data_7M3L
# 
_entry.id   7M3L 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.347 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7M3L         ? ? 
WWPDB D_1000255548 ? ? 
EMDB  EMD-23656    ? ? 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Canine parvovirus and Fab14 at partial occupancy' 
_pdbx_database_related.db_id          EMD-23656 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7M3L 
_pdbx_database_status.recvd_initial_deposition_date   2021-03-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Goteschius, D.J.' 1 0000-0002-6052-7141 
'Hartmann, S.R.'   2 0000-0001-9567-2587 
'Hafenstein, S.L.' 3 0000-0003-2609-4036 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            118 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'High-resolution asymmetric structure of a Fab-virus complex reveals overlap with the receptor binding site.' 
_citation.year                      2021 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2025452118 
_citation.pdbx_database_id_PubMed   34074770 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Goetschius, D.J.' 1  ?                   
primary 'Hartmann, S.R.'   2  0000-0001-9567-2587 
primary 'Organtini, L.J.'  3  0000-0002-2156-1523 
primary 'Callaway, H.'     4  ?                   
primary 'Huang, K.'        5  ?                   
primary 'Bator, C.M.'      6  ?                   
primary 'Ashley, R.E.'     7  ?                   
primary 'Makhov, A.M.'     8  0000-0002-7910-5766 
primary 'Conway, J.F.'     9  0000-0002-6581-4748 
primary 'Parrish, C.R.'    10 0000-0002-1836-6655 
primary 'Hafenstein, S.L.' 11 0000-0003-2609-4036 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer nat 'Capsid protein 2'  64705.559 1 ? ? ? ? 
2 polymer nat 'Fab14 Light Chain' 11981.362 1 ? ? ? ? 
3 polymer nat 'Fab14 Heavy Chain' 13104.530 1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        VP2 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MSDGAVQPDGGQPAVRNERATGSGNGSGGGGGGGSGGVGISTGTFNNQTEFKFLENGWVEITANSSRLVHLNMPESENYR
RVVVNNMDKTAVNGNMALDDIHAQIVTPWSLVDANAWGVWFNPGDWQLIVNTMSELHLVSFEQEIFNVVLKTVSESATQP
PTKVYNNDLTASLMVALDSNNTMPFTPAAMRSETLGFYPWKPTIPTPWRYYFQWDRTLIPSHTGTSGTPTNIYHGTDPDD
VQFYTIENSVPVHLLRTGDEFATGTFFFDCKPCRLTHTWQTNRALGLPPFLNSLPQSEGATNFGDIGVQQDKRRGVTQMG
NTNYITEATIMRPAEVGYSAPYYSFEASTQGPFKTPIAAGRGGAQTDENQAADGNPRYAFGRQHGQKTTTTGETPERFTY
IAHQDTGRYPEGDWIQNINFNLPVTNDNVLLPTDPIGGKTGINYTNIFNTYGPLTALNNVPPVYPNGQIWDKEFDTDLKP
RLHVNAPFVCQNNCPGQLFVKVAPNLTNEYDPDASANMSRIVTYSDFWWKGKLVFKAKLRASHTWNPIQQMSINVDNQFN
YVPSNIGGMKIVYEKSQLAPRKLY
;
;MSDGAVQPDGGQPAVRNERATGSGNGSGGGGGGGSGGVGISTGTFNNQTEFKFLENGWVEITANSSRLVHLNMPESENYR
RVVVNNMDKTAVNGNMALDDIHAQIVTPWSLVDANAWGVWFNPGDWQLIVNTMSELHLVSFEQEIFNVVLKTVSESATQP
PTKVYNNDLTASLMVALDSNNTMPFTPAAMRSETLGFYPWKPTIPTPWRYYFQWDRTLIPSHTGTSGTPTNIYHGTDPDD
VQFYTIENSVPVHLLRTGDEFATGTFFFDCKPCRLTHTWQTNRALGLPPFLNSLPQSEGATNFGDIGVQQDKRRGVTQMG
NTNYITEATIMRPAEVGYSAPYYSFEASTQGPFKTPIAAGRGGAQTDENQAADGNPRYAFGRQHGQKTTTTGETPERFTY
IAHQDTGRYPEGDWIQNINFNLPVTNDNVLLPTDPIGGKTGINYTNIFNTYGPLTALNNVPPVYPNGQIWDKEFDTDLKP
RLHVNAPFVCQNNCPGQLFVKVAPNLTNEYDPDASANMSRIVTYSDFWWKGKLVFKAKLRASHTWNPIQQMSINVDNQFN
YVPSNIGGMKIVYEKSQLAPRKLY
;
A1 ? 
2 'polypeptide(L)' no no 
;DIVMTQSHKFMSTSVGDRVSITCKASQDVNTALAWYQQIPGQSPKLLIYSASNRYTGVPDRFTASGSGTDFTFTISSVQA
EDLALYYCQQHYTTPWTFGGGTKLEIKR
;
;DIVMTQSHKFMSTSVGDRVSITCKASQDVNTALAWYQQIPGQSPKLLIYSASNRYTGVPDRFTASGSGTDFTFTISSVQA
EDLALYYCQQHYTTPWTFGGGTKLEIKR
;
L2 ? 
3 'polypeptide(L)' no no 
;AVHLQGTELVKPGASAGVKLSCKASGYTFTNYDMNWVRQRPEQGLEWIGWIFPGDGSTRYNEKFKGKATLTTDKSSSTAY
QLNRLTSEDSAVYFCARRGSHGSYSFAYWGQGTLVTVSG
;
;AVHLQGTELVKPGASAGVKLSCKASGYTFTNYDMNWVRQRPEQGLEWIGWIFPGDGSTRYNEKFKGKATLTTDKSSSTAY
QLNRLTSEDSAVYFCARRGSHGSYSFAYWGQGTLVTVSG
;
H2 ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   ASP n 
1 4   GLY n 
1 5   ALA n 
1 6   VAL n 
1 7   GLN n 
1 8   PRO n 
1 9   ASP n 
1 10  GLY n 
1 11  GLY n 
1 12  GLN n 
1 13  PRO n 
1 14  ALA n 
1 15  VAL n 
1 16  ARG n 
1 17  ASN n 
1 18  GLU n 
1 19  ARG n 
1 20  ALA n 
1 21  THR n 
1 22  GLY n 
1 23  SER n 
1 24  GLY n 
1 25  ASN n 
1 26  GLY n 
1 27  SER n 
1 28  GLY n 
1 29  GLY n 
1 30  GLY n 
1 31  GLY n 
1 32  GLY n 
1 33  GLY n 
1 34  GLY n 
1 35  SER n 
1 36  GLY n 
1 37  GLY n 
1 38  VAL n 
1 39  GLY n 
1 40  ILE n 
1 41  SER n 
1 42  THR n 
1 43  GLY n 
1 44  THR n 
1 45  PHE n 
1 46  ASN n 
1 47  ASN n 
1 48  GLN n 
1 49  THR n 
1 50  GLU n 
1 51  PHE n 
1 52  LYS n 
1 53  PHE n 
1 54  LEU n 
1 55  GLU n 
1 56  ASN n 
1 57  GLY n 
1 58  TRP n 
1 59  VAL n 
1 60  GLU n 
1 61  ILE n 
1 62  THR n 
1 63  ALA n 
1 64  ASN n 
1 65  SER n 
1 66  SER n 
1 67  ARG n 
1 68  LEU n 
1 69  VAL n 
1 70  HIS n 
1 71  LEU n 
1 72  ASN n 
1 73  MET n 
1 74  PRO n 
1 75  GLU n 
1 76  SER n 
1 77  GLU n 
1 78  ASN n 
1 79  TYR n 
1 80  ARG n 
1 81  ARG n 
1 82  VAL n 
1 83  VAL n 
1 84  VAL n 
1 85  ASN n 
1 86  ASN n 
1 87  MET n 
1 88  ASP n 
1 89  LYS n 
1 90  THR n 
1 91  ALA n 
1 92  VAL n 
1 93  ASN n 
1 94  GLY n 
1 95  ASN n 
1 96  MET n 
1 97  ALA n 
1 98  LEU n 
1 99  ASP n 
1 100 ASP n 
1 101 ILE n 
1 102 HIS n 
1 103 ALA n 
1 104 GLN n 
1 105 ILE n 
1 106 VAL n 
1 107 THR n 
1 108 PRO n 
1 109 TRP n 
1 110 SER n 
1 111 LEU n 
1 112 VAL n 
1 113 ASP n 
1 114 ALA n 
1 115 ASN n 
1 116 ALA n 
1 117 TRP n 
1 118 GLY n 
1 119 VAL n 
1 120 TRP n 
1 121 PHE n 
1 122 ASN n 
1 123 PRO n 
1 124 GLY n 
1 125 ASP n 
1 126 TRP n 
1 127 GLN n 
1 128 LEU n 
1 129 ILE n 
1 130 VAL n 
1 131 ASN n 
1 132 THR n 
1 133 MET n 
1 134 SER n 
1 135 GLU n 
1 136 LEU n 
1 137 HIS n 
1 138 LEU n 
1 139 VAL n 
1 140 SER n 
1 141 PHE n 
1 142 GLU n 
1 143 GLN n 
1 144 GLU n 
1 145 ILE n 
1 146 PHE n 
1 147 ASN n 
1 148 VAL n 
1 149 VAL n 
1 150 LEU n 
1 151 LYS n 
1 152 THR n 
1 153 VAL n 
1 154 SER n 
1 155 GLU n 
1 156 SER n 
1 157 ALA n 
1 158 THR n 
1 159 GLN n 
1 160 PRO n 
1 161 PRO n 
1 162 THR n 
1 163 LYS n 
1 164 VAL n 
1 165 TYR n 
1 166 ASN n 
1 167 ASN n 
1 168 ASP n 
1 169 LEU n 
1 170 THR n 
1 171 ALA n 
1 172 SER n 
1 173 LEU n 
1 174 MET n 
1 175 VAL n 
1 176 ALA n 
1 177 LEU n 
1 178 ASP n 
1 179 SER n 
1 180 ASN n 
1 181 ASN n 
1 182 THR n 
1 183 MET n 
1 184 PRO n 
1 185 PHE n 
1 186 THR n 
1 187 PRO n 
1 188 ALA n 
1 189 ALA n 
1 190 MET n 
1 191 ARG n 
1 192 SER n 
1 193 GLU n 
1 194 THR n 
1 195 LEU n 
1 196 GLY n 
1 197 PHE n 
1 198 TYR n 
1 199 PRO n 
1 200 TRP n 
1 201 LYS n 
1 202 PRO n 
1 203 THR n 
1 204 ILE n 
1 205 PRO n 
1 206 THR n 
1 207 PRO n 
1 208 TRP n 
1 209 ARG n 
1 210 TYR n 
1 211 TYR n 
1 212 PHE n 
1 213 GLN n 
1 214 TRP n 
1 215 ASP n 
1 216 ARG n 
1 217 THR n 
1 218 LEU n 
1 219 ILE n 
1 220 PRO n 
1 221 SER n 
1 222 HIS n 
1 223 THR n 
1 224 GLY n 
1 225 THR n 
1 226 SER n 
1 227 GLY n 
1 228 THR n 
1 229 PRO n 
1 230 THR n 
1 231 ASN n 
1 232 ILE n 
1 233 TYR n 
1 234 HIS n 
1 235 GLY n 
1 236 THR n 
1 237 ASP n 
1 238 PRO n 
1 239 ASP n 
1 240 ASP n 
1 241 VAL n 
1 242 GLN n 
1 243 PHE n 
1 244 TYR n 
1 245 THR n 
1 246 ILE n 
1 247 GLU n 
1 248 ASN n 
1 249 SER n 
1 250 VAL n 
1 251 PRO n 
1 252 VAL n 
1 253 HIS n 
1 254 LEU n 
1 255 LEU n 
1 256 ARG n 
1 257 THR n 
1 258 GLY n 
1 259 ASP n 
1 260 GLU n 
1 261 PHE n 
1 262 ALA n 
1 263 THR n 
1 264 GLY n 
1 265 THR n 
1 266 PHE n 
1 267 PHE n 
1 268 PHE n 
1 269 ASP n 
1 270 CYS n 
1 271 LYS n 
1 272 PRO n 
1 273 CYS n 
1 274 ARG n 
1 275 LEU n 
1 276 THR n 
1 277 HIS n 
1 278 THR n 
1 279 TRP n 
1 280 GLN n 
1 281 THR n 
1 282 ASN n 
1 283 ARG n 
1 284 ALA n 
1 285 LEU n 
1 286 GLY n 
1 287 LEU n 
1 288 PRO n 
1 289 PRO n 
1 290 PHE n 
1 291 LEU n 
1 292 ASN n 
1 293 SER n 
1 294 LEU n 
1 295 PRO n 
1 296 GLN n 
1 297 SER n 
1 298 GLU n 
1 299 GLY n 
1 300 ALA n 
1 301 THR n 
1 302 ASN n 
1 303 PHE n 
1 304 GLY n 
1 305 ASP n 
1 306 ILE n 
1 307 GLY n 
1 308 VAL n 
1 309 GLN n 
1 310 GLN n 
1 311 ASP n 
1 312 LYS n 
1 313 ARG n 
1 314 ARG n 
1 315 GLY n 
1 316 VAL n 
1 317 THR n 
1 318 GLN n 
1 319 MET n 
1 320 GLY n 
1 321 ASN n 
1 322 THR n 
1 323 ASN n 
1 324 TYR n 
1 325 ILE n 
1 326 THR n 
1 327 GLU n 
1 328 ALA n 
1 329 THR n 
1 330 ILE n 
1 331 MET n 
1 332 ARG n 
1 333 PRO n 
1 334 ALA n 
1 335 GLU n 
1 336 VAL n 
1 337 GLY n 
1 338 TYR n 
1 339 SER n 
1 340 ALA n 
1 341 PRO n 
1 342 TYR n 
1 343 TYR n 
1 344 SER n 
1 345 PHE n 
1 346 GLU n 
1 347 ALA n 
1 348 SER n 
1 349 THR n 
1 350 GLN n 
1 351 GLY n 
1 352 PRO n 
1 353 PHE n 
1 354 LYS n 
1 355 THR n 
1 356 PRO n 
1 357 ILE n 
1 358 ALA n 
1 359 ALA n 
1 360 GLY n 
1 361 ARG n 
1 362 GLY n 
1 363 GLY n 
1 364 ALA n 
1 365 GLN n 
1 366 THR n 
1 367 ASP n 
1 368 GLU n 
1 369 ASN n 
1 370 GLN n 
1 371 ALA n 
1 372 ALA n 
1 373 ASP n 
1 374 GLY n 
1 375 ASN n 
1 376 PRO n 
1 377 ARG n 
1 378 TYR n 
1 379 ALA n 
1 380 PHE n 
1 381 GLY n 
1 382 ARG n 
1 383 GLN n 
1 384 HIS n 
1 385 GLY n 
1 386 GLN n 
1 387 LYS n 
1 388 THR n 
1 389 THR n 
1 390 THR n 
1 391 THR n 
1 392 GLY n 
1 393 GLU n 
1 394 THR n 
1 395 PRO n 
1 396 GLU n 
1 397 ARG n 
1 398 PHE n 
1 399 THR n 
1 400 TYR n 
1 401 ILE n 
1 402 ALA n 
1 403 HIS n 
1 404 GLN n 
1 405 ASP n 
1 406 THR n 
1 407 GLY n 
1 408 ARG n 
1 409 TYR n 
1 410 PRO n 
1 411 GLU n 
1 412 GLY n 
1 413 ASP n 
1 414 TRP n 
1 415 ILE n 
1 416 GLN n 
1 417 ASN n 
1 418 ILE n 
1 419 ASN n 
1 420 PHE n 
1 421 ASN n 
1 422 LEU n 
1 423 PRO n 
1 424 VAL n 
1 425 THR n 
1 426 ASN n 
1 427 ASP n 
1 428 ASN n 
1 429 VAL n 
1 430 LEU n 
1 431 LEU n 
1 432 PRO n 
1 433 THR n 
1 434 ASP n 
1 435 PRO n 
1 436 ILE n 
1 437 GLY n 
1 438 GLY n 
1 439 LYS n 
1 440 THR n 
1 441 GLY n 
1 442 ILE n 
1 443 ASN n 
1 444 TYR n 
1 445 THR n 
1 446 ASN n 
1 447 ILE n 
1 448 PHE n 
1 449 ASN n 
1 450 THR n 
1 451 TYR n 
1 452 GLY n 
1 453 PRO n 
1 454 LEU n 
1 455 THR n 
1 456 ALA n 
1 457 LEU n 
1 458 ASN n 
1 459 ASN n 
1 460 VAL n 
1 461 PRO n 
1 462 PRO n 
1 463 VAL n 
1 464 TYR n 
1 465 PRO n 
1 466 ASN n 
1 467 GLY n 
1 468 GLN n 
1 469 ILE n 
1 470 TRP n 
1 471 ASP n 
1 472 LYS n 
1 473 GLU n 
1 474 PHE n 
1 475 ASP n 
1 476 THR n 
1 477 ASP n 
1 478 LEU n 
1 479 LYS n 
1 480 PRO n 
1 481 ARG n 
1 482 LEU n 
1 483 HIS n 
1 484 VAL n 
1 485 ASN n 
1 486 ALA n 
1 487 PRO n 
1 488 PHE n 
1 489 VAL n 
1 490 CYS n 
1 491 GLN n 
1 492 ASN n 
1 493 ASN n 
1 494 CYS n 
1 495 PRO n 
1 496 GLY n 
1 497 GLN n 
1 498 LEU n 
1 499 PHE n 
1 500 VAL n 
1 501 LYS n 
1 502 VAL n 
1 503 ALA n 
1 504 PRO n 
1 505 ASN n 
1 506 LEU n 
1 507 THR n 
1 508 ASN n 
1 509 GLU n 
1 510 TYR n 
1 511 ASP n 
1 512 PRO n 
1 513 ASP n 
1 514 ALA n 
1 515 SER n 
1 516 ALA n 
1 517 ASN n 
1 518 MET n 
1 519 SER n 
1 520 ARG n 
1 521 ILE n 
1 522 VAL n 
1 523 THR n 
1 524 TYR n 
1 525 SER n 
1 526 ASP n 
1 527 PHE n 
1 528 TRP n 
1 529 TRP n 
1 530 LYS n 
1 531 GLY n 
1 532 LYS n 
1 533 LEU n 
1 534 VAL n 
1 535 PHE n 
1 536 LYS n 
1 537 ALA n 
1 538 LYS n 
1 539 LEU n 
1 540 ARG n 
1 541 ALA n 
1 542 SER n 
1 543 HIS n 
1 544 THR n 
1 545 TRP n 
1 546 ASN n 
1 547 PRO n 
1 548 ILE n 
1 549 GLN n 
1 550 GLN n 
1 551 MET n 
1 552 SER n 
1 553 ILE n 
1 554 ASN n 
1 555 VAL n 
1 556 ASP n 
1 557 ASN n 
1 558 GLN n 
1 559 PHE n 
1 560 ASN n 
1 561 TYR n 
1 562 VAL n 
1 563 PRO n 
1 564 SER n 
1 565 ASN n 
1 566 ILE n 
1 567 GLY n 
1 568 GLY n 
1 569 MET n 
1 570 LYS n 
1 571 ILE n 
1 572 VAL n 
1 573 TYR n 
1 574 GLU n 
1 575 LYS n 
1 576 SER n 
1 577 GLN n 
1 578 LEU n 
1 579 ALA n 
1 580 PRO n 
1 581 ARG n 
1 582 LYS n 
1 583 LEU n 
1 584 TYR n 
2 1   ASP n 
2 2   ILE n 
2 3   VAL n 
2 4   MET n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   HIS n 
2 9   LYS n 
2 10  PHE n 
2 11  MET n 
2 12  SER n 
2 13  THR n 
2 14  SER n 
2 15  VAL n 
2 16  GLY n 
2 17  ASP n 
2 18  ARG n 
2 19  VAL n 
2 20  SER n 
2 21  ILE n 
2 22  THR n 
2 23  CYS n 
2 24  LYS n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  ASP n 
2 29  VAL n 
2 30  ASN n 
2 31  THR n 
2 32  ALA n 
2 33  LEU n 
2 34  ALA n 
2 35  TRP n 
2 36  TYR n 
2 37  GLN n 
2 38  GLN n 
2 39  ILE n 
2 40  PRO n 
2 41  GLY n 
2 42  GLN n 
2 43  SER n 
2 44  PRO n 
2 45  LYS n 
2 46  LEU n 
2 47  LEU n 
2 48  ILE n 
2 49  TYR n 
2 50  SER n 
2 51  ALA n 
2 52  SER n 
2 53  ASN n 
2 54  ARG n 
2 55  TYR n 
2 56  THR n 
2 57  GLY n 
2 58  VAL n 
2 59  PRO n 
2 60  ASP n 
2 61  ARG n 
2 62  PHE n 
2 63  THR n 
2 64  ALA n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  GLY n 
2 69  THR n 
2 70  ASP n 
2 71  PHE n 
2 72  THR n 
2 73  PHE n 
2 74  THR n 
2 75  ILE n 
2 76  SER n 
2 77  SER n 
2 78  VAL n 
2 79  GLN n 
2 80  ALA n 
2 81  GLU n 
2 82  ASP n 
2 83  LEU n 
2 84  ALA n 
2 85  LEU n 
2 86  TYR n 
2 87  TYR n 
2 88  CYS n 
2 89  GLN n 
2 90  GLN n 
2 91  HIS n 
2 92  TYR n 
2 93  THR n 
2 94  THR n 
2 95  PRO n 
2 96  TRP n 
2 97  THR n 
2 98  PHE n 
2 99  GLY n 
2 100 GLY n 
2 101 GLY n 
2 102 THR n 
2 103 LYS n 
2 104 LEU n 
2 105 GLU n 
2 106 ILE n 
2 107 LYS n 
2 108 ARG n 
3 1   ALA n 
3 2   VAL n 
3 3   HIS n 
3 4   LEU n 
3 5   GLN n 
3 6   GLY n 
3 7   THR n 
3 8   GLU n 
3 9   LEU n 
3 10  VAL n 
3 11  LYS n 
3 12  PRO n 
3 13  GLY n 
3 14  ALA n 
3 15  SER n 
3 16  ALA n 
3 17  GLY n 
3 18  VAL n 
3 19  LYS n 
3 20  LEU n 
3 21  SER n 
3 22  CYS n 
3 23  LYS n 
3 24  ALA n 
3 25  SER n 
3 26  GLY n 
3 27  TYR n 
3 28  THR n 
3 29  PHE n 
3 30  THR n 
3 31  ASN n 
3 32  TYR n 
3 33  ASP n 
3 34  MET n 
3 35  ASN n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ARG n 
3 41  PRO n 
3 42  GLU n 
3 43  GLN n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  ILE n 
3 49  GLY n 
3 50  TRP n 
3 51  ILE n 
3 52  PHE n 
3 53  PRO n 
3 54  GLY n 
3 55  ASP n 
3 56  GLY n 
3 57  SER n 
3 58  THR n 
3 59  ARG n 
3 60  TYR n 
3 61  ASN n 
3 62  GLU n 
3 63  LYS n 
3 64  PHE n 
3 65  LYS n 
3 66  GLY n 
3 67  LYS n 
3 68  ALA n 
3 69  THR n 
3 70  LEU n 
3 71  THR n 
3 72  THR n 
3 73  ASP n 
3 74  LYS n 
3 75  SER n 
3 76  SER n 
3 77  SER n 
3 78  THR n 
3 79  ALA n 
3 80  TYR n 
3 81  GLN n 
3 82  LEU n 
3 83  ASN n 
3 84  ARG n 
3 85  LEU n 
3 86  THR n 
3 87  SER n 
3 88  GLU n 
3 89  ASP n 
3 90  SER n 
3 91  ALA n 
3 92  VAL n 
3 93  TYR n 
3 94  PHE n 
3 95  CYS n 
3 96  ALA n 
3 97  ARG n 
3 98  ARG n 
3 99  GLY n 
3 100 SER n 
3 101 HIS n 
3 102 GLY n 
3 103 SER n 
3 104 TYR n 
3 105 SER n 
3 106 PHE n 
3 107 ALA n 
3 108 TYR n 
3 109 TRP n 
3 110 GLY n 
3 111 GLN n 
3 112 GLY n 
3 113 THR n 
3 114 LEU n 
3 115 VAL n 
3 116 THR n 
3 117 VAL n 
3 118 SER n 
3 119 GLY n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 584 CPV-2 'Canine parvovirus type 2' 10788 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 108 ?     'Mus musculus'             10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 1 119 ?     'Mus musculus'             10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP B2ZG07_PAVC B2ZG07 ? 1 
;MSDGAVQPDGGQPAVRNERATGSGNGSGGGGGGGSGGVGISTGTFNNQTEFKFLENGWVEITANSSRLVHLNMPESENYR
RVVVNNMDKTAVNGNMALDDIHAQIVTPWSLVDANAWGVWFNPGDWQLIVNTMSELHLVSFEQEIFNVVLKTVSESATQP
PTKVYNNDLTASLMVALDSNNTMPFTPAAMRSETLGFYPWKPTIPTPWRYYFQWDRTLIPSHTGTSGTPTNIYHGTDPDD
VQFYTIENSVPVHLLRTGDEFATGTFFFDCKPCRLTHTWQTNRALGLPPFLNSLPQSEGATNFGDIGVQQDKRRGVTQMG
NTNYITEATIMRPAEVGYSAPYYSFEASTQGPFKTPIAAGRGGAQTDENQAADGNPRYAFGRQHGQKTTTTGETPERFTY
IAHQDTGRYPEGDWIQNINFNLPVTNDNVLLPTDPIGGKTGINYTNIFNTYGPLTALNNVPPVYPNGQIWDKEFDTDLKP
RLHVNAPFVCQNNCPGQLFVKVAPNLTNEYDPDASANMSRIVTYSDFWWKGKLVFKAKLRASHTWNPIQQMSINVDNQFN
YVPSNIGGMKIVYEKSQLAPRKLY
;
1 
2 PDB 7M3L        7M3L   ? 2 ? 1 
3 PDB 7M3L        7M3L   ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7M3L A1 1 ? 584 ? B2ZG07 1 ? 584 ? 1 584 
2 2 7M3L L2 1 ? 108 ? 7M3L   1 ? 108 ? 1 108 
3 3 7M3L H2 1 ? 119 ? 7M3L   1 ? 119 ? 1 119 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7M3L 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7M3L 
_struct.title                        'Canine parvovirus and Fab14 at partial occupancy' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7M3L 
_struct_keywords.text            'canine parvovirus, CPV, Fab14, VIRUS, VIRUS-Immune System complex' 
_struct_keywords.pdbx_keywords   'VIRUS/Immune System' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 116 ? TRP A 120 ? ALA A1 116 TRP A1 120 5 ? 5 
HELX_P HELX_P2  AA2 ASN A 122 ? TRP A 126 ? ASN A1 122 TRP A1 126 5 ? 5 
HELX_P HELX_P3  AA3 GLN A 309 ? ARG A 313 ? GLN A1 309 ARG A1 313 5 ? 5 
HELX_P HELX_P4  AA4 TYR A 409 ? ASP A 413 ? TYR A1 409 ASP A1 413 5 ? 5 
HELX_P HELX_P5  AA5 THR A 425 ? ASP A 427 ? THR A1 425 ASP A1 427 5 ? 3 
HELX_P HELX_P6  AA6 ASN A 443 ? ILE A 447 ? ASN A1 443 ILE A1 447 5 ? 5 
HELX_P HELX_P7  AA7 ASN A 554 ? GLN A 558 ? ASN A1 554 GLN A1 558 5 ? 5 
HELX_P HELX_P8  AA8 GLN B 79  ? LEU B 83  ? GLN L2 79  LEU L2 83  5 ? 5 
HELX_P HELX_P9  AA9 THR C 28  ? TYR C 32  ? THR H2 28  TYR H2 32  5 ? 5 
HELX_P HELX_P10 AB1 GLU C 62  ? LYS C 65  ? GLU H2 62  LYS H2 65  5 ? 4 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 88 SG ? ? L2 CYS 23 L2 CYS 88 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf2 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 95 SG ? ? H2 CYS 22 H2 CYS 95 1_555 ? ? ? ? ? ? ? 2.020 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 464 A . ? TYR 464 A1 PRO 465 A ? PRO 465 A1 1 -7.51 
2 THR 94  B . ? THR 94  L2 PRO 95  B ? PRO 95  L2 1 3.84  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 5 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 2 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 4 ? 
AB6 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? parallel      
AA7 1 2 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? parallel      
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 49  ? PHE A 53  ? THR A1 49  PHE A1 53  
AA1 2 TRP A 58  ? ASN A 72  ? TRP A1 58  ASN A1 72  
AA1 3 THR A 523 ? LEU A 539 ? THR A1 523 LEU A1 539 
AA1 4 MET A 133 ? PHE A 146 ? MET A1 133 PHE A1 146 
AA1 5 PHE A 261 ? ALA A 262 ? PHE A1 261 ALA A1 262 
AA2 1 LYS A 163 ? ASN A 167 ? LYS A1 163 ASN A1 167 
AA2 2 LEU A 150 ? GLU A 155 ? LEU A1 150 GLU A1 155 
AA2 3 THR A 523 ? LEU A 539 ? THR A1 523 LEU A1 539 
AA2 4 MET A 133 ? PHE A 146 ? MET A1 133 PHE A1 146 
AA2 5 CYS A 273 ? ARG A 274 ? CYS A1 273 ARG A1 274 
AA3 1 VAL A 82  ? VAL A 84  ? VAL A1 82  VAL A1 84  
AA3 2 HIS A 102 ? LEU A 111 ? HIS A1 102 LEU A1 111 
AA3 3 THR A 206 ? PHE A 212 ? THR A1 206 PHE A1 212 
AA4 1 VAL A 82  ? VAL A 84  ? VAL A1 82  VAL A1 84  
AA4 2 HIS A 102 ? LEU A 111 ? HIS A1 102 LEU A1 111 
AA4 3 LEU A 498 ? VAL A 502 ? LEU A1 498 VAL A1 502 
AA4 4 LEU A 173 ? LEU A 177 ? LEU A1 173 LEU A1 177 
AA4 5 VAL A 252 ? LEU A 255 ? VAL A1 252 LEU A1 255 
AA5 1 ASP A 215 ? LEU A 218 ? ASP A1 215 LEU A1 218 
AA5 2 ASN A 231 ? GLY A 235 ? ASN A1 231 GLY A1 235 
AA6 1 THR A 276 ? THR A 278 ? THR A1 276 THR A1 278 
AA6 2 ALA A 579 ? ARG A 581 ? ALA A1 579 ARG A1 581 
AA7 1 GLU A 335 ? VAL A 336 ? GLU A1 335 VAL A1 336 
AA7 2 THR A 455 ? ALA A 456 ? THR A1 455 ALA A1 456 
AA8 1 PHE A 345 ? GLU A 346 ? PHE A1 345 GLU A1 346 
AA8 2 PHE A 353 ? LYS A 354 ? PHE A1 353 LYS A1 354 
AA9 1 ARG A 377 ? PHE A 380 ? ARG A1 377 PHE A1 380 
AA9 2 GLU A 396 ? THR A 399 ? GLU A1 396 THR A1 399 
AB1 1 ILE A 415 ? GLN A 416 ? ILE A1 415 GLN A1 416 
AB1 2 VAL A 429 ? LEU A 430 ? VAL A1 429 LEU A1 430 
AB2 1 TRP A 470 ? LYS A 472 ? TRP A1 470 LYS A1 472 
AB2 2 PHE A 488 ? CYS A 490 ? PHE A1 488 CYS A1 490 
AB3 1 MET B 4   ? GLN B 6   ? MET L2 4   GLN L2 6   
AB3 2 VAL B 19  ? VAL B 29  ? VAL L2 19  VAL L2 29  
AB3 3 GLY B 68  ? ILE B 75  ? GLY L2 68  ILE L2 75  
AB3 4 PHE B 62  ? GLY B 66  ? PHE L2 62  GLY L2 66  
AB4 1 PHE B 10  ? THR B 13  ? PHE L2 10  THR L2 13  
AB4 2 THR B 102 ? ILE B 106 ? THR L2 102 ILE L2 106 
AB4 3 LEU B 85  ? GLN B 90  ? LEU L2 85  GLN L2 90  
AB4 4 LEU B 33  ? GLN B 38  ? LEU L2 33  GLN L2 38  
AB4 5 LYS B 45  ? TYR B 49  ? LYS L2 45  TYR L2 49  
AB4 6 ASN B 53  ? ARG B 54  ? ASN L2 53  ARG L2 54  
AB5 1 HIS C 3   ? GLY C 6   ? HIS H2 3   GLY H2 6   
AB5 2 LEU C 20  ? SER C 25  ? LEU H2 20  SER H2 25  
AB5 3 THR C 78  ? GLN C 81  ? THR H2 78  GLN H2 81  
AB5 4 LEU C 70  ? ASP C 73  ? LEU H2 70  ASP H2 73  
AB6 1 SER C 57  ? TYR C 60  ? SER H2 57  TYR H2 60  
AB6 2 GLY C 44  ? PHE C 52  ? GLY H2 44  PHE H2 52  
AB6 3 MET C 34  ? ARG C 40  ? MET H2 34  ARG H2 40  
AB6 4 VAL C 92  ? ARG C 97  ? VAL H2 92  ARG H2 97  
AB6 5 THR C 113 ? LEU C 114 ? THR H2 113 LEU H2 114 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 50  ? N GLU A1 50  O THR A 62  ? O THR A1 62  
AA1 2 3 N LEU A 71  ? N LEU A1 71  O SER A 525 ? O SER A1 525 
AA1 3 4 O LYS A 538 ? O LYS A1 538 N SER A 134 ? N SER A1 134 
AA1 4 5 N ILE A 145 ? N ILE A1 145 O PHE A 261 ? O PHE A1 261 
AA2 1 2 O ASN A 166 ? O ASN A1 166 N THR A 152 ? N THR A1 152 
AA2 2 3 N LYS A 151 ? N LYS A1 151 O TYR A 524 ? O TYR A1 524 
AA2 3 4 O LYS A 538 ? O LYS A1 538 N SER A 134 ? N SER A1 134 
AA2 4 5 N LEU A 136 ? N LEU A1 136 O CYS A 273 ? O CYS A1 273 
AA3 1 2 N VAL A 82  ? N VAL A1 82  O GLN A 104 ? O GLN A1 104 
AA3 2 3 N LEU A 111 ? N LEU A1 111 O THR A 206 ? O THR A1 206 
AA4 1 2 N VAL A 82  ? N VAL A1 82  O GLN A 104 ? O GLN A1 104 
AA4 2 3 N SER A 110 ? N SER A1 110 O VAL A 500 ? O VAL A1 500 
AA4 3 4 O PHE A 499 ? O PHE A1 499 N ALA A 176 ? N ALA A1 176 
AA4 4 5 N LEU A 173 ? N LEU A1 173 O LEU A 255 ? O LEU A1 255 
AA5 1 2 N ASP A 215 ? N ASP A1 215 O GLY A 235 ? O GLY A1 235 
AA6 1 2 N HIS A 277 ? N HIS A1 277 O ALA A 579 ? O ALA A1 579 
AA7 1 2 N GLU A 335 ? N GLU A1 335 O ALA A 456 ? O ALA A1 456 
AA8 1 2 N GLU A 346 ? N GLU A1 346 O PHE A 353 ? O PHE A1 353 
AA9 1 2 N PHE A 380 ? N PHE A1 380 O GLU A 396 ? O GLU A1 396 
AB1 1 2 N ILE A 415 ? N ILE A1 415 O LEU A 430 ? O LEU A1 430 
AB2 1 2 N ASP A 471 ? N ASP A1 471 O CYS A 490 ? O CYS A1 490 
AB3 1 2 N THR B 5   ? N THR L2 5   O LYS B 24  ? O LYS L2 24  
AB3 2 3 N ILE B 21  ? N ILE L2 21  O PHE B 73  ? O PHE L2 73  
AB3 3 4 O THR B 74  ? O THR L2 74  N THR B 63  ? N THR L2 63  
AB4 1 2 N THR B 13  ? N THR L2 13  O GLU B 105 ? O GLU L2 105 
AB4 2 3 O THR B 102 ? O THR L2 102 N TYR B 86  ? N TYR L2 86  
AB4 3 4 O GLN B 89  ? O GLN L2 89  N ALA B 34  ? N ALA L2 34  
AB4 4 5 N TRP B 35  ? N TRP L2 35  O LEU B 47  ? O LEU L2 47  
AB4 5 6 N TYR B 49  ? N TYR L2 49  O ASN B 53  ? O ASN L2 53  
AB5 1 2 N HIS C 3   ? N HIS H2 3   O SER C 25  ? O SER H2 25  
AB5 2 3 N LEU C 20  ? N LEU H2 20  O GLN C 81  ? O GLN H2 81  
AB5 3 4 O THR C 78  ? O THR H2 78  N ASP C 73  ? N ASP H2 73  
AB6 1 2 O SER C 57  ? O SER H2 57  N PHE C 52  ? N PHE H2 52  
AB6 2 3 O GLU C 46  ? O GLU H2 46  N ARG C 38  ? N ARG H2 38  
AB6 3 4 N VAL C 37  ? N VAL H2 37  O PHE C 94  ? O PHE H2 94  
AB6 4 5 N TYR C 93  ? N TYR H2 93  O THR C 113 ? O THR H2 113 
# 
_atom_sites.entry_id                    7M3L 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLY A 1 37  ? 75.108  48.861  -7.073  1.00 25.42  ? 37  GLY A1 N   1 
ATOM 2    C CA  . GLY A 1 37  ? 76.031  49.343  -6.064  1.00 25.87  ? 37  GLY A1 CA  1 
ATOM 3    C C   . GLY A 1 37  ? 77.403  49.707  -6.594  1.00 22.75  ? 37  GLY A1 C   1 
ATOM 4    O O   . GLY A 1 37  ? 77.626  49.727  -7.798  1.00 23.28  ? 37  GLY A1 O   1 
ATOM 5    N N   . VAL A 1 38  ? 78.328  49.977  -5.673  1.00 17.55  ? 38  VAL A1 N   1 
ATOM 6    C CA  . VAL A 1 38  ? 79.665  50.419  -6.052  1.00 13.68  ? 38  VAL A1 CA  1 
ATOM 7    C C   . VAL A 1 38  ? 80.468  49.271  -6.651  1.00 13.18  ? 38  VAL A1 C   1 
ATOM 8    O O   . VAL A 1 38  ? 81.030  49.395  -7.745  1.00 12.50  ? 38  VAL A1 O   1 
ATOM 9    C CB  . VAL A 1 38  ? 80.381  51.035  -4.837  1.00 10.41  ? 38  VAL A1 CB  1 
ATOM 10   C CG1 . VAL A 1 38  ? 81.831  51.322  -5.158  1.00 6.76   ? 38  VAL A1 CG1 1 
ATOM 11   C CG2 . VAL A 1 38  ? 79.678  52.298  -4.402  1.00 8.22   ? 38  VAL A1 CG2 1 
ATOM 12   N N   . GLY A 1 39  ? 80.534  48.141  -5.956  1.00 11.11  ? 39  GLY A1 N   1 
ATOM 13   C CA  . GLY A 1 39  ? 81.343  47.035  -6.418  1.00 11.07  ? 39  GLY A1 CA  1 
ATOM 14   C C   . GLY A 1 39  ? 80.550  45.875  -6.976  1.00 10.87  ? 39  GLY A1 C   1 
ATOM 15   O O   . GLY A 1 39  ? 80.884  44.716  -6.725  1.00 11.49  ? 39  GLY A1 O   1 
ATOM 16   N N   . ILE A 1 40  ? 79.490  46.166  -7.721  1.00 10.42  ? 40  ILE A1 N   1 
ATOM 17   C CA  . ILE A 1 40  ? 78.709  45.156  -8.424  1.00 8.63   ? 40  ILE A1 CA  1 
ATOM 18   C C   . ILE A 1 40  ? 78.681  45.522  -9.898  1.00 7.92   ? 40  ILE A1 C   1 
ATOM 19   O O   . ILE A 1 40  ? 78.282  46.631  -10.264 1.00 8.96   ? 40  ILE A1 O   1 
ATOM 20   C CB  . ILE A 1 40  ? 77.271  45.034  -7.878  1.00 8.21   ? 40  ILE A1 CB  1 
ATOM 21   C CG1 . ILE A 1 40  ? 77.269  44.798  -6.370  1.00 8.30   ? 40  ILE A1 CG1 1 
ATOM 22   C CG2 . ILE A 1 40  ? 76.539  43.911  -8.584  1.00 9.50   ? 40  ILE A1 CG2 1 
ATOM 23   C CD1 . ILE A 1 40  ? 77.838  43.464  -5.963  1.00 9.83   ? 40  ILE A1 CD1 1 
ATOM 24   N N   . SER A 1 41  ? 79.101  44.587  -10.743 1.00 6.04   ? 41  SER A1 N   1 
ATOM 25   C CA  . SER A 1 41  ? 79.140  44.810  -12.178 1.00 4.75   ? 41  SER A1 CA  1 
ATOM 26   C C   . SER A 1 41  ? 77.742  44.697  -12.765 1.00 5.17   ? 41  SER A1 C   1 
ATOM 27   O O   . SER A 1 41  ? 76.950  43.847  -12.354 1.00 4.54   ? 41  SER A1 O   1 
ATOM 28   C CB  . SER A 1 41  ? 80.070  43.809  -12.852 1.00 3.79   ? 41  SER A1 CB  1 
ATOM 29   O OG  . SER A 1 41  ? 79.747  43.686  -14.218 1.00 7.36   ? 41  SER A1 OG  1 
ATOM 30   N N   . THR A 1 42  ? 77.449  45.558  -13.735 1.00 6.52   ? 42  THR A1 N   1 
ATOM 31   C CA  . THR A 1 42  ? 76.105  45.702  -14.270 1.00 6.36   ? 42  THR A1 CA  1 
ATOM 32   C C   . THR A 1 42  ? 75.945  45.158  -15.679 1.00 7.60   ? 42  THR A1 C   1 
ATOM 33   O O   . THR A 1 42  ? 74.942  45.460  -16.327 1.00 11.25  ? 42  THR A1 O   1 
ATOM 34   C CB  . THR A 1 42  ? 75.685  47.174  -14.249 1.00 5.29   ? 42  THR A1 CB  1 
ATOM 35   O OG1 . THR A 1 42  ? 76.699  47.965  -14.874 1.00 7.40   ? 42  THR A1 OG1 1 
ATOM 36   C CG2 . THR A 1 42  ? 75.509  47.653  -12.828 1.00 7.30   ? 42  THR A1 CG2 1 
ATOM 37   N N   . GLY A 1 43  ? 76.892  44.373  -16.178 1.00 7.50   ? 43  GLY A1 N   1 
ATOM 38   C CA  . GLY A 1 43  ? 76.722  43.820  -17.499 1.00 6.84   ? 43  GLY A1 CA  1 
ATOM 39   C C   . GLY A 1 43  ? 77.801  42.827  -17.860 1.00 6.69   ? 43  GLY A1 C   1 
ATOM 40   O O   . GLY A 1 43  ? 78.624  42.439  -17.030 1.00 7.58   ? 43  GLY A1 O   1 
ATOM 41   N N   . THR A 1 44  ? 77.786  42.430  -19.130 1.00 6.36   ? 44  THR A1 N   1 
ATOM 42   C CA  . THR A 1 44  ? 78.669  41.408  -19.663 1.00 6.13   ? 44  THR A1 CA  1 
ATOM 43   C C   . THR A 1 44  ? 79.139  41.836  -21.045 1.00 4.04   ? 44  THR A1 C   1 
ATOM 44   O O   . THR A 1 44  ? 78.337  42.223  -21.895 1.00 4.43   ? 44  THR A1 O   1 
ATOM 45   C CB  . THR A 1 44  ? 77.949  40.047  -19.736 1.00 6.53   ? 44  THR A1 CB  1 
ATOM 46   O OG1 . THR A 1 44  ? 77.778  39.523  -18.416 1.00 8.53   ? 44  THR A1 OG1 1 
ATOM 47   C CG2 . THR A 1 44  ? 78.718  39.038  -20.573 1.00 8.21   ? 44  THR A1 CG2 1 
ATOM 48   N N   . PHE A 1 45  ? 80.449  41.786  -21.250 1.00 2.28   ? 45  PHE A1 N   1 
ATOM 49   C CA  . PHE A 1 45  ? 81.049  41.995  -22.560 1.00 2.92   ? 45  PHE A1 CA  1 
ATOM 50   C C   . PHE A 1 45  ? 80.679  40.826  -23.462 1.00 4.70   ? 45  PHE A1 C   1 
ATOM 51   O O   . PHE A 1 45  ? 80.881  39.669  -23.091 1.00 5.76   ? 45  PHE A1 O   1 
ATOM 52   C CB  . PHE A 1 45  ? 82.563  42.117  -22.396 1.00 2.59   ? 45  PHE A1 CB  1 
ATOM 53   C CG  . PHE A 1 45  ? 83.311  42.422  -23.663 1.00 2.71   ? 45  PHE A1 CG  1 
ATOM 54   C CD1 . PHE A 1 45  ? 83.824  41.408  -24.449 1.00 2.07   ? 45  PHE A1 CD1 1 
ATOM 55   C CD2 . PHE A 1 45  ? 83.564  43.721  -24.026 1.00 2.90   ? 45  PHE A1 CD2 1 
ATOM 56   C CE1 . PHE A 1 45  ? 84.524  41.692  -25.594 1.00 2.05   ? 45  PHE A1 CE1 1 
ATOM 57   C CE2 . PHE A 1 45  ? 84.269  44.009  -25.169 1.00 2.70   ? 45  PHE A1 CE2 1 
ATOM 58   C CZ  . PHE A 1 45  ? 84.744  42.990  -25.953 1.00 3.83   ? 45  PHE A1 CZ  1 
ATOM 59   N N   . ASN A 1 46  ? 80.132  41.115  -24.639 1.00 6.33   ? 46  ASN A1 N   1 
ATOM 60   C CA  . ASN A 1 46  ? 79.789  40.073  -25.601 1.00 6.92   ? 46  ASN A1 CA  1 
ATOM 61   C C   . ASN A 1 46  ? 80.079  40.594  -26.995 1.00 7.45   ? 46  ASN A1 C   1 
ATOM 62   O O   . ASN A 1 46  ? 79.557  41.642  -27.378 1.00 8.65   ? 46  ASN A1 O   1 
ATOM 63   C CB  . ASN A 1 46  ? 78.324  39.664  -25.476 1.00 8.84   ? 46  ASN A1 CB  1 
ATOM 64   C CG  . ASN A 1 46  ? 78.028  38.368  -26.172 1.00 11.10  ? 46  ASN A1 CG  1 
ATOM 65   O OD1 . ASN A 1 46  ? 78.892  37.516  -26.304 1.00 13.08  ? 46  ASN A1 OD1 1 
ATOM 66   N ND2 . ASN A 1 46  ? 76.800  38.207  -26.618 1.00 13.02  ? 46  ASN A1 ND2 1 
ATOM 67   N N   . ASN A 1 47  ? 80.923  39.887  -27.741 1.00 7.66   ? 47  ASN A1 N   1 
ATOM 68   C CA  . ASN A 1 47  ? 81.351  40.348  -29.053 1.00 9.06   ? 47  ASN A1 CA  1 
ATOM 69   C C   . ASN A 1 47  ? 81.436  39.202  -30.044 1.00 10.37  ? 47  ASN A1 C   1 
ATOM 70   O O   . ASN A 1 47  ? 82.400  39.092  -30.803 1.00 11.18  ? 47  ASN A1 O   1 
ATOM 71   C CB  . ASN A 1 47  ? 82.687  41.068  -28.961 1.00 8.91   ? 47  ASN A1 CB  1 
ATOM 72   C CG  . ASN A 1 47  ? 82.841  42.125  -30.009 1.00 10.36  ? 47  ASN A1 CG  1 
ATOM 73   O OD1 . ASN A 1 47  ? 82.643  41.885  -31.189 1.00 13.60  ? 47  ASN A1 OD1 1 
ATOM 74   N ND2 . ASN A 1 47  ? 83.135  43.328  -29.572 1.00 11.65  ? 47  ASN A1 ND2 1 
ATOM 75   N N   . GLN A 1 48  ? 80.443  38.330  -30.069 1.00 11.57  ? 48  GLN A1 N   1 
ATOM 76   C CA  . GLN A 1 48  ? 80.464  37.214  -30.996 1.00 13.41  ? 48  GLN A1 CA  1 
ATOM 77   C C   . GLN A 1 48  ? 79.246  37.252  -31.902 1.00 14.38  ? 48  GLN A1 C   1 
ATOM 78   O O   . GLN A 1 48  ? 78.127  37.485  -31.448 1.00 14.16  ? 48  GLN A1 O   1 
ATOM 79   C CB  . GLN A 1 48  ? 80.531  35.892  -30.255 1.00 16.28  ? 48  GLN A1 CB  1 
ATOM 80   C CG  . GLN A 1 48  ? 79.727  35.858  -29.004 1.00 22.68  ? 48  GLN A1 CG  1 
ATOM 81   C CD  . GLN A 1 48  ? 79.938  34.588  -28.245 1.00 26.53  ? 48  GLN A1 CD  1 
ATOM 82   O OE1 . GLN A 1 48  ? 80.978  33.951  -28.372 1.00 30.18  ? 48  GLN A1 OE1 1 
ATOM 83   N NE2 . GLN A 1 48  ? 78.951  34.197  -27.455 1.00 28.79  ? 48  GLN A1 NE2 1 
ATOM 84   N N   . THR A 1 49  ? 79.481  37.024  -33.186 1.00 15.76  ? 49  THR A1 N   1 
ATOM 85   C CA  . THR A 1 49  ? 78.422  36.953  -34.175 1.00 17.65  ? 49  THR A1 CA  1 
ATOM 86   C C   . THR A 1 49  ? 77.905  35.526  -34.255 1.00 16.10  ? 49  THR A1 C   1 
ATOM 87   O O   . THR A 1 49  ? 78.672  34.577  -34.431 1.00 16.67  ? 49  THR A1 O   1 
ATOM 88   C CB  . THR A 1 49  ? 78.930  37.418  -35.539 1.00 19.63  ? 49  THR A1 CB  1 
ATOM 89   O OG1 . THR A 1 49  ? 79.251  38.811  -35.477 1.00 19.55  ? 49  THR A1 OG1 1 
ATOM 90   C CG2 . THR A 1 49  ? 77.893  37.199  -36.622 1.00 21.10  ? 49  THR A1 CG2 1 
ATOM 91   N N   . GLU A 1 50  ? 76.590  35.382  -34.116 1.00 16.79  ? 50  GLU A1 N   1 
ATOM 92   C CA  . GLU A 1 50  ? 75.968  34.091  -33.875 1.00 18.60  ? 50  GLU A1 CA  1 
ATOM 93   C C   . GLU A 1 50  ? 74.976  33.774  -34.980 1.00 16.86  ? 50  GLU A1 C   1 
ATOM 94   O O   . GLU A 1 50  ? 73.941  34.433  -35.089 1.00 17.21  ? 50  GLU A1 O   1 
ATOM 95   C CB  . GLU A 1 50  ? 75.270  34.107  -32.514 1.00 23.98  ? 50  GLU A1 CB  1 
ATOM 96   C CG  . GLU A 1 50  ? 76.244  34.264  -31.358 1.00 32.39  ? 50  GLU A1 CG  1 
ATOM 97   C CD  . GLU A 1 50  ? 75.561  34.504  -30.028 1.00 36.87  ? 50  GLU A1 CD  1 
ATOM 98   O OE1 . GLU A 1 50  ? 74.335  34.745  -30.026 1.00 40.95  ? 50  GLU A1 OE1 1 
ATOM 99   O OE2 . GLU A 1 50  ? 76.250  34.452  -28.987 1.00 38.16  ? 50  GLU A1 OE2 1 
ATOM 100  N N   . PHE A 1 51  ? 75.277  32.752  -35.777 1.00 14.92  ? 51  PHE A1 N   1 
ATOM 101  C CA  . PHE A 1 51  ? 74.447  32.341  -36.906 1.00 14.31  ? 51  PHE A1 CA  1 
ATOM 102  C C   . PHE A 1 51  ? 73.489  31.258  -36.436 1.00 15.51  ? 51  PHE A1 C   1 
ATOM 103  O O   . PHE A 1 51  ? 73.917  30.150  -36.106 1.00 17.47  ? 51  PHE A1 O   1 
ATOM 104  C CB  . PHE A 1 51  ? 75.296  31.812  -38.054 1.00 12.58  ? 51  PHE A1 CB  1 
ATOM 105  C CG  . PHE A 1 51  ? 75.985  32.872  -38.843 1.00 13.63  ? 51  PHE A1 CG  1 
ATOM 106  C CD1 . PHE A 1 51  ? 77.089  33.519  -38.333 1.00 14.55  ? 51  PHE A1 CD1 1 
ATOM 107  C CD2 . PHE A 1 51  ? 75.550  33.196  -40.112 1.00 14.57  ? 51  PHE A1 CD2 1 
ATOM 108  C CE1 . PHE A 1 51  ? 77.730  34.481  -39.053 1.00 15.83  ? 51  PHE A1 CE1 1 
ATOM 109  C CE2 . PHE A 1 51  ? 76.198  34.162  -40.843 1.00 15.57  ? 51  PHE A1 CE2 1 
ATOM 110  C CZ  . PHE A 1 51  ? 77.291  34.806  -40.309 1.00 16.12  ? 51  PHE A1 CZ  1 
ATOM 111  N N   . LYS A 1 52  ? 72.201  31.570  -36.411 1.00 15.52  ? 52  LYS A1 N   1 
ATOM 112  C CA  . LYS A 1 52  ? 71.177  30.602  -36.033 1.00 15.94  ? 52  LYS A1 CA  1 
ATOM 113  C C   . LYS A 1 52  ? 70.460  30.173  -37.303 1.00 15.29  ? 52  LYS A1 C   1 
ATOM 114  O O   . LYS A 1 52  ? 69.637  30.902  -37.847 1.00 15.56  ? 52  LYS A1 O   1 
ATOM 115  C CB  . LYS A 1 52  ? 70.213  31.191  -35.017 1.00 18.92  ? 52  LYS A1 CB  1 
ATOM 116  C CG  . LYS A 1 52  ? 69.309  30.166  -34.379 1.00 23.27  ? 52  LYS A1 CG  1 
ATOM 117  C CD  . LYS A 1 52  ? 67.876  30.653  -34.300 1.00 28.52  ? 52  LYS A1 CD  1 
ATOM 118  C CE  . LYS A 1 52  ? 67.781  32.012  -33.629 1.00 32.82  ? 52  LYS A1 CE  1 
ATOM 119  N NZ  . LYS A 1 52  ? 66.369  32.439  -33.439 1.00 36.60  ? 52  LYS A1 NZ  1 
ATOM 120  N N   . PHE A 1 53  ? 70.779  28.978  -37.782 1.00 15.64  ? 53  PHE A1 N   1 
ATOM 121  C CA  . PHE A 1 53  ? 70.180  28.473  -39.012 1.00 16.17  ? 53  PHE A1 CA  1 
ATOM 122  C C   . PHE A 1 53  ? 68.768  28.010  -38.712 1.00 17.82  ? 53  PHE A1 C   1 
ATOM 123  O O   . PHE A 1 53  ? 68.547  26.889  -38.252 1.00 19.57  ? 53  PHE A1 O   1 
ATOM 124  C CB  . PHE A 1 53  ? 71.018  27.346  -39.597 1.00 14.51  ? 53  PHE A1 CB  1 
ATOM 125  C CG  . PHE A 1 53  ? 72.384  27.774  -40.018 1.00 12.94  ? 53  PHE A1 CG  1 
ATOM 126  C CD1 . PHE A 1 53  ? 72.566  28.497  -41.181 1.00 13.92  ? 53  PHE A1 CD1 1 
ATOM 127  C CD2 . PHE A 1 53  ? 73.489  27.457  -39.250 1.00 12.92  ? 53  PHE A1 CD2 1 
ATOM 128  C CE1 . PHE A 1 53  ? 73.825  28.897  -41.573 1.00 15.02  ? 53  PHE A1 CE1 1 
ATOM 129  C CE2 . PHE A 1 53  ? 74.748  27.855  -39.637 1.00 15.51  ? 53  PHE A1 CE2 1 
ATOM 130  C CZ  . PHE A 1 53  ? 74.915  28.574  -40.801 1.00 15.93  ? 53  PHE A1 CZ  1 
ATOM 131  N N   . LEU A 1 54  ? 67.801  28.872  -38.986 1.00 20.56  ? 54  LEU A1 N   1 
ATOM 132  C CA  . LEU A 1 54  ? 66.394  28.542  -38.825 1.00 23.33  ? 54  LEU A1 CA  1 
ATOM 133  C C   . LEU A 1 54  ? 65.917  27.812  -40.082 1.00 29.34  ? 54  LEU A1 C   1 
ATOM 134  O O   . LEU A 1 54  ? 66.718  27.252  -40.837 1.00 32.19  ? 54  LEU A1 O   1 
ATOM 135  C CB  . LEU A 1 54  ? 65.603  29.797  -38.459 1.00 19.00  ? 54  LEU A1 CB  1 
ATOM 136  C CG  . LEU A 1 54  ? 65.555  31.081  -39.283 1.00 17.25  ? 54  LEU A1 CG  1 
ATOM 137  C CD1 . LEU A 1 54  ? 64.413  31.077  -40.266 1.00 15.90  ? 54  LEU A1 CD1 1 
ATOM 138  C CD2 . LEU A 1 54  ? 65.426  32.269  -38.360 1.00 16.53  ? 54  LEU A1 CD2 1 
ATOM 139  N N   . GLU A 1 55  ? 64.598  27.754  -40.292 1.00 35.20  ? 55  GLU A1 N   1 
ATOM 140  C CA  . GLU A 1 55  ? 63.960  26.938  -41.327 1.00 38.79  ? 55  GLU A1 CA  1 
ATOM 141  C C   . GLU A 1 55  ? 64.385  27.293  -42.749 1.00 35.73  ? 55  GLU A1 C   1 
ATOM 142  O O   . GLU A 1 55  ? 65.088  28.286  -42.953 1.00 35.01  ? 55  GLU A1 O   1 
ATOM 143  C CB  . GLU A 1 55  ? 62.437  27.041  -41.197 1.00 47.67  ? 55  GLU A1 CB  1 
ATOM 144  C CG  . GLU A 1 55  ? 61.890  28.462  -41.025 1.00 57.03  ? 55  GLU A1 CG  1 
ATOM 145  C CD  . GLU A 1 55  ? 61.759  29.243  -42.326 1.00 61.98  ? 55  GLU A1 CD  1 
ATOM 146  O OE1 . GLU A 1 55  ? 61.673  28.619  -43.403 1.00 65.03  ? 55  GLU A1 OE1 1 
ATOM 147  O OE2 . GLU A 1 55  ? 61.743  30.488  -42.266 1.00 64.72  ? 55  GLU A1 OE2 1 
ATOM 148  N N   . ASN A 1 56  ? 63.879  26.534  -43.729 1.00 32.24  ? 56  ASN A1 N   1 
ATOM 149  C CA  . ASN A 1 56  ? 64.545  26.253  -45.001 1.00 32.40  ? 56  ASN A1 CA  1 
ATOM 150  C C   . ASN A 1 56  ? 64.976  27.487  -45.781 1.00 29.05  ? 56  ASN A1 C   1 
ATOM 151  O O   . ASN A 1 56  ? 64.145  28.222  -46.321 1.00 29.62  ? 56  ASN A1 O   1 
ATOM 152  C CB  . ASN A 1 56  ? 63.622  25.400  -45.879 1.00 36.97  ? 56  ASN A1 CB  1 
ATOM 153  C CG  . ASN A 1 56  ? 64.383  24.457  -46.805 1.00 40.53  ? 56  ASN A1 CG  1 
ATOM 154  O OD1 . ASN A 1 56  ? 65.490  24.757  -47.252 1.00 42.95  ? 56  ASN A1 OD1 1 
ATOM 155  N ND2 . ASN A 1 56  ? 63.779  23.316  -47.105 1.00 43.05  ? 56  ASN A1 ND2 1 
ATOM 156  N N   . GLY A 1 57  ? 66.289  27.709  -45.823 1.00 25.58  ? 57  GLY A1 N   1 
ATOM 157  C CA  . GLY A 1 57  ? 66.895  28.763  -46.599 1.00 23.96  ? 57  GLY A1 CA  1 
ATOM 158  C C   . GLY A 1 57  ? 67.408  29.946  -45.810 1.00 22.54  ? 57  GLY A1 C   1 
ATOM 159  O O   . GLY A 1 57  ? 68.292  30.648  -46.304 1.00 25.36  ? 57  GLY A1 O   1 
ATOM 160  N N   . TRP A 1 58  ? 66.905  30.183  -44.604 1.00 19.16  ? 58  TRP A1 N   1 
ATOM 161  C CA  . TRP A 1 58  ? 67.104  31.448  -43.913 1.00 16.48  ? 58  TRP A1 CA  1 
ATOM 162  C C   . TRP A 1 58  ? 67.972  31.273  -42.679 1.00 16.42  ? 58  TRP A1 C   1 
ATOM 163  O O   . TRP A 1 58  ? 67.880  30.257  -41.988 1.00 16.97  ? 58  TRP A1 O   1 
ATOM 164  C CB  . TRP A 1 58  ? 65.770  32.062  -43.512 1.00 17.57  ? 58  TRP A1 CB  1 
ATOM 165  C CG  . TRP A 1 58  ? 64.979  32.539  -44.652 1.00 20.24  ? 58  TRP A1 CG  1 
ATOM 166  C CD1 . TRP A 1 58  ? 64.049  31.843  -45.346 1.00 20.39  ? 58  TRP A1 CD1 1 
ATOM 167  C CD2 . TRP A 1 58  ? 65.044  33.830  -45.246 1.00 21.23  ? 58  TRP A1 CD2 1 
ATOM 168  N NE1 . TRP A 1 58  ? 63.524  32.621  -46.343 1.00 21.54  ? 58  TRP A1 NE1 1 
ATOM 169  C CE2 . TRP A 1 58  ? 64.122  33.849  -46.300 1.00 21.37  ? 58  TRP A1 CE2 1 
ATOM 170  C CE3 . TRP A 1 58  ? 65.793  34.975  -44.988 1.00 21.71  ? 58  TRP A1 CE3 1 
ATOM 171  C CZ2 . TRP A 1 58  ? 63.930  34.965  -47.094 1.00 21.32  ? 58  TRP A1 CZ2 1 
ATOM 172  C CZ3 . TRP A 1 58  ? 65.604  36.076  -45.773 1.00 21.71  ? 58  TRP A1 CZ3 1 
ATOM 173  C CH2 . TRP A 1 58  ? 64.680  36.069  -46.814 1.00 20.93  ? 58  TRP A1 CH2 1 
ATOM 174  N N   . VAL A 1 59  ? 68.803  32.276  -42.410 1.00 16.37  ? 59  VAL A1 N   1 
ATOM 175  C CA  . VAL A 1 59  ? 69.677  32.329  -41.245 1.00 16.55  ? 59  VAL A1 CA  1 
ATOM 176  C C   . VAL A 1 59  ? 69.245  33.526  -40.411 1.00 15.62  ? 59  VAL A1 C   1 
ATOM 177  O O   . VAL A 1 59  ? 68.669  34.481  -40.939 1.00 13.78  ? 59  VAL A1 O   1 
ATOM 178  C CB  . VAL A 1 59  ? 71.157  32.451  -41.666 1.00 17.97  ? 59  VAL A1 CB  1 
ATOM 179  C CG1 . VAL A 1 59  ? 72.100  32.105  -40.538 1.00 19.89  ? 59  VAL A1 CG1 1 
ATOM 180  C CG2 . VAL A 1 59  ? 71.441  31.562  -42.817 1.00 19.17  ? 59  VAL A1 CG2 1 
ATOM 181  N N   . GLU A 1 60  ? 69.490  33.463  -39.111 1.00 15.79  ? 60  GLU A1 N   1 
ATOM 182  C CA  . GLU A 1 60  ? 69.269  34.570  -38.193 1.00 17.30  ? 60  GLU A1 CA  1 
ATOM 183  C C   . GLU A 1 60  ? 70.653  34.987  -37.703 1.00 14.97  ? 60  GLU A1 C   1 
ATOM 184  O O   . GLU A 1 60  ? 71.244  34.343  -36.838 1.00 14.58  ? 60  GLU A1 O   1 
ATOM 185  C CB  . GLU A 1 60  ? 68.343  34.134  -37.065 1.00 21.63  ? 60  GLU A1 CB  1 
ATOM 186  C CG  . GLU A 1 60  ? 68.256  35.019  -35.838 1.00 30.18  ? 60  GLU A1 CG  1 
ATOM 187  C CD  . GLU A 1 60  ? 67.136  36.029  -35.919 1.00 36.11  ? 60  GLU A1 CD  1 
ATOM 188  O OE1 . GLU A 1 60  ? 66.853  36.667  -34.886 1.00 38.64  ? 60  GLU A1 OE1 1 
ATOM 189  O OE2 . GLU A 1 60  ? 66.549  36.195  -37.004 1.00 40.29  ? 60  GLU A1 OE2 1 
ATOM 190  N N   . ILE A 1 61  ? 71.192  36.044  -38.302 1.00 10.46  ? 61  ILE A1 N   1 
ATOM 191  C CA  . ILE A 1 61  ? 72.497  36.544  -37.897 1.00 6.42   ? 61  ILE A1 CA  1 
ATOM 192  C C   . ILE A 1 61  ? 72.323  37.554  -36.776 1.00 5.59   ? 61  ILE A1 C   1 
ATOM 193  O O   . ILE A 1 61  ? 71.742  38.625  -36.973 1.00 4.87   ? 61  ILE A1 O   1 
ATOM 194  C CB  . ILE A 1 61  ? 73.226  37.169  -39.091 1.00 5.94   ? 61  ILE A1 CB  1 
ATOM 195  C CG1 . ILE A 1 61  ? 73.084  36.282  -40.319 1.00 6.35   ? 61  ILE A1 CG1 1 
ATOM 196  C CG2 . ILE A 1 61  ? 74.673  37.404  -38.762 1.00 6.04   ? 61  ILE A1 CG2 1 
ATOM 197  C CD1 . ILE A 1 61  ? 73.568  36.929  -41.566 1.00 6.60   ? 61  ILE A1 CD1 1 
ATOM 198  N N   . THR A 1 62  ? 72.819  37.219  -35.592 1.00 5.35   ? 62  THR A1 N   1 
ATOM 199  C CA  . THR A 1 62  ? 72.775  38.108  -34.438 1.00 4.60   ? 62  THR A1 CA  1 
ATOM 200  C C   . THR A 1 62  ? 74.188  38.589  -34.181 1.00 3.75   ? 62  THR A1 C   1 
ATOM 201  O O   . THR A 1 62  ? 75.012  37.841  -33.651 1.00 2.96   ? 62  THR A1 O   1 
ATOM 202  C CB  . THR A 1 62  ? 72.219  37.402  -33.209 1.00 3.79   ? 62  THR A1 CB  1 
ATOM 203  O OG1 . THR A 1 62  ? 71.030  36.687  -33.562 1.00 3.55   ? 62  THR A1 OG1 1 
ATOM 204  C CG2 . THR A 1 62  ? 71.903  38.397  -32.130 1.00 4.12   ? 62  THR A1 CG2 1 
ATOM 205  N N   . ALA A 1 63  ? 74.472  39.822  -34.561 1.00 2.67   ? 63  ALA A1 N   1 
ATOM 206  C CA  . ALA A 1 63  ? 75.804  40.389  -34.437 1.00 2.88   ? 63  ALA A1 CA  1 
ATOM 207  C C   . ALA A 1 63  ? 75.885  41.157  -33.127 1.00 4.52   ? 63  ALA A1 C   1 
ATOM 208  O O   . ALA A 1 63  ? 75.389  42.279  -33.028 1.00 6.21   ? 63  ALA A1 O   1 
ATOM 209  C CB  . ALA A 1 63  ? 76.116  41.293  -35.623 1.00 2.00   ? 63  ALA A1 CB  1 
ATOM 210  N N   . ASN A 1 64  ? 76.504  40.549  -32.126 1.00 5.24   ? 64  ASN A1 N   1 
ATOM 211  C CA  . ASN A 1 64  ? 76.810  41.234  -30.886 1.00 4.64   ? 64  ASN A1 CA  1 
ATOM 212  C C   . ASN A 1 64  ? 78.073  42.053  -31.056 1.00 4.57   ? 64  ASN A1 C   1 
ATOM 213  O O   . ASN A 1 64  ? 78.956  41.709  -31.841 1.00 6.56   ? 64  ASN A1 O   1 
ATOM 214  C CB  . ASN A 1 64  ? 76.998  40.249  -29.742 1.00 6.06   ? 64  ASN A1 CB  1 
ATOM 215  C CG  . ASN A 1 64  ? 75.735  39.534  -29.385 1.00 8.59   ? 64  ASN A1 CG  1 
ATOM 216  O OD1 . ASN A 1 64  ? 75.020  39.940  -28.476 1.00 10.95  ? 64  ASN A1 OD1 1 
ATOM 217  N ND2 . ASN A 1 64  ? 75.452  38.450  -30.087 1.00 9.38   ? 64  ASN A1 ND2 1 
ATOM 218  N N   . SER A 1 65  ? 78.148  43.152  -30.315 1.00 3.73   ? 65  SER A1 N   1 
ATOM 219  C CA  . SER A 1 65  ? 79.291  44.046  -30.371 1.00 4.27   ? 65  SER A1 CA  1 
ATOM 220  C C   . SER A 1 65  ? 79.307  44.867  -29.102 1.00 5.12   ? 65  SER A1 C   1 
ATOM 221  O O   . SER A 1 65  ? 78.276  45.399  -28.697 1.00 8.01   ? 65  SER A1 O   1 
ATOM 222  C CB  . SER A 1 65  ? 79.233  44.966  -31.581 1.00 4.25   ? 65  SER A1 CB  1 
ATOM 223  O OG  . SER A 1 65  ? 80.505  45.482  -31.886 1.00 6.39   ? 65  SER A1 OG  1 
ATOM 224  N N   . SER A 1 66  ? 80.470  44.955  -28.471 1.00 5.35   ? 66  SER A1 N   1 
ATOM 225  C CA  . SER A 1 66  ? 80.587  45.664  -27.212 1.00 4.89   ? 66  SER A1 CA  1 
ATOM 226  C C   . SER A 1 66  ? 81.945  46.335  -27.151 1.00 5.10   ? 66  SER A1 C   1 
ATOM 227  O O   . SER A 1 66  ? 82.948  45.733  -27.533 1.00 6.86   ? 66  SER A1 O   1 
ATOM 228  C CB  . SER A 1 66  ? 80.405  44.710  -26.039 1.00 4.42   ? 66  SER A1 CB  1 
ATOM 229  O OG  . SER A 1 66  ? 80.921  45.280  -24.862 1.00 5.09   ? 66  SER A1 OG  1 
ATOM 230  N N   . ARG A 1 67  ? 81.973  47.583  -26.693 1.00 4.36   ? 67  ARG A1 N   1 
ATOM 231  C CA  . ARG A 1 67  ? 83.168  48.408  -26.717 1.00 4.50   ? 67  ARG A1 CA  1 
ATOM 232  C C   . ARG A 1 67  ? 83.379  49.046  -25.354 1.00 5.73   ? 67  ARG A1 C   1 
ATOM 233  O O   . ARG A 1 67  ? 82.483  49.066  -24.513 1.00 5.35   ? 67  ARG A1 O   1 
ATOM 234  C CB  . ARG A 1 67  ? 83.070  49.514  -27.771 1.00 4.57   ? 67  ARG A1 CB  1 
ATOM 235  C CG  . ARG A 1 67  ? 82.819  49.047  -29.177 1.00 4.03   ? 67  ARG A1 CG  1 
ATOM 236  C CD  . ARG A 1 67  ? 84.099  48.764  -29.909 1.00 4.21   ? 67  ARG A1 CD  1 
ATOM 237  N NE  . ARG A 1 67  ? 83.836  48.330  -31.271 1.00 5.30   ? 67  ARG A1 NE  1 
ATOM 238  C CZ  . ARG A 1 67  ? 83.669  47.065  -31.612 1.00 8.04   ? 67  ARG A1 CZ  1 
ATOM 239  N NH1 . ARG A 1 67  ? 83.432  46.733  -32.863 1.00 8.85   ? 67  ARG A1 NH1 1 
ATOM 240  N NH2 . ARG A 1 67  ? 83.747  46.128  -30.691 1.00 8.86   ? 67  ARG A1 NH2 1 
ATOM 241  N N   . LEU A 1 68  ? 84.577  49.576  -25.143 1.00 7.17   ? 68  LEU A1 N   1 
ATOM 242  C CA  . LEU A 1 68  ? 84.868  50.411  -23.985 1.00 6.78   ? 68  LEU A1 CA  1 
ATOM 243  C C   . LEU A 1 68  ? 85.034  51.839  -24.473 1.00 6.15   ? 68  LEU A1 C   1 
ATOM 244  O O   . LEU A 1 68  ? 86.002  52.150  -25.169 1.00 6.70   ? 68  LEU A1 O   1 
ATOM 245  C CB  . LEU A 1 68  ? 86.122  49.943  -23.253 1.00 4.34   ? 68  LEU A1 CB  1 
ATOM 246  C CG  . LEU A 1 68  ? 86.677  50.850  -22.155 1.00 2.77   ? 68  LEU A1 CG  1 
ATOM 247  C CD1 . LEU A 1 68  ? 85.815  50.831  -20.936 1.00 2.34   ? 68  LEU A1 CD1 1 
ATOM 248  C CD2 . LEU A 1 68  ? 88.063  50.404  -21.796 1.00 2.00   ? 68  LEU A1 CD2 1 
ATOM 249  N N   . VAL A 1 69  ? 84.090  52.699  -24.117 1.00 5.94   ? 69  VAL A1 N   1 
ATOM 250  C CA  . VAL A 1 69  ? 84.019  54.053  -24.644 1.00 5.23   ? 69  VAL A1 CA  1 
ATOM 251  C C   . VAL A 1 69  ? 84.594  54.999  -23.603 1.00 6.18   ? 69  VAL A1 C   1 
ATOM 252  O O   . VAL A 1 69  ? 84.196  54.960  -22.436 1.00 6.89   ? 69  VAL A1 O   1 
ATOM 253  C CB  . VAL A 1 69  ? 82.579  54.422  -25.013 1.00 4.13   ? 69  VAL A1 CB  1 
ATOM 254  C CG1 . VAL A 1 69  ? 82.547  55.694  -25.746 1.00 4.56   ? 69  VAL A1 CG1 1 
ATOM 255  C CG2 . VAL A 1 69  ? 81.994  53.342  -25.873 1.00 3.56   ? 69  VAL A1 CG2 1 
ATOM 256  N N   . HIS A 1 70  ? 85.547  55.823  -24.014 1.00 5.18   ? 70  HIS A1 N   1 
ATOM 257  C CA  . HIS A 1 70  ? 86.241  56.739  -23.119 1.00 4.76   ? 70  HIS A1 CA  1 
ATOM 258  C C   . HIS A 1 70  ? 85.748  58.148  -23.401 1.00 6.04   ? 70  HIS A1 C   1 
ATOM 259  O O   . HIS A 1 70  ? 85.952  58.676  -24.496 1.00 6.99   ? 70  HIS A1 O   1 
ATOM 260  C CB  . HIS A 1 70  ? 87.750  56.641  -23.306 1.00 4.38   ? 70  HIS A1 CB  1 
ATOM 261  C CG  . HIS A 1 70  ? 88.518  57.725  -22.619 1.00 5.06   ? 70  HIS A1 CG  1 
ATOM 262  N ND1 . HIS A 1 70  ? 88.844  58.913  -23.235 1.00 4.67   ? 70  HIS A1 ND1 1 
ATOM 263  C CD2 . HIS A 1 70  ? 89.029  57.798  -21.371 1.00 4.95   ? 70  HIS A1 CD2 1 
ATOM 264  C CE1 . HIS A 1 70  ? 89.517  59.671  -22.393 1.00 5.40   ? 70  HIS A1 CE1 1 
ATOM 265  N NE2 . HIS A 1 70  ? 89.641  59.020  -21.253 1.00 6.05   ? 70  HIS A1 NE2 1 
ATOM 266  N N   . LEU A 1 71  ? 85.124  58.766  -22.408 1.00 5.72   ? 71  LEU A1 N   1 
ATOM 267  C CA  . LEU A 1 71  ? 84.489  60.066  -22.556 1.00 4.61   ? 71  LEU A1 CA  1 
ATOM 268  C C   . LEU A 1 71  ? 85.053  61.007  -21.508 1.00 5.96   ? 71  LEU A1 C   1 
ATOM 269  O O   . LEU A 1 71  ? 85.064  60.676  -20.322 1.00 7.56   ? 71  LEU A1 O   1 
ATOM 270  C CB  . LEU A 1 71  ? 82.977  59.937  -22.395 1.00 3.28   ? 71  LEU A1 CB  1 
ATOM 271  C CG  . LEU A 1 71  ? 82.120  61.191  -22.309 1.00 3.01   ? 71  LEU A1 CG  1 
ATOM 272  C CD1 . LEU A 1 71  ? 82.044  61.910  -23.618 1.00 2.99   ? 71  LEU A1 CD1 1 
ATOM 273  C CD2 . LEU A 1 71  ? 80.770  60.783  -21.875 1.00 3.79   ? 71  LEU A1 CD2 1 
ATOM 274  N N   . ASN A 1 72  ? 85.523  62.168  -21.939 1.00 7.11   ? 72  ASN A1 N   1 
ATOM 275  C CA  . ASN A 1 72  ? 85.916  63.213  -21.012 1.00 8.21   ? 72  ASN A1 CA  1 
ATOM 276  C C   . ASN A 1 72  ? 85.017  64.428  -21.184 1.00 8.75   ? 72  ASN A1 C   1 
ATOM 277  O O   . ASN A 1 72  ? 84.292  64.552  -22.172 1.00 11.70  ? 72  ASN A1 O   1 
ATOM 278  C CB  . ASN A 1 72  ? 87.390  63.586  -21.182 1.00 10.58  ? 72  ASN A1 CB  1 
ATOM 279  C CG  . ASN A 1 72  ? 87.816  63.614  -22.615 1.00 11.45  ? 72  ASN A1 CG  1 
ATOM 280  O OD1 . ASN A 1 72  ? 87.000  63.461  -23.518 1.00 14.85  ? 72  ASN A1 OD1 1 
ATOM 281  N ND2 . ASN A 1 72  ? 89.107  63.791  -22.841 1.00 12.24  ? 72  ASN A1 ND2 1 
ATOM 282  N N   . MET A 1 73  ? 85.067  65.309  -20.188 1.00 8.87   ? 73  MET A1 N   1 
ATOM 283  C CA  . MET A 1 73  ? 84.096  66.381  -20.053 1.00 7.45   ? 73  MET A1 CA  1 
ATOM 284  C C   . MET A 1 73  ? 84.269  67.411  -21.169 1.00 7.65   ? 73  MET A1 C   1 
ATOM 285  O O   . MET A 1 73  ? 85.367  67.569  -21.707 1.00 9.83   ? 73  MET A1 O   1 
ATOM 286  C CB  . MET A 1 73  ? 84.240  67.038  -18.683 1.00 5.93   ? 73  MET A1 CB  1 
ATOM 287  C CG  . MET A 1 73  ? 85.572  67.679  -18.429 1.00 6.05   ? 73  MET A1 CG  1 
ATOM 288  S SD  . MET A 1 73  ? 85.575  68.636  -16.912 1.00 9.12   ? 73  MET A1 SD  1 
ATOM 289  C CE  . MET A 1 73  ? 86.847  69.827  -17.288 1.00 9.01   ? 73  MET A1 CE  1 
ATOM 290  N N   . PRO A 1 74  ? 83.189  68.078  -21.580 1.00 6.82   ? 74  PRO A1 N   1 
ATOM 291  C CA  . PRO A 1 74  ? 83.280  69.013  -22.705 1.00 5.25   ? 74  PRO A1 CA  1 
ATOM 292  C C   . PRO A 1 74  ? 84.092  70.249  -22.356 1.00 6.64   ? 74  PRO A1 C   1 
ATOM 293  O O   . PRO A 1 74  ? 84.238  70.634  -21.196 1.00 4.00   ? 74  PRO A1 O   1 
ATOM 294  C CB  . PRO A 1 74  ? 81.820  69.372  -22.988 1.00 4.91   ? 74  PRO A1 CB  1 
ATOM 295  C CG  . PRO A 1 74  ? 81.085  68.987  -21.779 1.00 5.21   ? 74  PRO A1 CG  1 
ATOM 296  C CD  . PRO A 1 74  ? 81.787  67.811  -21.227 1.00 7.22   ? 74  PRO A1 CD  1 
ATOM 297  N N   . GLU A 1 75  ? 84.637  70.868  -23.407 1.00 10.56  ? 75  GLU A1 N   1 
ATOM 298  C CA  . GLU A 1 75  ? 85.449  72.068  -23.235 1.00 15.12  ? 75  GLU A1 CA  1 
ATOM 299  C C   . GLU A 1 75  ? 84.612  73.252  -22.782 1.00 14.99  ? 75  GLU A1 C   1 
ATOM 300  O O   . GLU A 1 75  ? 85.134  74.170  -22.142 1.00 15.23  ? 75  GLU A1 O   1 
ATOM 301  C CB  . GLU A 1 75  ? 86.173  72.397  -24.538 1.00 19.51  ? 75  GLU A1 CB  1 
ATOM 302  C CG  . GLU A 1 75  ? 85.249  72.517  -25.743 1.00 27.20  ? 75  GLU A1 CG  1 
ATOM 303  C CD  . GLU A 1 75  ? 85.884  73.237  -26.915 1.00 31.06  ? 75  GLU A1 CD  1 
ATOM 304  O OE1 . GLU A 1 75  ? 86.672  72.608  -27.650 1.00 30.42  ? 75  GLU A1 OE1 1 
ATOM 305  O OE2 . GLU A 1 75  ? 85.585  74.433  -27.106 1.00 34.83  ? 75  GLU A1 OE2 1 
ATOM 306  N N   . SER A 1 76  ? 83.322  73.248  -23.099 1.00 15.07  ? 76  SER A1 N   1 
ATOM 307  C CA  . SER A 1 76  ? 82.406  74.282  -22.658 1.00 15.69  ? 76  SER A1 CA  1 
ATOM 308  C C   . SER A 1 76  ? 81.020  73.670  -22.592 1.00 15.34  ? 76  SER A1 C   1 
ATOM 309  O O   . SER A 1 76  ? 80.658  72.820  -23.406 1.00 14.89  ? 76  SER A1 O   1 
ATOM 310  C CB  . SER A 1 76  ? 82.434  75.495  -23.594 1.00 17.03  ? 76  SER A1 CB  1 
ATOM 311  O OG  . SER A 1 76  ? 81.243  76.254  -23.490 1.00 20.06  ? 76  SER A1 OG  1 
ATOM 312  N N   . GLU A 1 77  ? 80.246  74.110  -21.609 1.00 14.66  ? 77  GLU A1 N   1 
ATOM 313  C CA  . GLU A 1 77  ? 78.921  73.569  -21.342 1.00 14.76  ? 77  GLU A1 CA  1 
ATOM 314  C C   . GLU A 1 77  ? 77.825  74.446  -21.933 1.00 12.72  ? 77  GLU A1 C   1 
ATOM 315  O O   . GLU A 1 77  ? 76.711  74.506  -21.417 1.00 11.65  ? 77  GLU A1 O   1 
ATOM 316  C CB  . GLU A 1 77  ? 78.714  73.402  -19.845 1.00 17.55  ? 77  GLU A1 CB  1 
ATOM 317  C CG  . GLU A 1 77  ? 79.589  72.341  -19.232 1.00 21.39  ? 77  GLU A1 CG  1 
ATOM 318  C CD  . GLU A 1 77  ? 78.881  71.017  -19.111 1.00 23.18  ? 77  GLU A1 CD  1 
ATOM 319  O OE1 . GLU A 1 77  ? 79.563  69.976  -18.989 1.00 24.69  ? 77  GLU A1 OE1 1 
ATOM 320  O OE2 . GLU A 1 77  ? 77.635  71.024  -19.142 1.00 25.93  ? 77  GLU A1 OE2 1 
ATOM 321  N N   . ASN A 1 78  ? 78.132  75.132  -23.026 1.00 10.45  ? 78  ASN A1 N   1 
ATOM 322  C CA  . ASN A 1 78  ? 77.193  76.019  -23.688 1.00 10.79  ? 78  ASN A1 CA  1 
ATOM 323  C C   . ASN A 1 78  ? 76.957  75.539  -25.107 1.00 11.46  ? 78  ASN A1 C   1 
ATOM 324  O O   . ASN A 1 78  ? 77.762  74.787  -25.657 1.00 14.10  ? 78  ASN A1 O   1 
ATOM 325  C CB  . ASN A 1 78  ? 77.712  77.449  -23.719 1.00 11.36  ? 78  ASN A1 CB  1 
ATOM 326  C CG  . ASN A 1 78  ? 78.131  77.942  -22.366 1.00 12.94  ? 78  ASN A1 CG  1 
ATOM 327  O OD1 . ASN A 1 78  ? 77.381  77.845  -21.397 1.00 12.83  ? 78  ASN A1 OD1 1 
ATOM 328  N ND2 . ASN A 1 78  ? 79.340  78.475  -22.283 1.00 14.77  ? 78  ASN A1 ND2 1 
ATOM 329  N N   . TYR A 1 79  ? 75.851  75.971  -25.691 1.00 10.68  ? 79  TYR A1 N   1 
ATOM 330  C CA  . TYR A 1 79  ? 75.577  75.711  -27.098 1.00 9.61   ? 79  TYR A1 CA  1 
ATOM 331  C C   . TYR A 1 79  ? 76.054  76.924  -27.877 1.00 10.67  ? 79  TYR A1 C   1 
ATOM 332  O O   . TYR A 1 79  ? 75.399  77.967  -27.880 1.00 13.71  ? 79  TYR A1 O   1 
ATOM 333  C CB  . TYR A 1 79  ? 74.091  75.466  -27.329 1.00 8.21   ? 79  TYR A1 CB  1 
ATOM 334  C CG  . TYR A 1 79  ? 73.536  74.189  -26.746 1.00 7.71   ? 79  TYR A1 CG  1 
ATOM 335  C CD1 . TYR A 1 79  ? 73.246  74.090  -25.402 1.00 8.03   ? 79  TYR A1 CD1 1 
ATOM 336  C CD2 . TYR A 1 79  ? 73.269  73.100  -27.550 1.00 6.24   ? 79  TYR A1 CD2 1 
ATOM 337  C CE1 . TYR A 1 79  ? 72.738  72.944  -24.874 1.00 7.31   ? 79  TYR A1 CE1 1 
ATOM 338  C CE2 . TYR A 1 79  ? 72.753  71.944  -27.025 1.00 5.45   ? 79  TYR A1 CE2 1 
ATOM 339  C CZ  . TYR A 1 79  ? 72.494  71.875  -25.685 1.00 6.14   ? 79  TYR A1 CZ  1 
ATOM 340  O OH  . TYR A 1 79  ? 71.980  70.728  -25.142 1.00 4.11   ? 79  TYR A1 OH  1 
ATOM 341  N N   . ARG A 1 80  ? 77.204  76.808  -28.528 1.00 9.54   ? 80  ARG A1 N   1 
ATOM 342  C CA  . ARG A 1 80  ? 77.678  77.891  -29.366 1.00 8.63   ? 80  ARG A1 CA  1 
ATOM 343  C C   . ARG A 1 80  ? 76.976  77.858  -30.712 1.00 9.83   ? 80  ARG A1 C   1 
ATOM 344  O O   . ARG A 1 80  ? 76.317  76.892  -31.068 1.00 10.45  ? 80  ARG A1 O   1 
ATOM 345  C CB  . ARG A 1 80  ? 79.175  77.795  -29.599 1.00 8.96   ? 80  ARG A1 CB  1 
ATOM 346  C CG  . ARG A 1 80  ? 80.029  77.494  -28.414 1.00 11.27  ? 80  ARG A1 CG  1 
ATOM 347  C CD  . ARG A 1 80  ? 81.426  77.925  -28.768 1.00 15.09  ? 80  ARG A1 CD  1 
ATOM 348  N NE  . ARG A 1 80  ? 82.401  77.628  -27.735 1.00 17.37  ? 80  ARG A1 NE  1 
ATOM 349  C CZ  . ARG A 1 80  ? 83.525  78.313  -27.569 1.00 20.13  ? 80  ARG A1 CZ  1 
ATOM 350  N NH1 . ARG A 1 80  ? 83.796  79.338  -28.364 1.00 20.97  ? 80  ARG A1 NH1 1 
ATOM 351  N NH2 . ARG A 1 80  ? 84.371  77.981  -26.609 1.00 21.58  ? 80  ARG A1 NH2 1 
ATOM 352  N N   . ARG A 1 81  ? 77.128  78.936  -31.473 1.00 10.66  ? 81  ARG A1 N   1 
ATOM 353  C CA  . ARG A 1 81  ? 76.697  78.971  -32.871 1.00 10.83  ? 81  ARG A1 CA  1 
ATOM 354  C C   . ARG A 1 81  ? 77.890  79.483  -33.668 1.00 11.19  ? 81  ARG A1 C   1 
ATOM 355  O O   . ARG A 1 81  ? 78.086  80.690  -33.808 1.00 14.14  ? 81  ARG A1 O   1 
ATOM 356  C CB  . ARG A 1 81  ? 75.471  79.838  -33.076 1.00 11.22  ? 81  ARG A1 CB  1 
ATOM 357  C CG  . ARG A 1 81  ? 74.978  79.841  -34.496 1.00 12.84  ? 81  ARG A1 CG  1 
ATOM 358  C CD  . ARG A 1 81  ? 73.898  80.873  -34.690 1.00 15.64  ? 81  ARG A1 CD  1 
ATOM 359  N NE  . ARG A 1 81  ? 74.439  82.168  -35.072 1.00 18.83  ? 81  ARG A1 NE  1 
ATOM 360  C CZ  . ARG A 1 81  ? 74.345  83.259  -34.324 1.00 22.00  ? 81  ARG A1 CZ  1 
ATOM 361  N NH1 . ARG A 1 81  ? 73.732  83.207  -33.156 1.00 24.12  ? 81  ARG A1 NH1 1 
ATOM 362  N NH2 . ARG A 1 81  ? 74.862  84.401  -34.746 1.00 23.60  ? 81  ARG A1 NH2 1 
ATOM 363  N N   . VAL A 1 82  ? 78.682  78.564  -34.168 1.00 9.89   ? 82  VAL A1 N   1 
ATOM 364  C CA  . VAL A 1 82  ? 79.934  78.881  -34.832 1.00 7.82   ? 82  VAL A1 CA  1 
ATOM 365  C C   . VAL A 1 82  ? 79.702  78.877  -36.330 1.00 7.11   ? 82  VAL A1 C   1 
ATOM 366  O O   . VAL A 1 82  ? 79.112  77.942  -36.876 1.00 7.04   ? 82  VAL A1 O   1 
ATOM 367  C CB  . VAL A 1 82  ? 81.018  77.869  -34.431 1.00 7.89   ? 82  VAL A1 CB  1 
ATOM 368  C CG1 . VAL A 1 82  ? 82.329  78.196  -35.099 1.00 7.83   ? 82  VAL A1 CG1 1 
ATOM 369  C CG2 . VAL A 1 82  ? 81.175  77.848  -32.941 1.00 7.07   ? 82  VAL A1 CG2 1 
ATOM 370  N N   . VAL A 1 83  ? 80.170  79.918  -37.002 1.00 7.37   ? 83  VAL A1 N   1 
ATOM 371  C CA  . VAL A 1 83  ? 80.094  80.025  -38.451 1.00 6.15   ? 83  VAL A1 CA  1 
ATOM 372  C C   . VAL A 1 83  ? 81.475  79.713  -38.998 1.00 6.85   ? 83  VAL A1 C   1 
ATOM 373  O O   . VAL A 1 83  ? 82.445  80.417  -38.695 1.00 8.05   ? 83  VAL A1 O   1 
ATOM 374  C CB  . VAL A 1 83  ? 79.622  81.410  -38.899 1.00 3.28   ? 83  VAL A1 CB  1 
ATOM 375  C CG1 . VAL A 1 83  ? 79.761  81.540  -40.391 1.00 4.00   ? 83  VAL A1 CG1 1 
ATOM 376  C CG2 . VAL A 1 83  ? 78.188  81.623  -38.488 1.00 2.64   ? 83  VAL A1 CG2 1 
ATOM 377  N N   . VAL A 1 84  ? 81.576  78.650  -39.782 1.00 6.81   ? 84  VAL A1 N   1 
ATOM 378  C CA  . VAL A 1 84  ? 82.823  78.320  -40.457 1.00 7.63   ? 84  VAL A1 CA  1 
ATOM 379  C C   . VAL A 1 84  ? 82.888  79.109  -41.752 1.00 9.16   ? 84  VAL A1 C   1 
ATOM 380  O O   . VAL A 1 84  ? 81.919  79.155  -42.513 1.00 8.86   ? 84  VAL A1 O   1 
ATOM 381  C CB  . VAL A 1 84  ? 82.922  76.813  -40.709 1.00 7.02   ? 84  VAL A1 CB  1 
ATOM 382  C CG1 . VAL A 1 84  ? 84.244  76.466  -41.345 1.00 5.39   ? 84  VAL A1 CG1 1 
ATOM 383  C CG2 . VAL A 1 84  ? 82.763  76.074  -39.408 1.00 5.67   ? 84  VAL A1 CG2 1 
ATOM 384  N N   . ASN A 1 85  ? 84.027  79.749  -41.998 1.00 12.64  ? 85  ASN A1 N   1 
ATOM 385  C CA  . ASN A 1 85  ? 84.137  80.677  -43.118 1.00 15.39  ? 85  ASN A1 CA  1 
ATOM 386  C C   . ASN A 1 85  ? 85.604  80.684  -43.548 1.00 14.66  ? 85  ASN A1 C   1 
ATOM 387  O O   . ASN A 1 85  ? 86.483  81.064  -42.775 1.00 15.55  ? 85  ASN A1 O   1 
ATOM 388  C CB  . ASN A 1 85  ? 83.658  82.060  -42.728 1.00 17.60  ? 85  ASN A1 CB  1 
ATOM 389  C CG  . ASN A 1 85  ? 83.486  82.986  -43.913 1.00 20.49  ? 85  ASN A1 CG  1 
ATOM 390  O OD1 . ASN A 1 85  ? 84.423  83.244  -44.659 1.00 22.47  ? 85  ASN A1 OD1 1 
ATOM 391  N ND2 . ASN A 1 85  ? 82.276  83.496  -44.084 1.00 23.65  ? 85  ASN A1 ND2 1 
ATOM 392  N N   . ASN A 1 86  ? 85.849  80.250  -44.777 1.00 15.82  ? 86  ASN A1 N   1 
ATOM 393  C CA  . ASN A 1 86  ? 87.145  80.427  -45.412 1.00 18.34  ? 86  ASN A1 CA  1 
ATOM 394  C C   . ASN A 1 86  ? 86.983  81.367  -46.601 1.00 19.55  ? 86  ASN A1 C   1 
ATOM 395  O O   . ASN A 1 86  ? 86.213  81.085  -47.521 1.00 15.86  ? 86  ASN A1 O   1 
ATOM 396  C CB  . ASN A 1 86  ? 87.740  79.088  -45.851 1.00 18.13  ? 86  ASN A1 CB  1 
ATOM 397  C CG  . ASN A 1 86  ? 86.772  78.249  -46.646 1.00 18.37  ? 86  ASN A1 CG  1 
ATOM 398  O OD1 . ASN A 1 86  ? 85.580  78.244  -46.371 1.00 19.33  ? 86  ASN A1 OD1 1 
ATOM 399  N ND2 . ASN A 1 86  ? 87.278  77.545  -47.646 1.00 18.26  ? 86  ASN A1 ND2 1 
ATOM 400  N N   . MET A 1 87  ? 87.665  82.502  -46.561 1.00 22.47  ? 87  MET A1 N   1 
ATOM 401  C CA  . MET A 1 87  ? 87.962  83.234  -47.779 1.00 24.02  ? 87  MET A1 CA  1 
ATOM 402  C C   . MET A 1 87  ? 89.476  83.292  -47.899 1.00 22.72  ? 87  MET A1 C   1 
ATOM 403  O O   . MET A 1 87  ? 90.107  84.336  -47.718 1.00 20.72  ? 87  MET A1 O   1 
ATOM 404  C CB  . MET A 1 87  ? 87.346  84.632  -47.761 1.00 27.35  ? 87  MET A1 CB  1 
ATOM 405  C CG  . MET A 1 87  ? 85.961  84.711  -47.169 1.00 31.76  ? 87  MET A1 CG  1 
ATOM 406  S SD  . MET A 1 87  ? 84.653  84.184  -48.288 1.00 37.20  ? 87  MET A1 SD  1 
ATOM 407  C CE  . MET A 1 87  ? 83.200  84.706  -47.379 1.00 35.40  ? 87  MET A1 CE  1 
ATOM 408  N N   . ASP A 1 88  ? 90.053  82.146  -48.224 1.00 21.69  ? 88  ASP A1 N   1 
ATOM 409  C CA  . ASP A 1 88  ? 91.401  82.043  -48.754 1.00 22.69  ? 88  ASP A1 CA  1 
ATOM 410  C C   . ASP A 1 88  ? 91.502  81.018  -49.856 1.00 21.03  ? 88  ASP A1 C   1 
ATOM 411  O O   . ASP A 1 88  ? 92.403  81.118  -50.696 1.00 20.93  ? 88  ASP A1 O   1 
ATOM 412  C CB  . ASP A 1 88  ? 92.401  81.693  -47.643 1.00 27.21  ? 88  ASP A1 CB  1 
ATOM 413  C CG  . ASP A 1 88  ? 91.921  80.567  -46.740 1.00 31.60  ? 88  ASP A1 CG  1 
ATOM 414  O OD1 . ASP A 1 88  ? 92.354  80.533  -45.571 1.00 33.30  ? 88  ASP A1 OD1 1 
ATOM 415  O OD2 . ASP A 1 88  ? 91.116  79.720  -47.171 1.00 34.23  ? 88  ASP A1 OD2 1 
ATOM 416  N N   . LYS A 1 89  ? 90.602  80.042  -49.880 1.00 18.99  ? 89  LYS A1 N   1 
ATOM 417  C CA  . LYS A 1 89  ? 90.572  78.996  -50.878 1.00 17.85  ? 89  LYS A1 CA  1 
ATOM 418  C C   . LYS A 1 89  ? 89.410  79.137  -51.834 1.00 17.78  ? 89  LYS A1 C   1 
ATOM 419  O O   . LYS A 1 89  ? 89.573  78.857  -53.015 1.00 16.04  ? 89  LYS A1 O   1 
ATOM 420  C CB  . LYS A 1 89  ? 90.511  77.624  -50.200 1.00 18.17  ? 89  LYS A1 CB  1 
ATOM 421  C CG  . LYS A 1 89  ? 91.784  77.275  -49.459 1.00 20.51  ? 89  LYS A1 CG  1 
ATOM 422  C CD  . LYS A 1 89  ? 91.644  76.005  -48.660 1.00 24.60  ? 89  LYS A1 CD  1 
ATOM 423  C CE  . LYS A 1 89  ? 92.925  75.687  -47.917 1.00 27.10  ? 89  LYS A1 CE  1 
ATOM 424  N NZ  . LYS A 1 89  ? 93.984  75.205  -48.842 1.00 30.71  ? 89  LYS A1 NZ  1 
ATOM 425  N N   . THR A 1 90  ? 88.255  79.587  -51.365 1.00 19.39  ? 90  THR A1 N   1 
ATOM 426  C CA  . THR A 1 90  ? 87.144  79.858  -52.259 1.00 20.50  ? 90  THR A1 CA  1 
ATOM 427  C C   . THR A 1 90  ? 87.111  81.306  -52.721 1.00 19.51  ? 90  THR A1 C   1 
ATOM 428  O O   . THR A 1 90  ? 86.339  81.635  -53.625 1.00 20.95  ? 90  THR A1 O   1 
ATOM 429  C CB  . THR A 1 90  ? 85.815  79.482  -51.597 1.00 21.65  ? 90  THR A1 CB  1 
ATOM 430  O OG1 . THR A 1 90  ? 84.816  79.326  -52.605 1.00 24.59  ? 90  THR A1 OG1 1 
ATOM 431  C CG2 . THR A 1 90  ? 85.366  80.549  -50.630 1.00 21.71  ? 90  THR A1 CG2 1 
ATOM 432  N N   . ALA A 1 91  ? 87.943  82.172  -52.142 1.00 17.36  ? 91  ALA A1 N   1 
ATOM 433  C CA  . ALA A 1 91  ? 88.050  83.542  -52.624 1.00 14.94  ? 91  ALA A1 CA  1 
ATOM 434  C C   . ALA A 1 91  ? 88.942  83.654  -53.848 1.00 14.25  ? 91  ALA A1 C   1 
ATOM 435  O O   . ALA A 1 91  ? 88.726  84.546  -54.671 1.00 16.01  ? 91  ALA A1 O   1 
ATOM 436  C CB  . ALA A 1 91  ? 88.576  84.457  -51.519 1.00 14.48  ? 91  ALA A1 CB  1 
ATOM 437  N N   . VAL A 1 92  ? 89.942  82.781  -53.973 1.00 11.76  ? 92  VAL A1 N   1 
ATOM 438  C CA  . VAL A 1 92  ? 90.668  82.627  -55.225 1.00 9.66   ? 92  VAL A1 CA  1 
ATOM 439  C C   . VAL A 1 92  ? 89.711  82.106  -56.285 1.00 12.15  ? 92  VAL A1 C   1 
ATOM 440  O O   . VAL A 1 92  ? 89.025  81.099  -56.083 1.00 13.82  ? 92  VAL A1 O   1 
ATOM 441  C CB  . VAL A 1 92  ? 91.856  81.670  -55.040 1.00 8.24   ? 92  VAL A1 CB  1 
ATOM 442  C CG1 . VAL A 1 92  ? 92.479  81.327  -56.374 1.00 7.88   ? 92  VAL A1 CG1 1 
ATOM 443  C CG2 . VAL A 1 92  ? 92.886  82.277  -54.124 1.00 7.68   ? 92  VAL A1 CG2 1 
ATOM 444  N N   . ASN A 1 93  ? 89.631  82.805  -57.413 1.00 15.08  ? 93  ASN A1 N   1 
ATOM 445  C CA  . ASN A 1 93  ? 88.731  82.379  -58.472 1.00 17.34  ? 93  ASN A1 CA  1 
ATOM 446  C C   . ASN A 1 93  ? 89.338  81.182  -59.187 1.00 17.79  ? 93  ASN A1 C   1 
ATOM 447  O O   . ASN A 1 93  ? 90.466  81.250  -59.680 1.00 20.62  ? 93  ASN A1 O   1 
ATOM 448  C CB  . ASN A 1 93  ? 88.438  83.519  -59.445 1.00 19.51  ? 93  ASN A1 CB  1 
ATOM 449  C CG  . ASN A 1 93  ? 89.663  84.295  -59.827 1.00 21.91  ? 93  ASN A1 CG  1 
ATOM 450  O OD1 . ASN A 1 93  ? 90.744  84.086  -59.282 1.00 23.73  ? 93  ASN A1 OD1 1 
ATOM 451  N ND2 . ASN A 1 93  ? 89.507  85.198  -60.785 1.00 23.27  ? 93  ASN A1 ND2 1 
ATOM 452  N N   . GLY A 1 94  ? 88.605  80.079  -59.214 1.00 17.77  ? 94  GLY A1 N   1 
ATOM 453  C CA  . GLY A 1 94  ? 89.095  78.895  -59.876 1.00 18.23  ? 94  GLY A1 CA  1 
ATOM 454  C C   . GLY A 1 94  ? 88.767  77.622  -59.139 1.00 17.61  ? 94  GLY A1 C   1 
ATOM 455  O O   . GLY A 1 94  ? 88.633  76.563  -59.754 1.00 17.09  ? 94  GLY A1 O   1 
ATOM 456  N N   . ASN A 1 95  ? 88.625  77.707  -57.822 1.00 15.45  ? 95  ASN A1 N   1 
ATOM 457  C CA  . ASN A 1 95  ? 88.234  76.564  -57.003 1.00 13.70  ? 95  ASN A1 CA  1 
ATOM 458  C C   . ASN A 1 95  ? 87.006  76.978  -56.207 1.00 13.48  ? 95  ASN A1 C   1 
ATOM 459  O O   . ASN A 1 95  ? 87.101  77.433  -55.067 1.00 12.37  ? 95  ASN A1 O   1 
ATOM 460  C CB  . ASN A 1 95  ? 89.374  76.095  -56.109 1.00 14.98  ? 95  ASN A1 CB  1 
ATOM 461  C CG  . ASN A 1 95  ? 90.172  77.231  -55.549 1.00 16.73  ? 95  ASN A1 CG  1 
ATOM 462  O OD1 . ASN A 1 95  ? 89.889  78.385  -55.828 1.00 17.76  ? 95  ASN A1 OD1 1 
ATOM 463  N ND2 . ASN A 1 95  ? 91.177  76.917  -54.751 1.00 18.01  ? 95  ASN A1 ND2 1 
ATOM 464  N N   . MET A 1 96  ? 85.844  76.826  -56.831 1.00 12.51  ? 96  MET A1 N   1 
ATOM 465  C CA  . MET A 1 96  ? 84.572  76.963  -56.148 1.00 10.43  ? 96  MET A1 CA  1 
ATOM 466  C C   . MET A 1 96  ? 84.223  75.718  -55.360 1.00 9.94   ? 96  MET A1 C   1 
ATOM 467  O O   . MET A 1 96  ? 83.483  75.807  -54.377 1.00 10.75  ? 96  MET A1 O   1 
ATOM 468  C CB  . MET A 1 96  ? 83.461  77.243  -57.160 1.00 9.95   ? 96  MET A1 CB  1 
ATOM 469  C CG  . MET A 1 96  ? 83.833  78.272  -58.189 1.00 11.54  ? 96  MET A1 CG  1 
ATOM 470  S SD  . MET A 1 96  ? 85.015  77.641  -59.385 1.00 11.56  ? 96  MET A1 SD  1 
ATOM 471  C CE  . MET A 1 96  ? 83.977  76.672  -60.457 1.00 9.13   ? 96  MET A1 CE  1 
ATOM 472  N N   . ALA A 1 97  ? 84.751  74.564  -55.768 1.00 9.97   ? 97  ALA A1 N   1 
ATOM 473  C CA  . ALA A 1 97  ? 84.480  73.290  -55.123 1.00 9.71   ? 97  ALA A1 CA  1 
ATOM 474  C C   . ALA A 1 97  ? 85.238  73.109  -53.820 1.00 8.95   ? 97  ALA A1 C   1 
ATOM 475  O O   . ALA A 1 97  ? 85.031  72.099  -53.144 1.00 9.73   ? 97  ALA A1 O   1 
ATOM 476  C CB  . ALA A 1 97  ? 84.817  72.143  -56.071 1.00 9.27   ? 97  ALA A1 CB  1 
ATOM 477  N N   . LEU A 1 98  ? 86.106  74.049  -53.455 1.00 8.29   ? 98  LEU A1 N   1 
ATOM 478  C CA  . LEU A 1 98  ? 86.747  74.061  -52.150 1.00 7.98   ? 98  LEU A1 CA  1 
ATOM 479  C C   . LEU A 1 98  ? 85.963  74.866  -51.128 1.00 8.16   ? 98  LEU A1 C   1 
ATOM 480  O O   . LEU A 1 98  ? 86.554  75.401  -50.187 1.00 7.86   ? 98  LEU A1 O   1 
ATOM 481  C CB  . LEU A 1 98  ? 88.167  74.608  -52.258 1.00 8.81   ? 98  LEU A1 CB  1 
ATOM 482  C CG  . LEU A 1 98  ? 89.180  73.829  -53.085 1.00 10.01  ? 98  LEU A1 CG  1 
ATOM 483  C CD1 . LEU A 1 98  ? 90.563  74.275  -52.696 1.00 11.41  ? 98  LEU A1 CD1 1 
ATOM 484  C CD2 . LEU A 1 98  ? 89.039  72.343  -52.891 1.00 9.94   ? 98  LEU A1 CD2 1 
ATOM 485  N N   . ASP A 1 99  ? 84.653  74.967  -51.298 1.00 9.17   ? 99  ASP A1 N   1 
ATOM 486  C CA  . ASP A 1 99  ? 83.805  75.756  -50.417 1.00 10.07  ? 99  ASP A1 CA  1 
ATOM 487  C C   . ASP A 1 99  ? 83.307  74.882  -49.281 1.00 10.41  ? 99  ASP A1 C   1 
ATOM 488  O O   . ASP A 1 99  ? 82.710  73.830  -49.517 1.00 11.26  ? 99  ASP A1 O   1 
ATOM 489  C CB  . ASP A 1 99  ? 82.632  76.332  -51.200 1.00 11.81  ? 99  ASP A1 CB  1 
ATOM 490  C CG  . ASP A 1 99  ? 81.625  77.010  -50.317 1.00 15.23  ? 99  ASP A1 CG  1 
ATOM 491  O OD1 . ASP A 1 99  ? 81.906  78.120  -49.827 1.00 17.04  ? 99  ASP A1 OD1 1 
ATOM 492  O OD2 . ASP A 1 99  ? 80.540  76.436  -50.108 1.00 15.72  ? 99  ASP A1 OD2 1 
ATOM 493  N N   . ASP A 1 100 ? 83.560  75.303  -48.050 1.00 9.66   ? 100 ASP A1 N   1 
ATOM 494  C CA  . ASP A 1 100 ? 82.964  74.686  -46.875 1.00 7.86   ? 100 ASP A1 CA  1 
ATOM 495  C C   . ASP A 1 100 ? 82.537  75.744  -45.871 1.00 7.84   ? 100 ASP A1 C   1 
ATOM 496  O O   . ASP A 1 100 ? 82.813  75.649  -44.677 1.00 6.55   ? 100 ASP A1 O   1 
ATOM 497  C CB  . ASP A 1 100 ? 83.904  73.650  -46.260 1.00 8.17   ? 100 ASP A1 CB  1 
ATOM 498  C CG  . ASP A 1 100 ? 85.290  74.185  -46.000 1.00 9.39   ? 100 ASP A1 CG  1 
ATOM 499  O OD1 . ASP A 1 100 ? 85.553  75.361  -46.309 1.00 9.65   ? 100 ASP A1 OD1 1 
ATOM 500  O OD2 . ASP A 1 100 ? 86.134  73.409  -45.512 1.00 8.40   ? 100 ASP A1 OD2 1 
ATOM 501  N N   . ILE A 1 101 ? 81.866  76.776  -46.367 1.00 8.94   ? 101 ILE A1 N   1 
ATOM 502  C CA  . ILE A 1 101 ? 81.244  77.781  -45.517 1.00 9.76   ? 101 ILE A1 CA  1 
ATOM 503  C C   . ILE A 1 101 ? 79.919  77.227  -45.028 1.00 8.86   ? 101 ILE A1 C   1 
ATOM 504  O O   . ILE A 1 101 ? 79.031  76.922  -45.829 1.00 10.86  ? 101 ILE A1 O   1 
ATOM 505  C CB  . ILE A 1 101 ? 81.045  79.098  -46.270 1.00 10.25  ? 101 ILE A1 CB  1 
ATOM 506  C CG1 . ILE A 1 101 ? 82.390  79.767  -46.513 1.00 12.01  ? 101 ILE A1 CG1 1 
ATOM 507  C CG2 . ILE A 1 101 ? 80.129  80.025  -45.503 1.00 9.18   ? 101 ILE A1 CG2 1 
ATOM 508  C CD1 . ILE A 1 101 ? 82.292  81.056  -47.263 1.00 14.14  ? 101 ILE A1 CD1 1 
ATOM 509  N N   . HIS A 1 102 ? 79.790  77.072  -43.718 1.00 7.48   ? 102 HIS A1 N   1 
ATOM 510  C CA  . HIS A 1 102 ? 78.551  76.622  -43.123 1.00 6.29   ? 102 HIS A1 CA  1 
ATOM 511  C C   . HIS A 1 102 ? 78.414  77.278  -41.761 1.00 6.45   ? 102 HIS A1 C   1 
ATOM 512  O O   . HIS A 1 102 ? 79.341  77.921  -41.269 1.00 7.61   ? 102 HIS A1 O   1 
ATOM 513  C CB  . HIS A 1 102 ? 78.508  75.094  -43.045 1.00 6.15   ? 102 HIS A1 CB  1 
ATOM 514  C CG  . HIS A 1 102 ? 79.594  74.492  -42.216 1.00 6.50   ? 102 HIS A1 CG  1 
ATOM 515  N ND1 . HIS A 1 102 ? 80.835  74.194  -42.726 1.00 7.05   ? 102 HIS A1 ND1 1 
ATOM 516  C CD2 . HIS A 1 102 ? 79.613  74.097  -40.925 1.00 7.20   ? 102 HIS A1 CD2 1 
ATOM 517  C CE1 . HIS A 1 102 ? 81.580  73.657  -41.778 1.00 7.58   ? 102 HIS A1 CE1 1 
ATOM 518  N NE2 . HIS A 1 102 ? 80.861  73.588  -40.675 1.00 7.15   ? 102 HIS A1 NE2 1 
ATOM 519  N N   . ALA A 1 103 ? 77.242  77.128  -41.158 1.00 7.18   ? 103 ALA A1 N   1 
ATOM 520  C CA  . ALA A 1 103 ? 77.005  77.593  -39.804 1.00 6.86   ? 103 ALA A1 CA  1 
ATOM 521  C C   . ALA A 1 103 ? 76.420  76.430  -39.033 1.00 8.00   ? 103 ALA A1 C   1 
ATOM 522  O O   . ALA A 1 103 ? 75.541  75.737  -39.545 1.00 9.12   ? 103 ALA A1 O   1 
ATOM 523  C CB  . ALA A 1 103 ? 76.055  78.789  -39.773 1.00 6.88   ? 103 ALA A1 CB  1 
ATOM 524  N N   . GLN A 1 104 ? 76.915  76.200  -37.826 1.00 8.53   ? 104 GLN A1 N   1 
ATOM 525  C CA  . GLN A 1 104 ? 76.525  75.029  -37.067 1.00 8.44   ? 104 GLN A1 CA  1 
ATOM 526  C C   . GLN A 1 104 ? 76.448  75.362  -35.588 1.00 8.53   ? 104 GLN A1 C   1 
ATOM 527  O O   . GLN A 1 104 ? 76.822  76.449  -35.150 1.00 8.00   ? 104 GLN A1 O   1 
ATOM 528  C CB  . GLN A 1 104 ? 77.500  73.882  -37.301 1.00 8.96   ? 104 GLN A1 CB  1 
ATOM 529  C CG  . GLN A 1 104 ? 78.845  74.088  -36.680 1.00 9.48   ? 104 GLN A1 CG  1 
ATOM 530  C CD  . GLN A 1 104 ? 79.751  72.936  -36.966 1.00 11.15  ? 104 GLN A1 CD  1 
ATOM 531  O OE1 . GLN A 1 104 ? 79.368  72.002  -37.657 1.00 11.40  ? 104 GLN A1 OE1 1 
ATOM 532  N NE2 . GLN A 1 104 ? 80.956  72.986  -36.444 1.00 9.86   ? 104 GLN A1 NE2 1 
ATOM 533  N N   . ILE A 1 105 ? 75.951  74.404  -34.815 1.00 7.66   ? 105 ILE A1 N   1 
ATOM 534  C CA  . ILE A 1 105 ? 75.802  74.545  -33.375 1.00 5.37   ? 105 ILE A1 CA  1 
ATOM 535  C C   . ILE A 1 105 ? 76.598  73.435  -32.710 1.00 5.23   ? 105 ILE A1 C   1 
ATOM 536  O O   . ILE A 1 105 ? 76.228  72.262  -32.800 1.00 5.95   ? 105 ILE A1 O   1 
ATOM 537  C CB  . ILE A 1 105 ? 74.333  74.504  -32.945 1.00 3.77   ? 105 ILE A1 CB  1 
ATOM 538  C CG1 . ILE A 1 105 ? 73.628  75.758  -33.434 1.00 3.16   ? 105 ILE A1 CG1 1 
ATOM 539  C CG2 . ILE A 1 105 ? 74.212  74.402  -31.442 1.00 2.15   ? 105 ILE A1 CG2 1 
ATOM 540  C CD1 . ILE A 1 105 ? 72.227  75.842  -33.029 1.00 2.36   ? 105 ILE A1 CD1 1 
ATOM 541  N N   . VAL A 1 106 ? 77.693  73.794  -32.049 1.00 4.75   ? 106 VAL A1 N   1 
ATOM 542  C CA  . VAL A 1 106 ? 78.482  72.810  -31.319 1.00 3.81   ? 106 VAL A1 CA  1 
ATOM 543  C C   . VAL A 1 106 ? 77.913  72.656  -29.915 1.00 4.54   ? 106 VAL A1 C   1 
ATOM 544  O O   . VAL A 1 106 ? 77.819  73.622  -29.154 1.00 4.69   ? 106 VAL A1 O   1 
ATOM 545  C CB  . VAL A 1 106 ? 79.969  73.187  -31.296 1.00 2.97   ? 106 VAL A1 CB  1 
ATOM 546  C CG1 . VAL A 1 106 ? 80.628  72.726  -32.559 1.00 4.61   ? 106 VAL A1 CG1 1 
ATOM 547  C CG2 . VAL A 1 106 ? 80.128  74.655  -31.228 1.00 3.13   ? 106 VAL A1 CG2 1 
ATOM 548  N N   . THR A 1 107 ? 77.536  71.444  -29.576 1.00 4.33   ? 107 THR A1 N   1 
ATOM 549  C CA  . THR A 1 107 ? 76.858  71.086  -28.347 1.00 4.33   ? 107 THR A1 CA  1 
ATOM 550  C C   . THR A 1 107 ? 77.847  70.478  -27.366 1.00 4.29   ? 107 THR A1 C   1 
ATOM 551  O O   . THR A 1 107 ? 78.897  69.971  -27.765 1.00 5.75   ? 107 THR A1 O   1 
ATOM 552  C CB  . THR A 1 107 ? 75.749  70.085  -28.647 1.00 4.45   ? 107 THR A1 CB  1 
ATOM 553  O OG1 . THR A 1 107 ? 76.325  68.916  -29.218 1.00 5.72   ? 107 THR A1 OG1 1 
ATOM 554  C CG2 . THR A 1 107 ? 74.802  70.642  -29.660 1.00 5.05   ? 107 THR A1 CG2 1 
ATOM 555  N N   . PRO A 1 108 ? 77.556  70.515  -26.063 1.00 4.01   ? 108 PRO A1 N   1 
ATOM 556  C CA  . PRO A 1 108 ? 78.377  69.767  -25.106 1.00 3.55   ? 108 PRO A1 CA  1 
ATOM 557  C C   . PRO A 1 108 ? 78.114  68.270  -25.082 1.00 4.82   ? 108 PRO A1 C   1 
ATOM 558  O O   . PRO A 1 108 ? 78.733  67.568  -24.277 1.00 4.72   ? 108 PRO A1 O   1 
ATOM 559  C CB  . PRO A 1 108 ? 77.992  70.405  -23.769 1.00 3.29   ? 108 PRO A1 CB  1 
ATOM 560  C CG  . PRO A 1 108 ? 76.637  70.939  -23.997 1.00 4.48   ? 108 PRO A1 CG  1 
ATOM 561  C CD  . PRO A 1 108 ? 76.658  71.454  -25.377 1.00 4.18   ? 108 PRO A1 CD  1 
ATOM 562  N N   . TRP A 1 109 ? 77.230  67.755  -25.928 1.00 5.95   ? 109 TRP A1 N   1 
ATOM 563  C CA  . TRP A 1 109 ? 76.837  66.359  -25.884 1.00 7.12   ? 109 TRP A1 CA  1 
ATOM 564  C C   . TRP A 1 109 ? 77.640  65.553  -26.887 1.00 8.36   ? 109 TRP A1 C   1 
ATOM 565  O O   . TRP A 1 109 ? 77.921  66.017  -27.990 1.00 11.19  ? 109 TRP A1 O   1 
ATOM 566  C CB  . TRP A 1 109 ? 75.348  66.219  -26.179 1.00 6.89   ? 109 TRP A1 CB  1 
ATOM 567  C CG  . TRP A 1 109 ? 74.508  66.750  -25.102 1.00 8.21   ? 109 TRP A1 CG  1 
ATOM 568  C CD1 . TRP A 1 109 ? 74.188  68.046  -24.885 1.00 8.04   ? 109 TRP A1 CD1 1 
ATOM 569  C CD2 . TRP A 1 109 ? 73.880  66.001  -24.066 1.00 8.71   ? 109 TRP A1 CD2 1 
ATOM 570  N NE1 . TRP A 1 109 ? 73.397  68.158  -23.776 1.00 8.17   ? 109 TRP A1 NE1 1 
ATOM 571  C CE2 . TRP A 1 109 ? 73.195  66.910  -23.254 1.00 9.43   ? 109 TRP A1 CE2 1 
ATOM 572  C CE3 . TRP A 1 109 ? 73.833  64.645  -23.744 1.00 8.12   ? 109 TRP A1 CE3 1 
ATOM 573  C CZ2 . TRP A 1 109 ? 72.468  66.511  -22.149 1.00 9.17   ? 109 TRP A1 CZ2 1 
ATOM 574  C CZ3 . TRP A 1 109 ? 73.123  64.257  -22.646 1.00 8.34   ? 109 TRP A1 CZ3 1 
ATOM 575  C CH2 . TRP A 1 109 ? 72.442  65.179  -21.865 1.00 9.08   ? 109 TRP A1 CH2 1 
ATOM 576  N N   . SER A 1 110 ? 78.014  64.344  -26.492 1.00 7.32   ? 110 SER A1 N   1 
ATOM 577  C CA  . SER A 1 110 ? 78.741  63.433  -27.357 1.00 7.61   ? 110 SER A1 CA  1 
ATOM 578  C C   . SER A 1 110 ? 77.778  62.431  -27.964 1.00 6.78   ? 110 SER A1 C   1 
ATOM 579  O O   . SER A 1 110 ? 76.653  62.282  -27.500 1.00 6.73   ? 110 SER A1 O   1 
ATOM 580  C CB  . SER A 1 110 ? 79.839  62.715  -26.586 1.00 9.36   ? 110 SER A1 CB  1 
ATOM 581  O OG  . SER A 1 110 ? 80.840  63.634  -26.203 1.00 13.73  ? 110 SER A1 OG  1 
ATOM 582  N N   . LEU A 1 111 ? 78.208  61.766  -29.027 1.00 6.15   ? 111 LEU A1 N   1 
ATOM 583  C CA  . LEU A 1 111 ? 77.353  60.842  -29.757 1.00 6.43   ? 111 LEU A1 CA  1 
ATOM 584  C C   . LEU A 1 111 ? 78.013  59.474  -29.834 1.00 6.97   ? 111 LEU A1 C   1 
ATOM 585  O O   . LEU A 1 111 ? 79.155  59.360  -30.285 1.00 9.60   ? 111 LEU A1 O   1 
ATOM 586  C CB  . LEU A 1 111 ? 77.071  61.369  -31.159 1.00 4.56   ? 111 LEU A1 CB  1 
ATOM 587  C CG  . LEU A 1 111 ? 76.131  60.554  -32.036 1.00 3.03   ? 111 LEU A1 CG  1 
ATOM 588  C CD1 . LEU A 1 111 ? 74.802  60.372  -31.358 1.00 2.50   ? 111 LEU A1 CD1 1 
ATOM 589  C CD2 . LEU A 1 111 ? 75.953  61.237  -33.364 1.00 2.12   ? 111 LEU A1 CD2 1 
ATOM 590  N N   . VAL A 1 112 ? 77.295  58.440  -29.408 1.00 5.74   ? 112 VAL A1 N   1 
ATOM 591  C CA  . VAL A 1 112 ? 77.789  57.064  -29.469 1.00 5.16   ? 112 VAL A1 CA  1 
ATOM 592  C C   . VAL A 1 112 ? 77.140  56.424  -30.690 1.00 6.68   ? 112 VAL A1 C   1 
ATOM 593  O O   . VAL A 1 112 ? 76.084  55.801  -30.605 1.00 7.48   ? 112 VAL A1 O   1 
ATOM 594  C CB  . VAL A 1 112 ? 77.489  56.295  -28.186 1.00 3.33   ? 112 VAL A1 CB  1 
ATOM 595  C CG1 . VAL A 1 112 ? 78.228  54.990  -28.171 1.00 2.00   ? 112 VAL A1 CG1 1 
ATOM 596  C CG2 . VAL A 1 112 ? 77.886  57.107  -27.005 1.00 3.84   ? 112 VAL A1 CG2 1 
ATOM 597  N N   . ASP A 1 113 ? 77.791  56.557  -31.840 1.00 7.49   ? 113 ASP A1 N   1 
ATOM 598  C CA  . ASP A 1 113 ? 77.253  56.061  -33.098 1.00 8.38   ? 113 ASP A1 CA  1 
ATOM 599  C C   . ASP A 1 113 ? 77.836  54.693  -33.405 1.00 7.69   ? 113 ASP A1 C   1 
ATOM 600  O O   . ASP A 1 113 ? 79.031  54.467  -33.210 1.00 9.15   ? 113 ASP A1 O   1 
ATOM 601  C CB  . ASP A 1 113 ? 77.551  57.019  -34.248 1.00 11.17  ? 113 ASP A1 CB  1 
ATOM 602  C CG  . ASP A 1 113 ? 76.723  56.720  -35.477 1.00 13.77  ? 113 ASP A1 CG  1 
ATOM 603  O OD1 . ASP A 1 113 ? 77.309  56.461  -36.548 1.00 15.09  ? 113 ASP A1 OD1 1 
ATOM 604  O OD2 . ASP A 1 113 ? 75.481  56.740  -35.373 1.00 17.02  ? 113 ASP A1 OD2 1 
ATOM 605  N N   . ALA A 1 114 ? 76.997  53.793  -33.895 1.00 6.53   ? 114 ALA A1 N   1 
ATOM 606  C CA  . ALA A 1 114 ? 77.385  52.429  -34.207 1.00 4.97   ? 114 ALA A1 CA  1 
ATOM 607  C C   . ALA A 1 114 ? 76.889  52.038  -35.582 1.00 4.97   ? 114 ALA A1 C   1 
ATOM 608  O O   . ALA A 1 114 ? 76.599  50.873  -35.853 1.00 5.28   ? 114 ALA A1 O   1 
ATOM 609  C CB  . ALA A 1 114 ? 76.854  51.466  -33.158 1.00 3.23   ? 114 ALA A1 CB  1 
ATOM 610  N N   . ASN A 1 115 ? 76.779  53.014  -36.472 1.00 4.66   ? 115 ASN A1 N   1 
ATOM 611  C CA  . ASN A 1 115 ? 76.212  52.819  -37.796 1.00 4.83   ? 115 ASN A1 CA  1 
ATOM 612  C C   . ASN A 1 115 ? 77.356  52.685  -38.796 1.00 5.18   ? 115 ASN A1 C   1 
ATOM 613  O O   . ASN A 1 115 ? 77.613  53.576  -39.601 1.00 8.19   ? 115 ASN A1 O   1 
ATOM 614  C CB  . ASN A 1 115 ? 75.316  53.948  -38.129 1.00 4.50   ? 115 ASN A1 CB  1 
ATOM 615  C CG  . ASN A 1 115 ? 74.273  53.568  -39.108 1.00 4.50   ? 115 ASN A1 CG  1 
ATOM 616  O OD1 . ASN A 1 115 ? 74.151  52.405  -39.456 1.00 6.11   ? 115 ASN A1 OD1 1 
ATOM 617  N ND2 . ASN A 1 115 ? 73.505  54.537  -39.569 1.00 3.74   ? 115 ASN A1 ND2 1 
ATOM 618  N N   . ALA A 1 116 ? 78.042  51.551  -38.735 1.00 3.60   ? 116 ALA A1 N   1 
ATOM 619  C CA  . ALA A 1 116 ? 79.054  51.175  -39.709 1.00 4.07   ? 116 ALA A1 CA  1 
ATOM 620  C C   . ALA A 1 116 ? 79.145  49.665  -39.679 1.00 5.50   ? 116 ALA A1 C   1 
ATOM 621  O O   . ALA A 1 116 ? 78.804  49.045  -38.675 1.00 6.67   ? 116 ALA A1 O   1 
ATOM 622  C CB  . ALA A 1 116 ? 80.411  51.801  -39.408 1.00 2.19   ? 116 ALA A1 CB  1 
ATOM 623  N N   . TRP A 1 117 ? 79.590  49.075  -40.789 1.00 6.26   ? 117 TRP A1 N   1 
ATOM 624  C CA  . TRP A 1 117 ? 79.592  47.621  -40.888 1.00 6.18   ? 117 TRP A1 CA  1 
ATOM 625  C C   . TRP A 1 117 ? 80.639  46.987  -39.986 1.00 6.71   ? 117 TRP A1 C   1 
ATOM 626  O O   . TRP A 1 117 ? 80.402  45.914  -39.434 1.00 7.62   ? 117 TRP A1 O   1 
ATOM 627  C CB  . TRP A 1 117 ? 79.836  47.183  -42.325 1.00 4.92   ? 117 TRP A1 CB  1 
ATOM 628  C CG  . TRP A 1 117 ? 78.677  47.346  -43.215 1.00 5.15   ? 117 TRP A1 CG  1 
ATOM 629  C CD1 . TRP A 1 117 ? 78.538  48.257  -44.198 1.00 4.95   ? 117 TRP A1 CD1 1 
ATOM 630  C CD2 . TRP A 1 117 ? 77.488  46.556  -43.226 1.00 5.77   ? 117 TRP A1 CD2 1 
ATOM 631  N NE1 . TRP A 1 117 ? 77.332  48.102  -44.823 1.00 5.80   ? 117 TRP A1 NE1 1 
ATOM 632  C CE2 . TRP A 1 117 ? 76.669  47.056  -44.243 1.00 5.60   ? 117 TRP A1 CE2 1 
ATOM 633  C CE3 . TRP A 1 117 ? 77.038  45.472  -42.472 1.00 5.35   ? 117 TRP A1 CE3 1 
ATOM 634  C CZ2 . TRP A 1 117 ? 75.424  46.521  -44.522 1.00 4.74   ? 117 TRP A1 CZ2 1 
ATOM 635  C CZ3 . TRP A 1 117 ? 75.804  44.942  -42.753 1.00 5.26   ? 117 TRP A1 CZ3 1 
ATOM 636  C CH2 . TRP A 1 117 ? 75.010  45.468  -43.767 1.00 5.49   ? 117 TRP A1 CH2 1 
ATOM 637  N N   . GLY A 1 118 ? 81.784  47.630  -39.818 1.00 7.15   ? 118 GLY A1 N   1 
ATOM 638  C CA  . GLY A 1 118 ? 82.877  47.024  -39.094 1.00 7.41   ? 118 GLY A1 CA  1 
ATOM 639  C C   . GLY A 1 118 ? 82.784  47.093  -37.598 1.00 7.13   ? 118 GLY A1 C   1 
ATOM 640  O O   . GLY A 1 118 ? 83.600  46.472  -36.919 1.00 8.75   ? 118 GLY A1 O   1 
ATOM 641  N N   . VAL A 1 119 ? 81.810  47.835  -37.067 1.00 5.32   ? 119 VAL A1 N   1 
ATOM 642  C CA  . VAL A 1 119 ? 81.542  47.829  -35.633 1.00 6.05   ? 119 VAL A1 CA  1 
ATOM 643  C C   . VAL A 1 119 ? 81.045  46.456  -35.195 1.00 7.30   ? 119 VAL A1 C   1 
ATOM 644  O O   . VAL A 1 119 ? 81.237  46.053  -34.042 1.00 7.43   ? 119 VAL A1 O   1 
ATOM 645  C CB  . VAL A 1 119 ? 80.529  48.943  -35.297 1.00 6.25   ? 119 VAL A1 CB  1 
ATOM 646  C CG1 . VAL A 1 119 ? 80.416  49.174  -33.816 1.00 5.74   ? 119 VAL A1 CG1 1 
ATOM 647  C CG2 . VAL A 1 119 ? 80.911  50.223  -35.974 1.00 7.05   ? 119 VAL A1 CG2 1 
ATOM 648  N N   . TRP A 1 120 ? 80.453  45.693  -36.112 1.00 6.36   ? 120 TRP A1 N   1 
ATOM 649  C CA  . TRP A 1 120 ? 79.792  44.441  -35.801 1.00 5.13   ? 120 TRP A1 CA  1 
ATOM 650  C C   . TRP A 1 120 ? 80.503  43.209  -36.330 1.00 7.40   ? 120 TRP A1 C   1 
ATOM 651  O O   . TRP A 1 120 ? 80.575  42.210  -35.614 1.00 11.44  ? 120 TRP A1 O   1 
ATOM 652  C CB  . TRP A 1 120 ? 78.366  44.466  -36.353 1.00 3.92   ? 120 TRP A1 CB  1 
ATOM 653  C CG  . TRP A 1 120 ? 77.643  45.721  -36.012 1.00 4.35   ? 120 TRP A1 CG  1 
ATOM 654  C CD1 . TRP A 1 120 ? 77.618  46.873  -36.727 1.00 4.29   ? 120 TRP A1 CD1 1 
ATOM 655  C CD2 . TRP A 1 120 ? 76.844  45.955  -34.853 1.00 4.98   ? 120 TRP A1 CD2 1 
ATOM 656  N NE1 . TRP A 1 120 ? 76.858  47.812  -36.089 1.00 4.47   ? 120 TRP A1 NE1 1 
ATOM 657  C CE2 . TRP A 1 120 ? 76.369  47.269  -34.933 1.00 5.14   ? 120 TRP A1 CE2 1 
ATOM 658  C CE3 . TRP A 1 120 ? 76.480  45.178  -33.759 1.00 3.54   ? 120 TRP A1 CE3 1 
ATOM 659  C CZ2 . TRP A 1 120 ? 75.549  47.813  -33.972 1.00 4.47   ? 120 TRP A1 CZ2 1 
ATOM 660  C CZ3 . TRP A 1 120 ? 75.679  45.718  -32.812 1.00 3.01   ? 120 TRP A1 CZ3 1 
ATOM 661  C CH2 . TRP A 1 120 ? 75.222  47.022  -32.916 1.00 3.25   ? 120 TRP A1 CH2 1 
ATOM 662  N N   . PHE A 1 121 ? 81.038  43.249  -37.549 1.00 6.82   ? 121 PHE A1 N   1 
ATOM 663  C CA  . PHE A 1 121 ? 81.596  42.076  -38.211 1.00 5.87   ? 121 PHE A1 CA  1 
ATOM 664  C C   . PHE A 1 121 ? 83.105  42.205  -38.350 1.00 5.40   ? 121 PHE A1 C   1 
ATOM 665  O O   . PHE A 1 121 ? 83.596  43.211  -38.864 1.00 6.31   ? 121 PHE A1 O   1 
ATOM 666  C CB  . PHE A 1 121 ? 80.985  41.890  -39.599 1.00 6.94   ? 121 PHE A1 CB  1 
ATOM 667  C CG  . PHE A 1 121 ? 79.491  41.772  -39.607 1.00 7.30   ? 121 PHE A1 CG  1 
ATOM 668  C CD1 . PHE A 1 121 ? 78.865  40.671  -39.061 1.00 7.49   ? 121 PHE A1 CD1 1 
ATOM 669  C CD2 . PHE A 1 121 ? 78.716  42.757  -40.183 1.00 8.01   ? 121 PHE A1 CD2 1 
ATOM 670  C CE1 . PHE A 1 121 ? 77.499  40.569  -39.074 1.00 7.57   ? 121 PHE A1 CE1 1 
ATOM 671  C CE2 . PHE A 1 121 ? 77.348  42.656  -40.199 1.00 8.21   ? 121 PHE A1 CE2 1 
ATOM 672  C CZ  . PHE A 1 121 ? 76.742  41.560  -39.647 1.00 7.88   ? 121 PHE A1 CZ  1 
ATOM 673  N N   . ASN A 1 122 ? 83.839  41.182  -37.913 1.00 4.23   ? 122 ASN A1 N   1 
ATOM 674  C CA  . ASN A 1 122 ? 85.257  41.067  -38.210 1.00 2.74   ? 122 ASN A1 CA  1 
ATOM 675  C C   . ASN A 1 122 ? 85.440  40.479  -39.607 1.00 3.19   ? 122 ASN A1 C   1 
ATOM 676  O O   . ASN A 1 122 ? 84.487  39.934  -40.166 1.00 2.48   ? 122 ASN A1 O   1 
ATOM 677  C CB  . ASN A 1 122 ? 85.951  40.237  -37.123 1.00 3.10   ? 122 ASN A1 CB  1 
ATOM 678  C CG  . ASN A 1 122 ? 85.273  38.946  -36.850 1.00 3.57   ? 122 ASN A1 CG  1 
ATOM 679  O OD1 . ASN A 1 122 ? 84.263  38.649  -37.431 1.00 6.18   ? 122 ASN A1 OD1 1 
ATOM 680  N ND2 . ASN A 1 122 ? 85.832  38.160  -35.952 1.00 3.20   ? 122 ASN A1 ND2 1 
ATOM 681  N N   . PRO A 1 123 ? 86.619  40.644  -40.240 1.00 3.43   ? 123 PRO A1 N   1 
ATOM 682  C CA  . PRO A 1 123 ? 86.772  40.221  -41.644 1.00 4.57   ? 123 PRO A1 CA  1 
ATOM 683  C C   . PRO A 1 123 ? 86.569  38.749  -41.908 1.00 5.19   ? 123 PRO A1 C   1 
ATOM 684  O O   . PRO A 1 123 ? 86.221  38.390  -43.036 1.00 5.59   ? 123 PRO A1 O   1 
ATOM 685  C CB  . PRO A 1 123 ? 88.209  40.624  -41.968 1.00 3.56   ? 123 PRO A1 CB  1 
ATOM 686  C CG  . PRO A 1 123 ? 88.429  41.775  -41.160 1.00 5.18   ? 123 PRO A1 CG  1 
ATOM 687  C CD  . PRO A 1 123 ? 87.732  41.537  -39.871 1.00 3.59   ? 123 PRO A1 CD  1 
ATOM 688  N N   . GLY A 1 124 ? 86.753  37.891  -40.921 1.00 4.73   ? 124 GLY A1 N   1 
ATOM 689  C CA  . GLY A 1 124 ? 86.450  36.495  -41.097 1.00 6.03   ? 124 GLY A1 CA  1 
ATOM 690  C C   . GLY A 1 124 ? 84.978  36.194  -41.082 1.00 7.79   ? 124 GLY A1 C   1 
ATOM 691  O O   . GLY A 1 124 ? 84.576  35.070  -41.391 1.00 9.37   ? 124 GLY A1 O   1 
ATOM 692  N N   . ASP A 1 125 ? 84.157  37.176  -40.746 1.00 7.94   ? 125 ASP A1 N   1 
ATOM 693  C CA  . ASP A 1 125 ? 82.721  37.028  -40.744 1.00 9.44   ? 125 ASP A1 CA  1 
ATOM 694  C C   . ASP A 1 125 ? 82.027  37.896  -41.769 1.00 9.50   ? 125 ASP A1 C   1 
ATOM 695  O O   . ASP A 1 125 ? 80.796  37.897  -41.798 1.00 11.41  ? 125 ASP A1 O   1 
ATOM 696  C CB  . ASP A 1 125 ? 82.149  37.370  -39.373 1.00 12.33  ? 125 ASP A1 CB  1 
ATOM 697  C CG  . ASP A 1 125 ? 81.104  36.424  -38.942 1.00 16.65  ? 125 ASP A1 CG  1 
ATOM 698  O OD1 . ASP A 1 125 ? 80.369  35.938  -39.813 1.00 19.01  ? 125 ASP A1 OD1 1 
ATOM 699  O OD2 . ASP A 1 125 ? 81.037  36.139  -37.734 1.00 16.85  ? 125 ASP A1 OD2 1 
ATOM 700  N N   . TRP A 1 126 ? 82.755  38.705  -42.542 1.00 7.20   ? 126 TRP A1 N   1 
ATOM 701  C CA  . TRP A 1 126 ? 82.106  39.197  -43.738 1.00 5.83   ? 126 TRP A1 CA  1 
ATOM 702  C C   . TRP A 1 126 ? 81.894  37.983  -44.631 1.00 8.60   ? 126 TRP A1 C   1 
ATOM 703  O O   . TRP A 1 126 ? 80.784  37.451  -44.633 1.00 10.62  ? 126 TRP A1 O   1 
ATOM 704  C CB  . TRP A 1 126 ? 82.924  40.307  -44.392 1.00 5.60   ? 126 TRP A1 CB  1 
ATOM 705  C CG  . TRP A 1 126 ? 82.163  41.208  -45.321 1.00 5.60   ? 126 TRP A1 CG  1 
ATOM 706  C CD1 . TRP A 1 126 ? 82.497  41.498  -46.600 1.00 4.55   ? 126 TRP A1 CD1 1 
ATOM 707  C CD2 . TRP A 1 126 ? 80.957  41.948  -45.049 1.00 5.58   ? 126 TRP A1 CD2 1 
ATOM 708  N NE1 . TRP A 1 126 ? 81.583  42.350  -47.152 1.00 5.88   ? 126 TRP A1 NE1 1 
ATOM 709  C CE2 . TRP A 1 126 ? 80.626  42.642  -46.220 1.00 5.23   ? 126 TRP A1 CE2 1 
ATOM 710  C CE3 . TRP A 1 126 ? 80.125  42.086  -43.933 1.00 6.99   ? 126 TRP A1 CE3 1 
ATOM 711  C CZ2 . TRP A 1 126 ? 79.514  43.462  -46.309 1.00 5.29   ? 126 TRP A1 CZ2 1 
ATOM 712  C CZ3 . TRP A 1 126 ? 79.024  42.891  -44.030 1.00 6.47   ? 126 TRP A1 CZ3 1 
ATOM 713  C CH2 . TRP A 1 126 ? 78.726  43.570  -45.206 1.00 4.54   ? 126 TRP A1 CH2 1 
ATOM 714  N N   . GLN A 1 127 ? 82.881  37.508  -45.409 1.00 8.37   ? 127 GLN A1 N   1 
ATOM 715  C CA  . GLN A 1 127 ? 83.368  36.127  -45.618 1.00 7.12   ? 127 GLN A1 CA  1 
ATOM 716  C C   . GLN A 1 127 ? 82.384  34.945  -45.536 1.00 8.02   ? 127 GLN A1 C   1 
ATOM 717  O O   . GLN A 1 127 ? 82.583  33.915  -46.181 1.00 9.27   ? 127 GLN A1 O   1 
ATOM 718  C CB  . GLN A 1 127 ? 84.537  35.884  -44.653 1.00 6.44   ? 127 GLN A1 CB  1 
ATOM 719  C CG  . GLN A 1 127 ? 85.292  34.528  -44.729 1.00 5.93   ? 127 GLN A1 CG  1 
ATOM 720  C CD  . GLN A 1 127 ? 86.035  34.286  -46.028 1.00 5.89   ? 127 GLN A1 CD  1 
ATOM 721  O OE1 . GLN A 1 127 ? 85.448  33.947  -47.041 1.00 6.30   ? 127 GLN A1 OE1 1 
ATOM 722  N NE2 . GLN A 1 127 ? 87.346  34.439  -45.988 1.00 5.09   ? 127 GLN A1 NE2 1 
ATOM 723  N N   . LEU A 1 128 ? 81.260  35.123  -44.862 1.00 8.29   ? 128 LEU A1 N   1 
ATOM 724  C CA  . LEU A 1 128 ? 80.282  34.100  -44.548 1.00 7.29   ? 128 LEU A1 CA  1 
ATOM 725  C C   . LEU A 1 128 ? 78.881  34.631  -44.690 1.00 7.09   ? 128 LEU A1 C   1 
ATOM 726  O O   . LEU A 1 128 ? 77.934  33.846  -44.742 1.00 6.83   ? 128 LEU A1 O   1 
ATOM 727  C CB  . LEU A 1 128 ? 80.497  33.593  -43.117 1.00 7.12   ? 128 LEU A1 CB  1 
ATOM 728  C CG  . LEU A 1 128 ? 79.911  32.284  -42.594 1.00 6.72   ? 128 LEU A1 CG  1 
ATOM 729  C CD1 . LEU A 1 128 ? 80.174  31.144  -43.536 1.00 7.28   ? 128 LEU A1 CD1 1 
ATOM 730  C CD2 . LEU A 1 128 ? 80.514  31.989  -41.256 1.00 7.28   ? 128 LEU A1 CD2 1 
ATOM 731  N N   . ILE A 1 129 ? 78.722  35.947  -44.722 1.00 7.09   ? 129 ILE A1 N   1 
ATOM 732  C CA  . ILE A 1 129 ? 77.551  36.592  -45.268 1.00 7.65   ? 129 ILE A1 CA  1 
ATOM 733  C C   . ILE A 1 129 ? 77.705  36.809  -46.759 1.00 8.24   ? 129 ILE A1 C   1 
ATOM 734  O O   . ILE A 1 129 ? 76.758  36.634  -47.524 1.00 8.51   ? 129 ILE A1 O   1 
ATOM 735  C CB  . ILE A 1 129 ? 77.330  37.931  -44.540 1.00 7.19   ? 129 ILE A1 CB  1 
ATOM 736  C CG1 . ILE A 1 129 ? 77.399  37.721  -43.037 1.00 6.65   ? 129 ILE A1 CG1 1 
ATOM 737  C CG2 . ILE A 1 129 ? 76.019  38.545  -44.921 1.00 6.09   ? 129 ILE A1 CG2 1 
ATOM 738  C CD1 . ILE A 1 129 ? 77.635  38.981  -42.297 1.00 6.95   ? 129 ILE A1 CD1 1 
ATOM 739  N N   . VAL A 1 130 ? 78.925  37.118  -47.180 1.00 8.04   ? 130 VAL A1 N   1 
ATOM 740  C CA  . VAL A 1 130 ? 79.118  37.761  -48.462 1.00 5.84   ? 130 VAL A1 CA  1 
ATOM 741  C C   . VAL A 1 130 ? 79.212  36.745  -49.592 1.00 7.08   ? 130 VAL A1 C   1 
ATOM 742  O O   . VAL A 1 130 ? 78.915  37.070  -50.746 1.00 10.88  ? 130 VAL A1 O   1 
ATOM 743  C CB  . VAL A 1 130 ? 80.347  38.678  -48.366 1.00 2.95   ? 130 VAL A1 CB  1 
ATOM 744  C CG1 . VAL A 1 130 ? 81.640  37.922  -48.517 1.00 2.50   ? 130 VAL A1 CG1 1 
ATOM 745  C CG2 . VAL A 1 130 ? 80.262  39.714  -49.365 1.00 2.19   ? 130 VAL A1 CG2 1 
ATOM 746  N N   . ASN A 1 131 ? 79.584  35.497  -49.298 1.00 6.29   ? 131 ASN A1 N   1 
ATOM 747  C CA  . ASN A 1 131 ? 79.634  34.487  -50.341 1.00 5.55   ? 131 ASN A1 CA  1 
ATOM 748  C C   . ASN A 1 131 ? 78.883  33.225  -49.958 1.00 6.53   ? 131 ASN A1 C   1 
ATOM 749  O O   . ASN A 1 131 ? 79.037  32.199  -50.625 1.00 7.14   ? 131 ASN A1 O   1 
ATOM 750  C CB  . ASN A 1 131 ? 81.081  34.161  -50.734 1.00 4.65   ? 131 ASN A1 CB  1 
ATOM 751  C CG  . ASN A 1 131 ? 81.968  33.845  -49.564 1.00 5.27   ? 131 ASN A1 CG  1 
ATOM 752  O OD1 . ASN A 1 131 ? 81.646  33.018  -48.725 1.00 4.88   ? 131 ASN A1 OD1 1 
ATOM 753  N ND2 . ASN A 1 131 ? 83.118  34.483  -49.522 1.00 5.23   ? 131 ASN A1 ND2 1 
ATOM 754  N N   . THR A 1 132 ? 78.092  33.270  -48.899 1.00 6.36   ? 132 THR A1 N   1 
ATOM 755  C CA  . THR A 1 132 ? 77.183  32.196  -48.555 1.00 6.59   ? 132 THR A1 CA  1 
ATOM 756  C C   . THR A 1 132 ? 75.728  32.618  -48.660 1.00 7.60   ? 132 THR A1 C   1 
ATOM 757  O O   . THR A 1 132 ? 74.910  31.830  -49.142 1.00 9.53   ? 132 THR A1 O   1 
ATOM 758  C CB  . THR A 1 132 ? 77.483  31.691  -47.134 1.00 6.50   ? 132 THR A1 CB  1 
ATOM 759  O OG1 . THR A 1 132 ? 78.851  31.278  -47.056 1.00 8.53   ? 132 THR A1 OG1 1 
ATOM 760  C CG2 . THR A 1 132 ? 76.646  30.504  -46.777 1.00 8.52   ? 132 THR A1 CG2 1 
ATOM 761  N N   . MET A 1 133 ? 75.395  33.856  -48.307 1.00 7.55   ? 133 MET A1 N   1 
ATOM 762  C CA  . MET A 1 133 ? 74.039  34.371  -48.391 1.00 7.33   ? 133 MET A1 CA  1 
ATOM 763  C C   . MET A 1 133 ? 73.816  35.121  -49.699 1.00 7.94   ? 133 MET A1 C   1 
ATOM 764  O O   . MET A 1 133 ? 74.759  35.519  -50.380 1.00 9.42   ? 133 MET A1 O   1 
ATOM 765  C CB  . MET A 1 133 ? 73.733  35.291  -47.213 1.00 9.21   ? 133 MET A1 CB  1 
ATOM 766  C CG  . MET A 1 133 ? 74.376  34.850  -45.933 1.00 10.98  ? 133 MET A1 CG  1 
ATOM 767  S SD  . MET A 1 133 ? 73.524  33.490  -45.152 1.00 11.69  ? 133 MET A1 SD  1 
ATOM 768  C CE  . MET A 1 133 ? 74.774  32.959  -43.992 1.00 11.20  ? 133 MET A1 CE  1 
ATOM 769  N N   . SER A 1 134 ? 72.544  35.305  -50.045 1.00 7.61   ? 134 SER A1 N   1 
ATOM 770  C CA  . SER A 1 134 ? 72.163  35.950  -51.297 1.00 7.78   ? 134 SER A1 CA  1 
ATOM 771  C C   . SER A 1 134 ? 71.410  37.253  -51.106 1.00 9.75   ? 134 SER A1 C   1 
ATOM 772  O O   . SER A 1 134 ? 71.666  38.210  -51.833 1.00 12.77  ? 134 SER A1 O   1 
ATOM 773  C CB  . SER A 1 134 ? 71.312  35.011  -52.149 1.00 7.56   ? 134 SER A1 CB  1 
ATOM 774  O OG  . SER A 1 134 ? 69.940  35.200  -51.877 1.00 9.97   ? 134 SER A1 OG  1 
ATOM 775  N N   . GLU A 1 135 ? 70.466  37.316  -50.175 1.00 10.30  ? 135 GLU A1 N   1 
ATOM 776  C CA  . GLU A 1 135 ? 69.875  38.579  -49.767 1.00 10.95  ? 135 GLU A1 CA  1 
ATOM 777  C C   . GLU A 1 135 ? 69.975  38.694  -48.259 1.00 9.89   ? 135 GLU A1 C   1 
ATOM 778  O O   . GLU A 1 135 ? 70.317  37.737  -47.565 1.00 11.19  ? 135 GLU A1 O   1 
ATOM 779  C CB  . GLU A 1 135 ? 68.421  38.722  -50.221 1.00 13.03  ? 135 GLU A1 CB  1 
ATOM 780  C CG  . GLU A 1 135 ? 67.448  37.830  -49.506 1.00 19.28  ? 135 GLU A1 CG  1 
ATOM 781  C CD  . GLU A 1 135 ? 66.283  37.450  -50.391 1.00 22.98  ? 135 GLU A1 CD  1 
ATOM 782  O OE1 . GLU A 1 135 ? 66.299  37.827  -51.580 1.00 24.94  ? 135 GLU A1 OE1 1 
ATOM 783  O OE2 . GLU A 1 135 ? 65.355  36.771  -49.905 1.00 26.13  ? 135 GLU A1 OE2 1 
ATOM 784  N N   . LEU A 1 136 ? 69.674  39.883  -47.750 1.00 7.95   ? 136 LEU A1 N   1 
ATOM 785  C CA  . LEU A 1 136 ? 69.948  40.205  -46.355 1.00 7.47   ? 136 LEU A1 CA  1 
ATOM 786  C C   . LEU A 1 136 ? 69.063  41.368  -45.956 1.00 6.81   ? 136 LEU A1 C   1 
ATOM 787  O O   . LEU A 1 136 ? 69.031  42.376  -46.661 1.00 7.47   ? 136 LEU A1 O   1 
ATOM 788  C CB  . LEU A 1 136 ? 71.421  40.558  -46.184 1.00 7.29   ? 136 LEU A1 CB  1 
ATOM 789  C CG  . LEU A 1 136 ? 71.985  41.186  -44.919 1.00 6.71   ? 136 LEU A1 CG  1 
ATOM 790  C CD1 . LEU A 1 136 ? 72.214  40.137  -43.870 1.00 5.29   ? 136 LEU A1 CD1 1 
ATOM 791  C CD2 . LEU A 1 136 ? 73.288  41.875  -45.239 1.00 5.19   ? 136 LEU A1 CD2 1 
ATOM 792  N N   . HIS A 1 137 ? 68.338  41.241  -44.848 1.00 6.87   ? 137 HIS A1 N   1 
ATOM 793  C CA  . HIS A 1 137 ? 67.624  42.393  -44.324 1.00 7.08   ? 137 HIS A1 CA  1 
ATOM 794  C C   . HIS A 1 137 ? 67.742  42.477  -42.813 1.00 6.70   ? 137 HIS A1 C   1 
ATOM 795  O O   . HIS A 1 137 ? 68.146  41.535  -42.134 1.00 8.60   ? 137 HIS A1 O   1 
ATOM 796  C CB  . HIS A 1 137 ? 66.156  42.440  -44.772 1.00 8.32   ? 137 HIS A1 CB  1 
ATOM 797  C CG  . HIS A 1 137 ? 65.483  41.111  -44.867 1.00 10.83  ? 137 HIS A1 CG  1 
ATOM 798  N ND1 . HIS A 1 137 ? 64.727  40.581  -43.846 1.00 12.25  ? 137 HIS A1 ND1 1 
ATOM 799  C CD2 . HIS A 1 137 ? 65.411  40.226  -45.888 1.00 11.28  ? 137 HIS A1 CD2 1 
ATOM 800  C CE1 . HIS A 1 137 ? 64.235  39.416  -44.229 1.00 12.21  ? 137 HIS A1 CE1 1 
ATOM 801  N NE2 . HIS A 1 137 ? 64.635  39.179  -45.465 1.00 11.76  ? 137 HIS A1 NE2 1 
ATOM 802  N N   . LEU A 1 138 ? 67.383  43.652  -42.316 1.00 4.98   ? 138 LEU A1 N   1 
ATOM 803  C CA  . LEU A 1 138 ? 67.756  44.151  -41.004 1.00 4.40   ? 138 LEU A1 CA  1 
ATOM 804  C C   . LEU A 1 138 ? 66.544  44.079  -40.090 1.00 5.79   ? 138 LEU A1 C   1 
ATOM 805  O O   . LEU A 1 138 ? 65.476  44.587  -40.436 1.00 8.03   ? 138 LEU A1 O   1 
ATOM 806  C CB  . LEU A 1 138 ? 68.261  45.583  -41.156 1.00 2.91   ? 138 LEU A1 CB  1 
ATOM 807  C CG  . LEU A 1 138 ? 68.846  46.462  -40.072 1.00 2.00   ? 138 LEU A1 CG  1 
ATOM 808  C CD1 . LEU A 1 138 ? 69.895  45.740  -39.318 1.00 2.25   ? 138 LEU A1 CD1 1 
ATOM 809  C CD2 . LEU A 1 138 ? 69.440  47.679  -40.721 1.00 2.02   ? 138 LEU A1 CD2 1 
ATOM 810  N N   . VAL A 1 139 ? 66.708  43.447  -38.931 1.00 6.35   ? 139 VAL A1 N   1 
ATOM 811  C CA  . VAL A 1 139 ? 65.586  43.030  -38.097 1.00 7.05   ? 139 VAL A1 CA  1 
ATOM 812  C C   . VAL A 1 139 ? 65.428  43.923  -36.869 1.00 7.96   ? 139 VAL A1 C   1 
ATOM 813  O O   . VAL A 1 139 ? 64.381  44.536  -36.674 1.00 8.65   ? 139 VAL A1 O   1 
ATOM 814  C CB  . VAL A 1 139 ? 65.714  41.543  -37.702 1.00 6.85   ? 139 VAL A1 CB  1 
ATOM 815  C CG1 . VAL A 1 139 ? 64.670  41.169  -36.694 1.00 6.33   ? 139 VAL A1 CG1 1 
ATOM 816  C CG2 . VAL A 1 139 ? 65.578  40.678  -38.923 1.00 5.26   ? 139 VAL A1 CG2 1 
ATOM 817  N N   . SER A 1 140 ? 66.452  44.001  -36.023 1.00 8.80   ? 140 SER A1 N   1 
ATOM 818  C CA  . SER A 1 140 ? 66.331  44.734  -34.772 1.00 11.66  ? 140 SER A1 CA  1 
ATOM 819  C C   . SER A 1 140 ? 67.669  45.370  -34.422 1.00 13.44  ? 140 SER A1 C   1 
ATOM 820  O O   . SER A 1 140 ? 68.661  45.191  -35.126 1.00 14.78  ? 140 SER A1 O   1 
ATOM 821  C CB  . SER A 1 140 ? 65.845  43.829  -33.644 1.00 12.30  ? 140 SER A1 CB  1 
ATOM 822  O OG  . SER A 1 140 ? 66.848  42.921  -33.251 1.00 14.23  ? 140 SER A1 OG  1 
ATOM 823  N N   . PHE A 1 141 ? 67.684  46.122  -33.317 1.00 13.30  ? 141 PHE A1 N   1 
ATOM 824  C CA  . PHE A 1 141 ? 68.867  46.836  -32.848 1.00 11.10  ? 141 PHE A1 CA  1 
ATOM 825  C C   . PHE A 1 141 ? 68.674  47.245  -31.396 1.00 11.84  ? 141 PHE A1 C   1 
ATOM 826  O O   . PHE A 1 141 ? 67.702  47.927  -31.073 1.00 10.42  ? 141 PHE A1 O   1 
ATOM 827  C CB  . PHE A 1 141 ? 69.127  48.080  -33.686 1.00 8.05   ? 141 PHE A1 CB  1 
ATOM 828  C CG  . PHE A 1 141 ? 70.247  48.927  -33.178 1.00 6.86   ? 141 PHE A1 CG  1 
ATOM 829  C CD1 . PHE A 1 141 ? 71.501  48.388  -32.964 1.00 7.91   ? 141 PHE A1 CD1 1 
ATOM 830  C CD2 . PHE A 1 141 ? 70.052  50.268  -32.925 1.00 4.82   ? 141 PHE A1 CD2 1 
ATOM 831  C CE1 . PHE A 1 141 ? 72.527  49.161  -32.506 1.00 6.55   ? 141 PHE A1 CE1 1 
ATOM 832  C CE2 . PHE A 1 141 ? 71.084  51.043  -32.465 1.00 3.99   ? 141 PHE A1 CE2 1 
ATOM 833  C CZ  . PHE A 1 141 ? 72.322  50.486  -32.259 1.00 4.15   ? 141 PHE A1 CZ  1 
ATOM 834  N N   . GLU A 1 142 ? 69.613  46.863  -30.534 1.00 12.58  ? 142 GLU A1 N   1 
ATOM 835  C CA  . GLU A 1 142 ? 69.589  47.227  -29.126 1.00 13.73  ? 142 GLU A1 CA  1 
ATOM 836  C C   . GLU A 1 142 ? 70.838  48.014  -28.773 1.00 13.86  ? 142 GLU A1 C   1 
ATOM 837  O O   . GLU A 1 142 ? 71.800  48.072  -29.537 1.00 14.78  ? 142 GLU A1 O   1 
ATOM 838  C CB  . GLU A 1 142 ? 69.508  45.995  -28.228 1.00 15.63  ? 142 GLU A1 CB  1 
ATOM 839  C CG  . GLU A 1 142 ? 68.460  45.005  -28.631 1.00 22.96  ? 142 GLU A1 CG  1 
ATOM 840  C CD  . GLU A 1 142 ? 68.186  44.002  -27.542 1.00 27.84  ? 142 GLU A1 CD  1 
ATOM 841  O OE1 . GLU A 1 142 ? 68.385  44.351  -26.361 1.00 29.72  ? 142 GLU A1 OE1 1 
ATOM 842  O OE2 . GLU A 1 142 ? 67.767  42.871  -27.862 1.00 32.00  ? 142 GLU A1 OE2 1 
ATOM 843  N N   . GLN A 1 143 ? 70.825  48.608  -27.587 1.00 13.24  ? 143 GLN A1 N   1 
ATOM 844  C CA  . GLN A 1 143 ? 71.933  49.417  -27.108 1.00 11.90  ? 143 GLN A1 CA  1 
ATOM 845  C C   . GLN A 1 143 ? 71.890  49.438  -25.593 1.00 12.40  ? 143 GLN A1 C   1 
ATOM 846  O O   . GLN A 1 143 ? 70.822  49.533  -24.992 1.00 11.82  ? 143 GLN A1 O   1 
ATOM 847  C CB  . GLN A 1 143 ? 71.858  50.842  -27.638 1.00 10.33  ? 143 GLN A1 CB  1 
ATOM 848  C CG  . GLN A 1 143 ? 72.818  51.175  -28.729 1.00 10.57  ? 143 GLN A1 CG  1 
ATOM 849  C CD  . GLN A 1 143 ? 72.647  52.595  -29.191 1.00 11.50  ? 143 GLN A1 CD  1 
ATOM 850  O OE1 . GLN A 1 143 ? 71.533  53.105  -29.240 1.00 11.69  ? 143 GLN A1 OE1 1 
ATOM 851  N NE2 . GLN A 1 143 ? 73.747  53.246  -29.532 1.00 14.08  ? 143 GLN A1 NE2 1 
ATOM 852  N N   . GLU A 1 144 ? 73.060  49.320  -24.973 1.00 12.57  ? 144 GLU A1 N   1 
ATOM 853  C CA  . GLU A 1 144 ? 73.157  49.355  -23.520 1.00 13.08  ? 144 GLU A1 CA  1 
ATOM 854  C C   . GLU A 1 144 ? 74.381  50.155  -23.125 1.00 12.23  ? 144 GLU A1 C   1 
ATOM 855  O O   . GLU A 1 144 ? 75.281  50.376  -23.932 1.00 11.97  ? 144 GLU A1 O   1 
ATOM 856  C CB  . GLU A 1 144 ? 73.264  47.964  -22.890 1.00 15.31  ? 144 GLU A1 CB  1 
ATOM 857  C CG  . GLU A 1 144 ? 72.139  47.014  -23.223 1.00 21.29  ? 144 GLU A1 CG  1 
ATOM 858  C CD  . GLU A 1 144 ? 72.603  45.587  -23.314 1.00 26.32  ? 144 GLU A1 CD  1 
ATOM 859  O OE1 . GLU A 1 144 ? 73.190  45.112  -22.322 1.00 29.39  ? 144 GLU A1 OE1 1 
ATOM 860  O OE2 . GLU A 1 144 ? 72.404  44.955  -24.377 1.00 27.83  ? 144 GLU A1 OE2 1 
ATOM 861  N N   . ILE A 1 145 ? 74.404  50.582  -21.870 1.00 10.01  ? 145 ILE A1 N   1 
ATOM 862  C CA  . ILE A 1 145 ? 75.546  51.256  -21.265 1.00 7.15   ? 145 ILE A1 CA  1 
ATOM 863  C C   . ILE A 1 145 ? 75.683  50.697  -19.860 1.00 6.97   ? 145 ILE A1 C   1 
ATOM 864  O O   . ILE A 1 145 ? 74.738  50.765  -19.072 1.00 6.77   ? 145 ILE A1 O   1 
ATOM 865  C CB  . ILE A 1 145 ? 75.374  52.783  -21.231 1.00 5.50   ? 145 ILE A1 CB  1 
ATOM 866  C CG1 . ILE A 1 145 ? 75.657  53.383  -22.600 1.00 5.59   ? 145 ILE A1 CG1 1 
ATOM 867  C CG2 . ILE A 1 145 ? 76.300  53.417  -20.218 1.00 3.30   ? 145 ILE A1 CG2 1 
ATOM 868  C CD1 . ILE A 1 145 ? 75.463  54.857  -22.650 1.00 7.57   ? 145 ILE A1 CD1 1 
ATOM 869  N N   . PHE A 1 146 ? 76.836  50.125  -19.546 1.00 6.50   ? 146 PHE A1 N   1 
ATOM 870  C CA  . PHE A 1 146 ? 77.012  49.446  -18.277 1.00 6.93   ? 146 PHE A1 CA  1 
ATOM 871  C C   . PHE A 1 146 ? 78.428  49.673  -17.780 1.00 8.19   ? 146 PHE A1 C   1 
ATOM 872  O O   . PHE A 1 146 ? 79.291  50.140  -18.522 1.00 9.30   ? 146 PHE A1 O   1 
ATOM 873  C CB  . PHE A 1 146 ? 76.691  47.951  -18.390 1.00 4.81   ? 146 PHE A1 CB  1 
ATOM 874  C CG  . PHE A 1 146 ? 77.547  47.202  -19.371 1.00 3.67   ? 146 PHE A1 CG  1 
ATOM 875  C CD1 . PHE A 1 146 ? 77.214  47.147  -20.703 1.00 3.88   ? 146 PHE A1 CD1 1 
ATOM 876  C CD2 . PHE A 1 146 ? 78.654  46.510  -18.944 1.00 3.00   ? 146 PHE A1 CD2 1 
ATOM 877  C CE1 . PHE A 1 146 ? 77.991  46.458  -21.582 1.00 2.54   ? 146 PHE A1 CE1 1 
ATOM 878  C CE2 . PHE A 1 146 ? 79.429  45.816  -19.821 1.00 2.88   ? 146 PHE A1 CE2 1 
ATOM 879  C CZ  . PHE A 1 146 ? 79.100  45.792  -21.144 1.00 3.32   ? 146 PHE A1 CZ  1 
ATOM 880  N N   . ASN A 1 147 ? 78.638  49.334  -16.506 1.00 9.23   ? 147 ASN A1 N   1 
ATOM 881  C CA  . ASN A 1 147 ? 79.898  49.506  -15.774 1.00 8.36   ? 147 ASN A1 CA  1 
ATOM 882  C C   . ASN A 1 147 ? 80.457  50.919  -15.923 1.00 9.27   ? 147 ASN A1 C   1 
ATOM 883  O O   . ASN A 1 147 ? 81.601  51.128  -16.316 1.00 12.25  ? 147 ASN A1 O   1 
ATOM 884  C CB  . ASN A 1 147 ? 80.934  48.463  -16.190 1.00 5.36   ? 147 ASN A1 CB  1 
ATOM 885  C CG  . ASN A 1 147 ? 80.656  47.102  -15.613 1.00 3.80   ? 147 ASN A1 CG  1 
ATOM 886  O OD1 . ASN A 1 147 ? 80.364  46.160  -16.331 1.00 4.92   ? 147 ASN A1 OD1 1 
ATOM 887  N ND2 . ASN A 1 147 ? 80.769  46.987  -14.306 1.00 2.37   ? 147 ASN A1 ND2 1 
ATOM 888  N N   . VAL A 1 148 ? 79.612  51.889  -15.607 1.00 7.55   ? 148 VAL A1 N   1 
ATOM 889  C CA  . VAL A 1 148 ? 79.976  53.293  -15.720 1.00 3.87   ? 148 VAL A1 CA  1 
ATOM 890  C C   . VAL A 1 148 ? 80.974  53.626  -14.623 1.00 4.56   ? 148 VAL A1 C   1 
ATOM 891  O O   . VAL A 1 148 ? 80.780  53.262  -13.460 1.00 5.78   ? 148 VAL A1 O   1 
ATOM 892  C CB  . VAL A 1 148 ? 78.727  54.179  -15.628 1.00 2.91   ? 148 VAL A1 CB  1 
ATOM 893  C CG1 . VAL A 1 148 ? 79.086  55.631  -15.816 1.00 3.32   ? 148 VAL A1 CG1 1 
ATOM 894  C CG2 . VAL A 1 148 ? 77.706  53.747  -16.650 1.00 3.12   ? 148 VAL A1 CG2 1 
ATOM 895  N N   . VAL A 1 149 ? 82.057  54.293  -14.995 1.00 3.07   ? 149 VAL A1 N   1 
ATOM 896  C CA  . VAL A 1 149 ? 83.128  54.658  -14.079 1.00 3.25   ? 149 VAL A1 CA  1 
ATOM 897  C C   . VAL A 1 149 ? 83.466  56.106  -14.359 1.00 6.32   ? 149 VAL A1 C   1 
ATOM 898  O O   . VAL A 1 149 ? 83.777  56.450  -15.501 1.00 7.74   ? 149 VAL A1 O   1 
ATOM 899  C CB  . VAL A 1 149 ? 84.366  53.766  -14.268 1.00 2.00   ? 149 VAL A1 CB  1 
ATOM 900  C CG1 . VAL A 1 149 ? 85.602  54.416  -13.704 1.00 2.00   ? 149 VAL A1 CG1 1 
ATOM 901  C CG2 . VAL A 1 149 ? 84.153  52.425  -13.610 1.00 2.97   ? 149 VAL A1 CG2 1 
ATOM 902  N N   . LEU A 1 150 ? 83.384  56.959  -13.343 1.00 9.12   ? 150 LEU A1 N   1 
ATOM 903  C CA  . LEU A 1 150 ? 83.809  58.344  -13.476 1.00 8.83   ? 150 LEU A1 CA  1 
ATOM 904  C C   . LEU A 1 150 ? 84.970  58.619  -12.539 1.00 9.82   ? 150 LEU A1 C   1 
ATOM 905  O O   . LEU A 1 150 ? 84.934  58.251  -11.365 1.00 12.48  ? 150 LEU A1 O   1 
ATOM 906  C CB  . LEU A 1 150 ? 82.693  59.341  -13.178 1.00 7.17   ? 150 LEU A1 CB  1 
ATOM 907  C CG  . LEU A 1 150 ? 81.617  59.513  -14.243 1.00 6.12   ? 150 LEU A1 CG  1 
ATOM 908  C CD1 . LEU A 1 150 ? 80.479  58.546  -14.003 1.00 4.79   ? 150 LEU A1 CD1 1 
ATOM 909  C CD2 . LEU A 1 150 ? 81.147  60.939  -14.335 1.00 4.88   ? 150 LEU A1 CD2 1 
ATOM 910  N N   . LYS A 1 151 ? 85.992  59.276  -13.068 1.00 9.54   ? 151 LYS A1 N   1 
ATOM 911  C CA  . LYS A 1 151 ? 87.196  59.575  -12.321 1.00 7.74   ? 151 LYS A1 CA  1 
ATOM 912  C C   . LYS A 1 151 ? 87.540  61.040  -12.512 1.00 8.32   ? 151 LYS A1 C   1 
ATOM 913  O O   . LYS A 1 151 ? 87.195  61.642  -13.527 1.00 6.22   ? 151 LYS A1 O   1 
ATOM 914  C CB  . LYS A 1 151 ? 88.362  58.704  -12.779 1.00 6.94   ? 151 LYS A1 CB  1 
ATOM 915  C CG  . LYS A 1 151 ? 88.241  57.253  -12.404 1.00 8.19   ? 151 LYS A1 CG  1 
ATOM 916  C CD  . LYS A 1 151 ? 89.261  56.425  -13.137 1.00 11.74  ? 151 LYS A1 CD  1 
ATOM 917  C CE  . LYS A 1 151 ? 89.769  55.295  -12.279 1.00 13.89  ? 151 LYS A1 CE  1 
ATOM 918  N NZ  . LYS A 1 151 ? 90.657  55.771  -11.186 1.00 16.91  ? 151 LYS A1 NZ  1 
ATOM 919  N N   . THR A 1 152 ? 88.208  61.614  -11.522 1.00 10.10  ? 152 THR A1 N   1 
ATOM 920  C CA  . THR A 1 152 ? 88.707  62.974  -11.607 1.00 13.33  ? 152 THR A1 CA  1 
ATOM 921  C C   . THR A 1 152 ? 90.219  62.988  -11.488 1.00 15.41  ? 152 THR A1 C   1 
ATOM 922  O O   . THR A 1 152 ? 90.806  62.244  -10.701 1.00 17.03  ? 152 THR A1 O   1 
ATOM 923  C CB  . THR A 1 152 ? 88.118  63.869  -10.523 1.00 12.08  ? 152 THR A1 CB  1 
ATOM 924  O OG1 . THR A 1 152 ? 88.457  63.349  -9.233  1.00 12.55  ? 152 THR A1 OG1 1 
ATOM 925  C CG2 . THR A 1 152 ? 86.632  63.966  -10.668 1.00 12.16  ? 152 THR A1 CG2 1 
ATOM 926  N N   . VAL A 1 153 ? 90.842  63.848  -12.277 1.00 18.12  ? 153 VAL A1 N   1 
ATOM 927  C CA  . VAL A 1 153 ? 92.285  64.007  -12.281 1.00 20.44  ? 153 VAL A1 CA  1 
ATOM 928  C C   . VAL A 1 153 ? 92.625  65.287  -11.528 1.00 24.37  ? 153 VAL A1 C   1 
ATOM 929  O O   . VAL A 1 153 ? 91.935  66.306  -11.664 1.00 24.69  ? 153 VAL A1 O   1 
ATOM 930  C CB  . VAL A 1 153 ? 92.839  63.987  -13.720 1.00 18.51  ? 153 VAL A1 CB  1 
ATOM 931  C CG1 . VAL A 1 153 ? 92.149  64.989  -14.591 1.00 18.72  ? 153 VAL A1 CG1 1 
ATOM 932  C CG2 . VAL A 1 153 ? 94.322  64.240  -13.743 1.00 17.67  ? 153 VAL A1 CG2 1 
ATOM 933  N N   . SER A 1 154 ? 93.630  65.210  -10.660 1.00 31.28  ? 154 SER A1 N   1 
ATOM 934  C CA  . SER A 1 154 ? 94.058  66.339  -9.840  1.00 37.15  ? 154 SER A1 CA  1 
ATOM 935  C C   . SER A 1 154 ? 95.567  66.240  -9.665  1.00 41.40  ? 154 SER A1 C   1 
ATOM 936  O O   . SER A 1 154 ? 96.059  65.300  -9.035  1.00 38.78  ? 154 SER A1 O   1 
ATOM 937  C CB  . SER A 1 154 ? 93.344  66.332  -8.497  1.00 37.49  ? 154 SER A1 CB  1 
ATOM 938  O OG  . SER A 1 154 ? 93.294  65.023  -7.966  1.00 38.95  ? 154 SER A1 OG  1 
ATOM 939  N N   . GLU A 1 155 ? 96.299  67.201  -10.219 1.00 50.94  ? 155 GLU A1 N   1 
ATOM 940  C CA  . GLU A 1 155 ? 97.750  67.204  -10.082 1.00 61.09  ? 155 GLU A1 CA  1 
ATOM 941  C C   . GLU A 1 155 ? 98.156  67.600  -8.666  1.00 65.43  ? 155 GLU A1 C   1 
ATOM 942  O O   . GLU A 1 155 ? 97.624  68.559  -8.099  1.00 66.17  ? 155 GLU A1 O   1 
ATOM 943  C CB  . GLU A 1 155 ? 98.385  68.150  -11.105 1.00 64.13  ? 155 GLU A1 CB  1 
ATOM 944  C CG  . GLU A 1 155 ? 97.748  69.524  -11.223 1.00 69.90  ? 155 GLU A1 CG  1 
ATOM 945  C CD  . GLU A 1 155 ? 96.677  69.579  -12.291 1.00 74.17  ? 155 GLU A1 CD  1 
ATOM 946  O OE1 . GLU A 1 155 ? 96.839  70.349  -13.261 1.00 76.54  ? 155 GLU A1 OE1 1 
ATOM 947  O OE2 . GLU A 1 155 ? 95.671  68.854  -12.158 1.00 76.46  ? 155 GLU A1 OE2 1 
ATOM 948  N N   . SER A 1 156 ? 99.103  66.856  -8.091  1.00 70.70  ? 156 SER A1 N   1 
ATOM 949  C CA  . SER A 1 156 ? 99.619  67.154  -6.759  1.00 75.65  ? 156 SER A1 CA  1 
ATOM 950  C C   . SER A 1 156 ? 100.696 68.232  -6.819  1.00 78.74  ? 156 SER A1 C   1 
ATOM 951  O O   . SER A 1 156 ? 100.527 69.307  -6.234  1.00 78.40  ? 156 SER A1 O   1 
ATOM 952  C CB  . SER A 1 156 ? 100.166 65.877  -6.105  1.00 75.92  ? 156 SER A1 CB  1 
ATOM 953  O OG  . SER A 1 156 ? 101.384 65.472  -6.706  1.00 76.26  ? 156 SER A1 OG  1 
ATOM 954  N N   . ALA A 1 157 ? 101.800 67.943  -7.519  1.00 82.37  ? 157 ALA A1 N   1 
ATOM 955  C CA  . ALA A 1 157 ? 102.760 68.920  -8.045  1.00 86.07  ? 157 ALA A1 CA  1 
ATOM 956  C C   . ALA A 1 157 ? 103.420 69.758  -6.943  1.00 88.32  ? 157 ALA A1 C   1 
ATOM 957  O O   . ALA A 1 157 ? 103.204 70.965  -6.826  1.00 89.41  ? 157 ALA A1 O   1 
ATOM 958  C CB  . ALA A 1 157 ? 102.090 69.824  -9.089  1.00 86.18  ? 157 ALA A1 CB  1 
ATOM 959  N N   . THR A 1 158 ? 104.232 69.087  -6.124  1.00 89.28  ? 158 THR A1 N   1 
ATOM 960  C CA  . THR A 1 158 ? 105.230 69.829  -5.359  1.00 90.18  ? 158 THR A1 CA  1 
ATOM 961  C C   . THR A 1 158 ? 106.334 70.342  -6.284  1.00 91.15  ? 158 THR A1 C   1 
ATOM 962  O O   . THR A 1 158 ? 106.569 71.554  -6.366  1.00 90.72  ? 158 THR A1 O   1 
ATOM 963  C CB  . THR A 1 158 ? 105.763 68.983  -4.186  1.00 90.24  ? 158 THR A1 CB  1 
ATOM 964  O OG1 . THR A 1 158 ? 106.915 69.611  -3.603  1.00 90.33  ? 158 THR A1 OG1 1 
ATOM 965  C CG2 . THR A 1 158 ? 106.018 67.502  -4.539  1.00 90.12  ? 158 THR A1 CG2 1 
ATOM 966  N N   . GLN A 1 159 ? 107.032 69.431  -6.979  1.00 92.59  ? 159 GLN A1 N   1 
ATOM 967  C CA  . GLN A 1 159 ? 107.522 69.637  -8.341  1.00 94.21  ? 159 GLN A1 CA  1 
ATOM 968  C C   . GLN A 1 159 ? 107.635 68.302  -9.106  1.00 92.85  ? 159 GLN A1 C   1 
ATOM 969  O O   . GLN A 1 159 ? 108.736 67.931  -9.537  1.00 92.68  ? 159 GLN A1 O   1 
ATOM 970  C CB  . GLN A 1 159 ? 108.860 70.404  -8.306  1.00 96.58  ? 159 GLN A1 CB  1 
ATOM 971  C CG  . GLN A 1 159 ? 109.403 70.979  -9.642  1.00 100.28 ? 159 GLN A1 CG  1 
ATOM 972  C CD  . GLN A 1 159 ? 108.325 71.598  -10.510 1.00 102.73 ? 159 GLN A1 CD  1 
ATOM 973  O OE1 . GLN A 1 159 ? 107.654 72.545  -10.107 1.00 104.01 ? 159 GLN A1 OE1 1 
ATOM 974  N NE2 . GLN A 1 159 ? 108.160 71.065  -11.714 1.00 103.61 ? 159 GLN A1 NE2 1 
ATOM 975  N N   . PRO A 1 160 ? 106.577 67.494  -9.234  1.00 91.53  ? 160 PRO A1 N   1 
ATOM 976  C CA  . PRO A 1 160 ? 106.356 66.814  -10.509 1.00 89.72  ? 160 PRO A1 CA  1 
ATOM 977  C C   . PRO A 1 160 ? 105.295 67.539  -11.313 1.00 87.12  ? 160 PRO A1 C   1 
ATOM 978  O O   . PRO A 1 160 ? 104.643 68.462  -10.803 1.00 86.94  ? 160 PRO A1 O   1 
ATOM 979  C CB  . PRO A 1 160 ? 105.888 65.407  -10.094 1.00 90.56  ? 160 PRO A1 CB  1 
ATOM 980  C CG  . PRO A 1 160 ? 106.049 65.344  -8.613  1.00 91.25  ? 160 PRO A1 CG  1 
ATOM 981  C CD  . PRO A 1 160 ? 105.867 66.744  -8.180  1.00 91.11  ? 160 PRO A1 CD  1 
ATOM 982  N N   . PRO A 1 161 ? 105.101 67.170  -12.572 1.00 84.81  ? 161 PRO A1 N   1 
ATOM 983  C CA  . PRO A 1 161 ? 103.845 67.515  -13.249 1.00 81.60  ? 161 PRO A1 CA  1 
ATOM 984  C C   . PRO A 1 161 ? 102.797 66.419  -13.093 1.00 77.64  ? 161 PRO A1 C   1 
ATOM 985  O O   . PRO A 1 161 ? 101.826 66.383  -13.856 1.00 78.78  ? 161 PRO A1 O   1 
ATOM 986  C CB  . PRO A 1 161 ? 104.266 67.686  -14.717 1.00 83.26  ? 161 PRO A1 CB  1 
ATOM 987  C CG  . PRO A 1 161 ? 105.779 67.554  -14.735 1.00 84.57  ? 161 PRO A1 CG  1 
ATOM 988  C CD  . PRO A 1 161 ? 106.129 66.747  -13.532 1.00 84.69  ? 161 PRO A1 CD  1 
ATOM 989  N N   . THR A 1 162 ? 102.994 65.521  -12.122 1.00 70.95  ? 162 THR A1 N   1 
ATOM 990  C CA  . THR A 1 162 ? 102.269 64.258  -12.058 1.00 65.31  ? 162 THR A1 CA  1 
ATOM 991  C C   . THR A 1 162 ? 100.796 64.470  -11.712 1.00 59.12  ? 162 THR A1 C   1 
ATOM 992  O O   . THR A 1 162 ? 100.378 65.528  -11.240 1.00 58.34  ? 162 THR A1 O   1 
ATOM 993  C CB  . THR A 1 162 ? 102.913 63.316  -11.041 1.00 67.07  ? 162 THR A1 CB  1 
ATOM 994  O OG1 . THR A 1 162 ? 102.431 61.984  -11.252 1.00 68.54  ? 162 THR A1 OG1 1 
ATOM 995  C CG2 . THR A 1 162 ? 102.584 63.739  -9.614  1.00 67.10  ? 162 THR A1 CG2 1 
ATOM 996  N N   . LYS A 1 163 ? 100.002 63.432  -11.977 1.00 50.71  ? 163 LYS A1 N   1 
ATOM 997  C CA  . LYS A 1 163 ? 98.557  63.482  -11.842 1.00 42.80  ? 163 LYS A1 CA  1 
ATOM 998  C C   . LYS A 1 163 ? 98.082  62.360  -10.934 1.00 36.51  ? 163 LYS A1 C   1 
ATOM 999  O O   . LYS A 1 163 ? 98.713  61.307  -10.829 1.00 34.62  ? 163 LYS A1 O   1 
ATOM 1000 C CB  . LYS A 1 163 ? 97.862  63.362  -13.201 1.00 42.67  ? 163 LYS A1 CB  1 
ATOM 1001 C CG  . LYS A 1 163 ? 98.367  64.314  -14.258 1.00 42.54  ? 163 LYS A1 CG  1 
ATOM 1002 C CD  . LYS A 1 163 ? 97.800  65.701  -14.042 1.00 43.99  ? 163 LYS A1 CD  1 
ATOM 1003 C CE  . LYS A 1 163 ? 97.567  66.419  -15.356 1.00 45.59  ? 163 LYS A1 CE  1 
ATOM 1004 N NZ  . LYS A 1 163 ? 96.479  67.427  -15.244 1.00 47.07  ? 163 LYS A1 NZ  1 
ATOM 1005 N N   . VAL A 1 164 ? 96.954  62.604  -10.271 1.00 30.68  ? 164 VAL A1 N   1 
ATOM 1006 C CA  . VAL A 1 164 ? 96.311  61.627  -9.401  1.00 24.42  ? 164 VAL A1 CA  1 
ATOM 1007 C C   . VAL A 1 164 ? 94.905  61.402  -9.929  1.00 20.36  ? 164 VAL A1 C   1 
ATOM 1008 O O   . VAL A 1 164 ? 94.124  62.353  -10.037 1.00 17.10  ? 164 VAL A1 O   1 
ATOM 1009 C CB  . VAL A 1 164 ? 96.259  62.087  -7.934  1.00 23.53  ? 164 VAL A1 CB  1 
ATOM 1010 C CG1 . VAL A 1 164 ? 95.919  60.919  -7.033  1.00 24.01  ? 164 VAL A1 CG1 1 
ATOM 1011 C CG2 . VAL A 1 164 ? 97.567  62.726  -7.503  1.00 23.86  ? 164 VAL A1 CG2 1 
ATOM 1012 N N   . TYR A 1 165 ? 94.579  60.155  -10.248 1.00 17.88  ? 165 TYR A1 N   1 
ATOM 1013 C CA  . TYR A 1 165 ? 93.268  59.788  -10.769 1.00 17.70  ? 165 TYR A1 CA  1 
ATOM 1014 C C   . TYR A 1 165 ? 92.513  59.027  -9.688  1.00 18.07  ? 165 TYR A1 C   1 
ATOM 1015 O O   . TYR A 1 165 ? 92.812  57.860  -9.427  1.00 19.49  ? 165 TYR A1 O   1 
ATOM 1016 C CB  . TYR A 1 165 ? 93.402  58.929  -12.022 1.00 16.46  ? 165 TYR A1 CB  1 
ATOM 1017 C CG  . TYR A 1 165 ? 94.436  59.400  -13.008 1.00 15.08  ? 165 TYR A1 CG  1 
ATOM 1018 C CD1 . TYR A 1 165 ? 94.138  60.385  -13.933 1.00 16.20  ? 165 TYR A1 CD1 1 
ATOM 1019 C CD2 . TYR A 1 165 ? 95.702  58.837  -13.032 1.00 13.29  ? 165 TYR A1 CD2 1 
ATOM 1020 C CE1 . TYR A 1 165 ? 95.072  60.807  -14.843 1.00 16.29  ? 165 TYR A1 CE1 1 
ATOM 1021 C CE2 . TYR A 1 165 ? 96.645  59.254  -13.935 1.00 13.57  ? 165 TYR A1 CE2 1 
ATOM 1022 C CZ  . TYR A 1 165 ? 96.323  60.240  -14.838 1.00 16.55  ? 165 TYR A1 CZ  1 
ATOM 1023 O OH  . TYR A 1 165 ? 97.265  60.662  -15.746 1.00 20.68  ? 165 TYR A1 OH  1 
ATOM 1024 N N   . ASN A 1 166 ? 91.533  59.673  -9.067  1.00 18.35  ? 166 ASN A1 N   1 
ATOM 1025 C CA  . ASN A 1 166 ? 90.734  59.031  -8.036  1.00 19.10  ? 166 ASN A1 CA  1 
ATOM 1026 C C   . ASN A 1 166 ? 89.279  58.953  -8.468  1.00 18.34  ? 166 ASN A1 C   1 
ATOM 1027 O O   . ASN A 1 166 ? 88.779  59.828  -9.176  1.00 19.32  ? 166 ASN A1 O   1 
ATOM 1028 C CB  . ASN A 1 166 ? 90.850  59.768  -6.699  1.00 22.76  ? 166 ASN A1 CB  1 
ATOM 1029 C CG  . ASN A 1 166 ? 90.854  61.269  -6.859  1.00 26.42  ? 166 ASN A1 CG  1 
ATOM 1030 O OD1 . ASN A 1 166 ? 91.651  61.820  -7.612  1.00 29.24  ? 166 ASN A1 OD1 1 
ATOM 1031 N ND2 . ASN A 1 166 ? 89.966  61.942  -6.141  1.00 26.99  ? 166 ASN A1 ND2 1 
ATOM 1032 N N   . ASN A 1 167 ? 88.607  57.891  -8.031  1.00 16.73  ? 167 ASN A1 N   1 
ATOM 1033 C CA  . ASN A 1 167 ? 87.222  57.646  -8.395  1.00 14.91  ? 167 ASN A1 CA  1 
ATOM 1034 C C   . ASN A 1 167 ? 86.298  58.674  -7.754  1.00 13.56  ? 167 ASN A1 C   1 
ATOM 1035 O O   . ASN A 1 167 ? 86.520  59.137  -6.633  1.00 14.41  ? 167 ASN A1 O   1 
ATOM 1036 C CB  . ASN A 1 167 ? 86.789  56.251  -7.949  1.00 15.80  ? 167 ASN A1 CB  1 
ATOM 1037 C CG  . ASN A 1 167 ? 87.507  55.146  -8.690  1.00 19.50  ? 167 ASN A1 CG  1 
ATOM 1038 O OD1 . ASN A 1 167 ? 88.307  54.415  -8.108  1.00 24.20  ? 167 ASN A1 OD1 1 
ATOM 1039 N ND2 . ASN A 1 167 ? 87.206  55.001  -9.973  1.00 19.70  ? 167 ASN A1 ND2 1 
ATOM 1040 N N   . ASP A 1 168 ? 85.240  59.027  -8.480  1.00 10.83  ? 168 ASP A1 N   1 
ATOM 1041 C CA  . ASP A 1 168 ? 84.128  59.799  -7.937  1.00 8.09   ? 168 ASP A1 CA  1 
ATOM 1042 C C   . ASP A 1 168 ? 82.895  58.912  -7.928  1.00 6.72   ? 168 ASP A1 C   1 
ATOM 1043 O O   . ASP A 1 168 ? 82.297  58.661  -8.977  1.00 8.01   ? 168 ASP A1 O   1 
ATOM 1044 C CB  . ASP A 1 168 ? 83.867  61.072  -8.730  1.00 8.99   ? 168 ASP A1 CB  1 
ATOM 1045 C CG  . ASP A 1 168 ? 84.710  62.223  -8.261  1.00 10.67  ? 168 ASP A1 CG  1 
ATOM 1046 O OD1 . ASP A 1 168 ? 84.291  63.381  -8.468  1.00 10.52  ? 168 ASP A1 OD1 1 
ATOM 1047 O OD2 . ASP A 1 168 ? 85.796  61.976  -7.693  1.00 11.12  ? 168 ASP A1 OD2 1 
ATOM 1048 N N   . LEU A 1 169 ? 82.516  58.447  -6.746  1.00 4.88   ? 169 LEU A1 N   1 
ATOM 1049 C CA  . LEU A 1 169 ? 81.401  57.527  -6.617  1.00 4.48   ? 169 LEU A1 CA  1 
ATOM 1050 C C   . LEU A 1 169 ? 80.054  58.224  -6.683  1.00 6.13   ? 169 LEU A1 C   1 
ATOM 1051 O O   . LEU A 1 169 ? 79.025  57.544  -6.734  1.00 8.45   ? 169 LEU A1 O   1 
ATOM 1052 C CB  . LEU A 1 169 ? 81.523  56.754  -5.307  1.00 2.25   ? 169 LEU A1 CB  1 
ATOM 1053 C CG  . LEU A 1 169 ? 82.903  56.158  -5.046  1.00 2.00   ? 169 LEU A1 CG  1 
ATOM 1054 C CD1 . LEU A 1 169 ? 82.927  55.458  -3.709  1.00 2.00   ? 169 LEU A1 CD1 1 
ATOM 1055 C CD2 . LEU A 1 169 ? 83.301  55.200  -6.153  1.00 2.00   ? 169 LEU A1 CD2 1 
ATOM 1056 N N   . THR A 1 170 ? 80.033  59.555  -6.679  1.00 7.01   ? 170 THR A1 N   1 
ATOM 1057 C CA  . THR A 1 170 ? 78.797  60.305  -6.755  1.00 6.79   ? 170 THR A1 CA  1 
ATOM 1058 C C   . THR A 1 170 ? 78.672  61.161  -8.004  1.00 6.33   ? 170 THR A1 C   1 
ATOM 1059 O O   . THR A 1 170 ? 77.640  61.817  -8.176  1.00 6.47   ? 170 THR A1 O   1 
ATOM 1060 C CB  . THR A 1 170 ? 78.645  61.204  -5.524  1.00 6.93   ? 170 THR A1 CB  1 
ATOM 1061 O OG1 . THR A 1 170 ? 79.737  62.126  -5.478  1.00 10.49  ? 170 THR A1 OG1 1 
ATOM 1062 C CG2 . THR A 1 170 ? 78.640  60.369  -4.262  1.00 5.83   ? 170 THR A1 CG2 1 
ATOM 1063 N N   . ALA A 1 171 ? 79.679  61.182  -8.869  1.00 5.67   ? 171 ALA A1 N   1 
ATOM 1064 C CA  . ALA A 1 171 ? 79.562  61.893  -10.128 1.00 6.28   ? 171 ALA A1 CA  1 
ATOM 1065 C C   . ALA A 1 171 ? 78.677  61.111  -11.085 1.00 6.66   ? 171 ALA A1 C   1 
ATOM 1066 O O   . ALA A 1 171 ? 78.679  59.881  -11.105 1.00 9.16   ? 171 ALA A1 O   1 
ATOM 1067 C CB  . ALA A 1 171 ? 80.933  62.123  -10.752 1.00 5.51   ? 171 ALA A1 CB  1 
ATOM 1068 N N   . SER A 1 172 ? 77.918  61.845  -11.891 1.00 4.70   ? 172 SER A1 N   1 
ATOM 1069 C CA  . SER A 1 172 ? 76.900  61.258  -12.744 1.00 5.11   ? 172 SER A1 CA  1 
ATOM 1070 C C   . SER A 1 172 ? 77.320  61.347  -14.202 1.00 6.46   ? 172 SER A1 C   1 
ATOM 1071 O O   . SER A 1 172 ? 78.091  62.218  -14.599 1.00 9.16   ? 172 SER A1 O   1 
ATOM 1072 C CB  . SER A 1 172 ? 75.550  61.955  -12.563 1.00 5.22   ? 172 SER A1 CB  1 
ATOM 1073 O OG  . SER A 1 172 ? 75.172  62.006  -11.202 1.00 9.15   ? 172 SER A1 OG  1 
ATOM 1074 N N   . LEU A 1 173 ? 76.788  60.427  -14.996 1.00 6.01   ? 173 LEU A1 N   1 
ATOM 1075 C CA  . LEU A 1 173 ? 76.903  60.456  -16.446 1.00 4.96   ? 173 LEU A1 CA  1 
ATOM 1076 C C   . LEU A 1 173 ? 75.516  60.697  -17.011 1.00 6.55   ? 173 LEU A1 C   1 
ATOM 1077 O O   . LEU A 1 173 ? 74.594  59.925  -16.739 1.00 6.92   ? 173 LEU A1 O   1 
ATOM 1078 C CB  . LEU A 1 173 ? 77.478  59.149  -16.984 1.00 3.62   ? 173 LEU A1 CB  1 
ATOM 1079 C CG  . LEU A 1 173 ? 77.723  59.104  -18.486 1.00 3.00   ? 173 LEU A1 CG  1 
ATOM 1080 C CD1 . LEU A 1 173 ? 79.086  59.650  -18.773 1.00 2.46   ? 173 LEU A1 CD1 1 
ATOM 1081 C CD2 . LEU A 1 173 ? 77.602  57.697  -19.006 1.00 2.00   ? 173 LEU A1 CD2 1 
ATOM 1082 N N   . MET A 1 174 ? 75.362  61.766  -17.774 1.00 5.87   ? 174 MET A1 N   1 
ATOM 1083 C CA  . MET A 1 174 ? 74.081  62.105  -18.366 1.00 5.96   ? 174 MET A1 CA  1 
ATOM 1084 C C   . MET A 1 174 ? 73.923  61.365  -19.685 1.00 6.44   ? 174 MET A1 C   1 
ATOM 1085 O O   . MET A 1 174 ? 74.752  61.510  -20.581 1.00 8.80   ? 174 MET A1 O   1 
ATOM 1086 C CB  . MET A 1 174 ? 73.982  63.610  -18.585 1.00 5.69   ? 174 MET A1 CB  1 
ATOM 1087 C CG  . MET A 1 174 ? 74.332  64.435  -17.376 1.00 6.55   ? 174 MET A1 CG  1 
ATOM 1088 S SD  . MET A 1 174 ? 74.201  66.194  -17.697 1.00 7.95   ? 174 MET A1 SD  1 
ATOM 1089 C CE  . MET A 1 174 ? 72.428  66.396  -17.670 1.00 9.90   ? 174 MET A1 CE  1 
ATOM 1090 N N   . VAL A 1 175 ? 72.872  60.557  -19.797 1.00 5.60   ? 175 VAL A1 N   1 
ATOM 1091 C CA  . VAL A 1 175 ? 72.589  59.794  -21.007 1.00 4.35   ? 175 VAL A1 CA  1 
ATOM 1092 C C   . VAL A 1 175 ? 71.205  60.179  -21.502 1.00 5.63   ? 175 VAL A1 C   1 
ATOM 1093 O O   . VAL A 1 175 ? 70.243  60.167  -20.731 1.00 7.01   ? 175 VAL A1 O   1 
ATOM 1094 C CB  . VAL A 1 175 ? 72.657  58.277  -20.774 1.00 3.26   ? 175 VAL A1 CB  1 
ATOM 1095 C CG1 . VAL A 1 175 ? 72.651  57.558  -22.098 1.00 4.36   ? 175 VAL A1 CG1 1 
ATOM 1096 C CG2 . VAL A 1 175 ? 73.884  57.900  -19.995 1.00 4.08   ? 175 VAL A1 CG2 1 
ATOM 1097 N N   . ALA A 1 176 ? 71.101  60.503  -22.784 1.00 4.77   ? 176 ALA A1 N   1 
ATOM 1098 C CA  . ALA A 1 176 ? 69.836  60.857  -23.409 1.00 4.37   ? 176 ALA A1 CA  1 
ATOM 1099 C C   . ALA A 1 176 ? 69.668  60.065  -24.693 1.00 5.91   ? 176 ALA A1 C   1 
ATOM 1100 O O   . ALA A 1 176 ? 70.489  60.179  -25.604 1.00 8.17   ? 176 ALA A1 O   1 
ATOM 1101 C CB  . ALA A 1 176 ? 69.777  62.352  -23.708 1.00 3.42   ? 176 ALA A1 CB  1 
ATOM 1102 N N   . LEU A 1 177 ? 68.606  59.278  -24.775 1.00 6.12   ? 177 LEU A1 N   1 
ATOM 1103 C CA  . LEU A 1 177 ? 68.274  58.535  -25.984 1.00 4.52   ? 177 LEU A1 CA  1 
ATOM 1104 C C   . LEU A 1 177 ? 67.121  59.245  -26.678 1.00 5.34   ? 177 LEU A1 C   1 
ATOM 1105 O O   . LEU A 1 177 ? 66.026  59.352  -26.119 1.00 5.63   ? 177 LEU A1 O   1 
ATOM 1106 C CB  . LEU A 1 177 ? 67.905  57.091  -25.669 1.00 3.69   ? 177 LEU A1 CB  1 
ATOM 1107 C CG  . LEU A 1 177 ? 67.289  56.343  -26.849 1.00 2.00   ? 177 LEU A1 CG  1 
ATOM 1108 C CD1 . LEU A 1 177 ? 68.340  55.786  -27.778 1.00 2.70   ? 177 LEU A1 CD1 1 
ATOM 1109 C CD2 . LEU A 1 177 ? 66.370  55.254  -26.365 1.00 2.00   ? 177 LEU A1 CD2 1 
ATOM 1110 N N   . ASP A 1 178 ? 67.363  59.717  -27.898 1.00 6.06   ? 178 ASP A1 N   1 
ATOM 1111 C CA  . ASP A 1 178 ? 66.353  60.447  -28.660 1.00 6.29   ? 178 ASP A1 CA  1 
ATOM 1112 C C   . ASP A 1 178 ? 65.435  59.458  -29.377 1.00 7.22   ? 178 ASP A1 C   1 
ATOM 1113 O O   . ASP A 1 178 ? 65.496  59.250  -30.589 1.00 8.22   ? 178 ASP A1 O   1 
ATOM 1114 C CB  . ASP A 1 178 ? 67.023  61.400  -29.637 1.00 6.46   ? 178 ASP A1 CB  1 
ATOM 1115 C CG  . ASP A 1 178 ? 66.028  62.235  -30.405 1.00 7.01   ? 178 ASP A1 CG  1 
ATOM 1116 O OD1 . ASP A 1 178 ? 64.967  62.572  -29.840 1.00 4.82   ? 178 ASP A1 OD1 1 
ATOM 1117 O OD2 . ASP A 1 178 ? 66.299  62.528  -31.584 1.00 8.47   ? 178 ASP A1 OD2 1 
ATOM 1118 N N   . SER A 1 179 ? 64.545  58.846  -28.598 1.00 9.22   ? 179 SER A1 N   1 
ATOM 1119 C CA  . SER A 1 179 ? 63.698  57.794  -29.143 1.00 12.38  ? 179 SER A1 CA  1 
ATOM 1120 C C   . SER A 1 179 ? 62.588  58.329  -30.037 1.00 12.39  ? 179 SER A1 C   1 
ATOM 1121 O O   . SER A 1 179 ? 62.021  57.562  -30.818 1.00 12.70  ? 179 SER A1 O   1 
ATOM 1122 C CB  . SER A 1 179 ? 63.104  56.968  -28.006 1.00 14.50  ? 179 SER A1 CB  1 
ATOM 1123 O OG  . SER A 1 179 ? 62.671  57.806  -26.951 1.00 18.29  ? 179 SER A1 OG  1 
ATOM 1124 N N   . ASN A 1 180 ? 62.268  59.619  -29.952 1.00 14.15  ? 180 ASN A1 N   1 
ATOM 1125 C CA  . ASN A 1 180 ? 61.209  60.210  -30.758 1.00 15.40  ? 180 ASN A1 CA  1 
ATOM 1126 C C   . ASN A 1 180 ? 61.719  60.842  -32.041 1.00 14.56  ? 180 ASN A1 C   1 
ATOM 1127 O O   . ASN A 1 180 ? 60.906  61.366  -32.809 1.00 17.15  ? 180 ASN A1 O   1 
ATOM 1128 C CB  . ASN A 1 180 ? 60.449  61.261  -29.951 1.00 20.42  ? 180 ASN A1 CB  1 
ATOM 1129 C CG  . ASN A 1 180 ? 59.831  60.693  -28.700 1.00 25.79  ? 180 ASN A1 CG  1 
ATOM 1130 O OD1 . ASN A 1 180 ? 60.084  59.547  -28.336 1.00 29.19  ? 180 ASN A1 OD1 1 
ATOM 1131 N ND2 . ASN A 1 180 ? 59.006  61.489  -28.034 1.00 28.46  ? 180 ASN A1 ND2 1 
ATOM 1132 N N   . ASN A 1 181 ? 63.034  60.797  -32.277 1.00 12.62  ? 181 ASN A1 N   1 
ATOM 1133 C CA  . ASN A 1 181 ? 63.712  61.394  -33.431 1.00 11.40  ? 181 ASN A1 CA  1 
ATOM 1134 C C   . ASN A 1 181 ? 63.405  62.887  -33.554 1.00 9.55   ? 181 ASN A1 C   1 
ATOM 1135 O O   . ASN A 1 181 ? 63.001  63.386  -34.602 1.00 8.52   ? 181 ASN A1 O   1 
ATOM 1136 C CB  . ASN A 1 181 ? 63.372  60.644  -34.723 1.00 13.27  ? 181 ASN A1 CB  1 
ATOM 1137 C CG  . ASN A 1 181 ? 63.966  59.252  -34.758 1.00 17.04  ? 181 ASN A1 CG  1 
ATOM 1138 O OD1 . ASN A 1 181 ? 63.244  58.257  -34.755 1.00 18.10  ? 181 ASN A1 OD1 1 
ATOM 1139 N ND2 . ASN A 1 181 ? 65.290  59.176  -34.795 1.00 17.74  ? 181 ASN A1 ND2 1 
ATOM 1140 N N   . THR A 1 182 ? 63.612  63.595  -32.449 1.00 7.25   ? 182 THR A1 N   1 
ATOM 1141 C CA  . THR A 1 182 ? 63.404  65.034  -32.412 1.00 6.44   ? 182 THR A1 CA  1 
ATOM 1142 C C   . THR A 1 182 ? 64.652  65.799  -32.839 1.00 6.02   ? 182 THR A1 C   1 
ATOM 1143 O O   . THR A 1 182 ? 64.556  66.913  -33.355 1.00 8.25   ? 182 THR A1 O   1 
ATOM 1144 C CB  . THR A 1 182 ? 62.972  65.458  -31.009 1.00 7.21   ? 182 THR A1 CB  1 
ATOM 1145 O OG1 . THR A 1 182 ? 63.790  64.794  -30.040 1.00 8.47   ? 182 THR A1 OG1 1 
ATOM 1146 C CG2 . THR A 1 182 ? 61.529  65.084  -30.770 1.00 8.43   ? 182 THR A1 CG2 1 
ATOM 1147 N N   . MET A 1 183 ? 65.820  65.213  -32.627 1.00 3.30   ? 183 MET A1 N   1 
ATOM 1148 C CA  . MET A 1 183 ? 67.071  65.854  -32.972 1.00 2.80   ? 183 MET A1 CA  1 
ATOM 1149 C C   . MET A 1 183 ? 67.315  65.794  -34.476 1.00 2.52   ? 183 MET A1 C   1 
ATOM 1150 O O   . MET A 1 183 ? 66.673  65.016  -35.182 1.00 3.24   ? 183 MET A1 O   1 
ATOM 1151 C CB  . MET A 1 183 ? 68.208  65.184  -32.207 1.00 3.70   ? 183 MET A1 CB  1 
ATOM 1152 C CG  . MET A 1 183 ? 68.214  65.495  -30.730 1.00 5.78   ? 183 MET A1 CG  1 
ATOM 1153 S SD  . MET A 1 183 ? 68.384  67.260  -30.426 1.00 8.62   ? 183 MET A1 SD  1 
ATOM 1154 C CE  . MET A 1 183 ? 66.771  67.676  -29.803 1.00 10.33  ? 183 MET A1 CE  1 
ATOM 1155 N N   . PRO A 1 184 ? 68.208  66.639  -34.998 1.00 2.94   ? 184 PRO A1 N   1 
ATOM 1156 C CA  . PRO A 1 184 ? 68.648  66.457  -36.384 1.00 2.07   ? 184 PRO A1 CA  1 
ATOM 1157 C C   . PRO A 1 184 ? 69.408  65.152  -36.538 1.00 2.59   ? 184 PRO A1 C   1 
ATOM 1158 O O   . PRO A 1 184 ? 70.272  64.819  -35.729 1.00 3.27   ? 184 PRO A1 O   1 
ATOM 1159 C CB  . PRO A 1 184 ? 69.552  67.668  -36.628 1.00 3.37   ? 184 PRO A1 CB  1 
ATOM 1160 C CG  . PRO A 1 184 ? 69.124  68.655  -35.656 1.00 2.14   ? 184 PRO A1 CG  1 
ATOM 1161 C CD  . PRO A 1 184 ? 68.690  67.919  -34.453 1.00 2.99   ? 184 PRO A1 CD  1 
ATOM 1162 N N   . PHE A 1 185 ? 69.064  64.397  -37.573 1.00 3.77   ? 185 PHE A1 N   1 
ATOM 1163 C CA  . PHE A 1 185 ? 69.703  63.106  -37.781 1.00 4.88   ? 185 PHE A1 CA  1 
ATOM 1164 C C   . PHE A 1 185 ? 71.046  63.323  -38.446 1.00 5.43   ? 185 PHE A1 C   1 
ATOM 1165 O O   . PHE A 1 185 ? 71.117  63.708  -39.615 1.00 8.01   ? 185 PHE A1 O   1 
ATOM 1166 C CB  . PHE A 1 185 ? 68.831  62.187  -38.622 1.00 5.36   ? 185 PHE A1 CB  1 
ATOM 1167 C CG  . PHE A 1 185 ? 69.425  60.831  -38.825 1.00 6.47   ? 185 PHE A1 CG  1 
ATOM 1168 C CD1 . PHE A 1 185 ? 69.533  59.952  -37.771 1.00 6.08   ? 185 PHE A1 CD1 1 
ATOM 1169 C CD2 . PHE A 1 185 ? 69.873  60.435  -40.069 1.00 6.95   ? 185 PHE A1 CD2 1 
ATOM 1170 C CE1 . PHE A 1 185 ? 70.081  58.705  -37.951 1.00 5.01   ? 185 PHE A1 CE1 1 
ATOM 1171 C CE2 . PHE A 1 185 ? 70.423  59.186  -40.256 1.00 5.77   ? 185 PHE A1 CE2 1 
ATOM 1172 C CZ  . PHE A 1 185 ? 70.528  58.322  -39.196 1.00 4.08   ? 185 PHE A1 CZ  1 
ATOM 1173 N N   . THR A 1 186 ? 72.112  63.080  -37.699 1.00 4.25   ? 186 THR A1 N   1 
ATOM 1174 C CA  . THR A 1 186 ? 73.469  63.262  -38.189 1.00 3.65   ? 186 THR A1 CA  1 
ATOM 1175 C C   . THR A 1 186 ? 74.159  61.908  -38.230 1.00 5.16   ? 186 THR A1 C   1 
ATOM 1176 O O   . THR A 1 186 ? 74.736  61.478  -37.222 1.00 3.89   ? 186 THR A1 O   1 
ATOM 1177 C CB  . THR A 1 186 ? 74.233  64.227  -37.281 1.00 2.31   ? 186 THR A1 CB  1 
ATOM 1178 O OG1 . THR A 1 186 ? 74.361  63.644  -35.982 1.00 3.47   ? 186 THR A1 OG1 1 
ATOM 1179 C CG2 . THR A 1 186 ? 73.490  65.543  -37.158 1.00 2.23   ? 186 THR A1 CG2 1 
ATOM 1180 N N   . PRO A 1 187 ? 74.123  61.194  -39.355 1.00 6.29   ? 187 PRO A1 N   1 
ATOM 1181 C CA  . PRO A 1 187 ? 74.797  59.895  -39.430 1.00 7.21   ? 187 PRO A1 CA  1 
ATOM 1182 C C   . PRO A 1 187 ? 76.301  60.087  -39.526 1.00 7.68   ? 187 PRO A1 C   1 
ATOM 1183 O O   . PRO A 1 187 ? 76.798  60.811  -40.391 1.00 10.17  ? 187 PRO A1 O   1 
ATOM 1184 C CB  . PRO A 1 187 ? 74.226  59.269  -40.703 1.00 6.70   ? 187 PRO A1 CB  1 
ATOM 1185 C CG  . PRO A 1 187 ? 73.785  60.423  -41.527 1.00 6.77   ? 187 PRO A1 CG  1 
ATOM 1186 C CD  . PRO A 1 187 ? 73.386  61.511  -40.588 1.00 6.85   ? 187 PRO A1 CD  1 
ATOM 1187 N N   . ALA A 1 188 ? 77.024  59.429  -38.630 1.00 6.49   ? 188 ALA A1 N   1 
ATOM 1188 C CA  . ALA A 1 188 ? 78.416  59.757  -38.377 1.00 6.16   ? 188 ALA A1 CA  1 
ATOM 1189 C C   . ALA A 1 188 ? 79.400  58.850  -39.092 1.00 7.22   ? 188 ALA A1 C   1 
ATOM 1190 O O   . ALA A 1 188 ? 80.591  58.907  -38.791 1.00 8.87   ? 188 ALA A1 O   1 
ATOM 1191 C CB  . ALA A 1 188 ? 78.681  59.731  -36.876 1.00 4.47   ? 188 ALA A1 CB  1 
ATOM 1192 N N   . ALA A 1 189 ? 78.945  58.015  -40.019 1.00 8.01   ? 189 ALA A1 N   1 
ATOM 1193 C CA  . ALA A 1 189 ? 79.875  57.298  -40.876 1.00 7.42   ? 189 ALA A1 CA  1 
ATOM 1194 C C   . ALA A 1 189 ? 80.187  58.053  -42.154 1.00 8.22   ? 189 ALA A1 C   1 
ATOM 1195 O O   . ALA A 1 189 ? 81.023  57.593  -42.935 1.00 9.38   ? 189 ALA A1 O   1 
ATOM 1196 C CB  . ALA A 1 189 ? 79.333  55.916  -41.221 1.00 8.37   ? 189 ALA A1 CB  1 
ATOM 1197 N N   . MET A 1 190 ? 79.527  59.189  -42.389 1.00 8.83   ? 190 MET A1 N   1 
ATOM 1198 C CA  . MET A 1 190 ? 79.912  60.058  -43.493 1.00 9.66   ? 190 MET A1 CA  1 
ATOM 1199 C C   . MET A 1 190 ? 81.107  60.917  -43.113 1.00 8.78   ? 190 MET A1 C   1 
ATOM 1200 O O   . MET A 1 190 ? 81.711  61.563  -43.973 1.00 8.99   ? 190 MET A1 O   1 
ATOM 1201 C CB  . MET A 1 190 ? 78.737  60.938  -43.906 1.00 13.72  ? 190 MET A1 CB  1 
ATOM 1202 C CG  . MET A 1 190 ? 78.485  62.109  -42.964 1.00 20.53  ? 190 MET A1 CG  1 
ATOM 1203 S SD  . MET A 1 190 ? 76.937  62.985  -43.273 1.00 27.79  ? 190 MET A1 SD  1 
ATOM 1204 C CE  . MET A 1 190 ? 77.408  64.015  -44.655 1.00 24.66  ? 190 MET A1 CE  1 
ATOM 1205 N N   . ARG A 1 191 ? 81.442  60.958  -41.828 1.00 7.66   ? 191 ARG A1 N   1 
ATOM 1206 C CA  . ARG A 1 191 ? 82.595  61.685  -41.328 1.00 7.67   ? 191 ARG A1 CA  1 
ATOM 1207 C C   . ARG A 1 191 ? 83.662  60.767  -40.769 1.00 8.84   ? 191 ARG A1 C   1 
ATOM 1208 O O   . ARG A 1 191 ? 84.671  61.264  -40.262 1.00 12.39  ? 191 ARG A1 O   1 
ATOM 1209 C CB  . ARG A 1 191 ? 82.169  62.675  -40.251 1.00 6.52   ? 191 ARG A1 CB  1 
ATOM 1210 C CG  . ARG A 1 191 ? 81.349  63.818  -40.764 1.00 6.58   ? 191 ARG A1 CG  1 
ATOM 1211 C CD  . ARG A 1 191 ? 82.126  64.660  -41.732 1.00 7.77   ? 191 ARG A1 CD  1 
ATOM 1212 N NE  . ARG A 1 191 ? 81.288  65.713  -42.280 1.00 9.31   ? 191 ARG A1 NE  1 
ATOM 1213 C CZ  . ARG A 1 191 ? 81.719  66.654  -43.106 1.00 10.38  ? 191 ARG A1 CZ  1 
ATOM 1214 N NH1 . ARG A 1 191 ? 82.985  66.679  -43.485 1.00 12.55  ? 191 ARG A1 NH1 1 
ATOM 1215 N NH2 . ARG A 1 191 ? 80.879  67.569  -43.558 1.00 9.15   ? 191 ARG A1 NH2 1 
ATOM 1216 N N   . SER A 1 192 ? 83.452  59.451  -40.861 1.00 8.40   ? 192 SER A1 N   1 
ATOM 1217 C CA  . SER A 1 192 ? 84.338  58.416  -40.320 1.00 7.58   ? 192 SER A1 CA  1 
ATOM 1218 C C   . SER A 1 192 ? 84.584  58.600  -38.827 1.00 7.39   ? 192 SER A1 C   1 
ATOM 1219 O O   . SER A 1 192 ? 85.700  58.431  -38.335 1.00 8.70   ? 192 SER A1 O   1 
ATOM 1220 C CB  . SER A 1 192 ? 85.661  58.351  -41.086 1.00 7.90   ? 192 SER A1 CB  1 
ATOM 1221 O OG  . SER A 1 192 ? 86.537  57.424  -40.482 1.00 11.66  ? 192 SER A1 OG  1 
ATOM 1222 N N   . GLU A 1 193 ? 83.528  58.969  -38.097 1.00 8.22   ? 193 GLU A1 N   1 
ATOM 1223 C CA  . GLU A 1 193 ? 83.584  59.113  -36.642 1.00 10.14  ? 193 GLU A1 CA  1 
ATOM 1224 C C   . GLU A 1 193 ? 82.549  58.166  -36.052 1.00 11.44  ? 193 GLU A1 C   1 
ATOM 1225 O O   . GLU A 1 193 ? 81.451  58.572  -35.689 1.00 14.39  ? 193 GLU A1 O   1 
ATOM 1226 C CB  . GLU A 1 193 ? 83.333  60.554  -36.208 1.00 9.70   ? 193 GLU A1 CB  1 
ATOM 1227 C CG  . GLU A 1 193 ? 83.913  61.613  -37.104 1.00 10.82  ? 193 GLU A1 CG  1 
ATOM 1228 C CD  . GLU A 1 193 ? 84.255  62.889  -36.365 1.00 12.27  ? 193 GLU A1 CD  1 
ATOM 1229 O OE1 . GLU A 1 193 ? 85.194  63.588  -36.798 1.00 12.00  ? 193 GLU A1 OE1 1 
ATOM 1230 O OE2 . GLU A 1 193 ? 83.590  63.193  -35.351 1.00 13.03  ? 193 GLU A1 OE2 1 
ATOM 1231 N N   . THR A 1 194 ? 82.915  56.905  -35.913 1.00 12.24  ? 194 THR A1 N   1 
ATOM 1232 C CA  . THR A 1 194 ? 82.031  55.878  -35.393 1.00 11.87  ? 194 THR A1 CA  1 
ATOM 1233 C C   . THR A 1 194 ? 82.769  55.294  -34.186 1.00 12.45  ? 194 THR A1 C   1 
ATOM 1234 O O   . THR A 1 194 ? 83.854  55.762  -33.835 1.00 14.52  ? 194 THR A1 O   1 
ATOM 1235 C CB  . THR A 1 194 ? 81.713  54.873  -36.519 1.00 11.53  ? 194 THR A1 CB  1 
ATOM 1236 O OG1 . THR A 1 194 ? 81.309  55.609  -37.672 1.00 13.11  ? 194 THR A1 OG1 1 
ATOM 1237 C CG2 . THR A 1 194 ? 80.521  53.997  -36.216 1.00 10.50  ? 194 THR A1 CG2 1 
ATOM 1238 N N   . LEU A 1 195 ? 82.191  54.312  -33.504 1.00 10.36  ? 195 LEU A1 N   1 
ATOM 1239 C CA  . LEU A 1 195 ? 82.983  53.511  -32.591 1.00 7.54   ? 195 LEU A1 CA  1 
ATOM 1240 C C   . LEU A 1 195 ? 83.997  52.696  -33.381 1.00 7.30   ? 195 LEU A1 C   1 
ATOM 1241 O O   . LEU A 1 195 ? 83.815  52.426  -34.568 1.00 8.24   ? 195 LEU A1 O   1 
ATOM 1242 C CB  . LEU A 1 195 ? 82.090  52.590  -31.768 1.00 5.61   ? 195 LEU A1 CB  1 
ATOM 1243 C CG  . LEU A 1 195 ? 81.025  53.250  -30.900 1.00 3.57   ? 195 LEU A1 CG  1 
ATOM 1244 C CD1 . LEU A 1 195 ? 79.961  52.253  -30.606 1.00 2.67   ? 195 LEU A1 CD1 1 
ATOM 1245 C CD2 . LEU A 1 195 ? 81.602  53.781  -29.614 1.00 3.81   ? 195 LEU A1 CD2 1 
ATOM 1246 N N   . GLY A 1 196 ? 85.074  52.307  -32.709 1.00 5.73   ? 196 GLY A1 N   1 
ATOM 1247 C CA  . GLY A 1 196 ? 86.160  51.625  -33.377 1.00 7.03   ? 196 GLY A1 CA  1 
ATOM 1248 C C   . GLY A 1 196 ? 85.780  50.247  -33.877 1.00 6.59   ? 196 GLY A1 C   1 
ATOM 1249 O O   . GLY A 1 196 ? 84.746  49.680  -33.533 1.00 9.22   ? 196 GLY A1 O   1 
ATOM 1250 N N   . PHE A 1 197 ? 86.638  49.700  -34.717 1.00 5.26   ? 197 PHE A1 N   1 
ATOM 1251 C CA  . PHE A 1 197 ? 86.296  48.470  -35.402 1.00 4.71   ? 197 PHE A1 CA  1 
ATOM 1252 C C   . PHE A 1 197 ? 86.924  47.241  -34.769 1.00 4.14   ? 197 PHE A1 C   1 
ATOM 1253 O O   . PHE A 1 197 ? 86.648  46.127  -35.220 1.00 3.68   ? 197 PHE A1 O   1 
ATOM 1254 C CB  . PHE A 1 197 ? 86.710  48.555  -36.875 1.00 4.44   ? 197 PHE A1 CB  1 
ATOM 1255 C CG  . PHE A 1 197 ? 85.858  49.479  -37.712 1.00 3.65   ? 197 PHE A1 CG  1 
ATOM 1256 C CD1 . PHE A 1 197 ? 84.699  50.043  -37.215 1.00 2.92   ? 197 PHE A1 CD1 1 
ATOM 1257 C CD2 . PHE A 1 197 ? 86.228  49.777  -38.998 1.00 2.78   ? 197 PHE A1 CD2 1 
ATOM 1258 C CE1 . PHE A 1 197 ? 83.939  50.886  -37.981 1.00 2.00   ? 197 PHE A1 CE1 1 
ATOM 1259 C CE2 . PHE A 1 197 ? 85.462  50.616  -39.762 1.00 2.13   ? 197 PHE A1 CE2 1 
ATOM 1260 C CZ  . PHE A 1 197 ? 84.323  51.173  -39.247 1.00 2.08   ? 197 PHE A1 CZ  1 
ATOM 1261 N N   . TYR A 1 198 ? 87.751  47.411  -33.741 1.00 4.89   ? 198 TYR A1 N   1 
ATOM 1262 C CA  . TYR A 1 198 ? 88.418  46.319  -33.061 1.00 6.73   ? 198 TYR A1 CA  1 
ATOM 1263 C C   . TYR A 1 198 ? 87.868  46.182  -31.655 1.00 6.42   ? 198 TYR A1 C   1 
ATOM 1264 O O   . TYR A 1 198 ? 87.768  47.187  -30.944 1.00 8.36   ? 198 TYR A1 O   1 
ATOM 1265 C CB  . TYR A 1 198 ? 89.923  46.559  -33.004 1.00 7.35   ? 198 TYR A1 CB  1 
ATOM 1266 C CG  . TYR A 1 198 ? 90.495  47.196  -34.243 1.00 9.63   ? 198 TYR A1 CG  1 
ATOM 1267 C CD1 . TYR A 1 198 ? 90.770  48.548  -34.275 1.00 8.84   ? 198 TYR A1 CD1 1 
ATOM 1268 C CD2 . TYR A 1 198 ? 90.763  46.446  -35.378 1.00 10.42  ? 198 TYR A1 CD2 1 
ATOM 1269 C CE1 . TYR A 1 198 ? 91.286  49.138  -35.387 1.00 11.49  ? 198 TYR A1 CE1 1 
ATOM 1270 C CE2 . TYR A 1 198 ? 91.282  47.034  -36.502 1.00 10.32  ? 198 TYR A1 CE2 1 
ATOM 1271 C CZ  . TYR A 1 198 ? 91.545  48.384  -36.495 1.00 11.83  ? 198 TYR A1 CZ  1 
ATOM 1272 O OH  . TYR A 1 198 ? 92.068  49.007  -37.600 1.00 13.78  ? 198 TYR A1 OH  1 
ATOM 1273 N N   . PRO A 1 199 ? 87.492  44.974  -31.229 1.00 4.55   ? 199 PRO A1 N   1 
ATOM 1274 C CA  . PRO A 1 199 ? 86.881  44.813  -29.900 1.00 4.57   ? 199 PRO A1 CA  1 
ATOM 1275 C C   . PRO A 1 199 ? 87.806  45.085  -28.727 1.00 6.20   ? 199 PRO A1 C   1 
ATOM 1276 O O   . PRO A 1 199 ? 87.329  45.520  -27.675 1.00 7.34   ? 199 PRO A1 O   1 
ATOM 1277 C CB  . PRO A 1 199 ? 86.440  43.349  -29.909 1.00 2.70   ? 199 PRO A1 CB  1 
ATOM 1278 C CG  . PRO A 1 199 ? 86.234  43.035  -31.326 1.00 2.60   ? 199 PRO A1 CG  1 
ATOM 1279 C CD  . PRO A 1 199 ? 87.266  43.796  -32.076 1.00 3.30   ? 199 PRO A1 CD  1 
ATOM 1280 N N   . TRP A 1 200 ? 89.103  44.835  -28.864 1.00 6.62   ? 200 TRP A1 N   1 
ATOM 1281 C CA  . TRP A 1 200 ? 90.049  44.938  -27.763 1.00 6.46   ? 200 TRP A1 CA  1 
ATOM 1282 C C   . TRP A 1 200 ? 90.620  46.335  -27.594 1.00 7.39   ? 200 TRP A1 C   1 
ATOM 1283 O O   . TRP A 1 200 ? 91.505  46.527  -26.757 1.00 8.10   ? 200 TRP A1 O   1 
ATOM 1284 C CB  . TRP A 1 200 ? 91.200  43.955  -27.968 1.00 4.97   ? 200 TRP A1 CB  1 
ATOM 1285 C CG  . TRP A 1 200 ? 91.788  44.032  -29.325 1.00 5.19   ? 200 TRP A1 CG  1 
ATOM 1286 C CD1 . TRP A 1 200 ? 92.817  44.817  -29.722 1.00 4.72   ? 200 TRP A1 CD1 1 
ATOM 1287 C CD2 . TRP A 1 200 ? 91.373  43.301  -30.476 1.00 5.94   ? 200 TRP A1 CD2 1 
ATOM 1288 N NE1 . TRP A 1 200 ? 93.073  44.626  -31.050 1.00 6.76   ? 200 TRP A1 NE1 1 
ATOM 1289 C CE2 . TRP A 1 200 ? 92.197  43.694  -31.536 1.00 6.07   ? 200 TRP A1 CE2 1 
ATOM 1290 C CE3 . TRP A 1 200 ? 90.385  42.349  -30.711 1.00 4.76   ? 200 TRP A1 CE3 1 
ATOM 1291 C CZ2 . TRP A 1 200 ? 92.066  43.167  -32.809 1.00 4.36   ? 200 TRP A1 CZ2 1 
ATOM 1292 C CZ3 . TRP A 1 200 ? 90.263  41.825  -31.970 1.00 3.60   ? 200 TRP A1 CZ3 1 
ATOM 1293 C CH2 . TRP A 1 200 ? 91.088  42.242  -33.006 1.00 4.33   ? 200 TRP A1 CH2 1 
ATOM 1294 N N   . LYS A 1 201 ? 90.143  47.302  -28.354 1.00 6.89   ? 201 LYS A1 N   1 
ATOM 1295 C CA  . LYS A 1 201 ? 90.688  48.640  -28.339 1.00 7.49   ? 201 LYS A1 CA  1 
ATOM 1296 C C   . LYS A 1 201 ? 89.652  49.617  -27.811 1.00 7.26   ? 201 LYS A1 C   1 
ATOM 1297 O O   . LYS A 1 201 ? 88.509  49.594  -28.281 1.00 8.25   ? 201 LYS A1 O   1 
ATOM 1298 C CB  . LYS A 1 201 ? 91.116  49.038  -29.748 1.00 11.21  ? 201 LYS A1 CB  1 
ATOM 1299 C CG  . LYS A 1 201 ? 91.973  50.273  -29.823 1.00 17.48  ? 201 LYS A1 CG  1 
ATOM 1300 C CD  . LYS A 1 201 ? 92.238  50.648  -31.267 1.00 22.92  ? 201 LYS A1 CD  1 
ATOM 1301 C CE  . LYS A 1 201 ? 93.025  51.937  -31.364 1.00 25.34  ? 201 LYS A1 CE  1 
ATOM 1302 N NZ  . LYS A 1 201 ? 93.426  52.233  -32.761 1.00 28.37  ? 201 LYS A1 NZ  1 
ATOM 1303 N N   . PRO A 1 202 ? 89.987  50.451  -26.828 1.00 5.35   ? 202 PRO A1 N   1 
ATOM 1304 C CA  . PRO A 1 202 ? 89.029  51.452  -26.355 1.00 4.53   ? 202 PRO A1 CA  1 
ATOM 1305 C C   . PRO A 1 202 ? 88.765  52.523  -27.394 1.00 5.00   ? 202 PRO A1 C   1 
ATOM 1306 O O   . PRO A 1 202 ? 89.616  52.842  -28.225 1.00 6.07   ? 202 PRO A1 O   1 
ATOM 1307 C CB  . PRO A 1 202 ? 89.715  52.039  -25.120 1.00 3.82   ? 202 PRO A1 CB  1 
ATOM 1308 C CG  . PRO A 1 202 ? 90.612  50.981  -24.670 1.00 3.91   ? 202 PRO A1 CG  1 
ATOM 1309 C CD  . PRO A 1 202 ? 91.122  50.326  -25.905 1.00 4.76   ? 202 PRO A1 CD  1 
ATOM 1310 N N   . THR A 1 203 ? 87.565  53.081  -27.338 1.00 4.18   ? 203 THR A1 N   1 
ATOM 1311 C CA  . THR A 1 203 ? 87.079  54.009  -28.346 1.00 3.42   ? 203 THR A1 CA  1 
ATOM 1312 C C   . THR A 1 203 ? 86.575  55.289  -27.688 1.00 4.82   ? 203 THR A1 C   1 
ATOM 1313 O O   . THR A 1 203 ? 86.634  55.450  -26.472 1.00 7.68   ? 203 THR A1 O   1 
ATOM 1314 C CB  . THR A 1 203 ? 85.995  53.346  -29.193 1.00 3.17   ? 203 THR A1 CB  1 
ATOM 1315 O OG1 . THR A 1 203 ? 85.354  54.335  -29.999 1.00 3.98   ? 203 THR A1 OG1 1 
ATOM 1316 C CG2 . THR A 1 203 ? 84.985  52.675  -28.325 1.00 3.51   ? 203 THR A1 CG2 1 
ATOM 1317 N N   . ILE A 1 204 ? 86.091  56.217  -28.506 1.00 4.30   ? 204 ILE A1 N   1 
ATOM 1318 C CA  . ILE A 1 204 ? 85.638  57.520  -28.021 1.00 3.08   ? 204 ILE A1 CA  1 
ATOM 1319 C C   . ILE A 1 204 ? 84.295  57.839  -28.665 1.00 3.23   ? 204 ILE A1 C   1 
ATOM 1320 O O   . ILE A 1 204 ? 83.979  57.335  -29.752 1.00 4.22   ? 204 ILE A1 O   1 
ATOM 1321 C CB  . ILE A 1 204 ? 86.667  58.634  -28.329 1.00 2.00   ? 204 ILE A1 CB  1 
ATOM 1322 C CG1 . ILE A 1 204 ? 87.070  58.601  -29.797 1.00 2.00   ? 204 ILE A1 CG1 1 
ATOM 1323 C CG2 . ILE A 1 204 ? 87.871  58.542  -27.413 1.00 2.54   ? 204 ILE A1 CG2 1 
ATOM 1324 C CD1 . ILE A 1 204 ? 88.083  59.641  -30.158 1.00 2.00   ? 204 ILE A1 CD1 1 
ATOM 1325 N N   . PRO A 1 205 ? 83.465  58.676  -28.008 1.00 3.25   ? 205 PRO A1 N   1 
ATOM 1326 C CA  . PRO A 1 205 ? 82.260  59.168  -28.677 1.00 5.58   ? 205 PRO A1 CA  1 
ATOM 1327 C C   . PRO A 1 205 ? 82.506  60.485  -29.391 1.00 7.63   ? 205 PRO A1 C   1 
ATOM 1328 O O   . PRO A 1 205 ? 83.492  61.175  -29.120 1.00 10.73  ? 205 PRO A1 O   1 
ATOM 1329 C CB  . PRO A 1 205 ? 81.262  59.341  -27.530 1.00 4.72   ? 205 PRO A1 CB  1 
ATOM 1330 C CG  . PRO A 1 205 ? 82.048  59.290  -26.286 1.00 3.27   ? 205 PRO A1 CG  1 
ATOM 1331 C CD  . PRO A 1 205 ? 83.493  59.112  -26.607 1.00 3.24   ? 205 PRO A1 CD  1 
ATOM 1332 N N   . THR A 1 206 ? 81.615  60.851  -30.283 1.00 9.46   ? 206 THR A1 N   1 
ATOM 1333 C CA  . THR A 1 206 ? 81.923  61.981  -31.132 1.00 10.60  ? 206 THR A1 CA  1 
ATOM 1334 C C   . THR A 1 206 ? 81.204  63.227  -30.646 1.00 8.36   ? 206 THR A1 C   1 
ATOM 1335 O O   . THR A 1 206 ? 80.010  63.163  -30.351 1.00 8.09   ? 206 THR A1 O   1 
ATOM 1336 C CB  . THR A 1 206 ? 81.509  61.693  -32.571 1.00 12.39  ? 206 THR A1 CB  1 
ATOM 1337 O OG1 . THR A 1 206 ? 80.089  61.798  -32.687 1.00 14.74  ? 206 THR A1 OG1 1 
ATOM 1338 C CG2 . THR A 1 206 ? 81.884  60.279  -32.894 1.00 15.26  ? 206 THR A1 CG2 1 
ATOM 1339 N N   . PRO A 1 207 ? 81.881  64.373  -30.603 1.00 7.07   ? 207 PRO A1 N   1 
ATOM 1340 C CA  . PRO A 1 207 ? 81.293  65.574  -29.994 1.00 7.87   ? 207 PRO A1 CA  1 
ATOM 1341 C C   . PRO A 1 207 ? 80.211  66.201  -30.850 1.00 7.74   ? 207 PRO A1 C   1 
ATOM 1342 O O   . PRO A 1 207 ? 80.522  67.029  -31.709 1.00 9.85   ? 207 PRO A1 O   1 
ATOM 1343 C CB  . PRO A 1 207 ? 82.492  66.514  -29.842 1.00 7.37   ? 207 PRO A1 CB  1 
ATOM 1344 C CG  . PRO A 1 207 ? 83.692  65.664  -30.052 1.00 6.17   ? 207 PRO A1 CG  1 
ATOM 1345 C CD  . PRO A 1 207 ? 83.276  64.603  -30.993 1.00 6.30   ? 207 PRO A1 CD  1 
ATOM 1346 N N   . TRP A 1 208 ? 78.964  65.766  -30.637 1.00 5.28   ? 208 TRP A1 N   1 
ATOM 1347 C CA  . TRP A 1 208 ? 77.827  66.041  -31.509 1.00 3.95   ? 208 TRP A1 CA  1 
ATOM 1348 C C   . TRP A 1 208 ? 77.613  67.529  -31.746 1.00 4.00   ? 208 TRP A1 C   1 
ATOM 1349 O O   . TRP A 1 208 ? 77.915  68.375  -30.904 1.00 5.06   ? 208 TRP A1 O   1 
ATOM 1350 C CB  . TRP A 1 208 ? 76.561  65.431  -30.906 1.00 3.56   ? 208 TRP A1 CB  1 
ATOM 1351 C CG  . TRP A 1 208 ? 75.377  65.459  -31.793 1.00 3.46   ? 208 TRP A1 CG  1 
ATOM 1352 C CD1 . TRP A 1 208 ? 75.223  64.798  -32.968 1.00 3.87   ? 208 TRP A1 CD1 1 
ATOM 1353 C CD2 . TRP A 1 208 ? 74.169  66.190  -31.583 1.00 3.10   ? 208 TRP A1 CD2 1 
ATOM 1354 N NE1 . TRP A 1 208 ? 73.995  65.073  -33.509 1.00 4.55   ? 208 TRP A1 NE1 1 
ATOM 1355 C CE2 . TRP A 1 208 ? 73.329  65.927  -32.674 1.00 3.52   ? 208 TRP A1 CE2 1 
ATOM 1356 C CE3 . TRP A 1 208 ? 73.721  67.048  -30.582 1.00 2.46   ? 208 TRP A1 CE3 1 
ATOM 1357 C CZ2 . TRP A 1 208 ? 72.069  66.484  -32.788 1.00 2.80   ? 208 TRP A1 CZ2 1 
ATOM 1358 C CZ3 . TRP A 1 208 ? 72.471  67.600  -30.701 1.00 2.38   ? 208 TRP A1 CZ3 1 
ATOM 1359 C CH2 . TRP A 1 208 ? 71.662  67.321  -31.797 1.00 3.12   ? 208 TRP A1 CH2 1 
ATOM 1360 N N   . ARG A 1 209 ? 77.099  67.826  -32.933 1.00 3.34   ? 209 ARG A1 N   1 
ATOM 1361 C CA  . ARG A 1 209 ? 76.864  69.137  -33.505 1.00 2.40   ? 209 ARG A1 CA  1 
ATOM 1362 C C   . ARG A 1 209 ? 75.879  68.940  -34.637 1.00 2.61   ? 209 ARG A1 C   1 
ATOM 1363 O O   . ARG A 1 209 ? 75.689  67.816  -35.101 1.00 3.90   ? 209 ARG A1 O   1 
ATOM 1364 C CB  . ARG A 1 209 ? 78.154  69.788  -34.019 1.00 3.03   ? 209 ARG A1 CB  1 
ATOM 1365 C CG  . ARG A 1 209 ? 78.768  69.107  -35.226 1.00 2.16   ? 209 ARG A1 CG  1 
ATOM 1366 C CD  . ARG A 1 209 ? 79.768  68.054  -34.818 1.00 2.60   ? 209 ARG A1 CD  1 
ATOM 1367 N NE  . ARG A 1 209 ? 80.415  67.411  -35.944 1.00 3.95   ? 209 ARG A1 NE  1 
ATOM 1368 C CZ  . ARG A 1 209 ? 81.214  66.363  -35.826 1.00 4.52   ? 209 ARG A1 CZ  1 
ATOM 1369 N NH1 . ARG A 1 209 ? 81.475  65.869  -34.630 1.00 5.02   ? 209 ARG A1 NH1 1 
ATOM 1370 N NH2 . ARG A 1 209 ? 81.767  65.822  -36.895 1.00 5.37   ? 209 ARG A1 NH2 1 
ATOM 1371 N N   . TYR A 1 210 ? 75.242  70.022  -35.064 1.00 3.44   ? 210 TYR A1 N   1 
ATOM 1372 C CA  . TYR A 1 210 ? 74.308  69.944  -36.173 1.00 4.40   ? 210 TYR A1 CA  1 
ATOM 1373 C C   . TYR A 1 210 ? 74.314  71.257  -36.933 1.00 5.27   ? 210 TYR A1 C   1 
ATOM 1374 O O   . TYR A 1 210 ? 74.751  72.286  -36.424 1.00 6.42   ? 210 TYR A1 O   1 
ATOM 1375 C CB  . TYR A 1 210 ? 72.887  69.595  -35.710 1.00 3.21   ? 210 TYR A1 CB  1 
ATOM 1376 C CG  . TYR A 1 210 ? 72.267  70.556  -34.729 1.00 2.10   ? 210 TYR A1 CG  1 
ATOM 1377 C CD1 . TYR A 1 210 ? 71.420  71.567  -35.155 1.00 2.00   ? 210 TYR A1 CD1 1 
ATOM 1378 C CD2 . TYR A 1 210 ? 72.491  70.424  -33.373 1.00 2.00   ? 210 TYR A1 CD2 1 
ATOM 1379 C CE1 . TYR A 1 210 ? 70.855  72.435  -34.265 1.00 2.09   ? 210 TYR A1 CE1 1 
ATOM 1380 C CE2 . TYR A 1 210 ? 71.932  71.285  -32.480 1.00 2.63   ? 210 TYR A1 CE2 1 
ATOM 1381 C CZ  . TYR A 1 210 ? 71.117  72.282  -32.928 1.00 3.07   ? 210 TYR A1 CZ  1 
ATOM 1382 O OH  . TYR A 1 210 ? 70.558  73.130  -32.018 1.00 5.78   ? 210 TYR A1 OH  1 
ATOM 1383 N N   . TYR A 1 211 ? 73.803  71.207  -38.159 1.00 6.40   ? 211 TYR A1 N   1 
ATOM 1384 C CA  . TYR A 1 211 ? 73.832  72.348  -39.066 1.00 6.95   ? 211 TYR A1 CA  1 
ATOM 1385 C C   . TYR A 1 211 ? 72.813  73.391  -38.639 1.00 7.14   ? 211 TYR A1 C   1 
ATOM 1386 O O   . TYR A 1 211 ? 71.632  73.080  -38.473 1.00 7.64   ? 211 TYR A1 O   1 
ATOM 1387 C CB  . TYR A 1 211 ? 73.531  71.901  -40.491 1.00 6.97   ? 211 TYR A1 CB  1 
ATOM 1388 C CG  . TYR A 1 211 ? 74.686  71.298  -41.240 1.00 6.64   ? 211 TYR A1 CG  1 
ATOM 1389 C CD1 . TYR A 1 211 ? 75.798  72.049  -41.564 1.00 6.97   ? 211 TYR A1 CD1 1 
ATOM 1390 C CD2 . TYR A 1 211 ? 74.645  69.980  -41.649 1.00 5.82   ? 211 TYR A1 CD2 1 
ATOM 1391 C CE1 . TYR A 1 211 ? 76.841  71.494  -42.261 1.00 6.59   ? 211 TYR A1 CE1 1 
ATOM 1392 C CE2 . TYR A 1 211 ? 75.679  69.419  -42.338 1.00 5.47   ? 211 TYR A1 CE2 1 
ATOM 1393 C CZ  . TYR A 1 211 ? 76.773  70.180  -42.646 1.00 5.35   ? 211 TYR A1 CZ  1 
ATOM 1394 O OH  . TYR A 1 211 ? 77.802  69.608  -43.341 1.00 5.90   ? 211 TYR A1 OH  1 
ATOM 1395 N N   . PHE A 1 212 ? 73.264  74.624  -38.470 1.00 7.16   ? 212 PHE A1 N   1 
ATOM 1396 C CA  . PHE A 1 212 ? 72.368  75.758  -38.358 1.00 7.86   ? 212 PHE A1 CA  1 
ATOM 1397 C C   . PHE A 1 212 ? 72.103  76.288  -39.752 1.00 9.58   ? 212 PHE A1 C   1 
ATOM 1398 O O   . PHE A 1 212 ? 72.794  75.932  -40.700 1.00 12.63  ? 212 PHE A1 O   1 
ATOM 1399 C CB  . PHE A 1 212 ? 72.978  76.850  -37.487 1.00 5.46   ? 212 PHE A1 CB  1 
ATOM 1400 C CG  . PHE A 1 212 ? 71.974  77.776  -36.898 1.00 5.49   ? 212 PHE A1 CG  1 
ATOM 1401 C CD1 . PHE A 1 212 ? 71.029  77.306  -36.021 1.00 5.38   ? 212 PHE A1 CD1 1 
ATOM 1402 C CD2 . PHE A 1 212 ? 71.968  79.113  -37.226 1.00 6.36   ? 212 PHE A1 CD2 1 
ATOM 1403 C CE1 . PHE A 1 212 ? 70.103  78.146  -35.473 1.00 6.37   ? 212 PHE A1 CE1 1 
ATOM 1404 C CE2 . PHE A 1 212 ? 71.033  79.957  -36.685 1.00 7.42   ? 212 PHE A1 CE2 1 
ATOM 1405 C CZ  . PHE A 1 212 ? 70.101  79.470  -35.808 1.00 6.50   ? 212 PHE A1 CZ  1 
ATOM 1406 N N   . GLN A 1 213 ? 71.091  77.132  -39.879 1.00 9.14   ? 213 GLN A1 N   1 
ATOM 1407 C CA  . GLN A 1 213 ? 70.758  77.652  -41.193 1.00 9.44   ? 213 GLN A1 CA  1 
ATOM 1408 C C   . GLN A 1 213 ? 71.632  78.845  -41.545 1.00 9.44   ? 213 GLN A1 C   1 
ATOM 1409 O O   . GLN A 1 213 ? 71.986  79.662  -40.695 1.00 10.76  ? 213 GLN A1 O   1 
ATOM 1410 C CB  . GLN A 1 213 ? 69.292  78.049  -41.258 1.00 9.78   ? 213 GLN A1 CB  1 
ATOM 1411 C CG  . GLN A 1 213 ? 68.743  78.073  -42.662 1.00 9.41   ? 213 GLN A1 CG  1 
ATOM 1412 C CD  . GLN A 1 213 ? 68.681  79.465  -43.210 1.00 10.00  ? 213 GLN A1 CD  1 
ATOM 1413 O OE1 . GLN A 1 213 ? 68.852  80.432  -42.476 1.00 9.24   ? 213 GLN A1 OE1 1 
ATOM 1414 N NE2 . GLN A 1 213 ? 68.438  79.586  -44.505 1.00 11.87  ? 213 GLN A1 NE2 1 
ATOM 1415 N N   . TRP A 1 214 ? 71.993  78.926  -42.818 1.00 9.00   ? 214 TRP A1 N   1 
ATOM 1416 C CA  . TRP A 1 214 ? 72.749  80.054  -43.329 1.00 10.01  ? 214 TRP A1 CA  1 
ATOM 1417 C C   . TRP A 1 214 ? 72.351  80.267  -44.778 1.00 10.79  ? 214 TRP A1 C   1 
ATOM 1418 O O   . TRP A 1 214 ? 71.793  79.378  -45.419 1.00 9.78   ? 214 TRP A1 O   1 
ATOM 1419 C CB  . TRP A 1 214 ? 74.255  79.830  -43.191 1.00 10.71  ? 214 TRP A1 CB  1 
ATOM 1420 C CG  . TRP A 1 214 ? 74.853  78.927  -44.208 1.00 10.40  ? 214 TRP A1 CG  1 
ATOM 1421 C CD1 . TRP A 1 214 ? 75.480  79.294  -45.350 1.00 9.81   ? 214 TRP A1 CD1 1 
ATOM 1422 C CD2 . TRP A 1 214 ? 74.913  77.501  -44.161 1.00 11.21  ? 214 TRP A1 CD2 1 
ATOM 1423 N NE1 . TRP A 1 214 ? 75.909  78.190  -46.030 1.00 10.28  ? 214 TRP A1 NE1 1 
ATOM 1424 C CE2 . TRP A 1 214 ? 75.578  77.076  -45.312 1.00 11.20  ? 214 TRP A1 CE2 1 
ATOM 1425 C CE3 . TRP A 1 214 ? 74.469  76.545  -43.253 1.00 10.93  ? 214 TRP A1 CE3 1 
ATOM 1426 C CZ2 . TRP A 1 214 ? 75.802  75.740  -45.581 1.00 10.66  ? 214 TRP A1 CZ2 1 
ATOM 1427 C CZ3 . TRP A 1 214 ? 74.694  75.227  -43.519 1.00 9.90   ? 214 TRP A1 CZ3 1 
ATOM 1428 C CH2 . TRP A 1 214 ? 75.347  74.832  -44.673 1.00 10.61  ? 214 TRP A1 CH2 1 
ATOM 1429 N N   . ASP A 1 215 ? 72.611  81.473  -45.273 1.00 12.99  ? 215 ASP A1 N   1 
ATOM 1430 C CA  . ASP A 1 215 ? 72.447  81.818  -46.678 1.00 16.70  ? 215 ASP A1 CA  1 
ATOM 1431 C C   . ASP A 1 215 ? 73.792  82.277  -47.208 1.00 17.84  ? 215 ASP A1 C   1 
ATOM 1432 O O   . ASP A 1 215 ? 74.504  83.010  -46.520 1.00 18.73  ? 215 ASP A1 O   1 
ATOM 1433 C CB  . ASP A 1 215 ? 71.423  82.938  -46.875 1.00 20.63  ? 215 ASP A1 CB  1 
ATOM 1434 C CG  . ASP A 1 215 ? 69.998  82.501  -46.611 1.00 24.92  ? 215 ASP A1 CG  1 
ATOM 1435 O OD1 . ASP A 1 215 ? 69.784  81.438  -46.000 1.00 26.67  ? 215 ASP A1 OD1 1 
ATOM 1436 O OD2 . ASP A 1 215 ? 69.075  83.240  -47.012 1.00 27.26  ? 215 ASP A1 OD2 1 
ATOM 1437 N N   . ARG A 1 216 ? 74.137  81.860  -48.424 1.00 17.48  ? 216 ARG A1 N   1 
ATOM 1438 C CA  . ARG A 1 216 ? 75.358  82.334  -49.057 1.00 18.12  ? 216 ARG A1 CA  1 
ATOM 1439 C C   . ARG A 1 216 ? 75.240  82.198  -50.568 1.00 18.35  ? 216 ARG A1 C   1 
ATOM 1440 O O   . ARG A 1 216 ? 74.404  81.454  -51.084 1.00 20.77  ? 216 ARG A1 O   1 
ATOM 1441 C CB  . ARG A 1 216 ? 76.585  81.589  -48.541 1.00 17.95  ? 216 ARG A1 CB  1 
ATOM 1442 C CG  . ARG A 1 216 ? 76.854  80.285  -49.210 1.00 18.66  ? 216 ARG A1 CG  1 
ATOM 1443 C CD  . ARG A 1 216 ? 78.237  79.843  -48.856 1.00 18.21  ? 216 ARG A1 CD  1 
ATOM 1444 N NE  . ARG A 1 216 ? 79.209  80.882  -49.155 1.00 18.75  ? 216 ARG A1 NE  1 
ATOM 1445 C CZ  . ARG A 1 216 ? 80.089  80.799  -50.139 1.00 19.39  ? 216 ARG A1 CZ  1 
ATOM 1446 N NH1 . ARG A 1 216 ? 80.107  79.726  -50.899 1.00 18.00  ? 216 ARG A1 NH1 1 
ATOM 1447 N NH2 . ARG A 1 216 ? 80.947  81.776  -50.357 1.00 19.04  ? 216 ARG A1 NH2 1 
ATOM 1448 N N   . THR A 1 217 ? 76.093  82.940  -51.276 1.00 16.91  ? 217 THR A1 N   1 
ATOM 1449 C CA  . THR A 1 217 ? 76.135  82.936  -52.733 1.00 13.80  ? 217 THR A1 CA  1 
ATOM 1450 C C   . THR A 1 217 ? 77.575  82.847  -53.198 1.00 12.03  ? 217 THR A1 C   1 
ATOM 1451 O O   . THR A 1 217 ? 78.415  83.639  -52.769 1.00 10.81  ? 217 THR A1 O   1 
ATOM 1452 C CB  . THR A 1 217 ? 75.490  84.193  -53.320 1.00 14.02  ? 217 THR A1 CB  1 
ATOM 1453 O OG1 . THR A 1 217 ? 74.171  84.342  -52.795 1.00 15.98  ? 217 THR A1 OG1 1 
ATOM 1454 C CG2 . THR A 1 217 ? 75.405  84.097  -54.827 1.00 13.89  ? 217 THR A1 CG2 1 
ATOM 1455 N N   . LEU A 1 218 ? 77.854  81.893  -54.080 1.00 9.92   ? 218 LEU A1 N   1 
ATOM 1456 C CA  . LEU A 1 218 ? 79.172  81.731  -54.679 1.00 9.60   ? 218 LEU A1 CA  1 
ATOM 1457 C C   . LEU A 1 218 ? 78.995  81.624  -56.183 1.00 11.78  ? 218 LEU A1 C   1 
ATOM 1458 O O   . LEU A 1 218 ? 78.573  80.578  -56.684 1.00 14.76  ? 218 LEU A1 O   1 
ATOM 1459 C CB  . LEU A 1 218 ? 79.877  80.495  -54.135 1.00 6.53   ? 218 LEU A1 CB  1 
ATOM 1460 C CG  . LEU A 1 218 ? 81.284  80.239  -54.656 1.00 5.20   ? 218 LEU A1 CG  1 
ATOM 1461 C CD1 . LEU A 1 218 ? 82.164  81.413  -54.348 1.00 5.24   ? 218 LEU A1 CD1 1 
ATOM 1462 C CD2 . LEU A 1 218 ? 81.837  78.994  -54.028 1.00 3.78   ? 218 LEU A1 CD2 1 
ATOM 1463 N N   . ILE A 1 219 ? 79.304  82.695  -56.897 1.00 11.07  ? 219 ILE A1 N   1 
ATOM 1464 C CA  . ILE A 1 219 ? 79.227  82.683  -58.358 1.00 8.09   ? 219 ILE A1 CA  1 
ATOM 1465 C C   . ILE A 1 219 ? 80.487  82.021  -58.908 1.00 9.68   ? 219 ILE A1 C   1 
ATOM 1466 O O   . ILE A 1 219 ? 81.596  82.392  -58.499 1.00 10.48  ? 219 ILE A1 O   1 
ATOM 1467 C CB  . ILE A 1 219 ? 79.056  84.100  -58.892 1.00 5.94   ? 219 ILE A1 CB  1 
ATOM 1468 C CG1 . ILE A 1 219 ? 77.623  84.564  -58.674 1.00 3.36   ? 219 ILE A1 CG1 1 
ATOM 1469 C CG2 . ILE A 1 219 ? 79.379  84.189  -60.366 1.00 7.53   ? 219 ILE A1 CG2 1 
ATOM 1470 C CD1 . ILE A 1 219 ? 76.589  83.741  -59.376 1.00 2.54   ? 219 ILE A1 CD1 1 
ATOM 1471 N N   . PRO A 1 220 ? 80.360  81.038  -59.800 1.00 10.61  ? 220 PRO A1 N   1 
ATOM 1472 C CA  . PRO A 1 220 ? 81.534  80.294  -60.252 1.00 11.45  ? 220 PRO A1 CA  1 
ATOM 1473 C C   . PRO A 1 220 ? 82.441  81.121  -61.144 1.00 12.43  ? 220 PRO A1 C   1 
ATOM 1474 O O   . PRO A 1 220 ? 82.079  82.193  -61.634 1.00 14.66  ? 220 PRO A1 O   1 
ATOM 1475 C CB  . PRO A 1 220 ? 80.932  79.119  -61.028 1.00 10.13  ? 220 PRO A1 CB  1 
ATOM 1476 C CG  . PRO A 1 220 ? 79.528  79.072  -60.641 1.00 10.50  ? 220 PRO A1 CG  1 
ATOM 1477 C CD  . PRO A 1 220 ? 79.129  80.468  -60.355 1.00 10.81  ? 220 PRO A1 CD  1 
ATOM 1478 N N   . SER A 1 221 ? 83.634  80.582  -61.367 1.00 12.07  ? 221 SER A1 N   1 
ATOM 1479 C CA  . SER A 1 221 ? 84.718  81.305  -61.999 1.00 11.52  ? 221 SER A1 CA  1 
ATOM 1480 C C   . SER A 1 221 ? 85.789  80.310  -62.411 1.00 11.75  ? 221 SER A1 C   1 
ATOM 1481 O O   . SER A 1 221 ? 85.663  79.105  -62.194 1.00 11.10  ? 221 SER A1 O   1 
ATOM 1482 C CB  . SER A 1 221 ? 85.274  82.351  -61.044 1.00 10.30  ? 221 SER A1 CB  1 
ATOM 1483 O OG  . SER A 1 221 ? 85.726  81.726  -59.862 1.00 9.90   ? 221 SER A1 OG  1 
ATOM 1484 N N   . HIS A 1 222 ? 86.852  80.823  -63.015 1.00 13.25  ? 222 HIS A1 N   1 
ATOM 1485 C CA  . HIS A 1 222 ? 88.043  80.049  -63.313 1.00 13.85  ? 222 HIS A1 CA  1 
ATOM 1486 C C   . HIS A 1 222 ? 89.252  80.941  -63.084 1.00 15.58  ? 222 HIS A1 C   1 
ATOM 1487 O O   . HIS A 1 222 ? 89.148  82.011  -62.482 1.00 15.33  ? 222 HIS A1 O   1 
ATOM 1488 C CB  . HIS A 1 222 ? 88.011  79.481  -64.737 1.00 12.53  ? 222 HIS A1 CB  1 
ATOM 1489 C CG  . HIS A 1 222 ? 87.578  80.462  -65.777 1.00 12.99  ? 222 HIS A1 CG  1 
ATOM 1490 N ND1 . HIS A 1 222 ? 88.473  81.172  -66.544 1.00 13.79  ? 222 HIS A1 ND1 1 
ATOM 1491 C CD2 . HIS A 1 222 ? 86.348  80.845  -66.185 1.00 14.71  ? 222 HIS A1 CD2 1 
ATOM 1492 C CE1 . HIS A 1 222 ? 87.812  81.957  -67.374 1.00 14.62  ? 222 HIS A1 CE1 1 
ATOM 1493 N NE2 . HIS A 1 222 ? 86.521  81.777  -67.178 1.00 15.25  ? 222 HIS A1 NE2 1 
ATOM 1494 N N   . THR A 1 223 ? 90.412  80.502  -63.572 1.00 18.74  ? 223 THR A1 N   1 
ATOM 1495 C CA  . THR A 1 223 ? 91.644  81.228  -63.293 1.00 20.78  ? 223 THR A1 CA  1 
ATOM 1496 C C   . THR A 1 223 ? 91.747  82.524  -64.085 1.00 22.02  ? 223 THR A1 C   1 
ATOM 1497 O O   . THR A 1 223 ? 92.513  83.415  -63.710 1.00 23.36  ? 223 THR A1 O   1 
ATOM 1498 C CB  . THR A 1 223 ? 92.845  80.336  -63.580 1.00 21.69  ? 223 THR A1 CB  1 
ATOM 1499 O OG1 . THR A 1 223 ? 92.611  79.611  -64.789 1.00 23.62  ? 223 THR A1 OG1 1 
ATOM 1500 C CG2 . THR A 1 223 ? 93.048  79.359  -62.451 1.00 22.42  ? 223 THR A1 CG2 1 
ATOM 1501 N N   . GLY A 1 224 ? 90.988  82.658  -65.162 1.00 23.01  ? 224 GLY A1 N   1 
ATOM 1502 C CA  . GLY A 1 224 ? 91.102  83.819  -66.014 1.00 25.93  ? 224 GLY A1 CA  1 
ATOM 1503 C C   . GLY A 1 224 ? 89.904  84.741  -66.083 1.00 26.18  ? 224 GLY A1 C   1 
ATOM 1504 O O   . GLY A 1 224 ? 89.737  85.419  -67.101 1.00 25.90  ? 224 GLY A1 O   1 
ATOM 1505 N N   . THR A 1 225 ? 89.060  84.793  -65.058 1.00 28.33  ? 225 THR A1 N   1 
ATOM 1506 C CA  . THR A 1 225 ? 87.955  85.739  -65.080 1.00 29.67  ? 225 THR A1 CA  1 
ATOM 1507 C C   . THR A 1 225 ? 88.445  87.146  -64.770 1.00 32.35  ? 225 THR A1 C   1 
ATOM 1508 O O   . THR A 1 225 ? 89.401  87.348  -64.020 1.00 31.93  ? 225 THR A1 O   1 
ATOM 1509 C CB  . THR A 1 225 ? 86.868  85.352  -64.079 1.00 28.28  ? 225 THR A1 CB  1 
ATOM 1510 O OG1 . THR A 1 225 ? 87.339  85.565  -62.746 1.00 27.67  ? 225 THR A1 OG1 1 
ATOM 1511 C CG2 . THR A 1 225 ? 86.460  83.920  -64.252 1.00 28.23  ? 225 THR A1 CG2 1 
ATOM 1512 N N   . SER A 1 226 ? 87.771  88.126  -65.359 1.00 36.71  ? 226 SER A1 N   1 
ATOM 1513 C CA  . SER A 1 226 ? 88.036  89.528  -65.093 1.00 39.28  ? 226 SER A1 CA  1 
ATOM 1514 C C   . SER A 1 226 ? 87.092  90.011  -64.004 1.00 37.74  ? 226 SER A1 C   1 
ATOM 1515 O O   . SER A 1 226 ? 85.882  89.780  -64.070 1.00 37.91  ? 226 SER A1 O   1 
ATOM 1516 C CB  . SER A 1 226 ? 87.863  90.376  -66.352 1.00 41.49  ? 226 SER A1 CB  1 
ATOM 1517 O OG  . SER A 1 226 ? 86.509  90.409  -66.759 1.00 45.82  ? 226 SER A1 OG  1 
ATOM 1518 N N   . GLY A 1 227 ? 87.650  90.663  -62.994 1.00 37.04  ? 227 GLY A1 N   1 
ATOM 1519 C CA  . GLY A 1 227 ? 86.836  91.166  -61.910 1.00 35.78  ? 227 GLY A1 CA  1 
ATOM 1520 C C   . GLY A 1 227 ? 86.751  90.197  -60.753 1.00 34.10  ? 227 GLY A1 C   1 
ATOM 1521 O O   . GLY A 1 227 ? 87.667  89.397  -60.537 1.00 34.08  ? 227 GLY A1 O   1 
ATOM 1522 N N   . THR A 1 228 ? 85.659  90.261  -60.000 1.00 31.78  ? 228 THR A1 N   1 
ATOM 1523 C CA  . THR A 1 228 ? 85.481  89.401  -58.840 1.00 30.59  ? 228 THR A1 CA  1 
ATOM 1524 C C   . THR A 1 228 ? 84.046  88.895  -58.788 1.00 28.31  ? 228 THR A1 C   1 
ATOM 1525 O O   . THR A 1 228 ? 83.113  89.698  -58.665 1.00 28.00  ? 228 THR A1 O   1 
ATOM 1526 C CB  . THR A 1 228 ? 85.816  90.145  -57.545 1.00 32.10  ? 228 THR A1 CB  1 
ATOM 1527 O OG1 . THR A 1 228 ? 86.969  90.973  -57.740 1.00 33.07  ? 228 THR A1 OG1 1 
ATOM 1528 C CG2 . THR A 1 228 ? 86.102  89.159  -56.424 1.00 34.14  ? 228 THR A1 CG2 1 
ATOM 1529 N N   . PRO A 1 229 ? 83.826  87.588  -58.907 1.00 26.13  ? 229 PRO A1 N   1 
ATOM 1530 C CA  . PRO A 1 229 ? 82.493  87.042  -58.650 1.00 24.60  ? 229 PRO A1 CA  1 
ATOM 1531 C C   . PRO A 1 229 ? 82.159  87.136  -57.173 1.00 23.29  ? 229 PRO A1 C   1 
ATOM 1532 O O   . PRO A 1 229 ? 83.048  87.192  -56.321 1.00 22.74  ? 229 PRO A1 O   1 
ATOM 1533 C CB  . PRO A 1 229 ? 82.613  85.584  -59.102 1.00 24.04  ? 229 PRO A1 CB  1 
ATOM 1534 C CG  . PRO A 1 229 ? 83.790  85.562  -59.998 1.00 24.86  ? 229 PRO A1 CG  1 
ATOM 1535 C CD  . PRO A 1 229 ? 84.735  86.565  -59.440 1.00 25.29  ? 229 PRO A1 CD  1 
ATOM 1536 N N   . THR A 1 230 ? 80.864  87.163  -56.871 1.00 20.93  ? 230 THR A1 N   1 
ATOM 1537 C CA  . THR A 1 230 ? 80.456  87.423  -55.500 1.00 18.79  ? 230 THR A1 CA  1 
ATOM 1538 C C   . THR A 1 230 ? 80.648  86.180  -54.637 1.00 16.78  ? 230 THR A1 C   1 
ATOM 1539 O O   . THR A 1 230 ? 80.515  85.047  -55.102 1.00 15.53  ? 230 THR A1 O   1 
ATOM 1540 C CB  . THR A 1 230 ? 79.012  87.931  -55.436 1.00 19.07  ? 230 THR A1 CB  1 
ATOM 1541 O OG1 . THR A 1 230 ? 78.669  88.221  -54.079 1.00 21.40  ? 230 THR A1 OG1 1 
ATOM 1542 C CG2 . THR A 1 230 ? 78.038  86.940  -55.969 1.00 21.76  ? 230 THR A1 CG2 1 
ATOM 1543 N N   . ASN A 1 231 ? 81.027  86.412  -53.387 1.00 14.27  ? 231 ASN A1 N   1 
ATOM 1544 C CA  . ASN A 1 231 ? 81.377  85.375  -52.431 1.00 13.75  ? 231 ASN A1 CA  1 
ATOM 1545 C C   . ASN A 1 231 ? 80.804  85.707  -51.064 1.00 14.13  ? 231 ASN A1 C   1 
ATOM 1546 O O   . ASN A 1 231 ? 81.490  85.590  -50.054 1.00 14.94  ? 231 ASN A1 O   1 
ATOM 1547 C CB  . ASN A 1 231 ? 82.894  85.220  -52.353 1.00 13.18  ? 231 ASN A1 CB  1 
ATOM 1548 C CG  . ASN A 1 231 ? 83.326  83.822  -51.993 1.00 12.86  ? 231 ASN A1 CG  1 
ATOM 1549 O OD1 . ASN A 1 231 ? 82.684  83.146  -51.197 1.00 15.92  ? 231 ASN A1 OD1 1 
ATOM 1550 N ND2 . ASN A 1 231 ? 84.426  83.381  -52.577 1.00 12.05  ? 231 ASN A1 ND2 1 
ATOM 1551 N N   . ILE A 1 232 ? 79.560  86.141  -51.021 1.00 13.59  ? 232 ILE A1 N   1 
ATOM 1552 C CA  . ILE A 1 232 ? 79.021  86.758  -49.818 1.00 12.14  ? 232 ILE A1 CA  1 
ATOM 1553 C C   . ILE A 1 232 ? 78.335  85.709  -48.951 1.00 11.70  ? 232 ILE A1 C   1 
ATOM 1554 O O   . ILE A 1 232 ? 77.577  84.866  -49.438 1.00 12.23  ? 232 ILE A1 O   1 
ATOM 1555 C CB  . ILE A 1 232 ? 78.078  87.918  -50.202 1.00 11.56  ? 232 ILE A1 CB  1 
ATOM 1556 C CG1 . ILE A 1 232 ? 77.384  88.509  -48.973 1.00 14.12  ? 232 ILE A1 CG1 1 
ATOM 1557 C CG2 . ILE A 1 232 ? 77.080  87.501  -51.262 1.00 10.33  ? 232 ILE A1 CG2 1 
ATOM 1558 C CD1 . ILE A 1 232 ? 78.333  89.177  -48.001 1.00 16.90  ? 232 ILE A1 CD1 1 
ATOM 1559 N N   . TYR A 1 233 ? 78.652  85.732  -47.659 1.00 11.31  ? 233 TYR A1 N   1 
ATOM 1560 C CA  . TYR A 1 233 ? 77.878  85.036  -46.639 1.00 11.44  ? 233 TYR A1 CA  1 
ATOM 1561 C C   . TYR A 1 233 ? 76.840  86.018  -46.114 1.00 11.39  ? 233 TYR A1 C   1 
ATOM 1562 O O   . TYR A 1 233 ? 77.193  87.012  -45.474 1.00 11.60  ? 233 TYR A1 O   1 
ATOM 1563 C CB  . TYR A 1 233 ? 78.788  84.540  -45.519 1.00 11.97  ? 233 TYR A1 CB  1 
ATOM 1564 C CG  . TYR A 1 233 ? 78.062  84.038  -44.293 1.00 12.79  ? 233 TYR A1 CG  1 
ATOM 1565 C CD1 . TYR A 1 233 ? 77.933  84.828  -43.157 1.00 11.88  ? 233 TYR A1 CD1 1 
ATOM 1566 C CD2 . TYR A 1 233 ? 77.531  82.762  -44.264 1.00 15.03  ? 233 TYR A1 CD2 1 
ATOM 1567 C CE1 . TYR A 1 233 ? 77.269  84.366  -42.041 1.00 13.21  ? 233 TYR A1 CE1 1 
ATOM 1568 C CE2 . TYR A 1 233 ? 76.875  82.291  -43.152 1.00 15.66  ? 233 TYR A1 CE2 1 
ATOM 1569 C CZ  . TYR A 1 233 ? 76.744  83.096  -42.049 1.00 15.05  ? 233 TYR A1 CZ  1 
ATOM 1570 O OH  . TYR A 1 233 ? 76.087  82.620  -40.943 1.00 16.05  ? 233 TYR A1 OH  1 
ATOM 1571 N N   . HIS A 1 234 ? 75.564  85.755  -46.387 1.00 12.32  ? 234 HIS A1 N   1 
ATOM 1572 C CA  . HIS A 1 234 ? 74.529  86.717  -46.031 1.00 13.52  ? 234 HIS A1 CA  1 
ATOM 1573 C C   . HIS A 1 234 ? 74.272  86.717  -44.535 1.00 14.97  ? 234 HIS A1 C   1 
ATOM 1574 O O   . HIS A 1 234 ? 74.496  87.718  -43.846 1.00 17.15  ? 234 HIS A1 O   1 
ATOM 1575 C CB  . HIS A 1 234 ? 73.239  86.406  -46.782 1.00 15.12  ? 234 HIS A1 CB  1 
ATOM 1576 C CG  . HIS A 1 234 ? 73.379  86.448  -48.268 1.00 18.19  ? 234 HIS A1 CG  1 
ATOM 1577 N ND1 . HIS A 1 234 ? 72.767  85.533  -49.094 1.00 18.70  ? 234 HIS A1 ND1 1 
ATOM 1578 C CD2 . HIS A 1 234 ? 74.051  87.296  -49.078 1.00 20.12  ? 234 HIS A1 CD2 1 
ATOM 1579 C CE1 . HIS A 1 234 ? 73.057  85.816  -50.349 1.00 19.44  ? 234 HIS A1 CE1 1 
ATOM 1580 N NE2 . HIS A 1 234 ? 73.837  86.878  -50.367 1.00 20.53  ? 234 HIS A1 NE2 1 
ATOM 1581 N N   . GLY A 1 235 ? 73.811  85.595  -44.014 1.00 14.81  ? 235 GLY A1 N   1 
ATOM 1582 C CA  . GLY A 1 235 ? 73.460  85.490  -42.621 1.00 13.39  ? 235 GLY A1 CA  1 
ATOM 1583 C C   . GLY A 1 235 ? 72.514  84.329  -42.456 1.00 13.78  ? 235 GLY A1 C   1 
ATOM 1584 O O   . GLY A 1 235 ? 72.651  83.323  -43.148 1.00 15.04  ? 235 GLY A1 O   1 
ATOM 1585 N N   . THR A 1 236 ? 71.536  84.468  -41.576 1.00 12.94  ? 236 THR A1 N   1 
ATOM 1586 C CA  . THR A 1 236 ? 70.594  83.404  -41.281 1.00 11.97  ? 236 THR A1 CA  1 
ATOM 1587 C C   . THR A 1 236 ? 69.193  83.899  -41.589 1.00 11.86  ? 236 THR A1 C   1 
ATOM 1588 O O   . THR A 1 236 ? 68.800  84.972  -41.125 1.00 11.59  ? 236 THR A1 O   1 
ATOM 1589 C CB  . THR A 1 236 ? 70.704  82.984  -39.818 1.00 11.28  ? 236 THR A1 CB  1 
ATOM 1590 O OG1 . THR A 1 236 ? 72.037  82.538  -39.552 1.00 11.41  ? 236 THR A1 OG1 1 
ATOM 1591 C CG2 . THR A 1 236 ? 69.743  81.864  -39.520 1.00 11.53  ? 236 THR A1 CG2 1 
ATOM 1592 N N   . ASP A 1 237 ? 68.456  83.137  -42.379 1.00 11.26  ? 237 ASP A1 N   1 
ATOM 1593 C CA  . ASP A 1 237 ? 67.085  83.504  -42.703 1.00 9.44   ? 237 ASP A1 CA  1 
ATOM 1594 C C   . ASP A 1 237 ? 66.188  83.267  -41.496 1.00 6.34   ? 237 ASP A1 C   1 
ATOM 1595 O O   . ASP A 1 237 ? 66.084  82.133  -41.029 1.00 4.21   ? 237 ASP A1 O   1 
ATOM 1596 C CB  . ASP A 1 237 ? 66.580  82.695  -43.884 1.00 14.96  ? 237 ASP A1 CB  1 
ATOM 1597 C CG  . ASP A 1 237 ? 65.335  83.276  -44.491 1.00 22.49  ? 237 ASP A1 CG  1 
ATOM 1598 O OD1 . ASP A 1 237 ? 65.436  84.294  -45.204 1.00 26.22  ? 237 ASP A1 OD1 1 
ATOM 1599 O OD2 . ASP A 1 237 ? 64.250  82.715  -44.262 1.00 22.96  ? 237 ASP A1 OD2 1 
ATOM 1600 N N   . PRO A 1 238 ? 65.506  84.293  -40.982 1.00 4.84   ? 238 PRO A1 N   1 
ATOM 1601 C CA  . PRO A 1 238 ? 64.735  84.112  -39.745 1.00 5.04   ? 238 PRO A1 CA  1 
ATOM 1602 C C   . PRO A 1 238 ? 63.359  83.502  -39.944 1.00 5.83   ? 238 PRO A1 C   1 
ATOM 1603 O O   . PRO A 1 238 ? 62.386  83.942  -39.330 1.00 8.56   ? 238 PRO A1 O   1 
ATOM 1604 C CB  . PRO A 1 238 ? 64.620  85.540  -39.213 1.00 3.72   ? 238 PRO A1 CB  1 
ATOM 1605 C CG  . PRO A 1 238 ? 64.594  86.360  -40.433 1.00 3.98   ? 238 PRO A1 CG  1 
ATOM 1606 C CD  . PRO A 1 238 ? 65.529  85.700  -41.404 1.00 4.13   ? 238 PRO A1 CD  1 
ATOM 1607 N N   . ASP A 1 239 ? 63.272  82.487  -40.794 1.00 6.31   ? 239 ASP A1 N   1 
ATOM 1608 C CA  . ASP A 1 239 ? 62.144  81.576  -40.843 1.00 7.90   ? 239 ASP A1 CA  1 
ATOM 1609 C C   . ASP A 1 239 ? 62.602  80.147  -40.681 1.00 7.19   ? 239 ASP A1 C   1 
ATOM 1610 O O   . ASP A 1 239 ? 61.831  79.322  -40.185 1.00 10.26  ? 239 ASP A1 O   1 
ATOM 1611 C CB  . ASP A 1 239 ? 61.384  81.700  -42.169 1.00 12.49  ? 239 ASP A1 CB  1 
ATOM 1612 C CG  . ASP A 1 239 ? 61.127  83.134  -42.562 1.00 19.10  ? 239 ASP A1 CG  1 
ATOM 1613 O OD1 . ASP A 1 239 ? 60.501  83.867  -41.769 1.00 19.70  ? 239 ASP A1 OD1 1 
ATOM 1614 O OD2 . ASP A 1 239 ? 61.553  83.536  -43.666 1.00 23.68  ? 239 ASP A1 OD2 1 
ATOM 1615 N N   . ASP A 1 240 ? 63.838  79.838  -41.058 1.00 4.52   ? 240 ASP A1 N   1 
ATOM 1616 C CA  . ASP A 1 240 ? 64.399  78.508  -40.932 1.00 3.54   ? 240 ASP A1 CA  1 
ATOM 1617 C C   . ASP A 1 240 ? 65.355  78.407  -39.753 1.00 4.75   ? 240 ASP A1 C   1 
ATOM 1618 O O   . ASP A 1 240 ? 66.279  77.592  -39.786 1.00 7.71   ? 240 ASP A1 O   1 
ATOM 1619 C CB  . ASP A 1 240 ? 65.103  78.128  -42.234 1.00 4.36   ? 240 ASP A1 CB  1 
ATOM 1620 C CG  . ASP A 1 240 ? 64.298  78.515  -43.462 1.00 8.71   ? 240 ASP A1 CG  1 
ATOM 1621 O OD1 . ASP A 1 240 ? 63.079  78.255  -43.482 1.00 12.32  ? 240 ASP A1 OD1 1 
ATOM 1622 O OD2 . ASP A 1 240 ? 64.869  79.092  -44.409 1.00 3.73   ? 240 ASP A1 OD2 1 
ATOM 1623 N N   . VAL A 1 241 ? 65.169  79.225  -38.723 1.00 5.00   ? 241 VAL A1 N   1 
ATOM 1624 C CA  . VAL A 1 241 ? 65.981  79.156  -37.514 1.00 6.26   ? 241 VAL A1 CA  1 
ATOM 1625 C C   . VAL A 1 241 ? 65.460  78.013  -36.658 1.00 8.08   ? 241 VAL A1 C   1 
ATOM 1626 O O   . VAL A 1 241 ? 64.276  77.976  -36.313 1.00 9.69   ? 241 VAL A1 O   1 
ATOM 1627 C CB  . VAL A 1 241 ? 65.941  80.482  -36.745 1.00 5.23   ? 241 VAL A1 CB  1 
ATOM 1628 C CG1 . VAL A 1 241 ? 66.558  80.328  -35.380 1.00 2.40   ? 241 VAL A1 CG1 1 
ATOM 1629 C CG2 . VAL A 1 241 ? 66.660  81.548  -37.514 1.00 6.45   ? 241 VAL A1 CG2 1 
ATOM 1630 N N   . GLN A 1 242 ? 66.338  77.072  -36.324 1.00 9.07   ? 242 GLN A1 N   1 
ATOM 1631 C CA  . GLN A 1 242 ? 65.990  75.934  -35.485 1.00 7.26   ? 242 GLN A1 CA  1 
ATOM 1632 C C   . GLN A 1 242 ? 67.139  75.661  -34.534 1.00 7.74   ? 242 GLN A1 C   1 
ATOM 1633 O O   . GLN A 1 242 ? 68.176  75.142  -34.952 1.00 8.34   ? 242 GLN A1 O   1 
ATOM 1634 C CB  . GLN A 1 242 ? 65.698  74.699  -36.329 1.00 3.98   ? 242 GLN A1 CB  1 
ATOM 1635 C CG  . GLN A 1 242 ? 64.365  74.713  -37.030 1.00 4.48   ? 242 GLN A1 CG  1 
ATOM 1636 C CD  . GLN A 1 242 ? 64.066  73.395  -37.690 1.00 5.82   ? 242 GLN A1 CD  1 
ATOM 1637 O OE1 . GLN A 1 242 ? 64.513  73.131  -38.799 1.00 7.30   ? 242 GLN A1 OE1 1 
ATOM 1638 N NE2 . GLN A 1 242 ? 63.318  72.551  -37.003 1.00 6.61   ? 242 GLN A1 NE2 1 
ATOM 1639 N N   . PHE A 1 243 ? 66.956  76.001  -33.265 1.00 7.62   ? 243 PHE A1 N   1 
ATOM 1640 C CA  . PHE A 1 243 ? 67.964  75.802  -32.230 1.00 7.57   ? 243 PHE A1 CA  1 
ATOM 1641 C C   . PHE A 1 243 ? 67.457  74.696  -31.314 1.00 8.09   ? 243 PHE A1 C   1 
ATOM 1642 O O   . PHE A 1 243 ? 66.558  74.918  -30.500 1.00 7.28   ? 243 PHE A1 O   1 
ATOM 1643 C CB  . PHE A 1 243 ? 68.233  77.105  -31.481 1.00 5.20   ? 243 PHE A1 CB  1 
ATOM 1644 C CG  . PHE A 1 243 ? 68.983  76.937  -30.191 1.00 3.82   ? 243 PHE A1 CG  1 
ATOM 1645 C CD1 . PHE A 1 243 ? 70.157  76.215  -30.130 1.00 4.13   ? 243 PHE A1 CD1 1 
ATOM 1646 C CD2 . PHE A 1 243 ? 68.525  77.537  -29.039 1.00 3.55   ? 243 PHE A1 CD2 1 
ATOM 1647 C CE1 . PHE A 1 243 ? 70.826  76.064  -28.951 1.00 3.87   ? 243 PHE A1 CE1 1 
ATOM 1648 C CE2 . PHE A 1 243 ? 69.206  77.394  -27.856 1.00 3.09   ? 243 PHE A1 CE2 1 
ATOM 1649 C CZ  . PHE A 1 243 ? 70.353  76.657  -27.817 1.00 2.70   ? 243 PHE A1 CZ  1 
ATOM 1650 N N   . TYR A 1 244 ? 68.041  73.512  -31.444 1.00 8.50   ? 244 TYR A1 N   1 
ATOM 1651 C CA  . TYR A 1 244 ? 67.643  72.359  -30.657 1.00 8.84   ? 244 TYR A1 CA  1 
ATOM 1652 C C   . TYR A 1 244 ? 68.504  72.241  -29.415 1.00 8.76   ? 244 TYR A1 C   1 
ATOM 1653 O O   . TYR A 1 244 ? 69.711  72.483  -29.454 1.00 10.59  ? 244 TYR A1 O   1 
ATOM 1654 C CB  . TYR A 1 244 ? 67.768  71.075  -31.468 1.00 9.14   ? 244 TYR A1 CB  1 
ATOM 1655 C CG  . TYR A 1 244 ? 66.757  70.952  -32.559 1.00 10.94  ? 244 TYR A1 CG  1 
ATOM 1656 C CD1 . TYR A 1 244 ? 65.436  70.685  -32.265 1.00 11.74  ? 244 TYR A1 CD1 1 
ATOM 1657 C CD2 . TYR A 1 244 ? 67.121  71.097  -33.883 1.00 11.48  ? 244 TYR A1 CD2 1 
ATOM 1658 C CE1 . TYR A 1 244 ? 64.507  70.569  -33.254 1.00 11.97  ? 244 TYR A1 CE1 1 
ATOM 1659 C CE2 . TYR A 1 244 ? 66.200  70.985  -34.883 1.00 12.14  ? 244 TYR A1 CE2 1 
ATOM 1660 C CZ  . TYR A 1 244 ? 64.890  70.722  -34.559 1.00 12.56  ? 244 TYR A1 CZ  1 
ATOM 1661 O OH  . TYR A 1 244 ? 63.946  70.602  -35.547 1.00 16.35  ? 244 TYR A1 OH  1 
ATOM 1662 N N   . THR A 1 245 ? 67.875  71.857  -28.319 1.00 7.49   ? 245 THR A1 N   1 
ATOM 1663 C CA  . THR A 1 245 ? 68.556  71.570  -27.074 1.00 7.49   ? 245 THR A1 CA  1 
ATOM 1664 C C   . THR A 1 245 ? 68.197  70.153  -26.651 1.00 7.56   ? 245 THR A1 C   1 
ATOM 1665 O O   . THR A 1 245 ? 67.053  69.722  -26.797 1.00 7.63   ? 245 THR A1 O   1 
ATOM 1666 C CB  . THR A 1 245 ? 68.156  72.583  -25.998 1.00 6.38   ? 245 THR A1 CB  1 
ATOM 1667 O OG1 . THR A 1 245 ? 68.169  73.894  -26.556 1.00 5.82   ? 245 THR A1 OG1 1 
ATOM 1668 C CG2 . THR A 1 245 ? 69.111  72.566  -24.861 1.00 6.26   ? 245 THR A1 CG2 1 
ATOM 1669 N N   . ILE A 1 246 ? 69.191  69.419  -26.152 1.00 7.69   ? 246 ILE A1 N   1 
ATOM 1670 C CA  . ILE A 1 246 ? 68.950  68.066  -25.663 1.00 7.97   ? 246 ILE A1 CA  1 
ATOM 1671 C C   . ILE A 1 246 ? 68.140  68.108  -24.376 1.00 7.68   ? 246 ILE A1 C   1 
ATOM 1672 O O   . ILE A 1 246 ? 67.331  67.215  -24.103 1.00 8.68   ? 246 ILE A1 O   1 
ATOM 1673 C CB  . ILE A 1 246 ? 70.294  67.337  -25.473 1.00 8.63   ? 246 ILE A1 CB  1 
ATOM 1674 C CG1 . ILE A 1 246 ? 71.095  67.331  -26.773 1.00 8.73   ? 246 ILE A1 CG1 1 
ATOM 1675 C CG2 . ILE A 1 246 ? 70.114  65.911  -24.969 1.00 7.67   ? 246 ILE A1 CG2 1 
ATOM 1676 C CD1 . ILE A 1 246 ? 70.635  66.321  -27.771 1.00 10.74  ? 246 ILE A1 CD1 1 
ATOM 1677 N N   . GLU A 1 247 ? 68.311  69.170  -23.588 1.00 6.48   ? 247 GLU A1 N   1 
ATOM 1678 C CA  . GLU A 1 247 ? 67.623  69.286  -22.307 1.00 6.67   ? 247 GLU A1 CA  1 
ATOM 1679 C C   . GLU A 1 247 ? 66.121  69.469  -22.466 1.00 7.12   ? 247 GLU A1 C   1 
ATOM 1680 O O   . GLU A 1 247 ? 65.347  68.862  -21.723 1.00 7.02   ? 247 GLU A1 O   1 
ATOM 1681 C CB  . GLU A 1 247 ? 68.203  70.448  -21.515 1.00 6.56   ? 247 GLU A1 CB  1 
ATOM 1682 C CG  . GLU A 1 247 ? 69.409  70.072  -20.700 1.00 7.01   ? 247 GLU A1 CG  1 
ATOM 1683 C CD  . GLU A 1 247 ? 70.695  70.260  -21.456 1.00 7.84   ? 247 GLU A1 CD  1 
ATOM 1684 O OE1 . GLU A 1 247 ? 70.640  70.747  -22.598 1.00 9.67   ? 247 GLU A1 OE1 1 
ATOM 1685 O OE2 . GLU A 1 247 ? 71.764  69.923  -20.909 1.00 8.48   ? 247 GLU A1 OE2 1 
ATOM 1686 N N   . ASN A 1 248 ? 65.693  70.272  -23.426 1.00 7.26   ? 248 ASN A1 N   1 
ATOM 1687 C CA  . ASN A 1 248 ? 64.284  70.584  -23.590 1.00 6.43   ? 248 ASN A1 CA  1 
ATOM 1688 C C   . ASN A 1 248 ? 63.532  69.554  -24.411 1.00 6.83   ? 248 ASN A1 C   1 
ATOM 1689 O O   . ASN A 1 248 ? 62.312  69.675  -24.554 1.00 8.28   ? 248 ASN A1 O   1 
ATOM 1690 C CB  . ASN A 1 248 ? 64.129  71.953  -24.244 1.00 8.00   ? 248 ASN A1 CB  1 
ATOM 1691 C CG  . ASN A 1 248 ? 64.852  73.024  -23.494 1.00 10.31  ? 248 ASN A1 CG  1 
ATOM 1692 O OD1 . ASN A 1 248 ? 66.069  72.985  -23.369 1.00 11.49  ? 248 ASN A1 OD1 1 
ATOM 1693 N ND2 . ASN A 1 248 ? 64.115  73.996  -22.994 1.00 12.73  ? 248 ASN A1 ND2 1 
ATOM 1694 N N   . SER A 1 249 ? 64.212  68.557  -24.960 1.00 7.23   ? 249 SER A1 N   1 
ATOM 1695 C CA  . SER A 1 249 ? 63.548  67.655  -25.886 1.00 8.39   ? 249 SER A1 CA  1 
ATOM 1696 C C   . SER A 1 249 ? 63.601  66.207  -25.431 1.00 8.27   ? 249 SER A1 C   1 
ATOM 1697 O O   . SER A 1 249 ? 62.679  65.433  -25.702 1.00 11.97  ? 249 SER A1 O   1 
ATOM 1698 C CB  . SER A 1 249 ? 64.176  67.776  -27.264 1.00 9.71   ? 249 SER A1 CB  1 
ATOM 1699 O OG  . SER A 1 249 ? 64.121  69.109  -27.741 1.00 11.83  ? 249 SER A1 OG  1 
ATOM 1700 N N   . VAL A 1 250 ? 64.677  65.826  -24.756 1.00 7.52   ? 250 VAL A1 N   1 
ATOM 1701 C CA  . VAL A 1 250 ? 64.906  64.433  -24.392 1.00 5.09   ? 250 VAL A1 CA  1 
ATOM 1702 C C   . VAL A 1 250 ? 64.868  64.306  -22.873 1.00 5.45   ? 250 VAL A1 C   1 
ATOM 1703 O O   . VAL A 1 250 ? 65.331  65.215  -22.171 1.00 5.29   ? 250 VAL A1 O   1 
ATOM 1704 C CB  . VAL A 1 250 ? 66.246  63.933  -24.953 1.00 4.88   ? 250 VAL A1 CB  1 
ATOM 1705 C CG1 . VAL A 1 250 ? 66.283  62.438  -24.963 1.00 3.34   ? 250 VAL A1 CG1 1 
ATOM 1706 C CG2 . VAL A 1 250 ? 66.478  64.453  -26.349 1.00 6.06   ? 250 VAL A1 CG2 1 
ATOM 1707 N N   . PRO A 1 251 ? 64.299  63.237  -22.317 1.00 5.71   ? 251 PRO A1 N   1 
ATOM 1708 C CA  . PRO A 1 251 ? 64.517  62.953  -20.894 1.00 6.73   ? 251 PRO A1 CA  1 
ATOM 1709 C C   . PRO A 1 251 ? 65.895  62.348  -20.679 1.00 7.27   ? 251 PRO A1 C   1 
ATOM 1710 O O   . PRO A 1 251 ? 66.245  61.334  -21.285 1.00 8.96   ? 251 PRO A1 O   1 
ATOM 1711 C CB  . PRO A 1 251 ? 63.403  61.960  -20.551 1.00 4.69   ? 251 PRO A1 CB  1 
ATOM 1712 C CG  . PRO A 1 251 ? 62.431  62.061  -21.665 1.00 4.99   ? 251 PRO A1 CG  1 
ATOM 1713 C CD  . PRO A 1 251 ? 63.234  62.393  -22.873 1.00 4.99   ? 251 PRO A1 CD  1 
ATOM 1714 N N   . VAL A 1 252 ? 66.668  62.968  -19.800 1.00 7.58   ? 252 VAL A1 N   1 
ATOM 1715 C CA  . VAL A 1 252 ? 68.060  62.619  -19.566 1.00 6.91   ? 252 VAL A1 CA  1 
ATOM 1716 C C   . VAL A 1 252 ? 68.145  61.755  -18.318 1.00 8.26   ? 252 VAL A1 C   1 
ATOM 1717 O O   . VAL A 1 252 ? 67.581  62.103  -17.278 1.00 8.19   ? 252 VAL A1 O   1 
ATOM 1718 C CB  . VAL A 1 252 ? 68.915  63.888  -19.421 1.00 4.00   ? 252 VAL A1 CB  1 
ATOM 1719 C CG1 . VAL A 1 252 ? 70.302  63.556  -18.959 1.00 2.96   ? 252 VAL A1 CG1 1 
ATOM 1720 C CG2 . VAL A 1 252 ? 68.958  64.636  -20.727 1.00 3.84   ? 252 VAL A1 CG2 1 
ATOM 1721 N N   . HIS A 1 253 ? 68.833  60.623  -18.419 1.00 8.50   ? 253 HIS A1 N   1 
ATOM 1722 C CA  . HIS A 1 253 ? 69.093  59.773  -17.269 1.00 9.68   ? 253 HIS A1 CA  1 
ATOM 1723 C C   . HIS A 1 253 ? 70.485  60.044  -16.723 1.00 10.62  ? 253 HIS A1 C   1 
ATOM 1724 O O   . HIS A 1 253 ? 71.460  60.066  -17.472 1.00 12.92  ? 253 HIS A1 O   1 
ATOM 1725 C CB  . HIS A 1 253 ? 68.969  58.300  -17.648 1.00 10.60  ? 253 HIS A1 CB  1 
ATOM 1726 C CG  . HIS A 1 253 ? 67.658  57.945  -18.272 1.00 13.34  ? 253 HIS A1 CG  1 
ATOM 1727 N ND1 . HIS A 1 253 ? 67.419  58.073  -19.621 1.00 15.15  ? 253 HIS A1 ND1 1 
ATOM 1728 C CD2 . HIS A 1 253 ? 66.511  57.480  -17.728 1.00 13.96  ? 253 HIS A1 CD2 1 
ATOM 1729 C CE1 . HIS A 1 253 ? 66.181  57.698  -19.883 1.00 15.04  ? 253 HIS A1 CE1 1 
ATOM 1730 N NE2 . HIS A 1 253 ? 65.608  57.333  -18.751 1.00 15.19  ? 253 HIS A1 NE2 1 
ATOM 1731 N N   . LEU A 1 254 ? 70.580  60.230  -15.412 1.00 10.68  ? 254 LEU A1 N   1 
ATOM 1732 C CA  . LEU A 1 254 ? 71.856  60.476  -14.757 1.00 9.25   ? 254 LEU A1 CA  1 
ATOM 1733 C C   . LEU A 1 254 ? 72.376  59.167  -14.184 1.00 8.15   ? 254 LEU A1 C   1 
ATOM 1734 O O   . LEU A 1 254 ? 71.933  58.738  -13.115 1.00 9.49   ? 254 LEU A1 O   1 
ATOM 1735 C CB  . LEU A 1 254 ? 71.717  61.516  -13.647 1.00 8.61   ? 254 LEU A1 CB  1 
ATOM 1736 C CG  . LEU A 1 254 ? 70.838  62.737  -13.890 1.00 8.35   ? 254 LEU A1 CG  1 
ATOM 1737 C CD1 . LEU A 1 254 ? 70.405  63.310  -12.576 1.00 9.66   ? 254 LEU A1 CD1 1 
ATOM 1738 C CD2 . LEU A 1 254 ? 71.578  63.770  -14.680 1.00 9.82   ? 254 LEU A1 CD2 1 
ATOM 1739 N N   . LEU A 1 255 ? 73.322  58.544  -14.880 1.00 6.30   ? 255 LEU A1 N   1 
ATOM 1740 C CA  . LEU A 1 255 ? 73.895  57.270  -14.467 1.00 5.14   ? 255 LEU A1 CA  1 
ATOM 1741 C C   . LEU A 1 255 ? 75.037  57.529  -13.501 1.00 5.49   ? 255 LEU A1 C   1 
ATOM 1742 O O   . LEU A 1 255 ? 75.990  58.234  -13.842 1.00 6.23   ? 255 LEU A1 O   1 
ATOM 1743 C CB  . LEU A 1 255 ? 74.410  56.476  -15.663 1.00 3.51   ? 255 LEU A1 CB  1 
ATOM 1744 C CG  . LEU A 1 255 ? 73.456  56.046  -16.762 1.00 2.60   ? 255 LEU A1 CG  1 
ATOM 1745 C CD1 . LEU A 1 255 ? 74.113  54.958  -17.552 1.00 2.18   ? 255 LEU A1 CD1 1 
ATOM 1746 C CD2 . LEU A 1 255 ? 72.143  55.579  -16.199 1.00 2.75   ? 255 LEU A1 CD2 1 
ATOM 1747 N N   . ARG A 1 256 ? 74.949  56.956  -12.313 1.00 5.69   ? 256 ARG A1 N   1 
ATOM 1748 C CA  . ARG A 1 256 ? 76.064  56.941  -11.384 1.00 6.33   ? 256 ARG A1 CA  1 
ATOM 1749 C C   . ARG A 1 256 ? 76.895  55.690  -11.649 1.00 6.85   ? 256 ARG A1 C   1 
ATOM 1750 O O   . ARG A 1 256 ? 76.769  55.057  -12.696 1.00 6.60   ? 256 ARG A1 O   1 
ATOM 1751 C CB  . ARG A 1 256 ? 75.561  57.031  -9.950  1.00 6.34   ? 256 ARG A1 CB  1 
ATOM 1752 C CG  . ARG A 1 256 ? 75.538  58.442  -9.431  1.00 4.70   ? 256 ARG A1 CG  1 
ATOM 1753 C CD  . ARG A 1 256 ? 74.774  58.546  -8.142  1.00 3.87   ? 256 ARG A1 CD  1 
ATOM 1754 N NE  . ARG A 1 256 ? 74.991  59.831  -7.497  1.00 5.50   ? 256 ARG A1 NE  1 
ATOM 1755 C CZ  . ARG A 1 256 ? 74.494  60.158  -6.316  1.00 6.72   ? 256 ARG A1 CZ  1 
ATOM 1756 N NH1 . ARG A 1 256 ? 73.751  59.294  -5.650  1.00 7.50   ? 256 ARG A1 NH1 1 
ATOM 1757 N NH2 . ARG A 1 256 ? 74.738  61.348  -5.800  1.00 6.63   ? 256 ARG A1 NH2 1 
ATOM 1758 N N   . THR A 1 257 ? 77.774  55.324  -10.713 1.00 8.81   ? 257 THR A1 N   1 
ATOM 1759 C CA  . THR A 1 257 ? 78.712  54.236  -10.973 1.00 9.78   ? 257 THR A1 CA  1 
ATOM 1760 C C   . THR A 1 257 ? 78.024  52.873  -10.979 1.00 9.10   ? 257 THR A1 C   1 
ATOM 1761 O O   . THR A 1 257 ? 78.360  52.008  -11.793 1.00 10.54  ? 257 THR A1 O   1 
ATOM 1762 C CB  . THR A 1 257 ? 79.885  54.289  -9.982  1.00 10.53  ? 257 THR A1 CB  1 
ATOM 1763 O OG1 . THR A 1 257 ? 80.832  53.265  -10.300 1.00 16.16  ? 257 THR A1 OG1 1 
ATOM 1764 C CG2 . THR A 1 257 ? 79.462  54.190  -8.514  1.00 11.62  ? 257 THR A1 CG2 1 
ATOM 1765 N N   . GLY A 1 258 ? 77.065  52.647  -10.089 1.00 6.96   ? 258 GLY A1 N   1 
ATOM 1766 C CA  . GLY A 1 258 ? 76.252  51.463  -10.243 1.00 5.36   ? 258 GLY A1 CA  1 
ATOM 1767 C C   . GLY A 1 258 ? 74.937  51.795  -10.898 1.00 4.55   ? 258 GLY A1 C   1 
ATOM 1768 O O   . GLY A 1 258 ? 73.956  52.055  -10.204 1.00 5.57   ? 258 GLY A1 O   1 
ATOM 1769 N N   . ASP A 1 259 ? 74.889  51.699  -12.224 1.00 5.04   ? 259 ASP A1 N   1 
ATOM 1770 C CA  . ASP A 1 259 ? 73.740  52.109  -13.018 1.00 6.66   ? 259 ASP A1 CA  1 
ATOM 1771 C C   . ASP A 1 259 ? 73.928  51.597  -14.433 1.00 9.20   ? 259 ASP A1 C   1 
ATOM 1772 O O   . ASP A 1 259 ? 75.046  51.522  -14.945 1.00 11.36  ? 259 ASP A1 O   1 
ATOM 1773 C CB  . ASP A 1 259 ? 73.554  53.627  -13.015 1.00 7.25   ? 259 ASP A1 CB  1 
ATOM 1774 C CG  . ASP A 1 259 ? 72.390  54.072  -12.157 1.00 9.48   ? 259 ASP A1 CG  1 
ATOM 1775 O OD1 . ASP A 1 259 ? 72.112  55.284  -12.115 1.00 11.58  ? 259 ASP A1 OD1 1 
ATOM 1776 O OD2 . ASP A 1 259 ? 71.724  53.212  -11.554 1.00 10.72  ? 259 ASP A1 OD2 1 
ATOM 1777 N N   . GLU A 1 260 ? 72.811  51.249  -15.057 1.00 11.74  ? 260 GLU A1 N   1 
ATOM 1778 C CA  . GLU A 1 260 ? 72.825  50.611  -16.368 1.00 13.88  ? 260 GLU A1 CA  1 
ATOM 1779 C C   . GLU A 1 260 ? 71.678  51.185  -17.175 1.00 12.23  ? 260 GLU A1 C   1 
ATOM 1780 O O   . GLU A 1 260 ? 70.523  51.085  -16.754 1.00 13.35  ? 260 GLU A1 O   1 
ATOM 1781 C CB  . GLU A 1 260 ? 72.685  49.100  -16.235 1.00 17.82  ? 260 GLU A1 CB  1 
ATOM 1782 C CG  . GLU A 1 260 ? 73.163  48.325  -17.441 1.00 25.65  ? 260 GLU A1 CG  1 
ATOM 1783 C CD  . GLU A 1 260 ? 72.034  47.774  -18.282 1.00 29.47  ? 260 GLU A1 CD  1 
ATOM 1784 O OE1 . GLU A 1 260 ? 70.872  47.833  -17.832 1.00 31.05  ? 260 GLU A1 OE1 1 
ATOM 1785 O OE2 . GLU A 1 260 ? 72.311  47.273  -19.390 1.00 31.35  ? 260 GLU A1 OE2 1 
ATOM 1786 N N   . PHE A 1 261 ? 71.980  51.788  -18.312 1.00 10.38  ? 261 PHE A1 N   1 
ATOM 1787 C CA  . PHE A 1 261 ? 70.955  52.318  -19.202 1.00 9.79   ? 261 PHE A1 CA  1 
ATOM 1788 C C   . PHE A 1 261 ? 70.862  51.413  -20.417 1.00 10.37  ? 261 PHE A1 C   1 
ATOM 1789 O O   . PHE A 1 261 ? 71.724  51.446  -21.294 1.00 10.69  ? 261 PHE A1 O   1 
ATOM 1790 C CB  . PHE A 1 261 ? 71.269  53.749  -19.606 1.00 9.00   ? 261 PHE A1 CB  1 
ATOM 1791 C CG  . PHE A 1 261 ? 70.291  54.327  -20.567 1.00 8.43   ? 261 PHE A1 CG  1 
ATOM 1792 C CD1 . PHE A 1 261 ? 70.653  54.582  -21.869 1.00 9.08   ? 261 PHE A1 CD1 1 
ATOM 1793 C CD2 . PHE A 1 261 ? 69.003  54.605  -20.172 1.00 8.02   ? 261 PHE A1 CD2 1 
ATOM 1794 C CE1 . PHE A 1 261 ? 69.750  55.117  -22.754 1.00 8.93   ? 261 PHE A1 CE1 1 
ATOM 1795 C CE2 . PHE A 1 261 ? 68.098  55.134  -21.058 1.00 7.09   ? 261 PHE A1 CE2 1 
ATOM 1796 C CZ  . PHE A 1 261 ? 68.474  55.389  -22.349 1.00 7.36   ? 261 PHE A1 CZ  1 
ATOM 1797 N N   . ALA A 1 262 ? 69.812  50.610  -20.474 1.00 10.83  ? 262 ALA A1 N   1 
ATOM 1798 C CA  . ALA A 1 262 ? 69.524  49.784  -21.632 1.00 10.87  ? 262 ALA A1 CA  1 
ATOM 1799 C C   . ALA A 1 262 ? 68.359  50.398  -22.382 1.00 11.08  ? 262 ALA A1 C   1 
ATOM 1800 O O   . ALA A 1 262 ? 67.321  50.691  -21.783 1.00 13.11  ? 262 ALA A1 O   1 
ATOM 1801 C CB  . ALA A 1 262 ? 69.197  48.352  -21.223 1.00 10.08  ? 262 ALA A1 CB  1 
ATOM 1802 N N   . THR A 1 263 ? 68.528  50.608  -23.680 1.00 12.62  ? 263 THR A1 N   1 
ATOM 1803 C CA  . THR A 1 263 ? 67.399  51.020  -24.492 1.00 12.68  ? 263 THR A1 CA  1 
ATOM 1804 C C   . THR A 1 263 ? 66.595  49.788  -24.898 1.00 14.73  ? 263 THR A1 C   1 
ATOM 1805 O O   . THR A 1 263 ? 66.959  48.648  -24.604 1.00 19.02  ? 263 THR A1 O   1 
ATOM 1806 C CB  . THR A 1 263 ? 67.859  51.764  -25.738 1.00 12.92  ? 263 THR A1 CB  1 
ATOM 1807 O OG1 . THR A 1 263 ? 68.396  50.829  -26.672 1.00 15.09  ? 263 THR A1 OG1 1 
ATOM 1808 C CG2 . THR A 1 263 ? 68.952  52.722  -25.379 1.00 11.19  ? 263 THR A1 CG2 1 
ATOM 1809 N N   . GLY A 1 264 ? 65.506  50.018  -25.608 1.00 13.75  ? 264 GLY A1 N   1 
ATOM 1810 C CA  . GLY A 1 264 ? 64.698  48.926  -26.099 1.00 13.34  ? 264 GLY A1 CA  1 
ATOM 1811 C C   . GLY A 1 264 ? 65.325  48.270  -27.310 1.00 13.37  ? 264 GLY A1 C   1 
ATOM 1812 O O   . GLY A 1 264 ? 66.487  48.501  -27.650 1.00 15.86  ? 264 GLY A1 O   1 
ATOM 1813 N N   . THR A 1 265 ? 64.543  47.435  -27.966 1.00 10.74  ? 265 THR A1 N   1 
ATOM 1814 C CA  . THR A 1 265 ? 64.937  46.856  -29.240 1.00 10.24  ? 265 THR A1 CA  1 
ATOM 1815 C C   . THR A 1 265 ? 64.128  47.534  -30.342 1.00 11.91  ? 265 THR A1 C   1 
ATOM 1816 O O   . THR A 1 265 ? 62.894  47.517  -30.331 1.00 14.08  ? 265 THR A1 O   1 
ATOM 1817 C CB  . THR A 1 265 ? 64.816  45.327  -29.213 1.00 9.11   ? 265 THR A1 CB  1 
ATOM 1818 O OG1 . THR A 1 265 ? 65.215  44.772  -30.470 1.00 10.61  ? 265 THR A1 OG1 1 
ATOM 1819 C CG2 . THR A 1 265 ? 63.454  44.810  -28.769 1.00 8.99   ? 265 THR A1 CG2 1 
ATOM 1820 N N   . PHE A 1 266 ? 64.824  48.220  -31.238 1.00 12.70  ? 266 PHE A1 N   1 
ATOM 1821 C CA  . PHE A 1 266 ? 64.149  48.893  -32.333 1.00 12.68  ? 266 PHE A1 CA  1 
ATOM 1822 C C   . PHE A 1 266 ? 64.021  47.969  -33.529 1.00 12.58  ? 266 PHE A1 C   1 
ATOM 1823 O O   . PHE A 1 266 ? 65.015  47.619  -34.158 1.00 11.59  ? 266 PHE A1 O   1 
ATOM 1824 C CB  . PHE A 1 266 ? 64.910  50.147  -32.747 1.00 14.40  ? 266 PHE A1 CB  1 
ATOM 1825 C CG  . PHE A 1 266 ? 64.175  50.975  -33.743 1.00 16.69  ? 266 PHE A1 CG  1 
ATOM 1826 C CD1 . PHE A 1 266 ? 64.451  50.877  -35.094 1.00 17.61  ? 266 PHE A1 CD1 1 
ATOM 1827 C CD2 . PHE A 1 266 ? 63.183  51.834  -33.328 1.00 17.73  ? 266 PHE A1 CD2 1 
ATOM 1828 C CE1 . PHE A 1 266 ? 63.754  51.618  -36.006 1.00 18.35  ? 266 PHE A1 CE1 1 
ATOM 1829 C CE2 . PHE A 1 266 ? 62.490  52.584  -34.232 1.00 17.19  ? 266 PHE A1 CE2 1 
ATOM 1830 C CZ  . PHE A 1 266 ? 62.778  52.475  -35.575 1.00 17.06  ? 266 PHE A1 CZ  1 
ATOM 1831 N N   . PHE A 1 267 ? 62.785  47.651  -33.900 1.00 13.65  ? 267 PHE A1 N   1 
ATOM 1832 C CA  . PHE A 1 267 ? 62.506  46.742  -35.002 1.00 14.47  ? 267 PHE A1 CA  1 
ATOM 1833 C C   . PHE A 1 267 ? 62.402  47.538  -36.289 1.00 17.39  ? 267 PHE A1 C   1 
ATOM 1834 O O   . PHE A 1 267 ? 61.540  48.412  -36.413 1.00 19.60  ? 267 PHE A1 O   1 
ATOM 1835 C CB  . PHE A 1 267 ? 61.217  45.968  -34.754 1.00 11.11  ? 267 PHE A1 CB  1 
ATOM 1836 C CG  . PHE A 1 267 ? 61.329  44.964  -33.668 1.00 9.22   ? 267 PHE A1 CG  1 
ATOM 1837 C CD1 . PHE A 1 267 ? 61.892  43.731  -33.910 1.00 9.25   ? 267 PHE A1 CD1 1 
ATOM 1838 C CD2 . PHE A 1 267 ? 60.889  45.261  -32.399 1.00 8.97   ? 267 PHE A1 CD2 1 
ATOM 1839 C CE1 . PHE A 1 267 ? 62.005  42.809  -32.910 1.00 8.50   ? 267 PHE A1 CE1 1 
ATOM 1840 C CE2 . PHE A 1 267 ? 61.000  44.343  -31.390 1.00 9.50   ? 267 PHE A1 CE2 1 
ATOM 1841 C CZ  . PHE A 1 267 ? 61.560  43.114  -31.645 1.00 9.01   ? 267 PHE A1 CZ  1 
ATOM 1842 N N   . PHE A 1 268 ? 63.266  47.226  -37.246 1.00 19.31  ? 268 PHE A1 N   1 
ATOM 1843 C CA  . PHE A 1 268 ? 63.312  47.934  -38.510 1.00 21.36  ? 268 PHE A1 CA  1 
ATOM 1844 C C   . PHE A 1 268 ? 62.194  47.476  -39.429 1.00 24.92  ? 268 PHE A1 C   1 
ATOM 1845 O O   . PHE A 1 268 ? 61.509  46.482  -39.181 1.00 25.66  ? 268 PHE A1 O   1 
ATOM 1846 C CB  . PHE A 1 268 ? 64.638  47.698  -39.227 1.00 19.10  ? 268 PHE A1 CB  1 
ATOM 1847 C CG  . PHE A 1 268 ? 65.829  48.227  -38.508 1.00 17.32  ? 268 PHE A1 CG  1 
ATOM 1848 C CD1 . PHE A 1 268 ? 66.477  47.467  -37.564 1.00 15.87  ? 268 PHE A1 CD1 1 
ATOM 1849 C CD2 . PHE A 1 268 ? 66.310  49.477  -38.789 1.00 16.95  ? 268 PHE A1 CD2 1 
ATOM 1850 C CE1 . PHE A 1 268 ? 67.576  47.953  -36.915 1.00 15.50  ? 268 PHE A1 CE1 1 
ATOM 1851 C CE2 . PHE A 1 268 ? 67.403  49.961  -38.140 1.00 15.66  ? 268 PHE A1 CE2 1 
ATOM 1852 C CZ  . PHE A 1 268 ? 68.035  49.196  -37.200 1.00 15.25  ? 268 PHE A1 CZ  1 
ATOM 1853 N N   . ASP A 1 269 ? 62.031  48.214  -40.519 1.00 28.63  ? 269 ASP A1 N   1 
ATOM 1854 C CA  . ASP A 1 269 ? 61.220  47.783  -41.650 1.00 31.59  ? 269 ASP A1 CA  1 
ATOM 1855 C C   . ASP A 1 269 ? 61.826  48.372  -42.915 1.00 31.73  ? 269 ASP A1 C   1 
ATOM 1856 O O   . ASP A 1 269 ? 61.587  49.531  -43.260 1.00 32.54  ? 269 ASP A1 O   1 
ATOM 1857 C CB  . ASP A 1 269 ? 59.749  48.168  -41.462 1.00 35.29  ? 269 ASP A1 CB  1 
ATOM 1858 C CG  . ASP A 1 269 ? 59.568  49.601  -41.028 1.00 38.00  ? 269 ASP A1 CG  1 
ATOM 1859 O OD1 . ASP A 1 269 ? 58.416  50.083  -41.048 1.00 38.94  ? 269 ASP A1 OD1 1 
ATOM 1860 O OD2 . ASP A 1 269 ? 60.582  50.238  -40.668 1.00 37.42  ? 269 ASP A1 OD2 1 
ATOM 1861 N N   . CYS A 1 270 ? 62.631  47.568  -43.597 1.00 30.57  ? 270 CYS A1 N   1 
ATOM 1862 C CA  . CYS A 1 270 ? 63.420  48.034  -44.719 1.00 29.62  ? 270 CYS A1 CA  1 
ATOM 1863 C C   . CYS A 1 270 ? 63.183  47.091  -45.889 1.00 30.14  ? 270 CYS A1 C   1 
ATOM 1864 O O   . CYS A 1 270 ? 62.461  46.098  -45.771 1.00 33.83  ? 270 CYS A1 O   1 
ATOM 1865 C CB  . CYS A 1 270 ? 64.903  48.103  -44.336 1.00 28.32  ? 270 CYS A1 CB  1 
ATOM 1866 S SG  . CYS A 1 270 ? 65.320  49.353  -43.112 1.00 25.71  ? 270 CYS A1 SG  1 
ATOM 1867 N N   . LYS A 1 271 ? 63.760  47.394  -46.972 1.00 27.41  ? 271 LYS A1 N   1 
ATOM 1868 C CA  . LYS A 1 271 ? 63.761  46.420  -48.044 1.00 23.78  ? 271 LYS A1 CA  1 
ATOM 1869 C C   . LYS A 1 271 ? 64.971  45.505  -47.906 1.00 19.78  ? 271 LYS A1 C   1 
ATOM 1870 O O   . LYS A 1 271 ? 65.974  45.888  -47.297 1.00 19.13  ? 271 LYS A1 O   1 
ATOM 1871 C CB  . LYS A 1 271 ? 63.793  47.120  -49.397 1.00 27.06  ? 271 LYS A1 CB  1 
ATOM 1872 C CG  . LYS A 1 271 ? 62.478  47.752  -49.791 1.00 33.12  ? 271 LYS A1 CG  1 
ATOM 1873 C CD  . LYS A 1 271 ? 62.623  48.547  -51.068 1.00 38.87  ? 271 LYS A1 CD  1 
ATOM 1874 C CE  . LYS A 1 271 ? 61.915  49.873  -50.949 1.00 42.36  ? 271 LYS A1 CE  1 
ATOM 1875 N NZ  . LYS A 1 271 ? 62.657  50.783  -50.040 1.00 45.31  ? 271 LYS A1 NZ  1 
ATOM 1876 N N   . PRO A 1 272 ? 64.901  44.280  -48.421 1.00 16.27  ? 272 PRO A1 N   1 
ATOM 1877 C CA  . PRO A 1 272 ? 66.071  43.402  -48.380 1.00 15.30  ? 272 PRO A1 CA  1 
ATOM 1878 C C   . PRO A 1 272 ? 67.194  43.900  -49.273 1.00 14.65  ? 272 PRO A1 C   1 
ATOM 1879 O O   . PRO A 1 272 ? 66.969  44.443  -50.355 1.00 16.76  ? 272 PRO A1 O   1 
ATOM 1880 C CB  . PRO A 1 272 ? 65.524  42.065  -48.883 1.00 15.01  ? 272 PRO A1 CB  1 
ATOM 1881 C CG  . PRO A 1 272 ? 64.096  42.120  -48.577 1.00 16.34  ? 272 PRO A1 CG  1 
ATOM 1882 C CD  . PRO A 1 272 ? 63.687  43.535  -48.782 1.00 16.41  ? 272 PRO A1 CD  1 
ATOM 1883 N N   . CYS A 1 273 ? 68.416  43.711  -48.795 1.00 13.00  ? 273 CYS A1 N   1 
ATOM 1884 C CA  . CYS A 1 273 ? 69.618  44.052  -49.540 1.00 10.93  ? 273 CYS A1 CA  1 
ATOM 1885 C C   . CYS A 1 273 ? 70.147  42.828  -50.267 1.00 10.30  ? 273 CYS A1 C   1 
ATOM 1886 O O   . CYS A 1 273 ? 70.431  41.809  -49.638 1.00 10.64  ? 273 CYS A1 O   1 
ATOM 1887 C CB  . CYS A 1 273 ? 70.701  44.595  -48.615 1.00 11.15  ? 273 CYS A1 CB  1 
ATOM 1888 S SG  . CYS A 1 273 ? 72.027  45.402  -49.495 1.00 12.69  ? 273 CYS A1 SG  1 
ATOM 1889 N N   . ARG A 1 274 ? 70.314  42.944  -51.577 1.00 9.68   ? 274 ARG A1 N   1 
ATOM 1890 C CA  . ARG A 1 274 ? 70.834  41.855  -52.386 1.00 9.35   ? 274 ARG A1 CA  1 
ATOM 1891 C C   . ARG A 1 274 ? 72.347  41.784  -52.267 1.00 8.56   ? 274 ARG A1 C   1 
ATOM 1892 O O   . ARG A 1 274 ? 73.041  42.782  -52.472 1.00 8.68   ? 274 ARG A1 O   1 
ATOM 1893 C CB  . ARG A 1 274 ? 70.442  42.039  -53.845 1.00 11.17  ? 274 ARG A1 CB  1 
ATOM 1894 C CG  . ARG A 1 274 ? 69.007  42.404  -54.032 1.00 16.14  ? 274 ARG A1 CG  1 
ATOM 1895 C CD  . ARG A 1 274 ? 68.108  41.259  -53.647 1.00 21.12  ? 274 ARG A1 CD  1 
ATOM 1896 N NE  . ARG A 1 274 ? 68.049  40.233  -54.678 1.00 25.26  ? 274 ARG A1 NE  1 
ATOM 1897 C CZ  . ARG A 1 274 ? 67.257  40.293  -55.741 1.00 28.31  ? 274 ARG A1 CZ  1 
ATOM 1898 N NH1 . ARG A 1 274 ? 66.458  41.335  -55.922 1.00 25.57  ? 274 ARG A1 NH1 1 
ATOM 1899 N NH2 . ARG A 1 274 ? 67.263  39.310  -56.627 1.00 31.19  ? 274 ARG A1 NH2 1 
ATOM 1900 N N   . LEU A 1 275 ? 72.854  40.600  -51.933 1.00 6.68   ? 275 LEU A1 N   1 
ATOM 1901 C CA  . LEU A 1 275 ? 74.283  40.338  -51.913 1.00 4.63   ? 275 LEU A1 CA  1 
ATOM 1902 C C   . LEU A 1 275 ? 74.762  39.695  -53.201 1.00 4.17   ? 275 LEU A1 C   1 
ATOM 1903 O O   . LEU A 1 275 ? 75.789  39.013  -53.200 1.00 6.61   ? 275 LEU A1 O   1 
ATOM 1904 C CB  . LEU A 1 275 ? 74.640  39.457  -50.723 1.00 3.00   ? 275 LEU A1 CB  1 
ATOM 1905 C CG  . LEU A 1 275 ? 74.395  40.070  -49.355 1.00 2.18   ? 275 LEU A1 CG  1 
ATOM 1906 C CD1 . LEU A 1 275 ? 74.582  39.017  -48.315 1.00 2.00   ? 275 LEU A1 CD1 1 
ATOM 1907 C CD2 . LEU A 1 275 ? 75.342  41.211  -49.123 1.00 2.00   ? 275 LEU A1 CD2 1 
ATOM 1908 N N   . THR A 1 276 ? 74.022  39.875  -54.291 1.00 4.10   ? 276 THR A1 N   1 
ATOM 1909 C CA  . THR A 1 276 ? 74.399  39.390  -55.612 1.00 5.87   ? 276 THR A1 CA  1 
ATOM 1910 C C   . THR A 1 276 ? 74.310  40.561  -56.576 1.00 6.38   ? 276 THR A1 C   1 
ATOM 1911 O O   . THR A 1 276 ? 73.446  41.426  -56.415 1.00 8.41   ? 276 THR A1 O   1 
ATOM 1912 C CB  . THR A 1 276 ? 73.489  38.246  -56.074 1.00 6.32   ? 276 THR A1 CB  1 
ATOM 1913 O OG1 . THR A 1 276 ? 72.136  38.702  -56.125 1.00 8.13   ? 276 THR A1 OG1 1 
ATOM 1914 C CG2 . THR A 1 276 ? 73.570  37.048  -55.146 1.00 7.14   ? 276 THR A1 CG2 1 
ATOM 1915 N N   . HIS A 1 277 ? 75.188  40.595  -57.574 1.00 6.95   ? 277 HIS A1 N   1 
ATOM 1916 C CA  . HIS A 1 277 ? 75.210  41.727  -58.485 1.00 6.80   ? 277 HIS A1 CA  1 
ATOM 1917 C C   . HIS A 1 277 ? 74.657  41.341  -59.854 1.00 8.21   ? 277 HIS A1 C   1 
ATOM 1918 O O   . HIS A 1 277 ? 74.376  40.177  -60.135 1.00 10.04  ? 277 HIS A1 O   1 
ATOM 1919 C CB  . HIS A 1 277 ? 76.626  42.281  -58.620 1.00 4.21   ? 277 HIS A1 CB  1 
ATOM 1920 C CG  . HIS A 1 277 ? 77.558  41.395  -59.380 1.00 2.32   ? 277 HIS A1 CG  1 
ATOM 1921 N ND1 . HIS A 1 277 ? 78.151  40.288  -58.823 1.00 2.13   ? 277 HIS A1 ND1 1 
ATOM 1922 C CD2 . HIS A 1 277 ? 78.015  41.467  -60.650 1.00 2.26   ? 277 HIS A1 CD2 1 
ATOM 1923 C CE1 . HIS A 1 277 ? 78.924  39.707  -59.720 1.00 2.00   ? 277 HIS A1 CE1 1 
ATOM 1924 N NE2 . HIS A 1 277 ? 78.862  40.405  -60.836 1.00 2.01   ? 277 HIS A1 NE2 1 
ATOM 1925 N N   . THR A 1 278 ? 74.480  42.343  -60.708 1.00 8.67   ? 278 THR A1 N   1 
ATOM 1926 C CA  . THR A 1 278 ? 74.019  42.140  -62.075 1.00 10.30  ? 278 THR A1 CA  1 
ATOM 1927 C C   . THR A 1 278 ? 75.134  42.469  -63.054 1.00 10.89  ? 278 THR A1 C   1 
ATOM 1928 O O   . THR A 1 278 ? 75.783  43.511  -62.939 1.00 9.41   ? 278 THR A1 O   1 
ATOM 1929 C CB  . THR A 1 278 ? 72.808  43.011  -62.391 1.00 10.71  ? 278 THR A1 CB  1 
ATOM 1930 O OG1 . THR A 1 278 ? 73.159  44.387  -62.221 1.00 11.06  ? 278 THR A1 OG1 1 
ATOM 1931 C CG2 . THR A 1 278 ? 71.665  42.675  -61.481 1.00 7.52   ? 278 THR A1 CG2 1 
ATOM 1932 N N   . TRP A 1 279 ? 75.346  41.586  -64.025 1.00 11.08  ? 279 TRP A1 N   1 
ATOM 1933 C CA  . TRP A 1 279 ? 76.340  41.821  -65.059 1.00 10.09  ? 279 TRP A1 CA  1 
ATOM 1934 C C   . TRP A 1 279 ? 75.743  42.307  -66.367 1.00 10.95  ? 279 TRP A1 C   1 
ATOM 1935 O O   . TRP A 1 279 ? 76.497  42.640  -67.284 1.00 12.81  ? 279 TRP A1 O   1 
ATOM 1936 C CB  . TRP A 1 279 ? 77.147  40.546  -65.328 1.00 8.61   ? 279 TRP A1 CB  1 
ATOM 1937 C CG  . TRP A 1 279 ? 76.328  39.396  -65.804 1.00 7.90   ? 279 TRP A1 CG  1 
ATOM 1938 C CD1 . TRP A 1 279 ? 75.732  38.447  -65.034 1.00 8.21   ? 279 TRP A1 CD1 1 
ATOM 1939 C CD2 . TRP A 1 279 ? 76.022  39.061  -67.159 1.00 8.60   ? 279 TRP A1 CD2 1 
ATOM 1940 N NE1 . TRP A 1 279 ? 75.067  37.550  -65.822 1.00 7.48   ? 279 TRP A1 NE1 1 
ATOM 1941 C CE2 . TRP A 1 279 ? 75.230  37.907  -67.133 1.00 8.88   ? 279 TRP A1 CE2 1 
ATOM 1942 C CE3 . TRP A 1 279 ? 76.337  39.632  -68.394 1.00 9.55   ? 279 TRP A1 CE3 1 
ATOM 1943 C CZ2 . TRP A 1 279 ? 74.753  37.313  -68.288 1.00 9.60   ? 279 TRP A1 CZ2 1 
ATOM 1944 C CZ3 . TRP A 1 279 ? 75.854  39.051  -69.532 1.00 9.48   ? 279 TRP A1 CZ3 1 
ATOM 1945 C CH2 . TRP A 1 279 ? 75.075  37.900  -69.475 1.00 9.47   ? 279 TRP A1 CH2 1 
ATOM 1946 N N   . GLN A 1 280 ? 74.422  42.352  -66.477 1.00 10.23  ? 280 GLN A1 N   1 
ATOM 1947 C CA  . GLN A 1 280 ? 73.791  42.643  -67.752 1.00 9.71   ? 280 GLN A1 CA  1 
ATOM 1948 C C   . GLN A 1 280 ? 73.557  44.131  -67.917 1.00 11.07  ? 280 GLN A1 C   1 
ATOM 1949 O O   . GLN A 1 280 ? 72.961  44.782  -67.058 1.00 13.55  ? 280 GLN A1 O   1 
ATOM 1950 C CB  . GLN A 1 280 ? 72.468  41.900  -67.864 1.00 6.51   ? 280 GLN A1 CB  1 
ATOM 1951 C CG  . GLN A 1 280 ? 72.593  40.508  -68.409 1.00 5.14   ? 280 GLN A1 CG  1 
ATOM 1952 C CD  . GLN A 1 280 ? 71.413  39.657  -68.075 1.00 7.54   ? 280 GLN A1 CD  1 
ATOM 1953 O OE1 . GLN A 1 280 ? 71.266  39.212  -66.947 1.00 9.24   ? 280 GLN A1 OE1 1 
ATOM 1954 N NE2 . GLN A 1 280 ? 70.555  39.427  -69.050 1.00 7.93   ? 280 GLN A1 NE2 1 
ATOM 1955 N N   . THR A 1 281 ? 74.025  44.666  -69.032 1.00 10.62  ? 281 THR A1 N   1 
ATOM 1956 C CA  . THR A 1 281 ? 73.724  46.024  -69.448 1.00 9.09   ? 281 THR A1 CA  1 
ATOM 1957 C C   . THR A 1 281 ? 72.505  45.953  -70.346 1.00 8.21   ? 281 THR A1 C   1 
ATOM 1958 O O   . THR A 1 281 ? 71.833  44.927  -70.421 1.00 8.61   ? 281 THR A1 O   1 
ATOM 1959 C CB  . THR A 1 281 ? 74.916  46.666  -70.156 1.00 11.36  ? 281 THR A1 CB  1 
ATOM 1960 O OG1 . THR A 1 281 ? 75.014  46.143  -71.481 1.00 15.19  ? 281 THR A1 OG1 1 
ATOM 1961 C CG2 . THR A 1 281 ? 76.192  46.373  -69.409 1.00 13.89  ? 281 THR A1 CG2 1 
ATOM 1962 N N   . ASN A 1 282 ? 72.217  47.042  -71.039 1.00 6.34   ? 282 ASN A1 N   1 
ATOM 1963 C CA  . ASN A 1 282 ? 71.137  47.021  -72.019 1.00 3.36   ? 282 ASN A1 CA  1 
ATOM 1964 C C   . ASN A 1 282 ? 71.602  46.516  -73.376 1.00 4.11   ? 282 ASN A1 C   1 
ATOM 1965 O O   . ASN A 1 282 ? 71.239  47.072  -74.409 1.00 5.96   ? 282 ASN A1 O   1 
ATOM 1966 C CB  . ASN A 1 282 ? 70.573  48.435  -72.131 1.00 2.48   ? 282 ASN A1 CB  1 
ATOM 1967 C CG  . ASN A 1 282 ? 69.147  48.462  -72.589 1.00 3.78   ? 282 ASN A1 CG  1 
ATOM 1968 O OD1 . ASN A 1 282 ? 68.345  47.634  -72.184 1.00 5.69   ? 282 ASN A1 OD1 1 
ATOM 1969 N ND2 . ASN A 1 282 ? 68.818  49.416  -73.447 1.00 4.25   ? 282 ASN A1 ND2 1 
ATOM 1970 N N   . ARG A 1 283 ? 72.393  45.451  -73.394 1.00 3.05   ? 283 ARG A1 N   1 
ATOM 1971 C CA  . ARG A 1 283 ? 72.862  44.847  -74.630 1.00 2.94   ? 283 ARG A1 CA  1 
ATOM 1972 C C   . ARG A 1 283 ? 72.955  43.336  -74.498 1.00 3.16   ? 283 ARG A1 C   1 
ATOM 1973 O O   . ARG A 1 283 ? 73.416  42.676  -75.432 1.00 5.65   ? 283 ARG A1 O   1 
ATOM 1974 C CB  . ARG A 1 283 ? 74.220  45.409  -75.031 1.00 2.46   ? 283 ARG A1 CB  1 
ATOM 1975 C CG  . ARG A 1 283 ? 74.295  45.825  -76.468 1.00 2.74   ? 283 ARG A1 CG  1 
ATOM 1976 C CD  . ARG A 1 283 ? 75.676  45.616  -76.966 1.00 4.90   ? 283 ARG A1 CD  1 
ATOM 1977 N NE  . ARG A 1 283 ? 75.899  46.133  -78.303 1.00 6.87   ? 283 ARG A1 NE  1 
ATOM 1978 C CZ  . ARG A 1 283 ? 76.884  45.720  -79.081 1.00 7.54   ? 283 ARG A1 CZ  1 
ATOM 1979 N NH1 . ARG A 1 283 ? 77.700  44.775  -78.651 1.00 9.75   ? 283 ARG A1 NH1 1 
ATOM 1980 N NH2 . ARG A 1 283 ? 77.053  46.241  -80.281 1.00 6.98   ? 283 ARG A1 NH2 1 
ATOM 1981 N N   . ALA A 1 284 ? 72.560  42.782  -73.361 1.00 2.15   ? 284 ALA A1 N   1 
ATOM 1982 C CA  . ALA A 1 284 ? 72.560  41.360  -73.090 1.00 3.64   ? 284 ALA A1 CA  1 
ATOM 1983 C C   . ALA A 1 284 ? 71.209  40.950  -72.545 1.00 4.44   ? 284 ALA A1 C   1 
ATOM 1984 O O   . ALA A 1 284 ? 71.094  40.049  -71.714 1.00 5.30   ? 284 ALA A1 O   1 
ATOM 1985 C CB  . ALA A 1 284 ? 73.678  40.984  -72.127 1.00 2.09   ? 284 ALA A1 CB  1 
ATOM 1986 N N   . LEU A 1 285 ? 70.161  41.626  -73.000 1.00 3.72   ? 285 LEU A1 N   1 
ATOM 1987 C CA  . LEU A 1 285 ? 68.794  41.345  -72.600 1.00 2.30   ? 285 LEU A1 CA  1 
ATOM 1988 C C   . LEU A 1 285 ? 68.056  40.729  -73.775 1.00 3.12   ? 285 LEU A1 C   1 
ATOM 1989 O O   . LEU A 1 285 ? 68.023  41.313  -74.861 1.00 3.84   ? 285 LEU A1 O   1 
ATOM 1990 C CB  . LEU A 1 285 ? 68.082  42.621  -72.157 1.00 2.00   ? 285 LEU A1 CB  1 
ATOM 1991 C CG  . LEU A 1 285 ? 68.703  43.439  -71.031 1.00 2.00   ? 285 LEU A1 CG  1 
ATOM 1992 C CD1 . LEU A 1 285 ? 67.887  44.679  -70.820 1.00 2.08   ? 285 LEU A1 CD1 1 
ATOM 1993 C CD2 . LEU A 1 285 ? 68.748  42.635  -69.767 1.00 2.00   ? 285 LEU A1 CD2 1 
ATOM 1994 N N   . GLY A 1 286 ? 67.474  39.559  -73.565 1.00 3.78   ? 286 GLY A1 N   1 
ATOM 1995 C CA  . GLY A 1 286 ? 66.626  38.958  -74.569 1.00 2.83   ? 286 GLY A1 CA  1 
ATOM 1996 C C   . GLY A 1 286 ? 67.292  37.837  -75.337 1.00 4.12   ? 286 GLY A1 C   1 
ATOM 1997 O O   . GLY A 1 286 ? 68.229  37.183  -74.882 1.00 5.54   ? 286 GLY A1 O   1 
ATOM 1998 N N   . LEU A 1 287 ? 66.784  37.628  -76.531 1.00 4.86   ? 287 LEU A1 N   1 
ATOM 1999 C CA  . LEU A 1 287 ? 67.171  36.551  -77.431 1.00 5.57   ? 287 LEU A1 CA  1 
ATOM 2000 C C   . LEU A 1 287 ? 68.330  36.990  -78.315 1.00 5.74   ? 287 LEU A1 C   1 
ATOM 2001 O O   . LEU A 1 287 ? 68.191  37.967  -79.059 1.00 4.42   ? 287 LEU A1 O   1 
ATOM 2002 C CB  . LEU A 1 287 ? 65.993  36.144  -78.299 1.00 4.58   ? 287 LEU A1 CB  1 
ATOM 2003 C CG  . LEU A 1 287 ? 66.034  34.773  -78.959 1.00 3.13   ? 287 LEU A1 CG  1 
ATOM 2004 C CD1 . LEU A 1 287 ? 66.176  33.692  -77.925 1.00 2.00   ? 287 LEU A1 CD1 1 
ATOM 2005 C CD2 . LEU A 1 287 ? 64.780  34.567  -79.759 1.00 2.09   ? 287 LEU A1 CD2 1 
ATOM 2006 N N   . PRO A 1 288 ? 69.466  36.304  -78.262 1.00 5.80   ? 288 PRO A1 N   1 
ATOM 2007 C CA  . PRO A 1 288 ? 70.588  36.629  -79.135 1.00 6.05   ? 288 PRO A1 CA  1 
ATOM 2008 C C   . PRO A 1 288 ? 70.264  36.301  -80.581 1.00 6.70   ? 288 PRO A1 C   1 
ATOM 2009 O O   . PRO A 1 288 ? 69.354  35.503  -80.845 1.00 5.44   ? 288 PRO A1 O   1 
ATOM 2010 C CB  . PRO A 1 288 ? 71.713  35.735  -78.590 1.00 5.10   ? 288 PRO A1 CB  1 
ATOM 2011 C CG  . PRO A 1 288 ? 71.310  35.413  -77.229 1.00 4.64   ? 288 PRO A1 CG  1 
ATOM 2012 C CD  . PRO A 1 288 ? 69.839  35.284  -77.278 1.00 5.23   ? 288 PRO A1 CD  1 
ATOM 2013 N N   . PRO A 1 289 ? 70.952  36.911  -81.547 1.00 6.74   ? 289 PRO A1 N   1 
ATOM 2014 C CA  . PRO A 1 289 ? 70.648  36.614  -82.947 1.00 4.69   ? 289 PRO A1 CA  1 
ATOM 2015 C C   . PRO A 1 289 ? 71.111  35.221  -83.322 1.00 5.95   ? 289 PRO A1 C   1 
ATOM 2016 O O   . PRO A 1 289 ? 72.118  34.725  -82.821 1.00 6.96   ? 289 PRO A1 O   1 
ATOM 2017 C CB  . PRO A 1 289 ? 71.428  37.680  -83.719 1.00 4.08   ? 289 PRO A1 CB  1 
ATOM 2018 C CG  . PRO A 1 289 ? 71.903  38.635  -82.719 1.00 4.75   ? 289 PRO A1 CG  1 
ATOM 2019 C CD  . PRO A 1 289 ? 72.020  37.912  -81.445 1.00 6.60   ? 289 PRO A1 CD  1 
ATOM 2020 N N   . PHE A 1 290 ? 70.349  34.586  -84.206 1.00 6.95   ? 290 PHE A1 N   1 
ATOM 2021 C CA  . PHE A 1 290 ? 70.604  33.201  -84.577 1.00 7.43   ? 290 PHE A1 CA  1 
ATOM 2022 C C   . PHE A 1 290 ? 71.845  33.129  -85.446 1.00 8.52   ? 290 PHE A1 C   1 
ATOM 2023 O O   . PHE A 1 290 ? 71.807  33.483  -86.626 1.00 11.53  ? 290 PHE A1 O   1 
ATOM 2024 C CB  . PHE A 1 290 ? 69.408  32.604  -85.305 1.00 7.91   ? 290 PHE A1 CB  1 
ATOM 2025 C CG  . PHE A 1 290 ? 69.593  31.170  -85.659 1.00 9.53   ? 290 PHE A1 CG  1 
ATOM 2026 C CD1 . PHE A 1 290 ? 69.931  30.254  -84.687 1.00 11.23  ? 290 PHE A1 CD1 1 
ATOM 2027 C CD2 . PHE A 1 290 ? 69.447  30.735  -86.958 1.00 9.92   ? 290 PHE A1 CD2 1 
ATOM 2028 C CE1 . PHE A 1 290 ? 70.114  28.935  -85.004 1.00 12.02  ? 290 PHE A1 CE1 1 
ATOM 2029 C CE2 . PHE A 1 290 ? 69.632  29.416  -87.279 1.00 9.38   ? 290 PHE A1 CE2 1 
ATOM 2030 C CZ  . PHE A 1 290 ? 69.963  28.516  -86.302 1.00 10.74  ? 290 PHE A1 CZ  1 
ATOM 2031 N N   . LEU A 1 291 ? 72.948  32.675  -84.863 1.00 9.81   ? 291 LEU A1 N   1 
ATOM 2032 C CA  . LEU A 1 291 ? 74.183  32.479  -85.605 1.00 9.71   ? 291 LEU A1 CA  1 
ATOM 2033 C C   . LEU A 1 291 ? 74.025  31.245  -86.473 1.00 12.29  ? 291 LEU A1 C   1 
ATOM 2034 O O   . LEU A 1 291 ? 74.173  30.123  -85.986 1.00 14.31  ? 291 LEU A1 O   1 
ATOM 2035 C CB  . LEU A 1 291 ? 75.363  32.290  -84.661 1.00 5.59   ? 291 LEU A1 CB  1 
ATOM 2036 C CG  . LEU A 1 291 ? 75.673  33.265  -83.538 1.00 2.94   ? 291 LEU A1 CG  1 
ATOM 2037 C CD1 . LEU A 1 291 ? 76.763  32.664  -82.692 1.00 2.18   ? 291 LEU A1 CD1 1 
ATOM 2038 C CD2 . LEU A 1 291 ? 76.103  34.595  -84.070 1.00 2.00   ? 291 LEU A1 CD2 1 
ATOM 2039 N N   . ASN A 1 292 ? 73.716  31.431  -87.747 1.00 15.19  ? 292 ASN A1 N   1 
ATOM 2040 C CA  . ASN A 1 292 ? 73.778  30.336  -88.706 1.00 15.12  ? 292 ASN A1 CA  1 
ATOM 2041 C C   . ASN A 1 292 ? 75.095  30.436  -89.468 1.00 16.15  ? 292 ASN A1 C   1 
ATOM 2042 O O   . ASN A 1 292 ? 75.120  30.408  -90.701 1.00 18.64  ? 292 ASN A1 O   1 
ATOM 2043 C CB  . ASN A 1 292 ? 72.570  30.361  -89.635 1.00 16.42  ? 292 ASN A1 CB  1 
ATOM 2044 C CG  . ASN A 1 292 ? 72.189  31.755  -90.045 1.00 19.02  ? 292 ASN A1 CG  1 
ATOM 2045 O OD1 . ASN A 1 292 ? 72.873  32.717  -89.714 1.00 20.36  ? 292 ASN A1 OD1 1 
ATOM 2046 N ND2 . ASN A 1 292 ? 71.082  31.878  -90.758 1.00 20.78  ? 292 ASN A1 ND2 1 
ATOM 2047 N N   . SER A 1 293 ? 76.188  30.553  -88.708 1.00 16.47  ? 293 SER A1 N   1 
ATOM 2048 C CA  . SER A 1 293 ? 77.538  30.249  -89.175 1.00 17.39  ? 293 SER A1 CA  1 
ATOM 2049 C C   . SER A 1 293 ? 78.360  30.023  -87.908 1.00 16.96  ? 293 SER A1 C   1 
ATOM 2050 O O   . SER A 1 293 ? 78.748  30.988  -87.248 1.00 16.39  ? 293 SER A1 O   1 
ATOM 2051 C CB  . SER A 1 293 ? 78.120  31.365  -90.027 1.00 19.37  ? 293 SER A1 CB  1 
ATOM 2052 O OG  . SER A 1 293 ? 77.667  31.267  -91.363 1.00 24.90  ? 293 SER A1 OG  1 
ATOM 2053 N N   . LEU A 1 294 ? 78.600  28.817  -87.591 1.00 16.47  ? 294 LEU A1 N   1 
ATOM 2054 C CA  . LEU A 1 294 ? 79.275  28.554  -86.331 1.00 17.68  ? 294 LEU A1 CA  1 
ATOM 2055 C C   . LEU A 1 294 ? 80.740  28.198  -86.576 1.00 19.83  ? 294 LEU A1 C   1 
ATOM 2056 O O   . LEU A 1 294 ? 81.075  27.641  -87.624 1.00 21.75  ? 294 LEU A1 O   1 
ATOM 2057 C CB  . LEU A 1 294 ? 78.572  27.419  -85.592 1.00 16.07  ? 294 LEU A1 CB  1 
ATOM 2058 C CG  . LEU A 1 294 ? 77.177  27.795  -85.103 1.00 15.20  ? 294 LEU A1 CG  1 
ATOM 2059 C CD1 . LEU A 1 294 ? 76.499  26.630  -84.430 1.00 13.58  ? 294 LEU A1 CD1 1 
ATOM 2060 C CD2 . LEU A 1 294 ? 77.260  28.961  -84.159 1.00 15.57  ? 294 LEU A1 CD2 1 
ATOM 2061 N N   . PRO A 1 295 ? 81.645  28.521  -85.647 1.00 20.69  ? 295 PRO A1 N   1 
ATOM 2062 C CA  . PRO A 1 295 ? 83.064  28.230  -85.879 1.00 20.48  ? 295 PRO A1 CA  1 
ATOM 2063 C C   . PRO A 1 295 ? 83.357  26.741  -85.811 1.00 20.70  ? 295 PRO A1 C   1 
ATOM 2064 O O   . PRO A 1 295 ? 82.897  26.028  -84.916 1.00 18.19  ? 295 PRO A1 O   1 
ATOM 2065 C CB  . PRO A 1 295 ? 83.771  28.988  -84.754 1.00 20.70  ? 295 PRO A1 CB  1 
ATOM 2066 C CG  . PRO A 1 295 ? 82.763  29.114  -83.700 1.00 20.53  ? 295 PRO A1 CG  1 
ATOM 2067 C CD  . PRO A 1 295 ? 81.449  29.260  -84.390 1.00 20.88  ? 295 PRO A1 CD  1 
ATOM 2068 N N   . GLN A 1 296 ? 84.125  26.272  -86.792 1.00 24.54  ? 296 GLN A1 N   1 
ATOM 2069 C CA  . GLN A 1 296 ? 84.366  24.852  -86.982 1.00 30.54  ? 296 GLN A1 CA  1 
ATOM 2070 C C   . GLN A 1 296 ? 85.612  24.353  -86.274 1.00 29.94  ? 296 GLN A1 C   1 
ATOM 2071 O O   . GLN A 1 296 ? 85.694  23.160  -85.964 1.00 30.85  ? 296 GLN A1 O   1 
ATOM 2072 C CB  . GLN A 1 296 ? 84.468  24.536  -88.479 1.00 35.94  ? 296 GLN A1 CB  1 
ATOM 2073 C CG  . GLN A 1 296 ? 83.263  24.972  -89.320 1.00 43.75  ? 296 GLN A1 CG  1 
ATOM 2074 C CD  . GLN A 1 296 ? 81.899  24.615  -88.725 1.00 48.40  ? 296 GLN A1 CD  1 
ATOM 2075 O OE1 . GLN A 1 296 ? 81.695  23.527  -88.178 1.00 51.64  ? 296 GLN A1 OE1 1 
ATOM 2076 N NE2 . GLN A 1 296 ? 80.959  25.547  -88.831 1.00 49.25  ? 296 GLN A1 NE2 1 
ATOM 2077 N N   . SER A 1 297 ? 86.579  25.225  -86.015 1.00 28.18  ? 297 SER A1 N   1 
ATOM 2078 C CA  . SER A 1 297 ? 87.723  24.875  -85.194 1.00 27.45  ? 297 SER A1 CA  1 
ATOM 2079 C C   . SER A 1 297 ? 87.754  25.818  -84.008 1.00 25.39  ? 297 SER A1 C   1 
ATOM 2080 O O   . SER A 1 297 ? 87.780  27.038  -84.182 1.00 22.54  ? 297 SER A1 O   1 
ATOM 2081 C CB  . SER A 1 297 ? 89.036  24.961  -85.976 1.00 30.11  ? 297 SER A1 CB  1 
ATOM 2082 O OG  . SER A 1 297 ? 90.149  24.827  -85.109 1.00 36.83  ? 297 SER A1 OG  1 
ATOM 2083 N N   . GLU A 1 298 ? 87.732  25.249  -82.810 1.00 25.28  ? 298 GLU A1 N   1 
ATOM 2084 C CA  . GLU A 1 298 ? 87.676  26.049  -81.598 1.00 27.79  ? 298 GLU A1 CA  1 
ATOM 2085 C C   . GLU A 1 298 ? 89.001  26.777  -81.378 1.00 29.91  ? 298 GLU A1 C   1 
ATOM 2086 O O   . GLU A 1 298 ? 90.085  26.200  -81.480 1.00 30.47  ? 298 GLU A1 O   1 
ATOM 2087 C CB  . GLU A 1 298 ? 87.336  25.164  -80.394 1.00 27.02  ? 298 GLU A1 CB  1 
ATOM 2088 C CG  . GLU A 1 298 ? 85.827  24.926  -80.153 1.00 27.83  ? 298 GLU A1 CG  1 
ATOM 2089 C CD  . GLU A 1 298 ? 85.206  23.862  -81.045 1.00 27.58  ? 298 GLU A1 CD  1 
ATOM 2090 O OE1 . GLU A 1 298 ? 85.932  22.950  -81.479 1.00 27.22  ? 298 GLU A1 OE1 1 
ATOM 2091 O OE2 . GLU A 1 298 ? 83.985  23.925  -81.291 1.00 26.02  ? 298 GLU A1 OE2 1 
ATOM 2092 N N   . GLY A 1 299 ? 88.899  28.064  -81.077 1.00 32.73  ? 299 GLY A1 N   1 
ATOM 2093 C CA  . GLY A 1 299 ? 90.076  28.902  -80.959 1.00 36.61  ? 299 GLY A1 CA  1 
ATOM 2094 C C   . GLY A 1 299 ? 89.690  30.305  -80.523 1.00 39.37  ? 299 GLY A1 C   1 
ATOM 2095 O O   . GLY A 1 299 ? 88.571  30.544  -80.074 1.00 41.66  ? 299 GLY A1 O   1 
ATOM 2096 N N   . ALA A 1 300 ? 90.644  31.224  -80.679 1.00 40.17  ? 300 ALA A1 N   1 
ATOM 2097 C CA  . ALA A 1 300 ? 90.516  32.570  -80.142 1.00 40.31  ? 300 ALA A1 CA  1 
ATOM 2098 C C   . ALA A 1 300 ? 90.089  33.617  -81.161 1.00 38.77  ? 300 ALA A1 C   1 
ATOM 2099 O O   . ALA A 1 300 ? 89.627  34.687  -80.755 1.00 40.33  ? 300 ALA A1 O   1 
ATOM 2100 C CB  . ALA A 1 300 ? 91.839  33.018  -79.502 1.00 42.33  ? 300 ALA A1 CB  1 
ATOM 2101 N N   . THR A 1 301 ? 90.233  33.355  -82.456 1.00 36.18  ? 301 THR A1 N   1 
ATOM 2102 C CA  . THR A 1 301 ? 89.783  34.281  -83.485 1.00 34.91  ? 301 THR A1 CA  1 
ATOM 2103 C C   . THR A 1 301 ? 88.764  33.633  -84.412 1.00 33.69  ? 301 THR A1 C   1 
ATOM 2104 O O   . THR A 1 301 ? 88.492  34.142  -85.500 1.00 35.92  ? 301 THR A1 O   1 
ATOM 2105 C CB  . THR A 1 301 ? 90.960  34.820  -84.291 1.00 36.25  ? 301 THR A1 CB  1 
ATOM 2106 O OG1 . THR A 1 301 ? 90.470  35.682  -85.325 1.00 37.06  ? 301 THR A1 OG1 1 
ATOM 2107 C CG2 . THR A 1 301 ? 91.747  33.679  -84.914 1.00 37.21  ? 301 THR A1 CG2 1 
ATOM 2108 N N   . ASN A 1 302 ? 88.194  32.508  -83.996 1.00 30.21  ? 302 ASN A1 N   1 
ATOM 2109 C CA  . ASN A 1 302 ? 87.177  31.804  -84.767 1.00 26.89  ? 302 ASN A1 CA  1 
ATOM 2110 C C   . ASN A 1 302 ? 85.816  32.268  -84.265 1.00 23.55  ? 302 ASN A1 C   1 
ATOM 2111 O O   . ASN A 1 302 ? 85.274  31.707  -83.310 1.00 23.01  ? 302 ASN A1 O   1 
ATOM 2112 C CB  . ASN A 1 302 ? 87.341  30.299  -84.640 1.00 28.71  ? 302 ASN A1 CB  1 
ATOM 2113 C CG  . ASN A 1 302 ? 88.364  29.752  -85.606 1.00 31.17  ? 302 ASN A1 CG  1 
ATOM 2114 O OD1 . ASN A 1 302 ? 88.022  29.074  -86.573 1.00 33.27  ? 302 ASN A1 OD1 1 
ATOM 2115 N ND2 . ASN A 1 302 ? 89.631  30.056  -85.357 1.00 32.23  ? 302 ASN A1 ND2 1 
ATOM 2116 N N   . PHE A 1 303 ? 85.272  33.294  -84.902 1.00 19.98  ? 303 PHE A1 N   1 
ATOM 2117 C CA  . PHE A 1 303 ? 84.017  33.889  -84.483 1.00 18.47  ? 303 PHE A1 CA  1 
ATOM 2118 C C   . PHE A 1 303 ? 82.849  33.283  -85.244 1.00 18.37  ? 303 PHE A1 C   1 
ATOM 2119 O O   . PHE A 1 303 ? 82.949  32.948  -86.425 1.00 20.36  ? 303 PHE A1 O   1 
ATOM 2120 C CB  . PHE A 1 303 ? 84.029  35.400  -84.700 1.00 18.18  ? 303 PHE A1 CB  1 
ATOM 2121 C CG  . PHE A 1 303 ? 85.219  36.084  -84.118 1.00 18.10  ? 303 PHE A1 CG  1 
ATOM 2122 C CD1 . PHE A 1 303 ? 85.251  36.417  -82.778 1.00 18.59  ? 303 PHE A1 CD1 1 
ATOM 2123 C CD2 . PHE A 1 303 ? 86.296  36.409  -84.912 1.00 18.67  ? 303 PHE A1 CD2 1 
ATOM 2124 C CE1 . PHE A 1 303 ? 86.340  37.050  -82.238 1.00 18.98  ? 303 PHE A1 CE1 1 
ATOM 2125 C CE2 . PHE A 1 303 ? 87.391  37.041  -84.380 1.00 19.15  ? 303 PHE A1 CE2 1 
ATOM 2126 C CZ  . PHE A 1 303 ? 87.412  37.365  -83.039 1.00 19.25  ? 303 PHE A1 CZ  1 
ATOM 2127 N N   . GLY A 1 304 ? 81.735  33.148  -84.545 1.00 17.32  ? 304 GLY A1 N   1 
ATOM 2128 C CA  . GLY A 1 304 ? 80.492  32.829  -85.198 1.00 15.11  ? 304 GLY A1 CA  1 
ATOM 2129 C C   . GLY A 1 304 ? 79.927  34.040  -85.898 1.00 14.34  ? 304 GLY A1 C   1 
ATOM 2130 O O   . GLY A 1 304 ? 80.226  35.183  -85.565 1.00 13.46  ? 304 GLY A1 O   1 
ATOM 2131 N N   . ASP A 1 305 ? 79.102  33.787  -86.906 1.00 14.37  ? 305 ASP A1 N   1 
ATOM 2132 C CA  . ASP A 1 305 ? 78.554  34.863  -87.710 1.00 15.38  ? 305 ASP A1 CA  1 
ATOM 2133 C C   . ASP A 1 305 ? 77.064  34.649  -87.902 1.00 13.22  ? 305 ASP A1 C   1 
ATOM 2134 O O   . ASP A 1 305 ? 76.592  33.524  -88.068 1.00 11.20  ? 305 ASP A1 O   1 
ATOM 2135 C CB  . ASP A 1 305 ? 79.251  34.955  -89.072 1.00 22.15  ? 305 ASP A1 CB  1 
ATOM 2136 C CG  . ASP A 1 305 ? 80.753  35.141  -88.951 1.00 28.07  ? 305 ASP A1 CG  1 
ATOM 2137 O OD1 . ASP A 1 305 ? 81.186  36.070  -88.233 1.00 31.35  ? 305 ASP A1 OD1 1 
ATOM 2138 O OD2 . ASP A 1 305 ? 81.501  34.358  -89.573 1.00 30.67  ? 305 ASP A1 OD2 1 
ATOM 2139 N N   . ILE A 1 306 ? 76.325  35.749  -87.899 1.00 11.55  ? 306 ILE A1 N   1 
ATOM 2140 C CA  . ILE A 1 306 ? 74.928  35.764  -88.303 1.00 11.88  ? 306 ILE A1 CA  1 
ATOM 2141 C C   . ILE A 1 306 ? 74.912  35.817  -89.821 1.00 13.10  ? 306 ILE A1 C   1 
ATOM 2142 O O   . ILE A 1 306 ? 75.454  36.755  -90.417 1.00 16.54  ? 306 ILE A1 O   1 
ATOM 2143 C CB  . ILE A 1 306 ? 74.178  36.964  -87.703 1.00 9.98   ? 306 ILE A1 CB  1 
ATOM 2144 C CG1 . ILE A 1 306 ? 74.609  37.189  -86.258 1.00 8.49   ? 306 ILE A1 CG1 1 
ATOM 2145 C CG2 . ILE A 1 306 ? 72.685  36.750  -87.783 1.00 10.06  ? 306 ILE A1 CG2 1 
ATOM 2146 C CD1 . ILE A 1 306 ? 74.394  38.589  -85.773 1.00 5.61   ? 306 ILE A1 CD1 1 
ATOM 2147 N N   . GLY A 1 307 ? 74.301  34.822  -90.447 1.00 13.18  ? 307 GLY A1 N   1 
ATOM 2148 C CA  . GLY A 1 307 ? 74.362  34.725  -91.891 1.00 15.95  ? 307 GLY A1 CA  1 
ATOM 2149 C C   . GLY A 1 307 ? 73.525  35.714  -92.665 1.00 16.50  ? 307 GLY A1 C   1 
ATOM 2150 O O   . GLY A 1 307 ? 73.584  35.726  -93.896 1.00 20.46  ? 307 GLY A1 O   1 
ATOM 2151 N N   . VAL A 1 308 ? 72.750  36.551  -91.986 1.00 14.21  ? 308 VAL A1 N   1 
ATOM 2152 C CA  . VAL A 1 308 ? 71.870  37.516  -92.628 1.00 11.71  ? 308 VAL A1 CA  1 
ATOM 2153 C C   . VAL A 1 308 ? 72.525  38.885  -92.555 1.00 15.46  ? 308 VAL A1 C   1 
ATOM 2154 O O   . VAL A 1 308 ? 73.044  39.274  -91.503 1.00 16.72  ? 308 VAL A1 O   1 
ATOM 2155 C CB  . VAL A 1 308 ? 70.487  37.536  -91.957 1.00 7.64   ? 308 VAL A1 CB  1 
ATOM 2156 C CG1 . VAL A 1 308 ? 69.470  38.179  -92.868 1.00 5.05   ? 308 VAL A1 CG1 1 
ATOM 2157 C CG2 . VAL A 1 308 ? 70.066  36.139  -91.576 1.00 4.74   ? 308 VAL A1 CG2 1 
ATOM 2158 N N   . GLN A 1 309 ? 72.513  39.609  -93.671 1.00 17.68  ? 309 GLN A1 N   1 
ATOM 2159 C CA  . GLN A 1 309 ? 73.022  40.968  -93.654 1.00 19.97  ? 309 GLN A1 CA  1 
ATOM 2160 C C   . GLN A 1 309 ? 72.050  41.866  -92.895 1.00 17.98  ? 309 GLN A1 C   1 
ATOM 2161 O O   . GLN A 1 309 ? 70.875  41.541  -92.726 1.00 17.63  ? 309 GLN A1 O   1 
ATOM 2162 C CB  . GLN A 1 309 ? 73.263  41.474  -95.073 1.00 27.74  ? 309 GLN A1 CB  1 
ATOM 2163 C CG  . GLN A 1 309 ? 72.019  41.837  -95.831 1.00 38.74  ? 309 GLN A1 CG  1 
ATOM 2164 C CD  . GLN A 1 309 ? 72.168  41.637  -97.320 1.00 45.37  ? 309 GLN A1 CD  1 
ATOM 2165 O OE1 . GLN A 1 309 ? 72.608  40.584  -97.774 1.00 51.02  ? 309 GLN A1 OE1 1 
ATOM 2166 N NE2 . GLN A 1 309 ? 71.796  42.649  -98.091 1.00 46.33  ? 309 GLN A1 NE2 1 
ATOM 2167 N N   . GLN A 1 310 ? 72.563  43.007  -92.426 1.00 15.72  ? 310 GLN A1 N   1 
ATOM 2168 C CA  . GLN A 1 310 ? 71.894  43.767  -91.374 1.00 14.14  ? 310 GLN A1 CA  1 
ATOM 2169 C C   . GLN A 1 310 ? 70.601  44.421  -91.830 1.00 14.44  ? 310 GLN A1 C   1 
ATOM 2170 O O   . GLN A 1 310 ? 69.704  44.616  -91.007 1.00 14.43  ? 310 GLN A1 O   1 
ATOM 2171 C CB  . GLN A 1 310 ? 72.831  44.835  -90.818 1.00 12.97  ? 310 GLN A1 CB  1 
ATOM 2172 C CG  . GLN A 1 310 ? 73.822  44.309  -89.811 1.00 12.38  ? 310 GLN A1 CG  1 
ATOM 2173 C CD  . GLN A 1 310 ? 75.010  45.219  -89.645 1.00 13.04  ? 310 GLN A1 CD  1 
ATOM 2174 O OE1 . GLN A 1 310 ? 75.375  45.946  -90.562 1.00 13.59  ? 310 GLN A1 OE1 1 
ATOM 2175 N NE2 . GLN A 1 310 ? 75.631  45.174  -88.479 1.00 13.16  ? 310 GLN A1 NE2 1 
ATOM 2176 N N   . ASP A 1 311 ? 70.470  44.743  -93.113 1.00 15.63  ? 311 ASP A1 N   1 
ATOM 2177 C CA  . ASP A 1 311 ? 69.260  45.368  -93.626 1.00 17.39  ? 311 ASP A1 CA  1 
ATOM 2178 C C   . ASP A 1 311 ? 68.234  44.341  -94.081 1.00 17.25  ? 311 ASP A1 C   1 
ATOM 2179 O O   . ASP A 1 311 ? 67.194  44.710  -94.631 1.00 16.87  ? 311 ASP A1 O   1 
ATOM 2180 C CB  . ASP A 1 311 ? 69.601  46.323  -94.767 1.00 21.06  ? 311 ASP A1 CB  1 
ATOM 2181 C CG  . ASP A 1 311 ? 70.528  45.702  -95.787 1.00 25.36  ? 311 ASP A1 CG  1 
ATOM 2182 O OD1 . ASP A 1 311 ? 71.722  45.510  -95.473 1.00 26.02  ? 311 ASP A1 OD1 1 
ATOM 2183 O OD2 . ASP A 1 311 ? 70.067  45.406  -96.909 1.00 29.67  ? 311 ASP A1 OD2 1 
ATOM 2184 N N   . LYS A 1 312 ? 68.497  43.055  -93.850 1.00 17.69  ? 312 LYS A1 N   1 
ATOM 2185 C CA  . LYS A 1 312 ? 67.561  41.995  -94.195 1.00 18.60  ? 312 LYS A1 CA  1 
ATOM 2186 C C   . LYS A 1 312 ? 67.193  41.128  -93.000 1.00 18.15  ? 312 LYS A1 C   1 
ATOM 2187 O O   . LYS A 1 312 ? 66.640  40.041  -93.190 1.00 19.58  ? 312 LYS A1 O   1 
ATOM 2188 C CB  . LYS A 1 312 ? 68.133  41.109  -95.305 1.00 21.49  ? 312 LYS A1 CB  1 
ATOM 2189 C CG  . LYS A 1 312 ? 68.379  41.814  -96.623 1.00 24.94  ? 312 LYS A1 CG  1 
ATOM 2190 C CD  . LYS A 1 312 ? 67.109  42.425  -97.162 1.00 28.96  ? 312 LYS A1 CD  1 
ATOM 2191 C CE  . LYS A 1 312 ? 67.320  43.004  -98.543 1.00 32.48  ? 312 LYS A1 CE  1 
ATOM 2192 N NZ  . LYS A 1 312 ? 67.719  41.948  -99.504 1.00 36.45  ? 312 LYS A1 NZ  1 
ATOM 2193 N N   . ARG A 1 313 ? 67.495  41.564  -91.781 1.00 16.13  ? 313 ARG A1 N   1 
ATOM 2194 C CA  . ARG A 1 313 ? 67.195  40.782  -90.594 1.00 12.10  ? 313 ARG A1 CA  1 
ATOM 2195 C C   . ARG A 1 313 ? 65.771  41.046  -90.123 1.00 12.06  ? 313 ARG A1 C   1 
ATOM 2196 O O   . ARG A 1 313 ? 65.120  42.010  -90.523 1.00 14.11  ? 313 ARG A1 O   1 
ATOM 2197 C CB  . ARG A 1 313 ? 68.195  41.095  -89.488 1.00 9.58   ? 313 ARG A1 CB  1 
ATOM 2198 C CG  . ARG A 1 313 ? 69.476  40.322  -89.598 1.00 7.54   ? 313 ARG A1 CG  1 
ATOM 2199 C CD  . ARG A 1 313 ? 70.509  40.826  -88.629 1.00 6.93   ? 313 ARG A1 CD  1 
ATOM 2200 N NE  . ARG A 1 313 ? 71.844  40.441  -89.058 1.00 6.84   ? 313 ARG A1 NE  1 
ATOM 2201 C CZ  . ARG A 1 313 ? 72.960  40.916  -88.529 1.00 6.62   ? 313 ARG A1 CZ  1 
ATOM 2202 N NH1 . ARG A 1 313 ? 72.900  41.793  -87.542 1.00 5.08   ? 313 ARG A1 NH1 1 
ATOM 2203 N NH2 . ARG A 1 313 ? 74.131  40.507  -88.984 1.00 6.33   ? 313 ARG A1 NH2 1 
ATOM 2204 N N   . ARG A 1 314 ? 65.288  40.175  -89.243 1.00 12.07  ? 314 ARG A1 N   1 
ATOM 2205 C CA  . ARG A 1 314 ? 63.968  40.303  -88.655 1.00 11.15  ? 314 ARG A1 CA  1 
ATOM 2206 C C   . ARG A 1 314 ? 64.100  40.576  -87.166 1.00 10.14  ? 314 ARG A1 C   1 
ATOM 2207 O O   . ARG A 1 314 ? 65.027  40.099  -86.509 1.00 10.91  ? 314 ARG A1 O   1 
ATOM 2208 C CB  . ARG A 1 314 ? 63.138  39.053  -88.895 1.00 12.58  ? 314 ARG A1 CB  1 
ATOM 2209 C CG  . ARG A 1 314 ? 63.230  38.538  -90.308 1.00 16.68  ? 314 ARG A1 CG  1 
ATOM 2210 C CD  . ARG A 1 314 ? 62.106  37.589  -90.604 1.00 20.20  ? 314 ARG A1 CD  1 
ATOM 2211 N NE  . ARG A 1 314 ? 62.174  36.430  -89.730 1.00 25.11  ? 314 ARG A1 NE  1 
ATOM 2212 C CZ  . ARG A 1 314 ? 62.602  35.236  -90.114 1.00 26.93  ? 314 ARG A1 CZ  1 
ATOM 2213 N NH1 . ARG A 1 314 ? 62.988  35.043  -91.366 1.00 29.21  ? 314 ARG A1 NH1 1 
ATOM 2214 N NH2 . ARG A 1 314 ? 62.637  34.235  -89.247 1.00 26.48  ? 314 ARG A1 NH2 1 
ATOM 2215 N N   . GLY A 1 315 ? 63.159  41.349  -86.643 1.00 8.49   ? 315 GLY A1 N   1 
ATOM 2216 C CA  . GLY A 1 315 ? 63.209  41.833  -85.280 1.00 7.37   ? 315 GLY A1 CA  1 
ATOM 2217 C C   . GLY A 1 315 ? 62.539  43.183  -85.154 1.00 6.88   ? 315 GLY A1 C   1 
ATOM 2218 O O   . GLY A 1 315 ? 62.204  43.841  -86.135 1.00 9.05   ? 315 GLY A1 O   1 
ATOM 2219 N N   . VAL A 1 316 ? 62.336  43.581  -83.909 1.00 6.99   ? 316 VAL A1 N   1 
ATOM 2220 C CA  . VAL A 1 316 ? 61.674  44.842  -83.610 1.00 8.12   ? 316 VAL A1 CA  1 
ATOM 2221 C C   . VAL A 1 316 ? 62.731  45.904  -83.345 1.00 9.08   ? 316 VAL A1 C   1 
ATOM 2222 O O   . VAL A 1 316 ? 63.551  45.766  -82.434 1.00 9.82   ? 316 VAL A1 O   1 
ATOM 2223 C CB  . VAL A 1 316 ? 60.725  44.701  -82.416 1.00 8.09   ? 316 VAL A1 CB  1 
ATOM 2224 C CG1 . VAL A 1 316 ? 59.936  45.967  -82.250 1.00 7.48   ? 316 VAL A1 CG1 1 
ATOM 2225 C CG2 . VAL A 1 316 ? 59.804  43.530  -82.620 1.00 8.38   ? 316 VAL A1 CG2 1 
ATOM 2226 N N   . THR A 1 317 ? 62.716  46.957  -84.150 1.00 9.52   ? 317 THR A1 N   1 
ATOM 2227 C CA  . THR A 1 317 ? 63.571  48.115  -83.974 1.00 10.94  ? 317 THR A1 CA  1 
ATOM 2228 C C   . THR A 1 317 ? 62.700  49.274  -83.499 1.00 11.04  ? 317 THR A1 C   1 
ATOM 2229 O O   . THR A 1 317 ? 61.502  49.323  -83.777 1.00 9.80   ? 317 THR A1 O   1 
ATOM 2230 C CB  . THR A 1 317 ? 64.281  48.431  -85.289 1.00 11.08  ? 317 THR A1 CB  1 
ATOM 2231 O OG1 . THR A 1 317 ? 64.823  47.220  -85.817 1.00 12.07  ? 317 THR A1 OG1 1 
ATOM 2232 C CG2 . THR A 1 317 ? 65.434  49.389  -85.094 1.00 12.28  ? 317 THR A1 CG2 1 
ATOM 2233 N N   . GLN A 1 318 ? 63.278  50.217  -82.763 1.00 12.00  ? 318 GLN A1 N   1 
ATOM 2234 C CA  . GLN A 1 318 ? 62.496  51.370  -82.345 1.00 12.42  ? 318 GLN A1 CA  1 
ATOM 2235 C C   . GLN A 1 318 ? 62.930  52.597  -83.140 1.00 12.86  ? 318 GLN A1 C   1 
ATOM 2236 O O   . GLN A 1 318 ? 62.600  53.733  -82.790 1.00 14.38  ? 318 GLN A1 O   1 
ATOM 2237 C CB  . GLN A 1 318 ? 62.626  51.579  -80.833 1.00 13.09  ? 318 GLN A1 CB  1 
ATOM 2238 C CG  . GLN A 1 318 ? 61.513  52.385  -80.173 1.00 14.98  ? 318 GLN A1 CG  1 
ATOM 2239 C CD  . GLN A 1 318 ? 61.696  52.518  -78.693 1.00 15.77  ? 318 GLN A1 CD  1 
ATOM 2240 O OE1 . GLN A 1 318 ? 62.654  51.998  -78.132 1.00 16.02  ? 318 GLN A1 OE1 1 
ATOM 2241 N NE2 . GLN A 1 318 ? 60.790  53.233  -78.048 1.00 16.73  ? 318 GLN A1 NE2 1 
ATOM 2242 N N   . MET A 1 319 ? 63.640  52.387  -84.242 1.00 11.91  ? 319 MET A1 N   1 
ATOM 2243 C CA  . MET A 1 319 ? 64.230  53.488  -84.985 1.00 12.11  ? 319 MET A1 CA  1 
ATOM 2244 C C   . MET A 1 319 ? 63.378  53.946  -86.156 1.00 13.42  ? 319 MET A1 C   1 
ATOM 2245 O O   . MET A 1 319 ? 63.811  54.816  -86.911 1.00 16.77  ? 319 MET A1 O   1 
ATOM 2246 C CB  . MET A 1 319 ? 65.629  53.120  -85.462 1.00 10.53  ? 319 MET A1 CB  1 
ATOM 2247 C CG  . MET A 1 319 ? 66.586  52.898  -84.325 1.00 9.55   ? 319 MET A1 CG  1 
ATOM 2248 S SD  . MET A 1 319 ? 68.270  53.216  -84.826 1.00 10.73  ? 319 MET A1 SD  1 
ATOM 2249 C CE  . MET A 1 319 ? 68.241  54.999  -84.861 1.00 12.18  ? 319 MET A1 CE  1 
ATOM 2250 N N   . GLY A 1 320 ? 62.194  53.379  -86.336 1.00 14.68  ? 320 GLY A1 N   1 
ATOM 2251 C CA  . GLY A 1 320 ? 61.177  54.020  -87.146 1.00 16.15  ? 320 GLY A1 CA  1 
ATOM 2252 C C   . GLY A 1 320 ? 61.366  54.018  -88.648 1.00 17.72  ? 320 GLY A1 C   1 
ATOM 2253 O O   . GLY A 1 320 ? 60.484  53.559  -89.376 1.00 19.59  ? 320 GLY A1 O   1 
ATOM 2254 N N   . ASN A 1 321 ? 62.490  54.541  -89.133 1.00 17.45  ? 321 ASN A1 N   1 
ATOM 2255 C CA  . ASN A 1 321 ? 62.689  54.745  -90.561 1.00 15.60  ? 321 ASN A1 CA  1 
ATOM 2256 C C   . ASN A 1 321 ? 63.973  54.104  -91.071 1.00 14.80  ? 321 ASN A1 C   1 
ATOM 2257 O O   . ASN A 1 321 ? 64.462  54.462  -92.142 1.00 16.25  ? 321 ASN A1 O   1 
ATOM 2258 C CB  . ASN A 1 321 ? 62.675  56.237  -90.893 1.00 16.07  ? 321 ASN A1 CB  1 
ATOM 2259 C CG  . ASN A 1 321 ? 63.767  57.010  -90.177 1.00 16.72  ? 321 ASN A1 CG  1 
ATOM 2260 O OD1 . ASN A 1 321 ? 64.310  56.561  -89.172 1.00 18.37  ? 321 ASN A1 OD1 1 
ATOM 2261 N ND2 . ASN A 1 321 ? 64.082  58.189  -90.690 1.00 17.91  ? 321 ASN A1 ND2 1 
ATOM 2262 N N   . THR A 1 322 ? 64.544  53.166  -90.321 1.00 14.31  ? 322 THR A1 N   1 
ATOM 2263 C CA  . THR A 1 322 ? 65.721  52.445  -90.780 1.00 16.33  ? 322 THR A1 CA  1 
ATOM 2264 C C   . THR A 1 322 ? 65.410  50.960  -90.822 1.00 17.09  ? 322 THR A1 C   1 
ATOM 2265 O O   . THR A 1 322 ? 64.669  50.442  -89.985 1.00 19.43  ? 322 THR A1 O   1 
ATOM 2266 C CB  . THR A 1 322 ? 66.954  52.667  -89.887 1.00 17.74  ? 322 THR A1 CB  1 
ATOM 2267 O OG1 . THR A 1 322 ? 66.913  51.766  -88.776 1.00 20.01  ? 322 THR A1 OG1 1 
ATOM 2268 C CG2 . THR A 1 322 ? 67.011  54.088  -89.368 1.00 17.81  ? 322 THR A1 CG2 1 
ATOM 2269 N N   . ASN A 1 323 ? 65.996  50.277  -91.800 1.00 16.42  ? 323 ASN A1 N   1 
ATOM 2270 C CA  . ASN A 1 323 ? 65.849  48.839  -91.943 1.00 14.87  ? 323 ASN A1 CA  1 
ATOM 2271 C C   . ASN A 1 323 ? 66.992  48.065  -91.309 1.00 14.52  ? 323 ASN A1 C   1 
ATOM 2272 O O   . ASN A 1 323 ? 67.019  46.838  -91.408 1.00 16.82  ? 323 ASN A1 O   1 
ATOM 2273 C CB  . ASN A 1 323 ? 65.736  48.464  -93.419 1.00 15.01  ? 323 ASN A1 CB  1 
ATOM 2274 C CG  . ASN A 1 323 ? 64.572  49.135  -94.099 1.00 14.53  ? 323 ASN A1 CG  1 
ATOM 2275 O OD1 . ASN A 1 323 ? 63.742  49.767  -93.453 1.00 14.82  ? 323 ASN A1 OD1 1 
ATOM 2276 N ND2 . ASN A 1 323 ? 64.494  48.989  -95.410 1.00 14.80  ? 323 ASN A1 ND2 1 
ATOM 2277 N N   . TYR A 1 324 ? 67.934  48.748  -90.669 1.00 13.66  ? 324 TYR A1 N   1 
ATOM 2278 C CA  . TYR A 1 324 ? 69.046  48.076  -90.010 1.00 13.88  ? 324 TYR A1 CA  1 
ATOM 2279 C C   . TYR A 1 324 ? 68.579  47.519  -88.678 1.00 13.51  ? 324 TYR A1 C   1 
ATOM 2280 O O   . TYR A 1 324 ? 68.068  48.257  -87.832 1.00 15.56  ? 324 TYR A1 O   1 
ATOM 2281 C CB  . TYR A 1 324 ? 70.206  49.039  -89.803 1.00 16.42  ? 324 TYR A1 CB  1 
ATOM 2282 C CG  . TYR A 1 324 ? 70.931  49.398  -91.064 1.00 19.84  ? 324 TYR A1 CG  1 
ATOM 2283 C CD1 . TYR A 1 324 ? 71.725  48.469  -91.712 1.00 20.91  ? 324 TYR A1 CD1 1 
ATOM 2284 C CD2 . TYR A 1 324 ? 70.822  50.665  -91.608 1.00 22.43  ? 324 TYR A1 CD2 1 
ATOM 2285 C CE1 . TYR A 1 324 ? 72.391  48.791  -92.867 1.00 25.15  ? 324 TYR A1 CE1 1 
ATOM 2286 C CE2 . TYR A 1 324 ? 71.481  50.999  -92.762 1.00 25.18  ? 324 TYR A1 CE2 1 
ATOM 2287 C CZ  . TYR A 1 324 ? 72.265  50.056  -93.388 1.00 26.83  ? 324 TYR A1 CZ  1 
ATOM 2288 O OH  . TYR A 1 324 ? 72.927  50.389  -94.542 1.00 30.38  ? 324 TYR A1 OH  1 
ATOM 2289 N N   . ILE A 1 325 ? 68.748  46.216  -88.485 1.00 11.52  ? 325 ILE A1 N   1 
ATOM 2290 C CA  . ILE A 1 325 ? 68.506  45.616  -87.182 1.00 10.44  ? 325 ILE A1 CA  1 
ATOM 2291 C C   . ILE A 1 325 ? 69.818  45.029  -86.694 1.00 11.21  ? 325 ILE A1 C   1 
ATOM 2292 O O   . ILE A 1 325 ? 70.146  43.878  -86.991 1.00 12.37  ? 325 ILE A1 O   1 
ATOM 2293 C CB  . ILE A 1 325 ? 67.400  44.551  -87.235 1.00 8.76   ? 325 ILE A1 CB  1 
ATOM 2294 C CG1 . ILE A 1 325 ? 66.171  45.096  -87.951 1.00 8.10   ? 325 ILE A1 CG1 1 
ATOM 2295 C CG2 . ILE A 1 325 ? 67.023  44.141  -85.845 1.00 7.68   ? 325 ILE A1 CG2 1 
ATOM 2296 C CD1 . ILE A 1 325 ? 65.003  44.160  -87.972 1.00 8.52   ? 325 ILE A1 CD1 1 
ATOM 2297 N N   . THR A 1 326 ? 70.580  45.814  -85.955 1.00 9.83   ? 326 THR A1 N   1 
ATOM 2298 C CA  . THR A 1 326 ? 71.850  45.376  -85.416 1.00 8.01   ? 326 THR A1 CA  1 
ATOM 2299 C C   . THR A 1 326 ? 71.681  45.087  -83.933 1.00 8.98   ? 326 THR A1 C   1 
ATOM 2300 O O   . THR A 1 326 ? 70.578  45.151  -83.388 1.00 8.55   ? 326 THR A1 O   1 
ATOM 2301 C CB  . THR A 1 326 ? 72.930  46.422  -85.669 1.00 6.67   ? 326 THR A1 CB  1 
ATOM 2302 O OG1 . THR A 1 326 ? 72.641  47.599  -84.912 1.00 6.33   ? 326 THR A1 OG1 1 
ATOM 2303 C CG2 . THR A 1 326 ? 72.962  46.791  -87.123 1.00 7.08   ? 326 THR A1 CG2 1 
ATOM 2304 N N   . GLU A 1 327 ? 72.788  44.768  -83.273 1.00 8.48   ? 327 GLU A1 N   1 
ATOM 2305 C CA  . GLU A 1 327 ? 72.735  44.499  -81.847 1.00 9.61   ? 327 GLU A1 CA  1 
ATOM 2306 C C   . GLU A 1 327 ? 72.603  45.772  -81.031 1.00 11.88  ? 327 GLU A1 C   1 
ATOM 2307 O O   . GLU A 1 327 ? 72.134  45.718  -79.892 1.00 15.44  ? 327 GLU A1 O   1 
ATOM 2308 C CB  . GLU A 1 327 ? 73.979  43.733  -81.420 1.00 11.27  ? 327 GLU A1 CB  1 
ATOM 2309 C CG  . GLU A 1 327 ? 73.846  42.239  -81.536 1.00 13.65  ? 327 GLU A1 CG  1 
ATOM 2310 C CD  . GLU A 1 327 ? 73.121  41.647  -80.360 1.00 14.61  ? 327 GLU A1 CD  1 
ATOM 2311 O OE1 . GLU A 1 327 ? 73.718  41.601  -79.266 1.00 15.22  ? 327 GLU A1 OE1 1 
ATOM 2312 O OE2 . GLU A 1 327 ? 71.961  41.224  -80.524 1.00 14.41  ? 327 GLU A1 OE2 1 
ATOM 2313 N N   . ALA A 1 328 ? 72.998  46.909  -81.590 1.00 11.93  ? 328 ALA A1 N   1 
ATOM 2314 C CA  . ALA A 1 328 ? 72.907  48.176  -80.885 1.00 9.70   ? 328 ALA A1 CA  1 
ATOM 2315 C C   . ALA A 1 328 ? 71.537  48.823  -81.002 1.00 9.27   ? 328 ALA A1 C   1 
ATOM 2316 O O   . ALA A 1 328 ? 71.142  49.563  -80.100 1.00 9.08   ? 328 ALA A1 O   1 
ATOM 2317 C CB  . ALA A 1 328 ? 73.973  49.132  -81.411 1.00 10.56  ? 328 ALA A1 CB  1 
ATOM 2318 N N   . THR A 1 329 ? 70.800  48.561  -82.076 1.00 8.18   ? 329 THR A1 N   1 
ATOM 2319 C CA  . THR A 1 329 ? 69.541  49.239  -82.332 1.00 6.29   ? 329 THR A1 CA  1 
ATOM 2320 C C   . THR A 1 329 ? 68.314  48.366  -82.122 1.00 7.97   ? 329 THR A1 C   1 
ATOM 2321 O O   . THR A 1 329 ? 67.197  48.869  -82.273 1.00 10.63  ? 329 THR A1 O   1 
ATOM 2322 C CB  . THR A 1 329 ? 69.517  49.780  -83.765 1.00 5.05   ? 329 THR A1 CB  1 
ATOM 2323 O OG1 . THR A 1 329 ? 69.600  48.686  -84.678 1.00 5.79   ? 329 THR A1 OG1 1 
ATOM 2324 C CG2 . THR A 1 329 ? 70.713  50.660  -83.993 1.00 3.33   ? 329 THR A1 CG2 1 
ATOM 2325 N N   . ILE A 1 330 ? 68.486  47.081  -81.800 1.00 8.37   ? 330 ILE A1 N   1 
ATOM 2326 C CA  . ILE A 1 330 ? 67.358  46.207  -81.516 1.00 6.80   ? 330 ILE A1 CA  1 
ATOM 2327 C C   . ILE A 1 330 ? 66.652  46.676  -80.242 1.00 7.31   ? 330 ILE A1 C   1 
ATOM 2328 O O   . ILE A 1 330 ? 67.277  47.196  -79.313 1.00 6.90   ? 330 ILE A1 O   1 
ATOM 2329 C CB  . ILE A 1 330 ? 67.859  44.753  -81.414 1.00 4.60   ? 330 ILE A1 CB  1 
ATOM 2330 C CG1 . ILE A 1 330 ? 66.738  43.745  -81.162 1.00 2.32   ? 330 ILE A1 CG1 1 
ATOM 2331 C CG2 . ILE A 1 330 ? 68.946  44.619  -80.392 1.00 4.29   ? 330 ILE A1 CG2 1 
ATOM 2332 C CD1 . ILE A 1 330 ? 65.937  43.408  -82.369 1.00 2.53   ? 330 ILE A1 CD1 1 
ATOM 2333 N N   . MET A 1 331 ? 65.325  46.555  -80.228 1.00 6.85   ? 331 MET A1 N   1 
ATOM 2334 C CA  . MET A 1 331 ? 64.513  47.077  -79.138 1.00 5.99   ? 331 MET A1 CA  1 
ATOM 2335 C C   . MET A 1 331 ? 64.550  46.107  -77.966 1.00 7.16   ? 331 MET A1 C   1 
ATOM 2336 O O   . MET A 1 331 ? 64.266  44.917  -78.128 1.00 10.02  ? 331 MET A1 O   1 
ATOM 2337 C CB  . MET A 1 331 ? 63.077  47.318  -79.590 1.00 4.86   ? 331 MET A1 CB  1 
ATOM 2338 C CG  . MET A 1 331 ? 62.123  47.690  -78.468 1.00 5.30   ? 331 MET A1 CG  1 
ATOM 2339 S SD  . MET A 1 331 ? 60.394  47.435  -78.886 1.00 8.84   ? 331 MET A1 SD  1 
ATOM 2340 C CE  . MET A 1 331 ? 60.059  48.915  -79.823 1.00 6.84   ? 331 MET A1 CE  1 
ATOM 2341 N N   . ARG A 1 332 ? 64.898  46.615  -76.803 1.00 7.47   ? 332 ARG A1 N   1 
ATOM 2342 C CA  . ARG A 1 332 ? 65.052  46.155  -75.435 1.00 7.74   ? 332 ARG A1 CA  1 
ATOM 2343 C C   . ARG A 1 332 ? 63.815  46.511  -74.614 1.00 8.62   ? 332 ARG A1 C   1 
ATOM 2344 O O   . ARG A 1 332 ? 63.093  47.451  -74.957 1.00 11.39  ? 332 ARG A1 O   1 
ATOM 2345 C CB  . ARG A 1 332 ? 66.288  46.790  -74.817 1.00 7.01   ? 332 ARG A1 CB  1 
ATOM 2346 C CG  . ARG A 1 332 ? 67.536  46.553  -75.617 1.00 6.54   ? 332 ARG A1 CG  1 
ATOM 2347 C CD  . ARG A 1 332 ? 67.806  45.084  -75.815 1.00 6.57   ? 332 ARG A1 CD  1 
ATOM 2348 N NE  . ARG A 1 332 ? 69.059  44.886  -76.529 1.00 7.53   ? 332 ARG A1 NE  1 
ATOM 2349 C CZ  . ARG A 1 332 ? 69.482  43.718  -76.985 1.00 8.09   ? 332 ARG A1 CZ  1 
ATOM 2350 N NH1 . ARG A 1 332 ? 68.751  42.633  -76.808 1.00 6.99   ? 332 ARG A1 NH1 1 
ATOM 2351 N NH2 . ARG A 1 332 ? 70.638  43.638  -77.617 1.00 8.40   ? 332 ARG A1 NH2 1 
ATOM 2352 N N   . PRO A 1 333 ? 63.514  45.777  -73.535 1.00 7.27   ? 333 PRO A1 N   1 
ATOM 2353 C CA  . PRO A 1 333 ? 62.313  46.106  -72.758 1.00 7.44   ? 333 PRO A1 CA  1 
ATOM 2354 C C   . PRO A 1 333 ? 62.439  47.387  -71.959 1.00 7.85   ? 333 PRO A1 C   1 
ATOM 2355 O O   . PRO A 1 333 ? 61.443  48.096  -71.781 1.00 9.41   ? 333 PRO A1 O   1 
ATOM 2356 C CB  . PRO A 1 333 ? 62.150  44.895  -71.834 1.00 7.12   ? 333 PRO A1 CB  1 
ATOM 2357 C CG  . PRO A 1 333 ? 63.014  43.844  -72.401 1.00 6.56   ? 333 PRO A1 CG  1 
ATOM 2358 C CD  . PRO A 1 333 ? 64.141  44.542  -73.040 1.00 7.30   ? 333 PRO A1 CD  1 
ATOM 2359 N N   . ALA A 1 334 ? 63.628  47.710  -71.477 1.00 6.52   ? 334 ALA A1 N   1 
ATOM 2360 C CA  . ALA A 1 334 ? 63.835  48.863  -70.620 1.00 6.22   ? 334 ALA A1 CA  1 
ATOM 2361 C C   . ALA A 1 334 ? 65.238  49.386  -70.877 1.00 6.66   ? 334 ALA A1 C   1 
ATOM 2362 O O   . ALA A 1 334 ? 65.855  49.073  -71.898 1.00 8.23   ? 334 ALA A1 O   1 
ATOM 2363 C CB  . ALA A 1 334 ? 63.621  48.497  -69.152 1.00 5.34   ? 334 ALA A1 CB  1 
ATOM 2364 N N   . GLU A 1 335 ? 65.740  50.195  -69.952 1.00 7.61   ? 335 GLU A1 N   1 
ATOM 2365 C CA  . GLU A 1 335 ? 67.096  50.716  -69.998 1.00 6.47   ? 335 GLU A1 CA  1 
ATOM 2366 C C   . GLU A 1 335 ? 67.739  50.461  -68.648 1.00 5.57   ? 335 GLU A1 C   1 
ATOM 2367 O O   . GLU A 1 335 ? 67.096  50.631  -67.613 1.00 3.78   ? 335 GLU A1 O   1 
ATOM 2368 C CB  . GLU A 1 335 ? 67.103  52.206  -70.324 1.00 6.43   ? 335 GLU A1 CB  1 
ATOM 2369 C CG  . GLU A 1 335 ? 68.468  52.766  -70.625 1.00 8.97   ? 335 GLU A1 CG  1 
ATOM 2370 C CD  . GLU A 1 335 ? 68.477  54.275  -70.644 1.00 11.47  ? 335 GLU A1 CD  1 
ATOM 2371 O OE1 . GLU A 1 335 ? 67.426  54.880  -70.358 1.00 12.51  ? 335 GLU A1 OE1 1 
ATOM 2372 O OE2 . GLU A 1 335 ? 69.538  54.858  -70.942 1.00 12.95  ? 335 GLU A1 OE2 1 
ATOM 2373 N N   . VAL A 1 336 ? 68.992  50.033  -68.655 1.00 5.96   ? 336 VAL A1 N   1 
ATOM 2374 C CA  . VAL A 1 336 ? 69.675  49.612  -67.440 1.00 7.67   ? 336 VAL A1 CA  1 
ATOM 2375 C C   . VAL A 1 336 ? 70.694  50.672  -67.066 1.00 10.17  ? 336 VAL A1 C   1 
ATOM 2376 O O   . VAL A 1 336 ? 71.657  50.909  -67.804 1.00 11.32  ? 336 VAL A1 O   1 
ATOM 2377 C CB  . VAL A 1 336 ? 70.336  48.244  -67.623 1.00 6.68   ? 336 VAL A1 CB  1 
ATOM 2378 C CG1 . VAL A 1 336 ? 70.960  47.793  -66.331 1.00 6.72   ? 336 VAL A1 CG1 1 
ATOM 2379 C CG2 . VAL A 1 336 ? 69.307  47.255  -68.094 1.00 7.01   ? 336 VAL A1 CG2 1 
ATOM 2380 N N   . GLY A 1 337 ? 70.486  51.310  -65.926 1.00 10.34  ? 337 GLY A1 N   1 
ATOM 2381 C CA  . GLY A 1 337 ? 71.310  52.428  -65.540 1.00 10.24  ? 337 GLY A1 CA  1 
ATOM 2382 C C   . GLY A 1 337 ? 70.882  53.677  -66.273 1.00 10.40  ? 337 GLY A1 C   1 
ATOM 2383 O O   . GLY A 1 337 ? 69.930  53.691  -67.047 1.00 12.06  ? 337 GLY A1 O   1 
ATOM 2384 N N   . TYR A 1 338 ? 71.609  54.755  -66.015 1.00 9.37   ? 338 TYR A1 N   1 
ATOM 2385 C CA  . TYR A 1 338 ? 71.280  56.032  -66.626 1.00 8.65   ? 338 TYR A1 CA  1 
ATOM 2386 C C   . TYR A 1 338 ? 72.536  56.878  -66.677 1.00 10.13  ? 338 TYR A1 C   1 
ATOM 2387 O O   . TYR A 1 338 ? 73.513  56.609  -65.980 1.00 12.20  ? 338 TYR A1 O   1 
ATOM 2388 C CB  . TYR A 1 338 ? 70.160  56.749  -65.863 1.00 7.27   ? 338 TYR A1 CB  1 
ATOM 2389 C CG  . TYR A 1 338 ? 70.571  57.432  -64.580 1.00 5.70   ? 338 TYR A1 CG  1 
ATOM 2390 C CD1 . TYR A 1 338 ? 71.002  56.703  -63.485 1.00 6.85   ? 338 TYR A1 CD1 1 
ATOM 2391 C CD2 . TYR A 1 338 ? 70.494  58.806  -64.458 1.00 5.40   ? 338 TYR A1 CD2 1 
ATOM 2392 C CE1 . TYR A 1 338 ? 71.369  57.324  -62.320 1.00 6.61   ? 338 TYR A1 CE1 1 
ATOM 2393 C CE2 . TYR A 1 338 ? 70.858  59.437  -63.293 1.00 5.29   ? 338 TYR A1 CE2 1 
ATOM 2394 C CZ  . TYR A 1 338 ? 71.293  58.690  -62.229 1.00 5.75   ? 338 TYR A1 CZ  1 
ATOM 2395 O OH  . TYR A 1 338 ? 71.653  59.321  -61.066 1.00 4.74   ? 338 TYR A1 OH  1 
ATOM 2396 N N   . SER A 1 339 ? 72.507  57.892  -67.532 1.00 11.08  ? 339 SER A1 N   1 
ATOM 2397 C CA  . SER A 1 339 ? 73.597  58.848  -67.606 1.00 8.57   ? 339 SER A1 CA  1 
ATOM 2398 C C   . SER A 1 339 ? 73.258  60.060  -66.765 1.00 8.54   ? 339 SER A1 C   1 
ATOM 2399 O O   . SER A 1 339 ? 72.112  60.504  -66.728 1.00 9.03   ? 339 SER A1 O   1 
ATOM 2400 C CB  . SER A 1 339 ? 73.864  59.279  -69.044 1.00 7.06   ? 339 SER A1 CB  1 
ATOM 2401 O OG  . SER A 1 339 ? 73.907  58.163  -69.907 1.00 2.93   ? 339 SER A1 OG  1 
ATOM 2402 N N   . ALA A 1 340 ? 74.260  60.593  -66.094 1.00 8.34   ? 340 ALA A1 N   1 
ATOM 2403 C CA  . ALA A 1 340 ? 74.068  61.766  -65.270 1.00 8.27   ? 340 ALA A1 CA  1 
ATOM 2404 C C   . ALA A 1 340 ? 75.169  62.770  -65.564 1.00 8.19   ? 340 ALA A1 C   1 
ATOM 2405 O O   . ALA A 1 340 ? 76.251  62.384  -66.015 1.00 8.96   ? 340 ALA A1 O   1 
ATOM 2406 C CB  . ALA A 1 340 ? 74.079  61.379  -63.790 1.00 7.15   ? 340 ALA A1 CB  1 
ATOM 2407 N N   . PRO A 1 341 ? 74.910  64.064  -65.368 1.00 6.81   ? 341 PRO A1 N   1 
ATOM 2408 C CA  . PRO A 1 341 ? 75.975  65.061  -65.549 1.00 7.76   ? 341 PRO A1 CA  1 
ATOM 2409 C C   . PRO A 1 341 ? 77.044  64.908  -64.479 1.00 10.02  ? 341 PRO A1 C   1 
ATOM 2410 O O   . PRO A 1 341 ? 76.772  65.093  -63.294 1.00 11.84  ? 341 PRO A1 O   1 
ATOM 2411 C CB  . PRO A 1 341 ? 75.232  66.395  -65.416 1.00 5.93   ? 341 PRO A1 CB  1 
ATOM 2412 C CG  . PRO A 1 341 ? 73.826  66.076  -65.720 1.00 6.09   ? 341 PRO A1 CG  1 
ATOM 2413 C CD  . PRO A 1 341 ? 73.593  64.702  -65.215 1.00 5.86   ? 341 PRO A1 CD  1 
ATOM 2414 N N   . TYR A 1 342 ? 78.261  64.559  -64.890 1.00 10.58  ? 342 TYR A1 N   1 
ATOM 2415 C CA  . TYR A 1 342 ? 79.291  64.241  -63.915 1.00 11.22  ? 342 TYR A1 CA  1 
ATOM 2416 C C   . TYR A 1 342 ? 80.175  65.442  -63.615 1.00 12.77  ? 342 TYR A1 C   1 
ATOM 2417 O O   . TYR A 1 342 ? 80.545  66.210  -64.509 1.00 13.12  ? 342 TYR A1 O   1 
ATOM 2418 C CB  . TYR A 1 342 ? 80.149  63.038  -64.317 1.00 10.14  ? 342 TYR A1 CB  1 
ATOM 2419 C CG  . TYR A 1 342 ? 80.662  62.939  -65.722 1.00 10.90  ? 342 TYR A1 CG  1 
ATOM 2420 C CD1 . TYR A 1 342 ? 79.920  62.306  -66.701 1.00 11.47  ? 342 TYR A1 CD1 1 
ATOM 2421 C CD2 . TYR A 1 342 ? 81.929  63.383  -66.047 1.00 11.46  ? 342 TYR A1 CD2 1 
ATOM 2422 C CE1 . TYR A 1 342 ? 80.400  62.172  -67.979 1.00 12.50  ? 342 TYR A1 CE1 1 
ATOM 2423 C CE2 . TYR A 1 342 ? 82.418  63.253  -67.325 1.00 13.13  ? 342 TYR A1 CE2 1 
ATOM 2424 C CZ  . TYR A 1 342 ? 81.647  62.646  -68.286 1.00 13.49  ? 342 TYR A1 CZ  1 
ATOM 2425 O OH  . TYR A 1 342 ? 82.131  62.517  -69.562 1.00 16.89  ? 342 TYR A1 OH  1 
ATOM 2426 N N   . TYR A 1 343 ? 80.508  65.549  -62.326 1.00 13.31  ? 343 TYR A1 N   1 
ATOM 2427 C CA  . TYR A 1 343 ? 81.111  66.712  -61.680 1.00 13.40  ? 343 TYR A1 CA  1 
ATOM 2428 C C   . TYR A 1 343 ? 80.318  67.974  -61.988 1.00 13.05  ? 343 TYR A1 C   1 
ATOM 2429 O O   . TYR A 1 343 ? 80.863  69.020  -62.333 1.00 15.52  ? 343 TYR A1 O   1 
ATOM 2430 C CB  . TYR A 1 343 ? 82.584  66.862  -62.044 1.00 15.46  ? 343 TYR A1 CB  1 
ATOM 2431 C CG  . TYR A 1 343 ? 83.467  65.791  -61.439 1.00 18.11  ? 343 TYR A1 CG  1 
ATOM 2432 C CD1 . TYR A 1 343 ? 82.997  64.936  -60.449 1.00 18.54  ? 343 TYR A1 CD1 1 
ATOM 2433 C CD2 . TYR A 1 343 ? 84.775  65.640  -61.854 1.00 20.20  ? 343 TYR A1 CD2 1 
ATOM 2434 C CE1 . TYR A 1 343 ? 83.795  63.959  -59.912 1.00 19.71  ? 343 TYR A1 CE1 1 
ATOM 2435 C CE2 . TYR A 1 343 ? 85.583  64.666  -61.313 1.00 20.53  ? 343 TYR A1 CE2 1 
ATOM 2436 C CZ  . TYR A 1 343 ? 85.089  63.831  -60.343 1.00 19.89  ? 343 TYR A1 CZ  1 
ATOM 2437 O OH  . TYR A 1 343 ? 85.903  62.865  -59.809 1.00 19.65  ? 343 TYR A1 OH  1 
ATOM 2438 N N   . SER A 1 344 ? 79.005  67.863  -61.841 1.00 10.99  ? 344 SER A1 N   1 
ATOM 2439 C CA  . SER A 1 344 ? 78.098  68.989  -61.969 1.00 9.93   ? 344 SER A1 CA  1 
ATOM 2440 C C   . SER A 1 344 ? 77.822  69.507  -60.573 1.00 10.10  ? 344 SER A1 C   1 
ATOM 2441 O O   . SER A 1 344 ? 77.387  68.746  -59.706 1.00 10.19  ? 344 SER A1 O   1 
ATOM 2442 C CB  . SER A 1 344 ? 76.797  68.585  -62.652 1.00 9.76   ? 344 SER A1 CB  1 
ATOM 2443 O OG  . SER A 1 344 ? 75.848  68.160  -61.697 1.00 10.50  ? 344 SER A1 OG  1 
ATOM 2444 N N   . PHE A 1 345 ? 78.077  70.787  -60.357 1.00 9.19   ? 345 PHE A1 N   1 
ATOM 2445 C CA  . PHE A 1 345 ? 77.914  71.402  -59.050 1.00 7.37   ? 345 PHE A1 CA  1 
ATOM 2446 C C   . PHE A 1 345 ? 76.698  72.313  -59.095 1.00 7.02   ? 345 PHE A1 C   1 
ATOM 2447 O O   . PHE A 1 345 ? 76.763  73.425  -59.615 1.00 8.17   ? 345 PHE A1 O   1 
ATOM 2448 C CB  . PHE A 1 345 ? 79.172  72.163  -58.656 1.00 7.76   ? 345 PHE A1 CB  1 
ATOM 2449 C CG  . PHE A 1 345 ? 80.283  71.285  -58.171 1.00 8.54   ? 345 PHE A1 CG  1 
ATOM 2450 C CD1 . PHE A 1 345 ? 81.135  70.668  -59.065 1.00 8.67   ? 345 PHE A1 CD1 1 
ATOM 2451 C CD2 . PHE A 1 345 ? 80.476  71.079  -56.823 1.00 8.62   ? 345 PHE A1 CD2 1 
ATOM 2452 C CE1 . PHE A 1 345 ? 82.154  69.866  -58.621 1.00 8.91   ? 345 PHE A1 CE1 1 
ATOM 2453 C CE2 . PHE A 1 345 ? 81.490  70.274  -56.375 1.00 9.22   ? 345 PHE A1 CE2 1 
ATOM 2454 C CZ  . PHE A 1 345 ? 82.328  69.667  -57.276 1.00 9.91   ? 345 PHE A1 CZ  1 
ATOM 2455 N N   . GLU A 1 346 ? 75.586  71.836  -58.552 1.00 6.17   ? 346 GLU A1 N   1 
ATOM 2456 C CA  . GLU A 1 346 ? 74.408  72.669  -58.415 1.00 4.12   ? 346 GLU A1 CA  1 
ATOM 2457 C C   . GLU A 1 346 ? 74.579  73.634  -57.253 1.00 3.52   ? 346 GLU A1 C   1 
ATOM 2458 O O   . GLU A 1 346 ? 75.495  73.512  -56.447 1.00 3.59   ? 346 GLU A1 O   1 
ATOM 2459 C CB  . GLU A 1 346 ? 73.164  71.817  -58.197 1.00 4.37   ? 346 GLU A1 CB  1 
ATOM 2460 C CG  . GLU A 1 346 ? 72.623  71.175  -59.444 1.00 5.19   ? 346 GLU A1 CG  1 
ATOM 2461 C CD  . GLU A 1 346 ? 71.213  70.656  -59.258 1.00 8.04   ? 346 GLU A1 CD  1 
ATOM 2462 O OE1 . GLU A 1 346 ? 70.850  69.674  -59.939 1.00 9.83   ? 346 GLU A1 OE1 1 
ATOM 2463 O OE2 . GLU A 1 346 ? 70.470  71.225  -58.427 1.00 9.08   ? 346 GLU A1 OE2 1 
ATOM 2464 N N   . ALA A 1 347 ? 73.686  74.610  -57.185 1.00 2.73   ? 347 ALA A1 N   1 
ATOM 2465 C CA  . ALA A 1 347 ? 73.685  75.599  -56.124 1.00 3.27   ? 347 ALA A1 CA  1 
ATOM 2466 C C   . ALA A 1 347 ? 72.274  75.753  -55.589 1.00 6.34   ? 347 ALA A1 C   1 
ATOM 2467 O O   . ALA A 1 347 ? 71.299  75.335  -56.211 1.00 6.42   ? 347 ALA A1 O   1 
ATOM 2468 C CB  . ALA A 1 347 ? 74.217  76.946  -56.616 1.00 2.72   ? 347 ALA A1 CB  1 
ATOM 2469 N N   . SER A 1 348 ? 72.176  76.369  -54.421 1.00 9.26   ? 348 SER A1 N   1 
ATOM 2470 C CA  . SER A 1 348 ? 70.909  76.510  -53.728 1.00 12.36  ? 348 SER A1 CA  1 
ATOM 2471 C C   . SER A 1 348 ? 71.038  77.683  -52.768 1.00 14.65  ? 348 SER A1 C   1 
ATOM 2472 O O   . SER A 1 348 ? 71.873  78.571  -52.977 1.00 20.08  ? 348 SER A1 O   1 
ATOM 2473 C CB  . SER A 1 348 ? 70.515  75.202  -53.030 1.00 12.62  ? 348 SER A1 CB  1 
ATOM 2474 O OG  . SER A 1 348 ? 69.125  75.191  -52.769 1.00 13.79  ? 348 SER A1 OG  1 
ATOM 2475 N N   . THR A 1 349 ? 70.172  77.708  -51.752 1.00 14.12  ? 349 THR A1 N   1 
ATOM 2476 C CA  . THR A 1 349 ? 70.121  78.805  -50.787 1.00 12.30  ? 349 THR A1 CA  1 
ATOM 2477 C C   . THR A 1 349 ? 71.438  78.986  -50.041 1.00 12.39  ? 349 THR A1 C   1 
ATOM 2478 O O   . THR A 1 349 ? 71.777  80.099  -49.630 1.00 12.10  ? 349 THR A1 O   1 
ATOM 2479 C CB  . THR A 1 349 ? 68.997  78.548  -49.785 1.00 12.38  ? 349 THR A1 CB  1 
ATOM 2480 O OG1 . THR A 1 349 ? 67.883  77.958  -50.460 1.00 14.94  ? 349 THR A1 OG1 1 
ATOM 2481 C CG2 . THR A 1 349 ? 68.540  79.841  -49.144 1.00 15.14  ? 349 THR A1 CG2 1 
ATOM 2482 N N   . GLN A 1 350 ? 72.198  77.914  -49.860 1.00 14.28  ? 350 GLN A1 N   1 
ATOM 2483 C CA  . GLN A 1 350 ? 73.290  77.909  -48.903 1.00 13.44  ? 350 GLN A1 CA  1 
ATOM 2484 C C   . GLN A 1 350 ? 74.555  77.279  -49.464 1.00 11.53  ? 350 GLN A1 C   1 
ATOM 2485 O O   . GLN A 1 350 ? 75.279  76.569  -48.771 1.00 10.05  ? 350 GLN A1 O   1 
ATOM 2486 C CB  . GLN A 1 350 ? 72.822  77.236  -47.620 1.00 16.17  ? 350 GLN A1 CB  1 
ATOM 2487 C CG  . GLN A 1 350 ? 72.273  75.853  -47.786 1.00 18.79  ? 350 GLN A1 CG  1 
ATOM 2488 C CD  . GLN A 1 350 ? 71.386  75.472  -46.638 1.00 20.45  ? 350 GLN A1 CD  1 
ATOM 2489 O OE1 . GLN A 1 350 ? 71.173  76.251  -45.721 1.00 24.05  ? 350 GLN A1 OE1 1 
ATOM 2490 N NE2 . GLN A 1 350 ? 70.838  74.274  -46.695 1.00 22.36  ? 350 GLN A1 NE2 1 
ATOM 2491 N N   . GLY A 1 351 ? 74.857  77.567  -50.721 1.00 10.21  ? 351 GLY A1 N   1 
ATOM 2492 C CA  . GLY A 1 351 ? 76.134  77.224  -51.289 1.00 10.52  ? 351 GLY A1 CA  1 
ATOM 2493 C C   . GLY A 1 351 ? 76.067  76.104  -52.298 1.00 10.54  ? 351 GLY A1 C   1 
ATOM 2494 O O   . GLY A 1 351 ? 75.051  75.418  -52.438 1.00 12.69  ? 351 GLY A1 O   1 
ATOM 2495 N N   . PRO A 1 352 ? 77.162  75.897  -53.023 1.00 9.19   ? 352 PRO A1 N   1 
ATOM 2496 C CA  . PRO A 1 352 ? 77.198  74.833  -54.028 1.00 8.83   ? 352 PRO A1 CA  1 
ATOM 2497 C C   . PRO A 1 352 ? 77.341  73.451  -53.419 1.00 8.01   ? 352 PRO A1 C   1 
ATOM 2498 O O   . PRO A 1 352 ? 77.850  73.287  -52.310 1.00 7.08   ? 352 PRO A1 O   1 
ATOM 2499 C CB  . PRO A 1 352 ? 78.434  75.187  -54.860 1.00 9.98   ? 352 PRO A1 CB  1 
ATOM 2500 C CG  . PRO A 1 352 ? 79.284  75.941  -53.935 1.00 9.43   ? 352 PRO A1 CG  1 
ATOM 2501 C CD  . PRO A 1 352 ? 78.355  76.752  -53.102 1.00 8.88   ? 352 PRO A1 CD  1 
ATOM 2502 N N   . PHE A 1 353 ? 76.889  72.451  -54.167 1.00 7.22   ? 353 PHE A1 N   1 
ATOM 2503 C CA  . PHE A 1 353 ? 77.048  71.056  -53.790 1.00 6.63   ? 353 PHE A1 CA  1 
ATOM 2504 C C   . PHE A 1 353 ? 77.092  70.206  -55.045 1.00 5.38   ? 353 PHE A1 C   1 
ATOM 2505 O O   . PHE A 1 353 ? 76.689  70.641  -56.119 1.00 5.09   ? 353 PHE A1 O   1 
ATOM 2506 C CB  . PHE A 1 353 ? 75.926  70.577  -52.861 1.00 7.75   ? 353 PHE A1 CB  1 
ATOM 2507 C CG  . PHE A 1 353 ? 74.534  70.853  -53.363 1.00 8.14   ? 353 PHE A1 CG  1 
ATOM 2508 C CD1 . PHE A 1 353 ? 73.870  69.940  -54.160 1.00 9.39   ? 353 PHE A1 CD1 1 
ATOM 2509 C CD2 . PHE A 1 353 ? 73.872  72.003  -52.988 1.00 7.20   ? 353 PHE A1 CD2 1 
ATOM 2510 C CE1 . PHE A 1 353 ? 72.598  70.185  -54.593 1.00 9.44   ? 353 PHE A1 CE1 1 
ATOM 2511 C CE2 . PHE A 1 353 ? 72.599  72.247  -53.416 1.00 7.33   ? 353 PHE A1 CE2 1 
ATOM 2512 C CZ  . PHE A 1 353 ? 71.963  71.337  -54.220 1.00 8.91   ? 353 PHE A1 CZ  1 
ATOM 2513 N N   . LYS A 1 354 ? 77.571  68.980  -54.903 1.00 4.73   ? 354 LYS A1 N   1 
ATOM 2514 C CA  . LYS A 1 354 ? 77.692  68.073  -56.032 1.00 5.63   ? 354 LYS A1 CA  1 
ATOM 2515 C C   . LYS A 1 354 ? 76.451  67.197  -56.126 1.00 7.24   ? 354 LYS A1 C   1 
ATOM 2516 O O   . LYS A 1 354 ? 75.958  66.700  -55.110 1.00 8.24   ? 354 LYS A1 O   1 
ATOM 2517 C CB  . LYS A 1 354 ? 78.945  67.214  -55.885 1.00 4.88   ? 354 LYS A1 CB  1 
ATOM 2518 C CG  . LYS A 1 354 ? 79.240  66.347  -57.075 1.00 6.42   ? 354 LYS A1 CG  1 
ATOM 2519 C CD  . LYS A 1 354 ? 80.499  65.557  -56.860 1.00 6.69   ? 354 LYS A1 CD  1 
ATOM 2520 C CE  . LYS A 1 354 ? 80.535  64.341  -57.761 1.00 7.24   ? 354 LYS A1 CE  1 
ATOM 2521 N NZ  . LYS A 1 354 ? 79.463  63.365  -57.427 1.00 8.12   ? 354 LYS A1 NZ  1 
ATOM 2522 N N   . THR A 1 355 ? 75.942  67.015  -57.341 1.00 7.83   ? 355 THR A1 N   1 
ATOM 2523 C CA  . THR A 1 355 ? 74.796  66.132  -57.506 1.00 8.47   ? 355 THR A1 CA  1 
ATOM 2524 C C   . THR A 1 355 ? 75.232  64.678  -57.371 1.00 9.83   ? 355 THR A1 C   1 
ATOM 2525 O O   . THR A 1 355 ? 76.187  64.257  -58.025 1.00 12.16  ? 355 THR A1 O   1 
ATOM 2526 C CB  . THR A 1 355 ? 74.148  66.327  -58.862 1.00 7.46   ? 355 THR A1 CB  1 
ATOM 2527 O OG1 . THR A 1 355 ? 75.068  65.932  -59.882 1.00 9.12   ? 355 THR A1 OG1 1 
ATOM 2528 C CG2 . THR A 1 355 ? 73.799  67.758  -59.055 1.00 7.12   ? 355 THR A1 CG2 1 
ATOM 2529 N N   . PRO A 1 356 ? 74.544  63.892  -56.548 1.00 10.48  ? 356 PRO A1 N   1 
ATOM 2530 C CA  . PRO A 1 356 ? 74.972  62.511  -56.323 1.00 10.16  ? 356 PRO A1 CA  1 
ATOM 2531 C C   . PRO A 1 356 ? 74.641  61.619  -57.506 1.00 10.03  ? 356 PRO A1 C   1 
ATOM 2532 O O   . PRO A 1 356 ? 73.732  61.894  -58.288 1.00 10.08  ? 356 PRO A1 O   1 
ATOM 2533 C CB  . PRO A 1 356 ? 74.180  62.097  -55.078 1.00 8.62   ? 356 PRO A1 CB  1 
ATOM 2534 C CG  . PRO A 1 356 ? 73.648  63.373  -54.508 1.00 8.49   ? 356 PRO A1 CG  1 
ATOM 2535 C CD  . PRO A 1 356 ? 73.426  64.256  -55.671 1.00 9.53   ? 356 PRO A1 CD  1 
ATOM 2536 N N   . ILE A 1 357 ? 75.411  60.542  -57.637 1.00 12.45  ? 357 ILE A1 N   1 
ATOM 2537 C CA  . ILE A 1 357 ? 75.316  59.616  -58.757 1.00 13.92  ? 357 ILE A1 CA  1 
ATOM 2538 C C   . ILE A 1 357 ? 75.147  58.214  -58.195 1.00 14.99  ? 357 ILE A1 C   1 
ATOM 2539 O O   . ILE A 1 357 ? 75.792  57.846  -57.209 1.00 13.72  ? 357 ILE A1 O   1 
ATOM 2540 C CB  . ILE A 1 357 ? 76.572  59.656  -59.665 1.00 14.34  ? 357 ILE A1 CB  1 
ATOM 2541 C CG1 . ILE A 1 357 ? 77.020  61.084  -59.962 1.00 17.79  ? 357 ILE A1 CG1 1 
ATOM 2542 C CG2 . ILE A 1 357 ? 76.325  58.929  -60.972 1.00 12.16  ? 357 ILE A1 CG2 1 
ATOM 2543 C CD1 . ILE A 1 357 ? 76.040  61.882  -60.759 1.00 22.83  ? 357 ILE A1 CD1 1 
ATOM 2544 N N   . ALA A 1 358 ? 74.261  57.431  -58.807 1.00 16.65  ? 358 ALA A1 N   1 
ATOM 2545 C CA  . ALA A 1 358 ? 74.296  55.989  -58.594 1.00 18.12  ? 358 ALA A1 CA  1 
ATOM 2546 C C   . ALA A 1 358 ? 74.913  55.293  -59.803 1.00 21.25  ? 358 ALA A1 C   1 
ATOM 2547 O O   . ALA A 1 358 ? 74.275  55.208  -60.857 1.00 23.59  ? 358 ALA A1 O   1 
ATOM 2548 C CB  . ALA A 1 358 ? 72.894  55.452  -58.329 1.00 16.99  ? 358 ALA A1 CB  1 
ATOM 2549 N N   . ALA A 1 359 ? 76.120  54.751  -59.654 1.00 23.70  ? 359 ALA A1 N   1 
ATOM 2550 C CA  . ALA A 1 359 ? 76.850  54.243  -60.807 1.00 26.58  ? 359 ALA A1 CA  1 
ATOM 2551 C C   . ALA A 1 359 ? 77.994  53.333  -60.380 1.00 29.58  ? 359 ALA A1 C   1 
ATOM 2552 O O   . ALA A 1 359 ? 78.627  53.537  -59.342 1.00 32.61  ? 359 ALA A1 O   1 
ATOM 2553 C CB  . ALA A 1 359 ? 77.415  55.396  -61.640 1.00 26.32  ? 359 ALA A1 CB  1 
ATOM 2554 N N   . GLY A 1 360 ? 78.259  52.320  -61.204 1.00 33.28  ? 360 GLY A1 N   1 
ATOM 2555 C CA  . GLY A 1 360 ? 79.358  51.411  -60.996 1.00 38.58  ? 360 GLY A1 CA  1 
ATOM 2556 C C   . GLY A 1 360 ? 79.729  50.633  -62.246 1.00 41.36  ? 360 GLY A1 C   1 
ATOM 2557 O O   . GLY A 1 360 ? 78.883  50.065  -62.939 1.00 40.94  ? 360 GLY A1 O   1 
ATOM 2558 N N   . ARG A 1 361 ? 81.029  50.621  -62.529 1.00 44.10  ? 361 ARG A1 N   1 
ATOM 2559 C CA  . ARG A 1 361 ? 81.553  49.801  -63.614 1.00 46.77  ? 361 ARG A1 CA  1 
ATOM 2560 C C   . ARG A 1 361 ? 82.921  49.244  -63.228 1.00 48.96  ? 361 ARG A1 C   1 
ATOM 2561 O O   . ARG A 1 361 ? 83.839  49.995  -62.890 1.00 47.43  ? 361 ARG A1 O   1 
ATOM 2562 C CB  . ARG A 1 361 ? 81.638  50.613  -64.905 1.00 47.54  ? 361 ARG A1 CB  1 
ATOM 2563 C CG  . ARG A 1 361 ? 82.125  52.046  -64.753 1.00 49.51  ? 361 ARG A1 CG  1 
ATOM 2564 C CD  . ARG A 1 361 ? 82.194  52.701  -66.116 1.00 51.49  ? 361 ARG A1 CD  1 
ATOM 2565 N NE  . ARG A 1 361 ? 83.265  53.683  -66.228 1.00 53.72  ? 361 ARG A1 NE  1 
ATOM 2566 C CZ  . ARG A 1 361 ? 83.095  54.990  -66.075 1.00 55.01  ? 361 ARG A1 CZ  1 
ATOM 2567 N NH1 . ARG A 1 361 ? 81.893  55.475  -65.796 1.00 55.67  ? 361 ARG A1 NH1 1 
ATOM 2568 N NH2 . ARG A 1 361 ? 84.128  55.812  -66.198 1.00 55.98  ? 361 ARG A1 NH2 1 
ATOM 2569 N N   . GLY A 1 362 ? 83.047  47.919  -63.249 1.00 52.25  ? 362 GLY A1 N   1 
ATOM 2570 C CA  . GLY A 1 362 ? 84.186  47.279  -62.619 1.00 55.76  ? 362 GLY A1 CA  1 
ATOM 2571 C C   . GLY A 1 362 ? 85.556  47.394  -63.262 1.00 58.00  ? 362 GLY A1 C   1 
ATOM 2572 O O   . GLY A 1 362 ? 86.413  48.126  -62.758 1.00 58.96  ? 362 GLY A1 O   1 
ATOM 2573 N N   . GLY A 1 363 ? 85.791  46.688  -64.368 1.00 59.04  ? 363 GLY A1 N   1 
ATOM 2574 C CA  . GLY A 1 363 ? 87.164  46.513  -64.802 1.00 59.72  ? 363 GLY A1 CA  1 
ATOM 2575 C C   . GLY A 1 363 ? 87.568  46.817  -66.231 1.00 60.03  ? 363 GLY A1 C   1 
ATOM 2576 O O   . GLY A 1 363 ? 88.729  47.161  -66.470 1.00 60.83  ? 363 GLY A1 O   1 
ATOM 2577 N N   . ALA A 1 364 ? 86.641  46.705  -67.185 1.00 58.05  ? 364 ALA A1 N   1 
ATOM 2578 C CA  . ALA A 1 364 ? 87.013  46.637  -68.595 1.00 56.09  ? 364 ALA A1 CA  1 
ATOM 2579 C C   . ALA A 1 364 ? 87.474  47.965  -69.175 1.00 55.75  ? 364 ALA A1 C   1 
ATOM 2580 O O   . ALA A 1 364 ? 88.521  48.010  -69.830 1.00 54.50  ? 364 ALA A1 O   1 
ATOM 2581 C CB  . ALA A 1 364 ? 85.838  46.116  -69.429 1.00 54.85  ? 364 ALA A1 CB  1 
ATOM 2582 N N   . GLN A 1 365 ? 86.725  49.038  -68.950 1.00 57.38  ? 365 GLN A1 N   1 
ATOM 2583 C CA  . GLN A 1 365 ? 87.050  50.346  -69.490 1.00 59.86  ? 365 GLN A1 CA  1 
ATOM 2584 C C   . GLN A 1 365 ? 87.656  51.281  -68.457 1.00 60.65  ? 365 GLN A1 C   1 
ATOM 2585 O O   . GLN A 1 365 ? 88.095  52.377  -68.821 1.00 62.20  ? 365 GLN A1 O   1 
ATOM 2586 C CB  . GLN A 1 365 ? 85.792  50.995  -70.083 1.00 60.15  ? 365 GLN A1 CB  1 
ATOM 2587 C CG  . GLN A 1 365 ? 84.678  51.198  -69.067 1.00 64.11  ? 365 GLN A1 CG  1 
ATOM 2588 C CD  . GLN A 1 365 ? 83.695  50.049  -69.041 1.00 66.23  ? 365 GLN A1 CD  1 
ATOM 2589 O OE1 . GLN A 1 365 ? 83.960  48.982  -69.592 1.00 67.37  ? 365 GLN A1 OE1 1 
ATOM 2590 N NE2 . GLN A 1 365 ? 82.561  50.255  -68.390 1.00 65.57  ? 365 GLN A1 NE2 1 
ATOM 2591 N N   . THR A 1 366 ? 87.689  50.881  -67.191 1.00 60.05  ? 366 THR A1 N   1 
ATOM 2592 C CA  . THR A 1 366 ? 88.283  51.686  -66.136 1.00 61.47  ? 366 THR A1 CA  1 
ATOM 2593 C C   . THR A 1 366 ? 89.773  51.393  -66.068 1.00 63.07  ? 366 THR A1 C   1 
ATOM 2594 O O   . THR A 1 366 ? 90.174  50.231  -65.943 1.00 63.41  ? 366 THR A1 O   1 
ATOM 2595 C CB  . THR A 1 366 ? 87.624  51.388  -64.791 1.00 60.90  ? 366 THR A1 CB  1 
ATOM 2596 O OG1 . THR A 1 366 ? 88.193  50.196  -64.233 1.00 60.25  ? 366 THR A1 OG1 1 
ATOM 2597 C CG2 . THR A 1 366 ? 86.129  51.201  -64.959 1.00 59.21  ? 366 THR A1 CG2 1 
ATOM 2598 N N   . ASP A 1 367 ? 90.591  52.436  -66.148 1.00 64.58  ? 367 ASP A1 N   1 
ATOM 2599 C CA  . ASP A 1 367 ? 92.014  52.283  -65.909 1.00 65.25  ? 367 ASP A1 CA  1 
ATOM 2600 C C   . ASP A 1 367 ? 92.275  52.461  -64.416 1.00 63.87  ? 367 ASP A1 C   1 
ATOM 2601 O O   . ASP A 1 367 ? 91.351  52.645  -63.619 1.00 62.47  ? 367 ASP A1 O   1 
ATOM 2602 C CB  . ASP A 1 367 ? 92.826  53.242  -66.792 1.00 68.18  ? 367 ASP A1 CB  1 
ATOM 2603 C CG  . ASP A 1 367 ? 92.244  54.642  -66.848 1.00 70.58  ? 367 ASP A1 CG  1 
ATOM 2604 O OD1 . ASP A 1 367 ? 92.566  55.379  -67.802 1.00 69.98  ? 367 ASP A1 OD1 1 
ATOM 2605 O OD2 . ASP A 1 367 ? 91.481  55.019  -65.943 1.00 71.29  ? 367 ASP A1 OD2 1 
ATOM 2606 N N   . GLU A 1 368 ? 93.545  52.401  -64.020 1.00 62.40  ? 368 GLU A1 N   1 
ATOM 2607 C CA  . GLU A 1 368 ? 93.849  52.346  -62.595 1.00 62.75  ? 368 GLU A1 CA  1 
ATOM 2608 C C   . GLU A 1 368 ? 93.833  53.731  -61.957 1.00 61.40  ? 368 GLU A1 C   1 
ATOM 2609 O O   . GLU A 1 368 ? 93.696  53.851  -60.733 1.00 57.34  ? 368 GLU A1 O   1 
ATOM 2610 C CB  . GLU A 1 368 ? 95.201  51.657  -62.373 1.00 64.62  ? 368 GLU A1 CB  1 
ATOM 2611 C CG  . GLU A 1 368 ? 95.155  50.116  -62.255 1.00 68.34  ? 368 GLU A1 CG  1 
ATOM 2612 C CD  . GLU A 1 368 ? 94.428  49.567  -61.016 1.00 70.30  ? 368 GLU A1 CD  1 
ATOM 2613 O OE1 . GLU A 1 368 ? 94.041  50.333  -60.108 1.00 71.13  ? 368 GLU A1 OE1 1 
ATOM 2614 O OE2 . GLU A 1 368 ? 94.242  48.334  -60.955 1.00 71.09  ? 368 GLU A1 OE2 1 
ATOM 2615 N N   . ASN A 1 369 ? 93.968  54.789  -62.757 1.00 60.73  ? 369 ASN A1 N   1 
ATOM 2616 C CA  . ASN A 1 369 ? 94.059  56.132  -62.189 1.00 61.16  ? 369 ASN A1 CA  1 
ATOM 2617 C C   . ASN A 1 369 ? 92.685  56.791  -62.023 1.00 59.48  ? 369 ASN A1 C   1 
ATOM 2618 O O   . ASN A 1 369 ? 92.375  57.317  -60.950 1.00 59.07  ? 369 ASN A1 O   1 
ATOM 2619 C CB  . ASN A 1 369 ? 95.042  56.988  -63.010 1.00 62.87  ? 369 ASN A1 CB  1 
ATOM 2620 C CG  . ASN A 1 369 ? 94.566  57.276  -64.421 1.00 64.50  ? 369 ASN A1 CG  1 
ATOM 2621 O OD1 . ASN A 1 369 ? 94.733  56.458  -65.325 1.00 65.41  ? 369 ASN A1 OD1 1 
ATOM 2622 N ND2 . ASN A 1 369 ? 93.978  58.452  -64.617 1.00 63.51  ? 369 ASN A1 ND2 1 
ATOM 2623 N N   . GLN A 1 370 ? 91.847  56.764  -63.063 1.00 56.42  ? 370 GLN A1 N   1 
ATOM 2624 C CA  . GLN A 1 370 ? 90.479  57.273  -62.962 1.00 56.35  ? 370 GLN A1 CA  1 
ATOM 2625 C C   . GLN A 1 370 ? 89.534  56.151  -63.371 1.00 55.00  ? 370 GLN A1 C   1 
ATOM 2626 O O   . GLN A 1 370 ? 89.215  55.954  -64.544 1.00 53.61  ? 370 GLN A1 O   1 
ATOM 2627 C CB  . GLN A 1 370 ? 90.284  58.516  -63.822 1.00 57.68  ? 370 GLN A1 CB  1 
ATOM 2628 C CG  . GLN A 1 370 ? 89.243  59.515  -63.286 1.00 59.09  ? 370 GLN A1 CG  1 
ATOM 2629 C CD  . GLN A 1 370 ? 87.853  58.921  -63.103 1.00 60.83  ? 370 GLN A1 CD  1 
ATOM 2630 O OE1 . GLN A 1 370 ? 87.299  58.314  -64.018 1.00 60.99  ? 370 GLN A1 OE1 1 
ATOM 2631 N NE2 . GLN A 1 370 ? 87.292  59.082  -61.912 1.00 61.88  ? 370 GLN A1 NE2 1 
ATOM 2632 N N   . ALA A 1 371 ? 89.065  55.419  -62.364 1.00 54.61  ? 371 ALA A1 N   1 
ATOM 2633 C CA  . ALA A 1 371 ? 88.116  54.336  -62.573 1.00 53.60  ? 371 ALA A1 CA  1 
ATOM 2634 C C   . ALA A 1 371 ? 86.785  54.832  -63.126 1.00 52.22  ? 371 ALA A1 C   1 
ATOM 2635 O O   . ALA A 1 371 ? 86.419  54.490  -64.255 1.00 50.62  ? 371 ALA A1 O   1 
ATOM 2636 C CB  . ALA A 1 371 ? 87.891  53.584  -61.269 1.00 53.30  ? 371 ALA A1 CB  1 
ATOM 2637 N N   . ALA A 1 372 ? 86.074  55.655  -62.360 1.00 49.86  ? 372 ALA A1 N   1 
ATOM 2638 C CA  . ALA A 1 372 ? 84.768  56.161  -62.770 1.00 44.82  ? 372 ALA A1 CA  1 
ATOM 2639 C C   . ALA A 1 372 ? 84.446  57.405  -61.953 1.00 40.52  ? 372 ALA A1 C   1 
ATOM 2640 O O   . ALA A 1 372 ? 85.283  57.927  -61.210 1.00 39.21  ? 372 ALA A1 O   1 
ATOM 2641 C CB  . ALA A 1 372 ? 83.674  55.105  -62.592 1.00 44.82  ? 372 ALA A1 CB  1 
ATOM 2642 N N   . ASP A 1 373 ? 83.215  57.876  -62.111 1.00 35.51  ? 373 ASP A1 N   1 
ATOM 2643 C CA  . ASP A 1 373 ? 82.612  58.865  -61.237 1.00 30.80  ? 373 ASP A1 CA  1 
ATOM 2644 C C   . ASP A 1 373 ? 81.373  58.243  -60.615 1.00 29.23  ? 373 ASP A1 C   1 
ATOM 2645 O O   . ASP A 1 373 ? 80.747  57.351  -61.190 1.00 28.84  ? 373 ASP A1 O   1 
ATOM 2646 C CB  . ASP A 1 373 ? 82.237  60.137  -61.995 1.00 28.87  ? 373 ASP A1 CB  1 
ATOM 2647 C CG  . ASP A 1 373 ? 81.041  59.941  -62.895 1.00 27.57  ? 373 ASP A1 CG  1 
ATOM 2648 O OD1 . ASP A 1 373 ? 79.919  60.300  -62.479 1.00 28.15  ? 373 ASP A1 OD1 1 
ATOM 2649 O OD2 . ASP A 1 373 ? 81.218  59.412  -64.012 1.00 25.89  ? 373 ASP A1 OD2 1 
ATOM 2650 N N   . GLY A 1 374 ? 81.025  58.704  -59.425 1.00 26.13  ? 374 GLY A1 N   1 
ATOM 2651 C CA  . GLY A 1 374 ? 79.909  58.120  -58.724 1.00 22.28  ? 374 GLY A1 CA  1 
ATOM 2652 C C   . GLY A 1 374 ? 80.234  56.871  -57.940 1.00 21.31  ? 374 GLY A1 C   1 
ATOM 2653 O O   . GLY A 1 374 ? 79.321  56.273  -57.358 1.00 22.35  ? 374 GLY A1 O   1 
ATOM 2654 N N   . ASN A 1 375 ? 81.485  56.444  -57.923 1.00 20.15  ? 375 ASN A1 N   1 
ATOM 2655 C CA  . ASN A 1 375 ? 81.868  55.389  -57.012 1.00 19.43  ? 375 ASN A1 CA  1 
ATOM 2656 C C   . ASN A 1 375 ? 82.602  55.982  -55.822 1.00 18.77  ? 375 ASN A1 C   1 
ATOM 2657 O O   . ASN A 1 375 ? 83.576  56.717  -56.002 1.00 21.49  ? 375 ASN A1 O   1 
ATOM 2658 C CB  . ASN A 1 375 ? 82.744  54.333  -57.694 1.00 20.67  ? 375 ASN A1 CB  1 
ATOM 2659 C CG  . ASN A 1 375 ? 83.713  54.929  -58.671 1.00 23.04  ? 375 ASN A1 CG  1 
ATOM 2660 O OD1 . ASN A 1 375 ? 83.804  56.145  -58.808 1.00 24.26  ? 375 ASN A1 OD1 1 
ATOM 2661 N ND2 . ASN A 1 375 ? 84.430  54.076  -59.379 1.00 25.63  ? 375 ASN A1 ND2 1 
ATOM 2662 N N   . PRO A 1 376 ? 82.164  55.668  -54.605 1.00 16.61  ? 376 PRO A1 N   1 
ATOM 2663 C CA  . PRO A 1 376 ? 82.540  56.479  -53.443 1.00 14.73  ? 376 PRO A1 CA  1 
ATOM 2664 C C   . PRO A 1 376 ? 83.981  56.255  -53.021 1.00 13.40  ? 376 PRO A1 C   1 
ATOM 2665 O O   . PRO A 1 376 ? 84.539  55.175  -53.206 1.00 12.32  ? 376 PRO A1 O   1 
ATOM 2666 C CB  . PRO A 1 376 ? 81.566  56.006  -52.364 1.00 14.69  ? 376 PRO A1 CB  1 
ATOM 2667 C CG  . PRO A 1 376 ? 81.271  54.616  -52.745 1.00 12.78  ? 376 PRO A1 CG  1 
ATOM 2668 C CD  . PRO A 1 376 ? 81.222  54.602  -54.234 1.00 14.82  ? 376 PRO A1 CD  1 
ATOM 2669 N N   . ARG A 1 377 ? 84.579  57.297  -52.468 1.00 11.92  ? 377 ARG A1 N   1 
ATOM 2670 C CA  . ARG A 1 377 ? 85.927  57.241  -51.935 1.00 10.67  ? 377 ARG A1 CA  1 
ATOM 2671 C C   . ARG A 1 377 ? 85.879  57.522  -50.443 1.00 9.99   ? 377 ARG A1 C   1 
ATOM 2672 O O   . ARG A 1 377 ? 85.367  58.561  -50.021 1.00 9.76   ? 377 ARG A1 O   1 
ATOM 2673 C CB  . ARG A 1 377 ? 86.825  58.254  -52.633 1.00 10.24  ? 377 ARG A1 CB  1 
ATOM 2674 C CG  . ARG A 1 377 ? 88.190  58.310  -52.041 1.00 9.24   ? 377 ARG A1 CG  1 
ATOM 2675 C CD  . ARG A 1 377 ? 89.139  59.077  -52.894 1.00 8.17   ? 377 ARG A1 CD  1 
ATOM 2676 N NE  . ARG A 1 377 ? 90.506  58.678  -52.612 1.00 8.08   ? 377 ARG A1 NE  1 
ATOM 2677 C CZ  . ARG A 1 377 ? 91.174  57.784  -53.322 1.00 7.10   ? 377 ARG A1 CZ  1 
ATOM 2678 N NH1 . ARG A 1 377 ? 90.600  57.210  -54.362 1.00 5.74   ? 377 ARG A1 NH1 1 
ATOM 2679 N NH2 . ARG A 1 377 ? 92.417  57.472  -52.999 1.00 8.62   ? 377 ARG A1 NH2 1 
ATOM 2680 N N   . TYR A 1 378 ? 86.412  56.602  -49.651 1.00 8.95   ? 378 TYR A1 N   1 
ATOM 2681 C CA  . TYR A 1 378 ? 86.346  56.684  -48.202 1.00 8.43   ? 378 TYR A1 CA  1 
ATOM 2682 C C   . TYR A 1 378 ? 87.694  57.143  -47.682 1.00 9.43   ? 378 TYR A1 C   1 
ATOM 2683 O O   . TYR A 1 378 ? 88.712  56.881  -48.311 1.00 11.19  ? 378 TYR A1 O   1 
ATOM 2684 C CB  . TYR A 1 378 ? 85.969  55.332  -47.599 1.00 7.35   ? 378 TYR A1 CB  1 
ATOM 2685 C CG  . TYR A 1 378 ? 84.542  54.941  -47.875 1.00 6.16   ? 378 TYR A1 CG  1 
ATOM 2686 C CD1 . TYR A 1 378 ? 83.551  55.186  -46.944 1.00 4.52   ? 378 TYR A1 CD1 1 
ATOM 2687 C CD2 . TYR A 1 378 ? 84.179  54.351  -49.072 1.00 6.29   ? 378 TYR A1 CD2 1 
ATOM 2688 C CE1 . TYR A 1 378 ? 82.246  54.848  -47.195 1.00 3.04   ? 378 TYR A1 CE1 1 
ATOM 2689 C CE2 . TYR A 1 378 ? 82.876  54.015  -49.330 1.00 4.60   ? 378 TYR A1 CE2 1 
ATOM 2690 C CZ  . TYR A 1 378 ? 81.918  54.262  -48.387 1.00 3.96   ? 378 TYR A1 CZ  1 
ATOM 2691 O OH  . TYR A 1 378 ? 80.613  53.929  -48.635 1.00 2.11   ? 378 TYR A1 OH  1 
ATOM 2692 N N   . ALA A 1 379 ? 87.695  57.865  -46.567 1.00 9.39   ? 379 ALA A1 N   1 
ATOM 2693 C CA  . ALA A 1 379 ? 88.917  58.253  -45.876 1.00 8.50   ? 379 ALA A1 CA  1 
ATOM 2694 C C   . ALA A 1 379 ? 88.717  57.981  -44.398 1.00 8.40   ? 379 ALA A1 C   1 
ATOM 2695 O O   . ALA A 1 379 ? 87.664  58.309  -43.850 1.00 7.84   ? 379 ALA A1 O   1 
ATOM 2696 C CB  . ALA A 1 379 ? 89.250  59.720  -46.105 1.00 8.97   ? 379 ALA A1 CB  1 
ATOM 2697 N N   . PHE A 1 380 ? 89.718  57.399  -43.748 1.00 7.04   ? 380 PHE A1 N   1 
ATOM 2698 C CA  . PHE A 1 380 ? 89.502  56.868  -42.410 1.00 7.09   ? 380 PHE A1 CA  1 
ATOM 2699 C C   . PHE A 1 380 ? 90.827  56.818  -41.666 1.00 8.26   ? 380 PHE A1 C   1 
ATOM 2700 O O   . PHE A 1 380 ? 91.899  56.919  -42.258 1.00 8.56   ? 380 PHE A1 O   1 
ATOM 2701 C CB  . PHE A 1 380 ? 88.831  55.491  -42.467 1.00 6.21   ? 380 PHE A1 CB  1 
ATOM 2702 C CG  . PHE A 1 380 ? 89.481  54.531  -43.415 1.00 4.36   ? 380 PHE A1 CG  1 
ATOM 2703 C CD1 . PHE A 1 380 ? 90.489  53.697  -42.985 1.00 3.29   ? 380 PHE A1 CD1 1 
ATOM 2704 C CD2 . PHE A 1 380 ? 89.064  54.442  -44.724 1.00 3.71   ? 380 PHE A1 CD2 1 
ATOM 2705 C CE1 . PHE A 1 380 ? 91.081  52.816  -43.846 1.00 4.02   ? 380 PHE A1 CE1 1 
ATOM 2706 C CE2 . PHE A 1 380 ? 89.659  53.579  -45.582 1.00 2.53   ? 380 PHE A1 CE2 1 
ATOM 2707 C CZ  . PHE A 1 380 ? 90.663  52.756  -45.145 1.00 4.01   ? 380 PHE A1 CZ  1 
ATOM 2708 N N   . GLY A 1 381 ? 90.731  56.662  -40.350 1.00 10.46  ? 381 GLY A1 N   1 
ATOM 2709 C CA  . GLY A 1 381 ? 91.892  56.708  -39.487 1.00 12.16  ? 381 GLY A1 CA  1 
ATOM 2710 C C   . GLY A 1 381 ? 92.232  55.371  -38.874 1.00 12.66  ? 381 GLY A1 C   1 
ATOM 2711 O O   . GLY A 1 381 ? 91.676  54.351  -39.281 1.00 13.83  ? 381 GLY A1 O   1 
ATOM 2712 N N   . ARG A 1 382 ? 93.141  55.364  -37.894 1.00 11.78  ? 382 ARG A1 N   1 
ATOM 2713 C CA  . ARG A 1 382 ? 93.653  54.119  -37.330 1.00 11.75  ? 382 ARG A1 CA  1 
ATOM 2714 C C   . ARG A 1 382 ? 92.614  53.379  -36.517 1.00 12.21  ? 382 ARG A1 C   1 
ATOM 2715 O O   . ARG A 1 382 ? 92.743  52.171  -36.307 1.00 13.43  ? 382 ARG A1 O   1 
ATOM 2716 C CB  . ARG A 1 382 ? 94.876  54.406  -36.469 1.00 11.61  ? 382 ARG A1 CB  1 
ATOM 2717 C CG  . ARG A 1 382 ? 95.962  55.088  -37.240 1.00 10.88  ? 382 ARG A1 CG  1 
ATOM 2718 C CD  . ARG A 1 382 ? 97.033  55.632  -36.355 1.00 11.55  ? 382 ARG A1 CD  1 
ATOM 2719 N NE  . ARG A 1 382 ? 97.833  56.582  -37.105 1.00 12.99  ? 382 ARG A1 NE  1 
ATOM 2720 C CZ  . ARG A 1 382 ? 97.544  57.870  -37.215 1.00 13.67  ? 382 ARG A1 CZ  1 
ATOM 2721 N NH1 . ARG A 1 382 ? 96.486  58.373  -36.603 1.00 12.79  ? 382 ARG A1 NH1 1 
ATOM 2722 N NH2 . ARG A 1 382 ? 98.324  58.659  -37.932 1.00 15.17  ? 382 ARG A1 NH2 1 
ATOM 2723 N N   . GLN A 1 383 ? 91.585  54.080  -36.067 1.00 11.38  ? 383 GLN A1 N   1 
ATOM 2724 C CA  . GLN A 1 383 ? 90.504  53.464  -35.328 1.00 9.48   ? 383 GLN A1 CA  1 
ATOM 2725 C C   . GLN A 1 383 ? 89.538  52.716  -36.237 1.00 7.79   ? 383 GLN A1 C   1 
ATOM 2726 O O   . GLN A 1 383 ? 88.762  51.891  -35.753 1.00 5.74   ? 383 GLN A1 O   1 
ATOM 2727 C CB  . GLN A 1 383 ? 89.782  54.558  -34.556 1.00 9.09   ? 383 GLN A1 CB  1 
ATOM 2728 C CG  . GLN A 1 383 ? 89.172  54.138  -33.268 1.00 11.63  ? 383 GLN A1 CG  1 
ATOM 2729 C CD  . GLN A 1 383 ? 88.450  55.281  -32.616 1.00 13.76  ? 383 GLN A1 CD  1 
ATOM 2730 O OE1 . GLN A 1 383 ? 88.391  56.381  -33.158 1.00 16.19  ? 383 GLN A1 OE1 1 
ATOM 2731 N NE2 . GLN A 1 383 ? 87.869  55.026  -31.467 1.00 15.18  ? 383 GLN A1 NE2 1 
ATOM 2732 N N   . HIS A 1 384 ? 89.585  52.973  -37.544 1.00 6.67   ? 384 HIS A1 N   1 
ATOM 2733 C CA  . HIS A 1 384 ? 88.523  52.567  -38.454 1.00 7.56   ? 384 HIS A1 CA  1 
ATOM 2734 C C   . HIS A 1 384 ? 89.042  51.819  -39.672 1.00 9.13   ? 384 HIS A1 C   1 
ATOM 2735 O O   . HIS A 1 384 ? 88.324  51.708  -40.667 1.00 8.36   ? 384 HIS A1 O   1 
ATOM 2736 C CB  . HIS A 1 384 ? 87.723  53.784  -38.907 1.00 7.26   ? 384 HIS A1 CB  1 
ATOM 2737 C CG  . HIS A 1 384 ? 86.927  54.420  -37.818 1.00 8.90   ? 384 HIS A1 CG  1 
ATOM 2738 N ND1 . HIS A 1 384 ? 85.780  53.853  -37.312 1.00 9.16   ? 384 HIS A1 ND1 1 
ATOM 2739 C CD2 . HIS A 1 384 ? 87.102  55.577  -37.143 1.00 8.74   ? 384 HIS A1 CD2 1 
ATOM 2740 C CE1 . HIS A 1 384 ? 85.287  54.630  -36.368 1.00 7.81   ? 384 HIS A1 CE1 1 
ATOM 2741 N NE2 . HIS A 1 384 ? 86.073  55.680  -36.242 1.00 8.59   ? 384 HIS A1 NE2 1 
ATOM 2742 N N   . GLY A 1 385 ? 90.262  51.306  -39.633 1.00 11.18  ? 385 GLY A1 N   1 
ATOM 2743 C CA  . GLY A 1 385 ? 90.731  50.519  -40.751 1.00 12.37  ? 385 GLY A1 CA  1 
ATOM 2744 C C   . GLY A 1 385 ? 92.162  50.767  -41.173 1.00 14.21  ? 385 GLY A1 C   1 
ATOM 2745 O O   . GLY A 1 385 ? 92.775  49.899  -41.800 1.00 15.39  ? 385 GLY A1 O   1 
ATOM 2746 N N   . GLN A 1 386 ? 92.704  51.940  -40.868 1.00 13.32  ? 386 GLN A1 N   1 
ATOM 2747 C CA  . GLN A 1 386 ? 94.111  52.194  -41.130 1.00 11.18  ? 386 GLN A1 CA  1 
ATOM 2748 C C   . GLN A 1 386 ? 94.958  51.366  -40.178 1.00 10.40  ? 386 GLN A1 C   1 
ATOM 2749 O O   . GLN A 1 386 ? 94.499  50.963  -39.109 1.00 8.55   ? 386 GLN A1 O   1 
ATOM 2750 C CB  . GLN A 1 386 ? 94.424  53.680  -40.966 1.00 11.02  ? 386 GLN A1 CB  1 
ATOM 2751 C CG  . GLN A 1 386 ? 95.695  54.161  -41.612 1.00 17.83  ? 386 GLN A1 CG  1 
ATOM 2752 C CD  . GLN A 1 386 ? 95.936  55.622  -41.387 1.00 22.86  ? 386 GLN A1 CD  1 
ATOM 2753 O OE1 . GLN A 1 386 ? 95.097  56.319  -40.833 1.00 24.73  ? 386 GLN A1 OE1 1 
ATOM 2754 N NE2 . GLN A 1 386 ? 97.090  56.099  -41.813 1.00 26.98  ? 386 GLN A1 NE2 1 
ATOM 2755 N N   . LYS A 1 387 ? 96.187  51.076  -40.599 1.00 10.83  ? 387 LYS A1 N   1 
ATOM 2756 C CA  . LYS A 1 387 ? 97.125  50.340  -39.766 1.00 12.06  ? 387 LYS A1 CA  1 
ATOM 2757 C C   . LYS A 1 387 ? 97.453  51.144  -38.520 1.00 13.46  ? 387 LYS A1 C   1 
ATOM 2758 O O   . LYS A 1 387 ? 97.888  52.293  -38.610 1.00 14.51  ? 387 LYS A1 O   1 
ATOM 2759 C CB  . LYS A 1 387 ? 98.389  50.037  -40.558 1.00 13.53  ? 387 LYS A1 CB  1 
ATOM 2760 C CG  . LYS A 1 387 ? 99.373  49.150  -39.840 1.00 14.89  ? 387 LYS A1 CG  1 
ATOM 2761 C CD  . LYS A 1 387 ? 99.143  47.708  -40.195 1.00 18.63  ? 387 LYS A1 CD  1 
ATOM 2762 C CE  . LYS A 1 387 ? 100.224 46.821  -39.630 1.00 22.12  ? 387 LYS A1 CE  1 
ATOM 2763 N NZ  . LYS A 1 387 ? 101.555 47.098  -40.220 1.00 24.15  ? 387 LYS A1 NZ  1 
ATOM 2764 N N   . THR A 1 388 ? 97.243  50.535  -37.355 1.00 13.41  ? 388 THR A1 N   1 
ATOM 2765 C CA  . THR A 1 388 ? 97.309  51.250  -36.091 1.00 13.67  ? 388 THR A1 CA  1 
ATOM 2766 C C   . THR A 1 388 ? 98.726  51.568  -35.634 1.00 16.31  ? 388 THR A1 C   1 
ATOM 2767 O O   . THR A 1 388 ? 98.885  52.169  -34.570 1.00 16.99  ? 388 THR A1 O   1 
ATOM 2768 C CB  . THR A 1 388 ? 96.595  50.450  -35.010 1.00 12.48  ? 388 THR A1 CB  1 
ATOM 2769 O OG1 . THR A 1 388 ? 97.374  49.298  -34.681 1.00 11.94  ? 388 THR A1 OG1 1 
ATOM 2770 C CG2 . THR A 1 388 ? 95.243  50.011  -35.499 1.00 10.83  ? 388 THR A1 CG2 1 
ATOM 2771 N N   . THR A 1 389 ? 99.750  51.180  -36.381 1.00 17.48  ? 389 THR A1 N   1 
ATOM 2772 C CA  . THR A 1 389 ? 101.123 51.583  -36.101 1.00 18.02  ? 389 THR A1 CA  1 
ATOM 2773 C C   . THR A 1 389 ? 101.700 52.444  -37.218 1.00 21.88  ? 389 THR A1 C   1 
ATOM 2774 O O   . THR A 1 389 ? 102.840 52.257  -37.643 1.00 26.47  ? 389 THR A1 O   1 
ATOM 2775 C CB  . THR A 1 389 ? 102.013 50.369  -35.852 1.00 15.94  ? 389 THR A1 CB  1 
ATOM 2776 O OG1 . THR A 1 389 ? 102.163 49.619  -37.061 1.00 14.28  ? 389 THR A1 OG1 1 
ATOM 2777 C CG2 . THR A 1 389 ? 101.445 49.497  -34.756 1.00 14.87  ? 389 THR A1 CG2 1 
ATOM 2778 N N   . THR A 1 390 ? 100.909 53.389  -37.717 1.00 23.36  ? 390 THR A1 N   1 
ATOM 2779 C CA  . THR A 1 390 ? 101.377 54.393  -38.665 1.00 23.83  ? 390 THR A1 CA  1 
ATOM 2780 C C   . THR A 1 390 ? 101.257 55.765  -38.022 1.00 23.86  ? 390 THR A1 C   1 
ATOM 2781 O O   . THR A 1 390 ? 100.151 56.209  -37.708 1.00 23.76  ? 390 THR A1 O   1 
ATOM 2782 C CB  . THR A 1 390 ? 100.574 54.360  -39.963 1.00 24.49  ? 390 THR A1 CB  1 
ATOM 2783 O OG1 . THR A 1 390 ? 99.230  54.778  -39.701 1.00 25.90  ? 390 THR A1 OG1 1 
ATOM 2784 C CG2 . THR A 1 390 ? 100.573 52.984  -40.564 1.00 25.63  ? 390 THR A1 CG2 1 
ATOM 2785 N N   . THR A 1 391 ? 102.387 56.439  -37.839 1.00 25.71  ? 391 THR A1 N   1 
ATOM 2786 C CA  . THR A 1 391 ? 102.399 57.786  -37.275 1.00 27.19  ? 391 THR A1 CA  1 
ATOM 2787 C C   . THR A 1 391 ? 102.309 58.771  -38.431 1.00 27.62  ? 391 THR A1 C   1 
ATOM 2788 O O   . THR A 1 391 ? 103.194 58.825  -39.286 1.00 29.79  ? 391 THR A1 O   1 
ATOM 2789 C CB  . THR A 1 391 ? 103.654 58.017  -36.441 1.00 28.34  ? 391 THR A1 CB  1 
ATOM 2790 O OG1 . THR A 1 391 ? 104.794 57.494  -37.135 1.00 31.67  ? 391 THR A1 OG1 1 
ATOM 2791 C CG2 . THR A 1 391 ? 103.528 57.325  -35.093 1.00 29.83  ? 391 THR A1 CG2 1 
ATOM 2792 N N   . GLY A 1 392 ? 101.235 59.546  -38.467 1.00 28.40  ? 392 GLY A1 N   1 
ATOM 2793 C CA  . GLY A 1 392 ? 101.030 60.465  -39.565 1.00 30.08  ? 392 GLY A1 CA  1 
ATOM 2794 C C   . GLY A 1 392 ? 99.744  61.241  -39.388 1.00 30.77  ? 392 GLY A1 C   1 
ATOM 2795 O O   . GLY A 1 392 ? 98.869  60.874  -38.597 1.00 31.89  ? 392 GLY A1 O   1 
ATOM 2796 N N   . GLU A 1 393 ? 99.658  62.340  -40.131 1.00 31.47  ? 393 GLU A1 N   1 
ATOM 2797 C CA  . GLU A 1 393 ? 98.448  63.146  -40.184 1.00 31.49  ? 393 GLU A1 CA  1 
ATOM 2798 C C   . GLU A 1 393 ? 97.474  62.658  -41.244 1.00 27.69  ? 393 GLU A1 C   1 
ATOM 2799 O O   . GLU A 1 393 ? 96.259  62.779  -41.056 1.00 29.19  ? 393 GLU A1 O   1 
ATOM 2800 C CB  . GLU A 1 393 ? 98.819  64.614  -40.451 1.00 36.08  ? 393 GLU A1 CB  1 
ATOM 2801 C CG  . GLU A 1 393 ? 97.686  65.630  -40.302 1.00 42.63  ? 393 GLU A1 CG  1 
ATOM 2802 C CD  . GLU A 1 393 ? 97.215  66.212  -41.630 1.00 46.33  ? 393 GLU A1 CD  1 
ATOM 2803 O OE1 . GLU A 1 393 ? 96.211  66.955  -41.629 1.00 48.82  ? 393 GLU A1 OE1 1 
ATOM 2804 O OE2 . GLU A 1 393 ? 97.843  65.932  -42.672 1.00 48.11  ? 393 GLU A1 OE2 1 
ATOM 2805 N N   . THR A 1 394 ? 97.981  62.079  -42.329 1.00 22.17  ? 394 THR A1 N   1 
ATOM 2806 C CA  . THR A 1 394 ? 97.142  61.755  -43.469 1.00 18.38  ? 394 THR A1 CA  1 
ATOM 2807 C C   . THR A 1 394 ? 96.332  60.488  -43.203 1.00 15.21  ? 394 THR A1 C   1 
ATOM 2808 O O   . THR A 1 394 ? 96.791  59.593  -42.489 1.00 15.95  ? 394 THR A1 O   1 
ATOM 2809 C CB  . THR A 1 394 ? 98.003  61.596  -44.724 1.00 18.35  ? 394 THR A1 CB  1 
ATOM 2810 O OG1 . THR A 1 394 ? 97.191  61.169  -45.823 1.00 20.01  ? 394 THR A1 OG1 1 
ATOM 2811 C CG2 . THR A 1 394 ? 99.131  60.606  -44.501 1.00 18.13  ? 394 THR A1 CG2 1 
ATOM 2812 N N   . PRO A 1 395 ? 95.111  60.402  -43.718 1.00 11.61  ? 395 PRO A1 N   1 
ATOM 2813 C CA  . PRO A 1 395 ? 94.306  59.196  -43.544 1.00 10.38  ? 395 PRO A1 CA  1 
ATOM 2814 C C   . PRO A 1 395 ? 94.641  58.140  -44.589 1.00 11.06  ? 395 PRO A1 C   1 
ATOM 2815 O O   . PRO A 1 395 ? 95.540  58.301  -45.414 1.00 12.90  ? 395 PRO A1 O   1 
ATOM 2816 C CB  . PRO A 1 395 ? 92.880  59.715  -43.730 1.00 9.27   ? 395 PRO A1 CB  1 
ATOM 2817 C CG  . PRO A 1 395 ? 93.024  60.824  -44.635 1.00 10.87  ? 395 PRO A1 CG  1 
ATOM 2818 C CD  . PRO A 1 395 ? 94.298  61.501  -44.257 1.00 11.58  ? 395 PRO A1 CD  1 
ATOM 2819 N N   . GLU A 1 396 ? 93.898  57.045  -44.528 1.00 11.75  ? 396 GLU A1 N   1 
ATOM 2820 C CA  . GLU A 1 396 ? 93.975  55.990  -45.520 1.00 12.93  ? 396 GLU A1 CA  1 
ATOM 2821 C C   . GLU A 1 396 ? 92.715  56.022  -46.359 1.00 14.05  ? 396 GLU A1 C   1 
ATOM 2822 O O   . GLU A 1 396 ? 91.616  56.209  -45.841 1.00 15.68  ? 396 GLU A1 O   1 
ATOM 2823 C CB  . GLU A 1 396 ? 94.133  54.620  -44.863 1.00 15.76  ? 396 GLU A1 CB  1 
ATOM 2824 C CG  . GLU A 1 396 ? 94.180  53.455  -45.819 1.00 22.62  ? 396 GLU A1 CG  1 
ATOM 2825 C CD  . GLU A 1 396 ? 95.203  52.427  -45.423 1.00 27.45  ? 396 GLU A1 CD  1 
ATOM 2826 O OE1 . GLU A 1 396 ? 94.911  51.218  -45.538 1.00 29.54  ? 396 GLU A1 OE1 1 
ATOM 2827 O OE2 . GLU A 1 396 ? 96.307  52.827  -44.997 1.00 29.87  ? 396 GLU A1 OE2 1 
ATOM 2828 N N   . ARG A 1 397 ? 92.874  55.859  -47.664 1.00 12.47  ? 397 ARG A1 N   1 
ATOM 2829 C CA  . ARG A 1 397 ? 91.742  55.920  -48.564 1.00 10.44  ? 397 ARG A1 CA  1 
ATOM 2830 C C   . ARG A 1 397 ? 91.665  54.687  -49.443 1.00 9.21   ? 397 ARG A1 C   1 
ATOM 2831 O O   . ARG A 1 397 ? 92.679  54.042  -49.715 1.00 12.22  ? 397 ARG A1 O   1 
ATOM 2832 C CB  . ARG A 1 397 ? 91.809  57.160  -49.440 1.00 9.57   ? 397 ARG A1 CB  1 
ATOM 2833 C CG  . ARG A 1 397 ? 91.666  58.444  -48.672 1.00 11.33  ? 397 ARG A1 CG  1 
ATOM 2834 C CD  . ARG A 1 397 ? 92.088  59.611  -49.509 1.00 14.30  ? 397 ARG A1 CD  1 
ATOM 2835 N NE  . ARG A 1 397 ? 92.658  60.690  -48.715 1.00 17.60  ? 397 ARG A1 NE  1 
ATOM 2836 C CZ  . ARG A 1 397 ? 93.926  60.740  -48.334 1.00 19.78  ? 397 ARG A1 CZ  1 
ATOM 2837 N NH1 . ARG A 1 397 ? 94.758  59.764  -48.664 1.00 22.12  ? 397 ARG A1 NH1 1 
ATOM 2838 N NH2 . ARG A 1 397 ? 94.366  61.766  -47.627 1.00 20.32  ? 397 ARG A1 NH2 1 
ATOM 2839 N N   . PHE A 1 398 ? 90.450  54.357  -49.865 1.00 6.60   ? 398 PHE A1 N   1 
ATOM 2840 C CA  . PHE A 1 398 ? 90.231  53.502  -51.016 1.00 5.84   ? 398 PHE A1 CA  1 
ATOM 2841 C C   . PHE A 1 398 ? 89.099  54.082  -51.842 1.00 6.79   ? 398 PHE A1 C   1 
ATOM 2842 O O   . PHE A 1 398 ? 88.392  54.987  -51.399 1.00 7.30   ? 398 PHE A1 O   1 
ATOM 2843 C CB  . PHE A 1 398 ? 89.923  52.038  -50.632 1.00 4.56   ? 398 PHE A1 CB  1 
ATOM 2844 C CG  . PHE A 1 398 ? 88.691  51.852  -49.789 1.00 4.49   ? 398 PHE A1 CG  1 
ATOM 2845 C CD1 . PHE A 1 398 ? 87.453  51.616  -50.362 1.00 5.21   ? 398 PHE A1 CD1 1 
ATOM 2846 C CD2 . PHE A 1 398 ? 88.784  51.854  -48.422 1.00 3.92   ? 398 PHE A1 CD2 1 
ATOM 2847 C CE1 . PHE A 1 398 ? 86.343  51.437  -49.582 1.00 6.09   ? 398 PHE A1 CE1 1 
ATOM 2848 C CE2 . PHE A 1 398 ? 87.674  51.664  -47.644 1.00 3.33   ? 398 PHE A1 CE2 1 
ATOM 2849 C CZ  . PHE A 1 398 ? 86.459  51.457  -48.223 1.00 4.64   ? 398 PHE A1 CZ  1 
ATOM 2850 N N   . THR A 1 399 ? 88.941  53.560  -53.050 1.00 7.02   ? 399 THR A1 N   1 
ATOM 2851 C CA  . THR A 1 399 ? 87.780  53.836  -53.880 1.00 8.10   ? 399 THR A1 CA  1 
ATOM 2852 C C   . THR A 1 399 ? 87.047  52.527  -54.118 1.00 11.23  ? 399 THR A1 C   1 
ATOM 2853 O O   . THR A 1 399 ? 87.612  51.588  -54.684 1.00 13.72  ? 399 THR A1 O   1 
ATOM 2854 C CB  . THR A 1 399 ? 88.174  54.470  -55.207 1.00 4.92   ? 399 THR A1 CB  1 
ATOM 2855 O OG1 . THR A 1 399 ? 88.828  55.715  -54.960 1.00 5.18   ? 399 THR A1 OG1 1 
ATOM 2856 C CG2 . THR A 1 399 ? 86.944  54.738  -56.024 1.00 2.69   ? 399 THR A1 CG2 1 
ATOM 2857 N N   . TYR A 1 400 ? 85.800  52.461  -53.678 1.00 12.99  ? 400 TYR A1 N   1 
ATOM 2858 C CA  . TYR A 1 400 ? 85.028  51.234  -53.784 1.00 13.00  ? 400 TYR A1 CA  1 
ATOM 2859 C C   . TYR A 1 400 ? 84.511  51.099  -55.208 1.00 13.26  ? 400 TYR A1 C   1 
ATOM 2860 O O   . TYR A 1 400 ? 83.638  51.858  -55.634 1.00 13.43  ? 400 TYR A1 O   1 
ATOM 2861 C CB  . TYR A 1 400 ? 83.887  51.241  -52.776 1.00 12.43  ? 400 TYR A1 CB  1 
ATOM 2862 C CG  . TYR A 1 400 ? 83.111  49.958  -52.759 1.00 11.31  ? 400 TYR A1 CG  1 
ATOM 2863 C CD1 . TYR A 1 400 ? 83.581  48.849  -52.080 1.00 11.86  ? 400 TYR A1 CD1 1 
ATOM 2864 C CD2 . TYR A 1 400 ? 81.914  49.851  -53.442 1.00 10.62  ? 400 TYR A1 CD2 1 
ATOM 2865 C CE1 . TYR A 1 400 ? 82.873  47.675  -52.075 1.00 10.46  ? 400 TYR A1 CE1 1 
ATOM 2866 C CE2 . TYR A 1 400 ? 81.215  48.686  -53.453 1.00 9.57   ? 400 TYR A1 CE2 1 
ATOM 2867 C CZ  . TYR A 1 400 ? 81.687  47.603  -52.764 1.00 9.73   ? 400 TYR A1 CZ  1 
ATOM 2868 O OH  . TYR A 1 400 ? 80.964  46.437  -52.779 1.00 10.57  ? 400 TYR A1 OH  1 
ATOM 2869 N N   . ILE A 1 401 ? 85.046  50.135  -55.949 1.00 12.95  ? 401 ILE A1 N   1 
ATOM 2870 C CA  . ILE A 1 401 ? 84.591  49.832  -57.300 1.00 13.50  ? 401 ILE A1 CA  1 
ATOM 2871 C C   . ILE A 1 401 ? 83.604  48.683  -57.190 1.00 14.05  ? 401 ILE A1 C   1 
ATOM 2872 O O   . ILE A 1 401 ? 83.991  47.554  -56.879 1.00 14.07  ? 401 ILE A1 O   1 
ATOM 2873 C CB  . ILE A 1 401 ? 85.751  49.462  -58.228 1.00 13.51  ? 401 ILE A1 CB  1 
ATOM 2874 C CG1 . ILE A 1 401 ? 86.953  50.370  -57.989 1.00 14.21  ? 401 ILE A1 CG1 1 
ATOM 2875 C CG2 . ILE A 1 401 ? 85.310  49.561  -59.668 1.00 13.89  ? 401 ILE A1 CG2 1 
ATOM 2876 C CD1 . ILE A 1 401 ? 86.711  51.792  -58.315 1.00 16.83  ? 401 ILE A1 CD1 1 
ATOM 2877 N N   . ALA A 1 402 ? 82.331  48.953  -57.451 1.00 15.22  ? 402 ALA A1 N   1 
ATOM 2878 C CA  . ALA A 1 402 ? 81.312  47.930  -57.301 1.00 15.95  ? 402 ALA A1 CA  1 
ATOM 2879 C C   . ALA A 1 402 ? 81.409  46.901  -58.422 1.00 17.20  ? 402 ALA A1 C   1 
ATOM 2880 O O   . ALA A 1 402 ? 81.872  47.182  -59.528 1.00 21.92  ? 402 ALA A1 O   1 
ATOM 2881 C CB  . ALA A 1 402 ? 79.927  48.564  -57.283 1.00 16.60  ? 402 ALA A1 CB  1 
ATOM 2882 N N   . HIS A 1 403 ? 80.961  45.686  -58.121 1.00 17.14  ? 403 HIS A1 N   1 
ATOM 2883 C CA  . HIS A 1 403 ? 80.952  44.610  -59.099 1.00 15.45  ? 403 HIS A1 CA  1 
ATOM 2884 C C   . HIS A 1 403 ? 79.793  44.687  -60.072 1.00 15.39  ? 403 HIS A1 C   1 
ATOM 2885 O O   . HIS A 1 403 ? 79.869  44.073  -61.140 1.00 15.81  ? 403 HIS A1 O   1 
ATOM 2886 C CB  . HIS A 1 403 ? 80.918  43.254  -58.396 1.00 15.79  ? 403 HIS A1 CB  1 
ATOM 2887 C CG  . HIS A 1 403 ? 82.260  42.758  -57.976 1.00 17.80  ? 403 HIS A1 CG  1 
ATOM 2888 N ND1 . HIS A 1 403 ? 82.426  41.762  -57.041 1.00 19.88  ? 403 HIS A1 ND1 1 
ATOM 2889 C CD2 . HIS A 1 403 ? 83.500  43.078  -58.410 1.00 18.86  ? 403 HIS A1 CD2 1 
ATOM 2890 C CE1 . HIS A 1 403 ? 83.713  41.519  -56.887 1.00 18.76  ? 403 HIS A1 CE1 1 
ATOM 2891 N NE2 . HIS A 1 403 ? 84.387  42.301  -57.709 1.00 19.78  ? 403 HIS A1 NE2 1 
ATOM 2892 N N   . GLN A 1 404 ? 78.730  45.410  -59.730 1.00 14.55  ? 404 GLN A1 N   1 
ATOM 2893 C CA  . GLN A 1 404 ? 77.575  45.511  -60.610 1.00 14.47  ? 404 GLN A1 CA  1 
ATOM 2894 C C   . GLN A 1 404 ? 77.933  46.310  -61.853 1.00 14.80  ? 404 GLN A1 C   1 
ATOM 2895 O O   . GLN A 1 404 ? 78.521  47.392  -61.768 1.00 15.88  ? 404 GLN A1 O   1 
ATOM 2896 C CB  . GLN A 1 404 ? 76.394  46.141  -59.879 1.00 15.14  ? 404 GLN A1 CB  1 
ATOM 2897 C CG  . GLN A 1 404 ? 76.705  47.416  -59.137 1.00 15.95  ? 404 GLN A1 CG  1 
ATOM 2898 C CD  . GLN A 1 404 ? 75.497  47.974  -58.446 1.00 16.06  ? 404 GLN A1 CD  1 
ATOM 2899 O OE1 . GLN A 1 404 ? 74.396  47.461  -58.608 1.00 14.54  ? 404 GLN A1 OE1 1 
ATOM 2900 N NE2 . GLN A 1 404 ? 75.690  49.026  -57.665 1.00 18.43  ? 404 GLN A1 NE2 1 
ATOM 2901 N N   . ASP A 1 405 ? 77.624  45.745  -63.015 1.00 15.19  ? 405 ASP A1 N   1 
ATOM 2902 C CA  . ASP A 1 405 ? 77.937  46.386  -64.287 1.00 14.89  ? 405 ASP A1 CA  1 
ATOM 2903 C C   . ASP A 1 405 ? 76.682  47.112  -64.753 1.00 15.65  ? 405 ASP A1 C   1 
ATOM 2904 O O   . ASP A 1 405 ? 76.018  46.735  -65.718 1.00 17.90  ? 405 ASP A1 O   1 
ATOM 2905 C CB  . ASP A 1 405 ? 78.441  45.355  -65.289 1.00 14.95  ? 405 ASP A1 CB  1 
ATOM 2906 C CG  . ASP A 1 405 ? 79.768  44.725  -64.867 1.00 19.03  ? 405 ASP A1 CG  1 
ATOM 2907 O OD1 . ASP A 1 405 ? 79.802  43.527  -64.526 1.00 16.10  ? 405 ASP A1 OD1 1 
ATOM 2908 O OD2 . ASP A 1 405 ? 80.789  45.440  -64.869 1.00 22.41  ? 405 ASP A1 OD2 1 
ATOM 2909 N N   . THR A 1 406 ? 76.356  48.189  -64.036 1.00 13.90  ? 406 THR A1 N   1 
ATOM 2910 C CA  . THR A 1 406 ? 75.152  48.966  -64.297 1.00 11.11  ? 406 THR A1 CA  1 
ATOM 2911 C C   . THR A 1 406 ? 75.457  50.431  -64.593 1.00 11.76  ? 406 THR A1 C   1 
ATOM 2912 O O   . THR A 1 406 ? 74.530  51.203  -64.854 1.00 11.21  ? 406 THR A1 O   1 
ATOM 2913 C CB  . THR A 1 406 ? 74.181  48.860  -63.112 1.00 9.61   ? 406 THR A1 CB  1 
ATOM 2914 O OG1 . THR A 1 406 ? 72.882  49.312  -63.504 1.00 9.04   ? 406 THR A1 OG1 1 
ATOM 2915 C CG2 . THR A 1 406 ? 74.664  49.693  -61.936 1.00 8.53   ? 406 THR A1 CG2 1 
ATOM 2916 N N   . GLY A 1 407 ? 76.721  50.826  -64.593 1.00 12.09  ? 407 GLY A1 N   1 
ATOM 2917 C CA  . GLY A 1 407 ? 77.114  52.198  -64.844 1.00 12.69  ? 407 GLY A1 CA  1 
ATOM 2918 C C   . GLY A 1 407 ? 77.110  52.560  -66.312 1.00 12.23  ? 407 GLY A1 C   1 
ATOM 2919 O O   . GLY A 1 407 ? 76.415  51.950  -67.128 1.00 11.13  ? 407 GLY A1 O   1 
ATOM 2920 N N   . ARG A 1 408 ? 77.891  53.582  -66.653 1.00 10.84  ? 408 ARG A1 N   1 
ATOM 2921 C CA  . ARG A 1 408 ? 77.961  54.089  -68.013 1.00 9.77   ? 408 ARG A1 CA  1 
ATOM 2922 C C   . ARG A 1 408 ? 79.399  54.423  -68.360 1.00 11.63  ? 408 ARG A1 C   1 
ATOM 2923 O O   . ARG A 1 408 ? 80.164  54.890  -67.515 1.00 14.19  ? 408 ARG A1 O   1 
ATOM 2924 C CB  . ARG A 1 408 ? 77.112  55.343  -68.202 1.00 6.26   ? 408 ARG A1 CB  1 
ATOM 2925 C CG  . ARG A 1 408 ? 75.639  55.088  -68.336 1.00 2.95   ? 408 ARG A1 CG  1 
ATOM 2926 C CD  . ARG A 1 408 ? 75.311  54.420  -69.636 1.00 2.98   ? 408 ARG A1 CD  1 
ATOM 2927 N NE  . ARG A 1 408 ? 73.875  54.251  -69.775 1.00 2.72   ? 408 ARG A1 NE  1 
ATOM 2928 C CZ  . ARG A 1 408 ? 73.224  53.159  -69.408 1.00 3.05   ? 408 ARG A1 CZ  1 
ATOM 2929 N NH1 . ARG A 1 408 ? 73.890  52.145  -68.884 1.00 3.52   ? 408 ARG A1 NH1 1 
ATOM 2930 N NH2 . ARG A 1 408 ? 71.914  53.080  -69.561 1.00 2.52   ? 408 ARG A1 NH2 1 
ATOM 2931 N N   . TYR A 1 409 ? 79.757  54.190  -69.616 1.00 12.58  ? 409 TYR A1 N   1 
ATOM 2932 C CA  . TYR A 1 409 ? 81.053  54.592  -70.130 1.00 12.56  ? 409 TYR A1 CA  1 
ATOM 2933 C C   . TYR A 1 409 ? 80.851  55.791  -71.037 1.00 10.61  ? 409 TYR A1 C   1 
ATOM 2934 O O   . TYR A 1 409 ? 80.429  55.613  -72.186 1.00 10.67  ? 409 TYR A1 O   1 
ATOM 2935 C CB  . TYR A 1 409 ? 81.704  53.448  -70.896 1.00 15.52  ? 409 TYR A1 CB  1 
ATOM 2936 C CG  . TYR A 1 409 ? 83.117  53.726  -71.318 1.00 19.94  ? 409 TYR A1 CG  1 
ATOM 2937 C CD1 . TYR A 1 409 ? 83.981  54.420  -70.489 1.00 20.93  ? 409 TYR A1 CD1 1 
ATOM 2938 C CD2 . TYR A 1 409 ? 83.587  53.297  -72.548 1.00 19.96  ? 409 TYR A1 CD2 1 
ATOM 2939 C CE1 . TYR A 1 409 ? 85.277  54.675  -70.870 1.00 23.66  ? 409 TYR A1 CE1 1 
ATOM 2940 C CE2 . TYR A 1 409 ? 84.881  53.549  -72.940 1.00 22.35  ? 409 TYR A1 CE2 1 
ATOM 2941 C CZ  . TYR A 1 409 ? 85.721  54.240  -72.096 1.00 25.49  ? 409 TYR A1 CZ  1 
ATOM 2942 O OH  . TYR A 1 409 ? 87.016  54.495  -72.476 1.00 29.28  ? 409 TYR A1 OH  1 
ATOM 2943 N N   . PRO A 1 410 ? 81.127  57.016  -70.581 1.00 9.03   ? 410 PRO A1 N   1 
ATOM 2944 C CA  . PRO A 1 410 ? 80.746  58.198  -71.369 1.00 11.45  ? 410 PRO A1 CA  1 
ATOM 2945 C C   . PRO A 1 410 ? 81.600  58.432  -72.599 1.00 15.47  ? 410 PRO A1 C   1 
ATOM 2946 O O   . PRO A 1 410 ? 81.184  59.187  -73.483 1.00 17.63  ? 410 PRO A1 O   1 
ATOM 2947 C CB  . PRO A 1 410 ? 80.898  59.350  -70.369 1.00 9.08   ? 410 PRO A1 CB  1 
ATOM 2948 C CG  . PRO A 1 410 ? 80.930  58.703  -69.037 1.00 8.52   ? 410 PRO A1 CG  1 
ATOM 2949 C CD  . PRO A 1 410 ? 81.597  57.393  -69.244 1.00 8.02   ? 410 PRO A1 CD  1 
ATOM 2950 N N   . GLU A 1 411 ? 82.769  57.810  -72.696 1.00 17.92  ? 411 GLU A1 N   1 
ATOM 2951 C CA  . GLU A 1 411 ? 83.583  57.914  -73.898 1.00 19.81  ? 411 GLU A1 CA  1 
ATOM 2952 C C   . GLU A 1 411 ? 83.053  57.078  -75.054 1.00 17.90  ? 411 GLU A1 C   1 
ATOM 2953 O O   . GLU A 1 411 ? 83.582  57.182  -76.162 1.00 19.50  ? 411 GLU A1 O   1 
ATOM 2954 C CB  . GLU A 1 411 ? 85.020  57.496  -73.591 1.00 26.06  ? 411 GLU A1 CB  1 
ATOM 2955 C CG  . GLU A 1 411 ? 85.782  58.468  -72.715 1.00 34.68  ? 411 GLU A1 CG  1 
ATOM 2956 C CD  . GLU A 1 411 ? 85.672  58.149  -71.237 1.00 39.65  ? 411 GLU A1 CD  1 
ATOM 2957 O OE1 . GLU A 1 411 ? 86.723  58.034  -70.577 1.00 42.55  ? 411 GLU A1 OE1 1 
ATOM 2958 O OE2 . GLU A 1 411 ? 84.541  58.029  -70.728 1.00 43.10  ? 411 GLU A1 OE2 1 
ATOM 2959 N N   . GLY A 1 412 ? 82.038  56.253  -74.827 1.00 15.06  ? 412 GLY A1 N   1 
ATOM 2960 C CA  . GLY A 1 412 ? 81.489  55.416  -75.867 1.00 12.16  ? 412 GLY A1 CA  1 
ATOM 2961 C C   . GLY A 1 412 ? 80.072  55.788  -76.243 1.00 11.16  ? 412 GLY A1 C   1 
ATOM 2962 O O   . GLY A 1 412 ? 79.388  55.019  -76.921 1.00 11.93  ? 412 GLY A1 O   1 
ATOM 2963 N N   . ASP A 1 413 ? 79.615  56.953  -75.800 1.00 10.09  ? 413 ASP A1 N   1 
ATOM 2964 C CA  . ASP A 1 413 ? 78.302  57.456  -76.169 1.00 10.81  ? 413 ASP A1 CA  1 
ATOM 2965 C C   . ASP A 1 413 ? 78.414  58.372  -77.377 1.00 12.11  ? 413 ASP A1 C   1 
ATOM 2966 O O   . ASP A 1 413 ? 79.436  59.009  -77.591 1.00 15.30  ? 413 ASP A1 O   1 
ATOM 2967 C CB  . ASP A 1 413 ? 77.666  58.228  -75.014 1.00 9.88   ? 413 ASP A1 CB  1 
ATOM 2968 C CG  . ASP A 1 413 ? 77.476  57.383  -73.772 1.00 12.03  ? 413 ASP A1 CG  1 
ATOM 2969 O OD1 . ASP A 1 413 ? 77.196  56.177  -73.904 1.00 14.94  ? 413 ASP A1 OD1 1 
ATOM 2970 O OD2 . ASP A 1 413 ? 77.588  57.934  -72.659 1.00 10.99  ? 413 ASP A1 OD2 1 
ATOM 2971 N N   . TRP A 1 414 ? 77.355  58.426  -78.176 1.00 11.42  ? 414 TRP A1 N   1 
ATOM 2972 C CA  . TRP A 1 414 ? 77.290  59.392  -79.262 1.00 11.39  ? 414 TRP A1 CA  1 
ATOM 2973 C C   . TRP A 1 414 ? 75.832  59.699  -79.544 1.00 12.95  ? 414 TRP A1 C   1 
ATOM 2974 O O   . TRP A 1 414 ? 74.979  58.814  -79.493 1.00 15.24  ? 414 TRP A1 O   1 
ATOM 2975 C CB  . TRP A 1 414 ? 77.999  58.889  -80.528 1.00 9.63   ? 414 TRP A1 CB  1 
ATOM 2976 C CG  . TRP A 1 414 ? 77.362  57.724  -81.210 1.00 8.43   ? 414 TRP A1 CG  1 
ATOM 2977 C CD1 . TRP A 1 414 ? 76.502  57.761  -82.255 1.00 7.29   ? 414 TRP A1 CD1 1 
ATOM 2978 C CD2 . TRP A 1 414 ? 77.564  56.344  -80.906 1.00 7.73   ? 414 TRP A1 CD2 1 
ATOM 2979 N NE1 . TRP A 1 414 ? 76.138  56.493  -82.614 1.00 6.68   ? 414 TRP A1 NE1 1 
ATOM 2980 C CE2 . TRP A 1 414 ? 76.782  55.603  -81.798 1.00 6.72   ? 414 TRP A1 CE2 1 
ATOM 2981 C CE3 . TRP A 1 414 ? 78.328  55.666  -79.958 1.00 8.08   ? 414 TRP A1 CE3 1 
ATOM 2982 C CZ2 . TRP A 1 414 ? 76.737  54.221  -81.771 1.00 6.13   ? 414 TRP A1 CZ2 1 
ATOM 2983 C CZ3 . TRP A 1 414 ? 78.286  54.299  -79.934 1.00 7.83   ? 414 TRP A1 CZ3 1 
ATOM 2984 C CH2 . TRP A 1 414 ? 77.495  53.588  -80.832 1.00 6.74   ? 414 TRP A1 CH2 1 
ATOM 2985 N N   . ILE A 1 415 ? 75.554  60.969  -79.816 1.00 12.11  ? 415 ILE A1 N   1 
ATOM 2986 C CA  . ILE A 1 415 ? 74.246  61.425  -80.266 1.00 10.63  ? 415 ILE A1 CA  1 
ATOM 2987 C C   . ILE A 1 415 ? 74.363  61.667  -81.754 1.00 11.54  ? 415 ILE A1 C   1 
ATOM 2988 O O   . ILE A 1 415 ? 75.235  62.423  -82.189 1.00 14.30  ? 415 ILE A1 O   1 
ATOM 2989 C CB  . ILE A 1 415 ? 73.810  62.712  -79.544 1.00 9.72   ? 415 ILE A1 CB  1 
ATOM 2990 C CG1 . ILE A 1 415 ? 73.305  62.402  -78.146 1.00 9.51   ? 415 ILE A1 CG1 1 
ATOM 2991 C CG2 . ILE A 1 415 ? 72.718  63.424  -80.300 1.00 8.25   ? 415 ILE A1 CG2 1 
ATOM 2992 C CD1 . ILE A 1 415 ? 72.115  61.510  -78.120 1.00 10.28  ? 415 ILE A1 CD1 1 
ATOM 2993 N N   . GLN A 1 416 ? 73.518  61.020  -82.540 1.00 10.88  ? 416 GLN A1 N   1 
ATOM 2994 C CA  . GLN A 1 416 ? 73.574  61.250  -83.968 1.00 9.76   ? 416 GLN A1 CA  1 
ATOM 2995 C C   . GLN A 1 416 ? 72.192  61.621  -84.483 1.00 9.62   ? 416 GLN A1 C   1 
ATOM 2996 O O   . GLN A 1 416 ? 71.191  61.512  -83.776 1.00 10.49  ? 416 GLN A1 O   1 
ATOM 2997 C CB  . GLN A 1 416 ? 74.167  60.043  -84.698 1.00 9.60   ? 416 GLN A1 CB  1 
ATOM 2998 C CG  . GLN A 1 416 ? 73.234  58.923  -84.974 1.00 12.11  ? 416 GLN A1 CG  1 
ATOM 2999 C CD  . GLN A 1 416 ? 73.752  58.054  -86.083 1.00 14.20  ? 416 GLN A1 CD  1 
ATOM 3000 O OE1 . GLN A 1 416 ? 74.559  57.156  -85.860 1.00 14.09  ? 416 GLN A1 OE1 1 
ATOM 3001 N NE2 . GLN A 1 416 ? 73.308  58.327  -87.299 1.00 16.33  ? 416 GLN A1 NE2 1 
ATOM 3002 N N   . ASN A 1 417 ? 72.153  62.073  -85.733 1.00 10.05  ? 417 ASN A1 N   1 
ATOM 3003 C CA  . ASN A 1 417 ? 70.978  62.687  -86.328 1.00 11.04  ? 417 ASN A1 CA  1 
ATOM 3004 C C   . ASN A 1 417 ? 69.887  61.651  -86.573 1.00 12.12  ? 417 ASN A1 C   1 
ATOM 3005 O O   . ASN A 1 417 ? 70.089  60.443  -86.440 1.00 14.32  ? 417 ASN A1 O   1 
ATOM 3006 C CB  . ASN A 1 417 ? 71.358  63.386  -87.627 1.00 11.71  ? 417 ASN A1 CB  1 
ATOM 3007 C CG  . ASN A 1 417 ? 70.518  64.603  -87.899 1.00 12.65  ? 417 ASN A1 CG  1 
ATOM 3008 O OD1 . ASN A 1 417 ? 70.164  65.339  -86.988 1.00 12.46  ? 417 ASN A1 OD1 1 
ATOM 3009 N ND2 . ASN A 1 417 ? 70.184  64.818  -89.162 1.00 15.53  ? 417 ASN A1 ND2 1 
ATOM 3010 N N   . ILE A 1 418 ? 68.702  62.134  -86.947 1.00 11.09  ? 418 ILE A1 N   1 
ATOM 3011 C CA  . ILE A 1 418 ? 67.543  61.264  -87.106 1.00 12.25  ? 418 ILE A1 CA  1 
ATOM 3012 C C   . ILE A 1 418 ? 67.536  60.578  -88.465 1.00 14.48  ? 418 ILE A1 C   1 
ATOM 3013 O O   . ILE A 1 418 ? 66.746  59.646  -88.679 1.00 17.04  ? 418 ILE A1 O   1 
ATOM 3014 C CB  . ILE A 1 418 ? 66.261  62.090  -86.873 1.00 11.75  ? 418 ILE A1 CB  1 
ATOM 3015 C CG1 . ILE A 1 418 ? 65.102  61.215  -86.406 1.00 10.41  ? 418 ILE A1 CG1 1 
ATOM 3016 C CG2 . ILE A 1 418 ? 65.862  62.843  -88.126 1.00 12.36  ? 418 ILE A1 CG2 1 
ATOM 3017 C CD1 . ILE A 1 418 ? 65.292  60.674  -85.018 1.00 9.27   ? 418 ILE A1 CD1 1 
ATOM 3018 N N   . ASN A 1 419 ? 68.410  60.988  -89.386 1.00 16.44  ? 419 ASN A1 N   1 
ATOM 3019 C CA  . ASN A 1 419 ? 68.376  60.427  -90.732 1.00 19.78  ? 419 ASN A1 CA  1 
ATOM 3020 C C   . ASN A 1 419 ? 69.039  59.059  -90.778 1.00 20.35  ? 419 ASN A1 C   1 
ATOM 3021 O O   . ASN A 1 419 ? 68.618  58.196  -91.558 1.00 21.67  ? 419 ASN A1 O   1 
ATOM 3022 C CB  . ASN A 1 419 ? 69.046  61.381  -91.718 1.00 24.28  ? 419 ASN A1 CB  1 
ATOM 3023 C CG  . ASN A 1 419 ? 68.380  62.738  -91.761 1.00 29.54  ? 419 ASN A1 CG  1 
ATOM 3024 O OD1 . ASN A 1 419 ? 69.009  63.734  -92.107 1.00 32.64  ? 419 ASN A1 OD1 1 
ATOM 3025 N ND2 . ASN A 1 419 ? 67.097  62.783  -91.429 1.00 30.89  ? 419 ASN A1 ND2 1 
ATOM 3026 N N   . PHE A 1 420 ? 70.079  58.860  -89.958 1.00 19.18  ? 420 PHE A1 N   1 
ATOM 3027 C CA  . PHE A 1 420 ? 70.755  57.571  -89.758 1.00 17.43  ? 420 PHE A1 CA  1 
ATOM 3028 C C   . PHE A 1 420 ? 71.345  57.012  -91.052 1.00 19.48  ? 420 PHE A1 C   1 
ATOM 3029 O O   . PHE A 1 420 ? 70.894  55.989  -91.568 1.00 20.96  ? 420 PHE A1 O   1 
ATOM 3030 C CB  . PHE A 1 420 ? 69.825  56.551  -89.101 1.00 14.87  ? 420 PHE A1 CB  1 
ATOM 3031 C CG  . PHE A 1 420 ? 70.542  55.497  -88.328 1.00 14.21  ? 420 PHE A1 CG  1 
ATOM 3032 C CD1 . PHE A 1 420 ? 71.030  55.765  -87.066 1.00 13.73  ? 420 PHE A1 CD1 1 
ATOM 3033 C CD2 . PHE A 1 420 ? 70.742  54.241  -88.868 1.00 15.42  ? 420 PHE A1 CD2 1 
ATOM 3034 C CE1 . PHE A 1 420 ? 71.694  54.796  -86.353 1.00 13.35  ? 420 PHE A1 CE1 1 
ATOM 3035 C CE2 . PHE A 1 420 ? 71.406  53.268  -88.159 1.00 13.44  ? 420 PHE A1 CE2 1 
ATOM 3036 C CZ  . PHE A 1 420 ? 71.882  53.546  -86.902 1.00 13.66  ? 420 PHE A1 CZ  1 
ATOM 3037 N N   . ASN A 1 421 ? 72.349  57.698  -91.588 1.00 21.02  ? 421 ASN A1 N   1 
ATOM 3038 C CA  . ASN A 1 421 ? 72.979  57.282  -92.834 1.00 22.99  ? 421 ASN A1 CA  1 
ATOM 3039 C C   . ASN A 1 421 ? 74.213  56.426  -92.562 1.00 22.74  ? 421 ASN A1 C   1 
ATOM 3040 O O   . ASN A 1 421 ? 74.742  56.412  -91.445 1.00 23.78  ? 421 ASN A1 O   1 
ATOM 3041 C CB  . ASN A 1 421 ? 73.345  58.504  -93.669 1.00 26.20  ? 421 ASN A1 CB  1 
ATOM 3042 C CG  . ASN A 1 421 ? 72.133  59.308  -94.077 1.00 29.49  ? 421 ASN A1 CG  1 
ATOM 3043 O OD1 . ASN A 1 421 ? 71.001  58.855  -93.935 1.00 31.42  ? 421 ASN A1 OD1 1 
ATOM 3044 N ND2 . ASN A 1 421 ? 72.364  60.503  -94.600 1.00 29.93  ? 421 ASN A1 ND2 1 
ATOM 3045 N N   . LEU A 1 422 ? 74.660  55.707  -93.592 1.00 22.85  ? 422 LEU A1 N   1 
ATOM 3046 C CA  . LEU A 1 422 ? 75.879  54.910  -93.644 1.00 22.44  ? 422 LEU A1 CA  1 
ATOM 3047 C C   . LEU A 1 422 ? 77.061  55.874  -93.540 1.00 22.80  ? 422 LEU A1 C   1 
ATOM 3048 O O   . LEU A 1 422 ? 76.901  57.027  -93.958 1.00 29.36  ? 422 LEU A1 O   1 
ATOM 3049 C CB  . LEU A 1 422 ? 75.877  54.065  -94.929 1.00 19.56  ? 422 LEU A1 CB  1 
ATOM 3050 C CG  . LEU A 1 422 ? 76.332  54.604  -96.295 1.00 16.38  ? 422 LEU A1 CG  1 
ATOM 3051 C CD1 . LEU A 1 422 ? 76.428  53.463  -97.299 1.00 17.37  ? 422 LEU A1 CD1 1 
ATOM 3052 C CD2 . LEU A 1 422 ? 75.426  55.700  -96.840 1.00 13.02  ? 422 LEU A1 CD2 1 
ATOM 3053 N N   . PRO A 1 423 ? 78.308  55.414  -93.166 1.00 18.78  ? 423 PRO A1 N   1 
ATOM 3054 C CA  . PRO A 1 423 ? 79.048  56.032  -92.047 1.00 15.67  ? 423 PRO A1 CA  1 
ATOM 3055 C C   . PRO A 1 423 ? 78.869  57.521  -91.804 1.00 15.60  ? 423 PRO A1 C   1 
ATOM 3056 O O   . PRO A 1 423 ? 79.048  58.343  -92.705 1.00 18.47  ? 423 PRO A1 O   1 
ATOM 3057 C CB  . PRO A 1 423 ? 80.511  55.734  -92.402 1.00 13.61  ? 423 PRO A1 CB  1 
ATOM 3058 C CG  . PRO A 1 423 ? 80.502  55.363  -93.820 1.00 15.60  ? 423 PRO A1 CG  1 
ATOM 3059 C CD  . PRO A 1 423 ? 79.240  54.632  -93.995 1.00 16.53  ? 423 PRO A1 CD  1 
ATOM 3060 N N   . VAL A 1 424 ? 78.559  57.858  -90.553 1.00 12.98  ? 424 VAL A1 N   1 
ATOM 3061 C CA  . VAL A 1 424 ? 77.976  59.145  -90.199 1.00 10.00  ? 424 VAL A1 CA  1 
ATOM 3062 C C   . VAL A 1 424 ? 79.013  60.257  -90.329 1.00 11.37  ? 424 VAL A1 C   1 
ATOM 3063 O O   . VAL A 1 424 ? 80.195  60.094  -90.010 1.00 12.04  ? 424 VAL A1 O   1 
ATOM 3064 C CB  . VAL A 1 424 ? 77.355  59.056  -88.787 1.00 8.54   ? 424 VAL A1 CB  1 
ATOM 3065 C CG1 . VAL A 1 424 ? 78.389  58.716  -87.727 1.00 8.65   ? 424 VAL A1 CG1 1 
ATOM 3066 C CG2 . VAL A 1 424 ? 76.589  60.310  -88.429 1.00 6.89   ? 424 VAL A1 CG2 1 
ATOM 3067 N N   . THR A 1 425 ? 78.568  61.386  -90.877 1.00 12.81  ? 425 THR A1 N   1 
ATOM 3068 C CA  . THR A 1 425 ? 79.415  62.531  -91.147 1.00 12.68  ? 425 THR A1 CA  1 
ATOM 3069 C C   . THR A 1 425 ? 79.552  63.389  -89.896 1.00 14.45  ? 425 THR A1 C   1 
ATOM 3070 O O   . THR A 1 425 ? 78.870  63.178  -88.897 1.00 14.67  ? 425 THR A1 O   1 
ATOM 3071 C CB  . THR A 1 425 ? 78.841  63.330  -92.306 1.00 12.59  ? 425 THR A1 CB  1 
ATOM 3072 O OG1 . THR A 1 425 ? 77.458  63.586  -92.056 1.00 12.68  ? 425 THR A1 OG1 1 
ATOM 3073 C CG2 . THR A 1 425 ? 78.957  62.532  -93.577 1.00 14.50  ? 425 THR A1 CG2 1 
ATOM 3074 N N   . ASN A 1 426 ? 80.430  64.392  -89.961 1.00 15.89  ? 426 ASN A1 N   1 
ATOM 3075 C CA  . ASN A 1 426 ? 80.796  65.146  -88.766 1.00 15.65  ? 426 ASN A1 CA  1 
ATOM 3076 C C   . ASN A 1 426 ? 79.687  66.075  -88.299 1.00 14.48  ? 426 ASN A1 C   1 
ATOM 3077 O O   . ASN A 1 426 ? 79.545  66.307  -87.096 1.00 12.52  ? 426 ASN A1 O   1 
ATOM 3078 C CB  . ASN A 1 426 ? 82.067  65.946  -89.027 1.00 16.46  ? 426 ASN A1 CB  1 
ATOM 3079 C CG  . ASN A 1 426 ? 82.498  66.757  -87.831 1.00 18.17  ? 426 ASN A1 CG  1 
ATOM 3080 O OD1 . ASN A 1 426 ? 82.272  67.963  -87.773 1.00 19.45  ? 426 ASN A1 OD1 1 
ATOM 3081 N ND2 . ASN A 1 426 ? 83.116  66.098  -86.862 1.00 18.13  ? 426 ASN A1 ND2 1 
ATOM 3082 N N   . ASP A 1 427 ? 78.881  66.599  -89.213 1.00 15.46  ? 427 ASP A1 N   1 
ATOM 3083 C CA  . ASP A 1 427 ? 77.792  67.488  -88.834 1.00 19.18  ? 427 ASP A1 CA  1 
ATOM 3084 C C   . ASP A 1 427 ? 76.519  66.745  -88.482 1.00 17.02  ? 427 ASP A1 C   1 
ATOM 3085 O O   . ASP A 1 427 ? 75.471  67.375  -88.322 1.00 15.08  ? 427 ASP A1 O   1 
ATOM 3086 C CB  . ASP A 1 427 ? 77.520  68.482  -89.960 1.00 26.53  ? 427 ASP A1 CB  1 
ATOM 3087 C CG  . ASP A 1 427 ? 76.953  67.819  -91.194 1.00 32.49  ? 427 ASP A1 CG  1 
ATOM 3088 O OD1 . ASP A 1 427 ? 77.662  66.993  -91.806 1.00 34.36  ? 427 ASP A1 OD1 1 
ATOM 3089 O OD2 . ASP A 1 427 ? 75.803  68.134  -91.564 1.00 36.61  ? 427 ASP A1 OD2 1 
ATOM 3090 N N   . ASN A 1 428 ? 76.584  65.426  -88.354 1.00 16.83  ? 428 ASN A1 N   1 
ATOM 3091 C CA  . ASN A 1 428 ? 75.426  64.616  -88.037 1.00 14.82  ? 428 ASN A1 CA  1 
ATOM 3092 C C   . ASN A 1 428 ? 75.654  63.699  -86.851 1.00 14.89  ? 428 ASN A1 C   1 
ATOM 3093 O O   . ASN A 1 428 ? 74.848  62.792  -86.636 1.00 16.49  ? 428 ASN A1 O   1 
ATOM 3094 C CB  . ASN A 1 428 ? 75.020  63.768  -89.249 1.00 14.56  ? 428 ASN A1 CB  1 
ATOM 3095 C CG  . ASN A 1 428 ? 74.242  64.554  -90.273 1.00 15.68  ? 428 ASN A1 CG  1 
ATOM 3096 O OD1 . ASN A 1 428 ? 74.762  65.479  -90.883 1.00 18.13  ? 428 ASN A1 OD1 1 
ATOM 3097 N ND2 . ASN A 1 428 ? 72.994  64.174  -90.485 1.00 15.44  ? 428 ASN A1 ND2 1 
ATOM 3098 N N   . VAL A 1 429 ? 76.730  63.886  -86.095 1.00 14.73  ? 429 VAL A1 N   1 
ATOM 3099 C CA  . VAL A 1 429 ? 76.995  63.095  -84.905 1.00 14.49  ? 429 VAL A1 CA  1 
ATOM 3100 C C   . VAL A 1 429 ? 77.618  64.009  -83.857 1.00 14.77  ? 429 VAL A1 C   1 
ATOM 3101 O O   . VAL A 1 429 ? 78.398  64.912  -84.172 1.00 14.90  ? 429 VAL A1 O   1 
ATOM 3102 C CB  . VAL A 1 429 ? 77.888  61.862  -85.223 1.00 14.57  ? 429 VAL A1 CB  1 
ATOM 3103 C CG1 . VAL A 1 429 ? 79.234  62.261  -85.785 1.00 13.53  ? 429 VAL A1 CG1 1 
ATOM 3104 C CG2 . VAL A 1 429 ? 78.049  60.945  -84.027 1.00 16.44  ? 429 VAL A1 CG2 1 
ATOM 3105 N N   . LEU A 1 430 ? 77.217  63.813  -82.610 1.00 13.25  ? 430 LEU A1 N   1 
ATOM 3106 C CA  . LEU A 1 430 ? 77.779  64.528  -81.472 1.00 10.17  ? 430 LEU A1 CA  1 
ATOM 3107 C C   . LEU A 1 430 ? 78.620  63.527  -80.690 1.00 10.67  ? 430 LEU A1 C   1 
ATOM 3108 O O   . LEU A 1 430 ? 78.088  62.692  -79.958 1.00 12.11  ? 430 LEU A1 O   1 
ATOM 3109 C CB  . LEU A 1 430 ? 76.676  65.137  -80.616 1.00 8.32   ? 430 LEU A1 CB  1 
ATOM 3110 C CG  . LEU A 1 430 ? 77.035  66.279  -79.673 1.00 7.59   ? 430 LEU A1 CG  1 
ATOM 3111 C CD1 . LEU A 1 430 ? 77.852  67.328  -80.380 1.00 5.61   ? 430 LEU A1 CD1 1 
ATOM 3112 C CD2 . LEU A 1 430 ? 75.774  66.889  -79.129 1.00 6.91   ? 430 LEU A1 CD2 1 
ATOM 3113 N N   . LEU A 1 431 ? 79.924  63.600  -80.870 1.00 10.22  ? 431 LEU A1 N   1 
ATOM 3114 C CA  . LEU A 1 431 ? 80.873  62.722  -80.208 1.00 9.57   ? 431 LEU A1 CA  1 
ATOM 3115 C C   . LEU A 1 431 ? 81.194  63.270  -78.830 1.00 9.72   ? 431 LEU A1 C   1 
ATOM 3116 O O   . LEU A 1 431 ? 80.846  64.404  -78.509 1.00 11.00  ? 431 LEU A1 O   1 
ATOM 3117 C CB  . LEU A 1 431 ? 82.126  62.607  -81.073 1.00 11.09  ? 431 LEU A1 CB  1 
ATOM 3118 C CG  . LEU A 1 431 ? 81.886  62.133  -82.499 1.00 12.79  ? 431 LEU A1 CG  1 
ATOM 3119 C CD1 . LEU A 1 431 ? 83.126  62.309  -83.327 1.00 13.01  ? 431 LEU A1 CD1 1 
ATOM 3120 C CD2 . LEU A 1 431 ? 81.473  60.687  -82.494 1.00 13.62  ? 431 LEU A1 CD2 1 
ATOM 3121 N N   . PRO A 1 432 ? 81.851  62.494  -77.964 1.00 9.89   ? 432 PRO A1 N   1 
ATOM 3122 C CA  . PRO A 1 432 ? 82.409  63.070  -76.739 1.00 10.20  ? 432 PRO A1 CA  1 
ATOM 3123 C C   . PRO A 1 432 ? 83.722  63.810  -76.932 1.00 10.68  ? 432 PRO A1 C   1 
ATOM 3124 O O   . PRO A 1 432 ? 84.350  64.177  -75.937 1.00 12.29  ? 432 PRO A1 O   1 
ATOM 3125 C CB  . PRO A 1 432 ? 82.627  61.840  -75.846 1.00 9.88   ? 432 PRO A1 CB  1 
ATOM 3126 C CG  . PRO A 1 432 ? 81.865  60.786  -76.436 1.00 9.71   ? 432 PRO A1 CG  1 
ATOM 3127 C CD  . PRO A 1 432 ? 81.887  61.028  -77.890 1.00 10.22  ? 432 PRO A1 CD  1 
ATOM 3128 N N   . THR A 1 433 ? 84.162  64.032  -78.166 1.00 11.43  ? 433 THR A1 N   1 
ATOM 3129 C CA  . THR A 1 433 ? 85.399  64.751  -78.411 1.00 10.26  ? 433 THR A1 CA  1 
ATOM 3130 C C   . THR A 1 433 ? 85.185  66.222  -78.715 1.00 11.75  ? 433 THR A1 C   1 
ATOM 3131 O O   . THR A 1 433 ? 86.039  67.041  -78.367 1.00 14.00  ? 433 THR A1 O   1 
ATOM 3132 C CB  . THR A 1 433 ? 86.160  64.116  -79.576 1.00 9.70   ? 433 THR A1 CB  1 
ATOM 3133 O OG1 . THR A 1 433 ? 85.577  64.545  -80.813 1.00 8.77   ? 433 THR A1 OG1 1 
ATOM 3134 C CG2 . THR A 1 433 ? 86.088  62.604  -79.494 1.00 10.26  ? 433 THR A1 CG2 1 
ATOM 3135 N N   . ASP A 1 434 ? 84.072  66.580  -79.343 1.00 11.45  ? 434 ASP A1 N   1 
ATOM 3136 C CA  . ASP A 1 434 ? 83.885  67.959  -79.769 1.00 13.47  ? 434 ASP A1 CA  1 
ATOM 3137 C C   . ASP A 1 434 ? 83.475  68.844  -78.590 1.00 15.48  ? 434 ASP A1 C   1 
ATOM 3138 O O   . ASP A 1 434 ? 82.837  68.367  -77.650 1.00 17.86  ? 434 ASP A1 O   1 
ATOM 3139 C CB  . ASP A 1 434 ? 82.856  68.032  -80.901 1.00 14.75  ? 434 ASP A1 CB  1 
ATOM 3140 C CG  . ASP A 1 434 ? 81.641  67.166  -80.661 1.00 15.20  ? 434 ASP A1 CG  1 
ATOM 3141 O OD1 . ASP A 1 434 ? 81.200  66.520  -81.632 1.00 17.25  ? 434 ASP A1 OD1 1 
ATOM 3142 O OD2 . ASP A 1 434 ? 81.106  67.142  -79.538 1.00 15.94  ? 434 ASP A1 OD2 1 
ATOM 3143 N N   . PRO A 1 435 ? 83.858  70.121  -78.598 1.00 17.48  ? 435 PRO A1 N   1 
ATOM 3144 C CA  . PRO A 1 435 ? 83.526  71.001  -77.474 1.00 18.53  ? 435 PRO A1 CA  1 
ATOM 3145 C C   . PRO A 1 435 ? 82.052  71.365  -77.429 1.00 18.51  ? 435 PRO A1 C   1 
ATOM 3146 O O   . PRO A 1 435 ? 81.396  71.522  -78.460 1.00 20.70  ? 435 PRO A1 O   1 
ATOM 3147 C CB  . PRO A 1 435 ? 84.382  72.243  -77.745 1.00 18.47  ? 435 PRO A1 CB  1 
ATOM 3148 C CG  . PRO A 1 435 ? 84.613  72.224  -79.192 1.00 18.44  ? 435 PRO A1 CG  1 
ATOM 3149 C CD  . PRO A 1 435 ? 84.767  70.788  -79.545 1.00 18.54  ? 435 PRO A1 CD  1 
ATOM 3150 N N   . ILE A 1 436 ? 81.541  71.502  -76.213 1.00 17.20  ? 436 ILE A1 N   1 
ATOM 3151 C CA  . ILE A 1 436 ? 80.187  71.980  -75.968 1.00 15.65  ? 436 ILE A1 CA  1 
ATOM 3152 C C   . ILE A 1 436 ? 80.292  73.262  -75.160 1.00 15.80  ? 436 ILE A1 C   1 
ATOM 3153 O O   . ILE A 1 436 ? 80.899  73.278  -74.083 1.00 15.49  ? 436 ILE A1 O   1 
ATOM 3154 C CB  . ILE A 1 436 ? 79.337  70.921  -75.253 1.00 15.24  ? 436 ILE A1 CB  1 
ATOM 3155 C CG1 . ILE A 1 436 ? 78.844  69.890  -76.269 1.00 16.49  ? 436 ILE A1 CG1 1 
ATOM 3156 C CG2 . ILE A 1 436 ? 78.162  71.545  -74.514 1.00 14.86  ? 436 ILE A1 CG2 1 
ATOM 3157 C CD1 . ILE A 1 436 ? 77.755  70.380  -77.185 1.00 17.51  ? 436 ILE A1 CD1 1 
ATOM 3158 N N   . GLY A 1 437 ? 79.732  74.343  -75.693 1.00 15.64  ? 437 GLY A1 N   1 
ATOM 3159 C CA  . GLY A 1 437 ? 79.890  75.647  -75.093 1.00 15.71  ? 437 GLY A1 CA  1 
ATOM 3160 C C   . GLY A 1 437 ? 81.210  76.320  -75.380 1.00 16.08  ? 437 GLY A1 C   1 
ATOM 3161 O O   . GLY A 1 437 ? 81.462  77.403  -74.843 1.00 16.36  ? 437 GLY A1 O   1 
ATOM 3162 N N   . GLY A 1 438 ? 82.056  75.719  -76.213 1.00 14.88  ? 438 GLY A1 N   1 
ATOM 3163 C CA  . GLY A 1 438 ? 83.366  76.236  -76.515 1.00 14.17  ? 438 GLY A1 CA  1 
ATOM 3164 C C   . GLY A 1 438 ? 84.478  75.645  -75.678 1.00 14.39  ? 438 GLY A1 C   1 
ATOM 3165 O O   . GLY A 1 438 ? 85.651  75.825  -76.016 1.00 16.97  ? 438 GLY A1 O   1 
ATOM 3166 N N   . LYS A 1 439 ? 84.141  74.940  -74.603 1.00 13.29  ? 439 LYS A1 N   1 
ATOM 3167 C CA  . LYS A 1 439 ? 85.141  74.397  -73.693 1.00 10.73  ? 439 LYS A1 CA  1 
ATOM 3168 C C   . LYS A 1 439 ? 85.659  73.087  -74.264 1.00 11.74  ? 439 LYS A1 C   1 
ATOM 3169 O O   . LYS A 1 439 ? 84.880  72.171  -74.528 1.00 10.73  ? 439 LYS A1 O   1 
ATOM 3170 C CB  . LYS A 1 439 ? 84.546  74.194  -72.304 1.00 7.78   ? 439 LYS A1 CB  1 
ATOM 3171 C CG  . LYS A 1 439 ? 83.752  75.373  -71.782 1.00 4.81   ? 439 LYS A1 CG  1 
ATOM 3172 C CD  . LYS A 1 439 ? 84.599  76.624  -71.732 1.00 2.50   ? 439 LYS A1 CD  1 
ATOM 3173 C CE  . LYS A 1 439 ? 83.759  77.848  -71.464 1.00 2.07   ? 439 LYS A1 CE  1 
ATOM 3174 N NZ  . LYS A 1 439 ? 83.285  77.900  -70.060 1.00 4.60   ? 439 LYS A1 NZ  1 
ATOM 3175 N N   . THR A 1 440 ? 86.974  72.991  -74.460 1.00 14.31  ? 440 THR A1 N   1 
ATOM 3176 C CA  . THR A 1 440 ? 87.549  71.774  -75.018 1.00 16.59  ? 440 THR A1 CA  1 
ATOM 3177 C C   . THR A 1 440 ? 87.546  70.621  -74.028 1.00 17.07  ? 440 THR A1 C   1 
ATOM 3178 O O   . THR A 1 440 ? 87.611  69.463  -74.448 1.00 20.55  ? 440 THR A1 O   1 
ATOM 3179 C CB  . THR A 1 440 ? 88.974  72.027  -75.493 1.00 16.25  ? 440 THR A1 CB  1 
ATOM 3180 O OG1 . THR A 1 440 ? 89.779  72.428  -74.379 1.00 17.74  ? 440 THR A1 OG1 1 
ATOM 3181 C CG2 . THR A 1 440 ? 88.992  73.119  -76.543 1.00 18.45  ? 440 THR A1 CG2 1 
ATOM 3182 N N   . GLY A 1 441 ? 87.479  70.904  -72.735 1.00 15.92  ? 441 GLY A1 N   1 
ATOM 3183 C CA  . GLY A 1 441 ? 87.395  69.866  -71.738 1.00 15.07  ? 441 GLY A1 CA  1 
ATOM 3184 C C   . GLY A 1 441 ? 85.996  69.512  -71.321 1.00 14.08  ? 441 GLY A1 C   1 
ATOM 3185 O O   . GLY A 1 441 ? 85.812  68.699  -70.413 1.00 13.77  ? 441 GLY A1 O   1 
ATOM 3186 N N   . ILE A 1 442 ? 84.992  70.101  -71.960 1.00 12.33  ? 442 ILE A1 N   1 
ATOM 3187 C CA  . ILE A 1 442 ? 83.593  69.855  -71.648 1.00 10.69  ? 442 ILE A1 CA  1 
ATOM 3188 C C   . ILE A 1 442 ? 82.896  69.449  -72.935 1.00 12.10  ? 442 ILE A1 C   1 
ATOM 3189 O O   . ILE A 1 442 ? 82.845  70.229  -73.890 1.00 13.25  ? 442 ILE A1 O   1 
ATOM 3190 C CB  . ILE A 1 442 ? 82.920  71.089  -71.031 1.00 9.24   ? 442 ILE A1 CB  1 
ATOM 3191 C CG1 . ILE A 1 442 ? 83.545  71.422  -69.679 1.00 9.71   ? 442 ILE A1 CG1 1 
ATOM 3192 C CG2 . ILE A 1 442 ? 81.438  70.860  -70.879 1.00 9.12   ? 442 ILE A1 CG2 1 
ATOM 3193 C CD1 . ILE A 1 442 ? 83.344  70.371  -68.649 1.00 9.16   ? 442 ILE A1 CD1 1 
ATOM 3194 N N   . ASN A 1 443 ? 82.375  68.233  -72.966 1.00 12.79  ? 443 ASN A1 N   1 
ATOM 3195 C CA  . ASN A 1 443 ? 81.590  67.715  -74.076 1.00 11.95  ? 443 ASN A1 CA  1 
ATOM 3196 C C   . ASN A 1 443 ? 80.130  67.611  -73.657 1.00 11.61  ? 443 ASN A1 C   1 
ATOM 3197 O O   . ASN A 1 443 ? 79.739  68.070  -72.586 1.00 11.73  ? 443 ASN A1 O   1 
ATOM 3198 C CB  . ASN A 1 443 ? 82.146  66.374  -74.537 1.00 12.58  ? 443 ASN A1 CB  1 
ATOM 3199 C CG  . ASN A 1 443 ? 82.551  65.509  -73.391 1.00 13.37  ? 443 ASN A1 CG  1 
ATOM 3200 O OD1 . ASN A 1 443 ? 82.324  65.851  -72.241 1.00 14.15  ? 443 ASN A1 OD1 1 
ATOM 3201 N ND2 . ASN A 1 443 ? 83.174  64.389  -73.690 1.00 14.87  ? 443 ASN A1 ND2 1 
ATOM 3202 N N   . TYR A 1 444 ? 79.311  67.008  -74.522 1.00 11.20  ? 444 TYR A1 N   1 
ATOM 3203 C CA  . TYR A 1 444 ? 77.878  66.966  -74.255 1.00 10.90  ? 444 TYR A1 CA  1 
ATOM 3204 C C   . TYR A 1 444 ? 77.541  65.981  -73.157 1.00 10.46  ? 444 TYR A1 C   1 
ATOM 3205 O O   . TYR A 1 444 ? 76.467  66.076  -72.566 1.00 10.79  ? 444 TYR A1 O   1 
ATOM 3206 C CB  . TYR A 1 444 ? 77.099  66.587  -75.518 1.00 11.59  ? 444 TYR A1 CB  1 
ATOM 3207 C CG  . TYR A 1 444 ? 77.028  65.099  -75.770 1.00 13.04  ? 444 TYR A1 CG  1 
ATOM 3208 C CD1 . TYR A 1 444 ? 78.096  64.416  -76.319 1.00 14.40  ? 444 TYR A1 CD1 1 
ATOM 3209 C CD2 . TYR A 1 444 ? 75.865  64.388  -75.498 1.00 13.51  ? 444 TYR A1 CD2 1 
ATOM 3210 C CE1 . TYR A 1 444 ? 78.024  63.066  -76.536 1.00 14.86  ? 444 TYR A1 CE1 1 
ATOM 3211 C CE2 . TYR A 1 444 ? 75.795  63.050  -75.707 1.00 14.81  ? 444 TYR A1 CE2 1 
ATOM 3212 C CZ  . TYR A 1 444 ? 76.867  62.397  -76.232 1.00 15.63  ? 444 TYR A1 CZ  1 
ATOM 3213 O OH  . TYR A 1 444 ? 76.767  61.055  -76.446 1.00 18.21  ? 444 TYR A1 OH  1 
ATOM 3214 N N   . THR A 1 445 ? 78.402  65.007  -72.911 1.00 10.43  ? 445 THR A1 N   1 
ATOM 3215 C CA  . THR A 1 445 ? 78.098  63.973  -71.941 1.00 8.86   ? 445 THR A1 CA  1 
ATOM 3216 C C   . THR A 1 445 ? 78.406  64.411  -70.523 1.00 8.70   ? 445 THR A1 C   1 
ATOM 3217 O O   . THR A 1 445 ? 78.066  63.696  -69.580 1.00 8.66   ? 445 THR A1 O   1 
ATOM 3218 C CB  . THR A 1 445 ? 78.860  62.699  -72.284 1.00 7.45   ? 445 THR A1 CB  1 
ATOM 3219 O OG1 . THR A 1 445 ? 78.604  61.717  -71.281 1.00 8.04   ? 445 THR A1 OG1 1 
ATOM 3220 C CG2 . THR A 1 445 ? 80.331  62.976  -72.335 1.00 7.17   ? 445 THR A1 CG2 1 
ATOM 3221 N N   . ASN A 1 446 ? 79.032  65.572  -70.360 1.00 9.90   ? 446 ASN A1 N   1 
ATOM 3222 C CA  . ASN A 1 446 ? 79.177  66.201  -69.061 1.00 10.48  ? 446 ASN A1 CA  1 
ATOM 3223 C C   . ASN A 1 446 ? 77.885  66.848  -68.595 1.00 9.10   ? 446 ASN A1 C   1 
ATOM 3224 O O   . ASN A 1 446 ? 77.741  67.111  -67.402 1.00 10.07  ? 446 ASN A1 O   1 
ATOM 3225 C CB  . ASN A 1 446 ? 80.283  67.251  -69.123 1.00 10.86  ? 446 ASN A1 CB  1 
ATOM 3226 C CG  . ASN A 1 446 ? 81.632  66.691  -68.777 1.00 10.28  ? 446 ASN A1 CG  1 
ATOM 3227 O OD1 . ASN A 1 446 ? 81.993  66.604  -67.609 1.00 10.49  ? 446 ASN A1 OD1 1 
ATOM 3228 N ND2 . ASN A 1 446 ? 82.390  66.309  -69.786 1.00 10.14  ? 446 ASN A1 ND2 1 
ATOM 3229 N N   . ILE A 1 447 ? 76.957  67.129  -69.511 1.00 8.58   ? 447 ILE A1 N   1 
ATOM 3230 C CA  . ILE A 1 447 ? 75.657  67.692  -69.165 1.00 8.38   ? 447 ILE A1 CA  1 
ATOM 3231 C C   . ILE A 1 447 ? 74.509  66.768  -69.545 1.00 9.40   ? 447 ILE A1 C   1 
ATOM 3232 O O   . ILE A 1 447 ? 73.347  67.200  -69.523 1.00 12.03  ? 447 ILE A1 O   1 
ATOM 3233 C CB  . ILE A 1 447 ? 75.449  69.071  -69.825 1.00 6.76   ? 447 ILE A1 CB  1 
ATOM 3234 C CG1 . ILE A 1 447 ? 75.458  68.937  -71.345 1.00 6.20   ? 447 ILE A1 CG1 1 
ATOM 3235 C CG2 . ILE A 1 447 ? 76.523  70.029  -69.392 1.00 5.11   ? 447 ILE A1 CG2 1 
ATOM 3236 C CD1 . ILE A 1 447 ? 75.394  70.237  -72.090 1.00 7.64   ? 447 ILE A1 CD1 1 
ATOM 3237 N N   . PHE A 1 448 ? 74.791  65.515  -69.870 1.00 10.26  ? 448 PHE A1 N   1 
ATOM 3238 C CA  . PHE A 1 448 ? 73.798  64.617  -70.439 1.00 9.54   ? 448 PHE A1 CA  1 
ATOM 3239 C C   . PHE A 1 448 ? 73.067  63.882  -69.328 1.00 11.19  ? 448 PHE A1 C   1 
ATOM 3240 O O   . PHE A 1 448 ? 73.691  63.403  -68.380 1.00 12.27  ? 448 PHE A1 O   1 
ATOM 3241 C CB  . PHE A 1 448 ? 74.485  63.627  -71.367 1.00 8.07   ? 448 PHE A1 CB  1 
ATOM 3242 C CG  . PHE A 1 448 ? 73.564  62.926  -72.292 1.00 6.02   ? 448 PHE A1 CG  1 
ATOM 3243 C CD1 . PHE A 1 448 ? 72.687  63.638  -73.084 1.00 4.35   ? 448 PHE A1 CD1 1 
ATOM 3244 C CD2 . PHE A 1 448 ? 73.588  61.555  -72.382 1.00 5.89   ? 448 PHE A1 CD2 1 
ATOM 3245 C CE1 . PHE A 1 448 ? 71.838  62.991  -73.938 1.00 4.99   ? 448 PHE A1 CE1 1 
ATOM 3246 C CE2 . PHE A 1 448 ? 72.752  60.904  -73.239 1.00 6.34   ? 448 PHE A1 CE2 1 
ATOM 3247 C CZ  . PHE A 1 448 ? 71.873  61.622  -74.020 1.00 6.62   ? 448 PHE A1 CZ  1 
ATOM 3248 N N   . ASN A 1 449 ? 71.750  63.788  -69.448 1.00 11.52  ? 449 ASN A1 N   1 
ATOM 3249 C CA  . ASN A 1 449 ? 70.919  63.063  -68.504 1.00 9.31   ? 449 ASN A1 CA  1 
ATOM 3250 C C   . ASN A 1 449 ? 69.953  62.190  -69.282 1.00 8.79   ? 449 ASN A1 C   1 
ATOM 3251 O O   . ASN A 1 449 ? 69.193  62.696  -70.111 1.00 7.67   ? 449 ASN A1 O   1 
ATOM 3252 C CB  . ASN A 1 449 ? 70.152  64.030  -67.604 1.00 9.32   ? 449 ASN A1 CB  1 
ATOM 3253 C CG  . ASN A 1 449 ? 69.385  63.330  -66.516 1.00 8.34   ? 449 ASN A1 CG  1 
ATOM 3254 O OD1 . ASN A 1 449 ? 69.771  62.264  -66.058 1.00 9.44   ? 449 ASN A1 OD1 1 
ATOM 3255 N ND2 . ASN A 1 449 ? 68.285  63.924  -66.099 1.00 8.09   ? 449 ASN A1 ND2 1 
ATOM 3256 N N   . THR A 1 450 ? 69.988  60.883  -69.036 1.00 7.64   ? 450 THR A1 N   1 
ATOM 3257 C CA  . THR A 1 450 ? 68.986  59.985  -69.593 1.00 6.71   ? 450 THR A1 CA  1 
ATOM 3258 C C   . THR A 1 450 ? 68.231  59.222  -68.518 1.00 8.63   ? 450 THR A1 C   1 
ATOM 3259 O O   . THR A 1 450 ? 67.948  58.038  -68.694 1.00 10.17  ? 450 THR A1 O   1 
ATOM 3260 C CB  . THR A 1 450 ? 69.593  58.996  -70.582 1.00 4.64   ? 450 THR A1 CB  1 
ATOM 3261 O OG1 . THR A 1 450 ? 70.883  58.583  -70.130 1.00 2.00   ? 450 THR A1 OG1 1 
ATOM 3262 C CG2 . THR A 1 450 ? 69.694  59.609  -71.943 1.00 2.10   ? 450 THR A1 CG2 1 
ATOM 3263 N N   . TYR A 1 451 ? 67.906  59.868  -67.408 1.00 8.71   ? 451 TYR A1 N   1 
ATOM 3264 C CA  . TYR A 1 451 ? 66.909  59.297  -66.527 1.00 8.54   ? 451 TYR A1 CA  1 
ATOM 3265 C C   . TYR A 1 451 ? 65.551  59.381  -67.202 1.00 9.68   ? 451 TYR A1 C   1 
ATOM 3266 O O   . TYR A 1 451 ? 65.130  60.439  -67.671 1.00 13.43  ? 451 TYR A1 O   1 
ATOM 3267 C CB  . TYR A 1 451 ? 66.883  60.022  -65.190 1.00 7.14   ? 451 TYR A1 CB  1 
ATOM 3268 C CG  . TYR A 1 451 ? 66.035  59.322  -64.172 1.00 6.64   ? 451 TYR A1 CG  1 
ATOM 3269 C CD1 . TYR A 1 451 ? 66.452  58.136  -63.601 1.00 5.72   ? 451 TYR A1 CD1 1 
ATOM 3270 C CD2 . TYR A 1 451 ? 64.806  59.832  -63.801 1.00 7.14   ? 451 TYR A1 CD2 1 
ATOM 3271 C CE1 . TYR A 1 451 ? 65.675  57.483  -62.682 1.00 5.98   ? 451 TYR A1 CE1 1 
ATOM 3272 C CE2 . TYR A 1 451 ? 64.020  59.187  -62.883 1.00 6.36   ? 451 TYR A1 CE2 1 
ATOM 3273 C CZ  . TYR A 1 451 ? 64.459  58.016  -62.328 1.00 6.42   ? 451 TYR A1 CZ  1 
ATOM 3274 O OH  . TYR A 1 451 ? 63.676  57.374  -61.407 1.00 5.80   ? 451 TYR A1 OH  1 
ATOM 3275 N N   . GLY A 1 452 ? 64.874  58.245  -67.278 1.00 9.80   ? 452 GLY A1 N   1 
ATOM 3276 C CA  . GLY A 1 452 ? 63.616  58.168  -67.966 1.00 7.79   ? 452 GLY A1 CA  1 
ATOM 3277 C C   . GLY A 1 452 ? 62.662  57.233  -67.267 1.00 8.11   ? 452 GLY A1 C   1 
ATOM 3278 O O   . GLY A 1 452 ? 62.925  56.756  -66.163 1.00 10.24  ? 452 GLY A1 O   1 
ATOM 3279 N N   . PRO A 1 453 ? 61.513  56.971  -67.887 1.00 6.34   ? 453 PRO A1 N   1 
ATOM 3280 C CA  . PRO A 1 453 ? 60.575  56.011  -67.300 1.00 6.05   ? 453 PRO A1 CA  1 
ATOM 3281 C C   . PRO A 1 453 ? 60.972  54.577  -67.538 1.00 8.27   ? 453 PRO A1 C   1 
ATOM 3282 O O   . PRO A 1 453 ? 60.368  53.677  -66.949 1.00 8.52   ? 453 PRO A1 O   1 
ATOM 3283 C CB  . PRO A 1 453 ? 59.249  56.344  -67.993 1.00 4.64   ? 453 PRO A1 CB  1 
ATOM 3284 C CG  . PRO A 1 453 ? 59.492  57.608  -68.739 1.00 3.45   ? 453 PRO A1 CG  1 
ATOM 3285 C CD  . PRO A 1 453 ? 60.930  57.642  -69.053 1.00 4.13   ? 453 PRO A1 CD  1 
ATOM 3286 N N   . LEU A 1 454 ? 61.960  54.336  -68.389 1.00 10.31  ? 454 LEU A1 N   1 
ATOM 3287 C CA  . LEU A 1 454 ? 62.441  53.001  -68.691 1.00 8.15   ? 454 LEU A1 CA  1 
ATOM 3288 C C   . LEU A 1 454 ? 63.763  52.685  -68.020 1.00 8.08   ? 454 LEU A1 C   1 
ATOM 3289 O O   . LEU A 1 454 ? 64.370  51.667  -68.353 1.00 8.60   ? 454 LEU A1 O   1 
ATOM 3290 C CB  . LEU A 1 454 ? 62.599  52.838  -70.198 1.00 6.85   ? 454 LEU A1 CB  1 
ATOM 3291 C CG  . LEU A 1 454 ? 61.436  53.251  -71.084 1.00 6.12   ? 454 LEU A1 CG  1 
ATOM 3292 C CD1 . LEU A 1 454 ? 61.835  53.092  -72.510 1.00 6.02   ? 454 LEU A1 CD1 1 
ATOM 3293 C CD2 . LEU A 1 454 ? 60.233  52.403  -70.795 1.00 7.11   ? 454 LEU A1 CD2 1 
ATOM 3294 N N   . THR A 1 455 ? 64.235  53.523  -67.107 1.00 7.22   ? 455 THR A1 N   1 
ATOM 3295 C CA  . THR A 1 455 ? 65.514  53.302  -66.453 1.00 5.85   ? 455 THR A1 CA  1 
ATOM 3296 C C   . THR A 1 455 ? 65.315  52.419  -65.231 1.00 5.69   ? 455 THR A1 C   1 
ATOM 3297 O O   . THR A 1 455 ? 64.541  52.756  -64.331 1.00 8.58   ? 455 THR A1 O   1 
ATOM 3298 C CB  . THR A 1 455 ? 66.178  54.625  -66.081 1.00 3.94   ? 455 THR A1 CB  1 
ATOM 3299 O OG1 . THR A 1 455 ? 66.725  55.221  -67.260 1.00 4.95   ? 455 THR A1 OG1 1 
ATOM 3300 C CG2 . THR A 1 455 ? 67.295  54.406  -65.098 1.00 3.32   ? 455 THR A1 CG2 1 
ATOM 3301 N N   . ALA A 1 456 ? 65.990  51.275  -65.224 1.00 4.19   ? 456 ALA A1 N   1 
ATOM 3302 C CA  . ALA A 1 456 ? 66.056  50.379  -64.084 1.00 2.79   ? 456 ALA A1 CA  1 
ATOM 3303 C C   . ALA A 1 456 ? 67.460  50.416  -63.512 1.00 3.15   ? 456 ALA A1 C   1 
ATOM 3304 O O   . ALA A 1 456 ? 68.440  50.356  -64.256 1.00 5.68   ? 456 ALA A1 O   1 
ATOM 3305 C CB  . ALA A 1 456 ? 65.704  48.951  -64.488 1.00 2.00   ? 456 ALA A1 CB  1 
ATOM 3306 N N   . LEU A 1 457 ? 67.561  50.509  -62.195 1.00 3.37   ? 457 LEU A1 N   1 
ATOM 3307 C CA  . LEU A 1 457 ? 68.862  50.594  -61.552 1.00 5.28   ? 457 LEU A1 CA  1 
ATOM 3308 C C   . LEU A 1 457 ? 68.784  49.885  -60.213 1.00 6.49   ? 457 LEU A1 C   1 
ATOM 3309 O O   . LEU A 1 457 ? 67.702  49.615  -59.693 1.00 7.42   ? 457 LEU A1 O   1 
ATOM 3310 C CB  . LEU A 1 457 ? 69.332  52.045  -61.397 1.00 5.86   ? 457 LEU A1 CB  1 
ATOM 3311 C CG  . LEU A 1 457 ? 68.643  53.015  -60.441 1.00 7.11   ? 457 LEU A1 CG  1 
ATOM 3312 C CD1 . LEU A 1 457 ? 69.624  54.087  -60.061 1.00 7.57   ? 457 LEU A1 CD1 1 
ATOM 3313 C CD2 . LEU A 1 457 ? 67.447  53.665  -61.092 1.00 8.85   ? 457 LEU A1 CD2 1 
ATOM 3314 N N   . ASN A 1 458 ? 69.951  49.565  -59.673 1.00 7.08   ? 458 ASN A1 N   1 
ATOM 3315 C CA  . ASN A 1 458 ? 70.076  48.771  -58.466 1.00 7.25   ? 458 ASN A1 CA  1 
ATOM 3316 C C   . ASN A 1 458 ? 70.439  49.647  -57.278 1.00 9.35   ? 458 ASN A1 C   1 
ATOM 3317 O O   . ASN A 1 458 ? 70.930  50.768  -57.424 1.00 12.49  ? 458 ASN A1 O   1 
ATOM 3318 C CB  . ASN A 1 458 ? 71.137  47.686  -58.633 1.00 6.75   ? 458 ASN A1 CB  1 
ATOM 3319 C CG  . ASN A 1 458 ? 70.618  46.474  -59.349 1.00 8.83   ? 458 ASN A1 CG  1 
ATOM 3320 O OD1 . ASN A 1 458 ? 70.075  45.564  -58.732 1.00 11.61  ? 458 ASN A1 OD1 1 
ATOM 3321 N ND2 . ASN A 1 458 ? 70.787  46.446  -60.658 1.00 6.70   ? 458 ASN A1 ND2 1 
ATOM 3322 N N   . ASN A 1 459 ? 70.197  49.106  -56.093 1.00 8.34   ? 459 ASN A1 N   1 
ATOM 3323 C CA  . ASN A 1 459 ? 70.563  49.781  -54.863 1.00 8.28   ? 459 ASN A1 CA  1 
ATOM 3324 C C   . ASN A 1 459 ? 72.073  49.724  -54.664 1.00 9.89   ? 459 ASN A1 C   1 
ATOM 3325 O O   . ASN A 1 459 ? 72.786  48.965  -55.322 1.00 14.32  ? 459 ASN A1 O   1 
ATOM 3326 C CB  . ASN A 1 459 ? 69.851  49.139  -53.677 1.00 8.04   ? 459 ASN A1 CB  1 
ATOM 3327 C CG  . ASN A 1 459 ? 69.619  50.105  -52.554 1.00 9.11   ? 459 ASN A1 CG  1 
ATOM 3328 O OD1 . ASN A 1 459 ? 69.993  51.268  -52.638 1.00 11.28  ? 459 ASN A1 OD1 1 
ATOM 3329 N ND2 . ASN A 1 459 ? 69.004  49.630  -51.487 1.00 10.08  ? 459 ASN A1 ND2 1 
ATOM 3330 N N   . VAL A 1 460 ? 72.556  50.535  -53.736 1.00 8.74   ? 460 VAL A1 N   1 
ATOM 3331 C CA  . VAL A 1 460 ? 74.003  50.591  -53.504 1.00 6.48   ? 460 VAL A1 CA  1 
ATOM 3332 C C   . VAL A 1 460 ? 74.432  49.375  -52.692 1.00 6.00   ? 460 VAL A1 C   1 
ATOM 3333 O O   . VAL A 1 460 ? 73.658  48.890  -51.848 1.00 8.97   ? 460 VAL A1 O   1 
ATOM 3334 C CB  . VAL A 1 460 ? 74.379  51.894  -52.805 1.00 7.70   ? 460 VAL A1 CB  1 
ATOM 3335 C CG1 . VAL A 1 460 ? 74.238  53.039  -53.776 1.00 9.76   ? 460 VAL A1 CG1 1 
ATOM 3336 C CG2 . VAL A 1 460 ? 73.508  52.132  -51.593 1.00 9.12   ? 460 VAL A1 CG2 1 
ATOM 3337 N N   . PRO A 1 461 ? 75.614  48.824  -52.935 1.00 4.81   ? 461 PRO A1 N   1 
ATOM 3338 C CA  . PRO A 1 461 ? 76.071  47.685  -52.164 1.00 4.54   ? 461 PRO A1 CA  1 
ATOM 3339 C C   . PRO A 1 461 ? 76.559  48.120  -50.798 1.00 6.16   ? 461 PRO A1 C   1 
ATOM 3340 O O   . PRO A 1 461 ? 76.824  49.310  -50.577 1.00 8.71   ? 461 PRO A1 O   1 
ATOM 3341 C CB  . PRO A 1 461 ? 77.225  47.141  -53.008 1.00 3.64   ? 461 PRO A1 CB  1 
ATOM 3342 C CG  . PRO A 1 461 ? 77.717  48.317  -53.704 1.00 2.64   ? 461 PRO A1 CG  1 
ATOM 3343 C CD  . PRO A 1 461 ? 76.533  49.127  -54.039 1.00 3.42   ? 461 PRO A1 CD  1 
ATOM 3344 N N   . PRO A 1 462 ? 76.663  47.195  -49.849 1.00 5.80   ? 462 PRO A1 N   1 
ATOM 3345 C CA  . PRO A 1 462 ? 77.352  47.507  -48.598 1.00 6.03   ? 462 PRO A1 CA  1 
ATOM 3346 C C   . PRO A 1 462 ? 78.834  47.734  -48.837 1.00 7.08   ? 462 PRO A1 C   1 
ATOM 3347 O O   . PRO A 1 462 ? 79.418  47.200  -49.779 1.00 9.18   ? 462 PRO A1 O   1 
ATOM 3348 C CB  . PRO A 1 462 ? 77.106  46.262  -47.745 1.00 4.38   ? 462 PRO A1 CB  1 
ATOM 3349 C CG  . PRO A 1 462 ? 75.859  45.694  -48.284 1.00 3.26   ? 462 PRO A1 CG  1 
ATOM 3350 C CD  . PRO A 1 462 ? 75.900  45.943  -49.750 1.00 4.46   ? 462 PRO A1 CD  1 
ATOM 3351 N N   . VAL A 1 463 ? 79.440  48.562  -47.998 1.00 7.39   ? 463 VAL A1 N   1 
ATOM 3352 C CA  . VAL A 1 463 ? 80.869  48.828  -48.074 1.00 6.44   ? 463 VAL A1 CA  1 
ATOM 3353 C C   . VAL A 1 463 ? 81.477  48.401  -46.754 1.00 6.26   ? 463 VAL A1 C   1 
ATOM 3354 O O   . VAL A 1 463 ? 81.428  49.146  -45.772 1.00 7.99   ? 463 VAL A1 O   1 
ATOM 3355 C CB  . VAL A 1 463 ? 81.179  50.296  -48.369 1.00 5.57   ? 463 VAL A1 CB  1 
ATOM 3356 C CG1 . VAL A 1 463 ? 82.659  50.461  -48.583 1.00 5.84   ? 463 VAL A1 CG1 1 
ATOM 3357 C CG2 . VAL A 1 463 ? 80.424  50.764  -49.587 1.00 6.29   ? 463 VAL A1 CG2 1 
ATOM 3358 N N   . TYR A 1 464 ? 82.039  47.208  -46.724 1.00 6.50   ? 464 TYR A1 N   1 
ATOM 3359 C CA  . TYR A 1 464 ? 82.719  46.791  -45.513 1.00 5.31   ? 464 TYR A1 CA  1 
ATOM 3360 C C   . TYR A 1 464 ? 84.098  47.434  -45.452 1.00 4.86   ? 464 TYR A1 C   1 
ATOM 3361 O O   . TYR A 1 464 ? 84.768  47.543  -46.474 1.00 5.14   ? 464 TYR A1 O   1 
ATOM 3362 C CB  . TYR A 1 464 ? 82.858  45.278  -45.477 1.00 4.84   ? 464 TYR A1 CB  1 
ATOM 3363 C CG  . TYR A 1 464 ? 83.458  44.753  -44.205 1.00 4.40   ? 464 TYR A1 CG  1 
ATOM 3364 C CD1 . TYR A 1 464 ? 84.770  44.318  -44.162 1.00 3.32   ? 464 TYR A1 CD1 1 
ATOM 3365 C CD2 . TYR A 1 464 ? 82.710  44.696  -43.050 1.00 4.49   ? 464 TYR A1 CD2 1 
ATOM 3366 C CE1 . TYR A 1 464 ? 85.309  43.851  -43.009 1.00 3.12   ? 464 TYR A1 CE1 1 
ATOM 3367 C CE2 . TYR A 1 464 ? 83.242  44.237  -41.898 1.00 3.04   ? 464 TYR A1 CE2 1 
ATOM 3368 C CZ  . TYR A 1 464 ? 84.535  43.819  -41.877 1.00 3.02   ? 464 TYR A1 CZ  1 
ATOM 3369 O OH  . TYR A 1 464 ? 85.058  43.360  -40.703 1.00 3.43   ? 464 TYR A1 OH  1 
ATOM 3370 N N   . PRO A 1 465 ? 84.562  47.919  -44.297 1.00 3.97   ? 465 PRO A1 N   1 
ATOM 3371 C CA  . PRO A 1 465 ? 83.885  48.080  -43.011 1.00 3.78   ? 465 PRO A1 CA  1 
ATOM 3372 C C   . PRO A 1 465 ? 83.314  49.461  -42.754 1.00 4.37   ? 465 PRO A1 C   1 
ATOM 3373 O O   . PRO A 1 465 ? 82.850  49.697  -41.654 1.00 4.26   ? 465 PRO A1 O   1 
ATOM 3374 C CB  . PRO A 1 465 ? 85.000  47.800  -42.021 1.00 2.25   ? 465 PRO A1 CB  1 
ATOM 3375 C CG  . PRO A 1 465 ? 86.180  48.302  -42.685 1.00 2.10   ? 465 PRO A1 CG  1 
ATOM 3376 C CD  . PRO A 1 465 ? 86.020  47.993  -44.135 1.00 2.94   ? 465 PRO A1 CD  1 
ATOM 3377 N N   . ASN A 1 466 ? 83.333  50.353  -43.739 1.00 5.79   ? 466 ASN A1 N   1 
ATOM 3378 C CA  . ASN A 1 466 ? 83.137  51.766  -43.455 1.00 5.82   ? 466 ASN A1 CA  1 
ATOM 3379 C C   . ASN A 1 466 ? 81.767  52.299  -43.826 1.00 5.96   ? 466 ASN A1 C   1 
ATOM 3380 O O   . ASN A 1 466 ? 81.408  53.384  -43.365 1.00 7.77   ? 466 ASN A1 O   1 
ATOM 3381 C CB  . ASN A 1 466 ? 84.184  52.597  -44.184 1.00 5.92   ? 466 ASN A1 CB  1 
ATOM 3382 C CG  . ASN A 1 466 ? 85.573  52.151  -43.881 1.00 6.06   ? 466 ASN A1 CG  1 
ATOM 3383 O OD1 . ASN A 1 466 ? 86.117  52.459  -42.828 1.00 6.06   ? 466 ASN A1 OD1 1 
ATOM 3384 N ND2 . ASN A 1 466 ? 86.162  51.413  -44.801 1.00 7.23   ? 466 ASN A1 ND2 1 
ATOM 3385 N N   . GLY A 1 467 ? 81.008  51.596  -44.652 1.00 3.95   ? 467 GLY A1 N   1 
ATOM 3386 C CA  . GLY A 1 467 ? 79.738  52.129  -45.093 1.00 4.18   ? 467 GLY A1 CA  1 
ATOM 3387 C C   . GLY A 1 467 ? 78.700  52.100  -43.991 1.00 4.82   ? 467 GLY A1 C   1 
ATOM 3388 O O   . GLY A 1 467 ? 78.821  51.372  -43.011 1.00 5.04   ? 467 GLY A1 O   1 
ATOM 3389 N N   . GLN A 1 468 ? 77.676  52.927  -44.150 1.00 4.51   ? 468 GLN A1 N   1 
ATOM 3390 C CA  . GLN A 1 468 ? 76.561  52.922  -43.223 1.00 4.77   ? 468 GLN A1 CA  1 
ATOM 3391 C C   . GLN A 1 468 ? 75.771  51.634  -43.352 1.00 6.01   ? 468 GLN A1 C   1 
ATOM 3392 O O   . GLN A 1 468 ? 75.795  50.958  -44.379 1.00 6.12   ? 468 GLN A1 O   1 
ATOM 3393 C CB  . GLN A 1 468 ? 75.628  54.092  -43.490 1.00 3.65   ? 468 GLN A1 CB  1 
ATOM 3394 C CG  . GLN A 1 468 ? 76.176  55.421  -43.108 1.00 3.24   ? 468 GLN A1 CG  1 
ATOM 3395 C CD  . GLN A 1 468 ? 75.090  56.437  -42.942 1.00 4.62   ? 468 GLN A1 CD  1 
ATOM 3396 O OE1 . GLN A 1 468 ? 74.038  56.150  -42.383 1.00 6.55   ? 468 GLN A1 OE1 1 
ATOM 3397 N NE2 . GLN A 1 468 ? 75.331  57.637  -43.434 1.00 2.51   ? 468 GLN A1 NE2 1 
ATOM 3398 N N   . ILE A 1 469 ? 75.049  51.305  -42.295 1.00 4.98   ? 469 ILE A1 N   1 
ATOM 3399 C CA  . ILE A 1 469 ? 74.174  50.150  -42.336 1.00 3.70   ? 469 ILE A1 CA  1 
ATOM 3400 C C   . ILE A 1 469 ? 72.774  50.628  -42.673 1.00 5.23   ? 469 ILE A1 C   1 
ATOM 3401 O O   . ILE A 1 469 ? 72.148  50.129  -43.609 1.00 4.63   ? 469 ILE A1 O   1 
ATOM 3402 C CB  . ILE A 1 469 ? 74.205  49.382  -41.009 1.00 2.46   ? 469 ILE A1 CB  1 
ATOM 3403 C CG1 . ILE A 1 469 ? 75.622  48.937  -40.701 1.00 2.34   ? 469 ILE A1 CG1 1 
ATOM 3404 C CG2 . ILE A 1 469 ? 73.276  48.200  -41.070 1.00 2.24   ? 469 ILE A1 CG2 1 
ATOM 3405 C CD1 . ILE A 1 469 ? 75.717  48.152  -39.464 1.00 2.06   ? 469 ILE A1 CD1 1 
ATOM 3406 N N   . TRP A 1 470 ? 72.272  51.597  -41.921 1.00 5.61   ? 470 TRP A1 N   1 
ATOM 3407 C CA  . TRP A 1 470 ? 70.929  52.117  -42.113 1.00 5.04   ? 470 TRP A1 CA  1 
ATOM 3408 C C   . TRP A 1 470 ? 70.962  53.634  -42.187 1.00 6.36   ? 470 TRP A1 C   1 
ATOM 3409 O O   . TRP A 1 470 ? 71.749  54.287  -41.503 1.00 5.20   ? 470 TRP A1 O   1 
ATOM 3410 C CB  . TRP A 1 470 ? 69.982  51.657  -40.987 1.00 3.41   ? 470 TRP A1 CB  1 
ATOM 3411 C CG  . TRP A 1 470 ? 70.306  52.169  -39.605 1.00 2.44   ? 470 TRP A1 CG  1 
ATOM 3412 C CD1 . TRP A 1 470 ? 69.928  53.359  -39.063 1.00 2.20   ? 470 TRP A1 CD1 1 
ATOM 3413 C CD2 . TRP A 1 470 ? 71.034  51.481  -38.580 1.00 2.33   ? 470 TRP A1 CD2 1 
ATOM 3414 N NE1 . TRP A 1 470 ? 70.396  53.468  -37.783 1.00 2.00   ? 470 TRP A1 NE1 1 
ATOM 3415 C CE2 . TRP A 1 470 ? 71.076  52.325  -37.463 1.00 2.00   ? 470 TRP A1 CE2 1 
ATOM 3416 C CE3 . TRP A 1 470 ? 71.662  50.238  -38.504 1.00 2.06   ? 470 TRP A1 CE3 1 
ATOM 3417 C CZ2 . TRP A 1 470 ? 71.719  51.968  -36.286 1.00 2.00   ? 470 TRP A1 CZ2 1 
ATOM 3418 C CZ3 . TRP A 1 470 ? 72.301  49.890  -37.342 1.00 2.02   ? 470 TRP A1 CZ3 1 
ATOM 3419 C CH2 . TRP A 1 470 ? 72.325  50.746  -36.248 1.00 2.00   ? 470 TRP A1 CH2 1 
ATOM 3420 N N   . ASP A 1 471 ? 70.099  54.189  -43.028 1.00 7.09   ? 471 ASP A1 N   1 
ATOM 3421 C CA  . ASP A 1 471 ? 69.892  55.624  -43.110 1.00 7.54   ? 471 ASP A1 CA  1 
ATOM 3422 C C   . ASP A 1 471 ? 68.435  55.926  -42.815 1.00 7.91   ? 471 ASP A1 C   1 
ATOM 3423 O O   . ASP A 1 471 ? 67.612  55.029  -42.635 1.00 7.06   ? 471 ASP A1 O   1 
ATOM 3424 C CB  . ASP A 1 471 ? 70.275  56.186  -44.480 1.00 6.61   ? 471 ASP A1 CB  1 
ATOM 3425 C CG  . ASP A 1 471 ? 70.840  57.590  -44.398 1.00 5.54   ? 471 ASP A1 CG  1 
ATOM 3426 O OD1 . ASP A 1 471 ? 70.691  58.229  -43.342 1.00 2.14   ? 471 ASP A1 OD1 1 
ATOM 3427 O OD2 . ASP A 1 471 ? 71.434  58.057  -45.386 1.00 7.33   ? 471 ASP A1 OD2 1 
ATOM 3428 N N   . LYS A 1 472 ? 68.127  57.208  -42.759 1.00 8.68   ? 472 LYS A1 N   1 
ATOM 3429 C CA  . LYS A 1 472 ? 66.794  57.695  -42.468 1.00 8.80   ? 472 LYS A1 CA  1 
ATOM 3430 C C   . LYS A 1 472 ? 66.195  58.306  -43.720 1.00 9.75   ? 472 LYS A1 C   1 
ATOM 3431 O O   . LYS A 1 472 ? 66.853  59.085  -44.412 1.00 11.39  ? 472 LYS A1 O   1 
ATOM 3432 C CB  . LYS A 1 472 ? 66.861  58.734  -41.353 1.00 10.04  ? 472 LYS A1 CB  1 
ATOM 3433 C CG  . LYS A 1 472 ? 65.549  59.130  -40.758 1.00 15.70  ? 472 LYS A1 CG  1 
ATOM 3434 C CD  . LYS A 1 472 ? 65.753  60.363  -39.936 1.00 20.67  ? 472 LYS A1 CD  1 
ATOM 3435 C CE  . LYS A 1 472 ? 64.493  60.783  -39.235 1.00 25.20  ? 472 LYS A1 CE  1 
ATOM 3436 N NZ  . LYS A 1 472 ? 64.710  62.057  -38.500 1.00 26.12  ? 472 LYS A1 NZ  1 
ATOM 3437 N N   . GLU A 1 473 ? 64.955  57.943  -44.017 1.00 10.64  ? 473 GLU A1 N   1 
ATOM 3438 C CA  . GLU A 1 473 ? 64.282  58.489  -45.183 1.00 11.33  ? 473 GLU A1 CA  1 
ATOM 3439 C C   . GLU A 1 473 ? 63.917  59.947  -44.942 1.00 11.53  ? 473 GLU A1 C   1 
ATOM 3440 O O   . GLU A 1 473 ? 63.629  60.354  -43.814 1.00 13.74  ? 473 GLU A1 O   1 
ATOM 3441 C CB  . GLU A 1 473 ? 63.037  57.668  -45.514 1.00 11.78  ? 473 GLU A1 CB  1 
ATOM 3442 C CG  . GLU A 1 473 ? 62.427  57.919  -46.888 1.00 12.76  ? 473 GLU A1 CG  1 
ATOM 3443 C CD  . GLU A 1 473 ? 63.441  57.932  -48.022 1.00 14.70  ? 473 GLU A1 CD  1 
ATOM 3444 O OE1 . GLU A 1 473 ? 63.906  59.027  -48.396 1.00 16.92  ? 473 GLU A1 OE1 1 
ATOM 3445 O OE2 . GLU A 1 473 ? 63.758  56.854  -48.561 1.00 16.63  ? 473 GLU A1 OE2 1 
ATOM 3446 N N   . PHE A 1 474 ? 63.964  60.737  -46.014 1.00 9.53   ? 474 PHE A1 N   1 
ATOM 3447 C CA  . PHE A 1 474 ? 63.744  62.173  -45.920 1.00 7.28   ? 474 PHE A1 CA  1 
ATOM 3448 C C   . PHE A 1 474 ? 62.306  62.478  -45.529 1.00 7.81   ? 474 PHE A1 C   1 
ATOM 3449 O O   . PHE A 1 474 ? 61.380  61.749  -45.888 1.00 8.69   ? 474 PHE A1 O   1 
ATOM 3450 C CB  . PHE A 1 474 ? 64.052  62.853  -47.250 1.00 6.50   ? 474 PHE A1 CB  1 
ATOM 3451 C CG  . PHE A 1 474 ? 65.515  63.008  -47.542 1.00 6.67   ? 474 PHE A1 CG  1 
ATOM 3452 C CD1 . PHE A 1 474 ? 66.473  62.694  -46.601 1.00 7.37   ? 474 PHE A1 CD1 1 
ATOM 3453 C CD2 . PHE A 1 474 ? 65.925  63.484  -48.769 1.00 6.14   ? 474 PHE A1 CD2 1 
ATOM 3454 C CE1 . PHE A 1 474 ? 67.806  62.841  -46.887 1.00 7.08   ? 474 PHE A1 CE1 1 
ATOM 3455 C CE2 . PHE A 1 474 ? 67.256  63.635  -49.050 1.00 6.57   ? 474 PHE A1 CE2 1 
ATOM 3456 C CZ  . PHE A 1 474 ? 68.195  63.311  -48.108 1.00 6.49   ? 474 PHE A1 CZ  1 
ATOM 3457 N N   . ASP A 1 475 ? 62.121  63.567  -44.797 1.00 7.99   ? 475 ASP A1 N   1 
ATOM 3458 C CA  . ASP A 1 475 ? 60.787  64.015  -44.409 1.00 8.24   ? 475 ASP A1 CA  1 
ATOM 3459 C C   . ASP A 1 475 ? 60.237  65.004  -45.430 1.00 9.00   ? 475 ASP A1 C   1 
ATOM 3460 O O   . ASP A 1 475 ? 59.753  66.080  -45.100 1.00 11.78  ? 475 ASP A1 O   1 
ATOM 3461 C CB  . ASP A 1 475 ? 60.822  64.625  -43.016 1.00 8.92   ? 475 ASP A1 CB  1 
ATOM 3462 C CG  . ASP A 1 475 ? 59.476  64.598  -42.338 1.00 10.26  ? 475 ASP A1 CG  1 
ATOM 3463 O OD1 . ASP A 1 475 ? 58.619  63.796  -42.759 1.00 11.91  ? 475 ASP A1 OD1 1 
ATOM 3464 O OD2 . ASP A 1 475 ? 59.272  65.379  -41.387 1.00 10.82  ? 475 ASP A1 OD2 1 
ATOM 3465 N N   . THR A 1 476 ? 60.305  64.612  -46.690 1.00 9.07   ? 476 THR A1 N   1 
ATOM 3466 C CA  . THR A 1 476 ? 59.690  65.338  -47.785 1.00 9.13   ? 476 THR A1 CA  1 
ATOM 3467 C C   . THR A 1 476 ? 58.483  64.553  -48.270 1.00 10.08  ? 476 THR A1 C   1 
ATOM 3468 O O   . THR A 1 476 ? 58.159  63.480  -47.759 1.00 10.71  ? 476 THR A1 O   1 
ATOM 3469 C CB  . THR A 1 476 ? 60.685  65.572  -48.920 1.00 8.64   ? 476 THR A1 CB  1 
ATOM 3470 O OG1 . THR A 1 476 ? 61.370  64.351  -49.217 1.00 7.76   ? 476 THR A1 OG1 1 
ATOM 3471 C CG2 . THR A 1 476 ? 61.697  66.631  -48.532 1.00 8.20   ? 476 THR A1 CG2 1 
ATOM 3472 N N   . ASP A 1 477 ? 57.818  65.096  -49.275 1.00 9.72   ? 477 ASP A1 N   1 
ATOM 3473 C CA  . ASP A 1 477 ? 56.606  64.473  -49.778 1.00 8.73   ? 477 ASP A1 CA  1 
ATOM 3474 C C   . ASP A 1 477 ? 56.877  63.516  -50.926 1.00 8.83   ? 477 ASP A1 C   1 
ATOM 3475 O O   . ASP A 1 477 ? 56.174  62.510  -51.059 1.00 10.04  ? 477 ASP A1 O   1 
ATOM 3476 C CB  . ASP A 1 477 ? 55.626  65.561  -50.207 1.00 11.99  ? 477 ASP A1 CB  1 
ATOM 3477 C CG  . ASP A 1 477 ? 55.195  66.428  -49.042 1.00 16.69  ? 477 ASP A1 CG  1 
ATOM 3478 O OD1 . ASP A 1 477 ? 55.167  65.915  -47.907 1.00 19.56  ? 477 ASP A1 OD1 1 
ATOM 3479 O OD2 . ASP A 1 477 ? 54.902  67.621  -49.251 1.00 18.26  ? 477 ASP A1 OD2 1 
ATOM 3480 N N   . LEU A 1 478 ? 57.884  63.797  -51.747 1.00 9.10   ? 478 LEU A1 N   1 
ATOM 3481 C CA  . LEU A 1 478 ? 58.280  62.934  -52.855 1.00 7.50   ? 478 LEU A1 CA  1 
ATOM 3482 C C   . LEU A 1 478 ? 59.693  62.458  -52.556 1.00 6.56   ? 478 LEU A1 C   1 
ATOM 3483 O O   . LEU A 1 478 ? 60.670  63.143  -52.855 1.00 6.53   ? 478 LEU A1 O   1 
ATOM 3484 C CB  . LEU A 1 478 ? 58.193  63.666  -54.176 1.00 7.98   ? 478 LEU A1 CB  1 
ATOM 3485 C CG  . LEU A 1 478 ? 56.852  64.334  -54.470 1.00 8.99   ? 478 LEU A1 CG  1 
ATOM 3486 C CD1 . LEU A 1 478 ? 56.883  64.973  -55.833 1.00 10.63  ? 478 LEU A1 CD1 1 
ATOM 3487 C CD2 . LEU A 1 478 ? 55.730  63.331  -54.384 1.00 9.26   ? 478 LEU A1 CD2 1 
ATOM 3488 N N   . LYS A 1 479 ? 59.792  61.289  -51.964 1.00 6.00   ? 479 LYS A1 N   1 
ATOM 3489 C CA  . LYS A 1 479 ? 61.038  60.753  -51.450 1.00 4.36   ? 479 LYS A1 CA  1 
ATOM 3490 C C   . LYS A 1 479 ? 61.881  60.153  -52.573 1.00 4.21   ? 479 LYS A1 C   1 
ATOM 3491 O O   . LYS A 1 479 ? 61.340  59.682  -53.576 1.00 8.02   ? 479 LYS A1 O   1 
ATOM 3492 C CB  . LYS A 1 479 ? 60.742  59.696  -50.398 1.00 3.40   ? 479 LYS A1 CB  1 
ATOM 3493 C CG  . LYS A 1 479 ? 59.822  60.198  -49.325 1.00 4.49   ? 479 LYS A1 CG  1 
ATOM 3494 C CD  . LYS A 1 479 ? 59.298  59.084  -48.472 1.00 6.39   ? 479 LYS A1 CD  1 
ATOM 3495 C CE  . LYS A 1 479 ? 58.548  59.656  -47.299 1.00 10.07  ? 479 LYS A1 CE  1 
ATOM 3496 N NZ  . LYS A 1 479 ? 59.329  60.750  -46.675 1.00 13.95  ? 479 LYS A1 NZ  1 
ATOM 3497 N N   . PRO A 1 480 ? 63.207  60.173  -52.439 1.00 3.39   ? 480 PRO A1 N   1 
ATOM 3498 C CA  . PRO A 1 480 ? 64.051  59.548  -53.455 1.00 2.16   ? 480 PRO A1 CA  1 
ATOM 3499 C C   . PRO A 1 480 ? 63.942  58.037  -53.420 1.00 2.00   ? 480 PRO A1 C   1 
ATOM 3500 O O   . PRO A 1 480 ? 63.595  57.438  -52.403 1.00 3.42   ? 480 PRO A1 O   1 
ATOM 3501 C CB  . PRO A 1 480 ? 65.459  60.008  -53.072 1.00 2.00   ? 480 PRO A1 CB  1 
ATOM 3502 C CG  . PRO A 1 480 ? 65.373  60.303  -51.654 1.00 2.50   ? 480 PRO A1 CG  1 
ATOM 3503 C CD  . PRO A 1 480 ? 64.022  60.875  -51.437 1.00 2.85   ? 480 PRO A1 CD  1 
ATOM 3504 N N   . ARG A 1 481 ? 64.233  57.417  -54.559 1.00 2.00   ? 481 ARG A1 N   1 
ATOM 3505 C CA  . ARG A 1 481 ? 64.147  55.967  -54.638 1.00 2.00   ? 481 ARG A1 CA  1 
ATOM 3506 C C   . ARG A 1 481 ? 65.378  55.302  -54.048 1.00 2.56   ? 481 ARG A1 C   1 
ATOM 3507 O O   . ARG A 1 481 ? 65.328  54.128  -53.672 1.00 3.69   ? 481 ARG A1 O   1 
ATOM 3508 C CB  . ARG A 1 481 ? 63.951  55.540  -56.086 1.00 2.00   ? 481 ARG A1 CB  1 
ATOM 3509 C CG  . ARG A 1 481 ? 62.975  56.400  -56.842 1.00 3.68   ? 481 ARG A1 CG  1 
ATOM 3510 C CD  . ARG A 1 481 ? 63.134  56.197  -58.326 1.00 7.48   ? 481 ARG A1 CD  1 
ATOM 3511 N NE  . ARG A 1 481 ? 62.438  55.010  -58.798 1.00 11.30  ? 481 ARG A1 NE  1 
ATOM 3512 C CZ  . ARG A 1 481 ? 62.853  54.253  -59.806 1.00 14.30  ? 481 ARG A1 CZ  1 
ATOM 3513 N NH1 . ARG A 1 481 ? 63.973  54.552  -60.445 1.00 16.10  ? 481 ARG A1 NH1 1 
ATOM 3514 N NH2 . ARG A 1 481 ? 62.153  53.192  -60.167 1.00 16.52  ? 481 ARG A1 NH2 1 
ATOM 3515 N N   . LEU A 1 482 ? 66.482  56.032  -53.952 1.00 3.66   ? 482 LEU A1 N   1 
ATOM 3516 C CA  . LEU A 1 482 ? 67.733  55.501  -53.443 1.00 3.60   ? 482 LEU A1 CA  1 
ATOM 3517 C C   . LEU A 1 482 ? 68.303  56.430  -52.387 1.00 5.61   ? 482 LEU A1 C   1 
ATOM 3518 O O   . LEU A 1 482 ? 67.929  57.598  -52.290 1.00 8.42   ? 482 LEU A1 O   1 
ATOM 3519 C CB  . LEU A 1 482 ? 68.785  55.340  -54.538 1.00 2.58   ? 482 LEU A1 CB  1 
ATOM 3520 C CG  . LEU A 1 482 ? 68.825  54.159  -55.495 1.00 2.68   ? 482 LEU A1 CG  1 
ATOM 3521 C CD1 . LEU A 1 482 ? 67.766  54.281  -56.560 1.00 2.00   ? 482 LEU A1 CD1 1 
ATOM 3522 C CD2 . LEU A 1 482 ? 70.194  54.092  -56.117 1.00 2.94   ? 482 LEU A1 CD2 1 
ATOM 3523 N N   . HIS A 1 483 ? 69.213  55.887  -51.596 1.00 6.37   ? 483 HIS A1 N   1 
ATOM 3524 C CA  . HIS A 1 483 ? 70.164  56.668  -50.827 1.00 6.42   ? 483 HIS A1 CA  1 
ATOM 3525 C C   . HIS A 1 483 ? 71.540  56.185  -51.236 1.00 8.90   ? 483 HIS A1 C   1 
ATOM 3526 O O   . HIS A 1 483 ? 71.784  54.979  -51.271 1.00 11.63  ? 483 HIS A1 O   1 
ATOM 3527 C CB  . HIS A 1 483 ? 69.948  56.497  -49.328 1.00 5.55   ? 483 HIS A1 CB  1 
ATOM 3528 C CG  . HIS A 1 483 ? 68.936  57.438  -48.754 1.00 5.84   ? 483 HIS A1 CG  1 
ATOM 3529 N ND1 . HIS A 1 483 ? 67.634  57.486  -49.195 1.00 6.51   ? 483 HIS A1 ND1 1 
ATOM 3530 C CD2 . HIS A 1 483 ? 69.033  58.355  -47.768 1.00 4.64   ? 483 HIS A1 CD2 1 
ATOM 3531 C CE1 . HIS A 1 483 ? 66.974  58.403  -48.515 1.00 4.38   ? 483 HIS A1 CE1 1 
ATOM 3532 N NE2 . HIS A 1 483 ? 67.799  58.941  -47.640 1.00 5.19   ? 483 HIS A1 NE2 1 
ATOM 3533 N N   . VAL A 1 484 ? 72.430  57.116  -51.575 1.00 8.56   ? 484 VAL A1 N   1 
ATOM 3534 C CA  . VAL A 1 484 ? 73.739  56.733  -52.089 1.00 6.61   ? 484 VAL A1 CA  1 
ATOM 3535 C C   . VAL A 1 484 ? 74.670  56.208  -51.011 1.00 6.46   ? 484 VAL A1 C   1 
ATOM 3536 O O   . VAL A 1 484 ? 75.690  55.588  -51.341 1.00 6.82   ? 484 VAL A1 O   1 
ATOM 3537 C CB  . VAL A 1 484 ? 74.420  57.909  -52.813 1.00 4.97   ? 484 VAL A1 CB  1 
ATOM 3538 C CG1 . VAL A 1 484 ? 73.632  58.290  -54.040 1.00 4.22   ? 484 VAL A1 CG1 1 
ATOM 3539 C CG2 . VAL A 1 484 ? 74.551  59.096  -51.890 1.00 5.77   ? 484 VAL A1 CG2 1 
ATOM 3540 N N   . ASN A 1 485 ? 74.351  56.415  -49.740 1.00 5.19   ? 485 ASN A1 N   1 
ATOM 3541 C CA  . ASN A 1 485 ? 75.265  56.101  -48.658 1.00 4.94   ? 485 ASN A1 CA  1 
ATOM 3542 C C   . ASN A 1 485 ? 74.924  54.835  -47.894 1.00 6.54   ? 485 ASN A1 C   1 
ATOM 3543 O O   . ASN A 1 485 ? 75.832  54.212  -47.347 1.00 8.91   ? 485 ASN A1 O   1 
ATOM 3544 C CB  . ASN A 1 485 ? 75.329  57.266  -47.668 1.00 2.76   ? 485 ASN A1 CB  1 
ATOM 3545 C CG  . ASN A 1 485 ? 73.976  57.655  -47.160 1.00 2.18   ? 485 ASN A1 CG  1 
ATOM 3546 O OD1 . ASN A 1 485 ? 72.966  57.294  -47.746 1.00 2.00   ? 485 ASN A1 OD1 1 
ATOM 3547 N ND2 . ASN A 1 485 ? 73.940  58.388  -46.060 1.00 2.00   ? 485 ASN A1 ND2 1 
ATOM 3548 N N   . ALA A 1 486 ? 73.656  54.434  -47.837 1.00 6.54   ? 486 ALA A1 N   1 
ATOM 3549 C CA  . ALA A 1 486 ? 73.305  53.256  -47.071 1.00 5.77   ? 486 ALA A1 CA  1 
ATOM 3550 C C   . ALA A 1 486 ? 72.480  52.283  -47.897 1.00 5.92   ? 486 ALA A1 C   1 
ATOM 3551 O O   . ALA A 1 486 ? 71.710  52.705  -48.762 1.00 6.98   ? 486 ALA A1 O   1 
ATOM 3552 C CB  . ALA A 1 486 ? 72.518  53.633  -45.827 1.00 5.44   ? 486 ALA A1 CB  1 
ATOM 3553 N N   . PRO A 1 487 ? 72.615  50.978  -47.653 1.00 4.00   ? 487 PRO A1 N   1 
ATOM 3554 C CA  . PRO A 1 487 ? 71.760  50.022  -48.361 1.00 2.69   ? 487 PRO A1 CA  1 
ATOM 3555 C C   . PRO A 1 487 ? 70.364  49.915  -47.783 1.00 3.45   ? 487 PRO A1 C   1 
ATOM 3556 O O   . PRO A 1 487 ? 69.415  49.675  -48.539 1.00 6.73   ? 487 PRO A1 O   1 
ATOM 3557 C CB  . PRO A 1 487 ? 72.531  48.712  -48.217 1.00 2.01   ? 487 PRO A1 CB  1 
ATOM 3558 C CG  . PRO A 1 487 ? 73.292  48.873  -46.977 1.00 3.14   ? 487 PRO A1 CG  1 
ATOM 3559 C CD  . PRO A 1 487 ? 73.700  50.300  -46.929 1.00 3.46   ? 487 PRO A1 CD  1 
ATOM 3560 N N   . PHE A 1 488 ? 70.205  50.068  -46.475 1.00 3.36   ? 488 PHE A1 N   1 
ATOM 3561 C CA  . PHE A 1 488 ? 68.909  50.033  -45.824 1.00 4.80   ? 488 PHE A1 CA  1 
ATOM 3562 C C   . PHE A 1 488 ? 68.485  51.449  -45.488 1.00 5.28   ? 488 PHE A1 C   1 
ATOM 3563 O O   . PHE A 1 488 ? 69.279  52.229  -44.965 1.00 9.00   ? 488 PHE A1 O   1 
ATOM 3564 C CB  . PHE A 1 488 ? 68.953  49.205  -44.542 1.00 4.81   ? 488 PHE A1 CB  1 
ATOM 3565 C CG  . PHE A 1 488 ? 69.407  47.795  -44.744 1.00 5.57   ? 488 PHE A1 CG  1 
ATOM 3566 C CD1 . PHE A 1 488 ? 68.557  46.856  -45.281 1.00 5.78   ? 488 PHE A1 CD1 1 
ATOM 3567 C CD2 . PHE A 1 488 ? 70.680  47.405  -44.380 1.00 6.77   ? 488 PHE A1 CD2 1 
ATOM 3568 C CE1 . PHE A 1 488 ? 68.970  45.571  -45.461 1.00 5.33   ? 488 PHE A1 CE1 1 
ATOM 3569 C CE2 . PHE A 1 488 ? 71.093  46.114  -44.559 1.00 7.11   ? 488 PHE A1 CE2 1 
ATOM 3570 C CZ  . PHE A 1 488 ? 70.241  45.202  -45.103 1.00 6.16   ? 488 PHE A1 CZ  1 
ATOM 3571 N N   . VAL A 1 489 ? 67.240  51.785  -45.787 1.00 4.78   ? 489 VAL A1 N   1 
ATOM 3572 C CA  . VAL A 1 489 ? 66.683  53.086  -45.445 1.00 5.81   ? 489 VAL A1 CA  1 
ATOM 3573 C C   . VAL A 1 489 ? 65.409  52.874  -44.646 1.00 7.23   ? 489 VAL A1 C   1 
ATOM 3574 O O   . VAL A 1 489 ? 64.450  52.268  -45.135 1.00 7.62   ? 489 VAL A1 O   1 
ATOM 3575 C CB  . VAL A 1 489 ? 66.404  53.933  -46.697 1.00 4.42   ? 489 VAL A1 CB  1 
ATOM 3576 C CG1 . VAL A 1 489 ? 65.652  55.164  -46.320 1.00 3.94   ? 489 VAL A1 CG1 1 
ATOM 3577 C CG2 . VAL A 1 489 ? 67.698  54.307  -47.360 1.00 4.46   ? 489 VAL A1 CG2 1 
ATOM 3578 N N   . CYS A 1 490 ? 65.403  53.371  -43.416 1.00 10.64  ? 490 CYS A1 N   1 
ATOM 3579 C CA  . CYS A 1 490 ? 64.282  53.218  -42.503 1.00 16.08  ? 490 CYS A1 CA  1 
ATOM 3580 C C   . CYS A 1 490 ? 63.214  54.243  -42.852 1.00 18.29  ? 490 CYS A1 C   1 
ATOM 3581 O O   . CYS A 1 490 ? 63.415  55.443  -42.645 1.00 16.34  ? 490 CYS A1 O   1 
ATOM 3582 C CB  . CYS A 1 490 ? 64.749  53.396  -41.064 1.00 18.40  ? 490 CYS A1 CB  1 
ATOM 3583 S SG  . CYS A 1 490 ? 66.217  52.450  -40.688 1.00 22.46  ? 490 CYS A1 SG  1 
ATOM 3584 N N   . GLN A 1 491 ? 62.075  53.769  -43.354 1.00 24.05  ? 491 GLN A1 N   1 
ATOM 3585 C CA  . GLN A 1 491 ? 61.055  54.669  -43.878 1.00 30.54  ? 491 GLN A1 CA  1 
ATOM 3586 C C   . GLN A 1 491 ? 60.318  55.409  -42.768 1.00 33.08  ? 491 GLN A1 C   1 
ATOM 3587 O O   . GLN A 1 491 ? 60.357  56.641  -42.696 1.00 32.41  ? 491 GLN A1 O   1 
ATOM 3588 C CB  . GLN A 1 491 ? 60.062  53.896  -44.745 1.00 32.95  ? 491 GLN A1 CB  1 
ATOM 3589 C CG  . GLN A 1 491 ? 60.561  53.600  -46.147 1.00 37.07  ? 491 GLN A1 CG  1 
ATOM 3590 C CD  . GLN A 1 491 ? 61.170  52.221  -46.263 1.00 39.78  ? 491 GLN A1 CD  1 
ATOM 3591 O OE1 . GLN A 1 491 ? 60.915  51.350  -45.436 1.00 42.33  ? 491 GLN A1 OE1 1 
ATOM 3592 N NE2 . GLN A 1 491 ? 61.976  52.014  -47.296 1.00 40.28  ? 491 GLN A1 NE2 1 
ATOM 3593 N N   . ASN A 1 492 ? 59.636  54.672  -41.896 1.00 37.65  ? 492 ASN A1 N   1 
ATOM 3594 C CA  . ASN A 1 492 ? 58.768  55.312  -40.913 1.00 42.19  ? 492 ASN A1 CA  1 
ATOM 3595 C C   . ASN A 1 492 ? 59.571  55.952  -39.785 1.00 42.97  ? 492 ASN A1 C   1 
ATOM 3596 O O   . ASN A 1 492 ? 59.427  57.148  -39.514 1.00 46.35  ? 492 ASN A1 O   1 
ATOM 3597 C CB  . ASN A 1 492 ? 57.743  54.301  -40.397 1.00 45.42  ? 492 ASN A1 CB  1 
ATOM 3598 C CG  . ASN A 1 492 ? 58.372  52.987  -40.001 1.00 48.97  ? 492 ASN A1 CG  1 
ATOM 3599 O OD1 . ASN A 1 492 ? 59.592  52.849  -40.007 1.00 49.97  ? 492 ASN A1 OD1 1 
ATOM 3600 N ND2 . ASN A 1 492 ? 57.541  52.004  -39.677 1.00 50.15  ? 492 ASN A1 ND2 1 
ATOM 3601 N N   . ASN A 1 493 ? 60.436  55.186  -39.126 1.00 42.78  ? 493 ASN A1 N   1 
ATOM 3602 C CA  . ASN A 1 493 ? 61.276  55.772  -38.092 1.00 41.27  ? 493 ASN A1 CA  1 
ATOM 3603 C C   . ASN A 1 493 ? 62.601  55.031  -38.026 1.00 36.08  ? 493 ASN A1 C   1 
ATOM 3604 O O   . ASN A 1 493 ? 62.699  53.861  -38.399 1.00 34.44  ? 493 ASN A1 O   1 
ATOM 3605 C CB  . ASN A 1 493 ? 60.586  55.768  -36.725 1.00 46.91  ? 493 ASN A1 CB  1 
ATOM 3606 C CG  . ASN A 1 493 ? 60.026  54.422  -36.361 1.00 50.44  ? 493 ASN A1 CG  1 
ATOM 3607 O OD1 . ASN A 1 493 ? 59.850  53.560  -37.216 1.00 52.94  ? 493 ASN A1 OD1 1 
ATOM 3608 N ND2 . ASN A 1 493 ? 59.737  54.230  -35.079 1.00 51.76  ? 493 ASN A1 ND2 1 
ATOM 3609 N N   . CYS A 1 494 ? 63.615  55.743  -37.564 1.00 27.95  ? 494 CYS A1 N   1 
ATOM 3610 C CA  . CYS A 1 494 ? 64.990  55.300  -37.445 1.00 21.96  ? 494 CYS A1 CA  1 
ATOM 3611 C C   . CYS A 1 494 ? 65.285  54.995  -35.982 1.00 15.47  ? 494 CYS A1 C   1 
ATOM 3612 O O   . CYS A 1 494 ? 64.509  55.383  -35.103 1.00 17.41  ? 494 CYS A1 O   1 
ATOM 3613 C CB  . CYS A 1 494 ? 65.922  56.404  -37.967 1.00 22.46  ? 494 CYS A1 CB  1 
ATOM 3614 S SG  . CYS A 1 494 ? 67.439  55.882  -38.776 1.00 25.70  ? 494 CYS A1 SG  1 
ATOM 3615 N N   . PRO A 1 495 ? 66.352  54.248  -35.680 1.00 9.04   ? 495 PRO A1 N   1 
ATOM 3616 C CA  . PRO A 1 495 ? 66.769  54.108  -34.284 1.00 7.04   ? 495 PRO A1 CA  1 
ATOM 3617 C C   . PRO A 1 495 ? 67.156  55.439  -33.670 1.00 7.64   ? 495 PRO A1 C   1 
ATOM 3618 O O   . PRO A 1 495 ? 67.660  56.339  -34.343 1.00 7.14   ? 495 PRO A1 O   1 
ATOM 3619 C CB  . PRO A 1 495 ? 67.975  53.176  -34.368 1.00 5.14   ? 495 PRO A1 CB  1 
ATOM 3620 C CG  . PRO A 1 495 ? 67.720  52.370  -35.512 1.00 4.70   ? 495 PRO A1 CG  1 
ATOM 3621 C CD  . PRO A 1 495 ? 66.950  53.189  -36.504 1.00 7.43   ? 495 PRO A1 CD  1 
ATOM 3622 N N   . GLY A 1 496 ? 66.905  55.556  -32.372 1.00 7.85   ? 496 GLY A1 N   1 
ATOM 3623 C CA  . GLY A 1 496 ? 67.222  56.784  -31.682 1.00 8.55   ? 496 GLY A1 CA  1 
ATOM 3624 C C   . GLY A 1 496 ? 68.713  56.921  -31.451 1.00 9.89   ? 496 GLY A1 C   1 
ATOM 3625 O O   . GLY A 1 496 ? 69.409  55.954  -31.141 1.00 10.70  ? 496 GLY A1 O   1 
ATOM 3626 N N   . GLN A 1 497 ? 69.206  58.140  -31.618 1.00 10.02  ? 497 GLN A1 N   1 
ATOM 3627 C CA  . GLN A 1 497 ? 70.599  58.445  -31.358 1.00 9.18   ? 497 GLN A1 CA  1 
ATOM 3628 C C   . GLN A 1 497 ? 70.839  58.514  -29.860 1.00 8.97   ? 497 GLN A1 C   1 
ATOM 3629 O O   . GLN A 1 497 ? 69.990  58.990  -29.108 1.00 9.46   ? 497 GLN A1 O   1 
ATOM 3630 C CB  . GLN A 1 497 ? 70.989  59.765  -32.013 1.00 8.87   ? 497 GLN A1 CB  1 
ATOM 3631 C CG  . GLN A 1 497 ? 70.366  59.985  -33.364 1.00 8.88   ? 497 GLN A1 CG  1 
ATOM 3632 C CD  . GLN A 1 497 ? 71.037  61.100  -34.116 1.00 9.57   ? 497 GLN A1 CD  1 
ATOM 3633 O OE1 . GLN A 1 497 ? 71.797  60.859  -35.049 1.00 8.05   ? 497 GLN A1 OE1 1 
ATOM 3634 N NE2 . GLN A 1 497 ? 70.768  62.330  -33.716 1.00 8.90   ? 497 GLN A1 NE2 1 
ATOM 3635 N N   . LEU A 1 498 ? 72.001  58.040  -29.434 1.00 8.50   ? 498 LEU A1 N   1 
ATOM 3636 C CA  . LEU A 1 498 ? 72.343  57.941  -28.025 1.00 8.19   ? 498 LEU A1 CA  1 
ATOM 3637 C C   . LEU A 1 498 ? 73.377  59.001  -27.686 1.00 7.78   ? 498 LEU A1 C   1 
ATOM 3638 O O   . LEU A 1 498 ? 74.517  58.929  -28.152 1.00 8.61   ? 498 LEU A1 O   1 
ATOM 3639 C CB  . LEU A 1 498 ? 72.878  56.551  -27.700 1.00 8.85   ? 498 LEU A1 CB  1 
ATOM 3640 C CG  . LEU A 1 498 ? 73.193  56.277  -26.239 1.00 9.25   ? 498 LEU A1 CG  1 
ATOM 3641 C CD1 . LEU A 1 498 ? 71.921  55.970  -25.510 1.00 11.35  ? 498 LEU A1 CD1 1 
ATOM 3642 C CD2 . LEU A 1 498 ? 74.156  55.131  -26.142 1.00 8.70   ? 498 LEU A1 CD2 1 
ATOM 3643 N N   . PHE A 1 499 ? 72.985  59.965  -26.864 1.00 5.88   ? 499 PHE A1 N   1 
ATOM 3644 C CA  . PHE A 1 499 ? 73.857  61.050  -26.453 1.00 4.65   ? 499 PHE A1 CA  1 
ATOM 3645 C C   . PHE A 1 499 ? 74.352  60.831  -25.034 1.00 5.97   ? 499 PHE A1 C   1 
ATOM 3646 O O   . PHE A 1 499 ? 73.581  60.464  -24.149 1.00 7.05   ? 499 PHE A1 O   1 
ATOM 3647 C CB  . PHE A 1 499 ? 73.138  62.392  -26.539 1.00 2.80   ? 499 PHE A1 CB  1 
ATOM 3648 C CG  . PHE A 1 499 ? 72.507  62.656  -27.862 1.00 2.06   ? 499 PHE A1 CG  1 
ATOM 3649 C CD1 . PHE A 1 499 ? 73.279  62.844  -28.979 1.00 2.00   ? 499 PHE A1 CD1 1 
ATOM 3650 C CD2 . PHE A 1 499 ? 71.136  62.723  -27.985 1.00 2.09   ? 499 PHE A1 CD2 1 
ATOM 3651 C CE1 . PHE A 1 499 ? 72.702  63.081  -30.196 1.00 2.00   ? 499 PHE A1 CE1 1 
ATOM 3652 C CE2 . PHE A 1 499 ? 70.554  62.964  -29.203 1.00 2.23   ? 499 PHE A1 CE2 1 
ATOM 3653 C CZ  . PHE A 1 499 ? 71.340  63.142  -30.307 1.00 2.10   ? 499 PHE A1 CZ  1 
ATOM 3654 N N   . VAL A 1 500 ? 75.643  61.056  -24.824 1.00 6.97   ? 500 VAL A1 N   1 
ATOM 3655 C CA  . VAL A 1 500 ? 76.264  60.929  -23.515 1.00 6.93   ? 500 VAL A1 CA  1 
ATOM 3656 C C   . VAL A 1 500 ? 76.968  62.232  -23.180 1.00 7.42   ? 500 VAL A1 C   1 
ATOM 3657 O O   . VAL A 1 500 ? 77.353  62.999  -24.066 1.00 10.34  ? 500 VAL A1 O   1 
ATOM 3658 C CB  . VAL A 1 500 ? 77.256  59.753  -23.441 1.00 5.79   ? 500 VAL A1 CB  1 
ATOM 3659 C CG1 . VAL A 1 500 ? 76.523  58.442  -23.515 1.00 6.71   ? 500 VAL A1 CG1 1 
ATOM 3660 C CG2 . VAL A 1 500 ? 78.252  59.846  -24.549 1.00 6.38   ? 500 VAL A1 CG2 1 
ATOM 3661 N N   . LYS A 1 501 ? 77.141  62.473  -21.888 1.00 6.40   ? 501 LYS A1 N   1 
ATOM 3662 C CA  . LYS A 1 501 ? 77.727  63.706  -21.394 1.00 5.20   ? 501 LYS A1 CA  1 
ATOM 3663 C C   . LYS A 1 501 ? 78.164  63.469  -19.960 1.00 7.05   ? 501 LYS A1 C   1 
ATOM 3664 O O   . LYS A 1 501 ? 77.547  62.676  -19.251 1.00 8.74   ? 501 LYS A1 O   1 
ATOM 3665 C CB  . LYS A 1 501 ? 76.721  64.853  -21.460 1.00 2.86   ? 501 LYS A1 CB  1 
ATOM 3666 C CG  . LYS A 1 501 ? 77.296  66.220  -21.281 1.00 2.00   ? 501 LYS A1 CG  1 
ATOM 3667 C CD  . LYS A 1 501 ? 76.201  67.215  -21.065 1.00 2.04   ? 501 LYS A1 CD  1 
ATOM 3668 C CE  . LYS A 1 501 ? 76.529  68.073  -19.884 1.00 3.13   ? 501 LYS A1 CE  1 
ATOM 3669 N NZ  . LYS A 1 501 ? 75.449  69.039  -19.576 1.00 4.00   ? 501 LYS A1 NZ  1 
ATOM 3670 N N   . VAL A 1 502 ? 79.230  64.137  -19.545 1.00 6.27   ? 502 VAL A1 N   1 
ATOM 3671 C CA  . VAL A 1 502 ? 79.667  64.084  -18.156 1.00 4.88   ? 502 VAL A1 CA  1 
ATOM 3672 C C   . VAL A 1 502 ? 79.028  65.247  -17.410 1.00 5.45   ? 502 VAL A1 C   1 
ATOM 3673 O O   . VAL A 1 502 ? 79.195  66.406  -17.799 1.00 3.91   ? 502 VAL A1 O   1 
ATOM 3674 C CB  . VAL A 1 502 ? 81.195  64.130  -18.055 1.00 5.17   ? 502 VAL A1 CB  1 
ATOM 3675 C CG1 . VAL A 1 502 ? 81.621  64.073  -16.615 1.00 6.28   ? 502 VAL A1 CG1 1 
ATOM 3676 C CG2 . VAL A 1 502 ? 81.794  62.983  -18.810 1.00 5.19   ? 502 VAL A1 CG2 1 
ATOM 3677 N N   . ALA A 1 503 ? 78.287  64.935  -16.346 1.00 5.29   ? 503 ALA A1 N   1 
ATOM 3678 C CA  . ALA A 1 503 ? 77.574  65.944  -15.577 1.00 6.51   ? 503 ALA A1 CA  1 
ATOM 3679 C C   . ALA A 1 503 ? 78.567  66.869  -14.874 1.00 7.38   ? 503 ALA A1 C   1 
ATOM 3680 O O   . ALA A 1 503 ? 79.631  66.418  -14.442 1.00 9.30   ? 503 ALA A1 O   1 
ATOM 3681 C CB  . ALA A 1 503 ? 76.659  65.273  -14.554 1.00 5.52   ? 503 ALA A1 CB  1 
ATOM 3682 N N   . PRO A 1 504 ? 78.260  68.166  -14.769 1.00 6.89   ? 504 PRO A1 N   1 
ATOM 3683 C CA  . PRO A 1 504 ? 79.268  69.140  -14.317 1.00 7.13   ? 504 PRO A1 CA  1 
ATOM 3684 C C   . PRO A 1 504 ? 79.608  68.981  -12.843 1.00 7.53   ? 504 PRO A1 C   1 
ATOM 3685 O O   . PRO A 1 504 ? 78.768  69.193  -11.967 1.00 10.54  ? 504 PRO A1 O   1 
ATOM 3686 C CB  . PRO A 1 504 ? 78.606  70.494  -14.596 1.00 5.46   ? 504 PRO A1 CB  1 
ATOM 3687 C CG  . PRO A 1 504 ? 77.493  70.211  -15.505 1.00 6.41   ? 504 PRO A1 CG  1 
ATOM 3688 C CD  . PRO A 1 504 ? 77.027  68.840  -15.199 1.00 6.35   ? 504 PRO A1 CD  1 
ATOM 3689 N N   . ASN A 1 505 ? 80.853  68.601  -12.584 1.00 6.44   ? 505 ASN A1 N   1 
ATOM 3690 C CA  . ASN A 1 505 ? 81.406  68.516  -11.241 1.00 4.91   ? 505 ASN A1 CA  1 
ATOM 3691 C C   . ASN A 1 505 ? 81.995  69.880  -10.916 1.00 6.88   ? 505 ASN A1 C   1 
ATOM 3692 O O   . ASN A 1 505 ? 83.101  70.201  -11.353 1.00 6.37   ? 505 ASN A1 O   1 
ATOM 3693 C CB  . ASN A 1 505 ? 82.472  67.427  -11.170 1.00 4.10   ? 505 ASN A1 CB  1 
ATOM 3694 C CG  . ASN A 1 505 ? 82.389  66.602  -9.911  1.00 5.23   ? 505 ASN A1 CG  1 
ATOM 3695 O OD1 . ASN A 1 505 ? 81.727  66.980  -8.948  1.00 5.48   ? 505 ASN A1 OD1 1 
ATOM 3696 N ND2 . ASN A 1 505 ? 83.079  65.474  -9.903  1.00 5.12   ? 505 ASN A1 ND2 1 
ATOM 3697 N N   . LEU A 1 506 ? 81.266  70.680  -10.150 1.00 7.56   ? 506 LEU A1 N   1 
ATOM 3698 C CA  . LEU A 1 506 ? 81.654  72.061  -9.917  1.00 8.49   ? 506 LEU A1 CA  1 
ATOM 3699 C C   . LEU A 1 506 ? 82.542  72.185  -8.691  1.00 9.55   ? 506 LEU A1 C   1 
ATOM 3700 O O   . LEU A 1 506 ? 82.493  71.363  -7.774  1.00 9.82   ? 506 LEU A1 O   1 
ATOM 3701 C CB  . LEU A 1 506 ? 80.423  72.945  -9.740  1.00 8.77   ? 506 LEU A1 CB  1 
ATOM 3702 C CG  . LEU A 1 506 ? 79.363  72.829  -10.824 1.00 8.68   ? 506 LEU A1 CG  1 
ATOM 3703 C CD1 . LEU A 1 506 ? 78.111  73.538  -10.389 1.00 9.74   ? 506 LEU A1 CD1 1 
ATOM 3704 C CD2 . LEU A 1 506 ? 79.887  73.412  -12.101 1.00 7.25   ? 506 LEU A1 CD2 1 
ATOM 3705 N N   . THR A 1 507 ? 83.367  73.225  -8.692  1.00 10.96  ? 507 THR A1 N   1 
ATOM 3706 C CA  . THR A 1 507 ? 84.167  73.588  -7.539  1.00 10.98  ? 507 THR A1 CA  1 
ATOM 3707 C C   . THR A 1 507 ? 83.337  74.469  -6.613  1.00 10.60  ? 507 THR A1 C   1 
ATOM 3708 O O   . THR A 1 507 ? 82.214  74.858  -6.933  1.00 8.97   ? 507 THR A1 O   1 
ATOM 3709 C CB  . THR A 1 507 ? 85.442  74.290  -7.982  1.00 10.62  ? 507 THR A1 CB  1 
ATOM 3710 O OG1 . THR A 1 507 ? 85.105  75.550  -8.570  1.00 11.96  ? 507 THR A1 OG1 1 
ATOM 3711 C CG2 . THR A 1 507 ? 86.161  73.459  -9.007  1.00 11.66  ? 507 THR A1 CG2 1 
ATOM 3712 N N   . ASN A 1 508 ? 83.890  74.791  -5.446  1.00 11.55  ? 508 ASN A1 N   1 
ATOM 3713 C CA  . ASN A 1 508 ? 83.124  75.527  -4.450  1.00 12.03  ? 508 ASN A1 CA  1 
ATOM 3714 C C   . ASN A 1 508 ? 83.017  77.007  -4.760  1.00 13.48  ? 508 ASN A1 C   1 
ATOM 3715 O O   . ASN A 1 508 ? 82.192  77.692  -4.151  1.00 13.37  ? 508 ASN A1 O   1 
ATOM 3716 C CB  . ASN A 1 508 ? 83.737  75.350  -3.066  1.00 10.91  ? 508 ASN A1 CB  1 
ATOM 3717 C CG  . ASN A 1 508 ? 85.148  75.845  -2.995  1.00 13.05  ? 508 ASN A1 CG  1 
ATOM 3718 O OD1 . ASN A 1 508 ? 86.021  75.363  -3.707  1.00 14.57  ? 508 ASN A1 OD1 1 
ATOM 3719 N ND2 . ASN A 1 508 ? 85.387  76.813  -2.125  1.00 13.68  ? 508 ASN A1 ND2 1 
ATOM 3720 N N   . GLU A 1 509 ? 83.829  77.519  -5.673  1.00 15.20  ? 509 GLU A1 N   1 
ATOM 3721 C CA  . GLU A 1 509 ? 83.780  78.926  -6.052  1.00 18.84  ? 509 GLU A1 CA  1 
ATOM 3722 C C   . GLU A 1 509 ? 83.076  79.010  -7.399  1.00 17.57  ? 509 GLU A1 C   1 
ATOM 3723 O O   . GLU A 1 509 ? 83.709  79.100  -8.448  1.00 20.24  ? 509 GLU A1 O   1 
ATOM 3724 C CB  . GLU A 1 509 ? 85.181  79.525  -6.104  1.00 25.13  ? 509 GLU A1 CB  1 
ATOM 3725 C CG  . GLU A 1 509 ? 85.897  79.586  -4.756  1.00 34.13  ? 509 GLU A1 CG  1 
ATOM 3726 C CD  . GLU A 1 509 ? 85.275  80.572  -3.776  1.00 40.00  ? 509 GLU A1 CD  1 
ATOM 3727 O OE1 . GLU A 1 509 ? 84.639  81.552  -4.219  1.00 43.84  ? 509 GLU A1 OE1 1 
ATOM 3728 O OE2 . GLU A 1 509 ? 85.426  80.366  -2.554  1.00 41.41  ? 509 GLU A1 OE2 1 
ATOM 3729 N N   . TYR A 1 510 ? 81.747  78.983  -7.362  1.00 15.81  ? 510 TYR A1 N   1 
ATOM 3730 C CA  . TYR A 1 510 ? 80.933  79.090  -8.563  1.00 13.72  ? 510 TYR A1 CA  1 
ATOM 3731 C C   . TYR A 1 510 ? 79.810  80.078  -8.308  1.00 14.57  ? 510 TYR A1 C   1 
ATOM 3732 O O   . TYR A 1 510 ? 79.195  80.054  -7.240  1.00 16.38  ? 510 TYR A1 O   1 
ATOM 3733 C CB  . TYR A 1 510 ? 80.358  77.727  -8.974  1.00 12.40  ? 510 TYR A1 CB  1 
ATOM 3734 C CG  . TYR A 1 510 ? 79.293  77.808  -10.047 1.00 11.47  ? 510 TYR A1 CG  1 
ATOM 3735 C CD1 . TYR A 1 510 ? 79.636  78.030  -11.371 1.00 11.28  ? 510 TYR A1 CD1 1 
ATOM 3736 C CD2 . TYR A 1 510 ? 77.945  77.672  -9.735  1.00 10.62  ? 510 TYR A1 CD2 1 
ATOM 3737 C CE1 . TYR A 1 510 ? 78.675  78.117  -12.345 1.00 10.57  ? 510 TYR A1 CE1 1 
ATOM 3738 C CE2 . TYR A 1 510 ? 76.981  77.759  -10.704 1.00 11.22  ? 510 TYR A1 CE2 1 
ATOM 3739 C CZ  . TYR A 1 510 ? 77.350  77.983  -12.006 1.00 11.43  ? 510 TYR A1 CZ  1 
ATOM 3740 O OH  . TYR A 1 510 ? 76.388  78.069  -12.980 1.00 10.61  ? 510 TYR A1 OH  1 
ATOM 3741 N N   . ASP A 1 511 ? 79.546  80.943  -9.286  1.00 15.71  ? 511 ASP A1 N   1 
ATOM 3742 C CA  . ASP A 1 511 ? 78.363  81.785  -9.276  1.00 16.40  ? 511 ASP A1 CA  1 
ATOM 3743 C C   . ASP A 1 511 ? 77.909  81.987  -10.714 1.00 16.02  ? 511 ASP A1 C   1 
ATOM 3744 O O   . ASP A 1 511 ? 78.743  82.211  -11.603 1.00 16.80  ? 511 ASP A1 O   1 
ATOM 3745 C CB  . ASP A 1 511 ? 78.599  83.143  -8.603  1.00 19.17  ? 511 ASP A1 CB  1 
ATOM 3746 C CG  . ASP A 1 511 ? 79.722  83.921  -9.237  1.00 23.18  ? 511 ASP A1 CG  1 
ATOM 3747 O OD1 . ASP A 1 511 ? 79.625  85.162  -9.287  1.00 25.43  ? 511 ASP A1 OD1 1 
ATOM 3748 O OD2 . ASP A 1 511 ? 80.698  83.289  -9.685  1.00 26.06  ? 511 ASP A1 OD2 1 
ATOM 3749 N N   . PRO A 1 512 ? 76.611  81.870  -10.986 1.00 14.53  ? 512 PRO A1 N   1 
ATOM 3750 C CA  . PRO A 1 512 ? 76.093  82.049  -12.346 1.00 13.91  ? 512 PRO A1 CA  1 
ATOM 3751 C C   . PRO A 1 512 ? 75.718  83.493  -12.660 1.00 15.43  ? 512 PRO A1 C   1 
ATOM 3752 O O   . PRO A 1 512 ? 74.679  83.771  -13.258 1.00 14.69  ? 512 PRO A1 O   1 
ATOM 3753 C CB  . PRO A 1 512 ? 74.869  81.131  -12.361 1.00 12.91  ? 512 PRO A1 CB  1 
ATOM 3754 C CG  . PRO A 1 512 ? 74.442  81.031  -10.927 1.00 14.01  ? 512 PRO A1 CG  1 
ATOM 3755 C CD  . PRO A 1 512 ? 75.536  81.544  -10.040 1.00 14.22  ? 512 PRO A1 CD  1 
ATOM 3756 N N   . ASP A 1 513 ? 76.582  84.425  -12.277 1.00 18.74  ? 513 ASP A1 N   1 
ATOM 3757 C CA  . ASP A 1 513 ? 76.391  85.830  -12.580 1.00 24.76  ? 513 ASP A1 CA  1 
ATOM 3758 C C   . ASP A 1 513 ? 77.652  86.454  -13.145 1.00 26.72  ? 513 ASP A1 C   1 
ATOM 3759 O O   . ASP A 1 513 ? 77.659  87.657  -13.426 1.00 26.66  ? 513 ASP A1 O   1 
ATOM 3760 C CB  . ASP A 1 513 ? 75.955  86.605  -11.331 1.00 29.44  ? 513 ASP A1 CB  1 
ATOM 3761 C CG  . ASP A 1 513 ? 74.689  86.055  -10.716 1.00 34.56  ? 513 ASP A1 CG  1 
ATOM 3762 O OD1 . ASP A 1 513 ? 73.693  85.899  -11.449 1.00 35.00  ? 513 ASP A1 OD1 1 
ATOM 3763 O OD2 . ASP A 1 513 ? 74.687  85.776  -9.500  1.00 34.70  ? 513 ASP A1 OD2 1 
ATOM 3764 N N   . ALA A 1 514 ? 78.713  85.678  -13.308 1.00 28.77  ? 514 ALA A1 N   1 
ATOM 3765 C CA  . ALA A 1 514 ? 79.943  86.145  -13.915 1.00 32.08  ? 514 ALA A1 CA  1 
ATOM 3766 C C   . ALA A 1 514 ? 79.946  85.772  -15.389 1.00 35.22  ? 514 ALA A1 C   1 
ATOM 3767 O O   . ALA A 1 514 ? 79.589  84.650  -15.756 1.00 36.01  ? 514 ALA A1 O   1 
ATOM 3768 C CB  . ALA A 1 514 ? 81.160  85.542  -13.214 1.00 31.13  ? 514 ALA A1 CB  1 
ATOM 3769 N N   . SER A 1 515 ? 80.358  86.720  -16.231 1.00 38.44  ? 515 SER A1 N   1 
ATOM 3770 C CA  . SER A 1 515 ? 80.440  86.472  -17.662 1.00 40.33  ? 515 SER A1 CA  1 
ATOM 3771 C C   . SER A 1 515 ? 81.581  85.536  -18.028 1.00 41.74  ? 515 SER A1 C   1 
ATOM 3772 O O   . SER A 1 515 ? 81.591  85.000  -19.142 1.00 43.53  ? 515 SER A1 O   1 
ATOM 3773 C CB  . SER A 1 515 ? 80.596  87.793  -18.415 1.00 40.18  ? 515 SER A1 CB  1 
ATOM 3774 O OG  . SER A 1 515 ? 81.546  88.631  -17.784 1.00 40.98  ? 515 SER A1 OG  1 
ATOM 3775 N N   . ALA A 1 516 ? 82.532  85.328  -17.120 1.00 42.76  ? 516 ALA A1 N   1 
ATOM 3776 C CA  . ALA A 1 516 ? 83.626  84.402  -17.362 1.00 43.21  ? 516 ALA A1 CA  1 
ATOM 3777 C C   . ALA A 1 516 ? 83.130  82.962  -17.340 1.00 42.26  ? 516 ALA A1 C   1 
ATOM 3778 O O   . ALA A 1 516 ? 82.014  82.667  -16.902 1.00 43.92  ? 516 ALA A1 O   1 
ATOM 3779 C CB  . ALA A 1 516 ? 84.726  84.592  -16.320 1.00 43.73  ? 516 ALA A1 CB  1 
ATOM 3780 N N   . ASN A 1 517 ? 83.983  82.061  -17.814 1.00 41.22  ? 517 ASN A1 N   1 
ATOM 3781 C CA  . ASN A 1 517 ? 83.601  80.679  -18.036 1.00 40.78  ? 517 ASN A1 CA  1 
ATOM 3782 C C   . ASN A 1 517 ? 83.476  79.939  -16.703 1.00 36.84  ? 517 ASN A1 C   1 
ATOM 3783 O O   . ASN A 1 517 ? 83.999  80.364  -15.672 1.00 37.83  ? 517 ASN A1 O   1 
ATOM 3784 C CB  . ASN A 1 517 ? 84.627  80.002  -18.950 1.00 46.11  ? 517 ASN A1 CB  1 
ATOM 3785 C CG  . ASN A 1 517 ? 84.095  78.745  -19.606 1.00 49.61  ? 517 ASN A1 CG  1 
ATOM 3786 O OD1 . ASN A 1 517 ? 82.947  78.358  -19.393 1.00 52.63  ? 517 ASN A1 OD1 1 
ATOM 3787 N ND2 . ASN A 1 517 ? 84.930  78.098  -20.413 1.00 49.75  ? 517 ASN A1 ND2 1 
ATOM 3788 N N   . MET A 1 518 ? 82.760  78.820  -16.740 1.00 32.17  ? 518 MET A1 N   1 
ATOM 3789 C CA  . MET A 1 518 ? 82.500  78.035  -15.542 1.00 27.54  ? 518 MET A1 CA  1 
ATOM 3790 C C   . MET A 1 518 ? 83.732  77.226  -15.159 1.00 25.25  ? 518 MET A1 C   1 
ATOM 3791 O O   . MET A 1 518 ? 84.428  76.690  -16.026 1.00 25.96  ? 518 MET A1 O   1 
ATOM 3792 C CB  . MET A 1 518 ? 81.309  77.113  -15.791 1.00 26.69  ? 518 MET A1 CB  1 
ATOM 3793 C CG  . MET A 1 518 ? 80.851  76.302  -14.611 1.00 25.72  ? 518 MET A1 CG  1 
ATOM 3794 S SD  . MET A 1 518 ? 79.199  75.647  -14.890 1.00 26.07  ? 518 MET A1 SD  1 
ATOM 3795 C CE  . MET A 1 518 ? 79.389  74.915  -16.506 1.00 26.22  ? 518 MET A1 CE  1 
ATOM 3796 N N   . SER A 1 519 ? 84.013  77.151  -13.861 1.00 22.02  ? 519 SER A1 N   1 
ATOM 3797 C CA  . SER A 1 519 ? 85.136  76.376  -13.351 1.00 19.31  ? 519 SER A1 CA  1 
ATOM 3798 C C   . SER A 1 519 ? 84.626  75.046  -12.807 1.00 16.05  ? 519 SER A1 C   1 
ATOM 3799 O O   . SER A 1 519 ? 83.753  75.022  -11.935 1.00 14.95  ? 519 SER A1 O   1 
ATOM 3800 C CB  . SER A 1 519 ? 85.880  77.155  -12.270 1.00 21.46  ? 519 SER A1 CB  1 
ATOM 3801 O OG  . SER A 1 519 ? 87.193  76.655  -12.102 1.00 26.18  ? 519 SER A1 OG  1 
ATOM 3802 N N   . ARG A 1 520 ? 85.180  73.949  -13.314 1.00 12.15  ? 520 ARG A1 N   1 
ATOM 3803 C CA  . ARG A 1 520 ? 84.744  72.603  -12.987 1.00 9.87   ? 520 ARG A1 CA  1 
ATOM 3804 C C   . ARG A 1 520 ? 85.922  71.761  -12.522 1.00 9.36   ? 520 ARG A1 C   1 
ATOM 3805 O O   . ARG A 1 520 ? 87.085  72.094  -12.750 1.00 11.35  ? 520 ARG A1 O   1 
ATOM 3806 C CB  . ARG A 1 520 ? 84.081  71.934  -14.196 1.00 9.04   ? 520 ARG A1 CB  1 
ATOM 3807 C CG  . ARG A 1 520 ? 82.797  72.587  -14.647 1.00 8.86   ? 520 ARG A1 CG  1 
ATOM 3808 C CD  . ARG A 1 520 ? 82.425  72.124  -16.036 1.00 7.15   ? 520 ARG A1 CD  1 
ATOM 3809 N NE  . ARG A 1 520 ? 83.500  72.354  -16.995 1.00 5.98   ? 520 ARG A1 NE  1 
ATOM 3810 C CZ  . ARG A 1 520 ? 83.556  71.799  -18.199 1.00 5.33   ? 520 ARG A1 CZ  1 
ATOM 3811 N NH1 . ARG A 1 520 ? 82.601  70.976  -18.592 1.00 5.04   ? 520 ARG A1 NH1 1 
ATOM 3812 N NH2 . ARG A 1 520 ? 84.568  72.061  -19.009 1.00 6.34   ? 520 ARG A1 NH2 1 
ATOM 3813 N N   . ILE A 1 521 ? 85.606  70.655  -11.860 1.00 7.25   ? 521 ILE A1 N   1 
ATOM 3814 C CA  . ILE A 1 521 ? 86.599  69.634  -11.558 1.00 5.70   ? 521 ILE A1 CA  1 
ATOM 3815 C C   . ILE A 1 521 ? 86.775  68.768  -12.793 1.00 7.56   ? 521 ILE A1 C   1 
ATOM 3816 O O   . ILE A 1 521 ? 85.793  68.383  -13.438 1.00 10.03  ? 521 ILE A1 O   1 
ATOM 3817 C CB  . ILE A 1 521 ? 86.165  68.802  -10.339 1.00 3.59   ? 521 ILE A1 CB  1 
ATOM 3818 C CG1 . ILE A 1 521 ? 85.880  69.715  -9.154  1.00 3.35   ? 521 ILE A1 CG1 1 
ATOM 3819 C CG2 . ILE A 1 521 ? 87.231  67.806  -9.955  1.00 2.62   ? 521 ILE A1 CG2 1 
ATOM 3820 C CD1 . ILE A 1 521 ? 85.417  68.989  -7.928  1.00 3.22   ? 521 ILE A1 CD1 1 
ATOM 3821 N N   . VAL A 1 522 ? 88.025  68.471  -13.146 1.00 7.72   ? 522 VAL A1 N   1 
ATOM 3822 C CA  . VAL A 1 522 ? 88.312  67.823  -14.418 1.00 5.72   ? 522 VAL A1 CA  1 
ATOM 3823 C C   . VAL A 1 522 ? 87.948  66.351  -14.334 1.00 6.48   ? 522 VAL A1 C   1 
ATOM 3824 O O   . VAL A 1 522 ? 88.669  65.554  -13.731 1.00 5.24   ? 522 VAL A1 O   1 
ATOM 3825 C CB  . VAL A 1 522 ? 89.780  68.002  -14.826 1.00 4.40   ? 522 VAL A1 CB  1 
ATOM 3826 C CG1 . VAL A 1 522 ? 89.986  67.469  -16.224 1.00 2.46   ? 522 VAL A1 CG1 1 
ATOM 3827 C CG2 . VAL A 1 522 ? 90.163  69.456  -14.747 1.00 4.84   ? 522 VAL A1 CG2 1 
ATOM 3828 N N   . THR A 1 523 ? 86.826  65.988  -14.943 1.00 7.54   ? 523 THR A1 N   1 
ATOM 3829 C CA  . THR A 1 523 ? 86.249  64.658  -14.849 1.00 8.28   ? 523 THR A1 CA  1 
ATOM 3830 C C   . THR A 1 523 ? 86.305  63.982  -16.211 1.00 9.99   ? 523 THR A1 C   1 
ATOM 3831 O O   . THR A 1 523 ? 86.281  64.650  -17.246 1.00 12.09  ? 523 THR A1 O   1 
ATOM 3832 C CB  . THR A 1 523 ? 84.801  64.744  -14.365 1.00 7.25   ? 523 THR A1 CB  1 
ATOM 3833 O OG1 . THR A 1 523 ? 84.691  65.792  -13.400 1.00 6.37   ? 523 THR A1 OG1 1 
ATOM 3834 C CG2 . THR A 1 523 ? 84.373  63.465  -13.699 1.00 7.86   ? 523 THR A1 CG2 1 
ATOM 3835 N N   . TYR A 1 524 ? 86.417  62.660  -16.206 1.00 9.73   ? 524 TYR A1 N   1 
ATOM 3836 C CA  . TYR A 1 524 ? 86.293  61.848  -17.403 1.00 7.45   ? 524 TYR A1 CA  1 
ATOM 3837 C C   . TYR A 1 524 ? 85.606  60.546  -17.022 1.00 6.93   ? 524 TYR A1 C   1 
ATOM 3838 O O   . TYR A 1 524 ? 85.591  60.150  -15.858 1.00 6.20   ? 524 TYR A1 O   1 
ATOM 3839 C CB  . TYR A 1 524 ? 87.656  61.614  -18.067 1.00 5.89   ? 524 TYR A1 CB  1 
ATOM 3840 C CG  . TYR A 1 524 ? 88.615  60.748  -17.296 1.00 6.08   ? 524 TYR A1 CG  1 
ATOM 3841 C CD1 . TYR A 1 524 ? 89.336  61.257  -16.231 1.00 4.95   ? 524 TYR A1 CD1 1 
ATOM 3842 C CD2 . TYR A 1 524 ? 88.813  59.427  -17.646 1.00 6.51   ? 524 TYR A1 CD2 1 
ATOM 3843 C CE1 . TYR A 1 524 ? 90.209  60.470  -15.526 1.00 4.49   ? 524 TYR A1 CE1 1 
ATOM 3844 C CE2 . TYR A 1 524 ? 89.683  58.633  -16.945 1.00 5.32   ? 524 TYR A1 CE2 1 
ATOM 3845 C CZ  . TYR A 1 524 ? 90.378  59.161  -15.890 1.00 4.94   ? 524 TYR A1 CZ  1 
ATOM 3846 O OH  . TYR A 1 524 ? 91.253  58.373  -15.195 1.00 6.18   ? 524 TYR A1 OH  1 
ATOM 3847 N N   . SER A 1 525 ? 85.022  59.878  -18.008 1.00 8.24   ? 525 SER A1 N   1 
ATOM 3848 C CA  . SER A 1 525 ? 84.209  58.706  -17.741 1.00 8.71   ? 525 SER A1 CA  1 
ATOM 3849 C C   . SER A 1 525 ? 84.512  57.606  -18.744 1.00 8.77   ? 525 SER A1 C   1 
ATOM 3850 O O   . SER A 1 525 ? 84.559  57.839  -19.951 1.00 9.34   ? 525 SER A1 O   1 
ATOM 3851 C CB  . SER A 1 525 ? 82.719  59.038  -17.785 1.00 9.53   ? 525 SER A1 CB  1 
ATOM 3852 O OG  . SER A 1 525 ? 81.960  57.872  -18.016 1.00 8.97   ? 525 SER A1 OG  1 
ATOM 3853 N N   . ASP A 1 526 ? 84.710  56.393  -18.229 1.00 8.28   ? 526 ASP A1 N   1 
ATOM 3854 C CA  . ASP A 1 526 ? 84.935  55.218  -19.063 1.00 8.88   ? 526 ASP A1 CA  1 
ATOM 3855 C C   . ASP A 1 526 ? 83.792  54.242  -18.852 1.00 7.98   ? 526 ASP A1 C   1 
ATOM 3856 O O   . ASP A 1 526 ? 83.848  53.417  -17.939 1.00 9.68   ? 526 ASP A1 O   1 
ATOM 3857 C CB  . ASP A 1 526 ? 86.255  54.521  -18.728 1.00 11.99  ? 526 ASP A1 CB  1 
ATOM 3858 C CG  . ASP A 1 526 ? 87.468  55.353  -19.069 1.00 15.81  ? 526 ASP A1 CG  1 
ATOM 3859 O OD1 . ASP A 1 526 ? 87.362  56.592  -19.090 1.00 17.63  ? 526 ASP A1 OD1 1 
ATOM 3860 O OD2 . ASP A 1 526 ? 88.538  54.761  -19.319 1.00 19.10  ? 526 ASP A1 OD2 1 
ATOM 3861 N N   . PHE A 1 527 ? 82.782  54.306  -19.708 1.00 6.51   ? 527 PHE A1 N   1 
ATOM 3862 C CA  . PHE A 1 527 ? 81.648  53.404  -19.629 1.00 5.28   ? 527 PHE A1 CA  1 
ATOM 3863 C C   . PHE A 1 527 ? 81.790  52.343  -20.708 1.00 5.40   ? 527 PHE A1 C   1 
ATOM 3864 O O   . PHE A 1 527 ? 82.576  52.486  -21.642 1.00 6.11   ? 527 PHE A1 O   1 
ATOM 3865 C CB  . PHE A 1 527 ? 80.306  54.155  -19.758 1.00 5.35   ? 527 PHE A1 CB  1 
ATOM 3866 C CG  . PHE A 1 527 ? 80.161  54.970  -21.019 1.00 5.33   ? 527 PHE A1 CG  1 
ATOM 3867 C CD1 . PHE A 1 527 ? 80.660  56.258  -21.095 1.00 5.27   ? 527 PHE A1 CD1 1 
ATOM 3868 C CD2 . PHE A 1 527 ? 79.484  54.459  -22.110 1.00 5.78   ? 527 PHE A1 CD2 1 
ATOM 3869 C CE1 . PHE A 1 527 ? 80.521  56.997  -22.236 1.00 5.43   ? 527 PHE A1 CE1 1 
ATOM 3870 C CE2 . PHE A 1 527 ? 79.342  55.193  -23.251 1.00 5.47   ? 527 PHE A1 CE2 1 
ATOM 3871 C CZ  . PHE A 1 527 ? 79.863  56.462  -23.315 1.00 5.67   ? 527 PHE A1 CZ  1 
ATOM 3872 N N   . TRP A 1 528 ? 81.039  51.257  -20.556 1.00 4.72   ? 528 TRP A1 N   1 
ATOM 3873 C CA  . TRP A 1 528 ? 81.046  50.158  -21.510 1.00 4.75   ? 528 TRP A1 CA  1 
ATOM 3874 C C   . TRP A 1 528 ? 79.765  50.206  -22.324 1.00 5.79   ? 528 TRP A1 C   1 
ATOM 3875 O O   . TRP A 1 528 ? 78.674  50.284  -21.763 1.00 7.43   ? 528 TRP A1 O   1 
ATOM 3876 C CB  . TRP A 1 528 ? 81.158  48.805  -20.817 1.00 3.32   ? 528 TRP A1 CB  1 
ATOM 3877 C CG  . TRP A 1 528 ? 82.466  48.505  -20.224 1.00 3.36   ? 528 TRP A1 CG  1 
ATOM 3878 C CD1 . TRP A 1 528 ? 82.910  48.891  -19.010 1.00 3.60   ? 528 TRP A1 CD1 1 
ATOM 3879 C CD2 . TRP A 1 528 ? 83.504  47.719  -20.802 1.00 4.21   ? 528 TRP A1 CD2 1 
ATOM 3880 N NE1 . TRP A 1 528 ? 84.167  48.411  -18.788 1.00 5.11   ? 528 TRP A1 NE1 1 
ATOM 3881 C CE2 . TRP A 1 528 ? 84.556  47.685  -19.878 1.00 4.83   ? 528 TRP A1 CE2 1 
ATOM 3882 C CE3 . TRP A 1 528 ? 83.652  47.055  -22.018 1.00 3.55   ? 528 TRP A1 CE3 1 
ATOM 3883 C CZ2 . TRP A 1 528 ? 85.741  47.012  -20.130 1.00 4.58   ? 528 TRP A1 CZ2 1 
ATOM 3884 C CZ3 . TRP A 1 528 ? 84.822  46.390  -22.262 1.00 4.38   ? 528 TRP A1 CZ3 1 
ATOM 3885 C CH2 . TRP A 1 528 ? 85.854  46.373  -21.328 1.00 4.24   ? 528 TRP A1 CH2 1 
ATOM 3886 N N   . TRP A 1 529 ? 79.901  50.151  -23.636 1.00 5.69   ? 529 TRP A1 N   1 
ATOM 3887 C CA  . TRP A 1 529 ? 78.767  50.115  -24.537 1.00 3.37   ? 529 TRP A1 CA  1 
ATOM 3888 C C   . TRP A 1 529 ? 78.576  48.686  -25.018 1.00 4.32   ? 529 TRP A1 C   1 
ATOM 3889 O O   . TRP A 1 529 ? 79.530  47.913  -25.054 1.00 4.74   ? 529 TRP A1 O   1 
ATOM 3890 C CB  . TRP A 1 529 ? 79.015  51.064  -25.707 1.00 2.64   ? 529 TRP A1 CB  1 
ATOM 3891 C CG  . TRP A 1 529 ? 78.006  51.017  -26.776 1.00 2.90   ? 529 TRP A1 CG  1 
ATOM 3892 C CD1 . TRP A 1 529 ? 76.825  51.677  -26.810 1.00 2.49   ? 529 TRP A1 CD1 1 
ATOM 3893 C CD2 . TRP A 1 529 ? 78.082  50.265  -27.983 1.00 2.65   ? 529 TRP A1 CD2 1 
ATOM 3894 N NE1 . TRP A 1 529 ? 76.152  51.382  -27.962 1.00 2.00   ? 529 TRP A1 NE1 1 
ATOM 3895 C CE2 . TRP A 1 529 ? 76.908  50.517  -28.703 1.00 2.00   ? 529 TRP A1 CE2 1 
ATOM 3896 C CE3 . TRP A 1 529 ? 79.034  49.401  -28.531 1.00 3.15   ? 529 TRP A1 CE3 1 
ATOM 3897 C CZ2 . TRP A 1 529 ? 76.657  49.936  -29.932 1.00 2.00   ? 529 TRP A1 CZ2 1 
ATOM 3898 C CZ3 . TRP A 1 529 ? 78.783  48.832  -29.751 1.00 2.21   ? 529 TRP A1 CZ3 1 
ATOM 3899 C CH2 . TRP A 1 529 ? 77.605  49.098  -30.436 1.00 2.70   ? 529 TRP A1 CH2 1 
ATOM 3900 N N   . LYS A 1 530 ? 77.341  48.321  -25.350 1.00 4.78   ? 530 LYS A1 N   1 
ATOM 3901 C CA  . LYS A 1 530 ? 77.069  47.028  -25.960 1.00 3.82   ? 530 LYS A1 CA  1 
ATOM 3902 C C   . LYS A 1 530 ? 75.827  47.116  -26.822 1.00 4.10   ? 530 LYS A1 C   1 
ATOM 3903 O O   . LYS A 1 530 ? 74.749  47.442  -26.324 1.00 5.78   ? 530 LYS A1 O   1 
ATOM 3904 C CB  . LYS A 1 530 ? 76.877  45.932  -24.919 1.00 3.71   ? 530 LYS A1 CB  1 
ATOM 3905 C CG  . LYS A 1 530 ? 76.457  44.619  -25.540 1.00 4.16   ? 530 LYS A1 CG  1 
ATOM 3906 C CD  . LYS A 1 530 ? 76.677  43.439  -24.633 1.00 6.14   ? 530 LYS A1 CD  1 
ATOM 3907 C CE  . LYS A 1 530 ? 75.700  43.440  -23.503 1.00 7.00   ? 530 LYS A1 CE  1 
ATOM 3908 N NZ  . LYS A 1 530 ? 75.913  42.305  -22.582 1.00 8.83   ? 530 LYS A1 NZ  1 
ATOM 3909 N N   . GLY A 1 531 ? 75.978  46.802  -28.106 1.00 4.23   ? 531 GLY A1 N   1 
ATOM 3910 C CA  . GLY A 1 531 ? 74.860  46.760  -29.017 1.00 4.47   ? 531 GLY A1 CA  1 
ATOM 3911 C C   . GLY A 1 531 ? 74.614  45.333  -29.463 1.00 5.14   ? 531 GLY A1 C   1 
ATOM 3912 O O   . GLY A 1 531 ? 75.433  44.448  -29.245 1.00 6.70   ? 531 GLY A1 O   1 
ATOM 3913 N N   . LYS A 1 532 ? 73.453  45.124  -30.067 1.00 4.31   ? 532 LYS A1 N   1 
ATOM 3914 C CA  . LYS A 1 532 ? 73.105  43.829  -30.639 1.00 4.50   ? 532 LYS A1 CA  1 
ATOM 3915 C C   . LYS A 1 532 ? 72.256  44.095  -31.865 1.00 5.65   ? 532 LYS A1 C   1 
ATOM 3916 O O   . LYS A 1 532 ? 71.099  44.501  -31.744 1.00 8.76   ? 532 LYS A1 O   1 
ATOM 3917 C CB  . LYS A 1 532 ? 72.361  42.949  -29.645 1.00 5.90   ? 532 LYS A1 CB  1 
ATOM 3918 C CG  . LYS A 1 532 ? 71.846  41.655  -30.240 1.00 8.68   ? 532 LYS A1 CG  1 
ATOM 3919 C CD  . LYS A 1 532 ? 71.570  40.633  -29.166 1.00 11.53  ? 532 LYS A1 CD  1 
ATOM 3920 C CE  . LYS A 1 532 ? 70.567  41.153  -28.163 1.00 16.13  ? 532 LYS A1 CE  1 
ATOM 3921 N NZ  . LYS A 1 532 ? 70.405  40.240  -27.000 1.00 20.97  ? 532 LYS A1 NZ  1 
ATOM 3922 N N   . LEU A 1 533 ? 72.833  43.882  -33.033 1.00 4.55   ? 533 LEU A1 N   1 
ATOM 3923 C CA  . LEU A 1 533 ? 72.142  44.044  -34.298 1.00 4.07   ? 533 LEU A1 CA  1 
ATOM 3924 C C   . LEU A 1 533 ? 71.777  42.669  -34.823 1.00 4.74   ? 533 LEU A1 C   1 
ATOM 3925 O O   . LEU A 1 533 ? 72.629  41.783  -34.890 1.00 5.52   ? 533 LEU A1 O   1 
ATOM 3926 C CB  . LEU A 1 533 ? 73.027  44.772  -35.300 1.00 3.21   ? 533 LEU A1 CB  1 
ATOM 3927 C CG  . LEU A 1 533 ? 72.427  45.476  -36.497 1.00 2.55   ? 533 LEU A1 CG  1 
ATOM 3928 C CD1 . LEU A 1 533 ? 71.528  46.548  -36.041 1.00 2.10   ? 533 LEU A1 CD1 1 
ATOM 3929 C CD2 . LEU A 1 533 ? 73.525  46.083  -37.270 1.00 2.00   ? 533 LEU A1 CD2 1 
ATOM 3930 N N   . VAL A 1 534 ? 70.517  42.490  -35.185 1.00 4.11   ? 534 VAL A1 N   1 
ATOM 3931 C CA  . VAL A 1 534 ? 70.017  41.229  -35.701 1.00 3.50   ? 534 VAL A1 CA  1 
ATOM 3932 C C   . VAL A 1 534 ? 69.702  41.402  -37.177 1.00 5.17   ? 534 VAL A1 C   1 
ATOM 3933 O O   . VAL A 1 534 ? 68.968  42.318  -37.556 1.00 5.67   ? 534 VAL A1 O   1 
ATOM 3934 C CB  . VAL A 1 534 ? 68.776  40.765  -34.930 1.00 2.42   ? 534 VAL A1 CB  1 
ATOM 3935 C CG1 . VAL A 1 534 ? 68.195  39.545  -35.566 1.00 2.71   ? 534 VAL A1 CG1 1 
ATOM 3936 C CG2 . VAL A 1 534 ? 69.128  40.489  -33.503 1.00 2.30   ? 534 VAL A1 CG2 1 
ATOM 3937 N N   . PHE A 1 535 ? 70.266  40.531  -38.003 1.00 6.81   ? 535 PHE A1 N   1 
ATOM 3938 C CA  . PHE A 1 535 ? 69.952  40.451  -39.418 1.00 7.69   ? 535 PHE A1 CA  1 
ATOM 3939 C C   . PHE A 1 535 ? 69.174  39.181  -39.697 1.00 8.87   ? 535 PHE A1 C   1 
ATOM 3940 O O   . PHE A 1 535 ? 68.849  38.412  -38.797 1.00 9.27   ? 535 PHE A1 O   1 
ATOM 3941 C CB  . PHE A 1 535 ? 71.216  40.461  -40.270 1.00 7.89   ? 535 PHE A1 CB  1 
ATOM 3942 C CG  . PHE A 1 535 ? 71.909  41.768  -40.300 1.00 8.94   ? 535 PHE A1 CG  1 
ATOM 3943 C CD1 . PHE A 1 535 ? 72.879  42.064  -39.373 1.00 7.88   ? 535 PHE A1 CD1 1 
ATOM 3944 C CD2 . PHE A 1 535 ? 71.598  42.700  -41.263 1.00 8.53   ? 535 PHE A1 CD2 1 
ATOM 3945 C CE1 . PHE A 1 535 ? 73.516  43.261  -39.408 1.00 8.04   ? 535 PHE A1 CE1 1 
ATOM 3946 C CE2 . PHE A 1 535 ? 72.239  43.895  -41.304 1.00 8.28   ? 535 PHE A1 CE2 1 
ATOM 3947 C CZ  . PHE A 1 535 ? 73.192  44.180  -40.371 1.00 8.53   ? 535 PHE A1 CZ  1 
ATOM 3948 N N   . LYS A 1 536 ? 68.880  38.971  -40.972 1.00 9.77   ? 536 LYS A1 N   1 
ATOM 3949 C CA  . LYS A 1 536 ? 68.204  37.765  -41.428 1.00 11.14  ? 536 LYS A1 CA  1 
ATOM 3950 C C   . LYS A 1 536 ? 68.555  37.583  -42.893 1.00 10.01  ? 536 LYS A1 C   1 
ATOM 3951 O O   . LYS A 1 536 ? 68.124  38.372  -43.733 1.00 9.95   ? 536 LYS A1 O   1 
ATOM 3952 C CB  . LYS A 1 536 ? 66.695  37.866  -41.239 1.00 15.97  ? 536 LYS A1 CB  1 
ATOM 3953 C CG  . LYS A 1 536 ? 65.943  36.697  -41.822 1.00 23.61  ? 536 LYS A1 CG  1 
ATOM 3954 C CD  . LYS A 1 536 ? 64.452  36.863  -41.655 1.00 31.28  ? 536 LYS A1 CD  1 
ATOM 3955 C CE  . LYS A 1 536 ? 64.079  36.979  -40.189 1.00 35.45  ? 536 LYS A1 CE  1 
ATOM 3956 N NZ  . LYS A 1 536 ? 64.643  35.868  -39.377 1.00 39.35  ? 536 LYS A1 NZ  1 
ATOM 3957 N N   . ALA A 1 537 ? 69.330  36.556  -43.201 1.00 8.47   ? 537 ALA A1 N   1 
ATOM 3958 C CA  . ALA A 1 537 ? 69.848  36.381  -44.541 1.00 7.94   ? 537 ALA A1 CA  1 
ATOM 3959 C C   . ALA A 1 537 ? 69.427  35.036  -45.106 1.00 9.31   ? 537 ALA A1 C   1 
ATOM 3960 O O   . ALA A 1 537 ? 69.176  34.078  -44.376 1.00 9.69   ? 537 ALA A1 O   1 
ATOM 3961 C CB  . ALA A 1 537 ? 71.367  36.502  -44.556 1.00 5.85   ? 537 ALA A1 CB  1 
ATOM 3962 N N   . LYS A 1 538 ? 69.372  34.976  -46.430 1.00 11.93  ? 538 LYS A1 N   1 
ATOM 3963 C CA  . LYS A 1 538 ? 68.950  33.792  -47.157 1.00 13.87  ? 538 LYS A1 CA  1 
ATOM 3964 C C   . LYS A 1 538 ? 70.147  33.178  -47.856 1.00 14.38  ? 538 LYS A1 C   1 
ATOM 3965 O O   . LYS A 1 538 ? 70.822  33.856  -48.632 1.00 16.84  ? 538 LYS A1 O   1 
ATOM 3966 C CB  . LYS A 1 538 ? 67.876  34.141  -48.180 1.00 15.98  ? 538 LYS A1 CB  1 
ATOM 3967 C CG  . LYS A 1 538 ? 67.508  32.991  -49.069 1.00 22.06  ? 538 LYS A1 CG  1 
ATOM 3968 C CD  . LYS A 1 538 ? 66.380  33.359  -49.991 1.00 27.21  ? 538 LYS A1 CD  1 
ATOM 3969 C CE  . LYS A 1 538 ? 65.707  32.107  -50.499 1.00 30.91  ? 538 LYS A1 CE  1 
ATOM 3970 N NZ  . LYS A 1 538 ? 65.396  31.190  -49.371 1.00 37.55  ? 538 LYS A1 NZ  1 
ATOM 3971 N N   . LEU A 1 539 ? 70.385  31.894  -47.600 1.00 14.46  ? 539 LEU A1 N   1 
ATOM 3972 C CA  . LEU A 1 539 ? 71.526  31.188  -48.166 1.00 14.58  ? 539 LEU A1 CA  1 
ATOM 3973 C C   . LEU A 1 539 ? 71.410  31.062  -49.678 1.00 15.45  ? 539 LEU A1 C   1 
ATOM 3974 O O   . LEU A 1 539 ? 70.342  30.754  -50.211 1.00 16.91  ? 539 LEU A1 O   1 
ATOM 3975 C CB  . LEU A 1 539 ? 71.633  29.800  -47.552 1.00 14.10  ? 539 LEU A1 CB  1 
ATOM 3976 C CG  . LEU A 1 539 ? 71.779  29.768  -46.040 1.00 14.94  ? 539 LEU A1 CG  1 
ATOM 3977 C CD1 . LEU A 1 539 ? 71.126  28.541  -45.460 1.00 14.90  ? 539 LEU A1 CD1 1 
ATOM 3978 C CD2 . LEU A 1 539 ? 73.219  29.800  -45.669 1.00 15.34  ? 539 LEU A1 CD2 1 
ATOM 3979 N N   . ARG A 1 540 ? 72.522  31.293  -50.368 1.00 15.76  ? 540 ARG A1 N   1 
ATOM 3980 C CA  . ARG A 1 540 ? 72.517  31.268  -51.819 1.00 16.83  ? 540 ARG A1 CA  1 
ATOM 3981 C C   . ARG A 1 540 ? 72.491  29.839  -52.334 1.00 16.89  ? 540 ARG A1 C   1 
ATOM 3982 O O   . ARG A 1 540 ? 72.809  28.887  -51.618 1.00 16.92  ? 540 ARG A1 O   1 
ATOM 3983 C CB  . ARG A 1 540 ? 73.735  31.998  -52.379 1.00 19.16  ? 540 ARG A1 CB  1 
ATOM 3984 C CG  . ARG A 1 540 ? 75.005  31.200  -52.340 1.00 22.00  ? 540 ARG A1 CG  1 
ATOM 3985 C CD  . ARG A 1 540 ? 76.072  31.792  -53.226 1.00 22.25  ? 540 ARG A1 CD  1 
ATOM 3986 N NE  . ARG A 1 540 ? 77.248  30.940  -53.244 1.00 21.54  ? 540 ARG A1 NE  1 
ATOM 3987 C CZ  . ARG A 1 540 ? 77.424  29.949  -54.104 1.00 21.31  ? 540 ARG A1 CZ  1 
ATOM 3988 N NH1 . ARG A 1 540 ? 76.504  29.701  -55.020 1.00 21.17  ? 540 ARG A1 NH1 1 
ATOM 3989 N NH2 . ARG A 1 540 ? 78.523  29.214  -54.059 1.00 22.20  ? 540 ARG A1 NH2 1 
ATOM 3990 N N   . ALA A 1 541 ? 72.086  29.696  -53.586 1.00 18.36  ? 541 ALA A1 N   1 
ATOM 3991 C CA  . ALA A 1 541 ? 72.010  28.413  -54.258 1.00 19.09  ? 541 ALA A1 CA  1 
ATOM 3992 C C   . ALA A 1 541 ? 72.990  28.380  -55.420 1.00 19.88  ? 541 ALA A1 C   1 
ATOM 3993 O O   . ALA A 1 541 ? 73.651  29.369  -55.742 1.00 20.39  ? 541 ALA A1 O   1 
ATOM 3994 C CB  . ALA A 1 541 ? 70.585  28.149  -54.746 1.00 19.59  ? 541 ALA A1 CB  1 
ATOM 3995 N N   . SER A 1 542 ? 73.082  27.221  -56.054 1.00 19.57  ? 542 SER A1 N   1 
ATOM 3996 C CA  . SER A 1 542 ? 73.942  27.024  -57.211 1.00 21.22  ? 542 SER A1 CA  1 
ATOM 3997 C C   . SER A 1 542 ? 73.068  26.869  -58.443 1.00 20.75  ? 542 SER A1 C   1 
ATOM 3998 O O   . SER A 1 542 ? 72.497  25.799  -58.666 1.00 20.17  ? 542 SER A1 O   1 
ATOM 3999 C CB  . SER A 1 542 ? 74.828  25.797  -57.030 1.00 23.72  ? 542 SER A1 CB  1 
ATOM 4000 O OG  . SER A 1 542 ? 75.283  25.323  -58.280 1.00 27.57  ? 542 SER A1 OG  1 
ATOM 4001 N N   . HIS A 1 543 ? 72.966  27.930  -59.237 1.00 21.98  ? 543 HIS A1 N   1 
ATOM 4002 C CA  . HIS A 1 543 ? 72.153  27.898  -60.440 1.00 24.20  ? 543 HIS A1 CA  1 
ATOM 4003 C C   . HIS A 1 543 ? 72.921  27.506  -61.688 1.00 21.57  ? 543 HIS A1 C   1 
ATOM 4004 O O   . HIS A 1 543 ? 72.349  26.857  -62.565 1.00 22.69  ? 543 HIS A1 O   1 
ATOM 4005 C CB  . HIS A 1 543 ? 71.505  29.265  -60.684 1.00 31.15  ? 543 HIS A1 CB  1 
ATOM 4006 C CG  . HIS A 1 543 ? 70.862  29.852  -59.471 1.00 36.91  ? 543 HIS A1 CG  1 
ATOM 4007 N ND1 . HIS A 1 543 ? 71.518  30.725  -58.632 1.00 38.26  ? 543 HIS A1 ND1 1 
ATOM 4008 C CD2 . HIS A 1 543 ? 69.619  29.698  -58.958 1.00 38.13  ? 543 HIS A1 CD2 1 
ATOM 4009 C CE1 . HIS A 1 543 ? 70.709  31.081  -57.651 1.00 39.97  ? 543 HIS A1 CE1 1 
ATOM 4010 N NE2 . HIS A 1 543 ? 69.550  30.473  -57.826 1.00 39.83  ? 543 HIS A1 NE2 1 
ATOM 4011 N N   . THR A 1 544 ? 74.189  27.874  -61.786 1.00 17.65  ? 544 THR A1 N   1 
ATOM 4012 C CA  . THR A 1 544 ? 74.978  27.696  -62.989 1.00 15.72  ? 544 THR A1 CA  1 
ATOM 4013 C C   . THR A 1 544 ? 75.935  26.528  -62.816 1.00 15.55  ? 544 THR A1 C   1 
ATOM 4014 O O   . THR A 1 544 ? 76.146  26.021  -61.714 1.00 16.79  ? 544 THR A1 O   1 
ATOM 4015 C CB  . THR A 1 544 ? 75.737  28.984  -63.311 1.00 14.34  ? 544 THR A1 CB  1 
ATOM 4016 O OG1 . THR A 1 544 ? 76.652  29.272  -62.253 1.00 15.30  ? 544 THR A1 OG1 1 
ATOM 4017 C CG2 . THR A 1 544 ? 74.777  30.129  -63.417 1.00 13.16  ? 544 THR A1 CG2 1 
ATOM 4018 N N   . TRP A 1 545 ? 76.498  26.090  -63.941 1.00 12.77  ? 545 TRP A1 N   1 
ATOM 4019 C CA  . TRP A 1 545 ? 77.462  24.997  -63.947 1.00 10.12  ? 545 TRP A1 CA  1 
ATOM 4020 C C   . TRP A 1 545 ? 78.770  25.402  -63.283 1.00 9.96   ? 545 TRP A1 C   1 
ATOM 4021 O O   . TRP A 1 545 ? 79.335  24.636  -62.503 1.00 8.62   ? 545 TRP A1 O   1 
ATOM 4022 C CB  . TRP A 1 545 ? 77.702  24.544  -65.390 1.00 9.04   ? 545 TRP A1 CB  1 
ATOM 4023 C CG  . TRP A 1 545 ? 78.853  23.600  -65.613 1.00 8.12   ? 545 TRP A1 CG  1 
ATOM 4024 C CD1 . TRP A 1 545 ? 80.158  23.928  -65.831 1.00 7.62   ? 545 TRP A1 CD1 1 
ATOM 4025 C CD2 . TRP A 1 545 ? 78.783  22.180  -65.706 1.00 8.61   ? 545 TRP A1 CD2 1 
ATOM 4026 N NE1 . TRP A 1 545 ? 80.907  22.801  -66.014 1.00 9.63   ? 545 TRP A1 NE1 1 
ATOM 4027 C CE2 . TRP A 1 545 ? 80.082  21.712  -65.946 1.00 8.84   ? 545 TRP A1 CE2 1 
ATOM 4028 C CE3 . TRP A 1 545 ? 77.748  21.257  -65.592 1.00 7.99   ? 545 TRP A1 CE3 1 
ATOM 4029 C CZ2 . TRP A 1 545 ? 80.371  20.365  -66.071 1.00 7.72   ? 545 TRP A1 CZ2 1 
ATOM 4030 C CZ3 . TRP A 1 545 ? 78.036  19.927  -65.719 1.00 8.10   ? 545 TRP A1 CZ3 1 
ATOM 4031 C CH2 . TRP A 1 545 ? 79.334  19.491  -65.958 1.00 7.77   ? 545 TRP A1 CH2 1 
ATOM 4032 N N   . ASN A 1 546 ? 79.255  26.582  -63.570 1.00 9.31   ? 546 ASN A1 N   1 
ATOM 4033 C CA  . ASN A 1 546 ? 80.596  26.994  -63.203 1.00 8.28   ? 546 ASN A1 CA  1 
ATOM 4034 C C   . ASN A 1 546 ? 80.632  27.568  -61.795 1.00 9.75   ? 546 ASN A1 C   1 
ATOM 4035 O O   . ASN A 1 546 ? 79.622  28.056  -61.288 1.00 11.33  ? 546 ASN A1 O   1 
ATOM 4036 C CB  . ASN A 1 546 ? 81.097  28.027  -64.201 1.00 6.89   ? 546 ASN A1 CB  1 
ATOM 4037 C CG  . ASN A 1 546 ? 80.196  29.210  -64.292 1.00 6.25   ? 546 ASN A1 CG  1 
ATOM 4038 O OD1 . ASN A 1 546 ? 79.031  29.141  -63.935 1.00 6.18   ? 546 ASN A1 OD1 1 
ATOM 4039 N ND2 . ASN A 1 546 ? 80.730  30.319  -64.766 1.00 6.76   ? 546 ASN A1 ND2 1 
ATOM 4040 N N   . PRO A 1 547 ? 81.777  27.518  -61.123 1.00 8.70   ? 547 PRO A1 N   1 
ATOM 4041 C CA  . PRO A 1 547 ? 81.885  28.175  -59.824 1.00 7.13   ? 547 PRO A1 CA  1 
ATOM 4042 C C   . PRO A 1 547 ? 81.917  29.684  -59.954 1.00 7.93   ? 547 PRO A1 C   1 
ATOM 4043 O O   . PRO A 1 547 ? 82.539  30.245  -60.855 1.00 7.64   ? 547 PRO A1 O   1 
ATOM 4044 C CB  . PRO A 1 547 ? 83.213  27.650  -59.271 1.00 6.63   ? 547 PRO A1 CB  1 
ATOM 4045 C CG  . PRO A 1 547 ? 83.961  27.222  -60.429 1.00 8.37   ? 547 PRO A1 CG  1 
ATOM 4046 C CD  . PRO A 1 547 ? 82.966  26.701  -61.404 1.00 8.18   ? 547 PRO A1 CD  1 
ATOM 4047 N N   . ILE A 1 548 ? 81.216  30.338  -59.037 1.00 7.89   ? 548 ILE A1 N   1 
ATOM 4048 C CA  . ILE A 1 548 ? 81.174  31.790  -58.978 1.00 7.40   ? 548 ILE A1 CA  1 
ATOM 4049 C C   . ILE A 1 548 ? 82.364  32.323  -58.199 1.00 10.87  ? 548 ILE A1 C   1 
ATOM 4050 O O   . ILE A 1 548 ? 83.103  31.562  -57.572 1.00 13.48  ? 548 ILE A1 O   1 
ATOM 4051 C CB  . ILE A 1 548 ? 79.870  32.275  -58.344 1.00 4.25   ? 548 ILE A1 CB  1 
ATOM 4052 C CG1 . ILE A 1 548 ? 79.797  31.753  -56.924 1.00 2.96   ? 548 ILE A1 CG1 1 
ATOM 4053 C CG2 . ILE A 1 548 ? 78.698  31.796  -59.144 1.00 2.00   ? 548 ILE A1 CG2 1 
ATOM 4054 C CD1 . ILE A 1 548 ? 78.811  32.454  -56.107 1.00 3.49   ? 548 ILE A1 CD1 1 
ATOM 4055 N N   . GLN A 1 549 ? 82.551  33.638  -58.239 1.00 12.29  ? 549 GLN A1 N   1 
ATOM 4056 C CA  . GLN A 1 549 ? 83.621  34.295  -57.508 1.00 12.94  ? 549 GLN A1 CA  1 
ATOM 4057 C C   . GLN A 1 549 ? 83.342  34.307  -56.013 1.00 11.68  ? 549 GLN A1 C   1 
ATOM 4058 O O   . GLN A 1 549 ? 82.245  34.655  -55.575 1.00 12.99  ? 549 GLN A1 O   1 
ATOM 4059 C CB  . GLN A 1 549 ? 83.777  35.725  -58.011 1.00 15.77  ? 549 GLN A1 CB  1 
ATOM 4060 C CG  . GLN A 1 549 ? 84.831  36.533  -57.318 1.00 20.66  ? 549 GLN A1 CG  1 
ATOM 4061 C CD  . GLN A 1 549 ? 84.813  37.962  -57.777 1.00 23.29  ? 549 GLN A1 CD  1 
ATOM 4062 O OE1 . GLN A 1 549 ? 83.748  38.545  -57.958 1.00 25.71  ? 549 GLN A1 OE1 1 
ATOM 4063 N NE2 . GLN A 1 549 ? 85.986  38.539  -57.976 1.00 25.15  ? 549 GLN A1 NE2 1 
ATOM 4064 N N   . GLN A 1 550 ? 84.343  33.927  -55.226 1.00 9.92   ? 550 GLN A1 N   1 
ATOM 4065 C CA  . GLN A 1 550 ? 84.235  33.927  -53.778 1.00 10.13  ? 550 GLN A1 CA  1 
ATOM 4066 C C   . GLN A 1 550 ? 85.370  34.738  -53.177 1.00 9.87   ? 550 GLN A1 C   1 
ATOM 4067 O O   . GLN A 1 550 ? 86.496  34.728  -53.674 1.00 13.38  ? 550 GLN A1 O   1 
ATOM 4068 C CB  . GLN A 1 550 ? 84.268  32.509  -53.199 1.00 10.74  ? 550 GLN A1 CB  1 
ATOM 4069 C CG  . GLN A 1 550 ? 83.253  31.556  -53.767 1.00 13.48  ? 550 GLN A1 CG  1 
ATOM 4070 C CD  . GLN A 1 550 ? 81.870  31.761  -53.203 1.00 13.96  ? 550 GLN A1 CD  1 
ATOM 4071 O OE1 . GLN A 1 550 ? 81.128  32.631  -53.651 1.00 15.73  ? 550 GLN A1 OE1 1 
ATOM 4072 N NE2 . GLN A 1 550 ? 81.507  30.950  -52.227 1.00 14.64  ? 550 GLN A1 NE2 1 
ATOM 4073 N N   . MET A 1 551 ? 85.059  35.433  -52.086 1.00 8.60   ? 551 MET A1 N   1 
ATOM 4074 C CA  . MET A 1 551 ? 86.062  36.160  -51.320 1.00 6.36   ? 551 MET A1 CA  1 
ATOM 4075 C C   . MET A 1 551 ? 86.914  35.163  -50.554 1.00 6.74   ? 551 MET A1 C   1 
ATOM 4076 O O   . MET A 1 551 ? 86.381  34.306  -49.846 1.00 6.47   ? 551 MET A1 O   1 
ATOM 4077 C CB  . MET A 1 551 ? 85.393  37.140  -50.362 1.00 7.09   ? 551 MET A1 CB  1 
ATOM 4078 C CG  . MET A 1 551 ? 86.273  37.610  -49.218 1.00 6.98   ? 551 MET A1 CG  1 
ATOM 4079 S SD  . MET A 1 551 ? 85.312  38.376  -47.902 1.00 8.24   ? 551 MET A1 SD  1 
ATOM 4080 C CE  . MET A 1 551 ? 86.551  38.533  -46.622 1.00 4.94   ? 551 MET A1 CE  1 
ATOM 4081 N N   . SER A 1 552 ? 88.230  35.268  -50.688 1.00 6.94   ? 552 SER A1 N   1 
ATOM 4082 C CA  . SER A 1 552 ? 89.138  34.326  -50.060 1.00 6.69   ? 552 SER A1 CA  1 
ATOM 4083 C C   . SER A 1 552 ? 90.313  35.073  -49.454 1.00 6.18   ? 552 SER A1 C   1 
ATOM 4084 O O   . SER A 1 552 ? 90.409  36.299  -49.529 1.00 8.01   ? 552 SER A1 O   1 
ATOM 4085 C CB  . SER A 1 552 ? 89.640  33.284  -51.057 1.00 6.95   ? 552 SER A1 CB  1 
ATOM 4086 O OG  . SER A 1 552 ? 90.803  32.648  -50.567 1.00 8.92   ? 552 SER A1 OG  1 
ATOM 4087 N N   . ILE A 1 553 ? 91.210  34.313  -48.840 1.00 5.23   ? 553 ILE A1 N   1 
ATOM 4088 C CA  . ILE A 1 553 ? 92.478  34.821  -48.337 1.00 4.80   ? 553 ILE A1 CA  1 
ATOM 4089 C C   . ILE A 1 553 ? 93.578  34.101  -49.104 1.00 6.09   ? 553 ILE A1 C   1 
ATOM 4090 O O   . ILE A 1 553 ? 93.506  32.884  -49.314 1.00 7.14   ? 553 ILE A1 O   1 
ATOM 4091 C CB  . ILE A 1 553 ? 92.601  34.633  -46.815 1.00 3.36   ? 553 ILE A1 CB  1 
ATOM 4092 C CG1 . ILE A 1 553 ? 93.984  35.002  -46.296 1.00 2.00   ? 553 ILE A1 CG1 1 
ATOM 4093 C CG2 . ILE A 1 553 ? 92.241  33.224  -46.390 1.00 2.00   ? 553 ILE A1 CG2 1 
ATOM 4094 C CD1 . ILE A 1 553 ? 94.053  35.031  -44.801 1.00 2.07   ? 553 ILE A1 CD1 1 
ATOM 4095 N N   . ASN A 1 554 ? 94.553  34.858  -49.593 1.00 7.07   ? 554 ASN A1 N   1 
ATOM 4096 C CA  . ASN A 1 554 ? 95.642  34.253  -50.342 1.00 9.83   ? 554 ASN A1 CA  1 
ATOM 4097 C C   . ASN A 1 554 ? 96.964  34.903  -49.973 1.00 11.25  ? 554 ASN A1 C   1 
ATOM 4098 O O   . ASN A 1 554 ? 97.056  35.565  -48.939 1.00 12.72  ? 554 ASN A1 O   1 
ATOM 4099 C CB  . ASN A 1 554 ? 95.367  34.328  -51.843 1.00 12.27  ? 554 ASN A1 CB  1 
ATOM 4100 C CG  . ASN A 1 554 ? 94.797  35.647  -52.258 1.00 14.98  ? 554 ASN A1 CG  1 
ATOM 4101 O OD1 . ASN A 1 554 ? 94.721  36.564  -51.465 1.00 16.07  ? 554 ASN A1 OD1 1 
ATOM 4102 N ND2 . ASN A 1 554 ? 94.372  35.746  -53.507 1.00 16.88  ? 554 ASN A1 ND2 1 
ATOM 4103 N N   . VAL A 1 555 ? 97.998  34.687  -50.787 1.00 13.24  ? 555 VAL A1 N   1 
ATOM 4104 C CA  . VAL A 1 555 ? 99.359  35.011  -50.372 1.00 14.43  ? 555 VAL A1 CA  1 
ATOM 4105 C C   . VAL A 1 555 ? 99.586  36.515  -50.336 1.00 14.61  ? 555 VAL A1 C   1 
ATOM 4106 O O   . VAL A 1 555 ? 100.325 37.017  -49.483 1.00 14.62  ? 555 VAL A1 O   1 
ATOM 4107 C CB  . VAL A 1 555 ? 100.367 34.310  -51.296 1.00 14.22  ? 555 VAL A1 CB  1 
ATOM 4108 C CG1 . VAL A 1 555 ? 101.738 34.278  -50.655 1.00 14.53  ? 555 VAL A1 CG1 1 
ATOM 4109 C CG2 . VAL A 1 555 ? 99.897  32.912  -51.618 1.00 15.58  ? 555 VAL A1 CG2 1 
ATOM 4110 N N   . ASP A 1 556 ? 98.946  37.259  -51.227 1.00 16.59  ? 556 ASP A1 N   1 
ATOM 4111 C CA  . ASP A 1 556 ? 99.161  38.693  -51.305 1.00 19.94  ? 556 ASP A1 CA  1 
ATOM 4112 C C   . ASP A 1 556 ? 98.265  39.490  -50.371 1.00 19.38  ? 556 ASP A1 C   1 
ATOM 4113 O O   . ASP A 1 556 ? 98.358  40.720  -50.354 1.00 22.98  ? 556 ASP A1 O   1 
ATOM 4114 C CB  . ASP A 1 556 ? 98.964  39.171  -52.742 1.00 25.08  ? 556 ASP A1 CB  1 
ATOM 4115 C CG  . ASP A 1 556 ? 97.796  38.504  -53.415 1.00 28.90  ? 556 ASP A1 CG  1 
ATOM 4116 O OD1 . ASP A 1 556 ? 97.611  38.705  -54.633 1.00 30.61  ? 556 ASP A1 OD1 1 
ATOM 4117 O OD2 . ASP A 1 556 ? 97.060  37.775  -52.724 1.00 31.34  ? 556 ASP A1 OD2 1 
ATOM 4118 N N   . ASN A 1 557 ? 97.396  38.838  -49.601 1.00 16.03  ? 557 ASN A1 N   1 
ATOM 4119 C CA  . ASN A 1 557 ? 96.674  39.565  -48.564 1.00 13.10  ? 557 ASN A1 CA  1 
ATOM 4120 C C   . ASN A 1 557 ? 96.492  38.753  -47.290 1.00 11.65  ? 557 ASN A1 C   1 
ATOM 4121 O O   . ASN A 1 557 ? 95.524  38.983  -46.566 1.00 11.72  ? 557 ASN A1 O   1 
ATOM 4122 C CB  . ASN A 1 557 ? 95.306  40.041  -49.053 1.00 11.13  ? 557 ASN A1 CB  1 
ATOM 4123 C CG  . ASN A 1 557 ? 94.441  38.922  -49.567 1.00 8.97   ? 557 ASN A1 CG  1 
ATOM 4124 O OD1 . ASN A 1 557 ? 93.863  38.158  -48.805 1.00 10.53  ? 557 ASN A1 OD1 1 
ATOM 4125 N ND2 . ASN A 1 557 ? 94.335  38.826  -50.881 1.00 7.77   ? 557 ASN A1 ND2 1 
ATOM 4126 N N   . GLN A 1 558 ? 97.388  37.818  -46.989 1.00 11.48  ? 558 GLN A1 N   1 
ATOM 4127 C CA  . GLN A 1 558 ? 97.258  37.057  -45.755 1.00 11.29  ? 558 GLN A1 CA  1 
ATOM 4128 C C   . GLN A 1 558 ? 97.595  37.877  -44.522 1.00 10.04  ? 558 GLN A1 C   1 
ATOM 4129 O O   . GLN A 1 558 ? 97.235  37.469  -43.415 1.00 7.67   ? 558 GLN A1 O   1 
ATOM 4130 C CB  . GLN A 1 558 ? 98.152  35.823  -45.801 1.00 12.23  ? 558 GLN A1 CB  1 
ATOM 4131 C CG  . GLN A 1 558 ? 99.557  36.124  -46.245 1.00 15.08  ? 558 GLN A1 CG  1 
ATOM 4132 C CD  . GLN A 1 558 ? 100.453 34.926  -46.167 1.00 17.47  ? 558 GLN A1 CD  1 
ATOM 4133 O OE1 . GLN A 1 558 ? 100.070 33.891  -45.639 1.00 18.39  ? 558 GLN A1 OE1 1 
ATOM 4134 N NE2 . GLN A 1 558 ? 101.656 35.053  -46.701 1.00 20.06  ? 558 GLN A1 NE2 1 
ATOM 4135 N N   . PHE A 1 559 ? 98.264  39.012  -44.680 1.00 11.24  ? 559 PHE A1 N   1 
ATOM 4136 C CA  . PHE A 1 559 ? 98.754  39.784  -43.552 1.00 11.59  ? 559 PHE A1 CA  1 
ATOM 4137 C C   . PHE A 1 559 ? 97.884  40.983  -43.226 1.00 11.09  ? 559 PHE A1 C   1 
ATOM 4138 O O   . PHE A 1 559 ? 98.227  41.750  -42.325 1.00 12.48  ? 559 PHE A1 O   1 
ATOM 4139 C CB  . PHE A 1 559 ? 100.186 40.232  -43.822 1.00 13.01  ? 559 PHE A1 CB  1 
ATOM 4140 C CG  . PHE A 1 559 ? 101.159 39.099  -43.882 1.00 13.20  ? 559 PHE A1 CG  1 
ATOM 4141 C CD1 . PHE A 1 559 ? 100.997 37.995  -43.065 1.00 13.54  ? 559 PHE A1 CD1 1 
ATOM 4142 C CD2 . PHE A 1 559 ? 102.225 39.131  -44.757 1.00 12.47  ? 559 PHE A1 CD2 1 
ATOM 4143 C CE1 . PHE A 1 559 ? 101.882 36.946  -43.113 1.00 13.53  ? 559 PHE A1 CE1 1 
ATOM 4144 C CE2 . PHE A 1 559 ? 103.117 38.086  -44.811 1.00 13.64  ? 559 PHE A1 CE2 1 
ATOM 4145 C CZ  . PHE A 1 559 ? 102.945 36.990  -43.987 1.00 13.73  ? 559 PHE A1 CZ  1 
ATOM 4146 N N   . ASN A 1 560 ? 96.780  41.170  -43.938 1.00 10.16  ? 560 ASN A1 N   1 
ATOM 4147 C CA  . ASN A 1 560 ? 95.786  42.150  -43.541 1.00 10.90  ? 560 ASN A1 CA  1 
ATOM 4148 C C   . ASN A 1 560 ? 94.870  41.628  -42.451 1.00 11.97  ? 560 ASN A1 C   1 
ATOM 4149 O O   . ASN A 1 560 ? 94.142  42.417  -41.843 1.00 16.42  ? 560 ASN A1 O   1 
ATOM 4150 C CB  . ASN A 1 560 ? 94.923  42.563  -44.731 1.00 11.10  ? 560 ASN A1 CB  1 
ATOM 4151 C CG  . ASN A 1 560 ? 95.729  42.976  -45.933 1.00 13.09  ? 560 ASN A1 CG  1 
ATOM 4152 O OD1 . ASN A 1 560 ? 95.345  42.704  -47.063 1.00 16.31  ? 560 ASN A1 OD1 1 
ATOM 4153 N ND2 . ASN A 1 560 ? 96.844  43.651  -45.702 1.00 13.51  ? 560 ASN A1 ND2 1 
ATOM 4154 N N   . TYR A 1 561 ? 94.892  40.325  -42.191 1.00 10.82  ? 561 TYR A1 N   1 
ATOM 4155 C CA  . TYR A 1 561 ? 93.944  39.679  -41.303 1.00 8.57   ? 561 TYR A1 CA  1 
ATOM 4156 C C   . TYR A 1 561 ? 94.587  39.109  -40.051 1.00 9.10   ? 561 TYR A1 C   1 
ATOM 4157 O O   . TYR A 1 561 ? 93.922  38.384  -39.309 1.00 9.97   ? 561 TYR A1 O   1 
ATOM 4158 C CB  . TYR A 1 561 ? 93.211  38.576  -42.063 1.00 6.49   ? 561 TYR A1 CB  1 
ATOM 4159 C CG  . TYR A 1 561 ? 92.586  39.068  -43.343 1.00 5.67   ? 561 TYR A1 CG  1 
ATOM 4160 C CD1 . TYR A 1 561 ? 91.548  39.985  -43.316 1.00 5.98   ? 561 TYR A1 CD1 1 
ATOM 4161 C CD2 . TYR A 1 561 ? 93.036  38.629  -44.571 1.00 5.65   ? 561 TYR A1 CD2 1 
ATOM 4162 C CE1 . TYR A 1 561 ? 90.974  40.442  -44.480 1.00 6.59   ? 561 TYR A1 CE1 1 
ATOM 4163 C CE2 . TYR A 1 561 ? 92.463  39.080  -45.740 1.00 5.71   ? 561 TYR A1 CE2 1 
ATOM 4164 C CZ  . TYR A 1 561 ? 91.440  39.987  -45.687 1.00 6.64   ? 561 TYR A1 CZ  1 
ATOM 4165 O OH  . TYR A 1 561 ? 90.869  40.440  -46.848 1.00 9.15   ? 561 TYR A1 OH  1 
ATOM 4166 N N   . VAL A 1 562 ? 95.859  39.401  -39.803 1.00 8.43   ? 562 VAL A1 N   1 
ATOM 4167 C CA  . VAL A 1 562 ? 96.568  38.981  -38.598 1.00 9.25   ? 562 VAL A1 CA  1 
ATOM 4168 C C   . VAL A 1 562 ? 97.297  40.206  -38.059 1.00 9.83   ? 562 VAL A1 C   1 
ATOM 4169 O O   . VAL A 1 562 ? 97.542  41.146  -38.827 1.00 13.33  ? 562 VAL A1 O   1 
ATOM 4170 C CB  . VAL A 1 562 ? 97.538  37.826  -38.889 1.00 8.40   ? 562 VAL A1 CB  1 
ATOM 4171 C CG1 . VAL A 1 562 ? 96.789  36.545  -39.130 1.00 9.08   ? 562 VAL A1 CG1 1 
ATOM 4172 C CG2 . VAL A 1 562 ? 98.393  38.154  -40.079 1.00 8.27   ? 562 VAL A1 CG2 1 
ATOM 4173 N N   . PRO A 1 563 ? 97.644  40.269  -36.773 1.00 7.92   ? 563 PRO A1 N   1 
ATOM 4174 C CA  . PRO A 1 563 ? 98.457  41.388  -36.289 1.00 6.94   ? 563 PRO A1 CA  1 
ATOM 4175 C C   . PRO A 1 563 ? 99.891  41.259  -36.772 1.00 7.49   ? 563 PRO A1 C   1 
ATOM 4176 O O   . PRO A 1 563 ? 100.308 40.239  -37.316 1.00 8.06   ? 563 PRO A1 O   1 
ATOM 4177 C CB  . PRO A 1 563 ? 98.370  41.266  -34.768 1.00 5.85   ? 563 PRO A1 CB  1 
ATOM 4178 C CG  . PRO A 1 563 ? 97.246  40.378  -34.515 1.00 5.30   ? 563 PRO A1 CG  1 
ATOM 4179 C CD  . PRO A 1 563 ? 97.193  39.436  -35.651 1.00 6.09   ? 563 PRO A1 CD  1 
ATOM 4180 N N   . SER A 1 564 ? 100.660 42.322  -36.572 1.00 6.07   ? 564 SER A1 N   1 
ATOM 4181 C CA  . SER A 1 564 ? 102.021 42.303  -37.098 1.00 5.69   ? 564 SER A1 CA  1 
ATOM 4182 C C   . SER A 1 564 ? 102.953 42.900  -36.049 1.00 7.73   ? 564 SER A1 C   1 
ATOM 4183 O O   . SER A 1 564 ? 103.187 44.109  -36.043 1.00 9.38   ? 564 SER A1 O   1 
ATOM 4184 C CB  . SER A 1 564 ? 102.113 43.076  -38.401 1.00 4.13   ? 564 SER A1 CB  1 
ATOM 4185 O OG  . SER A 1 564 ? 101.959 44.460  -38.147 1.00 3.64   ? 564 SER A1 OG  1 
ATOM 4186 N N   . ASN A 1 565 ? 103.416 42.049  -35.127 1.00 10.03  ? 565 ASN A1 N   1 
ATOM 4187 C CA  . ASN A 1 565 ? 104.669 42.197  -34.383 1.00 11.55  ? 565 ASN A1 CA  1 
ATOM 4188 C C   . ASN A 1 565 ? 104.682 43.332  -33.358 1.00 12.11  ? 565 ASN A1 C   1 
ATOM 4189 O O   . ASN A 1 565 ? 105.522 43.341  -32.455 1.00 14.30  ? 565 ASN A1 O   1 
ATOM 4190 C CB  . ASN A 1 565 ? 105.814 42.377  -35.389 1.00 13.24  ? 565 ASN A1 CB  1 
ATOM 4191 C CG  . ASN A 1 565 ? 107.179 42.220  -34.769 1.00 14.58  ? 565 ASN A1 CG  1 
ATOM 4192 O OD1 . ASN A 1 565 ? 107.897 43.197  -34.587 1.00 14.53  ? 565 ASN A1 OD1 1 
ATOM 4193 N ND2 . ASN A 1 565 ? 107.549 40.990  -34.446 1.00 15.05  ? 565 ASN A1 ND2 1 
ATOM 4194 N N   . ILE A 1 566 ? 103.717 44.246  -33.428 1.00 9.88   ? 566 ILE A1 N   1 
ATOM 4195 C CA  . ILE A 1 566 ? 103.614 45.390  -32.533 1.00 7.97   ? 566 ILE A1 CA  1 
ATOM 4196 C C   . ILE A 1 566 ? 102.191 45.344  -32.005 1.00 9.39   ? 566 ILE A1 C   1 
ATOM 4197 O O   . ILE A 1 566 ? 101.900 45.789  -30.891 1.00 12.17  ? 566 ILE A1 O   1 
ATOM 4198 C CB  . ILE A 1 566 ? 103.902 46.718  -33.262 1.00 6.76   ? 566 ILE A1 CB  1 
ATOM 4199 C CG1 . ILE A 1 566 ? 105.244 46.682  -33.978 1.00 8.01   ? 566 ILE A1 CG1 1 
ATOM 4200 C CG2 . ILE A 1 566 ? 103.922 47.891  -32.298 1.00 2.36   ? 566 ILE A1 CG2 1 
ATOM 4201 C CD1 . ILE A 1 566 ? 106.401 46.495  -33.059 1.00 10.36  ? 566 ILE A1 CD1 1 
ATOM 4202 N N   . GLY A 1 567 ? 101.308 44.743  -32.791 1.00 9.31   ? 567 GLY A1 N   1 
ATOM 4203 C CA  . GLY A 1 567 ? 99.893  44.759  -32.514 1.00 8.33   ? 567 GLY A1 CA  1 
ATOM 4204 C C   . GLY A 1 567 ? 99.171  45.623  -33.523 1.00 8.65   ? 567 GLY A1 C   1 
ATOM 4205 O O   . GLY A 1 567 ? 98.049  46.071  -33.286 1.00 11.08  ? 567 GLY A1 O   1 
ATOM 4206 N N   . GLY A 1 568 ? 99.814  45.858  -34.659 1.00 8.02   ? 568 GLY A1 N   1 
ATOM 4207 C CA  . GLY A 1 568 ? 99.238  46.703  -35.679 1.00 8.85   ? 568 GLY A1 CA  1 
ATOM 4208 C C   . GLY A 1 568 ? 98.191  45.985  -36.489 1.00 9.24   ? 568 GLY A1 C   1 
ATOM 4209 O O   . GLY A 1 568 ? 98.505  45.098  -37.282 1.00 9.39   ? 568 GLY A1 O   1 
ATOM 4210 N N   . MET A 1 569 ? 96.939  46.350  -36.280 1.00 9.15   ? 569 MET A1 N   1 
ATOM 4211 C CA  . MET A 1 569 ? 95.837  45.743  -36.999 1.00 9.47   ? 569 MET A1 CA  1 
ATOM 4212 C C   . MET A 1 569 ? 95.341  46.684  -38.082 1.00 10.00  ? 569 MET A1 C   1 
ATOM 4213 O O   . MET A 1 569 ? 95.605  47.883  -38.066 1.00 12.07  ? 569 MET A1 O   1 
ATOM 4214 C CB  . MET A 1 569 ? 94.699  45.401  -36.044 1.00 8.18   ? 569 MET A1 CB  1 
ATOM 4215 C CG  . MET A 1 569 ? 94.847  44.069  -35.351 1.00 8.19   ? 569 MET A1 CG  1 
ATOM 4216 S SD  . MET A 1 569 ? 94.835  42.679  -36.490 1.00 7.33   ? 569 MET A1 SD  1 
ATOM 4217 C CE  . MET A 1 569 ? 93.203  42.808  -37.187 1.00 8.57   ? 569 MET A1 CE  1 
ATOM 4218 N N   . LYS A 1 570 ? 94.625  46.113  -39.041 1.00 9.49   ? 570 LYS A1 N   1 
ATOM 4219 C CA  . LYS A 1 570 ? 93.945  46.887  -40.060 1.00 9.19   ? 570 LYS A1 CA  1 
ATOM 4220 C C   . LYS A 1 570 ? 92.781  46.065  -40.580 1.00 8.99   ? 570 LYS A1 C   1 
ATOM 4221 O O   . LYS A 1 570 ? 92.754  44.841  -40.448 1.00 10.72  ? 570 LYS A1 O   1 
ATOM 4222 C CB  . LYS A 1 570 ? 94.887  47.286  -41.197 1.00 9.59   ? 570 LYS A1 CB  1 
ATOM 4223 C CG  . LYS A 1 570 ? 95.165  46.199  -42.197 1.00 11.50  ? 570 LYS A1 CG  1 
ATOM 4224 C CD  . LYS A 1 570 ? 95.745  46.773  -43.466 1.00 14.92  ? 570 LYS A1 CD  1 
ATOM 4225 C CE  . LYS A 1 570 ? 97.220  47.022  -43.323 1.00 16.93  ? 570 LYS A1 CE  1 
ATOM 4226 N NZ  . LYS A 1 570 ? 97.995  45.760  -43.353 1.00 20.94  ? 570 LYS A1 NZ  1 
ATOM 4227 N N   . ILE A 1 571 ? 91.787  46.756  -41.128 1.00 8.26   ? 571 ILE A1 N   1 
ATOM 4228 C CA  . ILE A 1 571 ? 90.663  46.113  -41.792 1.00 7.26   ? 571 ILE A1 CA  1 
ATOM 4229 C C   . ILE A 1 571 ? 90.577  46.675  -43.197 1.00 7.67   ? 571 ILE A1 C   1 
ATOM 4230 O O   . ILE A 1 571 ? 90.144  47.817  -43.385 1.00 9.33   ? 571 ILE A1 O   1 
ATOM 4231 C CB  . ILE A 1 571 ? 89.336  46.322  -41.052 1.00 6.58   ? 571 ILE A1 CB  1 
ATOM 4232 C CG1 . ILE A 1 571 ? 89.479  46.004  -39.566 1.00 5.67   ? 571 ILE A1 CG1 1 
ATOM 4233 C CG2 . ILE A 1 571 ? 88.282  45.453  -41.683 1.00 5.16   ? 571 ILE A1 CG2 1 
ATOM 4234 C CD1 . ILE A 1 571 ? 88.179  45.845  -38.837 1.00 5.46   ? 571 ILE A1 CD1 1 
ATOM 4235 N N   . VAL A 1 572 ? 90.984  45.886  -44.175 1.00 9.09   ? 572 VAL A1 N   1 
ATOM 4236 C CA  . VAL A 1 572 ? 90.909  46.298  -45.557 1.00 7.29   ? 572 VAL A1 CA  1 
ATOM 4237 C C   . VAL A 1 572 ? 89.493  46.070  -46.053 1.00 8.44   ? 572 VAL A1 C   1 
ATOM 4238 O O   . VAL A 1 572 ? 88.750  45.232  -45.539 1.00 9.76   ? 572 VAL A1 O   1 
ATOM 4239 C CB  . VAL A 1 572 ? 91.923  45.554  -46.437 1.00 5.81   ? 572 VAL A1 CB  1 
ATOM 4240 C CG1 . VAL A 1 572 ? 93.301  46.066  -46.163 1.00 8.02   ? 572 VAL A1 CG1 1 
ATOM 4241 C CG2 . VAL A 1 572 ? 91.840  44.075  -46.182 1.00 5.80   ? 572 VAL A1 CG2 1 
ATOM 4242 N N   . TYR A 1 573 ? 89.118  46.825  -47.077 1.00 8.19   ? 573 TYR A1 N   1 
ATOM 4243 C CA  . TYR A 1 573 ? 87.767  46.770  -47.590 1.00 8.32   ? 573 TYR A1 CA  1 
ATOM 4244 C C   . TYR A 1 573 ? 87.538  45.498  -48.394 1.00 8.73   ? 573 TYR A1 C   1 
ATOM 4245 O O   . TYR A 1 573 ? 88.451  44.939  -49.004 1.00 9.78   ? 573 TYR A1 O   1 
ATOM 4246 C CB  . TYR A 1 573 ? 87.475  47.997  -48.444 1.00 10.04  ? 573 TYR A1 CB  1 
ATOM 4247 C CG  . TYR A 1 573 ? 87.899  47.893  -49.889 1.00 12.26  ? 573 TYR A1 CG  1 
ATOM 4248 C CD1 . TYR A 1 573 ? 89.238  47.898  -50.244 1.00 13.53  ? 573 TYR A1 CD1 1 
ATOM 4249 C CD2 . TYR A 1 573 ? 86.955  47.821  -50.898 1.00 13.71  ? 573 TYR A1 CD2 1 
ATOM 4250 C CE1 . TYR A 1 573 ? 89.620  47.813  -51.562 1.00 15.52  ? 573 TYR A1 CE1 1 
ATOM 4251 C CE2 . TYR A 1 573 ? 87.325  47.740  -52.214 1.00 16.00  ? 573 TYR A1 CE2 1 
ATOM 4252 C CZ  . TYR A 1 573 ? 88.655  47.735  -52.541 1.00 18.08  ? 573 TYR A1 CZ  1 
ATOM 4253 O OH  . TYR A 1 573 ? 89.019  47.650  -53.862 1.00 24.12  ? 573 TYR A1 OH  1 
ATOM 4254 N N   . GLU A 1 574 ? 86.295  45.025  -48.365 1.00 9.21   ? 574 GLU A1 N   1 
ATOM 4255 C CA  . GLU A 1 574 ? 85.884  43.844  -49.102 1.00 10.11  ? 574 GLU A1 CA  1 
ATOM 4256 C C   . GLU A 1 574 ? 84.657  44.172  -49.933 1.00 10.68  ? 574 GLU A1 C   1 
ATOM 4257 O O   . GLU A 1 574 ? 83.865  45.044  -49.569 1.00 12.37  ? 574 GLU A1 O   1 
ATOM 4258 C CB  . GLU A 1 574 ? 85.572  42.667  -48.174 1.00 10.75  ? 574 GLU A1 CB  1 
ATOM 4259 C CG  . GLU A 1 574 ? 86.451  42.563  -46.942 1.00 12.79  ? 574 GLU A1 CG  1 
ATOM 4260 C CD  . GLU A 1 574 ? 87.762  41.845  -47.201 1.00 15.00  ? 574 GLU A1 CD  1 
ATOM 4261 O OE1 . GLU A 1 574 ? 87.987  41.390  -48.341 1.00 17.21  ? 574 GLU A1 OE1 1 
ATOM 4262 O OE2 . GLU A 1 574 ? 88.572  41.733  -46.258 1.00 16.10  ? 574 GLU A1 OE2 1 
ATOM 4263 N N   . LYS A 1 575 ? 84.517  43.482  -51.059 1.00 10.01  ? 575 LYS A1 N   1 
ATOM 4264 C CA  . LYS A 1 575 ? 83.338  43.638  -51.893 1.00 9.31   ? 575 LYS A1 CA  1 
ATOM 4265 C C   . LYS A 1 575 ? 82.154  42.935  -51.254 1.00 9.37   ? 575 LYS A1 C   1 
ATOM 4266 O O   . LYS A 1 575 ? 82.312  42.079  -50.387 1.00 9.99   ? 575 LYS A1 O   1 
ATOM 4267 C CB  . LYS A 1 575 ? 83.594  43.077  -53.285 1.00 9.71   ? 575 LYS A1 CB  1 
ATOM 4268 C CG  . LYS A 1 575 ? 84.795  43.681  -53.971 1.00 12.77  ? 575 LYS A1 CG  1 
ATOM 4269 C CD  . LYS A 1 575 ? 84.671  45.185  -54.047 1.00 17.71  ? 575 LYS A1 CD  1 
ATOM 4270 C CE  . LYS A 1 575 ? 85.786  45.767  -54.870 1.00 22.70  ? 575 LYS A1 CE  1 
ATOM 4271 N NZ  . LYS A 1 575 ? 85.583  45.481  -56.313 1.00 28.93  ? 575 LYS A1 NZ  1 
ATOM 4272 N N   . SER A 1 576 ? 80.953  43.306  -51.687 1.00 7.99   ? 576 SER A1 N   1 
ATOM 4273 C CA  . SER A 1 576 ? 79.743  42.863  -51.019 1.00 7.01   ? 576 SER A1 CA  1 
ATOM 4274 C C   . SER A 1 576 ? 78.752  42.149  -51.917 1.00 6.63   ? 576 SER A1 C   1 
ATOM 4275 O O   . SER A 1 576 ? 77.765  41.612  -51.412 1.00 9.63   ? 576 SER A1 O   1 
ATOM 4276 C CB  . SER A 1 576 ? 79.043  44.046  -50.359 1.00 8.33   ? 576 SER A1 CB  1 
ATOM 4277 O OG  . SER A 1 576 ? 79.970  44.827  -49.633 1.00 9.73   ? 576 SER A1 OG  1 
ATOM 4278 N N   . GLN A 1 577 ? 78.977  42.125  -53.223 1.00 4.59   ? 577 GLN A1 N   1 
ATOM 4279 C CA  . GLN A 1 577 ? 78.023  41.627  -54.204 1.00 4.45   ? 577 GLN A1 CA  1 
ATOM 4280 C C   . GLN A 1 577 ? 78.717  40.663  -55.145 1.00 4.99   ? 577 GLN A1 C   1 
ATOM 4281 O O   . GLN A 1 577 ? 78.719  40.829  -56.364 1.00 3.86   ? 577 GLN A1 O   1 
ATOM 4282 C CB  . GLN A 1 577 ? 77.367  42.789  -54.941 1.00 5.14   ? 577 GLN A1 CB  1 
ATOM 4283 C CG  . GLN A 1 577 ? 76.419  43.586  -54.060 1.00 8.84   ? 577 GLN A1 CG  1 
ATOM 4284 C CD  . GLN A 1 577 ? 75.456  44.435  -54.837 1.00 10.22  ? 577 GLN A1 CD  1 
ATOM 4285 O OE1 . GLN A 1 577 ? 75.727  44.828  -55.964 1.00 13.04  ? 577 GLN A1 OE1 1 
ATOM 4286 N NE2 . GLN A 1 577 ? 74.318  44.730  -54.235 1.00 10.70  ? 577 GLN A1 NE2 1 
ATOM 4287 N N   . LEU A 1 578 ? 79.363  39.655  -54.553 1.00 6.24   ? 578 LEU A1 N   1 
ATOM 4288 C CA  . LEU A 1 578 ? 80.331  38.828  -55.267 1.00 5.18   ? 578 LEU A1 CA  1 
ATOM 4289 C C   . LEU A 1 578 ? 79.671  37.944  -56.320 1.00 4.38   ? 578 LEU A1 C   1 
ATOM 4290 O O   . LEU A 1 578 ? 80.190  37.800  -57.431 1.00 5.59   ? 578 LEU A1 O   1 
ATOM 4291 C CB  . LEU A 1 578 ? 81.105  37.968  -54.269 1.00 5.89   ? 578 LEU A1 CB  1 
ATOM 4292 C CG  . LEU A 1 578 ? 82.362  38.486  -53.567 1.00 5.73   ? 578 LEU A1 CG  1 
ATOM 4293 C CD1 . LEU A 1 578 ? 83.411  38.899  -54.565 1.00 5.90   ? 578 LEU A1 CD1 1 
ATOM 4294 C CD2 . LEU A 1 578 ? 82.083  39.606  -52.613 1.00 5.98   ? 578 LEU A1 CD2 1 
ATOM 4295 N N   . ALA A 1 579 ? 78.543  37.349  -55.996 1.00 3.56   ? 579 ALA A1 N   1 
ATOM 4296 C CA  . ALA A 1 579 ? 77.858  36.455  -56.910 1.00 2.98   ? 579 ALA A1 CA  1 
ATOM 4297 C C   . ALA A 1 579 ? 77.100  37.240  -57.974 1.00 3.67   ? 579 ALA A1 C   1 
ATOM 4298 O O   . ALA A 1 579 ? 76.641  38.350  -57.720 1.00 5.32   ? 579 ALA A1 O   1 
ATOM 4299 C CB  . ALA A 1 579 ? 76.879  35.576  -56.151 1.00 2.00   ? 579 ALA A1 CB  1 
ATOM 4300 N N   . PRO A 1 580 ? 76.964  36.698  -59.175 1.00 3.51   ? 580 PRO A1 N   1 
ATOM 4301 C CA  . PRO A 1 580 ? 76.099  37.327  -60.170 1.00 3.95   ? 580 PRO A1 CA  1 
ATOM 4302 C C   . PRO A 1 580 ? 74.681  36.781  -60.113 1.00 5.18   ? 580 PRO A1 C   1 
ATOM 4303 O O   . PRO A 1 580 ? 74.431  35.660  -59.671 1.00 6.47   ? 580 PRO A1 O   1 
ATOM 4304 C CB  . PRO A 1 580 ? 76.774  36.955  -61.492 1.00 3.01   ? 580 PRO A1 CB  1 
ATOM 4305 C CG  . PRO A 1 580 ? 77.391  35.658  -61.215 1.00 2.11   ? 580 PRO A1 CG  1 
ATOM 4306 C CD  . PRO A 1 580 ? 77.819  35.664  -59.780 1.00 2.00   ? 580 PRO A1 CD  1 
ATOM 4307 N N   . ARG A 1 581 ? 73.745  37.612  -60.558 1.00 4.91   ? 581 ARG A1 N   1 
ATOM 4308 C CA  . ARG A 1 581 ? 72.384  37.172  -60.809 1.00 5.97   ? 581 ARG A1 CA  1 
ATOM 4309 C C   . ARG A 1 581 ? 71.965  37.711  -62.161 1.00 6.23   ? 581 ARG A1 C   1 
ATOM 4310 O O   . ARG A 1 581 ? 72.548  38.669  -62.669 1.00 8.62   ? 581 ARG A1 O   1 
ATOM 4311 C CB  . ARG A 1 581 ? 71.400  37.636  -59.735 1.00 5.67   ? 581 ARG A1 CB  1 
ATOM 4312 C CG  . ARG A 1 581 ? 71.171  39.119  -59.708 1.00 6.19   ? 581 ARG A1 CG  1 
ATOM 4313 C CD  . ARG A 1 581 ? 70.182  39.501  -58.638 1.00 4.45   ? 581 ARG A1 CD  1 
ATOM 4314 N NE  . ARG A 1 581 ? 70.583  40.753  -58.015 1.00 4.94   ? 581 ARG A1 NE  1 
ATOM 4315 C CZ  . ARG A 1 581 ? 70.098  41.941  -58.341 1.00 6.28   ? 581 ARG A1 CZ  1 
ATOM 4316 N NH1 . ARG A 1 581 ? 69.171  42.045  -59.271 1.00 6.57   ? 581 ARG A1 NH1 1 
ATOM 4317 N NH2 . ARG A 1 581 ? 70.537  43.023  -57.723 1.00 6.94   ? 581 ARG A1 NH2 1 
ATOM 4318 N N   . LYS A 1 582 ? 70.964  37.083  -62.757 1.00 6.29   ? 582 LYS A1 N   1 
ATOM 4319 C CA  . LYS A 1 582 ? 70.492  37.554  -64.046 1.00 5.74   ? 582 LYS A1 CA  1 
ATOM 4320 C C   . LYS A 1 582 ? 69.431  38.623  -63.843 1.00 5.46   ? 582 LYS A1 C   1 
ATOM 4321 O O   . LYS A 1 582 ? 68.528  38.472  -63.017 1.00 5.03   ? 582 LYS A1 O   1 
ATOM 4322 C CB  . LYS A 1 582 ? 69.957  36.402  -64.895 1.00 5.91   ? 582 LYS A1 CB  1 
ATOM 4323 C CG  . LYS A 1 582 ? 69.031  35.455  -64.190 1.00 4.92   ? 582 LYS A1 CG  1 
ATOM 4324 C CD  . LYS A 1 582 ? 68.517  34.419  -65.153 1.00 5.54   ? 582 LYS A1 CD  1 
ATOM 4325 C CE  . LYS A 1 582 ? 67.220  33.820  -64.661 1.00 6.93   ? 582 LYS A1 CE  1 
ATOM 4326 N NZ  . LYS A 1 582 ? 66.163  34.854  -64.514 1.00 10.90  ? 582 LYS A1 NZ  1 
ATOM 4327 N N   . LEU A 1 583 ? 69.569  39.717  -64.581 1.00 6.99   ? 583 LEU A1 N   1 
ATOM 4328 C CA  . LEU A 1 583 ? 68.618  40.814  -64.486 1.00 7.17   ? 583 LEU A1 CA  1 
ATOM 4329 C C   . LEU A 1 583 ? 67.325  40.468  -65.202 1.00 9.38   ? 583 LEU A1 C   1 
ATOM 4330 O O   . LEU A 1 583 ? 66.258  40.995  -64.876 1.00 13.03  ? 583 LEU A1 O   1 
ATOM 4331 C CB  . LEU A 1 583 ? 69.240  42.068  -65.083 1.00 5.04   ? 583 LEU A1 CB  1 
ATOM 4332 C CG  . LEU A 1 583 ? 68.538  43.402  -64.953 1.00 3.90   ? 583 LEU A1 CG  1 
ATOM 4333 C CD1 . LEU A 1 583 ? 68.620  43.901  -63.533 1.00 2.49   ? 583 LEU A1 CD1 1 
ATOM 4334 C CD2 . LEU A 1 583 ? 69.221  44.332  -65.885 1.00 3.77   ? 583 LEU A1 CD2 1 
ATOM 4335 N N   . TYR A 1 584 ? 67.400  39.574  -66.171 1.00 9.20   ? 584 TYR A1 N   1 
ATOM 4336 C CA  . TYR A 1 584 ? 66.276  39.316  -67.042 1.00 8.40   ? 584 TYR A1 CA  1 
ATOM 4337 C C   . TYR A 1 584 ? 66.284  37.854  -67.448 1.00 9.16   ? 584 TYR A1 C   1 
ATOM 4338 O O   . TYR A 1 584 ? 65.442  37.076  -67.006 1.00 8.54   ? 584 TYR A1 O   1 
ATOM 4339 C CB  . TYR A 1 584 ? 66.355  40.234  -68.257 1.00 5.94   ? 584 TYR A1 CB  1 
ATOM 4340 C CG  . TYR A 1 584 ? 65.096  40.358  -69.066 1.00 4.58   ? 584 TYR A1 CG  1 
ATOM 4341 C CD1 . TYR A 1 584 ? 65.027  39.855  -70.351 1.00 4.14   ? 584 TYR A1 CD1 1 
ATOM 4342 C CD2 . TYR A 1 584 ? 63.984  40.984  -68.545 1.00 3.65   ? 584 TYR A1 CD2 1 
ATOM 4343 C CE1 . TYR A 1 584 ? 63.883  39.975  -71.096 1.00 3.16   ? 584 TYR A1 CE1 1 
ATOM 4344 C CE2 . TYR A 1 584 ? 62.836  41.107  -69.281 1.00 2.88   ? 584 TYR A1 CE2 1 
ATOM 4345 C CZ  . TYR A 1 584 ? 62.790  40.599  -70.553 1.00 2.75   ? 584 TYR A1 CZ  1 
ATOM 4346 O OH  . TYR A 1 584 ? 61.636  40.722  -71.287 1.00 4.40   ? 584 TYR A1 OH  1 
ATOM 4347 O OXT . TYR A 1 584 ? 67.150  37.414  -68.201 1.00 12.34  ? 584 TYR A1 OXT 1 
ATOM 4348 N N   . ASP B 2 1   ? 103.275 72.595  -67.483 1.00 43.27  ? 1   ASP L2 N   1 
ATOM 4349 C CA  . ASP B 2 1   ? 104.133 73.768  -67.407 1.00 43.29  ? 1   ASP L2 CA  1 
ATOM 4350 C C   . ASP B 2 1   ? 104.072 74.560  -68.707 1.00 42.54  ? 1   ASP L2 C   1 
ATOM 4351 O O   . ASP B 2 1   ? 104.621 74.144  -69.725 1.00 43.61  ? 1   ASP L2 O   1 
ATOM 4352 C CB  . ASP B 2 1   ? 105.571 73.359  -67.101 1.00 44.81  ? 1   ASP L2 CB  1 
ATOM 4353 C CG  . ASP B 2 1   ? 106.346 74.445  -66.388 1.00 45.58  ? 1   ASP L2 CG  1 
ATOM 4354 O OD1 . ASP B 2 1   ? 106.481 75.549  -66.950 1.00 47.92  ? 1   ASP L2 OD1 1 
ATOM 4355 O OD2 . ASP B 2 1   ? 106.831 74.193  -65.269 1.00 48.71  ? 1   ASP L2 OD2 1 
ATOM 4356 N N   . ILE B 2 2   ? 103.392 75.700  -68.664 1.00 39.61  ? 2   ILE L2 N   1 
ATOM 4357 C CA  . ILE B 2 2   ? 103.267 76.585  -69.810 1.00 36.85  ? 2   ILE L2 CA  1 
ATOM 4358 C C   . ILE B 2 2   ? 104.497 77.468  -69.876 1.00 36.81  ? 2   ILE L2 C   1 
ATOM 4359 O O   . ILE B 2 2   ? 104.820 78.179  -68.924 1.00 34.90  ? 2   ILE L2 O   1 
ATOM 4360 C CB  . ILE B 2 2   ? 101.994 77.446  -69.728 1.00 36.55  ? 2   ILE L2 CB  1 
ATOM 4361 C CG1 . ILE B 2 2   ? 100.767 76.555  -69.648 1.00 36.29  ? 2   ILE L2 CG1 1 
ATOM 4362 C CG2 . ILE B 2 2   ? 101.897 78.359  -70.917 1.00 35.48  ? 2   ILE L2 CG2 1 
ATOM 4363 C CD1 . ILE B 2 2   ? 99.494  77.310  -69.549 1.00 34.99  ? 2   ILE L2 CD1 1 
ATOM 4364 N N   . VAL B 2 3   ? 105.184 77.434  -71.008 1.00 35.79  ? 3   VAL L2 N   1 
ATOM 4365 C CA  . VAL B 2 3   ? 106.323 78.312  -71.214 1.00 34.27  ? 3   VAL L2 CA  1 
ATOM 4366 C C   . VAL B 2 3   ? 105.815 79.593  -71.861 1.00 33.76  ? 3   VAL L2 C   1 
ATOM 4367 O O   . VAL B 2 3   ? 104.856 79.592  -72.641 1.00 33.99  ? 3   VAL L2 O   1 
ATOM 4368 C CB  . VAL B 2 3   ? 107.453 77.626  -72.024 1.00 34.64  ? 3   VAL L2 CB  1 
ATOM 4369 C CG1 . VAL B 2 3   ? 107.166 77.566  -73.513 1.00 35.14  ? 3   VAL L2 CG1 1 
ATOM 4370 C CG2 . VAL B 2 3   ? 108.790 78.290  -71.748 1.00 32.82  ? 3   VAL L2 CG2 1 
ATOM 4371 N N   . MET B 2 4   ? 106.405 80.709  -71.450 1.00 32.32  ? 4   MET L2 N   1 
ATOM 4372 C CA  . MET B 2 4   ? 106.002 82.034  -71.902 1.00 30.72  ? 4   MET L2 CA  1 
ATOM 4373 C C   . MET B 2 4   ? 107.183 82.652  -72.629 1.00 30.57  ? 4   MET L2 C   1 
ATOM 4374 O O   . MET B 2 4   ? 108.307 82.626  -72.118 1.00 28.56  ? 4   MET L2 O   1 
ATOM 4375 C CB  . MET B 2 4   ? 105.568 82.911  -70.732 1.00 30.23  ? 4   MET L2 CB  1 
ATOM 4376 C CG  . MET B 2 4   ? 104.636 82.231  -69.769 1.00 31.43  ? 4   MET L2 CG  1 
ATOM 4377 S SD  . MET B 2 4   ? 103.053 81.904  -70.531 1.00 29.26  ? 4   MET L2 SD  1 
ATOM 4378 C CE  . MET B 2 4   ? 102.592 83.571  -70.927 1.00 26.04  ? 4   MET L2 CE  1 
ATOM 4379 N N   . THR B 2 5   ? 106.939 83.192  -73.818 1.00 30.15  ? 5   THR L2 N   1 
ATOM 4380 C CA  . THR B 2 5   ? 107.981 83.820  -74.617 1.00 31.39  ? 5   THR L2 CA  1 
ATOM 4381 C C   . THR B 2 5   ? 107.590 85.259  -74.909 1.00 31.75  ? 5   THR L2 C   1 
ATOM 4382 O O   . THR B 2 5   ? 106.515 85.512  -75.462 1.00 31.63  ? 5   THR L2 O   1 
ATOM 4383 C CB  . THR B 2 5   ? 108.218 83.053  -75.917 1.00 31.77  ? 5   THR L2 CB  1 
ATOM 4384 O OG1 . THR B 2 5   ? 106.979 82.905  -76.620 1.00 35.82  ? 5   THR L2 OG1 1 
ATOM 4385 C CG2 . THR B 2 5   ? 108.805 81.688  -75.638 1.00 30.37  ? 5   THR L2 CG2 1 
ATOM 4386 N N   . GLN B 2 6   ? 108.451 86.196  -74.532 1.00 31.12  ? 6   GLN L2 N   1 
ATOM 4387 C CA  . GLN B 2 6   ? 108.276 87.583  -74.924 1.00 31.23  ? 6   GLN L2 CA  1 
ATOM 4388 C C   . GLN B 2 6   ? 109.064 87.845  -76.198 1.00 32.49  ? 6   GLN L2 C   1 
ATOM 4389 O O   . GLN B 2 6   ? 110.156 87.303  -76.393 1.00 32.33  ? 6   GLN L2 O   1 
ATOM 4390 C CB  . GLN B 2 6   ? 108.712 88.529  -73.806 1.00 30.77  ? 6   GLN L2 CB  1 
ATOM 4391 C CG  . GLN B 2 6   ? 107.928 88.330  -72.525 1.00 29.45  ? 6   GLN L2 CG  1 
ATOM 4392 C CD  . GLN B 2 6   ? 107.812 89.588  -71.697 1.00 29.75  ? 6   GLN L2 CD  1 
ATOM 4393 O OE1 . GLN B 2 6   ? 108.022 89.566  -70.490 1.00 28.59  ? 6   GLN L2 OE1 1 
ATOM 4394 N NE2 . GLN B 2 6   ? 107.462 90.687  -72.337 1.00 27.06  ? 6   GLN L2 NE2 1 
ATOM 4395 N N   . SER B 2 7   ? 108.496 88.675  -77.072 1.00 34.05  ? 7   SER L2 N   1 
ATOM 4396 C CA  . SER B 2 7   ? 108.990 88.823  -78.434 1.00 35.30  ? 7   SER L2 CA  1 
ATOM 4397 C C   . SER B 2 7   ? 110.307 89.581  -78.530 1.00 35.56  ? 7   SER L2 C   1 
ATOM 4398 O O   . SER B 2 7   ? 110.992 89.465  -79.552 1.00 37.81  ? 7   SER L2 O   1 
ATOM 4399 C CB  . SER B 2 7   ? 107.931 89.517  -79.291 1.00 33.70  ? 7   SER L2 CB  1 
ATOM 4400 O OG  . SER B 2 7   ? 106.777 88.708  -79.424 1.00 35.90  ? 7   SER L2 OG  1 
ATOM 4401 N N   . HIS B 2 8   ? 110.669 90.361  -77.518 1.00 34.39  ? 8   HIS L2 N   1 
ATOM 4402 C CA  . HIS B 2 8   ? 111.910 91.118  -77.515 1.00 33.49  ? 8   HIS L2 CA  1 
ATOM 4403 C C   . HIS B 2 8   ? 112.482 91.110  -76.109 1.00 32.27  ? 8   HIS L2 C   1 
ATOM 4404 O O   . HIS B 2 8   ? 111.732 91.152  -75.132 1.00 30.41  ? 8   HIS L2 O   1 
ATOM 4405 C CB  . HIS B 2 8   ? 111.696 92.571  -77.952 1.00 35.69  ? 8   HIS L2 CB  1 
ATOM 4406 C CG  . HIS B 2 8   ? 111.405 92.744  -79.410 1.00 39.64  ? 8   HIS L2 CG  1 
ATOM 4407 N ND1 . HIS B 2 8   ? 110.199 92.396  -79.978 1.00 42.00  ? 8   HIS L2 ND1 1 
ATOM 4408 C CD2 . HIS B 2 8   ? 112.150 93.274  -80.409 1.00 40.43  ? 8   HIS L2 CD2 1 
ATOM 4409 C CE1 . HIS B 2 8   ? 110.223 92.680  -81.268 1.00 41.93  ? 8   HIS L2 CE1 1 
ATOM 4410 N NE2 . HIS B 2 8   ? 111.395 93.216  -81.554 1.00 42.88  ? 8   HIS L2 NE2 1 
ATOM 4411 N N   . LYS B 2 9   ? 113.806 91.063  -76.004 1.00 31.23  ? 9   LYS L2 N   1 
ATOM 4412 C CA  . LYS B 2 9   ? 114.454 91.317  -74.726 1.00 29.38  ? 9   LYS L2 CA  1 
ATOM 4413 C C   . LYS B 2 9   ? 114.630 92.799  -74.457 1.00 27.63  ? 9   LYS L2 C   1 
ATOM 4414 O O   . LYS B 2 9   ? 114.650 93.208  -73.293 1.00 24.67  ? 9   LYS L2 O   1 
ATOM 4415 C CB  . LYS B 2 9   ? 115.821 90.635  -74.666 1.00 29.55  ? 9   LYS L2 CB  1 
ATOM 4416 C CG  . LYS B 2 9   ? 115.773 89.141  -74.852 1.00 30.45  ? 9   LYS L2 CG  1 
ATOM 4417 C CD  . LYS B 2 9   ? 115.439 88.465  -73.540 1.00 31.74  ? 9   LYS L2 CD  1 
ATOM 4418 C CE  . LYS B 2 9   ? 115.262 86.973  -73.711 1.00 33.77  ? 9   LYS L2 CE  1 
ATOM 4419 N NZ  . LYS B 2 9   ? 114.789 86.340  -72.456 1.00 34.17  ? 9   LYS L2 NZ  1 
ATOM 4420 N N   . PHE B 2 10  ? 114.765 93.607  -75.506 1.00 27.46  ? 10  PHE L2 N   1 
ATOM 4421 C CA  . PHE B 2 10  ? 114.946 95.043  -75.377 1.00 27.99  ? 10  PHE L2 CA  1 
ATOM 4422 C C   . PHE B 2 10  ? 114.116 95.720  -76.453 1.00 27.47  ? 10  PHE L2 C   1 
ATOM 4423 O O   . PHE B 2 10  ? 114.169 95.317  -77.617 1.00 27.57  ? 10  PHE L2 O   1 
ATOM 4424 C CB  . PHE B 2 10  ? 116.420 95.443  -75.524 1.00 27.96  ? 10  PHE L2 CB  1 
ATOM 4425 C CG  . PHE B 2 10  ? 117.359 94.654  -74.662 1.00 27.72  ? 10  PHE L2 CG  1 
ATOM 4426 C CD1 . PHE B 2 10  ? 118.048 93.570  -75.181 1.00 28.39  ? 10  PHE L2 CD1 1 
ATOM 4427 C CD2 . PHE B 2 10  ? 117.556 94.995  -73.338 1.00 27.77  ? 10  PHE L2 CD2 1 
ATOM 4428 C CE1 . PHE B 2 10  ? 118.910 92.837  -74.394 1.00 27.73  ? 10  PHE L2 CE1 1 
ATOM 4429 C CE2 . PHE B 2 10  ? 118.419 94.270  -72.545 1.00 28.63  ? 10  PHE L2 CE2 1 
ATOM 4430 C CZ  . PHE B 2 10  ? 119.096 93.188  -73.072 1.00 27.59  ? 10  PHE L2 CZ  1 
ATOM 4431 N N   . MET B 2 11  ? 113.356 96.737  -76.069 1.00 29.33  ? 11  MET L2 N   1 
ATOM 4432 C CA  . MET B 2 11  ? 112.560 97.504  -77.014 1.00 30.34  ? 11  MET L2 CA  1 
ATOM 4433 C C   . MET B 2 11  ? 112.984 98.960  -76.954 1.00 30.62  ? 11  MET L2 C   1 
ATOM 4434 O O   . MET B 2 11  ? 112.873 99.597  -75.903 1.00 28.51  ? 11  MET L2 O   1 
ATOM 4435 C CB  . MET B 2 11  ? 111.064 97.380  -76.721 1.00 32.16  ? 11  MET L2 CB  1 
ATOM 4436 C CG  . MET B 2 11  ? 110.495 96.012  -77.017 1.00 35.60  ? 11  MET L2 CG  1 
ATOM 4437 S SD  . MET B 2 11  ? 108.833 96.082  -77.697 1.00 38.47  ? 11  MET L2 SD  1 
ATOM 4438 C CE  . MET B 2 11  ? 108.436 94.336  -77.761 1.00 33.86  ? 11  MET L2 CE  1 
ATOM 4439 N N   . SER B 2 12  ? 113.464 99.479  -78.080 1.00 31.50  ? 12  SER L2 N   1 
ATOM 4440 C CA  . SER B 2 12  ? 113.891 100.866 -78.181 1.00 32.78  ? 12  SER L2 CA  1 
ATOM 4441 C C   . SER B 2 12  ? 112.673 101.775 -78.178 1.00 34.04  ? 12  SER L2 C   1 
ATOM 4442 O O   . SER B 2 12  ? 111.766 101.612 -78.999 1.00 36.37  ? 12  SER L2 O   1 
ATOM 4443 C CB  . SER B 2 12  ? 114.702 101.087 -79.453 1.00 31.52  ? 12  SER L2 CB  1 
ATOM 4444 O OG  . SER B 2 12  ? 113.844 101.322 -80.556 1.00 31.53  ? 12  SER L2 OG  1 
ATOM 4445 N N   . THR B 2 13  ? 112.655 102.732 -77.258 1.00 33.46  ? 13  THR L2 N   1 
ATOM 4446 C CA  . THR B 2 13  ? 111.508 103.608 -77.101 1.00 35.45  ? 13  THR L2 CA  1 
ATOM 4447 C C   . THR B 2 13  ? 111.975 105.051 -77.062 1.00 35.28  ? 13  THR L2 C   1 
ATOM 4448 O O   . THR B 2 13  ? 113.065 105.353 -76.572 1.00 34.39  ? 13  THR L2 O   1 
ATOM 4449 C CB  . THR B 2 13  ? 110.732 103.309 -75.817 1.00 37.45  ? 13  THR L2 CB  1 
ATOM 4450 O OG1 . THR B 2 13  ? 111.654 103.125 -74.739 1.00 41.64  ? 13  THR L2 OG1 1 
ATOM 4451 C CG2 . THR B 2 13  ? 109.909 102.066 -75.977 1.00 36.28  ? 13  THR L2 CG2 1 
ATOM 4452 N N   . SER B 2 14  ? 111.138 105.936 -77.576 1.00 35.92  ? 14  SER L2 N   1 
ATOM 4453 C CA  . SER B 2 14  ? 111.307 107.359 -77.376 1.00 37.43  ? 14  SER L2 CA  1 
ATOM 4454 C C   . SER B 2 14  ? 110.294 107.815 -76.338 1.00 37.84  ? 14  SER L2 C   1 
ATOM 4455 O O   . SER B 2 14  ? 109.263 107.175 -76.127 1.00 39.75  ? 14  SER L2 O   1 
ATOM 4456 C CB  . SER B 2 14  ? 111.138 108.126 -78.689 1.00 36.87  ? 14  SER L2 CB  1 
ATOM 4457 O OG  . SER B 2 14  ? 109.791 108.521 -78.880 1.00 39.10  ? 14  SER L2 OG  1 
ATOM 4458 N N   . VAL B 2 15  ? 110.605 108.924 -75.670 1.00 38.05  ? 15  VAL L2 N   1 
ATOM 4459 C CA  . VAL B 2 15  ? 109.669 109.501 -74.716 1.00 38.79  ? 15  VAL L2 CA  1 
ATOM 4460 C C   . VAL B 2 15  ? 108.487 110.089 -75.470 1.00 39.50  ? 15  VAL L2 C   1 
ATOM 4461 O O   . VAL B 2 15  ? 108.655 110.810 -76.462 1.00 38.31  ? 15  VAL L2 O   1 
ATOM 4462 C CB  . VAL B 2 15  ? 110.370 110.561 -73.852 1.00 39.87  ? 15  VAL L2 CB  1 
ATOM 4463 C CG1 . VAL B 2 15  ? 109.503 110.941 -72.664 1.00 39.98  ? 15  VAL L2 CG1 1 
ATOM 4464 C CG2 . VAL B 2 15  ? 111.716 110.041 -73.392 1.00 41.52  ? 15  VAL L2 CG2 1 
ATOM 4465 N N   . GLY B 2 16  ? 107.280 109.761 -75.017 1.00 39.89  ? 16  GLY L2 N   1 
ATOM 4466 C CA  . GLY B 2 16  ? 106.071 110.177 -75.689 1.00 40.63  ? 16  GLY L2 CA  1 
ATOM 4467 C C   . GLY B 2 16  ? 105.587 109.248 -76.778 1.00 41.31  ? 16  GLY L2 C   1 
ATOM 4468 O O   . GLY B 2 16  ? 104.596 109.569 -77.445 1.00 41.96  ? 16  GLY L2 O   1 
ATOM 4469 N N   . ASP B 2 17  ? 106.241 108.110 -76.985 1.00 40.09  ? 17  ASP L2 N   1 
ATOM 4470 C CA  . ASP B 2 17  ? 105.887 107.231 -78.087 1.00 40.37  ? 17  ASP L2 CA  1 
ATOM 4471 C C   . ASP B 2 17  ? 104.815 106.223 -77.670 1.00 39.65  ? 17  ASP L2 C   1 
ATOM 4472 O O   . ASP B 2 17  ? 104.132 106.372 -76.654 1.00 39.55  ? 17  ASP L2 O   1 
ATOM 4473 C CB  . ASP B 2 17  ? 107.121 106.502 -78.609 1.00 43.03  ? 17  ASP L2 CB  1 
ATOM 4474 C CG  . ASP B 2 17  ? 107.164 106.450 -80.120 1.00 45.58  ? 17  ASP L2 CG  1 
ATOM 4475 O OD1 . ASP B 2 17  ? 106.087 106.559 -80.742 1.00 48.40  ? 17  ASP L2 OD1 1 
ATOM 4476 O OD2 . ASP B 2 17  ? 108.267 106.305 -80.686 1.00 45.24  ? 17  ASP L2 OD2 1 
ATOM 4477 N N   . ARG B 2 18  ? 104.656 105.196 -78.501 1.00 38.44  ? 18  ARG L2 N   1 
ATOM 4478 C CA  . ARG B 2 18  ? 103.687 104.128 -78.292 1.00 38.52  ? 18  ARG L2 CA  1 
ATOM 4479 C C   . ARG B 2 18  ? 104.374 102.788 -78.507 1.00 37.37  ? 18  ARG L2 C   1 
ATOM 4480 O O   . ARG B 2 18  ? 104.734 102.447 -79.638 1.00 36.93  ? 18  ARG L2 O   1 
ATOM 4481 C CB  . ARG B 2 18  ? 102.508 104.287 -79.250 1.00 39.35  ? 18  ARG L2 CB  1 
ATOM 4482 C CG  . ARG B 2 18  ? 101.400 103.270 -79.088 1.00 40.17  ? 18  ARG L2 CG  1 
ATOM 4483 C CD  . ARG B 2 18  ? 100.432 103.374 -80.255 1.00 40.95  ? 18  ARG L2 CD  1 
ATOM 4484 N NE  . ARG B 2 18  ? 99.273  102.503 -80.105 1.00 40.36  ? 18  ARG L2 NE  1 
ATOM 4485 C CZ  . ARG B 2 18  ? 98.135  102.877 -79.534 1.00 38.63  ? 18  ARG L2 CZ  1 
ATOM 4486 N NH1 . ARG B 2 18  ? 98.008  104.104 -79.051 1.00 37.36  ? 18  ARG L2 NH1 1 
ATOM 4487 N NH2 . ARG B 2 18  ? 97.125  102.024 -79.437 1.00 37.07  ? 18  ARG L2 NH2 1 
ATOM 4488 N N   . VAL B 2 19  ? 104.542 102.026 -77.429 1.00 35.60  ? 19  VAL L2 N   1 
ATOM 4489 C CA  . VAL B 2 19  ? 105.307 100.785 -77.453 1.00 36.09  ? 19  VAL L2 CA  1 
ATOM 4490 C C   . VAL B 2 19  ? 104.341 99.618  -77.287 1.00 34.68  ? 19  VAL L2 C   1 
ATOM 4491 O O   . VAL B 2 19  ? 103.356 99.713  -76.547 1.00 34.31  ? 19  VAL L2 O   1 
ATOM 4492 C CB  . VAL B 2 19  ? 106.410 100.794 -76.364 1.00 35.98  ? 19  VAL L2 CB  1 
ATOM 4493 C CG1 . VAL B 2 19  ? 105.840 101.082 -74.983 1.00 35.69  ? 19  VAL L2 CG1 1 
ATOM 4494 C CG2 . VAL B 2 19  ? 107.241 99.513  -76.368 1.00 36.08  ? 19  VAL L2 CG2 1 
ATOM 4495 N N   . SER B 2 20  ? 104.589 98.535  -78.021 1.00 34.50  ? 20  SER L2 N   1 
ATOM 4496 C CA  . SER B 2 20  ? 103.764 97.333  -77.968 1.00 35.06  ? 20  SER L2 CA  1 
ATOM 4497 C C   . SER B 2 20  ? 104.637 96.155  -77.548 1.00 35.42  ? 20  SER L2 C   1 
ATOM 4498 O O   . SER B 2 20  ? 105.309 95.540  -78.380 1.00 36.06  ? 20  SER L2 O   1 
ATOM 4499 C CB  . SER B 2 20  ? 103.084 97.078  -79.305 1.00 35.02  ? 20  SER L2 CB  1 
ATOM 4500 O OG  . SER B 2 20  ? 101.942 97.903  -79.441 1.00 35.37  ? 20  SER L2 OG  1 
ATOM 4501 N N   . ILE B 2 21  ? 104.618 95.845  -76.259 1.00 36.01  ? 21  ILE L2 N   1 
ATOM 4502 C CA  . ILE B 2 21  ? 105.326 94.687  -75.727 1.00 36.42  ? 21  ILE L2 CA  1 
ATOM 4503 C C   . ILE B 2 21  ? 104.430 93.465  -75.865 1.00 35.49  ? 21  ILE L2 C   1 
ATOM 4504 O O   . ILE B 2 21  ? 103.263 93.494  -75.462 1.00 35.87  ? 21  ILE L2 O   1 
ATOM 4505 C CB  . ILE B 2 21  ? 105.721 94.928  -74.265 1.00 37.30  ? 21  ILE L2 CB  1 
ATOM 4506 C CG1 . ILE B 2 21  ? 106.302 96.334  -74.118 1.00 38.85  ? 21  ILE L2 CG1 1 
ATOM 4507 C CG2 . ILE B 2 21  ? 106.699 93.873  -73.790 1.00 38.82  ? 21  ILE L2 CG2 1 
ATOM 4508 C CD1 . ILE B 2 21  ? 106.249 96.878  -72.736 1.00 38.81  ? 21  ILE L2 CD1 1 
ATOM 4509 N N   . THR B 2 22  ? 104.969 92.390  -76.426 1.00 35.05  ? 22  THR L2 N   1 
ATOM 4510 C CA  . THR B 2 22  ? 104.198 91.203  -76.767 1.00 37.01  ? 22  THR L2 CA  1 
ATOM 4511 C C   . THR B 2 22  ? 104.707 90.004  -75.979 1.00 37.10  ? 22  THR L2 C   1 
ATOM 4512 O O   . THR B 2 22  ? 105.916 89.770  -75.912 1.00 36.25  ? 22  THR L2 O   1 
ATOM 4513 C CB  . THR B 2 22  ? 104.280 90.934  -78.274 1.00 37.70  ? 22  THR L2 CB  1 
ATOM 4514 O OG1 . THR B 2 22  ? 103.640 92.002  -78.983 1.00 38.18  ? 22  THR L2 OG1 1 
ATOM 4515 C CG2 . THR B 2 22  ? 103.618 89.613  -78.660 1.00 37.89  ? 22  THR L2 CG2 1 
ATOM 4516 N N   . CYS B 2 23  ? 103.782 89.260  -75.370 1.00 37.48  ? 23  CYS L2 N   1 
ATOM 4517 C CA  . CYS B 2 23  ? 104.057 87.974  -74.744 1.00 38.66  ? 23  CYS L2 CA  1 
ATOM 4518 C C   . CYS B 2 23  ? 103.289 86.904  -75.495 1.00 38.92  ? 23  CYS L2 C   1 
ATOM 4519 O O   . CYS B 2 23  ? 102.114 87.093  -75.812 1.00 38.09  ? 23  CYS L2 O   1 
ATOM 4520 C CB  . CYS B 2 23  ? 103.633 87.974  -73.280 1.00 41.13  ? 23  CYS L2 CB  1 
ATOM 4521 S SG  . CYS B 2 23  ? 104.221 86.624  -72.265 1.00 43.54  ? 23  CYS L2 SG  1 
ATOM 4522 N N   . LYS B 2 24  ? 103.944 85.786  -75.777 1.00 39.16  ? 24  LYS L2 N   1 
ATOM 4523 C CA  . LYS B 2 24  ? 103.302 84.679  -76.473 1.00 41.46  ? 24  LYS L2 CA  1 
ATOM 4524 C C   . LYS B 2 24  ? 103.418 83.430  -75.617 1.00 42.95  ? 24  LYS L2 C   1 
ATOM 4525 O O   . LYS B 2 24  ? 104.513 83.088  -75.161 1.00 44.58  ? 24  LYS L2 O   1 
ATOM 4526 C CB  . LYS B 2 24  ? 103.916 84.449  -77.851 1.00 41.75  ? 24  LYS L2 CB  1 
ATOM 4527 C CG  . LYS B 2 24  ? 103.104 83.499  -78.695 1.00 41.69  ? 24  LYS L2 CG  1 
ATOM 4528 C CD  . LYS B 2 24  ? 103.598 83.443  -80.118 1.00 42.54  ? 24  LYS L2 CD  1 
ATOM 4529 C CE  . LYS B 2 24  ? 102.745 82.499  -80.940 1.00 43.40  ? 24  LYS L2 CE  1 
ATOM 4530 N NZ  . LYS B 2 24  ? 101.318 82.924  -80.958 1.00 42.82  ? 24  LYS L2 NZ  1 
ATOM 4531 N N   . ALA B 2 25  ? 102.291 82.760  -75.396 1.00 43.54  ? 25  ALA L2 N   1 
ATOM 4532 C CA  . ALA B 2 25  ? 102.256 81.578  -74.553 1.00 44.45  ? 25  ALA L2 CA  1 
ATOM 4533 C C   . ALA B 2 25  ? 102.247 80.308  -75.389 1.00 44.58  ? 25  ALA L2 C   1 
ATOM 4534 O O   . ALA B 2 25  ? 101.864 80.309  -76.561 1.00 46.44  ? 25  ALA L2 O   1 
ATOM 4535 C CB  . ALA B 2 25  ? 101.025 81.596  -73.653 1.00 44.70  ? 25  ALA L2 CB  1 
ATOM 4536 N N   . SER B 2 26  ? 102.668 79.211  -74.766 1.00 44.77  ? 26  SER L2 N   1 
ATOM 4537 C CA  . SER B 2 26  ? 102.709 77.932  -75.464 1.00 45.09  ? 26  SER L2 CA  1 
ATOM 4538 C C   . SER B 2 26  ? 101.324 77.304  -75.538 1.00 46.32  ? 26  SER L2 C   1 
ATOM 4539 O O   . SER B 2 26  ? 100.893 76.847  -76.601 1.00 46.74  ? 26  SER L2 O   1 
ATOM 4540 C CB  . SER B 2 26  ? 103.690 76.992  -74.771 1.00 43.99  ? 26  SER L2 CB  1 
ATOM 4541 O OG  . SER B 2 26  ? 103.062 76.294  -73.716 1.00 46.39  ? 26  SER L2 OG  1 
ATOM 4542 N N   . GLN B 2 27  ? 100.624 77.260  -74.415 1.00 46.31  ? 27  GLN L2 N   1 
ATOM 4543 C CA  . GLN B 2 27  ? 99.277  76.725  -74.335 1.00 46.62  ? 27  GLN L2 CA  1 
ATOM 4544 C C   . GLN B 2 27  ? 98.261  77.860  -74.311 1.00 46.75  ? 27  GLN L2 C   1 
ATOM 4545 O O   . GLN B 2 27  ? 98.548  78.966  -73.854 1.00 46.59  ? 27  GLN L2 O   1 
ATOM 4546 C CB  . GLN B 2 27  ? 99.134  75.860  -73.087 1.00 45.42  ? 27  GLN L2 CB  1 
ATOM 4547 C CG  . GLN B 2 27  ? 98.102  74.776  -73.198 1.00 46.46  ? 27  GLN L2 CG  1 
ATOM 4548 C CD  . GLN B 2 27  ? 97.735  74.212  -71.855 1.00 46.58  ? 27  GLN L2 CD  1 
ATOM 4549 O OE1 . GLN B 2 27  ? 98.578  74.095  -70.968 1.00 47.76  ? 27  GLN L2 OE1 1 
ATOM 4550 N NE2 . GLN B 2 27  ? 96.466  73.876  -71.685 1.00 45.62  ? 27  GLN L2 NE2 1 
ATOM 4551 N N   . ASP B 2 28  ? 97.063  77.576  -74.812 1.00 45.02  ? 28  ASP L2 N   1 
ATOM 4552 C CA  . ASP B 2 28  ? 96.022  78.592  -74.900 1.00 45.09  ? 28  ASP L2 CA  1 
ATOM 4553 C C   . ASP B 2 28  ? 95.502  78.932  -73.507 1.00 44.10  ? 28  ASP L2 C   1 
ATOM 4554 O O   . ASP B 2 28  ? 94.710  78.181  -72.935 1.00 44.23  ? 28  ASP L2 O   1 
ATOM 4555 C CB  . ASP B 2 28  ? 94.890  78.095  -75.800 1.00 45.11  ? 28  ASP L2 CB  1 
ATOM 4556 C CG  . ASP B 2 28  ? 93.880  79.188  -76.178 1.00 47.19  ? 28  ASP L2 CG  1 
ATOM 4557 O OD1 . ASP B 2 28  ? 93.599  79.314  -77.387 1.00 46.28  ? 28  ASP L2 OD1 1 
ATOM 4558 O OD2 . ASP B 2 28  ? 93.317  79.881  -75.307 1.00 48.14  ? 28  ASP L2 OD2 1 
ATOM 4559 N N   . VAL B 2 29  ? 95.925  80.076  -72.980 1.00 43.34  ? 29  VAL L2 N   1 
ATOM 4560 C CA  . VAL B 2 29  ? 95.379  80.630  -71.751 1.00 41.12  ? 29  VAL L2 CA  1 
ATOM 4561 C C   . VAL B 2 29  ? 94.266  81.583  -72.168 1.00 40.88  ? 29  VAL L2 C   1 
ATOM 4562 O O   . VAL B 2 29  ? 94.341  82.184  -73.242 1.00 39.51  ? 29  VAL L2 O   1 
ATOM 4563 C CB  . VAL B 2 29  ? 96.475  81.313  -70.909 1.00 40.32  ? 29  VAL L2 CB  1 
ATOM 4564 C CG1 . VAL B 2 29  ? 97.615  80.355  -70.703 1.00 37.74  ? 29  VAL L2 CG1 1 
ATOM 4565 C CG2 . VAL B 2 29  ? 97.013  82.547  -71.541 1.00 38.45  ? 29  VAL L2 CG2 1 
ATOM 4566 N N   . ASN B 2 30  ? 93.187  81.650  -71.385 1.00 41.18  ? 30  ASN L2 N   1 
ATOM 4567 C CA  . ASN B 2 30  ? 91.976  82.272  -71.926 1.00 41.29  ? 30  ASN L2 CA  1 
ATOM 4568 C C   . ASN B 2 30  ? 92.103  83.791  -71.958 1.00 40.53  ? 30  ASN L2 C   1 
ATOM 4569 O O   . ASN B 2 30  ? 92.144  84.399  -73.030 1.00 42.07  ? 30  ASN L2 O   1 
ATOM 4570 C CB  . ASN B 2 30  ? 90.739  81.829  -71.134 1.00 43.07  ? 30  ASN L2 CB  1 
ATOM 4571 C CG  . ASN B 2 30  ? 90.971  81.788  -69.642 1.00 43.83  ? 30  ASN L2 CG  1 
ATOM 4572 O OD1 . ASN B 2 30  ? 91.795  81.033  -69.155 1.00 44.29  ? 30  ASN L2 OD1 1 
ATOM 4573 N ND2 . ASN B 2 30  ? 90.229  82.600  -68.907 1.00 45.36  ? 30  ASN L2 ND2 1 
ATOM 4574 N N   . THR B 2 31  ? 92.182  84.419  -70.792 1.00 39.81  ? 31  THR L2 N   1 
ATOM 4575 C CA  . THR B 2 31  ? 92.756  85.752  -70.676 1.00 38.26  ? 31  THR L2 CA  1 
ATOM 4576 C C   . THR B 2 31  ? 93.977  85.675  -69.774 1.00 36.69  ? 31  THR L2 C   1 
ATOM 4577 O O   . THR B 2 31  ? 95.061  86.061  -70.204 1.00 36.89  ? 31  THR L2 O   1 
ATOM 4578 C CB  . THR B 2 31  ? 91.722  86.750  -70.166 1.00 38.91  ? 31  THR L2 CB  1 
ATOM 4579 O OG1 . THR B 2 31  ? 90.998  86.178  -69.075 1.00 41.49  ? 31  THR L2 OG1 1 
ATOM 4580 C CG2 . THR B 2 31  ? 90.758  87.111  -71.265 1.00 41.59  ? 31  THR L2 CG2 1 
ATOM 4581 N N   . ALA B 2 32  ? 93.810  85.230  -68.525 1.00 34.36  ? 32  ALA L2 N   1 
ATOM 4582 C CA  . ALA B 2 32  ? 94.768  84.565  -67.644 1.00 32.96  ? 32  ALA L2 CA  1 
ATOM 4583 C C   . ALA B 2 32  ? 96.214  85.027  -67.728 1.00 32.47  ? 32  ALA L2 C   1 
ATOM 4584 O O   . ALA B 2 32  ? 97.121  84.198  -67.807 1.00 32.18  ? 32  ALA L2 O   1 
ATOM 4585 C CB  . ALA B 2 32  ? 94.715  83.062  -67.892 1.00 32.23  ? 32  ALA L2 CB  1 
ATOM 4586 N N   . LEU B 2 33  ? 96.449  86.335  -67.719 1.00 31.97  ? 33  LEU L2 N   1 
ATOM 4587 C CA  . LEU B 2 33  ? 97.806  86.821  -67.885 1.00 32.80  ? 33  LEU L2 CA  1 
ATOM 4588 C C   . LEU B 2 33  ? 97.986  88.132  -67.144 1.00 31.90  ? 33  LEU L2 C   1 
ATOM 4589 O O   . LEU B 2 33  ? 97.161  89.036  -67.261 1.00 32.85  ? 33  LEU L2 O   1 
ATOM 4590 C CB  . LEU B 2 33  ? 98.150  86.990  -69.361 1.00 34.10  ? 33  LEU L2 CB  1 
ATOM 4591 C CG  . LEU B 2 33  ? 99.636  87.059  -69.668 1.00 33.57  ? 33  LEU L2 CG  1 
ATOM 4592 C CD1 . LEU B 2 33  ? 99.931  86.146  -70.804 1.00 36.24  ? 33  LEU L2 CD1 1 
ATOM 4593 C CD2 . LEU B 2 33  ? 100.033 88.455  -70.037 1.00 33.75  ? 33  LEU L2 CD2 1 
ATOM 4594 N N   . ALA B 2 34  ? 99.084  88.227  -66.402 1.00 30.48  ? 34  ALA L2 N   1 
ATOM 4595 C CA  . ALA B 2 34  ? 99.394  89.404  -65.614 1.00 28.57  ? 34  ALA L2 CA  1 
ATOM 4596 C C   . ALA B 2 34  ? 100.633 90.079  -66.173 1.00 26.97  ? 34  ALA L2 C   1 
ATOM 4597 O O   . ALA B 2 34  ? 101.527 89.420  -66.704 1.00 24.47  ? 34  ALA L2 O   1 
ATOM 4598 C CB  . ALA B 2 34  ? 99.626  89.058  -64.148 1.00 28.56  ? 34  ALA L2 CB  1 
ATOM 4599 N N   . TRP B 2 35  ? 100.686 91.401  -66.034 1.00 25.64  ? 35  TRP L2 N   1 
ATOM 4600 C CA  . TRP B 2 35  ? 101.806 92.206  -66.498 1.00 24.82  ? 35  TRP L2 CA  1 
ATOM 4601 C C   . TRP B 2 35  ? 102.467 92.907  -65.325 1.00 24.88  ? 35  TRP L2 C   1 
ATOM 4602 O O   . TRP B 2 35  ? 101.799 93.576  -64.535 1.00 25.28  ? 35  TRP L2 O   1 
ATOM 4603 C CB  . TRP B 2 35  ? 101.352 93.244  -67.512 1.00 25.05  ? 35  TRP L2 CB  1 
ATOM 4604 C CG  . TRP B 2 35  ? 101.023 92.665  -68.819 1.00 27.39  ? 35  TRP L2 CG  1 
ATOM 4605 C CD1 . TRP B 2 35  ? 99.785  92.434  -69.324 1.00 25.83  ? 35  TRP L2 CD1 1 
ATOM 4606 C CD2 . TRP B 2 35  ? 101.947 92.225  -69.803 1.00 27.33  ? 35  TRP L2 CD2 1 
ATOM 4607 N NE1 . TRP B 2 35  ? 99.880  91.876  -70.570 1.00 27.40  ? 35  TRP L2 NE1 1 
ATOM 4608 C CE2 . TRP B 2 35  ? 101.203 91.740  -70.886 1.00 29.03  ? 35  TRP L2 CE2 1 
ATOM 4609 C CE3 . TRP B 2 35  ? 103.337 92.199  -69.877 1.00 29.37  ? 35  TRP L2 CE3 1 
ATOM 4610 C CZ2 . TRP B 2 35  ? 101.804 91.235  -72.023 1.00 29.65  ? 35  TRP L2 CZ2 1 
ATOM 4611 C CZ3 . TRP B 2 35  ? 103.923 91.698  -71.001 1.00 30.43  ? 35  TRP L2 CZ3 1 
ATOM 4612 C CH2 . TRP B 2 35  ? 103.164 91.230  -72.061 1.00 29.62  ? 35  TRP L2 CH2 1 
ATOM 4613 N N   . TYR B 2 36  ? 103.781 92.772  -65.229 1.00 24.23  ? 36  TYR L2 N   1 
ATOM 4614 C CA  . TYR B 2 36  ? 104.544 93.295  -64.110 1.00 23.43  ? 36  TYR L2 CA  1 
ATOM 4615 C C   . TYR B 2 36  ? 105.590 94.284  -64.592 1.00 23.15  ? 36  TYR L2 C   1 
ATOM 4616 O O   . TYR B 2 36  ? 106.223 94.070  -65.627 1.00 21.49  ? 36  TYR L2 O   1 
ATOM 4617 C CB  . TYR B 2 36  ? 105.225 92.174  -63.355 1.00 23.65  ? 36  TYR L2 CB  1 
ATOM 4618 C CG  . TYR B 2 36  ? 104.268 91.348  -62.558 1.00 26.65  ? 36  TYR L2 CG  1 
ATOM 4619 C CD1 . TYR B 2 36  ? 103.818 90.129  -63.029 1.00 28.91  ? 36  TYR L2 CD1 1 
ATOM 4620 C CD2 . TYR B 2 36  ? 103.799 91.797  -61.338 1.00 25.72  ? 36  TYR L2 CD2 1 
ATOM 4621 C CE1 . TYR B 2 36  ? 102.936 89.385  -62.303 1.00 30.77  ? 36  TYR L2 CE1 1 
ATOM 4622 C CE2 . TYR B 2 36  ? 102.921 91.059  -60.609 1.00 29.31  ? 36  TYR L2 CE2 1 
ATOM 4623 C CZ  . TYR B 2 36  ? 102.492 89.860  -61.096 1.00 30.68  ? 36  TYR L2 CZ  1 
ATOM 4624 O OH  . TYR B 2 36  ? 101.616 89.116  -60.366 1.00 29.62  ? 36  TYR L2 OH  1 
ATOM 4625 N N   . GLN B 2 37  ? 105.775 95.353  -63.828 1.00 23.45  ? 37  GLN L2 N   1 
ATOM 4626 C CA  . GLN B 2 37  ? 106.796 96.360  -64.088 1.00 24.05  ? 37  GLN L2 CA  1 
ATOM 4627 C C   . GLN B 2 37  ? 107.802 96.330  -62.955 1.00 23.87  ? 37  GLN L2 C   1 
ATOM 4628 O O   . GLN B 2 37  ? 107.438 96.562  -61.799 1.00 23.50  ? 37  GLN L2 O   1 
ATOM 4629 C CB  . GLN B 2 37  ? 106.185 97.752  -64.197 1.00 24.58  ? 37  GLN L2 CB  1 
ATOM 4630 C CG  . GLN B 2 37  ? 107.183 98.847  -64.480 1.00 26.16  ? 37  GLN L2 CG  1 
ATOM 4631 C CD  . GLN B 2 37  ? 106.538 100.209 -64.489 1.00 27.66  ? 37  GLN L2 CD  1 
ATOM 4632 O OE1 . GLN B 2 37  ? 106.014 100.665 -63.476 1.00 26.93  ? 37  GLN L2 OE1 1 
ATOM 4633 N NE2 . GLN B 2 37  ? 106.544 100.856 -65.642 1.00 26.86  ? 37  GLN L2 NE2 1 
ATOM 4634 N N   . GLN B 2 38  ? 109.057 96.057  -63.275 1.00 22.76  ? 38  GLN L2 N   1 
ATOM 4635 C CA  . GLN B 2 38  ? 110.108 95.999  -62.268 1.00 23.43  ? 38  GLN L2 CA  1 
ATOM 4636 C C   . GLN B 2 38  ? 111.236 96.940  -62.655 1.00 24.74  ? 38  GLN L2 C   1 
ATOM 4637 O O   . GLN B 2 38  ? 111.997 96.652  -63.583 1.00 22.90  ? 38  GLN L2 O   1 
ATOM 4638 C CB  . GLN B 2 38  ? 110.635 94.579  -62.105 1.00 22.35  ? 38  GLN L2 CB  1 
ATOM 4639 C CG  . GLN B 2 38  ? 111.670 94.464  -61.014 1.00 21.93  ? 38  GLN L2 CG  1 
ATOM 4640 C CD  . GLN B 2 38  ? 112.410 93.156  -61.055 1.00 23.72  ? 38  GLN L2 CD  1 
ATOM 4641 O OE1 . GLN B 2 38  ? 112.248 92.369  -61.978 1.00 23.13  ? 38  GLN L2 OE1 1 
ATOM 4642 N NE2 . GLN B 2 38  ? 113.227 92.910  -60.044 1.00 19.68  ? 38  GLN L2 NE2 1 
ATOM 4643 N N   . ILE B 2 39  ? 111.333 98.069  -61.957 1.00 27.70  ? 39  ILE L2 N   1 
ATOM 4644 C CA  . ILE B 2 39  ? 112.604 98.794  -61.995 1.00 30.37  ? 39  ILE L2 CA  1 
ATOM 4645 C C   . ILE B 2 39  ? 113.646 97.947  -61.283 1.00 30.44  ? 39  ILE L2 C   1 
ATOM 4646 O O   . ILE B 2 39  ? 113.316 97.292  -60.273 1.00 27.64  ? 39  ILE L2 O   1 
ATOM 4647 C CB  . ILE B 2 39  ? 112.469 100.180 -61.346 1.00 32.05  ? 39  ILE L2 CB  1 
ATOM 4648 C CG1 . ILE B 2 39  ? 111.605 100.110 -60.089 1.00 34.90  ? 39  ILE L2 CG1 1 
ATOM 4649 C CG2 . ILE B 2 39  ? 111.884 101.167 -62.331 1.00 32.92  ? 39  ILE L2 CG2 1 
ATOM 4650 C CD1 . ILE B 2 39  ? 111.546 101.404 -59.318 1.00 38.85  ? 39  ILE L2 CD1 1 
ATOM 4651 N N   . PRO B 2 40  ? 114.885 97.876  -61.765 1.00 32.57  ? 40  PRO L2 N   1 
ATOM 4652 C CA  . PRO B 2 40  ? 115.819 96.863  -61.253 1.00 33.17  ? 40  PRO L2 CA  1 
ATOM 4653 C C   . PRO B 2 40  ? 116.294 97.191  -59.845 1.00 34.12  ? 40  PRO L2 C   1 
ATOM 4654 O O   . PRO B 2 40  ? 116.449 98.357  -59.479 1.00 33.39  ? 40  PRO L2 O   1 
ATOM 4655 C CB  . PRO B 2 40  ? 116.971 96.897  -62.264 1.00 34.19  ? 40  PRO L2 CB  1 
ATOM 4656 C CG  . PRO B 2 40  ? 116.392 97.561  -63.482 1.00 34.25  ? 40  PRO L2 CG  1 
ATOM 4657 C CD  . PRO B 2 40  ? 115.428 98.564  -62.944 1.00 33.34  ? 40  PRO L2 CD  1 
ATOM 4658 N N   . GLY B 2 41  ? 116.504 96.140  -59.053 1.00 35.04  ? 41  GLY L2 N   1 
ATOM 4659 C CA  . GLY B 2 41  ? 116.785 96.298  -57.641 1.00 36.43  ? 41  GLY L2 CA  1 
ATOM 4660 C C   . GLY B 2 41  ? 115.556 96.470  -56.780 1.00 35.70  ? 41  GLY L2 C   1 
ATOM 4661 O O   . GLY B 2 41  ? 115.682 96.637  -55.566 1.00 36.81  ? 41  GLY L2 O   1 
ATOM 4662 N N   . GLN B 2 42  ? 114.367 96.429  -57.375 1.00 34.32  ? 42  GLN L2 N   1 
ATOM 4663 C CA  . GLN B 2 42  ? 113.114 96.648  -56.668 1.00 33.21  ? 42  GLN L2 CA  1 
ATOM 4664 C C   . GLN B 2 42  ? 112.186 95.466  -56.911 1.00 31.24  ? 42  GLN L2 C   1 
ATOM 4665 O O   . GLN B 2 42  ? 112.446 94.603  -57.752 1.00 27.44  ? 42  GLN L2 O   1 
ATOM 4666 C CB  . GLN B 2 42  ? 112.448 97.953  -57.115 1.00 35.32  ? 42  GLN L2 CB  1 
ATOM 4667 C CG  . GLN B 2 42  ? 113.286 99.186  -56.880 1.00 39.57  ? 42  GLN L2 CG  1 
ATOM 4668 C CD  . GLN B 2 42  ? 113.495 99.469  -55.411 1.00 41.79  ? 42  GLN L2 CD  1 
ATOM 4669 O OE1 . GLN B 2 42  ? 114.626 99.621  -54.949 1.00 43.78  ? 42  GLN L2 OE1 1 
ATOM 4670 N NE2 . GLN B 2 42  ? 112.403 99.541  -54.664 1.00 43.73  ? 42  GLN L2 NE2 1 
ATOM 4671 N N   . SER B 2 43  ? 111.094 95.438  -56.167 1.00 29.47  ? 43  SER L2 N   1 
ATOM 4672 C CA  . SER B 2 43  ? 110.078 94.416  -56.343 1.00 29.58  ? 43  SER L2 CA  1 
ATOM 4673 C C   . SER B 2 43  ? 109.227 94.744  -57.563 1.00 27.80  ? 43  SER L2 C   1 
ATOM 4674 O O   . SER B 2 43  ? 109.021 95.921  -57.866 1.00 26.18  ? 43  SER L2 O   1 
ATOM 4675 C CB  . SER B 2 43  ? 109.194 94.334  -55.113 1.00 31.15  ? 43  SER L2 CB  1 
ATOM 4676 O OG  . SER B 2 43  ? 109.973 94.124  -53.954 1.00 33.84  ? 43  SER L2 OG  1 
ATOM 4677 N N   . PRO B 2 44  ? 108.748 93.738  -58.292 1.00 27.03  ? 44  PRO L2 N   1 
ATOM 4678 C CA  . PRO B 2 44  ? 107.864 94.016  -59.427 1.00 27.55  ? 44  PRO L2 CA  1 
ATOM 4679 C C   . PRO B 2 44  ? 106.534 94.575  -58.958 1.00 27.77  ? 44  PRO L2 C   1 
ATOM 4680 O O   . PRO B 2 44  ? 106.128 94.385  -57.813 1.00 27.82  ? 44  PRO L2 O   1 
ATOM 4681 C CB  . PRO B 2 44  ? 107.696 92.651  -60.095 1.00 27.15  ? 44  PRO L2 CB  1 
ATOM 4682 C CG  . PRO B 2 44  ? 108.868 91.870  -59.650 1.00 26.77  ? 44  PRO L2 CG  1 
ATOM 4683 C CD  . PRO B 2 44  ? 109.200 92.339  -58.282 1.00 28.08  ? 44  PRO L2 CD  1 
ATOM 4684 N N   . LYS B 2 45  ? 105.879 95.302  -59.844 1.00 28.33  ? 45  LYS L2 N   1 
ATOM 4685 C CA  . LYS B 2 45  ? 104.613 95.939  -59.537 1.00 28.88  ? 45  LYS L2 CA  1 
ATOM 4686 C C   . LYS B 2 45  ? 103.543 95.423  -60.484 1.00 27.59  ? 45  LYS L2 C   1 
ATOM 4687 O O   . LYS B 2 45  ? 103.738 95.400  -61.700 1.00 25.84  ? 45  LYS L2 O   1 
ATOM 4688 C CB  . LYS B 2 45  ? 104.739 97.454  -59.654 1.00 32.41  ? 45  LYS L2 CB  1 
ATOM 4689 C CG  . LYS B 2 45  ? 103.501 98.220  -59.255 1.00 39.03  ? 45  LYS L2 CG  1 
ATOM 4690 C CD  . LYS B 2 45  ? 103.430 99.574  -59.941 1.00 43.29  ? 45  LYS L2 CD  1 
ATOM 4691 C CE  . LYS B 2 45  ? 104.750 100.327 -59.863 1.00 46.03  ? 45  LYS L2 CE  1 
ATOM 4692 N NZ  . LYS B 2 45  ? 105.147 100.604 -58.456 1.00 47.33  ? 45  LYS L2 NZ  1 
ATOM 4693 N N   . LEU B 2 46  ? 102.412 95.011  -59.927 1.00 24.85  ? 46  LEU L2 N   1 
ATOM 4694 C CA  . LEU B 2 46  ? 101.340 94.448  -60.734 1.00 25.39  ? 46  LEU L2 CA  1 
ATOM 4695 C C   . LEU B 2 46  ? 100.596 95.566  -61.445 1.00 27.06  ? 46  LEU L2 C   1 
ATOM 4696 O O   . LEU B 2 46  ? 100.007 96.435  -60.796 1.00 27.59  ? 46  LEU L2 O   1 
ATOM 4697 C CB  . LEU B 2 46  ? 100.386 93.637  -59.863 1.00 24.74  ? 46  LEU L2 CB  1 
ATOM 4698 C CG  . LEU B 2 46  ? 99.089  93.185  -60.527 1.00 23.63  ? 46  LEU L2 CG  1 
ATOM 4699 C CD1 . LEU B 2 46  ? 99.361  92.089  -61.516 1.00 23.29  ? 46  LEU L2 CD1 1 
ATOM 4700 C CD2 . LEU B 2 46  ? 98.099  92.741  -59.487 1.00 26.37  ? 46  LEU L2 CD2 1 
ATOM 4701 N N   . LEU B 2 47  ? 100.629 95.555  -62.775 1.00 28.22  ? 47  LEU L2 N   1 
ATOM 4702 C CA  . LEU B 2 47  ? 99.905  96.541  -63.566 1.00 28.98  ? 47  LEU L2 CA  1 
ATOM 4703 C C   . LEU B 2 47  ? 98.578  95.999  -64.079 1.00 30.17  ? 47  LEU L2 C   1 
ATOM 4704 O O   . LEU B 2 47  ? 97.522  96.576  -63.820 1.00 29.57  ? 47  LEU L2 O   1 
ATOM 4705 C CB  . LEU B 2 47  ? 100.761 97.006  -64.748 1.00 28.29  ? 47  LEU L2 CB  1 
ATOM 4706 C CG  . LEU B 2 47  ? 102.216 97.384  -64.516 1.00 28.05  ? 47  LEU L2 CG  1 
ATOM 4707 C CD1 . LEU B 2 47  ? 102.936 97.257  -65.822 1.00 30.62  ? 47  LEU L2 CD1 1 
ATOM 4708 C CD2 . LEU B 2 47  ? 102.310 98.789  -63.994 1.00 28.02  ? 47  LEU L2 CD2 1 
ATOM 4709 N N   . ILE B 2 48  ? 98.620  94.898  -64.819 1.00 30.94  ? 48  ILE L2 N   1 
ATOM 4710 C CA  . ILE B 2 48  ? 97.458  94.340  -65.498 1.00 31.15  ? 48  ILE L2 CA  1 
ATOM 4711 C C   . ILE B 2 48  ? 97.210  92.952  -64.931 1.00 32.10  ? 48  ILE L2 C   1 
ATOM 4712 O O   . ILE B 2 48  ? 98.163  92.218  -64.666 1.00 32.35  ? 48  ILE L2 O   1 
ATOM 4713 C CB  . ILE B 2 48  ? 97.679  94.288  -67.020 1.00 30.22  ? 48  ILE L2 CB  1 
ATOM 4714 C CG1 . ILE B 2 48  ? 98.018  95.677  -67.553 1.00 26.97  ? 48  ILE L2 CG1 1 
ATOM 4715 C CG2 . ILE B 2 48  ? 96.469  93.756  -67.738 1.00 30.42  ? 48  ILE L2 CG2 1 
ATOM 4716 C CD1 . ILE B 2 48  ? 96.908  96.678  -67.395 1.00 27.90  ? 48  ILE L2 CD1 1 
ATOM 4717 N N   . TYR B 2 49  ? 95.947  92.615  -64.692 1.00 33.39  ? 49  TYR L2 N   1 
ATOM 4718 C CA  . TYR B 2 49  ? 95.555  91.251  -64.382 1.00 35.79  ? 49  TYR L2 CA  1 
ATOM 4719 C C   . TYR B 2 49  ? 94.432  90.833  -65.311 1.00 35.92  ? 49  TYR L2 C   1 
ATOM 4720 O O   . TYR B 2 49  ? 93.642  91.664  -65.763 1.00 36.09  ? 49  TYR L2 O   1 
ATOM 4721 C CB  . TYR B 2 49  ? 95.123  91.082  -62.920 1.00 35.92  ? 49  TYR L2 CB  1 
ATOM 4722 C CG  . TYR B 2 49  ? 94.046  92.024  -62.443 1.00 39.91  ? 49  TYR L2 CG  1 
ATOM 4723 C CD1 . TYR B 2 49  ? 94.366  93.266  -61.929 1.00 40.59  ? 49  TYR L2 CD1 1 
ATOM 4724 C CD2 . TYR B 2 49  ? 92.715  91.653  -62.468 1.00 40.08  ? 49  TYR L2 CD2 1 
ATOM 4725 C CE1 . TYR B 2 49  ? 93.394  94.116  -61.488 1.00 40.71  ? 49  TYR L2 CE1 1 
ATOM 4726 C CE2 . TYR B 2 49  ? 91.734  92.498  -62.024 1.00 40.68  ? 49  TYR L2 CE2 1 
ATOM 4727 C CZ  . TYR B 2 49  ? 92.080  93.727  -61.535 1.00 40.56  ? 49  TYR L2 CZ  1 
ATOM 4728 O OH  . TYR B 2 49  ? 91.106  94.584  -61.087 1.00 40.57  ? 49  TYR L2 OH  1 
ATOM 4729 N N   . SER B 2 50  ? 94.412  89.533  -65.614 1.00 36.39  ? 50  SER L2 N   1 
ATOM 4730 C CA  . SER B 2 50  ? 93.472  88.898  -66.547 1.00 37.24  ? 50  SER L2 CA  1 
ATOM 4731 C C   . SER B 2 50  ? 93.556  89.511  -67.941 1.00 38.15  ? 50  SER L2 C   1 
ATOM 4732 O O   . SER B 2 50  ? 92.553  89.629  -68.646 1.00 36.78  ? 50  SER L2 O   1 
ATOM 4733 C CB  . SER B 2 50  ? 92.037  88.938  -66.020 1.00 37.48  ? 50  SER L2 CB  1 
ATOM 4734 O OG  . SER B 2 50  ? 91.937  88.310  -64.760 1.00 39.94  ? 50  SER L2 OG  1 
ATOM 4735 N N   . ALA B 2 51  ? 94.755  89.984  -68.298 1.00 37.95  ? 51  ALA L2 N   1 
ATOM 4736 C CA  . ALA B 2 51  ? 95.177  90.450  -69.620 1.00 38.76  ? 51  ALA L2 CA  1 
ATOM 4737 C C   . ALA B 2 51  ? 94.473  91.706  -70.114 1.00 39.14  ? 51  ALA L2 C   1 
ATOM 4738 O O   . ALA B 2 51  ? 94.822  92.223  -71.176 1.00 39.06  ? 51  ALA L2 O   1 
ATOM 4739 C CB  . ALA B 2 51  ? 95.015  89.350  -70.667 1.00 39.66  ? 51  ALA L2 CB  1 
ATOM 4740 N N   . SER B 2 52  ? 93.495  92.206  -69.387 1.00 40.05  ? 52  SER L2 N   1 
ATOM 4741 C CA  . SER B 2 52  ? 92.814  93.427  -69.788 1.00 41.16  ? 52  SER L2 CA  1 
ATOM 4742 C C   . SER B 2 52  ? 92.589  94.413  -68.657 1.00 41.31  ? 52  SER L2 C   1 
ATOM 4743 O O   . SER B 2 52  ? 92.524  95.615  -68.923 1.00 42.00  ? 52  SER L2 O   1 
ATOM 4744 C CB  . SER B 2 52  ? 91.462  93.088  -70.423 1.00 42.65  ? 52  SER L2 CB  1 
ATOM 4745 O OG  . SER B 2 52  ? 90.965  94.176  -71.177 1.00 43.56  ? 52  SER L2 OG  1 
ATOM 4746 N N   . ASN B 2 53  ? 92.478  93.964  -67.413 1.00 41.56  ? 53  ASN L2 N   1 
ATOM 4747 C CA  . ASN B 2 53  ? 92.029  94.832  -66.341 1.00 42.24  ? 53  ASN L2 CA  1 
ATOM 4748 C C   . ASN B 2 53  ? 93.208  95.531  -65.696 1.00 42.88  ? 53  ASN L2 C   1 
ATOM 4749 O O   . ASN B 2 53  ? 94.234  94.917  -65.413 1.00 43.35  ? 53  ASN L2 O   1 
ATOM 4750 C CB  . ASN B 2 53  ? 91.260  94.034  -65.295 1.00 42.39  ? 53  ASN L2 CB  1 
ATOM 4751 C CG  . ASN B 2 53  ? 90.143  93.225  -65.901 1.00 42.31  ? 53  ASN L2 CG  1 
ATOM 4752 O OD1 . ASN B 2 53  ? 89.056  93.736  -66.145 1.00 41.10  ? 53  ASN L2 OD1 1 
ATOM 4753 N ND2 . ASN B 2 53  ? 90.407  91.955  -66.158 1.00 42.03  ? 53  ASN L2 ND2 1 
ATOM 4754 N N   . ARG B 2 54  ? 93.054  96.824  -65.472 1.00 43.75  ? 54  ARG L2 N   1 
ATOM 4755 C CA  . ARG B 2 54  ? 94.082  97.621  -64.836 1.00 46.38  ? 54  ARG L2 CA  1 
ATOM 4756 C C   . ARG B 2 54  ? 93.973  97.499  -63.325 1.00 46.90  ? 54  ARG L2 C   1 
ATOM 4757 O O   . ARG B 2 54  ? 92.876  97.499  -62.764 1.00 48.14  ? 54  ARG L2 O   1 
ATOM 4758 C CB  . ARG B 2 54  ? 93.927  99.079  -65.253 1.00 46.48  ? 54  ARG L2 CB  1 
ATOM 4759 C CG  . ARG B 2 54  ? 95.153  99.933  -65.097 1.00 47.18  ? 54  ARG L2 CG  1 
ATOM 4760 C CD  . ARG B 2 54  ? 94.898  101.320 -65.652 1.00 48.26  ? 54  ARG L2 CD  1 
ATOM 4761 N NE  . ARG B 2 54  ? 94.487  101.270 -67.050 1.00 48.87  ? 54  ARG L2 NE  1 
ATOM 4762 C CZ  . ARG B 2 54  ? 93.351  101.774 -67.513 1.00 49.29  ? 54  ARG L2 CZ  1 
ATOM 4763 N NH1 . ARG B 2 54  ? 92.510  102.374 -66.690 1.00 49.74  ? 54  ARG L2 NH1 1 
ATOM 4764 N NH2 . ARG B 2 54  ? 93.059  101.681 -68.801 1.00 49.44  ? 54  ARG L2 NH2 1 
ATOM 4765 N N   . TYR B 2 55  ? 95.117  97.397  -62.667 1.00 47.27  ? 55  TYR L2 N   1 
ATOM 4766 C CA  . TYR B 2 55  ? 95.142  97.396  -61.214 1.00 47.42  ? 55  TYR L2 CA  1 
ATOM 4767 C C   . TYR B 2 55  ? 94.793  98.786  -60.691 1.00 47.20  ? 55  TYR L2 C   1 
ATOM 4768 O O   . TYR B 2 55  ? 94.973  99.793  -61.377 1.00 46.33  ? 55  TYR L2 O   1 
ATOM 4769 C CB  . TYR B 2 55  ? 96.511  96.951  -60.704 1.00 48.34  ? 55  TYR L2 CB  1 
ATOM 4770 C CG  . TYR B 2 55  ? 96.542  96.638  -59.234 1.00 50.30  ? 55  TYR L2 CG  1 
ATOM 4771 C CD1 . TYR B 2 55  ? 95.504  95.949  -58.635 1.00 50.53  ? 55  TYR L2 CD1 1 
ATOM 4772 C CD2 . TYR B 2 55  ? 97.606  97.037  -58.445 1.00 51.44  ? 55  TYR L2 CD2 1 
ATOM 4773 C CE1 . TYR B 2 55  ? 95.520  95.671  -57.290 1.00 50.84  ? 55  TYR L2 CE1 1 
ATOM 4774 C CE2 . TYR B 2 55  ? 97.634  96.757  -57.100 1.00 51.54  ? 55  TYR L2 CE2 1 
ATOM 4775 C CZ  . TYR B 2 55  ? 96.588  96.074  -56.529 1.00 51.86  ? 55  TYR L2 CZ  1 
ATOM 4776 O OH  . TYR B 2 55  ? 96.602  95.789  -55.187 1.00 53.99  ? 55  TYR L2 OH  1 
ATOM 4777 N N   . THR B 2 56  ? 94.265  98.823  -59.471 1.00 47.31  ? 56  THR L2 N   1 
ATOM 4778 C CA  . THR B 2 56  ? 93.807  100.067 -58.865 1.00 47.97  ? 56  THR L2 CA  1 
ATOM 4779 C C   . THR B 2 56  ? 94.985  100.975 -58.551 1.00 47.44  ? 56  THR L2 C   1 
ATOM 4780 O O   . THR B 2 56  ? 95.901  100.590 -57.816 1.00 48.24  ? 56  THR L2 O   1 
ATOM 4781 C CB  . THR B 2 56  ? 93.042  99.773  -57.583 1.00 49.07  ? 56  THR L2 CB  1 
ATOM 4782 O OG1 . THR B 2 56  ? 93.945  99.216  -56.624 1.00 51.32  ? 56  THR L2 OG1 1 
ATOM 4783 C CG2 . THR B 2 56  ? 91.932  98.775  -57.844 1.00 50.41  ? 56  THR L2 CG2 1 
ATOM 4784 N N   . GLY B 2 57  ? 94.952  102.191 -59.093 1.00 46.62  ? 57  GLY L2 N   1 
ATOM 4785 C CA  . GLY B 2 57  ? 96.036  103.130 -58.929 1.00 44.28  ? 57  GLY L2 CA  1 
ATOM 4786 C C   . GLY B 2 57  ? 97.074  103.114 -60.029 1.00 43.66  ? 57  GLY L2 C   1 
ATOM 4787 O O   . GLY B 2 57  ? 97.952  103.983 -60.039 1.00 43.95  ? 57  GLY L2 O   1 
ATOM 4788 N N   . VAL B 2 58  ? 97.018  102.153 -60.939 1.00 41.89  ? 58  VAL L2 N   1 
ATOM 4789 C CA  . VAL B 2 58  ? 97.908  102.172 -62.103 1.00 41.38  ? 58  VAL L2 CA  1 
ATOM 4790 C C   . VAL B 2 58  ? 97.414  103.238 -63.077 1.00 40.76  ? 58  VAL L2 C   1 
ATOM 4791 O O   . VAL B 2 58  ? 96.203  103.305 -63.348 1.00 40.18  ? 58  VAL L2 O   1 
ATOM 4792 C CB  . VAL B 2 58  ? 97.952  100.788 -62.754 1.00 40.90  ? 58  VAL L2 CB  1 
ATOM 4793 C CG1 . VAL B 2 58  ? 98.640  100.821 -64.104 1.00 41.37  ? 58  VAL L2 CG1 1 
ATOM 4794 C CG2 . VAL B 2 58  ? 98.669  99.823  -61.839 1.00 40.05  ? 58  VAL L2 CG2 1 
ATOM 4795 N N   . PRO B 2 59  ? 98.284  104.115 -63.578 1.00 40.57  ? 59  PRO L2 N   1 
ATOM 4796 C CA  . PRO B 2 59  ? 97.827  105.180 -64.478 1.00 40.40  ? 59  PRO L2 CA  1 
ATOM 4797 C C   . PRO B 2 59  ? 97.399  104.642 -65.835 1.00 40.10  ? 59  PRO L2 C   1 
ATOM 4798 O O   . PRO B 2 59  ? 97.816  103.572 -66.281 1.00 38.65  ? 59  PRO L2 O   1 
ATOM 4799 C CB  . PRO B 2 59  ? 99.051  106.090 -64.602 1.00 40.93  ? 59  PRO L2 CB  1 
ATOM 4800 C CG  . PRO B 2 59  ? 100.195 105.231 -64.248 1.00 42.14  ? 59  PRO L2 CG  1 
ATOM 4801 C CD  . PRO B 2 59  ? 99.709  104.251 -63.244 1.00 41.54  ? 59  PRO L2 CD  1 
ATOM 4802 N N   . ASP B 2 60  ? 96.560  105.430 -66.501 1.00 40.77  ? 60  ASP L2 N   1 
ATOM 4803 C CA  . ASP B 2 60  ? 95.766  104.955 -67.625 1.00 42.42  ? 60  ASP L2 CA  1 
ATOM 4804 C C   . ASP B 2 60  ? 96.517  104.913 -68.944 1.00 42.21  ? 60  ASP L2 C   1 
ATOM 4805 O O   . ASP B 2 60  ? 95.909  104.587 -69.965 1.00 41.06  ? 60  ASP L2 O   1 
ATOM 4806 C CB  . ASP B 2 60  ? 94.525  105.828 -67.775 1.00 43.85  ? 60  ASP L2 CB  1 
ATOM 4807 C CG  . ASP B 2 60  ? 93.752  105.941 -66.488 1.00 44.64  ? 60  ASP L2 CG  1 
ATOM 4808 O OD1 . ASP B 2 60  ? 92.614  105.431 -66.427 1.00 43.23  ? 60  ASP L2 OD1 1 
ATOM 4809 O OD2 . ASP B 2 60  ? 94.290  106.528 -65.528 1.00 46.85  ? 60  ASP L2 OD2 1 
ATOM 4810 N N   . ARG B 2 61  ? 97.808  105.229 -68.961 1.00 42.22  ? 61  ARG L2 N   1 
ATOM 4811 C CA  . ARG B 2 61  ? 98.555  105.091 -70.199 1.00 41.09  ? 61  ARG L2 CA  1 
ATOM 4812 C C   . ARG B 2 61  ? 98.900  103.645 -70.511 1.00 40.32  ? 61  ARG L2 C   1 
ATOM 4813 O O   . ARG B 2 61  ? 99.110  103.318 -71.682 1.00 40.64  ? 61  ARG L2 O   1 
ATOM 4814 C CB  . ARG B 2 61  ? 99.821  105.938 -70.140 1.00 42.85  ? 61  ARG L2 CB  1 
ATOM 4815 C CG  . ARG B 2 61  ? 100.699 105.646 -68.952 1.00 44.36  ? 61  ARG L2 CG  1 
ATOM 4816 C CD  . ARG B 2 61  ? 101.812 106.655 -68.835 1.00 46.04  ? 61  ARG L2 CD  1 
ATOM 4817 N NE  . ARG B 2 61  ? 102.797 106.231 -67.851 1.00 47.45  ? 61  ARG L2 NE  1 
ATOM 4818 C CZ  . ARG B 2 61  ? 102.799 106.615 -66.582 1.00 49.23  ? 61  ARG L2 CZ  1 
ATOM 4819 N NH1 . ARG B 2 61  ? 103.739 106.174 -65.759 1.00 49.91  ? 61  ARG L2 NH1 1 
ATOM 4820 N NH2 . ARG B 2 61  ? 101.873 107.448 -66.141 1.00 51.07  ? 61  ARG L2 NH2 1 
ATOM 4821 N N   . PHE B 2 62  ? 98.945  102.773 -69.505 1.00 38.44  ? 62  PHE L2 N   1 
ATOM 4822 C CA  . PHE B 2 62  ? 99.136  101.343 -69.707 1.00 37.33  ? 62  PHE L2 CA  1 
ATOM 4823 C C   . PHE B 2 62  ? 97.804  100.707 -70.073 1.00 37.26  ? 62  PHE L2 C   1 
ATOM 4824 O O   . PHE B 2 62  ? 96.860  100.738 -69.279 1.00 36.63  ? 62  PHE L2 O   1 
ATOM 4825 C CB  . PHE B 2 62  ? 99.674  100.652 -68.457 1.00 38.07  ? 62  PHE L2 CB  1 
ATOM 4826 C CG  . PHE B 2 62  ? 100.889 101.285 -67.861 1.00 37.88  ? 62  PHE L2 CG  1 
ATOM 4827 C CD1 . PHE B 2 62  ? 102.149 100.882 -68.245 1.00 38.53  ? 62  PHE L2 CD1 1 
ATOM 4828 C CD2 . PHE B 2 62  ? 100.771 102.236 -66.867 1.00 38.14  ? 62  PHE L2 CD2 1 
ATOM 4829 C CE1 . PHE B 2 62  ? 103.268 101.435 -67.674 1.00 38.84  ? 62  PHE L2 CE1 1 
ATOM 4830 C CE2 . PHE B 2 62  ? 101.887 102.793 -66.297 1.00 39.07  ? 62  PHE L2 CE2 1 
ATOM 4831 C CZ  . PHE B 2 62  ? 103.135 102.389 -66.700 1.00 38.07  ? 62  PHE L2 CZ  1 
ATOM 4832 N N   . THR B 2 63  ? 97.731  100.133 -71.268 1.00 36.62  ? 63  THR L2 N   1 
ATOM 4833 C CA  . THR B 2 63  ? 96.613  99.290  -71.653 1.00 37.18  ? 63  THR L2 CA  1 
ATOM 4834 C C   . THR B 2 63  ? 97.170  97.956  -72.110 1.00 37.49  ? 63  THR L2 C   1 
ATOM 4835 O O   . THR B 2 63  ? 98.318  97.868  -72.547 1.00 37.42  ? 63  THR L2 O   1 
ATOM 4836 C CB  . THR B 2 63  ? 95.761  99.907  -72.770 1.00 36.96  ? 63  THR L2 CB  1 
ATOM 4837 O OG1 . THR B 2 63  ? 96.565  100.096 -73.940 1.00 37.57  ? 63  THR L2 OG1 1 
ATOM 4838 C CG2 . THR B 2 63  ? 95.179  101.245 -72.337 1.00 37.60  ? 63  THR L2 CG2 1 
ATOM 4839 N N   . ALA B 2 64  ? 96.354  96.914  -72.000 1.00 35.81  ? 64  ALA L2 N   1 
ATOM 4840 C CA  . ALA B 2 64  ? 96.781  95.587  -72.409 1.00 36.06  ? 64  ALA L2 CA  1 
ATOM 4841 C C   . ALA B 2 64  ? 95.619  94.867  -73.066 1.00 37.07  ? 64  ALA L2 C   1 
ATOM 4842 O O   . ALA B 2 64  ? 94.454  95.214  -72.857 1.00 36.66  ? 64  ALA L2 O   1 
ATOM 4843 C CB  . ALA B 2 64  ? 97.306  94.768  -71.231 1.00 37.83  ? 64  ALA L2 CB  1 
ATOM 4844 N N   . SER B 2 65  ? 95.950  93.857  -73.859 1.00 38.02  ? 65  SER L2 N   1 
ATOM 4845 C CA  . SER B 2 65  ? 94.955  93.134  -74.628 1.00 39.67  ? 65  SER L2 CA  1 
ATOM 4846 C C   . SER B 2 65  ? 95.418  91.700  -74.812 1.00 39.39  ? 65  SER L2 C   1 
ATOM 4847 O O   . SER B 2 65  ? 96.423  91.269  -74.247 1.00 40.05  ? 65  SER L2 O   1 
ATOM 4848 C CB  . SER B 2 65  ? 94.713  93.802  -75.981 1.00 40.16  ? 65  SER L2 CB  1 
ATOM 4849 O OG  . SER B 2 65  ? 93.847  93.025  -76.784 1.00 43.04  ? 65  SER L2 OG  1 
ATOM 4850 N N   . GLY B 2 66  ? 94.659  90.959  -75.607 1.00 39.48  ? 66  GLY L2 N   1 
ATOM 4851 C CA  . GLY B 2 66  ? 95.048  89.613  -75.965 1.00 39.78  ? 66  GLY L2 CA  1 
ATOM 4852 C C   . GLY B 2 66  ? 94.182  88.546  -75.342 1.00 40.59  ? 66  GLY L2 C   1 
ATOM 4853 O O   . GLY B 2 66  ? 93.713  88.698  -74.213 1.00 41.41  ? 66  GLY L2 O   1 
ATOM 4854 N N   . SER B 2 67  ? 93.978  87.454  -76.071 1.00 41.51  ? 67  SER L2 N   1 
ATOM 4855 C CA  . SER B 2 67  ? 93.231  86.311  -75.572 1.00 42.62  ? 67  SER L2 CA  1 
ATOM 4856 C C   . SER B 2 67  ? 93.615  85.094  -76.396 1.00 42.04  ? 67  SER L2 C   1 
ATOM 4857 O O   . SER B 2 67  ? 93.450  85.095  -77.617 1.00 42.69  ? 67  SER L2 O   1 
ATOM 4858 C CB  . SER B 2 67  ? 91.718  86.545  -75.648 1.00 44.20  ? 67  SER L2 CB  1 
ATOM 4859 O OG  . SER B 2 67  ? 91.014  85.318  -75.644 1.00 47.70  ? 67  SER L2 OG  1 
ATOM 4860 N N   . GLY B 2 68  ? 94.113  84.065  -75.727 1.00 43.06  ? 68  GLY L2 N   1 
ATOM 4861 C CA  . GLY B 2 68  ? 94.564  82.883  -76.425 1.00 43.60  ? 68  GLY L2 CA  1 
ATOM 4862 C C   . GLY B 2 68  ? 96.043  82.637  -76.239 1.00 44.62  ? 68  GLY L2 C   1 
ATOM 4863 O O   . GLY B 2 68  ? 96.483  82.264  -75.152 1.00 44.94  ? 68  GLY L2 O   1 
ATOM 4864 N N   . THR B 2 69  ? 96.827  82.827  -77.292 1.00 44.96  ? 69  THR L2 N   1 
ATOM 4865 C CA  . THR B 2 69  ? 98.267  82.720  -77.179 1.00 44.50  ? 69  THR L2 CA  1 
ATOM 4866 C C   . THR B 2 69  ? 98.982  84.043  -77.368 1.00 42.75  ? 69  THR L2 C   1 
ATOM 4867 O O   . THR B 2 69  ? 100.069 84.217  -76.811 1.00 42.74  ? 69  THR L2 O   1 
ATOM 4868 C CB  . THR B 2 69  ? 98.822  81.708  -78.193 1.00 44.89  ? 69  THR L2 CB  1 
ATOM 4869 O OG1 . THR B 2 69  ? 98.166  81.875  -79.455 1.00 46.64  ? 69  THR L2 OG1 1 
ATOM 4870 C CG2 . THR B 2 69  ? 98.616  80.285  -77.697 1.00 45.08  ? 69  THR L2 CG2 1 
ATOM 4871 N N   . ASP B 2 70  ? 98.407  84.984  -78.106 1.00 42.67  ? 70  ASP L2 N   1 
ATOM 4872 C CA  . ASP B 2 70  ? 99.056  86.250  -78.412 1.00 41.93  ? 70  ASP L2 CA  1 
ATOM 4873 C C   . ASP B 2 70  ? 98.499  87.335  -77.509 1.00 40.80  ? 70  ASP L2 C   1 
ATOM 4874 O O   . ASP B 2 70  ? 97.284  87.552  -77.466 1.00 41.37  ? 70  ASP L2 O   1 
ATOM 4875 C CB  . ASP B 2 70  ? 98.848  86.635  -79.876 1.00 44.60  ? 70  ASP L2 CB  1 
ATOM 4876 C CG  . ASP B 2 70  ? 99.261  85.537  -80.827 1.00 47.00  ? 70  ASP L2 CG  1 
ATOM 4877 O OD1 . ASP B 2 70  ? 100.435 85.124  -80.787 1.00 49.31  ? 70  ASP L2 OD1 1 
ATOM 4878 O OD2 . ASP B 2 70  ? 98.407  85.086  -81.617 1.00 51.01  ? 70  ASP L2 OD2 1 
ATOM 4879 N N   . PHE B 2 71  ? 99.390  88.018  -76.803 1.00 39.08  ? 71  PHE L2 N   1 
ATOM 4880 C CA  . PHE B 2 71  ? 99.025  89.094  -75.901 1.00 37.10  ? 71  PHE L2 CA  1 
ATOM 4881 C C   . PHE B 2 71  ? 99.893  90.295  -76.212 1.00 36.50  ? 71  PHE L2 C   1 
ATOM 4882 O O   . PHE B 2 71  ? 101.010 90.161  -76.707 1.00 35.18  ? 71  PHE L2 O   1 
ATOM 4883 C CB  . PHE B 2 71  ? 99.202  88.684  -74.438 1.00 36.57  ? 71  PHE L2 CB  1 
ATOM 4884 C CG  . PHE B 2 71  ? 98.274  87.604  -74.009 1.00 36.87  ? 71  PHE L2 CG  1 
ATOM 4885 C CD1 . PHE B 2 71  ? 98.604  86.279  -74.190 1.00 36.31  ? 71  PHE L2 CD1 1 
ATOM 4886 C CD2 . PHE B 2 71  ? 97.063  87.913  -73.437 1.00 37.38  ? 71  PHE L2 CD2 1 
ATOM 4887 C CE1 . PHE B 2 71  ? 97.739  85.293  -73.805 1.00 36.22  ? 71  PHE L2 CE1 1 
ATOM 4888 C CE2 . PHE B 2 71  ? 96.202  86.926  -73.058 1.00 35.06  ? 71  PHE L2 CE2 1 
ATOM 4889 C CZ  . PHE B 2 71  ? 96.540  85.623  -73.241 1.00 36.22  ? 71  PHE L2 CZ  1 
ATOM 4890 N N   . THR B 2 72  ? 99.379  91.477  -75.904 1.00 36.24  ? 72  THR L2 N   1 
ATOM 4891 C CA  . THR B 2 72  ? 100.144 92.684  -76.148 1.00 37.87  ? 72  THR L2 CA  1 
ATOM 4892 C C   . THR B 2 72  ? 100.010 93.609  -74.951 1.00 36.76  ? 72  THR L2 C   1 
ATOM 4893 O O   . THR B 2 72  ? 99.041  93.544  -74.194 1.00 36.55  ? 72  THR L2 O   1 
ATOM 4894 C CB  . THR B 2 72  ? 99.709  93.369  -77.451 1.00 39.13  ? 72  THR L2 CB  1 
ATOM 4895 O OG1 . THR B 2 72  ? 100.699 94.324  -77.849 1.00 43.75  ? 72  THR L2 OG1 1 
ATOM 4896 C CG2 . THR B 2 72  ? 98.371  94.063  -77.309 1.00 40.42  ? 72  THR L2 CG2 1 
ATOM 4897 N N   . PHE B 2 73  ? 101.025 94.438  -74.762 1.00 35.31  ? 73  PHE L2 N   1 
ATOM 4898 C CA  . PHE B 2 73  ? 101.044 95.426  -73.700 1.00 34.01  ? 73  PHE L2 CA  1 
ATOM 4899 C C   . PHE B 2 73  ? 101.362 96.770  -74.322 1.00 33.87  ? 73  PHE L2 C   1 
ATOM 4900 O O   . PHE B 2 73  ? 102.313 96.881  -75.094 1.00 32.52  ? 73  PHE L2 O   1 
ATOM 4901 C CB  . PHE B 2 73  ? 102.070 95.080  -72.638 1.00 34.67  ? 73  PHE L2 CB  1 
ATOM 4902 C CG  . PHE B 2 73  ? 102.004 95.966  -71.445 1.00 33.71  ? 73  PHE L2 CG  1 
ATOM 4903 C CD1 . PHE B 2 73  ? 100.784 96.353  -70.935 1.00 31.56  ? 73  PHE L2 CD1 1 
ATOM 4904 C CD2 . PHE B 2 73  ? 103.155 96.401  -70.826 1.00 34.46  ? 73  PHE L2 CD2 1 
ATOM 4905 C CE1 . PHE B 2 73  ? 100.714 97.163  -69.841 1.00 32.29  ? 73  PHE L2 CE1 1 
ATOM 4906 C CE2 . PHE B 2 73  ? 103.085 97.210  -69.728 1.00 32.42  ? 73  PHE L2 CE2 1 
ATOM 4907 C CZ  . PHE B 2 73  ? 101.863 97.588  -69.238 1.00 32.10  ? 73  PHE L2 CZ  1 
ATOM 4908 N N   . THR B 2 74  ? 100.581 97.786  -73.986 1.00 33.47  ? 74  THR L2 N   1 
ATOM 4909 C CA  . THR B 2 74  ? 100.650 99.056  -74.687 1.00 34.39  ? 74  THR L2 CA  1 
ATOM 4910 C C   . THR B 2 74  ? 100.801 100.198 -73.697 1.00 34.79  ? 74  THR L2 C   1 
ATOM 4911 O O   . THR B 2 74  ? 100.032 100.299 -72.740 1.00 34.51  ? 74  THR L2 O   1 
ATOM 4912 C CB  . THR B 2 74  ? 99.399  99.261  -75.541 1.00 33.94  ? 74  THR L2 CB  1 
ATOM 4913 O OG1 . THR B 2 74  ? 99.043  98.020  -76.161 1.00 34.33  ? 74  THR L2 OG1 1 
ATOM 4914 C CG2 . THR B 2 74  ? 99.647  100.302 -76.615 1.00 33.05  ? 74  THR L2 CG2 1 
ATOM 4915 N N   . ILE B 2 75  ? 101.789 101.054 -73.933 1.00 35.06  ? 75  ILE L2 N   1 
ATOM 4916 C CA  . ILE B 2 75  ? 101.911 102.327 -73.234 1.00 35.93  ? 75  ILE L2 CA  1 
ATOM 4917 C C   . ILE B 2 75  ? 101.666 103.435 -74.245 1.00 37.87  ? 75  ILE L2 C   1 
ATOM 4918 O O   . ILE B 2 75  ? 102.439 103.594 -75.197 1.00 39.82  ? 75  ILE L2 O   1 
ATOM 4919 C CB  . ILE B 2 75  ? 103.289 102.478 -72.574 1.00 34.08  ? 75  ILE L2 CB  1 
ATOM 4920 C CG1 . ILE B 2 75  ? 103.620 101.238 -71.758 1.00 33.15  ? 75  ILE L2 CG1 1 
ATOM 4921 C CG2 . ILE B 2 75  ? 103.301 103.687 -71.672 1.00 32.47  ? 75  ILE L2 CG2 1 
ATOM 4922 C CD1 . ILE B 2 75  ? 105.022 101.219 -71.261 1.00 36.50  ? 75  ILE L2 CD1 1 
ATOM 4923 N N   . SER B 2 76  ? 100.593 104.199 -74.037 1.00 38.75  ? 76  SER L2 N   1 
ATOM 4924 C CA  . SER B 2 76  ? 100.135 105.156 -75.039 1.00 39.86  ? 76  SER L2 CA  1 
ATOM 4925 C C   . SER B 2 76  ? 101.074 106.349 -75.168 1.00 39.90  ? 76  SER L2 C   1 
ATOM 4926 O O   . SER B 2 76  ? 101.220 106.909 -76.261 1.00 40.00  ? 76  SER L2 O   1 
ATOM 4927 C CB  . SER B 2 76  ? 98.728  105.638 -74.694 1.00 39.65  ? 76  SER L2 CB  1 
ATOM 4928 O OG  . SER B 2 76  ? 98.780  106.773 -73.849 1.00 41.52  ? 76  SER L2 OG  1 
ATOM 4929 N N   . SER B 2 77  ? 101.708 106.760 -74.074 1.00 40.13  ? 77  SER L2 N   1 
ATOM 4930 C CA  . SER B 2 77  ? 102.652 107.874 -74.079 1.00 40.24  ? 77  SER L2 CA  1 
ATOM 4931 C C   . SER B 2 77  ? 103.780 107.523 -73.117 1.00 39.47  ? 77  SER L2 C   1 
ATOM 4932 O O   . SER B 2 77  ? 103.651 107.743 -71.910 1.00 37.92  ? 77  SER L2 O   1 
ATOM 4933 C CB  . SER B 2 77  ? 101.966 109.177 -73.683 1.00 41.39  ? 77  SER L2 CB  1 
ATOM 4934 O OG  . SER B 2 77  ? 102.704 110.303 -74.125 1.00 42.63  ? 77  SER L2 OG  1 
ATOM 4935 N N   . VAL B 2 78  ? 104.867 106.974 -73.654 1.00 39.43  ? 78  VAL L2 N   1 
ATOM 4936 C CA  . VAL B 2 78  ? 105.986 106.499 -72.849 1.00 38.46  ? 78  VAL L2 CA  1 
ATOM 4937 C C   . VAL B 2 78  ? 106.652 107.677 -72.161 1.00 38.55  ? 78  VAL L2 C   1 
ATOM 4938 O O   . VAL B 2 78  ? 106.982 108.682 -72.798 1.00 39.45  ? 78  VAL L2 O   1 
ATOM 4939 C CB  . VAL B 2 78  ? 106.992 105.734 -73.723 1.00 37.56  ? 78  VAL L2 CB  1 
ATOM 4940 C CG1 . VAL B 2 78  ? 107.988 104.992 -72.861 1.00 37.29  ? 78  VAL L2 CG1 1 
ATOM 4941 C CG2 . VAL B 2 78  ? 106.274 104.783 -74.637 1.00 35.84  ? 78  VAL L2 CG2 1 
ATOM 4942 N N   . GLN B 2 79  ? 106.840 107.565 -70.852 1.00 39.14  ? 79  GLN L2 N   1 
ATOM 4943 C CA  . GLN B 2 79  ? 107.398 108.643 -70.057 1.00 40.85  ? 79  GLN L2 CA  1 
ATOM 4944 C C   . GLN B 2 79  ? 108.713 108.191 -69.445 1.00 40.40  ? 79  GLN L2 C   1 
ATOM 4945 O O   . GLN B 2 79  ? 109.229 107.117 -69.756 1.00 39.51  ? 79  GLN L2 O   1 
ATOM 4946 C CB  . GLN B 2 79  ? 106.428 109.093 -68.963 1.00 41.12  ? 79  GLN L2 CB  1 
ATOM 4947 C CG  . GLN B 2 79  ? 105.093 109.558 -69.477 1.00 44.25  ? 79  GLN L2 CG  1 
ATOM 4948 C CD  . GLN B 2 79  ? 104.195 110.025 -68.359 1.00 45.33  ? 79  GLN L2 CD  1 
ATOM 4949 O OE1 . GLN B 2 79  ? 104.549 109.922 -67.184 1.00 45.40  ? 79  GLN L2 OE1 1 
ATOM 4950 N NE2 . GLN B 2 79  ? 103.026 110.541 -68.713 1.00 45.46  ? 79  GLN L2 NE2 1 
ATOM 4951 N N   . ALA B 2 80  ? 109.252 109.034 -68.562 1.00 40.01  ? 80  ALA L2 N   1 
ATOM 4952 C CA  . ALA B 2 80  ? 110.556 108.759 -67.970 1.00 39.58  ? 80  ALA L2 CA  1 
ATOM 4953 C C   . ALA B 2 80  ? 110.505 107.596 -66.994 1.00 38.86  ? 80  ALA L2 C   1 
ATOM 4954 O O   . ALA B 2 80  ? 111.454 106.807 -66.924 1.00 39.89  ? 80  ALA L2 O   1 
ATOM 4955 C CB  . ALA B 2 80  ? 111.083 110.007 -67.264 1.00 41.31  ? 80  ALA L2 CB  1 
ATOM 4956 N N   . GLU B 2 81  ? 109.412 107.466 -66.241 1.00 37.19  ? 81  GLU L2 N   1 
ATOM 4957 C CA  . GLU B 2 81  ? 109.270 106.406 -65.250 1.00 36.85  ? 81  GLU L2 CA  1 
ATOM 4958 C C   . GLU B 2 81  ? 108.570 105.172 -65.808 1.00 34.83  ? 81  GLU L2 C   1 
ATOM 4959 O O   . GLU B 2 81  ? 108.151 104.299 -65.037 1.00 36.80  ? 81  GLU L2 O   1 
ATOM 4960 C CB  . GLU B 2 81  ? 108.542 106.940 -64.015 1.00 37.86  ? 81  GLU L2 CB  1 
ATOM 4961 C CG  . GLU B 2 81  ? 107.072 107.288 -64.221 1.00 41.61  ? 81  GLU L2 CG  1 
ATOM 4962 C CD  . GLU B 2 81  ? 106.857 108.702 -64.718 1.00 42.52  ? 81  GLU L2 CD  1 
ATOM 4963 O OE1 . GLU B 2 81  ? 106.191 109.482 -64.008 1.00 43.64  ? 81  GLU L2 OE1 1 
ATOM 4964 O OE2 . GLU B 2 81  ? 107.342 109.033 -65.818 1.00 44.32  ? 81  GLU L2 OE2 1 
ATOM 4965 N N   . ASP B 2 82  ? 108.440 105.071 -67.128 1.00 31.37  ? 82  ASP L2 N   1 
ATOM 4966 C CA  . ASP B 2 82  ? 107.906 103.878 -67.764 1.00 29.21  ? 82  ASP L2 CA  1 
ATOM 4967 C C   . ASP B 2 82  ? 108.984 102.986 -68.353 1.00 27.64  ? 82  ASP L2 C   1 
ATOM 4968 O O   . ASP B 2 82  ? 108.666 101.895 -68.830 1.00 25.59  ? 82  ASP L2 O   1 
ATOM 4969 C CB  . ASP B 2 82  ? 106.911 104.254 -68.865 1.00 27.20  ? 82  ASP L2 CB  1 
ATOM 4970 C CG  . ASP B 2 82  ? 105.691 104.958 -68.328 1.00 29.16  ? 82  ASP L2 CG  1 
ATOM 4971 O OD1 . ASP B 2 82  ? 104.800 105.294 -69.131 1.00 28.82  ? 82  ASP L2 OD1 1 
ATOM 4972 O OD2 . ASP B 2 82  ? 105.617 105.177 -67.103 1.00 28.63  ? 82  ASP L2 OD2 1 
ATOM 4973 N N   . LEU B 2 83  ? 110.245 103.418 -68.351 1.00 27.43  ? 83  LEU L2 N   1 
ATOM 4974 C CA  . LEU B 2 83  ? 111.345 102.607 -68.869 1.00 28.04  ? 83  LEU L2 CA  1 
ATOM 4975 C C   . LEU B 2 83  ? 111.826 101.675 -67.763 1.00 27.74  ? 83  LEU L2 C   1 
ATOM 4976 O O   . LEU B 2 83  ? 112.663 102.021 -66.928 1.00 29.92  ? 83  LEU L2 O   1 
ATOM 4977 C CB  . LEU B 2 83  ? 112.486 103.477 -69.381 1.00 28.61  ? 83  LEU L2 CB  1 
ATOM 4978 C CG  . LEU B 2 83  ? 112.467 104.005 -70.815 1.00 30.60  ? 83  LEU L2 CG  1 
ATOM 4979 C CD1 . LEU B 2 83  ? 111.474 105.118 -71.011 1.00 35.12  ? 83  LEU L2 CD1 1 
ATOM 4980 C CD2 . LEU B 2 83  ? 113.857 104.468 -71.196 1.00 30.80  ? 83  LEU L2 CD2 1 
ATOM 4981 N N   . ALA B 2 84  ? 111.281 100.463 -67.764 1.00 26.08  ? 84  ALA L2 N   1 
ATOM 4982 C CA  . ALA B 2 84  ? 111.678 99.449  -66.803 1.00 24.65  ? 84  ALA L2 CA  1 
ATOM 4983 C C   . ALA B 2 84  ? 111.702 98.104  -67.511 1.00 24.62  ? 84  ALA L2 C   1 
ATOM 4984 O O   . ALA B 2 84  ? 111.612 98.019  -68.737 1.00 24.43  ? 84  ALA L2 O   1 
ATOM 4985 C CB  . ALA B 2 84  ? 110.739 99.447  -65.591 1.00 25.47  ? 84  ALA L2 CB  1 
ATOM 4986 N N   . LEU B 2 85  ? 111.846 97.050  -66.719 1.00 23.31  ? 85  LEU L2 N   1 
ATOM 4987 C CA  . LEU B 2 85  ? 111.748 95.672  -67.175 1.00 23.54  ? 85  LEU L2 CA  1 
ATOM 4988 C C   . LEU B 2 85  ? 110.296 95.237  -67.052 1.00 24.98  ? 85  LEU L2 C   1 
ATOM 4989 O O   . LEU B 2 85  ? 109.705 95.347  -65.973 1.00 23.64  ? 85  LEU L2 O   1 
ATOM 4990 C CB  . LEU B 2 85  ? 112.660 94.777  -66.337 1.00 23.35  ? 85  LEU L2 CB  1 
ATOM 4991 C CG  . LEU B 2 85  ? 113.103 93.420  -66.857 1.00 27.70  ? 85  LEU L2 CG  1 
ATOM 4992 C CD1 . LEU B 2 85  ? 113.551 93.533  -68.277 1.00 30.77  ? 85  LEU L2 CD1 1 
ATOM 4993 C CD2 . LEU B 2 85  ? 114.228 92.890  -65.996 1.00 27.15  ? 85  LEU L2 CD2 1 
ATOM 4994 N N   . TYR B 2 86  ? 109.713 94.776  -68.151 1.00 23.65  ? 86  TYR L2 N   1 
ATOM 4995 C CA  . TYR B 2 86  ? 108.299 94.427  -68.192 1.00 22.97  ? 86  TYR L2 CA  1 
ATOM 4996 C C   . TYR B 2 86  ? 108.141 92.918  -68.281 1.00 22.76  ? 86  TYR L2 C   1 
ATOM 4997 O O   . TYR B 2 86  ? 108.680 92.286  -69.194 1.00 24.65  ? 86  TYR L2 O   1 
ATOM 4998 C CB  . TYR B 2 86  ? 107.606 95.117  -69.358 1.00 21.98  ? 86  TYR L2 CB  1 
ATOM 4999 C CG  . TYR B 2 86  ? 107.254 96.530  -69.016 1.00 22.18  ? 86  TYR L2 CG  1 
ATOM 5000 C CD1 . TYR B 2 86  ? 107.986 97.585  -69.515 1.00 20.28  ? 86  TYR L2 CD1 1 
ATOM 5001 C CD2 . TYR B 2 86  ? 106.210 96.804  -68.157 1.00 21.06  ? 86  TYR L2 CD2 1 
ATOM 5002 C CE1 . TYR B 2 86  ? 107.671 98.873  -69.192 1.00 20.44  ? 86  TYR L2 CE1 1 
ATOM 5003 C CE2 . TYR B 2 86  ? 105.893 98.093  -67.827 1.00 22.25  ? 86  TYR L2 CE2 1 
ATOM 5004 C CZ  . TYR B 2 86  ? 106.626 99.121  -68.350 1.00 20.76  ? 86  TYR L2 CZ  1 
ATOM 5005 O OH  . TYR B 2 86  ? 106.303 100.411 -68.020 1.00 21.40  ? 86  TYR L2 OH  1 
ATOM 5006 N N   . TYR B 2 87  ? 107.393 92.351  -67.342 1.00 24.47  ? 87  TYR L2 N   1 
ATOM 5007 C CA  . TYR B 2 87  ? 107.303 90.911  -67.171 1.00 24.02  ? 87  TYR L2 CA  1 
ATOM 5008 C C   . TYR B 2 87  ? 105.896 90.427  -67.472 1.00 26.15  ? 87  TYR L2 C   1 
ATOM 5009 O O   . TYR B 2 87  ? 104.929 91.176  -67.322 1.00 22.98  ? 87  TYR L2 O   1 
ATOM 5010 C CB  . TYR B 2 87  ? 107.701 90.515  -65.759 1.00 25.34  ? 87  TYR L2 CB  1 
ATOM 5011 C CG  . TYR B 2 87  ? 109.179 90.319  -65.584 1.00 26.21  ? 87  TYR L2 CG  1 
ATOM 5012 C CD1 . TYR B 2 87  ? 109.809 89.191  -66.083 1.00 25.95  ? 87  TYR L2 CD1 1 
ATOM 5013 C CD2 . TYR B 2 87  ? 109.942 91.256  -64.912 1.00 27.12  ? 87  TYR L2 CD2 1 
ATOM 5014 C CE1 . TYR B 2 87  ? 111.161 89.002  -65.919 1.00 27.60  ? 87  TYR L2 CE1 1 
ATOM 5015 C CE2 . TYR B 2 87  ? 111.290 91.074  -64.742 1.00 26.91  ? 87  TYR L2 CE2 1 
ATOM 5016 C CZ  . TYR B 2 87  ? 111.894 89.947  -65.244 1.00 28.30  ? 87  TYR L2 CZ  1 
ATOM 5017 O OH  . TYR B 2 87  ? 113.242 89.760  -65.076 1.00 29.77  ? 87  TYR L2 OH  1 
ATOM 5018 N N   . CYS B 2 88  ? 105.795 89.178  -67.889 1.00 27.93  ? 88  CYS L2 N   1 
ATOM 5019 C CA  . CYS B 2 88  ? 104.547 88.582  -68.329 1.00 32.20  ? 88  CYS L2 CA  1 
ATOM 5020 C C   . CYS B 2 88  ? 104.294 87.291  -67.569 1.00 30.23  ? 88  CYS L2 C   1 
ATOM 5021 O O   . CYS B 2 88  ? 105.038 86.324  -67.718 1.00 30.55  ? 88  CYS L2 O   1 
ATOM 5022 C CB  . CYS B 2 88  ? 104.617 88.303  -69.826 1.00 35.88  ? 88  CYS L2 CB  1 
ATOM 5023 S SG  . CYS B 2 88  ? 103.471 87.099  -70.442 1.00 51.08  ? 88  CYS L2 SG  1 
ATOM 5024 N N   . GLN B 2 89  ? 103.238 87.269  -66.766 1.00 30.28  ? 89  GLN L2 N   1 
ATOM 5025 C CA  . GLN B 2 89  ? 102.984 86.113  -65.920 1.00 28.82  ? 89  GLN L2 CA  1 
ATOM 5026 C C   . GLN B 2 89  ? 101.581 85.600  -66.163 1.00 28.69  ? 89  GLN L2 C   1 
ATOM 5027 O O   . GLN B 2 89  ? 100.643 86.384  -66.269 1.00 27.21  ? 89  GLN L2 O   1 
ATOM 5028 C CB  . GLN B 2 89  ? 103.197 86.463  -64.448 1.00 30.23  ? 89  GLN L2 CB  1 
ATOM 5029 C CG  . GLN B 2 89  ? 103.023 85.322  -63.464 1.00 29.49  ? 89  GLN L2 CG  1 
ATOM 5030 C CD  . GLN B 2 89  ? 101.756 85.428  -62.669 1.00 30.71  ? 89  GLN L2 CD  1 
ATOM 5031 O OE1 . GLN B 2 89  ? 101.286 86.523  -62.392 1.00 30.76  ? 89  GLN L2 OE1 1 
ATOM 5032 N NE2 . GLN B 2 89  ? 101.206 84.297  -62.275 1.00 31.46  ? 89  GLN L2 NE2 1 
ATOM 5033 N N   . GLN B 2 90  ? 101.450 84.285  -66.269 1.00 29.31  ? 90  GLN L2 N   1 
ATOM 5034 C CA  . GLN B 2 90  ? 100.165 83.652  -66.505 1.00 30.55  ? 90  GLN L2 CA  1 
ATOM 5035 C C   . GLN B 2 90  ? 99.593  83.100  -65.206 1.00 31.14  ? 90  GLN L2 C   1 
ATOM 5036 O O   . GLN B 2 90  ? 100.276 82.427  -64.434 1.00 29.91  ? 90  GLN L2 O   1 
ATOM 5037 C CB  . GLN B 2 90  ? 100.289 82.537  -67.539 1.00 28.95  ? 90  GLN L2 CB  1 
ATOM 5038 C CG  . GLN B 2 90  ? 101.405 81.555  -67.295 1.00 27.47  ? 90  GLN L2 CG  1 
ATOM 5039 C CD  . GLN B 2 90  ? 100.905 80.314  -66.627 1.00 29.85  ? 90  GLN L2 CD  1 
ATOM 5040 O OE1 . GLN B 2 90  ? 99.725  80.039  -66.656 1.00 26.91  ? 90  GLN L2 OE1 1 
ATOM 5041 N NE2 . GLN B 2 90  ? 101.796 79.549  -66.033 1.00 26.72  ? 90  GLN L2 NE2 1 
ATOM 5042 N N   . HIS B 2 91  ? 98.328  83.409  -64.958 1.00 32.95  ? 91  HIS L2 N   1 
ATOM 5043 C CA  . HIS B 2 91  ? 97.663  82.819  -63.812 1.00 35.69  ? 91  HIS L2 CA  1 
ATOM 5044 C C   . HIS B 2 91  ? 96.598  81.867  -64.303 1.00 37.46  ? 91  HIS L2 C   1 
ATOM 5045 O O   . HIS B 2 91  ? 95.455  81.898  -63.848 1.00 37.84  ? 91  HIS L2 O   1 
ATOM 5046 C CB  . HIS B 2 91  ? 97.109  83.886  -62.876 1.00 35.31  ? 91  HIS L2 CB  1 
ATOM 5047 C CG  . HIS B 2 91  ? 96.392  84.997  -63.563 1.00 36.37  ? 91  HIS L2 CG  1 
ATOM 5048 N ND1 . HIS B 2 91  ? 95.065  84.931  -63.920 1.00 38.40  ? 91  HIS L2 ND1 1 
ATOM 5049 C CD2 . HIS B 2 91  ? 96.810  86.234  -63.903 1.00 37.17  ? 91  HIS L2 CD2 1 
ATOM 5050 C CE1 . HIS B 2 91  ? 94.707  86.071  -64.481 1.00 37.35  ? 91  HIS L2 CE1 1 
ATOM 5051 N NE2 . HIS B 2 91  ? 95.748  86.878  -64.481 1.00 37.39  ? 91  HIS L2 NE2 1 
ATOM 5052 N N   . TYR B 2 92  ? 96.983  81.037  -65.266 1.00 38.51  ? 92  TYR L2 N   1 
ATOM 5053 C CA  . TYR B 2 92  ? 96.130  79.994  -65.810 1.00 40.39  ? 92  TYR L2 CA  1 
ATOM 5054 C C   . TYR B 2 92  ? 96.205  78.718  -64.976 1.00 39.79  ? 92  TYR L2 C   1 
ATOM 5055 O O   . TYR B 2 92  ? 95.225  78.329  -64.337 1.00 39.64  ? 92  TYR L2 O   1 
ATOM 5056 C CB  . TYR B 2 92  ? 96.550  79.741  -67.252 1.00 42.16  ? 92  TYR L2 CB  1 
ATOM 5057 C CG  . TYR B 2 92  ? 95.657  78.885  -68.094 1.00 43.91  ? 92  TYR L2 CG  1 
ATOM 5058 C CD1 . TYR B 2 92  ? 94.400  79.301  -68.463 1.00 44.64  ? 92  TYR L2 CD1 1 
ATOM 5059 C CD2 . TYR B 2 92  ? 96.097  77.662  -68.558 1.00 45.45  ? 92  TYR L2 CD2 1 
ATOM 5060 C CE1 . TYR B 2 92  ? 93.599  78.505  -69.250 1.00 46.04  ? 92  TYR L2 CE1 1 
ATOM 5061 C CE2 . TYR B 2 92  ? 95.309  76.866  -69.336 1.00 46.69  ? 92  TYR L2 CE2 1 
ATOM 5062 C CZ  . TYR B 2 92  ? 94.063  77.293  -69.681 1.00 46.23  ? 92  TYR L2 CZ  1 
ATOM 5063 O OH  . TYR B 2 92  ? 93.268  76.498  -70.465 1.00 47.60  ? 92  TYR L2 OH  1 
ATOM 5064 N N   . THR B 2 93  ? 97.366  78.055  -64.957 1.00 39.21  ? 93  THR L2 N   1 
ATOM 5065 C CA  . THR B 2 93  ? 97.561  76.837  -64.174 1.00 39.86  ? 93  THR L2 CA  1 
ATOM 5066 C C   . THR B 2 93  ? 98.901  76.867  -63.463 1.00 39.47  ? 93  THR L2 C   1 
ATOM 5067 O O   . THR B 2 93  ? 99.813  77.602  -63.836 1.00 39.22  ? 93  THR L2 O   1 
ATOM 5068 C CB  . THR B 2 93  ? 97.527  75.536  -65.000 1.00 40.22  ? 93  THR L2 CB  1 
ATOM 5069 O OG1 . THR B 2 93  ? 98.696  75.448  -65.819 1.00 42.64  ? 93  THR L2 OG1 1 
ATOM 5070 C CG2 . THR B 2 93  ? 96.280  75.388  -65.838 1.00 38.60  ? 93  THR L2 CG2 1 
ATOM 5071 N N   . THR B 2 94  ? 99.009  76.027  -62.457 1.00 38.88  ? 94  THR L2 N   1 
ATOM 5072 C CA  . THR B 2 94  ? 100.178 75.778  -61.629 1.00 38.70  ? 94  THR L2 CA  1 
ATOM 5073 C C   . THR B 2 94  ? 101.155 74.861  -62.363 1.00 38.76  ? 94  THR L2 C   1 
ATOM 5074 O O   . THR B 2 94  ? 100.752 73.810  -62.867 1.00 39.56  ? 94  THR L2 O   1 
ATOM 5075 C CB  . THR B 2 94  ? 99.743  75.145  -60.314 1.00 38.87  ? 94  THR L2 CB  1 
ATOM 5076 O OG1 . THR B 2 94  ? 99.081  76.128  -59.517 1.00 38.10  ? 94  THR L2 OG1 1 
ATOM 5077 C CG2 . THR B 2 94  ? 100.903 74.572  -59.537 1.00 38.91  ? 94  THR L2 CG2 1 
ATOM 5078 N N   . PRO B 2 95  ? 102.451 75.220  -62.436 1.00 37.95  ? 95  PRO L2 N   1 
ATOM 5079 C CA  . PRO B 2 95  ? 103.099 76.382  -61.820 1.00 37.46  ? 95  PRO L2 CA  1 
ATOM 5080 C C   . PRO B 2 95  ? 102.944 77.662  -62.609 1.00 37.00  ? 95  PRO L2 C   1 
ATOM 5081 O O   . PRO B 2 95  ? 102.949 77.628  -63.833 1.00 37.68  ? 95  PRO L2 O   1 
ATOM 5082 C CB  . PRO B 2 95  ? 104.560 75.964  -61.759 1.00 36.85  ? 95  PRO L2 CB  1 
ATOM 5083 C CG  . PRO B 2 95  ? 104.725 75.042  -62.857 1.00 37.87  ? 95  PRO L2 CG  1 
ATOM 5084 C CD  . PRO B 2 95  ? 103.439 74.313  -63.034 1.00 36.77  ? 95  PRO L2 CD  1 
ATOM 5085 N N   . TRP B 2 96  ? 102.757 78.768  -61.898 1.00 35.96  ? 96  TRP L2 N   1 
ATOM 5086 C CA  . TRP B 2 96  ? 102.719 80.063  -62.545 1.00 35.99  ? 96  TRP L2 CA  1 
ATOM 5087 C C   . TRP B 2 96  ? 104.098 80.382  -63.082 1.00 33.29  ? 96  TRP L2 C   1 
ATOM 5088 O O   . TRP B 2 96  ? 105.079 80.396  -62.337 1.00 33.75  ? 96  TRP L2 O   1 
ATOM 5089 C CB  . TRP B 2 96  ? 102.272 81.148  -61.578 1.00 36.96  ? 96  TRP L2 CB  1 
ATOM 5090 C CG  . TRP B 2 96  ? 101.257 80.733  -60.586 1.00 40.53  ? 96  TRP L2 CG  1 
ATOM 5091 C CD1 . TRP B 2 96  ? 101.406 80.717  -59.247 1.00 40.02  ? 96  TRP L2 CD1 1 
ATOM 5092 C CD2 . TRP B 2 96  ? 99.920  80.305  -60.847 1.00 41.56  ? 96  TRP L2 CD2 1 
ATOM 5093 N NE1 . TRP B 2 96  ? 100.255 80.296  -58.650 1.00 41.91  ? 96  TRP L2 NE1 1 
ATOM 5094 C CE2 . TRP B 2 96  ? 99.326  80.035  -59.616 1.00 42.26  ? 96  TRP L2 CE2 1 
ATOM 5095 C CE3 . TRP B 2 96  ? 99.171  80.118  -62.004 1.00 42.71  ? 96  TRP L2 CE3 1 
ATOM 5096 C CZ2 . TRP B 2 96  ? 98.023  79.585  -59.507 1.00 43.62  ? 96  TRP L2 CZ2 1 
ATOM 5097 C CZ3 . TRP B 2 96  ? 97.876  79.679  -61.889 1.00 44.28  ? 96  TRP L2 CZ3 1 
ATOM 5098 C CH2 . TRP B 2 96  ? 97.314  79.417  -60.653 1.00 44.53  ? 96  TRP L2 CH2 1 
ATOM 5099 N N   . THR B 2 97  ? 104.174 80.606  -64.381 1.00 32.93  ? 97  THR L2 N   1 
ATOM 5100 C CA  . THR B 2 97  ? 105.426 80.865  -65.057 1.00 32.09  ? 97  THR L2 CA  1 
ATOM 5101 C C   . THR B 2 97  ? 105.439 82.305  -65.523 1.00 30.46  ? 97  THR L2 C   1 
ATOM 5102 O O   . THR B 2 97  ? 104.412 82.841  -65.937 1.00 30.54  ? 97  THR L2 O   1 
ATOM 5103 C CB  . THR B 2 97  ? 105.606 79.930  -66.234 1.00 32.22  ? 97  THR L2 CB  1 
ATOM 5104 O OG1 . THR B 2 97  ? 104.548 80.143  -67.167 1.00 35.58  ? 97  THR L2 OG1 1 
ATOM 5105 C CG2 . THR B 2 97  ? 105.557 78.501  -65.761 1.00 31.62  ? 97  THR L2 CG2 1 
ATOM 5106 N N   . PHE B 2 98  ? 106.601 82.929  -65.422 1.00 28.81  ? 98  PHE L2 N   1 
ATOM 5107 C CA  . PHE B 2 98  ? 106.793 84.308  -65.823 1.00 27.76  ? 98  PHE L2 CA  1 
ATOM 5108 C C   . PHE B 2 98  ? 107.414 84.342  -67.211 1.00 26.64  ? 98  PHE L2 C   1 
ATOM 5109 O O   . PHE B 2 98  ? 108.010 83.367  -67.673 1.00 28.15  ? 98  PHE L2 O   1 
ATOM 5110 C CB  . PHE B 2 98  ? 107.684 85.051  -64.824 1.00 26.55  ? 98  PHE L2 CB  1 
ATOM 5111 C CG  . PHE B 2 98  ? 107.053 85.277  -63.479 1.00 25.58  ? 98  PHE L2 CG  1 
ATOM 5112 C CD1 . PHE B 2 98  ? 107.035 84.277  -62.528 1.00 26.15  ? 98  PHE L2 CD1 1 
ATOM 5113 C CD2 . PHE B 2 98  ? 106.519 86.504  -63.155 1.00 24.45  ? 98  PHE L2 CD2 1 
ATOM 5114 C CE1 . PHE B 2 98  ? 106.468 84.483  -61.298 1.00 24.52  ? 98  PHE L2 CE1 1 
ATOM 5115 C CE2 . PHE B 2 98  ? 105.956 86.717  -61.920 1.00 23.73  ? 98  PHE L2 CE2 1 
ATOM 5116 C CZ  . PHE B 2 98  ? 105.927 85.703  -60.997 1.00 24.10  ? 98  PHE L2 CZ  1 
ATOM 5117 N N   . GLY B 2 99  ? 107.272 85.480  -67.881 1.00 25.79  ? 99  GLY L2 N   1 
ATOM 5118 C CA  . GLY B 2 99  ? 107.930 85.712  -69.147 1.00 25.06  ? 99  GLY L2 CA  1 
ATOM 5119 C C   . GLY B 2 99  ? 109.411 85.979  -68.971 1.00 24.69  ? 99  GLY L2 C   1 
ATOM 5120 O O   . GLY B 2 99  ? 109.947 86.009  -67.862 1.00 22.36  ? 99  GLY L2 O   1 
ATOM 5121 N N   . GLY B 2 100 ? 110.081 86.183  -70.099 1.00 24.84  ? 100 GLY L2 N   1 
ATOM 5122 C CA  . GLY B 2 100 ? 111.506 86.435  -70.085 1.00 23.50  ? 100 GLY L2 CA  1 
ATOM 5123 C C   . GLY B 2 100 ? 111.855 87.828  -69.612 1.00 21.76  ? 100 GLY L2 C   1 
ATOM 5124 O O   . GLY B 2 100 ? 112.953 88.064  -69.103 1.00 22.76  ? 100 GLY L2 O   1 
ATOM 5125 N N   . GLY B 2 101 ? 110.922 88.757  -69.762 1.00 22.55  ? 101 GLY L2 N   1 
ATOM 5126 C CA  . GLY B 2 101 ? 111.182 90.133  -69.403 1.00 21.99  ? 101 GLY L2 CA  1 
ATOM 5127 C C   . GLY B 2 101 ? 111.632 90.942  -70.597 1.00 20.68  ? 101 GLY L2 C   1 
ATOM 5128 O O   . GLY B 2 101 ? 112.385 90.445  -71.435 1.00 22.34  ? 101 GLY L2 O   1 
ATOM 5129 N N   . THR B 2 102 ? 111.169 92.181  -70.692 1.00 22.85  ? 102 THR L2 N   1 
ATOM 5130 C CA  . THR B 2 102 ? 111.499 93.058  -71.805 1.00 22.42  ? 102 THR L2 CA  1 
ATOM 5131 C C   . THR B 2 102 ? 111.872 94.425  -71.259 1.00 23.51  ? 102 THR L2 C   1 
ATOM 5132 O O   . THR B 2 102 ? 111.083 95.046  -70.541 1.00 23.71  ? 102 THR L2 O   1 
ATOM 5133 C CB  . THR B 2 102 ? 110.329 93.170  -72.780 1.00 23.49  ? 102 THR L2 CB  1 
ATOM 5134 O OG1 . THR B 2 102 ? 110.230 91.963  -73.538 1.00 19.83  ? 102 THR L2 OG1 1 
ATOM 5135 C CG2 . THR B 2 102 ? 110.528 94.318  -73.728 1.00 23.73  ? 102 THR L2 CG2 1 
ATOM 5136 N N   . LYS B 2 103 ? 113.078 94.885  -71.589 1.00 24.15  ? 103 LYS L2 N   1 
ATOM 5137 C CA  . LYS B 2 103 ? 113.621 96.132  -71.071 1.00 22.62  ? 103 LYS L2 CA  1 
ATOM 5138 C C   . LYS B 2 103 ? 113.352 97.258  -72.065 1.00 22.81  ? 103 LYS L2 C   1 
ATOM 5139 O O   . LYS B 2 103 ? 113.913 97.272  -73.162 1.00 25.35  ? 103 LYS L2 O   1 
ATOM 5140 C CB  . LYS B 2 103 ? 115.116 95.984  -70.805 1.00 23.25  ? 103 LYS L2 CB  1 
ATOM 5141 C CG  . LYS B 2 103 ? 115.786 97.247  -70.314 1.00 21.40  ? 103 LYS L2 CG  1 
ATOM 5142 C CD  . LYS B 2 103 ? 115.614 97.413  -68.821 1.00 20.45  ? 103 LYS L2 CD  1 
ATOM 5143 C CE  . LYS B 2 103 ? 115.782 98.860  -68.415 1.00 23.53  ? 103 LYS L2 CE  1 
ATOM 5144 N NZ  . LYS B 2 103 ? 114.820 99.735  -69.138 1.00 16.60  ? 103 LYS L2 NZ  1 
ATOM 5145 N N   . LEU B 2 104 ? 112.505 98.205  -71.678 1.00 21.92  ? 104 LEU L2 N   1 
ATOM 5146 C CA  . LEU B 2 104 ? 112.279 99.408  -72.472 1.00 23.12  ? 104 LEU L2 CA  1 
ATOM 5147 C C   . LEU B 2 104 ? 113.477 100.330 -72.304 1.00 24.39  ? 104 LEU L2 C   1 
ATOM 5148 O O   . LEU B 2 104 ? 113.898 100.607 -71.176 1.00 20.86  ? 104 LEU L2 O   1 
ATOM 5149 C CB  . LEU B 2 104 ? 111.006 100.129 -72.040 1.00 22.46  ? 104 LEU L2 CB  1 
ATOM 5150 C CG  . LEU B 2 104 ? 109.650 99.468  -72.235 1.00 25.00  ? 104 LEU L2 CG  1 
ATOM 5151 C CD1 . LEU B 2 104 ? 108.588 100.540 -72.254 1.00 25.49  ? 104 LEU L2 CD1 1 
ATOM 5152 C CD2 . LEU B 2 104 ? 109.614 98.663  -73.509 1.00 22.91  ? 104 LEU L2 CD2 1 
ATOM 5153 N N   . GLU B 2 105 ? 114.020 100.814 -73.419 1.00 24.72  ? 105 GLU L2 N   1 
ATOM 5154 C CA  . GLU B 2 105 ? 115.206 101.652 -73.381 1.00 28.00  ? 105 GLU L2 CA  1 
ATOM 5155 C C   . GLU B 2 105 ? 115.107 102.725 -74.452 1.00 28.87  ? 105 GLU L2 C   1 
ATOM 5156 O O   . GLU B 2 105 ? 114.211 102.712 -75.299 1.00 27.29  ? 105 GLU L2 O   1 
ATOM 5157 C CB  . GLU B 2 105 ? 116.479 100.824 -73.558 1.00 26.28  ? 105 GLU L2 CB  1 
ATOM 5158 C CG  . GLU B 2 105 ? 116.369 99.746  -74.604 1.00 25.82  ? 105 GLU L2 CG  1 
ATOM 5159 C CD  . GLU B 2 105 ? 117.476 98.726  -74.483 1.00 28.77  ? 105 GLU L2 CD  1 
ATOM 5160 O OE1 . GLU B 2 105 ? 117.813 98.346  -73.343 1.00 26.82  ? 105 GLU L2 OE1 1 
ATOM 5161 O OE2 . GLU B 2 105 ? 118.020 98.315  -75.527 1.00 27.20  ? 105 GLU L2 OE2 1 
ATOM 5162 N N   . ILE B 2 106 ? 116.053 103.654 -74.402 1.00 29.84  ? 106 ILE L2 N   1 
ATOM 5163 C CA  . ILE B 2 106 ? 116.055 104.840 -75.248 1.00 28.75  ? 106 ILE L2 CA  1 
ATOM 5164 C C   . ILE B 2 106 ? 116.610 104.481 -76.620 1.00 29.14  ? 106 ILE L2 C   1 
ATOM 5165 O O   . ILE B 2 106 ? 117.640 103.805 -76.727 1.00 27.77  ? 106 ILE L2 O   1 
ATOM 5166 C CB  . ILE B 2 106 ? 116.869 105.968 -74.589 1.00 30.84  ? 106 ILE L2 CB  1 
ATOM 5167 C CG1 . ILE B 2 106 ? 116.120 106.515 -73.371 1.00 32.98  ? 106 ILE L2 CG1 1 
ATOM 5168 C CG2 . ILE B 2 106 ? 117.198 107.094 -75.573 1.00 32.15  ? 106 ILE L2 CG2 1 
ATOM 5169 C CD1 . ILE B 2 106 ? 114.899 107.342 -73.719 1.00 35.51  ? 106 ILE L2 CD1 1 
ATOM 5170 N N   . LYS B 2 107 ? 115.909 104.909 -77.671 1.00 27.86  ? 107 LYS L2 N   1 
ATOM 5171 C CA  . LYS B 2 107 ? 116.446 104.846 -79.023 1.00 27.46  ? 107 LYS L2 CA  1 
ATOM 5172 C C   . LYS B 2 107 ? 117.651 105.771 -79.153 1.00 25.49  ? 107 LYS L2 C   1 
ATOM 5173 O O   . LYS B 2 107 ? 117.502 106.996 -79.173 1.00 26.18  ? 107 LYS L2 O   1 
ATOM 5174 C CB  . LYS B 2 107 ? 115.362 105.247 -80.022 1.00 30.52  ? 107 LYS L2 CB  1 
ATOM 5175 C CG  . LYS B 2 107 ? 115.795 105.191 -81.476 1.00 33.07  ? 107 LYS L2 CG  1 
ATOM 5176 C CD  . LYS B 2 107 ? 115.441 103.855 -82.101 1.00 36.30  ? 107 LYS L2 CD  1 
ATOM 5177 C CE  . LYS B 2 107 ? 116.463 103.449 -83.142 1.00 39.11  ? 107 LYS L2 CE  1 
ATOM 5178 N NZ  . LYS B 2 107 ? 117.736 103.005 -82.518 1.00 42.88  ? 107 LYS L2 NZ  1 
ATOM 5179 N N   . ARG B 2 108 ? 118.844 105.190 -79.234 1.00 23.19  ? 108 ARG L2 N   1 
ATOM 5180 C CA  . ARG B 2 108 ? 120.050 105.998 -79.394 1.00 20.62  ? 108 ARG L2 CA  1 
ATOM 5181 C C   . ARG B 2 108 ? 120.329 106.267 -80.867 1.00 20.39  ? 108 ARG L2 C   1 
ATOM 5182 O O   . ARG B 2 108 ? 120.219 107.403 -81.327 1.00 20.89  ? 108 ARG L2 O   1 
ATOM 5183 C CB  . ARG B 2 108 ? 121.263 105.324 -78.745 1.00 20.42  ? 108 ARG L2 CB  1 
ATOM 5184 C CG  . ARG B 2 108 ? 121.511 103.891 -79.176 1.00 20.59  ? 108 ARG L2 CG  1 
ATOM 5185 C CD  . ARG B 2 108 ? 122.872 103.416 -78.688 1.00 21.49  ? 108 ARG L2 CD  1 
ATOM 5186 N NE  . ARG B 2 108 ? 122.962 101.959 -78.626 1.00 19.54  ? 108 ARG L2 NE  1 
ATOM 5187 C CZ  . ARG B 2 108 ? 123.353 101.181 -79.629 1.00 19.15  ? 108 ARG L2 CZ  1 
ATOM 5188 N NH1 . ARG B 2 108 ? 123.695 101.712 -80.793 1.00 18.91  ? 108 ARG L2 NH1 1 
ATOM 5189 N NH2 . ARG B 2 108 ? 123.400 99.868  -79.462 1.00 21.35  ? 108 ARG L2 NH2 1 
ATOM 5190 N N   . ALA C 3 1   ? 97.647  99.523  -46.478 1.00 47.86  ? 1   ALA H2 N   1 
ATOM 5191 C CA  . ALA C 3 1   ? 98.446  99.367  -45.270 1.00 46.01  ? 1   ALA H2 CA  1 
ATOM 5192 C C   . ALA C 3 1   ? 99.133  98.015  -45.260 1.00 44.99  ? 1   ALA H2 C   1 
ATOM 5193 O O   . ALA C 3 1   ? 99.945  97.728  -44.381 1.00 44.58  ? 1   ALA H2 O   1 
ATOM 5194 C CB  . ALA C 3 1   ? 97.581  99.528  -44.036 1.00 46.40  ? 1   ALA H2 CB  1 
ATOM 5195 N N   . VAL C 3 2   ? 98.794  97.188  -46.241 1.00 44.13  ? 2   VAL H2 N   1 
ATOM 5196 C CA  . VAL C 3 2   ? 99.341  95.843  -46.348 1.00 42.52  ? 2   VAL H2 CA  1 
ATOM 5197 C C   . VAL C 3 2   ? 100.809 95.911  -46.751 1.00 42.71  ? 2   VAL H2 C   1 
ATOM 5198 O O   . VAL C 3 2   ? 101.199 96.645  -47.667 1.00 41.71  ? 2   VAL H2 O   1 
ATOM 5199 C CB  . VAL C 3 2   ? 98.476  95.002  -47.306 1.00 41.54  ? 2   VAL H2 CB  1 
ATOM 5200 C CG1 . VAL C 3 2   ? 98.265  95.722  -48.591 1.00 40.51  ? 2   VAL H2 CG1 1 
ATOM 5201 C CG2 . VAL C 3 2   ? 99.114  93.666  -47.587 1.00 41.68  ? 2   VAL H2 CG2 1 
ATOM 5202 N N   . HIS C 3 3   ? 101.639 95.178  -46.018 1.00 42.03  ? 3   HIS H2 N   1 
ATOM 5203 C CA  . HIS C 3 3   ? 103.080 95.324  -46.090 1.00 40.82  ? 3   HIS H2 CA  1 
ATOM 5204 C C   . HIS C 3 3   ? 103.732 94.002  -45.738 1.00 39.68  ? 3   HIS H2 C   1 
ATOM 5205 O O   . HIS C 3 3   ? 103.347 93.366  -44.757 1.00 38.35  ? 3   HIS H2 O   1 
ATOM 5206 C CB  . HIS C 3 3   ? 103.556 96.414  -45.129 1.00 42.90  ? 3   HIS H2 CB  1 
ATOM 5207 C CG  . HIS C 3 3   ? 105.016 96.712  -45.232 1.00 45.44  ? 3   HIS H2 CG  1 
ATOM 5208 N ND1 . HIS C 3 3   ? 105.571 97.334  -46.329 1.00 45.59  ? 3   HIS H2 ND1 1 
ATOM 5209 C CD2 . HIS C 3 3   ? 106.035 96.477  -44.375 1.00 45.60  ? 3   HIS H2 CD2 1 
ATOM 5210 C CE1 . HIS C 3 3   ? 106.871 97.465  -46.144 1.00 46.16  ? 3   HIS H2 CE1 1 
ATOM 5211 N NE2 . HIS C 3 3   ? 107.179 96.953  -44.967 1.00 47.08  ? 3   HIS H2 NE2 1 
ATOM 5212 N N   . LEU C 3 4   ? 104.713 93.593  -46.531 1.00 37.26  ? 4   LEU H2 N   1 
ATOM 5213 C CA  . LEU C 3 4   ? 105.473 92.379  -46.281 1.00 37.20  ? 4   LEU H2 CA  1 
ATOM 5214 C C   . LEU C 3 4   ? 106.929 92.749  -46.049 1.00 38.21  ? 4   LEU H2 C   1 
ATOM 5215 O O   . LEU C 3 4   ? 107.444 93.684  -46.666 1.00 37.05  ? 4   LEU H2 O   1 
ATOM 5216 C CB  . LEU C 3 4   ? 105.338 91.394  -47.443 1.00 35.75  ? 4   LEU H2 CB  1 
ATOM 5217 C CG  . LEU C 3 4   ? 103.888 91.144  -47.867 1.00 36.82  ? 4   LEU H2 CG  1 
ATOM 5218 C CD1 . LEU C 3 4   ? 103.784 90.194  -49.024 1.00 37.52  ? 4   LEU H2 CD1 1 
ATOM 5219 C CD2 . LEU C 3 4   ? 103.113 90.595  -46.702 1.00 36.55  ? 4   LEU H2 CD2 1 
ATOM 5220 N N   . GLN C 3 5   ? 107.585 92.028  -45.145 1.00 39.36  ? 5   GLN H2 N   1 
ATOM 5221 C CA  . GLN C 3 5   ? 108.894 92.410  -44.634 1.00 40.56  ? 5   GLN H2 CA  1 
ATOM 5222 C C   . GLN C 3 5   ? 109.821 91.207  -44.643 1.00 40.80  ? 5   GLN H2 C   1 
ATOM 5223 O O   . GLN C 3 5   ? 109.817 90.415  -43.698 1.00 40.18  ? 5   GLN H2 O   1 
ATOM 5224 C CB  . GLN C 3 5   ? 108.764 92.969  -43.218 1.00 41.77  ? 5   GLN H2 CB  1 
ATOM 5225 C CG  . GLN C 3 5   ? 110.032 93.557  -42.652 1.00 42.86  ? 5   GLN H2 CG  1 
ATOM 5226 C CD  . GLN C 3 5   ? 110.301 94.934  -43.196 1.00 44.66  ? 5   GLN H2 CD  1 
ATOM 5227 O OE1 . GLN C 3 5   ? 109.374 95.664  -43.548 1.00 46.45  ? 5   GLN H2 OE1 1 
ATOM 5228 N NE2 . GLN C 3 5   ? 111.570 95.303  -43.269 1.00 42.91  ? 5   GLN H2 NE2 1 
ATOM 5229 N N   . GLY C 3 6   ? 110.620 91.079  -45.691 1.00 40.35  ? 6   GLY H2 N   1 
ATOM 5230 C CA  . GLY C 3 6   ? 111.579 90.001  -45.761 1.00 40.53  ? 6   GLY H2 CA  1 
ATOM 5231 C C   . GLY C 3 6   ? 112.748 90.206  -44.817 1.00 41.51  ? 6   GLY H2 C   1 
ATOM 5232 O O   . GLY C 3 6   ? 112.941 91.280  -44.258 1.00 40.37  ? 6   GLY H2 O   1 
ATOM 5233 N N   . THR C 3 7   ? 113.530 89.152  -44.636 1.00 42.15  ? 7   THR H2 N   1 
ATOM 5234 C CA  . THR C 3 7   ? 114.694 89.190  -43.769 1.00 42.68  ? 7   THR H2 CA  1 
ATOM 5235 C C   . THR C 3 7   ? 115.889 89.770  -44.522 1.00 43.33  ? 7   THR H2 C   1 
ATOM 5236 O O   . THR C 3 7   ? 115.806 90.100  -45.708 1.00 41.97  ? 7   THR H2 O   1 
ATOM 5237 C CB  . THR C 3 7   ? 114.986 87.793  -43.222 1.00 43.14  ? 7   THR H2 CB  1 
ATOM 5238 O OG1 . THR C 3 7   ? 116.112 87.849  -42.340 1.00 42.02  ? 7   THR H2 OG1 1 
ATOM 5239 C CG2 . THR C 3 7   ? 115.269 86.820  -44.344 1.00 44.39  ? 7   THR H2 CG2 1 
ATOM 5240 N N   . GLU C 3 8   ? 117.020 89.889  -43.831 1.00 44.84  ? 8   GLU H2 N   1 
ATOM 5241 C CA  . GLU C 3 8   ? 118.192 90.543  -44.397 1.00 47.95  ? 8   GLU H2 CA  1 
ATOM 5242 C C   . GLU C 3 8   ? 118.991 89.586  -45.278 1.00 47.92  ? 8   GLU H2 C   1 
ATOM 5243 O O   . GLU C 3 8   ? 118.720 88.386  -45.348 1.00 47.64  ? 8   GLU H2 O   1 
ATOM 5244 C CB  . GLU C 3 8   ? 119.067 91.118  -43.282 1.00 52.18  ? 8   GLU H2 CB  1 
ATOM 5245 C CG  . GLU C 3 8   ? 119.339 90.171  -42.114 1.00 56.59  ? 8   GLU H2 CG  1 
ATOM 5246 C CD  . GLU C 3 8   ? 120.611 89.357  -42.270 1.00 58.86  ? 8   GLU H2 CD  1 
ATOM 5247 O OE1 . GLU C 3 8   ? 120.814 88.418  -41.474 1.00 58.45  ? 8   GLU H2 OE1 1 
ATOM 5248 O OE2 . GLU C 3 8   ? 121.415 89.666  -43.168 1.00 60.55  ? 8   GLU H2 OE2 1 
ATOM 5249 N N   . LEU C 3 9   ? 119.994 90.142  -45.953 1.00 47.76  ? 9   LEU H2 N   1 
ATOM 5250 C CA  . LEU C 3 9   ? 120.703 89.423  -47.004 1.00 48.83  ? 9   LEU H2 CA  1 
ATOM 5251 C C   . LEU C 3 9   ? 121.649 88.401  -46.391 1.00 48.49  ? 9   LEU H2 C   1 
ATOM 5252 O O   . LEU C 3 9   ? 122.548 88.760  -45.628 1.00 49.07  ? 9   LEU H2 O   1 
ATOM 5253 C CB  . LEU C 3 9   ? 121.493 90.410  -47.855 1.00 49.85  ? 9   LEU H2 CB  1 
ATOM 5254 C CG  . LEU C 3 9   ? 120.750 91.672  -48.306 1.00 50.29  ? 9   LEU H2 CG  1 
ATOM 5255 C CD1 . LEU C 3 9   ? 121.689 92.581  -49.080 1.00 51.74  ? 9   LEU H2 CD1 1 
ATOM 5256 C CD2 . LEU C 3 9   ? 119.476 91.395  -49.090 1.00 50.61  ? 9   LEU H2 CD2 1 
ATOM 5257 N N   . VAL C 3 10  ? 121.479 87.133  -46.743 1.00 49.34  ? 10  VAL H2 N   1 
ATOM 5258 C CA  . VAL C 3 10  ? 122.184 86.062  -46.051 1.00 50.71  ? 10  VAL H2 CA  1 
ATOM 5259 C C   . VAL C 3 10  ? 123.373 85.585  -46.877 1.00 50.89  ? 10  VAL H2 C   1 
ATOM 5260 O O   . VAL C 3 10  ? 123.419 85.726  -48.104 1.00 50.21  ? 10  VAL H2 O   1 
ATOM 5261 C CB  . VAL C 3 10  ? 121.247 84.888  -45.703 1.00 51.74  ? 10  VAL H2 CB  1 
ATOM 5262 C CG1 . VAL C 3 10  ? 120.069 85.391  -44.896 1.00 50.79  ? 10  VAL H2 CG1 1 
ATOM 5263 C CG2 . VAL C 3 10  ? 120.766 84.187  -46.955 1.00 52.22  ? 10  VAL H2 CG2 1 
ATOM 5264 N N   . LYS C 3 11  ? 124.355 85.035  -46.169 1.00 51.52  ? 11  LYS H2 N   1 
ATOM 5265 C CA  . LYS C 3 11  ? 125.587 84.509  -46.754 1.00 51.83  ? 11  LYS H2 CA  1 
ATOM 5266 C C   . LYS C 3 11  ? 125.787 83.096  -46.219 1.00 52.61  ? 11  LYS H2 C   1 
ATOM 5267 O O   . LYS C 3 11  ? 126.326 82.897  -45.124 1.00 53.45  ? 11  LYS H2 O   1 
ATOM 5268 C CB  . LYS C 3 11  ? 126.771 85.423  -46.423 1.00 51.64  ? 11  LYS H2 CB  1 
ATOM 5269 C CG  . LYS C 3 11  ? 128.156 84.930  -46.855 1.00 52.09  ? 11  LYS H2 CG  1 
ATOM 5270 C CD  . LYS C 3 11  ? 128.207 84.436  -48.285 1.00 52.57  ? 11  LYS H2 CD  1 
ATOM 5271 C CE  . LYS C 3 11  ? 129.419 83.558  -48.502 1.00 53.97  ? 11  LYS H2 CE  1 
ATOM 5272 N NZ  . LYS C 3 11  ? 129.345 82.344  -47.650 1.00 56.33  ? 11  LYS H2 NZ  1 
ATOM 5273 N N   . PRO C 3 12  ? 125.302 82.092  -46.940 1.00 53.43  ? 12  PRO H2 N   1 
ATOM 5274 C CA  . PRO C 3 12  ? 125.539 80.703  -46.544 1.00 53.00  ? 12  PRO H2 CA  1 
ATOM 5275 C C   . PRO C 3 12  ? 126.704 80.078  -47.302 1.00 53.07  ? 12  PRO H2 C   1 
ATOM 5276 O O   . PRO C 3 12  ? 127.145 80.561  -48.343 1.00 53.03  ? 12  PRO H2 O   1 
ATOM 5277 C CB  . PRO C 3 12  ? 124.220 80.023  -46.907 1.00 53.53  ? 12  PRO H2 CB  1 
ATOM 5278 C CG  . PRO C 3 12  ? 123.771 80.763  -48.109 1.00 52.24  ? 12  PRO H2 CG  1 
ATOM 5279 C CD  . PRO C 3 12  ? 124.276 82.183  -47.988 1.00 53.81  ? 12  PRO H2 CD  1 
ATOM 5280 N N   . GLY C 3 13  ? 127.198 78.975  -46.748 1.00 53.22  ? 13  GLY H2 N   1 
ATOM 5281 C CA  . GLY C 3 13  ? 128.106 78.114  -47.474 1.00 52.61  ? 13  GLY H2 CA  1 
ATOM 5282 C C   . GLY C 3 13  ? 127.355 77.175  -48.400 1.00 52.88  ? 13  GLY H2 C   1 
ATOM 5283 O O   . GLY C 3 13  ? 126.131 77.045  -48.358 1.00 52.22  ? 13  GLY H2 O   1 
ATOM 5284 N N   . ALA C 3 14  ? 128.104 76.507  -49.269 1.00 53.39  ? 14  ALA H2 N   1 
ATOM 5285 C CA  . ALA C 3 14  ? 127.487 75.641  -50.274 1.00 54.52  ? 14  ALA H2 CA  1 
ATOM 5286 C C   . ALA C 3 14  ? 127.389 74.194  -49.806 1.00 55.24  ? 14  ALA H2 C   1 
ATOM 5287 O O   . ALA C 3 14  ? 127.772 73.267  -50.516 1.00 56.06  ? 14  ALA H2 O   1 
ATOM 5288 C CB  . ALA C 3 14  ? 128.258 75.743  -51.584 1.00 53.62  ? 14  ALA H2 CB  1 
ATOM 5289 N N   . SER C 3 15  ? 126.865 73.988  -48.598 1.00 55.66  ? 15  SER H2 N   1 
ATOM 5290 C CA  . SER C 3 15  ? 126.672 72.639  -48.082 1.00 55.24  ? 15  SER H2 CA  1 
ATOM 5291 C C   . SER C 3 15  ? 125.269 72.426  -47.527 1.00 54.80  ? 15  SER H2 C   1 
ATOM 5292 O O   . SER C 3 15  ? 124.690 71.348  -47.686 1.00 55.02  ? 15  SER H2 O   1 
ATOM 5293 C CB  . SER C 3 15  ? 127.707 72.332  -46.994 1.00 56.47  ? 15  SER H2 CB  1 
ATOM 5294 O OG  . SER C 3 15  ? 129.002 72.762  -47.373 1.00 57.23  ? 15  SER H2 OG  1 
ATOM 5295 N N   . ALA C 3 16  ? 124.720 73.445  -46.875 1.00 54.35  ? 16  ALA H2 N   1 
ATOM 5296 C CA  . ALA C 3 16  ? 123.511 73.316  -46.077 1.00 53.60  ? 16  ALA H2 CA  1 
ATOM 5297 C C   . ALA C 3 16  ? 122.503 74.380  -46.482 1.00 53.49  ? 16  ALA H2 C   1 
ATOM 5298 O O   . ALA C 3 16  ? 122.643 75.040  -47.511 1.00 54.35  ? 16  ALA H2 O   1 
ATOM 5299 C CB  . ALA C 3 16  ? 123.825 73.416  -44.580 1.00 53.30  ? 16  ALA H2 CB  1 
ATOM 5300 N N   . GLY C 3 17  ? 121.470 74.538  -45.661 1.00 53.08  ? 17  GLY H2 N   1 
ATOM 5301 C CA  . GLY C 3 17  ? 120.389 75.463  -45.947 1.00 52.82  ? 17  GLY H2 CA  1 
ATOM 5302 C C   . GLY C 3 17  ? 120.321 76.606  -44.951 1.00 51.79  ? 17  GLY H2 C   1 
ATOM 5303 O O   . GLY C 3 17  ? 120.850 76.513  -43.844 1.00 52.35  ? 17  GLY H2 O   1 
ATOM 5304 N N   . VAL C 3 18  ? 119.672 77.692  -45.369 1.00 49.97  ? 18  VAL H2 N   1 
ATOM 5305 C CA  . VAL C 3 18  ? 119.453 78.863  -44.531 1.00 48.47  ? 18  VAL H2 CA  1 
ATOM 5306 C C   . VAL C 3 18  ? 118.014 79.317  -44.710 1.00 47.13  ? 18  VAL H2 C   1 
ATOM 5307 O O   . VAL C 3 18  ? 117.559 79.551  -45.835 1.00 48.52  ? 18  VAL H2 O   1 
ATOM 5308 C CB  . VAL C 3 18  ? 120.450 80.001  -44.855 1.00 47.62  ? 18  VAL H2 CB  1 
ATOM 5309 C CG1 . VAL C 3 18  ? 119.901 81.372  -44.452 1.00 47.14  ? 18  VAL H2 CG1 1 
ATOM 5310 C CG2 . VAL C 3 18  ? 121.761 79.757  -44.133 1.00 47.19  ? 18  VAL H2 CG2 1 
ATOM 5311 N N   . LYS C 3 19  ? 117.301 79.431  -43.593 1.00 45.71  ? 19  LYS H2 N   1 
ATOM 5312 C CA  . LYS C 3 19  ? 115.876 79.713  -43.583 1.00 44.59  ? 19  LYS H2 CA  1 
ATOM 5313 C C   . LYS C 3 19  ? 115.610 81.198  -43.769 1.00 43.27  ? 19  LYS H2 C   1 
ATOM 5314 O O   . LYS C 3 19  ? 116.222 82.039  -43.107 1.00 41.83  ? 19  LYS H2 O   1 
ATOM 5315 C CB  . LYS C 3 19  ? 115.263 79.217  -42.272 1.00 46.26  ? 19  LYS H2 CB  1 
ATOM 5316 C CG  . LYS C 3 19  ? 114.044 79.971  -41.785 1.00 48.40  ? 19  LYS H2 CG  1 
ATOM 5317 C CD  . LYS C 3 19  ? 113.559 79.400  -40.476 1.00 49.70  ? 19  LYS H2 CD  1 
ATOM 5318 C CE  . LYS C 3 19  ? 112.948 78.032  -40.673 1.00 50.89  ? 19  LYS H2 CE  1 
ATOM 5319 N NZ  . LYS C 3 19  ? 112.262 77.572  -39.439 1.00 50.86  ? 19  LYS H2 NZ  1 
ATOM 5320 N N   . LEU C 3 20  ? 114.701 81.513  -44.681 1.00 41.42  ? 20  LEU H2 N   1 
ATOM 5321 C CA  . LEU C 3 20  ? 114.277 82.877  -44.944 1.00 40.10  ? 20  LEU H2 CA  1 
ATOM 5322 C C   . LEU C 3 20  ? 112.983 83.159  -44.199 1.00 39.34  ? 20  LEU H2 C   1 
ATOM 5323 O O   . LEU C 3 20  ? 112.343 82.251  -43.672 1.00 39.61  ? 20  LEU H2 O   1 
ATOM 5324 C CB  . LEU C 3 20  ? 114.086 83.103  -46.441 1.00 40.41  ? 20  LEU H2 CB  1 
ATOM 5325 C CG  . LEU C 3 20  ? 115.308 82.769  -47.287 1.00 37.67  ? 20  LEU H2 CG  1 
ATOM 5326 C CD1 . LEU C 3 20  ? 114.913 82.659  -48.726 1.00 40.15  ? 20  LEU H2 CD1 1 
ATOM 5327 C CD2 . LEU C 3 20  ? 116.359 83.832  -47.114 1.00 39.39  ? 20  LEU H2 CD2 1 
ATOM 5328 N N   . SER C 3 21  ? 112.594 84.427  -44.159 1.00 38.35  ? 21  SER H2 N   1 
ATOM 5329 C CA  . SER C 3 21  ? 111.405 84.826  -43.427 1.00 38.40  ? 21  SER H2 CA  1 
ATOM 5330 C C   . SER C 3 21  ? 110.753 86.014  -44.110 1.00 38.68  ? 21  SER H2 C   1 
ATOM 5331 O O   . SER C 3 21  ? 111.384 86.710  -44.906 1.00 37.77  ? 21  SER H2 O   1 
ATOM 5332 C CB  . SER C 3 21  ? 111.729 85.178  -41.979 1.00 38.93  ? 21  SER H2 CB  1 
ATOM 5333 O OG  . SER C 3 21  ? 110.576 85.642  -41.306 1.00 41.12  ? 21  SER H2 OG  1 
ATOM 5334 N N   . CYS C 3 22  ? 109.480 86.240  -43.787 1.00 39.16  ? 22  CYS H2 N   1 
ATOM 5335 C CA  . CYS C 3 22  ? 108.715 87.345  -44.362 1.00 39.91  ? 22  CYS H2 CA  1 
ATOM 5336 C C   . CYS C 3 22  ? 107.557 87.676  -43.427 1.00 40.24  ? 22  CYS H2 C   1 
ATOM 5337 O O   . CYS C 3 22  ? 106.511 87.030  -43.486 1.00 40.70  ? 22  CYS H2 O   1 
ATOM 5338 C CB  . CYS C 3 22  ? 108.206 86.985  -45.745 1.00 40.78  ? 22  CYS H2 CB  1 
ATOM 5339 S SG  . CYS C 3 22  ? 107.155 88.219  -46.481 1.00 43.35  ? 22  CYS H2 SG  1 
ATOM 5340 N N   . LYS C 3 23  ? 107.726 88.695  -42.596 1.00 40.60  ? 23  LYS H2 N   1 
ATOM 5341 C CA  . LYS C 3 23  ? 106.703 89.069  -41.629 1.00 42.72  ? 23  LYS H2 CA  1 
ATOM 5342 C C   . LYS C 3 23  ? 105.654 89.924  -42.328 1.00 42.25  ? 23  LYS H2 C   1 
ATOM 5343 O O   . LYS C 3 23  ? 105.982 90.959  -42.912 1.00 42.01  ? 23  LYS H2 O   1 
ATOM 5344 C CB  . LYS C 3 23  ? 107.317 89.821  -40.450 1.00 44.28  ? 23  LYS H2 CB  1 
ATOM 5345 C CG  . LYS C 3 23  ? 106.433 89.900  -39.211 1.00 47.44  ? 23  LYS H2 CG  1 
ATOM 5346 C CD  . LYS C 3 23  ? 105.688 91.220  -39.093 1.00 49.51  ? 23  LYS H2 CD  1 
ATOM 5347 C CE  . LYS C 3 23  ? 106.619 92.371  -38.758 1.00 50.90  ? 23  LYS H2 CE  1 
ATOM 5348 N NZ  . LYS C 3 23  ? 105.885 93.667  -38.637 1.00 51.38  ? 23  LYS H2 NZ  1 
ATOM 5349 N N   . ALA C 3 24  ? 104.401 89.500  -42.252 1.00 41.71  ? 24  ALA H2 N   1 
ATOM 5350 C CA  . ALA C 3 24  ? 103.281 90.201  -42.859 1.00 41.56  ? 24  ALA H2 CA  1 
ATOM 5351 C C   . ALA C 3 24  ? 102.683 91.200  -41.880 1.00 41.97  ? 24  ALA H2 C   1 
ATOM 5352 O O   . ALA C 3 24  ? 102.798 91.054  -40.662 1.00 42.69  ? 24  ALA H2 O   1 
ATOM 5353 C CB  . ALA C 3 24  ? 102.212 89.209  -43.307 1.00 40.88  ? 24  ALA H2 CB  1 
ATOM 5354 N N   . SER C 3 25  ? 102.022 92.215  -42.425 1.00 41.81  ? 25  SER H2 N   1 
ATOM 5355 C CA  . SER C 3 25  ? 101.520 93.305  -41.599 1.00 41.67  ? 25  SER H2 CA  1 
ATOM 5356 C C   . SER C 3 25  ? 100.404 94.035  -42.329 1.00 40.73  ? 25  SER H2 C   1 
ATOM 5357 O O   . SER C 3 25  ? 100.374 94.096  -43.559 1.00 39.14  ? 25  SER H2 O   1 
ATOM 5358 C CB  . SER C 3 25  ? 102.645 94.274  -41.231 1.00 42.27  ? 25  SER H2 CB  1 
ATOM 5359 O OG  . SER C 3 25  ? 103.502 94.492  -42.336 1.00 43.50  ? 25  SER H2 OG  1 
ATOM 5360 N N   . GLY C 3 26  ? 99.479  94.583  -41.549 1.00 40.02  ? 26  GLY H2 N   1 
ATOM 5361 C CA  . GLY C 3 26  ? 98.418  95.410  -42.080 1.00 39.40  ? 26  GLY H2 CA  1 
ATOM 5362 C C   . GLY C 3 26  ? 97.206  94.672  -42.601 1.00 39.38  ? 26  GLY H2 C   1 
ATOM 5363 O O   . GLY C 3 26  ? 96.314  95.314  -43.170 1.00 39.71  ? 26  GLY H2 O   1 
ATOM 5364 N N   . TYR C 3 27  ? 97.144  93.355  -42.436 1.00 39.00  ? 27  TYR H2 N   1 
ATOM 5365 C CA  . TYR C 3 27  ? 96.019  92.568  -42.913 1.00 39.89  ? 27  TYR H2 CA  1 
ATOM 5366 C C   . TYR C 3 27  ? 95.948  91.280  -42.108 1.00 40.45  ? 27  TYR H2 C   1 
ATOM 5367 O O   . TYR C 3 27  ? 96.912  90.879  -41.452 1.00 40.63  ? 27  TYR H2 O   1 
ATOM 5368 C CB  . TYR C 3 27  ? 96.127  92.285  -44.416 1.00 38.71  ? 27  TYR H2 CB  1 
ATOM 5369 C CG  . TYR C 3 27  ? 97.180  91.271  -44.802 1.00 38.09  ? 27  TYR H2 CG  1 
ATOM 5370 C CD1 . TYR C 3 27  ? 98.527  91.583  -44.748 1.00 38.14  ? 27  TYR H2 CD1 1 
ATOM 5371 C CD2 . TYR C 3 27  ? 96.823  90.015  -45.246 1.00 37.41  ? 27  TYR H2 CD2 1 
ATOM 5372 C CE1 . TYR C 3 27  ? 99.481  90.669  -45.113 1.00 36.67  ? 27  TYR H2 CE1 1 
ATOM 5373 C CE2 . TYR C 3 27  ? 97.773  89.089  -45.598 1.00 38.43  ? 27  TYR H2 CE2 1 
ATOM 5374 C CZ  . TYR C 3 27  ? 99.100  89.426  -45.532 1.00 37.11  ? 27  TYR H2 CZ  1 
ATOM 5375 O OH  . TYR C 3 27  ? 100.050 88.506  -45.889 1.00 37.87  ? 27  TYR H2 OH  1 
ATOM 5376 N N   . THR C 3 28  ? 94.787  90.631  -42.163 1.00 42.55  ? 28  THR H2 N   1 
ATOM 5377 C CA  . THR C 3 28  ? 94.572  89.358  -41.485 1.00 43.37  ? 28  THR H2 CA  1 
ATOM 5378 C C   . THR C 3 28  ? 95.359  88.284  -42.214 1.00 43.27  ? 28  THR H2 C   1 
ATOM 5379 O O   . THR C 3 28  ? 95.171  88.078  -43.415 1.00 43.38  ? 28  THR H2 O   1 
ATOM 5380 C CB  . THR C 3 28  ? 93.087  89.022  -41.440 1.00 43.89  ? 28  THR H2 CB  1 
ATOM 5381 O OG1 . THR C 3 28  ? 92.546  89.074  -42.764 1.00 44.61  ? 28  THR H2 OG1 1 
ATOM 5382 C CG2 . THR C 3 28  ? 92.351  89.999  -40.551 1.00 44.16  ? 28  THR H2 CG2 1 
ATOM 5383 N N   . PHE C 3 29  ? 96.229  87.593  -41.478 1.00 43.98  ? 29  PHE H2 N   1 
ATOM 5384 C CA  . PHE C 3 29  ? 97.238  86.740  -42.093 1.00 43.88  ? 29  PHE H2 CA  1 
ATOM 5385 C C   . PHE C 3 29  ? 96.622  85.520  -42.759 1.00 43.25  ? 29  PHE H2 C   1 
ATOM 5386 O O   . PHE C 3 29  ? 97.088  85.081  -43.815 1.00 43.28  ? 29  PHE H2 O   1 
ATOM 5387 C CB  . PHE C 3 29  ? 98.252  86.314  -41.036 1.00 43.69  ? 29  PHE H2 CB  1 
ATOM 5388 C CG  . PHE C 3 29  ? 99.427  85.578  -41.584 1.00 44.42  ? 29  PHE H2 CG  1 
ATOM 5389 C CD1 . PHE C 3 29  ? 100.126 86.074  -42.660 1.00 44.56  ? 29  PHE H2 CD1 1 
ATOM 5390 C CD2 . PHE C 3 29  ? 99.849  84.402  -41.005 1.00 44.34  ? 29  PHE H2 CD2 1 
ATOM 5391 C CE1 . PHE C 3 29  ? 101.212 85.403  -43.154 1.00 45.74  ? 29  PHE H2 CE1 1 
ATOM 5392 C CE2 . PHE C 3 29  ? 100.935 83.725  -41.500 1.00 44.40  ? 29  PHE H2 CE2 1 
ATOM 5393 C CZ  . PHE C 3 29  ? 101.610 84.224  -42.577 1.00 45.40  ? 29  PHE H2 CZ  1 
ATOM 5394 N N   . THR C 3 30  ? 95.555  84.983  -42.185 1.00 43.38  ? 30  THR H2 N   1 
ATOM 5395 C CA  . THR C 3 30  ? 95.067  83.681  -42.604 1.00 43.60  ? 30  THR H2 CA  1 
ATOM 5396 C C   . THR C 3 30  ? 94.201  83.724  -43.851 1.00 43.07  ? 30  THR H2 C   1 
ATOM 5397 O O   . THR C 3 30  ? 93.864  82.660  -44.377 1.00 43.41  ? 30  THR H2 O   1 
ATOM 5398 C CB  . THR C 3 30  ? 94.297  83.031  -41.462 1.00 44.18  ? 30  THR H2 CB  1 
ATOM 5399 O OG1 . THR C 3 30  ? 93.429  83.998  -40.867 1.00 47.37  ? 30  THR H2 OG1 1 
ATOM 5400 C CG2 . THR C 3 30  ? 95.267  82.522  -40.411 1.00 45.49  ? 30  THR H2 CG2 1 
ATOM 5401 N N   . ASN C 3 31  ? 93.858  84.901  -44.356 1.00 41.62  ? 31  ASN H2 N   1 
ATOM 5402 C CA  . ASN C 3 31  ? 92.975  84.986  -45.509 1.00 40.00  ? 31  ASN H2 CA  1 
ATOM 5403 C C   . ASN C 3 31  ? 93.698  84.861  -46.837 1.00 38.91  ? 31  ASN H2 C   1 
ATOM 5404 O O   . ASN C 3 31  ? 93.038  84.671  -47.862 1.00 38.63  ? 31  ASN H2 O   1 
ATOM 5405 C CB  . ASN C 3 31  ? 92.210  86.303  -45.488 1.00 41.09  ? 31  ASN H2 CB  1 
ATOM 5406 C CG  . ASN C 3 31  ? 91.357  86.446  -44.264 1.00 43.39  ? 31  ASN H2 CG  1 
ATOM 5407 O OD1 . ASN C 3 31  ? 91.587  85.782  -43.261 1.00 45.09  ? 31  ASN H2 OD1 1 
ATOM 5408 N ND2 . ASN C 3 31  ? 90.362  87.315  -44.332 1.00 45.04  ? 31  ASN H2 ND2 1 
ATOM 5409 N N   . TYR C 3 32  ? 95.020  84.975  -46.855 1.00 36.92  ? 32  TYR H2 N   1 
ATOM 5410 C CA  . TYR C 3 32  ? 95.781  85.009  -48.094 1.00 36.72  ? 32  TYR H2 CA  1 
ATOM 5411 C C   . TYR C 3 32  ? 96.997  84.119  -47.940 1.00 34.80  ? 32  TYR H2 C   1 
ATOM 5412 O O   . TYR C 3 32  ? 97.700  84.193  -46.930 1.00 34.49  ? 32  TYR H2 O   1 
ATOM 5413 C CB  . TYR C 3 32  ? 96.221  86.430  -48.451 1.00 37.04  ? 32  TYR H2 CB  1 
ATOM 5414 C CG  . TYR C 3 32  ? 95.096  87.411  -48.654 1.00 37.33  ? 32  TYR H2 CG  1 
ATOM 5415 C CD1 . TYR C 3 32  ? 94.530  88.079  -47.578 1.00 39.88  ? 32  TYR H2 CD1 1 
ATOM 5416 C CD2 . TYR C 3 32  ? 94.613  87.686  -49.922 1.00 38.21  ? 32  TYR H2 CD2 1 
ATOM 5417 C CE1 . TYR C 3 32  ? 93.502  88.969  -47.753 1.00 39.52  ? 32  TYR H2 CE1 1 
ATOM 5418 C CE2 . TYR C 3 32  ? 93.585  88.583  -50.111 1.00 40.71  ? 32  TYR H2 CE2 1 
ATOM 5419 C CZ  . TYR C 3 32  ? 93.035  89.219  -49.021 1.00 40.65  ? 32  TYR H2 CZ  1 
ATOM 5420 O OH  . TYR C 3 32  ? 92.014  90.120  -49.195 1.00 42.55  ? 32  TYR H2 OH  1 
ATOM 5421 N N   . ASP C 3 33  ? 97.240  83.284  -48.938 1.00 33.34  ? 33  ASP H2 N   1 
ATOM 5422 C CA  . ASP C 3 33  ? 98.435  82.465  -48.950 1.00 33.57  ? 33  ASP H2 CA  1 
ATOM 5423 C C   . ASP C 3 33  ? 99.643  83.296  -49.348 1.00 33.23  ? 33  ASP H2 C   1 
ATOM 5424 O O   . ASP C 3 33  ? 99.534  84.279  -50.082 1.00 31.90  ? 33  ASP H2 O   1 
ATOM 5425 C CB  . ASP C 3 33  ? 98.275  81.316  -49.923 1.00 34.12  ? 33  ASP H2 CB  1 
ATOM 5426 C CG  . ASP C 3 33  ? 97.848  81.781  -51.281 1.00 35.01  ? 33  ASP H2 CG  1 
ATOM 5427 O OD1 . ASP C 3 33  ? 97.255  82.871  -51.367 1.00 35.42  ? 33  ASP H2 OD1 1 
ATOM 5428 O OD2 . ASP C 3 33  ? 98.102  81.062  -52.265 1.00 36.84  ? 33  ASP H2 OD2 1 
ATOM 5429 N N   . MET C 3 34  ? 100.805 82.881  -48.868 1.00 31.01  ? 34  MET H2 N   1 
ATOM 5430 C CA  . MET C 3 34  ? 102.057 83.568  -49.134 1.00 32.71  ? 34  MET H2 CA  1 
ATOM 5431 C C   . MET C 3 34  ? 102.820 82.790  -50.189 1.00 31.97  ? 34  MET H2 C   1 
ATOM 5432 O O   . MET C 3 34  ? 103.287 81.682  -49.928 1.00 33.00  ? 34  MET H2 O   1 
ATOM 5433 C CB  . MET C 3 34  ? 102.883 83.703  -47.865 1.00 33.42  ? 34  MET H2 CB  1 
ATOM 5434 C CG  . MET C 3 34  ? 103.881 84.821  -47.943 1.00 34.22  ? 34  MET H2 CG  1 
ATOM 5435 S SD  . MET C 3 34  ? 103.038 86.404  -47.924 1.00 37.94  ? 34  MET H2 SD  1 
ATOM 5436 C CE  . MET C 3 34  ? 102.791 86.610  -46.172 1.00 36.96  ? 34  MET H2 CE  1 
ATOM 5437 N N   . ASN C 3 35  ? 102.947 83.368  -51.373 1.00 30.16  ? 35  ASN H2 N   1 
ATOM 5438 C CA  . ASN C 3 35  ? 103.712 82.751  -52.439 1.00 29.81  ? 35  ASN H2 CA  1 
ATOM 5439 C C   . ASN C 3 35  ? 105.157 83.203  -52.359 1.00 30.81  ? 35  ASN H2 C   1 
ATOM 5440 O O   . ASN C 3 35  ? 105.450 84.339  -51.987 1.00 31.68  ? 35  ASN H2 O   1 
ATOM 5441 C CB  . ASN C 3 35  ? 103.133 83.111  -53.802 1.00 29.30  ? 35  ASN H2 CB  1 
ATOM 5442 C CG  . ASN C 3 35  ? 101.663 82.804  -53.909 1.00 28.62  ? 35  ASN H2 CG  1 
ATOM 5443 O OD1 . ASN C 3 35  ? 101.280 81.759  -54.410 1.00 29.67  ? 35  ASN H2 OD1 1 
ATOM 5444 N ND2 . ASN C 3 35  ? 100.829 83.729  -53.469 1.00 26.86  ? 35  ASN H2 ND2 1 
ATOM 5445 N N   . TRP C 3 36  ? 106.065 82.303  -52.711 1.00 30.79  ? 36  TRP H2 N   1 
ATOM 5446 C CA  . TRP C 3 36  ? 107.485 82.609  -52.749 1.00 31.46  ? 36  TRP H2 CA  1 
ATOM 5447 C C   . TRP C 3 36  ? 107.975 82.545  -54.184 1.00 30.81  ? 36  TRP H2 C   1 
ATOM 5448 O O   . TRP C 3 36  ? 107.742 81.561  -54.886 1.00 29.44  ? 36  TRP H2 O   1 
ATOM 5449 C CB  . TRP C 3 36  ? 108.281 81.655  -51.875 1.00 33.44  ? 36  TRP H2 CB  1 
ATOM 5450 C CG  . TRP C 3 36  ? 108.084 81.908  -50.433 1.00 35.98  ? 36  TRP H2 CG  1 
ATOM 5451 C CD1 . TRP C 3 36  ? 107.133 81.367  -49.640 1.00 36.75  ? 36  TRP H2 CD1 1 
ATOM 5452 C CD2 . TRP C 3 36  ? 108.848 82.784  -49.603 1.00 36.81  ? 36  TRP H2 CD2 1 
ATOM 5453 N NE1 . TRP C 3 36  ? 107.251 81.841  -48.363 1.00 37.02  ? 36  TRP H2 NE1 1 
ATOM 5454 C CE2 . TRP C 3 36  ? 108.299 82.718  -48.315 1.00 38.02  ? 36  TRP H2 CE2 1 
ATOM 5455 C CE3 . TRP C 3 36  ? 109.945 83.620  -49.825 1.00 36.79  ? 36  TRP H2 CE3 1 
ATOM 5456 C CZ2 . TRP C 3 36  ? 108.809 83.444  -47.253 1.00 38.36  ? 36  TRP H2 CZ2 1 
ATOM 5457 C CZ3 . TRP C 3 36  ? 110.446 84.342  -48.768 1.00 37.69  ? 36  TRP H2 CZ3 1 
ATOM 5458 C CH2 . TRP C 3 36  ? 109.879 84.249  -47.501 1.00 39.12  ? 36  TRP H2 CH2 1 
ATOM 5459 N N   . VAL C 3 37  ? 108.650 83.606  -54.617 1.00 29.82  ? 37  VAL H2 N   1 
ATOM 5460 C CA  . VAL C 3 37  ? 109.116 83.737  -55.991 1.00 27.96  ? 37  VAL H2 CA  1 
ATOM 5461 C C   . VAL C 3 37  ? 110.623 83.961  -55.962 1.00 29.01  ? 37  VAL H2 C   1 
ATOM 5462 O O   . VAL C 3 37  ? 111.105 84.833  -55.236 1.00 27.29  ? 37  VAL H2 O   1 
ATOM 5463 C CB  . VAL C 3 37  ? 108.424 84.891  -56.735 1.00 27.11  ? 37  VAL H2 CB  1 
ATOM 5464 C CG1 . VAL C 3 37  ? 108.899 84.950  -58.153 1.00 23.79  ? 37  VAL H2 CG1 1 
ATOM 5465 C CG2 . VAL C 3 37  ? 106.927 84.729  -56.713 1.00 26.90  ? 37  VAL H2 CG2 1 
ATOM 5466 N N   . ARG C 3 38  ? 111.364 83.178  -56.742 1.00 29.75  ? 38  ARG H2 N   1 
ATOM 5467 C CA  . ARG C 3 38  ? 112.804 83.354  -56.878 1.00 31.22  ? 38  ARG H2 CA  1 
ATOM 5468 C C   . ARG C 3 38  ? 113.136 84.089  -58.166 1.00 31.23  ? 38  ARG H2 C   1 
ATOM 5469 O O   . ARG C 3 38  ? 112.630 83.743  -59.233 1.00 31.56  ? 38  ARG H2 O   1 
ATOM 5470 C CB  . ARG C 3 38  ? 113.506 81.999  -56.881 1.00 31.52  ? 38  ARG H2 CB  1 
ATOM 5471 C CG  . ARG C 3 38  ? 115.003 82.093  -56.860 1.00 34.73  ? 38  ARG H2 CG  1 
ATOM 5472 C CD  . ARG C 3 38  ? 115.632 80.749  -57.063 1.00 37.73  ? 38  ARG H2 CD  1 
ATOM 5473 N NE  . ARG C 3 38  ? 115.375 80.224  -58.394 1.00 39.26  ? 38  ARG H2 NE  1 
ATOM 5474 C CZ  . ARG C 3 38  ? 115.822 79.051  -58.824 1.00 39.57  ? 38  ARG H2 CZ  1 
ATOM 5475 N NH1 . ARG C 3 38  ? 116.543 78.283  -58.021 1.00 38.81  ? 38  ARG H2 NH1 1 
ATOM 5476 N NH2 . ARG C 3 38  ? 115.549 78.646  -60.056 1.00 40.86  ? 38  ARG H2 NH2 1 
ATOM 5477 N N   . GLN C 3 39  ? 114.011 85.088  -58.073 1.00 31.78  ? 39  GLN H2 N   1 
ATOM 5478 C CA  . GLN C 3 39  ? 114.442 85.847  -59.245 1.00 32.51  ? 39  GLN H2 CA  1 
ATOM 5479 C C   . GLN C 3 39  ? 115.950 85.710  -59.408 1.00 35.57  ? 39  GLN H2 C   1 
ATOM 5480 O O   . GLN C 3 39  ? 116.714 86.436  -58.768 1.00 34.62  ? 39  GLN H2 O   1 
ATOM 5481 C CB  . GLN C 3 39  ? 114.049 87.313  -59.137 1.00 31.20  ? 39  GLN H2 CB  1 
ATOM 5482 C CG  . GLN C 3 39  ? 114.387 88.109  -60.387 1.00 27.16  ? 39  GLN H2 CG  1 
ATOM 5483 C CD  . GLN C 3 39  ? 113.948 89.547  -60.310 1.00 27.50  ? 39  GLN H2 CD  1 
ATOM 5484 O OE1 . GLN C 3 39  ? 113.968 90.155  -59.249 1.00 24.27  ? 39  GLN H2 OE1 1 
ATOM 5485 N NE2 . GLN C 3 39  ? 113.542 90.100  -61.439 1.00 26.12  ? 39  GLN H2 NE2 1 
ATOM 5486 N N   . ARG C 3 40  ? 116.377 84.788  -60.256 1.00 38.09  ? 40  ARG H2 N   1 
ATOM 5487 C CA  . ARG C 3 40  ? 117.769 84.820  -60.658 1.00 41.16  ? 40  ARG H2 CA  1 
ATOM 5488 C C   . ARG C 3 40  ? 117.967 85.946  -61.665 1.00 43.76  ? 40  ARG H2 C   1 
ATOM 5489 O O   . ARG C 3 40  ? 117.049 86.279  -62.418 1.00 44.17  ? 40  ARG H2 O   1 
ATOM 5490 C CB  . ARG C 3 40  ? 118.186 83.497  -61.281 1.00 41.23  ? 40  ARG H2 CB  1 
ATOM 5491 C CG  . ARG C 3 40  ? 118.203 82.347  -60.314 1.00 42.67  ? 40  ARG H2 CG  1 
ATOM 5492 C CD  . ARG C 3 40  ? 119.050 81.197  -60.809 1.00 43.71  ? 40  ARG H2 CD  1 
ATOM 5493 N NE  . ARG C 3 40  ? 120.437 81.592  -61.035 1.00 45.93  ? 40  ARG H2 NE  1 
ATOM 5494 C CZ  . ARG C 3 40  ? 121.368 81.640  -60.089 1.00 46.47  ? 40  ARG H2 CZ  1 
ATOM 5495 N NH1 . ARG C 3 40  ? 121.068 81.319  -58.843 1.00 46.57  ? 40  ARG H2 NH1 1 
ATOM 5496 N NH2 . ARG C 3 40  ? 122.604 82.008  -60.393 1.00 47.27  ? 40  ARG H2 NH2 1 
ATOM 5497 N N   . PRO C 3 41  ? 119.153 86.559  -61.696 1.00 45.78  ? 41  PRO H2 N   1 
ATOM 5498 C CA  . PRO C 3 41  ? 119.401 87.603  -62.707 1.00 48.47  ? 41  PRO H2 CA  1 
ATOM 5499 C C   . PRO C 3 41  ? 119.549 87.077  -64.131 1.00 50.81  ? 41  PRO H2 C   1 
ATOM 5500 O O   . PRO C 3 41  ? 119.659 87.891  -65.055 1.00 51.32  ? 41  PRO H2 O   1 
ATOM 5501 C CB  . PRO C 3 41  ? 120.691 88.273  -62.216 1.00 47.18  ? 41  PRO H2 CB  1 
ATOM 5502 C CG  . PRO C 3 41  ? 121.309 87.295  -61.269 1.00 47.85  ? 41  PRO H2 CG  1 
ATOM 5503 C CD  . PRO C 3 41  ? 120.185 86.545  -60.645 1.00 46.37  ? 41  PRO H2 CD  1 
ATOM 5504 N N   . GLU C 3 42  ? 119.559 85.761  -64.347 1.00 52.92  ? 42  GLU H2 N   1 
ATOM 5505 C CA  . GLU C 3 42  ? 119.599 85.193  -65.691 1.00 54.42  ? 42  GLU H2 CA  1 
ATOM 5506 C C   . GLU C 3 42  ? 118.268 84.565  -66.098 1.00 55.19  ? 42  GLU H2 C   1 
ATOM 5507 O O   . GLU C 3 42  ? 117.862 84.677  -67.257 1.00 55.69  ? 42  GLU H2 O   1 
ATOM 5508 C CB  . GLU C 3 42  ? 120.734 84.162  -65.801 1.00 56.58  ? 42  GLU H2 CB  1 
ATOM 5509 C CG  . GLU C 3 42  ? 120.772 83.116  -64.698 1.00 60.25  ? 42  GLU H2 CG  1 
ATOM 5510 C CD  . GLU C 3 42  ? 121.714 83.483  -63.576 1.00 62.16  ? 42  GLU H2 CD  1 
ATOM 5511 O OE1 . GLU C 3 42  ? 122.629 82.692  -63.276 1.00 62.87  ? 42  GLU H2 OE1 1 
ATOM 5512 O OE2 . GLU C 3 42  ? 121.543 84.568  -63.002 1.00 62.33  ? 42  GLU H2 OE2 1 
ATOM 5513 N N   . GLN C 3 43  ? 117.580 83.905  -65.165 1.00 54.27  ? 43  GLN H2 N   1 
ATOM 5514 C CA  . GLN C 3 43  ? 116.421 83.079  -65.489 1.00 52.52  ? 43  GLN H2 CA  1 
ATOM 5515 C C   . GLN C 3 43  ? 115.088 83.785  -65.288 1.00 50.24  ? 43  GLN H2 C   1 
ATOM 5516 O O   . GLN C 3 43  ? 114.047 83.137  -65.428 1.00 50.02  ? 43  GLN H2 O   1 
ATOM 5517 C CB  . GLN C 3 43  ? 116.442 81.795  -64.656 1.00 53.83  ? 43  GLN H2 CB  1 
ATOM 5518 C CG  . GLN C 3 43  ? 117.741 81.026  -64.742 1.00 55.76  ? 43  GLN H2 CG  1 
ATOM 5519 C CD  . GLN C 3 43  ? 117.529 79.542  -64.926 1.00 57.06  ? 43  GLN H2 CD  1 
ATOM 5520 O OE1 . GLN C 3 43  ? 116.468 79.010  -64.602 1.00 58.66  ? 43  GLN H2 OE1 1 
ATOM 5521 N NE2 . GLN C 3 43  ? 118.535 78.862  -65.465 1.00 57.88  ? 43  GLN H2 NE2 1 
ATOM 5522 N N   . GLY C 3 44  ? 115.083 85.076  -64.977 1.00 47.05  ? 44  GLY H2 N   1 
ATOM 5523 C CA  . GLY C 3 44  ? 113.813 85.722  -64.728 1.00 41.60  ? 44  GLY H2 CA  1 
ATOM 5524 C C   . GLY C 3 44  ? 113.260 85.322  -63.370 1.00 38.31  ? 44  GLY H2 C   1 
ATOM 5525 O O   . GLY C 3 44  ? 113.986 84.906  -62.466 1.00 37.02  ? 44  GLY H2 O   1 
ATOM 5526 N N   . LEU C 3 45  ? 111.944 85.445  -63.237 1.00 35.44  ? 45  LEU H2 N   1 
ATOM 5527 C CA  . LEU C 3 45  ? 111.295 85.082  -61.990 1.00 33.01  ? 45  LEU H2 CA  1 
ATOM 5528 C C   . LEU C 3 45  ? 110.808 83.643  -62.043 1.00 33.61  ? 45  LEU H2 C   1 
ATOM 5529 O O   . LEU C 3 45  ? 110.379 83.147  -63.085 1.00 32.11  ? 45  LEU H2 O   1 
ATOM 5530 C CB  . LEU C 3 45  ? 110.127 86.010  -61.680 1.00 31.22  ? 45  LEU H2 CB  1 
ATOM 5531 C CG  . LEU C 3 45  ? 110.476 87.435  -61.266 1.00 29.52  ? 45  LEU H2 CG  1 
ATOM 5532 C CD1 . LEU C 3 45  ? 110.435 88.339  -62.454 1.00 28.91  ? 45  LEU H2 CD1 1 
ATOM 5533 C CD2 . LEU C 3 45  ? 109.567 87.958  -60.207 1.00 26.95  ? 45  LEU H2 CD2 1 
ATOM 5534 N N   . GLU C 3 46  ? 110.874 82.976  -60.900 1.00 32.98  ? 46  GLU H2 N   1 
ATOM 5535 C CA  . GLU C 3 46  ? 110.517 81.572  -60.788 1.00 35.40  ? 46  GLU H2 CA  1 
ATOM 5536 C C   . GLU C 3 46  ? 109.654 81.398  -59.554 1.00 35.94  ? 46  GLU H2 C   1 
ATOM 5537 O O   . GLU C 3 46  ? 110.054 81.792  -58.458 1.00 35.01  ? 46  GLU H2 O   1 
ATOM 5538 C CB  . GLU C 3 46  ? 111.763 80.696  -60.674 1.00 34.47  ? 46  GLU H2 CB  1 
ATOM 5539 C CG  . GLU C 3 46  ? 111.582 79.251  -61.047 1.00 38.04  ? 46  GLU H2 CG  1 
ATOM 5540 C CD  . GLU C 3 46  ? 111.681 79.030  -62.538 1.00 40.19  ? 46  GLU H2 CD  1 
ATOM 5541 O OE1 . GLU C 3 46  ? 112.303 79.868  -63.222 1.00 40.45  ? 46  GLU H2 OE1 1 
ATOM 5542 O OE2 . GLU C 3 46  ? 111.156 78.011  -63.026 1.00 41.22  ? 46  GLU H2 OE2 1 
ATOM 5543 N N   . TRP C 3 47  ? 108.475 80.815  -59.728 1.00 36.93  ? 47  TRP H2 N   1 
ATOM 5544 C CA  . TRP C 3 47  ? 107.555 80.604  -58.623 1.00 36.76  ? 47  TRP H2 CA  1 
ATOM 5545 C C   . TRP C 3 47  ? 107.894 79.309  -57.902 1.00 37.06  ? 47  TRP H2 C   1 
ATOM 5546 O O   . TRP C 3 47  ? 108.000 78.246  -58.515 1.00 36.69  ? 47  TRP H2 O   1 
ATOM 5547 C CB  . TRP C 3 47  ? 106.116 80.570  -59.132 1.00 36.58  ? 47  TRP H2 CB  1 
ATOM 5548 C CG  . TRP C 3 47  ? 105.092 80.236  -58.106 1.00 38.33  ? 47  TRP H2 CG  1 
ATOM 5549 C CD1 . TRP C 3 47  ? 104.599 81.054  -57.139 1.00 38.36  ? 47  TRP H2 CD1 1 
ATOM 5550 C CD2 . TRP C 3 47  ? 104.414 78.992  -57.962 1.00 39.47  ? 47  TRP H2 CD2 1 
ATOM 5551 N NE1 . TRP C 3 47  ? 103.662 80.393  -56.396 1.00 39.26  ? 47  TRP H2 NE1 1 
ATOM 5552 C CE2 . TRP C 3 47  ? 103.535 79.121  -56.882 1.00 40.02  ? 47  TRP H2 CE2 1 
ATOM 5553 C CE3 . TRP C 3 47  ? 104.471 77.775  -58.642 1.00 39.29  ? 47  TRP H2 CE3 1 
ATOM 5554 C CZ2 . TRP C 3 47  ? 102.720 78.086  -56.470 1.00 41.63  ? 47  TRP H2 CZ2 1 
ATOM 5555 C CZ3 . TRP C 3 47  ? 103.668 76.752  -58.224 1.00 40.29  ? 47  TRP H2 CZ3 1 
ATOM 5556 C CH2 . TRP C 3 47  ? 102.802 76.911  -57.151 1.00 40.80  ? 47  TRP H2 CH2 1 
ATOM 5557 N N   . ILE C 3 48  ? 108.058 79.408  -56.587 1.00 37.47  ? 48  ILE H2 N   1 
ATOM 5558 C CA  . ILE C 3 48  ? 108.498 78.294  -55.752 1.00 39.47  ? 48  ILE H2 CA  1 
ATOM 5559 C C   . ILE C 3 48  ? 107.315 77.536  -55.171 1.00 40.90  ? 48  ILE H2 C   1 
ATOM 5560 O O   . ILE C 3 48  ? 107.229 76.317  -55.297 1.00 41.13  ? 48  ILE H2 O   1 
ATOM 5561 C CB  . ILE C 3 48  ? 109.452 78.780  -54.642 1.00 39.09  ? 48  ILE H2 CB  1 
ATOM 5562 C CG1 . ILE C 3 48  ? 110.589 79.582  -55.259 1.00 39.69  ? 48  ILE H2 CG1 1 
ATOM 5563 C CG2 . ILE C 3 48  ? 109.982 77.613  -53.846 1.00 39.13  ? 48  ILE H2 CG2 1 
ATOM 5564 C CD1 . ILE C 3 48  ? 111.482 80.230  -54.262 1.00 39.75  ? 48  ILE H2 CD1 1 
ATOM 5565 N N   . GLY C 3 49  ? 106.406 78.236  -54.510 1.00 41.81  ? 49  GLY H2 N   1 
ATOM 5566 C CA  . GLY C 3 49  ? 105.204 77.602  -54.012 1.00 42.87  ? 49  GLY H2 CA  1 
ATOM 5567 C C   . GLY C 3 49  ? 104.459 78.532  -53.087 1.00 44.00  ? 49  GLY H2 C   1 
ATOM 5568 O O   . GLY C 3 49  ? 104.968 79.573  -52.682 1.00 43.57  ? 49  GLY H2 O   1 
ATOM 5569 N N   . TRP C 3 50  ? 103.238 78.134  -52.747 1.00 44.69  ? 50  TRP H2 N   1 
ATOM 5570 C CA  . TRP C 3 50  ? 102.460 78.898  -51.789 1.00 46.82  ? 50  TRP H2 CA  1 
ATOM 5571 C C   . TRP C 3 50  ? 102.290 78.134  -50.492 1.00 47.15  ? 50  TRP H2 C   1 
ATOM 5572 O O   . TRP C 3 50  ? 102.633 76.958  -50.387 1.00 47.05  ? 50  TRP H2 O   1 
ATOM 5573 C CB  . TRP C 3 50  ? 101.065 79.308  -52.279 1.00 47.93  ? 50  TRP H2 CB  1 
ATOM 5574 C CG  . TRP C 3 50  ? 100.100 78.256  -52.730 1.00 50.09  ? 50  TRP H2 CG  1 
ATOM 5575 C CD1 . TRP C 3 50  ? 99.495  77.309  -51.970 1.00 50.86  ? 50  TRP H2 CD1 1 
ATOM 5576 C CD2 . TRP C 3 50  ? 99.469  78.193  -54.004 1.00 51.02  ? 50  TRP H2 CD2 1 
ATOM 5577 N NE1 . TRP C 3 50  ? 98.609  76.589  -52.717 1.00 50.83  ? 50  TRP H2 NE1 1 
ATOM 5578 C CE2 . TRP C 3 50  ? 98.569  77.123  -53.975 1.00 51.68  ? 50  TRP H2 CE2 1 
ATOM 5579 C CE3 . TRP C 3 50  ? 99.609  78.916  -55.185 1.00 51.68  ? 50  TRP H2 CE3 1 
ATOM 5580 C CZ2 . TRP C 3 50  ? 97.804  76.773  -55.070 1.00 51.77  ? 50  TRP H2 CZ2 1 
ATOM 5581 C CZ3 . TRP C 3 50  ? 98.864  78.549  -56.272 1.00 52.20  ? 50  TRP H2 CZ3 1 
ATOM 5582 C CH2 . TRP C 3 50  ? 97.979  77.484  -56.213 1.00 52.58  ? 50  TRP H2 CH2 1 
ATOM 5583 N N   . ILE C 3 51  ? 101.754 78.833  -49.503 1.00 47.77  ? 51  ILE H2 N   1 
ATOM 5584 C CA  . ILE C 3 51  ? 101.435 78.270  -48.204 1.00 48.77  ? 51  ILE H2 CA  1 
ATOM 5585 C C   . ILE C 3 51  ? 100.267 79.057  -47.632 1.00 49.30  ? 51  ILE H2 C   1 
ATOM 5586 O O   . ILE C 3 51  ? 100.370 80.267  -47.414 1.00 48.37  ? 51  ILE H2 O   1 
ATOM 5587 C CB  . ILE C 3 51  ? 102.664 78.284  -47.272 1.00 49.06  ? 51  ILE H2 CB  1 
ATOM 5588 C CG1 . ILE C 3 51  ? 102.279 78.062  -45.818 1.00 49.35  ? 51  ILE H2 CG1 1 
ATOM 5589 C CG2 . ILE C 3 51  ? 103.499 79.542  -47.432 1.00 48.88  ? 51  ILE H2 CG2 1 
ATOM 5590 C CD1 . ILE C 3 51  ? 101.842 76.689  -45.513 1.00 49.67  ? 51  ILE H2 CD1 1 
ATOM 5591 N N   . PHE C 3 52  ? 99.153  78.388  -47.424 1.00 50.68  ? 52  PHE H2 N   1 
ATOM 5592 C CA  . PHE C 3 52  ? 98.073  79.000  -46.678 1.00 51.95  ? 52  PHE H2 CA  1 
ATOM 5593 C C   . PHE C 3 52  ? 98.373  78.839  -45.198 1.00 53.08  ? 52  PHE H2 C   1 
ATOM 5594 O O   . PHE C 3 52  ? 98.731  77.739  -44.768 1.00 53.95  ? 52  PHE H2 O   1 
ATOM 5595 C CB  . PHE C 3 52  ? 96.741  78.350  -47.002 1.00 51.18  ? 52  PHE H2 CB  1 
ATOM 5596 C CG  . PHE C 3 52  ? 96.227  78.655  -48.369 1.00 50.31  ? 52  PHE H2 CG  1 
ATOM 5597 C CD1 . PHE C 3 52  ? 96.630  77.900  -49.445 1.00 49.80  ? 52  PHE H2 CD1 1 
ATOM 5598 C CD2 . PHE C 3 52  ? 95.320  79.670  -48.571 1.00 49.20  ? 52  PHE H2 CD2 1 
ATOM 5599 C CE1 . PHE C 3 52  ? 96.153  78.161  -50.697 1.00 50.04  ? 52  PHE H2 CE1 1 
ATOM 5600 C CE2 . PHE C 3 52  ? 94.842  79.937  -49.830 1.00 49.90  ? 52  PHE H2 CE2 1 
ATOM 5601 C CZ  . PHE C 3 52  ? 95.260  79.178  -50.888 1.00 49.86  ? 52  PHE H2 CZ  1 
ATOM 5602 N N   . PRO C 3 53  ? 98.255  79.887  -44.390 1.00 54.32  ? 53  PRO H2 N   1 
ATOM 5603 C CA  . PRO C 3 53  ? 98.314  79.685  -42.936 1.00 55.26  ? 53  PRO H2 CA  1 
ATOM 5604 C C   . PRO C 3 53  ? 97.076  79.003  -42.360 1.00 56.78  ? 53  PRO H2 C   1 
ATOM 5605 O O   . PRO C 3 53  ? 97.058  78.699  -41.162 1.00 55.94  ? 53  PRO H2 O   1 
ATOM 5606 C CB  . PRO C 3 53  ? 98.485  81.105  -42.390 1.00 54.80  ? 53  PRO H2 CB  1 
ATOM 5607 C CG  . PRO C 3 53  ? 98.202  82.003  -43.540 1.00 54.83  ? 53  PRO H2 CG  1 
ATOM 5608 C CD  . PRO C 3 53  ? 98.499  81.281  -44.769 1.00 54.36  ? 53  PRO H2 CD  1 
ATOM 5609 N N   . GLY C 3 54  ? 96.056  78.736  -43.169 1.00 58.21  ? 54  GLY H2 N   1 
ATOM 5610 C CA  . GLY C 3 54  ? 94.927  77.931  -42.761 1.00 60.44  ? 54  GLY H2 CA  1 
ATOM 5611 C C   . GLY C 3 54  ? 95.268  76.457  -42.798 1.00 61.89  ? 54  GLY H2 C   1 
ATOM 5612 O O   . GLY C 3 54  ? 94.981  75.759  -43.776 1.00 61.90  ? 54  GLY H2 O   1 
ATOM 5613 N N   . ASP C 3 55  ? 95.971  76.023  -41.751 1.00 63.27  ? 55  ASP H2 N   1 
ATOM 5614 C CA  . ASP C 3 55  ? 96.328  74.628  -41.472 1.00 64.41  ? 55  ASP H2 CA  1 
ATOM 5615 C C   . ASP C 3 55  ? 97.317  74.083  -42.509 1.00 64.54  ? 55  ASP H2 C   1 
ATOM 5616 O O   . ASP C 3 55  ? 97.401  72.877  -42.736 1.00 64.29  ? 55  ASP H2 O   1 
ATOM 5617 C CB  . ASP C 3 55  ? 95.083  73.736  -41.350 1.00 66.36  ? 55  ASP H2 CB  1 
ATOM 5618 C CG  . ASP C 3 55  ? 95.325  72.491  -40.506 1.00 68.40  ? 55  ASP H2 CG  1 
ATOM 5619 O OD1 . ASP C 3 55  ? 96.452  72.325  -39.998 1.00 68.21  ? 55  ASP H2 OD1 1 
ATOM 5620 O OD2 . ASP C 3 55  ? 94.382  71.684  -40.345 1.00 69.85  ? 55  ASP H2 OD2 1 
ATOM 5621 N N   . GLY C 3 56  ? 98.085  74.975  -43.126 1.00 64.15  ? 56  GLY H2 N   1 
ATOM 5622 C CA  . GLY C 3 56  ? 99.284  74.596  -43.849 1.00 63.95  ? 56  GLY H2 CA  1 
ATOM 5623 C C   . GLY C 3 56  ? 99.125  73.821  -45.139 1.00 63.74  ? 56  GLY H2 C   1 
ATOM 5624 O O   . GLY C 3 56  ? 99.722  72.756  -45.299 1.00 63.64  ? 56  GLY H2 O   1 
ATOM 5625 N N   . SER C 3 57  ? 98.362  74.351  -46.083 1.00 63.21  ? 57  SER H2 N   1 
ATOM 5626 C CA  . SER C 3 57  ? 98.175  73.709  -47.372 1.00 62.51  ? 57  SER H2 CA  1 
ATOM 5627 C C   . SER C 3 57  ? 99.179  74.270  -48.363 1.00 62.60  ? 57  SER H2 C   1 
ATOM 5628 O O   . SER C 3 57  ? 99.018  75.391  -48.849 1.00 62.84  ? 57  SER H2 O   1 
ATOM 5629 C CB  . SER C 3 57  ? 96.763  73.931  -47.894 1.00 63.37  ? 57  SER H2 CB  1 
ATOM 5630 O OG  . SER C 3 57  ? 95.818  73.798  -46.851 1.00 64.95  ? 57  SER H2 OG  1 
ATOM 5631 N N   . THR C 3 58  ? 100.211 73.488  -48.666 1.00 61.58  ? 58  THR H2 N   1 
ATOM 5632 C CA  . THR C 3 58  ? 101.281 73.915  -49.552 1.00 61.76  ? 58  THR H2 CA  1 
ATOM 5633 C C   . THR C 3 58  ? 101.089 73.309  -50.929 1.00 61.66  ? 58  THR H2 C   1 
ATOM 5634 O O   . THR C 3 58  ? 100.529 72.222  -51.075 1.00 63.03  ? 58  THR H2 O   1 
ATOM 5635 C CB  . THR C 3 58  ? 102.654 73.473  -49.059 1.00 61.68  ? 58  THR H2 CB  1 
ATOM 5636 O OG1 . THR C 3 58  ? 102.745 72.050  -49.147 1.00 61.19  ? 58  THR H2 OG1 1 
ATOM 5637 C CG2 . THR C 3 58  ? 102.870 73.874  -47.635 1.00 62.48  ? 58  THR H2 CG2 1 
ATOM 5638 N N   . ARG C 3 59  ? 101.559 74.025  -51.940 1.00 60.39  ? 59  ARG H2 N   1 
ATOM 5639 C CA  . ARG C 3 59  ? 101.908 73.435  -53.220 1.00 59.35  ? 59  ARG H2 CA  1 
ATOM 5640 C C   . ARG C 3 59  ? 103.272 73.963  -53.601 1.00 58.34  ? 59  ARG H2 C   1 
ATOM 5641 O O   . ARG C 3 59  ? 103.754 74.930  -53.017 1.00 58.79  ? 59  ARG H2 O   1 
ATOM 5642 C CB  . ARG C 3 59  ? 100.892 73.733  -54.318 1.00 59.22  ? 59  ARG H2 CB  1 
ATOM 5643 C CG  . ARG C 3 59  ? 99.661  72.863  -54.235 1.00 59.22  ? 59  ARG H2 CG  1 
ATOM 5644 C CD  . ARG C 3 59  ? 98.527  73.391  -55.086 1.00 59.77  ? 59  ARG H2 CD  1 
ATOM 5645 N NE  . ARG C 3 59  ? 98.744  73.345  -56.523 1.00 61.11  ? 59  ARG H2 NE  1 
ATOM 5646 C CZ  . ARG C 3 59  ? 98.278  72.371  -57.288 1.00 61.92  ? 59  ARG H2 CZ  1 
ATOM 5647 N NH1 . ARG C 3 59  ? 97.575  71.392  -56.738 1.00 62.56  ? 59  ARG H2 NH1 1 
ATOM 5648 N NH2 . ARG C 3 59  ? 98.493  72.375  -58.593 1.00 62.07  ? 59  ARG H2 NH2 1 
ATOM 5649 N N   . TYR C 3 60  ? 103.908 73.298  -54.554 1.00 56.96  ? 60  TYR H2 N   1 
ATOM 5650 C CA  . TYR C 3 60  ? 105.188 73.732  -55.075 1.00 55.80  ? 60  TYR H2 CA  1 
ATOM 5651 C C   . TYR C 3 60  ? 105.167 73.527  -56.575 1.00 55.72  ? 60  TYR H2 C   1 
ATOM 5652 O O   . TYR C 3 60  ? 104.127 73.229  -57.164 1.00 56.28  ? 60  TYR H2 O   1 
ATOM 5653 C CB  . TYR C 3 60  ? 106.359 72.953  -54.477 1.00 55.69  ? 60  TYR H2 CB  1 
ATOM 5654 C CG  . TYR C 3 60  ? 106.432 72.907  -52.977 1.00 55.65  ? 60  TYR H2 CG  1 
ATOM 5655 C CD1 . TYR C 3 60  ? 106.112 71.750  -52.296 1.00 55.41  ? 60  TYR H2 CD1 1 
ATOM 5656 C CD2 . TYR C 3 60  ? 106.861 73.995  -52.249 1.00 55.82  ? 60  TYR H2 CD2 1 
ATOM 5657 C CE1 . TYR C 3 60  ? 106.193 71.685  -50.933 1.00 55.60  ? 60  TYR H2 CE1 1 
ATOM 5658 C CE2 . TYR C 3 60  ? 106.939 73.941  -50.886 1.00 56.02  ? 60  TYR H2 CE2 1 
ATOM 5659 C CZ  . TYR C 3 60  ? 106.604 72.781  -50.235 1.00 55.01  ? 60  TYR H2 CZ  1 
ATOM 5660 O OH  . TYR C 3 60  ? 106.684 72.713  -48.868 1.00 54.72  ? 60  TYR H2 OH  1 
ATOM 5661 N N   . ASN C 3 61  ? 106.321 73.680  -57.201 1.00 54.74  ? 61  ASN H2 N   1 
ATOM 5662 C CA  . ASN C 3 61  ? 106.529 73.092  -58.508 1.00 53.96  ? 61  ASN H2 CA  1 
ATOM 5663 C C   . ASN C 3 61  ? 107.593 72.012  -58.409 1.00 54.26  ? 61  ASN H2 C   1 
ATOM 5664 O O   . ASN C 3 61  ? 108.182 71.780  -57.354 1.00 53.96  ? 61  ASN H2 O   1 
ATOM 5665 C CB  . ASN C 3 61  ? 106.888 74.139  -59.560 1.00 53.56  ? 61  ASN H2 CB  1 
ATOM 5666 C CG  . ASN C 3 61  ? 107.873 75.128  -59.068 1.00 53.93  ? 61  ASN H2 CG  1 
ATOM 5667 O OD1 . ASN C 3 61  ? 108.125 75.210  -57.875 1.00 54.50  ? 61  ASN H2 OD1 1 
ATOM 5668 N ND2 . ASN C 3 61  ? 108.422 75.919  -59.974 1.00 53.59  ? 61  ASN H2 ND2 1 
ATOM 5669 N N   . GLU C 3 62  ? 107.809 71.334  -59.530 1.00 54.19  ? 62  GLU H2 N   1 
ATOM 5670 C CA  . GLU C 3 62  ? 108.548 70.082  -59.521 1.00 54.07  ? 62  GLU H2 CA  1 
ATOM 5671 C C   . GLU C 3 62  ? 110.047 70.305  -59.415 1.00 53.63  ? 62  GLU H2 C   1 
ATOM 5672 O O   . GLU C 3 62  ? 110.770 69.389  -59.013 1.00 52.74  ? 62  GLU H2 O   1 
ATOM 5673 C CB  . GLU C 3 62  ? 108.239 69.254  -60.779 1.00 55.70  ? 62  GLU H2 CB  1 
ATOM 5674 C CG  . GLU C 3 62  ? 106.788 68.735  -60.974 1.00 57.33  ? 62  GLU H2 CG  1 
ATOM 5675 C CD  . GLU C 3 62  ? 105.724 69.818  -61.136 1.00 59.10  ? 62  GLU H2 CD  1 
ATOM 5676 O OE1 . GLU C 3 62  ? 105.937 70.749  -61.938 1.00 59.99  ? 62  GLU H2 OE1 1 
ATOM 5677 O OE2 . GLU C 3 62  ? 104.686 69.746  -60.449 1.00 59.64  ? 62  GLU H2 OE2 1 
ATOM 5678 N N   . LYS C 3 63  ? 110.529 71.492  -59.762 1.00 52.75  ? 63  LYS H2 N   1 
ATOM 5679 C CA  . LYS C 3 63  ? 111.943 71.789  -59.629 1.00 52.48  ? 63  LYS H2 CA  1 
ATOM 5680 C C   . LYS C 3 63  ? 112.305 72.289  -58.243 1.00 52.71  ? 63  LYS H2 C   1 
ATOM 5681 O O   . LYS C 3 63  ? 113.468 72.626  -58.009 1.00 53.49  ? 63  LYS H2 O   1 
ATOM 5682 C CB  . LYS C 3 63  ? 112.366 72.819  -60.675 1.00 51.38  ? 63  LYS H2 CB  1 
ATOM 5683 C CG  . LYS C 3 63  ? 111.303 73.842  -60.987 1.00 50.10  ? 63  LYS H2 CG  1 
ATOM 5684 C CD  . LYS C 3 63  ? 111.843 74.971  -61.835 1.00 49.20  ? 63  LYS H2 CD  1 
ATOM 5685 C CE  . LYS C 3 63  ? 111.879 74.585  -63.292 1.00 48.86  ? 63  LYS H2 CE  1 
ATOM 5686 N NZ  . LYS C 3 63  ? 112.145 75.759  -64.160 1.00 48.79  ? 63  LYS H2 NZ  1 
ATOM 5687 N N   . PHE C 3 64  ? 111.346 72.349  -57.327 1.00 53.55  ? 64  PHE H2 N   1 
ATOM 5688 C CA  . PHE C 3 64  ? 111.575 72.858  -55.984 1.00 54.21  ? 64  PHE H2 CA  1 
ATOM 5689 C C   . PHE C 3 64  ? 111.016 71.883  -54.963 1.00 56.82  ? 64  PHE H2 C   1 
ATOM 5690 O O   . PHE C 3 64  ? 110.493 72.276  -53.921 1.00 56.01  ? 64  PHE H2 O   1 
ATOM 5691 C CB  . PHE C 3 64  ? 110.935 74.230  -55.795 1.00 52.71  ? 64  PHE H2 CB  1 
ATOM 5692 C CG  . PHE C 3 64  ? 111.600 75.331  -56.558 1.00 50.60  ? 64  PHE H2 CG  1 
ATOM 5693 C CD1 . PHE C 3 64  ? 111.274 75.572  -57.876 1.00 49.30  ? 64  PHE H2 CD1 1 
ATOM 5694 C CD2 . PHE C 3 64  ? 112.529 76.143  -55.949 1.00 49.65  ? 64  PHE H2 CD2 1 
ATOM 5695 C CE1 . PHE C 3 64  ? 111.867 76.583  -58.578 1.00 49.25  ? 64  PHE H2 CE1 1 
ATOM 5696 C CE2 . PHE C 3 64  ? 113.133 77.159  -56.647 1.00 48.06  ? 64  PHE H2 CE2 1 
ATOM 5697 C CZ  . PHE C 3 64  ? 112.799 77.378  -57.965 1.00 48.54  ? 64  PHE H2 CZ  1 
ATOM 5698 N N   . LYS C 3 65  ? 111.110 70.586  -55.254 1.00 58.74  ? 65  LYS H2 N   1 
ATOM 5699 C CA  . LYS C 3 65  ? 110.417 69.613  -54.417 1.00 60.88  ? 65  LYS H2 CA  1 
ATOM 5700 C C   . LYS C 3 65  ? 111.141 69.386  -53.099 1.00 61.31  ? 65  LYS H2 C   1 
ATOM 5701 O O   . LYS C 3 65  ? 110.621 69.725  -52.030 1.00 62.23  ? 65  LYS H2 O   1 
ATOM 5702 C CB  . LYS C 3 65  ? 110.257 68.284  -55.162 1.00 62.02  ? 65  LYS H2 CB  1 
ATOM 5703 C CG  . LYS C 3 65  ? 109.181 68.261  -56.251 1.00 63.80  ? 65  LYS H2 CG  1 
ATOM 5704 C CD  . LYS C 3 65  ? 107.773 68.663  -55.789 1.00 64.17  ? 65  LYS H2 CD  1 
ATOM 5705 C CE  . LYS C 3 65  ? 107.274 67.901  -54.564 1.00 65.01  ? 65  LYS H2 CE  1 
ATOM 5706 N NZ  . LYS C 3 65  ? 106.177 68.648  -53.905 1.00 65.12  ? 65  LYS H2 NZ  1 
ATOM 5707 N N   . GLY C 3 66  ? 112.349 68.840  -53.157 1.00 61.49  ? 66  GLY H2 N   1 
ATOM 5708 C CA  . GLY C 3 66  ? 113.134 68.645  -51.959 1.00 61.37  ? 66  GLY H2 CA  1 
ATOM 5709 C C   . GLY C 3 66  ? 114.081 69.802  -51.762 1.00 61.53  ? 66  GLY H2 C   1 
ATOM 5710 O O   . GLY C 3 66  ? 114.917 69.795  -50.856 1.00 61.63  ? 66  GLY H2 O   1 
ATOM 5711 N N   . LYS C 3 67  ? 113.940 70.817  -52.605 1.00 61.70  ? 67  LYS H2 N   1 
ATOM 5712 C CA  . LYS C 3 67  ? 114.810 71.977  -52.545 1.00 61.51  ? 67  LYS H2 CA  1 
ATOM 5713 C C   . LYS C 3 67  ? 114.403 72.975  -51.473 1.00 61.16  ? 67  LYS H2 C   1 
ATOM 5714 O O   . LYS C 3 67  ? 115.287 73.568  -50.857 1.00 61.20  ? 67  LYS H2 O   1 
ATOM 5715 C CB  . LYS C 3 67  ? 114.845 72.661  -53.912 1.00 61.76  ? 67  LYS H2 CB  1 
ATOM 5716 C CG  . LYS C 3 67  ? 115.952 73.690  -54.102 1.00 62.54  ? 67  LYS H2 CG  1 
ATOM 5717 C CD  . LYS C 3 67  ? 115.384 75.093  -54.076 1.00 62.86  ? 67  LYS H2 CD  1 
ATOM 5718 C CE  . LYS C 3 67  ? 116.401 76.119  -54.494 1.00 63.27  ? 67  LYS H2 CE  1 
ATOM 5719 N NZ  . LYS C 3 67  ? 115.789 77.472  -54.543 1.00 63.45  ? 67  LYS H2 NZ  1 
ATOM 5720 N N   . ALA C 3 68  ? 113.111 73.164  -51.218 1.00 61.03  ? 68  ALA H2 N   1 
ATOM 5721 C CA  . ALA C 3 68  ? 112.665 74.169  -50.257 1.00 61.04  ? 68  ALA H2 CA  1 
ATOM 5722 C C   . ALA C 3 68  ? 111.320 73.755  -49.684 1.00 61.55  ? 68  ALA H2 C   1 
ATOM 5723 O O   . ALA C 3 68  ? 110.459 73.274  -50.424 1.00 62.82  ? 68  ALA H2 O   1 
ATOM 5724 C CB  . ALA C 3 68  ? 112.563 75.546  -50.909 1.00 60.71  ? 68  ALA H2 CB  1 
ATOM 5725 N N   . THR C 3 69  ? 111.146 73.934  -48.371 1.00 61.47  ? 69  THR H2 N   1 
ATOM 5726 C CA  . THR C 3 69  ? 109.907 73.606  -47.669 1.00 61.61  ? 69  THR H2 CA  1 
ATOM 5727 C C   . THR C 3 69  ? 109.373 74.873  -47.019 1.00 61.92  ? 69  THR H2 C   1 
ATOM 5728 O O   . THR C 3 69  ? 110.095 75.538  -46.272 1.00 62.66  ? 69  THR H2 O   1 
ATOM 5729 C CB  . THR C 3 69  ? 110.121 72.535  -46.602 1.00 61.70  ? 69  THR H2 CB  1 
ATOM 5730 O OG1 . THR C 3 69  ? 110.595 73.154  -45.404 1.00 60.78  ? 69  THR H2 OG1 1 
ATOM 5731 C CG2 . THR C 3 69  ? 111.127 71.491  -47.052 1.00 60.88  ? 69  THR H2 CG2 1 
ATOM 5732 N N   . LEU C 3 70  ? 108.112 75.191  -47.277 1.00 62.20  ? 70  LEU H2 N   1 
ATOM 5733 C CA  . LEU C 3 70  ? 107.505 76.389  -46.726 1.00 62.78  ? 70  LEU H2 CA  1 
ATOM 5734 C C   . LEU C 3 70  ? 106.753 76.066  -45.443 1.00 63.62  ? 70  LEU H2 C   1 
ATOM 5735 O O   . LEU C 3 70  ? 106.033 75.072  -45.352 1.00 64.65  ? 70  LEU H2 O   1 
ATOM 5736 C CB  . LEU C 3 70  ? 106.530 77.003  -47.720 1.00 62.18  ? 70  LEU H2 CB  1 
ATOM 5737 C CG  . LEU C 3 70  ? 106.974 77.183  -49.162 1.00 61.49  ? 70  LEU H2 CG  1 
ATOM 5738 C CD1 . LEU C 3 70  ? 105.848 77.804  -49.919 1.00 60.38  ? 70  LEU H2 CD1 1 
ATOM 5739 C CD2 . LEU C 3 70  ? 108.203 78.035  -49.248 1.00 61.07  ? 70  LEU H2 CD2 1 
ATOM 5740 N N   . THR C 3 71  ? 106.941 76.906  -44.432 1.00 63.86  ? 71  THR H2 N   1 
ATOM 5741 C CA  . THR C 3 71  ? 106.103 76.840  -43.242 1.00 64.65  ? 71  THR H2 CA  1 
ATOM 5742 C C   . THR C 3 71  ? 105.561 78.231  -42.971 1.00 65.33  ? 71  THR H2 C   1 
ATOM 5743 O O   . THR C 3 71  ? 105.932 79.205  -43.626 1.00 65.70  ? 71  THR H2 O   1 
ATOM 5744 C CB  . THR C 3 71  ? 106.852 76.330  -42.002 1.00 64.90  ? 71  THR H2 CB  1 
ATOM 5745 O OG1 . THR C 3 71  ? 107.866 77.263  -41.628 1.00 64.96  ? 71  THR H2 OG1 1 
ATOM 5746 C CG2 . THR C 3 71  ? 107.489 74.977  -42.243 1.00 64.97  ? 71  THR H2 CG2 1 
ATOM 5747 N N   . THR C 3 72  ? 104.661 78.307  -42.003 1.00 65.68  ? 72  THR H2 N   1 
ATOM 5748 C CA  . THR C 3 72  ? 104.206 79.568  -41.449 1.00 66.48  ? 72  THR H2 CA  1 
ATOM 5749 C C   . THR C 3 72  ? 104.195 79.487  -39.935 1.00 66.77  ? 72  THR H2 C   1 
ATOM 5750 O O   . THR C 3 72  ? 104.159 78.407  -39.345 1.00 66.97  ? 72  THR H2 O   1 
ATOM 5751 C CB  . THR C 3 72  ? 102.806 79.942  -41.939 1.00 66.76  ? 72  THR H2 CB  1 
ATOM 5752 O OG1 . THR C 3 72  ? 102.003 78.764  -42.051 1.00 67.68  ? 72  THR H2 OG1 1 
ATOM 5753 C CG2 . THR C 3 72  ? 102.871 80.659  -43.261 1.00 67.23  ? 72  THR H2 CG2 1 
ATOM 5754 N N   . ASP C 3 73  ? 104.227 80.651  -39.315 1.00 66.99  ? 73  ASP H2 N   1 
ATOM 5755 C CA  . ASP C 3 73  ? 104.060 80.782  -37.880 1.00 66.58  ? 73  ASP H2 CA  1 
ATOM 5756 C C   . ASP C 3 73  ? 102.785 81.582  -37.675 1.00 66.32  ? 73  ASP H2 C   1 
ATOM 5757 O O   . ASP C 3 73  ? 102.774 82.801  -37.867 1.00 66.17  ? 73  ASP H2 O   1 
ATOM 5758 C CB  . ASP C 3 73  ? 105.275 81.462  -37.256 1.00 67.30  ? 73  ASP H2 CB  1 
ATOM 5759 C CG  . ASP C 3 73  ? 105.145 81.658  -35.758 1.00 68.42  ? 73  ASP H2 CG  1 
ATOM 5760 O OD1 . ASP C 3 73  ? 105.890 82.501  -35.215 1.00 68.47  ? 73  ASP H2 OD1 1 
ATOM 5761 O OD2 . ASP C 3 73  ? 104.334 80.959  -35.116 1.00 68.59  ? 73  ASP H2 OD2 1 
ATOM 5762 N N   . LYS C 3 74  ? 101.712 80.890  -37.314 1.00 65.99  ? 74  LYS H2 N   1 
ATOM 5763 C CA  . LYS C 3 74  ? 100.471 81.554  -36.956 1.00 65.63  ? 74  LYS H2 CA  1 
ATOM 5764 C C   . LYS C 3 74  ? 100.662 82.356  -35.673 1.00 65.19  ? 74  LYS H2 C   1 
ATOM 5765 O O   . LYS C 3 74  ? 101.574 82.090  -34.882 1.00 64.17  ? 74  LYS H2 O   1 
ATOM 5766 C CB  . LYS C 3 74  ? 99.356  80.526  -36.777 1.00 66.51  ? 74  LYS H2 CB  1 
ATOM 5767 C CG  . LYS C 3 74  ? 98.766  80.010  -38.074 1.00 67.88  ? 74  LYS H2 CG  1 
ATOM 5768 C CD  . LYS C 3 74  ? 97.499  79.195  -37.827 1.00 68.63  ? 74  LYS H2 CD  1 
ATOM 5769 C CE  . LYS C 3 74  ? 96.285  80.085  -37.674 1.00 68.13  ? 74  LYS H2 CE  1 
ATOM 5770 N NZ  . LYS C 3 74  ? 95.156  79.355  -37.038 1.00 68.51  ? 74  LYS H2 NZ  1 
ATOM 5771 N N   . SER C 3 75  ? 99.821  83.382  -35.508 1.00 64.58  ? 75  SER H2 N   1 
ATOM 5772 C CA  . SER C 3 75  ? 99.815  84.316  -34.373 1.00 64.07  ? 75  SER H2 CA  1 
ATOM 5773 C C   . SER C 3 75  ? 101.099 85.138  -34.261 1.00 63.30  ? 75  SER H2 C   1 
ATOM 5774 O O   . SER C 3 75  ? 101.340 85.774  -33.231 1.00 63.13  ? 75  SER H2 O   1 
ATOM 5775 C CB  . SER C 3 75  ? 99.535  83.609  -33.039 1.00 64.98  ? 75  SER H2 CB  1 
ATOM 5776 O OG  . SER C 3 75  ? 100.684 82.902  -32.605 1.00 65.74  ? 75  SER H2 OG  1 
ATOM 5777 N N   . SER C 3 76  ? 101.931 85.143  -35.301 1.00 61.88  ? 76  SER H2 N   1 
ATOM 5778 C CA  . SER C 3 76  ? 103.025 86.087  -35.427 1.00 60.34  ? 76  SER H2 CA  1 
ATOM 5779 C C   . SER C 3 76  ? 103.127 86.666  -36.825 1.00 59.11  ? 76  SER H2 C   1 
ATOM 5780 O O   . SER C 3 76  ? 103.945 87.567  -37.038 1.00 58.65  ? 76  SER H2 O   1 
ATOM 5781 C CB  . SER C 3 76  ? 104.360 85.431  -35.059 1.00 59.59  ? 76  SER H2 CB  1 
ATOM 5782 O OG  . SER C 3 76  ? 104.949 84.831  -36.194 1.00 58.71  ? 76  SER H2 OG  1 
ATOM 5783 N N   . SER C 3 77  ? 102.341 86.148  -37.778 1.00 57.90  ? 77  SER H2 N   1 
ATOM 5784 C CA  . SER C 3 77  ? 102.162 86.690  -39.126 1.00 56.49  ? 77  SER H2 CA  1 
ATOM 5785 C C   . SER C 3 77  ? 103.461 86.697  -39.923 1.00 54.99  ? 77  SER H2 C   1 
ATOM 5786 O O   . SER C 3 77  ? 103.790 87.667  -40.603 1.00 55.26  ? 77  SER H2 O   1 
ATOM 5787 C CB  . SER C 3 77  ? 101.536 88.083  -39.087 1.00 55.82  ? 77  SER H2 CB  1 
ATOM 5788 O OG  . SER C 3 77  ? 100.390 88.081  -38.258 1.00 57.94  ? 77  SER H2 OG  1 
ATOM 5789 N N   . THR C 3 78  ? 104.191 85.588  -39.862 1.00 53.41  ? 78  THR H2 N   1 
ATOM 5790 C CA  . THR C 3 78  ? 105.419 85.471  -40.627 1.00 52.37  ? 78  THR H2 CA  1 
ATOM 5791 C C   . THR C 3 78  ? 105.470 84.111  -41.307 1.00 51.37  ? 78  THR H2 C   1 
ATOM 5792 O O   . THR C 3 78  ? 104.898 83.132  -40.824 1.00 50.96  ? 78  THR H2 O   1 
ATOM 5793 C CB  . THR C 3 78  ? 106.655 85.727  -39.740 1.00 53.16  ? 78  THR H2 CB  1 
ATOM 5794 O OG1 . THR C 3 78  ? 107.797 85.999  -40.561 1.00 54.69  ? 78  THR H2 OG1 1 
ATOM 5795 C CG2 . THR C 3 78  ? 106.957 84.567  -38.822 1.00 52.29  ? 78  THR H2 CG2 1 
ATOM 5796 N N   . ALA C 3 79  ? 106.111 84.079  -42.469 1.00 49.83  ? 79  ALA H2 N   1 
ATOM 5797 C CA  . ALA C 3 79  ? 106.266 82.871  -43.260 1.00 48.21  ? 79  ALA H2 CA  1 
ATOM 5798 C C   . ALA C 3 79  ? 107.723 82.442  -43.229 1.00 47.45  ? 79  ALA H2 C   1 
ATOM 5799 O O   . ALA C 3 79  ? 108.585 83.167  -42.734 1.00 46.56  ? 79  ALA H2 O   1 
ATOM 5800 C CB  . ALA C 3 79  ? 105.804 83.095  -44.699 1.00 47.32  ? 79  ALA H2 CB  1 
ATOM 5801 N N   . TYR C 3 80  ? 108.006 81.251  -43.749 1.00 47.28  ? 80  TYR H2 N   1 
ATOM 5802 C CA  . TYR C 3 80  ? 109.361 80.720  -43.745 1.00 48.66  ? 80  TYR H2 CA  1 
ATOM 5803 C C   . TYR C 3 80  ? 109.616 79.890  -44.991 1.00 49.80  ? 80  TYR H2 C   1 
ATOM 5804 O O   . TYR C 3 80  ? 108.684 79.498  -45.694 1.00 50.70  ? 80  TYR H2 O   1 
ATOM 5805 C CB  . TYR C 3 80  ? 109.624 79.873  -42.505 1.00 48.88  ? 80  TYR H2 CB  1 
ATOM 5806 C CG  . TYR C 3 80  ? 109.627 80.660  -41.224 1.00 48.47  ? 80  TYR H2 CG  1 
ATOM 5807 C CD1 . TYR C 3 80  ? 108.554 80.606  -40.357 1.00 49.51  ? 80  TYR H2 CD1 1 
ATOM 5808 C CD2 . TYR C 3 80  ? 110.691 81.475  -40.897 1.00 49.02  ? 80  TYR H2 CD2 1 
ATOM 5809 C CE1 . TYR C 3 80  ? 108.550 81.328  -39.193 1.00 50.14  ? 80  TYR H2 CE1 1 
ATOM 5810 C CE2 . TYR C 3 80  ? 110.699 82.198  -39.734 1.00 48.23  ? 80  TYR H2 CE2 1 
ATOM 5811 C CZ  . TYR C 3 80  ? 109.622 82.124  -38.890 1.00 49.68  ? 80  TYR H2 CZ  1 
ATOM 5812 O OH  . TYR C 3 80  ? 109.630 82.850  -37.727 1.00 50.21  ? 80  TYR H2 OH  1 
ATOM 5813 N N   . GLN C 3 81  ? 110.895 79.626  -45.260 1.00 51.17  ? 81  GLN H2 N   1 
ATOM 5814 C CA  . GLN C 3 81  ? 111.329 78.804  -46.390 1.00 52.54  ? 81  GLN H2 CA  1 
ATOM 5815 C C   . GLN C 3 81  ? 112.745 78.303  -46.116 1.00 54.25  ? 81  GLN H2 C   1 
ATOM 5816 O O   . GLN C 3 81  ? 113.652 79.110  -45.911 1.00 55.44  ? 81  GLN H2 O   1 
ATOM 5817 C CB  . GLN C 3 81  ? 111.280 79.596  -47.683 1.00 52.18  ? 81  GLN H2 CB  1 
ATOM 5818 C CG  . GLN C 3 81  ? 111.868 78.847  -48.836 1.00 49.56  ? 81  GLN H2 CG  1 
ATOM 5819 C CD  . GLN C 3 81  ? 111.696 79.572  -50.129 1.00 47.09  ? 81  GLN H2 CD  1 
ATOM 5820 O OE1 . GLN C 3 81  ? 111.216 80.697  -50.159 1.00 44.81  ? 81  GLN H2 OE1 1 
ATOM 5821 N NE2 . GLN C 3 81  ? 112.090 78.934  -51.214 1.00 48.30  ? 81  GLN H2 NE2 1 
ATOM 5822 N N   . LEU C 3 82  ? 112.956 76.982  -46.157 1.00 55.15  ? 82  LEU H2 N   1 
ATOM 5823 C CA  . LEU C 3 82  ? 114.231 76.432  -45.703 1.00 56.37  ? 82  LEU H2 CA  1 
ATOM 5824 C C   . LEU C 3 82  ? 115.357 76.569  -46.721 1.00 56.95  ? 82  LEU H2 C   1 
ATOM 5825 O O   . LEU C 3 82  ? 116.475 76.924  -46.335 1.00 58.19  ? 82  LEU H2 O   1 
ATOM 5826 C CB  . LEU C 3 82  ? 114.094 74.963  -45.317 1.00 58.15  ? 82  LEU H2 CB  1 
ATOM 5827 C CG  . LEU C 3 82  ? 113.544 74.662  -43.929 1.00 58.29  ? 82  LEU H2 CG  1 
ATOM 5828 C CD1 . LEU C 3 82  ? 113.446 73.164  -43.732 1.00 57.93  ? 82  LEU H2 CD1 1 
ATOM 5829 C CD2 . LEU C 3 82  ? 114.458 75.268  -42.890 1.00 59.65  ? 82  LEU H2 CD2 1 
ATOM 5830 N N   . ASN C 3 83  ? 115.099 76.247  -47.993 1.00 57.21  ? 83  ASN H2 N   1 
ATOM 5831 C CA  . ASN C 3 83  ? 116.103 76.186  -49.067 1.00 57.61  ? 83  ASN H2 CA  1 
ATOM 5832 C C   . ASN C 3 83  ? 117.231 75.213  -48.708 1.00 58.55  ? 83  ASN H2 C   1 
ATOM 5833 O O   . ASN C 3 83  ? 118.367 75.601  -48.467 1.00 58.45  ? 83  ASN H2 O   1 
ATOM 5834 C CB  . ASN C 3 83  ? 116.674 77.564  -49.415 1.00 57.11  ? 83  ASN H2 CB  1 
ATOM 5835 C CG  . ASN C 3 83  ? 115.753 78.364  -50.270 1.00 58.01  ? 83  ASN H2 CG  1 
ATOM 5836 O OD1 . ASN C 3 83  ? 115.084 77.833  -51.147 1.00 57.06  ? 83  ASN H2 OD1 1 
ATOM 5837 N ND2 . ASN C 3 83  ? 115.711 79.658  -50.027 1.00 57.59  ? 83  ASN H2 ND2 1 
ATOM 5838 N N   . ARG C 3 84  ? 116.871 73.933  -48.675 1.00 59.49  ? 84  ARG H2 N   1 
ATOM 5839 C CA  . ARG C 3 84  ? 117.713 72.920  -48.044 1.00 60.74  ? 84  ARG H2 CA  1 
ATOM 5840 C C   . ARG C 3 84  ? 118.995 72.628  -48.820 1.00 60.70  ? 84  ARG H2 C   1 
ATOM 5841 O O   . ARG C 3 84  ? 120.058 72.444  -48.220 1.00 61.42  ? 84  ARG H2 O   1 
ATOM 5842 C CB  . ARG C 3 84  ? 116.909 71.637  -47.843 1.00 61.35  ? 84  ARG H2 CB  1 
ATOM 5843 C CG  . ARG C 3 84  ? 116.002 71.665  -46.625 1.00 61.84  ? 84  ARG H2 CG  1 
ATOM 5844 C CD  . ARG C 3 84  ? 116.836 71.647  -45.356 1.00 62.86  ? 84  ARG H2 CD  1 
ATOM 5845 N NE  . ARG C 3 84  ? 116.984 72.976  -44.772 1.00 62.65  ? 84  ARG H2 NE  1 
ATOM 5846 C CZ  . ARG C 3 84  ? 118.031 73.368  -44.056 1.00 62.93  ? 84  ARG H2 CZ  1 
ATOM 5847 N NH1 . ARG C 3 84  ? 119.044 72.539  -43.853 1.00 61.89  ? 84  ARG H2 NH1 1 
ATOM 5848 N NH2 . ARG C 3 84  ? 118.073 74.598  -43.563 1.00 63.02  ? 84  ARG H2 NH2 1 
ATOM 5849 N N   . LEU C 3 85  ? 118.921 72.564  -50.151 1.00 61.30  ? 85  LEU H2 N   1 
ATOM 5850 C CA  . LEU C 3 85  ? 120.107 72.172  -50.912 1.00 61.88  ? 85  LEU H2 CA  1 
ATOM 5851 C C   . LEU C 3 85  ? 121.131 73.299  -50.975 1.00 61.58  ? 85  LEU H2 C   1 
ATOM 5852 O O   . LEU C 3 85  ? 122.230 73.168  -50.424 1.00 61.45  ? 85  LEU H2 O   1 
ATOM 5853 C CB  . LEU C 3 85  ? 119.711 71.724  -52.320 1.00 62.86  ? 85  LEU H2 CB  1 
ATOM 5854 C CG  . LEU C 3 85  ? 118.448 70.867  -52.425 1.00 63.82  ? 85  LEU H2 CG  1 
ATOM 5855 C CD1 . LEU C 3 85  ? 118.090 70.624  -53.880 1.00 63.27  ? 85  LEU H2 CD1 1 
ATOM 5856 C CD2 . LEU C 3 85  ? 118.614 69.544  -51.677 1.00 63.58  ? 85  LEU H2 CD2 1 
ATOM 5857 N N   . THR C 3 86  ? 120.764 74.413  -51.624 1.00 62.05  ? 86  THR H2 N   1 
ATOM 5858 C CA  . THR C 3 86  ? 121.520 75.669  -51.674 1.00 60.70  ? 86  THR H2 CA  1 
ATOM 5859 C C   . THR C 3 86  ? 122.926 75.437  -52.246 1.00 59.28  ? 86  THR H2 C   1 
ATOM 5860 O O   . THR C 3 86  ? 123.939 75.463  -51.550 1.00 58.17  ? 86  THR H2 O   1 
ATOM 5861 C CB  . THR C 3 86  ? 121.546 76.350  -50.297 1.00 61.53  ? 86  THR H2 CB  1 
ATOM 5862 O OG1 . THR C 3 86  ? 120.216 76.403  -49.783 1.00 61.73  ? 86  THR H2 OG1 1 
ATOM 5863 C CG2 . THR C 3 86  ? 121.999 77.783  -50.412 1.00 60.98  ? 86  THR H2 CG2 1 
ATOM 5864 N N   . SER C 3 87  ? 122.943 75.119  -53.538 1.00 58.47  ? 87  SER H2 N   1 
ATOM 5865 C CA  . SER C 3 87  ? 124.190 74.774  -54.209 1.00 57.29  ? 87  SER H2 CA  1 
ATOM 5866 C C   . SER C 3 87  ? 124.705 75.910  -55.087 1.00 56.47  ? 87  SER H2 C   1 
ATOM 5867 O O   . SER C 3 87  ? 125.860 76.325  -54.963 1.00 54.81  ? 87  SER H2 O   1 
ATOM 5868 C CB  . SER C 3 87  ? 123.997 73.503  -55.037 1.00 57.52  ? 87  SER H2 CB  1 
ATOM 5869 O OG  . SER C 3 87  ? 123.462 73.803  -56.312 1.00 57.47  ? 87  SER H2 OG  1 
ATOM 5870 N N   . GLU C 3 88  ? 123.865 76.416  -55.979 1.00 56.60  ? 88  GLU H2 N   1 
ATOM 5871 C CA  . GLU C 3 88  ? 124.252 77.460  -56.921 1.00 55.00  ? 88  GLU H2 CA  1 
ATOM 5872 C C   . GLU C 3 88  ? 123.145 78.496  -57.040 1.00 53.68  ? 88  GLU H2 C   1 
ATOM 5873 O O   . GLU C 3 88  ? 123.138 79.324  -57.956 1.00 53.48  ? 88  GLU H2 O   1 
ATOM 5874 C CB  . GLU C 3 88  ? 124.586 76.854  -58.283 1.00 56.46  ? 88  GLU H2 CB  1 
ATOM 5875 C CG  . GLU C 3 88  ? 123.483 75.949  -58.827 1.00 57.73  ? 88  GLU H2 CG  1 
ATOM 5876 C CD  . GLU C 3 88  ? 122.448 76.671  -59.660 1.00 59.10  ? 88  GLU H2 CD  1 
ATOM 5877 O OE1 . GLU C 3 88  ? 122.778 77.708  -60.269 1.00 59.44  ? 88  GLU H2 OE1 1 
ATOM 5878 O OE2 . GLU C 3 88  ? 121.289 76.218  -59.673 1.00 59.16  ? 88  GLU H2 OE2 1 
ATOM 5879 N N   . ASP C 3 89  ? 122.219 78.495  -56.083 1.00 51.09  ? 89  ASP H2 N   1 
ATOM 5880 C CA  . ASP C 3 89  ? 120.927 79.149  -56.231 1.00 49.23  ? 89  ASP H2 CA  1 
ATOM 5881 C C   . ASP C 3 89  ? 120.920 80.574  -55.698 1.00 46.76  ? 89  ASP H2 C   1 
ATOM 5882 O O   . ASP C 3 89  ? 119.912 81.020  -55.138 1.00 46.46  ? 89  ASP H2 O   1 
ATOM 5883 C CB  . ASP C 3 89  ? 119.846 78.307  -55.555 1.00 50.16  ? 89  ASP H2 CB  1 
ATOM 5884 C CG  . ASP C 3 89  ? 120.148 78.020  -54.097 1.00 51.55  ? 89  ASP H2 CG  1 
ATOM 5885 O OD1 . ASP C 3 89  ? 121.228 78.401  -53.605 1.00 52.06  ? 89  ASP H2 OD1 1 
ATOM 5886 O OD2 . ASP C 3 89  ? 119.295 77.398  -53.434 1.00 52.66  ? 89  ASP H2 OD2 1 
ATOM 5887 N N   . SER C 3 90  ? 122.034 81.283  -55.838 1.00 43.93  ? 90  SER H2 N   1 
ATOM 5888 C CA  . SER C 3 90  ? 122.166 82.658  -55.380 1.00 42.36  ? 90  SER H2 CA  1 
ATOM 5889 C C   . SER C 3 90  ? 121.249 83.553  -56.197 1.00 40.89  ? 90  SER H2 C   1 
ATOM 5890 O O   . SER C 3 90  ? 121.519 83.842  -57.362 1.00 40.48  ? 90  SER H2 O   1 
ATOM 5891 C CB  . SER C 3 90  ? 123.613 83.111  -55.506 1.00 42.35  ? 90  SER H2 CB  1 
ATOM 5892 O OG  . SER C 3 90  ? 124.400 82.579  -54.460 1.00 44.93  ? 90  SER H2 OG  1 
ATOM 5893 N N   . ALA C 3 91  ? 120.163 84.005  -55.583 1.00 38.80  ? 91  ALA H2 N   1 
ATOM 5894 C CA  . ALA C 3 91  ? 119.190 84.844  -56.264 1.00 35.77  ? 91  ALA H2 CA  1 
ATOM 5895 C C   . ALA C 3 91  ? 118.477 85.691  -55.225 1.00 33.11  ? 91  ALA H2 C   1 
ATOM 5896 O O   . ALA C 3 91  ? 118.805 85.654  -54.036 1.00 32.48  ? 91  ALA H2 O   1 
ATOM 5897 C CB  . ALA C 3 91  ? 118.201 83.995  -57.055 1.00 38.15  ? 91  ALA H2 CB  1 
ATOM 5898 N N   . VAL C 3 92  ? 117.494 86.455  -55.677 1.00 29.44  ? 92  VAL H2 N   1 
ATOM 5899 C CA  . VAL C 3 92  ? 116.649 87.252  -54.804 1.00 29.16  ? 92  VAL H2 CA  1 
ATOM 5900 C C   . VAL C 3 92  ? 115.347 86.499  -54.602 1.00 29.45  ? 92  VAL H2 C   1 
ATOM 5901 O O   . VAL C 3 92  ? 114.680 86.127  -55.572 1.00 29.15  ? 92  VAL H2 O   1 
ATOM 5902 C CB  . VAL C 3 92  ? 116.401 88.647  -55.397 1.00 28.17  ? 92  VAL H2 CB  1 
ATOM 5903 C CG1 . VAL C 3 92  ? 115.365 89.389  -54.594 1.00 25.17  ? 92  VAL H2 CG1 1 
ATOM 5904 C CG2 . VAL C 3 92  ? 117.692 89.427  -55.425 1.00 25.38  ? 92  VAL H2 CG2 1 
ATOM 5905 N N   . TYR C 3 93  ? 114.992 86.260  -53.346 1.00 29.15  ? 93  TYR H2 N   1 
ATOM 5906 C CA  . TYR C 3 93  ? 113.835 85.446  -52.995 1.00 29.28  ? 93  TYR H2 CA  1 
ATOM 5907 C C   . TYR C 3 93  ? 112.723 86.374  -52.540 1.00 30.53  ? 93  TYR H2 C   1 
ATOM 5908 O O   . TYR C 3 93  ? 112.884 87.115  -51.568 1.00 30.11  ? 93  TYR H2 O   1 
ATOM 5909 C CB  . TYR C 3 93  ? 114.202 84.431  -51.921 1.00 26.90  ? 93  TYR H2 CB  1 
ATOM 5910 C CG  . TYR C 3 93  ? 114.904 83.226  -52.480 1.00 27.98  ? 93  TYR H2 CG  1 
ATOM 5911 C CD1 . TYR C 3 93  ? 114.245 82.018  -52.618 1.00 28.55  ? 93  TYR H2 CD1 1 
ATOM 5912 C CD2 . TYR C 3 93  ? 116.218 83.300  -52.895 1.00 27.82  ? 93  TYR H2 CD2 1 
ATOM 5913 C CE1 . TYR C 3 93  ? 114.887 80.915  -53.141 1.00 27.49  ? 93  TYR H2 CE1 1 
ATOM 5914 C CE2 . TYR C 3 93  ? 116.864 82.209  -53.413 1.00 28.71  ? 93  TYR H2 CE2 1 
ATOM 5915 C CZ  . TYR C 3 93  ? 116.196 81.022  -53.537 1.00 27.56  ? 93  TYR H2 CZ  1 
ATOM 5916 O OH  . TYR C 3 93  ? 116.845 79.932  -54.056 1.00 29.53  ? 93  TYR H2 OH  1 
ATOM 5917 N N   . PHE C 3 94  ? 111.602 86.339  -53.245 1.00 31.00  ? 94  PHE H2 N   1 
ATOM 5918 C CA  . PHE C 3 94  ? 110.530 87.299  -53.050 1.00 31.26  ? 94  PHE H2 CA  1 
ATOM 5919 C C   . PHE C 3 94  ? 109.378 86.674  -52.285 1.00 33.02  ? 94  PHE H2 C   1 
ATOM 5920 O O   . PHE C 3 94  ? 109.127 85.472  -52.388 1.00 31.17  ? 94  PHE H2 O   1 
ATOM 5921 C CB  . PHE C 3 94  ? 110.027 87.827  -54.386 1.00 28.95  ? 94  PHE H2 CB  1 
ATOM 5922 C CG  . PHE C 3 94  ? 110.787 88.999  -54.892 1.00 28.80  ? 94  PHE H2 CG  1 
ATOM 5923 C CD1 . PHE C 3 94  ? 110.708 90.215  -54.247 1.00 27.94  ? 94  PHE H2 CD1 1 
ATOM 5924 C CD2 . PHE C 3 94  ? 111.568 88.889  -56.020 1.00 29.87  ? 94  PHE H2 CD2 1 
ATOM 5925 C CE1 . PHE C 3 94  ? 111.399 91.299  -54.715 1.00 26.51  ? 94  PHE H2 CE1 1 
ATOM 5926 C CE2 . PHE C 3 94  ? 112.259 89.969  -56.492 1.00 30.55  ? 94  PHE H2 CE2 1 
ATOM 5927 C CZ  . PHE C 3 94  ? 112.176 91.176  -55.837 1.00 29.24  ? 94  PHE H2 CZ  1 
ATOM 5928 N N   . CYS C 3 95  ? 108.678 87.506  -51.537 1.00 34.72  ? 95  CYS H2 N   1 
ATOM 5929 C CA  . CYS C 3 95  ? 107.545 87.106  -50.722 1.00 36.97  ? 95  CYS H2 CA  1 
ATOM 5930 C C   . CYS C 3 95  ? 106.322 87.837  -51.251 1.00 36.56  ? 95  CYS H2 C   1 
ATOM 5931 O O   . CYS C 3 95  ? 106.155 89.032  -50.999 1.00 34.70  ? 95  CYS H2 O   1 
ATOM 5932 C CB  . CYS C 3 95  ? 107.831 87.462  -49.270 1.00 39.05  ? 95  CYS H2 CB  1 
ATOM 5933 S SG  . CYS C 3 95  ? 106.499 87.281  -48.146 1.00 49.79  ? 95  CYS H2 SG  1 
ATOM 5934 N N   . ALA C 3 96  ? 105.474 87.135  -51.986 1.00 36.32  ? 96  ALA H2 N   1 
ATOM 5935 C CA  . ALA C 3 96  ? 104.388 87.753  -52.727 1.00 37.11  ? 96  ALA H2 CA  1 
ATOM 5936 C C   . ALA C 3 96  ? 103.044 87.316  -52.165 1.00 38.27  ? 96  ALA H2 C   1 
ATOM 5937 O O   . ALA C 3 96  ? 102.896 86.187  -51.695 1.00 36.66  ? 96  ALA H2 O   1 
ATOM 5938 C CB  . ALA C 3 96  ? 104.476 87.395  -54.204 1.00 37.53  ? 96  ALA H2 CB  1 
ATOM 5939 N N   . ARG C 3 97  ? 102.078 88.220  -52.205 1.00 38.72  ? 97  ARG H2 N   1 
ATOM 5940 C CA  . ARG C 3 97  ? 100.723 87.980  -51.741 1.00 40.25  ? 97  ARG H2 CA  1 
ATOM 5941 C C   . ARG C 3 97  ? 99.764  88.432  -52.832 1.00 42.23  ? 97  ARG H2 C   1 
ATOM 5942 O O   . ARG C 3 97  ? 100.066 89.358  -53.584 1.00 41.33  ? 97  ARG H2 O   1 
ATOM 5943 C CB  . ARG C 3 97  ? 100.491 88.718  -50.421 1.00 40.04  ? 97  ARG H2 CB  1 
ATOM 5944 C CG  . ARG C 3 97  ? 99.107  88.713  -49.823 1.00 39.95  ? 97  ARG H2 CG  1 
ATOM 5945 C CD  . ARG C 3 97  ? 98.964  90.008  -49.069 1.00 37.22  ? 97  ARG H2 CD  1 
ATOM 5946 N NE  . ARG C 3 97  ? 97.619  90.384  -48.658 1.00 37.71  ? 97  ARG H2 NE  1 
ATOM 5947 C CZ  . ARG C 3 97  ? 96.682  90.861  -49.467 1.00 37.39  ? 97  ARG H2 CZ  1 
ATOM 5948 N NH1 . ARG C 3 97  ? 96.913  90.994  -50.753 1.00 35.45  ? 97  ARG H2 NH1 1 
ATOM 5949 N NH2 . ARG C 3 97  ? 95.508  91.210  -48.987 1.00 36.14  ? 97  ARG H2 NH2 1 
ATOM 5950 N N   . ARG C 3 98  ? 98.623  87.746  -52.932 1.00 43.98  ? 98  ARG H2 N   1 
ATOM 5951 C CA  . ARG C 3 98  ? 97.758  87.793  -54.104 1.00 46.54  ? 98  ARG H2 CA  1 
ATOM 5952 C C   . ARG C 3 98  ? 97.166  89.164  -54.402 1.00 48.45  ? 98  ARG H2 C   1 
ATOM 5953 O O   . ARG C 3 98  ? 97.517  89.771  -55.408 1.00 46.90  ? 98  ARG H2 O   1 
ATOM 5954 C CB  . ARG C 3 98  ? 96.629  86.780  -53.957 1.00 47.18  ? 98  ARG H2 CB  1 
ATOM 5955 C CG  . ARG C 3 98  ? 95.718  86.711  -55.164 1.00 48.05  ? 98  ARG H2 CG  1 
ATOM 5956 C CD  . ARG C 3 98  ? 94.679  85.622  -55.020 1.00 50.38  ? 98  ARG H2 CD  1 
ATOM 5957 N NE  . ARG C 3 98  ? 94.227  85.470  -53.646 1.00 51.46  ? 98  ARG H2 NE  1 
ATOM 5958 C CZ  . ARG C 3 98  ? 93.129  86.033  -53.160 1.00 52.41  ? 98  ARG H2 CZ  1 
ATOM 5959 N NH1 . ARG C 3 98  ? 92.788  85.836  -51.900 1.00 52.28  ? 98  ARG H2 NH1 1 
ATOM 5960 N NH2 . ARG C 3 98  ? 92.372  86.790  -53.933 1.00 53.18  ? 98  ARG H2 NH2 1 
ATOM 5961 N N   . GLY C 3 99  ? 96.298  89.685  -53.555 1.00 51.67  ? 99  GLY H2 N   1 
ATOM 5962 C CA  . GLY C 3 99  ? 95.663  90.948  -53.850 1.00 55.06  ? 99  GLY H2 CA  1 
ATOM 5963 C C   . GLY C 3 99  ? 94.163  90.850  -53.758 1.00 57.97  ? 99  GLY H2 C   1 
ATOM 5964 O O   . GLY C 3 99  ? 93.597  89.840  -53.346 1.00 57.98  ? 99  GLY H2 O   1 
ATOM 5965 N N   . SER C 3 100 ? 93.506  91.930  -54.158 1.00 60.79  ? 100 SER H2 N   1 
ATOM 5966 C CA  . SER C 3 100 ? 92.074  92.032  -53.932 1.00 62.77  ? 100 SER H2 CA  1 
ATOM 5967 C C   . SER C 3 100 ? 91.245  91.278  -54.957 1.00 63.89  ? 100 SER H2 C   1 
ATOM 5968 O O   . SER C 3 100 ? 90.045  91.102  -54.741 1.00 63.76  ? 100 SER H2 O   1 
ATOM 5969 C CB  . SER C 3 100 ? 91.639  93.497  -53.931 1.00 30.00  ? 100 SER H2 CB  1 
ATOM 5970 O OG  . SER C 3 100 ? 91.758  94.067  -55.222 1.00 30.00  ? 100 SER H2 OG  1 
ATOM 5971 N N   . HIS C 3 101 ? 91.828  90.858  -56.076 1.00 64.77  ? 101 HIS H2 N   1 
ATOM 5972 C CA  . HIS C 3 101 ? 90.987  90.382  -57.164 1.00 65.11  ? 101 HIS H2 CA  1 
ATOM 5973 C C   . HIS C 3 101 ? 90.541  88.941  -56.993 1.00 64.22  ? 101 HIS H2 C   1 
ATOM 5974 O O   . HIS C 3 101 ? 89.355  88.677  -56.779 1.00 64.51  ? 101 HIS H2 O   1 
ATOM 5975 C CB  . HIS C 3 101 ? 91.696  90.522  -58.503 1.00 67.39  ? 101 HIS H2 CB  1 
ATOM 5976 C CG  . HIS C 3 101 ? 90.888  90.019  -59.653 1.00 69.35  ? 101 HIS H2 CG  1 
ATOM 5977 N ND1 . HIS C 3 101 ? 89.578  90.387  -59.854 1.00 70.10  ? 101 HIS H2 ND1 1 
ATOM 5978 C CD2 . HIS C 3 101 ? 91.196  89.164  -60.654 1.00 69.59  ? 101 HIS H2 CD2 1 
ATOM 5979 C CE1 . HIS C 3 101 ? 89.115  89.786  -60.935 1.00 69.97  ? 101 HIS H2 CE1 1 
ATOM 5980 N NE2 . HIS C 3 101 ? 90.077  89.035  -61.437 1.00 70.27  ? 101 HIS H2 NE2 1 
ATOM 5981 N N   . GLY C 3 102 ? 91.470  88.002  -57.067 1.00 62.53  ? 102 GLY H2 N   1 
ATOM 5982 C CA  . GLY C 3 102 ? 91.077  86.612  -57.071 1.00 60.53  ? 102 GLY H2 CA  1 
ATOM 5983 C C   . GLY C 3 102 ? 91.887  85.766  -58.020 1.00 58.84  ? 102 GLY H2 C   1 
ATOM 5984 O O   . GLY C 3 102 ? 91.898  84.542  -57.898 1.00 58.26  ? 102 GLY H2 O   1 
ATOM 5985 N N   . SER C 3 103 ? 92.568  86.393  -58.969 1.00 56.84  ? 103 SER H2 N   1 
ATOM 5986 C CA  . SER C 3 103 ? 93.459  85.692  -59.875 1.00 54.36  ? 103 SER H2 CA  1 
ATOM 5987 C C   . SER C 3 103 ? 94.840  85.677  -59.257 1.00 52.34  ? 103 SER H2 C   1 
ATOM 5988 O O   . SER C 3 103 ? 95.168  86.528  -58.434 1.00 52.07  ? 103 SER H2 O   1 
ATOM 5989 C CB  . SER C 3 103 ? 93.529  86.376  -61.224 1.00 54.32  ? 103 SER H2 CB  1 
ATOM 5990 O OG  . SER C 3 103 ? 93.841  87.734  -61.044 1.00 55.08  ? 103 SER H2 OG  1 
ATOM 5991 N N   . TYR C 3 104 ? 95.665  84.716  -59.661 1.00 50.17  ? 104 TYR H2 N   1 
ATOM 5992 C CA  . TYR C 3 104 ? 96.985  84.568  -59.054 1.00 49.08  ? 104 TYR H2 CA  1 
ATOM 5993 C C   . TYR C 3 104 ? 97.975  85.520  -59.717 1.00 45.90  ? 104 TYR H2 C   1 
ATOM 5994 O O   . TYR C 3 104 ? 98.915  85.133  -60.410 1.00 46.21  ? 104 TYR H2 O   1 
ATOM 5995 C CB  . TYR C 3 104 ? 97.448  83.127  -59.110 1.00 51.57  ? 104 TYR H2 CB  1 
ATOM 5996 C CG  . TYR C 3 104 ? 97.267  82.462  -57.781 1.00 53.89  ? 104 TYR H2 CG  1 
ATOM 5997 C CD1 . TYR C 3 104 ? 98.194  82.645  -56.775 1.00 55.20  ? 104 TYR H2 CD1 1 
ATOM 5998 C CD2 . TYR C 3 104 ? 96.154  81.686  -57.516 1.00 54.25  ? 104 TYR H2 CD2 1 
ATOM 5999 C CE1 . TYR C 3 104 ? 98.031  82.063  -55.555 1.00 55.62  ? 104 TYR H2 CE1 1 
ATOM 6000 C CE2 . TYR C 3 104 ? 95.988  81.091  -56.298 1.00 54.97  ? 104 TYR H2 CE2 1 
ATOM 6001 C CZ  . TYR C 3 104 ? 96.929  81.289  -55.320 1.00 56.29  ? 104 TYR H2 CZ  1 
ATOM 6002 O OH  . TYR C 3 104 ? 96.762  80.703  -54.096 1.00 56.36  ? 104 TYR H2 OH  1 
ATOM 6003 N N   . SER C 3 105 ? 97.750  86.796  -59.461 1.00 41.67  ? 105 SER H2 N   1 
ATOM 6004 C CA  . SER C 3 105 ? 98.566  87.891  -59.958 1.00 37.96  ? 105 SER H2 CA  1 
ATOM 6005 C C   . SER C 3 105 ? 98.961  88.679  -58.723 1.00 35.07  ? 105 SER H2 C   1 
ATOM 6006 O O   . SER C 3 105 ? 98.118  89.348  -58.126 1.00 32.00  ? 105 SER H2 O   1 
ATOM 6007 C CB  . SER C 3 105 ? 97.787  88.743  -60.936 1.00 38.47  ? 105 SER H2 CB  1 
ATOM 6008 O OG  . SER C 3 105 ? 96.684  89.332  -60.285 1.00 42.35  ? 105 SER H2 OG  1 
ATOM 6009 N N   . PHE C 3 106 ? 100.233 88.603  -58.348 1.00 32.11  ? 106 PHE H2 N   1 
ATOM 6010 C CA  . PHE C 3 106 ? 100.697 89.071  -57.049 1.00 29.34  ? 106 PHE H2 CA  1 
ATOM 6011 C C   . PHE C 3 106 ? 100.744 90.588  -57.003 1.00 28.41  ? 106 PHE H2 C   1 
ATOM 6012 O O   . PHE C 3 106 ? 101.499 91.216  -57.745 1.00 26.08  ? 106 PHE H2 O   1 
ATOM 6013 C CB  . PHE C 3 106 ? 102.069 88.482  -56.769 1.00 31.60  ? 106 PHE H2 CB  1 
ATOM 6014 C CG  . PHE C 3 106 ? 102.186 87.048  -57.148 1.00 31.32  ? 106 PHE H2 CG  1 
ATOM 6015 C CD1 . PHE C 3 106 ? 101.575 86.076  -56.392 1.00 33.64  ? 106 PHE H2 CD1 1 
ATOM 6016 C CD2 . PHE C 3 106 ? 102.892 86.670  -58.264 1.00 33.76  ? 106 PHE H2 CD2 1 
ATOM 6017 C CE1 . PHE C 3 106 ? 101.674 84.757  -56.738 1.00 33.74  ? 106 PHE H2 CE1 1 
ATOM 6018 C CE2 . PHE C 3 106 ? 102.991 85.350  -58.613 1.00 33.69  ? 106 PHE H2 CE2 1 
ATOM 6019 C CZ  . PHE C 3 106 ? 102.383 84.395  -57.847 1.00 34.57  ? 106 PHE H2 CZ  1 
ATOM 6020 N N   . ALA C 3 107 ? 99.964  91.182  -56.110 1.00 27.23  ? 107 ALA H2 N   1 
ATOM 6021 C CA  . ALA C 3 107 ? 99.880  92.630  -56.014 1.00 27.17  ? 107 ALA H2 CA  1 
ATOM 6022 C C   . ALA C 3 107 ? 100.868 93.207  -55.009 1.00 27.51  ? 107 ALA H2 C   1 
ATOM 6023 O O   . ALA C 3 107 ? 101.435 94.276  -55.247 1.00 28.76  ? 107 ALA H2 O   1 
ATOM 6024 C CB  . ALA C 3 107 ? 98.458  93.048  -55.655 1.00 27.26  ? 107 ALA H2 CB  1 
ATOM 6025 N N   . TYR C 3 108 ? 101.079 92.538  -53.883 1.00 28.00  ? 108 TYR H2 N   1 
ATOM 6026 C CA  . TYR C 3 108 ? 101.983 93.031  -52.853 1.00 28.91  ? 108 TYR H2 CA  1 
ATOM 6027 C C   . TYR C 3 108 ? 103.147 92.068  -52.698 1.00 29.12  ? 108 TYR H2 C   1 
ATOM 6028 O O   . TYR C 3 108 ? 102.956 90.918  -52.297 1.00 29.89  ? 108 TYR H2 O   1 
ATOM 6029 C CB  . TYR C 3 108 ? 101.248 93.215  -51.529 1.00 29.79  ? 108 TYR H2 CB  1 
ATOM 6030 C CG  . TYR C 3 108 ? 99.999  94.028  -51.688 1.00 32.10  ? 108 TYR H2 CG  1 
ATOM 6031 C CD1 . TYR C 3 108 ? 100.059 95.393  -51.910 1.00 32.98  ? 108 TYR H2 CD1 1 
ATOM 6032 C CD2 . TYR C 3 108 ? 98.764  93.430  -51.655 1.00 33.25  ? 108 TYR H2 CD2 1 
ATOM 6033 C CE1 . TYR C 3 108 ? 98.905  96.136  -52.077 1.00 35.73  ? 108 TYR H2 CE1 1 
ATOM 6034 C CE2 . TYR C 3 108 ? 97.610  94.159  -51.814 1.00 35.50  ? 108 TYR H2 CE2 1 
ATOM 6035 C CZ  . TYR C 3 108 ? 97.685  95.505  -52.023 1.00 36.61  ? 108 TYR H2 CZ  1 
ATOM 6036 O OH  . TYR C 3 108 ? 96.531  96.222  -52.178 1.00 40.40  ? 108 TYR H2 OH  1 
ATOM 6037 N N   . TRP C 3 109 ? 104.349 92.538  -53.014 1.00 28.52  ? 109 TRP H2 N   1 
ATOM 6038 C CA  . TRP C 3 109 ? 105.554 91.739  -52.896 1.00 27.10  ? 109 TRP H2 CA  1 
ATOM 6039 C C   . TRP C 3 109 ? 106.324 92.159  -51.654 1.00 27.49  ? 109 TRP H2 C   1 
ATOM 6040 O O   . TRP C 3 109 ? 106.036 93.183  -51.033 1.00 25.86  ? 109 TRP H2 O   1 
ATOM 6041 C CB  . TRP C 3 109 ? 106.468 91.883  -54.117 1.00 26.02  ? 109 TRP H2 CB  1 
ATOM 6042 C CG  . TRP C 3 109 ? 105.886 91.481  -55.427 1.00 23.64  ? 109 TRP H2 CG  1 
ATOM 6043 C CD1 . TRP C 3 109 ? 104.893 92.105  -56.104 1.00 23.11  ? 109 TRP H2 CD1 1 
ATOM 6044 C CD2 . TRP C 3 109 ? 106.296 90.382  -56.243 1.00 24.98  ? 109 TRP H2 CD2 1 
ATOM 6045 N NE1 . TRP C 3 109 ? 104.641 91.459  -57.281 1.00 24.89  ? 109 TRP H2 NE1 1 
ATOM 6046 C CE2 . TRP C 3 109 ? 105.495 90.396  -57.391 1.00 24.06  ? 109 TRP H2 CE2 1 
ATOM 6047 C CE3 . TRP C 3 109 ? 107.258 89.382  -56.107 1.00 25.98  ? 109 TRP H2 CE3 1 
ATOM 6048 C CZ2 . TRP C 3 109 ? 105.620 89.450  -58.393 1.00 26.15  ? 109 TRP H2 CZ2 1 
ATOM 6049 C CZ3 . TRP C 3 109 ? 107.384 88.447  -57.109 1.00 25.81  ? 109 TRP H2 CZ3 1 
ATOM 6050 C CH2 . TRP C 3 109 ? 106.574 88.490  -58.238 1.00 26.30  ? 109 TRP H2 CH2 1 
ATOM 6051 N N   . GLY C 3 110 ? 107.318 91.355  -51.303 1.00 27.04  ? 110 GLY H2 N   1 
ATOM 6052 C CA  . GLY C 3 110 ? 108.270 91.740  -50.292 1.00 28.29  ? 110 GLY H2 CA  1 
ATOM 6053 C C   . GLY C 3 110 ? 109.327 92.643  -50.878 1.00 28.15  ? 110 GLY H2 C   1 
ATOM 6054 O O   . GLY C 3 110 ? 109.281 93.033  -52.043 1.00 28.24  ? 110 GLY H2 O   1 
ATOM 6055 N N   . GLN C 3 111 ? 110.304 92.991  -50.051 1.00 29.35  ? 111 GLN H2 N   1 
ATOM 6056 C CA  . GLN C 3 111 ? 111.399 93.817  -50.532 1.00 27.94  ? 111 GLN H2 CA  1 
ATOM 6057 C C   . GLN C 3 111 ? 112.501 93.010  -51.192 1.00 27.82  ? 111 GLN H2 C   1 
ATOM 6058 O O   . GLN C 3 111 ? 113.468 93.598  -51.681 1.00 26.56  ? 111 GLN H2 O   1 
ATOM 6059 C CB  . GLN C 3 111 ? 111.996 94.633  -49.389 1.00 30.70  ? 111 GLN H2 CB  1 
ATOM 6060 C CG  . GLN C 3 111 ? 112.819 93.820  -48.427 1.00 32.82  ? 111 GLN H2 CG  1 
ATOM 6061 C CD  . GLN C 3 111 ? 112.069 93.541  -47.158 1.00 35.63  ? 111 GLN H2 CD  1 
ATOM 6062 O OE1 . GLN C 3 111 ? 110.838 93.558  -47.139 1.00 36.77  ? 111 GLN H2 OE1 1 
ATOM 6063 N NE2 . GLN C 3 111 ? 112.799 93.287  -46.080 1.00 36.66  ? 111 GLN H2 NE2 1 
ATOM 6064 N N   . GLY C 3 112 ? 112.381 91.688  -51.218 1.00 27.30  ? 112 GLY H2 N   1 
ATOM 6065 C CA  . GLY C 3 112 ? 113.425 90.845  -51.754 1.00 26.66  ? 112 GLY H2 CA  1 
ATOM 6066 C C   . GLY C 3 112 ? 114.479 90.543  -50.715 1.00 29.40  ? 112 GLY H2 C   1 
ATOM 6067 O O   . GLY C 3 112 ? 114.861 91.422  -49.943 1.00 28.42  ? 112 GLY H2 O   1 
ATOM 6068 N N   . THR C 3 113 ? 114.943 89.303  -50.666 1.00 29.15  ? 113 THR H2 N   1 
ATOM 6069 C CA  . THR C 3 113 ? 116.014 88.905  -49.764 1.00 29.58  ? 113 THR H2 CA  1 
ATOM 6070 C C   . THR C 3 113 ? 117.054 88.138  -50.559 1.00 30.94  ? 113 THR H2 C   1 
ATOM 6071 O O   . THR C 3 113 ? 116.810 87.004  -50.979 1.00 30.39  ? 113 THR H2 O   1 
ATOM 6072 C CB  . THR C 3 113 ? 115.485 88.062  -48.607 1.00 30.64  ? 113 THR H2 CB  1 
ATOM 6073 O OG1 . THR C 3 113 ? 114.615 88.864  -47.801 1.00 31.58  ? 113 THR H2 OG1 1 
ATOM 6074 C CG2 . THR C 3 113 ? 116.620 87.568  -47.754 1.00 28.83  ? 113 THR H2 CG2 1 
ATOM 6075 N N   . LEU C 3 114 ? 118.204 88.762  -50.769 1.00 30.68  ? 114 LEU H2 N   1 
ATOM 6076 C CA  . LEU C 3 114 ? 119.242 88.192  -51.613 1.00 33.52  ? 114 LEU H2 CA  1 
ATOM 6077 C C   . LEU C 3 114 ? 119.984 87.112  -50.843 1.00 34.89  ? 114 LEU H2 C   1 
ATOM 6078 O O   . LEU C 3 114 ? 120.528 87.368  -49.767 1.00 34.33  ? 114 LEU H2 O   1 
ATOM 6079 C CB  . LEU C 3 114 ? 120.198 89.287  -52.077 1.00 33.52  ? 114 LEU H2 CB  1 
ATOM 6080 C CG  . LEU C 3 114 ? 121.455 88.934  -52.875 1.00 34.25  ? 114 LEU H2 CG  1 
ATOM 6081 C CD1 . LEU C 3 114 ? 121.177 87.978  -54.021 1.00 34.06  ? 114 LEU H2 CD1 1 
ATOM 6082 C CD2 . LEU C 3 114 ? 122.103 90.195  -53.396 1.00 35.14  ? 114 LEU H2 CD2 1 
ATOM 6083 N N   . VAL C 3 115 ? 119.999 85.907  -51.396 1.00 37.34  ? 115 VAL H2 N   1 
ATOM 6084 C CA  . VAL C 3 115 ? 120.830 84.813  -50.918 1.00 38.57  ? 115 VAL H2 CA  1 
ATOM 6085 C C   . VAL C 3 115 ? 122.070 84.789  -51.792 1.00 39.70  ? 115 VAL H2 C   1 
ATOM 6086 O O   . VAL C 3 115 ? 121.969 84.909  -53.017 1.00 41.57  ? 115 VAL H2 O   1 
ATOM 6087 C CB  . VAL C 3 115 ? 120.085 83.473  -50.973 1.00 38.28  ? 115 VAL H2 CB  1 
ATOM 6088 C CG1 . VAL C 3 115 ? 120.869 82.393  -50.260 1.00 37.51  ? 115 VAL H2 CG1 1 
ATOM 6089 C CG2 . VAL C 3 115 ? 118.726 83.621  -50.352 1.00 37.69  ? 115 VAL H2 CG2 1 
ATOM 6090 N N   . THR C 3 116 ? 123.240 84.692  -51.167 1.00 40.60  ? 116 THR H2 N   1 
ATOM 6091 C CA  . THR C 3 116 ? 124.511 84.621  -51.880 1.00 42.52  ? 116 THR H2 CA  1 
ATOM 6092 C C   . THR C 3 116 ? 125.251 83.368  -51.438 1.00 43.61  ? 116 THR H2 C   1 
ATOM 6093 O O   . THR C 3 116 ? 126.022 83.415  -50.477 1.00 43.58  ? 116 THR H2 O   1 
ATOM 6094 C CB  . THR C 3 116 ? 125.384 85.853  -51.612 1.00 42.71  ? 116 THR H2 CB  1 
ATOM 6095 O OG1 . THR C 3 116 ? 125.982 85.738  -50.317 1.00 43.41  ? 116 THR H2 OG1 1 
ATOM 6096 C CG2 . THR C 3 116 ? 124.593 87.153  -51.679 1.00 43.15  ? 116 THR H2 CG2 1 
ATOM 6097 N N   . VAL C 3 117 ? 125.044 82.258  -52.140 1.00 45.41  ? 117 VAL H2 N   1 
ATOM 6098 C CA  . VAL C 3 117 ? 125.752 81.021  -51.831 1.00 45.55  ? 117 VAL H2 CA  1 
ATOM 6099 C C   . VAL C 3 117 ? 127.018 80.992  -52.681 1.00 45.49  ? 117 VAL H2 C   1 
ATOM 6100 O O   . VAL C 3 117 ? 127.009 81.432  -53.839 1.00 46.30  ? 117 VAL H2 O   1 
ATOM 6101 C CB  . VAL C 3 117 ? 124.869 79.769  -52.025 1.00 45.72  ? 117 VAL H2 CB  1 
ATOM 6102 C CG1 . VAL C 3 117 ? 124.585 79.429  -53.484 1.00 44.99  ? 117 VAL H2 CG1 1 
ATOM 6103 C CG2 . VAL C 3 117 ? 125.495 78.582  -51.340 1.00 44.56  ? 117 VAL H2 CG2 1 
ATOM 6104 N N   . SER C 3 118 ? 128.121 80.558  -52.073 1.00 45.13  ? 118 SER H2 N   1 
ATOM 6105 C CA  . SER C 3 118 ? 129.437 80.544  -52.707 1.00 43.97  ? 118 SER H2 CA  1 
ATOM 6106 C C   . SER C 3 118 ? 130.351 79.651  -51.876 1.00 43.12  ? 118 SER H2 C   1 
ATOM 6107 O O   . SER C 3 118 ? 129.921 79.017  -50.907 1.00 42.28  ? 118 SER H2 O   1 
ATOM 6108 C CB  . SER C 3 118 ? 130.024 81.952  -52.839 1.00 44.87  ? 118 SER H2 CB  1 
ATOM 6109 O OG  . SER C 3 118 ? 129.813 82.702  -51.659 1.00 45.52  ? 118 SER H2 OG  1 
ATOM 6110 N N   . GLY C 3 119 ? 131.620 79.612  -52.265 1.00 42.21  ? 119 GLY H2 N   1 
ATOM 6111 C CA  . GLY C 3 119 ? 132.633 78.884  -51.524 1.00 40.88  ? 119 GLY H2 CA  1 
ATOM 6112 C C   . GLY C 3 119 ? 133.519 79.788  -50.685 1.00 39.51  ? 119 GLY H2 C   1 
ATOM 6113 O O   . GLY C 3 119 ? 133.925 80.866  -51.121 1.00 40.33  ? 119 GLY H2 O   1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A1 . n 
A 1 2   SER 2   2   ?   ?   ?   A1 . n 
A 1 3   ASP 3   3   ?   ?   ?   A1 . n 
A 1 4   GLY 4   4   ?   ?   ?   A1 . n 
A 1 5   ALA 5   5   ?   ?   ?   A1 . n 
A 1 6   VAL 6   6   ?   ?   ?   A1 . n 
A 1 7   GLN 7   7   ?   ?   ?   A1 . n 
A 1 8   PRO 8   8   ?   ?   ?   A1 . n 
A 1 9   ASP 9   9   ?   ?   ?   A1 . n 
A 1 10  GLY 10  10  ?   ?   ?   A1 . n 
A 1 11  GLY 11  11  ?   ?   ?   A1 . n 
A 1 12  GLN 12  12  ?   ?   ?   A1 . n 
A 1 13  PRO 13  13  ?   ?   ?   A1 . n 
A 1 14  ALA 14  14  ?   ?   ?   A1 . n 
A 1 15  VAL 15  15  ?   ?   ?   A1 . n 
A 1 16  ARG 16  16  ?   ?   ?   A1 . n 
A 1 17  ASN 17  17  ?   ?   ?   A1 . n 
A 1 18  GLU 18  18  ?   ?   ?   A1 . n 
A 1 19  ARG 19  19  ?   ?   ?   A1 . n 
A 1 20  ALA 20  20  ?   ?   ?   A1 . n 
A 1 21  THR 21  21  ?   ?   ?   A1 . n 
A 1 22  GLY 22  22  ?   ?   ?   A1 . n 
A 1 23  SER 23  23  ?   ?   ?   A1 . n 
A 1 24  GLY 24  24  ?   ?   ?   A1 . n 
A 1 25  ASN 25  25  ?   ?   ?   A1 . n 
A 1 26  GLY 26  26  ?   ?   ?   A1 . n 
A 1 27  SER 27  27  ?   ?   ?   A1 . n 
A 1 28  GLY 28  28  ?   ?   ?   A1 . n 
A 1 29  GLY 29  29  ?   ?   ?   A1 . n 
A 1 30  GLY 30  30  ?   ?   ?   A1 . n 
A 1 31  GLY 31  31  ?   ?   ?   A1 . n 
A 1 32  GLY 32  32  ?   ?   ?   A1 . n 
A 1 33  GLY 33  33  ?   ?   ?   A1 . n 
A 1 34  GLY 34  34  ?   ?   ?   A1 . n 
A 1 35  SER 35  35  ?   ?   ?   A1 . n 
A 1 36  GLY 36  36  ?   ?   ?   A1 . n 
A 1 37  GLY 37  37  37  GLY GLY A1 . n 
A 1 38  VAL 38  38  38  VAL VAL A1 . n 
A 1 39  GLY 39  39  39  GLY GLY A1 . n 
A 1 40  ILE 40  40  40  ILE ILE A1 . n 
A 1 41  SER 41  41  41  SER SER A1 . n 
A 1 42  THR 42  42  42  THR THR A1 . n 
A 1 43  GLY 43  43  43  GLY GLY A1 . n 
A 1 44  THR 44  44  44  THR THR A1 . n 
A 1 45  PHE 45  45  45  PHE PHE A1 . n 
A 1 46  ASN 46  46  46  ASN ASN A1 . n 
A 1 47  ASN 47  47  47  ASN ASN A1 . n 
A 1 48  GLN 48  48  48  GLN GLN A1 . n 
A 1 49  THR 49  49  49  THR THR A1 . n 
A 1 50  GLU 50  50  50  GLU GLU A1 . n 
A 1 51  PHE 51  51  51  PHE PHE A1 . n 
A 1 52  LYS 52  52  52  LYS LYS A1 . n 
A 1 53  PHE 53  53  53  PHE PHE A1 . n 
A 1 54  LEU 54  54  54  LEU LEU A1 . n 
A 1 55  GLU 55  55  55  GLU GLU A1 . n 
A 1 56  ASN 56  56  56  ASN ASN A1 . n 
A 1 57  GLY 57  57  57  GLY GLY A1 . n 
A 1 58  TRP 58  58  58  TRP TRP A1 . n 
A 1 59  VAL 59  59  59  VAL VAL A1 . n 
A 1 60  GLU 60  60  60  GLU GLU A1 . n 
A 1 61  ILE 61  61  61  ILE ILE A1 . n 
A 1 62  THR 62  62  62  THR THR A1 . n 
A 1 63  ALA 63  63  63  ALA ALA A1 . n 
A 1 64  ASN 64  64  64  ASN ASN A1 . n 
A 1 65  SER 65  65  65  SER SER A1 . n 
A 1 66  SER 66  66  66  SER SER A1 . n 
A 1 67  ARG 67  67  67  ARG ARG A1 . n 
A 1 68  LEU 68  68  68  LEU LEU A1 . n 
A 1 69  VAL 69  69  69  VAL VAL A1 . n 
A 1 70  HIS 70  70  70  HIS HIS A1 . n 
A 1 71  LEU 71  71  71  LEU LEU A1 . n 
A 1 72  ASN 72  72  72  ASN ASN A1 . n 
A 1 73  MET 73  73  73  MET MET A1 . n 
A 1 74  PRO 74  74  74  PRO PRO A1 . n 
A 1 75  GLU 75  75  75  GLU GLU A1 . n 
A 1 76  SER 76  76  76  SER SER A1 . n 
A 1 77  GLU 77  77  77  GLU GLU A1 . n 
A 1 78  ASN 78  78  78  ASN ASN A1 . n 
A 1 79  TYR 79  79  79  TYR TYR A1 . n 
A 1 80  ARG 80  80  80  ARG ARG A1 . n 
A 1 81  ARG 81  81  81  ARG ARG A1 . n 
A 1 82  VAL 82  82  82  VAL VAL A1 . n 
A 1 83  VAL 83  83  83  VAL VAL A1 . n 
A 1 84  VAL 84  84  84  VAL VAL A1 . n 
A 1 85  ASN 85  85  85  ASN ASN A1 . n 
A 1 86  ASN 86  86  86  ASN ASN A1 . n 
A 1 87  MET 87  87  87  MET MET A1 . n 
A 1 88  ASP 88  88  88  ASP ASP A1 . n 
A 1 89  LYS 89  89  89  LYS LYS A1 . n 
A 1 90  THR 90  90  90  THR THR A1 . n 
A 1 91  ALA 91  91  91  ALA ALA A1 . n 
A 1 92  VAL 92  92  92  VAL VAL A1 . n 
A 1 93  ASN 93  93  93  ASN ASN A1 . n 
A 1 94  GLY 94  94  94  GLY GLY A1 . n 
A 1 95  ASN 95  95  95  ASN ASN A1 . n 
A 1 96  MET 96  96  96  MET MET A1 . n 
A 1 97  ALA 97  97  97  ALA ALA A1 . n 
A 1 98  LEU 98  98  98  LEU LEU A1 . n 
A 1 99  ASP 99  99  99  ASP ASP A1 . n 
A 1 100 ASP 100 100 100 ASP ASP A1 . n 
A 1 101 ILE 101 101 101 ILE ILE A1 . n 
A 1 102 HIS 102 102 102 HIS HIS A1 . n 
A 1 103 ALA 103 103 103 ALA ALA A1 . n 
A 1 104 GLN 104 104 104 GLN GLN A1 . n 
A 1 105 ILE 105 105 105 ILE ILE A1 . n 
A 1 106 VAL 106 106 106 VAL VAL A1 . n 
A 1 107 THR 107 107 107 THR THR A1 . n 
A 1 108 PRO 108 108 108 PRO PRO A1 . n 
A 1 109 TRP 109 109 109 TRP TRP A1 . n 
A 1 110 SER 110 110 110 SER SER A1 . n 
A 1 111 LEU 111 111 111 LEU LEU A1 . n 
A 1 112 VAL 112 112 112 VAL VAL A1 . n 
A 1 113 ASP 113 113 113 ASP ASP A1 . n 
A 1 114 ALA 114 114 114 ALA ALA A1 . n 
A 1 115 ASN 115 115 115 ASN ASN A1 . n 
A 1 116 ALA 116 116 116 ALA ALA A1 . n 
A 1 117 TRP 117 117 117 TRP TRP A1 . n 
A 1 118 GLY 118 118 118 GLY GLY A1 . n 
A 1 119 VAL 119 119 119 VAL VAL A1 . n 
A 1 120 TRP 120 120 120 TRP TRP A1 . n 
A 1 121 PHE 121 121 121 PHE PHE A1 . n 
A 1 122 ASN 122 122 122 ASN ASN A1 . n 
A 1 123 PRO 123 123 123 PRO PRO A1 . n 
A 1 124 GLY 124 124 124 GLY GLY A1 . n 
A 1 125 ASP 125 125 125 ASP ASP A1 . n 
A 1 126 TRP 126 126 126 TRP TRP A1 . n 
A 1 127 GLN 127 127 127 GLN GLN A1 . n 
A 1 128 LEU 128 128 128 LEU LEU A1 . n 
A 1 129 ILE 129 129 129 ILE ILE A1 . n 
A 1 130 VAL 130 130 130 VAL VAL A1 . n 
A 1 131 ASN 131 131 131 ASN ASN A1 . n 
A 1 132 THR 132 132 132 THR THR A1 . n 
A 1 133 MET 133 133 133 MET MET A1 . n 
A 1 134 SER 134 134 134 SER SER A1 . n 
A 1 135 GLU 135 135 135 GLU GLU A1 . n 
A 1 136 LEU 136 136 136 LEU LEU A1 . n 
A 1 137 HIS 137 137 137 HIS HIS A1 . n 
A 1 138 LEU 138 138 138 LEU LEU A1 . n 
A 1 139 VAL 139 139 139 VAL VAL A1 . n 
A 1 140 SER 140 140 140 SER SER A1 . n 
A 1 141 PHE 141 141 141 PHE PHE A1 . n 
A 1 142 GLU 142 142 142 GLU GLU A1 . n 
A 1 143 GLN 143 143 143 GLN GLN A1 . n 
A 1 144 GLU 144 144 144 GLU GLU A1 . n 
A 1 145 ILE 145 145 145 ILE ILE A1 . n 
A 1 146 PHE 146 146 146 PHE PHE A1 . n 
A 1 147 ASN 147 147 147 ASN ASN A1 . n 
A 1 148 VAL 148 148 148 VAL VAL A1 . n 
A 1 149 VAL 149 149 149 VAL VAL A1 . n 
A 1 150 LEU 150 150 150 LEU LEU A1 . n 
A 1 151 LYS 151 151 151 LYS LYS A1 . n 
A 1 152 THR 152 152 152 THR THR A1 . n 
A 1 153 VAL 153 153 153 VAL VAL A1 . n 
A 1 154 SER 154 154 154 SER SER A1 . n 
A 1 155 GLU 155 155 155 GLU GLU A1 . n 
A 1 156 SER 156 156 156 SER SER A1 . n 
A 1 157 ALA 157 157 157 ALA ALA A1 . n 
A 1 158 THR 158 158 158 THR THR A1 . n 
A 1 159 GLN 159 159 159 GLN GLN A1 . n 
A 1 160 PRO 160 160 160 PRO PRO A1 . n 
A 1 161 PRO 161 161 161 PRO PRO A1 . n 
A 1 162 THR 162 162 162 THR THR A1 . n 
A 1 163 LYS 163 163 163 LYS LYS A1 . n 
A 1 164 VAL 164 164 164 VAL VAL A1 . n 
A 1 165 TYR 165 165 165 TYR TYR A1 . n 
A 1 166 ASN 166 166 166 ASN ASN A1 . n 
A 1 167 ASN 167 167 167 ASN ASN A1 . n 
A 1 168 ASP 168 168 168 ASP ASP A1 . n 
A 1 169 LEU 169 169 169 LEU LEU A1 . n 
A 1 170 THR 170 170 170 THR THR A1 . n 
A 1 171 ALA 171 171 171 ALA ALA A1 . n 
A 1 172 SER 172 172 172 SER SER A1 . n 
A 1 173 LEU 173 173 173 LEU LEU A1 . n 
A 1 174 MET 174 174 174 MET MET A1 . n 
A 1 175 VAL 175 175 175 VAL VAL A1 . n 
A 1 176 ALA 176 176 176 ALA ALA A1 . n 
A 1 177 LEU 177 177 177 LEU LEU A1 . n 
A 1 178 ASP 178 178 178 ASP ASP A1 . n 
A 1 179 SER 179 179 179 SER SER A1 . n 
A 1 180 ASN 180 180 180 ASN ASN A1 . n 
A 1 181 ASN 181 181 181 ASN ASN A1 . n 
A 1 182 THR 182 182 182 THR THR A1 . n 
A 1 183 MET 183 183 183 MET MET A1 . n 
A 1 184 PRO 184 184 184 PRO PRO A1 . n 
A 1 185 PHE 185 185 185 PHE PHE A1 . n 
A 1 186 THR 186 186 186 THR THR A1 . n 
A 1 187 PRO 187 187 187 PRO PRO A1 . n 
A 1 188 ALA 188 188 188 ALA ALA A1 . n 
A 1 189 ALA 189 189 189 ALA ALA A1 . n 
A 1 190 MET 190 190 190 MET MET A1 . n 
A 1 191 ARG 191 191 191 ARG ARG A1 . n 
A 1 192 SER 192 192 192 SER SER A1 . n 
A 1 193 GLU 193 193 193 GLU GLU A1 . n 
A 1 194 THR 194 194 194 THR THR A1 . n 
A 1 195 LEU 195 195 195 LEU LEU A1 . n 
A 1 196 GLY 196 196 196 GLY GLY A1 . n 
A 1 197 PHE 197 197 197 PHE PHE A1 . n 
A 1 198 TYR 198 198 198 TYR TYR A1 . n 
A 1 199 PRO 199 199 199 PRO PRO A1 . n 
A 1 200 TRP 200 200 200 TRP TRP A1 . n 
A 1 201 LYS 201 201 201 LYS LYS A1 . n 
A 1 202 PRO 202 202 202 PRO PRO A1 . n 
A 1 203 THR 203 203 203 THR THR A1 . n 
A 1 204 ILE 204 204 204 ILE ILE A1 . n 
A 1 205 PRO 205 205 205 PRO PRO A1 . n 
A 1 206 THR 206 206 206 THR THR A1 . n 
A 1 207 PRO 207 207 207 PRO PRO A1 . n 
A 1 208 TRP 208 208 208 TRP TRP A1 . n 
A 1 209 ARG 209 209 209 ARG ARG A1 . n 
A 1 210 TYR 210 210 210 TYR TYR A1 . n 
A 1 211 TYR 211 211 211 TYR TYR A1 . n 
A 1 212 PHE 212 212 212 PHE PHE A1 . n 
A 1 213 GLN 213 213 213 GLN GLN A1 . n 
A 1 214 TRP 214 214 214 TRP TRP A1 . n 
A 1 215 ASP 215 215 215 ASP ASP A1 . n 
A 1 216 ARG 216 216 216 ARG ARG A1 . n 
A 1 217 THR 217 217 217 THR THR A1 . n 
A 1 218 LEU 218 218 218 LEU LEU A1 . n 
A 1 219 ILE 219 219 219 ILE ILE A1 . n 
A 1 220 PRO 220 220 220 PRO PRO A1 . n 
A 1 221 SER 221 221 221 SER SER A1 . n 
A 1 222 HIS 222 222 222 HIS HIS A1 . n 
A 1 223 THR 223 223 223 THR THR A1 . n 
A 1 224 GLY 224 224 224 GLY GLY A1 . n 
A 1 225 THR 225 225 225 THR THR A1 . n 
A 1 226 SER 226 226 226 SER SER A1 . n 
A 1 227 GLY 227 227 227 GLY GLY A1 . n 
A 1 228 THR 228 228 228 THR THR A1 . n 
A 1 229 PRO 229 229 229 PRO PRO A1 . n 
A 1 230 THR 230 230 230 THR THR A1 . n 
A 1 231 ASN 231 231 231 ASN ASN A1 . n 
A 1 232 ILE 232 232 232 ILE ILE A1 . n 
A 1 233 TYR 233 233 233 TYR TYR A1 . n 
A 1 234 HIS 234 234 234 HIS HIS A1 . n 
A 1 235 GLY 235 235 235 GLY GLY A1 . n 
A 1 236 THR 236 236 236 THR THR A1 . n 
A 1 237 ASP 237 237 237 ASP ASP A1 . n 
A 1 238 PRO 238 238 238 PRO PRO A1 . n 
A 1 239 ASP 239 239 239 ASP ASP A1 . n 
A 1 240 ASP 240 240 240 ASP ASP A1 . n 
A 1 241 VAL 241 241 241 VAL VAL A1 . n 
A 1 242 GLN 242 242 242 GLN GLN A1 . n 
A 1 243 PHE 243 243 243 PHE PHE A1 . n 
A 1 244 TYR 244 244 244 TYR TYR A1 . n 
A 1 245 THR 245 245 245 THR THR A1 . n 
A 1 246 ILE 246 246 246 ILE ILE A1 . n 
A 1 247 GLU 247 247 247 GLU GLU A1 . n 
A 1 248 ASN 248 248 248 ASN ASN A1 . n 
A 1 249 SER 249 249 249 SER SER A1 . n 
A 1 250 VAL 250 250 250 VAL VAL A1 . n 
A 1 251 PRO 251 251 251 PRO PRO A1 . n 
A 1 252 VAL 252 252 252 VAL VAL A1 . n 
A 1 253 HIS 253 253 253 HIS HIS A1 . n 
A 1 254 LEU 254 254 254 LEU LEU A1 . n 
A 1 255 LEU 255 255 255 LEU LEU A1 . n 
A 1 256 ARG 256 256 256 ARG ARG A1 . n 
A 1 257 THR 257 257 257 THR THR A1 . n 
A 1 258 GLY 258 258 258 GLY GLY A1 . n 
A 1 259 ASP 259 259 259 ASP ASP A1 . n 
A 1 260 GLU 260 260 260 GLU GLU A1 . n 
A 1 261 PHE 261 261 261 PHE PHE A1 . n 
A 1 262 ALA 262 262 262 ALA ALA A1 . n 
A 1 263 THR 263 263 263 THR THR A1 . n 
A 1 264 GLY 264 264 264 GLY GLY A1 . n 
A 1 265 THR 265 265 265 THR THR A1 . n 
A 1 266 PHE 266 266 266 PHE PHE A1 . n 
A 1 267 PHE 267 267 267 PHE PHE A1 . n 
A 1 268 PHE 268 268 268 PHE PHE A1 . n 
A 1 269 ASP 269 269 269 ASP ASP A1 . n 
A 1 270 CYS 270 270 270 CYS CYS A1 . n 
A 1 271 LYS 271 271 271 LYS LYS A1 . n 
A 1 272 PRO 272 272 272 PRO PRO A1 . n 
A 1 273 CYS 273 273 273 CYS CYS A1 . n 
A 1 274 ARG 274 274 274 ARG ARG A1 . n 
A 1 275 LEU 275 275 275 LEU LEU A1 . n 
A 1 276 THR 276 276 276 THR THR A1 . n 
A 1 277 HIS 277 277 277 HIS HIS A1 . n 
A 1 278 THR 278 278 278 THR THR A1 . n 
A 1 279 TRP 279 279 279 TRP TRP A1 . n 
A 1 280 GLN 280 280 280 GLN GLN A1 . n 
A 1 281 THR 281 281 281 THR THR A1 . n 
A 1 282 ASN 282 282 282 ASN ASN A1 . n 
A 1 283 ARG 283 283 283 ARG ARG A1 . n 
A 1 284 ALA 284 284 284 ALA ALA A1 . n 
A 1 285 LEU 285 285 285 LEU LEU A1 . n 
A 1 286 GLY 286 286 286 GLY GLY A1 . n 
A 1 287 LEU 287 287 287 LEU LEU A1 . n 
A 1 288 PRO 288 288 288 PRO PRO A1 . n 
A 1 289 PRO 289 289 289 PRO PRO A1 . n 
A 1 290 PHE 290 290 290 PHE PHE A1 . n 
A 1 291 LEU 291 291 291 LEU LEU A1 . n 
A 1 292 ASN 292 292 292 ASN ASN A1 . n 
A 1 293 SER 293 293 293 SER SER A1 . n 
A 1 294 LEU 294 294 294 LEU LEU A1 . n 
A 1 295 PRO 295 295 295 PRO PRO A1 . n 
A 1 296 GLN 296 296 296 GLN GLN A1 . n 
A 1 297 SER 297 297 297 SER SER A1 . n 
A 1 298 GLU 298 298 298 GLU GLU A1 . n 
A 1 299 GLY 299 299 299 GLY GLY A1 . n 
A 1 300 ALA 300 300 300 ALA ALA A1 . n 
A 1 301 THR 301 301 301 THR THR A1 . n 
A 1 302 ASN 302 302 302 ASN ASN A1 . n 
A 1 303 PHE 303 303 303 PHE PHE A1 . n 
A 1 304 GLY 304 304 304 GLY GLY A1 . n 
A 1 305 ASP 305 305 305 ASP ASP A1 . n 
A 1 306 ILE 306 306 306 ILE ILE A1 . n 
A 1 307 GLY 307 307 307 GLY GLY A1 . n 
A 1 308 VAL 308 308 308 VAL VAL A1 . n 
A 1 309 GLN 309 309 309 GLN GLN A1 . n 
A 1 310 GLN 310 310 310 GLN GLN A1 . n 
A 1 311 ASP 311 311 311 ASP ASP A1 . n 
A 1 312 LYS 312 312 312 LYS LYS A1 . n 
A 1 313 ARG 313 313 313 ARG ARG A1 . n 
A 1 314 ARG 314 314 314 ARG ARG A1 . n 
A 1 315 GLY 315 315 315 GLY GLY A1 . n 
A 1 316 VAL 316 316 316 VAL VAL A1 . n 
A 1 317 THR 317 317 317 THR THR A1 . n 
A 1 318 GLN 318 318 318 GLN GLN A1 . n 
A 1 319 MET 319 319 319 MET MET A1 . n 
A 1 320 GLY 320 320 320 GLY GLY A1 . n 
A 1 321 ASN 321 321 321 ASN ASN A1 . n 
A 1 322 THR 322 322 322 THR THR A1 . n 
A 1 323 ASN 323 323 323 ASN ASN A1 . n 
A 1 324 TYR 324 324 324 TYR TYR A1 . n 
A 1 325 ILE 325 325 325 ILE ILE A1 . n 
A 1 326 THR 326 326 326 THR THR A1 . n 
A 1 327 GLU 327 327 327 GLU GLU A1 . n 
A 1 328 ALA 328 328 328 ALA ALA A1 . n 
A 1 329 THR 329 329 329 THR THR A1 . n 
A 1 330 ILE 330 330 330 ILE ILE A1 . n 
A 1 331 MET 331 331 331 MET MET A1 . n 
A 1 332 ARG 332 332 332 ARG ARG A1 . n 
A 1 333 PRO 333 333 333 PRO PRO A1 . n 
A 1 334 ALA 334 334 334 ALA ALA A1 . n 
A 1 335 GLU 335 335 335 GLU GLU A1 . n 
A 1 336 VAL 336 336 336 VAL VAL A1 . n 
A 1 337 GLY 337 337 337 GLY GLY A1 . n 
A 1 338 TYR 338 338 338 TYR TYR A1 . n 
A 1 339 SER 339 339 339 SER SER A1 . n 
A 1 340 ALA 340 340 340 ALA ALA A1 . n 
A 1 341 PRO 341 341 341 PRO PRO A1 . n 
A 1 342 TYR 342 342 342 TYR TYR A1 . n 
A 1 343 TYR 343 343 343 TYR TYR A1 . n 
A 1 344 SER 344 344 344 SER SER A1 . n 
A 1 345 PHE 345 345 345 PHE PHE A1 . n 
A 1 346 GLU 346 346 346 GLU GLU A1 . n 
A 1 347 ALA 347 347 347 ALA ALA A1 . n 
A 1 348 SER 348 348 348 SER SER A1 . n 
A 1 349 THR 349 349 349 THR THR A1 . n 
A 1 350 GLN 350 350 350 GLN GLN A1 . n 
A 1 351 GLY 351 351 351 GLY GLY A1 . n 
A 1 352 PRO 352 352 352 PRO PRO A1 . n 
A 1 353 PHE 353 353 353 PHE PHE A1 . n 
A 1 354 LYS 354 354 354 LYS LYS A1 . n 
A 1 355 THR 355 355 355 THR THR A1 . n 
A 1 356 PRO 356 356 356 PRO PRO A1 . n 
A 1 357 ILE 357 357 357 ILE ILE A1 . n 
A 1 358 ALA 358 358 358 ALA ALA A1 . n 
A 1 359 ALA 359 359 359 ALA ALA A1 . n 
A 1 360 GLY 360 360 360 GLY GLY A1 . n 
A 1 361 ARG 361 361 361 ARG ARG A1 . n 
A 1 362 GLY 362 362 362 GLY GLY A1 . n 
A 1 363 GLY 363 363 363 GLY GLY A1 . n 
A 1 364 ALA 364 364 364 ALA ALA A1 . n 
A 1 365 GLN 365 365 365 GLN GLN A1 . n 
A 1 366 THR 366 366 366 THR THR A1 . n 
A 1 367 ASP 367 367 367 ASP ASP A1 . n 
A 1 368 GLU 368 368 368 GLU GLU A1 . n 
A 1 369 ASN 369 369 369 ASN ASN A1 . n 
A 1 370 GLN 370 370 370 GLN GLN A1 . n 
A 1 371 ALA 371 371 371 ALA ALA A1 . n 
A 1 372 ALA 372 372 372 ALA ALA A1 . n 
A 1 373 ASP 373 373 373 ASP ASP A1 . n 
A 1 374 GLY 374 374 374 GLY GLY A1 . n 
A 1 375 ASN 375 375 375 ASN ASN A1 . n 
A 1 376 PRO 376 376 376 PRO PRO A1 . n 
A 1 377 ARG 377 377 377 ARG ARG A1 . n 
A 1 378 TYR 378 378 378 TYR TYR A1 . n 
A 1 379 ALA 379 379 379 ALA ALA A1 . n 
A 1 380 PHE 380 380 380 PHE PHE A1 . n 
A 1 381 GLY 381 381 381 GLY GLY A1 . n 
A 1 382 ARG 382 382 382 ARG ARG A1 . n 
A 1 383 GLN 383 383 383 GLN GLN A1 . n 
A 1 384 HIS 384 384 384 HIS HIS A1 . n 
A 1 385 GLY 385 385 385 GLY GLY A1 . n 
A 1 386 GLN 386 386 386 GLN GLN A1 . n 
A 1 387 LYS 387 387 387 LYS LYS A1 . n 
A 1 388 THR 388 388 388 THR THR A1 . n 
A 1 389 THR 389 389 389 THR THR A1 . n 
A 1 390 THR 390 390 390 THR THR A1 . n 
A 1 391 THR 391 391 391 THR THR A1 . n 
A 1 392 GLY 392 392 392 GLY GLY A1 . n 
A 1 393 GLU 393 393 393 GLU GLU A1 . n 
A 1 394 THR 394 394 394 THR THR A1 . n 
A 1 395 PRO 395 395 395 PRO PRO A1 . n 
A 1 396 GLU 396 396 396 GLU GLU A1 . n 
A 1 397 ARG 397 397 397 ARG ARG A1 . n 
A 1 398 PHE 398 398 398 PHE PHE A1 . n 
A 1 399 THR 399 399 399 THR THR A1 . n 
A 1 400 TYR 400 400 400 TYR TYR A1 . n 
A 1 401 ILE 401 401 401 ILE ILE A1 . n 
A 1 402 ALA 402 402 402 ALA ALA A1 . n 
A 1 403 HIS 403 403 403 HIS HIS A1 . n 
A 1 404 GLN 404 404 404 GLN GLN A1 . n 
A 1 405 ASP 405 405 405 ASP ASP A1 . n 
A 1 406 THR 406 406 406 THR THR A1 . n 
A 1 407 GLY 407 407 407 GLY GLY A1 . n 
A 1 408 ARG 408 408 408 ARG ARG A1 . n 
A 1 409 TYR 409 409 409 TYR TYR A1 . n 
A 1 410 PRO 410 410 410 PRO PRO A1 . n 
A 1 411 GLU 411 411 411 GLU GLU A1 . n 
A 1 412 GLY 412 412 412 GLY GLY A1 . n 
A 1 413 ASP 413 413 413 ASP ASP A1 . n 
A 1 414 TRP 414 414 414 TRP TRP A1 . n 
A 1 415 ILE 415 415 415 ILE ILE A1 . n 
A 1 416 GLN 416 416 416 GLN GLN A1 . n 
A 1 417 ASN 417 417 417 ASN ASN A1 . n 
A 1 418 ILE 418 418 418 ILE ILE A1 . n 
A 1 419 ASN 419 419 419 ASN ASN A1 . n 
A 1 420 PHE 420 420 420 PHE PHE A1 . n 
A 1 421 ASN 421 421 421 ASN ASN A1 . n 
A 1 422 LEU 422 422 422 LEU LEU A1 . n 
A 1 423 PRO 423 423 423 PRO PRO A1 . n 
A 1 424 VAL 424 424 424 VAL VAL A1 . n 
A 1 425 THR 425 425 425 THR THR A1 . n 
A 1 426 ASN 426 426 426 ASN ASN A1 . n 
A 1 427 ASP 427 427 427 ASP ASP A1 . n 
A 1 428 ASN 428 428 428 ASN ASN A1 . n 
A 1 429 VAL 429 429 429 VAL VAL A1 . n 
A 1 430 LEU 430 430 430 LEU LEU A1 . n 
A 1 431 LEU 431 431 431 LEU LEU A1 . n 
A 1 432 PRO 432 432 432 PRO PRO A1 . n 
A 1 433 THR 433 433 433 THR THR A1 . n 
A 1 434 ASP 434 434 434 ASP ASP A1 . n 
A 1 435 PRO 435 435 435 PRO PRO A1 . n 
A 1 436 ILE 436 436 436 ILE ILE A1 . n 
A 1 437 GLY 437 437 437 GLY GLY A1 . n 
A 1 438 GLY 438 438 438 GLY GLY A1 . n 
A 1 439 LYS 439 439 439 LYS LYS A1 . n 
A 1 440 THR 440 440 440 THR THR A1 . n 
A 1 441 GLY 441 441 441 GLY GLY A1 . n 
A 1 442 ILE 442 442 442 ILE ILE A1 . n 
A 1 443 ASN 443 443 443 ASN ASN A1 . n 
A 1 444 TYR 444 444 444 TYR TYR A1 . n 
A 1 445 THR 445 445 445 THR THR A1 . n 
A 1 446 ASN 446 446 446 ASN ASN A1 . n 
A 1 447 ILE 447 447 447 ILE ILE A1 . n 
A 1 448 PHE 448 448 448 PHE PHE A1 . n 
A 1 449 ASN 449 449 449 ASN ASN A1 . n 
A 1 450 THR 450 450 450 THR THR A1 . n 
A 1 451 TYR 451 451 451 TYR TYR A1 . n 
A 1 452 GLY 452 452 452 GLY GLY A1 . n 
A 1 453 PRO 453 453 453 PRO PRO A1 . n 
A 1 454 LEU 454 454 454 LEU LEU A1 . n 
A 1 455 THR 455 455 455 THR THR A1 . n 
A 1 456 ALA 456 456 456 ALA ALA A1 . n 
A 1 457 LEU 457 457 457 LEU LEU A1 . n 
A 1 458 ASN 458 458 458 ASN ASN A1 . n 
A 1 459 ASN 459 459 459 ASN ASN A1 . n 
A 1 460 VAL 460 460 460 VAL VAL A1 . n 
A 1 461 PRO 461 461 461 PRO PRO A1 . n 
A 1 462 PRO 462 462 462 PRO PRO A1 . n 
A 1 463 VAL 463 463 463 VAL VAL A1 . n 
A 1 464 TYR 464 464 464 TYR TYR A1 . n 
A 1 465 PRO 465 465 465 PRO PRO A1 . n 
A 1 466 ASN 466 466 466 ASN ASN A1 . n 
A 1 467 GLY 467 467 467 GLY GLY A1 . n 
A 1 468 GLN 468 468 468 GLN GLN A1 . n 
A 1 469 ILE 469 469 469 ILE ILE A1 . n 
A 1 470 TRP 470 470 470 TRP TRP A1 . n 
A 1 471 ASP 471 471 471 ASP ASP A1 . n 
A 1 472 LYS 472 472 472 LYS LYS A1 . n 
A 1 473 GLU 473 473 473 GLU GLU A1 . n 
A 1 474 PHE 474 474 474 PHE PHE A1 . n 
A 1 475 ASP 475 475 475 ASP ASP A1 . n 
A 1 476 THR 476 476 476 THR THR A1 . n 
A 1 477 ASP 477 477 477 ASP ASP A1 . n 
A 1 478 LEU 478 478 478 LEU LEU A1 . n 
A 1 479 LYS 479 479 479 LYS LYS A1 . n 
A 1 480 PRO 480 480 480 PRO PRO A1 . n 
A 1 481 ARG 481 481 481 ARG ARG A1 . n 
A 1 482 LEU 482 482 482 LEU LEU A1 . n 
A 1 483 HIS 483 483 483 HIS HIS A1 . n 
A 1 484 VAL 484 484 484 VAL VAL A1 . n 
A 1 485 ASN 485 485 485 ASN ASN A1 . n 
A 1 486 ALA 486 486 486 ALA ALA A1 . n 
A 1 487 PRO 487 487 487 PRO PRO A1 . n 
A 1 488 PHE 488 488 488 PHE PHE A1 . n 
A 1 489 VAL 489 489 489 VAL VAL A1 . n 
A 1 490 CYS 490 490 490 CYS CYS A1 . n 
A 1 491 GLN 491 491 491 GLN GLN A1 . n 
A 1 492 ASN 492 492 492 ASN ASN A1 . n 
A 1 493 ASN 493 493 493 ASN ASN A1 . n 
A 1 494 CYS 494 494 494 CYS CYS A1 . n 
A 1 495 PRO 495 495 495 PRO PRO A1 . n 
A 1 496 GLY 496 496 496 GLY GLY A1 . n 
A 1 497 GLN 497 497 497 GLN GLN A1 . n 
A 1 498 LEU 498 498 498 LEU LEU A1 . n 
A 1 499 PHE 499 499 499 PHE PHE A1 . n 
A 1 500 VAL 500 500 500 VAL VAL A1 . n 
A 1 501 LYS 501 501 501 LYS LYS A1 . n 
A 1 502 VAL 502 502 502 VAL VAL A1 . n 
A 1 503 ALA 503 503 503 ALA ALA A1 . n 
A 1 504 PRO 504 504 504 PRO PRO A1 . n 
A 1 505 ASN 505 505 505 ASN ASN A1 . n 
A 1 506 LEU 506 506 506 LEU LEU A1 . n 
A 1 507 THR 507 507 507 THR THR A1 . n 
A 1 508 ASN 508 508 508 ASN ASN A1 . n 
A 1 509 GLU 509 509 509 GLU GLU A1 . n 
A 1 510 TYR 510 510 510 TYR TYR A1 . n 
A 1 511 ASP 511 511 511 ASP ASP A1 . n 
A 1 512 PRO 512 512 512 PRO PRO A1 . n 
A 1 513 ASP 513 513 513 ASP ASP A1 . n 
A 1 514 ALA 514 514 514 ALA ALA A1 . n 
A 1 515 SER 515 515 515 SER SER A1 . n 
A 1 516 ALA 516 516 516 ALA ALA A1 . n 
A 1 517 ASN 517 517 517 ASN ASN A1 . n 
A 1 518 MET 518 518 518 MET MET A1 . n 
A 1 519 SER 519 519 519 SER SER A1 . n 
A 1 520 ARG 520 520 520 ARG ARG A1 . n 
A 1 521 ILE 521 521 521 ILE ILE A1 . n 
A 1 522 VAL 522 522 522 VAL VAL A1 . n 
A 1 523 THR 523 523 523 THR THR A1 . n 
A 1 524 TYR 524 524 524 TYR TYR A1 . n 
A 1 525 SER 525 525 525 SER SER A1 . n 
A 1 526 ASP 526 526 526 ASP ASP A1 . n 
A 1 527 PHE 527 527 527 PHE PHE A1 . n 
A 1 528 TRP 528 528 528 TRP TRP A1 . n 
A 1 529 TRP 529 529 529 TRP TRP A1 . n 
A 1 530 LYS 530 530 530 LYS LYS A1 . n 
A 1 531 GLY 531 531 531 GLY GLY A1 . n 
A 1 532 LYS 532 532 532 LYS LYS A1 . n 
A 1 533 LEU 533 533 533 LEU LEU A1 . n 
A 1 534 VAL 534 534 534 VAL VAL A1 . n 
A 1 535 PHE 535 535 535 PHE PHE A1 . n 
A 1 536 LYS 536 536 536 LYS LYS A1 . n 
A 1 537 ALA 537 537 537 ALA ALA A1 . n 
A 1 538 LYS 538 538 538 LYS LYS A1 . n 
A 1 539 LEU 539 539 539 LEU LEU A1 . n 
A 1 540 ARG 540 540 540 ARG ARG A1 . n 
A 1 541 ALA 541 541 541 ALA ALA A1 . n 
A 1 542 SER 542 542 542 SER SER A1 . n 
A 1 543 HIS 543 543 543 HIS HIS A1 . n 
A 1 544 THR 544 544 544 THR THR A1 . n 
A 1 545 TRP 545 545 545 TRP TRP A1 . n 
A 1 546 ASN 546 546 546 ASN ASN A1 . n 
A 1 547 PRO 547 547 547 PRO PRO A1 . n 
A 1 548 ILE 548 548 548 ILE ILE A1 . n 
A 1 549 GLN 549 549 549 GLN GLN A1 . n 
A 1 550 GLN 550 550 550 GLN GLN A1 . n 
A 1 551 MET 551 551 551 MET MET A1 . n 
A 1 552 SER 552 552 552 SER SER A1 . n 
A 1 553 ILE 553 553 553 ILE ILE A1 . n 
A 1 554 ASN 554 554 554 ASN ASN A1 . n 
A 1 555 VAL 555 555 555 VAL VAL A1 . n 
A 1 556 ASP 556 556 556 ASP ASP A1 . n 
A 1 557 ASN 557 557 557 ASN ASN A1 . n 
A 1 558 GLN 558 558 558 GLN GLN A1 . n 
A 1 559 PHE 559 559 559 PHE PHE A1 . n 
A 1 560 ASN 560 560 560 ASN ASN A1 . n 
A 1 561 TYR 561 561 561 TYR TYR A1 . n 
A 1 562 VAL 562 562 562 VAL VAL A1 . n 
A 1 563 PRO 563 563 563 PRO PRO A1 . n 
A 1 564 SER 564 564 564 SER SER A1 . n 
A 1 565 ASN 565 565 565 ASN ASN A1 . n 
A 1 566 ILE 566 566 566 ILE ILE A1 . n 
A 1 567 GLY 567 567 567 GLY GLY A1 . n 
A 1 568 GLY 568 568 568 GLY GLY A1 . n 
A 1 569 MET 569 569 569 MET MET A1 . n 
A 1 570 LYS 570 570 570 LYS LYS A1 . n 
A 1 571 ILE 571 571 571 ILE ILE A1 . n 
A 1 572 VAL 572 572 572 VAL VAL A1 . n 
A 1 573 TYR 573 573 573 TYR TYR A1 . n 
A 1 574 GLU 574 574 574 GLU GLU A1 . n 
A 1 575 LYS 575 575 575 LYS LYS A1 . n 
A 1 576 SER 576 576 576 SER SER A1 . n 
A 1 577 GLN 577 577 577 GLN GLN A1 . n 
A 1 578 LEU 578 578 578 LEU LEU A1 . n 
A 1 579 ALA 579 579 579 ALA ALA A1 . n 
A 1 580 PRO 580 580 580 PRO PRO A1 . n 
A 1 581 ARG 581 581 581 ARG ARG A1 . n 
A 1 582 LYS 582 582 582 LYS LYS A1 . n 
A 1 583 LEU 583 583 583 LEU LEU A1 . n 
A 1 584 TYR 584 584 584 TYR TYR A1 . n 
B 2 1   ASP 1   1   1   ASP ASP L2 . n 
B 2 2   ILE 2   2   2   ILE ILE L2 . n 
B 2 3   VAL 3   3   3   VAL VAL L2 . n 
B 2 4   MET 4   4   4   MET MET L2 . n 
B 2 5   THR 5   5   5   THR THR L2 . n 
B 2 6   GLN 6   6   6   GLN GLN L2 . n 
B 2 7   SER 7   7   7   SER SER L2 . n 
B 2 8   HIS 8   8   8   HIS HIS L2 . n 
B 2 9   LYS 9   9   9   LYS LYS L2 . n 
B 2 10  PHE 10  10  10  PHE PHE L2 . n 
B 2 11  MET 11  11  11  MET MET L2 . n 
B 2 12  SER 12  12  12  SER SER L2 . n 
B 2 13  THR 13  13  13  THR THR L2 . n 
B 2 14  SER 14  14  14  SER SER L2 . n 
B 2 15  VAL 15  15  15  VAL VAL L2 . n 
B 2 16  GLY 16  16  16  GLY GLY L2 . n 
B 2 17  ASP 17  17  17  ASP ASP L2 . n 
B 2 18  ARG 18  18  18  ARG ARG L2 . n 
B 2 19  VAL 19  19  19  VAL VAL L2 . n 
B 2 20  SER 20  20  20  SER SER L2 . n 
B 2 21  ILE 21  21  21  ILE ILE L2 . n 
B 2 22  THR 22  22  22  THR THR L2 . n 
B 2 23  CYS 23  23  23  CYS CYS L2 . n 
B 2 24  LYS 24  24  24  LYS LYS L2 . n 
B 2 25  ALA 25  25  25  ALA ALA L2 . n 
B 2 26  SER 26  26  26  SER SER L2 . n 
B 2 27  GLN 27  27  27  GLN GLN L2 . n 
B 2 28  ASP 28  28  28  ASP ASP L2 . n 
B 2 29  VAL 29  29  29  VAL VAL L2 . n 
B 2 30  ASN 30  30  30  ASN ASN L2 . n 
B 2 31  THR 31  31  31  THR THR L2 . n 
B 2 32  ALA 32  32  32  ALA ALA L2 . n 
B 2 33  LEU 33  33  33  LEU LEU L2 . n 
B 2 34  ALA 34  34  34  ALA ALA L2 . n 
B 2 35  TRP 35  35  35  TRP TRP L2 . n 
B 2 36  TYR 36  36  36  TYR TYR L2 . n 
B 2 37  GLN 37  37  37  GLN GLN L2 . n 
B 2 38  GLN 38  38  38  GLN GLN L2 . n 
B 2 39  ILE 39  39  39  ILE ILE L2 . n 
B 2 40  PRO 40  40  40  PRO PRO L2 . n 
B 2 41  GLY 41  41  41  GLY GLY L2 . n 
B 2 42  GLN 42  42  42  GLN GLN L2 . n 
B 2 43  SER 43  43  43  SER SER L2 . n 
B 2 44  PRO 44  44  44  PRO PRO L2 . n 
B 2 45  LYS 45  45  45  LYS LYS L2 . n 
B 2 46  LEU 46  46  46  LEU LEU L2 . n 
B 2 47  LEU 47  47  47  LEU LEU L2 . n 
B 2 48  ILE 48  48  48  ILE ILE L2 . n 
B 2 49  TYR 49  49  49  TYR TYR L2 . n 
B 2 50  SER 50  50  50  SER SER L2 . n 
B 2 51  ALA 51  51  51  ALA ALA L2 . n 
B 2 52  SER 52  52  52  SER SER L2 . n 
B 2 53  ASN 53  53  53  ASN ASN L2 . n 
B 2 54  ARG 54  54  54  ARG ARG L2 . n 
B 2 55  TYR 55  55  55  TYR TYR L2 . n 
B 2 56  THR 56  56  56  THR THR L2 . n 
B 2 57  GLY 57  57  57  GLY GLY L2 . n 
B 2 58  VAL 58  58  58  VAL VAL L2 . n 
B 2 59  PRO 59  59  59  PRO PRO L2 . n 
B 2 60  ASP 60  60  60  ASP ASP L2 . n 
B 2 61  ARG 61  61  61  ARG ARG L2 . n 
B 2 62  PHE 62  62  62  PHE PHE L2 . n 
B 2 63  THR 63  63  63  THR THR L2 . n 
B 2 64  ALA 64  64  64  ALA ALA L2 . n 
B 2 65  SER 65  65  65  SER SER L2 . n 
B 2 66  GLY 66  66  66  GLY GLY L2 . n 
B 2 67  SER 67  67  67  SER SER L2 . n 
B 2 68  GLY 68  68  68  GLY GLY L2 . n 
B 2 69  THR 69  69  69  THR THR L2 . n 
B 2 70  ASP 70  70  70  ASP ASP L2 . n 
B 2 71  PHE 71  71  71  PHE PHE L2 . n 
B 2 72  THR 72  72  72  THR THR L2 . n 
B 2 73  PHE 73  73  73  PHE PHE L2 . n 
B 2 74  THR 74  74  74  THR THR L2 . n 
B 2 75  ILE 75  75  75  ILE ILE L2 . n 
B 2 76  SER 76  76  76  SER SER L2 . n 
B 2 77  SER 77  77  77  SER SER L2 . n 
B 2 78  VAL 78  78  78  VAL VAL L2 . n 
B 2 79  GLN 79  79  79  GLN GLN L2 . n 
B 2 80  ALA 80  80  80  ALA ALA L2 . n 
B 2 81  GLU 81  81  81  GLU GLU L2 . n 
B 2 82  ASP 82  82  82  ASP ASP L2 . n 
B 2 83  LEU 83  83  83  LEU LEU L2 . n 
B 2 84  ALA 84  84  84  ALA ALA L2 . n 
B 2 85  LEU 85  85  85  LEU LEU L2 . n 
B 2 86  TYR 86  86  86  TYR TYR L2 . n 
B 2 87  TYR 87  87  87  TYR TYR L2 . n 
B 2 88  CYS 88  88  88  CYS CYS L2 . n 
B 2 89  GLN 89  89  89  GLN GLN L2 . n 
B 2 90  GLN 90  90  90  GLN GLN L2 . n 
B 2 91  HIS 91  91  91  HIS HIS L2 . n 
B 2 92  TYR 92  92  92  TYR TYR L2 . n 
B 2 93  THR 93  93  93  THR THR L2 . n 
B 2 94  THR 94  94  94  THR THR L2 . n 
B 2 95  PRO 95  95  95  PRO PRO L2 . n 
B 2 96  TRP 96  96  96  TRP TRP L2 . n 
B 2 97  THR 97  97  97  THR THR L2 . n 
B 2 98  PHE 98  98  98  PHE PHE L2 . n 
B 2 99  GLY 99  99  99  GLY GLY L2 . n 
B 2 100 GLY 100 100 100 GLY GLY L2 . n 
B 2 101 GLY 101 101 101 GLY GLY L2 . n 
B 2 102 THR 102 102 102 THR THR L2 . n 
B 2 103 LYS 103 103 103 LYS LYS L2 . n 
B 2 104 LEU 104 104 104 LEU LEU L2 . n 
B 2 105 GLU 105 105 105 GLU GLU L2 . n 
B 2 106 ILE 106 106 106 ILE ILE L2 . n 
B 2 107 LYS 107 107 107 LYS LYS L2 . n 
B 2 108 ARG 108 108 108 ARG ARG L2 . n 
C 3 1   ALA 1   1   1   ALA ALA H2 . n 
C 3 2   VAL 2   2   2   VAL VAL H2 . n 
C 3 3   HIS 3   3   3   HIS HIS H2 . n 
C 3 4   LEU 4   4   4   LEU LEU H2 . n 
C 3 5   GLN 5   5   5   GLN GLN H2 . n 
C 3 6   GLY 6   6   6   GLY GLY H2 . n 
C 3 7   THR 7   7   7   THR THR H2 . n 
C 3 8   GLU 8   8   8   GLU GLU H2 . n 
C 3 9   LEU 9   9   9   LEU LEU H2 . n 
C 3 10  VAL 10  10  10  VAL VAL H2 . n 
C 3 11  LYS 11  11  11  LYS LYS H2 . n 
C 3 12  PRO 12  12  12  PRO PRO H2 . n 
C 3 13  GLY 13  13  13  GLY GLY H2 . n 
C 3 14  ALA 14  14  14  ALA ALA H2 . n 
C 3 15  SER 15  15  15  SER SER H2 . n 
C 3 16  ALA 16  16  16  ALA ALA H2 . n 
C 3 17  GLY 17  17  17  GLY GLY H2 . n 
C 3 18  VAL 18  18  18  VAL VAL H2 . n 
C 3 19  LYS 19  19  19  LYS LYS H2 . n 
C 3 20  LEU 20  20  20  LEU LEU H2 . n 
C 3 21  SER 21  21  21  SER SER H2 . n 
C 3 22  CYS 22  22  22  CYS CYS H2 . n 
C 3 23  LYS 23  23  23  LYS LYS H2 . n 
C 3 24  ALA 24  24  24  ALA ALA H2 . n 
C 3 25  SER 25  25  25  SER SER H2 . n 
C 3 26  GLY 26  26  26  GLY GLY H2 . n 
C 3 27  TYR 27  27  27  TYR TYR H2 . n 
C 3 28  THR 28  28  28  THR THR H2 . n 
C 3 29  PHE 29  29  29  PHE PHE H2 . n 
C 3 30  THR 30  30  30  THR THR H2 . n 
C 3 31  ASN 31  31  31  ASN ASN H2 . n 
C 3 32  TYR 32  32  32  TYR TYR H2 . n 
C 3 33  ASP 33  33  33  ASP ASP H2 . n 
C 3 34  MET 34  34  34  MET MET H2 . n 
C 3 35  ASN 35  35  35  ASN ASN H2 . n 
C 3 36  TRP 36  36  36  TRP TRP H2 . n 
C 3 37  VAL 37  37  37  VAL VAL H2 . n 
C 3 38  ARG 38  38  38  ARG ARG H2 . n 
C 3 39  GLN 39  39  39  GLN GLN H2 . n 
C 3 40  ARG 40  40  40  ARG ARG H2 . n 
C 3 41  PRO 41  41  41  PRO PRO H2 . n 
C 3 42  GLU 42  42  42  GLU GLU H2 . n 
C 3 43  GLN 43  43  43  GLN GLN H2 . n 
C 3 44  GLY 44  44  44  GLY GLY H2 . n 
C 3 45  LEU 45  45  45  LEU LEU H2 . n 
C 3 46  GLU 46  46  46  GLU GLU H2 . n 
C 3 47  TRP 47  47  47  TRP TRP H2 . n 
C 3 48  ILE 48  48  48  ILE ILE H2 . n 
C 3 49  GLY 49  49  49  GLY GLY H2 . n 
C 3 50  TRP 50  50  50  TRP TRP H2 . n 
C 3 51  ILE 51  51  51  ILE ILE H2 . n 
C 3 52  PHE 52  52  52  PHE PHE H2 . n 
C 3 53  PRO 53  53  53  PRO PRO H2 . n 
C 3 54  GLY 54  54  54  GLY GLY H2 . n 
C 3 55  ASP 55  55  55  ASP ASP H2 . n 
C 3 56  GLY 56  56  56  GLY GLY H2 . n 
C 3 57  SER 57  57  57  SER SER H2 . n 
C 3 58  THR 58  58  58  THR THR H2 . n 
C 3 59  ARG 59  59  59  ARG ARG H2 . n 
C 3 60  TYR 60  60  60  TYR TYR H2 . n 
C 3 61  ASN 61  61  61  ASN ASN H2 . n 
C 3 62  GLU 62  62  62  GLU GLU H2 . n 
C 3 63  LYS 63  63  63  LYS LYS H2 . n 
C 3 64  PHE 64  64  64  PHE PHE H2 . n 
C 3 65  LYS 65  65  65  LYS LYS H2 . n 
C 3 66  GLY 66  66  66  GLY GLY H2 . n 
C 3 67  LYS 67  67  67  LYS LYS H2 . n 
C 3 68  ALA 68  68  68  ALA ALA H2 . n 
C 3 69  THR 69  69  69  THR THR H2 . n 
C 3 70  LEU 70  70  70  LEU LEU H2 . n 
C 3 71  THR 71  71  71  THR THR H2 . n 
C 3 72  THR 72  72  72  THR THR H2 . n 
C 3 73  ASP 73  73  73  ASP ASP H2 . n 
C 3 74  LYS 74  74  74  LYS LYS H2 . n 
C 3 75  SER 75  75  75  SER SER H2 . n 
C 3 76  SER 76  76  76  SER SER H2 . n 
C 3 77  SER 77  77  77  SER SER H2 . n 
C 3 78  THR 78  78  78  THR THR H2 . n 
C 3 79  ALA 79  79  79  ALA ALA H2 . n 
C 3 80  TYR 80  80  80  TYR TYR H2 . n 
C 3 81  GLN 81  81  81  GLN GLN H2 . n 
C 3 82  LEU 82  82  82  LEU LEU H2 . n 
C 3 83  ASN 83  83  83  ASN ASN H2 . n 
C 3 84  ARG 84  84  84  ARG ARG H2 . n 
C 3 85  LEU 85  85  85  LEU LEU H2 . n 
C 3 86  THR 86  86  86  THR THR H2 . n 
C 3 87  SER 87  87  87  SER SER H2 . n 
C 3 88  GLU 88  88  88  GLU GLU H2 . n 
C 3 89  ASP 89  89  89  ASP ASP H2 . n 
C 3 90  SER 90  90  90  SER SER H2 . n 
C 3 91  ALA 91  91  91  ALA ALA H2 . n 
C 3 92  VAL 92  92  92  VAL VAL H2 . n 
C 3 93  TYR 93  93  93  TYR TYR H2 . n 
C 3 94  PHE 94  94  94  PHE PHE H2 . n 
C 3 95  CYS 95  95  95  CYS CYS H2 . n 
C 3 96  ALA 96  96  96  ALA ALA H2 . n 
C 3 97  ARG 97  97  97  ARG ARG H2 . n 
C 3 98  ARG 98  98  98  ARG ARG H2 . n 
C 3 99  GLY 99  99  99  GLY GLY H2 . n 
C 3 100 SER 100 100 100 SER SER H2 . n 
C 3 101 HIS 101 101 101 HIS HIS H2 . n 
C 3 102 GLY 102 102 102 GLY GLY H2 . n 
C 3 103 SER 103 103 103 SER SER H2 . n 
C 3 104 TYR 104 104 104 TYR TYR H2 . n 
C 3 105 SER 105 105 105 SER SER H2 . n 
C 3 106 PHE 106 106 106 PHE PHE H2 . n 
C 3 107 ALA 107 107 107 ALA ALA H2 . n 
C 3 108 TYR 108 108 108 TYR TYR H2 . n 
C 3 109 TRP 109 109 109 TRP TRP H2 . n 
C 3 110 GLY 110 110 110 GLY GLY H2 . n 
C 3 111 GLN 111 111 111 GLN GLN H2 . n 
C 3 112 GLY 112 112 112 GLY GLY H2 . n 
C 3 113 THR 113 113 113 THR THR H2 . n 
C 3 114 LEU 114 114 114 LEU LEU H2 . n 
C 3 115 VAL 115 115 115 VAL VAL H2 . n 
C 3 116 THR 116 116 116 THR THR H2 . n 
C 3 117 VAL 117 117 117 VAL VAL H2 . n 
C 3 118 SER 118 118 118 SER SER H2 . n 
C 3 119 GLY 119 119 119 GLY GLY H2 . n 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_pdbx_point_symmetry.entry_id             7M3L 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2021-07-28 
2 'Structure model' 1 1 2021-08-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Derived calculations' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' pdbx_struct_assembly     
2 2 'Structure model' pdbx_struct_assembly_gen 
3 2 'Structure model' pdbx_struct_oper_list    
# 
_em_3d_fitting.entry_id          7M3L 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7M3L 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               95353 
_em_3d_reconstruction.resolution                  3.2 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.euler_angles_details        ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.details 
_em_entity_assembly.name 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.entity_id_list 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
1 0 ? 'Canine parvovirus with fab' NATURAL COMPLEX '1, 2, 3' ? ? 
2 1 ? 'Canine parvovirus'          NATURAL COMPLEX 1         ? ? 
3 1 ? Fab14                        NATURAL COMPLEX 2,3       ? ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7M3L 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI POLARA 300' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             ? 
_em_imaging.nominal_defocus_min             ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_virus_entity.entity_assembly_id    1 
_em_virus_entity.empty                 NO 
_em_virus_entity.enveloped             NO 
_em_virus_entity.virus_isolate         SPECIES 
_em_virus_entity.virus_type            VIRION 
_em_virus_entity.id                    1 
_em_virus_entity.virus_host_category   ? 
_em_virus_entity.details               ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7M3L 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7M3L 
_em_experiment.id                      1 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   A1 GLY 227 ? ? CE1 H2 HIS 101 ? ? 1.55 
2 1 OD1 A1 ASN 93  ? ? O   H2 GLY 102 ? ? 1.86 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             C 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A1 
_pdbx_validate_rmsd_angle.auth_comp_id_1             MET 
_pdbx_validate_rmsd_angle.auth_seq_id_1              331 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A1 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_2              332 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A1 
_pdbx_validate_rmsd_angle.auth_comp_id_3             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_3              332 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                137.62 
_pdbx_validate_rmsd_angle.angle_target_value         121.70 
_pdbx_validate_rmsd_angle.angle_deviation            15.92 
_pdbx_validate_rmsd_angle.angle_standard_deviation   2.50 
_pdbx_validate_rmsd_angle.linker_flag                Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A1 47  ? ? -140.49 44.69   
2  1 ASN A1 56  ? ? -54.55  108.78  
3  1 MET A1 87  ? ? -118.71 72.37   
4  1 ASN A1 115 ? ? -100.20 71.89   
5  1 TRP A1 126 ? ? -66.71  -81.98  
6  1 GLN A1 127 ? ? 32.23   -22.11  
7  1 LEU A1 128 ? ? -140.16 -16.91  
8  1 ALA A1 157 ? ? 60.83   67.20   
9  1 GLN A1 159 ? ? -151.59 55.94   
10 1 PRO A1 238 ? ? -82.52  42.60   
11 1 ASN A1 282 ? ? -85.56  43.60   
12 1 ASN A1 292 ? ? -98.83  50.90   
13 1 SER A1 348 ? ? -157.94 -158.88 
14 1 PRO A1 423 ? ? -32.71  128.79  
15 1 ASP A1 475 ? ? -92.07  50.22   
16 1 PRO A1 512 ? ? -89.47  44.48   
17 1 ASN A1 557 ? ? -142.01 28.02   
18 1 ASN A1 565 ? ? 69.90   -14.45  
19 1 ALA L2 32  ? ? 36.15   46.92   
20 1 ALA L2 51  ? ? 65.72   -5.04   
21 1 ALA H2 14  ? ? -93.44  49.60   
22 1 SER H2 15  ? ? -130.79 -37.61  
23 1 ALA H2 16  ? ? -128.76 -167.36 
24 1 ASP H2 89  ? ? -93.16  34.69   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 TRP A1 126 ? ? GLN A1 127 ? ? 133.14  
2 1 THR A1 158 ? ? GLN A1 159 ? ? 143.99  
3 1 GLN A1 159 ? ? PRO A1 160 ? ? 140.03  
4 1 LEU A1 422 ? ? PRO A1 423 ? ? -126.65 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A1 MET 1  ? A MET 1  
2  1 Y 1 A1 SER 2  ? A SER 2  
3  1 Y 1 A1 ASP 3  ? A ASP 3  
4  1 Y 1 A1 GLY 4  ? A GLY 4  
5  1 Y 1 A1 ALA 5  ? A ALA 5  
6  1 Y 1 A1 VAL 6  ? A VAL 6  
7  1 Y 1 A1 GLN 7  ? A GLN 7  
8  1 Y 1 A1 PRO 8  ? A PRO 8  
9  1 Y 1 A1 ASP 9  ? A ASP 9  
10 1 Y 1 A1 GLY 10 ? A GLY 10 
11 1 Y 1 A1 GLY 11 ? A GLY 11 
12 1 Y 1 A1 GLN 12 ? A GLN 12 
13 1 Y 1 A1 PRO 13 ? A PRO 13 
14 1 Y 1 A1 ALA 14 ? A ALA 14 
15 1 Y 1 A1 VAL 15 ? A VAL 15 
16 1 Y 1 A1 ARG 16 ? A ARG 16 
17 1 Y 1 A1 ASN 17 ? A ASN 17 
18 1 Y 1 A1 GLU 18 ? A GLU 18 
19 1 Y 1 A1 ARG 19 ? A ARG 19 
20 1 Y 1 A1 ALA 20 ? A ALA 20 
21 1 Y 1 A1 THR 21 ? A THR 21 
22 1 Y 1 A1 GLY 22 ? A GLY 22 
23 1 Y 1 A1 SER 23 ? A SER 23 
24 1 Y 1 A1 GLY 24 ? A GLY 24 
25 1 Y 1 A1 ASN 25 ? A ASN 25 
26 1 Y 1 A1 GLY 26 ? A GLY 26 
27 1 Y 1 A1 SER 27 ? A SER 27 
28 1 Y 1 A1 GLY 28 ? A GLY 28 
29 1 Y 1 A1 GLY 29 ? A GLY 29 
30 1 Y 1 A1 GLY 30 ? A GLY 30 
31 1 Y 1 A1 GLY 31 ? A GLY 31 
32 1 Y 1 A1 GLY 32 ? A GLY 32 
33 1 Y 1 A1 GLY 33 ? A GLY 33 
34 1 Y 1 A1 GLY 34 ? A GLY 34 
35 1 Y 1 A1 SER 35 ? A SER 35 
36 1 Y 1 A1 GLY 36 ? A GLY 36 
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
loop_
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
2 2 ? ? 10788 ? ? 'Canine parvovirus' ? ? 
3 3 ? ? 10090 ? ? 'Mus musculus'      ? ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                            1 
_em_image_recording.imaging_id                    1 
_em_image_recording.avg_electron_dose_per_image   60 
_em_image_recording.average_exposure_time         ? 
_em_image_recording.details                       ? 
_em_image_recording.detector_mode                 ? 
_em_image_recording.film_or_detector_model        'FEI FALCON III (4k x 4k)' 
_em_image_recording.num_diffraction_images        ? 
_em_image_recording.num_grids_imaged              ? 
_em_image_recording.num_real_images               ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'PARTICLE SELECTION'       ? ? ? 1 ? ? 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/Office of the Director' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           S10RR031780 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   microscopy 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
