 L GLU 166  ? A GLU 166  
59   1 Y 1 L GLN 167  ? A GLN 167  
60   1 Y 1 L ASP 168  ? A ASP 168  
61   1 Y 1 L SER 169  ? A SER 169  
62   1 Y 1 L LYS 170  ? A LYS 170  
63   1 Y 1 L ASP 171  ? A ASP 171  
64   1 Y 1 L SER 172  ? A SER 172  
65   1 Y 1 L THR 173  ? A THR 173  
66   1 Y 1 L TYR 174  ? A TYR 174  
67   1 Y 1 L SER 175  ? A SER 175  
68   1 Y 1 L LEU 176  ? A LEU 176  
69   1 Y 1 L SER 177  ? A SER 177  
70   1 Y 1 L SER 178  ? A SER 178  
71   1 Y 1 L THR 179  ? A THR 179  
72   1 Y 1 L LEU 180  ? A LEU 180  
73   1 Y 1 L THR 181  ? A THR 181  
74   1 Y 1 L LEU 182  ? A LEU 182  
75   1 Y 1 L SER 183  ? A SER 183  
76   1 Y 1 L LYS 184  ? A LYS 184  
77   1 Y 1 L ALA 185  ? A ALA 185  
78   1 Y 1 L ASP 186  ? A ASP 186  
79   1 Y 1 L TYR 187  ? A TYR 187  
80   1 Y 1 L GLU 188  ? A GLU 188  
81   1 Y 1 L LYS 189  ? A LYS 189  
82   1 Y 1 L HIS 190  ? A HIS 190  
83   1 Y 1 L LYS 191  ? A LYS 191  
84   1 Y 1 L VAL 192  ? A VAL 192  
85   1 Y 1 L TYR 193  ? A TYR 193  
86   1 Y 1 L ALA 194  ? A ALA 194  
87   1 Y 1 L CYS 195  ? A CYS 195  
88   1 Y 1 L GLU 196  ? A GLU 196  
89   1 Y 1 L VAL 197  ? A VAL 197  
90   1 Y 1 L THR 198  ? A THR 198  
91   1 Y 1 L HIS 199  ? A HIS 199  
92   1 Y 1 L GLN 200  ? A GLN 200  
93   1 Y 1 L GLY 201  ? A GLY 201  
94   1 Y 1 L LEU 202  ? A LEU 202  
95   1 Y 1 L SER 203  ? A SER 203  
96   1 Y 1 L SER 204  ? A SER 204  
97   1 Y 1 L PRO 205  ? A PRO 205  
98   1 Y 1 L VAL 206  ? A VAL 206  
99   1 Y 1 L THR 207  ? A THR 207  
100  1 Y 1 L LYS 208  ? A LYS 208  
101  1 Y 1 L SER 209  ? A SER 209  
102  1 Y 1 L PHE 210  ? A PHE 210  
103  1 Y 1 L ASN 211  ? A ASN 211  
104  1 Y 1 L ARG 212  ? A ARG 212  
105  1 Y 1 L GLY 213  ? A GLY 213  
106  1 Y 1 L GLU 214  ? A GLU 214  
107  1 Y 1 L CYS 215  ? A CYS 215  
108  1 Y 1 H GLN 1    ? B GLN 1    
109  1 Y 1 H SER 131  ? B SER 131  
110  1 Y 1 H THR 132  ? B THR 132  
111  1 Y 1 H LYS 133  ? B LYS 133  
112  1 Y 1 H GLY 134  ? B GLY 134  
113  1 Y 1 H PRO 135  ? B PRO 135  
114  1 Y 1 H SER 136  ? B SER 136  
115  1 Y 1 H VAL 137  ? B VAL 137  
116  1 Y 1 H PHE 138  ? B PHE 138  
117  1 Y 1 H PRO 139  ? B PRO 139  
118  1 Y 1 H LEU 140  ? B LEU 140  
119  1 Y 1 H ALA 141  ? B ALA 141  
120  1 Y 1 H PRO 142  ? B PRO 142  
121  1 Y 1 H SER 143  ? B SER 143  
122  1 Y 1 H SER 144  ? B SER 144  
123  1 Y 1 H LYS 145  ? B LYS 145  
124  1 Y 1 H SER 146  ? B SER 146  
125  1 Y 1 H THR 147  ? B THR 147  
126  1 Y 1 H SER 148  ? B SER 148  
127  1 Y 1 H GLY 149  ? B GLY 149  
128  1 Y 1 H GLY 150  ? B GLY 150  
129  1 Y 1 H THR 151  ? B THR 151  
130  1 Y 1 H ALA 152  ? B ALA 152  
131  1 Y 1 H ALA 153  ? B ALA 153  
132  1 Y 1 H LEU 154  ? B LEU 154  
133  1 Y 1 H GLY 155  ? B GLY 155  
134  1 Y 1 H CYS 156  ? B CYS 156  
135  1 Y 1 H LEU 157  ? B LEU 157  
136  1 Y 1 H VAL 158  ? B VAL 158  
137  1 Y 1 H LYS 159  ? B LYS 159  
138  1 Y 1 H ASP 160  ? B ASP 160  
139  1 Y 1 H TYR 161  ? B TYR 161  
140  1 Y 1 H PHE 162  ? B PHE 162  
141  1 Y 1 H PRO 163  ? B PRO 163  
142  1 Y 1 H GLU 164  ? B GLU 164  
143  1 Y 1 H PRO 165  ? B PRO 165  
144  1 Y 1 H VAL 166  ? B VAL 166  
145  1 Y 1 H THR 167  ? B THR 167  
146  1 Y 1 H VAL 168  ? B VAL 168  
147  1 Y 1 H SER 169  ? B SER 169  
148  1 Y 1 H TRP 170  ? B TRP 170  
149  1 Y 1 H ASN 171  ? B ASN 171  
150  1 Y 1 H SER 172  ? B SER 172  
151  1 Y 1 H GLY 173  ? B GLY 173  
152  1 Y 1 H ALA 174  ? B ALA 174  
153  1 Y 1 H LEU 175  ? B LEU 175  
154  1 Y 1 H THR 176  ? B THR 176  
155  1 Y 1 H SER 177  ? B SER 177  
156  1 Y 1 H GLY 178  ? B GLY 178  
157  1 Y 1 H VAL 179  ? B VAL 179  
158  1 Y 1 H HIS 180  ? B HIS 180  
159  1 Y 1 H THR 181  ? B THR 181  
160  1 Y 1 H PHE 182  ? B PHE 182  
161  1 Y 1 H PRO 183  ? B PRO 183  
162  1 Y 1 H ALA 184  ? B ALA 184  
163  1 Y 1 H VAL 185  ? B VAL 185  
164  1 Y 1 H LEU 186  ? B LEU 186  
165  1 Y 1 H GLN 187  ? B GLN 187  
166  1 Y 1 H SER 188  ? B SER 188  
167  1 Y 1 H SER 189  ? B SER 189  
168  1 Y 1 H GLY 190  ? B GLY 190  
169  1 Y 1 H LEU 191  ? B LEU 191  
170  1 Y 1 H TYR 192  ? B TYR 192  
171  1 Y 1 H SER 193  ? B SER 193  
172  1 Y 1 H LEU 194  ? B LEU 194  
173  1 Y 1 H SER 195  ? B SER 195  
174  1 Y 1 H SER 196  ? B SER 196  
175  1 Y 1 H VAL 197  ? B VAL 197  
176  1 Y 1 H VAL 198  ? B VAL 198  
177  1 Y 1 H THR 199  ? B THR 199  
178  1 Y 1 H VAL 200  ? B VAL 200  
179  1 Y 1 H PRO 201  ? B PRO 201  
180  1 Y 1 H SER 202  ? B SER 202  
181  1 Y 1 H SER 203  ? B SER 203  
182  1 Y 1 H SER 204  ? B SER 204  
183  1 Y 1 H LEU 205  ? B LEU 205  
184  1 Y 1 H GLY 206  ? B GLY 206  
185  1 Y 1 H THR 207  ? B THR 207  
186  1 Y 1 H GLN 208  ? B GLN 208  
187  1 Y 1 H THR 209  ? B THR 209  
188  1 Y 1 H TYR 210  ? B TYR 210  
189  1 Y 1 H ILE 211  ? B ILE 211  
190  1 Y 1 H CYS 212  ? B CYS 212  
191  1 Y 1 H ASN 213  ? B ASN 213  
192  1 Y 1 H VAL 214  ? B VAL 214  
193  1 Y 1 H ASN 215  ? B ASN 215  
194  1 Y 1 H HIS 216  ? B HIS 216  
195  1 Y 1 H LYS 217  ? B LYS 217  
196  1 Y 1 H PRO 218  ? B PRO 218  
197  1 Y 1 H SER 219  ? B SER 219  
198  1 Y 1 H ASN 220  ? B ASN 220  
199  1 Y 1 H THR 221  ? B THR 221  
200  1 Y 1 H LYS 222  ? B LYS 222  
201  1 Y 1 H VAL 223  ? B VAL 223  
202  1 Y 1 H ASP 224  ? B ASP 224  
203  1 Y 1 H LYS 225  ? B LYS 225  
204  1 Y 1 H LYS 226  ? B LYS 226  
205  1 Y 1 H VAL 227  ? B VAL 227  
206  1 Y 1 H GLU 228  ? B GLU 228  
207  1 Y 1 H PRO 229  ? B PRO 229  
208  1 Y 1 H LYS 230  ? B LYS 230  
209  1 Y 1 H SER 231  ? B SER 231  
210  1 Y 1 H CYS 232  ? B CYS 232  
211  1 Y 1 H ASP 233  ? B ASP 233  
212  1 Y 1 H LYS 234  ? B LYS 234  
213  1 Y 1 H HIS 235  ? B HIS 235  
214  1 Y 1 H HIS 236  ? B HIS 236  
215  1 Y 1 H HIS 237  ? B HIS 237  
216  1 Y 1 H HIS 238  ? B HIS 238  
217  1 Y 1 H HIS 239  ? B HIS 239  
218  1 Y 1 H HIS 240  ? B HIS 240  
219  1 Y 1 R MET 4    ? C MET 1    
220  1 Y 1 R PHE 5    ? C PHE 2    
221  1 Y 1 R VAL 6    ? C VAL 3    
222  1 Y 1 R PHE 7    ? C PHE 4    
223  1 Y 1 R LEU 8    ? C LEU 5    
224  1 Y 1 R VAL 9    ? C VAL 6    
225  1 Y 1 R LEU 10   ? C LEU 7    
226  1 Y 1 R LEU 11   ? C LEU 8    
227  1 Y 1 R PRO 12   ? C PRO 9    
228  1 Y 1 R LEU 13   ? C LEU 10   
229  1 Y 1 R VAL 14   ? C VAL 11   
230  1 Y 1 R SER 15   ? C SER 12   
231  1 Y 1 R SER 16   ? C SER 13   
232  1 Y 1 R GLN 17   ? C GLN 14   
233  1 Y 1 R CYS 18   ? C CYS 15   
234  1 Y 1 R VAL 19   ? C VAL 16   
235  1 Y 1 R ASN 20   ? C ASN 17   
236  1 Y 1 R PHE 21   ? C PHE 18   
237  1 Y 1 R THR 22   ? C THR 19   
238  1 Y 1 R THR 23   ? C THR 20   
239  1 Y 1 R ARG 24   ? C ARG 21   
240  1 Y 1 R THR 25   ? C THR 22   
241  1 Y 1 R GLN 26   ? C GLN 23   
242  1 Y 1 R LEU 27   ? C LEU 24   
243  1 Y 1 R PRO 28   ? C PRO 25   
244  1 Y 1 R PRO 29   ? C PRO 26   
245  1 Y 1 R ALA 30   ? C ALA 27   
246  1 Y 1 R TYR 31   ? C TYR 28   
247  1 Y 1 R THR 32   ? C THR 29   
248  1 Y 1 R ASN 33   ? C ASN 30   
249  1 Y 1 R SER 34   ? C SER 31   
250  1 Y 1 R PHE 35   ? C PHE 32   
251  1 Y 1 R THR 36   ? C THR 33   
252  1 Y 1 R ARG 37   ? C ARG 34   
253  1 Y 1 R GLY 38   ? C GLY 35   
254  1 Y 1 R VAL 39   ? C VAL 36   
255  1 Y 1 R TYR 40   ? C TYR 37   
256  1 Y 1 R TYR 41   ? C TYR 38   
257  1 Y 1 R PRO 42   ? C PRO 39   
258  1 Y 1 R ASP 43   ? C ASP 40   
259  1 Y 1 R LYS 44   ? C LYS 41   
260  1 Y 1 R VAL 45   ? C VAL 42   
261  1 Y 1 R PHE 46   ? C PHE 43   
262  1 Y 1 R ARG 47   ? C ARG 44   
263  1 Y 1 R SER 48   ? C SER 45   
264  1 Y 1 R SER 49   ? C SER 46   
265  1 Y 1 R VAL 50   ? C VAL 47   
266  1 Y 1 R LEU 51   ? C LEU 48   
267  1 Y 1 R HIS 52   ? C HIS 49   
268  1 Y 1 R SER 53   ? C SER 50   
269  1 Y 1 R THR 54   ? C THR 51   
270  1 Y 1 R GLN 55   ? C GLN 52   
271  1 Y 1 R ASP 56   ? C ASP 53   
272  1 Y 1 R LEU 57   ? C LEU 54   
273  1 Y 1 R PHE 58   ? C PHE 55   
274  1 Y 1 R LEU 59   ? C LEU 56   
275  1 Y 1 R PRO 60   ? C PRO 57   
276  1 Y 1 R PHE 61   ? C PHE 58   
277  1 Y 1 R PHE 62   ? C PHE 59   
278  1 Y 1 R SER 63   ? C SER 60   
279  1 Y 1 R ASN 64   ? C ASN 61   
280  1 Y 1 R VAL 65   ? C VAL 62   
281  1 Y 1 R THR 66   ? C THR 63   
282  1 Y 1 R TRP 67   ? C TRP 64   
283  1 Y 1 R PHE 68   ? C PHE 65   
284  1 Y 1 R HIS 69   ? C HIS 66   
285  1 Y 1 R ALA 70   ? C ALA 67   
286  1 Y 1 R ILE 71   ? C ILE 68   
287  1 Y 1 R HIS 72   ? C HIS 69   
288  1 Y 1 R VAL 73   ? C VAL 70   
289  1 Y 1 R SER 74   ? C SER 71   
290  1 Y 1 R GLY 75   ? C GLY 72   
291  1 Y 1 R THR 76   ? C THR 73   
292  1 Y 1 R ASN 77   ? C ASN 74   
293  1 Y 1 R GLY 78   ? C GLY 75   
294  1 Y 1 R THR 79   ? C THR 76   
295  1 Y 1 R LYS 80   ? C LYS 77   
296  1 Y 1 R ARG 81   ? C ARG 78   
297  1 Y 1 R PHE 82   ? C PHE 79   
298  1 Y 1 R ALA 83   ? C ALA 80   
299  1 Y 1 R ASN 84   ? C ASN 81   
300  1 Y 1 R PRO 85   ? C PRO 82   
301  1 Y 1 R VAL 86   ? C VAL 83   
302  1 Y 1 R LEU 87   ? C LEU 84   
303  1 Y 1 R PRO 88   ? C PRO 85   
304  1 Y 1 R PHE 89   ? C PHE 86   
305  1 Y 1 R ASN 90   ? C ASN 87   
306  1 Y 1 R ASP 91   ? C ASP 88   
307  1 Y 1 R GLY 92   ? C GLY 89   
308  1 Y 1 R VAL 93   ? C VAL 90   
309  1 Y 1 R TYR 94   ? C TYR 91   
310  1 Y 1 R PHE 95   ? C PHE 92   
311  1 Y 1 R ALA 96   ? C ALA 93   
312  1 Y 1 R SER 97   ? C SER 94   
313  1 Y 1 R THR 98   ? C THR 95   
314  1 Y 1 R GLU 99   ? C GLU 96   
315  1 Y 1 R LYS 100  ? C LYS 97   
316  1 Y 1 R SER 101  ? C SER 98   
317  1 Y 1 R ASN 102  ? C ASN 99   
318  1 Y 1 R ILE 103  ? C ILE 100  
319  1 Y 1 R ILE 104  ? C ILE 101  
320  1 Y 1 R ARG 105  ? C ARG 102  
321  1 Y 1 R GLY 106  ? C GLY 103  
322  1 Y 1 R TRP 107  ? C TRP 104  
323  1 Y 1 R ILE 108  ? C ILE 105  
324  1 Y 1 R PHE 109  ? C PHE 106  
325  1 Y 1 R GLY 110  ? C GLY 107  
326  1 Y 1 R THR 111  ? C THR 108  
327  1 Y 1 R THR 112  ? C THR 109  
328  1 Y 1 R LEU 113  ? C LEU 110  
329  1 Y 1 R ASP 114  ? C ASP 111  
330  1 Y 1 R SER 115  ? C SER 112  
331  1 Y 1 R LYS 116  ? C LYS 113  
332  1 Y 1 R THR 117  ? C THR 114  
333  1 Y 1 R GLN 118  ? C GLN 115  
334  1 Y 1 R SER 119  ? C SER 116  
335  1 Y 1 R LEU 120  ? C LEU 117  
336  1 Y 1 R LEU 121  ? C LEU 118  
337  1 Y 1 R ILE 122  ? C ILE 119  
338  1 Y 1 R VAL 123  ? C VAL 120  
339  1 Y 1 R ASN 124  ? C ASN 121  
340  1 Y 1 R ASN 125  ? C ASN 122  
341  1 Y 1 R ALA 126  ? C ALA 123  
342  1 Y 1 R THR 127  ? C THR 124  
343  1 Y 1 R ASN 128  ? C ASN 125  
344  1 Y 1 R VAL 129  ? C VAL 126  
345  1 Y 1 R VAL 130  ? C VAL 127  
346  1 Y 1 R ILE 131  ? C ILE 128  
347  1 Y 1 R LYS 132  ? C LYS 129  
348  1 Y 1 R VAL 133  ? C VAL 130  
349  1 Y 1 R CYS 134  ? C CYS 131  
350  1 Y 1 R GLU 135  ? C GLU 132  
351  1 Y 1 R PHE 136  ? C PHE 133  
352  1 Y 1 R GLN 137  ? C GLN 134  
353  1 Y 1 R PHE 138  ? C PHE 135  
354  1 Y 1 R CYS 139  ? C CYS 136  
355  1 Y 1 R ASN 140  ? C ASN 137  
356  1 Y 1 R ASP 141  ? C ASP 138  
357  1 Y 1 R PRO 142  ? C PRO 139  
358  1 Y 1 R PHE 143  ? C PHE 140  
359  1 Y 1 R LEU 144  ? C LEU 141  
360  1 Y 1 R GLY 145  ? C GLY 142  
361  1 Y 1 R VAL 146  ? C VAL 143  
362  1 Y 1 R TYR 147  ? C TYR 144  
363  1 Y 1 R TYR 148  ? C TYR 145  
364  1 Y 1 R HIS 149  ? C HIS 146  
365  1 Y 1 R LYS 150  ? C LYS 147  
366  1 Y 1 R ASN 151  ? C ASN 148  
367  1 Y 1 R ASN 152  ? C ASN 149  
368  1 Y 1 R LYS 153  ? C LYS 150  
369  1 Y 1 R SER 154  ? C SER 151  
370  1 Y 1 R TRP 155  ? C TRP 152  
371  1 Y 1 R MET 156  ? C MET 153  
372  1 Y 1 R GLU 157  ? C GLU 154  
373  1 Y 1 R SER 158  ? C SER 155  
374  1 Y 1 R GLU 159  ? C GLU 156  
375  1 Y 1 R PHE 160  ? C PHE 157  
376  1 Y 1 R ARG 161  ? C ARG 158  
377  1 Y 1 R VAL 162  ? C VAL 159  
378  1 Y 1 R TYR 163  ? C TYR 160  
379  1 Y 1 R SER 164  ? C SER 161  
380  1 Y 1 R SER 165  ? C SER 162  
381  1 Y 1 R ALA 166  ? C ALA 163  
382  1 Y 1 R ASN 167  ? C ASN 164  
383  1 Y 1 R ASN 168  ? C ASN 165  
384  1 Y 1 R CYS 169  ? C CYS 166  
385  1 Y 1 R THR 170  ? C THR 167  
386  1 Y 1 R PHE 171  ? C PHE 168  
387  1 Y 1 R GLU 172  ? C GLU 169  
388  1 Y 1 R TYR 173  ? C TYR 170  
389  1 Y 1 R VAL 174  ? C VAL 171  
390  1 Y 1 R SER 175  ? C SER 172  
391  1 Y 1 R GLN 176  ? C GLN 173  
392  1 Y 1 R PRO 177  ? C PRO 174  
393  1 Y 1 R PHE 178  ? C PHE 175  
394  1 Y 1 R LEU 179  ? C LEU 176  
395  1 Y 1 R MET 180  ? C MET 177  
396  1 Y 1 R ASP 181  ? C ASP 178  
397  1 Y 1 R LEU 182  ? C LEU 179  
398  1 Y 1 R GLU 183  ? C GLU 180  
399  1 Y 1 R GLY 184  ? C GLY 181  
400  1 Y 1 R LYS 185  ? C LYS 182  
401  1 Y 1 R GLN 186  ? C GLN 183  
402  1 Y 1 R GLY 187  ? C GLY 184  
403  1 Y 1 R ASN 188  ? C ASN 185  
404  1 Y 1 R PHE 189  ? C PHE 186  
405  1 Y 1 R LYS 190  ? C LYS 187  
406  1 Y 1 R ASN 191  ? C ASN 188  
407  1 Y 1 R LEU 192  ? C LEU 189  
408  1 Y 1 R ARG 193  ? C ARG 190  
409  1 Y 1 R GLU 194  ? C GLU 191  
410  1 Y 1 R PHE 195  ? C PHE 192  
411  1 Y 1 R VAL 196  ? C VAL 193  
412  1 Y 1 R PHE 197  ? C PHE 194  
413  1 Y 1 R LYS 198  ? C LYS 195  
414  1 Y 1 R ASN 199  ? C ASN 196  
415  1 Y 1 R ILE 200  ? C ILE 197  
416  1 Y 1 R ASP 201  ? C ASP 198  
417  1 Y 1 R GLY 202  ? C GLY 199  
418  1 Y 1 R TYR 203  ? C TYR 200  
419  1 Y 1 R PHE 204  ? C PHE 201  
420  1 Y 1 R LYS 205  ? C LYS 202  
421  1 Y 1 R ILE 206  ? C ILE 203  
422  1 Y 1 R TYR 207  ? C TYR 204  
423  1 Y 1 R SER 208  ? C SER 205  
424  1 Y 1 R LYS 209  ? C LYS 206  
425  1 Y 1 R HIS 210  ? C HIS 207  
426  1 Y 1 R THR 211  ? C THR 208  
427  1 Y 1 R PRO 212  ? C PRO 209  
428  1 Y 1 R ILE 213  ? C ILE 210  
429  1 Y 1 R ASN 214  ? C ASN 211  
430  1 Y 1 R LEU 215  ? C LEU 212  
431  1 Y 1 R VAL 216  ? C VAL 213  
432  1 Y 1 R ARG 217  ? C ARG 214  
433  1 Y 1 R GLY 218  ? C GLY 215  
434  1 Y 1 R LEU 219  ? C LEU 216  
435  1 Y 1 R PRO 220  ? C PRO 217  
436  1 Y 1 R GLN 221  ? C GLN 218  
437  1 Y 1 R GLY 222  ? C GLY 219  
438  1 Y 1 R PHE 223  ? C PHE 220  
439  1 Y 1 R SER 224  ? C SER 221  
440  1 Y 1 R ALA 225  ? C ALA 222  
441  1 Y 1 R LEU 226  ? C LEU 223  
442  1 Y 1 R GLU 227  ? C GLU 224  
443  1 Y 1 R PRO 228  ? C PRO 225  
444  1 Y 1 R LEU 229  ? C LEU 226  
445  1 Y 1 R VAL 230  ? C VAL 227  
446  1 Y 1 R ASP 231  ? C ASP 228  
447  1 Y 1 R LEU 232  ? C LEU 229  
448  1 Y 1 R PRO 233  ? C PRO 230  
449  1 Y 1 R ILE 234  ? C ILE 231  
450  1 Y 1 R GLY 235  ? C GLY 232  
451  1 Y 1 R ILE 236  ? C ILE 233  
452  1 Y 1 R ASN 237  ? C ASN 234  
453  1 Y 1 R ILE 238  ? C ILE 235  
454  1 Y 1 R THR 239  ? C THR 236  
455  1 Y 1 R ARG 240  ? C ARG 237  
456  1 Y 1 R PHE 241  ? C PHE 238  
457  1 Y 1 R GLN 242  ? C GLN 239  
458  1 Y 1 R THR 243  ? C THR 240  
459  1 Y 1 R LEU 244  ? C LEU 241  
460  1 Y 1 R HIS 245  ? C HIS 242  
461  1 Y 1 R ARG 246  ? C ARG 243  
462  1 Y 1 R SER 247  ? C SER 244  
463  1 Y 1 R TYR 248  ? C TYR 245  
464  1 Y 1 R LEU 249  ? C LEU 246  
465  1 Y 1 R THR 250  ? C THR 247  
466  1 Y 1 R PRO 251  ? C PRO 248  
467  1 Y 1 R GLY 252  ? C GLY 249  
468  1 Y 1 R ASP 253  ? C ASP 250  
469  1 Y 1 R SER 254  ? C SER 251  
470  1 Y 1 R SER 255  ? C SER 252  
471  1 Y 1 R SER 256  ? C SER 253  
472  1 Y 1 R GLY 257  ? C GLY 254  
473  1 Y 1 R TRP 258  ? C TRP 255  
474  1 Y 1 R THR 259  ? C THR 256  
475  1 Y 1 R ALA 260  ? C ALA 257  
476  1 Y 1 R GLY 261  ? C GLY 258  
477  1 Y 1 R ALA 262  ? C ALA 259  
478  1 Y 1 R ALA 263  ? C ALA 260  
479  1 Y 1 R ALA 264  ? C ALA 261  
480  1 Y 1 R TYR 265  ? C TYR 262  
481  1 Y 1 R TYR 266  ? C TYR 263  
482  1 Y 1 R VAL 267  ? C VAL 264  
483  1 Y 1 R GLY 268  ? C GLY 265  
484  1 Y 1 R TYR 269  ? C TYR 266  
485  1 Y 1 R LEU 270  ? C LEU 267  
486  1 Y 1 R GLN 271  ? C GLN 268  
487  1 Y 1 R PRO 272  ? C PRO 269  
488  1 Y 1 R ARG 273  ? C ARG 270  
489  1 Y 1 R THR 274  ? C THR 271  
490  1 Y 1 R PHE 275  ? C PHE 272  
491  1 Y 1 R LEU 276  ? C LEU 273  
492  1 Y 1 R LEU 277  ? C LEU 274  
493  1 Y 1 R LYS 278  ? C LYS 275  
494  1 Y 1 R TYR 279  ? C TYR 276  
495  1 Y 1 R ASN 280  ? C ASN 277  
496  1 Y 1 R GLU 281  ? C GLU 278  
497  1 Y 1 R ASN 282  ? C ASN 279  
498  1 Y 1 R GLY 283  ? C GLY 280  
499  1 Y 1 R THR 284  ? C THR 281  
500  1 Y 1 R ILE 285  ? C ILE 282  
501  1 Y 1 R THR 286  ? C THR 283  
502  1 Y 1 R ASP 287  ? C ASP 284  
503  1 Y 1 R ALA 288  ? C ALA 285  
504  1 Y 1 R VAL 289  ? C VAL 286  
505  1 Y 1 R ASP 290  ? C ASP 287  
506  1 Y 1 R CYS 291  ? C CYS 288  
507  1 Y 1 R ALA 292  ? C ALA 289  
508  1 Y 1 R LEU 293  ? C LEU 290  
509  1 Y 1 R ASP 294  ? C ASP 291  
510  1 Y 1 R PRO 295  ? C PRO 292  
511  1 Y 1 R LEU 296  ? C LEU 293  
512  1 Y 1 R SER 297  ? C SER 294  
513  1 Y 1 R GLU 298  ? C GLU 295  
514  1 Y 1 R THR 299  ? C THR 296  
515  1 Y 1 R LYS 300  ? C LYS 297  
516  1 Y 1 R CYS 301  ? C CYS 298  
517  1 Y 1 R THR 302  ? C THR 299  
518  1 Y 1 R LEU 303  ? C LEU 300  
519  1 Y 1 R LYS 304  ? C LYS 301  
520  1 Y 1 R SER 305  ? C SER 302  
521  1 Y 1 R PHE 306  ? C PHE 303  
522  1 Y 1 R THR 307  ? C THR 304  
523  1 Y 1 R VAL 308  ? C VAL 305  
524  1 Y 1 R GLU 309  ? C GLU 306  
525  1 Y 1 R LYS 310  ? C LYS 307  
526  1 Y 1 R GLY 311  ? C GLY 308  
527  1 Y 1 R ILE 312  ? C ILE 309  
528  1 Y 1 R TYR 313  ? C TYR 310  
529  1 Y 1 R GLN 314  ? C GLN 311  
530  1 Y 1 R THR 315  ? C THR 312  
531  1 Y 1 R SER 316  ? C SER 313  
532  1 Y 1 R ASN 317  ? C ASN 314  
533  1 Y 1 R PHE 318  ? C PHE 315  
534  1 Y 1 R ARG 319  ? C ARG 316  
535  1 Y 1 R VAL 320  ? C VAL 317  
536  1 Y 1 R GLN 321  ? C GLN 318  
537  1 Y 1 R PRO 322  ? C PRO 319  
538  1 Y 1 R THR 323  ? C THR 320  
539  1 Y 1 R GLU 324  ? C GLU 321  
540  1 Y 1 R SER 325  ? C SER 322  
541  1 Y 1 R ILE 326  ? C ILE 323  
542  1 Y 1 R VAL 327  ? C VAL 324  
543  1 Y 1 R ARG 328  ? C ARG 325  
544  1 Y 1 R PHE 329  ? C PHE 326  
545  1 Y 1 R PRO 330  ? C PRO 327  
546  1 Y 1 R ASN 331  ? C ASN 328  
547  1 Y 1 R ILE 332  ? C ILE 329  
548  1 Y 1 R THR 333  ? C THR 330  
549  1 Y 1 R LEU 517  ? C LEU 514  
550  1 Y 1 R LEU 518  ? C LEU 515  
551  1 Y 1 R HIS 519  ? C HIS 516  
552  1 Y 1 R ALA 520  ? C ALA 517  
553  1 Y 1 R PRO 521  ? C PRO 518  
554  1 Y 1 R ALA 522  ? C ALA 519  
555  1 Y 1 R THR 523  ? C THR 520  
556  1 Y 1 R VAL 524  ? C VAL 521  
557  1 Y 1 R CYS 525  ? C CYS 522  
558  1 Y 1 R GLY 526  ? C GLY 523  
559  1 Y 1 R PRO 527  ? C PRO 524  
560  1 Y 1 R LYS 528  ? C LYS 525  
561  1 Y 1 R LYS 529  ? C LYS 526  
562  1 Y 1 R SER 530  ? C SER 527  
563  1 Y 1 R THR 531  ? C THR 528  
564  1 Y 1 R ASN 532  ? C ASN 529  
565  1 Y 1 R LEU 533  ? C LEU 530  
566  1 Y 1 R VAL 534  ? C VAL 531  
567  1 Y 1 R LYS 535  ? C LYS 532  
568  1 Y 1 R ASN 536  ? C ASN 533  
569  1 Y 1 R LYS 537  ? C LYS 534  
570  1 Y 1 R CYS 538  ? C CYS 535  
571  1 Y 1 R VAL 539  ? C VAL 536  
572  1 Y 1 R ASN 540  ? C ASN 537  
573  1 Y 1 R PHE 541  ? C PHE 538  
574  1 Y 1 R ASN 542  ? C ASN 539  
575  1 Y 1 R PHE 543  ? C PHE 540  
576  1 Y 1 R ASN 544  ? C ASN 541  
577  1 Y 1 R GLY 545  ? C GLY 542  
578  1 Y 1 R LEU 546  ? C LEU 543  
579  1 Y 1 R THR 547  ? C THR 544  
580  1 Y 1 R GLY 548  ? C GLY 545  
581  1 Y 1 R THR 549  ? C THR 546  
582  1 Y 1 R GLY 550  ? C GLY 547  
583  1 Y 1 R VAL 551  ? C VAL 548  
584  1 Y 1 R LEU 552  ? C LEU 549  
585  1 Y 1 R THR 553  ? C THR 550  
586  1 Y 1 R GLU 554  ? C GLU 551  
587  1 Y 1 R SER 555  ? C SER 552  
588  1 Y 1 R ASN 556  ? C ASN 553  
589  1 Y 1 R LYS 557  ? C LYS 554  
590  1 Y 1 R LYS 558  ? C LYS 555  
591  1 Y 1 R PHE 559  ? C PHE 556  
592  1 Y 1 R LEU 560  ? C LEU 557  
593  1 Y 1 R PRO 561  ? C PRO 558  
594  1 Y 1 R PHE 562  ? C PHE 559  
595  1 Y 1 R GLN 563  ? C GLN 560  
596  1 Y 1 R GLN 564  ? C GLN 561  
597  1 Y 1 R PHE 565  ? C PHE 562  
598  1 Y 1 R GLY 566  ? C GLY 563  
599  1 Y 1 R ARG 567  ? C ARG 564  
600  1 Y 1 R ASP 568  ? C ASP 565  
601  1 Y 1 R ILE 569  ? C ILE 566  
602  1 Y 1 R ALA 570  ? C ALA 567  
603  1 Y 1 R ASP 571  ? C ASP 568  
604  1 Y 1 R THR 572  ? C THR 569  
605  1 Y 1 R THR 573  ? C THR 570  
606  1 Y 1 R ASP 574  ? C ASP 571  
607  1 Y 1 R ALA 575  ? C ALA 572  
608  1 Y 1 R VAL 576  ? C VAL 573  
609  1 Y 1 R ARG 577  ? C ARG 574  
610  1 Y 1 R ASP 578  ? C ASP 575  
611  1 Y 1 R PRO 579  ? C PRO 576  
612  1 Y 1 R GLN 580  ? C GLN 577  
613  1 Y 1 R THR 581  ? C THR 578  
614  1 Y 1 R LEU 582  ? C LEU 579  
615  1 Y 1 R GLU 583  ? C GLU 580  
616  1 Y 1 R ILE 584  ? C ILE 581  
617  1 Y 1 R LEU 585  ? C LEU 582  
618  1 Y 1 R ASP 586  ? C ASP 583  
619  1 Y 1 R ILE 587  ? C ILE 584  
620  1 Y 1 R THR 588  ? C THR 585  
621  1 Y 1 R PRO 589  ? C PRO 586  
622  1 Y 1 R CYS 590  ? C CYS 587  
623  1 Y 1 R SER 591  ? C SER 588  
624  1 Y 1 R PHE 592  ? C PHE 589  
625  1 Y 1 R GLY 593  ? C GLY 590  
626  1 Y 1 R GLY 594  ? C GLY 591  
627  1 Y 1 R VAL 595  ? C VAL 592  
628  1 Y 1 R SER 596  ? C SER 593  
629  1 Y 1 R VAL 597  ? C VAL 594  
630  1 Y 1 R ILE 598  ? C ILE 595  
631  1 Y 1 R THR 599  ? C THR 596  
632  1 Y 1 R PRO 600  ? C PRO 597  
633  1 Y 1 R GLY 601  ? C GLY 598  
634  1 Y 1 R THR 602  ? C THR 599  
635  1 Y 1 R ASN 603  ? C ASN 600  
636  1 Y 1 R THR 604  ? C THR 601  
637  1 Y 1 R SER 605  ? C SER 602  
638  1 Y 1 R ASN 606  ? C ASN 603  
639  1 Y 1 R GLN 607  ? C GLN 604  
640  1 Y 1 R VAL 608  ? C VAL 605  
641  1 Y 1 R ALA 609  ? C ALA 606  
642  1 Y 1 R VAL 610  ? C VAL 607  
643  1 Y 1 R LEU 611  ? C LEU 608  
644  1 Y 1 R TYR 612  ? C TYR 609  
645  1 Y 1 R GLN 613  ? C GLN 610  
646  1 Y 1 R GLY 614  ? C GLY 611  
647  1 Y 1 R VAL 615  ? C VAL 612  
648  1 Y 1 R ASN 616  ? C ASN 613  
649  1 Y 1 R CYS 617  ? C CYS 614  
650  1 Y 1 R THR 618  ? C THR 615  
651  1 Y 1 R GLU 619  ? C GLU 616  
652  1 Y 1 R VAL 620  ? C VAL 617  
653  1 Y 1 R PRO 621  ? C PRO 618  
654  1 Y 1 R VAL 622  ? C VAL 619  
655  1 Y 1 R ALA 623  ? C ALA 620  
656  1 Y 1 R ILE 624  ? C ILE 621  
657  1 Y 1 R HIS 625  ? C HIS 622  
658  1 Y 1 R ALA 626  ? C ALA 623  
659  1 Y 1 R ASP 627  ? C ASP 624  
660  1 Y 1 R GLN 628  ? C GLN 625  
661  1 Y 1 R LEU 629  ? C LEU 626  
662  1 Y 1 R THR 630  ? C THR 627  
663  1 Y 1 R PRO 631  ? C PRO 628  
664  1 Y 1 R THR 632  ? C THR 629  
665  1 Y 1 R TRP 633  ? C TRP 630  
666  1 Y 1 R ARG 634  ? C ARG 631  
667  1 Y 1 R VAL 635  ? C VAL 632  
668  1 Y 1 R TYR 636  ? C TYR 633  
669  1 Y 1 R SER 637  ? C SER 634  
670  1 Y 1 R THR 638  ? C THR 635  
671  1 Y 1 R GLY 639  ? C GLY 636  
672  1 Y 1 R SER 640  ? C SER 637  
673  1 Y 1 R ASN 641  ? C ASN 638  
674  1 Y 1 R VAL 642  ? C VAL 639  
675  1 Y 1 R PHE 643  ? C PHE 640  
676  1 Y 1 R GLN 644  ? C GLN 641  
677  1 Y 1 R THR 645  ? C THR 642  
678  1 Y 1 R ARG 646  ? C ARG 643  
679  1 Y 1 R ALA 647  ? C ALA 644  
680  1 Y 1 R GLY 648  ? C GLY 645  
681  1 Y 1 R CYS 649  ? C CYS 646  
682  1 Y 1 R LEU 650  ? C LEU 647  
683  1 Y 1 R ILE 651  ? C ILE 648  
684  1 Y 1 R GLY 652  ? C GLY 649  
685  1 Y 1 R ALA 653  ? C ALA 650  
686  1 Y 1 R GLU 654  ? C GLU 651  
687  1 Y 1 R HIS 655  ? C HIS 652  
688  1 Y 1 R VAL 656  ? C VAL 653  
689  1 Y 1 R ASN 657  ? C ASN 654  
690  1 Y 1 R ASN 658  ? C ASN 655  
691  1 Y 1 R SER 659  ? C SER 656  
692  1 Y 1 R TYR 660  ? C TYR 657  
693  1 Y 1 R GLU 661  ? C GLU 658  
694  1 Y 1 R CYS 662  ? C CYS 659  
695  1 Y 1 R ASP 663  ? C ASP 660  
696  1 Y 1 R ILE 664  ? C ILE 661  
697  1 Y 1 R PRO 665  ? C PRO 662  
698  1 Y 1 R ILE 666  ? C ILE 663  
699  1 Y 1 R GLY 667  ? C GLY 664  
700  1 Y 1 R ALA 668  ? C ALA 665  
701  1 Y 1 R GLY 669  ? C GLY 666  
702  1 Y 1 R ILE 670  ? C ILE 667  
703  1 Y 1 R CYS 671  ? C CYS 668  
704  1 Y 1 R ALA 672  ? C ALA 669  
705  1 Y 1 R SER 673  ? C SER 670  
706  1 Y 1 R TYR 674  ? C TYR 671  
707  1 Y 1 R GLN 675  ? C GLN 672  
708  1 Y 1 R THR 676  ? C THR 673  
709  1 Y 1 R GLN 677  ? C GLN 674  
710  1 Y 1 R THR 678  ? C THR 675  
711  1 Y 1 R ASN 679  ? C ASN 676  
712  1 Y 1 R SER 680  ? C SER 677  
713  1 Y 1 R PRO 681  ? C PRO 678  
714  1 Y 1 R GLY 682  ? C GLY 679  
715  1 Y 1 R SER 683  ? C SER 680  
716  1 Y 1 R ALA 684  ? C ALA 681  
717  1 Y 1 R SER 685  ? C SER 682  
718  1 Y 1 R SER 686  ? C SER 683  
719  1 Y 1 R VAL 687  ? C VAL 684  
720  1 Y 1 R ALA 688  ? C ALA 685  
721  1 Y 1 R SER 689  ? C SER 686  
722  1 Y 1 R GLN 690  ? C GLN 687  
723  1 Y 1 R SER 691  ? C SER 688  
724  1 Y 1 R ILE 692  ? C ILE 689  
725  1 Y 1 R ILE 693  ? C ILE 690  
726  1 Y 1 R ALA 694  ? C ALA 691  
727  1 Y 1 R TYR 695  ? C TYR 692  
728  1 Y 1 R THR 696  ? C THR 693  
729  1 Y 1 R MET 697  ? C MET 694  
730  1 Y 1 R SER 698  ? C SER 695  
731  1 Y 1 R LEU 699  ? C LEU 696  
732  1 Y 1 R GLY 700  ? C GLY 697  
733  1 Y 1 R VAL 701  ? C VAL 698  
734  1 Y 1 R GLU 702  ? C GLU 699  
735  1 Y 1 R ASN 703  ? C ASN 700  
736  1 Y 1 R SER 704  ? C SER 701  
737  1 Y 1 R VAL 705  ? C VAL 702  
738  1 Y 1 R ALA 706  ? C ALA 703  
739  1 Y 1 R TYR 707  ? C TYR 704  
740  1 Y 1 R SER 708  ? C SER 705  
741  1 Y 1 R ASN 709  ? C ASN 706  
742  1 Y 1 R ASN 710  ? C ASN 707  
743  1 Y 1 R SER 711  ? C SER 708  
744  1 Y 1 R ILE 712  ? C ILE 709  
745  1 Y 1 R ALA 713  ? C ALA 710  
746  1 Y 1 R ILE 714  ? C ILE 711  
747  1 Y 1 R PRO 715  ? C PRO 712  
748  1 Y 1 R THR 716  ? C THR 713  
749  1 Y 1 R ASN 717  ? C ASN 714  
750  1 Y 1 R PHE 718  ? C PHE 715  
751  1 Y 1 R THR 719  ? C THR 716  
752  1 Y 1 R ILE 720  ? C ILE 717  
753  1 Y 1 R SER 721  ? C SER 718  
754  1 Y 1 R VAL 722  ? C VAL 719  
755  1 Y 1 R THR 723  ? C THR 720  
756  1 Y 1 R THR 724  ? C THR 721  
757  1 Y 1 R GLU 725  ? C GLU 722  
758  1 Y 1 R ILE 726  ? C ILE 723  
759  1 Y 1 R LEU 727  ? C LEU 724  
760  1 Y 1 R PRO 728  ? C PRO 725  
761  1 Y 1 R VAL 729  ? C VAL 726  
762  1 Y 1 R SER 730  ? C SER 727  
763  1 Y 1 R MET 731  ? C MET 728  
764  1 Y 1 R THR 732  ? C THR 729  
765  1 Y 1 R LYS 733  ? C LYS 730  
766  1 Y 1 R THR 734  ? C THR 731  
767  1 Y 1 R SER 735  ? C SER 732  
768  1 Y 1 R VAL 736  ? C VAL 733  
769  1 Y 1 R ASP 737  ? C ASP 734  
770  1 Y 1 R CYS 738  ? C CYS 735  
771  1 Y 1 R THR 739  ? C THR 736  
772  1 Y 1 R MET 740  ? C MET 737  
773  1 Y 1 R TYR 741  ? C TYR 738  
774  1 Y 1 R ILE 742  ? C ILE 739  
775  1 Y 1 R CYS 743  ? C CYS 740  
776  1 Y 1 R GLY 744  ? C GLY 741  
777  1 Y 1 R ASP 745  ? C ASP 742  
778  1 Y 1 R SER 746  ? C SER 743  
779  1 Y 1 R THR 747  ? C THR 744  
780  1 Y 1 R GLU 748  ? C GLU 745  
781  1 Y 1 R CYS 749  ? C CYS 746  
782  1 Y 1 R SER 750  ? C SER 747  
783  1 Y 1 R ASN 751  ? C ASN 748  
784  1 Y 1 R LEU 752  ? C LEU 749  
785  1 Y 1 R LEU 753  ? C LEU 750  
786  1 Y 1 R LEU 754  ? C LEU 751  
787  1 Y 1 R GLN 755  ? C GLN 752  
788  1 Y 1 R TYR 756  ? C TYR 753  
789  1 Y 1 R GLY 757  ? C GLY 754  
790  1 Y 1 R SER 758  ? C SER 755  
791  1 Y 1 R PHE 759  ? C PHE 756  
792  1 Y 1 R CYS 760  ? C CYS 757  
793  1 Y 1 R THR 761  ? C THR 758  
794  1 Y 1 R GLN 762  ? C GLN 759  
795  1 Y 1 R LEU 763  ? C LEU 760  
796  1 Y 1 R ASN 764  ? C ASN 761  
797  1 Y 1 R ARG 765  ? C ARG 762  
798  1 Y 1 R ALA 766  ? C ALA 763  
799  1 Y 1 R LEU 767  ? C LEU 764  
800  1 Y 1 R THR 768  ? C THR 765  
801  1 Y 1 R GLY 769  ? C GLY 766  
802  1 Y 1 R ILE 770  ? C ILE 767  
803  1 Y 1 R ALA 771  ? C ALA 768  
804  1 Y 1 R VAL 772  ? C VAL 769  
805  1 Y 1 R GLU 773  ? C GLU 770  
806  1 Y 1 R GLN 774  ? C GLN 771  
807  1 Y 1 R ASP 775  ? C ASP 772  
808  1 Y 1 R LYS 776  ? C LYS 773  
809  1 Y 1 R ASN 777  ? C ASN 774  
810  1 Y 1 R THR 778  ? C THR 775  
811  1 Y 1 R GLN 779  ? C GLN 776  
812  1 Y 1 R GLU 780  ? C GLU 777  
813  1 Y 1 R VAL 781  ? C VAL 778  
814  1 Y 1 R PHE 782  ? C PHE 779  
815  1 Y 1 R ALA 783  ? C ALA 780  
816  1 Y 1 R GLN 784  ? C GLN 781  
817  1 Y 1 R VAL 785  ? C VAL 782  
818  1 Y 1 R LYS 786  ? C LYS 783  
819  1 Y 1 R GLN 787  ? C GLN 784  
820  1 Y 1 R ILE 788  ? C ILE 785  
821  1 Y 1 R TYR 789  ? C TYR 786  
822  1 Y 1 R LYS 790  ? C LYS 787  
823  1 Y 1 R THR 791  ? C THR 788  
824  1 Y 1 R PRO 792  ? C PRO 789  
825  1 Y 1 R PRO 793  ? C PRO 790  
826  1 Y 1 R ILE 794  ? C ILE 791  
827  1 Y 1 R LYS 795  ? C LYS 792  
828  1 Y 1 R ASP 796  ? C ASP 793  
829  1 Y 1 R PHE 797  ? C PHE 794  
830  1 Y 1 R GLY 798  ? C GLY 795  
831  1 Y 1 R GLY 799  ? C GLY 796  
832  1 Y 1 R PHE 800  ? C PHE 797  
833  1 Y 1 R ASN 801  ? C ASN 798  
834  1 Y 1 R PHE 802  ? C PHE 799  
835  1 Y 1 R SER 803  ? C SER 800  
836  1 Y 1 R GLN 804  ? C GLN 801  
837  1 Y 1 R ILE 805  ? C ILE 802  
838  1 Y 1 R LEU 806  ? C LEU 803  
839  1 Y 1 R PRO 807  ? C PRO 804  
840  1 Y 1 R ASP 808  ? C ASP 805  
841  1 Y 1 R PRO 809  ? C PRO 806  
842  1 Y 1 R SER 810  ? C SER 807  
843  1 Y 1 R LYS 811  ? C LYS 808  
844  1 Y 1 R PRO 812  ? C PRO 809  
845  1 Y 1 R SER 813  ? C SER 810  
846  1 Y 1 R LYS 814  ? C LYS 811  
847  1 Y 1 R ARG 815  ? C ARG 812  
848  1 Y 1 R SER 816  ? C SER 813  
849  1 Y 1 R PRO 817  ? C PRO 814  
850  1 Y 1 R ILE 818  ? C ILE 815  
851  1 Y 1 R GLU 819  ? C GLU 816  
852  1 Y 1 R ASP 820  ? C ASP 817  
853  1 Y 1 R LEU 821  ? C LEU 818  
854  1 Y 1 R LEU 822  ? C LEU 819  
855  1 Y 1 R PHE 823  ? C PHE 820  
856  1 Y 1 R ASN 824  ? C ASN 821  
857  1 Y 1 R LYS 825  ? C LYS 822  
858  1 Y 1 R VAL 826  ? C VAL 823  
859  1 Y 1 R THR 827  ? C THR 824  
860  1 Y 1 R LEU 828  ? C LEU 825  
861  1 Y 1 R ALA 829  ? C ALA 826  
862  1 Y 1 R ASP 830  ? C ASP 827  
863  1 Y 1 R ALA 831  ? C ALA 828  
864  1 Y 1 R GLY 832  ? C GLY 829  
865  1 Y 1 R PHE 833  ? C PHE 830  
866  1 Y 1 R ILE 834  ? C ILE 831  
867  1 Y 1 R LYS 835  ? C LYS 832  
868  1 Y 1 R GLN 836  ? C GLN 833  
869  1 Y 1 R TYR 837  ? C TYR 834  
870  1 Y 1 R GLY 838  ? C GLY 835  
871  1 Y 1 R ASP 839  ? C ASP 836  
872  1 Y 1 R CYS 840  ? C CYS 837  
873  1 Y 1 R LEU 841  ? C LEU 838  
874  1 Y 1 R GLY 842  ? C GLY 839  
875  1 Y 1 R ASP 843  ? C ASP 840  
876  1 Y 1 R ILE 844  ? C ILE 841  
877  1 Y 1 R ALA 845  ? C ALA 842  
878  1 Y 1 R ALA 846  ? C ALA 843  
879  1 Y 1 R ARG 847  ? C ARG 844  
880  1 Y 1 R ASP 848  ? C ASP 845  
881  1 Y 1 R LEU 849  ? C LEU 846  
882  1 Y 1 R ILE 850  ? C ILE 847  
883  1 Y 1 R CYS 851  ? C CYS 848  
884  1 Y 1 R ALA 852  ? C ALA 849  
885  1 Y 1 R GLN 853  ? C GLN 850  
886  1 Y 1 R LYS 854  ? C LYS 851  
887  1 Y 1 R PHE 855  ? C PHE 852  
888  1 Y 1 R ASN 856  ? C ASN 853  
889  1 Y 1 R GLY 857  ? C GLY 854  
890  1 Y 1 R LEU 858  ? C LEU 855  
891  1 Y 1 R THR 859  ? C THR 856  
892  1 Y 1 R VAL 860  ? C VAL 857  
893  1 Y 1 R LEU 861  ? C LEU 858  
894  1 Y 1 R PRO 862  ? C PRO 859  
895  1 Y 1 R PRO 863  ? C PRO 860  
896  1 Y 1 R LEU 864  ? C LEU 861  
897  1 Y 1 R LEU 865  ? C LEU 862  
898  1 Y 1 R THR 866  ? C THR 863  
899  1 Y 1 R ASP 867  ? C ASP 864  
900  1 Y 1 R GLU 868  ? C GLU 865  
901  1 Y 1 R MET 869  ? C MET 866  
902  1 Y 1 R ILE 870  ? C ILE 867  
903  1 Y 1 R ALA 871  ? C ALA 868  
904  1 Y 1 R GLN 872  ? C GLN 869  
905  1 Y 1 R TYR 873  ? C TYR 870  
906  1 Y 1 R THR 874  ? C THR 871  
907  1 Y 1 R SER 875  ? C SER 872  
908  1 Y 1 R ALA 876  ? C ALA 873  
909  1 Y 1 R LEU 877  ? C LEU 874  
910  1 Y 1 R LEU 878  ? C LEU 875  
911  1 Y 1 R ALA 879  ? C ALA 876  
912  1 Y 1 R GLY 880  ? C GLY 877  
913  1 Y 1 R THR 881  ? C THR 878  
914  1 Y 1 R ILE 882  ? C ILE 879  
915  1 Y 1 R THR 883  ? C THR 880  
916  1 Y 1 R SER 884  ? C SER 881  
917  1 Y 1 R GLY 885  ? C GLY 882  
918  1 Y 1 R TRP 886  ? C TRP 883  
919  1 Y 1 R THR 887  ? C THR 884  
920  1 Y 1 R PHE 888  ? C PHE 885  
921  1 Y 1 R GLY 889  ? C GLY 886  
922  1 Y 1 R ALA 890  ? C ALA 887  
923  1 Y 1 R GLY 891  ? C GLY 888  
924  1 Y 1 R PRO 892  ? C PRO 889  
925  1 Y 1 R ALA 893  ? C ALA 890  
926  1 Y 1 R LEU 894  ? C LEU 891  
927  1 Y 1 R GLN 895  ? C GLN 892  
928  1 Y 1 R ILE 896  ? C ILE 893  
929  1 Y 1 R PRO 897  ? C PRO 894  
930  1 Y 1 R PHE 898  ? C PHE 895  
931  1 Y 1 R PRO 899  ? C PRO 896  
932  1 Y 1 R MET 900  ? C MET 897  
933  1 Y 1 R GLN 901  ? C GLN 898  
934  1 Y 1 R MET 902  ? C MET 899  
935  1 Y 1 R ALA 903  ? C ALA 900  
936  1 Y 1 R TYR 904  ? C TYR 901  
937  1 Y 1 R ARG 905  ? C ARG 902  
938  1 Y 1 R PHE 906  ? C PHE 903  
939  1 Y 1 R ASN 907  ? C ASN 904  
940  1 Y 1 R GLY 908  ? C GLY 905  
941  1 Y 1 R ILE 909  ? C ILE 906  
942  1 Y 1 R GLY 910  ? C GLY 907  
943  1 Y 1 R VAL 911  ? C VAL 908  
944  1 Y 1 R THR 912  ? C THR 909  
945  1 Y 1 R GLN 913  ? C GLN 910  
946  1 Y 1 R ASN 914  ? C ASN 911  
947  1 Y 1 R VAL 915  ? C VAL 912  
948  1 Y 1 R LEU 916  ? C LEU 913  
949  1 Y 1 R TYR 917  ? C TYR 914  
950  1 Y 1 R GLU 918  ? C GLU 915  
951  1 Y 1 R ASN 919  ? C ASN 916  
952  1 Y 1 R GLN 920  ? C GLN 917  
953  1 Y 1 R LYS 921  ? C LYS 918  
954  1 Y 1 R LEU 922  ? C LEU 919  
955  1 Y 1 R ILE 923  ? C ILE 920  
956  1 Y 1 R ALA 924  ? C ALA 921  
957  1 Y 1 R ASN 925  ? C ASN 922  
958  1 Y 1 R GLN 926  ? C GLN 923  
959  1 Y 1 R PHE 927  ? C PHE 924  
960  1 Y 1 R ASN 928  ? C ASN 925  
961  1 Y 1 R SER 929  ? C SER 926  
962  1 Y 1 R ALA 930  ? C ALA 927  
963  1 Y 1 R ILE 931  ? C ILE 928  
964  1 Y 1 R GLY 932  ? C GLY 929  
965  1 Y 1 R LYS 933  ? C LYS 930  
966  1 Y 1 R ILE 934  ? C ILE 931  
967  1 Y 1 R GLN 935  ? C GLN 932  
968  1 Y 1 R ASP 936  ? C ASP 933  
969  1 Y 1 R SER 937  ? C SER 934  
970  1 Y 1 R LEU 938  ? C LEU 935  
971  1 Y 1 R SER 939  ? C SER 936  
972  1 Y 1 R SER 940  ? C SER 937  
973  1 Y 1 R THR 941  ? C THR 938  
974  1 Y 1 R PRO 942  ? C PRO 939  
975  1 Y 1 R SER 943  ? C SER 940  
976  1 Y 1 R ALA 944  ? C ALA 941  
977  1 Y 1 R LEU 945  ? C LEU 942  
978  1 Y 1 R GLY 946  ? C GLY 943  
979  1 Y 1 R LYS 947  ? C LYS 944  
980  1 Y 1 R LEU 948  ? C LEU 945  
981  1 Y 1 R GLN 949  ? C GLN 946  
982  1 Y 1 R ASP 950  ? C ASP 947  
983  1 Y 1 R VAL 951  ? C VAL 948  
984  1 Y 1 R VAL 952  ? C VAL 949  
985  1 Y 1 R ASN 953  ? C ASN 950  
986  1 Y 1 R GLN 954  ? C GLN 951  
987  1 Y 1 R ASN 955  ? C ASN 952  
988  1 Y 1 R ALA 956  ? C ALA 953  
989  1 Y 1 R GLN 957  ? C GLN 954  
990  1 Y 1 R ALA 958  ? C ALA 955  
991  1 Y 1 R LEU 959  ? C LEU 956  
992  1 Y 1 R ASN 960  ? C ASN 957  
993  1 Y 1 R THR 961  ? C THR 958  
994  1 Y 1 R LEU 962  ? C LEU 959  
995  1 Y 1 R VAL 963  ? C VAL 960  
996  1 Y 1 R LYS 964  ? C LYS 961  
997  1 Y 1 R GLN 965  ? C GLN 962  
998  1 Y 1 R LEU 966  ? C LEU 963  
999  1 Y 1 R SER 967  ? C SER 964  
1000 1 Y 1 R SER 968  ? C SER 965  
1001 1 Y 1 R ASN 969  ? C ASN 966  
1002 1 Y 1 R PHE 970  ? C PHE 967  
1003 1 Y 1 R GLY 971  ? C GLY 968  
1004 1 Y 1 R ALA 972  ? C ALA 969  
1005 1 Y 1 R ILE 973  ? C ILE 970  
1006 1 Y 1 R SER 974  ? C SER 971  
1007 1 Y 1 R SER 975  ? C SER 972  
1008 1 Y 1 R VAL 976  ? C VAL 973  
1009 1 Y 1 R LEU 977  ? C LEU 974  
1010 1 Y 1 R ASN 978  ? C ASN 975  
1011 1 Y 1 R ASP 979  ? C ASP 976  
1012 1 Y 1 R ILE 980  ? C ILE 977  
1013 1 Y 1 R LEU 981  ? C LEU 978  
1014 1 Y 1 R SER 982  ? C SER 979  
1015 1 Y 1 R ARG 983  ? C ARG 980  
1016 1 Y 1 R LEU 984  ? C LEU 981  
1017 1 Y 1 R ASP 985  ? C ASP 982  
1018 1 Y 1 R PRO 986  ? C PRO 983  
1019 1 Y 1 R PRO 987  ? C PRO 984  
1020 1 Y 1 R GLU 988  ? C GLU 985  
1021 1 Y 1 R ALA 989  ? C ALA 986  
1022 1 Y 1 R GLU 990  ? C GLU 987  
1023 1 Y 1 R VAL 991  ? C VAL 988  
1024 1 Y 1 R GLN 992  ? C GLN 989  
1025 1 Y 1 R ILE 993  ? C ILE 990  
1026 1 Y 1 R ASP 994  ? C ASP 991  
1027 1 Y 1 R ARG 995  ? C ARG 992  
1028 1 Y 1 R LEU 996  ? C LEU 993  
1029 1 Y 1 R ILE 997  ? C ILE 994  
1030 1 Y 1 R THR 998  ? C THR 995  
1031 1 Y 1 R GLY 999  ? C GLY 996  
1032 1 Y 1 R ARG 1000 ? C ARG 997  
1033 1 Y 1 R LEU 1001 ? C LEU 998  
1034 1 Y 1 R GLN 1002 ? C GLN 999  
1035 1 Y 1 R SER 1003 ? C SER 1000 
1036 1 Y 1 R LEU 1004 ? C LEU 1001 
1037 1 Y 1 R GLN 1005 ? C GLN 1002 
1038 1 Y 1 R THR 1006 ? C THR 1003 
1039 1 Y 1 R TYR 1007 ? C TYR 1004 
1040 1 Y 1 R VAL 1008 ? C VAL 1005 
1041 1 Y 1 R THR 1009 ? C THR 1006 
1042 1 Y 1 R GLN 1010 ? C GLN 1007 
1043 1 Y 1 R GLN 1011 ? C GLN 1008 
1044 1 Y 1 R LEU 1012 ? C LEU 1009 
1045 1 Y 1 R ILE 1013 ? C ILE 1010 
1046 1 Y 1 R ARG 1014 ? C ARG 1011 
1047 1 Y 1 R ALA 1015 ? C ALA 1012 
1048 1 Y 1 R ALA 1016 ? C ALA 1013 
1049 1 Y 1 R GLU 1017 ? C GLU 1014 
1050 1 Y 1 R ILE 1018 ? C ILE 1015 
1051 1 Y 1 R ARG 1019 ? C ARG 1016 
1052 1 Y 1 R ALA 1020 ? C ALA 1017 
1053 1 Y 1 R SER 1021 ? C SER 1018 
1054 1 Y 1 R ALA 1022 ? C ALA 1019 
1055 1 Y 1 R ASN 1023 ? C ASN 1020 
1056 1 Y 1 R LEU 1024 ? C LEU 1021 
1057 1 Y 1 R ALA 1025 ? C ALA 1022 
1058 1 Y 1 R ALA 1026 ? C ALA 1023 
1059 1 Y 1 R THR 1027 ? C THR 1024 
1060 1 Y 1 R LYS 1028 ? C LYS 1025 
1061 1 Y 1 R MET 1029 ? C MET 1026 
1062 1 Y 1 R SER 1030 ? C SER 1027 
1063 1 Y 1 R GLU 1031 ? C GLU 1028 
1064 1 Y 1 R CYS 1032 ? C CYS 1029 
1065 1 Y 1 R VAL 1033 ? C VAL 1030 
1066 1 Y 1 R LEU 1034 ? C LEU 1031 
1067 1 Y 1 R GLY 1035 ? C GLY 1032 
1068 1 Y 1 R GLN 1036 ? C GLN 1033 
1069 1 Y 1 R SER 1037 ? C SER 1034 
1070 1 Y 1 R LYS 1038 ? C LYS 1035 
1071 1 Y 1 R ARG 1039 ? C ARG 1036 
1072 1 Y 1 R VAL 1040 ? C VAL 1037 
1073 1 Y 1 R ASP 1041 ? C ASP 1038 
1074 1 Y 1 R PHE 1042 ? C PHE 1039 
1075 1 Y 1 R CYS 1043 ? C CYS 1040 
1076 1 Y 1 R GLY 1044 ? C GLY 1041 
1077 1 Y 1 R LYS 1045 ? C LYS 1042 
1078 1 Y 1 R GLY 1046 ? C GLY 1043 
1079 1 Y 1 R TYR 1047 ? C TYR 1044 
1080 1 Y 1 R HIS 1048 ? C HIS 1045 
1081 1 Y 1 R LEU 1049 ? C LEU 1046 
1082 1 Y 1 R MET 1050 ? C MET 1047 
1083 1 Y 1 R SER 1051 ? C SER 1048 
1084 1 Y 1 R PHE 1052 ? C PHE 1049 
1085 1 Y 1 R PRO 1053 ? C PRO 1050 
1086 1 Y 1 R GLN 1054 ? C GLN 1051 
1087 1 Y 1 R SER 1055 ? C SER 1052 
1088 1 Y 1 R ALA 1056 ? C ALA 1053 
1089 1 Y 1 R PRO 1057 ? C PRO 1054 
1090 1 Y 1 R HIS 1058 ? C HIS 1055 
1091 1 Y 1 R GLY 1059 ? C GLY 1056 
1092 1 Y 1 R VAL 1060 ? C VAL 1057 
1093 1 Y 1 R VAL 1061 ? C VAL 1058 
1094 1 Y 1 R PHE 1062 ? C PHE 1059 
1095 1 Y 1 R LEU 1063 ? C LEU 1060 
1096 1 Y 1 R HIS 1064 ? C HIS 1061 
1097 1 Y 1 R VAL 1065 ? C VAL 1062 
1098 1 Y 1 R THR 1066 ? C THR 1063 
1099 1 Y 1 R TYR 1067 ? C TYR 1064 
1100 1 Y 1 R VAL 1068 ? C VAL 1065 
1101 1 Y 1 R PRO 1069 ? C PRO 1066 
1102 1 Y 1 R ALA 1070 ? C ALA 1067 
1103 1 Y 1 R GLN 1071 ? C GLN 1068 
1104 1 Y 1 R GLU 1072 ? C GLU 1069 
1105 1 Y 1 R LYS 1073 ? C LYS 1070 
1106 1 Y 1 R ASN 1074 ? C ASN 1071 
1107 1 Y 1 R PHE 1075 ? C PHE 1072 
1108 1 Y 1 R THR 1076 ? C THR 1073 
1109 1 Y 1 R THR 1077 ? C THR 1074 
1110 1 Y 1 R ALA 1078 ? C ALA 1075 
1111 1 Y 1 R PRO 1079 ? C PRO 1076 
1112 1 Y 1 R ALA 1080 ? C ALA 1077 
1113 1 Y 1 R ILE 1081 ? C ILE 1078 
1114 1 Y 1 R CYS 1082 ? C CYS 1079 
1115 1 Y 1 R HIS 1083 ? C HIS 1080 
1116 1 Y 1 R ASP 1084 ? C ASP 1081 
1117 1 Y 1 R GLY 1085 ? C GLY 1082 
1118 1 Y 1 R LYS 1086 ? C LYS 1083 
1119 1 Y 1 R ALA 1087 ? C ALA 1084 
1120 1 Y 1 R HIS 1088 ? C HIS 1085 
1121 1 Y 1 R PHE 1089 ? C PHE 1086 
1122 1 Y 1 R PRO 1090 ? C PRO 1087 
1123 1 Y 1 R ARG 1091 ? C ARG 1088 
1124 1 Y 1 R GLU 1092 ? C GLU 1089 
1125 1 Y 1 R GLY 1093 ? C GLY 1090 
1126 1 Y 1 R VAL 1094 ? C VAL 1091 
1127 1 Y 1 R PHE 1095 ? C PHE 1092 
1128 1 Y 1 R VAL 1096 ? C VAL 1093 
1129 1 Y 1 R SER 1097 ? C SER 1094 
1130 1 Y 1 R ASN 1098 ? C ASN 1095 
1131 1 Y 1 R GLY 1099 ? C GLY 1096 
1132 1 Y 1 R THR 1100 ? C THR 1097 
1133 1 Y 1 R HIS 1101 ? C HIS 1098 
1134 1 Y 1 R TRP 1102 ? C TRP 1099 
1135 1 Y 1 R PHE 1103 ? C PHE 1100 
1136 1 Y 1 R VAL 1104 ? C VAL 1101 
1137 1 Y 1 R THR 1105 ? C THR 1102 
1138 1 Y 1 R GLN 1106 ? C GLN 1103 
1139 1 Y 1 R ARG 1107 ? C ARG 1104 
1140 1 Y 1 R ASN 1108 ? C ASN 1105 
1141 1 Y 1 R PHE 1109 ? C PHE 1106 
1142 1 Y 1 R TYR 1110 ? C TYR 1107 
1143 1 Y 1 R GLU 1111 ? C GLU 1108 
1144 1 Y 1 R PRO 1112 ? C PRO 1109 
1145 1 Y 1 R GLN 1113 ? C GLN 1110 
1146 1 Y 1 R ILE 1114 ? C ILE 1111 
1147 1 Y 1 R ILE 1115 ? C ILE 1112 
1148 1 Y 1 R THR 1116 ? C THR 1113 
1149 1 Y 1 R THR 1117 ? C THR 1114 
1150 1 Y 1 R ASP 1118 ? C ASP 1115 
1151 1 Y 1 R ASN 1119 ? C ASN 1116 
1152 1 Y 1 R THR 1120 ? C THR 1117 
1153 1 Y 1 R PHE 1121 ? C PHE 1118 
1154 1 Y 1 R VAL 1122 ? C VAL 1119 
1155 1 Y 1 R SER 1123 ? C SER 1120 
1156 1 Y 1 R GLY 1124 ? C GLY 1121 
1157 1 Y 1 R ASN 1125 ? C ASN 1122 
1158 1 Y 1 R CYS 1126 ? C CYS 1123 
1159 1 Y 1 R ASP 1127 ? C ASP 1124 
1160 1 Y 1 R VAL 1128 ? C VAL 1125 
1161 1 Y 1 R VAL 1129 ? C VAL 1126 
1162 1 Y 1 R ILE 1130 ? C ILE 1127 
1163 1 Y 1 R GLY 1131 ? C GLY 1128 
1164 1 Y 1 R ILE 1132 ? C ILE 1129 
1165 1 Y 1 R VAL 1133 ? C VAL 1130 
1166 1 Y 1 R ASN 1134 ? C ASN 1131 
1167 1 Y 1 R ASN 1135 ? C ASN 1132 
1168 1 Y 1 R THR 1136 ? C THR 1133 
1169 1 Y 1 R VAL 1137 ? C VAL 1134 
1170 1 Y 1 R TYR 1138 ? C TYR 1135 
1171 1 Y 1 R ASP 1139 ? C ASP 1136 
1172 1 Y 1 R PRO 1140 ? C PRO 1137 
1173 1 Y 1 R LEU 1141 ? C LEU 1138 
1174 1 Y 1 R GLN 1142 ? C GLN 1139 
1175 1 Y 1 R PRO 1143 ? C PRO 1140 
1176 1 Y 1 R GLU 1144 ? C GLU 1141 
1177 1 Y 1 R LEU 1145 ? C LEU 1142 
1178 1 Y 1 R ASP 1146 ? C ASP 1143 
1179 1 Y 1 R SER 1147 ? C SER 1144 
1180 1 Y 1 R PHE 1148 ? C PHE 1145 
1181 1 Y 1 R LYS 1149 ? C LYS 1146 
1182 1 Y 1 R GLU 1150 ? C GLU 1147 
1183 1 Y 1 R GLU 1151 ? C GLU 1148 
1184 1 Y 1 R LEU 1152 ? C LEU 1149 
1185 1 Y 1 R ASP 1153 ? C ASP 1150 
1186 1 Y 1 R LYS 1154 ? C LYS 1151 
1187 1 Y 1 R TYR 1155 ? C TYR 1152 
1188 1 Y 1 R PHE 1156 ? C PHE 1153 
1189 1 Y 1 R LYS 1157 ? C LYS 1154 
1190 1 Y 1 R ASN 1158 ? C ASN 1155 
1191 1 Y 1 R HIS 1159 ? C HIS 1156 
1192 1 Y 1 R THR 1160 ? C THR 1157 
1193 1 Y 1 R SER 1161 ? C SER 1158 
1194 1 Y 1 R PRO 1162 ? C PRO 1159 
1195 1 Y 1 R ASP 1163 ? C ASP 1160 
1196 1 Y 1 R VAL 1164 ? C VAL 1161 
1197 1 Y 1 R ASP 1165 ? C ASP 1162 
1198 1 Y 1 R LEU 1166 ? C LEU 1163 
1199 1 Y 1 R GLY 1167 ? C GLY 1164 
1200 1 Y 1 R ASP 1168 ? C ASP 1165 
1201 1 Y 1 R ILE 1169 ? C ILE 1166 
1202 1 Y 1 R SER 1170 ? C SER 1167 
1203 1 Y 1 R GLY 1171 ? C GLY 1168 
1204 1 Y 1 R ILE 1172 ? C ILE 1169 
1205 1 Y 1 R ASN 1173 ? C ASN 1170 
1206 1 Y 1 R ALA 1174 ? C ALA 1171 
1207 1 Y 1 R SER 1175 ? C SER 1172 
1208 1 Y 1 R VAL 1176 ? C VAL 1173 
1209 1 Y 1 R VAL 1177 ? C VAL 1174 
1210 1 Y 1 R ASN 1178 ? C ASN 1175 
1211 1 Y 1 R ILE 1179 ? C ILE 1176 
1212 1 Y 1 R GLN 1180 ? C GLN 1177 
1213 1 Y 1 R LYS 1181 ? C LYS 1178 
1214 1 Y 1 R GLU 1182 ? C GLU 1179 
1215 1 Y 1 R ILE 1183 ? C ILE 1180 
1216 1 Y 1 R ASP 1184 ? C ASP 1181 
1217 1 Y 1 R ARG 1185 ? C ARG 1182 
1218 1 Y 1 R LEU 1186 ? C LEU 1183 
1219 1 Y 1 R ASN 1187 ? C ASN 1184 
1220 1 Y 1 R GLU 1188 ? C GLU 1185 
1221 1 Y 1 R VAL 1189 ? C VAL 1186 
1222 1 Y 1 R ALA 1190 ? C ALA 1187 
1223 1 Y 1 R LYS 1191 ? C LYS 1188 
1224 1 Y 1 R ASN 1192 ? C ASN 1189 
1225 1 Y 1 R LEU 1193 ? C LEU 1190 
1226 1 Y 1 R ASN 1194 ? C ASN 1191 
1227 1 Y 1 R GLU 1195 ? C GLU 1192 
1228 1 Y 1 R SER 1196 ? C SER 1193 
1229 1 Y 1 R LEU 1197 ? C LEU 1194 
1230 1 Y 1 R ILE 1198 ? C ILE 1195 
1231 1 Y 1 R ASP 1199 ? C ASP 1196 
1232 1 Y 1 R LEU 1200 ? C LEU 1197 
1233 1 Y 1 R GLN 1201 ? C GLN 1198 
1234 1 Y 1 R GLU 1202 ? C GLU 1199 
1235 1 Y 1 R LEU 1203 ? C LEU 1200 
1236 1 Y 1 R GLY 1204 ? C GLY 1201 
1237 1 Y 1 R LYS 1205 ? C LYS 1202 
1238 1 Y 1 R TYR 1206 ? C TYR 1203 
1239 1 Y 1 R GLU 1207 ? C GLU 1204 
1240 1 Y 1 R GLN 1208 ? C GLN 1205 
1241 1 Y 1 R GLY 1209 ? C GLY 1206 
1242 1 Y 1 R SER 1210 ? C SER 1207 
1243 1 Y 1 R GLY 1211 ? C GLY 1208 
1244 1 Y 1 R TYR 1212 ? C TYR 1209 
1245 1 Y 1 R ILE 1213 ? C ILE 1210 
1246 1 Y 1 R PRO 1214 ? C PRO 1211 
1247 1 Y 1 R GLU 1215 ? C GLU 1212 
1248 1 Y 1 R ALA 1216 ? C ALA 1213 
1249 1 Y 1 R PRO 1217 ? C PRO 1214 
1250 1 Y 1 R ARG 1218 ? C ARG 1215 
1251 1 Y 1 R ASP 1219 ? C ASP 1216 
1252 1 Y 1 R GLY 1220 ? C GLY 1217 
1253 1 Y 1 R GLN 1221 ? C GLN 1218 
1254 1 Y 1 R ALA 1222 ? C ALA 1219 
1255 1 Y 1 R TYR 1223 ? C TYR 1220 
1256 1 Y 1 R VAL 1224 ? C VAL 1221 
1257 1 Y 1 R ARG 1225 ? C ARG 1222 
1258 1 Y 1 R LYS 1226 ? C LYS 1223 
1259 1 Y 1 R ASP 1227 ? C ASP 1224 
1260 1 Y 1 R GLY 1228 ? C GLY 1225 
1261 1 Y 1 R GLU 1229 ? C GLU 1226 
1262 1 Y 1 R TRP 1230 ? C TRP 1227 
1263 1 Y 1 R VAL 1231 ? C VAL 1228 
1264 1 Y 1 R LEU 1232 ? C LEU 1229 
1265 1 Y 1 R LEU 1233 ? C LEU 1230 
1266 1 Y 1 R SER 1234 ? C SER 1231 
1267 1 Y 1 R THR 1235 ? C THR 1232 
1268 1 Y 1 R PHE 1236 ? C PHE 1233 
1269 1 Y 1 R LEU 1237 ? C LEU 1234 
1270 1 Y 1 R GLY 1238 ? C GLY 1235 
1271 1 Y 1 R ARG 1239 ? C ARG 1236 
1272 1 Y 1 R SER 1240 ? C SER 1237 
1273 1 Y 1 R LEU 1241 ? C LEU 1238 
1274 1 Y 1 R GLU 1242 ? C GLU 1239 
1275 1 Y 1 R VAL 1243 ? C VAL 1240 
1276 1 Y 1 R LEU 1244 ? C LEU 1241 
1277 1 Y 1 R PHE 1245 ? C PHE 1242 
1278 1 Y 1 R GLN 1246 ? C GLN 1243 
1279 1 Y 1 R GLY 1247 ? C GLY 1244 
1280 1 Y 1 R PRO 1248 ? C PRO 1245 
1281 1 Y 1 R GLY 1249 ? C GLY 1246 
1282 1 Y 1 R HIS 1250 ? C HIS 1247 
1283 1 Y 1 R HIS 1251 ? C HIS 1248 
1284 1 Y 1 R HIS 1252 ? C HIS 1249 
1285 1 Y 1 R HIS 1253 ? C HIS 1250 
1286 1 Y 1 R HIS 1254 ? C HIS 1251 
1287 1 Y 1 R HIS 1255 ? C HIS 1252 
1288 1 Y 1 R HIS 1256 ? C HIS 1253 
1289 1 Y 1 R HIS 1257 ? C HIS 1254 
1290 1 Y 1 R SER 1258 ? C SER 1255 
1291 1 Y 1 R ALA 1259 ? C ALA 1256 
1292 1 Y 1 R TRP 1260 ? C TRP 1257 
1293 1 Y 1 R SER 1261 ? C SER 1258 
1294 1 Y 1 R HIS 1262 ? C HIS 1259 
1295 1 Y 1 R PRO 1263 ? C PRO 1260 
1296 1 Y 1 R GLN 1264 ? C GLN 1261 
1297 1 Y 1 R PHE 1265 ? C PHE 1262 
1298 1 Y 1 R GLU 1266 ? C GLU 1263 
1299 1 Y 1 R LYS 1267 ? C LYS 1264 
1300 1 Y 1 R GLY 1268 ? C GLY 1265 
1301 1 Y 1 R GLY 1269 ? C GLY 1266 
1302 1 Y 1 R GLY 1270 ? C GLY 1267 
1303 1 Y 1 R SER 1271 ? C SER 1268 
1304 1 Y 1 R GLY 1272 ? C GLY 1269 
1305 1 Y 1 R GLY 1273 ? C GLY 1270 
1306 1 Y 1 R GLY 1274 ? C GLY 1271 
1307 1 Y 1 R GLY 1275 ? C GLY 1272 
1308 1 Y 1 R SER 1276 ? C SER 1273 
1309 1 Y 1 R GLY 1277 ? C GLY 1274 
1310 1 Y 1 R GLY 1278 ? C GLY 1275 
1311 1 Y 1 R SER 1279 ? C SER 1276 
1312 1 Y 1 R ALA 1280 ? C ALA 1277 
1313 1 Y 1 R TRP 1281 ? C TRP 1278 
1314 1 Y 1 R SER 1282 ? C SER 1279 
1315 1 Y 1 R HIS 1283 ? C HIS 1280 
1316 1 Y 1 R PRO 1284 ? C PRO 1281 
1317 1 Y 1 R GLN 1285 ? C GLN 1282 
1318 1 Y 1 R PHE 1286 ? C PHE 1283 
1319 1 Y 1 R GLU 1287 ? C GLU 1284 
1320 1 Y 1 R LYS 1288 ? C LYS 1285 
1321 1 Y 1 N MET 1    ? D MET 1    
1322 1 Y 1 N PHE 2    ? D PHE 2    
1323 1 Y 1 N VAL 3    ? D VAL 3    
1324 1 Y 1 N PHE 4    ? D PHE 4    
1325 1 Y 1 N LEU 5    ? D LEU 5    
1326 1 Y 1 N VAL 6    ? D VAL 6    
1327 1 Y 1 N LEU 7    ? D LEU 7    
1328 1 Y 1 N LEU 8    ? D LEU 8    
1329 1 Y 1 N PRO 9    ? D PRO 9    
1330 1 Y 1 N LEU 10   ? D LEU 10   
1331 1 Y 1 N VAL 11   ? D VAL 11   
1332 1 Y 1 N SER 12   ? D SER 12   
1333 1 Y 1 N SER 13   ? D SER 13   
1334 1 Y 1 N GLN 14   ? D GLN 14   
1335 1 Y 1 N CYS 15   ? D CYS 15   
1336 1 Y 1 N VAL 16   ? D VAL 16   
1337 1 Y 1 N ASN 17   ? D ASN 17   
1338 1 Y 1 N PHE 18   ? D PHE 18   
1339 1 Y 1 N THR 19   ? D THR 19   
1340 1 Y 1 N THR 20   ? D THR 20   
1341 1 Y 1 N ARG 21   ? D ARG 21   
1342 1 Y 1 N THR 22   ? D THR 22   
1343 1 Y 1 N GLN 23   ? D GLN 23   
1344 1 Y 1 N LEU 24   ? D LEU 24   
1345 1 Y 1 N PRO 25   ? D PRO 25   
1346 1 Y 1 N PRO 26   ? D PRO 26   
1347 1 Y 1 N ALA 27   ? D ALA 27   
1348 1 Y 1 N SER 46   ? D SER 46   
1349 1 Y 1 N VAL 47   ? D VAL 47   
1350 1 Y 1 N LEU 48   ? D LEU 48   
1351 1 Y 1 N ALA 67   ? D ALA 67   
1352 1 Y 1 N ILE 68   ? D ILE 68   
1353 1 Y 1 N HIS 69   ? D HIS 69   
1354 1 Y 1 N VAL 70   ? D VAL 70   
1355 1 Y 1 N SER 71   ? D SER 71   
1356 1 Y 1 N GLY 72   ? D GLY 72   
1357 1 Y 1 N THR 73   ? D THR 73   
1358 1 Y 1 N ASN 74   ? D ASN 74   
1359 1 Y 1 N GLY 75   ? D GLY 75   
1360 1 Y 1 N THR 76   ? D THR 76   
1361 1 Y 1 N LYS 77   ? D LYS 77   
1362 1 Y 1 N ARG 78   ? D ARG 78   
1363 1 Y 1 N PHE 79   ? D PHE 79   
1364 1 Y 1 N ALA 80   ? D ALA 80   
1365 1 Y 1 N GLU 96   ? D GLU 96   
1366 1 Y 1 N LYS 97   ? D LYS 97   
1367 1 Y 1 N SER 98   ? D SER 98   
1368 1 Y 1 N ASN 99   ? D ASN 99   
1369 1 Y 1 N ILE 100  ? D ILE 100  
1370 1 Y 1 N ILE 101  ? D ILE 101  
1371 1 Y 1 N PHE 135  ? D PHE 135  
1372 1 Y 1 N CYS 136  ? D CYS 136  
1373 1 Y 1 N ASN 137  ? D ASN 137  
1374 1 Y 1 N ASP 138  ? D ASP 138  
1375 1 Y 1 N PRO 139  ? D PRO 139  
1376 1 Y 1 N PHE 140  ? D PHE 140  
1377 1 Y 1 N LEU 141  ? D LEU 141  
1378 1 Y 1 N GLY 142  ? D GLY 142  
1379 1 Y 1 N VAL 143  ? D VAL 143  
1380 1 Y 1 N TYR 144  ? D TYR 144  
1381 1 Y 1 N TYR 145  ? D TYR 145  
1382 1 Y 1 N HIS 146  ? D HIS 146  
1383 1 Y 1 N LYS 147  ? D LYS 147  
1384 1 Y 1 N ASN 148  ? D ASN 148  
1385 1 Y 1 N ASN 149  ? D ASN 149  
1386 1 Y 1 N LYS 150  ? D LYS 150  
1387 1 Y 1 N SER 151  ? D SER 151  
1388 1 Y 1 N TRP 152  ? D TRP 152  
1389 1 Y 1 N MET 153  ? D MET 153  
1390 1 Y 1 N GLU 154  ? D GLU 154  
1391 1 Y 1 N SER 155  ? D SER 155  
1392 1 Y 1 N GLU 156  ? D GLU 156  
1393 1 Y 1 N PHE 157  ? D PHE 157  
1394 1 Y 1 N ARG 158  ? D ARG 158  
1395 1 Y 1 N VAL 159  ? D VAL 159  
1396 1 Y 1 N LEU 176  ? D LEU 176  
1397 1 Y 1 N MET 177  ? D MET 177  
1398 1 Y 1 N ASP 178  ? D ASP 178  
1399 1 Y 1 N LEU 179  ? D LEU 179  
1400 1 Y 1 N GLU 180  ? D GLU 180  
1401 1 Y 1 N GLY 181  ? D GLY 181  
1402 1 Y 1 N LYS 182  ? D LYS 182  
1403 1 Y 1 N GLN 183  ? D GLN 183  
1404 1 Y 1 N GLY 184  ? D GLY 184  
1405 1 Y 1 N ASN 185  ? D ASN 185  
1406 1 Y 1 N PHE 186  ? D PHE 186  
1407 1 Y 1 N LYS 187  ? D LYS 187  
1408 1 Y 1 N ASN 188  ? D ASN 188  
1409 1 Y 1 N HIS 207  ? D HIS 207  
1410 1 Y 1 N THR 208  ? D THR 208  
1411 1 Y 1 N PRO 209  ? D PRO 209  
1412 1 Y 1 N ILE 210  ? D ILE 210  
1413 1 Y 1 N ASN 211  ? D ASN 211  
1414 1 Y 1 N LEU 212  ? D LEU 212  
1415 1 Y 1 N VAL 213  ? D VAL 213  
1416 1 Y 1 N ARG 214  ? D ARG 214  
1417 1 Y 1 N GLY 215  ? D GLY 215  
1418 1 Y 1 N LEU 216  ? D LEU 216  
1419 1 Y 1 N PRO 217  ? D PRO 217  
1420 1 Y 1 N GLN 218  ? D GLN 218  
1421 1 Y 1 N GLY 219  ? D GLY 219  
1422 1 Y 1 N PHE 220  ? D PHE 220  
1423 1 Y 1 N HIS 245  ? D HIS 242  
1424 1 Y 1 N ARG 246  ? D ARG 243  
1425 1 Y 1 N SER 247  ? D SER 244  
1426 1 Y 1 N TYR 248  ? D TYR 245  
1427 1 Y 1 N LEU 249  ? D LEU 246  
1428 1 Y 1 N THR 250  ? D THR 247  
1429 1 Y 1 N PRO 251  ? D PRO 248  
1430 1 Y 1 N GLY 252  ? D GLY 249  
1431 1 Y 1 N ASP 253  ? D ASP 250  
1432 1 Y 1 N SER 254  ? D SER 251  
1433 1 Y 1 N SER 255  ? D SER 252  
1434 1 Y 1 N SER 256  ? D SER 253  
1435 1 Y 1 N GLY 257  ? D GLY 254  
1436 1 Y 1 N TRP 258  ? D TRP 255  
1437 1 Y 1 N THR 259  ? D THR 256  
1438 1 Y 1 N ALA 260  ? D ALA 257  
1439 1 Y 1 N GLY 261  ? D GLY 258  
1440 1 Y 1 N ALA 262  ? D ALA 259  
1441 1 Y 1 N ALA 263  ? D ALA 260  
1442 1 Y 1 N ALA 264  ? D ALA 261  
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.ncbi_tax_id          3885 
_em_entity_assembly_recombinant.organism             'Phaseolus vulgaris' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                            1 
_em_image_recording.imaging_id                    1 
_em_image_recording.avg_electron_dose_per_image   54 
_em_image_recording.average_exposure_time         ? 
_em_image_recording.details                       ? 
_em_image_recording.detector_mode                 ? 
_em_image_recording.film_or_detector_model        'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.num_diffraction_images        ? 
_em_image_recording.num_grids_imaged              ? 
_em_image_recording.num_real_images               ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'CRYSTALLOGRAPHY MERGING'  ? ? ? 1 1 1 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
E 5 NAG 1 A NAG 1 N NAG 291 n 
E 5 NAG 2 A NAG 2 N NAG 292 n 
E 5 BMA 3 A BMA 3 N BMA 293 n 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
_pdbx_entity_branch.entity_id   5 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 5 DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-                                             'Glycam Condensed Sequence' GMML       1.0   
2 5 'WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1' WURCS                       PDB2Glycan 1.1.0 
3 5 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}'           LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 5 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 5 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
5 NAG 1 n 
5 NAG 2 n 
5 BMA 3 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 BMA ? ? BMA ? ? 'SUBJECT OF INVESTIGATION' ? 
2 NAG ? ? NAG ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
