data_7T75
# 
_entry.id   7T75 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.361 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7T75         pdb_00007t75 10.2210/pdb7t75/pdb 
WWPDB D_1000259225 ?            ?                   
EMDB  EMD-25734    ?            ?                   
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB . EMD-25734 'associated EM volume' 
EMDB . EMD-25732 'other EM volume'      
EMDB . EMD-25733 'other EM volume'      
EMDB . EMD-25735 'other EM volume'      
EMDB . EMD-25736 'other EM volume'      
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7T75 
_pdbx_database_status.recvd_initial_deposition_date   2021-12-14 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_audit_author.name               'Berndsen, Z.T.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0003-4531-9907 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Immunity 
_citation.journal_id_ASTM           IUNIEH 
_citation.journal_id_CSD            2048 
_citation.journal_id_ISSN           1074-7613 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
;
_citation.year                      2022 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Willis, J.R.'      1  ?                   
primary 'Berndsen, Z.T.'    2  0000-0003-4531-9907 
primary 'Ma, K.M.'          3  ?                   
primary 'Steichen, J.M.'    4  ?                   
primary 'Schifner, T.'      5  ?                   
primary 'Landais, E.'       6  ?                   
primary 'Liguori, A.'       7  ?                   
primary 'Kalyuzhniy, O.'    8  ?                   
primary 'Allen, J.D.'       9  ?                   
primary 'Baboo, S.'         10 ?                   
primary 'Omorodion, O.'     11 ?                   
primary 'Diedrich, J.K.'    12 ?                   
primary 'Hu, X.'            13 ?                   
primary 'Georgeson, E.'     14 ?                   
primary 'Phelps, N.'        15 ?                   
primary 'Eskandarzadeh, S.' 16 ?                   
primary 'Groschel, B.'      17 ?                   
primary 'Kubitz, M.'        18 ?                   
primary 'Adachi, Y.'        19 ?                   
primary 'Mullin, T.M.'      20 ?                   
primary 'Alavi, N.'         21 ?                   
primary 'Falcone, S.'       22 ?                   
primary 'Himansu, S.'       23 ?                   
primary 'Carfi, A.'         24 ?                   
primary 'Wilson, I.A.'      25 ?                   
primary 'Yates III, J.R.'   26 ?                   
primary 'Paulson, J.C.'     27 ?                   
primary 'Crispin, M.'       28 ?                   
primary 'Ward, A.B.'        29 0000-0001-7153-3769 
primary 'Schief, W.'        30 0000-0002-1120-0150 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'HIV Envelope ApexGT2 gp120' 56123.020 1  ? ? ? ? 
2 polymer     man 'HIV Envelope ApexGT2 gp41' 18250.541 1  ? ? ? ? 
3 polymer     man 'RM20A3 Fab Heavy Chain' 13511.111 1  ? ? ? ? 
4 polymer     man 'RM20A3 Fab Light Chain' 13508.800 1  ? ? ? ? 
5 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3  ? ? ? ? 
6 branched    man 
;alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
748.682   1  ? ? ? ? 
7 branched    man 'alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose' 367.349   2  ? ? ? ? 
8 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   15 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGILPSPGMPALLSLVSLLSVLLMGCVAETGAENLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDP
NPQEIHLENVTEEFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLQCTNVTNNITDDMRGELKNCSFNATTELRN
KRQKVYSLFYRLDIVPMGENSTNYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQC
THGIKPVVSTQLLLNGSLAEEEVIIRSENITNNAKNILVQLNTPVQINCTRPNNNTVKSIRIGPGQAFYYTGDIIGDIRQ
AHCNVSKATWNETLGKVVKQLRKHFGNNTIIRFAQSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNTSVQGSNSTG
SNDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRDNWRSELYKYKVV
KIEPLGVAPTRCKRRVVGRRRRRR
;
;MGILPSPGMPALLSLVSLLSVLLMGCVAETGAENLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDP
NPQEIHLENVTEEFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLQCTNVTNNITDDMRGELKNCSFNATTELRN
KRQKVYSLFYRLDIVPMGENSTNYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQC
THGIKPVVSTQLLLNGSLAEEEVIIRSENITNNAKNILVQLNTPVQINCTRPNNNTVKSIRIGPGQAFYYTGDIIGDIRQ
AHCNVSKATWNETLGKVVKQLRKHFGNNTIIRFAQSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNTSVQGSNSTG
SNDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRDNWRSELYKYKVV
KIEPLGVAPTRCKRRVVGRRRRRR
;
A ? 
2 'polypeptide(L)' no no 
;AVGIGAVSLGFLGAAGSTMGAASMTLTVQARNLLSGIVQQQSNLLRAPEPQQHLLKDTHWGIKQLQARVLAVEHYLRDQQ
LLGIWGCSGKLICCTNVPWNSSWSNRNLSEIWDNMTWLQWDKEISNYTQIIYGLLEESQNQQEKNEQDLLALDGTKHHHH
HH
;
;AVGIGAVSLGFLGAAGSTMGAASMTLTVQARNLLSGIVQQQSNLLRAPEPQQHLLKDTHWGIKQLQARVLAVEHYLRDQQ
LLGIWGCSGKLICCTNVPWNSSWSNRNLSEIWDNMTWLQWDKEISNYTQIIYGLLEESQNQQEKNEQDLLALDGTKHHHH
HH
;
B ? 
3 'polypeptide(L)' no no 
;EVQLVETGGGLVQPGGSLKLSCRASGYTFSSFAMSWVRQAPGKGLEWVSLINDRGGLTFYVDSVKGRFTISRDNSKNTLS
LQMHSLRDGDTAVYYCATGGMSSALQSSKYYFDFWGQGALVTVSS
;
;EVQLVETGGGLVQPGGSLKLSCRASGYTFSSFAMSWVRQAPGKGLEWVSLINDRGGLTFYVDSVKGRFTISRDNSKNTLS
LQMHSLRDGDTAVYYCATGGMSSALQSSKYYFDFWGQGALVTVSS
;
H ? 
4 'polypeptide(L)' no no 
;ALTQPPSVSGSPGQSVTISCTGTSSDIGSYNYVSWYQQHPGKAPKLMIYDVTQRPSGVSDRFSGSKSGNTASLTISGLQA
DDEADYYCSAYAGRQTFYIFGGGTRLTVLGQPKASPTVTLFPPSSEEL
;
;ALTQPPSVSGSPGQSVTISCTGTSSDIGSYNYVSWYQQHPGKAPKLMIYDVTQRPSGVSDRFSGSKSGNTASLTISGLQA
DDEADYYCSAYAGRQTFYIFGGGTRLTVLGQPKASPTVTLFPPSSEEL
;
L ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   ILE n 
1 4   LEU n 
1 5   PRO n 
1 6   SER n 
1 7   PRO n 
1 8   GLY n 
1 9   MET n 
1 10  PRO n 
1 11  ALA n 
1 12  LEU n 
1 13  LEU n 
1 14  SER n 
1 15  LEU n 
1 16  VAL n 
1 17  SER n 
1 18  LEU n 
1 19  LEU n 
1 20  SER n 
1 21  VAL n 
1 22  LEU n 
1 23  LEU n 
1 24  MET n 
1 25  GLY n 
1 26  CYS n 
1 27  VAL n 
1 28  ALA n 
1 29  GLU n 
1 30  THR n 
1 31  GLY n 
1 32  ALA n 
1 33  GLU n 
1 34  ASN n 
1 35  LEU n 
1 36  TRP n 
1 37  VAL n 
1 38  THR n 
1 39  VAL n 
1 40  TYR n 
1 41  TYR n 
1 42  GLY n 
1 43  VAL n 
1 44  PRO n 
1 45  VAL n 
1 46  TRP n 
1 47  LYS n 
1 48  ASP n 
1 49  ALA n 
1 50  GLU n 
1 51  THR n 
1 52  THR n 
1 53  LEU n 
1 54  PHE n 
1 55  CYS n 
1 56  ALA n 
1 57  SER n 
1 58  ASP n 
1 59  ALA n 
1 60  LYS n 
1 61  ALA n 
1 62  TYR n 
1 63  GLU n 
1 64  THR n 
1 65  GLU n 
1 66  LYS n 
1 67  HIS n 
1 68  ASN n 
1 69  VAL n 
1 70  TRP n 
1 71  ALA n 
1 72  THR n 
1 73  HIS n 
1 74  ALA n 
1 75  CYS n 
1 76  VAL n 
1 77  PRO n 
1 78  THR n 
1 79  ASP n 
1 80  PRO n 
1 81  ASN n 
1 82  PRO n 
1 83  GLN n 
1 84  GLU n 
1 85  ILE n 
1 86  HIS n 
1 87  LEU n 
1 88  GLU n 
1 89  ASN n 
1 90  VAL n 
1 91  THR n 
1 92  GLU n 
1 93  GLU n 
1 94  PHE n 
1 95  ASN n 
1 96  MET n 
1 97  TRP n 
1 98  LYS n 
1 99  ASN n 
1 100 ASN n 
1 101 MET n 
1 102 VAL n 
1 103 GLU n 
1 104 GLN n 
1 105 MET n 
1 106 HIS n 
1 107 GLU n 
1 108 ASP n 
1 109 ILE n 
1 110 ILE n 
1 111 SER n 
1 112 LEU n 
1 113 TRP n 
1 114 ASP n 
1 115 GLN n 
1 116 SER n 
1 117 LEU n 
1 118 LYS n 
1 119 PRO n 
1 120 CYS n 
1 121 VAL n 
1 122 LYS n 
1 123 LEU n 
1 124 THR n 
1 125 PRO n 
1 126 LEU n 
1 127 CYS n 
1 128 VAL n 
1 129 THR n 
1 130 LEU n 
1 131 GLN n 
1 132 CYS n 
1 133 THR n 
1 134 ASN n 
1 135 VAL n 
1 136 THR n 
1 137 ASN n 
1 138 ASN n 
1 139 ILE n 
1 140 THR n 
1 141 ASP n 
1 142 ASP n 
1 143 MET n 
1 144 ARG n 
1 145 GLY n 
1 146 GLU n 
1 147 LEU n 
1 148 LYS n 
1 149 ASN n 
1 150 CYS n 
1 151 SER n 
1 152 PHE n 
1 153 ASN n 
1 154 ALA n 
1 155 THR n 
1 156 THR n 
1 157 GLU n 
1 158 LEU n 
1 159 ARG n 
1 160 ASN n 
1 161 LYS n 
1 162 ARG n 
1 163 GLN n 
1 164 LYS n 
1 165 VAL n 
1 166 TYR n 
1 167 SER n 
1 168 LEU n 
1 169 PHE n 
1 170 TYR n 
1 171 ARG n 
1 172 LEU n 
1 173 ASP n 
1 174 ILE n 
1 175 VAL n 
1 176 PRO n 
1 177 MET n 
1 178 GLY n 
1 179 GLU n 
1 180 ASN n 
1 181 SER n 
1 182 THR n 
1 183 ASN n 
1 184 TYR n 
1 185 ARG n 
1 186 LEU n 
1 187 ILE n 
1 188 ASN n 
1 189 CYS n 
1 190 ASN n 
1 191 THR n 
1 192 SER n 
1 193 ALA n 
1 194 ILE n 
1 195 THR n 
1 196 GLN n 
1 197 ALA n 
1 198 CYS n 
1 199 PRO n 
1 200 LYS n 
1 201 VAL n 
1 202 SER n 
1 203 PHE n 
1 204 GLU n 
1 205 PRO n 
1 206 ILE n 
1 207 PRO n 
1 208 ILE n 
1 209 HIS n 
1 210 TYR n 
1 211 CYS n 
1 212 ALA n 
1 213 PRO n 
1 214 ALA n 
1 215 GLY n 
1 216 PHE n 
1 217 ALA n 
1 218 ILE n 
1 219 LEU n 
1 220 LYS n 
1 221 CYS n 
1 222 LYS n 
1 223 ASP n 
1 224 LYS n 
1 225 LYS n 
1 226 PHE n 
1 227 ASN n 
1 228 GLY n 
1 229 THR n 
1 230 GLY n 
1 231 PRO n 
1 232 CYS n 
1 233 PRO n 
1 234 SER n 
1 235 VAL n 
1 236 SER n 
1 237 THR n 
1 238 VAL n 
1 239 GLN n 
1 240 CYS n 
1 241 THR n 
1 242 HIS n 
1 243 GLY n 
1 244 ILE n 
1 245 LYS n 
1 246 PRO n 
1 247 VAL n 
1 248 VAL n 
1 249 SER n 
1 250 THR n 
1 251 GLN n 
1 252 LEU n 
1 253 LEU n 
1 254 LEU n 
1 255 ASN n 
1 256 GLY n 
1 257 SER n 
1 258 LEU n 
1 259 ALA n 
1 260 GLU n 
1 261 GLU n 
1 262 GLU n 
1 263 VAL n 
1 264 ILE n 
1 265 ILE n 
1 266 ARG n 
1 267 SER n 
1 268 GLU n 
1 269 ASN n 
1 270 ILE n 
1 271 THR n 
1 272 ASN n 
1 273 ASN n 
1 274 ALA n 
1 275 LYS n 
1 276 ASN n 
1 277 ILE n 
1 278 LEU n 
1 279 VAL n 
1 280 GLN n 
1 281 LEU n 
1 282 ASN n 
1 283 THR n 
1 284 PRO n 
1 285 VAL n 
1 286 GLN n 
1 287 ILE n 
1 288 ASN n 
1 289 CYS n 
1 290 THR n 
1 291 ARG n 
1 292 PRO n 
1 293 ASN n 
1 294 ASN n 
1 295 ASN n 
1 296 THR n 
1 297 VAL n 
1 298 LYS n 
1 299 SER n 
1 300 ILE n 
1 301 ARG n 
1 302 ILE n 
1 303 GLY n 
1 304 PRO n 
1 305 GLY n 
1 306 GLN n 
1 307 ALA n 
1 308 PHE n 
1 309 TYR n 
1 310 TYR n 
1 311 THR n 
1 312 GLY n 
1 313 ASP n 
1 314 ILE n 
1 315 ILE n 
1 316 GLY n 
1 317 ASP n 
1 318 ILE n 
1 319 ARG n 
1 320 GLN n 
1 321 ALA n 
1 322 HIS n 
1 323 CYS n 
1 324 ASN n 
1 325 VAL n 
1 326 SER n 
1 327 LYS n 
1 328 ALA n 
1 329 THR n 
1 330 TRP n 
1 331 ASN n 
1 332 GLU n 
1 333 THR n 
1 334 LEU n 
1 335 GLY n 
1 336 LYS n 
1 337 VAL n 
1 338 VAL n 
1 339 LYS n 
1 340 GLN n 
1 341 LEU n 
1 342 ARG n 
1 343 LYS n 
1 344 HIS n 
1 345 PHE n 
1 346 GLY n 
1 347 ASN n 
1 348 ASN n 
1 349 THR n 
1 350 ILE n 
1 351 ILE n 
1 352 ARG n 
1 353 PHE n 
1 354 ALA n 
1 355 GLN n 
1 356 SER n 
1 357 SER n 
1 358 GLY n 
1 359 GLY n 
1 360 ASP n 
1 361 LEU n 
1 362 GLU n 
1 363 VAL n 
1 364 THR n 
1 365 THR n 
1 366 HIS n 
1 367 SER n 
1 368 PHE n 
1 369 ASN n 
1 370 CYS n 
1 371 GLY n 
1 372 GLY n 
1 373 GLU n 
1 374 PHE n 
1 375 PHE n 
1 376 TYR n 
1 377 CYS n 
1 378 ASN n 
1 379 THR n 
1 380 SER n 
1 381 GLY n 
1 382 LEU n 
1 383 PHE n 
1 384 ASN n 
1 385 SER n 
1 386 THR n 
1 387 TRP n 
1 388 ILE n 
1 389 SER n 
1 390 ASN n 
1 391 THR n 
1 392 SER n 
1 393 VAL n 
1 394 GLN n 
1 395 GLY n 
1 396 SER n 
1 397 ASN n 
1 398 SER n 
1 399 THR n 
1 400 GLY n 
1 401 SER n 
1 402 ASN n 
1 403 ASP n 
1 404 SER n 
1 405 ILE n 
1 406 THR n 
1 407 LEU n 
1 408 PRO n 
1 409 CYS n 
1 410 ARG n 
1 411 ILE n 
1 412 LYS n 
1 413 GLN n 
1 414 ILE n 
1 415 ILE n 
1 416 ASN n 
1 417 MET n 
1 418 TRP n 
1 419 GLN n 
1 420 ARG n 
1 421 ILE n 
1 422 GLY n 
1 423 GLN n 
1 424 ALA n 
1 425 MET n 
1 426 TYR n 
1 427 ALA n 
1 428 PRO n 
1 429 PRO n 
1 430 ILE n 
1 431 GLN n 
1 432 GLY n 
1 433 VAL n 
1 434 ILE n 
1 435 ARG n 
1 436 CYS n 
1 437 VAL n 
1 438 SER n 
1 439 ASN n 
1 440 ILE n 
1 441 THR n 
1 442 GLY n 
1 443 LEU n 
1 444 ILE n 
1 445 LEU n 
1 446 THR n 
1 447 ARG n 
1 448 ASP n 
1 449 GLY n 
1 450 GLY n 
1 451 SER n 
1 452 THR n 
1 453 ASN n 
1 454 SER n 
1 455 THR n 
1 456 THR n 
1 457 GLU n 
1 458 THR n 
1 459 PHE n 
1 460 ARG n 
1 461 PRO n 
1 462 GLY n 
1 463 GLY n 
1 464 GLY n 
1 465 ASP n 
1 466 MET n 
1 467 ARG n 
1 468 ASP n 
1 469 ASN n 
1 470 TRP n 
1 471 ARG n 
1 472 SER n 
1 473 GLU n 
1 474 LEU n 
1 475 TYR n 
1 476 LYS n 
1 477 TYR n 
1 478 LYS n 
1 479 VAL n 
1 480 VAL n 
1 481 LYS n 
1 482 ILE n 
1 483 GLU n 
1 484 PRO n 
1 485 LEU n 
1 486 GLY n 
1 487 VAL n 
1 488 ALA n 
1 489 PRO n 
1 490 THR n 
1 491 ARG n 
1 492 CYS n 
1 493 LYS n 
1 494 ARG n 
1 495 ARG n 
1 496 VAL n 
1 497 VAL n 
1 498 GLY n 
1 499 ARG n 
1 500 ARG n 
1 501 ARG n 
1 502 ARG n 
1 503 ARG n 
1 504 ARG n 
2 1   ALA n 
2 2   VAL n 
2 3   GLY n 
2 4   ILE n 
2 5   GLY n 
2 6   ALA n 
2 7   VAL n 
2 8   SER n 
2 9   LEU n 
2 10  GLY n 
2 11  PHE n 
2 12  LEU n 
2 13  GLY n 
2 14  ALA n 
2 15  ALA n 
2 16  GLY n 
2 17  SER n 
2 18  THR n 
2 19  MET n 
2 20  GLY n 
2 21  ALA n 
2 22  ALA n 
2 23  SER n 
2 24  MET n 
2 25  THR n 
2 26  LEU n 
2 27  THR n 
2 28  VAL n 
2 29  GLN n 
2 30  ALA n 
2 31  ARG n 
2 32  ASN n 
2 33  LEU n 
2 34  LEU n 
2 35  SER n 
2 36  GLY n 
2 37  ILE n 
2 38  VAL n 
2 39  GLN n 
2 40  GLN n 
2 41  GLN n 
2 42  SER n 
2 43  ASN n 
2 44  LEU n 
2 45  LEU n 
2 46  ARG n 
2 47  ALA n 
2 48  PRO n 
2 49  GLU n 
2 50  PRO n 
2 51  GLN n 
2 52  GLN n 
2 53  HIS n 
2 54  LEU n 
2 55  LEU n 
2 56  LYS n 
2 57  ASP n 
2 58  THR n 
2 59  HIS n 
2 60  TRP n 
2 61  GLY n 
2 62  ILE n 
2 63  LYS n 
2 64  GLN n 
2 65  LEU n 
2 66  GLN n 
2 67  ALA n 
2 68  ARG n 
2 69  VAL n 
2 70  LEU n 
2 71  ALA n 
2 72  VAL n 
2 73  GLU n 
2 74  HIS n 
2 75  TYR n 
2 76  LEU n 
2 77  ARG n 
2 78  ASP n 
2 79  GLN n 
2 80  GLN n 
2 81  LEU n 
2 82  LEU n 
2 83  GLY n 
2 84  ILE n 
2 85  TRP n 
2 86  GLY n 
2 87  CYS n 
2 88  SER n 
2 89  GLY n 
2 90  LYS n 
2 91  LEU n 
2 92  ILE n 
2 93  CYS n 
2 94  CYS n 
2 95  THR n 
2 96  ASN n 
2 97  VAL n 
2 98  PRO n 
2 99  TRP n 
2 100 ASN n 
2 101 SER n 
2 102 SER n 
2 103 TRP n 
2 104 SER n 
2 105 ASN n 
2 106 ARG n 
2 107 ASN n 
2 108 LEU n 
2 109 SER n 
2 110 GLU n 
2 111 ILE n 
2 112 TRP n 
2 113 ASP n 
2 114 ASN n 
2 115 MET n 
2 116 THR n 
2 117 TRP n 
2 118 LEU n 
2 119 GLN n 
2 120 TRP n 
2 121 ASP n 
2 122 LYS n 
2 123 GLU n 
2 124 ILE n 
2 125 SER n 
2 126 ASN n 
2 127 TYR n 
2 128 THR n 
2 129 GLN n 
2 130 ILE n 
2 131 ILE n 
2 132 TYR n 
2 133 GLY n 
2 134 LEU n 
2 135 LEU n 
2 136 GLU n 
2 137 GLU n 
2 138 SER n 
2 139 GLN n 
2 140 ASN n 
2 141 GLN n 
2 142 GLN n 
2 143 GLU n 
2 144 LYS n 
2 145 ASN n 
2 146 GLU n 
2 147 GLN n 
2 148 ASP n 
2 149 LEU n 
2 150 LEU n 
2 151 ALA n 
2 152 LEU n 
2 153 ASP n 
2 154 GLY n 
2 155 THR n 
2 156 LYS n 
2 157 HIS n 
2 158 HIS n 
2 159 HIS n 
2 160 HIS n 
2 161 HIS n 
2 162 HIS n 
3 1   GLU n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLU n 
3 7   THR n 
3 8   GLY n 
3 9   GLY n 
3 10  GLY n 
3 11  LEU n 
3 12  VAL n 
3 13  GLN n 
3 14  PRO n 
3 15  GLY n 
3 16  GLY n 
3 17  SER n 
3 18  LEU n 
3 19  LYS n 
3 20  LEU n 
3 21  SER n 
3 22  CYS n 
3 23  ARG n 
3 24  ALA n 
3 25  SER n 
3 26  GLY n 
3 27  TYR n 
3 28  THR n 
3 29  PHE n 
3 30  SER n 
3 31  SER n 
3 32  PHE n 
3 33  ALA n 
3 34  MET n 
3 35  SER n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ALA n 
3 41  PRO n 
3 42  GLY n 
3 43  LYS n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  VAL n 
3 49  SER n 
3 50  LEU n 
3 51  ILE n 
3 52  ASN n 
3 53  ASP n 
3 54  ARG n 
3 55  GLY n 
3 56  GLY n 
3 57  LEU n 
3 58  THR n 
3 59  PHE n 
3 60  TYR n 
3 61  VAL n 
3 62  ASP n 
3 63  SER n 
3 64  VAL n 
3 65  LYS n 
3 66  GLY n 
3 67  ARG n 
3 68  PHE n 
3 69  THR n 
3 70  ILE n 
3 71  SER n 
3 72  ARG n 
3 73  ASP n 
3 74  ASN n 
3 75  SER n 
3 76  LYS n 
3 77  ASN n 
3 78  THR n 
3 79  LEU n 
3 80  SER n 
3 81  LEU n 
3 82  GLN n 
3 83  MET n 
3 84  HIS n 
3 85  SER n 
3 86  LEU n 
3 87  ARG n 
3 88  ASP n 
3 89  GLY n 
3 90  ASP n 
3 91  THR n 
3 92  ALA n 
3 93  VAL n 
3 94  TYR n 
3 95  TYR n 
3 96  CYS n 
3 97  ALA n 
3 98  THR n 
3 99  GLY n 
3 100 GLY n 
3 101 MET n 
3 102 SER n 
3 103 SER n 
3 104 ALA n 
3 105 LEU n 
3 106 GLN n 
3 107 SER n 
3 108 SER n 
3 109 LYS n 
3 110 TYR n 
3 111 TYR n 
3 112 PHE n 
3 113 ASP n 
3 114 PHE n 
3 115 TRP n 
3 116 GLY n 
3 117 GLN n 
3 118 GLY n 
3 119 ALA n 
3 120 LEU n 
3 121 VAL n 
3 122 THR n 
3 123 VAL n 
3 124 SER n 
3 125 SER n 
4 1   ALA n 
4 2   LEU n 
4 3   THR n 
4 4   GLN n 
4 5   PRO n 
4 6   PRO n 
4 7   SER n 
4 8   VAL n 
4 9   SER n 
4 10  GLY n 
4 11  SER n 
4 12  PRO n 
4 13  GLY n 
4 14  GLN n 
4 15  SER n 
4 16  VAL n 
4 17  THR n 
4 18  ILE n 
4 19  SER n 
4 20  CYS n 
4 21  THR n 
4 22  GLY n 
4 23  THR n 
4 24  SER n 
4 25  SER n 
4 26  ASP n 
4 27  ILE n 
4 28  GLY n 
4 29  SER n 
4 30  TYR n 
4 31  ASN n 
4 32  TYR n 
4 33  VAL n 
4 34  SER n 
4 35  TRP n 
4 36  TYR n 
4 37  GLN n 
4 38  GLN n 
4 39  HIS n 
4 40  PRO n 
4 41  GLY n 
4 42  LYS n 
4 43  ALA n 
4 44  PRO n 
4 45  LYS n 
4 46  LEU n 
4 47  MET n 
4 48  ILE n 
4 49  TYR n 
4 50  ASP n 
4 51  VAL n 
4 52  THR n 
4 53  GLN n 
4 54  ARG n 
4 55  PRO n 
4 56  SER n 
4 57  GLY n 
4 58  VAL n 
4 59  SER n 
4 60  ASP n 
4 61  ARG n 
4 62  PHE n 
4 63  SER n 
4 64  GLY n 
4 65  SER n 
4 66  LYS n 
4 67  SER n 
4 68  GLY n 
4 69  ASN n 
4 70  THR n 
4 71  ALA n 
4 72  SER n 
4 73  LEU n 
4 74  THR n 
4 75  ILE n 
4 76  SER n 
4 77  GLY n 
4 78  LEU n 
4 79  GLN n 
4 80  ALA n 
4 81  ASP n 
4 82  ASP n 
4 83  GLU n 
4 84  ALA n 
4 85  ASP n 
4 86  TYR n 
4 87  TYR n 
4 88  CYS n 
4 89  SER n 
4 90  ALA n 
4 91  TYR n 
4 92  ALA n 
4 93  GLY n 
4 94  ARG n 
4 95  GLN n 
4 96  THR n 
4 97  PHE n 
4 98  TYR n 
4 99  ILE n 
4 100 PHE n 
4 101 GLY n 
4 102 GLY n 
4 103 GLY n 
4 104 THR n 
4 105 ARG n 
4 106 LEU n 
4 107 THR n 
4 108 VAL n 
4 109 LEU n 
4 110 GLY n 
4 111 GLN n 
4 112 PRO n 
4 113 LYS n 
4 114 ALA n 
4 115 SER n 
4 116 PRO n 
4 117 THR n 
4 118 VAL n 
4 119 THR n 
4 120 LEU n 
4 121 PHE n 
4 122 PRO n 
4 123 PRO n 
4 124 SER n 
4 125 SER n 
4 126 GLU n 
4 127 GLU n 
4 128 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 504 HIV-1 ? ? ? ? ? ? ? ? 'Human immunodeficiency virus 1' 11676 ? ? ? ? ? ? ? Human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 162 HIV-1 ? ? ? ? ? ? ? ? 'Human immunodeficiency virus 1' 11676 ? ? ? ? ? ? ? Human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 125 Human ? ? ? ? ? ? ? ? 'Homo sapiens'                   9606  ? ? ? ? ? ? ? Human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 128 Human ? ? ? ? ? ? ? ? 'Homo sapiens'                   9606  ? ? ? ? ? ? ? Human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7T75 7T75 ? 1 ? 1 
2 PDB 7T75 7T75 ? 2 ? 1 
3 PDB 7T75 7T75 ? 3 ? 1 
4 PDB 7T75 7T75 ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7T75 A 1 ? 504 ? 7T75 0   ? 513 ? 0   513 
2 2 7T75 B 1 ? 162 ? 7T75 510 ? 673 ? 510 673 
3 3 7T75 H 1 ? 125 ? 7T75 1   ? 113 ? 1   113 
4 4 7T75 L 1 ? 128 ? 7T75 3   ? 126 ? 3   126 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose                     
'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose' 'C6 H12 O5'      164.156 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7T75 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7T75 
_struct.title                        'HIV-1 Envelope ApexGT2 in complex with RM20A3 Fab' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7T75 
_struct_keywords.text            'HIV, germline targeting vaccine, VIRAL PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 6 ? 
H N N 5 ? 
I N N 7 ? 
J N N 7 ? 
K N N 8 ? 
L N N 8 ? 
M N N 8 ? 
N N N 8 ? 
O N N 8 ? 
P N N 8 ? 
Q N N 8 ? 
R N N 8 ? 
S N N 8 ? 
T N N 8 ? 
U N N 8 ? 
V N N 8 ? 
W N N 8 ? 
X N N 8 ? 
Y N N 8 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 99  ? SER A 116 ? ASN A 98  SER A 115 1 ? 18 
HELX_P HELX_P2  AA2 THR A 140 ? ARG A 144 ? THR A 139 ARG A 143 5 ? 5  
HELX_P HELX_P3  AA3 LYS A 327 ? ARG A 342 ? LYS A 335 ARG A 350 1 ? 16 
HELX_P HELX_P4  AA4 ASP A 360 ? THR A 365 ? ASP A 368 THR A 373 1 ? 6  
HELX_P HELX_P5  AA5 MET A 466 ? TYR A 475 ? MET A 475 TYR A 484 1 ? 10 
HELX_P HELX_P6  AA6 LEU B 12  ? SER B 17  ? LEU B 521 SER B 526 5 ? 6  
HELX_P HELX_P7  AA7 THR B 18  ? SER B 23  ? THR B 527 SER B 532 1 ? 6  
HELX_P HELX_P8  AA8 THR B 25  ? ARG B 31  ? THR B 534 ARG B 540 1 ? 7  
HELX_P HELX_P9  AA9 GLY B 61  ? TRP B 85  ? GLY B 572 TRP B 596 1 ? 25 
HELX_P HELX_P10 AB1 ASN B 107 ? ASP B 113 ? ASN B 618 ASP B 624 1 ? 7  
HELX_P HELX_P11 AB2 THR B 116 ? SER B 125 ? THR B 627 SER B 636 1 ? 10 
HELX_P HELX_P12 AB3 TYR B 127 ? ASP B 148 ? TYR B 638 ASP B 659 1 ? 22 
HELX_P HELX_P13 AB4 THR C 28  ? PHE C 32  ? THR H 28  PHE H 32  5 ? 5  
HELX_P HELX_P14 AB5 ASP C 62  ? LYS C 65  ? ASP H 61  LYS H 64  5 ? 4  
HELX_P HELX_P15 AB6 ARG C 87  ? THR C 91  ? ARG H 83  THR H 87  5 ? 5  
HELX_P HELX_P16 AB7 GLN D 79  ? GLU D 83  ? GLN L 79  GLU L 83  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 120 SG  ? ? ? 1_555 A CYS 198 SG ? ? A CYS 119 A CYS 205 1_555 ? ? ? ? ? ? ? 2.064 ? ?               
disulf2  disulf ?    ? A CYS 127 SG  ? ? ? 1_555 A CYS 189 SG ? ? A CYS 126 A CYS 196 1_555 ? ? ? ? ? ? ? 2.051 ? ?               
disulf3  disulf ?    ? A CYS 132 SG  ? ? ? 1_555 A CYS 150 SG ? ? A CYS 131 A CYS 157 1_555 ? ? ? ? ? ? ? 2.042 ? ?               
disulf4  disulf ?    ? A CYS 211 SG  ? ? ? 1_555 A CYS 240 SG ? ? A CYS 218 A CYS 247 1_555 ? ? ? ? ? ? ? 2.047 ? ?               
disulf5  disulf ?    ? A CYS 221 SG  ? ? ? 1_555 A CYS 232 SG ? ? A CYS 228 A CYS 239 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf6  disulf ?    ? A CYS 289 SG  ? ? ? 1_555 A CYS 323 SG ? ? A CYS 296 A CYS 331 1_555 ? ? ? ? ? ? ? 2.027 ? ?               
disulf7  disulf ?    ? A CYS 370 SG  ? ? ? 1_555 A CYS 436 SG ? ? A CYS 378 A CYS 445 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf8  disulf ?    ? A CYS 377 SG  ? ? ? 1_555 A CYS 409 SG ? ? A CYS 385 A CYS 418 1_555 ? ? ? ? ? ? ? 2.020 ? ?               
disulf9  disulf ?    ? A CYS 492 SG  ? ? ? 1_555 B CYS 94  SG ? ? A CYS 501 B CYS 605 1_555 ? ? ? ? ? ? ? 2.023 ? ?               
disulf10 disulf ?    ? B CYS 87  SG  ? ? ? 1_555 B CYS 93  SG ? ? B CYS 598 B CYS 604 1_555 ? ? ? ? ? ? ? 2.025 ? ?               
disulf11 disulf ?    ? C CYS 22  SG  ? ? ? 1_555 C CYS 96  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf12 disulf ?    ? D CYS 20  SG  ? ? ? 1_555 D CYS 88  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.022 ? ?               
covale1  covale one  ? A ASN 89  ND2 ? ? ? 1_555 K NAG .   C1 ? ? A ASN 88  A NAG 601 1_555 ? ? ? ? ? ? ? 1.506 ? N-Glycosylation 
covale2  covale one  ? A ASN 134 ND2 ? ? ? 1_555 W NAG .   C1 ? ? A ASN 133 A NAG 613 1_555 ? ? ? ? ? ? ? 1.518 ? N-Glycosylation 
covale3  covale one  ? A ASN 138 ND2 ? ? ? 1_555 N NAG .   C1 ? ? A ASN 137 A NAG 604 1_555 ? ? ? ? ? ? ? 1.519 ? N-Glycosylation 
covale4  covale one  ? A ASN 149 ND2 ? ? ? 1_555 H NAG .   C1 ? ? A ASN 156 F NAG 1   1_555 ? ? ? ? ? ? ? 1.513 ? N-Glycosylation 
covale5  covale one  ? A ASN 153 ND2 ? ? ? 1_555 L NAG .   C1 ? ? A ASN 160 A NAG 602 1_555 ? ? ? ? ? ? ? 1.510 ? N-Glycosylation 
covale6  covale one  ? A ASN 190 ND2 ? ? ? 1_555 V NAG .   C1 ? ? A ASN 197 A NAG 612 1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale7  covale one  ? A ASN 227 ND2 ? ? ? 1_555 M NAG .   C1 ? ? A ASN 234 A NAG 603 1_555 ? ? ? ? ? ? ? 1.508 ? N-Glycosylation 
covale8  covale one  ? A ASN 255 ND2 ? ? ? 1_555 G NAG .   C1 ? ? A ASN 262 E NAG 1   1_555 ? ? ? ? ? ? ? 1.513 ? N-Glycosylation 
covale9  covale one  ? A ASN 269 ND2 ? ? ? 1_555 P NAG .   C1 ? ? A ASN 276 A NAG 606 1_555 ? ? ? ? ? ? ? 1.519 ? N-Glycosylation 
covale10 covale one  ? A ASN 288 ND2 ? ? ? 1_555 S NAG .   C1 ? ? A ASN 295 A NAG 609 1_555 ? ? ? ? ? ? ? 1.510 ? N-Glycosylation 
covale11 covale one  ? A ASN 294 ND2 ? ? ? 1_555 U NAG .   C1 ? ? A ASN 301 A NAG 611 1_555 ? ? ? ? ? ? ? 1.520 ? N-Glycosylation 
covale12 covale one  ? A ASN 324 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 332 D NAG 1   1_555 ? ? ? ? ? ? ? 1.503 ? N-Glycosylation 
covale13 covale one  ? A ASN 331 ND2 ? ? ? 1_555 R NAG .   C1 ? ? A ASN 339 A NAG 608 1_555 ? ? ? ? ? ? ? 1.528 ? N-Glycosylation 
covale14 covale one  ? A ASN 347 ND2 ? ? ? 1_555 O NAG .   C1 ? ? A ASN 355 A NAG 605 1_555 ? ? ? ? ? ? ? 1.516 ? N-Glycosylation 
covale15 covale one  ? A ASN 378 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 386 C NAG 1   1_555 ? ? ? ? ? ? ? 1.516 ? N-Glycosylation 
covale16 covale one  ? A ASN 384 ND2 ? ? ? 1_555 Q NAG .   C1 ? ? A ASN 392 A NAG 607 1_555 ? ? ? ? ? ? ? 1.521 ? N-Glycosylation 
covale17 covale one  ? A ASN 439 ND2 ? ? ? 1_555 T NAG .   C1 ? ? A ASN 448 A NAG 610 1_555 ? ? ? ? ? ? ? 1.523 ? N-Glycosylation 
covale18 covale one  ? B ASN 100 ND2 ? ? ? 1_555 J NAG .   C1 ? ? B ASN 611 I NAG 1   1_555 ? ? ? ? ? ? ? 1.429 ? N-Glycosylation 
covale19 covale one  ? B ASN 107 ND2 ? ? ? 1_555 I NAG .   C1 ? ? B ASN 618 G NAG 1   1_555 ? ? ? ? ? ? ? 1.517 ? N-Glycosylation 
covale20 covale one  ? B ASN 114 ND2 ? ? ? 1_555 X NAG .   C1 ? ? B ASN 625 B NAG 701 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale21 covale one  ? B ASN 126 ND2 ? ? ? 1_555 Y NAG .   C1 ? ? B ASN 637 B NAG 702 1_555 ? ? ? ? ? ? ? 1.433 ? N-Glycosylation 
covale22 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? C NAG 1   C NAG 2   1_555 ? ? ? ? ? ? ? 1.511 ? ?               
covale23 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.514 ? ?               
covale24 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.506 ? ?               
covale25 covale both ? G NAG .   O4  ? ? ? 1_555 G BMA .   C1 ? ? E NAG 2   E BMA 3   1_555 ? ? ? ? ? ? ? 1.509 ? ?               
covale26 covale both ? G BMA .   O3  ? ? ? 1_555 G MAN .   C1 ? ? E BMA 3   E MAN 4   1_555 ? ? ? ? ? ? ? 1.516 ? ?               
covale27 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.512 ? ?               
covale28 covale both ? I NAG .   O6  ? ? ? 1_555 I FUC .   C1 ? ? G NAG 1   G FUC 2   1_555 ? ? ? ? ? ? ? 1.512 ? ?               
covale29 covale both ? J NAG .   O6  ? ? ? 1_555 J FUC .   C1 ? ? I NAG 1   I FUC 2   1_555 ? ? ? ? ? ? ? 1.429 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3  ? 
AA2 ? 5  ? 
AA3 ? 2  ? 
AA4 ? 2  ? 
AA5 ? 5  ? 
AA6 ? 3  ? 
AA7 ? 12 ? 
AA8 ? 4  ? 
AA9 ? 7  ? 
AB1 ? 6  ? 
AB2 ? 3  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA5 3  4  ? anti-parallel 
AA5 4  5  ? anti-parallel 
AA6 1  2  ? parallel      
AA6 2  3  ? anti-parallel 
AA7 1  11 ? anti-parallel 
AA7 2  3  ? anti-parallel 
AA7 3  4  ? anti-parallel 
AA7 3  5  ? anti-parallel 
AA7 3  11 ? anti-parallel 
AA7 5  10 ? anti-parallel 
AA7 6  9  ? anti-parallel 
AA7 6  12 ? parallel      
AA7 7  8  ? anti-parallel 
AA7 8  10 ? anti-parallel 
AA7 11 12 ? anti-parallel 
AA8 1  2  ? anti-parallel 
AA8 2  3  ? anti-parallel 
AA8 3  4  ? anti-parallel 
AA9 1  7  ? parallel      
AA9 2  3  ? anti-parallel 
AA9 2  5  ? anti-parallel 
AA9 3  4  ? anti-parallel 
AA9 5  6  ? anti-parallel 
AA9 5  7  ? anti-parallel 
AB1 1  6  ? parallel      
AB1 2  3  ? anti-parallel 
AB1 2  4  ? anti-parallel 
AB1 4  5  ? anti-parallel 
AB1 4  6  ? anti-parallel 
AB2 1  2  ? anti-parallel 
AB2 2  3  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  LEU A 485 ? THR A 490 ? LEU A 494 THR A 499 
AA1 2  TRP A 36  ? TYR A 41  ? TRP A 35  TYR A 40  
AA1 3  ILE B 92  ? PRO B 98  ? ILE B 603 PRO B 609 
AA2 1  TRP A 46  ? ASP A 48  ? TRP A 45  ASP A 47  
AA2 2  TYR A 477 ? ILE A 482 ? TYR A 486 ILE A 491 
AA2 3  PHE A 216 ? CYS A 221 ? PHE A 223 CYS A 228 
AA2 4  VAL A 235 ? VAL A 238 ? VAL A 242 VAL A 245 
AA2 5  GLU A 84  ? ILE A 85  ? GLU A 83  ILE A 84  
AA3 1  PHE A 54  ? ALA A 56  ? PHE A 53  ALA A 55  
AA3 2  HIS A 209 ? CYS A 211 ? HIS A 216 CYS A 218 
AA4 1  GLU A 92  ? ASN A 95  ? GLU A 91  ASN A 94  
AA4 2  THR A 229 ? CYS A 232 ? THR A 236 CYS A 239 
AA5 1  ARG A 162 ? TYR A 170 ? ARG A 169 TYR A 177 
AA5 2  LEU A 147 ? THR A 155 ? LEU A 154 THR A 162 
AA5 3  LEU A 130 ? ASN A 134 ? LEU A 129 ASN A 133 
AA5 4  ASN A 183 ? LEU A 186 ? ASN A 190 LEU A 193 
AA5 5  ILE A 174 ? PRO A 176 ? ILE A 181 PRO A 183 
AA6 1  ILE A 194 ? GLN A 196 ? ILE A 201 GLN A 203 
AA6 2  ALA A 424 ? TYR A 426 ? ALA A 433 TYR A 435 
AA6 3  ILE A 414 ? ILE A 415 ? ILE A 423 ILE A 424 
AA7 1  LEU A 252 ? LEU A 254 ? LEU A 259 LEU A 261 
AA7 2  ILE A 264 ? SER A 267 ? ILE A 271 SER A 274 
AA7 3  ILE A 277 ? GLY A 303 ? ILE A 284 GLY A 312 
AA7 4  GLN A 306 ? ILE A 315 A GLN A 315 ILE A 323 
AA7 5  ALA A 321 ? SER A 326 ? ALA A 329 SER A 334 
AA7 6  ILE A 350 ? PHE A 353 ? ILE A 358 PHE A 361 
AA7 7  HIS A 366 ? CYS A 370 ? HIS A 374 CYS A 378 
AA7 8  GLU A 373 ? CYS A 377 ? GLU A 381 CYS A 385 
AA7 9  SER A 385 ? ILE A 388 ? SER A 393 ILE A 396 
AA7 10 SER A 404 ? LYS A 412 ? SER A 413 LYS A 421 
AA7 11 GLY A 432 ? ARG A 447 ? GLY A 441 ARG A 456 
AA7 12 GLU A 457 ? PRO A 461 ? GLU A 466 PRO A 470 
AA8 1  GLN C 3   ? GLU C 6   ? GLN H 3   GLU H 6   
AA8 2  SER C 17  ? SER C 25  ? SER H 17  SER H 25  
AA8 3  THR C 78  ? HIS C 84  A THR H 77  HIS H 82  
AA8 4  PHE C 68  ? ASP C 73  ? PHE H 67  ASP H 72  
AA9 1  LEU C 11  ? VAL C 12  ? LEU H 11  VAL H 12  
AA9 2  MET C 34  ? GLN C 39  ? MET H 34  GLN H 39  
AA9 3  LEU C 45  ? ILE C 51  ? LEU H 45  ILE H 51  
AA9 4  THR C 58  ? TYR C 60  ? THR H 57  TYR H 59  
AA9 5  ALA C 92  ? GLY C 99  ? ALA H 88  GLY H 95  
AA9 6  PHE C 112 H TRP C 115 ? PHE H 100 TRP H 103 
AA9 7  ALA C 119 ? VAL C 123 ? ALA H 107 VAL H 111 
AB1 1  SER D 9   ? GLY D 10  ? SER L 12  GLY L 13  
AB1 2  VAL D 33  ? GLN D 38  ? VAL L 33  GLN L 38  
AB1 3  LYS D 45  ? ILE D 48  ? LYS L 45  ILE L 48  
AB1 4  ALA D 84  ? TYR D 91  ? ALA L 84  TYR L 91  
AB1 5  TYR D 98  ? PHE D 100 ? TYR L 96  PHE L 98  
AB1 6  THR D 104 ? VAL D 108 ? THR L 102 VAL L 106 
AB2 1  VAL D 16  ? THR D 21  ? VAL L 19  THR L 24  
AB2 2  THR D 70  ? ILE D 75  ? THR L 70  ILE L 75  
AB2 3  PHE D 62  ? SER D 67  ? PHE L 62  SER L 67  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  O GLY A 486 ? O GLY A 495 N TYR A 40  ? N TYR A 39  
AA1 2  3  N VAL A 37  ? N VAL A 36  O VAL B 97  ? O VAL B 608 
AA2 1  2  N LYS A 47  ? N LYS A 46  O LYS A 481 ? O LYS A 490 
AA2 2  3  O LYS A 478 ? O LYS A 487 N LEU A 219 ? N LEU A 226 
AA2 3  4  N LYS A 220 ? N LYS A 227 O SER A 236 ? O SER A 243 
AA2 4  5  O THR A 237 ? O THR A 244 N ILE A 85  ? N ILE A 84  
AA3 1  2  N PHE A 54  ? N PHE A 53  O CYS A 211 ? O CYS A 218 
AA4 1  2  N PHE A 94  ? N PHE A 93  O GLY A 230 ? O GLY A 237 
AA5 1  2  O VAL A 165 ? O VAL A 172 N PHE A 152 ? N PHE A 159 
AA5 2  3  O ASN A 149 ? O ASN A 156 N THR A 133 ? N THR A 132 
AA5 3  4  N LEU A 130 ? N LEU A 129 O TYR A 184 ? O TYR A 191 
AA5 4  5  O ARG A 185 ? O ARG A 192 N VAL A 175 ? N VAL A 182 
AA6 1  2  N THR A 195 ? N THR A 202 O TYR A 426 ? O TYR A 435 
AA6 2  3  O MET A 425 ? O MET A 434 N ILE A 415 ? N ILE A 424 
AA7 1  11 N LEU A 253 ? N LEU A 260 O GLY A 442 ? O GLY A 451 
AA7 2  3  N ARG A 266 ? N ARG A 273 O LEU A 278 ? O LEU A 285 
AA7 3  4  N THR A 296 ? N THR A 303 O GLY A 312 ? O GLY A 321 
AA7 3  5  N THR A 290 ? N THR A 297 O HIS A 322 ? O HIS A 330 
AA7 3  11 N ILE A 277 ? N ILE A 284 O LEU A 445 ? O LEU A 454 
AA7 5  10 N VAL A 325 ? N VAL A 333 O ILE A 405 ? O ILE A 414 
AA7 6  9  N ILE A 351 ? N ILE A 359 O TRP A 387 ? O TRP A 395 
AA7 6  12 N ARG A 352 ? N ARG A 360 O PHE A 459 ? O PHE A 468 
AA7 7  8  N HIS A 366 ? N HIS A 374 O CYS A 377 ? O CYS A 385 
AA7 8  10 N TYR A 376 ? N TYR A 384 O ARG A 410 ? O ARG A 419 
AA7 11 12 N THR A 446 ? N THR A 455 O ARG A 460 ? O ARG A 469 
AA8 1  2  N VAL C 5   ? N VAL H 5   O ARG C 23  ? O ARG H 23  
AA8 2  3  N LEU C 20  ? N LEU H 20  O LEU C 81  ? O LEU H 80  
AA8 3  4  O GLN C 82  ? O GLN H 81  N THR C 69  ? N THR H 68  
AA9 1  7  N VAL C 12  ? N VAL H 12  O THR C 122 ? O THR H 110 
AA9 2  3  N ARG C 38  ? N ARG H 38  O GLU C 46  ? O GLU H 46  
AA9 2  5  N VAL C 37  ? N VAL H 37  O TYR C 95  ? O TYR H 91  
AA9 3  4  N LEU C 50  ? N LEU H 50  O PHE C 59  ? O PHE H 58  
AA9 5  6  N THR C 98  ? N THR H 94  O PHE C 114 ? O PHE H 102 
AA9 5  7  N TYR C 94  ? N TYR H 90  O ALA C 119 ? O ALA H 107 
AB1 1  6  N GLY D 10  ? N GLY L 13  O THR D 107 ? O THR L 105 
AB1 2  3  N TRP D 35  ? N TRP L 35  O MET D 47  ? O MET L 47  
AB1 2  4  N TYR D 36  ? N TYR L 36  O TYR D 87  ? O TYR L 87  
AB1 4  5  N ALA D 90  ? N ALA L 90  O ILE D 99  ? O ILE L 97  
AB1 4  6  N TYR D 86  ? N TYR L 86  O THR D 104 ? O THR L 102 
AB2 1  2  N CYS D 20  ? N CYS L 23  O ALA D 71  ? O ALA L 71  
AB2 2  3  O THR D 74  ? O THR L 74  N SER D 63  ? N SER L 63  
# 
_atom_sites.entry_id                    7T75 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASN A 1 34  ? 189.195 202.643 203.684 1.00 6.48   ? 33  ASN A N   1 
ATOM   2    C CA  . ASN A 1 34  ? 188.395 203.769 203.232 1.00 0.44   ? 33  ASN A CA  1 
ATOM   3    C C   . ASN A 1 34  ? 187.381 203.277 202.164 1.00 1.34   ? 33  ASN A C   1 
ATOM   4    O O   . ASN A 1 34  ? 186.226 202.996 202.518 1.00 4.93   ? 33  ASN A O   1 
ATOM   5    C CB  . ASN A 1 34  ? 189.325 204.952 202.791 1.00 11.48  ? 33  ASN A CB  1 
ATOM   6    C CG  . ASN A 1 34  ? 188.582 206.325 202.388 1.00 3.66   ? 33  ASN A CG  1 
ATOM   7    O OD1 . ASN A 1 34  ? 187.777 206.860 203.182 1.00 0.00   ? 33  ASN A OD1 1 
ATOM   8    N ND2 . ASN A 1 34  ? 188.881 206.867 201.173 1.00 8.68   ? 33  ASN A ND2 1 
ATOM   9    N N   . LEU A 1 35  ? 187.799 203.243 200.871 1.00 3.06   ? 34  LEU A N   1 
ATOM   10   C CA  . LEU A 1 35  ? 187.022 202.820 199.701 1.00 1.89   ? 34  LEU A CA  1 
ATOM   11   C C   . LEU A 1 35  ? 187.722 201.684 199.012 1.00 1.55   ? 34  LEU A C   1 
ATOM   12   O O   . LEU A 1 35  ? 188.950 201.619 199.015 1.00 2.94   ? 34  LEU A O   1 
ATOM   13   C CB  . LEU A 1 35  ? 186.825 203.986 198.739 1.00 1.55   ? 34  LEU A CB  1 
ATOM   14   C CG  . LEU A 1 35  ? 186.067 205.175 199.276 1.00 0.00   ? 34  LEU A CG  1 
ATOM   15   C CD1 . LEU A 1 35  ? 186.132 206.286 198.305 1.00 2.39   ? 34  LEU A CD1 1 
ATOM   16   C CD2 . LEU A 1 35  ? 184.652 204.808 199.494 1.00 1.59   ? 34  LEU A CD2 1 
ATOM   17   N N   . TRP A 1 36  ? 186.929 200.800 198.432 1.00 2.32   ? 35  TRP A N   1 
ATOM   18   C CA  . TRP A 1 36  ? 187.361 199.579 197.774 1.00 2.39   ? 35  TRP A CA  1 
ATOM   19   C C   . TRP A 1 36  ? 186.823 199.473 196.368 1.00 2.65   ? 35  TRP A C   1 
ATOM   20   O O   . TRP A 1 36  ? 185.778 200.037 196.051 1.00 3.67   ? 35  TRP A O   1 
ATOM   21   C CB  . TRP A 1 36  ? 186.878 198.410 198.611 1.00 3.73   ? 35  TRP A CB  1 
ATOM   22   C CG  . TRP A 1 36  ? 187.413 198.483 199.977 1.00 2.93   ? 35  TRP A CG  1 
ATOM   23   C CD1 . TRP A 1 36  ? 186.865 199.132 201.034 1.00 2.12   ? 35  TRP A CD1 1 
ATOM   24   C CD2 . TRP A 1 36  ? 188.613 197.926 200.443 1.00 2.81   ? 35  TRP A CD2 1 
ATOM   25   N NE1 . TRP A 1 36  ? 187.664 199.017 202.106 1.00 2.00   ? 35  TRP A NE1 1 
ATOM   26   C CE2 . TRP A 1 36  ? 188.739 198.288 201.762 1.00 2.57   ? 35  TRP A CE2 1 
ATOM   27   C CE3 . TRP A 1 36  ? 189.574 197.173 199.864 1.00 4.02   ? 35  TRP A CE3 1 
ATOM   28   C CZ2 . TRP A 1 36  ? 189.805 197.921 202.493 1.00 5.19   ? 35  TRP A CZ2 1 
ATOM   29   C CZ3 . TRP A 1 36  ? 190.642 196.801 200.598 1.00 4.28   ? 35  TRP A CZ3 1 
ATOM   30   C CH2 . TRP A 1 36  ? 190.760 197.164 201.873 1.00 4.88   ? 35  TRP A CH2 1 
ATOM   31   N N   . VAL A 1 37  ? 187.557 198.833 195.473 1.00 4.19   ? 36  VAL A N   1 
ATOM   32   C CA  . VAL A 1 37  ? 187.104 198.576 194.079 1.00 3.78   ? 36  VAL A CA  1 
ATOM   33   C C   . VAL A 1 37  ? 185.914 197.608 194.114 1.00 5.10   ? 36  VAL A C   1 
ATOM   34   O O   . VAL A 1 37  ? 186.040 196.554 194.722 1.00 6.67   ? 36  VAL A O   1 
ATOM   35   C CB  . VAL A 1 37  ? 188.250 198.032 193.202 1.00 4.01   ? 36  VAL A CB  1 
ATOM   36   C CG1 . VAL A 1 37  ? 187.799 197.712 191.790 1.00 4.15   ? 36  VAL A CG1 1 
ATOM   37   C CG2 . VAL A 1 37  ? 189.460 198.944 193.202 1.00 4.28   ? 36  VAL A CG2 1 
ATOM   38   N N   . THR A 1 38  ? 184.781 197.973 193.524 1.00 5.30   ? 37  THR A N   1 
ATOM   39   C CA  . THR A 1 38  ? 183.645 197.078 193.358 1.00 4.11   ? 37  THR A CA  1 
ATOM   40   C C   . THR A 1 38  ? 183.369 196.931 191.885 1.00 4.49   ? 37  THR A C   1 
ATOM   41   O O   . THR A 1 38  ? 183.362 197.908 191.130 1.00 6.10   ? 37  THR A O   1 
ATOM   42   C CB  . THR A 1 38  ? 182.403 197.550 194.129 1.00 3.58   ? 37  THR A CB  1 
ATOM   43   O OG1 . THR A 1 38  ? 182.720 197.573 195.511 1.00 5.22   ? 37  THR A OG1 1 
ATOM   44   C CG2 . THR A 1 38  ? 181.212 196.604 193.930 1.00 3.52   ? 37  THR A CG2 1 
ATOM   45   N N   . VAL A 1 39  ? 183.209 195.692 191.471 1.00 5.18   ? 38  VAL A N   1 
ATOM   46   C CA  . VAL A 1 39  ? 182.987 195.341 190.093 1.00 4.63   ? 38  VAL A CA  1 
ATOM   47   C C   . VAL A 1 39  ? 181.503 195.208 189.803 1.00 4.61   ? 38  VAL A C   1 
ATOM   48   O O   . VAL A 1 39  ? 180.773 194.531 190.527 1.00 4.99   ? 38  VAL A O   1 
ATOM   49   C CB  . VAL A 1 39  ? 183.712 194.018 189.784 1.00 3.71   ? 38  VAL A CB  1 
ATOM   50   C CG1 . VAL A 1 39  ? 183.474 193.605 188.367 1.00 5.97   ? 38  VAL A CG1 1 
ATOM   51   C CG2 . VAL A 1 39  ? 185.192 194.139 190.077 1.00 3.28   ? 38  VAL A CG2 1 
ATOM   52   N N   . TYR A 1 40  ? 181.053 195.862 188.743 1.00 6.02   ? 39  TYR A N   1 
ATOM   53   C CA  . TYR A 1 40  ? 179.667 195.810 188.318 1.00 4.78   ? 39  TYR A CA  1 
ATOM   54   C C   . TYR A 1 40  ? 179.545 195.298 186.893 1.00 5.24   ? 39  TYR A C   1 
ATOM   55   O O   . TYR A 1 40  ? 180.269 195.738 185.997 1.00 6.85   ? 39  TYR A O   1 
ATOM   56   C CB  . TYR A 1 40  ? 179.044 197.199 188.391 1.00 4.03   ? 39  TYR A CB  1 
ATOM   57   C CG  . TYR A 1 40  ? 178.906 197.755 189.763 1.00 3.08   ? 39  TYR A CG  1 
ATOM   58   C CD1 . TYR A 1 40  ? 179.939 198.413 190.370 1.00 3.38   ? 39  TYR A CD1 1 
ATOM   59   C CD2 . TYR A 1 40  ? 177.729 197.614 190.403 1.00 2.34   ? 39  TYR A CD2 1 
ATOM   60   C CE1 . TYR A 1 40  ? 179.767 198.910 191.621 1.00 3.01   ? 39  TYR A CE1 1 
ATOM   61   C CE2 . TYR A 1 40  ? 177.555 198.105 191.641 1.00 1.88   ? 39  TYR A CE2 1 
ATOM   62   C CZ  . TYR A 1 40  ? 178.554 198.745 192.251 1.00 1.91   ? 39  TYR A CZ  1 
ATOM   63   O OH  . TYR A 1 40  ? 178.355 199.231 193.502 1.00 3.14   ? 39  TYR A OH  1 
ATOM   64   N N   . TYR A 1 41  ? 178.595 194.408 186.655 1.00 5.85   ? 40  TYR A N   1 
ATOM   65   C CA  . TYR A 1 41  ? 178.372 193.912 185.310 1.00 5.96   ? 40  TYR A CA  1 
ATOM   66   C C   . TYR A 1 41  ? 176.931 194.147 184.896 1.00 6.00   ? 40  TYR A C   1 
ATOM   67   O O   . TYR A 1 41  ? 176.018 193.771 185.612 1.00 6.54   ? 40  TYR A O   1 
ATOM   68   C CB  . TYR A 1 41  ? 178.749 192.450 185.240 1.00 6.02   ? 40  TYR A CB  1 
ATOM   69   C CG  . TYR A 1 41  ? 178.683 191.852 183.890 1.00 6.04   ? 40  TYR A CG  1 
ATOM   70   C CD1 . TYR A 1 41  ? 179.653 192.159 182.993 1.00 6.55   ? 40  TYR A CD1 1 
ATOM   71   C CD2 . TYR A 1 41  ? 177.702 190.980 183.554 1.00 7.34   ? 40  TYR A CD2 1 
ATOM   72   C CE1 . TYR A 1 41  ? 179.662 191.601 181.771 1.00 6.82   ? 40  TYR A CE1 1 
ATOM   73   C CE2 . TYR A 1 41  ? 177.700 190.411 182.324 1.00 7.49   ? 40  TYR A CE2 1 
ATOM   74   C CZ  . TYR A 1 41  ? 178.680 190.719 181.437 1.00 7.69   ? 40  TYR A CZ  1 
ATOM   75   O OH  . TYR A 1 41  ? 178.702 190.100 180.225 1.00 10.46  ? 40  TYR A OH  1 
ATOM   76   N N   . GLY A 1 42  ? 176.732 194.745 183.726 1.00 6.20   ? 41  GLY A N   1 
ATOM   77   C CA  . GLY A 1 42  ? 175.411 195.103 183.227 1.00 6.63   ? 41  GLY A CA  1 
ATOM   78   C C   . GLY A 1 42  ? 175.236 196.620 183.249 1.00 6.06   ? 41  GLY A C   1 
ATOM   79   O O   . GLY A 1 42  ? 174.126 197.140 183.332 1.00 7.94   ? 41  GLY A O   1 
ATOM   80   N N   . VAL A 1 43  ? 176.347 197.322 183.243 1.00 7.61   ? 42  VAL A N   1 
ATOM   81   C CA  . VAL A 1 43  ? 176.429 198.766 183.264 1.00 6.51   ? 42  VAL A CA  1 
ATOM   82   C C   . VAL A 1 43  ? 175.985 199.398 181.924 1.00 6.60   ? 42  VAL A C   1 
ATOM   83   O O   . VAL A 1 43  ? 176.454 198.981 180.871 1.00 7.62   ? 42  VAL A O   1 
ATOM   84   C CB  . VAL A 1 43  ? 177.888 199.110 183.598 1.00 5.42   ? 42  VAL A CB  1 
ATOM   85   C CG1 . VAL A 1 43  ? 178.117 200.496 183.507 1.00 5.56   ? 42  VAL A CG1 1 
ATOM   86   C CG2 . VAL A 1 43  ? 178.196 198.639 185.004 1.00 5.56   ? 42  VAL A CG2 1 
ATOM   87   N N   . PRO A 1 44  ? 175.089 200.410 181.900 1.00 7.17   ? 43  PRO A N   1 
ATOM   88   C CA  . PRO A 1 44  ? 174.578 201.057 180.697 1.00 6.26   ? 43  PRO A CA  1 
ATOM   89   C C   . PRO A 1 44  ? 175.549 202.046 180.065 1.00 6.57   ? 43  PRO A C   1 
ATOM   90   O O   . PRO A 1 44  ? 175.319 203.250 180.067 1.00 7.57   ? 43  PRO A O   1 
ATOM   91   C CB  . PRO A 1 44  ? 173.330 201.752 181.213 1.00 5.87   ? 43  PRO A CB  1 
ATOM   92   C CG  . PRO A 1 44  ? 173.654 202.103 182.611 1.00 5.01   ? 43  PRO A CG  1 
ATOM   93   C CD  . PRO A 1 44  ? 174.494 200.939 183.131 1.00 5.91   ? 43  PRO A CD  1 
ATOM   94   N N   . VAL A 1 45  ? 176.640 201.506 179.561 1.00 6.82   ? 44  VAL A N   1 
ATOM   95   C CA  . VAL A 1 45  ? 177.732 202.223 178.923 1.00 6.04   ? 44  VAL A CA  1 
ATOM   96   C C   . VAL A 1 45  ? 178.023 201.679 177.549 1.00 6.39   ? 44  VAL A C   1 
ATOM   97   O O   . VAL A 1 45  ? 177.877 200.485 177.314 1.00 7.36   ? 44  VAL A O   1 
ATOM   98   C CB  . VAL A 1 45  ? 178.988 202.187 179.804 1.00 5.24   ? 44  VAL A CB  1 
ATOM   99   C CG1 . VAL A 1 45  ? 180.217 202.747 179.104 1.00 7.18   ? 44  VAL A CG1 1 
ATOM   100  C CG2 . VAL A 1 45  ? 178.733 203.047 180.969 1.00 5.98   ? 44  VAL A CG2 1 
ATOM   101  N N   . TRP A 1 46  ? 178.378 202.563 176.631 1.00 7.16   ? 45  TRP A N   1 
ATOM   102  C CA  . TRP A 1 46  ? 178.701 202.180 175.278 1.00 6.35   ? 45  TRP A CA  1 
ATOM   103  C C   . TRP A 1 46  ? 179.787 203.036 174.674 1.00 7.06   ? 45  TRP A C   1 
ATOM   104  O O   . TRP A 1 46  ? 180.082 204.128 175.159 1.00 9.22   ? 45  TRP A O   1 
ATOM   105  C CB  . TRP A 1 46  ? 177.495 202.304 174.370 1.00 6.86   ? 45  TRP A CB  1 
ATOM   106  C CG  . TRP A 1 46  ? 176.919 203.670 174.297 1.00 6.80   ? 45  TRP A CG  1 
ATOM   107  C CD1 . TRP A 1 46  ? 177.316 204.669 173.493 1.00 6.64   ? 45  TRP A CD1 1 
ATOM   108  C CD2 . TRP A 1 46  ? 175.771 204.156 174.974 1.00 6.19   ? 45  TRP A CD2 1 
ATOM   109  N NE1 . TRP A 1 46  ? 176.526 205.740 173.654 1.00 6.20   ? 45  TRP A NE1 1 
ATOM   110  C CE2 . TRP A 1 46  ? 175.570 205.444 174.547 1.00 5.97   ? 45  TRP A CE2 1 
ATOM   111  C CE3 . TRP A 1 46  ? 174.905 203.609 175.881 1.00 6.67   ? 45  TRP A CE3 1 
ATOM   112  C CZ2 . TRP A 1 46  ? 174.539 206.196 174.997 1.00 6.71   ? 45  TRP A CZ2 1 
ATOM   113  C CZ3 . TRP A 1 46  ? 173.871 204.362 176.327 1.00 6.09   ? 45  TRP A CZ3 1 
ATOM   114  C CH2 . TRP A 1 46  ? 173.686 205.619 175.899 1.00 6.24   ? 45  TRP A CH2 1 
ATOM   115  N N   . LYS A 1 47  ? 180.381 202.525 173.603 1.00 7.98   ? 46  LYS A N   1 
ATOM   116  C CA  . LYS A 1 47  ? 181.409 203.215 172.833 1.00 9.06   ? 46  LYS A CA  1 
ATOM   117  C C   . LYS A 1 47  ? 181.110 203.140 171.351 1.00 8.79   ? 46  LYS A C   1 
ATOM   118  O O   . LYS A 1 47  ? 180.497 202.192 170.887 1.00 11.56  ? 46  LYS A O   1 
ATOM   119  C CB  . LYS A 1 47  ? 182.774 202.618 173.127 1.00 12.33  ? 46  LYS A CB  1 
ATOM   120  C CG  . LYS A 1 47  ? 183.179 202.797 174.562 1.00 18.86  ? 46  LYS A CG  1 
ATOM   121  C CD  . LYS A 1 47  ? 184.555 202.259 174.871 1.00 21.52  ? 46  LYS A CD  1 
ATOM   122  C CE  . LYS A 1 47  ? 184.801 202.287 176.387 1.00 21.90  ? 46  LYS A CE  1 
ATOM   123  N NZ  . LYS A 1 47  ? 184.817 203.661 176.936 1.00 28.61  ? 46  LYS A NZ  1 
ATOM   124  N N   . ASP A 1 48  ? 181.553 204.110 170.580 1.00 11.54  ? 47  ASP A N   1 
ATOM   125  C CA  . ASP A 1 48  ? 181.296 204.065 169.143 1.00 11.18  ? 47  ASP A CA  1 
ATOM   126  C C   . ASP A 1 48  ? 181.913 202.838 168.515 1.00 11.86  ? 47  ASP A C   1 
ATOM   127  O O   . ASP A 1 48  ? 183.041 202.473 168.852 1.00 13.24  ? 47  ASP A O   1 
ATOM   128  C CB  . ASP A 1 48  ? 181.859 205.295 168.479 1.00 13.88  ? 47  ASP A CB  1 
ATOM   129  C CG  . ASP A 1 48  ? 181.136 206.506 168.930 1.00 20.25  ? 47  ASP A CG  1 
ATOM   130  O OD1 . ASP A 1 48  ? 180.191 206.370 169.672 1.00 19.07  ? 47  ASP A OD1 1 
ATOM   131  O OD2 . ASP A 1 48  ? 181.442 207.584 168.504 1.00 21.35  ? 47  ASP A OD2 1 
ATOM   132  N N   . ALA A 1 49  ? 181.203 202.197 167.588 1.00 12.19  ? 48  ALA A N   1 
ATOM   133  C CA  . ALA A 1 49  ? 181.768 201.005 166.984 1.00 11.65  ? 48  ALA A CA  1 
ATOM   134  C C   . ALA A 1 49  ? 181.230 200.703 165.610 1.00 14.01  ? 48  ALA A C   1 
ATOM   135  O O   . ALA A 1 49  ? 180.148 201.137 165.244 1.00 13.94  ? 48  ALA A O   1 
ATOM   136  C CB  . ALA A 1 49  ? 181.494 199.830 167.870 1.00 11.51  ? 48  ALA A CB  1 
ATOM   137  N N   . GLU A 1 50  ? 181.998 199.940 164.849 1.00 17.88  ? 49  GLU A N   1 
ATOM   138  C CA  . GLU A 1 50  ? 181.551 199.468 163.554 1.00 18.51  ? 49  GLU A CA  1 
ATOM   139  C C   . GLU A 1 50  ? 181.295 197.983 163.634 1.00 17.23  ? 49  GLU A C   1 
ATOM   140  O O   . GLU A 1 50  ? 182.018 197.257 164.314 1.00 17.11  ? 49  GLU A O   1 
ATOM   141  C CB  . GLU A 1 50  ? 182.593 199.762 162.482 1.00 21.26  ? 49  GLU A CB  1 
ATOM   142  C CG  . GLU A 1 50  ? 182.833 201.234 162.233 1.00 24.18  ? 49  GLU A CG  1 
ATOM   143  C CD  . GLU A 1 50  ? 183.851 201.485 161.166 1.00 28.83  ? 49  GLU A CD  1 
ATOM   144  O OE1 . GLU A 1 50  ? 184.455 200.540 160.723 1.00 28.86  ? 49  GLU A OE1 1 
ATOM   145  O OE2 . GLU A 1 50  ? 184.022 202.619 160.789 1.00 30.42  ? 49  GLU A OE2 1 
ATOM   146  N N   . THR A 1 51  ? 180.267 197.531 162.948 1.00 17.44  ? 50  THR A N   1 
ATOM   147  C CA  . THR A 1 51  ? 179.964 196.119 162.889 1.00 17.84  ? 50  THR A CA  1 
ATOM   148  C C   . THR A 1 51  ? 179.176 195.831 161.637 1.00 20.58  ? 50  THR A C   1 
ATOM   149  O O   . THR A 1 51  ? 179.025 196.698 160.780 1.00 21.37  ? 50  THR A O   1 
ATOM   150  C CB  . THR A 1 51  ? 179.194 195.633 164.127 1.00 16.34  ? 50  THR A CB  1 
ATOM   151  O OG1 . THR A 1 51  ? 179.154 194.201 164.109 1.00 17.55  ? 50  THR A OG1 1 
ATOM   152  C CG2 . THR A 1 51  ? 177.764 196.193 164.162 1.00 15.05  ? 50  THR A CG2 1 
ATOM   153  N N   . THR A 1 52  ? 178.682 194.619 161.539 1.00 21.07  ? 51  THR A N   1 
ATOM   154  C CA  . THR A 1 52  ? 177.870 194.196 160.424 1.00 20.28  ? 51  THR A CA  1 
ATOM   155  C C   . THR A 1 52  ? 176.423 194.193 160.844 1.00 19.89  ? 51  THR A C   1 
ATOM   156  O O   . THR A 1 52  ? 176.051 193.485 161.774 1.00 21.58  ? 51  THR A O   1 
ATOM   157  C CB  . THR A 1 52  ? 178.281 192.782 159.986 1.00 24.61  ? 51  THR A CB  1 
ATOM   158  O OG1 . THR A 1 52  ? 179.638 192.799 159.536 1.00 25.86  ? 51  THR A OG1 1 
ATOM   159  C CG2 . THR A 1 52  ? 177.392 192.256 158.915 1.00 27.95  ? 51  THR A CG2 1 
ATOM   160  N N   . LEU A 1 53  ? 175.593 194.940 160.146 1.00 20.23  ? 52  LEU A N   1 
ATOM   161  C CA  . LEU A 1 53  ? 174.179 194.984 160.473 1.00 20.55  ? 52  LEU A CA  1 
ATOM   162  C C   . LEU A 1 53  ? 173.460 193.991 159.596 1.00 22.26  ? 52  LEU A C   1 
ATOM   163  O O   . LEU A 1 53  ? 173.890 193.712 158.478 1.00 23.44  ? 52  LEU A O   1 
ATOM   164  C CB  . LEU A 1 53  ? 173.618 196.388 160.290 1.00 21.60  ? 52  LEU A CB  1 
ATOM   165  C CG  . LEU A 1 53  ? 174.258 197.500 161.127 1.00 18.46  ? 52  LEU A CG  1 
ATOM   166  C CD1 . LEU A 1 53  ? 173.647 198.777 160.740 1.00 16.22  ? 52  LEU A CD1 1 
ATOM   167  C CD2 . LEU A 1 53  ? 174.032 197.271 162.606 1.00 17.18  ? 52  LEU A CD2 1 
ATOM   168  N N   . PHE A 1 54  ? 172.333 193.492 160.049 1.00 23.76  ? 53  PHE A N   1 
ATOM   169  C CA  . PHE A 1 54  ? 171.613 192.530 159.234 1.00 26.60  ? 53  PHE A CA  1 
ATOM   170  C C   . PHE A 1 54  ? 170.275 193.097 158.769 1.00 24.96  ? 53  PHE A C   1 
ATOM   171  O O   . PHE A 1 54  ? 169.802 194.090 159.319 1.00 27.86  ? 53  PHE A O   1 
ATOM   172  C CB  . PHE A 1 54  ? 171.472 191.195 159.978 1.00 27.54  ? 53  PHE A CB  1 
ATOM   173  C CG  . PHE A 1 54  ? 170.659 191.189 161.212 1.00 24.76  ? 53  PHE A CG  1 
ATOM   174  C CD1 . PHE A 1 54  ? 169.314 190.917 161.144 1.00 26.43  ? 53  PHE A CD1 1 
ATOM   175  C CD2 . PHE A 1 54  ? 171.228 191.426 162.441 1.00 21.06  ? 53  PHE A CD2 1 
ATOM   176  C CE1 . PHE A 1 54  ? 168.548 190.873 162.266 1.00 25.02  ? 53  PHE A CE1 1 
ATOM   177  C CE2 . PHE A 1 54  ? 170.465 191.389 163.573 1.00 20.74  ? 53  PHE A CE2 1 
ATOM   178  C CZ  . PHE A 1 54  ? 169.124 191.109 163.489 1.00 21.92  ? 53  PHE A CZ  1 
ATOM   179  N N   . CYS A 1 55  ? 169.704 192.492 157.702 1.00 29.36  ? 54  CYS A N   1 
ATOM   180  C CA  . CYS A 1 55  ? 168.437 192.878 157.086 1.00 27.92  ? 54  CYS A CA  1 
ATOM   181  C C   . CYS A 1 55  ? 167.236 192.482 157.930 1.00 30.88  ? 54  CYS A C   1 
ATOM   182  O O   . CYS A 1 55  ? 167.205 191.437 158.572 1.00 34.50  ? 54  CYS A O   1 
ATOM   183  C CB  . CYS A 1 55  ? 168.212 192.154 155.741 1.00 23.72  ? 54  CYS A CB  1 
ATOM   184  S SG  . CYS A 1 55  ? 169.349 192.465 154.419 1.00 62.82  ? 54  CYS A SG  1 
ATOM   185  N N   . ALA A 1 56  ? 166.204 193.254 157.773 1.00 32.39  ? 55  ALA A N   1 
ATOM   186  C CA  . ALA A 1 56  ? 164.914 192.808 158.198 1.00 36.30  ? 55  ALA A CA  1 
ATOM   187  C C   . ALA A 1 56  ? 163.900 193.416 157.235 1.00 37.39  ? 55  ALA A C   1 
ATOM   188  O O   . ALA A 1 56  ? 163.808 194.636 157.107 1.00 37.77  ? 55  ALA A O   1 
ATOM   189  C CB  . ALA A 1 56  ? 164.688 193.164 159.640 1.00 35.50  ? 55  ALA A CB  1 
ATOM   190  N N   . SER A 1 57  ? 163.120 192.583 156.567 1.00 42.97  ? 56  SER A N   1 
ATOM   191  C CA  . SER A 1 57  ? 162.118 193.090 155.620 1.00 43.76  ? 56  SER A CA  1 
ATOM   192  C C   . SER A 1 57  ? 160.832 192.237 155.567 1.00 47.13  ? 56  SER A C   1 
ATOM   193  O O   . SER A 1 57  ? 160.761 191.158 156.163 1.00 48.16  ? 56  SER A O   1 
ATOM   194  C CB  . SER A 1 57  ? 162.751 193.178 154.237 1.00 41.63  ? 56  SER A CB  1 
ATOM   195  O OG  . SER A 1 57  ? 163.037 191.903 153.732 1.00 45.17  ? 56  SER A OG  1 
ATOM   196  N N   . ASP A 1 58  ? 159.765 192.765 154.909 1.00 51.59  ? 57  ASP A N   1 
ATOM   197  C CA  . ASP A 1 58  ? 158.466 192.087 154.714 1.00 55.91  ? 57  ASP A CA  1 
ATOM   198  C C   . ASP A 1 58  ? 158.422 191.508 153.302 1.00 55.28  ? 57  ASP A C   1 
ATOM   199  O O   . ASP A 1 58  ? 157.569 190.680 152.965 1.00 60.32  ? 57  ASP A O   1 
ATOM   200  C CB  . ASP A 1 58  ? 157.257 193.052 154.957 1.00 61.13  ? 57  ASP A CB  1 
ATOM   201  C CG  . ASP A 1 58  ? 156.984 193.430 156.450 1.00 57.40  ? 57  ASP A CG  1 
ATOM   202  O OD1 . ASP A 1 58  ? 157.031 192.558 157.283 1.00 55.68  ? 57  ASP A OD1 1 
ATOM   203  O OD2 . ASP A 1 58  ? 156.750 194.574 156.700 1.00 61.15  ? 57  ASP A OD2 1 
ATOM   204  N N   . GLN A 1 83  ? 160.417 198.266 171.235 1.00 33.03  ? 82  GLN A N   1 
ATOM   205  C CA  . GLN A 1 83  ? 161.237 198.498 170.045 1.00 33.32  ? 82  GLN A CA  1 
ATOM   206  C C   . GLN A 1 83  ? 162.070 199.800 170.126 1.00 25.97  ? 82  GLN A C   1 
ATOM   207  O O   . GLN A 1 83  ? 163.156 199.868 169.519 1.00 24.69  ? 82  GLN A O   1 
ATOM   208  C CB  . GLN A 1 83  ? 160.362 198.494 168.747 1.00 38.07  ? 82  GLN A CB  1 
ATOM   209  C CG  . GLN A 1 83  ? 159.691 197.097 168.369 1.00 43.26  ? 82  GLN A CG  1 
ATOM   210  C CD  . GLN A 1 83  ? 158.834 197.119 167.026 1.00 48.32  ? 82  GLN A CD  1 
ATOM   211  O OE1 . GLN A 1 83  ? 158.301 198.169 166.614 1.00 48.57  ? 82  GLN A OE1 1 
ATOM   212  N NE2 . GLN A 1 83  ? 158.713 195.901 166.354 1.00 54.47  ? 82  GLN A NE2 1 
ATOM   213  N N   . GLU A 1 84  ? 161.553 200.844 170.836 1.00 21.97  ? 83  GLU A N   1 
ATOM   214  C CA  . GLU A 1 84  ? 162.208 202.148 171.037 1.00 18.43  ? 83  GLU A CA  1 
ATOM   215  C C   . GLU A 1 84  ? 162.142 202.593 172.493 1.00 17.41  ? 83  GLU A C   1 
ATOM   216  O O   . GLU A 1 84  ? 161.072 202.637 173.100 1.00 18.47  ? 83  GLU A O   1 
ATOM   217  C CB  . GLU A 1 84  ? 161.590 203.211 170.141 1.00 20.78  ? 83  GLU A CB  1 
ATOM   218  C CG  . GLU A 1 84  ? 162.255 204.555 170.271 1.00 19.44  ? 83  GLU A CG  1 
ATOM   219  C CD  . GLU A 1 84  ? 161.741 205.566 169.336 1.00 22.33  ? 83  GLU A CD  1 
ATOM   220  O OE1 . GLU A 1 84  ? 160.891 205.270 168.544 1.00 24.73  ? 83  GLU A OE1 1 
ATOM   221  O OE2 . GLU A 1 84  ? 162.254 206.656 169.354 1.00 24.39  ? 83  GLU A OE2 1 
ATOM   222  N N   . ILE A 1 85  ? 163.304 202.950 173.037 1.00 15.31  ? 84  ILE A N   1 
ATOM   223  C CA  . ILE A 1 85  ? 163.465 203.383 174.422 1.00 13.80  ? 84  ILE A CA  1 
ATOM   224  C C   . ILE A 1 85  ? 163.989 204.804 174.486 1.00 12.43  ? 84  ILE A C   1 
ATOM   225  O O   . ILE A 1 85  ? 165.014 205.117 173.905 1.00 14.42  ? 84  ILE A O   1 
ATOM   226  C CB  . ILE A 1 85  ? 164.420 202.428 175.131 1.00 12.90  ? 84  ILE A CB  1 
ATOM   227  C CG1 . ILE A 1 85  ? 163.818 201.029 175.067 1.00 13.33  ? 84  ILE A CG1 1 
ATOM   228  C CG2 . ILE A 1 85  ? 164.673 202.881 176.599 1.00 11.56  ? 84  ILE A CG2 1 
ATOM   229  C CD1 . ILE A 1 85  ? 164.742 199.991 175.421 1.00 16.25  ? 84  ILE A CD1 1 
ATOM   230  N N   . HIS A 1 86  ? 163.329 205.679 175.218 1.00 13.18  ? 85  HIS A N   1 
ATOM   231  C CA  . HIS A 1 86  ? 163.726 207.084 175.230 1.00 12.61  ? 85  HIS A CA  1 
ATOM   232  C C   . HIS A 1 86  ? 165.086 207.522 175.827 1.00 13.70  ? 85  HIS A C   1 
ATOM   233  O O   . HIS A 1 86  ? 165.560 208.580 175.466 1.00 17.60  ? 85  HIS A O   1 
ATOM   234  C CB  . HIS A 1 86  ? 162.619 207.929 175.839 1.00 15.41  ? 85  HIS A CB  1 
ATOM   235  C CG  . HIS A 1 86  ? 162.876 209.380 175.694 1.00 16.79  ? 85  HIS A CG  1 
ATOM   236  N ND1 . HIS A 1 86  ? 162.936 210.029 174.465 1.00 16.94  ? 85  HIS A ND1 1 
ATOM   237  C CD2 . HIS A 1 86  ? 163.083 210.311 176.616 1.00 18.21  ? 85  HIS A CD2 1 
ATOM   238  C CE1 . HIS A 1 86  ? 163.224 211.300 174.678 1.00 18.61  ? 85  HIS A CE1 1 
ATOM   239  N NE2 . HIS A 1 86  ? 163.306 211.490 175.971 1.00 19.89  ? 85  HIS A NE2 1 
ATOM   240  N N   . LEU A 1 87  ? 165.716 206.820 176.766 1.00 13.14  ? 86  LEU A N   1 
ATOM   241  C CA  . LEU A 1 87  ? 167.015 207.360 177.260 1.00 12.15  ? 86  LEU A CA  1 
ATOM   242  C C   . LEU A 1 87  ? 166.922 208.850 177.689 1.00 12.39  ? 86  LEU A C   1 
ATOM   243  O O   . LEU A 1 87  ? 167.595 209.730 177.142 1.00 13.40  ? 86  LEU A O   1 
ATOM   244  C CB  . LEU A 1 87  ? 168.098 207.205 176.170 1.00 10.20  ? 86  LEU A CB  1 
ATOM   245  C CG  . LEU A 1 87  ? 168.885 205.877 176.078 1.00 9.04   ? 86  LEU A CG  1 
ATOM   246  C CD1 . LEU A 1 87  ? 167.967 204.723 175.819 1.00 10.01  ? 86  LEU A CD1 1 
ATOM   247  C CD2 . LEU A 1 87  ? 169.898 206.010 174.950 1.00 8.42   ? 86  LEU A CD2 1 
ATOM   248  N N   . GLU A 1 88  ? 166.140 209.108 178.733 1.00 15.91  ? 87  GLU A N   1 
ATOM   249  C CA  . GLU A 1 88  ? 165.752 210.457 179.164 1.00 16.14  ? 87  GLU A CA  1 
ATOM   250  C C   . GLU A 1 88  ? 166.792 211.575 179.292 1.00 17.84  ? 87  GLU A C   1 
ATOM   251  O O   . GLU A 1 88  ? 166.468 212.694 178.889 1.00 21.94  ? 87  GLU A O   1 
ATOM   252  C CB  . GLU A 1 88  ? 165.039 210.324 180.512 1.00 19.07  ? 87  GLU A CB  1 
ATOM   253  C CG  . GLU A 1 88  ? 164.476 211.609 181.125 1.00 22.41  ? 87  GLU A CG  1 
ATOM   254  C CD  . GLU A 1 88  ? 163.314 212.162 180.406 1.00 29.13  ? 87  GLU A CD  1 
ATOM   255  O OE1 . GLU A 1 88  ? 162.595 211.397 179.811 1.00 32.10  ? 87  GLU A OE1 1 
ATOM   256  O OE2 . GLU A 1 88  ? 163.111 213.348 180.479 1.00 31.37  ? 87  GLU A OE2 1 
ATOM   257  N N   . ASN A 1 89  ? 168.009 211.334 179.827 1.00 13.30  ? 88  ASN A N   1 
ATOM   258  C CA  . ASN A 1 89  ? 169.020 212.394 180.018 1.00 12.03  ? 88  ASN A CA  1 
ATOM   259  C C   . ASN A 1 89  ? 170.324 212.129 179.245 1.00 11.80  ? 88  ASN A C   1 
ATOM   260  O O   . ASN A 1 89  ? 171.403 212.528 179.694 1.00 13.12  ? 88  ASN A O   1 
ATOM   261  C CB  . ASN A 1 89  ? 169.297 212.624 181.515 1.00 14.32  ? 88  ASN A CB  1 
ATOM   262  C CG  . ASN A 1 89  ? 168.105 213.212 182.302 1.00 16.22  ? 88  ASN A CG  1 
ATOM   263  O OD1 . ASN A 1 89  ? 167.374 214.080 181.792 1.00 18.44  ? 88  ASN A OD1 1 
ATOM   264  N ND2 . ASN A 1 89  ? 167.928 212.745 183.531 1.00 18.21  ? 88  ASN A ND2 1 
ATOM   265  N N   . VAL A 1 90  ? 170.250 211.441 178.081 1.00 12.60  ? 89  VAL A N   1 
ATOM   266  C CA  . VAL A 1 90  ? 171.412 211.146 177.243 1.00 10.53  ? 89  VAL A CA  1 
ATOM   267  C C   . VAL A 1 90  ? 171.577 212.152 176.127 1.00 12.30  ? 89  VAL A C   1 
ATOM   268  O O   . VAL A 1 90  ? 170.671 212.383 175.340 1.00 14.26  ? 89  VAL A O   1 
ATOM   269  C CB  . VAL A 1 90  ? 171.292 209.742 176.644 1.00 9.11   ? 89  VAL A CB  1 
ATOM   270  C CG1 . VAL A 1 90  ? 172.461 209.438 175.698 1.00 9.91   ? 89  VAL A CG1 1 
ATOM   271  C CG2 . VAL A 1 90  ? 171.258 208.737 177.771 1.00 8.00   ? 89  VAL A CG2 1 
ATOM   272  N N   . THR A 1 91  ? 172.760 212.727 176.052 1.00 13.22  ? 90  THR A N   1 
ATOM   273  C CA  . THR A 1 91  ? 173.115 213.623 174.971 1.00 13.44  ? 90  THR A CA  1 
ATOM   274  C C   . THR A 1 91  ? 174.204 212.879 174.259 1.00 14.04  ? 90  THR A C   1 
ATOM   275  O O   . THR A 1 91  ? 175.147 212.420 174.902 1.00 15.65  ? 90  THR A O   1 
ATOM   276  C CB  . THR A 1 91  ? 173.618 215.004 175.432 1.00 14.78  ? 90  THR A CB  1 
ATOM   277  O OG1 . THR A 1 91  ? 172.594 215.662 176.171 1.00 17.50  ? 90  THR A OG1 1 
ATOM   278  C CG2 . THR A 1 91  ? 173.977 215.864 174.210 1.00 15.07  ? 90  THR A CG2 1 
ATOM   279  N N   . GLU A 1 92  ? 174.086 212.746 172.956 1.00 14.60  ? 91  GLU A N   1 
ATOM   280  C CA  . GLU A 1 92  ? 175.074 211.981 172.215 1.00 13.41  ? 91  GLU A CA  1 
ATOM   281  C C   . GLU A 1 92  ? 175.602 212.769 171.050 1.00 13.71  ? 91  GLU A C   1 
ATOM   282  O O   . GLU A 1 92  ? 174.922 213.643 170.529 1.00 16.56  ? 91  GLU A O   1 
ATOM   283  C CB  . GLU A 1 92  ? 174.442 210.663 171.756 1.00 12.27  ? 91  GLU A CB  1 
ATOM   284  C CG  . GLU A 1 92  ? 175.299 209.734 170.954 1.00 13.02  ? 91  GLU A CG  1 
ATOM   285  C CD  . GLU A 1 92  ? 176.452 209.239 171.704 1.00 15.11  ? 91  GLU A CD  1 
ATOM   286  O OE1 . GLU A 1 92  ? 177.366 210.009 171.937 1.00 16.84  ? 91  GLU A OE1 1 
ATOM   287  O OE2 . GLU A 1 92  ? 176.460 208.086 172.023 1.00 15.36  ? 91  GLU A OE2 1 
ATOM   288  N N   . GLU A 1 93  ? 176.826 212.473 170.659 1.00 15.28  ? 92  GLU A N   1 
ATOM   289  C CA  . GLU A 1 93  ? 177.488 213.122 169.535 1.00 13.82  ? 92  GLU A CA  1 
ATOM   290  C C   . GLU A 1 93  ? 177.300 212.326 168.253 1.00 13.60  ? 92  GLU A C   1 
ATOM   291  O O   . GLU A 1 93  ? 177.737 211.177 168.142 1.00 14.15  ? 92  GLU A O   1 
ATOM   292  C CB  . GLU A 1 93  ? 178.976 213.238 169.840 1.00 16.70  ? 92  GLU A CB  1 
ATOM   293  C CG  . GLU A 1 93  ? 179.821 213.982 168.823 1.00 17.18  ? 92  GLU A CG  1 
ATOM   294  C CD  . GLU A 1 93  ? 179.719 215.469 168.918 1.00 19.45  ? 92  GLU A CD  1 
ATOM   295  O OE1 . GLU A 1 93  ? 179.324 215.960 169.943 1.00 19.17  ? 92  GLU A OE1 1 
ATOM   296  O OE2 . GLU A 1 93  ? 180.064 216.127 167.967 1.00 21.09  ? 92  GLU A OE2 1 
ATOM   297  N N   . PHE A 1 94  ? 176.681 212.938 167.264 1.00 14.43  ? 93  PHE A N   1 
ATOM   298  C CA  . PHE A 1 94  ? 176.421 212.283 165.995 1.00 12.22  ? 93  PHE A CA  1 
ATOM   299  C C   . PHE A 1 94  ? 177.285 212.877 164.896 1.00 12.39  ? 93  PHE A C   1 
ATOM   300  O O   . PHE A 1 94  ? 177.696 214.038 164.978 1.00 15.11  ? 93  PHE A O   1 
ATOM   301  C CB  . PHE A 1 94  ? 174.947 212.376 165.661 1.00 10.70  ? 93  PHE A CB  1 
ATOM   302  C CG  . PHE A 1 94  ? 174.023 211.462 166.436 1.00 10.07  ? 93  PHE A CG  1 
ATOM   303  C CD1 . PHE A 1 94  ? 173.604 211.758 167.701 1.00 11.37  ? 93  PHE A CD1 1 
ATOM   304  C CD2 . PHE A 1 94  ? 173.537 210.316 165.855 1.00 7.99   ? 93  PHE A CD2 1 
ATOM   305  C CE1 . PHE A 1 94  ? 172.751 210.918 168.364 1.00 9.09   ? 93  PHE A CE1 1 
ATOM   306  C CE2 . PHE A 1 94  ? 172.680 209.486 166.529 1.00 7.42   ? 93  PHE A CE2 1 
ATOM   307  C CZ  . PHE A 1 94  ? 172.298 209.787 167.782 1.00 7.90   ? 93  PHE A CZ  1 
ATOM   308  N N   . ASN A 1 95  ? 177.617 212.073 163.887 1.00 13.32  ? 94  ASN A N   1 
ATOM   309  C CA  . ASN A 1 95  ? 178.396 212.605 162.782 1.00 13.38  ? 94  ASN A CA  1 
ATOM   310  C C   . ASN A 1 95  ? 178.118 211.910 161.453 1.00 13.63  ? 94  ASN A C   1 
ATOM   311  O O   . ASN A 1 95  ? 178.833 210.973 161.083 1.00 16.56  ? 94  ASN A O   1 
ATOM   312  C CB  . ASN A 1 95  ? 179.872 212.526 163.119 1.00 15.91  ? 94  ASN A CB  1 
ATOM   313  C CG  . ASN A 1 95  ? 180.767 213.252 162.164 1.00 15.70  ? 94  ASN A CG  1 
ATOM   314  O OD1 . ASN A 1 95  ? 180.329 214.017 161.315 1.00 15.48  ? 94  ASN A OD1 1 
ATOM   315  N ND2 . ASN A 1 95  ? 182.037 213.057 162.324 1.00 19.28  ? 94  ASN A ND2 1 
ATOM   316  N N   . MET A 1 96  ? 177.103 212.361 160.724 1.00 13.34  ? 95  MET A N   1 
ATOM   317  C CA  . MET A 1 96  ? 176.823 211.745 159.446 1.00 12.59  ? 95  MET A CA  1 
ATOM   318  C C   . MET A 1 96  ? 178.072 212.050 158.635 1.00 16.21  ? 95  MET A C   1 
ATOM   319  O O   . MET A 1 96  ? 178.831 212.929 159.006 1.00 19.76  ? 95  MET A O   1 
ATOM   320  C CB  . MET A 1 96  ? 175.551 212.270 158.794 1.00 12.62  ? 95  MET A CB  1 
ATOM   321  C CG  . MET A 1 96  ? 175.657 213.613 158.245 1.00 13.27  ? 95  MET A CG  1 
ATOM   322  S SD  . MET A 1 96  ? 174.182 214.256 157.511 1.00 11.35  ? 95  MET A SD  1 
ATOM   323  C CE  . MET A 1 96  ? 174.036 213.380 156.029 1.00 11.98  ? 95  MET A CE  1 
ATOM   324  N N   . TRP A 1 97  ? 178.324 211.303 157.578 1.00 15.05  ? 96  TRP A N   1 
ATOM   325  C CA  . TRP A 1 97  ? 179.538 211.412 156.742 1.00 16.14  ? 96  TRP A CA  1 
ATOM   326  C C   . TRP A 1 97  ? 180.672 210.554 157.306 1.00 18.29  ? 96  TRP A C   1 
ATOM   327  O O   . TRP A 1 97  ? 181.554 210.147 156.553 1.00 22.32  ? 96  TRP A O   1 
ATOM   328  C CB  . TRP A 1 97  ? 180.041 212.871 156.497 1.00 16.34  ? 96  TRP A CB  1 
ATOM   329  C CG  . TRP A 1 97  ? 179.042 213.754 155.758 1.00 15.71  ? 96  TRP A CG  1 
ATOM   330  C CD1 . TRP A 1 97  ? 178.658 213.614 154.465 1.00 15.92  ? 96  TRP A CD1 1 
ATOM   331  C CD2 . TRP A 1 97  ? 178.319 214.868 156.250 1.00 13.90  ? 96  TRP A CD2 1 
ATOM   332  N NE1 . TRP A 1 97  ? 177.727 214.541 154.144 1.00 13.70  ? 96  TRP A NE1 1 
ATOM   333  C CE2 . TRP A 1 97  ? 177.489 215.301 155.216 1.00 13.60  ? 96  TRP A CE2 1 
ATOM   334  C CE3 . TRP A 1 97  ? 178.283 215.518 157.457 1.00 13.52  ? 96  TRP A CE3 1 
ATOM   335  C CZ2 . TRP A 1 97  ? 176.631 216.320 155.378 1.00 15.41  ? 96  TRP A CZ2 1 
ATOM   336  C CZ3 . TRP A 1 97  ? 177.415 216.549 157.604 1.00 15.14  ? 96  TRP A CZ3 1 
ATOM   337  C CH2 . TRP A 1 97  ? 176.613 216.928 156.617 1.00 16.89  ? 96  TRP A CH2 1 
ATOM   338  N N   . LYS A 1 98  ? 180.614 210.203 158.595 1.00 18.00  ? 97  LYS A N   1 
ATOM   339  C CA  . LYS A 1 98  ? 181.561 209.270 159.204 1.00 17.89  ? 97  LYS A CA  1 
ATOM   340  C C   . LYS A 1 98  ? 180.798 208.055 159.716 1.00 17.86  ? 97  LYS A C   1 
ATOM   341  O O   . LYS A 1 98  ? 181.298 207.263 160.514 1.00 21.42  ? 97  LYS A O   1 
ATOM   342  C CB  . LYS A 1 98  ? 182.354 209.930 160.319 1.00 20.55  ? 97  LYS A CB  1 
ATOM   343  C CG  . LYS A 1 98  ? 183.185 211.140 159.884 1.00 23.41  ? 97  LYS A CG  1 
ATOM   344  C CD  . LYS A 1 98  ? 184.292 210.789 158.908 1.00 29.83  ? 97  LYS A CD  1 
ATOM   345  C CE  . LYS A 1 98  ? 185.134 212.007 158.581 1.00 36.15  ? 97  LYS A CE  1 
ATOM   346  N NZ  . LYS A 1 98  ? 186.210 211.695 157.593 1.00 50.36  ? 97  LYS A NZ  1 
ATOM   347  N N   . ASN A 1 99  ? 179.564 207.953 159.261 1.00 16.70  ? 98  ASN A N   1 
ATOM   348  C CA  . ASN A 1 99  ? 178.607 206.919 159.601 1.00 15.68  ? 98  ASN A CA  1 
ATOM   349  C C   . ASN A 1 99  ? 178.772 205.708 158.702 1.00 15.62  ? 98  ASN A C   1 
ATOM   350  O O   . ASN A 1 99  ? 178.395 205.749 157.535 1.00 17.53  ? 98  ASN A O   1 
ATOM   351  C CB  . ASN A 1 99  ? 177.202 207.471 159.492 1.00 14.47  ? 98  ASN A CB  1 
ATOM   352  C CG  . ASN A 1 99  ? 176.160 206.518 159.904 1.00 12.99  ? 98  ASN A CG  1 
ATOM   353  O OD1 . ASN A 1 99  ? 176.440 205.336 160.143 1.00 14.98  ? 98  ASN A OD1 1 
ATOM   354  N ND2 . ASN A 1 99  ? 174.947 206.978 159.968 1.00 11.62  ? 98  ASN A ND2 1 
ATOM   355  N N   . ASN A 1 100 ? 179.271 204.605 159.245 1.00 16.61  ? 99  ASN A N   1 
ATOM   356  C CA  . ASN A 1 100 ? 179.596 203.434 158.439 1.00 15.68  ? 99  ASN A CA  1 
ATOM   357  C C   . ASN A 1 100 ? 178.372 202.627 158.037 1.00 15.75  ? 99  ASN A C   1 
ATOM   358  O O   . ASN A 1 100 ? 178.487 201.652 157.291 1.00 18.54  ? 99  ASN A O   1 
ATOM   359  C CB  . ASN A 1 100 ? 180.554 202.533 159.181 1.00 20.11  ? 99  ASN A CB  1 
ATOM   360  C CG  . ASN A 1 100 ? 181.280 201.576 158.280 1.00 22.83  ? 99  ASN A CG  1 
ATOM   361  O OD1 . ASN A 1 100 ? 181.911 201.982 157.295 1.00 23.50  ? 99  ASN A OD1 1 
ATOM   362  N ND2 . ASN A 1 100 ? 181.196 200.314 158.590 1.00 22.75  ? 99  ASN A ND2 1 
ATOM   363  N N   . MET A 1 101 ? 177.195 203.049 158.480 1.00 15.55  ? 100 MET A N   1 
ATOM   364  C CA  . MET A 1 101 ? 175.975 202.374 158.094 1.00 12.94  ? 100 MET A CA  1 
ATOM   365  C C   . MET A 1 101 ? 175.727 202.666 156.631 1.00 13.79  ? 100 MET A C   1 
ATOM   366  O O   . MET A 1 101 ? 175.054 201.895 155.949 1.00 15.91  ? 100 MET A O   1 
ATOM   367  C CB  . MET A 1 101 ? 174.782 202.865 158.907 1.00 13.04  ? 100 MET A CB  1 
ATOM   368  C CG  . MET A 1 101 ? 174.833 202.534 160.369 1.00 11.45  ? 100 MET A CG  1 
ATOM   369  S SD  . MET A 1 101 ? 173.451 203.208 161.307 1.00 11.09  ? 100 MET A SD  1 
ATOM   370  C CE  . MET A 1 101 ? 172.050 202.180 160.984 1.00 9.08   ? 100 MET A CE  1 
ATOM   371  N N   . VAL A 1 102 ? 176.259 203.801 156.159 1.00 15.75  ? 101 VAL A N   1 
ATOM   372  C CA  . VAL A 1 102 ? 176.088 204.256 154.800 1.00 14.51  ? 101 VAL A CA  1 
ATOM   373  C C   . VAL A 1 102 ? 176.909 203.391 153.884 1.00 15.84  ? 101 VAL A C   1 
ATOM   374  O O   . VAL A 1 102 ? 176.460 203.036 152.794 1.00 17.27  ? 101 VAL A O   1 
ATOM   375  C CB  . VAL A 1 102 ? 176.491 205.721 154.683 1.00 13.04  ? 101 VAL A CB  1 
ATOM   376  C CG1 . VAL A 1 102 ? 176.446 206.180 153.215 1.00 14.89  ? 101 VAL A CG1 1 
ATOM   377  C CG2 . VAL A 1 102 ? 175.560 206.548 155.565 1.00 12.78  ? 101 VAL A CG2 1 
ATOM   378  N N   . GLU A 1 103 ? 178.129 203.088 154.303 1.00 16.89  ? 102 GLU A N   1 
ATOM   379  C CA  . GLU A 1 103 ? 179.010 202.265 153.509 1.00 16.75  ? 102 GLU A CA  1 
ATOM   380  C C   . GLU A 1 103 ? 178.466 200.860 153.430 1.00 16.46  ? 102 GLU A C   1 
ATOM   381  O O   . GLU A 1 103 ? 178.495 200.247 152.361 1.00 21.10  ? 102 GLU A O   1 
ATOM   382  C CB  . GLU A 1 103 ? 180.390 202.223 154.129 1.00 20.01  ? 102 GLU A CB  1 
ATOM   383  C CG  . GLU A 1 103 ? 181.133 203.523 154.098 1.00 22.68  ? 102 GLU A CG  1 
ATOM   384  C CD  . GLU A 1 103 ? 181.405 203.998 152.728 1.00 31.24  ? 102 GLU A CD  1 
ATOM   385  O OE1 . GLU A 1 103 ? 181.711 203.195 151.888 1.00 33.21  ? 102 GLU A OE1 1 
ATOM   386  O OE2 . GLU A 1 103 ? 181.317 205.177 152.505 1.00 32.97  ? 102 GLU A OE2 1 
ATOM   387  N N   . GLN A 1 104 ? 177.898 200.353 154.526 1.00 17.13  ? 103 GLN A N   1 
ATOM   388  C CA  . GLN A 1 104 ? 177.334 199.031 154.429 1.00 15.80  ? 103 GLN A CA  1 
ATOM   389  C C   . GLN A 1 104 ? 176.146 199.010 153.507 1.00 16.68  ? 103 GLN A C   1 
ATOM   390  O O   . GLN A 1 104 ? 176.042 198.106 152.684 1.00 21.74  ? 103 GLN A O   1 
ATOM   391  C CB  . GLN A 1 104 ? 176.894 198.461 155.759 1.00 18.65  ? 103 GLN A CB  1 
ATOM   392  C CG  . GLN A 1 104 ? 176.321 197.079 155.549 1.00 22.14  ? 103 GLN A CG  1 
ATOM   393  C CD  . GLN A 1 104 ? 175.952 196.329 156.748 1.00 22.60  ? 103 GLN A CD  1 
ATOM   394  O OE1 . GLN A 1 104 ? 176.386 196.587 157.879 1.00 23.10  ? 103 GLN A OE1 1 
ATOM   395  N NE2 . GLN A 1 104 ? 175.112 195.346 156.507 1.00 23.48  ? 103 GLN A NE2 1 
ATOM   396  N N   . MET A 1 105 ? 175.257 200.001 153.595 1.00 17.16  ? 104 MET A N   1 
ATOM   397  C CA  . MET A 1 105 ? 174.109 199.967 152.722 1.00 14.90  ? 104 MET A CA  1 
ATOM   398  C C   . MET A 1 105 ? 174.547 200.038 151.284 1.00 15.04  ? 104 MET A C   1 
ATOM   399  O O   . MET A 1 105 ? 173.998 199.346 150.435 1.00 19.64  ? 104 MET A O   1 
ATOM   400  C CB  . MET A 1 105 ? 173.119 201.070 153.043 1.00 14.89  ? 104 MET A CB  1 
ATOM   401  C CG  . MET A 1 105 ? 171.864 201.003 152.190 1.00 14.88  ? 104 MET A CG  1 
ATOM   402  S SD  . MET A 1 105 ? 170.629 202.186 152.638 1.00 15.25  ? 104 MET A SD  1 
ATOM   403  C CE  . MET A 1 105 ? 169.433 201.817 151.372 1.00 16.39  ? 104 MET A CE  1 
ATOM   404  N N   . HIS A 1 106 ? 175.561 200.830 150.985 1.00 16.41  ? 105 HIS A N   1 
ATOM   405  C CA  . HIS A 1 106 ? 176.008 200.944 149.620 1.00 14.50  ? 105 HIS A CA  1 
ATOM   406  C C   . HIS A 1 106 ? 176.441 199.598 149.079 1.00 16.44  ? 105 HIS A C   1 
ATOM   407  O O   . HIS A 1 106 ? 176.019 199.181 147.993 1.00 19.95  ? 105 HIS A O   1 
ATOM   408  C CB  . HIS A 1 106 ? 177.152 201.944 149.545 1.00 16.84  ? 105 HIS A CB  1 
ATOM   409  C CG  . HIS A 1 106 ? 177.643 202.235 148.198 1.00 17.22  ? 105 HIS A CG  1 
ATOM   410  N ND1 . HIS A 1 106 ? 176.945 203.015 147.318 1.00 17.07  ? 105 HIS A ND1 1 
ATOM   411  C CD2 . HIS A 1 106 ? 178.766 201.877 147.571 1.00 19.32  ? 105 HIS A CD2 1 
ATOM   412  C CE1 . HIS A 1 106 ? 177.618 203.125 146.204 1.00 16.77  ? 105 HIS A CE1 1 
ATOM   413  N NE2 . HIS A 1 106 ? 178.731 202.444 146.330 1.00 18.92  ? 105 HIS A NE2 1 
ATOM   414  N N   . GLU A 1 107 ? 177.254 198.883 149.843 1.00 20.64  ? 106 GLU A N   1 
ATOM   415  C CA  . GLU A 1 107 ? 177.731 197.602 149.373 1.00 18.10  ? 106 GLU A CA  1 
ATOM   416  C C   . GLU A 1 107 ? 176.622 196.558 149.299 1.00 18.27  ? 106 GLU A C   1 
ATOM   417  O O   . GLU A 1 107 ? 176.616 195.735 148.380 1.00 22.48  ? 106 GLU A O   1 
ATOM   418  C CB  . GLU A 1 107 ? 178.860 197.109 150.263 1.00 22.24  ? 106 GLU A CB  1 
ATOM   419  C CG  . GLU A 1 107 ? 180.140 197.945 150.167 1.00 26.87  ? 106 GLU A CG  1 
ATOM   420  C CD  . GLU A 1 107 ? 180.732 197.978 148.784 1.00 33.91  ? 106 GLU A CD  1 
ATOM   421  O OE1 . GLU A 1 107 ? 180.719 196.966 148.131 1.00 38.12  ? 106 GLU A OE1 1 
ATOM   422  O OE2 . GLU A 1 107 ? 181.214 199.013 148.386 1.00 32.74  ? 106 GLU A OE2 1 
ATOM   423  N N   . ASP A 1 108 ? 175.660 196.585 150.225 1.00 19.38  ? 107 ASP A N   1 
ATOM   424  C CA  . ASP A 1 108 ? 174.592 195.599 150.185 1.00 18.51  ? 107 ASP A CA  1 
ATOM   425  C C   . ASP A 1 108 ? 173.662 195.815 149.017 1.00 18.66  ? 107 ASP A C   1 
ATOM   426  O O   . ASP A 1 108 ? 173.268 194.847 148.371 1.00 26.35  ? 107 ASP A O   1 
ATOM   427  C CB  . ASP A 1 108 ? 173.730 195.645 151.441 1.00 21.98  ? 107 ASP A CB  1 
ATOM   428  C CG  . ASP A 1 108 ? 174.362 195.084 152.702 1.00 25.68  ? 107 ASP A CG  1 
ATOM   429  O OD1 . ASP A 1 108 ? 175.372 194.414 152.640 1.00 27.01  ? 107 ASP A OD1 1 
ATOM   430  O OD2 . ASP A 1 108 ? 173.800 195.324 153.746 1.00 25.18  ? 107 ASP A OD2 1 
ATOM   431  N N   . ILE A 1 109 ? 173.363 197.066 148.680 1.00 18.77  ? 108 ILE A N   1 
ATOM   432  C CA  . ILE A 1 109 ? 172.473 197.327 147.564 1.00 17.79  ? 108 ILE A CA  1 
ATOM   433  C C   . ILE A 1 109 ? 173.130 196.893 146.272 1.00 17.76  ? 108 ILE A C   1 
ATOM   434  O O   . ILE A 1 109 ? 172.464 196.304 145.417 1.00 20.05  ? 108 ILE A O   1 
ATOM   435  C CB  . ILE A 1 109 ? 172.030 198.806 147.494 1.00 17.54  ? 108 ILE A CB  1 
ATOM   436  C CG1 . ILE A 1 109 ? 171.189 199.206 148.766 1.00 17.67  ? 108 ILE A CG1 1 
ATOM   437  C CG2 . ILE A 1 109 ? 171.244 199.077 146.212 1.00 17.81  ? 108 ILE A CG2 1 
ATOM   438  C CD1 . ILE A 1 109 ? 169.906 198.422 149.034 1.00 20.59  ? 108 ILE A CD1 1 
ATOM   439  N N   . ILE A 1 110 ? 174.418 197.173 146.107 1.00 17.91  ? 109 ILE A N   1 
ATOM   440  C CA  . ILE A 1 110 ? 175.084 196.763 144.889 1.00 15.86  ? 109 ILE A CA  1 
ATOM   441  C C   . ILE A 1 110 ? 175.138 195.255 144.796 1.00 17.81  ? 109 ILE A C   1 
ATOM   442  O O   . ILE A 1 110 ? 174.865 194.705 143.732 1.00 21.79  ? 109 ILE A O   1 
ATOM   443  C CB  . ILE A 1 110 ? 176.494 197.331 144.774 1.00 15.95  ? 109 ILE A CB  1 
ATOM   444  C CG1 . ILE A 1 110 ? 176.385 198.811 144.619 1.00 15.84  ? 109 ILE A CG1 1 
ATOM   445  C CG2 . ILE A 1 110 ? 177.190 196.709 143.534 1.00 17.25  ? 109 ILE A CG2 1 
ATOM   446  C CD1 . ILE A 1 110 ? 177.641 199.555 144.772 1.00 15.20  ? 109 ILE A CD1 1 
ATOM   447  N N   . SER A 1 111 ? 175.481 194.574 145.888 1.00 20.95  ? 110 SER A N   1 
ATOM   448  C CA  . SER A 1 111 ? 175.562 193.127 145.859 1.00 19.78  ? 110 SER A CA  1 
ATOM   449  C C   . SER A 1 111 ? 174.234 192.491 145.515 1.00 19.02  ? 110 SER A C   1 
ATOM   450  O O   . SER A 1 111 ? 174.190 191.598 144.671 1.00 26.99  ? 110 SER A O   1 
ATOM   451  C CB  . SER A 1 111 ? 176.033 192.609 147.194 1.00 23.21  ? 110 SER A CB  1 
ATOM   452  O OG  . SER A 1 111 ? 176.126 191.206 147.199 1.00 27.78  ? 110 SER A OG  1 
ATOM   453  N N   . LEU A 1 112 ? 173.143 192.953 146.113 1.00 22.13  ? 111 LEU A N   1 
ATOM   454  C CA  . LEU A 1 112 ? 171.849 192.366 145.823 1.00 22.12  ? 111 LEU A CA  1 
ATOM   455  C C   . LEU A 1 112 ? 171.467 192.628 144.369 1.00 20.06  ? 111 LEU A C   1 
ATOM   456  O O   . LEU A 1 112 ? 170.906 191.747 143.704 1.00 24.20  ? 111 LEU A O   1 
ATOM   457  C CB  . LEU A 1 112 ? 170.811 192.923 146.803 1.00 25.37  ? 111 LEU A CB  1 
ATOM   458  C CG  . LEU A 1 112 ? 170.978 192.474 148.316 1.00 31.87  ? 111 LEU A CG  1 
ATOM   459  C CD1 . LEU A 1 112 ? 170.044 193.296 149.193 1.00 34.13  ? 111 LEU A CD1 1 
ATOM   460  C CD2 . LEU A 1 112 ? 170.661 190.972 148.489 1.00 38.91  ? 111 LEU A CD2 1 
ATOM   461  N N   . TRP A 1 113 ? 171.797 193.815 143.855 1.00 21.49  ? 112 TRP A N   1 
ATOM   462  C CA  . TRP A 1 113 ? 171.535 194.135 142.465 1.00 20.02  ? 112 TRP A CA  1 
ATOM   463  C C   . TRP A 1 113 ? 172.229 193.125 141.568 1.00 18.89  ? 112 TRP A C   1 
ATOM   464  O O   . TRP A 1 113 ? 171.611 192.523 140.695 1.00 20.93  ? 112 TRP A O   1 
ATOM   465  C CB  . TRP A 1 113 ? 172.063 195.525 142.116 1.00 20.69  ? 112 TRP A CB  1 
ATOM   466  C CG  . TRP A 1 113 ? 171.813 195.925 140.724 1.00 20.78  ? 112 TRP A CG  1 
ATOM   467  C CD1 . TRP A 1 113 ? 172.627 195.740 139.653 1.00 20.13  ? 112 TRP A CD1 1 
ATOM   468  C CD2 . TRP A 1 113 ? 170.667 196.619 140.237 1.00 20.89  ? 112 TRP A CD2 1 
ATOM   469  N NE1 . TRP A 1 113 ? 172.050 196.257 138.542 1.00 20.50  ? 112 TRP A NE1 1 
ATOM   470  C CE2 . TRP A 1 113 ? 170.848 196.798 138.882 1.00 20.92  ? 112 TRP A CE2 1 
ATOM   471  C CE3 . TRP A 1 113 ? 169.516 197.099 140.838 1.00 23.23  ? 112 TRP A CE3 1 
ATOM   472  C CZ2 . TRP A 1 113 ? 169.919 197.435 138.109 1.00 22.65  ? 112 TRP A CZ2 1 
ATOM   473  C CZ3 . TRP A 1 113 ? 168.588 197.748 140.059 1.00 24.83  ? 112 TRP A CZ3 1 
ATOM   474  C CH2 . TRP A 1 113 ? 168.792 197.911 138.726 1.00 23.61  ? 112 TRP A CH2 1 
ATOM   475  N N   . ASP A 1 114 ? 173.527 192.904 141.792 1.00 23.87  ? 113 ASP A N   1 
ATOM   476  C CA  . ASP A 1 114 ? 174.275 191.979 140.951 1.00 20.88  ? 113 ASP A CA  1 
ATOM   477  C C   . ASP A 1 114 ? 173.773 190.557 141.054 1.00 20.79  ? 113 ASP A C   1 
ATOM   478  O O   . ASP A 1 114 ? 173.698 189.851 140.051 1.00 25.30  ? 113 ASP A O   1 
ATOM   479  C CB  . ASP A 1 114 ? 175.758 191.986 141.310 1.00 21.31  ? 113 ASP A CB  1 
ATOM   480  C CG  . ASP A 1 114 ? 176.509 193.217 140.843 1.00 21.61  ? 113 ASP A CG  1 
ATOM   481  O OD1 . ASP A 1 114 ? 175.994 193.939 140.020 1.00 21.86  ? 113 ASP A OD1 1 
ATOM   482  O OD2 . ASP A 1 114 ? 177.615 193.417 141.296 1.00 22.70  ? 113 ASP A OD2 1 
ATOM   483  N N   . GLN A 1 115 ? 173.354 190.136 142.237 1.00 24.33  ? 114 GLN A N   1 
ATOM   484  C CA  . GLN A 1 115 ? 172.870 188.777 142.400 1.00 23.83  ? 114 GLN A CA  1 
ATOM   485  C C   . GLN A 1 115 ? 171.641 188.529 141.551 1.00 22.54  ? 114 GLN A C   1 
ATOM   486  O O   . GLN A 1 115 ? 171.501 187.457 140.961 1.00 27.13  ? 114 GLN A O   1 
ATOM   487  C CB  . GLN A 1 115 ? 172.508 188.492 143.861 1.00 26.10  ? 114 GLN A CB  1 
ATOM   488  C CG  . GLN A 1 115 ? 173.676 188.388 144.831 1.00 29.44  ? 114 GLN A CG  1 
ATOM   489  C CD  . GLN A 1 115 ? 173.191 188.293 146.279 1.00 32.53  ? 114 GLN A CD  1 
ATOM   490  O OE1 . GLN A 1 115 ? 172.228 187.569 146.553 1.00 37.59  ? 114 GLN A OE1 1 
ATOM   491  N NE2 . GLN A 1 115 ? 173.823 189.017 147.200 1.00 35.40  ? 114 GLN A NE2 1 
ATOM   492  N N   . SER A 1 116 ? 170.785 189.536 141.412 1.00 23.34  ? 115 SER A N   1 
ATOM   493  C CA  . SER A 1 116 ? 169.538 189.378 140.680 1.00 22.20  ? 115 SER A CA  1 
ATOM   494  C C   . SER A 1 116 ? 169.746 189.173 139.187 1.00 22.22  ? 115 SER A C   1 
ATOM   495  O O   . SER A 1 116 ? 168.813 188.775 138.494 1.00 24.37  ? 115 SER A O   1 
ATOM   496  C CB  . SER A 1 116 ? 168.630 190.578 140.855 1.00 21.87  ? 115 SER A CB  1 
ATOM   497  O OG  . SER A 1 116 ? 169.061 191.677 140.093 1.00 21.97  ? 115 SER A OG  1 
ATOM   498  N N   . LEU A 1 117 ? 170.935 189.482 138.665 1.00 22.79  ? 116 LEU A N   1 
ATOM   499  C CA  . LEU A 1 117 ? 171.187 189.319 137.247 1.00 21.91  ? 116 LEU A CA  1 
ATOM   500  C C   . LEU A 1 117 ? 171.872 188.007 136.919 1.00 24.32  ? 116 LEU A C   1 
ATOM   501  O O   . LEU A 1 117 ? 172.020 187.660 135.746 1.00 26.08  ? 116 LEU A O   1 
ATOM   502  C CB  . LEU A 1 117 ? 172.029 190.485 136.714 1.00 21.29  ? 116 LEU A CB  1 
ATOM   503  C CG  . LEU A 1 117 ? 171.383 191.900 136.766 1.00 18.86  ? 116 LEU A CG  1 
ATOM   504  C CD1 . LEU A 1 117 ? 172.397 192.930 136.345 1.00 17.23  ? 116 LEU A CD1 1 
ATOM   505  C CD2 . LEU A 1 117 ? 170.188 191.967 135.810 1.00 19.51  ? 116 LEU A CD2 1 
ATOM   506  N N   . LYS A 1 118 ? 172.289 187.252 137.935 1.00 27.08  ? 117 LYS A N   1 
ATOM   507  C CA  . LYS A 1 118 ? 173.027 186.034 137.661 1.00 27.07  ? 117 LYS A CA  1 
ATOM   508  C C   . LYS A 1 118 ? 172.282 185.011 136.808 1.00 27.60  ? 117 LYS A C   1 
ATOM   509  O O   . LYS A 1 118 ? 172.909 184.390 135.955 1.00 28.05  ? 117 LYS A O   1 
ATOM   510  C CB  . LYS A 1 118 ? 173.561 185.391 138.936 1.00 28.73  ? 117 LYS A CB  1 
ATOM   511  C CG  . LYS A 1 118 ? 174.714 186.148 139.555 1.00 30.36  ? 117 LYS A CG  1 
ATOM   512  C CD  . LYS A 1 118 ? 175.229 185.460 140.808 1.00 35.58  ? 117 LYS A CD  1 
ATOM   513  C CE  . LYS A 1 118 ? 176.392 186.230 141.427 1.00 43.58  ? 117 LYS A CE  1 
ATOM   514  N NZ  . LYS A 1 118 ? 176.946 185.539 142.632 1.00 51.16  ? 117 LYS A NZ  1 
ATOM   515  N N   . PRO A 1 119 ? 170.978 184.751 137.007 1.00 26.60  ? 118 PRO A N   1 
ATOM   516  C CA  . PRO A 1 119 ? 170.220 183.805 136.219 1.00 28.44  ? 118 PRO A CA  1 
ATOM   517  C C   . PRO A 1 119 ? 169.590 184.338 134.915 1.00 28.20  ? 118 PRO A C   1 
ATOM   518  O O   . PRO A 1 119 ? 168.754 183.632 134.345 1.00 28.58  ? 118 PRO A O   1 
ATOM   519  C CB  . PRO A 1 119 ? 169.135 183.393 137.214 1.00 30.98  ? 118 PRO A CB  1 
ATOM   520  C CG  . PRO A 1 119 ? 168.850 184.641 137.990 1.00 28.45  ? 118 PRO A CG  1 
ATOM   521  C CD  . PRO A 1 119 ? 170.178 185.347 138.122 1.00 26.66  ? 118 PRO A CD  1 
ATOM   522  N N   . CYS A 1 120 ? 169.924 185.580 134.471 1.00 27.79  ? 119 CYS A N   1 
ATOM   523  C CA  . CYS A 1 120 ? 169.271 186.237 133.345 1.00 24.63  ? 119 CYS A CA  1 
ATOM   524  C C   . CYS A 1 120 ? 170.066 186.021 132.051 1.00 20.96  ? 119 CYS A C   1 
ATOM   525  O O   . CYS A 1 120 ? 171.256 185.699 132.070 1.00 21.53  ? 119 CYS A O   1 
ATOM   526  C CB  . CYS A 1 120 ? 169.084 187.738 133.630 1.00 21.83  ? 119 CYS A CB  1 
ATOM   527  S SG  . CYS A 1 120 ? 168.091 188.127 135.136 1.00 26.17  ? 119 CYS A SG  1 
ATOM   528  N N   . VAL A 1 121 ? 169.398 186.182 130.914 1.00 19.85  ? 120 VAL A N   1 
ATOM   529  C CA  . VAL A 1 121 ? 170.036 185.974 129.616 1.00 18.15  ? 120 VAL A CA  1 
ATOM   530  C C   . VAL A 1 121 ? 171.121 186.982 129.330 1.00 15.74  ? 120 VAL A C   1 
ATOM   531  O O   . VAL A 1 121 ? 170.883 188.182 129.404 1.00 17.61  ? 120 VAL A O   1 
ATOM   532  C CB  . VAL A 1 121 ? 168.964 186.078 128.506 1.00 16.19  ? 120 VAL A CB  1 
ATOM   533  C CG1 . VAL A 1 121 ? 169.578 186.012 127.127 1.00 17.75  ? 120 VAL A CG1 1 
ATOM   534  C CG2 . VAL A 1 121 ? 167.990 184.960 128.659 1.00 17.97  ? 120 VAL A CG2 1 
ATOM   535  N N   . LYS A 1 122 ? 172.295 186.484 128.953 1.00 17.86  ? 121 LYS A N   1 
ATOM   536  C CA  . LYS A 1 122 ? 173.429 187.325 128.627 1.00 17.27  ? 121 LYS A CA  1 
ATOM   537  C C   . LYS A 1 122 ? 173.387 187.592 127.129 1.00 17.49  ? 121 LYS A C   1 
ATOM   538  O O   . LYS A 1 122 ? 173.384 186.662 126.324 1.00 19.71  ? 121 LYS A O   1 
ATOM   539  C CB  . LYS A 1 122 ? 174.714 186.645 129.062 1.00 20.97  ? 121 LYS A CB  1 
ATOM   540  C CG  . LYS A 1 122 ? 175.933 187.507 128.986 1.00 25.56  ? 121 LYS A CG  1 
ATOM   541  C CD  . LYS A 1 122 ? 177.150 186.731 129.468 1.00 37.43  ? 121 LYS A CD  1 
ATOM   542  C CE  . LYS A 1 122 ? 178.412 187.563 129.429 1.00 47.26  ? 121 LYS A CE  1 
ATOM   543  N NZ  . LYS A 1 122 ? 179.592 186.793 129.931 1.00 47.96  ? 121 LYS A NZ  1 
ATOM   544  N N   . LEU A 1 123 ? 173.369 188.849 126.727 1.00 16.68  ? 122 LEU A N   1 
ATOM   545  C CA  . LEU A 1 123 ? 173.170 189.175 125.327 1.00 16.40  ? 122 LEU A CA  1 
ATOM   546  C C   . LEU A 1 123 ? 174.427 189.261 124.498 1.00 17.89  ? 122 LEU A C   1 
ATOM   547  O O   . LEU A 1 123 ? 174.727 190.303 123.918 1.00 18.04  ? 122 LEU A O   1 
ATOM   548  C CB  . LEU A 1 123 ? 172.453 190.514 125.236 1.00 15.36  ? 122 LEU A CB  1 
ATOM   549  C CG  . LEU A 1 123 ? 171.087 190.633 125.937 1.00 12.60  ? 122 LEU A CG  1 
ATOM   550  C CD1 . LEU A 1 123 ? 170.599 192.046 125.765 1.00 10.74  ? 122 LEU A CD1 1 
ATOM   551  C CD2 . LEU A 1 123 ? 170.077 189.620 125.379 1.00 13.09  ? 122 LEU A CD2 1 
ATOM   552  N N   . THR A 1 124 ? 175.123 188.148 124.372 1.00 20.59  ? 123 THR A N   1 
ATOM   553  C CA  . THR A 1 124 ? 176.335 188.132 123.568 1.00 20.42  ? 123 THR A CA  1 
ATOM   554  C C   . THR A 1 124 ? 176.049 187.895 122.085 1.00 19.51  ? 123 THR A C   1 
ATOM   555  O O   . THR A 1 124 ? 176.758 188.467 121.257 1.00 21.87  ? 123 THR A O   1 
ATOM   556  C CB  . THR A 1 124 ? 177.382 187.118 124.076 1.00 22.75  ? 123 THR A CB  1 
ATOM   557  O OG1 . THR A 1 124 ? 176.866 185.794 124.043 1.00 23.70  ? 123 THR A OG1 1 
ATOM   558  C CG2 . THR A 1 124 ? 177.726 187.450 125.470 1.00 26.36  ? 123 THR A CG2 1 
ATOM   559  N N   . PRO A 1 125 ? 174.979 187.161 121.675 1.00 19.57  ? 124 PRO A N   1 
ATOM   560  C CA  . PRO A 1 125 ? 174.612 186.929 120.302 1.00 19.98  ? 124 PRO A CA  1 
ATOM   561  C C   . PRO A 1 125 ? 174.258 188.205 119.581 1.00 17.95  ? 124 PRO A C   1 
ATOM   562  O O   . PRO A 1 125 ? 174.186 188.233 118.361 1.00 19.94  ? 124 PRO A O   1 
ATOM   563  C CB  . PRO A 1 125 ? 173.396 186.024 120.409 1.00 20.46  ? 124 PRO A CB  1 
ATOM   564  C CG  . PRO A 1 125 ? 173.525 185.366 121.716 1.00 19.56  ? 124 PRO A CG  1 
ATOM   565  C CD  . PRO A 1 125 ? 174.101 186.393 122.602 1.00 20.27  ? 124 PRO A CD  1 
ATOM   566  N N   . LEU A 1 126 ? 174.002 189.260 120.332 1.00 19.96  ? 125 LEU A N   1 
ATOM   567  C CA  . LEU A 1 126 ? 173.598 190.509 119.730 1.00 18.48  ? 125 LEU A CA  1 
ATOM   568  C C   . LEU A 1 126 ? 174.712 191.522 119.425 1.00 17.89  ? 125 LEU A C   1 
ATOM   569  O O   . LEU A 1 126 ? 174.405 192.581 118.865 1.00 18.79  ? 125 LEU A O   1 
ATOM   570  C CB  . LEU A 1 126 ? 172.532 191.123 120.615 1.00 19.09  ? 125 LEU A CB  1 
ATOM   571  C CG  . LEU A 1 126 ? 171.274 190.224 120.837 1.00 14.75  ? 125 LEU A CG  1 
ATOM   572  C CD1 . LEU A 1 126 ? 170.407 190.899 121.713 1.00 16.36  ? 125 LEU A CD1 1 
ATOM   573  C CD2 . LEU A 1 126 ? 170.532 189.912 119.555 1.00 15.60  ? 125 LEU A CD2 1 
ATOM   574  N N   . CYS A 1 127 ? 175.948 191.161 119.722 1.00 19.33  ? 126 CYS A N   1 
ATOM   575  C CA  . CYS A 1 127 ? 177.139 191.964 119.395 1.00 17.42  ? 126 CYS A CA  1 
ATOM   576  C C   . CYS A 1 127 ? 177.472 191.680 117.949 1.00 15.55  ? 126 CYS A C   1 
ATOM   577  O O   . CYS A 1 127 ? 178.450 191.017 117.729 1.00 19.95  ? 126 CYS A O   1 
ATOM   578  C CB  . CYS A 1 127 ? 178.293 191.636 120.323 1.00 19.01  ? 126 CYS A CB  1 
ATOM   579  S SG  . CYS A 1 127 ? 178.451 192.790 121.714 1.00 24.29  ? 126 CYS A SG  1 
ATOM   580  N N   . VAL A 1 128 ? 176.686 192.189 117.024 1.00 18.96  ? 127 VAL A N   1 
ATOM   581  C CA  . VAL A 1 128 ? 176.745 192.033 115.591 1.00 17.43  ? 127 VAL A CA  1 
ATOM   582  C C   . VAL A 1 128 ? 176.576 193.393 114.983 1.00 16.75  ? 127 VAL A C   1 
ATOM   583  O O   . VAL A 1 128 ? 176.200 194.335 115.674 1.00 17.46  ? 127 VAL A O   1 
ATOM   584  C CB  . VAL A 1 128 ? 175.644 191.080 115.089 1.00 18.02  ? 127 VAL A CB  1 
ATOM   585  C CG1 . VAL A 1 128 ? 175.832 189.741 115.707 1.00 18.86  ? 127 VAL A CG1 1 
ATOM   586  C CG2 . VAL A 1 128 ? 174.251 191.622 115.425 1.00 17.56  ? 127 VAL A CG2 1 
ATOM   587  N N   . THR A 1 129 ? 176.867 193.524 113.713 1.00 18.60  ? 128 THR A N   1 
ATOM   588  C CA  . THR A 1 129 ? 176.647 194.800 113.089 1.00 16.87  ? 128 THR A CA  1 
ATOM   589  C C   . THR A 1 129 ? 175.162 194.964 112.875 1.00 17.70  ? 128 THR A C   1 
ATOM   590  O O   . THR A 1 129 ? 174.471 193.995 112.565 1.00 18.48  ? 128 THR A O   1 
ATOM   591  C CB  . THR A 1 129 ? 177.345 194.848 111.735 1.00 19.13  ? 128 THR A CB  1 
ATOM   592  O OG1 . THR A 1 129 ? 176.809 193.829 110.910 1.00 23.22  ? 128 THR A OG1 1 
ATOM   593  C CG2 . THR A 1 129 ? 178.813 194.580 111.890 1.00 22.63  ? 128 THR A CG2 1 
ATOM   594  N N   . LEU A 1 130 ? 174.650 196.162 113.075 1.00 17.47  ? 129 LEU A N   1 
ATOM   595  C CA  . LEU A 1 130 ? 173.218 196.427 112.928 1.00 14.35  ? 129 LEU A CA  1 
ATOM   596  C C   . LEU A 1 130 ? 173.139 197.365 111.744 1.00 15.48  ? 129 LEU A C   1 
ATOM   597  O O   . LEU A 1 130 ? 174.100 198.065 111.542 1.00 19.99  ? 129 LEU A O   1 
ATOM   598  C CB  . LEU A 1 130 ? 172.732 197.096 114.209 1.00 13.57  ? 129 LEU A CB  1 
ATOM   599  C CG  . LEU A 1 130 ? 173.114 196.501 115.554 1.00 12.14  ? 129 LEU A CG  1 
ATOM   600  C CD1 . LEU A 1 130 ? 172.951 197.560 116.625 1.00 11.56  ? 129 LEU A CD1 1 
ATOM   601  C CD2 . LEU A 1 130 ? 172.242 195.309 115.876 1.00 11.95  ? 129 LEU A CD2 1 
ATOM   602  N N   . GLN A 1 131 ? 172.098 197.267 110.928 1.00 17.89  ? 130 GLN A N   1 
ATOM   603  C CA  . GLN A 1 131 ? 171.923 198.208 109.804 1.00 18.78  ? 130 GLN A CA  1 
ATOM   604  C C   . GLN A 1 131 ? 170.756 199.101 110.166 1.00 18.03  ? 130 GLN A C   1 
ATOM   605  O O   . GLN A 1 131 ? 169.635 198.640 110.070 1.00 18.56  ? 130 GLN A O   1 
ATOM   606  C CB  . GLN A 1 131 ? 171.810 197.479 108.479 1.00 22.43  ? 130 GLN A CB  1 
ATOM   607  C CG  . GLN A 1 131 ? 173.144 197.003 107.935 1.00 25.84  ? 130 GLN A CG  1 
ATOM   608  C CD  . GLN A 1 131 ? 172.938 195.979 106.848 1.00 32.94  ? 130 GLN A CD  1 
ATOM   609  O OE1 . GLN A 1 131 ? 171.811 195.618 106.522 1.00 33.59  ? 130 GLN A OE1 1 
ATOM   610  N NE2 . GLN A 1 131 ? 174.033 195.495 106.287 1.00 36.65  ? 130 GLN A NE2 1 
ATOM   611  N N   . CYS A 1 132 ? 171.031 200.374 110.446 1.00 21.91  ? 131 CYS A N   1 
ATOM   612  C CA  . CYS A 1 132 ? 170.000 201.279 111.009 1.00 20.05  ? 131 CYS A CA  1 
ATOM   613  C C   . CYS A 1 132 ? 169.586 202.405 110.082 1.00 20.93  ? 131 CYS A C   1 
ATOM   614  O O   . CYS A 1 132 ? 170.468 203.090 109.578 1.00 24.55  ? 131 CYS A O   1 
ATOM   615  C CB  . CYS A 1 132 ? 170.544 201.869 112.301 1.00 17.08  ? 131 CYS A CB  1 
ATOM   616  S SG  . CYS A 1 132 ? 171.007 200.614 113.518 1.00 16.98  ? 131 CYS A SG  1 
ATOM   617  N N   . THR A 1 133 ? 168.283 202.576 109.887 1.00 20.26  ? 132 THR A N   1 
ATOM   618  C CA  . THR A 1 133 ? 167.704 203.645 109.095 1.00 22.58  ? 132 THR A CA  1 
ATOM   619  C C   . THR A 1 133 ? 166.740 204.430 109.990 1.00 23.21  ? 132 THR A C   1 
ATOM   620  O O   . THR A 1 133 ? 166.448 203.983 111.103 1.00 22.90  ? 132 THR A O   1 
ATOM   621  C CB  . THR A 1 133 ? 166.986 203.081 107.849 1.00 24.76  ? 132 THR A CB  1 
ATOM   622  O OG1 . THR A 1 133 ? 165.865 202.284 108.253 1.00 22.88  ? 132 THR A OG1 1 
ATOM   623  C CG2 . THR A 1 133 ? 167.955 202.217 107.048 1.00 26.85  ? 132 THR A CG2 1 
ATOM   624  N N   . ASN A 1 134 ? 166.244 205.603 109.521 1.00 25.68  ? 133 ASN A N   1 
ATOM   625  C CA  . ASN A 1 134 ? 165.270 206.430 110.242 1.00 26.25  ? 133 ASN A CA  1 
ATOM   626  C C   . ASN A 1 134 ? 163.913 205.715 110.296 1.00 26.91  ? 133 ASN A C   1 
ATOM   627  O O   . ASN A 1 134 ? 163.528 205.034 109.340 1.00 29.47  ? 133 ASN A O   1 
ATOM   628  C CB  . ASN A 1 134 ? 165.141 207.826 109.600 1.00 31.40  ? 133 ASN A CB  1 
ATOM   629  C CG  . ASN A 1 134 ? 166.356 208.779 109.883 1.00 34.40  ? 133 ASN A CG  1 
ATOM   630  O OD1 . ASN A 1 134 ? 167.152 208.536 110.818 1.00 32.82  ? 133 ASN A OD1 1 
ATOM   631  N ND2 . ASN A 1 134 ? 166.473 209.841 109.087 1.00 38.94  ? 133 ASN A ND2 1 
ATOM   632  N N   . VAL A 1 135 ? 163.182 205.891 111.419 1.00 27.80  ? 134 VAL A N   1 
ATOM   633  C CA  . VAL A 1 135 ? 161.870 205.290 111.660 1.00 30.02  ? 134 VAL A CA  1 
ATOM   634  C C   . VAL A 1 135 ? 160.782 205.958 110.829 1.00 33.20  ? 134 VAL A C   1 
ATOM   635  O O   . VAL A 1 135 ? 160.593 207.172 110.869 1.00 37.38  ? 134 VAL A O   1 
ATOM   636  C CB  . VAL A 1 135 ? 161.550 205.407 113.160 1.00 27.76  ? 134 VAL A CB  1 
ATOM   637  C CG1 . VAL A 1 135 ? 160.160 204.906 113.465 1.00 31.23  ? 134 VAL A CG1 1 
ATOM   638  C CG2 . VAL A 1 135 ? 162.550 204.630 113.935 1.00 22.55  ? 134 VAL A CG2 1 
ATOM   639  N N   . THR A 1 136 ? 160.036 205.145 110.099 1.00 34.09  ? 135 THR A N   1 
ATOM   640  C CA  . THR A 1 136 ? 158.992 205.609 109.204 1.00 38.24  ? 135 THR A CA  1 
ATOM   641  C C   . THR A 1 136 ? 157.685 205.867 109.907 1.00 41.34  ? 135 THR A C   1 
ATOM   642  O O   . THR A 1 136 ? 156.711 205.128 109.736 1.00 40.10  ? 135 THR A O   1 
ATOM   643  C CB  . THR A 1 136 ? 158.757 204.593 108.093 1.00 40.88  ? 135 THR A CB  1 
ATOM   644  O OG1 . THR A 1 136 ? 158.481 203.335 108.687 1.00 40.54  ? 135 THR A OG1 1 
ATOM   645  C CG2 . THR A 1 136 ? 160.005 204.484 107.230 1.00 42.93  ? 135 THR A CG2 1 
ATOM   646  N N   . ASN A 1 137 ? 157.680 206.913 110.711 1.00 41.63  ? 136 ASN A N   1 
ATOM   647  C CA  . ASN A 1 137 ? 156.514 207.294 111.493 1.00 41.73  ? 136 ASN A CA  1 
ATOM   648  C C   . ASN A 1 137 ? 156.476 208.826 111.633 1.00 42.36  ? 136 ASN A C   1 
ATOM   649  O O   . ASN A 1 137 ? 157.405 209.522 111.200 1.00 41.21  ? 136 ASN A O   1 
ATOM   650  C CB  . ASN A 1 137 ? 156.577 206.557 112.845 1.00 42.33  ? 136 ASN A CB  1 
ATOM   651  C CG  . ASN A 1 137 ? 155.243 206.403 113.584 1.00 39.33  ? 136 ASN A CG  1 
ATOM   652  O OD1 . ASN A 1 137 ? 154.299 207.142 113.280 1.00 41.20  ? 136 ASN A OD1 1 
ATOM   653  N ND2 . ASN A 1 137 ? 155.165 205.528 114.548 1.00 34.20  ? 136 ASN A ND2 1 
ATOM   654  N N   . ASN A 1 138 ? 155.438 209.366 112.304 1.00 44.34  ? 137 ASN A N   1 
ATOM   655  C CA  . ASN A 1 138 ? 155.274 210.799 112.529 1.00 52.82  ? 137 ASN A CA  1 
ATOM   656  C C   . ASN A 1 138 ? 155.985 211.193 113.827 1.00 48.77  ? 137 ASN A C   1 
ATOM   657  O O   . ASN A 1 138 ? 155.411 211.164 114.920 1.00 47.92  ? 137 ASN A O   1 
ATOM   658  C CB  . ASN A 1 138 ? 153.778 211.195 112.525 1.00 53.91  ? 137 ASN A CB  1 
ATOM   659  C CG  . ASN A 1 138 ? 153.231 211.550 111.092 1.00 63.73  ? 137 ASN A CG  1 
ATOM   660  O OD1 . ASN A 1 138 ? 153.992 212.065 110.248 1.00 78.16  ? 137 ASN A OD1 1 
ATOM   661  N ND2 . ASN A 1 138 ? 151.949 211.283 110.843 1.00 68.66  ? 137 ASN A ND2 1 
ATOM   662  N N   . ILE A 1 139 ? 157.269 211.545 113.661 1.00 50.44  ? 138 ILE A N   1 
ATOM   663  C CA  . ILE A 1 139 ? 158.205 211.917 114.713 1.00 38.77  ? 138 ILE A CA  1 
ATOM   664  C C   . ILE A 1 139 ? 158.256 213.413 114.819 1.00 45.30  ? 138 ILE A C   1 
ATOM   665  O O   . ILE A 1 139 ? 158.522 214.096 113.831 1.00 47.85  ? 138 ILE A O   1 
ATOM   666  C CB  . ILE A 1 139 ? 159.582 211.311 114.409 1.00 39.80  ? 138 ILE A CB  1 
ATOM   667  C CG1 . ILE A 1 139 ? 159.423 209.802 114.422 1.00 39.17  ? 138 ILE A CG1 1 
ATOM   668  C CG2 . ILE A 1 139 ? 160.576 211.741 115.420 1.00 41.94  ? 138 ILE A CG2 1 
ATOM   669  C CD1 . ILE A 1 139 ? 160.530 209.008 113.888 1.00 34.33  ? 138 ILE A CD1 1 
ATOM   670  N N   . THR A 1 140 ? 158.006 213.915 116.021 1.00 45.71  ? 139 THR A N   1 
ATOM   671  C CA  . THR A 1 140 ? 158.003 215.352 116.222 1.00 46.15  ? 139 THR A CA  1 
ATOM   672  C C   . THR A 1 140 ? 159.409 215.895 116.206 1.00 37.21  ? 139 THR A C   1 
ATOM   673  O O   . THR A 1 140 ? 160.374 215.151 116.332 1.00 40.38  ? 139 THR A O   1 
ATOM   674  C CB  . THR A 1 140 ? 157.322 215.729 117.538 1.00 48.09  ? 139 THR A CB  1 
ATOM   675  O OG1 . THR A 1 140 ? 157.195 217.157 117.595 1.00 39.88  ? 139 THR A OG1 1 
ATOM   676  C CG2 . THR A 1 140 ? 158.143 215.219 118.729 1.00 43.95  ? 139 THR A CG2 1 
ATOM   677  N N   . ASP A 1 141 ? 159.551 217.207 116.163 1.00 49.08  ? 140 ASP A N   1 
ATOM   678  C CA  . ASP A 1 141 ? 160.881 217.805 116.063 1.00 49.63  ? 140 ASP A CA  1 
ATOM   679  C C   . ASP A 1 141 ? 161.808 217.431 117.205 1.00 49.16  ? 140 ASP A C   1 
ATOM   680  O O   . ASP A 1 141 ? 162.983 217.127 116.989 1.00 46.85  ? 140 ASP A O   1 
ATOM   681  C CB  . ASP A 1 141 ? 160.756 219.315 116.014 1.00 61.42  ? 140 ASP A CB  1 
ATOM   682  C CG  . ASP A 1 141 ? 160.168 219.840 114.701 1.00 46.40  ? 140 ASP A CG  1 
ATOM   683  O OD1 . ASP A 1 141 ? 160.131 219.125 113.702 1.00 52.49  ? 140 ASP A OD1 1 
ATOM   684  O OD2 . ASP A 1 141 ? 159.740 220.962 114.714 1.00 59.64  ? 140 ASP A OD2 1 
ATOM   685  N N   . ASP A 1 142 ? 161.243 217.323 118.392 1.00 50.83  ? 141 ASP A N   1 
ATOM   686  C CA  . ASP A 1 142 ? 161.964 217.022 119.620 1.00 46.49  ? 141 ASP A CA  1 
ATOM   687  C C   . ASP A 1 142 ? 162.526 215.605 119.629 1.00 41.59  ? 141 ASP A C   1 
ATOM   688  O O   . ASP A 1 142 ? 163.390 215.278 120.442 1.00 33.21  ? 141 ASP A O   1 
ATOM   689  C CB  . ASP A 1 142 ? 161.021 217.167 120.806 1.00 43.88  ? 141 ASP A CB  1 
ATOM   690  C CG  . ASP A 1 142 ? 160.566 218.598 121.053 1.00 46.91  ? 141 ASP A CG  1 
ATOM   691  O OD1 . ASP A 1 142 ? 161.163 219.523 120.545 1.00 48.43  ? 141 ASP A OD1 1 
ATOM   692  O OD2 . ASP A 1 142 ? 159.579 218.748 121.726 1.00 46.93  ? 141 ASP A OD2 1 
ATOM   693  N N   . MET A 1 143 ? 161.966 214.744 118.791 1.00 40.35  ? 142 MET A N   1 
ATOM   694  C CA  . MET A 1 143 ? 162.354 213.357 118.685 1.00 35.62  ? 142 MET A CA  1 
ATOM   695  C C   . MET A 1 143 ? 163.098 213.010 117.411 1.00 37.19  ? 142 MET A C   1 
ATOM   696  O O   . MET A 1 143 ? 163.334 211.824 117.142 1.00 34.54  ? 142 MET A O   1 
ATOM   697  C CB  . MET A 1 143 ? 161.117 212.488 118.795 1.00 41.37  ? 142 MET A CB  1 
ATOM   698  C CG  . MET A 1 143 ? 160.520 212.438 120.134 1.00 32.56  ? 142 MET A CG  1 
ATOM   699  S SD  . MET A 1 143 ? 161.613 211.663 121.313 1.00 36.12  ? 142 MET A SD  1 
ATOM   700  C CE  . MET A 1 143 ? 161.566 209.925 120.848 1.00 29.46  ? 142 MET A CE  1 
ATOM   701  N N   . ARG A 1 144 ? 163.474 213.990 116.602 1.00 37.62  ? 143 ARG A N   1 
ATOM   702  C CA  . ARG A 1 144 ? 164.136 213.580 115.385 1.00 38.39  ? 143 ARG A CA  1 
ATOM   703  C C   . ARG A 1 144 ? 165.517 213.104 115.728 1.00 36.43  ? 143 ARG A C   1 
ATOM   704  O O   . ARG A 1 144 ? 166.247 213.764 116.461 1.00 33.63  ? 143 ARG A O   1 
ATOM   705  C CB  . ARG A 1 144 ? 164.202 214.702 114.382 1.00 42.88  ? 143 ARG A CB  1 
ATOM   706  C CG  . ARG A 1 144 ? 162.862 215.120 113.883 1.00 46.70  ? 143 ARG A CG  1 
ATOM   707  C CD  . ARG A 1 144 ? 162.944 216.193 112.883 1.00 42.10  ? 143 ARG A CD  1 
ATOM   708  N NE  . ARG A 1 144 ? 161.628 216.721 112.573 1.00 52.15  ? 143 ARG A NE  1 
ATOM   709  C CZ  . ARG A 1 144 ? 160.750 216.244 111.692 1.00 53.00  ? 143 ARG A CZ  1 
ATOM   710  N NH1 . ARG A 1 144 ? 160.994 215.167 110.959 1.00 60.80  ? 143 ARG A NH1 1 
ATOM   711  N NH2 . ARG A 1 144 ? 159.617 216.903 111.587 1.00 46.38  ? 143 ARG A NH2 1 
ATOM   712  N N   . GLY A 1 145 ? 165.872 211.939 115.218 1.00 32.50  ? 152 GLY A N   1 
ATOM   713  C CA  . GLY A 1 145 ? 167.182 211.366 115.463 1.00 32.33  ? 152 GLY A CA  1 
ATOM   714  C C   . GLY A 1 145 ? 167.246 210.531 116.742 1.00 29.32  ? 152 GLY A C   1 
ATOM   715  O O   . GLY A 1 145 ? 168.271 209.907 117.005 1.00 27.54  ? 152 GLY A O   1 
ATOM   716  N N   . GLU A 1 146 ? 166.157 210.494 117.522 1.00 30.44  ? 153 GLU A N   1 
ATOM   717  C CA  . GLU A 1 146 ? 166.143 209.742 118.771 1.00 28.46  ? 153 GLU A CA  1 
ATOM   718  C C   . GLU A 1 146 ? 165.985 208.249 118.593 1.00 22.40  ? 153 GLU A C   1 
ATOM   719  O O   . GLU A 1 146 ? 166.467 207.482 119.423 1.00 21.54  ? 153 GLU A O   1 
ATOM   720  C CB  . GLU A 1 146 ? 165.084 210.278 119.712 1.00 33.14  ? 153 GLU A CB  1 
ATOM   721  C CG  . GLU A 1 146 ? 165.413 211.651 120.252 1.00 35.33  ? 153 GLU A CG  1 
ATOM   722  C CD  . GLU A 1 146 ? 166.643 211.633 121.072 1.00 37.04  ? 153 GLU A CD  1 
ATOM   723  O OE1 . GLU A 1 146 ? 166.737 210.769 121.921 1.00 37.73  ? 153 GLU A OE1 1 
ATOM   724  O OE2 . GLU A 1 146 ? 167.511 212.453 120.855 1.00 40.91  ? 153 GLU A OE2 1 
ATOM   725  N N   . LEU A 1 147 ? 165.290 207.825 117.552 1.00 21.92  ? 154 LEU A N   1 
ATOM   726  C CA  . LEU A 1 147 ? 165.084 206.412 117.294 1.00 17.75  ? 154 LEU A CA  1 
ATOM   727  C C   . LEU A 1 147 ? 165.623 206.003 115.967 1.00 18.63  ? 154 LEU A C   1 
ATOM   728  O O   . LEU A 1 147 ? 165.527 206.737 114.980 1.00 20.49  ? 154 LEU A O   1 
ATOM   729  C CB  . LEU A 1 147 ? 163.612 206.034 117.285 1.00 18.17  ? 154 LEU A CB  1 
ATOM   730  C CG  . LEU A 1 147 ? 162.844 206.166 118.532 1.00 19.46  ? 154 LEU A CG  1 
ATOM   731  C CD1 . LEU A 1 147 ? 161.417 205.981 118.207 1.00 21.42  ? 154 LEU A CD1 1 
ATOM   732  C CD2 . LEU A 1 147 ? 163.273 205.075 119.502 1.00 17.20  ? 154 LEU A CD2 1 
ATOM   733  N N   . LYS A 1 148 ? 166.110 204.779 115.936 1.00 17.30  ? 155 LYS A N   1 
ATOM   734  C CA  . LYS A 1 148 ? 166.550 204.140 114.717 1.00 15.87  ? 155 LYS A CA  1 
ATOM   735  C C   . LYS A 1 148 ? 165.927 202.753 114.582 1.00 14.99  ? 155 LYS A C   1 
ATOM   736  O O   . LYS A 1 148 ? 165.764 202.030 115.572 1.00 15.56  ? 155 LYS A O   1 
ATOM   737  C CB  . LYS A 1 148 ? 168.063 204.010 114.690 1.00 15.66  ? 155 LYS A CB  1 
ATOM   738  C CG  . LYS A 1 148 ? 168.868 205.275 114.660 1.00 14.78  ? 155 LYS A CG  1 
ATOM   739  C CD  . LYS A 1 148 ? 168.790 205.953 113.319 1.00 19.27  ? 155 LYS A CD  1 
ATOM   740  C CE  . LYS A 1 148 ? 169.698 207.156 113.280 1.00 23.77  ? 155 LYS A CE  1 
ATOM   741  N NZ  . LYS A 1 148 ? 169.712 207.793 111.950 1.00 27.44  ? 155 LYS A NZ  1 
ATOM   742  N N   . ASN A 1 149 ? 165.588 202.380 113.335 1.00 17.77  ? 156 ASN A N   1 
ATOM   743  C CA  . ASN A 1 149 ? 165.041 201.092 112.923 1.00 16.42  ? 156 ASN A CA  1 
ATOM   744  C C   . ASN A 1 149 ? 166.194 200.214 112.419 1.00 16.95  ? 156 ASN A C   1 
ATOM   745  O O   . ASN A 1 149 ? 166.701 200.427 111.309 1.00 19.79  ? 156 ASN A O   1 
ATOM   746  C CB  . ASN A 1 149 ? 163.940 201.297 111.868 1.00 20.20  ? 156 ASN A CB  1 
ATOM   747  C CG  . ASN A 1 149 ? 162.995 200.099 111.672 1.00 22.27  ? 156 ASN A CG  1 
ATOM   748  O OD1 . ASN A 1 149 ? 162.882 199.219 112.545 1.00 21.93  ? 156 ASN A OD1 1 
ATOM   749  N ND2 . ASN A 1 149 ? 162.322 200.084 110.521 1.00 26.11  ? 156 ASN A ND2 1 
ATOM   750  N N   . CYS A 1 150 ? 166.674 199.270 113.268 1.00 16.70  ? 157 CYS A N   1 
ATOM   751  C CA  . CYS A 1 150 ? 167.896 198.490 113.033 1.00 15.07  ? 157 CYS A CA  1 
ATOM   752  C C   . CYS A 1 150 ? 167.653 197.024 112.728 1.00 14.96  ? 157 CYS A C   1 
ATOM   753  O O   . CYS A 1 150 ? 167.028 196.297 113.505 1.00 17.04  ? 157 CYS A O   1 
ATOM   754  C CB  . CYS A 1 150 ? 168.811 198.614 114.272 1.00 14.82  ? 157 CYS A CB  1 
ATOM   755  S SG  . CYS A 1 150 ? 169.363 200.325 114.694 1.00 14.03  ? 157 CYS A SG  1 
ATOM   756  N N   . SER A 1 151 ? 168.223 196.566 111.615 1.00 16.44  ? 158 SER A N   1 
ATOM   757  C CA  . SER A 1 151 ? 168.127 195.172 111.201 1.00 14.34  ? 158 SER A CA  1 
ATOM   758  C C   . SER A 1 151 ? 169.385 194.400 111.537 1.00 14.19  ? 158 SER A C   1 
ATOM   759  O O   . SER A 1 151 ? 170.496 194.917 111.421 1.00 16.11  ? 158 SER A O   1 
ATOM   760  C CB  . SER A 1 151 ? 167.904 195.081 109.711 1.00 15.66  ? 158 SER A CB  1 
ATOM   761  O OG  . SER A 1 151 ? 166.679 195.636 109.340 1.00 19.90  ? 158 SER A OG  1 
ATOM   762  N N   . PHE A 1 152 ? 169.230 193.144 111.928 1.00 15.20  ? 159 PHE A N   1 
ATOM   763  C CA  . PHE A 1 152 ? 170.376 192.290 112.194 1.00 13.75  ? 159 PHE A CA  1 
ATOM   764  C C   . PHE A 1 152 ? 170.077 190.791 112.065 1.00 14.04  ? 159 PHE A C   1 
ATOM   765  O O   . PHE A 1 152 ? 168.915 190.385 112.101 1.00 16.78  ? 159 PHE A O   1 
ATOM   766  C CB  . PHE A 1 152 ? 170.938 192.655 113.561 1.00 13.62  ? 159 PHE A CB  1 
ATOM   767  C CG  . PHE A 1 152 ? 170.000 192.498 114.714 1.00 12.52  ? 159 PHE A CG  1 
ATOM   768  C CD1 . PHE A 1 152 ? 169.128 193.522 115.043 1.00 13.05  ? 159 PHE A CD1 1 
ATOM   769  C CD2 . PHE A 1 152 ? 169.975 191.360 115.465 1.00 12.24  ? 159 PHE A CD2 1 
ATOM   770  C CE1 . PHE A 1 152 ? 168.269 193.407 116.079 1.00 12.47  ? 159 PHE A CE1 1 
ATOM   771  C CE2 . PHE A 1 152 ? 169.108 191.252 116.513 1.00 12.39  ? 159 PHE A CE2 1 
ATOM   772  C CZ  . PHE A 1 152 ? 168.261 192.269 116.820 1.00 12.33  ? 159 PHE A CZ  1 
ATOM   773  N N   . ASN A 1 153 ? 171.144 189.960 111.913 1.00 16.21  ? 160 ASN A N   1 
ATOM   774  C CA  . ASN A 1 153 ? 171.078 188.494 111.856 1.00 13.79  ? 160 ASN A CA  1 
ATOM   775  C C   . ASN A 1 153 ? 171.379 187.901 113.237 1.00 13.88  ? 160 ASN A C   1 
ATOM   776  O O   . ASN A 1 153 ? 172.531 187.892 113.680 1.00 16.03  ? 160 ASN A O   1 
ATOM   777  C CB  . ASN A 1 153 ? 172.046 187.924 110.811 1.00 17.12  ? 160 ASN A CB  1 
ATOM   778  C CG  . ASN A 1 153 ? 171.692 188.275 109.354 1.00 18.64  ? 160 ASN A CG  1 
ATOM   779  O OD1 . ASN A 1 153 ? 170.726 187.728 108.795 1.00 20.28  ? 160 ASN A OD1 1 
ATOM   780  N ND2 . ASN A 1 153 ? 172.479 189.162 108.750 1.00 24.97  ? 160 ASN A ND2 1 
ATOM   781  N N   . ALA A 1 154 ? 170.335 187.432 113.925 1.00 14.69  ? 161 ALA A N   1 
ATOM   782  C CA  . ALA A 1 154 ? 170.361 186.889 115.276 1.00 15.51  ? 161 ALA A CA  1 
ATOM   783  C C   . ALA A 1 154 ? 170.488 185.380 115.232 1.00 17.27  ? 161 ALA A C   1 
ATOM   784  O O   . ALA A 1 154 ? 170.091 184.728 114.264 1.00 19.29  ? 161 ALA A O   1 
ATOM   785  C CB  . ALA A 1 154 ? 169.105 187.286 116.025 1.00 16.12  ? 161 ALA A CB  1 
ATOM   786  N N   . THR A 1 155 ? 171.016 184.816 116.290 1.00 19.32  ? 162 THR A N   1 
ATOM   787  C CA  . THR A 1 155 ? 171.084 183.387 116.416 1.00 18.60  ? 162 THR A CA  1 
ATOM   788  C C   . THR A 1 155 ? 169.712 182.923 116.799 1.00 18.60  ? 162 THR A C   1 
ATOM   789  O O   . THR A 1 155 ? 168.859 183.764 117.088 1.00 20.87  ? 162 THR A O   1 
ATOM   790  C CB  . THR A 1 155 ? 172.158 182.992 117.435 1.00 19.37  ? 162 THR A CB  1 
ATOM   791  O OG1 . THR A 1 155 ? 171.854 183.553 118.717 1.00 18.38  ? 162 THR A OG1 1 
ATOM   792  C CG2 . THR A 1 155 ? 173.490 183.530 116.971 1.00 24.58  ? 162 THR A CG2 1 
ATOM   793  N N   . THR A 1 156 ? 169.482 181.621 116.724 1.00 19.28  ? 163 THR A N   1 
ATOM   794  C CA  . THR A 1 156 ? 168.215 181.006 117.074 1.00 18.82  ? 163 THR A CA  1 
ATOM   795  C C   . THR A 1 156 ? 168.560 179.903 118.045 1.00 18.85  ? 163 THR A C   1 
ATOM   796  O O   . THR A 1 156 ? 169.721 179.745 118.427 1.00 20.54  ? 163 THR A O   1 
ATOM   797  C CB  . THR A 1 156 ? 167.465 180.374 115.889 1.00 20.05  ? 163 THR A CB  1 
ATOM   798  O OG1 . THR A 1 156 ? 168.092 179.176 115.522 1.00 23.67  ? 163 THR A OG1 1 
ATOM   799  C CG2 . THR A 1 156 ? 167.533 181.295 114.692 1.00 19.02  ? 163 THR A CG2 1 
ATOM   800  N N   . GLU A 1 157 ? 167.570 179.130 118.448 1.00 20.76  ? 164 GLU A N   1 
ATOM   801  C CA  . GLU A 1 157 ? 167.788 178.021 119.362 1.00 21.83  ? 164 GLU A CA  1 
ATOM   802  C C   . GLU A 1 157 ? 168.662 176.896 118.759 1.00 20.75  ? 164 GLU A C   1 
ATOM   803  O O   . GLU A 1 157 ? 169.160 176.045 119.496 1.00 20.52  ? 164 GLU A O   1 
ATOM   804  C CB  . GLU A 1 157 ? 166.445 177.492 119.886 1.00 23.92  ? 164 GLU A CB  1 
ATOM   805  C CG  . GLU A 1 157 ? 165.484 176.888 118.853 1.00 27.07  ? 164 GLU A CG  1 
ATOM   806  C CD  . GLU A 1 157 ? 164.575 177.911 118.187 1.00 32.69  ? 164 GLU A CD  1 
ATOM   807  O OE1 . GLU A 1 157 ? 164.910 179.077 118.206 1.00 27.60  ? 164 GLU A OE1 1 
ATOM   808  O OE2 . GLU A 1 157 ? 163.566 177.525 117.661 1.00 46.45  ? 164 GLU A OE2 1 
ATOM   809  N N   . LEU A 1 158 ? 168.845 176.877 117.428 1.00 21.74  ? 165 LEU A N   1 
ATOM   810  C CA  . LEU A 1 158 ? 169.724 175.891 116.802 1.00 18.41  ? 165 LEU A CA  1 
ATOM   811  C C   . LEU A 1 158 ? 170.964 176.601 116.274 1.00 17.82  ? 165 LEU A C   1 
ATOM   812  O O   . LEU A 1 158 ? 170.890 177.655 115.651 1.00 24.04  ? 165 LEU A O   1 
ATOM   813  C CB  . LEU A 1 158 ? 169.033 175.104 115.692 1.00 19.06  ? 165 LEU A CB  1 
ATOM   814  C CG  . LEU A 1 158 ? 167.792 174.287 116.099 1.00 18.91  ? 165 LEU A CG  1 
ATOM   815  C CD1 . LEU A 1 158 ? 167.251 173.643 114.898 1.00 17.88  ? 165 LEU A CD1 1 
ATOM   816  C CD2 . LEU A 1 158 ? 168.140 173.213 117.142 1.00 18.64  ? 165 LEU A CD2 1 
ATOM   817  N N   . ARG A 1 159 ? 172.107 175.975 116.448 1.00 18.13  ? 166 ARG A N   1 
ATOM   818  C CA  . ARG A 1 159 ? 173.388 176.570 116.092 1.00 19.83  ? 166 ARG A CA  1 
ATOM   819  C C   . ARG A 1 159 ? 173.638 176.819 114.625 1.00 20.76  ? 166 ARG A C   1 
ATOM   820  O O   . ARG A 1 159 ? 174.465 177.661 114.264 1.00 24.01  ? 166 ARG A O   1 
ATOM   821  C CB  . ARG A 1 159 ? 174.497 175.710 116.619 1.00 20.82  ? 166 ARG A CB  1 
ATOM   822  C CG  . ARG A 1 159 ? 174.622 175.736 118.082 1.00 20.32  ? 166 ARG A CG  1 
ATOM   823  C CD  . ARG A 1 159 ? 175.581 174.778 118.537 1.00 23.15  ? 166 ARG A CD  1 
ATOM   824  N NE  . ARG A 1 159 ? 176.923 175.050 118.068 1.00 24.33  ? 166 ARG A NE  1 
ATOM   825  C CZ  . ARG A 1 159 ? 177.802 175.879 118.668 1.00 28.15  ? 166 ARG A CZ  1 
ATOM   826  N NH1 . ARG A 1 159 ? 177.470 176.537 119.763 1.00 26.39  ? 166 ARG A NH1 1 
ATOM   827  N NH2 . ARG A 1 159 ? 179.006 176.034 118.155 1.00 33.79  ? 166 ARG A NH2 1 
ATOM   828  N N   . ASN A 1 160 ? 172.969 176.085 113.763 1.00 21.86  ? 167 ASN A N   1 
ATOM   829  C CA  . ASN A 1 160 ? 173.189 176.253 112.351 1.00 22.67  ? 167 ASN A CA  1 
ATOM   830  C C   . ASN A 1 160 ? 172.117 177.084 111.665 1.00 22.94  ? 167 ASN A C   1 
ATOM   831  O O   . ASN A 1 160 ? 172.038 177.095 110.437 1.00 24.69  ? 167 ASN A O   1 
ATOM   832  C CB  . ASN A 1 160 ? 173.393 174.892 111.715 1.00 25.83  ? 167 ASN A CB  1 
ATOM   833  C CG  . ASN A 1 160 ? 172.212 173.962 111.828 1.00 22.45  ? 167 ASN A CG  1 
ATOM   834  O OD1 . ASN A 1 160 ? 171.393 174.058 112.754 1.00 20.38  ? 167 ASN A OD1 1 
ATOM   835  N ND2 . ASN A 1 160 ? 172.133 173.046 110.893 1.00 23.51  ? 167 ASN A ND2 1 
ATOM   836  N N   . LYS A 1 161 ? 171.319 177.812 112.449 1.00 23.41  ? 168 LYS A N   1 
ATOM   837  C CA  . LYS A 1 161 ? 170.263 178.651 111.909 1.00 21.48  ? 168 LYS A CA  1 
ATOM   838  C C   . LYS A 1 161 ? 170.420 180.104 112.339 1.00 22.56  ? 168 LYS A C   1 
ATOM   839  O O   . LYS A 1 161 ? 170.966 180.398 113.403 1.00 22.87  ? 168 LYS A O   1 
ATOM   840  C CB  . LYS A 1 161 ? 168.913 178.113 112.358 1.00 22.17  ? 168 LYS A CB  1 
ATOM   841  C CG  . LYS A 1 161 ? 168.605 176.679 111.939 1.00 22.85  ? 168 LYS A CG  1 
ATOM   842  C CD  . LYS A 1 161 ? 168.402 176.546 110.447 1.00 26.34  ? 168 LYS A CD  1 
ATOM   843  C CE  . LYS A 1 161 ? 168.050 175.136 110.070 1.00 28.61  ? 168 LYS A CE  1 
ATOM   844  N NZ  . LYS A 1 161 ? 167.858 174.979 108.596 1.00 35.92  ? 168 LYS A NZ  1 
ATOM   845  N N   . ARG A 1 162 ? 169.923 181.016 111.510 1.00 22.89  ? 169 ARG A N   1 
ATOM   846  C CA  . ARG A 1 162 ? 169.922 182.446 111.809 1.00 20.49  ? 169 ARG A CA  1 
ATOM   847  C C   . ARG A 1 162 ? 168.565 183.016 111.479 1.00 19.59  ? 169 ARG A C   1 
ATOM   848  O O   . ARG A 1 162 ? 167.848 182.467 110.641 1.00 21.08  ? 169 ARG A O   1 
ATOM   849  C CB  . ARG A 1 162 ? 170.977 183.199 111.005 1.00 22.44  ? 169 ARG A CB  1 
ATOM   850  C CG  . ARG A 1 162 ? 172.418 182.792 111.277 1.00 28.69  ? 169 ARG A CG  1 
ATOM   851  C CD  . ARG A 1 162 ? 172.883 183.203 112.618 1.00 27.10  ? 169 ARG A CD  1 
ATOM   852  N NE  . ARG A 1 162 ? 174.272 182.867 112.828 1.00 31.77  ? 169 ARG A NE  1 
ATOM   853  C CZ  . ARG A 1 162 ? 174.726 181.672 113.295 1.00 34.58  ? 169 ARG A CZ  1 
ATOM   854  N NH1 . ARG A 1 162 ? 173.898 180.676 113.595 1.00 28.42  ? 169 ARG A NH1 1 
ATOM   855  N NH2 . ARG A 1 162 ? 176.025 181.498 113.452 1.00 40.58  ? 169 ARG A NH2 1 
ATOM   856  N N   . GLN A 1 163 ? 168.219 184.122 112.116 1.00 18.73  ? 170 GLN A N   1 
ATOM   857  C CA  . GLN A 1 163 ? 166.962 184.785 111.825 1.00 17.70  ? 170 GLN A CA  1 
ATOM   858  C C   . GLN A 1 163 ? 167.173 186.270 111.623 1.00 16.68  ? 170 GLN A C   1 
ATOM   859  O O   . GLN A 1 163 ? 168.013 186.885 112.277 1.00 18.78  ? 170 GLN A O   1 
ATOM   860  C CB  . GLN A 1 163 ? 165.966 184.514 112.969 1.00 18.32  ? 170 GLN A CB  1 
ATOM   861  C CG  . GLN A 1 163 ? 166.418 185.010 114.341 1.00 16.68  ? 170 GLN A CG  1 
ATOM   862  C CD  . GLN A 1 163 ? 165.485 184.631 115.489 1.00 16.93  ? 170 GLN A CD  1 
ATOM   863  O OE1 . GLN A 1 163 ? 164.259 184.723 115.392 1.00 20.98  ? 170 GLN A OE1 1 
ATOM   864  N NE2 . GLN A 1 163 ? 166.077 184.188 116.587 1.00 16.20  ? 170 GLN A NE2 1 
ATOM   865  N N   . LYS A 1 164 ? 166.377 186.863 110.743 1.00 18.90  ? 171 LYS A N   1 
ATOM   866  C CA  . LYS A 1 164 ? 166.473 188.295 110.519 1.00 17.99  ? 171 LYS A CA  1 
ATOM   867  C C   . LYS A 1 164 ? 165.487 188.998 111.422 1.00 19.67  ? 171 LYS A C   1 
ATOM   868  O O   . LYS A 1 164 ? 164.292 188.699 111.418 1.00 20.53  ? 171 LYS A O   1 
ATOM   869  C CB  . LYS A 1 164 ? 166.252 188.642 109.059 1.00 21.63  ? 171 LYS A CB  1 
ATOM   870  C CG  . LYS A 1 164 ? 166.470 190.103 108.731 1.00 23.05  ? 171 LYS A CG  1 
ATOM   871  C CD  . LYS A 1 164 ? 166.304 190.344 107.241 1.00 31.05  ? 171 LYS A CD  1 
ATOM   872  C CE  . LYS A 1 164 ? 166.499 191.799 106.878 1.00 35.84  ? 171 LYS A CE  1 
ATOM   873  N NZ  . LYS A 1 164 ? 166.321 192.030 105.415 1.00 35.15  ? 171 LYS A NZ  1 
ATOM   874  N N   . VAL A 1 165 ? 166.010 189.917 112.206 1.00 19.11  ? 172 VAL A N   1 
ATOM   875  C CA  . VAL A 1 165 ? 165.271 190.637 113.208 1.00 17.47  ? 172 VAL A CA  1 
ATOM   876  C C   . VAL A 1 165 ? 165.414 192.118 113.041 1.00 17.14  ? 172 VAL A C   1 
ATOM   877  O O   . VAL A 1 165 ? 166.495 192.605 112.732 1.00 17.36  ? 172 VAL A O   1 
ATOM   878  C CB  . VAL A 1 165 ? 165.834 190.263 114.588 1.00 15.87  ? 172 VAL A CB  1 
ATOM   879  C CG1 . VAL A 1 165 ? 165.096 190.998 115.740 1.00 15.18  ? 172 VAL A CG1 1 
ATOM   880  C CG2 . VAL A 1 165 ? 165.777 188.791 114.738 1.00 17.06  ? 172 VAL A CG2 1 
ATOM   881  N N   . TYR A 1 166 ? 164.337 192.857 113.198 1.00 20.44  ? 173 TYR A N   1 
ATOM   882  C CA  . TYR A 1 166 ? 164.520 194.286 113.207 1.00 18.98  ? 173 TYR A CA  1 
ATOM   883  C C   . TYR A 1 166 ? 163.910 194.759 114.489 1.00 18.07  ? 173 TYR A C   1 
ATOM   884  O O   . TYR A 1 166 ? 162.950 194.167 114.981 1.00 19.89  ? 173 TYR A O   1 
ATOM   885  C CB  . TYR A 1 166 ? 163.908 195.000 112.005 1.00 21.17  ? 173 TYR A CB  1 
ATOM   886  C CG  . TYR A 1 166 ? 162.446 194.906 111.933 1.00 26.66  ? 173 TYR A CG  1 
ATOM   887  C CD1 . TYR A 1 166 ? 161.663 195.844 112.590 1.00 28.49  ? 173 TYR A CD1 1 
ATOM   888  C CD2 . TYR A 1 166 ? 161.860 193.895 111.207 1.00 29.86  ? 173 TYR A CD2 1 
ATOM   889  C CE1 . TYR A 1 166 ? 160.296 195.759 112.529 1.00 30.11  ? 173 TYR A CE1 1 
ATOM   890  C CE2 . TYR A 1 166 ? 160.494 193.814 111.141 1.00 33.09  ? 173 TYR A CE2 1 
ATOM   891  C CZ  . TYR A 1 166 ? 159.713 194.737 111.797 1.00 33.73  ? 173 TYR A CZ  1 
ATOM   892  O OH  . TYR A 1 166 ? 158.346 194.641 111.733 1.00 37.37  ? 173 TYR A OH  1 
ATOM   893  N N   . SER A 1 167 ? 164.446 195.830 115.018 1.00 18.61  ? 174 SER A N   1 
ATOM   894  C CA  . SER A 1 167 ? 163.935 196.401 116.244 1.00 15.06  ? 174 SER A CA  1 
ATOM   895  C C   . SER A 1 167 ? 164.226 197.872 116.348 1.00 14.03  ? 174 SER A C   1 
ATOM   896  O O   . SER A 1 167 ? 165.072 198.409 115.625 1.00 15.51  ? 174 SER A O   1 
ATOM   897  C CB  . SER A 1 167 ? 164.544 195.680 117.411 1.00 12.98  ? 174 SER A CB  1 
ATOM   898  O OG  . SER A 1 167 ? 165.901 195.900 117.478 1.00 13.92  ? 174 SER A OG  1 
ATOM   899  N N   . LEU A 1 168 ? 163.532 198.540 117.254 1.00 15.19  ? 175 LEU A N   1 
ATOM   900  C CA  . LEU A 1 168 ? 163.816 199.936 117.478 1.00 13.14  ? 175 LEU A CA  1 
ATOM   901  C C   . LEU A 1 168 ? 164.749 200.132 118.632 1.00 12.59  ? 175 LEU A C   1 
ATOM   902  O O   . LEU A 1 168 ? 164.549 199.586 119.716 1.00 13.31  ? 175 LEU A O   1 
ATOM   903  C CB  . LEU A 1 168 ? 162.529 200.715 117.760 1.00 14.98  ? 175 LEU A CB  1 
ATOM   904  C CG  . LEU A 1 168 ? 161.488 200.777 116.662 1.00 15.91  ? 175 LEU A CG  1 
ATOM   905  C CD1 . LEU A 1 168 ? 160.287 201.494 117.193 1.00 19.26  ? 175 LEU A CD1 1 
ATOM   906  C CD2 . LEU A 1 168 ? 162.054 201.514 115.494 1.00 17.39  ? 175 LEU A CD2 1 
ATOM   907  N N   . PHE A 1 169 ? 165.741 200.965 118.410 1.00 12.81  ? 176 PHE A N   1 
ATOM   908  C CA  . PHE A 1 169 ? 166.689 201.308 119.441 1.00 12.95  ? 176 PHE A CA  1 
ATOM   909  C C   . PHE A 1 169 ? 166.741 202.788 119.629 1.00 14.04  ? 176 PHE A C   1 
ATOM   910  O O   . PHE A 1 169 ? 166.550 203.565 118.691 1.00 16.43  ? 176 PHE A O   1 
ATOM   911  C CB  . PHE A 1 169 ? 168.112 200.834 119.143 1.00 12.87  ? 176 PHE A CB  1 
ATOM   912  C CG  . PHE A 1 169 ? 168.328 199.359 119.110 1.00 12.72  ? 176 PHE A CG  1 
ATOM   913  C CD1 . PHE A 1 169 ? 168.501 198.637 120.264 1.00 13.74  ? 176 PHE A CD1 1 
ATOM   914  C CD2 . PHE A 1 169 ? 168.361 198.703 117.939 1.00 12.44  ? 176 PHE A CD2 1 
ATOM   915  C CE1 . PHE A 1 169 ? 168.703 197.282 120.219 1.00 12.30  ? 176 PHE A CE1 1 
ATOM   916  C CE2 . PHE A 1 169 ? 168.570 197.353 117.879 1.00 11.06  ? 176 PHE A CE2 1 
ATOM   917  C CZ  . PHE A 1 169 ? 168.741 196.643 119.017 1.00 10.34  ? 176 PHE A CZ  1 
ATOM   918  N N   . TYR A 1 170 ? 167.053 203.192 120.836 1.00 14.59  ? 177 TYR A N   1 
ATOM   919  C CA  . TYR A 1 170 ? 167.259 204.589 121.074 1.00 14.29  ? 177 TYR A CA  1 
ATOM   920  C C   . TYR A 1 170 ? 168.632 204.894 120.558 1.00 13.81  ? 177 TYR A C   1 
ATOM   921  O O   . TYR A 1 170 ? 169.554 204.101 120.699 1.00 16.36  ? 177 TYR A O   1 
ATOM   922  C CB  . TYR A 1 170 ? 167.129 204.939 122.549 1.00 14.41  ? 177 TYR A CB  1 
ATOM   923  C CG  . TYR A 1 170 ? 165.736 204.825 123.064 1.00 13.29  ? 177 TYR A CG  1 
ATOM   924  C CD1 . TYR A 1 170 ? 164.790 205.755 122.716 1.00 13.49  ? 177 TYR A CD1 1 
ATOM   925  C CD2 . TYR A 1 170 ? 165.407 203.784 123.869 1.00 13.64  ? 177 TYR A CD2 1 
ATOM   926  C CE1 . TYR A 1 170 ? 163.515 205.626 123.179 1.00 13.44  ? 177 TYR A CE1 1 
ATOM   927  C CE2 . TYR A 1 170 ? 164.138 203.652 124.334 1.00 13.73  ? 177 TYR A CE2 1 
ATOM   928  C CZ  . TYR A 1 170 ? 163.187 204.573 123.984 1.00 13.71  ? 177 TYR A CZ  1 
ATOM   929  O OH  . TYR A 1 170 ? 161.901 204.428 124.447 1.00 17.07  ? 177 TYR A OH  1 
ATOM   930  N N   . ARG A 1 171 ? 168.812 206.068 120.025 1.00 16.27  ? 178 ARG A N   1 
ATOM   931  C CA  . ARG A 1 171 ? 170.093 206.461 119.496 1.00 15.50  ? 178 ARG A CA  1 
ATOM   932  C C   . ARG A 1 171 ? 171.190 206.430 120.547 1.00 15.75  ? 178 ARG A C   1 
ATOM   933  O O   . ARG A 1 171 ? 172.337 206.145 120.225 1.00 18.33  ? 178 ARG A O   1 
ATOM   934  C CB  . ARG A 1 171 ? 169.991 207.810 118.835 1.00 18.84  ? 178 ARG A CB  1 
ATOM   935  C CG  . ARG A 1 171 ? 171.275 208.372 118.263 1.00 19.24  ? 178 ARG A CG  1 
ATOM   936  C CD  . ARG A 1 171 ? 171.835 207.543 117.157 1.00 17.43  ? 178 ARG A CD  1 
ATOM   937  N NE  . ARG A 1 171 ? 173.057 208.113 116.653 1.00 18.37  ? 178 ARG A NE  1 
ATOM   938  C CZ  . ARG A 1 171 ? 174.276 207.970 117.209 1.00 17.83  ? 178 ARG A CZ  1 
ATOM   939  N NH1 . ARG A 1 171 ? 174.448 207.257 118.307 1.00 18.05  ? 178 ARG A NH1 1 
ATOM   940  N NH2 . ARG A 1 171 ? 175.308 208.576 116.649 1.00 18.56  ? 178 ARG A NH2 1 
ATOM   941  N N   . LEU A 1 172 ? 170.854 206.668 121.809 1.00 16.34  ? 179 LEU A N   1 
ATOM   942  C CA  . LEU A 1 172 ? 171.845 206.673 122.876 1.00 16.40  ? 179 LEU A CA  1 
ATOM   943  C C   . LEU A 1 172 ? 172.460 205.301 123.136 1.00 16.29  ? 179 LEU A C   1 
ATOM   944  O O   . LEU A 1 172 ? 173.484 205.205 123.810 1.00 17.79  ? 179 LEU A O   1 
ATOM   945  C CB  . LEU A 1 172 ? 171.210 207.124 124.194 1.00 17.37  ? 179 LEU A CB  1 
ATOM   946  C CG  . LEU A 1 172 ? 170.731 208.567 124.335 1.00 17.20  ? 179 LEU A CG  1 
ATOM   947  C CD1 . LEU A 1 172 ? 169.988 208.683 125.632 1.00 15.91  ? 179 LEU A CD1 1 
ATOM   948  C CD2 . LEU A 1 172 ? 171.904 209.520 124.351 1.00 17.90  ? 179 LEU A CD2 1 
ATOM   949  N N   . ASP A 1 173 ? 171.806 204.239 122.677 1.00 16.02  ? 180 ASP A N   1 
ATOM   950  C CA  . ASP A 1 173 ? 172.268 202.883 122.893 1.00 14.39  ? 180 ASP A CA  1 
ATOM   951  C C   . ASP A 1 173 ? 173.108 202.316 121.756 1.00 13.91  ? 180 ASP A C   1 
ATOM   952  O O   . ASP A 1 173 ? 173.569 201.174 121.854 1.00 14.94  ? 180 ASP A O   1 
ATOM   953  C CB  . ASP A 1 173 ? 171.063 201.983 123.105 1.00 14.41  ? 180 ASP A CB  1 
ATOM   954  C CG  . ASP A 1 173 ? 170.316 202.252 124.414 1.00 16.73  ? 180 ASP A CG  1 
ATOM   955  O OD1 . ASP A 1 173 ? 170.909 202.550 125.419 1.00 16.75  ? 180 ASP A OD1 1 
ATOM   956  O OD2 . ASP A 1 173 ? 169.129 202.154 124.425 1.00 16.59  ? 180 ASP A OD2 1 
ATOM   957  N N   . ILE A 1 174 ? 173.283 203.066 120.666 1.00 16.08  ? 181 ILE A N   1 
ATOM   958  C CA  . ILE A 1 174 ? 174.034 202.558 119.522 1.00 14.01  ? 181 ILE A CA  1 
ATOM   959  C C   . ILE A 1 174 ? 175.116 203.534 119.086 1.00 14.84  ? 181 ILE A C   1 
ATOM   960  O O   . ILE A 1 174 ? 175.056 204.724 119.374 1.00 17.76  ? 181 ILE A O   1 
ATOM   961  C CB  . ILE A 1 174 ? 173.083 202.168 118.355 1.00 13.45  ? 181 ILE A CB  1 
ATOM   962  C CG1 . ILE A 1 174 ? 172.308 203.365 117.887 1.00 14.28  ? 181 ILE A CG1 1 
ATOM   963  C CG2 . ILE A 1 174 ? 172.158 201.028 118.776 1.00 12.65  ? 181 ILE A CG2 1 
ATOM   964  C CD1 . ILE A 1 174 ? 171.474 203.158 116.662 1.00 13.86  ? 181 ILE A CD1 1 
ATOM   965  N N   . VAL A 1 175 ? 176.113 203.028 118.390 1.00 16.13  ? 182 VAL A N   1 
ATOM   966  C CA  . VAL A 1 175 ? 177.175 203.873 117.885 1.00 17.00  ? 182 VAL A CA  1 
ATOM   967  C C   . VAL A 1 175 ? 177.567 203.493 116.447 1.00 18.44  ? 182 VAL A C   1 
ATOM   968  O O   . VAL A 1 175 ? 177.650 202.305 116.156 1.00 22.47  ? 182 VAL A O   1 
ATOM   969  C CB  . VAL A 1 175 ? 178.343 203.783 118.877 1.00 18.74  ? 182 VAL A CB  1 
ATOM   970  C CG1 . VAL A 1 175 ? 178.783 202.406 119.021 1.00 18.32  ? 182 VAL A CG1 1 
ATOM   971  C CG2 . VAL A 1 175 ? 179.494 204.626 118.453 1.00 23.04  ? 182 VAL A CG2 1 
ATOM   972  N N   . PRO A 1 176 ? 177.770 204.448 115.518 1.00 19.47  ? 183 PRO A N   1 
ATOM   973  C CA  . PRO A 1 176 ? 178.222 204.236 114.154 1.00 21.63  ? 183 PRO A CA  1 
ATOM   974  C C   . PRO A 1 176 ? 179.588 203.607 114.103 1.00 26.87  ? 183 PRO A C   1 
ATOM   975  O O   . PRO A 1 176 ? 180.443 203.929 114.928 1.00 26.35  ? 183 PRO A O   1 
ATOM   976  C CB  . PRO A 1 176 ? 178.339 205.655 113.610 1.00 25.18  ? 183 PRO A CB  1 
ATOM   977  C CG  . PRO A 1 176 ? 177.445 206.465 114.431 1.00 20.79  ? 183 PRO A CG  1 
ATOM   978  C CD  . PRO A 1 176 ? 177.463 205.840 115.796 1.00 19.77  ? 183 PRO A CD  1 
ATOM   979  N N   . MET A 1 177 ? 179.834 202.775 113.110 1.00 27.59  ? 184 MET A N   1 
ATOM   980  C CA  . MET A 1 177 ? 181.162 202.215 112.942 1.00 30.87  ? 184 MET A CA  1 
ATOM   981  C C   . MET A 1 177 ? 181.844 202.790 111.723 1.00 38.42  ? 184 MET A C   1 
ATOM   982  O O   . MET A 1 177 ? 181.298 202.770 110.624 1.00 38.83  ? 184 MET A O   1 
ATOM   983  C CB  . MET A 1 177 ? 181.094 200.730 112.755 1.00 29.45  ? 184 MET A CB  1 
ATOM   984  C CG  . MET A 1 177 ? 180.517 199.991 113.898 1.00 23.15  ? 184 MET A CG  1 
ATOM   985  S SD  . MET A 1 177 ? 180.368 198.274 113.560 1.00 22.28  ? 184 MET A SD  1 
ATOM   986  C CE  . MET A 1 177 ? 179.006 198.332 112.456 1.00 22.16  ? 184 MET A CE  1 
ATOM   987  N N   . GLY A 1 178 ? 183.027 203.361 111.907 1.00 42.60  ? 185 GLY A N   1 
ATOM   988  C CA  . GLY A 1 178 ? 183.767 203.906 110.766 1.00 50.21  ? 185 GLY A CA  1 
ATOM   989  C C   . GLY A 1 178 ? 183.099 205.160 110.224 1.00 51.33  ? 185 GLY A C   1 
ATOM   990  O O   . GLY A 1 178 ? 183.283 205.521 109.063 1.00 54.64  ? 185 GLY A O   1 
ATOM   991  N N   . GLU A 1 179 ? 182.285 205.786 111.069 1.00 50.53  ? 186 GLU A N   1 
ATOM   992  C CA  . GLU A 1 179 ? 181.466 206.948 110.746 1.00 55.59  ? 186 GLU A CA  1 
ATOM   993  C C   . GLU A 1 179 ? 180.431 206.622 109.661 1.00 51.86  ? 186 GLU A C   1 
ATOM   994  O O   . GLU A 1 179 ? 179.906 207.527 109.008 1.00 54.43  ? 186 GLU A O   1 
ATOM   995  C CB  . GLU A 1 179 ? 182.333 208.126 110.263 1.00 64.73  ? 186 GLU A CB  1 
ATOM   996  C CG  . GLU A 1 179 ? 183.382 208.626 111.261 1.00 70.48  ? 186 GLU A CG  1 
ATOM   997  C CD  . GLU A 1 179 ? 184.171 209.806 110.725 1.00 74.32  ? 186 GLU A CD  1 
ATOM   998  O OE1 . GLU A 1 179 ? 184.112 210.032 109.541 1.00 76.71  ? 186 GLU A OE1 1 
ATOM   999  O OE2 . GLU A 1 179 ? 184.826 210.469 111.495 1.00 81.40  ? 186 GLU A OE2 1 
ATOM   1000 N N   . ASN A 1 180 ? 180.065 205.325 109.531 1.00 44.93  ? 187 ASN A N   1 
ATOM   1001 C CA  . ASN A 1 180 ? 179.088 204.873 108.481 1.00 44.84  ? 187 ASN A CA  1 
ATOM   1002 C C   . ASN A 1 180 ? 177.641 205.062 108.933 1.00 42.94  ? 187 ASN A C   1 
ATOM   1003 O O   . ASN A 1 180 ? 177.344 204.733 110.093 1.00 36.15  ? 187 ASN A O   1 
ATOM   1004 C CB  . ASN A 1 180 ? 179.275 203.437 107.983 1.00 44.00  ? 187 ASN A CB  1 
ATOM   1005 C CG  . ASN A 1 180 ? 178.433 203.134 106.761 1.00 39.27  ? 187 ASN A CG  1 
ATOM   1006 O OD1 . ASN A 1 180 ? 178.001 204.042 106.059 1.00 37.14  ? 187 ASN A OD1 1 
ATOM   1007 N ND2 . ASN A 1 180 ? 178.205 201.861 106.489 1.00 43.26  ? 187 ASN A ND2 1 
ATOM   1008 N N   . SER A 1 181 ? 176.776 205.548 108.040 1.00 43.41  ? 188 SER A N   1 
ATOM   1009 C CA  . SER A 1 181 ? 175.394 205.925 108.437 1.00 40.29  ? 188 SER A CA  1 
ATOM   1010 C C   . SER A 1 181 ? 174.403 204.788 108.260 1.00 37.34  ? 188 SER A C   1 
ATOM   1011 O O   . SER A 1 181 ? 173.193 205.032 108.389 1.00 32.98  ? 188 SER A O   1 
ATOM   1012 C CB  . SER A 1 181 ? 174.929 207.162 107.731 1.00 46.28  ? 188 SER A CB  1 
ATOM   1013 O OG  . SER A 1 181 ? 174.380 206.859 106.456 1.00 45.27  ? 188 SER A OG  1 
ATOM   1014 N N   . THR A 1 182 ? 174.873 203.616 107.882 1.00 34.92  ? 189 THR A N   1 
ATOM   1015 C CA  . THR A 1 182 ? 173.903 202.511 107.894 1.00 30.04  ? 189 THR A CA  1 
ATOM   1016 C C   . THR A 1 182 ? 174.375 201.498 108.932 1.00 26.31  ? 189 THR A C   1 
ATOM   1017 O O   . THR A 1 182 ? 173.522 200.827 109.491 1.00 26.79  ? 189 THR A O   1 
ATOM   1018 C CB  . THR A 1 182 ? 173.706 201.975 106.478 1.00 30.00  ? 189 THR A CB  1 
ATOM   1019 O OG1 . THR A 1 182 ? 174.620 202.715 105.669 1.00 30.00  ? 189 THR A OG1 1 
ATOM   1020 C CG2 . THR A 1 182 ? 172.291 202.142 105.972 1.00 30.00  ? 189 THR A CG2 1 
ATOM   1021 N N   . ASN A 1 183 ? 175.682 201.438 109.210 1.00 30.48  ? 190 ASN A N   1 
ATOM   1022 C CA  . ASN A 1 183 ? 176.187 200.360 110.093 1.00 24.67  ? 190 ASN A CA  1 
ATOM   1023 C C   . ASN A 1 183 ? 176.500 200.870 111.490 1.00 22.51  ? 190 ASN A C   1 
ATOM   1024 O O   . ASN A 1 183 ? 177.399 201.696 111.634 1.00 27.11  ? 190 ASN A O   1 
ATOM   1025 C CB  . ASN A 1 183 ? 177.363 199.611 109.488 1.00 29.30  ? 190 ASN A CB  1 
ATOM   1026 C CG  . ASN A 1 183 ? 177.108 198.981 108.137 1.00 29.41  ? 190 ASN A CG  1 
ATOM   1027 O OD1 . ASN A 1 183 ? 175.972 198.868 107.687 1.00 29.24  ? 190 ASN A OD1 1 
ATOM   1028 N ND2 . ASN A 1 183 ? 178.174 198.561 107.481 1.00 34.14  ? 190 ASN A ND2 1 
ATOM   1029 N N   . TYR A 1 184 ? 175.803 200.326 112.474 1.00 19.39  ? 191 TYR A N   1 
ATOM   1030 C CA  . TYR A 1 184 ? 175.978 200.720 113.872 1.00 16.46  ? 191 TYR A CA  1 
ATOM   1031 C C   . TYR A 1 184 ? 176.178 199.461 114.691 1.00 15.40  ? 191 TYR A C   1 
ATOM   1032 O O   . TYR A 1 184 ? 175.894 198.396 114.197 1.00 19.00  ? 191 TYR A O   1 
ATOM   1033 C CB  . TYR A 1 184 ? 174.662 201.309 114.339 1.00 16.05  ? 191 TYR A CB  1 
ATOM   1034 C CG  . TYR A 1 184 ? 174.367 202.702 113.853 1.00 20.06  ? 191 TYR A CG  1 
ATOM   1035 C CD1 . TYR A 1 184 ? 173.987 202.945 112.547 1.00 24.32  ? 191 TYR A CD1 1 
ATOM   1036 C CD2 . TYR A 1 184 ? 174.451 203.779 114.711 1.00 18.67  ? 191 TYR A CD2 1 
ATOM   1037 C CE1 . TYR A 1 184 ? 173.714 204.224 112.099 1.00 23.41  ? 191 TYR A CE1 1 
ATOM   1038 C CE2 . TYR A 1 184 ? 174.174 205.063 114.284 1.00 19.00  ? 191 TYR A CE2 1 
ATOM   1039 C CZ  . TYR A 1 184 ? 173.809 205.286 112.974 1.00 22.14  ? 191 TYR A CZ  1 
ATOM   1040 O OH  . TYR A 1 184 ? 173.541 206.553 112.553 1.00 26.09  ? 191 TYR A OH  1 
ATOM   1041 N N   . ARG A 1 185 ? 176.804 199.606 115.859 1.00 15.76  ? 192 ARG A N   1 
ATOM   1042 C CA  . ARG A 1 185 ? 176.969 198.494 116.811 1.00 14.67  ? 192 ARG A CA  1 
ATOM   1043 C C   . ARG A 1 185 ? 176.286 198.976 118.086 1.00 13.93  ? 192 ARG A C   1 
ATOM   1044 O O   . ARG A 1 185 ? 175.943 200.128 118.132 1.00 16.65  ? 192 ARG A O   1 
ATOM   1045 C CB  . ARG A 1 185 ? 178.440 198.149 117.035 1.00 16.24  ? 192 ARG A CB  1 
ATOM   1046 C CG  . ARG A 1 185 ? 179.310 199.272 117.556 1.00 16.36  ? 192 ARG A CG  1 
ATOM   1047 C CD  . ARG A 1 185 ? 180.479 198.643 118.274 1.00 17.22  ? 192 ARG A CD  1 
ATOM   1048 N NE  . ARG A 1 185 ? 181.431 199.628 118.751 1.00 20.80  ? 192 ARG A NE  1 
ATOM   1049 C CZ  . ARG A 1 185 ? 181.436 200.130 119.973 1.00 21.11  ? 192 ARG A CZ  1 
ATOM   1050 N NH1 . ARG A 1 185 ? 180.528 199.750 120.849 1.00 20.67  ? 192 ARG A NH1 1 
ATOM   1051 N NH2 . ARG A 1 185 ? 182.344 201.021 120.313 1.00 24.80  ? 192 ARG A NH2 1 
ATOM   1052 N N   . LEU A 1 186 ? 176.048 198.118 119.056 1.00 14.15  ? 193 LEU A N   1 
ATOM   1053 C CA  . LEU A 1 186 ? 175.508 198.539 120.356 1.00 13.24  ? 193 LEU A CA  1 
ATOM   1054 C C   . LEU A 1 186 ? 176.622 199.244 121.095 1.00 13.74  ? 193 LEU A C   1 
ATOM   1055 O O   . LEU A 1 186 ? 177.739 199.056 120.716 1.00 18.48  ? 193 LEU A O   1 
ATOM   1056 C CB  . LEU A 1 186 ? 174.963 197.317 121.097 1.00 14.75  ? 193 LEU A CB  1 
ATOM   1057 C CG  . LEU A 1 186 ? 173.589 196.805 120.667 1.00 12.52  ? 193 LEU A CG  1 
ATOM   1058 C CD1 . LEU A 1 186 ? 173.218 195.564 121.451 1.00 13.59  ? 193 LEU A CD1 1 
ATOM   1059 C CD2 . LEU A 1 186 ? 172.522 197.865 120.848 1.00 9.96   ? 193 LEU A CD2 1 
ATOM   1060 N N   . ILE A 1 187 ? 176.319 200.050 122.097 1.00 17.56  ? 194 ILE A N   1 
ATOM   1061 C CA  . ILE A 1 187 ? 177.324 200.902 122.807 1.00 18.68  ? 194 ILE A CA  1 
ATOM   1062 C C   . ILE A 1 187 ? 178.388 200.082 123.541 1.00 21.59  ? 194 ILE A C   1 
ATOM   1063 O O   . ILE A 1 187 ? 179.546 200.496 123.528 1.00 22.79  ? 194 ILE A O   1 
ATOM   1064 C CB  . ILE A 1 187 ? 176.612 201.936 123.709 1.00 17.13  ? 194 ILE A CB  1 
ATOM   1065 C CG1 . ILE A 1 187 ? 177.532 203.056 124.191 1.00 19.04  ? 194 ILE A CG1 1 
ATOM   1066 C CG2 . ILE A 1 187 ? 175.865 201.286 124.854 1.00 17.70  ? 194 ILE A CG2 1 
ATOM   1067 C CD1 . ILE A 1 187 ? 177.627 204.214 123.236 1.00 24.57  ? 194 ILE A CD1 1 
ATOM   1068 N N   . ASN A 1 188 ? 178.037 198.962 124.137 1.00 21.06  ? 195 ASN A N   1 
ATOM   1069 C CA  . ASN A 1 188 ? 178.940 198.203 125.018 1.00 21.02  ? 195 ASN A CA  1 
ATOM   1070 C C   . ASN A 1 188 ? 179.741 197.108 124.344 1.00 20.70  ? 195 ASN A C   1 
ATOM   1071 O O   . ASN A 1 188 ? 180.474 196.449 125.031 1.00 23.98  ? 195 ASN A O   1 
ATOM   1072 C CB  . ASN A 1 188 ? 178.027 197.427 125.947 1.00 30.00  ? 195 ASN A CB  1 
ATOM   1073 C CG  . ASN A 1 188 ? 177.164 196.402 125.241 1.00 30.00  ? 195 ASN A CG  1 
ATOM   1074 O OD1 . ASN A 1 188 ? 177.425 195.209 125.313 1.00 30.00  ? 195 ASN A OD1 1 
ATOM   1075 N ND2 . ASN A 1 188 ? 176.117 196.850 124.574 1.00 30.00  ? 195 ASN A ND2 1 
ATOM   1076 N N   . CYS A 1 189 ? 179.621 196.928 123.052 1.00 21.59  ? 196 CYS A N   1 
ATOM   1077 C CA  . CYS A 1 189 ? 180.244 195.780 122.374 1.00 19.96  ? 196 CYS A CA  1 
ATOM   1078 C C   . CYS A 1 189 ? 181.768 195.865 122.497 1.00 20.85  ? 196 CYS A C   1 
ATOM   1079 O O   . CYS A 1 189 ? 182.398 194.819 122.436 1.00 25.31  ? 196 CYS A O   1 
ATOM   1080 C CB  . CYS A 1 189 ? 179.626 195.619 120.990 1.00 18.25  ? 196 CYS A CB  1 
ATOM   1081 S SG  . CYS A 1 189 ? 178.087 194.665 120.968 1.00 20.07  ? 196 CYS A SG  1 
ATOM   1082 N N   . ASN A 1 190 ? 182.329 197.056 122.679 1.00 22.89  ? 197 ASN A N   1 
ATOM   1083 C CA  . ASN A 1 190 ? 183.795 197.229 122.852 1.00 22.78  ? 197 ASN A CA  1 
ATOM   1084 C C   . ASN A 1 190 ? 184.279 197.214 124.307 1.00 23.82  ? 197 ASN A C   1 
ATOM   1085 O O   . ASN A 1 190 ? 185.488 197.319 124.499 1.00 29.69  ? 197 ASN A O   1 
ATOM   1086 C CB  . ASN A 1 190 ? 184.354 198.464 122.159 1.00 25.33  ? 197 ASN A CB  1 
ATOM   1087 C CG  . ASN A 1 190 ? 184.075 199.799 122.807 1.00 26.55  ? 197 ASN A CG  1 
ATOM   1088 O OD1 . ASN A 1 190 ? 183.290 199.908 123.741 1.00 28.75  ? 197 ASN A OD1 1 
ATOM   1089 N ND2 . ASN A 1 190 ? 184.724 200.829 122.292 1.00 29.59  ? 197 ASN A ND2 1 
ATOM   1090 N N   . THR A 1 191 ? 183.396 197.151 125.295 1.00 23.86  ? 198 THR A N   1 
ATOM   1091 C CA  . THR A 1 191 ? 183.859 197.217 126.691 1.00 21.68  ? 198 THR A CA  1 
ATOM   1092 C C   . THR A 1 191 ? 183.259 196.105 127.526 1.00 22.49  ? 198 THR A C   1 
ATOM   1093 O O   . THR A 1 191 ? 183.864 195.751 128.530 1.00 16.99  ? 198 THR A O   1 
ATOM   1094 C CB  . THR A 1 191 ? 183.507 198.564 127.326 1.00 26.14  ? 198 THR A CB  1 
ATOM   1095 O OG1 . THR A 1 191 ? 183.455 198.400 128.742 1.00 29.93  ? 198 THR A OG1 1 
ATOM   1096 C CG2 . THR A 1 191 ? 182.187 199.136 126.860 1.00 27.12  ? 198 THR A CG2 1 
ATOM   1097 N N   . SER A 1 192 ? 182.107 195.589 127.137 1.00 23.57  ? 199 SER A N   1 
ATOM   1098 C CA  . SER A 1 192 ? 181.463 194.623 128.046 1.00 26.84  ? 199 SER A CA  1 
ATOM   1099 C C   . SER A 1 192 ? 180.446 193.721 127.393 1.00 24.58  ? 199 SER A C   1 
ATOM   1100 O O   . SER A 1 192 ? 180.098 193.943 126.261 1.00 26.12  ? 199 SER A O   1 
ATOM   1101 C CB  . SER A 1 192 ? 180.751 195.358 129.150 1.00 31.49  ? 199 SER A CB  1 
ATOM   1102 O OG  . SER A 1 192 ? 179.887 196.359 128.649 1.00 30.60  ? 199 SER A OG  1 
ATOM   1103 N N   . ALA A 1 193 ? 180.029 192.710 128.118 1.00 24.44  ? 200 ALA A N   1 
ATOM   1104 C CA  . ALA A 1 193 ? 178.896 191.901 127.673 1.00 23.90  ? 200 ALA A CA  1 
ATOM   1105 C C   . ALA A 1 193 ? 177.658 192.457 128.385 1.00 22.55  ? 200 ALA A C   1 
ATOM   1106 O O   . ALA A 1 193 ? 177.750 192.699 129.580 1.00 22.08  ? 200 ALA A O   1 
ATOM   1107 C CB  . ALA A 1 193 ? 179.147 190.508 128.131 1.00 28.39  ? 200 ALA A CB  1 
ATOM   1108 N N   . ILE A 1 194 ? 176.565 192.671 127.662 1.00 20.54  ? 201 ILE A N   1 
ATOM   1109 C CA  . ILE A 1 194 ? 175.353 193.246 128.285 1.00 17.34  ? 201 ILE A CA  1 
ATOM   1110 C C   . ILE A 1 194 ? 174.581 192.082 128.826 1.00 15.39  ? 201 ILE A C   1 
ATOM   1111 O O   . ILE A 1 194 ? 174.591 191.039 128.238 1.00 17.45  ? 201 ILE A O   1 
ATOM   1112 C CB  . ILE A 1 194 ? 174.471 194.146 127.398 1.00 16.11  ? 201 ILE A CB  1 
ATOM   1113 C CG1 . ILE A 1 194 ? 174.512 193.725 125.930 1.00 22.42  ? 201 ILE A CG1 1 
ATOM   1114 C CG2 . ILE A 1 194 ? 174.803 195.609 127.583 1.00 14.60  ? 201 ILE A CG2 1 
ATOM   1115 C CD1 . ILE A 1 194 ? 173.506 194.434 125.066 1.00 23.74  ? 201 ILE A CD1 1 
ATOM   1116 N N   . THR A 1 195 ? 174.048 192.268 129.995 1.00 14.83  ? 202 THR A N   1 
ATOM   1117 C CA  . THR A 1 195 ? 173.136 191.226 130.491 1.00 13.00  ? 202 THR A CA  1 
ATOM   1118 C C   . THR A 1 195 ? 171.714 191.754 130.495 1.00 12.68  ? 202 THR A C   1 
ATOM   1119 O O   . THR A 1 195 ? 171.494 192.869 130.937 1.00 15.20  ? 202 THR A O   1 
ATOM   1120 C CB  . THR A 1 195 ? 173.516 190.770 131.915 1.00 14.19  ? 202 THR A CB  1 
ATOM   1121 O OG1 . THR A 1 195 ? 174.833 190.226 131.891 1.00 20.12  ? 202 THR A OG1 1 
ATOM   1122 C CG2 . THR A 1 195 ? 172.540 189.698 132.433 1.00 16.01  ? 202 THR A CG2 1 
ATOM   1123 N N   . GLN A 1 196 ? 170.747 190.999 129.990 1.00 12.55  ? 203 GLN A N   1 
ATOM   1124 C CA  . GLN A 1 196 ? 169.365 191.463 129.998 1.00 12.05  ? 203 GLN A CA  1 
ATOM   1125 C C   . GLN A 1 196 ? 168.761 191.272 131.354 1.00 15.05  ? 203 GLN A C   1 
ATOM   1126 O O   . GLN A 1 196 ? 168.861 190.203 131.917 1.00 17.90  ? 203 GLN A O   1 
ATOM   1127 C CB  . GLN A 1 196 ? 168.534 190.704 128.958 1.00 12.62  ? 203 GLN A CB  1 
ATOM   1128 C CG  . GLN A 1 196 ? 167.055 191.100 128.850 1.00 12.04  ? 203 GLN A CG  1 
ATOM   1129 C CD  . GLN A 1 196 ? 166.365 190.425 127.695 1.00 11.07  ? 203 GLN A CD  1 
ATOM   1130 O OE1 . GLN A 1 196 ? 166.043 191.039 126.665 1.00 12.21  ? 203 GLN A OE1 1 
ATOM   1131 N NE2 . GLN A 1 196 ? 166.158 189.136 127.868 1.00 12.94  ? 203 GLN A NE2 1 
ATOM   1132 N N   . ALA A 1 197 ? 168.106 192.285 131.876 1.00 16.23  ? 204 ALA A N   1 
ATOM   1133 C CA  . ALA A 1 197 ? 167.423 192.128 133.145 1.00 17.64  ? 204 ALA A CA  1 
ATOM   1134 C C   . ALA A 1 197 ? 166.255 191.181 132.932 1.00 21.23  ? 204 ALA A C   1 
ATOM   1135 O O   . ALA A 1 197 ? 165.594 191.288 131.900 1.00 21.68  ? 204 ALA A O   1 
ATOM   1136 C CB  . ALA A 1 197 ? 166.934 193.465 133.657 1.00 18.34  ? 204 ALA A CB  1 
ATOM   1137 N N   . CYS A 1 198 ? 165.946 190.301 133.909 1.00 25.13  ? 205 CYS A N   1 
ATOM   1138 C CA  . CYS A 1 198 ? 164.822 189.369 133.852 1.00 26.26  ? 205 CYS A CA  1 
ATOM   1139 C C   . CYS A 1 198 ? 163.493 190.160 133.920 1.00 27.62  ? 205 CYS A C   1 
ATOM   1140 O O   . CYS A 1 198 ? 163.285 190.930 134.853 1.00 31.39  ? 205 CYS A O   1 
ATOM   1141 C CB  . CYS A 1 198 ? 164.910 188.346 135.021 1.00 31.71  ? 205 CYS A CB  1 
ATOM   1142 S SG  . CYS A 1 198 ? 166.301 187.114 134.963 1.00 33.55  ? 205 CYS A SG  1 
ATOM   1143 N N   . PRO A 1 199 ? 162.566 190.008 132.954 1.00 30.32  ? 206 PRO A N   1 
ATOM   1144 C CA  . PRO A 1 199 ? 161.269 190.684 132.892 1.00 30.55  ? 206 PRO A CA  1 
ATOM   1145 C C   . PRO A 1 199 ? 160.353 190.398 134.074 1.00 33.35  ? 206 PRO A C   1 
ATOM   1146 O O   . PRO A 1 199 ? 159.413 191.140 134.338 1.00 33.91  ? 206 PRO A O   1 
ATOM   1147 C CB  . PRO A 1 199 ? 160.657 190.115 131.612 1.00 28.88  ? 206 PRO A CB  1 
ATOM   1148 C CG  . PRO A 1 199 ? 161.817 189.687 130.782 1.00 24.00  ? 206 PRO A CG  1 
ATOM   1149 C CD  . PRO A 1 199 ? 162.866 189.212 131.753 1.00 27.90  ? 206 PRO A CD  1 
ATOM   1150 N N   . LYS A 1 200 ? 160.615 189.305 134.775 1.00 35.30  ? 207 LYS A N   1 
ATOM   1151 C CA  . LYS A 1 200 ? 159.808 188.907 135.914 1.00 36.88  ? 207 LYS A CA  1 
ATOM   1152 C C   . LYS A 1 200 ? 160.283 189.547 137.213 1.00 35.58  ? 207 LYS A C   1 
ATOM   1153 O O   . LYS A 1 200 ? 159.672 189.347 138.264 1.00 37.21  ? 207 LYS A O   1 
ATOM   1154 C CB  . LYS A 1 200 ? 159.792 187.384 136.055 1.00 39.97  ? 207 LYS A CB  1 
ATOM   1155 C CG  . LYS A 1 200 ? 161.109 186.775 136.504 1.00 41.43  ? 207 LYS A CG  1 
ATOM   1156 C CD  . LYS A 1 200 ? 161.051 185.262 136.555 1.00 50.57  ? 207 LYS A CD  1 
ATOM   1157 C CE  . LYS A 1 200 ? 162.391 184.678 137.009 1.00 56.70  ? 207 LYS A CE  1 
ATOM   1158 N NZ  . LYS A 1 200 ? 162.368 183.186 137.037 1.00 62.93  ? 207 LYS A NZ  1 
ATOM   1159 N N   . VAL A 1 201 ? 161.406 190.254 137.171 1.00 34.98  ? 208 VAL A N   1 
ATOM   1160 C CA  . VAL A 1 201 ? 161.959 190.848 138.369 1.00 33.75  ? 208 VAL A CA  1 
ATOM   1161 C C   . VAL A 1 201 ? 161.811 192.354 138.290 1.00 34.37  ? 208 VAL A C   1 
ATOM   1162 O O   . VAL A 1 201 ? 162.314 192.985 137.364 1.00 33.27  ? 208 VAL A O   1 
ATOM   1163 C CB  . VAL A 1 201 ? 163.439 190.466 138.513 1.00 33.44  ? 208 VAL A CB  1 
ATOM   1164 C CG1 . VAL A 1 201 ? 164.033 191.099 139.757 1.00 32.80  ? 208 VAL A CG1 1 
ATOM   1165 C CG2 . VAL A 1 201 ? 163.561 188.960 138.555 1.00 36.28  ? 208 VAL A CG2 1 
ATOM   1166 N N   . SER A 1 202 ? 161.110 192.923 139.255 1.00 33.57  ? 209 SER A N   1 
ATOM   1167 C CA  . SER A 1 202 ? 160.865 194.350 139.281 1.00 32.96  ? 209 SER A CA  1 
ATOM   1168 C C   . SER A 1 202 ? 162.059 195.114 139.821 1.00 30.92  ? 209 SER A C   1 
ATOM   1169 O O   . SER A 1 202 ? 162.940 194.550 140.468 1.00 31.12  ? 209 SER A O   1 
ATOM   1170 C CB  . SER A 1 202 ? 159.649 194.636 140.123 1.00 33.71  ? 209 SER A CB  1 
ATOM   1171 O OG  . SER A 1 202 ? 159.896 194.333 141.460 1.00 33.30  ? 209 SER A OG  1 
ATOM   1172 N N   . PHE A 1 203 ? 162.056 196.425 139.595 1.00 29.49  ? 210 PHE A N   1 
ATOM   1173 C CA  . PHE A 1 203 ? 163.094 197.304 140.118 1.00 28.12  ? 210 PHE A CA  1 
ATOM   1174 C C   . PHE A 1 203 ? 162.557 198.164 141.255 1.00 29.15  ? 210 PHE A C   1 
ATOM   1175 O O   . PHE A 1 203 ? 163.147 199.183 141.603 1.00 28.94  ? 210 PHE A O   1 
ATOM   1176 C CB  . PHE A 1 203 ? 163.651 198.244 139.042 1.00 26.20  ? 210 PHE A CB  1 
ATOM   1177 C CG  . PHE A 1 203 ? 164.372 197.612 137.852 1.00 25.27  ? 210 PHE A CG  1 
ATOM   1178 C CD1 . PHE A 1 203 ? 165.576 196.972 138.002 1.00 24.88  ? 210 PHE A CD1 1 
ATOM   1179 C CD2 . PHE A 1 203 ? 163.840 197.684 136.589 1.00 22.21  ? 210 PHE A CD2 1 
ATOM   1180 C CE1 . PHE A 1 203 ? 166.233 196.431 136.921 1.00 22.86  ? 210 PHE A CE1 1 
ATOM   1181 C CE2 . PHE A 1 203 ? 164.493 197.155 135.507 1.00 22.38  ? 210 PHE A CE2 1 
ATOM   1182 C CZ  . PHE A 1 203 ? 165.689 196.530 135.676 1.00 22.70  ? 210 PHE A CZ  1 
ATOM   1183 N N   . GLU A 1 204 ? 161.404 197.787 141.787 1.00 30.76  ? 211 GLU A N   1 
ATOM   1184 C CA  . GLU A 1 204 ? 160.752 198.542 142.839 1.00 31.03  ? 211 GLU A CA  1 
ATOM   1185 C C   . GLU A 1 204 ? 161.639 198.619 144.098 1.00 31.06  ? 211 GLU A C   1 
ATOM   1186 O O   . GLU A 1 204 ? 162.106 197.592 144.594 1.00 30.27  ? 211 GLU A O   1 
ATOM   1187 C CB  . GLU A 1 204 ? 159.409 197.901 143.178 1.00 35.31  ? 211 GLU A CB  1 
ATOM   1188 C CG  . GLU A 1 204 ? 158.570 198.693 144.156 1.00 38.46  ? 211 GLU A CG  1 
ATOM   1189 C CD  . GLU A 1 204 ? 157.246 198.085 144.456 1.00 48.25  ? 211 GLU A CD  1 
ATOM   1190 O OE1 . GLU A 1 204 ? 156.948 197.034 143.947 1.00 48.83  ? 211 GLU A OE1 1 
ATOM   1191 O OE2 . GLU A 1 204 ? 156.518 198.680 145.208 1.00 56.49  ? 211 GLU A OE2 1 
ATOM   1192 N N   . PRO A 1 205 ? 161.852 199.806 144.683 1.00 27.28  ? 212 PRO A N   1 
ATOM   1193 C CA  . PRO A 1 205 ? 162.661 200.049 145.853 1.00 22.62  ? 212 PRO A CA  1 
ATOM   1194 C C   . PRO A 1 205 ? 161.967 199.658 147.144 1.00 23.68  ? 212 PRO A C   1 
ATOM   1195 O O   . PRO A 1 205 ? 161.531 200.516 147.899 1.00 25.16  ? 212 PRO A O   1 
ATOM   1196 C CB  . PRO A 1 205 ? 162.919 201.543 145.760 1.00 19.74  ? 212 PRO A CB  1 
ATOM   1197 C CG  . PRO A 1 205 ? 161.705 202.081 145.100 1.00 21.60  ? 212 PRO A CG  1 
ATOM   1198 C CD  . PRO A 1 205 ? 161.304 201.034 144.106 1.00 26.74  ? 212 PRO A CD  1 
ATOM   1199 N N   . ILE A 1 206 ? 161.855 198.364 147.372 1.00 25.75  ? 213 ILE A N   1 
ATOM   1200 C CA  . ILE A 1 206 ? 161.198 197.803 148.553 1.00 23.95  ? 213 ILE A CA  1 
ATOM   1201 C C   . ILE A 1 206 ? 162.009 198.162 149.806 1.00 21.85  ? 213 ILE A C   1 
ATOM   1202 O O   . ILE A 1 206 ? 163.213 197.931 149.802 1.00 22.58  ? 213 ILE A O   1 
ATOM   1203 C CB  . ILE A 1 206 ? 161.121 196.266 148.440 1.00 25.89  ? 213 ILE A CB  1 
ATOM   1204 C CG1 . ILE A 1 206 ? 160.303 195.843 147.183 1.00 30.52  ? 213 ILE A CG1 1 
ATOM   1205 C CG2 . ILE A 1 206 ? 160.570 195.631 149.712 1.00 25.58  ? 213 ILE A CG2 1 
ATOM   1206 C CD1 . ILE A 1 206 ? 158.857 196.314 147.122 1.00 35.42  ? 213 ILE A CD1 1 
ATOM   1207 N N   . PRO A 1 207 ? 161.399 198.695 150.893 1.00 20.81  ? 214 PRO A N   1 
ATOM   1208 C CA  . PRO A 1 207 ? 162.060 199.100 152.125 1.00 19.19  ? 214 PRO A CA  1 
ATOM   1209 C C   . PRO A 1 207 ? 162.865 198.018 152.817 1.00 20.15  ? 214 PRO A C   1 
ATOM   1210 O O   . PRO A 1 207 ? 162.410 196.884 152.950 1.00 22.85  ? 214 PRO A O   1 
ATOM   1211 C CB  . PRO A 1 207 ? 160.876 199.430 153.036 1.00 18.33  ? 214 PRO A CB  1 
ATOM   1212 C CG  . PRO A 1 207 ? 159.774 199.811 152.134 1.00 19.68  ? 214 PRO A CG  1 
ATOM   1213 C CD  . PRO A 1 207 ? 159.944 198.958 150.904 1.00 22.00  ? 214 PRO A CD  1 
ATOM   1214 N N   . ILE A 1 208 ? 164.025 198.413 153.321 1.00 20.88  ? 215 ILE A N   1 
ATOM   1215 C CA  . ILE A 1 208 ? 164.923 197.563 154.087 1.00 20.85  ? 215 ILE A CA  1 
ATOM   1216 C C   . ILE A 1 208 ? 165.192 198.158 155.456 1.00 20.53  ? 215 ILE A C   1 
ATOM   1217 O O   . ILE A 1 208 ? 165.477 199.348 155.571 1.00 21.29  ? 215 ILE A O   1 
ATOM   1218 C CB  . ILE A 1 208 ? 166.273 197.335 153.344 1.00 23.62  ? 215 ILE A CB  1 
ATOM   1219 C CG1 . ILE A 1 208 ? 167.177 196.393 154.190 1.00 26.33  ? 215 ILE A CG1 1 
ATOM   1220 C CG2 . ILE A 1 208 ? 167.008 198.673 153.017 1.00 22.37  ? 215 ILE A CG2 1 
ATOM   1221 C CD1 . ILE A 1 208 ? 168.380 195.832 153.465 1.00 31.05  ? 215 ILE A CD1 1 
ATOM   1222 N N   . HIS A 1 209 ? 165.124 197.347 156.500 1.00 24.22  ? 216 HIS A N   1 
ATOM   1223 C CA  . HIS A 1 209 ? 165.434 197.827 157.830 1.00 18.58  ? 216 HIS A CA  1 
ATOM   1224 C C   . HIS A 1 209 ? 166.791 197.247 158.207 1.00 20.32  ? 216 HIS A C   1 
ATOM   1225 O O   . HIS A 1 209 ? 167.060 196.085 157.894 1.00 26.95  ? 216 HIS A O   1 
ATOM   1226 C CB  . HIS A 1 209 ? 164.407 197.302 158.822 1.00 18.96  ? 216 HIS A CB  1 
ATOM   1227 C CG  . HIS A 1 209 ? 162.993 197.653 158.571 1.00 19.51  ? 216 HIS A CG  1 
ATOM   1228 N ND1 . HIS A 1 209 ? 162.340 198.591 159.300 1.00 20.31  ? 216 HIS A ND1 1 
ATOM   1229 C CD2 . HIS A 1 209 ? 162.104 197.195 157.665 1.00 21.60  ? 216 HIS A CD2 1 
ATOM   1230 C CE1 . HIS A 1 209 ? 161.101 198.696 158.875 1.00 20.29  ? 216 HIS A CE1 1 
ATOM   1231 N NE2 . HIS A 1 209 ? 160.930 197.862 157.880 1.00 20.15  ? 216 HIS A NE2 1 
ATOM   1232 N N   . TYR A 1 210 ? 167.660 198.025 158.852 1.00 18.19  ? 217 TYR A N   1 
ATOM   1233 C CA  . TYR A 1 210 ? 168.934 197.475 159.335 1.00 18.11  ? 217 TYR A CA  1 
ATOM   1234 C C   . TYR A 1 210 ? 168.918 197.288 160.845 1.00 18.47  ? 217 TYR A C   1 
ATOM   1235 O O   . TYR A 1 210 ? 168.639 198.242 161.575 1.00 20.01  ? 217 TYR A O   1 
ATOM   1236 C CB  . TYR A 1 210 ? 170.118 198.323 158.919 1.00 18.30  ? 217 TYR A CB  1 
ATOM   1237 C CG  . TYR A 1 210 ? 170.496 198.153 157.501 1.00 20.44  ? 217 TYR A CG  1 
ATOM   1238 C CD1 . TYR A 1 210 ? 171.363 197.130 157.217 1.00 23.08  ? 217 TYR A CD1 1 
ATOM   1239 C CD2 . TYR A 1 210 ? 170.014 198.958 156.490 1.00 22.53  ? 217 TYR A CD2 1 
ATOM   1240 C CE1 . TYR A 1 210 ? 171.765 196.896 155.958 1.00 23.75  ? 217 TYR A CE1 1 
ATOM   1241 C CE2 . TYR A 1 210 ? 170.430 198.716 155.192 1.00 22.70  ? 217 TYR A CE2 1 
ATOM   1242 C CZ  . TYR A 1 210 ? 171.319 197.667 154.946 1.00 23.04  ? 217 TYR A CZ  1 
ATOM   1243 O OH  . TYR A 1 210 ? 171.762 197.391 153.681 1.00 22.71  ? 217 TYR A OH  1 
ATOM   1244 N N   . CYS A 1 211 ? 169.197 196.049 161.313 1.00 20.89  ? 218 CYS A N   1 
ATOM   1245 C CA  . CYS A 1 211 ? 169.116 195.639 162.716 1.00 18.71  ? 218 CYS A CA  1 
ATOM   1246 C C   . CYS A 1 211 ? 170.499 195.344 163.296 1.00 17.63  ? 218 CYS A C   1 
ATOM   1247 O O   . CYS A 1 211 ? 171.375 194.784 162.632 1.00 20.58  ? 218 CYS A O   1 
ATOM   1248 C CB  . CYS A 1 211 ? 168.238 194.382 162.849 1.00 20.33  ? 218 CYS A CB  1 
ATOM   1249 S SG  . CYS A 1 211 ? 166.495 194.510 162.270 1.00 21.43  ? 218 CYS A SG  1 
ATOM   1250 N N   . ALA A 1 212 ? 170.688 195.691 164.569 1.00 20.70  ? 219 ALA A N   1 
ATOM   1251 C CA  . ALA A 1 212 ? 171.982 195.430 165.209 1.00 19.42  ? 219 ALA A CA  1 
ATOM   1252 C C   . ALA A 1 212 ? 172.085 194.014 165.777 1.00 20.73  ? 219 ALA A C   1 
ATOM   1253 O O   . ALA A 1 212 ? 171.079 193.441 166.188 1.00 21.29  ? 219 ALA A O   1 
ATOM   1254 C CB  . ALA A 1 212 ? 172.239 196.426 166.324 1.00 16.66  ? 219 ALA A CB  1 
ATOM   1255 N N   . PRO A 1 213 ? 173.282 193.407 165.781 1.00 18.58  ? 220 PRO A N   1 
ATOM   1256 C CA  . PRO A 1 213 ? 173.597 192.150 166.417 1.00 18.33  ? 220 PRO A CA  1 
ATOM   1257 C C   . PRO A 1 213 ? 173.639 192.328 167.923 1.00 17.13  ? 220 PRO A C   1 
ATOM   1258 O O   . PRO A 1 213 ? 173.889 193.432 168.401 1.00 16.87  ? 220 PRO A O   1 
ATOM   1259 C CB  . PRO A 1 213 ? 174.958 191.809 165.823 1.00 19.29  ? 220 PRO A CB  1 
ATOM   1260 C CG  . PRO A 1 213 ? 175.560 193.127 165.472 1.00 17.56  ? 220 PRO A CG  1 
ATOM   1261 C CD  . PRO A 1 213 ? 174.420 193.993 165.055 1.00 17.91  ? 220 PRO A CD  1 
ATOM   1262 N N   . ALA A 1 214 ? 173.456 191.254 168.672 1.00 18.03  ? 221 ALA A N   1 
ATOM   1263 C CA  . ALA A 1 214 ? 173.519 191.367 170.120 1.00 15.48  ? 221 ALA A CA  1 
ATOM   1264 C C   . ALA A 1 214 ? 174.871 191.879 170.548 1.00 13.51  ? 221 ALA A C   1 
ATOM   1265 O O   . ALA A 1 214 ? 175.901 191.497 169.996 1.00 14.74  ? 221 ALA A O   1 
ATOM   1266 C CB  . ALA A 1 214 ? 173.232 190.042 170.772 1.00 17.68  ? 221 ALA A CB  1 
ATOM   1267 N N   . GLY A 1 215 ? 174.863 192.738 171.557 1.00 12.77  ? 222 GLY A N   1 
ATOM   1268 C CA  . GLY A 1 215 ? 176.078 193.342 172.071 1.00 10.95  ? 222 GLY A CA  1 
ATOM   1269 C C   . GLY A 1 215 ? 176.255 194.749 171.516 1.00 10.01  ? 222 GLY A C   1 
ATOM   1270 O O   . GLY A 1 215 ? 177.131 195.482 171.966 1.00 9.58   ? 222 GLY A O   1 
ATOM   1271 N N   . PHE A 1 216 ? 175.429 195.097 170.529 1.00 11.65  ? 223 PHE A N   1 
ATOM   1272 C CA  . PHE A 1 216 ? 175.396 196.387 169.853 1.00 8.97   ? 223 PHE A CA  1 
ATOM   1273 C C   . PHE A 1 216 ? 174.023 197.013 169.919 1.00 9.27   ? 223 PHE A C   1 
ATOM   1274 O O   . PHE A 1 216 ? 173.019 196.347 170.176 1.00 10.95  ? 223 PHE A O   1 
ATOM   1275 C CB  . PHE A 1 216 ? 175.822 196.266 168.400 1.00 10.15  ? 223 PHE A CB  1 
ATOM   1276 C CG  . PHE A 1 216 ? 177.232 195.921 168.211 1.00 9.92   ? 223 PHE A CG  1 
ATOM   1277 C CD1 . PHE A 1 216 ? 177.658 194.635 168.277 1.00 11.22  ? 223 PHE A CD1 1 
ATOM   1278 C CD2 . PHE A 1 216 ? 178.146 196.904 167.930 1.00 9.45   ? 223 PHE A CD2 1 
ATOM   1279 C CE1 . PHE A 1 216 ? 178.966 194.335 168.083 1.00 10.06  ? 223 PHE A CE1 1 
ATOM   1280 C CE2 . PHE A 1 216 ? 179.445 196.603 167.734 1.00 10.39  ? 223 PHE A CE2 1 
ATOM   1281 C CZ  . PHE A 1 216 ? 179.861 195.322 167.813 1.00 10.31  ? 223 PHE A CZ  1 
ATOM   1282 N N   . ALA A 1 217 ? 173.978 198.316 169.723 1.00 8.68   ? 224 ALA A N   1 
ATOM   1283 C CA  . ALA A 1 217 ? 172.714 199.025 169.705 1.00 7.61   ? 224 ALA A CA  1 
ATOM   1284 C C   . ALA A 1 217 ? 172.735 200.154 168.706 1.00 8.23   ? 224 ALA A C   1 
ATOM   1285 O O   . ALA A 1 217 ? 173.783 200.722 168.407 1.00 8.74   ? 224 ALA A O   1 
ATOM   1286 C CB  . ALA A 1 217 ? 172.409 199.576 171.079 1.00 7.72   ? 224 ALA A CB  1 
ATOM   1287 N N   . ILE A 1 218 ? 171.567 200.505 168.195 1.00 10.66  ? 225 ILE A N   1 
ATOM   1288 C CA  . ILE A 1 218 ? 171.467 201.634 167.291 1.00 8.60   ? 225 ILE A CA  1 
ATOM   1289 C C   . ILE A 1 218 ? 170.825 202.782 168.023 1.00 8.88   ? 225 ILE A C   1 
ATOM   1290 O O   . ILE A 1 218 ? 169.761 202.629 168.613 1.00 10.89  ? 225 ILE A O   1 
ATOM   1291 C CB  . ILE A 1 218 ? 170.628 201.294 166.033 1.00 9.78   ? 225 ILE A CB  1 
ATOM   1292 C CG1 . ILE A 1 218 ? 171.266 200.164 165.272 1.00 10.94  ? 225 ILE A CG1 1 
ATOM   1293 C CG2 . ILE A 1 218 ? 170.517 202.524 165.138 1.00 9.54   ? 225 ILE A CG2 1 
ATOM   1294 C CD1 . ILE A 1 218 ? 170.406 199.528 164.190 1.00 14.50  ? 225 ILE A CD1 1 
ATOM   1295 N N   . LEU A 1 219 ? 171.487 203.913 168.037 1.00 8.14   ? 226 LEU A N   1 
ATOM   1296 C CA  . LEU A 1 219 ? 170.937 205.076 168.687 1.00 8.10   ? 226 LEU A CA  1 
ATOM   1297 C C   . LEU A 1 219 ? 170.319 205.919 167.605 1.00 6.59   ? 226 LEU A C   1 
ATOM   1298 O O   . LEU A 1 219 ? 170.825 205.972 166.489 1.00 8.48   ? 226 LEU A O   1 
ATOM   1299 C CB  . LEU A 1 219 ? 172.013 205.858 169.437 1.00 7.92   ? 226 LEU A CB  1 
ATOM   1300 C CG  . LEU A 1 219 ? 172.806 205.101 170.515 1.00 6.95   ? 226 LEU A CG  1 
ATOM   1301 C CD1 . LEU A 1 219 ? 173.817 206.025 171.075 1.00 6.29   ? 226 LEU A CD1 1 
ATOM   1302 C CD2 . LEU A 1 219 ? 171.898 204.577 171.615 1.00 7.56   ? 226 LEU A CD2 1 
ATOM   1303 N N   . LYS A 1 220 ? 169.246 206.604 167.927 1.00 8.19   ? 227 LYS A N   1 
ATOM   1304 C CA  . LYS A 1 220 ? 168.564 207.464 166.982 1.00 8.36   ? 227 LYS A CA  1 
ATOM   1305 C C   . LYS A 1 220 ? 168.404 208.879 167.539 1.00 8.87   ? 227 LYS A C   1 
ATOM   1306 O O   . LYS A 1 220 ? 167.989 209.047 168.690 1.00 12.07  ? 227 LYS A O   1 
ATOM   1307 C CB  . LYS A 1 220 ? 167.184 206.868 166.677 1.00 9.07   ? 227 LYS A CB  1 
ATOM   1308 C CG  . LYS A 1 220 ? 166.325 207.674 165.712 1.00 10.30  ? 227 LYS A CG  1 
ATOM   1309 C CD  . LYS A 1 220 ? 165.006 206.978 165.382 1.00 11.54  ? 227 LYS A CD  1 
ATOM   1310 C CE  . LYS A 1 220 ? 164.079 206.968 166.578 1.00 16.69  ? 227 LYS A CE  1 
ATOM   1311 N NZ  . LYS A 1 220 ? 162.707 206.498 166.254 1.00 21.36  ? 227 LYS A NZ  1 
ATOM   1312 N N   . CYS A 1 221 ? 168.685 209.904 166.709 1.00 10.01  ? 228 CYS A N   1 
ATOM   1313 C CA  . CYS A 1 221 ? 168.542 211.312 167.053 1.00 9.96   ? 228 CYS A CA  1 
ATOM   1314 C C   . CYS A 1 221 ? 167.139 211.797 166.693 1.00 12.27  ? 228 CYS A C   1 
ATOM   1315 O O   . CYS A 1 221 ? 166.719 211.743 165.532 1.00 13.31  ? 228 CYS A O   1 
ATOM   1316 C CB  . CYS A 1 221 ? 169.612 212.163 166.338 1.00 10.38  ? 228 CYS A CB  1 
ATOM   1317 S SG  . CYS A 1 221 ? 169.563 213.933 166.718 1.00 22.35  ? 228 CYS A SG  1 
ATOM   1318 N N   . LYS A 1 222 ? 166.415 212.282 167.694 1.00 14.22  ? 229 LYS A N   1 
ATOM   1319 C CA  . LYS A 1 222 ? 165.049 212.748 167.528 1.00 14.14  ? 229 LYS A CA  1 
ATOM   1320 C C   . LYS A 1 222 ? 164.916 214.259 167.483 1.00 16.39  ? 229 LYS A C   1 
ATOM   1321 O O   . LYS A 1 222 ? 163.813 214.802 167.520 1.00 19.11  ? 229 LYS A O   1 
ATOM   1322 C CB  . LYS A 1 222 ? 164.156 212.195 168.613 1.00 14.94  ? 229 LYS A CB  1 
ATOM   1323 C CG  . LYS A 1 222 ? 164.000 210.709 168.557 1.00 14.61  ? 229 LYS A CG  1 
ATOM   1324 C CD  . LYS A 1 222 ? 162.844 210.249 169.409 1.00 17.07  ? 229 LYS A CD  1 
ATOM   1325 C CE  . LYS A 1 222 ? 163.126 210.392 170.875 1.00 17.12  ? 229 LYS A CE  1 
ATOM   1326 N NZ  . LYS A 1 222 ? 162.055 209.776 171.696 1.00 20.40  ? 229 LYS A NZ  1 
ATOM   1327 N N   . ASP A 1 223 ? 166.030 214.948 167.417 1.00 16.59  ? 230 ASP A N   1 
ATOM   1328 C CA  . ASP A 1 223 ? 166.026 216.393 167.353 1.00 18.15  ? 230 ASP A CA  1 
ATOM   1329 C C   . ASP A 1 223 ? 165.633 216.858 165.954 1.00 21.84  ? 230 ASP A C   1 
ATOM   1330 O O   . ASP A 1 223 ? 166.330 216.597 164.972 1.00 22.15  ? 230 ASP A O   1 
ATOM   1331 C CB  . ASP A 1 223 ? 167.372 216.968 167.755 1.00 18.98  ? 230 ASP A CB  1 
ATOM   1332 C CG  . ASP A 1 223 ? 167.368 218.468 167.722 1.00 22.92  ? 230 ASP A CG  1 
ATOM   1333 O OD1 . ASP A 1 223 ? 166.325 219.015 167.378 1.00 24.36  ? 230 ASP A OD1 1 
ATOM   1334 O OD2 . ASP A 1 223 ? 168.366 219.069 168.032 1.00 22.61  ? 230 ASP A OD2 1 
ATOM   1335 N N   . LYS A 1 224 ? 164.482 217.516 165.863 1.00 23.38  ? 231 LYS A N   1 
ATOM   1336 C CA  . LYS A 1 224 ? 163.866 217.961 164.610 1.00 24.71  ? 231 LYS A CA  1 
ATOM   1337 C C   . LYS A 1 224 ? 164.702 218.978 163.846 1.00 24.24  ? 231 LYS A C   1 
ATOM   1338 O O   . LYS A 1 224 ? 164.501 219.190 162.652 1.00 25.27  ? 231 LYS A O   1 
ATOM   1339 C CB  . LYS A 1 224 ? 162.494 218.543 164.891 1.00 29.34  ? 231 LYS A CB  1 
ATOM   1340 C CG  . LYS A 1 224 ? 161.489 217.514 165.334 1.00 32.02  ? 231 LYS A CG  1 
ATOM   1341 C CD  . LYS A 1 224 ? 160.143 218.145 165.616 1.00 37.02  ? 231 LYS A CD  1 
ATOM   1342 C CE  . LYS A 1 224 ? 159.124 217.113 166.065 1.00 42.24  ? 231 LYS A CE  1 
ATOM   1343 N NZ  . LYS A 1 224 ? 157.813 217.740 166.389 1.00 48.20  ? 231 LYS A NZ  1 
ATOM   1344 N N   . LYS A 1 225 ? 165.603 219.655 164.531 1.00 23.63  ? 232 LYS A N   1 
ATOM   1345 C CA  . LYS A 1 225 ? 166.442 220.639 163.871 1.00 23.43  ? 232 LYS A CA  1 
ATOM   1346 C C   . LYS A 1 225 ? 167.857 220.140 163.651 1.00 22.08  ? 232 LYS A C   1 
ATOM   1347 O O   . LYS A 1 225 ? 168.741 220.912 163.276 1.00 22.20  ? 232 LYS A O   1 
ATOM   1348 C CB  . LYS A 1 225 ? 166.436 221.951 164.635 1.00 29.37  ? 232 LYS A CB  1 
ATOM   1349 C CG  . LYS A 1 225 ? 165.085 222.636 164.631 1.00 33.53  ? 232 LYS A CG  1 
ATOM   1350 C CD  . LYS A 1 225 ? 165.122 223.959 165.375 1.00 44.90  ? 232 LYS A CD  1 
ATOM   1351 C CE  . LYS A 1 225 ? 163.759 224.657 165.346 1.00 49.92  ? 232 LYS A CE  1 
ATOM   1352 N NZ  . LYS A 1 225 ? 163.412 225.151 163.978 1.00 46.91  ? 232 LYS A NZ  1 
ATOM   1353 N N   . PHE A 1 226 ? 168.093 218.861 163.902 1.00 22.56  ? 233 PHE A N   1 
ATOM   1354 C CA  . PHE A 1 226 ? 169.420 218.307 163.765 1.00 18.08  ? 233 PHE A CA  1 
ATOM   1355 C C   . PHE A 1 226 ? 169.870 218.309 162.310 1.00 16.40  ? 233 PHE A C   1 
ATOM   1356 O O   . PHE A 1 226 ? 169.140 217.819 161.437 1.00 18.84  ? 233 PHE A O   1 
ATOM   1357 C CB  . PHE A 1 226 ? 169.410 216.908 164.344 1.00 17.59  ? 233 PHE A CB  1 
ATOM   1358 C CG  . PHE A 1 226 ? 170.644 216.192 164.301 1.00 16.40  ? 233 PHE A CG  1 
ATOM   1359 C CD1 . PHE A 1 226 ? 171.716 216.561 165.085 1.00 15.63  ? 233 PHE A CD1 1 
ATOM   1360 C CD2 . PHE A 1 226 ? 170.743 215.096 163.503 1.00 16.62  ? 233 PHE A CD2 1 
ATOM   1361 C CE1 . PHE A 1 226 ? 172.854 215.860 165.031 1.00 14.12  ? 233 PHE A CE1 1 
ATOM   1362 C CE2 . PHE A 1 226 ? 171.877 214.396 163.461 1.00 15.61  ? 233 PHE A CE2 1 
ATOM   1363 C CZ  . PHE A 1 226 ? 172.925 214.786 164.211 1.00 14.51  ? 233 PHE A CZ  1 
ATOM   1364 N N   . ASN A 1 227 ? 171.100 218.829 162.073 1.00 16.49  ? 234 ASN A N   1 
ATOM   1365 C CA  . ASN A 1 227 ? 171.741 219.013 160.768 1.00 14.74  ? 234 ASN A CA  1 
ATOM   1366 C C   . ASN A 1 227 ? 172.800 217.942 160.417 1.00 15.40  ? 234 ASN A C   1 
ATOM   1367 O O   . ASN A 1 227 ? 173.624 218.168 159.525 1.00 17.42  ? 234 ASN A O   1 
ATOM   1368 C CB  . ASN A 1 227 ? 172.338 220.432 160.683 1.00 17.46  ? 234 ASN A CB  1 
ATOM   1369 C CG  . ASN A 1 227 ? 173.628 220.652 161.550 1.00 19.55  ? 234 ASN A CG  1 
ATOM   1370 O OD1 . ASN A 1 227 ? 173.863 219.926 162.536 1.00 20.04  ? 234 ASN A OD1 1 
ATOM   1371 N ND2 . ASN A 1 227 ? 174.430 221.638 161.167 1.00 23.27  ? 234 ASN A ND2 1 
ATOM   1372 N N   . GLY A 1 228 ? 172.821 216.796 161.117 1.00 14.80  ? 235 GLY A N   1 
ATOM   1373 C CA  . GLY A 1 228 ? 173.715 215.659 160.878 1.00 13.97  ? 235 GLY A CA  1 
ATOM   1374 C C   . GLY A 1 228 ? 174.949 215.575 161.758 1.00 14.29  ? 235 GLY A C   1 
ATOM   1375 O O   . GLY A 1 228 ? 175.532 214.498 161.889 1.00 15.60  ? 235 GLY A O   1 
ATOM   1376 N N   . THR A 1 229 ? 175.357 216.660 162.401 1.00 15.90  ? 236 THR A N   1 
ATOM   1377 C CA  . THR A 1 229 ? 176.535 216.580 163.251 1.00 14.39  ? 236 THR A CA  1 
ATOM   1378 C C   . THR A 1 229 ? 176.365 217.262 164.588 1.00 15.80  ? 236 THR A C   1 
ATOM   1379 O O   . THR A 1 229 ? 175.587 218.201 164.739 1.00 17.37  ? 236 THR A O   1 
ATOM   1380 C CB  . THR A 1 229 ? 177.772 217.196 162.582 1.00 14.70  ? 236 THR A CB  1 
ATOM   1381 O OG1 . THR A 1 229 ? 177.553 218.589 162.376 1.00 19.62  ? 236 THR A OG1 1 
ATOM   1382 C CG2 . THR A 1 229 ? 178.031 216.550 161.259 1.00 14.46  ? 236 THR A CG2 1 
ATOM   1383 N N   . GLY A 1 230 ? 177.199 216.874 165.533 1.00 16.41  ? 237 GLY A N   1 
ATOM   1384 C CA  . GLY A 1 230 ? 177.239 217.540 166.815 1.00 16.47  ? 237 GLY A CA  1 
ATOM   1385 C C   . GLY A 1 230 ? 176.331 216.851 167.802 1.00 15.86  ? 237 GLY A C   1 
ATOM   1386 O O   . GLY A 1 230 ? 175.810 215.769 167.517 1.00 16.48  ? 237 GLY A O   1 
ATOM   1387 N N   . PRO A 1 231 ? 176.191 217.391 169.006 1.00 17.07  ? 238 PRO A N   1 
ATOM   1388 C CA  . PRO A 1 231 ? 175.420 216.813 170.061 1.00 16.92  ? 238 PRO A CA  1 
ATOM   1389 C C   . PRO A 1 231 ? 173.954 216.835 169.687 1.00 16.66  ? 238 PRO A C   1 
ATOM   1390 O O   . PRO A 1 231 ? 173.504 217.800 169.066 1.00 18.07  ? 238 PRO A O   1 
ATOM   1391 C CB  . PRO A 1 231 ? 175.727 217.725 171.243 1.00 17.64  ? 238 PRO A CB  1 
ATOM   1392 C CG  . PRO A 1 231 ? 176.133 219.031 170.621 1.00 19.41  ? 238 PRO A CG  1 
ATOM   1393 C CD  . PRO A 1 231 ? 176.833 218.655 169.340 1.00 18.30  ? 238 PRO A CD  1 
ATOM   1394 N N   . CYS A 1 232 ? 173.227 215.800 170.110 1.00 15.34  ? 239 CYS A N   1 
ATOM   1395 C CA  . CYS A 1 232 ? 171.807 215.602 169.950 1.00 14.84  ? 239 CYS A CA  1 
ATOM   1396 C C   . CYS A 1 232 ? 171.243 215.374 171.363 1.00 15.75  ? 239 CYS A C   1 
ATOM   1397 O O   . CYS A 1 232 ? 171.559 214.365 172.004 1.00 17.11  ? 239 CYS A O   1 
ATOM   1398 C CB  . CYS A 1 232 ? 171.512 214.402 169.016 1.00 13.50  ? 239 CYS A CB  1 
ATOM   1399 S SG  . CYS A 1 232 ? 169.769 214.096 168.730 1.00 16.75  ? 239 CYS A SG  1 
ATOM   1400 N N   . PRO A 1 233 ? 170.469 216.323 171.912 1.00 16.60  ? 240 PRO A N   1 
ATOM   1401 C CA  . PRO A 1 233 ? 169.899 216.317 173.247 1.00 15.86  ? 240 PRO A CA  1 
ATOM   1402 C C   . PRO A 1 233 ? 168.740 215.348 173.443 1.00 15.91  ? 240 PRO A C   1 
ATOM   1403 O O   . PRO A 1 233 ? 168.276 215.168 174.565 1.00 17.12  ? 240 PRO A O   1 
ATOM   1404 C CB  . PRO A 1 233 ? 169.437 217.758 173.406 1.00 17.97  ? 240 PRO A CB  1 
ATOM   1405 C CG  . PRO A 1 233 ? 169.131 218.217 172.019 1.00 19.88  ? 240 PRO A CG  1 
ATOM   1406 C CD  . PRO A 1 233 ? 170.127 217.527 171.140 1.00 18.58  ? 240 PRO A CD  1 
ATOM   1407 N N   . SER A 1 234 ? 168.217 214.783 172.359 1.00 16.09  ? 241 SER A N   1 
ATOM   1408 C CA  . SER A 1 234 ? 167.090 213.872 172.460 1.00 13.53  ? 241 SER A CA  1 
ATOM   1409 C C   . SER A 1 234 ? 167.411 212.642 171.655 1.00 12.47  ? 241 SER A C   1 
ATOM   1410 O O   . SER A 1 234 ? 167.302 212.638 170.431 1.00 13.76  ? 241 SER A O   1 
ATOM   1411 C CB  . SER A 1 234 ? 165.841 214.526 171.945 1.00 14.68  ? 241 SER A CB  1 
ATOM   1412 O OG  . SER A 1 234 ? 164.761 213.652 172.017 1.00 16.45  ? 241 SER A OG  1 
ATOM   1413 N N   . VAL A 1 235 ? 167.830 211.607 172.359 1.00 12.65  ? 242 VAL A N   1 
ATOM   1414 C CA  . VAL A 1 235 ? 168.337 210.379 171.780 1.00 11.16  ? 242 VAL A CA  1 
ATOM   1415 C C   . VAL A 1 235 ? 167.596 209.185 172.297 1.00 10.74  ? 242 VAL A C   1 
ATOM   1416 O O   . VAL A 1 235 ? 167.419 209.078 173.485 1.00 12.83  ? 242 VAL A O   1 
ATOM   1417 C CB  . VAL A 1 235 ? 169.829 210.234 172.150 1.00 10.10  ? 242 VAL A CB  1 
ATOM   1418 C CG1 . VAL A 1 235 ? 170.433 208.936 171.599 1.00 9.03   ? 242 VAL A CG1 1 
ATOM   1419 C CG2 . VAL A 1 235 ? 170.559 211.420 171.625 1.00 11.83  ? 242 VAL A CG2 1 
ATOM   1420 N N   . SER A 1 236 ? 167.195 208.282 171.425 1.00 11.01  ? 243 SER A N   1 
ATOM   1421 C CA  . SER A 1 236 ? 166.534 207.056 171.846 1.00 9.93   ? 243 SER A CA  1 
ATOM   1422 C C   . SER A 1 236 ? 167.282 205.852 171.326 1.00 9.50   ? 243 SER A C   1 
ATOM   1423 O O   . SER A 1 236 ? 168.101 205.946 170.418 1.00 10.18  ? 243 SER A O   1 
ATOM   1424 C CB  . SER A 1 236 ? 165.107 207.008 171.372 1.00 12.91  ? 243 SER A CB  1 
ATOM   1425 O OG  . SER A 1 236 ? 165.019 206.978 169.991 1.00 14.13  ? 243 SER A OG  1 
ATOM   1426 N N   . THR A 1 237 ? 167.024 204.703 171.903 1.00 11.52  ? 244 THR A N   1 
ATOM   1427 C CA  . THR A 1 237 ? 167.648 203.474 171.437 1.00 10.98  ? 244 THR A CA  1 
ATOM   1428 C C   . THR A 1 237 ? 166.639 202.662 170.693 1.00 12.44  ? 244 THR A C   1 
ATOM   1429 O O   . THR A 1 237 ? 165.516 202.480 171.157 1.00 14.82  ? 244 THR A O   1 
ATOM   1430 C CB  . THR A 1 237 ? 168.252 202.645 172.589 1.00 11.40  ? 244 THR A CB  1 
ATOM   1431 O OG1 . THR A 1 237 ? 169.264 203.401 173.221 1.00 16.79  ? 244 THR A OG1 1 
ATOM   1432 C CG2 . THR A 1 237 ? 168.871 201.382 172.067 1.00 12.25  ? 244 THR A CG2 1 
ATOM   1433 N N   . VAL A 1 238 ? 167.017 202.185 169.521 1.00 13.40  ? 245 VAL A N   1 
ATOM   1434 C CA  . VAL A 1 238 ? 166.103 201.379 168.745 1.00 14.78  ? 245 VAL A CA  1 
ATOM   1435 C C   . VAL A 1 238 ? 166.721 200.047 168.426 1.00 16.93  ? 245 VAL A C   1 
ATOM   1436 O O   . VAL A 1 238 ? 167.936 199.926 168.273 1.00 16.13  ? 245 VAL A O   1 
ATOM   1437 C CB  . VAL A 1 238 ? 165.706 202.092 167.432 1.00 15.10  ? 245 VAL A CB  1 
ATOM   1438 C CG1 . VAL A 1 238 ? 165.008 203.372 167.758 1.00 15.12  ? 245 VAL A CG1 1 
ATOM   1439 C CG2 . VAL A 1 238 ? 166.926 202.358 166.547 1.00 14.00  ? 245 VAL A CG2 1 
ATOM   1440 N N   . GLN A 1 239 ? 165.875 199.046 168.292 1.00 21.90  ? 246 GLN A N   1 
ATOM   1441 C CA  . GLN A 1 239 ? 166.354 197.725 167.907 1.00 24.85  ? 246 GLN A CA  1 
ATOM   1442 C C   . GLN A 1 239 ? 166.844 197.601 166.449 1.00 22.11  ? 246 GLN A C   1 
ATOM   1443 O O   . GLN A 1 239 ? 167.797 196.848 166.183 1.00 21.62  ? 246 GLN A O   1 
ATOM   1444 C CB  . GLN A 1 239 ? 165.243 196.691 168.118 1.00 28.79  ? 246 GLN A CB  1 
ATOM   1445 C CG  . GLN A 1 239 ? 164.887 196.413 169.555 1.00 33.57  ? 246 GLN A CG  1 
ATOM   1446 C CD  . GLN A 1 239 ? 163.731 195.436 169.658 1.00 39.18  ? 246 GLN A CD  1 
ATOM   1447 O OE1 . GLN A 1 239 ? 162.902 195.366 168.743 1.00 39.81  ? 246 GLN A OE1 1 
ATOM   1448 N NE2 . GLN A 1 239 ? 163.666 194.689 170.750 1.00 45.77  ? 246 GLN A NE2 1 
ATOM   1449 N N   . CYS A 1 240 ? 166.162 198.321 165.524 1.00 22.28  ? 247 CYS A N   1 
ATOM   1450 C CA  . CYS A 1 240 ? 166.334 198.240 164.087 1.00 19.42  ? 247 CYS A CA  1 
ATOM   1451 C C   . CYS A 1 240 ? 165.852 199.584 163.522 1.00 19.06  ? 247 CYS A C   1 
ATOM   1452 O O   . CYS A 1 240 ? 164.973 200.225 164.119 1.00 20.21  ? 247 CYS A O   1 
ATOM   1453 C CB  . CYS A 1 240 ? 165.513 197.016 163.570 1.00 21.14  ? 247 CYS A CB  1 
ATOM   1454 S SG  . CYS A 1 240 ? 165.903 196.448 161.977 1.00 39.58  ? 247 CYS A SG  1 
ATOM   1455 N N   . THR A 1 241 ? 166.414 200.013 162.393 1.00 17.89  ? 248 THR A N   1 
ATOM   1456 C CA  . THR A 1 241 ? 166.053 201.293 161.770 1.00 15.55  ? 248 THR A CA  1 
ATOM   1457 C C   . THR A 1 241 ? 164.696 201.224 161.106 1.00 16.94  ? 248 THR A C   1 
ATOM   1458 O O   . THR A 1 241 ? 164.122 200.144 160.944 1.00 19.54  ? 248 THR A O   1 
ATOM   1459 C CB  . THR A 1 241 ? 166.999 201.713 160.628 1.00 13.35  ? 248 THR A CB  1 
ATOM   1460 O OG1 . THR A 1 241 ? 166.832 200.818 159.526 1.00 17.48  ? 248 THR A OG1 1 
ATOM   1461 C CG2 . THR A 1 241 ? 168.428 201.680 161.074 1.00 12.45  ? 248 THR A CG2 1 
ATOM   1462 N N   . HIS A 1 242 ? 164.191 202.390 160.707 1.00 16.69  ? 249 HIS A N   1 
ATOM   1463 C CA  . HIS A 1 242 ? 162.946 202.479 159.962 1.00 15.95  ? 249 HIS A CA  1 
ATOM   1464 C C   . HIS A 1 242 ? 163.218 201.873 158.614 1.00 17.99  ? 249 HIS A C   1 
ATOM   1465 O O   . HIS A 1 242 ? 164.375 201.567 158.289 1.00 22.41  ? 249 HIS A O   1 
ATOM   1466 C CB  . HIS A 1 242 ? 162.423 203.929 159.792 1.00 16.58  ? 249 HIS A CB  1 
ATOM   1467 C CG  . HIS A 1 242 ? 163.195 204.877 158.821 1.00 16.92  ? 249 HIS A CG  1 
ATOM   1468 N ND1 . HIS A 1 242 ? 164.385 205.466 159.149 1.00 17.07  ? 249 HIS A ND1 1 
ATOM   1469 C CD2 . HIS A 1 242 ? 162.886 205.339 157.580 1.00 18.91  ? 249 HIS A CD2 1 
ATOM   1470 C CE1 . HIS A 1 242 ? 164.793 206.242 158.142 1.00 16.87  ? 249 HIS A CE1 1 
ATOM   1471 N NE2 . HIS A 1 242 ? 163.904 206.190 157.185 1.00 17.95  ? 249 HIS A NE2 1 
ATOM   1472 N N   . GLY A 1 243 ? 162.172 201.576 157.857 1.00 17.73  ? 250 GLY A N   1 
ATOM   1473 C CA  . GLY A 1 243 ? 162.427 200.999 156.558 1.00 16.56  ? 250 GLY A CA  1 
ATOM   1474 C C   . GLY A 1 243 ? 162.860 202.076 155.604 1.00 17.03  ? 250 GLY A C   1 
ATOM   1475 O O   . GLY A 1 243 ? 162.146 203.052 155.379 1.00 18.34  ? 250 GLY A O   1 
ATOM   1476 N N   . ILE A 1 244 ? 163.989 201.853 154.975 1.00 18.28  ? 251 ILE A N   1 
ATOM   1477 C CA  . ILE A 1 244 ? 164.545 202.782 154.025 1.00 16.04  ? 251 ILE A CA  1 
ATOM   1478 C C   . ILE A 1 244 ? 164.408 202.258 152.629 1.00 17.26  ? 251 ILE A C   1 
ATOM   1479 O O   . ILE A 1 244 ? 164.783 201.129 152.346 1.00 19.66  ? 251 ILE A O   1 
ATOM   1480 C CB  . ILE A 1 244 ? 166.018 203.059 154.363 1.00 16.35  ? 251 ILE A CB  1 
ATOM   1481 C CG1 . ILE A 1 244 ? 166.073 203.718 155.760 1.00 16.59  ? 251 ILE A CG1 1 
ATOM   1482 C CG2 . ILE A 1 244 ? 166.661 203.922 153.288 1.00 17.53  ? 251 ILE A CG2 1 
ATOM   1483 C CD1 . ILE A 1 244 ? 167.424 203.851 156.380 1.00 14.87  ? 251 ILE A CD1 1 
ATOM   1484 N N   . LYS A 1 245 ? 163.802 203.041 151.760 1.00 17.83  ? 252 LYS A N   1 
ATOM   1485 C CA  . LYS A 1 245 ? 163.635 202.602 150.392 1.00 16.29  ? 252 LYS A CA  1 
ATOM   1486 C C   . LYS A 1 245 ? 164.872 202.956 149.600 1.00 16.63  ? 252 LYS A C   1 
ATOM   1487 O O   . LYS A 1 245 ? 165.213 204.136 149.514 1.00 17.16  ? 252 LYS A O   1 
ATOM   1488 C CB  . LYS A 1 245 ? 162.431 203.251 149.747 1.00 17.23  ? 252 LYS A CB  1 
ATOM   1489 C CG  . LYS A 1 245 ? 161.154 202.874 150.364 1.00 18.96  ? 252 LYS A CG  1 
ATOM   1490 C CD  . LYS A 1 245 ? 159.954 203.335 149.540 1.00 20.17  ? 252 LYS A CD  1 
ATOM   1491 C CE  . LYS A 1 245 ? 159.640 204.839 149.681 1.00 20.96  ? 252 LYS A CE  1 
ATOM   1492 N NZ  . LYS A 1 245 ? 159.094 205.184 151.037 1.00 27.53  ? 252 LYS A NZ  1 
ATOM   1493 N N   . PRO A 1 246 ? 165.553 202.006 148.961 1.00 16.83  ? 253 PRO A N   1 
ATOM   1494 C CA  . PRO A 1 246 ? 166.744 202.227 148.187 1.00 15.65  ? 253 PRO A CA  1 
ATOM   1495 C C   . PRO A 1 246 ? 166.385 202.799 146.836 1.00 16.23  ? 253 PRO A C   1 
ATOM   1496 O O   . PRO A 1 246 ? 166.483 202.116 145.818 1.00 16.51  ? 253 PRO A O   1 
ATOM   1497 C CB  . PRO A 1 246 ? 167.336 200.837 148.097 1.00 17.61  ? 253 PRO A CB  1 
ATOM   1498 C CG  . PRO A 1 246 ? 166.147 199.935 148.104 1.00 18.34  ? 253 PRO A CG  1 
ATOM   1499 C CD  . PRO A 1 246 ? 165.157 200.597 149.032 1.00 17.84  ? 253 PRO A CD  1 
ATOM   1500 N N   . VAL A 1 247 ? 165.895 204.024 146.842 1.00 15.12  ? 254 VAL A N   1 
ATOM   1501 C CA  . VAL A 1 247 ? 165.511 204.686 145.620 1.00 12.88  ? 254 VAL A CA  1 
ATOM   1502 C C   . VAL A 1 247 ? 166.797 205.192 145.025 1.00 12.68  ? 254 VAL A C   1 
ATOM   1503 O O   . VAL A 1 247 ? 167.584 205.834 145.714 1.00 15.24  ? 254 VAL A O   1 
ATOM   1504 C CB  . VAL A 1 247 ? 164.549 205.861 145.893 1.00 11.98  ? 254 VAL A CB  1 
ATOM   1505 C CG1 . VAL A 1 247 ? 164.204 206.597 144.611 1.00 10.50  ? 254 VAL A CG1 1 
ATOM   1506 C CG2 . VAL A 1 247 ? 163.300 205.355 146.540 1.00 13.88  ? 254 VAL A CG2 1 
ATOM   1507 N N   . VAL A 1 248 ? 167.032 204.881 143.771 1.00 13.45  ? 255 VAL A N   1 
ATOM   1508 C CA  . VAL A 1 248 ? 168.246 205.304 143.116 1.00 12.07  ? 255 VAL A CA  1 
ATOM   1509 C C   . VAL A 1 248 ? 167.949 206.417 142.136 1.00 12.28  ? 255 VAL A C   1 
ATOM   1510 O O   . VAL A 1 248 ? 167.288 206.193 141.126 1.00 14.11  ? 255 VAL A O   1 
ATOM   1511 C CB  . VAL A 1 248 ? 168.864 204.080 142.391 1.00 12.51  ? 255 VAL A CB  1 
ATOM   1512 C CG1 . VAL A 1 248 ? 170.096 204.433 141.655 1.00 15.18  ? 255 VAL A CG1 1 
ATOM   1513 C CG2 . VAL A 1 248 ? 169.220 203.011 143.416 1.00 14.62  ? 255 VAL A CG2 1 
ATOM   1514 N N   . SER A 1 249 ? 168.468 207.602 142.424 1.00 13.27  ? 256 SER A N   1 
ATOM   1515 C CA  . SER A 1 249 ? 168.283 208.788 141.600 1.00 11.48  ? 256 SER A CA  1 
ATOM   1516 C C   . SER A 1 249 ? 169.453 209.730 141.792 1.00 13.22  ? 256 SER A C   1 
ATOM   1517 O O   . SER A 1 249 ? 170.172 209.640 142.786 1.00 16.50  ? 256 SER A O   1 
ATOM   1518 C CB  . SER A 1 249 ? 167.020 209.560 141.949 1.00 10.30  ? 256 SER A CB  1 
ATOM   1519 O OG  . SER A 1 249 ? 167.129 210.161 143.218 1.00 11.48  ? 256 SER A OG  1 
ATOM   1520 N N   . THR A 1 250 ? 169.595 210.695 140.891 1.00 12.60  ? 257 THR A N   1 
ATOM   1521 C CA  . THR A 1 250 ? 170.697 211.657 141.028 1.00 13.34  ? 257 THR A CA  1 
ATOM   1522 C C   . THR A 1 250 ? 170.397 212.979 141.724 1.00 15.49  ? 257 THR A C   1 
ATOM   1523 O O   . THR A 1 250 ? 170.449 213.074 142.943 1.00 17.05  ? 257 THR A O   1 
ATOM   1524 C CB  . THR A 1 250 ? 171.343 211.988 139.672 1.00 14.43  ? 257 THR A CB  1 
ATOM   1525 O OG1 . THR A 1 250 ? 170.326 212.463 138.734 1.00 13.74  ? 257 THR A OG1 1 
ATOM   1526 C CG2 . THR A 1 250 ? 172.042 210.784 139.152 1.00 15.56  ? 257 THR A CG2 1 
ATOM   1527 N N   . GLN A 1 251 ? 170.159 214.016 140.960 1.00 13.82  ? 258 GLN A N   1 
ATOM   1528 C CA  . GLN A 1 251 ? 170.024 215.353 141.538 1.00 11.57  ? 258 GLN A CA  1 
ATOM   1529 C C   . GLN A 1 251 ? 168.782 215.688 142.366 1.00 10.82  ? 258 GLN A C   1 
ATOM   1530 O O   . GLN A 1 251 ? 168.819 216.612 143.185 1.00 11.10  ? 258 GLN A O   1 
ATOM   1531 C CB  . GLN A 1 251 ? 170.253 216.371 140.453 1.00 11.93  ? 258 GLN A CB  1 
ATOM   1532 C CG  . GLN A 1 251 ? 169.334 216.328 139.358 1.00 10.94  ? 258 GLN A CG  1 
ATOM   1533 C CD  . GLN A 1 251 ? 169.658 217.337 138.398 1.00 11.43  ? 258 GLN A CD  1 
ATOM   1534 O OE1 . GLN A 1 251 ? 169.080 218.401 138.510 1.00 15.92  ? 258 GLN A OE1 1 
ATOM   1535 N NE2 . GLN A 1 251 ? 170.571 217.096 137.472 1.00 11.29  ? 258 GLN A NE2 1 
ATOM   1536 N N   . LEU A 1 252 ? 167.687 214.971 142.182 1.00 10.41  ? 259 LEU A N   1 
ATOM   1537 C CA  . LEU A 1 252 ? 166.505 215.198 142.998 1.00 7.67   ? 259 LEU A CA  1 
ATOM   1538 C C   . LEU A 1 252 ? 166.260 213.890 143.721 1.00 7.82   ? 259 LEU A C   1 
ATOM   1539 O O   . LEU A 1 252 ? 166.159 212.813 143.092 1.00 11.49  ? 259 LEU A O   1 
ATOM   1540 C CB  . LEU A 1 252 ? 165.266 215.573 142.178 1.00 5.76   ? 259 LEU A CB  1 
ATOM   1541 C CG  . LEU A 1 252 ? 165.365 216.757 141.205 1.00 5.37   ? 259 LEU A CG  1 
ATOM   1542 C CD1 . LEU A 1 252 ? 164.105 216.837 140.416 1.00 2.62   ? 259 LEU A CD1 1 
ATOM   1543 C CD2 . LEU A 1 252 ? 165.579 218.026 141.931 1.00 8.99   ? 259 LEU A CD2 1 
ATOM   1544 N N   . LEU A 1 253 ? 166.147 213.980 145.031 1.00 9.57   ? 260 LEU A N   1 
ATOM   1545 C CA  . LEU A 1 253 ? 165.909 212.824 145.859 1.00 9.57   ? 260 LEU A CA  1 
ATOM   1546 C C   . LEU A 1 253 ? 164.439 212.587 145.880 1.00 8.72   ? 260 LEU A C   1 
ATOM   1547 O O   . LEU A 1 253 ? 163.664 213.504 146.139 1.00 9.37   ? 260 LEU A O   1 
ATOM   1548 C CB  . LEU A 1 253 ? 166.425 213.070 147.273 1.00 8.87   ? 260 LEU A CB  1 
ATOM   1549 C CG  . LEU A 1 253 ? 167.918 213.279 147.414 1.00 9.58   ? 260 LEU A CG  1 
ATOM   1550 C CD1 . LEU A 1 253 ? 168.234 213.738 148.797 1.00 12.93  ? 260 LEU A CD1 1 
ATOM   1551 C CD2 . LEU A 1 253 ? 168.615 211.999 147.165 1.00 12.89  ? 260 LEU A CD2 1 
ATOM   1552 N N   . LEU A 1 254 ? 164.047 211.380 145.551 1.00 10.76  ? 261 LEU A N   1 
ATOM   1553 C CA  . LEU A 1 254 ? 162.644 211.070 145.479 1.00 9.54   ? 261 LEU A CA  1 
ATOM   1554 C C   . LEU A 1 254 ? 162.237 210.120 146.579 1.00 10.91  ? 261 LEU A C   1 
ATOM   1555 O O   . LEU A 1 254 ? 163.063 209.329 147.038 1.00 13.98  ? 261 LEU A O   1 
ATOM   1556 C CB  . LEU A 1 254 ? 162.327 210.444 144.117 1.00 9.28   ? 261 LEU A CB  1 
ATOM   1557 C CG  . LEU A 1 254 ? 162.680 211.265 142.870 1.00 7.89   ? 261 LEU A CG  1 
ATOM   1558 C CD1 . LEU A 1 254 ? 162.420 210.409 141.674 1.00 9.26   ? 261 LEU A CD1 1 
ATOM   1559 C CD2 . LEU A 1 254 ? 161.860 212.558 142.818 1.00 7.52   ? 261 LEU A CD2 1 
ATOM   1560 N N   . ASN A 1 255 ? 160.977 210.252 147.035 1.00 11.26  ? 262 ASN A N   1 
ATOM   1561 C CA  . ASN A 1 255 ? 160.253 209.375 147.961 1.00 12.34  ? 262 ASN A CA  1 
ATOM   1562 C C   . ASN A 1 255 ? 161.001 209.097 149.286 1.00 14.74  ? 262 ASN A C   1 
ATOM   1563 O O   . ASN A 1 255 ? 160.917 207.985 149.828 1.00 17.64  ? 262 ASN A O   1 
ATOM   1564 C CB  . ASN A 1 255 ? 159.883 208.063 147.246 1.00 13.72  ? 262 ASN A CB  1 
ATOM   1565 C CG  . ASN A 1 255 ? 158.853 208.191 146.090 1.00 14.02  ? 262 ASN A CG  1 
ATOM   1566 O OD1 . ASN A 1 255 ? 158.242 209.258 145.836 1.00 15.54  ? 262 ASN A OD1 1 
ATOM   1567 N ND2 . ASN A 1 255 ? 158.664 207.057 145.413 1.00 15.77  ? 262 ASN A ND2 1 
ATOM   1568 N N   . GLY A 1 256 ? 161.687 210.101 149.869 1.00 14.20  ? 263 GLY A N   1 
ATOM   1569 C CA  . GLY A 1 256 ? 162.420 209.977 151.128 1.00 15.51  ? 263 GLY A CA  1 
ATOM   1570 C C   . GLY A 1 256 ? 161.637 210.581 152.257 1.00 16.52  ? 263 GLY A C   1 
ATOM   1571 O O   . GLY A 1 256 ? 160.432 210.826 152.141 1.00 17.97  ? 263 GLY A O   1 
ATOM   1572 N N   . SER A 1 257 ? 162.323 210.819 153.353 1.00 17.43  ? 264 SER A N   1 
ATOM   1573 C CA  . SER A 1 257 ? 161.701 211.411 154.508 1.00 17.88  ? 264 SER A CA  1 
ATOM   1574 C C   . SER A 1 257 ? 161.748 212.917 154.386 1.00 15.80  ? 264 SER A C   1 
ATOM   1575 O O   . SER A 1 257 ? 162.724 213.482 153.893 1.00 15.76  ? 264 SER A O   1 
ATOM   1576 C CB  . SER A 1 257 ? 162.415 210.977 155.769 1.00 18.92  ? 264 SER A CB  1 
ATOM   1577 O OG  . SER A 1 257 ? 162.292 209.595 155.983 1.00 20.78  ? 264 SER A OG  1 
ATOM   1578 N N   . LEU A 1 258 ? 160.724 213.570 154.888 1.00 16.24  ? 265 LEU A N   1 
ATOM   1579 C CA  . LEU A 1 258 ? 160.668 215.022 154.936 1.00 17.03  ? 265 LEU A CA  1 
ATOM   1580 C C   . LEU A 1 258 ? 161.077 215.537 156.279 1.00 16.86  ? 265 LEU A C   1 
ATOM   1581 O O   . LEU A 1 258 ? 160.957 214.834 157.280 1.00 19.50  ? 265 LEU A O   1 
ATOM   1582 C CB  . LEU A 1 258 ? 159.270 215.518 154.623 1.00 17.19  ? 265 LEU A CB  1 
ATOM   1583 C CG  . LEU A 1 258 ? 158.739 215.232 153.256 1.00 15.93  ? 265 LEU A CG  1 
ATOM   1584 C CD1 . LEU A 1 258 ? 157.327 215.585 153.232 1.00 18.76  ? 265 LEU A CD1 1 
ATOM   1585 C CD2 . LEU A 1 258 ? 159.465 216.112 152.229 1.00 15.10  ? 265 LEU A CD2 1 
ATOM   1586 N N   . ALA A 1 259 ? 161.573 216.757 156.286 1.00 16.73  ? 266 ALA A N   1 
ATOM   1587 C CA  . ALA A 1 259 ? 161.931 217.440 157.504 1.00 17.95  ? 266 ALA A CA  1 
ATOM   1588 C C   . ALA A 1 259 ? 160.652 217.711 158.257 1.00 22.82  ? 266 ALA A C   1 
ATOM   1589 O O   . ALA A 1 259 ? 159.611 217.935 157.645 1.00 22.91  ? 266 ALA A O   1 
ATOM   1590 C CB  . ALA A 1 259 ? 162.691 218.710 157.202 1.00 16.54  ? 266 ALA A CB  1 
ATOM   1591 N N   . GLU A 1 260 ? 160.705 217.646 159.578 1.00 27.25  ? 267 GLU A N   1 
ATOM   1592 C CA  . GLU A 1 260 ? 159.531 217.872 160.408 1.00 27.44  ? 267 GLU A CA  1 
ATOM   1593 C C   . GLU A 1 260 ? 159.032 219.308 160.443 1.00 28.59  ? 267 GLU A C   1 
ATOM   1594 O O   . GLU A 1 260 ? 157.830 219.547 160.526 1.00 29.14  ? 267 GLU A O   1 
ATOM   1595 C CB  . GLU A 1 260 ? 159.818 217.426 161.833 1.00 31.93  ? 267 GLU A CB  1 
ATOM   1596 C CG  . GLU A 1 260 ? 160.084 215.933 162.003 1.00 32.87  ? 267 GLU A CG  1 
ATOM   1597 C CD  . GLU A 1 260 ? 161.520 215.538 161.699 1.00 31.66  ? 267 GLU A CD  1 
ATOM   1598 O OE1 . GLU A 1 260 ? 162.293 216.399 161.326 1.00 29.66  ? 267 GLU A OE1 1 
ATOM   1599 O OE2 . GLU A 1 260 ? 161.847 214.389 161.863 1.00 36.84  ? 267 GLU A OE2 1 
ATOM   1600 N N   . GLU A 1 261 ? 159.951 220.264 160.438 1.00 27.16  ? 268 GLU A N   1 
ATOM   1601 C CA  . GLU A 1 261 ? 159.560 221.662 160.569 1.00 27.29  ? 268 GLU A CA  1 
ATOM   1602 C C   . GLU A 1 261 ? 160.047 222.597 159.467 1.00 26.38  ? 268 GLU A C   1 
ATOM   1603 O O   . GLU A 1 261 ? 159.265 223.377 158.927 1.00 26.28  ? 268 GLU A O   1 
ATOM   1604 C CB  . GLU A 1 261 ? 160.080 222.191 161.906 1.00 33.80  ? 268 GLU A CB  1 
ATOM   1605 C CG  . GLU A 1 261 ? 159.497 221.507 163.137 1.00 34.90  ? 268 GLU A CG  1 
ATOM   1606 C CD  . GLU A 1 261 ? 160.062 222.028 164.432 1.00 39.19  ? 268 GLU A CD  1 
ATOM   1607 O OE1 . GLU A 1 261 ? 161.002 222.789 164.386 1.00 40.93  ? 268 GLU A OE1 1 
ATOM   1608 O OE2 . GLU A 1 261 ? 159.544 221.681 165.469 1.00 40.90  ? 268 GLU A OE2 1 
ATOM   1609 N N   . GLU A 1 262 ? 161.338 222.539 159.159 1.00 25.41  ? 269 GLU A N   1 
ATOM   1610 C CA  . GLU A 1 262 ? 161.998 223.486 158.261 1.00 23.49  ? 269 GLU A CA  1 
ATOM   1611 C C   . GLU A 1 262 ? 162.843 222.780 157.240 1.00 19.61  ? 269 GLU A C   1 
ATOM   1612 O O   . GLU A 1 262 ? 163.197 221.626 157.423 1.00 21.54  ? 269 GLU A O   1 
ATOM   1613 C CB  . GLU A 1 262 ? 162.901 224.454 159.027 1.00 25.86  ? 269 GLU A CB  1 
ATOM   1614 C CG  . GLU A 1 262 ? 162.211 225.355 160.025 1.00 32.15  ? 269 GLU A CG  1 
ATOM   1615 C CD  . GLU A 1 262 ? 163.174 226.317 160.757 1.00 38.57  ? 269 GLU A CD  1 
ATOM   1616 O OE1 . GLU A 1 262 ? 164.259 226.595 160.270 1.00 34.63  ? 269 GLU A OE1 1 
ATOM   1617 O OE2 . GLU A 1 262 ? 162.814 226.747 161.837 1.00 46.15  ? 269 GLU A OE2 1 
ATOM   1618 N N   . VAL A 1 263 ? 163.167 223.469 156.165 1.00 18.36  ? 270 VAL A N   1 
ATOM   1619 C CA  . VAL A 1 263 ? 164.100 222.916 155.208 1.00 15.66  ? 270 VAL A CA  1 
ATOM   1620 C C   . VAL A 1 263 ? 165.461 222.831 155.893 1.00 14.52  ? 270 VAL A C   1 
ATOM   1621 O O   . VAL A 1 263 ? 165.904 223.781 156.533 1.00 17.16  ? 270 VAL A O   1 
ATOM   1622 C CB  . VAL A 1 263 ? 164.153 223.818 153.955 1.00 14.32  ? 270 VAL A CB  1 
ATOM   1623 C CG1 . VAL A 1 263 ? 165.225 223.375 152.999 1.00 13.10  ? 270 VAL A CG1 1 
ATOM   1624 C CG2 . VAL A 1 263 ? 162.814 223.769 153.262 1.00 15.37  ? 270 VAL A CG2 1 
ATOM   1625 N N   . ILE A 1 264 ? 166.125 221.690 155.805 1.00 13.90  ? 271 ILE A N   1 
ATOM   1626 C CA  . ILE A 1 264 ? 167.416 221.551 156.475 1.00 13.02  ? 271 ILE A CA  1 
ATOM   1627 C C   . ILE A 1 264 ? 168.547 221.394 155.497 1.00 11.73  ? 271 ILE A C   1 
ATOM   1628 O O   . ILE A 1 264 ? 168.547 220.498 154.660 1.00 12.76  ? 271 ILE A O   1 
ATOM   1629 C CB  . ILE A 1 264 ? 167.438 220.373 157.473 1.00 13.07  ? 271 ILE A CB  1 
ATOM   1630 C CG1 . ILE A 1 264 ? 166.381 220.595 158.549 1.00 14.90  ? 271 ILE A CG1 1 
ATOM   1631 C CG2 . ILE A 1 264 ? 168.844 220.252 158.109 1.00 13.28  ? 271 ILE A CG2 1 
ATOM   1632 C CD1 . ILE A 1 264 ? 166.122 219.410 159.437 1.00 17.29  ? 271 ILE A CD1 1 
ATOM   1633 N N   . ILE A 1 265 ? 169.544 222.244 155.628 1.00 12.50  ? 272 ILE A N   1 
ATOM   1634 C CA  . ILE A 1 265 ? 170.682 222.167 154.742 1.00 11.96  ? 272 ILE A CA  1 
ATOM   1635 C C   . ILE A 1 265 ? 171.870 221.542 155.438 1.00 12.71  ? 272 ILE A C   1 
ATOM   1636 O O   . ILE A 1 265 ? 172.370 222.066 156.425 1.00 15.81  ? 272 ILE A O   1 
ATOM   1637 C CB  . ILE A 1 265 ? 171.010 223.552 154.188 1.00 11.24  ? 272 ILE A CB  1 
ATOM   1638 C CG1 . ILE A 1 265 ? 169.776 224.020 153.408 1.00 11.81  ? 272 ILE A CG1 1 
ATOM   1639 C CG2 . ILE A 1 265 ? 172.232 223.512 153.362 1.00 12.74  ? 272 ILE A CG2 1 
ATOM   1640 C CD1 . ILE A 1 265 ? 169.850 225.361 152.857 1.00 13.91  ? 272 ILE A CD1 1 
ATOM   1641 N N   . ARG A 1 266 ? 172.322 220.414 154.912 1.00 12.54  ? 273 ARG A N   1 
ATOM   1642 C CA  . ARG A 1 266 ? 173.396 219.658 155.519 1.00 12.23  ? 273 ARG A CA  1 
ATOM   1643 C C   . ARG A 1 266 ? 174.628 219.580 154.626 1.00 12.42  ? 273 ARG A C   1 
ATOM   1644 O O   . ARG A 1 266 ? 174.551 219.221 153.457 1.00 14.24  ? 273 ARG A O   1 
ATOM   1645 C CB  . ARG A 1 266 ? 172.919 218.240 155.801 1.00 12.17  ? 273 ARG A CB  1 
ATOM   1646 C CG  . ARG A 1 266 ? 171.748 218.161 156.715 1.00 12.32  ? 273 ARG A CG  1 
ATOM   1647 C CD  . ARG A 1 266 ? 171.471 216.793 157.186 1.00 12.45  ? 273 ARG A CD  1 
ATOM   1648 N NE  . ARG A 1 266 ? 170.364 216.775 158.122 1.00 12.96  ? 273 ARG A NE  1 
ATOM   1649 C CZ  . ARG A 1 266 ? 169.082 216.581 157.826 1.00 12.02  ? 273 ARG A CZ  1 
ATOM   1650 N NH1 . ARG A 1 266 ? 168.682 216.322 156.630 1.00 12.39  ? 273 ARG A NH1 1 
ATOM   1651 N NH2 . ARG A 1 266 ? 168.177 216.659 158.758 1.00 12.96  ? 273 ARG A NH2 1 
ATOM   1652 N N   . SER A 1 267 ? 175.781 219.883 155.178 1.00 15.15  ? 274 SER A N   1 
ATOM   1653 C CA  . SER A 1 267 ? 177.019 219.793 154.415 1.00 14.32  ? 274 SER A CA  1 
ATOM   1654 C C   . SER A 1 267 ? 178.161 219.440 155.326 1.00 15.70  ? 274 SER A C   1 
ATOM   1655 O O   . SER A 1 267 ? 178.234 219.944 156.443 1.00 19.36  ? 274 SER A O   1 
ATOM   1656 C CB  . SER A 1 267 ? 177.333 221.070 153.705 1.00 16.30  ? 274 SER A CB  1 
ATOM   1657 O OG  . SER A 1 267 ? 178.541 220.924 153.016 1.00 19.06  ? 274 SER A OG  1 
ATOM   1658 N N   . GLU A 1 268 ? 179.064 218.578 154.871 1.00 15.55  ? 275 GLU A N   1 
ATOM   1659 C CA  . GLU A 1 268 ? 180.211 218.195 155.700 1.00 16.77  ? 275 GLU A CA  1 
ATOM   1660 C C   . GLU A 1 268 ? 181.045 219.407 156.149 1.00 20.59  ? 275 GLU A C   1 
ATOM   1661 O O   . GLU A 1 268 ? 181.515 219.452 157.290 1.00 23.38  ? 275 GLU A O   1 
ATOM   1662 C CB  . GLU A 1 268 ? 181.082 217.185 154.951 1.00 17.79  ? 275 GLU A CB  1 
ATOM   1663 C CG  . GLU A 1 268 ? 182.227 216.631 155.756 1.00 19.80  ? 275 GLU A CG  1 
ATOM   1664 C CD  . GLU A 1 268 ? 183.013 215.583 155.015 1.00 23.38  ? 275 GLU A CD  1 
ATOM   1665 O OE1 . GLU A 1 268 ? 182.669 215.275 153.885 1.00 22.72  ? 275 GLU A OE1 1 
ATOM   1666 O OE2 . GLU A 1 268 ? 183.974 215.097 155.558 1.00 28.97  ? 275 GLU A OE2 1 
ATOM   1667 N N   . ASN A 1 269 ? 181.239 220.370 155.228 1.00 23.22  ? 276 ASN A N   1 
ATOM   1668 C CA  . ASN A 1 269 ? 181.931 221.642 155.388 1.00 21.96  ? 276 ASN A CA  1 
ATOM   1669 C C   . ASN A 1 269 ? 181.261 222.627 154.415 1.00 21.77  ? 276 ASN A C   1 
ATOM   1670 O O   . ASN A 1 269 ? 181.526 222.604 153.213 1.00 26.62  ? 276 ASN A O   1 
ATOM   1671 C CB  . ASN A 1 269 ? 183.450 221.479 155.154 1.00 24.80  ? 276 ASN A CB  1 
ATOM   1672 C CG  . ASN A 1 269 ? 184.300 222.755 155.456 1.00 28.45  ? 276 ASN A CG  1 
ATOM   1673 O OD1 . ASN A 1 269 ? 183.756 223.875 155.496 1.00 29.47  ? 276 ASN A OD1 1 
ATOM   1674 N ND2 . ASN A 1 269 ? 185.612 222.581 155.647 1.00 31.81  ? 276 ASN A ND2 1 
ATOM   1675 N N   . ILE A 1 270 ? 180.344 223.490 154.917 1.00 21.65  ? 277 ILE A N   1 
ATOM   1676 C CA  . ILE A 1 270 ? 179.492 224.364 154.080 1.00 23.06  ? 277 ILE A CA  1 
ATOM   1677 C C   . ILE A 1 270 ? 180.262 225.416 153.267 1.00 24.12  ? 277 ILE A C   1 
ATOM   1678 O O   . ILE A 1 270 ? 179.843 225.780 152.162 1.00 26.74  ? 277 ILE A O   1 
ATOM   1679 C CB  . ILE A 1 270 ? 178.368 224.990 154.946 1.00 22.67  ? 277 ILE A CB  1 
ATOM   1680 C CG1 . ILE A 1 270 ? 177.214 225.610 154.087 1.00 21.58  ? 277 ILE A CG1 1 
ATOM   1681 C CG2 . ILE A 1 270 ? 178.894 226.033 155.882 1.00 25.53  ? 277 ILE A CG2 1 
ATOM   1682 C CD1 . ILE A 1 270 ? 176.367 224.639 153.269 1.00 18.18  ? 277 ILE A CD1 1 
ATOM   1683 N N   . THR A 1 271 ? 181.418 225.851 153.763 1.00 26.75  ? 278 THR A N   1 
ATOM   1684 C CA  . THR A 1 271 ? 182.198 226.855 153.061 1.00 27.52  ? 278 THR A CA  1 
ATOM   1685 C C   . THR A 1 271 ? 183.151 226.243 152.037 1.00 28.56  ? 278 THR A C   1 
ATOM   1686 O O   . THR A 1 271 ? 183.771 226.974 151.258 1.00 29.65  ? 278 THR A O   1 
ATOM   1687 C CB  . THR A 1 271 ? 183.014 227.718 154.035 1.00 28.84  ? 278 THR A CB  1 
ATOM   1688 O OG1 . THR A 1 271 ? 183.972 226.909 154.716 1.00 29.43  ? 278 THR A OG1 1 
ATOM   1689 C CG2 . THR A 1 271 ? 182.087 228.342 155.054 1.00 29.70  ? 278 THR A CG2 1 
ATOM   1690 N N   . ASN A 1 272 ? 183.242 224.920 152.011 1.00 27.21  ? 279 ASN A N   1 
ATOM   1691 C CA  . ASN A 1 272 ? 184.114 224.178 151.120 1.00 25.19  ? 279 ASN A CA  1 
ATOM   1692 C C   . ASN A 1 272 ? 183.355 223.872 149.828 1.00 26.81  ? 279 ASN A C   1 
ATOM   1693 O O   . ASN A 1 272 ? 182.349 223.167 149.833 1.00 29.51  ? 279 ASN A O   1 
ATOM   1694 C CB  . ASN A 1 272 ? 184.610 222.926 151.792 1.00 26.32  ? 279 ASN A CB  1 
ATOM   1695 C CG  . ASN A 1 272 ? 185.621 222.211 151.025 1.00 26.44  ? 279 ASN A CG  1 
ATOM   1696 O OD1 . ASN A 1 272 ? 185.700 222.320 149.803 1.00 27.49  ? 279 ASN A OD1 1 
ATOM   1697 N ND2 . ASN A 1 272 ? 186.432 221.449 151.712 1.00 26.79  ? 279 ASN A ND2 1 
ATOM   1698 N N   . ASN A 1 273 ? 183.790 224.411 148.701 1.00 28.79  ? 280 ASN A N   1 
ATOM   1699 C CA  . ASN A 1 273 ? 183.022 224.229 147.472 1.00 27.87  ? 280 ASN A CA  1 
ATOM   1700 C C   . ASN A 1 273 ? 183.286 222.877 146.809 1.00 27.70  ? 280 ASN A C   1 
ATOM   1701 O O   . ASN A 1 273 ? 182.767 222.578 145.740 1.00 29.22  ? 280 ASN A O   1 
ATOM   1702 C CB  . ASN A 1 273 ? 183.284 225.376 146.518 1.00 30.78  ? 280 ASN A CB  1 
ATOM   1703 C CG  . ASN A 1 273 ? 184.702 225.448 146.117 1.00 32.81  ? 280 ASN A CG  1 
ATOM   1704 O OD1 . ASN A 1 273 ? 185.543 224.826 146.785 1.00 31.93  ? 280 ASN A OD1 1 
ATOM   1705 N ND2 . ASN A 1 273 ? 185.019 226.179 145.071 1.00 36.08  ? 280 ASN A ND2 1 
ATOM   1706 N N   . ALA A 1 274 ? 184.087 222.046 147.456 1.00 27.11  ? 281 ALA A N   1 
ATOM   1707 C CA  . ALA A 1 274 ? 184.351 220.704 146.982 1.00 26.12  ? 281 ALA A CA  1 
ATOM   1708 C C   . ALA A 1 274 ? 183.368 219.712 147.589 1.00 26.08  ? 281 ALA A C   1 
ATOM   1709 O O   . ALA A 1 274 ? 183.424 218.520 147.288 1.00 25.51  ? 281 ALA A O   1 
ATOM   1710 C CB  . ALA A 1 274 ? 185.761 220.281 147.319 1.00 28.38  ? 281 ALA A CB  1 
ATOM   1711 N N   . LYS A 1 275 ? 182.496 220.185 148.480 1.00 25.92  ? 282 LYS A N   1 
ATOM   1712 C CA  . LYS A 1 275 ? 181.542 219.317 149.151 1.00 21.98  ? 282 LYS A CA  1 
ATOM   1713 C C   . LYS A 1 275 ? 180.137 219.481 148.613 1.00 21.70  ? 282 LYS A C   1 
ATOM   1714 O O   . LYS A 1 275 ? 179.770 220.526 148.082 1.00 22.32  ? 282 LYS A O   1 
ATOM   1715 C CB  . LYS A 1 275 ? 181.563 219.587 150.649 1.00 21.76  ? 282 LYS A CB  1 
ATOM   1716 C CG  . LYS A 1 275 ? 182.903 219.359 151.339 1.00 22.17  ? 282 LYS A CG  1 
ATOM   1717 C CD  . LYS A 1 275 ? 183.300 217.904 151.310 1.00 20.46  ? 282 LYS A CD  1 
ATOM   1718 C CE  . LYS A 1 275 ? 184.509 217.644 152.149 1.00 22.92  ? 282 LYS A CE  1 
ATOM   1719 N NZ  . LYS A 1 275 ? 184.859 216.209 152.153 1.00 23.11  ? 282 LYS A NZ  1 
ATOM   1720 N N   . ASN A 1 276 ? 179.328 218.434 148.735 1.00 21.25  ? 283 ASN A N   1 
ATOM   1721 C CA  . ASN A 1 276 ? 177.944 218.533 148.294 1.00 18.64  ? 283 ASN A CA  1 
ATOM   1722 C C   . ASN A 1 276 ? 177.068 218.994 149.432 1.00 16.76  ? 283 ASN A C   1 
ATOM   1723 O O   . ASN A 1 276 ? 177.341 218.712 150.600 1.00 16.79  ? 283 ASN A O   1 
ATOM   1724 C CB  . ASN A 1 276 ? 177.427 217.211 147.778 1.00 19.64  ? 283 ASN A CB  1 
ATOM   1725 C CG  . ASN A 1 276 ? 178.145 216.736 146.594 1.00 22.36  ? 283 ASN A CG  1 
ATOM   1726 O OD1 . ASN A 1 276 ? 178.658 217.508 145.786 1.00 23.49  ? 283 ASN A OD1 1 
ATOM   1727 N ND2 . ASN A 1 276 ? 178.201 215.445 146.439 1.00 26.69  ? 283 ASN A ND2 1 
ATOM   1728 N N   . ILE A 1 277 ? 175.980 219.636 149.077 1.00 14.90  ? 284 ILE A N   1 
ATOM   1729 C CA  . ILE A 1 277 ? 174.987 220.102 150.009 1.00 12.82  ? 284 ILE A CA  1 
ATOM   1730 C C   . ILE A 1 277 ? 173.716 219.288 149.868 1.00 12.89  ? 284 ILE A C   1 
ATOM   1731 O O   . ILE A 1 277 ? 173.116 219.224 148.793 1.00 13.89  ? 284 ILE A O   1 
ATOM   1732 C CB  . ILE A 1 277 ? 174.664 221.573 149.713 1.00 12.40  ? 284 ILE A CB  1 
ATOM   1733 C CG1 . ILE A 1 277 ? 175.926 222.427 149.830 1.00 13.57  ? 284 ILE A CG1 1 
ATOM   1734 C CG2 . ILE A 1 277 ? 173.625 222.035 150.650 1.00 11.54  ? 284 ILE A CG2 1 
ATOM   1735 C CD1 . ILE A 1 277 ? 175.782 223.839 149.293 1.00 13.51  ? 284 ILE A CD1 1 
ATOM   1736 N N   . LEU A 1 278 ? 173.284 218.671 150.948 1.00 12.74  ? 285 LEU A N   1 
ATOM   1737 C CA  . LEU A 1 278 ? 172.075 217.876 150.903 1.00 11.33  ? 285 LEU A CA  1 
ATOM   1738 C C   . LEU A 1 278 ? 170.958 218.698 151.505 1.00 10.60  ? 285 LEU A C   1 
ATOM   1739 O O   . LEU A 1 278 ? 171.026 219.099 152.664 1.00 12.52  ? 285 LEU A O   1 
ATOM   1740 C CB  . LEU A 1 278 ? 172.252 216.565 151.681 1.00 12.90  ? 285 LEU A CB  1 
ATOM   1741 C CG  . LEU A 1 278 ? 173.481 215.694 151.304 1.00 14.92  ? 285 LEU A CG  1 
ATOM   1742 C CD1 . LEU A 1 278 ? 173.489 214.423 152.174 1.00 14.83  ? 285 LEU A CD1 1 
ATOM   1743 C CD2 . LEU A 1 278 ? 173.464 215.350 149.845 1.00 15.87  ? 285 LEU A CD2 1 
ATOM   1744 N N   . VAL A 1 279 ? 169.939 218.990 150.725 1.00 10.71  ? 286 VAL A N   1 
ATOM   1745 C CA  . VAL A 1 279 ? 168.865 219.826 151.221 1.00 9.23   ? 286 VAL A CA  1 
ATOM   1746 C C   . VAL A 1 279 ? 167.621 219.000 151.434 1.00 9.54   ? 286 VAL A C   1 
ATOM   1747 O O   . VAL A 1 279 ? 167.075 218.469 150.477 1.00 12.01  ? 286 VAL A O   1 
ATOM   1748 C CB  . VAL A 1 279 ? 168.552 220.927 150.196 1.00 8.62   ? 286 VAL A CB  1 
ATOM   1749 C CG1 . VAL A 1 279 ? 167.447 221.798 150.687 1.00 9.50   ? 286 VAL A CG1 1 
ATOM   1750 C CG2 . VAL A 1 279 ? 169.804 221.726 149.895 1.00 9.67   ? 286 VAL A CG2 1 
ATOM   1751 N N   . GLN A 1 280 ? 167.155 218.904 152.669 1.00 10.83  ? 287 GLN A N   1 
ATOM   1752 C CA  . GLN A 1 280 ? 165.954 218.133 152.978 1.00 9.78   ? 287 GLN A CA  1 
ATOM   1753 C C   . GLN A 1 280 ? 164.773 219.068 152.989 1.00 10.42  ? 287 GLN A C   1 
ATOM   1754 O O   . GLN A 1 280 ? 164.796 220.089 153.669 1.00 13.14  ? 287 GLN A O   1 
ATOM   1755 C CB  . GLN A 1 280 ? 166.082 217.430 154.316 1.00 11.77  ? 287 GLN A CB  1 
ATOM   1756 C CG  . GLN A 1 280 ? 164.906 216.551 154.659 1.00 12.42  ? 287 GLN A CG  1 
ATOM   1757 C CD  . GLN A 1 280 ? 165.088 215.843 155.948 1.00 12.50  ? 287 GLN A CD  1 
ATOM   1758 O OE1 . GLN A 1 280 ? 165.737 216.372 156.866 1.00 13.83  ? 287 GLN A OE1 1 
ATOM   1759 N NE2 . GLN A 1 280 ? 164.529 214.660 156.036 1.00 13.75  ? 287 GLN A NE2 1 
ATOM   1760 N N   . LEU A 1 281 ? 163.725 218.733 152.269 1.00 11.32  ? 288 LEU A N   1 
ATOM   1761 C CA  . LEU A 1 281 ? 162.593 219.634 152.213 1.00 11.36  ? 288 LEU A CA  1 
ATOM   1762 C C   . LEU A 1 281 ? 161.631 219.292 153.318 1.00 13.98  ? 288 LEU A C   1 
ATOM   1763 O O   . LEU A 1 281 ? 161.632 218.157 153.778 1.00 17.28  ? 288 LEU A O   1 
ATOM   1764 C CB  . LEU A 1 281 ? 161.895 219.533 150.863 1.00 12.39  ? 288 LEU A CB  1 
ATOM   1765 C CG  . LEU A 1 281 ? 162.751 219.797 149.611 1.00 9.68   ? 288 LEU A CG  1 
ATOM   1766 C CD1 . LEU A 1 281 ? 161.868 219.613 148.396 1.00 10.37  ? 288 LEU A CD1 1 
ATOM   1767 C CD2 . LEU A 1 281 ? 163.415 221.165 149.658 1.00 10.42  ? 288 LEU A CD2 1 
ATOM   1768 N N   . ASN A 1 282 ? 160.814 220.254 153.764 1.00 16.78  ? 289 ASN A N   1 
ATOM   1769 C CA  . ASN A 1 282 ? 159.793 219.974 154.771 1.00 17.08  ? 289 ASN A CA  1 
ATOM   1770 C C   . ASN A 1 282 ? 158.415 219.747 154.154 1.00 19.13  ? 289 ASN A C   1 
ATOM   1771 O O   . ASN A 1 282 ? 157.440 219.472 154.852 1.00 20.50  ? 289 ASN A O   1 
ATOM   1772 C CB  . ASN A 1 282 ? 159.758 221.106 155.775 1.00 20.28  ? 289 ASN A CB  1 
ATOM   1773 C CG  . ASN A 1 282 ? 159.386 222.402 155.147 1.00 20.82  ? 289 ASN A CG  1 
ATOM   1774 O OD1 . ASN A 1 282 ? 159.439 222.533 153.902 1.00 20.54  ? 289 ASN A OD1 1 
ATOM   1775 N ND2 . ASN A 1 282 ? 159.028 223.378 155.943 1.00 22.21  ? 289 ASN A ND2 1 
ATOM   1776 N N   . THR A 1 283 ? 158.351 219.854 152.836 1.00 20.96  ? 290 THR A N   1 
ATOM   1777 C CA  . THR A 1 283 ? 157.151 219.623 152.052 1.00 20.03  ? 290 THR A CA  1 
ATOM   1778 C C   . THR A 1 283 ? 157.591 218.899 150.800 1.00 18.75  ? 290 THR A C   1 
ATOM   1779 O O   . THR A 1 283 ? 158.644 219.241 150.273 1.00 18.95  ? 290 THR A O   1 
ATOM   1780 C CB  . THR A 1 283 ? 156.465 220.941 151.647 1.00 22.62  ? 290 THR A CB  1 
ATOM   1781 O OG1 . THR A 1 283 ? 157.385 221.741 150.860 1.00 22.82  ? 290 THR A OG1 1 
ATOM   1782 C CG2 . THR A 1 283 ? 156.020 221.716 152.873 1.00 24.20  ? 290 THR A CG2 1 
ATOM   1783 N N   . PRO A 1 284 ? 156.812 217.971 150.250 1.00 18.97  ? 291 PRO A N   1 
ATOM   1784 C CA  . PRO A 1 284 ? 157.114 217.296 149.022 1.00 15.59  ? 291 PRO A CA  1 
ATOM   1785 C C   . PRO A 1 284 ? 156.785 218.190 147.855 1.00 15.92  ? 291 PRO A C   1 
ATOM   1786 O O   . PRO A 1 284 ? 155.823 218.954 147.938 1.00 17.97  ? 291 PRO A O   1 
ATOM   1787 C CB  . PRO A 1 284 ? 156.179 216.109 149.085 1.00 16.56  ? 291 PRO A CB  1 
ATOM   1788 C CG  . PRO A 1 284 ? 154.979 216.625 149.834 1.00 20.16  ? 291 PRO A CG  1 
ATOM   1789 C CD  . PRO A 1 284 ? 155.512 217.625 150.824 1.00 19.86  ? 291 PRO A CD  1 
ATOM   1790 N N   . VAL A 1 285 ? 157.461 218.000 146.741 1.00 13.46  ? 292 VAL A N   1 
ATOM   1791 C CA  . VAL A 1 285 ? 157.030 218.635 145.504 1.00 12.11  ? 292 VAL A CA  1 
ATOM   1792 C C   . VAL A 1 285 ? 156.645 217.502 144.574 1.00 12.24  ? 292 VAL A C   1 
ATOM   1793 O O   . VAL A 1 285 ? 157.422 216.586 144.346 1.00 13.83  ? 292 VAL A O   1 
ATOM   1794 C CB  . VAL A 1 285 ? 158.124 219.506 144.873 1.00 10.70  ? 292 VAL A CB  1 
ATOM   1795 C CG1 . VAL A 1 285 ? 157.619 220.142 143.598 1.00 12.03  ? 292 VAL A CG1 1 
ATOM   1796 C CG2 . VAL A 1 285 ? 158.591 220.506 145.852 1.00 12.38  ? 292 VAL A CG2 1 
ATOM   1797 N N   . GLN A 1 286 ? 155.426 217.492 144.086 1.00 15.15  ? 293 GLN A N   1 
ATOM   1798 C CA  . GLN A 1 286 ? 155.039 216.356 143.270 1.00 15.09  ? 293 GLN A CA  1 
ATOM   1799 C C   . GLN A 1 286 ? 155.504 216.517 141.842 1.00 15.08  ? 293 GLN A C   1 
ATOM   1800 O O   . GLN A 1 286 ? 155.313 217.576 141.242 1.00 16.70  ? 293 GLN A O   1 
ATOM   1801 C CB  . GLN A 1 286 ? 153.534 216.166 143.326 1.00 19.55  ? 293 GLN A CB  1 
ATOM   1802 C CG  . GLN A 1 286 ? 153.043 214.924 142.664 1.00 18.63  ? 293 GLN A CG  1 
ATOM   1803 C CD  . GLN A 1 286 ? 151.592 214.772 142.860 1.00 22.34  ? 293 GLN A CD  1 
ATOM   1804 O OE1 . GLN A 1 286 ? 150.810 215.590 142.383 1.00 25.24  ? 293 GLN A OE1 1 
ATOM   1805 N NE2 . GLN A 1 286 ? 151.186 213.750 143.592 1.00 25.89  ? 293 GLN A NE2 1 
ATOM   1806 N N   . ILE A 1 287 ? 156.114 215.460 141.314 1.00 16.88  ? 294 ILE A N   1 
ATOM   1807 C CA  . ILE A 1 287 ? 156.591 215.412 139.938 1.00 15.77  ? 294 ILE A CA  1 
ATOM   1808 C C   . ILE A 1 287 ? 155.933 214.219 139.182 1.00 15.29  ? 294 ILE A C   1 
ATOM   1809 O O   . ILE A 1 287 ? 155.995 213.072 139.642 1.00 17.76  ? 294 ILE A O   1 
ATOM   1810 C CB  . ILE A 1 287 ? 158.151 215.371 139.940 1.00 13.20  ? 294 ILE A CB  1 
ATOM   1811 C CG1 . ILE A 1 287 ? 158.704 215.369 138.518 1.00 13.14  ? 294 ILE A CG1 1 
ATOM   1812 C CG2 . ILE A 1 287 ? 158.673 214.199 140.748 1.00 12.38  ? 294 ILE A CG2 1 
ATOM   1813 C CD1 . ILE A 1 287 ? 160.210 215.679 138.411 1.00 8.40   ? 294 ILE A CD1 1 
ATOM   1814 N N   . ASN A 1 288 ? 155.307 214.511 138.016 1.00 17.21  ? 295 ASN A N   1 
ATOM   1815 C CA  . ASN A 1 288 ? 154.585 213.569 137.146 1.00 16.48  ? 295 ASN A CA  1 
ATOM   1816 C C   . ASN A 1 288 ? 155.379 213.267 135.875 1.00 16.71  ? 295 ASN A C   1 
ATOM   1817 O O   . ASN A 1 288 ? 155.576 214.157 135.046 1.00 17.24  ? 295 ASN A O   1 
ATOM   1818 C CB  . ASN A 1 288 ? 153.195 214.110 136.786 1.00 20.62  ? 295 ASN A CB  1 
ATOM   1819 C CG  . ASN A 1 288 ? 152.246 214.284 137.984 1.00 23.30  ? 295 ASN A CG  1 
ATOM   1820 O OD1 . ASN A 1 288 ? 152.555 213.894 139.121 1.00 23.33  ? 295 ASN A OD1 1 
ATOM   1821 N ND2 . ASN A 1 288 ? 151.091 214.873 137.715 1.00 28.41  ? 295 ASN A ND2 1 
ATOM   1822 N N   . CYS A 1 289 ? 155.877 212.022 135.710 1.00 17.56  ? 296 CYS A N   1 
ATOM   1823 C CA  . CYS A 1 289 ? 156.731 211.635 134.583 1.00 15.36  ? 296 CYS A CA  1 
ATOM   1824 C C   . CYS A 1 289 ? 156.016 210.668 133.654 1.00 15.13  ? 296 CYS A C   1 
ATOM   1825 O O   . CYS A 1 289 ? 155.289 209.764 134.077 1.00 18.51  ? 296 CYS A O   1 
ATOM   1826 C CB  . CYS A 1 289 ? 158.055 211.038 135.086 1.00 14.07  ? 296 CYS A CB  1 
ATOM   1827 S SG  . CYS A 1 289 ? 159.065 212.202 136.057 1.00 17.92  ? 296 CYS A SG  1 
ATOM   1828 N N   . THR A 1 290 ? 156.226 210.866 132.363 1.00 16.43  ? 297 THR A N   1 
ATOM   1829 C CA  . THR A 1 290 ? 155.614 210.004 131.379 1.00 15.94  ? 297 THR A CA  1 
ATOM   1830 C C   . THR A 1 290 ? 156.426 209.765 130.128 1.00 17.22  ? 297 THR A C   1 
ATOM   1831 O O   . THR A 1 290 ? 157.225 210.599 129.685 1.00 18.82  ? 297 THR A O   1 
ATOM   1832 C CB  . THR A 1 290 ? 154.254 210.559 130.944 1.00 17.53  ? 297 THR A CB  1 
ATOM   1833 O OG1 . THR A 1 290 ? 153.622 209.614 130.103 1.00 19.29  ? 297 THR A OG1 1 
ATOM   1834 C CG2 . THR A 1 290 ? 154.425 211.857 130.177 1.00 19.17  ? 297 THR A CG2 1 
ATOM   1835 N N   . ARG A 1 291 ? 156.166 208.615 129.530 1.00 18.27  ? 298 ARG A N   1 
ATOM   1836 C CA  . ARG A 1 291 ? 156.677 208.225 128.238 1.00 17.45  ? 298 ARG A CA  1 
ATOM   1837 C C   . ARG A 1 291 ? 155.448 207.979 127.370 1.00 17.91  ? 298 ARG A C   1 
ATOM   1838 O O   . ARG A 1 291 ? 154.974 206.840 127.286 1.00 21.06  ? 298 ARG A O   1 
ATOM   1839 C CB  . ARG A 1 291 ? 157.475 206.956 128.281 1.00 17.65  ? 298 ARG A CB  1 
ATOM   1840 C CG  . ARG A 1 291 ? 158.112 206.625 126.947 1.00 17.56  ? 298 ARG A CG  1 
ATOM   1841 C CD  . ARG A 1 291 ? 158.661 205.316 126.948 1.00 18.71  ? 298 ARG A CD  1 
ATOM   1842 N NE  . ARG A 1 291 ? 157.585 204.320 126.991 1.00 19.22  ? 298 ARG A NE  1 
ATOM   1843 C CZ  . ARG A 1 291 ? 157.781 203.019 127.186 1.00 20.64  ? 298 ARG A CZ  1 
ATOM   1844 N NH1 . ARG A 1 291 ? 159.000 202.612 127.338 1.00 23.58  ? 298 ARG A NH1 1 
ATOM   1845 N NH2 . ARG A 1 291 ? 156.770 202.149 127.226 1.00 19.57  ? 298 ARG A NH2 1 
ATOM   1846 N N   . PRO A 1 292 ? 154.930 209.007 126.678 1.00 18.50  ? 299 PRO A N   1 
ATOM   1847 C CA  . PRO A 1 292 ? 153.647 209.047 126.002 1.00 20.77  ? 299 PRO A CA  1 
ATOM   1848 C C   . PRO A 1 292 ? 153.650 208.389 124.637 1.00 25.18  ? 299 PRO A C   1 
ATOM   1849 O O   . PRO A 1 292 ? 153.214 208.987 123.650 1.00 29.66  ? 299 PRO A O   1 
ATOM   1850 C CB  . PRO A 1 292 ? 153.466 210.551 125.847 1.00 23.21  ? 299 PRO A CB  1 
ATOM   1851 C CG  . PRO A 1 292 ? 154.865 211.053 125.621 1.00 22.15  ? 299 PRO A CG  1 
ATOM   1852 C CD  . PRO A 1 292 ? 155.722 210.219 126.492 1.00 20.33  ? 299 PRO A CD  1 
ATOM   1853 N N   . ASN A 1 293 ? 154.105 207.157 124.579 1.00 25.72  ? 300 ASN A N   1 
ATOM   1854 C CA  . ASN A 1 293 ? 154.210 206.411 123.339 1.00 24.32  ? 300 ASN A CA  1 
ATOM   1855 C C   . ASN A 1 293 ? 153.756 205.021 123.662 1.00 24.32  ? 300 ASN A C   1 
ATOM   1856 O O   . ASN A 1 293 ? 154.120 204.531 124.729 1.00 23.73  ? 300 ASN A O   1 
ATOM   1857 C CB  . ASN A 1 293 ? 155.636 206.377 122.813 1.00 23.43  ? 300 ASN A CB  1 
ATOM   1858 C CG  . ASN A 1 293 ? 156.163 207.715 122.439 1.00 25.96  ? 300 ASN A CG  1 
ATOM   1859 O OD1 . ASN A 1 293 ? 155.690 208.350 121.501 1.00 29.05  ? 300 ASN A OD1 1 
ATOM   1860 N ND2 . ASN A 1 293 ? 157.154 208.161 123.143 1.00 25.46  ? 300 ASN A ND2 1 
ATOM   1861 N N   . ASN A 1 294 ? 152.947 204.407 122.780 1.00 25.94  ? 301 ASN A N   1 
ATOM   1862 C CA  . ASN A 1 294 ? 152.430 203.052 122.936 1.00 25.13  ? 301 ASN A CA  1 
ATOM   1863 C C   . ASN A 1 294 ? 153.368 202.058 122.238 1.00 25.23  ? 301 ASN A C   1 
ATOM   1864 O O   . ASN A 1 294 ? 153.406 201.979 121.003 1.00 27.61  ? 301 ASN A O   1 
ATOM   1865 C CB  . ASN A 1 294 ? 150.983 202.965 122.420 1.00 29.16  ? 301 ASN A CB  1 
ATOM   1866 C CG  . ASN A 1 294 ? 150.184 201.721 122.919 1.00 32.66  ? 301 ASN A CG  1 
ATOM   1867 O OD1 . ASN A 1 294 ? 150.711 200.881 123.665 1.00 30.94  ? 301 ASN A OD1 1 
ATOM   1868 N ND2 . ASN A 1 294 ? 148.919 201.629 122.514 1.00 38.07  ? 301 ASN A ND2 1 
ATOM   1869 N N   . ASN A 1 295 ? 154.188 201.353 123.046 1.00 25.49  ? 302 ASN A N   1 
ATOM   1870 C CA  . ASN A 1 295 ? 155.224 200.416 122.600 1.00 21.43  ? 302 ASN A CA  1 
ATOM   1871 C C   . ASN A 1 295 ? 154.744 198.989 122.491 1.00 22.78  ? 302 ASN A C   1 
ATOM   1872 O O   . ASN A 1 295 ? 154.195 198.414 123.435 1.00 25.14  ? 302 ASN A O   1 
ATOM   1873 C CB  . ASN A 1 295 ? 156.418 200.521 123.509 1.00 21.19  ? 302 ASN A CB  1 
ATOM   1874 C CG  . ASN A 1 295 ? 157.120 201.806 123.287 1.00 22.83  ? 302 ASN A CG  1 
ATOM   1875 O OD1 . ASN A 1 295 ? 157.963 201.942 122.400 1.00 22.97  ? 302 ASN A OD1 1 
ATOM   1876 N ND2 . ASN A 1 295 ? 156.754 202.784 124.038 1.00 28.02  ? 302 ASN A ND2 1 
ATOM   1877 N N   . THR A 1 296 ? 154.970 198.414 121.317 1.00 25.45  ? 303 THR A N   1 
ATOM   1878 C CA  . THR A 1 296 ? 154.638 197.033 121.030 1.00 23.20  ? 303 THR A CA  1 
ATOM   1879 C C   . THR A 1 296 ? 155.897 196.250 121.256 1.00 20.45  ? 303 THR A C   1 
ATOM   1880 O O   . THR A 1 296 ? 156.866 196.412 120.499 1.00 21.03  ? 303 THR A O   1 
ATOM   1881 C CB  . THR A 1 296 ? 154.245 196.850 119.555 1.00 25.37  ? 303 THR A CB  1 
ATOM   1882 O OG1 . THR A 1 296 ? 153.115 197.639 119.242 1.00 27.63  ? 303 THR A OG1 1 
ATOM   1883 C CG2 . THR A 1 296 ? 153.937 195.402 119.257 1.00 26.10  ? 303 THR A CG2 1 
ATOM   1884 N N   . VAL A 1 297 ? 155.859 195.356 122.226 1.00 19.87  ? 304 VAL A N   1 
ATOM   1885 C CA  . VAL A 1 297 ? 157.016 194.576 122.611 1.00 18.22  ? 304 VAL A CA  1 
ATOM   1886 C C   . VAL A 1 297 ? 156.944 193.160 122.079 1.00 19.41  ? 304 VAL A C   1 
ATOM   1887 O O   . VAL A 1 297 ? 155.948 192.456 122.239 1.00 21.51  ? 304 VAL A O   1 
ATOM   1888 C CB  . VAL A 1 297 ? 157.198 194.632 124.132 1.00 17.27  ? 304 VAL A CB  1 
ATOM   1889 C CG1 . VAL A 1 297 ? 158.363 193.762 124.583 1.00 16.57  ? 304 VAL A CG1 1 
ATOM   1890 C CG2 . VAL A 1 297 ? 157.464 196.089 124.509 1.00 18.21  ? 304 VAL A CG2 1 
ATOM   1891 N N   . LYS A 1 298 ? 158.012 192.779 121.400 1.00 17.00  ? 305 LYS A N   1 
ATOM   1892 C CA  . LYS A 1 298 ? 158.165 191.509 120.731 1.00 15.65  ? 305 LYS A CA  1 
ATOM   1893 C C   . LYS A 1 298 ? 159.354 190.760 121.287 1.00 14.21  ? 305 LYS A C   1 
ATOM   1894 O O   . LYS A 1 298 ? 160.231 191.354 121.914 1.00 16.64  ? 305 LYS A O   1 
ATOM   1895 C CB  . LYS A 1 298 ? 158.306 191.746 119.235 1.00 15.62  ? 305 LYS A CB  1 
ATOM   1896 C CG  . LYS A 1 298 ? 157.078 192.378 118.636 1.00 19.14  ? 305 LYS A CG  1 
ATOM   1897 C CD  . LYS A 1 298 ? 157.157 192.557 117.134 1.00 21.71  ? 305 LYS A CD  1 
ATOM   1898 C CE  . LYS A 1 298 ? 155.874 193.236 116.637 1.00 31.31  ? 305 LYS A CE  1 
ATOM   1899 N NZ  . LYS A 1 298 ? 155.862 193.492 115.171 1.00 36.06  ? 305 LYS A NZ  1 
ATOM   1900 N N   . SER A 1 299 ? 159.415 189.458 121.059 1.00 16.74  ? 306 SER A N   1 
ATOM   1901 C CA  . SER A 1 299 ? 160.586 188.729 121.503 1.00 14.68  ? 306 SER A CA  1 
ATOM   1902 C C   . SER A 1 299 ? 160.978 187.636 120.543 1.00 16.72  ? 306 SER A C   1 
ATOM   1903 O O   . SER A 1 299 ? 160.175 187.165 119.732 1.00 18.47  ? 306 SER A O   1 
ATOM   1904 C CB  . SER A 1 299 ? 160.349 188.105 122.851 1.00 14.73  ? 306 SER A CB  1 
ATOM   1905 O OG  . SER A 1 299 ? 159.367 187.122 122.775 1.00 18.05  ? 306 SER A OG  1 
ATOM   1906 N N   . ILE A 1 300 ? 162.246 187.269 120.624 1.00 16.64  ? 307 ILE A N   1 
ATOM   1907 C CA  . ILE A 1 300 ? 162.820 186.180 119.851 1.00 14.68  ? 307 ILE A CA  1 
ATOM   1908 C C   . ILE A 1 300 ? 163.635 185.249 120.706 1.00 14.78  ? 307 ILE A C   1 
ATOM   1909 O O   . ILE A 1 300 ? 164.183 185.648 121.730 1.00 15.89  ? 307 ILE A O   1 
ATOM   1910 C CB  . ILE A 1 300 ? 163.706 186.718 118.718 1.00 14.37  ? 307 ILE A CB  1 
ATOM   1911 C CG1 . ILE A 1 300 ? 164.827 187.566 119.334 1.00 14.41  ? 307 ILE A CG1 1 
ATOM   1912 C CG2 . ILE A 1 300 ? 162.884 187.431 117.687 1.00 15.42  ? 307 ILE A CG2 1 
ATOM   1913 C CD1 . ILE A 1 300 ? 165.860 188.020 118.401 1.00 13.02  ? 307 ILE A CD1 1 
ATOM   1914 N N   . ARG A 1 301 ? 163.802 184.024 120.249 1.00 18.16  ? 308 ARG A N   1 
ATOM   1915 C CA  . ARG A 1 301 ? 164.693 183.131 120.953 1.00 17.12  ? 308 ARG A CA  1 
ATOM   1916 C C   . ARG A 1 301 ? 166.034 183.247 120.299 1.00 17.69  ? 308 ARG A C   1 
ATOM   1917 O O   . ARG A 1 301 ? 166.143 183.127 119.083 1.00 19.64  ? 308 ARG A O   1 
ATOM   1918 C CB  . ARG A 1 301 ? 164.216 181.697 120.925 1.00 19.60  ? 308 ARG A CB  1 
ATOM   1919 C CG  . ARG A 1 301 ? 162.882 181.438 121.598 1.00 23.08  ? 308 ARG A CG  1 
ATOM   1920 C CD  . ARG A 1 301 ? 162.992 181.443 123.086 1.00 23.61  ? 308 ARG A CD  1 
ATOM   1921 N NE  . ARG A 1 301 ? 161.736 181.045 123.715 1.00 30.65  ? 308 ARG A NE  1 
ATOM   1922 C CZ  . ARG A 1 301 ? 161.520 180.949 125.045 1.00 32.56  ? 308 ARG A CZ  1 
ATOM   1923 N NH1 . ARG A 1 301 ? 162.474 181.225 125.898 1.00 29.37  ? 308 ARG A NH1 1 
ATOM   1924 N NH2 . ARG A 1 301 ? 160.338 180.568 125.497 1.00 38.83  ? 308 ARG A NH2 1 
ATOM   1925 N N   . ILE A 1 302 ? 167.046 183.495 121.110 1.00 17.57  ? 309 ILE A N   1 
ATOM   1926 C CA  . ILE A 1 302 ? 168.410 183.644 120.642 1.00 16.96  ? 309 ILE A CA  1 
ATOM   1927 C C   . ILE A 1 302 ? 169.243 182.471 121.102 1.00 17.21  ? 309 ILE A C   1 
ATOM   1928 O O   . ILE A 1 302 ? 170.382 182.284 120.675 1.00 19.15  ? 309 ILE A O   1 
ATOM   1929 C CB  . ILE A 1 302 ? 169.006 185.018 121.050 1.00 16.79  ? 309 ILE A CB  1 
ATOM   1930 C CG1 . ILE A 1 302 ? 169.066 185.193 122.595 1.00 16.80  ? 309 ILE A CG1 1 
ATOM   1931 C CG2 . ILE A 1 302 ? 168.186 186.100 120.411 1.00 14.97  ? 309 ILE A CG2 1 
ATOM   1932 C CD1 . ILE A 1 302 ? 169.851 186.424 123.066 1.00 16.47  ? 309 ILE A CD1 1 
ATOM   1933 N N   . GLY A 1 303 ? 168.636 181.632 121.919 1.00 19.11  ? 312 GLY A N   1 
ATOM   1934 C CA  . GLY A 1 303 ? 169.322 180.450 122.388 1.00 19.78  ? 312 GLY A CA  1 
ATOM   1935 C C   . GLY A 1 303 ? 168.357 179.463 123.028 1.00 20.43  ? 312 GLY A C   1 
ATOM   1936 O O   . GLY A 1 303 ? 167.141 179.679 123.038 1.00 22.14  ? 312 GLY A O   1 
ATOM   1937 N N   . PRO A 1 304 ? 168.861 178.418 123.670 1.00 21.46  ? 313 PRO A N   1 
ATOM   1938 C CA  . PRO A 1 304 ? 168.110 177.321 124.244 1.00 20.65  ? 313 PRO A CA  1 
ATOM   1939 C C   . PRO A 1 304 ? 167.323 177.749 125.462 1.00 19.91  ? 313 PRO A C   1 
ATOM   1940 O O   . PRO A 1 304 ? 167.803 177.691 126.595 1.00 21.57  ? 313 PRO A O   1 
ATOM   1941 C CB  . PRO A 1 304 ? 169.204 176.316 124.570 1.00 22.39  ? 313 PRO A CB  1 
ATOM   1942 C CG  . PRO A 1 304 ? 170.411 177.156 124.854 1.00 25.01  ? 313 PRO A CG  1 
ATOM   1943 C CD  . PRO A 1 304 ? 170.307 178.328 123.898 1.00 25.53  ? 313 PRO A CD  1 
ATOM   1944 N N   . GLY A 1 305 ? 166.144 178.301 125.194 1.00 21.45  ? 314 GLY A N   1 
ATOM   1945 C CA  . GLY A 1 305 ? 165.262 178.813 126.227 1.00 23.18  ? 314 GLY A CA  1 
ATOM   1946 C C   . GLY A 1 305 ? 165.583 180.248 126.590 1.00 24.26  ? 314 GLY A C   1 
ATOM   1947 O O   . GLY A 1 305 ? 165.118 180.761 127.608 1.00 25.84  ? 314 GLY A O   1 
ATOM   1948 N N   . GLN A 1 306 ? 166.370 180.901 125.748 1.00 24.25  ? 315 GLN A N   1 
ATOM   1949 C CA  . GLN A 1 306 ? 166.802 182.267 125.998 1.00 19.93  ? 315 GLN A CA  1 
ATOM   1950 C C   . GLN A 1 306 ? 166.113 183.283 125.117 1.00 18.70  ? 315 GLN A C   1 
ATOM   1951 O O   . GLN A 1 306 ? 166.351 183.341 123.904 1.00 20.71  ? 315 GLN A O   1 
ATOM   1952 C CB  . GLN A 1 306 ? 168.294 182.374 125.792 1.00 19.65  ? 315 GLN A CB  1 
ATOM   1953 C CG  . GLN A 1 306 ? 169.076 181.542 126.726 1.00 20.49  ? 315 GLN A CG  1 
ATOM   1954 C CD  . GLN A 1 306 ? 170.515 181.754 126.551 1.00 23.14  ? 315 GLN A CD  1 
ATOM   1955 O OE1 . GLN A 1 306 ? 171.028 181.778 125.432 1.00 24.23  ? 315 GLN A OE1 1 
ATOM   1956 N NE2 . GLN A 1 306 ? 171.214 181.934 127.661 1.00 26.15  ? 315 GLN A NE2 1 
ATOM   1957 N N   . ALA A 1 307 ? 165.244 184.094 125.725 1.00 18.66  ? 316 ALA A N   1 
ATOM   1958 C CA  . ALA A 1 307 ? 164.491 185.083 124.966 1.00 15.89  ? 316 ALA A CA  1 
ATOM   1959 C C   . ALA A 1 307 ? 165.003 186.497 125.167 1.00 14.67  ? 316 ALA A C   1 
ATOM   1960 O O   . ALA A 1 307 ? 165.214 186.946 126.295 1.00 15.46  ? 316 ALA A O   1 
ATOM   1961 C CB  . ALA A 1 307 ? 163.023 185.052 125.344 1.00 17.70  ? 316 ALA A CB  1 
ATOM   1962 N N   . PHE A 1 308 ? 165.077 187.205 124.058 1.00 13.27  ? 317 PHE A N   1 
ATOM   1963 C CA  . PHE A 1 308 ? 165.435 188.606 123.966 1.00 11.19  ? 317 PHE A CA  1 
ATOM   1964 C C   . PHE A 1 308 ? 164.207 189.444 123.718 1.00 12.52  ? 317 PHE A C   1 
ATOM   1965 O O   . PHE A 1 308 ? 163.398 189.136 122.840 1.00 14.04  ? 317 PHE A O   1 
ATOM   1966 C CB  . PHE A 1 308 ? 166.464 188.810 122.872 1.00 11.57  ? 317 PHE A CB  1 
ATOM   1967 C CG  . PHE A 1 308 ? 166.758 190.223 122.549 1.00 10.87  ? 317 PHE A CG  1 
ATOM   1968 C CD1 . PHE A 1 308 ? 167.341 191.064 123.445 1.00 9.67   ? 317 PHE A CD1 1 
ATOM   1969 C CD2 . PHE A 1 308 ? 166.466 190.703 121.303 1.00 10.21  ? 317 PHE A CD2 1 
ATOM   1970 C CE1 . PHE A 1 308 ? 167.606 192.347 123.112 1.00 8.41   ? 317 PHE A CE1 1 
ATOM   1971 C CE2 . PHE A 1 308 ? 166.734 191.980 120.965 1.00 8.69   ? 317 PHE A CE2 1 
ATOM   1972 C CZ  . PHE A 1 308 ? 167.304 192.808 121.875 1.00 7.62   ? 317 PHE A CZ  1 
ATOM   1973 N N   . TYR A 1 309 ? 164.047 190.506 124.498 1.00 12.94  ? 318 TYR A N   1 
ATOM   1974 C CA  . TYR A 1 309 ? 162.889 191.377 124.350 1.00 10.64  ? 318 TYR A CA  1 
ATOM   1975 C C   . TYR A 1 309 ? 163.252 192.699 123.735 1.00 9.73   ? 318 TYR A C   1 
ATOM   1976 O O   . TYR A 1 309 ? 164.219 193.336 124.134 1.00 11.31  ? 318 TYR A O   1 
ATOM   1977 C CB  . TYR A 1 309 ? 162.259 191.590 125.703 1.00 12.45  ? 318 TYR A CB  1 
ATOM   1978 C CG  . TYR A 1 309 ? 161.690 190.348 126.238 1.00 13.39  ? 318 TYR A CG  1 
ATOM   1979 C CD1 . TYR A 1 309 ? 162.488 189.486 126.929 1.00 14.65  ? 318 TYR A CD1 1 
ATOM   1980 C CD2 . TYR A 1 309 ? 160.382 190.055 126.033 1.00 14.80  ? 318 TYR A CD2 1 
ATOM   1981 C CE1 . TYR A 1 309 ? 161.985 188.326 127.408 1.00 15.21  ? 318 TYR A CE1 1 
ATOM   1982 C CE2 . TYR A 1 309 ? 159.870 188.892 126.518 1.00 15.64  ? 318 TYR A CE2 1 
ATOM   1983 C CZ  . TYR A 1 309 ? 160.670 188.028 127.203 1.00 15.79  ? 318 TYR A CZ  1 
ATOM   1984 O OH  . TYR A 1 309 ? 160.155 186.859 127.689 1.00 18.90  ? 318 TYR A OH  1 
ATOM   1985 N N   . TYR A 1 310 ? 162.425 193.159 122.823 1.00 10.74  ? 319 TYR A N   1 
ATOM   1986 C CA  . TYR A 1 310 ? 162.680 194.410 122.145 1.00 10.44  ? 319 TYR A CA  1 
ATOM   1987 C C   . TYR A 1 310 ? 161.426 195.129 121.700 1.00 12.37  ? 319 TYR A C   1 
ATOM   1988 O O   . TYR A 1 310 ? 160.355 194.536 121.600 1.00 15.87  ? 319 TYR A O   1 
ATOM   1989 C CB  . TYR A 1 310 ? 163.577 194.138 120.952 1.00 10.32  ? 319 TYR A CB  1 
ATOM   1990 C CG  . TYR A 1 310 ? 162.971 193.202 119.928 1.00 11.45  ? 319 TYR A CG  1 
ATOM   1991 C CD1 . TYR A 1 310 ? 163.137 191.860 120.063 1.00 11.76  ? 319 TYR A CD1 1 
ATOM   1992 C CD2 . TYR A 1 310 ? 162.263 193.683 118.871 1.00 13.07  ? 319 TYR A CD2 1 
ATOM   1993 C CE1 . TYR A 1 310 ? 162.602 191.028 119.163 1.00 12.07  ? 319 TYR A CE1 1 
ATOM   1994 C CE2 . TYR A 1 310 ? 161.729 192.848 117.963 1.00 12.64  ? 319 TYR A CE2 1 
ATOM   1995 C CZ  . TYR A 1 310 ? 161.891 191.517 118.106 1.00 13.32  ? 319 TYR A CZ  1 
ATOM   1996 O OH  . TYR A 1 310 ? 161.331 190.676 117.174 1.00 15.71  ? 319 TYR A OH  1 
ATOM   1997 N N   . THR A 1 311 ? 161.555 196.419 121.409 1.00 13.91  ? 320 THR A N   1 
ATOM   1998 C CA  . THR A 1 311 ? 160.413 197.144 120.897 1.00 14.29  ? 320 THR A CA  1 
ATOM   1999 C C   . THR A 1 311 ? 160.365 196.879 119.418 1.00 15.20  ? 320 THR A C   1 
ATOM   2000 O O   . THR A 1 311 ? 161.340 197.098 118.702 1.00 15.71  ? 320 THR A O   1 
ATOM   2001 C CB  . THR A 1 311 ? 160.517 198.668 121.141 1.00 15.50  ? 320 THR A CB  1 
ATOM   2002 O OG1 . THR A 1 311 ? 160.611 198.934 122.540 1.00 17.55  ? 320 THR A OG1 1 
ATOM   2003 C CG2 . THR A 1 311 ? 159.274 199.370 120.602 1.00 18.72  ? 320 THR A CG2 1 
ATOM   2004 N N   . GLY A 1 312 ? 159.233 196.395 118.966 1.00 17.55  ? 321 GLY A N   1 
ATOM   2005 C CA  . GLY A 1 312 ? 159.012 196.067 117.579 1.00 19.55  ? 321 GLY A CA  1 
ATOM   2006 C C   . GLY A 1 312 ? 158.594 197.316 116.862 1.00 23.30  ? 321 GLY A C   1 
ATOM   2007 O O   . GLY A 1 312 ? 159.117 197.682 115.809 1.00 23.98  ? 321 GLY A O   1 
ATOM   2008 N N   . ASP A 1 313 ? 157.603 197.966 117.433 1.00 24.15  ? 322 ASP A N   1 
ATOM   2009 C CA  . ASP A 1 313 ? 157.090 199.174 116.836 1.00 24.76  ? 322 ASP A CA  1 
ATOM   2010 C C   . ASP A 1 313 ? 156.388 200.079 117.828 1.00 24.04  ? 322 ASP A C   1 
ATOM   2011 O O   . ASP A 1 313 ? 156.158 199.706 118.982 1.00 24.42  ? 322 ASP A O   1 
ATOM   2012 C CB  . ASP A 1 313 ? 156.199 198.809 115.628 1.00 28.75  ? 322 ASP A CB  1 
ATOM   2013 C CG  . ASP A 1 313 ? 154.962 197.878 115.906 1.00 31.11  ? 322 ASP A CG  1 
ATOM   2014 O OD1 . ASP A 1 313 ? 154.062 198.255 116.631 1.00 30.08  ? 322 ASP A OD1 1 
ATOM   2015 O OD2 . ASP A 1 313 ? 154.952 196.775 115.379 1.00 32.22  ? 322 ASP A OD2 1 
ATOM   2016 N N   . ILE A 1 314 ? 156.030 201.266 117.350 1.00 26.68  ? 323 ILE A N   1 
ATOM   2017 C CA  . ILE A 1 314 ? 155.280 202.247 118.117 1.00 27.17  ? 323 ILE A CA  1 
ATOM   2018 C C   . ILE A 1 314 ? 153.984 202.520 117.398 1.00 27.30  ? 323 ILE A C   1 
ATOM   2019 O O   . ILE A 1 314 ? 153.971 202.695 116.177 1.00 29.54  ? 323 ILE A O   1 
ATOM   2020 C CB  . ILE A 1 314 ? 156.072 203.546 118.344 1.00 27.01  ? 323 ILE A CB  1 
ATOM   2021 C CG1 . ILE A 1 314 ? 157.335 203.206 119.140 1.00 25.04  ? 323 ILE A CG1 1 
ATOM   2022 C CG2 . ILE A 1 314 ? 155.186 204.594 119.099 1.00 29.45  ? 323 ILE A CG2 1 
ATOM   2023 C CD1 . ILE A 1 314 ? 158.346 204.303 119.228 1.00 24.93  ? 323 ILE A CD1 1 
ATOM   2024 N N   . ILE A 1 315 A 152.906 202.488 118.153 1.00 27.99  ? 323 ILE A N   1 
ATOM   2025 C CA  . ILE A 1 315 A 151.582 202.714 117.642 1.00 27.85  ? 323 ILE A CA  1 
ATOM   2026 C C   . ILE A 1 315 A 151.262 204.180 117.796 1.00 28.44  ? 323 ILE A C   1 
ATOM   2027 O O   . ILE A 1 315 A 151.235 204.711 118.905 1.00 30.68  ? 323 ILE A O   1 
ATOM   2028 C CB  . ILE A 1 315 A 150.573 201.879 118.439 1.00 28.30  ? 323 ILE A CB  1 
ATOM   2029 C CG1 . ILE A 1 315 A 150.915 200.387 118.310 1.00 28.31  ? 323 ILE A CG1 1 
ATOM   2030 C CG2 . ILE A 1 315 A 149.144 202.187 117.976 1.00 28.48  ? 323 ILE A CG2 1 
ATOM   2031 C CD1 . ILE A 1 315 A 150.191 199.501 119.307 1.00 32.47  ? 323 ILE A CD1 1 
ATOM   2032 N N   . GLY A 1 316 ? 150.979 204.831 116.692 1.00 31.37  ? 324 GLY A N   1 
ATOM   2033 C CA  . GLY A 1 316 ? 150.695 206.248 116.724 1.00 34.43  ? 324 GLY A CA  1 
ATOM   2034 C C   . GLY A 1 316 ? 151.959 207.077 116.633 1.00 34.20  ? 324 GLY A C   1 
ATOM   2035 O O   . GLY A 1 316 ? 153.023 206.578 116.267 1.00 34.23  ? 324 GLY A O   1 
ATOM   2036 N N   . ASP A 1 317 ? 151.803 208.364 116.924 1.00 38.54  ? 325 ASP A N   1 
ATOM   2037 C CA  . ASP A 1 317 ? 152.836 209.388 116.799 1.00 40.92  ? 325 ASP A CA  1 
ATOM   2038 C C   . ASP A 1 317 ? 153.938 209.190 117.816 1.00 36.69  ? 325 ASP A C   1 
ATOM   2039 O O   . ASP A 1 317 ? 153.712 208.601 118.872 1.00 35.68  ? 325 ASP A O   1 
ATOM   2040 C CB  . ASP A 1 317 ? 152.244 210.773 117.040 1.00 44.01  ? 325 ASP A CB  1 
ATOM   2041 C CG  . ASP A 1 317 ? 151.243 211.238 115.996 1.00 44.32  ? 325 ASP A CG  1 
ATOM   2042 O OD1 . ASP A 1 317 ? 151.115 210.642 114.956 1.00 51.11  ? 325 ASP A OD1 1 
ATOM   2043 O OD2 . ASP A 1 317 ? 150.582 212.205 116.277 1.00 54.84  ? 325 ASP A OD2 1 
ATOM   2044 N N   . ILE A 1 318 ? 155.124 209.701 117.503 1.00 37.58  ? 326 ILE A N   1 
ATOM   2045 C CA  . ILE A 1 318 ? 156.251 209.626 118.416 1.00 36.47  ? 326 ILE A CA  1 
ATOM   2046 C C   . ILE A 1 318 ? 156.565 210.972 119.063 1.00 34.76  ? 326 ILE A C   1 
ATOM   2047 O O   . ILE A 1 318 ? 156.903 211.963 118.399 1.00 33.63  ? 326 ILE A O   1 
ATOM   2048 C CB  . ILE A 1 318 ? 157.459 209.028 117.700 1.00 36.16  ? 326 ILE A CB  1 
ATOM   2049 C CG1 . ILE A 1 318 ? 157.095 207.597 117.266 1.00 32.91  ? 326 ILE A CG1 1 
ATOM   2050 C CG2 . ILE A 1 318 ? 158.699 209.077 118.573 1.00 36.15  ? 326 ILE A CG2 1 
ATOM   2051 C CD1 . ILE A 1 318 ? 158.051 206.940 116.345 1.00 33.41  ? 326 ILE A CD1 1 
ATOM   2052 N N   . ARG A 1 319 ? 156.476 210.978 120.391 1.00 35.65  ? 327 ARG A N   1 
ATOM   2053 C CA  . ARG A 1 319 ? 156.635 212.171 121.213 1.00 32.57  ? 327 ARG A CA  1 
ATOM   2054 C C   . ARG A 1 319 ? 157.697 212.003 122.293 1.00 29.51  ? 327 ARG A C   1 
ATOM   2055 O O   . ARG A 1 319 ? 158.052 210.890 122.684 1.00 28.88  ? 327 ARG A O   1 
ATOM   2056 C CB  . ARG A 1 319 ? 155.306 212.526 121.834 1.00 30.74  ? 327 ARG A CB  1 
ATOM   2057 C CG  . ARG A 1 319 ? 154.248 212.900 120.817 1.00 34.86  ? 327 ARG A CG  1 
ATOM   2058 C CD  . ARG A 1 319 ? 152.958 213.222 121.433 1.00 38.55  ? 327 ARG A CD  1 
ATOM   2059 N NE  . ARG A 1 319 ? 152.385 212.057 122.082 1.00 36.68  ? 327 ARG A NE  1 
ATOM   2060 C CZ  . ARG A 1 319 ? 151.181 211.996 122.665 1.00 39.59  ? 327 ARG A CZ  1 
ATOM   2061 N NH1 . ARG A 1 319 ? 150.372 213.043 122.678 1.00 45.83  ? 327 ARG A NH1 1 
ATOM   2062 N NH2 . ARG A 1 319 ? 150.823 210.860 123.224 1.00 36.99  ? 327 ARG A NH2 1 
ATOM   2063 N N   . GLN A 1 320 ? 158.230 213.116 122.772 1.00 27.45  ? 328 GLN A N   1 
ATOM   2064 C CA  . GLN A 1 320 ? 159.268 213.056 123.781 1.00 25.69  ? 328 GLN A CA  1 
ATOM   2065 C C   . GLN A 1 320 ? 158.732 212.823 125.184 1.00 23.30  ? 328 GLN A C   1 
ATOM   2066 O O   . GLN A 1 320 ? 157.699 213.384 125.562 1.00 24.47  ? 328 GLN A O   1 
ATOM   2067 C CB  . GLN A 1 320 ? 160.123 214.319 123.714 1.00 27.72  ? 328 GLN A CB  1 
ATOM   2068 C CG  . GLN A 1 320 ? 161.359 214.256 124.559 1.00 24.78  ? 328 GLN A CG  1 
ATOM   2069 C CD  . GLN A 1 320 ? 162.247 215.396 124.359 1.00 27.49  ? 328 GLN A CD  1 
ATOM   2070 O OE1 . GLN A 1 320 ? 161.802 216.538 124.269 1.00 29.44  ? 328 GLN A OE1 1 
ATOM   2071 N NE2 . GLN A 1 320 ? 163.537 215.118 124.281 1.00 26.50  ? 328 GLN A NE2 1 
ATOM   2072 N N   . ALA A 1 321 ? 159.449 211.979 125.934 1.00 21.68  ? 329 ALA A N   1 
ATOM   2073 C CA  . ALA A 1 321 ? 159.164 211.702 127.335 1.00 17.28  ? 329 ALA A CA  1 
ATOM   2074 C C   . ALA A 1 321 ? 159.445 212.957 128.126 1.00 17.77  ? 329 ALA A C   1 
ATOM   2075 O O   . ALA A 1 321 ? 160.288 213.764 127.732 1.00 18.79  ? 329 ALA A O   1 
ATOM   2076 C CB  . ALA A 1 321 ? 159.993 210.539 127.839 1.00 15.13  ? 329 ALA A CB  1 
ATOM   2077 N N   . HIS A 1 322 ? 158.706 213.169 129.188 1.00 18.22  ? 330 HIS A N   1 
ATOM   2078 C CA  . HIS A 1 322 ? 158.903 214.374 129.977 1.00 16.30  ? 330 HIS A CA  1 
ATOM   2079 C C   . HIS A 1 322 ? 158.364 214.250 131.402 1.00 16.21  ? 330 HIS A C   1 
ATOM   2080 O O   . HIS A 1 322 ? 157.559 213.351 131.666 1.00 18.00  ? 330 HIS A O   1 
ATOM   2081 C CB  . HIS A 1 322 ? 158.238 215.550 129.258 1.00 18.63  ? 330 HIS A CB  1 
ATOM   2082 C CG  . HIS A 1 322 ? 156.773 215.371 129.077 1.00 19.76  ? 330 HIS A CG  1 
ATOM   2083 N ND1 . HIS A 1 322 ? 156.235 214.650 128.027 1.00 20.96  ? 330 HIS A ND1 1 
ATOM   2084 C CD2 . HIS A 1 322 ? 155.733 215.795 129.809 1.00 20.04  ? 330 HIS A CD2 1 
ATOM   2085 C CE1 . HIS A 1 322 ? 154.933 214.655 128.129 1.00 21.19  ? 330 HIS A CE1 1 
ATOM   2086 N NE2 . HIS A 1 322 ? 154.600 215.344 129.196 1.00 22.60  ? 330 HIS A NE2 1 
ATOM   2087 N N   . CYS A 1 323 ? 158.785 215.176 132.307 1.00 17.03  ? 331 CYS A N   1 
ATOM   2088 C CA  . CYS A 1 323 ? 158.276 215.300 133.684 1.00 15.21  ? 331 CYS A CA  1 
ATOM   2089 C C   . CYS A 1 323 ? 157.691 216.686 133.938 1.00 15.16  ? 331 CYS A C   1 
ATOM   2090 O O   . CYS A 1 323 ? 158.207 217.704 133.483 1.00 17.94  ? 331 CYS A O   1 
ATOM   2091 C CB  . CYS A 1 323 ? 159.358 214.994 134.741 1.00 12.73  ? 331 CYS A CB  1 
ATOM   2092 S SG  . CYS A 1 323 ? 160.029 213.349 134.692 1.00 14.73  ? 331 CYS A SG  1 
ATOM   2093 N N   . ASN A 1 324 ? 156.615 216.728 134.706 1.00 18.01  ? 332 ASN A N   1 
ATOM   2094 C CA  . ASN A 1 324 ? 155.932 217.960 135.075 1.00 18.09  ? 332 ASN A CA  1 
ATOM   2095 C C   . ASN A 1 324 ? 156.014 218.257 136.578 1.00 18.42  ? 332 ASN A C   1 
ATOM   2096 O O   . ASN A 1 324 ? 155.621 217.431 137.411 1.00 18.25  ? 332 ASN A O   1 
ATOM   2097 C CB  . ASN A 1 324 ? 154.462 217.926 134.641 1.00 19.86  ? 332 ASN A CB  1 
ATOM   2098 C CG  . ASN A 1 324 ? 154.220 218.256 133.166 1.00 20.67  ? 332 ASN A CG  1 
ATOM   2099 O OD1 . ASN A 1 324 ? 155.154 218.465 132.366 1.00 21.65  ? 332 ASN A OD1 1 
ATOM   2100 N ND2 . ASN A 1 324 ? 152.947 218.286 132.817 1.00 25.54  ? 332 ASN A ND2 1 
ATOM   2101 N N   . VAL A 1 325 ? 156.515 219.466 136.917 1.00 19.23  ? 333 VAL A N   1 
ATOM   2102 C CA  . VAL A 1 325 ? 156.639 219.994 138.285 1.00 17.94  ? 333 VAL A CA  1 
ATOM   2103 C C   . VAL A 1 325 ? 155.795 221.262 138.392 1.00 19.75  ? 333 VAL A C   1 
ATOM   2104 O O   . VAL A 1 325 ? 155.946 222.164 137.580 1.00 23.31  ? 333 VAL A O   1 
ATOM   2105 C CB  . VAL A 1 325 ? 158.117 220.307 138.595 1.00 17.33  ? 333 VAL A CB  1 
ATOM   2106 C CG1 . VAL A 1 325 ? 158.262 220.873 139.943 1.00 16.70  ? 333 VAL A CG1 1 
ATOM   2107 C CG2 . VAL A 1 325 ? 158.919 219.054 138.499 1.00 17.84  ? 333 VAL A CG2 1 
ATOM   2108 N N   . SER A 1 326 ? 154.895 221.360 139.370 1.00 21.32  ? 334 SER A N   1 
ATOM   2109 C CA  . SER A 1 326 ? 154.075 222.576 139.472 1.00 20.10  ? 334 SER A CA  1 
ATOM   2110 C C   . SER A 1 326 ? 154.952 223.799 139.570 1.00 19.03  ? 334 SER A C   1 
ATOM   2111 O O   . SER A 1 326 ? 155.873 223.839 140.390 1.00 21.45  ? 334 SER A O   1 
ATOM   2112 C CB  . SER A 1 326 ? 153.174 222.494 140.671 1.00 20.97  ? 334 SER A CB  1 
ATOM   2113 O OG  . SER A 1 326 ? 152.567 223.732 140.937 1.00 23.11  ? 334 SER A OG  1 
ATOM   2114 N N   . LYS A 1 327 ? 154.660 224.824 138.770 1.00 21.01  ? 335 LYS A N   1 
ATOM   2115 C CA  . LYS A 1 327 ? 155.531 225.985 138.779 1.00 20.59  ? 335 LYS A CA  1 
ATOM   2116 C C   . LYS A 1 327 ? 155.489 226.724 140.093 1.00 22.06  ? 335 LYS A C   1 
ATOM   2117 O O   . LYS A 1 327 ? 156.524 227.176 140.592 1.00 22.57  ? 335 LYS A O   1 
ATOM   2118 C CB  . LYS A 1 327 ? 155.200 226.934 137.632 1.00 26.11  ? 335 LYS A CB  1 
ATOM   2119 C CG  . LYS A 1 327 ? 156.164 228.133 137.526 1.00 28.78  ? 335 LYS A CG  1 
ATOM   2120 C CD  . LYS A 1 327 ? 155.983 228.932 136.211 1.00 36.82  ? 335 LYS A CD  1 
ATOM   2121 C CE  . LYS A 1 327 ? 154.757 229.851 136.241 1.00 43.96  ? 335 LYS A CE  1 
ATOM   2122 N NZ  . LYS A 1 327 ? 154.602 230.645 134.980 1.00 48.76  ? 335 LYS A NZ  1 
ATOM   2123 N N   . ALA A 1 328 ? 154.288 226.901 140.645 1.00 23.97  ? 336 ALA A N   1 
ATOM   2124 C CA  . ALA A 1 328 ? 154.162 227.628 141.891 1.00 21.29  ? 336 ALA A CA  1 
ATOM   2125 C C   . ALA A 1 328 ? 154.774 226.876 143.048 1.00 20.70  ? 336 ALA A C   1 
ATOM   2126 O O   . ALA A 1 328 ? 155.452 227.483 143.880 1.00 23.71  ? 336 ALA A O   1 
ATOM   2127 C CB  . ALA A 1 328 ? 152.708 227.893 142.190 1.00 22.80  ? 336 ALA A CB  1 
ATOM   2128 N N   . THR A 1 329 ? 154.589 225.556 143.082 1.00 20.22  ? 337 THR A N   1 
ATOM   2129 C CA  . THR A 1 329 ? 155.106 224.786 144.193 1.00 18.40  ? 337 THR A CA  1 
ATOM   2130 C C   . THR A 1 329 ? 156.614 224.836 144.165 1.00 17.30  ? 337 THR A C   1 
ATOM   2131 O O   . THR A 1 329 ? 157.267 224.980 145.205 1.00 20.45  ? 337 THR A O   1 
ATOM   2132 C CB  . THR A 1 329 ? 154.624 223.331 144.152 1.00 18.57  ? 337 THR A CB  1 
ATOM   2133 O OG1 . THR A 1 329 ? 153.191 223.291 144.206 1.00 20.35  ? 337 THR A OG1 1 
ATOM   2134 C CG2 . THR A 1 329 ? 155.152 222.600 145.347 1.00 18.78  ? 337 THR A CG2 1 
ATOM   2135 N N   . TRP A 1 330 ? 157.188 224.691 142.980 1.00 17.83  ? 338 TRP A N   1 
ATOM   2136 C CA  . TRP A 1 330 ? 158.623 224.744 142.860 1.00 16.18  ? 338 TRP A CA  1 
ATOM   2137 C C   . TRP A 1 330 ? 159.205 226.099 143.294 1.00 16.66  ? 338 TRP A C   1 
ATOM   2138 O O   . TRP A 1 330 ? 160.241 226.107 143.967 1.00 18.80  ? 338 TRP A O   1 
ATOM   2139 C CB  . TRP A 1 330 ? 159.073 224.377 141.468 1.00 14.40  ? 338 TRP A CB  1 
ATOM   2140 C CG  . TRP A 1 330 ? 160.518 224.345 141.361 1.00 11.40  ? 338 TRP A CG  1 
ATOM   2141 C CD1 . TRP A 1 330 ? 161.280 225.192 140.684 1.00 10.00  ? 338 TRP A CD1 1 
ATOM   2142 C CD2 . TRP A 1 330 ? 161.414 223.403 141.964 1.00 9.71   ? 338 TRP A CD2 1 
ATOM   2143 N NE1 . TRP A 1 330 ? 162.562 224.856 140.816 1.00 10.27  ? 338 TRP A NE1 1 
ATOM   2144 C CE2 . TRP A 1 330 ? 162.664 223.774 141.601 1.00 8.92   ? 338 TRP A CE2 1 
ATOM   2145 C CE3 . TRP A 1 330 ? 161.243 222.288 142.774 1.00 9.99   ? 338 TRP A CE3 1 
ATOM   2146 C CZ2 . TRP A 1 330 ? 163.764 223.093 142.004 1.00 10.07  ? 338 TRP A CZ2 1 
ATOM   2147 C CZ3 . TRP A 1 330 ? 162.349 221.596 143.175 1.00 8.17   ? 338 TRP A CZ3 1 
ATOM   2148 C CH2 . TRP A 1 330 ? 163.580 221.998 142.793 1.00 8.58   ? 338 TRP A CH2 1 
ATOM   2149 N N   . ASN A 1 331 ? 158.569 227.252 142.915 1.00 19.37  ? 339 ASN A N   1 
ATOM   2150 C CA  . ASN A 1 331 ? 159.044 228.587 143.299 1.00 21.29  ? 339 ASN A CA  1 
ATOM   2151 C C   . ASN A 1 331 ? 159.002 228.797 144.828 1.00 21.46  ? 339 ASN A C   1 
ATOM   2152 O O   . ASN A 1 331 ? 159.924 229.406 145.385 1.00 22.97  ? 339 ASN A O   1 
ATOM   2153 C CB  . ASN A 1 331 ? 158.240 229.678 142.568 1.00 28.35  ? 339 ASN A CB  1 
ATOM   2154 C CG  . ASN A 1 331 ? 159.042 230.988 142.316 1.00 34.99  ? 339 ASN A CG  1 
ATOM   2155 O OD1 . ASN A 1 331 ? 160.005 230.961 141.527 1.00 35.71  ? 339 ASN A OD1 1 
ATOM   2156 N ND2 . ASN A 1 331 ? 158.638 232.101 142.957 1.00 37.90  ? 339 ASN A ND2 1 
ATOM   2157 N N   . GLU A 1 332 ? 157.967 228.234 145.536 1.00 21.30  ? 340 GLU A N   1 
ATOM   2158 C CA  . GLU A 1 332 ? 157.853 228.283 147.003 1.00 19.79  ? 340 GLU A CA  1 
ATOM   2159 C C   . GLU A 1 332 ? 158.972 227.473 147.637 1.00 19.06  ? 340 GLU A C   1 
ATOM   2160 O O   . GLU A 1 332 ? 159.594 227.912 148.609 1.00 21.76  ? 340 GLU A O   1 
ATOM   2161 C CB  . GLU A 1 332 ? 156.529 227.696 147.476 1.00 21.18  ? 340 GLU A CB  1 
ATOM   2162 C CG  . GLU A 1 332 ? 155.311 228.497 147.146 1.00 25.84  ? 340 GLU A CG  1 
ATOM   2163 C CD  . GLU A 1 332 ? 154.055 227.798 147.574 1.00 31.44  ? 340 GLU A CD  1 
ATOM   2164 O OE1 . GLU A 1 332 ? 154.155 226.693 148.051 1.00 29.37  ? 340 GLU A OE1 1 
ATOM   2165 O OE2 . GLU A 1 332 ? 152.998 228.361 147.423 1.00 39.48  ? 340 GLU A OE2 1 
ATOM   2166 N N   . THR A 1 333 ? 159.269 226.326 147.029 1.00 20.15  ? 341 THR A N   1 
ATOM   2167 C CA  . THR A 1 333 ? 160.313 225.446 147.499 1.00 17.74  ? 341 THR A CA  1 
ATOM   2168 C C   . THR A 1 333 ? 161.647 226.130 147.427 1.00 16.82  ? 341 THR A C   1 
ATOM   2169 O O   . THR A 1 333 ? 162.401 226.105 148.400 1.00 19.58  ? 341 THR A O   1 
ATOM   2170 C CB  . THR A 1 333 ? 160.351 224.151 146.668 1.00 17.21  ? 341 THR A CB  1 
ATOM   2171 O OG1 . THR A 1 333 ? 159.111 223.465 146.824 1.00 18.05  ? 341 THR A OG1 1 
ATOM   2172 C CG2 . THR A 1 333 ? 161.486 223.258 147.094 1.00 16.82  ? 341 THR A CG2 1 
ATOM   2173 N N   . LEU A 1 334 ? 161.948 226.778 146.306 1.00 18.24  ? 342 LEU A N   1 
ATOM   2174 C CA  . LEU A 1 334 ? 163.227 227.439 146.239 1.00 16.72  ? 342 LEU A CA  1 
ATOM   2175 C C   . LEU A 1 334 ? 163.286 228.612 147.174 1.00 16.39  ? 342 LEU A C   1 
ATOM   2176 O O   . LEU A 1 334 ? 164.320 228.833 147.794 1.00 21.66  ? 342 LEU A O   1 
ATOM   2177 C CB  . LEU A 1 334 ? 163.574 227.902 144.842 1.00 18.28  ? 342 LEU A CB  1 
ATOM   2178 C CG  . LEU A 1 334 ? 163.878 226.844 143.794 1.00 15.02  ? 342 LEU A CG  1 
ATOM   2179 C CD1 . LEU A 1 334 ? 164.081 227.560 142.503 1.00 15.34  ? 342 LEU A CD1 1 
ATOM   2180 C CD2 . LEU A 1 334 ? 165.128 226.016 144.157 1.00 14.62  ? 342 LEU A CD2 1 
ATOM   2181 N N   . GLY A 1 335 ? 162.194 229.345 147.363 1.00 19.17  ? 343 GLY A N   1 
ATOM   2182 C CA  . GLY A 1 335 ? 162.274 230.466 148.280 1.00 18.49  ? 343 GLY A CA  1 
ATOM   2183 C C   . GLY A 1 335 ? 162.690 229.986 149.669 1.00 16.75  ? 343 GLY A C   1 
ATOM   2184 O O   . GLY A 1 335 ? 163.534 230.611 150.315 1.00 20.54  ? 343 GLY A O   1 
ATOM   2185 N N   . LYS A 1 336 ? 162.144 228.849 150.112 1.00 17.29  ? 344 LYS A N   1 
ATOM   2186 C CA  . LYS A 1 336 ? 162.517 228.295 151.407 1.00 16.14  ? 344 LYS A CA  1 
ATOM   2187 C C   . LYS A 1 336 ? 163.985 227.868 151.460 1.00 15.19  ? 344 LYS A C   1 
ATOM   2188 O O   . LYS A 1 336 ? 164.673 228.128 152.451 1.00 18.67  ? 344 LYS A O   1 
ATOM   2189 C CB  . LYS A 1 336 ? 161.621 227.124 151.746 1.00 15.43  ? 344 LYS A CB  1 
ATOM   2190 C CG  . LYS A 1 336 ? 160.205 227.524 152.063 1.00 15.60  ? 344 LYS A CG  1 
ATOM   2191 C CD  . LYS A 1 336 ? 159.386 226.372 152.597 1.00 15.42  ? 344 LYS A CD  1 
ATOM   2192 C CE  . LYS A 1 336 ? 158.993 225.411 151.509 1.00 20.02  ? 344 LYS A CE  1 
ATOM   2193 N NZ  . LYS A 1 336 ? 158.088 224.361 152.010 1.00 22.57  ? 344 LYS A NZ  1 
ATOM   2194 N N   . VAL A 1 337 ? 164.489 227.285 150.374 1.00 17.23  ? 345 VAL A N   1 
ATOM   2195 C CA  . VAL A 1 337 ? 165.879 226.852 150.321 1.00 15.59  ? 345 VAL A CA  1 
ATOM   2196 C C   . VAL A 1 337 ? 166.799 228.061 150.420 1.00 15.51  ? 345 VAL A C   1 
ATOM   2197 O O   . VAL A 1 337 ? 167.794 228.015 151.138 1.00 17.23  ? 345 VAL A O   1 
ATOM   2198 C CB  . VAL A 1 337 ? 166.169 226.052 149.033 1.00 15.13  ? 345 VAL A CB  1 
ATOM   2199 C CG1 . VAL A 1 337 ? 167.666 225.757 148.895 1.00 14.30  ? 345 VAL A CG1 1 
ATOM   2200 C CG2 . VAL A 1 337 ? 165.391 224.757 149.061 1.00 14.61  ? 345 VAL A CG2 1 
ATOM   2201 N N   . VAL A 1 338 ? 166.456 229.137 149.720 1.00 17.25  ? 346 VAL A N   1 
ATOM   2202 C CA  . VAL A 1 338 ? 167.228 230.370 149.713 1.00 17.14  ? 346 VAL A CA  1 
ATOM   2203 C C   . VAL A 1 338 ? 167.283 230.985 151.103 1.00 17.55  ? 346 VAL A C   1 
ATOM   2204 O O   . VAL A 1 338 ? 168.355 231.396 151.556 1.00 19.69  ? 346 VAL A O   1 
ATOM   2205 C CB  . VAL A 1 338 ? 166.604 231.343 148.702 1.00 18.12  ? 346 VAL A CB  1 
ATOM   2206 C CG1 . VAL A 1 338 ? 167.204 232.716 148.778 1.00 20.25  ? 346 VAL A CG1 1 
ATOM   2207 C CG2 . VAL A 1 338 ? 166.833 230.799 147.336 1.00 19.07  ? 346 VAL A CG2 1 
ATOM   2208 N N   . LYS A 1 339 ? 166.155 231.022 151.811 1.00 18.76  ? 347 LYS A N   1 
ATOM   2209 C CA  . LYS A 1 339 ? 166.164 231.576 153.156 1.00 17.96  ? 347 LYS A CA  1 
ATOM   2210 C C   . LYS A 1 339 ? 167.130 230.838 154.064 1.00 17.54  ? 347 LYS A C   1 
ATOM   2211 O O   . LYS A 1 339 ? 167.780 231.462 154.903 1.00 19.27  ? 347 LYS A O   1 
ATOM   2212 C CB  . LYS A 1 339 ? 164.775 231.532 153.776 1.00 20.38  ? 347 LYS A CB  1 
ATOM   2213 C CG  . LYS A 1 339 ? 163.797 232.510 153.186 1.00 26.20  ? 347 LYS A CG  1 
ATOM   2214 C CD  . LYS A 1 339 ? 162.419 232.377 153.827 1.00 35.57  ? 347 LYS A CD  1 
ATOM   2215 C CE  . LYS A 1 339 ? 161.422 233.336 153.191 1.00 52.00  ? 347 LYS A CE  1 
ATOM   2216 N NZ  . LYS A 1 339 ? 160.059 233.193 153.775 1.00 67.05  ? 347 LYS A NZ  1 
ATOM   2217 N N   . GLN A 1 340 ? 167.223 229.520 153.913 1.00 17.62  ? 348 GLN A N   1 
ATOM   2218 C CA  . GLN A 1 340 ? 168.117 228.751 154.757 1.00 15.60  ? 348 GLN A CA  1 
ATOM   2219 C C   . GLN A 1 340 ? 169.572 228.866 154.286 1.00 15.39  ? 348 GLN A C   1 
ATOM   2220 O O   . GLN A 1 340 ? 170.490 228.891 155.099 1.00 19.04  ? 348 GLN A O   1 
ATOM   2221 C CB  . GLN A 1 340 ? 167.678 227.300 154.785 1.00 16.08  ? 348 GLN A CB  1 
ATOM   2222 C CG  . GLN A 1 340 ? 166.293 227.031 155.345 1.00 16.60  ? 348 GLN A CG  1 
ATOM   2223 C CD  . GLN A 1 340 ? 166.021 227.411 156.788 1.00 19.40  ? 348 GLN A CD  1 
ATOM   2224 O OE1 . GLN A 1 340 ? 166.121 228.567 157.212 1.00 20.78  ? 348 GLN A OE1 1 
ATOM   2225 N NE2 . GLN A 1 340 ? 165.640 226.417 157.560 1.00 23.53  ? 348 GLN A NE2 1 
ATOM   2226 N N   . LEU A 1 341 ? 169.811 229.002 152.987 1.00 16.99  ? 349 LEU A N   1 
ATOM   2227 C CA  . LEU A 1 341 ? 171.182 229.156 152.502 1.00 17.69  ? 349 LEU A CA  1 
ATOM   2228 C C   . LEU A 1 341 ? 171.775 230.440 153.047 1.00 19.79  ? 349 LEU A C   1 
ATOM   2229 O O   . LEU A 1 341 ? 172.939 230.469 153.451 1.00 24.50  ? 349 LEU A O   1 
ATOM   2230 C CB  . LEU A 1 341 ? 171.231 229.156 150.969 1.00 16.99  ? 349 LEU A CB  1 
ATOM   2231 C CG  . LEU A 1 341 ? 170.997 227.821 150.234 1.00 15.10  ? 349 LEU A CG  1 
ATOM   2232 C CD1 . LEU A 1 341 ? 170.799 228.098 148.771 1.00 15.70  ? 349 LEU A CD1 1 
ATOM   2233 C CD2 . LEU A 1 341 ? 172.225 226.913 150.398 1.00 14.77  ? 349 LEU A CD2 1 
ATOM   2234 N N   . ARG A 1 342 ? 170.957 231.470 153.186 1.00 20.12  ? 350 ARG A N   1 
ATOM   2235 C CA  . ARG A 1 342 ? 171.403 232.765 153.698 1.00 19.16  ? 350 ARG A CA  1 
ATOM   2236 C C   . ARG A 1 342 ? 171.815 232.741 155.169 1.00 23.45  ? 350 ARG A C   1 
ATOM   2237 O O   . ARG A 1 342 ? 172.262 233.745 155.707 1.00 27.30  ? 350 ARG A O   1 
ATOM   2238 C CB  . ARG A 1 342 ? 170.352 233.813 153.508 1.00 22.46  ? 350 ARG A CB  1 
ATOM   2239 C CG  . ARG A 1 342 ? 170.156 234.194 152.113 1.00 24.58  ? 350 ARG A CG  1 
ATOM   2240 C CD  . ARG A 1 342 ? 169.154 235.181 151.978 1.00 24.14  ? 350 ARG A CD  1 
ATOM   2241 N NE  . ARG A 1 342 ? 168.948 235.532 150.607 1.00 26.62  ? 350 ARG A NE  1 
ATOM   2242 C CZ  . ARG A 1 342 ? 168.009 236.368 150.201 1.00 30.11  ? 350 ARG A CZ  1 
ATOM   2243 N NH1 . ARG A 1 342 ? 167.208 236.934 151.053 1.00 34.11  ? 350 ARG A NH1 1 
ATOM   2244 N NH2 . ARG A 1 342 ? 167.843 236.665 148.951 1.00 32.57  ? 350 ARG A NH2 1 
ATOM   2245 N N   . LYS A 1 343 ? 171.632 231.615 155.851 1.00 21.98  ? 351 LYS A N   1 
ATOM   2246 C CA  . LYS A 1 343 ? 172.073 231.505 157.223 1.00 19.85  ? 351 LYS A CA  1 
ATOM   2247 C C   . LYS A 1 343 ? 173.521 231.031 157.282 1.00 21.78  ? 351 LYS A C   1 
ATOM   2248 O O   . LYS A 1 343 ? 174.136 231.050 158.349 1.00 24.22  ? 351 LYS A O   1 
ATOM   2249 C CB  . LYS A 1 343 ? 171.149 230.577 157.995 1.00 19.30  ? 351 LYS A CB  1 
ATOM   2250 C CG  . LYS A 1 343 ? 169.765 231.151 158.167 1.00 18.86  ? 351 LYS A CG  1 
ATOM   2251 C CD  . LYS A 1 343 ? 168.820 230.203 158.862 1.00 17.18  ? 351 LYS A CD  1 
ATOM   2252 C CE  . LYS A 1 343 ? 167.482 230.896 159.143 1.00 21.37  ? 351 LYS A CE  1 
ATOM   2253 N NZ  . LYS A 1 343 ? 166.446 229.958 159.638 1.00 25.29  ? 351 LYS A NZ  1 
ATOM   2254 N N   . HIS A 1 344 ? 174.061 230.594 156.136 1.00 21.01  ? 352 HIS A N   1 
ATOM   2255 C CA  . HIS A 1 344 ? 175.435 230.108 156.039 1.00 23.26  ? 352 HIS A CA  1 
ATOM   2256 C C   . HIS A 1 344 ? 176.250 231.039 155.169 1.00 23.08  ? 352 HIS A C   1 
ATOM   2257 O O   . HIS A 1 344 ? 177.472 231.159 155.302 1.00 24.64  ? 352 HIS A O   1 
ATOM   2258 C CB  . HIS A 1 344 ? 175.456 228.724 155.426 1.00 22.14  ? 352 HIS A CB  1 
ATOM   2259 C CG  . HIS A 1 344 ? 174.704 227.775 156.219 1.00 22.51  ? 352 HIS A CG  1 
ATOM   2260 N ND1 . HIS A 1 344 ? 175.126 227.354 157.439 1.00 23.42  ? 352 HIS A ND1 1 
ATOM   2261 C CD2 . HIS A 1 344 ? 173.527 227.161 155.992 1.00 21.09  ? 352 HIS A CD2 1 
ATOM   2262 C CE1 . HIS A 1 344 ? 174.247 226.535 157.939 1.00 23.37  ? 352 HIS A CE1 1 
ATOM   2263 N NE2 . HIS A 1 344 ? 173.266 226.391 157.079 1.00 20.70  ? 352 HIS A NE2 1 
ATOM   2264 N N   . PHE A 1 345 ? 175.541 231.720 154.294 1.00 24.90  ? 353 PHE A N   1 
ATOM   2265 C CA  . PHE A 1 345 ? 176.080 232.655 153.338 1.00 25.54  ? 353 PHE A CA  1 
ATOM   2266 C C   . PHE A 1 345 ? 175.613 234.008 153.836 1.00 27.33  ? 353 PHE A C   1 
ATOM   2267 O O   . PHE A 1 345 ? 175.086 234.085 154.938 1.00 27.95  ? 353 PHE A O   1 
ATOM   2268 C CB  . PHE A 1 345 ? 175.651 232.281 151.913 1.00 24.41  ? 353 PHE A CB  1 
ATOM   2269 C CG  . PHE A 1 345 ? 176.195 230.897 151.566 1.00 23.30  ? 353 PHE A CG  1 
ATOM   2270 C CD1 . PHE A 1 345 ? 177.538 230.711 151.349 1.00 23.38  ? 353 PHE A CD1 1 
ATOM   2271 C CD2 . PHE A 1 345 ? 175.382 229.777 151.551 1.00 21.39  ? 353 PHE A CD2 1 
ATOM   2272 C CE1 . PHE A 1 345 ? 178.045 229.464 151.132 1.00 23.02  ? 353 PHE A CE1 1 
ATOM   2273 C CE2 . PHE A 1 345 ? 175.898 228.528 151.327 1.00 20.72  ? 353 PHE A CE2 1 
ATOM   2274 C CZ  . PHE A 1 345 ? 177.225 228.375 151.125 1.00 21.68  ? 353 PHE A CZ  1 
ATOM   2275 N N   . GLY A 1 346 ? 175.918 235.094 153.159 1.00 30.45  ? 354 GLY A N   1 
ATOM   2276 C CA  . GLY A 1 346 ? 175.506 236.364 153.750 1.00 33.26  ? 354 GLY A CA  1 
ATOM   2277 C C   . GLY A 1 346 ? 173.999 236.544 153.641 1.00 33.53  ? 354 GLY A C   1 
ATOM   2278 O O   . GLY A 1 346 ? 173.359 235.849 152.858 1.00 32.75  ? 354 GLY A O   1 
ATOM   2279 N N   . ASN A 1 347 ? 173.434 237.519 154.400 1.00 36.30  ? 355 ASN A N   1 
ATOM   2280 C CA  . ASN A 1 347 ? 171.997 237.850 154.367 1.00 37.85  ? 355 ASN A CA  1 
ATOM   2281 C C   . ASN A 1 347 ? 171.673 238.773 153.178 1.00 39.28  ? 355 ASN A C   1 
ATOM   2282 O O   . ASN A 1 347 ? 170.770 238.491 152.382 1.00 39.55  ? 355 ASN A O   1 
ATOM   2283 C CB  . ASN A 1 347 ? 171.557 238.491 155.714 1.00 43.97  ? 355 ASN A CB  1 
ATOM   2284 C CG  . ASN A 1 347 ? 170.230 237.919 156.329 1.00 42.59  ? 355 ASN A CG  1 
ATOM   2285 O OD1 . ASN A 1 347 ? 169.573 237.027 155.758 1.00 40.89  ? 355 ASN A OD1 1 
ATOM   2286 N ND2 . ASN A 1 347 ? 169.869 238.455 157.501 1.00 51.42  ? 355 ASN A ND2 1 
ATOM   2287 N N   . ASN A 1 348 ? 172.467 239.860 152.991 1.00 42.53  ? 356 ASN A N   1 
ATOM   2288 C CA  . ASN A 1 348 ? 172.311 240.827 151.895 1.00 45.76  ? 356 ASN A CA  1 
ATOM   2289 C C   . ASN A 1 348 ? 173.143 240.313 150.734 1.00 42.37  ? 356 ASN A C   1 
ATOM   2290 O O   . ASN A 1 348 ? 174.165 240.893 150.362 1.00 43.34  ? 356 ASN A O   1 
ATOM   2291 C CB  . ASN A 1 348 ? 172.740 242.216 152.329 1.00 51.42  ? 356 ASN A CB  1 
ATOM   2292 C CG  . ASN A 1 348 ? 172.343 243.269 151.346 1.00 51.20  ? 356 ASN A CG  1 
ATOM   2293 O OD1 . ASN A 1 348 ? 171.458 243.046 150.516 1.00 52.22  ? 356 ASN A OD1 1 
ATOM   2294 N ND2 . ASN A 1 348 ? 172.972 244.416 151.424 1.00 58.38  ? 356 ASN A ND2 1 
ATOM   2295 N N   . THR A 1 349 ? 172.699 239.190 150.206 1.00 42.83  ? 357 THR A N   1 
ATOM   2296 C CA  . THR A 1 349 ? 173.408 238.468 149.166 1.00 39.48  ? 357 THR A CA  1 
ATOM   2297 C C   . THR A 1 349 ? 172.521 238.096 148.015 1.00 37.95  ? 357 THR A C   1 
ATOM   2298 O O   . THR A 1 349 ? 171.312 238.379 148.004 1.00 40.37  ? 357 THR A O   1 
ATOM   2299 C CB  . THR A 1 349 ? 174.034 237.178 149.716 1.00 35.88  ? 357 THR A CB  1 
ATOM   2300 O OG1 . THR A 1 349 ? 174.942 236.622 148.747 1.00 35.65  ? 357 THR A OG1 1 
ATOM   2301 C CG2 . THR A 1 349 ? 172.927 236.154 150.008 1.00 32.85  ? 357 THR A CG2 1 
ATOM   2302 N N   . ILE A 1 350 ? 173.152 237.474 147.039 1.00 34.80  ? 358 ILE A N   1 
ATOM   2303 C CA  . ILE A 1 350 ? 172.483 236.976 145.866 1.00 33.92  ? 358 ILE A CA  1 
ATOM   2304 C C   . ILE A 1 350 ? 172.691 235.488 145.720 1.00 31.07  ? 358 ILE A C   1 
ATOM   2305 O O   . ILE A 1 350 ? 173.828 235.003 145.713 1.00 34.63  ? 358 ILE A O   1 
ATOM   2306 C CB  . ILE A 1 350 ? 172.981 237.675 144.599 1.00 37.36  ? 358 ILE A CB  1 
ATOM   2307 C CG1 . ILE A 1 350 ? 172.733 239.167 144.733 1.00 38.46  ? 358 ILE A CG1 1 
ATOM   2308 C CG2 . ILE A 1 350 ? 172.261 237.079 143.388 1.00 35.92  ? 358 ILE A CG2 1 
ATOM   2309 C CD1 . ILE A 1 350 ? 173.318 240.011 143.644 1.00 40.95  ? 358 ILE A CD1 1 
ATOM   2310 N N   . ILE A 1 351 ? 171.590 234.767 145.613 1.00 28.65  ? 359 ILE A N   1 
ATOM   2311 C CA  . ILE A 1 351 ? 171.636 233.338 145.407 1.00 26.95  ? 359 ILE A CA  1 
ATOM   2312 C C   . ILE A 1 351 ? 171.100 232.957 144.052 1.00 28.97  ? 359 ILE A C   1 
ATOM   2313 O O   . ILE A 1 351 ? 169.932 233.156 143.726 1.00 27.03  ? 359 ILE A O   1 
ATOM   2314 C CB  . ILE A 1 351 ? 170.948 232.588 146.556 1.00 25.66  ? 359 ILE A CB  1 
ATOM   2315 C CG1 . ILE A 1 351 ? 171.775 232.875 147.836 1.00 24.66  ? 359 ILE A CG1 1 
ATOM   2316 C CG2 . ILE A 1 351 ? 170.764 231.101 146.235 1.00 23.63  ? 359 ILE A CG2 1 
ATOM   2317 C CD1 . ILE A 1 351 ? 171.215 232.373 149.107 1.00 21.92  ? 359 ILE A CD1 1 
ATOM   2318 N N   . ARG A 1 352 ? 171.964 232.372 143.261 1.00 27.71  ? 360 ARG A N   1 
ATOM   2319 C CA  . ARG A 1 352 ? 171.614 232.005 141.918 1.00 24.58  ? 360 ARG A CA  1 
ATOM   2320 C C   . ARG A 1 352 ? 171.606 230.519 141.708 1.00 23.13  ? 360 ARG A C   1 
ATOM   2321 O O   . ARG A 1 352 ? 172.544 229.823 142.081 1.00 24.17  ? 360 ARG A O   1 
ATOM   2322 C CB  . ARG A 1 352 ? 172.598 232.637 140.969 1.00 28.76  ? 360 ARG A CB  1 
ATOM   2323 C CG  . ARG A 1 352 ? 172.411 232.313 139.512 1.00 31.31  ? 360 ARG A CG  1 
ATOM   2324 C CD  . ARG A 1 352 ? 173.333 233.088 138.717 1.00 34.26  ? 360 ARG A CD  1 
ATOM   2325 N NE  . ARG A 1 352 ? 172.981 234.500 138.751 1.00 41.10  ? 360 ARG A NE  1 
ATOM   2326 C CZ  . ARG A 1 352 ? 173.827 235.522 138.524 1.00 44.83  ? 360 ARG A CZ  1 
ATOM   2327 N NH1 . ARG A 1 352 ? 175.102 235.299 138.247 1.00 48.92  ? 360 ARG A NH1 1 
ATOM   2328 N NH2 . ARG A 1 352 ? 173.372 236.762 138.583 1.00 45.78  ? 360 ARG A NH2 1 
ATOM   2329 N N   . PHE A 1 353 ? 170.573 230.045 141.054 1.00 23.19  ? 361 PHE A N   1 
ATOM   2330 C CA  . PHE A 1 353 ? 170.504 228.650 140.703 1.00 19.51  ? 361 PHE A CA  1 
ATOM   2331 C C   . PHE A 1 353 ? 170.814 228.539 139.232 1.00 22.19  ? 361 PHE A C   1 
ATOM   2332 O O   . PHE A 1 353 ? 170.312 229.317 138.410 1.00 23.35  ? 361 PHE A O   1 
ATOM   2333 C CB  . PHE A 1 353 ? 169.153 228.048 141.039 1.00 19.40  ? 361 PHE A CB  1 
ATOM   2334 C CG  . PHE A 1 353 ? 168.924 227.973 142.503 1.00 19.83  ? 361 PHE A CG  1 
ATOM   2335 C CD1 . PHE A 1 353 ? 169.516 226.988 143.272 1.00 18.65  ? 361 PHE A CD1 1 
ATOM   2336 C CD2 . PHE A 1 353 ? 168.151 228.904 143.119 1.00 20.69  ? 361 PHE A CD2 1 
ATOM   2337 C CE1 . PHE A 1 353 ? 169.321 226.949 144.630 1.00 16.67  ? 361 PHE A CE1 1 
ATOM   2338 C CE2 . PHE A 1 353 ? 167.951 228.865 144.468 1.00 18.92  ? 361 PHE A CE2 1 
ATOM   2339 C CZ  . PHE A 1 353 ? 168.538 227.887 145.227 1.00 17.76  ? 361 PHE A CZ  1 
ATOM   2340 N N   . ALA A 1 354 ? 171.586 227.525 138.897 1.00 20.86  ? 362 ALA A N   1 
ATOM   2341 C CA  . ALA A 1 354 ? 171.999 227.283 137.533 1.00 19.11  ? 362 ALA A CA  1 
ATOM   2342 C C   . ALA A 1 354 ? 172.040 225.796 137.235 1.00 21.19  ? 362 ALA A C   1 
ATOM   2343 O O   . ALA A 1 354 ? 172.080 224.973 138.145 1.00 21.46  ? 362 ALA A O   1 
ATOM   2344 C CB  . ALA A 1 354 ? 173.351 227.917 137.304 1.00 20.49  ? 362 ALA A CB  1 
ATOM   2345 N N   . GLN A 1 355 ? 172.005 225.462 135.951 1.00 20.66  ? 363 GLN A N   1 
ATOM   2346 C CA  . GLN A 1 355 ? 172.037 224.087 135.473 1.00 20.27  ? 363 GLN A CA  1 
ATOM   2347 C C   . GLN A 1 355 ? 173.396 223.439 135.659 1.00 20.79  ? 363 GLN A C   1 
ATOM   2348 O O   . GLN A 1 355 ? 174.410 224.127 135.773 1.00 23.86  ? 363 GLN A O   1 
ATOM   2349 C CB  . GLN A 1 355 ? 171.632 224.051 134.003 1.00 22.36  ? 363 GLN A CB  1 
ATOM   2350 C CG  . GLN A 1 355 ? 172.643 224.648 133.026 1.00 23.82  ? 363 GLN A CG  1 
ATOM   2351 C CD  . GLN A 1 355 ? 172.110 224.611 131.618 1.00 25.20  ? 363 GLN A CD  1 
ATOM   2352 O OE1 . GLN A 1 355 ? 170.930 224.338 131.442 1.00 24.52  ? 363 GLN A OE1 1 
ATOM   2353 N NE2 . GLN A 1 355 ? 172.929 224.876 130.621 1.00 29.38  ? 363 GLN A NE2 1 
ATOM   2354 N N   . SER A 1 356 ? 173.426 222.104 135.689 1.00 21.24  ? 364 SER A N   1 
ATOM   2355 C CA  . SER A 1 356 ? 174.691 221.402 135.858 1.00 23.38  ? 364 SER A CA  1 
ATOM   2356 C C   . SER A 1 356 ? 175.671 221.804 134.776 1.00 28.27  ? 364 SER A C   1 
ATOM   2357 O O   . SER A 1 356 ? 175.320 221.882 133.596 1.00 29.24  ? 364 SER A O   1 
ATOM   2358 C CB  . SER A 1 356 ? 174.497 219.912 135.860 1.00 22.12  ? 364 SER A CB  1 
ATOM   2359 O OG  . SER A 1 356 ? 175.741 219.278 135.908 1.00 27.87  ? 364 SER A OG  1 
ATOM   2360 N N   . SER A 1 357 ? 176.914 222.031 135.196 1.00 30.40  ? 365 SER A N   1 
ATOM   2361 C CA  . SER A 1 357 ? 177.988 222.518 134.346 1.00 34.18  ? 365 SER A CA  1 
ATOM   2362 C C   . SER A 1 357 ? 178.612 221.567 133.332 1.00 36.92  ? 365 SER A C   1 
ATOM   2363 O O   . SER A 1 357 ? 179.208 222.030 132.356 1.00 40.44  ? 365 SER A O   1 
ATOM   2364 C CB  . SER A 1 357 ? 179.089 223.043 135.236 1.00 35.59  ? 365 SER A CB  1 
ATOM   2365 O OG  . SER A 1 357 ? 179.667 222.001 135.972 1.00 38.18  ? 365 SER A OG  1 
ATOM   2366 N N   . GLY A 1 358 ? 178.497 220.263 133.508 1.00 36.51  ? 366 GLY A N   1 
ATOM   2367 C CA  . GLY A 1 358 ? 179.130 219.387 132.536 1.00 39.03  ? 366 GLY A CA  1 
ATOM   2368 C C   . GLY A 1 358 ? 179.208 217.948 132.990 1.00 38.74  ? 366 GLY A C   1 
ATOM   2369 O O   . GLY A 1 358 ? 178.815 217.607 134.106 1.00 38.49  ? 366 GLY A O   1 
ATOM   2370 N N   . GLY A 1 359 ? 179.745 217.102 132.117 1.00 43.34  ? 367 GLY A N   1 
ATOM   2371 C CA  . GLY A 1 359 ? 179.858 215.676 132.383 1.00 42.71  ? 367 GLY A CA  1 
ATOM   2372 C C   . GLY A 1 359 ? 178.905 214.933 131.469 1.00 40.06  ? 367 GLY A C   1 
ATOM   2373 O O   . GLY A 1 359 ? 178.271 215.541 130.605 1.00 39.41  ? 367 GLY A O   1 
ATOM   2374 N N   . ASP A 1 360 ? 178.802 213.625 131.639 1.00 40.95  ? 368 ASP A N   1 
ATOM   2375 C CA  . ASP A 1 360 ? 177.964 212.853 130.742 1.00 38.97  ? 368 ASP A CA  1 
ATOM   2376 C C   . ASP A 1 360 ? 176.501 212.903 131.155 1.00 32.48  ? 368 ASP A C   1 
ATOM   2377 O O   . ASP A 1 360 ? 176.166 213.373 132.247 1.00 31.87  ? 368 ASP A O   1 
ATOM   2378 C CB  . ASP A 1 360 ? 178.468 211.416 130.735 1.00 43.12  ? 368 ASP A CB  1 
ATOM   2379 C CG  . ASP A 1 360 ? 179.845 211.292 130.088 1.00 47.34  ? 368 ASP A CG  1 
ATOM   2380 O OD1 . ASP A 1 360 ? 180.174 212.088 129.241 1.00 51.08  ? 368 ASP A OD1 1 
ATOM   2381 O OD2 . ASP A 1 360 ? 180.570 210.420 130.480 1.00 54.62  ? 368 ASP A OD2 1 
ATOM   2382 N N   . LEU A 1 361 ? 175.645 212.250 130.375 1.00 29.99  ? 369 LEU A N   1 
ATOM   2383 C CA  . LEU A 1 361 ? 174.210 212.286 130.617 1.00 24.45  ? 369 LEU A CA  1 
ATOM   2384 C C   . LEU A 1 361 ? 173.858 211.770 132.000 1.00 20.72  ? 369 LEU A C   1 
ATOM   2385 O O   . LEU A 1 361 ? 172.929 212.259 132.630 1.00 24.07  ? 369 LEU A O   1 
ATOM   2386 C CB  . LEU A 1 361 ? 173.480 211.428 129.569 1.00 23.76  ? 369 LEU A CB  1 
ATOM   2387 C CG  . LEU A 1 361 ? 171.938 211.537 129.505 1.00 16.56  ? 369 LEU A CG  1 
ATOM   2388 C CD1 . LEU A 1 361 ? 171.521 212.924 129.077 1.00 17.24  ? 369 LEU A CD1 1 
ATOM   2389 C CD2 . LEU A 1 361 ? 171.389 210.509 128.568 1.00 16.31  ? 369 LEU A CD2 1 
ATOM   2390 N N   . GLU A 1 362 ? 174.608 210.809 132.506 1.00 24.53  ? 370 GLU A N   1 
ATOM   2391 C CA  . GLU A 1 362 ? 174.350 210.220 133.807 1.00 25.48  ? 370 GLU A CA  1 
ATOM   2392 C C   . GLU A 1 362 ? 174.506 211.179 134.991 1.00 24.12  ? 370 GLU A C   1 
ATOM   2393 O O   . GLU A 1 362 ? 174.057 210.854 136.090 1.00 22.42  ? 370 GLU A O   1 
ATOM   2394 C CB  . GLU A 1 362 ? 175.254 209.004 133.990 1.00 27.81  ? 370 GLU A CB  1 
ATOM   2395 C CG  . GLU A 1 362 ? 174.885 207.816 133.089 1.00 27.63  ? 370 GLU A CG  1 
ATOM   2396 C CD  . GLU A 1 362 ? 175.377 207.927 131.678 1.00 31.70  ? 370 GLU A CD  1 
ATOM   2397 O OE1 . GLU A 1 362 ? 176.103 208.846 131.387 1.00 32.26  ? 370 GLU A OE1 1 
ATOM   2398 O OE2 . GLU A 1 362 ? 175.011 207.091 130.872 1.00 30.45  ? 370 GLU A OE2 1 
ATOM   2399 N N   . VAL A 1 363 ? 175.224 212.295 134.812 1.00 26.05  ? 371 VAL A N   1 
ATOM   2400 C CA  . VAL A 1 363 ? 175.415 213.249 135.902 1.00 23.37  ? 371 VAL A CA  1 
ATOM   2401 C C   . VAL A 1 363 ? 174.870 214.652 135.619 1.00 20.47  ? 371 VAL A C   1 
ATOM   2402 O O   . VAL A 1 363 ? 174.719 215.440 136.546 1.00 21.49  ? 371 VAL A O   1 
ATOM   2403 C CB  . VAL A 1 363 ? 176.896 213.349 136.299 1.00 25.77  ? 371 VAL A CB  1 
ATOM   2404 C CG1 . VAL A 1 363 ? 177.377 211.993 136.789 1.00 27.22  ? 371 VAL A CG1 1 
ATOM   2405 C CG2 . VAL A 1 363 ? 177.726 213.832 135.125 1.00 29.69  ? 371 VAL A CG2 1 
ATOM   2406 N N   . THR A 1 364 ? 174.522 214.962 134.369 1.00 18.65  ? 372 THR A N   1 
ATOM   2407 C CA  . THR A 1 364 ? 174.016 216.292 134.041 1.00 17.33  ? 372 THR A CA  1 
ATOM   2408 C C   . THR A 1 364 ? 172.507 216.346 134.031 1.00 16.24  ? 372 THR A C   1 
ATOM   2409 O O   . THR A 1 364 ? 171.909 217.390 133.758 1.00 17.62  ? 372 THR A O   1 
ATOM   2410 C CB  . THR A 1 364 ? 174.520 216.788 132.687 1.00 21.55  ? 372 THR A CB  1 
ATOM   2411 O OG1 . THR A 1 364 ? 174.093 215.901 131.659 1.00 22.82  ? 372 THR A OG1 1 
ATOM   2412 C CG2 . THR A 1 364 ? 175.985 216.851 132.697 1.00 27.84  ? 372 THR A CG2 1 
ATOM   2413 N N   . THR A 1 365 ? 171.890 215.216 134.306 1.00 15.99  ? 373 THR A N   1 
ATOM   2414 C CA  . THR A 1 365 ? 170.447 215.080 134.301 1.00 10.53  ? 373 THR A CA  1 
ATOM   2415 C C   . THR A 1 365 ? 169.926 214.426 135.550 1.00 9.46   ? 373 THR A C   1 
ATOM   2416 O O   . THR A 1 365 ? 170.679 213.941 136.411 1.00 11.53  ? 373 THR A O   1 
ATOM   2417 C CB  . THR A 1 365 ? 169.919 214.264 133.117 1.00 11.01  ? 373 THR A CB  1 
ATOM   2418 O OG1 . THR A 1 365 ? 170.360 212.927 133.204 1.00 11.42  ? 373 THR A OG1 1 
ATOM   2419 C CG2 . THR A 1 365 ? 170.280 214.841 131.828 1.00 12.74  ? 373 THR A CG2 1 
ATOM   2420 N N   . HIS A 1 366 ? 168.616 214.445 135.661 1.00 8.14   ? 374 HIS A N   1 
ATOM   2421 C CA  . HIS A 1 366 ? 167.940 213.754 136.711 1.00 6.81   ? 374 HIS A CA  1 
ATOM   2422 C C   . HIS A 1 366 ? 167.628 212.359 136.235 1.00 6.31   ? 374 HIS A C   1 
ATOM   2423 O O   . HIS A 1 366 ? 166.784 212.148 135.362 1.00 8.39   ? 374 HIS A O   1 
ATOM   2424 C CB  . HIS A 1 366 ? 166.657 214.452 137.103 1.00 5.98   ? 374 HIS A CB  1 
ATOM   2425 C CG  . HIS A 1 366 ? 165.980 213.808 138.203 1.00 4.36   ? 374 HIS A CG  1 
ATOM   2426 N ND1 . HIS A 1 366 ? 164.630 213.647 138.246 1.00 2.45   ? 374 HIS A ND1 1 
ATOM   2427 C CD2 . HIS A 1 366 ? 166.457 213.300 139.335 1.00 6.15   ? 374 HIS A CD2 1 
ATOM   2428 C CE1 . HIS A 1 366 ? 164.307 213.052 139.357 1.00 3.09   ? 374 HIS A CE1 1 
ATOM   2429 N NE2 . HIS A 1 366 ? 165.409 212.844 140.044 1.00 5.12   ? 374 HIS A NE2 1 
ATOM   2430 N N   . SER A 1 367 ? 168.356 211.412 136.780 1.00 8.13   ? 375 SER A N   1 
ATOM   2431 C CA  . SER A 1 367 ? 168.226 210.034 136.420 1.00 6.56   ? 375 SER A CA  1 
ATOM   2432 C C   . SER A 1 367 ? 167.361 209.311 137.411 1.00 7.60   ? 375 SER A C   1 
ATOM   2433 O O   . SER A 1 367 ? 167.497 209.505 138.624 1.00 11.15  ? 375 SER A O   1 
ATOM   2434 C CB  . SER A 1 367 ? 169.567 209.372 136.318 1.00 7.63   ? 375 SER A CB  1 
ATOM   2435 O OG  . SER A 1 367 ? 169.409 207.995 136.156 1.00 0.00   ? 375 SER A OG  1 
ATOM   2436 N N   . PHE A 1 368 ? 166.398 208.553 136.901 1.00 9.04   ? 376 PHE A N   1 
ATOM   2437 C CA  . PHE A 1 368 ? 165.518 207.733 137.734 1.00 7.89   ? 376 PHE A CA  1 
ATOM   2438 C C   . PHE A 1 368 ? 164.854 206.593 136.954 1.00 8.63   ? 376 PHE A C   1 
ATOM   2439 O O   . PHE A 1 368 ? 164.764 206.609 135.726 1.00 9.73   ? 376 PHE A O   1 
ATOM   2440 C CB  . PHE A 1 368 ? 164.468 208.601 138.423 1.00 7.79   ? 376 PHE A CB  1 
ATOM   2441 C CG  . PHE A 1 368 ? 163.618 209.304 137.497 1.00 6.42   ? 376 PHE A CG  1 
ATOM   2442 C CD1 . PHE A 1 368 ? 164.072 210.433 136.943 1.00 6.44   ? 376 PHE A CD1 1 
ATOM   2443 C CD2 . PHE A 1 368 ? 162.384 208.846 137.131 1.00 8.70   ? 376 PHE A CD2 1 
ATOM   2444 C CE1 . PHE A 1 368 ? 163.376 211.086 136.073 1.00 6.64   ? 376 PHE A CE1 1 
ATOM   2445 C CE2 . PHE A 1 368 ? 161.671 209.551 136.229 1.00 9.20   ? 376 PHE A CE2 1 
ATOM   2446 C CZ  . PHE A 1 368 ? 162.181 210.647 135.707 1.00 8.13   ? 376 PHE A CZ  1 
ATOM   2447 N N   . ASN A 1 369 ? 164.359 205.610 137.684 1.00 11.29  ? 377 ASN A N   1 
ATOM   2448 C CA  . ASN A 1 369 ? 163.598 204.493 137.131 1.00 10.99  ? 377 ASN A CA  1 
ATOM   2449 C C   . ASN A 1 369 ? 162.078 204.731 137.283 1.00 13.72  ? 377 ASN A C   1 
ATOM   2450 O O   . ASN A 1 369 ? 161.599 204.817 138.416 1.00 15.06  ? 377 ASN A O   1 
ATOM   2451 C CB  . ASN A 1 369 ? 164.020 203.195 137.772 1.00 11.82  ? 377 ASN A CB  1 
ATOM   2452 C CG  . ASN A 1 369 ? 163.328 202.044 137.192 1.00 13.83  ? 377 ASN A CG  1 
ATOM   2453 O OD1 . ASN A 1 369 ? 162.114 202.108 136.952 1.00 18.88  ? 377 ASN A OD1 1 
ATOM   2454 N ND2 . ASN A 1 369 ? 164.047 201.002 136.960 1.00 17.13  ? 377 ASN A ND2 1 
ATOM   2455 N N   . CYS A 1 370 ? 161.354 204.917 136.157 1.00 15.76  ? 378 CYS A N   1 
ATOM   2456 C CA  . CYS A 1 370 ? 159.923 205.219 136.092 1.00 17.39  ? 378 CYS A CA  1 
ATOM   2457 C C   . CYS A 1 370 ? 159.171 204.029 135.513 1.00 17.65  ? 378 CYS A C   1 
ATOM   2458 O O   . CYS A 1 370 ? 159.181 203.786 134.303 1.00 20.48  ? 378 CYS A O   1 
ATOM   2459 C CB  . CYS A 1 370 ? 159.679 206.466 135.229 1.00 18.10  ? 378 CYS A CB  1 
ATOM   2460 S SG  . CYS A 1 370 ? 157.954 207.080 135.127 1.00 21.52  ? 378 CYS A SG  1 
ATOM   2461 N N   . GLY A 1 371 ? 158.614 203.211 136.369 1.00 19.28  ? 379 GLY A N   1 
ATOM   2462 C CA  . GLY A 1 371 ? 157.862 202.084 135.869 1.00 21.52  ? 379 GLY A CA  1 
ATOM   2463 C C   . GLY A 1 371 ? 158.712 201.031 135.190 1.00 20.87  ? 379 GLY A C   1 
ATOM   2464 O O   . GLY A 1 371 ? 158.194 200.284 134.375 1.00 21.88  ? 379 GLY A O   1 
ATOM   2465 N N   . GLY A 1 372 ? 160.003 200.957 135.501 1.00 19.37  ? 380 GLY A N   1 
ATOM   2466 C CA  . GLY A 1 372 ? 160.908 200.031 134.864 1.00 18.15  ? 380 GLY A CA  1 
ATOM   2467 C C   . GLY A 1 372 ? 161.749 200.658 133.749 1.00 16.96  ? 380 GLY A C   1 
ATOM   2468 O O   . GLY A 1 372 ? 162.738 200.060 133.331 1.00 17.71  ? 380 GLY A O   1 
ATOM   2469 N N   . GLU A 1 373 ? 161.402 201.856 133.278 1.00 16.52  ? 381 GLU A N   1 
ATOM   2470 C CA  . GLU A 1 373 ? 162.210 202.484 132.234 1.00 14.94  ? 381 GLU A CA  1 
ATOM   2471 C C   . GLU A 1 373 ? 163.189 203.457 132.852 1.00 13.12  ? 381 GLU A C   1 
ATOM   2472 O O   . GLU A 1 373 ? 162.907 204.072 133.877 1.00 17.08  ? 381 GLU A O   1 
ATOM   2473 C CB  . GLU A 1 373 ? 161.351 203.198 131.202 1.00 16.64  ? 381 GLU A CB  1 
ATOM   2474 C CG  . GLU A 1 373 ? 160.424 202.313 130.379 1.00 20.51  ? 381 GLU A CG  1 
ATOM   2475 C CD  . GLU A 1 373 ? 161.108 201.401 129.351 1.00 24.10  ? 381 GLU A CD  1 
ATOM   2476 O OE1 . GLU A 1 373 ? 162.291 201.515 129.215 1.00 58.21  ? 381 GLU A OE1 1 
ATOM   2477 O OE2 . GLU A 1 373 ? 160.431 200.607 128.669 1.00 22.98  ? 381 GLU A OE2 1 
ATOM   2478 N N   . PHE A 1 374 ? 164.320 203.666 132.205 1.00 11.83  ? 382 PHE A N   1 
ATOM   2479 C CA  . PHE A 1 374 ? 165.304 204.591 132.739 1.00 9.50   ? 382 PHE A CA  1 
ATOM   2480 C C   . PHE A 1 374 ? 165.325 205.921 132.006 1.00 9.88   ? 382 PHE A C   1 
ATOM   2481 O O   . PHE A 1 374 ? 165.714 206.013 130.837 1.00 11.28  ? 382 PHE A O   1 
ATOM   2482 C CB  . PHE A 1 374 ? 166.668 203.925 132.744 1.00 10.24  ? 382 PHE A CB  1 
ATOM   2483 C CG  . PHE A 1 374 ? 166.762 202.767 133.731 1.00 10.43  ? 382 PHE A CG  1 
ATOM   2484 C CD1 . PHE A 1 374 ? 166.338 201.501 133.396 1.00 12.16  ? 382 PHE A CD1 1 
ATOM   2485 C CD2 . PHE A 1 374 ? 167.285 202.949 134.975 1.00 10.25  ? 382 PHE A CD2 1 
ATOM   2486 C CE1 . PHE A 1 374 ? 166.433 200.457 134.279 1.00 12.95  ? 382 PHE A CE1 1 
ATOM   2487 C CE2 . PHE A 1 374 ? 167.385 201.897 135.862 1.00 10.81  ? 382 PHE A CE2 1 
ATOM   2488 C CZ  . PHE A 1 374 ? 166.957 200.654 135.507 1.00 13.68  ? 382 PHE A CZ  1 
ATOM   2489 N N   . PHE A 1 375 ? 164.915 206.958 132.752 1.00 11.26  ? 383 PHE A N   1 
ATOM   2490 C CA  . PHE A 1 375 ? 164.769 208.346 132.324 1.00 8.67   ? 383 PHE A CA  1 
ATOM   2491 C C   . PHE A 1 375 ? 165.942 209.207 132.710 1.00 8.18   ? 383 PHE A C   1 
ATOM   2492 O O   . PHE A 1 375 ? 166.473 209.082 133.809 1.00 9.55   ? 383 PHE A O   1 
ATOM   2493 C CB  . PHE A 1 375 ? 163.549 208.977 132.976 1.00 9.27   ? 383 PHE A CB  1 
ATOM   2494 C CG  . PHE A 1 375 ? 162.187 208.657 132.451 1.00 11.03  ? 383 PHE A CG  1 
ATOM   2495 C CD1 . PHE A 1 375 ? 161.692 207.394 132.329 1.00 12.21  ? 383 PHE A CD1 1 
ATOM   2496 C CD2 . PHE A 1 375 ? 161.354 209.712 132.133 1.00 12.21  ? 383 PHE A CD2 1 
ATOM   2497 C CE1 . PHE A 1 375 ? 160.408 207.202 131.868 1.00 13.01  ? 383 PHE A CE1 1 
ATOM   2498 C CE2 . PHE A 1 375 ? 160.090 209.525 131.695 1.00 13.37  ? 383 PHE A CE2 1 
ATOM   2499 C CZ  . PHE A 1 375 ? 159.615 208.265 131.560 1.00 13.72  ? 383 PHE A CZ  1 
ATOM   2500 N N   . TYR A 1 376 ? 166.312 210.109 131.806 1.00 9.59   ? 384 TYR A N   1 
ATOM   2501 C CA  . TYR A 1 376 ? 167.368 211.113 131.976 1.00 8.18   ? 384 TYR A CA  1 
ATOM   2502 C C   . TYR A 1 376 ? 166.836 212.513 131.642 1.00 8.40   ? 384 TYR A C   1 
ATOM   2503 O O   . TYR A 1 376 ? 166.865 212.908 130.468 1.00 10.16  ? 384 TYR A O   1 
ATOM   2504 C CB  . TYR A 1 376 ? 168.554 210.742 131.100 1.00 10.07  ? 384 TYR A CB  1 
ATOM   2505 C CG  . TYR A 1 376 ? 169.156 209.441 131.502 1.00 10.19  ? 384 TYR A CG  1 
ATOM   2506 C CD1 . TYR A 1 376 ? 168.626 208.256 131.046 1.00 10.98  ? 384 TYR A CD1 1 
ATOM   2507 C CD2 . TYR A 1 376 ? 170.225 209.426 132.341 1.00 12.29  ? 384 TYR A CD2 1 
ATOM   2508 C CE1 . TYR A 1 376 ? 169.150 207.075 131.463 1.00 11.13  ? 384 TYR A CE1 1 
ATOM   2509 C CE2 . TYR A 1 376 ? 170.756 208.244 132.741 1.00 13.23  ? 384 TYR A CE2 1 
ATOM   2510 C CZ  . TYR A 1 376 ? 170.220 207.073 132.318 1.00 11.43  ? 384 TYR A CZ  1 
ATOM   2511 O OH  . TYR A 1 376 ? 170.760 205.884 132.737 1.00 15.43  ? 384 TYR A OH  1 
ATOM   2512 N N   . CYS A 1 377 ? 166.274 213.220 132.656 1.00 9.19   ? 385 CYS A N   1 
ATOM   2513 C CA  . CYS A 1 377 ? 165.506 214.459 132.498 1.00 9.44   ? 385 CYS A CA  1 
ATOM   2514 C C   . CYS A 1 377 ? 166.347 215.717 132.682 1.00 9.00   ? 385 CYS A C   1 
ATOM   2515 O O   . CYS A 1 377 ? 167.143 215.856 133.613 1.00 11.67  ? 385 CYS A O   1 
ATOM   2516 C CB  . CYS A 1 377 ? 164.316 214.457 133.469 1.00 8.16   ? 385 CYS A CB  1 
ATOM   2517 S SG  . CYS A 1 377 ? 163.193 213.062 133.211 1.00 13.20  ? 385 CYS A SG  1 
ATOM   2518 N N   . ASN A 1 378 ? 166.113 216.672 131.813 1.00 11.34  ? 386 ASN A N   1 
ATOM   2519 C CA  . ASN A 1 378 ? 166.818 217.939 131.838 1.00 11.94  ? 386 ASN A CA  1 
ATOM   2520 C C   . ASN A 1 378 ? 166.107 218.934 132.776 1.00 14.19  ? 386 ASN A C   1 
ATOM   2521 O O   . ASN A 1 378 ? 165.010 219.414 132.482 1.00 15.07  ? 386 ASN A O   1 
ATOM   2522 C CB  . ASN A 1 378 ? 166.986 218.496 130.412 1.00 15.92  ? 386 ASN A CB  1 
ATOM   2523 C CG  . ASN A 1 378 ? 168.072 219.603 130.291 1.00 18.38  ? 386 ASN A CG  1 
ATOM   2524 O OD1 . ASN A 1 378 ? 168.774 219.896 131.279 1.00 19.21  ? 386 ASN A OD1 1 
ATOM   2525 N ND2 . ASN A 1 378 ? 168.203 220.188 129.099 1.00 20.40  ? 386 ASN A ND2 1 
ATOM   2526 N N   . THR A 1 379 ? 166.780 219.281 133.900 1.00 15.34  ? 387 THR A N   1 
ATOM   2527 C CA  . THR A 1 379 ? 166.311 220.094 135.025 1.00 12.51  ? 387 THR A CA  1 
ATOM   2528 C C   . THR A 1 379 ? 166.704 221.552 134.942 1.00 13.22  ? 387 THR A C   1 
ATOM   2529 O O   . THR A 1 379 ? 166.547 222.296 135.910 1.00 16.81  ? 387 THR A O   1 
ATOM   2530 C CB  . THR A 1 379 ? 166.866 219.565 136.312 1.00 11.77  ? 387 THR A CB  1 
ATOM   2531 O OG1 . THR A 1 379 ? 168.274 219.609 136.203 1.00 14.01  ? 387 THR A OG1 1 
ATOM   2532 C CG2 . THR A 1 379 ? 166.379 218.160 136.550 1.00 9.62   ? 387 THR A CG2 1 
ATOM   2533 N N   . SER A 1 380 ? 167.161 221.997 133.788 1.00 15.86  ? 388 SER A N   1 
ATOM   2534 C CA  . SER A 1 380 ? 167.525 223.395 133.602 1.00 15.83  ? 388 SER A CA  1 
ATOM   2535 C C   . SER A 1 380 ? 166.302 224.283 133.764 1.00 17.57  ? 388 SER A C   1 
ATOM   2536 O O   . SER A 1 380 ? 166.414 225.476 134.004 1.00 20.76  ? 388 SER A O   1 
ATOM   2537 C CB  . SER A 1 380 ? 168.067 223.611 132.231 1.00 20.03  ? 388 SER A CB  1 
ATOM   2538 O OG  . SER A 1 380 ? 167.054 223.462 131.282 1.00 21.69  ? 388 SER A OG  1 
ATOM   2539 N N   . GLY A 1 381 ? 165.120 223.699 133.638 1.00 16.01  ? 389 GLY A N   1 
ATOM   2540 C CA  . GLY A 1 381 ? 163.870 224.418 133.813 1.00 15.41  ? 389 GLY A CA  1 
ATOM   2541 C C   . GLY A 1 381 ? 163.528 224.603 135.290 1.00 14.91  ? 389 GLY A C   1 
ATOM   2542 O O   . GLY A 1 381 ? 162.621 225.361 135.628 1.00 16.33  ? 389 GLY A O   1 
ATOM   2543 N N   . LEU A 1 382 ? 164.233 223.889 136.174 1.00 16.00  ? 390 LEU A N   1 
ATOM   2544 C CA  . LEU A 1 382 ? 164.010 223.990 137.609 1.00 12.34  ? 390 LEU A CA  1 
ATOM   2545 C C   . LEU A 1 382 ? 165.069 224.865 138.265 1.00 12.99  ? 390 LEU A C   1 
ATOM   2546 O O   . LEU A 1 382 ? 164.798 225.589 139.226 1.00 14.46  ? 390 LEU A O   1 
ATOM   2547 C CB  . LEU A 1 382 ? 164.070 222.627 138.291 1.00 11.54  ? 390 LEU A CB  1 
ATOM   2548 C CG  . LEU A 1 382 ? 163.099 221.562 137.906 1.00 10.43  ? 390 LEU A CG  1 
ATOM   2549 C CD1 . LEU A 1 382 ? 163.409 220.344 138.741 1.00 8.29   ? 390 LEU A CD1 1 
ATOM   2550 C CD2 . LEU A 1 382 ? 161.676 222.017 138.111 1.00 11.26  ? 390 LEU A CD2 1 
ATOM   2551 N N   . PHE A 1 383 ? 166.278 224.832 137.729 1.00 15.20  ? 391 PHE A N   1 
ATOM   2552 C CA  . PHE A 1 383 ? 167.387 225.564 138.332 1.00 16.28  ? 391 PHE A CA  1 
ATOM   2553 C C   . PHE A 1 383 ? 167.935 226.655 137.426 1.00 17.97  ? 391 PHE A C   1 
ATOM   2554 O O   . PHE A 1 383 ? 169.076 226.583 136.981 1.00 20.67  ? 391 PHE A O   1 
ATOM   2555 C CB  . PHE A 1 383 ? 168.502 224.593 138.699 1.00 16.38  ? 391 PHE A CB  1 
ATOM   2556 C CG  . PHE A 1 383 ? 168.070 223.576 139.699 1.00 15.95  ? 391 PHE A CG  1 
ATOM   2557 C CD1 . PHE A 1 383 ? 168.072 223.860 141.042 1.00 15.22  ? 391 PHE A CD1 1 
ATOM   2558 C CD2 . PHE A 1 383 ? 167.653 222.328 139.293 1.00 14.07  ? 391 PHE A CD2 1 
ATOM   2559 C CE1 . PHE A 1 383 ? 167.673 222.925 141.948 1.00 14.56  ? 391 PHE A CE1 1 
ATOM   2560 C CE2 . PHE A 1 383 ? 167.256 221.389 140.201 1.00 12.22  ? 391 PHE A CE2 1 
ATOM   2561 C CZ  . PHE A 1 383 ? 167.267 221.687 141.523 1.00 12.80  ? 391 PHE A CZ  1 
ATOM   2562 N N   . ASN A 1 384 ? 167.092 227.668 137.152 1.00 21.09  ? 392 ASN A N   1 
ATOM   2563 C CA  . ASN A 1 384 ? 167.382 228.816 136.293 1.00 23.63  ? 392 ASN A CA  1 
ATOM   2564 C C   . ASN A 1 384 ? 166.692 230.072 136.854 1.00 26.48  ? 392 ASN A C   1 
ATOM   2565 O O   . ASN A 1 384 ? 165.635 230.481 136.361 1.00 29.28  ? 392 ASN A O   1 
ATOM   2566 C CB  . ASN A 1 384 ? 166.964 228.498 134.840 1.00 30.08  ? 392 ASN A CB  1 
ATOM   2567 C CG  . ASN A 1 384 ? 167.273 229.602 133.790 1.00 34.35  ? 392 ASN A CG  1 
ATOM   2568 O OD1 . ASN A 1 384 ? 168.428 230.056 133.700 1.00 35.02  ? 392 ASN A OD1 1 
ATOM   2569 N ND2 . ASN A 1 384 ? 166.255 229.994 133.007 1.00 40.65  ? 392 ASN A ND2 1 
ATOM   2570 N N   . SER A 1 385 ? 167.247 230.644 137.960 1.00 26.50  ? 393 SER A N   1 
ATOM   2571 C CA  . SER A 1 385 ? 166.676 231.832 138.654 1.00 25.26  ? 393 SER A CA  1 
ATOM   2572 C C   . SER A 1 385 ? 167.691 232.547 139.529 1.00 25.14  ? 393 SER A C   1 
ATOM   2573 O O   . SER A 1 385 ? 168.647 231.947 140.017 1.00 24.82  ? 393 SER A O   1 
ATOM   2574 C CB  . SER A 1 385 ? 165.455 231.463 139.489 1.00 23.54  ? 393 SER A CB  1 
ATOM   2575 O OG  . SER A 1 385 ? 165.785 230.635 140.562 1.00 23.02  ? 393 SER A OG  1 
ATOM   2576 N N   . THR A 1 386 ? 167.461 233.840 139.774 1.00 27.09  ? 394 THR A N   1 
ATOM   2577 C CA  . THR A 1 386 ? 168.323 234.581 140.689 1.00 26.69  ? 394 THR A CA  1 
ATOM   2578 C C   . THR A 1 386 ? 167.489 235.259 141.762 1.00 28.34  ? 394 THR A C   1 
ATOM   2579 O O   . THR A 1 386 ? 166.547 235.996 141.465 1.00 27.25  ? 394 THR A O   1 
ATOM   2580 C CB  . THR A 1 386 ? 169.171 235.633 139.947 1.00 31.55  ? 394 THR A CB  1 
ATOM   2581 O OG1 . THR A 1 386 ? 169.969 235.001 138.941 1.00 31.50  ? 394 THR A OG1 1 
ATOM   2582 C CG2 . THR A 1 386 ? 170.118 236.271 140.922 1.00 31.16  ? 394 THR A CG2 1 
ATOM   2583 N N   . TRP A 1 387 ? 167.869 235.030 143.011 1.00 29.45  ? 395 TRP A N   1 
ATOM   2584 C CA  . TRP A 1 387 ? 167.200 235.580 144.167 1.00 27.73  ? 395 TRP A CA  1 
ATOM   2585 C C   . TRP A 1 387 ? 168.059 236.679 144.791 1.00 31.79  ? 395 TRP A C   1 
ATOM   2586 O O   . TRP A 1 387 ? 169.116 236.412 145.373 1.00 30.96  ? 395 TRP A O   1 
ATOM   2587 C CB  . TRP A 1 387 ? 166.990 234.441 145.151 1.00 24.86  ? 395 TRP A CB  1 
ATOM   2588 C CG  . TRP A 1 387 ? 166.150 233.344 144.584 1.00 23.04  ? 395 TRP A CG  1 
ATOM   2589 C CD1 . TRP A 1 387 ? 166.600 232.359 143.779 1.00 22.48  ? 395 TRP A CD1 1 
ATOM   2590 C CD2 . TRP A 1 387 ? 164.759 233.065 144.792 1.00 21.04  ? 395 TRP A CD2 1 
ATOM   2591 N NE1 . TRP A 1 387 ? 165.594 231.519 143.459 1.00 21.58  ? 395 TRP A NE1 1 
ATOM   2592 C CE2 . TRP A 1 387 ? 164.465 231.929 144.063 1.00 19.52  ? 395 TRP A CE2 1 
ATOM   2593 C CE3 . TRP A 1 387 ? 163.764 233.666 145.526 1.00 23.04  ? 395 TRP A CE3 1 
ATOM   2594 C CZ2 . TRP A 1 387 ? 163.214 231.388 144.036 1.00 22.26  ? 395 TRP A CZ2 1 
ATOM   2595 C CZ3 . TRP A 1 387 ? 162.503 233.108 145.507 1.00 26.01  ? 395 TRP A CZ3 1 
ATOM   2596 C CH2 . TRP A 1 387 ? 162.240 231.999 144.775 1.00 24.49  ? 395 TRP A CH2 1 
ATOM   2597 N N   . ILE A 1 388 ? 167.615 237.926 144.681 1.00 35.83  ? 396 ILE A N   1 
ATOM   2598 C CA  . ILE A 1 388 ? 168.421 239.048 145.170 1.00 37.98  ? 396 ILE A CA  1 
ATOM   2599 C C   . ILE A 1 388 ? 167.792 239.673 146.411 1.00 41.04  ? 396 ILE A C   1 
ATOM   2600 O O   . ILE A 1 388 ? 166.673 240.180 146.314 1.00 42.16  ? 396 ILE A O   1 
ATOM   2601 C CB  . ILE A 1 388 ? 168.544 240.127 144.065 1.00 39.45  ? 396 ILE A CB  1 
ATOM   2602 C CG1 . ILE A 1 388 ? 169.215 239.491 142.836 1.00 37.75  ? 396 ILE A CG1 1 
ATOM   2603 C CG2 . ILE A 1 388 ? 169.322 241.354 144.579 1.00 42.80  ? 396 ILE A CG2 1 
ATOM   2604 C CD1 . ILE A 1 388 ? 169.227 240.311 141.589 1.00 42.46  ? 396 ILE A CD1 1 
ATOM   2605 N N   . SER A 1 389 ? 168.517 239.669 147.574 1.00 39.98  ? 397 SER A N   1 
ATOM   2606 C CA  . SER A 1 389 ? 168.089 240.193 148.892 1.00 42.30  ? 397 SER A CA  1 
ATOM   2607 C C   . SER A 1 389 ? 166.560 240.115 149.142 1.00 43.36  ? 397 SER A C   1 
ATOM   2608 O O   . SER A 1 389 ? 166.012 239.044 149.452 1.00 40.25  ? 397 SER A O   1 
ATOM   2609 C CB  . SER A 1 389 ? 168.591 241.636 149.067 1.00 46.91  ? 397 SER A CB  1 
ATOM   2610 O OG  . SER A 1 389 ? 168.182 242.173 150.293 1.00 48.12  ? 397 SER A OG  1 
ATOM   2611 N N   . ASN A 1 402 ? 147.215 227.488 136.701 1.00 53.29  ? 399 ASN A N   1 
ATOM   2612 C CA  . ASN A 1 402 ? 147.758 226.225 137.192 1.00 54.47  ? 399 ASN A CA  1 
ATOM   2613 C C   . ASN A 1 402 ? 148.866 225.714 136.227 1.00 50.19  ? 399 ASN A C   1 
ATOM   2614 O O   . ASN A 1 402 ? 148.743 224.644 135.614 1.00 50.37  ? 399 ASN A O   1 
ATOM   2615 C CB  . ASN A 1 402 ? 146.606 225.196 137.421 1.00 62.70  ? 399 ASN A CB  1 
ATOM   2616 C CG  . ASN A 1 402 ? 147.009 223.874 138.237 1.00 60.16  ? 399 ASN A CG  1 
ATOM   2617 O OD1 . ASN A 1 402 ? 148.027 223.848 138.958 1.00 54.15  ? 399 ASN A OD1 1 
ATOM   2618 N ND2 . ASN A 1 402 ? 146.184 222.799 138.109 1.00 65.04  ? 399 ASN A ND2 1 
ATOM   2619 N N   . ASP A 1 403 ? 149.949 226.512 136.110 1.00 46.92  ? 412 ASP A N   1 
ATOM   2620 C CA  . ASP A 1 403 ? 151.143 226.266 135.290 1.00 39.25  ? 412 ASP A CA  1 
ATOM   2621 C C   . ASP A 1 403 ? 152.060 225.191 135.834 1.00 34.71  ? 412 ASP A C   1 
ATOM   2622 O O   . ASP A 1 403 ? 152.153 224.982 137.048 1.00 32.00  ? 412 ASP A O   1 
ATOM   2623 C CB  . ASP A 1 403 ? 151.987 227.517 135.181 1.00 40.17  ? 412 ASP A CB  1 
ATOM   2624 C CG  . ASP A 1 403 ? 151.425 228.612 134.319 1.00 45.62  ? 412 ASP A CG  1 
ATOM   2625 O OD1 . ASP A 1 403 ? 150.493 228.402 133.588 1.00 48.65  ? 412 ASP A OD1 1 
ATOM   2626 O OD2 . ASP A 1 403 ? 151.995 229.684 134.382 1.00 50.18  ? 412 ASP A OD2 1 
ATOM   2627 N N   . SER A 1 404 ? 152.810 224.581 134.934 1.00 31.08  ? 413 SER A N   1 
ATOM   2628 C CA  . SER A 1 404 ? 153.802 223.585 135.281 1.00 24.97  ? 413 SER A CA  1 
ATOM   2629 C C   . SER A 1 404 ? 155.025 223.733 134.421 1.00 22.41  ? 413 SER A C   1 
ATOM   2630 O O   . SER A 1 404 ? 154.988 224.327 133.342 1.00 23.87  ? 413 SER A O   1 
ATOM   2631 C CB  . SER A 1 404 ? 153.217 222.200 135.150 1.00 23.31  ? 413 SER A CB  1 
ATOM   2632 O OG  . SER A 1 404 ? 152.793 221.954 133.841 1.00 25.10  ? 413 SER A OG  1 
ATOM   2633 N N   . ILE A 1 405 ? 156.116 223.196 134.923 1.00 21.31  ? 414 ILE A N   1 
ATOM   2634 C CA  . ILE A 1 405 ? 157.391 223.199 134.258 1.00 19.84  ? 414 ILE A CA  1 
ATOM   2635 C C   . ILE A 1 405 ? 157.591 221.849 133.631 1.00 20.57  ? 414 ILE A C   1 
ATOM   2636 O O   . ILE A 1 405 ? 157.560 220.842 134.339 1.00 21.37  ? 414 ILE A O   1 
ATOM   2637 C CB  . ILE A 1 405 ? 158.512 223.418 135.287 1.00 18.68  ? 414 ILE A CB  1 
ATOM   2638 C CG1 . ILE A 1 405 ? 158.294 224.745 136.017 1.00 19.68  ? 414 ILE A CG1 1 
ATOM   2639 C CG2 . ILE A 1 405 ? 159.871 223.378 134.582 1.00 18.50  ? 414 ILE A CG2 1 
ATOM   2640 C CD1 . ILE A 1 405 ? 159.143 224.922 137.255 1.00 17.01  ? 414 ILE A CD1 1 
ATOM   2641 N N   . THR A 1 406 ? 157.783 221.811 132.316 1.00 20.53  ? 415 THR A N   1 
ATOM   2642 C CA  . THR A 1 406 ? 157.987 220.546 131.630 1.00 17.35  ? 415 THR A CA  1 
ATOM   2643 C C   . THR A 1 406 ? 159.467 220.343 131.393 1.00 17.45  ? 415 THR A C   1 
ATOM   2644 O O   . THR A 1 406 ? 160.144 221.201 130.827 1.00 17.94  ? 415 THR A O   1 
ATOM   2645 C CB  . THR A 1 406 ? 157.230 220.468 130.298 1.00 20.10  ? 415 THR A CB  1 
ATOM   2646 O OG1 . THR A 1 406 ? 155.824 220.587 130.526 1.00 22.31  ? 415 THR A OG1 1 
ATOM   2647 C CG2 . THR A 1 406 ? 157.493 219.158 129.611 1.00 21.41  ? 415 THR A CG2 1 
ATOM   2648 N N   . LEU A 1 407 ? 159.954 219.204 131.841 1.00 17.12  ? 416 LEU A N   1 
ATOM   2649 C CA  . LEU A 1 407 ? 161.340 218.805 131.749 1.00 15.95  ? 416 LEU A CA  1 
ATOM   2650 C C   . LEU A 1 407 ? 161.486 217.706 130.696 1.00 15.20  ? 416 LEU A C   1 
ATOM   2651 O O   . LEU A 1 407 ? 160.867 216.661 130.859 1.00 17.60  ? 416 LEU A O   1 
ATOM   2652 C CB  . LEU A 1 407 ? 161.756 218.254 133.113 1.00 15.11  ? 416 LEU A CB  1 
ATOM   2653 C CG  . LEU A 1 407 ? 161.454 219.178 134.328 1.00 13.77  ? 416 LEU A CG  1 
ATOM   2654 C CD1 . LEU A 1 407 ? 161.850 218.470 135.579 1.00 12.15  ? 416 LEU A CD1 1 
ATOM   2655 C CD2 . LEU A 1 407 ? 162.170 220.501 134.198 1.00 13.80  ? 416 LEU A CD2 1 
ATOM   2656 N N   . PRO A 1 408 ? 162.156 217.927 129.554 1.00 14.23  ? 417 PRO A N   1 
ATOM   2657 C CA  . PRO A 1 408 ? 162.374 216.944 128.504 1.00 15.17  ? 417 PRO A CA  1 
ATOM   2658 C C   . PRO A 1 408 ? 163.173 215.784 129.075 1.00 13.74  ? 417 PRO A C   1 
ATOM   2659 O O   . PRO A 1 408 ? 164.101 216.065 129.837 1.00 14.40  ? 417 PRO A O   1 
ATOM   2660 C CB  . PRO A 1 408 ? 163.209 217.729 127.498 1.00 16.60  ? 417 PRO A CB  1 
ATOM   2661 C CG  . PRO A 1 408 ? 162.895 219.157 127.769 1.00 14.49  ? 417 PRO A CG  1 
ATOM   2662 C CD  . PRO A 1 408 ? 162.681 219.244 129.246 1.00 14.34  ? 417 PRO A CD  1 
ATOM   2663 N N   . CYS A 1 409 ? 162.878 214.518 128.680 1.00 14.95  ? 418 CYS A N   1 
ATOM   2664 C CA  . CYS A 1 409 ? 163.593 213.321 129.163 1.00 12.04  ? 418 CYS A CA  1 
ATOM   2665 C C   . CYS A 1 409 ? 164.028 212.397 128.028 1.00 13.48  ? 418 CYS A C   1 
ATOM   2666 O O   . CYS A 1 409 ? 163.278 212.104 127.092 1.00 16.17  ? 418 CYS A O   1 
ATOM   2667 C CB  . CYS A 1 409 ? 162.705 212.514 130.158 1.00 10.94  ? 418 CYS A CB  1 
ATOM   2668 S SG  . CYS A 1 409 ? 162.072 213.468 131.580 1.00 16.76  ? 418 CYS A SG  1 
ATOM   2669 N N   . ARG A 1 410 ? 165.237 211.874 128.155 1.00 13.34  ? 419 ARG A N   1 
ATOM   2670 C CA  . ARG A 1 410 ? 165.750 210.885 127.236 1.00 11.12  ? 419 ARG A CA  1 
ATOM   2671 C C   . ARG A 1 410 ? 165.579 209.521 127.865 1.00 11.50  ? 419 ARG A C   1 
ATOM   2672 O O   . ARG A 1 410 ? 165.567 209.399 129.088 1.00 12.30  ? 419 ARG A O   1 
ATOM   2673 C CB  . ARG A 1 410 ? 167.200 211.134 126.933 1.00 13.14  ? 419 ARG A CB  1 
ATOM   2674 C CG  . ARG A 1 410 ? 167.469 212.420 126.224 1.00 17.01  ? 419 ARG A CG  1 
ATOM   2675 C CD  . ARG A 1 410 ? 168.913 212.616 125.971 1.00 21.39  ? 419 ARG A CD  1 
ATOM   2676 N NE  . ARG A 1 410 ? 169.178 213.867 125.320 1.00 30.11  ? 419 ARG A NE  1 
ATOM   2677 C CZ  . ARG A 1 410 ? 169.100 214.052 123.993 1.00 37.62  ? 419 ARG A CZ  1 
ATOM   2678 N NH1 . ARG A 1 410 ? 168.751 213.046 123.229 1.00 37.35  ? 419 ARG A NH1 1 
ATOM   2679 N NH2 . ARG A 1 410 ? 169.359 215.240 123.469 1.00 43.41  ? 419 ARG A NH2 1 
ATOM   2680 N N   . ILE A 1 411 ? 165.439 208.492 127.049 1.00 14.32  ? 420 ILE A N   1 
ATOM   2681 C CA  . ILE A 1 411 ? 165.295 207.132 127.561 1.00 12.77  ? 420 ILE A CA  1 
ATOM   2682 C C   . ILE A 1 411 ? 166.441 206.264 127.072 1.00 12.66  ? 420 ILE A C   1 
ATOM   2683 O O   . ILE A 1 411 ? 166.839 206.379 125.916 1.00 14.53  ? 420 ILE A O   1 
ATOM   2684 C CB  . ILE A 1 411 ? 163.948 206.511 127.114 1.00 14.01  ? 420 ILE A CB  1 
ATOM   2685 C CG1 . ILE A 1 411 ? 162.733 207.408 127.509 1.00 13.36  ? 420 ILE A CG1 1 
ATOM   2686 C CG2 . ILE A 1 411 ? 163.777 205.101 127.706 1.00 14.30  ? 420 ILE A CG2 1 
ATOM   2687 C CD1 . ILE A 1 411 ? 162.504 207.614 128.962 1.00 13.17  ? 420 ILE A CD1 1 
ATOM   2688 N N   . LYS A 1 412 ? 167.002 205.436 127.956 1.00 13.50  ? 421 LYS A N   1 
ATOM   2689 C CA  . LYS A 1 412 ? 168.069 204.508 127.553 1.00 13.56  ? 421 LYS A CA  1 
ATOM   2690 C C   . LYS A 1 412 ? 167.739 203.082 127.933 1.00 14.00  ? 421 LYS A C   1 
ATOM   2691 O O   . LYS A 1 412 ? 167.185 202.841 129.003 1.00 12.91  ? 421 LYS A O   1 
ATOM   2692 C CB  . LYS A 1 412 ? 169.388 204.805 128.251 1.00 14.39  ? 421 LYS A CB  1 
ATOM   2693 C CG  . LYS A 1 412 ? 170.017 206.087 127.928 1.00 14.53  ? 421 LYS A CG  1 
ATOM   2694 C CD  . LYS A 1 412 ? 171.279 206.301 128.744 1.00 14.86  ? 421 LYS A CD  1 
ATOM   2695 C CE  . LYS A 1 412 ? 172.470 205.575 128.198 1.00 19.59  ? 421 LYS A CE  1 
ATOM   2696 N NZ  . LYS A 1 412 ? 173.705 205.907 128.972 1.00 26.64  ? 421 LYS A NZ  1 
ATOM   2697 N N   . GLN A 1 413 ? 168.145 202.118 127.105 1.00 14.17  ? 422 GLN A N   1 
ATOM   2698 C CA  . GLN A 1 413 ? 168.000 200.723 127.471 1.00 12.54  ? 422 GLN A CA  1 
ATOM   2699 C C   . GLN A 1 413 ? 169.295 200.120 127.974 1.00 11.48  ? 422 GLN A C   1 
ATOM   2700 O O   . GLN A 1 413 ? 169.258 199.148 128.718 1.00 12.80  ? 422 GLN A O   1 
ATOM   2701 C CB  . GLN A 1 413 ? 167.447 199.910 126.334 1.00 13.13  ? 422 GLN A CB  1 
ATOM   2702 C CG  . GLN A 1 413 ? 166.074 200.293 125.970 1.00 13.11  ? 422 GLN A CG  1 
ATOM   2703 C CD  . GLN A 1 413 ? 165.555 199.511 124.854 1.00 13.42  ? 422 GLN A CD  1 
ATOM   2704 O OE1 . GLN A 1 413 ? 166.280 199.060 123.955 1.00 0.00   ? 422 GLN A OE1 1 
ATOM   2705 N NE2 . GLN A 1 413 ? 164.265 199.338 124.860 1.00 14.82  ? 422 GLN A NE2 1 
ATOM   2706 N N   . ILE A 1 414 ? 170.429 200.677 127.612 1.00 13.68  ? 423 ILE A N   1 
ATOM   2707 C CA  . ILE A 1 414 ? 171.729 200.090 128.045 1.00 14.07  ? 423 ILE A CA  1 
ATOM   2708 C C   . ILE A 1 414 ? 172.305 200.973 129.144 1.00 14.15  ? 423 ILE A C   1 
ATOM   2709 O O   . ILE A 1 414 ? 172.720 202.073 128.842 1.00 16.08  ? 423 ILE A O   1 
ATOM   2710 C CB  . ILE A 1 414 ? 172.726 199.807 126.893 1.00 14.71  ? 423 ILE A CB  1 
ATOM   2711 C CG1 . ILE A 1 414 ? 172.153 198.833 125.864 1.00 12.75  ? 423 ILE A CG1 1 
ATOM   2712 C CG2 . ILE A 1 414 ? 174.050 199.315 127.448 1.00 16.31  ? 423 ILE A CG2 1 
ATOM   2713 C CD1 . ILE A 1 414 ? 173.083 198.550 124.724 1.00 13.70  ? 423 ILE A CD1 1 
ATOM   2714 N N   . ILE A 1 415 ? 172.324 200.500 130.378 1.00 15.45  ? 424 ILE A N   1 
ATOM   2715 C CA  . ILE A 1 415 ? 172.767 201.356 131.468 1.00 16.74  ? 424 ILE A CA  1 
ATOM   2716 C C   . ILE A 1 415 ? 173.873 200.722 132.294 1.00 17.26  ? 424 ILE A C   1 
ATOM   2717 O O   . ILE A 1 415 ? 174.054 199.505 132.283 1.00 18.93  ? 424 ILE A O   1 
ATOM   2718 C CB  . ILE A 1 415 ? 171.610 201.714 132.411 1.00 17.75  ? 424 ILE A CB  1 
ATOM   2719 C CG1 . ILE A 1 415 ? 171.116 200.472 133.120 1.00 15.38  ? 424 ILE A CG1 1 
ATOM   2720 C CG2 . ILE A 1 415 ? 170.447 202.373 131.572 1.00 14.90  ? 424 ILE A CG2 1 
ATOM   2721 C CD1 . ILE A 1 415 ? 170.199 200.779 134.203 1.00 18.25  ? 424 ILE A CD1 1 
ATOM   2722 N N   . ASN A 1 416 ? 174.604 201.557 133.041 1.00 20.22  ? 425 ASN A N   1 
ATOM   2723 C CA  . ASN A 1 416 ? 175.695 201.079 133.940 1.00 22.33  ? 425 ASN A CA  1 
ATOM   2724 C C   . ASN A 1 416 ? 175.399 201.223 135.443 1.00 23.60  ? 425 ASN A C   1 
ATOM   2725 O O   . ASN A 1 416 ? 176.239 200.795 136.225 1.00 24.86  ? 425 ASN A O   1 
ATOM   2726 C CB  . ASN A 1 416 ? 177.003 201.789 133.627 1.00 23.90  ? 425 ASN A CB  1 
ATOM   2727 C CG  . ASN A 1 416 ? 177.417 201.657 132.178 1.00 23.82  ? 425 ASN A CG  1 
ATOM   2728 O OD1 . ASN A 1 416 ? 177.158 202.543 131.371 1.00 22.92  ? 425 ASN A OD1 1 
ATOM   2729 N ND2 . ASN A 1 416 ? 178.064 200.556 131.841 1.00 24.04  ? 425 ASN A ND2 1 
ATOM   2730 N N   . MET A 1 417 ? 174.258 201.739 135.856 1.00 23.78  ? 426 MET A N   1 
ATOM   2731 C CA  . MET A 1 417 ? 173.798 201.837 137.259 1.00 23.19  ? 426 MET A CA  1 
ATOM   2732 C C   . MET A 1 417 ? 174.716 202.421 138.296 1.00 25.11  ? 426 MET A C   1 
ATOM   2733 O O   . MET A 1 417 ? 174.438 203.465 138.887 1.00 24.11  ? 426 MET A O   1 
ATOM   2734 C CB  . MET A 1 417 ? 173.395 200.488 137.822 1.00 20.83  ? 426 MET A CB  1 
ATOM   2735 C CG  . MET A 1 417 ? 172.163 199.974 137.373 1.00 22.40  ? 426 MET A CG  1 
ATOM   2736 S SD  . MET A 1 417 ? 170.781 201.013 137.874 1.00 25.63  ? 426 MET A SD  1 
ATOM   2737 C CE  . MET A 1 417 ? 170.775 200.892 139.671 1.00 20.73  ? 426 MET A CE  1 
ATOM   2738 N N   . TRP A 1 418 ? 175.759 201.701 138.578 1.00 22.81  ? 427 TRP A N   1 
ATOM   2739 C CA  . TRP A 1 418 ? 176.679 202.088 139.606 1.00 21.76  ? 427 TRP A CA  1 
ATOM   2740 C C   . TRP A 1 418 ? 177.807 202.706 138.846 1.00 26.10  ? 427 TRP A C   1 
ATOM   2741 O O   . TRP A 1 418 ? 177.934 202.457 137.649 1.00 29.75  ? 427 TRP A O   1 
ATOM   2742 C CB  . TRP A 1 418 ? 177.067 200.886 140.438 1.00 20.87  ? 427 TRP A CB  1 
ATOM   2743 C CG  . TRP A 1 418 ? 175.841 200.165 140.913 1.00 20.04  ? 427 TRP A CG  1 
ATOM   2744 C CD1 . TRP A 1 418 ? 175.476 198.961 140.477 1.00 19.00  ? 427 TRP A CD1 1 
ATOM   2745 C CD2 . TRP A 1 418 ? 174.785 200.584 141.786 1.00 19.03  ? 427 TRP A CD2 1 
ATOM   2746 N NE1 . TRP A 1 418 ? 174.316 198.590 141.022 1.00 17.79  ? 427 TRP A NE1 1 
ATOM   2747 C CE2 . TRP A 1 418 ? 173.865 199.553 141.808 1.00 17.01  ? 427 TRP A CE2 1 
ATOM   2748 C CE3 . TRP A 1 418 ? 174.540 201.722 142.524 1.00 17.70  ? 427 TRP A CE3 1 
ATOM   2749 C CZ2 . TRP A 1 418 ? 172.732 199.617 142.529 1.00 17.05  ? 427 TRP A CZ2 1 
ATOM   2750 C CZ3 . TRP A 1 418 ? 173.386 201.780 143.249 1.00 17.17  ? 427 TRP A CZ3 1 
ATOM   2751 C CH2 . TRP A 1 418 ? 172.511 200.757 143.249 1.00 17.21  ? 427 TRP A CH2 1 
ATOM   2752 N N   . GLN A 1 419 ? 178.633 203.519 139.467 1.00 27.42  ? 428 GLN A N   1 
ATOM   2753 C CA  . GLN A 1 419 ? 179.708 204.112 138.682 1.00 30.33  ? 428 GLN A CA  1 
ATOM   2754 C C   . GLN A 1 419 ? 180.835 203.107 138.458 1.00 30.01  ? 428 GLN A C   1 
ATOM   2755 O O   . GLN A 1 419 ? 181.869 203.133 139.122 1.00 31.67  ? 428 GLN A O   1 
ATOM   2756 C CB  . GLN A 1 419 ? 180.248 205.356 139.373 1.00 33.43  ? 428 GLN A CB  1 
ATOM   2757 C CG  . GLN A 1 419 ? 179.249 206.493 139.506 1.00 33.84  ? 428 GLN A CG  1 
ATOM   2758 C CD  . GLN A 1 419 ? 179.872 207.681 140.191 1.00 36.90  ? 428 GLN A CD  1 
ATOM   2759 O OE1 . GLN A 1 419 ? 181.096 207.830 140.156 1.00 43.73  ? 428 GLN A OE1 1 
ATOM   2760 N NE2 . GLN A 1 419 ? 179.082 208.529 140.807 1.00 34.85  ? 428 GLN A NE2 1 
ATOM   2761 N N   . ARG A 1 420 ? 180.585 202.203 137.517 1.00 29.41  ? 429 ARG A N   1 
ATOM   2762 C CA  . ARG A 1 420 ? 181.443 201.089 137.168 1.00 32.30  ? 429 ARG A CA  1 
ATOM   2763 C C   . ARG A 1 420 ? 181.645 201.031 135.663 1.00 35.16  ? 429 ARG A C   1 
ATOM   2764 O O   . ARG A 1 420 ? 180.901 201.642 134.902 1.00 33.01  ? 429 ARG A O   1 
ATOM   2765 C CB  . ARG A 1 420 ? 180.861 199.781 137.657 1.00 28.57  ? 429 ARG A CB  1 
ATOM   2766 C CG  . ARG A 1 420 ? 180.696 199.700 139.149 1.00 26.69  ? 429 ARG A CG  1 
ATOM   2767 C CD  . ARG A 1 420 ? 180.379 198.328 139.636 1.00 23.98  ? 429 ARG A CD  1 
ATOM   2768 N NE  . ARG A 1 420 ? 179.118 197.816 139.130 1.00 23.27  ? 429 ARG A NE  1 
ATOM   2769 C CZ  . ARG A 1 420 ? 178.541 196.662 139.531 1.00 22.13  ? 429 ARG A CZ  1 
ATOM   2770 N NH1 . ARG A 1 420 ? 179.097 195.916 140.460 1.00 22.81  ? 429 ARG A NH1 1 
ATOM   2771 N NH2 . ARG A 1 420 ? 177.399 196.277 138.992 1.00 21.44  ? 429 ARG A NH2 1 
ATOM   2772 N N   . ILE A 1 421 ? 182.702 200.352 135.249 1.00 37.40  ? 430 ILE A N   1 
ATOM   2773 C CA  . ILE A 1 421 ? 183.056 200.208 133.838 1.00 40.65  ? 430 ILE A CA  1 
ATOM   2774 C C   . ILE A 1 421 ? 182.740 198.848 133.209 1.00 37.45  ? 430 ILE A C   1 
ATOM   2775 O O   . ILE A 1 421 ? 182.381 198.769 132.037 1.00 35.76  ? 430 ILE A O   1 
ATOM   2776 C CB  . ILE A 1 421 ? 184.549 200.536 133.644 1.00 42.46  ? 430 ILE A CB  1 
ATOM   2777 C CG1 . ILE A 1 421 ? 184.861 201.990 134.172 1.00 43.61  ? 430 ILE A CG1 1 
ATOM   2778 C CG2 . ILE A 1 421 ? 184.967 200.382 132.171 1.00 44.08  ? 430 ILE A CG2 1 
ATOM   2779 C CD1 . ILE A 1 421 ? 184.073 203.140 133.532 1.00 43.22  ? 430 ILE A CD1 1 
ATOM   2780 N N   . GLY A 1 422 ? 182.952 197.773 133.957 1.00 36.47  ? 431 GLY A N   1 
ATOM   2781 C CA  . GLY A 1 422 ? 182.902 196.413 133.423 1.00 35.00  ? 431 GLY A CA  1 
ATOM   2782 C C   . GLY A 1 422 ? 181.549 195.714 133.431 1.00 32.41  ? 431 GLY A C   1 
ATOM   2783 O O   . GLY A 1 422 ? 181.482 194.499 133.243 1.00 33.42  ? 431 GLY A O   1 
ATOM   2784 N N   . GLN A 1 423 ? 180.489 196.425 133.739 1.00 32.06  ? 432 GLN A N   1 
ATOM   2785 C CA  . GLN A 1 423 ? 179.173 195.824 133.777 1.00 28.21  ? 432 GLN A CA  1 
ATOM   2786 C C   . GLN A 1 423 ? 178.212 196.685 132.984 1.00 26.42  ? 432 GLN A C   1 
ATOM   2787 O O   . GLN A 1 423 ? 178.311 197.912 133.014 1.00 27.22  ? 432 GLN A O   1 
ATOM   2788 C CB  . GLN A 1 423 ? 178.706 195.701 135.225 1.00 29.55  ? 432 GLN A CB  1 
ATOM   2789 C CG  . GLN A 1 423 ? 179.539 194.758 136.123 1.00 29.59  ? 432 GLN A CG  1 
ATOM   2790 C CD  . GLN A 1 423 ? 180.859 195.372 136.608 1.00 31.00  ? 432 GLN A CD  1 
ATOM   2791 O OE1 . GLN A 1 423 ? 180.995 196.591 136.777 1.00 30.34  ? 432 GLN A OE1 1 
ATOM   2792 N NE2 . GLN A 1 423 ? 181.835 194.511 136.848 1.00 31.66  ? 432 GLN A NE2 1 
ATOM   2793 N N   . ALA A 1 424 ? 177.236 196.055 132.358 1.00 21.47  ? 433 ALA A N   1 
ATOM   2794 C CA  . ALA A 1 424 ? 176.198 196.798 131.642 1.00 17.67  ? 433 ALA A CA  1 
ATOM   2795 C C   . ALA A 1 424 ? 174.964 195.943 131.656 1.00 15.37  ? 433 ALA A C   1 
ATOM   2796 O O   . ALA A 1 424 ? 175.079 194.734 131.685 1.00 17.77  ? 433 ALA A O   1 
ATOM   2797 C CB  . ALA A 1 424 ? 176.599 197.053 130.261 1.00 19.85  ? 433 ALA A CB  1 
ATOM   2798 N N   . MET A 1 425 ? 173.837 196.591 131.678 1.00 14.87  ? 434 MET A N   1 
ATOM   2799 C CA  . MET A 1 425 ? 172.576 195.899 131.708 1.00 11.32  ? 434 MET A CA  1 
ATOM   2800 C C   . MET A 1 425 ? 171.661 196.384 130.624 1.00 11.03  ? 434 MET A C   1 
ATOM   2801 O O   . MET A 1 425 ? 171.590 197.577 130.345 1.00 12.99  ? 434 MET A O   1 
ATOM   2802 C CB  . MET A 1 425 ? 171.897 196.154 133.043 1.00 12.34  ? 434 MET A CB  1 
ATOM   2803 C CG  . MET A 1 425 ? 170.604 195.383 133.282 1.00 13.94  ? 434 MET A CG  1 
ATOM   2804 S SD  . MET A 1 425 ? 169.810 195.875 134.760 1.00 17.76  ? 434 MET A SD  1 
ATOM   2805 C CE  . MET A 1 425 ? 168.898 197.236 134.100 1.00 14.99  ? 434 MET A CE  1 
ATOM   2806 N N   . TYR A 1 426 ? 170.916 195.473 130.041 1.00 10.95  ? 435 TYR A N   1 
ATOM   2807 C CA  . TYR A 1 426 ? 169.900 195.838 129.091 1.00 9.48   ? 435 TYR A CA  1 
ATOM   2808 C C   . TYR A 1 426 ? 168.563 195.799 129.786 1.00 10.76  ? 435 TYR A C   1 
ATOM   2809 O O   . TYR A 1 426 ? 168.178 194.799 130.393 1.00 12.36  ? 435 TYR A O   1 
ATOM   2810 C CB  . TYR A 1 426 ? 169.896 194.919 127.878 1.00 9.05   ? 435 TYR A CB  1 
ATOM   2811 C CG  . TYR A 1 426 ? 168.851 195.223 126.891 1.00 8.51   ? 435 TYR A CG  1 
ATOM   2812 C CD1 . TYR A 1 426 ? 169.007 196.296 126.107 1.00 9.67   ? 435 TYR A CD1 1 
ATOM   2813 C CD2 . TYR A 1 426 ? 167.747 194.432 126.757 1.00 8.32   ? 435 TYR A CD2 1 
ATOM   2814 C CE1 . TYR A 1 426 ? 168.074 196.608 125.202 1.00 9.45   ? 435 TYR A CE1 1 
ATOM   2815 C CE2 . TYR A 1 426 ? 166.798 194.742 125.841 1.00 8.26   ? 435 TYR A CE2 1 
ATOM   2816 C CZ  . TYR A 1 426 ? 166.960 195.844 125.071 1.00 8.54   ? 435 TYR A CZ  1 
ATOM   2817 O OH  . TYR A 1 426 ? 166.018 196.217 124.153 1.00 10.11  ? 435 TYR A OH  1 
ATOM   2818 N N   . ALA A 1 427 ? 167.860 196.903 129.750 1.00 11.12  ? 436 ALA A N   1 
ATOM   2819 C CA  . ALA A 1 427 ? 166.561 196.962 130.344 1.00 9.93   ? 436 ALA A CA  1 
ATOM   2820 C C   . ALA A 1 427 ? 165.567 196.668 129.234 1.00 10.34  ? 436 ALA A C   1 
ATOM   2821 O O   . ALA A 1 427 ? 165.477 197.448 128.291 1.00 11.64  ? 436 ALA A O   1 
ATOM   2822 C CB  . ALA A 1 427 ? 166.324 198.315 130.968 1.00 11.72  ? 436 ALA A CB  1 
ATOM   2823 N N   . PRO A 1 428 ? 164.830 195.553 129.260 1.00 10.65  ? 437 PRO A N   1 
ATOM   2824 C CA  . PRO A 1 428 ? 163.942 195.194 128.202 1.00 10.82  ? 437 PRO A CA  1 
ATOM   2825 C C   . PRO A 1 428 ? 162.865 196.232 128.261 1.00 13.95  ? 437 PRO A C   1 
ATOM   2826 O O   . PRO A 1 428 ? 162.599 196.712 129.358 1.00 18.49  ? 437 PRO A O   1 
ATOM   2827 C CB  . PRO A 1 428 ? 163.483 193.801 128.609 1.00 12.36  ? 437 PRO A CB  1 
ATOM   2828 C CG  . PRO A 1 428 ? 163.630 193.772 130.100 1.00 13.90  ? 437 PRO A CG  1 
ATOM   2829 C CD  . PRO A 1 428 ? 164.806 194.654 130.404 1.00 12.40  ? 437 PRO A CD  1 
ATOM   2830 N N   . PRO A 1 429 ? 162.223 196.571 127.154 1.00 14.17  ? 438 PRO A N   1 
ATOM   2831 C CA  . PRO A 1 429 ? 161.158 197.527 127.063 1.00 15.28  ? 438 PRO A CA  1 
ATOM   2832 C C   . PRO A 1 429 ? 159.896 197.037 127.673 1.00 17.80  ? 438 PRO A C   1 
ATOM   2833 O O   . PRO A 1 429 ? 159.614 195.838 127.678 1.00 18.95  ? 438 PRO A O   1 
ATOM   2834 C CB  . PRO A 1 429 ? 161.002 197.702 125.576 1.00 15.52  ? 438 PRO A CB  1 
ATOM   2835 C CG  . PRO A 1 429 ? 161.473 196.436 125.017 1.00 13.76  ? 438 PRO A CG  1 
ATOM   2836 C CD  . PRO A 1 429 ? 162.574 195.967 125.909 1.00 13.23  ? 438 PRO A CD  1 
ATOM   2837 N N   . ILE A 1 430 ? 159.101 197.984 128.111 1.00 20.46  ? 439 ILE A N   1 
ATOM   2838 C CA  . ILE A 1 430 ? 157.807 197.710 128.671 1.00 20.96  ? 439 ILE A CA  1 
ATOM   2839 C C   . ILE A 1 430 ? 156.667 198.072 127.751 1.00 21.67  ? 439 ILE A C   1 
ATOM   2840 O O   . ILE A 1 430 ? 156.573 199.183 127.231 1.00 22.67  ? 439 ILE A O   1 
ATOM   2841 C CB  . ILE A 1 430 ? 157.685 198.412 130.005 1.00 21.61  ? 439 ILE A CB  1 
ATOM   2842 C CG1 . ILE A 1 430 ? 158.749 197.832 130.904 1.00 20.84  ? 439 ILE A CG1 1 
ATOM   2843 C CG2 . ILE A 1 430 ? 156.266 198.267 130.586 1.00 24.13  ? 439 ILE A CG2 1 
ATOM   2844 C CD1 . ILE A 1 430 ? 158.948 198.531 132.134 1.00 21.06  ? 439 ILE A CD1 1 
ATOM   2845 N N   . GLN A 1 431 ? 155.798 197.094 127.579 1.00 21.69  ? 440 GLN A N   1 
ATOM   2846 C CA  . GLN A 1 431 ? 154.613 197.160 126.749 1.00 21.78  ? 440 GLN A CA  1 
ATOM   2847 C C   . GLN A 1 431 ? 153.661 198.247 127.190 1.00 22.11  ? 440 GLN A C   1 
ATOM   2848 O O   . GLN A 1 431 ? 153.324 198.337 128.370 1.00 22.38  ? 440 GLN A O   1 
ATOM   2849 C CB  . GLN A 1 431 ? 153.903 195.801 126.822 1.00 22.22  ? 440 GLN A CB  1 
ATOM   2850 C CG  . GLN A 1 431 ? 152.588 195.675 126.062 1.00 23.19  ? 440 GLN A CG  1 
ATOM   2851 C CD  . GLN A 1 431 ? 152.769 195.735 124.587 1.00 22.83  ? 440 GLN A CD  1 
ATOM   2852 O OE1 . GLN A 1 431 ? 153.674 195.092 124.049 1.00 22.99  ? 440 GLN A OE1 1 
ATOM   2853 N NE2 . GLN A 1 431 ? 151.897 196.472 123.921 1.00 24.96  ? 440 GLN A NE2 1 
ATOM   2854 N N   . GLY A 1 432 ? 153.190 199.045 126.241 1.00 23.21  ? 441 GLY A N   1 
ATOM   2855 C CA  . GLY A 1 432 ? 152.231 200.088 126.576 1.00 22.96  ? 441 GLY A CA  1 
ATOM   2856 C C   . GLY A 1 432 ? 152.807 201.482 126.773 1.00 22.58  ? 441 GLY A C   1 
ATOM   2857 O O   . GLY A 1 432 ? 153.787 201.880 126.138 1.00 25.93  ? 441 GLY A O   1 
ATOM   2858 N N   . VAL A 1 433 ? 152.103 202.266 127.588 1.00 23.31  ? 442 VAL A N   1 
ATOM   2859 C CA  . VAL A 1 433 ? 152.385 203.677 127.841 1.00 22.77  ? 442 VAL A CA  1 
ATOM   2860 C C   . VAL A 1 433 ? 152.715 203.821 129.322 1.00 21.95  ? 442 VAL A C   1 
ATOM   2861 O O   . VAL A 1 433 ? 152.038 203.229 130.158 1.00 21.60  ? 442 VAL A O   1 
ATOM   2862 C CB  . VAL A 1 433 ? 151.175 204.555 127.473 1.00 23.46  ? 442 VAL A CB  1 
ATOM   2863 C CG1 . VAL A 1 433 ? 151.481 206.019 127.756 1.00 22.27  ? 442 VAL A CG1 1 
ATOM   2864 C CG2 . VAL A 1 433 ? 150.839 204.363 126.011 1.00 26.36  ? 442 VAL A CG2 1 
ATOM   2865 N N   . ILE A 1 434 ? 153.780 204.551 129.649 1.00 22.10  ? 443 ILE A N   1 
ATOM   2866 C CA  . ILE A 1 434 ? 154.191 204.677 131.056 1.00 20.97  ? 443 ILE A CA  1 
ATOM   2867 C C   . ILE A 1 434 ? 154.005 206.008 131.717 1.00 21.12  ? 443 ILE A C   1 
ATOM   2868 O O   . ILE A 1 434 ? 154.378 207.053 131.195 1.00 20.87  ? 443 ILE A O   1 
ATOM   2869 C CB  . ILE A 1 434 ? 155.640 204.218 131.279 1.00 20.99  ? 443 ILE A CB  1 
ATOM   2870 C CG1 . ILE A 1 434 ? 155.681 202.744 131.013 1.00 22.68  ? 443 ILE A CG1 1 
ATOM   2871 C CG2 . ILE A 1 434 ? 156.186 204.604 132.701 1.00 23.15  ? 443 ILE A CG2 1 
ATOM   2872 C CD1 . ILE A 1 434 ? 157.011 202.167 130.984 1.00 22.50  ? 443 ILE A CD1 1 
ATOM   2873 N N   . ARG A 1 435 ? 153.421 205.947 132.905 1.00 22.52  ? 444 ARG A N   1 
ATOM   2874 C CA  . ARG A 1 435 ? 153.230 207.099 133.761 1.00 21.73  ? 444 ARG A CA  1 
ATOM   2875 C C   . ARG A 1 435 ? 153.588 206.712 135.204 1.00 21.81  ? 444 ARG A C   1 
ATOM   2876 O O   . ARG A 1 435 ? 153.180 205.634 135.650 1.00 23.60  ? 444 ARG A O   1 
ATOM   2877 C CB  . ARG A 1 435 ? 151.793 207.569 133.687 1.00 25.36  ? 444 ARG A CB  1 
ATOM   2878 C CG  . ARG A 1 435 ? 151.470 208.793 134.507 1.00 28.10  ? 444 ARG A CG  1 
ATOM   2879 C CD  . ARG A 1 435 ? 150.081 209.200 134.316 1.00 35.41  ? 444 ARG A CD  1 
ATOM   2880 N NE  . ARG A 1 435 ? 149.751 210.387 135.084 1.00 39.76  ? 444 ARG A NE  1 
ATOM   2881 C CZ  . ARG A 1 435 ? 149.316 210.403 136.364 1.00 39.42  ? 444 ARG A CZ  1 
ATOM   2882 N NH1 . ARG A 1 435 ? 149.179 209.283 137.049 1.00 39.73  ? 444 ARG A NH1 1 
ATOM   2883 N NH2 . ARG A 1 435 ? 149.022 211.563 136.923 1.00 35.54  ? 444 ARG A NH2 1 
ATOM   2884 N N   . CYS A 1 436 ? 154.300 207.600 135.941 1.00 21.08  ? 445 CYS A N   1 
ATOM   2885 C CA  . CYS A 1 436 ? 154.643 207.427 137.358 1.00 20.27  ? 445 CYS A CA  1 
ATOM   2886 C C   . CYS A 1 436 ? 154.568 208.785 138.061 1.00 19.00  ? 445 CYS A C   1 
ATOM   2887 O O   . CYS A 1 436 ? 154.840 209.845 137.482 1.00 19.09  ? 445 CYS A O   1 
ATOM   2888 C CB  . CYS A 1 436 ? 156.053 206.765 137.569 1.00 20.77  ? 445 CYS A CB  1 
ATOM   2889 S SG  . CYS A 1 436 ? 157.528 207.730 137.008 1.00 23.01  ? 445 CYS A SG  1 
ATOM   2890 N N   . VAL A 1 437 ? 154.192 208.745 139.332 1.00 20.34  ? 446 VAL A N   1 
ATOM   2891 C CA  . VAL A 1 437 ? 154.123 209.938 140.162 1.00 19.25  ? 446 VAL A CA  1 
ATOM   2892 C C   . VAL A 1 437 ? 154.964 209.777 141.408 1.00 17.93  ? 446 VAL A C   1 
ATOM   2893 O O   . VAL A 1 437 ? 154.793 208.821 142.155 1.00 19.01  ? 446 VAL A O   1 
ATOM   2894 C CB  . VAL A 1 437 ? 152.666 210.246 140.543 1.00 19.94  ? 446 VAL A CB  1 
ATOM   2895 C CG1 . VAL A 1 437 ? 152.612 211.460 141.438 1.00 19.83  ? 446 VAL A CG1 1 
ATOM   2896 C CG2 . VAL A 1 437 ? 151.861 210.491 139.274 1.00 24.24  ? 446 VAL A CG2 1 
ATOM   2897 N N   . SER A 1 438 ? 155.817 210.748 141.670 1.00 17.79  ? 447 SER A N   1 
ATOM   2898 C CA  . SER A 1 438 ? 156.699 210.686 142.830 1.00 15.38  ? 447 SER A CA  1 
ATOM   2899 C C   . SER A 1 438 ? 156.846 212.034 143.532 1.00 15.21  ? 447 SER A C   1 
ATOM   2900 O O   . SER A 1 438 ? 156.480 213.073 142.976 1.00 17.14  ? 447 SER A O   1 
ATOM   2901 C CB  . SER A 1 438 ? 158.056 210.177 142.377 1.00 14.35  ? 447 SER A CB  1 
ATOM   2902 O OG  . SER A 1 438 ? 158.646 211.063 141.489 1.00 15.46  ? 447 SER A OG  1 
ATOM   2903 N N   . ASN A 1 439 ? 157.348 212.008 144.794 1.00 15.35  ? 448 ASN A N   1 
ATOM   2904 C CA  . ASN A 1 439 ? 157.603 213.192 145.620 1.00 11.76  ? 448 ASN A CA  1 
ATOM   2905 C C   . ASN A 1 439 ? 159.088 213.559 145.615 1.00 9.76   ? 448 ASN A C   1 
ATOM   2906 O O   . ASN A 1 439 ? 159.933 212.710 145.905 1.00 11.82  ? 448 ASN A O   1 
ATOM   2907 C CB  . ASN A 1 439 ? 157.161 212.956 147.075 1.00 15.01  ? 448 ASN A CB  1 
ATOM   2908 C CG  . ASN A 1 439 ? 155.642 212.953 147.332 1.00 19.43  ? 448 ASN A CG  1 
ATOM   2909 O OD1 . ASN A 1 439 ? 154.809 213.231 146.450 1.00 20.45  ? 448 ASN A OD1 1 
ATOM   2910 N ND2 . ASN A 1 439 ? 155.296 212.630 148.584 1.00 25.47  ? 448 ASN A ND2 1 
ATOM   2911 N N   . ILE A 1 440 ? 159.414 214.860 145.415 1.00 9.62   ? 449 ILE A N   1 
ATOM   2912 C CA  . ILE A 1 440 ? 160.774 215.398 145.560 1.00 8.36   ? 449 ILE A CA  1 
ATOM   2913 C C   . ILE A 1 440 ? 160.844 215.764 147.031 1.00 9.74   ? 449 ILE A C   1 
ATOM   2914 O O   . ILE A 1 440 ? 160.051 216.575 147.505 1.00 11.93  ? 449 ILE A O   1 
ATOM   2915 C CB  . ILE A 1 440 ? 161.001 216.658 144.710 1.00 7.78   ? 449 ILE A CB  1 
ATOM   2916 C CG1 . ILE A 1 440 ? 160.793 216.346 143.219 1.00 7.31   ? 449 ILE A CG1 1 
ATOM   2917 C CG2 . ILE A 1 440 ? 162.417 217.215 144.969 1.00 7.47   ? 449 ILE A CG2 1 
ATOM   2918 C CD1 . ILE A 1 440 ? 160.686 217.572 142.307 1.00 5.69   ? 449 ILE A CD1 1 
ATOM   2919 N N   . THR A 1 441 ? 161.740 215.114 147.759 1.00 9.73   ? 450 THR A N   1 
ATOM   2920 C CA  . THR A 1 441 ? 161.859 215.269 149.205 1.00 8.34   ? 450 THR A CA  1 
ATOM   2921 C C   . THR A 1 441 ? 163.193 215.873 149.609 1.00 8.59   ? 450 THR A C   1 
ATOM   2922 O O   . THR A 1 441 ? 163.527 215.991 150.789 1.00 10.83  ? 450 THR A O   1 
ATOM   2923 C CB  . THR A 1 441 ? 161.620 213.920 149.904 1.00 10.44  ? 450 THR A CB  1 
ATOM   2924 O OG1 . THR A 1 441 ? 162.578 212.954 149.446 1.00 11.77  ? 450 THR A OG1 1 
ATOM   2925 C CG2 . THR A 1 441 ? 160.226 213.418 149.567 1.00 10.69  ? 450 THR A CG2 1 
ATOM   2926 N N   . GLY A 1 442 ? 163.970 216.248 148.623 1.00 7.95   ? 451 GLY A N   1 
ATOM   2927 C CA  . GLY A 1 442 ? 165.273 216.828 148.848 1.00 8.08   ? 451 GLY A CA  1 
ATOM   2928 C C   . GLY A 1 442 ? 166.037 217.017 147.568 1.00 8.33   ? 451 GLY A C   1 
ATOM   2929 O O   . GLY A 1 442 ? 165.739 216.389 146.555 1.00 9.73   ? 451 GLY A O   1 
ATOM   2930 N N   . LEU A 1 443 ? 167.041 217.866 147.636 1.00 8.87   ? 452 LEU A N   1 
ATOM   2931 C CA  . LEU A 1 443 ? 167.881 218.215 146.500 1.00 8.89   ? 452 LEU A CA  1 
ATOM   2932 C C   . LEU A 1 443 ? 169.346 217.937 146.785 1.00 9.40   ? 452 LEU A C   1 
ATOM   2933 O O   . LEU A 1 443 ? 169.776 218.030 147.934 1.00 10.93  ? 452 LEU A O   1 
ATOM   2934 C CB  . LEU A 1 443 ? 167.762 219.722 146.240 1.00 8.85   ? 452 LEU A CB  1 
ATOM   2935 C CG  . LEU A 1 443 ? 166.346 220.294 146.140 1.00 8.87   ? 452 LEU A CG  1 
ATOM   2936 C CD1 . LEU A 1 443 ? 166.436 221.793 146.017 1.00 8.31   ? 452 LEU A CD1 1 
ATOM   2937 C CD2 . LEU A 1 443 ? 165.607 219.696 145.003 1.00 12.36  ? 452 LEU A CD2 1 
ATOM   2938 N N   . ILE A 1 444 ? 170.140 217.631 145.760 1.00 12.04  ? 453 ILE A N   1 
ATOM   2939 C CA  . ILE A 1 444 ? 171.582 217.615 145.989 1.00 11.62  ? 453 ILE A CA  1 
ATOM   2940 C C   . ILE A 1 444 ? 172.198 218.730 145.173 1.00 12.36  ? 453 ILE A C   1 
ATOM   2941 O O   . ILE A 1 444 ? 172.083 218.730 143.949 1.00 16.10  ? 453 ILE A O   1 
ATOM   2942 C CB  . ILE A 1 444 ? 172.249 216.285 145.637 1.00 13.51  ? 453 ILE A CB  1 
ATOM   2943 C CG1 . ILE A 1 444 ? 171.619 215.176 146.476 1.00 15.12  ? 453 ILE A CG1 1 
ATOM   2944 C CG2 . ILE A 1 444 ? 173.771 216.417 145.916 1.00 15.09  ? 453 ILE A CG2 1 
ATOM   2945 C CD1 . ILE A 1 444 ? 172.055 213.777 146.125 1.00 18.06  ? 453 ILE A CD1 1 
ATOM   2946 N N   . LEU A 1 445 ? 172.823 219.684 145.855 1.00 13.39  ? 454 LEU A N   1 
ATOM   2947 C CA  . LEU A 1 445 ? 173.427 220.860 145.227 1.00 13.02  ? 454 LEU A CA  1 
ATOM   2948 C C   . LEU A 1 445 ? 174.916 220.977 145.446 1.00 13.19  ? 454 LEU A C   1 
ATOM   2949 O O   . LEU A 1 445 ? 175.454 220.533 146.451 1.00 17.22  ? 454 LEU A O   1 
ATOM   2950 C CB  . LEU A 1 445 ? 172.807 222.151 145.764 1.00 12.91  ? 454 LEU A CB  1 
ATOM   2951 C CG  . LEU A 1 445 ? 171.317 222.351 145.604 1.00 10.72  ? 454 LEU A CG  1 
ATOM   2952 C CD1 . LEU A 1 445 ? 170.928 223.601 146.363 1.00 12.32  ? 454 LEU A CD1 1 
ATOM   2953 C CD2 . LEU A 1 445 ? 170.957 222.485 144.122 1.00 12.77  ? 454 LEU A CD2 1 
ATOM   2954 N N   . THR A 1 446 ? 175.597 221.629 144.535 1.00 16.36  ? 455 THR A N   1 
ATOM   2955 C CA  . THR A 1 446 ? 176.999 221.930 144.729 1.00 19.87  ? 455 THR A CA  1 
ATOM   2956 C C   . THR A 1 446 ? 177.103 223.428 144.596 1.00 20.38  ? 455 THR A C   1 
ATOM   2957 O O   . THR A 1 446 ? 176.224 224.060 144.017 1.00 20.34  ? 455 THR A O   1 
ATOM   2958 C CB  . THR A 1 446 ? 177.894 221.246 143.678 1.00 21.01  ? 455 THR A CB  1 
ATOM   2959 O OG1 . THR A 1 446 ? 177.675 221.821 142.386 1.00 21.09  ? 455 THR A OG1 1 
ATOM   2960 C CG2 . THR A 1 446 ? 177.495 219.794 143.602 1.00 20.39  ? 455 THR A CG2 1 
ATOM   2961 N N   . ARG A 1 447 ? 178.176 224.012 145.087 1.00 22.38  ? 456 ARG A N   1 
ATOM   2962 C CA  . ARG A 1 447 ? 178.351 225.448 144.966 1.00 23.04  ? 456 ARG A CA  1 
ATOM   2963 C C   . ARG A 1 447 ? 179.613 225.712 144.161 1.00 27.40  ? 456 ARG A C   1 
ATOM   2964 O O   . ARG A 1 447 ? 180.575 224.961 144.308 1.00 29.23  ? 456 ARG A O   1 
ATOM   2965 C CB  . ARG A 1 447 ? 178.432 226.065 146.353 1.00 23.70  ? 456 ARG A CB  1 
ATOM   2966 C CG  . ARG A 1 447 ? 178.598 227.563 146.402 1.00 24.73  ? 456 ARG A CG  1 
ATOM   2967 C CD  . ARG A 1 447 ? 178.450 228.080 147.761 1.00 24.15  ? 456 ARG A CD  1 
ATOM   2968 N NE  . ARG A 1 447 ? 179.419 227.529 148.658 1.00 24.63  ? 456 ARG A NE  1 
ATOM   2969 C CZ  . ARG A 1 447 ? 180.653 227.984 148.879 1.00 25.64  ? 456 ARG A CZ  1 
ATOM   2970 N NH1 . ARG A 1 447 ? 181.136 229.053 148.259 1.00 26.82  ? 456 ARG A NH1 1 
ATOM   2971 N NH2 . ARG A 1 447 ? 181.365 227.328 149.757 1.00 26.40  ? 456 ARG A NH2 1 
ATOM   2972 N N   . ASP A 1 448 ? 179.614 226.772 143.311 1.00 28.24  ? 457 ASP A N   1 
ATOM   2973 C CA  . ASP A 1 448 ? 180.774 227.202 142.513 1.00 30.26  ? 457 ASP A CA  1 
ATOM   2974 C C   . ASP A 1 448 ? 181.892 227.674 143.448 1.00 33.02  ? 457 ASP A C   1 
ATOM   2975 O O   . ASP A 1 448 ? 183.086 227.537 143.158 1.00 35.24  ? 457 ASP A O   1 
ATOM   2976 C CB  . ASP A 1 448 ? 180.410 228.325 141.483 1.00 30.70  ? 457 ASP A CB  1 
ATOM   2977 C CG  . ASP A 1 448 ? 179.514 227.880 140.243 1.00 30.84  ? 457 ASP A CG  1 
ATOM   2978 O OD1 . ASP A 1 448 ? 179.267 226.722 140.055 1.00 29.61  ? 457 ASP A OD1 1 
ATOM   2979 O OD2 . ASP A 1 448 ? 179.148 228.753 139.500 1.00 30.18  ? 457 ASP A OD2 1 
ATOM   2980 N N   . THR A 1 455 ? 180.333 239.688 145.156 1.00 51.60  ? 464 THR A N   1 
ATOM   2981 C CA  . THR A 1 455 ? 179.490 238.701 145.801 1.00 47.43  ? 464 THR A CA  1 
ATOM   2982 C C   . THR A 1 455 ? 178.784 237.858 144.701 1.00 47.31  ? 464 THR A C   1 
ATOM   2983 O O   . THR A 1 455 ? 179.198 237.913 143.535 1.00 45.27  ? 464 THR A O   1 
ATOM   2984 C CB  . THR A 1 455 ? 178.502 239.389 146.839 1.00 50.65  ? 464 THR A CB  1 
ATOM   2985 O OG1 . THR A 1 455 ? 177.880 238.353 147.630 1.00 46.51  ? 464 THR A OG1 1 
ATOM   2986 C CG2 . THR A 1 455 ? 177.344 240.289 146.155 1.00 48.41  ? 464 THR A CG2 1 
ATOM   2987 N N   . THR A 1 456 ? 177.727 237.111 145.106 1.00 42.00  ? 465 THR A N   1 
ATOM   2988 C CA  . THR A 1 456 ? 176.834 236.188 144.367 1.00 38.61  ? 465 THR A CA  1 
ATOM   2989 C C   . THR A 1 456 ? 177.316 234.754 144.420 1.00 35.53  ? 465 THR A C   1 
ATOM   2990 O O   . THR A 1 456 ? 178.374 234.406 143.893 1.00 34.42  ? 465 THR A O   1 
ATOM   2991 C CB  . THR A 1 456 ? 176.599 236.540 142.867 1.00 39.20  ? 465 THR A CB  1 
ATOM   2992 O OG1 . THR A 1 456 ? 176.054 237.853 142.763 1.00 41.13  ? 465 THR A OG1 1 
ATOM   2993 C CG2 . THR A 1 456 ? 175.582 235.543 142.265 1.00 38.08  ? 465 THR A CG2 1 
ATOM   2994 N N   . GLU A 1 457 ? 176.526 233.915 145.075 1.00 32.72  ? 466 GLU A N   1 
ATOM   2995 C CA  . GLU A 1 457 ? 176.844 232.500 145.167 1.00 29.95  ? 466 GLU A CA  1 
ATOM   2996 C C   . GLU A 1 457 ? 176.000 231.775 144.136 1.00 27.15  ? 466 GLU A C   1 
ATOM   2997 O O   . GLU A 1 457 ? 174.828 232.110 143.954 1.00 26.48  ? 466 GLU A O   1 
ATOM   2998 C CB  . GLU A 1 457 ? 176.560 231.943 146.562 1.00 26.99  ? 466 GLU A CB  1 
ATOM   2999 C CG  . GLU A 1 457 ? 177.410 232.505 147.709 1.00 26.93  ? 466 GLU A CG  1 
ATOM   3000 C CD  . GLU A 1 457 ? 178.850 231.989 147.747 1.00 27.37  ? 466 GLU A CD  1 
ATOM   3001 O OE1 . GLU A 1 457 ? 179.248 231.251 146.865 1.00 27.54  ? 466 GLU A OE1 1 
ATOM   3002 O OE2 . GLU A 1 457 ? 179.545 232.330 148.675 1.00 28.02  ? 466 GLU A OE2 1 
ATOM   3003 N N   . THR A 1 458 ? 176.579 230.785 143.475 1.00 26.97  ? 467 THR A N   1 
ATOM   3004 C CA  . THR A 1 458 ? 175.838 230.004 142.490 1.00 24.67  ? 467 THR A CA  1 
ATOM   3005 C C   . THR A 1 458 ? 175.812 228.545 142.872 1.00 21.34  ? 467 THR A C   1 
ATOM   3006 O O   . THR A 1 458 ? 176.848 227.942 143.180 1.00 24.17  ? 467 THR A O   1 
ATOM   3007 C CB  . THR A 1 458 ? 176.387 230.174 141.056 1.00 27.07  ? 467 THR A CB  1 
ATOM   3008 O OG1 . THR A 1 458 ? 176.296 231.552 140.680 1.00 29.10  ? 467 THR A OG1 1 
ATOM   3009 C CG2 . THR A 1 458 ? 175.553 229.339 140.069 1.00 25.43  ? 467 THR A CG2 1 
ATOM   3010 N N   . PHE A 1 459 ? 174.606 227.993 142.842 1.00 21.66  ? 468 PHE A N   1 
ATOM   3011 C CA  . PHE A 1 459 ? 174.343 226.614 143.186 1.00 18.84  ? 468 PHE A CA  1 
ATOM   3012 C C   . PHE A 1 459 ? 173.852 225.848 141.973 1.00 17.96  ? 468 PHE A C   1 
ATOM   3013 O O   . PHE A 1 459 ? 173.024 226.347 141.206 1.00 20.25  ? 468 PHE A O   1 
ATOM   3014 C CB  . PHE A 1 459 ? 173.300 226.568 144.292 1.00 18.36  ? 468 PHE A CB  1 
ATOM   3015 C CG  . PHE A 1 459 ? 173.777 227.213 145.538 1.00 18.81  ? 468 PHE A CG  1 
ATOM   3016 C CD1 . PHE A 1 459 ? 173.590 228.560 145.720 1.00 20.55  ? 468 PHE A CD1 1 
ATOM   3017 C CD2 . PHE A 1 459 ? 174.424 226.506 146.511 1.00 17.89  ? 468 PHE A CD2 1 
ATOM   3018 C CE1 . PHE A 1 459 ? 174.047 229.192 146.839 1.00 19.32  ? 468 PHE A CE1 1 
ATOM   3019 C CE2 . PHE A 1 459 ? 174.873 227.144 147.633 1.00 17.97  ? 468 PHE A CE2 1 
ATOM   3020 C CZ  . PHE A 1 459 ? 174.687 228.490 147.787 1.00 17.62  ? 468 PHE A CZ  1 
ATOM   3021 N N   . ARG A 1 460 ? 174.345 224.634 141.815 1.00 18.23  ? 469 ARG A N   1 
ATOM   3022 C CA  . ARG A 1 460 ? 173.976 223.799 140.684 1.00 16.54  ? 469 ARG A CA  1 
ATOM   3023 C C   . ARG A 1 460 ? 173.626 222.414 141.186 1.00 15.20  ? 469 ARG A C   1 
ATOM   3024 O O   . ARG A 1 460 ? 174.092 222.024 142.240 1.00 16.63  ? 469 ARG A O   1 
ATOM   3025 C CB  . ARG A 1 460 ? 175.141 223.686 139.725 1.00 18.88  ? 469 ARG A CB  1 
ATOM   3026 C CG  . ARG A 1 460 ? 175.581 224.972 139.143 1.00 20.03  ? 469 ARG A CG  1 
ATOM   3027 C CD  . ARG A 1 460 ? 176.734 224.819 138.287 1.00 23.61  ? 469 ARG A CD  1 
ATOM   3028 N NE  . ARG A 1 460 ? 177.288 226.090 137.972 1.00 25.94  ? 469 ARG A NE  1 
ATOM   3029 C CZ  . ARG A 1 460 ? 177.014 226.878 136.917 1.00 25.71  ? 469 ARG A CZ  1 
ATOM   3030 N NH1 . ARG A 1 460 ? 176.163 226.531 135.959 1.00 24.08  ? 469 ARG A NH1 1 
ATOM   3031 N NH2 . ARG A 1 460 ? 177.632 228.047 136.866 1.00 27.43  ? 469 ARG A NH2 1 
ATOM   3032 N N   . PRO A 1 461 ? 172.788 221.649 140.517 1.00 14.21  ? 470 PRO A N   1 
ATOM   3033 C CA  . PRO A 1 461 ? 172.507 220.274 140.843 1.00 12.46  ? 470 PRO A CA  1 
ATOM   3034 C C   . PRO A 1 461 ? 173.734 219.369 140.777 1.00 13.68  ? 470 PRO A C   1 
ATOM   3035 O O   . PRO A 1 461 ? 174.550 219.504 139.867 1.00 17.58  ? 470 PRO A O   1 
ATOM   3036 C CB  . PRO A 1 461 ? 171.514 219.925 139.770 1.00 12.67  ? 470 PRO A CB  1 
ATOM   3037 C CG  . PRO A 1 461 ? 170.921 221.201 139.360 1.00 13.06  ? 470 PRO A CG  1 
ATOM   3038 C CD  . PRO A 1 461 ? 171.981 222.188 139.448 1.00 15.64  ? 470 PRO A CD  1 
ATOM   3039 N N   . GLY A 1 462 ? 173.810 218.417 141.704 1.00 13.74  ? 471 GLY A N   1 
ATOM   3040 C CA  . GLY A 1 462 ? 174.860 217.396 141.781 1.00 15.48  ? 471 GLY A CA  1 
ATOM   3041 C C   . GLY A 1 462 ? 174.209 216.021 141.957 1.00 16.91  ? 471 GLY A C   1 
ATOM   3042 O O   . GLY A 1 462 ? 173.241 215.702 141.285 1.00 17.11  ? 471 GLY A O   1 
ATOM   3043 N N   . GLY A 1 463 ? 174.741 215.182 142.848 1.00 21.68  ? 472 GLY A N   1 
ATOM   3044 C CA  . GLY A 1 463 ? 174.111 213.874 143.109 1.00 22.78  ? 472 GLY A CA  1 
ATOM   3045 C C   . GLY A 1 463 ? 174.578 212.622 142.360 1.00 24.71  ? 472 GLY A C   1 
ATOM   3046 O O   . GLY A 1 463 ? 173.961 211.574 142.495 1.00 23.70  ? 472 GLY A O   1 
ATOM   3047 N N   . GLY A 1 464 ? 175.679 212.668 141.626 1.00 25.94  ? 473 GLY A N   1 
ATOM   3048 C CA  . GLY A 1 464 ? 176.125 211.464 140.911 1.00 28.45  ? 473 GLY A CA  1 
ATOM   3049 C C   . GLY A 1 464 ? 176.469 210.231 141.791 1.00 28.72  ? 473 GLY A C   1 
ATOM   3050 O O   . GLY A 1 464 ? 176.360 209.095 141.316 1.00 28.29  ? 473 GLY A O   1 
ATOM   3051 N N   . ASP A 1 465 ? 176.966 210.448 143.026 1.00 29.38  ? 474 ASP A N   1 
ATOM   3052 C CA  . ASP A 1 465 ? 177.353 209.381 143.975 1.00 24.73  ? 474 ASP A CA  1 
ATOM   3053 C C   . ASP A 1 465 ? 176.196 208.955 144.876 1.00 21.39  ? 474 ASP A C   1 
ATOM   3054 O O   . ASP A 1 465 ? 175.719 209.749 145.690 1.00 23.45  ? 474 ASP A O   1 
ATOM   3055 C CB  . ASP A 1 465 ? 178.535 209.772 144.857 1.00 24.34  ? 474 ASP A CB  1 
ATOM   3056 C CG  . ASP A 1 465 ? 178.978 208.583 145.739 1.00 25.82  ? 474 ASP A CG  1 
ATOM   3057 O OD1 . ASP A 1 465 ? 178.285 207.581 145.694 1.00 24.62  ? 474 ASP A OD1 1 
ATOM   3058 O OD2 . ASP A 1 465 ? 179.971 208.666 146.434 1.00 28.49  ? 474 ASP A OD2 1 
ATOM   3059 N N   . MET A 1 466 ? 175.747 207.713 144.737 1.00 21.71  ? 475 MET A N   1 
ATOM   3060 C CA  . MET A 1 466 ? 174.566 207.197 145.427 1.00 18.77  ? 475 MET A CA  1 
ATOM   3061 C C   . MET A 1 466 ? 174.712 207.177 146.934 1.00 16.31  ? 475 MET A C   1 
ATOM   3062 O O   . MET A 1 466 ? 173.714 207.157 147.652 1.00 19.53  ? 475 MET A O   1 
ATOM   3063 C CB  . MET A 1 466 ? 174.195 205.813 144.927 1.00 19.00  ? 475 MET A CB  1 
ATOM   3064 C CG  . MET A 1 466 ? 173.784 205.763 143.461 1.00 20.74  ? 475 MET A CG  1 
ATOM   3065 S SD  . MET A 1 466 ? 172.428 206.830 143.045 1.00 17.70  ? 475 MET A SD  1 
ATOM   3066 C CE  . MET A 1 466 ? 173.237 208.207 142.233 1.00 21.12  ? 475 MET A CE  1 
ATOM   3067 N N   . ARG A 1 467 ? 175.932 207.221 147.445 1.00 19.90  ? 476 ARG A N   1 
ATOM   3068 C CA  . ARG A 1 467 ? 176.063 207.218 148.891 1.00 17.52  ? 476 ARG A CA  1 
ATOM   3069 C C   . ARG A 1 467 ? 175.364 208.420 149.504 1.00 16.05  ? 476 ARG A C   1 
ATOM   3070 O O   . ARG A 1 467 ? 174.876 208.315 150.624 1.00 18.00  ? 476 ARG A O   1 
ATOM   3071 C CB  . ARG A 1 467 ? 177.507 207.188 149.340 1.00 20.70  ? 476 ARG A CB  1 
ATOM   3072 C CG  . ARG A 1 467 ? 178.189 205.872 149.116 1.00 22.73  ? 476 ARG A CG  1 
ATOM   3073 C CD  . ARG A 1 467 ? 179.583 205.862 149.588 1.00 27.05  ? 476 ARG A CD  1 
ATOM   3074 N NE  . ARG A 1 467 ? 180.440 206.690 148.751 1.00 35.13  ? 476 ARG A NE  1 
ATOM   3075 C CZ  . ARG A 1 467 ? 181.742 206.928 148.949 1.00 39.05  ? 476 ARG A CZ  1 
ATOM   3076 N NH1 . ARG A 1 467 ? 182.406 206.422 149.980 1.00 44.13  ? 476 ARG A NH1 1 
ATOM   3077 N NH2 . ARG A 1 467 ? 182.340 207.701 148.065 1.00 43.94  ? 476 ARG A NH2 1 
ATOM   3078 N N   . ASP A 1 468 ? 175.232 209.534 148.766 1.00 17.98  ? 477 ASP A N   1 
ATOM   3079 C CA  . ASP A 1 468 ? 174.554 210.710 149.288 1.00 15.49  ? 477 ASP A CA  1 
ATOM   3080 C C   . ASP A 1 468 ? 173.067 210.471 149.450 1.00 14.41  ? 477 ASP A C   1 
ATOM   3081 O O   . ASP A 1 468 ? 172.413 211.112 150.276 1.00 17.47  ? 477 ASP A O   1 
ATOM   3082 C CB  . ASP A 1 468 ? 174.748 211.919 148.384 1.00 17.81  ? 477 ASP A CB  1 
ATOM   3083 C CG  . ASP A 1 468 ? 176.132 212.596 148.451 1.00 21.61  ? 477 ASP A CG  1 
ATOM   3084 O OD1 . ASP A 1 468 ? 176.893 212.351 149.368 1.00 20.29  ? 477 ASP A OD1 1 
ATOM   3085 O OD2 . ASP A 1 468 ? 176.413 213.375 147.566 1.00 25.73  ? 477 ASP A OD2 1 
ATOM   3086 N N   . ASN A 1 469 ? 172.500 209.547 148.682 1.00 15.54  ? 478 ASN A N   1 
ATOM   3087 C CA  . ASN A 1 469 ? 171.085 209.319 148.780 1.00 14.02  ? 478 ASN A CA  1 
ATOM   3088 C C   . ASN A 1 469 ? 170.798 208.590 150.049 1.00 14.53  ? 478 ASN A C   1 
ATOM   3089 O O   . ASN A 1 469 ? 169.730 208.736 150.642 1.00 15.45  ? 478 ASN A O   1 
ATOM   3090 C CB  . ASN A 1 469 ? 170.596 208.457 147.656 1.00 15.75  ? 478 ASN A CB  1 
ATOM   3091 C CG  . ASN A 1 469 ? 170.674 209.095 146.393 1.00 15.70  ? 478 ASN A CG  1 
ATOM   3092 O OD1 . ASN A 1 469 ? 171.025 210.260 146.277 1.00 16.77  ? 478 ASN A OD1 1 
ATOM   3093 N ND2 . ASN A 1 469 ? 170.323 208.388 145.396 1.00 15.75  ? 478 ASN A ND2 1 
ATOM   3094 N N   . TRP A 1 470 ? 171.738 207.746 150.439 1.00 15.47  ? 479 TRP A N   1 
ATOM   3095 C CA  . TRP A 1 470 ? 171.560 206.946 151.623 1.00 12.84  ? 479 TRP A CA  1 
ATOM   3096 C C   . TRP A 1 470 ? 171.934 207.707 152.873 1.00 12.72  ? 479 TRP A C   1 
ATOM   3097 O O   . TRP A 1 470 ? 171.278 207.538 153.902 1.00 15.00  ? 479 TRP A O   1 
ATOM   3098 C CB  . TRP A 1 470 ? 172.260 205.634 151.363 1.00 14.90  ? 479 TRP A CB  1 
ATOM   3099 C CG  . TRP A 1 470 ? 171.532 204.967 150.160 1.00 17.07  ? 479 TRP A CG  1 
ATOM   3100 C CD1 . TRP A 1 470 ? 170.191 205.109 149.835 1.00 17.99  ? 479 TRP A CD1 1 
ATOM   3101 C CD2 . TRP A 1 470 ? 172.070 204.174 149.122 1.00 14.81  ? 479 TRP A CD2 1 
ATOM   3102 N NE1 . TRP A 1 470 ? 169.910 204.465 148.704 1.00 16.01  ? 479 TRP A NE1 1 
ATOM   3103 C CE2 . TRP A 1 470 ? 171.006 203.887 148.238 1.00 16.46  ? 479 TRP A CE2 1 
ATOM   3104 C CE3 . TRP A 1 470 ? 173.311 203.704 148.843 1.00 14.69  ? 479 TRP A CE3 1 
ATOM   3105 C CZ2 . TRP A 1 470 ? 171.176 203.151 147.130 1.00 18.07  ? 479 TRP A CZ2 1 
ATOM   3106 C CZ3 . TRP A 1 470 ? 173.464 202.961 147.702 1.00 17.25  ? 479 TRP A CZ3 1 
ATOM   3107 C CH2 . TRP A 1 470 ? 172.432 202.692 146.881 1.00 20.57  ? 479 TRP A CH2 1 
ATOM   3108 N N   . ARG A 1 471 ? 172.846 208.674 152.757 1.00 13.96  ? 480 ARG A N   1 
ATOM   3109 C CA  . ARG A 1 471 ? 173.179 209.513 153.896 1.00 11.60  ? 480 ARG A CA  1 
ATOM   3110 C C   . ARG A 1 471 ? 171.951 210.271 154.340 1.00 11.93  ? 480 ARG A C   1 
ATOM   3111 O O   . ARG A 1 471 ? 171.703 210.418 155.536 1.00 15.55  ? 480 ARG A O   1 
ATOM   3112 C CB  . ARG A 1 471 ? 174.271 210.509 153.591 1.00 13.12  ? 480 ARG A CB  1 
ATOM   3113 C CG  . ARG A 1 471 ? 175.591 209.941 153.456 1.00 14.38  ? 480 ARG A CG  1 
ATOM   3114 C CD  . ARG A 1 471 ? 176.626 210.914 153.392 1.00 14.55  ? 480 ARG A CD  1 
ATOM   3115 N NE  . ARG A 1 471 ? 177.904 210.249 153.238 1.00 16.18  ? 480 ARG A NE  1 
ATOM   3116 C CZ  . ARG A 1 471 ? 178.600 210.104 152.095 1.00 17.86  ? 480 ARG A CZ  1 
ATOM   3117 N NH1 . ARG A 1 471 ? 178.203 210.615 150.951 1.00 20.23  ? 480 ARG A NH1 1 
ATOM   3118 N NH2 . ARG A 1 471 ? 179.729 209.433 152.116 1.00 24.43  ? 480 ARG A NH2 1 
ATOM   3119 N N   . SER A 1 472 ? 171.127 210.670 153.387 1.00 13.15  ? 481 SER A N   1 
ATOM   3120 C CA  . SER A 1 472 ? 169.920 211.420 153.663 1.00 13.14  ? 481 SER A CA  1 
ATOM   3121 C C   . SER A 1 472 ? 168.881 210.684 154.506 1.00 13.63  ? 481 SER A C   1 
ATOM   3122 O O   . SER A 1 472 ? 167.967 211.323 155.026 1.00 15.13  ? 481 SER A O   1 
ATOM   3123 C CB  . SER A 1 472 ? 169.279 211.834 152.368 1.00 14.44  ? 481 SER A CB  1 
ATOM   3124 O OG  . SER A 1 472 ? 170.078 212.744 151.685 1.00 16.24  ? 481 SER A OG  1 
ATOM   3125 N N   . GLU A 1 473 ? 168.960 209.357 154.605 1.00 14.20  ? 482 GLU A N   1 
ATOM   3126 C CA  . GLU A 1 473 ? 168.019 208.609 155.439 1.00 13.26  ? 482 GLU A CA  1 
ATOM   3127 C C   . GLU A 1 473 ? 168.701 208.101 156.711 1.00 11.99  ? 482 GLU A C   1 
ATOM   3128 O O   . GLU A 1 473 ? 168.090 208.037 157.777 1.00 12.76  ? 482 GLU A O   1 
ATOM   3129 C CB  . GLU A 1 473 ? 167.386 207.462 154.667 1.00 15.06  ? 482 GLU A CB  1 
ATOM   3130 C CG  . GLU A 1 473 ? 166.514 207.905 153.486 1.00 16.07  ? 482 GLU A CG  1 
ATOM   3131 C CD  . GLU A 1 473 ? 165.182 208.582 153.878 1.00 18.15  ? 482 GLU A CD  1 
ATOM   3132 O OE1 . GLU A 1 473 ? 164.426 208.076 154.713 1.00 18.72  ? 482 GLU A OE1 1 
ATOM   3133 O OE2 . GLU A 1 473 ? 164.917 209.624 153.311 1.00 18.39  ? 482 GLU A OE2 1 
ATOM   3134 N N   . LEU A 1 474 ? 169.983 207.767 156.606 1.00 12.60  ? 483 LEU A N   1 
ATOM   3135 C CA  . LEU A 1 474 ? 170.737 207.210 157.713 1.00 10.50  ? 483 LEU A CA  1 
ATOM   3136 C C   . LEU A 1 474 ? 171.403 208.220 158.634 1.00 10.31  ? 483 LEU A C   1 
ATOM   3137 O O   . LEU A 1 474 ? 171.931 207.841 159.673 1.00 12.09  ? 483 LEU A O   1 
ATOM   3138 C CB  . LEU A 1 474 ? 171.796 206.258 157.166 1.00 11.21  ? 483 LEU A CB  1 
ATOM   3139 C CG  . LEU A 1 474 ? 171.293 204.966 156.494 1.00 10.75  ? 483 LEU A CG  1 
ATOM   3140 C CD1 . LEU A 1 474 ? 172.433 204.283 155.822 1.00 11.78  ? 483 LEU A CD1 1 
ATOM   3141 C CD2 . LEU A 1 474 ? 170.738 204.026 157.556 1.00 9.82   ? 483 LEU A CD2 1 
ATOM   3142 N N   . TYR A 1 475 ? 171.333 209.504 158.324 1.00 11.37  ? 484 TYR A N   1 
ATOM   3143 C CA  . TYR A 1 475 ? 171.978 210.541 159.128 1.00 10.61  ? 484 TYR A CA  1 
ATOM   3144 C C   . TYR A 1 475 ? 171.576 210.579 160.595 1.00 10.73  ? 484 TYR A C   1 
ATOM   3145 O O   . TYR A 1 475 ? 172.322 211.085 161.428 1.00 11.79  ? 484 TYR A O   1 
ATOM   3146 C CB  . TYR A 1 475 ? 171.682 211.915 158.553 1.00 10.82  ? 484 TYR A CB  1 
ATOM   3147 C CG  . TYR A 1 475 ? 170.322 212.405 158.813 1.00 10.96  ? 484 TYR A CG  1 
ATOM   3148 C CD1 . TYR A 1 475 ? 169.316 212.044 157.995 1.00 11.20  ? 484 TYR A CD1 1 
ATOM   3149 C CD2 . TYR A 1 475 ? 170.074 213.208 159.899 1.00 12.40  ? 484 TYR A CD2 1 
ATOM   3150 C CE1 . TYR A 1 475 ? 168.055 212.466 158.237 1.00 10.70  ? 484 TYR A CE1 1 
ATOM   3151 C CE2 . TYR A 1 475 ? 168.805 213.638 160.144 1.00 12.15  ? 484 TYR A CE2 1 
ATOM   3152 C CZ  . TYR A 1 475 ? 167.792 213.258 159.303 1.00 10.86  ? 484 TYR A CZ  1 
ATOM   3153 O OH  . TYR A 1 475 ? 166.515 213.693 159.524 1.00 14.66  ? 484 TYR A OH  1 
ATOM   3154 N N   . LYS A 1 476 ? 170.395 210.094 160.930 1.00 10.32  ? 485 LYS A N   1 
ATOM   3155 C CA  . LYS A 1 476 ? 169.928 210.141 162.302 1.00 8.85   ? 485 LYS A CA  1 
ATOM   3156 C C   . LYS A 1 476 ? 170.309 208.923 163.121 1.00 7.99   ? 485 LYS A C   1 
ATOM   3157 O O   . LYS A 1 476 ? 170.003 208.854 164.308 1.00 9.54   ? 485 LYS A O   1 
ATOM   3158 C CB  . LYS A 1 476 ? 168.434 210.400 162.334 1.00 9.42   ? 485 LYS A CB  1 
ATOM   3159 C CG  . LYS A 1 476 ? 167.556 209.318 161.815 1.00 9.28   ? 485 LYS A CG  1 
ATOM   3160 C CD  . LYS A 1 476 ? 166.133 209.809 161.837 1.00 10.80  ? 485 LYS A CD  1 
ATOM   3161 C CE  . LYS A 1 476 ? 165.165 208.807 161.286 1.00 14.73  ? 485 LYS A CE  1 
ATOM   3162 N NZ  . LYS A 1 476 ? 163.774 209.361 161.247 1.00 19.60  ? 485 LYS A NZ  1 
ATOM   3163 N N   . TYR A 1 477 ? 170.951 207.932 162.511 1.00 9.30   ? 486 TYR A N   1 
ATOM   3164 C CA  . TYR A 1 477 ? 171.283 206.729 163.258 1.00 7.68   ? 486 TYR A CA  1 
ATOM   3165 C C   . TYR A 1 477 ? 172.769 206.579 163.531 1.00 7.94   ? 486 TYR A C   1 
ATOM   3166 O O   . TYR A 1 477 ? 173.611 206.914 162.704 1.00 10.21  ? 486 TYR A O   1 
ATOM   3167 C CB  . TYR A 1 477 ? 170.826 205.498 162.517 1.00 8.65   ? 486 TYR A CB  1 
ATOM   3168 C CG  . TYR A 1 477 ? 169.382 205.387 162.330 1.00 8.13   ? 486 TYR A CG  1 
ATOM   3169 C CD1 . TYR A 1 477 ? 168.574 204.975 163.342 1.00 8.09   ? 486 TYR A CD1 1 
ATOM   3170 C CD2 . TYR A 1 477 ? 168.868 205.703 161.131 1.00 8.73   ? 486 TYR A CD2 1 
ATOM   3171 C CE1 . TYR A 1 477 ? 167.246 204.863 163.135 1.00 9.39   ? 486 TYR A CE1 1 
ATOM   3172 C CE2 . TYR A 1 477 ? 167.548 205.600 160.915 1.00 9.68   ? 486 TYR A CE2 1 
ATOM   3173 C CZ  . TYR A 1 477 ? 166.731 205.174 161.924 1.00 10.48  ? 486 TYR A CZ  1 
ATOM   3174 O OH  . TYR A 1 477 ? 165.398 205.049 161.695 1.00 13.43  ? 486 TYR A OH  1 
ATOM   3175 N N   . LYS A 1 478 ? 173.091 205.998 164.678 1.00 7.59   ? 487 LYS A N   1 
ATOM   3176 C CA  . LYS A 1 478 ? 174.471 205.702 165.047 1.00 6.58   ? 487 LYS A CA  1 
ATOM   3177 C C   . LYS A 1 478 ? 174.615 204.301 165.626 1.00 7.05   ? 487 LYS A C   1 
ATOM   3178 O O   . LYS A 1 478 ? 173.773 203.855 166.389 1.00 9.54   ? 487 LYS A O   1 
ATOM   3179 C CB  . LYS A 1 478 ? 174.930 206.725 166.082 1.00 7.07   ? 487 LYS A CB  1 
ATOM   3180 C CG  . LYS A 1 478 ? 176.334 206.623 166.483 1.00 8.59   ? 487 LYS A CG  1 
ATOM   3181 C CD  . LYS A 1 478 ? 176.719 207.655 167.500 1.00 9.16   ? 487 LYS A CD  1 
ATOM   3182 C CE  . LYS A 1 478 ? 178.212 207.669 167.601 1.00 16.34  ? 487 LYS A CE  1 
ATOM   3183 N NZ  . LYS A 1 478 ? 178.727 208.536 168.673 1.00 18.36  ? 487 LYS A NZ  1 
ATOM   3184 N N   . VAL A 1 479 ? 175.703 203.607 165.334 1.00 8.42   ? 488 VAL A N   1 
ATOM   3185 C CA  . VAL A 1 479 ? 175.909 202.293 165.950 1.00 7.81   ? 488 VAL A CA  1 
ATOM   3186 C C   . VAL A 1 479 ? 176.960 202.339 167.037 1.00 8.40   ? 488 VAL A C   1 
ATOM   3187 O O   . VAL A 1 479 ? 178.060 202.863 166.824 1.00 9.63   ? 488 VAL A O   1 
ATOM   3188 C CB  . VAL A 1 479 ? 176.307 201.237 164.905 1.00 7.87   ? 488 VAL A CB  1 
ATOM   3189 C CG1 . VAL A 1 479 ? 176.580 199.887 165.567 1.00 8.76   ? 488 VAL A CG1 1 
ATOM   3190 C CG2 . VAL A 1 479 ? 175.200 201.092 163.925 1.00 9.13   ? 488 VAL A CG2 1 
ATOM   3191 N N   . VAL A 1 480 ? 176.600 201.803 168.203 1.00 9.03   ? 489 VAL A N   1 
ATOM   3192 C CA  . VAL A 1 480 ? 177.517 201.755 169.324 1.00 8.48   ? 489 VAL A CA  1 
ATOM   3193 C C   . VAL A 1 480 ? 177.619 200.336 169.862 1.00 7.61   ? 489 VAL A C   1 
ATOM   3194 O O   . VAL A 1 480 ? 176.704 199.532 169.688 1.00 9.57   ? 489 VAL A O   1 
ATOM   3195 C CB  . VAL A 1 480 ? 177.042 202.711 170.437 1.00 7.30   ? 489 VAL A CB  1 
ATOM   3196 C CG1 . VAL A 1 480 ? 176.977 204.127 169.903 1.00 8.37   ? 489 VAL A CG1 1 
ATOM   3197 C CG2 . VAL A 1 480 ? 175.679 202.283 170.996 1.00 6.58   ? 489 VAL A CG2 1 
ATOM   3198 N N   . LYS A 1 481 ? 178.721 200.043 170.536 1.00 8.34   ? 490 LYS A N   1 
ATOM   3199 C CA  . LYS A 1 481 ? 178.968 198.765 171.178 1.00 7.91   ? 490 LYS A CA  1 
ATOM   3200 C C   . LYS A 1 481 ? 178.725 198.896 172.652 1.00 7.36   ? 490 LYS A C   1 
ATOM   3201 O O   . LYS A 1 481 ? 179.109 199.890 173.263 1.00 7.77   ? 490 LYS A O   1 
ATOM   3202 C CB  . LYS A 1 481 ? 180.384 198.288 170.914 1.00 9.24   ? 490 LYS A CB  1 
ATOM   3203 C CG  . LYS A 1 481 ? 180.703 196.946 171.486 1.00 10.83  ? 490 LYS A CG  1 
ATOM   3204 C CD  . LYS A 1 481 ? 182.075 196.489 171.104 1.00 12.27  ? 490 LYS A CD  1 
ATOM   3205 C CE  . LYS A 1 481 ? 182.349 195.160 171.729 1.00 17.92  ? 490 LYS A CE  1 
ATOM   3206 N NZ  . LYS A 1 481 ? 183.715 194.632 171.405 1.00 23.06  ? 490 LYS A NZ  1 
ATOM   3207 N N   . ILE A 1 482 ? 178.112 197.898 173.239 1.00 8.83   ? 491 ILE A N   1 
ATOM   3208 C CA  . ILE A 1 482 ? 177.810 197.937 174.655 1.00 7.91   ? 491 ILE A CA  1 
ATOM   3209 C C   . ILE A 1 482 ? 178.986 197.400 175.439 1.00 8.10   ? 491 ILE A C   1 
ATOM   3210 O O   . ILE A 1 482 ? 179.532 196.342 175.123 1.00 10.14  ? 491 ILE A O   1 
ATOM   3211 C CB  . ILE A 1 482 ? 176.547 197.125 174.944 1.00 8.77   ? 491 ILE A CB  1 
ATOM   3212 C CG1 . ILE A 1 482 ? 175.396 197.619 174.026 1.00 8.16   ? 491 ILE A CG1 1 
ATOM   3213 C CG2 . ILE A 1 482 ? 176.160 197.225 176.426 1.00 7.39   ? 491 ILE A CG2 1 
ATOM   3214 C CD1 . ILE A 1 482 ? 175.011 199.069 174.121 1.00 7.16   ? 491 ILE A CD1 1 
ATOM   3215 N N   . GLU A 1 483 ? 179.370 198.135 176.469 1.00 8.51   ? 492 GLU A N   1 
ATOM   3216 C CA  . GLU A 1 483 ? 180.491 197.801 177.325 1.00 7.72   ? 492 GLU A CA  1 
ATOM   3217 C C   . GLU A 1 483 ? 180.010 197.645 178.773 1.00 7.31   ? 492 GLU A C   1 
ATOM   3218 O O   . GLU A 1 483 ? 180.202 198.546 179.580 1.00 7.16   ? 492 GLU A O   1 
ATOM   3219 C CB  . GLU A 1 483 ? 181.526 198.917 177.237 1.00 8.62   ? 492 GLU A CB  1 
ATOM   3220 C CG  . GLU A 1 483 ? 182.208 199.065 175.874 1.00 14.30  ? 492 GLU A CG  1 
ATOM   3221 C CD  . GLU A 1 483 ? 183.195 197.954 175.564 1.00 13.72  ? 492 GLU A CD  1 
ATOM   3222 O OE1 . GLU A 1 483 ? 183.481 197.186 176.451 1.00 0.00   ? 492 GLU A OE1 1 
ATOM   3223 O OE2 . GLU A 1 483 ? 183.684 197.896 174.456 1.00 14.90  ? 492 GLU A OE2 1 
ATOM   3224 N N   . PRO A 1 484 ? 179.431 196.484 179.140 1.00 7.79   ? 493 PRO A N   1 
ATOM   3225 C CA  . PRO A 1 484 ? 178.726 196.205 180.373 1.00 6.53   ? 493 PRO A CA  1 
ATOM   3226 C C   . PRO A 1 484 ? 179.573 196.064 181.620 1.00 6.16   ? 493 PRO A C   1 
ATOM   3227 O O   . PRO A 1 484 ? 179.026 195.969 182.712 1.00 6.93   ? 493 PRO A O   1 
ATOM   3228 C CB  . PRO A 1 484 ? 178.063 194.874 180.053 1.00 6.93   ? 493 PRO A CB  1 
ATOM   3229 C CG  . PRO A 1 484 ? 178.976 194.234 179.078 1.00 7.38   ? 493 PRO A CG  1 
ATOM   3230 C CD  . PRO A 1 484 ? 179.526 195.321 178.266 1.00 8.20   ? 493 PRO A CD  1 
ATOM   3231 N N   . LEU A 1 485 ? 180.875 195.956 181.484 1.00 7.86   ? 494 LEU A N   1 
ATOM   3232 C CA  . LEU A 1 485 ? 181.701 195.729 182.654 1.00 6.68   ? 494 LEU A CA  1 
ATOM   3233 C C   . LEU A 1 485 ? 182.385 197.003 183.103 1.00 7.59   ? 494 LEU A C   1 
ATOM   3234 O O   . LEU A 1 485 ? 182.999 197.699 182.295 1.00 9.58   ? 494 LEU A O   1 
ATOM   3235 C CB  . LEU A 1 485 ? 182.727 194.636 182.311 1.00 8.75   ? 494 LEU A CB  1 
ATOM   3236 C CG  . LEU A 1 485 ? 183.726 194.189 183.387 1.00 7.21   ? 494 LEU A CG  1 
ATOM   3237 C CD1 . LEU A 1 485 ? 183.013 193.514 184.515 1.00 7.87   ? 494 LEU A CD1 1 
ATOM   3238 C CD2 . LEU A 1 485 ? 184.692 193.208 182.769 1.00 7.94   ? 494 LEU A CD2 1 
ATOM   3239 N N   . GLY A 1 486 ? 182.353 197.281 184.399 1.00 7.84   ? 495 GLY A N   1 
ATOM   3240 C CA  . GLY A 1 486 ? 183.044 198.453 184.906 1.00 11.37  ? 495 GLY A CA  1 
ATOM   3241 C C   . GLY A 1 486 ? 183.255 198.406 186.404 1.00 9.93   ? 495 GLY A C   1 
ATOM   3242 O O   . GLY A 1 486 ? 182.760 197.517 187.088 1.00 7.88   ? 495 GLY A O   1 
ATOM   3243 N N   . VAL A 1 487 ? 184.022 199.363 186.911 1.00 9.67   ? 496 VAL A N   1 
ATOM   3244 C CA  . VAL A 1 487 ? 184.350 199.416 188.329 1.00 7.51   ? 496 VAL A CA  1 
ATOM   3245 C C   . VAL A 1 487 ? 184.102 200.794 188.901 1.00 5.32   ? 496 VAL A C   1 
ATOM   3246 O O   . VAL A 1 487 ? 184.119 201.757 188.142 1.00 7.00   ? 496 VAL A O   1 
ATOM   3247 C CB  . VAL A 1 487 ? 185.839 199.043 188.529 1.00 10.44  ? 496 VAL A CB  1 
ATOM   3248 C CG1 . VAL A 1 487 ? 186.110 197.632 188.060 1.00 7.43   ? 496 VAL A CG1 1 
ATOM   3249 C CG2 . VAL A 1 487 ? 186.732 199.999 187.755 1.00 6.44   ? 496 VAL A CG2 1 
ATOM   3250 N N   . ALA A 1 488 ? 183.905 200.870 190.217 1.00 4.71   ? 497 ALA A N   1 
ATOM   3251 C CA  . ALA A 1 488 ? 183.732 202.129 190.940 1.00 3.32   ? 497 ALA A CA  1 
ATOM   3252 C C   . ALA A 1 488 ? 184.021 201.911 192.430 1.00 3.14   ? 497 ALA A C   1 
ATOM   3253 O O   . ALA A 1 488 ? 183.905 200.783 192.894 1.00 3.52   ? 497 ALA A O   1 
ATOM   3254 C CB  . ALA A 1 488 ? 182.318 202.633 190.716 1.00 3.37   ? 497 ALA A CB  1 
ATOM   3255 N N   . PRO A 1 489 ? 184.460 202.920 193.206 1.00 2.70   ? 498 PRO A N   1 
ATOM   3256 C CA  . PRO A 1 489 ? 184.674 202.828 194.637 1.00 2.22   ? 498 PRO A CA  1 
ATOM   3257 C C   . PRO A 1 489 ? 183.422 202.748 195.473 1.00 2.62   ? 498 PRO A C   1 
ATOM   3258 O O   . PRO A 1 489 ? 182.495 203.533 195.259 1.00 5.96   ? 498 PRO A O   1 
ATOM   3259 C CB  . PRO A 1 489 ? 185.366 204.124 194.937 1.00 1.85   ? 498 PRO A CB  1 
ATOM   3260 C CG  . PRO A 1 489 ? 184.928 205.049 193.877 1.00 2.20   ? 498 PRO A CG  1 
ATOM   3261 C CD  . PRO A 1 489 ? 184.738 204.217 192.659 1.00 2.36   ? 498 PRO A CD  1 
ATOM   3262 N N   . THR A 1 490 ? 183.429 201.883 196.471 1.00 2.42   ? 499 THR A N   1 
ATOM   3263 C CA  . THR A 1 490 ? 182.347 201.766 197.443 1.00 2.02   ? 499 THR A CA  1 
ATOM   3264 C C   . THR A 1 490 ? 182.946 201.525 198.809 1.00 1.17   ? 499 THR A C   1 
ATOM   3265 O O   . THR A 1 490 ? 184.145 201.300 198.937 1.00 1.98   ? 499 THR A O   1 
ATOM   3266 C CB  . THR A 1 490 ? 181.394 200.622 197.147 1.00 2.07   ? 499 THR A CB  1 
ATOM   3267 O OG1 . THR A 1 490 ? 182.059 199.424 197.440 1.00 1.09   ? 499 THR A OG1 1 
ATOM   3268 C CG2 . THR A 1 490 ? 180.988 200.635 195.679 1.00 3.76   ? 499 THR A CG2 1 
ATOM   3269 N N   . ARG A 1 491 ? 182.116 201.496 199.840 1.00 2.04   ? 500 ARG A N   1 
ATOM   3270 C CA  . ARG A 1 491 ? 182.581 201.171 201.201 1.00 1.13   ? 500 ARG A CA  1 
ATOM   3271 C C   . ARG A 1 491 ? 182.559 199.655 201.551 1.00 0.57   ? 500 ARG A C   1 
ATOM   3272 O O   . ARG A 1 491 ? 182.767 199.306 202.711 1.00 2.69   ? 500 ARG A O   1 
ATOM   3273 C CB  . ARG A 1 491 ? 181.724 201.859 202.245 1.00 1.13   ? 500 ARG A CB  1 
ATOM   3274 C CG  . ARG A 1 491 ? 181.667 203.331 202.226 1.00 0.45   ? 500 ARG A CG  1 
ATOM   3275 C CD  . ARG A 1 491 ? 182.887 203.921 202.762 1.00 3.60   ? 500 ARG A CD  1 
ATOM   3276 N NE  . ARG A 1 491 ? 182.872 205.375 202.713 1.00 0.06   ? 500 ARG A NE  1 
ATOM   3277 C CZ  . ARG A 1 491 ? 183.948 206.169 202.934 1.00 0.00   ? 500 ARG A CZ  1 
ATOM   3278 N NH1 . ARG A 1 491 ? 185.118 205.638 203.198 1.00 0.03   ? 500 ARG A NH1 1 
ATOM   3279 N NH2 . ARG A 1 491 ? 183.829 207.488 202.878 1.00 0.00   ? 500 ARG A NH2 1 
ATOM   3280 N N   . CYS A 1 492 ? 182.239 198.790 200.562 1.00 1.74   ? 501 CYS A N   1 
ATOM   3281 C CA  . CYS A 1 492 ? 182.085 197.344 200.653 1.00 0.91   ? 501 CYS A CA  1 
ATOM   3282 C C   . CYS A 1 492 ? 183.401 196.625 200.376 1.00 2.30   ? 501 CYS A C   1 
ATOM   3283 O O   . CYS A 1 492 ? 184.005 196.791 199.323 1.00 3.49   ? 501 CYS A O   1 
ATOM   3284 C CB  . CYS A 1 492 ? 181.034 196.882 199.610 1.00 0.97   ? 501 CYS A CB  1 
ATOM   3285 S SG  . CYS A 1 492 ? 180.733 195.119 199.550 1.00 9.38   ? 501 CYS A SG  1 
ATOM   3286 N N   . LYS A 1 493 ? 183.817 195.759 201.295 1.00 2.37   ? 502 LYS A N   1 
ATOM   3287 C CA  . LYS A 1 493 ? 185.027 194.996 201.003 1.00 2.44   ? 502 LYS A CA  1 
ATOM   3288 C C   . LYS A 1 493 ? 184.740 193.524 201.194 1.00 2.91   ? 502 LYS A C   1 
ATOM   3289 O O   . LYS A 1 493 ? 183.927 193.162 202.037 1.00 3.50   ? 502 LYS A O   1 
ATOM   3290 C CB  . LYS A 1 493 ? 186.216 195.393 201.866 1.00 4.16   ? 502 LYS A CB  1 
ATOM   3291 C CG  . LYS A 1 493 ? 186.123 195.079 203.305 1.00 4.88   ? 502 LYS A CG  1 
ATOM   3292 C CD  . LYS A 1 493 ? 187.380 195.519 203.995 1.00 5.75   ? 502 LYS A CD  1 
ATOM   3293 C CE  . LYS A 1 493 ? 187.395 195.106 205.444 1.00 27.89  ? 502 LYS A CE  1 
ATOM   3294 N NZ  . LYS A 1 493 ? 188.648 195.529 206.129 1.00 27.08  ? 502 LYS A NZ  1 
ATOM   3295 N N   . ARG A 1 494 ? 185.460 192.668 200.454 1.00 5.12   ? 503 ARG A N   1 
ATOM   3296 C CA  . ARG A 1 494 ? 185.359 191.213 200.515 1.00 3.92   ? 503 ARG A CA  1 
ATOM   3297 C C   . ARG A 1 494 ? 185.920 190.707 201.851 1.00 5.83   ? 503 ARG A C   1 
ATOM   3298 O O   . ARG A 1 494 ? 185.564 189.623 202.330 1.00 8.28   ? 503 ARG A O   1 
ATOM   3299 C CB  . ARG A 1 494 ? 186.117 190.593 199.329 1.00 4.21   ? 503 ARG A CB  1 
ATOM   3300 C CG  . ARG A 1 494 ? 185.984 189.045 199.107 1.00 3.92   ? 503 ARG A CG  1 
ATOM   3301 C CD  . ARG A 1 494 ? 186.809 188.521 197.942 1.00 3.60   ? 503 ARG A CD  1 
ATOM   3302 N NE  . ARG A 1 494 ? 186.370 188.998 196.567 1.00 4.55   ? 503 ARG A NE  1 
ATOM   3303 C CZ  . ARG A 1 494 ? 186.971 188.650 195.358 1.00 3.38   ? 503 ARG A CZ  1 
ATOM   3304 N NH1 . ARG A 1 494 ? 188.004 187.859 195.319 1.00 6.46   ? 503 ARG A NH1 1 
ATOM   3305 N NH2 . ARG A 1 494 ? 186.513 189.106 194.232 1.00 3.24   ? 503 ARG A NH2 1 
ATOM   3306 N N   . LEU B 2 9   ? 162.366 201.828 181.738 1.00 25.35  ? 518 LEU B N   1 
ATOM   3307 C CA  . LEU B 2 9   ? 162.589 200.511 182.353 1.00 27.02  ? 518 LEU B CA  1 
ATOM   3308 C C   . LEU B 2 9   ? 163.186 199.445 181.389 1.00 23.49  ? 518 LEU B C   1 
ATOM   3309 O O   . LEU B 2 9   ? 163.399 198.297 181.808 1.00 21.79  ? 518 LEU B O   1 
ATOM   3310 C CB  . LEU B 2 9   ? 161.249 199.953 182.972 1.00 29.99  ? 518 LEU B CB  1 
ATOM   3311 C CG  . LEU B 2 9   ? 160.555 200.762 184.211 1.00 38.25  ? 518 LEU B CG  1 
ATOM   3312 C CD1 . LEU B 2 9   ? 159.170 200.083 184.570 1.00 44.36  ? 518 LEU B CD1 1 
ATOM   3313 C CD2 . LEU B 2 9   ? 161.509 200.768 185.479 1.00 39.54  ? 518 LEU B CD2 1 
ATOM   3314 N N   . GLY B 2 10  ? 163.444 199.804 180.111 1.00 16.49  ? 519 GLY B N   1 
ATOM   3315 C CA  . GLY B 2 10  ? 164.011 198.914 179.092 1.00 13.25  ? 519 GLY B CA  1 
ATOM   3316 C C   . GLY B 2 10  ? 165.516 199.050 178.988 1.00 11.74  ? 519 GLY B C   1 
ATOM   3317 O O   . GLY B 2 10  ? 166.147 199.759 179.778 1.00 13.05  ? 519 GLY B O   1 
ATOM   3318 N N   . PHE B 2 11  ? 166.074 198.398 177.985 1.00 11.31  ? 520 PHE B N   1 
ATOM   3319 C CA  . PHE B 2 11  ? 167.498 198.395 177.736 1.00 9.68   ? 520 PHE B CA  1 
ATOM   3320 C C   . PHE B 2 11  ? 168.056 199.784 177.541 1.00 9.45   ? 520 PHE B C   1 
ATOM   3321 O O   . PHE B 2 11  ? 167.606 200.527 176.678 1.00 11.66  ? 520 PHE B O   1 
ATOM   3322 C CB  . PHE B 2 11  ? 167.714 197.536 176.508 1.00 10.06  ? 520 PHE B CB  1 
ATOM   3323 C CG  . PHE B 2 11  ? 169.059 197.384 176.079 1.00 10.64  ? 520 PHE B CG  1 
ATOM   3324 C CD1 . PHE B 2 11  ? 169.954 196.726 176.843 1.00 10.39  ? 520 PHE B CD1 1 
ATOM   3325 C CD2 . PHE B 2 11  ? 169.443 197.868 174.865 1.00 10.27  ? 520 PHE B CD2 1 
ATOM   3326 C CE1 . PHE B 2 11  ? 171.225 196.561 176.413 1.00 9.23   ? 520 PHE B CE1 1 
ATOM   3327 C CE2 . PHE B 2 11  ? 170.701 197.698 174.437 1.00 9.30   ? 520 PHE B CE2 1 
ATOM   3328 C CZ  . PHE B 2 11  ? 171.586 197.044 175.217 1.00 9.89   ? 520 PHE B CZ  1 
ATOM   3329 N N   . LEU B 2 12  ? 169.075 200.106 178.345 1.00 9.40   ? 521 LEU B N   1 
ATOM   3330 C CA  . LEU B 2 12  ? 169.780 201.382 178.393 1.00 7.78   ? 521 LEU B CA  1 
ATOM   3331 C C   . LEU B 2 12  ? 168.899 202.544 178.821 1.00 8.49   ? 521 LEU B C   1 
ATOM   3332 O O   . LEU B 2 12  ? 169.325 203.694 178.775 1.00 9.37   ? 521 LEU B O   1 
ATOM   3333 C CB  . LEU B 2 12  ? 170.418 201.720 177.047 1.00 8.10   ? 521 LEU B CB  1 
ATOM   3334 C CG  . LEU B 2 12  ? 171.387 200.718 176.462 1.00 7.88   ? 521 LEU B CG  1 
ATOM   3335 C CD1 . LEU B 2 12  ? 171.808 201.224 175.114 1.00 8.24   ? 521 LEU B CD1 1 
ATOM   3336 C CD2 . LEU B 2 12  ? 172.597 200.503 177.372 1.00 7.35   ? 521 LEU B CD2 1 
ATOM   3337 N N   . GLY B 2 13  ? 167.724 202.271 179.367 1.00 9.01   ? 522 GLY B N   1 
ATOM   3338 C CA  . GLY B 2 13  ? 166.832 203.326 179.820 1.00 8.27   ? 522 GLY B CA  1 
ATOM   3339 C C   . GLY B 2 13  ? 167.454 204.167 180.916 1.00 8.82   ? 522 GLY B C   1 
ATOM   3340 O O   . GLY B 2 13  ? 167.199 205.366 181.032 1.00 10.16  ? 522 GLY B O   1 
ATOM   3341 N N   . ALA B 2 14  ? 168.299 203.534 181.713 1.00 9.12   ? 523 ALA B N   1 
ATOM   3342 C CA  . ALA B 2 14  ? 168.988 204.140 182.832 1.00 6.67   ? 523 ALA B CA  1 
ATOM   3343 C C   . ALA B 2 14  ? 170.282 204.806 182.423 1.00 6.70   ? 523 ALA B C   1 
ATOM   3344 O O   . ALA B 2 14  ? 170.990 205.333 183.264 1.00 7.42   ? 523 ALA B O   1 
ATOM   3345 C CB  . ALA B 2 14  ? 169.284 203.107 183.882 1.00 7.17   ? 523 ALA B CB  1 
ATOM   3346 N N   . ALA B 2 15  ? 170.618 204.821 181.146 1.00 8.59   ? 524 ALA B N   1 
ATOM   3347 C CA  . ALA B 2 15  ? 171.891 205.386 180.724 1.00 6.44   ? 524 ALA B CA  1 
ATOM   3348 C C   . ALA B 2 15  ? 172.064 206.832 181.158 1.00 7.48   ? 524 ALA B C   1 
ATOM   3349 O O   . ALA B 2 15  ? 173.172 207.256 181.463 1.00 8.71   ? 524 ALA B O   1 
ATOM   3350 C CB  . ALA B 2 15  ? 172.019 205.275 179.228 1.00 6.43   ? 524 ALA B CB  1 
ATOM   3351 N N   . GLY B 2 16  ? 170.993 207.611 181.213 1.00 8.89   ? 525 GLY B N   1 
ATOM   3352 C CA  . GLY B 2 16  ? 171.122 209.003 181.632 1.00 6.60   ? 525 GLY B CA  1 
ATOM   3353 C C   . GLY B 2 16  ? 170.914 209.220 183.139 1.00 8.14   ? 525 GLY B C   1 
ATOM   3354 O O   . GLY B 2 16  ? 170.962 210.354 183.614 1.00 9.03   ? 525 GLY B O   1 
ATOM   3355 N N   . SER B 2 17  ? 170.673 208.147 183.891 1.00 7.65   ? 526 SER B N   1 
ATOM   3356 C CA  . SER B 2 17  ? 170.403 208.242 185.323 1.00 6.15   ? 526 SER B CA  1 
ATOM   3357 C C   . SER B 2 17  ? 171.713 208.172 186.065 1.00 5.98   ? 526 SER B C   1 
ATOM   3358 O O   . SER B 2 17  ? 172.750 207.858 185.478 1.00 6.66   ? 526 SER B O   1 
ATOM   3359 C CB  . SER B 2 17  ? 169.501 207.139 185.798 1.00 6.15   ? 526 SER B CB  1 
ATOM   3360 O OG  . SER B 2 17  ? 170.182 205.960 185.881 1.00 0.36   ? 526 SER B OG  1 
ATOM   3361 N N   . THR B 2 18  ? 171.700 208.411 187.373 1.00 7.07   ? 527 THR B N   1 
ATOM   3362 C CA  . THR B 2 18  ? 172.889 208.442 188.259 1.00 4.98   ? 527 THR B CA  1 
ATOM   3363 C C   . THR B 2 18  ? 173.364 207.021 188.476 1.00 5.56   ? 527 THR B C   1 
ATOM   3364 O O   . THR B 2 18  ? 172.561 206.137 188.370 1.00 8.29   ? 527 THR B O   1 
ATOM   3365 C CB  . THR B 2 18  ? 172.585 209.167 189.572 1.00 5.45   ? 527 THR B CB  1 
ATOM   3366 O OG1 . THR B 2 18  ? 171.718 208.361 190.363 1.00 7.10   ? 527 THR B OG1 1 
ATOM   3367 C CG2 . THR B 2 18  ? 171.984 210.537 189.376 1.00 6.54   ? 527 THR B CG2 1 
ATOM   3368 N N   . MET B 2 19  ? 174.648 206.836 188.740 1.00 5.28   ? 528 MET B N   1 
ATOM   3369 C CA  . MET B 2 19  ? 175.219 205.523 188.962 1.00 4.14   ? 528 MET B CA  1 
ATOM   3370 C C   . MET B 2 19  ? 174.488 204.710 190.006 1.00 4.95   ? 528 MET B C   1 
ATOM   3371 O O   . MET B 2 19  ? 174.312 203.504 189.831 1.00 6.16   ? 528 MET B O   1 
ATOM   3372 C CB  . MET B 2 19  ? 176.686 205.657 189.319 1.00 3.82   ? 528 MET B CB  1 
ATOM   3373 C CG  . MET B 2 19  ? 177.553 206.085 188.218 1.00 3.69   ? 528 MET B CG  1 
ATOM   3374 S SD  . MET B 2 19  ? 179.185 206.462 188.698 1.00 4.07   ? 528 MET B SD  1 
ATOM   3375 C CE  . MET B 2 19  ? 179.907 204.968 189.171 1.00 2.45   ? 528 MET B CE  1 
ATOM   3376 N N   . GLY B 2 20  ? 174.017 205.342 191.071 1.00 5.68   ? 529 GLY B N   1 
ATOM   3377 C CA  . GLY B 2 20  ? 173.333 204.620 192.127 1.00 5.11   ? 529 GLY B CA  1 
ATOM   3378 C C   . GLY B 2 20  ? 171.926 204.181 191.750 1.00 6.33   ? 529 GLY B C   1 
ATOM   3379 O O   . GLY B 2 20  ? 171.300 203.430 192.490 1.00 8.95   ? 529 GLY B O   1 
ATOM   3380 N N   . ALA B 2 21  ? 171.398 204.687 190.641 1.00 7.45   ? 530 ALA B N   1 
ATOM   3381 C CA  . ALA B 2 21  ? 170.074 204.333 190.168 1.00 5.86   ? 530 ALA B CA  1 
ATOM   3382 C C   . ALA B 2 21  ? 170.195 203.285 189.082 1.00 6.21   ? 530 ALA B C   1 
ATOM   3383 O O   . ALA B 2 21  ? 169.463 202.300 189.042 1.00 7.61   ? 530 ALA B O   1 
ATOM   3384 C CB  . ALA B 2 21  ? 169.373 205.553 189.632 1.00 5.60   ? 530 ALA B CB  1 
ATOM   3385 N N   . ALA B 2 22  ? 171.182 203.488 188.222 1.00 6.98   ? 531 ALA B N   1 
ATOM   3386 C CA  . ALA B 2 22  ? 171.488 202.649 187.090 1.00 5.83   ? 531 ALA B CA  1 
ATOM   3387 C C   . ALA B 2 22  ? 171.985 201.291 187.527 1.00 7.01   ? 531 ALA B C   1 
ATOM   3388 O O   . ALA B 2 22  ? 171.802 200.301 186.821 1.00 7.94   ? 531 ALA B O   1 
ATOM   3389 C CB  . ALA B 2 22  ? 172.509 203.332 186.234 1.00 5.90   ? 531 ALA B CB  1 
ATOM   3390 N N   . SER B 2 23  ? 172.595 201.216 188.706 1.00 7.31   ? 532 SER B N   1 
ATOM   3391 C CA  . SER B 2 23  ? 173.111 199.976 189.257 1.00 6.49   ? 532 SER B CA  1 
ATOM   3392 C C   . SER B 2 23  ? 171.985 199.009 189.603 1.00 7.22   ? 532 SER B C   1 
ATOM   3393 O O   . SER B 2 23  ? 172.226 197.837 189.861 1.00 8.77   ? 532 SER B O   1 
ATOM   3394 C CB  . SER B 2 23  ? 173.957 200.243 190.478 1.00 5.99   ? 532 SER B CB  1 
ATOM   3395 O OG  . SER B 2 23  ? 173.182 200.706 191.536 1.00 8.52   ? 532 SER B OG  1 
ATOM   3396 N N   . MET B 2 24  ? 170.743 199.472 189.618 1.00 7.99   ? 533 MET B N   1 
ATOM   3397 C CA  . MET B 2 24  ? 169.625 198.601 189.907 1.00 5.96   ? 533 MET B CA  1 
ATOM   3398 C C   . MET B 2 24  ? 169.025 197.954 188.657 1.00 7.76   ? 533 MET B C   1 
ATOM   3399 O O   . MET B 2 24  ? 168.051 197.211 188.755 1.00 9.63   ? 533 MET B O   1 
ATOM   3400 C CB  . MET B 2 24  ? 168.585 199.369 190.684 1.00 0.04   ? 533 MET B CB  1 
ATOM   3401 C CG  . MET B 2 24  ? 169.068 199.737 192.062 1.00 0.03   ? 533 MET B CG  1 
ATOM   3402 S SD  . MET B 2 24  ? 167.818 200.447 193.085 1.00 8.30   ? 533 MET B SD  1 
ATOM   3403 C CE  . MET B 2 24  ? 167.773 202.118 192.490 1.00 0.00   ? 533 MET B CE  1 
ATOM   3404 N N   . THR B 2 25  ? 169.600 198.220 187.479 1.00 8.84   ? 534 THR B N   1 
ATOM   3405 C CA  . THR B 2 25  ? 169.077 197.699 186.215 1.00 7.78   ? 534 THR B CA  1 
ATOM   3406 C C   . THR B 2 25  ? 170.088 196.774 185.538 1.00 8.49   ? 534 THR B C   1 
ATOM   3407 O O   . THR B 2 25  ? 170.017 196.523 184.337 1.00 11.09  ? 534 THR B O   1 
ATOM   3408 C CB  . THR B 2 25  ? 168.762 198.824 185.226 1.00 9.01   ? 534 THR B CB  1 
ATOM   3409 O OG1 . THR B 2 25  ? 169.955 199.522 184.874 1.00 9.68   ? 534 THR B OG1 1 
ATOM   3410 C CG2 . THR B 2 25  ? 167.805 199.808 185.856 1.00 7.50   ? 534 THR B CG2 1 
ATOM   3411 N N   . LEU B 2 26  ? 171.008 196.221 186.297 1.00 8.96   ? 535 LEU B N   1 
ATOM   3412 C CA  . LEU B 2 26  ? 172.077 195.430 185.712 1.00 7.23   ? 535 LEU B CA  1 
ATOM   3413 C C   . LEU B 2 26  ? 171.584 194.199 184.944 1.00 8.00   ? 535 LEU B C   1 
ATOM   3414 O O   . LEU B 2 26  ? 172.221 193.786 183.971 1.00 9.32   ? 535 LEU B O   1 
ATOM   3415 C CB  . LEU B 2 26  ? 173.037 195.000 186.811 1.00 7.21   ? 535 LEU B CB  1 
ATOM   3416 C CG  . LEU B 2 26  ? 173.813 196.125 187.550 1.00 5.57   ? 535 LEU B CG  1 
ATOM   3417 C CD1 . LEU B 2 26  ? 174.586 195.507 188.654 1.00 5.64   ? 535 LEU B CD1 1 
ATOM   3418 C CD2 . LEU B 2 26  ? 174.735 196.903 186.655 1.00 6.37   ? 535 LEU B CD2 1 
ATOM   3419 N N   . THR B 2 27  ? 170.452 193.605 185.333 1.00 11.07  ? 536 THR B N   1 
ATOM   3420 C CA  . THR B 2 27  ? 169.951 192.438 184.617 1.00 9.92   ? 536 THR B CA  1 
ATOM   3421 C C   . THR B 2 27  ? 169.294 192.825 183.305 1.00 9.86   ? 536 THR B C   1 
ATOM   3422 O O   . THR B 2 27  ? 169.121 191.982 182.420 1.00 13.00  ? 536 THR B O   1 
ATOM   3423 C CB  . THR B 2 27  ? 168.916 191.680 185.439 1.00 10.73  ? 536 THR B CB  1 
ATOM   3424 O OG1 . THR B 2 27  ? 167.851 192.567 185.758 1.00 12.01  ? 536 THR B OG1 1 
ATOM   3425 C CG2 . THR B 2 27  ? 169.498 191.127 186.669 1.00 10.98  ? 536 THR B CG2 1 
ATOM   3426 N N   . VAL B 2 28  ? 168.939 194.095 183.156 1.00 11.09  ? 537 VAL B N   1 
ATOM   3427 C CA  . VAL B 2 28  ? 168.281 194.558 181.961 1.00 9.64   ? 537 VAL B CA  1 
ATOM   3428 C C   . VAL B 2 28  ? 169.303 194.558 180.859 1.00 9.56   ? 537 VAL B C   1 
ATOM   3429 O O   . VAL B 2 28  ? 169.037 194.094 179.756 1.00 11.77  ? 537 VAL B O   1 
ATOM   3430 C CB  . VAL B 2 28  ? 167.696 195.959 182.151 1.00 9.42   ? 537 VAL B CB  1 
ATOM   3431 C CG1 . VAL B 2 28  ? 167.154 196.458 180.874 1.00 10.81  ? 537 VAL B CG1 1 
ATOM   3432 C CG2 . VAL B 2 28  ? 166.634 195.925 183.211 1.00 9.54   ? 537 VAL B CG2 1 
ATOM   3433 N N   . GLN B 2 29  ? 170.486 195.058 181.166 1.00 11.11  ? 538 GLN B N   1 
ATOM   3434 C CA  . GLN B 2 29  ? 171.522 195.063 180.157 1.00 8.85   ? 538 GLN B CA  1 
ATOM   3435 C C   . GLN B 2 29  ? 172.173 193.701 180.003 1.00 9.42   ? 538 GLN B C   1 
ATOM   3436 O O   . GLN B 2 29  ? 172.447 193.280 178.888 1.00 12.11  ? 538 GLN B O   1 
ATOM   3437 C CB  . GLN B 2 29  ? 172.584 196.118 180.443 1.00 8.78   ? 538 GLN B CB  1 
ATOM   3438 C CG  . GLN B 2 29  ? 172.200 197.577 180.141 1.00 7.64   ? 538 GLN B CG  1 
ATOM   3439 C CD  . GLN B 2 29  ? 171.228 198.202 181.097 1.00 7.53   ? 538 GLN B CD  1 
ATOM   3440 O OE1 . GLN B 2 29  ? 170.161 198.697 180.679 1.00 9.40   ? 538 GLN B OE1 1 
ATOM   3441 N NE2 . GLN B 2 29  ? 171.566 198.215 182.376 1.00 7.32   ? 538 GLN B NE2 1 
ATOM   3442 N N   . ALA B 2 30  ? 172.373 192.947 181.084 1.00 11.74  ? 539 ALA B N   1 
ATOM   3443 C CA  . ALA B 2 30  ? 173.034 191.656 180.938 1.00 10.02  ? 539 ALA B CA  1 
ATOM   3444 C C   . ALA B 2 30  ? 172.271 190.730 179.990 1.00 11.41  ? 539 ALA B C   1 
ATOM   3445 O O   . ALA B 2 30  ? 172.867 190.049 179.147 1.00 14.60  ? 539 ALA B O   1 
ATOM   3446 C CB  . ALA B 2 30  ? 173.170 190.982 182.289 1.00 9.43   ? 539 ALA B CB  1 
ATOM   3447 N N   . ARG B 2 31  ? 170.950 190.771 180.024 1.00 13.28  ? 540 ARG B N   1 
ATOM   3448 C CA  . ARG B 2 31  ? 170.150 189.891 179.186 1.00 12.63  ? 540 ARG B CA  1 
ATOM   3449 C C   . ARG B 2 31  ? 170.098 190.278 177.722 1.00 13.32  ? 540 ARG B C   1 
ATOM   3450 O O   . ARG B 2 31  ? 169.547 189.541 176.914 1.00 16.36  ? 540 ARG B O   1 
ATOM   3451 C CB  . ARG B 2 31  ? 168.747 189.768 179.713 1.00 14.21  ? 540 ARG B CB  1 
ATOM   3452 C CG  . ARG B 2 31  ? 168.649 189.030 181.011 1.00 16.33  ? 540 ARG B CG  1 
ATOM   3453 C CD  . ARG B 2 31  ? 167.275 189.013 181.529 1.00 20.49  ? 540 ARG B CD  1 
ATOM   3454 N NE  . ARG B 2 31  ? 166.837 190.339 181.938 1.00 17.16  ? 540 ARG B NE  1 
ATOM   3455 C CZ  . ARG B 2 31  ? 165.566 190.683 182.206 1.00 15.10  ? 540 ARG B CZ  1 
ATOM   3456 N NH1 . ARG B 2 31  ? 164.604 189.795 182.089 1.00 0.79   ? 540 ARG B NH1 1 
ATOM   3457 N NH2 . ARG B 2 31  ? 165.275 191.913 182.596 1.00 0.00   ? 540 ARG B NH2 1 
ATOM   3458 N N   . ASN B 2 32  ? 170.626 191.436 177.366 1.00 14.37  ? 541 ASN B N   1 
ATOM   3459 C CA  . ASN B 2 32  ? 170.631 191.880 175.986 1.00 12.49  ? 541 ASN B CA  1 
ATOM   3460 C C   . ASN B 2 32  ? 172.008 191.743 175.354 1.00 13.21  ? 541 ASN B C   1 
ATOM   3461 O O   . ASN B 2 32  ? 172.270 192.266 174.267 1.00 14.59  ? 541 ASN B O   1 
ATOM   3462 C CB  . ASN B 2 32  ? 170.084 193.275 175.890 1.00 13.26  ? 541 ASN B CB  1 
ATOM   3463 C CG  . ASN B 2 32  ? 168.596 193.311 176.026 1.00 14.58  ? 541 ASN B CG  1 
ATOM   3464 O OD1 . ASN B 2 32  ? 167.914 193.020 175.037 1.00 17.75  ? 541 ASN B OD1 1 
ATOM   3465 N ND2 . ASN B 2 32  ? 168.056 193.622 177.167 1.00 13.53  ? 541 ASN B ND2 1 
ATOM   3466 N N   . LEU B 2 33  ? 172.889 190.995 176.012 1.00 13.99  ? 542 LEU B N   1 
ATOM   3467 C CA  . LEU B 2 33  ? 174.207 190.765 175.455 1.00 12.65  ? 542 LEU B CA  1 
ATOM   3468 C C   . LEU B 2 33  ? 174.200 189.512 174.588 1.00 13.48  ? 542 LEU B C   1 
ATOM   3469 O O   . LEU B 2 33  ? 175.026 189.363 173.693 1.00 14.15  ? 542 LEU B O   1 
ATOM   3470 C CB  . LEU B 2 33  ? 175.224 190.633 176.580 1.00 12.81  ? 542 LEU B CB  1 
ATOM   3471 C CG  . LEU B 2 33  ? 175.368 191.866 177.515 1.00 11.60  ? 542 LEU B CG  1 
ATOM   3472 C CD1 . LEU B 2 33  ? 176.325 191.506 178.626 1.00 11.64  ? 542 LEU B CD1 1 
ATOM   3473 C CD2 . LEU B 2 33  ? 175.843 193.113 176.750 1.00 10.12  ? 542 LEU B CD2 1 
ATOM   3474 N N   . LEU B 2 34  ? 173.268 188.603 174.844 1.00 15.37  ? 543 LEU B N   1 
ATOM   3475 C CA  . LEU B 2 34  ? 173.150 187.370 174.085 1.00 16.20  ? 543 LEU B CA  1 
ATOM   3476 C C   . LEU B 2 34  ? 171.839 187.378 173.306 1.00 18.34  ? 543 LEU B C   1 
ATOM   3477 O O   . LEU B 2 34  ? 170.776 187.486 173.912 1.00 20.61  ? 543 LEU B O   1 
ATOM   3478 C CB  . LEU B 2 34  ? 173.154 186.147 175.020 1.00 14.98  ? 543 LEU B CB  1 
ATOM   3479 C CG  . LEU B 2 34  ? 174.408 185.862 175.844 1.00 10.55  ? 543 LEU B CG  1 
ATOM   3480 C CD1 . LEU B 2 34  ? 174.104 184.740 176.809 1.00 9.63   ? 543 LEU B CD1 1 
ATOM   3481 C CD2 . LEU B 2 34  ? 175.547 185.435 174.921 1.00 10.46  ? 543 LEU B CD2 1 
ATOM   3482 N N   . SER B 2 35  ? 171.910 187.229 171.959 1.00 22.84  ? 544 SER B N   1 
ATOM   3483 C CA  . SER B 2 35  ? 170.780 187.244 170.997 1.00 28.22  ? 544 SER B CA  1 
ATOM   3484 C C   . SER B 2 35  ? 169.650 188.225 171.401 1.00 30.45  ? 544 SER B C   1 
ATOM   3485 O O   . SER B 2 35  ? 169.418 189.244 170.740 1.00 30.76  ? 544 SER B O   1 
ATOM   3486 C CB  . SER B 2 35  ? 170.222 185.824 170.797 1.00 28.05  ? 544 SER B CB  1 
ATOM   3487 O OG  . SER B 2 35  ? 169.156 185.818 169.891 1.00 31.85  ? 544 SER B OG  1 
ATOM   3488 N N   . HIS B 2 59  ? 180.339 185.337 150.098 1.00 70.21  ? 570 HIS B N   1 
ATOM   3489 C CA  . HIS B 2 59  ? 179.088 184.603 150.189 1.00 48.64  ? 570 HIS B CA  1 
ATOM   3490 C C   . HIS B 2 59  ? 178.168 185.312 151.210 1.00 58.93  ? 570 HIS B C   1 
ATOM   3491 O O   . HIS B 2 59  ? 178.635 185.783 152.268 1.00 55.61  ? 570 HIS B O   1 
ATOM   3492 C CB  . HIS B 2 59  ? 179.319 183.099 150.563 1.00 53.44  ? 570 HIS B CB  1 
ATOM   3493 C CG  . HIS B 2 59  ? 178.028 182.220 150.547 1.00 61.36  ? 570 HIS B CG  1 
ATOM   3494 N ND1 . HIS B 2 59  ? 177.428 181.811 149.372 1.00 113.34 ? 570 HIS B ND1 1 
ATOM   3495 C CD2 . HIS B 2 59  ? 177.245 181.740 151.557 1.00 55.34  ? 570 HIS B CD2 1 
ATOM   3496 C CE1 . HIS B 2 59  ? 176.337 181.110 149.663 1.00 60.59  ? 570 HIS B CE1 1 
ATOM   3497 N NE2 . HIS B 2 59  ? 176.209 181.058 150.982 1.00 108.13 ? 570 HIS B NE2 1 
ATOM   3498 N N   . TRP B 2 60  ? 176.869 185.470 150.851 1.00 66.35  ? 571 TRP B N   1 
ATOM   3499 C CA  . TRP B 2 60  ? 175.869 186.149 151.685 1.00 67.99  ? 571 TRP B CA  1 
ATOM   3500 C C   . TRP B 2 60  ? 175.539 185.265 152.883 1.00 68.78  ? 571 TRP B C   1 
ATOM   3501 O O   . TRP B 2 60  ? 175.356 184.058 152.744 1.00 62.81  ? 571 TRP B O   1 
ATOM   3502 C CB  . TRP B 2 60  ? 174.590 186.427 150.906 1.00 63.22  ? 571 TRP B CB  1 
ATOM   3503 C CG  . TRP B 2 60  ? 173.667 187.353 151.636 1.00 62.44  ? 571 TRP B CG  1 
ATOM   3504 C CD1 . TRP B 2 60  ? 172.688 187.012 152.511 1.00 65.61  ? 571 TRP B CD1 1 
ATOM   3505 C CD2 . TRP B 2 60  ? 173.612 188.802 151.518 1.00 59.75  ? 571 TRP B CD2 1 
ATOM   3506 N NE1 . TRP B 2 60  ? 172.050 188.134 152.964 1.00 61.12  ? 571 TRP B NE1 1 
ATOM   3507 C CE2 . TRP B 2 60  ? 172.598 189.237 152.359 1.00 58.66  ? 571 TRP B CE2 1 
ATOM   3508 C CE3 . TRP B 2 60  ? 174.335 189.749 150.768 1.00 54.07  ? 571 TRP B CE3 1 
ATOM   3509 C CZ2 . TRP B 2 60  ? 172.275 190.580 152.484 1.00 35.72  ? 571 TRP B CZ2 1 
ATOM   3510 C CZ3 . TRP B 2 60  ? 174.005 191.095 150.893 1.00 47.09  ? 571 TRP B CZ3 1 
ATOM   3511 C CH2 . TRP B 2 60  ? 173.003 191.494 151.731 1.00 38.50  ? 571 TRP B CH2 1 
ATOM   3512 N N   . GLY B 2 61  ? 175.478 185.865 154.053 1.00 54.26  ? 572 GLY B N   1 
ATOM   3513 C CA  . GLY B 2 61  ? 175.180 185.129 155.273 1.00 46.43  ? 572 GLY B CA  1 
ATOM   3514 C C   . GLY B 2 61  ? 176.438 184.788 156.066 1.00 39.09  ? 572 GLY B C   1 
ATOM   3515 O O   . GLY B 2 61  ? 176.349 184.398 157.237 1.00 40.19  ? 572 GLY B O   1 
ATOM   3516 N N   . ILE B 2 62  ? 177.615 184.958 155.463 1.00 41.74  ? 573 ILE B N   1 
ATOM   3517 C CA  . ILE B 2 62  ? 178.836 184.640 156.182 1.00 38.32  ? 573 ILE B CA  1 
ATOM   3518 C C   . ILE B 2 62  ? 179.181 185.750 157.119 1.00 36.83  ? 573 ILE B C   1 
ATOM   3519 O O   . ILE B 2 62  ? 179.648 185.491 158.223 1.00 37.23  ? 573 ILE B O   1 
ATOM   3520 C CB  . ILE B 2 62  ? 180.002 184.340 155.256 1.00 41.84  ? 573 ILE B CB  1 
ATOM   3521 C CG1 . ILE B 2 62  ? 179.620 183.179 154.356 1.00 96.71  ? 573 ILE B CG1 1 
ATOM   3522 C CG2 . ILE B 2 62  ? 181.286 184.035 156.052 1.00 37.25  ? 573 ILE B CG2 1 
ATOM   3523 C CD1 . ILE B 2 62  ? 179.135 181.930 155.030 1.00 42.38  ? 573 ILE B CD1 1 
ATOM   3524 N N   . LYS B 2 63  ? 179.018 186.987 156.682 1.00 37.20  ? 574 LYS B N   1 
ATOM   3525 C CA  . LYS B 2 63  ? 179.330 188.090 157.556 1.00 34.69  ? 574 LYS B CA  1 
ATOM   3526 C C   . LYS B 2 63  ? 178.374 188.105 158.758 1.00 32.74  ? 574 LYS B C   1 
ATOM   3527 O O   . LYS B 2 63  ? 178.757 188.553 159.840 1.00 31.21  ? 574 LYS B O   1 
ATOM   3528 C CB  . LYS B 2 63  ? 179.368 189.392 156.762 1.00 36.24  ? 574 LYS B CB  1 
ATOM   3529 C CG  . LYS B 2 63  ? 178.058 189.871 156.156 1.00 39.39  ? 574 LYS B CG  1 
ATOM   3530 C CD  . LYS B 2 63  ? 178.297 191.154 155.387 1.00 40.22  ? 574 LYS B CD  1 
ATOM   3531 C CE  . LYS B 2 63  ? 177.017 191.795 154.872 1.00 41.08  ? 574 LYS B CE  1 
ATOM   3532 N NZ  . LYS B 2 63  ? 177.336 193.015 154.085 1.00 38.60  ? 574 LYS B NZ  1 
ATOM   3533 N N   . GLN B 2 64  ? 177.167 187.544 158.604 1.00 32.93  ? 575 GLN B N   1 
ATOM   3534 C CA  . GLN B 2 64  ? 176.262 187.445 159.731 1.00 30.56  ? 575 GLN B CA  1 
ATOM   3535 C C   . GLN B 2 64  ? 176.775 186.371 160.701 1.00 28.57  ? 575 GLN B C   1 
ATOM   3536 O O   . GLN B 2 64  ? 176.737 186.582 161.917 1.00 27.77  ? 575 GLN B O   1 
ATOM   3537 C CB  . GLN B 2 64  ? 174.839 187.156 159.275 1.00 36.38  ? 575 GLN B CB  1 
ATOM   3538 C CG  . GLN B 2 64  ? 174.165 188.319 158.522 1.00 36.54  ? 575 GLN B CG  1 
ATOM   3539 C CD  . GLN B 2 64  ? 174.503 188.365 157.025 1.00 46.19  ? 575 GLN B CD  1 
ATOM   3540 O OE1 . GLN B 2 64  ? 175.592 187.966 156.586 1.00 40.64  ? 575 GLN B OE1 1 
ATOM   3541 N NE2 . GLN B 2 64  ? 173.555 188.845 156.233 1.00 47.66  ? 575 GLN B NE2 1 
ATOM   3542 N N   . LEU B 2 65  ? 177.314 185.248 160.196 1.00 30.30  ? 576 LEU B N   1 
ATOM   3543 C CA  . LEU B 2 65  ? 177.911 184.290 161.121 1.00 24.61  ? 576 LEU B CA  1 
ATOM   3544 C C   . LEU B 2 65  ? 179.106 184.881 161.812 1.00 22.44  ? 576 LEU B C   1 
ATOM   3545 O O   . LEU B 2 65  ? 179.317 184.610 162.988 1.00 25.08  ? 576 LEU B O   1 
ATOM   3546 C CB  . LEU B 2 65  ? 178.363 182.983 160.464 1.00 27.10  ? 576 LEU B CB  1 
ATOM   3547 C CG  . LEU B 2 65  ? 177.311 181.980 160.054 1.00 29.33  ? 576 LEU B CG  1 
ATOM   3548 C CD1 . LEU B 2 65  ? 177.964 180.878 159.220 1.00 29.03  ? 576 LEU B CD1 1 
ATOM   3549 C CD2 . LEU B 2 65  ? 176.716 181.340 161.318 1.00 24.81  ? 576 LEU B CD2 1 
ATOM   3550 N N   . GLN B 2 66  ? 179.892 185.689 161.114 1.00 24.65  ? 577 GLN B N   1 
ATOM   3551 C CA  . GLN B 2 66  ? 181.049 186.266 161.764 1.00 23.90  ? 577 GLN B CA  1 
ATOM   3552 C C   . GLN B 2 66  ? 180.600 187.171 162.890 1.00 24.43  ? 577 GLN B C   1 
ATOM   3553 O O   . GLN B 2 66  ? 181.202 187.157 163.962 1.00 27.29  ? 577 GLN B O   1 
ATOM   3554 C CB  . GLN B 2 66  ? 181.882 187.072 160.776 1.00 29.78  ? 577 GLN B CB  1 
ATOM   3555 C CG  . GLN B 2 66  ? 182.610 186.256 159.737 1.00 30.30  ? 577 GLN B CG  1 
ATOM   3556 C CD  . GLN B 2 66  ? 183.238 187.104 158.690 1.00 34.44  ? 577 GLN B CD  1 
ATOM   3557 O OE1 . GLN B 2 66  ? 182.908 188.286 158.567 1.00 34.17  ? 577 GLN B OE1 1 
ATOM   3558 N NE2 . GLN B 2 66  ? 184.144 186.530 157.921 1.00 37.47  ? 577 GLN B NE2 1 
ATOM   3559 N N   . ALA B 2 67  ? 179.528 187.937 162.683 1.00 24.80  ? 578 ALA B N   1 
ATOM   3560 C CA  . ALA B 2 67  ? 179.030 188.809 163.729 1.00 22.02  ? 578 ALA B CA  1 
ATOM   3561 C C   . ALA B 2 67  ? 178.550 188.027 164.946 1.00 20.92  ? 578 ALA B C   1 
ATOM   3562 O O   . ALA B 2 67  ? 178.769 188.457 166.081 1.00 23.69  ? 578 ALA B O   1 
ATOM   3563 C CB  . ALA B 2 67  ? 177.895 189.655 163.191 1.00 23.70  ? 578 ALA B CB  1 
ATOM   3564 N N   . ARG B 2 68  ? 177.906 186.880 164.721 1.00 22.14  ? 579 ARG B N   1 
ATOM   3565 C CA  . ARG B 2 68  ? 177.400 186.070 165.822 1.00 19.74  ? 579 ARG B CA  1 
ATOM   3566 C C   . ARG B 2 68  ? 178.510 185.373 166.583 1.00 17.88  ? 579 ARG B C   1 
ATOM   3567 O O   . ARG B 2 68  ? 178.490 185.333 167.816 1.00 20.15  ? 579 ARG B O   1 
ATOM   3568 C CB  . ARG B 2 68  ? 176.413 185.059 165.297 1.00 22.12  ? 579 ARG B CB  1 
ATOM   3569 C CG  . ARG B 2 68  ? 175.136 185.685 164.838 1.00 23.15  ? 579 ARG B CG  1 
ATOM   3570 C CD  . ARG B 2 68  ? 174.277 184.764 164.100 1.00 25.35  ? 579 ARG B CD  1 
ATOM   3571 N NE  . ARG B 2 68  ? 173.711 183.709 164.914 1.00 25.56  ? 579 ARG B NE  1 
ATOM   3572 C CZ  . ARG B 2 68  ? 173.011 182.678 164.408 1.00 25.87  ? 579 ARG B CZ  1 
ATOM   3573 N NH1 . ARG B 2 68  ? 172.828 182.581 163.100 1.00 29.00  ? 579 ARG B NH1 1 
ATOM   3574 N NH2 . ARG B 2 68  ? 172.491 181.780 165.210 1.00 25.09  ? 579 ARG B NH2 1 
ATOM   3575 N N   . VAL B 2 69  ? 179.512 184.880 165.868 1.00 20.52  ? 580 VAL B N   1 
ATOM   3576 C CA  . VAL B 2 69  ? 180.622 184.214 166.508 1.00 17.96  ? 580 VAL B CA  1 
ATOM   3577 C C   . VAL B 2 69  ? 181.380 185.225 167.325 1.00 17.54  ? 580 VAL B C   1 
ATOM   3578 O O   . VAL B 2 69  ? 181.768 184.931 168.454 1.00 19.78  ? 580 VAL B O   1 
ATOM   3579 C CB  . VAL B 2 69  ? 181.532 183.512 165.485 1.00 19.78  ? 580 VAL B CB  1 
ATOM   3580 C CG1 . VAL B 2 69  ? 182.816 182.977 166.155 1.00 21.08  ? 580 VAL B CG1 1 
ATOM   3581 C CG2 . VAL B 2 69  ? 180.769 182.357 164.877 1.00 19.09  ? 580 VAL B CG2 1 
ATOM   3582 N N   . LEU B 2 70  ? 181.582 186.415 166.772 1.00 21.12  ? 581 LEU B N   1 
ATOM   3583 C CA  . LEU B 2 70  ? 182.293 187.456 167.462 1.00 18.98  ? 581 LEU B CA  1 
ATOM   3584 C C   . LEU B 2 70  ? 181.550 187.897 168.712 1.00 17.19  ? 581 LEU B C   1 
ATOM   3585 O O   . LEU B 2 70  ? 182.188 188.149 169.734 1.00 19.00  ? 581 LEU B O   1 
ATOM   3586 C CB  . LEU B 2 70  ? 182.476 188.650 166.533 1.00 22.92  ? 581 LEU B CB  1 
ATOM   3587 C CG  . LEU B 2 70  ? 183.271 189.851 167.060 1.00 27.53  ? 581 LEU B CG  1 
ATOM   3588 C CD1 . LEU B 2 70  ? 184.704 189.427 167.408 1.00 30.58  ? 581 LEU B CD1 1 
ATOM   3589 C CD2 . LEU B 2 70  ? 183.265 190.937 166.001 1.00 31.31  ? 581 LEU B CD2 1 
ATOM   3590 N N   . ALA B 2 71  ? 180.218 188.023 168.650 1.00 16.90  ? 582 ALA B N   1 
ATOM   3591 C CA  . ALA B 2 71  ? 179.463 188.417 169.825 1.00 14.97  ? 582 ALA B CA  1 
ATOM   3592 C C   . ALA B 2 71  ? 179.645 187.407 170.948 1.00 14.03  ? 582 ALA B C   1 
ATOM   3593 O O   . ALA B 2 71  ? 179.823 187.796 172.107 1.00 14.42  ? 582 ALA B O   1 
ATOM   3594 C CB  . ALA B 2 71  ? 177.994 188.546 169.482 1.00 16.04  ? 582 ALA B CB  1 
ATOM   3595 N N   . VAL B 2 72  ? 179.683 186.115 170.606 1.00 15.77  ? 583 VAL B N   1 
ATOM   3596 C CA  . VAL B 2 72  ? 179.901 185.088 171.609 1.00 12.47  ? 583 VAL B CA  1 
ATOM   3597 C C   . VAL B 2 72  ? 181.284 185.185 172.195 1.00 11.75  ? 583 VAL B C   1 
ATOM   3598 O O   . VAL B 2 72  ? 181.439 185.063 173.407 1.00 12.21  ? 583 VAL B O   1 
ATOM   3599 C CB  . VAL B 2 72  ? 179.685 183.675 171.049 1.00 13.01  ? 583 VAL B CB  1 
ATOM   3600 C CG1 . VAL B 2 72  ? 180.141 182.636 172.061 1.00 13.64  ? 583 VAL B CG1 1 
ATOM   3601 C CG2 . VAL B 2 72  ? 178.213 183.477 170.765 1.00 14.46  ? 583 VAL B CG2 1 
ATOM   3602 N N   . GLU B 2 73  ? 182.294 185.382 171.359 1.00 14.80  ? 584 GLU B N   1 
ATOM   3603 C CA  . GLU B 2 73  ? 183.648 185.480 171.856 1.00 12.40  ? 584 GLU B CA  1 
ATOM   3604 C C   . GLU B 2 73  ? 183.805 186.676 172.782 1.00 11.75  ? 584 GLU B C   1 
ATOM   3605 O O   . GLU B 2 73  ? 184.469 186.571 173.813 1.00 14.22  ? 584 GLU B O   1 
ATOM   3606 C CB  . GLU B 2 73  ? 184.614 185.598 170.685 1.00 16.68  ? 584 GLU B CB  1 
ATOM   3607 C CG  . GLU B 2 73  ? 184.792 184.339 169.845 1.00 17.61  ? 584 GLU B CG  1 
ATOM   3608 C CD  . GLU B 2 73  ? 185.539 184.626 168.565 1.00 21.49  ? 584 GLU B CD  1 
ATOM   3609 O OE1 . GLU B 2 73  ? 185.716 185.780 168.269 1.00 22.65  ? 584 GLU B OE1 1 
ATOM   3610 O OE2 . GLU B 2 73  ? 185.942 183.718 167.882 1.00 23.41  ? 584 GLU B OE2 1 
ATOM   3611 N N   . HIS B 2 74  ? 183.174 187.805 172.455 1.00 13.69  ? 585 HIS B N   1 
ATOM   3612 C CA  . HIS B 2 74  ? 183.268 188.978 173.304 1.00 12.23  ? 585 HIS B CA  1 
ATOM   3613 C C   . HIS B 2 74  ? 182.665 188.658 174.663 1.00 10.83  ? 585 HIS B C   1 
ATOM   3614 O O   . HIS B 2 74  ? 183.273 188.918 175.706 1.00 14.61  ? 585 HIS B O   1 
ATOM   3615 C CB  . HIS B 2 74  ? 182.537 190.179 172.706 1.00 15.61  ? 585 HIS B CB  1 
ATOM   3616 C CG  . HIS B 2 74  ? 182.724 191.427 173.522 1.00 18.12  ? 585 HIS B CG  1 
ATOM   3617 N ND1 . HIS B 2 74  ? 183.791 192.316 173.339 1.00 18.19  ? 585 HIS B ND1 1 
ATOM   3618 C CD2 . HIS B 2 74  ? 182.026 191.899 174.575 1.00 20.23  ? 585 HIS B CD2 1 
ATOM   3619 C CE1 . HIS B 2 74  ? 183.719 193.255 174.278 1.00 18.65  ? 585 HIS B CE1 1 
ATOM   3620 N NE2 . HIS B 2 74  ? 182.662 193.029 175.012 1.00 18.13  ? 585 HIS B NE2 1 
ATOM   3621 N N   . TYR B 2 75  ? 181.468 188.067 174.659 1.00 11.69  ? 586 TYR B N   1 
ATOM   3622 C CA  . TYR B 2 75  ? 180.771 187.716 175.880 1.00 8.64   ? 586 TYR B CA  1 
ATOM   3623 C C   . TYR B 2 75  ? 181.625 186.838 176.763 1.00 8.02   ? 586 TYR B C   1 
ATOM   3624 O O   . TYR B 2 75  ? 181.747 187.099 177.965 1.00 9.35   ? 586 TYR B O   1 
ATOM   3625 C CB  . TYR B 2 75  ? 179.459 187.005 175.556 1.00 8.76   ? 586 TYR B CB  1 
ATOM   3626 C CG  . TYR B 2 75  ? 178.687 186.520 176.748 1.00 8.83   ? 586 TYR B CG  1 
ATOM   3627 C CD1 . TYR B 2 75  ? 177.900 187.387 177.466 1.00 8.68   ? 586 TYR B CD1 1 
ATOM   3628 C CD2 . TYR B 2 75  ? 178.761 185.194 177.117 1.00 8.35   ? 586 TYR B CD2 1 
ATOM   3629 C CE1 . TYR B 2 75  ? 177.203 186.934 178.545 1.00 8.57   ? 586 TYR B CE1 1 
ATOM   3630 C CE2 . TYR B 2 75  ? 178.061 184.748 178.192 1.00 7.27   ? 586 TYR B CE2 1 
ATOM   3631 C CZ  . TYR B 2 75  ? 177.288 185.613 178.907 1.00 8.27   ? 586 TYR B CZ  1 
ATOM   3632 O OH  . TYR B 2 75  ? 176.593 185.168 179.994 1.00 10.21  ? 586 TYR B OH  1 
ATOM   3633 N N   . LEU B 2 76  ? 182.217 185.802 176.182 1.00 9.57   ? 587 LEU B N   1 
ATOM   3634 C CA  . LEU B 2 76  ? 183.011 184.883 176.954 1.00 7.37   ? 587 LEU B CA  1 
ATOM   3635 C C   . LEU B 2 76  ? 184.251 185.521 177.521 1.00 7.52   ? 587 LEU B C   1 
ATOM   3636 O O   . LEU B 2 76  ? 184.707 185.092 178.578 1.00 9.61   ? 587 LEU B O   1 
ATOM   3637 C CB  . LEU B 2 76  ? 183.386 183.666 176.128 1.00 8.54   ? 587 LEU B CB  1 
ATOM   3638 C CG  . LEU B 2 76  ? 182.234 182.739 175.730 1.00 7.66   ? 587 LEU B CG  1 
ATOM   3639 C CD1 . LEU B 2 76  ? 182.764 181.691 174.826 1.00 8.87   ? 587 LEU B CD1 1 
ATOM   3640 C CD2 . LEU B 2 76  ? 181.593 182.110 176.927 1.00 7.13   ? 587 LEU B CD2 1 
ATOM   3641 N N   . ARG B 2 77  ? 184.852 186.493 176.836 1.00 9.39   ? 588 ARG B N   1 
ATOM   3642 C CA  . ARG B 2 77  ? 186.030 187.118 177.408 1.00 8.12   ? 588 ARG B CA  1 
ATOM   3643 C C   . ARG B 2 77  ? 185.669 187.910 178.654 1.00 8.32   ? 588 ARG B C   1 
ATOM   3644 O O   . ARG B 2 77  ? 186.418 187.875 179.630 1.00 9.47   ? 588 ARG B O   1 
ATOM   3645 C CB  . ARG B 2 77  ? 186.758 187.990 176.417 1.00 11.35  ? 588 ARG B CB  1 
ATOM   3646 C CG  . ARG B 2 77  ? 187.482 187.206 175.351 1.00 13.38  ? 588 ARG B CG  1 
ATOM   3647 C CD  . ARG B 2 77  ? 188.446 188.019 174.576 1.00 18.14  ? 588 ARG B CD  1 
ATOM   3648 N NE  . ARG B 2 77  ? 187.819 189.133 173.854 1.00 20.10  ? 588 ARG B NE  1 
ATOM   3649 C CZ  . ARG B 2 77  ? 187.234 189.060 172.639 1.00 21.55  ? 588 ARG B CZ  1 
ATOM   3650 N NH1 . ARG B 2 77  ? 187.140 187.918 172.020 1.00 21.41  ? 588 ARG B NH1 1 
ATOM   3651 N NH2 . ARG B 2 77  ? 186.744 190.150 172.076 1.00 19.20  ? 588 ARG B NH2 1 
ATOM   3652 N N   . ASP B 2 78  ? 184.519 188.594 178.659 1.00 9.71   ? 589 ASP B N   1 
ATOM   3653 C CA  . ASP B 2 78  ? 184.129 189.339 179.857 1.00 7.88   ? 589 ASP B CA  1 
ATOM   3654 C C   . ASP B 2 78  ? 183.791 188.401 180.995 1.00 7.16   ? 589 ASP B C   1 
ATOM   3655 O O   . ASP B 2 78  ? 184.047 188.711 182.161 1.00 8.93   ? 589 ASP B O   1 
ATOM   3656 C CB  . ASP B 2 78  ? 182.933 190.246 179.610 1.00 10.44  ? 589 ASP B CB  1 
ATOM   3657 C CG  . ASP B 2 78  ? 183.235 191.504 178.815 1.00 13.10  ? 589 ASP B CG  1 
ATOM   3658 O OD1 . ASP B 2 78  ? 184.376 191.858 178.673 1.00 14.63  ? 589 ASP B OD1 1 
ATOM   3659 O OD2 . ASP B 2 78  ? 182.300 192.116 178.353 1.00 19.31  ? 589 ASP B OD2 1 
ATOM   3660 N N   . GLN B 2 79  ? 183.204 187.253 180.674 1.00 8.59   ? 590 GLN B N   1 
ATOM   3661 C CA  . GLN B 2 79  ? 182.870 186.302 181.714 1.00 6.73   ? 590 GLN B CA  1 
ATOM   3662 C C   . GLN B 2 79  ? 184.121 185.650 182.271 1.00 6.29   ? 590 GLN B C   1 
ATOM   3663 O O   . GLN B 2 79  ? 184.216 185.419 183.480 1.00 7.01   ? 590 GLN B O   1 
ATOM   3664 C CB  . GLN B 2 79  ? 181.913 185.250 181.177 1.00 7.84   ? 590 GLN B CB  1 
ATOM   3665 C CG  . GLN B 2 79  ? 180.552 185.778 180.833 1.00 7.64   ? 590 GLN B CG  1 
ATOM   3666 C CD  . GLN B 2 79  ? 179.832 186.275 182.016 1.00 8.05   ? 590 GLN B CD  1 
ATOM   3667 O OE1 . GLN B 2 79  ? 179.742 185.571 183.019 1.00 12.33  ? 590 GLN B OE1 1 
ATOM   3668 N NE2 . GLN B 2 79  ? 179.317 187.479 181.953 1.00 8.79   ? 590 GLN B NE2 1 
ATOM   3669 N N   . GLN B 2 80  ? 185.115 185.394 181.413 1.00 8.00   ? 591 GLN B N   1 
ATOM   3670 C CA  . GLN B 2 80  ? 186.358 184.807 181.863 1.00 7.15   ? 591 GLN B CA  1 
ATOM   3671 C C   . GLN B 2 80  ? 187.061 185.734 182.799 1.00 6.89   ? 591 GLN B C   1 
ATOM   3672 O O   . GLN B 2 80  ? 187.620 185.293 183.801 1.00 9.04   ? 591 GLN B O   1 
ATOM   3673 C CB  . GLN B 2 80  ? 187.314 184.517 180.718 1.00 8.79   ? 591 GLN B CB  1 
ATOM   3674 C CG  . GLN B 2 80  ? 188.590 183.834 181.179 1.00 10.41  ? 591 GLN B CG  1 
ATOM   3675 C CD  . GLN B 2 80  ? 189.532 183.564 180.099 1.00 10.11  ? 591 GLN B CD  1 
ATOM   3676 O OE1 . GLN B 2 80  ? 189.851 184.451 179.313 1.00 12.09  ? 591 GLN B OE1 1 
ATOM   3677 N NE2 . GLN B 2 80  ? 190.006 182.346 180.040 1.00 12.47  ? 591 GLN B NE2 1 
ATOM   3678 N N   . LEU B 2 81  ? 187.022 187.017 182.479 1.00 9.16   ? 592 LEU B N   1 
ATOM   3679 C CA  . LEU B 2 81  ? 187.693 188.020 183.257 1.00 6.66   ? 592 LEU B CA  1 
ATOM   3680 C C   . LEU B 2 81  ? 187.052 188.125 184.635 1.00 5.31   ? 592 LEU B C   1 
ATOM   3681 O O   . LEU B 2 81  ? 187.759 188.145 185.641 1.00 7.44   ? 592 LEU B O   1 
ATOM   3682 C CB  . LEU B 2 81  ? 187.653 189.319 182.455 1.00 6.74   ? 592 LEU B CB  1 
ATOM   3683 C CG  . LEU B 2 81  ? 188.360 190.499 182.979 1.00 7.03   ? 592 LEU B CG  1 
ATOM   3684 C CD1 . LEU B 2 81  ? 189.850 190.208 183.141 1.00 0.02   ? 592 LEU B CD1 1 
ATOM   3685 C CD2 . LEU B 2 81  ? 188.168 191.654 182.024 1.00 6.32   ? 592 LEU B CD2 1 
ATOM   3686 N N   . LEU B 2 82  ? 185.726 188.071 184.713 1.00 7.53   ? 593 LEU B N   1 
ATOM   3687 C CA  . LEU B 2 82  ? 185.101 188.090 186.022 1.00 6.39   ? 593 LEU B CA  1 
ATOM   3688 C C   . LEU B 2 82  ? 185.518 186.875 186.819 1.00 6.50   ? 593 LEU B C   1 
ATOM   3689 O O   . LEU B 2 82  ? 185.794 186.990 188.010 1.00 8.43   ? 593 LEU B O   1 
ATOM   3690 C CB  . LEU B 2 82  ? 183.577 188.072 185.892 1.00 6.98   ? 593 LEU B CB  1 
ATOM   3691 C CG  . LEU B 2 82  ? 182.892 189.321 185.377 1.00 6.74   ? 593 LEU B CG  1 
ATOM   3692 C CD1 . LEU B 2 82  ? 181.455 188.995 185.073 1.00 6.89   ? 593 LEU B CD1 1 
ATOM   3693 C CD2 . LEU B 2 82  ? 182.946 190.393 186.438 1.00 7.50   ? 593 LEU B CD2 1 
ATOM   3694 N N   . GLY B 2 83  ? 185.622 185.715 186.178 1.00 7.87   ? 594 GLY B N   1 
ATOM   3695 C CA  . GLY B 2 83  ? 186.048 184.516 186.883 1.00 7.78   ? 594 GLY B CA  1 
ATOM   3696 C C   . GLY B 2 83  ? 187.460 184.647 187.437 1.00 7.69   ? 594 GLY B C   1 
ATOM   3697 O O   . GLY B 2 83  ? 187.701 184.365 188.605 1.00 9.60   ? 594 GLY B O   1 
ATOM   3698 N N   . ILE B 2 84  ? 188.362 185.223 186.660 1.00 8.18   ? 595 ILE B N   1 
ATOM   3699 C CA  . ILE B 2 84  ? 189.746 185.440 187.063 1.00 6.58   ? 595 ILE B CA  1 
ATOM   3700 C C   . ILE B 2 84  ? 189.844 186.317 188.286 1.00 7.05   ? 595 ILE B C   1 
ATOM   3701 O O   . ILE B 2 84  ? 190.739 186.127 189.100 1.00 7.55   ? 595 ILE B O   1 
ATOM   3702 C CB  . ILE B 2 84  ? 190.607 185.971 185.910 1.00 7.98   ? 595 ILE B CB  1 
ATOM   3703 C CG1 . ILE B 2 84  ? 190.787 184.841 184.893 1.00 9.16   ? 595 ILE B CG1 1 
ATOM   3704 C CG2 . ILE B 2 84  ? 191.933 186.522 186.407 1.00 10.99  ? 595 ILE B CG2 1 
ATOM   3705 C CD1 . ILE B 2 84  ? 191.373 185.261 183.581 1.00 15.11  ? 595 ILE B CD1 1 
ATOM   3706 N N   . TRP B 2 85  ? 188.972 187.299 188.393 1.00 7.76   ? 596 TRP B N   1 
ATOM   3707 C CA  . TRP B 2 85  ? 188.923 188.216 189.519 1.00 6.15   ? 596 TRP B CA  1 
ATOM   3708 C C   . TRP B 2 85  ? 188.134 187.677 190.717 1.00 5.87   ? 596 TRP B C   1 
ATOM   3709 O O   . TRP B 2 85  ? 188.017 188.376 191.726 1.00 6.64   ? 596 TRP B O   1 
ATOM   3710 C CB  . TRP B 2 85  ? 188.220 189.484 189.105 1.00 5.61   ? 596 TRP B CB  1 
ATOM   3711 C CG  . TRP B 2 85  ? 188.864 190.224 188.058 1.00 5.13   ? 596 TRP B CG  1 
ATOM   3712 C CD1 . TRP B 2 85  ? 190.124 190.126 187.596 1.00 5.06   ? 596 TRP B CD1 1 
ATOM   3713 C CD2 . TRP B 2 85  ? 188.239 191.219 187.290 1.00 6.15   ? 596 TRP B CD2 1 
ATOM   3714 N NE1 . TRP B 2 85  ? 190.312 191.004 186.605 1.00 5.17   ? 596 TRP B NE1 1 
ATOM   3715 C CE2 . TRP B 2 85  ? 189.164 191.685 186.411 1.00 5.89   ? 596 TRP B CE2 1 
ATOM   3716 C CE3 . TRP B 2 85  ? 186.969 191.748 187.280 1.00 5.90   ? 596 TRP B CE3 1 
ATOM   3717 C CZ2 . TRP B 2 85  ? 188.870 192.653 185.540 1.00 5.70   ? 596 TRP B CZ2 1 
ATOM   3718 C CZ3 . TRP B 2 85  ? 186.683 192.721 186.392 1.00 5.52   ? 596 TRP B CZ3 1 
ATOM   3719 C CH2 . TRP B 2 85  ? 187.603 193.160 185.550 1.00 5.82   ? 596 TRP B CH2 1 
ATOM   3720 N N   . GLY B 2 86  ? 187.540 186.484 190.591 1.00 6.81   ? 597 GLY B N   1 
ATOM   3721 C CA  . GLY B 2 86  ? 186.710 185.883 191.641 1.00 5.41   ? 597 GLY B CA  1 
ATOM   3722 C C   . GLY B 2 86  ? 185.256 186.380 191.746 1.00 5.63   ? 597 GLY B C   1 
ATOM   3723 O O   . GLY B 2 86  ? 184.672 186.280 192.826 1.00 6.59   ? 597 GLY B O   1 
ATOM   3724 N N   . CYS B 2 87  ? 184.683 186.909 190.638 1.00 8.30   ? 598 CYS B N   1 
ATOM   3725 C CA  . CYS B 2 87  ? 183.352 187.501 190.531 1.00 8.14   ? 598 CYS B CA  1 
ATOM   3726 C C   . CYS B 2 87  ? 182.425 186.655 189.655 1.00 9.06   ? 598 CYS B C   1 
ATOM   3727 O O   . CYS B 2 87  ? 181.434 187.143 189.105 1.00 10.88  ? 598 CYS B O   1 
ATOM   3728 C CB  . CYS B 2 87  ? 183.470 188.932 189.957 1.00 7.58   ? 598 CYS B CB  1 
ATOM   3729 S SG  . CYS B 2 87  ? 184.402 190.088 190.992 1.00 6.94   ? 598 CYS B SG  1 
ATOM   3730 N N   . SER B 2 88  ? 182.761 185.395 189.483 1.00 10.43  ? 599 SER B N   1 
ATOM   3731 C CA  . SER B 2 88  ? 181.938 184.554 188.642 1.00 10.95  ? 599 SER B CA  1 
ATOM   3732 C C   . SER B 2 88  ? 180.545 184.391 189.203 1.00 13.29  ? 599 SER B C   1 
ATOM   3733 O O   . SER B 2 88  ? 180.368 184.145 190.396 1.00 14.90  ? 599 SER B O   1 
ATOM   3734 C CB  . SER B 2 88  ? 182.542 183.184 188.518 1.00 12.01  ? 599 SER B CB  1 
ATOM   3735 O OG  . SER B 2 88  ? 181.709 182.351 187.785 1.00 16.49  ? 599 SER B OG  1 
ATOM   3736 N N   . GLY B 2 89  ? 179.547 184.504 188.339 1.00 13.90  ? 600 GLY B N   1 
ATOM   3737 C CA  . GLY B 2 89  ? 178.172 184.271 188.741 1.00 8.87   ? 600 GLY B CA  1 
ATOM   3738 C C   . GLY B 2 89  ? 177.441 185.429 189.406 1.00 14.06  ? 600 GLY B C   1 
ATOM   3739 O O   . GLY B 2 89  ? 176.333 185.223 189.889 1.00 13.00  ? 600 GLY B O   1 
ATOM   3740 N N   . LYS B 2 90  ? 178.033 186.620 189.466 1.00 13.71  ? 601 LYS B N   1 
ATOM   3741 C CA  . LYS B 2 90  ? 177.357 187.739 190.129 1.00 8.89   ? 601 LYS B CA  1 
ATOM   3742 C C   . LYS B 2 90  ? 177.442 189.050 189.368 1.00 8.34   ? 601 LYS B C   1 
ATOM   3743 O O   . LYS B 2 90  ? 178.325 189.227 188.534 1.00 10.03  ? 601 LYS B O   1 
ATOM   3744 C CB  . LYS B 2 90  ? 177.863 187.839 191.551 1.00 10.05  ? 601 LYS B CB  1 
ATOM   3745 C CG  . LYS B 2 90  ? 179.340 187.958 191.687 1.00 10.31  ? 601 LYS B CG  1 
ATOM   3746 C CD  . LYS B 2 90  ? 179.760 188.019 193.138 1.00 10.24  ? 601 LYS B CD  1 
ATOM   3747 C CE  . LYS B 2 90  ? 179.589 186.680 193.830 1.00 13.38  ? 601 LYS B CE  1 
ATOM   3748 N NZ  . LYS B 2 90  ? 180.195 186.678 195.169 1.00 22.75  ? 601 LYS B NZ  1 
ATOM   3749 N N   . LEU B 2 91  ? 176.486 189.965 189.609 1.00 7.41   ? 602 LEU B N   1 
ATOM   3750 C CA  . LEU B 2 91  ? 176.490 191.240 188.912 1.00 6.14   ? 602 LEU B CA  1 
ATOM   3751 C C   . LEU B 2 91  ? 177.151 192.312 189.753 1.00 5.80   ? 602 LEU B C   1 
ATOM   3752 O O   . LEU B 2 91  ? 177.736 193.246 189.214 1.00 6.29   ? 602 LEU B O   1 
ATOM   3753 C CB  . LEU B 2 91  ? 175.063 191.612 188.515 1.00 6.48   ? 602 LEU B CB  1 
ATOM   3754 C CG  . LEU B 2 91  ? 174.337 190.608 187.568 1.00 7.92   ? 602 LEU B CG  1 
ATOM   3755 C CD1 . LEU B 2 91  ? 172.948 191.041 187.359 1.00 7.86   ? 602 LEU B CD1 1 
ATOM   3756 C CD2 . LEU B 2 91  ? 175.011 190.538 186.238 1.00 6.37   ? 602 LEU B CD2 1 
ATOM   3757 N N   . ILE B 2 92  ? 177.073 192.188 191.076 1.00 6.37   ? 603 ILE B N   1 
ATOM   3758 C CA  . ILE B 2 92  ? 177.774 193.119 191.966 1.00 4.76   ? 603 ILE B CA  1 
ATOM   3759 C C   . ILE B 2 92  ? 178.794 192.289 192.762 1.00 5.36   ? 603 ILE B C   1 
ATOM   3760 O O   . ILE B 2 92  ? 178.389 191.373 193.478 1.00 6.91   ? 603 ILE B O   1 
ATOM   3761 C CB  . ILE B 2 92  ? 176.838 193.834 192.954 1.00 4.53   ? 603 ILE B CB  1 
ATOM   3762 C CG1 . ILE B 2 92  ? 175.785 194.624 192.201 1.00 4.43   ? 603 ILE B CG1 1 
ATOM   3763 C CG2 . ILE B 2 92  ? 177.673 194.757 193.851 1.00 3.51   ? 603 ILE B CG2 1 
ATOM   3764 C CD1 . ILE B 2 92  ? 174.684 195.191 193.068 1.00 3.77   ? 603 ILE B CD1 1 
ATOM   3765 N N   . CYS B 2 93  ? 180.101 192.630 192.681 1.00 6.34   ? 604 CYS B N   1 
ATOM   3766 C CA  . CYS B 2 93  ? 181.200 191.903 193.327 1.00 4.48   ? 604 CYS B CA  1 
ATOM   3767 C C   . CYS B 2 93  ? 182.158 192.812 194.092 1.00 4.57   ? 604 CYS B C   1 
ATOM   3768 O O   . CYS B 2 93  ? 182.817 193.703 193.548 1.00 5.77   ? 604 CYS B O   1 
ATOM   3769 C CB  . CYS B 2 93  ? 181.939 191.101 192.234 1.00 5.98   ? 604 CYS B CB  1 
ATOM   3770 S SG  . CYS B 2 93  ? 183.337 190.118 192.714 1.00 9.27   ? 604 CYS B SG  1 
ATOM   3771 N N   . CYS B 2 94  ? 182.273 192.555 195.382 1.00 7.09   ? 605 CYS B N   1 
ATOM   3772 C CA  . CYS B 2 94  ? 183.156 193.326 196.231 1.00 4.98   ? 605 CYS B CA  1 
ATOM   3773 C C   . CYS B 2 94  ? 184.488 192.605 196.236 1.00 5.38   ? 605 CYS B C   1 
ATOM   3774 O O   . CYS B 2 94  ? 184.541 191.368 196.190 1.00 6.31   ? 605 CYS B O   1 
ATOM   3775 C CB  . CYS B 2 94  ? 182.565 193.520 197.646 1.00 5.21   ? 605 CYS B CB  1 
ATOM   3776 S SG  . CYS B 2 94  ? 181.001 194.500 197.643 1.00 9.14   ? 605 CYS B SG  1 
ATOM   3777 N N   . THR B 2 95  ? 185.568 193.374 196.298 1.00 6.14   ? 606 THR B N   1 
ATOM   3778 C CA  . THR B 2 95  ? 186.914 192.826 196.249 1.00 4.84   ? 606 THR B CA  1 
ATOM   3779 C C   . THR B 2 95  ? 187.747 193.322 197.410 1.00 4.89   ? 606 THR B C   1 
ATOM   3780 O O   . THR B 2 95  ? 187.248 194.042 198.274 1.00 5.37   ? 606 THR B O   1 
ATOM   3781 C CB  . THR B 2 95  ? 187.628 193.221 194.960 1.00 5.06   ? 606 THR B CB  1 
ATOM   3782 O OG1 . THR B 2 95  ? 188.039 194.579 195.036 1.00 5.98   ? 606 THR B OG1 1 
ATOM   3783 C CG2 . THR B 2 95  ? 186.674 193.055 193.766 1.00 4.80   ? 606 THR B CG2 1 
ATOM   3784 N N   . ASN B 2 96  ? 189.004 192.884 197.460 1.00 5.77   ? 607 ASN B N   1 
ATOM   3785 C CA  . ASN B 2 96  ? 189.966 193.317 198.468 1.00 5.13   ? 607 ASN B CA  1 
ATOM   3786 C C   . ASN B 2 96  ? 190.995 194.306 197.921 1.00 5.02   ? 607 ASN B C   1 
ATOM   3787 O O   . ASN B 2 96  ? 192.049 194.493 198.523 1.00 7.28   ? 607 ASN B O   1 
ATOM   3788 C CB  . ASN B 2 96  ? 190.688 192.145 199.089 1.00 4.82   ? 607 ASN B CB  1 
ATOM   3789 C CG  . ASN B 2 96  ? 189.837 191.316 199.959 1.00 4.77   ? 607 ASN B CG  1 
ATOM   3790 O OD1 . ASN B 2 96  ? 189.059 191.830 200.768 1.00 8.80   ? 607 ASN B OD1 1 
ATOM   3791 N ND2 . ASN B 2 96  ? 189.958 190.023 199.830 1.00 12.36  ? 607 ASN B ND2 1 
ATOM   3792 N N   . VAL B 2 97  ? 190.666 194.889 196.786 1.00 5.72   ? 608 VAL B N   1 
ATOM   3793 C CA  . VAL B 2 97  ? 191.533 195.888 196.122 1.00 5.13   ? 608 VAL B CA  1 
ATOM   3794 C C   . VAL B 2 97  ? 191.114 197.281 196.628 1.00 4.83   ? 608 VAL B C   1 
ATOM   3795 O O   . VAL B 2 97  ? 189.956 197.591 196.470 1.00 5.38   ? 608 VAL B O   1 
ATOM   3796 C CB  . VAL B 2 97  ? 191.661 195.718 194.596 1.00 4.89   ? 608 VAL B CB  1 
ATOM   3797 C CG1 . VAL B 2 97  ? 192.660 196.681 193.981 1.00 4.78   ? 608 VAL B CG1 1 
ATOM   3798 C CG2 . VAL B 2 97  ? 191.986 194.290 194.219 1.00 5.17   ? 608 VAL B CG2 1 
ATOM   3799 N N   . PRO B 2 98  ? 191.955 198.070 197.352 1.00 5.00   ? 609 PRO B N   1 
ATOM   3800 C CA  . PRO B 2 98  ? 191.594 199.386 197.817 1.00 4.13   ? 609 PRO B CA  1 
ATOM   3801 C C   . PRO B 2 98  ? 191.544 200.342 196.656 1.00 4.00   ? 609 PRO B C   1 
ATOM   3802 O O   . PRO B 2 98  ? 192.249 200.142 195.671 1.00 6.41   ? 609 PRO B O   1 
ATOM   3803 C CB  . PRO B 2 98  ? 192.702 199.704 198.800 1.00 3.76   ? 609 PRO B CB  1 
ATOM   3804 C CG  . PRO B 2 98  ? 193.858 198.919 198.331 1.00 3.96   ? 609 PRO B CG  1 
ATOM   3805 C CD  . PRO B 2 98  ? 193.288 197.663 197.744 1.00 5.51   ? 609 PRO B CD  1 
ATOM   3806 N N   . TRP B 2 99  ? 190.781 201.428 196.784 1.00 3.88   ? 610 TRP B N   1 
ATOM   3807 C CA  . TRP B 2 99  ? 190.795 202.496 195.748 1.00 3.75   ? 610 TRP B CA  1 
ATOM   3808 C C   . TRP B 2 99  ? 191.994 203.427 195.972 1.00 5.73   ? 610 TRP B C   1 
ATOM   3809 O O   . TRP B 2 99  ? 192.141 203.931 197.098 1.00 6.07   ? 610 TRP B O   1 
ATOM   3810 C CB  . TRP B 2 99  ? 189.468 203.264 195.752 1.00 3.13   ? 610 TRP B CB  1 
ATOM   3811 C CG  . TRP B 2 99  ? 189.258 204.124 194.544 1.00 2.92   ? 610 TRP B CG  1 
ATOM   3812 C CD1 . TRP B 2 99  ? 189.471 205.467 194.437 1.00 2.92   ? 610 TRP B CD1 1 
ATOM   3813 C CD2 . TRP B 2 99  ? 188.784 203.691 193.257 1.00 3.05   ? 610 TRP B CD2 1 
ATOM   3814 N NE1 . TRP B 2 99  ? 189.171 205.897 193.174 1.00 3.59   ? 610 TRP B NE1 1 
ATOM   3815 C CE2 . TRP B 2 99  ? 188.745 204.830 192.427 1.00 2.70   ? 610 TRP B CE2 1 
ATOM   3816 C CE3 . TRP B 2 99  ? 188.393 202.457 192.726 1.00 2.63   ? 610 TRP B CE3 1 
ATOM   3817 C CZ2 . TRP B 2 99  ? 188.332 204.767 191.099 1.00 2.98   ? 610 TRP B CZ2 1 
ATOM   3818 C CZ3 . TRP B 2 99  ? 187.984 202.394 191.414 1.00 2.11   ? 610 TRP B CZ3 1 
ATOM   3819 C CH2 . TRP B 2 99  ? 187.954 203.537 190.614 1.00 2.60   ? 610 TRP B CH2 1 
ATOM   3820 N N   . ASN B 2 100 ? 192.794 203.710 194.936 1.00 5.79   ? 611 ASN B N   1 
ATOM   3821 C CA  . ASN B 2 100 ? 193.812 204.785 194.890 1.00 6.00   ? 611 ASN B CA  1 
ATOM   3822 C C   . ASN B 2 100 ? 193.089 206.053 194.504 1.00 6.74   ? 611 ASN B C   1 
ATOM   3823 O O   . ASN B 2 100 ? 192.422 206.038 193.510 1.00 9.36   ? 611 ASN B O   1 
ATOM   3824 C CB  . ASN B 2 100 ? 194.967 204.522 193.925 1.00 7.96   ? 611 ASN B CB  1 
ATOM   3825 C CG  . ASN B 2 100 ? 196.295 205.109 194.330 1.00 17.15  ? 611 ASN B CG  1 
ATOM   3826 O OD1 . ASN B 2 100 ? 196.371 205.990 195.177 1.00 0.03   ? 611 ASN B OD1 1 
ATOM   3827 N ND2 . ASN B 2 100 ? 197.353 204.620 193.717 1.00 15.30  ? 611 ASN B ND2 1 
ATOM   3828 N N   . SER B 2 101 ? 193.261 207.110 195.275 1.00 8.32   ? 612 SER B N   1 
ATOM   3829 C CA  . SER B 2 101 ? 192.602 208.399 194.940 1.00 8.00   ? 612 SER B CA  1 
ATOM   3830 C C   . SER B 2 101 ? 193.337 209.077 193.778 1.00 9.21   ? 612 SER B C   1 
ATOM   3831 O O   . SER B 2 101 ? 192.845 210.102 193.275 1.00 11.88  ? 612 SER B O   1 
ATOM   3832 C CB  . SER B 2 101 ? 192.535 209.294 196.142 1.00 8.91   ? 612 SER B CB  1 
ATOM   3833 O OG  . SER B 2 101 ? 193.833 209.534 196.658 1.00 49.88  ? 612 SER B OG  1 
ATOM   3834 N N   . SER B 2 102 ? 194.435 208.514 193.297 1.00 9.78   ? 613 SER B N   1 
ATOM   3835 C CA  . SER B 2 102 ? 195.162 208.959 192.091 1.00 9.13   ? 613 SER B CA  1 
ATOM   3836 C C   . SER B 2 102 ? 194.372 208.595 190.840 1.00 8.88   ? 613 SER B C   1 
ATOM   3837 O O   . SER B 2 102 ? 194.601 209.193 189.805 1.00 11.95  ? 613 SER B O   1 
ATOM   3838 C CB  . SER B 2 102 ? 196.477 208.309 192.072 1.00 12.85  ? 613 SER B CB  1 
ATOM   3839 O OG  . SER B 2 102 ? 196.389 207.023 191.490 1.00 16.39  ? 613 SER B OG  1 
ATOM   3840 N N   . TRP B 2 103 ? 193.447 207.668 190.989 1.00 9.57   ? 614 TRP B N   1 
ATOM   3841 C CA  . TRP B 2 103 ? 192.544 207.116 189.974 1.00 7.51   ? 614 TRP B CA  1 
ATOM   3842 C C   . TRP B 2 103 ? 191.340 208.027 189.897 1.00 8.56   ? 614 TRP B C   1 
ATOM   3843 O O   . TRP B 2 103 ? 190.873 208.305 188.800 1.00 11.41  ? 614 TRP B O   1 
ATOM   3844 C CB  . TRP B 2 103 ? 192.098 205.736 190.408 1.00 7.50   ? 614 TRP B CB  1 
ATOM   3845 C CG  . TRP B 2 103 ? 193.140 204.666 190.432 1.00 7.34   ? 614 TRP B CG  1 
ATOM   3846 C CD1 . TRP B 2 103 ? 194.379 204.682 189.869 1.00 7.95   ? 614 TRP B CD1 1 
ATOM   3847 C CD2 . TRP B 2 103 ? 192.992 203.379 191.049 1.00 6.71   ? 614 TRP B CD2 1 
ATOM   3848 N NE1 . TRP B 2 103 ? 195.016 203.498 190.107 1.00 8.40   ? 614 TRP B NE1 1 
ATOM   3849 C CE2 . TRP B 2 103 ? 194.191 202.677 190.824 1.00 7.73   ? 614 TRP B CE2 1 
ATOM   3850 C CE3 . TRP B 2 103 ? 191.966 202.761 191.768 1.00 5.36   ? 614 TRP B CE3 1 
ATOM   3851 C CZ2 . TRP B 2 103 ? 194.389 201.385 191.304 1.00 8.90   ? 614 TRP B CZ2 1 
ATOM   3852 C CZ3 . TRP B 2 103 ? 192.162 201.487 192.239 1.00 5.12   ? 614 TRP B CZ3 1 
ATOM   3853 C CH2 . TRP B 2 103 ? 193.356 200.809 192.006 1.00 6.99   ? 614 TRP B CH2 1 
ATOM   3854 N N   . SER B 2 104 ? 190.845 208.420 191.065 1.00 8.69   ? 615 SER B N   1 
ATOM   3855 C CA  . SER B 2 104 ? 189.765 209.397 191.210 1.00 8.11   ? 615 SER B CA  1 
ATOM   3856 C C   . SER B 2 104 ? 189.677 209.817 192.644 1.00 8.47   ? 615 SER B C   1 
ATOM   3857 O O   . SER B 2 104 ? 189.549 208.969 193.528 1.00 10.43  ? 615 SER B O   1 
ATOM   3858 C CB  . SER B 2 104 ? 188.415 208.887 190.799 1.00 8.03   ? 615 SER B CB  1 
ATOM   3859 O OG  . SER B 2 104 ? 187.450 209.900 191.003 1.00 12.51  ? 615 SER B OG  1 
ATOM   3860 N N   . ASN B 2 105 ? 189.666 211.116 192.894 1.00 11.72  ? 616 ASN B N   1 
ATOM   3861 C CA  . ASN B 2 105 ? 189.575 211.618 194.249 1.00 12.02  ? 616 ASN B CA  1 
ATOM   3862 C C   . ASN B 2 105 ? 188.216 212.184 194.589 1.00 13.71  ? 616 ASN B C   1 
ATOM   3863 O O   . ASN B 2 105 ? 188.100 212.972 195.525 1.00 16.22  ? 616 ASN B O   1 
ATOM   3864 C CB  . ASN B 2 105 ? 190.648 212.643 194.497 1.00 14.26  ? 616 ASN B CB  1 
ATOM   3865 C CG  . ASN B 2 105 ? 190.492 213.818 193.627 1.00 18.88  ? 616 ASN B CG  1 
ATOM   3866 O OD1 . ASN B 2 105 ? 189.893 213.721 192.540 1.00 18.51  ? 616 ASN B OD1 1 
ATOM   3867 N ND2 . ASN B 2 105 ? 191.017 214.940 194.051 1.00 23.16  ? 616 ASN B ND2 1 
ATOM   3868 N N   . ARG B 2 106 ? 187.197 211.793 193.836 1.00 14.25  ? 617 ARG B N   1 
ATOM   3869 C CA  . ARG B 2 106 ? 185.842 212.226 194.125 1.00 11.54  ? 617 ARG B CA  1 
ATOM   3870 C C   . ARG B 2 106 ? 185.297 211.383 195.272 1.00 12.45  ? 617 ARG B C   1 
ATOM   3871 O O   . ARG B 2 106 ? 185.697 210.221 195.396 1.00 12.92  ? 617 ARG B O   1 
ATOM   3872 C CB  . ARG B 2 106 ? 184.951 212.052 192.924 1.00 12.57  ? 617 ARG B CB  1 
ATOM   3873 C CG  . ARG B 2 106 ? 185.229 212.907 191.759 1.00 15.70  ? 617 ARG B CG  1 
ATOM   3874 C CD  . ARG B 2 106 ? 184.162 212.716 190.787 1.00 14.99  ? 617 ARG B CD  1 
ATOM   3875 N NE  . ARG B 2 106 ? 184.344 213.437 189.570 1.00 19.45  ? 617 ARG B NE  1 
ATOM   3876 C CZ  . ARG B 2 106 ? 183.995 214.720 189.323 1.00 21.06  ? 617 ARG B CZ  1 
ATOM   3877 N NH1 . ARG B 2 106 ? 183.471 215.504 190.255 1.00 20.20  ? 617 ARG B NH1 1 
ATOM   3878 N NH2 . ARG B 2 106 ? 184.180 215.208 188.108 1.00 22.98  ? 617 ARG B NH2 1 
ATOM   3879 N N   . ASN B 2 107 ? 184.371 211.934 196.104 1.00 12.12  ? 618 ASN B N   1 
ATOM   3880 C CA  . ASN B 2 107 ? 183.721 211.176 197.180 1.00 10.30  ? 618 ASN B CA  1 
ATOM   3881 C C   . ASN B 2 107 ? 182.481 210.434 196.654 1.00 8.55   ? 618 ASN B C   1 
ATOM   3882 O O   . ASN B 2 107 ? 182.146 210.526 195.469 1.00 11.19  ? 618 ASN B O   1 
ATOM   3883 C CB  . ASN B 2 107 ? 183.430 212.079 198.400 1.00 13.39  ? 618 ASN B CB  1 
ATOM   3884 C CG  . ASN B 2 107 ? 182.393 213.239 198.208 1.00 15.18  ? 618 ASN B CG  1 
ATOM   3885 O OD1 . ASN B 2 107 ? 181.539 213.242 197.293 1.00 15.27  ? 618 ASN B OD1 1 
ATOM   3886 N ND2 . ASN B 2 107 ? 182.496 214.228 199.109 1.00 23.43  ? 618 ASN B ND2 1 
ATOM   3887 N N   . LEU B 2 108 ? 181.790 209.671 197.535 1.00 9.34   ? 619 LEU B N   1 
ATOM   3888 C CA  . LEU B 2 108 ? 180.635 208.841 197.178 1.00 6.70   ? 619 LEU B CA  1 
ATOM   3889 C C   . LEU B 2 108 ? 179.431 209.637 196.715 1.00 6.60   ? 619 LEU B C   1 
ATOM   3890 O O   . LEU B 2 108 ? 178.679 209.179 195.865 1.00 7.56   ? 619 LEU B O   1 
ATOM   3891 C CB  . LEU B 2 108 ? 180.271 207.964 198.364 1.00 5.05   ? 619 LEU B CB  1 
ATOM   3892 C CG  . LEU B 2 108 ? 181.295 206.881 198.728 1.00 2.72   ? 619 LEU B CG  1 
ATOM   3893 C CD1 . LEU B 2 108 ? 180.914 206.285 199.984 1.00 3.08   ? 619 LEU B CD1 1 
ATOM   3894 C CD2 . LEU B 2 108 ? 181.337 205.785 197.691 1.00 2.87   ? 619 LEU B CD2 1 
ATOM   3895 N N   . SER B 2 109 ? 179.252 210.835 197.204 1.00 10.16  ? 620 SER B N   1 
ATOM   3896 C CA  . SER B 2 109 ? 178.072 211.601 196.774 1.00 8.92   ? 620 SER B CA  1 
ATOM   3897 C C   . SER B 2 109 ? 178.322 212.143 195.376 1.00 9.50   ? 620 SER B C   1 
ATOM   3898 O O   . SER B 2 109 ? 177.382 212.200 194.608 1.00 12.55  ? 620 SER B O   1 
ATOM   3899 C CB  . SER B 2 109 ? 177.807 212.653 197.746 1.00 12.22  ? 620 SER B CB  1 
ATOM   3900 O OG  . SER B 2 109 ? 178.461 212.373 198.968 1.00 15.93  ? 620 SER B OG  1 
ATOM   3901 N N   . GLU B 2 110 ? 179.572 212.476 195.064 1.00 10.41  ? 621 GLU B N   1 
ATOM   3902 C CA  . GLU B 2 110 ? 179.917 212.910 193.721 1.00 8.69   ? 621 GLU B CA  1 
ATOM   3903 C C   . GLU B 2 110 ? 179.794 211.803 192.697 1.00 6.98   ? 621 GLU B C   1 
ATOM   3904 O O   . GLU B 2 110 ? 179.419 212.059 191.558 1.00 9.10   ? 621 GLU B O   1 
ATOM   3905 C CB  . GLU B 2 110 ? 181.341 213.401 193.655 1.00 11.32  ? 621 GLU B CB  1 
ATOM   3906 C CG  . GLU B 2 110 ? 181.648 214.694 194.289 1.00 15.92  ? 621 GLU B CG  1 
ATOM   3907 C CD  . GLU B 2 110 ? 183.102 214.982 194.276 1.00 18.50  ? 621 GLU B CD  1 
ATOM   3908 O OE1 . GLU B 2 110 ? 183.768 214.684 195.247 1.00 19.37  ? 621 GLU B OE1 1 
ATOM   3909 O OE2 . GLU B 2 110 ? 183.587 215.423 193.263 1.00 20.87  ? 621 GLU B OE2 1 
ATOM   3910 N N   . ILE B 2 111 ? 180.140 210.586 193.089 1.00 8.07   ? 622 ILE B N   1 
ATOM   3911 C CA  . ILE B 2 111 ? 180.118 209.461 192.179 1.00 5.87   ? 622 ILE B CA  1 
ATOM   3912 C C   . ILE B 2 111 ? 178.778 208.757 192.079 1.00 4.64   ? 622 ILE B C   1 
ATOM   3913 O O   . ILE B 2 111 ? 178.350 208.443 190.984 1.00 5.28   ? 622 ILE B O   1 
ATOM   3914 C CB  . ILE B 2 111 ? 181.187 208.430 192.588 1.00 5.14   ? 622 ILE B CB  1 
ATOM   3915 C CG1 . ILE B 2 111 ? 182.540 209.077 192.455 1.00 6.87   ? 622 ILE B CG1 1 
ATOM   3916 C CG2 . ILE B 2 111 ? 181.102 207.156 191.702 1.00 3.89   ? 622 ILE B CG2 1 
ATOM   3917 C CD1 . ILE B 2 111 ? 183.646 208.310 193.079 1.00 7.27   ? 622 ILE B CD1 1 
ATOM   3918 N N   . TRP B 2 112 ? 177.999 208.617 193.117 1.00 6.43   ? 623 TRP B N   1 
ATOM   3919 C CA  . TRP B 2 112 ? 176.851 207.687 193.021 1.00 4.85   ? 623 TRP B CA  1 
ATOM   3920 C C   . TRP B 2 112 ? 175.553 208.452 192.894 1.00 6.35   ? 623 TRP B C   1 
ATOM   3921 O O   . TRP B 2 112 ? 174.591 207.899 192.412 1.00 6.97   ? 623 TRP B O   1 
ATOM   3922 C CB  . TRP B 2 112 ? 176.834 206.685 194.183 1.00 4.41   ? 623 TRP B CB  1 
ATOM   3923 C CG  . TRP B 2 112 ? 177.949 205.694 194.138 1.00 3.04   ? 623 TRP B CG  1 
ATOM   3924 C CD1 . TRP B 2 112 ? 179.107 205.717 194.852 1.00 3.02   ? 623 TRP B CD1 1 
ATOM   3925 C CD2 . TRP B 2 112 ? 178.019 204.542 193.290 1.00 3.03   ? 623 TRP B CD2 1 
ATOM   3926 N NE1 . TRP B 2 112 ? 179.889 204.650 194.514 1.00 2.87   ? 623 TRP B NE1 1 
ATOM   3927 C CE2 . TRP B 2 112 ? 179.247 203.913 193.557 1.00 2.96   ? 623 TRP B CE2 1 
ATOM   3928 C CE3 . TRP B 2 112 ? 177.157 203.976 192.351 1.00 3.09   ? 623 TRP B CE3 1 
ATOM   3929 C CZ2 . TRP B 2 112 ? 179.628 202.746 192.905 1.00 3.47   ? 623 TRP B CZ2 1 
ATOM   3930 C CZ3 . TRP B 2 112 ? 177.535 202.829 191.700 1.00 2.63   ? 623 TRP B CZ3 1 
ATOM   3931 C CH2 . TRP B 2 112 ? 178.757 202.230 191.976 1.00 3.06   ? 623 TRP B CH2 1 
ATOM   3932 N N   . ASP B 2 113 ? 175.574 209.698 193.340 1.00 8.62   ? 624 ASP B N   1 
ATOM   3933 C CA  . ASP B 2 113 ? 174.435 210.635 193.297 1.00 9.40   ? 624 ASP B CA  1 
ATOM   3934 C C   . ASP B 2 113 ? 174.599 211.700 192.198 1.00 11.22  ? 624 ASP B C   1 
ATOM   3935 O O   . ASP B 2 113 ? 173.628 212.415 191.996 1.00 12.82  ? 624 ASP B O   1 
ATOM   3936 C CB  . ASP B 2 113 ? 174.138 211.115 194.709 1.00 12.42  ? 624 ASP B CB  1 
ATOM   3937 C CG  . ASP B 2 113 ? 173.726 210.014 195.664 1.00 13.56  ? 624 ASP B CG  1 
ATOM   3938 O OD1 . ASP B 2 113 ? 172.967 209.128 195.240 1.00 18.66  ? 624 ASP B OD1 1 
ATOM   3939 O OD2 . ASP B 2 113 ? 174.145 210.066 196.829 1.00 15.30  ? 624 ASP B OD2 1 
ATOM   3940 N N   . ASN B 2 114 ? 175.727 211.767 191.483 1.00 9.50   ? 625 ASN B N   1 
ATOM   3941 C CA  . ASN B 2 114 ? 175.898 212.457 190.173 1.00 9.87   ? 625 ASN B CA  1 
ATOM   3942 C C   . ASN B 2 114 ? 176.533 211.551 189.086 1.00 8.58   ? 625 ASN B C   1 
ATOM   3943 O O   . ASN B 2 114 ? 175.959 210.494 188.808 1.00 11.59  ? 625 ASN B O   1 
ATOM   3944 C CB  . ASN B 2 114 ? 176.649 213.760 190.371 1.00 15.90  ? 625 ASN B CB  1 
ATOM   3945 C CG  . ASN B 2 114 ? 176.083 214.683 191.432 1.00 26.42  ? 625 ASN B CG  1 
ATOM   3946 O OD1 . ASN B 2 114 ? 175.286 215.567 191.132 1.00 28.18  ? 625 ASN B OD1 1 
ATOM   3947 N ND2 . ASN B 2 114 ? 176.499 214.504 192.674 1.00 27.12  ? 625 ASN B ND2 1 
ATOM   3948 N N   . MET B 2 115 ? 177.677 211.936 188.497 1.00 7.20   ? 626 MET B N   1 
ATOM   3949 C CA  . MET B 2 115 ? 178.426 211.238 187.428 1.00 6.22   ? 626 MET B CA  1 
ATOM   3950 C C   . MET B 2 115 ? 177.700 209.939 187.051 1.00 5.07   ? 626 MET B C   1 
ATOM   3951 O O   . MET B 2 115 ? 178.037 208.991 187.716 1.00 6.42   ? 626 MET B O   1 
ATOM   3952 C CB  . MET B 2 115 ? 179.799 210.869 188.001 1.00 6.74   ? 626 MET B CB  1 
ATOM   3953 C CG  . MET B 2 115 ? 180.908 210.813 186.983 1.00 6.71   ? 626 MET B CG  1 
ATOM   3954 S SD  . MET B 2 115 ? 182.096 212.160 187.165 1.00 9.99   ? 626 MET B SD  1 
ATOM   3955 C CE  . MET B 2 115 ? 181.198 213.522 186.424 1.00 10.93  ? 626 MET B CE  1 
ATOM   3956 N N   . THR B 2 116 ? 176.700 209.897 186.128 1.00 5.33   ? 627 THR B N   1 
ATOM   3957 C CA  . THR B 2 116 ? 176.197 208.741 185.378 1.00 4.92   ? 627 THR B CA  1 
ATOM   3958 C C   . THR B 2 116 ? 177.345 207.785 185.062 1.00 4.67   ? 627 THR B C   1 
ATOM   3959 O O   . THR B 2 116 ? 178.512 208.160 185.166 1.00 7.22   ? 627 THR B O   1 
ATOM   3960 C CB  . THR B 2 116 ? 175.564 209.169 184.050 1.00 5.69   ? 627 THR B CB  1 
ATOM   3961 O OG1 . THR B 2 116 ? 176.581 209.645 183.160 1.00 7.20   ? 627 THR B OG1 1 
ATOM   3962 C CG2 . THR B 2 116 ? 174.602 210.298 184.305 1.00 6.35   ? 627 THR B CG2 1 
ATOM   3963 N N   . TRP B 2 117 ? 177.041 206.563 184.615 1.00 4.78   ? 628 TRP B N   1 
ATOM   3964 C CA  . TRP B 2 117 ? 178.109 205.621 184.279 1.00 4.66   ? 628 TRP B CA  1 
ATOM   3965 C C   . TRP B 2 117 ? 178.884 206.007 183.028 1.00 5.67   ? 628 TRP B C   1 
ATOM   3966 O O   . TRP B 2 117 ? 180.054 205.658 182.903 1.00 6.75   ? 628 TRP B O   1 
ATOM   3967 C CB  . TRP B 2 117 ? 177.578 204.203 184.121 1.00 5.22   ? 628 TRP B CB  1 
ATOM   3968 C CG  . TRP B 2 117 ? 177.329 203.457 185.380 1.00 3.83   ? 628 TRP B CG  1 
ATOM   3969 C CD1 . TRP B 2 117 ? 176.158 203.234 185.955 1.00 3.82   ? 628 TRP B CD1 1 
ATOM   3970 C CD2 . TRP B 2 117 ? 178.300 202.767 186.187 1.00 4.34   ? 628 TRP B CD2 1 
ATOM   3971 N NE1 . TRP B 2 117 ? 176.316 202.485 187.079 1.00 4.13   ? 628 TRP B NE1 1 
ATOM   3972 C CE2 . TRP B 2 117 ? 177.619 202.189 187.227 1.00 3.98   ? 628 TRP B CE2 1 
ATOM   3973 C CE3 . TRP B 2 117 ? 179.675 202.591 186.096 1.00 4.16   ? 628 TRP B CE3 1 
ATOM   3974 C CZ2 . TRP B 2 117 ? 178.254 201.452 188.187 1.00 3.50   ? 628 TRP B CZ2 1 
ATOM   3975 C CZ3 . TRP B 2 117 ? 180.308 201.844 187.057 1.00 3.59   ? 628 TRP B CZ3 1 
ATOM   3976 C CH2 . TRP B 2 117 ? 179.619 201.297 188.069 1.00 2.77   ? 628 TRP B CH2 1 
ATOM   3977 N N   . LEU B 2 118 ? 178.256 206.718 182.093 1.00 6.64   ? 629 LEU B N   1 
ATOM   3978 C CA  . LEU B 2 118 ? 178.958 207.160 180.893 1.00 5.51   ? 629 LEU B CA  1 
ATOM   3979 C C   . LEU B 2 118 ? 180.014 208.193 181.266 1.00 6.60   ? 629 LEU B C   1 
ATOM   3980 O O   . LEU B 2 118 ? 181.113 208.200 180.704 1.00 10.62  ? 629 LEU B O   1 
ATOM   3981 C CB  . LEU B 2 118 ? 177.954 207.760 179.893 1.00 6.71   ? 629 LEU B CB  1 
ATOM   3982 C CG  . LEU B 2 118 ? 176.954 206.773 179.185 1.00 6.31   ? 629 LEU B CG  1 
ATOM   3983 C CD1 . LEU B 2 118 ? 175.837 207.552 178.509 1.00 6.98   ? 629 LEU B CD1 1 
ATOM   3984 C CD2 . LEU B 2 118 ? 177.678 205.986 178.113 1.00 5.26   ? 629 LEU B CD2 1 
ATOM   3985 N N   . GLN B 2 119 ? 179.683 209.076 182.211 1.00 6.98   ? 630 GLN B N   1 
ATOM   3986 C CA  . GLN B 2 119 ? 180.616 210.101 182.651 1.00 5.90   ? 630 GLN B CA  1 
ATOM   3987 C C   . GLN B 2 119 ? 181.764 209.505 183.435 1.00 7.52   ? 630 GLN B C   1 
ATOM   3988 O O   . GLN B 2 119 ? 182.921 209.875 183.227 1.00 10.49  ? 630 GLN B O   1 
ATOM   3989 C CB  . GLN B 2 119 ? 179.890 211.102 183.526 1.00 6.66   ? 630 GLN B CB  1 
ATOM   3990 C CG  . GLN B 2 119 ? 178.917 211.955 182.803 1.00 6.42   ? 630 GLN B CG  1 
ATOM   3991 C CD  . GLN B 2 119 ? 178.105 212.778 183.735 1.00 5.89   ? 630 GLN B CD  1 
ATOM   3992 O OE1 . GLN B 2 119 ? 177.666 212.325 184.799 1.00 8.42   ? 630 GLN B OE1 1 
ATOM   3993 N NE2 . GLN B 2 119 ? 177.879 214.019 183.362 1.00 0.00   ? 630 GLN B NE2 1 
ATOM   3994 N N   . TRP B 2 120 ? 181.448 208.549 184.300 1.00 7.56   ? 631 TRP B N   1 
ATOM   3995 C CA  . TRP B 2 120 ? 182.440 207.870 185.099 1.00 5.97   ? 631 TRP B CA  1 
ATOM   3996 C C   . TRP B 2 120 ? 183.395 207.102 184.224 1.00 6.82   ? 631 TRP B C   1 
ATOM   3997 O O   . TRP B 2 120 ? 184.610 207.164 184.405 1.00 10.76  ? 631 TRP B O   1 
ATOM   3998 C CB  . TRP B 2 120 ? 181.767 206.956 186.085 1.00 5.41   ? 631 TRP B CB  1 
ATOM   3999 C CG  . TRP B 2 120 ? 182.671 206.191 186.937 1.00 4.68   ? 631 TRP B CG  1 
ATOM   4000 C CD1 . TRP B 2 120 ? 182.827 204.883 186.893 1.00 3.63   ? 631 TRP B CD1 1 
ATOM   4001 C CD2 . TRP B 2 120 ? 183.552 206.648 187.965 1.00 3.96   ? 631 TRP B CD2 1 
ATOM   4002 N NE1 . TRP B 2 120 ? 183.703 204.495 187.808 1.00 3.48   ? 631 TRP B NE1 1 
ATOM   4003 C CE2 . TRP B 2 120 ? 184.156 205.552 188.470 1.00 3.58   ? 631 TRP B CE2 1 
ATOM   4004 C CE3 . TRP B 2 120 ? 183.862 207.877 188.482 1.00 5.69   ? 631 TRP B CE3 1 
ATOM   4005 C CZ2 . TRP B 2 120 ? 185.046 205.623 189.463 1.00 3.62   ? 631 TRP B CZ2 1 
ATOM   4006 C CZ3 . TRP B 2 120 ? 184.760 207.949 189.484 1.00 6.42   ? 631 TRP B CZ3 1 
ATOM   4007 C CH2 . TRP B 2 120 ? 185.337 206.842 189.966 1.00 4.35   ? 631 TRP B CH2 1 
ATOM   4008 N N   . ASP B 2 121 ? 182.869 206.393 183.233 1.00 8.57   ? 632 ASP B N   1 
ATOM   4009 C CA  . ASP B 2 121 ? 183.730 205.628 182.372 1.00 8.52   ? 632 ASP B CA  1 
ATOM   4010 C C   . ASP B 2 121 ? 184.751 206.523 181.711 1.00 11.23  ? 632 ASP B C   1 
ATOM   4011 O O   . ASP B 2 121 ? 185.919 206.159 181.628 1.00 15.74  ? 632 ASP B O   1 
ATOM   4012 C CB  . ASP B 2 121 ? 182.912 204.911 181.313 1.00 9.99   ? 632 ASP B CB  1 
ATOM   4013 C CG  . ASP B 2 121 ? 183.741 204.014 180.422 1.00 17.50  ? 632 ASP B CG  1 
ATOM   4014 O OD1 . ASP B 2 121 ? 184.235 203.018 180.878 1.00 22.17  ? 632 ASP B OD1 1 
ATOM   4015 O OD2 . ASP B 2 121 ? 183.874 204.337 179.255 1.00 19.79  ? 632 ASP B OD2 1 
ATOM   4016 N N   . LYS B 2 122 ? 184.394 207.719 181.270 1.00 13.03  ? 633 LYS B N   1 
ATOM   4017 C CA  . LYS B 2 122 ? 185.355 208.636 180.602 1.00 11.37  ? 633 LYS B CA  1 
ATOM   4018 C C   . LYS B 2 122 ? 186.482 209.047 181.542 1.00 11.83  ? 633 LYS B C   1 
ATOM   4019 O O   . LYS B 2 122 ? 187.628 209.064 181.121 1.00 14.09  ? 633 LYS B O   1 
ATOM   4020 C CB  . LYS B 2 122 ? 184.628 209.879 180.101 1.00 13.61  ? 633 LYS B CB  1 
ATOM   4021 C CG  . LYS B 2 122 ? 183.808 209.691 178.834 1.00 18.04  ? 633 LYS B CG  1 
ATOM   4022 C CD  . LYS B 2 122 ? 182.745 210.751 178.652 1.00 23.38  ? 633 LYS B CD  1 
ATOM   4023 C CE  . LYS B 2 122 ? 181.560 210.262 177.847 1.00 37.19  ? 633 LYS B CE  1 
ATOM   4024 N NZ  . LYS B 2 122 ? 180.327 211.026 178.153 1.00 48.23  ? 633 LYS B NZ  1 
ATOM   4025 N N   . GLU B 2 123 ? 186.134 209.383 182.767 1.00 13.08  ? 634 GLU B N   1 
ATOM   4026 C CA  . GLU B 2 123 ? 186.997 209.937 183.824 1.00 11.91  ? 634 GLU B CA  1 
ATOM   4027 C C   . GLU B 2 123 ? 188.044 208.908 184.226 1.00 13.21  ? 634 GLU B C   1 
ATOM   4028 O O   . GLU B 2 123 ? 189.211 209.286 184.341 1.00 15.26  ? 634 GLU B O   1 
ATOM   4029 C CB  . GLU B 2 123 ? 186.118 210.335 185.000 1.00 13.02  ? 634 GLU B CB  1 
ATOM   4030 C CG  . GLU B 2 123 ? 186.827 210.401 186.332 1.00 17.81  ? 634 GLU B CG  1 
ATOM   4031 C CD  . GLU B 2 123 ? 186.264 211.468 187.249 1.00 18.20  ? 634 GLU B CD  1 
ATOM   4032 O OE1 . GLU B 2 123 ? 185.437 212.267 186.770 1.00 18.75  ? 634 GLU B OE1 1 
ATOM   4033 O OE2 . GLU B 2 123 ? 186.661 211.501 188.429 1.00 18.34  ? 634 GLU B OE2 1 
ATOM   4034 N N   . ILE B 2 124 ? 187.673 207.646 184.408 1.00 13.14  ? 635 ILE B N   1 
ATOM   4035 C CA  . ILE B 2 124 ? 188.733 206.723 184.790 1.00 12.26  ? 635 ILE B CA  1 
ATOM   4036 C C   . ILE B 2 124 ? 189.197 205.816 183.671 1.00 11.24  ? 635 ILE B C   1 
ATOM   4037 O O   . ILE B 2 124 ? 189.802 204.779 183.940 1.00 13.26  ? 635 ILE B O   1 
ATOM   4038 C CB  . ILE B 2 124 ? 188.360 205.836 185.994 1.00 10.59  ? 635 ILE B CB  1 
ATOM   4039 C CG1 . ILE B 2 124 ? 187.140 204.981 185.683 1.00 8.50   ? 635 ILE B CG1 1 
ATOM   4040 C CG2 . ILE B 2 124 ? 188.115 206.746 187.206 1.00 9.16   ? 635 ILE B CG2 1 
ATOM   4041 C CD1 . ILE B 2 124 ? 186.919 203.870 186.673 1.00 8.21   ? 635 ILE B CD1 1 
ATOM   4042 N N   . SER B 2 125 ? 188.886 206.050 182.414 1.00 13.89  ? 636 SER B N   1 
ATOM   4043 C CA  . SER B 2 125 ? 189.319 205.146 181.309 1.00 12.86  ? 636 SER B CA  1 
ATOM   4044 C C   . SER B 2 125 ? 190.818 204.846 181.314 1.00 14.67  ? 636 SER B C   1 
ATOM   4045 O O   . SER B 2 125 ? 191.194 203.760 180.877 1.00 15.05  ? 636 SER B O   1 
ATOM   4046 C CB  . SER B 2 125 ? 188.971 205.770 180.021 1.00 14.74  ? 636 SER B CB  1 
ATOM   4047 O OG  . SER B 2 125 ? 189.489 207.088 179.952 1.00 16.94  ? 636 SER B OG  1 
ATOM   4048 N N   . ASN B 2 126 ? 191.636 205.796 181.758 1.00 15.80  ? 637 ASN B N   1 
ATOM   4049 C CA  . ASN B 2 126 ? 193.115 205.746 181.740 1.00 13.94  ? 637 ASN B CA  1 
ATOM   4050 C C   . ASN B 2 126 ? 193.682 204.788 182.774 1.00 14.95  ? 637 ASN B C   1 
ATOM   4051 O O   . ASN B 2 126 ? 194.893 204.648 182.798 1.00 16.57  ? 637 ASN B O   1 
ATOM   4052 C CB  . ASN B 2 126 ? 193.698 207.057 182.229 1.00 19.73  ? 637 ASN B CB  1 
ATOM   4053 C CG  . ASN B 2 126 ? 193.647 208.197 181.240 1.00 28.23  ? 637 ASN B CG  1 
ATOM   4054 O OD1 . ASN B 2 126 ? 193.406 207.995 180.054 1.00 30.03  ? 637 ASN B OD1 1 
ATOM   4055 N ND2 . ASN B 2 126 ? 193.889 209.397 181.740 1.00 36.68  ? 637 ASN B ND2 1 
ATOM   4056 N N   . TYR B 2 127 ? 192.844 204.217 183.635 1.00 14.35  ? 638 TYR B N   1 
ATOM   4057 C CA  . TYR B 2 127 ? 193.271 203.515 184.866 1.00 9.69   ? 638 TYR B CA  1 
ATOM   4058 C C   . TYR B 2 127 ? 192.691 202.111 184.875 1.00 8.91   ? 638 TYR B C   1 
ATOM   4059 O O   . TYR B 2 127 ? 193.081 201.428 185.763 1.00 12.55  ? 638 TYR B O   1 
ATOM   4060 C CB  . TYR B 2 127 ? 192.843 204.286 186.109 1.00 10.23  ? 638 TYR B CB  1 
ATOM   4061 C CG  . TYR B 2 127 ? 193.302 205.715 186.197 1.00 11.00  ? 638 TYR B CG  1 
ATOM   4062 C CD1 . TYR B 2 127 ? 194.626 206.026 186.437 1.00 14.18  ? 638 TYR B CD1 1 
ATOM   4063 C CD2 . TYR B 2 127 ? 192.407 206.755 186.040 1.00 12.07  ? 638 TYR B CD2 1 
ATOM   4064 C CE1 . TYR B 2 127 ? 195.051 207.339 186.515 1.00 14.14  ? 638 TYR B CE1 1 
ATOM   4065 C CE2 . TYR B 2 127 ? 192.815 208.073 186.107 1.00 11.98  ? 638 TYR B CE2 1 
ATOM   4066 C CZ  . TYR B 2 127 ? 194.142 208.365 186.350 1.00 12.93  ? 638 TYR B CZ  1 
ATOM   4067 O OH  . TYR B 2 127 ? 194.548 209.662 186.424 1.00 15.53  ? 638 TYR B OH  1 
ATOM   4068 N N   . THR B 2 128 ? 191.856 201.704 183.920 1.00 10.51  ? 639 THR B N   1 
ATOM   4069 C CA  . THR B 2 128 ? 191.165 200.430 184.002 1.00 8.67   ? 639 THR B CA  1 
ATOM   4070 C C   . THR B 2 128 ? 192.098 199.265 183.852 1.00 8.74   ? 639 THR B C   1 
ATOM   4071 O O   . THR B 2 128 ? 191.861 198.218 184.437 1.00 13.63  ? 639 THR B O   1 
ATOM   4072 C CB  . THR B 2 128 ? 190.051 200.322 182.972 1.00 9.50   ? 639 THR B CB  1 
ATOM   4073 O OG1 . THR B 2 128 ? 190.599 200.456 181.667 1.00 13.51  ? 639 THR B OG1 1 
ATOM   4074 C CG2 . THR B 2 128 ? 189.052 201.416 183.221 1.00 11.81  ? 639 THR B CG2 1 
ATOM   4075 N N   . GLN B 2 129 ? 193.207 199.434 183.153 1.00 10.70  ? 640 GLN B N   1 
ATOM   4076 C CA  . GLN B 2 129 ? 194.119 198.319 183.009 1.00 9.09   ? 640 GLN B CA  1 
ATOM   4077 C C   . GLN B 2 129 ? 194.908 198.108 184.281 1.00 8.81   ? 640 GLN B C   1 
ATOM   4078 O O   . GLN B 2 129 ? 195.290 196.981 184.600 1.00 9.50   ? 640 GLN B O   1 
ATOM   4079 C CB  . GLN B 2 129 ? 195.031 198.520 181.816 1.00 11.25  ? 640 GLN B CB  1 
ATOM   4080 C CG  . GLN B 2 129 ? 194.279 198.506 180.512 1.00 12.66  ? 640 GLN B CG  1 
ATOM   4081 C CD  . GLN B 2 129 ? 193.564 197.200 180.297 1.00 12.15  ? 640 GLN B CD  1 
ATOM   4082 O OE1 . GLN B 2 129 ? 194.156 196.131 180.426 1.00 13.84  ? 640 GLN B OE1 1 
ATOM   4083 N NE2 . GLN B 2 129 ? 192.285 197.271 179.982 1.00 11.89  ? 640 GLN B NE2 1 
ATOM   4084 N N   . ILE B 2 130 ? 195.345 199.179 184.926 1.00 9.69   ? 641 ILE B N   1 
ATOM   4085 C CA  . ILE B 2 130 ? 195.970 199.121 186.278 1.00 8.29   ? 641 ILE B CA  1 
ATOM   4086 C C   . ILE B 2 130 ? 195.032 198.439 187.268 1.00 7.92   ? 641 ILE B C   1 
ATOM   4087 O O   . ILE B 2 130 ? 195.488 197.523 187.918 1.00 9.96   ? 641 ILE B O   1 
ATOM   4088 C CB  . ILE B 2 130 ? 196.436 200.510 186.768 1.00 8.97   ? 641 ILE B CB  1 
ATOM   4089 C CG1 . ILE B 2 130 ? 197.414 201.176 185.803 1.00 9.73   ? 641 ILE B CG1 1 
ATOM   4090 C CG2 . ILE B 2 130 ? 196.985 200.462 188.183 1.00 10.30  ? 641 ILE B CG2 1 
ATOM   4091 C CD1 . ILE B 2 130 ? 197.707 202.609 186.157 1.00 14.47  ? 641 ILE B CD1 1 
ATOM   4092 N N   . ILE B 2 131 ? 193.777 198.859 187.345 1.00 8.72   ? 642 ILE B N   1 
ATOM   4093 C CA  . ILE B 2 131 ? 192.770 198.265 188.261 1.00 6.97   ? 642 ILE B CA  1 
ATOM   4094 C C   . ILE B 2 131 ? 192.571 196.787 187.910 1.00 6.83   ? 642 ILE B C   1 
ATOM   4095 O O   . ILE B 2 131 ? 192.594 196.019 188.844 1.00 7.39   ? 642 ILE B O   1 
ATOM   4096 C CB  . ILE B 2 131 ? 191.476 199.112 188.353 1.00 7.58   ? 642 ILE B CB  1 
ATOM   4097 C CG1 . ILE B 2 131 ? 191.763 200.599 188.554 1.00 6.28   ? 642 ILE B CG1 1 
ATOM   4098 C CG2 . ILE B 2 131 ? 190.531 198.574 189.408 1.00 6.91   ? 642 ILE B CG2 1 
ATOM   4099 C CD1 . ILE B 2 131 ? 190.554 201.484 188.437 1.00 5.31   ? 642 ILE B CD1 1 
ATOM   4100 N N   . TYR B 2 132 ? 192.410 196.404 186.639 1.00 7.38   ? 643 TYR B N   1 
ATOM   4101 C CA  . TYR B 2 132 ? 192.196 195.024 186.274 1.00 6.12   ? 643 TYR B CA  1 
ATOM   4102 C C   . TYR B 2 132 ? 193.383 194.170 186.669 1.00 6.01   ? 643 TYR B C   1 
ATOM   4103 O O   . TYR B 2 132 ? 193.196 193.058 187.168 1.00 7.63   ? 643 TYR B O   1 
ATOM   4104 C CB  . TYR B 2 132 ? 191.910 194.909 184.783 1.00 6.80   ? 643 TYR B CB  1 
ATOM   4105 C CG  . TYR B 2 132 ? 190.556 195.499 184.340 1.00 7.44   ? 643 TYR B CG  1 
ATOM   4106 C CD1 . TYR B 2 132 ? 189.676 196.113 185.247 1.00 8.22   ? 643 TYR B CD1 1 
ATOM   4107 C CD2 . TYR B 2 132 ? 190.177 195.390 183.028 1.00 7.43   ? 643 TYR B CD2 1 
ATOM   4108 C CE1 . TYR B 2 132 ? 188.490 196.597 184.827 1.00 7.38   ? 643 TYR B CE1 1 
ATOM   4109 C CE2 . TYR B 2 132 ? 188.961 195.879 182.623 1.00 7.07   ? 643 TYR B CE2 1 
ATOM   4110 C CZ  . TYR B 2 132 ? 188.127 196.482 183.524 1.00 7.72   ? 643 TYR B CZ  1 
ATOM   4111 O OH  . TYR B 2 132 ? 186.902 196.967 183.143 1.00 10.48  ? 643 TYR B OH  1 
ATOM   4112 N N   . GLY B 2 133 ? 194.602 194.673 186.493 1.00 7.46   ? 644 GLY B N   1 
ATOM   4113 C CA  . GLY B 2 133 ? 195.771 193.918 186.894 1.00 5.90   ? 644 GLY B CA  1 
ATOM   4114 C C   . GLY B 2 133 ? 195.782 193.665 188.392 1.00 5.67   ? 644 GLY B C   1 
ATOM   4115 O O   . GLY B 2 133 ? 196.078 192.554 188.828 1.00 6.39   ? 644 GLY B O   1 
ATOM   4116 N N   . LEU B 2 134 ? 195.492 194.672 189.179 1.00 6.69   ? 645 LEU B N   1 
ATOM   4117 C CA  . LEU B 2 134 ? 195.416 194.570 190.651 1.00 5.20   ? 645 LEU B CA  1 
ATOM   4118 C C   . LEU B 2 134 ? 194.292 193.625 191.098 1.00 4.77   ? 645 LEU B C   1 
ATOM   4119 O O   . LEU B 2 134 ? 194.509 193.007 192.111 1.00 5.06   ? 645 LEU B O   1 
ATOM   4120 C CB  . LEU B 2 134 ? 195.299 195.988 191.224 1.00 6.05   ? 645 LEU B CB  1 
ATOM   4121 C CG  . LEU B 2 134 ? 196.531 196.631 191.845 1.00 4.92   ? 645 LEU B CG  1 
ATOM   4122 C CD1 . LEU B 2 134 ? 197.814 196.122 191.231 1.00 7.32   ? 645 LEU B CD1 1 
ATOM   4123 C CD2 . LEU B 2 134 ? 196.438 198.133 191.713 1.00 3.98   ? 645 LEU B CD2 1 
ATOM   4124 N N   . LEU B 2 135 ? 193.161 193.485 190.383 1.00 5.44   ? 646 LEU B N   1 
ATOM   4125 C CA  . LEU B 2 135 ? 192.103 192.554 190.735 1.00 4.33   ? 646 LEU B CA  1 
ATOM   4126 C C   . LEU B 2 135 ? 192.553 191.122 190.522 1.00 3.66   ? 646 LEU B C   1 
ATOM   4127 O O   . LEU B 2 135 ? 192.282 190.256 191.364 1.00 4.23   ? 646 LEU B O   1 
ATOM   4128 C CB  . LEU B 2 135 ? 190.859 192.847 189.893 1.00 4.83   ? 646 LEU B CB  1 
ATOM   4129 C CG  . LEU B 2 135 ? 190.103 194.146 190.183 1.00 3.64   ? 646 LEU B CG  1 
ATOM   4130 C CD1 . LEU B 2 135 ? 189.080 194.380 189.119 1.00 5.23   ? 646 LEU B CD1 1 
ATOM   4131 C CD2 . LEU B 2 135 ? 189.420 194.036 191.454 1.00 4.89   ? 646 LEU B CD2 1 
ATOM   4132 N N   . GLU B 2 136 ? 193.284 190.879 189.438 1.00 6.27   ? 647 GLU B N   1 
ATOM   4133 C CA  . GLU B 2 136 ? 193.842 189.564 189.161 1.00 5.77   ? 647 GLU B CA  1 
ATOM   4134 C C   . GLU B 2 136 ? 194.879 189.156 190.196 1.00 5.33   ? 647 GLU B C   1 
ATOM   4135 O O   . GLU B 2 136 ? 194.857 188.025 190.686 1.00 6.57   ? 647 GLU B O   1 
ATOM   4136 C CB  . GLU B 2 136 ? 194.481 189.547 187.791 1.00 7.08   ? 647 GLU B CB  1 
ATOM   4137 C CG  . GLU B 2 136 ? 195.113 188.249 187.415 1.00 11.05  ? 647 GLU B CG  1 
ATOM   4138 C CD  . GLU B 2 136 ? 195.712 188.313 186.083 1.00 12.40  ? 647 GLU B CD  1 
ATOM   4139 O OE1 . GLU B 2 136 ? 195.272 189.110 185.296 1.00 13.38  ? 647 GLU B OE1 1 
ATOM   4140 O OE2 . GLU B 2 136 ? 196.646 187.583 185.849 1.00 14.53  ? 647 GLU B OE2 1 
ATOM   4141 N N   . GLU B 2 137 ? 195.778 190.075 190.561 1.00 5.33   ? 648 GLU B N   1 
ATOM   4142 C CA  . GLU B 2 137 ? 196.811 189.753 191.528 1.00 4.20   ? 648 GLU B CA  1 
ATOM   4143 C C   . GLU B 2 137 ? 196.218 189.410 192.863 1.00 3.76   ? 648 GLU B C   1 
ATOM   4144 O O   . GLU B 2 137 ? 196.716 188.527 193.556 1.00 6.59   ? 648 GLU B O   1 
ATOM   4145 C CB  . GLU B 2 137 ? 197.765 190.918 191.743 1.00 10.68  ? 648 GLU B CB  1 
ATOM   4146 C CG  . GLU B 2 137 ? 198.682 191.235 190.606 1.00 6.82   ? 648 GLU B CG  1 
ATOM   4147 C CD  . GLU B 2 137 ? 199.506 192.472 190.883 1.00 0.01   ? 648 GLU B CD  1 
ATOM   4148 O OE1 . GLU B 2 137 ? 199.297 193.072 191.912 1.00 0.01   ? 648 GLU B OE1 1 
ATOM   4149 O OE2 . GLU B 2 137 ? 200.329 192.818 190.070 1.00 0.00   ? 648 GLU B OE2 1 
ATOM   4150 N N   . SER B 2 138 ? 195.169 190.112 193.258 1.00 4.58   ? 649 SER B N   1 
ATOM   4151 C CA  . SER B 2 138 ? 194.543 189.831 194.524 1.00 2.78   ? 649 SER B CA  1 
ATOM   4152 C C   . SER B 2 138 ? 193.906 188.453 194.536 1.00 2.96   ? 649 SER B C   1 
ATOM   4153 O O   . SER B 2 138 ? 194.130 187.683 195.472 1.00 4.05   ? 649 SER B O   1 
ATOM   4154 C CB  . SER B 2 138 ? 193.527 190.880 194.850 1.00 2.70   ? 649 SER B CB  1 
ATOM   4155 O OG  . SER B 2 138 ? 192.935 190.607 196.075 1.00 7.43   ? 649 SER B OG  1 
ATOM   4156 N N   . GLN B 2 139 ? 193.183 188.080 193.475 1.00 3.88   ? 650 GLN B N   1 
ATOM   4157 C CA  . GLN B 2 139 ? 192.527 186.777 193.462 1.00 3.02   ? 650 GLN B CA  1 
ATOM   4158 C C   . GLN B 2 139 ? 193.524 185.649 193.501 1.00 3.87   ? 650 GLN B C   1 
ATOM   4159 O O   . GLN B 2 139 ? 193.257 184.609 194.105 1.00 4.18   ? 650 GLN B O   1 
ATOM   4160 C CB  . GLN B 2 139 ? 191.650 186.600 192.242 1.00 5.31   ? 650 GLN B CB  1 
ATOM   4161 C CG  . GLN B 2 139 ? 190.839 185.279 192.209 1.00 5.99   ? 650 GLN B CG  1 
ATOM   4162 C CD  . GLN B 2 139 ? 189.859 185.167 193.273 1.00 6.14   ? 650 GLN B CD  1 
ATOM   4163 O OE1 . GLN B 2 139 ? 189.480 186.179 193.852 1.00 7.17   ? 650 GLN B OE1 1 
ATOM   4164 N NE2 . GLN B 2 139 ? 189.394 183.965 193.535 1.00 7.94   ? 650 GLN B NE2 1 
ATOM   4165 N N   . ASN B 2 140 ? 194.681 185.843 192.888 1.00 4.16   ? 651 ASN B N   1 
ATOM   4166 C CA  . ASN B 2 140 ? 195.704 184.820 192.897 1.00 3.34   ? 651 ASN B CA  1 
ATOM   4167 C C   . ASN B 2 140 ? 196.263 184.577 194.292 1.00 2.84   ? 651 ASN B C   1 
ATOM   4168 O O   . ASN B 2 140 ? 196.748 183.486 194.586 1.00 3.53   ? 651 ASN B O   1 
ATOM   4169 C CB  . ASN B 2 140 ? 196.838 185.179 191.972 1.00 4.71   ? 651 ASN B CB  1 
ATOM   4170 C CG  . ASN B 2 140 ? 196.527 185.029 190.533 1.00 7.38   ? 651 ASN B CG  1 
ATOM   4171 O OD1 . ASN B 2 140 ? 195.600 184.328 190.129 1.00 9.61   ? 651 ASN B OD1 1 
ATOM   4172 N ND2 . ASN B 2 140 ? 197.323 185.667 189.726 1.00 9.67   ? 651 ASN B ND2 1 
ATOM   4173 N N   . GLN B 2 141 ? 196.217 185.577 195.170 1.00 3.65   ? 652 GLN B N   1 
ATOM   4174 C CA  . GLN B 2 141 ? 196.736 185.398 196.503 1.00 2.94   ? 652 GLN B CA  1 
ATOM   4175 C C   . GLN B 2 141 ? 195.660 184.777 197.354 1.00 0.57   ? 652 GLN B C   1 
ATOM   4176 O O   . GLN B 2 141 ? 195.946 183.974 198.242 1.00 2.92   ? 652 GLN B O   1 
ATOM   4177 C CB  . GLN B 2 141 ? 197.178 186.737 197.059 1.00 3.96   ? 652 GLN B CB  1 
ATOM   4178 C CG  . GLN B 2 141 ? 198.348 187.297 196.324 1.00 6.06   ? 652 GLN B CG  1 
ATOM   4179 C CD  . GLN B 2 141 ? 198.684 188.681 196.727 1.00 9.75   ? 652 GLN B CD  1 
ATOM   4180 O OE1 . GLN B 2 141 ? 199.194 188.948 197.817 1.00 16.73  ? 652 GLN B OE1 1 
ATOM   4181 N NE2 . GLN B 2 141 ? 198.380 189.599 195.829 1.00 1.22   ? 652 GLN B NE2 1 
ATOM   4182 N N   . GLN B 2 142 ? 194.415 185.126 197.065 1.00 2.40   ? 653 GLN B N   1 
ATOM   4183 C CA  . GLN B 2 142 ? 193.309 184.589 197.812 1.00 1.58   ? 653 GLN B CA  1 
ATOM   4184 C C   . GLN B 2 142 ? 193.145 183.105 197.578 1.00 0.20   ? 653 GLN B C   1 
ATOM   4185 O O   . GLN B 2 142 ? 192.961 182.372 198.541 1.00 0.01   ? 653 GLN B O   1 
ATOM   4186 C CB  . GLN B 2 142 ? 192.016 185.282 197.443 1.00 4.81   ? 653 GLN B CB  1 
ATOM   4187 C CG  . GLN B 2 142 ? 190.826 184.814 198.238 1.00 6.33   ? 653 GLN B CG  1 
ATOM   4188 C CD  . GLN B 2 142 ? 189.585 185.457 197.790 1.00 8.95   ? 653 GLN B CD  1 
ATOM   4189 O OE1 . GLN B 2 142 ? 189.600 186.624 197.383 1.00 10.72  ? 653 GLN B OE1 1 
ATOM   4190 N NE2 . GLN B 2 142 ? 188.493 184.716 197.847 1.00 14.60  ? 653 GLN B NE2 1 
ATOM   4191 N N   . GLU B 2 143 ? 193.245 182.633 196.323 1.00 3.63   ? 654 GLU B N   1 
ATOM   4192 C CA  . GLU B 2 143 ? 193.048 181.202 196.096 1.00 0.37   ? 654 GLU B CA  1 
ATOM   4193 C C   . GLU B 2 143 ? 194.134 180.384 196.743 1.00 0.62   ? 654 GLU B C   1 
ATOM   4194 O O   . GLU B 2 143 ? 193.874 179.274 197.205 1.00 1.16   ? 654 GLU B O   1 
ATOM   4195 C CB  . GLU B 2 143 ? 192.931 180.831 194.608 1.00 3.40   ? 654 GLU B CB  1 
ATOM   4196 C CG  . GLU B 2 143 ? 191.635 181.322 193.994 1.00 0.00   ? 654 GLU B CG  1 
ATOM   4197 C CD  . GLU B 2 143 ? 191.265 180.863 192.549 1.00 7.85   ? 654 GLU B CD  1 
ATOM   4198 O OE1 . GLU B 2 143 ? 191.748 179.874 192.020 1.00 2.57   ? 654 GLU B OE1 1 
ATOM   4199 O OE2 . GLU B 2 143 ? 190.457 181.559 191.990 1.00 0.00   ? 654 GLU B OE2 1 
ATOM   4200 N N   . LYS B 2 144 ? 195.353 180.876 196.873 1.00 1.22   ? 655 LYS B N   1 
ATOM   4201 C CA  . LYS B 2 144 ? 196.477 180.094 197.463 1.00 0.01   ? 655 LYS B CA  1 
ATOM   4202 C C   . LYS B 2 144 ? 196.397 180.073 198.973 1.00 0.03   ? 655 LYS B C   1 
ATOM   4203 O O   . LYS B 2 144 ? 196.738 179.066 199.514 1.00 0.42   ? 655 LYS B O   1 
ATOM   4204 C CB  . LYS B 2 144 ? 197.819 180.486 196.855 1.00 0.00   ? 655 LYS B CB  1 
ATOM   4205 C CG  . LYS B 2 144 ? 199.052 179.842 197.450 1.00 1.72   ? 655 LYS B CG  1 
ATOM   4206 C CD  . LYS B 2 144 ? 199.623 178.764 196.593 1.00 0.01   ? 655 LYS B CD  1 
ATOM   4207 C CE  . LYS B 2 144 ? 201.107 178.576 196.796 1.00 0.00   ? 655 LYS B CE  1 
ATOM   4208 N NZ  . LYS B 2 144 ? 201.454 177.143 196.904 1.00 0.00   ? 655 LYS B NZ  1 
ATOM   4209 N N   . ASN B 2 145 ? 195.800 181.078 199.591 1.00 0.03   ? 656 ASN B N   1 
ATOM   4210 C CA  . ASN B 2 145 ? 195.721 181.241 201.052 1.00 0.04   ? 656 ASN B CA  1 
ATOM   4211 C C   . ASN B 2 145 ? 194.602 180.349 201.542 1.00 0.08   ? 656 ASN B C   1 
ATOM   4212 O O   . ASN B 2 145 ? 194.697 179.866 202.612 1.00 1.96   ? 656 ASN B O   1 
ATOM   4213 C CB  . ASN B 2 145 ? 195.575 182.724 201.411 1.00 1.00   ? 656 ASN B CB  1 
ATOM   4214 C CG  . ASN B 2 145 ? 196.838 183.476 201.733 1.00 0.99   ? 656 ASN B CG  1 
ATOM   4215 O OD1 . ASN B 2 145 ? 197.908 182.907 201.864 1.00 3.24   ? 656 ASN B OD1 1 
ATOM   4216 N ND2 . ASN B 2 145 ? 196.708 184.776 201.863 1.00 4.74   ? 656 ASN B ND2 1 
ATOM   4217 N N   . GLU B 2 146 ? 193.629 180.083 200.718 1.00 2.84   ? 657 GLU B N   1 
ATOM   4218 C CA  . GLU B 2 146 ? 192.448 179.247 200.997 1.00 0.32   ? 657 GLU B CA  1 
ATOM   4219 C C   . GLU B 2 146 ? 192.684 177.769 200.817 1.00 0.18   ? 657 GLU B C   1 
ATOM   4220 O O   . GLU B 2 146 ? 191.984 177.039 201.439 1.00 1.39   ? 657 GLU B O   1 
ATOM   4221 C CB  . GLU B 2 146 ? 191.410 179.657 199.975 1.00 1.21   ? 657 GLU B CB  1 
ATOM   4222 C CG  . GLU B 2 146 ? 190.821 181.022 200.271 1.00 2.91   ? 657 GLU B CG  1 
ATOM   4223 C CD  . GLU B 2 146 ? 189.597 181.444 199.480 1.00 0.00   ? 657 GLU B CD  1 
ATOM   4224 O OE1 . GLU B 2 146 ? 189.532 181.148 198.270 1.00 0.19   ? 657 GLU B OE1 1 
ATOM   4225 O OE2 . GLU B 2 146 ? 188.716 182.088 200.074 1.00 8.16   ? 657 GLU B OE2 1 
ATOM   4226 N N   . GLN B 2 147 ? 193.611 177.366 199.969 1.00 1.72   ? 658 GLN B N   1 
ATOM   4227 C CA  . GLN B 2 147 ? 193.992 175.981 199.739 1.00 0.10   ? 658 GLN B CA  1 
ATOM   4228 C C   . GLN B 2 147 ? 194.872 175.515 200.866 1.00 0.09   ? 658 GLN B C   1 
ATOM   4229 O O   . GLN B 2 147 ? 194.832 174.375 201.138 1.00 1.59   ? 658 GLN B O   1 
ATOM   4230 C CB  . GLN B 2 147 ? 194.857 176.016 198.512 1.00 0.39   ? 658 GLN B CB  1 
ATOM   4231 C CG  . GLN B 2 147 ? 195.018 174.669 197.849 1.00 1.69   ? 658 GLN B CG  1 
ATOM   4232 C CD  . GLN B 2 147 ? 196.243 174.567 196.988 1.00 2.24   ? 658 GLN B CD  1 
ATOM   4233 O OE1 . GLN B 2 147 ? 196.917 175.548 196.725 1.00 5.02   ? 658 GLN B OE1 1 
ATOM   4234 N NE2 . GLN B 2 147 ? 196.532 173.365 196.536 1.00 2.37   ? 658 GLN B NE2 1 
ATOM   4235 N N   . ASP B 2 148 ? 195.634 176.380 201.488 1.00 1.34   ? 659 ASP B N   1 
ATOM   4236 C CA  . ASP B 2 148 ? 196.573 176.108 202.570 1.00 0.63   ? 659 ASP B CA  1 
ATOM   4237 C C   . ASP B 2 148 ? 195.841 176.151 203.896 1.00 0.89   ? 659 ASP B C   1 
ATOM   4238 O O   . ASP B 2 148 ? 196.403 175.722 204.877 1.00 1.77   ? 659 ASP B O   1 
ATOM   4239 C CB  . ASP B 2 148 ? 197.633 177.192 202.532 1.00 30.00  ? 659 ASP B CB  1 
ATOM   4240 C CG  . ASP B 2 148 ? 198.754 177.035 201.531 1.00 30.00  ? 659 ASP B CG  1 
ATOM   4241 O OD1 . ASP B 2 148 ? 198.673 176.160 200.663 1.00 30.00  ? 659 ASP B OD1 1 
ATOM   4242 O OD2 . ASP B 2 148 ? 199.704 177.810 201.633 1.00 30.00  ? 659 ASP B OD2 1 
ATOM   4243 N N   . LEU B 2 149 ? 194.637 176.648 203.931 1.00 1.66   ? 660 LEU B N   1 
ATOM   4244 C CA  . LEU B 2 149 ? 193.829 176.642 205.147 1.00 0.84   ? 660 LEU B CA  1 
ATOM   4245 C C   . LEU B 2 149 ? 192.921 175.434 205.107 1.00 1.01   ? 660 LEU B C   1 
ATOM   4246 O O   . LEU B 2 149 ? 192.397 175.090 206.141 1.00 1.92   ? 660 LEU B O   1 
ATOM   4247 C CB  . LEU B 2 149 ? 193.028 177.937 205.157 1.00 1.80   ? 660 LEU B CB  1 
ATOM   4248 C CG  . LEU B 2 149 ? 193.621 179.178 205.810 1.00 0.70   ? 660 LEU B CG  1 
ATOM   4249 C CD1 . LEU B 2 149 ? 192.667 180.338 205.633 1.00 0.74   ? 660 LEU B CD1 1 
ATOM   4250 C CD2 . LEU B 2 149 ? 193.891 178.952 207.277 1.00 1.28   ? 660 LEU B CD2 1 
ATOM   4251 N N   . LEU B 2 150 ? 192.765 174.819 203.957 1.00 1.41   ? 661 LEU B N   1 
ATOM   4252 C CA  . LEU B 2 150 ? 192.014 173.577 203.788 1.00 0.63   ? 661 LEU B CA  1 
ATOM   4253 C C   . LEU B 2 150 ? 192.989 172.440 203.911 1.00 1.15   ? 661 LEU B C   1 
ATOM   4254 O O   . LEU B 2 150 ? 192.555 171.345 203.863 1.00 2.43   ? 661 LEU B O   1 
ATOM   4255 C CB  . LEU B 2 150 ? 191.299 173.649 202.445 1.00 1.00   ? 661 LEU B CB  1 
ATOM   4256 C CG  . LEU B 2 150 ? 190.039 174.498 202.347 1.00 0.51   ? 661 LEU B CG  1 
ATOM   4257 C CD1 . LEU B 2 150 ? 189.547 174.514 200.919 1.00 1.64   ? 661 LEU B CD1 1 
ATOM   4258 C CD2 . LEU B 2 150 ? 188.957 173.975 203.261 1.00 1.47   ? 661 LEU B CD2 1 
ATOM   4259 N N   . ALA B 2 151 ? 194.254 172.727 204.128 1.00 1.34   ? 662 ALA B N   1 
ATOM   4260 C CA  . ALA B 2 151 ? 195.328 171.757 204.414 1.00 1.02   ? 662 ALA B CA  1 
ATOM   4261 C C   . ALA B 2 151 ? 195.742 171.829 205.877 1.00 2.59   ? 662 ALA B C   1 
ATOM   4262 O O   . ALA B 2 151 ? 194.929 172.050 206.773 1.00 2.79   ? 662 ALA B O   1 
ATOM   4263 C CB  . ALA B 2 151 ? 196.498 171.997 203.543 1.00 30.00  ? 662 ALA B CB  1 
ATOM   4264 N N   . GLU C 3 1   ? 162.773 221.287 208.788 1.00 44.51  ? 1   GLU H N   1 
ATOM   4265 C CA  . GLU C 3 1   ? 162.961 220.690 210.097 1.00 43.73  ? 1   GLU H CA  1 
ATOM   4266 C C   . GLU C 3 1   ? 162.515 219.216 210.065 1.00 35.92  ? 1   GLU H C   1 
ATOM   4267 O O   . GLU C 3 1   ? 161.418 218.908 209.578 1.00 35.43  ? 1   GLU H O   1 
ATOM   4268 C CB  . GLU C 3 1   ? 162.186 221.486 211.200 1.00 49.30  ? 1   GLU H CB  1 
ATOM   4269 C CG  . GLU C 3 1   ? 162.374 220.966 212.722 1.00 52.43  ? 1   GLU H CG  1 
ATOM   4270 C CD  . GLU C 3 1   ? 161.652 221.812 213.783 1.00 56.11  ? 1   GLU H CD  1 
ATOM   4271 O OE1 . GLU C 3 1   ? 160.492 221.564 214.066 1.00 61.82  ? 1   GLU H OE1 1 
ATOM   4272 O OE2 . GLU C 3 1   ? 162.280 222.701 214.313 1.00 67.48  ? 1   GLU H OE2 1 
ATOM   4273 N N   . VAL C 3 2   ? 163.384 218.320 210.584 1.00 34.09  ? 2   VAL H N   1 
ATOM   4274 C CA  . VAL C 3 2   ? 163.137 216.885 210.715 1.00 31.10  ? 2   VAL H CA  1 
ATOM   4275 C C   . VAL C 3 2   ? 162.423 216.566 211.994 1.00 32.46  ? 2   VAL H C   1 
ATOM   4276 O O   . VAL C 3 2   ? 162.846 216.973 213.075 1.00 33.82  ? 2   VAL H O   1 
ATOM   4277 C CB  . VAL C 3 2   ? 164.446 216.102 210.647 1.00 25.52  ? 2   VAL H CB  1 
ATOM   4278 C CG1 . VAL C 3 2   ? 164.196 214.638 210.936 1.00 23.48  ? 2   VAL H CG1 1 
ATOM   4279 C CG2 . VAL C 3 2   ? 164.985 216.260 209.268 1.00 25.26  ? 2   VAL H CG2 1 
ATOM   4280 N N   . GLN C 3 3   ? 161.339 215.830 211.868 1.00 29.87  ? 3   GLN H N   1 
ATOM   4281 C CA  . GLN C 3 3   ? 160.576 215.447 213.022 1.00 29.03  ? 3   GLN H CA  1 
ATOM   4282 C C   . GLN C 3 3   ? 160.278 213.972 213.010 1.00 26.14  ? 3   GLN H C   1 
ATOM   4283 O O   . GLN C 3 3   ? 159.894 213.393 211.986 1.00 26.55  ? 3   GLN H O   1 
ATOM   4284 C CB  . GLN C 3 3   ? 159.271 216.228 213.070 1.00 33.30  ? 3   GLN H CB  1 
ATOM   4285 C CG  . GLN C 3 3   ? 159.452 217.726 213.191 1.00 40.77  ? 3   GLN H CG  1 
ATOM   4286 C CD  . GLN C 3 3   ? 158.145 218.436 213.294 1.00 45.02  ? 3   GLN H CD  1 
ATOM   4287 O OE1 . GLN C 3 3   ? 157.090 217.812 213.116 1.00 43.53  ? 3   GLN H OE1 1 
ATOM   4288 N NE2 . GLN C 3 3   ? 158.174 219.732 213.578 1.00 55.20  ? 3   GLN H NE2 1 
ATOM   4289 N N   . LEU C 3 4   ? 160.446 213.369 214.168 1.00 23.92  ? 4   LEU H N   1 
ATOM   4290 C CA  . LEU C 3 4   ? 160.143 211.978 214.367 1.00 21.04  ? 4   LEU H CA  1 
ATOM   4291 C C   . LEU C 3 4   ? 159.163 211.942 215.506 1.00 22.73  ? 4   LEU H C   1 
ATOM   4292 O O   . LEU C 3 4   ? 159.451 212.481 216.577 1.00 23.69  ? 4   LEU H O   1 
ATOM   4293 C CB  . LEU C 3 4   ? 161.413 211.212 214.732 1.00 19.52  ? 4   LEU H CB  1 
ATOM   4294 C CG  . LEU C 3 4   ? 162.590 211.277 213.761 1.00 17.17  ? 4   LEU H CG  1 
ATOM   4295 C CD1 . LEU C 3 4   ? 163.747 210.556 214.384 1.00 15.65  ? 4   LEU H CD1 1 
ATOM   4296 C CD2 . LEU C 3 4   ? 162.239 210.669 212.455 1.00 19.07  ? 4   LEU H CD2 1 
ATOM   4297 N N   . VAL C 3 5   ? 157.976 211.410 215.281 1.00 23.59  ? 5   VAL H N   1 
ATOM   4298 C CA  . VAL C 3 5   ? 156.998 211.422 216.350 1.00 23.50  ? 5   VAL H CA  1 
ATOM   4299 C C   . VAL C 3 5   ? 156.519 210.055 216.736 1.00 23.30  ? 5   VAL H C   1 
ATOM   4300 O O   . VAL C 3 5   ? 155.852 209.378 215.951 1.00 24.66  ? 5   VAL H O   1 
ATOM   4301 C CB  . VAL C 3 5   ? 155.788 212.265 215.922 1.00 25.25  ? 5   VAL H CB  1 
ATOM   4302 C CG1 . VAL C 3 5   ? 154.739 212.285 217.027 1.00 27.06  ? 5   VAL H CG1 1 
ATOM   4303 C CG2 . VAL C 3 5   ? 156.254 213.675 215.580 1.00 26.19  ? 5   VAL H CG2 1 
ATOM   4304 N N   . GLU C 3 6   ? 156.808 209.665 217.965 1.00 24.86  ? 6   GLU H N   1 
ATOM   4305 C CA  . GLU C 3 6   ? 156.355 208.384 218.439 1.00 24.29  ? 6   GLU H CA  1 
ATOM   4306 C C   . GLU C 3 6   ? 154.887 208.484 218.798 1.00 28.35  ? 6   GLU H C   1 
ATOM   4307 O O   . GLU C 3 6   ? 154.461 209.422 219.476 1.00 28.11  ? 6   GLU H O   1 
ATOM   4308 C CB  . GLU C 3 6   ? 157.188 207.924 219.619 1.00 24.02  ? 6   GLU H CB  1 
ATOM   4309 C CG  . GLU C 3 6   ? 158.649 207.766 219.282 1.00 21.28  ? 6   GLU H CG  1 
ATOM   4310 C CD  . GLU C 3 6   ? 159.447 209.026 219.437 1.00 22.13  ? 6   GLU H CD  1 
ATOM   4311 O OE1 . GLU C 3 6   ? 158.888 210.101 219.650 1.00 25.89  ? 6   GLU H OE1 1 
ATOM   4312 O OE2 . GLU C 3 6   ? 160.643 208.936 219.395 1.00 20.83  ? 6   GLU H OE2 1 
ATOM   4313 N N   . THR C 3 7   ? 154.127 207.499 218.370 1.00 28.19  ? 7   THR H N   1 
ATOM   4314 C CA  . THR C 3 7   ? 152.700 207.395 218.621 1.00 28.47  ? 7   THR H CA  1 
ATOM   4315 C C   . THR C 3 7   ? 152.398 205.988 219.095 1.00 27.78  ? 7   THR H C   1 
ATOM   4316 O O   . THR C 3 7   ? 151.498 205.330 218.574 1.00 28.07  ? 7   THR H O   1 
ATOM   4317 C CB  . THR C 3 7   ? 151.868 207.682 217.365 1.00 30.39  ? 7   THR H CB  1 
ATOM   4318 O OG1 . THR C 3 7   ? 152.231 206.766 216.340 1.00 27.90  ? 7   THR H OG1 1 
ATOM   4319 C CG2 . THR C 3 7   ? 152.147 209.093 216.867 1.00 31.00  ? 7   THR H CG2 1 
ATOM   4320 N N   . GLY C 3 8   ? 153.209 205.500 220.021 1.00 26.92  ? 8   GLY H N   1 
ATOM   4321 C CA  . GLY C 3 8   ? 153.108 204.133 220.507 1.00 26.53  ? 8   GLY H CA  1 
ATOM   4322 C C   . GLY C 3 8   ? 152.227 203.988 221.734 1.00 28.31  ? 8   GLY H C   1 
ATOM   4323 O O   . GLY C 3 8   ? 151.367 204.825 222.002 1.00 31.14  ? 8   GLY H O   1 
ATOM   4324 N N   . GLY C 3 9   ? 152.415 202.894 222.461 1.00 28.52  ? 9   GLY H N   1 
ATOM   4325 C CA  . GLY C 3 9   ? 151.576 202.592 223.601 1.00 31.22  ? 9   GLY H CA  1 
ATOM   4326 C C   . GLY C 3 9   ? 152.119 203.085 224.931 1.00 31.57  ? 9   GLY H C   1 
ATOM   4327 O O   . GLY C 3 9   ? 153.077 203.856 224.984 1.00 28.23  ? 9   GLY H O   1 
ATOM   4328 N N   . GLY C 3 10  ? 151.464 202.617 225.999 1.00 32.73  ? 10  GLY H N   1 
ATOM   4329 C CA  . GLY C 3 10  ? 151.745 202.958 227.388 1.00 32.64  ? 10  GLY H CA  1 
ATOM   4330 C C   . GLY C 3 10  ? 151.884 201.717 228.266 1.00 33.26  ? 10  GLY H C   1 
ATOM   4331 O O   . GLY C 3 10  ? 152.854 200.965 228.162 1.00 32.61  ? 10  GLY H O   1 
ATOM   4332 N N   . LEU C 3 11  ? 150.927 201.550 229.187 1.00 35.97  ? 11  LEU H N   1 
ATOM   4333 C CA  . LEU C 3 11  ? 150.929 200.452 230.151 1.00 36.98  ? 11  LEU H CA  1 
ATOM   4334 C C   . LEU C 3 11  ? 150.410 199.126 229.627 1.00 36.10  ? 11  LEU H C   1 
ATOM   4335 O O   . LEU C 3 11  ? 149.307 199.029 229.086 1.00 37.16  ? 11  LEU H O   1 
ATOM   4336 C CB  . LEU C 3 11  ? 150.097 200.857 231.371 1.00 39.54  ? 11  LEU H CB  1 
ATOM   4337 C CG  . LEU C 3 11  ? 149.914 199.800 232.490 1.00 39.56  ? 11  LEU H CG  1 
ATOM   4338 C CD1 . LEU C 3 11  ? 151.229 199.465 233.141 1.00 39.38  ? 11  LEU H CD1 1 
ATOM   4339 C CD2 . LEU C 3 11  ? 148.961 200.353 233.521 1.00 42.74  ? 11  LEU H CD2 1 
ATOM   4340 N N   . VAL C 3 12  ? 151.230 198.113 229.827 1.00 37.18  ? 12  VAL H N   1 
ATOM   4341 C CA  . VAL C 3 12  ? 151.004 196.730 229.456 1.00 38.63  ? 12  VAL H CA  1 
ATOM   4342 C C   . VAL C 3 12  ? 151.373 195.780 230.606 1.00 40.53  ? 12  VAL H C   1 
ATOM   4343 O O   . VAL C 3 12  ? 152.262 196.072 231.413 1.00 38.81  ? 12  VAL H O   1 
ATOM   4344 C CB  . VAL C 3 12  ? 151.747 196.490 228.142 1.00 36.46  ? 12  VAL H CB  1 
ATOM   4345 C CG1 . VAL C 3 12  ? 153.174 196.768 228.332 1.00 36.18  ? 12  VAL H CG1 1 
ATOM   4346 C CG2 . VAL C 3 12  ? 151.554 195.073 227.622 1.00 37.69  ? 12  VAL H CG2 1 
ATOM   4347 N N   . GLN C 3 13  ? 150.685 194.651 230.692 1.00 42.25  ? 13  GLN H N   1 
ATOM   4348 C CA  . GLN C 3 13  ? 150.985 193.670 231.719 1.00 42.51  ? 13  GLN H CA  1 
ATOM   4349 C C   . GLN C 3 13  ? 152.244 192.885 231.327 1.00 38.47  ? 13  GLN H C   1 
ATOM   4350 O O   . GLN C 3 13  ? 152.537 192.770 230.135 1.00 39.28  ? 13  GLN H O   1 
ATOM   4351 C CB  . GLN C 3 13  ? 149.816 192.683 231.866 1.00 43.20  ? 13  GLN H CB  1 
ATOM   4352 C CG  . GLN C 3 13  ? 149.710 191.608 230.747 1.00 44.21  ? 13  GLN H CG  1 
ATOM   4353 C CD  . GLN C 3 13  ? 148.985 192.059 229.522 1.00 41.01  ? 13  GLN H CD  1 
ATOM   4354 O OE1 . GLN C 3 13  ? 148.873 193.260 229.231 1.00 45.13  ? 13  GLN H OE1 1 
ATOM   4355 N NE2 . GLN C 3 13  ? 148.487 191.093 228.765 1.00 47.84  ? 13  GLN H NE2 1 
ATOM   4356 N N   . PRO C 3 14  ? 153.011 192.341 232.276 1.00 38.92  ? 14  PRO H N   1 
ATOM   4357 C CA  . PRO C 3 14  ? 154.137 191.481 232.030 1.00 38.83  ? 14  PRO H CA  1 
ATOM   4358 C C   . PRO C 3 14  ? 153.697 190.295 231.233 1.00 36.35  ? 14  PRO H C   1 
ATOM   4359 O O   . PRO C 3 14  ? 152.668 189.688 231.522 1.00 37.23  ? 14  PRO H O   1 
ATOM   4360 C CB  . PRO C 3 14  ? 154.559 191.062 233.433 1.00 38.21  ? 14  PRO H CB  1 
ATOM   4361 C CG  . PRO C 3 14  ? 154.095 192.179 234.294 1.00 41.68  ? 14  PRO H CG  1 
ATOM   4362 C CD  . PRO C 3 14  ? 152.807 192.651 233.662 1.00 40.62  ? 14  PRO H CD  1 
ATOM   4363 N N   . GLY C 3 15  ? 154.498 189.945 230.259 1.00 34.30  ? 15  GLY H N   1 
ATOM   4364 C CA  . GLY C 3 15  ? 154.225 188.800 229.413 1.00 32.46  ? 15  GLY H CA  1 
ATOM   4365 C C   . GLY C 3 15  ? 153.295 189.119 228.248 1.00 33.20  ? 15  GLY H C   1 
ATOM   4366 O O   . GLY C 3 15  ? 152.965 188.234 227.459 1.00 32.75  ? 15  GLY H O   1 
ATOM   4367 N N   . GLY C 3 16  ? 152.883 190.374 228.117 1.00 35.03  ? 16  GLY H N   1 
ATOM   4368 C CA  . GLY C 3 16  ? 151.975 190.775 227.057 1.00 36.57  ? 16  GLY H CA  1 
ATOM   4369 C C   . GLY C 3 16  ? 152.732 191.284 225.842 1.00 32.65  ? 16  GLY H C   1 
ATOM   4370 O O   . GLY C 3 16  ? 153.835 190.818 225.526 1.00 31.84  ? 16  GLY H O   1 
ATOM   4371 N N   . SER C 3 17  ? 152.107 192.178 225.094 1.00 33.16  ? 17  SER H N   1 
ATOM   4372 C CA  . SER C 3 17  ? 152.742 192.700 223.903 1.00 31.85  ? 17  SER H CA  1 
ATOM   4373 C C   . SER C 3 17  ? 152.318 194.137 223.706 1.00 31.25  ? 17  SER H C   1 
ATOM   4374 O O   . SER C 3 17  ? 151.254 194.558 224.166 1.00 31.93  ? 17  SER H O   1 
ATOM   4375 C CB  . SER C 3 17  ? 152.376 191.872 222.696 1.00 31.78  ? 17  SER H CB  1 
ATOM   4376 O OG  . SER C 3 17  ? 151.018 191.989 222.386 1.00 33.74  ? 17  SER H OG  1 
ATOM   4377 N N   . LEU C 3 18  ? 153.175 194.897 223.051 1.00 29.49  ? 18  LEU H N   1 
ATOM   4378 C CA  . LEU C 3 18  ? 152.891 196.294 222.769 1.00 28.55  ? 18  LEU H CA  1 
ATOM   4379 C C   . LEU C 3 18  ? 153.591 196.731 221.505 1.00 24.60  ? 18  LEU H C   1 
ATOM   4380 O O   . LEU C 3 18  ? 154.753 196.388 221.286 1.00 27.64  ? 18  LEU H O   1 
ATOM   4381 C CB  . LEU C 3 18  ? 153.276 197.153 223.984 1.00 29.47  ? 18  LEU H CB  1 
ATOM   4382 C CG  . LEU C 3 18  ? 152.940 198.655 223.947 1.00 27.68  ? 18  LEU H CG  1 
ATOM   4383 C CD1 . LEU C 3 18  ? 152.604 199.094 225.350 1.00 31.38  ? 18  LEU H CD1 1 
ATOM   4384 C CD2 . LEU C 3 18  ? 154.120 199.447 223.472 1.00 26.61  ? 18  LEU H CD2 1 
ATOM   4385 N N   . LYS C 3 19  ? 152.887 197.438 220.640 1.00 23.93  ? 19  LYS H N   1 
ATOM   4386 C CA  . LYS C 3 19  ? 153.525 197.909 219.429 1.00 20.73  ? 19  LYS H CA  1 
ATOM   4387 C C   . LYS C 3 19  ? 153.729 199.407 219.432 1.00 22.67  ? 19  LYS H C   1 
ATOM   4388 O O   . LYS C 3 19  ? 152.820 200.176 219.755 1.00 23.43  ? 19  LYS H O   1 
ATOM   4389 C CB  . LYS C 3 19  ? 152.716 197.498 218.214 1.00 22.75  ? 19  LYS H CB  1 
ATOM   4390 C CG  . LYS C 3 19  ? 153.325 197.894 216.893 1.00 21.97  ? 19  LYS H CG  1 
ATOM   4391 C CD  . LYS C 3 19  ? 152.533 197.348 215.755 1.00 24.49  ? 19  LYS H CD  1 
ATOM   4392 C CE  . LYS C 3 19  ? 153.153 197.698 214.443 1.00 24.01  ? 19  LYS H CE  1 
ATOM   4393 N NZ  . LYS C 3 19  ? 152.387 197.119 213.314 1.00 30.15  ? 19  LYS H NZ  1 
ATOM   4394 N N   . LEU C 3 20  ? 154.928 199.818 219.053 1.00 21.28  ? 20  LEU H N   1 
ATOM   4395 C CA  . LEU C 3 20  ? 155.257 201.219 218.913 1.00 18.81  ? 20  LEU H CA  1 
ATOM   4396 C C   . LEU C 3 20  ? 155.301 201.553 217.458 1.00 16.52  ? 20  LEU H C   1 
ATOM   4397 O O   . LEU C 3 20  ? 155.676 200.729 216.625 1.00 18.08  ? 20  LEU H O   1 
ATOM   4398 C CB  . LEU C 3 20  ? 156.628 201.566 219.497 1.00 16.75  ? 20  LEU H CB  1 
ATOM   4399 C CG  . LEU C 3 20  ? 156.876 201.227 220.930 1.00 17.45  ? 20  LEU H CG  1 
ATOM   4400 C CD1 . LEU C 3 20  ? 158.282 201.584 221.286 1.00 14.85  ? 20  LEU H CD1 1 
ATOM   4401 C CD2 . LEU C 3 20  ? 155.947 201.942 221.809 1.00 22.00  ? 20  LEU H CD2 1 
ATOM   4402 N N   . SER C 3 21  ? 155.025 202.784 217.149 1.00 18.79  ? 21  SER H N   1 
ATOM   4403 C CA  . SER C 3 21  ? 155.200 203.258 215.800 1.00 18.03  ? 21  SER H CA  1 
ATOM   4404 C C   . SER C 3 21  ? 155.672 204.694 215.898 1.00 20.60  ? 21  SER H C   1 
ATOM   4405 O O   . SER C 3 21  ? 155.462 205.330 216.938 1.00 24.10  ? 21  SER H O   1 
ATOM   4406 C CB  . SER C 3 21  ? 153.931 203.096 214.983 1.00 20.24  ? 21  SER H CB  1 
ATOM   4407 O OG  . SER C 3 21  ? 152.894 203.869 215.481 1.00 25.10  ? 21  SER H OG  1 
ATOM   4408 N N   . CYS C 3 22  ? 156.351 205.166 214.839 1.00 18.61  ? 22  CYS H N   1 
ATOM   4409 C CA  . CYS C 3 22  ? 156.943 206.487 214.692 1.00 18.69  ? 22  CYS H CA  1 
ATOM   4410 C C   . CYS C 3 22  ? 156.720 207.028 213.287 1.00 17.94  ? 22  CYS H C   1 
ATOM   4411 O O   . CYS C 3 22  ? 157.056 206.390 212.284 1.00 19.68  ? 22  CYS H O   1 
ATOM   4412 C CB  . CYS C 3 22  ? 158.451 206.400 215.013 1.00 17.24  ? 22  CYS H CB  1 
ATOM   4413 S SG  . CYS C 3 22  ? 159.410 207.914 214.843 1.00 22.22  ? 22  CYS H SG  1 
ATOM   4414 N N   . ARG C 3 23  ? 156.153 208.222 213.221 1.00 21.32  ? 23  ARG H N   1 
ATOM   4415 C CA  . ARG C 3 23  ? 155.897 208.851 211.945 1.00 21.33  ? 23  ARG H CA  1 
ATOM   4416 C C   . ARG C 3 23  ? 157.006 209.828 211.625 1.00 21.86  ? 23  ARG H C   1 
ATOM   4417 O O   . ARG C 3 23  ? 157.403 210.638 212.464 1.00 23.41  ? 23  ARG H O   1 
ATOM   4418 C CB  . ARG C 3 23  ? 154.556 209.562 211.956 1.00 25.43  ? 23  ARG H CB  1 
ATOM   4419 C CG  . ARG C 3 23  ? 154.176 210.258 210.653 1.00 29.15  ? 23  ARG H CG  1 
ATOM   4420 C CD  . ARG C 3 23  ? 153.750 209.284 209.600 1.00 29.01  ? 23  ARG H CD  1 
ATOM   4421 N NE  . ARG C 3 23  ? 153.510 209.942 208.336 1.00 32.34  ? 23  ARG H NE  1 
ATOM   4422 C CZ  . ARG C 3 23  ? 152.361 210.540 207.955 1.00 43.97  ? 23  ARG H CZ  1 
ATOM   4423 N NH1 . ARG C 3 23  ? 151.317 210.578 208.762 1.00 47.11  ? 23  ARG H NH1 1 
ATOM   4424 N NH2 . ARG C 3 23  ? 152.287 211.099 206.761 1.00 51.79  ? 23  ARG H NH2 1 
ATOM   4425 N N   . ALA C 3 24  ? 157.524 209.768 210.413 1.00 21.76  ? 24  ALA H N   1 
ATOM   4426 C CA  . ALA C 3 24  ? 158.600 210.665 210.049 1.00 20.69  ? 24  ALA H CA  1 
ATOM   4427 C C   . ALA C 3 24  ? 158.220 211.695 209.009 1.00 22.56  ? 24  ALA H C   1 
ATOM   4428 O O   . ALA C 3 24  ? 157.488 211.417 208.056 1.00 23.81  ? 24  ALA H O   1 
ATOM   4429 C CB  . ALA C 3 24  ? 159.731 209.846 209.523 1.00 19.06  ? 24  ALA H CB  1 
ATOM   4430 N N   . SER C 3 25  ? 158.807 212.878 209.146 1.00 24.88  ? 25  SER H N   1 
ATOM   4431 C CA  . SER C 3 25  ? 158.653 213.941 208.160 1.00 24.98  ? 25  SER H CA  1 
ATOM   4432 C C   . SER C 3 25  ? 159.860 214.879 208.107 1.00 25.19  ? 25  SER H C   1 
ATOM   4433 O O   . SER C 3 25  ? 160.666 214.942 209.038 1.00 28.11  ? 25  SER H O   1 
ATOM   4434 C CB  . SER C 3 25  ? 157.403 214.734 208.461 1.00 27.55  ? 25  SER H CB  1 
ATOM   4435 O OG  . SER C 3 25  ? 157.521 215.407 209.679 1.00 29.64  ? 25  SER H OG  1 
ATOM   4436 N N   . GLY C 3 26  ? 159.978 215.628 207.003 1.00 25.15  ? 26  GLY H N   1 
ATOM   4437 C CA  . GLY C 3 26  ? 161.033 216.639 206.831 1.00 26.19  ? 26  GLY H CA  1 
ATOM   4438 C C   . GLY C 3 26  ? 162.307 216.154 206.128 1.00 25.52  ? 26  GLY H C   1 
ATOM   4439 O O   . GLY C 3 26  ? 163.248 216.923 205.939 1.00 26.26  ? 26  GLY H O   1 
ATOM   4440 N N   . TYR C 3 27  ? 162.341 214.893 205.736 1.00 23.86  ? 27  TYR H N   1 
ATOM   4441 C CA  . TYR C 3 27  ? 163.503 214.316 205.078 1.00 21.77  ? 27  TYR H CA  1 
ATOM   4442 C C   . TYR C 3 27  ? 163.067 213.149 204.235 1.00 21.83  ? 27  TYR H C   1 
ATOM   4443 O O   . TYR C 3 27  ? 161.937 212.673 204.372 1.00 21.60  ? 27  TYR H O   1 
ATOM   4444 C CB  . TYR C 3 27  ? 164.544 213.894 206.108 1.00 21.84  ? 27  TYR H CB  1 
ATOM   4445 C CG  . TYR C 3 27  ? 164.138 212.752 207.006 1.00 20.78  ? 27  TYR H CG  1 
ATOM   4446 C CD1 . TYR C 3 27  ? 163.253 212.944 207.996 1.00 21.62  ? 27  TYR H CD1 1 
ATOM   4447 C CD2 . TYR C 3 27  ? 164.643 211.519 206.797 1.00 17.83  ? 27  TYR H CD2 1 
ATOM   4448 C CE1 . TYR C 3 27  ? 162.890 211.918 208.795 1.00 19.70  ? 27  TYR H CE1 1 
ATOM   4449 C CE2 . TYR C 3 27  ? 164.299 210.483 207.597 1.00 16.11  ? 27  TYR H CE2 1 
ATOM   4450 C CZ  . TYR C 3 27  ? 163.420 210.686 208.600 1.00 16.68  ? 27  TYR H CZ  1 
ATOM   4451 O OH  . TYR C 3 27  ? 163.059 209.650 209.401 1.00 15.71  ? 27  TYR H OH  1 
ATOM   4452 N N   . THR C 3 28  ? 163.946 212.660 203.371 1.00 20.48  ? 28  THR H N   1 
ATOM   4453 C CA  . THR C 3 28  ? 163.567 211.491 202.619 1.00 18.67  ? 28  THR H CA  1 
ATOM   4454 C C   . THR C 3 28  ? 163.725 210.301 203.547 1.00 17.57  ? 28  THR H C   1 
ATOM   4455 O O   . THR C 3 28  ? 164.827 209.882 203.881 1.00 19.03  ? 28  THR H O   1 
ATOM   4456 C CB  . THR C 3 28  ? 164.464 211.337 201.374 1.00 18.46  ? 28  THR H CB  1 
ATOM   4457 O OG1 . THR C 3 28  ? 164.348 212.501 200.558 1.00 22.04  ? 28  THR H OG1 1 
ATOM   4458 C CG2 . THR C 3 28  ? 164.041 210.135 200.568 1.00 19.25  ? 28  THR H CG2 1 
ATOM   4459 N N   . PHE C 3 29  ? 162.608 209.700 203.907 1.00 16.45  ? 29  PHE H N   1 
ATOM   4460 C CA  . PHE C 3 29  ? 162.575 208.614 204.874 1.00 14.36  ? 29  PHE H CA  1 
ATOM   4461 C C   . PHE C 3 29  ? 163.409 207.448 204.398 1.00 14.57  ? 29  PHE H C   1 
ATOM   4462 O O   . PHE C 3 29  ? 164.255 206.904 205.113 1.00 14.57  ? 29  PHE H O   1 
ATOM   4463 C CB  . PHE C 3 29  ? 161.131 208.219 205.113 1.00 13.76  ? 29  PHE H CB  1 
ATOM   4464 C CG  . PHE C 3 29  ? 160.908 207.162 206.083 1.00 12.45  ? 29  PHE H CG  1 
ATOM   4465 C CD1 . PHE C 3 29  ? 160.976 207.428 207.397 1.00 12.33  ? 29  PHE H CD1 1 
ATOM   4466 C CD2 . PHE C 3 29  ? 160.587 205.922 205.688 1.00 12.93  ? 29  PHE H CD2 1 
ATOM   4467 C CE1 . PHE C 3 29  ? 160.722 206.466 208.316 1.00 11.32  ? 29  PHE H CE1 1 
ATOM   4468 C CE2 . PHE C 3 29  ? 160.332 204.949 206.596 1.00 11.93  ? 29  PHE H CE2 1 
ATOM   4469 C CZ  . PHE C 3 29  ? 160.402 205.222 207.913 1.00 11.46  ? 29  PHE H CZ  1 
ATOM   4470 N N   . SER C 3 30  ? 163.214 207.113 203.145 1.00 15.08  ? 30  SER H N   1 
ATOM   4471 C CA  . SER C 3 30  ? 163.838 205.987 202.484 1.00 12.84  ? 30  SER H CA  1 
ATOM   4472 C C   . SER C 3 30  ? 165.342 206.110 202.297 1.00 13.38  ? 30  SER H C   1 
ATOM   4473 O O   . SER C 3 30  ? 165.977 205.185 201.804 1.00 14.64  ? 30  SER H O   1 
ATOM   4474 C CB  . SER C 3 30  ? 163.172 205.752 201.156 1.00 15.59  ? 30  SER H CB  1 
ATOM   4475 O OG  . SER C 3 30  ? 163.371 206.827 200.291 1.00 19.61  ? 30  SER H OG  1 
ATOM   4476 N N   . SER C 3 31  ? 165.934 207.268 202.576 1.00 15.40  ? 31  SER H N   1 
ATOM   4477 C CA  . SER C 3 31  ? 167.374 207.410 202.412 1.00 13.87  ? 31  SER H CA  1 
ATOM   4478 C C   . SER C 3 31  ? 168.150 207.053 203.678 1.00 12.33  ? 31  SER H C   1 
ATOM   4479 O O   . SER C 3 31  ? 169.388 206.984 203.668 1.00 13.66  ? 31  SER H O   1 
ATOM   4480 C CB  . SER C 3 31  ? 167.722 208.826 202.013 1.00 15.91  ? 31  SER H CB  1 
ATOM   4481 O OG  . SER C 3 31  ? 167.223 209.139 200.745 1.00 18.67  ? 31  SER H OG  1 
ATOM   4482 N N   . PHE C 3 32  ? 167.445 206.838 204.792 1.00 12.11  ? 32  PHE H N   1 
ATOM   4483 C CA  . PHE C 3 32  ? 168.121 206.602 206.058 1.00 9.81   ? 32  PHE H CA  1 
ATOM   4484 C C   . PHE C 3 32  ? 167.752 205.348 206.795 1.00 8.20   ? 32  PHE H C   1 
ATOM   4485 O O   . PHE C 3 32  ? 166.582 204.986 206.870 1.00 11.85  ? 32  PHE H O   1 
ATOM   4486 C CB  . PHE C 3 32  ? 167.779 207.708 207.032 1.00 11.02  ? 32  PHE H CB  1 
ATOM   4487 C CG  . PHE C 3 32  ? 168.244 209.047 206.698 1.00 13.18  ? 32  PHE H CG  1 
ATOM   4488 C CD1 . PHE C 3 32  ? 167.568 209.809 205.815 1.00 15.20  ? 32  PHE H CD1 1 
ATOM   4489 C CD2 . PHE C 3 32  ? 169.333 209.579 207.317 1.00 13.48  ? 32  PHE H CD2 1 
ATOM   4490 C CE1 . PHE C 3 32  ? 167.969 211.067 205.528 1.00 15.81  ? 32  PHE H CE1 1 
ATOM   4491 C CE2 . PHE C 3 32  ? 169.734 210.844 207.047 1.00 14.23  ? 32  PHE H CE2 1 
ATOM   4492 C CZ  . PHE C 3 32  ? 169.049 211.590 206.145 1.00 15.06  ? 32  PHE H CZ  1 
ATOM   4493 N N   . ALA C 3 33  ? 168.751 204.760 207.436 1.00 7.34   ? 33  ALA H N   1 
ATOM   4494 C CA  . ALA C 3 33  ? 168.556 203.657 208.364 1.00 5.38   ? 33  ALA H CA  1 
ATOM   4495 C C   . ALA C 3 33  ? 168.001 204.245 209.629 1.00 5.82   ? 33  ALA H C   1 
ATOM   4496 O O   . ALA C 3 33  ? 168.232 205.426 209.900 1.00 8.81   ? 33  ALA H O   1 
ATOM   4497 C CB  . ALA C 3 33  ? 169.838 202.911 208.650 1.00 4.25   ? 33  ALA H CB  1 
ATOM   4498 N N   . MET C 3 34  ? 167.273 203.454 210.390 1.00 6.90   ? 34  MET H N   1 
ATOM   4499 C CA  . MET C 3 34  ? 166.701 203.924 211.645 1.00 6.70   ? 34  MET H CA  1 
ATOM   4500 C C   . MET C 3 34  ? 166.848 202.933 212.760 1.00 6.20   ? 34  MET H C   1 
ATOM   4501 O O   . MET C 3 34  ? 167.061 201.750 212.533 1.00 6.79   ? 34  MET H O   1 
ATOM   4502 C CB  . MET C 3 34  ? 165.260 204.315 211.491 1.00 8.60   ? 34  MET H CB  1 
ATOM   4503 C CG  . MET C 3 34  ? 165.032 205.443 210.540 1.00 8.26   ? 34  MET H CG  1 
ATOM   4504 S SD  . MET C 3 34  ? 163.400 205.968 210.515 1.00 11.19  ? 34  MET H SD  1 
ATOM   4505 C CE  . MET C 3 34  ? 163.316 207.030 211.955 1.00 11.96  ? 34  MET H CE  1 
ATOM   4506 N N   . SER C 3 35  ? 166.728 203.411 213.975 1.00 8.20   ? 35  SER H N   1 
ATOM   4507 C CA  . SER C 3 35  ? 166.885 202.566 215.132 1.00 8.45   ? 35  SER H CA  1 
ATOM   4508 C C   . SER C 3 35  ? 166.018 202.958 216.305 1.00 7.97   ? 35  SER H C   1 
ATOM   4509 O O   . SER C 3 35  ? 165.411 204.034 216.340 1.00 9.55   ? 35  SER H O   1 
ATOM   4510 C CB  . SER C 3 35  ? 168.322 202.649 215.591 1.00 7.47   ? 35  SER H CB  1 
ATOM   4511 O OG  . SER C 3 35  ? 168.588 203.923 216.059 1.00 9.40   ? 35  SER H OG  1 
ATOM   4512 N N   . TRP C 3 36  ? 165.931 202.042 217.261 1.00 8.98   ? 36  TRP H N   1 
ATOM   4513 C CA  . TRP C 3 36  ? 165.272 202.328 218.515 1.00 9.28   ? 36  TRP H CA  1 
ATOM   4514 C C   . TRP C 3 36  ? 166.317 202.300 219.614 1.00 9.00   ? 36  TRP H C   1 
ATOM   4515 O O   . TRP C 3 36  ? 167.118 201.355 219.711 1.00 9.70   ? 36  TRP H O   1 
ATOM   4516 C CB  . TRP C 3 36  ? 164.134 201.341 218.832 1.00 8.92   ? 36  TRP H CB  1 
ATOM   4517 C CG  . TRP C 3 36  ? 162.920 201.482 217.941 1.00 8.48   ? 36  TRP H CG  1 
ATOM   4518 C CD1 . TRP C 3 36  ? 162.677 200.793 216.833 1.00 8.22   ? 36  TRP H CD1 1 
ATOM   4519 C CD2 . TRP C 3 36  ? 161.797 202.371 218.100 1.00 9.08   ? 36  TRP H CD2 1 
ATOM   4520 N NE1 . TRP C 3 36  ? 161.498 201.175 216.278 1.00 9.05   ? 36  TRP H NE1 1 
ATOM   4521 C CE2 . TRP C 3 36  ? 160.950 202.141 217.037 1.00 8.54   ? 36  TRP H CE2 1 
ATOM   4522 C CE3 . TRP C 3 36  ? 161.457 203.319 219.038 1.00 10.49  ? 36  TRP H CE3 1 
ATOM   4523 C CZ2 . TRP C 3 36  ? 159.774 202.826 216.879 1.00 11.20  ? 36  TRP H CZ2 1 
ATOM   4524 C CZ3 . TRP C 3 36  ? 160.282 204.009 218.883 1.00 11.74  ? 36  TRP H CZ3 1 
ATOM   4525 C CH2 . TRP C 3 36  ? 159.461 203.767 217.829 1.00 12.28  ? 36  TRP H CH2 1 
ATOM   4526 N N   . VAL C 3 37  ? 166.275 203.330 220.450 1.00 11.20  ? 37  VAL H N   1 
ATOM   4527 C CA  . VAL C 3 37  ? 167.163 203.489 221.599 1.00 11.96  ? 37  VAL H CA  1 
ATOM   4528 C C   . VAL C 3 37  ? 166.299 203.596 222.841 1.00 12.58  ? 37  VAL H C   1 
ATOM   4529 O O   . VAL C 3 37  ? 165.316 204.322 222.880 1.00 14.55  ? 37  VAL H O   1 
ATOM   4530 C CB  . VAL C 3 37  ? 168.096 204.714 221.443 1.00 11.57  ? 37  VAL H CB  1 
ATOM   4531 C CG1 . VAL C 3 37  ? 168.985 204.872 222.697 1.00 12.75  ? 37  VAL H CG1 1 
ATOM   4532 C CG2 . VAL C 3 37  ? 168.982 204.542 220.190 1.00 8.59   ? 37  VAL H CG2 1 
ATOM   4533 N N   . ARG C 3 38  ? 166.619 202.826 223.839 1.00 14.63  ? 38  ARG H N   1 
ATOM   4534 C CA  . ARG C 3 38  ? 165.837 202.767 225.045 1.00 15.08  ? 38  ARG H CA  1 
ATOM   4535 C C   . ARG C 3 38  ? 166.469 203.451 226.251 1.00 16.60  ? 38  ARG H C   1 
ATOM   4536 O O   . ARG C 3 38  ? 167.677 203.395 226.448 1.00 17.44  ? 38  ARG H O   1 
ATOM   4537 C CB  . ARG C 3 38  ? 165.603 201.306 225.303 1.00 15.99  ? 38  ARG H CB  1 
ATOM   4538 C CG  . ARG C 3 38  ? 164.798 200.999 226.380 1.00 16.82  ? 38  ARG H CG  1 
ATOM   4539 C CD  . ARG C 3 38  ? 164.478 199.579 226.448 1.00 18.02  ? 38  ARG H CD  1 
ATOM   4540 N NE  . ARG C 3 38  ? 165.553 198.728 226.786 1.00 19.15  ? 38  ARG H NE  1 
ATOM   4541 C CZ  . ARG C 3 38  ? 165.400 197.400 226.907 1.00 20.95  ? 38  ARG H CZ  1 
ATOM   4542 N NH1 . ARG C 3 38  ? 164.205 196.861 226.689 1.00 21.42  ? 38  ARG H NH1 1 
ATOM   4543 N NH2 . ARG C 3 38  ? 166.429 196.659 227.262 1.00 23.12  ? 38  ARG H NH2 1 
ATOM   4544 N N   . GLN C 3 39  ? 165.654 204.090 227.080 1.00 17.71  ? 39  GLN H N   1 
ATOM   4545 C CA  . GLN C 3 39  ? 166.165 204.656 228.324 1.00 18.51  ? 39  GLN H CA  1 
ATOM   4546 C C   . GLN C 3 39  ? 165.326 204.315 229.548 1.00 22.45  ? 39  GLN H C   1 
ATOM   4547 O O   . GLN C 3 39  ? 164.212 204.817 229.714 1.00 23.03  ? 39  GLN H O   1 
ATOM   4548 C CB  . GLN C 3 39  ? 166.271 206.154 228.179 1.00 19.14  ? 39  GLN H CB  1 
ATOM   4549 C CG  . GLN C 3 39  ? 166.825 206.845 229.364 1.00 20.33  ? 39  GLN H CG  1 
ATOM   4550 C CD  . GLN C 3 39  ? 167.206 208.244 229.048 1.00 19.74  ? 39  GLN H CD  1 
ATOM   4551 O OE1 . GLN C 3 39  ? 166.586 208.925 228.198 1.00 21.63  ? 39  GLN H OE1 1 
ATOM   4552 N NE2 . GLN C 3 39  ? 168.252 208.711 229.705 1.00 20.35  ? 39  GLN H NE2 1 
ATOM   4553 N N   . ALA C 3 40  ? 165.851 203.472 230.429 1.00 24.45  ? 40  ALA H N   1 
ATOM   4554 C CA  . ALA C 3 40  ? 165.084 203.082 231.603 1.00 27.94  ? 40  ALA H CA  1 
ATOM   4555 C C   . ALA C 3 40  ? 164.914 204.348 232.422 1.00 31.55  ? 40  ALA H C   1 
ATOM   4556 O O   . ALA C 3 40  ? 165.776 205.215 232.330 1.00 33.20  ? 40  ALA H O   1 
ATOM   4557 C CB  . ALA C 3 40  ? 165.765 201.974 232.367 1.00 30.42  ? 40  ALA H CB  1 
ATOM   4558 N N   . PRO C 3 41  ? 163.871 204.507 233.250 1.00 33.73  ? 41  PRO H N   1 
ATOM   4559 C CA  . PRO C 3 41  ? 163.614 205.713 234.024 1.00 35.49  ? 41  PRO H CA  1 
ATOM   4560 C C   . PRO C 3 41  ? 164.798 206.272 234.823 1.00 38.66  ? 41  PRO H C   1 
ATOM   4561 O O   . PRO C 3 41  ? 164.918 207.487 234.963 1.00 38.65  ? 41  PRO H O   1 
ATOM   4562 C CB  . PRO C 3 41  ? 162.519 205.230 234.980 1.00 38.71  ? 41  PRO H CB  1 
ATOM   4563 C CG  . PRO C 3 41  ? 161.789 204.157 234.210 1.00 35.62  ? 41  PRO H CG  1 
ATOM   4564 C CD  . PRO C 3 41  ? 162.867 203.428 233.464 1.00 32.19  ? 41  PRO H CD  1 
ATOM   4565 N N   . GLY C 3 42  ? 165.661 205.408 235.357 1.00 38.33  ? 42  GLY H N   1 
ATOM   4566 C CA  . GLY C 3 42  ? 166.810 205.869 236.131 1.00 40.05  ? 42  GLY H CA  1 
ATOM   4567 C C   . GLY C 3 42  ? 168.161 205.628 235.453 1.00 40.16  ? 42  GLY H C   1 
ATOM   4568 O O   . GLY C 3 42  ? 169.196 205.670 236.122 1.00 42.03  ? 42  GLY H O   1 
ATOM   4569 N N   . LYS C 3 43  ? 168.161 205.284 234.170 1.00 36.18  ? 43  LYS H N   1 
ATOM   4570 C CA  . LYS C 3 43  ? 169.401 204.919 233.486 1.00 35.85  ? 43  LYS H CA  1 
ATOM   4571 C C   . LYS C 3 43  ? 169.773 205.785 232.284 1.00 30.21  ? 43  LYS H C   1 
ATOM   4572 O O   . LYS C 3 43  ? 169.133 206.795 231.979 1.00 29.35  ? 43  LYS H O   1 
ATOM   4573 C CB  . LYS C 3 43  ? 169.336 203.456 233.060 1.00 35.48  ? 43  LYS H CB  1 
ATOM   4574 C CG  . LYS C 3 43  ? 169.086 202.449 234.204 1.00 41.17  ? 43  LYS H CG  1 
ATOM   4575 C CD  . LYS C 3 43  ? 170.257 202.364 235.182 1.00 47.78  ? 43  LYS H CD  1 
ATOM   4576 C CE  . LYS C 3 43  ? 170.025 201.282 236.227 1.00 52.86  ? 43  LYS H CE  1 
ATOM   4577 N NZ  . LYS C 3 43  ? 171.136 201.217 237.226 1.00 56.78  ? 43  LYS H NZ  1 
ATOM   4578 N N   . GLY C 3 44  ? 170.862 205.386 231.626 1.00 28.46  ? 44  GLY H N   1 
ATOM   4579 C CA  . GLY C 3 44  ? 171.350 206.054 230.437 1.00 22.68  ? 44  GLY H CA  1 
ATOM   4580 C C   . GLY C 3 44  ? 170.723 205.412 229.220 1.00 20.67  ? 44  GLY H C   1 
ATOM   4581 O O   . GLY C 3 44  ? 169.685 204.773 229.333 1.00 22.39  ? 44  GLY H O   1 
ATOM   4582 N N   . LEU C 3 45  ? 171.321 205.605 228.069 1.00 17.89  ? 45  LEU H N   1 
ATOM   4583 C CA  . LEU C 3 45  ? 170.752 205.120 226.832 1.00 15.24  ? 45  LEU H CA  1 
ATOM   4584 C C   . LEU C 3 45  ? 171.240 203.715 226.501 1.00 15.30  ? 45  LEU H C   1 
ATOM   4585 O O   . LEU C 3 45  ? 172.401 203.395 226.735 1.00 16.83  ? 45  LEU H O   1 
ATOM   4586 C CB  . LEU C 3 45  ? 171.189 206.089 225.745 1.00 14.62  ? 45  LEU H CB  1 
ATOM   4587 C CG  . LEU C 3 45  ? 170.804 207.576 225.941 1.00 14.02  ? 45  LEU H CG  1 
ATOM   4588 C CD1 . LEU C 3 45  ? 171.464 208.390 224.864 1.00 13.66  ? 45  LEU H CD1 1 
ATOM   4589 C CD2 . LEU C 3 45  ? 169.310 207.753 225.901 1.00 14.97  ? 45  LEU H CD2 1 
ATOM   4590 N N   . GLU C 3 46  ? 170.381 202.907 225.889 1.00 15.18  ? 46  GLU H N   1 
ATOM   4591 C CA  . GLU C 3 46  ? 170.738 201.574 225.425 1.00 14.64  ? 46  GLU H CA  1 
ATOM   4592 C C   . GLU C 3 46  ? 170.271 201.340 223.995 1.00 13.57  ? 46  GLU H C   1 
ATOM   4593 O O   . GLU C 3 46  ? 169.133 201.607 223.639 1.00 13.81  ? 46  GLU H O   1 
ATOM   4594 C CB  . GLU C 3 46  ? 170.099 200.523 226.334 1.00 17.57  ? 46  GLU H CB  1 
ATOM   4595 C CG  . GLU C 3 46  ? 170.455 199.084 225.997 1.00 20.13  ? 46  GLU H CG  1 
ATOM   4596 C CD  . GLU C 3 46  ? 169.821 198.070 226.897 1.00 24.32  ? 46  GLU H CD  1 
ATOM   4597 O OE1 . GLU C 3 46  ? 168.931 198.407 227.635 1.00 25.68  ? 46  GLU H OE1 1 
ATOM   4598 O OE2 . GLU C 3 46  ? 170.233 196.945 226.858 1.00 26.34  ? 46  GLU H OE2 1 
ATOM   4599 N N   . TRP C 3 47  ? 171.120 200.826 223.139 1.00 13.13  ? 47  TRP H N   1 
ATOM   4600 C CA  . TRP C 3 47  ? 170.640 200.538 221.797 1.00 9.78   ? 47  TRP H CA  1 
ATOM   4601 C C   . TRP C 3 47  ? 169.814 199.266 221.809 1.00 10.19  ? 47  TRP H C   1 
ATOM   4602 O O   . TRP C 3 47  ? 170.235 198.278 222.399 1.00 12.35  ? 47  TRP H O   1 
ATOM   4603 C CB  . TRP C 3 47  ? 171.819 200.447 220.848 1.00 9.02   ? 47  TRP H CB  1 
ATOM   4604 C CG  . TRP C 3 47  ? 171.486 199.996 219.516 1.00 7.07   ? 47  TRP H CG  1 
ATOM   4605 C CD1 . TRP C 3 47  ? 171.008 200.723 218.508 1.00 6.24   ? 47  TRP H CD1 1 
ATOM   4606 C CD2 . TRP C 3 47  ? 171.644 198.670 219.014 1.00 7.02   ? 47  TRP H CD2 1 
ATOM   4607 N NE1 . TRP C 3 47  ? 170.848 199.951 217.427 1.00 6.15   ? 47  TRP H NE1 1 
ATOM   4608 C CE2 . TRP C 3 47  ? 171.237 198.686 217.725 1.00 5.96   ? 47  TRP H CE2 1 
ATOM   4609 C CE3 . TRP C 3 47  ? 172.094 197.496 219.561 1.00 7.52   ? 47  TRP H CE3 1 
ATOM   4610 C CZ2 . TRP C 3 47  ? 171.259 197.562 216.953 1.00 5.81   ? 47  TRP H CZ2 1 
ATOM   4611 C CZ3 . TRP C 3 47  ? 172.111 196.383 218.789 1.00 7.34   ? 47  TRP H CZ3 1 
ATOM   4612 C CH2 . TRP C 3 47  ? 171.699 196.419 217.515 1.00 6.30   ? 47  TRP H CH2 1 
ATOM   4613 N N   . VAL C 3 48  ? 168.666 199.263 221.126 1.00 9.94   ? 48  VAL H N   1 
ATOM   4614 C CA  . VAL C 3 48  ? 167.836 198.071 221.073 1.00 9.31   ? 48  VAL H CA  1 
ATOM   4615 C C   . VAL C 3 48  ? 167.795 197.420 219.702 1.00 7.91   ? 48  VAL H C   1 
ATOM   4616 O O   . VAL C 3 48  ? 167.982 196.207 219.578 1.00 9.72   ? 48  VAL H O   1 
ATOM   4617 C CB  . VAL C 3 48  ? 166.404 198.417 221.523 1.00 10.88  ? 48  VAL H CB  1 
ATOM   4618 C CG1 . VAL C 3 48  ? 165.485 197.235 221.409 1.00 12.98  ? 48  VAL H CG1 1 
ATOM   4619 C CG2 . VAL C 3 48  ? 166.438 198.863 222.933 1.00 12.92  ? 48  VAL H CG2 1 
ATOM   4620 N N   . SER C 3 49  ? 167.494 198.201 218.674 1.00 7.77   ? 49  SER H N   1 
ATOM   4621 C CA  . SER C 3 49  ? 167.385 197.613 217.342 1.00 6.76   ? 49  SER H CA  1 
ATOM   4622 C C   . SER C 3 49  ? 167.693 198.575 216.210 1.00 6.32   ? 49  SER H C   1 
ATOM   4623 O O   . SER C 3 49  ? 167.524 199.784 216.325 1.00 8.10   ? 49  SER H O   1 
ATOM   4624 C CB  . SER C 3 49  ? 166.013 197.018 217.165 1.00 8.68   ? 49  SER H CB  1 
ATOM   4625 O OG  . SER C 3 49  ? 165.033 198.001 217.215 1.00 11.32  ? 49  SER H OG  1 
ATOM   4626 N N   . LEU C 3 50  ? 168.106 198.015 215.079 1.00 6.33   ? 50  LEU H N   1 
ATOM   4627 C CA  . LEU C 3 50  ? 168.461 198.754 213.862 1.00 5.18   ? 50  LEU H CA  1 
ATOM   4628 C C   . LEU C 3 50  ? 167.882 198.166 212.599 1.00 4.51   ? 50  LEU H C   1 
ATOM   4629 O O   . LEU C 3 50  ? 167.924 196.957 212.392 1.00 5.72   ? 50  LEU H O   1 
ATOM   4630 C CB  . LEU C 3 50  ? 169.991 198.782 213.753 1.00 5.89   ? 50  LEU H CB  1 
ATOM   4631 C CG  . LEU C 3 50  ? 170.693 199.349 212.522 1.00 4.03   ? 50  LEU H CG  1 
ATOM   4632 C CD1 . LEU C 3 50  ? 170.475 200.846 212.383 1.00 4.39   ? 50  LEU H CD1 1 
ATOM   4633 C CD2 . LEU C 3 50  ? 172.158 199.024 212.680 1.00 4.21   ? 50  LEU H CD2 1 
ATOM   4634 N N   . ILE C 3 51  ? 167.323 199.017 211.752 1.00 5.43   ? 51  ILE H N   1 
ATOM   4635 C CA  . ILE C 3 51  ? 166.809 198.574 210.475 1.00 4.48   ? 51  ILE H CA  1 
ATOM   4636 C C   . ILE C 3 51  ? 167.354 199.402 209.319 1.00 4.60   ? 51  ILE H C   1 
ATOM   4637 O O   . ILE C 3 51  ? 167.448 200.630 209.369 1.00 6.30   ? 51  ILE H O   1 
ATOM   4638 C CB  . ILE C 3 51  ? 165.264 198.563 210.465 1.00 6.32   ? 51  ILE H CB  1 
ATOM   4639 C CG1 . ILE C 3 51  ? 164.734 197.918 209.196 1.00 5.54   ? 51  ILE H CG1 1 
ATOM   4640 C CG2 . ILE C 3 51  ? 164.720 199.982 210.579 1.00 7.32   ? 51  ILE H CG2 1 
ATOM   4641 C CD1 . ILE C 3 51  ? 163.316 197.522 209.289 1.00 6.77   ? 51  ILE H CD1 1 
ATOM   4642 N N   . ASN C 3 52  ? 167.616 198.704 208.246 1.00 4.87   ? 52  ASN H N   1 
ATOM   4643 C CA  . ASN C 3 52  ? 168.082 199.195 206.964 1.00 4.59   ? 52  ASN H CA  1 
ATOM   4644 C C   . ASN C 3 52  ? 167.099 200.108 206.278 1.00 4.94   ? 52  ASN H C   1 
ATOM   4645 O O   . ASN C 3 52  ? 165.895 199.931 206.399 1.00 8.63   ? 52  ASN H O   1 
ATOM   4646 C CB  . ASN C 3 52  ? 168.346 197.991 206.107 1.00 2.77   ? 52  ASN H CB  1 
ATOM   4647 C CG  . ASN C 3 52  ? 169.020 198.228 204.888 1.00 0.60   ? 52  ASN H CG  1 
ATOM   4648 O OD1 . ASN C 3 52  ? 168.433 198.609 203.885 1.00 4.64   ? 52  ASN H OD1 1 
ATOM   4649 N ND2 . ASN C 3 52  ? 170.269 198.016 204.901 1.00 4.07   ? 52  ASN H ND2 1 
ATOM   4650 N N   . ASP C 3 53  A 167.593 201.036 205.481 1.00 5.29   ? 52  ASP H N   1 
ATOM   4651 C CA  . ASP C 3 53  A 166.740 201.958 204.747 1.00 5.44   ? 52  ASP H CA  1 
ATOM   4652 C C   . ASP C 3 53  A 165.771 201.305 203.757 1.00 6.52   ? 52  ASP H C   1 
ATOM   4653 O O   . ASP C 3 53  A 164.712 201.867 203.459 1.00 8.69   ? 52  ASP H O   1 
ATOM   4654 C CB  . ASP C 3 53  A 167.634 202.939 204.042 1.00 7.51   ? 52  ASP H CB  1 
ATOM   4655 C CG  . ASP C 3 53  A 168.642 202.234 203.285 1.00 7.81   ? 52  ASP H CG  1 
ATOM   4656 O OD1 . ASP C 3 53  A 169.541 201.728 203.946 1.00 8.04   ? 52  ASP H OD1 1 
ATOM   4657 O OD2 . ASP C 3 53  A 168.547 202.125 202.104 1.00 2.92   ? 52  ASP H OD2 1 
ATOM   4658 N N   . ARG C 3 54  ? 166.090 200.108 203.282 1.00 5.89   ? 53  ARG H N   1 
ATOM   4659 C CA  . ARG C 3 54  ? 165.236 199.386 202.364 1.00 4.46   ? 53  ARG H CA  1 
ATOM   4660 C C   . ARG C 3 54  ? 164.342 198.389 203.107 1.00 5.66   ? 53  ARG H C   1 
ATOM   4661 O O   . ARG C 3 54  ? 163.533 197.700 202.495 1.00 9.40   ? 53  ARG H O   1 
ATOM   4662 C CB  . ARG C 3 54  ? 166.096 198.633 201.372 1.00 0.04   ? 53  ARG H CB  1 
ATOM   4663 C CG  . ARG C 3 54  ? 166.899 199.503 200.428 1.00 1.35   ? 53  ARG H CG  1 
ATOM   4664 C CD  . ARG C 3 54  ? 167.720 198.710 199.474 1.00 0.00   ? 53  ARG H CD  1 
ATOM   4665 N NE  . ARG C 3 54  ? 168.804 198.017 200.183 1.00 0.01   ? 53  ARG H NE  1 
ATOM   4666 C CZ  . ARG C 3 54  ? 168.837 196.705 200.460 1.00 1.56   ? 53  ARG H CZ  1 
ATOM   4667 N NH1 . ARG C 3 54  ? 167.892 195.878 200.074 1.00 2.66   ? 53  ARG H NH1 1 
ATOM   4668 N NH2 . ARG C 3 54  ? 169.810 196.215 201.154 1.00 0.70   ? 53  ARG H NH2 1 
ATOM   4669 N N   . GLY C 3 55  ? 164.553 198.248 204.415 1.00 5.82   ? 54  GLY H N   1 
ATOM   4670 C CA  . GLY C 3 55  ? 163.806 197.348 205.291 1.00 5.93   ? 54  GLY H CA  1 
ATOM   4671 C C   . GLY C 3 55  ? 164.235 195.872 205.317 1.00 6.09   ? 54  GLY H C   1 
ATOM   4672 O O   . GLY C 3 55  ? 163.644 195.073 206.039 1.00 8.15   ? 54  GLY H O   1 
ATOM   4673 N N   . GLY C 3 56  ? 165.231 195.494 204.524 1.00 6.56   ? 55  GLY H N   1 
ATOM   4674 C CA  . GLY C 3 56  ? 165.659 194.094 204.432 1.00 5.37   ? 55  GLY H CA  1 
ATOM   4675 C C   . GLY C 3 56  ? 166.542 193.540 205.545 1.00 5.24   ? 55  GLY H C   1 
ATOM   4676 O O   . GLY C 3 56  ? 166.564 192.332 205.777 1.00 6.98   ? 55  GLY H O   1 
ATOM   4677 N N   . LEU C 3 57  ? 167.291 194.391 206.218 1.00 5.06   ? 56  LEU H N   1 
ATOM   4678 C CA  . LEU C 3 57  ? 168.228 193.924 207.222 1.00 3.73   ? 56  LEU H CA  1 
ATOM   4679 C C   . LEU C 3 57  ? 167.925 194.492 208.576 1.00 3.65   ? 56  LEU H C   1 
ATOM   4680 O O   . LEU C 3 57  ? 167.807 195.709 208.748 1.00 5.46   ? 56  LEU H O   1 
ATOM   4681 C CB  . LEU C 3 57  ? 169.658 194.316 206.826 1.00 4.24   ? 56  LEU H CB  1 
ATOM   4682 C CG  . LEU C 3 57  ? 170.166 193.831 205.467 1.00 3.75   ? 56  LEU H CG  1 
ATOM   4683 C CD1 . LEU C 3 57  ? 171.492 194.485 205.168 1.00 1.59   ? 56  LEU H CD1 1 
ATOM   4684 C CD2 . LEU C 3 57  ? 170.318 192.347 205.492 1.00 2.29   ? 56  LEU H CD2 1 
ATOM   4685 N N   . THR C 3 58  ? 167.811 193.605 209.553 1.00 4.50   ? 57  THR H N   1 
ATOM   4686 C CA  . THR C 3 58  ? 167.533 194.012 210.916 1.00 4.77   ? 57  THR H CA  1 
ATOM   4687 C C   . THR C 3 58  ? 168.543 193.452 211.887 1.00 4.98   ? 57  THR H C   1 
ATOM   4688 O O   . THR C 3 58  ? 168.966 192.303 211.757 1.00 6.64   ? 57  THR H O   1 
ATOM   4689 C CB  . THR C 3 58  ? 166.161 193.519 211.338 1.00 5.47   ? 57  THR H CB  1 
ATOM   4690 O OG1 . THR C 3 58  ? 166.141 192.094 211.239 1.00 0.00   ? 57  THR H OG1 1 
ATOM   4691 C CG2 . THR C 3 58  ? 165.100 194.100 210.447 1.00 5.25   ? 57  THR H CG2 1 
ATOM   4692 N N   . PHE C 3 59  ? 168.849 194.231 212.920 1.00 5.36   ? 58  PHE H N   1 
ATOM   4693 C CA  . PHE C 3 59  ? 169.796 193.819 213.940 1.00 5.27   ? 58  PHE H CA  1 
ATOM   4694 C C   . PHE C 3 59  ? 169.221 194.104 215.315 1.00 6.64   ? 58  PHE H C   1 
ATOM   4695 O O   . PHE C 3 59  ? 168.537 195.112 215.501 1.00 7.14   ? 58  PHE H O   1 
ATOM   4696 C CB  . PHE C 3 59  ? 171.084 194.604 213.744 1.00 5.27   ? 58  PHE H CB  1 
ATOM   4697 C CG  . PHE C 3 59  ? 171.614 194.487 212.352 1.00 4.95   ? 58  PHE H CG  1 
ATOM   4698 C CD1 . PHE C 3 59  ? 172.386 193.447 211.948 1.00 5.31   ? 58  PHE H CD1 1 
ATOM   4699 C CD2 . PHE C 3 59  ? 171.281 195.444 211.421 1.00 4.37   ? 58  PHE H CD2 1 
ATOM   4700 C CE1 . PHE C 3 59  ? 172.820 193.366 210.656 1.00 4.00   ? 58  PHE H CE1 1 
ATOM   4701 C CE2 . PHE C 3 59  ? 171.711 195.355 210.144 1.00 3.91   ? 58  PHE H CE2 1 
ATOM   4702 C CZ  . PHE C 3 59  ? 172.477 194.324 209.760 1.00 3.12   ? 58  PHE H CZ  1 
ATOM   4703 N N   . TYR C 3 60  ? 169.530 193.257 216.295 1.00 9.09   ? 59  TYR H N   1 
ATOM   4704 C CA  . TYR C 3 60  ? 169.019 193.442 217.656 1.00 9.38   ? 59  TYR H CA  1 
ATOM   4705 C C   . TYR C 3 60  ? 170.062 193.275 218.724 1.00 11.36  ? 59  TYR H C   1 
ATOM   4706 O O   . TYR C 3 60  ? 171.047 192.564 218.526 1.00 14.46  ? 59  TYR H O   1 
ATOM   4707 C CB  . TYR C 3 60  ? 167.932 192.424 217.952 1.00 11.93  ? 59  TYR H CB  1 
ATOM   4708 C CG  . TYR C 3 60  ? 166.804 192.491 217.034 1.00 10.47  ? 59  TYR H CG  1 
ATOM   4709 C CD1 . TYR C 3 60  ? 165.759 193.326 217.282 1.00 10.06  ? 59  TYR H CD1 1 
ATOM   4710 C CD2 . TYR C 3 60  ? 166.825 191.722 215.908 1.00 8.94   ? 59  TYR H CD2 1 
ATOM   4711 C CE1 . TYR C 3 60  ? 164.744 193.396 216.393 1.00 8.88   ? 59  TYR H CE1 1 
ATOM   4712 C CE2 . TYR C 3 60  ? 165.815 191.790 215.026 1.00 7.50   ? 59  TYR H CE2 1 
ATOM   4713 C CZ  . TYR C 3 60  ? 164.784 192.619 215.260 1.00 7.99   ? 59  TYR H CZ  1 
ATOM   4714 O OH  . TYR C 3 60  ? 163.780 192.675 214.364 1.00 10.35  ? 59  TYR H OH  1 
ATOM   4715 N N   . VAL C 3 61  ? 169.830 193.911 219.862 1.00 12.25  ? 60  VAL H N   1 
ATOM   4716 C CA  . VAL C 3 61  ? 170.620 193.668 221.049 1.00 13.94  ? 60  VAL H CA  1 
ATOM   4717 C C   . VAL C 3 61  ? 170.197 192.295 221.539 1.00 18.92  ? 60  VAL H C   1 
ATOM   4718 O O   . VAL C 3 61  ? 169.008 191.985 221.539 1.00 23.15  ? 60  VAL H O   1 
ATOM   4719 C CB  . VAL C 3 61  ? 170.415 194.775 222.106 1.00 13.45  ? 60  VAL H CB  1 
ATOM   4720 C CG1 . VAL C 3 61  ? 169.032 194.766 222.666 1.00 15.30  ? 60  VAL H CG1 1 
ATOM   4721 C CG2 . VAL C 3 61  ? 171.399 194.611 223.209 1.00 16.56  ? 60  VAL H CG2 1 
ATOM   4722 N N   . ASP C 3 62  ? 171.130 191.494 222.038 1.00 22.28  ? 61  ASP H N   1 
ATOM   4723 C CA  . ASP C 3 62  ? 170.796 190.140 222.474 1.00 21.94  ? 61  ASP H CA  1 
ATOM   4724 C C   . ASP C 3 62  ? 169.638 190.038 223.448 1.00 23.23  ? 61  ASP H C   1 
ATOM   4725 O O   . ASP C 3 62  ? 168.815 189.131 223.333 1.00 24.52  ? 61  ASP H O   1 
ATOM   4726 C CB  . ASP C 3 62  ? 172.005 189.493 223.134 1.00 28.54  ? 61  ASP H CB  1 
ATOM   4727 C CG  . ASP C 3 62  ? 173.108 189.059 222.164 1.00 34.78  ? 61  ASP H CG  1 
ATOM   4728 O OD1 . ASP C 3 62  ? 172.862 188.916 220.970 1.00 32.10  ? 61  ASP H OD1 1 
ATOM   4729 O OD2 . ASP C 3 62  ? 174.202 188.896 222.621 1.00 41.41  ? 61  ASP H OD2 1 
ATOM   4730 N N   . SER C 3 63  ? 169.482 190.987 224.342 1.00 22.51  ? 62  SER H N   1 
ATOM   4731 C CA  . SER C 3 63  ? 168.434 190.895 225.343 1.00 21.33  ? 62  SER H CA  1 
ATOM   4732 C C   . SER C 3 63  ? 166.996 190.917 224.811 1.00 21.64  ? 62  SER H C   1 
ATOM   4733 O O   . SER C 3 63  ? 166.075 190.578 225.563 1.00 25.06  ? 62  SER H O   1 
ATOM   4734 C CB  . SER C 3 63  ? 168.625 191.990 226.370 1.00 21.33  ? 62  SER H CB  1 
ATOM   4735 O OG  . SER C 3 63  ? 168.424 193.259 225.824 1.00 23.28  ? 62  SER H OG  1 
ATOM   4736 N N   . VAL C 3 64  ? 166.785 191.329 223.552 1.00 21.92  ? 63  VAL H N   1 
ATOM   4737 C CA  . VAL C 3 64  ? 165.446 191.373 222.961 1.00 20.63  ? 63  VAL H CA  1 
ATOM   4738 C C   . VAL C 3 64  ? 165.419 190.573 221.665 1.00 20.37  ? 63  VAL H C   1 
ATOM   4739 O O   . VAL C 3 64  ? 164.461 190.642 220.892 1.00 20.69  ? 63  VAL H O   1 
ATOM   4740 C CB  . VAL C 3 64  ? 165.039 192.801 222.588 1.00 19.41  ? 63  VAL H CB  1 
ATOM   4741 C CG1 . VAL C 3 64  ? 165.078 193.676 223.814 1.00 20.42  ? 63  VAL H CG1 1 
ATOM   4742 C CG2 . VAL C 3 64  ? 165.881 193.316 221.454 1.00 17.00  ? 63  VAL H CG2 1 
ATOM   4743 N N   . LYS C 3 65  ? 166.505 189.891 221.356 1.00 21.36  ? 64  LYS H N   1 
ATOM   4744 C CA  . LYS C 3 65  ? 166.662 189.319 220.025 1.00 21.13  ? 64  LYS H CA  1 
ATOM   4745 C C   . LYS C 3 65  ? 165.578 188.361 219.588 1.00 24.23  ? 64  LYS H C   1 
ATOM   4746 O O   . LYS C 3 65  ? 165.223 188.325 218.415 1.00 23.50  ? 64  LYS H O   1 
ATOM   4747 C CB  . LYS C 3 65  ? 168.033 188.693 219.919 1.00 22.69  ? 64  LYS H CB  1 
ATOM   4748 C CG  . LYS C 3 65  ? 168.429 188.181 218.540 1.00 22.15  ? 64  LYS H CG  1 
ATOM   4749 C CD  . LYS C 3 65  ? 169.883 187.699 218.551 1.00 27.32  ? 64  LYS H CD  1 
ATOM   4750 C CE  . LYS C 3 65  ? 170.888 188.881 218.508 1.00 25.94  ? 64  LYS H CE  1 
ATOM   4751 N NZ  . LYS C 3 65  ? 172.299 188.422 218.574 1.00 30.66  ? 64  LYS H NZ  1 
ATOM   4752 N N   . GLY C 3 66  ? 165.065 187.553 220.493 1.00 24.15  ? 65  GLY H N   1 
ATOM   4753 C CA  . GLY C 3 66  ? 164.018 186.616 220.117 1.00 23.70  ? 65  GLY H CA  1 
ATOM   4754 C C   . GLY C 3 66  ? 162.628 187.147 220.451 1.00 23.83  ? 65  GLY H C   1 
ATOM   4755 O O   . GLY C 3 66  ? 161.653 186.399 220.402 1.00 26.84  ? 65  GLY H O   1 
ATOM   4756 N N   . ARG C 3 67  ? 162.539 188.407 220.875 1.00 23.55  ? 66  ARG H N   1 
ATOM   4757 C CA  . ARG C 3 67  ? 161.272 188.945 221.332 1.00 21.68  ? 66  ARG H CA  1 
ATOM   4758 C C   . ARG C 3 67  ? 160.765 190.150 220.553 1.00 21.70  ? 66  ARG H C   1 
ATOM   4759 O O   . ARG C 3 67  ? 159.561 190.396 220.494 1.00 22.67  ? 66  ARG H O   1 
ATOM   4760 C CB  . ARG C 3 67  ? 161.428 189.331 222.772 1.00 23.66  ? 66  ARG H CB  1 
ATOM   4761 C CG  . ARG C 3 67  ? 161.723 188.163 223.631 1.00 24.97  ? 66  ARG H CG  1 
ATOM   4762 C CD  . ARG C 3 67  ? 161.686 188.449 225.036 1.00 27.79  ? 66  ARG H CD  1 
ATOM   4763 N NE  . ARG C 3 67  ? 162.666 189.408 225.466 1.00 27.61  ? 66  ARG H NE  1 
ATOM   4764 C CZ  . ARG C 3 67  ? 162.384 190.661 225.897 1.00 26.90  ? 66  ARG H CZ  1 
ATOM   4765 N NH1 . ARG C 3 67  ? 161.148 191.121 225.942 1.00 26.67  ? 66  ARG H NH1 1 
ATOM   4766 N NH2 . ARG C 3 67  ? 163.371 191.435 226.299 1.00 26.62  ? 66  ARG H NH2 1 
ATOM   4767 N N   . PHE C 3 68  ? 161.668 190.971 220.027 1.00 22.35  ? 67  PHE H N   1 
ATOM   4768 C CA  . PHE C 3 68  ? 161.243 192.182 219.338 1.00 17.04  ? 67  PHE H CA  1 
ATOM   4769 C C   . PHE C 3 68  ? 161.411 192.077 217.830 1.00 15.30  ? 67  PHE H C   1 
ATOM   4770 O O   . PHE C 3 68  ? 162.362 191.480 217.339 1.00 15.83  ? 67  PHE H O   1 
ATOM   4771 C CB  . PHE C 3 68  ? 162.029 193.402 219.811 1.00 17.49  ? 67  PHE H CB  1 
ATOM   4772 C CG  . PHE C 3 68  ? 161.811 193.909 221.246 1.00 18.72  ? 67  PHE H CG  1 
ATOM   4773 C CD1 . PHE C 3 68  ? 161.093 193.228 222.216 1.00 21.27  ? 67  PHE H CD1 1 
ATOM   4774 C CD2 . PHE C 3 68  ? 162.359 195.110 221.611 1.00 18.04  ? 67  PHE H CD2 1 
ATOM   4775 C CE1 . PHE C 3 68  ? 160.952 193.727 223.471 1.00 21.56  ? 67  PHE H CE1 1 
ATOM   4776 C CE2 . PHE C 3 68  ? 162.207 195.607 222.876 1.00 18.44  ? 67  PHE H CE2 1 
ATOM   4777 C CZ  . PHE C 3 68  ? 161.510 194.913 223.800 1.00 20.59  ? 67  PHE H CZ  1 
ATOM   4778 N N   . THR C 3 69  ? 160.500 192.703 217.098 1.00 15.72  ? 68  THR H N   1 
ATOM   4779 C CA  . THR C 3 69  ? 160.611 192.834 215.646 1.00 13.77  ? 68  THR H CA  1 
ATOM   4780 C C   . THR C 3 69  ? 160.644 194.298 215.225 1.00 12.92  ? 68  THR H C   1 
ATOM   4781 O O   . THR C 3 69  ? 159.790 195.086 215.615 1.00 14.37  ? 68  THR H O   1 
ATOM   4782 C CB  . THR C 3 69  ? 159.470 192.112 214.907 1.00 16.63  ? 68  THR H CB  1 
ATOM   4783 O OG1 . THR C 3 69  ? 159.523 190.720 215.201 1.00 19.24  ? 68  THR H OG1 1 
ATOM   4784 C CG2 . THR C 3 69  ? 159.589 192.309 213.403 1.00 15.90  ? 68  THR H CG2 1 
ATOM   4785 N N   . ILE C 3 70  ? 161.616 194.675 214.401 1.00 12.26  ? 69  ILE H N   1 
ATOM   4786 C CA  . ILE C 3 70  ? 161.701 196.061 213.940 1.00 10.40  ? 69  ILE H CA  1 
ATOM   4787 C C   . ILE C 3 70  ? 161.285 196.055 212.496 1.00 9.78   ? 69  ILE H C   1 
ATOM   4788 O O   . ILE C 3 70  ? 161.724 195.207 211.723 1.00 10.88  ? 69  ILE H O   1 
ATOM   4789 C CB  . ILE C 3 70  ? 163.118 196.704 214.108 1.00 9.85   ? 69  ILE H CB  1 
ATOM   4790 C CG1 . ILE C 3 70  ? 163.058 198.217 213.714 1.00 8.37   ? 69  ILE H CG1 1 
ATOM   4791 C CG2 . ILE C 3 70  ? 164.169 195.999 213.306 1.00 7.91   ? 69  ILE H CG2 1 
ATOM   4792 C CD1 . ILE C 3 70  ? 164.292 199.042 214.072 1.00 7.21   ? 69  ILE H CD1 1 
ATOM   4793 N N   . SER C 3 71  ? 160.435 196.984 212.123 1.00 10.91  ? 70  SER H N   1 
ATOM   4794 C CA  . SER C 3 71  ? 160.001 197.017 210.749 1.00 9.47   ? 70  SER H CA  1 
ATOM   4795 C C   . SER C 3 71  ? 159.941 198.417 210.191 1.00 9.80   ? 70  SER H C   1 
ATOM   4796 O O   . SER C 3 71  ? 160.273 199.393 210.868 1.00 12.00  ? 70  SER H O   1 
ATOM   4797 C CB  . SER C 3 71  ? 158.664 196.353 210.616 1.00 11.34  ? 70  SER H CB  1 
ATOM   4798 O OG  . SER C 3 71  ? 158.341 196.196 209.270 1.00 0.00   ? 70  SER H OG  1 
ATOM   4799 N N   . ARG C 3 72  ? 159.563 198.500 208.930 1.00 10.83  ? 71  ARG H N   1 
ATOM   4800 C CA  . ARG C 3 72  ? 159.544 199.740 208.174 1.00 11.23  ? 71  ARG H CA  1 
ATOM   4801 C C   . ARG C 3 72  ? 158.560 199.754 207.026 1.00 13.58  ? 71  ARG H C   1 
ATOM   4802 O O   . ARG C 3 72  ? 158.447 198.783 206.280 1.00 15.56  ? 71  ARG H O   1 
ATOM   4803 C CB  . ARG C 3 72  ? 160.929 199.941 207.596 1.00 10.59  ? 71  ARG H CB  1 
ATOM   4804 C CG  . ARG C 3 72  ? 161.135 201.068 206.645 1.00 10.49  ? 71  ARG H CG  1 
ATOM   4805 C CD  . ARG C 3 72  ? 162.476 200.996 206.119 1.00 8.43   ? 71  ARG H CD  1 
ATOM   4806 N NE  . ARG C 3 72  ? 163.452 201.479 206.998 1.00 8.53   ? 71  ARG H NE  1 
ATOM   4807 C CZ  . ARG C 3 72  ? 163.922 202.729 206.991 1.00 7.82   ? 71  ARG H CZ  1 
ATOM   4808 N NH1 . ARG C 3 72  ? 163.502 203.622 206.127 1.00 9.01   ? 71  ARG H NH1 1 
ATOM   4809 N NH2 . ARG C 3 72  ? 164.846 203.050 207.818 1.00 8.09   ? 71  ARG H NH2 1 
ATOM   4810 N N   . ASP C 3 73  ? 157.942 200.903 206.813 1.00 15.78  ? 72  ASP H N   1 
ATOM   4811 C CA  . ASP C 3 73  ? 157.079 201.135 205.673 1.00 16.68  ? 72  ASP H CA  1 
ATOM   4812 C C   . ASP C 3 73  ? 157.486 202.430 204.990 1.00 16.18  ? 72  ASP H C   1 
ATOM   4813 O O   . ASP C 3 73  ? 157.272 203.536 205.499 1.00 19.77  ? 72  ASP H O   1 
ATOM   4814 C CB  . ASP C 3 73  ? 155.615 201.151 206.091 1.00 20.84  ? 72  ASP H CB  1 
ATOM   4815 C CG  . ASP C 3 73  ? 154.664 201.304 204.926 1.00 24.88  ? 72  ASP H CG  1 
ATOM   4816 O OD1 . ASP C 3 73  ? 155.013 201.967 203.948 1.00 27.34  ? 72  ASP H OD1 1 
ATOM   4817 O OD2 . ASP C 3 73  ? 153.575 200.746 204.989 1.00 27.52  ? 72  ASP H OD2 1 
ATOM   4818 N N   . ASN C 3 74  ? 158.115 202.310 203.825 1.00 18.43  ? 73  ASN H N   1 
ATOM   4819 C CA  . ASN C 3 74  ? 158.642 203.487 203.150 1.00 17.93  ? 73  ASN H CA  1 
ATOM   4820 C C   . ASN C 3 74  ? 157.603 204.262 202.363 1.00 20.13  ? 73  ASN H C   1 
ATOM   4821 O O   . ASN C 3 74  ? 157.908 205.323 201.821 1.00 20.97  ? 73  ASN H O   1 
ATOM   4822 C CB  . ASN C 3 74  ? 159.801 203.129 202.237 1.00 17.66  ? 73  ASN H CB  1 
ATOM   4823 C CG  . ASN C 3 74  ? 161.096 202.852 202.945 1.00 13.34  ? 73  ASN H CG  1 
ATOM   4824 O OD1 . ASN C 3 74  ? 161.337 203.372 204.030 1.00 13.07  ? 73  ASN H OD1 1 
ATOM   4825 N ND2 . ASN C 3 74  ? 161.937 202.072 202.335 1.00 11.46  ? 73  ASN H ND2 1 
ATOM   4826 N N   . SER C 3 75  ? 156.380 203.750 202.280 1.00 23.85  ? 74  SER H N   1 
ATOM   4827 C CA  . SER C 3 75  ? 155.336 204.456 201.556 1.00 23.89  ? 74  SER H CA  1 
ATOM   4828 C C   . SER C 3 75  ? 154.597 205.363 202.518 1.00 23.81  ? 74  SER H C   1 
ATOM   4829 O O   . SER C 3 75  ? 154.121 206.437 202.152 1.00 26.19  ? 74  SER H O   1 
ATOM   4830 C CB  . SER C 3 75  ? 154.364 203.482 200.930 1.00 26.72  ? 74  SER H CB  1 
ATOM   4831 O OG  . SER C 3 75  ? 154.985 202.697 199.950 1.00 30.23  ? 74  SER H OG  1 
ATOM   4832 N N   . LYS C 3 76  ? 154.543 204.936 203.775 1.00 22.46  ? 75  LYS H N   1 
ATOM   4833 C CA  . LYS C 3 76  ? 153.846 205.675 204.819 1.00 22.36  ? 75  LYS H CA  1 
ATOM   4834 C C   . LYS C 3 76  ? 154.771 206.390 205.800 1.00 24.15  ? 75  LYS H C   1 
ATOM   4835 O O   . LYS C 3 76  ? 154.329 206.826 206.864 1.00 26.34  ? 75  LYS H O   1 
ATOM   4836 C CB  . LYS C 3 76  ? 152.905 204.764 205.593 1.00 25.29  ? 75  LYS H CB  1 
ATOM   4837 C CG  . LYS C 3 76  ? 151.777 204.189 204.746 1.00 29.83  ? 75  LYS H CG  1 
ATOM   4838 C CD  . LYS C 3 76  ? 150.651 203.569 205.610 1.00 35.49  ? 75  LYS H CD  1 
ATOM   4839 C CE  . LYS C 3 76  ? 151.034 202.249 206.288 1.00 37.35  ? 75  LYS H CE  1 
ATOM   4840 N NZ  . LYS C 3 76  ? 151.186 201.136 205.321 1.00 38.19  ? 75  LYS H NZ  1 
ATOM   4841 N N   . ASN C 3 77  ? 156.063 206.419 205.513 1.00 20.50  ? 76  ASN H N   1 
ATOM   4842 C CA  . ASN C 3 77  ? 157.054 207.057 206.369 1.00 16.01  ? 76  ASN H CA  1 
ATOM   4843 C C   . ASN C 3 77  ? 156.929 206.611 207.806 1.00 15.52  ? 76  ASN H C   1 
ATOM   4844 O O   . ASN C 3 77  ? 156.953 207.418 208.741 1.00 18.05  ? 76  ASN H O   1 
ATOM   4845 C CB  . ASN C 3 77  ? 157.026 208.553 206.249 1.00 17.46  ? 76  ASN H CB  1 
ATOM   4846 C CG  . ASN C 3 77  ? 157.423 208.999 204.901 1.00 17.58  ? 76  ASN H CG  1 
ATOM   4847 O OD1 . ASN C 3 77  ? 157.952 208.226 204.098 1.00 18.67  ? 76  ASN H OD1 1 
ATOM   4848 N ND2 . ASN C 3 77  ? 157.219 210.247 204.631 1.00 19.43  ? 76  ASN H ND2 1 
ATOM   4849 N N   . THR C 3 78  ? 156.767 205.313 207.990 1.00 17.07  ? 77  THR H N   1 
ATOM   4850 C CA  . THR C 3 78  ? 156.580 204.787 209.322 1.00 15.61  ? 77  THR H CA  1 
ATOM   4851 C C   . THR C 3 78  ? 157.578 203.724 209.761 1.00 14.94  ? 77  THR H C   1 
ATOM   4852 O O   . THR C 3 78  ? 157.863 202.740 209.073 1.00 16.16  ? 77  THR H O   1 
ATOM   4853 C CB  . THR C 3 78  ? 155.138 204.262 209.463 1.00 18.44  ? 77  THR H CB  1 
ATOM   4854 O OG1 . THR C 3 78  ? 154.218 205.355 209.257 1.00 20.65  ? 77  THR H OG1 1 
ATOM   4855 C CG2 . THR C 3 78  ? 154.901 203.673 210.859 1.00 18.20  ? 77  THR H CG2 1 
ATOM   4856 N N   . LEU C 3 79  ? 158.111 203.936 210.950 1.00 14.83  ? 78  LEU H N   1 
ATOM   4857 C CA  . LEU C 3 79  ? 159.019 203.004 211.607 1.00 13.29  ? 78  LEU H CA  1 
ATOM   4858 C C   . LEU C 3 79  ? 158.216 202.310 212.688 1.00 13.31  ? 78  LEU H C   1 
ATOM   4859 O O   . LEU C 3 79  ? 157.400 202.955 213.348 1.00 16.36  ? 78  LEU H O   1 
ATOM   4860 C CB  . LEU C 3 79  ? 160.212 203.737 212.249 1.00 13.21  ? 78  LEU H CB  1 
ATOM   4861 C CG  . LEU C 3 79  ? 161.302 202.865 212.966 1.00 10.82  ? 78  LEU H CG  1 
ATOM   4862 C CD1 . LEU C 3 79  ? 162.094 202.110 211.937 1.00 10.20  ? 78  LEU H CD1 1 
ATOM   4863 C CD2 . LEU C 3 79  ? 162.184 203.738 213.832 1.00 10.02  ? 78  LEU H CD2 1 
ATOM   4864 N N   . SER C 3 80  ? 158.424 201.021 212.911 1.00 13.24  ? 79  SER H N   1 
ATOM   4865 C CA  . SER C 3 80  ? 157.678 200.389 213.994 1.00 12.41  ? 79  SER H CA  1 
ATOM   4866 C C   . SER C 3 80  ? 158.450 199.326 214.741 1.00 11.16  ? 79  SER H C   1 
ATOM   4867 O O   . SER C 3 80  ? 159.435 198.775 214.243 1.00 13.62  ? 79  SER H O   1 
ATOM   4868 C CB  . SER C 3 80  ? 156.415 199.795 213.438 1.00 15.72  ? 79  SER H CB  1 
ATOM   4869 O OG  . SER C 3 80  ? 156.714 198.769 212.545 1.00 17.36  ? 79  SER H OG  1 
ATOM   4870 N N   . LEU C 3 81  ? 158.001 199.049 215.962 1.00 12.99  ? 80  LEU H N   1 
ATOM   4871 C CA  . LEU C 3 81  ? 158.611 198.017 216.787 1.00 13.51  ? 80  LEU H CA  1 
ATOM   4872 C C   . LEU C 3 81  ? 157.540 197.179 217.471 1.00 16.36  ? 80  LEU H C   1 
ATOM   4873 O O   . LEU C 3 81  ? 156.724 197.684 218.242 1.00 18.95  ? 80  LEU H O   1 
ATOM   4874 C CB  . LEU C 3 81  ? 159.491 198.669 217.879 1.00 11.57  ? 80  LEU H CB  1 
ATOM   4875 C CG  . LEU C 3 81  ? 160.275 197.760 218.869 1.00 11.47  ? 80  LEU H CG  1 
ATOM   4876 C CD1 . LEU C 3 81  ? 161.349 196.996 218.125 1.00 11.52  ? 80  LEU H CD1 1 
ATOM   4877 C CD2 . LEU C 3 81  ? 160.884 198.610 219.967 1.00 10.61  ? 80  LEU H CD2 1 
ATOM   4878 N N   . GLN C 3 82  ? 157.560 195.884 217.240 1.00 17.01  ? 81  GLN H N   1 
ATOM   4879 C CA  . GLN C 3 82  ? 156.595 195.011 217.881 1.00 18.59  ? 81  GLN H CA  1 
ATOM   4880 C C   . GLN C 3 82  ? 157.272 194.271 218.995 1.00 19.07  ? 81  GLN H C   1 
ATOM   4881 O O   . GLN C 3 82  ? 158.179 193.474 218.758 1.00 20.99  ? 81  GLN H O   1 
ATOM   4882 C CB  . GLN C 3 82  ? 155.980 194.012 216.907 1.00 21.02  ? 81  GLN H CB  1 
ATOM   4883 C CG  . GLN C 3 82  ? 155.018 193.010 217.562 1.00 24.62  ? 81  GLN H CG  1 
ATOM   4884 C CD  . GLN C 3 82  ? 153.697 193.598 218.033 1.00 24.77  ? 81  GLN H CD  1 
ATOM   4885 O OE1 . GLN C 3 82  ? 152.899 194.039 217.207 1.00 25.85  ? 81  GLN H OE1 1 
ATOM   4886 N NE2 . GLN C 3 82  ? 153.453 193.599 219.344 1.00 27.12  ? 81  GLN H NE2 1 
ATOM   4887 N N   . MET C 3 83  ? 156.855 194.525 220.220 1.00 22.21  ? 82  MET H N   1 
ATOM   4888 C CA  . MET C 3 83  ? 157.508 193.890 221.336 1.00 21.00  ? 82  MET H CA  1 
ATOM   4889 C C   . MET C 3 83  ? 156.659 192.790 221.932 1.00 24.25  ? 82  MET H C   1 
ATOM   4890 O O   . MET C 3 83  ? 155.489 193.017 222.253 1.00 28.38  ? 82  MET H O   1 
ATOM   4891 C CB  . MET C 3 83  ? 157.749 194.934 222.389 1.00 23.28  ? 82  MET H CB  1 
ATOM   4892 C CG  . MET C 3 83  ? 158.569 196.088 221.912 1.00 19.19  ? 82  MET H CG  1 
ATOM   4893 S SD  . MET C 3 83  ? 158.886 197.312 223.153 1.00 18.40  ? 82  MET H SD  1 
ATOM   4894 C CE  . MET C 3 83  ? 157.354 198.094 223.224 1.00 19.39  ? 82  MET H CE  1 
ATOM   4895 N N   . HIS C 3 84  A 157.266 191.631 222.197 1.00 26.14  ? 82  HIS H N   1 
ATOM   4896 C CA  . HIS C 3 84  A 156.552 190.538 222.840 1.00 27.68  ? 82  HIS H CA  1 
ATOM   4897 C C   . HIS C 3 84  A 157.234 190.065 224.119 1.00 28.08  ? 82  HIS H C   1 
ATOM   4898 O O   . HIS C 3 84  A 158.446 190.222 224.308 1.00 32.57  ? 82  HIS H O   1 
ATOM   4899 C CB  . HIS C 3 84  A 156.431 189.335 221.905 1.00 27.73  ? 82  HIS H CB  1 
ATOM   4900 C CG  . HIS C 3 84  A 155.623 189.561 220.674 1.00 28.44  ? 82  HIS H CG  1 
ATOM   4901 N ND1 . HIS C 3 84  A 154.251 189.639 220.689 1.00 30.03  ? 82  HIS H ND1 1 
ATOM   4902 C CD2 . HIS C 3 84  A 155.988 189.681 219.387 1.00 27.49  ? 82  HIS H CD2 1 
ATOM   4903 C CE1 . HIS C 3 84  A 153.811 189.808 219.463 1.00 29.40  ? 82  HIS H CE1 1 
ATOM   4904 N NE2 . HIS C 3 84  A 154.840 189.825 218.654 1.00 28.20  ? 82  HIS H NE2 1 
ATOM   4905 N N   . SER C 3 85  B 156.420 189.526 225.020 1.00 29.46  ? 82  SER H N   1 
ATOM   4906 C CA  . SER C 3 85  B 156.767 188.895 226.295 1.00 30.35  ? 82  SER H CA  1 
ATOM   4907 C C   . SER C 3 85  B 157.193 189.888 227.370 1.00 32.46  ? 82  SER H C   1 
ATOM   4908 O O   . SER C 3 85  B 157.381 189.512 228.527 1.00 31.63  ? 82  SER H O   1 
ATOM   4909 C CB  . SER C 3 85  B 157.830 187.838 226.108 1.00 29.38  ? 82  SER H CB  1 
ATOM   4910 O OG  . SER C 3 85  B 157.418 186.853 225.199 1.00 30.57  ? 82  SER H OG  1 
ATOM   4911 N N   . LEU C 3 86  C 157.284 191.148 226.987 1.00 29.22  ? 82  LEU H N   1 
ATOM   4912 C CA  . LEU C 3 86  C 157.481 192.301 227.836 1.00 29.69  ? 82  LEU H CA  1 
ATOM   4913 C C   . LEU C 3 86  C 157.778 192.032 229.285 1.00 31.56  ? 82  LEU H C   1 
ATOM   4914 O O   . LEU C 3 86  C 156.888 191.751 230.090 1.00 37.51  ? 82  LEU H O   1 
ATOM   4915 C CB  . LEU C 3 86  C 156.326 193.250 227.629 1.00 30.10  ? 82  LEU H CB  1 
ATOM   4916 C CG  . LEU C 3 86  C 156.320 193.907 226.216 1.00 29.72  ? 82  LEU H CG  1 
ATOM   4917 C CD1 . LEU C 3 86  C 155.108 194.606 226.032 1.00 30.77  ? 82  LEU H CD1 1 
ATOM   4918 C CD2 . LEU C 3 86  C 157.468 194.943 226.094 1.00 26.68  ? 82  LEU H CD2 1 
ATOM   4919 N N   . ARG C 3 87  ? 159.054 192.043 229.585 1.00 31.62  ? 83  ARG H N   1 
ATOM   4920 C CA  . ARG C 3 87  ? 159.583 191.800 230.904 1.00 33.49  ? 83  ARG H CA  1 
ATOM   4921 C C   . ARG C 3 87  ? 159.498 193.092 231.698 1.00 34.75  ? 83  ARG H C   1 
ATOM   4922 O O   . ARG C 3 87  ? 159.395 194.175 231.138 1.00 36.88  ? 83  ARG H O   1 
ATOM   4923 C CB  . ARG C 3 87  ? 161.021 191.332 230.792 1.00 34.60  ? 83  ARG H CB  1 
ATOM   4924 C CG  . ARG C 3 87  ? 161.178 189.997 230.087 1.00 33.68  ? 83  ARG H CG  1 
ATOM   4925 C CD  . ARG C 3 87  ? 162.591 189.645 229.877 1.00 35.56  ? 83  ARG H CD  1 
ATOM   4926 N NE  . ARG C 3 87  ? 162.723 188.385 229.164 1.00 36.92  ? 83  ARG H NE  1 
ATOM   4927 C CZ  . ARG C 3 87  ? 163.878 187.889 228.668 1.00 37.30  ? 83  ARG H CZ  1 
ATOM   4928 N NH1 . ARG C 3 87  ? 165.005 188.559 228.800 1.00 38.23  ? 83  ARG H NH1 1 
ATOM   4929 N NH2 . ARG C 3 87  ? 163.876 186.720 228.046 1.00 40.85  ? 83  ARG H NH2 1 
ATOM   4930 N N   . ASP C 3 88  ? 159.582 193.035 233.013 1.00 39.77  ? 84  ASP H N   1 
ATOM   4931 C CA  . ASP C 3 88  ? 159.538 194.267 233.800 1.00 41.10  ? 84  ASP H CA  1 
ATOM   4932 C C   . ASP C 3 88  ? 160.733 195.152 233.463 1.00 38.51  ? 84  ASP H C   1 
ATOM   4933 O O   . ASP C 3 88  ? 160.647 196.387 233.407 1.00 37.30  ? 84  ASP H O   1 
ATOM   4934 C CB  . ASP C 3 88  ? 159.565 193.881 235.263 1.00 45.81  ? 84  ASP H CB  1 
ATOM   4935 C CG  . ASP C 3 88  ? 160.784 193.004 235.532 1.00 46.30  ? 84  ASP H CG  1 
ATOM   4936 O OD1 . ASP C 3 88  ? 161.206 192.318 234.585 1.00 44.30  ? 84  ASP H OD1 1 
ATOM   4937 O OD2 . ASP C 3 88  ? 161.282 193.001 236.621 1.00 50.58  ? 84  ASP H OD2 1 
ATOM   4938 N N   . GLY C 3 89  ? 161.807 194.493 233.076 1.00 38.84  ? 85  GLY H N   1 
ATOM   4939 C CA  . GLY C 3 89  ? 163.066 195.099 232.681 1.00 38.37  ? 85  GLY H CA  1 
ATOM   4940 C C   . GLY C 3 89  ? 162.973 195.875 231.363 1.00 32.34  ? 85  GLY H C   1 
ATOM   4941 O O   . GLY C 3 89  ? 163.916 196.567 230.988 1.00 31.29  ? 85  GLY H O   1 
ATOM   4942 N N   . ASP C 3 90  ? 161.847 195.773 230.655 1.00 33.21  ? 86  ASP H N   1 
ATOM   4943 C CA  . ASP C 3 90  ? 161.663 196.486 229.407 1.00 27.60  ? 86  ASP H CA  1 
ATOM   4944 C C   . ASP C 3 90  ? 160.990 197.844 229.625 1.00 26.32  ? 86  ASP H C   1 
ATOM   4945 O O   . ASP C 3 90  ? 160.725 198.559 228.650 1.00 25.82  ? 86  ASP H O   1 
ATOM   4946 C CB  . ASP C 3 90  ? 160.826 195.663 228.410 1.00 28.01  ? 86  ASP H CB  1 
ATOM   4947 C CG  . ASP C 3 90  ? 161.499 194.370 227.785 1.00 27.89  ? 86  ASP H CG  1 
ATOM   4948 O OD1 . ASP C 3 90  ? 162.649 194.370 227.359 1.00 26.83  ? 86  ASP H OD1 1 
ATOM   4949 O OD2 . ASP C 3 90  ? 160.818 193.359 227.747 1.00 30.73  ? 86  ASP H OD2 1 
ATOM   4950 N N   . THR C 3 91  ? 160.719 198.231 230.886 1.00 28.73  ? 87  THR H N   1 
ATOM   4951 C CA  . THR C 3 91  ? 160.126 199.554 231.108 1.00 27.19  ? 87  THR H CA  1 
ATOM   4952 C C   . THR C 3 91  ? 161.157 200.601 230.765 1.00 26.54  ? 87  THR H C   1 
ATOM   4953 O O   . THR C 3 91  ? 162.280 200.572 231.270 1.00 29.37  ? 87  THR H O   1 
ATOM   4954 C CB  . THR C 3 91  ? 159.666 199.761 232.567 1.00 29.58  ? 87  THR H CB  1 
ATOM   4955 O OG1 . THR C 3 91  ? 158.634 198.814 232.888 1.00 32.50  ? 87  THR H OG1 1 
ATOM   4956 C CG2 . THR C 3 91  ? 159.181 201.213 232.803 1.00 30.92  ? 87  THR H CG2 1 
ATOM   4957 N N   . ALA C 3 92  ? 160.774 201.514 229.888 1.00 24.18  ? 88  ALA H N   1 
ATOM   4958 C CA  . ALA C 3 92  ? 161.685 202.539 229.418 1.00 19.94  ? 88  ALA H CA  1 
ATOM   4959 C C   . ALA C 3 92  ? 161.030 203.526 228.501 1.00 18.82  ? 88  ALA H C   1 
ATOM   4960 O O   . ALA C 3 92  ? 159.946 203.269 227.982 1.00 22.62  ? 88  ALA H O   1 
ATOM   4961 C CB  . ALA C 3 92  ? 162.811 201.906 228.687 1.00 20.38  ? 88  ALA H CB  1 
ATOM   4962 N N   . VAL C 3 93  ? 161.719 204.619 228.238 1.00 19.46  ? 89  VAL H N   1 
ATOM   4963 C CA  . VAL C 3 93  ? 161.309 205.482 227.154 1.00 17.09  ? 89  VAL H CA  1 
ATOM   4964 C C   . VAL C 3 93  ? 161.971 204.979 225.880 1.00 16.02  ? 89  VAL H C   1 
ATOM   4965 O O   . VAL C 3 93  ? 163.173 204.732 225.848 1.00 17.35  ? 89  VAL H O   1 
ATOM   4966 C CB  . VAL C 3 93  ? 161.680 206.936 227.413 1.00 16.12  ? 89  VAL H CB  1 
ATOM   4967 C CG1 . VAL C 3 93  ? 161.318 207.777 226.221 1.00 16.06  ? 89  VAL H CG1 1 
ATOM   4968 C CG2 . VAL C 3 93  ? 160.943 207.403 228.604 1.00 17.60  ? 89  VAL H CG2 1 
ATOM   4969 N N   . TYR C 3 94  ? 161.187 204.777 224.844 1.00 16.39  ? 90  TYR H N   1 
ATOM   4970 C CA  . TYR C 3 94  ? 161.700 204.284 223.583 1.00 13.39  ? 90  TYR H CA  1 
ATOM   4971 C C   . TYR C 3 94  ? 161.751 205.378 222.563 1.00 13.78  ? 90  TYR H C   1 
ATOM   4972 O O   . TYR C 3 94  ? 160.719 205.906 222.140 1.00 16.95  ? 90  TYR H O   1 
ATOM   4973 C CB  . TYR C 3 94  ? 160.847 203.125 223.093 1.00 14.97  ? 90  TYR H CB  1 
ATOM   4974 C CG  . TYR C 3 94  ? 161.022 201.851 223.871 1.00 14.10  ? 90  TYR H CG  1 
ATOM   4975 C CD1 . TYR C 3 94  ? 160.468 201.700 225.103 1.00 16.35  ? 90  TYR H CD1 1 
ATOM   4976 C CD2 . TYR C 3 94  ? 161.720 200.818 223.313 1.00 13.59  ? 90  TYR H CD2 1 
ATOM   4977 C CE1 . TYR C 3 94  ? 160.634 200.539 225.789 1.00 16.67  ? 90  TYR H CE1 1 
ATOM   4978 C CE2 . TYR C 3 94  ? 161.867 199.654 223.998 1.00 14.90  ? 90  TYR H CE2 1 
ATOM   4979 C CZ  . TYR C 3 94  ? 161.325 199.524 225.245 1.00 16.19  ? 90  TYR H CZ  1 
ATOM   4980 O OH  . TYR C 3 94  ? 161.481 198.358 225.965 1.00 19.13  ? 90  TYR H OH  1 
ATOM   4981 N N   . TYR C 3 95  ? 162.960 205.717 222.149 1.00 14.45  ? 91  TYR H N   1 
ATOM   4982 C CA  . TYR C 3 95  ? 163.160 206.803 221.221 1.00 13.97  ? 91  TYR H CA  1 
ATOM   4983 C C   . TYR C 3 95  ? 163.358 206.286 219.806 1.00 12.86  ? 91  TYR H C   1 
ATOM   4984 O O   . TYR C 3 95  ? 164.142 205.361 219.574 1.00 12.04  ? 91  TYR H O   1 
ATOM   4985 C CB  . TYR C 3 95  ? 164.422 207.594 221.566 1.00 13.15  ? 91  TYR H CB  1 
ATOM   4986 C CG  . TYR C 3 95  ? 164.432 208.292 222.865 1.00 12.84  ? 91  TYR H CG  1 
ATOM   4987 C CD1 . TYR C 3 95  ? 163.857 209.519 223.012 1.00 14.44  ? 91  TYR H CD1 1 
ATOM   4988 C CD2 . TYR C 3 95  ? 165.044 207.687 223.927 1.00 12.82  ? 91  TYR H CD2 1 
ATOM   4989 C CE1 . TYR C 3 95  ? 163.900 210.131 224.232 1.00 14.52  ? 91  TYR H CE1 1 
ATOM   4990 C CE2 . TYR C 3 95  ? 165.087 208.298 225.121 1.00 13.41  ? 91  TYR H CE2 1 
ATOM   4991 C CZ  . TYR C 3 95  ? 164.516 209.521 225.278 1.00 13.80  ? 91  TYR H CZ  1 
ATOM   4992 O OH  . TYR C 3 95  ? 164.573 210.132 226.501 1.00 17.35  ? 91  TYR H OH  1 
ATOM   4993 N N   . CYS C 3 96  ? 162.721 206.968 218.853 1.00 14.41  ? 92  CYS H N   1 
ATOM   4994 C CA  . CYS C 3 96  ? 162.818 206.781 217.421 1.00 12.79  ? 92  CYS H CA  1 
ATOM   4995 C C   . CYS C 3 96  ? 164.026 207.605 216.991 1.00 15.40  ? 92  CYS H C   1 
ATOM   4996 O O   . CYS C 3 96  ? 164.125 208.804 217.282 1.00 17.01  ? 92  CYS H O   1 
ATOM   4997 C CB  . CYS C 3 96  ? 161.498 207.284 216.780 1.00 15.66  ? 92  CYS H CB  1 
ATOM   4998 S SG  . CYS C 3 96  ? 161.308 207.215 215.045 1.00 25.07  ? 92  CYS H SG  1 
ATOM   4999 N N   . ALA C 3 97  ? 164.984 206.990 216.324 1.00 15.20  ? 93  ALA H N   1 
ATOM   5000 C CA  . ALA C 3 97  ? 166.145 207.763 215.923 1.00 10.84  ? 93  ALA H CA  1 
ATOM   5001 C C   . ALA C 3 97  ? 166.568 207.423 214.518 1.00 9.29   ? 93  ALA H C   1 
ATOM   5002 O O   . ALA C 3 97  ? 166.407 206.303 214.044 1.00 10.57  ? 93  ALA H O   1 
ATOM   5003 C CB  . ALA C 3 97  ? 167.296 207.538 216.894 1.00 9.29   ? 93  ALA H CB  1 
ATOM   5004 N N   . THR C 3 98  ? 167.123 208.409 213.850 1.00 10.86  ? 94  THR H N   1 
ATOM   5005 C CA  . THR C 3 98  ? 167.601 208.254 212.492 1.00 8.95   ? 94  THR H CA  1 
ATOM   5006 C C   . THR C 3 98  ? 169.094 208.140 212.508 1.00 7.65   ? 94  THR H C   1 
ATOM   5007 O O   . THR C 3 98  ? 169.765 209.000 213.086 1.00 11.48  ? 94  THR H O   1 
ATOM   5008 C CB  . THR C 3 98  ? 167.191 209.463 211.651 1.00 10.25  ? 94  THR H CB  1 
ATOM   5009 O OG1 . THR C 3 98  ? 165.793 209.571 211.643 1.00 12.84  ? 94  THR H OG1 1 
ATOM   5010 C CG2 . THR C 3 98  ? 167.626 209.320 210.268 1.00 11.93  ? 94  THR H CG2 1 
ATOM   5011 N N   . GLY C 3 99  ? 169.608 207.083 211.888 1.00 7.32   ? 95  GLY H N   1 
ATOM   5012 C CA  . GLY C 3 99  ? 171.031 206.823 211.840 1.00 5.22   ? 95  GLY H CA  1 
ATOM   5013 C C   . GLY C 3 99  ? 171.369 205.399 212.243 1.00 4.26   ? 95  GLY H C   1 
ATOM   5014 O O   . GLY C 3 99  ? 170.522 204.518 212.247 1.00 6.13   ? 95  GLY H O   1 
ATOM   5015 N N   . GLY C 3 100 ? 172.644 205.175 212.501 1.00 4.04   ? 96  GLY H N   1 
ATOM   5016 C CA  . GLY C 3 100 ? 173.194 203.878 212.865 1.00 3.64   ? 96  GLY H CA  1 
ATOM   5017 C C   . GLY C 3 100 ? 173.752 203.029 211.719 1.00 3.09   ? 96  GLY H C   1 
ATOM   5018 O O   . GLY C 3 100 ? 174.458 202.059 211.978 1.00 4.19   ? 96  GLY H O   1 
ATOM   5019 N N   . MET C 3 101 ? 173.466 203.382 210.471 1.00 3.67   ? 97  MET H N   1 
ATOM   5020 C CA  . MET C 3 101 ? 173.945 202.599 209.328 1.00 2.52   ? 97  MET H CA  1 
ATOM   5021 C C   . MET C 3 101 ? 173.772 203.334 207.996 1.00 3.02   ? 97  MET H C   1 
ATOM   5022 O O   . MET C 3 101 ? 172.987 204.279 207.908 1.00 4.14   ? 97  MET H O   1 
ATOM   5023 C CB  . MET C 3 101 ? 173.237 201.252 209.341 1.00 3.27   ? 97  MET H CB  1 
ATOM   5024 C CG  . MET C 3 101 ? 173.580 200.278 208.261 1.00 5.39   ? 97  MET H CG  1 
ATOM   5025 S SD  . MET C 3 101 ? 172.924 198.649 208.582 1.00 7.18   ? 97  MET H SD  1 
ATOM   5026 C CE  . MET C 3 101 ? 171.227 198.917 208.389 1.00 3.97   ? 97  MET H CE  1 
ATOM   5027 N N   . SER C 3 102 ? 174.548 202.920 206.989 1.00 2.84   ? 98  SER H N   1 
ATOM   5028 C CA  . SER C 3 102 ? 174.490 203.421 205.610 1.00 2.28   ? 98  SER H CA  1 
ATOM   5029 C C   . SER C 3 102 ? 174.462 202.265 204.625 1.00 2.80   ? 98  SER H C   1 
ATOM   5030 O O   . SER C 3 102 ? 174.593 201.113 205.027 1.00 3.92   ? 98  SER H O   1 
ATOM   5031 C CB  . SER C 3 102 ? 175.649 204.308 205.290 1.00 3.04   ? 98  SER H CB  1 
ATOM   5032 O OG  . SER C 3 102 ? 175.651 205.422 206.088 1.00 4.83   ? 98  SER H OG  1 
ATOM   5033 N N   . SER C 3 103 ? 174.322 202.568 203.332 1.00 2.61   ? 99  SER H N   1 
ATOM   5034 C CA  . SER C 3 103 ? 174.211 201.546 202.284 1.00 0.35   ? 99  SER H CA  1 
ATOM   5035 C C   . SER C 3 103 ? 175.394 201.258 201.358 1.00 1.36   ? 99  SER H C   1 
ATOM   5036 O O   . SER C 3 103 ? 175.168 200.981 200.185 1.00 3.95   ? 99  SER H O   1 
ATOM   5037 C CB  . SER C 3 103 ? 173.083 201.881 201.359 1.00 2.23   ? 99  SER H CB  1 
ATOM   5038 O OG  . SER C 3 103 ? 173.322 203.080 200.733 1.00 4.60   ? 99  SER H OG  1 
ATOM   5039 N N   . ALA C 3 104 ? 176.648 201.393 201.781 1.00 1.47   ? 100 ALA H N   1 
ATOM   5040 C CA  . ALA C 3 104 ? 177.847 201.090 200.953 1.00 0.65   ? 100 ALA H CA  1 
ATOM   5041 C C   . ALA C 3 104 ? 178.146 202.104 199.835 1.00 1.04   ? 100 ALA H C   1 
ATOM   5042 O O   . ALA C 3 104 ? 179.308 202.367 199.520 1.00 1.46   ? 100 ALA H O   1 
ATOM   5043 C CB  . ALA C 3 104 ? 177.765 199.693 200.340 1.00 0.54   ? 100 ALA H CB  1 
ATOM   5044 N N   . LEU C 3 105 A 177.127 202.674 199.217 1.00 1.75   ? 100 LEU H N   1 
ATOM   5045 C CA  . LEU C 3 105 A 177.319 203.662 198.164 1.00 1.29   ? 100 LEU H CA  1 
ATOM   5046 C C   . LEU C 3 105 A 177.162 205.062 198.736 1.00 1.46   ? 100 LEU H C   1 
ATOM   5047 O O   . LEU C 3 105 A 177.157 206.053 198.017 1.00 2.89   ? 100 LEU H O   1 
ATOM   5048 C CB  . LEU C 3 105 A 176.303 203.470 197.060 1.00 1.59   ? 100 LEU H CB  1 
ATOM   5049 C CG  . LEU C 3 105 A 176.246 202.095 196.429 1.00 0.75   ? 100 LEU H CG  1 
ATOM   5050 C CD1 . LEU C 3 105 A 175.243 202.138 195.321 1.00 1.47   ? 100 LEU H CD1 1 
ATOM   5051 C CD2 . LEU C 3 105 A 177.575 201.647 195.958 1.00 2.21   ? 100 LEU H CD2 1 
ATOM   5052 N N   . GLN C 3 106 B 177.000 205.120 200.041 1.00 1.48   ? 100 GLN H N   1 
ATOM   5053 C CA  . GLN C 3 106 B 176.811 206.323 200.826 1.00 1.73   ? 100 GLN H CA  1 
ATOM   5054 C C   . GLN C 3 106 B 177.929 206.490 201.825 1.00 2.28   ? 100 GLN H C   1 
ATOM   5055 O O   . GLN C 3 106 B 178.570 205.519 202.205 1.00 2.43   ? 100 GLN H O   1 
ATOM   5056 C CB  . GLN C 3 106 B 175.509 206.262 201.619 1.00 1.59   ? 100 GLN H CB  1 
ATOM   5057 C CG  . GLN C 3 106 B 174.225 206.279 200.851 1.00 0.81   ? 100 GLN H CG  1 
ATOM   5058 C CD  . GLN C 3 106 B 173.046 206.115 201.802 1.00 0.12   ? 100 GLN H CD  1 
ATOM   5059 O OE1 . GLN C 3 106 B 173.057 205.155 202.594 1.00 4.65   ? 100 GLN H OE1 1 
ATOM   5060 N NE2 . GLN C 3 106 B 172.047 207.005 201.738 1.00 0.01   ? 100 GLN H NE2 1 
ATOM   5061 N N   . SER C 3 107 C 178.149 207.712 202.280 1.00 3.08   ? 100 SER H N   1 
ATOM   5062 C CA  . SER C 3 107 C 179.089 207.940 203.359 1.00 3.88   ? 100 SER H CA  1 
ATOM   5063 C C   . SER C 3 107 C 178.518 207.239 204.560 1.00 5.72   ? 100 SER H C   1 
ATOM   5064 O O   . SER C 3 107 C 177.296 207.134 204.674 1.00 7.60   ? 100 SER H O   1 
ATOM   5065 C CB  . SER C 3 107 C 179.245 209.409 203.652 1.00 5.97   ? 100 SER H CB  1 
ATOM   5066 O OG  . SER C 3 107 C 179.780 210.084 202.558 1.00 16.88  ? 100 SER H OG  1 
ATOM   5067 N N   . SER C 3 108 D 179.370 206.769 205.447 1.00 6.99   ? 100 SER H N   1 
ATOM   5068 C CA  . SER C 3 108 D 178.940 206.054 206.625 1.00 4.58   ? 100 SER H CA  1 
ATOM   5069 C C   . SER C 3 108 D 178.291 206.913 207.675 1.00 5.68   ? 100 SER H C   1 
ATOM   5070 O O   . SER C 3 108 D 178.423 208.135 207.667 1.00 23.10  ? 100 SER H O   1 
ATOM   5071 C CB  . SER C 3 108 D 180.119 205.348 207.222 1.00 4.64   ? 100 SER H CB  1 
ATOM   5072 O OG  . SER C 3 108 D 181.073 206.244 207.692 1.00 7.41   ? 100 SER H OG  1 
ATOM   5073 N N   . LYS C 3 109 E 177.577 206.251 208.580 1.00 5.25   ? 100 LYS H N   1 
ATOM   5074 C CA  . LYS C 3 109 E 176.967 206.900 209.718 1.00 3.78   ? 100 LYS H CA  1 
ATOM   5075 C C   . LYS C 3 109 E 177.648 206.477 210.982 1.00 5.39   ? 100 LYS H C   1 
ATOM   5076 O O   . LYS C 3 109 E 178.671 207.031 211.334 1.00 7.09   ? 100 LYS H O   1 
ATOM   5077 C CB  . LYS C 3 109 E 175.477 206.618 209.832 1.00 2.97   ? 100 LYS H CB  1 
ATOM   5078 C CG  . LYS C 3 109 E 174.625 207.222 208.797 1.00 3.54   ? 100 LYS H CG  1 
ATOM   5079 C CD  . LYS C 3 109 E 174.534 208.710 208.944 1.00 3.89   ? 100 LYS H CD  1 
ATOM   5080 C CE  . LYS C 3 109 E 173.619 209.287 207.932 1.00 8.45   ? 100 LYS H CE  1 
ATOM   5081 N NZ  . LYS C 3 109 E 173.601 210.741 208.007 1.00 7.79   ? 100 LYS H NZ  1 
ATOM   5082 N N   . TYR C 3 110 F 177.118 205.462 211.617 1.00 3.04   ? 100 TYR H N   1 
ATOM   5083 C CA  . TYR C 3 110 F 177.579 204.954 212.895 1.00 3.14   ? 100 TYR H CA  1 
ATOM   5084 C C   . TYR C 3 110 F 177.377 205.909 214.056 1.00 4.00   ? 100 TYR H C   1 
ATOM   5085 O O   . TYR C 3 110 F 178.065 205.814 215.070 1.00 0.00   ? 100 TYR H O   1 
ATOM   5086 C CB  . TYR C 3 110 F 179.029 204.523 212.857 1.00 3.67   ? 100 TYR H CB  1 
ATOM   5087 C CG  . TYR C 3 110 F 179.336 203.502 211.853 1.00 3.36   ? 100 TYR H CG  1 
ATOM   5088 C CD1 . TYR C 3 110 F 178.827 202.268 211.973 1.00 3.76   ? 100 TYR H CD1 1 
ATOM   5089 C CD2 . TYR C 3 110 F 180.132 203.797 210.819 1.00 4.11   ? 100 TYR H CD2 1 
ATOM   5090 C CE1 . TYR C 3 110 F 179.130 201.319 211.063 1.00 2.64   ? 100 TYR H CE1 1 
ATOM   5091 C CE2 . TYR C 3 110 F 180.444 202.842 209.914 1.00 3.39   ? 100 TYR H CE2 1 
ATOM   5092 C CZ  . TYR C 3 110 F 179.942 201.606 210.044 1.00 2.56   ? 100 TYR H CZ  1 
ATOM   5093 O OH  . TYR C 3 110 F 180.273 200.650 209.141 1.00 2.67   ? 100 TYR H OH  1 
ATOM   5094 N N   . TYR C 3 111 G 176.386 206.768 213.924 1.00 4.01   ? 100 TYR H N   1 
ATOM   5095 C CA  . TYR C 3 111 G 175.944 207.703 214.934 1.00 3.91   ? 100 TYR H CA  1 
ATOM   5096 C C   . TYR C 3 111 G 174.478 207.975 214.645 1.00 3.55   ? 100 TYR H C   1 
ATOM   5097 O O   . TYR C 3 111 G 173.990 207.610 213.568 1.00 4.02   ? 100 TYR H O   1 
ATOM   5098 C CB  . TYR C 3 111 G 176.783 208.981 214.921 1.00 4.92   ? 100 TYR H CB  1 
ATOM   5099 C CG  . TYR C 3 111 G 176.617 209.766 213.707 1.00 4.06   ? 100 TYR H CG  1 
ATOM   5100 C CD1 . TYR C 3 111 G 177.395 209.583 212.622 1.00 3.77   ? 100 TYR H CD1 1 
ATOM   5101 C CD2 . TYR C 3 111 G 175.681 210.669 213.693 1.00 4.96   ? 100 TYR H CD2 1 
ATOM   5102 C CE1 . TYR C 3 111 G 177.177 210.320 211.505 1.00 4.10   ? 100 TYR H CE1 1 
ATOM   5103 C CE2 . TYR C 3 111 G 175.463 211.388 212.630 1.00 4.48   ? 100 TYR H CE2 1 
ATOM   5104 C CZ  . TYR C 3 111 G 176.186 211.224 211.522 1.00 4.45   ? 100 TYR H CZ  1 
ATOM   5105 O OH  . TYR C 3 111 G 175.889 211.996 210.440 1.00 4.75   ? 100 TYR H OH  1 
ATOM   5106 N N   . PHE C 3 112 H 173.769 208.604 215.586 1.00 5.08   ? 100 PHE H N   1 
ATOM   5107 C CA  . PHE C 3 112 H 172.348 208.909 215.398 1.00 5.19   ? 100 PHE H CA  1 
ATOM   5108 C C   . PHE C 3 112 H 172.114 210.407 215.178 1.00 5.68   ? 100 PHE H C   1 
ATOM   5109 O O   . PHE C 3 112 H 172.371 211.200 216.078 1.00 7.87   ? 100 PHE H O   1 
ATOM   5110 C CB  . PHE C 3 112 H 171.578 208.446 216.631 1.00 5.35   ? 100 PHE H CB  1 
ATOM   5111 C CG  . PHE C 3 112 H 171.805 206.994 216.904 1.00 5.48   ? 100 PHE H CG  1 
ATOM   5112 C CD1 . PHE C 3 112 H 171.364 206.023 216.056 1.00 6.43   ? 100 PHE H CD1 1 
ATOM   5113 C CD2 . PHE C 3 112 H 172.567 206.605 217.994 1.00 5.11   ? 100 PHE H CD2 1 
ATOM   5114 C CE1 . PHE C 3 112 H 171.669 204.707 216.285 1.00 5.42   ? 100 PHE H CE1 1 
ATOM   5115 C CE2 . PHE C 3 112 H 172.857 205.290 218.221 1.00 4.68   ? 100 PHE H CE2 1 
ATOM   5116 C CZ  . PHE C 3 112 H 172.413 204.348 217.368 1.00 4.18   ? 100 PHE H CZ  1 
ATOM   5117 N N   . ASP C 3 113 ? 171.594 210.793 214.005 1.00 7.99   ? 101 ASP H N   1 
ATOM   5118 C CA  . ASP C 3 113 ? 171.418 212.211 213.656 1.00 8.39   ? 101 ASP H CA  1 
ATOM   5119 C C   . ASP C 3 113 ? 170.178 212.859 214.223 1.00 11.44  ? 101 ASP H C   1 
ATOM   5120 O O   . ASP C 3 113 ? 170.215 214.019 214.638 1.00 13.32  ? 101 ASP H O   1 
ATOM   5121 C CB  . ASP C 3 113 ? 171.204 212.402 212.145 1.00 10.39  ? 101 ASP H CB  1 
ATOM   5122 C CG  . ASP C 3 113 ? 172.330 212.172 211.204 1.00 10.60  ? 101 ASP H CG  1 
ATOM   5123 O OD1 . ASP C 3 113 ? 173.270 212.937 211.179 1.00 0.00   ? 101 ASP H OD1 1 
ATOM   5124 O OD2 . ASP C 3 113 ? 172.237 211.249 210.436 1.00 10.45  ? 101 ASP H OD2 1 
ATOM   5125 N N   . PHE C 3 114 ? 169.072 212.132 214.238 1.00 13.25  ? 102 PHE H N   1 
ATOM   5126 C CA  . PHE C 3 114 ? 167.834 212.765 214.677 1.00 10.99  ? 102 PHE H CA  1 
ATOM   5127 C C   . PHE C 3 114 ? 167.151 211.910 215.682 1.00 11.24  ? 102 PHE H C   1 
ATOM   5128 O O   . PHE C 3 114 ? 167.180 210.692 215.576 1.00 13.36  ? 102 PHE H O   1 
ATOM   5129 C CB  . PHE C 3 114 ? 166.885 213.034 213.514 1.00 14.01  ? 102 PHE H CB  1 
ATOM   5130 C CG  . PHE C 3 114 ? 167.478 213.889 212.442 1.00 15.67  ? 102 PHE H CG  1 
ATOM   5131 C CD1 . PHE C 3 114 ? 167.683 215.227 212.635 1.00 16.98  ? 102 PHE H CD1 1 
ATOM   5132 C CD2 . PHE C 3 114 ? 167.873 213.336 211.243 1.00 15.88  ? 102 PHE H CD2 1 
ATOM   5133 C CE1 . PHE C 3 114 ? 168.257 215.992 211.669 1.00 17.38  ? 102 PHE H CE1 1 
ATOM   5134 C CE2 . PHE C 3 114 ? 168.439 214.099 210.273 1.00 16.84  ? 102 PHE H CE2 1 
ATOM   5135 C CZ  . PHE C 3 114 ? 168.636 215.428 210.487 1.00 18.66  ? 102 PHE H CZ  1 
ATOM   5136 N N   . TRP C 3 115 ? 166.485 212.535 216.633 1.00 13.57  ? 103 TRP H N   1 
ATOM   5137 C CA  . TRP C 3 115 ? 165.757 211.811 217.665 1.00 13.39  ? 103 TRP H CA  1 
ATOM   5138 C C   . TRP C 3 115 ? 164.317 212.295 217.782 1.00 16.45  ? 103 TRP H C   1 
ATOM   5139 O O   . TRP C 3 115 ? 164.040 213.484 217.621 1.00 18.95  ? 103 TRP H O   1 
ATOM   5140 C CB  . TRP C 3 115 ? 166.471 212.024 219.002 1.00 12.88  ? 103 TRP H CB  1 
ATOM   5141 C CG  . TRP C 3 115 ? 167.871 211.440 219.087 1.00 11.23  ? 103 TRP H CG  1 
ATOM   5142 C CD1 . TRP C 3 115 ? 168.990 211.927 218.503 1.00 9.11   ? 103 TRP H CD1 1 
ATOM   5143 C CD2 . TRP C 3 115 ? 168.303 210.328 219.871 1.00 10.24  ? 103 TRP H CD2 1 
ATOM   5144 N NE1 . TRP C 3 115 ? 170.053 211.182 218.835 1.00 8.26   ? 103 TRP H NE1 1 
ATOM   5145 C CE2 . TRP C 3 115 ? 169.665 210.207 219.676 1.00 8.12   ? 103 TRP H CE2 1 
ATOM   5146 C CE3 . TRP C 3 115 ? 167.664 209.451 220.718 1.00 9.72   ? 103 TRP H CE3 1 
ATOM   5147 C CZ2 . TRP C 3 115 ? 170.400 209.241 220.293 1.00 7.25   ? 103 TRP H CZ2 1 
ATOM   5148 C CZ3 . TRP C 3 115 ? 168.405 208.490 221.340 1.00 9.45   ? 103 TRP H CZ3 1 
ATOM   5149 C CH2 . TRP C 3 115 ? 169.747 208.393 221.125 1.00 8.78   ? 103 TRP H CH2 1 
ATOM   5150 N N   . GLY C 3 116 ? 163.419 211.384 218.121 1.00 17.23  ? 104 GLY H N   1 
ATOM   5151 C CA  . GLY C 3 116 ? 162.035 211.712 218.416 1.00 20.10  ? 104 GLY H CA  1 
ATOM   5152 C C   . GLY C 3 116 ? 161.990 212.030 219.886 1.00 21.63  ? 104 GLY H C   1 
ATOM   5153 O O   . GLY C 3 116 ? 163.042 212.254 220.467 1.00 24.27  ? 104 GLY H O   1 
ATOM   5154 N N   . GLN C 3 117 ? 160.811 212.114 220.505 1.00 23.60  ? 105 GLN H N   1 
ATOM   5155 C CA  . GLN C 3 117 ? 160.822 212.478 221.924 1.00 23.87  ? 105 GLN H CA  1 
ATOM   5156 C C   . GLN C 3 117 ? 160.661 211.289 222.832 1.00 22.74  ? 105 GLN H C   1 
ATOM   5157 O O   . GLN C 3 117 ? 161.014 211.345 224.008 1.00 23.82  ? 105 GLN H O   1 
ATOM   5158 C CB  . GLN C 3 117 ? 159.872 213.611 222.235 1.00 26.63  ? 105 GLN H CB  1 
ATOM   5159 C CG  . GLN C 3 117 ? 160.272 214.887 221.486 1.00 30.06  ? 105 GLN H CG  1 
ATOM   5160 C CD  . GLN C 3 117 ? 161.762 215.343 221.800 1.00 29.91  ? 105 GLN H CD  1 
ATOM   5161 O OE1 . GLN C 3 117 ? 162.209 215.502 222.964 1.00 29.10  ? 105 GLN H OE1 1 
ATOM   5162 N NE2 . GLN C 3 117 ? 162.514 215.545 220.727 1.00 28.49  ? 105 GLN H NE2 1 
ATOM   5163 N N   . GLY C 3 118 ? 160.140 210.217 222.294 1.00 21.89  ? 106 GLY H N   1 
ATOM   5164 C CA  . GLY C 3 118 ? 160.048 208.969 223.019 1.00 18.93  ? 106 GLY H CA  1 
ATOM   5165 C C   . GLY C 3 118 ? 158.711 208.591 223.610 1.00 22.13  ? 106 GLY H C   1 
ATOM   5166 O O   . GLY C 3 118 ? 158.020 209.404 224.223 1.00 24.21  ? 106 GLY H O   1 
ATOM   5167 N N   . ALA C 3 119 ? 158.356 207.321 223.440 1.00 22.03  ? 107 ALA H N   1 
ATOM   5168 C CA  . ALA C 3 119 ? 157.125 206.780 223.986 1.00 20.32  ? 107 ALA H CA  1 
ATOM   5169 C C   . ALA C 3 119 ? 157.460 206.141 225.305 1.00 19.11  ? 107 ALA H C   1 
ATOM   5170 O O   . ALA C 3 119 ? 158.494 205.494 225.413 1.00 21.07  ? 107 ALA H O   1 
ATOM   5171 C CB  . ALA C 3 119 ? 156.509 205.762 223.043 1.00 21.48  ? 107 ALA H CB  1 
ATOM   5172 N N   . LEU C 3 120 ? 156.617 206.274 226.310 1.00 22.56  ? 108 LEU H N   1 
ATOM   5173 C CA  . LEU C 3 120 ? 156.930 205.584 227.554 1.00 22.56  ? 108 LEU H CA  1 
ATOM   5174 C C   . LEU C 3 120 ? 156.180 204.296 227.670 1.00 24.77  ? 108 LEU H C   1 
ATOM   5175 O O   . LEU C 3 120 ? 154.957 204.280 227.714 1.00 26.82  ? 108 LEU H O   1 
ATOM   5176 C CB  . LEU C 3 120 ? 156.638 206.442 228.778 1.00 24.36  ? 108 LEU H CB  1 
ATOM   5177 C CG  . LEU C 3 120 ? 156.799 205.721 230.168 1.00 25.39  ? 108 LEU H CG  1 
ATOM   5178 C CD1 . LEU C 3 120 ? 158.242 205.266 230.405 1.00 24.36  ? 108 LEU H CD1 1 
ATOM   5179 C CD2 . LEU C 3 120 ? 156.379 206.674 231.246 1.00 30.09  ? 108 LEU H CD2 1 
ATOM   5180 N N   . VAL C 3 121 ? 156.928 203.219 227.753 1.00 23.73  ? 109 VAL H N   1 
ATOM   5181 C CA  . VAL C 3 121 ? 156.360 201.900 227.837 1.00 24.64  ? 109 VAL H CA  1 
ATOM   5182 C C   . VAL C 3 121 ? 156.533 201.379 229.231 1.00 27.35  ? 109 VAL H C   1 
ATOM   5183 O O   . VAL C 3 121 ? 157.652 201.276 229.736 1.00 27.99  ? 109 VAL H O   1 
ATOM   5184 C CB  . VAL C 3 121 ? 157.051 200.984 226.839 1.00 22.45  ? 109 VAL H CB  1 
ATOM   5185 C CG1 . VAL C 3 121 ? 156.507 199.551 226.933 1.00 24.79  ? 109 VAL H CG1 1 
ATOM   5186 C CG2 . VAL C 3 121 ? 156.854 201.578 225.456 1.00 21.95  ? 109 VAL H CG2 1 
ATOM   5187 N N   . THR C 3 122 ? 155.418 201.050 229.862 1.00 31.15  ? 110 THR H N   1 
ATOM   5188 C CA  . THR C 3 122 ? 155.466 200.580 231.234 1.00 31.58  ? 110 THR H CA  1 
ATOM   5189 C C   . THR C 3 122 ? 154.987 199.166 231.352 1.00 34.31  ? 110 THR H C   1 
ATOM   5190 O O   . THR C 3 122 ? 153.889 198.838 230.910 1.00 35.47  ? 110 THR H O   1 
ATOM   5191 C CB  . THR C 3 122 ? 154.630 201.471 232.173 1.00 33.74  ? 110 THR H CB  1 
ATOM   5192 O OG1 . THR C 3 122 ? 155.143 202.800 232.156 1.00 30.18  ? 110 THR H OG1 1 
ATOM   5193 C CG2 . THR C 3 122 ? 154.700 200.933 233.598 1.00 36.15  ? 110 THR H CG2 1 
ATOM   5194 N N   . VAL C 3 123 ? 155.797 198.327 231.973 1.00 36.04  ? 111 VAL H N   1 
ATOM   5195 C CA  . VAL C 3 123 ? 155.408 196.949 232.175 1.00 37.70  ? 111 VAL H CA  1 
ATOM   5196 C C   . VAL C 3 123 ? 155.239 196.768 233.694 1.00 41.76  ? 111 VAL H C   1 
ATOM   5197 O O   . VAL C 3 123 ? 156.220 196.943 234.423 1.00 40.29  ? 111 VAL H O   1 
ATOM   5198 C CB  . VAL C 3 123 ? 156.485 196.016 231.596 1.00 35.88  ? 111 VAL H CB  1 
ATOM   5199 C CG1 . VAL C 3 123 ? 156.086 194.589 231.794 1.00 37.77  ? 111 VAL H CG1 1 
ATOM   5200 C CG2 . VAL C 3 123 ? 156.697 196.318 230.121 1.00 33.63  ? 111 VAL H CG2 1 
ATOM   5201 N N   . SER C 3 124 ? 154.002 196.446 234.161 1.00 42.75  ? 112 SER H N   1 
ATOM   5202 C CA  . SER C 3 124 ? 153.659 196.351 235.614 1.00 46.11  ? 112 SER H CA  1 
ATOM   5203 C C   . SER C 3 124 ? 153.202 194.948 236.054 1.00 45.24  ? 112 SER H C   1 
ATOM   5204 O O   . SER C 3 124 ? 153.940 194.247 236.752 1.00 47.00  ? 112 SER H O   1 
ATOM   5205 C CB  . SER C 3 124 ? 152.591 197.395 236.003 1.00 47.23  ? 112 SER H CB  1 
ATOM   5206 O OG  . SER C 3 124 ? 153.057 198.712 235.843 1.00 44.63  ? 112 SER H OG  1 
ATOM   5207 N N   . ALA D 4 1   ? 178.481 199.848 229.678 1.00 29.60  ? 3   ALA L N   1 
ATOM   5208 C CA  . ALA D 4 1   ? 179.460 199.321 228.735 1.00 29.73  ? 3   ALA L CA  1 
ATOM   5209 C C   . ALA D 4 1   ? 180.729 200.194 228.724 1.00 28.27  ? 3   ALA L C   1 
ATOM   5210 O O   . ALA D 4 1   ? 181.829 199.675 228.961 1.00 29.04  ? 3   ALA L O   1 
ATOM   5211 C CB  . ALA D 4 1   ? 178.851 199.210 227.329 1.00 25.16  ? 3   ALA L CB  1 
ATOM   5212 N N   . LEU D 4 2   ? 180.585 201.510 228.420 1.00 26.57  ? 4   LEU L N   1 
ATOM   5213 C CA  . LEU D 4 2   ? 181.686 202.490 228.386 1.00 25.95  ? 4   LEU L CA  1 
ATOM   5214 C C   . LEU D 4 2   ? 181.717 203.203 229.717 1.00 27.89  ? 4   LEU L C   1 
ATOM   5215 O O   . LEU D 4 2   ? 180.679 203.398 230.343 1.00 29.42  ? 4   LEU L O   1 
ATOM   5216 C CB  . LEU D 4 2   ? 181.474 203.496 227.254 1.00 23.42  ? 4   LEU L CB  1 
ATOM   5217 C CG  . LEU D 4 2   ? 181.404 202.930 225.839 1.00 19.82  ? 4   LEU L CG  1 
ATOM   5218 C CD1 . LEU D 4 2   ? 180.988 204.006 224.868 1.00 16.97  ? 4   LEU L CD1 1 
ATOM   5219 C CD2 . LEU D 4 2   ? 182.748 202.422 225.452 1.00 21.86  ? 4   LEU L CD2 1 
ATOM   5220 N N   . THR D 4 3   ? 182.890 203.604 230.169 1.00 28.77  ? 5   THR L N   1 
ATOM   5221 C CA  . THR D 4 3   ? 182.948 204.302 231.439 1.00 29.63  ? 5   THR L CA  1 
ATOM   5222 C C   . THR D 4 3   ? 183.234 205.772 231.283 1.00 29.07  ? 5   THR L C   1 
ATOM   5223 O O   . THR D 4 3   ? 184.231 206.177 230.699 1.00 29.87  ? 5   THR L O   1 
ATOM   5224 C CB  . THR D 4 3   ? 184.021 203.673 232.343 1.00 30.97  ? 5   THR L CB  1 
ATOM   5225 O OG1 . THR D 4 3   ? 183.684 202.306 232.582 1.00 30.93  ? 5   THR L OG1 1 
ATOM   5226 C CG2 . THR D 4 3   ? 184.094 204.408 233.679 1.00 33.18  ? 5   THR L CG2 1 
ATOM   5227 N N   . GLN D 4 4   ? 182.382 206.587 231.855 1.00 28.33  ? 6   GLN L N   1 
ATOM   5228 C CA  . GLN D 4 4   ? 182.582 208.018 231.816 1.00 29.27  ? 6   GLN L CA  1 
ATOM   5229 C C   . GLN D 4 4   ? 182.215 208.451 233.224 1.00 31.07  ? 6   GLN L C   1 
ATOM   5230 O O   . GLN D 4 4   ? 181.385 207.784 233.839 1.00 30.58  ? 6   GLN L O   1 
ATOM   5231 C CB  . GLN D 4 4   ? 181.750 208.654 230.683 1.00 26.10  ? 6   GLN L CB  1 
ATOM   5232 C CG  . GLN D 4 4   ? 180.294 208.487 230.760 1.00 25.01  ? 6   GLN L CG  1 
ATOM   5233 C CD  . GLN D 4 4   ? 179.591 209.103 229.556 1.00 20.44  ? 6   GLN L CD  1 
ATOM   5234 O OE1 . GLN D 4 4   ? 179.250 208.434 228.566 1.00 19.96  ? 6   GLN L OE1 1 
ATOM   5235 N NE2 . GLN D 4 4   ? 179.380 210.390 229.648 1.00 20.60  ? 6   GLN L NE2 1 
ATOM   5236 N N   . PRO D 4 5   ? 182.814 209.506 233.779 1.00 31.19  ? 7   PRO L N   1 
ATOM   5237 C CA  . PRO D 4 5   ? 182.586 209.950 235.133 1.00 32.70  ? 7   PRO L CA  1 
ATOM   5238 C C   . PRO D 4 5   ? 181.264 210.656 235.356 1.00 33.22  ? 7   PRO L C   1 
ATOM   5239 O O   . PRO D 4 5   ? 180.733 211.265 234.442 1.00 32.93  ? 7   PRO L O   1 
ATOM   5240 C CB  . PRO D 4 5   ? 183.731 210.940 235.326 1.00 33.40  ? 7   PRO L CB  1 
ATOM   5241 C CG  . PRO D 4 5   ? 184.004 211.468 233.941 1.00 31.45  ? 7   PRO L CG  1 
ATOM   5242 C CD  . PRO D 4 5   ? 183.765 210.306 233.026 1.00 30.32  ? 7   PRO L CD  1 
ATOM   5243 N N   . PRO D 4 6   ? 180.707 210.606 236.553 1.00 34.46  ? 8   PRO L N   1 
ATOM   5244 C CA  . PRO D 4 6   ? 179.613 211.417 237.004 1.00 35.21  ? 8   PRO L CA  1 
ATOM   5245 C C   . PRO D 4 6   ? 180.138 212.785 237.412 1.00 37.56  ? 8   PRO L C   1 
ATOM   5246 O O   . PRO D 4 6   ? 181.309 212.907 237.762 1.00 36.80  ? 8   PRO L O   1 
ATOM   5247 C CB  . PRO D 4 6   ? 179.088 210.617 238.189 1.00 37.13  ? 8   PRO L CB  1 
ATOM   5248 C CG  . PRO D 4 6   ? 180.316 209.948 238.745 1.00 38.30  ? 8   PRO L CG  1 
ATOM   5249 C CD  . PRO D 4 6   ? 181.172 209.629 237.540 1.00 35.21  ? 8   PRO L CD  1 
ATOM   5250 N N   . SER D 4 7   ? 179.258 213.762 237.461 1.00 34.71  ? 9   SER L N   1 
ATOM   5251 C CA  . SER D 4 7   ? 179.514 215.062 238.076 1.00 36.56  ? 9   SER L CA  1 
ATOM   5252 C C   . SER D 4 7   ? 180.749 215.864 237.660 1.00 36.95  ? 9   SER L C   1 
ATOM   5253 O O   . SER D 4 7   ? 181.456 216.414 238.507 1.00 40.27  ? 9   SER L O   1 
ATOM   5254 C CB  . SER D 4 7   ? 179.536 214.881 239.578 1.00 40.45  ? 9   SER L CB  1 
ATOM   5255 O OG  . SER D 4 7   ? 178.301 214.390 240.038 1.00 41.43  ? 9   SER L OG  1 
ATOM   5256 N N   . VAL D 4 8   ? 180.986 215.976 236.374 1.00 36.58  ? 11  VAL L N   1 
ATOM   5257 C CA  . VAL D 4 8   ? 182.054 216.825 235.879 1.00 36.51  ? 11  VAL L CA  1 
ATOM   5258 C C   . VAL D 4 8   ? 181.559 218.241 236.066 1.00 38.83  ? 11  VAL L C   1 
ATOM   5259 O O   . VAL D 4 8   ? 180.368 218.484 235.881 1.00 36.61  ? 11  VAL L O   1 
ATOM   5260 C CB  . VAL D 4 8   ? 182.385 216.510 234.412 1.00 35.28  ? 11  VAL L CB  1 
ATOM   5261 C CG1 . VAL D 4 8   ? 183.387 217.523 233.832 1.00 35.04  ? 11  VAL L CG1 1 
ATOM   5262 C CG2 . VAL D 4 8   ? 182.991 215.104 234.360 1.00 34.11  ? 11  VAL L CG2 1 
ATOM   5263 N N   . SER D 4 9   ? 182.406 219.147 236.527 1.00 39.67  ? 12  SER L N   1 
ATOM   5264 C CA  . SER D 4 9   ? 181.932 220.503 236.751 1.00 41.22  ? 12  SER L CA  1 
ATOM   5265 C C   . SER D 4 9   ? 182.993 221.576 236.602 1.00 43.34  ? 12  SER L C   1 
ATOM   5266 O O   . SER D 4 9   ? 184.197 221.303 236.588 1.00 41.38  ? 12  SER L O   1 
ATOM   5267 C CB  . SER D 4 9   ? 181.343 220.597 238.142 1.00 42.16  ? 12  SER L CB  1 
ATOM   5268 O OG  . SER D 4 9   ? 182.336 220.431 239.115 1.00 43.81  ? 12  SER L OG  1 
ATOM   5269 N N   . GLY D 4 10  ? 182.516 222.811 236.518 1.00 47.14  ? 13  GLY L N   1 
ATOM   5270 C CA  . GLY D 4 10  ? 183.376 224.000 236.474 1.00 44.71  ? 13  GLY L CA  1 
ATOM   5271 C C   . GLY D 4 10  ? 182.541 225.263 236.366 1.00 49.28  ? 13  GLY L C   1 
ATOM   5272 O O   . GLY D 4 10  ? 181.342 225.182 236.122 1.00 51.02  ? 13  GLY L O   1 
ATOM   5273 N N   . SER D 4 11  ? 183.165 226.418 236.545 1.00 47.49  ? 14  SER L N   1 
ATOM   5274 C CA  . SER D 4 11  ? 182.484 227.708 236.497 1.00 45.54  ? 14  SER L CA  1 
ATOM   5275 C C   . SER D 4 11  ? 182.377 228.236 235.080 1.00 41.63  ? 14  SER L C   1 
ATOM   5276 O O   . SER D 4 11  ? 183.158 227.822 234.229 1.00 55.80  ? 14  SER L O   1 
ATOM   5277 C CB  . SER D 4 11  ? 183.216 228.694 237.388 1.00 55.21  ? 14  SER L CB  1 
ATOM   5278 O OG  . SER D 4 11  ? 183.111 228.304 238.721 1.00 64.42  ? 14  SER L OG  1 
ATOM   5279 N N   . PRO D 4 12  ? 181.437 229.139 234.767 1.00 46.04  ? 15  PRO L N   1 
ATOM   5280 C CA  . PRO D 4 12  ? 181.311 229.725 233.461 1.00 48.56  ? 15  PRO L CA  1 
ATOM   5281 C C   . PRO D 4 12  ? 182.634 230.317 233.047 1.00 48.08  ? 15  PRO L C   1 
ATOM   5282 O O   . PRO D 4 12  ? 183.308 230.974 233.841 1.00 50.34  ? 15  PRO L O   1 
ATOM   5283 C CB  . PRO D 4 12  ? 180.257 230.809 233.677 1.00 45.77  ? 15  PRO L CB  1 
ATOM   5284 C CG  . PRO D 4 12  ? 179.423 230.297 234.818 1.00 50.60  ? 15  PRO L CG  1 
ATOM   5285 C CD  . PRO D 4 12  ? 180.405 229.584 235.730 1.00 48.07  ? 15  PRO L CD  1 
ATOM   5286 N N   . GLY D 4 13  ? 183.000 230.071 231.806 1.00 47.29  ? 16  GLY L N   1 
ATOM   5287 C CA  . GLY D 4 13  ? 184.244 230.543 231.232 1.00 43.56  ? 16  GLY L CA  1 
ATOM   5288 C C   . GLY D 4 13  ? 185.392 229.538 231.376 1.00 44.54  ? 16  GLY L C   1 
ATOM   5289 O O   . GLY D 4 13  ? 186.422 229.682 230.716 1.00 43.02  ? 16  GLY L O   1 
ATOM   5290 N N   . GLN D 4 14  ? 185.230 228.520 232.223 1.00 46.71  ? 17  GLN L N   1 
ATOM   5291 C CA  . GLN D 4 14  ? 186.276 227.526 232.403 1.00 44.09  ? 17  GLN L CA  1 
ATOM   5292 C C   . GLN D 4 14  ? 185.980 226.363 231.500 1.00 45.63  ? 17  GLN L C   1 
ATOM   5293 O O   . GLN D 4 14  ? 184.819 226.033 231.295 1.00 44.57  ? 17  GLN L O   1 
ATOM   5294 C CB  . GLN D 4 14  ? 186.340 227.015 233.847 1.00 47.45  ? 17  GLN L CB  1 
ATOM   5295 C CG  . GLN D 4 14  ? 186.695 228.063 234.879 1.00 51.17  ? 17  GLN L CG  1 
ATOM   5296 C CD  . GLN D 4 14  ? 186.871 227.478 236.296 1.00 53.23  ? 17  GLN L CD  1 
ATOM   5297 O OE1 . GLN D 4 14  ? 186.032 226.724 236.846 1.00 61.08  ? 17  GLN L OE1 1 
ATOM   5298 N NE2 . GLN D 4 14  ? 188.000 227.830 236.905 1.00 67.43  ? 17  GLN L NE2 1 
ATOM   5299 N N   . SER D 4 15  ? 187.004 225.706 230.988 1.00 44.34  ? 18  SER L N   1 
ATOM   5300 C CA  . SER D 4 15  ? 186.739 224.524 230.203 1.00 39.90  ? 18  SER L CA  1 
ATOM   5301 C C   . SER D 4 15  ? 186.551 223.329 231.111 1.00 39.33  ? 18  SER L C   1 
ATOM   5302 O O   . SER D 4 15  ? 187.009 223.328 232.260 1.00 40.40  ? 18  SER L O   1 
ATOM   5303 C CB  . SER D 4 15  ? 187.880 224.267 229.240 1.00 38.59  ? 18  SER L CB  1 
ATOM   5304 O OG  . SER D 4 15  ? 189.059 223.937 229.924 1.00 42.07  ? 18  SER L OG  1 
ATOM   5305 N N   . VAL D 4 16  ? 185.889 222.308 230.586 1.00 36.49  ? 19  VAL L N   1 
ATOM   5306 C CA  . VAL D 4 16  ? 185.735 221.035 231.272 1.00 37.16  ? 19  VAL L CA  1 
ATOM   5307 C C   . VAL D 4 16  ? 186.019 219.895 230.314 1.00 33.72  ? 19  VAL L C   1 
ATOM   5308 O O   . VAL D 4 16  ? 185.785 220.014 229.109 1.00 32.95  ? 19  VAL L O   1 
ATOM   5309 C CB  . VAL D 4 16  ? 184.308 220.873 231.851 1.00 37.16  ? 19  VAL L CB  1 
ATOM   5310 C CG1 . VAL D 4 16  ? 184.024 221.938 232.902 1.00 37.62  ? 19  VAL L CG1 1 
ATOM   5311 C CG2 . VAL D 4 16  ? 183.301 220.984 230.738 1.00 33.09  ? 19  VAL L CG2 1 
ATOM   5312 N N   . THR D 4 17  ? 186.441 218.758 230.841 1.00 33.16  ? 20  THR L N   1 
ATOM   5313 C CA  . THR D 4 17  ? 186.618 217.599 229.982 1.00 30.25  ? 20  THR L CA  1 
ATOM   5314 C C   . THR D 4 17  ? 185.853 216.418 230.526 1.00 29.78  ? 20  THR L C   1 
ATOM   5315 O O   . THR D 4 17  ? 185.985 216.057 231.697 1.00 29.33  ? 20  THR L O   1 
ATOM   5316 C CB  . THR D 4 17  ? 188.102 217.213 229.820 1.00 31.64  ? 20  THR L CB  1 
ATOM   5317 O OG1 . THR D 4 17  ? 188.823 218.307 229.255 1.00 32.28  ? 20  THR L OG1 1 
ATOM   5318 C CG2 . THR D 4 17  ? 188.225 216.016 228.866 1.00 29.73  ? 20  THR L CG2 1 
ATOM   5319 N N   . ILE D 4 18  ? 185.080 215.795 229.660 1.00 27.82  ? 21  ILE L N   1 
ATOM   5320 C CA  . ILE D 4 18  ? 184.338 214.615 230.022 1.00 25.50  ? 21  ILE L CA  1 
ATOM   5321 C C   . ILE D 4 18  ? 184.970 213.425 229.315 1.00 25.89  ? 21  ILE L C   1 
ATOM   5322 O O   . ILE D 4 18  ? 184.948 213.335 228.088 1.00 25.63  ? 21  ILE L O   1 
ATOM   5323 C CB  . ILE D 4 18  ? 182.866 214.784 229.617 1.00 24.05  ? 21  ILE L CB  1 
ATOM   5324 C CG1 . ILE D 4 18  ? 182.281 216.058 230.337 1.00 26.14  ? 21  ILE L CG1 1 
ATOM   5325 C CG2 . ILE D 4 18  ? 182.109 213.521 229.978 1.00 25.11  ? 21  ILE L CG2 1 
ATOM   5326 C CD1 . ILE D 4 18  ? 180.913 216.521 229.880 1.00 23.35  ? 21  ILE L CD1 1 
ATOM   5327 N N   . SER D 4 19  ? 185.565 212.520 230.076 1.00 25.50  ? 22  SER L N   1 
ATOM   5328 C CA  . SER D 4 19  ? 186.239 211.369 229.480 1.00 25.33  ? 22  SER L CA  1 
ATOM   5329 C C   . SER D 4 19  ? 185.267 210.210 229.221 1.00 25.51  ? 22  SER L C   1 
ATOM   5330 O O   . SER D 4 19  ? 184.172 210.202 229.781 1.00 27.34  ? 22  SER L O   1 
ATOM   5331 C CB  . SER D 4 19  ? 187.382 210.941 230.375 1.00 28.19  ? 22  SER L CB  1 
ATOM   5332 O OG  . SER D 4 19  ? 186.908 210.449 231.589 1.00 29.93  ? 22  SER L OG  1 
ATOM   5333 N N   . CYS D 4 20  ? 185.692 209.229 228.384 1.00 25.50  ? 23  CYS L N   1 
ATOM   5334 C CA  . CYS D 4 20  ? 184.991 207.994 228.029 1.00 23.09  ? 23  CYS L CA  1 
ATOM   5335 C C   . CYS D 4 20  ? 185.988 206.869 227.729 1.00 23.27  ? 23  CYS L C   1 
ATOM   5336 O O   . CYS D 4 20  ? 186.629 206.838 226.677 1.00 28.20  ? 23  CYS L O   1 
ATOM   5337 C CB  . CYS D 4 20  ? 184.078 208.235 226.806 1.00 22.72  ? 23  CYS L CB  1 
ATOM   5338 S SG  . CYS D 4 20  ? 183.138 206.805 226.232 1.00 26.02  ? 23  CYS L SG  1 
ATOM   5339 N N   . THR D 4 21  ? 186.116 205.918 228.633 1.00 26.11  ? 24  THR L N   1 
ATOM   5340 C CA  . THR D 4 21  ? 187.076 204.848 228.425 1.00 25.69  ? 24  THR L CA  1 
ATOM   5341 C C   . THR D 4 21  ? 186.368 203.557 228.096 1.00 26.31  ? 24  THR L C   1 
ATOM   5342 O O   . THR D 4 21  ? 185.478 203.111 228.827 1.00 27.78  ? 24  THR L O   1 
ATOM   5343 C CB  . THR D 4 21  ? 187.984 204.637 229.652 1.00 27.37  ? 24  THR L CB  1 
ATOM   5344 O OG1 . THR D 4 21  ? 188.735 205.829 229.924 1.00 28.22  ? 24  THR L OG1 1 
ATOM   5345 C CG2 . THR D 4 21  ? 188.955 203.494 229.427 1.00 27.09  ? 24  THR L CG2 1 
ATOM   5346 N N   . GLY D 4 22  ? 186.762 202.961 226.986 1.00 25.24  ? 25  GLY L N   1 
ATOM   5347 C CA  . GLY D 4 22  ? 186.198 201.713 226.524 1.00 25.79  ? 25  GLY L CA  1 
ATOM   5348 C C   . GLY D 4 22  ? 187.268 200.656 226.474 1.00 26.78  ? 25  GLY L C   1 
ATOM   5349 O O   . GLY D 4 22  ? 188.212 200.663 227.267 1.00 29.45  ? 25  GLY L O   1 
ATOM   5350 N N   . THR D 4 23  ? 187.115 199.752 225.527 1.00 27.81  ? 26  THR L N   1 
ATOM   5351 C CA  . THR D 4 23  ? 188.043 198.636 225.361 1.00 28.43  ? 26  THR L CA  1 
ATOM   5352 C C   . THR D 4 23  ? 188.707 198.636 224.000 1.00 27.19  ? 26  THR L C   1 
ATOM   5353 O O   . THR D 4 23  ? 188.516 199.569 223.207 1.00 28.01  ? 26  THR L O   1 
ATOM   5354 C CB  . THR D 4 23  ? 187.381 197.284 225.661 1.00 30.68  ? 26  THR L CB  1 
ATOM   5355 O OG1 . THR D 4 23  ? 188.395 196.263 225.685 1.00 32.93  ? 26  THR L OG1 1 
ATOM   5356 C CG2 . THR D 4 23  ? 186.322 196.943 224.650 1.00 30.49  ? 26  THR L CG2 1 
ATOM   5357 N N   . SER D 4 24  ? 189.530 197.625 223.753 1.00 30.20  ? 27  SER L N   1 
ATOM   5358 C CA  . SER D 4 24  ? 190.245 197.548 222.494 1.00 28.69  ? 27  SER L CA  1 
ATOM   5359 C C   . SER D 4 24  ? 189.320 197.245 221.331 1.00 30.17  ? 27  SER L C   1 
ATOM   5360 O O   . SER D 4 24  ? 189.327 197.966 220.340 1.00 31.75  ? 27  SER L O   1 
ATOM   5361 C CB  . SER D 4 24  ? 191.329 196.500 222.585 1.00 33.13  ? 27  SER L CB  1 
ATOM   5362 O OG  . SER D 4 24  ? 192.323 196.883 223.506 1.00 33.31  ? 27  SER L OG  1 
ATOM   5363 N N   . SER D 4 25  A 188.404 196.282 221.480 1.00 29.49  ? 27  SER L N   1 
ATOM   5364 C CA  . SER D 4 25  A 187.442 195.957 220.411 1.00 29.40  ? 27  SER L CA  1 
ATOM   5365 C C   . SER D 4 25  A 186.212 196.842 220.538 1.00 27.81  ? 27  SER L C   1 
ATOM   5366 O O   . SER D 4 25  A 185.081 196.377 220.664 1.00 27.24  ? 27  SER L O   1 
ATOM   5367 C CB  . SER D 4 25  A 187.031 194.506 220.509 1.00 33.09  ? 27  SER L CB  1 
ATOM   5368 O OG  . SER D 4 25  A 188.122 193.657 220.296 1.00 34.34  ? 27  SER L OG  1 
ATOM   5369 N N   . ASP D 4 26  B 186.483 198.123 220.538 1.00 25.73  ? 27  ASP L N   1 
ATOM   5370 C CA  . ASP D 4 26  B 185.553 199.199 220.732 1.00 21.89  ? 27  ASP L CA  1 
ATOM   5371 C C   . ASP D 4 26  B 186.166 200.517 220.271 1.00 20.79  ? 27  ASP L C   1 
ATOM   5372 O O   . ASP D 4 26  B 186.517 200.662 219.097 1.00 22.01  ? 27  ASP L O   1 
ATOM   5373 C CB  . ASP D 4 26  B 185.263 199.177 222.211 1.00 24.33  ? 27  ASP L CB  1 
ATOM   5374 C CG  . ASP D 4 26  B 184.393 200.093 222.702 1.00 24.00  ? 27  ASP L CG  1 
ATOM   5375 O OD1 . ASP D 4 26  B 183.720 200.731 221.956 1.00 20.79  ? 27  ASP L OD1 1 
ATOM   5376 O OD2 . ASP D 4 26  B 184.510 200.312 223.895 1.00 24.59  ? 27  ASP L OD2 1 
ATOM   5377 N N   . ILE D 4 27  C 186.498 201.386 221.235 1.00 22.45  ? 27  ILE L N   1 
ATOM   5378 C CA  . ILE D 4 27  C 187.117 202.667 220.964 1.00 20.42  ? 27  ILE L CA  1 
ATOM   5379 C C   . ILE D 4 27  C 188.472 202.449 220.341 1.00 22.08  ? 27  ILE L C   1 
ATOM   5380 O O   . ILE D 4 27  C 188.876 203.203 219.454 1.00 22.64  ? 27  ILE L O   1 
ATOM   5381 C CB  . ILE D 4 27  C 187.175 203.580 222.208 1.00 21.30  ? 27  ILE L CB  1 
ATOM   5382 C CG1 . ILE D 4 27  C 185.729 204.004 222.573 1.00 19.47  ? 27  ILE L CG1 1 
ATOM   5383 C CG2 . ILE D 4 27  C 188.060 204.817 221.948 1.00 22.89  ? 27  ILE L CG2 1 
ATOM   5384 C CD1 . ILE D 4 27  C 185.567 204.714 223.894 1.00 20.18  ? 27  ILE L CD1 1 
ATOM   5385 N N   . GLY D 4 28  ? 189.202 201.458 220.815 1.00 23.56  ? 28  GLY L N   1 
ATOM   5386 C CA  . GLY D 4 28  ? 190.514 201.160 220.277 1.00 23.20  ? 28  GLY L CA  1 
ATOM   5387 C C   . GLY D 4 28  ? 190.515 200.585 218.847 1.00 22.81  ? 28  GLY L C   1 
ATOM   5388 O O   . GLY D 4 28  ? 191.576 200.520 218.226 1.00 24.62  ? 28  GLY L O   1 
ATOM   5389 N N   . SER D 4 29  ? 189.371 200.113 218.324 1.00 22.78  ? 29  SER L N   1 
ATOM   5390 C CA  . SER D 4 29  ? 189.343 199.548 216.975 1.00 19.23  ? 29  SER L CA  1 
ATOM   5391 C C   . SER D 4 29  ? 188.651 200.411 215.943 1.00 17.36  ? 29  SER L C   1 
ATOM   5392 O O   . SER D 4 29  ? 189.025 200.377 214.769 1.00 17.46  ? 29  SER L O   1 
ATOM   5393 C CB  . SER D 4 29  ? 188.700 198.181 216.974 1.00 19.32  ? 29  SER L CB  1 
ATOM   5394 O OG  . SER D 4 29  ? 189.502 197.261 217.644 1.00 23.90  ? 29  SER L OG  1 
ATOM   5395 N N   . TYR D 4 30  ? 187.666 201.207 216.348 1.00 17.92  ? 30  TYR L N   1 
ATOM   5396 C CA  . TYR D 4 30  ? 186.947 201.979 215.353 1.00 14.59  ? 30  TYR L CA  1 
ATOM   5397 C C   . TYR D 4 30  ? 186.895 203.452 215.701 1.00 13.58  ? 30  TYR L C   1 
ATOM   5398 O O   . TYR D 4 30  ? 186.548 203.824 216.818 1.00 15.27  ? 30  TYR L O   1 
ATOM   5399 C CB  . TYR D 4 30  ? 185.518 201.486 215.270 1.00 12.77  ? 30  TYR L CB  1 
ATOM   5400 C CG  . TYR D 4 30  ? 185.341 200.046 215.010 1.00 11.58  ? 30  TYR L CG  1 
ATOM   5401 C CD1 . TYR D 4 30  ? 185.459 199.557 213.754 1.00 10.86  ? 30  TYR L CD1 1 
ATOM   5402 C CD2 . TYR D 4 30  ? 185.068 199.204 216.062 1.00 13.29  ? 30  TYR L CD2 1 
ATOM   5403 C CE1 . TYR D 4 30  ? 185.302 198.224 213.537 1.00 11.57  ? 30  TYR L CE1 1 
ATOM   5404 C CE2 . TYR D 4 30  ? 184.904 197.875 215.843 1.00 12.99  ? 30  TYR L CE2 1 
ATOM   5405 C CZ  . TYR D 4 30  ? 185.023 197.388 214.574 1.00 11.00  ? 30  TYR L CZ  1 
ATOM   5406 O OH  . TYR D 4 30  ? 184.867 196.051 214.345 1.00 13.34  ? 30  TYR L OH  1 
ATOM   5407 N N   . ASN D 4 31  ? 187.070 204.326 214.722 1.00 13.16  ? 31  ASN L N   1 
ATOM   5408 C CA  . ASN D 4 31  ? 186.953 205.749 215.019 1.00 13.87  ? 31  ASN L CA  1 
ATOM   5409 C C   . ASN D 4 31  ? 185.535 206.241 214.840 1.00 11.34  ? 31  ASN L C   1 
ATOM   5410 O O   . ASN D 4 31  ? 185.281 207.135 214.036 1.00 13.20  ? 31  ASN L O   1 
ATOM   5411 C CB  . ASN D 4 31  ? 187.882 206.560 214.155 1.00 18.76  ? 31  ASN L CB  1 
ATOM   5412 C CG  . ASN D 4 31  ? 189.328 206.260 214.402 1.00 20.55  ? 31  ASN L CG  1 
ATOM   5413 O OD1 . ASN D 4 31  ? 189.799 206.007 215.529 1.00 21.39  ? 31  ASN L OD1 1 
ATOM   5414 N ND2 . ASN D 4 31  ? 190.076 206.279 213.337 1.00 22.23  ? 31  ASN L ND2 1 
ATOM   5415 N N   . TYR D 4 32  ? 184.623 205.664 215.594 1.00 12.28  ? 32  TYR L N   1 
ATOM   5416 C CA  . TYR D 4 32  ? 183.225 206.018 215.494 1.00 9.64   ? 32  TYR L CA  1 
ATOM   5417 C C   . TYR D 4 32  ? 182.667 206.275 216.856 1.00 9.81   ? 32  TYR L C   1 
ATOM   5418 O O   . TYR D 4 32  ? 181.853 205.506 217.366 1.00 10.87  ? 32  TYR L O   1 
ATOM   5419 C CB  . TYR D 4 32  ? 182.388 204.949 214.812 1.00 7.59   ? 32  TYR L CB  1 
ATOM   5420 C CG  . TYR D 4 32  ? 182.846 204.535 213.455 1.00 6.36   ? 32  TYR L CG  1 
ATOM   5421 C CD1 . TYR D 4 32  ? 183.021 205.443 212.468 1.00 7.23   ? 32  TYR L CD1 1 
ATOM   5422 C CD2 . TYR D 4 32  ? 183.130 203.251 213.231 1.00 6.31   ? 32  TYR L CD2 1 
ATOM   5423 C CE1 . TYR D 4 32  ? 183.480 205.049 211.260 1.00 6.57   ? 32  TYR L CE1 1 
ATOM   5424 C CE2 . TYR D 4 32  ? 183.579 202.837 212.030 1.00 5.20   ? 32  TYR L CE2 1 
ATOM   5425 C CZ  . TYR D 4 32  ? 183.755 203.747 211.040 1.00 5.01   ? 32  TYR L CZ  1 
ATOM   5426 O OH  . TYR D 4 32  ? 184.215 203.353 209.821 1.00 7.62   ? 32  TYR L OH  1 
ATOM   5427 N N   . VAL D 4 33  ? 183.100 207.359 217.454 1.00 11.40  ? 33  VAL L N   1 
ATOM   5428 C CA  . VAL D 4 33  ? 182.670 207.695 218.786 1.00 10.41  ? 33  VAL L CA  1 
ATOM   5429 C C   . VAL D 4 33  ? 181.859 208.951 218.682 1.00 10.79  ? 33  VAL L C   1 
ATOM   5430 O O   . VAL D 4 33  ? 182.275 209.917 218.045 1.00 12.42  ? 33  VAL L O   1 
ATOM   5431 C CB  . VAL D 4 33  ? 183.858 207.905 219.736 1.00 11.82  ? 33  VAL L CB  1 
ATOM   5432 C CG1 . VAL D 4 33  ? 183.352 208.256 221.137 1.00 12.04  ? 33  VAL L CG1 1 
ATOM   5433 C CG2 . VAL D 4 33  ? 184.710 206.659 219.752 1.00 12.22  ? 33  VAL L CG2 1 
ATOM   5434 N N   . SER D 4 34  ? 180.695 208.937 219.279 1.00 11.20  ? 34  SER L N   1 
ATOM   5435 C CA  . SER D 4 34  ? 179.833 210.090 219.237 1.00 9.00   ? 34  SER L CA  1 
ATOM   5436 C C   . SER D 4 34  ? 179.408 210.483 220.621 1.00 9.06   ? 34  SER L C   1 
ATOM   5437 O O   . SER D 4 34  ? 179.473 209.693 221.566 1.00 11.46  ? 34  SER L O   1 
ATOM   5438 C CB  . SER D 4 34  ? 178.620 209.827 218.374 1.00 9.14   ? 34  SER L CB  1 
ATOM   5439 O OG  . SER D 4 34  ? 177.860 208.815 218.899 1.00 12.73  ? 34  SER L OG  1 
ATOM   5440 N N   . TRP D 4 35  ? 179.023 211.743 220.754 1.00 9.59   ? 35  TRP L N   1 
ATOM   5441 C CA  . TRP D 4 35  ? 178.545 212.279 222.011 1.00 9.18   ? 35  TRP L CA  1 
ATOM   5442 C C   . TRP D 4 35  ? 177.193 212.911 221.840 1.00 9.12   ? 35  TRP L C   1 
ATOM   5443 O O   . TRP D 4 35  ? 176.963 213.627 220.853 1.00 9.64   ? 35  TRP L O   1 
ATOM   5444 C CB  . TRP D 4 35  ? 179.515 213.316 222.567 1.00 10.52  ? 35  TRP L CB  1 
ATOM   5445 C CG  . TRP D 4 35  ? 180.832 212.758 222.979 1.00 11.62  ? 35  TRP L CG  1 
ATOM   5446 C CD1 . TRP D 4 35  ? 181.910 212.510 222.196 1.00 11.54  ? 35  TRP L CD1 1 
ATOM   5447 C CD2 . TRP D 4 35  ? 181.223 212.409 224.308 1.00 12.39  ? 35  TRP L CD2 1 
ATOM   5448 N NE1 . TRP D 4 35  ? 182.925 212.018 222.940 1.00 12.53  ? 35  TRP L NE1 1 
ATOM   5449 C CE2 . TRP D 4 35  ? 182.522 211.950 224.239 1.00 14.17  ? 35  TRP L CE2 1 
ATOM   5450 C CE3 . TRP D 4 35  ? 180.580 212.456 225.540 1.00 13.31  ? 35  TRP L CE3 1 
ATOM   5451 C CZ2 . TRP D 4 35  ? 183.195 211.536 225.349 1.00 16.96  ? 35  TRP L CZ2 1 
ATOM   5452 C CZ3 . TRP D 4 35  ? 181.261 212.054 226.651 1.00 14.93  ? 35  TRP L CZ3 1 
ATOM   5453 C CH2 . TRP D 4 35  ? 182.531 211.608 226.560 1.00 17.31  ? 35  TRP L CH2 1 
ATOM   5454 N N   . TYR D 4 36  ? 176.341 212.725 222.849 1.00 9.83   ? 36  TYR L N   1 
ATOM   5455 C CA  . TYR D 4 36  ? 174.997 213.268 222.863 1.00 9.27   ? 36  TYR L CA  1 
ATOM   5456 C C   . TYR D 4 36  ? 174.726 214.089 224.108 1.00 11.07  ? 36  TYR L C   1 
ATOM   5457 O O   . TYR D 4 36  ? 175.194 213.762 225.196 1.00 15.40  ? 36  TYR L O   1 
ATOM   5458 C CB  . TYR D 4 36  ? 173.984 212.123 222.801 1.00 9.71   ? 36  TYR L CB  1 
ATOM   5459 C CG  . TYR D 4 36  ? 174.164 211.285 221.607 1.00 8.07   ? 36  TYR L CG  1 
ATOM   5460 C CD1 . TYR D 4 36  ? 175.014 210.214 221.659 1.00 8.05   ? 36  TYR L CD1 1 
ATOM   5461 C CD2 . TYR D 4 36  ? 173.525 211.592 220.460 1.00 8.03   ? 36  TYR L CD2 1 
ATOM   5462 C CE1 . TYR D 4 36  ? 175.233 209.482 220.556 1.00 6.88   ? 36  TYR L CE1 1 
ATOM   5463 C CE2 . TYR D 4 36  ? 173.750 210.852 219.358 1.00 6.29   ? 36  TYR L CE2 1 
ATOM   5464 C CZ  . TYR D 4 36  ? 174.608 209.811 219.400 1.00 6.01   ? 36  TYR L CZ  1 
ATOM   5465 O OH  . TYR D 4 36  ? 174.851 209.096 218.271 1.00 6.68   ? 36  TYR L OH  1 
ATOM   5466 N N   . GLN D 4 37  ? 173.928 215.131 223.961 1.00 12.33  ? 37  GLN L N   1 
ATOM   5467 C CA  . GLN D 4 37  ? 173.547 216.003 225.068 1.00 14.24  ? 37  GLN L CA  1 
ATOM   5468 C C   . GLN D 4 37  ? 172.095 215.899 225.440 1.00 15.29  ? 37  GLN L C   1 
ATOM   5469 O O   . GLN D 4 37  ? 171.225 216.252 224.646 1.00 16.86  ? 37  GLN L O   1 
ATOM   5470 C CB  . GLN D 4 37  ? 173.845 217.448 224.690 1.00 18.06  ? 37  GLN L CB  1 
ATOM   5471 C CG  . GLN D 4 37  ? 173.478 218.501 225.712 1.00 19.65  ? 37  GLN L CG  1 
ATOM   5472 C CD  . GLN D 4 37  ? 173.963 219.857 225.272 1.00 21.50  ? 37  GLN L CD  1 
ATOM   5473 O OE1 . GLN D 4 37  ? 175.069 219.949 224.753 1.00 26.33  ? 37  GLN L OE1 1 
ATOM   5474 N NE2 . GLN D 4 37  ? 173.185 220.908 225.441 1.00 23.76  ? 37  GLN L NE2 1 
ATOM   5475 N N   . GLN D 4 38  ? 171.806 215.417 226.636 1.00 17.74  ? 38  GLN L N   1 
ATOM   5476 C CA  . GLN D 4 38  ? 170.422 215.276 227.036 1.00 18.10  ? 38  GLN L CA  1 
ATOM   5477 C C   . GLN D 4 38  ? 170.021 216.162 228.197 1.00 23.20  ? 38  GLN L C   1 
ATOM   5478 O O   . GLN D 4 38  ? 170.478 215.988 229.330 1.00 27.04  ? 38  GLN L O   1 
ATOM   5479 C CB  . GLN D 4 38  ? 170.142 213.832 227.424 1.00 18.71  ? 38  GLN L CB  1 
ATOM   5480 C CG  . GLN D 4 38  ? 168.722 213.580 227.803 1.00 19.07  ? 38  GLN L CG  1 
ATOM   5481 C CD  . GLN D 4 38  ? 168.412 212.150 228.103 1.00 18.49  ? 38  GLN L CD  1 
ATOM   5482 O OE1 . GLN D 4 38  ? 169.169 211.416 228.762 1.00 19.83  ? 38  GLN L OE1 1 
ATOM   5483 N NE2 . GLN D 4 38  ? 167.270 211.731 227.627 1.00 17.54  ? 38  GLN L NE2 1 
ATOM   5484 N N   . HIS D 4 39  ? 169.152 217.118 227.948 1.00 24.62  ? 39  HIS L N   1 
ATOM   5485 C CA  . HIS D 4 39  ? 168.699 217.933 229.052 1.00 28.39  ? 39  HIS L CA  1 
ATOM   5486 C C   . HIS D 4 39  ? 167.622 217.070 229.672 1.00 30.08  ? 39  HIS L C   1 
ATOM   5487 O O   . HIS D 4 39  ? 166.937 216.373 228.923 1.00 32.01  ? 39  HIS L O   1 
ATOM   5488 C CB  . HIS D 4 39  ? 168.151 219.273 228.601 1.00 30.66  ? 39  HIS L CB  1 
ATOM   5489 C CG  . HIS D 4 39  ? 169.183 220.123 228.004 1.00 28.94  ? 39  HIS L CG  1 
ATOM   5490 N ND1 . HIS D 4 39  ? 170.179 220.752 228.740 1.00 29.52  ? 39  HIS L ND1 1 
ATOM   5491 C CD2 . HIS D 4 39  ? 169.416 220.431 226.723 1.00 28.86  ? 39  HIS L CD2 1 
ATOM   5492 C CE1 . HIS D 4 39  ? 170.956 221.407 227.928 1.00 28.33  ? 39  HIS L CE1 1 
ATOM   5493 N NE2 . HIS D 4 39  ? 170.527 221.217 226.697 1.00 29.66  ? 39  HIS L NE2 1 
ATOM   5494 N N   . PRO D 4 40  ? 167.427 217.040 230.983 1.00 34.03  ? 40  PRO L N   1 
ATOM   5495 C CA  . PRO D 4 40  ? 166.391 216.242 231.584 1.00 35.06  ? 40  PRO L CA  1 
ATOM   5496 C C   . PRO D 4 40  ? 165.054 216.581 230.960 1.00 35.57  ? 40  PRO L C   1 
ATOM   5497 O O   . PRO D 4 40  ? 164.732 217.753 230.784 1.00 35.79  ? 40  PRO L O   1 
ATOM   5498 C CB  . PRO D 4 40  ? 166.456 216.684 233.047 1.00 39.01  ? 40  PRO L CB  1 
ATOM   5499 C CG  . PRO D 4 40  ? 167.897 217.117 233.241 1.00 39.23  ? 40  PRO L CG  1 
ATOM   5500 C CD  . PRO D 4 40  ? 168.281 217.772 231.927 1.00 33.36  ? 40  PRO L CD  1 
ATOM   5501 N N   . GLY D 4 41  ? 164.279 215.554 230.635 1.00 34.54  ? 41  GLY L N   1 
ATOM   5502 C CA  . GLY D 4 41  ? 162.959 215.730 230.041 1.00 35.73  ? 41  GLY L CA  1 
ATOM   5503 C C   . GLY D 4 41  ? 162.949 215.822 228.512 1.00 34.18  ? 41  GLY L C   1 
ATOM   5504 O O   . GLY D 4 41  ? 161.876 215.859 227.910 1.00 35.62  ? 41  GLY L O   1 
ATOM   5505 N N   . LYS D 4 42  ? 164.119 215.842 227.881 1.00 34.09  ? 42  LYS L N   1 
ATOM   5506 C CA  . LYS D 4 42  ? 164.212 215.969 226.427 1.00 30.59  ? 42  LYS L CA  1 
ATOM   5507 C C   . LYS D 4 42  ? 164.940 214.795 225.785 1.00 25.61  ? 42  LYS L C   1 
ATOM   5508 O O   . LYS D 4 42  ? 165.734 214.115 226.440 1.00 26.19  ? 42  LYS L O   1 
ATOM   5509 C CB  . LYS D 4 42  ? 164.959 217.255 226.078 1.00 30.86  ? 42  LYS L CB  1 
ATOM   5510 C CG  . LYS D 4 42  ? 164.357 218.545 226.650 1.00 36.31  ? 42  LYS L CG  1 
ATOM   5511 C CD  . LYS D 4 42  ? 163.002 218.874 226.048 1.00 41.99  ? 42  LYS L CD  1 
ATOM   5512 C CE  . LYS D 4 42  ? 162.486 220.204 226.566 1.00 47.98  ? 42  LYS L CE  1 
ATOM   5513 N NZ  . LYS D 4 42  ? 161.126 220.524 226.033 1.00 62.11  ? 42  LYS L NZ  1 
ATOM   5514 N N   . ALA D 4 43  ? 164.682 214.545 224.500 1.00 23.09  ? 43  ALA L N   1 
ATOM   5515 C CA  . ALA D 4 43  ? 165.461 213.528 223.805 1.00 19.08  ? 43  ALA L CA  1 
ATOM   5516 C C   . ALA D 4 43  ? 166.898 214.025 223.635 1.00 19.12  ? 43  ALA L C   1 
ATOM   5517 O O   . ALA D 4 43  ? 167.085 215.237 223.572 1.00 19.91  ? 43  ALA L O   1 
ATOM   5518 C CB  . ALA D 4 43  ? 164.868 213.225 222.474 1.00 19.74  ? 43  ALA L CB  1 
ATOM   5519 N N   . PRO D 4 44  ? 167.920 213.152 223.569 1.00 15.44  ? 44  PRO L N   1 
ATOM   5520 C CA  . PRO D 4 44  ? 169.314 213.497 223.339 1.00 12.53  ? 44  PRO L CA  1 
ATOM   5521 C C   . PRO D 4 44  ? 169.560 214.193 222.010 1.00 11.10  ? 44  PRO L C   1 
ATOM   5522 O O   . PRO D 4 44  ? 168.959 213.839 221.004 1.00 13.77  ? 44  PRO L O   1 
ATOM   5523 C CB  . PRO D 4 44  ? 169.978 212.124 223.315 1.00 11.42  ? 44  PRO L CB  1 
ATOM   5524 C CG  . PRO D 4 44  ? 169.062 211.228 224.075 1.00 12.93  ? 44  PRO L CG  1 
ATOM   5525 C CD  . PRO D 4 44  ? 167.698 211.714 223.790 1.00 12.61  ? 44  PRO L CD  1 
ATOM   5526 N N   . LYS D 4 45  ? 170.490 215.134 221.992 1.00 12.83  ? 45  LYS L N   1 
ATOM   5527 C CA  . LYS D 4 45  ? 170.904 215.824 220.776 1.00 11.26  ? 45  LYS L CA  1 
ATOM   5528 C C   . LYS D 4 45  ? 172.304 215.380 220.373 1.00 10.97  ? 45  LYS L C   1 
ATOM   5529 O O   . LYS D 4 45  ? 173.162 215.211 221.228 1.00 13.62  ? 45  LYS L O   1 
ATOM   5530 C CB  . LYS D 4 45  ? 170.883 217.331 221.019 1.00 13.05  ? 45  LYS L CB  1 
ATOM   5531 C CG  . LYS D 4 45  ? 171.257 218.176 219.832 1.00 15.43  ? 45  LYS L CG  1 
ATOM   5532 C CD  . LYS D 4 45  ? 171.174 219.643 220.150 1.00 17.18  ? 45  LYS L CD  1 
ATOM   5533 C CE  . LYS D 4 45  ? 171.578 220.460 218.953 1.00 23.09  ? 45  LYS L CE  1 
ATOM   5534 N NZ  . LYS D 4 45  ? 171.567 221.925 219.238 1.00 30.88  ? 45  LYS L NZ  1 
ATOM   5535 N N   . LEU D 4 46  ? 172.582 215.218 219.087 1.00 10.29  ? 46  LEU L N   1 
ATOM   5536 C CA  . LEU D 4 46  ? 173.952 214.870 218.690 1.00 9.43   ? 46  LEU L CA  1 
ATOM   5537 C C   . LEU D 4 46  ? 174.860 216.076 218.779 1.00 11.12  ? 46  LEU L C   1 
ATOM   5538 O O   . LEU D 4 46  ? 174.541 217.122 218.218 1.00 13.71  ? 46  LEU L O   1 
ATOM   5539 C CB  . LEU D 4 46  ? 173.990 214.376 217.240 1.00 9.19   ? 46  LEU L CB  1 
ATOM   5540 C CG  . LEU D 4 46  ? 175.370 213.949 216.668 1.00 7.39   ? 46  LEU L CG  1 
ATOM   5541 C CD1 . LEU D 4 46  ? 175.865 212.711 217.343 1.00 7.33   ? 46  LEU L CD1 1 
ATOM   5542 C CD2 . LEU D 4 46  ? 175.228 213.733 215.220 1.00 6.79   ? 46  LEU L CD2 1 
ATOM   5543 N N   . MET D 4 47  ? 176.009 215.931 219.440 1.00 11.54  ? 47  MET L N   1 
ATOM   5544 C CA  . MET D 4 47  ? 176.953 217.033 219.532 1.00 11.80  ? 47  MET L CA  1 
ATOM   5545 C C   . MET D 4 47  ? 178.219 216.757 218.732 1.00 11.61  ? 47  MET L C   1 
ATOM   5546 O O   . MET D 4 47  ? 178.766 217.643 218.088 1.00 15.13  ? 47  MET L O   1 
ATOM   5547 C CB  . MET D 4 47  ? 177.328 217.282 220.986 1.00 12.47  ? 47  MET L CB  1 
ATOM   5548 C CG  . MET D 4 47  ? 176.159 217.679 221.876 1.00 14.26  ? 47  MET L CG  1 
ATOM   5549 S SD  . MET D 4 47  ? 175.215 219.103 221.325 1.00 17.94  ? 47  MET L SD  1 
ATOM   5550 C CE  . MET D 4 47  ? 176.325 220.447 221.565 1.00 23.72  ? 47  MET L CE  1 
ATOM   5551 N N   . ILE D 4 48  ? 178.715 215.529 218.837 1.00 11.43  ? 48  ILE L N   1 
ATOM   5552 C CA  . ILE D 4 48  ? 179.962 215.082 218.198 1.00 10.09  ? 48  ILE L CA  1 
ATOM   5553 C C   . ILE D 4 48  ? 179.793 213.723 217.549 1.00 9.72   ? 48  ILE L C   1 
ATOM   5554 O O   . ILE D 4 48  ? 179.084 212.884 218.093 1.00 13.82  ? 48  ILE L O   1 
ATOM   5555 C CB  . ILE D 4 48  ? 181.154 215.021 219.204 1.00 11.52  ? 48  ILE L CB  1 
ATOM   5556 C CG1 . ILE D 4 48  ? 181.479 216.416 219.812 1.00 12.82  ? 48  ILE L CG1 1 
ATOM   5557 C CG2 . ILE D 4 48  ? 182.416 214.385 218.595 1.00 13.12  ? 48  ILE L CG2 1 
ATOM   5558 C CD1 . ILE D 4 48  ? 182.019 217.462 218.868 1.00 14.09  ? 48  ILE L CD1 1 
ATOM   5559 N N   . TYR D 4 49  ? 180.430 213.492 216.410 1.00 10.06  ? 49  TYR L N   1 
ATOM   5560 C CA  . TYR D 4 49  ? 180.418 212.181 215.775 1.00 8.40   ? 49  TYR L CA  1 
ATOM   5561 C C   . TYR D 4 49  ? 181.756 211.868 215.121 1.00 11.00  ? 49  TYR L C   1 
ATOM   5562 O O   . TYR D 4 49  ? 182.587 212.742 214.892 1.00 14.14  ? 49  TYR L O   1 
ATOM   5563 C CB  . TYR D 4 49  ? 179.262 212.048 214.808 1.00 7.71   ? 49  TYR L CB  1 
ATOM   5564 C CG  . TYR D 4 49  ? 179.296 212.912 213.646 1.00 6.93   ? 49  TYR L CG  1 
ATOM   5565 C CD1 . TYR D 4 49  ? 178.770 214.153 213.705 1.00 8.76   ? 49  TYR L CD1 1 
ATOM   5566 C CD2 . TYR D 4 49  ? 179.840 212.460 212.509 1.00 6.94   ? 49  TYR L CD2 1 
ATOM   5567 C CE1 . TYR D 4 49  ? 178.796 214.932 212.612 1.00 8.92   ? 49  TYR L CE1 1 
ATOM   5568 C CE2 . TYR D 4 49  ? 179.875 213.231 211.419 1.00 6.10   ? 49  TYR L CE2 1 
ATOM   5569 C CZ  . TYR D 4 49  ? 179.349 214.474 211.471 1.00 7.27   ? 49  TYR L CZ  1 
ATOM   5570 O OH  . TYR D 4 49  ? 179.384 215.259 210.360 1.00 12.36  ? 49  TYR L OH  1 
ATOM   5571 N N   . ASP D 4 50  ? 182.029 210.592 214.879 1.00 12.67  ? 50  ASP L N   1 
ATOM   5572 C CA  . ASP D 4 50  ? 183.292 210.199 214.256 1.00 12.18  ? 50  ASP L CA  1 
ATOM   5573 C C   . ASP D 4 50  ? 184.484 210.791 214.987 1.00 13.34  ? 50  ASP L C   1 
ATOM   5574 O O   . ASP D 4 50  ? 185.435 211.275 214.370 1.00 16.25  ? 50  ASP L O   1 
ATOM   5575 C CB  . ASP D 4 50  ? 183.337 210.563 212.786 1.00 13.11  ? 50  ASP L CB  1 
ATOM   5576 C CG  . ASP D 4 50  ? 182.306 209.834 212.034 1.00 14.73  ? 50  ASP L CG  1 
ATOM   5577 O OD1 . ASP D 4 50  ? 181.812 208.855 212.552 1.00 12.07  ? 50  ASP L OD1 1 
ATOM   5578 O OD2 . ASP D 4 50  ? 181.986 210.236 210.947 1.00 13.22  ? 50  ASP L OD2 1 
ATOM   5579 N N   . VAL D 4 51  ? 184.408 210.762 216.313 1.00 14.72  ? 51  VAL L N   1 
ATOM   5580 C CA  . VAL D 4 51  ? 185.383 211.221 217.282 1.00 14.53  ? 51  VAL L CA  1 
ATOM   5581 C C   . VAL D 4 51  ? 185.519 212.747 217.325 1.00 15.65  ? 51  VAL L C   1 
ATOM   5582 O O   . VAL D 4 51  ? 185.381 213.329 218.390 1.00 17.63  ? 51  VAL L O   1 
ATOM   5583 C CB  . VAL D 4 51  ? 186.759 210.595 217.030 1.00 16.85  ? 51  VAL L CB  1 
ATOM   5584 C CG1 . VAL D 4 51  ? 187.759 211.137 218.051 1.00 21.12  ? 51  VAL L CG1 1 
ATOM   5585 C CG2 . VAL D 4 51  ? 186.662 209.083 217.070 1.00 16.03  ? 51  VAL L CG2 1 
ATOM   5586 N N   . THR D 4 52  ? 185.840 213.380 216.193 1.00 17.47  ? 52  THR L N   1 
ATOM   5587 C CA  . THR D 4 52  ? 186.101 214.819 216.134 1.00 16.44  ? 52  THR L CA  1 
ATOM   5588 C C   . THR D 4 52  ? 185.125 215.736 215.383 1.00 15.81  ? 52  THR L C   1 
ATOM   5589 O O   . THR D 4 52  ? 185.346 216.948 215.375 1.00 17.01  ? 52  THR L O   1 
ATOM   5590 C CB  . THR D 4 52  ? 187.460 215.071 215.459 1.00 19.17  ? 52  THR L CB  1 
ATOM   5591 O OG1 . THR D 4 52  ? 187.424 214.599 214.103 1.00 18.92  ? 52  THR L OG1 1 
ATOM   5592 C CG2 . THR D 4 52  ? 188.532 214.322 216.169 1.00 19.79  ? 52  THR L CG2 1 
ATOM   5593 N N   . GLN D 4 53  ? 184.091 215.218 214.726 1.00 16.07  ? 53  GLN L N   1 
ATOM   5594 C CA  . GLN D 4 53  ? 183.242 216.067 213.894 1.00 14.56  ? 53  GLN L CA  1 
ATOM   5595 C C   . GLN D 4 53  ? 182.063 216.606 214.630 1.00 12.67  ? 53  GLN L C   1 
ATOM   5596 O O   . GLN D 4 53  ? 181.529 215.951 215.509 1.00 14.52  ? 53  GLN L O   1 
ATOM   5597 C CB  . GLN D 4 53  ? 182.694 215.282 212.717 1.00 13.14  ? 53  GLN L CB  1 
ATOM   5598 C CG  . GLN D 4 53  ? 183.706 214.694 211.838 1.00 14.08  ? 53  GLN L CG  1 
ATOM   5599 C CD  . GLN D 4 53  ? 184.519 215.716 211.217 1.00 19.40  ? 53  GLN L CD  1 
ATOM   5600 O OE1 . GLN D 4 53  ? 183.993 216.642 210.601 1.00 21.10  ? 53  GLN L OE1 1 
ATOM   5601 N NE2 . GLN D 4 53  ? 185.817 215.597 211.363 1.00 22.13  ? 53  GLN L NE2 1 
ATOM   5602 N N   . ARG D 4 54  ? 181.565 217.755 214.215 1.00 14.51  ? 54  ARG L N   1 
ATOM   5603 C CA  . ARG D 4 54  ? 180.357 218.241 214.848 1.00 15.32  ? 54  ARG L CA  1 
ATOM   5604 C C   . ARG D 4 54  ? 179.358 218.499 213.739 1.00 17.04  ? 54  ARG L C   1 
ATOM   5605 O O   . ARG D 4 54  ? 179.773 218.865 212.643 1.00 17.62  ? 54  ARG L O   1 
ATOM   5606 C CB  . ARG D 4 54  ? 180.645 219.506 215.633 1.00 18.23  ? 54  ARG L CB  1 
ATOM   5607 C CG  . ARG D 4 54  ? 181.051 220.707 214.821 1.00 22.98  ? 54  ARG L CG  1 
ATOM   5608 C CD  . ARG D 4 54  ? 181.316 221.892 215.691 1.00 26.95  ? 54  ARG L CD  1 
ATOM   5609 N NE  . ARG D 4 54  ? 182.464 221.679 216.566 1.00 28.39  ? 54  ARG L NE  1 
ATOM   5610 C CZ  . ARG D 4 54  ? 183.749 221.869 216.227 1.00 31.30  ? 54  ARG L CZ  1 
ATOM   5611 N NH1 . ARG D 4 54  ? 184.095 222.287 215.022 1.00 33.06  ? 54  ARG L NH1 1 
ATOM   5612 N NH2 . ARG D 4 54  ? 184.655 221.621 217.141 1.00 31.06  ? 54  ARG L NH2 1 
ATOM   5613 N N   . PRO D 4 55  ? 178.059 218.310 213.969 1.00 16.57  ? 55  PRO L N   1 
ATOM   5614 C CA  . PRO D 4 55  ? 177.005 218.563 213.035 1.00 17.81  ? 55  PRO L CA  1 
ATOM   5615 C C   . PRO D 4 55  ? 176.765 220.034 212.871 1.00 23.75  ? 55  PRO L C   1 
ATOM   5616 O O   . PRO D 4 55  ? 177.060 220.826 213.769 1.00 26.68  ? 55  PRO L O   1 
ATOM   5617 C CB  . PRO D 4 55  ? 175.821 217.862 213.685 1.00 16.38  ? 55  PRO L CB  1 
ATOM   5618 C CG  . PRO D 4 55  ? 176.111 217.914 215.130 1.00 14.99  ? 55  PRO L CG  1 
ATOM   5619 C CD  . PRO D 4 55  ? 177.592 217.789 215.242 1.00 14.84  ? 55  PRO L CD  1 
ATOM   5620 N N   . SER D 4 56  ? 176.167 220.399 211.761 1.00 25.46  ? 56  SER L N   1 
ATOM   5621 C CA  . SER D 4 56  ? 175.754 221.765 211.611 1.00 28.54  ? 56  SER L CA  1 
ATOM   5622 C C   . SER D 4 56  ? 174.721 221.983 212.681 1.00 29.32  ? 56  SER L C   1 
ATOM   5623 O O   . SER D 4 56  ? 173.957 221.072 212.997 1.00 28.80  ? 56  SER L O   1 
ATOM   5624 C CB  . SER D 4 56  ? 175.151 221.998 210.244 1.00 31.62  ? 56  SER L CB  1 
ATOM   5625 O OG  . SER D 4 56  ? 176.094 221.781 209.232 1.00 36.06  ? 56  SER L OG  1 
ATOM   5626 N N   . GLY D 4 57  ? 174.669 223.175 213.239 1.00 30.95  ? 57  GLY L N   1 
ATOM   5627 C CA  . GLY D 4 57  ? 173.686 223.453 214.269 1.00 31.27  ? 57  GLY L CA  1 
ATOM   5628 C C   . GLY D 4 57  ? 174.261 223.463 215.682 1.00 31.04  ? 57  GLY L C   1 
ATOM   5629 O O   . GLY D 4 57  ? 173.574 223.897 216.612 1.00 31.50  ? 57  GLY L O   1 
ATOM   5630 N N   . VAL D 4 58  ? 175.510 223.023 215.874 1.00 29.50  ? 58  VAL L N   1 
ATOM   5631 C CA  . VAL D 4 58  ? 176.045 223.110 217.231 1.00 30.35  ? 58  VAL L CA  1 
ATOM   5632 C C   . VAL D 4 58  ? 177.247 224.019 217.203 1.00 29.71  ? 58  VAL L C   1 
ATOM   5633 O O   . VAL D 4 58  ? 177.838 224.264 216.151 1.00 29.62  ? 58  VAL L O   1 
ATOM   5634 C CB  . VAL D 4 58  ? 176.426 221.745 217.842 1.00 25.97  ? 58  VAL L CB  1 
ATOM   5635 C CG1 . VAL D 4 58  ? 175.228 220.878 217.866 1.00 24.26  ? 58  VAL L CG1 1 
ATOM   5636 C CG2 . VAL D 4 58  ? 177.530 221.114 217.130 1.00 23.20  ? 58  VAL L CG2 1 
ATOM   5637 N N   . SER D 4 59  ? 177.589 224.534 218.367 1.00 30.59  ? 59  SER L N   1 
ATOM   5638 C CA  . SER D 4 59  ? 178.694 225.448 218.510 1.00 32.32  ? 59  SER L CA  1 
ATOM   5639 C C   . SER D 4 59  ? 180.042 224.781 218.460 1.00 31.81  ? 59  SER L C   1 
ATOM   5640 O O   . SER D 4 59  ? 180.192 223.575 218.675 1.00 32.95  ? 59  SER L O   1 
ATOM   5641 C CB  . SER D 4 59  ? 178.534 226.215 219.798 1.00 31.11  ? 59  SER L CB  1 
ATOM   5642 O OG  . SER D 4 59  ? 178.652 225.364 220.887 1.00 31.11  ? 59  SER L OG  1 
ATOM   5643 N N   . ASP D 4 60  ? 181.059 225.601 218.270 1.00 33.69  ? 60  ASP L N   1 
ATOM   5644 C CA  . ASP D 4 60  ? 182.429 225.163 218.176 1.00 33.67  ? 60  ASP L CA  1 
ATOM   5645 C C   . ASP D 4 60  ? 183.111 225.152 219.517 1.00 32.89  ? 60  ASP L C   1 
ATOM   5646 O O   . ASP D 4 60  ? 184.320 224.956 219.623 1.00 33.21  ? 60  ASP L O   1 
ATOM   5647 C CB  . ASP D 4 60  ? 183.158 226.011 217.148 1.00 36.12  ? 60  ASP L CB  1 
ATOM   5648 C CG  . ASP D 4 60  ? 183.095 227.456 217.499 1.00 38.33  ? 60  ASP L CG  1 
ATOM   5649 O OD1 . ASP D 4 60  ? 182.259 227.781 218.329 1.00 38.58  ? 60  ASP L OD1 1 
ATOM   5650 O OD2 . ASP D 4 60  ? 183.826 228.238 216.946 1.00 45.04  ? 60  ASP L OD2 1 
ATOM   5651 N N   . ARG D 4 61  ? 182.301 225.281 220.559 1.00 31.51  ? 61  ARG L N   1 
ATOM   5652 C CA  . ARG D 4 61  ? 182.784 225.188 221.904 1.00 28.21  ? 61  ARG L CA  1 
ATOM   5653 C C   . ARG D 4 61  ? 182.888 223.719 222.261 1.00 26.60  ? 61  ARG L C   1 
ATOM   5654 O O   . ARG D 4 61  ? 183.491 223.369 223.268 1.00 29.06  ? 61  ARG L O   1 
ATOM   5655 C CB  . ARG D 4 61  ? 181.860 225.869 222.885 1.00 31.20  ? 61  ARG L CB  1 
ATOM   5656 C CG  . ARG D 4 61  ? 181.746 227.354 222.689 1.00 31.75  ? 61  ARG L CG  1 
ATOM   5657 C CD  . ARG D 4 61  ? 181.003 228.017 223.776 1.00 32.96  ? 61  ARG L CD  1 
ATOM   5658 N NE  . ARG D 4 61  ? 179.599 227.631 223.877 1.00 34.32  ? 61  ARG L NE  1 
ATOM   5659 C CZ  . ARG D 4 61  ? 179.076 226.826 224.847 1.00 32.48  ? 61  ARG L CZ  1 
ATOM   5660 N NH1 . ARG D 4 61  ? 179.843 226.287 225.766 1.00 31.88  ? 61  ARG L NH1 1 
ATOM   5661 N NH2 . ARG D 4 61  ? 177.777 226.589 224.877 1.00 33.20  ? 61  ARG L NH2 1 
ATOM   5662 N N   . PHE D 4 62  ? 182.278 222.854 221.437 1.00 28.46  ? 62  PHE L N   1 
ATOM   5663 C CA  . PHE D 4 62  ? 182.282 221.415 221.659 1.00 24.53  ? 62  PHE L CA  1 
ATOM   5664 C C   . PHE D 4 62  ? 183.255 220.761 220.694 1.00 23.76  ? 62  PHE L C   1 
ATOM   5665 O O   . PHE D 4 62  ? 183.097 220.854 219.469 1.00 27.53  ? 62  PHE L O   1 
ATOM   5666 C CB  . PHE D 4 62  ? 180.873 220.847 221.470 1.00 23.58  ? 62  PHE L CB  1 
ATOM   5667 C CG  . PHE D 4 62  ? 179.920 221.287 222.530 1.00 23.59  ? 62  PHE L CG  1 
ATOM   5668 C CD1 . PHE D 4 62  ? 179.277 222.486 222.434 1.00 25.43  ? 62  PHE L CD1 1 
ATOM   5669 C CD2 . PHE D 4 62  ? 179.667 220.504 223.621 1.00 22.46  ? 62  PHE L CD2 1 
ATOM   5670 C CE1 . PHE D 4 62  ? 178.415 222.902 223.409 1.00 26.87  ? 62  PHE L CE1 1 
ATOM   5671 C CE2 . PHE D 4 62  ? 178.802 220.917 224.593 1.00 22.98  ? 62  PHE L CE2 1 
ATOM   5672 C CZ  . PHE D 4 62  ? 178.181 222.116 224.491 1.00 25.35  ? 62  PHE L CZ  1 
ATOM   5673 N N   . SER D 4 63  ? 184.250 220.072 221.242 1.00 24.39  ? 63  SER L N   1 
ATOM   5674 C CA  . SER D 4 63  ? 185.292 219.435 220.442 1.00 23.46  ? 63  SER L CA  1 
ATOM   5675 C C   . SER D 4 63  ? 185.687 218.057 220.945 1.00 21.84  ? 63  SER L C   1 
ATOM   5676 O O   . SER D 4 63  ? 185.945 217.866 222.133 1.00 23.49  ? 63  SER L O   1 
ATOM   5677 C CB  . SER D 4 63  ? 186.518 220.308 220.443 1.00 26.81  ? 63  SER L CB  1 
ATOM   5678 O OG  . SER D 4 63  ? 187.555 219.699 219.741 1.00 32.78  ? 63  SER L OG  1 
ATOM   5679 N N   . GLY D 4 64  ? 185.658 217.067 220.065 1.00 20.36  ? 64  GLY L N   1 
ATOM   5680 C CA  . GLY D 4 64  ? 186.012 215.715 220.481 1.00 20.25  ? 64  GLY L CA  1 
ATOM   5681 C C   . GLY D 4 64  ? 187.454 215.341 220.163 1.00 22.08  ? 64  GLY L C   1 
ATOM   5682 O O   . GLY D 4 64  ? 188.078 215.915 219.265 1.00 22.85  ? 64  GLY L O   1 
ATOM   5683 N N   . SER D 4 65  ? 187.958 214.329 220.862 1.00 22.10  ? 65  SER L N   1 
ATOM   5684 C CA  . SER D 4 65  ? 189.287 213.772 220.605 1.00 22.97  ? 65  SER L CA  1 
ATOM   5685 C C   . SER D 4 65  ? 189.424 212.366 221.185 1.00 23.47  ? 65  SER L C   1 
ATOM   5686 O O   . SER D 4 65  ? 188.567 211.921 221.955 1.00 25.05  ? 65  SER L O   1 
ATOM   5687 C CB  . SER D 4 65  ? 190.357 214.668 221.178 1.00 24.71  ? 65  SER L CB  1 
ATOM   5688 O OG  . SER D 4 65  ? 190.318 214.664 222.570 1.00 25.22  ? 65  SER L OG  1 
ATOM   5689 N N   . LYS D 4 66  ? 190.489 211.648 220.813 1.00 24.89  ? 66  LYS L N   1 
ATOM   5690 C CA  . LYS D 4 66  ? 190.750 210.345 221.433 1.00 25.58  ? 66  LYS L CA  1 
ATOM   5691 C C   . LYS D 4 66  ? 192.212 209.942 221.387 1.00 29.18  ? 66  LYS L C   1 
ATOM   5692 O O   . LYS D 4 66  ? 192.968 210.401 220.527 1.00 29.40  ? 66  LYS L O   1 
ATOM   5693 C CB  . LYS D 4 66  ? 189.984 209.217 220.762 1.00 25.20  ? 66  LYS L CB  1 
ATOM   5694 C CG  . LYS D 4 66  ? 190.488 208.902 219.379 1.00 26.02  ? 66  LYS L CG  1 
ATOM   5695 C CD  . LYS D 4 66  ? 189.701 207.827 218.725 1.00 25.88  ? 66  LYS L CD  1 
ATOM   5696 C CE  . LYS D 4 66  ? 190.171 206.464 219.136 1.00 22.99  ? 66  LYS L CE  1 
ATOM   5697 N NZ  . LYS D 4 66  ? 189.478 205.441 218.384 1.00 21.95  ? 66  LYS L NZ  1 
ATOM   5698 N N   . SER D 4 67  ? 192.571 209.022 222.273 1.00 28.27  ? 67  SER L N   1 
ATOM   5699 C CA  . SER D 4 67  ? 193.869 208.366 222.293 1.00 30.53  ? 67  SER L CA  1 
ATOM   5700 C C   . SER D 4 67  ? 193.727 206.977 222.906 1.00 29.51  ? 67  SER L C   1 
ATOM   5701 O O   . SER D 4 67  ? 193.105 206.818 223.960 1.00 29.48  ? 67  SER L O   1 
ATOM   5702 C CB  . SER D 4 67  ? 194.869 209.172 223.077 1.00 34.15  ? 67  SER L CB  1 
ATOM   5703 O OG  . SER D 4 67  ? 196.106 208.518 223.111 1.00 37.36  ? 67  SER L OG  1 
ATOM   5704 N N   . GLY D 4 68  ? 194.307 205.964 222.283 1.00 30.07  ? 68  GLY L N   1 
ATOM   5705 C CA  . GLY D 4 68  ? 194.197 204.623 222.841 1.00 29.74  ? 68  GLY L CA  1 
ATOM   5706 C C   . GLY D 4 68  ? 192.742 204.191 222.886 1.00 27.35  ? 68  GLY L C   1 
ATOM   5707 O O   . GLY D 4 68  ? 192.051 204.231 221.870 1.00 27.08  ? 68  GLY L O   1 
ATOM   5708 N N   . ASN D 4 69  ? 192.281 203.761 224.064 1.00 27.25  ? 69  ASN L N   1 
ATOM   5709 C CA  . ASN D 4 69  ? 190.909 203.307 224.236 1.00 25.52  ? 69  ASN L CA  1 
ATOM   5710 C C   . ASN D 4 69  ? 190.064 204.386 224.911 1.00 24.26  ? 69  ASN L C   1 
ATOM   5711 O O   . ASN D 4 69  ? 188.959 204.118 225.390 1.00 27.23  ? 69  ASN L O   1 
ATOM   5712 C CB  . ASN D 4 69  ? 190.860 202.030 225.051 1.00 26.88  ? 69  ASN L CB  1 
ATOM   5713 C CG  . ASN D 4 69  ? 191.548 200.881 224.380 1.00 28.24  ? 69  ASN L CG  1 
ATOM   5714 O OD1 . ASN D 4 69  ? 191.808 200.895 223.183 1.00 28.32  ? 69  ASN L OD1 1 
ATOM   5715 N ND2 . ASN D 4 69  ? 191.833 199.859 225.133 1.00 29.23  ? 69  ASN L ND2 1 
ATOM   5716 N N   . THR D 4 70  ? 190.588 205.607 225.003 1.00 25.77  ? 70  THR L N   1 
ATOM   5717 C CA  . THR D 4 70  ? 189.842 206.672 225.661 1.00 24.53  ? 70  THR L CA  1 
ATOM   5718 C C   . THR D 4 70  ? 189.497 207.830 224.750 1.00 25.28  ? 70  THR L C   1 
ATOM   5719 O O   . THR D 4 70  ? 190.339 208.417 224.072 1.00 27.50  ? 70  THR L O   1 
ATOM   5720 C CB  . THR D 4 70  ? 190.594 207.218 226.894 1.00 26.68  ? 70  THR L CB  1 
ATOM   5721 O OG1 . THR D 4 70  ? 190.784 206.160 227.833 1.00 27.19  ? 70  THR L OG1 1 
ATOM   5722 C CG2 . THR D 4 70  ? 189.785 208.335 227.579 1.00 26.45  ? 70  THR L CG2 1 
ATOM   5723 N N   . ALA D 4 71  ? 188.231 208.180 224.770 1.00 25.04  ? 71  ALA L N   1 
ATOM   5724 C CA  . ALA D 4 71  ? 187.691 209.280 224.013 1.00 22.76  ? 71  ALA L CA  1 
ATOM   5725 C C   . ALA D 4 71  ? 187.273 210.369 224.976 1.00 22.72  ? 71  ALA L C   1 
ATOM   5726 O O   . ALA D 4 71  ? 186.909 210.090 226.119 1.00 26.56  ? 71  ALA L O   1 
ATOM   5727 C CB  . ALA D 4 71  ? 186.539 208.813 223.174 1.00 20.80  ? 71  ALA L CB  1 
ATOM   5728 N N   . SER D 4 72  ? 187.266 211.608 224.533 1.00 21.29  ? 72  SER L N   1 
ATOM   5729 C CA  . SER D 4 72  ? 186.784 212.656 225.410 1.00 20.73  ? 72  SER L CA  1 
ATOM   5730 C C   . SER D 4 72  ? 186.112 213.808 224.689 1.00 20.93  ? 72  SER L C   1 
ATOM   5731 O O   . SER D 4 72  ? 186.338 214.076 223.500 1.00 22.34  ? 72  SER L O   1 
ATOM   5732 C CB  . SER D 4 72  ? 187.919 213.184 226.247 1.00 24.03  ? 72  SER L CB  1 
ATOM   5733 O OG  . SER D 4 72  ? 188.880 213.811 225.462 1.00 23.97  ? 72  SER L OG  1 
ATOM   5734 N N   . LEU D 4 73  ? 185.258 214.495 225.439 1.00 19.87  ? 73  LEU L N   1 
ATOM   5735 C CA  . LEU D 4 73  ? 184.576 215.691 224.988 1.00 18.73  ? 73  LEU L CA  1 
ATOM   5736 C C   . LEU D 4 73  ? 185.052 216.913 225.736 1.00 22.87  ? 73  LEU L C   1 
ATOM   5737 O O   . LEU D 4 73  ? 184.959 216.991 226.963 1.00 25.06  ? 73  LEU L O   1 
ATOM   5738 C CB  . LEU D 4 73  ? 183.064 215.549 225.195 1.00 16.81  ? 73  LEU L CB  1 
ATOM   5739 C CG  . LEU D 4 73  ? 182.168 216.777 224.872 1.00 17.10  ? 73  LEU L CG  1 
ATOM   5740 C CD1 . LEU D 4 73  ? 182.213 217.084 223.376 1.00 18.13  ? 73  LEU L CD1 1 
ATOM   5741 C CD2 . LEU D 4 73  ? 180.754 216.476 225.332 1.00 16.64  ? 73  LEU L CD2 1 
ATOM   5742 N N   . THR D 4 74  ? 185.531 217.894 225.003 1.00 22.72  ? 74  THR L N   1 
ATOM   5743 C CA  . THR D 4 74  ? 185.993 219.113 225.624 1.00 25.52  ? 74  THR L CA  1 
ATOM   5744 C C   . THR D 4 74  ? 185.002 220.213 225.356 1.00 24.09  ? 74  THR L C   1 
ATOM   5745 O O   . THR D 4 74  ? 184.561 220.421 224.222 1.00 26.20  ? 74  THR L O   1 
ATOM   5746 C CB  . THR D 4 74  ? 187.386 219.538 225.111 1.00 27.10  ? 74  THR L CB  1 
ATOM   5747 O OG1 . THR D 4 74  ? 188.341 218.513 225.408 1.00 27.55  ? 74  THR L OG1 1 
ATOM   5748 C CG2 . THR D 4 74  ? 187.830 220.845 225.805 1.00 28.68  ? 74  THR L CG2 1 
ATOM   5749 N N   . ILE D 4 75  ? 184.629 220.904 226.413 1.00 27.92  ? 75  ILE L N   1 
ATOM   5750 C CA  . ILE D 4 75  ? 183.740 222.043 226.298 1.00 27.89  ? 75  ILE L CA  1 
ATOM   5751 C C   . ILE D 4 75  ? 184.581 223.234 226.718 1.00 31.59  ? 75  ILE L C   1 
ATOM   5752 O O   . ILE D 4 75  ? 185.149 223.222 227.811 1.00 35.18  ? 75  ILE L O   1 
ATOM   5753 C CB  . ILE D 4 75  ? 182.487 221.895 227.168 1.00 28.01  ? 75  ILE L CB  1 
ATOM   5754 C CG1 . ILE D 4 75  ? 181.749 220.605 226.746 1.00 25.07  ? 75  ILE L CG1 1 
ATOM   5755 C CG2 . ILE D 4 75  ? 181.585 223.151 226.979 1.00 29.35  ? 75  ILE L CG2 1 
ATOM   5756 C CD1 . ILE D 4 75  ? 180.636 220.157 227.652 1.00 22.27  ? 75  ILE L CD1 1 
ATOM   5757 N N   . SER D 4 76  ? 184.678 224.254 225.868 1.00 32.69  ? 76  SER L N   1 
ATOM   5758 C CA  . SER D 4 76  ? 185.539 225.400 226.163 1.00 34.08  ? 76  SER L CA  1 
ATOM   5759 C C   . SER D 4 76  ? 184.856 226.529 226.936 1.00 36.76  ? 76  SER L C   1 
ATOM   5760 O O   . SER D 4 76  ? 184.864 226.533 228.162 1.00 38.65  ? 76  SER L O   1 
ATOM   5761 C CB  . SER D 4 76  ? 186.142 225.933 224.874 1.00 34.23  ? 76  SER L CB  1 
ATOM   5762 O OG  . SER D 4 76  ? 185.163 226.466 224.027 1.00 32.69  ? 76  SER L OG  1 
ATOM   5763 N N   . GLY D 4 77  ? 184.256 227.489 226.257 1.00 34.74  ? 77  GLY L N   1 
ATOM   5764 C CA  . GLY D 4 77  ? 183.627 228.627 226.925 1.00 36.32  ? 77  GLY L CA  1 
ATOM   5765 C C   . GLY D 4 77  ? 182.322 228.238 227.594 1.00 36.03  ? 77  GLY L C   1 
ATOM   5766 O O   . GLY D 4 77  ? 181.249 228.617 227.143 1.00 36.57  ? 77  GLY L O   1 
ATOM   5767 N N   . LEU D 4 78  ? 182.437 227.516 228.693 1.00 37.79  ? 78  LEU L N   1 
ATOM   5768 C CA  . LEU D 4 78  ? 181.328 226.926 229.412 1.00 38.08  ? 78  LEU L CA  1 
ATOM   5769 C C   . LEU D 4 78  ? 180.307 227.968 229.788 1.00 37.41  ? 78  LEU L C   1 
ATOM   5770 O O   . LEU D 4 78  ? 180.649 229.046 230.286 1.00 42.33  ? 78  LEU L O   1 
ATOM   5771 C CB  . LEU D 4 78  ? 181.878 226.257 230.681 1.00 38.86  ? 78  LEU L CB  1 
ATOM   5772 C CG  . LEU D 4 78  ? 180.953 225.395 231.542 1.00 39.72  ? 78  LEU L CG  1 
ATOM   5773 C CD1 . LEU D 4 78  ? 180.610 224.123 230.804 1.00 35.54  ? 78  LEU L CD1 1 
ATOM   5774 C CD2 . LEU D 4 78  ? 181.655 225.080 232.843 1.00 44.05  ? 78  LEU L CD2 1 
ATOM   5775 N N   . GLN D 4 79  ? 179.045 227.643 229.507 1.00 35.58  ? 79  GLN L N   1 
ATOM   5776 C CA  . GLN D 4 79  ? 177.900 228.498 229.775 1.00 35.67  ? 79  GLN L CA  1 
ATOM   5777 C C   . GLN D 4 79  ? 176.956 227.825 230.744 1.00 36.80  ? 79  GLN L C   1 
ATOM   5778 O O   . GLN D 4 79  ? 176.929 226.610 230.849 1.00 39.35  ? 79  GLN L O   1 
ATOM   5779 C CB  . GLN D 4 79  ? 177.145 228.828 228.485 1.00 38.58  ? 79  GLN L CB  1 
ATOM   5780 C CG  . GLN D 4 79  ? 177.946 229.611 227.474 1.00 37.04  ? 79  GLN L CG  1 
ATOM   5781 C CD  . GLN D 4 79  ? 177.158 229.949 226.228 1.00 38.56  ? 79  GLN L CD  1 
ATOM   5782 O OE1 . GLN D 4 79  ? 176.265 229.203 225.818 1.00 37.53  ? 79  GLN L OE1 1 
ATOM   5783 N NE2 . GLN D 4 79  ? 177.479 231.078 225.614 1.00 39.23  ? 79  GLN L NE2 1 
ATOM   5784 N N   . ALA D 4 80  ? 176.117 228.598 231.420 1.00 41.29  ? 80  ALA L N   1 
ATOM   5785 C CA  . ALA D 4 80  ? 175.140 228.025 232.357 1.00 42.78  ? 80  ALA L CA  1 
ATOM   5786 C C   . ALA D 4 80  ? 174.211 227.026 231.678 1.00 44.43  ? 80  ALA L C   1 
ATOM   5787 O O   . ALA D 4 80  ? 173.824 226.010 232.262 1.00 44.31  ? 80  ALA L O   1 
ATOM   5788 C CB  . ALA D 4 80  ? 174.312 229.126 232.979 1.00 47.82  ? 80  ALA L CB  1 
ATOM   5789 N N   . ASP D 4 81  ? 173.923 227.259 230.411 1.00 43.37  ? 81  ASP L N   1 
ATOM   5790 C CA  . ASP D 4 81  ? 172.988 226.442 229.670 1.00 43.11  ? 81  ASP L CA  1 
ATOM   5791 C C   . ASP D 4 81  ? 173.585 225.124 229.206 1.00 40.85  ? 81  ASP L C   1 
ATOM   5792 O O   . ASP D 4 81  ? 172.909 224.330 228.558 1.00 37.55  ? 81  ASP L O   1 
ATOM   5793 C CB  . ASP D 4 81  ? 172.479 227.224 228.471 1.00 48.96  ? 81  ASP L CB  1 
ATOM   5794 C CG  . ASP D 4 81  ? 171.618 228.410 228.879 1.00 54.36  ? 81  ASP L CG  1 
ATOM   5795 O OD1 . ASP D 4 81  ? 171.059 228.400 229.950 1.00 52.31  ? 81  ASP L OD1 1 
ATOM   5796 O OD2 . ASP D 4 81  ? 171.554 229.337 228.118 1.00 61.30  ? 81  ASP L OD2 1 
ATOM   5797 N N   . ASP D 4 82  ? 174.838 224.856 229.553 1.00 39.78  ? 82  ASP L N   1 
ATOM   5798 C CA  . ASP D 4 82  ? 175.447 223.598 229.180 1.00 34.17  ? 82  ASP L CA  1 
ATOM   5799 C C   . ASP D 4 82  ? 175.071 222.497 230.160 1.00 31.38  ? 82  ASP L C   1 
ATOM   5800 O O   . ASP D 4 82  ? 175.408 221.334 229.929 1.00 32.25  ? 82  ASP L O   1 
ATOM   5801 C CB  . ASP D 4 82  ? 176.964 223.710 229.126 1.00 34.83  ? 82  ASP L CB  1 
ATOM   5802 C CG  . ASP D 4 82  ? 177.466 224.576 228.000 1.00 34.08  ? 82  ASP L CG  1 
ATOM   5803 O OD1 . ASP D 4 82  ? 176.779 224.763 227.017 1.00 34.94  ? 82  ASP L OD1 1 
ATOM   5804 O OD2 . ASP D 4 82  ? 178.583 225.045 228.122 1.00 32.93  ? 82  ASP L OD2 1 
ATOM   5805 N N   . GLU D 4 83  ? 174.385 222.821 231.266 1.00 35.11  ? 83  GLU L N   1 
ATOM   5806 C CA  . GLU D 4 83  ? 174.037 221.742 232.183 1.00 35.54  ? 83  GLU L CA  1 
ATOM   5807 C C   . GLU D 4 83  ? 173.218 220.686 231.454 1.00 34.51  ? 83  GLU L C   1 
ATOM   5808 O O   . GLU D 4 83  ? 172.156 220.983 230.887 1.00 34.17  ? 83  GLU L O   1 
ATOM   5809 C CB  . GLU D 4 83  ? 173.229 222.286 233.363 1.00 43.95  ? 83  GLU L CB  1 
ATOM   5810 C CG  . GLU D 4 83  ? 172.783 221.225 234.386 1.00 46.21  ? 83  GLU L CG  1 
ATOM   5811 C CD  . GLU D 4 83  ? 172.028 221.793 235.570 1.00 46.72  ? 83  GLU L CD  1 
ATOM   5812 O OE1 . GLU D 4 83  ? 172.063 222.984 235.766 1.00 66.73  ? 83  GLU L OE1 1 
ATOM   5813 O OE2 . GLU D 4 83  ? 171.404 221.029 236.268 1.00 68.08  ? 83  GLU L OE2 1 
ATOM   5814 N N   . ALA D 4 84  ? 173.712 219.451 231.493 1.00 31.42  ? 84  ALA L N   1 
ATOM   5815 C CA  . ALA D 4 84  ? 173.076 218.331 230.797 1.00 27.03  ? 84  ALA L CA  1 
ATOM   5816 C C   . ALA D 4 84  ? 173.735 217.017 231.139 1.00 22.34  ? 84  ALA L C   1 
ATOM   5817 O O   . ALA D 4 84  ? 174.862 216.996 231.635 1.00 32.61  ? 84  ALA L O   1 
ATOM   5818 C CB  . ALA D 4 84  ? 173.123 218.518 229.294 1.00 24.05  ? 84  ALA L CB  1 
ATOM   5819 N N   . ASP D 4 85  ? 173.069 215.921 230.805 1.00 23.65  ? 85  ASP L N   1 
ATOM   5820 C CA  . ASP D 4 85  ? 173.703 214.619 230.882 1.00 21.03  ? 85  ASP L CA  1 
ATOM   5821 C C   . ASP D 4 85  ? 174.372 214.311 229.564 1.00 17.04  ? 85  ASP L C   1 
ATOM   5822 O O   . ASP D 4 85  ? 173.712 214.180 228.532 1.00 21.22  ? 85  ASP L O   1 
ATOM   5823 C CB  . ASP D 4 85  ? 172.693 213.529 231.232 1.00 23.76  ? 85  ASP L CB  1 
ATOM   5824 C CG  . ASP D 4 85  ? 172.263 213.624 232.657 1.00 27.11  ? 85  ASP L CG  1 
ATOM   5825 O OD1 . ASP D 4 85  ? 173.070 214.021 233.433 1.00 31.88  ? 85  ASP L OD1 1 
ATOM   5826 O OD2 . ASP D 4 85  ? 171.148 213.317 232.997 1.00 31.71  ? 85  ASP L OD2 1 
ATOM   5827 N N   . TYR D 4 86  ? 175.686 214.227 229.576 1.00 20.40  ? 86  TYR L N   1 
ATOM   5828 C CA  . TYR D 4 86  ? 176.399 213.957 228.344 1.00 16.36  ? 86  TYR L CA  1 
ATOM   5829 C C   . TYR D 4 86  ? 176.697 212.484 228.250 1.00 16.30  ? 86  TYR L C   1 
ATOM   5830 O O   . TYR D 4 86  ? 177.141 211.872 229.216 1.00 22.86  ? 86  TYR L O   1 
ATOM   5831 C CB  . TYR D 4 86  ? 177.673 214.789 228.276 1.00 16.93  ? 86  TYR L CB  1 
ATOM   5832 C CG  . TYR D 4 86  ? 177.393 216.246 228.081 1.00 17.87  ? 86  TYR L CG  1 
ATOM   5833 C CD1 . TYR D 4 86  ? 177.140 217.031 229.156 1.00 20.76  ? 86  TYR L CD1 1 
ATOM   5834 C CD2 . TYR D 4 86  ? 177.383 216.791 226.821 1.00 17.45  ? 86  TYR L CD2 1 
ATOM   5835 C CE1 . TYR D 4 86  ? 176.864 218.341 228.983 1.00 21.22  ? 86  TYR L CE1 1 
ATOM   5836 C CE2 . TYR D 4 86  ? 177.113 218.116 226.660 1.00 18.87  ? 86  TYR L CE2 1 
ATOM   5837 C CZ  . TYR D 4 86  ? 176.848 218.888 227.751 1.00 21.03  ? 86  TYR L CZ  1 
ATOM   5838 O OH  . TYR D 4 86  ? 176.557 220.227 227.618 1.00 23.65  ? 86  TYR L OH  1 
ATOM   5839 N N   . TYR D 4 87  ? 176.458 211.902 227.090 1.00 15.18  ? 87  TYR L N   1 
ATOM   5840 C CA  . TYR D 4 87  ? 176.706 210.478 226.906 1.00 14.44  ? 87  TYR L CA  1 
ATOM   5841 C C   . TYR D 4 87  ? 177.640 210.234 225.757 1.00 11.86  ? 87  TYR L C   1 
ATOM   5842 O O   . TYR D 4 87  ? 177.507 210.897 224.732 1.00 12.65  ? 87  TYR L O   1 
ATOM   5843 C CB  . TYR D 4 87  ? 175.415 209.741 226.546 1.00 13.85  ? 87  TYR L CB  1 
ATOM   5844 C CG  . TYR D 4 87  ? 174.368 209.785 227.546 1.00 16.54  ? 87  TYR L CG  1 
ATOM   5845 C CD1 . TYR D 4 87  ? 173.461 210.806 227.530 1.00 17.11  ? 87  TYR L CD1 1 
ATOM   5846 C CD2 . TYR D 4 87  ? 174.287 208.814 228.478 1.00 17.22  ? 87  TYR L CD2 1 
ATOM   5847 C CE1 . TYR D 4 87  ? 172.484 210.845 228.457 1.00 16.94  ? 87  TYR L CE1 1 
ATOM   5848 C CE2 . TYR D 4 87  ? 173.304 208.864 229.405 1.00 18.33  ? 87  TYR L CE2 1 
ATOM   5849 C CZ  . TYR D 4 87  ? 172.405 209.878 229.395 1.00 18.01  ? 87  TYR L CZ  1 
ATOM   5850 O OH  . TYR D 4 87  ? 171.409 209.932 230.329 1.00 21.53  ? 87  TYR L OH  1 
ATOM   5851 N N   . CYS D 4 88  ? 178.514 209.221 225.875 1.00 13.98  ? 88  CYS L N   1 
ATOM   5852 C CA  . CYS D 4 88  ? 179.354 208.735 224.793 1.00 12.54  ? 88  CYS L CA  1 
ATOM   5853 C C   . CYS D 4 88  ? 178.798 207.416 224.317 1.00 13.63  ? 88  CYS L C   1 
ATOM   5854 O O   . CYS D 4 88  ? 178.254 206.608 225.092 1.00 16.74  ? 88  CYS L O   1 
ATOM   5855 C CB  . CYS D 4 88  ? 180.837 208.551 225.218 1.00 15.17  ? 88  CYS L CB  1 
ATOM   5856 S SG  . CYS D 4 88  ? 181.201 207.302 226.528 1.00 25.62  ? 88  CYS L SG  1 
ATOM   5857 N N   . SER D 4 89  ? 179.021 207.150 223.054 1.00 12.49  ? 89  SER L N   1 
ATOM   5858 C CA  . SER D 4 89  ? 178.694 205.861 222.506 1.00 11.09  ? 89  SER L CA  1 
ATOM   5859 C C   . SER D 4 89  ? 179.682 205.522 221.457 1.00 10.99  ? 89  SER L C   1 
ATOM   5860 O O   . SER D 4 89  ? 180.347 206.392 220.894 1.00 12.61  ? 89  SER L O   1 
ATOM   5861 C CB  . SER D 4 89  ? 177.329 205.824 221.895 1.00 11.72  ? 89  SER L CB  1 
ATOM   5862 O OG  . SER D 4 89  ? 177.272 206.601 220.772 1.00 12.88  ? 89  SER L OG  1 
ATOM   5863 N N   . ALA D 4 90  ? 179.769 204.254 221.157 1.00 11.63  ? 90  ALA L N   1 
ATOM   5864 C CA  . ALA D 4 90  ? 180.672 203.851 220.118 1.00 10.70  ? 90  ALA L CA  1 
ATOM   5865 C C   . ALA D 4 90  ? 180.176 202.650 219.373 1.00 9.56   ? 90  ALA L C   1 
ATOM   5866 O O   . ALA D 4 90  ? 179.460 201.801 219.914 1.00 11.39  ? 90  ALA L O   1 
ATOM   5867 C CB  . ALA D 4 90  ? 182.035 203.546 220.717 1.00 12.62  ? 90  ALA L CB  1 
ATOM   5868 N N   . TYR D 4 91  ? 180.567 202.591 218.112 1.00 9.29   ? 91  TYR L N   1 
ATOM   5869 C CA  . TYR D 4 91  ? 180.326 201.416 217.306 1.00 8.64   ? 91  TYR L CA  1 
ATOM   5870 C C   . TYR D 4 91  ? 181.300 200.368 217.783 1.00 10.18  ? 91  TYR L C   1 
ATOM   5871 O O   . TYR D 4 91  ? 182.476 200.669 217.963 1.00 12.64  ? 91  TYR L O   1 
ATOM   5872 C CB  . TYR D 4 91  ? 180.501 201.720 215.840 1.00 6.13   ? 91  TYR L CB  1 
ATOM   5873 C CG  . TYR D 4 91  ? 180.346 200.566 214.951 1.00 5.86   ? 91  TYR L CG  1 
ATOM   5874 C CD1 . TYR D 4 91  ? 179.121 199.998 214.715 1.00 5.88   ? 91  TYR L CD1 1 
ATOM   5875 C CD2 . TYR D 4 91  ? 181.452 200.079 214.339 1.00 6.57   ? 91  TYR L CD2 1 
ATOM   5876 C CE1 . TYR D 4 91  ? 179.036 198.939 213.860 1.00 5.45   ? 91  TYR L CE1 1 
ATOM   5877 C CE2 . TYR D 4 91  ? 181.366 199.048 213.499 1.00 6.23   ? 91  TYR L CE2 1 
ATOM   5878 C CZ  . TYR D 4 91  ? 180.178 198.480 213.252 1.00 5.15   ? 91  TYR L CZ  1 
ATOM   5879 O OH  . TYR D 4 91  ? 180.128 197.447 212.396 1.00 6.04   ? 91  TYR L OH  1 
ATOM   5880 N N   . ALA D 4 92  ? 180.824 199.160 218.027 1.00 9.70   ? 92  ALA L N   1 
ATOM   5881 C CA  . ALA D 4 92  ? 181.701 198.129 218.548 1.00 9.90   ? 92  ALA L CA  1 
ATOM   5882 C C   . ALA D 4 92  ? 181.670 196.829 217.759 1.00 10.94  ? 92  ALA L C   1 
ATOM   5883 O O   . ALA D 4 92  ? 181.891 195.759 218.319 1.00 14.64  ? 92  ALA L O   1 
ATOM   5884 C CB  . ALA D 4 92  ? 181.347 197.879 219.996 1.00 13.40  ? 92  ALA L CB  1 
ATOM   5885 N N   . GLY D 4 93  ? 181.439 196.909 216.464 1.00 9.28   ? 93  GLY L N   1 
ATOM   5886 C CA  . GLY D 4 93  ? 181.439 195.724 215.614 1.00 8.75   ? 93  GLY L CA  1 
ATOM   5887 C C   . GLY D 4 93  ? 180.052 195.344 215.131 1.00 9.64   ? 93  GLY L C   1 
ATOM   5888 O O   . GLY D 4 93  ? 179.072 195.978 215.476 1.00 10.38  ? 93  GLY L O   1 
ATOM   5889 N N   . ARG D 4 94  ? 179.960 194.265 214.345 1.00 11.16  ? 94  ARG L N   1 
ATOM   5890 C CA  . ARG D 4 94  ? 178.686 193.854 213.740 1.00 8.90   ? 94  ARG L CA  1 
ATOM   5891 C C   . ARG D 4 94  ? 177.901 192.882 214.605 1.00 12.26  ? 94  ARG L C   1 
ATOM   5892 O O   . ARG D 4 94  ? 176.871 192.358 214.186 1.00 13.04  ? 94  ARG L O   1 
ATOM   5893 C CB  . ARG D 4 94  ? 178.905 193.182 212.392 1.00 3.84   ? 94  ARG L CB  1 
ATOM   5894 C CG  . ARG D 4 94  ? 179.632 194.005 211.323 1.00 7.48   ? 94  ARG L CG  1 
ATOM   5895 C CD  . ARG D 4 94  ? 178.845 195.192 210.762 1.00 0.02   ? 94  ARG L CD  1 
ATOM   5896 N NE  . ARG D 4 94  ? 177.678 194.814 209.971 1.00 0.09   ? 94  ARG L NE  1 
ATOM   5897 C CZ  . ARG D 4 94  ? 176.837 195.689 209.379 1.00 0.21   ? 94  ARG L CZ  1 
ATOM   5898 N NH1 . ARG D 4 94  ? 177.043 196.978 209.461 1.00 0.03   ? 94  ARG L NH1 1 
ATOM   5899 N NH2 . ARG D 4 94  ? 175.808 195.242 208.715 1.00 2.97   ? 94  ARG L NH2 1 
ATOM   5900 N N   . GLN D 4 95  ? 178.444 192.544 215.765 1.00 14.87  ? 95  GLN L N   1 
ATOM   5901 C CA  . GLN D 4 95  ? 177.773 191.632 216.679 1.00 15.24  ? 95  GLN L CA  1 
ATOM   5902 C C   . GLN D 4 95  ? 177.087 192.391 217.798 1.00 15.67  ? 95  GLN L C   1 
ATOM   5903 O O   . GLN D 4 95  ? 175.976 192.056 218.195 1.00 18.13  ? 95  GLN L O   1 
ATOM   5904 C CB  . GLN D 4 95  ? 178.777 190.660 217.270 1.00 19.55  ? 95  GLN L CB  1 
ATOM   5905 C CG  . GLN D 4 95  ? 179.304 189.630 216.302 1.00 20.99  ? 95  GLN L CG  1 
ATOM   5906 C CD  . GLN D 4 95  ? 180.254 190.214 215.280 1.00 19.94  ? 95  GLN L CD  1 
ATOM   5907 O OE1 . GLN D 4 95  ? 180.868 191.276 215.498 1.00 18.98  ? 95  GLN L OE1 1 
ATOM   5908 N NE2 . GLN D 4 95  ? 180.389 189.526 214.152 1.00 20.58  ? 95  GLN L NE2 1 
ATOM   5909 N N   . THR D 4 96  A 177.741 193.435 218.272 1.00 15.10  ? 95  THR L N   1 
ATOM   5910 C CA  . THR D 4 96  A 177.269 194.289 219.344 1.00 13.96  ? 95  THR L CA  1 
ATOM   5911 C C   . THR D 4 96  A 177.392 195.690 218.824 1.00 12.68  ? 95  THR L C   1 
ATOM   5912 O O   . THR D 4 96  A 178.333 196.403 219.157 1.00 17.37  ? 95  THR L O   1 
ATOM   5913 C CB  . THR D 4 96  A 178.114 194.139 220.614 1.00 17.30  ? 95  THR L CB  1 
ATOM   5914 O OG1 . THR D 4 96  A 179.477 194.418 220.312 1.00 16.87  ? 95  THR L OG1 1 
ATOM   5915 C CG2 . THR D 4 96  A 178.014 192.725 221.132 1.00 22.84  ? 95  THR L CG2 1 
ATOM   5916 N N   . PHE D 4 97  B 176.439 196.084 218.008 1.00 10.89  ? 95  PHE L N   1 
ATOM   5917 C CA  . PHE D 4 97  B 176.560 197.318 217.264 1.00 7.64   ? 95  PHE L CA  1 
ATOM   5918 C C   . PHE D 4 97  B 176.841 198.548 218.076 1.00 7.83   ? 95  PHE L C   1 
ATOM   5919 O O   . PHE D 4 97  B 177.853 199.204 217.842 1.00 10.18  ? 95  PHE L O   1 
ATOM   5920 C CB  . PHE D 4 97  B 175.281 197.546 216.489 1.00 6.73   ? 95  PHE L CB  1 
ATOM   5921 C CG  . PHE D 4 97  B 175.195 196.835 215.239 1.00 6.78   ? 95  PHE L CG  1 
ATOM   5922 C CD1 . PHE D 4 97  B 174.922 195.509 215.177 1.00 7.38   ? 95  PHE L CD1 1 
ATOM   5923 C CD2 . PHE D 4 97  B 175.369 197.528 214.079 1.00 6.27   ? 95  PHE L CD2 1 
ATOM   5924 C CE1 . PHE D 4 97  B 174.855 194.898 213.983 1.00 6.49   ? 95  PHE L CE1 1 
ATOM   5925 C CE2 . PHE D 4 97  B 175.289 196.919 212.885 1.00 5.26   ? 95  PHE L CE2 1 
ATOM   5926 C CZ  . PHE D 4 97  B 175.038 195.602 212.835 1.00 4.82   ? 95  PHE L CZ  1 
ATOM   5927 N N   . TYR D 4 98  ? 176.015 198.879 219.050 1.00 8.65   ? 96  TYR L N   1 
ATOM   5928 C CA  . TYR D 4 98  ? 176.323 200.099 219.770 1.00 8.05   ? 96  TYR L CA  1 
ATOM   5929 C C   . TYR D 4 98  ? 176.321 199.922 221.231 1.00 10.75  ? 96  TYR L C   1 
ATOM   5930 O O   . TYR D 4 98  ? 175.488 199.216 221.801 1.00 14.79  ? 96  TYR L O   1 
ATOM   5931 C CB  . TYR D 4 98  ? 175.364 201.232 219.418 1.00 7.46   ? 96  TYR L CB  1 
ATOM   5932 C CG  . TYR D 4 98  ? 175.454 201.602 218.018 1.00 7.02   ? 96  TYR L CG  1 
ATOM   5933 C CD1 . TYR D 4 98  ? 176.429 202.456 217.615 1.00 6.73   ? 96  TYR L CD1 1 
ATOM   5934 C CD2 . TYR D 4 98  ? 174.606 201.045 217.116 1.00 6.55   ? 96  TYR L CD2 1 
ATOM   5935 C CE1 . TYR D 4 98  ? 176.566 202.729 216.316 1.00 5.20   ? 96  TYR L CE1 1 
ATOM   5936 C CE2 . TYR D 4 98  ? 174.747 201.327 215.811 1.00 5.73   ? 96  TYR L CE2 1 
ATOM   5937 C CZ  . TYR D 4 98  ? 175.737 202.158 215.428 1.00 4.73   ? 96  TYR L CZ  1 
ATOM   5938 O OH  . TYR D 4 98  ? 175.923 202.404 214.157 1.00 5.13   ? 96  TYR L OH  1 
ATOM   5939 N N   . ILE D 4 99  ? 177.256 200.599 221.850 1.00 11.79  ? 97  ILE L N   1 
ATOM   5940 C CA  . ILE D 4 99  ? 177.312 200.617 223.282 1.00 13.02  ? 97  ILE L CA  1 
ATOM   5941 C C   . ILE D 4 99  ? 177.380 202.046 223.769 1.00 12.11  ? 97  ILE L C   1 
ATOM   5942 O O   . ILE D 4 99  ? 177.911 202.912 223.084 1.00 15.28  ? 97  ILE L O   1 
ATOM   5943 C CB  . ILE D 4 99  ? 178.482 199.771 223.765 1.00 14.38  ? 97  ILE L CB  1 
ATOM   5944 C CG1 . ILE D 4 99  ? 179.768 200.325 223.247 1.00 15.56  ? 97  ILE L CG1 1 
ATOM   5945 C CG2 . ILE D 4 99  ? 178.284 198.306 223.324 1.00 15.90  ? 97  ILE L CG2 1 
ATOM   5946 C CD1 . ILE D 4 99  ? 180.969 199.702 223.816 1.00 16.82  ? 97  ILE L CD1 1 
ATOM   5947 N N   . PHE D 4 100 ? 176.872 202.281 224.964 1.00 13.97  ? 98  PHE L N   1 
ATOM   5948 C CA  . PHE D 4 100 ? 176.856 203.599 225.591 1.00 14.61  ? 98  PHE L CA  1 
ATOM   5949 C C   . PHE D 4 100 ? 177.448 203.596 226.983 1.00 18.81  ? 98  PHE L C   1 
ATOM   5950 O O   . PHE D 4 100 ? 177.494 202.560 227.655 1.00 21.30  ? 98  PHE L O   1 
ATOM   5951 C CB  . PHE D 4 100 ? 175.432 204.160 225.729 1.00 14.45  ? 98  PHE L CB  1 
ATOM   5952 C CG  . PHE D 4 100 ? 174.643 204.536 224.478 1.00 13.07  ? 98  PHE L CG  1 
ATOM   5953 C CD1 . PHE D 4 100 ? 173.948 203.611 223.747 1.00 12.34  ? 98  PHE L CD1 1 
ATOM   5954 C CD2 . PHE D 4 100 ? 174.550 205.859 224.096 1.00 12.50  ? 98  PHE L CD2 1 
ATOM   5955 C CE1 . PHE D 4 100 ? 173.205 203.993 222.657 1.00 11.12  ? 98  PHE L CE1 1 
ATOM   5956 C CE2 . PHE D 4 100 ? 173.808 206.238 223.005 1.00 10.33  ? 98  PHE L CE2 1 
ATOM   5957 C CZ  . PHE D 4 100 ? 173.139 205.303 222.289 1.00 10.20  ? 98  PHE L CZ  1 
ATOM   5958 N N   . GLY D 4 101 ? 177.910 204.756 227.418 1.00 18.02  ? 99  GLY L N   1 
ATOM   5959 C CA  . GLY D 4 101 ? 178.335 204.922 228.800 1.00 20.78  ? 99  GLY L CA  1 
ATOM   5960 C C   . GLY D 4 101 ? 177.165 205.430 229.640 1.00 21.95  ? 99  GLY L C   1 
ATOM   5961 O O   . GLY D 4 101 ? 176.040 205.545 229.153 1.00 21.05  ? 99  GLY L O   1 
ATOM   5962 N N   . GLY D 4 102 ? 177.394 205.722 230.914 1.00 24.00  ? 100 GLY L N   1 
ATOM   5963 C CA  . GLY D 4 102 ? 176.310 206.252 231.727 1.00 23.68  ? 100 GLY L CA  1 
ATOM   5964 C C   . GLY D 4 102 ? 176.340 207.725 231.447 1.00 23.01  ? 100 GLY L C   1 
ATOM   5965 O O   . GLY D 4 102 ? 177.172 208.152 230.670 1.00 22.86  ? 100 GLY L O   1 
ATOM   5966 N N   . GLY D 4 103 ? 175.476 208.522 232.036 1.00 23.58  ? 101 GLY L N   1 
ATOM   5967 C CA  . GLY D 4 103 ? 175.572 209.934 231.696 1.00 22.17  ? 101 GLY L CA  1 
ATOM   5968 C C   . GLY D 4 103 ? 176.481 210.691 232.631 1.00 23.68  ? 101 GLY L C   1 
ATOM   5969 O O   . GLY D 4 103 ? 176.586 210.364 233.815 1.00 26.31  ? 101 GLY L O   1 
ATOM   5970 N N   . THR D 4 104 ? 177.042 211.775 232.129 1.00 24.44  ? 102 THR L N   1 
ATOM   5971 C CA  . THR D 4 104 ? 177.821 212.666 232.954 1.00 24.94  ? 102 THR L CA  1 
ATOM   5972 C C   . THR D 4 104 ? 177.012 213.901 233.247 1.00 26.02  ? 102 THR L C   1 
ATOM   5973 O O   . THR D 4 104 ? 176.789 214.732 232.361 1.00 26.39  ? 102 THR L O   1 
ATOM   5974 C CB  . THR D 4 104 ? 179.108 213.130 232.251 1.00 24.21  ? 102 THR L CB  1 
ATOM   5975 O OG1 . THR D 4 104 ? 179.937 212.014 231.960 1.00 24.63  ? 102 THR L OG1 1 
ATOM   5976 C CG2 . THR D 4 104 ? 179.865 214.136 233.094 1.00 29.76  ? 102 THR L CG2 1 
ATOM   5977 N N   . ARG D 4 105 ? 176.655 214.102 234.499 1.00 29.64  ? 103 ARG L N   1 
ATOM   5978 C CA  . ARG D 4 105 ? 175.854 215.266 234.827 1.00 29.93  ? 103 ARG L CA  1 
ATOM   5979 C C   . ARG D 4 105 ? 176.727 216.483 234.967 1.00 31.60  ? 103 ARG L C   1 
ATOM   5980 O O   . ARG D 4 105 ? 177.214 216.795 236.054 1.00 36.70  ? 103 ARG L O   1 
ATOM   5981 C CB  . ARG D 4 105 ? 175.066 215.042 236.115 1.00 34.07  ? 103 ARG L CB  1 
ATOM   5982 C CG  . ARG D 4 105 ? 174.241 216.258 236.665 1.00 37.18  ? 103 ARG L CG  1 
ATOM   5983 C CD  . ARG D 4 105 ? 173.131 216.680 235.777 1.00 38.62  ? 103 ARG L CD  1 
ATOM   5984 N NE  . ARG D 4 105 ? 172.177 215.617 235.542 1.00 38.42  ? 103 ARG L NE  1 
ATOM   5985 C CZ  . ARG D 4 105 ? 171.110 215.281 236.294 1.00 42.22  ? 103 ARG L CZ  1 
ATOM   5986 N NH1 . ARG D 4 105 ? 170.810 215.938 237.406 1.00 49.95  ? 103 ARG L NH1 1 
ATOM   5987 N NH2 . ARG D 4 105 ? 170.359 214.268 235.882 1.00 44.63  ? 103 ARG L NH2 1 
ATOM   5988 N N   . LEU D 4 106 ? 176.899 217.187 233.862 1.00 29.88  ? 104 LEU L N   1 
ATOM   5989 C CA  . LEU D 4 106 ? 177.745 218.361 233.864 1.00 28.98  ? 104 LEU L CA  1 
ATOM   5990 C C   . LEU D 4 106 ? 177.040 219.469 234.557 1.00 36.04  ? 104 LEU L C   1 
ATOM   5991 O O   . LEU D 4 106 ? 175.937 219.846 234.153 1.00 34.24  ? 104 LEU L O   1 
ATOM   5992 C CB  . LEU D 4 106 ? 178.073 218.841 232.453 1.00 30.47  ? 104 LEU L CB  1 
ATOM   5993 C CG  . LEU D 4 106 ? 178.908 220.172 232.323 1.00 30.67  ? 104 LEU L CG  1 
ATOM   5994 C CD1 . LEU D 4 106 ? 180.279 220.013 232.898 1.00 33.62  ? 104 LEU L CD1 1 
ATOM   5995 C CD2 . LEU D 4 106 ? 178.985 220.532 230.871 1.00 27.58  ? 104 LEU L CD2 1 
ATOM   5996 N N   . THR D 4 107 ? 177.718 220.031 235.548 1.00 36.78  ? 105 THR L N   1 
ATOM   5997 C CA  . THR D 4 107 ? 177.213 221.130 236.354 1.00 40.66  ? 105 THR L CA  1 
ATOM   5998 C C   . THR D 4 107 ? 178.065 222.368 236.172 1.00 42.21  ? 105 THR L C   1 
ATOM   5999 O O   . THR D 4 107 ? 179.298 222.314 236.267 1.00 42.12  ? 105 THR L O   1 
ATOM   6000 C CB  . THR D 4 107 ? 177.165 220.755 237.849 1.00 40.31  ? 105 THR L CB  1 
ATOM   6001 O OG1 . THR D 4 107 ? 176.282 219.643 238.032 1.00 35.78  ? 105 THR L OG1 1 
ATOM   6002 C CG2 . THR D 4 107 ? 176.665 221.932 238.677 1.00 44.33  ? 105 THR L CG2 1 
ATOM   6003 N N   . VAL D 4 108 ? 177.400 223.478 235.911 1.00 44.72  ? 106 VAL L N   1 
ATOM   6004 C CA  . VAL D 4 108 ? 178.092 224.729 235.712 1.00 46.14  ? 106 VAL L CA  1 
ATOM   6005 C C   . VAL D 4 108 ? 177.907 225.550 236.999 1.00 43.27  ? 106 VAL L C   1 
ATOM   6006 O O   . VAL D 4 108 ? 176.769 225.740 237.438 1.00 47.88  ? 106 VAL L O   1 
ATOM   6007 C CB  . VAL D 4 108 ? 177.536 225.421 234.471 1.00 46.70  ? 106 VAL L CB  1 
ATOM   6008 C CG1 . VAL D 4 108 ? 178.284 226.733 234.235 1.00 42.51  ? 106 VAL L CG1 1 
ATOM   6009 C CG2 . VAL D 4 108 ? 177.650 224.447 233.300 1.00 41.99  ? 106 VAL L CG2 1 
ATOM   6010 N N   . LEU D 4 109 ? 179.034 225.959 237.611 1.00 51.45  ? 107 LEU L N   1 
ATOM   6011 C CA  . LEU D 4 109 ? 179.164 226.633 238.918 1.00 48.90  ? 107 LEU L CA  1 
ATOM   6012 C C   . LEU D 4 109 ? 179.276 228.172 238.798 1.00 53.69  ? 107 LEU L C   1 
ATOM   6013 O O   . LEU D 4 109 ? 180.371 228.752 238.863 1.00 54.87  ? 107 LEU L O   1 
ATOM   6014 C CB  . LEU D 4 109 ? 180.412 226.019 239.655 1.00 51.16  ? 107 LEU L CB  1 
ATOM   6015 C CG  . LEU D 4 109 ? 180.420 224.386 239.899 1.00 51.35  ? 107 LEU L CG  1 
ATOM   6016 C CD1 . LEU D 4 109 ? 181.802 223.952 240.504 1.00 49.62  ? 107 LEU L CD1 1 
ATOM   6017 C CD2 . LEU D 4 109 ? 179.218 223.955 240.839 1.00 52.96  ? 107 LEU L CD2 1 
HETATM 6018 C C1  . NAG E 5 .   ? 169.192 221.322 128.916 1.00 24.01  ? 1   NAG C C1  1 
HETATM 6019 C C2  . NAG E 5 .   ? 170.604 220.830 128.336 1.00 24.63  ? 1   NAG C C2  1 
HETATM 6020 C C3  . NAG E 5 .   ? 171.525 222.100 128.235 1.00 27.56  ? 1   NAG C C3  1 
HETATM 6021 C C4  . NAG E 5 .   ? 170.870 223.193 127.318 1.00 30.59  ? 1   NAG C C4  1 
HETATM 6022 C C5  . NAG E 5 .   ? 169.447 223.549 127.878 1.00 28.34  ? 1   NAG C C5  1 
HETATM 6023 C C6  . NAG E 5 .   ? 168.657 224.472 126.953 1.00 30.63  ? 1   NAG C C6  1 
HETATM 6024 C C7  . NAG E 5 .   ? 171.249 218.519 129.045 1.00 23.34  ? 1   NAG C C7  1 
HETATM 6025 C C8  . NAG E 5 .   ? 171.879 217.609 130.059 1.00 20.77  ? 1   NAG C C8  1 
HETATM 6026 N N2  . NAG E 5 .   ? 171.209 219.842 129.273 1.00 24.43  ? 1   NAG C N2  1 
HETATM 6027 O O3  . NAG E 5 .   ? 172.804 221.727 127.684 1.00 30.23  ? 1   NAG C O3  1 
HETATM 6028 O O4  . NAG E 5 .   ? 171.665 224.413 127.465 1.00 37.07  ? 1   NAG C O4  1 
HETATM 6029 O O5  . NAG E 5 .   ? 168.623 222.329 128.012 1.00 25.52  ? 1   NAG C O5  1 
HETATM 6030 O O6  . NAG E 5 .   ? 167.438 224.911 127.544 1.00 31.36  ? 1   NAG C O6  1 
HETATM 6031 O O7  . NAG E 5 .   ? 170.782 218.028 128.007 1.00 27.00  ? 1   NAG C O7  1 
HETATM 6032 C C1  . NAG E 5 .   ? 172.457 224.884 126.267 1.00 40.94  ? 2   NAG C C1  1 
HETATM 6033 C C2  . NAG E 5 .   ? 172.636 226.454 126.391 1.00 42.53  ? 2   NAG C C2  1 
HETATM 6034 C C3  . NAG E 5 .   ? 173.483 226.950 125.165 1.00 49.89  ? 2   NAG C C3  1 
HETATM 6035 C C4  . NAG E 5 .   ? 174.863 226.199 125.125 1.00 51.49  ? 2   NAG C C4  1 
HETATM 6036 C C5  . NAG E 5 .   ? 174.595 224.648 125.017 1.00 49.62  ? 2   NAG C C5  1 
HETATM 6037 C C6  . NAG E 5 .   ? 175.885 223.814 125.037 1.00 51.17  ? 2   NAG C C6  1 
HETATM 6038 C C7  . NAG E 5 .   ? 170.820 227.933 127.279 1.00 43.69  ? 2   NAG C C7  1 
HETATM 6039 C C8  . NAG E 5 .   ? 169.438 228.509 127.142 1.00 44.95  ? 2   NAG C C8  1 
HETATM 6040 N N2  . NAG E 5 .   ? 171.286 227.089 126.345 1.00 43.98  ? 2   NAG C N2  1 
HETATM 6041 O O3  . NAG E 5 .   ? 173.719 228.367 125.293 1.00 48.39  ? 2   NAG C O3  1 
HETATM 6042 O O4  . NAG E 5 .   ? 175.616 226.650 123.993 1.00 54.22  ? 2   NAG C O4  1 
HETATM 6043 O O5  . NAG E 5 .   ? 173.755 224.213 126.178 1.00 45.58  ? 2   NAG C O5  1 
HETATM 6044 O O6  . NAG E 5 .   ? 175.685 222.515 124.483 1.00 51.02  ? 2   NAG C O6  1 
HETATM 6045 O O7  . NAG E 5 .   ? 171.506 228.257 128.262 1.00 41.53  ? 2   NAG C O7  1 
HETATM 6046 C C1  . NAG F 5 .   ? 152.532 218.282 131.372 1.00 29.13  ? 1   NAG D C1  1 
HETATM 6047 C C2  . NAG F 5 .   ? 151.417 217.171 131.227 1.00 30.29  ? 1   NAG D C2  1 
HETATM 6048 C C3  . NAG F 5 .   ? 150.947 217.129 129.737 1.00 32.36  ? 1   NAG D C3  1 
HETATM 6049 C C4  . NAG F 5 .   ? 150.397 218.554 129.331 1.00 38.15  ? 1   NAG D C4  1 
HETATM 6050 C C5  . NAG F 5 .   ? 151.538 219.620 129.550 1.00 34.45  ? 1   NAG D C5  1 
HETATM 6051 C C6  . NAG F 5 .   ? 151.109 221.066 129.298 1.00 38.14  ? 1   NAG D C6  1 
HETATM 6052 C C7  . NAG F 5 .   ? 152.222 214.659 132.041 1.00 25.26  ? 1   NAG D C7  1 
HETATM 6053 C C8  . NAG F 5 .   ? 153.495 214.268 132.737 1.00 20.88  ? 1   NAG D C8  1 
HETATM 6054 N N2  . NAG F 5 .   ? 152.012 215.923 131.725 1.00 26.73  ? 1   NAG D N2  1 
HETATM 6055 O O3  . NAG F 5 .   ? 149.903 216.141 129.623 1.00 36.74  ? 1   NAG D O3  1 
HETATM 6056 O O4  . NAG F 5 .   ? 150.059 218.559 127.913 1.00 43.53  ? 1   NAG D O4  1 
HETATM 6057 O O5  . NAG F 5 .   ? 151.991 219.582 130.960 1.00 30.05  ? 1   NAG D O5  1 
HETATM 6058 O O6  . NAG F 5 .   ? 152.237 221.922 129.110 1.00 36.15  ? 1   NAG D O6  1 
HETATM 6059 O O7  . NAG F 5 .   ? 151.367 213.810 131.769 1.00 31.33  ? 1   NAG D O7  1 
HETATM 6060 C C1  . NAG F 5 .   ? 148.587 218.590 127.559 1.00 46.20  ? 2   NAG D C1  1 
HETATM 6061 C C2  . NAG F 5 .   ? 148.450 219.111 126.071 1.00 48.55  ? 2   NAG D C2  1 
HETATM 6062 C C3  . NAG F 5 .   ? 146.922 219.128 125.700 1.00 53.81  ? 2   NAG D C3  1 
HETATM 6063 C C4  . NAG F 5 .   ? 146.314 217.689 125.875 1.00 56.68  ? 2   NAG D C4  1 
HETATM 6064 C C5  . NAG F 5 .   ? 146.512 217.229 127.369 1.00 53.82  ? 2   NAG D C5  1 
HETATM 6065 C C6  . NAG F 5 .   ? 146.035 215.791 127.614 1.00 56.33  ? 2   NAG D C6  1 
HETATM 6066 C C7  . NAG F 5 .   ? 150.130 220.807 125.325 1.00 45.45  ? 2   NAG D C7  1 
HETATM 6067 C C8  . NAG F 5 .   ? 150.611 222.231 125.299 1.00 49.92  ? 2   NAG D C8  1 
HETATM 6068 N N2  . NAG F 5 .   ? 149.001 220.496 125.985 1.00 51.02  ? 2   NAG D N2  1 
HETATM 6069 O O3  . NAG F 5 .   ? 146.767 219.547 124.329 1.00 52.05  ? 2   NAG D O3  1 
HETATM 6070 O O4  . NAG F 5 .   ? 144.921 217.718 125.549 1.00 55.77  ? 2   NAG D O4  1 
HETATM 6071 O O5  . NAG F 5 .   ? 147.965 217.277 127.706 1.00 48.48  ? 2   NAG D O5  1 
HETATM 6072 O O6  . NAG F 5 .   ? 145.892 215.507 129.005 1.00 58.55  ? 2   NAG D O6  1 
HETATM 6073 O O7  . NAG F 5 .   ? 150.793 219.942 124.730 1.00 47.01  ? 2   NAG D O7  1 
HETATM 6074 C C1  . NAG G 6 .   ? 157.569 206.897 144.381 1.00 17.96  ? 1   NAG E C1  1 
HETATM 6075 C C2  . NAG G 6 .   ? 158.063 205.936 143.203 1.00 18.72  ? 1   NAG E C2  1 
HETATM 6076 C C3  . NAG G 6 .   ? 156.838 205.649 142.260 1.00 19.45  ? 1   NAG E C3  1 
HETATM 6077 C C4  . NAG G 6 .   ? 155.681 204.992 143.090 1.00 22.50  ? 1   NAG E C4  1 
HETATM 6078 C C5  . NAG G 6 .   ? 155.271 205.967 144.238 1.00 21.07  ? 1   NAG E C5  1 
HETATM 6079 C C6  . NAG G 6 .   ? 154.205 205.406 145.180 1.00 23.63  ? 1   NAG E C6  1 
HETATM 6080 C C7  . NAG G 6 .   ? 160.407 206.176 142.372 1.00 13.34  ? 1   NAG E C7  1 
HETATM 6081 C C8  . NAG G 6 .   ? 161.436 206.898 141.557 1.00 12.53  ? 1   NAG E C8  1 
HETATM 6082 N N2  . NAG G 6 .   ? 159.142 206.613 142.422 1.00 16.56  ? 1   NAG E N2  1 
HETATM 6083 O O3  . NAG G 6 .   ? 157.231 204.747 141.205 1.00 22.31  ? 1   NAG E O3  1 
HETATM 6084 O O4  . NAG G 6 .   ? 154.522 204.795 142.233 1.00 27.81  ? 1   NAG E O4  1 
HETATM 6085 O O5  . NAG G 6 .   ? 156.447 206.264 145.075 1.00 20.44  ? 1   NAG E O5  1 
HETATM 6086 O O6  . NAG G 6 .   ? 154.543 204.134 145.727 1.00 23.95  ? 1   NAG E O6  1 
HETATM 6087 O O7  . NAG G 6 .   ? 160.753 205.164 142.994 1.00 16.82  ? 1   NAG E O7  1 
HETATM 6088 C C1  . NAG G 6 .   ? 154.099 203.365 142.023 1.00 30.20  ? 2   NAG E C1  1 
HETATM 6089 C C2  . NAG G 6 .   ? 152.583 203.328 141.586 1.00 32.38  ? 2   NAG E C2  1 
HETATM 6090 C C3  . NAG G 6 .   ? 152.181 201.819 141.399 1.00 36.75  ? 2   NAG E C3  1 
HETATM 6091 C C4  . NAG G 6 .   ? 153.112 201.138 140.327 1.00 35.40  ? 2   NAG E C4  1 
HETATM 6092 C C5  . NAG G 6 .   ? 154.610 201.277 140.806 1.00 35.32  ? 2   NAG E C5  1 
HETATM 6093 C C6  . NAG G 6 .   ? 155.625 200.760 139.778 1.00 34.96  ? 2   NAG E C6  1 
HETATM 6094 C C7  . NAG G 6 .   ? 151.014 205.055 142.483 1.00 32.66  ? 2   NAG E C7  1 
HETATM 6095 C C8  . NAG G 6 .   ? 150.227 205.618 143.632 1.00 34.54  ? 2   NAG E C8  1 
HETATM 6096 N N2  . NAG G 6 .   ? 151.760 203.953 142.661 1.00 32.91  ? 2   NAG E N2  1 
HETATM 6097 O O3  . NAG G 6 .   ? 150.810 201.777 140.963 1.00 37.25  ? 2   NAG E O3  1 
HETATM 6098 O O4  . NAG G 6 .   ? 152.790 199.716 140.275 1.00 44.96  ? 2   NAG E O4  1 
HETATM 6099 O O5  . NAG G 6 .   ? 154.942 202.707 141.037 1.00 31.91  ? 2   NAG E O5  1 
HETATM 6100 O O6  . NAG G 6 .   ? 155.634 201.517 138.567 1.00 31.46  ? 2   NAG E O6  1 
HETATM 6101 O O7  . NAG G 6 .   ? 150.954 205.631 141.384 1.00 32.02  ? 2   NAG E O7  1 
HETATM 6102 C C1  . BMA G 6 .   ? 152.298 199.195 138.947 1.00 44.71  ? 3   BMA E C1  1 
HETATM 6103 C C2  . BMA G 6 .   ? 152.335 197.645 138.965 1.00 51.30  ? 3   BMA E C2  1 
HETATM 6104 C C3  . BMA G 6 .   ? 151.945 197.146 137.577 1.00 63.65  ? 3   BMA E C3  1 
HETATM 6105 C C4  . BMA G 6 .   ? 150.541 197.685 137.287 1.00 57.05  ? 3   BMA E C4  1 
HETATM 6106 C C5  . BMA G 6 .   ? 150.576 199.213 137.316 1.00 54.56  ? 3   BMA E C5  1 
HETATM 6107 C C6  . BMA G 6 .   ? 149.214 199.790 137.019 1.00 48.70  ? 3   BMA E C6  1 
HETATM 6108 O O2  . BMA G 6 .   ? 151.422 197.134 139.925 1.00 56.36  ? 3   BMA E O2  1 
HETATM 6109 O O3  . BMA G 6 .   ? 151.936 195.685 137.575 1.00 52.78  ? 3   BMA E O3  1 
HETATM 6110 O O4  . BMA G 6 .   ? 150.094 197.241 136.017 1.00 61.36  ? 3   BMA E O4  1 
HETATM 6111 O O5  . BMA G 6 .   ? 150.992 199.680 138.623 1.00 56.98  ? 3   BMA E O5  1 
HETATM 6112 O O6  . BMA G 6 .   ? 148.205 199.083 137.721 1.00 51.78  ? 3   BMA E O6  1 
HETATM 6113 C C1  . MAN G 6 .   ? 152.732 195.028 136.465 1.00 49.06  ? 4   MAN E C1  1 
HETATM 6114 C C2  . MAN G 6 .   ? 152.387 193.489 136.398 1.00 55.38  ? 4   MAN E C2  1 
HETATM 6115 C C3  . MAN G 6 .   ? 152.969 192.797 137.680 1.00 63.23  ? 4   MAN E C3  1 
HETATM 6116 C C4  . MAN G 6 .   ? 154.517 193.043 137.767 1.00 60.47  ? 4   MAN E C4  1 
HETATM 6117 C C5  . MAN G 6 .   ? 154.781 194.597 137.810 1.00 55.61  ? 4   MAN E C5  1 
HETATM 6118 C C6  . MAN G 6 .   ? 156.276 194.941 137.809 1.00 54.13  ? 4   MAN E C6  1 
HETATM 6119 O O2  . MAN G 6 .   ? 152.899 192.914 135.188 1.00 60.97  ? 4   MAN E O2  1 
HETATM 6120 O O3  . MAN G 6 .   ? 152.688 191.385 137.632 1.00 64.74  ? 4   MAN E O3  1 
HETATM 6121 O O4  . MAN G 6 .   ? 155.031 192.426 138.950 1.00 65.20  ? 4   MAN E O4  1 
HETATM 6122 O O5  . MAN G 6 .   ? 154.179 195.234 136.601 1.00 57.94  ? 4   MAN E O5  1 
HETATM 6123 O O6  . MAN G 6 .   ? 156.516 196.312 138.126 1.00 51.88  ? 4   MAN E O6  1 
HETATM 6124 C C1  . NAG H 5 .   ? 161.380 198.952 110.172 1.00 30.62  ? 1   NAG F C1  1 
HETATM 6125 C C2  . NAG H 5 .   ? 159.868 199.422 110.339 1.00 30.68  ? 1   NAG F C2  1 
HETATM 6126 C C3  . NAG H 5 .   ? 158.947 198.238 109.878 1.00 33.20  ? 1   NAG F C3  1 
HETATM 6127 C C4  . NAG H 5 .   ? 159.267 197.806 108.403 1.00 36.67  ? 1   NAG F C4  1 
HETATM 6128 C C5  . NAG H 5 .   ? 160.788 197.407 108.328 1.00 34.03  ? 1   NAG F C5  1 
HETATM 6129 C C6  . NAG H 5 .   ? 161.282 197.036 106.931 1.00 36.25  ? 1   NAG F C6  1 
HETATM 6130 C C7  . NAG H 5 .   ? 159.016 200.764 112.274 1.00 28.60  ? 1   NAG F C7  1 
HETATM 6131 C C8  . NAG H 5 .   ? 158.808 200.929 113.746 1.00 27.25  ? 1   NAG F C8  1 
HETATM 6132 N N2  . NAG H 5 .   ? 159.637 199.679 111.789 1.00 29.56  ? 1   NAG F N2  1 
HETATM 6133 O O3  . NAG H 5 .   ? 157.575 198.663 109.963 1.00 34.47  ? 1   NAG F O3  1 
HETATM 6134 O O4  . NAG H 5 .   ? 158.457 196.627 108.134 1.00 40.22  ? 1   NAG F O4  1 
HETATM 6135 O O5  . NAG H 5 .   ? 161.623 198.547 108.783 1.00 32.36  ? 1   NAG F O5  1 
HETATM 6136 O O6  . NAG H 5 .   ? 162.673 196.726 106.918 1.00 34.40  ? 1   NAG F O6  1 
HETATM 6137 O O7  . NAG H 5 .   ? 158.590 201.652 111.534 1.00 32.35  ? 1   NAG F O7  1 
HETATM 6138 C C1  . NAG H 5 .   ? 157.767 196.548 106.791 1.00 44.22  ? 2   NAG F C1  1 
HETATM 6139 C C2  . NAG H 5 .   ? 157.395 195.029 106.542 1.00 44.72  ? 2   NAG F C2  1 
HETATM 6140 C C3  . NAG H 5 .   ? 156.699 194.923 105.139 1.00 47.26  ? 2   NAG F C3  1 
HETATM 6141 C C4  . NAG H 5 .   ? 155.432 195.853 105.100 1.00 50.22  ? 2   NAG F C4  1 
HETATM 6142 C C5  . NAG H 5 .   ? 155.882 197.336 105.389 1.00 50.50  ? 2   NAG F C5  1 
HETATM 6143 C C6  . NAG H 5 .   ? 154.712 198.321 105.448 1.00 52.47  ? 2   NAG F C6  1 
HETATM 6144 C C7  . NAG H 5 .   ? 158.956 193.324 107.507 1.00 40.88  ? 2   NAG F C7  1 
HETATM 6145 C C8  . NAG H 5 .   ? 160.261 192.585 107.439 1.00 40.82  ? 2   NAG F C8  1 
HETATM 6146 N N2  . NAG H 5 .   ? 158.657 194.229 106.557 1.00 41.80  ? 2   NAG F N2  1 
HETATM 6147 O O3  . NAG H 5 .   ? 156.294 193.559 104.910 1.00 46.26  ? 2   NAG F O3  1 
HETATM 6148 O O4  . NAG H 5 .   ? 154.815 195.767 103.811 1.00 49.38  ? 2   NAG F O4  1 
HETATM 6149 O O5  . NAG H 5 .   ? 156.575 197.391 106.711 1.00 45.17  ? 2   NAG F O5  1 
HETATM 6150 O O6  . NAG H 5 .   ? 155.162 199.675 105.458 1.00 52.77  ? 2   NAG F O6  1 
HETATM 6151 O O7  . NAG H 5 .   ? 158.177 193.085 108.446 1.00 41.42  ? 2   NAG F O7  1 
HETATM 6152 C C1  . NAG I 7 .   ? 181.550 215.414 199.123 1.00 28.43  ? 1   NAG G C1  1 
HETATM 6153 C C2  . NAG I 7 .   ? 181.489 216.012 200.601 1.00 32.70  ? 1   NAG G C2  1 
HETATM 6154 C C3  . NAG I 7 .   ? 180.597 217.303 200.585 1.00 36.85  ? 1   NAG G C3  1 
HETATM 6155 C C4  . NAG I 7 .   ? 181.184 218.346 199.575 1.00 38.01  ? 1   NAG G C4  1 
HETATM 6156 C C5  . NAG I 7 .   ? 181.249 217.687 198.154 1.00 33.84  ? 1   NAG G C5  1 
HETATM 6157 C C6  . NAG I 7 .   ? 181.882 218.590 197.090 1.00 38.03  ? 1   NAG G C6  1 
HETATM 6158 C C7  . NAG I 7 .   ? 181.501 214.444 202.548 1.00 33.59  ? 1   NAG G C7  1 
HETATM 6159 C C8  . NAG I 7 .   ? 180.797 213.442 203.423 1.00 34.70  ? 1   NAG G C8  1 
HETATM 6160 N N2  . NAG I 7 .   ? 180.862 215.009 201.508 1.00 32.18  ? 1   NAG G N2  1 
HETATM 6161 O O3  . NAG I 7 .   ? 180.574 217.885 201.904 1.00 36.88  ? 1   NAG G O3  1 
HETATM 6162 O O4  . NAG I 7 .   ? 180.329 219.495 199.538 1.00 37.90  ? 1   NAG G O4  1 
HETATM 6163 O O5  . NAG I 7 .   ? 182.064 216.449 198.219 1.00 30.64  ? 1   NAG G O5  1 
HETATM 6164 O O6  . NAG I 7 .   ? 183.251 218.936 197.419 1.00 42.81  ? 1   NAG G O6  1 
HETATM 6165 O O7  . NAG I 7 .   ? 182.674 214.735 202.823 1.00 35.16  ? 1   NAG G O7  1 
HETATM 6166 C C1  . FUC I 7 .   ? 183.815 220.097 196.631 1.00 48.06  ? 2   FUC G C1  1 
HETATM 6167 C C2  . FUC I 7 .   ? 185.352 220.289 196.958 1.00 52.56  ? 2   FUC G C2  1 
HETATM 6168 C C3  . FUC I 7 .   ? 186.141 219.067 196.377 1.00 52.79  ? 2   FUC G C3  1 
HETATM 6169 C C4  . FUC I 7 .   ? 185.897 218.963 194.827 1.00 47.17  ? 2   FUC G C4  1 
HETATM 6170 C C5  . FUC I 7 .   ? 184.346 218.808 194.580 1.00 43.58  ? 2   FUC G C5  1 
HETATM 6171 C C6  . FUC I 7 .   ? 183.959 218.765 193.107 1.00 40.54  ? 2   FUC G C6  1 
HETATM 6172 O O2  . FUC I 7 .   ? 185.564 220.396 198.370 1.00 51.79  ? 2   FUC G O2  1 
HETATM 6173 O O3  . FUC I 7 .   ? 187.552 219.236 196.643 1.00 53.40  ? 2   FUC G O3  1 
HETATM 6174 O O4  . FUC I 7 .   ? 186.462 220.093 194.148 1.00 51.17  ? 2   FUC G O4  1 
HETATM 6175 O O5  . FUC I 7 .   ? 183.613 219.957 195.186 1.00 47.42  ? 2   FUC G O5  1 
HETATM 6176 C C1  . NAG J 7 .   ? 198.652 205.126 194.032 1.00 30.00  ? 1   NAG I C1  1 
HETATM 6177 C C2  . NAG J 7 .   ? 199.610 204.148 194.693 1.00 30.00  ? 1   NAG I C2  1 
HETATM 6178 C C3  . NAG J 7 .   ? 200.844 204.941 195.082 1.00 30.00  ? 1   NAG I C3  1 
HETATM 6179 C C4  . NAG J 7 .   ? 201.430 205.508 193.811 1.00 30.00  ? 1   NAG I C4  1 
HETATM 6180 C C5  . NAG J 7 .   ? 200.399 206.425 193.195 1.00 30.00  ? 1   NAG I C5  1 
HETATM 6181 C C6  . NAG J 7 .   ? 200.936 207.041 191.931 1.00 30.00  ? 1   NAG I C6  1 
HETATM 6182 C C7  . NAG J 7 .   ? 199.195 202.323 196.235 1.00 30.00  ? 1   NAG I C7  1 
HETATM 6183 C C8  . NAG J 7 .   ? 199.323 201.315 195.134 1.00 30.00  ? 1   NAG I C8  1 
HETATM 6184 N N2  . NAG J 7 .   ? 199.002 203.585 195.874 1.00 30.00  ? 1   NAG I N2  1 
HETATM 6185 O O3  . NAG J 7 .   ? 201.836 204.128 195.710 1.00 30.00  ? 1   NAG I O3  1 
HETATM 6186 O O4  . NAG J 7 .   ? 202.647 206.214 194.077 1.00 30.00  ? 1   NAG I O4  1 
HETATM 6187 O O5  . NAG J 7 .   ? 199.263 205.654 192.869 1.00 30.00  ? 1   NAG I O5  1 
HETATM 6188 O O6  . NAG J 7 .   ? 200.972 205.986 190.973 1.00 30.00  ? 1   NAG I O6  1 
HETATM 6189 O O7  . NAG J 7 .   ? 199.272 202.003 197.404 1.00 30.00  ? 1   NAG I O7  1 
HETATM 6190 C C1  . FUC J 7 .   ? 201.231 206.586 189.702 1.00 30.00  ? 2   FUC I C1  1 
HETATM 6191 C C2  . FUC J 7 .   ? 201.620 205.527 188.689 1.00 30.00  ? 2   FUC I C2  1 
HETATM 6192 C C3  . FUC J 7 .   ? 200.415 204.695 188.302 1.00 30.00  ? 2   FUC I C3  1 
HETATM 6193 C C4  . FUC J 7 .   ? 199.276 205.590 187.829 1.00 30.00  ? 2   FUC I C4  1 
HETATM 6194 C C5  . FUC J 7 .   ? 198.977 206.649 188.881 1.00 30.00  ? 2   FUC I C5  1 
HETATM 6195 C C6  . FUC J 7 .   ? 197.953 207.652 188.390 1.00 30.00  ? 2   FUC I C6  1 
HETATM 6196 O O2  . FUC J 7 .   ? 202.581 204.663 189.288 1.00 30.00  ? 2   FUC I O2  1 
HETATM 6197 O O3  . FUC J 7 .   ? 200.803 203.786 187.267 1.00 30.00  ? 2   FUC I O3  1 
HETATM 6198 O O4  . FUC J 7 .   ? 199.631 206.204 186.588 1.00 30.00  ? 2   FUC I O4  1 
HETATM 6199 O O5  . FUC J 7 .   ? 200.151 207.379 189.228 1.00 30.00  ? 2   FUC I O5  1 
HETATM 6200 C C1  . NAG K 8 .   ? 166.689 213.071 184.323 1.00 21.43  ? 601 NAG A C1  1 
HETATM 6201 C C2  . NAG K 8 .   ? 166.311 211.783 185.163 1.00 21.39  ? 601 NAG A C2  1 
HETATM 6202 C C3  . NAG K 8 .   ? 165.012 212.088 185.984 1.00 23.74  ? 601 NAG A C3  1 
HETATM 6203 C C4  . NAG K 8 .   ? 165.274 213.322 186.922 1.00 27.00  ? 601 NAG A C4  1 
HETATM 6204 C C5  . NAG K 8 .   ? 165.701 214.559 186.048 1.00 26.94  ? 601 NAG A C5  1 
HETATM 6205 C C6  . NAG K 8 .   ? 166.084 215.778 186.887 1.00 32.39  ? 601 NAG A C6  1 
HETATM 6206 C C7  . NAG K 8 .   ? 166.643 209.435 184.393 1.00 16.21  ? 601 NAG A C7  1 
HETATM 6207 C C8  . NAG K 8 .   ? 166.468 208.349 183.371 1.00 13.20  ? 601 NAG A C8  1 
HETATM 6208 N N2  . NAG K 8 .   ? 166.138 210.660 184.195 1.00 20.03  ? 601 NAG A N2  1 
HETATM 6209 O O3  . NAG K 8 .   ? 164.666 210.944 186.787 1.00 24.05  ? 601 NAG A O3  1 
HETATM 6210 O O4  . NAG K 8 .   ? 164.082 213.630 187.648 1.00 30.05  ? 601 NAG A O4  1 
HETATM 6211 O O5  . NAG K 8 .   ? 166.900 214.206 185.239 1.00 24.20  ? 601 NAG A O5  1 
HETATM 6212 O O6  . NAG K 8 .   ? 166.329 216.924 186.074 1.00 36.04  ? 601 NAG A O6  1 
HETATM 6213 O O7  . NAG K 8 .   ? 167.265 209.174 185.425 1.00 19.89  ? 601 NAG A O7  1 
HETATM 6214 C C1  . NAG L 8 .   ? 172.230 189.611 107.330 1.00 29.53  ? 602 NAG A C1  1 
HETATM 6215 C C2  . NAG L 8 .   ? 173.138 190.885 107.043 1.00 31.71  ? 602 NAG A C2  1 
HETATM 6216 C C3  . NAG L 8 .   ? 172.945 191.312 105.544 1.00 35.42  ? 602 NAG A C3  1 
HETATM 6217 C C4  . NAG L 8 .   ? 173.327 190.111 104.604 1.00 37.55  ? 602 NAG A C4  1 
HETATM 6218 C C5  . NAG L 8 .   ? 172.425 188.875 104.959 1.00 35.64  ? 602 NAG A C5  1 
HETATM 6219 C C6  . NAG L 8 .   ? 172.784 187.618 104.167 1.00 39.80  ? 602 NAG A C6  1 
HETATM 6220 C C7  . NAG L 8 .   ? 173.583 192.685 108.721 1.00 28.49  ? 602 NAG A C7  1 
HETATM 6221 C C8  . NAG L 8 .   ? 173.103 193.747 109.662 1.00 23.29  ? 602 NAG A C8  1 
HETATM 6222 N N2  . NAG L 8 .   ? 172.713 191.966 107.984 1.00 29.29  ? 602 NAG A N2  1 
HETATM 6223 O O3  . NAG L 8 .   ? 173.805 192.431 105.247 1.00 35.78  ? 602 NAG A O3  1 
HETATM 6224 O O4  . NAG L 8 .   ? 173.121 190.484 103.239 1.00 39.98  ? 602 NAG A O4  1 
HETATM 6225 O O5  . NAG L 8 .   ? 172.601 188.538 106.396 1.00 32.64  ? 602 NAG A O5  1 
HETATM 6226 O O6  . NAG L 8 .   ? 171.830 186.581 104.387 1.00 41.63  ? 602 NAG A O6  1 
HETATM 6227 O O7  . NAG L 8 .   ? 174.804 192.488 108.645 1.00 29.11  ? 602 NAG A O7  1 
HETATM 6228 C C1  . NAG M 8 .   ? 175.791 221.847 161.781 1.00 24.67  ? 603 NAG A C1  1 
HETATM 6229 C C2  . NAG M 8 .   ? 176.504 223.098 161.090 1.00 27.17  ? 603 NAG A C2  1 
HETATM 6230 C C3  . NAG M 8 .   ? 177.913 223.280 161.760 1.00 29.40  ? 603 NAG A C3  1 
HETATM 6231 C C4  . NAG M 8 .   ? 177.753 223.482 163.309 1.00 30.07  ? 603 NAG A C4  1 
HETATM 6232 C C5  . NAG M 8 .   ? 177.002 222.245 163.912 1.00 27.44  ? 603 NAG A C5  1 
HETATM 6233 C C6  . NAG M 8 .   ? 176.725 222.351 165.412 1.00 26.87  ? 603 NAG A C6  1 
HETATM 6234 C C7  . NAG M 8 .   ? 175.726 223.168 158.705 1.00 25.01  ? 603 NAG A C7  1 
HETATM 6235 C C8  . NAG M 8 .   ? 175.917 222.900 157.237 1.00 21.15  ? 603 NAG A C8  1 
HETATM 6236 N N2  . NAG M 8 .   ? 176.668 222.846 159.621 1.00 27.12  ? 603 NAG A N2  1 
HETATM 6237 O O3  . NAG M 8 .   ? 178.562 224.437 161.196 1.00 31.61  ? 603 NAG A O3  1 
HETATM 6238 O O4  . NAG M 8 .   ? 179.047 223.592 163.905 1.00 31.98  ? 603 NAG A O4  1 
HETATM 6239 O O5  . NAG M 8 .   ? 175.689 222.084 163.232 1.00 26.09  ? 603 NAG A O5  1 
HETATM 6240 O O6  . NAG M 8 .   ? 175.896 223.460 165.747 1.00 30.97  ? 603 NAG A O6  1 
HETATM 6241 O O7  . NAG M 8 .   ? 174.667 223.707 159.054 1.00 25.29  ? 603 NAG A O7  1 
HETATM 6242 C C1  . NAG N 8 .   ? 151.357 211.498 109.461 1.00 106.40 ? 604 NAG A C1  1 
HETATM 6243 C C2  . NAG N 8 .   ? 149.860 210.951 109.432 1.00 103.71 ? 604 NAG A C2  1 
HETATM 6244 C C3  . NAG N 8 .   ? 149.264 211.213 107.996 1.00 101.65 ? 604 NAG A C3  1 
HETATM 6245 C C4  . NAG N 8 .   ? 149.320 212.751 107.672 1.00 102.51 ? 604 NAG A C4  1 
HETATM 6246 C C5  . NAG N 8 .   ? 150.810 213.242 107.761 1.00 127.14 ? 604 NAG A C5  1 
HETATM 6247 C C6  . NAG N 8 .   ? 150.971 214.751 107.534 1.00 98.38  ? 604 NAG A C6  1 
HETATM 6248 C C7  . NAG N 8 .   ? 148.945 208.860 110.448 1.00 109.66 ? 604 NAG A C7  1 
HETATM 6249 C C8  . NAG N 8 .   ? 149.073 207.388 110.719 1.00 106.49 ? 604 NAG A C8  1 
HETATM 6250 N N2  . NAG N 8 .   ? 149.900 209.493 109.743 1.00 100.28 ? 604 NAG A N2  1 
HETATM 6251 O O3  . NAG N 8 .   ? 147.892 210.769 107.940 1.00 92.65  ? 604 NAG A O3  1 
HETATM 6252 O O4  . NAG N 8 .   ? 148.814 212.977 106.352 1.00 80.87  ? 604 NAG A O4  1 
HETATM 6253 O O5  . NAG N 8 .   ? 151.352 212.934 109.117 1.00 142.72 ? 604 NAG A O5  1 
HETATM 6254 O O6  . NAG N 8 .   ? 150.240 215.541 108.472 1.00 102.43 ? 604 NAG A O6  1 
HETATM 6255 O O7  . NAG N 8 .   ? 147.955 209.469 110.889 1.00 112.32 ? 604 NAG A O7  1 
HETATM 6256 C C1  . NAG O 8 .   ? 168.765 237.860 158.352 1.00 56.02  ? 605 NAG A C1  1 
HETATM 6257 C C2  . NAG O 8 .   ? 169.005 238.299 159.866 1.00 60.99  ? 605 NAG A C2  1 
HETATM 6258 C C3  . NAG O 8 .   ? 167.877 237.658 160.751 1.00 60.38  ? 605 NAG A C3  1 
HETATM 6259 C C4  . NAG O 8 .   ? 166.472 238.132 160.240 1.00 56.57  ? 605 NAG A C4  1 
HETATM 6260 C C5  . NAG O 8 .   ? 166.304 237.724 158.730 1.00 56.79  ? 605 NAG A C5  1 
HETATM 6261 C C6  . NAG O 8 .   ? 164.989 238.226 158.120 1.00 58.46  ? 605 NAG A C6  1 
HETATM 6262 C C7  . NAG O 8 .   ? 171.422 238.618 160.409 1.00 55.70  ? 605 NAG A C7  1 
HETATM 6263 C C8  . NAG O 8 .   ? 172.741 238.044 160.842 1.00 58.78  ? 605 NAG A C8  1 
HETATM 6264 N N2  . NAG O 8 .   ? 170.348 237.814 160.297 1.00 58.58  ? 605 NAG A N2  1 
HETATM 6265 O O3  . NAG O 8 .   ? 168.053 238.066 162.123 1.00 60.97  ? 605 NAG A O3  1 
HETATM 6266 O O4  . NAG O 8 .   ? 165.450 237.513 161.027 1.00 63.89  ? 605 NAG A O4  1 
HETATM 6267 O O5  . NAG O 8 .   ? 167.422 238.310 157.927 1.00 55.57  ? 605 NAG A O5  1 
HETATM 6268 O O6  . NAG O 8 .   ? 164.748 237.649 156.839 1.00 56.79  ? 605 NAG A O6  1 
HETATM 6269 O O7  . NAG O 8 .   ? 171.355 239.833 160.157 1.00 56.25  ? 605 NAG A O7  1 
HETATM 6270 C C1  . NAG P 8 .   ? 186.513 223.778 155.900 1.00 36.83  ? 606 NAG A C1  1 
HETATM 6271 C C2  . NAG P 8 .   ? 187.875 223.328 156.590 1.00 40.20  ? 606 NAG A C2  1 
HETATM 6272 C C3  . NAG P 8 .   ? 188.799 224.595 156.719 1.00 42.29  ? 606 NAG A C3  1 
HETATM 6273 C C4  . NAG P 8 .   ? 189.048 225.227 155.304 1.00 41.50  ? 606 NAG A C4  1 
HETATM 6274 C C5  . NAG P 8 .   ? 187.666 225.609 154.667 1.00 39.28  ? 606 NAG A C5  1 
HETATM 6275 C C6  . NAG P 8 .   ? 187.760 226.122 153.231 1.00 36.07  ? 606 NAG A C6  1 
HETATM 6276 C C7  . NAG P 8 .   ? 187.677 221.510 158.285 1.00 40.37  ? 606 NAG A C7  1 
HETATM 6277 C C8  . NAG P 8 .   ? 187.324 221.076 159.679 1.00 42.73  ? 606 NAG A C8  1 
HETATM 6278 N N2  . NAG P 8 .   ? 187.557 222.800 157.946 1.00 41.70  ? 606 NAG A N2  1 
HETATM 6279 O O3  . NAG P 8 .   ? 190.062 224.203 157.291 1.00 42.57  ? 606 NAG A O3  1 
HETATM 6280 O O4  . NAG P 8 .   ? 189.858 226.398 155.436 1.00 43.40  ? 606 NAG A O4  1 
HETATM 6281 O O5  . NAG P 8 .   ? 186.817 224.398 154.608 1.00 36.40  ? 606 NAG A O5  1 
HETATM 6282 O O6  . NAG P 8 .   ? 186.520 226.691 152.811 1.00 34.26  ? 606 NAG A O6  1 
HETATM 6283 O O7  . NAG P 8 .   ? 188.081 220.659 157.478 1.00 39.41  ? 606 NAG A O7  1 
HETATM 6284 C C1  . NAG Q 8 .   ? 166.461 230.980 131.867 1.00 48.04  ? 607 NAG A C1  1 
HETATM 6285 C C2  . NAG Q 8 .   ? 166.605 230.165 130.498 1.00 48.48  ? 607 NAG A C2  1 
HETATM 6286 C C3  . NAG Q 8 .   ? 166.741 231.189 129.318 1.00 51.95  ? 607 NAG A C3  1 
HETATM 6287 C C4  . NAG Q 8 .   ? 165.482 232.127 129.289 1.00 56.89  ? 607 NAG A C4  1 
HETATM 6288 C C5  . NAG Q 8 .   ? 165.360 232.871 130.667 1.00 56.18  ? 607 NAG A C5  1 
HETATM 6289 C C6  . NAG Q 8 .   ? 164.093 233.725 130.776 1.00 58.04  ? 607 NAG A C6  1 
HETATM 6290 C C7  . NAG Q 8 .   ? 167.765 227.941 130.460 1.00 40.27  ? 607 NAG A C7  1 
HETATM 6291 C C8  . NAG Q 8 .   ? 169.022 227.120 130.567 1.00 36.93  ? 607 NAG A C8  1 
HETATM 6292 N N2  . NAG Q 8 .   ? 167.816 229.285 130.576 1.00 45.93  ? 607 NAG A N2  1 
HETATM 6293 O O3  . NAG Q 8 .   ? 166.830 230.475 128.068 1.00 53.39  ? 607 NAG A O3  1 
HETATM 6294 O O4  . NAG Q 8 .   ? 165.624 233.085 128.234 1.00 56.36  ? 607 NAG A O4  1 
HETATM 6295 O O5  . NAG Q 8 .   ? 165.288 231.869 131.766 1.00 50.03  ? 607 NAG A O5  1 
HETATM 6296 O O6  . NAG Q 8 .   ? 164.054 234.461 131.996 1.00 60.40  ? 607 NAG A O6  1 
HETATM 6297 O O7  . NAG Q 8 .   ? 166.683 227.360 130.268 1.00 37.25  ? 607 NAG A O7  1 
HETATM 6298 C C1  . NAG R 8 .   ? 159.215 233.461 142.567 1.00 42.07  ? 608 NAG A C1  1 
HETATM 6299 C C2  . NAG R 8 .   ? 158.142 234.197 141.643 1.00 47.01  ? 608 NAG A C2  1 
HETATM 6300 C C3  . NAG R 8 .   ? 158.720 235.594 141.224 1.00 49.83  ? 608 NAG A C3  1 
HETATM 6301 C C4  . NAG R 8 .   ? 159.033 236.440 142.509 1.00 51.46  ? 608 NAG A C4  1 
HETATM 6302 C C5  . NAG R 8 .   ? 160.053 235.651 143.412 1.00 46.44  ? 608 NAG A C5  1 
HETATM 6303 C C6  . NAG R 8 .   ? 160.369 236.372 144.729 1.00 45.09  ? 608 NAG A C6  1 
HETATM 6304 C C7  . NAG R 8 .   ? 156.782 232.573 140.317 1.00 45.58  ? 608 NAG A C7  1 
HETATM 6305 C C8  . NAG R 8 .   ? 156.595 231.724 139.098 1.00 45.52  ? 608 NAG A C8  1 
HETATM 6306 N N2  . NAG R 8 .   ? 157.882 233.345 140.445 1.00 46.82  ? 608 NAG A N2  1 
HETATM 6307 O O3  . NAG R 8 .   ? 157.748 236.289 140.416 1.00 51.69  ? 608 NAG A O3  1 
HETATM 6308 O O4  . NAG R 8 .   ? 159.603 237.694 142.119 1.00 51.26  ? 608 NAG A O4  1 
HETATM 6309 O O5  . NAG R 8 .   ? 159.491 234.305 143.749 1.00 43.62  ? 608 NAG A O5  1 
HETATM 6310 O O6  . NAG R 8 .   ? 159.229 236.513 145.575 1.00 48.92  ? 608 NAG A O6  1 
HETATM 6311 O O7  . NAG R 8 .   ? 155.906 232.541 141.200 1.00 46.83  ? 608 NAG A O7  1 
HETATM 6312 C C1  . NAG S 8 .   ? 150.115 215.205 138.818 1.00 29.92  ? 609 NAG A C1  1 
HETATM 6313 C C2  . NAG S 8 .   ? 149.636 216.710 138.645 1.00 30.02  ? 609 NAG A C2  1 
HETATM 6314 C C3  . NAG S 8 .   ? 148.567 217.007 139.755 1.00 32.63  ? 609 NAG A C3  1 
HETATM 6315 C C4  . NAG S 8 .   ? 147.373 215.986 139.643 1.00 35.68  ? 609 NAG A C4  1 
HETATM 6316 C C5  . NAG S 8 .   ? 147.940 214.527 139.786 1.00 33.66  ? 609 NAG A C5  1 
HETATM 6317 C C6  . NAG S 8 .   ? 146.897 213.424 139.613 1.00 38.39  ? 609 NAG A C6  1 
HETATM 6318 C C7  . NAG S 8 .   ? 151.397 218.302 137.827 1.00 26.75  ? 609 NAG A C7  1 
HETATM 6319 C C8  . NAG S 8 .   ? 152.615 219.142 138.097 1.00 23.70  ? 609 NAG A C8  1 
HETATM 6320 N N2  . NAG S 8 .   ? 150.840 217.586 138.820 1.00 27.95  ? 609 NAG A N2  1 
HETATM 6321 O O3  . NAG S 8 .   ? 148.066 218.345 139.576 1.00 32.80  ? 609 NAG A O3  1 
HETATM 6322 O O4  . NAG S 8 .   ? 146.424 216.238 140.681 1.00 37.23  ? 609 NAG A O4  1 
HETATM 6323 O O5  . NAG S 8 .   ? 148.962 214.299 138.739 1.00 31.30  ? 609 NAG A O5  1 
HETATM 6324 O O6  . NAG S 8 .   ? 147.487 212.123 139.722 1.00 38.83  ? 609 NAG A O6  1 
HETATM 6325 O O7  . NAG S 8 .   ? 150.916 218.276 136.684 1.00 27.63  ? 609 NAG A O7  1 
HETATM 6326 C C1  . NAG T 8 .   ? 153.838 212.507 149.005 1.00 31.67  ? 610 NAG A C1  1 
HETATM 6327 C C2  . NAG T 8 .   ? 153.396 210.985 148.855 1.00 32.46  ? 610 NAG A C2  1 
HETATM 6328 C C3  . NAG T 8 .   ? 151.921 210.832 149.363 1.00 35.84  ? 610 NAG A C3  1 
HETATM 6329 C C4  . NAG T 8 .   ? 151.831 211.297 150.857 1.00 40.10  ? 610 NAG A C4  1 
HETATM 6330 C C5  . NAG T 8 .   ? 152.314 212.788 150.957 1.00 39.57  ? 610 NAG A C5  1 
HETATM 6331 C C6  . NAG T 8 .   ? 152.358 213.312 152.394 1.00 43.02  ? 610 NAG A C6  1 
HETATM 6332 C C7  . NAG T 8 .   ? 154.203 209.575 146.964 1.00 25.25  ? 610 NAG A C7  1 
HETATM 6333 C C8  . NAG T 8 .   ? 154.273 209.309 145.489 1.00 21.87  ? 610 NAG A C8  1 
HETATM 6334 N N2  . NAG T 8 .   ? 153.503 210.627 147.414 1.00 28.92  ? 610 NAG A N2  1 
HETATM 6335 O O3  . NAG T 8 .   ? 151.525 209.449 149.272 1.00 36.09  ? 610 NAG A O3  1 
HETATM 6336 O O4  . NAG T 8 .   ? 150.476 211.197 151.304 1.00 44.18  ? 610 NAG A O4  1 
HETATM 6337 O O5  . NAG T 8 .   ? 153.696 212.902 150.417 1.00 34.36  ? 610 NAG A O5  1 
HETATM 6338 O O6  . NAG T 8 .   ? 153.218 212.548 153.238 1.00 45.41  ? 610 NAG A O6  1 
HETATM 6339 O O7  . NAG T 8 .   ? 154.797 208.821 147.757 1.00 24.71  ? 610 NAG A O7  1 
HETATM 6340 C C1  . NAG U 8 .   ? 147.969 200.623 123.142 1.00 44.95  ? 611 NAG A C1  1 
HETATM 6341 C C2  . NAG U 8 .   ? 146.552 201.327 123.311 1.00 47.24  ? 611 NAG A C2  1 
HETATM 6342 C C3  . NAG U 8 .   ? 145.554 200.285 123.929 1.00 48.99  ? 611 NAG A C3  1 
HETATM 6343 C C4  . NAG U 8 .   ? 145.466 199.014 123.012 1.00 50.76  ? 611 NAG A C4  1 
HETATM 6344 C C5  . NAG U 8 .   ? 146.900 198.390 122.868 1.00 48.11  ? 611 NAG A C5  1 
HETATM 6345 C C6  . NAG U 8 .   ? 146.951 197.172 121.940 1.00 50.62  ? 611 NAG A C6  1 
HETATM 6346 C C7  . NAG U 8 .   ? 146.912 203.750 123.840 1.00 41.96  ? 611 NAG A C7  1 
HETATM 6347 C C8  . NAG U 8 .   ? 147.075 204.855 124.848 1.00 42.31  ? 611 NAG A C8  1 
HETATM 6348 N N2  . NAG U 8 .   ? 146.711 202.482 124.248 1.00 45.55  ? 611 NAG A N2  1 
HETATM 6349 O O3  . NAG U 8 .   ? 144.248 200.887 124.038 1.00 50.60  ? 611 NAG A O3  1 
HETATM 6350 O O4  . NAG U 8 .   ? 144.576 198.060 123.599 1.00 52.20  ? 611 NAG A O4  1 
HETATM 6351 O O5  . NAG U 8 .   ? 147.827 199.414 122.304 1.00 46.42  ? 611 NAG A O5  1 
HETATM 6352 O O6  . NAG U 8 .   ? 148.106 196.373 122.188 1.00 48.80  ? 611 NAG A O6  1 
HETATM 6353 O O7  . NAG U 8 .   ? 146.963 204.039 122.634 1.00 44.76  ? 611 NAG A O7  1 
HETATM 6354 C C1  . NAG V 8 .   ? 184.588 202.180 122.762 1.00 33.40  ? 612 NAG A C1  1 
HETATM 6355 C C2  . NAG V 8 .   ? 185.798 202.636 123.690 1.00 34.51  ? 612 NAG A C2  1 
HETATM 6356 C C3  . NAG V 8 .   ? 185.505 204.089 124.202 1.00 35.92  ? 612 NAG A C3  1 
HETATM 6357 C C4  . NAG V 8 .   ? 185.333 205.057 122.979 1.00 37.91  ? 612 NAG A C4  1 
HETATM 6358 C C5  . NAG V 8 .   ? 184.163 204.537 122.067 1.00 35.61  ? 612 NAG A C5  1 
HETATM 6359 C C6  . NAG V 8 .   ? 183.975 205.359 120.790 1.00 37.69  ? 612 NAG A C6  1 
HETATM 6360 C C7  . NAG V 8 .   ? 187.026 200.988 125.104 1.00 32.73  ? 612 NAG A C7  1 
HETATM 6361 C C8  . NAG V 8 .   ? 187.044 200.031 126.261 1.00 33.08  ? 612 NAG A C8  1 
HETATM 6362 N N2  . NAG V 8 .   ? 185.906 201.679 124.825 1.00 33.19  ? 612 NAG A N2  1 
HETATM 6363 O O3  . NAG V 8 .   ? 186.604 204.540 125.017 1.00 37.76  ? 612 NAG A O3  1 
HETATM 6364 O O4  . NAG V 8 .   ? 185.036 206.374 123.448 1.00 38.97  ? 612 NAG A O4  1 
HETATM 6365 O O5  . NAG V 8 .   ? 184.467 203.139 121.646 1.00 34.19  ? 612 NAG A O5  1 
HETATM 6366 O O6  . NAG V 8 .   ? 182.779 204.999 120.100 1.00 33.72  ? 612 NAG A O6  1 
HETATM 6367 O O7  . NAG V 8 .   ? 188.052 201.122 124.418 1.00 34.59  ? 612 NAG A O7  1 
HETATM 6368 C C1  . NAG W 8 .   ? 167.664 210.778 109.182 1.00 41.98  ? 613 NAG A C1  1 
HETATM 6369 C C2  . NAG W 8 .   ? 167.675 211.754 107.921 1.00 46.30  ? 613 NAG A C2  1 
HETATM 6370 C C3  . NAG W 8 .   ? 168.896 212.733 108.066 1.00 48.58  ? 613 NAG A C3  1 
HETATM 6371 C C4  . NAG W 8 .   ? 168.786 213.534 109.411 1.00 48.39  ? 613 NAG A C4  1 
HETATM 6372 C C5  . NAG W 8 .   ? 168.744 212.518 110.611 1.00 46.83  ? 613 NAG A C5  1 
HETATM 6373 C C6  . NAG W 8 .   ? 168.562 213.183 111.985 1.00 42.81  ? 613 NAG A C6  1 
HETATM 6374 C C7  . NAG W 8 .   ? 166.808 210.583 105.891 1.00 43.93  ? 613 NAG A C7  1 
HETATM 6375 C C8  . NAG W 8 .   ? 167.067 209.745 104.671 1.00 47.88  ? 613 NAG A C8  1 
HETATM 6376 N N2  . NAG W 8 .   ? 167.833 210.932 106.687 1.00 44.71  ? 613 NAG A N2  1 
HETATM 6377 O O3  . NAG W 8 .   ? 168.901 213.658 106.961 1.00 45.01  ? 613 NAG A O3  1 
HETATM 6378 O O4  . NAG W 8 .   ? 169.917 214.400 109.545 1.00 48.71  ? 613 NAG A O4  1 
HETATM 6379 O O5  . NAG W 8 .   ? 167.597 211.582 110.417 1.00 42.83  ? 613 NAG A O5  1 
HETATM 6380 O O6  . NAG W 8 .   ? 169.177 212.419 113.022 1.00 39.69  ? 613 NAG A O6  1 
HETATM 6381 O O7  . NAG W 8 .   ? 165.644 210.937 106.140 1.00 42.11  ? 613 NAG A O7  1 
HETATM 6382 C C1  . NAG X 8 .   ? 176.084 215.315 193.794 1.00 30.00  ? 701 NAG B C1  1 
HETATM 6383 C C2  . NAG X 8 .   ? 175.035 214.644 194.675 1.00 30.00  ? 701 NAG B C2  1 
HETATM 6384 C C3  . NAG X 8 .   ? 174.823 215.290 196.033 1.00 30.00  ? 701 NAG B C3  1 
HETATM 6385 C C4  . NAG X 8 .   ? 176.135 215.582 196.731 1.00 30.00  ? 701 NAG B C4  1 
HETATM 6386 C C5  . NAG X 8 .   ? 177.152 216.233 195.807 1.00 30.00  ? 701 NAG B C5  1 
HETATM 6387 C C6  . NAG X 8 .   ? 178.517 216.203 196.463 1.00 30.00  ? 701 NAG B C6  1 
HETATM 6388 C C7  . NAG X 8 .   ? 172.814 215.524 193.931 1.00 30.00  ? 701 NAG B C7  1 
HETATM 6389 C C8  . NAG X 8 .   ? 171.447 215.110 194.394 1.00 30.00  ? 701 NAG B C8  1 
HETATM 6390 N N2  . NAG X 8 .   ? 173.749 214.573 193.998 1.00 30.00  ? 701 NAG B N2  1 
HETATM 6391 O O3  . NAG X 8 .   ? 174.109 214.343 196.836 1.00 30.00  ? 701 NAG B O3  1 
HETATM 6392 O O4  . NAG X 8 .   ? 175.912 216.427 197.871 1.00 30.00  ? 701 NAG B O4  1 
HETATM 6393 O O5  . NAG X 8 .   ? 177.266 215.586 194.542 1.00 30.00  ? 701 NAG B O5  1 
HETATM 6394 O O6  . NAG X 8 .   ? 179.433 216.765 195.530 1.00 30.00  ? 701 NAG B O6  1 
HETATM 6395 O O7  . NAG X 8 .   ? 173.014 216.650 193.503 1.00 30.00  ? 701 NAG B O7  1 
HETATM 6396 C C1  . NAG Y 8 .   ? 193.894 210.614 180.983 1.00 30.00  ? 702 NAG B C1  1 
HETATM 6397 C C2  . NAG Y 8 .   ? 194.200 211.838 181.855 1.00 30.00  ? 702 NAG B C2  1 
HETATM 6398 C C3  . NAG Y 8 .   ? 194.285 213.079 180.975 1.00 30.00  ? 702 NAG B C3  1 
HETATM 6399 C C4  . NAG Y 8 .   ? 195.331 212.871 179.899 1.00 30.00  ? 702 NAG B C4  1 
HETATM 6400 C C5  . NAG Y 8 .   ? 194.996 211.632 179.093 1.00 30.00  ? 702 NAG B C5  1 
HETATM 6401 C C6  . NAG Y 8 .   ? 196.083 211.321 178.080 1.00 30.00  ? 702 NAG B C6  1 
HETATM 6402 C C7  . NAG Y 8 .   ? 192.026 211.733 183.194 1.00 30.00  ? 702 NAG B C7  1 
HETATM 6403 C C8  . NAG Y 8 .   ? 190.929 212.292 182.329 1.00 30.00  ? 702 NAG B C8  1 
HETATM 6404 N N2  . NAG Y 8 .   ? 193.297 212.097 182.983 1.00 30.00  ? 702 NAG B N2  1 
HETATM 6405 O O3  . NAG Y 8 .   ? 194.640 214.216 181.766 1.00 30.00  ? 702 NAG B O3  1 
HETATM 6406 O O4  . NAG Y 8 .   ? 195.339 214.015 179.049 1.00 30.00  ? 702 NAG B O4  1 
HETATM 6407 O O5  . NAG Y 8 .   ? 194.896 210.520 179.971 1.00 30.00  ? 702 NAG B O5  1 
HETATM 6408 O O6  . NAG Y 8 .   ? 195.729 210.126 177.379 1.00 30.00  ? 702 NAG B O6  1 
HETATM 6409 O O7  . NAG Y 8 .   ? 191.758 210.978 184.107 1.00 30.00  ? 702 NAG B O7  1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   0   ?   ?   ?   A . n 
A 1 2   GLY 2   1   ?   ?   ?   A . n 
A 1 3   ILE 3   2   ?   ?   ?   A . n 
A 1 4   LEU 4   3   ?   ?   ?   A . n 
A 1 5   PRO 5   4   ?   ?   ?   A . n 
A 1 6   SER 6   5   ?   ?   ?   A . n 
A 1 7   PRO 7   6   ?   ?   ?   A . n 
A 1 8   GLY 8   7   ?   ?   ?   A . n 
A 1 9   MET 9   8   ?   ?   ?   A . n 
A 1 10  PRO 10  9   ?   ?   ?   A . n 
A 1 11  ALA 11  10  ?   ?   ?   A . n 
A 1 12  LEU 12  11  ?   ?   ?   A . n 
A 1 13  LEU 13  12  ?   ?   ?   A . n 
A 1 14  SER 14  13  ?   ?   ?   A . n 
A 1 15  LEU 15  14  ?   ?   ?   A . n 
A 1 16  VAL 16  15  ?   ?   ?   A . n 
A 1 17  SER 17  16  ?   ?   ?   A . n 
A 1 18  LEU 18  17  ?   ?   ?   A . n 
A 1 19  LEU 19  18  ?   ?   ?   A . n 
A 1 20  SER 20  19  ?   ?   ?   A . n 
A 1 21  VAL 21  20  ?   ?   ?   A . n 
A 1 22  LEU 22  21  ?   ?   ?   A . n 
A 1 23  LEU 23  22  ?   ?   ?   A . n 
A 1 24  MET 24  23  ?   ?   ?   A . n 
A 1 25  GLY 25  24  ?   ?   ?   A . n 
A 1 26  CYS 26  25  ?   ?   ?   A . n 
A 1 27  VAL 27  26  ?   ?   ?   A . n 
A 1 28  ALA 28  27  ?   ?   ?   A . n 
A 1 29  GLU 29  28  ?   ?   ?   A . n 
A 1 30  THR 30  29  ?   ?   ?   A . n 
A 1 31  GLY 31  30  ?   ?   ?   A . n 
A 1 32  ALA 32  31  ?   ?   ?   A . n 
A 1 33  GLU 33  32  ?   ?   ?   A . n 
A 1 34  ASN 34  33  33  ASN ASN A . n 
A 1 35  LEU 35  34  34  LEU LEU A . n 
A 1 36  TRP 36  35  35  TRP TRP A . n 
A 1 37  VAL 37  36  36  VAL VAL A . n 
A 1 38  THR 38  37  37  THR THR A . n 
A 1 39  VAL 39  38  38  VAL VAL A . n 
A 1 40  TYR 40  39  39  TYR TYR A . n 
A 1 41  TYR 41  40  40  TYR TYR A . n 
A 1 42  GLY 42  41  41  GLY GLY A . n 
A 1 43  VAL 43  42  42  VAL VAL A . n 
A 1 44  PRO 44  43  43  PRO PRO A . n 
A 1 45  VAL 45  44  44  VAL VAL A . n 
A 1 46  TRP 46  45  45  TRP TRP A . n 
A 1 47  LYS 47  46  46  LYS LYS A . n 
A 1 48  ASP 48  47  47  ASP ASP A . n 
A 1 49  ALA 49  48  48  ALA ALA A . n 
A 1 50  GLU 50  49  49  GLU GLU A . n 
A 1 51  THR 51  50  50  THR THR A . n 
A 1 52  THR 52  51  51  THR THR A . n 
A 1 53  LEU 53  52  52  LEU LEU A . n 
A 1 54  PHE 54  53  53  PHE PHE A . n 
A 1 55  CYS 55  54  54  CYS CYS A . n 
A 1 56  ALA 56  55  55  ALA ALA A . n 
A 1 57  SER 57  56  56  SER SER A . n 
A 1 58  ASP 58  57  57  ASP ASP A . n 
A 1 59  ALA 59  58  ?   ?   ?   A . n 
A 1 60  LYS 60  59  ?   ?   ?   A . n 
A 1 61  ALA 61  60  ?   ?   ?   A . n 
A 1 62  TYR 62  61  ?   ?   ?   A . n 
A 1 63  GLU 63  62  ?   ?   ?   A . n 
A 1 64  THR 64  63  ?   ?   ?   A . n 
A 1 65  GLU 65  64  ?   ?   ?   A . n 
A 1 66  LYS 66  65  ?   ?   ?   A . n 
A 1 67  HIS 67  66  ?   ?   ?   A . n 
A 1 68  ASN 68  67  ?   ?   ?   A . n 
A 1 69  VAL 69  68  ?   ?   ?   A . n 
A 1 70  TRP 70  69  ?   ?   ?   A . n 
A 1 71  ALA 71  70  ?   ?   ?   A . n 
A 1 72  THR 72  71  ?   ?   ?   A . n 
A 1 73  HIS 73  72  ?   ?   ?   A . n 
A 1 74  ALA 74  73  ?   ?   ?   A . n 
A 1 75  CYS 75  74  ?   ?   ?   A . n 
A 1 76  VAL 76  75  ?   ?   ?   A . n 
A 1 77  PRO 77  76  ?   ?   ?   A . n 
A 1 78  THR 78  77  ?   ?   ?   A . n 
A 1 79  ASP 79  78  ?   ?   ?   A . n 
A 1 80  PRO 80  79  ?   ?   ?   A . n 
A 1 81  ASN 81  80  ?   ?   ?   A . n 
A 1 82  PRO 82  81  ?   ?   ?   A . n 
A 1 83  GLN 83  82  82  GLN GLN A . n 
A 1 84  GLU 84  83  83  GLU GLU A . n 
A 1 85  ILE 85  84  84  ILE ILE A . n 
A 1 86  HIS 86  85  85  HIS HIS A . n 
A 1 87  LEU 87  86  86  LEU LEU A . n 
A 1 88  GLU 88  87  87  GLU GLU A . n 
A 1 89  ASN 89  88  88  ASN ASN A . n 
A 1 90  VAL 90  89  89  VAL VAL A . n 
A 1 91  THR 91  90  90  THR THR A . n 
A 1 92  GLU 92  91  91  GLU GLU A . n 
A 1 93  GLU 93  92  92  GLU GLU A . n 
A 1 94  PHE 94  93  93  PHE PHE A . n 
A 1 95  ASN 95  94  94  ASN ASN A . n 
A 1 96  MET 96  95  95  MET MET A . n 
A 1 97  TRP 97  96  96  TRP TRP A . n 
A 1 98  LYS 98  97  97  LYS LYS A . n 
A 1 99  ASN 99  98  98  ASN ASN A . n 
A 1 100 ASN 100 99  99  ASN ASN A . n 
A 1 101 MET 101 100 100 MET MET A . n 
A 1 102 VAL 102 101 101 VAL VAL A . n 
A 1 103 GLU 103 102 102 GLU GLU A . n 
A 1 104 GLN 104 103 103 GLN GLN A . n 
A 1 105 MET 105 104 104 MET MET A . n 
A 1 106 HIS 106 105 105 HIS HIS A . n 
A 1 107 GLU 107 106 106 GLU GLU A . n 
A 1 108 ASP 108 107 107 ASP ASP A . n 
A 1 109 ILE 109 108 108 ILE ILE A . n 
A 1 110 ILE 110 109 109 ILE ILE A . n 
A 1 111 SER 111 110 110 SER SER A . n 
A 1 112 LEU 112 111 111 LEU LEU A . n 
A 1 113 TRP 113 112 112 TRP TRP A . n 
A 1 114 ASP 114 113 113 ASP ASP A . n 
A 1 115 GLN 115 114 114 GLN GLN A . n 
A 1 116 SER 116 115 115 SER SER A . n 
A 1 117 LEU 117 116 116 LEU LEU A . n 
A 1 118 LYS 118 117 117 LYS LYS A . n 
A 1 119 PRO 119 118 118 PRO PRO A . n 
A 1 120 CYS 120 119 119 CYS CYS A . n 
A 1 121 VAL 121 120 120 VAL VAL A . n 
A 1 122 LYS 122 121 121 LYS LYS A . n 
A 1 123 LEU 123 122 122 LEU LEU A . n 
A 1 124 THR 124 123 123 THR THR A . n 
A 1 125 PRO 125 124 124 PRO PRO A . n 
A 1 126 LEU 126 125 125 LEU LEU A . n 
A 1 127 CYS 127 126 126 CYS CYS A . n 
A 1 128 VAL 128 127 127 VAL VAL A . n 
A 1 129 THR 129 128 128 THR THR A . n 
A 1 130 LEU 130 129 129 LEU LEU A . n 
A 1 131 GLN 131 130 130 GLN GLN A . n 
A 1 132 CYS 132 131 131 CYS CYS A . n 
A 1 133 THR 133 132 132 THR THR A . n 
A 1 134 ASN 134 133 133 ASN ASN A . n 
A 1 135 VAL 135 134 134 VAL VAL A . n 
A 1 136 THR 136 135 135 THR THR A . n 
A 1 137 ASN 137 136 136 ASN ASN A . n 
A 1 138 ASN 138 137 137 ASN ASN A . n 
A 1 139 ILE 139 138 138 ILE ILE A . n 
A 1 140 THR 140 139 139 THR THR A . n 
A 1 141 ASP 141 140 140 ASP ASP A . n 
A 1 142 ASP 142 141 141 ASP ASP A . n 
A 1 143 MET 143 142 142 MET MET A . n 
A 1 144 ARG 144 143 143 ARG ARG A . n 
A 1 145 GLY 145 152 152 GLY GLY A . n 
A 1 146 GLU 146 153 153 GLU GLU A . n 
A 1 147 LEU 147 154 154 LEU LEU A . n 
A 1 148 LYS 148 155 155 LYS LYS A . n 
A 1 149 ASN 149 156 156 ASN ASN A . n 
A 1 150 CYS 150 157 157 CYS CYS A . n 
A 1 151 SER 151 158 158 SER SER A . n 
A 1 152 PHE 152 159 159 PHE PHE A . n 
A 1 153 ASN 153 160 160 ASN ASN A . n 
A 1 154 ALA 154 161 161 ALA ALA A . n 
A 1 155 THR 155 162 162 THR THR A . n 
A 1 156 THR 156 163 163 THR THR A . n 
A 1 157 GLU 157 164 164 GLU GLU A . n 
A 1 158 LEU 158 165 165 LEU LEU A . n 
A 1 159 ARG 159 166 166 ARG ARG A . n 
A 1 160 ASN 160 167 167 ASN ASN A . n 
A 1 161 LYS 161 168 168 LYS LYS A . n 
A 1 162 ARG 162 169 169 ARG ARG A . n 
A 1 163 GLN 163 170 170 GLN GLN A . n 
A 1 164 LYS 164 171 171 LYS LYS A . n 
A 1 165 VAL 165 172 172 VAL VAL A . n 
A 1 166 TYR 166 173 173 TYR TYR A . n 
A 1 167 SER 167 174 174 SER SER A . n 
A 1 168 LEU 168 175 175 LEU LEU A . n 
A 1 169 PHE 169 176 176 PHE PHE A . n 
A 1 170 TYR 170 177 177 TYR TYR A . n 
A 1 171 ARG 171 178 178 ARG ARG A . n 
A 1 172 LEU 172 179 179 LEU LEU A . n 
A 1 173 ASP 173 180 180 ASP ASP A . n 
A 1 174 ILE 174 181 181 ILE ILE A . n 
A 1 175 VAL 175 182 182 VAL VAL A . n 
A 1 176 PRO 176 183 183 PRO PRO A . n 
A 1 177 MET 177 184 184 MET MET A . n 
A 1 178 GLY 178 185 185 GLY GLY A . n 
A 1 179 GLU 179 186 186 GLU GLU A . n 
A 1 180 ASN 180 187 187 ASN ASN A . n 
A 1 181 SER 181 188 188 SER SER A . n 
A 1 182 THR 182 189 189 THR THR A . n 
A 1 183 ASN 183 190 190 ASN ASN A . n 
A 1 184 TYR 184 191 191 TYR TYR A . n 
A 1 185 ARG 185 192 192 ARG ARG A . n 
A 1 186 LEU 186 193 193 LEU LEU A . n 
A 1 187 ILE 187 194 194 ILE ILE A . n 
A 1 188 ASN 188 195 195 ASN ASN A . n 
A 1 189 CYS 189 196 196 CYS CYS A . n 
A 1 190 ASN 190 197 197 ASN ASN A . n 
A 1 191 THR 191 198 198 THR THR A . n 
A 1 192 SER 192 199 199 SER SER A . n 
A 1 193 ALA 193 200 200 ALA ALA A . n 
A 1 194 ILE 194 201 201 ILE ILE A . n 
A 1 195 THR 195 202 202 THR THR A . n 
A 1 196 GLN 196 203 203 GLN GLN A . n 
A 1 197 ALA 197 204 204 ALA ALA A . n 
A 1 198 CYS 198 205 205 CYS CYS A . n 
A 1 199 PRO 199 206 206 PRO PRO A . n 
A 1 200 LYS 200 207 207 LYS LYS A . n 
A 1 201 VAL 201 208 208 VAL VAL A . n 
A 1 202 SER 202 209 209 SER SER A . n 
A 1 203 PHE 203 210 210 PHE PHE A . n 
A 1 204 GLU 204 211 211 GLU GLU A . n 
A 1 205 PRO 205 212 212 PRO PRO A . n 
A 1 206 ILE 206 213 213 ILE ILE A . n 
A 1 207 PRO 207 214 214 PRO PRO A . n 
A 1 208 ILE 208 215 215 ILE ILE A . n 
A 1 209 HIS 209 216 216 HIS HIS A . n 
A 1 210 TYR 210 217 217 TYR TYR A . n 
A 1 211 CYS 211 218 218 CYS CYS A . n 
A 1 212 ALA 212 219 219 ALA ALA A . n 
A 1 213 PRO 213 220 220 PRO PRO A . n 
A 1 214 ALA 214 221 221 ALA ALA A . n 
A 1 215 GLY 215 222 222 GLY GLY A . n 
A 1 216 PHE 216 223 223 PHE PHE A . n 
A 1 217 ALA 217 224 224 ALA ALA A . n 
A 1 218 ILE 218 225 225 ILE ILE A . n 
A 1 219 LEU 219 226 226 LEU LEU A . n 
A 1 220 LYS 220 227 227 LYS LYS A . n 
A 1 221 CYS 221 228 228 CYS CYS A . n 
A 1 222 LYS 222 229 229 LYS LYS A . n 
A 1 223 ASP 223 230 230 ASP ASP A . n 
A 1 224 LYS 224 231 231 LYS LYS A . n 
A 1 225 LYS 225 232 232 LYS LYS A . n 
A 1 226 PHE 226 233 233 PHE PHE A . n 
A 1 227 ASN 227 234 234 ASN ASN A . n 
A 1 228 GLY 228 235 235 GLY GLY A . n 
A 1 229 THR 229 236 236 THR THR A . n 
A 1 230 GLY 230 237 237 GLY GLY A . n 
A 1 231 PRO 231 238 238 PRO PRO A . n 
A 1 232 CYS 232 239 239 CYS CYS A . n 
A 1 233 PRO 233 240 240 PRO PRO A . n 
A 1 234 SER 234 241 241 SER SER A . n 
A 1 235 VAL 235 242 242 VAL VAL A . n 
A 1 236 SER 236 243 243 SER SER A . n 
A 1 237 THR 237 244 244 THR THR A . n 
A 1 238 VAL 238 245 245 VAL VAL A . n 
A 1 239 GLN 239 246 246 GLN GLN A . n 
A 1 240 CYS 240 247 247 CYS CYS A . n 
A 1 241 THR 241 248 248 THR THR A . n 
A 1 242 HIS 242 249 249 HIS HIS A . n 
A 1 243 GLY 243 250 250 GLY GLY A . n 
A 1 244 ILE 244 251 251 ILE ILE A . n 
A 1 245 LYS 245 252 252 LYS LYS A . n 
A 1 246 PRO 246 253 253 PRO PRO A . n 
A 1 247 VAL 247 254 254 VAL VAL A . n 
A 1 248 VAL 248 255 255 VAL VAL A . n 
A 1 249 SER 249 256 256 SER SER A . n 
A 1 250 THR 250 257 257 THR THR A . n 
A 1 251 GLN 251 258 258 GLN GLN A . n 
A 1 252 LEU 252 259 259 LEU LEU A . n 
A 1 253 LEU 253 260 260 LEU LEU A . n 
A 1 254 LEU 254 261 261 LEU LEU A . n 
A 1 255 ASN 255 262 262 ASN ASN A . n 
A 1 256 GLY 256 263 263 GLY GLY A . n 
A 1 257 SER 257 264 264 SER SER A . n 
A 1 258 LEU 258 265 265 LEU LEU A . n 
A 1 259 ALA 259 266 266 ALA ALA A . n 
A 1 260 GLU 260 267 267 GLU GLU A . n 
A 1 261 GLU 261 268 268 GLU GLU A . n 
A 1 262 GLU 262 269 269 GLU GLU A . n 
A 1 263 VAL 263 270 270 VAL VAL A . n 
A 1 264 ILE 264 271 271 ILE ILE A . n 
A 1 265 ILE 265 272 272 ILE ILE A . n 
A 1 266 ARG 266 273 273 ARG ARG A . n 
A 1 267 SER 267 274 274 SER SER A . n 
A 1 268 GLU 268 275 275 GLU GLU A . n 
A 1 269 ASN 269 276 276 ASN ASN A . n 
A 1 270 ILE 270 277 277 ILE ILE A . n 
A 1 271 THR 271 278 278 THR THR A . n 
A 1 272 ASN 272 279 279 ASN ASN A . n 
A 1 273 ASN 273 280 280 ASN ASN A . n 
A 1 274 ALA 274 281 281 ALA ALA A . n 
A 1 275 LYS 275 282 282 LYS LYS A . n 
A 1 276 ASN 276 283 283 ASN ASN A . n 
A 1 277 ILE 277 284 284 ILE ILE A . n 
A 1 278 LEU 278 285 285 LEU LEU A . n 
A 1 279 VAL 279 286 286 VAL VAL A . n 
A 1 280 GLN 280 287 287 GLN GLN A . n 
A 1 281 LEU 281 288 288 LEU LEU A . n 
A 1 282 ASN 282 289 289 ASN ASN A . n 
A 1 283 THR 283 290 290 THR THR A . n 
A 1 284 PRO 284 291 291 PRO PRO A . n 
A 1 285 VAL 285 292 292 VAL VAL A . n 
A 1 286 GLN 286 293 293 GLN GLN A . n 
A 1 287 ILE 287 294 294 ILE ILE A . n 
A 1 288 ASN 288 295 295 ASN ASN A . n 
A 1 289 CYS 289 296 296 CYS CYS A . n 
A 1 290 THR 290 297 297 THR THR A . n 
A 1 291 ARG 291 298 298 ARG ARG A . n 
A 1 292 PRO 292 299 299 PRO PRO A . n 
A 1 293 ASN 293 300 300 ASN ASN A . n 
A 1 294 ASN 294 301 301 ASN ASN A . n 
A 1 295 ASN 295 302 302 ASN ASN A . n 
A 1 296 THR 296 303 303 THR THR A . n 
A 1 297 VAL 297 304 304 VAL VAL A . n 
A 1 298 LYS 298 305 305 LYS LYS A . n 
A 1 299 SER 299 306 306 SER SER A . n 
A 1 300 ILE 300 307 307 ILE ILE A . n 
A 1 301 ARG 301 308 308 ARG ARG A . n 
A 1 302 ILE 302 309 309 ILE ILE A . n 
A 1 303 GLY 303 312 312 GLY GLY A . n 
A 1 304 PRO 304 313 313 PRO PRO A . n 
A 1 305 GLY 305 314 314 GLY GLY A . n 
A 1 306 GLN 306 315 315 GLN GLN A . n 
A 1 307 ALA 307 316 316 ALA ALA A . n 
A 1 308 PHE 308 317 317 PHE PHE A . n 
A 1 309 TYR 309 318 318 TYR TYR A . n 
A 1 310 TYR 310 319 319 TYR TYR A . n 
A 1 311 THR 311 320 320 THR THR A . n 
A 1 312 GLY 312 321 321 GLY GLY A . n 
A 1 313 ASP 313 322 322 ASP ASP A . n 
A 1 314 ILE 314 323 323 ILE ILE A . n 
A 1 315 ILE 315 323 323 ILE ILE A A n 
A 1 316 GLY 316 324 324 GLY GLY A . n 
A 1 317 ASP 317 325 325 ASP ASP A . n 
A 1 318 ILE 318 326 326 ILE ILE A . n 
A 1 319 ARG 319 327 327 ARG ARG A . n 
A 1 320 GLN 320 328 328 GLN GLN A . n 
A 1 321 ALA 321 329 329 ALA ALA A . n 
A 1 322 HIS 322 330 330 HIS HIS A . n 
A 1 323 CYS 323 331 331 CYS CYS A . n 
A 1 324 ASN 324 332 332 ASN ASN A . n 
A 1 325 VAL 325 333 333 VAL VAL A . n 
A 1 326 SER 326 334 334 SER SER A . n 
A 1 327 LYS 327 335 335 LYS LYS A . n 
A 1 328 ALA 328 336 336 ALA ALA A . n 
A 1 329 THR 329 337 337 THR THR A . n 
A 1 330 TRP 330 338 338 TRP TRP A . n 
A 1 331 ASN 331 339 339 ASN ASN A . n 
A 1 332 GLU 332 340 340 GLU GLU A . n 
A 1 333 THR 333 341 341 THR THR A . n 
A 1 334 LEU 334 342 342 LEU LEU A . n 
A 1 335 GLY 335 343 343 GLY GLY A . n 
A 1 336 LYS 336 344 344 LYS LYS A . n 
A 1 337 VAL 337 345 345 VAL VAL A . n 
A 1 338 VAL 338 346 346 VAL VAL A . n 
A 1 339 LYS 339 347 347 LYS LYS A . n 
A 1 340 GLN 340 348 348 GLN GLN A . n 
A 1 341 LEU 341 349 349 LEU LEU A . n 
A 1 342 ARG 342 350 350 ARG ARG A . n 
A 1 343 LYS 343 351 351 LYS LYS A . n 
A 1 344 HIS 344 352 352 HIS HIS A . n 
A 1 345 PHE 345 353 353 PHE PHE A . n 
A 1 346 GLY 346 354 354 GLY GLY A . n 
A 1 347 ASN 347 355 355 ASN ASN A . n 
A 1 348 ASN 348 356 356 ASN ASN A . n 
A 1 349 THR 349 357 357 THR THR A . n 
A 1 350 ILE 350 358 358 ILE ILE A . n 
A 1 351 ILE 351 359 359 ILE ILE A . n 
A 1 352 ARG 352 360 360 ARG ARG A . n 
A 1 353 PHE 353 361 361 PHE PHE A . n 
A 1 354 ALA 354 362 362 ALA ALA A . n 
A 1 355 GLN 355 363 363 GLN GLN A . n 
A 1 356 SER 356 364 364 SER SER A . n 
A 1 357 SER 357 365 365 SER SER A . n 
A 1 358 GLY 358 366 366 GLY GLY A . n 
A 1 359 GLY 359 367 367 GLY GLY A . n 
A 1 360 ASP 360 368 368 ASP ASP A . n 
A 1 361 LEU 361 369 369 LEU LEU A . n 
A 1 362 GLU 362 370 370 GLU GLU A . n 
A 1 363 VAL 363 371 371 VAL VAL A . n 
A 1 364 THR 364 372 372 THR THR A . n 
A 1 365 THR 365 373 373 THR THR A . n 
A 1 366 HIS 366 374 374 HIS HIS A . n 
A 1 367 SER 367 375 375 SER SER A . n 
A 1 368 PHE 368 376 376 PHE PHE A . n 
A 1 369 ASN 369 377 377 ASN ASN A . n 
A 1 370 CYS 370 378 378 CYS CYS A . n 
A 1 371 GLY 371 379 379 GLY GLY A . n 
A 1 372 GLY 372 380 380 GLY GLY A . n 
A 1 373 GLU 373 381 381 GLU GLU A . n 
A 1 374 PHE 374 382 382 PHE PHE A . n 
A 1 375 PHE 375 383 383 PHE PHE A . n 
A 1 376 TYR 376 384 384 TYR TYR A . n 
A 1 377 CYS 377 385 385 CYS CYS A . n 
A 1 378 ASN 378 386 386 ASN ASN A . n 
A 1 379 THR 379 387 387 THR THR A . n 
A 1 380 SER 380 388 388 SER SER A . n 
A 1 381 GLY 381 389 389 GLY GLY A . n 
A 1 382 LEU 382 390 390 LEU LEU A . n 
A 1 383 PHE 383 391 391 PHE PHE A . n 
A 1 384 ASN 384 392 392 ASN ASN A . n 
A 1 385 SER 385 393 393 SER SER A . n 
A 1 386 THR 386 394 394 THR THR A . n 
A 1 387 TRP 387 395 395 TRP TRP A . n 
A 1 388 ILE 388 396 396 ILE ILE A . n 
A 1 389 SER 389 397 397 SER SER A . n 
A 1 390 ASN 390 397 ?   ?   ?   A A n 
A 1 391 THR 391 397 ?   ?   ?   A B n 
A 1 392 SER 392 397 ?   ?   ?   A C n 
A 1 393 VAL 393 397 ?   ?   ?   A D n 
A 1 394 GLN 394 397 ?   ?   ?   A E n 
A 1 395 GLY 395 397 ?   ?   ?   A F n 
A 1 396 SER 396 397 ?   ?   ?   A G n 
A 1 397 ASN 397 397 ?   ?   ?   A H n 
A 1 398 SER 398 397 ?   ?   ?   A I n 
A 1 399 THR 399 397 ?   ?   ?   A J n 
A 1 400 GLY 400 397 ?   ?   ?   A K n 
A 1 401 SER 401 397 ?   ?   ?   A L n 
A 1 402 ASN 402 399 399 ASN ASN A . n 
A 1 403 ASP 403 412 412 ASP ASP A . n 
A 1 404 SER 404 413 413 SER SER A . n 
A 1 405 ILE 405 414 414 ILE ILE A . n 
A 1 406 THR 406 415 415 THR THR A . n 
A 1 407 LEU 407 416 416 LEU LEU A . n 
A 1 408 PRO 408 417 417 PRO PRO A . n 
A 1 409 CYS 409 418 418 CYS CYS A . n 
A 1 410 ARG 410 419 419 ARG ARG A . n 
A 1 411 ILE 411 420 420 ILE ILE A . n 
A 1 412 LYS 412 421 421 LYS LYS A . n 
A 1 413 GLN 413 422 422 GLN GLN A . n 
A 1 414 ILE 414 423 423 ILE ILE A . n 
A 1 415 ILE 415 424 424 ILE ILE A . n 
A 1 416 ASN 416 425 425 ASN ASN A . n 
A 1 417 MET 417 426 426 MET MET A . n 
A 1 418 TRP 418 427 427 TRP TRP A . n 
A 1 419 GLN 419 428 428 GLN GLN A . n 
A 1 420 ARG 420 429 429 ARG ARG A . n 
A 1 421 ILE 421 430 430 ILE ILE A . n 
A 1 422 GLY 422 431 431 GLY GLY A . n 
A 1 423 GLN 423 432 432 GLN GLN A . n 
A 1 424 ALA 424 433 433 ALA ALA A . n 
A 1 425 MET 425 434 434 MET MET A . n 
A 1 426 TYR 426 435 435 TYR TYR A . n 
A 1 427 ALA 427 436 436 ALA ALA A . n 
A 1 428 PRO 428 437 437 PRO PRO A . n 
A 1 429 PRO 429 438 438 PRO PRO A . n 
A 1 430 ILE 430 439 439 ILE ILE A . n 
A 1 431 GLN 431 440 440 GLN GLN A . n 
A 1 432 GLY 432 441 441 GLY GLY A . n 
A 1 433 VAL 433 442 442 VAL VAL A . n 
A 1 434 ILE 434 443 443 ILE ILE A . n 
A 1 435 ARG 435 444 444 ARG ARG A . n 
A 1 436 CYS 436 445 445 CYS CYS A . n 
A 1 437 VAL 437 446 446 VAL VAL A . n 
A 1 438 SER 438 447 447 SER SER A . n 
A 1 439 ASN 439 448 448 ASN ASN A . n 
A 1 440 ILE 440 449 449 ILE ILE A . n 
A 1 441 THR 441 450 450 THR THR A . n 
A 1 442 GLY 442 451 451 GLY GLY A . n 
A 1 443 LEU 443 452 452 LEU LEU A . n 
A 1 444 ILE 444 453 453 ILE ILE A . n 
A 1 445 LEU 445 454 454 LEU LEU A . n 
A 1 446 THR 446 455 455 THR THR A . n 
A 1 447 ARG 447 456 456 ARG ARG A . n 
A 1 448 ASP 448 457 457 ASP ASP A . n 
A 1 449 GLY 449 458 ?   ?   ?   A . n 
A 1 450 GLY 450 459 ?   ?   ?   A . n 
A 1 451 SER 451 460 ?   ?   ?   A . n 
A 1 452 THR 452 461 ?   ?   ?   A . n 
A 1 453 ASN 453 462 ?   ?   ?   A . n 
A 1 454 SER 454 463 ?   ?   ?   A . n 
A 1 455 THR 455 464 464 THR THR A . n 
A 1 456 THR 456 465 465 THR THR A . n 
A 1 457 GLU 457 466 466 GLU GLU A . n 
A 1 458 THR 458 467 467 THR THR A . n 
A 1 459 PHE 459 468 468 PHE PHE A . n 
A 1 460 ARG 460 469 469 ARG ARG A . n 
A 1 461 PRO 461 470 470 PRO PRO A . n 
A 1 462 GLY 462 471 471 GLY GLY A . n 
A 1 463 GLY 463 472 472 GLY GLY A . n 
A 1 464 GLY 464 473 473 GLY GLY A . n 
A 1 465 ASP 465 474 474 ASP ASP A . n 
A 1 466 MET 466 475 475 MET MET A . n 
A 1 467 ARG 467 476 476 ARG ARG A . n 
A 1 468 ASP 468 477 477 ASP ASP A . n 
A 1 469 ASN 469 478 478 ASN ASN A . n 
A 1 470 TRP 470 479 479 TRP TRP A . n 
A 1 471 ARG 471 480 480 ARG ARG A . n 
A 1 472 SER 472 481 481 SER SER A . n 
A 1 473 GLU 473 482 482 GLU GLU A . n 
A 1 474 LEU 474 483 483 LEU LEU A . n 
A 1 475 TYR 475 484 484 TYR TYR A . n 
A 1 476 LYS 476 485 485 LYS LYS A . n 
A 1 477 TYR 477 486 486 TYR TYR A . n 
A 1 478 LYS 478 487 487 LYS LYS A . n 
A 1 479 VAL 479 488 488 VAL VAL A . n 
A 1 480 VAL 480 489 489 VAL VAL A . n 
A 1 481 LYS 481 490 490 LYS LYS A . n 
A 1 482 ILE 482 491 491 ILE ILE A . n 
A 1 483 GLU 483 492 492 GLU GLU A . n 
A 1 484 PRO 484 493 493 PRO PRO A . n 
A 1 485 LEU 485 494 494 LEU LEU A . n 
A 1 486 GLY 486 495 495 GLY GLY A . n 
A 1 487 VAL 487 496 496 VAL VAL A . n 
A 1 488 ALA 488 497 497 ALA ALA A . n 
A 1 489 PRO 489 498 498 PRO PRO A . n 
A 1 490 THR 490 499 499 THR THR A . n 
A 1 491 ARG 491 500 500 ARG ARG A . n 
A 1 492 CYS 492 501 501 CYS CYS A . n 
A 1 493 LYS 493 502 502 LYS LYS A . n 
A 1 494 ARG 494 503 503 ARG ARG A . n 
A 1 495 ARG 495 504 ?   ?   ?   A . n 
A 1 496 VAL 496 505 ?   ?   ?   A . n 
A 1 497 VAL 497 506 ?   ?   ?   A . n 
A 1 498 GLY 498 507 ?   ?   ?   A . n 
A 1 499 ARG 499 508 ?   ?   ?   A . n 
A 1 500 ARG 500 509 ?   ?   ?   A . n 
A 1 501 ARG 501 510 ?   ?   ?   A . n 
A 1 502 ARG 502 511 ?   ?   ?   A . n 
A 1 503 ARG 503 512 ?   ?   ?   A . n 
A 1 504 ARG 504 513 ?   ?   ?   A . n 
B 2 1   ALA 1   510 ?   ?   ?   B . n 
B 2 2   VAL 2   511 ?   ?   ?   B . n 
B 2 3   GLY 3   512 ?   ?   ?   B . n 
B 2 4   ILE 4   513 ?   ?   ?   B . n 
B 2 5   GLY 5   514 ?   ?   ?   B . n 
B 2 6   ALA 6   515 ?   ?   ?   B . n 
B 2 7   VAL 7   516 ?   ?   ?   B . n 
B 2 8   SER 8   517 ?   ?   ?   B . n 
B 2 9   LEU 9   518 518 LEU LEU B . n 
B 2 10  GLY 10  519 519 GLY GLY B . n 
B 2 11  PHE 11  520 520 PHE PHE B . n 
B 2 12  LEU 12  521 521 LEU LEU B . n 
B 2 13  GLY 13  522 522 GLY GLY B . n 
B 2 14  ALA 14  523 523 ALA ALA B . n 
B 2 15  ALA 15  524 524 ALA ALA B . n 
B 2 16  GLY 16  525 525 GLY GLY B . n 
B 2 17  SER 17  526 526 SER SER B . n 
B 2 18  THR 18  527 527 THR THR B . n 
B 2 19  MET 19  528 528 MET MET B . n 
B 2 20  GLY 20  529 529 GLY GLY B . n 
B 2 21  ALA 21  530 530 ALA ALA B . n 
B 2 22  ALA 22  531 531 ALA ALA B . n 
B 2 23  SER 23  532 532 SER SER B . n 
B 2 24  MET 24  533 533 MET MET B . n 
B 2 25  THR 25  534 534 THR THR B . n 
B 2 26  LEU 26  535 535 LEU LEU B . n 
B 2 27  THR 27  536 536 THR THR B . n 
B 2 28  VAL 28  537 537 VAL VAL B . n 
B 2 29  GLN 29  538 538 GLN GLN B . n 
B 2 30  ALA 30  539 539 ALA ALA B . n 
B 2 31  ARG 31  540 540 ARG ARG B . n 
B 2 32  ASN 32  541 541 ASN ASN B . n 
B 2 33  LEU 33  542 542 LEU LEU B . n 
B 2 34  LEU 34  543 543 LEU LEU B . n 
B 2 35  SER 35  544 544 SER SER B . n 
B 2 36  GLY 36  547 ?   ?   ?   B . n 
B 2 37  ILE 37  548 ?   ?   ?   B . n 
B 2 38  VAL 38  549 ?   ?   ?   B . n 
B 2 39  GLN 39  550 ?   ?   ?   B . n 
B 2 40  GLN 40  551 ?   ?   ?   B . n 
B 2 41  GLN 41  552 ?   ?   ?   B . n 
B 2 42  SER 42  553 ?   ?   ?   B . n 
B 2 43  ASN 43  554 ?   ?   ?   B . n 
B 2 44  LEU 44  555 ?   ?   ?   B . n 
B 2 45  LEU 45  556 ?   ?   ?   B . n 
B 2 46  ARG 46  557 ?   ?   ?   B . n 
B 2 47  ALA 47  558 ?   ?   ?   B . n 
B 2 48  PRO 48  559 ?   ?   ?   B . n 
B 2 49  GLU 49  560 ?   ?   ?   B . n 
B 2 50  PRO 50  561 ?   ?   ?   B . n 
B 2 51  GLN 51  562 ?   ?   ?   B . n 
B 2 52  GLN 52  563 ?   ?   ?   B . n 
B 2 53  HIS 53  564 ?   ?   ?   B . n 
B 2 54  LEU 54  565 ?   ?   ?   B . n 
B 2 55  LEU 55  566 ?   ?   ?   B . n 
B 2 56  LYS 56  567 ?   ?   ?   B . n 
B 2 57  ASP 57  568 ?   ?   ?   B . n 
B 2 58  THR 58  569 ?   ?   ?   B . n 
B 2 59  HIS 59  570 570 HIS HIS B . n 
B 2 60  TRP 60  571 571 TRP TRP B . n 
B 2 61  GLY 61  572 572 GLY GLY B . n 
B 2 62  ILE 62  573 573 ILE ILE B . n 
B 2 63  LYS 63  574 574 LYS LYS B . n 
B 2 64  GLN 64  575 575 GLN GLN B . n 
B 2 65  LEU 65  576 576 LEU LEU B . n 
B 2 66  GLN 66  577 577 GLN GLN B . n 
B 2 67  ALA 67  578 578 ALA ALA B . n 
B 2 68  ARG 68  579 579 ARG ARG B . n 
B 2 69  VAL 69  580 580 VAL VAL B . n 
B 2 70  LEU 70  581 581 LEU LEU B . n 
B 2 71  ALA 71  582 582 ALA ALA B . n 
B 2 72  VAL 72  583 583 VAL VAL B . n 
B 2 73  GLU 73  584 584 GLU GLU B . n 
B 2 74  HIS 74  585 585 HIS HIS B . n 
B 2 75  TYR 75  586 586 TYR TYR B . n 
B 2 76  LEU 76  587 587 LEU LEU B . n 
B 2 77  ARG 77  588 588 ARG ARG B . n 
B 2 78  ASP 78  589 589 ASP ASP B . n 
B 2 79  GLN 79  590 590 GLN GLN B . n 
B 2 80  GLN 80  591 591 GLN GLN B . n 
B 2 81  LEU 81  592 592 LEU LEU B . n 
B 2 82  LEU 82  593 593 LEU LEU B . n 
B 2 83  GLY 83  594 594 GLY GLY B . n 
B 2 84  ILE 84  595 595 ILE ILE B . n 
B 2 85  TRP 85  596 596 TRP TRP B . n 
B 2 86  GLY 86  597 597 GLY GLY B . n 
B 2 87  CYS 87  598 598 CYS CYS B . n 
B 2 88  SER 88  599 599 SER SER B . n 
B 2 89  GLY 89  600 600 GLY GLY B . n 
B 2 90  LYS 90  601 601 LYS LYS B . n 
B 2 91  LEU 91  602 602 LEU LEU B . n 
B 2 92  ILE 92  603 603 ILE ILE B . n 
B 2 93  CYS 93  604 604 CYS CYS B . n 
B 2 94  CYS 94  605 605 CYS CYS B . n 
B 2 95  THR 95  606 606 THR THR B . n 
B 2 96  ASN 96  607 607 ASN ASN B . n 
B 2 97  VAL 97  608 608 VAL VAL B . n 
B 2 98  PRO 98  609 609 PRO PRO B . n 
B 2 99  TRP 99  610 610 TRP TRP B . n 
B 2 100 ASN 100 611 611 ASN ASN B . n 
B 2 101 SER 101 612 612 SER SER B . n 
B 2 102 SER 102 613 613 SER SER B . n 
B 2 103 TRP 103 614 614 TRP TRP B . n 
B 2 104 SER 104 615 615 SER SER B . n 
B 2 105 ASN 105 616 616 ASN ASN B . n 
B 2 106 ARG 106 617 617 ARG ARG B . n 
B 2 107 ASN 107 618 618 ASN ASN B . n 
B 2 108 LEU 108 619 619 LEU LEU B . n 
B 2 109 SER 109 620 620 SER SER B . n 
B 2 110 GLU 110 621 621 GLU GLU B . n 
B 2 111 ILE 111 622 622 ILE ILE B . n 
B 2 112 TRP 112 623 623 TRP TRP B . n 
B 2 113 ASP 113 624 624 ASP ASP B . n 
B 2 114 ASN 114 625 625 ASN ASN B . n 
B 2 115 MET 115 626 626 MET MET B . n 
B 2 116 THR 116 627 627 THR THR B . n 
B 2 117 TRP 117 628 628 TRP TRP B . n 
B 2 118 LEU 118 629 629 LEU LEU B . n 
B 2 119 GLN 119 630 630 GLN GLN B . n 
B 2 120 TRP 120 631 631 TRP TRP B . n 
B 2 121 ASP 121 632 632 ASP ASP B . n 
B 2 122 LYS 122 633 633 LYS LYS B . n 
B 2 123 GLU 123 634 634 GLU GLU B . n 
B 2 124 ILE 124 635 635 ILE ILE B . n 
B 2 125 SER 125 636 636 SER SER B . n 
B 2 126 ASN 126 637 637 ASN ASN B . n 
B 2 127 TYR 127 638 638 TYR TYR B . n 
B 2 128 THR 128 639 639 THR THR B . n 
B 2 129 GLN 129 640 640 GLN GLN B . n 
B 2 130 ILE 130 641 641 ILE ILE B . n 
B 2 131 ILE 131 642 642 ILE ILE B . n 
B 2 132 TYR 132 643 643 TYR TYR B . n 
B 2 133 GLY 133 644 644 GLY GLY B . n 
B 2 134 LEU 134 645 645 LEU LEU B . n 
B 2 135 LEU 135 646 646 LEU LEU B . n 
B 2 136 GLU 136 647 647 GLU GLU B . n 
B 2 137 GLU 137 648 648 GLU GLU B . n 
B 2 138 SER 138 649 649 SER SER B . n 
B 2 139 GLN 139 650 650 GLN GLN B . n 
B 2 140 ASN 140 651 651 ASN ASN B . n 
B 2 141 GLN 141 652 652 GLN GLN B . n 
B 2 142 GLN 142 653 653 GLN GLN B . n 
B 2 143 GLU 143 654 654 GLU GLU B . n 
B 2 144 LYS 144 655 655 LYS LYS B . n 
B 2 145 ASN 145 656 656 ASN ASN B . n 
B 2 146 GLU 146 657 657 GLU GLU B . n 
B 2 147 GLN 147 658 658 GLN GLN B . n 
B 2 148 ASP 148 659 659 ASP ASP B . n 
B 2 149 LEU 149 660 660 LEU LEU B . n 
B 2 150 LEU 150 661 661 LEU LEU B . n 
B 2 151 ALA 151 662 662 ALA ALA B . n 
B 2 152 LEU 152 663 ?   ?   ?   B . n 
B 2 153 ASP 153 664 ?   ?   ?   B . n 
B 2 154 GLY 154 665 ?   ?   ?   B . n 
B 2 155 THR 155 666 ?   ?   ?   B . n 
B 2 156 LYS 156 667 ?   ?   ?   B . n 
B 2 157 HIS 157 668 ?   ?   ?   B . n 
B 2 158 HIS 158 669 ?   ?   ?   B . n 
B 2 159 HIS 159 670 ?   ?   ?   B . n 
B 2 160 HIS 160 671 ?   ?   ?   B . n 
B 2 161 HIS 161 672 ?   ?   ?   B . n 
B 2 162 HIS 162 673 ?   ?   ?   B . n 
C 3 1   GLU 1   1   1   GLU GLU H . n 
C 3 2   VAL 2   2   2   VAL VAL H . n 
C 3 3   GLN 3   3   3   GLN GLN H . n 
C 3 4   LEU 4   4   4   LEU LEU H . n 
C 3 5   VAL 5   5   5   VAL VAL H . n 
C 3 6   GLU 6   6   6   GLU GLU H . n 
C 3 7   THR 7   7   7   THR THR H . n 
C 3 8   GLY 8   8   8   GLY GLY H . n 
C 3 9   GLY 9   9   9   GLY GLY H . n 
C 3 10  GLY 10  10  10  GLY GLY H . n 
C 3 11  LEU 11  11  11  LEU LEU H . n 
C 3 12  VAL 12  12  12  VAL VAL H . n 
C 3 13  GLN 13  13  13  GLN GLN H . n 
C 3 14  PRO 14  14  14  PRO PRO H . n 
C 3 15  GLY 15  15  15  GLY GLY H . n 
C 3 16  GLY 16  16  16  GLY GLY H . n 
C 3 17  SER 17  17  17  SER SER H . n 
C 3 18  LEU 18  18  18  LEU LEU H . n 
C 3 19  LYS 19  19  19  LYS LYS H . n 
C 3 20  LEU 20  20  20  LEU LEU H . n 
C 3 21  SER 21  21  21  SER SER H . n 
C 3 22  CYS 22  22  22  CYS CYS H . n 
C 3 23  ARG 23  23  23  ARG ARG H . n 
C 3 24  ALA 24  24  24  ALA ALA H . n 
C 3 25  SER 25  25  25  SER SER H . n 
C 3 26  GLY 26  26  26  GLY GLY H . n 
C 3 27  TYR 27  27  27  TYR TYR H . n 
C 3 28  THR 28  28  28  THR THR H . n 
C 3 29  PHE 29  29  29  PHE PHE H . n 
C 3 30  SER 30  30  30  SER SER H . n 
C 3 31  SER 31  31  31  SER SER H . n 
C 3 32  PHE 32  32  32  PHE PHE H . n 
C 3 33  ALA 33  33  33  ALA ALA H . n 
C 3 34  MET 34  34  34  MET MET H . n 
C 3 35  SER 35  35  35  SER SER H . n 
C 3 36  TRP 36  36  36  TRP TRP H . n 
C 3 37  VAL 37  37  37  VAL VAL H . n 
C 3 38  ARG 38  38  38  ARG ARG H . n 
C 3 39  GLN 39  39  39  GLN GLN H . n 
C 3 40  ALA 40  40  40  ALA ALA H . n 
C 3 41  PRO 41  41  41  PRO PRO H . n 
C 3 42  GLY 42  42  42  GLY GLY H . n 
C 3 43  LYS 43  43  43  LYS LYS H . n 
C 3 44  GLY 44  44  44  GLY GLY H . n 
C 3 45  LEU 45  45  45  LEU LEU H . n 
C 3 46  GLU 46  46  46  GLU GLU H . n 
C 3 47  TRP 47  47  47  TRP TRP H . n 
C 3 48  VAL 48  48  48  VAL VAL H . n 
C 3 49  SER 49  49  49  SER SER H . n 
C 3 50  LEU 50  50  50  LEU LEU H . n 
C 3 51  ILE 51  51  51  ILE ILE H . n 
C 3 52  ASN 52  52  52  ASN ASN H . n 
C 3 53  ASP 53  52  52  ASP ASP H A n 
C 3 54  ARG 54  53  53  ARG ARG H . n 
C 3 55  GLY 55  54  54  GLY GLY H . n 
C 3 56  GLY 56  55  55  GLY GLY H . n 
C 3 57  LEU 57  56  56  LEU LEU H . n 
C 3 58  THR 58  57  57  THR THR H . n 
C 3 59  PHE 59  58  58  PHE PHE H . n 
C 3 60  TYR 60  59  59  TYR TYR H . n 
C 3 61  VAL 61  60  60  VAL VAL H . n 
C 3 62  ASP 62  61  61  ASP ASP H . n 
C 3 63  SER 63  62  62  SER SER H . n 
C 3 64  VAL 64  63  63  VAL VAL H . n 
C 3 65  LYS 65  64  64  LYS LYS H . n 
C 3 66  GLY 66  65  65  GLY GLY H . n 
C 3 67  ARG 67  66  66  ARG ARG H . n 
C 3 68  PHE 68  67  67  PHE PHE H . n 
C 3 69  THR 69  68  68  THR THR H . n 
C 3 70  ILE 70  69  69  ILE ILE H . n 
C 3 71  SER 71  70  70  SER SER H . n 
C 3 72  ARG 72  71  71  ARG ARG H . n 
C 3 73  ASP 73  72  72  ASP ASP H . n 
C 3 74  ASN 74  73  73  ASN ASN H . n 
C 3 75  SER 75  74  74  SER SER H . n 
C 3 76  LYS 76  75  75  LYS LYS H . n 
C 3 77  ASN 77  76  76  ASN ASN H . n 
C 3 78  THR 78  77  77  THR THR H . n 
C 3 79  LEU 79  78  78  LEU LEU H . n 
C 3 80  SER 80  79  79  SER SER H . n 
C 3 81  LEU 81  80  80  LEU LEU H . n 
C 3 82  GLN 82  81  81  GLN GLN H . n 
C 3 83  MET 83  82  82  MET MET H . n 
C 3 84  HIS 84  82  82  HIS HIS H A n 
C 3 85  SER 85  82  82  SER SER H B n 
C 3 86  LEU 86  82  82  LEU LEU H C n 
C 3 87  ARG 87  83  83  ARG ARG H . n 
C 3 88  ASP 88  84  84  ASP ASP H . n 
C 3 89  GLY 89  85  85  GLY GLY H . n 
C 3 90  ASP 90  86  86  ASP ASP H . n 
C 3 91  THR 91  87  87  THR THR H . n 
C 3 92  ALA 92  88  88  ALA ALA H . n 
C 3 93  VAL 93  89  89  VAL VAL H . n 
C 3 94  TYR 94  90  90  TYR TYR H . n 
C 3 95  TYR 95  91  91  TYR TYR H . n 
C 3 96  CYS 96  92  92  CYS CYS H . n 
C 3 97  ALA 97  93  93  ALA ALA H . n 
C 3 98  THR 98  94  94  THR THR H . n 
C 3 99  GLY 99  95  95  GLY GLY H . n 
C 3 100 GLY 100 96  96  GLY GLY H . n 
C 3 101 MET 101 97  97  MET MET H . n 
C 3 102 SER 102 98  98  SER SER H . n 
C 3 103 SER 103 99  99  SER SER H . n 
C 3 104 ALA 104 100 100 ALA ALA H . n 
C 3 105 LEU 105 100 100 LEU LEU H A n 
C 3 106 GLN 106 100 100 GLN GLN H B n 
C 3 107 SER 107 100 100 SER SER H C n 
C 3 108 SER 108 100 100 SER SER H D n 
C 3 109 LYS 109 100 100 LYS LYS H E n 
C 3 110 TYR 110 100 100 TYR TYR H F n 
C 3 111 TYR 111 100 100 TYR TYR H G n 
C 3 112 PHE 112 100 100 PHE PHE H H n 
C 3 113 ASP 113 101 101 ASP ASP H . n 
C 3 114 PHE 114 102 102 PHE PHE H . n 
C 3 115 TRP 115 103 103 TRP TRP H . n 
C 3 116 GLY 116 104 104 GLY GLY H . n 
C 3 117 GLN 117 105 105 GLN GLN H . n 
C 3 118 GLY 118 106 106 GLY GLY H . n 
C 3 119 ALA 119 107 107 ALA ALA H . n 
C 3 120 LEU 120 108 108 LEU LEU H . n 
C 3 121 VAL 121 109 109 VAL VAL H . n 
C 3 122 THR 122 110 110 THR THR H . n 
C 3 123 VAL 123 111 111 VAL VAL H . n 
C 3 124 SER 124 112 112 SER SER H . n 
C 3 125 SER 125 113 ?   ?   ?   H . n 
D 4 1   ALA 1   3   3   ALA ALA L . n 
D 4 2   LEU 2   4   4   LEU LEU L . n 
D 4 3   THR 3   5   5   THR THR L . n 
D 4 4   GLN 4   6   6   GLN GLN L . n 
D 4 5   PRO 5   7   7   PRO PRO L . n 
D 4 6   PRO 6   8   8   PRO PRO L . n 
D 4 7   SER 7   9   9   SER SER L . n 
D 4 8   VAL 8   11  11  VAL VAL L . n 
D 4 9   SER 9   12  12  SER SER L . n 
D 4 10  GLY 10  13  13  GLY GLY L . n 
D 4 11  SER 11  14  14  SER SER L . n 
D 4 12  PRO 12  15  15  PRO PRO L . n 
D 4 13  GLY 13  16  16  GLY GLY L . n 
D 4 14  GLN 14  17  17  GLN GLN L . n 
D 4 15  SER 15  18  18  SER SER L . n 
D 4 16  VAL 16  19  19  VAL VAL L . n 
D 4 17  THR 17  20  20  THR THR L . n 
D 4 18  ILE 18  21  21  ILE ILE L . n 
D 4 19  SER 19  22  22  SER SER L . n 
D 4 20  CYS 20  23  23  CYS CYS L . n 
D 4 21  THR 21  24  24  THR THR L . n 
D 4 22  GLY 22  25  25  GLY GLY L . n 
D 4 23  THR 23  26  26  THR THR L . n 
D 4 24  SER 24  27  27  SER SER L . n 
D 4 25  SER 25  27  27  SER SER L A n 
D 4 26  ASP 26  27  27  ASP ASP L B n 
D 4 27  ILE 27  27  27  ILE ILE L C n 
D 4 28  GLY 28  28  28  GLY GLY L . n 
D 4 29  SER 29  29  29  SER SER L . n 
D 4 30  TYR 30  30  30  TYR TYR L . n 
D 4 31  ASN 31  31  31  ASN ASN L . n 
D 4 32  TYR 32  32  32  TYR TYR L . n 
D 4 33  VAL 33  33  33  VAL VAL L . n 
D 4 34  SER 34  34  34  SER SER L . n 
D 4 35  TRP 35  35  35  TRP TRP L . n 
D 4 36  TYR 36  36  36  TYR TYR L . n 
D 4 37  GLN 37  37  37  GLN GLN L . n 
D 4 38  GLN 38  38  38  GLN GLN L . n 
D 4 39  HIS 39  39  39  HIS HIS L . n 
D 4 40  PRO 40  40  40  PRO PRO L . n 
D 4 41  GLY 41  41  41  GLY GLY L . n 
D 4 42  LYS 42  42  42  LYS LYS L . n 
D 4 43  ALA 43  43  43  ALA ALA L . n 
D 4 44  PRO 44  44  44  PRO PRO L . n 
D 4 45  LYS 45  45  45  LYS LYS L . n 
D 4 46  LEU 46  46  46  LEU LEU L . n 
D 4 47  MET 47  47  47  MET MET L . n 
D 4 48  ILE 48  48  48  ILE ILE L . n 
D 4 49  TYR 49  49  49  TYR TYR L . n 
D 4 50  ASP 50  50  50  ASP ASP L . n 
D 4 51  VAL 51  51  51  VAL VAL L . n 
D 4 52  THR 52  52  52  THR THR L . n 
D 4 53  GLN 53  53  53  GLN GLN L . n 
D 4 54  ARG 54  54  54  ARG ARG L . n 
D 4 55  PRO 55  55  55  PRO PRO L . n 
D 4 56  SER 56  56  56  SER SER L . n 
D 4 57  GLY 57  57  57  GLY GLY L . n 
D 4 58  VAL 58  58  58  VAL VAL L . n 
D 4 59  SER 59  59  59  SER SER L . n 
D 4 60  ASP 60  60  60  ASP ASP L . n 
D 4 61  ARG 61  61  61  ARG ARG L . n 
D 4 62  PHE 62  62  62  PHE PHE L . n 
D 4 63  SER 63  63  63  SER SER L . n 
D 4 64  GLY 64  64  64  GLY GLY L . n 
D 4 65  SER 65  65  65  SER SER L . n 
D 4 66  LYS 66  66  66  LYS LYS L . n 
D 4 67  SER 67  67  67  SER SER L . n 
D 4 68  GLY 68  68  68  GLY GLY L . n 
D 4 69  ASN 69  69  69  ASN ASN L . n 
D 4 70  THR 70  70  70  THR THR L . n 
D 4 71  ALA 71  71  71  ALA ALA L . n 
D 4 72  SER 72  72  72  SER SER L . n 
D 4 73  LEU 73  73  73  LEU LEU L . n 
D 4 74  THR 74  74  74  THR THR L . n 
D 4 75  ILE 75  75  75  ILE ILE L . n 
D 4 76  SER 76  76  76  SER SER L . n 
D 4 77  GLY 77  77  77  GLY GLY L . n 
D 4 78  LEU 78  78  78  LEU LEU L . n 
D 4 79  GLN 79  79  79  GLN GLN L . n 
D 4 80  ALA 80  80  80  ALA ALA L . n 
D 4 81  ASP 81  81  81  ASP ASP L . n 
D 4 82  ASP 82  82  82  ASP ASP L . n 
D 4 83  GLU 83  83  83  GLU GLU L . n 
D 4 84  ALA 84  84  84  ALA ALA L . n 
D 4 85  ASP 85  85  85  ASP ASP L . n 
D 4 86  TYR 86  86  86  TYR TYR L . n 
D 4 87  TYR 87  87  87  TYR TYR L . n 
D 4 88  CYS 88  88  88  CYS CYS L . n 
D 4 89  SER 89  89  89  SER SER L . n 
D 4 90  ALA 90  90  90  ALA ALA L . n 
D 4 91  TYR 91  91  91  TYR TYR L . n 
D 4 92  ALA 92  92  92  ALA ALA L . n 
D 4 93  GLY 93  93  93  GLY GLY L . n 
D 4 94  ARG 94  94  94  ARG ARG L . n 
D 4 95  GLN 95  95  95  GLN GLN L . n 
D 4 96  THR 96  95  95  THR THR L A n 
D 4 97  PHE 97  95  95  PHE PHE L B n 
D 4 98  TYR 98  96  96  TYR TYR L . n 
D 4 99  ILE 99  97  97  ILE ILE L . n 
D 4 100 PHE 100 98  98  PHE PHE L . n 
D 4 101 GLY 101 99  99  GLY GLY L . n 
D 4 102 GLY 102 100 100 GLY GLY L . n 
D 4 103 GLY 103 101 101 GLY GLY L . n 
D 4 104 THR 104 102 102 THR THR L . n 
D 4 105 ARG 105 103 103 ARG ARG L . n 
D 4 106 LEU 106 104 104 LEU LEU L . n 
D 4 107 THR 107 105 105 THR THR L . n 
D 4 108 VAL 108 106 106 VAL VAL L . n 
D 4 109 LEU 109 107 107 LEU LEU L . n 
D 4 110 GLY 110 108 ?   ?   ?   L . n 
D 4 111 GLN 111 109 ?   ?   ?   L . n 
D 4 112 PRO 112 110 ?   ?   ?   L . n 
D 4 113 LYS 113 111 ?   ?   ?   L . n 
D 4 114 ALA 114 112 ?   ?   ?   L . n 
D 4 115 SER 115 113 ?   ?   ?   L . n 
D 4 116 PRO 116 114 ?   ?   ?   L . n 
D 4 117 THR 117 115 ?   ?   ?   L . n 
D 4 118 VAL 118 116 ?   ?   ?   L . n 
D 4 119 THR 119 117 ?   ?   ?   L . n 
D 4 120 LEU 120 118 ?   ?   ?   L . n 
D 4 121 PHE 121 119 ?   ?   ?   L . n 
D 4 122 PRO 122 120 ?   ?   ?   L . n 
D 4 123 PRO 123 121 ?   ?   ?   L . n 
D 4 124 SER 124 122 ?   ?   ?   L . n 
D 4 125 SER 125 123 ?   ?   ?   L . n 
D 4 126 GLU 126 124 ?   ?   ?   L . n 
D 4 127 GLU 127 125 ?   ?   ?   L . n 
D 4 128 LEU 128 126 ?   ?   ?   L . n 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 andrew@scripps.edu Andrew  Ward   B. 'principal investigator/group leader' 0000-0001-7153-3769 
4 schief@scripps.edu William Schief ?  'principal investigator/group leader' 0000-0002-1120-0150 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
K 8 NAG 1 601 1046 NAG NAG A . 
L 8 NAG 1 602 1047 NAG NAG A . 
M 8 NAG 1 603 1048 NAG NAG A . 
N 8 NAG 1 604 1049 NAG NAG A . 
O 8 NAG 1 605 1050 NAG NAG A . 
P 8 NAG 1 606 1051 NAG NAG A . 
Q 8 NAG 1 607 1054 NAG NAG A . 
R 8 NAG 1 608 1055 NAG NAG A . 
S 8 NAG 1 609 1058 NAG NAG A . 
T 8 NAG 1 610 1059 NAG NAG A . 
U 8 NAG 1 611 1064 NAG NAG A . 
V 8 NAG 1 612 1065 NAG NAG A . 
W 8 NAG 1 613 1066 NAG NAG A . 
X 8 NAG 1 701 665  NAG NAG B . 
Y 8 NAG 1 702 666  NAG NAG B . 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete point assembly'                ? dodecameric 12 
2 'point asymmetric unit'                  ? tetrameric  4  
3 'point asymmetric unit, std point frame' ? tetrameric  4  
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-3)' A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y 
2 1       A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y 
3 P       A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P 'transform to point frame' ?     ?     -0.31598633 0.94876365  0.00042701 -114.12102 -0.94876354 -0.31598652 0.00050602  
227.89757 0.00061502 -0.00024523 0.99999978 -173.27549 
1 'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000 0.00000    0.00000000  1.00000000  0.00000000  0.00000 
0.00000000 0.00000000  1.00000000 0.00000    
2 'point symmetry operation' ?     ?     -0.49999943 -0.86602544 0.00071015 426.37292  0.86602498  -0.49999991 -0.00090048 
114.40632 0.00113491 0.00016478  0.99999934 -0.23417   
3 'point symmetry operation' ?     ?     -0.49999944 0.86602499  0.00113491 114.10775  -0.86602544 -0.49999991 0.00016477  
426.45298 0.00071015 -0.00090047 0.99999934 0.03440    
# 
_pdbx_point_symmetry.entry_id             7T75 
_pdbx_point_symmetry.Schoenflies_symbol   C 
_pdbx_point_symmetry.circular_symmetry    3 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2022-09-28 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_entry_details.entry_id                 7T75 
_pdbx_entry_details.has_ligand_of_interest   N 
_pdbx_entry_details.compound_details         ? 
_pdbx_entry_details.source_details           ? 
_pdbx_entry_details.nonpolymer_details       ? 
_pdbx_entry_details.sequence_details         ? 
# 
_em_3d_fitting.entry_id          7T75 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7T75 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               229356 
_em_3d_reconstruction.resolution                  2.7 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.details              ? 
_em_entity_assembly.name                 'HIV-1 Envelope ApexGT2 in complex with RM20A3 Fab' 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7T75 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             ? 
_em_imaging.nominal_defocus_min             ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7T75 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7T75 
_em_experiment.id                      1 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              7T75 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C3 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CG H TYR 100 G ? CD2 H TYR 100 G ? 1.301 1.387 -0.086 0.013 N 
2 1 CB L ASP 27  B ? CG  L ASP 27  B ? 1.355 1.513 -0.158 0.021 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE A ARG 143 ? ? CZ A ARG 143 ? ? NH2 A ARG 143 ? ? 116.18 120.30 -4.12 0.50 N 
2 1 CB A CYS 196 ? ? CA A CYS 196 ? ? C   A CYS 196 ? ? 118.84 111.50 7.34  1.20 N 
3 1 CB A TYR 217 ? ? CG A TYR 217 ? ? CD1 A TYR 217 ? ? 116.53 121.00 -4.47 0.60 N 
4 1 NE A ARG 456 ? ? CZ A ARG 456 ? ? NH2 A ARG 456 ? ? 116.37 120.30 -3.93 0.50 N 
5 1 NE A ARG 469 ? ? CZ A ARG 469 ? ? NH2 A ARG 469 ? ? 116.91 120.30 -3.39 0.50 N 
6 1 NE A ARG 476 ? ? CZ A ARG 476 ? ? NH2 A ARG 476 ? ? 116.52 120.30 -3.78 0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 94  ? ? -150.26 86.32   
2  1 TRP A 96  ? ? 87.00   -20.96  
3  1 THR A 257 ? ? -95.31  -98.49  
4  1 PHE A 391 ? ? -116.56 64.94   
5  1 MET A 426 ? ? 50.13   -68.53  
6  1 THR A 465 ? ? 92.59   114.32  
7  1 ASN B 625 ? ? -128.20 -121.90 
8  1 MET B 626 ? ? -0.21   86.42   
9  1 THR B 627 ? ? -34.62  167.31  
10 1 SER H 82  B ? 73.43   -4.66   
11 1 LEU H 82  C ? 7.92    96.25   
12 1 ALA H 100 ? ? 72.84   -35.10  
13 1 LYS H 100 E ? -111.12 -93.47  
14 1 ASP L 27  B ? -163.80 -108.69 
15 1 VAL L 51  ? ? 70.21   -57.21  
16 1 SER L 76  ? ? -89.69  -89.87  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 0   ? A MET 1   
2   1 Y 1 A GLY 1   ? A GLY 2   
3   1 Y 1 A ILE 2   ? A ILE 3   
4   1 Y 1 A LEU 3   ? A LEU 4   
5   1 Y 1 A PRO 4   ? A PRO 5   
6   1 Y 1 A SER 5   ? A SER 6   
7   1 Y 1 A PRO 6   ? A PRO 7   
8   1 Y 1 A GLY 7   ? A GLY 8   
9   1 Y 1 A MET 8   ? A MET 9   
10  1 Y 1 A PRO 9   ? A PRO 10  
11  1 Y 1 A ALA 10  ? A ALA 11  
12  1 Y 1 A LEU 11  ? A LEU 12  
13  1 Y 1 A LEU 12  ? A LEU 13  
14  1 Y 1 A SER 13  ? A SER 14  
15  1 Y 1 A LEU 14  ? A LEU 15  
16  1 Y 1 A VAL 15  ? A VAL 16  
17  1 Y 1 A SER 16  ? A SER 17  
18  1 Y 1 A LEU 17  ? A LEU 18  
19  1 Y 1 A LEU 18  ? A LEU 19  
20  1 Y 1 A SER 19  ? A SER 20  
21  1 Y 1 A VAL 20  ? A VAL 21  
22  1 Y 1 A LEU 21  ? A LEU 22  
23  1 Y 1 A LEU 22  ? A LEU 23  
24  1 Y 1 A MET 23  ? A MET 24  
25  1 Y 1 A GLY 24  ? A GLY 25  
26  1 Y 1 A CYS 25  ? A CYS 26  
27  1 Y 1 A VAL 26  ? A VAL 27  
28  1 Y 1 A ALA 27  ? A ALA 28  
29  1 Y 1 A GLU 28  ? A GLU 29  
30  1 Y 1 A THR 29  ? A THR 30  
31  1 Y 1 A GLY 30  ? A GLY 31  
32  1 Y 1 A ALA 31  ? A ALA 32  
33  1 Y 1 A GLU 32  ? A GLU 33  
34  1 Y 1 A ALA 58  ? A ALA 59  
35  1 Y 1 A LYS 59  ? A LYS 60  
36  1 Y 1 A ALA 60  ? A ALA 61  
37  1 Y 1 A TYR 61  ? A TYR 62  
38  1 Y 1 A GLU 62  ? A GLU 63  
39  1 Y 1 A THR 63  ? A THR 64  
40  1 Y 1 A GLU 64  ? A GLU 65  
41  1 Y 1 A LYS 65  ? A LYS 66  
42  1 Y 1 A HIS 66  ? A HIS 67  
43  1 Y 1 A ASN 67  ? A ASN 68  
44  1 Y 1 A VAL 68  ? A VAL 69  
45  1 Y 1 A TRP 69  ? A TRP 70  
46  1 Y 1 A ALA 70  ? A ALA 71  
47  1 Y 1 A THR 71  ? A THR 72  
48  1 Y 1 A HIS 72  ? A HIS 73  
49  1 Y 1 A ALA 73  ? A ALA 74  
50  1 Y 1 A CYS 74  ? A CYS 75  
51  1 Y 1 A VAL 75  ? A VAL 76  
52  1 Y 1 A PRO 76  ? A PRO 77  
53  1 Y 1 A THR 77  ? A THR 78  
54  1 Y 1 A ASP 78  ? A ASP 79  
55  1 Y 1 A PRO 79  ? A PRO 80  
56  1 Y 1 A ASN 80  ? A ASN 81  
57  1 Y 1 A PRO 81  ? A PRO 82  
58  1 Y 1 A ASN 397 A A ASN 390 
59  1 Y 1 A THR 397 B A THR 391 
60  1 Y 1 A SER 397 C A SER 392 
61  1 Y 1 A VAL 397 D A VAL 393 
62  1 Y 1 A GLN 397 E A GLN 394 
63  1 Y 1 A GLY 397 F A GLY 395 
64  1 Y 1 A SER 397 G A SER 396 
65  1 Y 1 A ASN 397 H A ASN 397 
66  1 Y 1 A SER 397 I A SER 398 
67  1 Y 1 A THR 397 J A THR 399 
68  1 Y 1 A GLY 397 K A GLY 400 
69  1 Y 1 A SER 397 L A SER 401 
70  1 Y 1 A GLY 458 ? A GLY 449 
71  1 Y 1 A GLY 459 ? A GLY 450 
72  1 Y 1 A SER 460 ? A SER 451 
73  1 Y 1 A THR 461 ? A THR 452 
74  1 Y 1 A ASN 462 ? A ASN 453 
75  1 Y 1 A SER 463 ? A SER 454 
76  1 Y 1 A ARG 504 ? A ARG 495 
77  1 Y 1 A VAL 505 ? A VAL 496 
78  1 Y 1 A VAL 506 ? A VAL 497 
79  1 Y 1 A GLY 507 ? A GLY 498 
80  1 Y 1 A ARG 508 ? A ARG 499 
81  1 Y 1 A ARG 509 ? A ARG 500 
82  1 Y 1 A ARG 510 ? A ARG 501 
83  1 Y 1 A ARG 511 ? A ARG 502 
84  1 Y 1 A ARG 512 ? A ARG 503 
85  1 Y 1 A ARG 513 ? A ARG 504 
86  1 Y 1 B ALA 510 ? B ALA 1   
87  1 Y 1 B VAL 511 ? B VAL 2   
88  1 Y 1 B GLY 512 ? B GLY 3   
89  1 Y 1 B ILE 513 ? B ILE 4   
90  1 Y 1 B GLY 514 ? B GLY 5   
91  1 Y 1 B ALA 515 ? B ALA 6   
92  1 Y 1 B VAL 516 ? B VAL 7   
93  1 Y 1 B SER 517 ? B SER 8   
94  1 Y 1 B GLY 547 ? B GLY 36  
95  1 Y 1 B ILE 548 ? B ILE 37  
96  1 Y 1 B VAL 549 ? B VAL 38  
97  1 Y 1 B GLN 550 ? B GLN 39  
98  1 Y 1 B GLN 551 ? B GLN 40  
99  1 Y 1 B GLN 552 ? B GLN 41  
100 1 Y 1 B SER 553 ? B SER 42  
101 1 Y 1 B ASN 554 ? B ASN 43  
102 1 Y 1 B LEU 555 ? B LEU 44  
103 1 Y 1 B LEU 556 ? B LEU 45  
104 1 Y 1 B ARG 557 ? B ARG 46  
105 1 Y 1 B ALA 558 ? B ALA 47  
106 1 Y 1 B PRO 559 ? B PRO 48  
107 1 Y 1 B GLU 560 ? B GLU 49  
108 1 Y 1 B PRO 561 ? B PRO 50  
109 1 Y 1 B GLN 562 ? B GLN 51  
110 1 Y 1 B GLN 563 ? B GLN 52  
111 1 Y 1 B HIS 564 ? B HIS 53  
112 1 Y 1 B LEU 565 ? B LEU 54  
113 1 Y 1 B LEU 566 ? B LEU 55  
114 1 Y 1 B LYS 567 ? B LYS 56  
115 1 Y 1 B ASP 568 ? B ASP 57  
116 1 Y 1 B THR 569 ? B THR 58  
117 1 Y 1 B LEU 663 ? B LEU 152 
118 1 Y 1 B ASP 664 ? B ASP 153 
119 1 Y 1 B GLY 665 ? B GLY 154 
120 1 Y 1 B THR 666 ? B THR 155 
121 1 Y 1 B LYS 667 ? B LYS 156 
122 1 Y 1 B HIS 668 ? B HIS 157 
123 1 Y 1 B HIS 669 ? B HIS 158 
124 1 Y 1 B HIS 670 ? B HIS 159 
125 1 Y 1 B HIS 671 ? B HIS 160 
126 1 Y 1 B HIS 672 ? B HIS 161 
127 1 Y 1 B HIS 673 ? B HIS 162 
128 1 Y 1 H SER 113 ? C SER 125 
129 1 Y 1 L GLY 108 ? D GLY 110 
130 1 Y 1 L GLN 109 ? D GLN 111 
131 1 Y 1 L PRO 110 ? D PRO 112 
132 1 Y 1 L LYS 111 ? D LYS 113 
133 1 Y 1 L ALA 112 ? D ALA 114 
134 1 Y 1 L SER 113 ? D SER 115 
135 1 Y 1 L PRO 114 ? D PRO 116 
136 1 Y 1 L THR 115 ? D THR 117 
137 1 Y 1 L VAL 116 ? D VAL 118 
138 1 Y 1 L THR 117 ? D THR 119 
139 1 Y 1 L LEU 118 ? D LEU 120 
140 1 Y 1 L PHE 119 ? D PHE 121 
141 1 Y 1 L PRO 120 ? D PRO 122 
142 1 Y 1 L PRO 121 ? D PRO 123 
143 1 Y 1 L SER 122 ? D SER 124 
144 1 Y 1 L SER 123 ? D SER 125 
145 1 Y 1 L GLU 124 ? D GLU 126 
146 1 Y 1 L GLU 125 ? D GLU 127 
147 1 Y 1 L LEU 126 ? D LEU 128 
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.ncbi_tax_id          11676 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organism             'Human immunodeficiency virus 1' 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.cell                 HEK 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'CRYSTALLOGRAPHY MERGING'  ? ? ? 1 ? 1 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Bill & Melinda Gates Foundation'                                                                 'United States' OPP1084519     1 
'Bill & Melinda Gates Foundation'                                                                 'United States' OPP1196345     2 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'UM1 Al100663' 3 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'UM1 AI144462' 4 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
E 5 NAG 1 C NAG 1 A NAG 1052 n 
E 5 NAG 2 C NAG 2 A NAG 1053 n 
F 5 NAG 1 D NAG 1 A NAG 1056 n 
F 5 NAG 2 D NAG 2 A NAG 1057 n 
G 6 NAG 1 E NAG 1 A NAG 1060 n 
G 6 NAG 2 E NAG 2 A NAG 1061 n 
G 6 BMA 3 E BMA 3 A BMA 1062 n 
G 6 MAN 4 E MAN 4 A MAN 1063 n 
H 5 NAG 1 F NAG 1 A NAG 1067 n 
H 5 NAG 2 F NAG 2 A NAG 1068 n 
I 7 NAG 1 G NAG 1 B NAG 663  n 
I 7 FUC 2 G FUC 2 B FUC 664  n 
J 7 NAG 1 I NAG 1 B NAG 667  n 
J 7 FUC 2 I FUC 2 B FUC 668  n 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa                         
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose               
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp                       
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
5 oligosaccharide 
6 oligosaccharide 
7 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 5 DGlcpNAcb1-4DGlcpNAcb1-ROH                                                                          
'Glycam Condensed Sequence' GMML       1.0   
2 5 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                               WURCS PDB2Glycan 1.1.0 
3 5 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'                                                     LINUCS PDB-CARE   ?     
4 6 DManpa1-3DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH                                                        
'Glycam Condensed Sequence' GMML       1.0   
5 6 'WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3/a4-b1_b4-c1_c3-d1' WURCS PDB2Glycan 1.1.0 
6 6 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}}}}'               LINUCS PDB-CARE   ?     
7 7 LFucpa1-6DGlcpNAcb1-ROH                                                                             
'Glycam Condensed Sequence' GMML       1.0   
8 7 'WURCS=2.0/2,2,1/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5]/1-2/a6-b1'                                WURCS PDB2Glycan 1.1.0 
9 7 '[][D-1-deoxy-GlcpNAc]{[(6+1)][a-L-Fucp]{}}'                                                        LINUCS PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 5 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 6 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
3 6 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
4 6 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
5 7 2 FUC C1 O1 1 NAG O6 HO6 sing ? 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
5 NAG 1 n 
5 NAG 2 n 
6 NAG 1 n 
6 NAG 2 n 
6 BMA 3 n 
6 MAN 4 n 
7 NAG 1 n 
7 FUC 2 n 
# 
_pdbx_entity_nonpoly.entity_id   8 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
