data_7X37
# 
_entry.id   7X37 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.360 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7X37         pdb_00007x37 10.2210/pdb7x37/pdb 
WWPDB D_1300027908 ?            ?                   
EMDB  EMD-32980    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Coxsackievirus B1 A particle in complex with nAb 2E6 (CVB1-A:2E6)' 
_pdbx_database_related.db_id          EMD-32980 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7X37 
_pdbx_database_status.recvd_initial_deposition_date   2022-02-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zheng, Q.' 1 ? 
'Zhu, R.'   2 ? 
'Sun, H.'   3 ? 
'Cheng, T.' 4 ? 
'Li, S.'    5 ? 
'Xia, N.'   6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Host Microbe' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1934-6069 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.' 
_citation.year                      2022 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.chom.2022.08.001 
_citation.pdbx_database_id_PubMed   36002016 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zheng, Q.' 1  ? 
primary 'Zhu, R.'   2  ? 
primary 'Yin, Z.'   3  ? 
primary 'Xu, L.'    4  ? 
primary 'Sun, H.'   5  ? 
primary 'Yu, H.'    6  ? 
primary 'Wu, Y.'    7  ? 
primary 'Jiang, Y.' 8  ? 
primary 'Huang, Q.' 9  ? 
primary 'Huang, Y.' 10 ? 
primary 'Zhang, D.' 11 ? 
primary 'Liu, L.'   12 ? 
primary 'Yang, H.'  13 ? 
primary 'He, M.'    14 ? 
primary 'Zhou, Z.'  15 ? 
primary 'Jiang, Y.' 16 ? 
primary 'Chen, Z.'  17 ? 
primary 'Zhao, H.'  18 ? 
primary 'Que, Y.'   19 ? 
primary 'Kong, Z.'  20 ? 
primary 'Zhou, L.'  21 ? 
primary 'Li, T.'    22 ? 
primary 'Zhang, J.' 23 ? 
primary 'Luo, W.'   24 ? 
primary 'Gu, Y.'    25 ? 
primary 'Cheng, T.' 26 ? 
primary 'Li, S.'    27 ? 
primary 'Xia, N.'   28 ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7X37 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         7X37 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer nat '2E6 light chain'  11720.020 1 ?                                     ? ? ? 
2 polymer nat '2E6 heavy chain'  13091.568 1 ?                                     ? ? ? 
3 polymer nat 'Virion protein 1' 31207.117 1 ?                                     ? ? ? 
4 polymer nat VP2                29122.744 1 ?                                     ? ? ? 
5 polymer nat VP3                26328.764 1 3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48 ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'VP1, P1C,P1D' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DIQMTQSPASLSVSVGETVTITCRASENVYRNLAWYQQKQGKSPQLLVYAATNLADGVPSRFSGSGSGTQYSLKINSLQS
EDFGSYFCQHFWSPVFTFGAGTKLELK
;
;DIQMTQSPASLSVSVGETVTITCRASENVYRNLAWYQQKQGKSPQLLVYAATNLADGVPSRFSGSGSGTQYSLKINSLQS
EDFGSYFCQHFWSPVFTFGAGTKLELK
;
L ? 
2 'polypeptide(L)' no no 
;QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWRGGSTDYNAAFMSRLSITKDNSKSQVFF
KMNSLQADDTAIYYCAKGDYYGYDAMDSWGQGTSVTVSR
;
;QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWRGGSTDYNAAFMSRLSITKDNSKSQVFF
KMNSLQADDTAIYYCAKGDYYGYDAMDSWGQGTSVTVSR
;
H ? 
3 'polypeptide(L)' no no 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
A ? 
4 'polypeptide(L)' no no 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
B ? 
5 'polypeptide(L)' no no 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   ILE n 
1 3   GLN n 
1 4   MET n 
1 5   THR n 
1 6   GLN n 
1 7   SER n 
1 8   PRO n 
1 9   ALA n 
1 10  SER n 
1 11  LEU n 
1 12  SER n 
1 13  VAL n 
1 14  SER n 
1 15  VAL n 
1 16  GLY n 
1 17  GLU n 
1 18  THR n 
1 19  VAL n 
1 20  THR n 
1 21  ILE n 
1 22  THR n 
1 23  CYS n 
1 24  ARG n 
1 25  ALA n 
1 26  SER n 
1 27  GLU n 
1 28  ASN n 
1 29  VAL n 
1 30  TYR n 
1 31  ARG n 
1 32  ASN n 
1 33  LEU n 
1 34  ALA n 
1 35  TRP n 
1 36  TYR n 
1 37  GLN n 
1 38  GLN n 
1 39  LYS n 
1 40  GLN n 
1 41  GLY n 
1 42  LYS n 
1 43  SER n 
1 44  PRO n 
1 45  GLN n 
1 46  LEU n 
1 47  LEU n 
1 48  VAL n 
1 49  TYR n 
1 50  ALA n 
1 51  ALA n 
1 52  THR n 
1 53  ASN n 
1 54  LEU n 
1 55  ALA n 
1 56  ASP n 
1 57  GLY n 
1 58  VAL n 
1 59  PRO n 
1 60  SER n 
1 61  ARG n 
1 62  PHE n 
1 63  SER n 
1 64  GLY n 
1 65  SER n 
1 66  GLY n 
1 67  SER n 
1 68  GLY n 
1 69  THR n 
1 70  GLN n 
1 71  TYR n 
1 72  SER n 
1 73  LEU n 
1 74  LYS n 
1 75  ILE n 
1 76  ASN n 
1 77  SER n 
1 78  LEU n 
1 79  GLN n 
1 80  SER n 
1 81  GLU n 
1 82  ASP n 
1 83  PHE n 
1 84  GLY n 
1 85  SER n 
1 86  TYR n 
1 87  PHE n 
1 88  CYS n 
1 89  GLN n 
1 90  HIS n 
1 91  PHE n 
1 92  TRP n 
1 93  SER n 
1 94  PRO n 
1 95  VAL n 
1 96  PHE n 
1 97  THR n 
1 98  PHE n 
1 99  GLY n 
1 100 ALA n 
1 101 GLY n 
1 102 THR n 
1 103 LYS n 
1 104 LEU n 
1 105 GLU n 
1 106 LEU n 
1 107 LYS n 
2 1   GLN n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   LYS n 
2 6   GLN n 
2 7   SER n 
2 8   GLY n 
2 9   PRO n 
2 10  GLY n 
2 11  LEU n 
2 12  VAL n 
2 13  GLN n 
2 14  PRO n 
2 15  SER n 
2 16  GLN n 
2 17  SER n 
2 18  LEU n 
2 19  SER n 
2 20  ILE n 
2 21  THR n 
2 22  CYS n 
2 23  THR n 
2 24  VAL n 
2 25  SER n 
2 26  GLY n 
2 27  PHE n 
2 28  SER n 
2 29  LEU n 
2 30  THR n 
2 31  ASN n 
2 32  TYR n 
2 33  GLY n 
2 34  VAL n 
2 35  HIS n 
2 36  TRP n 
2 37  VAL n 
2 38  ARG n 
2 39  GLN n 
2 40  SER n 
2 41  PRO n 
2 42  GLY n 
2 43  LYS n 
2 44  GLY n 
2 45  LEU n 
2 46  GLU n 
2 47  TRP n 
2 48  LEU n 
2 49  GLY n 
2 50  VAL n 
2 51  ILE n 
2 52  TRP n 
2 53  ARG n 
2 54  GLY n 
2 55  GLY n 
2 56  SER n 
2 57  THR n 
2 58  ASP n 
2 59  TYR n 
2 60  ASN n 
2 61  ALA n 
2 62  ALA n 
2 63  PHE n 
2 64  MET n 
2 65  SER n 
2 66  ARG n 
2 67  LEU n 
2 68  SER n 
2 69  ILE n 
2 70  THR n 
2 71  LYS n 
2 72  ASP n 
2 73  ASN n 
2 74  SER n 
2 75  LYS n 
2 76  SER n 
2 77  GLN n 
2 78  VAL n 
2 79  PHE n 
2 80  PHE n 
2 81  LYS n 
2 82  MET n 
2 83  ASN n 
2 84  SER n 
2 85  LEU n 
2 86  GLN n 
2 87  ALA n 
2 88  ASP n 
2 89  ASP n 
2 90  THR n 
2 91  ALA n 
2 92  ILE n 
2 93  TYR n 
2 94  TYR n 
2 95  CYS n 
2 96  ALA n 
2 97  LYS n 
2 98  GLY n 
2 99  ASP n 
2 100 TYR n 
2 101 TYR n 
2 102 GLY n 
2 103 TYR n 
2 104 ASP n 
2 105 ALA n 
2 106 MET n 
2 107 ASP n 
2 108 SER n 
2 109 TRP n 
2 110 GLY n 
2 111 GLN n 
2 112 GLY n 
2 113 THR n 
2 114 SER n 
2 115 VAL n 
2 116 THR n 
2 117 VAL n 
2 118 SER n 
2 119 ARG n 
3 1   GLY n 
3 2   PRO n 
3 3   VAL n 
3 4   GLU n 
3 5   GLU n 
3 6   SER n 
3 7   VAL n 
3 8   ASP n 
3 9   ARG n 
3 10  ALA n 
3 11  VAL n 
3 12  ALA n 
3 13  ARG n 
3 14  VAL n 
3 15  ALA n 
3 16  ASP n 
3 17  THR n 
3 18  ILE n 
3 19  SER n 
3 20  SER n 
3 21  ARG n 
3 22  PRO n 
3 23  THR n 
3 24  ASN n 
3 25  SER n 
3 26  GLU n 
3 27  SER n 
3 28  ILE n 
3 29  PRO n 
3 30  ALA n 
3 31  LEU n 
3 32  THR n 
3 33  ALA n 
3 34  ALA n 
3 35  GLU n 
3 36  THR n 
3 37  GLY n 
3 38  HIS n 
3 39  THR n 
3 40  SER n 
3 41  GLN n 
3 42  VAL n 
3 43  VAL n 
3 44  PRO n 
3 45  SER n 
3 46  ASP n 
3 47  THR n 
3 48  MET n 
3 49  GLN n 
3 50  THR n 
3 51  ARG n 
3 52  HIS n 
3 53  VAL n 
3 54  LYS n 
3 55  ASN n 
3 56  TYR n 
3 57  HIS n 
3 58  SER n 
3 59  ARG n 
3 60  SER n 
3 61  GLU n 
3 62  SER n 
3 63  SER n 
3 64  ILE n 
3 65  GLU n 
3 66  ASN n 
3 67  PHE n 
3 68  LEU n 
3 69  CYS n 
3 70  ARG n 
3 71  SER n 
3 72  ALA n 
3 73  CYS n 
3 74  VAL n 
3 75  TYR n 
3 76  TYR n 
3 77  ALA n 
3 78  THR n 
3 79  TYR n 
3 80  THR n 
3 81  ASN n 
3 82  ASN n 
3 83  SER n 
3 84  LYS n 
3 85  LYS n 
3 86  GLY n 
3 87  PHE n 
3 88  ALA n 
3 89  GLU n 
3 90  TRP n 
3 91  VAL n 
3 92  ILE n 
3 93  ASN n 
3 94  THR n 
3 95  ARG n 
3 96  GLN n 
3 97  VAL n 
3 98  ALA n 
3 99  GLN n 
3 100 LEU n 
3 101 ARG n 
3 102 ARG n 
3 103 LYS n 
3 104 LEU n 
3 105 GLU n 
3 106 LEU n 
3 107 PHE n 
3 108 THR n 
3 109 TYR n 
3 110 LEU n 
3 111 ARG n 
3 112 PHE n 
3 113 ASP n 
3 114 LEU n 
3 115 GLU n 
3 116 LEU n 
3 117 THR n 
3 118 PHE n 
3 119 VAL n 
3 120 ILE n 
3 121 THR n 
3 122 SER n 
3 123 ALA n 
3 124 GLN n 
3 125 GLN n 
3 126 PRO n 
3 127 SER n 
3 128 THR n 
3 129 ALA n 
3 130 SER n 
3 131 SER n 
3 132 VAL n 
3 133 ASP n 
3 134 ALA n 
3 135 PRO n 
3 136 VAL n 
3 137 GLN n 
3 138 THR n 
3 139 HIS n 
3 140 GLN n 
3 141 ILE n 
3 142 MET n 
3 143 TYR n 
3 144 VAL n 
3 145 PRO n 
3 146 PRO n 
3 147 GLY n 
3 148 GLY n 
3 149 PRO n 
3 150 VAL n 
3 151 PRO n 
3 152 THR n 
3 153 LYS n 
3 154 VAL n 
3 155 LYS n 
3 156 ASP n 
3 157 TYR n 
3 158 ALA n 
3 159 TRP n 
3 160 GLN n 
3 161 THR n 
3 162 SER n 
3 163 THR n 
3 164 ASN n 
3 165 PRO n 
3 166 SER n 
3 167 VAL n 
3 168 PHE n 
3 169 TRP n 
3 170 THR n 
3 171 GLU n 
3 172 GLY n 
3 173 ASN n 
3 174 ALA n 
3 175 PRO n 
3 176 PRO n 
3 177 ARG n 
3 178 MET n 
3 179 SER n 
3 180 ILE n 
3 181 PRO n 
3 182 PHE n 
3 183 ILE n 
3 184 SER n 
3 185 ILE n 
3 186 GLY n 
3 187 ASN n 
3 188 ALA n 
3 189 TYR n 
3 190 SER n 
3 191 CYS n 
3 192 PHE n 
3 193 TYR n 
3 194 ASP n 
3 195 GLY n 
3 196 TRP n 
3 197 THR n 
3 198 GLN n 
3 199 PHE n 
3 200 SER n 
3 201 ARG n 
3 202 ASN n 
3 203 GLY n 
3 204 VAL n 
3 205 TYR n 
3 206 GLY n 
3 207 ILE n 
3 208 ASN n 
3 209 THR n 
3 210 LEU n 
3 211 ASN n 
3 212 ASN n 
3 213 MET n 
3 214 GLY n 
3 215 THR n 
3 216 LEU n 
3 217 TYR n 
3 218 MET n 
3 219 ARG n 
3 220 HIS n 
3 221 VAL n 
3 222 ASN n 
3 223 GLU n 
3 224 ALA n 
3 225 GLY n 
3 226 GLN n 
3 227 GLY n 
3 228 PRO n 
3 229 ILE n 
3 230 LYS n 
3 231 SER n 
3 232 THR n 
3 233 VAL n 
3 234 ARG n 
3 235 ILE n 
3 236 TYR n 
3 237 PHE n 
3 238 LYS n 
3 239 PRO n 
3 240 LYS n 
3 241 HIS n 
3 242 VAL n 
3 243 LYS n 
3 244 ALA n 
3 245 TRP n 
3 246 VAL n 
3 247 PRO n 
3 248 ARG n 
3 249 PRO n 
3 250 PRO n 
3 251 ARG n 
3 252 LEU n 
3 253 CYS n 
3 254 GLN n 
3 255 TYR n 
3 256 GLU n 
3 257 LYS n 
3 258 GLN n 
3 259 LYS n 
3 260 ASN n 
3 261 VAL n 
3 262 ASN n 
3 263 PHE n 
3 264 SER n 
3 265 PRO n 
3 266 ILE n 
3 267 GLY n 
3 268 VAL n 
3 269 THR n 
3 270 THR n 
3 271 SER n 
3 272 ARG n 
3 273 THR n 
3 274 ASP n 
3 275 ILE n 
3 276 ILE n 
3 277 THR n 
3 278 THR n 
4 1   SER n 
4 2   PRO n 
4 3   SER n 
4 4   ALA n 
4 5   GLU n 
4 6   GLU n 
4 7   CYS n 
4 8   GLY n 
4 9   TYR n 
4 10  SER n 
4 11  ASP n 
4 12  ARG n 
4 13  VAL n 
4 14  ARG n 
4 15  SER n 
4 16  ILE n 
4 17  THR n 
4 18  LEU n 
4 19  GLY n 
4 20  ASN n 
4 21  SER n 
4 22  THR n 
4 23  ILE n 
4 24  THR n 
4 25  THR n 
4 26  GLN n 
4 27  GLU n 
4 28  CYS n 
4 29  ALA n 
4 30  ASN n 
4 31  VAL n 
4 32  VAL n 
4 33  VAL n 
4 34  GLY n 
4 35  TYR n 
4 36  GLY n 
4 37  VAL n 
4 38  TRP n 
4 39  PRO n 
4 40  GLU n 
4 41  TYR n 
4 42  LEU n 
4 43  LYS n 
4 44  ASP n 
4 45  ASN n 
4 46  GLU n 
4 47  ALA n 
4 48  THR n 
4 49  ALA n 
4 50  GLU n 
4 51  ASP n 
4 52  GLN n 
4 53  PRO n 
4 54  THR n 
4 55  GLN n 
4 56  PRO n 
4 57  ASP n 
4 58  VAL n 
4 59  ALA n 
4 60  THR n 
4 61  CYS n 
4 62  ARG n 
4 63  PHE n 
4 64  TYR n 
4 65  THR n 
4 66  LEU n 
4 67  GLU n 
4 68  SER n 
4 69  VAL n 
4 70  GLN n 
4 71  TRP n 
4 72  MET n 
4 73  LYS n 
4 74  ASN n 
4 75  SER n 
4 76  ALA n 
4 77  GLY n 
4 78  TRP n 
4 79  TRP n 
4 80  TRP n 
4 81  LYS n 
4 82  LEU n 
4 83  PRO n 
4 84  ASP n 
4 85  ALA n 
4 86  LEU n 
4 87  SER n 
4 88  GLN n 
4 89  MET n 
4 90  GLY n 
4 91  LEU n 
4 92  PHE n 
4 93  GLY n 
4 94  GLN n 
4 95  ASN n 
4 96  MET n 
4 97  GLN n 
4 98  TYR n 
4 99  HIS n 
4 100 TYR n 
4 101 LEU n 
4 102 GLY n 
4 103 ARG n 
4 104 THR n 
4 105 GLY n 
4 106 TYR n 
4 107 THR n 
4 108 ILE n 
4 109 HIS n 
4 110 VAL n 
4 111 GLN n 
4 112 CYS n 
4 113 ASN n 
4 114 ALA n 
4 115 SER n 
4 116 LYS n 
4 117 PHE n 
4 118 HIS n 
4 119 GLN n 
4 120 GLY n 
4 121 CYS n 
4 122 LEU n 
4 123 LEU n 
4 124 VAL n 
4 125 VAL n 
4 126 CYS n 
4 127 VAL n 
4 128 PRO n 
4 129 GLU n 
4 130 ALA n 
4 131 GLU n 
4 132 MET n 
4 133 GLY n 
4 134 CYS n 
4 135 SER n 
4 136 ASN n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 THR n 
4 141 PRO n 
4 142 GLU n 
4 143 PHE n 
4 144 SER n 
4 145 GLU n 
4 146 LEU n 
4 147 SER n 
4 148 GLY n 
4 149 GLY n 
4 150 ASP n 
4 151 SER n 
4 152 ALA n 
4 153 ARG n 
4 154 MET n 
4 155 PHE n 
4 156 THR n 
4 157 ASP n 
4 158 THR n 
4 159 GLN n 
4 160 VAL n 
4 161 GLY n 
4 162 GLU n 
4 163 SER n 
4 164 ASN n 
4 165 ALA n 
4 166 LYS n 
4 167 LYS n 
4 168 VAL n 
4 169 GLN n 
4 170 THR n 
4 171 ALA n 
4 172 VAL n 
4 173 TRP n 
4 174 ASN n 
4 175 ALA n 
4 176 GLY n 
4 177 MET n 
4 178 GLY n 
4 179 VAL n 
4 180 GLY n 
4 181 VAL n 
4 182 GLY n 
4 183 ASN n 
4 184 LEU n 
4 185 THR n 
4 186 ILE n 
4 187 PHE n 
4 188 PRO n 
4 189 HIS n 
4 190 GLN n 
4 191 TRP n 
4 192 ILE n 
4 193 ASN n 
4 194 LEU n 
4 195 ARG n 
4 196 THR n 
4 197 ASN n 
4 198 ASN n 
4 199 SER n 
4 200 ALA n 
4 201 THR n 
4 202 LEU n 
4 203 VAL n 
4 204 MET n 
4 205 PRO n 
4 206 TYR n 
4 207 ILE n 
4 208 ASN n 
4 209 SER n 
4 210 VAL n 
4 211 PRO n 
4 212 MET n 
4 213 ASP n 
4 214 ASN n 
4 215 MET n 
4 216 PHE n 
4 217 ARG n 
4 218 HIS n 
4 219 ASN n 
4 220 ASN n 
4 221 LEU n 
4 222 THR n 
4 223 LEU n 
4 224 MET n 
4 225 ILE n 
4 226 ILE n 
4 227 PRO n 
4 228 PHE n 
4 229 VAL n 
4 230 PRO n 
4 231 LEU n 
4 232 ASN n 
4 233 TYR n 
4 234 SER n 
4 235 GLU n 
4 236 GLY n 
4 237 SER n 
4 238 SER n 
4 239 PRO n 
4 240 TYR n 
4 241 VAL n 
4 242 PRO n 
4 243 ILE n 
4 244 THR n 
4 245 VAL n 
4 246 THR n 
4 247 ILE n 
4 248 ALA n 
4 249 PRO n 
4 250 MET n 
4 251 CYS n 
4 252 ALA n 
4 253 GLU n 
4 254 TYR n 
4 255 ASN n 
4 256 GLY n 
4 257 LEU n 
4 258 ARG n 
4 259 LEU n 
4 260 ALA n 
4 261 SER n 
4 262 ASN n 
4 263 GLN n 
5 1   GLY n 
5 2   LEU n 
5 3   PRO n 
5 4   VAL n 
5 5   MET n 
5 6   THR n 
5 7   THR n 
5 8   PRO n 
5 9   GLY n 
5 10  SER n 
5 11  THR n 
5 12  GLN n 
5 13  PHE n 
5 14  LEU n 
5 15  THR n 
5 16  SER n 
5 17  ASP n 
5 18  ASP n 
5 19  PHE n 
5 20  GLN n 
5 21  SER n 
5 22  PRO n 
5 23  SER n 
5 24  ALA n 
5 25  MET n 
5 26  PRO n 
5 27  GLN n 
5 28  PHE n 
5 29  ASP n 
5 30  VAL n 
5 31  THR n 
5 32  PRO n 
5 33  GLU n 
5 34  MET n 
5 35  GLN n 
5 36  ILE n 
5 37  PRO n 
5 38  GLY n 
5 39  ARG n 
5 40  VAL n 
5 41  ASN n 
5 42  ASN n 
5 43  LEU n 
5 44  MET n 
5 45  GLU n 
5 46  ILE n 
5 47  ALA n 
5 48  GLU n 
5 49  VAL n 
5 50  ASP n 
5 51  SER n 
5 52  VAL n 
5 53  VAL n 
5 54  PRO n 
5 55  VAL n 
5 56  ASN n 
5 57  ASN n 
5 58  THR n 
5 59  GLU n 
5 60  ASP n 
5 61  ASN n 
5 62  VAL n 
5 63  SER n 
5 64  SER n 
5 65  LEU n 
5 66  LYS n 
5 67  ALA n 
5 68  TYR n 
5 69  GLN n 
5 70  ILE n 
5 71  PRO n 
5 72  VAL n 
5 73  GLN n 
5 74  SER n 
5 75  ASN n 
5 76  SER n 
5 77  ASP n 
5 78  ASN n 
5 79  GLY n 
5 80  LYS n 
5 81  GLN n 
5 82  VAL n 
5 83  PHE n 
5 84  GLY n 
5 85  PHE n 
5 86  PRO n 
5 87  LEU n 
5 88  GLN n 
5 89  PRO n 
5 90  GLY n 
5 91  ALA n 
5 92  ASN n 
5 93  ASN n 
5 94  VAL n 
5 95  LEU n 
5 96  ASN n 
5 97  ARG n 
5 98  THR n 
5 99  LEU n 
5 100 LEU n 
5 101 GLY n 
5 102 GLU n 
5 103 ILE n 
5 104 LEU n 
5 105 ASN n 
5 106 TYR n 
5 107 TYR n 
5 108 THR n 
5 109 HIS n 
5 110 TRP n 
5 111 SER n 
5 112 GLY n 
5 113 SER n 
5 114 ILE n 
5 115 LYS n 
5 116 LEU n 
5 117 THR n 
5 118 PHE n 
5 119 MET n 
5 120 PHE n 
5 121 CYS n 
5 122 GLY n 
5 123 SER n 
5 124 ALA n 
5 125 MET n 
5 126 ALA n 
5 127 THR n 
5 128 GLY n 
5 129 LYS n 
5 130 PHE n 
5 131 LEU n 
5 132 LEU n 
5 133 ALA n 
5 134 TYR n 
5 135 SER n 
5 136 PRO n 
5 137 PRO n 
5 138 GLY n 
5 139 ALA n 
5 140 GLY n 
5 141 VAL n 
5 142 PRO n 
5 143 LYS n 
5 144 ASN n 
5 145 ARG n 
5 146 LYS n 
5 147 ASP n 
5 148 ALA n 
5 149 MET n 
5 150 LEU n 
5 151 GLY n 
5 152 THR n 
5 153 HIS n 
5 154 VAL n 
5 155 ILE n 
5 156 TRP n 
5 157 ASP n 
5 158 VAL n 
5 159 GLY n 
5 160 LEU n 
5 161 GLN n 
5 162 SER n 
5 163 SER n 
5 164 CYS n 
5 165 VAL n 
5 166 LEU n 
5 167 CYS n 
5 168 VAL n 
5 169 PRO n 
5 170 TRP n 
5 171 ILE n 
5 172 SER n 
5 173 GLN n 
5 174 THR n 
5 175 HIS n 
5 176 TYR n 
5 177 ARG n 
5 178 TYR n 
5 179 VAL n 
5 180 VAL n 
5 181 GLU n 
5 182 ASP n 
5 183 GLU n 
5 184 TYR n 
5 185 THR n 
5 186 ALA n 
5 187 ALA n 
5 188 GLY n 
5 189 TYR n 
5 190 VAL n 
5 191 THR n 
5 192 CYS n 
5 193 TRP n 
5 194 TYR n 
5 195 GLN n 
5 196 THR n 
5 197 ASN n 
5 198 ILE n 
5 199 VAL n 
5 200 VAL n 
5 201 PRO n 
5 202 ALA n 
5 203 ASP n 
5 204 VAL n 
5 205 GLN n 
5 206 SER n 
5 207 SER n 
5 208 CYS n 
5 209 ASP n 
5 210 ILE n 
5 211 LEU n 
5 212 CYS n 
5 213 PHE n 
5 214 VAL n 
5 215 SER n 
5 216 ALA n 
5 217 CYS n 
5 218 ASN n 
5 219 ASP n 
5 220 PHE n 
5 221 SER n 
5 222 VAL n 
5 223 ARG n 
5 224 MET n 
5 225 LEU n 
5 226 LYS n 
5 227 ASP n 
5 228 THR n 
5 229 PRO n 
5 230 PHE n 
5 231 ILE n 
5 232 ARG n 
5 233 GLN n 
5 234 ASP n 
5 235 THR n 
5 236 PHE n 
5 237 TYR n 
5 238 GLN n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 107 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 119 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 1 278 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 263 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 1 238 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7X37             7X37       ? 1 ? 1   
2 PDB 7X37             7X37       ? 2 ? 1   
3 UNP W8GTF7_9ENTO     W8GTF7     ? 3 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSEKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
1   
4 UNP A0A2S0RQC2_9ENTO A0A2S0RQC2 ? 4 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
70  
5 UNP L7UV52_9ENTO     L7UV52     ? 5 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7X37 L 1 ? 107 ? 7X37       1   ? 107 ? 1 107 
2 2 7X37 H 1 ? 119 ? 7X37       1   ? 119 ? 1 119 
3 3 7X37 A 1 ? 278 ? W8GTF7     1   ? 278 ? 1 278 
4 4 7X37 B 1 ? 263 ? A0A2S0RQC2 70  ? 332 ? 1 263 
5 5 7X37 C 1 ? 238 ? L7UV52     333 ? 570 ? 1 238 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             7X37 
_struct_ref_seq_dif.mon_id                       LYS 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      84 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   W8GTF7 
_struct_ref_seq_dif.db_mon_id                    GLU 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          84 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            84 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7X37 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7X37 
_struct.title                        'Cryo-EM structure of Coxsackievirus B1 A particle in complex with nAb 2E6 (CVB1-A:2E6)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7X37 
_struct_keywords.text            'Coxsackievirus B1, Neutralizing antibody, Cryo-EM, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN B 86  ? THR B 90  ? GLN H 86  THR H 90  5 ? 5 
HELX_P HELX_P2  AA2 ASP B 99  ? TYR B 103 ? ASP H 99  TYR H 103 5 ? 5 
HELX_P HELX_P3  AA3 SER C 63  ? CYS C 69  ? SER A 63  CYS A 69  1 ? 7 
HELX_P HELX_P4  AA4 VAL C 97  ? GLU C 105 ? VAL A 97  GLU A 105 1 ? 9 
HELX_P HELX_P5  AA5 ASP C 156 ? THR C 161 ? ASP A 156 THR A 161 5 ? 6 
HELX_P HELX_P6  AA6 LEU D 82  ? LEU D 86  ? LEU B 82  LEU B 86  1 ? 5 
HELX_P HELX_P7  AA7 LEU D 91  ? HIS D 99  ? LEU B 91  HIS B 99  1 ? 9 
HELX_P HELX_P8  AA8 GLU D 142 ? SER D 147 ? GLU B 142 SER B 147 1 ? 6 
HELX_P HELX_P9  AA9 ALA D 171 ? ALA D 175 ? ALA B 171 ALA B 175 5 ? 5 
HELX_P HELX_P10 AB1 GLY D 180 ? LEU D 184 ? GLY B 180 LEU B 184 5 ? 5 
HELX_P HELX_P11 AB2 LEU E 43  ? GLU E 48  ? LEU C 43  GLU C 48  1 ? 6 
HELX_P HELX_P12 AB3 THR E 98  ? LEU E 104 ? THR C 98  LEU C 104 1 ? 7 
HELX_P HELX_P13 AB4 ASN E 144 ? LEU E 150 ? ASN C 144 LEU C 150 1 ? 7 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 23 SG ? ? ? 1_555 A CYS 88 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf2 disulf ? ? B CYS 22 SG ? ? ? 1_555 B CYS 95 SG ? ? H CYS 22 H CYS 95 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7  A . ? SER 7  L PRO 8  A ? PRO 8  L 1 1.66 
2 PRO 94 A . ? PRO 94 L VAL 95 A ? VAL 95 L 1 7.44 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 4 ? 
AA4 ? 5 ? 
AA5 ? 5 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 9 ? 
AA9 ? 5 ? 
AB1 ? 5 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 5 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 2 4 ? anti-parallel 
AA5 2 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 6 ? parallel      
AA8 2 9 ? anti-parallel 
AA8 3 8 ? anti-parallel 
AA8 4 8 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 5 7 ? anti-parallel 
AA8 5 8 ? anti-parallel 
AA8 5 9 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 5 ? anti-parallel 
AB1 2 5 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 3 5 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 5   ? SER A 7   ? THR L 5   SER L 7   
AA1 2 VAL A 19  ? ARG A 24  ? VAL L 19  ARG L 24  
AA1 3 GLN A 70  ? ILE A 75  ? GLN L 70  ILE L 75  
AA1 4 PHE A 62  ? SER A 67  ? PHE L 62  SER L 67  
AA2 1 ASN A 53  ? LEU A 54  ? ASN L 53  LEU L 54  
AA2 2 GLN A 45  ? TYR A 49  ? GLN L 45  TYR L 49  
AA2 3 LEU A 33  ? GLN A 38  ? LEU L 33  GLN L 38  
AA2 4 SER A 85  ? HIS A 90  ? SER L 85  HIS L 90  
AA2 5 THR A 102 ? LYS A 103 ? THR L 102 LYS L 103 
AA3 1 LYS B 5   ? SER B 7   ? LYS H 5   SER H 7   
AA3 2 LEU B 18  ? THR B 23  ? LEU H 18  THR H 23  
AA3 3 GLN B 77  ? MET B 82  ? GLN H 77  MET H 82  
AA3 4 LEU B 67  ? ASP B 72  ? LEU H 67  ASP H 72  
AA4 1 THR B 57  ? TYR B 59  ? THR H 57  TYR H 59  
AA4 2 GLY B 44  ? ILE B 51  ? GLY H 44  ILE H 51  
AA4 3 VAL B 34  ? SER B 40  ? VAL H 34  SER H 40  
AA4 4 ILE B 92  ? LYS B 97  ? ILE H 92  LYS H 97  
AA4 5 THR B 113 ? SER B 114 ? THR H 113 SER H 114 
AA5 1 ALA C 72  ? THR C 80  ? ALA A 72  THR A 80  
AA5 2 TYR C 109 ? GLN C 124 ? TYR A 109 GLN A 124 
AA5 3 MET C 178 ? ILE C 180 ? MET A 178 ILE A 180 
AA5 4 TYR C 189 ? SER C 190 ? TYR A 189 SER A 190 
AA5 5 ILE C 229 ? TRP C 245 ? ILE A 229 TRP A 245 
AA6 1 TRP C 90  ? VAL C 91  ? TRP A 90  VAL A 91  
AA6 2 THR C 215 ? HIS C 220 ? THR A 215 HIS A 220 
AA6 3 THR C 138 ? VAL C 144 ? THR A 138 VAL A 144 
AA6 4 SER C 166 ? THR C 170 ? SER A 166 THR A 170 
AA7 1 ILE D 16  ? LEU D 18  ? ILE B 16  LEU B 18  
AA7 2 SER D 21  ? ILE D 23  ? SER B 21  ILE B 23  
AA8 1 VAL D 32  ? VAL D 33  ? VAL B 32  VAL B 33  
AA8 2 PRO D 53  ? THR D 54  ? PRO B 53  THR B 54  
AA8 3 TYR D 64  ? THR D 65  ? TYR B 64  THR B 65  
AA8 4 VAL D 69  ? TRP D 71  ? VAL B 69  TRP B 71  
AA8 5 LEU D 101 ? CYS D 112 ? LEU B 101 CYS B 112 
AA8 6 SER D 199 ? MET D 204 ? SER B 199 MET B 204 
AA8 7 ASP D 213 ? ASN D 214 ? ASP B 213 ASN B 214 
AA8 8 VAL D 241 ? ILE D 247 ? VAL B 241 ILE B 247 
AA8 9 MET D 250 ? ASN D 255 ? MET B 250 ASN B 255 
AA9 1 ARG D 153 ? MET D 154 ? ARG B 153 MET B 154 
AA9 2 TRP D 78  ? LYS D 81  ? TRP B 78  LYS B 81  
AA9 3 LEU D 221 ? ASN D 232 ? LEU B 221 ASN B 232 
AA9 4 GLN D 119 ? PRO D 128 ? GLN B 119 PRO B 128 
AA9 5 HIS D 189 ? ASN D 193 ? HIS B 189 ASN B 193 
AB1 1 SER E 51  ? VAL E 52  ? SER C 51  VAL C 52  
AB1 2 ILE E 70  ? VAL E 72  ? ILE C 70  VAL C 72  
AB1 3 SER E 111 ? CYS E 121 ? SER C 111 CYS C 121 
AB1 4 VAL E 165 ? ILE E 171 ? VAL C 165 ILE C 171 
AB1 5 CYS E 208 ? VAL E 214 ? CYS C 208 VAL C 214 
AB2 1 GLN E 81  ? PHE E 83  ? GLN C 81  PHE C 83  
AB2 2 CYS E 192 ? TYR E 194 ? CYS C 192 TYR C 194 
AB2 3 LYS E 129 ? LEU E 132 ? LYS C 129 LEU C 132 
AB2 4 ILE E 155 ? ASP E 157 ? ILE C 155 ASP C 157 
AB3 1 TYR E 107 ? HIS E 109 ? TYR C 107 HIS C 109 
AB3 2 ARG E 223 ? LEU E 225 ? ARG C 223 LEU C 225 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER L 7   O THR A 22  ? O THR L 22  
AA1 2 3 N ILE A 21  ? N ILE L 21  O LEU A 73  ? O LEU L 73  
AA1 3 4 O LYS A 74  ? O LYS L 74  N SER A 63  ? N SER L 63  
AA2 1 2 O ASN A 53  ? O ASN L 53  N TYR A 49  ? N TYR L 49  
AA2 2 3 O VAL A 48  ? O VAL L 48  N TRP A 35  ? N TRP L 35  
AA2 3 4 N GLN A 38  ? N GLN L 38  O SER A 85  ? O SER L 85  
AA2 4 5 N TYR A 86  ? N TYR L 86  O THR A 102 ? O THR L 102 
AA3 1 2 N LYS B 5   ? N LYS H 5   O THR B 23  ? O THR H 23  
AA3 2 3 N LEU B 18  ? N LEU H 18  O MET B 82  ? O MET H 82  
AA3 3 4 O PHE B 79  ? O PHE H 79  N THR B 70  ? N THR H 70  
AA4 1 2 O ASP B 58  ? O ASP H 58  N VAL B 50  ? N VAL H 50  
AA4 2 3 O LEU B 48  ? O LEU H 48  N TRP B 36  ? N TRP H 36  
AA4 3 4 N HIS B 35  ? N HIS H 35  O ALA B 96  ? O ALA H 96  
AA4 4 5 N TYR B 93  ? N TYR H 93  O THR B 113 ? O THR H 113 
AA5 1 5 N TYR C 79  ? N TYR A 79  O SER C 231 ? O SER A 231 
AA5 2 3 N LEU C 114 ? N LEU A 114 O ILE C 180 ? O ILE A 180 
AA5 2 4 N LEU C 110 ? N LEU A 110 O TYR C 189 ? O TYR A 189 
AA5 2 5 N ASP C 113 ? N ASP A 113 O LYS C 240 ? O LYS A 240 
AA6 1 2 N TRP C 90  ? N TRP A 90  O LEU C 216 ? O LEU A 216 
AA6 2 3 O THR C 215 ? O THR A 215 N VAL C 144 ? N VAL A 144 
AA6 3 4 N HIS C 139 ? N HIS A 139 O TRP C 169 ? O TRP A 169 
AA7 1 2 N LEU D 18  ? N LEU B 18  O SER D 21  ? O SER B 21  
AA8 1 6 N VAL D 32  ? N VAL B 32  O THR D 201 ? O THR B 201 
AA8 2 9 N THR D 54  ? N THR B 54  O TYR D 254 ? O TYR B 254 
AA8 3 8 N TYR D 64  ? N TYR B 64  O ILE D 247 ? O ILE B 247 
AA8 4 8 N VAL D 69  ? N VAL B 69  O ILE D 243 ? O ILE B 243 
AA8 5 6 N VAL D 110 ? N VAL B 110 O ALA D 200 ? O ALA B 200 
AA8 5 7 N GLY D 102 ? N GLY B 102 O ASP D 213 ? O ASP B 213 
AA8 5 8 N HIS D 109 ? N HIS B 109 O THR D 246 ? O THR B 246 
AA8 5 9 N ARG D 103 ? N ARG B 103 O GLU D 253 ? O GLU B 253 
AA9 1 2 O ARG D 153 ? O ARG B 153 N TRP D 79  ? N TRP B 79  
AA9 2 3 N TRP D 80  ? N TRP B 80  O LEU D 223 ? O LEU B 223 
AA9 3 4 O THR D 222 ? O THR B 222 N VAL D 127 ? N VAL B 127 
AA9 4 5 N LEU D 122 ? N LEU B 122 O ILE D 192 ? O ILE B 192 
AB1 1 5 N SER E 51  ? N SER C 51  O VAL E 214 ? O VAL C 214 
AB1 2 5 N VAL E 72  ? N VAL C 72  O CYS E 208 ? O CYS C 208 
AB1 3 4 N GLY E 112 ? N GLY C 112 O TRP E 170 ? O TRP C 170 
AB1 3 5 N THR E 117 ? N THR C 117 O PHE E 213 ? O PHE C 213 
AB2 1 2 N VAL E 82  ? N VAL C 82  O CYS E 192 ? O CYS C 192 
AB2 2 3 O TRP E 193 ? O TRP C 193 N LEU E 131 ? N LEU C 131 
AB2 3 4 N PHE E 130 ? N PHE C 130 O TRP E 156 ? O TRP C 156 
AB3 1 2 N THR E 108 ? N THR C 108 O MET E 224 ? O MET C 224 
# 
_atom_sites.entry_id                    7X37 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ASP A 1 1   ? 348.810 340.871 484.702 1.00 155.32 ? 1   ASP L N   1 
ATOM 2    C CA  . ASP A 1 1   ? 347.841 341.413 483.758 1.00 155.32 ? 1   ASP L CA  1 
ATOM 3    C C   . ASP A 1 1   ? 347.956 342.931 483.649 1.00 155.32 ? 1   ASP L C   1 
ATOM 4    O O   . ASP A 1 1   ? 349.045 343.487 483.781 1.00 155.32 ? 1   ASP L O   1 
ATOM 5    C CB  . ASP A 1 1   ? 346.424 340.995 484.158 1.00 155.32 ? 1   ASP L CB  1 
ATOM 6    C CG  . ASP A 1 1   ? 346.066 341.407 485.571 1.00 155.32 ? 1   ASP L CG  1 
ATOM 7    O OD1 . ASP A 1 1   ? 345.720 342.588 485.779 1.00 155.32 ? 1   ASP L OD1 1 
ATOM 8    O OD2 . ASP A 1 1   ? 346.119 340.546 486.472 1.00 155.32 ? 1   ASP L OD2 1 
ATOM 9    N N   . ILE A 1 2   ? 346.832 343.600 483.413 1.00 148.38 ? 2   ILE L N   1 
ATOM 10   C CA  . ILE A 1 2   ? 346.831 345.028 483.116 1.00 148.38 ? 2   ILE L CA  1 
ATOM 11   C C   . ILE A 1 2   ? 345.723 345.700 483.915 1.00 148.38 ? 2   ILE L C   1 
ATOM 12   O O   . ILE A 1 2   ? 344.582 345.231 483.932 1.00 148.38 ? 2   ILE L O   1 
ATOM 13   C CB  . ILE A 1 2   ? 346.686 345.266 481.598 1.00 148.38 ? 2   ILE L CB  1 
ATOM 14   C CG1 . ILE A 1 2   ? 346.357 346.722 481.289 1.00 148.38 ? 2   ILE L CG1 1 
ATOM 15   C CG2 . ILE A 1 2   ? 345.682 344.307 480.984 1.00 148.38 ? 2   ILE L CG2 1 
ATOM 16   C CD1 . ILE A 1 2   ? 346.675 347.107 479.884 1.00 148.38 ? 2   ILE L CD1 1 
ATOM 17   N N   . GLN A 1 3   ? 346.067 346.795 484.592 1.00 150.03 ? 3   GLN L N   1 
ATOM 18   C CA  . GLN A 1 3   ? 345.153 347.503 485.474 1.00 150.03 ? 3   GLN L CA  1 
ATOM 19   C C   . GLN A 1 3   ? 344.702 348.805 484.831 1.00 150.03 ? 3   GLN L C   1 
ATOM 20   O O   . GLN A 1 3   ? 345.486 349.483 484.161 1.00 150.03 ? 3   GLN L O   1 
ATOM 21   C CB  . GLN A 1 3   ? 345.809 347.798 486.822 1.00 150.03 ? 3   GLN L CB  1 
ATOM 22   C CG  . GLN A 1 3   ? 346.589 346.635 487.402 1.00 150.03 ? 3   GLN L CG  1 
ATOM 23   C CD  . GLN A 1 3   ? 345.717 345.431 487.690 1.00 150.03 ? 3   GLN L CD  1 
ATOM 24   O OE1 . GLN A 1 3   ? 344.580 345.566 488.143 1.00 150.03 ? 3   GLN L OE1 1 
ATOM 25   N NE2 . GLN A 1 3   ? 346.249 344.243 487.436 1.00 150.03 ? 3   GLN L NE2 1 
ATOM 26   N N   . MET A 1 4   ? 343.435 349.147 485.043 1.00 145.99 ? 4   MET L N   1 
ATOM 27   C CA  . MET A 1 4   ? 342.846 350.373 484.524 1.00 145.99 ? 4   MET L CA  1 
ATOM 28   C C   . MET A 1 4   ? 342.644 351.354 485.672 1.00 145.99 ? 4   MET L C   1 
ATOM 29   O O   . MET A 1 4   ? 341.808 351.120 486.550 1.00 145.99 ? 4   MET L O   1 
ATOM 30   C CB  . MET A 1 4   ? 341.516 350.085 483.834 1.00 145.99 ? 4   MET L CB  1 
ATOM 31   C CG  . MET A 1 4   ? 341.491 348.795 483.047 1.00 145.99 ? 4   MET L CG  1 
ATOM 32   S SD  . MET A 1 4   ? 342.341 348.955 481.474 1.00 145.99 ? 4   MET L SD  1 
ATOM 33   C CE  . MET A 1 4   ? 341.600 350.463 480.866 1.00 145.99 ? 4   MET L CE  1 
ATOM 34   N N   . THR A 1 5   ? 343.402 352.445 485.663 1.00 149.42 ? 5   THR L N   1 
ATOM 35   C CA  . THR A 1 5   ? 343.293 353.481 486.682 1.00 149.42 ? 5   THR L CA  1 
ATOM 36   C C   . THR A 1 5   ? 342.408 354.601 486.155 1.00 149.42 ? 5   THR L C   1 
ATOM 37   O O   . THR A 1 5   ? 342.808 355.339 485.251 1.00 149.42 ? 5   THR L O   1 
ATOM 38   C CB  . THR A 1 5   ? 344.668 354.025 487.059 1.00 149.42 ? 5   THR L CB  1 
ATOM 39   O OG1 . THR A 1 5   ? 345.262 354.646 485.914 1.00 149.42 ? 5   THR L OG1 1 
ATOM 40   C CG2 . THR A 1 5   ? 345.564 352.898 487.531 1.00 149.42 ? 5   THR L CG2 1 
ATOM 41   N N   . GLN A 1 6   ? 341.218 354.733 486.728 1.00 149.60 ? 6   GLN L N   1 
ATOM 42   C CA  . GLN A 1 6   ? 340.224 355.696 486.281 1.00 149.60 ? 6   GLN L CA  1 
ATOM 43   C C   . GLN A 1 6   ? 340.223 356.899 487.209 1.00 149.60 ? 6   GLN L C   1 
ATOM 44   O O   . GLN A 1 6   ? 340.219 356.742 488.434 1.00 149.60 ? 6   GLN L O   1 
ATOM 45   C CB  . GLN A 1 6   ? 338.839 355.053 486.243 1.00 149.60 ? 6   GLN L CB  1 
ATOM 46   C CG  . GLN A 1 6   ? 337.738 355.965 485.777 1.00 149.60 ? 6   GLN L CG  1 
ATOM 47   C CD  . GLN A 1 6   ? 336.452 355.217 485.549 1.00 149.60 ? 6   GLN L CD  1 
ATOM 48   O OE1 . GLN A 1 6   ? 336.401 353.997 485.691 1.00 149.60 ? 6   GLN L OE1 1 
ATOM 49   N NE2 . GLN A 1 6   ? 335.398 355.941 485.201 1.00 149.60 ? 6   GLN L NE2 1 
ATOM 50   N N   . SER A 1 7   ? 340.225 358.097 486.626 1.00 152.40 ? 7   SER L N   1 
ATOM 51   C CA  . SER A 1 7   ? 340.245 359.343 487.373 1.00 152.40 ? 7   SER L CA  1 
ATOM 52   C C   . SER A 1 7   ? 339.299 360.334 486.709 1.00 152.40 ? 7   SER L C   1 
ATOM 53   O O   . SER A 1 7   ? 339.238 360.392 485.473 1.00 152.40 ? 7   SER L O   1 
ATOM 54   C CB  . SER A 1 7   ? 341.659 359.935 487.430 1.00 152.40 ? 7   SER L CB  1 
ATOM 55   O OG  . SER A 1 7   ? 341.903 360.755 486.303 1.00 152.40 ? 7   SER L OG  1 
ATOM 56   N N   . PRO A 1 8   ? 338.556 361.136 487.490 1.00 154.77 ? 8   PRO L N   1 
ATOM 57   C CA  . PRO A 1 8   ? 338.540 361.228 488.952 1.00 154.77 ? 8   PRO L CA  1 
ATOM 58   C C   . PRO A 1 8   ? 337.601 360.225 489.603 1.00 154.77 ? 8   PRO L C   1 
ATOM 59   O O   . PRO A 1 8   ? 336.852 359.545 488.908 1.00 154.77 ? 8   PRO L O   1 
ATOM 60   C CB  . PRO A 1 8   ? 338.052 362.650 489.192 1.00 154.77 ? 8   PRO L CB  1 
ATOM 61   C CG  . PRO A 1 8   ? 337.112 362.886 488.070 1.00 154.77 ? 8   PRO L CG  1 
ATOM 62   C CD  . PRO A 1 8   ? 337.652 362.127 486.882 1.00 154.77 ? 8   PRO L CD  1 
ATOM 63   N N   . ALA A 1 9   ? 337.643 360.145 490.932 1.00 157.59 ? 9   ALA L N   1 
ATOM 64   C CA  . ALA A 1 9   ? 336.829 359.168 491.642 1.00 157.59 ? 9   ALA L CA  1 
ATOM 65   C C   . ALA A 1 9   ? 335.369 359.598 491.720 1.00 157.59 ? 9   ALA L C   1 
ATOM 66   O O   . ALA A 1 9   ? 334.477 358.747 491.803 1.00 157.59 ? 9   ALA L O   1 
ATOM 67   C CB  . ALA A 1 9   ? 337.390 358.938 493.044 1.00 157.59 ? 9   ALA L CB  1 
ATOM 68   N N   . SER A 1 10  ? 335.107 360.903 491.700 1.00 160.42 ? 10  SER L N   1 
ATOM 69   C CA  . SER A 1 10  ? 333.745 361.410 491.769 1.00 160.42 ? 10  SER L CA  1 
ATOM 70   C C   . SER A 1 10  ? 333.693 362.801 491.160 1.00 160.42 ? 10  SER L C   1 
ATOM 71   O O   . SER A 1 10  ? 334.716 363.471 491.002 1.00 160.42 ? 10  SER L O   1 
ATOM 72   C CB  . SER A 1 10  ? 333.226 361.450 493.209 1.00 160.42 ? 10  SER L CB  1 
ATOM 73   O OG  . SER A 1 10  ? 331.919 361.992 493.253 1.00 160.42 ? 10  SER L OG  1 
ATOM 74   N N   . LEU A 1 11  ? 332.481 363.229 490.820 1.00 163.11 ? 11  LEU L N   1 
ATOM 75   C CA  . LEU A 1 11  ? 332.260 364.553 490.262 1.00 163.11 ? 11  LEU L CA  1 
ATOM 76   C C   . LEU A 1 11  ? 330.911 365.077 490.727 1.00 163.11 ? 11  LEU L C   1 
ATOM 77   O O   . LEU A 1 11  ? 330.010 364.312 491.079 1.00 163.11 ? 11  LEU L O   1 
ATOM 78   C CB  . LEU A 1 11  ? 332.325 364.542 488.731 1.00 163.11 ? 11  LEU L CB  1 
ATOM 79   C CG  . LEU A 1 11  ? 333.684 364.840 488.096 1.00 163.11 ? 11  LEU L CG  1 
ATOM 80   C CD1 . LEU A 1 11  ? 333.532 365.075 486.604 1.00 163.11 ? 11  LEU L CD1 1 
ATOM 81   C CD2 . LEU A 1 11  ? 334.346 366.035 488.760 1.00 163.11 ? 11  LEU L CD2 1 
ATOM 82   N N   . SER A 1 12  ? 330.783 366.401 490.725 1.00 169.26 ? 12  SER L N   1 
ATOM 83   C CA  . SER A 1 12  ? 329.561 367.081 491.138 1.00 169.26 ? 12  SER L CA  1 
ATOM 84   C C   . SER A 1 12  ? 329.338 368.261 490.204 1.00 169.26 ? 12  SER L C   1 
ATOM 85   O O   . SER A 1 12  ? 330.028 369.279 490.309 1.00 169.26 ? 12  SER L O   1 
ATOM 86   C CB  . SER A 1 12  ? 329.652 367.543 492.591 1.00 169.26 ? 12  SER L CB  1 
ATOM 87   O OG  . SER A 1 12  ? 330.819 368.317 492.799 1.00 169.26 ? 12  SER L OG  1 
ATOM 88   N N   . VAL A 1 13  ? 328.380 368.123 489.293 1.00 169.43 ? 13  VAL L N   1 
ATOM 89   C CA  . VAL A 1 13  ? 328.084 369.122 488.281 1.00 169.43 ? 13  VAL L CA  1 
ATOM 90   C C   . VAL A 1 13  ? 326.599 369.459 488.348 1.00 169.43 ? 13  VAL L C   1 
ATOM 91   O O   . VAL A 1 13  ? 325.887 369.036 489.255 1.00 169.43 ? 13  VAL L O   1 
ATOM 92   C CB  . VAL A 1 13  ? 328.478 368.658 486.863 1.00 169.43 ? 13  VAL L CB  1 
ATOM 93   C CG1 . VAL A 1 13  ? 329.972 368.395 486.772 1.00 169.43 ? 13  VAL L CG1 1 
ATOM 94   C CG2 . VAL A 1 13  ? 327.707 367.404 486.488 1.00 169.43 ? 13  VAL L CG2 1 
ATOM 95   N N   . SER A 1 14  ? 326.150 370.264 487.391 1.00 170.56 ? 14  SER L N   1 
ATOM 96   C CA  . SER A 1 14  ? 324.739 370.550 487.201 1.00 170.56 ? 14  SER L CA  1 
ATOM 97   C C   . SER A 1 14  ? 324.318 370.013 485.842 1.00 170.56 ? 14  SER L C   1 
ATOM 98   O O   . SER A 1 14  ? 325.004 369.188 485.236 1.00 170.56 ? 14  SER L O   1 
ATOM 99   C CB  . SER A 1 14  ? 324.444 372.050 487.293 1.00 170.56 ? 14  SER L CB  1 
ATOM 100  O OG  . SER A 1 14  ? 324.575 372.664 486.024 1.00 170.56 ? 14  SER L OG  1 
ATOM 101  N N   . VAL A 1 15  ? 323.166 370.472 485.371 1.00 167.15 ? 15  VAL L N   1 
ATOM 102  C CA  . VAL A 1 15  ? 322.699 370.121 484.036 1.00 167.15 ? 15  VAL L CA  1 
ATOM 103  C C   . VAL A 1 15  ? 323.285 371.105 483.031 1.00 167.15 ? 15  VAL L C   1 
ATOM 104  O O   . VAL A 1 15  ? 323.127 372.321 483.176 1.00 167.15 ? 15  VAL L O   1 
ATOM 105  C CB  . VAL A 1 15  ? 321.167 370.116 483.975 1.00 167.15 ? 15  VAL L CB  1 
ATOM 106  C CG1 . VAL A 1 15  ? 320.693 369.817 482.567 1.00 167.15 ? 15  VAL L CG1 1 
ATOM 107  C CG2 . VAL A 1 15  ? 320.609 369.105 484.958 1.00 167.15 ? 15  VAL L CG2 1 
ATOM 108  N N   . GLY A 1 16  ? 323.970 370.584 482.012 1.00 168.96 ? 16  GLY L N   1 
ATOM 109  C CA  . GLY A 1 16  ? 324.363 371.386 480.871 1.00 168.96 ? 16  GLY L CA  1 
ATOM 110  C C   . GLY A 1 16  ? 325.840 371.691 480.725 1.00 168.96 ? 16  GLY L C   1 
ATOM 111  O O   . GLY A 1 16  ? 326.187 372.580 479.939 1.00 168.96 ? 16  GLY L O   1 
ATOM 112  N N   . GLU A 1 17  ? 326.717 370.998 481.442 1.00 169.46 ? 17  GLU L N   1 
ATOM 113  C CA  . GLU A 1 17  ? 328.149 371.242 481.349 1.00 169.46 ? 17  GLU L CA  1 
ATOM 114  C C   . GLU A 1 17  ? 328.844 370.177 480.512 1.00 169.46 ? 17  GLU L C   1 
ATOM 115  O O   . GLU A 1 17  ? 328.262 369.148 480.162 1.00 169.46 ? 17  GLU L O   1 
ATOM 116  C CB  . GLU A 1 17  ? 328.796 371.296 482.735 1.00 169.46 ? 17  GLU L CB  1 
ATOM 117  C CG  . GLU A 1 17  ? 328.493 372.553 483.528 1.00 169.46 ? 17  GLU L CG  1 
ATOM 118  C CD  . GLU A 1 17  ? 327.186 372.471 484.281 1.00 169.46 ? 17  GLU L CD  1 
ATOM 119  O OE1 . GLU A 1 17  ? 326.537 371.409 484.225 1.00 169.46 ? 17  GLU L OE1 1 
ATOM 120  O OE2 . GLU A 1 17  ? 326.803 373.466 484.933 1.00 169.46 ? 17  GLU L OE2 1 
ATOM 121  N N   . THR A 1 18  ? 330.105 370.447 480.191 1.00 164.75 ? 18  THR L N   1 
ATOM 122  C CA  . THR A 1 18  ? 330.967 369.487 479.520 1.00 164.75 ? 18  THR L CA  1 
ATOM 123  C C   . THR A 1 18  ? 331.857 368.810 480.552 1.00 164.75 ? 18  THR L C   1 
ATOM 124  O O   . THR A 1 18  ? 332.593 369.482 481.281 1.00 164.75 ? 18  THR L O   1 
ATOM 125  C CB  . THR A 1 18  ? 331.830 370.179 478.465 1.00 164.75 ? 18  THR L CB  1 
ATOM 126  O OG1 . THR A 1 18  ? 332.584 371.230 479.081 1.00 164.75 ? 18  THR L OG1 1 
ATOM 127  C CG2 . THR A 1 18  ? 330.965 370.771 477.367 1.00 164.75 ? 18  THR L CG2 1 
ATOM 128  N N   . VAL A 1 19  ? 331.790 367.484 480.616 1.00 156.76 ? 19  VAL L N   1 
ATOM 129  C CA  . VAL A 1 19  ? 332.581 366.700 481.556 1.00 156.76 ? 19  VAL L CA  1 
ATOM 130  C C   . VAL A 1 19  ? 333.488 365.767 480.768 1.00 156.76 ? 19  VAL L C   1 
ATOM 131  O O   . VAL A 1 19  ? 333.247 365.511 479.582 1.00 156.76 ? 19  VAL L O   1 
ATOM 132  C CB  . VAL A 1 19  ? 331.691 365.912 482.535 1.00 156.76 ? 19  VAL L CB  1 
ATOM 133  C CG1 . VAL A 1 19  ? 330.776 366.854 483.292 1.00 156.76 ? 19  VAL L CG1 1 
ATOM 134  C CG2 . VAL A 1 19  ? 330.880 364.878 481.795 1.00 156.76 ? 19  VAL L CG2 1 
ATOM 135  N N   . THR A 1 20  ? 334.545 365.286 481.416 1.00 148.09 ? 20  THR L N   1 
ATOM 136  C CA  . THR A 1 20  ? 335.514 364.396 480.793 1.00 148.09 ? 20  THR L CA  1 
ATOM 137  C C   . THR A 1 20  ? 335.998 363.390 481.826 1.00 148.09 ? 20  THR L C   1 
ATOM 138  O O   . THR A 1 20  ? 336.511 363.778 482.879 1.00 148.09 ? 20  THR L O   1 
ATOM 139  C CB  . THR A 1 20  ? 336.687 365.187 480.216 1.00 148.09 ? 20  THR L CB  1 
ATOM 140  O OG1 . THR A 1 20  ? 336.239 365.939 479.083 1.00 148.09 ? 20  THR L OG1 1 
ATOM 141  C CG2 . THR A 1 20  ? 337.806 364.253 479.788 1.00 148.09 ? 20  THR L CG2 1 
ATOM 142  N N   . ILE A 1 21  ? 335.830 362.106 481.525 1.00 142.25 ? 21  ILE L N   1 
ATOM 143  C CA  . ILE A 1 21  ? 336.256 361.017 482.394 1.00 142.25 ? 21  ILE L CA  1 
ATOM 144  C C   . ILE A 1 21  ? 337.319 360.213 481.665 1.00 142.25 ? 21  ILE L C   1 
ATOM 145  O O   . ILE A 1 21  ? 337.071 359.711 480.564 1.00 142.25 ? 21  ILE L O   1 
ATOM 146  C CB  . ILE A 1 21  ? 335.078 360.111 482.784 1.00 142.25 ? 21  ILE L CB  1 
ATOM 147  C CG1 . ILE A 1 21  ? 333.905 360.948 483.281 1.00 142.25 ? 21  ILE L CG1 1 
ATOM 148  C CG2 . ILE A 1 21  ? 335.512 359.121 483.838 1.00 142.25 ? 21  ILE L CG2 1 
ATOM 149  C CD1 . ILE A 1 21  ? 332.631 360.165 483.430 1.00 142.25 ? 21  ILE L CD1 1 
ATOM 150  N N   . THR A 1 22  ? 338.491 360.083 482.275 1.00 144.52 ? 22  THR L N   1 
ATOM 151  C CA  . THR A 1 22  ? 339.609 359.382 481.666 1.00 144.52 ? 22  THR L CA  1 
ATOM 152  C C   . THR A 1 22  ? 339.982 358.152 482.480 1.00 144.52 ? 22  THR L C   1 
ATOM 153  O O   . THR A 1 22  ? 339.853 358.129 483.706 1.00 144.52 ? 22  THR L O   1 
ATOM 154  C CB  . THR A 1 22  ? 340.833 360.293 481.551 1.00 144.52 ? 22  THR L CB  1 
ATOM 155  O OG1 . THR A 1 22  ? 341.275 360.655 482.864 1.00 144.52 ? 22  THR L OG1 1 
ATOM 156  C CG2 . THR A 1 22  ? 340.492 361.553 480.778 1.00 144.52 ? 22  THR L CG2 1 
ATOM 157  N N   . CYS A 1 23  ? 340.455 357.122 481.782 1.00 144.86 ? 23  CYS L N   1 
ATOM 158  C CA  . CYS A 1 23  ? 341.074 355.981 482.438 1.00 144.86 ? 23  CYS L CA  1 
ATOM 159  C C   . CYS A 1 23  ? 342.280 355.546 481.625 1.00 144.86 ? 23  CYS L C   1 
ATOM 160  O O   . CYS A 1 23  ? 342.240 355.508 480.394 1.00 144.86 ? 23  CYS L O   1 
ATOM 161  C CB  . CYS A 1 23  ? 340.100 354.806 482.641 1.00 144.86 ? 23  CYS L CB  1 
ATOM 162  S SG  . CYS A 1 23  ? 339.491 353.927 481.185 1.00 144.86 ? 23  CYS L SG  1 
ATOM 163  N N   . ARG A 1 24  ? 343.358 355.226 482.330 1.00 145.72 ? 24  ARG L N   1 
ATOM 164  C CA  . ARG A 1 24  ? 344.643 354.930 481.722 1.00 145.72 ? 24  ARG L CA  1 
ATOM 165  C C   . ARG A 1 24  ? 345.010 353.481 481.989 1.00 145.72 ? 24  ARG L C   1 
ATOM 166  O O   . ARG A 1 24  ? 344.821 352.979 483.099 1.00 145.72 ? 24  ARG L O   1 
ATOM 167  C CB  . ARG A 1 24  ? 345.727 355.855 482.270 1.00 145.72 ? 24  ARG L CB  1 
ATOM 168  C CG  . ARG A 1 24  ? 346.989 355.899 481.441 1.00 145.72 ? 24  ARG L CG  1 
ATOM 169  C CD  . ARG A 1 24  ? 348.117 356.575 482.199 1.00 145.72 ? 24  ARG L CD  1 
ATOM 170  N NE  . ARG A 1 24  ? 348.672 355.705 483.232 1.00 145.72 ? 24  ARG L NE  1 
ATOM 171  C CZ  . ARG A 1 24  ? 348.472 355.872 484.535 1.00 145.72 ? 24  ARG L CZ  1 
ATOM 172  N NH1 . ARG A 1 24  ? 347.730 356.881 484.969 1.00 145.72 ? 24  ARG L NH1 1 
ATOM 173  N NH2 . ARG A 1 24  ? 349.014 355.031 485.405 1.00 145.72 ? 24  ARG L NH2 1 
ATOM 174  N N   . ALA A 1 25  ? 345.541 352.816 480.971 1.00 145.18 ? 25  ALA L N   1 
ATOM 175  C CA  . ALA A 1 25  ? 345.874 351.405 481.045 1.00 145.18 ? 25  ALA L CA  1 
ATOM 176  C C   . ALA A 1 25  ? 347.339 351.222 481.415 1.00 145.18 ? 25  ALA L C   1 
ATOM 177  O O   . ALA A 1 25  ? 348.138 352.160 481.364 1.00 145.18 ? 25  ALA L O   1 
ATOM 178  C CB  . ALA A 1 25  ? 345.575 350.706 479.717 1.00 145.18 ? 25  ALA L CB  1 
ATOM 179  N N   . SER A 1 26  ? 347.686 349.990 481.794 1.00 149.83 ? 26  SER L N   1 
ATOM 180  C CA  . SER A 1 26  ? 349.058 349.707 482.202 1.00 149.83 ? 26  SER L CA  1 
ATOM 181  C C   . SER A 1 26  ? 349.979 349.595 480.995 1.00 149.83 ? 26  SER L C   1 
ATOM 182  O O   . SER A 1 26  ? 351.132 350.035 481.046 1.00 149.83 ? 26  SER L O   1 
ATOM 183  C CB  . SER A 1 26  ? 349.104 348.428 483.033 1.00 149.83 ? 26  SER L CB  1 
ATOM 184  O OG  . SER A 1 26  ? 348.333 348.562 484.213 1.00 149.83 ? 26  SER L OG  1 
ATOM 185  N N   . GLU A 1 27  ? 349.494 349.003 479.908 1.00 149.14 ? 27  GLU L N   1 
ATOM 186  C CA  . GLU A 1 27  ? 350.212 348.970 478.644 1.00 149.14 ? 27  GLU L CA  1 
ATOM 187  C C   . GLU A 1 27  ? 349.209 349.196 477.521 1.00 149.14 ? 27  GLU L C   1 
ATOM 188  O O   . GLU A 1 27  ? 348.051 349.546 477.761 1.00 149.14 ? 27  GLU L O   1 
ATOM 189  C CB  . GLU A 1 27  ? 350.975 347.654 478.462 1.00 149.14 ? 27  GLU L CB  1 
ATOM 190  C CG  . GLU A 1 27  ? 350.098 346.422 478.403 1.00 149.14 ? 27  GLU L CG  1 
ATOM 191  C CD  . GLU A 1 27  ? 349.995 345.729 479.737 1.00 149.14 ? 27  GLU L CD  1 
ATOM 192  O OE1 . GLU A 1 27  ? 350.471 346.304 480.738 1.00 149.14 ? 27  GLU L OE1 1 
ATOM 193  O OE2 . GLU A 1 27  ? 349.443 344.610 479.786 1.00 149.14 ? 27  GLU L OE2 1 
ATOM 194  N N   . ASN A 1 28  ? 349.661 349.001 476.287 1.00 138.46 ? 28  ASN L N   1 
ATOM 195  C CA  . ASN A 1 28  ? 348.816 349.256 475.130 1.00 138.46 ? 28  ASN L CA  1 
ATOM 196  C C   . ASN A 1 28  ? 347.753 348.175 474.994 1.00 138.46 ? 28  ASN L C   1 
ATOM 197  O O   . ASN A 1 28  ? 348.021 346.993 475.224 1.00 138.46 ? 28  ASN L O   1 
ATOM 198  C CB  . ASN A 1 28  ? 349.669 349.327 473.868 1.00 138.46 ? 28  ASN L CB  1 
ATOM 199  C CG  . ASN A 1 28  ? 348.950 349.987 472.716 1.00 138.46 ? 28  ASN L CG  1 
ATOM 200  O OD1 . ASN A 1 28  ? 347.798 350.393 472.838 1.00 138.46 ? 28  ASN L OD1 1 
ATOM 201  N ND2 . ASN A 1 28  ? 349.634 350.109 471.588 1.00 138.46 ? 28  ASN L ND2 1 
ATOM 202  N N   . VAL A 1 29  ? 346.539 348.585 474.626 1.00 130.83 ? 29  VAL L N   1 
ATOM 203  C CA  . VAL A 1 29  ? 345.425 347.668 474.422 1.00 130.83 ? 29  VAL L CA  1 
ATOM 204  C C   . VAL A 1 29  ? 344.859 347.740 473.018 1.00 130.83 ? 29  VAL L C   1 
ATOM 205  O O   . VAL A 1 29  ? 343.940 346.970 472.701 1.00 130.83 ? 29  VAL L O   1 
ATOM 206  C CB  . VAL A 1 29  ? 344.306 347.900 475.453 1.00 130.83 ? 29  VAL L CB  1 
ATOM 207  C CG1 . VAL A 1 29  ? 344.682 347.303 476.773 1.00 130.83 ? 29  VAL L CG1 1 
ATOM 208  C CG2 . VAL A 1 29  ? 344.048 349.373 475.616 1.00 130.83 ? 29  VAL L CG2 1 
ATOM 209  N N   . TYR A 1 30  ? 345.371 348.646 472.174 1.00 127.01 ? 30  TYR L N   1 
ATOM 210  C CA  . TYR A 1 30  ? 344.986 348.793 470.764 1.00 127.01 ? 30  TYR L CA  1 
ATOM 211  C C   . TYR A 1 30  ? 343.491 349.053 470.595 1.00 127.01 ? 30  TYR L C   1 
ATOM 212  O O   . TYR A 1 30  ? 342.810 348.350 469.846 1.00 127.01 ? 30  TYR L O   1 
ATOM 213  C CB  . TYR A 1 30  ? 345.419 347.586 469.933 1.00 127.01 ? 30  TYR L CB  1 
ATOM 214  C CG  . TYR A 1 30  ? 346.861 347.196 470.118 1.00 127.01 ? 30  TYR L CG  1 
ATOM 215  C CD1 . TYR A 1 30  ? 347.867 347.830 469.406 1.00 127.01 ? 30  TYR L CD1 1 
ATOM 216  C CD2 . TYR A 1 30  ? 347.216 346.185 470.995 1.00 127.01 ? 30  TYR L CD2 1 
ATOM 217  C CE1 . TYR A 1 30  ? 349.187 347.470 469.570 1.00 127.01 ? 30  TYR L CE1 1 
ATOM 218  C CE2 . TYR A 1 30  ? 348.530 345.817 471.165 1.00 127.01 ? 30  TYR L CE2 1 
ATOM 219  C CZ  . TYR A 1 30  ? 349.510 346.463 470.451 1.00 127.01 ? 30  TYR L CZ  1 
ATOM 220  O OH  . TYR A 1 30  ? 350.822 346.096 470.622 1.00 127.01 ? 30  TYR L OH  1 
ATOM 221  N N   . ARG A 1 31  ? 342.988 350.054 471.326 1.00 128.71 ? 31  ARG L N   1 
ATOM 222  C CA  . ARG A 1 31  ? 341.609 350.550 471.246 1.00 128.71 ? 31  ARG L CA  1 
ATOM 223  C C   . ARG A 1 31  ? 340.575 349.476 471.554 1.00 128.71 ? 31  ARG L C   1 
ATOM 224  O O   . ARG A 1 31  ? 339.463 349.510 471.028 1.00 128.71 ? 31  ARG L O   1 
ATOM 225  C CB  . ARG A 1 31  ? 341.313 351.187 469.887 1.00 128.71 ? 31  ARG L CB  1 
ATOM 226  C CG  . ARG A 1 31  ? 342.004 352.507 469.668 1.00 128.71 ? 31  ARG L CG  1 
ATOM 227  C CD  . ARG A 1 31  ? 341.200 353.388 468.738 1.00 128.71 ? 31  ARG L CD  1 
ATOM 228  N NE  . ARG A 1 31  ? 340.720 352.643 467.582 1.00 128.71 ? 31  ARG L NE  1 
ATOM 229  C CZ  . ARG A 1 31  ? 341.435 352.441 466.481 1.00 128.71 ? 31  ARG L CZ  1 
ATOM 230  N NH1 . ARG A 1 31  ? 342.662 352.931 466.387 1.00 128.71 ? 31  ARG L NH1 1 
ATOM 231  N NH2 . ARG A 1 31  ? 340.923 351.750 465.473 1.00 128.71 ? 31  ARG L NH2 1 
ATOM 232  N N   . ASN A 1 32  ? 340.921 348.515 472.405 1.00 125.12 ? 32  ASN L N   1 
ATOM 233  C CA  . ASN A 1 32  ? 339.980 347.481 472.824 1.00 125.12 ? 32  ASN L CA  1 
ATOM 234  C C   . ASN A 1 32  ? 339.393 347.902 474.166 1.00 125.12 ? 32  ASN L C   1 
ATOM 235  O O   . ASN A 1 32  ? 339.793 347.430 475.224 1.00 125.12 ? 32  ASN L O   1 
ATOM 236  C CB  . ASN A 1 32  ? 340.667 346.126 472.909 1.00 125.12 ? 32  ASN L CB  1 
ATOM 237  C CG  . ASN A 1 32  ? 341.016 345.570 471.554 1.00 125.12 ? 32  ASN L CG  1 
ATOM 238  O OD1 . ASN A 1 32  ? 340.302 344.730 471.012 1.00 125.12 ? 32  ASN L OD1 1 
ATOM 239  N ND2 . ASN A 1 32  ? 342.121 346.037 470.995 1.00 125.12 ? 32  ASN L ND2 1 
ATOM 240  N N   . LEU A 1 33  ? 338.421 348.807 474.111 1.00 126.03 ? 33  LEU L N   1 
ATOM 241  C CA  . LEU A 1 33  ? 337.886 349.413 475.318 1.00 126.03 ? 33  LEU L CA  1 
ATOM 242  C C   . LEU A 1 33  ? 336.374 349.529 475.220 1.00 126.03 ? 33  LEU L C   1 
ATOM 243  O O   . LEU A 1 33  ? 335.823 349.777 474.146 1.00 126.03 ? 33  LEU L O   1 
ATOM 244  C CB  . LEU A 1 33  ? 338.494 350.792 475.552 1.00 126.03 ? 33  LEU L CB  1 
ATOM 245  C CG  . LEU A 1 33  ? 338.382 351.302 476.979 1.00 126.03 ? 33  LEU L CG  1 
ATOM 246  C CD1 . LEU A 1 33  ? 339.423 350.627 477.828 1.00 126.03 ? 33  LEU L CD1 1 
ATOM 247  C CD2 . LEU A 1 33  ? 338.547 352.791 477.015 1.00 126.03 ? 33  LEU L CD2 1 
ATOM 248  N N   . ALA A 1 34  ? 335.706 349.348 476.356 1.00 130.79 ? 34  ALA L N   1 
ATOM 249  C CA  . ALA A 1 34  ? 334.265 349.502 476.448 1.00 130.79 ? 34  ALA L CA  1 
ATOM 250  C C   . ALA A 1 34  ? 333.921 350.345 477.666 1.00 130.79 ? 34  ALA L C   1 
ATOM 251  O O   . ALA A 1 34  ? 334.572 350.259 478.709 1.00 130.79 ? 34  ALA L O   1 
ATOM 252  C CB  . ALA A 1 34  ? 333.553 348.149 476.528 1.00 130.79 ? 34  ALA L CB  1 
ATOM 253  N N   . TRP A 1 35  ? 332.881 351.165 477.522 1.00 132.81 ? 35  TRP L N   1 
ATOM 254  C CA  . TRP A 1 35  ? 332.432 352.065 478.575 1.00 132.81 ? 35  TRP L CA  1 
ATOM 255  C C   . TRP A 1 35  ? 331.027 351.685 479.007 1.00 132.81 ? 35  TRP L C   1 
ATOM 256  O O   . TRP A 1 35  ? 330.176 351.379 478.169 1.00 132.81 ? 35  TRP L O   1 
ATOM 257  C CB  . TRP A 1 35  ? 332.442 353.514 478.109 1.00 132.81 ? 35  TRP L CB  1 
ATOM 258  C CG  . TRP A 1 35  ? 333.800 354.112 478.004 1.00 132.81 ? 35  TRP L CG  1 
ATOM 259  C CD1 . TRP A 1 35  ? 334.579 354.179 476.893 1.00 132.81 ? 35  TRP L CD1 1 
ATOM 260  C CD2 . TRP A 1 35  ? 334.533 354.758 479.046 1.00 132.81 ? 35  TRP L CD2 1 
ATOM 261  N NE1 . TRP A 1 35  ? 335.759 354.812 477.178 1.00 132.81 ? 35  TRP L NE1 1 
ATOM 262  C CE2 . TRP A 1 35  ? 335.754 355.180 478.496 1.00 132.81 ? 35  TRP L CE2 1 
ATOM 263  C CE3 . TRP A 1 35  ? 334.277 355.014 480.392 1.00 132.81 ? 35  TRP L CE3 1 
ATOM 264  C CZ2 . TRP A 1 35  ? 336.717 355.841 479.243 1.00 132.81 ? 35  TRP L CZ2 1 
ATOM 265  C CZ3 . TRP A 1 35  ? 335.232 355.671 481.130 1.00 132.81 ? 35  TRP L CZ3 1 
ATOM 266  C CH2 . TRP A 1 35  ? 336.438 356.076 480.557 1.00 132.81 ? 35  TRP L CH2 1 
ATOM 267  N N   . TYR A 1 36  ? 330.781 351.725 480.313 1.00 136.96 ? 36  TYR L N   1 
ATOM 268  C CA  . TYR A 1 36  ? 329.521 351.273 480.879 1.00 136.96 ? 36  TYR L CA  1 
ATOM 269  C C   . TYR A 1 36  ? 328.892 352.364 481.729 1.00 136.96 ? 36  TYR L C   1 
ATOM 270  O O   . TYR A 1 36  ? 329.576 353.265 482.219 1.00 136.96 ? 36  TYR L O   1 
ATOM 271  C CB  . TYR A 1 36  ? 329.713 350.023 481.728 1.00 136.96 ? 36  TYR L CB  1 
ATOM 272  C CG  . TYR A 1 36  ? 330.010 348.798 480.912 1.00 136.96 ? 36  TYR L CG  1 
ATOM 273  C CD1 . TYR A 1 36  ? 329.011 348.172 480.186 1.00 136.96 ? 36  TYR L CD1 1 
ATOM 274  C CD2 . TYR A 1 36  ? 331.288 348.270 480.861 1.00 136.96 ? 36  TYR L CD2 1 
ATOM 275  C CE1 . TYR A 1 36  ? 329.276 347.056 479.433 1.00 136.96 ? 36  TYR L CE1 1 
ATOM 276  C CE2 . TYR A 1 36  ? 331.560 347.155 480.113 1.00 136.96 ? 36  TYR L CE2 1 
ATOM 277  C CZ  . TYR A 1 36  ? 330.552 346.554 479.402 1.00 136.96 ? 36  TYR L CZ  1 
ATOM 278  O OH  . TYR A 1 36  ? 330.822 345.440 478.650 1.00 136.96 ? 36  TYR L OH  1 
ATOM 279  N N   . GLN A 1 37  ? 327.576 352.268 481.897 1.00 143.28 ? 37  GLN L N   1 
ATOM 280  C CA  . GLN A 1 37  ? 326.817 353.141 482.780 1.00 143.28 ? 37  GLN L CA  1 
ATOM 281  C C   . GLN A 1 37  ? 325.891 352.289 483.632 1.00 143.28 ? 37  GLN L C   1 
ATOM 282  O O   . GLN A 1 37  ? 325.110 351.495 483.098 1.00 143.28 ? 37  GLN L O   1 
ATOM 283  C CB  . GLN A 1 37  ? 326.003 354.172 481.994 1.00 143.28 ? 37  GLN L CB  1 
ATOM 284  C CG  . GLN A 1 37  ? 324.883 354.803 482.806 1.00 143.28 ? 37  GLN L CG  1 
ATOM 285  C CD  . GLN A 1 37  ? 324.078 355.811 482.024 1.00 143.28 ? 37  GLN L CD  1 
ATOM 286  O OE1 . GLN A 1 37  ? 322.950 355.539 481.616 1.00 143.28 ? 37  GLN L OE1 1 
ATOM 287  N NE2 . GLN A 1 37  ? 324.647 356.991 481.820 1.00 143.28 ? 37  GLN L NE2 1 
ATOM 288  N N   . GLN A 1 38  ? 325.979 352.450 484.948 1.00 148.04 ? 38  GLN L N   1 
ATOM 289  C CA  . GLN A 1 38  ? 325.137 351.717 485.880 1.00 148.04 ? 38  GLN L CA  1 
ATOM 290  C C   . GLN A 1 38  ? 324.366 352.701 486.741 1.00 148.04 ? 38  GLN L C   1 
ATOM 291  O O   . GLN A 1 38  ? 324.959 353.595 487.352 1.00 148.04 ? 38  GLN L O   1 
ATOM 292  C CB  . GLN A 1 38  ? 325.963 350.787 486.767 1.00 148.04 ? 38  GLN L CB  1 
ATOM 293  C CG  . GLN A 1 38  ? 325.119 349.918 487.679 1.00 148.04 ? 38  GLN L CG  1 
ATOM 294  C CD  . GLN A 1 38  ? 325.954 349.090 488.625 1.00 148.04 ? 38  GLN L CD  1 
ATOM 295  O OE1 . GLN A 1 38  ? 327.106 349.418 488.903 1.00 148.04 ? 38  GLN L OE1 1 
ATOM 296  N NE2 . GLN A 1 38  ? 325.378 348.006 489.129 1.00 148.04 ? 38  GLN L NE2 1 
ATOM 297  N N   . LYS A 1 39  ? 323.052 352.533 486.790 1.00 153.16 ? 39  LYS L N   1 
ATOM 298  C CA  . LYS A 1 39  ? 322.211 353.352 487.645 1.00 153.16 ? 39  LYS L CA  1 
ATOM 299  C C   . LYS A 1 39  ? 322.087 352.680 489.010 1.00 153.16 ? 39  LYS L C   1 
ATOM 300  O O   . LYS A 1 39  ? 322.822 351.744 489.336 1.00 153.16 ? 39  LYS L O   1 
ATOM 301  C CB  . LYS A 1 39  ? 320.859 353.596 486.984 1.00 153.16 ? 39  LYS L CB  1 
ATOM 302  C CG  . LYS A 1 39  ? 320.924 354.578 485.832 1.00 153.16 ? 39  LYS L CG  1 
ATOM 303  C CD  . LYS A 1 39  ? 319.555 354.838 485.237 1.00 153.16 ? 39  LYS L CD  1 
ATOM 304  C CE  . LYS A 1 39  ? 319.619 355.940 484.196 1.00 153.16 ? 39  LYS L CE  1 
ATOM 305  N NZ  . LYS A 1 39  ? 320.097 357.223 484.780 1.00 153.16 ? 39  LYS L NZ  1 
ATOM 306  N N   . GLN A 1 40  ? 321.157 353.157 489.828 1.00 158.10 ? 40  GLN L N   1 
ATOM 307  C CA  . GLN A 1 40  ? 321.070 352.743 491.226 1.00 158.10 ? 40  GLN L CA  1 
ATOM 308  C C   . GLN A 1 40  ? 320.438 351.360 491.314 1.00 158.10 ? 40  GLN L C   1 
ATOM 309  O O   . GLN A 1 40  ? 319.230 351.201 491.130 1.00 158.10 ? 40  GLN L O   1 
ATOM 310  C CB  . GLN A 1 40  ? 320.281 353.768 492.033 1.00 158.10 ? 40  GLN L CB  1 
ATOM 311  C CG  . GLN A 1 40  ? 321.031 355.075 492.344 1.00 158.10 ? 40  GLN L CG  1 
ATOM 312  C CD  . GLN A 1 40  ? 322.462 354.890 492.851 1.00 158.10 ? 40  GLN L CD  1 
ATOM 313  O OE1 . GLN A 1 40  ? 322.753 354.000 493.656 1.00 158.10 ? 40  GLN L OE1 1 
ATOM 314  N NE2 . GLN A 1 40  ? 323.364 355.738 492.370 1.00 158.10 ? 40  GLN L NE2 1 
ATOM 315  N N   . GLY A 1 41  ? 321.264 350.358 491.596 1.00 156.75 ? 41  GLY L N   1 
ATOM 316  C CA  . GLY A 1 41  ? 320.786 349.010 491.856 1.00 156.75 ? 41  GLY L CA  1 
ATOM 317  C C   . GLY A 1 41  ? 320.225 348.276 490.659 1.00 156.75 ? 41  GLY L C   1 
ATOM 318  O O   . GLY A 1 41  ? 319.251 347.526 490.799 1.00 156.75 ? 41  GLY L O   1 
ATOM 319  N N   . LYS A 1 42  ? 320.810 348.471 489.482 1.00 152.05 ? 42  LYS L N   1 
ATOM 320  C CA  . LYS A 1 42  ? 320.368 347.791 488.275 1.00 152.05 ? 42  LYS L CA  1 
ATOM 321  C C   . LYS A 1 42  ? 321.582 347.262 487.524 1.00 152.05 ? 42  LYS L C   1 
ATOM 322  O O   . LYS A 1 42  ? 322.731 347.539 487.877 1.00 152.05 ? 42  LYS L O   1 
ATOM 323  C CB  . LYS A 1 42  ? 319.536 348.722 487.387 1.00 152.05 ? 42  LYS L CB  1 
ATOM 324  C CG  . LYS A 1 42  ? 318.101 348.883 487.848 1.00 152.05 ? 42  LYS L CG  1 
ATOM 325  C CD  . LYS A 1 42  ? 317.337 349.838 486.953 1.00 152.05 ? 42  LYS L CD  1 
ATOM 326  C CE  . LYS A 1 42  ? 317.989 351.209 486.935 1.00 152.05 ? 42  LYS L CE  1 
ATOM 327  N NZ  . LYS A 1 42  ? 318.225 351.733 488.309 1.00 152.05 ? 42  LYS L NZ  1 
ATOM 328  N N   . SER A 1 43  ? 321.313 346.491 486.480 1.00 147.04 ? 43  SER L N   1 
ATOM 329  C CA  . SER A 1 43  ? 322.363 345.932 485.650 1.00 147.04 ? 43  SER L CA  1 
ATOM 330  C C   . SER A 1 43  ? 322.997 347.025 484.794 1.00 147.04 ? 43  SER L C   1 
ATOM 331  O O   . SER A 1 43  ? 322.293 347.884 484.257 1.00 147.04 ? 43  SER L O   1 
ATOM 332  C CB  . SER A 1 43  ? 321.800 344.840 484.754 1.00 147.04 ? 43  SER L CB  1 
ATOM 333  O OG  . SER A 1 43  ? 321.281 343.775 485.529 1.00 147.04 ? 43  SER L OG  1 
ATOM 334  N N   . PRO A 1 44  ? 324.322 347.027 484.672 1.00 142.12 ? 44  PRO L N   1 
ATOM 335  C CA  . PRO A 1 44  ? 324.986 348.050 483.863 1.00 142.12 ? 44  PRO L CA  1 
ATOM 336  C C   . PRO A 1 44  ? 324.716 347.845 482.383 1.00 142.12 ? 44  PRO L C   1 
ATOM 337  O O   . PRO A 1 44  ? 324.410 346.744 481.921 1.00 142.12 ? 44  PRO L O   1 
ATOM 338  C CB  . PRO A 1 44  ? 326.471 347.855 484.186 1.00 142.12 ? 44  PRO L CB  1 
ATOM 339  C CG  . PRO A 1 44  ? 326.496 347.039 485.430 1.00 142.12 ? 44  PRO L CG  1 
ATOM 340  C CD  . PRO A 1 44  ? 325.294 346.165 485.357 1.00 142.12 ? 44  PRO L CD  1 
ATOM 341  N N   . GLN A 1 45  ? 324.821 348.938 481.636 1.00 140.78 ? 45  GLN L N   1 
ATOM 342  C CA  . GLN A 1 45  ? 324.490 348.941 480.220 1.00 140.78 ? 45  GLN L CA  1 
ATOM 343  C C   . GLN A 1 45  ? 325.709 349.358 479.417 1.00 140.78 ? 45  GLN L C   1 
ATOM 344  O O   . GLN A 1 45  ? 326.505 350.182 479.875 1.00 140.78 ? 45  GLN L O   1 
ATOM 345  C CB  . GLN A 1 45  ? 323.319 349.883 479.932 1.00 140.78 ? 45  GLN L CB  1 
ATOM 346  C CG  . GLN A 1 45  ? 321.982 349.403 480.477 1.00 140.78 ? 45  GLN L CG  1 
ATOM 347  C CD  . GLN A 1 45  ? 321.797 347.900 480.356 1.00 140.78 ? 45  GLN L CD  1 
ATOM 348  O OE1 . GLN A 1 45  ? 321.732 347.356 479.253 1.00 140.78 ? 45  GLN L OE1 1 
ATOM 349  N NE2 . GLN A 1 45  ? 321.700 347.223 481.493 1.00 140.78 ? 45  GLN L NE2 1 
ATOM 350  N N   . LEU A 1 46  ? 325.853 348.783 478.229 1.00 134.56 ? 46  LEU L N   1 
ATOM 351  C CA  . LEU A 1 46  ? 326.945 349.153 477.343 1.00 134.56 ? 46  LEU L CA  1 
ATOM 352  C C   . LEU A 1 46  ? 326.693 350.533 476.760 1.00 134.56 ? 46  LEU L C   1 
ATOM 353  O O   . LEU A 1 46  ? 325.599 350.819 476.267 1.00 134.56 ? 46  LEU L O   1 
ATOM 354  C CB  . LEU A 1 46  ? 327.088 348.127 476.225 1.00 134.56 ? 46  LEU L CB  1 
ATOM 355  C CG  . LEU A 1 46  ? 328.212 348.392 475.231 1.00 134.56 ? 46  LEU L CG  1 
ATOM 356  C CD1 . LEU A 1 46  ? 329.501 347.763 475.715 1.00 134.56 ? 46  LEU L CD1 1 
ATOM 357  C CD2 . LEU A 1 46  ? 327.830 347.863 473.873 1.00 134.56 ? 46  LEU L CD2 1 
ATOM 358  N N   . LEU A 1 47  ? 327.705 351.392 476.815 1.00 133.05 ? 47  LEU L N   1 
ATOM 359  C CA  . LEU A 1 47  ? 327.561 352.768 476.364 1.00 133.05 ? 47  LEU L CA  1 
ATOM 360  C C   . LEU A 1 47  ? 328.391 353.066 475.127 1.00 133.05 ? 47  LEU L C   1 
ATOM 361  O O   . LEU A 1 47  ? 327.842 353.497 474.108 1.00 133.05 ? 47  LEU L O   1 
ATOM 362  C CB  . LEU A 1 47  ? 327.947 353.720 477.504 1.00 133.05 ? 47  LEU L CB  1 
ATOM 363  C CG  . LEU A 1 47  ? 327.244 355.069 477.557 1.00 133.05 ? 47  LEU L CG  1 
ATOM 364  C CD1 . LEU A 1 47  ? 325.798 354.869 477.940 1.00 133.05 ? 47  LEU L CD1 1 
ATOM 365  C CD2 . LEU A 1 47  ? 327.935 355.975 478.551 1.00 133.05 ? 47  LEU L CD2 1 
ATOM 366  N N   . VAL A 1 48  ? 329.701 352.843 475.185 1.00 129.62 ? 48  VAL L N   1 
ATOM 367  C CA  . VAL A 1 48  ? 330.609 353.090 474.070 1.00 129.62 ? 48  VAL L CA  1 
ATOM 368  C C   . VAL A 1 48  ? 331.560 351.908 473.984 1.00 129.62 ? 48  VAL L C   1 
ATOM 369  O O   . VAL A 1 48  ? 332.237 351.584 474.963 1.00 129.62 ? 48  VAL L O   1 
ATOM 370  C CB  . VAL A 1 48  ? 331.393 354.406 474.251 1.00 129.62 ? 48  VAL L CB  1 
ATOM 371  C CG1 . VAL A 1 48  ? 332.626 354.438 473.369 1.00 129.62 ? 48  VAL L CG1 1 
ATOM 372  C CG2 . VAL A 1 48  ? 330.516 355.595 473.946 1.00 129.62 ? 48  VAL L CG2 1 
ATOM 373  N N   . TYR A 1 49  ? 331.601 351.251 472.828 1.00 123.45 ? 49  TYR L N   1 
ATOM 374  C CA  . TYR A 1 49  ? 332.474 350.106 472.618 1.00 123.45 ? 49  TYR L CA  1 
ATOM 375  C C   . TYR A 1 49  ? 333.481 350.416 471.519 1.00 123.45 ? 49  TYR L C   1 
ATOM 376  O O   . TYR A 1 49  ? 333.216 351.215 470.618 1.00 123.45 ? 49  TYR L O   1 
ATOM 377  C CB  . TYR A 1 49  ? 331.674 348.841 472.277 1.00 123.45 ? 49  TYR L CB  1 
ATOM 378  C CG  . TYR A 1 49  ? 331.060 348.823 470.904 1.00 123.45 ? 49  TYR L CG  1 
ATOM 379  C CD1 . TYR A 1 49  ? 329.937 349.578 470.616 1.00 123.45 ? 49  TYR L CD1 1 
ATOM 380  C CD2 . TYR A 1 49  ? 331.589 348.033 469.901 1.00 123.45 ? 49  TYR L CD2 1 
ATOM 381  C CE1 . TYR A 1 49  ? 329.370 349.564 469.361 1.00 123.45 ? 49  TYR L CE1 1 
ATOM 382  C CE2 . TYR A 1 49  ? 331.026 348.010 468.642 1.00 123.45 ? 49  TYR L CE2 1 
ATOM 383  C CZ  . TYR A 1 49  ? 329.915 348.777 468.380 1.00 123.45 ? 49  TYR L CZ  1 
ATOM 384  O OH  . TYR A 1 49  ? 329.345 348.762 467.130 1.00 123.45 ? 49  TYR L OH  1 
ATOM 385  N N   . ALA A 1 50  ? 334.656 349.785 471.640 1.00 122.11 ? 50  ALA L N   1 
ATOM 386  C CA  . ALA A 1 50  ? 335.835 350.000 470.787 1.00 122.11 ? 50  ALA L CA  1 
ATOM 387  C C   . ALA A 1 50  ? 336.296 351.454 470.782 1.00 122.11 ? 50  ALA L C   1 
ATOM 388  O O   . ALA A 1 50  ? 336.812 351.941 469.775 1.00 122.11 ? 50  ALA L O   1 
ATOM 389  C CB  . ALA A 1 50  ? 335.610 349.508 469.354 1.00 122.11 ? 50  ALA L CB  1 
ATOM 390  N N   . ALA A 1 51  ? 336.039 352.163 471.884 1.00 124.75 ? 51  ALA L N   1 
ATOM 391  C CA  . ALA A 1 51  ? 336.599 353.462 472.257 1.00 124.75 ? 51  ALA L CA  1 
ATOM 392  C C   . ALA A 1 51  ? 336.179 354.636 471.378 1.00 124.75 ? 51  ALA L C   1 
ATOM 393  O O   . ALA A 1 51  ? 336.504 355.781 471.700 1.00 124.75 ? 51  ALA L O   1 
ATOM 394  C CB  . ALA A 1 51  ? 338.129 353.397 472.303 1.00 124.75 ? 51  ALA L CB  1 
ATOM 395  N N   . THR A 1 52  ? 335.473 354.390 470.272 1.00 126.20 ? 52  THR L N   1 
ATOM 396  C CA  . THR A 1 52  ? 334.917 355.472 469.464 1.00 126.20 ? 52  THR L CA  1 
ATOM 397  C C   . THR A 1 52  ? 333.442 355.229 469.187 1.00 126.20 ? 52  THR L C   1 
ATOM 398  O O   . THR A 1 52  ? 332.643 356.168 469.175 1.00 126.20 ? 52  THR L O   1 
ATOM 399  C CB  . THR A 1 52  ? 335.637 355.631 468.116 1.00 126.20 ? 52  THR L CB  1 
ATOM 400  O OG1 . THR A 1 52  ? 335.206 354.600 467.219 1.00 126.20 ? 52  THR L OG1 1 
ATOM 401  C CG2 . THR A 1 52  ? 337.159 355.604 468.242 1.00 126.20 ? 52  THR L CG2 1 
ATOM 402  N N   . ASN A 1 53  ? 333.077 353.971 468.960 1.00 124.83 ? 53  ASN L N   1 
ATOM 403  C CA  . ASN A 1 53  ? 331.755 353.647 468.451 1.00 124.83 ? 53  ASN L CA  1 
ATOM 404  C C   . ASN A 1 53  ? 330.704 353.756 469.541 1.00 124.83 ? 53  ASN L C   1 
ATOM 405  O O   . ASN A 1 53  ? 330.937 353.385 470.693 1.00 124.83 ? 53  ASN L O   1 
ATOM 406  C CB  . ASN A 1 53  ? 331.741 352.238 467.866 1.00 124.83 ? 53  ASN L CB  1 
ATOM 407  C CG  . ASN A 1 53  ? 332.834 352.025 466.854 1.00 124.83 ? 53  ASN L CG  1 
ATOM 408  O OD1 . ASN A 1 53  ? 333.601 352.937 466.558 1.00 124.83 ? 53  ASN L OD1 1 
ATOM 409  N ND2 . ASN A 1 53  ? 332.916 350.816 466.315 1.00 124.83 ? 53  ASN L ND2 1 
ATOM 410  N N   . LEU A 1 54  ? 329.541 354.269 469.166 1.00 130.88 ? 54  LEU L N   1 
ATOM 411  C CA  . LEU A 1 54  ? 328.413 354.369 470.072 1.00 130.88 ? 54  LEU L CA  1 
ATOM 412  C C   . LEU A 1 54  ? 327.608 353.078 470.035 1.00 130.88 ? 54  LEU L C   1 
ATOM 413  O O   . LEU A 1 54  ? 327.698 352.289 469.095 1.00 130.88 ? 54  LEU L O   1 
ATOM 414  C CB  . LEU A 1 54  ? 327.526 355.552 469.693 1.00 130.88 ? 54  LEU L CB  1 
ATOM 415  C CG  . LEU A 1 54  ? 327.998 356.911 470.208 1.00 130.88 ? 54  LEU L CG  1 
ATOM 416  C CD1 . LEU A 1 54  ? 327.281 358.032 469.481 1.00 130.88 ? 54  LEU L CD1 1 
ATOM 417  C CD2 . LEU A 1 54  ? 327.810 357.035 471.704 1.00 130.88 ? 54  LEU L CD2 1 
ATOM 418  N N   . ALA A 1 55  ? 326.792 352.882 471.062 1.00 133.52 ? 55  ALA L N   1 
ATOM 419  C CA  . ALA A 1 55  ? 325.971 351.684 471.161 1.00 133.52 ? 55  ALA L CA  1 
ATOM 420  C C   . ALA A 1 55  ? 324.734 351.832 470.277 1.00 133.52 ? 55  ALA L C   1 
ATOM 421  O O   . ALA A 1 55  ? 324.643 352.722 469.427 1.00 133.52 ? 55  ALA L O   1 
ATOM 422  C CB  . ALA A 1 55  ? 325.610 351.408 472.615 1.00 133.52 ? 55  ALA L CB  1 
ATOM 423  N N   . ASP A 1 56  ? 323.760 350.943 470.462 1.00 136.86 ? 56  ASP L N   1 
ATOM 424  C CA  . ASP A 1 56  ? 322.596 350.926 469.583 1.00 136.86 ? 56  ASP L CA  1 
ATOM 425  C C   . ASP A 1 56  ? 321.652 352.083 469.884 1.00 136.86 ? 56  ASP L C   1 
ATOM 426  O O   . ASP A 1 56  ? 321.418 352.947 469.032 1.00 136.86 ? 56  ASP L O   1 
ATOM 427  C CB  . ASP A 1 56  ? 321.871 349.589 469.712 1.00 136.86 ? 56  ASP L CB  1 
ATOM 428  C CG  . ASP A 1 56  ? 321.281 349.126 468.403 1.00 136.86 ? 56  ASP L CG  1 
ATOM 429  O OD1 . ASP A 1 56  ? 321.790 349.546 467.345 1.00 136.86 ? 56  ASP L OD1 1 
ATOM 430  O OD2 . ASP A 1 56  ? 320.311 348.341 468.429 1.00 136.86 ? 56  ASP L OD2 1 
ATOM 431  N N   . GLY A 1 57  ? 321.107 352.124 471.095 1.00 144.03 ? 57  GLY L N   1 
ATOM 432  C CA  . GLY A 1 57  ? 320.149 353.138 471.478 1.00 144.03 ? 57  GLY L CA  1 
ATOM 433  C C   . GLY A 1 57  ? 320.705 354.292 472.279 1.00 144.03 ? 57  GLY L C   1 
ATOM 434  O O   . GLY A 1 57  ? 319.923 355.072 472.835 1.00 144.03 ? 57  GLY L O   1 
ATOM 435  N N   . VAL A 1 58  ? 322.019 354.432 472.359 1.00 145.52 ? 58  VAL L N   1 
ATOM 436  C CA  . VAL A 1 58  ? 322.625 355.505 473.148 1.00 145.52 ? 58  VAL L CA  1 
ATOM 437  C C   . VAL A 1 58  ? 322.561 356.800 472.342 1.00 145.52 ? 58  VAL L C   1 
ATOM 438  O O   . VAL A 1 58  ? 322.896 356.789 471.147 1.00 145.52 ? 58  VAL L O   1 
ATOM 439  C CB  . VAL A 1 58  ? 324.061 355.141 473.516 1.00 145.52 ? 58  VAL L CB  1 
ATOM 440  C CG1 . VAL A 1 58  ? 324.878 356.356 473.895 1.00 145.52 ? 58  VAL L CG1 1 
ATOM 441  C CG2 . VAL A 1 58  ? 324.057 354.149 474.658 1.00 145.52 ? 58  VAL L CG2 1 
ATOM 442  N N   . PRO A 1 59  ? 322.115 357.909 472.935 1.00 146.71 ? 59  PRO L N   1 
ATOM 443  C CA  . PRO A 1 59  ? 322.002 359.167 472.187 1.00 146.71 ? 59  PRO L CA  1 
ATOM 444  C C   . PRO A 1 59  ? 323.364 359.740 471.826 1.00 146.71 ? 59  PRO L C   1 
ATOM 445  O O   . PRO A 1 59  ? 324.409 359.324 472.326 1.00 146.71 ? 59  PRO L O   1 
ATOM 446  C CB  . PRO A 1 59  ? 321.252 360.092 473.150 1.00 146.71 ? 59  PRO L CB  1 
ATOM 447  C CG  . PRO A 1 59  ? 320.659 359.189 474.184 1.00 146.71 ? 59  PRO L CG  1 
ATOM 448  C CD  . PRO A 1 59  ? 321.592 358.038 474.303 1.00 146.71 ? 59  PRO L CD  1 
ATOM 449  N N   . SER A 1 60  ? 323.331 360.742 470.948 1.00 146.58 ? 60  SER L N   1 
ATOM 450  C CA  . SER A 1 60  ? 324.527 361.282 470.319 1.00 146.58 ? 60  SER L CA  1 
ATOM 451  C C   . SER A 1 60  ? 325.256 362.306 471.182 1.00 146.58 ? 60  SER L C   1 
ATOM 452  O O   . SER A 1 60  ? 326.193 362.950 470.698 1.00 146.58 ? 60  SER L O   1 
ATOM 453  C CB  . SER A 1 60  ? 324.171 361.910 468.972 1.00 146.58 ? 60  SER L CB  1 
ATOM 454  O OG  . SER A 1 60  ? 323.779 363.260 469.139 1.00 146.58 ? 60  SER L OG  1 
ATOM 455  N N   . ARG A 1 61  ? 324.853 362.477 472.438 1.00 152.31 ? 61  ARG L N   1 
ATOM 456  C CA  . ARG A 1 61  ? 325.579 363.375 473.322 1.00 152.31 ? 61  ARG L CA  1 
ATOM 457  C C   . ARG A 1 61  ? 326.901 362.787 473.785 1.00 152.31 ? 61  ARG L C   1 
ATOM 458  O O   . ARG A 1 61  ? 327.858 363.537 473.995 1.00 152.31 ? 61  ARG L O   1 
ATOM 459  C CB  . ARG A 1 61  ? 324.724 363.721 474.538 1.00 152.31 ? 61  ARG L CB  1 
ATOM 460  C CG  . ARG A 1 61  ? 323.326 364.173 474.193 1.00 152.31 ? 61  ARG L CG  1 
ATOM 461  C CD  . ARG A 1 61  ? 322.419 364.066 475.396 1.00 152.31 ? 61  ARG L CD  1 
ATOM 462  N NE  . ARG A 1 61  ? 322.042 362.687 475.682 1.00 152.31 ? 61  ARG L NE  1 
ATOM 463  C CZ  . ARG A 1 61  ? 321.536 362.285 476.841 1.00 152.31 ? 61  ARG L CZ  1 
ATOM 464  N NH1 . ARG A 1 61  ? 321.358 363.158 477.818 1.00 152.31 ? 61  ARG L NH1 1 
ATOM 465  N NH2 . ARG A 1 61  ? 321.213 361.015 477.027 1.00 152.31 ? 61  ARG L NH2 1 
ATOM 466  N N   . PHE A 1 62  ? 326.975 361.472 473.935 1.00 147.49 ? 62  PHE L N   1 
ATOM 467  C CA  . PHE A 1 62  ? 328.174 360.808 474.415 1.00 147.49 ? 62  PHE L CA  1 
ATOM 468  C C   . PHE A 1 62  ? 329.211 360.714 473.307 1.00 147.49 ? 62  PHE L C   1 
ATOM 469  O O   . PHE A 1 62  ? 328.880 360.628 472.123 1.00 147.49 ? 62  PHE L O   1 
ATOM 470  C CB  . PHE A 1 62  ? 327.846 359.408 474.929 1.00 147.49 ? 62  PHE L CB  1 
ATOM 471  C CG  . PHE A 1 62  ? 326.912 359.395 476.100 1.00 147.49 ? 62  PHE L CG  1 
ATOM 472  C CD1 . PHE A 1 62  ? 327.404 359.455 477.389 1.00 147.49 ? 62  PHE L CD1 1 
ATOM 473  C CD2 . PHE A 1 62  ? 325.544 359.311 475.912 1.00 147.49 ? 62  PHE L CD2 1 
ATOM 474  C CE1 . PHE A 1 62  ? 326.550 359.438 478.470 1.00 147.49 ? 62  PHE L CE1 1 
ATOM 475  C CE2 . PHE A 1 62  ? 324.685 359.294 476.989 1.00 147.49 ? 62  PHE L CE2 1 
ATOM 476  C CZ  . PHE A 1 62  ? 325.189 359.357 478.269 1.00 147.49 ? 62  PHE L CZ  1 
ATOM 477  N N   . SER A 1 63  ? 330.478 360.721 473.708 1.00 146.33 ? 63  SER L N   1 
ATOM 478  C CA  . SER A 1 63  ? 331.580 360.629 472.763 1.00 146.33 ? 63  SER L CA  1 
ATOM 479  C C   . SER A 1 63  ? 332.786 360.044 473.475 1.00 146.33 ? 63  SER L C   1 
ATOM 480  O O   . SER A 1 63  ? 333.057 360.397 474.625 1.00 146.33 ? 63  SER L O   1 
ATOM 481  C CB  . SER A 1 63  ? 331.925 362.001 472.180 1.00 146.33 ? 63  SER L CB  1 
ATOM 482  O OG  . SER A 1 63  ? 333.045 361.915 471.318 1.00 146.33 ? 63  SER L OG  1 
ATOM 483  N N   . GLY A 1 64  ? 333.499 359.153 472.795 1.00 141.09 ? 64  GLY L N   1 
ATOM 484  C CA  . GLY A 1 64  ? 334.720 358.567 473.313 1.00 141.09 ? 64  GLY L CA  1 
ATOM 485  C C   . GLY A 1 64  ? 335.860 358.789 472.334 1.00 141.09 ? 64  GLY L C   1 
ATOM 486  O O   . GLY A 1 64  ? 335.676 358.685 471.121 1.00 141.09 ? 64  GLY L O   1 
ATOM 487  N N   . SER A 1 65  ? 337.032 359.101 472.878 1.00 141.49 ? 65  SER L N   1 
ATOM 488  C CA  . SER A 1 65  ? 338.211 359.361 472.065 1.00 141.49 ? 65  SER L CA  1 
ATOM 489  C C   . SER A 1 65  ? 339.439 358.851 472.795 1.00 141.49 ? 65  SER L C   1 
ATOM 490  O O   . SER A 1 65  ? 339.469 358.842 474.029 1.00 141.49 ? 65  SER L O   1 
ATOM 491  C CB  . SER A 1 65  ? 338.369 360.856 471.766 1.00 141.49 ? 65  SER L CB  1 
ATOM 492  O OG  . SER A 1 65  ? 337.140 361.448 471.390 1.00 141.49 ? 65  SER L OG  1 
ATOM 493  N N   . GLY A 1 66  ? 340.436 358.432 472.043 1.00 137.37 ? 66  GLY L N   1 
ATOM 494  C CA  . GLY A 1 66  ? 341.694 358.006 472.619 1.00 137.37 ? 66  GLY L CA  1 
ATOM 495  C C   . GLY A 1 66  ? 342.258 356.819 471.876 1.00 137.37 ? 66  GLY L C   1 
ATOM 496  O O   . GLY A 1 66  ? 341.556 356.074 471.199 1.00 137.37 ? 66  GLY L O   1 
ATOM 497  N N   . SER A 1 67  ? 343.567 356.640 472.012 1.00 140.11 ? 67  SER L N   1 
ATOM 498  C CA  . SER A 1 67  ? 344.261 355.522 471.393 1.00 140.11 ? 67  SER L CA  1 
ATOM 499  C C   . SER A 1 67  ? 345.512 355.235 472.201 1.00 140.11 ? 67  SER L C   1 
ATOM 500  O O   . SER A 1 67  ? 346.047 356.119 472.873 1.00 140.11 ? 67  SER L O   1 
ATOM 501  C CB  . SER A 1 67  ? 344.625 355.815 469.937 1.00 140.11 ? 67  SER L CB  1 
ATOM 502  O OG  . SER A 1 67  ? 345.900 356.425 469.851 1.00 140.11 ? 67  SER L OG  1 
ATOM 503  N N   . GLY A 1 68  ? 345.977 353.994 472.124 1.00 138.44 ? 68  GLY L N   1 
ATOM 504  C CA  . GLY A 1 68  ? 347.136 353.604 472.896 1.00 138.44 ? 68  GLY L CA  1 
ATOM 505  C C   . GLY A 1 68  ? 346.772 353.233 474.316 1.00 138.44 ? 68  GLY L C   1 
ATOM 506  O O   . GLY A 1 68  ? 345.978 352.315 474.536 1.00 138.44 ? 68  GLY L O   1 
ATOM 507  N N   . THR A 1 69  ? 347.340 353.941 475.291 1.00 140.80 ? 69  THR L N   1 
ATOM 508  C CA  . THR A 1 69  ? 347.076 353.675 476.696 1.00 140.80 ? 69  THR L CA  1 
ATOM 509  C C   . THR A 1 69  ? 346.227 354.748 477.358 1.00 140.80 ? 69  THR L C   1 
ATOM 510  O O   . THR A 1 69  ? 345.894 354.610 478.538 1.00 140.80 ? 69  THR L O   1 
ATOM 511  C CB  . THR A 1 69  ? 348.389 353.532 477.469 1.00 140.80 ? 69  THR L CB  1 
ATOM 512  O OG1 . THR A 1 69  ? 348.971 354.826 477.655 1.00 140.80 ? 69  THR L OG1 1 
ATOM 513  C CG2 . THR A 1 69  ? 349.361 352.664 476.706 1.00 140.80 ? 69  THR L CG2 1 
ATOM 514  N N   . GLN A 1 70  ? 345.868 355.807 476.641 1.00 141.95 ? 70  GLN L N   1 
ATOM 515  C CA  . GLN A 1 70  ? 345.133 356.930 477.204 1.00 141.95 ? 70  GLN L CA  1 
ATOM 516  C C   . GLN A 1 70  ? 343.793 357.060 476.499 1.00 141.95 ? 70  GLN L C   1 
ATOM 517  O O   . GLN A 1 70  ? 343.746 357.161 475.270 1.00 141.95 ? 70  GLN L O   1 
ATOM 518  C CB  . GLN A 1 70  ? 345.934 358.224 477.063 1.00 141.95 ? 70  GLN L CB  1 
ATOM 519  C CG  . GLN A 1 70  ? 345.352 359.398 477.819 1.00 141.95 ? 70  GLN L CG  1 
ATOM 520  C CD  . GLN A 1 70  ? 345.687 359.357 479.294 1.00 141.95 ? 70  GLN L CD  1 
ATOM 521  O OE1 . GLN A 1 70  ? 346.668 358.737 479.701 1.00 141.95 ? 70  GLN L OE1 1 
ATOM 522  N NE2 . GLN A 1 70  ? 344.871 360.019 480.104 1.00 141.95 ? 70  GLN L NE2 1 
ATOM 523  N N   . TYR A 1 71  ? 342.709 357.061 477.271 1.00 137.48 ? 71  TYR L N   1 
ATOM 524  C CA  . TYR A 1 71  ? 341.368 357.130 476.711 1.00 137.48 ? 71  TYR L CA  1 
ATOM 525  C C   . TYR A 1 71  ? 340.527 358.103 477.520 1.00 137.48 ? 71  TYR L C   1 
ATOM 526  O O   . TYR A 1 71  ? 340.876 358.468 478.643 1.00 137.48 ? 71  TYR L O   1 
ATOM 527  C CB  . TYR A 1 71  ? 340.703 355.756 476.684 1.00 137.48 ? 71  TYR L CB  1 
ATOM 528  C CG  . TYR A 1 71  ? 341.465 354.743 475.871 1.00 137.48 ? 71  TYR L CG  1 
ATOM 529  C CD1 . TYR A 1 71  ? 341.364 354.720 474.490 1.00 137.48 ? 71  TYR L CD1 1 
ATOM 530  C CD2 . TYR A 1 71  ? 342.300 353.822 476.484 1.00 137.48 ? 71  TYR L CD2 1 
ATOM 531  C CE1 . TYR A 1 71  ? 342.064 353.802 473.742 1.00 137.48 ? 71  TYR L CE1 1 
ATOM 532  C CE2 . TYR A 1 71  ? 343.005 352.899 475.743 1.00 137.48 ? 71  TYR L CE2 1 
ATOM 533  C CZ  . TYR A 1 71  ? 342.882 352.896 474.373 1.00 137.48 ? 71  TYR L CZ  1 
ATOM 534  O OH  . TYR A 1 71  ? 343.583 351.984 473.626 1.00 137.48 ? 71  TYR L OH  1 
ATOM 535  N N   . SER A 1 72  ? 339.400 358.511 476.939 1.00 138.70 ? 72  SER L N   1 
ATOM 536  C CA  . SER A 1 72  ? 338.551 359.514 477.564 1.00 138.70 ? 72  SER L CA  1 
ATOM 537  C C   . SER A 1 72  ? 337.138 359.417 477.010 1.00 138.70 ? 72  SER L C   1 
ATOM 538  O O   . SER A 1 72  ? 336.929 358.961 475.885 1.00 138.70 ? 72  SER L O   1 
ATOM 539  C CB  . SER A 1 72  ? 339.096 360.925 477.337 1.00 138.70 ? 72  SER L CB  1 
ATOM 540  O OG  . SER A 1 72  ? 338.611 361.454 476.118 1.00 138.70 ? 72  SER L OG  1 
ATOM 541  N N   . LEU A 1 73  ? 336.177 359.862 477.814 1.00 141.54 ? 73  LEU L N   1 
ATOM 542  C CA  . LEU A 1 73  ? 334.778 359.937 477.426 1.00 141.54 ? 73  LEU L CA  1 
ATOM 543  C C   . LEU A 1 73  ? 334.235 361.318 477.763 1.00 141.54 ? 73  LEU L C   1 
ATOM 544  O O   . LEU A 1 73  ? 334.601 361.910 478.780 1.00 141.54 ? 73  LEU L O   1 
ATOM 545  C CB  . LEU A 1 73  ? 333.952 358.840 478.118 1.00 141.54 ? 73  LEU L CB  1 
ATOM 546  C CG  . LEU A 1 73  ? 332.471 358.656 477.773 1.00 141.54 ? 73  LEU L CG  1 
ATOM 547  C CD1 . LEU A 1 73  ? 332.123 357.200 477.750 1.00 141.54 ? 73  LEU L CD1 1 
ATOM 548  C CD2 . LEU A 1 73  ? 331.602 359.320 478.808 1.00 141.54 ? 73  LEU L CD2 1 
ATOM 549  N N   . LYS A 1 74  ? 333.352 361.827 476.907 1.00 147.80 ? 74  LYS L N   1 
ATOM 550  C CA  . LYS A 1 74  ? 332.840 363.184 477.035 1.00 147.80 ? 74  LYS L CA  1 
ATOM 551  C C   . LYS A 1 74  ? 331.324 363.203 476.935 1.00 147.80 ? 74  LYS L C   1 
ATOM 552  O O   . LYS A 1 74  ? 330.743 362.480 476.120 1.00 147.80 ? 74  LYS L O   1 
ATOM 553  C CB  . LYS A 1 74  ? 333.423 364.094 475.958 1.00 147.80 ? 74  LYS L CB  1 
ATOM 554  C CG  . LYS A 1 74  ? 334.743 364.732 476.322 1.00 147.80 ? 74  LYS L CG  1 
ATOM 555  C CD  . LYS A 1 74  ? 335.236 365.629 475.199 1.00 147.80 ? 74  LYS L CD  1 
ATOM 556  C CE  . LYS A 1 74  ? 334.190 366.664 474.810 1.00 147.80 ? 74  LYS L CE  1 
ATOM 557  N NZ  . LYS A 1 74  ? 334.550 367.372 473.551 1.00 147.80 ? 74  LYS L NZ  1 
ATOM 558  N N   . ILE A 1 75  ? 330.692 364.035 477.757 1.00 156.94 ? 75  ILE L N   1 
ATOM 559  C CA  . ILE A 1 75  ? 329.292 364.412 477.600 1.00 156.94 ? 75  ILE L CA  1 
ATOM 560  C C   . ILE A 1 75  ? 329.261 365.915 477.375 1.00 156.94 ? 75  ILE L C   1 
ATOM 561  O O   . ILE A 1 75  ? 329.747 366.681 478.215 1.00 156.94 ? 75  ILE L O   1 
ATOM 562  C CB  . ILE A 1 75  ? 328.439 364.032 478.821 1.00 156.94 ? 75  ILE L CB  1 
ATOM 563  C CG1 . ILE A 1 75  ? 328.375 362.519 479.018 1.00 156.94 ? 75  ILE L CG1 1 
ATOM 564  C CG2 . ILE A 1 75  ? 327.040 364.590 478.676 1.00 156.94 ? 75  ILE L CG2 1 
ATOM 565  C CD1 . ILE A 1 75  ? 329.335 361.983 480.038 1.00 156.94 ? 75  ILE L CD1 1 
ATOM 566  N N   . ASN A 1 76  ? 328.697 366.343 476.247 1.00 162.84 ? 76  ASN L N   1 
ATOM 567  C CA  . ASN A 1 76  ? 328.691 367.768 475.932 1.00 162.84 ? 76  ASN L CA  1 
ATOM 568  C C   . ASN A 1 76  ? 327.639 368.512 476.748 1.00 162.84 ? 76  ASN L C   1 
ATOM 569  O O   . ASN A 1 76  ? 327.882 369.622 477.231 1.00 162.84 ? 76  ASN L O   1 
ATOM 570  C CB  . ASN A 1 76  ? 328.463 367.976 474.435 1.00 162.84 ? 76  ASN L CB  1 
ATOM 571  C CG  . ASN A 1 76  ? 327.300 367.172 473.912 1.00 162.84 ? 76  ASN L CG  1 
ATOM 572  O OD1 . ASN A 1 76  ? 326.811 366.269 474.586 1.00 162.84 ? 76  ASN L OD1 1 
ATOM 573  N ND2 . ASN A 1 76  ? 326.843 367.497 472.708 1.00 162.84 ? 76  ASN L ND2 1 
ATOM 574  N N   . SER A 1 77  ? 326.459 367.919 476.910 1.00 164.76 ? 77  SER L N   1 
ATOM 575  C CA  . SER A 1 77  ? 325.379 368.531 477.675 1.00 164.76 ? 77  SER L CA  1 
ATOM 576  C C   . SER A 1 77  ? 324.758 367.472 478.568 1.00 164.76 ? 77  SER L C   1 
ATOM 577  O O   . SER A 1 77  ? 324.256 366.460 478.072 1.00 164.76 ? 77  SER L O   1 
ATOM 578  C CB  . SER A 1 77  ? 324.321 369.138 476.753 1.00 164.76 ? 77  SER L CB  1 
ATOM 579  O OG  . SER A 1 77  ? 323.344 368.174 476.410 1.00 164.76 ? 77  SER L OG  1 
ATOM 580  N N   . LEU A 1 78  ? 324.795 367.703 479.876 1.00 165.22 ? 78  LEU L N   1 
ATOM 581  C CA  . LEU A 1 78  ? 324.198 366.766 480.814 1.00 165.22 ? 78  LEU L CA  1 
ATOM 582  C C   . LEU A 1 78  ? 322.679 366.830 480.746 1.00 165.22 ? 78  LEU L C   1 
ATOM 583  O O   . LEU A 1 78  ? 322.094 367.814 480.289 1.00 165.22 ? 78  LEU L O   1 
ATOM 584  C CB  . LEU A 1 78  ? 324.651 367.064 482.242 1.00 165.22 ? 78  LEU L CB  1 
ATOM 585  C CG  . LEU A 1 78  ? 325.860 366.322 482.813 1.00 165.22 ? 78  LEU L CG  1 
ATOM 586  C CD1 . LEU A 1 78  ? 325.637 364.820 482.765 1.00 165.22 ? 78  LEU L CD1 1 
ATOM 587  C CD2 . LEU A 1 78  ? 327.145 366.705 482.107 1.00 165.22 ? 78  LEU L CD2 1 
ATOM 588  N N   . GLN A 1 79  ? 322.041 365.754 481.193 1.00 166.58 ? 79  GLN L N   1 
ATOM 589  C CA  . GLN A 1 79  ? 320.603 365.711 481.403 1.00 166.58 ? 79  GLN L CA  1 
ATOM 590  C C   . GLN A 1 79  ? 320.327 365.070 482.755 1.00 166.58 ? 79  GLN L C   1 
ATOM 591  O O   . GLN A 1 79  ? 321.245 364.675 483.478 1.00 166.58 ? 79  GLN L O   1 
ATOM 592  C CB  . GLN A 1 79  ? 319.886 364.954 480.281 1.00 166.58 ? 79  GLN L CB  1 
ATOM 593  C CG  . GLN A 1 79  ? 319.318 365.848 479.194 1.00 166.58 ? 79  GLN L CG  1 
ATOM 594  C CD  . GLN A 1 79  ? 320.350 366.251 478.166 1.00 166.58 ? 79  GLN L CD  1 
ATOM 595  O OE1 . GLN A 1 79  ? 321.442 365.693 478.116 1.00 166.58 ? 79  GLN L OE1 1 
ATOM 596  N NE2 . GLN A 1 79  ? 320.007 367.226 477.334 1.00 166.58 ? 79  GLN L NE2 1 
ATOM 597  N N   . SER A 1 80  ? 319.044 364.963 483.094 1.00 169.13 ? 80  SER L N   1 
ATOM 598  C CA  . SER A 1 80  ? 318.654 364.432 484.392 1.00 169.13 ? 80  SER L CA  1 
ATOM 599  C C   . SER A 1 80  ? 318.829 362.924 484.490 1.00 169.13 ? 80  SER L C   1 
ATOM 600  O O   . SER A 1 80  ? 318.914 362.398 485.603 1.00 169.13 ? 80  SER L O   1 
ATOM 601  C CB  . SER A 1 80  ? 317.200 364.796 484.690 1.00 169.13 ? 80  SER L CB  1 
ATOM 602  O OG  . SER A 1 80  ? 316.381 364.579 483.555 1.00 169.13 ? 80  SER L OG  1 
ATOM 603  N N   . GLU A 1 81  ? 318.883 362.223 483.364 1.00 166.90 ? 81  GLU L N   1 
ATOM 604  C CA  . GLU A 1 81  ? 318.999 360.773 483.354 1.00 166.90 ? 81  GLU L CA  1 
ATOM 605  C C   . GLU A 1 81  ? 320.423 360.294 483.115 1.00 166.90 ? 81  GLU L C   1 
ATOM 606  O O   . GLU A 1 81  ? 320.625 359.101 482.875 1.00 166.90 ? 81  GLU L O   1 
ATOM 607  C CB  . GLU A 1 81  ? 318.080 360.170 482.283 1.00 166.90 ? 81  GLU L CB  1 
ATOM 608  C CG  . GLU A 1 81  ? 318.311 360.697 480.869 1.00 166.90 ? 81  GLU L CG  1 
ATOM 609  C CD  . GLU A 1 81  ? 317.509 361.949 480.558 1.00 166.90 ? 81  GLU L CD  1 
ATOM 610  O OE1 . GLU A 1 81  ? 317.650 362.489 479.442 1.00 166.90 ? 81  GLU L OE1 1 
ATOM 611  O OE2 . GLU A 1 81  ? 316.739 362.392 481.434 1.00 166.90 ? 81  GLU L OE2 1 
ATOM 612  N N   . ASP A 1 82  ? 321.409 361.186 483.175 1.00 163.99 ? 82  ASP L N   1 
ATOM 613  C CA  . ASP A 1 82  ? 322.773 360.842 482.808 1.00 163.99 ? 82  ASP L CA  1 
ATOM 614  C C   . ASP A 1 82  ? 323.711 360.679 483.992 1.00 163.99 ? 82  ASP L C   1 
ATOM 615  O O   . ASP A 1 82  ? 324.913 360.492 483.779 1.00 163.99 ? 82  ASP L O   1 
ATOM 616  C CB  . ASP A 1 82  ? 323.344 361.898 481.853 1.00 163.99 ? 82  ASP L CB  1 
ATOM 617  C CG  . ASP A 1 82  ? 322.617 361.931 480.525 1.00 163.99 ? 82  ASP L CG  1 
ATOM 618  O OD1 . ASP A 1 82  ? 321.692 361.114 480.334 1.00 163.99 ? 82  ASP L OD1 1 
ATOM 619  O OD2 . ASP A 1 82  ? 322.969 362.769 479.669 1.00 163.99 ? 82  ASP L OD2 1 
ATOM 620  N N   . PHE A 1 83  ? 323.215 360.747 485.222 1.00 164.64 ? 83  PHE L N   1 
ATOM 621  C CA  . PHE A 1 83  ? 324.079 360.528 486.370 1.00 164.64 ? 83  PHE L CA  1 
ATOM 622  C C   . PHE A 1 83  ? 324.032 359.068 486.801 1.00 164.64 ? 83  PHE L C   1 
ATOM 623  O O   . PHE A 1 83  ? 323.120 358.319 486.444 1.00 164.64 ? 83  PHE L O   1 
ATOM 624  C CB  . PHE A 1 83  ? 323.695 361.426 487.548 1.00 164.64 ? 83  PHE L CB  1 
ATOM 625  C CG  . PHE A 1 83  ? 322.406 361.048 488.231 1.00 164.64 ? 83  PHE L CG  1 
ATOM 626  C CD1 . PHE A 1 83  ? 321.176 361.283 487.633 1.00 164.64 ? 83  PHE L CD1 1 
ATOM 627  C CD2 . PHE A 1 83  ? 322.431 360.470 489.491 1.00 164.64 ? 83  PHE L CD2 1 
ATOM 628  C CE1 . PHE A 1 83  ? 319.999 360.935 488.273 1.00 164.64 ? 83  PHE L CE1 1 
ATOM 629  C CE2 . PHE A 1 83  ? 321.259 360.120 490.136 1.00 164.64 ? 83  PHE L CE2 1 
ATOM 630  C CZ  . PHE A 1 83  ? 320.041 360.354 489.525 1.00 164.64 ? 83  PHE L CZ  1 
ATOM 631  N N   . GLY A 1 84  ? 325.026 358.675 487.576 1.00 158.00 ? 84  GLY L N   1 
ATOM 632  C CA  . GLY A 1 84  ? 325.166 357.305 488.010 1.00 158.00 ? 84  GLY L CA  1 
ATOM 633  C C   . GLY A 1 84  ? 326.633 356.947 488.113 1.00 158.00 ? 84  GLY L C   1 
ATOM 634  O O   . GLY A 1 84  ? 327.467 357.788 488.428 1.00 158.00 ? 84  GLY L O   1 
ATOM 635  N N   . SER A 1 85  ? 326.926 355.682 487.840 1.00 150.44 ? 85  SER L N   1 
ATOM 636  C CA  . SER A 1 85  ? 328.295 355.196 487.861 1.00 150.44 ? 85  SER L CA  1 
ATOM 637  C C   . SER A 1 85  ? 328.782 354.933 486.444 1.00 150.44 ? 85  SER L C   1 
ATOM 638  O O   . SER A 1 85  ? 327.994 354.592 485.558 1.00 150.44 ? 85  SER L O   1 
ATOM 639  C CB  . SER A 1 85  ? 328.396 353.923 488.698 1.00 150.44 ? 85  SER L CB  1 
ATOM 640  O OG  . SER A 1 85  ? 328.059 354.183 490.048 1.00 150.44 ? 85  SER L OG  1 
ATOM 641  N N   . TYR A 1 86  ? 330.086 355.098 486.233 1.00 147.43 ? 86  TYR L N   1 
ATOM 642  C CA  . TYR A 1 86  ? 330.703 354.881 484.930 1.00 147.43 ? 86  TYR L CA  1 
ATOM 643  C C   . TYR A 1 86  ? 331.988 354.089 485.109 1.00 147.43 ? 86  TYR L C   1 
ATOM 644  O O   . TYR A 1 86  ? 332.838 354.458 485.925 1.00 147.43 ? 86  TYR L O   1 
ATOM 645  C CB  . TYR A 1 86  ? 330.987 356.207 484.228 1.00 147.43 ? 86  TYR L CB  1 
ATOM 646  C CG  . TYR A 1 86  ? 329.743 356.911 483.764 1.00 147.43 ? 86  TYR L CG  1 
ATOM 647  C CD1 . TYR A 1 86  ? 329.179 356.616 482.534 1.00 147.43 ? 86  TYR L CD1 1 
ATOM 648  C CD2 . TYR A 1 86  ? 329.128 357.867 484.556 1.00 147.43 ? 86  TYR L CD2 1 
ATOM 649  C CE1 . TYR A 1 86  ? 328.039 357.257 482.103 1.00 147.43 ? 86  TYR L CE1 1 
ATOM 650  C CE2 . TYR A 1 86  ? 327.987 358.513 484.133 1.00 147.43 ? 86  TYR L CE2 1 
ATOM 651  C CZ  . TYR A 1 86  ? 327.449 358.204 482.906 1.00 147.43 ? 86  TYR L CZ  1 
ATOM 652  O OH  . TYR A 1 86  ? 326.311 358.840 482.475 1.00 147.43 ? 86  TYR L OH  1 
ATOM 653  N N   . PHE A 1 87  ? 332.129 353.010 484.346 1.00 143.84 ? 87  PHE L N   1 
ATOM 654  C CA  . PHE A 1 87  ? 333.292 352.142 484.404 1.00 143.84 ? 87  PHE L CA  1 
ATOM 655  C C   . PHE A 1 87  ? 333.858 351.945 483.007 1.00 143.84 ? 87  PHE L C   1 
ATOM 656  O O   . PHE A 1 87  ? 333.137 352.005 482.010 1.00 143.84 ? 87  PHE L O   1 
ATOM 657  C CB  . PHE A 1 87  ? 332.942 350.778 485.001 1.00 143.84 ? 87  PHE L CB  1 
ATOM 658  C CG  . PHE A 1 87  ? 332.092 350.856 486.222 1.00 143.84 ? 87  PHE L CG  1 
ATOM 659  C CD1 . PHE A 1 87  ? 332.657 351.131 487.452 1.00 143.84 ? 87  PHE L CD1 1 
ATOM 660  C CD2 . PHE A 1 87  ? 330.729 350.645 486.145 1.00 143.84 ? 87  PHE L CD2 1 
ATOM 661  C CE1 . PHE A 1 87  ? 331.876 351.203 488.588 1.00 143.84 ? 87  PHE L CE1 1 
ATOM 662  C CE2 . PHE A 1 87  ? 329.941 350.716 487.274 1.00 143.84 ? 87  PHE L CE2 1 
ATOM 663  C CZ  . PHE A 1 87  ? 330.516 350.994 488.497 1.00 143.84 ? 87  PHE L CZ  1 
ATOM 664  N N   . CYS A 1 88  ? 335.161 351.696 482.942 1.00 139.48 ? 88  CYS L N   1 
ATOM 665  C CA  . CYS A 1 88  ? 335.816 351.362 481.689 1.00 139.48 ? 88  CYS L CA  1 
ATOM 666  C C   . CYS A 1 88  ? 336.455 349.989 481.810 1.00 139.48 ? 88  CYS L C   1 
ATOM 667  O O   . CYS A 1 88  ? 336.967 349.622 482.871 1.00 139.48 ? 88  CYS L O   1 
ATOM 668  C CB  . CYS A 1 88  ? 336.846 352.433 481.288 1.00 139.48 ? 88  CYS L CB  1 
ATOM 669  S SG  . CYS A 1 88  ? 338.517 352.318 481.970 1.00 139.48 ? 88  CYS L SG  1 
ATOM 670  N N   . GLN A 1 89  ? 336.385 349.220 480.728 1.00 130.75 ? 89  GLN L N   1 
ATOM 671  C CA  . GLN A 1 89  ? 336.846 347.841 480.688 1.00 130.75 ? 89  GLN L CA  1 
ATOM 672  C C   . GLN A 1 89  ? 337.648 347.620 479.419 1.00 130.75 ? 89  GLN L C   1 
ATOM 673  O O   . GLN A 1 89  ? 337.235 348.055 478.343 1.00 130.75 ? 89  GLN L O   1 
ATOM 674  C CB  . GLN A 1 89  ? 335.666 346.863 480.710 1.00 130.75 ? 89  GLN L CB  1 
ATOM 675  C CG  . GLN A 1 89  ? 336.061 345.406 480.552 1.00 130.75 ? 89  GLN L CG  1 
ATOM 676  C CD  . GLN A 1 89  ? 334.967 344.564 479.952 1.00 130.75 ? 89  GLN L CD  1 
ATOM 677  O OE1 . GLN A 1 89  ? 333.920 345.073 479.575 1.00 130.75 ? 89  GLN L OE1 1 
ATOM 678  N NE2 . GLN A 1 89  ? 335.206 343.267 479.853 1.00 130.75 ? 89  GLN L NE2 1 
ATOM 679  N N   . HIS A 1 90  ? 338.792 346.955 479.534 1.00 128.73 ? 90  HIS L N   1 
ATOM 680  C CA  . HIS A 1 90  ? 339.498 346.481 478.357 1.00 128.73 ? 90  HIS L CA  1 
ATOM 681  C C   . HIS A 1 90  ? 339.039 345.062 478.058 1.00 128.73 ? 90  HIS L C   1 
ATOM 682  O O   . HIS A 1 90  ? 338.765 344.284 478.975 1.00 128.73 ? 90  HIS L O   1 
ATOM 683  C CB  . HIS A 1 90  ? 341.018 346.520 478.544 1.00 128.73 ? 90  HIS L CB  1 
ATOM 684  C CG  . HIS A 1 90  ? 341.555 345.442 479.430 1.00 128.73 ? 90  HIS L CG  1 
ATOM 685  N ND1 . HIS A 1 90  ? 341.964 344.219 478.945 1.00 128.73 ? 90  HIS L ND1 1 
ATOM 686  C CD2 . HIS A 1 90  ? 341.740 345.395 480.769 1.00 128.73 ? 90  HIS L CD2 1 
ATOM 687  C CE1 . HIS A 1 90  ? 342.381 343.467 479.945 1.00 128.73 ? 90  HIS L CE1 1 
ATOM 688  N NE2 . HIS A 1 90  ? 342.256 344.157 481.064 1.00 128.73 ? 90  HIS L NE2 1 
ATOM 689  N N   . PHE A 1 91  ? 338.926 344.732 476.778 1.00 126.80 ? 91  PHE L N   1 
ATOM 690  C CA  . PHE A 1 91  ? 338.689 343.356 476.369 1.00 126.80 ? 91  PHE L CA  1 
ATOM 691  C C   . PHE A 1 91  ? 339.806 342.882 475.455 1.00 126.80 ? 91  PHE L C   1 
ATOM 692  O O   . PHE A 1 91  ? 339.592 342.098 474.531 1.00 126.80 ? 91  PHE L O   1 
ATOM 693  C CB  . PHE A 1 91  ? 337.325 343.187 475.703 1.00 126.80 ? 91  PHE L CB  1 
ATOM 694  C CG  . PHE A 1 91  ? 336.960 344.282 474.748 1.00 126.80 ? 91  PHE L CG  1 
ATOM 695  C CD1 . PHE A 1 91  ? 337.469 344.304 473.462 1.00 126.80 ? 91  PHE L CD1 1 
ATOM 696  C CD2 . PHE A 1 91  ? 336.072 345.269 475.125 1.00 126.80 ? 91  PHE L CD2 1 
ATOM 697  C CE1 . PHE A 1 91  ? 337.121 345.304 472.583 1.00 126.80 ? 91  PHE L CE1 1 
ATOM 698  C CE2 . PHE A 1 91  ? 335.721 346.270 474.248 1.00 126.80 ? 91  PHE L CE2 1 
ATOM 699  C CZ  . PHE A 1 91  ? 336.248 346.287 472.977 1.00 126.80 ? 91  PHE L CZ  1 
ATOM 700  N N   . TRP A 1 92  ? 341.018 343.366 475.714 1.00 127.19 ? 92  TRP L N   1 
ATOM 701  C CA  . TRP A 1 92  ? 342.158 342.999 474.885 1.00 127.19 ? 92  TRP L CA  1 
ATOM 702  C C   . TRP A 1 92  ? 342.575 341.560 475.139 1.00 127.19 ? 92  TRP L C   1 
ATOM 703  O O   . TRP A 1 92  ? 342.728 340.774 474.201 1.00 127.19 ? 92  TRP L O   1 
ATOM 704  C CB  . TRP A 1 92  ? 343.320 343.955 475.146 1.00 127.19 ? 92  TRP L CB  1 
ATOM 705  C CG  . TRP A 1 92  ? 344.629 343.465 474.643 1.00 127.19 ? 92  TRP L CG  1 
ATOM 706  C CD1 . TRP A 1 92  ? 345.695 343.079 475.392 1.00 127.19 ? 92  TRP L CD1 1 
ATOM 707  C CD2 . TRP A 1 92  ? 345.023 343.318 473.278 1.00 127.19 ? 92  TRP L CD2 1 
ATOM 708  N NE1 . TRP A 1 92  ? 346.729 342.695 474.580 1.00 127.19 ? 92  TRP L NE1 1 
ATOM 709  C CE2 . TRP A 1 92  ? 346.341 342.833 473.275 1.00 127.19 ? 92  TRP L CE2 1 
ATOM 710  C CE3 . TRP A 1 92  ? 344.389 343.547 472.056 1.00 127.19 ? 92  TRP L CE3 1 
ATOM 711  C CZ2 . TRP A 1 92  ? 347.034 342.571 472.103 1.00 127.19 ? 92  TRP L CZ2 1 
ATOM 712  C CZ3 . TRP A 1 92  ? 345.078 343.288 470.896 1.00 127.19 ? 92  TRP L CZ3 1 
ATOM 713  C CH2 . TRP A 1 92  ? 346.386 342.802 470.926 1.00 127.19 ? 92  TRP L CH2 1 
ATOM 714  N N   . SER A 1 93  ? 342.731 341.185 476.401 1.00 132.22 ? 93  SER L N   1 
ATOM 715  C CA  . SER A 1 93  ? 343.243 339.863 476.720 1.00 132.22 ? 93  SER L CA  1 
ATOM 716  C C   . SER A 1 93  ? 342.715 339.446 478.077 1.00 132.22 ? 93  SER L C   1 
ATOM 717  O O   . SER A 1 93  ? 342.545 340.297 478.956 1.00 132.22 ? 93  SER L O   1 
ATOM 718  C CB  . SER A 1 93  ? 344.774 339.859 476.725 1.00 132.22 ? 93  SER L CB  1 
ATOM 719  O OG  . SER A 1 93  ? 345.259 338.620 477.191 1.00 132.22 ? 93  SER L OG  1 
ATOM 720  N N   . PRO A 1 94  ? 342.422 338.162 478.273 1.00 131.23 ? 94  PRO L N   1 
ATOM 721  C CA  . PRO A 1 94  ? 342.157 337.670 479.627 1.00 131.23 ? 94  PRO L CA  1 
ATOM 722  C C   . PRO A 1 94  ? 343.416 337.776 480.473 1.00 131.23 ? 94  PRO L C   1 
ATOM 723  O O   . PRO A 1 94  ? 344.513 337.463 480.006 1.00 131.23 ? 94  PRO L O   1 
ATOM 724  C CB  . PRO A 1 94  ? 341.746 336.211 479.404 1.00 131.23 ? 94  PRO L CB  1 
ATOM 725  C CG  . PRO A 1 94  ? 341.349 336.140 477.972 1.00 131.23 ? 94  PRO L CG  1 
ATOM 726  C CD  . PRO A 1 94  ? 342.218 337.117 477.260 1.00 131.23 ? 94  PRO L CD  1 
ATOM 727  N N   . VAL A 1 95  ? 343.271 338.230 481.721 1.00 132.48 ? 95  VAL L N   1 
ATOM 728  C CA  . VAL A 1 95  ? 342.004 338.492 482.405 1.00 132.48 ? 95  VAL L CA  1 
ATOM 729  C C   . VAL A 1 95  ? 341.501 339.927 482.205 1.00 132.48 ? 95  VAL L C   1 
ATOM 730  O O   . VAL A 1 95  ? 342.260 340.886 482.323 1.00 132.48 ? 95  VAL L O   1 
ATOM 731  C CB  . VAL A 1 95  ? 342.165 338.138 483.909 1.00 132.48 ? 95  VAL L CB  1 
ATOM 732  C CG1 . VAL A 1 95  ? 343.431 338.750 484.476 1.00 132.48 ? 95  VAL L CG1 1 
ATOM 733  C CG2 . VAL A 1 95  ? 340.975 338.595 484.723 1.00 132.48 ? 95  VAL L CG2 1 
ATOM 734  N N   . PHE A 1 96  ? 340.223 340.062 481.852 1.00 131.32 ? 96  PHE L N   1 
ATOM 735  C CA  . PHE A 1 96  ? 339.626 341.380 481.700 1.00 131.32 ? 96  PHE L CA  1 
ATOM 736  C C   . PHE A 1 96  ? 339.455 342.028 483.066 1.00 131.32 ? 96  PHE L C   1 
ATOM 737  O O   . PHE A 1 96  ? 338.892 341.431 483.986 1.00 131.32 ? 96  PHE L O   1 
ATOM 738  C CB  . PHE A 1 96  ? 338.265 341.296 481.011 1.00 131.32 ? 96  PHE L CB  1 
ATOM 739  C CG  . PHE A 1 96  ? 338.259 340.501 479.738 1.00 131.32 ? 96  PHE L CG  1 
ATOM 740  C CD1 . PHE A 1 96  ? 339.295 340.592 478.830 1.00 131.32 ? 96  PHE L CD1 1 
ATOM 741  C CD2 . PHE A 1 96  ? 337.194 339.673 479.443 1.00 131.32 ? 96  PHE L CD2 1 
ATOM 742  C CE1 . PHE A 1 96  ? 339.274 339.858 477.664 1.00 131.32 ? 96  PHE L CE1 1 
ATOM 743  C CE2 . PHE A 1 96  ? 337.169 338.942 478.278 1.00 131.32 ? 96  PHE L CE2 1 
ATOM 744  C CZ  . PHE A 1 96  ? 338.208 339.035 477.390 1.00 131.32 ? 96  PHE L CZ  1 
ATOM 745  N N   . THR A 1 97  ? 339.947 343.255 483.199 1.00 134.95 ? 97  THR L N   1 
ATOM 746  C CA  . THR A 1 97  ? 339.870 343.989 484.454 1.00 134.95 ? 97  THR L CA  1 
ATOM 747  C C   . THR A 1 97  ? 339.083 345.267 484.234 1.00 134.95 ? 97  THR L C   1 
ATOM 748  O O   . THR A 1 97  ? 339.384 346.034 483.317 1.00 134.95 ? 97  THR L O   1 
ATOM 749  C CB  . THR A 1 97  ? 341.260 344.328 484.998 1.00 134.95 ? 97  THR L CB  1 
ATOM 750  O OG1 . THR A 1 97  ? 341.912 345.238 484.107 1.00 134.95 ? 97  THR L OG1 1 
ATOM 751  C CG2 . THR A 1 97  ? 342.103 343.078 485.148 1.00 134.95 ? 97  THR L CG2 1 
ATOM 752  N N   . PHE A 1 98  ? 338.085 345.495 485.078 1.00 133.93 ? 98  PHE L N   1 
ATOM 753  C CA  . PHE A 1 98  ? 337.308 346.717 485.008 1.00 133.93 ? 98  PHE L CA  1 
ATOM 754  C C   . PHE A 1 98  ? 338.092 347.881 485.603 1.00 133.93 ? 98  PHE L C   1 
ATOM 755  O O   . PHE A 1 98  ? 339.161 347.714 486.192 1.00 133.93 ? 98  PHE L O   1 
ATOM 756  C CB  . PHE A 1 98  ? 335.985 346.555 485.746 1.00 133.93 ? 98  PHE L CB  1 
ATOM 757  C CG  . PHE A 1 98  ? 334.961 345.780 484.985 1.00 133.93 ? 98  PHE L CG  1 
ATOM 758  C CD1 . PHE A 1 98  ? 334.983 344.399 484.980 1.00 133.93 ? 98  PHE L CD1 1 
ATOM 759  C CD2 . PHE A 1 98  ? 333.969 346.434 484.281 1.00 133.93 ? 98  PHE L CD2 1 
ATOM 760  C CE1 . PHE A 1 98  ? 334.039 343.683 484.281 1.00 133.93 ? 98  PHE L CE1 1 
ATOM 761  C CE2 . PHE A 1 98  ? 333.021 345.724 483.580 1.00 133.93 ? 98  PHE L CE2 1 
ATOM 762  C CZ  . PHE A 1 98  ? 333.057 344.347 483.581 1.00 133.93 ? 98  PHE L CZ  1 
ATOM 763  N N   . GLY A 1 99  ? 337.544 349.074 485.444 1.00 143.85 ? 99  GLY L N   1 
ATOM 764  C CA  . GLY A 1 99  ? 338.119 350.236 486.078 1.00 143.85 ? 99  GLY L CA  1 
ATOM 765  C C   . GLY A 1 99  ? 337.673 350.371 487.516 1.00 143.85 ? 99  GLY L C   1 
ATOM 766  O O   . GLY A 1 99  ? 336.946 349.539 488.055 1.00 143.85 ? 99  GLY L O   1 
ATOM 767  N N   . ALA A 1 100 ? 338.126 351.450 488.150 1.00 148.56 ? 100 ALA L N   1 
ATOM 768  C CA  . ALA A 1 100 ? 337.736 351.706 489.530 1.00 148.56 ? 100 ALA L CA  1 
ATOM 769  C C   . ALA A 1 100 ? 336.298 352.197 489.618 1.00 148.56 ? 100 ALA L C   1 
ATOM 770  O O   . ALA A 1 100 ? 335.486 351.622 490.350 1.00 148.56 ? 100 ALA L O   1 
ATOM 771  C CB  . ALA A 1 100 ? 338.685 352.720 490.167 1.00 148.56 ? 100 ALA L CB  1 
ATOM 772  N N   . GLY A 1 101 ? 335.965 353.247 488.875 1.00 151.44 ? 101 GLY L N   1 
ATOM 773  C CA  . GLY A 1 101 ? 334.618 353.771 488.878 1.00 151.44 ? 101 GLY L CA  1 
ATOM 774  C C   . GLY A 1 101 ? 334.557 355.242 489.222 1.00 151.44 ? 101 GLY L C   1 
ATOM 775  O O   . GLY A 1 101 ? 335.386 355.743 489.985 1.00 151.44 ? 101 GLY L O   1 
ATOM 776  N N   . THR A 1 102 ? 333.580 355.945 488.661 1.00 153.21 ? 102 THR L N   1 
ATOM 777  C CA  . THR A 1 102 ? 333.379 357.355 488.968 1.00 153.21 ? 102 THR L CA  1 
ATOM 778  C C   . THR A 1 102 ? 331.889 357.584 489.151 1.00 153.21 ? 102 THR L C   1 
ATOM 779  O O   . THR A 1 102 ? 331.078 356.775 488.693 1.00 153.21 ? 102 THR L O   1 
ATOM 780  C CB  . THR A 1 102 ? 333.953 358.258 487.871 1.00 153.21 ? 102 THR L CB  1 
ATOM 781  O OG1 . THR A 1 102 ? 333.994 359.611 488.336 1.00 153.21 ? 102 THR L OG1 1 
ATOM 782  C CG2 . THR A 1 102 ? 333.127 358.187 486.605 1.00 153.21 ? 102 THR L CG2 1 
ATOM 783  N N   . LYS A 1 103 ? 331.530 358.647 489.860 1.00 160.03 ? 103 LYS L N   1 
ATOM 784  C CA  . LYS A 1 103 ? 330.140 358.941 490.167 1.00 160.03 ? 103 LYS L CA  1 
ATOM 785  C C   . LYS A 1 103 ? 329.808 360.387 489.836 1.00 160.03 ? 103 LYS L C   1 
ATOM 786  O O   . LYS A 1 103 ? 330.634 361.289 489.999 1.00 160.03 ? 103 LYS L O   1 
ATOM 787  C CB  . LYS A 1 103 ? 329.830 358.669 491.640 1.00 160.03 ? 103 LYS L CB  1 
ATOM 788  C CG  . LYS A 1 103 ? 329.799 357.196 492.004 1.00 160.03 ? 103 LYS L CG  1 
ATOM 789  C CD  . LYS A 1 103 ? 329.186 356.972 493.377 1.00 160.03 ? 103 LYS L CD  1 
ATOM 790  C CE  . LYS A 1 103 ? 327.818 357.626 493.503 1.00 160.03 ? 103 LYS L CE  1 
ATOM 791  N NZ  . LYS A 1 103 ? 326.885 357.195 492.425 1.00 160.03 ? 103 LYS L NZ  1 
ATOM 792  N N   . LEU A 1 104 ? 328.585 360.598 489.367 1.00 163.17 ? 104 LEU L N   1 
ATOM 793  C CA  . LEU A 1 104 ? 328.066 361.927 489.099 1.00 163.17 ? 104 LEU L CA  1 
ATOM 794  C C   . LEU A 1 104 ? 326.903 362.219 490.036 1.00 163.17 ? 104 LEU L C   1 
ATOM 795  O O   . LEU A 1 104 ? 325.926 361.468 490.094 1.00 163.17 ? 104 LEU L O   1 
ATOM 796  C CB  . LEU A 1 104 ? 327.623 362.061 487.641 1.00 163.17 ? 104 LEU L CB  1 
ATOM 797  C CG  . LEU A 1 104 ? 328.655 362.682 486.698 1.00 163.17 ? 104 LEU L CG  1 
ATOM 798  C CD1 . LEU A 1 104 ? 329.785 361.717 486.409 1.00 163.17 ? 104 LEU L CD1 1 
ATOM 799  C CD2 . LEU A 1 104 ? 327.995 363.122 485.405 1.00 163.17 ? 104 LEU L CD2 1 
ATOM 800  N N   . GLU A 1 105 ? 327.017 363.324 490.771 1.00 171.89 ? 105 GLU L N   1 
ATOM 801  C CA  . GLU A 1 105 ? 326.050 363.681 491.801 1.00 171.89 ? 105 GLU L CA  1 
ATOM 802  C C   . GLU A 1 105 ? 324.886 364.494 491.250 1.00 171.89 ? 105 GLU L C   1 
ATOM 803  O O   . GLU A 1 105 ? 323.760 364.355 491.740 1.00 171.89 ? 105 GLU L O   1 
ATOM 804  C CB  . GLU A 1 105 ? 326.752 364.458 492.923 1.00 171.89 ? 105 GLU L CB  1 
ATOM 805  C CG  . GLU A 1 105 ? 326.188 364.226 494.329 1.00 171.89 ? 105 GLU L CG  1 
ATOM 806  C CD  . GLU A 1 105 ? 324.874 364.947 494.586 1.00 171.89 ? 105 GLU L CD  1 
ATOM 807  O OE1 . GLU A 1 105 ? 324.042 364.419 495.355 1.00 171.89 ? 105 GLU L OE1 1 
ATOM 808  O OE2 . GLU A 1 105 ? 324.674 366.043 494.018 1.00 171.89 ? 105 GLU L OE2 1 
ATOM 809  N N   . LEU A 1 106 ? 325.145 365.318 490.230 1.00 170.15 ? 106 LEU L N   1 
ATOM 810  C CA  . LEU A 1 106 ? 324.189 366.260 489.636 1.00 170.15 ? 106 LEU L CA  1 
ATOM 811  C C   . LEU A 1 106 ? 323.603 367.199 490.693 1.00 170.15 ? 106 LEU L C   1 
ATOM 812  O O   . LEU A 1 106 ? 322.403 367.210 490.971 1.00 170.15 ? 106 LEU L O   1 
ATOM 813  C CB  . LEU A 1 106 ? 323.085 365.538 488.854 1.00 170.15 ? 106 LEU L CB  1 
ATOM 814  C CG  . LEU A 1 106 ? 323.403 365.092 487.425 1.00 170.15 ? 106 LEU L CG  1 
ATOM 815  C CD1 . LEU A 1 106 ? 322.125 364.730 486.698 1.00 170.15 ? 106 LEU L CD1 1 
ATOM 816  C CD2 . LEU A 1 106 ? 324.161 366.158 486.662 1.00 170.15 ? 106 LEU L CD2 1 
ATOM 817  N N   . LYS A 1 107 ? 324.489 367.993 491.285 1.00 170.60 ? 107 LYS L N   1 
ATOM 818  C CA  . LYS A 1 107 ? 324.092 368.968 492.291 1.00 170.60 ? 107 LYS L CA  1 
ATOM 819  C C   . LYS A 1 107 ? 323.578 370.249 491.645 1.00 170.60 ? 107 LYS L C   1 
ATOM 820  O O   . LYS A 1 107 ? 323.498 370.358 490.422 1.00 170.60 ? 107 LYS L O   1 
ATOM 821  C CB  . LYS A 1 107 ? 325.261 369.294 493.216 1.00 170.60 ? 107 LYS L CB  1 
ATOM 822  C CG  . LYS A 1 107 ? 326.434 369.954 492.513 1.00 170.60 ? 107 LYS L CG  1 
ATOM 823  C CD  . LYS A 1 107 ? 327.203 370.861 493.459 1.00 170.60 ? 107 LYS L CD  1 
ATOM 824  C CE  . LYS A 1 107 ? 327.618 370.128 494.727 1.00 170.60 ? 107 LYS L CE  1 
ATOM 825  N NZ  . LYS A 1 107 ? 328.081 371.065 495.788 1.00 170.60 ? 107 LYS L NZ  1 
ATOM 826  O OXT . LYS A 1 107 ? 323.233 371.208 492.336 1.00 170.60 ? 107 LYS L OXT 1 
ATOM 827  N N   . GLN B 2 1   ? 313.614 342.347 471.331 1.00 162.49 ? 1   GLN H N   1 
ATOM 828  C CA  . GLN B 2 1   ? 313.601 340.903 471.531 1.00 162.49 ? 1   GLN H CA  1 
ATOM 829  C C   . GLN B 2 1   ? 314.075 340.571 472.945 1.00 162.49 ? 1   GLN H C   1 
ATOM 830  O O   . GLN B 2 1   ? 315.038 341.158 473.437 1.00 162.49 ? 1   GLN H O   1 
ATOM 831  C CB  . GLN B 2 1   ? 314.472 340.213 470.477 1.00 162.49 ? 1   GLN H CB  1 
ATOM 832  C CG  . GLN B 2 1   ? 314.088 338.774 470.185 1.00 162.49 ? 1   GLN H CG  1 
ATOM 833  C CD  . GLN B 2 1   ? 314.646 337.808 471.204 1.00 162.49 ? 1   GLN H CD  1 
ATOM 834  O OE1 . GLN B 2 1   ? 315.845 337.810 471.482 1.00 162.49 ? 1   GLN H OE1 1 
ATOM 835  N NE2 . GLN B 2 1   ? 313.776 336.990 471.786 1.00 162.49 ? 1   GLN H NE2 1 
ATOM 836  N N   . VAL B 2 2   ? 313.392 339.626 473.580 1.00 163.85 ? 2   VAL H N   1 
ATOM 837  C CA  . VAL B 2 2   ? 313.588 339.323 474.989 1.00 163.85 ? 2   VAL H CA  1 
ATOM 838  C C   . VAL B 2 2   ? 314.911 338.577 475.153 1.00 163.85 ? 2   VAL H C   1 
ATOM 839  O O   . VAL B 2 2   ? 315.315 337.787 474.304 1.00 163.85 ? 2   VAL H O   1 
ATOM 840  C CB  . VAL B 2 2   ? 312.379 338.519 475.559 1.00 163.85 ? 2   VAL H CB  1 
ATOM 841  C CG1 . VAL B 2 2   ? 312.470 338.301 477.075 1.00 163.85 ? 2   VAL H CG1 1 
ATOM 842  C CG2 . VAL B 2 2   ? 311.067 339.205 475.192 1.00 163.85 ? 2   VAL H CG2 1 
ATOM 843  N N   . GLN B 2 3   ? 315.601 338.827 476.268 1.00 156.54 ? 3   GLN H N   1 
ATOM 844  C CA  . GLN B 2 3   ? 316.940 338.287 476.460 1.00 156.54 ? 3   GLN H CA  1 
ATOM 845  C C   . GLN B 2 3   ? 317.024 337.435 477.720 1.00 156.54 ? 3   GLN H C   1 
ATOM 846  O O   . GLN B 2 3   ? 315.999 337.080 478.308 1.00 156.54 ? 3   GLN H O   1 
ATOM 847  C CB  . GLN B 2 3   ? 317.968 339.417 476.505 1.00 156.54 ? 3   GLN H CB  1 
ATOM 848  C CG  . GLN B 2 3   ? 318.083 340.214 475.210 1.00 156.54 ? 3   GLN H CG  1 
ATOM 849  C CD  . GLN B 2 3   ? 318.096 339.339 473.969 1.00 156.54 ? 3   GLN H CD  1 
ATOM 850  O OE1 . GLN B 2 3   ? 318.937 338.451 473.826 1.00 156.54 ? 3   GLN H OE1 1 
ATOM 851  N NE2 . GLN B 2 3   ? 317.166 339.593 473.060 1.00 156.54 ? 3   GLN H NE2 1 
ATOM 852  N N   . LEU B 2 4   ? 318.242 337.097 478.125 1.00 150.36 ? 4   LEU H N   1 
ATOM 853  C CA  . LEU B 2 4   ? 318.518 336.044 479.090 1.00 150.36 ? 4   LEU H CA  1 
ATOM 854  C C   . LEU B 2 4   ? 318.093 336.418 480.510 1.00 150.36 ? 4   LEU H C   1 
ATOM 855  O O   . LEU B 2 4   ? 317.895 337.585 480.851 1.00 150.36 ? 4   LEU H O   1 
ATOM 856  C CB  . LEU B 2 4   ? 320.004 335.682 479.038 1.00 150.36 ? 4   LEU H CB  1 
ATOM 857  C CG  . LEU B 2 4   ? 321.072 336.778 479.129 1.00 150.36 ? 4   LEU H CG  1 
ATOM 858  C CD1 . LEU B 2 4   ? 321.485 337.102 480.547 1.00 150.36 ? 4   LEU H CD1 1 
ATOM 859  C CD2 . LEU B 2 4   ? 322.283 336.384 478.313 1.00 150.36 ? 4   LEU H CD2 1 
ATOM 860  N N   . LYS B 2 5   ? 317.967 335.385 481.344 1.00 152.21 ? 5   LYS H N   1 
ATOM 861  C CA  . LYS B 2 5   ? 317.552 335.519 482.732 1.00 152.21 ? 5   LYS H CA  1 
ATOM 862  C C   . LYS B 2 5   ? 318.104 334.332 483.508 1.00 152.21 ? 5   LYS H C   1 
ATOM 863  O O   . LYS B 2 5   ? 318.447 333.296 482.936 1.00 152.21 ? 5   LYS H O   1 
ATOM 864  C CB  . LYS B 2 5   ? 316.031 335.593 482.849 1.00 152.21 ? 5   LYS H CB  1 
ATOM 865  C CG  . LYS B 2 5   ? 315.325 334.364 482.313 1.00 152.21 ? 5   LYS H CG  1 
ATOM 866  C CD  . LYS B 2 5   ? 313.869 334.658 482.010 1.00 152.21 ? 5   LYS H CD  1 
ATOM 867  C CE  . LYS B 2 5   ? 313.737 335.692 480.908 1.00 152.21 ? 5   LYS H CE  1 
ATOM 868  N NZ  . LYS B 2 5   ? 312.313 336.018 480.634 1.00 152.21 ? 5   LYS H NZ  1 
ATOM 869  N N   . GLN B 2 6   ? 318.186 334.484 484.827 1.00 152.18 ? 6   GLN H N   1 
ATOM 870  C CA  . GLN B 2 6   ? 318.854 333.493 485.656 1.00 152.18 ? 6   GLN H CA  1 
ATOM 871  C C   . GLN B 2 6   ? 318.029 333.205 486.900 1.00 152.18 ? 6   GLN H C   1 
ATOM 872  O O   . GLN B 2 6   ? 317.064 333.905 487.213 1.00 152.18 ? 6   GLN H O   1 
ATOM 873  C CB  . GLN B 2 6   ? 320.258 333.955 486.048 1.00 152.18 ? 6   GLN H CB  1 
ATOM 874  C CG  . GLN B 2 6   ? 320.282 335.295 486.734 1.00 152.18 ? 6   GLN H CG  1 
ATOM 875  C CD  . GLN B 2 6   ? 321.657 335.911 486.733 1.00 152.18 ? 6   GLN H CD  1 
ATOM 876  O OE1 . GLN B 2 6   ? 322.468 335.640 487.614 1.00 152.18 ? 6   GLN H OE1 1 
ATOM 877  N NE2 . GLN B 2 6   ? 321.932 336.743 485.739 1.00 152.18 ? 6   GLN H NE2 1 
ATOM 878  N N   . SER B 2 7   ? 318.431 332.153 487.612 1.00 155.77 ? 7   SER H N   1 
ATOM 879  C CA  . SER B 2 7   ? 317.769 331.711 488.830 1.00 155.77 ? 7   SER H CA  1 
ATOM 880  C C   . SER B 2 7   ? 318.782 331.012 489.722 1.00 155.77 ? 7   SER H C   1 
ATOM 881  O O   . SER B 2 7   ? 319.423 330.047 489.302 1.00 155.77 ? 7   SER H O   1 
ATOM 882  C CB  . SER B 2 7   ? 316.610 330.765 488.514 1.00 155.77 ? 7   SER H CB  1 
ATOM 883  O OG  . SER B 2 7   ? 317.089 329.567 487.931 1.00 155.77 ? 7   SER H OG  1 
ATOM 884  N N   . GLY B 2 8   ? 318.910 331.488 490.959 1.00 160.58 ? 8   GLY H N   1 
ATOM 885  C CA  . GLY B 2 8   ? 319.950 331.015 491.843 1.00 160.58 ? 8   GLY H CA  1 
ATOM 886  C C   . GLY B 2 8   ? 319.450 330.579 493.206 1.00 160.58 ? 8   GLY H C   1 
ATOM 887  O O   . GLY B 2 8   ? 318.264 330.699 493.528 1.00 160.58 ? 8   GLY H O   1 
ATOM 888  N N   . PRO B 2 9   ? 320.357 330.059 494.038 1.00 164.41 ? 9   PRO H N   1 
ATOM 889  C CA  . PRO B 2 9   ? 319.936 329.518 495.339 1.00 164.41 ? 9   PRO H CA  1 
ATOM 890  C C   . PRO B 2 9   ? 319.654 330.579 496.386 1.00 164.41 ? 9   PRO H C   1 
ATOM 891  O O   . PRO B 2 9   ? 318.965 330.279 497.368 1.00 164.41 ? 9   PRO H O   1 
ATOM 892  C CB  . PRO B 2 9   ? 321.124 328.637 495.759 1.00 164.41 ? 9   PRO H CB  1 
ATOM 893  C CG  . PRO B 2 9   ? 322.032 328.575 494.560 1.00 164.41 ? 9   PRO H CG  1 
ATOM 894  C CD  . PRO B 2 9   ? 321.787 329.829 493.799 1.00 164.41 ? 9   PRO H CD  1 
ATOM 895  N N   . GLY B 2 10  ? 320.157 331.797 496.221 1.00 166.17 ? 10  GLY H N   1 
ATOM 896  C CA  . GLY B 2 10  ? 319.889 332.842 497.189 1.00 166.17 ? 10  GLY H CA  1 
ATOM 897  C C   . GLY B 2 10  ? 320.948 333.014 498.259 1.00 166.17 ? 10  GLY H C   1 
ATOM 898  O O   . GLY B 2 10  ? 321.525 334.096 498.382 1.00 166.17 ? 10  GLY H O   1 
ATOM 899  N N   . LEU B 2 11  ? 321.208 331.973 499.050 1.00 169.31 ? 11  LEU H N   1 
ATOM 900  C CA  . LEU B 2 11  ? 322.192 332.061 500.123 1.00 169.31 ? 11  LEU H CA  1 
ATOM 901  C C   . LEU B 2 11  ? 322.728 330.671 500.426 1.00 169.31 ? 11  LEU H C   1 
ATOM 902  O O   . LEU B 2 11  ? 321.988 329.687 500.337 1.00 169.31 ? 11  LEU H O   1 
ATOM 903  C CB  . LEU B 2 11  ? 321.582 332.708 501.378 1.00 169.31 ? 11  LEU H CB  1 
ATOM 904  C CG  . LEU B 2 11  ? 320.528 332.012 502.252 1.00 169.31 ? 11  LEU H CG  1 
ATOM 905  C CD1 . LEU B 2 11  ? 321.128 331.244 503.432 1.00 169.31 ? 11  LEU H CD1 1 
ATOM 906  C CD2 . LEU B 2 11  ? 319.498 333.018 502.740 1.00 169.31 ? 11  LEU H CD2 1 
ATOM 907  N N   . VAL B 2 12  ? 324.009 330.595 500.787 1.00 170.62 ? 12  VAL H N   1 
ATOM 908  C CA  . VAL B 2 12  ? 324.677 329.333 501.074 1.00 170.62 ? 12  VAL H CA  1 
ATOM 909  C C   . VAL B 2 12  ? 325.400 329.439 502.411 1.00 170.62 ? 12  VAL H C   1 
ATOM 910  O O   . VAL B 2 12  ? 325.653 330.528 502.927 1.00 170.62 ? 12  VAL H O   1 
ATOM 911  C CB  . VAL B 2 12  ? 325.672 328.924 499.967 1.00 170.62 ? 12  VAL H CB  1 
ATOM 912  C CG1 . VAL B 2 12  ? 324.953 328.647 498.656 1.00 170.62 ? 12  VAL H CG1 1 
ATOM 913  C CG2 . VAL B 2 12  ? 326.716 330.006 499.778 1.00 170.62 ? 12  VAL H CG2 1 
ATOM 914  N N   . GLN B 2 13  ? 325.720 328.275 502.972 1.00 171.63 ? 13  GLN H N   1 
ATOM 915  C CA  . GLN B 2 13  ? 326.586 328.189 504.132 1.00 171.63 ? 13  GLN H CA  1 
ATOM 916  C C   . GLN B 2 13  ? 328.042 328.339 503.693 1.00 171.63 ? 13  GLN H C   1 
ATOM 917  O O   . GLN B 2 13  ? 328.352 328.183 502.510 1.00 171.63 ? 13  GLN H O   1 
ATOM 918  C CB  . GLN B 2 13  ? 326.371 326.853 504.843 1.00 171.63 ? 13  GLN H CB  1 
ATOM 919  C CG  . GLN B 2 13  ? 325.057 326.755 505.591 1.00 171.63 ? 13  GLN H CG  1 
ATOM 920  C CD  . GLN B 2 13  ? 323.965 326.115 504.762 1.00 171.63 ? 13  GLN H CD  1 
ATOM 921  O OE1 . GLN B 2 13  ? 324.222 325.582 503.683 1.00 171.63 ? 13  GLN H OE1 1 
ATOM 922  N NE2 . GLN B 2 13  ? 322.737 326.162 505.263 1.00 171.63 ? 13  GLN H NE2 1 
ATOM 923  N N   . PRO B 2 14  ? 328.952 328.675 504.612 1.00 170.07 ? 14  PRO H N   1 
ATOM 924  C CA  . PRO B 2 14  ? 330.373 328.678 504.251 1.00 170.07 ? 14  PRO H CA  1 
ATOM 925  C C   . PRO B 2 14  ? 330.885 327.274 503.976 1.00 170.07 ? 14  PRO H C   1 
ATOM 926  O O   . PRO B 2 14  ? 330.350 326.286 504.486 1.00 170.07 ? 14  PRO H O   1 
ATOM 927  C CB  . PRO B 2 14  ? 331.054 329.284 505.482 1.00 170.07 ? 14  PRO H CB  1 
ATOM 928  C CG  . PRO B 2 14  ? 330.000 330.087 506.128 1.00 170.07 ? 14  PRO H CG  1 
ATOM 929  C CD  . PRO B 2 14  ? 328.739 329.313 505.923 1.00 170.07 ? 14  PRO H CD  1 
ATOM 930  N N   . SER B 2 15  ? 331.937 327.217 503.148 1.00 168.54 ? 15  SER H N   1 
ATOM 931  C CA  . SER B 2 15  ? 332.548 325.978 502.649 1.00 168.54 ? 15  SER H CA  1 
ATOM 932  C C   . SER B 2 15  ? 331.522 325.077 501.963 1.00 168.54 ? 15  SER H C   1 
ATOM 933  O O   . SER B 2 15  ? 331.506 323.860 502.150 1.00 168.54 ? 15  SER H O   1 
ATOM 934  C CB  . SER B 2 15  ? 333.283 325.224 503.760 1.00 168.54 ? 15  SER H CB  1 
ATOM 935  O OG  . SER B 2 15  ? 334.098 324.203 503.216 1.00 168.54 ? 15  SER H OG  1 
ATOM 936  N N   . GLN B 2 16  ? 330.654 325.687 501.163 1.00 168.83 ? 16  GLN H N   1 
ATOM 937  C CA  . GLN B 2 16  ? 329.636 324.975 500.407 1.00 168.83 ? 16  GLN H CA  1 
ATOM 938  C C   . GLN B 2 16  ? 329.735 325.364 498.942 1.00 168.83 ? 16  GLN H C   1 
ATOM 939  O O   . GLN B 2 16  ? 330.469 326.290 498.588 1.00 168.83 ? 16  GLN H O   1 
ATOM 940  C CB  . GLN B 2 16  ? 328.235 325.279 500.935 1.00 168.83 ? 16  GLN H CB  1 
ATOM 941  C CG  . GLN B 2 16  ? 327.948 324.663 502.286 1.00 168.83 ? 16  GLN H CG  1 
ATOM 942  C CD  . GLN B 2 16  ? 327.962 323.151 502.245 1.00 168.83 ? 16  GLN H CD  1 
ATOM 943  O OE1 . GLN B 2 16  ? 328.905 322.515 502.715 1.00 168.83 ? 16  GLN H OE1 1 
ATOM 944  N NE2 . GLN B 2 16  ? 326.912 322.565 501.683 1.00 168.83 ? 16  GLN H NE2 1 
ATOM 945  N N   . SER B 2 17  ? 329.008 324.646 498.094 1.00 165.85 ? 17  SER H N   1 
ATOM 946  C CA  . SER B 2 17  ? 329.027 324.910 496.665 1.00 165.85 ? 17  SER H CA  1 
ATOM 947  C C   . SER B 2 17  ? 327.897 325.851 496.266 1.00 165.85 ? 17  SER H C   1 
ATOM 948  O O   . SER B 2 17  ? 326.811 325.840 496.850 1.00 165.85 ? 17  SER H O   1 
ATOM 949  C CB  . SER B 2 17  ? 328.909 323.606 495.881 1.00 165.85 ? 17  SER H CB  1 
ATOM 950  O OG  . SER B 2 17  ? 327.552 323.228 495.741 1.00 165.85 ? 17  SER H OG  1 
ATOM 951  N N   . LEU B 2 18  ? 328.165 326.669 495.254 1.00 158.45 ? 18  LEU H N   1 
ATOM 952  C CA  . LEU B 2 18  ? 327.183 327.565 494.664 1.00 158.45 ? 18  LEU H CA  1 
ATOM 953  C C   . LEU B 2 18  ? 326.915 327.120 493.233 1.00 158.45 ? 18  LEU H C   1 
ATOM 954  O O   . LEU B 2 18  ? 327.834 326.692 492.533 1.00 158.45 ? 18  LEU H O   1 
ATOM 955  C CB  . LEU B 2 18  ? 327.685 329.011 494.694 1.00 158.45 ? 18  LEU H CB  1 
ATOM 956  C CG  . LEU B 2 18  ? 326.917 330.100 493.946 1.00 158.45 ? 18  LEU H CG  1 
ATOM 957  C CD1 . LEU B 2 18  ? 325.496 330.197 494.455 1.00 158.45 ? 18  LEU H CD1 1 
ATOM 958  C CD2 . LEU B 2 18  ? 327.624 331.429 494.090 1.00 158.45 ? 18  LEU H CD2 1 
ATOM 959  N N   . SER B 2 19  ? 325.657 327.199 492.802 1.00 154.45 ? 19  SER H N   1 
ATOM 960  C CA  . SER B 2 19  ? 325.283 326.770 491.457 1.00 154.45 ? 19  SER H CA  1 
ATOM 961  C C   . SER B 2 19  ? 324.146 327.645 490.951 1.00 154.45 ? 19  SER H C   1 
ATOM 962  O O   . SER B 2 19  ? 323.033 327.585 491.480 1.00 154.45 ? 19  SER H O   1 
ATOM 963  C CB  . SER B 2 19  ? 324.884 325.297 491.444 1.00 154.45 ? 19  SER H CB  1 
ATOM 964  O OG  . SER B 2 19  ? 326.014 324.474 491.667 1.00 154.45 ? 19  SER H OG  1 
ATOM 965  N N   . ILE B 2 20  ? 324.424 328.451 489.928 1.00 150.11 ? 20  ILE H N   1 
ATOM 966  C CA  . ILE B 2 20  ? 323.443 329.330 489.303 1.00 150.11 ? 20  ILE H CA  1 
ATOM 967  C C   . ILE B 2 20  ? 323.294 328.891 487.852 1.00 150.11 ? 20  ILE H C   1 
ATOM 968  O O   . ILE B 2 20  ? 324.268 328.449 487.234 1.00 150.11 ? 20  ILE H O   1 
ATOM 969  C CB  . ILE B 2 20  ? 323.870 330.808 489.398 1.00 150.11 ? 20  ILE H CB  1 
ATOM 970  C CG1 . ILE B 2 20  ? 324.282 331.149 490.826 1.00 150.11 ? 20  ILE H CG1 1 
ATOM 971  C CG2 . ILE B 2 20  ? 322.741 331.745 489.012 1.00 150.11 ? 20  ILE H CG2 1 
ATOM 972  C CD1 . ILE B 2 20  ? 324.896 332.514 490.967 1.00 150.11 ? 20  ILE H CD1 1 
ATOM 973  N N   . THR B 2 21  ? 322.080 328.995 487.316 1.00 146.65 ? 21  THR H N   1 
ATOM 974  C CA  . THR B 2 21  ? 321.786 328.622 485.939 1.00 146.65 ? 21  THR H CA  1 
ATOM 975  C C   . THR B 2 21  ? 321.210 329.826 485.210 1.00 146.65 ? 21  THR H C   1 
ATOM 976  O O   . THR B 2 21  ? 320.193 330.383 485.633 1.00 146.65 ? 21  THR H O   1 
ATOM 977  C CB  . THR B 2 21  ? 320.809 327.448 485.891 1.00 146.65 ? 21  THR H CB  1 
ATOM 978  O OG1 . THR B 2 21  ? 321.444 326.278 486.418 1.00 146.65 ? 21  THR H OG1 1 
ATOM 979  C CG2 . THR B 2 21  ? 320.362 327.181 484.466 1.00 146.65 ? 21  THR H CG2 1 
ATOM 980  N N   . CYS B 2 22  ? 321.858 330.225 484.122 1.00 149.71 ? 22  CYS H N   1 
ATOM 981  C CA  . CYS B 2 22  ? 321.402 331.329 483.289 1.00 149.71 ? 22  CYS H CA  1 
ATOM 982  C C   . CYS B 2 22  ? 320.807 330.767 482.005 1.00 149.71 ? 22  CYS H C   1 
ATOM 983  O O   . CYS B 2 22  ? 321.498 330.084 481.246 1.00 149.71 ? 22  CYS H O   1 
ATOM 984  C CB  . CYS B 2 22  ? 322.561 332.280 482.979 1.00 149.71 ? 22  CYS H CB  1 
ATOM 985  S SG  . CYS B 2 22  ? 322.113 333.869 482.235 1.00 149.71 ? 22  CYS H SG  1 
ATOM 986  N N   . THR B 2 23  ? 319.525 331.038 481.775 1.00 150.15 ? 23  THR H N   1 
ATOM 987  C CA  . THR B 2 23  ? 318.807 330.530 480.612 1.00 150.15 ? 23  THR H CA  1 
ATOM 988  C C   . THR B 2 23  ? 318.550 331.698 479.666 1.00 150.15 ? 23  THR H C   1 
ATOM 989  O O   . THR B 2 23  ? 318.198 332.793 480.114 1.00 150.15 ? 23  THR H O   1 
ATOM 990  C CB  . THR B 2 23  ? 317.502 329.861 481.047 1.00 150.15 ? 23  THR H CB  1 
ATOM 991  O OG1 . THR B 2 23  ? 317.803 328.792 481.951 1.00 150.15 ? 23  THR H OG1 1 
ATOM 992  C CG2 . THR B 2 23  ? 316.748 329.276 479.863 1.00 150.15 ? 23  THR H CG2 1 
ATOM 993  N N   . VAL B 2 24  ? 318.704 331.463 478.365 1.00 149.16 ? 24  VAL H N   1 
ATOM 994  C CA  . VAL B 2 24  ? 318.691 332.533 477.387 1.00 149.16 ? 24  VAL H CA  1 
ATOM 995  C C   . VAL B 2 24  ? 317.427 332.428 476.550 1.00 149.16 ? 24  VAL H C   1 
ATOM 996  O O   . VAL B 2 24  ? 316.648 331.478 476.660 1.00 149.16 ? 24  VAL H O   1 
ATOM 997  C CB  . VAL B 2 24  ? 319.933 332.482 476.479 1.00 149.16 ? 24  VAL H CB  1 
ATOM 998  C CG1 . VAL B 2 24  ? 321.195 332.657 477.298 1.00 149.16 ? 24  VAL H CG1 1 
ATOM 999  C CG2 . VAL B 2 24  ? 319.947 331.194 475.711 1.00 149.16 ? 24  VAL H CG2 1 
ATOM 1000 N N   . SER B 2 25  ? 317.229 333.417 475.683 1.00 153.80 ? 25  SER H N   1 
ATOM 1001 C CA  . SER B 2 25  ? 316.049 333.465 474.835 1.00 153.80 ? 25  SER H CA  1 
ATOM 1002 C C   . SER B 2 25  ? 316.353 334.295 473.599 1.00 153.80 ? 25  SER H C   1 
ATOM 1003 O O   . SER B 2 25  ? 316.925 335.383 473.692 1.00 153.80 ? 25  SER H O   1 
ATOM 1004 C CB  . SER B 2 25  ? 314.853 334.060 475.582 1.00 153.80 ? 25  SER H CB  1 
ATOM 1005 O OG  . SER B 2 25  ? 315.157 335.363 476.050 1.00 153.80 ? 25  SER H OG  1 
ATOM 1006 N N   . GLY B 2 26  ? 315.952 333.773 472.443 1.00 150.63 ? 26  GLY H N   1 
ATOM 1007 C CA  . GLY B 2 26  ? 316.010 334.511 471.204 1.00 150.63 ? 26  GLY H CA  1 
ATOM 1008 C C   . GLY B 2 26  ? 317.302 334.385 470.426 1.00 150.63 ? 26  GLY H C   1 
ATOM 1009 O O   . GLY B 2 26  ? 317.329 334.740 469.243 1.00 150.63 ? 26  GLY H O   1 
ATOM 1010 N N   . PHE B 2 27  ? 318.371 333.897 471.044 1.00 141.78 ? 27  PHE H N   1 
ATOM 1011 C CA  . PHE B 2 27  ? 319.614 333.674 470.325 1.00 141.78 ? 27  PHE H CA  1 
ATOM 1012 C C   . PHE B 2 27  ? 320.142 332.301 470.701 1.00 141.78 ? 27  PHE H C   1 
ATOM 1013 O O   . PHE B 2 27  ? 319.622 331.638 471.600 1.00 141.78 ? 27  PHE H O   1 
ATOM 1014 C CB  . PHE B 2 27  ? 320.647 334.773 470.610 1.00 141.78 ? 27  PHE H CB  1 
ATOM 1015 C CG  . PHE B 2 27  ? 321.088 334.853 472.047 1.00 141.78 ? 27  PHE H CG  1 
ATOM 1016 C CD1 . PHE B 2 27  ? 320.363 335.588 472.970 1.00 141.78 ? 27  PHE H CD1 1 
ATOM 1017 C CD2 . PHE B 2 27  ? 322.254 334.227 472.467 1.00 141.78 ? 27  PHE H CD2 1 
ATOM 1018 C CE1 . PHE B 2 27  ? 320.774 335.669 474.286 1.00 141.78 ? 27  PHE H CE1 1 
ATOM 1019 C CE2 . PHE B 2 27  ? 322.666 334.305 473.778 1.00 141.78 ? 27  PHE H CE2 1 
ATOM 1020 C CZ  . PHE B 2 27  ? 321.927 335.026 474.687 1.00 141.78 ? 27  PHE H CZ  1 
ATOM 1021 N N   . SER B 2 28  ? 321.191 331.882 470.008 1.00 135.36 ? 28  SER H N   1 
ATOM 1022 C CA  . SER B 2 28  ? 321.766 330.563 470.200 1.00 135.36 ? 28  SER H CA  1 
ATOM 1023 C C   . SER B 2 28  ? 323.081 330.665 470.957 1.00 135.36 ? 28  SER H C   1 
ATOM 1024 O O   . SER B 2 28  ? 323.701 331.728 471.017 1.00 135.36 ? 28  SER H O   1 
ATOM 1025 C CB  . SER B 2 28  ? 321.999 329.863 468.862 1.00 135.36 ? 28  SER H CB  1 
ATOM 1026 O OG  . SER B 2 28  ? 322.982 328.854 468.992 1.00 135.36 ? 28  SER H OG  1 
ATOM 1027 N N   . LEU B 2 29  ? 323.496 329.547 471.544 1.00 137.98 ? 29  LEU H N   1 
ATOM 1028 C CA  . LEU B 2 29  ? 324.811 329.484 472.161 1.00 137.98 ? 29  LEU H CA  1 
ATOM 1029 C C   . LEU B 2 29  ? 325.900 329.115 471.167 1.00 137.98 ? 29  LEU H C   1 
ATOM 1030 O O   . LEU B 2 29  ? 327.079 329.119 471.535 1.00 137.98 ? 29  LEU H O   1 
ATOM 1031 C CB  . LEU B 2 29  ? 324.832 328.479 473.314 1.00 137.98 ? 29  LEU H CB  1 
ATOM 1032 C CG  . LEU B 2 29  ? 324.410 328.933 474.714 1.00 137.98 ? 29  LEU H CG  1 
ATOM 1033 C CD1 . LEU B 2 29  ? 325.243 330.119 475.168 1.00 137.98 ? 29  LEU H CD1 1 
ATOM 1034 C CD2 . LEU B 2 29  ? 322.934 329.229 474.816 1.00 137.98 ? 29  LEU H CD2 1 
ATOM 1035 N N   . THR B 2 30  ? 325.538 328.792 469.930 1.00 133.18 ? 30  THR H N   1 
ATOM 1036 C CA  . THR B 2 30  ? 326.526 328.528 468.896 1.00 133.18 ? 30  THR H CA  1 
ATOM 1037 C C   . THR B 2 30  ? 327.002 329.795 468.207 1.00 133.18 ? 30  THR H C   1 
ATOM 1038 O O   . THR B 2 30  ? 327.853 329.714 467.317 1.00 133.18 ? 30  THR H O   1 
ATOM 1039 C CB  . THR B 2 30  ? 325.952 327.574 467.854 1.00 133.18 ? 30  THR H CB  1 
ATOM 1040 O OG1 . THR B 2 30  ? 324.819 328.186 467.229 1.00 133.18 ? 30  THR H OG1 1 
ATOM 1041 C CG2 . THR B 2 30  ? 325.517 326.280 468.510 1.00 133.18 ? 30  THR H CG2 1 
ATOM 1042 N N   . ASN B 2 31  ? 326.471 330.954 468.587 1.00 132.27 ? 31  ASN H N   1 
ATOM 1043 C CA  . ASN B 2 31  ? 326.850 332.214 467.974 1.00 132.27 ? 31  ASN H CA  1 
ATOM 1044 C C   . ASN B 2 31  ? 327.372 333.241 468.961 1.00 132.27 ? 31  ASN H C   1 
ATOM 1045 O O   . ASN B 2 31  ? 327.893 334.272 468.530 1.00 132.27 ? 31  ASN H O   1 
ATOM 1046 C CB  . ASN B 2 31  ? 325.656 332.819 467.225 1.00 132.27 ? 31  ASN H CB  1 
ATOM 1047 C CG  . ASN B 2 31  ? 325.368 332.107 465.929 1.00 132.27 ? 31  ASN H CG  1 
ATOM 1048 O OD1 . ASN B 2 31  ? 325.688 332.605 464.852 1.00 132.27 ? 31  ASN H OD1 1 
ATOM 1049 N ND2 . ASN B 2 31  ? 324.773 330.927 466.022 1.00 132.27 ? 31  ASN H ND2 1 
ATOM 1050 N N   . TYR B 2 32  ? 327.240 333.001 470.261 1.00 130.97 ? 32  TYR H N   1 
ATOM 1051 C CA  . TYR B 2 32  ? 327.636 333.969 471.268 1.00 130.97 ? 32  TYR H CA  1 
ATOM 1052 C C   . TYR B 2 32  ? 328.283 333.259 472.446 1.00 130.97 ? 32  TYR H C   1 
ATOM 1053 O O   . TYR B 2 32  ? 328.086 332.063 472.663 1.00 130.97 ? 32  TYR H O   1 
ATOM 1054 C CB  . TYR B 2 32  ? 326.440 334.787 471.755 1.00 130.97 ? 32  TYR H CB  1 
ATOM 1055 C CG  . TYR B 2 32  ? 325.757 335.582 470.672 1.00 130.97 ? 32  TYR H CG  1 
ATOM 1056 C CD1 . TYR B 2 32  ? 326.209 336.845 470.325 1.00 130.97 ? 32  TYR H CD1 1 
ATOM 1057 C CD2 . TYR B 2 32  ? 324.661 335.070 469.998 1.00 130.97 ? 32  TYR H CD2 1 
ATOM 1058 C CE1 . TYR B 2 32  ? 325.589 337.575 469.338 1.00 130.97 ? 32  TYR H CE1 1 
ATOM 1059 C CE2 . TYR B 2 32  ? 324.035 335.790 469.009 1.00 130.97 ? 32  TYR H CE2 1 
ATOM 1060 C CZ  . TYR B 2 32  ? 324.503 337.041 468.685 1.00 130.97 ? 32  TYR H CZ  1 
ATOM 1061 O OH  . TYR B 2 32  ? 323.878 337.762 467.698 1.00 130.97 ? 32  TYR H OH  1 
ATOM 1062 N N   . GLY B 2 33  ? 329.064 334.016 473.206 1.00 129.91 ? 33  GLY H N   1 
ATOM 1063 C CA  . GLY B 2 33  ? 329.616 333.525 474.450 1.00 129.91 ? 33  GLY H CA  1 
ATOM 1064 C C   . GLY B 2 33  ? 329.047 334.300 475.617 1.00 129.91 ? 33  GLY H C   1 
ATOM 1065 O O   . GLY B 2 33  ? 328.616 335.441 475.443 1.00 129.91 ? 33  GLY H O   1 
ATOM 1066 N N   . VAL B 2 34  ? 329.033 333.707 476.808 1.00 130.90 ? 34  VAL H N   1 
ATOM 1067 C CA  . VAL B 2 34  ? 328.422 334.312 477.985 1.00 130.90 ? 34  VAL H CA  1 
ATOM 1068 C C   . VAL B 2 34  ? 329.501 334.536 479.034 1.00 130.90 ? 34  VAL H C   1 
ATOM 1069 O O   . VAL B 2 34  ? 330.242 333.608 479.376 1.00 130.90 ? 34  VAL H O   1 
ATOM 1070 C CB  . VAL B 2 34  ? 327.288 333.436 478.544 1.00 130.90 ? 34  VAL H CB  1 
ATOM 1071 C CG1 . VAL B 2 34  ? 326.641 334.106 479.729 1.00 130.90 ? 34  VAL H CG1 1 
ATOM 1072 C CG2 . VAL B 2 34  ? 326.255 333.165 477.475 1.00 130.90 ? 34  VAL H CG2 1 
ATOM 1073 N N   . HIS B 2 35  ? 329.586 335.761 479.541 1.00 133.82 ? 35  HIS H N   1 
ATOM 1074 C CA  . HIS B 2 35  ? 330.551 336.133 480.563 1.00 133.82 ? 35  HIS H CA  1 
ATOM 1075 C C   . HIS B 2 35  ? 329.877 336.149 481.928 1.00 133.82 ? 35  HIS H C   1 
ATOM 1076 O O   . HIS B 2 35  ? 328.668 336.358 482.034 1.00 133.82 ? 35  HIS H O   1 
ATOM 1077 C CB  . HIS B 2 35  ? 331.151 337.513 480.282 1.00 133.82 ? 35  HIS H CB  1 
ATOM 1078 C CG  . HIS B 2 35  ? 331.886 337.613 478.982 1.00 133.82 ? 35  HIS H CG  1 
ATOM 1079 N ND1 . HIS B 2 35  ? 333.233 337.894 478.914 1.00 133.82 ? 35  HIS H ND1 1 
ATOM 1080 C CD2 . HIS B 2 35  ? 331.463 337.499 477.702 1.00 133.82 ? 35  HIS H CD2 1 
ATOM 1081 C CE1 . HIS B 2 35  ? 333.609 337.934 477.650 1.00 133.82 ? 35  HIS H CE1 1 
ATOM 1082 N NE2 . HIS B 2 35  ? 332.555 337.693 476.894 1.00 133.82 ? 35  HIS H NE2 1 
ATOM 1083 N N   . TRP B 2 36  ? 330.672 335.945 482.976 1.00 137.60 ? 36  TRP H N   1 
ATOM 1084 C CA  . TRP B 2 36  ? 330.178 335.948 484.351 1.00 137.60 ? 36  TRP H CA  1 
ATOM 1085 C C   . TRP B 2 36  ? 330.896 337.042 485.127 1.00 137.60 ? 36  TRP H C   1 
ATOM 1086 O O   . TRP B 2 36  ? 332.107 336.960 485.349 1.00 137.60 ? 36  TRP H O   1 
ATOM 1087 C CB  . TRP B 2 36  ? 330.380 334.588 485.007 1.00 137.60 ? 36  TRP H CB  1 
ATOM 1088 C CG  . TRP B 2 36  ? 329.533 333.526 484.410 1.00 137.60 ? 36  TRP H CG  1 
ATOM 1089 C CD1 . TRP B 2 36  ? 329.883 332.667 483.418 1.00 137.60 ? 36  TRP H CD1 1 
ATOM 1090 C CD2 . TRP B 2 36  ? 328.187 333.204 484.764 1.00 137.60 ? 36  TRP H CD2 1 
ATOM 1091 N NE1 . TRP B 2 36  ? 328.839 331.828 483.129 1.00 137.60 ? 36  TRP H NE1 1 
ATOM 1092 C CE2 . TRP B 2 36  ? 327.784 332.139 483.944 1.00 137.60 ? 36  TRP H CE2 1 
ATOM 1093 C CE3 . TRP B 2 36  ? 327.283 333.714 485.698 1.00 137.60 ? 36  TRP H CE3 1 
ATOM 1094 C CZ2 . TRP B 2 36  ? 326.519 331.573 484.027 1.00 137.60 ? 36  TRP H CZ2 1 
ATOM 1095 C CZ3 . TRP B 2 36  ? 326.030 333.150 485.781 1.00 137.60 ? 36  TRP H CZ3 1 
ATOM 1096 C CH2 . TRP B 2 36  ? 325.658 332.093 484.950 1.00 137.60 ? 36  TRP H CH2 1 
ATOM 1097 N N   . VAL B 2 37  ? 330.147 338.055 485.547 1.00 140.77 ? 37  VAL H N   1 
ATOM 1098 C CA  . VAL B 2 37  ? 330.696 339.238 486.192 1.00 140.77 ? 37  VAL H CA  1 
ATOM 1099 C C   . VAL B 2 37  ? 330.133 339.320 487.604 1.00 140.77 ? 37  VAL H C   1 
ATOM 1100 O O   . VAL B 2 37  ? 328.940 339.098 487.829 1.00 140.77 ? 37  VAL H O   1 
ATOM 1101 C CB  . VAL B 2 37  ? 330.365 340.508 485.373 1.00 140.77 ? 37  VAL H CB  1 
ATOM 1102 C CG1 . VAL B 2 37  ? 330.854 341.771 486.057 1.00 140.77 ? 37  VAL H CG1 1 
ATOM 1103 C CG2 . VAL B 2 37  ? 330.954 340.408 483.982 1.00 140.77 ? 37  VAL H CG2 1 
ATOM 1104 N N   . ARG B 2 38  ? 331.004 339.633 488.563 1.00 145.40 ? 38  ARG H N   1 
ATOM 1105 C CA  . ARG B 2 38  ? 330.640 339.717 489.973 1.00 145.40 ? 38  ARG H CA  1 
ATOM 1106 C C   . ARG B 2 38  ? 330.771 341.161 490.436 1.00 145.40 ? 38  ARG H C   1 
ATOM 1107 O O   . ARG B 2 38  ? 331.858 341.741 490.364 1.00 145.40 ? 38  ARG H O   1 
ATOM 1108 C CB  . ARG B 2 38  ? 331.522 338.799 490.813 1.00 145.40 ? 38  ARG H CB  1 
ATOM 1109 C CG  . ARG B 2 38  ? 331.403 339.037 492.291 1.00 145.40 ? 38  ARG H CG  1 
ATOM 1110 C CD  . ARG B 2 38  ? 331.959 337.876 493.077 1.00 145.40 ? 38  ARG H CD  1 
ATOM 1111 N NE  . ARG B 2 38  ? 333.366 338.061 493.405 1.00 145.40 ? 38  ARG H NE  1 
ATOM 1112 C CZ  . ARG B 2 38  ? 334.041 337.272 494.230 1.00 145.40 ? 38  ARG H CZ  1 
ATOM 1113 N NH1 . ARG B 2 38  ? 333.436 336.244 494.806 1.00 145.40 ? 38  ARG H NH1 1 
ATOM 1114 N NH2 . ARG B 2 38  ? 335.319 337.509 494.478 1.00 145.40 ? 38  ARG H NH2 1 
ATOM 1115 N N   . GLN B 2 39  ? 329.670 341.738 490.910 1.00 149.41 ? 39  GLN H N   1 
ATOM 1116 C CA  . GLN B 2 39  ? 329.656 343.108 491.414 1.00 149.41 ? 39  GLN H CA  1 
ATOM 1117 C C   . GLN B 2 39  ? 329.785 343.072 492.931 1.00 149.41 ? 39  GLN H C   1 
ATOM 1118 O O   . GLN B 2 39  ? 328.912 342.542 493.624 1.00 149.41 ? 39  GLN H O   1 
ATOM 1119 C CB  . GLN B 2 39  ? 328.380 343.827 490.985 1.00 149.41 ? 39  GLN H CB  1 
ATOM 1120 C CG  . GLN B 2 39  ? 328.053 345.082 491.778 1.00 149.41 ? 39  GLN H CG  1 
ATOM 1121 C CD  . GLN B 2 39  ? 328.740 346.311 491.240 1.00 149.41 ? 39  GLN H CD  1 
ATOM 1122 O OE1 . GLN B 2 39  ? 328.282 346.918 490.274 1.00 149.41 ? 39  GLN H OE1 1 
ATOM 1123 N NE2 . GLN B 2 39  ? 329.845 346.691 491.866 1.00 149.41 ? 39  GLN H NE2 1 
ATOM 1124 N N   . SER B 2 40  ? 330.852 343.618 493.434 1.00 152.24 ? 40  SER H N   1 
ATOM 1125 C CA  . SER B 2 40  ? 331.097 343.630 494.864 1.00 152.24 ? 40  SER H CA  1 
ATOM 1126 C C   . SER B 2 40  ? 331.117 345.059 495.392 1.00 152.24 ? 40  SER H C   1 
ATOM 1127 O O   . SER B 2 40  ? 331.591 345.971 494.711 1.00 152.24 ? 40  SER H O   1 
ATOM 1128 C CB  . SER B 2 40  ? 332.430 342.952 495.187 1.00 152.24 ? 40  SER H CB  1 
ATOM 1129 O OG  . SER B 2 40  ? 332.707 343.001 496.574 1.00 152.24 ? 40  SER H OG  1 
ATOM 1130 N N   . PRO B 2 41  ? 330.601 345.290 496.602 1.00 156.21 ? 41  PRO H N   1 
ATOM 1131 C CA  . PRO B 2 41  ? 330.658 346.653 497.152 1.00 156.21 ? 41  PRO H CA  1 
ATOM 1132 C C   . PRO B 2 41  ? 332.037 347.032 497.654 1.00 156.21 ? 41  PRO H C   1 
ATOM 1133 O O   . PRO B 2 41  ? 332.342 348.225 497.768 1.00 156.21 ? 41  PRO H O   1 
ATOM 1134 C CB  . PRO B 2 41  ? 329.628 346.611 498.287 1.00 156.21 ? 41  PRO H CB  1 
ATOM 1135 C CG  . PRO B 2 41  ? 329.618 345.189 498.717 1.00 156.21 ? 41  PRO H CG  1 
ATOM 1136 C CD  . PRO B 2 41  ? 329.846 344.374 497.474 1.00 156.21 ? 41  PRO H CD  1 
ATOM 1137 N N   . GLY B 2 42  ? 332.881 346.052 497.957 1.00 154.79 ? 42  GLY H N   1 
ATOM 1138 C CA  . GLY B 2 42  ? 334.195 346.339 498.493 1.00 154.79 ? 42  GLY H CA  1 
ATOM 1139 C C   . GLY B 2 42  ? 335.279 346.442 497.441 1.00 154.79 ? 42  GLY H C   1 
ATOM 1140 O O   . GLY B 2 42  ? 336.144 347.318 497.520 1.00 154.79 ? 42  GLY H O   1 
ATOM 1141 N N   . LYS B 2 43  ? 335.243 345.556 496.447 1.00 152.40 ? 43  LYS H N   1 
ATOM 1142 C CA  . LYS B 2 43  ? 336.273 345.510 495.421 1.00 152.40 ? 43  LYS H CA  1 
ATOM 1143 C C   . LYS B 2 43  ? 335.785 345.955 494.052 1.00 152.40 ? 43  LYS H C   1 
ATOM 1144 O O   . LYS B 2 43  ? 336.549 345.870 493.085 1.00 152.40 ? 43  LYS H O   1 
ATOM 1145 C CB  . LYS B 2 43  ? 336.854 344.095 495.317 1.00 152.40 ? 43  LYS H CB  1 
ATOM 1146 C CG  . LYS B 2 43  ? 337.413 343.568 496.623 1.00 152.40 ? 43  LYS H CG  1 
ATOM 1147 C CD  . LYS B 2 43  ? 337.235 342.065 496.728 1.00 152.40 ? 43  LYS H CD  1 
ATOM 1148 C CE  . LYS B 2 43  ? 335.765 341.690 496.799 1.00 152.40 ? 43  LYS H CE  1 
ATOM 1149 N NZ  . LYS B 2 43  ? 335.110 342.227 498.023 1.00 152.40 ? 43  LYS H NZ  1 
ATOM 1150 N N   . GLY B 2 44  ? 334.547 346.427 493.939 1.00 147.59 ? 44  GLY H N   1 
ATOM 1151 C CA  . GLY B 2 44  ? 334.052 346.847 492.646 1.00 147.59 ? 44  GLY H CA  1 
ATOM 1152 C C   . GLY B 2 44  ? 333.704 345.662 491.764 1.00 147.59 ? 44  GLY H C   1 
ATOM 1153 O O   . GLY B 2 44  ? 333.528 344.532 492.226 1.00 147.59 ? 44  GLY H O   1 
ATOM 1154 N N   . LEU B 2 45  ? 333.610 345.928 490.468 1.00 140.50 ? 45  LEU H N   1 
ATOM 1155 C CA  . LEU B 2 45  ? 333.279 344.903 489.494 1.00 140.50 ? 45  LEU H CA  1 
ATOM 1156 C C   . LEU B 2 45  ? 334.506 344.062 489.183 1.00 140.50 ? 45  LEU H C   1 
ATOM 1157 O O   . LEU B 2 45  ? 335.636 344.555 489.214 1.00 140.50 ? 45  LEU H O   1 
ATOM 1158 C CB  . LEU B 2 45  ? 332.743 345.534 488.212 1.00 140.50 ? 45  LEU H CB  1 
ATOM 1159 C CG  . LEU B 2 45  ? 331.319 346.075 488.266 1.00 140.50 ? 45  LEU H CG  1 
ATOM 1160 C CD1 . LEU B 2 45  ? 331.138 347.162 487.234 1.00 140.50 ? 45  LEU H CD1 1 
ATOM 1161 C CD2 . LEU B 2 45  ? 330.340 344.956 488.024 1.00 140.50 ? 45  LEU H CD2 1 
ATOM 1162 N N   . GLU B 2 46  ? 334.277 342.789 488.879 1.00 142.55 ? 46  GLU H N   1 
ATOM 1163 C CA  . GLU B 2 46  ? 335.359 341.889 488.520 1.00 142.55 ? 46  GLU H CA  1 
ATOM 1164 C C   . GLU B 2 46  ? 334.821 340.802 487.603 1.00 142.55 ? 46  GLU H C   1 
ATOM 1165 O O   . GLU B 2 46  ? 333.683 340.352 487.746 1.00 142.55 ? 46  GLU H O   1 
ATOM 1166 C CB  . GLU B 2 46  ? 336.013 341.280 489.762 1.00 142.55 ? 46  GLU H CB  1 
ATOM 1167 C CG  . GLU B 2 46  ? 335.027 340.713 490.757 1.00 142.55 ? 46  GLU H CG  1 
ATOM 1168 C CD  . GLU B 2 46  ? 335.660 340.433 492.102 1.00 142.55 ? 46  GLU H CD  1 
ATOM 1169 O OE1 . GLU B 2 46  ? 336.886 340.631 492.236 1.00 142.55 ? 46  GLU H OE1 1 
ATOM 1170 O OE2 . GLU B 2 46  ? 334.931 340.022 493.028 1.00 142.55 ? 46  GLU H OE2 1 
ATOM 1171 N N   . TRP B 2 47  ? 335.654 340.397 486.654 1.00 135.26 ? 47  TRP H N   1 
ATOM 1172 C CA  . TRP B 2 47  ? 335.290 339.420 485.641 1.00 135.26 ? 47  TRP H CA  1 
ATOM 1173 C C   . TRP B 2 47  ? 335.751 338.047 486.109 1.00 135.26 ? 47  TRP H C   1 
ATOM 1174 O O   . TRP B 2 47  ? 336.935 337.855 486.401 1.00 135.26 ? 47  TRP H O   1 
ATOM 1175 C CB  . TRP B 2 47  ? 335.924 339.796 484.303 1.00 135.26 ? 47  TRP H CB  1 
ATOM 1176 C CG  . TRP B 2 47  ? 335.752 338.799 483.217 1.00 135.26 ? 47  TRP H CG  1 
ATOM 1177 C CD1 . TRP B 2 47  ? 334.709 338.706 482.353 1.00 135.26 ? 47  TRP H CD1 1 
ATOM 1178 C CD2 . TRP B 2 47  ? 336.670 337.766 482.852 1.00 135.26 ? 47  TRP H CD2 1 
ATOM 1179 N NE1 . TRP B 2 47  ? 334.910 337.669 481.481 1.00 135.26 ? 47  TRP H NE1 1 
ATOM 1180 C CE2 . TRP B 2 47  ? 336.110 337.076 481.768 1.00 135.26 ? 47  TRP H CE2 1 
ATOM 1181 C CE3 . TRP B 2 47  ? 337.909 337.354 483.344 1.00 135.26 ? 47  TRP H CE3 1 
ATOM 1182 C CZ2 . TRP B 2 47  ? 336.746 335.997 481.167 1.00 135.26 ? 47  TRP H CZ2 1 
ATOM 1183 C CZ3 . TRP B 2 47  ? 338.537 336.287 482.745 1.00 135.26 ? 47  TRP H CZ3 1 
ATOM 1184 C CH2 . TRP B 2 47  ? 337.957 335.619 481.670 1.00 135.26 ? 47  TRP H CH2 1 
ATOM 1185 N N   . LEU B 2 48  ? 334.819 337.100 486.191 1.00 136.71 ? 48  LEU H N   1 
ATOM 1186 C CA  . LEU B 2 48  ? 335.127 335.795 486.762 1.00 136.71 ? 48  LEU H CA  1 
ATOM 1187 C C   . LEU B 2 48  ? 335.536 334.776 485.707 1.00 136.71 ? 48  LEU H C   1 
ATOM 1188 O O   . LEU B 2 48  ? 336.545 334.087 485.868 1.00 136.71 ? 48  LEU H O   1 
ATOM 1189 C CB  . LEU B 2 48  ? 333.927 335.269 487.548 1.00 136.71 ? 48  LEU H CB  1 
ATOM 1190 C CG  . LEU B 2 48  ? 333.661 335.919 488.901 1.00 136.71 ? 48  LEU H CG  1 
ATOM 1191 C CD1 . LEU B 2 48  ? 332.474 335.257 489.554 1.00 136.71 ? 48  LEU H CD1 1 
ATOM 1192 C CD2 . LEU B 2 48  ? 334.882 335.817 489.786 1.00 136.71 ? 48  LEU H CD2 1 
ATOM 1193 N N   . GLY B 2 49  ? 334.762 334.653 484.640 1.00 134.47 ? 49  GLY H N   1 
ATOM 1194 C CA  . GLY B 2 49  ? 335.077 333.665 483.633 1.00 134.47 ? 49  GLY H CA  1 
ATOM 1195 C C   . GLY B 2 49  ? 334.171 333.805 482.435 1.00 134.47 ? 49  GLY H C   1 
ATOM 1196 O O   . GLY B 2 49  ? 333.258 334.631 482.414 1.00 134.47 ? 49  GLY H O   1 
ATOM 1197 N N   . VAL B 2 50  ? 334.433 332.975 481.432 1.00 133.28 ? 50  VAL H N   1 
ATOM 1198 C CA  . VAL B 2 50  ? 333.679 333.018 480.187 1.00 133.28 ? 50  VAL H CA  1 
ATOM 1199 C C   . VAL B 2 50  ? 333.700 331.630 479.565 1.00 133.28 ? 50  VAL H C   1 
ATOM 1200 O O   . VAL B 2 50  ? 334.621 330.841 479.797 1.00 133.28 ? 50  VAL H O   1 
ATOM 1201 C CB  . VAL B 2 50  ? 334.245 334.102 479.238 1.00 133.28 ? 50  VAL H CB  1 
ATOM 1202 C CG1 . VAL B 2 50  ? 335.572 333.681 478.632 1.00 133.28 ? 50  VAL H CG1 1 
ATOM 1203 C CG2 . VAL B 2 50  ? 333.248 334.466 478.152 1.00 133.28 ? 50  VAL H CG2 1 
ATOM 1204 N N   . ILE B 2 51  ? 332.642 331.308 478.830 1.00 135.11 ? 51  ILE H N   1 
ATOM 1205 C CA  . ILE B 2 51  ? 332.616 330.154 477.945 1.00 135.11 ? 51  ILE H CA  1 
ATOM 1206 C C   . ILE B 2 51  ? 332.393 330.666 476.526 1.00 135.11 ? 51  ILE H C   1 
ATOM 1207 O O   . ILE B 2 51  ? 331.478 331.459 476.273 1.00 135.11 ? 51  ILE H O   1 
ATOM 1208 C CB  . ILE B 2 51  ? 331.566 329.118 478.384 1.00 135.11 ? 51  ILE H CB  1 
ATOM 1209 C CG1 . ILE B 2 51  ? 331.557 327.923 477.432 1.00 135.11 ? 51  ILE H CG1 1 
ATOM 1210 C CG2 . ILE B 2 51  ? 330.182 329.732 478.616 1.00 135.11 ? 51  ILE H CG2 1 
ATOM 1211 C CD1 . ILE B 2 51  ? 330.876 326.715 478.004 1.00 135.11 ? 51  ILE H CD1 1 
ATOM 1212 N N   . TRP B 2 52  ? 333.275 330.275 475.614 1.00 131.77 ? 52  TRP H N   1 
ATOM 1213 C CA  . TRP B 2 52  ? 333.175 330.773 474.256 1.00 131.77 ? 52  TRP H CA  1 
ATOM 1214 C C   . TRP B 2 52  ? 332.119 329.989 473.486 1.00 131.77 ? 52  TRP H C   1 
ATOM 1215 O O   . TRP B 2 52  ? 331.520 329.037 473.990 1.00 131.77 ? 52  TRP H O   1 
ATOM 1216 C CB  . TRP B 2 52  ? 334.525 330.693 473.552 1.00 131.77 ? 52  TRP H CB  1 
ATOM 1217 C CG  . TRP B 2 52  ? 335.637 331.379 474.281 1.00 131.77 ? 52  TRP H CG  1 
ATOM 1218 C CD1 . TRP B 2 52  ? 336.698 330.787 474.886 1.00 131.77 ? 52  TRP H CD1 1 
ATOM 1219 C CD2 . TRP B 2 52  ? 335.806 332.786 474.468 1.00 131.77 ? 52  TRP H CD2 1 
ATOM 1220 N NE1 . TRP B 2 52  ? 337.516 331.732 475.445 1.00 131.77 ? 52  TRP H NE1 1 
ATOM 1221 C CE2 . TRP B 2 52  ? 336.990 332.969 475.201 1.00 131.77 ? 52  TRP H CE2 1 
ATOM 1222 C CE3 . TRP B 2 52  ? 335.069 333.908 474.088 1.00 131.77 ? 52  TRP H CE3 1 
ATOM 1223 C CZ2 . TRP B 2 52  ? 337.455 334.224 475.562 1.00 131.77 ? 52  TRP H CZ2 1 
ATOM 1224 C CZ3 . TRP B 2 52  ? 335.532 335.153 474.449 1.00 131.77 ? 52  TRP H CZ3 1 
ATOM 1225 C CH2 . TRP B 2 52  ? 336.714 335.301 475.178 1.00 131.77 ? 52  TRP H CH2 1 
ATOM 1226 N N   . ARG B 2 53  ? 331.891 330.401 472.240 1.00 128.64 ? 53  ARG H N   1 
ATOM 1227 C CA  . ARG B 2 53  ? 330.859 329.758 471.438 1.00 128.64 ? 53  ARG H CA  1 
ATOM 1228 C C   . ARG B 2 53  ? 331.288 328.390 470.929 1.00 128.64 ? 53  ARG H C   1 
ATOM 1229 O O   . ARG B 2 53  ? 330.428 327.584 470.564 1.00 128.64 ? 53  ARG H O   1 
ATOM 1230 C CB  . ARG B 2 53  ? 330.467 330.659 470.268 1.00 128.64 ? 53  ARG H CB  1 
ATOM 1231 C CG  . ARG B 2 53  ? 331.456 330.670 469.127 1.00 128.64 ? 53  ARG H CG  1 
ATOM 1232 C CD  . ARG B 2 53  ? 331.079 331.698 468.093 1.00 128.64 ? 53  ARG H CD  1 
ATOM 1233 N NE  . ARG B 2 53  ? 331.814 332.938 468.285 1.00 128.64 ? 53  ARG H NE  1 
ATOM 1234 C CZ  . ARG B 2 53  ? 331.613 334.035 467.569 1.00 128.64 ? 53  ARG H CZ  1 
ATOM 1235 N NH1 . ARG B 2 53  ? 330.700 334.042 466.610 1.00 128.64 ? 53  ARG H NH1 1 
ATOM 1236 N NH2 . ARG B 2 53  ? 332.325 335.122 467.810 1.00 128.64 ? 53  ARG H NH2 1 
ATOM 1237 N N   . GLY B 2 54  ? 332.589 328.102 470.909 1.00 134.60 ? 54  GLY H N   1 
ATOM 1238 C CA  . GLY B 2 54  ? 333.039 326.805 470.443 1.00 134.60 ? 54  GLY H CA  1 
ATOM 1239 C C   . GLY B 2 54  ? 332.936 325.726 471.493 1.00 134.60 ? 54  GLY H C   1 
ATOM 1240 O O   . GLY B 2 54  ? 332.959 324.537 471.165 1.00 134.60 ? 54  GLY H O   1 
ATOM 1241 N N   . GLY B 2 55  ? 332.817 326.113 472.757 1.00 137.41 ? 55  GLY H N   1 
ATOM 1242 C CA  . GLY B 2 55  ? 332.771 325.155 473.839 1.00 137.41 ? 55  GLY H CA  1 
ATOM 1243 C C   . GLY B 2 55  ? 333.955 325.307 474.766 1.00 137.41 ? 55  GLY H C   1 
ATOM 1244 O O   . GLY B 2 55  ? 333.978 324.731 475.856 1.00 137.41 ? 55  GLY H O   1 
ATOM 1245 N N   . SER B 2 56  ? 334.941 326.089 474.347 1.00 135.10 ? 56  SER H N   1 
ATOM 1246 C CA  . SER B 2 56  ? 336.132 326.336 475.142 1.00 135.10 ? 56  SER H CA  1 
ATOM 1247 C C   . SER B 2 56  ? 335.848 327.401 476.190 1.00 135.10 ? 56  SER H C   1 
ATOM 1248 O O   . SER B 2 56  ? 335.091 328.344 475.953 1.00 135.10 ? 56  SER H O   1 
ATOM 1249 C CB  . SER B 2 56  ? 337.296 326.776 474.258 1.00 135.10 ? 56  SER H CB  1 
ATOM 1250 O OG  . SER B 2 56  ? 338.517 326.704 474.969 1.00 135.10 ? 56  SER H OG  1 
ATOM 1251 N N   . THR B 2 57  ? 336.448 327.231 477.362 1.00 137.15 ? 57  THR H N   1 
ATOM 1252 C CA  . THR B 2 57  ? 336.274 328.147 478.477 1.00 137.15 ? 57  THR H CA  1 
ATOM 1253 C C   . THR B 2 57  ? 337.607 328.778 478.848 1.00 137.15 ? 57  THR H C   1 
ATOM 1254 O O   . THR B 2 57  ? 338.679 328.265 478.523 1.00 137.15 ? 57  THR H O   1 
ATOM 1255 C CB  . THR B 2 57  ? 335.693 327.429 479.698 1.00 137.15 ? 57  THR H CB  1 
ATOM 1256 O OG1 . THR B 2 57  ? 336.701 326.594 480.277 1.00 137.15 ? 57  THR H OG1 1 
ATOM 1257 C CG2 . THR B 2 57  ? 334.506 326.572 479.316 1.00 137.15 ? 57  THR H CG2 1 
ATOM 1258 N N   . ASP B 2 58  ? 337.529 329.900 479.558 1.00 139.09 ? 58  ASP H N   1 
ATOM 1259 C CA  . ASP B 2 58  ? 338.726 330.580 480.032 1.00 139.09 ? 58  ASP H CA  1 
ATOM 1260 C C   . ASP B 2 58  ? 338.381 331.310 481.321 1.00 139.09 ? 58  ASP H C   1 
ATOM 1261 O O   . ASP B 2 58  ? 337.558 332.229 481.309 1.00 139.09 ? 58  ASP H O   1 
ATOM 1262 C CB  . ASP B 2 58  ? 339.253 331.552 478.975 1.00 139.09 ? 58  ASP H CB  1 
ATOM 1263 C CG  . ASP B 2 58  ? 340.712 331.888 479.171 1.00 139.09 ? 58  ASP H CG  1 
ATOM 1264 O OD1 . ASP B 2 58  ? 341.304 331.424 480.165 1.00 139.09 ? 58  ASP H OD1 1 
ATOM 1265 O OD2 . ASP B 2 58  ? 341.273 332.608 478.322 1.00 139.09 ? 58  ASP H OD2 1 
ATOM 1266 N N   . TYR B 2 59  ? 339.011 330.905 482.421 1.00 140.09 ? 59  TYR H N   1 
ATOM 1267 C CA  . TYR B 2 59  ? 338.671 331.392 483.748 1.00 140.09 ? 59  TYR H CA  1 
ATOM 1268 C C   . TYR B 2 59  ? 339.707 332.392 484.238 1.00 140.09 ? 59  TYR H C   1 
ATOM 1269 O O   . TYR B 2 59  ? 340.785 332.540 483.661 1.00 140.09 ? 59  TYR H O   1 
ATOM 1270 C CB  . TYR B 2 59  ? 338.573 330.244 484.754 1.00 140.09 ? 59  TYR H CB  1 
ATOM 1271 C CG  . TYR B 2 59  ? 337.761 329.075 484.272 1.00 140.09 ? 59  TYR H CG  1 
ATOM 1272 C CD1 . TYR B 2 59  ? 336.403 329.204 484.033 1.00 140.09 ? 59  TYR H CD1 1 
ATOM 1273 C CD2 . TYR B 2 59  ? 338.352 327.840 484.060 1.00 140.09 ? 59  TYR H CD2 1 
ATOM 1274 C CE1 . TYR B 2 59  ? 335.655 328.135 483.592 1.00 140.09 ? 59  TYR H CE1 1 
ATOM 1275 C CE2 . TYR B 2 59  ? 337.614 326.765 483.619 1.00 140.09 ? 59  TYR H CE2 1 
ATOM 1276 C CZ  . TYR B 2 59  ? 336.266 326.919 483.387 1.00 140.09 ? 59  TYR H CZ  1 
ATOM 1277 O OH  . TYR B 2 59  ? 335.524 325.851 482.946 1.00 140.09 ? 59  TYR H OH  1 
ATOM 1278 N N   . ASN B 2 60  ? 339.357 333.075 485.324 1.00 140.26 ? 60  ASN H N   1 
ATOM 1279 C CA  . ASN B 2 60  ? 340.285 333.977 485.985 1.00 140.26 ? 60  ASN H CA  1 
ATOM 1280 C C   . ASN B 2 60  ? 341.392 333.184 486.668 1.00 140.26 ? 60  ASN H C   1 
ATOM 1281 O O   . ASN B 2 60  ? 341.247 331.995 486.958 1.00 140.26 ? 60  ASN H O   1 
ATOM 1282 C CB  . ASN B 2 60  ? 339.551 334.837 487.011 1.00 140.26 ? 60  ASN H CB  1 
ATOM 1283 C CG  . ASN B 2 60  ? 340.231 336.162 487.255 1.00 140.26 ? 60  ASN H CG  1 
ATOM 1284 O OD1 . ASN B 2 60  ? 341.450 336.269 487.173 1.00 140.26 ? 60  ASN H OD1 1 
ATOM 1285 N ND2 . ASN B 2 60  ? 339.443 337.182 487.560 1.00 140.26 ? 60  ASN H ND2 1 
ATOM 1286 N N   . ALA B 2 61  ? 342.512 333.857 486.922 1.00 143.78 ? 61  ALA H N   1 
ATOM 1287 C CA  . ALA B 2 61  ? 343.639 333.186 487.557 1.00 143.78 ? 61  ALA H CA  1 
ATOM 1288 C C   . ALA B 2 61  ? 343.414 332.968 489.046 1.00 143.78 ? 61  ALA H C   1 
ATOM 1289 O O   . ALA B 2 61  ? 343.783 331.915 489.574 1.00 143.78 ? 61  ALA H O   1 
ATOM 1290 C CB  . ALA B 2 61  ? 344.921 333.986 487.335 1.00 143.78 ? 61  ALA H CB  1 
ATOM 1291 N N   . ALA B 2 62  ? 342.810 333.939 489.733 1.00 145.55 ? 62  ALA H N   1 
ATOM 1292 C CA  . ALA B 2 62  ? 342.621 333.815 491.173 1.00 145.55 ? 62  ALA H CA  1 
ATOM 1293 C C   . ALA B 2 62  ? 341.495 332.850 491.517 1.00 145.55 ? 62  ALA H C   1 
ATOM 1294 O O   . ALA B 2 62  ? 341.463 332.307 492.626 1.00 145.55 ? 62  ALA H O   1 
ATOM 1295 C CB  . ALA B 2 62  ? 342.348 335.187 491.785 1.00 145.55 ? 62  ALA H CB  1 
ATOM 1296 N N   . PHE B 2 63  ? 340.570 332.623 490.590 1.00 147.15 ? 63  PHE H N   1 
ATOM 1297 C CA  . PHE B 2 63  ? 339.454 331.720 490.829 1.00 147.15 ? 63  PHE H CA  1 
ATOM 1298 C C   . PHE B 2 63  ? 339.547 330.525 489.894 1.00 147.15 ? 63  PHE H C   1 
ATOM 1299 O O   . PHE B 2 63  ? 338.534 330.076 489.349 1.00 147.15 ? 63  PHE H O   1 
ATOM 1300 C CB  . PHE B 2 63  ? 338.117 332.438 490.628 1.00 147.15 ? 63  PHE H CB  1 
ATOM 1301 C CG  . PHE B 2 63  ? 338.007 333.749 491.352 1.00 147.15 ? 63  PHE H CG  1 
ATOM 1302 C CD1 . PHE B 2 63  ? 337.565 333.792 492.659 1.00 147.15 ? 63  PHE H CD1 1 
ATOM 1303 C CD2 . PHE B 2 63  ? 338.320 334.940 490.716 1.00 147.15 ? 63  PHE H CD2 1 
ATOM 1304 C CE1 . PHE B 2 63  ? 337.453 334.995 493.329 1.00 147.15 ? 63  PHE H CE1 1 
ATOM 1305 C CE2 . PHE B 2 63  ? 338.212 336.145 491.381 1.00 147.15 ? 63  PHE H CE2 1 
ATOM 1306 C CZ  . PHE B 2 63  ? 337.778 336.171 492.688 1.00 147.15 ? 63  PHE H CZ  1 
ATOM 1307 N N   . MET B 2 64  ? 340.757 330.003 489.701 1.00 150.86 ? 64  MET H N   1 
ATOM 1308 C CA  . MET B 2 64  ? 340.973 328.984 488.681 1.00 150.86 ? 64  MET H CA  1 
ATOM 1309 C C   . MET B 2 64  ? 340.495 327.613 489.138 1.00 150.86 ? 64  MET H C   1 
ATOM 1310 O O   . MET B 2 64  ? 339.744 326.940 488.424 1.00 150.86 ? 64  MET H O   1 
ATOM 1311 C CB  . MET B 2 64  ? 342.452 328.932 488.303 1.00 150.86 ? 64  MET H CB  1 
ATOM 1312 C CG  . MET B 2 64  ? 342.794 327.852 487.294 1.00 150.86 ? 64  MET H CG  1 
ATOM 1313 S SD  . MET B 2 64  ? 342.719 328.442 485.592 1.00 150.86 ? 64  MET H SD  1 
ATOM 1314 C CE  . MET B 2 64  ? 343.816 329.853 485.672 1.00 150.86 ? 64  MET H CE  1 
ATOM 1315 N N   . SER B 2 65  ? 340.916 327.183 490.327 1.00 153.79 ? 65  SER H N   1 
ATOM 1316 C CA  . SER B 2 65  ? 340.623 325.825 490.771 1.00 153.79 ? 65  SER H CA  1 
ATOM 1317 C C   . SER B 2 65  ? 339.199 325.689 491.293 1.00 153.79 ? 65  SER H C   1 
ATOM 1318 O O   . SER B 2 65  ? 338.682 324.573 491.406 1.00 153.79 ? 65  SER H O   1 
ATOM 1319 C CB  . SER B 2 65  ? 341.617 325.403 491.849 1.00 153.79 ? 65  SER H CB  1 
ATOM 1320 O OG  . SER B 2 65  ? 341.201 325.867 493.120 1.00 153.79 ? 65  SER H OG  1 
ATOM 1321 N N   . ARG B 2 66  ? 338.553 326.804 491.622 1.00 152.87 ? 66  ARG H N   1 
ATOM 1322 C CA  . ARG B 2 66  ? 337.238 326.744 492.243 1.00 152.87 ? 66  ARG H CA  1 
ATOM 1323 C C   . ARG B 2 66  ? 336.094 326.826 491.244 1.00 152.87 ? 66  ARG H C   1 
ATOM 1324 O O   . ARG B 2 66  ? 334.959 326.499 491.602 1.00 152.87 ? 66  ARG H O   1 
ATOM 1325 C CB  . ARG B 2 66  ? 337.098 327.868 493.267 1.00 152.87 ? 66  ARG H CB  1 
ATOM 1326 C CG  . ARG B 2 66  ? 338.018 327.720 494.453 1.00 152.87 ? 66  ARG H CG  1 
ATOM 1327 C CD  . ARG B 2 66  ? 337.743 328.781 495.493 1.00 152.87 ? 66  ARG H CD  1 
ATOM 1328 N NE  . ARG B 2 66  ? 338.269 330.089 495.126 1.00 152.87 ? 66  ARG H NE  1 
ATOM 1329 C CZ  . ARG B 2 66  ? 338.010 331.202 495.802 1.00 152.87 ? 66  ARG H CZ  1 
ATOM 1330 N NH1 . ARG B 2 66  ? 337.225 331.162 496.868 1.00 152.87 ? 66  ARG H NH1 1 
ATOM 1331 N NH2 . ARG B 2 66  ? 338.534 332.354 495.414 1.00 152.87 ? 66  ARG H NH2 1 
ATOM 1332 N N   . LEU B 2 67  ? 336.357 327.244 490.011 1.00 147.91 ? 67  LEU H N   1 
ATOM 1333 C CA  . LEU B 2 67  ? 335.306 327.541 489.050 1.00 147.91 ? 67  LEU H CA  1 
ATOM 1334 C C   . LEU B 2 67  ? 335.185 326.439 488.009 1.00 147.91 ? 67  LEU H C   1 
ATOM 1335 O O   . LEU B 2 67  ? 336.158 325.739 487.714 1.00 147.91 ? 67  LEU H O   1 
ATOM 1336 C CB  . LEU B 2 67  ? 335.577 328.868 488.349 1.00 147.91 ? 67  LEU H CB  1 
ATOM 1337 C CG  . LEU B 2 67  ? 334.914 330.081 488.983 1.00 147.91 ? 67  LEU H CG  1 
ATOM 1338 C CD1 . LEU B 2 67  ? 335.415 331.348 488.333 1.00 147.91 ? 67  LEU H CD1 1 
ATOM 1339 C CD2 . LEU B 2 67  ? 333.421 329.962 488.843 1.00 147.91 ? 67  LEU H CD2 1 
ATOM 1340 N N   . SER B 2 68  ? 333.985 326.302 487.450 1.00 144.27 ? 68  SER H N   1 
ATOM 1341 C CA  . SER B 2 68  ? 333.729 325.392 486.341 1.00 144.27 ? 68  SER H CA  1 
ATOM 1342 C C   . SER B 2 68  ? 332.457 325.837 485.641 1.00 144.27 ? 68  SER H C   1 
ATOM 1343 O O   . SER B 2 68  ? 331.373 325.752 486.222 1.00 144.27 ? 68  SER H O   1 
ATOM 1344 C CB  . SER B 2 68  ? 333.579 323.947 486.820 1.00 144.27 ? 68  SER H CB  1 
ATOM 1345 O OG  . SER B 2 68  ? 332.407 323.799 487.600 1.00 144.27 ? 68  SER H OG  1 
ATOM 1346 N N   . ILE B 2 69  ? 332.587 326.298 484.400 1.00 140.12 ? 69  ILE H N   1 
ATOM 1347 C CA  . ILE B 2 69  ? 331.461 326.785 483.614 1.00 140.12 ? 69  ILE H CA  1 
ATOM 1348 C C   . ILE B 2 69  ? 331.266 325.860 482.426 1.00 140.12 ? 69  ILE H C   1 
ATOM 1349 O O   . ILE B 2 69  ? 332.214 325.598 481.678 1.00 140.12 ? 69  ILE H O   1 
ATOM 1350 C CB  . ILE B 2 69  ? 331.684 328.230 483.138 1.00 140.12 ? 69  ILE H CB  1 
ATOM 1351 C CG1 . ILE B 2 69  ? 332.221 329.091 484.274 1.00 140.12 ? 69  ILE H CG1 1 
ATOM 1352 C CG2 . ILE B 2 69  ? 330.396 328.811 482.607 1.00 140.12 ? 69  ILE H CG2 1 
ATOM 1353 C CD1 . ILE B 2 69  ? 332.691 330.445 483.829 1.00 140.12 ? 69  ILE H CD1 1 
ATOM 1354 N N   . THR B 2 70  ? 330.044 325.369 482.251 1.00 143.32 ? 70  THR H N   1 
ATOM 1355 C CA  . THR B 2 70  ? 329.682 324.513 481.130 1.00 143.32 ? 70  THR H CA  1 
ATOM 1356 C C   . THR B 2 70  ? 328.333 324.959 480.583 1.00 143.32 ? 70  THR H C   1 
ATOM 1357 O O   . THR B 2 70  ? 327.587 325.691 481.236 1.00 143.32 ? 70  THR H O   1 
ATOM 1358 C CB  . THR B 2 70  ? 329.630 323.037 481.542 1.00 143.32 ? 70  THR H CB  1 
ATOM 1359 O OG1 . THR B 2 70  ? 328.974 322.917 482.810 1.00 143.32 ? 70  THR H OG1 1 
ATOM 1360 C CG2 . THR B 2 70  ? 331.029 322.443 481.626 1.00 143.32 ? 70  THR H CG2 1 
ATOM 1361 N N   . LYS B 2 71  ? 328.005 324.498 479.379 1.00 141.75 ? 71  LYS H N   1 
ATOM 1362 C CA  . LYS B 2 71  ? 326.759 324.907 478.750 1.00 141.75 ? 71  LYS H CA  1 
ATOM 1363 C C   . LYS B 2 71  ? 326.244 323.784 477.870 1.00 141.75 ? 71  LYS H C   1 
ATOM 1364 O O   . LYS B 2 71  ? 326.923 322.779 477.649 1.00 141.75 ? 71  LYS H O   1 
ATOM 1365 C CB  . LYS B 2 71  ? 326.934 326.190 477.933 1.00 141.75 ? 71  LYS H CB  1 
ATOM 1366 C CG  . LYS B 2 71  ? 327.556 326.002 476.555 1.00 141.75 ? 71  LYS H CG  1 
ATOM 1367 C CD  . LYS B 2 71  ? 327.655 327.338 475.838 1.00 141.75 ? 71  LYS H CD  1 
ATOM 1368 C CE  . LYS B 2 71  ? 328.699 327.321 474.741 1.00 141.75 ? 71  LYS H CE  1 
ATOM 1369 N NZ  . LYS B 2 71  ? 328.283 326.489 473.591 1.00 141.75 ? 71  LYS H NZ  1 
ATOM 1370 N N   . ASP B 2 72  ? 325.023 323.973 477.375 1.00 147.89 ? 72  ASP H N   1 
ATOM 1371 C CA  . ASP B 2 72  ? 324.378 323.039 476.463 1.00 147.89 ? 72  ASP H CA  1 
ATOM 1372 C C   . ASP B 2 72  ? 323.725 323.829 475.342 1.00 147.89 ? 72  ASP H C   1 
ATOM 1373 O O   . ASP B 2 72  ? 322.945 324.749 475.603 1.00 147.89 ? 72  ASP H O   1 
ATOM 1374 C CB  . ASP B 2 72  ? 323.338 322.188 477.189 1.00 147.89 ? 72  ASP H CB  1 
ATOM 1375 C CG  . ASP B 2 72  ? 322.456 321.422 476.234 1.00 147.89 ? 72  ASP H CG  1 
ATOM 1376 O OD1 . ASP B 2 72  ? 322.873 320.340 475.775 1.00 147.89 ? 72  ASP H OD1 1 
ATOM 1377 O OD2 . ASP B 2 72  ? 321.349 321.910 475.932 1.00 147.89 ? 72  ASP H OD2 1 
ATOM 1378 N N   . ASN B 2 73  ? 324.036 323.465 474.097 1.00 148.10 ? 73  ASN H N   1 
ATOM 1379 C CA  . ASN B 2 73  ? 323.483 324.187 472.958 1.00 148.10 ? 73  ASN H CA  1 
ATOM 1380 C C   . ASN B 2 73  ? 322.012 323.864 472.736 1.00 148.10 ? 73  ASN H C   1 
ATOM 1381 O O   . ASN B 2 73  ? 321.276 324.691 472.188 1.00 148.10 ? 73  ASN H O   1 
ATOM 1382 C CB  . ASN B 2 73  ? 324.279 323.863 471.697 1.00 148.10 ? 73  ASN H CB  1 
ATOM 1383 C CG  . ASN B 2 73  ? 325.718 324.307 471.789 1.00 148.10 ? 73  ASN H CG  1 
ATOM 1384 O OD1 . ASN B 2 73  ? 326.634 323.487 471.802 1.00 148.10 ? 73  ASN H OD1 1 
ATOM 1385 N ND2 . ASN B 2 73  ? 325.928 325.613 471.848 1.00 148.10 ? 73  ASN H ND2 1 
ATOM 1386 N N   . SER B 2 74  ? 321.566 322.676 473.150 1.00 149.22 ? 74  SER H N   1 
ATOM 1387 C CA  . SER B 2 74  ? 320.215 322.240 472.813 1.00 149.22 ? 74  SER H CA  1 
ATOM 1388 C C   . SER B 2 74  ? 319.170 322.906 473.698 1.00 149.22 ? 74  SER H C   1 
ATOM 1389 O O   . SER B 2 74  ? 318.249 323.556 473.193 1.00 149.22 ? 74  SER H O   1 
ATOM 1390 C CB  . SER B 2 74  ? 320.113 320.720 472.919 1.00 149.22 ? 74  SER H CB  1 
ATOM 1391 O OG  . SER B 2 74  ? 318.760 320.305 472.891 1.00 149.22 ? 74  SER H OG  1 
ATOM 1392 N N   . LYS B 2 75  ? 319.290 322.760 475.018 1.00 149.74 ? 75  LYS H N   1 
ATOM 1393 C CA  . LYS B 2 75  ? 318.320 323.367 475.921 1.00 149.74 ? 75  LYS H CA  1 
ATOM 1394 C C   . LYS B 2 75  ? 318.610 324.833 476.215 1.00 149.74 ? 75  LYS H C   1 
ATOM 1395 O O   . LYS B 2 75  ? 317.839 325.445 476.964 1.00 149.74 ? 75  LYS H O   1 
ATOM 1396 C CB  . LYS B 2 75  ? 318.243 322.590 477.238 1.00 149.74 ? 75  LYS H CB  1 
ATOM 1397 C CG  . LYS B 2 75  ? 317.613 321.212 477.116 1.00 149.74 ? 75  LYS H CG  1 
ATOM 1398 C CD  . LYS B 2 75  ? 318.184 320.228 478.124 1.00 149.74 ? 75  LYS H CD  1 
ATOM 1399 C CE  . LYS B 2 75  ? 319.625 319.881 477.819 1.00 149.74 ? 75  LYS H CE  1 
ATOM 1400 N NZ  . LYS B 2 75  ? 319.786 319.349 476.439 1.00 149.74 ? 75  LYS H NZ  1 
ATOM 1401 N N   . SER B 2 76  ? 319.698 325.382 475.657 1.00 147.03 ? 76  SER H N   1 
ATOM 1402 C CA  . SER B 2 76  ? 320.047 326.807 475.721 1.00 147.03 ? 76  SER H CA  1 
ATOM 1403 C C   . SER B 2 76  ? 320.233 327.284 477.161 1.00 147.03 ? 76  SER H C   1 
ATOM 1404 O O   . SER B 2 76  ? 319.583 328.223 477.620 1.00 147.03 ? 76  SER H O   1 
ATOM 1405 C CB  . SER B 2 76  ? 319.016 327.665 474.982 1.00 147.03 ? 76  SER H CB  1 
ATOM 1406 O OG  . SER B 2 76  ? 318.684 327.088 473.734 1.00 147.03 ? 76  SER H OG  1 
ATOM 1407 N N   . GLN B 2 77  ? 321.134 326.618 477.877 1.00 146.44 ? 77  GLN H N   1 
ATOM 1408 C CA  . GLN B 2 77  ? 321.397 326.918 479.275 1.00 146.44 ? 77  GLN H CA  1 
ATOM 1409 C C   . GLN B 2 77  ? 322.891 326.852 479.535 1.00 146.44 ? 77  GLN H C   1 
ATOM 1410 O O   . GLN B 2 77  ? 323.608 326.092 478.880 1.00 146.44 ? 77  GLN H O   1 
ATOM 1411 C CB  . GLN B 2 77  ? 320.673 325.939 480.201 1.00 146.44 ? 77  GLN H CB  1 
ATOM 1412 C CG  . GLN B 2 77  ? 319.181 326.174 480.324 1.00 146.44 ? 77  GLN H CG  1 
ATOM 1413 C CD  . GLN B 2 77  ? 318.479 325.034 481.019 1.00 146.44 ? 77  GLN H CD  1 
ATOM 1414 O OE1 . GLN B 2 77  ? 319.115 324.077 481.459 1.00 146.44 ? 77  GLN H OE1 1 
ATOM 1415 N NE2 . GLN B 2 77  ? 317.161 325.127 481.124 1.00 146.44 ? 77  GLN H NE2 1 
ATOM 1416 N N   . VAL B 2 78  ? 323.353 327.644 480.495 1.00 142.13 ? 78  VAL H N   1 
ATOM 1417 C CA  . VAL B 2 78  ? 324.742 327.633 480.928 1.00 142.13 ? 78  VAL H CA  1 
ATOM 1418 C C   . VAL B 2 78  ? 324.785 327.468 482.444 1.00 142.13 ? 78  VAL H C   1 
ATOM 1419 O O   . VAL B 2 78  ? 324.075 328.160 483.181 1.00 142.13 ? 78  VAL H O   1 
ATOM 1420 C CB  . VAL B 2 78  ? 325.498 328.894 480.442 1.00 142.13 ? 78  VAL H CB  1 
ATOM 1421 C CG1 . VAL B 2 78  ? 324.775 330.178 480.804 1.00 142.13 ? 78  VAL H CG1 1 
ATOM 1422 C CG2 . VAL B 2 78  ? 326.905 328.929 480.999 1.00 142.13 ? 78  VAL H CG2 1 
ATOM 1423 N N   . PHE B 2 79  ? 325.568 326.496 482.903 1.00 142.14 ? 79  PHE H N   1 
ATOM 1424 C CA  . PHE B 2 79  ? 325.705 326.197 484.322 1.00 142.14 ? 79  PHE H CA  1 
ATOM 1425 C C   . PHE B 2 79  ? 327.108 326.578 484.758 1.00 142.14 ? 79  PHE H C   1 
ATOM 1426 O O   . PHE B 2 79  ? 328.078 326.251 484.069 1.00 142.14 ? 79  PHE H O   1 
ATOM 1427 C CB  . PHE B 2 79  ? 325.463 324.712 484.608 1.00 142.14 ? 79  PHE H CB  1 
ATOM 1428 C CG  . PHE B 2 79  ? 324.288 324.131 483.884 1.00 142.14 ? 79  PHE H CG  1 
ATOM 1429 C CD1 . PHE B 2 79  ? 323.000 324.530 484.191 1.00 142.14 ? 79  PHE H CD1 1 
ATOM 1430 C CD2 . PHE B 2 79  ? 324.473 323.169 482.906 1.00 142.14 ? 79  PHE H CD2 1 
ATOM 1431 C CE1 . PHE B 2 79  ? 321.916 323.988 483.528 1.00 142.14 ? 79  PHE H CE1 1 
ATOM 1432 C CE2 . PHE B 2 79  ? 323.395 322.623 482.238 1.00 142.14 ? 79  PHE H CE2 1 
ATOM 1433 C CZ  . PHE B 2 79  ? 322.115 323.033 482.550 1.00 142.14 ? 79  PHE H CZ  1 
ATOM 1434 N N   . PHE B 2 80  ? 327.225 327.254 485.897 1.00 144.33 ? 80  PHE H N   1 
ATOM 1435 C CA  . PHE B 2 80  ? 328.534 327.500 486.474 1.00 144.33 ? 80  PHE H CA  1 
ATOM 1436 C C   . PHE B 2 80  ? 328.489 327.206 487.965 1.00 144.33 ? 80  PHE H C   1 
ATOM 1437 O O   . PHE B 2 80  ? 327.451 327.338 488.614 1.00 144.33 ? 80  PHE H O   1 
ATOM 1438 C CB  . PHE B 2 80  ? 329.019 328.931 486.195 1.00 144.33 ? 80  PHE H CB  1 
ATOM 1439 C CG  . PHE B 2 80  ? 328.821 329.891 487.328 1.00 144.33 ? 80  PHE H CG  1 
ATOM 1440 C CD1 . PHE B 2 80  ? 327.579 330.440 487.588 1.00 144.33 ? 80  PHE H CD1 1 
ATOM 1441 C CD2 . PHE B 2 80  ? 329.902 330.291 488.097 1.00 144.33 ? 80  PHE H CD2 1 
ATOM 1442 C CE1 . PHE B 2 80  ? 327.416 331.337 488.623 1.00 144.33 ? 80  PHE H CE1 1 
ATOM 1443 C CE2 . PHE B 2 80  ? 329.746 331.184 489.127 1.00 144.33 ? 80  PHE H CE2 1 
ATOM 1444 C CZ  . PHE B 2 80  ? 328.503 331.709 489.392 1.00 144.33 ? 80  PHE H CZ  1 
ATOM 1445 N N   . LYS B 2 81  ? 329.641 326.815 488.503 1.00 150.19 ? 81  LYS H N   1 
ATOM 1446 C CA  . LYS B 2 81  ? 329.726 326.322 489.868 1.00 150.19 ? 81  LYS H CA  1 
ATOM 1447 C C   . LYS B 2 81  ? 331.000 326.828 490.521 1.00 150.19 ? 81  LYS H C   1 
ATOM 1448 O O   . LYS B 2 81  ? 332.090 326.668 489.966 1.00 150.19 ? 81  LYS H O   1 
ATOM 1449 C CB  . LYS B 2 81  ? 329.691 324.791 489.896 1.00 150.19 ? 81  LYS H CB  1 
ATOM 1450 C CG  . LYS B 2 81  ? 330.125 324.181 491.214 1.00 150.19 ? 81  LYS H CG  1 
ATOM 1451 C CD  . LYS B 2 81  ? 330.285 322.677 491.102 1.00 150.19 ? 81  LYS H CD  1 
ATOM 1452 C CE  . LYS B 2 81  ? 328.968 322.012 490.746 1.00 150.19 ? 81  LYS H CE  1 
ATOM 1453 N NZ  . LYS B 2 81  ? 327.905 322.335 491.735 1.00 150.19 ? 81  LYS H NZ  1 
ATOM 1454 N N   . MET B 2 82  ? 330.858 327.434 491.695 1.00 156.45 ? 82  MET H N   1 
ATOM 1455 C CA  . MET B 2 82  ? 331.983 327.880 492.501 1.00 156.45 ? 82  MET H CA  1 
ATOM 1456 C C   . MET B 2 82  ? 331.952 327.130 493.824 1.00 156.45 ? 82  MET H C   1 
ATOM 1457 O O   . MET B 2 82  ? 330.876 326.868 494.368 1.00 156.45 ? 82  MET H O   1 
ATOM 1458 C CB  . MET B 2 82  ? 331.929 329.395 492.734 1.00 156.45 ? 82  MET H CB  1 
ATOM 1459 C CG  . MET B 2 82  ? 333.162 329.978 493.394 1.00 156.45 ? 82  MET H CG  1 
ATOM 1460 S SD  . MET B 2 82  ? 333.057 331.761 493.592 1.00 156.45 ? 82  MET H SD  1 
ATOM 1461 C CE  . MET B 2 82  ? 333.258 332.284 491.896 1.00 156.45 ? 82  MET H CE  1 
ATOM 1462 N N   . ASN B 2 83  ? 333.127 326.775 494.334 1.00 159.86 ? 83  ASN H N   1 
ATOM 1463 C CA  . ASN B 2 83  ? 333.230 325.954 495.528 1.00 159.86 ? 83  ASN H CA  1 
ATOM 1464 C C   . ASN B 2 83  ? 334.015 326.665 496.622 1.00 159.86 ? 83  ASN H C   1 
ATOM 1465 O O   . ASN B 2 83  ? 334.772 327.607 496.372 1.00 159.86 ? 83  ASN H O   1 
ATOM 1466 C CB  . ASN B 2 83  ? 333.887 324.608 495.215 1.00 159.86 ? 83  ASN H CB  1 
ATOM 1467 C CG  . ASN B 2 83  ? 333.222 323.896 494.062 1.00 159.86 ? 83  ASN H CG  1 
ATOM 1468 O OD1 . ASN B 2 83  ? 332.217 323.211 494.239 1.00 159.86 ? 83  ASN H OD1 1 
ATOM 1469 N ND2 . ASN B 2 83  ? 333.777 324.057 492.869 1.00 159.86 ? 83  ASN H ND2 1 
ATOM 1470 N N   . SER B 2 84  ? 333.775 326.206 497.855 1.00 165.09 ? 84  SER H N   1 
ATOM 1471 C CA  . SER B 2 84  ? 334.462 326.484 499.122 1.00 165.09 ? 84  SER H CA  1 
ATOM 1472 C C   . SER B 2 84  ? 334.220 327.882 499.687 1.00 165.09 ? 84  SER H C   1 
ATOM 1473 O O   . SER B 2 84  ? 334.616 328.132 500.830 1.00 165.09 ? 84  SER H O   1 
ATOM 1474 C CB  . SER B 2 84  ? 335.981 326.243 499.039 1.00 165.09 ? 84  SER H CB  1 
ATOM 1475 O OG  . SER B 2 84  ? 336.634 326.988 498.029 1.00 165.09 ? 84  SER H OG  1 
ATOM 1476 N N   . LEU B 2 85  ? 333.635 328.790 498.890 1.00 166.35 ? 85  LEU H N   1 
ATOM 1477 C CA  . LEU B 2 85  ? 332.779 329.910 499.304 1.00 166.35 ? 85  LEU H CA  1 
ATOM 1478 C C   . LEU B 2 85  ? 333.165 330.666 500.572 1.00 166.35 ? 85  LEU H C   1 
ATOM 1479 O O   . LEU B 2 85  ? 332.476 330.554 501.589 1.00 166.35 ? 85  LEU H O   1 
ATOM 1480 C CB  . LEU B 2 85  ? 331.332 329.432 499.433 1.00 166.35 ? 85  LEU H CB  1 
ATOM 1481 C CG  . LEU B 2 85  ? 330.433 329.699 498.219 1.00 166.35 ? 85  LEU H CG  1 
ATOM 1482 C CD1 . LEU B 2 85  ? 330.272 331.196 498.036 1.00 166.35 ? 85  LEU H CD1 1 
ATOM 1483 C CD2 . LEU B 2 85  ? 330.937 329.080 496.926 1.00 166.35 ? 85  LEU H CD2 1 
ATOM 1484 N N   . GLN B 2 86  ? 334.283 331.384 500.558 1.00 169.05 ? 86  GLN H N   1 
ATOM 1485 C CA  . GLN B 2 86  ? 334.715 332.094 501.752 1.00 169.05 ? 86  GLN H CA  1 
ATOM 1486 C C   . GLN B 2 86  ? 333.883 333.359 501.979 1.00 169.05 ? 86  GLN H C   1 
ATOM 1487 O O   . GLN B 2 86  ? 332.873 333.611 501.315 1.00 169.05 ? 86  GLN H O   1 
ATOM 1488 C CB  . GLN B 2 86  ? 336.202 332.423 501.662 1.00 169.05 ? 86  GLN H CB  1 
ATOM 1489 C CG  . GLN B 2 86  ? 337.102 331.350 502.255 1.00 169.05 ? 86  GLN H CG  1 
ATOM 1490 C CD  . GLN B 2 86  ? 336.505 330.698 503.491 1.00 169.05 ? 86  GLN H CD  1 
ATOM 1491 O OE1 . GLN B 2 86  ? 336.400 331.322 504.547 1.00 169.05 ? 86  GLN H OE1 1 
ATOM 1492 N NE2 . GLN B 2 86  ? 336.115 329.435 503.364 1.00 169.05 ? 86  GLN H NE2 1 
ATOM 1493 N N   . ALA B 2 87  ? 334.318 334.171 502.944 1.00 168.17 ? 87  ALA H N   1 
ATOM 1494 C CA  . ALA B 2 87  ? 333.510 335.285 503.425 1.00 168.17 ? 87  ALA H CA  1 
ATOM 1495 C C   . ALA B 2 87  ? 333.469 336.468 502.466 1.00 168.17 ? 87  ALA H C   1 
ATOM 1496 O O   . ALA B 2 87  ? 332.572 337.308 502.586 1.00 168.17 ? 87  ALA H O   1 
ATOM 1497 C CB  . ALA B 2 87  ? 334.025 335.756 504.787 1.00 168.17 ? 87  ALA H CB  1 
ATOM 1498 N N   . ASP B 2 88  ? 334.408 336.560 501.528 1.00 168.84 ? 88  ASP H N   1 
ATOM 1499 C CA  . ASP B 2 88  ? 334.451 337.687 500.604 1.00 168.84 ? 88  ASP H CA  1 
ATOM 1500 C C   . ASP B 2 88  ? 333.458 337.572 499.455 1.00 168.84 ? 88  ASP H C   1 
ATOM 1501 O O   . ASP B 2 88  ? 333.334 338.518 498.671 1.00 168.84 ? 88  ASP H O   1 
ATOM 1502 C CB  . ASP B 2 88  ? 335.873 337.866 500.056 1.00 168.84 ? 88  ASP H CB  1 
ATOM 1503 C CG  . ASP B 2 88  ? 336.460 336.580 499.468 1.00 168.84 ? 88  ASP H CG  1 
ATOM 1504 O OD1 . ASP B 2 88  ? 335.725 335.595 499.242 1.00 168.84 ? 88  ASP H OD1 1 
ATOM 1505 O OD2 . ASP B 2 88  ? 337.685 336.562 499.222 1.00 168.84 ? 88  ASP H OD2 1 
ATOM 1506 N N   . ASP B 2 89  ? 332.754 336.451 499.333 1.00 164.82 ? 89  ASP H N   1 
ATOM 1507 C CA  . ASP B 2 89  ? 331.882 336.221 498.191 1.00 164.82 ? 89  ASP H CA  1 
ATOM 1508 C C   . ASP B 2 89  ? 330.482 336.791 498.371 1.00 164.82 ? 89  ASP H C   1 
ATOM 1509 O O   . ASP B 2 89  ? 329.587 336.428 497.602 1.00 164.82 ? 89  ASP H O   1 
ATOM 1510 C CB  . ASP B 2 89  ? 331.800 334.723 497.899 1.00 164.82 ? 89  ASP H CB  1 
ATOM 1511 C CG  . ASP B 2 89  ? 333.149 334.124 497.564 1.00 164.82 ? 89  ASP H CG  1 
ATOM 1512 O OD1 . ASP B 2 89  ? 333.998 334.852 497.011 1.00 164.82 ? 89  ASP H OD1 1 
ATOM 1513 O OD2 . ASP B 2 89  ? 333.365 332.930 497.853 1.00 164.82 ? 89  ASP H OD2 1 
ATOM 1514 N N   . THR B 2 90  ? 330.265 337.658 499.356 1.00 164.44 ? 90  THR H N   1 
ATOM 1515 C CA  . THR B 2 90  ? 328.989 338.356 499.494 1.00 164.44 ? 90  THR H CA  1 
ATOM 1516 C C   . THR B 2 90  ? 328.888 339.379 498.377 1.00 164.44 ? 90  THR H C   1 
ATOM 1517 O O   . THR B 2 90  ? 329.436 340.478 498.477 1.00 164.44 ? 90  THR H O   1 
ATOM 1518 C CB  . THR B 2 90  ? 328.884 339.036 500.852 1.00 164.44 ? 90  THR H CB  1 
ATOM 1519 O OG1 . THR B 2 90  ? 329.957 339.974 500.998 1.00 164.44 ? 90  THR H OG1 1 
ATOM 1520 C CG2 . THR B 2 90  ? 328.951 338.019 501.966 1.00 164.44 ? 90  THR H CG2 1 
ATOM 1521 N N   . ALA B 2 91  ? 328.178 339.025 497.312 1.00 157.74 ? 91  ALA H N   1 
ATOM 1522 C CA  . ALA B 2 91  ? 328.095 339.873 496.133 1.00 157.74 ? 91  ALA H CA  1 
ATOM 1523 C C   . ALA B 2 91  ? 326.850 339.490 495.347 1.00 157.74 ? 91  ALA H C   1 
ATOM 1524 O O   . ALA B 2 91  ? 326.049 338.658 495.778 1.00 157.74 ? 91  ALA H O   1 
ATOM 1525 C CB  . ALA B 2 91  ? 329.354 339.741 495.280 1.00 157.74 ? 91  ALA H CB  1 
ATOM 1526 N N   . ILE B 2 92  ? 326.692 340.113 494.184 1.00 149.12 ? 92  ILE H N   1 
ATOM 1527 C CA  . ILE B 2 92  ? 325.630 339.783 493.243 1.00 149.12 ? 92  ILE H CA  1 
ATOM 1528 C C   . ILE B 2 92  ? 326.286 339.299 491.955 1.00 149.12 ? 92  ILE H C   1 
ATOM 1529 O O   . ILE B 2 92  ? 327.328 339.822 491.543 1.00 149.12 ? 92  ILE H O   1 
ATOM 1530 C CB  . ILE B 2 92  ? 324.682 340.979 493.022 1.00 149.12 ? 92  ILE H CB  1 
ATOM 1531 C CG1 . ILE B 2 92  ? 323.496 340.599 492.132 1.00 149.12 ? 92  ILE H CG1 1 
ATOM 1532 C CG2 . ILE B 2 92  ? 325.413 342.211 492.519 1.00 149.12 ? 92  ILE H CG2 1 
ATOM 1533 C CD1 . ILE B 2 92  ? 322.391 341.624 492.132 1.00 149.12 ? 92  ILE H CD1 1 
ATOM 1534 N N   . TYR B 2 93  ? 325.722 338.253 491.362 1.00 146.34 ? 93  TYR H N   1 
ATOM 1535 C CA  . TYR B 2 93  ? 326.339 337.575 490.233 1.00 146.34 ? 93  TYR H CA  1 
ATOM 1536 C C   . TYR B 2 93  ? 325.502 337.767 488.978 1.00 146.34 ? 93  TYR H C   1 
ATOM 1537 O O   . TYR B 2 93  ? 324.305 337.471 488.967 1.00 146.34 ? 93  TYR H O   1 
ATOM 1538 C CB  . TYR B 2 93  ? 326.509 336.085 490.527 1.00 146.34 ? 93  TYR H CB  1 
ATOM 1539 C CG  . TYR B 2 93  ? 327.596 335.787 491.531 1.00 146.34 ? 93  TYR H CG  1 
ATOM 1540 C CD1 . TYR B 2 93  ? 327.369 335.921 492.892 1.00 146.34 ? 93  TYR H CD1 1 
ATOM 1541 C CD2 . TYR B 2 93  ? 328.851 335.374 491.117 1.00 146.34 ? 93  TYR H CD2 1 
ATOM 1542 C CE1 . TYR B 2 93  ? 328.359 335.655 493.809 1.00 146.34 ? 93  TYR H CE1 1 
ATOM 1543 C CE2 . TYR B 2 93  ? 329.846 335.103 492.030 1.00 146.34 ? 93  TYR H CE2 1 
ATOM 1544 C CZ  . TYR B 2 93  ? 329.594 335.245 493.372 1.00 146.34 ? 93  TYR H CZ  1 
ATOM 1545 O OH  . TYR B 2 93  ? 330.587 334.976 494.281 1.00 146.34 ? 93  TYR H OH  1 
ATOM 1546 N N   . TYR B 2 94  ? 326.141 338.257 487.920 1.00 144.44 ? 94  TYR H N   1 
ATOM 1547 C CA  . TYR B 2 94  ? 325.481 338.505 486.650 1.00 144.44 ? 94  TYR H CA  1 
ATOM 1548 C C   . TYR B 2 94  ? 325.938 337.495 485.611 1.00 144.44 ? 94  TYR H C   1 
ATOM 1549 O O   . TYR B 2 94  ? 327.069 337.007 485.651 1.00 144.44 ? 94  TYR H O   1 
ATOM 1550 C CB  . TYR B 2 94  ? 325.784 339.905 486.113 1.00 144.44 ? 94  TYR H CB  1 
ATOM 1551 C CG  . TYR B 2 94  ? 325.368 341.047 487.001 1.00 144.44 ? 94  TYR H CG  1 
ATOM 1552 C CD1 . TYR B 2 94  ? 324.031 341.376 487.162 1.00 144.44 ? 94  TYR H CD1 1 
ATOM 1553 C CD2 . TYR B 2 94  ? 326.317 341.812 487.657 1.00 144.44 ? 94  TYR H CD2 1 
ATOM 1554 C CE1 . TYR B 2 94  ? 323.652 342.429 487.965 1.00 144.44 ? 94  TYR H CE1 1 
ATOM 1555 C CE2 . TYR B 2 94  ? 325.949 342.864 488.460 1.00 144.44 ? 94  TYR H CE2 1 
ATOM 1556 C CZ  . TYR B 2 94  ? 324.617 343.169 488.613 1.00 144.44 ? 94  TYR H CZ  1 
ATOM 1557 O OH  . TYR B 2 94  ? 324.254 344.221 489.418 1.00 144.44 ? 94  TYR H OH  1 
ATOM 1558 N N   . CYS B 2 95  ? 325.048 337.193 484.674 1.00 144.64 ? 95  CYS H N   1 
ATOM 1559 C CA  . CYS B 2 95  ? 325.418 336.555 483.422 1.00 144.64 ? 95  CYS H CA  1 
ATOM 1560 C C   . CYS B 2 95  ? 325.112 337.541 482.310 1.00 144.64 ? 95  CYS H C   1 
ATOM 1561 O O   . CYS B 2 95  ? 324.060 338.186 482.326 1.00 144.64 ? 95  CYS H O   1 
ATOM 1562 C CB  . CYS B 2 95  ? 324.668 335.237 483.195 1.00 144.64 ? 95  CYS H CB  1 
ATOM 1563 S SG  . CYS B 2 95  ? 322.886 335.286 483.479 1.00 144.64 ? 95  CYS H SG  1 
ATOM 1564 N N   . ALA B 2 96  ? 326.038 337.685 481.369 1.00 134.19 ? 96  ALA H N   1 
ATOM 1565 C CA  . ALA B 2 96  ? 325.849 338.594 480.252 1.00 134.19 ? 96  ALA H CA  1 
ATOM 1566 C C   . ALA B 2 96  ? 326.523 338.021 479.020 1.00 134.19 ? 96  ALA H C   1 
ATOM 1567 O O   . ALA B 2 96  ? 327.612 337.448 479.103 1.00 134.19 ? 96  ALA H O   1 
ATOM 1568 C CB  . ALA B 2 96  ? 326.405 339.982 480.557 1.00 134.19 ? 96  ALA H CB  1 
ATOM 1569 N N   . LYS B 2 97  ? 325.869 338.183 477.876 1.00 133.11 ? 97  LYS H N   1 
ATOM 1570 C CA  . LYS B 2 97  ? 326.354 337.608 476.632 1.00 133.11 ? 97  LYS H CA  1 
ATOM 1571 C C   . LYS B 2 97  ? 327.398 338.517 476.005 1.00 133.11 ? 97  LYS H C   1 
ATOM 1572 O O   . LYS B 2 97  ? 327.427 339.723 476.251 1.00 133.11 ? 97  LYS H O   1 
ATOM 1573 C CB  . LYS B 2 97  ? 325.205 337.368 475.651 1.00 133.11 ? 97  LYS H CB  1 
ATOM 1574 C CG  . LYS B 2 97  ? 324.506 338.618 475.171 1.00 133.11 ? 97  LYS H CG  1 
ATOM 1575 C CD  . LYS B 2 97  ? 323.338 338.279 474.265 1.00 133.11 ? 97  LYS H CD  1 
ATOM 1576 C CE  . LYS B 2 97  ? 323.797 337.852 472.886 1.00 133.11 ? 97  LYS H CE  1 
ATOM 1577 N NZ  . LYS B 2 97  ? 324.233 339.007 472.063 1.00 133.11 ? 97  LYS H NZ  1 
ATOM 1578 N N   . GLY B 2 98  ? 328.291 337.914 475.221 1.00 129.08 ? 98  GLY H N   1 
ATOM 1579 C CA  . GLY B 2 98  ? 329.360 338.620 474.574 1.00 129.08 ? 98  GLY H CA  1 
ATOM 1580 C C   . GLY B 2 98  ? 329.170 338.726 473.077 1.00 129.08 ? 98  GLY H C   1 
ATOM 1581 O O   . GLY B 2 98  ? 328.088 338.453 472.540 1.00 129.08 ? 98  GLY H O   1 
ATOM 1582 N N   . ASP B 2 99  ? 330.250 339.125 472.396 1.00 129.28 ? 99  ASP H N   1 
ATOM 1583 C CA  . ASP B 2 99  ? 330.323 339.270 470.937 1.00 129.28 ? 99  ASP H CA  1 
ATOM 1584 C C   . ASP B 2 99  ? 329.279 340.251 470.401 1.00 129.28 ? 99  ASP H C   1 
ATOM 1585 O O   . ASP B 2 99  ? 328.439 339.909 469.567 1.00 129.28 ? 99  ASP H O   1 
ATOM 1586 C CB  . ASP B 2 99  ? 330.223 337.914 470.233 1.00 129.28 ? 99  ASP H CB  1 
ATOM 1587 C CG  . ASP B 2 99  ? 331.510 337.121 470.319 1.00 129.28 ? 99  ASP H CG  1 
ATOM 1588 O OD1 . ASP B 2 99  ? 332.425 337.374 469.509 1.00 129.28 ? 99  ASP H OD1 1 
ATOM 1589 O OD2 . ASP B 2 99  ? 331.611 336.244 471.201 1.00 129.28 ? 99  ASP H OD2 1 
ATOM 1590 N N   . TYR B 2 100 ? 329.338 341.486 470.894 1.00 125.11 ? 100 TYR H N   1 
ATOM 1591 C CA  . TYR B 2 100 ? 328.533 342.578 470.352 1.00 125.11 ? 100 TYR H CA  1 
ATOM 1592 C C   . TYR B 2 100 ? 329.181 343.021 469.053 1.00 125.11 ? 100 TYR H C   1 
ATOM 1593 O O   . TYR B 2 100 ? 330.178 343.745 469.068 1.00 125.11 ? 100 TYR H O   1 
ATOM 1594 C CB  . TYR B 2 100 ? 328.438 343.729 471.344 1.00 125.11 ? 100 TYR H CB  1 
ATOM 1595 C CG  . TYR B 2 100 ? 327.492 344.832 470.926 1.00 125.11 ? 100 TYR H CG  1 
ATOM 1596 C CD1 . TYR B 2 100 ? 326.136 344.591 470.776 1.00 125.11 ? 100 TYR H CD1 1 
ATOM 1597 C CD2 . TYR B 2 100 ? 327.953 346.113 470.690 1.00 125.11 ? 100 TYR H CD2 1 
ATOM 1598 C CE1 . TYR B 2 100 ? 325.267 345.583 470.403 1.00 125.11 ? 100 TYR H CE1 1 
ATOM 1599 C CE2 . TYR B 2 100 ? 327.085 347.119 470.315 1.00 125.11 ? 100 TYR H CE2 1 
ATOM 1600 C CZ  . TYR B 2 100 ? 325.744 346.844 470.173 1.00 125.11 ? 100 TYR H CZ  1 
ATOM 1601 O OH  . TYR B 2 100 ? 324.869 347.835 469.798 1.00 125.11 ? 100 TYR H OH  1 
ATOM 1602 N N   . TYR B 2 101 ? 328.614 342.557 467.933 1.00 118.25 ? 101 TYR H N   1 
ATOM 1603 C CA  . TYR B 2 101 ? 329.115 342.805 466.575 1.00 118.25 ? 101 TYR H CA  1 
ATOM 1604 C C   . TYR B 2 101 ? 330.556 342.332 466.409 1.00 118.25 ? 101 TYR H C   1 
ATOM 1605 O O   . TYR B 2 101 ? 331.353 342.943 465.700 1.00 118.25 ? 101 TYR H O   1 
ATOM 1606 C CB  . TYR B 2 101 ? 328.968 344.276 466.177 1.00 118.25 ? 101 TYR H CB  1 
ATOM 1607 C CG  . TYR B 2 101 ? 327.535 344.735 466.117 1.00 118.25 ? 101 TYR H CG  1 
ATOM 1608 C CD1 . TYR B 2 101 ? 326.527 343.871 465.714 1.00 118.25 ? 101 TYR H CD1 1 
ATOM 1609 C CD2 . TYR B 2 101 ? 327.186 346.028 466.471 1.00 118.25 ? 101 TYR H CD2 1 
ATOM 1610 C CE1 . TYR B 2 101 ? 325.212 344.284 465.660 1.00 118.25 ? 101 TYR H CE1 1 
ATOM 1611 C CE2 . TYR B 2 101 ? 325.872 346.451 466.422 1.00 118.25 ? 101 TYR H CE2 1 
ATOM 1612 C CZ  . TYR B 2 101 ? 324.891 345.574 466.015 1.00 118.25 ? 101 TYR H CZ  1 
ATOM 1613 O OH  . TYR B 2 101 ? 323.583 345.991 465.965 1.00 118.25 ? 101 TYR H OH  1 
ATOM 1614 N N   . GLY B 2 102 ? 330.890 341.228 467.067 1.00 121.90 ? 102 GLY H N   1 
ATOM 1615 C CA  . GLY B 2 102 ? 332.216 340.664 466.973 1.00 121.90 ? 102 GLY H CA  1 
ATOM 1616 C C   . GLY B 2 102 ? 333.294 341.416 467.713 1.00 121.90 ? 102 GLY H C   1 
ATOM 1617 O O   . GLY B 2 102 ? 334.472 341.249 467.384 1.00 121.90 ? 102 GLY H O   1 
ATOM 1618 N N   . TYR B 2 103 ? 332.942 342.227 468.709 1.00 122.99 ? 103 TYR H N   1 
ATOM 1619 C CA  . TYR B 2 103 ? 333.914 343.050 469.415 1.00 122.99 ? 103 TYR H CA  1 
ATOM 1620 C C   . TYR B 2 103 ? 334.208 342.560 470.822 1.00 122.99 ? 103 TYR H C   1 
ATOM 1621 O O   . TYR B 2 103 ? 334.973 343.219 471.532 1.00 122.99 ? 103 TYR H O   1 
ATOM 1622 C CB  . TYR B 2 103 ? 333.440 344.498 469.486 1.00 122.99 ? 103 TYR H CB  1 
ATOM 1623 C CG  . TYR B 2 103 ? 333.732 345.291 468.251 1.00 122.99 ? 103 TYR H CG  1 
ATOM 1624 C CD1 . TYR B 2 103 ? 334.916 345.993 468.116 1.00 122.99 ? 103 TYR H CD1 1 
ATOM 1625 C CD2 . TYR B 2 103 ? 332.816 345.345 467.220 1.00 122.99 ? 103 TYR H CD2 1 
ATOM 1626 C CE1 . TYR B 2 103 ? 335.178 346.724 466.982 1.00 122.99 ? 103 TYR H CE1 1 
ATOM 1627 C CE2 . TYR B 2 103 ? 333.065 346.072 466.084 1.00 122.99 ? 103 TYR H CE2 1 
ATOM 1628 C CZ  . TYR B 2 103 ? 334.245 346.759 465.970 1.00 122.99 ? 103 TYR H CZ  1 
ATOM 1629 O OH  . TYR B 2 103 ? 334.479 347.480 464.827 1.00 122.99 ? 103 TYR H OH  1 
ATOM 1630 N N   . ASP B 2 104 ? 333.604 341.444 471.242 1.00 130.82 ? 104 ASP H N   1 
ATOM 1631 C CA  . ASP B 2 104 ? 333.788 340.822 472.557 1.00 130.82 ? 104 ASP H CA  1 
ATOM 1632 C C   . ASP B 2 104 ? 333.422 341.768 473.703 1.00 130.82 ? 104 ASP H C   1 
ATOM 1633 O O   . ASP B 2 104 ? 334.207 341.953 474.636 1.00 130.82 ? 104 ASP H O   1 
ATOM 1634 C CB  . ASP B 2 104 ? 335.222 340.291 472.729 1.00 130.82 ? 104 ASP H CB  1 
ATOM 1635 C CG  . ASP B 2 104 ? 335.321 339.139 473.719 1.00 130.82 ? 104 ASP H CG  1 
ATOM 1636 O OD1 . ASP B 2 104 ? 334.668 339.167 474.783 1.00 130.82 ? 104 ASP H OD1 1 
ATOM 1637 O OD2 . ASP B 2 104 ? 336.072 338.187 473.422 1.00 130.82 ? 104 ASP H OD2 1 
ATOM 1638 N N   . ALA B 2 105 ? 332.260 342.407 473.636 1.00 129.37 ? 105 ALA H N   1 
ATOM 1639 C CA  . ALA B 2 105 ? 331.760 343.249 474.710 1.00 129.37 ? 105 ALA H CA  1 
ATOM 1640 C C   . ALA B 2 105 ? 330.423 342.711 475.199 1.00 129.37 ? 105 ALA H C   1 
ATOM 1641 O O   . ALA B 2 105 ? 329.769 341.924 474.514 1.00 129.37 ? 105 ALA H O   1 
ATOM 1642 C CB  . ALA B 2 105 ? 331.603 344.699 474.253 1.00 129.37 ? 105 ALA H CB  1 
ATOM 1643 N N   . MET B 2 106 ? 330.019 343.136 476.391 0.83 130.41 ? 106 MET H N   1 
ATOM 1644 C CA  . MET B 2 106 ? 328.768 342.666 476.971 0.83 130.41 ? 106 MET H CA  1 
ATOM 1645 C C   . MET B 2 106 ? 327.578 343.399 476.357 0.83 130.41 ? 106 MET H C   1 
ATOM 1646 O O   . MET B 2 106 ? 327.466 344.623 476.472 0.83 130.41 ? 106 MET H O   1 
ATOM 1647 C CB  . MET B 2 106 ? 328.792 342.826 478.488 0.83 130.41 ? 106 MET H CB  1 
ATOM 1648 C CG  . MET B 2 106 ? 329.424 341.643 479.210 0.83 130.41 ? 106 MET H CG  1 
ATOM 1649 S SD  . MET B 2 106 ? 331.214 341.537 479.115 0.75 130.41 ? 106 MET H SD  1 
ATOM 1650 C CE  . MET B 2 106 ? 331.674 342.719 480.369 0.75 130.41 ? 106 MET H CE  1 
ATOM 1651 N N   . ASP B 2 107 ? 326.685 342.641 475.717 1.00 133.90 ? 107 ASP H N   1 
ATOM 1652 C CA  . ASP B 2 107 ? 325.500 343.210 475.072 1.00 133.90 ? 107 ASP H CA  1 
ATOM 1653 C C   . ASP B 2 107 ? 324.454 343.609 476.104 1.00 133.90 ? 107 ASP H C   1 
ATOM 1654 O O   . ASP B 2 107 ? 324.125 344.788 476.263 1.00 133.90 ? 107 ASP H O   1 
ATOM 1655 C CB  . ASP B 2 107 ? 324.875 342.176 474.131 1.00 133.90 ? 107 ASP H CB  1 
ATOM 1656 C CG  . ASP B 2 107 ? 325.873 341.516 473.224 1.00 133.90 ? 107 ASP H CG  1 
ATOM 1657 O OD1 . ASP B 2 107 ? 326.607 340.621 473.679 1.00 133.90 ? 107 ASP H OD1 1 
ATOM 1658 O OD2 . ASP B 2 107 ? 325.825 341.784 472.017 1.00 133.90 ? 107 ASP H OD2 1 
ATOM 1659 N N   . SER B 2 108 ? 323.927 342.615 476.808 1.00 134.94 ? 108 SER H N   1 
ATOM 1660 C CA  . SER B 2 108 ? 322.807 342.759 477.720 1.00 134.94 ? 108 SER H CA  1 
ATOM 1661 C C   . SER B 2 108 ? 323.016 341.800 478.876 1.00 134.94 ? 108 SER H C   1 
ATOM 1662 O O   . SER B 2 108 ? 323.591 340.723 478.703 1.00 134.94 ? 108 SER H O   1 
ATOM 1663 C CB  . SER B 2 108 ? 321.481 342.471 477.022 1.00 134.94 ? 108 SER H CB  1 
ATOM 1664 O OG  . SER B 2 108 ? 321.576 341.307 476.224 1.00 134.94 ? 108 SER H OG  1 
ATOM 1665 N N   . TRP B 2 109 ? 322.546 342.191 480.049 1.00 137.57 ? 109 TRP H N   1 
ATOM 1666 C CA  . TRP B 2 109 ? 322.908 341.521 481.283 1.00 137.57 ? 109 TRP H CA  1 
ATOM 1667 C C   . TRP B 2 109 ? 321.681 340.874 481.906 1.00 137.57 ? 109 TRP H C   1 
ATOM 1668 O O   . TRP B 2 109 ? 320.541 341.245 481.619 1.00 137.57 ? 109 TRP H O   1 
ATOM 1669 C CB  . TRP B 2 109 ? 323.541 342.506 482.274 1.00 137.57 ? 109 TRP H CB  1 
ATOM 1670 C CG  . TRP B 2 109 ? 324.843 343.135 481.834 1.00 137.57 ? 109 TRP H CG  1 
ATOM 1671 C CD1 . TRP B 2 109 ? 325.083 343.824 480.681 1.00 137.57 ? 109 TRP H CD1 1 
ATOM 1672 C CD2 . TRP B 2 109 ? 326.069 343.157 482.567 1.00 137.57 ? 109 TRP H CD2 1 
ATOM 1673 N NE1 . TRP B 2 109 ? 326.380 344.255 480.645 1.00 137.57 ? 109 TRP H NE1 1 
ATOM 1674 C CE2 . TRP B 2 109 ? 327.007 343.860 481.794 1.00 137.57 ? 109 TRP H CE2 1 
ATOM 1675 C CE3 . TRP B 2 109 ? 326.465 342.646 483.802 1.00 137.57 ? 109 TRP H CE3 1 
ATOM 1676 C CZ2 . TRP B 2 109 ? 328.314 344.062 482.212 1.00 137.57 ? 109 TRP H CZ2 1 
ATOM 1677 C CZ3 . TRP B 2 109 ? 327.762 342.847 484.216 1.00 137.57 ? 109 TRP H CZ3 1 
ATOM 1678 C CH2 . TRP B 2 109 ? 328.672 343.549 483.424 1.00 137.57 ? 109 TRP H CH2 1 
ATOM 1679 N N   . GLY B 2 110 ? 321.928 339.897 482.769 1.00 147.28 ? 110 GLY H N   1 
ATOM 1680 C CA  . GLY B 2 110 ? 320.872 339.286 483.541 1.00 147.28 ? 110 GLY H CA  1 
ATOM 1681 C C   . GLY B 2 110 ? 320.437 340.185 484.680 1.00 147.28 ? 110 GLY H C   1 
ATOM 1682 O O   . GLY B 2 110 ? 320.992 341.259 484.920 1.00 147.28 ? 110 GLY H O   1 
ATOM 1683 N N   . GLN B 2 111 ? 319.416 339.727 485.400 1.00 152.01 ? 111 GLN H N   1 
ATOM 1684 C CA  . GLN B 2 111 ? 318.900 340.515 486.511 1.00 152.01 ? 111 GLN H CA  1 
ATOM 1685 C C   . GLN B 2 111 ? 319.803 340.460 487.735 1.00 152.01 ? 111 GLN H C   1 
ATOM 1686 O O   . GLN B 2 111 ? 319.729 341.356 488.581 1.00 152.01 ? 111 GLN H O   1 
ATOM 1687 C CB  . GLN B 2 111 ? 317.487 340.054 486.875 1.00 152.01 ? 111 GLN H CB  1 
ATOM 1688 C CG  . GLN B 2 111 ? 317.411 338.689 487.531 1.00 152.01 ? 111 GLN H CG  1 
ATOM 1689 C CD  . GLN B 2 111 ? 317.237 337.575 486.526 1.00 152.01 ? 111 GLN H CD  1 
ATOM 1690 O OE1 . GLN B 2 111 ? 317.283 337.801 485.319 1.00 152.01 ? 111 GLN H OE1 1 
ATOM 1691 N NE2 . GLN B 2 111 ? 317.036 336.361 487.020 1.00 152.01 ? 111 GLN H NE2 1 
ATOM 1692 N N   . GLY B 2 112 ? 320.647 339.449 487.846 1.00 154.02 ? 112 GLY H N   1 
ATOM 1693 C CA  . GLY B 2 112 ? 321.554 339.360 488.977 1.00 154.02 ? 112 GLY H CA  1 
ATOM 1694 C C   . GLY B 2 112 ? 320.888 338.774 490.204 1.00 154.02 ? 112 GLY H C   1 
ATOM 1695 O O   . GLY B 2 112 ? 319.814 339.193 490.632 1.00 154.02 ? 112 GLY H O   1 
ATOM 1696 N N   . THR B 2 113 ? 321.549 337.775 490.786 1.00 154.36 ? 113 THR H N   1 
ATOM 1697 C CA  . THR B 2 113 ? 321.074 337.113 491.999 1.00 154.36 ? 113 THR H CA  1 
ATOM 1698 C C   . THR B 2 113 ? 322.104 337.368 493.092 1.00 154.36 ? 113 THR H C   1 
ATOM 1699 O O   . THR B 2 113 ? 323.205 336.812 493.054 1.00 154.36 ? 113 THR H O   1 
ATOM 1700 C CB  . THR B 2 113 ? 320.866 335.617 491.783 1.00 154.36 ? 113 THR H CB  1 
ATOM 1701 O OG1 . THR B 2 113 ? 322.137 334.957 491.759 1.00 154.36 ? 113 THR H OG1 1 
ATOM 1702 C CG2 . THR B 2 113 ? 320.137 335.350 490.480 1.00 154.36 ? 113 THR H CG2 1 
ATOM 1703 N N   . SER B 2 114 ? 321.749 338.207 494.060 1.00 156.79 ? 114 SER H N   1 
ATOM 1704 C CA  . SER B 2 114 ? 322.647 338.515 495.163 1.00 156.79 ? 114 SER H CA  1 
ATOM 1705 C C   . SER B 2 114 ? 322.725 337.332 496.114 1.00 156.79 ? 114 SER H C   1 
ATOM 1706 O O   . SER B 2 114 ? 321.706 336.712 496.429 1.00 156.79 ? 114 SER H O   1 
ATOM 1707 C CB  . SER B 2 114 ? 322.172 339.759 495.908 1.00 156.79 ? 114 SER H CB  1 
ATOM 1708 O OG  . SER B 2 114 ? 322.694 339.786 497.224 1.00 156.79 ? 114 SER H OG  1 
ATOM 1709 N N   . VAL B 2 115 ? 323.936 337.009 496.563 1.00 159.92 ? 115 VAL H N   1 
ATOM 1710 C CA  . VAL B 2 115 ? 324.128 335.919 497.506 1.00 159.92 ? 115 VAL H CA  1 
ATOM 1711 C C   . VAL B 2 115 ? 324.699 336.470 498.805 1.00 159.92 ? 115 VAL H C   1 
ATOM 1712 O O   . VAL B 2 115 ? 325.306 337.544 498.852 1.00 159.92 ? 115 VAL H O   1 
ATOM 1713 C CB  . VAL B 2 115 ? 325.027 334.796 496.946 1.00 159.92 ? 115 VAL H CB  1 
ATOM 1714 C CG1 . VAL B 2 115 ? 324.537 334.351 495.581 1.00 159.92 ? 115 VAL H CG1 1 
ATOM 1715 C CG2 . VAL B 2 115 ? 326.475 335.238 496.877 1.00 159.92 ? 115 VAL H CG2 1 
ATOM 1716 N N   . THR B 2 116 ? 324.454 335.725 499.882 1.00 167.97 ? 116 THR H N   1 
ATOM 1717 C CA  . THR B 2 116 ? 325.024 335.990 501.196 1.00 167.97 ? 116 THR H CA  1 
ATOM 1718 C C   . THR B 2 116 ? 325.599 334.684 501.714 1.00 167.97 ? 116 THR H C   1 
ATOM 1719 O O   . THR B 2 116 ? 324.900 333.667 501.748 1.00 167.97 ? 116 THR H O   1 
ATOM 1720 C CB  . THR B 2 116 ? 323.982 336.535 502.182 1.00 167.97 ? 116 THR H CB  1 
ATOM 1721 O OG1 . THR B 2 116 ? 322.892 335.613 502.288 1.00 167.97 ? 116 THR H OG1 1 
ATOM 1722 C CG2 . THR B 2 116 ? 323.463 337.900 501.748 1.00 167.97 ? 116 THR H CG2 1 
ATOM 1723 N N   . VAL B 2 117 ? 326.871 334.711 502.114 1.00 171.27 ? 117 VAL H N   1 
ATOM 1724 C CA  . VAL B 2 117 ? 327.605 333.484 502.385 1.00 171.27 ? 117 VAL H CA  1 
ATOM 1725 C C   . VAL B 2 117 ? 327.571 333.105 503.862 1.00 171.27 ? 117 VAL H C   1 
ATOM 1726 O O   . VAL B 2 117 ? 327.860 331.952 504.205 1.00 171.27 ? 117 VAL H O   1 
ATOM 1727 C CB  . VAL B 2 117 ? 329.057 333.619 501.872 1.00 171.27 ? 117 VAL H CB  1 
ATOM 1728 C CG1 . VAL B 2 117 ? 329.883 334.525 502.770 1.00 171.27 ? 117 VAL H CG1 1 
ATOM 1729 C CG2 . VAL B 2 117 ? 329.715 332.273 501.622 1.00 171.27 ? 117 VAL H CG2 1 
ATOM 1730 N N   . SER B 2 118 ? 327.183 334.027 504.741 1.00 177.83 ? 118 SER H N   1 
ATOM 1731 C CA  . SER B 2 118 ? 327.235 333.789 506.177 1.00 177.83 ? 118 SER H CA  1 
ATOM 1732 C C   . SER B 2 118 ? 326.137 332.836 506.626 1.00 177.83 ? 118 SER H C   1 
ATOM 1733 O O   . SER B 2 118 ? 324.980 332.964 506.239 1.00 177.83 ? 118 SER H O   1 
ATOM 1734 C CB  . SER B 2 118 ? 327.113 335.108 506.938 1.00 177.83 ? 118 SER H CB  1 
ATOM 1735 O OG  . SER B 2 118 ? 326.986 334.880 508.330 1.00 177.83 ? 118 SER H OG  1 
ATOM 1736 N N   . ARG B 2 119 ? 326.411 332.153 507.757 1.00 178.63 ? 119 ARG H N   1 
ATOM 1737 C CA  . ARG B 2 119 ? 325.350 331.731 508.757 1.00 178.63 ? 119 ARG H CA  1 
ATOM 1738 C C   . ARG B 2 119 ? 324.673 332.938 509.398 1.00 178.63 ? 119 ARG H C   1 
ATOM 1739 O O   . ARG B 2 119 ? 323.454 332.959 509.575 1.00 178.63 ? 119 ARG H O   1 
ATOM 1740 C CB  . ARG B 2 119 ? 325.954 330.834 509.844 1.00 178.63 ? 119 ARG H CB  1 
ATOM 1741 C CG  . ARG B 2 119 ? 324.939 330.275 510.829 1.00 178.63 ? 119 ARG H CG  1 
ATOM 1742 C CD  . ARG B 2 119 ? 323.799 329.567 510.113 1.00 178.63 ? 119 ARG H CD  1 
ATOM 1743 N NE  . ARG B 2 119 ? 322.687 329.273 511.012 1.00 178.63 ? 119 ARG H NE  1 
ATOM 1744 C CZ  . ARG B 2 119 ? 321.670 330.099 511.239 1.00 178.63 ? 119 ARG H CZ  1 
ATOM 1745 N NH1 . ARG B 2 119 ? 320.701 329.748 512.074 1.00 178.63 ? 119 ARG H NH1 1 
ATOM 1746 N NH2 . ARG B 2 119 ? 321.622 331.277 510.631 1.00 178.63 ? 119 ARG H NH2 1 
ATOM 1747 N N   . SER C 3 58  ? 359.043 344.911 424.481 1.00 129.74 ? 58  SER A N   1 
ATOM 1748 C CA  . SER C 3 58  ? 359.708 344.147 425.528 1.00 129.74 ? 58  SER A CA  1 
ATOM 1749 C C   . SER C 3 58  ? 358.713 343.711 426.581 1.00 129.74 ? 58  SER A C   1 
ATOM 1750 O O   . SER C 3 58  ? 358.733 344.196 427.707 1.00 129.74 ? 58  SER A O   1 
ATOM 1751 C CB  . SER C 3 58  ? 360.820 344.965 426.176 1.00 129.74 ? 58  SER A CB  1 
ATOM 1752 O OG  . SER C 3 58  ? 361.412 344.245 427.242 1.00 129.74 ? 58  SER A OG  1 
ATOM 1753 N N   . ARG C 3 59  ? 357.841 342.785 426.205 1.00 129.40 ? 59  ARG A N   1 
ATOM 1754 C CA  . ARG C 3 59  ? 356.760 342.348 427.070 1.00 129.40 ? 59  ARG A CA  1 
ATOM 1755 C C   . ARG C 3 59  ? 356.849 340.868 427.404 1.00 129.40 ? 59  ARG A C   1 
ATOM 1756 O O   . ARG C 3 59  ? 355.941 340.338 428.048 1.00 129.40 ? 59  ARG A O   1 
ATOM 1757 C CB  . ARG C 3 59  ? 355.400 342.650 426.416 1.00 129.40 ? 59  ARG A CB  1 
ATOM 1758 C CG  . ARG C 3 59  ? 355.040 344.146 426.296 1.00 129.40 ? 59  ARG A CG  1 
ATOM 1759 C CD  . ARG C 3 59  ? 355.576 344.795 425.002 1.00 129.40 ? 59  ARG A CD  1 
ATOM 1760 N NE  . ARG C 3 59  ? 355.273 346.221 424.892 1.00 129.40 ? 59  ARG A NE  1 
ATOM 1761 C CZ  . ARG C 3 59  ? 355.845 347.039 424.013 1.00 129.40 ? 59  ARG A CZ  1 
ATOM 1762 N NH1 . ARG C 3 59  ? 356.758 346.578 423.171 1.00 129.40 ? 59  ARG A NH1 1 
ATOM 1763 N NH2 . ARG C 3 59  ? 355.510 348.321 423.978 1.00 129.40 ? 59  ARG A NH2 1 
ATOM 1764 N N   . SER C 3 60  ? 357.920 340.197 426.980 1.00 127.08 ? 60  SER A N   1 
ATOM 1765 C CA  . SER C 3 60  ? 358.014 338.750 427.100 1.00 127.08 ? 60  SER A CA  1 
ATOM 1766 C C   . SER C 3 60  ? 358.732 338.297 428.357 1.00 127.08 ? 60  SER A C   1 
ATOM 1767 O O   . SER C 3 60  ? 358.619 337.125 428.723 1.00 127.08 ? 60  SER A O   1 
ATOM 1768 C CB  . SER C 3 60  ? 358.736 338.167 425.892 1.00 127.08 ? 60  SER A CB  1 
ATOM 1769 O OG  . SER C 3 60  ? 360.134 338.155 426.114 1.00 127.08 ? 60  SER A OG  1 
ATOM 1770 N N   . GLU C 3 61  ? 359.465 339.181 429.029 1.00 125.58 ? 61  GLU A N   1 
ATOM 1771 C CA  . GLU C 3 61  ? 360.164 338.773 430.239 1.00 125.58 ? 61  GLU A CA  1 
ATOM 1772 C C   . GLU C 3 61  ? 359.230 338.724 431.446 1.00 125.58 ? 61  GLU A C   1 
ATOM 1773 O O   . GLU C 3 61  ? 359.636 338.282 432.526 1.00 125.58 ? 61  GLU A O   1 
ATOM 1774 C CB  . GLU C 3 61  ? 361.358 339.707 430.474 1.00 125.58 ? 61  GLU A CB  1 
ATOM 1775 C CG  . GLU C 3 61  ? 362.454 339.160 431.389 1.00 125.58 ? 61  GLU A CG  1 
ATOM 1776 C CD  . GLU C 3 61  ? 363.611 340.117 431.554 1.00 125.58 ? 61  GLU A CD  1 
ATOM 1777 O OE1 . GLU C 3 61  ? 363.613 341.154 430.866 1.00 125.58 ? 61  GLU A OE1 1 
ATOM 1778 O OE2 . GLU C 3 61  ? 364.507 339.839 432.380 1.00 125.58 ? 61  GLU A OE2 1 
ATOM 1779 N N   . SER C 3 62  ? 357.972 339.126 431.278 1.00 117.32 ? 62  SER A N   1 
ATOM 1780 C CA  . SER C 3 62  ? 356.959 338.984 432.310 1.00 117.32 ? 62  SER A CA  1 
ATOM 1781 C C   . SER C 3 62  ? 356.073 337.768 432.093 1.00 117.32 ? 62  SER A C   1 
ATOM 1782 O O   . SER C 3 62  ? 355.015 337.668 432.717 1.00 117.32 ? 62  SER A O   1 
ATOM 1783 C CB  . SER C 3 62  ? 356.101 340.245 432.384 1.00 117.32 ? 62  SER A CB  1 
ATOM 1784 O OG  . SER C 3 62  ? 355.200 340.304 431.297 1.00 117.32 ? 62  SER A OG  1 
ATOM 1785 N N   . SER C 3 63  ? 356.473 336.847 431.223 1.00 113.23 ? 63  SER A N   1 
ATOM 1786 C CA  . SER C 3 63  ? 355.750 335.596 431.084 1.00 113.23 ? 63  SER A CA  1 
ATOM 1787 C C   . SER C 3 63  ? 355.973 334.723 432.313 1.00 113.23 ? 63  SER A C   1 
ATOM 1788 O O   . SER C 3 63  ? 356.917 334.916 433.076 1.00 113.23 ? 63  SER A O   1 
ATOM 1789 C CB  . SER C 3 63  ? 356.196 334.854 429.830 1.00 113.23 ? 63  SER A CB  1 
ATOM 1790 O OG  . SER C 3 63  ? 355.553 333.599 429.739 1.00 113.23 ? 63  SER A OG  1 
ATOM 1791 N N   . ILE C 3 64  ? 355.089 333.739 432.495 1.00 110.30 ? 64  ILE A N   1 
ATOM 1792 C CA  . ILE C 3 64  ? 355.151 332.885 433.679 1.00 110.30 ? 64  ILE A CA  1 
ATOM 1793 C C   . ILE C 3 64  ? 356.356 331.954 433.608 1.00 110.30 ? 64  ILE A C   1 
ATOM 1794 O O   . ILE C 3 64  ? 356.968 331.626 434.632 1.00 110.30 ? 64  ILE A O   1 
ATOM 1795 C CB  . ILE C 3 64  ? 353.826 332.115 433.835 1.00 110.30 ? 64  ILE A CB  1 
ATOM 1796 C CG1 . ILE C 3 64  ? 352.671 333.100 433.939 1.00 110.30 ? 64  ILE A CG1 1 
ATOM 1797 C CG2 . ILE C 3 64  ? 353.811 331.266 435.082 1.00 110.30 ? 64  ILE A CG2 1 
ATOM 1798 C CD1 . ILE C 3 64  ? 352.802 334.054 435.096 1.00 110.30 ? 64  ILE A CD1 1 
ATOM 1799 N N   . GLU C 3 65  ? 356.744 331.554 432.397 1.00 116.57 ? 65  GLU A N   1 
ATOM 1800 C CA  . GLU C 3 65  ? 357.927 330.717 432.232 1.00 116.57 ? 65  GLU A CA  1 
ATOM 1801 C C   . GLU C 3 65  ? 359.203 331.476 432.581 1.00 116.57 ? 65  GLU A C   1 
ATOM 1802 O O   . GLU C 3 65  ? 360.134 330.901 433.151 1.00 116.57 ? 65  GLU A O   1 
ATOM 1803 C CB  . GLU C 3 65  ? 357.990 330.187 430.802 1.00 116.57 ? 65  GLU A CB  1 
ATOM 1804 C CG  . GLU C 3 65  ? 359.081 329.164 430.550 1.00 116.57 ? 65  GLU A CG  1 
ATOM 1805 C CD  . GLU C 3 65  ? 358.758 327.804 431.128 1.00 116.57 ? 65  GLU A CD  1 
ATOM 1806 O OE1 . GLU C 3 65  ? 359.004 327.592 432.333 1.00 116.57 ? 65  GLU A OE1 1 
ATOM 1807 O OE2 . GLU C 3 65  ? 358.262 326.941 430.375 1.00 116.57 ? 65  GLU A OE2 1 
ATOM 1808 N N   . ASN C 3 66  ? 359.261 332.768 432.266 1.00 115.36 ? 66  ASN A N   1 
ATOM 1809 C CA  . ASN C 3 66  ? 360.455 333.541 432.581 1.00 115.36 ? 66  ASN A CA  1 
ATOM 1810 C C   . ASN C 3 66  ? 360.413 334.131 433.981 1.00 115.36 ? 66  ASN A C   1 
ATOM 1811 O O   . ASN C 3 66  ? 361.405 334.720 434.418 1.00 115.36 ? 66  ASN A O   1 
ATOM 1812 C CB  . ASN C 3 66  ? 360.643 334.657 431.560 1.00 115.36 ? 66  ASN A CB  1 
ATOM 1813 C CG  . ASN C 3 66  ? 360.744 334.137 430.150 1.00 115.36 ? 66  ASN A CG  1 
ATOM 1814 O OD1 . ASN C 3 66  ? 361.830 333.823 429.671 1.00 115.36 ? 66  ASN A OD1 1 
ATOM 1815 N ND2 . ASN C 3 66  ? 359.610 334.042 429.471 1.00 115.36 ? 66  ASN A ND2 1 
ATOM 1816 N N   . PHE C 3 67  ? 359.297 333.991 434.689 1.00 109.00 ? 67  PHE A N   1 
ATOM 1817 C CA  . PHE C 3 67  ? 359.160 334.562 436.021 1.00 109.00 ? 67  PHE A CA  1 
ATOM 1818 C C   . PHE C 3 67  ? 359.371 333.537 437.123 1.00 109.00 ? 67  PHE A C   1 
ATOM 1819 O O   . PHE C 3 67  ? 359.823 333.899 438.215 1.00 109.00 ? 67  PHE A O   1 
ATOM 1820 C CB  . PHE C 3 67  ? 357.779 335.204 436.165 1.00 109.00 ? 67  PHE A CB  1 
ATOM 1821 C CG  . PHE C 3 67  ? 357.531 335.836 437.493 1.00 109.00 ? 67  PHE A CG  1 
ATOM 1822 C CD1 . PHE C 3 67  ? 358.243 336.946 437.888 1.00 109.00 ? 67  PHE A CD1 1 
ATOM 1823 C CD2 . PHE C 3 67  ? 356.564 335.332 438.336 1.00 109.00 ? 67  PHE A CD2 1 
ATOM 1824 C CE1 . PHE C 3 67  ? 358.006 337.534 439.110 1.00 109.00 ? 67  PHE A CE1 1 
ATOM 1825 C CE2 . PHE C 3 67  ? 356.324 335.912 439.559 1.00 109.00 ? 67  PHE A CE2 1 
ATOM 1826 C CZ  . PHE C 3 67  ? 357.045 337.015 439.945 1.00 109.00 ? 67  PHE A CZ  1 
ATOM 1827 N N   . LEU C 3 68  ? 359.079 332.267 436.866 1.00 108.10 ? 68  LEU A N   1 
ATOM 1828 C CA  . LEU C 3 68  ? 359.150 331.247 437.901 1.00 108.10 ? 68  LEU A CA  1 
ATOM 1829 C C   . LEU C 3 68  ? 360.196 330.172 437.662 1.00 108.10 ? 68  LEU A C   1 
ATOM 1830 O O   . LEU C 3 68  ? 360.561 329.480 438.610 1.00 108.10 ? 68  LEU A O   1 
ATOM 1831 C CB  . LEU C 3 68  ? 357.786 330.568 438.070 1.00 108.10 ? 68  LEU A CB  1 
ATOM 1832 C CG  . LEU C 3 68  ? 356.676 331.460 438.607 1.00 108.10 ? 68  LEU A CG  1 
ATOM 1833 C CD1 . LEU C 3 68  ? 355.435 330.647 438.869 1.00 108.10 ? 68  LEU A CD1 1 
ATOM 1834 C CD2 . LEU C 3 68  ? 357.140 332.137 439.868 1.00 108.10 ? 68  LEU A CD2 1 
ATOM 1835 N N   . CYS C 3 69  ? 360.681 329.998 436.434 1.00 111.07 ? 69  CYS A N   1 
ATOM 1836 C CA  . CYS C 3 69  ? 361.696 328.983 436.161 1.00 111.07 ? 69  CYS A CA  1 
ATOM 1837 C C   . CYS C 3 69  ? 363.065 329.604 436.434 1.00 111.07 ? 69  CYS A C   1 
ATOM 1838 O O   . CYS C 3 69  ? 363.787 330.045 435.538 1.00 111.07 ? 69  CYS A O   1 
ATOM 1839 C CB  . CYS C 3 69  ? 361.560 328.457 434.738 1.00 111.07 ? 69  CYS A CB  1 
ATOM 1840 S SG  . CYS C 3 69  ? 362.860 327.337 434.157 1.00 111.07 ? 69  CYS A SG  1 
ATOM 1841 N N   . ARG C 3 70  ? 363.403 329.685 437.721 1.00 104.94 ? 70  ARG A N   1 
ATOM 1842 C CA  . ARG C 3 70  ? 364.714 330.150 438.155 1.00 104.94 ? 70  ARG A CA  1 
ATOM 1843 C C   . ARG C 3 70  ? 365.285 329.177 439.177 1.00 104.94 ? 70  ARG A C   1 
ATOM 1844 O O   . ARG C 3 70  ? 364.594 328.248 439.603 1.00 104.94 ? 70  ARG A O   1 
ATOM 1845 C CB  . ARG C 3 70  ? 364.635 331.553 438.760 1.00 104.94 ? 70  ARG A CB  1 
ATOM 1846 C CG  . ARG C 3 70  ? 363.904 332.586 437.924 1.00 104.94 ? 70  ARG A CG  1 
ATOM 1847 C CD  . ARG C 3 70  ? 364.823 333.273 436.944 1.00 104.94 ? 70  ARG A CD  1 
ATOM 1848 N NE  . ARG C 3 70  ? 364.065 334.025 435.952 1.00 104.94 ? 70  ARG A NE  1 
ATOM 1849 C CZ  . ARG C 3 70  ? 364.508 335.117 435.345 1.00 104.94 ? 70  ARG A CZ  1 
ATOM 1850 N NH1 . ARG C 3 70  ? 365.707 335.595 435.634 1.00 104.94 ? 70  ARG A NH1 1 
ATOM 1851 N NH2 . ARG C 3 70  ? 363.751 335.734 434.453 1.00 104.94 ? 70  ARG A NH2 1 
ATOM 1852 N N   . SER C 3 71  ? 366.532 329.381 439.589 1.00 103.48 ? 71  SER A N   1 
ATOM 1853 C CA  . SER C 3 71  ? 367.178 328.515 440.562 1.00 103.48 ? 71  SER A CA  1 
ATOM 1854 C C   . SER C 3 71  ? 367.327 329.251 441.882 1.00 103.48 ? 71  SER A C   1 
ATOM 1855 O O   . SER C 3 71  ? 367.634 330.444 441.912 1.00 103.48 ? 71  SER A O   1 
ATOM 1856 C CB  . SER C 3 71  ? 368.547 328.047 440.076 1.00 103.48 ? 71  SER A CB  1 
ATOM 1857 O OG  . SER C 3 71  ? 368.449 327.432 438.807 1.00 103.48 ? 71  SER A OG  1 
ATOM 1858 N N   . ALA C 3 72  ? 367.119 328.527 442.979 1.00 101.59 ? 72  ALA A N   1 
ATOM 1859 C CA  . ALA C 3 72  ? 367.165 329.136 444.301 1.00 101.59 ? 72  ALA A CA  1 
ATOM 1860 C C   . ALA C 3 72  ? 367.757 328.147 445.289 1.00 101.59 ? 72  ALA A C   1 
ATOM 1861 O O   . ALA C 3 72  ? 367.455 326.955 445.221 1.00 101.59 ? 72  ALA A O   1 
ATOM 1862 C CB  . ALA C 3 72  ? 365.768 329.562 444.752 1.00 101.59 ? 72  ALA A CB  1 
ATOM 1863 N N   . CYS C 3 73  ? 368.596 328.637 446.197 1.00 103.01 ? 73  CYS A N   1 
ATOM 1864 C CA  . CYS C 3 73  ? 369.129 327.794 447.261 1.00 103.01 ? 73  CYS A CA  1 
ATOM 1865 C C   . CYS C 3 73  ? 368.082 327.666 448.356 1.00 103.01 ? 73  CYS A C   1 
ATOM 1866 O O   . CYS C 3 73  ? 367.798 328.634 449.065 1.00 103.01 ? 73  CYS A O   1 
ATOM 1867 C CB  . CYS C 3 73  ? 370.422 328.380 447.814 1.00 103.01 ? 73  CYS A CB  1 
ATOM 1868 S SG  . CYS C 3 73  ? 370.924 327.698 449.409 1.00 103.01 ? 73  CYS A SG  1 
ATOM 1869 N N   . VAL C 3 74  ? 367.501 326.477 448.498 1.00 100.93 ? 74  VAL A N   1 
ATOM 1870 C CA  . VAL C 3 74  ? 366.404 326.291 449.437 1.00 100.93 ? 74  VAL A CA  1 
ATOM 1871 C C   . VAL C 3 74  ? 366.825 325.631 450.746 1.00 100.93 ? 74  VAL A C   1 
ATOM 1872 O O   . VAL C 3 74  ? 366.216 325.916 451.787 1.00 100.93 ? 74  VAL A O   1 
ATOM 1873 C CB  . VAL C 3 74  ? 365.254 325.496 448.789 1.00 100.93 ? 74  VAL A CB  1 
ATOM 1874 C CG1 . VAL C 3 74  ? 364.540 326.349 447.774 1.00 100.93 ? 74  VAL A CG1 1 
ATOM 1875 C CG2 . VAL C 3 74  ? 365.782 324.263 448.122 1.00 100.93 ? 74  VAL A CG2 1 
ATOM 1876 N N   . TYR C 3 75  ? 367.846 324.782 450.738 1.00 104.84 ? 75  TYR A N   1 
ATOM 1877 C CA  . TYR C 3 75  ? 368.222 324.060 451.941 1.00 104.84 ? 75  TYR A CA  1 
ATOM 1878 C C   . TYR C 3 75  ? 369.734 324.013 452.066 1.00 104.84 ? 75  TYR A C   1 
ATOM 1879 O O   . TYR C 3 75  ? 370.456 324.084 451.071 1.00 104.84 ? 75  TYR A O   1 
ATOM 1880 C CB  . TYR C 3 75  ? 367.661 322.641 451.941 1.00 104.84 ? 75  TYR A CB  1 
ATOM 1881 C CG  . TYR C 3 75  ? 367.549 322.046 453.315 1.00 104.84 ? 75  TYR A CG  1 
ATOM 1882 C CD1 . TYR C 3 75  ? 366.876 322.715 454.324 1.00 104.84 ? 75  TYR A CD1 1 
ATOM 1883 C CD2 . TYR C 3 75  ? 368.118 320.819 453.607 1.00 104.84 ? 75  TYR A CD2 1 
ATOM 1884 C CE1 . TYR C 3 75  ? 366.770 322.179 455.586 1.00 104.84 ? 75  TYR A CE1 1 
ATOM 1885 C CE2 . TYR C 3 75  ? 368.019 320.274 454.864 1.00 104.84 ? 75  TYR A CE2 1 
ATOM 1886 C CZ  . TYR C 3 75  ? 367.343 320.958 455.851 1.00 104.84 ? 75  TYR A CZ  1 
ATOM 1887 O OH  . TYR C 3 75  ? 367.239 320.421 457.112 1.00 104.84 ? 75  TYR A OH  1 
ATOM 1888 N N   . TYR C 3 76  ? 370.202 323.883 453.304 1.00 108.05 ? 76  TYR A N   1 
ATOM 1889 C CA  . TYR C 3 76  ? 371.635 323.855 453.581 1.00 108.05 ? 76  TYR A CA  1 
ATOM 1890 C C   . TYR C 3 76  ? 371.832 323.111 454.893 1.00 108.05 ? 76  TYR A C   1 
ATOM 1891 O O   . TYR C 3 76  ? 371.458 323.622 455.952 1.00 108.05 ? 76  TYR A O   1 
ATOM 1892 C CB  . TYR C 3 76  ? 372.193 325.269 453.649 1.00 108.05 ? 76  TYR A CB  1 
ATOM 1893 C CG  . TYR C 3 76  ? 373.528 325.374 454.334 1.00 108.05 ? 76  TYR A CG  1 
ATOM 1894 C CD1 . TYR C 3 76  ? 374.670 324.862 453.744 1.00 108.05 ? 76  TYR A CD1 1 
ATOM 1895 C CD2 . TYR C 3 76  ? 373.647 325.993 455.569 1.00 108.05 ? 76  TYR A CD2 1 
ATOM 1896 C CE1 . TYR C 3 76  ? 375.897 324.955 454.367 1.00 108.05 ? 76  TYR A CE1 1 
ATOM 1897 C CE2 . TYR C 3 76  ? 374.869 326.091 456.200 1.00 108.05 ? 76  TYR A CE2 1 
ATOM 1898 C CZ  . TYR C 3 76  ? 375.990 325.570 455.593 1.00 108.05 ? 76  TYR A CZ  1 
ATOM 1899 O OH  . TYR C 3 76  ? 377.212 325.663 456.215 1.00 108.05 ? 76  TYR A OH  1 
ATOM 1900 N N   . ALA C 3 77  ? 372.406 321.912 454.826 1.00 108.72 ? 77  ALA A N   1 
ATOM 1901 C CA  . ALA C 3 77  ? 372.539 321.059 455.997 1.00 108.72 ? 77  ALA A CA  1 
ATOM 1902 C C   . ALA C 3 77  ? 373.920 320.424 456.020 1.00 108.72 ? 77  ALA A C   1 
ATOM 1903 O O   . ALA C 3 77  ? 374.579 320.289 454.990 1.00 108.72 ? 77  ALA A O   1 
ATOM 1904 C CB  . ALA C 3 77  ? 371.467 319.968 456.021 1.00 108.72 ? 77  ALA A CB  1 
ATOM 1905 N N   . THR C 3 78  ? 374.351 320.033 457.215 1.00 108.69 ? 78  THR A N   1 
ATOM 1906 C CA  . THR C 3 78  ? 375.639 319.389 457.422 1.00 108.69 ? 78  THR A CA  1 
ATOM 1907 C C   . THR C 3 78  ? 375.450 317.982 457.972 1.00 108.69 ? 78  THR A C   1 
ATOM 1908 O O   . THR C 3 78  ? 374.489 317.696 458.688 1.00 108.69 ? 78  THR A O   1 
ATOM 1909 C CB  . THR C 3 78  ? 376.515 320.182 458.395 1.00 108.69 ? 78  THR A CB  1 
ATOM 1910 O OG1 . THR C 3 78  ? 376.121 319.881 459.736 1.00 108.69 ? 78  THR A OG1 1 
ATOM 1911 C CG2 . THR C 3 78  ? 376.377 321.671 458.166 1.00 108.69 ? 78  THR A CG2 1 
ATOM 1912 N N   . TYR C 3 79  ? 376.395 317.106 457.639 1.00 107.29 ? 79  TYR A N   1 
ATOM 1913 C CA  . TYR C 3 79  ? 376.412 315.754 458.178 1.00 107.29 ? 79  TYR A CA  1 
ATOM 1914 C C   . TYR C 3 79  ? 377.832 315.218 458.118 1.00 107.29 ? 79  TYR A C   1 
ATOM 1915 O O   . TYR C 3 79  ? 378.561 315.495 457.166 1.00 107.29 ? 79  TYR A O   1 
ATOM 1916 C CB  . TYR C 3 79  ? 375.461 314.820 457.419 1.00 107.29 ? 79  TYR A CB  1 
ATOM 1917 C CG  . TYR C 3 79  ? 375.716 314.698 455.935 1.00 107.29 ? 79  TYR A CG  1 
ATOM 1918 C CD1 . TYR C 3 79  ? 375.124 315.569 455.040 1.00 107.29 ? 79  TYR A CD1 1 
ATOM 1919 C CD2 . TYR C 3 79  ? 376.516 313.689 455.428 1.00 107.29 ? 79  TYR A CD2 1 
ATOM 1920 C CE1 . TYR C 3 79  ? 375.343 315.455 453.691 1.00 107.29 ? 79  TYR A CE1 1 
ATOM 1921 C CE2 . TYR C 3 79  ? 376.740 313.571 454.084 1.00 107.29 ? 79  TYR A CE2 1 
ATOM 1922 C CZ  . TYR C 3 79  ? 376.150 314.455 453.222 1.00 107.29 ? 79  TYR A CZ  1 
ATOM 1923 O OH  . TYR C 3 79  ? 376.372 314.338 451.875 1.00 107.29 ? 79  TYR A OH  1 
ATOM 1924 N N   . THR C 3 80  ? 378.212 314.451 459.129 1.00 116.36 ? 80  THR A N   1 
ATOM 1925 C CA  . THR C 3 80  ? 379.507 313.795 459.171 1.00 116.36 ? 80  THR A CA  1 
ATOM 1926 C C   . THR C 3 80  ? 379.319 312.287 459.207 1.00 116.36 ? 80  THR A C   1 
ATOM 1927 O O   . THR C 3 80  ? 378.218 311.785 459.435 1.00 116.36 ? 80  THR A O   1 
ATOM 1928 C CB  . THR C 3 80  ? 380.320 314.259 460.379 1.00 116.36 ? 80  THR A CB  1 
ATOM 1929 O OG1 . THR C 3 80  ? 381.602 313.624 460.363 1.00 116.36 ? 80  THR A OG1 1 
ATOM 1930 C CG2 . THR C 3 80  ? 379.605 313.923 461.657 1.00 116.36 ? 80  THR A CG2 1 
ATOM 1931 N N   . ASN C 3 81  ? 380.409 311.558 458.977 1.00 118.53 ? 81  ASN A N   1 
ATOM 1932 C CA  . ASN C 3 81  ? 380.299 310.115 458.803 1.00 118.53 ? 81  ASN A CA  1 
ATOM 1933 C C   . ASN C 3 81  ? 380.414 309.332 460.103 1.00 118.53 ? 81  ASN A C   1 
ATOM 1934 O O   . ASN C 3 81  ? 379.712 308.329 460.271 1.00 118.53 ? 81  ASN A O   1 
ATOM 1935 C CB  . ASN C 3 81  ? 381.363 309.615 457.825 1.00 118.53 ? 81  ASN A CB  1 
ATOM 1936 C CG  . ASN C 3 81  ? 382.746 310.096 458.178 1.00 118.53 ? 81  ASN A CG  1 
ATOM 1937 O OD1 . ASN C 3 81  ? 382.916 310.922 459.068 1.00 118.53 ? 81  ASN A OD1 1 
ATOM 1938 N ND2 . ASN C 3 81  ? 383.747 309.578 457.482 1.00 118.53 ? 81  ASN A ND2 1 
ATOM 1939 N N   . ASN C 3 82  ? 381.270 309.758 461.026 1.00 128.53 ? 82  ASN A N   1 
ATOM 1940 C CA  . ASN C 3 82  ? 381.608 308.917 462.166 1.00 128.53 ? 82  ASN A CA  1 
ATOM 1941 C C   . ASN C 3 82  ? 380.625 309.018 463.322 1.00 128.53 ? 82  ASN A C   1 
ATOM 1942 O O   . ASN C 3 82  ? 380.633 308.139 464.189 1.00 128.53 ? 82  ASN A O   1 
ATOM 1943 C CB  . ASN C 3 82  ? 383.010 309.264 462.672 1.00 128.53 ? 82  ASN A CB  1 
ATOM 1944 C CG  . ASN C 3 82  ? 383.067 310.620 463.345 1.00 128.53 ? 82  ASN A CG  1 
ATOM 1945 O OD1 . ASN C 3 82  ? 382.370 311.553 462.953 1.00 128.53 ? 82  ASN A OD1 1 
ATOM 1946 N ND2 . ASN C 3 82  ? 383.904 310.735 464.367 1.00 128.53 ? 82  ASN A ND2 1 
ATOM 1947 N N   . SER C 3 83  ? 379.780 310.042 463.363 1.00 131.14 ? 83  SER A N   1 
ATOM 1948 C CA  . SER C 3 83  ? 379.027 310.358 464.570 1.00 131.14 ? 83  SER A CA  1 
ATOM 1949 C C   . SER C 3 83  ? 377.760 309.544 464.796 1.00 131.14 ? 83  SER A C   1 
ATOM 1950 O O   . SER C 3 83  ? 376.947 309.939 465.639 1.00 131.14 ? 83  SER A O   1 
ATOM 1951 C CB  . SER C 3 83  ? 378.651 311.841 464.586 1.00 131.14 ? 83  SER A CB  1 
ATOM 1952 O OG  . SER C 3 83  ? 377.417 312.058 463.925 1.00 131.14 ? 83  SER A OG  1 
ATOM 1953 N N   . LYS C 3 84  ? 377.526 308.488 464.010 1.00 132.70 ? 84  LYS A N   1 
ATOM 1954 C CA  . LYS C 3 84  ? 376.446 307.486 464.061 1.00 132.70 ? 84  LYS A CA  1 
ATOM 1955 C C   . LYS C 3 84  ? 375.030 308.061 463.926 1.00 132.70 ? 84  LYS A C   1 
ATOM 1956 O O   . LYS C 3 84  ? 374.056 307.301 463.973 1.00 132.70 ? 84  LYS A O   1 
ATOM 1957 C CB  . LYS C 3 84  ? 376.544 306.525 465.272 1.00 132.70 ? 84  LYS A CB  1 
ATOM 1958 C CG  . LYS C 3 84  ? 376.437 307.045 466.724 1.00 132.70 ? 84  LYS A CG  1 
ATOM 1959 C CD  . LYS C 3 84  ? 376.482 305.958 467.792 1.00 132.70 ? 84  LYS A CD  1 
ATOM 1960 C CE  . LYS C 3 84  ? 376.569 306.563 469.183 1.00 132.70 ? 84  LYS A CE  1 
ATOM 1961 N NZ  . LYS C 3 84  ? 375.390 307.415 469.496 1.00 132.70 ? 84  LYS A NZ  1 
ATOM 1962 N N   . LYS C 3 85  ? 374.890 309.373 463.739 1.00 129.74 ? 85  LYS A N   1 
ATOM 1963 C CA  . LYS C 3 85  ? 373.629 309.993 463.363 1.00 129.74 ? 85  LYS A CA  1 
ATOM 1964 C C   . LYS C 3 85  ? 373.809 311.133 462.369 1.00 129.74 ? 85  LYS A C   1 
ATOM 1965 O O   . LYS C 3 85  ? 373.003 312.071 462.371 1.00 129.74 ? 85  LYS A O   1 
ATOM 1966 C CB  . LYS C 3 85  ? 372.943 310.502 464.630 1.00 129.74 ? 85  LYS A CB  1 
ATOM 1967 C CG  . LYS C 3 85  ? 373.850 311.320 465.518 1.00 129.74 ? 85  LYS A CG  1 
ATOM 1968 C CD  . LYS C 3 85  ? 373.091 311.910 466.684 1.00 129.74 ? 85  LYS A CD  1 
ATOM 1969 C CE  . LYS C 3 85  ? 374.034 312.611 467.643 1.00 129.74 ? 85  LYS A CE  1 
ATOM 1970 N NZ  . LYS C 3 85  ? 373.304 313.232 468.780 1.00 129.74 ? 85  LYS A NZ  1 
ATOM 1971 N N   . GLY C 3 86  ? 374.853 311.095 461.547 1.00 113.72 ? 86  GLY A N   1 
ATOM 1972 C CA  . GLY C 3 86  ? 375.075 312.121 460.556 1.00 113.72 ? 86  GLY A CA  1 
ATOM 1973 C C   . GLY C 3 86  ? 374.510 311.754 459.203 1.00 113.72 ? 86  GLY A C   1 
ATOM 1974 O O   . GLY C 3 86  ? 375.139 311.026 458.431 1.00 113.72 ? 86  GLY A O   1 
ATOM 1975 N N   . PHE C 3 87  ? 373.312 312.253 458.920 1.00 107.12 ? 87  PHE A N   1 
ATOM 1976 C CA  . PHE C 3 87  ? 372.696 312.175 457.606 1.00 107.12 ? 87  PHE A CA  1 
ATOM 1977 C C   . PHE C 3 87  ? 371.664 313.290 457.525 1.00 107.12 ? 87  PHE A C   1 
ATOM 1978 O O   . PHE C 3 87  ? 371.085 313.697 458.534 1.00 107.12 ? 87  PHE A O   1 
ATOM 1979 C CB  . PHE C 3 87  ? 372.083 310.794 457.346 1.00 107.12 ? 87  PHE A CB  1 
ATOM 1980 C CG  . PHE C 3 87  ? 370.816 310.527 458.099 1.00 107.12 ? 87  PHE A CG  1 
ATOM 1981 C CD1 . PHE C 3 87  ? 370.851 310.165 459.430 1.00 107.12 ? 87  PHE A CD1 1 
ATOM 1982 C CD2 . PHE C 3 87  ? 369.592 310.603 457.465 1.00 107.12 ? 87  PHE A CD2 1 
ATOM 1983 C CE1 . PHE C 3 87  ? 369.692 309.909 460.118 1.00 107.12 ? 87  PHE A CE1 1 
ATOM 1984 C CE2 . PHE C 3 87  ? 368.431 310.350 458.150 1.00 107.12 ? 87  PHE A CE2 1 
ATOM 1985 C CZ  . PHE C 3 87  ? 368.482 310.002 459.476 1.00 107.12 ? 87  PHE A CZ  1 
ATOM 1986 N N   . ALA C 3 88  ? 371.430 313.786 456.320 1.00 108.59 ? 88  ALA A N   1 
ATOM 1987 C CA  . ALA C 3 88  ? 370.594 314.958 456.130 1.00 108.59 ? 88  ALA A CA  1 
ATOM 1988 C C   . ALA C 3 88  ? 369.159 314.539 455.855 1.00 108.59 ? 88  ALA A C   1 
ATOM 1989 O O   . ALA C 3 88  ? 368.853 313.361 455.675 1.00 108.59 ? 88  ALA A O   1 
ATOM 1990 C CB  . ALA C 3 88  ? 371.127 315.830 454.991 1.00 108.59 ? 88  ALA A CB  1 
ATOM 1991 N N   . GLU C 3 89  ? 368.278 315.533 455.823 1.00 110.72 ? 89  GLU A N   1 
ATOM 1992 C CA  . GLU C 3 89  ? 366.847 315.299 455.725 1.00 110.72 ? 89  GLU A CA  1 
ATOM 1993 C C   . GLU C 3 89  ? 366.186 316.587 455.270 1.00 110.72 ? 89  GLU A C   1 
ATOM 1994 O O   . GLU C 3 89  ? 366.469 317.651 455.822 1.00 110.72 ? 89  GLU A O   1 
ATOM 1995 C CB  . GLU C 3 89  ? 366.269 314.877 457.076 1.00 110.72 ? 89  GLU A CB  1 
ATOM 1996 C CG  . GLU C 3 89  ? 364.800 314.532 457.050 1.00 110.72 ? 89  GLU A CG  1 
ATOM 1997 C CD  . GLU C 3 89  ? 364.406 313.608 458.182 1.00 110.72 ? 89  GLU A CD  1 
ATOM 1998 O OE1 . GLU C 3 89  ? 363.504 313.979 458.962 1.00 110.72 ? 89  GLU A OE1 1 
ATOM 1999 O OE2 . GLU C 3 89  ? 365.013 312.527 458.319 1.00 110.72 ? 89  GLU A OE2 1 
ATOM 2000 N N   . TRP C 3 90  ? 365.301 316.492 454.284 1.00 106.38 ? 90  TRP A N   1 
ATOM 2001 C CA  . TRP C 3 90  ? 364.550 317.664 453.843 1.00 106.38 ? 90  TRP A CA  1 
ATOM 2002 C C   . TRP C 3 90  ? 363.230 317.207 453.250 1.00 106.38 ? 90  TRP A C   1 
ATOM 2003 O O   . TRP C 3 90  ? 363.220 316.481 452.254 1.00 106.38 ? 90  TRP A O   1 
ATOM 2004 C CB  . TRP C 3 90  ? 365.335 318.480 452.826 1.00 106.38 ? 90  TRP A CB  1 
ATOM 2005 C CG  . TRP C 3 90  ? 364.645 319.746 452.471 1.00 106.38 ? 90  TRP A CG  1 
ATOM 2006 C CD1 . TRP C 3 90  ? 364.186 320.687 453.332 1.00 106.38 ? 90  TRP A CD1 1 
ATOM 2007 C CD2 . TRP C 3 90  ? 364.318 320.208 451.160 1.00 106.38 ? 90  TRP A CD2 1 
ATOM 2008 N NE1 . TRP C 3 90  ? 363.598 321.713 452.643 1.00 106.38 ? 90  TRP A NE1 1 
ATOM 2009 C CE2 . TRP C 3 90  ? 363.667 321.441 451.305 1.00 106.38 ? 90  TRP A CE2 1 
ATOM 2010 C CE3 . TRP C 3 90  ? 364.516 319.700 449.879 1.00 106.38 ? 90  TRP A CE3 1 
ATOM 2011 C CZ2 . TRP C 3 90  ? 363.213 322.174 450.221 1.00 106.38 ? 90  TRP A CZ2 1 
ATOM 2012 C CZ3 . TRP C 3 90  ? 364.065 320.429 448.805 1.00 106.38 ? 90  TRP A CZ3 1 
ATOM 2013 C CH2 . TRP C 3 90  ? 363.419 321.651 448.982 1.00 106.38 ? 90  TRP A CH2 1 
ATOM 2014 N N   . VAL C 3 91  ? 362.125 317.639 453.851 1.00 105.55 ? 91  VAL A N   1 
ATOM 2015 C CA  . VAL C 3 91  ? 360.813 317.416 453.258 1.00 105.55 ? 91  VAL A CA  1 
ATOM 2016 C C   . VAL C 3 91  ? 360.605 318.449 452.164 1.00 105.55 ? 91  VAL A C   1 
ATOM 2017 O O   . VAL C 3 91  ? 360.691 319.656 452.412 1.00 105.55 ? 91  VAL A O   1 
ATOM 2018 C CB  . VAL C 3 91  ? 359.710 317.503 454.313 1.00 105.55 ? 91  VAL A CB  1 
ATOM 2019 C CG1 . VAL C 3 91  ? 358.419 316.956 453.754 1.00 105.55 ? 91  VAL A CG1 1 
ATOM 2020 C CG2 . VAL C 3 91  ? 360.119 316.748 455.553 1.00 105.55 ? 91  VAL A CG2 1 
ATOM 2021 N N   . ILE C 3 92  ? 360.336 317.981 450.948 1.00 105.35 ? 92  ILE A N   1 
ATOM 2022 C CA  . ILE C 3 92  ? 360.274 318.879 449.802 1.00 105.35 ? 92  ILE A CA  1 
ATOM 2023 C C   . ILE C 3 92  ? 358.974 319.666 449.856 1.00 105.35 ? 92  ILE A C   1 
ATOM 2024 O O   . ILE C 3 92  ? 357.881 319.093 449.797 1.00 105.35 ? 92  ILE A O   1 
ATOM 2025 C CB  . ILE C 3 92  ? 360.408 318.104 448.488 1.00 105.35 ? 92  ILE A CB  1 
ATOM 2026 C CG1 . ILE C 3 92  ? 361.825 317.567 448.349 1.00 105.35 ? 92  ILE A CG1 1 
ATOM 2027 C CG2 . ILE C 3 92  ? 360.088 318.998 447.317 1.00 105.35 ? 92  ILE A CG2 1 
ATOM 2028 C CD1 . ILE C 3 92  ? 362.060 316.815 447.083 1.00 105.35 ? 92  ILE A CD1 1 
ATOM 2029 N N   . ASN C 3 93  ? 359.089 320.983 449.993 1.00 110.15 ? 93  ASN A N   1 
ATOM 2030 C CA  . ASN C 3 93  ? 357.928 321.853 450.024 1.00 110.15 ? 93  ASN A CA  1 
ATOM 2031 C C   . ASN C 3 93  ? 358.287 323.170 449.355 1.00 110.15 ? 93  ASN A C   1 
ATOM 2032 O O   . ASN C 3 93  ? 359.414 323.375 448.901 1.00 110.15 ? 93  ASN A O   1 
ATOM 2033 C CB  . ASN C 3 93  ? 357.435 322.077 451.455 1.00 110.15 ? 93  ASN A CB  1 
ATOM 2034 C CG  . ASN C 3 93  ? 358.547 322.458 452.406 1.00 110.15 ? 93  ASN A CG  1 
ATOM 2035 O OD1 . ASN C 3 93  ? 359.705 322.577 452.016 1.00 110.15 ? 93  ASN A OD1 1 
ATOM 2036 N ND2 . ASN C 3 93  ? 358.196 322.653 453.669 1.00 110.15 ? 93  ASN A ND2 1 
ATOM 2037 N N   . THR C 3 94  ? 357.315 324.072 449.317 1.00 111.18 ? 94  THR A N   1 
ATOM 2038 C CA  . THR C 3 94  ? 357.486 325.376 448.706 1.00 111.18 ? 94  THR A CA  1 
ATOM 2039 C C   . THR C 3 94  ? 357.637 326.510 449.706 1.00 111.18 ? 94  THR A C   1 
ATOM 2040 O O   . THR C 3 94  ? 358.025 327.610 449.309 1.00 111.18 ? 94  THR A O   1 
ATOM 2041 C CB  . THR C 3 94  ? 356.299 325.685 447.793 1.00 111.18 ? 94  THR A CB  1 
ATOM 2042 O OG1 . THR C 3 94  ? 356.451 327.002 447.268 1.00 111.18 ? 94  THR A OG1 1 
ATOM 2043 C CG2 . THR C 3 94  ? 355.005 325.606 448.569 1.00 111.18 ? 94  THR A CG2 1 
ATOM 2044 N N   . ARG C 3 95  ? 357.349 326.277 450.984 1.00 112.37 ? 95  ARG A N   1 
ATOM 2045 C CA  . ARG C 3 95  ? 357.320 327.336 451.982 1.00 112.37 ? 95  ARG A CA  1 
ATOM 2046 C C   . ARG C 3 95  ? 358.610 327.430 452.781 1.00 112.37 ? 95  ARG A C   1 
ATOM 2047 O O   . ARG C 3 95  ? 358.575 327.793 453.961 1.00 112.37 ? 95  ARG A O   1 
ATOM 2048 C CB  . ARG C 3 95  ? 356.132 327.127 452.916 1.00 112.37 ? 95  ARG A CB  1 
ATOM 2049 C CG  . ARG C 3 95  ? 354.878 326.670 452.207 1.00 112.37 ? 95  ARG A CG  1 
ATOM 2050 C CD  . ARG C 3 95  ? 353.695 326.646 453.148 1.00 112.37 ? 95  ARG A CD  1 
ATOM 2051 N NE  . ARG C 3 95  ? 352.428 326.665 452.429 1.00 112.37 ? 95  ARG A NE  1 
ATOM 2052 C CZ  . ARG C 3 95  ? 351.237 326.675 453.016 1.00 112.37 ? 95  ARG A CZ  1 
ATOM 2053 N NH1 . ARG C 3 95  ? 351.147 326.666 454.338 1.00 112.37 ? 95  ARG A NH1 1 
ATOM 2054 N NH2 . ARG C 3 95  ? 350.135 326.693 452.283 1.00 112.37 ? 95  ARG A NH2 1 
ATOM 2055 N N   . GLN C 3 96  ? 359.752 327.117 452.175 1.00 111.52 ? 96  GLN A N   1 
ATOM 2056 C CA  . GLN C 3 96  ? 360.996 327.095 452.934 1.00 111.52 ? 96  GLN A CA  1 
ATOM 2057 C C   . GLN C 3 96  ? 361.621 328.480 453.020 1.00 111.52 ? 96  GLN A C   1 
ATOM 2058 O O   . GLN C 3 96  ? 361.800 329.025 454.113 1.00 111.52 ? 96  GLN A O   1 
ATOM 2059 C CB  . GLN C 3 96  ? 361.975 326.105 452.305 1.00 111.52 ? 96  GLN A CB  1 
ATOM 2060 C CG  . GLN C 3 96  ? 363.187 325.830 453.159 1.00 111.52 ? 96  GLN A CG  1 
ATOM 2061 C CD  . GLN C 3 96  ? 362.863 324.974 454.356 1.00 111.52 ? 96  GLN A CD  1 
ATOM 2062 O OE1 . GLN C 3 96  ? 363.400 325.177 455.441 1.00 111.52 ? 96  GLN A OE1 1 
ATOM 2063 N NE2 . GLN C 3 96  ? 361.980 324.005 454.166 1.00 111.52 ? 96  GLN A NE2 1 
ATOM 2064 N N   . VAL C 3 97  ? 361.952 329.061 451.888 1.00 110.59 ? 97  VAL A N   1 
ATOM 2065 C CA  . VAL C 3 97  ? 362.604 330.362 451.850 1.00 110.59 ? 97  VAL A CA  1 
ATOM 2066 C C   . VAL C 3 97  ? 361.536 331.424 451.617 1.00 110.59 ? 97  VAL A C   1 
ATOM 2067 O O   . VAL C 3 97  ? 360.567 331.200 450.884 1.00 110.59 ? 97  VAL A O   1 
ATOM 2068 C CB  . VAL C 3 97  ? 363.712 330.373 450.774 1.00 110.59 ? 97  VAL A CB  1 
ATOM 2069 C CG1 . VAL C 3 97  ? 363.172 329.971 449.414 1.00 110.59 ? 97  VAL A CG1 1 
ATOM 2070 C CG2 . VAL C 3 97  ? 364.443 331.705 450.712 1.00 110.59 ? 97  VAL A CG2 1 
ATOM 2071 N N   . ALA C 3 98  ? 361.681 332.568 452.288 1.00 111.52 ? 98  ALA A N   1 
ATOM 2072 C CA  . ALA C 3 98  ? 360.648 333.594 452.301 1.00 111.52 ? 98  ALA A CA  1 
ATOM 2073 C C   . ALA C 3 98  ? 360.469 334.299 450.966 1.00 111.52 ? 98  ALA A C   1 
ATOM 2074 O O   . ALA C 3 98  ? 359.401 334.867 450.732 1.00 111.52 ? 98  ALA A O   1 
ATOM 2075 C CB  . ALA C 3 98  ? 360.956 334.633 453.377 1.00 111.52 ? 98  ALA A CB  1 
ATOM 2076 N N   . GLN C 3 99  ? 361.463 334.278 450.087 1.00 110.50 ? 99  GLN A N   1 
ATOM 2077 C CA  . GLN C 3 99  ? 361.331 334.967 448.813 1.00 110.50 ? 99  GLN A CA  1 
ATOM 2078 C C   . GLN C 3 99  ? 360.606 334.152 447.760 1.00 110.50 ? 99  GLN A C   1 
ATOM 2079 O O   . GLN C 3 99  ? 359.746 334.695 447.064 1.00 110.50 ? 99  GLN A O   1 
ATOM 2080 C CB  . GLN C 3 99  ? 362.704 335.364 448.271 1.00 110.50 ? 99  GLN A CB  1 
ATOM 2081 C CG  . GLN C 3 99  ? 363.225 336.667 448.835 1.00 110.50 ? 99  GLN A CG  1 
ATOM 2082 C CD  . GLN C 3 99  ? 362.756 337.877 448.052 1.00 110.50 ? 99  GLN A CD  1 
ATOM 2083 O OE1 . GLN C 3 99  ? 361.851 337.789 447.224 1.00 110.50 ? 99  GLN A OE1 1 
ATOM 2084 N NE2 . GLN C 3 99  ? 363.376 339.018 448.310 1.00 110.50 ? 99  GLN A NE2 1 
ATOM 2085 N N   . LEU C 3 100 ? 360.927 332.869 447.622 1.00 106.91 ? 100 LEU A N   1 
ATOM 2086 C CA  . LEU C 3 100 ? 360.221 332.015 446.678 1.00 106.91 ? 100 LEU A CA  1 
ATOM 2087 C C   . LEU C 3 100 ? 358.800 331.721 447.122 1.00 106.91 ? 100 LEU A C   1 
ATOM 2088 O O   . LEU C 3 100 ? 357.941 331.437 446.281 1.00 106.91 ? 100 LEU A O   1 
ATOM 2089 C CB  . LEU C 3 100 ? 360.975 330.701 446.485 1.00 106.91 ? 100 LEU A CB  1 
ATOM 2090 C CG  . LEU C 3 100 ? 360.602 329.885 445.251 1.00 106.91 ? 100 LEU A CG  1 
ATOM 2091 C CD1 . LEU C 3 100 ? 361.156 330.533 443.999 1.00 106.91 ? 100 LEU A CD1 1 
ATOM 2092 C CD2 . LEU C 3 100 ? 361.086 328.462 445.394 1.00 106.91 ? 100 LEU A CD2 1 
ATOM 2093 N N   . ARG C 3 101 ? 358.534 331.788 448.426 1.00 107.99 ? 101 ARG A N   1 
ATOM 2094 C CA  . ARG C 3 101 ? 357.170 331.627 448.905 1.00 107.99 ? 101 ARG A CA  1 
ATOM 2095 C C   . ARG C 3 101 ? 356.286 332.775 448.450 1.00 107.99 ? 101 ARG A C   1 
ATOM 2096 O O   . ARG C 3 101 ? 355.114 332.561 448.134 1.00 107.99 ? 101 ARG A O   1 
ATOM 2097 C CB  . ARG C 3 101 ? 357.160 331.520 450.425 1.00 107.99 ? 101 ARG A CB  1 
ATOM 2098 C CG  . ARG C 3 101 ? 355.846 331.066 450.996 1.00 107.99 ? 101 ARG A CG  1 
ATOM 2099 C CD  . ARG C 3 101 ? 355.955 330.834 452.483 1.00 107.99 ? 101 ARG A CD  1 
ATOM 2100 N NE  . ARG C 3 101 ? 354.643 330.690 453.099 1.00 107.99 ? 101 ARG A NE  1 
ATOM 2101 C CZ  . ARG C 3 101 ? 354.438 330.651 454.408 1.00 107.99 ? 101 ARG A CZ  1 
ATOM 2102 N NH1 . ARG C 3 101 ? 355.462 330.750 455.240 1.00 107.99 ? 101 ARG A NH1 1 
ATOM 2103 N NH2 . ARG C 3 101 ? 353.212 330.521 454.885 1.00 107.99 ? 101 ARG A NH2 1 
ATOM 2104 N N   . ARG C 3 102 ? 356.834 333.986 448.374 1.00 105.41 ? 102 ARG A N   1 
ATOM 2105 C CA  . ARG C 3 102 ? 356.032 335.124 447.945 1.00 105.41 ? 102 ARG A CA  1 
ATOM 2106 C C   . ARG C 3 102 ? 355.812 335.121 446.443 1.00 105.41 ? 102 ARG A C   1 
ATOM 2107 O O   . ARG C 3 102 ? 354.788 335.621 445.971 1.00 105.41 ? 102 ARG A O   1 
ATOM 2108 C CB  . ARG C 3 102 ? 356.699 336.424 448.373 1.00 105.41 ? 102 ARG A CB  1 
ATOM 2109 C CG  . ARG C 3 102 ? 355.793 337.629 448.355 1.00 105.41 ? 102 ARG A CG  1 
ATOM 2110 C CD  . ARG C 3 102 ? 356.596 338.880 448.602 1.00 105.41 ? 102 ARG A CD  1 
ATOM 2111 N NE  . ARG C 3 102 ? 355.766 339.991 449.042 1.00 105.41 ? 102 ARG A NE  1 
ATOM 2112 C CZ  . ARG C 3 102 ? 355.327 340.953 448.243 1.00 105.41 ? 102 ARG A CZ  1 
ATOM 2113 N NH1 . ARG C 3 102 ? 355.638 340.942 446.957 1.00 105.41 ? 102 ARG A NH1 1 
ATOM 2114 N NH2 . ARG C 3 102 ? 354.580 341.926 448.735 1.00 105.41 ? 102 ARG A NH2 1 
ATOM 2115 N N   . LYS C 3 103 ? 356.747 334.566 445.676 1.00 104.55 ? 103 LYS A N   1 
ATOM 2116 C CA  . LYS C 3 103 ? 356.579 334.542 444.229 1.00 104.55 ? 103 LYS A CA  1 
ATOM 2117 C C   . LYS C 3 103 ? 355.626 333.445 443.782 1.00 104.55 ? 103 LYS A C   1 
ATOM 2118 O O   . LYS C 3 103 ? 355.125 333.491 442.656 1.00 104.55 ? 103 LYS A O   1 
ATOM 2119 C CB  . LYS C 3 103 ? 357.930 334.373 443.539 1.00 104.55 ? 103 LYS A CB  1 
ATOM 2120 C CG  . LYS C 3 103 ? 358.722 335.657 443.423 1.00 104.55 ? 103 LYS A CG  1 
ATOM 2121 C CD  . LYS C 3 103 ? 360.096 335.408 442.837 1.00 104.55 ? 103 LYS A CD  1 
ATOM 2122 C CE  . LYS C 3 103 ? 360.002 334.737 441.481 1.00 104.55 ? 103 LYS A CE  1 
ATOM 2123 N NZ  . LYS C 3 103 ? 361.338 334.340 440.963 1.00 104.55 ? 103 LYS A NZ  1 
ATOM 2124 N N   . LEU C 3 104 ? 355.370 332.457 444.631 1.00 103.70 ? 104 LEU A N   1 
ATOM 2125 C CA  . LEU C 3 104 ? 354.403 331.424 444.300 1.00 103.70 ? 104 LEU A CA  1 
ATOM 2126 C C   . LEU C 3 104 ? 353.046 331.661 444.941 1.00 103.70 ? 104 LEU A C   1 
ATOM 2127 O O   . LEU C 3 104 ? 352.054 331.085 444.487 1.00 103.70 ? 104 LEU A O   1 
ATOM 2128 C CB  . LEU C 3 104 ? 354.945 330.053 444.704 1.00 103.70 ? 104 LEU A CB  1 
ATOM 2129 C CG  . LEU C 3 104 ? 356.226 329.641 443.981 1.00 103.70 ? 104 LEU A CG  1 
ATOM 2130 C CD1 . LEU C 3 104 ? 356.586 328.219 444.278 1.00 103.70 ? 104 LEU A CD1 1 
ATOM 2131 C CD2 . LEU C 3 104 ? 356.064 329.805 442.499 1.00 103.70 ? 104 LEU A CD2 1 
ATOM 2132 N N   . GLU C 3 105 ? 352.969 332.505 445.964 1.00 111.27 ? 105 GLU A N   1 
ATOM 2133 C CA  . GLU C 3 105 ? 351.701 332.866 446.577 1.00 111.27 ? 105 GLU A CA  1 
ATOM 2134 C C   . GLU C 3 105 ? 350.937 333.920 445.790 1.00 111.27 ? 105 GLU A C   1 
ATOM 2135 O O   . GLU C 3 105 ? 349.885 334.369 446.251 1.00 111.27 ? 105 GLU A O   1 
ATOM 2136 C CB  . GLU C 3 105 ? 351.925 333.365 448.005 1.00 111.27 ? 105 GLU A CB  1 
ATOM 2137 C CG  . GLU C 3 105 ? 351.951 332.266 449.049 1.00 111.27 ? 105 GLU A CG  1 
ATOM 2138 C CD  . GLU C 3 105 ? 351.966 332.811 450.465 1.00 111.27 ? 105 GLU A CD  1 
ATOM 2139 O OE1 . GLU C 3 105 ? 352.238 334.017 450.637 1.00 111.27 ? 105 GLU A OE1 1 
ATOM 2140 O OE2 . GLU C 3 105 ? 351.703 332.034 451.408 1.00 111.27 ? 105 GLU A OE2 1 
ATOM 2141 N N   . LEU C 3 106 ? 351.440 334.346 444.632 1.00 104.16 ? 106 LEU A N   1 
ATOM 2142 C CA  . LEU C 3 106 ? 350.630 335.164 443.745 1.00 104.16 ? 106 LEU A CA  1 
ATOM 2143 C C   . LEU C 3 106 ? 349.567 334.340 443.044 1.00 104.16 ? 106 LEU A C   1 
ATOM 2144 O O   . LEU C 3 106 ? 348.548 334.891 442.623 1.00 104.16 ? 106 LEU A O   1 
ATOM 2145 C CB  . LEU C 3 106 ? 351.504 335.859 442.703 1.00 104.16 ? 106 LEU A CB  1 
ATOM 2146 C CG  . LEU C 3 106 ? 352.569 336.832 443.193 1.00 104.16 ? 106 LEU A CG  1 
ATOM 2147 C CD1 . LEU C 3 106 ? 353.134 337.611 442.034 1.00 104.16 ? 106 LEU A CD1 1 
ATOM 2148 C CD2 . LEU C 3 106 ? 351.979 337.771 444.200 1.00 104.16 ? 106 LEU A CD2 1 
ATOM 2149 N N   . PHE C 3 107 ? 349.785 333.039 442.908 1.00 102.87 ? 107 PHE A N   1 
ATOM 2150 C CA  . PHE C 3 107 ? 348.835 332.144 442.276 1.00 102.87 ? 107 PHE A CA  1 
ATOM 2151 C C   . PHE C 3 107 ? 348.343 331.132 443.296 1.00 102.87 ? 107 PHE A C   1 
ATOM 2152 O O   . PHE C 3 107 ? 348.983 330.891 444.321 1.00 102.87 ? 107 PHE A O   1 
ATOM 2153 C CB  . PHE C 3 107 ? 349.462 331.418 441.086 1.00 102.87 ? 107 PHE A CB  1 
ATOM 2154 C CG  . PHE C 3 107 ? 350.287 332.301 440.214 1.00 102.87 ? 107 PHE A CG  1 
ATOM 2155 C CD1 . PHE C 3 107 ? 349.687 333.188 439.349 1.00 102.87 ? 107 PHE A CD1 1 
ATOM 2156 C CD2 . PHE C 3 107 ? 351.663 332.245 440.260 1.00 102.87 ? 107 PHE A CD2 1 
ATOM 2157 C CE1 . PHE C 3 107 ? 350.445 334.001 438.545 1.00 102.87 ? 107 PHE A CE1 1 
ATOM 2158 C CE2 . PHE C 3 107 ? 352.426 333.058 439.459 1.00 102.87 ? 107 PHE A CE2 1 
ATOM 2159 C CZ  . PHE C 3 107 ? 351.816 333.936 438.602 1.00 102.87 ? 107 PHE A CZ  1 
ATOM 2160 N N   . THR C 3 108 ? 347.194 330.536 443.000 1.00 100.72 ? 108 THR A N   1 
ATOM 2161 C CA  . THR C 3 108 ? 346.590 329.550 443.880 1.00 100.72 ? 108 THR A CA  1 
ATOM 2162 C C   . THR C 3 108 ? 346.907 328.120 443.465 1.00 100.72 ? 108 THR A C   1 
ATOM 2163 O O   . THR C 3 108 ? 347.334 327.320 444.302 1.00 100.72 ? 108 THR A O   1 
ATOM 2164 C CB  . THR C 3 108 ? 345.076 329.762 443.927 1.00 100.72 ? 108 THR A CB  1 
ATOM 2165 O OG1 . THR C 3 108 ? 344.797 331.031 444.524 1.00 100.72 ? 108 THR A OG1 1 
ATOM 2166 C CG2 . THR C 3 108 ? 344.393 328.686 444.737 1.00 100.72 ? 108 THR A CG2 1 
ATOM 2167 N N   . TYR C 3 109 ? 346.747 327.784 442.189 1.00 103.24 ? 109 TYR A N   1 
ATOM 2168 C CA  . TYR C 3 109 ? 347.012 326.439 441.696 1.00 103.24 ? 109 TYR A CA  1 
ATOM 2169 C C   . TYR C 3 109 ? 348.161 326.479 440.702 1.00 103.24 ? 109 TYR A C   1 
ATOM 2170 O O   . TYR C 3 109 ? 348.079 327.168 439.682 1.00 103.24 ? 109 TYR A O   1 
ATOM 2171 C CB  . TYR C 3 109 ? 345.767 325.835 441.051 1.00 103.24 ? 109 TYR A CB  1 
ATOM 2172 C CG  . TYR C 3 109 ? 344.589 325.799 441.980 1.00 103.24 ? 109 TYR A CG  1 
ATOM 2173 C CD1 . TYR C 3 109 ? 344.669 325.152 443.198 1.00 103.24 ? 109 TYR A CD1 1 
ATOM 2174 C CD2 . TYR C 3 109 ? 343.400 326.415 441.644 1.00 103.24 ? 109 TYR A CD2 1 
ATOM 2175 C CE1 . TYR C 3 109 ? 343.598 325.119 444.055 1.00 103.24 ? 109 TYR A CE1 1 
ATOM 2176 C CE2 . TYR C 3 109 ? 342.324 326.392 442.496 1.00 103.24 ? 109 TYR A CE2 1 
ATOM 2177 C CZ  . TYR C 3 109 ? 342.430 325.741 443.699 1.00 103.24 ? 109 TYR A CZ  1 
ATOM 2178 O OH  . TYR C 3 109 ? 341.361 325.707 444.554 1.00 103.24 ? 109 TYR A OH  1 
ATOM 2179 N N   . LEU C 3 110 ? 349.221 325.739 441.000 1.00 100.72 ? 110 LEU A N   1 
ATOM 2180 C CA  . LEU C 3 110 ? 350.376 325.601 440.131 1.00 100.72 ? 110 LEU A CA  1 
ATOM 2181 C C   . LEU C 3 110 ? 350.533 324.151 439.702 1.00 100.72 ? 110 LEU A C   1 
ATOM 2182 O O   . LEU C 3 110 ? 349.996 323.235 440.326 1.00 100.72 ? 110 LEU A O   1 
ATOM 2183 C CB  . LEU C 3 110 ? 351.648 326.065 440.836 1.00 100.72 ? 110 LEU A CB  1 
ATOM 2184 C CG  . LEU C 3 110 ? 351.736 327.550 441.138 1.00 100.72 ? 110 LEU A CG  1 
ATOM 2185 C CD1 . LEU C 3 110 ? 352.855 327.799 442.106 1.00 100.72 ? 110 LEU A CD1 1 
ATOM 2186 C CD2 . LEU C 3 110 ? 351.972 328.308 439.860 1.00 100.72 ? 110 LEU A CD2 1 
ATOM 2187 N N   . ARG C 3 111 ? 351.287 323.948 438.627 1.00 101.87 ? 111 ARG A N   1 
ATOM 2188 C CA  . ARG C 3 111 ? 351.555 322.602 438.132 1.00 101.87 ? 111 ARG A CA  1 
ATOM 2189 C C   . ARG C 3 111 ? 352.896 322.630 437.419 1.00 101.87 ? 111 ARG A C   1 
ATOM 2190 O O   . ARG C 3 111 ? 352.999 323.192 436.329 1.00 101.87 ? 111 ARG A O   1 
ATOM 2191 C CB  . ARG C 3 111 ? 350.449 322.133 437.199 1.00 101.87 ? 111 ARG A CB  1 
ATOM 2192 C CG  . ARG C 3 111 ? 350.633 320.726 436.697 1.00 101.87 ? 111 ARG A CG  1 
ATOM 2193 C CD  . ARG C 3 111 ? 349.668 320.416 435.580 1.00 101.87 ? 111 ARG A CD  1 
ATOM 2194 N NE  . ARG C 3 111 ? 349.991 319.157 434.924 1.00 101.87 ? 111 ARG A NE  1 
ATOM 2195 C CZ  . ARG C 3 111 ? 349.156 318.130 434.831 1.00 101.87 ? 111 ARG A CZ  1 
ATOM 2196 N NH1 . ARG C 3 111 ? 347.944 318.213 435.351 1.00 101.87 ? 111 ARG A NH1 1 
ATOM 2197 N NH2 . ARG C 3 111 ? 349.533 317.022 434.214 1.00 101.87 ? 111 ARG A NH2 1 
ATOM 2198 N N   . PHE C 3 112 ? 353.917 322.027 438.023 1.00 98.54  ? 112 PHE A N   1 
ATOM 2199 C CA  . PHE C 3 112 ? 355.244 322.071 437.433 1.00 98.54  ? 112 PHE A CA  1 
ATOM 2200 C C   . PHE C 3 112 ? 355.963 320.751 437.647 1.00 98.54  ? 112 PHE A C   1 
ATOM 2201 O O   . PHE C 3 112 ? 355.688 320.015 438.594 1.00 98.54  ? 112 PHE A O   1 
ATOM 2202 C CB  . PHE C 3 112 ? 356.083 323.218 438.008 1.00 98.54  ? 112 PHE A CB  1 
ATOM 2203 C CG  . PHE C 3 112 ? 356.053 323.324 439.511 1.00 98.54  ? 112 PHE A CG  1 
ATOM 2204 C CD1 . PHE C 3 112 ? 356.896 322.561 440.299 1.00 98.54  ? 112 PHE A CD1 1 
ATOM 2205 C CD2 . PHE C 3 112 ? 355.217 324.227 440.132 1.00 98.54  ? 112 PHE A CD2 1 
ATOM 2206 C CE1 . PHE C 3 112 ? 356.880 322.673 441.670 1.00 98.54  ? 112 PHE A CE1 1 
ATOM 2207 C CE2 . PHE C 3 112 ? 355.200 324.343 441.505 1.00 98.54  ? 112 PHE A CE2 1 
ATOM 2208 C CZ  . PHE C 3 112 ? 356.033 323.565 442.272 1.00 98.54  ? 112 PHE A CZ  1 
ATOM 2209 N N   . ASP C 3 113 ? 356.905 320.472 436.752 1.00 106.67 ? 113 ASP A N   1 
ATOM 2210 C CA  . ASP C 3 113 ? 357.922 319.465 436.996 1.00 106.67 ? 113 ASP A CA  1 
ATOM 2211 C C   . ASP C 3 113 ? 358.988 320.049 437.914 1.00 106.67 ? 113 ASP A C   1 
ATOM 2212 O O   . ASP C 3 113 ? 358.970 321.232 438.254 1.00 106.67 ? 113 ASP A O   1 
ATOM 2213 C CB  . ASP C 3 113 ? 358.535 318.993 435.683 1.00 106.67 ? 113 ASP A CB  1 
ATOM 2214 C CG  . ASP C 3 113 ? 357.498 318.506 434.702 1.00 106.67 ? 113 ASP A CG  1 
ATOM 2215 O OD1 . ASP C 3 113 ? 356.647 319.318 434.289 1.00 106.67 ? 113 ASP A OD1 1 
ATOM 2216 O OD2 . ASP C 3 113 ? 357.527 317.309 434.347 1.00 106.67 ? 113 ASP A OD2 1 
ATOM 2217 N N   . LEU C 3 114 ? 359.950 319.228 438.312 1.00 99.38  ? 114 LEU A N   1 
ATOM 2218 C CA  . LEU C 3 114 ? 360.969 319.700 439.230 1.00 99.38  ? 114 LEU A CA  1 
ATOM 2219 C C   . LEU C 3 114 ? 362.331 319.217 438.771 1.00 99.38  ? 114 LEU A C   1 
ATOM 2220 O O   . LEU C 3 114 ? 362.461 318.137 438.194 1.00 99.38  ? 114 LEU A O   1 
ATOM 2221 C CB  . LEU C 3 114 ? 360.696 319.231 440.656 1.00 99.38  ? 114 LEU A CB  1 
ATOM 2222 C CG  . LEU C 3 114 ? 361.122 320.222 441.729 1.00 99.38  ? 114 LEU A CG  1 
ATOM 2223 C CD1 . LEU C 3 114 ? 360.454 321.538 441.458 1.00 99.38  ? 114 LEU A CD1 1 
ATOM 2224 C CD2 . LEU C 3 114 ? 360.738 319.719 443.094 1.00 99.38  ? 114 LEU A CD2 1 
ATOM 2225 N N   . GLU C 3 115 ? 363.346 320.036 439.030 1.00 105.19 ? 115 GLU A N   1 
ATOM 2226 C CA  . GLU C 3 115 ? 364.714 319.713 438.646 1.00 105.19 ? 115 GLU A CA  1 
ATOM 2227 C C   . GLU C 3 115 ? 365.638 320.218 439.739 1.00 105.19 ? 115 GLU A C   1 
ATOM 2228 O O   . GLU C 3 115 ? 365.694 321.424 439.988 1.00 105.19 ? 115 GLU A O   1 
ATOM 2229 C CB  . GLU C 3 115 ? 365.068 320.343 437.303 1.00 105.19 ? 115 GLU A CB  1 
ATOM 2230 C CG  . GLU C 3 115 ? 366.541 320.295 436.967 1.00 105.19 ? 115 GLU A CG  1 
ATOM 2231 C CD  . GLU C 3 115 ? 366.805 320.583 435.506 1.00 105.19 ? 115 GLU A CD  1 
ATOM 2232 O OE1 . GLU C 3 115 ? 366.055 320.071 434.654 1.00 105.19 ? 115 GLU A OE1 1 
ATOM 2233 O OE2 . GLU C 3 115 ? 367.759 321.327 435.206 1.00 105.19 ? 115 GLU A OE2 1 
ATOM 2234 N N   . LEU C 3 116 ? 366.359 319.305 440.380 1.00 99.48  ? 116 LEU A N   1 
ATOM 2235 C CA  . LEU C 3 116 ? 367.150 319.622 441.558 1.00 99.48  ? 116 LEU A CA  1 
ATOM 2236 C C   . LEU C 3 116 ? 368.624 319.397 441.274 1.00 99.48  ? 116 LEU A C   1 
ATOM 2237 O O   . LEU C 3 116 ? 368.988 318.481 440.536 1.00 99.48  ? 116 LEU A O   1 
ATOM 2238 C CB  . LEU C 3 116 ? 366.728 318.776 442.756 1.00 99.48  ? 116 LEU A CB  1 
ATOM 2239 C CG  . LEU C 3 116 ? 365.421 319.184 443.428 1.00 99.48  ? 116 LEU A CG  1 
ATOM 2240 C CD1 . LEU C 3 116 ? 364.266 318.426 442.837 1.00 99.48  ? 116 LEU A CD1 1 
ATOM 2241 C CD2 . LEU C 3 116 ? 365.483 318.967 444.911 1.00 99.48  ? 116 LEU A CD2 1 
ATOM 2242 N N   . THR C 3 117 ? 369.467 320.234 441.870 1.00 96.17  ? 117 THR A N   1 
ATOM 2243 C CA  . THR C 3 117 ? 370.909 320.130 441.726 1.00 96.17  ? 117 THR A CA  1 
ATOM 2244 C C   . THR C 3 117 ? 371.553 320.314 443.087 1.00 96.17  ? 117 THR A C   1 
ATOM 2245 O O   . THR C 3 117 ? 371.178 321.217 443.836 1.00 96.17  ? 117 THR A O   1 
ATOM 2246 C CB  . THR C 3 117 ? 371.447 321.172 440.756 1.00 96.17  ? 117 THR A CB  1 
ATOM 2247 O OG1 . THR C 3 117 ? 370.573 321.265 439.629 1.00 96.17  ? 117 THR A OG1 1 
ATOM 2248 C CG2 . THR C 3 117 ? 372.820 320.786 440.281 1.00 96.17  ? 117 THR A CG2 1 
ATOM 2249 N N   . PHE C 3 118 ? 372.520 319.462 443.401 1.00 95.91  ? 118 PHE A N   1 
ATOM 2250 C CA  . PHE C 3 118 ? 373.150 319.429 444.711 1.00 95.91  ? 118 PHE A CA  1 
ATOM 2251 C C   . PHE C 3 118 ? 374.620 319.787 444.574 1.00 95.91  ? 118 PHE A C   1 
ATOM 2252 O O   . PHE C 3 118 ? 375.330 319.192 443.761 1.00 95.91  ? 118 PHE A O   1 
ATOM 2253 C CB  . PHE C 3 118 ? 373.020 318.045 445.340 1.00 95.91  ? 118 PHE A CB  1 
ATOM 2254 C CG  . PHE C 3 118 ? 371.649 317.454 445.237 1.00 95.91  ? 118 PHE A CG  1 
ATOM 2255 C CD1 . PHE C 3 118 ? 370.658 317.812 446.122 1.00 95.91  ? 118 PHE A CD1 1 
ATOM 2256 C CD2 . PHE C 3 118 ? 371.361 316.521 444.262 1.00 95.91  ? 118 PHE A CD2 1 
ATOM 2257 C CE1 . PHE C 3 118 ? 369.402 317.256 446.028 1.00 95.91  ? 118 PHE A CE1 1 
ATOM 2258 C CE2 . PHE C 3 118 ? 370.108 315.967 444.163 1.00 95.91  ? 118 PHE A CE2 1 
ATOM 2259 C CZ  . PHE C 3 118 ? 369.130 316.334 445.045 1.00 95.91  ? 118 PHE A CZ  1 
ATOM 2260 N N   . VAL C 3 119 ? 375.081 320.735 445.374 1.00 92.92  ? 119 VAL A N   1 
ATOM 2261 C CA  . VAL C 3 119 ? 376.481 321.136 445.384 1.00 92.92  ? 119 VAL A CA  1 
ATOM 2262 C C   . VAL C 3 119 ? 377.068 320.654 446.703 1.00 92.92  ? 119 VAL A C   1 
ATOM 2263 O O   . VAL C 3 119 ? 376.942 321.324 447.732 1.00 92.92  ? 119 VAL A O   1 
ATOM 2264 C CB  . VAL C 3 119 ? 376.645 322.646 445.216 1.00 92.92  ? 119 VAL A CB  1 
ATOM 2265 C CG1 . VAL C 3 119 ? 378.101 322.992 445.065 1.00 92.92  ? 119 VAL A CG1 1 
ATOM 2266 C CG2 . VAL C 3 119 ? 375.865 323.120 444.018 1.00 92.92  ? 119 VAL A CG2 1 
ATOM 2267 N N   . ILE C 3 120 ? 377.716 319.496 446.681 1.00 98.42  ? 120 ILE A N   1 
ATOM 2268 C CA  . ILE C 3 120 ? 378.239 318.865 447.884 1.00 98.42  ? 120 ILE A CA  1 
ATOM 2269 C C   . ILE C 3 120 ? 379.733 319.123 447.965 1.00 98.42  ? 120 ILE A C   1 
ATOM 2270 O O   . ILE C 3 120 ? 380.460 318.920 446.987 1.00 98.42  ? 120 ILE A O   1 
ATOM 2271 C CB  . ILE C 3 120 ? 377.948 317.357 447.895 1.00 98.42  ? 120 ILE A CB  1 
ATOM 2272 C CG1 . ILE C 3 120 ? 376.503 317.096 447.492 1.00 98.42  ? 120 ILE A CG1 1 
ATOM 2273 C CG2 . ILE C 3 120 ? 378.205 316.784 449.269 1.00 98.42  ? 120 ILE A CG2 1 
ATOM 2274 C CD1 . ILE C 3 120 ? 376.132 315.644 447.508 1.00 98.42  ? 120 ILE A CD1 1 
ATOM 2275 N N   . THR C 3 121 ? 380.192 319.560 449.131 1.00 107.89 ? 121 THR A N   1 
ATOM 2276 C CA  . THR C 3 121 ? 381.603 319.810 449.366 1.00 107.89 ? 121 THR A CA  1 
ATOM 2277 C C   . THR C 3 121 ? 381.993 319.215 450.708 1.00 107.89 ? 121 THR A C   1 
ATOM 2278 O O   . THR C 3 121 ? 381.135 318.882 451.525 1.00 107.89 ? 121 THR A O   1 
ATOM 2279 C CB  . THR C 3 121 ? 381.921 321.301 449.342 1.00 107.89 ? 121 THR A CB  1 
ATOM 2280 O OG1 . THR C 3 121 ? 383.283 321.506 449.738 1.00 107.89 ? 121 THR A OG1 1 
ATOM 2281 C CG2 . THR C 3 121 ? 381.001 322.044 450.283 1.00 107.89 ? 121 THR A CG2 1 
ATOM 2282 N N   . SER C 3 122 ? 383.294 319.088 450.928 1.00 113.00 ? 122 SER A N   1 
ATOM 2283 C CA  . SER C 3 122 ? 383.833 318.382 452.078 1.00 113.00 ? 122 SER A CA  1 
ATOM 2284 C C   . SER C 3 122 ? 384.661 319.312 452.951 1.00 113.00 ? 122 SER A C   1 
ATOM 2285 O O   . SER C 3 122 ? 385.027 320.418 452.555 1.00 113.00 ? 122 SER A O   1 
ATOM 2286 C CB  . SER C 3 122 ? 384.687 317.198 451.623 1.00 113.00 ? 122 SER A CB  1 
ATOM 2287 O OG  . SER C 3 122 ? 385.320 316.584 452.726 1.00 113.00 ? 122 SER A OG  1 
ATOM 2288 N N   . ALA C 3 123 ? 384.970 318.828 454.152 1.00 116.48 ? 123 ALA A N   1 
ATOM 2289 C CA  . ALA C 3 123 ? 385.780 319.570 455.108 1.00 116.48 ? 123 ALA A CA  1 
ATOM 2290 C C   . ALA C 3 123 ? 386.396 318.581 456.082 1.00 116.48 ? 123 ALA A C   1 
ATOM 2291 O O   . ALA C 3 123 ? 385.690 317.725 456.618 1.00 116.48 ? 123 ALA A O   1 
ATOM 2292 C CB  . ALA C 3 123 ? 384.943 320.604 455.861 1.00 116.48 ? 123 ALA A CB  1 
ATOM 2293 N N   . GLN C 3 124 ? 387.698 318.696 456.310 1.00 124.05 ? 124 GLN A N   1 
ATOM 2294 C CA  . GLN C 3 124 ? 388.395 317.753 457.173 1.00 124.05 ? 124 GLN A CA  1 
ATOM 2295 C C   . GLN C 3 124 ? 388.271 318.183 458.628 1.00 124.05 ? 124 GLN A C   1 
ATOM 2296 O O   . GLN C 3 124 ? 388.694 319.282 458.997 1.00 124.05 ? 124 GLN A O   1 
ATOM 2297 C CB  . GLN C 3 124 ? 389.861 317.645 456.773 1.00 124.05 ? 124 GLN A CB  1 
ATOM 2298 C CG  . GLN C 3 124 ? 390.688 316.852 457.759 1.00 124.05 ? 124 GLN A CG  1 
ATOM 2299 C CD  . GLN C 3 124 ? 392.142 316.771 457.368 1.00 124.05 ? 124 GLN A CD  1 
ATOM 2300 O OE1 . GLN C 3 124 ? 392.507 317.051 456.228 1.00 124.05 ? 124 GLN A OE1 1 
ATOM 2301 N NE2 . GLN C 3 124 ? 392.986 316.386 458.314 1.00 124.05 ? 124 GLN A NE2 1 
ATOM 2302 N N   . GLN C 3 125 ? 387.699 317.314 459.453 1.00 129.86 ? 125 GLN A N   1 
ATOM 2303 C CA  . GLN C 3 125 ? 387.622 317.554 460.880 1.00 129.86 ? 125 GLN A CA  1 
ATOM 2304 C C   . GLN C 3 125 ? 388.960 317.209 461.533 1.00 129.86 ? 125 GLN A C   1 
ATOM 2305 O O   . GLN C 3 125 ? 389.752 316.456 460.966 1.00 129.86 ? 125 GLN A O   1 
ATOM 2306 C CB  . GLN C 3 125 ? 386.492 316.722 461.477 1.00 129.86 ? 125 GLN A CB  1 
ATOM 2307 C CG  . GLN C 3 125 ? 385.126 317.210 461.072 1.00 129.86 ? 125 GLN A CG  1 
ATOM 2308 C CD  . GLN C 3 125 ? 384.988 318.700 461.240 1.00 129.86 ? 125 GLN A CD  1 
ATOM 2309 O OE1 . GLN C 3 125 ? 384.895 319.439 460.264 1.00 129.86 ? 125 GLN A OE1 1 
ATOM 2310 N NE2 . GLN C 3 125 ? 384.981 319.154 462.483 1.00 129.86 ? 125 GLN A NE2 1 
ATOM 2311 N N   . PRO C 3 126 ? 389.253 317.772 462.724 1.00 138.17 ? 126 PRO A N   1 
ATOM 2312 C CA  . PRO C 3 126 ? 390.523 317.444 463.389 1.00 138.17 ? 126 PRO A CA  1 
ATOM 2313 C C   . PRO C 3 126 ? 390.605 316.009 463.879 1.00 138.17 ? 126 PRO A C   1 
ATOM 2314 O O   . PRO C 3 126 ? 389.893 315.615 464.807 1.00 138.17 ? 126 PRO A O   1 
ATOM 2315 C CB  . PRO C 3 126 ? 390.569 318.429 464.564 1.00 138.17 ? 126 PRO A CB  1 
ATOM 2316 C CG  . PRO C 3 126 ? 389.164 318.848 464.767 1.00 138.17 ? 126 PRO A CG  1 
ATOM 2317 C CD  . PRO C 3 126 ? 388.587 318.901 463.396 1.00 138.17 ? 126 PRO A CD  1 
ATOM 2318 N N   . SER C 3 127 ? 391.482 315.224 463.261 1.00 151.43 ? 127 SER A N   1 
ATOM 2319 C CA  . SER C 3 127 ? 391.703 313.841 463.652 1.00 151.43 ? 127 SER A CA  1 
ATOM 2320 C C   . SER C 3 127 ? 392.732 313.796 464.777 1.00 151.43 ? 127 SER A C   1 
ATOM 2321 O O   . SER C 3 127 ? 393.155 314.828 465.302 1.00 151.43 ? 127 SER A O   1 
ATOM 2322 C CB  . SER C 3 127 ? 392.142 313.009 462.451 1.00 151.43 ? 127 SER A CB  1 
ATOM 2323 O OG  . SER C 3 127 ? 392.728 311.790 462.870 1.00 151.43 ? 127 SER A OG  1 
ATOM 2324 N N   . THR C 3 128 ? 393.153 312.592 465.164 1.00 158.69 ? 128 THR A N   1 
ATOM 2325 C CA  . THR C 3 128 ? 394.078 312.483 466.290 1.00 158.69 ? 128 THR A CA  1 
ATOM 2326 C C   . THR C 3 128 ? 395.533 312.726 465.878 1.00 158.69 ? 128 THR A C   1 
ATOM 2327 O O   . THR C 3 128 ? 396.128 313.728 466.289 1.00 158.69 ? 128 THR A O   1 
ATOM 2328 C CB  . THR C 3 128 ? 393.861 311.148 467.029 1.00 158.69 ? 128 THR A CB  1 
ATOM 2329 O OG1 . THR C 3 128 ? 394.801 311.011 468.103 1.00 158.69 ? 128 THR A OG1 1 
ATOM 2330 C CG2 . THR C 3 128 ? 393.806 309.893 466.119 1.00 158.69 ? 128 THR A CG2 1 
ATOM 2331 N N   . ALA C 3 129 ? 396.100 311.878 465.018 1.00 159.12 ? 129 ALA A N   1 
ATOM 2332 C CA  . ALA C 3 129 ? 397.524 311.912 464.679 1.00 159.12 ? 129 ALA A CA  1 
ATOM 2333 C C   . ALA C 3 129 ? 397.787 310.956 463.520 1.00 159.12 ? 129 ALA A C   1 
ATOM 2334 O O   . ALA C 3 129 ? 396.861 310.369 462.947 1.00 159.12 ? 129 ALA A O   1 
ATOM 2335 C CB  . ALA C 3 129 ? 398.406 311.533 465.874 1.00 159.12 ? 129 ALA A CB  1 
ATOM 2336 N N   . SER C 3 130 ? 399.076 310.800 463.202 1.00 160.27 ? 130 SER A N   1 
ATOM 2337 C CA  . SER C 3 130 ? 399.663 309.718 462.397 1.00 160.27 ? 130 SER A CA  1 
ATOM 2338 C C   . SER C 3 130 ? 399.132 309.683 460.962 1.00 160.27 ? 130 SER A C   1 
ATOM 2339 O O   . SER C 3 130 ? 398.570 308.682 460.511 1.00 160.27 ? 130 SER A O   1 
ATOM 2340 C CB  . SER C 3 130 ? 399.502 308.341 463.067 1.00 160.27 ? 130 SER A CB  1 
ATOM 2341 O OG  . SER C 3 130 ? 398.166 307.997 463.402 1.00 160.27 ? 130 SER A OG  1 
ATOM 2342 N N   . SER C 3 131 ? 399.344 310.797 460.255 1.00 156.39 ? 131 SER A N   1 
ATOM 2343 C CA  . SER C 3 131 ? 399.417 310.861 458.790 1.00 156.39 ? 131 SER A CA  1 
ATOM 2344 C C   . SER C 3 131 ? 398.133 310.377 458.108 1.00 156.39 ? 131 SER A C   1 
ATOM 2345 O O   . SER C 3 131 ? 398.101 309.344 457.443 1.00 156.39 ? 131 SER A O   1 
ATOM 2346 C CB  . SER C 3 131 ? 400.619 310.061 458.290 1.00 156.39 ? 131 SER A CB  1 
ATOM 2347 O OG  . SER C 3 131 ? 400.273 308.698 458.139 1.00 156.39 ? 131 SER A OG  1 
ATOM 2348 N N   . VAL C 3 132 ? 397.065 311.144 458.318 1.00 148.00 ? 132 VAL A N   1 
ATOM 2349 C CA  . VAL C 3 132 ? 395.780 310.815 457.716 1.00 148.00 ? 132 VAL A CA  1 
ATOM 2350 C C   . VAL C 3 132 ? 395.846 311.047 456.210 1.00 148.00 ? 132 VAL A C   1 
ATOM 2351 O O   . VAL C 3 132 ? 396.428 312.030 455.735 1.00 148.00 ? 132 VAL A O   1 
ATOM 2352 C CB  . VAL C 3 132 ? 394.653 311.614 458.397 1.00 148.00 ? 132 VAL A CB  1 
ATOM 2353 C CG1 . VAL C 3 132 ? 394.906 313.111 458.345 1.00 148.00 ? 132 VAL A CG1 1 
ATOM 2354 C CG2 . VAL C 3 132 ? 393.294 311.277 457.801 1.00 148.00 ? 132 VAL A CG2 1 
ATOM 2355 N N   . ASP C 3 133 ? 395.317 310.094 455.446 1.00 145.00 ? 133 ASP A N   1 
ATOM 2356 C CA  . ASP C 3 133 ? 395.249 310.198 453.992 1.00 145.00 ? 133 ASP A CA  1 
ATOM 2357 C C   . ASP C 3 133 ? 394.002 309.429 453.585 1.00 145.00 ? 133 ASP A C   1 
ATOM 2358 O O   . ASP C 3 133 ? 393.870 308.245 453.905 1.00 145.00 ? 133 ASP A O   1 
ATOM 2359 C CB  . ASP C 3 133 ? 396.507 309.625 453.332 1.00 145.00 ? 133 ASP A CB  1 
ATOM 2360 C CG  . ASP C 3 133 ? 396.585 309.896 451.824 1.00 145.00 ? 133 ASP A CG  1 
ATOM 2361 O OD1 . ASP C 3 133 ? 395.575 310.235 451.175 1.00 145.00 ? 133 ASP A OD1 1 
ATOM 2362 O OD2 . ASP C 3 133 ? 397.697 309.759 451.275 1.00 145.00 ? 133 ASP A OD2 1 
ATOM 2363 N N   . ALA C 3 134 ? 393.098 310.094 452.873 1.00 130.31 ? 134 ALA A N   1 
ATOM 2364 C CA  . ALA C 3 134 ? 391.828 309.483 452.533 1.00 130.31 ? 134 ALA A CA  1 
ATOM 2365 C C   . ALA C 3 134 ? 391.649 309.414 451.024 1.00 130.31 ? 134 ALA A C   1 
ATOM 2366 O O   . ALA C 3 134 ? 392.142 310.279 450.297 1.00 130.31 ? 134 ALA A O   1 
ATOM 2367 C CB  . ALA C 3 134 ? 390.662 310.268 453.144 1.00 130.31 ? 134 ALA A CB  1 
ATOM 2368 N N   . PRO C 3 135 ? 390.951 308.394 450.524 1.00 121.09 ? 135 PRO A N   1 
ATOM 2369 C CA  . PRO C 3 135 ? 390.608 308.365 449.096 1.00 121.09 ? 135 PRO A CA  1 
ATOM 2370 C C   . PRO C 3 135 ? 389.463 309.306 448.766 1.00 121.09 ? 135 PRO A C   1 
ATOM 2371 O O   . PRO C 3 135 ? 388.963 310.010 449.647 1.00 121.09 ? 135 PRO A O   1 
ATOM 2372 C CB  . PRO C 3 135 ? 390.215 306.901 448.859 1.00 121.09 ? 135 PRO A CB  1 
ATOM 2373 C CG  . PRO C 3 135 ? 390.761 306.155 450.030 1.00 121.09 ? 135 PRO A CG  1 
ATOM 2374 C CD  . PRO C 3 135 ? 390.671 307.106 451.170 1.00 121.09 ? 135 PRO A CD  1 
ATOM 2375 N N   . VAL C 3 136 ? 389.041 309.329 447.500 1.00 116.82 ? 136 VAL A N   1 
ATOM 2376 C CA  . VAL C 3 136 ? 387.954 310.210 447.099 1.00 116.82 ? 136 VAL A CA  1 
ATOM 2377 C C   . VAL C 3 136 ? 386.640 309.703 447.680 1.00 116.82 ? 136 VAL A C   1 
ATOM 2378 O O   . VAL C 3 136 ? 386.382 308.495 447.746 1.00 116.82 ? 136 VAL A O   1 
ATOM 2379 C CB  . VAL C 3 136 ? 387.887 310.334 445.566 1.00 116.82 ? 136 VAL A CB  1 
ATOM 2380 C CG1 . VAL C 3 136 ? 389.049 311.158 445.061 1.00 116.82 ? 136 VAL A CG1 1 
ATOM 2381 C CG2 . VAL C 3 136 ? 387.917 308.971 444.915 1.00 116.82 ? 136 VAL A CG2 1 
ATOM 2382 N N   . GLN C 3 137 ? 385.815 310.635 448.138 1.00 109.33 ? 137 GLN A N   1 
ATOM 2383 C CA  . GLN C 3 137 ? 384.592 310.287 448.841 1.00 109.33 ? 137 GLN A CA  1 
ATOM 2384 C C   . GLN C 3 137 ? 383.446 310.087 447.862 1.00 109.33 ? 137 GLN A C   1 
ATOM 2385 O O   . GLN C 3 137 ? 383.507 310.494 446.702 1.00 109.33 ? 137 GLN A O   1 
ATOM 2386 C CB  . GLN C 3 137 ? 384.233 311.364 449.855 1.00 109.33 ? 137 GLN A CB  1 
ATOM 2387 C CG  . GLN C 3 137 ? 385.252 311.510 450.954 1.00 109.33 ? 137 GLN A CG  1 
ATOM 2388 C CD  . GLN C 3 137 ? 385.292 310.306 451.858 1.00 109.33 ? 137 GLN A CD  1 
ATOM 2389 O OE1 . GLN C 3 137 ? 386.360 309.812 452.206 1.00 109.33 ? 137 GLN A OE1 1 
ATOM 2390 N NE2 . GLN C 3 137 ? 384.122 309.824 452.246 1.00 109.33 ? 137 GLN A NE2 1 
ATOM 2391 N N   . THR C 3 138 ? 382.390 309.446 448.349 1.00 104.80 ? 138 THR A N   1 
ATOM 2392 C CA  . THR C 3 138 ? 381.239 309.113 447.528 1.00 104.80 ? 138 THR A CA  1 
ATOM 2393 C C   . THR C 3 138 ? 379.985 309.310 448.365 1.00 104.80 ? 138 THR A C   1 
ATOM 2394 O O   . THR C 3 138 ? 379.938 308.885 449.520 1.00 104.80 ? 138 THR A O   1 
ATOM 2395 C CB  . THR C 3 138 ? 381.339 307.672 447.016 1.00 104.80 ? 138 THR A CB  1 
ATOM 2396 O OG1 . THR C 3 138 ? 382.535 307.528 446.245 1.00 104.80 ? 138 THR A OG1 1 
ATOM 2397 C CG2 . THR C 3 138 ? 380.169 307.332 446.121 1.00 104.80 ? 138 THR A CG2 1 
ATOM 2398 N N   . HIS C 3 139 ? 378.981 309.968 447.794 1.00 99.45  ? 139 HIS A N   1 
ATOM 2399 C CA  . HIS C 3 139 ? 377.767 310.304 448.519 1.00 99.45  ? 139 HIS A CA  1 
ATOM 2400 C C   . HIS C 3 139 ? 376.567 309.653 447.849 1.00 99.45  ? 139 HIS A C   1 
ATOM 2401 O O   . HIS C 3 139 ? 376.592 309.362 446.654 1.00 99.45  ? 139 HIS A O   1 
ATOM 2402 C CB  . HIS C 3 139 ? 377.556 311.815 448.584 1.00 99.45  ? 139 HIS A CB  1 
ATOM 2403 C CG  . HIS C 3 139 ? 378.732 312.575 449.111 1.00 99.45  ? 139 HIS A CG  1 
ATOM 2404 N ND1 . HIS C 3 139 ? 378.741 313.154 450.360 1.00 99.45  ? 139 HIS A ND1 1 
ATOM 2405 C CD2 . HIS C 3 139 ? 379.925 312.879 448.549 1.00 99.45  ? 139 HIS A CD2 1 
ATOM 2406 C CE1 . HIS C 3 139 ? 379.895 313.765 450.553 1.00 99.45  ? 139 HIS A CE1 1 
ATOM 2407 N NE2 . HIS C 3 139 ? 380.632 313.613 449.469 1.00 99.45  ? 139 HIS A NE2 1 
ATOM 2408 N N   . GLN C 3 140 ? 375.512 309.430 448.630 1.00 95.65  ? 140 GLN A N   1 
ATOM 2409 C CA  . GLN C 3 140 ? 374.275 308.841 448.135 1.00 95.65  ? 140 GLN A CA  1 
ATOM 2410 C C   . GLN C 3 140 ? 373.112 309.739 448.513 1.00 95.65  ? 140 GLN A C   1 
ATOM 2411 O O   . GLN C 3 140 ? 372.924 310.041 449.693 1.00 95.65  ? 140 GLN A O   1 
ATOM 2412 C CB  . GLN C 3 140 ? 374.049 307.445 448.707 1.00 95.65  ? 140 GLN A CB  1 
ATOM 2413 C CG  . GLN C 3 140 ? 372.633 306.945 448.535 1.00 95.65  ? 140 GLN A CG  1 
ATOM 2414 C CD  . GLN C 3 140 ? 372.397 305.614 449.198 1.00 95.65  ? 140 GLN A CD  1 
ATOM 2415 O OE1 . GLN C 3 140 ? 373.052 305.269 450.177 1.00 95.65  ? 140 GLN A OE1 1 
ATOM 2416 N NE2 . GLN C 3 140 ? 371.455 304.855 448.668 1.00 95.65  ? 140 GLN A NE2 1 
ATOM 2417 N N   . ILE C 3 141 ? 372.330 310.153 447.522 1.00 93.83  ? 141 ILE A N   1 
ATOM 2418 C CA  . ILE C 3 141 ? 371.232 311.094 447.714 1.00 93.83  ? 141 ILE A CA  1 
ATOM 2419 C C   . ILE C 3 141 ? 369.941 310.368 447.371 1.00 93.83  ? 141 ILE A C   1 
ATOM 2420 O O   . ILE C 3 141 ? 369.585 310.249 446.196 1.00 93.83  ? 141 ILE A O   1 
ATOM 2421 C CB  . ILE C 3 141 ? 371.398 312.349 446.860 1.00 93.83  ? 141 ILE A CB  1 
ATOM 2422 C CG1 . ILE C 3 141 ? 372.777 312.958 447.089 1.00 93.83  ? 141 ILE A CG1 1 
ATOM 2423 C CG2 . ILE C 3 141 ? 370.317 313.340 447.184 1.00 93.83  ? 141 ILE A CG2 1 
ATOM 2424 C CD1 . ILE C 3 141 ? 373.222 313.853 445.983 1.00 93.83  ? 141 ILE A CD1 1 
ATOM 2425 N N   . MET C 3 142 ? 369.223 309.898 448.385 1.00 99.80  ? 142 MET A N   1 
ATOM 2426 C CA  . MET C 3 142 ? 368.056 309.046 448.189 1.00 99.80  ? 142 MET A CA  1 
ATOM 2427 C C   . MET C 3 142 ? 366.790 309.885 448.154 1.00 99.80  ? 142 MET A C   1 
ATOM 2428 O O   . MET C 3 142 ? 366.627 310.804 448.960 1.00 99.80  ? 142 MET A O   1 
ATOM 2429 C CB  . MET C 3 142 ? 367.953 307.994 449.292 1.00 99.80  ? 142 MET A CB  1 
ATOM 2430 C CG  . MET C 3 142 ? 366.964 306.898 448.993 1.00 99.80  ? 142 MET A CG  1 
ATOM 2431 S SD  . MET C 3 142 ? 367.025 305.550 450.173 1.00 99.80  ? 142 MET A SD  1 
ATOM 2432 C CE  . MET C 3 142 ? 365.896 306.147 451.415 1.00 99.80  ? 142 MET A CE  1 
ATOM 2433 N N   . TYR C 3 143 ? 365.899 309.564 447.225 1.00 101.95 ? 143 TYR A N   1 
ATOM 2434 C CA  . TYR C 3 143 ? 364.619 310.242 447.090 1.00 101.95 ? 143 TYR A CA  1 
ATOM 2435 C C   . TYR C 3 143 ? 363.507 309.275 447.462 1.00 101.95 ? 143 TYR A C   1 
ATOM 2436 O O   . TYR C 3 143 ? 363.398 308.199 446.870 1.00 101.95 ? 143 TYR A O   1 
ATOM 2437 C CB  . TYR C 3 143 ? 364.419 310.752 445.669 1.00 101.95 ? 143 TYR A CB  1 
ATOM 2438 C CG  . TYR C 3 143 ? 363.061 311.351 445.465 1.00 101.95 ? 143 TYR A CG  1 
ATOM 2439 C CD1 . TYR C 3 143 ? 362.691 312.495 446.145 1.00 101.95 ? 143 TYR A CD1 1 
ATOM 2440 C CD2 . TYR C 3 143 ? 362.145 310.773 444.606 1.00 101.95 ? 143 TYR A CD2 1 
ATOM 2441 C CE1 . TYR C 3 143 ? 361.455 313.052 445.976 1.00 101.95 ? 143 TYR A CE1 1 
ATOM 2442 C CE2 . TYR C 3 143 ? 360.900 311.325 444.429 1.00 101.95 ? 143 TYR A CE2 1 
ATOM 2443 C CZ  . TYR C 3 143 ? 360.566 312.465 445.119 1.00 101.95 ? 143 TYR A CZ  1 
ATOM 2444 O OH  . TYR C 3 143 ? 359.335 313.033 444.961 1.00 101.95 ? 143 TYR A OH  1 
ATOM 2445 N N   . VAL C 3 144 ? 362.683 309.658 448.426 1.00 104.36 ? 144 VAL A N   1 
ATOM 2446 C CA  . VAL C 3 144 ? 361.578 308.829 448.898 1.00 104.36 ? 144 VAL A CA  1 
ATOM 2447 C C   . VAL C 3 144 ? 360.286 309.383 448.310 1.00 104.36 ? 144 VAL A C   1 
ATOM 2448 O O   . VAL C 3 144 ? 359.964 310.553 448.558 1.00 104.36 ? 144 VAL A O   1 
ATOM 2449 C CB  . VAL C 3 144 ? 361.512 308.800 450.430 1.00 104.36 ? 144 VAL A CB  1 
ATOM 2450 C CG1 . VAL C 3 144 ? 360.253 308.117 450.885 1.00 104.36 ? 144 VAL A CG1 1 
ATOM 2451 C CG2 . VAL C 3 144 ? 362.709 308.086 450.989 1.00 104.36 ? 144 VAL A CG2 1 
ATOM 2452 N N   . PRO C 3 145 ? 359.530 308.601 447.543 1.00 104.17 ? 145 PRO A N   1 
ATOM 2453 C CA  . PRO C 3 145 ? 358.244 309.067 447.011 1.00 104.17 ? 145 PRO A CA  1 
ATOM 2454 C C   . PRO C 3 145 ? 357.217 309.217 448.121 1.00 104.17 ? 145 PRO A C   1 
ATOM 2455 O O   . PRO C 3 145 ? 357.456 308.760 449.248 1.00 104.17 ? 145 PRO A O   1 
ATOM 2456 C CB  . PRO C 3 145 ? 357.859 307.945 446.032 1.00 104.17 ? 145 PRO A CB  1 
ATOM 2457 C CG  . PRO C 3 145 ? 359.128 307.293 445.697 1.00 104.17 ? 145 PRO A CG  1 
ATOM 2458 C CD  . PRO C 3 145 ? 359.919 307.318 446.951 1.00 104.17 ? 145 PRO A CD  1 
ATOM 2459 N N   . PRO C 3 146 ? 356.078 309.872 447.866 1.00 109.61 ? 146 PRO A N   1 
ATOM 2460 C CA  . PRO C 3 146 ? 355.053 310.004 448.915 1.00 109.61 ? 146 PRO A CA  1 
ATOM 2461 C C   . PRO C 3 146 ? 354.451 308.657 449.285 1.00 109.61 ? 146 PRO A C   1 
ATOM 2462 O O   . PRO C 3 146 ? 353.777 308.018 448.477 1.00 109.61 ? 146 PRO A O   1 
ATOM 2463 C CB  . PRO C 3 146 ? 354.012 310.929 448.277 1.00 109.61 ? 146 PRO A CB  1 
ATOM 2464 C CG  . PRO C 3 146 ? 354.274 310.857 446.826 1.00 109.61 ? 146 PRO A CG  1 
ATOM 2465 C CD  . PRO C 3 146 ? 355.747 310.729 446.716 1.00 109.61 ? 146 PRO A CD  1 
ATOM 2466 N N   . GLY C 3 147 ? 354.706 308.229 450.516 1.00 111.05 ? 147 GLY A N   1 
ATOM 2467 C CA  . GLY C 3 147 ? 354.243 306.939 450.976 1.00 111.05 ? 147 GLY A CA  1 
ATOM 2468 C C   . GLY C 3 147 ? 355.278 305.855 450.782 1.00 111.05 ? 147 GLY A C   1 
ATOM 2469 O O   . GLY C 3 147 ? 354.973 304.784 450.252 1.00 111.05 ? 147 GLY A O   1 
ATOM 2470 N N   . GLY C 3 148 ? 356.508 306.122 451.203 1.00 110.73 ? 148 GLY A N   1 
ATOM 2471 C CA  . GLY C 3 148 ? 357.577 305.164 451.078 1.00 110.73 ? 148 GLY A CA  1 
ATOM 2472 C C   . GLY C 3 148 ? 358.274 304.921 452.399 1.00 110.73 ? 148 GLY A C   1 
ATOM 2473 O O   . GLY C 3 148 ? 357.929 305.516 453.424 1.00 110.73 ? 148 GLY A O   1 
ATOM 2474 N N   . PRO C 3 149 ? 359.263 304.032 452.404 1.00 110.68 ? 149 PRO A N   1 
ATOM 2475 C CA  . PRO C 3 149 ? 360.004 303.761 453.637 1.00 110.68 ? 149 PRO A CA  1 
ATOM 2476 C C   . PRO C 3 149 ? 360.926 304.912 454.003 1.00 110.68 ? 149 PRO A C   1 
ATOM 2477 O O   . PRO C 3 149 ? 361.514 305.577 453.150 1.00 110.68 ? 149 PRO A O   1 
ATOM 2478 C CB  . PRO C 3 149 ? 360.801 302.499 453.301 1.00 110.68 ? 149 PRO A CB  1 
ATOM 2479 C CG  . PRO C 3 149 ? 360.939 302.537 451.830 1.00 110.68 ? 149 PRO A CG  1 
ATOM 2480 C CD  . PRO C 3 149 ? 359.674 303.140 451.310 1.00 110.68 ? 149 PRO A CD  1 
ATOM 2481 N N   . VAL C 3 150 ? 361.041 305.139 455.307 1.00 113.41 ? 150 VAL A N   1 
ATOM 2482 C CA  . VAL C 3 150 ? 361.769 306.276 455.864 1.00 113.41 ? 150 VAL A CA  1 
ATOM 2483 C C   . VAL C 3 150 ? 362.899 305.789 456.763 1.00 113.41 ? 150 VAL A C   1 
ATOM 2484 O O   . VAL C 3 150 ? 362.649 305.029 457.708 1.00 113.41 ? 150 VAL A O   1 
ATOM 2485 C CB  . VAL C 3 150 ? 360.823 307.204 456.640 1.00 113.41 ? 150 VAL A CB  1 
ATOM 2486 C CG1 . VAL C 3 150 ? 361.572 308.387 457.166 1.00 113.41 ? 150 VAL A CG1 1 
ATOM 2487 C CG2 . VAL C 3 150 ? 359.695 307.682 455.747 1.00 113.41 ? 150 VAL A CG2 1 
ATOM 2488 N N   . PRO C 3 151 ? 364.140 306.200 456.523 1.00 110.69 ? 151 PRO A N   1 
ATOM 2489 C CA  . PRO C 3 151 ? 365.241 305.777 457.389 1.00 110.69 ? 151 PRO A CA  1 
ATOM 2490 C C   . PRO C 3 151 ? 365.301 306.595 458.664 1.00 110.69 ? 151 PRO A C   1 
ATOM 2491 O O   . PRO C 3 151 ? 364.853 307.740 458.724 1.00 110.69 ? 151 PRO A O   1 
ATOM 2492 C CB  . PRO C 3 151 ? 366.487 306.027 456.530 1.00 110.69 ? 151 PRO A CB  1 
ATOM 2493 C CG  . PRO C 3 151 ? 365.986 306.509 455.205 1.00 110.69 ? 151 PRO A CG  1 
ATOM 2494 C CD  . PRO C 3 151 ? 364.619 307.033 455.416 1.00 110.69 ? 151 PRO A CD  1 
ATOM 2495 N N   . THR C 3 152 ? 365.867 305.981 459.702 1.00 115.75 ? 152 THR A N   1 
ATOM 2496 C CA  . THR C 3 152 ? 366.096 306.653 460.970 1.00 115.75 ? 152 THR A CA  1 
ATOM 2497 C C   . THR C 3 152 ? 367.543 306.623 461.425 1.00 115.75 ? 152 THR A C   1 
ATOM 2498 O O   . THR C 3 152 ? 367.940 307.492 462.205 1.00 115.75 ? 152 THR A O   1 
ATOM 2499 C CB  . THR C 3 152 ? 365.235 306.035 462.082 1.00 115.75 ? 152 THR A CB  1 
ATOM 2500 O OG1 . THR C 3 152 ? 365.551 304.645 462.211 1.00 115.75 ? 152 THR A OG1 1 
ATOM 2501 C CG2 . THR C 3 152 ? 363.755 306.196 461.784 1.00 115.75 ? 152 THR A CG2 1 
ATOM 2502 N N   . LYS C 3 153 ? 368.332 305.654 460.981 1.00 117.89 ? 153 LYS A N   1 
ATOM 2503 C CA  . LYS C 3 153 ? 369.750 305.590 461.284 1.00 117.89 ? 153 LYS A CA  1 
ATOM 2504 C C   . LYS C 3 153 ? 370.538 305.568 459.984 1.00 117.89 ? 153 LYS A C   1 
ATOM 2505 O O   . LYS C 3 153 ? 369.976 305.456 458.893 1.00 117.89 ? 153 LYS A O   1 
ATOM 2506 C CB  . LYS C 3 153 ? 370.085 304.355 462.125 1.00 117.89 ? 153 LYS A CB  1 
ATOM 2507 C CG  . LYS C 3 153 ? 369.232 304.194 463.363 1.00 117.89 ? 153 LYS A CG  1 
ATOM 2508 C CD  . LYS C 3 153 ? 369.377 302.799 463.937 1.00 117.89 ? 153 LYS A CD  1 
ATOM 2509 C CE  . LYS C 3 153 ? 368.899 301.750 462.953 1.00 117.89 ? 153 LYS A CE  1 
ATOM 2510 N NZ  . LYS C 3 153 ? 368.989 300.378 463.519 1.00 117.89 ? 153 LYS A NZ  1 
ATOM 2511 N N   . VAL C 3 154 ? 371.859 305.676 460.110 1.00 116.20 ? 154 VAL A N   1 
ATOM 2512 C CA  . VAL C 3 154 ? 372.715 305.648 458.932 1.00 116.20 ? 154 VAL A CA  1 
ATOM 2513 C C   . VAL C 3 154 ? 372.756 304.252 458.332 1.00 116.20 ? 154 VAL A C   1 
ATOM 2514 O O   . VAL C 3 154 ? 372.658 304.085 457.113 1.00 116.20 ? 154 VAL A O   1 
ATOM 2515 C CB  . VAL C 3 154 ? 374.118 306.155 459.295 1.00 116.20 ? 154 VAL A CB  1 
ATOM 2516 C CG1 . VAL C 3 154 ? 374.996 306.221 458.065 1.00 116.20 ? 154 VAL A CG1 1 
ATOM 2517 C CG2 . VAL C 3 154 ? 374.021 307.510 459.954 1.00 116.20 ? 154 VAL A CG2 1 
ATOM 2518 N N   . LYS C 3 155 ? 372.876 303.230 459.168 1.00 122.32 ? 155 LYS A N   1 
ATOM 2519 C CA  . LYS C 3 155 ? 372.821 301.843 458.724 1.00 122.32 ? 155 LYS A CA  1 
ATOM 2520 C C   . LYS C 3 155 ? 371.405 301.335 458.957 1.00 122.32 ? 155 LYS A C   1 
ATOM 2521 O O   . LYS C 3 155 ? 371.052 300.952 460.076 1.00 122.32 ? 155 LYS A O   1 
ATOM 2522 C CB  . LYS C 3 155 ? 373.845 300.991 459.465 1.00 122.32 ? 155 LYS A CB  1 
ATOM 2523 C CG  . LYS C 3 155 ? 375.266 301.491 459.319 1.00 122.32 ? 155 LYS A CG  1 
ATOM 2524 C CD  . LYS C 3 155 ? 376.215 300.362 458.966 1.00 122.32 ? 155 LYS A CD  1 
ATOM 2525 C CE  . LYS C 3 155 ? 377.656 300.839 458.960 1.00 122.32 ? 155 LYS A CE  1 
ATOM 2526 N NZ  . LYS C 3 155 ? 378.119 301.173 457.586 1.00 122.32 ? 155 LYS A NZ  1 
ATOM 2527 N N   . ASP C 3 156 ? 370.600 301.328 457.901 1.00 120.10 ? 156 ASP A N   1 
ATOM 2528 C CA  . ASP C 3 156 ? 369.198 300.962 458.019 1.00 120.10 ? 156 ASP A CA  1 
ATOM 2529 C C   . ASP C 3 156 ? 368.789 300.221 456.758 1.00 120.10 ? 156 ASP A C   1 
ATOM 2530 O O   . ASP C 3 156 ? 369.480 300.267 455.739 1.00 120.10 ? 156 ASP A O   1 
ATOM 2531 C CB  . ASP C 3 156 ? 368.323 302.198 458.238 1.00 120.10 ? 156 ASP A CB  1 
ATOM 2532 C CG  . ASP C 3 156 ? 366.989 301.866 458.866 1.00 120.10 ? 156 ASP A CG  1 
ATOM 2533 O OD1 . ASP C 3 156 ? 366.950 301.618 460.087 1.00 120.10 ? 156 ASP A OD1 1 
ATOM 2534 O OD2 . ASP C 3 156 ? 365.978 301.851 458.137 1.00 120.10 ? 156 ASP A OD2 1 
ATOM 2535 N N   . TYR C 3 157 ? 367.653 299.528 456.846 1.00 126.04 ? 157 TYR A N   1 
ATOM 2536 C CA  . TYR C 3 157 ? 367.156 298.757 455.714 1.00 126.04 ? 157 TYR A CA  1 
ATOM 2537 C C   . TYR C 3 157 ? 366.627 299.657 454.605 1.00 126.04 ? 157 TYR A C   1 
ATOM 2538 O O   . TYR C 3 157 ? 366.697 299.291 453.428 1.00 126.04 ? 157 TYR A O   1 
ATOM 2539 C CB  . TYR C 3 157 ? 366.074 297.790 456.195 1.00 126.04 ? 157 TYR A CB  1 
ATOM 2540 C CG  . TYR C 3 157 ? 365.172 297.260 455.108 1.00 126.04 ? 157 TYR A CG  1 
ATOM 2541 C CD1 . TYR C 3 157 ? 365.652 296.369 454.154 1.00 126.04 ? 157 TYR A CD1 1 
ATOM 2542 C CD2 . TYR C 3 157 ? 363.841 297.651 455.032 1.00 126.04 ? 157 TYR A CD2 1 
ATOM 2543 C CE1 . TYR C 3 157 ? 364.832 295.884 453.154 1.00 126.04 ? 157 TYR A CE1 1 
ATOM 2544 C CE2 . TYR C 3 157 ? 363.012 297.170 454.036 1.00 126.04 ? 157 TYR A CE2 1 
ATOM 2545 C CZ  . TYR C 3 157 ? 363.514 296.287 453.101 1.00 126.04 ? 157 TYR A CZ  1 
ATOM 2546 O OH  . TYR C 3 157 ? 362.696 295.802 452.107 1.00 126.04 ? 157 TYR A OH  1 
ATOM 2547 N N   . ALA C 3 158 ? 366.141 300.849 454.952 1.00 111.87 ? 158 ALA A N   1 
ATOM 2548 C CA  . ALA C 3 158 ? 365.477 301.711 453.982 1.00 111.87 ? 158 ALA A CA  1 
ATOM 2549 C C   . ALA C 3 158 ? 366.422 302.287 452.938 1.00 111.87 ? 158 ALA A C   1 
ATOM 2550 O O   . ALA C 3 158 ? 365.954 302.806 451.924 1.00 111.87 ? 158 ALA A O   1 
ATOM 2551 C CB  . ALA C 3 158 ? 364.762 302.849 454.702 1.00 111.87 ? 158 ALA A CB  1 
ATOM 2552 N N   . TRP C 3 159 ? 367.734 302.217 453.157 1.00 106.09 ? 159 TRP A N   1 
ATOM 2553 C CA  . TRP C 3 159 ? 368.665 302.701 452.147 1.00 106.09 ? 159 TRP A CA  1 
ATOM 2554 C C   . TRP C 3 159 ? 368.814 301.701 451.009 1.00 106.09 ? 159 TRP A C   1 
ATOM 2555 O O   . TRP C 3 159 ? 368.991 302.092 449.850 1.00 106.09 ? 159 TRP A O   1 
ATOM 2556 C CB  . TRP C 3 159 ? 370.023 302.982 452.777 1.00 106.09 ? 159 TRP A CB  1 
ATOM 2557 C CG  . TRP C 3 159 ? 369.989 303.995 453.854 1.00 106.09 ? 159 TRP A CG  1 
ATOM 2558 C CD1 . TRP C 3 159 ? 369.948 303.760 455.189 1.00 106.09 ? 159 TRP A CD1 1 
ATOM 2559 C CD2 . TRP C 3 159 ? 370.012 305.412 453.696 1.00 106.09 ? 159 TRP A CD2 1 
ATOM 2560 N NE1 . TRP C 3 159 ? 369.937 304.944 455.876 1.00 106.09 ? 159 TRP A NE1 1 
ATOM 2561 C CE2 . TRP C 3 159 ? 369.975 305.974 454.977 1.00 106.09 ? 159 TRP A CE2 1 
ATOM 2562 C CE3 . TRP C 3 159 ? 370.057 306.259 452.593 1.00 106.09 ? 159 TRP A CE3 1 
ATOM 2563 C CZ2 . TRP C 3 159 ? 369.983 307.338 455.187 1.00 106.09 ? 159 TRP A CZ2 1 
ATOM 2564 C CZ3 . TRP C 3 159 ? 370.064 307.611 452.804 1.00 106.09 ? 159 TRP A CZ3 1 
ATOM 2565 C CH2 . TRP C 3 159 ? 370.030 308.139 454.088 1.00 106.09 ? 159 TRP A CH2 1 
ATOM 2566 N N   . GLN C 3 160 ? 368.747 300.409 451.318 1.00 110.26 ? 160 GLN A N   1 
ATOM 2567 C CA  . GLN C 3 160 ? 368.999 299.353 450.350 1.00 110.26 ? 160 GLN A CA  1 
ATOM 2568 C C   . GLN C 3 160 ? 367.745 298.920 449.603 1.00 110.26 ? 160 GLN A C   1 
ATOM 2569 O O   . GLN C 3 160 ? 367.743 297.843 449.000 1.00 110.26 ? 160 GLN A O   1 
ATOM 2570 C CB  . GLN C 3 160 ? 369.619 298.144 451.049 1.00 110.26 ? 160 GLN A CB  1 
ATOM 2571 C CG  . GLN C 3 160 ? 370.908 298.435 451.792 1.00 110.26 ? 160 GLN A CG  1 
ATOM 2572 C CD  . GLN C 3 160 ? 372.073 298.732 450.868 1.00 110.26 ? 160 GLN A CD  1 
ATOM 2573 O OE1 . GLN C 3 160 ? 372.536 299.869 450.781 1.00 110.26 ? 160 GLN A OE1 1 
ATOM 2574 N NE2 . GLN C 3 160 ? 372.562 297.703 450.181 1.00 110.26 ? 160 GLN A NE2 1 
ATOM 2575 N N   . THR C 3 161 ? 366.685 299.722 449.626 1.00 110.80 ? 161 THR A N   1 
ATOM 2576 C CA  . THR C 3 161 ? 365.430 299.314 449.016 1.00 110.80 ? 161 THR A CA  1 
ATOM 2577 C C   . THR C 3 161 ? 365.480 299.485 447.499 1.00 110.80 ? 161 THR A C   1 
ATOM 2578 O O   . THR C 3 161 ? 366.472 299.939 446.927 1.00 110.80 ? 161 THR A O   1 
ATOM 2579 C CB  . THR C 3 161 ? 364.265 300.102 449.603 1.00 110.80 ? 161 THR A CB  1 
ATOM 2580 O OG1 . THR C 3 161 ? 363.034 299.580 449.098 1.00 110.80 ? 161 THR A OG1 1 
ATOM 2581 C CG2 . THR C 3 161 ? 364.374 301.539 449.213 1.00 110.80 ? 161 THR A CG2 1 
ATOM 2582 N N   . SER C 3 162 ? 364.385 299.109 446.842 1.00 108.58 ? 162 SER A N   1 
ATOM 2583 C CA  . SER C 3 162 ? 364.356 299.031 445.389 1.00 108.58 ? 162 SER A CA  1 
ATOM 2584 C C   . SER C 3 162 ? 363.529 300.117 444.725 1.00 108.58 ? 162 SER A C   1 
ATOM 2585 O O   . SER C 3 162 ? 363.821 300.477 443.581 1.00 108.58 ? 162 SER A O   1 
ATOM 2586 C CB  . SER C 3 162 ? 363.811 297.672 444.944 1.00 108.58 ? 162 SER A CB  1 
ATOM 2587 O OG  . SER C 3 162 ? 363.664 297.631 443.538 1.00 108.58 ? 162 SER A OG  1 
ATOM 2588 N N   . THR C 3 163 ? 362.504 300.635 445.393 1.00 108.18 ? 163 THR A N   1 
ATOM 2589 C CA  . THR C 3 163 ? 361.625 301.598 444.746 1.00 108.18 ? 163 THR A CA  1 
ATOM 2590 C C   . THR C 3 163 ? 362.032 303.039 445.010 1.00 108.18 ? 163 THR A C   1 
ATOM 2591 O O   . THR C 3 163 ? 361.365 303.961 444.531 1.00 108.18 ? 163 THR A O   1 
ATOM 2592 C CB  . THR C 3 163 ? 360.186 301.395 445.204 1.00 108.18 ? 163 THR A CB  1 
ATOM 2593 O OG1 . THR C 3 163 ? 359.339 302.292 444.481 1.00 108.18 ? 163 THR A OG1 1 
ATOM 2594 C CG2 . THR C 3 163 ? 360.068 301.690 446.679 1.00 108.18 ? 163 THR A CG2 1 
ATOM 2595 N N   . ASN C 3 164 ? 363.090 303.259 445.773 1.00 102.68 ? 164 ASN A N   1 
ATOM 2596 C CA  . ASN C 3 164 ? 363.562 304.617 446.009 1.00 102.68 ? 164 ASN A CA  1 
ATOM 2597 C C   . ASN C 3 164 ? 364.714 304.911 445.065 1.00 102.68 ? 164 ASN A C   1 
ATOM 2598 O O   . ASN C 3 164 ? 365.788 304.318 445.222 1.00 102.68 ? 164 ASN A O   1 
ATOM 2599 C CB  . ASN C 3 164 ? 364.020 304.801 447.452 1.00 102.68 ? 164 ASN A CB  1 
ATOM 2600 C CG  . ASN C 3 164 ? 362.894 304.668 448.456 1.00 102.68 ? 164 ASN A CG  1 
ATOM 2601 O OD1 . ASN C 3 164 ? 363.138 304.582 449.656 1.00 102.68 ? 164 ASN A OD1 1 
ATOM 2602 N ND2 . ASN C 3 164 ? 361.662 304.654 447.979 1.00 102.68 ? 164 ASN A ND2 1 
ATOM 2603 N N   . PRO C 3 165 ? 364.555 305.799 444.087 1.00 100.58 ? 165 PRO A N   1 
ATOM 2604 C CA  . PRO C 3 165 ? 365.666 306.096 443.175 1.00 100.58 ? 165 PRO A CA  1 
ATOM 2605 C C   . PRO C 3 165 ? 366.671 307.036 443.825 1.00 100.58 ? 165 PRO A C   1 
ATOM 2606 O O   . PRO C 3 165 ? 366.323 308.135 444.260 1.00 100.58 ? 165 PRO A O   1 
ATOM 2607 C CB  . PRO C 3 165 ? 364.977 306.750 441.974 1.00 100.58 ? 165 PRO A CB  1 
ATOM 2608 C CG  . PRO C 3 165 ? 363.687 307.252 442.483 1.00 100.58 ? 165 PRO A CG  1 
ATOM 2609 C CD  . PRO C 3 165 ? 363.319 306.505 443.722 1.00 100.58 ? 165 PRO A CD  1 
ATOM 2610 N N   . SER C 3 166 ? 367.923 306.593 443.889 1.00 94.65  ? 166 SER A N   1 
ATOM 2611 C CA  . SER C 3 166 ? 368.997 307.324 444.538 1.00 94.65  ? 166 SER A CA  1 
ATOM 2612 C C   . SER C 3 166 ? 370.183 307.451 443.598 1.00 94.65  ? 166 SER A C   1 
ATOM 2613 O O   . SER C 3 166 ? 370.475 306.542 442.821 1.00 94.65  ? 166 SER A O   1 
ATOM 2614 C CB  . SER C 3 166 ? 369.449 306.616 445.807 1.00 94.65  ? 166 SER A CB  1 
ATOM 2615 O OG  . SER C 3 166 ? 370.123 305.423 445.477 1.00 94.65  ? 166 SER A OG  1 
ATOM 2616 N N   . VAL C 3 167 ? 370.887 308.574 443.692 1.00 91.81  ? 167 VAL A N   1 
ATOM 2617 C CA  . VAL C 3 167 ? 372.042 308.819 442.841 1.00 91.81  ? 167 VAL A CA  1 
ATOM 2618 C C   . VAL C 3 167 ? 373.310 308.590 443.647 1.00 91.81  ? 167 VAL A C   1 
ATOM 2619 O O   . VAL C 3 167 ? 373.327 308.723 444.874 1.00 91.81  ? 167 VAL A O   1 
ATOM 2620 C CB  . VAL C 3 167 ? 372.029 310.235 442.232 1.00 91.81  ? 167 VAL A CB  1 
ATOM 2621 C CG1 . VAL C 3 167 ? 370.780 310.427 441.421 1.00 91.81  ? 167 VAL A CG1 1 
ATOM 2622 C CG2 . VAL C 3 167 ? 372.113 311.285 443.298 1.00 91.81  ? 167 VAL A CG2 1 
ATOM 2623 N N   . PHE C 3 168 ? 374.371 308.212 442.950 1.00 92.65  ? 168 PHE A N   1 
ATOM 2624 C CA  . PHE C 3 168 ? 375.672 307.987 443.557 1.00 92.65  ? 168 PHE A CA  1 
ATOM 2625 C C   . PHE C 3 168 ? 376.676 308.881 442.856 1.00 92.65  ? 168 PHE A C   1 
ATOM 2626 O O   . PHE C 3 168 ? 376.670 308.983 441.628 1.00 92.65  ? 168 PHE A O   1 
ATOM 2627 C CB  . PHE C 3 168 ? 376.102 306.529 443.447 1.00 92.65  ? 168 PHE A CB  1 
ATOM 2628 C CG  . PHE C 3 168 ? 375.370 305.609 444.371 1.00 92.65  ? 168 PHE A CG  1 
ATOM 2629 C CD1 . PHE C 3 168 ? 374.118 305.126 444.041 1.00 92.65  ? 168 PHE A CD1 1 
ATOM 2630 C CD2 . PHE C 3 168 ? 375.939 305.214 445.563 1.00 92.65  ? 168 PHE A CD2 1 
ATOM 2631 C CE1 . PHE C 3 168 ? 373.448 304.276 444.888 1.00 92.65  ? 168 PHE A CE1 1 
ATOM 2632 C CE2 . PHE C 3 168 ? 375.271 304.364 446.413 1.00 92.65  ? 168 PHE A CE2 1 
ATOM 2633 C CZ  . PHE C 3 168 ? 374.025 303.895 446.074 1.00 92.65  ? 168 PHE A CZ  1 
ATOM 2634 N N   . TRP C 3 169 ? 377.542 309.520 443.631 1.00 99.63  ? 169 TRP A N   1 
ATOM 2635 C CA  . TRP C 3 169 ? 378.335 310.617 443.101 1.00 99.63  ? 169 TRP A CA  1 
ATOM 2636 C C   . TRP C 3 169 ? 379.664 310.678 443.828 1.00 99.63  ? 169 TRP A C   1 
ATOM 2637 O O   . TRP C 3 169 ? 379.688 310.738 445.057 1.00 99.63  ? 169 TRP A O   1 
ATOM 2638 C CB  . TRP C 3 169 ? 377.575 311.933 443.266 1.00 99.63  ? 169 TRP A CB  1 
ATOM 2639 C CG  . TRP C 3 169 ? 378.285 313.124 442.759 1.00 99.63  ? 169 TRP A CG  1 
ATOM 2640 C CD1 . TRP C 3 169 ? 378.425 313.498 441.463 1.00 99.63  ? 169 TRP A CD1 1 
ATOM 2641 C CD2 . TRP C 3 169 ? 378.942 314.123 443.540 1.00 99.63  ? 169 TRP A CD2 1 
ATOM 2642 N NE1 . TRP C 3 169 ? 379.138 314.665 441.382 1.00 99.63  ? 169 TRP A NE1 1 
ATOM 2643 C CE2 . TRP C 3 169 ? 379.466 315.070 442.647 1.00 99.63  ? 169 TRP A CE2 1 
ATOM 2644 C CE3 . TRP C 3 169 ? 379.142 314.306 444.908 1.00 99.63  ? 169 TRP A CE3 1 
ATOM 2645 C CZ2 . TRP C 3 169 ? 380.179 316.180 443.076 1.00 99.63  ? 169 TRP A CZ2 1 
ATOM 2646 C CZ3 . TRP C 3 169 ? 379.847 315.407 445.330 1.00 99.63  ? 169 TRP A CZ3 1 
ATOM 2647 C CH2 . TRP C 3 169 ? 380.357 316.331 444.419 1.00 99.63  ? 169 TRP A CH2 1 
ATOM 2648 N N   . THR C 3 170 ? 380.757 310.658 443.077 1.00 101.94 ? 170 THR A N   1 
ATOM 2649 C CA  . THR C 3 170 ? 382.085 310.840 443.640 1.00 101.94 ? 170 THR A CA  1 
ATOM 2650 C C   . THR C 3 170 ? 382.456 312.316 443.622 1.00 101.94 ? 170 THR A C   1 
ATOM 2651 O O   . THR C 3 170 ? 381.887 313.115 442.881 1.00 101.94 ? 170 THR A O   1 
ATOM 2652 C CB  . THR C 3 170 ? 383.121 310.030 442.866 1.00 101.94 ? 170 THR A CB  1 
ATOM 2653 O OG1 . THR C 3 170 ? 383.004 310.330 441.473 1.00 101.94 ? 170 THR A OG1 1 
ATOM 2654 C CG2 . THR C 3 170 ? 382.899 308.554 443.074 1.00 101.94 ? 170 THR A CG2 1 
ATOM 2655 N N   . GLU C 3 171 ? 383.428 312.676 444.452 1.00 106.85 ? 171 GLU A N   1 
ATOM 2656 C CA  . GLU C 3 171 ? 383.827 314.069 444.532 1.00 106.85 ? 171 GLU A CA  1 
ATOM 2657 C C   . GLU C 3 171 ? 384.815 314.407 443.421 1.00 106.85 ? 171 GLU A C   1 
ATOM 2658 O O   . GLU C 3 171 ? 385.610 313.577 442.980 1.00 106.85 ? 171 GLU A O   1 
ATOM 2659 C CB  . GLU C 3 171 ? 384.434 314.376 445.895 1.00 106.85 ? 171 GLU A CB  1 
ATOM 2660 C CG  . GLU C 3 171 ? 383.430 314.370 447.026 1.00 106.85 ? 171 GLU A CG  1 
ATOM 2661 C CD  . GLU C 3 171 ? 383.781 315.358 448.113 1.00 106.85 ? 171 GLU A CD  1 
ATOM 2662 O OE1 . GLU C 3 171 ? 383.813 314.961 449.295 1.00 106.85 ? 171 GLU A OE1 1 
ATOM 2663 O OE2 . GLU C 3 171 ? 384.032 316.534 447.783 1.00 106.85 ? 171 GLU A OE2 1 
ATOM 2664 N N   . GLY C 3 172 ? 384.761 315.657 442.973 1.00 109.98 ? 172 GLY A N   1 
ATOM 2665 C CA  . GLY C 3 172 ? 385.619 316.091 441.893 1.00 109.98 ? 172 GLY A CA  1 
ATOM 2666 C C   . GLY C 3 172 ? 385.024 315.951 440.513 1.00 109.98 ? 172 GLY A C   1 
ATOM 2667 O O   . GLY C 3 172 ? 385.768 315.847 439.538 1.00 109.98 ? 172 GLY A O   1 
ATOM 2668 N N   . ASN C 3 173 ? 383.699 315.945 440.400 1.00 107.74 ? 173 ASN A N   1 
ATOM 2669 C CA  . ASN C 3 173 ? 383.042 315.853 439.103 1.00 107.74 ? 173 ASN A CA  1 
ATOM 2670 C C   . ASN C 3 173 ? 381.965 316.918 438.983 1.00 107.74 ? 173 ASN A C   1 
ATOM 2671 O O   . ASN C 3 173 ? 381.894 317.828 439.814 1.00 107.74 ? 173 ASN A O   1 
ATOM 2672 C CB  . ASN C 3 173 ? 382.437 314.467 438.902 1.00 107.74 ? 173 ASN A CB  1 
ATOM 2673 C CG  . ASN C 3 173 ? 383.480 313.382 438.866 1.00 107.74 ? 173 ASN A CG  1 
ATOM 2674 O OD1 . ASN C 3 173 ? 383.992 313.037 437.806 1.00 107.74 ? 173 ASN A OD1 1 
ATOM 2675 N ND2 . ASN C 3 173 ? 383.808 312.839 440.027 1.00 107.74 ? 173 ASN A ND2 1 
ATOM 2676 N N   . ALA C 3 174 ? 381.135 316.823 437.949 1.00 105.53 ? 174 ALA A N   1 
ATOM 2677 C CA  . ALA C 3 174 ? 380.000 317.718 437.820 1.00 105.53 ? 174 ALA A CA  1 
ATOM 2678 C C   . ALA C 3 174 ? 378.967 317.408 438.903 1.00 105.53 ? 174 ALA A C   1 
ATOM 2679 O O   . ALA C 3 174 ? 378.846 316.260 439.337 1.00 105.53 ? 174 ALA A O   1 
ATOM 2680 C CB  . ALA C 3 174 ? 379.373 317.582 436.438 1.00 105.53 ? 174 ALA A CB  1 
ATOM 2681 N N   . PRO C 3 175 ? 378.239 318.421 439.382 1.00 98.51  ? 175 PRO A N   1 
ATOM 2682 C CA  . PRO C 3 175 ? 377.296 318.189 440.473 1.00 98.51  ? 175 PRO A CA  1 
ATOM 2683 C C   . PRO C 3 175 ? 376.109 317.360 440.021 1.00 98.51  ? 175 PRO A C   1 
ATOM 2684 O O   . PRO C 3 175 ? 375.661 317.464 438.867 1.00 98.51  ? 175 PRO A O   1 
ATOM 2685 C CB  . PRO C 3 175 ? 376.867 319.611 440.875 1.00 98.51  ? 175 PRO A CB  1 
ATOM 2686 C CG  . PRO C 3 175 ? 377.263 320.461 439.754 1.00 98.51  ? 175 PRO A CG  1 
ATOM 2687 C CD  . PRO C 3 175 ? 378.484 319.855 439.189 1.00 98.51  ? 175 PRO A CD  1 
ATOM 2688 N N   . PRO C 3 176 ? 375.560 316.517 440.903 1.00 98.00  ? 176 PRO A N   1 
ATOM 2689 C CA  . PRO C 3 176 ? 374.578 315.507 440.481 1.00 98.00  ? 176 PRO A CA  1 
ATOM 2690 C C   . PRO C 3 176 ? 373.148 316.001 440.317 1.00 98.00  ? 176 PRO A C   1 
ATOM 2691 O O   . PRO C 3 176 ? 372.363 315.961 441.264 1.00 98.00  ? 176 PRO A O   1 
ATOM 2692 C CB  . PRO C 3 176 ? 374.673 314.458 441.592 1.00 98.00  ? 176 PRO A CB  1 
ATOM 2693 C CG  . PRO C 3 176 ? 375.140 315.197 442.773 1.00 98.00  ? 176 PRO A CG  1 
ATOM 2694 C CD  . PRO C 3 176 ? 376.002 316.309 442.291 1.00 98.00  ? 176 PRO A CD  1 
ATOM 2695 N N   . ARG C 3 177 ? 372.802 316.486 439.133 1.00 99.25  ? 177 ARG A N   1 
ATOM 2696 C CA  . ARG C 3 177 ? 371.425 316.866 438.851 1.00 99.25  ? 177 ARG A CA  1 
ATOM 2697 C C   . ARG C 3 177 ? 370.520 315.641 438.775 1.00 99.25  ? 177 ARG A C   1 
ATOM 2698 O O   . ARG C 3 177 ? 370.969 314.537 438.464 1.00 99.25  ? 177 ARG A O   1 
ATOM 2699 C CB  . ARG C 3 177 ? 371.360 317.635 437.534 1.00 99.25  ? 177 ARG A CB  1 
ATOM 2700 C CG  . ARG C 3 177 ? 370.188 318.575 437.407 1.00 99.25  ? 177 ARG A CG  1 
ATOM 2701 C CD  . ARG C 3 177 ? 370.044 319.061 435.991 1.00 99.25  ? 177 ARG A CD  1 
ATOM 2702 N NE  . ARG C 3 177 ? 371.122 319.960 435.603 1.00 99.25  ? 177 ARG A NE  1 
ATOM 2703 C CZ  . ARG C 3 177 ? 371.042 321.283 435.663 1.00 99.25  ? 177 ARG A CZ  1 
ATOM 2704 N NH1 . ARG C 3 177 ? 369.935 321.857 436.098 1.00 99.25  ? 177 ARG A NH1 1 
ATOM 2705 N NH2 . ARG C 3 177 ? 372.065 322.033 435.288 1.00 99.25  ? 177 ARG A NH2 1 
ATOM 2706 N N   . MET C 3 178 ? 369.238 315.842 439.083 1.00 103.80 ? 178 MET A N   1 
ATOM 2707 C CA  . MET C 3 178 ? 368.182 314.871 438.828 1.00 103.80 ? 178 MET A CA  1 
ATOM 2708 C C   . MET C 3 178 ? 366.861 315.618 438.718 1.00 103.80 ? 178 MET A C   1 
ATOM 2709 O O   . MET C 3 178 ? 366.730 316.744 439.199 1.00 103.80 ? 178 MET A O   1 
ATOM 2710 C CB  . MET C 3 178 ? 368.101 313.796 439.917 1.00 103.80 ? 178 MET A CB  1 
ATOM 2711 C CG  . MET C 3 178 ? 367.487 314.260 441.212 1.00 103.80 ? 178 MET A CG  1 
ATOM 2712 S SD  . MET C 3 178 ? 367.980 313.247 442.613 1.00 103.80 ? 178 MET A SD  1 
ATOM 2713 C CE  . MET C 3 178 ? 367.251 311.684 442.161 1.00 103.80 ? 178 MET A CE  1 
ATOM 2714 N N   . SER C 3 179 ? 365.883 314.990 438.071 1.00 105.77 ? 179 SER A N   1 
ATOM 2715 C CA  . SER C 3 179 ? 364.629 315.649 437.730 1.00 105.77 ? 179 SER A CA  1 
ATOM 2716 C C   . SER C 3 179 ? 363.448 314.824 438.210 1.00 105.77 ? 179 SER A C   1 
ATOM 2717 O O   . SER C 3 179 ? 363.365 313.629 437.920 1.00 105.77 ? 179 SER A O   1 
ATOM 2718 C CB  . SER C 3 179 ? 364.519 315.865 436.225 1.00 105.77 ? 179 SER A CB  1 
ATOM 2719 O OG  . SER C 3 179 ? 363.164 315.985 435.843 1.00 105.77 ? 179 SER A OG  1 
ATOM 2720 N N   . ILE C 3 180 ? 362.526 315.470 438.906 1.00 101.69 ? 180 ILE A N   1 
ATOM 2721 C CA  . ILE C 3 180 ? 361.368 314.821 439.517 1.00 101.69 ? 180 ILE A CA  1 
ATOM 2722 C C   . ILE C 3 180 ? 360.128 315.253 438.747 1.00 101.69 ? 180 ILE A C   1 
ATOM 2723 O O   . ILE C 3 180 ? 359.928 316.455 438.548 1.00 101.69 ? 180 ILE A O   1 
ATOM 2724 C CB  . ILE C 3 180 ? 361.241 315.187 441.009 1.00 101.69 ? 180 ILE A CB  1 
ATOM 2725 C CG1 . ILE C 3 180 ? 362.311 314.462 441.814 1.00 101.69 ? 180 ILE A CG1 1 
ATOM 2726 C CG2 . ILE C 3 180 ? 359.874 314.855 441.557 1.00 101.69 ? 180 ILE A CG2 1 
ATOM 2727 C CD1 . ILE C 3 180 ? 362.602 315.102 443.130 1.00 101.69 ? 180 ILE A CD1 1 
ATOM 2728 N N   . PRO C 3 181 ? 359.285 314.331 438.299 1.00 103.72 ? 181 PRO A N   1 
ATOM 2729 C CA  . PRO C 3 181 ? 358.094 314.705 437.533 1.00 103.72 ? 181 PRO A CA  1 
ATOM 2730 C C   . PRO C 3 181 ? 356.992 315.229 438.448 1.00 103.72 ? 181 PRO A C   1 
ATOM 2731 O O   . PRO C 3 181 ? 357.162 315.372 439.654 1.00 103.72 ? 181 PRO A O   1 
ATOM 2732 C CB  . PRO C 3 181 ? 357.692 313.392 436.872 1.00 103.72 ? 181 PRO A CB  1 
ATOM 2733 C CG  . PRO C 3 181 ? 358.109 312.371 437.850 1.00 103.72 ? 181 PRO A CG  1 
ATOM 2734 C CD  . PRO C 3 181 ? 359.388 312.872 438.457 1.00 103.72 ? 181 PRO A CD  1 
ATOM 2735 N N   . PHE C 3 182 ? 355.844 315.513 437.846 1.00 104.91 ? 182 PHE A N   1 
ATOM 2736 C CA  . PHE C 3 182 ? 354.694 316.030 438.583 1.00 104.91 ? 182 PHE A CA  1 
ATOM 2737 C C   . PHE C 3 182 ? 353.941 314.863 439.206 1.00 104.91 ? 182 PHE A C   1 
ATOM 2738 O O   . PHE C 3 182 ? 353.212 314.144 438.523 1.00 104.91 ? 182 PHE A O   1 
ATOM 2739 C CB  . PHE C 3 182 ? 353.792 316.833 437.655 1.00 104.91 ? 182 PHE A CB  1 
ATOM 2740 C CG  . PHE C 3 182 ? 352.460 317.165 438.248 1.00 104.91 ? 182 PHE A CG  1 
ATOM 2741 C CD1 . PHE C 3 182 ? 352.371 317.962 439.366 1.00 104.91 ? 182 PHE A CD1 1 
ATOM 2742 C CD2 . PHE C 3 182 ? 351.298 316.682 437.686 1.00 104.91 ? 182 PHE A CD2 1 
ATOM 2743 C CE1 . PHE C 3 182 ? 351.151 318.273 439.916 1.00 104.91 ? 182 PHE A CE1 1 
ATOM 2744 C CE2 . PHE C 3 182 ? 350.074 316.989 438.233 1.00 104.91 ? 182 PHE A CE2 1 
ATOM 2745 C CZ  . PHE C 3 182 ? 350.003 317.784 439.350 1.00 104.91 ? 182 PHE A CZ  1 
ATOM 2746 N N   . ILE C 3 183 ? 354.112 314.665 440.509 1.00 105.26 ? 183 ILE A N   1 
ATOM 2747 C CA  . ILE C 3 183 ? 353.474 313.569 441.227 1.00 105.26 ? 183 ILE A CA  1 
ATOM 2748 C C   . ILE C 3 183 ? 352.355 314.125 442.095 1.00 105.26 ? 183 ILE A C   1 
ATOM 2749 O O   . ILE C 3 183 ? 352.604 314.876 443.045 1.00 105.26 ? 183 ILE A O   1 
ATOM 2750 C CB  . ILE C 3 183 ? 354.485 312.772 442.067 1.00 105.26 ? 183 ILE A CB  1 
ATOM 2751 C CG1 . ILE C 3 183 ? 355.525 313.688 442.699 1.00 105.26 ? 183 ILE A CG1 1 
ATOM 2752 C CG2 . ILE C 3 183 ? 355.183 311.744 441.218 1.00 105.26 ? 183 ILE A CG2 1 
ATOM 2753 C CD1 . ILE C 3 183 ? 356.285 313.024 443.776 1.00 105.26 ? 183 ILE A CD1 1 
ATOM 2754 N N   . SER C 3 184 ? 351.122 313.747 441.765 1.00 105.75 ? 184 SER A N   1 
ATOM 2755 C CA  . SER C 3 184 ? 349.944 314.085 442.552 1.00 105.75 ? 184 SER A CA  1 
ATOM 2756 C C   . SER C 3 184 ? 348.782 313.215 442.106 1.00 105.75 ? 184 SER A C   1 
ATOM 2757 O O   . SER C 3 184 ? 348.829 312.610 441.032 1.00 105.75 ? 184 SER A O   1 
ATOM 2758 C CB  . SER C 3 184 ? 349.568 315.561 442.399 1.00 105.75 ? 184 SER A CB  1 
ATOM 2759 O OG  . SER C 3 184 ? 348.739 315.986 443.463 1.00 105.75 ? 184 SER A OG  1 
ATOM 2760 N N   . ILE C 3 185 ? 347.738 313.140 442.922 1.00 104.30 ? 185 ILE A N   1 
ATOM 2761 C CA  . ILE C 3 185 ? 346.463 312.599 442.490 1.00 104.30 ? 185 ILE A CA  1 
ATOM 2762 C C   . ILE C 3 185 ? 345.606 313.674 441.840 1.00 104.30 ? 185 ILE A C   1 
ATOM 2763 O O   . ILE C 3 185 ? 344.926 313.418 440.847 1.00 104.30 ? 185 ILE A O   1 
ATOM 2764 C CB  . ILE C 3 185 ? 345.729 311.944 443.678 1.00 104.30 ? 185 ILE A CB  1 
ATOM 2765 C CG1 . ILE C 3 185 ? 346.684 311.047 444.462 1.00 104.30 ? 185 ILE A CG1 1 
ATOM 2766 C CG2 . ILE C 3 185 ? 344.534 311.144 443.197 1.00 104.30 ? 185 ILE A CG2 1 
ATOM 2767 C CD1 . ILE C 3 185 ? 347.155 309.834 443.696 1.00 104.30 ? 185 ILE A CD1 1 
ATOM 2768 N N   . GLY C 3 186 ? 345.659 314.890 442.372 1.00 105.98 ? 186 GLY A N   1 
ATOM 2769 C CA  . GLY C 3 186 ? 344.919 316.004 441.824 1.00 105.98 ? 186 GLY A CA  1 
ATOM 2770 C C   . GLY C 3 186 ? 345.539 316.511 440.541 1.00 105.98 ? 186 GLY A C   1 
ATOM 2771 O O   . GLY C 3 186 ? 346.639 316.120 440.147 1.00 105.98 ? 186 GLY A O   1 
ATOM 2772 N N   . ASN C 3 187 ? 344.814 317.410 439.884 1.00 107.75 ? 187 ASN A N   1 
ATOM 2773 C CA  . ASN C 3 187 ? 345.227 317.933 438.594 1.00 107.75 ? 187 ASN A CA  1 
ATOM 2774 C C   . ASN C 3 187 ? 346.127 319.152 438.697 1.00 107.75 ? 187 ASN A C   1 
ATOM 2775 O O   . ASN C 3 187 ? 346.570 319.657 437.662 1.00 107.75 ? 187 ASN A O   1 
ATOM 2776 C CB  . ASN C 3 187 ? 343.992 318.276 437.756 1.00 107.75 ? 187 ASN A CB  1 
ATOM 2777 C CG  . ASN C 3 187 ? 343.014 317.128 437.674 1.00 107.75 ? 187 ASN A CG  1 
ATOM 2778 O OD1 . ASN C 3 187 ? 341.986 317.128 438.342 1.00 107.75 ? 187 ASN A OD1 1 
ATOM 2779 N ND2 . ASN C 3 187 ? 343.324 316.144 436.845 1.00 107.75 ? 187 ASN A ND2 1 
ATOM 2780 N N   . ALA C 3 188 ? 346.411 319.626 439.907 1.00 106.40 ? 188 ALA A N   1 
ATOM 2781 C CA  . ALA C 3 188 ? 347.314 320.744 440.131 1.00 106.40 ? 188 ALA A CA  1 
ATOM 2782 C C   . ALA C 3 188 ? 347.766 320.716 441.581 1.00 106.40 ? 188 ALA A C   1 
ATOM 2783 O O   . ALA C 3 188 ? 347.104 320.133 442.441 1.00 106.40 ? 188 ALA A O   1 
ATOM 2784 C CB  . ALA C 3 188 ? 346.648 322.085 439.815 1.00 106.40 ? 188 ALA A CB  1 
ATOM 2785 N N   . TYR C 3 189 ? 348.901 321.353 441.845 1.00 102.88 ? 189 TYR A N   1 
ATOM 2786 C CA  . TYR C 3 189 ? 349.254 321.634 443.223 1.00 102.88 ? 189 TYR A CA  1 
ATOM 2787 C C   . TYR C 3 189 ? 348.332 322.720 443.761 1.00 102.88 ? 189 TYR A C   1 
ATOM 2788 O O   . TYR C 3 189 ? 347.716 323.472 443.009 1.00 102.88 ? 189 TYR A O   1 
ATOM 2789 C CB  . TYR C 3 189 ? 350.707 322.086 443.342 1.00 102.88 ? 189 TYR A CB  1 
ATOM 2790 C CG  . TYR C 3 189 ? 351.754 321.028 443.074 1.00 102.88 ? 189 TYR A CG  1 
ATOM 2791 C CD1 . TYR C 3 189 ? 351.933 319.965 443.941 1.00 102.88 ? 189 TYR A CD1 1 
ATOM 2792 C CD2 . TYR C 3 189 ? 352.593 321.120 441.978 1.00 102.88 ? 189 TYR A CD2 1 
ATOM 2793 C CE1 . TYR C 3 189 ? 352.895 319.008 443.709 1.00 102.88 ? 189 TYR A CE1 1 
ATOM 2794 C CE2 . TYR C 3 189 ? 353.562 320.170 441.743 1.00 102.88 ? 189 TYR A CE2 1 
ATOM 2795 C CZ  . TYR C 3 189 ? 353.703 319.117 442.610 1.00 102.88 ? 189 TYR A CZ  1 
ATOM 2796 O OH  . TYR C 3 189 ? 354.665 318.169 442.375 1.00 102.88 ? 189 TYR A OH  1 
ATOM 2797 N N   . SER C 3 190 ? 348.243 322.812 445.081 1.00 104.63 ? 190 SER A N   1 
ATOM 2798 C CA  . SER C 3 190 ? 347.382 323.817 445.696 1.00 104.63 ? 190 SER A CA  1 
ATOM 2799 C C   . SER C 3 190 ? 348.215 324.618 446.681 1.00 104.63 ? 190 SER A C   1 
ATOM 2800 O O   . SER C 3 190 ? 348.649 324.082 447.703 1.00 104.63 ? 190 SER A O   1 
ATOM 2801 C CB  . SER C 3 190 ? 346.191 323.175 446.391 1.00 104.63 ? 190 SER A CB  1 
ATOM 2802 O OG  . SER C 3 190 ? 345.660 324.045 447.370 1.00 104.63 ? 190 SER A OG  1 
ATOM 2803 N N   . CYS C 3 191 ? 348.435 325.896 446.379 1.00 104.92 ? 191 CYS A N   1 
ATOM 2804 C CA  . CYS C 3 191 ? 349.222 326.727 447.277 1.00 104.92 ? 191 CYS A CA  1 
ATOM 2805 C C   . CYS C 3 191 ? 348.417 327.208 448.473 1.00 104.92 ? 191 CYS A C   1 
ATOM 2806 O O   . CYS C 3 191 ? 349.008 327.608 449.480 1.00 104.92 ? 191 CYS A O   1 
ATOM 2807 C CB  . CYS C 3 191 ? 349.793 327.917 446.517 1.00 104.92 ? 191 CYS A CB  1 
ATOM 2808 S SG  . CYS C 3 191 ? 350.973 327.447 445.247 1.00 104.92 ? 191 CYS A SG  1 
ATOM 2809 N N   . PHE C 3 192 ? 347.092 327.181 448.388 1.00 108.39 ? 192 PHE A N   1 
ATOM 2810 C CA  . PHE C 3 192 ? 346.222 327.592 449.477 1.00 108.39 ? 192 PHE A CA  1 
ATOM 2811 C C   . PHE C 3 192 ? 345.089 326.590 449.619 1.00 108.39 ? 192 PHE A C   1 
ATOM 2812 O O   . PHE C 3 192 ? 344.628 326.011 448.634 1.00 108.39 ? 192 PHE A O   1 
ATOM 2813 C CB  . PHE C 3 192 ? 345.652 328.984 449.241 1.00 108.39 ? 192 PHE A CB  1 
ATOM 2814 C CG  . PHE C 3 192 ? 346.622 330.082 449.514 1.00 108.39 ? 192 PHE A CG  1 
ATOM 2815 C CD1 . PHE C 3 192 ? 347.523 330.482 448.550 1.00 108.39 ? 192 PHE A CD1 1 
ATOM 2816 C CD2 . PHE C 3 192 ? 346.630 330.720 450.738 1.00 108.39 ? 192 PHE A CD2 1 
ATOM 2817 C CE1 . PHE C 3 192 ? 348.420 331.487 448.804 1.00 108.39 ? 192 PHE A CE1 1 
ATOM 2818 C CE2 . PHE C 3 192 ? 347.523 331.733 450.998 1.00 108.39 ? 192 PHE A CE2 1 
ATOM 2819 C CZ  . PHE C 3 192 ? 348.418 332.117 450.029 1.00 108.39 ? 192 PHE A CZ  1 
ATOM 2820 N N   . TYR C 3 193 ? 344.641 326.393 450.854 1.00 112.55 ? 193 TYR A N   1 
ATOM 2821 C CA  . TYR C 3 193 ? 343.626 325.387 451.138 1.00 112.55 ? 193 TYR A CA  1 
ATOM 2822 C C   . TYR C 3 193 ? 342.794 325.850 452.318 1.00 112.55 ? 193 TYR A C   1 
ATOM 2823 O O   . TYR C 3 193 ? 343.294 325.899 453.444 1.00 112.55 ? 193 TYR A O   1 
ATOM 2824 C CB  . TYR C 3 193 ? 344.273 324.041 451.436 1.00 112.55 ? 193 TYR A CB  1 
ATOM 2825 C CG  . TYR C 3 193 ? 343.310 322.887 451.520 1.00 112.55 ? 193 TYR A CG  1 
ATOM 2826 C CD1 . TYR C 3 193 ? 342.744 322.350 450.377 1.00 112.55 ? 193 TYR A CD1 1 
ATOM 2827 C CD2 . TYR C 3 193 ? 343.000 322.309 452.739 1.00 112.55 ? 193 TYR A CD2 1 
ATOM 2828 C CE1 . TYR C 3 193 ? 341.877 321.285 450.448 1.00 112.55 ? 193 TYR A CE1 1 
ATOM 2829 C CE2 . TYR C 3 193 ? 342.135 321.242 452.820 1.00 112.55 ? 193 TYR A CE2 1 
ATOM 2830 C CZ  . TYR C 3 193 ? 341.576 320.737 451.673 1.00 112.55 ? 193 TYR A CZ  1 
ATOM 2831 O OH  . TYR C 3 193 ? 340.711 319.673 451.752 1.00 112.55 ? 193 TYR A OH  1 
ATOM 2832 N N   . ASP C 3 194 ? 341.536 326.188 452.065 1.00 109.64 ? 194 ASP A N   1 
ATOM 2833 C CA  . ASP C 3 194 ? 340.606 326.580 453.119 1.00 109.64 ? 194 ASP A CA  1 
ATOM 2834 C C   . ASP C 3 194 ? 339.770 325.357 453.457 1.00 109.64 ? 194 ASP A C   1 
ATOM 2835 O O   . ASP C 3 194 ? 338.675 325.165 452.931 1.00 109.64 ? 194 ASP A O   1 
ATOM 2836 C CB  . ASP C 3 194 ? 339.733 327.746 452.686 1.00 109.64 ? 194 ASP A CB  1 
ATOM 2837 C CG  . ASP C 3 194 ? 338.831 328.229 453.794 1.00 109.64 ? 194 ASP A CG  1 
ATOM 2838 O OD1 . ASP C 3 194 ? 339.180 328.032 454.975 1.00 109.64 ? 194 ASP A OD1 1 
ATOM 2839 O OD2 . ASP C 3 194 ? 337.770 328.806 453.489 1.00 109.64 ? 194 ASP A OD2 1 
ATOM 2840 N N   . GLY C 3 195 ? 340.294 324.524 454.344 1.00 109.83 ? 195 GLY A N   1 
ATOM 2841 C CA  . GLY C 3 195 ? 339.596 323.316 454.714 1.00 109.83 ? 195 GLY A CA  1 
ATOM 2842 C C   . GLY C 3 195 ? 340.478 322.440 455.575 1.00 109.83 ? 195 GLY A C   1 
ATOM 2843 O O   . GLY C 3 195 ? 341.680 322.667 455.700 1.00 109.83 ? 195 GLY A O   1 
ATOM 2844 N N   . TRP C 3 196 ? 339.853 321.431 456.158 1.00 113.17 ? 196 TRP A N   1 
ATOM 2845 C CA  . TRP C 3 196 ? 340.511 320.540 457.092 1.00 113.17 ? 196 TRP A CA  1 
ATOM 2846 C C   . TRP C 3 196 ? 341.072 319.343 456.343 1.00 113.17 ? 196 TRP A C   1 
ATOM 2847 O O   . TRP C 3 196 ? 340.823 319.153 455.152 1.00 113.17 ? 196 TRP A O   1 
ATOM 2848 C CB  . TRP C 3 196 ? 339.539 320.115 458.193 1.00 113.17 ? 196 TRP A CB  1 
ATOM 2849 C CG  . TRP C 3 196 ? 339.175 321.262 459.074 1.00 113.17 ? 196 TRP A CG  1 
ATOM 2850 C CD1 . TRP C 3 196 ? 339.750 321.593 460.260 1.00 113.17 ? 196 TRP A CD1 1 
ATOM 2851 C CD2 . TRP C 3 196 ? 338.174 322.254 458.825 1.00 113.17 ? 196 TRP A CD2 1 
ATOM 2852 N NE1 . TRP C 3 196 ? 339.164 322.720 460.774 1.00 113.17 ? 196 TRP A NE1 1 
ATOM 2853 C CE2 . TRP C 3 196 ? 338.192 323.145 459.909 1.00 113.17 ? 196 TRP A CE2 1 
ATOM 2854 C CE3 . TRP C 3 196 ? 337.258 322.470 457.793 1.00 113.17 ? 196 TRP A CE3 1 
ATOM 2855 C CZ2 . TRP C 3 196 ? 337.335 324.232 459.990 1.00 113.17 ? 196 TRP A CZ2 1 
ATOM 2856 C CZ3 . TRP C 3 196 ? 336.410 323.550 457.876 1.00 113.17 ? 196 TRP A CZ3 1 
ATOM 2857 C CH2 . TRP C 3 196 ? 336.452 324.417 458.965 1.00 113.17 ? 196 TRP A CH2 1 
ATOM 2858 N N   . THR C 3 197 ? 341.857 318.543 457.052 1.00 113.76 ? 197 THR A N   1 
ATOM 2859 C CA  . THR C 3 197 ? 342.598 317.461 456.423 1.00 113.76 ? 197 THR A CA  1 
ATOM 2860 C C   . THR C 3 197 ? 341.700 316.283 456.069 1.00 113.76 ? 197 THR A C   1 
ATOM 2861 O O   . THR C 3 197 ? 341.522 315.956 454.897 1.00 113.76 ? 197 THR A O   1 
ATOM 2862 C CB  . THR C 3 197 ? 343.727 316.971 457.325 1.00 113.76 ? 197 THR A CB  1 
ATOM 2863 O OG1 . THR C 3 197 ? 344.614 316.142 456.568 1.00 113.76 ? 197 THR A OG1 1 
ATOM 2864 C CG2 . THR C 3 197 ? 343.164 316.176 458.484 1.00 113.76 ? 197 THR A CG2 1 
ATOM 2865 N N   . VAL C 3 204 ? 342.872 318.918 461.435 1.00 109.71 ? 204 VAL A N   1 
ATOM 2866 C CA  . VAL C 3 204 ? 343.814 320.027 461.423 1.00 109.71 ? 204 VAL A CA  1 
ATOM 2867 C C   . VAL C 3 204 ? 343.507 320.933 460.227 1.00 109.71 ? 204 VAL A C   1 
ATOM 2868 O O   . VAL C 3 204 ? 343.225 320.459 459.131 1.00 109.71 ? 204 VAL A O   1 
ATOM 2869 C CB  . VAL C 3 204 ? 345.273 319.502 461.433 1.00 109.71 ? 204 VAL A CB  1 
ATOM 2870 C CG1 . VAL C 3 204 ? 345.511 318.502 460.318 1.00 109.71 ? 204 VAL A CG1 1 
ATOM 2871 C CG2 . VAL C 3 204 ? 346.278 320.640 461.380 1.00 109.71 ? 204 VAL A CG2 1 
ATOM 2872 N N   . TYR C 3 205 ? 343.521 322.244 460.458 1.00 110.14 ? 205 TYR A N   1 
ATOM 2873 C CA  . TYR C 3 205 ? 343.037 323.210 459.484 1.00 110.14 ? 205 TYR A CA  1 
ATOM 2874 C C   . TYR C 3 205 ? 344.140 323.615 458.520 1.00 110.14 ? 205 TYR A C   1 
ATOM 2875 O O   . TYR C 3 205 ? 345.234 323.994 458.943 1.00 110.14 ? 205 TYR A O   1 
ATOM 2876 C CB  . TYR C 3 205 ? 342.491 324.449 460.188 1.00 110.14 ? 205 TYR A CB  1 
ATOM 2877 C CG  . TYR C 3 205 ? 342.118 325.567 459.248 1.00 110.14 ? 205 TYR A CG  1 
ATOM 2878 C CD1 . TYR C 3 205 ? 341.013 325.459 458.423 1.00 110.14 ? 205 TYR A CD1 1 
ATOM 2879 C CD2 . TYR C 3 205 ? 342.865 326.732 459.190 1.00 110.14 ? 205 TYR A CD2 1 
ATOM 2880 C CE1 . TYR C 3 205 ? 340.666 326.473 457.563 1.00 110.14 ? 205 TYR A CE1 1 
ATOM 2881 C CE2 . TYR C 3 205 ? 342.526 327.750 458.334 1.00 110.14 ? 205 TYR A CE2 1 
ATOM 2882 C CZ  . TYR C 3 205 ? 341.425 327.614 457.525 1.00 110.14 ? 205 TYR A CZ  1 
ATOM 2883 O OH  . TYR C 3 205 ? 341.079 328.627 456.667 1.00 110.14 ? 205 TYR A OH  1 
ATOM 2884 N N   . GLY C 3 206 ? 343.840 323.547 457.228 1.00 109.34 ? 206 GLY A N   1 
ATOM 2885 C CA  . GLY C 3 206 ? 344.720 324.063 456.202 1.00 109.34 ? 206 GLY A CA  1 
ATOM 2886 C C   . GLY C 3 206 ? 346.006 323.291 456.023 1.00 109.34 ? 206 GLY A C   1 
ATOM 2887 O O   . GLY C 3 206 ? 347.091 323.857 456.165 1.00 109.34 ? 206 GLY A O   1 
ATOM 2888 N N   . ILE C 3 207 ? 345.907 322.005 455.711 1.00 110.95 ? 207 ILE A N   1 
ATOM 2889 C CA  . ILE C 3 207 ? 347.068 321.155 455.490 1.00 110.95 ? 207 ILE A CA  1 
ATOM 2890 C C   . ILE C 3 207 ? 347.129 320.656 454.054 1.00 110.95 ? 207 ILE A C   1 
ATOM 2891 O O   . ILE C 3 207 ? 348.156 320.807 453.388 1.00 110.95 ? 207 ILE A O   1 
ATOM 2892 C CB  . ILE C 3 207 ? 347.098 319.982 456.493 1.00 110.95 ? 207 ILE A CB  1 
ATOM 2893 C CG1 . ILE C 3 207 ? 347.511 320.498 457.865 1.00 110.95 ? 207 ILE A CG1 1 
ATOM 2894 C CG2 . ILE C 3 207 ? 348.064 318.906 456.051 1.00 110.95 ? 207 ILE A CG2 1 
ATOM 2895 C CD1 . ILE C 3 207 ? 348.894 321.103 457.888 1.00 110.95 ? 207 ILE A CD1 1 
ATOM 2896 N N   . ASN C 3 208 ? 346.025 320.081 453.556 1.00 112.64 ? 208 ASN A N   1 
ATOM 2897 C CA  . ASN C 3 208 ? 345.894 319.564 452.189 1.00 112.64 ? 208 ASN A CA  1 
ATOM 2898 C C   . ASN C 3 208 ? 346.943 318.488 451.904 1.00 112.64 ? 208 ASN A C   1 
ATOM 2899 O O   . ASN C 3 208 ? 347.971 318.734 451.291 1.00 112.64 ? 208 ASN A O   1 
ATOM 2900 C CB  . ASN C 3 208 ? 345.956 320.665 451.124 1.00 112.64 ? 208 ASN A CB  1 
ATOM 2901 C CG  . ASN C 3 208 ? 345.656 320.142 449.736 1.00 112.64 ? 208 ASN A CG  1 
ATOM 2902 O OD1 . ASN C 3 208 ? 344.872 319.212 449.570 1.00 112.64 ? 208 ASN A OD1 1 
ATOM 2903 N ND2 . ASN C 3 208 ? 346.292 320.727 448.733 1.00 112.64 ? 208 ASN A ND2 1 
ATOM 2904 N N   . THR C 3 209 ? 346.691 317.297 452.438 1.00 113.46 ? 209 THR A N   1 
ATOM 2905 C CA  . THR C 3 209 ? 347.588 316.155 452.261 1.00 113.46 ? 209 THR A CA  1 
ATOM 2906 C C   . THR C 3 209 ? 347.755 315.684 450.811 1.00 113.46 ? 209 THR A C   1 
ATOM 2907 O O   . THR C 3 209 ? 348.486 314.716 450.593 1.00 113.46 ? 209 THR A O   1 
ATOM 2908 C CB  . THR C 3 209 ? 347.090 314.983 453.095 1.00 113.46 ? 209 THR A CB  1 
ATOM 2909 O OG1 . THR C 3 209 ? 347.894 313.832 452.817 1.00 113.46 ? 209 THR A OG1 1 
ATOM 2910 C CG2 . THR C 3 209 ? 345.650 314.677 452.746 1.00 113.46 ? 209 THR A CG2 1 
ATOM 2911 N N   . LEU C 3 210 ? 347.117 316.315 449.824 1.00 111.16 ? 210 LEU A N   1 
ATOM 2912 C CA  . LEU C 3 210 ? 347.165 315.814 448.460 1.00 111.16 ? 210 LEU A CA  1 
ATOM 2913 C C   . LEU C 3 210 ? 348.432 316.237 447.725 1.00 111.16 ? 210 LEU A C   1 
ATOM 2914 O O   . LEU C 3 210 ? 348.915 315.491 446.869 1.00 111.16 ? 210 LEU A O   1 
ATOM 2915 C CB  . LEU C 3 210 ? 345.928 316.282 447.705 1.00 111.16 ? 210 LEU A CB  1 
ATOM 2916 C CG  . LEU C 3 210 ? 345.515 315.444 446.507 1.00 111.16 ? 210 LEU A CG  1 
ATOM 2917 C CD1 . LEU C 3 210 ? 345.356 314.003 446.924 1.00 111.16 ? 210 LEU A CD1 1 
ATOM 2918 C CD2 . LEU C 3 210 ? 344.217 315.979 445.965 1.00 111.16 ? 210 LEU A CD2 1 
ATOM 2919 N N   . ASN C 3 211 ? 348.985 317.415 448.017 1.00 112.78 ? 211 ASN A N   1 
ATOM 2920 C CA  . ASN C 3 211 ? 350.234 317.842 447.391 1.00 112.78 ? 211 ASN A CA  1 
ATOM 2921 C C   . ASN C 3 211 ? 351.386 317.567 448.352 1.00 112.78 ? 211 ASN A C   1 
ATOM 2922 O O   . ASN C 3 211 ? 351.736 318.409 449.184 1.00 112.78 ? 211 ASN A O   1 
ATOM 2923 C CB  . ASN C 3 211 ? 350.197 319.306 446.952 1.00 112.78 ? 211 ASN A CB  1 
ATOM 2924 C CG  . ASN C 3 211 ? 349.580 320.220 447.969 1.00 112.78 ? 211 ASN A CG  1 
ATOM 2925 O OD1 . ASN C 3 211 ? 349.184 319.791 449.033 1.00 112.78 ? 211 ASN A OD1 1 
ATOM 2926 N ND2 . ASN C 3 211 ? 349.509 321.503 447.646 1.00 112.78 ? 211 ASN A ND2 1 
ATOM 2927 N N   . ASN C 3 212 ? 351.981 316.386 448.216 1.00 117.22 ? 212 ASN A N   1 
ATOM 2928 C CA  . ASN C 3 212 ? 353.065 315.938 449.082 1.00 117.22 ? 212 ASN A CA  1 
ATOM 2929 C C   . ASN C 3 212 ? 354.105 315.296 448.179 1.00 117.22 ? 212 ASN A C   1 
ATOM 2930 O O   . ASN C 3 212 ? 353.858 314.225 447.620 1.00 117.22 ? 212 ASN A O   1 
ATOM 2931 C CB  . ASN C 3 212 ? 352.548 314.957 450.130 1.00 117.22 ? 212 ASN A CB  1 
ATOM 2932 C CG  . ASN C 3 212 ? 353.652 314.349 450.956 1.00 117.22 ? 212 ASN A CG  1 
ATOM 2933 O OD1 . ASN C 3 212 ? 354.158 313.277 450.638 1.00 117.22 ? 212 ASN A OD1 1 
ATOM 2934 N ND2 . ASN C 3 212 ? 354.031 315.029 452.029 1.00 117.22 ? 212 ASN A ND2 1 
ATOM 2935 N N   . MET C 3 213 ? 355.256 315.945 448.028 1.00 111.50 ? 213 MET A N   1 
ATOM 2936 C CA  . MET C 3 213 ? 356.193 315.598 446.971 1.00 111.50 ? 213 MET A CA  1 
ATOM 2937 C C   . MET C 3 213 ? 357.274 314.614 447.395 1.00 111.50 ? 213 MET A C   1 
ATOM 2938 O O   . MET C 3 213 ? 357.926 314.032 446.524 1.00 111.50 ? 213 MET A O   1 
ATOM 2939 C CB  . MET C 3 213 ? 356.853 316.864 446.426 1.00 111.50 ? 213 MET A CB  1 
ATOM 2940 C CG  . MET C 3 213 ? 355.911 318.041 446.330 1.00 111.50 ? 213 MET A CG  1 
ATOM 2941 S SD  . MET C 3 213 ? 356.738 319.546 445.798 1.00 111.50 ? 213 MET A SD  1 
ATOM 2942 C CE  . MET C 3 213 ? 355.573 320.781 446.355 1.00 111.50 ? 213 MET A CE  1 
ATOM 2943 N N   . GLY C 3 214 ? 357.497 314.419 448.687 1.00 108.74 ? 214 GLY A N   1 
ATOM 2944 C CA  . GLY C 3 214 ? 358.479 313.441 449.106 1.00 108.74 ? 214 GLY A CA  1 
ATOM 2945 C C   . GLY C 3 214 ? 359.574 313.996 449.988 1.00 108.74 ? 214 GLY A C   1 
ATOM 2946 O O   . GLY C 3 214 ? 359.472 315.123 450.474 1.00 108.74 ? 214 GLY A O   1 
ATOM 2947 N N   . THR C 3 215 ? 360.630 313.217 450.205 1.00 103.43 ? 215 THR A N   1 
ATOM 2948 C CA  . THR C 3 215 ? 361.682 313.588 451.137 1.00 103.43 ? 215 THR A CA  1 
ATOM 2949 C C   . THR C 3 215 ? 363.019 313.167 450.543 1.00 103.43 ? 215 THR A C   1 
ATOM 2950 O O   . THR C 3 215 ? 363.104 312.154 449.847 1.00 103.43 ? 215 THR A O   1 
ATOM 2951 C CB  . THR C 3 215 ? 361.453 312.919 452.502 1.00 103.43 ? 215 THR A CB  1 
ATOM 2952 O OG1 . THR C 3 215 ? 360.085 313.081 452.885 1.00 103.43 ? 215 THR A OG1 1 
ATOM 2953 C CG2 . THR C 3 215 ? 362.283 313.578 453.575 1.00 103.43 ? 215 THR A CG2 1 
ATOM 2954 N N   . LEU C 3 216 ? 364.064 313.950 450.813 1.00 103.02 ? 216 LEU A N   1 
ATOM 2955 C CA  . LEU C 3 216 ? 365.406 313.672 450.323 1.00 103.02 ? 216 LEU A CA  1 
ATOM 2956 C C   . LEU C 3 216 ? 366.340 313.348 451.481 1.00 103.02 ? 216 LEU A C   1 
ATOM 2957 O O   . LEU C 3 216 ? 366.275 313.970 452.542 1.00 103.02 ? 216 LEU A O   1 
ATOM 2958 C CB  . LEU C 3 216 ? 365.965 314.856 449.547 1.00 103.02 ? 216 LEU A CB  1 
ATOM 2959 C CG  . LEU C 3 216 ? 365.407 315.077 448.148 1.00 103.02 ? 216 LEU A CG  1 
ATOM 2960 C CD1 . LEU C 3 216 ? 365.864 316.408 447.635 1.00 103.02 ? 216 LEU A CD1 1 
ATOM 2961 C CD2 . LEU C 3 216 ? 365.866 313.983 447.224 1.00 103.02 ? 216 LEU A CD2 1 
ATOM 2962 N N   . TYR C 3 217 ? 367.229 312.381 451.260 1.00 103.35 ? 217 TYR A N   1 
ATOM 2963 C CA  . TYR C 3 217 ? 368.156 311.921 452.283 1.00 103.35 ? 217 TYR A CA  1 
ATOM 2964 C C   . TYR C 3 217 ? 369.554 311.794 451.707 1.00 103.35 ? 217 TYR A C   1 
ATOM 2965 O O   . TYR C 3 217 ? 369.729 311.254 450.616 1.00 103.35 ? 217 TYR A O   1 
ATOM 2966 C CB  . TYR C 3 217 ? 367.727 310.576 452.850 1.00 103.35 ? 217 TYR A CB  1 
ATOM 2967 C CG  . TYR C 3 217 ? 366.413 310.637 453.552 1.00 103.35 ? 217 TYR A CG  1 
ATOM 2968 C CD1 . TYR C 3 217 ? 366.333 311.086 454.855 1.00 103.35 ? 217 TYR A CD1 1 
ATOM 2969 C CD2 . TYR C 3 217 ? 365.251 310.271 452.910 1.00 103.35 ? 217 TYR A CD2 1 
ATOM 2970 C CE1 . TYR C 3 217 ? 365.141 311.155 455.499 1.00 103.35 ? 217 TYR A CE1 1 
ATOM 2971 C CE2 . TYR C 3 217 ? 364.047 310.338 453.550 1.00 103.35 ? 217 TYR A CE2 1 
ATOM 2972 C CZ  . TYR C 3 217 ? 364.002 310.782 454.847 1.00 103.35 ? 217 TYR A CZ  1 
ATOM 2973 O OH  . TYR C 3 217 ? 362.802 310.864 455.497 1.00 103.35 ? 217 TYR A OH  1 
ATOM 2974 N N   . MET C 3 218 ? 370.547 312.271 452.453 1.00 106.70 ? 218 MET A N   1 
ATOM 2975 C CA  . MET C 3 218 ? 371.934 312.268 452.014 1.00 106.70 ? 218 MET A CA  1 
ATOM 2976 C C   . MET C 3 218 ? 372.798 311.588 453.063 1.00 106.70 ? 218 MET A C   1 
ATOM 2977 O O   . MET C 3 218 ? 372.561 311.758 454.259 1.00 106.70 ? 218 MET A O   1 
ATOM 2978 C CB  . MET C 3 218 ? 372.444 313.694 451.784 1.00 106.70 ? 218 MET A CB  1 
ATOM 2979 C CG  . MET C 3 218 ? 372.003 314.325 450.481 1.00 106.70 ? 218 MET A CG  1 
ATOM 2980 S SD  . MET C 3 218 ? 370.328 314.982 450.524 1.00 106.70 ? 218 MET A SD  1 
ATOM 2981 C CE  . MET C 3 218 ? 370.611 316.605 451.202 1.00 106.70 ? 218 MET A CE  1 
ATOM 2982 N N   . ARG C 3 219 ? 373.806 310.837 452.614 1.00 101.89 ? 219 ARG A N   1 
ATOM 2983 C CA  . ARG C 3 219 ? 374.766 310.208 453.515 1.00 101.89 ? 219 ARG A CA  1 
ATOM 2984 C C   . ARG C 3 219 ? 376.008 309.806 452.737 1.00 101.89 ? 219 ARG A C   1 
ATOM 2985 O O   . ARG C 3 219 ? 375.998 309.747 451.507 1.00 101.89 ? 219 ARG A O   1 
ATOM 2986 C CB  . ARG C 3 219 ? 374.177 308.981 454.212 1.00 101.89 ? 219 ARG A CB  1 
ATOM 2987 C CG  . ARG C 3 219 ? 374.067 307.774 453.324 1.00 101.89 ? 219 ARG A CG  1 
ATOM 2988 C CD  . ARG C 3 219 ? 373.367 306.641 454.026 1.00 101.89 ? 219 ARG A CD  1 
ATOM 2989 N NE  . ARG C 3 219 ? 373.308 305.456 453.183 1.00 101.89 ? 219 ARG A NE  1 
ATOM 2990 C CZ  . ARG C 3 219 ? 374.100 304.406 453.332 1.00 101.89 ? 219 ARG A CZ  1 
ATOM 2991 N NH1 . ARG C 3 219 ? 375.004 304.398 454.297 1.00 101.89 ? 219 ARG A NH1 1 
ATOM 2992 N NH2 . ARG C 3 219 ? 373.985 303.367 452.522 1.00 101.89 ? 219 ARG A NH2 1 
ATOM 2993 N N   . HIS C 3 220 ? 377.083 309.540 453.475 1.00 103.19 ? 220 HIS A N   1 
ATOM 2994 C CA  . HIS C 3 220 ? 378.290 308.973 452.894 1.00 103.19 ? 220 HIS A CA  1 
ATOM 2995 C C   . HIS C 3 220 ? 378.104 307.481 452.665 1.00 103.19 ? 220 HIS A C   1 
ATOM 2996 O O   . HIS C 3 220 ? 377.219 306.854 453.247 1.00 103.19 ? 220 HIS A O   1 
ATOM 2997 C CB  . HIS C 3 220 ? 379.492 309.175 453.812 1.00 103.19 ? 220 HIS A CB  1 
ATOM 2998 C CG  . HIS C 3 220 ? 379.870 310.604 454.032 1.00 103.19 ? 220 HIS A CG  1 
ATOM 2999 N ND1 . HIS C 3 220 ? 379.413 311.335 455.104 1.00 103.19 ? 220 HIS A ND1 1 
ATOM 3000 C CD2 . HIS C 3 220 ? 380.690 311.425 453.338 1.00 103.19 ? 220 HIS A CD2 1 
ATOM 3001 C CE1 . HIS C 3 220 ? 379.922 312.552 455.053 1.00 103.19 ? 220 HIS A CE1 1 
ATOM 3002 N NE2 . HIS C 3 220 ? 380.700 312.633 453.990 1.00 103.19 ? 220 HIS A NE2 1 
ATOM 3003 N N   . VAL C 3 221 ? 378.952 306.904 451.817 1.00 105.26 ? 221 VAL A N   1 
ATOM 3004 C CA  . VAL C 3 221 ? 378.991 305.451 451.697 1.00 105.26 ? 221 VAL A CA  1 
ATOM 3005 C C   . VAL C 3 221 ? 380.422 304.967 451.874 1.00 105.26 ? 221 VAL A C   1 
ATOM 3006 O O   . VAL C 3 221 ? 380.794 303.899 451.379 1.00 105.26 ? 221 VAL A O   1 
ATOM 3007 C CB  . VAL C 3 221 ? 378.413 304.962 450.359 1.00 105.26 ? 221 VAL A CB  1 
ATOM 3008 C CG1 . VAL C 3 221 ? 376.913 305.118 450.340 1.00 105.26 ? 221 VAL A CG1 1 
ATOM 3009 C CG2 . VAL C 3 221 ? 379.024 305.706 449.225 1.00 105.26 ? 221 VAL A CG2 1 
ATOM 3010 N N   . ASN C 3 222 ? 381.232 305.744 452.584 1.00 115.34 ? 222 ASN A N   1 
ATOM 3011 C CA  . ASN C 3 222 ? 382.589 305.351 452.932 1.00 115.34 ? 222 ASN A CA  1 
ATOM 3012 C C   . ASN C 3 222 ? 382.714 305.326 454.443 1.00 115.34 ? 222 ASN A C   1 
ATOM 3013 O O   . ASN C 3 222 ? 382.206 306.221 455.123 1.00 115.34 ? 222 ASN A O   1 
ATOM 3014 C CB  . ASN C 3 222 ? 383.623 306.309 452.346 1.00 115.34 ? 222 ASN A CB  1 
ATOM 3015 C CG  . ASN C 3 222 ? 383.864 306.075 450.882 1.00 115.34 ? 222 ASN A CG  1 
ATOM 3016 O OD1 . ASN C 3 222 ? 384.345 306.954 450.175 1.00 115.34 ? 222 ASN A OD1 1 
ATOM 3017 N ND2 . ASN C 3 222 ? 383.529 304.885 450.413 1.00 115.34 ? 222 ASN A ND2 1 
ATOM 3018 N N   . GLU C 3 223 ? 383.378 304.306 454.966 1.00 132.22 ? 223 GLU A N   1 
ATOM 3019 C CA  . GLU C 3 223 ? 383.679 304.219 456.387 1.00 132.22 ? 223 GLU A CA  1 
ATOM 3020 C C   . GLU C 3 223 ? 385.134 304.626 456.579 1.00 132.22 ? 223 GLU A C   1 
ATOM 3021 O O   . GLU C 3 223 ? 386.026 304.111 455.899 1.00 132.22 ? 223 GLU A O   1 
ATOM 3022 C CB  . GLU C 3 223 ? 383.382 302.824 456.958 1.00 132.22 ? 223 GLU A CB  1 
ATOM 3023 C CG  . GLU C 3 223 ? 384.123 301.600 456.382 1.00 132.22 ? 223 GLU A CG  1 
ATOM 3024 C CD  . GLU C 3 223 ? 383.702 301.223 454.970 1.00 132.22 ? 223 GLU A CD  1 
ATOM 3025 O OE1 . GLU C 3 223 ? 382.598 301.625 454.549 1.00 132.22 ? 223 GLU A OE1 1 
ATOM 3026 O OE2 . GLU C 3 223 ? 384.479 300.530 454.281 1.00 132.22 ? 223 GLU A OE2 1 
ATOM 3027 N N   . ALA C 3 224 ? 385.364 305.597 457.453 1.00 138.99 ? 224 ALA A N   1 
ATOM 3028 C CA  . ALA C 3 224 ? 386.692 306.157 457.650 1.00 138.99 ? 224 ALA A CA  1 
ATOM 3029 C C   . ALA C 3 224 ? 387.211 305.723 459.006 1.00 138.99 ? 224 ALA A C   1 
ATOM 3030 O O   . ALA C 3 224 ? 386.478 305.773 459.998 1.00 138.99 ? 224 ALA A O   1 
ATOM 3031 C CB  . ALA C 3 224 ? 386.674 307.682 457.549 1.00 138.99 ? 224 ALA A CB  1 
ATOM 3032 N N   . GLY C 3 225 ? 388.468 305.297 459.047 1.00 145.54 ? 225 GLY A N   1 
ATOM 3033 C CA  . GLY C 3 225 ? 389.041 304.799 460.278 1.00 145.54 ? 225 GLY A CA  1 
ATOM 3034 C C   . GLY C 3 225 ? 390.026 305.740 460.936 1.00 145.54 ? 225 GLY A C   1 
ATOM 3035 O O   . GLY C 3 225 ? 390.296 305.618 462.135 1.00 145.54 ? 225 GLY A O   1 
ATOM 3036 N N   . GLN C 3 226 ? 390.574 306.685 460.172 1.00 144.63 ? 226 GLN A N   1 
ATOM 3037 C CA  . GLN C 3 226 ? 391.667 307.491 460.704 1.00 144.63 ? 226 GLN A CA  1 
ATOM 3038 C C   . GLN C 3 226 ? 391.299 308.964 460.831 1.00 144.63 ? 226 GLN A C   1 
ATOM 3039 O O   . GLN C 3 226 ? 391.911 309.687 461.625 1.00 144.63 ? 226 GLN A O   1 
ATOM 3040 C CB  . GLN C 3 226 ? 392.913 307.311 459.840 1.00 144.63 ? 226 GLN A CB  1 
ATOM 3041 C CG  . GLN C 3 226 ? 393.606 305.965 460.026 1.00 144.63 ? 226 GLN A CG  1 
ATOM 3042 C CD  . GLN C 3 226 ? 392.938 304.838 459.259 1.00 144.63 ? 226 GLN A CD  1 
ATOM 3043 O OE1 . GLN C 3 226 ? 392.126 305.080 458.367 1.00 144.63 ? 226 GLN A OE1 1 
ATOM 3044 N NE2 . GLN C 3 226 ? 393.280 303.600 459.603 1.00 144.63 ? 226 GLN A NE2 1 
ATOM 3045 N N   . GLY C 3 227 ? 390.316 309.435 460.071 1.00 136.50 ? 227 GLY A N   1 
ATOM 3046 C CA  . GLY C 3 227 ? 389.936 310.826 460.131 1.00 136.50 ? 227 GLY A CA  1 
ATOM 3047 C C   . GLY C 3 227 ? 388.449 311.051 459.957 1.00 136.50 ? 227 GLY A C   1 
ATOM 3048 O O   . GLY C 3 227 ? 387.795 310.403 459.138 1.00 136.50 ? 227 GLY A O   1 
ATOM 3049 N N   . PRO C 3 228 ? 387.881 311.972 460.735 1.00 127.84 ? 228 PRO A N   1 
ATOM 3050 C CA  . PRO C 3 228 ? 386.477 312.346 460.531 1.00 127.84 ? 228 PRO A CA  1 
ATOM 3051 C C   . PRO C 3 228 ? 386.359 313.365 459.407 1.00 127.84 ? 228 PRO A C   1 
ATOM 3052 O O   . PRO C 3 228 ? 387.250 314.193 459.208 1.00 127.84 ? 228 PRO A O   1 
ATOM 3053 C CB  . PRO C 3 228 ? 386.067 312.953 461.879 1.00 127.84 ? 228 PRO A CB  1 
ATOM 3054 C CG  . PRO C 3 228 ? 387.229 312.711 462.808 1.00 127.84 ? 228 PRO A CG  1 
ATOM 3055 C CD  . PRO C 3 228 ? 388.431 312.598 461.942 1.00 127.84 ? 228 PRO A CD  1 
ATOM 3056 N N   . ILE C 3 229 ? 385.260 313.290 458.662 1.00 119.56 ? 229 ILE A N   1 
ATOM 3057 C CA  . ILE C 3 229 ? 384.967 314.212 457.571 1.00 119.56 ? 229 ILE A CA  1 
ATOM 3058 C C   . ILE C 3 229 ? 383.511 314.632 457.688 1.00 119.56 ? 229 ILE A C   1 
ATOM 3059 O O   . ILE C 3 229 ? 382.622 313.776 457.718 1.00 119.56 ? 229 ILE A O   1 
ATOM 3060 C CB  . ILE C 3 229 ? 385.229 313.581 456.188 1.00 119.56 ? 229 ILE A CB  1 
ATOM 3061 C CG1 . ILE C 3 229 ? 386.724 313.399 455.919 1.00 119.56 ? 229 ILE A CG1 1 
ATOM 3062 C CG2 . ILE C 3 229 ? 384.603 314.401 455.088 1.00 119.56 ? 229 ILE A CG2 1 
ATOM 3063 C CD1 . ILE C 3 229 ? 387.260 312.029 456.252 1.00 119.56 ? 229 ILE A CD1 1 
ATOM 3064 N N   . LYS C 3 230 ? 383.265 315.937 457.764 1.00 115.51 ? 230 LYS A N   1 
ATOM 3065 C CA  . LYS C 3 230 ? 381.913 316.467 457.688 1.00 115.51 ? 230 LYS A CA  1 
ATOM 3066 C C   . LYS C 3 230 ? 381.708 317.125 456.332 1.00 115.51 ? 230 LYS A C   1 
ATOM 3067 O O   . LYS C 3 230 ? 382.667 317.509 455.661 1.00 115.51 ? 230 LYS A O   1 
ATOM 3068 C CB  . LYS C 3 230 ? 381.628 317.464 458.812 1.00 115.51 ? 230 LYS A CB  1 
ATOM 3069 C CG  . LYS C 3 230 ? 382.047 318.887 458.535 1.00 115.51 ? 230 LYS A CG  1 
ATOM 3070 C CD  . LYS C 3 230 ? 381.657 319.796 459.684 1.00 115.51 ? 230 LYS A CD  1 
ATOM 3071 C CE  . LYS C 3 230 ? 380.153 319.933 459.791 1.00 115.51 ? 230 LYS A CE  1 
ATOM 3072 N NZ  . LYS C 3 230 ? 379.765 320.868 460.879 1.00 115.51 ? 230 LYS A NZ  1 
ATOM 3073 N N   . SER C 3 231 ? 380.452 317.230 455.918 1.00 108.02 ? 231 SER A N   1 
ATOM 3074 C CA  . SER C 3 231 ? 380.144 317.734 454.592 1.00 108.02 ? 231 SER A CA  1 
ATOM 3075 C C   . SER C 3 231 ? 378.855 318.533 454.629 1.00 108.02 ? 231 SER A C   1 
ATOM 3076 O O   . SER C 3 231 ? 377.928 318.207 455.369 1.00 108.02 ? 231 SER A O   1 
ATOM 3077 C CB  . SER C 3 231 ? 380.015 316.600 453.581 1.00 108.02 ? 231 SER A CB  1 
ATOM 3078 O OG  . SER C 3 231 ? 381.288 316.105 453.225 1.00 108.02 ? 231 SER A OG  1 
ATOM 3079 N N   . THR C 3 232 ? 378.807 319.580 453.819 1.00 106.60 ? 232 THR A N   1 
ATOM 3080 C CA  . THR C 3 232 ? 377.613 320.386 453.644 1.00 106.60 ? 232 THR A CA  1 
ATOM 3081 C C   . THR C 3 232 ? 376.985 320.073 452.295 1.00 106.60 ? 232 THR A C   1 
ATOM 3082 O O   . THR C 3 232 ? 377.594 319.444 451.431 1.00 106.60 ? 232 THR A O   1 
ATOM 3083 C CB  . THR C 3 232 ? 377.938 321.876 453.746 1.00 106.60 ? 232 THR A CB  1 
ATOM 3084 O OG1 . THR C 3 232 ? 378.537 322.315 452.524 1.00 106.60 ? 232 THR A OG1 1 
ATOM 3085 C CG2 . THR C 3 232 ? 378.900 322.129 454.886 1.00 106.60 ? 232 THR A CG2 1 
ATOM 3086 N N   . VAL C 3 233 ? 375.750 320.524 452.118 1.00 100.94 ? 233 VAL A N   1 
ATOM 3087 C CA  . VAL C 3 233 ? 375.019 320.277 450.881 1.00 100.94 ? 233 VAL A CA  1 
ATOM 3088 C C   . VAL C 3 233 ? 374.049 321.429 450.663 1.00 100.94 ? 233 VAL A C   1 
ATOM 3089 O O   . VAL C 3 233 ? 373.362 321.859 451.593 1.00 100.94 ? 233 VAL A O   1 
ATOM 3090 C CB  . VAL C 3 233 ? 374.317 318.901 450.918 1.00 100.94 ? 233 VAL A CB  1 
ATOM 3091 C CG1 . VAL C 3 233 ? 373.554 318.702 452.213 1.00 100.94 ? 233 VAL A CG1 1 
ATOM 3092 C CG2 . VAL C 3 233 ? 373.403 318.713 449.727 1.00 100.94 ? 233 VAL A CG2 1 
ATOM 3093 N N   . ARG C 3 234 ? 374.034 321.971 449.449 1.00 98.39  ? 234 ARG A N   1 
ATOM 3094 C CA  . ARG C 3 234 ? 373.166 323.084 449.094 1.00 98.39  ? 234 ARG A CA  1 
ATOM 3095 C C   . ARG C 3 234 ? 372.218 322.626 448.002 1.00 98.39  ? 234 ARG A C   1 
ATOM 3096 O O   . ARG C 3 234 ? 372.622 322.492 446.845 1.00 98.39  ? 234 ARG A O   1 
ATOM 3097 C CB  . ARG C 3 234 ? 373.980 324.286 448.627 1.00 98.39  ? 234 ARG A CB  1 
ATOM 3098 C CG  . ARG C 3 234 ? 375.205 324.527 449.462 1.00 98.39  ? 234 ARG A CG  1 
ATOM 3099 C CD  . ARG C 3 234 ? 376.106 325.573 448.863 1.00 98.39  ? 234 ARG A CD  1 
ATOM 3100 N NE  . ARG C 3 234 ? 377.331 325.688 449.639 1.00 98.39  ? 234 ARG A NE  1 
ATOM 3101 C CZ  . ARG C 3 234 ? 377.468 326.479 450.695 1.00 98.39  ? 234 ARG A CZ  1 
ATOM 3102 N NH1 . ARG C 3 234 ? 376.454 327.232 451.093 1.00 98.39  ? 234 ARG A NH1 1 
ATOM 3103 N NH2 . ARG C 3 234 ? 378.617 326.522 451.350 1.00 98.39  ? 234 ARG A NH2 1 
ATOM 3104 N N   . ILE C 3 235 ? 370.967 322.401 448.362 1.00 98.42  ? 235 ILE A N   1 
ATOM 3105 C CA  . ILE C 3 235 ? 369.970 321.902 447.428 1.00 98.42  ? 235 ILE A CA  1 
ATOM 3106 C C   . ILE C 3 235 ? 369.428 323.073 446.625 1.00 98.42  ? 235 ILE A C   1 
ATOM 3107 O O   . ILE C 3 235 ? 369.006 324.084 447.196 1.00 98.42  ? 235 ILE A O   1 
ATOM 3108 C CB  . ILE C 3 235 ? 368.844 321.174 448.176 1.00 98.42  ? 235 ILE A CB  1 
ATOM 3109 C CG1 . ILE C 3 235 ? 369.385 319.914 448.837 1.00 98.42  ? 235 ILE A CG1 1 
ATOM 3110 C CG2 . ILE C 3 235 ? 367.722 320.819 447.237 1.00 98.42  ? 235 ILE A CG2 1 
ATOM 3111 C CD1 . ILE C 3 235 ? 368.334 319.102 449.539 1.00 98.42  ? 235 ILE A CD1 1 
ATOM 3112 N N   . TYR C 3 236 ? 369.445 322.947 445.303 1.00 96.28  ? 236 TYR A N   1 
ATOM 3113 C CA  . TYR C 3 236 ? 368.916 323.967 444.414 1.00 96.28  ? 236 TYR A CA  1 
ATOM 3114 C C   . TYR C 3 236 ? 367.599 323.499 443.814 1.00 96.28  ? 236 TYR A C   1 
ATOM 3115 O O   . TYR C 3 236 ? 367.366 322.299 443.662 1.00 96.28  ? 236 TYR A O   1 
ATOM 3116 C CB  . TYR C 3 236 ? 369.918 324.308 443.319 1.00 96.28  ? 236 TYR A CB  1 
ATOM 3117 C CG  . TYR C 3 236 ? 370.924 325.327 443.773 1.00 96.28  ? 236 TYR A CG  1 
ATOM 3118 C CD1 . TYR C 3 236 ? 372.036 324.950 444.501 1.00 96.28  ? 236 TYR A CD1 1 
ATOM 3119 C CD2 . TYR C 3 236 ? 370.746 326.669 443.497 1.00 96.28  ? 236 TYR A CD2 1 
ATOM 3120 C CE1 . TYR C 3 236 ? 372.951 325.879 444.931 1.00 96.28  ? 236 TYR A CE1 1 
ATOM 3121 C CE2 . TYR C 3 236 ? 371.655 327.606 443.923 1.00 96.28  ? 236 TYR A CE2 1 
ATOM 3122 C CZ  . TYR C 3 236 ? 372.754 327.205 444.639 1.00 96.28  ? 236 TYR A CZ  1 
ATOM 3123 O OH  . TYR C 3 236 ? 373.664 328.141 445.064 1.00 96.28  ? 236 TYR A OH  1 
ATOM 3124 N N   . PHE C 3 237 ? 366.747 324.455 443.472 1.00 97.76  ? 237 PHE A N   1 
ATOM 3125 C CA  . PHE C 3 237 ? 365.341 324.220 443.186 1.00 97.76  ? 237 PHE A CA  1 
ATOM 3126 C C   . PHE C 3 237 ? 364.981 324.940 441.898 1.00 97.76  ? 237 PHE A C   1 
ATOM 3127 O O   . PHE C 3 237 ? 365.198 326.149 441.785 1.00 97.76  ? 237 PHE A O   1 
ATOM 3128 C CB  . PHE C 3 237 ? 364.500 324.732 444.357 1.00 97.76  ? 237 PHE A CB  1 
ATOM 3129 C CG  . PHE C 3 237 ? 363.030 324.464 444.245 1.00 97.76  ? 237 PHE A CG  1 
ATOM 3130 C CD1 . PHE C 3 237 ? 362.492 323.291 444.743 1.00 97.76  ? 237 PHE A CD1 1 
ATOM 3131 C CD2 . PHE C 3 237 ? 362.177 325.413 443.708 1.00 97.76  ? 237 PHE A CD2 1 
ATOM 3132 C CE1 . PHE C 3 237 ? 361.140 323.053 444.671 1.00 97.76  ? 237 PHE A CE1 1 
ATOM 3133 C CE2 . PHE C 3 237 ? 360.828 325.179 443.629 1.00 97.76  ? 237 PHE A CE2 1 
ATOM 3134 C CZ  . PHE C 3 237 ? 360.308 323.999 444.114 1.00 97.76  ? 237 PHE A CZ  1 
ATOM 3135 N N   . LYS C 3 238 ? 364.418 324.217 440.942 1.00 102.61 ? 238 LYS A N   1 
ATOM 3136 C CA  . LYS C 3 238 ? 364.106 324.853 439.669 1.00 102.61 ? 238 LYS A CA  1 
ATOM 3137 C C   . LYS C 3 238 ? 362.875 324.229 439.028 1.00 102.61 ? 238 LYS A C   1 
ATOM 3138 O O   . LYS C 3 238 ? 362.937 323.089 438.555 1.00 102.61 ? 238 LYS A O   1 
ATOM 3139 C CB  . LYS C 3 238 ? 365.300 324.748 438.724 1.00 102.61 ? 238 LYS A CB  1 
ATOM 3140 C CG  . LYS C 3 238 ? 365.071 325.349 437.354 1.00 102.61 ? 238 LYS A CG  1 
ATOM 3141 C CD  . LYS C 3 238 ? 366.332 325.270 436.518 1.00 102.61 ? 238 LYS A CD  1 
ATOM 3142 C CE  . LYS C 3 238 ? 366.174 326.016 435.216 1.00 102.61 ? 238 LYS A CE  1 
ATOM 3143 N NZ  . LYS C 3 238 ? 365.049 325.468 434.427 1.00 102.61 ? 238 LYS A NZ  1 
ATOM 3144 N N   . PRO C 3 239 ? 361.746 324.930 438.995 1.00 99.76  ? 239 PRO A N   1 
ATOM 3145 C CA  . PRO C 3 239 ? 360.563 324.393 438.319 1.00 99.76  ? 239 PRO A CA  1 
ATOM 3146 C C   . PRO C 3 239 ? 360.720 324.436 436.809 1.00 99.76  ? 239 PRO A C   1 
ATOM 3147 O O   . PRO C 3 239 ? 361.539 325.173 436.261 1.00 99.76  ? 239 PRO A O   1 
ATOM 3148 C CB  . PRO C 3 239 ? 359.437 325.323 438.780 1.00 99.76  ? 239 PRO A CB  1 
ATOM 3149 C CG  . PRO C 3 239 ? 359.986 326.052 439.955 1.00 99.76  ? 239 PRO A CG  1 
ATOM 3150 C CD  . PRO C 3 239 ? 361.442 326.173 439.713 1.00 99.76  ? 239 PRO A CD  1 
ATOM 3151 N N   . LYS C 3 240 ? 359.911 323.628 436.132 1.00 104.68 ? 240 LYS A N   1 
ATOM 3152 C CA  . LYS C 3 240 ? 359.933 323.557 434.679 1.00 104.68 ? 240 LYS A CA  1 
ATOM 3153 C C   . LYS C 3 240 ? 358.523 323.318 434.173 1.00 104.68 ? 240 LYS A C   1 
ATOM 3154 O O   . LYS C 3 240 ? 357.762 322.578 434.801 1.00 104.68 ? 240 LYS A O   1 
ATOM 3155 C CB  . LYS C 3 240 ? 360.839 322.432 434.181 1.00 104.68 ? 240 LYS A CB  1 
ATOM 3156 C CG  . LYS C 3 240 ? 362.313 322.761 434.124 1.00 104.68 ? 240 LYS A CG  1 
ATOM 3157 C CD  . LYS C 3 240 ? 363.097 321.612 433.508 1.00 104.68 ? 240 LYS A CD  1 
ATOM 3158 C CE  . LYS C 3 240 ? 362.786 320.292 434.194 1.00 104.68 ? 240 LYS A CE  1 
ATOM 3159 N NZ  . LYS C 3 240 ? 363.460 319.155 433.522 1.00 104.68 ? 240 LYS A NZ  1 
ATOM 3160 N N   . HIS C 3 241 ? 358.206 323.924 433.024 1.00 109.50 ? 241 HIS A N   1 
ATOM 3161 C CA  . HIS C 3 241 ? 356.905 323.827 432.353 1.00 109.50 ? 241 HIS A CA  1 
ATOM 3162 C C   . HIS C 3 241 ? 355.765 324.234 433.288 1.00 109.50 ? 241 HIS A C   1 
ATOM 3163 O O   . HIS C 3 241 ? 354.830 323.479 433.546 1.00 109.50 ? 241 HIS A O   1 
ATOM 3164 C CB  . HIS C 3 241 ? 356.678 322.424 431.780 1.00 109.50 ? 241 HIS A CB  1 
ATOM 3165 C CG  . HIS C 3 241 ? 357.792 321.943 430.906 1.00 109.50 ? 241 HIS A CG  1 
ATOM 3166 N ND1 . HIS C 3 241 ? 358.516 320.803 431.183 1.00 109.50 ? 241 HIS A ND1 1 
ATOM 3167 C CD2 . HIS C 3 241 ? 358.308 322.446 429.760 1.00 109.50 ? 241 HIS A CD2 1 
ATOM 3168 C CE1 . HIS C 3 241 ? 359.428 320.624 430.245 1.00 109.50 ? 241 HIS A CE1 1 
ATOM 3169 N NE2 . HIS C 3 241 ? 359.323 321.608 429.370 1.00 109.50 ? 241 HIS A NE2 1 
ATOM 3170 N N   . VAL C 3 242 ? 355.868 325.451 433.790 1.00 101.86 ? 242 VAL A N   1 
ATOM 3171 C CA  . VAL C 3 242 ? 354.983 325.932 434.840 1.00 101.86 ? 242 VAL A CA  1 
ATOM 3172 C C   . VAL C 3 242 ? 353.660 326.360 434.222 1.00 101.86 ? 242 VAL A C   1 
ATOM 3173 O O   . VAL C 3 242 ? 353.625 326.918 433.121 1.00 101.86 ? 242 VAL A O   1 
ATOM 3174 C CB  . VAL C 3 242 ? 355.666 327.086 435.596 1.00 101.86 ? 242 VAL A CB  1 
ATOM 3175 C CG1 . VAL C 3 242 ? 354.847 327.553 436.776 1.00 101.86 ? 242 VAL A CG1 1 
ATOM 3176 C CG2 . VAL C 3 242 ? 357.036 326.664 436.043 1.00 101.86 ? 242 VAL A CG2 1 
ATOM 3177 N N   . LYS C 3 243 ? 352.561 326.074 434.916 1.00 103.15 ? 243 LYS A N   1 
ATOM 3178 C CA  . LYS C 3 243 ? 351.245 326.587 434.567 1.00 103.15 ? 243 LYS A CA  1 
ATOM 3179 C C   . LYS C 3 243 ? 350.622 327.183 435.816 1.00 103.15 ? 243 LYS A C   1 
ATOM 3180 O O   . LYS C 3 243 ? 350.635 326.553 436.877 1.00 103.15 ? 243 LYS A O   1 
ATOM 3181 C CB  . LYS C 3 243 ? 350.348 325.488 434.003 1.00 103.15 ? 243 LYS A CB  1 
ATOM 3182 C CG  . LYS C 3 243 ? 350.770 325.004 432.645 1.00 103.15 ? 243 LYS A CG  1 
ATOM 3183 C CD  . LYS C 3 243 ? 350.280 323.602 432.387 1.00 103.15 ? 243 LYS A CD  1 
ATOM 3184 C CE  . LYS C 3 243 ? 351.009 323.001 431.208 1.00 103.15 ? 243 LYS A CE  1 
ATOM 3185 N NZ  . LYS C 3 243 ? 350.698 323.735 429.954 1.00 103.15 ? 243 LYS A NZ  1 
ATOM 3186 N N   . ALA C 3 244 ? 350.051 328.377 435.695 1.00 100.50 ? 244 ALA A N   1 
ATOM 3187 C CA  . ALA C 3 244 ? 349.446 329.048 436.841 1.00 100.50 ? 244 ALA A CA  1 
ATOM 3188 C C   . ALA C 3 244 ? 347.981 329.412 436.627 1.00 100.50 ? 244 ALA A C   1 
ATOM 3189 O O   . ALA C 3 244 ? 347.578 329.769 435.525 1.00 100.50 ? 244 ALA A O   1 
ATOM 3190 C CB  . ALA C 3 244 ? 350.247 330.282 437.212 1.00 100.50 ? 244 ALA A CB  1 
ATOM 3191 N N   . TRP C 3 245 ? 347.193 329.314 437.694 1.00 98.23  ? 245 TRP A N   1 
ATOM 3192 C CA  . TRP C 3 245 ? 345.766 329.615 437.659 1.00 98.23  ? 245 TRP A CA  1 
ATOM 3193 C C   . TRP C 3 245 ? 345.339 330.444 438.866 1.00 98.23  ? 245 TRP A C   1 
ATOM 3194 O O   . TRP C 3 245 ? 346.028 330.459 439.878 1.00 98.23  ? 245 TRP A O   1 
ATOM 3195 C CB  . TRP C 3 245 ? 344.964 328.317 437.684 1.00 98.23  ? 245 TRP A CB  1 
ATOM 3196 C CG  . TRP C 3 245 ? 345.026 327.504 436.442 1.00 98.23  ? 245 TRP A CG  1 
ATOM 3197 C CD1 . TRP C 3 245 ? 344.380 327.748 435.274 1.00 98.23  ? 245 TRP A CD1 1 
ATOM 3198 C CD2 . TRP C 3 245 ? 345.754 326.290 436.251 1.00 98.23  ? 245 TRP A CD2 1 
ATOM 3199 N NE1 . TRP C 3 245 ? 344.667 326.770 434.359 1.00 98.23  ? 245 TRP A NE1 1 
ATOM 3200 C CE2 . TRP C 3 245 ? 345.511 325.861 434.936 1.00 98.23  ? 245 TRP A CE2 1 
ATOM 3201 C CE3 . TRP C 3 245 ? 346.595 325.528 437.061 1.00 98.23  ? 245 TRP A CE3 1 
ATOM 3202 C CZ2 . TRP C 3 245 ? 346.075 324.707 434.414 1.00 98.23  ? 245 TRP A CZ2 1 
ATOM 3203 C CZ3 . TRP C 3 245 ? 347.153 324.384 436.540 1.00 98.23  ? 245 TRP A CZ3 1 
ATOM 3204 C CH2 . TRP C 3 245 ? 346.892 323.983 435.230 1.00 98.23  ? 245 TRP A CH2 1 
ATOM 3205 N N   . VAL C 3 246 ? 344.220 331.155 438.742 1.00 97.25  ? 246 VAL A N   1 
ATOM 3206 C CA  . VAL C 3 246 ? 343.657 331.932 439.856 1.00 97.25  ? 246 VAL A CA  1 
ATOM 3207 C C   . VAL C 3 246 ? 344.591 332.887 440.625 1.00 97.25  ? 246 VAL A C   1 
ATOM 3208 O O   . VAL C 3 246 ? 344.884 332.674 441.794 1.00 97.25  ? 246 VAL A O   1 
ATOM 3209 C CB  . VAL C 3 246 ? 342.737 331.079 440.772 1.00 97.25  ? 246 VAL A CB  1 
ATOM 3210 C CG1 . VAL C 3 246 ? 343.506 330.358 441.867 1.00 97.25  ? 246 VAL A CG1 1 
ATOM 3211 C CG2 . VAL C 3 246 ? 341.632 331.937 441.360 1.00 97.25  ? 246 VAL A CG2 1 
ATOM 3212 N N   . PRO C 3 247 ? 345.069 333.943 439.957 1.00 97.25  ? 247 PRO A N   1 
ATOM 3213 C CA  . PRO C 3 247 ? 345.997 334.916 440.542 1.00 97.25  ? 247 PRO A CA  1 
ATOM 3214 C C   . PRO C 3 247 ? 345.431 335.599 441.783 1.00 97.25  ? 247 PRO A C   1 
ATOM 3215 O O   . PRO C 3 247 ? 344.239 335.876 441.850 1.00 97.25  ? 247 PRO A O   1 
ATOM 3216 C CB  . PRO C 3 247 ? 346.151 335.947 439.428 1.00 97.25  ? 247 PRO A CB  1 
ATOM 3217 C CG  . PRO C 3 247 ? 344.874 335.857 438.670 1.00 97.25  ? 247 PRO A CG  1 
ATOM 3218 C CD  . PRO C 3 247 ? 344.562 334.393 438.653 1.00 97.25  ? 247 PRO A CD  1 
ATOM 3219 N N   . ARG C 3 248 ? 346.306 335.861 442.751 1.00 101.77 ? 248 ARG A N   1 
ATOM 3220 C CA  . ARG C 3 248 ? 345.955 336.455 444.039 1.00 101.77 ? 248 ARG A CA  1 
ATOM 3221 C C   . ARG C 3 248 ? 346.848 337.656 444.375 1.00 101.77 ? 248 ARG A C   1 
ATOM 3222 O O   . ARG C 3 248 ? 347.942 337.776 443.842 1.00 101.77 ? 248 ARG A O   1 
ATOM 3223 C CB  . ARG C 3 248 ? 346.128 335.379 445.110 1.00 101.77 ? 248 ARG A CB  1 
ATOM 3224 C CG  . ARG C 3 248 ? 345.512 335.671 446.464 1.00 101.77 ? 248 ARG A CG  1 
ATOM 3225 C CD  . ARG C 3 248 ? 345.728 334.492 447.391 1.00 101.77 ? 248 ARG A CD  1 
ATOM 3226 N NE  . ARG C 3 248 ? 345.621 333.237 446.660 1.00 101.77 ? 248 ARG A NE  1 
ATOM 3227 C CZ  . ARG C 3 248 ? 344.616 332.383 446.796 1.00 101.77 ? 248 ARG A CZ  1 
ATOM 3228 N NH1 . ARG C 3 248 ? 343.633 332.647 447.644 1.00 101.77 ? 248 ARG A NH1 1 
ATOM 3229 N NH2 . ARG C 3 248 ? 344.595 331.265 446.085 1.00 101.77 ? 248 ARG A NH2 1 
ATOM 3230 N N   . PRO C 3 249 ? 346.375 338.555 445.255 1.00 98.53  ? 249 PRO A N   1 
ATOM 3231 C CA  . PRO C 3 249 ? 347.097 339.754 445.701 1.00 98.53  ? 249 PRO A CA  1 
ATOM 3232 C C   . PRO C 3 249 ? 348.344 339.369 446.478 1.00 98.53  ? 249 PRO A C   1 
ATOM 3233 O O   . PRO C 3 249 ? 348.315 338.368 447.181 1.00 98.53  ? 249 PRO A O   1 
ATOM 3234 C CB  . PRO C 3 249 ? 346.111 340.431 446.659 1.00 98.53  ? 249 PRO A CB  1 
ATOM 3235 C CG  . PRO C 3 249 ? 344.804 339.752 446.456 1.00 98.53  ? 249 PRO A CG  1 
ATOM 3236 C CD  . PRO C 3 249 ? 345.123 338.367 445.998 1.00 98.53  ? 249 PRO A CD  1 
ATOM 3237 N N   . PRO C 3 250 ? 349.427 340.148 446.361 1.00 103.13 ? 250 PRO A N   1 
ATOM 3238 C CA  . PRO C 3 250 ? 350.653 339.800 447.083 1.00 103.13 ? 250 PRO A CA  1 
ATOM 3239 C C   . PRO C 3 250 ? 350.530 340.064 448.571 1.00 103.13 ? 250 PRO A C   1 
ATOM 3240 O O   . PRO C 3 250 ? 349.827 340.975 449.010 1.00 103.13 ? 250 PRO A O   1 
ATOM 3241 C CB  . PRO C 3 250 ? 351.709 340.719 446.457 1.00 103.13 ? 250 PRO A CB  1 
ATOM 3242 C CG  . PRO C 3 250 ? 351.069 341.307 445.252 1.00 103.13 ? 250 PRO A CG  1 
ATOM 3243 C CD  . PRO C 3 250 ? 349.621 341.352 445.544 1.00 103.13 ? 250 PRO A CD  1 
ATOM 3244 N N   . ARG C 3 251 ? 351.249 339.258 449.344 1.00 104.51 ? 251 ARG A N   1 
ATOM 3245 C CA  . ARG C 3 251 ? 351.162 339.329 450.795 1.00 104.51 ? 251 ARG A CA  1 
ATOM 3246 C C   . ARG C 3 251 ? 351.860 340.568 451.328 1.00 104.51 ? 251 ARG A C   1 
ATOM 3247 O O   . ARG C 3 251 ? 353.000 340.860 450.961 1.00 104.51 ? 251 ARG A O   1 
ATOM 3248 C CB  . ARG C 3 251 ? 351.776 338.084 451.413 1.00 104.51 ? 251 ARG A CB  1 
ATOM 3249 C CG  . ARG C 3 251 ? 351.714 338.066 452.914 1.00 104.51 ? 251 ARG A CG  1 
ATOM 3250 C CD  . ARG C 3 251 ? 352.222 336.761 453.423 1.00 104.51 ? 251 ARG A CD  1 
ATOM 3251 N NE  . ARG C 3 251 ? 352.306 336.719 454.872 1.00 104.51 ? 251 ARG A NE  1 
ATOM 3252 C CZ  . ARG C 3 251 ? 351.349 336.241 455.650 1.00 104.51 ? 251 ARG A CZ  1 
ATOM 3253 N NH1 . ARG C 3 251 ? 350.240 335.771 455.110 1.00 104.51 ? 251 ARG A NH1 1 
ATOM 3254 N NH2 . ARG C 3 251 ? 351.503 336.230 456.961 1.00 104.51 ? 251 ARG A NH2 1 
ATOM 3255 N N   . LEU C 3 252 ? 351.174 341.289 452.210 1.00 104.84 ? 252 LEU A N   1 
ATOM 3256 C CA  . LEU C 3 252 ? 351.674 342.516 452.814 1.00 104.84 ? 252 LEU A CA  1 
ATOM 3257 C C   . LEU C 3 252 ? 352.435 342.267 454.109 1.00 104.84 ? 252 LEU A C   1 
ATOM 3258 O O   . LEU C 3 252 ? 353.523 342.814 454.302 1.00 104.84 ? 252 LEU A O   1 
ATOM 3259 C CB  . LEU C 3 252 ? 350.505 343.471 453.069 1.00 104.84 ? 252 LEU A CB  1 
ATOM 3260 C CG  . LEU C 3 252 ? 350.737 344.639 454.018 1.00 104.84 ? 252 LEU A CG  1 
ATOM 3261 C CD1 . LEU C 3 252 ? 351.562 345.699 453.340 1.00 104.84 ? 252 LEU A CD1 1 
ATOM 3262 C CD2 . LEU C 3 252 ? 349.417 345.209 454.470 1.00 104.84 ? 252 LEU A CD2 1 
ATOM 3263 N N   . CYS C 3 253 ? 351.885 341.450 455.000 1.00 109.48 ? 253 CYS A N   1 
ATOM 3264 C CA  . CYS C 3 253 ? 352.500 341.207 456.294 1.00 109.48 ? 253 CYS A CA  1 
ATOM 3265 C C   . CYS C 3 253 ? 353.708 340.283 456.156 1.00 109.48 ? 253 CYS A C   1 
ATOM 3266 O O   . CYS C 3 253 ? 353.913 339.630 455.131 1.00 109.48 ? 253 CYS A O   1 
ATOM 3267 C CB  . CYS C 3 253 ? 351.486 340.594 457.254 1.00 109.48 ? 253 CYS A CB  1 
ATOM 3268 S SG  . CYS C 3 253 ? 350.071 341.645 457.593 1.00 109.48 ? 253 CYS A SG  1 
ATOM 3269 N N   . GLN C 3 254 ? 354.513 340.236 457.210 1.00 115.52 ? 254 GLN A N   1 
ATOM 3270 C CA  . GLN C 3 254 ? 355.686 339.379 457.219 1.00 115.52 ? 254 GLN A CA  1 
ATOM 3271 C C   . GLN C 3 254 ? 355.287 337.937 457.483 1.00 115.52 ? 254 GLN A C   1 
ATOM 3272 O O   . GLN C 3 254 ? 354.210 337.655 458.011 1.00 115.52 ? 254 GLN A O   1 
ATOM 3273 C CB  . GLN C 3 254 ? 356.681 339.840 458.279 1.00 115.52 ? 254 GLN A CB  1 
ATOM 3274 C CG  . GLN C 3 254 ? 357.255 341.219 458.027 1.00 115.52 ? 254 GLN A CG  1 
ATOM 3275 C CD  . GLN C 3 254 ? 358.514 341.179 457.190 1.00 115.52 ? 254 GLN A CD  1 
ATOM 3276 O OE1 . GLN C 3 254 ? 359.110 340.121 456.997 1.00 115.52 ? 254 GLN A OE1 1 
ATOM 3277 N NE2 . GLN C 3 254 ? 358.926 342.335 456.685 1.00 115.52 ? 254 GLN A NE2 1 
ATOM 3278 N N   . TYR C 3 255 ? 356.169 337.019 457.105 1.00 113.86 ? 255 TYR A N   1 
ATOM 3279 C CA  . TYR C 3 255 ? 355.930 335.604 457.332 1.00 113.86 ? 255 TYR A CA  1 
ATOM 3280 C C   . TYR C 3 255 ? 356.329 335.224 458.747 1.00 113.86 ? 255 TYR A C   1 
ATOM 3281 O O   . TYR C 3 255 ? 357.453 335.486 459.180 1.00 113.86 ? 255 TYR A O   1 
ATOM 3282 C CB  . TYR C 3 255 ? 356.714 334.766 456.330 1.00 113.86 ? 255 TYR A CB  1 
ATOM 3283 C CG  . TYR C 3 255 ? 356.105 334.774 454.961 1.00 113.86 ? 255 TYR A CG  1 
ATOM 3284 C CD1 . TYR C 3 255 ? 354.994 334.001 454.679 1.00 113.86 ? 255 TYR A CD1 1 
ATOM 3285 C CD2 . TYR C 3 255 ? 356.629 335.567 453.952 1.00 113.86 ? 255 TYR A CD2 1 
ATOM 3286 C CE1 . TYR C 3 255 ? 354.430 334.001 453.428 1.00 113.86 ? 255 TYR A CE1 1 
ATOM 3287 C CE2 . TYR C 3 255 ? 356.066 335.580 452.696 1.00 113.86 ? 255 TYR A CE2 1 
ATOM 3288 C CZ  . TYR C 3 255 ? 354.967 334.796 452.442 1.00 113.86 ? 255 TYR A CZ  1 
ATOM 3289 O OH  . TYR C 3 255 ? 354.399 334.804 451.195 1.00 113.86 ? 255 TYR A OH  1 
ATOM 3290 N N   . GLU C 3 256 ? 355.407 334.594 459.464 1.00 117.57 ? 256 GLU A N   1 
ATOM 3291 C CA  . GLU C 3 256 ? 355.650 334.236 460.854 1.00 117.57 ? 256 GLU A CA  1 
ATOM 3292 C C   . GLU C 3 256 ? 355.996 332.769 461.029 1.00 117.57 ? 256 GLU A C   1 
ATOM 3293 O O   . GLU C 3 256 ? 357.012 332.448 461.655 1.00 117.57 ? 256 GLU A O   1 
ATOM 3294 C CB  . GLU C 3 256 ? 354.429 334.594 461.709 1.00 117.57 ? 256 GLU A CB  1 
ATOM 3295 C CG  . GLU C 3 256 ? 354.108 336.070 461.704 1.00 117.57 ? 256 GLU A CG  1 
ATOM 3296 C CD  . GLU C 3 256 ? 354.832 336.829 462.796 1.00 117.57 ? 256 GLU A CD  1 
ATOM 3297 O OE1 . GLU C 3 256 ? 354.613 338.052 462.916 1.00 117.57 ? 256 GLU A OE1 1 
ATOM 3298 O OE2 . GLU C 3 256 ? 355.616 336.206 463.539 1.00 117.57 ? 256 GLU A OE2 1 
ATOM 3299 N N   . LYS C 3 257 ? 355.187 331.865 460.493 1.00 119.98 ? 257 LYS A N   1 
ATOM 3300 C CA  . LYS C 3 257 ? 355.439 330.442 460.621 1.00 119.98 ? 257 LYS A CA  1 
ATOM 3301 C C   . LYS C 3 257 ? 355.497 329.801 459.244 1.00 119.98 ? 257 LYS A C   1 
ATOM 3302 O O   . LYS C 3 257 ? 355.189 330.425 458.227 1.00 119.98 ? 257 LYS A O   1 
ATOM 3303 C CB  . LYS C 3 257 ? 354.367 329.764 461.475 1.00 119.98 ? 257 LYS A CB  1 
ATOM 3304 C CG  . LYS C 3 257 ? 354.364 330.217 462.917 1.00 119.98 ? 257 LYS A CG  1 
ATOM 3305 C CD  . LYS C 3 257 ? 354.611 329.061 463.862 1.00 119.98 ? 257 LYS A CD  1 
ATOM 3306 C CE  . LYS C 3 257 ? 354.969 329.569 465.247 1.00 119.98 ? 257 LYS A CE  1 
ATOM 3307 N NZ  . LYS C 3 257 ? 355.175 328.459 466.215 1.00 119.98 ? 257 LYS A NZ  1 
ATOM 3308 N N   . GLN C 3 258 ? 355.901 328.536 459.225 1.00 120.34 ? 258 GLN A N   1 
ATOM 3309 C CA  . GLN C 3 258 ? 356.083 327.812 457.978 1.00 120.34 ? 258 GLN A CA  1 
ATOM 3310 C C   . GLN C 3 258 ? 354.836 327.065 457.543 1.00 120.34 ? 258 GLN A C   1 
ATOM 3311 O O   . GLN C 3 258 ? 354.586 326.935 456.342 1.00 120.34 ? 258 GLN A O   1 
ATOM 3312 C CB  . GLN C 3 258 ? 357.241 326.825 458.122 1.00 120.34 ? 258 GLN A CB  1 
ATOM 3313 C CG  . GLN C 3 258 ? 357.777 326.283 456.821 1.00 120.34 ? 258 GLN A CG  1 
ATOM 3314 C CD  . GLN C 3 258 ? 359.013 325.440 457.025 1.00 120.34 ? 258 GLN A CD  1 
ATOM 3315 O OE1 . GLN C 3 258 ? 358.932 324.217 457.133 1.00 120.34 ? 258 GLN A OE1 1 
ATOM 3316 N NE2 . GLN C 3 258 ? 360.167 326.090 457.091 1.00 120.34 ? 258 GLN A NE2 1 
ATOM 3317 N N   . LYS C 3 259 ? 354.042 326.583 458.492 1.00 124.23 ? 259 LYS A N   1 
ATOM 3318 C CA  . LYS C 3 259 ? 352.937 325.694 458.158 1.00 124.23 ? 259 LYS A CA  1 
ATOM 3319 C C   . LYS C 3 259 ? 351.708 326.471 457.707 1.00 124.23 ? 259 LYS A C   1 
ATOM 3320 O O   . LYS C 3 259 ? 351.045 326.091 456.737 1.00 124.23 ? 259 LYS A O   1 
ATOM 3321 C CB  . LYS C 3 259 ? 352.582 324.811 459.358 1.00 124.23 ? 259 LYS A CB  1 
ATOM 3322 C CG  . LYS C 3 259 ? 353.500 323.611 459.612 1.00 124.23 ? 259 LYS A CG  1 
ATOM 3323 C CD  . LYS C 3 259 ? 354.770 323.990 460.371 1.00 124.23 ? 259 LYS A CD  1 
ATOM 3324 C CE  . LYS C 3 259 ? 354.449 324.764 461.640 1.00 124.23 ? 259 LYS A CE  1 
ATOM 3325 N NZ  . LYS C 3 259 ? 355.672 325.325 462.274 1.00 124.23 ? 259 LYS A NZ  1 
ATOM 3326 N N   . ASN C 3 260 ? 351.389 327.556 458.396 1.00 122.69 ? 260 ASN A N   1 
ATOM 3327 C CA  . ASN C 3 260 ? 350.113 328.234 458.245 1.00 122.69 ? 260 ASN A CA  1 
ATOM 3328 C C   . ASN C 3 260 ? 350.317 329.680 457.809 1.00 122.69 ? 260 ASN A C   1 
ATOM 3329 O O   . ASN C 3 260 ? 351.427 330.119 457.510 1.00 122.69 ? 260 ASN A O   1 
ATOM 3330 C CB  . ASN C 3 260 ? 349.319 328.156 459.548 1.00 122.69 ? 260 ASN A CB  1 
ATOM 3331 C CG  . ASN C 3 260 ? 350.181 328.413 460.760 1.00 122.69 ? 260 ASN A CG  1 
ATOM 3332 O OD1 . ASN C 3 260 ? 351.360 328.722 460.635 1.00 122.69 ? 260 ASN A OD1 1 
ATOM 3333 N ND2 . ASN C 3 260 ? 349.599 328.279 461.943 1.00 122.69 ? 260 ASN A ND2 1 
ATOM 3334 N N   . VAL C 3 261 ? 349.213 330.417 457.780 1.00 120.57 ? 261 VAL A N   1 
ATOM 3335 C CA  . VAL C 3 261 ? 349.163 331.762 457.232 1.00 120.57 ? 261 VAL A CA  1 
ATOM 3336 C C   . VAL C 3 261 ? 349.009 332.780 458.368 1.00 120.57 ? 261 VAL A C   1 
ATOM 3337 O O   . VAL C 3 261 ? 348.312 333.783 458.240 1.00 120.57 ? 261 VAL A O   1 
ATOM 3338 C CB  . VAL C 3 261 ? 348.039 331.867 456.178 1.00 120.57 ? 261 VAL A CB  1 
ATOM 3339 C CG1 . VAL C 3 261 ? 348.216 333.054 455.207 1.00 120.57 ? 261 VAL A CG1 1 
ATOM 3340 C CG2 . VAL C 3 261 ? 347.909 330.572 455.403 1.00 120.57 ? 261 VAL A CG2 1 
ATOM 3341 N N   . ASN C 3 262 ? 349.604 332.490 459.520 1.00 119.84 ? 262 ASN A N   1 
ATOM 3342 C CA  . ASN C 3 262 ? 349.457 333.368 460.667 1.00 119.84 ? 262 ASN A CA  1 
ATOM 3343 C C   . ASN C 3 262 ? 350.265 334.643 460.469 1.00 119.84 ? 262 ASN A C   1 
ATOM 3344 O O   . ASN C 3 262 ? 351.282 334.664 459.774 1.00 119.84 ? 262 ASN A O   1 
ATOM 3345 C CB  . ASN C 3 262 ? 349.897 332.660 461.942 1.00 119.84 ? 262 ASN A CB  1 
ATOM 3346 C CG  . ASN C 3 262 ? 348.857 331.698 462.452 1.00 119.84 ? 262 ASN A CG  1 
ATOM 3347 O OD1 . ASN C 3 262 ? 347.740 331.656 461.947 1.00 119.84 ? 262 ASN A OD1 1 
ATOM 3348 N ND2 . ASN C 3 262 ? 349.217 330.916 463.458 1.00 119.84 ? 262 ASN A ND2 1 
ATOM 3349 N N   . PHE C 3 263 ? 349.793 335.719 461.090 1.00 108.13 ? 263 PHE A N   1 
ATOM 3350 C CA  . PHE C 3 263 ? 350.415 337.023 460.921 1.00 108.13 ? 263 PHE A CA  1 
ATOM 3351 C C   . PHE C 3 263 ? 350.045 337.908 462.102 1.00 108.13 ? 263 PHE A C   1 
ATOM 3352 O O   . PHE C 3 263 ? 349.221 337.549 462.946 1.00 108.13 ? 263 PHE A O   1 
ATOM 3353 C CB  . PHE C 3 263 ? 350.004 337.672 459.594 1.00 108.13 ? 263 PHE A CB  1 
ATOM 3354 C CG  . PHE C 3 263 ? 348.536 337.976 459.479 1.00 108.13 ? 263 PHE A CG  1 
ATOM 3355 C CD1 . PHE C 3 263 ? 347.644 337.004 459.067 1.00 108.13 ? 263 PHE A CD1 1 
ATOM 3356 C CD2 . PHE C 3 263 ? 348.055 339.246 459.737 1.00 108.13 ? 263 PHE A CD2 1 
ATOM 3357 C CE1 . PHE C 3 263 ? 346.302 337.285 458.949 1.00 108.13 ? 263 PHE A CE1 1 
ATOM 3358 C CE2 . PHE C 3 263 ? 346.712 339.530 459.622 1.00 108.13 ? 263 PHE A CE2 1 
ATOM 3359 C CZ  . PHE C 3 263 ? 345.838 338.549 459.225 1.00 108.13 ? 263 PHE A CZ  1 
ATOM 3360 N N   . SER C 3 264 ? 350.677 339.074 462.151 1.00 107.25 ? 264 SER A N   1 
ATOM 3361 C CA  . SER C 3 264 ? 350.314 340.185 463.001 1.00 107.25 ? 264 SER A CA  1 
ATOM 3362 C C   . SER C 3 264 ? 349.997 341.386 462.122 1.00 107.25 ? 264 SER A C   1 
ATOM 3363 O O   . SER C 3 264 ? 350.721 341.640 461.155 1.00 107.25 ? 264 SER A O   1 
ATOM 3364 C CB  . SER C 3 264 ? 351.444 340.536 463.967 1.00 107.25 ? 264 SER A CB  1 
ATOM 3365 O OG  . SER C 3 264 ? 352.686 340.533 463.291 1.00 107.25 ? 264 SER A OG  1 
ATOM 3366 N N   . PRO C 3 265 ? 348.925 342.124 462.410 1.00 105.42 ? 265 PRO A N   1 
ATOM 3367 C CA  . PRO C 3 265 ? 348.456 343.148 461.467 1.00 105.42 ? 265 PRO A CA  1 
ATOM 3368 C C   . PRO C 3 265 ? 349.386 344.350 461.428 1.00 105.42 ? 265 PRO A C   1 
ATOM 3369 O O   . PRO C 3 265 ? 349.820 344.854 462.464 1.00 105.42 ? 265 PRO A O   1 
ATOM 3370 C CB  . PRO C 3 265 ? 347.075 343.526 462.014 1.00 105.42 ? 265 PRO A CB  1 
ATOM 3371 C CG  . PRO C 3 265 ? 346.713 342.428 462.948 1.00 105.42 ? 265 PRO A CG  1 
ATOM 3372 C CD  . PRO C 3 265 ? 347.996 341.966 463.534 1.00 105.42 ? 265 PRO A CD  1 
ATOM 3373 N N   . ILE C 3 266 ? 349.692 344.799 460.215 1.00 107.52 ? 266 ILE A N   1 
ATOM 3374 C CA  . ILE C 3 266 ? 350.568 345.937 459.989 1.00 107.52 ? 266 ILE A CA  1 
ATOM 3375 C C   . ILE C 3 266 ? 349.824 346.934 459.109 1.00 107.52 ? 266 ILE A C   1 
ATOM 3376 O O   . ILE C 3 266 ? 348.812 346.608 458.485 1.00 107.52 ? 266 ILE A O   1 
ATOM 3377 C CB  . ILE C 3 266 ? 351.914 345.500 459.363 1.00 107.52 ? 266 ILE A CB  1 
ATOM 3378 C CG1 . ILE C 3 266 ? 353.052 346.428 459.796 1.00 107.52 ? 266 ILE A CG1 1 
ATOM 3379 C CG2 . ILE C 3 266 ? 351.825 345.404 457.852 1.00 107.52 ? 266 ILE A CG2 1 
ATOM 3380 C CD1 . ILE C 3 266 ? 353.292 346.438 461.287 1.00 107.52 ? 266 ILE A CD1 1 
ATOM 3381 N N   . GLY C 3 267 ? 350.314 348.173 459.096 1.00 111.46 ? 267 GLY A N   1 
ATOM 3382 C CA  . GLY C 3 267 ? 349.710 349.215 458.292 1.00 111.46 ? 267 GLY A CA  1 
ATOM 3383 C C   . GLY C 3 267 ? 349.859 348.960 456.805 1.00 111.46 ? 267 GLY A C   1 
ATOM 3384 O O   . GLY C 3 267 ? 350.672 348.157 456.351 1.00 111.46 ? 267 GLY A O   1 
ATOM 3385 N N   . VAL C 3 268 ? 349.052 349.677 456.025 1.00 111.95 ? 268 VAL A N   1 
ATOM 3386 C CA  . VAL C 3 268 ? 348.926 349.356 454.608 1.00 111.95 ? 268 VAL A CA  1 
ATOM 3387 C C   . VAL C 3 268 ? 350.100 349.920 453.817 1.00 111.95 ? 268 VAL A C   1 
ATOM 3388 O O   . VAL C 3 268 ? 350.706 349.222 452.997 1.00 111.95 ? 268 VAL A O   1 
ATOM 3389 C CB  . VAL C 3 268 ? 347.581 349.861 454.063 1.00 111.95 ? 268 VAL A CB  1 
ATOM 3390 C CG1 . VAL C 3 268 ? 347.412 349.439 452.624 1.00 111.95 ? 268 VAL A CG1 1 
ATOM 3391 C CG2 . VAL C 3 268 ? 346.451 349.317 454.896 1.00 111.95 ? 268 VAL A CG2 1 
ATOM 3392 N N   . THR C 3 269 ? 350.436 351.185 454.038 1.00 117.01 ? 269 THR A N   1 
ATOM 3393 C CA  . THR C 3 269 ? 351.512 351.830 453.299 1.00 117.01 ? 269 THR A CA  1 
ATOM 3394 C C   . THR C 3 269 ? 352.289 352.679 454.300 1.00 117.01 ? 269 THR A C   1 
ATOM 3395 O O   . THR C 3 269 ? 351.748 353.092 455.328 1.00 117.01 ? 269 THR A O   1 
ATOM 3396 C CB  . THR C 3 269 ? 350.919 352.625 452.119 1.00 117.01 ? 269 THR A CB  1 
ATOM 3397 O OG1 . THR C 3 269 ? 350.179 351.732 451.280 1.00 117.01 ? 269 THR A OG1 1 
ATOM 3398 C CG2 . THR C 3 269 ? 351.985 353.269 451.237 1.00 117.01 ? 269 THR A CG2 1 
ATOM 3399 N N   . THR C 3 270 ? 353.579 352.885 454.033 1.00 115.17 ? 270 THR A N   1 
ATOM 3400 C CA  . THR C 3 270 ? 354.381 353.787 454.847 1.00 115.17 ? 270 THR A CA  1 
ATOM 3401 C C   . THR C 3 270 ? 353.838 355.212 454.766 1.00 115.17 ? 270 THR A C   1 
ATOM 3402 O O   . THR C 3 270 ? 353.372 355.665 453.718 1.00 115.17 ? 270 THR A O   1 
ATOM 3403 C CB  . THR C 3 270 ? 355.850 353.727 454.420 1.00 115.17 ? 270 THR A CB  1 
ATOM 3404 O OG1 . THR C 3 270 ? 356.617 354.661 455.190 1.00 115.17 ? 270 THR A OG1 1 
ATOM 3405 C CG2 . THR C 3 270 ? 356.026 354.002 452.934 1.00 115.17 ? 270 THR A CG2 1 
ATOM 3406 N N   . SER C 3 271 ? 353.847 355.894 455.901 1.00 113.31 ? 271 SER A N   1 
ATOM 3407 C CA  . SER C 3 271 ? 353.079 357.114 456.072 1.00 113.31 ? 271 SER A CA  1 
ATOM 3408 C C   . SER C 3 271 ? 353.875 358.351 455.682 1.00 113.31 ? 271 SER A C   1 
ATOM 3409 O O   . SER C 3 271 ? 355.103 358.383 455.758 1.00 113.31 ? 271 SER A O   1 
ATOM 3410 C CB  . SER C 3 271 ? 352.626 357.242 457.516 1.00 113.31 ? 271 SER A CB  1 
ATOM 3411 O OG  . SER C 3 271 ? 353.644 357.831 458.298 1.00 113.31 ? 271 SER A OG  1 
ATOM 3412 N N   . ARG C 3 272 ? 353.147 359.384 455.271 1.00 111.74 ? 272 ARG A N   1 
ATOM 3413 C CA  . ARG C 3 272 ? 353.696 360.704 455.001 1.00 111.74 ? 272 ARG A CA  1 
ATOM 3414 C C   . ARG C 3 272 ? 353.078 361.707 455.968 1.00 111.74 ? 272 ARG A C   1 
ATOM 3415 O O   . ARG C 3 272 ? 352.246 361.360 456.805 1.00 111.74 ? 272 ARG A O   1 
ATOM 3416 C CB  . ARG C 3 272 ? 353.452 361.113 453.550 1.00 111.74 ? 272 ARG A CB  1 
ATOM 3417 C CG  . ARG C 3 272 ? 351.998 361.204 453.168 1.00 111.74 ? 272 ARG A CG  1 
ATOM 3418 C CD  . ARG C 3 272 ? 351.868 361.589 451.711 1.00 111.74 ? 272 ARG A CD  1 
ATOM 3419 N NE  . ARG C 3 272 ? 350.480 361.704 451.288 1.00 111.74 ? 272 ARG A NE  1 
ATOM 3420 C CZ  . ARG C 3 272 ? 350.106 362.187 450.112 1.00 111.74 ? 272 ARG A CZ  1 
ATOM 3421 N NH1 . ARG C 3 272 ? 351.017 362.599 449.249 1.00 111.74 ? 272 ARG A NH1 1 
ATOM 3422 N NH2 . ARG C 3 272 ? 348.824 362.259 449.800 1.00 111.74 ? 272 ARG A NH2 1 
ATOM 3423 N N   . THR C 3 273 ? 353.489 362.966 455.846 1.00 119.18 ? 273 THR A N   1 
ATOM 3424 C CA  . THR C 3 273 ? 353.107 363.975 456.827 1.00 119.18 ? 273 THR A CA  1 
ATOM 3425 C C   . THR C 3 273 ? 351.672 364.454 456.672 1.00 119.18 ? 273 THR A C   1 
ATOM 3426 O O   . THR C 3 273 ? 350.962 364.586 457.675 1.00 119.18 ? 273 THR A O   1 
ATOM 3427 C CB  . THR C 3 273 ? 354.046 365.178 456.741 1.00 119.18 ? 273 THR A CB  1 
ATOM 3428 O OG1 . THR C 3 273 ? 355.395 364.721 456.596 1.00 119.18 ? 273 THR A OG1 1 
ATOM 3429 C CG2 . THR C 3 273 ? 353.943 366.020 458.000 1.00 119.18 ? 273 THR A CG2 1 
ATOM 3430 N N   . ASP C 3 274 ? 351.225 364.716 455.448 1.00 119.25 ? 274 ASP A N   1 
ATOM 3431 C CA  . ASP C 3 274 ? 349.883 365.228 455.223 1.00 119.25 ? 274 ASP A CA  1 
ATOM 3432 C C   . ASP C 3 274 ? 349.360 364.725 453.886 1.00 119.25 ? 274 ASP A C   1 
ATOM 3433 O O   . ASP C 3 274 ? 350.053 364.015 453.155 1.00 119.25 ? 274 ASP A O   1 
ATOM 3434 C CB  . ASP C 3 274 ? 349.861 366.757 455.291 1.00 119.25 ? 274 ASP A CB  1 
ATOM 3435 C CG  . ASP C 3 274 ? 350.907 367.399 454.399 1.00 119.25 ? 274 ASP A CG  1 
ATOM 3436 O OD1 . ASP C 3 274 ? 351.719 366.672 453.789 1.00 119.25 ? 274 ASP A OD1 1 
ATOM 3437 O OD2 . ASP C 3 274 ? 350.923 368.645 454.314 1.00 119.25 ? 274 ASP A OD2 1 
ATOM 3438 N N   . ILE C 3 275 ? 348.119 365.098 453.575 1.00 113.66 ? 275 ILE A N   1 
ATOM 3439 C CA  . ILE C 3 275 ? 347.512 364.625 452.337 1.00 113.66 ? 275 ILE A CA  1 
ATOM 3440 C C   . ILE C 3 275 ? 348.010 365.442 451.147 1.00 113.66 ? 275 ILE A C   1 
ATOM 3441 O O   . ILE C 3 275 ? 348.200 364.902 450.050 1.00 113.66 ? 275 ILE A O   1 
ATOM 3442 C CB  . ILE C 3 275 ? 345.976 364.633 452.479 1.00 113.66 ? 275 ILE A CB  1 
ATOM 3443 C CG1 . ILE C 3 275 ? 345.286 364.203 451.187 1.00 113.66 ? 275 ILE A CG1 1 
ATOM 3444 C CG2 . ILE C 3 275 ? 345.469 365.984 452.962 1.00 113.66 ? 275 ILE A CG2 1 
ATOM 3445 C CD1 . ILE C 3 275 ? 343.795 364.123 451.303 1.00 113.66 ? 275 ILE A CD1 1 
ATOM 3446 N N   . ILE C 3 276 ? 348.285 366.726 451.344 1.00 115.00 ? 276 ILE A N   1 
ATOM 3447 C CA  . ILE C 3 276 ? 348.808 367.557 450.271 1.00 115.00 ? 276 ILE A CA  1 
ATOM 3448 C C   . ILE C 3 276 ? 350.327 367.476 450.247 1.00 115.00 ? 276 ILE A C   1 
ATOM 3449 O O   . ILE C 3 276 ? 350.952 367.668 449.205 1.00 115.00 ? 276 ILE A O   1 
ATOM 3450 C CB  . ILE C 3 276 ? 348.341 369.008 450.413 1.00 115.00 ? 276 ILE A CB  1 
ATOM 3451 C CG1 . ILE C 3 276 ? 349.191 369.741 451.448 1.00 115.00 ? 276 ILE A CG1 1 
ATOM 3452 C CG2 . ILE C 3 276 ? 346.884 369.053 450.813 1.00 115.00 ? 276 ILE A CG2 1 
ATOM 3453 C CD1 . ILE C 3 276 ? 348.812 371.187 451.629 1.00 115.00 ? 276 ILE A CD1 1 
ATOM 3454 N N   . ARG D 4 14  ? 313.824 340.938 434.567 1.00 127.75 ? 14  ARG B N   1 
ATOM 3455 C CA  . ARG D 4 14  ? 312.814 341.240 435.572 1.00 127.75 ? 14  ARG B CA  1 
ATOM 3456 C C   . ARG D 4 14  ? 311.947 340.027 435.861 1.00 127.75 ? 14  ARG B C   1 
ATOM 3457 O O   . ARG D 4 14  ? 311.472 339.371 434.932 1.00 127.75 ? 14  ARG B O   1 
ATOM 3458 C CB  . ARG D 4 14  ? 311.934 342.400 435.120 1.00 127.75 ? 14  ARG B CB  1 
ATOM 3459 C CG  . ARG D 4 14  ? 312.695 343.630 434.702 1.00 127.75 ? 14  ARG B CG  1 
ATOM 3460 C CD  . ARG D 4 14  ? 311.761 344.809 434.621 1.00 127.75 ? 14  ARG B CD  1 
ATOM 3461 N NE  . ARG D 4 14  ? 310.920 344.881 435.807 1.00 127.75 ? 14  ARG B NE  1 
ATOM 3462 C CZ  . ARG D 4 14  ? 311.152 345.690 436.830 1.00 127.75 ? 14  ARG B CZ  1 
ATOM 3463 N NH1 . ARG D 4 14  ? 312.195 346.503 436.806 1.00 127.75 ? 14  ARG B NH1 1 
ATOM 3464 N NH2 . ARG D 4 14  ? 310.339 345.692 437.874 1.00 127.75 ? 14  ARG B NH2 1 
ATOM 3465 N N   . SER D 4 15  ? 311.748 339.759 437.156 1.00 125.50 ? 15  SER B N   1 
ATOM 3466 C CA  . SER D 4 15  ? 310.911 338.673 437.679 1.00 125.50 ? 15  SER B CA  1 
ATOM 3467 C C   . SER D 4 15  ? 311.359 337.308 437.149 1.00 125.50 ? 15  SER B C   1 
ATOM 3468 O O   . SER D 4 15  ? 310.638 336.621 436.426 1.00 125.50 ? 15  SER B O   1 
ATOM 3469 C CB  . SER D 4 15  ? 309.424 338.915 437.391 1.00 125.50 ? 15  SER B CB  1 
ATOM 3470 O OG  . SER D 4 15  ? 309.132 338.778 436.012 1.00 125.50 ? 15  SER B OG  1 
ATOM 3471 N N   . ILE D 4 16  ? 312.567 336.934 437.519 1.00 120.04 ? 16  ILE B N   1 
ATOM 3472 C CA  . ILE D 4 16  ? 313.112 335.623 437.190 1.00 120.04 ? 16  ILE B CA  1 
ATOM 3473 C C   . ILE D 4 16  ? 312.678 334.632 438.255 1.00 120.04 ? 16  ILE B C   1 
ATOM 3474 O O   . ILE D 4 16  ? 312.556 334.972 439.435 1.00 120.04 ? 16  ILE B O   1 
ATOM 3475 C CB  . ILE D 4 16  ? 314.646 335.682 437.062 1.00 120.04 ? 16  ILE B CB  1 
ATOM 3476 C CG1 . ILE D 4 16  ? 315.234 336.517 438.198 1.00 120.04 ? 16  ILE B CG1 1 
ATOM 3477 C CG2 . ILE D 4 16  ? 315.040 336.241 435.711 1.00 120.04 ? 16  ILE B CG2 1 
ATOM 3478 C CD1 . ILE D 4 16  ? 316.721 336.741 438.091 1.00 120.04 ? 16  ILE B CD1 1 
ATOM 3479 N N   . THR D 4 17  ? 312.434 333.394 437.841 1.00 119.91 ? 17  THR B N   1 
ATOM 3480 C CA  . THR D 4 17  ? 311.946 332.366 438.744 1.00 119.91 ? 17  THR B CA  1 
ATOM 3481 C C   . THR D 4 17  ? 312.718 331.073 438.538 1.00 119.91 ? 17  THR B C   1 
ATOM 3482 O O   . THR D 4 17  ? 313.147 330.752 437.428 1.00 119.91 ? 17  THR B O   1 
ATOM 3483 C CB  . THR D 4 17  ? 310.446 332.113 438.555 1.00 119.91 ? 17  THR B CB  1 
ATOM 3484 O OG1 . THR D 4 17  ? 310.058 330.956 439.301 1.00 119.91 ? 17  THR B OG1 1 
ATOM 3485 C CG2 . THR D 4 17  ? 310.105 331.911 437.092 1.00 119.91 ? 17  THR B CG2 1 
ATOM 3486 N N   . LEU D 4 18  ? 312.899 330.338 439.631 1.00 114.56 ? 18  LEU B N   1 
ATOM 3487 C CA  . LEU D 4 18  ? 313.608 329.062 439.602 1.00 114.56 ? 18  LEU B CA  1 
ATOM 3488 C C   . LEU D 4 18  ? 312.922 328.144 440.599 1.00 114.56 ? 18  LEU B C   1 
ATOM 3489 O O   . LEU D 4 18  ? 312.883 328.453 441.792 1.00 114.56 ? 18  LEU B O   1 
ATOM 3490 C CB  . LEU D 4 18  ? 315.080 329.238 439.951 1.00 114.56 ? 18  LEU B CB  1 
ATOM 3491 C CG  . LEU D 4 18  ? 316.013 329.779 438.872 1.00 114.56 ? 18  LEU B CG  1 
ATOM 3492 C CD1 . LEU D 4 18  ? 317.422 329.913 439.408 1.00 114.56 ? 18  LEU B CD1 1 
ATOM 3493 C CD2 . LEU D 4 18  ? 315.983 328.875 437.663 1.00 114.56 ? 18  LEU B CD2 1 
ATOM 3494 N N   . GLY D 4 19  ? 312.388 327.028 440.120 1.00 116.67 ? 19  GLY B N   1 
ATOM 3495 C CA  . GLY D 4 19  ? 311.696 326.108 440.996 1.00 116.67 ? 19  GLY B CA  1 
ATOM 3496 C C   . GLY D 4 19  ? 310.376 326.664 441.479 1.00 116.67 ? 19  GLY B C   1 
ATOM 3497 O O   . GLY D 4 19  ? 309.435 326.809 440.696 1.00 116.67 ? 19  GLY B O   1 
ATOM 3498 N N   . ASN D 4 20  ? 310.295 326.987 442.765 1.00 118.96 ? 20  ASN B N   1 
ATOM 3499 C CA  . ASN D 4 20  ? 309.104 327.581 443.354 1.00 118.96 ? 20  ASN B CA  1 
ATOM 3500 C C   . ASN D 4 20  ? 309.464 328.834 444.132 1.00 118.96 ? 20  ASN B C   1 
ATOM 3501 O O   . ASN D 4 20  ? 308.969 329.068 445.235 1.00 118.96 ? 20  ASN B O   1 
ATOM 3502 C CB  . ASN D 4 20  ? 308.377 326.582 444.247 1.00 118.96 ? 20  ASN B CB  1 
ATOM 3503 C CG  . ASN D 4 20  ? 309.278 325.978 445.295 1.00 118.96 ? 20  ASN B CG  1 
ATOM 3504 O OD1 . ASN D 4 20  ? 310.236 325.280 444.977 1.00 118.96 ? 20  ASN B OD1 1 
ATOM 3505 N ND2 . ASN D 4 20  ? 308.973 326.239 446.556 1.00 118.96 ? 20  ASN B ND2 1 
ATOM 3506 N N   . SER D 4 21  ? 310.332 329.664 443.566 1.00 116.97 ? 21  SER B N   1 
ATOM 3507 C CA  . SER D 4 21  ? 310.726 330.914 444.191 1.00 116.97 ? 21  SER B CA  1 
ATOM 3508 C C   . SER D 4 21  ? 310.988 331.943 443.106 1.00 116.97 ? 21  SER B C   1 
ATOM 3509 O O   . SER D 4 21  ? 311.409 331.600 442.000 1.00 116.97 ? 21  SER B O   1 
ATOM 3510 C CB  . SER D 4 21  ? 311.967 330.738 445.057 1.00 116.97 ? 21  SER B CB  1 
ATOM 3511 O OG  . SER D 4 21  ? 313.127 330.739 444.253 1.00 116.97 ? 21  SER B OG  1 
ATOM 3512 N N   . THR D 4 22  ? 310.739 333.210 443.428 1.00 116.64 ? 22  THR B N   1 
ATOM 3513 C CA  . THR D 4 22  ? 310.821 334.287 442.452 1.00 116.64 ? 22  THR B CA  1 
ATOM 3514 C C   . THR D 4 22  ? 311.411 335.528 443.099 1.00 116.64 ? 22  THR B C   1 
ATOM 3515 O O   . THR D 4 22  ? 310.978 335.929 444.182 1.00 116.64 ? 22  THR B O   1 
ATOM 3516 C CB  . THR D 4 22  ? 309.437 334.602 441.881 1.00 116.64 ? 22  THR B CB  1 
ATOM 3517 O OG1 . THR D 4 22  ? 308.858 333.406 441.351 1.00 116.64 ? 22  THR B OG1 1 
ATOM 3518 C CG2 . THR D 4 22  ? 309.528 335.631 440.776 1.00 116.64 ? 22  THR B CG2 1 
ATOM 3519 N N   . ILE D 4 23  ? 312.396 336.134 442.438 1.00 114.55 ? 23  ILE B N   1 
ATOM 3520 C CA  . ILE D 4 23  ? 312.944 337.419 442.841 1.00 114.55 ? 23  ILE B CA  1 
ATOM 3521 C C   . ILE D 4 23  ? 312.696 338.409 441.713 1.00 114.55 ? 23  ILE B C   1 
ATOM 3522 O O   . ILE D 4 23  ? 312.163 338.061 440.663 1.00 114.55 ? 23  ILE B O   1 
ATOM 3523 C CB  . ILE D 4 23  ? 314.443 337.345 443.173 1.00 114.55 ? 23  ILE B CB  1 
ATOM 3524 C CG1 . ILE D 4 23  ? 315.229 336.883 441.955 1.00 114.55 ? 23  ILE B CG1 1 
ATOM 3525 C CG2 . ILE D 4 23  ? 314.679 336.408 444.324 1.00 114.55 ? 23  ILE B CG2 1 
ATOM 3526 C CD1 . ILE D 4 23  ? 316.711 337.057 442.103 1.00 114.55 ? 23  ILE B CD1 1 
ATOM 3527 N N   . THR D 4 24  ? 313.088 339.660 441.945 1.00 122.96 ? 24  THR B N   1 
ATOM 3528 C CA  . THR D 4 24  ? 312.868 340.741 440.992 1.00 122.96 ? 24  THR B CA  1 
ATOM 3529 C C   . THR D 4 24  ? 314.146 341.546 440.813 1.00 122.96 ? 24  THR B C   1 
ATOM 3530 O O   . THR D 4 24  ? 314.742 341.996 441.795 1.00 122.96 ? 24  THR B O   1 
ATOM 3531 C CB  . THR D 4 24  ? 311.742 341.666 441.459 1.00 122.96 ? 24  THR B CB  1 
ATOM 3532 O OG1 . THR D 4 24  ? 311.922 341.971 442.847 1.00 122.96 ? 24  THR B OG1 1 
ATOM 3533 C CG2 . THR D 4 24  ? 310.386 341.016 441.253 1.00 122.96 ? 24  THR B CG2 1 
ATOM 3534 N N   . THR D 4 25  ? 314.566 341.724 439.558 1.00 127.35 ? 25  THR B N   1 
ATOM 3535 C CA  . THR D 4 25  ? 315.735 342.536 439.230 1.00 127.35 ? 25  THR B CA  1 
ATOM 3536 C C   . THR D 4 25  ? 315.358 343.626 438.235 1.00 127.35 ? 25  THR B C   1 
ATOM 3537 O O   . THR D 4 25  ? 314.173 343.847 437.970 1.00 127.35 ? 25  THR B O   1 
ATOM 3538 C CB  . THR D 4 25  ? 316.866 341.691 438.632 1.00 127.35 ? 25  THR B CB  1 
ATOM 3539 O OG1 . THR D 4 25  ? 316.579 341.414 437.256 1.00 127.35 ? 25  THR B OG1 1 
ATOM 3540 C CG2 . THR D 4 25  ? 317.059 340.380 439.379 1.00 127.35 ? 25  THR B CG2 1 
ATOM 3541 N N   . GLN D 4 26  ? 316.354 344.314 437.682 1.00 126.78 ? 26  GLN B N   1 
ATOM 3542 C CA  . GLN D 4 26  ? 316.119 345.245 436.582 1.00 126.78 ? 26  GLN B CA  1 
ATOM 3543 C C   . GLN D 4 26  ? 316.538 344.633 435.251 1.00 126.78 ? 26  GLN B C   1 
ATOM 3544 O O   . GLN D 4 26  ? 317.020 345.332 434.360 1.00 126.78 ? 26  GLN B O   1 
ATOM 3545 C CB  . GLN D 4 26  ? 316.867 346.557 436.798 1.00 126.78 ? 26  GLN B CB  1 
ATOM 3546 C CG  . GLN D 4 26  ? 316.299 347.427 437.894 1.00 126.78 ? 26  GLN B CG  1 
ATOM 3547 C CD  . GLN D 4 26  ? 317.107 347.344 439.165 1.00 126.78 ? 26  GLN B CD  1 
ATOM 3548 O OE1 . GLN D 4 26  ? 317.419 346.254 439.643 1.00 126.78 ? 26  GLN B OE1 1 
ATOM 3549 N NE2 . GLN D 4 26  ? 317.459 348.497 439.720 1.00 126.78 ? 26  GLN B NE2 1 
ATOM 3550 N N   . ASN D 4 30  ? 323.131 344.379 435.226 1.00 117.72 ? 30  ASN B N   1 
ATOM 3551 C CA  . ASN D 4 30  ? 324.552 344.150 434.989 1.00 117.72 ? 30  ASN B CA  1 
ATOM 3552 C C   . ASN D 4 30  ? 325.074 342.995 435.833 1.00 117.72 ? 30  ASN B C   1 
ATOM 3553 O O   . ASN D 4 30  ? 325.027 343.044 437.059 1.00 117.72 ? 30  ASN B O   1 
ATOM 3554 C CB  . ASN D 4 30  ? 325.353 345.413 435.289 1.00 117.72 ? 30  ASN B CB  1 
ATOM 3555 C CG  . ASN D 4 30  ? 326.639 345.482 434.503 1.00 117.72 ? 30  ASN B CG  1 
ATOM 3556 O OD1 . ASN D 4 30  ? 327.091 344.487 433.942 1.00 117.72 ? 30  ASN B OD1 1 
ATOM 3557 N ND2 . ASN D 4 30  ? 327.241 346.662 434.461 1.00 117.72 ? 30  ASN B ND2 1 
ATOM 3558 N N   . VAL D 4 31  ? 325.586 341.962 435.168 1.00 110.91 ? 31  VAL B N   1 
ATOM 3559 C CA  . VAL D 4 31  ? 326.073 340.757 435.826 1.00 110.91 ? 31  VAL B CA  1 
ATOM 3560 C C   . VAL D 4 31  ? 327.515 340.511 435.396 1.00 110.91 ? 31  VAL B C   1 
ATOM 3561 O O   . VAL D 4 31  ? 327.837 340.577 434.204 1.00 110.91 ? 31  VAL B O   1 
ATOM 3562 C CB  . VAL D 4 31  ? 325.164 339.546 435.521 1.00 110.91 ? 31  VAL B CB  1 
ATOM 3563 C CG1 . VAL D 4 31  ? 324.829 339.453 434.039 1.00 110.91 ? 31  VAL B CG1 1 
ATOM 3564 C CG2 . VAL D 4 31  ? 325.791 338.253 435.996 1.00 110.91 ? 31  VAL B CG2 1 
ATOM 3565 N N   . VAL D 4 32  ? 328.390 340.279 436.368 1.00 103.24 ? 32  VAL B N   1 
ATOM 3566 C CA  . VAL D 4 32  ? 329.780 339.924 436.110 1.00 103.24 ? 32  VAL B CA  1 
ATOM 3567 C C   . VAL D 4 32  ? 329.956 338.432 436.362 1.00 103.24 ? 32  VAL B C   1 
ATOM 3568 O O   . VAL D 4 32  ? 329.664 337.928 437.452 1.00 103.24 ? 32  VAL B O   1 
ATOM 3569 C CB  . VAL D 4 32  ? 330.747 340.787 436.940 1.00 103.24 ? 32  VAL B CB  1 
ATOM 3570 C CG1 . VAL D 4 32  ? 330.315 340.902 438.391 1.00 103.24 ? 32  VAL B CG1 1 
ATOM 3571 C CG2 . VAL D 4 32  ? 332.143 340.211 436.874 1.00 103.24 ? 32  VAL B CG2 1 
ATOM 3572 N N   . VAL D 4 33  ? 330.397 337.711 435.341 1.00 101.54 ? 33  VAL B N   1 
ATOM 3573 C CA  . VAL D 4 33  ? 330.438 336.258 435.373 1.00 101.54 ? 33  VAL B CA  1 
ATOM 3574 C C   . VAL D 4 33  ? 331.883 335.801 435.535 1.00 101.54 ? 33  VAL B C   1 
ATOM 3575 O O   . VAL D 4 33  ? 332.738 336.080 434.686 1.00 101.54 ? 33  VAL B O   1 
ATOM 3576 C CB  . VAL D 4 33  ? 329.752 335.643 434.141 1.00 101.54 ? 33  VAL B CB  1 
ATOM 3577 C CG1 . VAL D 4 33  ? 330.174 336.315 432.840 1.00 101.54 ? 33  VAL B CG1 1 
ATOM 3578 C CG2 . VAL D 4 33  ? 330.047 334.171 434.072 1.00 101.54 ? 33  VAL B CG2 1 
ATOM 3579 N N   . GLY D 4 34  ? 332.151 335.162 436.678 1.00 101.57 ? 34  GLY B N   1 
ATOM 3580 C CA  . GLY D 4 34  ? 333.331 334.370 436.995 1.00 101.57 ? 34  GLY B CA  1 
ATOM 3581 C C   . GLY D 4 34  ? 334.693 334.818 436.515 1.00 101.57 ? 34  GLY B C   1 
ATOM 3582 O O   . GLY D 4 34  ? 335.041 335.998 436.596 1.00 101.57 ? 34  GLY B O   1 
ATOM 3583 N N   . TYR D 4 35  ? 335.463 333.871 435.994 1.00 95.40  ? 35  TYR B N   1 
ATOM 3584 C CA  . TYR D 4 35  ? 336.717 334.151 435.314 1.00 95.40  ? 35  TYR B CA  1 
ATOM 3585 C C   . TYR D 4 35  ? 336.530 334.044 433.808 1.00 95.40  ? 35  TYR B C   1 
ATOM 3586 O O   . TYR D 4 35  ? 337.442 333.677 433.069 1.00 95.40  ? 35  TYR B O   1 
ATOM 3587 C CB  . TYR D 4 35  ? 337.814 333.215 435.801 1.00 95.40  ? 35  TYR B CB  1 
ATOM 3588 C CG  . TYR D 4 35  ? 338.335 333.606 437.152 1.00 95.40  ? 35  TYR B CG  1 
ATOM 3589 C CD1 . TYR D 4 35  ? 337.731 333.142 438.308 1.00 95.40  ? 35  TYR B CD1 1 
ATOM 3590 C CD2 . TYR D 4 35  ? 339.416 334.460 437.273 1.00 95.40  ? 35  TYR B CD2 1 
ATOM 3591 C CE1 . TYR D 4 35  ? 338.200 333.510 439.546 1.00 95.40  ? 35  TYR B CE1 1 
ATOM 3592 C CE2 . TYR D 4 35  ? 339.891 334.833 438.505 1.00 95.40  ? 35  TYR B CE2 1 
ATOM 3593 C CZ  . TYR D 4 35  ? 339.280 334.354 439.636 1.00 95.40  ? 35  TYR B CZ  1 
ATOM 3594 O OH  . TYR D 4 35  ? 339.752 334.732 440.866 1.00 95.40  ? 35  TYR B OH  1 
ATOM 3595 N N   . GLY D 4 36  ? 335.328 334.370 433.348 1.00 102.57 ? 36  GLY B N   1 
ATOM 3596 C CA  . GLY D 4 36  ? 335.024 334.340 431.937 1.00 102.57 ? 36  GLY B CA  1 
ATOM 3597 C C   . GLY D 4 36  ? 334.246 333.135 431.477 1.00 102.57 ? 36  GLY B C   1 
ATOM 3598 O O   . GLY D 4 36  ? 333.836 333.089 430.315 1.00 102.57 ? 36  GLY B O   1 
ATOM 3599 N N   . VAL D 4 37  ? 334.013 332.158 432.351 1.00 110.17 ? 37  VAL B N   1 
ATOM 3600 C CA  . VAL D 4 37  ? 333.331 330.927 431.975 1.00 110.17 ? 37  VAL B CA  1 
ATOM 3601 C C   . VAL D 4 37  ? 331.986 330.852 432.685 1.00 110.17 ? 37  VAL B C   1 
ATOM 3602 O O   . VAL D 4 37  ? 331.814 331.385 433.786 1.00 110.17 ? 37  VAL B O   1 
ATOM 3603 C CB  . VAL D 4 37  ? 334.193 329.675 432.264 1.00 110.17 ? 37  VAL B CB  1 
ATOM 3604 C CG1 . VAL D 4 37  ? 335.559 329.820 431.625 1.00 110.17 ? 37  VAL B CG1 1 
ATOM 3605 C CG2 . VAL D 4 37  ? 334.352 329.427 433.750 1.00 110.17 ? 37  VAL B CG2 1 
ATOM 3606 N N   . TRP D 4 38  ? 331.021 330.242 432.021 1.00 114.76 ? 38  TRP B N   1 
ATOM 3607 C CA  . TRP D 4 38  ? 329.713 329.965 432.579 1.00 114.76 ? 38  TRP B CA  1 
ATOM 3608 C C   . TRP D 4 38  ? 329.723 328.585 433.229 1.00 114.76 ? 38  TRP B C   1 
ATOM 3609 O O   . TRP D 4 38  ? 330.405 327.678 432.748 1.00 114.76 ? 38  TRP B O   1 
ATOM 3610 C CB  . TRP D 4 38  ? 328.654 330.021 431.482 1.00 114.76 ? 38  TRP B CB  1 
ATOM 3611 C CG  . TRP D 4 38  ? 327.266 330.288 431.967 1.00 114.76 ? 38  TRP B CG  1 
ATOM 3612 C CD1 . TRP D 4 38  ? 326.285 329.368 432.181 1.00 114.76 ? 38  TRP B CD1 1 
ATOM 3613 C CD2 . TRP D 4 38  ? 326.700 331.561 432.294 1.00 114.76 ? 38  TRP B CD2 1 
ATOM 3614 N NE1 . TRP D 4 38  ? 325.145 329.986 432.625 1.00 114.76 ? 38  TRP B NE1 1 
ATOM 3615 C CE2 . TRP D 4 38  ? 325.374 331.334 432.703 1.00 114.76 ? 38  TRP B CE2 1 
ATOM 3616 C CE3 . TRP D 4 38  ? 327.185 332.869 432.281 1.00 114.76 ? 38  TRP B CE3 1 
ATOM 3617 C CZ2 . TRP D 4 38  ? 324.530 332.364 433.096 1.00 114.76 ? 38  TRP B CZ2 1 
ATOM 3618 C CZ3 . TRP D 4 38  ? 326.346 333.889 432.674 1.00 114.76 ? 38  TRP B CZ3 1 
ATOM 3619 C CH2 . TRP D 4 38  ? 325.033 333.632 433.074 1.00 114.76 ? 38  TRP B CH2 1 
ATOM 3620 N N   . PRO D 4 39  ? 329.003 328.405 434.335 1.00 119.12 ? 39  PRO B N   1 
ATOM 3621 C CA  . PRO D 4 39  ? 329.005 327.099 435.002 1.00 119.12 ? 39  PRO B CA  1 
ATOM 3622 C C   . PRO D 4 39  ? 328.261 326.052 434.193 1.00 119.12 ? 39  PRO B C   1 
ATOM 3623 O O   . PRO D 4 39  ? 327.135 326.271 433.744 1.00 119.12 ? 39  PRO B O   1 
ATOM 3624 C CB  . PRO D 4 39  ? 328.296 327.379 436.331 1.00 119.12 ? 39  PRO B CB  1 
ATOM 3625 C CG  . PRO D 4 39  ? 328.426 328.838 436.526 1.00 119.12 ? 39  PRO B CG  1 
ATOM 3626 C CD  . PRO D 4 39  ? 328.352 329.428 435.163 1.00 119.12 ? 39  PRO B CD  1 
ATOM 3627 N N   . GLU D 4 40  ? 328.906 324.903 434.015 1.00 133.03 ? 40  GLU B N   1 
ATOM 3628 C CA  . GLU D 4 40  ? 328.354 323.816 433.220 1.00 133.03 ? 40  GLU B CA  1 
ATOM 3629 C C   . GLU D 4 40  ? 328.718 322.497 433.880 1.00 133.03 ? 40  GLU B C   1 
ATOM 3630 O O   . GLU D 4 40  ? 329.463 322.466 434.862 1.00 133.03 ? 40  GLU B O   1 
ATOM 3631 C CB  . GLU D 4 40  ? 328.876 323.846 431.780 1.00 133.03 ? 40  GLU B CB  1 
ATOM 3632 C CG  . GLU D 4 40  ? 328.183 324.853 430.878 1.00 133.03 ? 40  GLU B CG  1 
ATOM 3633 C CD  . GLU D 4 40  ? 326.923 324.303 430.235 1.00 133.03 ? 40  GLU B CD  1 
ATOM 3634 O OE1 . GLU D 4 40  ? 326.257 325.055 429.492 1.00 133.03 ? 40  GLU B OE1 1 
ATOM 3635 O OE2 . GLU D 4 40  ? 326.602 323.118 430.462 1.00 133.03 ? 40  GLU B OE2 1 
ATOM 3636 N N   . TYR D 4 41  ? 328.193 321.409 433.324 1.00 134.09 ? 41  TYR B N   1 
ATOM 3637 C CA  . TYR D 4 41  ? 328.437 320.087 433.877 1.00 134.09 ? 41  TYR B CA  1 
ATOM 3638 C C   . TYR D 4 41  ? 329.816 319.578 433.459 1.00 134.09 ? 41  TYR B C   1 
ATOM 3639 O O   . TYR D 4 41  ? 330.644 320.306 432.904 1.00 134.09 ? 41  TYR B O   1 
ATOM 3640 C CB  . TYR D 4 41  ? 327.349 319.116 433.430 1.00 134.09 ? 41  TYR B CB  1 
ATOM 3641 C CG  . TYR D 4 41  ? 325.999 319.371 434.049 1.00 134.09 ? 41  TYR B CG  1 
ATOM 3642 C CD1 . TYR D 4 41  ? 325.801 319.217 435.412 1.00 134.09 ? 41  TYR B CD1 1 
ATOM 3643 C CD2 . TYR D 4 41  ? 324.919 319.753 433.268 1.00 134.09 ? 41  TYR B CD2 1 
ATOM 3644 C CE1 . TYR D 4 41  ? 324.563 319.448 435.985 1.00 134.09 ? 41  TYR B CE1 1 
ATOM 3645 C CE2 . TYR D 4 41  ? 323.680 319.983 433.829 1.00 134.09 ? 41  TYR B CE2 1 
ATOM 3646 C CZ  . TYR D 4 41  ? 323.508 319.827 435.186 1.00 134.09 ? 41  TYR B CZ  1 
ATOM 3647 O OH  . TYR D 4 41  ? 322.275 320.055 435.748 1.00 134.09 ? 41  TYR B OH  1 
ATOM 3648 N N   . LEU D 4 42  ? 330.065 318.303 433.736 1.00 127.95 ? 42  LEU B N   1 
ATOM 3649 C CA  . LEU D 4 42  ? 331.337 317.683 433.387 1.00 127.95 ? 42  LEU B CA  1 
ATOM 3650 C C   . LEU D 4 42  ? 331.433 317.411 431.890 1.00 127.95 ? 42  LEU B C   1 
ATOM 3651 O O   . LEU D 4 42  ? 331.393 316.263 431.454 1.00 127.95 ? 42  LEU B O   1 
ATOM 3652 C CB  . LEU D 4 42  ? 331.527 316.388 434.170 1.00 127.95 ? 42  LEU B CB  1 
ATOM 3653 C CG  . LEU D 4 42  ? 332.378 316.524 435.430 1.00 127.95 ? 42  LEU B CG  1 
ATOM 3654 C CD1 . LEU D 4 42  ? 332.274 315.279 436.288 1.00 127.95 ? 42  LEU B CD1 1 
ATOM 3655 C CD2 . LEU D 4 42  ? 333.819 316.796 435.053 1.00 127.95 ? 42  LEU B CD2 1 
ATOM 3656 N N   . ASP D 4 51  ? 332.986 305.436 439.589 1.00 157.90 ? 51  ASP B N   1 
ATOM 3657 C CA  . ASP D 4 51  ? 331.541 305.328 439.444 1.00 157.90 ? 51  ASP B CA  1 
ATOM 3658 C C   . ASP D 4 51  ? 330.973 306.515 438.681 1.00 157.90 ? 51  ASP B C   1 
ATOM 3659 O O   . ASP D 4 51  ? 331.706 307.429 438.307 1.00 157.90 ? 51  ASP B O   1 
ATOM 3660 C CB  . ASP D 4 51  ? 330.871 305.191 440.817 1.00 157.90 ? 51  ASP B CB  1 
ATOM 3661 C CG  . ASP D 4 51  ? 331.391 306.195 441.836 1.00 157.90 ? 51  ASP B CG  1 
ATOM 3662 O OD1 . ASP D 4 51  ? 332.275 307.009 441.496 1.00 157.90 ? 51  ASP B OD1 1 
ATOM 3663 O OD2 . ASP D 4 51  ? 330.926 306.147 442.993 1.00 157.90 ? 51  ASP B OD2 1 
ATOM 3664 N N   . GLN D 4 52  ? 329.669 306.494 438.449 1.00 158.38 ? 52  GLN B N   1 
ATOM 3665 C CA  . GLN D 4 52  ? 329.083 307.517 437.596 1.00 158.38 ? 52  GLN B CA  1 
ATOM 3666 C C   . GLN D 4 52  ? 328.301 308.519 438.428 1.00 158.38 ? 52  GLN B C   1 
ATOM 3667 O O   . GLN D 4 52  ? 327.691 308.134 439.436 1.00 158.38 ? 52  GLN B O   1 
ATOM 3668 C CB  . GLN D 4 52  ? 328.167 306.879 436.551 1.00 158.38 ? 52  GLN B CB  1 
ATOM 3669 C CG  . GLN D 4 52  ? 328.866 306.148 435.380 1.00 158.38 ? 52  GLN B CG  1 
ATOM 3670 C CD  . GLN D 4 52  ? 329.781 307.004 434.488 1.00 158.38 ? 52  GLN B CD  1 
ATOM 3671 O OE1 . GLN D 4 52  ? 329.822 308.233 434.573 1.00 158.38 ? 52  GLN B OE1 1 
ATOM 3672 N NE2 . GLN D 4 52  ? 330.531 306.329 433.625 1.00 158.38 ? 52  GLN B NE2 1 
ATOM 3673 N N   . PRO D 4 53  ? 328.296 309.797 438.051 1.00 154.10 ? 53  PRO B N   1 
ATOM 3674 C CA  . PRO D 4 53  ? 327.577 310.800 438.842 1.00 154.10 ? 53  PRO B CA  1 
ATOM 3675 C C   . PRO D 4 53  ? 326.098 310.869 438.500 1.00 154.10 ? 53  PRO B C   1 
ATOM 3676 O O   . PRO D 4 53  ? 325.678 310.555 437.384 1.00 154.10 ? 53  PRO B O   1 
ATOM 3677 C CB  . PRO D 4 53  ? 328.284 312.105 438.462 1.00 154.10 ? 53  PRO B CB  1 
ATOM 3678 C CG  . PRO D 4 53  ? 328.741 311.876 437.077 1.00 154.10 ? 53  PRO B CG  1 
ATOM 3679 C CD  . PRO D 4 53  ? 329.114 310.420 436.995 1.00 154.10 ? 53  PRO B CD  1 
ATOM 3680 N N   . THR D 4 54  ? 325.306 311.288 439.480 1.00 146.64 ? 54  THR B N   1 
ATOM 3681 C CA  . THR D 4 54  ? 323.903 311.612 439.280 1.00 146.64 ? 54  THR B CA  1 
ATOM 3682 C C   . THR D 4 54  ? 323.720 313.124 439.269 1.00 146.64 ? 54  THR B C   1 
ATOM 3683 O O   . THR D 4 54  ? 324.467 313.868 439.906 1.00 146.64 ? 54  THR B O   1 
ATOM 3684 C CB  . THR D 4 54  ? 323.030 310.986 440.370 1.00 146.64 ? 54  THR B CB  1 
ATOM 3685 O OG1 . THR D 4 54  ? 323.090 311.787 441.554 1.00 146.64 ? 54  THR B OG1 1 
ATOM 3686 C CG2 . THR D 4 54  ? 323.510 309.590 440.692 1.00 146.64 ? 54  THR B CG2 1 
ATOM 3687 N N   . GLN D 4 55  ? 322.709 313.576 438.529 1.00 142.77 ? 55  GLN B N   1 
ATOM 3688 C CA  . GLN D 4 55  ? 322.493 314.995 438.259 1.00 142.77 ? 55  GLN B CA  1 
ATOM 3689 C C   . GLN D 4 55  ? 321.098 315.402 438.717 1.00 142.77 ? 55  GLN B C   1 
ATOM 3690 O O   . GLN D 4 55  ? 320.129 315.282 437.954 1.00 142.77 ? 55  GLN B O   1 
ATOM 3691 C CB  . GLN D 4 55  ? 322.679 315.287 436.774 1.00 142.77 ? 55  GLN B CB  1 
ATOM 3692 C CG  . GLN D 4 55  ? 324.093 315.067 436.280 1.00 142.77 ? 55  GLN B CG  1 
ATOM 3693 C CD  . GLN D 4 55  ? 324.303 315.580 434.870 1.00 142.77 ? 55  GLN B CD  1 
ATOM 3694 O OE1 . GLN D 4 55  ? 323.932 316.706 434.546 1.00 142.77 ? 55  GLN B OE1 1 
ATOM 3695 N NE2 . GLN D 4 55  ? 324.901 314.753 434.021 1.00 142.77 ? 55  GLN B NE2 1 
ATOM 3696 N N   . PRO D 4 56  ? 320.951 315.883 439.956 1.00 143.65 ? 56  PRO B N   1 
ATOM 3697 C CA  . PRO D 4 56  ? 319.656 316.439 440.373 1.00 143.65 ? 56  PRO B CA  1 
ATOM 3698 C C   . PRO D 4 56  ? 319.568 317.939 440.144 1.00 143.65 ? 56  PRO B C   1 
ATOM 3699 O O   . PRO D 4 56  ? 320.522 318.678 440.404 1.00 143.65 ? 56  PRO B O   1 
ATOM 3700 C CB  . PRO D 4 56  ? 319.591 316.090 441.863 1.00 143.65 ? 56  PRO B CB  1 
ATOM 3701 C CG  . PRO D 4 56  ? 321.010 316.068 442.292 1.00 143.65 ? 56  PRO B CG  1 
ATOM 3702 C CD  . PRO D 4 56  ? 321.867 315.712 441.095 1.00 143.65 ? 56  PRO B CD  1 
ATOM 3703 N N   . ASP D 4 57  ? 318.423 318.399 439.645 1.00 145.63 ? 57  ASP B N   1 
ATOM 3704 C CA  . ASP D 4 57  ? 318.254 319.801 439.290 1.00 145.63 ? 57  ASP B CA  1 
ATOM 3705 C C   . ASP D 4 57  ? 316.958 320.422 439.770 1.00 145.63 ? 57  ASP B C   1 
ATOM 3706 O O   . ASP D 4 57  ? 316.907 321.650 439.903 1.00 145.63 ? 57  ASP B O   1 
ATOM 3707 C CB  . ASP D 4 57  ? 318.334 319.972 437.770 1.00 145.63 ? 57  ASP B CB  1 
ATOM 3708 C CG  . ASP D 4 57  ? 317.457 318.988 437.038 1.00 145.63 ? 57  ASP B CG  1 
ATOM 3709 O OD1 . ASP D 4 57  ? 316.975 318.035 437.684 1.00 145.63 ? 57  ASP B OD1 1 
ATOM 3710 O OD2 . ASP D 4 57  ? 317.249 319.163 435.821 1.00 145.63 ? 57  ASP B OD2 1 
ATOM 3711 N N   . VAL D 4 58  ? 315.912 319.637 440.029 1.00 147.69 ? 58  VAL B N   1 
ATOM 3712 C CA  . VAL D 4 58  ? 314.631 320.223 440.395 1.00 147.69 ? 58  VAL B CA  1 
ATOM 3713 C C   . VAL D 4 58  ? 314.649 320.749 441.821 1.00 147.69 ? 58  VAL B C   1 
ATOM 3714 O O   . VAL D 4 58  ? 314.253 321.895 442.066 1.00 147.69 ? 58  VAL B O   1 
ATOM 3715 C CB  . VAL D 4 58  ? 313.502 319.190 440.201 1.00 147.69 ? 58  VAL B CB  1 
ATOM 3716 C CG1 . VAL D 4 58  ? 312.200 319.670 440.834 1.00 147.69 ? 58  VAL B CG1 1 
ATOM 3717 C CG2 . VAL D 4 58  ? 313.301 318.901 438.722 1.00 147.69 ? 58  VAL B CG2 1 
ATOM 3718 N N   . ALA D 4 59  ? 315.151 319.965 442.763 1.00 139.74 ? 59  ALA B N   1 
ATOM 3719 C CA  . ALA D 4 59  ? 315.043 320.302 444.169 1.00 139.74 ? 59  ALA B CA  1 
ATOM 3720 C C   . ALA D 4 59  ? 316.222 321.111 444.689 1.00 139.74 ? 59  ALA B C   1 
ATOM 3721 O O   . ALA D 4 59  ? 316.257 321.431 445.879 1.00 139.74 ? 59  ALA B O   1 
ATOM 3722 C CB  . ALA D 4 59  ? 314.878 319.027 444.991 1.00 139.74 ? 59  ALA B CB  1 
ATOM 3723 N N   . THR D 4 60  ? 317.189 321.445 443.841 1.00 131.01 ? 60  THR B N   1 
ATOM 3724 C CA  . THR D 4 60  ? 318.327 322.245 444.271 1.00 131.01 ? 60  THR B CA  1 
ATOM 3725 C C   . THR D 4 60  ? 318.333 323.628 443.647 1.00 131.01 ? 60  THR B C   1 
ATOM 3726 O O   . THR D 4 60  ? 318.740 324.592 444.301 1.00 131.01 ? 60  THR B O   1 
ATOM 3727 C CB  . THR D 4 60  ? 319.646 321.534 443.943 1.00 131.01 ? 60  THR B CB  1 
ATOM 3728 O OG1 . THR D 4 60  ? 319.904 321.638 442.539 1.00 131.01 ? 60  THR B OG1 1 
ATOM 3729 C CG2 . THR D 4 60  ? 319.588 320.072 444.340 1.00 131.01 ? 60  THR B CG2 1 
ATOM 3730 N N   . CYS D 4 61  ? 317.898 323.758 442.395 1.00 120.70 ? 61  CYS B N   1 
ATOM 3731 C CA  . CYS D 4 61  ? 317.959 325.033 441.684 1.00 120.70 ? 61  CYS B CA  1 
ATOM 3732 C C   . CYS D 4 61  ? 316.812 325.927 442.143 1.00 120.70 ? 61  CYS B C   1 
ATOM 3733 O O   . CYS D 4 61  ? 315.741 325.984 441.538 1.00 120.70 ? 61  CYS B O   1 
ATOM 3734 C CB  . CYS D 4 61  ? 317.912 324.806 440.181 1.00 120.70 ? 61  CYS B CB  1 
ATOM 3735 S SG  . CYS D 4 61  ? 318.604 326.148 439.209 1.00 120.70 ? 61  CYS B SG  1 
ATOM 3736 N N   . ARG D 4 62  ? 317.047 326.642 443.240 1.00 110.15 ? 62  ARG B N   1 
ATOM 3737 C CA  . ARG D 4 62  ? 316.094 327.623 443.734 1.00 110.15 ? 62  ARG B CA  1 
ATOM 3738 C C   . ARG D 4 62  ? 316.855 328.670 444.527 1.00 110.15 ? 62  ARG B C   1 
ATOM 3739 O O   . ARG D 4 62  ? 318.042 328.508 444.804 1.00 110.15 ? 62  ARG B O   1 
ATOM 3740 C CB  . ARG D 4 62  ? 315.005 326.976 444.591 1.00 110.15 ? 62  ARG B CB  1 
ATOM 3741 C CG  . ARG D 4 62  ? 315.483 326.448 445.916 1.00 110.15 ? 62  ARG B CG  1 
ATOM 3742 C CD  . ARG D 4 62  ? 314.346 325.794 446.675 1.00 110.15 ? 62  ARG B CD  1 
ATOM 3743 N NE  . ARG D 4 62  ? 313.282 326.740 446.981 1.00 110.15 ? 62  ARG B NE  1 
ATOM 3744 C CZ  . ARG D 4 62  ? 313.212 327.436 448.107 1.00 110.15 ? 62  ARG B CZ  1 
ATOM 3745 N NH1 . ARG D 4 62  ? 314.146 327.290 449.029 1.00 110.15 ? 62  ARG B NH1 1 
ATOM 3746 N NH2 . ARG D 4 62  ? 312.214 328.278 448.312 1.00 110.15 ? 62  ARG B NH2 1 
ATOM 3747 N N   . PHE D 4 63  ? 316.163 329.745 444.884 1.00 109.69 ? 63  PHE B N   1 
ATOM 3748 C CA  . PHE D 4 63  ? 316.800 330.892 445.527 1.00 109.69 ? 63  PHE B CA  1 
ATOM 3749 C C   . PHE D 4 63  ? 316.732 330.738 447.040 1.00 109.69 ? 63  PHE B C   1 
ATOM 3750 O O   . PHE D 4 63  ? 315.677 330.920 447.646 1.00 109.69 ? 63  PHE B O   1 
ATOM 3751 C CB  . PHE D 4 63  ? 316.130 332.186 445.087 1.00 109.69 ? 63  PHE B CB  1 
ATOM 3752 C CG  . PHE D 4 63  ? 316.391 332.549 443.661 1.00 109.69 ? 63  PHE B CG  1 
ATOM 3753 C CD1 . PHE D 4 63  ? 317.546 333.215 443.303 1.00 109.69 ? 63  PHE B CD1 1 
ATOM 3754 C CD2 . PHE D 4 63  ? 315.476 332.233 442.677 1.00 109.69 ? 63  PHE B CD2 1 
ATOM 3755 C CE1 . PHE D 4 63  ? 317.785 333.554 441.994 1.00 109.69 ? 63  PHE B CE1 1 
ATOM 3756 C CE2 . PHE D 4 63  ? 315.710 332.568 441.365 1.00 109.69 ? 63  PHE B CE2 1 
ATOM 3757 C CZ  . PHE D 4 63  ? 316.866 333.229 441.024 1.00 109.69 ? 63  PHE B CZ  1 
ATOM 3758 N N   . TYR D 4 64  ? 317.859 330.416 447.661 1.00 106.17 ? 64  TYR B N   1 
ATOM 3759 C CA  . TYR D 4 64  ? 317.935 330.372 449.114 1.00 106.17 ? 64  TYR B CA  1 
ATOM 3760 C C   . TYR D 4 64  ? 318.352 331.738 449.637 1.00 106.17 ? 64  TYR B C   1 
ATOM 3761 O O   . TYR D 4 64  ? 319.527 332.102 449.561 1.00 106.17 ? 64  TYR B O   1 
ATOM 3762 C CB  . TYR D 4 64  ? 318.921 329.303 449.566 1.00 106.17 ? 64  TYR B CB  1 
ATOM 3763 C CG  . TYR D 4 64  ? 318.538 327.906 449.154 1.00 106.17 ? 64  TYR B CG  1 
ATOM 3764 C CD1 . TYR D 4 64  ? 317.528 327.225 449.811 1.00 106.17 ? 64  TYR B CD1 1 
ATOM 3765 C CD2 . TYR D 4 64  ? 319.190 327.267 448.112 1.00 106.17 ? 64  TYR B CD2 1 
ATOM 3766 C CE1 . TYR D 4 64  ? 317.175 325.952 449.441 1.00 106.17 ? 64  TYR B CE1 1 
ATOM 3767 C CE2 . TYR D 4 64  ? 318.844 325.993 447.735 1.00 106.17 ? 64  TYR B CE2 1 
ATOM 3768 C CZ  . TYR D 4 64  ? 317.835 325.343 448.404 1.00 106.17 ? 64  TYR B CZ  1 
ATOM 3769 O OH  . TYR D 4 64  ? 317.481 324.072 448.035 1.00 106.17 ? 64  TYR B OH  1 
ATOM 3770 N N   . THR D 4 65  ? 317.398 332.488 450.177 1.00 101.48 ? 65  THR B N   1 
ATOM 3771 C CA  . THR D 4 65  ? 317.626 333.852 450.637 1.00 101.48 ? 65  THR B CA  1 
ATOM 3772 C C   . THR D 4 65  ? 318.010 333.825 452.106 1.00 101.48 ? 65  THR B C   1 
ATOM 3773 O O   . THR D 4 65  ? 317.203 333.431 452.953 1.00 101.48 ? 65  THR B O   1 
ATOM 3774 C CB  . THR D 4 65  ? 316.382 334.714 450.433 1.00 101.48 ? 65  THR B CB  1 
ATOM 3775 O OG1 . THR D 4 65  ? 316.142 334.885 449.033 1.00 101.48 ? 65  THR B OG1 1 
ATOM 3776 C CG2 . THR D 4 65  ? 316.569 336.070 451.069 1.00 101.48 ? 65  THR B CG2 1 
ATOM 3777 N N   . LEU D 4 66  ? 319.233 334.239 452.406 1.00 101.31 ? 66  LEU B N   1 
ATOM 3778 C CA  . LEU D 4 66  ? 319.660 334.331 453.789 1.00 101.31 ? 66  LEU B CA  1 
ATOM 3779 C C   . LEU D 4 66  ? 319.014 335.536 454.457 1.00 101.31 ? 66  LEU B C   1 
ATOM 3780 O O   . LEU D 4 66  ? 318.474 336.426 453.798 1.00 101.31 ? 66  LEU B O   1 
ATOM 3781 C CB  . LEU D 4 66  ? 321.180 334.433 453.880 1.00 101.31 ? 66  LEU B CB  1 
ATOM 3782 C CG  . LEU D 4 66  ? 321.963 333.398 453.081 1.00 101.31 ? 66  LEU B CG  1 
ATOM 3783 C CD1 . LEU D 4 66  ? 323.438 333.633 453.250 1.00 101.31 ? 66  LEU B CD1 1 
ATOM 3784 C CD2 . LEU D 4 66  ? 321.601 332.005 453.529 1.00 101.31 ? 66  LEU B CD2 1 
ATOM 3785 N N   . GLU D 4 67  ? 319.071 335.558 455.784 1.00 106.22 ? 67  GLU B N   1 
ATOM 3786 C CA  . GLU D 4 67  ? 318.443 336.646 456.514 1.00 106.22 ? 67  GLU B CA  1 
ATOM 3787 C C   . GLU D 4 67  ? 319.300 337.905 456.422 1.00 106.22 ? 67  GLU B C   1 
ATOM 3788 O O   . GLU D 4 67  ? 320.501 337.855 456.151 1.00 106.22 ? 67  GLU B O   1 
ATOM 3789 C CB  . GLU D 4 67  ? 318.202 336.250 457.969 1.00 106.22 ? 67  GLU B CB  1 
ATOM 3790 C CG  . GLU D 4 67  ? 317.049 335.251 458.156 1.00 106.22 ? 67  GLU B CG  1 
ATOM 3791 C CD  . GLU D 4 67  ? 315.795 335.598 457.354 1.00 106.22 ? 67  GLU B CD  1 
ATOM 3792 O OE1 . GLU D 4 67  ? 315.243 336.699 457.551 1.00 106.22 ? 67  GLU B OE1 1 
ATOM 3793 O OE2 . GLU D 4 67  ? 315.352 334.765 456.534 1.00 106.22 ? 67  GLU B OE2 1 
ATOM 3794 N N   . SER D 4 68  ? 318.661 339.046 456.644 1.00 103.19 ? 68  SER B N   1 
ATOM 3795 C CA  . SER D 4 68  ? 319.246 340.329 456.291 1.00 103.19 ? 68  SER B CA  1 
ATOM 3796 C C   . SER D 4 68  ? 320.065 340.912 457.432 1.00 103.19 ? 68  SER B C   1 
ATOM 3797 O O   . SER D 4 68  ? 319.627 340.931 458.584 1.00 103.19 ? 68  SER B O   1 
ATOM 3798 C CB  . SER D 4 68  ? 318.153 341.314 455.887 1.00 103.19 ? 68  SER B CB  1 
ATOM 3799 O OG  . SER D 4 68  ? 317.777 341.112 454.537 1.00 103.19 ? 68  SER B OG  1 
ATOM 3800 N N   . VAL D 4 69  ? 321.250 341.403 457.094 1.00 100.85 ? 69  VAL B N   1 
ATOM 3801 C CA  . VAL D 4 69  ? 322.130 342.055 458.042 1.00 100.85 ? 69  VAL B CA  1 
ATOM 3802 C C   . VAL D 4 69  ? 321.873 343.553 457.990 1.00 100.85 ? 69  VAL B C   1 
ATOM 3803 O O   . VAL D 4 69  ? 321.299 344.080 457.037 1.00 100.85 ? 69  VAL B O   1 
ATOM 3804 C CB  . VAL D 4 69  ? 323.606 341.735 457.747 1.00 100.85 ? 69  VAL B CB  1 
ATOM 3805 C CG1 . VAL D 4 69  ? 323.839 340.250 457.852 1.00 100.85 ? 69  VAL B CG1 1 
ATOM 3806 C CG2 . VAL D 4 69  ? 323.979 342.223 456.369 1.00 100.85 ? 69  VAL B CG2 1 
ATOM 3807 N N   . GLN D 4 70  ? 322.296 344.256 459.034 1.00 105.32 ? 70  GLN B N   1 
ATOM 3808 C CA  . GLN D 4 70  ? 322.080 345.690 459.146 1.00 105.32 ? 70  GLN B CA  1 
ATOM 3809 C C   . GLN D 4 70  ? 323.400 346.424 458.988 1.00 105.32 ? 70  GLN B C   1 
ATOM 3810 O O   . GLN D 4 70  ? 324.377 346.099 459.667 1.00 105.32 ? 70  GLN B O   1 
ATOM 3811 C CB  . GLN D 4 70  ? 321.445 346.048 460.486 1.00 105.32 ? 70  GLN B CB  1 
ATOM 3812 C CG  . GLN D 4 70  ? 319.941 345.976 460.490 1.00 105.32 ? 70  GLN B CG  1 
ATOM 3813 C CD  . GLN D 4 70  ? 319.370 346.090 461.881 1.00 105.32 ? 70  GLN B CD  1 
ATOM 3814 O OE1 . GLN D 4 70  ? 320.106 346.137 462.865 1.00 105.32 ? 70  GLN B OE1 1 
ATOM 3815 N NE2 . GLN D 4 70  ? 318.048 346.134 461.975 1.00 105.32 ? 70  GLN B NE2 1 
ATOM 3816 N N   . TRP D 4 71  ? 323.419 347.413 458.103 1.00 101.82 ? 71  TRP B N   1 
ATOM 3817 C CA  . TRP D 4 71  ? 324.593 348.244 457.860 1.00 101.82 ? 71  TRP B CA  1 
ATOM 3818 C C   . TRP D 4 71  ? 324.378 349.548 458.614 1.00 101.82 ? 71  TRP B C   1 
ATOM 3819 O O   . TRP D 4 71  ? 323.548 350.370 458.228 1.00 101.82 ? 71  TRP B O   1 
ATOM 3820 C CB  . TRP D 4 71  ? 324.787 348.470 456.364 1.00 101.82 ? 71  TRP B CB  1 
ATOM 3821 C CG  . TRP D 4 71  ? 325.966 349.316 455.972 1.00 101.82 ? 71  TRP B CG  1 
ATOM 3822 C CD1 . TRP D 4 71  ? 327.034 349.663 456.744 1.00 101.82 ? 71  TRP B CD1 1 
ATOM 3823 C CD2 . TRP D 4 71  ? 326.195 349.906 454.690 1.00 101.82 ? 71  TRP B CD2 1 
ATOM 3824 N NE1 . TRP D 4 71  ? 327.903 350.443 456.028 1.00 101.82 ? 71  TRP B NE1 1 
ATOM 3825 C CE2 . TRP D 4 71  ? 327.410 350.603 454.762 1.00 101.82 ? 71  TRP B CE2 1 
ATOM 3826 C CE3 . TRP D 4 71  ? 325.486 349.915 453.491 1.00 101.82 ? 71  TRP B CE3 1 
ATOM 3827 C CZ2 . TRP D 4 71  ? 327.929 351.297 453.686 1.00 101.82 ? 71  TRP B CZ2 1 
ATOM 3828 C CZ3 . TRP D 4 71  ? 326.003 350.604 452.427 1.00 101.82 ? 71  TRP B CZ3 1 
ATOM 3829 C CH2 . TRP D 4 71  ? 327.212 351.286 452.529 1.00 101.82 ? 71  TRP B CH2 1 
ATOM 3830 N N   . MET D 4 72  ? 325.126 349.733 459.690 1.00 111.22 ? 72  MET B N   1 
ATOM 3831 C CA  . MET D 4 72  ? 325.037 350.943 460.488 1.00 111.22 ? 72  MET B CA  1 
ATOM 3832 C C   . MET D 4 72  ? 326.199 351.869 460.143 1.00 111.22 ? 72  MET B C   1 
ATOM 3833 O O   . MET D 4 72  ? 326.948 351.631 459.194 1.00 111.22 ? 72  MET B O   1 
ATOM 3834 C CB  . MET D 4 72  ? 325.002 350.585 461.966 1.00 111.22 ? 72  MET B CB  1 
ATOM 3835 C CG  . MET D 4 72  ? 323.774 349.807 462.350 1.00 111.22 ? 72  MET B CG  1 
ATOM 3836 S SD  . MET D 4 72  ? 323.913 349.022 463.957 1.00 111.22 ? 72  MET B SD  1 
ATOM 3837 C CE  . MET D 4 72  ? 322.214 348.520 464.207 1.00 111.22 ? 72  MET B CE  1 
ATOM 3838 N N   . LYS D 4 73  ? 326.351 352.947 460.914 1.00 107.04 ? 73  LYS B N   1 
ATOM 3839 C CA  . LYS D 4 73  ? 327.428 353.901 460.672 1.00 107.04 ? 73  LYS B CA  1 
ATOM 3840 C C   . LYS D 4 73  ? 328.786 353.297 460.997 1.00 107.04 ? 73  LYS B C   1 
ATOM 3841 O O   . LYS D 4 73  ? 329.722 353.383 460.197 1.00 107.04 ? 73  LYS B O   1 
ATOM 3842 C CB  . LYS D 4 73  ? 327.207 355.159 461.505 1.00 107.04 ? 73  LYS B CB  1 
ATOM 3843 C CG  . LYS D 4 73  ? 326.324 356.201 460.870 1.00 107.04 ? 73  LYS B CG  1 
ATOM 3844 C CD  . LYS D 4 73  ? 326.266 357.438 461.745 1.00 107.04 ? 73  LYS B CD  1 
ATOM 3845 C CE  . LYS D 4 73  ? 325.835 358.658 460.959 1.00 107.04 ? 73  LYS B CE  1 
ATOM 3846 N NZ  . LYS D 4 73  ? 325.853 359.887 461.796 1.00 107.04 ? 73  LYS B NZ  1 
ATOM 3847 N N   . ASN D 4 74  ? 328.916 352.697 462.174 1.00 112.33 ? 74  ASN B N   1 
ATOM 3848 C CA  . ASN D 4 74  ? 330.181 352.107 462.605 1.00 112.33 ? 74  ASN B CA  1 
ATOM 3849 C C   . ASN D 4 74  ? 330.210 350.608 462.309 1.00 112.33 ? 74  ASN B C   1 
ATOM 3850 O O   . ASN D 4 74  ? 330.365 349.774 463.195 1.00 112.33 ? 74  ASN B O   1 
ATOM 3851 C CB  . ASN D 4 74  ? 330.405 352.379 464.085 1.00 112.33 ? 74  ASN B CB  1 
ATOM 3852 C CG  . ASN D 4 74  ? 330.302 353.843 464.426 1.00 112.33 ? 74  ASN B CG  1 
ATOM 3853 O OD1 . ASN D 4 74  ? 331.085 354.659 463.946 1.00 112.33 ? 74  ASN B OD1 1 
ATOM 3854 N ND2 . ASN D 4 74  ? 329.333 354.188 465.263 1.00 112.33 ? 74  ASN B ND2 1 
ATOM 3855 N N   . SER D 4 75  ? 330.056 350.272 461.037 1.00 103.29 ? 75  SER B N   1 
ATOM 3856 C CA  . SER D 4 75  ? 330.096 348.884 460.607 1.00 103.29 ? 75  SER B CA  1 
ATOM 3857 C C   . SER D 4 75  ? 331.476 348.553 460.058 1.00 103.29 ? 75  SER B C   1 
ATOM 3858 O O   . SER D 4 75  ? 332.277 349.439 459.760 1.00 103.29 ? 75  SER B O   1 
ATOM 3859 C CB  . SER D 4 75  ? 329.028 348.611 459.552 1.00 103.29 ? 75  SER B CB  1 
ATOM 3860 O OG  . SER D 4 75  ? 328.774 347.226 459.461 1.00 103.29 ? 75  SER B OG  1 
ATOM 3861 N N   . ALA D 4 76  ? 331.753 347.267 459.941 1.00 102.34 ? 76  ALA B N   1 
ATOM 3862 C CA  . ALA D 4 76  ? 333.091 346.886 459.504 1.00 102.34 ? 76  ALA B CA  1 
ATOM 3863 C C   . ALA D 4 76  ? 333.106 345.910 458.342 1.00 102.34 ? 76  ALA B C   1 
ATOM 3864 O O   . ALA D 4 76  ? 333.990 346.003 457.493 1.00 102.34 ? 76  ALA B O   1 
ATOM 3865 C CB  . ALA D 4 76  ? 333.873 346.293 460.675 1.00 102.34 ? 76  ALA B CB  1 
ATOM 3866 N N   . GLY D 4 77  ? 332.177 344.968 458.292 1.00 95.29  ? 77  GLY B N   1 
ATOM 3867 C CA  . GLY D 4 77  ? 332.154 344.010 457.206 1.00 95.29  ? 77  GLY B CA  1 
ATOM 3868 C C   . GLY D 4 77  ? 331.607 342.678 457.654 1.00 95.29  ? 77  GLY B C   1 
ATOM 3869 O O   . GLY D 4 77  ? 331.458 342.405 458.839 1.00 95.29  ? 77  GLY B O   1 
ATOM 3870 N N   . TRP D 4 78  ? 331.309 341.836 456.667 1.00 96.06  ? 78  TRP B N   1 
ATOM 3871 C CA  . TRP D 4 78  ? 330.747 340.515 456.913 1.00 96.06  ? 78  TRP B CA  1 
ATOM 3872 C C   . TRP D 4 78  ? 331.411 339.518 455.975 1.00 96.06  ? 78  TRP B C   1 
ATOM 3873 O O   . TRP D 4 78  ? 331.924 339.892 454.920 1.00 96.06  ? 78  TRP B O   1 
ATOM 3874 C CB  . TRP D 4 78  ? 329.229 340.497 456.695 1.00 96.06  ? 78  TRP B CB  1 
ATOM 3875 C CG  . TRP D 4 78  ? 328.467 341.544 457.450 1.00 96.06  ? 78  TRP B CG  1 
ATOM 3876 C CD1 . TRP D 4 78  ? 327.825 341.386 458.638 1.00 96.06  ? 78  TRP B CD1 1 
ATOM 3877 C CD2 . TRP D 4 78  ? 328.258 342.906 457.062 1.00 96.06  ? 78  TRP B CD2 1 
ATOM 3878 N NE1 . TRP D 4 78  ? 327.237 342.562 459.019 1.00 96.06  ? 78  TRP B NE1 1 
ATOM 3879 C CE2 . TRP D 4 78  ? 327.487 343.511 458.065 1.00 96.06  ? 78  TRP B CE2 1 
ATOM 3880 C CE3 . TRP D 4 78  ? 328.650 343.672 455.964 1.00 96.06  ? 78  TRP B CE3 1 
ATOM 3881 C CZ2 . TRP D 4 78  ? 327.105 344.843 458.005 1.00 96.06  ? 78  TRP B CZ2 1 
ATOM 3882 C CZ3 . TRP D 4 78  ? 328.266 344.994 455.907 1.00 96.06  ? 78  TRP B CZ3 1 
ATOM 3883 C CH2 . TRP D 4 78  ? 327.502 345.565 456.919 1.00 96.06  ? 78  TRP B CH2 1 
ATOM 3884 N N   . TRP D 4 79  ? 331.395 338.238 456.353 1.00 99.66  ? 79  TRP B N   1 
ATOM 3885 C CA  . TRP D 4 79  ? 331.830 337.210 455.418 1.00 99.66  ? 79  TRP B CA  1 
ATOM 3886 C C   . TRP D 4 79  ? 331.024 335.938 455.632 1.00 99.66  ? 79  TRP B C   1 
ATOM 3887 O O   . TRP D 4 79  ? 330.655 335.613 456.760 1.00 99.66  ? 79  TRP B O   1 
ATOM 3888 C CB  . TRP D 4 79  ? 333.333 336.894 455.522 1.00 99.66  ? 79  TRP B CB  1 
ATOM 3889 C CG  . TRP D 4 79  ? 333.804 336.067 456.695 1.00 99.66  ? 79  TRP B CG  1 
ATOM 3890 C CD1 . TRP D 4 79  ? 333.821 334.705 456.775 1.00 99.66  ? 79  TRP B CD1 1 
ATOM 3891 C CD2 . TRP D 4 79  ? 334.409 336.539 457.901 1.00 99.66  ? 79  TRP B CD2 1 
ATOM 3892 N NE1 . TRP D 4 79  ? 334.349 334.306 457.972 1.00 99.66  ? 79  TRP B NE1 1 
ATOM 3893 C CE2 . TRP D 4 79  ? 334.723 335.414 458.678 1.00 99.66  ? 79  TRP B CE2 1 
ATOM 3894 C CE3 . TRP D 4 79  ? 334.694 337.804 458.409 1.00 99.66  ? 79  TRP B CE3 1 
ATOM 3895 C CZ2 . TRP D 4 79  ? 335.306 335.512 459.934 1.00 99.66  ? 79  TRP B CZ2 1 
ATOM 3896 C CZ3 . TRP D 4 79  ? 335.274 337.902 459.659 1.00 99.66  ? 79  TRP B CZ3 1 
ATOM 3897 C CH2 . TRP D 4 79  ? 335.575 336.764 460.406 1.00 99.66  ? 79  TRP B CH2 1 
ATOM 3898 N N   . TRP D 4 80  ? 330.775 335.214 454.543 1.00 97.99  ? 80  TRP B N   1 
ATOM 3899 C CA  . TRP D 4 80  ? 330.109 333.917 454.581 1.00 97.99  ? 80  TRP B CA  1 
ATOM 3900 C C   . TRP D 4 80  ? 331.003 332.902 453.890 1.00 97.99  ? 80  TRP B C   1 
ATOM 3901 O O   . TRP D 4 80  ? 331.691 333.243 452.925 1.00 97.99  ? 80  TRP B O   1 
ATOM 3902 C CB  . TRP D 4 80  ? 328.754 333.953 453.872 1.00 97.99  ? 80  TRP B CB  1 
ATOM 3903 C CG  . TRP D 4 80  ? 327.675 334.744 454.516 1.00 97.99  ? 80  TRP B CG  1 
ATOM 3904 C CD1 . TRP D 4 80  ? 326.759 334.294 455.410 1.00 97.99  ? 80  TRP B CD1 1 
ATOM 3905 C CD2 . TRP D 4 80  ? 327.355 336.113 454.269 1.00 97.99  ? 80  TRP B CD2 1 
ATOM 3906 N NE1 . TRP D 4 80  ? 325.902 335.303 455.758 1.00 97.99  ? 80  TRP B NE1 1 
ATOM 3907 C CE2 . TRP D 4 80  ? 326.249 336.432 455.068 1.00 97.99  ? 80  TRP B CE2 1 
ATOM 3908 C CE3 . TRP D 4 80  ? 327.908 337.104 453.459 1.00 97.99  ? 80  TRP B CE3 1 
ATOM 3909 C CZ2 . TRP D 4 80  ? 325.681 337.696 455.080 1.00 97.99  ? 80  TRP B CZ2 1 
ATOM 3910 C CZ3 . TRP D 4 80  ? 327.346 338.359 453.475 1.00 97.99  ? 80  TRP B CZ3 1 
ATOM 3911 C CH2 . TRP D 4 80  ? 326.247 338.646 454.281 1.00 97.99  ? 80  TRP B CH2 1 
ATOM 3912 N N   . LYS D 4 81  ? 330.988 331.662 454.367 1.00 98.26  ? 81  LYS B N   1 
ATOM 3913 C CA  . LYS D 4 81  ? 331.603 330.567 453.630 1.00 98.26  ? 81  LYS B CA  1 
ATOM 3914 C C   . LYS D 4 81  ? 330.531 329.880 452.803 1.00 98.26  ? 81  LYS B C   1 
ATOM 3915 O O   . LYS D 4 81  ? 329.480 329.511 453.332 1.00 98.26  ? 81  LYS B O   1 
ATOM 3916 C CB  . LYS D 4 81  ? 332.260 329.576 454.582 1.00 98.26  ? 81  LYS B CB  1 
ATOM 3917 C CG  . LYS D 4 81  ? 333.390 330.165 455.385 1.00 98.26  ? 81  LYS B CG  1 
ATOM 3918 C CD  . LYS D 4 81  ? 334.638 330.306 454.566 1.00 98.26  ? 81  LYS B CD  1 
ATOM 3919 C CE  . LYS D 4 81  ? 335.770 330.786 455.430 1.00 98.26  ? 81  LYS B CE  1 
ATOM 3920 N NZ  . LYS D 4 81  ? 337.045 330.793 454.685 1.00 98.26  ? 81  LYS B NZ  1 
ATOM 3921 N N   . LEU D 4 82  ? 330.789 329.704 451.512 1.00 104.31 ? 82  LEU B N   1 
ATOM 3922 C CA  . LEU D 4 82  ? 329.658 329.464 450.625 1.00 104.31 ? 82  LEU B CA  1 
ATOM 3923 C C   . LEU D 4 82  ? 329.108 328.037 450.599 1.00 104.31 ? 82  LEU B C   1 
ATOM 3924 O O   . LEU D 4 82  ? 327.880 327.894 450.639 1.00 104.31 ? 82  LEU B O   1 
ATOM 3925 C CB  . LEU D 4 82  ? 329.974 329.927 449.205 1.00 104.31 ? 82  LEU B CB  1 
ATOM 3926 C CG  . LEU D 4 82  ? 328.711 330.243 448.405 1.00 104.31 ? 82  LEU B CG  1 
ATOM 3927 C CD1 . LEU D 4 82  ? 327.706 331.042 449.218 1.00 104.31 ? 82  LEU B CD1 1 
ATOM 3928 C CD2 . LEU D 4 82  ? 329.082 331.005 447.167 1.00 104.31 ? 82  LEU B CD2 1 
ATOM 3929 N N   . PRO D 4 83  ? 329.908 326.938 450.530 1.00 103.64 ? 83  PRO B N   1 
ATOM 3930 C CA  . PRO D 4 83  ? 329.267 325.630 450.722 1.00 103.64 ? 83  PRO B CA  1 
ATOM 3931 C C   . PRO D 4 83  ? 329.207 325.220 452.183 1.00 103.64 ? 83  PRO B C   1 
ATOM 3932 O O   . PRO D 4 83  ? 329.448 324.060 452.523 1.00 103.64 ? 83  PRO B O   1 
ATOM 3933 C CB  . PRO D 4 83  ? 330.152 324.689 449.907 1.00 103.64 ? 83  PRO B CB  1 
ATOM 3934 C CG  . PRO D 4 83  ? 331.474 325.265 450.044 1.00 103.64 ? 83  PRO B CG  1 
ATOM 3935 C CD  . PRO D 4 83  ? 331.323 326.760 450.152 1.00 103.64 ? 83  PRO B CD  1 
ATOM 3936 N N   . ASP D 4 84  ? 328.885 326.176 453.051 1.00 111.85 ? 84  ASP B N   1 
ATOM 3937 C CA  . ASP D 4 84  ? 328.694 325.958 454.474 1.00 111.85 ? 84  ASP B CA  1 
ATOM 3938 C C   . ASP D 4 84  ? 327.426 326.695 454.875 1.00 111.85 ? 84  ASP B C   1 
ATOM 3939 O O   . ASP D 4 84  ? 326.723 326.298 455.807 1.00 111.85 ? 84  ASP B O   1 
ATOM 3940 C CB  . ASP D 4 84  ? 329.909 326.468 455.251 1.00 111.85 ? 84  ASP B CB  1 
ATOM 3941 C CG  . ASP D 4 84  ? 330.046 325.846 456.630 1.00 111.85 ? 84  ASP B CG  1 
ATOM 3942 O OD1 . ASP D 4 84  ? 329.027 325.506 457.259 1.00 111.85 ? 84  ASP B OD1 1 
ATOM 3943 O OD2 . ASP D 4 84  ? 331.195 325.702 457.093 1.00 111.85 ? 84  ASP B OD2 1 
ATOM 3944 N N   . ALA D 4 85  ? 327.117 327.767 454.143 1.00 112.86 ? 85  ALA B N   1 
ATOM 3945 C CA  . ALA D 4 85  ? 325.979 328.604 454.496 1.00 112.86 ? 85  ALA B CA  1 
ATOM 3946 C C   . ALA D 4 85  ? 324.662 327.948 454.121 1.00 112.86 ? 85  ALA B C   1 
ATOM 3947 O O   . ALA D 4 85  ? 323.637 328.215 454.755 1.00 112.86 ? 85  ALA B O   1 
ATOM 3948 C CB  . ALA D 4 85  ? 326.103 329.967 453.823 1.00 112.86 ? 85  ALA B CB  1 
ATOM 3949 N N   . LEU D 4 86  ? 324.667 327.092 453.102 1.00 113.13 ? 86  LEU B N   1 
ATOM 3950 C CA  . LEU D 4 86  ? 323.479 326.363 452.685 1.00 113.13 ? 86  LEU B CA  1 
ATOM 3951 C C   . LEU D 4 86  ? 323.456 324.943 453.235 1.00 113.13 ? 86  LEU B C   1 
ATOM 3952 O O   . LEU D 4 86  ? 322.890 324.044 452.607 1.00 113.13 ? 86  LEU B O   1 
ATOM 3953 C CB  . LEU D 4 86  ? 323.382 326.344 451.161 1.00 113.13 ? 86  LEU B CB  1 
ATOM 3954 C CG  . LEU D 4 86  ? 323.597 327.674 450.447 1.00 113.13 ? 86  LEU B CG  1 
ATOM 3955 C CD1 . LEU D 4 86  ? 323.550 327.475 448.958 1.00 113.13 ? 86  LEU B CD1 1 
ATOM 3956 C CD2 . LEU D 4 86  ? 322.548 328.666 450.863 1.00 113.13 ? 86  LEU B CD2 1 
ATOM 3957 N N   . SER D 4 87  ? 324.064 324.721 454.396 1.00 119.26 ? 87  SER B N   1 
ATOM 3958 C CA  . SER D 4 87  ? 324.150 323.386 454.967 1.00 119.26 ? 87  SER B CA  1 
ATOM 3959 C C   . SER D 4 87  ? 322.891 322.967 455.708 1.00 119.26 ? 87  SER B C   1 
ATOM 3960 O O   . SER D 4 87  ? 322.686 321.768 455.913 1.00 119.26 ? 87  SER B O   1 
ATOM 3961 C CB  . SER D 4 87  ? 325.343 323.294 455.916 1.00 119.26 ? 87  SER B CB  1 
ATOM 3962 O OG  . SER D 4 87  ? 325.218 324.231 456.966 1.00 119.26 ? 87  SER B OG  1 
ATOM 3963 N N   . GLN D 4 88  ? 322.053 323.915 456.125 1.00 121.64 ? 88  GLN B N   1 
ATOM 3964 C CA  . GLN D 4 88  ? 320.754 323.603 456.707 1.00 121.64 ? 88  GLN B CA  1 
ATOM 3965 C C   . GLN D 4 88  ? 319.615 324.104 455.832 1.00 121.64 ? 88  GLN B C   1 
ATOM 3966 O O   . GLN D 4 88  ? 318.469 324.165 456.281 1.00 121.64 ? 88  GLN B O   1 
ATOM 3967 C CB  . GLN D 4 88  ? 320.620 324.184 458.116 1.00 121.64 ? 88  GLN B CB  1 
ATOM 3968 C CG  . GLN D 4 88  ? 321.346 323.410 459.201 1.00 121.64 ? 88  GLN B CG  1 
ATOM 3969 C CD  . GLN D 4 88  ? 322.839 323.625 459.183 1.00 121.64 ? 88  GLN B CD  1 
ATOM 3970 O OE1 . GLN D 4 88  ? 323.611 322.692 458.973 1.00 121.64 ? 88  GLN B OE1 1 
ATOM 3971 N NE2 . GLN D 4 88  ? 323.258 324.861 459.413 1.00 121.64 ? 88  GLN B NE2 1 
ATOM 3972 N N   . MET D 4 89  ? 319.909 324.456 454.589 1.00 120.07 ? 89  MET B N   1 
ATOM 3973 C CA  . MET D 4 89  ? 318.941 325.117 453.721 1.00 120.07 ? 89  MET B CA  1 
ATOM 3974 C C   . MET D 4 89  ? 318.208 324.101 452.850 1.00 120.07 ? 89  MET B C   1 
ATOM 3975 O O   . MET D 4 89  ? 318.545 323.874 451.692 1.00 120.07 ? 89  MET B O   1 
ATOM 3976 C CB  . MET D 4 89  ? 319.637 326.174 452.872 1.00 120.07 ? 89  MET B CB  1 
ATOM 3977 C CG  . MET D 4 89  ? 319.943 327.454 453.615 1.00 120.07 ? 89  MET B CG  1 
ATOM 3978 S SD  . MET D 4 89  ? 318.445 328.333 454.068 1.00 120.07 ? 89  MET B SD  1 
ATOM 3979 C CE  . MET D 4 89  ? 319.115 329.616 455.113 1.00 120.07 ? 89  MET B CE  1 
ATOM 3980 N N   . GLY D 4 90  ? 317.189 323.482 453.438 1.00 123.65 ? 90  GLY B N   1 
ATOM 3981 C CA  . GLY D 4 90  ? 316.263 322.693 452.644 1.00 123.65 ? 90  GLY B CA  1 
ATOM 3982 C C   . GLY D 4 90  ? 316.855 321.367 452.216 1.00 123.65 ? 90  GLY B C   1 
ATOM 3983 O O   . GLY D 4 90  ? 317.564 320.700 452.975 1.00 123.65 ? 90  GLY B O   1 
ATOM 3984 N N   . LEU D 4 91  ? 316.569 320.980 450.976 1.00 124.50 ? 91  LEU B N   1 
ATOM 3985 C CA  . LEU D 4 91  ? 317.030 319.697 450.468 1.00 124.50 ? 91  LEU B CA  1 
ATOM 3986 C C   . LEU D 4 91  ? 318.498 319.731 450.077 1.00 124.50 ? 91  LEU B C   1 
ATOM 3987 O O   . LEU D 4 91  ? 319.130 318.671 450.014 1.00 124.50 ? 91  LEU B O   1 
ATOM 3988 C CB  . LEU D 4 91  ? 316.154 319.265 449.286 1.00 124.50 ? 91  LEU B CB  1 
ATOM 3989 C CG  . LEU D 4 91  ? 316.245 317.841 448.724 1.00 124.50 ? 91  LEU B CG  1 
ATOM 3990 C CD1 . LEU D 4 91  ? 314.865 317.372 448.313 1.00 124.50 ? 91  LEU B CD1 1 
ATOM 3991 C CD2 . LEU D 4 91  ? 317.199 317.725 447.540 1.00 124.50 ? 91  LEU B CD2 1 
ATOM 3992 N N   . PHE D 4 92  ? 319.066 320.915 449.863 1.00 120.59 ? 92  PHE B N   1 
ATOM 3993 C CA  . PHE D 4 92  ? 320.496 321.034 449.625 1.00 120.59 ? 92  PHE B CA  1 
ATOM 3994 C C   . PHE D 4 92  ? 321.313 320.637 450.842 1.00 120.59 ? 92  PHE B C   1 
ATOM 3995 O O   . PHE D 4 92  ? 322.445 320.168 450.693 1.00 120.59 ? 92  PHE B O   1 
ATOM 3996 C CB  . PHE D 4 92  ? 320.849 322.463 449.218 1.00 120.59 ? 92  PHE B CB  1 
ATOM 3997 C CG  . PHE D 4 92  ? 322.229 322.608 448.665 1.00 120.59 ? 92  PHE B CG  1 
ATOM 3998 C CD1 . PHE D 4 92  ? 322.499 322.262 447.356 1.00 120.59 ? 92  PHE B CD1 1 
ATOM 3999 C CD2 . PHE D 4 92  ? 323.255 323.093 449.452 1.00 120.59 ? 92  PHE B CD2 1 
ATOM 4000 C CE1 . PHE D 4 92  ? 323.766 322.398 446.843 1.00 120.59 ? 92  PHE B CE1 1 
ATOM 4001 C CE2 . PHE D 4 92  ? 324.525 323.227 448.944 1.00 120.59 ? 92  PHE B CE2 1 
ATOM 4002 C CZ  . PHE D 4 92  ? 324.779 322.881 447.639 1.00 120.59 ? 92  PHE B CZ  1 
ATOM 4003 N N   . GLY D 4 93  ? 320.764 320.802 452.040 1.00 124.64 ? 93  GLY B N   1 
ATOM 4004 C CA  . GLY D 4 93  ? 321.390 320.245 453.218 1.00 124.64 ? 93  GLY B CA  1 
ATOM 4005 C C   . GLY D 4 93  ? 321.246 318.752 453.355 1.00 124.64 ? 93  GLY B C   1 
ATOM 4006 O O   . GLY D 4 93  ? 322.038 318.128 454.065 1.00 124.64 ? 93  GLY B O   1 
ATOM 4007 N N   . GLN D 4 94  ? 320.252 318.159 452.693 1.00 126.39 ? 94  GLN B N   1 
ATOM 4008 C CA  . GLN D 4 94  ? 320.116 316.710 452.709 1.00 126.39 ? 94  GLN B CA  1 
ATOM 4009 C C   . GLN D 4 94  ? 321.061 316.046 451.723 1.00 126.39 ? 94  GLN B C   1 
ATOM 4010 O O   . GLN D 4 94  ? 321.539 314.938 451.981 1.00 126.39 ? 94  GLN B O   1 
ATOM 4011 C CB  . GLN D 4 94  ? 318.677 316.303 452.397 1.00 126.39 ? 94  GLN B CB  1 
ATOM 4012 C CG  . GLN D 4 94  ? 317.629 317.069 453.172 1.00 126.39 ? 94  GLN B CG  1 
ATOM 4013 C CD  . GLN D 4 94  ? 317.916 317.096 454.654 1.00 126.39 ? 94  GLN B CD  1 
ATOM 4014 O OE1 . GLN D 4 94  ? 318.040 316.052 455.292 1.00 126.39 ? 94  GLN B OE1 1 
ATOM 4015 N NE2 . GLN D 4 94  ? 318.027 318.295 455.213 1.00 126.39 ? 94  GLN B NE2 1 
ATOM 4016 N N   . ASN D 4 95  ? 321.344 316.698 450.597 1.00 125.01 ? 95  ASN B N   1 
ATOM 4017 C CA  . ASN D 4 95  ? 322.285 316.132 449.644 1.00 125.01 ? 95  ASN B CA  1 
ATOM 4018 C C   . ASN D 4 95  ? 323.727 316.310 450.088 1.00 125.01 ? 95  ASN B C   1 
ATOM 4019 O O   . ASN D 4 95  ? 324.609 315.619 449.572 1.00 125.01 ? 95  ASN B O   1 
ATOM 4020 C CB  . ASN D 4 95  ? 322.079 316.758 448.270 1.00 125.01 ? 95  ASN B CB  1 
ATOM 4021 C CG  . ASN D 4 95  ? 320.795 316.311 447.625 1.00 125.01 ? 95  ASN B CG  1 
ATOM 4022 O OD1 . ASN D 4 95  ? 319.973 315.652 448.255 1.00 125.01 ? 95  ASN B OD1 1 
ATOM 4023 N ND2 . ASN D 4 95  ? 320.611 316.664 446.361 1.00 125.01 ? 95  ASN B ND2 1 
ATOM 4024 N N   . MET D 4 96  ? 323.989 317.217 451.027 1.00 125.42 ? 96  MET B N   1 
ATOM 4025 C CA  . MET D 4 96  ? 325.345 317.361 451.539 1.00 125.42 ? 96  MET B CA  1 
ATOM 4026 C C   . MET D 4 96  ? 325.700 316.241 452.504 1.00 125.42 ? 96  MET B C   1 
ATOM 4027 O O   . MET D 4 96  ? 326.868 315.851 452.591 1.00 125.42 ? 96  MET B O   1 
ATOM 4028 C CB  . MET D 4 96  ? 325.513 318.717 452.219 1.00 125.42 ? 96  MET B CB  1 
ATOM 4029 C CG  . MET D 4 96  ? 325.946 319.823 451.283 1.00 125.42 ? 96  MET B CG  1 
ATOM 4030 S SD  . MET D 4 96  ? 326.128 321.407 452.116 1.00 125.42 ? 96  MET B SD  1 
ATOM 4031 C CE  . MET D 4 96  ? 327.217 320.957 453.460 1.00 125.42 ? 96  MET B CE  1 
ATOM 4032 N N   . GLN D 4 97  ? 324.717 315.712 453.231 1.00 125.81 ? 97  GLN B N   1 
ATOM 4033 C CA  . GLN D 4 97  ? 325.004 314.685 454.225 1.00 125.81 ? 97  GLN B CA  1 
ATOM 4034 C C   . GLN D 4 97  ? 324.851 313.284 453.654 1.00 125.81 ? 97  GLN B C   1 
ATOM 4035 O O   . GLN D 4 97  ? 325.566 312.364 454.062 1.00 125.81 ? 97  GLN B O   1 
ATOM 4036 C CB  . GLN D 4 97  ? 324.088 314.854 455.431 1.00 125.81 ? 97  GLN B CB  1 
ATOM 4037 C CG  . GLN D 4 97  ? 324.122 316.236 456.029 1.00 125.81 ? 97  GLN B CG  1 
ATOM 4038 C CD  . GLN D 4 97  ? 323.058 316.431 457.079 1.00 125.81 ? 97  GLN B CD  1 
ATOM 4039 O OE1 . GLN D 4 97  ? 322.250 315.540 457.332 1.00 125.81 ? 97  GLN B OE1 1 
ATOM 4040 N NE2 . GLN D 4 97  ? 323.049 317.604 457.700 1.00 125.81 ? 97  GLN B NE2 1 
ATOM 4041 N N   . TYR D 4 98  ? 323.922 313.098 452.722 1.00 129.46 ? 98  TYR B N   1 
ATOM 4042 C CA  . TYR D 4 98  ? 323.644 311.759 452.217 1.00 129.46 ? 98  TYR B CA  1 
ATOM 4043 C C   . TYR D 4 98  ? 324.651 311.354 451.149 1.00 129.46 ? 98  TYR B C   1 
ATOM 4044 O O   . TYR D 4 98  ? 324.987 310.173 451.020 1.00 129.46 ? 98  TYR B O   1 
ATOM 4045 C CB  . TYR D 4 98  ? 322.218 311.690 451.673 1.00 129.46 ? 98  TYR B CB  1 
ATOM 4046 C CG  . TYR D 4 98  ? 321.176 311.345 452.714 1.00 129.46 ? 98  TYR B CG  1 
ATOM 4047 C CD1 . TYR D 4 98  ? 321.166 311.974 453.955 1.00 129.46 ? 98  TYR B CD1 1 
ATOM 4048 C CD2 . TYR D 4 98  ? 320.207 310.385 452.459 1.00 129.46 ? 98  TYR B CD2 1 
ATOM 4049 C CE1 . TYR D 4 98  ? 320.220 311.662 454.909 1.00 129.46 ? 98  TYR B CE1 1 
ATOM 4050 C CE2 . TYR D 4 98  ? 319.251 310.066 453.409 1.00 129.46 ? 98  TYR B CE2 1 
ATOM 4051 C CZ  . TYR D 4 98  ? 319.266 310.708 454.631 1.00 129.46 ? 98  TYR B CZ  1 
ATOM 4052 O OH  . TYR D 4 98  ? 318.322 310.396 455.580 1.00 129.46 ? 98  TYR B OH  1 
ATOM 4053 N N   . HIS D 4 99  ? 325.139 312.317 450.375 1.00 126.62 ? 99  HIS B N   1 
ATOM 4054 C CA  . HIS D 4 99  ? 326.147 312.054 449.362 1.00 126.62 ? 99  HIS B CA  1 
ATOM 4055 C C   . HIS D 4 99  ? 327.522 312.461 449.871 1.00 126.62 ? 99  HIS B C   1 
ATOM 4056 O O   . HIS D 4 99  ? 327.649 313.367 450.698 1.00 126.62 ? 99  HIS B O   1 
ATOM 4057 C CB  . HIS D 4 99  ? 325.822 312.799 448.072 1.00 126.62 ? 99  HIS B CB  1 
ATOM 4058 C CG  . HIS D 4 99  ? 324.648 312.240 447.336 1.00 126.62 ? 99  HIS B CG  1 
ATOM 4059 N ND1 . HIS D 4 99  ? 323.368 312.280 447.840 1.00 126.62 ? 99  HIS B ND1 1 
ATOM 4060 C CD2 . HIS D 4 99  ? 324.560 311.621 446.137 1.00 126.62 ? 99  HIS B CD2 1 
ATOM 4061 C CE1 . HIS D 4 99  ? 322.540 311.716 446.980 1.00 126.62 ? 99  HIS B CE1 1 
ATOM 4062 N NE2 . HIS D 4 99  ? 323.238 311.309 445.937 1.00 126.62 ? 99  HIS B NE2 1 
ATOM 4063 N N   . TYR D 4 100 ? 328.554 311.785 449.366 1.00 130.96 ? 100 TYR B N   1 
ATOM 4064 C CA  . TYR D 4 100 ? 329.903 311.988 449.880 1.00 130.96 ? 100 TYR B CA  1 
ATOM 4065 C C   . TYR D 4 100 ? 330.620 313.108 449.134 1.00 130.96 ? 100 TYR B C   1 
ATOM 4066 O O   . TYR D 4 100 ? 331.197 314.004 449.757 1.00 130.96 ? 100 TYR B O   1 
ATOM 4067 C CB  . TYR D 4 100 ? 330.688 310.678 449.794 1.00 130.96 ? 100 TYR B CB  1 
ATOM 4068 C CG  . TYR D 4 100 ? 331.958 310.651 450.608 1.00 130.96 ? 100 TYR B CG  1 
ATOM 4069 C CD1 . TYR D 4 100 ? 331.917 310.727 451.995 1.00 130.96 ? 100 TYR B CD1 1 
ATOM 4070 C CD2 . TYR D 4 100 ? 333.196 310.514 449.997 1.00 130.96 ? 100 TYR B CD2 1 
ATOM 4071 C CE1 . TYR D 4 100 ? 333.078 310.694 452.750 1.00 130.96 ? 100 TYR B CE1 1 
ATOM 4072 C CE2 . TYR D 4 100 ? 334.364 310.478 450.743 1.00 130.96 ? 100 TYR B CE2 1 
ATOM 4073 C CZ  . TYR D 4 100 ? 334.297 310.568 452.118 1.00 130.96 ? 100 TYR B CZ  1 
ATOM 4074 O OH  . TYR D 4 100 ? 335.451 310.533 452.864 1.00 130.96 ? 100 TYR B OH  1 
ATOM 4075 N N   . LEU D 4 101 ? 330.592 313.077 447.808 1.00 121.97 ? 101 LEU B N   1 
ATOM 4076 C CA  . LEU D 4 101 ? 331.257 314.065 446.968 1.00 121.97 ? 101 LEU B CA  1 
ATOM 4077 C C   . LEU D 4 101 ? 330.222 314.975 446.316 1.00 121.97 ? 101 LEU B C   1 
ATOM 4078 O O   . LEU D 4 101 ? 329.024 314.875 446.576 1.00 121.97 ? 101 LEU B O   1 
ATOM 4079 C CB  . LEU D 4 101 ? 332.124 313.380 445.912 1.00 121.97 ? 101 LEU B CB  1 
ATOM 4080 C CG  . LEU D 4 101 ? 333.125 312.342 446.414 1.00 121.97 ? 101 LEU B CG  1 
ATOM 4081 C CD1 . LEU D 4 101 ? 333.923 311.790 445.258 1.00 121.97 ? 101 LEU B CD1 1 
ATOM 4082 C CD2 . LEU D 4 101 ? 334.044 312.953 447.443 1.00 121.97 ? 101 LEU B CD2 1 
ATOM 4083 N N   . GLY D 4 102 ? 330.692 315.866 445.467 1.00 116.91 ? 102 GLY B N   1 
ATOM 4084 C CA  . GLY D 4 102 ? 329.819 316.760 444.732 1.00 116.91 ? 102 GLY B CA  1 
ATOM 4085 C C   . GLY D 4 102 ? 330.524 318.033 444.301 1.00 116.91 ? 102 GLY B C   1 
ATOM 4086 O O   . GLY D 4 102 ? 331.537 318.445 444.849 1.00 116.91 ? 102 GLY B O   1 
ATOM 4087 N N   . ARG D 4 103 ? 329.968 318.674 443.277 1.00 116.83 ? 103 ARG B N   1 
ATOM 4088 C CA  . ARG D 4 103 ? 330.458 319.946 442.775 1.00 116.83 ? 103 ARG B CA  1 
ATOM 4089 C C   . ARG D 4 103 ? 329.283 320.845 442.420 1.00 116.83 ? 103 ARG B C   1 
ATOM 4090 O O   . ARG D 4 103 ? 328.246 320.382 441.942 1.00 116.83 ? 103 ARG B O   1 
ATOM 4091 C CB  . ARG D 4 103 ? 331.347 319.753 441.548 1.00 116.83 ? 103 ARG B CB  1 
ATOM 4092 C CG  . ARG D 4 103 ? 330.750 318.840 440.506 1.00 116.83 ? 103 ARG B CG  1 
ATOM 4093 C CD  . ARG D 4 103 ? 331.669 318.697 439.320 1.00 116.83 ? 103 ARG B CD  1 
ATOM 4094 N NE  . ARG D 4 103 ? 331.745 319.927 438.547 1.00 116.83 ? 103 ARG B NE  1 
ATOM 4095 C CZ  . ARG D 4 103 ? 332.746 320.227 437.732 1.00 116.83 ? 103 ARG B CZ  1 
ATOM 4096 N NH1 . ARG D 4 103 ? 333.753 319.384 437.588 1.00 116.83 ? 103 ARG B NH1 1 
ATOM 4097 N NH2 . ARG D 4 103 ? 332.740 321.366 437.060 1.00 116.83 ? 103 ARG B NH2 1 
ATOM 4098 N N   . THR D 4 104 ? 329.443 322.144 442.670 1.00 115.65 ? 104 THR B N   1 
ATOM 4099 C CA  . THR D 4 104 ? 328.379 323.110 442.430 1.00 115.65 ? 104 THR B CA  1 
ATOM 4100 C C   . THR D 4 104 ? 328.950 324.374 441.809 1.00 115.65 ? 104 THR B C   1 
ATOM 4101 O O   . THR D 4 104 ? 330.153 324.630 441.874 1.00 115.65 ? 104 THR B O   1 
ATOM 4102 C CB  . THR D 4 104 ? 327.634 323.516 443.713 1.00 115.65 ? 104 THR B CB  1 
ATOM 4103 O OG1 . THR D 4 104 ? 328.569 324.036 444.665 1.00 115.65 ? 104 THR B OG1 1 
ATOM 4104 C CG2 . THR D 4 104 ? 326.855 322.365 444.331 1.00 115.65 ? 104 THR B CG2 1 
ATOM 4105 N N   . GLY D 4 105 ? 328.061 325.157 441.198 1.00 115.23 ? 105 GLY B N   1 
ATOM 4106 C CA  . GLY D 4 105 ? 328.301 326.547 440.891 1.00 115.23 ? 105 GLY B CA  1 
ATOM 4107 C C   . GLY D 4 105 ? 327.326 327.416 441.670 1.00 115.23 ? 105 GLY B C   1 
ATOM 4108 O O   . GLY D 4 105 ? 326.466 326.929 442.395 1.00 115.23 ? 105 GLY B O   1 
ATOM 4109 N N   . TYR D 4 106 ? 327.473 328.729 441.513 1.00 109.34 ? 106 TYR B N   1 
ATOM 4110 C CA  . TYR D 4 106 ? 326.668 329.640 442.314 1.00 109.34 ? 106 TYR B CA  1 
ATOM 4111 C C   . TYR D 4 106 ? 326.222 330.835 441.485 1.00 109.34 ? 106 TYR B C   1 
ATOM 4112 O O   . TYR D 4 106 ? 326.775 331.128 440.425 1.00 109.34 ? 106 TYR B O   1 
ATOM 4113 C CB  . TYR D 4 106 ? 327.431 330.105 443.550 1.00 109.34 ? 106 TYR B CB  1 
ATOM 4114 C CG  . TYR D 4 106 ? 327.636 329.010 444.558 1.00 109.34 ? 106 TYR B CG  1 
ATOM 4115 C CD1 . TYR D 4 106 ? 326.606 328.611 445.390 1.00 109.34 ? 106 TYR B CD1 1 
ATOM 4116 C CD2 . TYR D 4 106 ? 328.854 328.359 444.662 1.00 109.34 ? 106 TYR B CD2 1 
ATOM 4117 C CE1 . TYR D 4 106 ? 326.785 327.606 446.306 1.00 109.34 ? 106 TYR B CE1 1 
ATOM 4118 C CE2 . TYR D 4 106 ? 329.044 327.354 445.578 1.00 109.34 ? 106 TYR B CE2 1 
ATOM 4119 C CZ  . TYR D 4 106 ? 328.005 326.982 446.395 1.00 109.34 ? 106 TYR B CZ  1 
ATOM 4120 O OH  . TYR D 4 106 ? 328.188 325.976 447.308 1.00 109.34 ? 106 TYR B OH  1 
ATOM 4121 N N   . THR D 4 107 ? 325.202 331.522 441.996 1.00 104.68 ? 107 THR B N   1 
ATOM 4122 C CA  . THR D 4 107 ? 324.694 332.759 441.408 1.00 104.68 ? 107 THR B CA  1 
ATOM 4123 C C   . THR D 4 107 ? 324.260 333.647 442.561 1.00 104.68 ? 107 THR B C   1 
ATOM 4124 O O   . THR D 4 107 ? 323.197 333.424 443.141 1.00 104.68 ? 107 THR B O   1 
ATOM 4125 C CB  . THR D 4 107 ? 323.531 332.494 440.466 1.00 104.68 ? 107 THR B CB  1 
ATOM 4126 O OG1 . THR D 4 107 ? 323.964 331.638 439.407 1.00 104.68 ? 107 THR B OG1 1 
ATOM 4127 C CG2 . THR D 4 107 ? 323.025 333.790 439.876 1.00 104.68 ? 107 THR B CG2 1 
ATOM 4128 N N   . ILE D 4 108 ? 325.073 334.640 442.897 1.00 94.44  ? 108 ILE B N   1 
ATOM 4129 C CA  . ILE D 4 108 ? 324.903 335.421 444.114 1.00 94.44  ? 108 ILE B CA  1 
ATOM 4130 C C   . ILE D 4 108 ? 324.258 336.749 443.761 1.00 94.44  ? 108 ILE B C   1 
ATOM 4131 O O   . ILE D 4 108 ? 324.771 337.486 442.916 1.00 94.44  ? 108 ILE B O   1 
ATOM 4132 C CB  . ILE D 4 108 ? 326.247 335.637 444.822 1.00 94.44  ? 108 ILE B CB  1 
ATOM 4133 C CG1 . ILE D 4 108 ? 326.876 334.293 445.173 1.00 94.44  ? 108 ILE B CG1 1 
ATOM 4134 C CG2 . ILE D 4 108 ? 326.058 336.468 446.059 1.00 94.44  ? 108 ILE B CG2 1 
ATOM 4135 C CD1 . ILE D 4 108 ? 328.264 334.404 445.727 1.00 94.44  ? 108 ILE B CD1 1 
ATOM 4136 N N   . HIS D 4 109 ? 323.137 337.053 444.408 1.00 99.85  ? 109 HIS B N   1 
ATOM 4137 C CA  . HIS D 4 109 ? 322.435 338.321 444.238 1.00 99.85  ? 109 HIS B CA  1 
ATOM 4138 C C   . HIS D 4 109 ? 322.533 339.096 445.542 1.00 99.85  ? 109 HIS B C   1 
ATOM 4139 O O   . HIS D 4 109 ? 322.010 338.654 446.569 1.00 99.85  ? 109 HIS B O   1 
ATOM 4140 C CB  . HIS D 4 109 ? 320.973 338.100 443.864 1.00 99.85  ? 109 HIS B CB  1 
ATOM 4141 C CG  . HIS D 4 109 ? 320.752 337.809 442.416 1.00 99.85  ? 109 HIS B CG  1 
ATOM 4142 N ND1 . HIS D 4 109 ? 320.594 336.530 441.932 1.00 99.85  ? 109 HIS B ND1 1 
ATOM 4143 C CD2 . HIS D 4 109 ? 320.645 338.632 441.348 1.00 99.85  ? 109 HIS B CD2 1 
ATOM 4144 C CE1 . HIS D 4 109 ? 320.407 336.576 440.626 1.00 99.85  ? 109 HIS B CE1 1 
ATOM 4145 N NE2 . HIS D 4 109 ? 320.435 337.840 440.246 1.00 99.85  ? 109 HIS B NE2 1 
ATOM 4146 N N   . VAL D 4 110 ? 323.193 340.247 445.506 1.00 95.02  ? 110 VAL B N   1 
ATOM 4147 C CA  . VAL D 4 110 ? 323.285 341.146 446.648 1.00 95.02  ? 110 VAL B CA  1 
ATOM 4148 C C   . VAL D 4 110 ? 322.542 342.422 446.297 1.00 95.02  ? 110 VAL B C   1 
ATOM 4149 O O   . VAL D 4 110 ? 322.785 343.010 445.239 1.00 95.02  ? 110 VAL B O   1 
ATOM 4150 C CB  . VAL D 4 110 ? 324.746 341.451 447.007 1.00 95.02  ? 110 VAL B CB  1 
ATOM 4151 C CG1 . VAL D 4 110 ? 324.812 342.258 448.275 1.00 95.02  ? 110 VAL B CG1 1 
ATOM 4152 C CG2 . VAL D 4 110 ? 325.526 340.172 447.154 1.00 95.02  ? 110 VAL B CG2 1 
ATOM 4153 N N   . GLN D 4 111 ? 321.637 342.848 447.170 1.00 100.41 ? 111 GLN B N   1 
ATOM 4154 C CA  . GLN D 4 111 ? 320.920 344.091 446.937 1.00 100.41 ? 111 GLN B CA  1 
ATOM 4155 C C   . GLN D 4 111 ? 320.566 344.732 448.267 1.00 100.41 ? 111 GLN B C   1 
ATOM 4156 O O   . GLN D 4 111 ? 319.935 344.106 449.119 1.00 100.41 ? 111 GLN B O   1 
ATOM 4157 C CB  . GLN D 4 111 ? 319.659 343.868 446.096 1.00 100.41 ? 111 GLN B CB  1 
ATOM 4158 C CG  . GLN D 4 111 ? 318.888 342.609 446.424 1.00 100.41 ? 111 GLN B CG  1 
ATOM 4159 C CD  . GLN D 4 111 ? 317.831 342.288 445.389 1.00 100.41 ? 111 GLN B CD  1 
ATOM 4160 O OE1 . GLN D 4 111 ? 317.689 342.993 444.392 1.00 100.41 ? 111 GLN B OE1 1 
ATOM 4161 N NE2 . GLN D 4 111 ? 317.077 341.222 445.626 1.00 100.41 ? 111 GLN B NE2 1 
ATOM 4162 N N   . CYS D 4 112 ? 320.986 345.979 448.440 1.00 105.83 ? 112 CYS B N   1 
ATOM 4163 C CA  . CYS D 4 112 ? 320.649 346.766 449.615 1.00 105.83 ? 112 CYS B CA  1 
ATOM 4164 C C   . CYS D 4 112 ? 319.786 347.934 449.172 1.00 105.83 ? 112 CYS B C   1 
ATOM 4165 O O   . CYS D 4 112 ? 319.999 348.493 448.093 1.00 105.83 ? 112 CYS B O   1 
ATOM 4166 C CB  . CYS D 4 112 ? 321.908 347.239 450.348 1.00 105.83 ? 112 CYS B CB  1 
ATOM 4167 S SG  . CYS D 4 112 ? 322.755 348.685 449.686 1.00 105.83 ? 112 CYS B SG  1 
ATOM 4168 N N   . ASN D 4 113 ? 318.784 348.268 449.977 1.00 106.19 ? 113 ASN B N   1 
ATOM 4169 C CA  . ASN D 4 113 ? 317.801 349.283 449.612 1.00 106.19 ? 113 ASN B CA  1 
ATOM 4170 C C   . ASN D 4 113 ? 317.964 350.489 450.526 1.00 106.19 ? 113 ASN B C   1 
ATOM 4171 O O   . ASN D 4 113 ? 317.682 350.424 451.723 1.00 106.19 ? 113 ASN B O   1 
ATOM 4172 C CB  . ASN D 4 113 ? 316.387 348.716 449.670 1.00 106.19 ? 113 ASN B CB  1 
ATOM 4173 C CG  . ASN D 4 113 ? 316.165 347.824 450.861 1.00 106.19 ? 113 ASN B CG  1 
ATOM 4174 O OD1 . ASN D 4 113 ? 317.070 347.599 451.658 1.00 106.19 ? 113 ASN B OD1 1 
ATOM 4175 N ND2 . ASN D 4 113 ? 314.954 347.308 450.992 1.00 106.19 ? 113 ASN B ND2 1 
ATOM 4176 N N   . ALA D 4 114 ? 318.421 351.592 449.953 1.00 106.61 ? 114 ALA B N   1 
ATOM 4177 C CA  . ALA D 4 114 ? 318.500 352.859 450.653 1.00 106.61 ? 114 ALA B CA  1 
ATOM 4178 C C   . ALA D 4 114 ? 317.817 353.925 449.816 1.00 106.61 ? 114 ALA B C   1 
ATOM 4179 O O   . ALA D 4 114 ? 317.591 353.751 448.617 1.00 106.61 ? 114 ALA B O   1 
ATOM 4180 C CB  . ALA D 4 114 ? 319.947 353.264 450.934 1.00 106.61 ? 114 ALA B CB  1 
ATOM 4181 N N   . SER D 4 115 ? 317.498 355.040 450.458 1.00 106.78 ? 115 SER B N   1 
ATOM 4182 C CA  . SER D 4 115 ? 316.813 356.133 449.787 1.00 106.78 ? 115 SER B CA  1 
ATOM 4183 C C   . SER D 4 115 ? 317.830 356.992 449.040 1.00 106.78 ? 115 SER B C   1 
ATOM 4184 O O   . SER D 4 115 ? 319.004 356.640 448.904 1.00 106.78 ? 115 SER B O   1 
ATOM 4185 C CB  . SER D 4 115 ? 316.014 356.946 450.795 1.00 106.78 ? 115 SER B CB  1 
ATOM 4186 O OG  . SER D 4 115 ? 316.766 357.139 451.977 1.00 106.78 ? 115 SER B OG  1 
ATOM 4187 N N   . LYS D 4 116 ? 317.386 358.140 448.544 1.00 106.55 ? 116 LYS B N   1 
ATOM 4188 C CA  . LYS D 4 116 ? 318.283 359.067 447.875 1.00 106.55 ? 116 LYS B CA  1 
ATOM 4189 C C   . LYS D 4 116 ? 319.006 359.985 448.846 1.00 106.55 ? 116 LYS B C   1 
ATOM 4190 O O   . LYS D 4 116 ? 319.822 360.801 448.412 1.00 106.55 ? 116 LYS B O   1 
ATOM 4191 C CB  . LYS D 4 116 ? 317.508 359.901 446.858 1.00 106.55 ? 116 LYS B CB  1 
ATOM 4192 C CG  . LYS D 4 116 ? 317.546 359.339 445.456 1.00 106.55 ? 116 LYS B CG  1 
ATOM 4193 C CD  . LYS D 4 116 ? 316.802 360.240 444.491 1.00 106.55 ? 116 LYS B CD  1 
ATOM 4194 C CE  . LYS D 4 116 ? 316.378 359.488 443.242 1.00 106.55 ? 116 LYS B CE  1 
ATOM 4195 N NZ  . LYS D 4 116 ? 315.167 360.088 442.619 1.00 106.55 ? 116 LYS B NZ  1 
ATOM 4196 N N   . PHE D 4 117 ? 318.730 359.873 450.140 1.00 102.37 ? 117 PHE B N   1 
ATOM 4197 C CA  . PHE D 4 117 ? 319.339 360.729 451.141 1.00 102.37 ? 117 PHE B CA  1 
ATOM 4198 C C   . PHE D 4 117 ? 320.470 360.045 451.892 1.00 102.37 ? 117 PHE B C   1 
ATOM 4199 O O   . PHE D 4 117 ? 321.057 360.660 452.784 1.00 102.37 ? 117 PHE B O   1 
ATOM 4200 C CB  . PHE D 4 117 ? 318.281 361.208 452.142 1.00 102.37 ? 117 PHE B CB  1 
ATOM 4201 C CG  . PHE D 4 117 ? 317.385 362.296 451.613 1.00 102.37 ? 117 PHE B CG  1 
ATOM 4202 C CD1 . PHE D 4 117 ? 316.419 362.026 450.657 1.00 102.37 ? 117 PHE B CD1 1 
ATOM 4203 C CD2 . PHE D 4 117 ? 317.496 363.585 452.088 1.00 102.37 ? 117 PHE B CD2 1 
ATOM 4204 C CE1 . PHE D 4 117 ? 315.601 363.022 450.177 1.00 102.37 ? 117 PHE B CE1 1 
ATOM 4205 C CE2 . PHE D 4 117 ? 316.678 364.584 451.611 1.00 102.37 ? 117 PHE B CE2 1 
ATOM 4206 C CZ  . PHE D 4 117 ? 315.730 364.299 450.655 1.00 102.37 ? 117 PHE B CZ  1 
ATOM 4207 N N   . HIS D 4 118 ? 320.775 358.795 451.564 1.00 100.38 ? 118 HIS B N   1 
ATOM 4208 C CA  . HIS D 4 118 ? 321.867 358.051 452.170 1.00 100.38 ? 118 HIS B CA  1 
ATOM 4209 C C   . HIS D 4 118 ? 323.083 358.071 451.254 1.00 100.38 ? 118 HIS B C   1 
ATOM 4210 O O   . HIS D 4 118 ? 323.010 358.473 450.094 1.00 100.38 ? 118 HIS B O   1 
ATOM 4211 C CB  . HIS D 4 118 ? 321.444 356.608 452.453 1.00 100.38 ? 118 HIS B CB  1 
ATOM 4212 C CG  . HIS D 4 118 ? 320.477 356.465 453.586 1.00 100.38 ? 118 HIS B CG  1 
ATOM 4213 N ND1 . HIS D 4 118 ? 319.124 356.309 453.392 1.00 100.38 ? 118 HIS B ND1 1 
ATOM 4214 C CD2 . HIS D 4 118 ? 320.671 356.441 454.924 1.00 100.38 ? 118 HIS B CD2 1 
ATOM 4215 C CE1 . HIS D 4 118 ? 318.524 356.200 454.563 1.00 100.38 ? 118 HIS B CE1 1 
ATOM 4216 N NE2 . HIS D 4 118 ? 319.440 356.278 455.509 1.00 100.38 ? 118 HIS B NE2 1 
ATOM 4217 N N   . GLN D 4 119 ? 324.214 357.618 451.787 1.00 105.09 ? 119 GLN B N   1 
ATOM 4218 C CA  . GLN D 4 119 ? 325.454 357.606 451.027 1.00 105.09 ? 119 GLN B CA  1 
ATOM 4219 C C   . GLN D 4 119 ? 326.380 356.530 451.571 1.00 105.09 ? 119 GLN B C   1 
ATOM 4220 O O   . GLN D 4 119 ? 326.343 356.207 452.759 1.00 105.09 ? 119 GLN B O   1 
ATOM 4221 C CB  . GLN D 4 119 ? 326.147 358.965 451.080 1.00 105.09 ? 119 GLN B CB  1 
ATOM 4222 C CG  . GLN D 4 119 ? 326.042 359.645 452.420 1.00 105.09 ? 119 GLN B CG  1 
ATOM 4223 C CD  . GLN D 4 119 ? 326.706 360.997 452.427 1.00 105.09 ? 119 GLN B CD  1 
ATOM 4224 O OE1 . GLN D 4 119 ? 327.903 361.108 452.673 1.00 105.09 ? 119 GLN B OE1 1 
ATOM 4225 N NE2 . GLN D 4 119 ? 325.932 362.037 452.153 1.00 105.09 ? 119 GLN B NE2 1 
ATOM 4226 N N   . GLY D 4 120 ? 327.209 355.982 450.693 1.00 102.01 ? 120 GLY B N   1 
ATOM 4227 C CA  . GLY D 4 120 ? 328.167 354.973 451.096 1.00 102.01 ? 120 GLY B CA  1 
ATOM 4228 C C   . GLY D 4 120 ? 328.650 354.198 449.892 1.00 102.01 ? 120 GLY B C   1 
ATOM 4229 O O   . GLY D 4 120 ? 328.233 354.446 448.760 1.00 102.01 ? 120 GLY B O   1 
ATOM 4230 N N   . CYS D 4 121 ? 329.540 353.243 450.159 1.00 101.73 ? 121 CYS B N   1 
ATOM 4231 C CA  . CYS D 4 121 ? 330.082 352.406 449.094 1.00 101.73 ? 121 CYS B CA  1 
ATOM 4232 C C   . CYS D 4 121 ? 330.506 351.057 449.652 1.00 101.73 ? 121 CYS B C   1 
ATOM 4233 O O   . CYS D 4 121 ? 331.287 350.998 450.604 1.00 101.73 ? 121 CYS B O   1 
ATOM 4234 C CB  . CYS D 4 121 ? 331.270 353.078 448.413 1.00 101.73 ? 121 CYS B CB  1 
ATOM 4235 S SG  . CYS D 4 121 ? 331.616 352.437 446.766 1.00 101.73 ? 121 CYS B SG  1 
ATOM 4236 N N   . LEU D 4 122 ? 330.015 349.985 449.038 1.00 97.50  ? 122 LEU B N   1 
ATOM 4237 C CA  . LEU D 4 122 ? 330.345 348.626 449.430 1.00 97.50  ? 122 LEU B CA  1 
ATOM 4238 C C   . LEU D 4 122 ? 331.232 347.979 448.379 1.00 97.50  ? 122 LEU B C   1 
ATOM 4239 O O   . LEU D 4 122 ? 331.224 348.368 447.210 1.00 97.50  ? 122 LEU B O   1 
ATOM 4240 C CB  . LEU D 4 122 ? 329.094 347.769 449.602 1.00 97.50  ? 122 LEU B CB  1 
ATOM 4241 C CG  . LEU D 4 122 ? 328.151 348.037 450.767 1.00 97.50  ? 122 LEU B CG  1 
ATOM 4242 C CD1 . LEU D 4 122 ? 327.094 346.959 450.806 1.00 97.50  ? 122 LEU B CD1 1 
ATOM 4243 C CD2 . LEU D 4 122 ? 328.907 348.080 452.066 1.00 97.50  ? 122 LEU B CD2 1 
ATOM 4244 N N   . LEU D 4 123 ? 331.992 346.979 448.808 1.00 94.36  ? 123 LEU B N   1 
ATOM 4245 C CA  . LEU D 4 123 ? 332.789 346.150 447.915 1.00 94.36  ? 123 LEU B CA  1 
ATOM 4246 C C   . LEU D 4 123 ? 332.372 344.705 448.124 1.00 94.36  ? 123 LEU B C   1 
ATOM 4247 O O   . LEU D 4 123 ? 332.469 344.190 449.240 1.00 94.36  ? 123 LEU B O   1 
ATOM 4248 C CB  . LEU D 4 123 ? 334.279 346.329 448.187 1.00 94.36  ? 123 LEU B CB  1 
ATOM 4249 C CG  . LEU D 4 123 ? 335.200 345.371 447.445 1.00 94.36  ? 123 LEU B CG  1 
ATOM 4250 C CD1 . LEU D 4 123 ? 335.119 345.583 445.954 1.00 94.36  ? 123 LEU B CD1 1 
ATOM 4251 C CD2 . LEU D 4 123 ? 336.623 345.512 447.922 1.00 94.36  ? 123 LEU B CD2 1 
ATOM 4252 N N   . VAL D 4 124 ? 331.910 344.057 447.060 1.00 90.54  ? 124 VAL B N   1 
ATOM 4253 C CA  . VAL D 4 124 ? 331.342 342.715 447.133 1.00 90.54  ? 124 VAL B CA  1 
ATOM 4254 C C   . VAL D 4 124 ? 332.276 341.785 446.375 1.00 90.54  ? 124 VAL B C   1 
ATOM 4255 O O   . VAL D 4 124 ? 332.315 341.814 445.143 1.00 90.54  ? 124 VAL B O   1 
ATOM 4256 C CB  . VAL D 4 124 ? 329.926 342.659 446.558 1.00 90.54  ? 124 VAL B CB  1 
ATOM 4257 C CG1 . VAL D 4 124 ? 329.366 341.267 446.694 1.00 90.54  ? 124 VAL B CG1 1 
ATOM 4258 C CG2 . VAL D 4 124 ? 329.037 343.655 447.256 1.00 90.54  ? 124 VAL B CG2 1 
ATOM 4259 N N   . VAL D 4 125 ? 333.018 340.947 447.095 1.00 89.82  ? 125 VAL B N   1 
ATOM 4260 C CA  . VAL D 4 125 ? 334.007 340.062 446.496 1.00 89.82  ? 125 VAL B CA  1 
ATOM 4261 C C   . VAL D 4 125 ? 333.550 338.622 446.729 1.00 89.82  ? 125 VAL B C   1 
ATOM 4262 O O   . VAL D 4 125 ? 332.843 338.323 447.689 1.00 89.82  ? 125 VAL B O   1 
ATOM 4263 C CB  . VAL D 4 125 ? 335.416 340.301 447.084 1.00 89.82  ? 125 VAL B CB  1 
ATOM 4264 C CG1 . VAL D 4 125 ? 336.506 339.686 446.239 1.00 89.82  ? 125 VAL B CG1 1 
ATOM 4265 C CG2 . VAL D 4 125 ? 335.678 341.749 447.258 1.00 89.82  ? 125 VAL B CG2 1 
ATOM 4266 N N   . CYS D 4 126 ? 333.955 337.722 445.833 1.00 101.75 ? 126 CYS B N   1 
ATOM 4267 C CA  . CYS D 4 126 ? 333.766 336.288 446.037 1.00 101.75 ? 126 CYS B CA  1 
ATOM 4268 C C   . CYS D 4 126 ? 335.130 335.619 445.884 1.00 101.75 ? 126 CYS B C   1 
ATOM 4269 O O   . CYS D 4 126 ? 335.551 335.301 444.770 1.00 101.75 ? 126 CYS B O   1 
ATOM 4270 C CB  . CYS D 4 126 ? 332.752 335.714 445.063 1.00 101.75 ? 126 CYS B CB  1 
ATOM 4271 S SG  . CYS D 4 126 ? 332.628 333.921 445.146 1.00 101.75 ? 126 CYS B SG  1 
ATOM 4272 N N   . VAL D 4 127 ? 335.806 335.400 447.007 1.00 101.80 ? 127 VAL B N   1 
ATOM 4273 C CA  . VAL D 4 127 ? 337.193 334.946 447.019 1.00 101.80 ? 127 VAL B CA  1 
ATOM 4274 C C   . VAL D 4 127 ? 337.201 333.422 446.971 1.00 101.80 ? 127 VAL B C   1 
ATOM 4275 O O   . VAL D 4 127 ? 336.524 332.789 447.793 1.00 101.80 ? 127 VAL B O   1 
ATOM 4276 C CB  . VAL D 4 127 ? 337.926 335.444 448.269 1.00 101.80 ? 127 VAL B CB  1 
ATOM 4277 C CG1 . VAL D 4 127 ? 339.351 334.972 448.257 1.00 101.80 ? 127 VAL B CG1 1 
ATOM 4278 C CG2 . VAL D 4 127 ? 337.868 336.943 448.361 1.00 101.80 ? 127 VAL B CG2 1 
ATOM 4279 N N   . PRO D 4 128 ? 337.945 332.801 446.058 1.00 100.88 ? 128 PRO B N   1 
ATOM 4280 C CA  . PRO D 4 128 ? 338.132 331.348 446.125 1.00 100.88 ? 128 PRO B CA  1 
ATOM 4281 C C   . PRO D 4 128 ? 339.330 330.990 446.996 1.00 100.88 ? 128 PRO B C   1 
ATOM 4282 O O   . PRO D 4 128 ? 340.402 331.586 446.869 1.00 100.88 ? 128 PRO B O   1 
ATOM 4283 C CB  . PRO D 4 128 ? 338.360 330.952 444.665 1.00 100.88 ? 128 PRO B CB  1 
ATOM 4284 C CG  . PRO D 4 128 ? 338.932 332.162 444.040 1.00 100.88 ? 128 PRO B CG  1 
ATOM 4285 C CD  . PRO D 4 128 ? 338.431 333.363 444.790 1.00 100.88 ? 128 PRO B CD  1 
ATOM 4286 N N   . GLU D 4 129 ? 339.125 330.014 447.889 1.00 109.44 ? 129 GLU B N   1 
ATOM 4287 C CA  . GLU D 4 129 ? 340.135 329.483 448.812 1.00 109.44 ? 129 GLU B CA  1 
ATOM 4288 C C   . GLU D 4 129 ? 340.722 330.580 449.699 1.00 109.44 ? 129 GLU B C   1 
ATOM 4289 O O   . GLU D 4 129 ? 341.901 330.920 449.621 1.00 109.44 ? 129 GLU B O   1 
ATOM 4290 C CB  . GLU D 4 129 ? 341.233 328.728 448.058 1.00 109.44 ? 129 GLU B CB  1 
ATOM 4291 C CG  . GLU D 4 129 ? 340.697 327.677 447.110 1.00 109.44 ? 129 GLU B CG  1 
ATOM 4292 C CD  . GLU D 4 129 ? 340.704 326.288 447.709 1.00 109.44 ? 129 GLU B CD  1 
ATOM 4293 O OE1 . GLU D 4 129 ? 341.407 326.083 448.716 1.00 109.44 ? 129 GLU B OE1 1 
ATOM 4294 O OE2 . GLU D 4 129 ? 340.008 325.402 447.177 1.00 109.44 ? 129 GLU B OE2 1 
ATOM 4295 N N   . ALA D 4 130 ? 339.862 331.144 450.542 1.00 110.33 ? 130 ALA B N   1 
ATOM 4296 C CA  . ALA D 4 130 ? 340.259 332.227 451.438 1.00 110.33 ? 130 ALA B CA  1 
ATOM 4297 C C   . ALA D 4 130 ? 340.703 331.631 452.769 1.00 110.33 ? 130 ALA B C   1 
ATOM 4298 O O   . ALA D 4 130 ? 339.950 331.551 453.739 1.00 110.33 ? 130 ALA B O   1 
ATOM 4299 C CB  . ALA D 4 130 ? 339.117 333.214 451.617 1.00 110.33 ? 130 ALA B CB  1 
ATOM 4300 N N   . GLU D 4 131 ? 341.960 331.211 452.808 1.00 116.63 ? 131 GLU B N   1 
ATOM 4301 C CA  . GLU D 4 131 ? 342.523 330.638 454.021 1.00 116.63 ? 131 GLU B CA  1 
ATOM 4302 C C   . GLU D 4 131 ? 342.855 331.744 455.010 1.00 116.63 ? 131 GLU B C   1 
ATOM 4303 O O   . GLU D 4 131 ? 343.694 332.602 454.729 1.00 116.63 ? 131 GLU B O   1 
ATOM 4304 C CB  . GLU D 4 131 ? 343.773 329.838 453.676 1.00 116.63 ? 131 GLU B CB  1 
ATOM 4305 C CG  . GLU D 4 131 ? 344.264 328.913 454.758 1.00 116.63 ? 131 GLU B CG  1 
ATOM 4306 C CD  . GLU D 4 131 ? 345.482 328.135 454.317 1.00 116.63 ? 131 GLU B CD  1 
ATOM 4307 O OE1 . GLU D 4 131 ? 346.182 327.578 455.185 1.00 116.63 ? 131 GLU B OE1 1 
ATOM 4308 O OE2 . GLU D 4 131 ? 345.743 328.079 453.099 1.00 116.63 ? 131 GLU B OE2 1 
ATOM 4309 N N   . MET D 4 132 ? 342.207 331.726 456.168 1.00 114.81 ? 132 MET B N   1 
ATOM 4310 C CA  . MET D 4 132 ? 342.349 332.790 457.149 1.00 114.81 ? 132 MET B CA  1 
ATOM 4311 C C   . MET D 4 132 ? 343.307 332.377 458.255 1.00 114.81 ? 132 MET B C   1 
ATOM 4312 O O   . MET D 4 132 ? 343.648 331.203 458.406 1.00 114.81 ? 132 MET B O   1 
ATOM 4313 C CB  . MET D 4 132 ? 340.992 333.169 457.743 1.00 114.81 ? 132 MET B CB  1 
ATOM 4314 C CG  . MET D 4 132 ? 340.009 333.649 456.703 1.00 114.81 ? 132 MET B CG  1 
ATOM 4315 S SD  . MET D 4 132 ? 338.493 334.293 457.407 1.00 114.81 ? 132 MET B SD  1 
ATOM 4316 C CE  . MET D 4 132 ? 337.667 334.833 455.921 1.00 114.81 ? 132 MET B CE  1 
ATOM 4317 N N   . GLY D 4 133 ? 343.748 333.362 459.028 1.00 118.33 ? 133 GLY B N   1 
ATOM 4318 C CA  . GLY D 4 133 ? 344.772 333.157 460.030 1.00 118.33 ? 133 GLY B CA  1 
ATOM 4319 C C   . GLY D 4 133 ? 344.285 333.442 461.437 1.00 118.33 ? 133 GLY B C   1 
ATOM 4320 O O   . GLY D 4 133 ? 343.481 334.339 461.661 1.00 118.33 ? 133 GLY B O   1 
ATOM 4321 N N   . CYS D 4 134 ? 344.797 332.669 462.387 1.00 125.15 ? 134 CYS B N   1 
ATOM 4322 C CA  . CYS D 4 134 ? 344.355 332.764 463.766 1.00 125.15 ? 134 CYS B CA  1 
ATOM 4323 C C   . CYS D 4 134 ? 345.015 333.949 464.461 1.00 125.15 ? 134 CYS B C   1 
ATOM 4324 O O   . CYS D 4 134 ? 346.074 334.432 464.057 1.00 125.15 ? 134 CYS B O   1 
ATOM 4325 C CB  . CYS D 4 134 ? 344.668 331.473 464.515 1.00 125.15 ? 134 CYS B CB  1 
ATOM 4326 S SG  . CYS D 4 134 ? 344.452 331.572 466.292 1.00 125.15 ? 134 CYS B SG  1 
ATOM 4327 N N   . SER D 4 135 ? 344.368 334.422 465.527 1.00 124.69 ? 135 SER B N   1 
ATOM 4328 C CA  . SER D 4 135 ? 344.941 335.503 466.318 1.00 124.69 ? 135 SER B CA  1 
ATOM 4329 C C   . SER D 4 135 ? 346.094 335.015 467.174 1.00 124.69 ? 135 SER B C   1 
ATOM 4330 O O   . SER D 4 135 ? 347.088 335.729 467.332 1.00 124.69 ? 135 SER B O   1 
ATOM 4331 C CB  . SER D 4 135 ? 343.878 336.128 467.212 1.00 124.69 ? 135 SER B CB  1 
ATOM 4332 O OG  . SER D 4 135 ? 343.816 335.445 468.447 1.00 124.69 ? 135 SER B OG  1 
ATOM 4333 N N   . ASN D 4 136 ? 345.977 333.819 467.732 1.00 127.69 ? 136 ASN B N   1 
ATOM 4334 C CA  . ASN D 4 136 ? 347.070 333.163 468.427 1.00 127.69 ? 136 ASN B CA  1 
ATOM 4335 C C   . ASN D 4 136 ? 348.072 332.674 467.393 1.00 127.69 ? 136 ASN B C   1 
ATOM 4336 O O   . ASN D 4 136 ? 347.701 332.002 466.429 1.00 127.69 ? 136 ASN B O   1 
ATOM 4337 C CB  . ASN D 4 136 ? 346.546 332.000 469.267 1.00 127.69 ? 136 ASN B CB  1 
ATOM 4338 C CG  . ASN D 4 136 ? 347.567 331.481 470.242 1.00 127.69 ? 136 ASN B CG  1 
ATOM 4339 O OD1 . ASN D 4 136 ? 348.623 332.079 470.428 1.00 127.69 ? 136 ASN B OD1 1 
ATOM 4340 N ND2 . ASN D 4 136 ? 347.255 330.364 470.884 1.00 127.69 ? 136 ASN B ND2 1 
ATOM 4341 N N   . LEU D 4 137 ? 349.343 333.017 467.591 1.00 123.51 ? 137 LEU B N   1 
ATOM 4342 C CA  . LEU D 4 137 ? 350.340 332.823 466.545 1.00 123.51 ? 137 LEU B CA  1 
ATOM 4343 C C   . LEU D 4 137 ? 350.798 331.381 466.386 1.00 123.51 ? 137 LEU B C   1 
ATOM 4344 O O   . LEU D 4 137 ? 351.580 331.103 465.473 1.00 123.51 ? 137 LEU B O   1 
ATOM 4345 C CB  . LEU D 4 137 ? 351.568 333.700 466.799 1.00 123.51 ? 137 LEU B CB  1 
ATOM 4346 C CG  . LEU D 4 137 ? 351.611 335.110 466.207 1.00 123.51 ? 137 LEU B CG  1 
ATOM 4347 C CD1 . LEU D 4 137 ? 351.521 335.028 464.698 1.00 123.51 ? 137 LEU B CD1 1 
ATOM 4348 C CD2 . LEU D 4 137 ? 350.540 336.029 466.767 1.00 123.51 ? 137 LEU B CD2 1 
ATOM 4349 N N   . ASN D 4 138 ? 350.349 330.460 467.233 1.00 125.24 ? 138 ASN B N   1 
ATOM 4350 C CA  . ASN D 4 138 ? 350.778 329.076 467.131 1.00 125.24 ? 138 ASN B CA  1 
ATOM 4351 C C   . ASN D 4 138 ? 349.693 328.131 466.646 1.00 125.24 ? 138 ASN B C   1 
ATOM 4352 O O   . ASN D 4 138 ? 350.022 327.071 466.106 1.00 125.24 ? 138 ASN B O   1 
ATOM 4353 C CB  . ASN D 4 138 ? 351.299 328.583 468.484 1.00 125.24 ? 138 ASN B CB  1 
ATOM 4354 C CG  . ASN D 4 138 ? 352.479 329.380 468.968 1.00 125.24 ? 138 ASN B CG  1 
ATOM 4355 O OD1 . ASN D 4 138 ? 353.557 329.332 468.378 1.00 125.24 ? 138 ASN B OD1 1 
ATOM 4356 N ND2 . ASN D 4 138 ? 352.286 330.125 470.048 1.00 125.24 ? 138 ASN B ND2 1 
ATOM 4357 N N   . ASN D 4 139 ? 348.426 328.475 466.814 1.00 126.32 ? 139 ASN B N   1 
ATOM 4358 C CA  . ASN D 4 139 ? 347.339 327.578 466.474 1.00 126.32 ? 139 ASN B CA  1 
ATOM 4359 C C   . ASN D 4 139 ? 346.682 328.010 465.170 1.00 126.32 ? 139 ASN B C   1 
ATOM 4360 O O   . ASN D 4 139 ? 347.074 328.995 464.540 1.00 126.32 ? 139 ASN B O   1 
ATOM 4361 C CB  . ASN D 4 139 ? 346.320 327.528 467.610 1.00 126.32 ? 139 ASN B CB  1 
ATOM 4362 C CG  . ASN D 4 139 ? 346.961 327.286 468.950 1.00 126.32 ? 139 ASN B CG  1 
ATOM 4363 O OD1 . ASN D 4 139 ? 348.108 326.855 469.031 1.00 126.32 ? 139 ASN B OD1 1 
ATOM 4364 N ND2 . ASN D 4 139 ? 346.222 327.557 470.017 1.00 126.32 ? 139 ASN B ND2 1 
ATOM 4365 N N   . THR D 4 140 ? 345.674 327.247 464.764 1.00 123.54 ? 140 THR B N   1 
ATOM 4366 C CA  . THR D 4 140 ? 344.789 327.518 463.651 1.00 123.54 ? 140 THR B CA  1 
ATOM 4367 C C   . THR D 4 140 ? 343.406 327.773 464.232 1.00 123.54 ? 140 THR B C   1 
ATOM 4368 O O   . THR D 4 140 ? 343.095 327.229 465.297 1.00 123.54 ? 140 THR B O   1 
ATOM 4369 C CB  . THR D 4 140 ? 344.763 326.325 462.688 1.00 123.54 ? 140 THR B CB  1 
ATOM 4370 O OG1 . THR D 4 140 ? 343.983 325.273 463.264 1.00 123.54 ? 140 THR B OG1 1 
ATOM 4371 C CG2 . THR D 4 140 ? 346.168 325.821 462.431 1.00 123.54 ? 140 THR B CG2 1 
ATOM 4372 N N   . PRO D 4 141 ? 342.569 328.602 463.599 1.00 123.57 ? 141 PRO B N   1 
ATOM 4373 C CA  . PRO D 4 141 ? 341.282 328.945 464.215 1.00 123.57 ? 141 PRO B CA  1 
ATOM 4374 C C   . PRO D 4 141 ? 340.326 327.768 464.231 1.00 123.57 ? 141 PRO B C   1 
ATOM 4375 O O   . PRO D 4 141 ? 340.307 326.939 463.320 1.00 123.57 ? 141 PRO B O   1 
ATOM 4376 C CB  . PRO D 4 141 ? 340.752 330.070 463.324 1.00 123.57 ? 141 PRO B CB  1 
ATOM 4377 C CG  . PRO D 4 141 ? 341.369 329.821 462.023 1.00 123.57 ? 141 PRO B CG  1 
ATOM 4378 C CD  . PRO D 4 141 ? 342.737 329.289 462.306 1.00 123.57 ? 141 PRO B CD  1 
ATOM 4379 N N   . GLU D 4 142 ? 339.529 327.695 465.292 1.00 130.51 ? 142 GLU B N   1 
ATOM 4380 C CA  . GLU D 4 142 ? 338.646 326.556 465.475 1.00 130.51 ? 142 GLU B CA  1 
ATOM 4381 C C   . GLU D 4 142 ? 337.452 326.656 464.530 1.00 130.51 ? 142 GLU B C   1 
ATOM 4382 O O   . GLU D 4 142 ? 337.293 327.625 463.785 1.00 130.51 ? 142 GLU B O   1 
ATOM 4383 C CB  . GLU D 4 142 ? 338.212 326.443 466.934 1.00 130.51 ? 142 GLU B CB  1 
ATOM 4384 C CG  . GLU D 4 142 ? 337.195 327.464 467.386 1.00 130.51 ? 142 GLU B CG  1 
ATOM 4385 C CD  . GLU D 4 142 ? 336.549 327.080 468.704 1.00 130.51 ? 142 GLU B CD  1 
ATOM 4386 O OE1 . GLU D 4 142 ? 336.432 325.867 468.975 1.00 130.51 ? 142 GLU B OE1 1 
ATOM 4387 O OE2 . GLU D 4 142 ? 336.159 327.987 469.471 1.00 130.51 ? 142 GLU B OE2 1 
ATOM 4388 N N   . PHE D 4 143 ? 336.600 325.631 464.564 1.00 126.14 ? 143 PHE B N   1 
ATOM 4389 C CA  . PHE D 4 143 ? 335.592 325.465 463.523 1.00 126.14 ? 143 PHE B CA  1 
ATOM 4390 C C   . PHE D 4 143 ? 334.478 326.493 463.646 1.00 126.14 ? 143 PHE B C   1 
ATOM 4391 O O   . PHE D 4 143 ? 333.974 326.990 462.633 1.00 126.14 ? 143 PHE B O   1 
ATOM 4392 C CB  . PHE D 4 143 ? 335.022 324.050 463.577 1.00 126.14 ? 143 PHE B CB  1 
ATOM 4393 C CG  . PHE D 4 143 ? 333.713 323.899 462.868 1.00 126.14 ? 143 PHE B CG  1 
ATOM 4394 C CD1 . PHE D 4 143 ? 333.647 323.980 461.488 1.00 126.14 ? 143 PHE B CD1 1 
ATOM 4395 C CD2 . PHE D 4 143 ? 332.547 323.678 463.581 1.00 126.14 ? 143 PHE B CD2 1 
ATOM 4396 C CE1 . PHE D 4 143 ? 332.440 323.845 460.830 1.00 126.14 ? 143 PHE B CE1 1 
ATOM 4397 C CE2 . PHE D 4 143 ? 331.335 323.543 462.931 1.00 126.14 ? 143 PHE B CE2 1 
ATOM 4398 C CZ  . PHE D 4 143 ? 331.283 323.626 461.553 1.00 126.14 ? 143 PHE B CZ  1 
ATOM 4399 N N   . SER D 4 144 ? 334.087 326.838 464.870 1.00 123.07 ? 144 SER B N   1 
ATOM 4400 C CA  . SER D 4 144 ? 332.958 327.737 465.053 1.00 123.07 ? 144 SER B CA  1 
ATOM 4401 C C   . SER D 4 144 ? 333.309 329.193 464.799 1.00 123.07 ? 144 SER B C   1 
ATOM 4402 O O   . SER D 4 144 ? 332.400 330.020 464.687 1.00 123.07 ? 144 SER B O   1 
ATOM 4403 C CB  . SER D 4 144 ? 332.390 327.595 466.462 1.00 123.07 ? 144 SER B CB  1 
ATOM 4404 O OG  . SER D 4 144 ? 331.153 328.272 466.566 1.00 123.07 ? 144 SER B OG  1 
ATOM 4405 N N   . GLU D 4 145 ? 334.590 329.526 464.701 1.00 123.71 ? 145 GLU B N   1 
ATOM 4406 C CA  . GLU D 4 145 ? 334.996 330.905 464.488 1.00 123.71 ? 145 GLU B CA  1 
ATOM 4407 C C   . GLU D 4 145 ? 335.223 331.242 463.025 1.00 123.71 ? 145 GLU B C   1 
ATOM 4408 O O   . GLU D 4 145 ? 335.348 332.422 462.692 1.00 123.71 ? 145 GLU B O   1 
ATOM 4409 C CB  . GLU D 4 145 ? 336.266 331.205 465.282 1.00 123.71 ? 145 GLU B CB  1 
ATOM 4410 C CG  . GLU D 4 145 ? 336.066 331.131 466.777 1.00 123.71 ? 145 GLU B CG  1 
ATOM 4411 C CD  . GLU D 4 145 ? 335.291 332.316 467.309 1.00 123.71 ? 145 GLU B CD  1 
ATOM 4412 O OE1 . GLU D 4 145 ? 335.421 333.418 466.736 1.00 123.71 ? 145 GLU B OE1 1 
ATOM 4413 O OE2 . GLU D 4 145 ? 334.543 332.148 468.294 1.00 123.71 ? 145 GLU B OE2 1 
ATOM 4414 N N   . LEU D 4 146 ? 335.273 330.246 462.147 1.00 113.98 ? 146 LEU B N   1 
ATOM 4415 C CA  . LEU D 4 146 ? 335.497 330.526 460.736 1.00 113.98 ? 146 LEU B CA  1 
ATOM 4416 C C   . LEU D 4 146 ? 334.189 330.711 459.986 1.00 113.98 ? 146 LEU B C   1 
ATOM 4417 O O   . LEU D 4 146 ? 334.072 331.613 459.152 1.00 113.98 ? 146 LEU B O   1 
ATOM 4418 C CB  . LEU D 4 146 ? 336.306 329.401 460.099 1.00 113.98 ? 146 LEU B CB  1 
ATOM 4419 C CG  . LEU D 4 146 ? 337.816 329.592 460.058 1.00 113.98 ? 146 LEU B CG  1 
ATOM 4420 C CD1 . LEU D 4 146 ? 338.484 328.255 459.891 1.00 113.98 ? 146 LEU B CD1 1 
ATOM 4421 C CD2 . LEU D 4 146 ? 338.190 330.514 458.925 1.00 113.98 ? 146 LEU B CD2 1 
ATOM 4422 N N   . SER D 4 147 ? 333.197 329.876 460.269 1.00 117.25 ? 147 SER B N   1 
ATOM 4423 C CA  . SER D 4 147 ? 331.985 329.866 459.472 1.00 117.25 ? 147 SER B CA  1 
ATOM 4424 C C   . SER D 4 147 ? 330.774 329.725 460.372 1.00 117.25 ? 147 SER B C   1 
ATOM 4425 O O   . SER D 4 147 ? 330.712 328.835 461.222 1.00 117.25 ? 147 SER B O   1 
ATOM 4426 C CB  . SER D 4 147 ? 331.988 328.720 458.464 1.00 117.25 ? 147 SER B CB  1 
ATOM 4427 O OG  . SER D 4 147 ? 331.590 327.511 459.084 1.00 117.25 ? 147 SER B OG  1 
ATOM 4428 N N   . GLY D 4 148 ? 329.806 330.604 460.163 1.00 120.45 ? 148 GLY B N   1 
ATOM 4429 C CA  . GLY D 4 148 ? 328.508 330.430 460.770 1.00 120.45 ? 148 GLY B CA  1 
ATOM 4430 C C   . GLY D 4 148 ? 327.543 329.891 459.741 1.00 120.45 ? 148 GLY B C   1 
ATOM 4431 O O   . GLY D 4 148 ? 327.482 330.404 458.620 1.00 120.45 ? 148 GLY B O   1 
ATOM 4432 N N   . GLY D 4 149 ? 326.814 328.838 460.093 1.00 127.29 ? 149 GLY B N   1 
ATOM 4433 C CA  . GLY D 4 149 ? 325.798 328.303 459.213 1.00 127.29 ? 149 GLY B CA  1 
ATOM 4434 C C   . GLY D 4 149 ? 324.664 329.290 459.063 1.00 127.29 ? 149 GLY B C   1 
ATOM 4435 O O   . GLY D 4 149 ? 323.966 329.577 460.038 1.00 127.29 ? 149 GLY B O   1 
ATOM 4436 N N   . ASP D 4 150 ? 324.502 329.811 457.839 1.00 124.00 ? 150 ASP B N   1 
ATOM 4437 C CA  . ASP D 4 150 ? 323.620 330.903 457.411 1.00 124.00 ? 150 ASP B CA  1 
ATOM 4438 C C   . ASP D 4 150 ? 323.541 332.068 458.396 1.00 124.00 ? 150 ASP B C   1 
ATOM 4439 O O   . ASP D 4 150 ? 322.472 332.644 458.611 1.00 124.00 ? 150 ASP B O   1 
ATOM 4440 C CB  . ASP D 4 150 ? 322.215 330.378 457.052 1.00 124.00 ? 150 ASP B CB  1 
ATOM 4441 C CG  . ASP D 4 150 ? 321.541 329.581 458.164 1.00 124.00 ? 150 ASP B CG  1 
ATOM 4442 O OD1 . ASP D 4 150 ? 321.294 330.125 459.260 1.00 124.00 ? 150 ASP B OD1 1 
ATOM 4443 O OD2 . ASP D 4 150 ? 321.193 328.409 457.911 1.00 124.00 ? 150 ASP B OD2 1 
ATOM 4444 N N   . SER D 4 151 ? 324.681 332.439 458.969 1.00 116.36 ? 151 SER B N   1 
ATOM 4445 C CA  . SER D 4 151 ? 324.784 333.588 459.855 1.00 116.36 ? 151 SER B CA  1 
ATOM 4446 C C   . SER D 4 151 ? 326.137 334.231 459.624 1.00 116.36 ? 151 SER B C   1 
ATOM 4447 O O   . SER D 4 151 ? 327.160 333.541 459.612 1.00 116.36 ? 151 SER B O   1 
ATOM 4448 C CB  . SER D 4 151 ? 324.624 333.187 461.322 1.00 116.36 ? 151 SER B CB  1 
ATOM 4449 O OG  . SER D 4 151 ? 323.257 333.121 461.676 1.00 116.36 ? 151 SER B OG  1 
ATOM 4450 N N   . ALA D 4 152 ? 326.141 335.542 459.434 1.00 104.16 ? 152 ALA B N   1 
ATOM 4451 C CA  . ALA D 4 152 ? 327.354 336.226 459.025 1.00 104.16 ? 152 ALA B CA  1 
ATOM 4452 C C   . ALA D 4 152 ? 328.277 336.447 460.207 1.00 104.16 ? 152 ALA B C   1 
ATOM 4453 O O   . ALA D 4 152 ? 327.859 336.961 461.246 1.00 104.16 ? 152 ALA B O   1 
ATOM 4454 C CB  . ALA D 4 152 ? 327.011 337.565 458.388 1.00 104.16 ? 152 ALA B CB  1 
ATOM 4455 N N   . ARG D 4 153 ? 329.534 336.059 460.048 1.00 105.31 ? 153 ARG B N   1 
ATOM 4456 C CA  . ARG D 4 153 ? 330.570 336.511 460.956 1.00 105.31 ? 153 ARG B CA  1 
ATOM 4457 C C   . ARG D 4 153 ? 331.002 337.906 460.536 1.00 105.31 ? 153 ARG B C   1 
ATOM 4458 O O   . ARG D 4 153 ? 330.868 338.282 459.371 1.00 105.31 ? 153 ARG B O   1 
ATOM 4459 C CB  . ARG D 4 153 ? 331.752 335.551 460.941 1.00 105.31 ? 153 ARG B CB  1 
ATOM 4460 C CG  . ARG D 4 153 ? 331.427 334.195 461.508 1.00 105.31 ? 153 ARG B CG  1 
ATOM 4461 C CD  . ARG D 4 153 ? 331.113 334.282 462.982 1.00 105.31 ? 153 ARG B CD  1 
ATOM 4462 N NE  . ARG D 4 153 ? 330.918 332.960 463.557 1.00 105.31 ? 153 ARG B NE  1 
ATOM 4463 C CZ  . ARG D 4 153 ? 329.731 332.409 463.769 1.00 105.31 ? 153 ARG B CZ  1 
ATOM 4464 N NH1 . ARG D 4 153 ? 329.644 331.197 464.291 1.00 105.31 ? 153 ARG B NH1 1 
ATOM 4465 N NH2 . ARG D 4 153 ? 328.630 333.074 463.465 1.00 105.31 ? 153 ARG B NH2 1 
ATOM 4466 N N   . MET D 4 154 ? 331.512 338.678 461.484 1.00 103.51 ? 154 MET B N   1 
ATOM 4467 C CA  . MET D 4 154 ? 331.720 340.099 461.269 1.00 103.51 ? 154 MET B CA  1 
ATOM 4468 C C   . MET D 4 154 ? 333.184 340.470 461.425 1.00 103.51 ? 154 MET B C   1 
ATOM 4469 O O   . MET D 4 154 ? 333.925 339.845 462.185 1.00 103.51 ? 154 MET B O   1 
ATOM 4470 C CB  . MET D 4 154 ? 330.874 340.918 462.236 1.00 103.51 ? 154 MET B CB  1 
ATOM 4471 C CG  . MET D 4 154 ? 329.396 340.740 462.004 1.00 103.51 ? 154 MET B CG  1 
ATOM 4472 S SD  . MET D 4 154 ? 328.357 341.762 463.044 1.00 103.51 ? 154 MET B SD  1 
ATOM 4473 C CE  . MET D 4 154 ? 326.750 341.336 462.384 1.00 103.51 ? 154 MET B CE  1 
ATOM 4474 N N   . PHE D 4 155 ? 333.590 341.497 460.692 1.00 99.59  ? 155 PHE B N   1 
ATOM 4475 C CA  . PHE D 4 155 ? 334.929 342.047 460.816 1.00 99.59  ? 155 PHE B CA  1 
ATOM 4476 C C   . PHE D 4 155 ? 334.968 343.018 461.991 1.00 99.59  ? 155 PHE B C   1 
ATOM 4477 O O   . PHE D 4 155 ? 333.937 343.398 462.548 1.00 99.59  ? 155 PHE B O   1 
ATOM 4478 C CB  . PHE D 4 155 ? 335.343 342.736 459.522 1.00 99.59  ? 155 PHE B CB  1 
ATOM 4479 C CG  . PHE D 4 155 ? 335.727 341.799 458.416 1.00 99.59  ? 155 PHE B CG  1 
ATOM 4480 C CD1 . PHE D 4 155 ? 336.831 340.986 458.534 1.00 99.59  ? 155 PHE B CD1 1 
ATOM 4481 C CD2 . PHE D 4 155 ? 334.997 341.758 457.242 1.00 99.59  ? 155 PHE B CD2 1 
ATOM 4482 C CE1 . PHE D 4 155 ? 337.192 340.140 457.515 1.00 99.59  ? 155 PHE B CE1 1 
ATOM 4483 C CE2 . PHE D 4 155 ? 335.356 340.911 456.223 1.00 99.59  ? 155 PHE B CE2 1 
ATOM 4484 C CZ  . PHE D 4 155 ? 336.452 340.103 456.362 1.00 99.59  ? 155 PHE B CZ  1 
ATOM 4485 N N   . THR D 4 156 ? 336.173 343.423 462.387 1.00 112.27 ? 156 THR B N   1 
ATOM 4486 C CA  . THR D 4 156 ? 336.377 344.488 463.359 1.00 112.27 ? 156 THR B CA  1 
ATOM 4487 C C   . THR D 4 156 ? 337.339 345.490 462.746 1.00 112.27 ? 156 THR B C   1 
ATOM 4488 O O   . THR D 4 156 ? 338.020 345.187 461.766 1.00 112.27 ? 156 THR B O   1 
ATOM 4489 C CB  . THR D 4 156 ? 336.968 343.999 464.692 1.00 112.27 ? 156 THR B CB  1 
ATOM 4490 O OG1 . THR D 4 156 ? 338.390 343.903 464.568 1.00 112.27 ? 156 THR B OG1 1 
ATOM 4491 C CG2 . THR D 4 156 ? 336.431 342.643 465.094 1.00 112.27 ? 156 THR B CG2 1 
ATOM 4492 N N   . ASP D 4 157 ? 337.405 346.680 463.331 1.00 122.63 ? 157 ASP B N   1 
ATOM 4493 C CA  . ASP D 4 157 ? 338.373 347.673 462.889 1.00 122.63 ? 157 ASP B CA  1 
ATOM 4494 C C   . ASP D 4 157 ? 339.557 347.814 463.836 1.00 122.63 ? 157 ASP B C   1 
ATOM 4495 O O   . ASP D 4 157 ? 340.295 348.797 463.735 1.00 122.63 ? 157 ASP B O   1 
ATOM 4496 C CB  . ASP D 4 157 ? 337.700 349.033 462.702 1.00 122.63 ? 157 ASP B CB  1 
ATOM 4497 C CG  . ASP D 4 157 ? 336.715 349.350 463.799 1.00 122.63 ? 157 ASP B CG  1 
ATOM 4498 O OD1 . ASP D 4 157 ? 336.763 348.687 464.854 1.00 122.63 ? 157 ASP B OD1 1 
ATOM 4499 O OD2 . ASP D 4 157 ? 335.878 350.257 463.604 1.00 122.63 ? 157 ASP B OD2 1 
ATOM 4500 N N   . THR D 4 158 ? 339.738 346.884 464.766 1.00 119.82 ? 158 THR B N   1 
ATOM 4501 C CA  . THR D 4 158 ? 340.871 346.852 465.682 1.00 119.82 ? 158 THR B CA  1 
ATOM 4502 C C   . THR D 4 158 ? 341.569 345.500 465.571 1.00 119.82 ? 158 THR B C   1 
ATOM 4503 O O   . THR D 4 158 ? 341.282 344.699 464.681 1.00 119.82 ? 158 THR B O   1 
ATOM 4504 C CB  . THR D 4 158 ? 340.430 347.095 467.128 1.00 119.82 ? 158 THR B CB  1 
ATOM 4505 O OG1 . THR D 4 158 ? 339.711 345.953 467.603 1.00 119.82 ? 158 THR B OG1 1 
ATOM 4506 C CG2 . THR D 4 158 ? 339.551 348.326 467.249 1.00 119.82 ? 158 THR B CG2 1 
ATOM 4507 N N   . GLN D 4 159 ? 342.504 345.250 466.481 1.00 117.11 ? 159 GLN B N   1 
ATOM 4508 C CA  . GLN D 4 159 ? 343.141 343.946 466.580 1.00 117.11 ? 159 GLN B CA  1 
ATOM 4509 C C   . GLN D 4 159 ? 342.359 343.047 467.523 1.00 117.11 ? 159 GLN B C   1 
ATOM 4510 O O   . GLN D 4 159 ? 341.651 343.524 468.412 1.00 117.11 ? 159 GLN B O   1 
ATOM 4511 C CB  . GLN D 4 159 ? 344.575 344.063 467.086 1.00 117.11 ? 159 GLN B CB  1 
ATOM 4512 C CG  . GLN D 4 159 ? 345.551 344.662 466.115 1.00 117.11 ? 159 GLN B CG  1 
ATOM 4513 C CD  . GLN D 4 159 ? 346.975 344.272 466.442 1.00 117.11 ? 159 GLN B CD  1 
ATOM 4514 O OE1 . GLN D 4 159 ? 347.900 345.065 466.282 1.00 117.11 ? 159 GLN B OE1 1 
ATOM 4515 N NE2 . GLN D 4 159 ? 347.158 343.044 466.904 1.00 117.11 ? 159 GLN B NE2 1 
ATOM 4516 N N   . VAL D 4 160 ? 342.493 341.746 467.323 1.00 118.42 ? 160 VAL B N   1 
ATOM 4517 C CA  . VAL D 4 160 ? 341.976 340.769 468.271 1.00 118.42 ? 160 VAL B CA  1 
ATOM 4518 C C   . VAL D 4 160 ? 343.136 340.277 469.124 1.00 118.42 ? 160 VAL B C   1 
ATOM 4519 O O   . VAL D 4 160 ? 344.220 339.990 468.603 1.00 118.42 ? 160 VAL B O   1 
ATOM 4520 C CB  . VAL D 4 160 ? 341.272 339.623 467.529 1.00 118.42 ? 160 VAL B CB  1 
ATOM 4521 C CG1 . VAL D 4 160 ? 341.029 338.431 468.427 1.00 118.42 ? 160 VAL B CG1 1 
ATOM 4522 C CG2 . VAL D 4 160 ? 339.960 340.111 466.994 1.00 118.42 ? 160 VAL B CG2 1 
ATOM 4523 N N   . GLY D 4 161 ? 342.926 340.221 470.439 1.00 125.52 ? 161 GLY B N   1 
ATOM 4524 C CA  . GLY D 4 161 ? 343.998 339.869 471.347 1.00 125.52 ? 161 GLY B CA  1 
ATOM 4525 C C   . GLY D 4 161 ? 344.452 338.432 471.191 1.00 125.52 ? 161 GLY B C   1 
ATOM 4526 O O   . GLY D 4 161 ? 343.687 337.548 470.820 1.00 125.52 ? 161 GLY B O   1 
ATOM 4527 N N   . GLU D 4 162 ? 345.738 338.218 471.460 1.00 137.51 ? 162 GLU B N   1 
ATOM 4528 C CA  . GLU D 4 162 ? 346.423 336.966 471.168 1.00 137.51 ? 162 GLU B CA  1 
ATOM 4529 C C   . GLU D 4 162 ? 346.267 335.922 472.263 1.00 137.51 ? 162 GLU B C   1 
ATOM 4530 O O   . GLU D 4 162 ? 346.233 334.727 471.954 1.00 137.51 ? 162 GLU B O   1 
ATOM 4531 C CB  . GLU D 4 162 ? 347.906 337.276 470.899 1.00 137.51 ? 162 GLU B CB  1 
ATOM 4532 C CG  . GLU D 4 162 ? 348.830 336.114 470.515 1.00 137.51 ? 162 GLU B CG  1 
ATOM 4533 C CD  . GLU D 4 162 ? 349.458 335.413 471.708 1.00 137.51 ? 162 GLU B CD  1 
ATOM 4534 O OE1 . GLU D 4 162 ? 350.084 334.351 471.515 1.00 137.51 ? 162 GLU B OE1 1 
ATOM 4535 O OE2 . GLU D 4 162 ? 349.333 335.930 472.838 1.00 137.51 ? 162 GLU B OE2 1 
ATOM 4536 N N   . SER D 4 163 ? 346.150 336.330 473.527 1.00 140.22 ? 163 SER B N   1 
ATOM 4537 C CA  . SER D 4 163 ? 346.283 335.368 474.619 1.00 140.22 ? 163 SER B CA  1 
ATOM 4538 C C   . SER D 4 163 ? 344.985 334.618 474.902 1.00 140.22 ? 163 SER B C   1 
ATOM 4539 O O   . SER D 4 163 ? 344.914 333.858 475.874 1.00 140.22 ? 163 SER B O   1 
ATOM 4540 C CB  . SER D 4 163 ? 346.776 336.071 475.881 1.00 140.22 ? 163 SER B CB  1 
ATOM 4541 O OG  . SER D 4 163 ? 348.065 336.625 475.689 1.00 140.22 ? 163 SER B OG  1 
ATOM 4542 N N   . ASN D 4 164 ? 343.961 334.807 474.075 1.00 133.87 ? 164 ASN B N   1 
ATOM 4543 C CA  . ASN D 4 164 ? 342.705 334.086 474.223 1.00 133.87 ? 164 ASN B CA  1 
ATOM 4544 C C   . ASN D 4 164 ? 342.854 332.627 473.799 1.00 133.87 ? 164 ASN B C   1 
ATOM 4545 O O   . ASN D 4 164 ? 343.942 332.169 473.441 1.00 133.87 ? 164 ASN B O   1 
ATOM 4546 C CB  . ASN D 4 164 ? 341.638 334.753 473.378 1.00 133.87 ? 164 ASN B CB  1 
ATOM 4547 C CG  . ASN D 4 164 ? 342.052 334.846 471.943 1.00 133.87 ? 164 ASN B CG  1 
ATOM 4548 O OD1 . ASN D 4 164 ? 343.241 334.882 471.639 1.00 133.87 ? 164 ASN B OD1 1 
ATOM 4549 N ND2 . ASN D 4 164 ? 341.084 334.891 471.048 1.00 133.87 ? 164 ASN B ND2 1 
ATOM 4550 N N   . ALA D 4 165 ? 341.741 331.891 473.852 1.00 136.70 ? 165 ALA B N   1 
ATOM 4551 C CA  . ALA D 4 165 ? 341.750 330.478 473.482 1.00 136.70 ? 165 ALA B CA  1 
ATOM 4552 C C   . ALA D 4 165 ? 342.083 330.263 472.005 1.00 136.70 ? 165 ALA B C   1 
ATOM 4553 O O   . ALA D 4 165 ? 343.205 329.861 471.685 1.00 136.70 ? 165 ALA B O   1 
ATOM 4554 C CB  . ALA D 4 165 ? 340.400 329.841 473.825 1.00 136.70 ? 165 ALA B CB  1 
ATOM 4555 N N   . LYS D 4 166 ? 341.161 330.619 471.099 1.00 131.25 ? 166 LYS B N   1 
ATOM 4556 C CA  . LYS D 4 166 ? 341.309 330.440 469.643 1.00 131.25 ? 166 LYS B CA  1 
ATOM 4557 C C   . LYS D 4 166 ? 340.271 331.304 468.929 1.00 131.25 ? 166 LYS B C   1 
ATOM 4558 O O   . LYS D 4 166 ? 339.073 331.033 469.031 1.00 131.25 ? 166 LYS B O   1 
ATOM 4559 C CB  . LYS D 4 166 ? 341.167 328.965 469.236 1.00 131.25 ? 166 LYS B CB  1 
ATOM 4560 C CG  . LYS D 4 166 ? 342.477 328.201 469.085 1.00 131.25 ? 166 LYS B CG  1 
ATOM 4561 C CD  . LYS D 4 166 ? 342.306 326.713 469.323 1.00 131.25 ? 166 LYS B CD  1 
ATOM 4562 C CE  . LYS D 4 166 ? 341.733 326.010 468.111 1.00 131.25 ? 166 LYS B CE  1 
ATOM 4563 N NZ  . LYS D 4 166 ? 341.787 324.529 468.257 1.00 131.25 ? 166 LYS B NZ  1 
ATOM 4564 N N   . LYS D 4 167 ? 340.728 332.324 468.199 1.00 124.47 ? 167 LYS B N   1 
ATOM 4565 C CA  . LYS D 4 167 ? 339.852 333.185 467.413 1.00 124.47 ? 167 LYS B CA  1 
ATOM 4566 C C   . LYS D 4 167 ? 340.556 333.608 466.134 1.00 124.47 ? 167 LYS B C   1 
ATOM 4567 O O   . LYS D 4 167 ? 341.768 333.445 465.991 1.00 124.47 ? 167 LYS B O   1 
ATOM 4568 C CB  . LYS D 4 167 ? 339.420 334.447 468.173 1.00 124.47 ? 167 LYS B CB  1 
ATOM 4569 C CG  . LYS D 4 167 ? 338.328 334.234 469.204 1.00 124.47 ? 167 LYS B CG  1 
ATOM 4570 C CD  . LYS D 4 167 ? 337.977 335.520 469.923 1.00 124.47 ? 167 LYS B CD  1 
ATOM 4571 C CE  . LYS D 4 167 ? 337.238 336.473 469.011 1.00 124.47 ? 167 LYS B CE  1 
ATOM 4572 N NZ  . LYS D 4 167 ? 336.735 337.655 469.759 1.00 124.47 ? 167 LYS B NZ  1 
ATOM 4573 N N   . VAL D 4 168 ? 339.781 334.168 465.213 1.00 115.68 ? 168 VAL B N   1 
ATOM 4574 C CA  . VAL D 4 168 ? 340.305 334.613 463.926 1.00 115.68 ? 168 VAL B CA  1 
ATOM 4575 C C   . VAL D 4 168 ? 340.816 336.038 464.057 1.00 115.68 ? 168 VAL B C   1 
ATOM 4576 O O   . VAL D 4 168 ? 340.143 336.899 464.631 1.00 115.68 ? 168 VAL B O   1 
ATOM 4577 C CB  . VAL D 4 168 ? 339.221 334.518 462.844 1.00 115.68 ? 168 VAL B CB  1 
ATOM 4578 C CG1 . VAL D 4 168 ? 339.799 334.800 461.478 1.00 115.68 ? 168 VAL B CG1 1 
ATOM 4579 C CG2 . VAL D 4 168 ? 338.590 333.155 462.870 1.00 115.68 ? 168 VAL B CG2 1 
ATOM 4580 N N   . GLN D 4 169 ? 342.008 336.292 463.523 1.00 114.08 ? 169 GLN B N   1 
ATOM 4581 C CA  . GLN D 4 169 ? 342.531 337.652 463.446 1.00 114.08 ? 169 GLN B CA  1 
ATOM 4582 C C   . GLN D 4 169 ? 341.746 338.416 462.395 1.00 114.08 ? 169 GLN B C   1 
ATOM 4583 O O   . GLN D 4 169 ? 341.942 338.210 461.195 1.00 114.08 ? 169 GLN B O   1 
ATOM 4584 C CB  . GLN D 4 169 ? 344.014 337.638 463.104 1.00 114.08 ? 169 GLN B CB  1 
ATOM 4585 C CG  . GLN D 4 169 ? 344.605 339.015 462.991 1.00 114.08 ? 169 GLN B CG  1 
ATOM 4586 C CD  . GLN D 4 169 ? 344.672 339.712 464.321 1.00 114.08 ? 169 GLN B CD  1 
ATOM 4587 O OE1 . GLN D 4 169 ? 343.794 340.495 464.669 1.00 114.08 ? 169 GLN B OE1 1 
ATOM 4588 N NE2 . GLN D 4 169 ? 345.719 339.430 465.080 1.00 114.08 ? 169 GLN B NE2 1 
ATOM 4589 N N   . THR D 4 170 ? 340.855 339.295 462.833 1.00 109.99 ? 170 THR B N   1 
ATOM 4590 C CA  . THR D 4 170 ? 339.904 339.876 461.900 1.00 109.99 ? 170 THR B CA  1 
ATOM 4591 C C   . THR D 4 170 ? 339.986 341.395 461.822 1.00 109.99 ? 170 THR B C   1 
ATOM 4592 O O   . THR D 4 170 ? 338.958 342.079 461.813 1.00 109.99 ? 170 THR B O   1 
ATOM 4593 C CB  . THR D 4 170 ? 338.493 339.427 462.265 1.00 109.99 ? 170 THR B CB  1 
ATOM 4594 O OG1 . THR D 4 170 ? 337.545 340.199 461.529 1.00 109.99 ? 170 THR B OG1 1 
ATOM 4595 C CG2 . THR D 4 170 ? 338.237 339.569 463.750 1.00 109.99 ? 170 THR B CG2 1 
ATOM 4596 N N   . ALA D 4 171 ? 341.199 341.933 461.746 1.00 109.68 ? 171 ALA B N   1 
ATOM 4597 C CA  . ALA D 4 171 ? 341.365 343.338 461.404 1.00 109.68 ? 171 ALA B CA  1 
ATOM 4598 C C   . ALA D 4 171 ? 340.986 343.543 459.946 1.00 109.68 ? 171 ALA B C   1 
ATOM 4599 O O   . ALA D 4 171 ? 341.466 342.821 459.069 1.00 109.68 ? 171 ALA B O   1 
ATOM 4600 C CB  . ALA D 4 171 ? 342.801 343.783 461.652 1.00 109.68 ? 171 ALA B CB  1 
ATOM 4601 N N   . VAL D 4 172 ? 340.124 344.528 459.687 1.00 103.65 ? 172 VAL B N   1 
ATOM 4602 C CA  . VAL D 4 172 ? 339.482 344.624 458.380 1.00 103.65 ? 172 VAL B CA  1 
ATOM 4603 C C   . VAL D 4 172 ? 340.461 345.125 457.324 1.00 103.65 ? 172 VAL B C   1 
ATOM 4604 O O   . VAL D 4 172 ? 340.374 344.741 456.153 1.00 103.65 ? 172 VAL B O   1 
ATOM 4605 C CB  . VAL D 4 172 ? 338.217 345.502 458.477 1.00 103.65 ? 172 VAL B CB  1 
ATOM 4606 C CG1 . VAL D 4 172 ? 338.545 346.919 458.913 1.00 103.65 ? 172 VAL B CG1 1 
ATOM 4607 C CG2 . VAL D 4 172 ? 337.423 345.494 457.184 1.00 103.65 ? 172 VAL B CG2 1 
ATOM 4608 N N   . TRP D 4 173 ? 341.455 345.922 457.721 1.00 106.89 ? 173 TRP B N   1 
ATOM 4609 C CA  . TRP D 4 173 ? 342.360 346.483 456.727 1.00 106.89 ? 173 TRP B CA  1 
ATOM 4610 C C   . TRP D 4 173 ? 343.381 345.477 456.223 1.00 106.89 ? 173 TRP B C   1 
ATOM 4611 O O   . TRP D 4 173 ? 344.080 345.772 455.251 1.00 106.89 ? 173 TRP B O   1 
ATOM 4612 C CB  . TRP D 4 173 ? 343.075 347.709 457.285 1.00 106.89 ? 173 TRP B CB  1 
ATOM 4613 C CG  . TRP D 4 173 ? 344.001 347.424 458.403 1.00 106.89 ? 173 TRP B CG  1 
ATOM 4614 C CD1 . TRP D 4 173 ? 345.328 347.150 458.315 1.00 106.89 ? 173 TRP B CD1 1 
ATOM 4615 C CD2 . TRP D 4 173 ? 343.679 347.409 459.792 1.00 106.89 ? 173 TRP B CD2 1 
ATOM 4616 N NE1 . TRP D 4 173 ? 345.854 346.953 459.563 1.00 106.89 ? 173 TRP B NE1 1 
ATOM 4617 C CE2 . TRP D 4 173 ? 344.859 347.106 460.488 1.00 106.89 ? 173 TRP B CE2 1 
ATOM 4618 C CE3 . TRP D 4 173 ? 342.506 347.616 460.514 1.00 106.89 ? 173 TRP B CE3 1 
ATOM 4619 C CZ2 . TRP D 4 173 ? 344.900 347.006 461.867 1.00 106.89 ? 173 TRP B CZ2 1 
ATOM 4620 C CZ3 . TRP D 4 173 ? 342.548 347.515 461.880 1.00 106.89 ? 173 TRP B CZ3 1 
ATOM 4621 C CH2 . TRP D 4 173 ? 343.736 347.213 462.545 1.00 106.89 ? 173 TRP B CH2 1 
ATOM 4622 N N   . ASN D 4 174 ? 343.490 344.311 456.856 1.00 102.89 ? 174 ASN B N   1 
ATOM 4623 C CA  . ASN D 4 174 ? 344.271 343.213 456.317 1.00 102.89 ? 174 ASN B CA  1 
ATOM 4624 C C   . ASN D 4 174 ? 343.416 342.044 455.863 1.00 102.89 ? 174 ASN B C   1 
ATOM 4625 O O   . ASN D 4 174 ? 343.974 341.014 455.472 1.00 102.89 ? 174 ASN B O   1 
ATOM 4626 C CB  . ASN D 4 174 ? 345.297 342.725 457.344 1.00 102.89 ? 174 ASN B CB  1 
ATOM 4627 C CG  . ASN D 4 174 ? 346.529 343.588 457.375 1.00 102.89 ? 174 ASN B CG  1 
ATOM 4628 O OD1 . ASN D 4 174 ? 347.349 343.487 458.280 1.00 102.89 ? 174 ASN B OD1 1 
ATOM 4629 N ND2 . ASN D 4 174 ? 346.662 344.455 456.387 1.00 102.89 ? 174 ASN B ND2 1 
ATOM 4630 N N   . ALA D 4 175 ? 342.088 342.165 455.965 1.00 100.80 ? 175 ALA B N   1 
ATOM 4631 C CA  . ALA D 4 175 ? 341.097 341.244 455.393 1.00 100.80 ? 175 ALA B CA  1 
ATOM 4632 C C   . ALA D 4 175 ? 341.150 339.841 455.995 1.00 100.80 ? 175 ALA B C   1 
ATOM 4633 O O   . ALA D 4 175 ? 340.535 338.914 455.469 1.00 100.80 ? 175 ALA B O   1 
ATOM 4634 C CB  . ALA D 4 175 ? 341.212 341.167 453.868 1.00 100.80 ? 175 ALA B CB  1 
ATOM 4635 N N   . GLY D 4 176 ? 341.865 339.656 457.103 1.00 104.56 ? 176 GLY B N   1 
ATOM 4636 C CA  . GLY D 4 176 ? 341.995 338.352 457.717 1.00 104.56 ? 176 GLY B CA  1 
ATOM 4637 C C   . GLY D 4 176 ? 342.898 337.373 457.000 1.00 104.56 ? 176 GLY B C   1 
ATOM 4638 O O   . GLY D 4 176 ? 343.093 336.262 457.500 1.00 104.56 ? 176 GLY B O   1 
ATOM 4639 N N   . MET D 4 177 ? 343.455 337.739 455.846 1.00 99.88  ? 177 MET B N   1 
ATOM 4640 C CA  . MET D 4 177 ? 344.310 336.855 455.068 1.00 99.88  ? 177 MET B CA  1 
ATOM 4641 C C   . MET D 4 177 ? 345.725 337.394 454.928 1.00 99.88  ? 177 MET B C   1 
ATOM 4642 O O   . MET D 4 177 ? 346.471 336.922 454.066 1.00 99.88  ? 177 MET B O   1 
ATOM 4643 C CB  . MET D 4 177 ? 343.708 336.614 453.681 1.00 99.88  ? 177 MET B CB  1 
ATOM 4644 C CG  . MET D 4 177 ? 342.197 336.490 453.672 1.00 99.88  ? 177 MET B CG  1 
ATOM 4645 S SD  . MET D 4 177 ? 341.521 335.992 452.084 1.00 99.88  ? 177 MET B SD  1 
ATOM 4646 C CE  . MET D 4 177 ? 342.511 336.978 450.976 1.00 99.88  ? 177 MET B CE  1 
ATOM 4647 N N   . GLY D 4 178 ? 346.110 338.372 455.742 1.00 100.80 ? 178 GLY B N   1 
ATOM 4648 C CA  . GLY D 4 178 ? 347.449 338.918 455.700 1.00 100.80 ? 178 GLY B CA  1 
ATOM 4649 C C   . GLY D 4 178 ? 347.771 339.733 454.473 1.00 100.80 ? 178 GLY B C   1 
ATOM 4650 O O   . GLY D 4 178 ? 348.951 339.896 454.151 1.00 100.80 ? 178 GLY B O   1 
ATOM 4651 N N   . VAL D 4 179 ? 346.767 340.259 453.787 1.00 101.20 ? 179 VAL B N   1 
ATOM 4652 C CA  . VAL D 4 179 ? 346.952 340.920 452.507 1.00 101.20 ? 179 VAL B CA  1 
ATOM 4653 C C   . VAL D 4 179 ? 346.287 342.292 452.580 1.00 101.20 ? 179 VAL B C   1 
ATOM 4654 O O   . VAL D 4 179 ? 345.322 342.496 453.318 1.00 101.20 ? 179 VAL B O   1 
ATOM 4655 C CB  . VAL D 4 179 ? 346.378 340.039 451.375 1.00 101.20 ? 179 VAL B CB  1 
ATOM 4656 C CG1 . VAL D 4 179 ? 344.886 339.820 451.546 1.00 101.20 ? 179 VAL B CG1 1 
ATOM 4657 C CG2 . VAL D 4 179 ? 346.700 340.571 450.023 1.00 101.20 ? 179 VAL B CG2 1 
ATOM 4658 N N   . GLY D 4 180 ? 346.851 343.256 451.855 1.00 98.65  ? 180 GLY B N   1 
ATOM 4659 C CA  . GLY D 4 180 ? 346.309 344.608 451.862 1.00 98.65  ? 180 GLY B CA  1 
ATOM 4660 C C   . GLY D 4 180 ? 344.924 344.654 451.244 1.00 98.65  ? 180 GLY B C   1 
ATOM 4661 O O   . GLY D 4 180 ? 344.706 344.155 450.135 1.00 98.65  ? 180 GLY B O   1 
ATOM 4662 N N   . VAL D 4 181 ? 343.979 345.267 451.962 1.00 94.84  ? 181 VAL B N   1 
ATOM 4663 C CA  . VAL D 4 181 ? 342.563 345.157 451.622 1.00 94.84  ? 181 VAL B CA  1 
ATOM 4664 C C   . VAL D 4 181 ? 342.201 345.960 450.378 1.00 94.84  ? 181 VAL B C   1 
ATOM 4665 O O   . VAL D 4 181 ? 341.139 345.737 449.788 1.00 94.84  ? 181 VAL B O   1 
ATOM 4666 C CB  . VAL D 4 181 ? 341.718 345.574 452.841 1.00 94.84  ? 181 VAL B CB  1 
ATOM 4667 C CG1 . VAL D 4 181 ? 341.690 347.072 452.999 1.00 94.84  ? 181 VAL B CG1 1 
ATOM 4668 C CG2 . VAL D 4 181 ? 340.315 344.995 452.786 1.00 94.84  ? 181 VAL B CG2 1 
ATOM 4669 N N   . GLY D 4 182 ? 343.064 346.875 449.940 1.00 96.83  ? 182 GLY B N   1 
ATOM 4670 C CA  . GLY D 4 182 ? 342.797 347.581 448.706 1.00 96.83  ? 182 GLY B CA  1 
ATOM 4671 C C   . GLY D 4 182 ? 342.945 346.723 447.472 1.00 96.83  ? 182 GLY B C   1 
ATOM 4672 O O   . GLY D 4 182 ? 342.271 346.978 446.472 1.00 96.83  ? 182 GLY B O   1 
ATOM 4673 N N   . ASN D 4 183 ? 343.788 345.699 447.528 1.00 91.54  ? 183 ASN B N   1 
ATOM 4674 C CA  . ASN D 4 183 ? 344.078 344.871 446.371 1.00 91.54  ? 183 ASN B CA  1 
ATOM 4675 C C   . ASN D 4 183 ? 343.113 343.710 446.211 1.00 91.54  ? 183 ASN B C   1 
ATOM 4676 O O   . ASN D 4 183 ? 343.395 342.797 445.434 1.00 91.54  ? 183 ASN B O   1 
ATOM 4677 C CB  . ASN D 4 183 ? 345.502 344.333 446.452 1.00 91.54  ? 183 ASN B CB  1 
ATOM 4678 C CG  . ASN D 4 183 ? 346.515 345.413 446.701 1.00 91.54  ? 183 ASN B CG  1 
ATOM 4679 O OD1 . ASN D 4 183 ? 346.399 346.517 446.179 1.00 91.54  ? 183 ASN B OD1 1 
ATOM 4680 N ND2 . ASN D 4 183 ? 347.524 345.103 447.501 1.00 91.54  ? 183 ASN B ND2 1 
ATOM 4681 N N   . LEU D 4 184 ? 341.978 343.722 446.900 1.00 89.39  ? 184 LEU B N   1 
ATOM 4682 C CA  . LEU D 4 184 ? 341.022 342.628 446.789 1.00 89.39  ? 184 LEU B CA  1 
ATOM 4683 C C   . LEU D 4 184 ? 340.133 342.727 445.561 1.00 89.39  ? 184 LEU B C   1 
ATOM 4684 O O   . LEU D 4 184 ? 339.142 341.998 445.483 1.00 89.39  ? 184 LEU B O   1 
ATOM 4685 C CB  . LEU D 4 184 ? 340.142 342.560 448.036 1.00 89.39  ? 184 LEU B CB  1 
ATOM 4686 C CG  . LEU D 4 184 ? 340.754 341.920 449.277 1.00 89.39  ? 184 LEU B CG  1 
ATOM 4687 C CD1 . LEU D 4 184 ? 339.732 341.846 450.385 1.00 89.39  ? 184 LEU B CD1 1 
ATOM 4688 C CD2 . LEU D 4 184 ? 341.271 340.546 448.948 1.00 89.39  ? 184 LEU B CD2 1 
ATOM 4689 N N   . THR D 4 185 ? 340.443 343.607 444.616 1.00 90.85  ? 185 THR B N   1 
ATOM 4690 C CA  . THR D 4 185 ? 339.661 343.737 443.398 1.00 90.85  ? 185 THR B CA  1 
ATOM 4691 C C   . THR D 4 185 ? 340.121 342.796 442.296 1.00 90.85  ? 185 THR B C   1 
ATOM 4692 O O   . THR D 4 185 ? 339.521 342.794 441.218 1.00 90.85  ? 185 THR B O   1 
ATOM 4693 C CB  . THR D 4 185 ? 339.719 345.175 442.890 1.00 90.85  ? 185 THR B CB  1 
ATOM 4694 O OG1 . THR D 4 185 ? 340.934 345.364 442.164 1.00 90.85  ? 185 THR B OG1 1 
ATOM 4695 C CG2 . THR D 4 185 ? 339.691 346.148 444.044 1.00 90.85  ? 185 THR B CG2 1 
ATOM 4696 N N   . ILE D 4 186 ? 341.164 342.001 442.532 1.00 93.27  ? 186 ILE B N   1 
ATOM 4697 C CA  . ILE D 4 186 ? 341.638 341.083 441.505 1.00 93.27  ? 186 ILE B CA  1 
ATOM 4698 C C   . ILE D 4 186 ? 340.736 339.858 441.390 1.00 93.27  ? 186 ILE B C   1 
ATOM 4699 O O   . ILE D 4 186 ? 340.520 339.358 440.280 1.00 93.27  ? 186 ILE B O   1 
ATOM 4700 C CB  . ILE D 4 186 ? 343.109 340.737 441.798 1.00 93.27  ? 186 ILE B CB  1 
ATOM 4701 C CG1 . ILE D 4 186 ? 343.668 339.718 440.806 1.00 93.27  ? 186 ILE B CG1 1 
ATOM 4702 C CG2 . ILE D 4 186 ? 343.272 340.272 443.209 1.00 93.27  ? 186 ILE B CG2 1 
ATOM 4703 C CD1 . ILE D 4 186 ? 345.097 339.335 441.080 1.00 93.27  ? 186 ILE B CD1 1 
ATOM 4704 N N   . PHE D 4 187 ? 340.156 339.397 442.494 1.00 94.79  ? 187 PHE B N   1 
ATOM 4705 C CA  . PHE D 4 187 ? 339.095 338.407 442.482 1.00 94.79  ? 187 PHE B CA  1 
ATOM 4706 C C   . PHE D 4 187 ? 337.851 339.002 441.827 1.00 94.79  ? 187 PHE B C   1 
ATOM 4707 O O   . PHE D 4 187 ? 337.718 340.225 441.750 1.00 94.79  ? 187 PHE B O   1 
ATOM 4708 C CB  . PHE D 4 187 ? 338.791 337.971 443.911 1.00 94.79  ? 187 PHE B CB  1 
ATOM 4709 C CG  . PHE D 4 187 ? 339.969 337.406 444.641 1.00 94.79  ? 187 PHE B CG  1 
ATOM 4710 C CD1 . PHE D 4 187 ? 340.676 336.343 444.121 1.00 94.79  ? 187 PHE B CD1 1 
ATOM 4711 C CD2 . PHE D 4 187 ? 340.349 337.924 445.863 1.00 94.79  ? 187 PHE B CD2 1 
ATOM 4712 C CE1 . PHE D 4 187 ? 341.748 335.819 444.797 1.00 94.79  ? 187 PHE B CE1 1 
ATOM 4713 C CE2 . PHE D 4 187 ? 341.419 337.404 446.541 1.00 94.79  ? 187 PHE B CE2 1 
ATOM 4714 C CZ  . PHE D 4 187 ? 342.118 336.351 446.008 1.00 94.79  ? 187 PHE B CZ  1 
ATOM 4715 N N   . PRO D 4 188 ? 336.937 338.170 441.316 1.00 96.50  ? 188 PRO B N   1 
ATOM 4716 C CA  . PRO D 4 188 ? 335.723 338.709 440.676 1.00 96.50  ? 188 PRO B CA  1 
ATOM 4717 C C   . PRO D 4 188 ? 334.832 339.450 441.660 1.00 96.50  ? 188 PRO B C   1 
ATOM 4718 O O   . PRO D 4 188 ? 334.384 338.895 442.662 1.00 96.50  ? 188 PRO B O   1 
ATOM 4719 C CB  . PRO D 4 188 ? 335.034 337.457 440.122 1.00 96.50  ? 188 PRO B CB  1 
ATOM 4720 C CG  . PRO D 4 188 ? 335.658 336.328 440.836 1.00 96.50  ? 188 PRO B CG  1 
ATOM 4721 C CD  . PRO D 4 188 ? 337.063 336.730 441.049 1.00 96.50  ? 188 PRO B CD  1 
ATOM 4722 N N   . HIS D 4 189 ? 334.578 340.721 441.361 1.00 94.53  ? 189 HIS B N   1 
ATOM 4723 C CA  . HIS D 4 189 ? 333.937 341.625 442.298 1.00 94.53  ? 189 HIS B CA  1 
ATOM 4724 C C   . HIS D 4 189 ? 332.969 342.540 441.564 1.00 94.53  ? 189 HIS B C   1 
ATOM 4725 O O   . HIS D 4 189 ? 332.804 342.459 440.346 1.00 94.53  ? 189 HIS B O   1 
ATOM 4726 C CB  . HIS D 4 189 ? 334.970 342.461 443.046 1.00 94.53  ? 189 HIS B CB  1 
ATOM 4727 C CG  . HIS D 4 189 ? 335.620 343.505 442.199 1.00 94.53  ? 189 HIS B CG  1 
ATOM 4728 N ND1 . HIS D 4 189 ? 336.312 343.202 441.047 1.00 94.53  ? 189 HIS B ND1 1 
ATOM 4729 C CD2 . HIS D 4 189 ? 335.686 344.848 442.335 1.00 94.53  ? 189 HIS B CD2 1 
ATOM 4730 C CE1 . HIS D 4 189 ? 336.776 344.315 440.509 1.00 94.53  ? 189 HIS B CE1 1 
ATOM 4731 N NE2 . HIS D 4 189 ? 336.411 345.328 441.272 1.00 94.53  ? 189 HIS B NE2 1 
ATOM 4732 N N   . GLN D 4 190 ? 332.340 343.431 442.332 1.00 101.47 ? 190 GLN B N   1 
ATOM 4733 C CA  . GLN D 4 190 ? 331.368 344.393 441.824 1.00 101.47 ? 190 GLN B CA  1 
ATOM 4734 C C   . GLN D 4 190 ? 331.177 345.468 442.881 1.00 101.47 ? 190 GLN B C   1 
ATOM 4735 O O   . GLN D 4 190 ? 331.112 345.154 444.071 1.00 101.47 ? 190 GLN B O   1 
ATOM 4736 C CB  . GLN D 4 190 ? 330.030 343.717 441.510 1.00 101.47 ? 190 GLN B CB  1 
ATOM 4737 C CG  . GLN D 4 190 ? 328.982 344.633 440.920 1.00 101.47 ? 190 GLN B CG  1 
ATOM 4738 C CD  . GLN D 4 190 ? 329.207 344.920 439.460 1.00 101.47 ? 190 GLN B CD  1 
ATOM 4739 O OE1 . GLN D 4 190 ? 329.725 345.972 439.097 1.00 101.47 ? 190 GLN B OE1 1 
ATOM 4740 N NE2 . GLN D 4 190 ? 328.802 343.991 438.608 1.00 101.47 ? 190 GLN B NE2 1 
ATOM 4741 N N   . TRP D 4 191 ? 331.089 346.722 442.456 1.00 100.81 ? 191 TRP B N   1 
ATOM 4742 C CA  . TRP D 4 191 ? 330.901 347.832 443.378 1.00 100.81 ? 191 TRP B CA  1 
ATOM 4743 C C   . TRP D 4 191 ? 329.425 348.171 443.523 1.00 100.81 ? 191 TRP B C   1 
ATOM 4744 O O   . TRP D 4 191 ? 328.667 348.133 442.552 1.00 100.81 ? 191 TRP B O   1 
ATOM 4745 C CB  . TRP D 4 191 ? 331.657 349.069 442.896 1.00 100.81 ? 191 TRP B CB  1 
ATOM 4746 C CG  . TRP D 4 191 ? 333.124 348.924 442.954 1.00 100.81 ? 191 TRP B CG  1 
ATOM 4747 C CD1 . TRP D 4 191 ? 333.944 348.518 441.951 1.00 100.81 ? 191 TRP B CD1 1 
ATOM 4748 C CD2 . TRP D 4 191 ? 333.960 349.179 444.080 1.00 100.81 ? 191 TRP B CD2 1 
ATOM 4749 N NE1 . TRP D 4 191 ? 335.245 348.504 442.382 1.00 100.81 ? 191 TRP B NE1 1 
ATOM 4750 C CE2 . TRP D 4 191 ? 335.279 348.905 443.689 1.00 100.81 ? 191 TRP B CE2 1 
ATOM 4751 C CE3 . TRP D 4 191 ? 333.722 349.611 445.383 1.00 100.81 ? 191 TRP B CE3 1 
ATOM 4752 C CZ2 . TRP D 4 191 ? 336.352 349.046 444.551 1.00 100.81 ? 191 TRP B CZ2 1 
ATOM 4753 C CZ3 . TRP D 4 191 ? 334.789 349.753 446.235 1.00 100.81 ? 191 TRP B CZ3 1 
ATOM 4754 C CH2 . TRP D 4 191 ? 336.087 349.473 445.816 1.00 100.81 ? 191 TRP B CH2 1 
ATOM 4755 N N   . ILE D 4 192 ? 329.026 348.512 444.742 1.00 104.74 ? 192 ILE B N   1 
ATOM 4756 C CA  . ILE D 4 192 ? 327.698 349.040 445.023 1.00 104.74 ? 192 ILE B CA  1 
ATOM 4757 C C   . ILE D 4 192 ? 327.887 350.439 445.586 1.00 104.74 ? 192 ILE B C   1 
ATOM 4758 O O   . ILE D 4 192 ? 328.266 350.607 446.751 1.00 104.74 ? 192 ILE B O   1 
ATOM 4759 C CB  . ILE D 4 192 ? 326.912 348.150 445.991 1.00 104.74 ? 192 ILE B CB  1 
ATOM 4760 C CG1 . ILE D 4 192 ? 326.670 346.779 445.369 1.00 104.74 ? 192 ILE B CG1 1 
ATOM 4761 C CG2 . ILE D 4 192 ? 325.581 348.782 446.327 1.00 104.74 ? 192 ILE B CG2 1 
ATOM 4762 C CD1 . ILE D 4 192 ? 325.884 345.849 446.250 1.00 104.74 ? 192 ILE B CD1 1 
ATOM 4763 N N   . ASN D 4 193 ? 327.651 351.443 444.751 1.00 108.84 ? 193 ASN B N   1 
ATOM 4764 C CA  . ASN D 4 193 ? 327.748 352.842 445.138 1.00 108.84 ? 193 ASN B CA  1 
ATOM 4765 C C   . ASN D 4 193 ? 326.341 353.407 445.195 1.00 108.84 ? 193 ASN B C   1 
ATOM 4766 O O   . ASN D 4 193 ? 325.648 353.443 444.175 1.00 108.84 ? 193 ASN B O   1 
ATOM 4767 C CB  . ASN D 4 193 ? 328.604 353.624 444.145 1.00 108.84 ? 193 ASN B CB  1 
ATOM 4768 C CG  . ASN D 4 193 ? 328.879 355.036 444.601 1.00 108.84 ? 193 ASN B CG  1 
ATOM 4769 O OD1 . ASN D 4 193 ? 328.678 355.376 445.763 1.00 108.84 ? 193 ASN B OD1 1 
ATOM 4770 N ND2 . ASN D 4 193 ? 329.350 355.870 443.685 1.00 108.84 ? 193 ASN B ND2 1 
ATOM 4771 N N   . LEU D 4 194 ? 325.932 353.872 446.379 1.00 108.46 ? 194 LEU B N   1 
ATOM 4772 C CA  . LEU D 4 194 ? 324.548 354.268 446.618 1.00 108.46 ? 194 LEU B CA  1 
ATOM 4773 C C   . LEU D 4 194 ? 324.137 355.524 445.864 1.00 108.46 ? 194 LEU B C   1 
ATOM 4774 O O   . LEU D 4 194 ? 322.941 355.823 445.803 1.00 108.46 ? 194 LEU B O   1 
ATOM 4775 C CB  . LEU D 4 194 ? 324.315 354.478 448.111 1.00 108.46 ? 194 LEU B CB  1 
ATOM 4776 C CG  . LEU D 4 194 ? 324.226 353.237 448.994 1.00 108.46 ? 194 LEU B CG  1 
ATOM 4777 C CD1 . LEU D 4 194 ? 323.636 353.607 450.331 1.00 108.46 ? 194 LEU B CD1 1 
ATOM 4778 C CD2 . LEU D 4 194 ? 323.400 352.160 448.340 1.00 108.46 ? 194 LEU B CD2 1 
ATOM 4779 N N   . ARG D 4 195 ? 325.086 356.266 445.303 1.00 108.82 ? 195 ARG B N   1 
ATOM 4780 C CA  . ARG D 4 195 ? 324.733 357.409 444.476 1.00 108.82 ? 195 ARG B CA  1 
ATOM 4781 C C   . ARG D 4 195 ? 324.145 356.963 443.144 1.00 108.82 ? 195 ARG B C   1 
ATOM 4782 O O   . ARG D 4 195 ? 323.141 357.518 442.687 1.00 108.82 ? 195 ARG B O   1 
ATOM 4783 C CB  . ARG D 4 195 ? 325.965 358.282 444.265 1.00 108.82 ? 195 ARG B CB  1 
ATOM 4784 C CG  . ARG D 4 195 ? 325.742 359.498 443.415 1.00 108.82 ? 195 ARG B CG  1 
ATOM 4785 C CD  . ARG D 4 195 ? 327.065 360.109 443.031 1.00 108.82 ? 195 ARG B CD  1 
ATOM 4786 N NE  . ARG D 4 195 ? 326.901 361.219 442.105 1.00 108.82 ? 195 ARG B NE  1 
ATOM 4787 C CZ  . ARG D 4 195 ? 326.748 362.479 442.485 1.00 108.82 ? 195 ARG B CZ  1 
ATOM 4788 N NH1 . ARG D 4 195 ? 326.741 362.782 443.773 1.00 108.82 ? 195 ARG B NH1 1 
ATOM 4789 N NH2 . ARG D 4 195 ? 326.606 363.434 441.579 1.00 108.82 ? 195 ARG B NH2 1 
ATOM 4790 N N   . THR D 4 196 ? 324.747 355.953 442.509 1.00 110.58 ? 196 THR B N   1 
ATOM 4791 C CA  . THR D 4 196 ? 324.323 355.512 441.186 1.00 110.58 ? 196 THR B CA  1 
ATOM 4792 C C   . THR D 4 196 ? 323.767 354.098 441.134 1.00 110.58 ? 196 THR B C   1 
ATOM 4793 O O   . THR D 4 196 ? 322.818 353.863 440.380 1.00 110.58 ? 196 THR B O   1 
ATOM 4794 C CB  . THR D 4 196 ? 325.486 355.588 440.184 1.00 110.58 ? 196 THR B CB  1 
ATOM 4795 O OG1 . THR D 4 196 ? 326.313 354.430 440.331 1.00 110.58 ? 196 THR B OG1 1 
ATOM 4796 C CG2 . THR D 4 196 ? 326.328 356.831 440.401 1.00 110.58 ? 196 THR B CG2 1 
ATOM 4797 N N   . ASN D 4 197 ? 324.314 353.156 441.894 1.00 109.40 ? 197 ASN B N   1 
ATOM 4798 C CA  . ASN D 4 197 ? 323.962 351.752 441.770 1.00 109.40 ? 197 ASN B CA  1 
ATOM 4799 C C   . ASN D 4 197 ? 323.220 351.298 443.017 1.00 109.40 ? 197 ASN B C   1 
ATOM 4800 O O   . ASN D 4 197 ? 323.174 352.000 444.027 1.00 109.40 ? 197 ASN B O   1 
ATOM 4801 C CB  . ASN D 4 197 ? 325.206 350.888 441.558 1.00 109.40 ? 197 ASN B CB  1 
ATOM 4802 C CG  . ASN D 4 197 ? 324.921 349.652 440.748 1.00 109.40 ? 197 ASN B CG  1 
ATOM 4803 O OD1 . ASN D 4 197 ? 323.903 349.569 440.065 1.00 109.40 ? 197 ASN B OD1 1 
ATOM 4804 N ND2 . ASN D 4 197 ? 325.818 348.678 440.817 1.00 109.40 ? 197 ASN B ND2 1 
ATOM 4805 N N   . ASN D 4 198 ? 322.615 350.118 442.936 1.00 108.09 ? 198 ASN B N   1 
ATOM 4806 C CA  . ASN D 4 198 ? 321.874 349.610 444.080 1.00 108.09 ? 198 ASN B CA  1 
ATOM 4807 C C   . ASN D 4 198 ? 322.221 348.166 444.413 1.00 108.09 ? 198 ASN B C   1 
ATOM 4808 O O   . ASN D 4 198 ? 322.165 347.767 445.579 1.00 108.09 ? 198 ASN B O   1 
ATOM 4809 C CB  . ASN D 4 198 ? 320.376 349.736 443.830 1.00 108.09 ? 198 ASN B CB  1 
ATOM 4810 C CG  . ASN D 4 198 ? 319.565 349.441 445.059 1.00 108.09 ? 198 ASN B CG  1 
ATOM 4811 O OD1 . ASN D 4 198 ? 318.577 348.712 445.006 1.00 108.09 ? 198 ASN B OD1 1 
ATOM 4812 N ND2 . ASN D 4 198 ? 319.987 349.994 446.185 1.00 108.09 ? 198 ASN B ND2 1 
ATOM 4813 N N   . SER D 4 199 ? 322.586 347.374 443.410 1.00 106.07 ? 199 SER B N   1 
ATOM 4814 C CA  . SER D 4 199 ? 322.716 345.939 443.598 1.00 106.07 ? 199 SER B CA  1 
ATOM 4815 C C   . SER D 4 199 ? 323.925 345.409 442.845 1.00 106.07 ? 199 SER B C   1 
ATOM 4816 O O   . SER D 4 199 ? 324.484 346.073 441.971 1.00 106.07 ? 199 SER B O   1 
ATOM 4817 C CB  . SER D 4 199 ? 321.464 345.205 443.124 1.00 106.07 ? 199 SER B CB  1 
ATOM 4818 O OG  . SER D 4 199 ? 321.322 345.323 441.722 1.00 106.07 ? 199 SER B OG  1 
ATOM 4819 N N   . ALA D 4 200 ? 324.307 344.184 443.194 1.00 99.36  ? 200 ALA B N   1 
ATOM 4820 C CA  . ALA D 4 200 ? 325.392 343.466 442.548 1.00 99.36  ? 200 ALA B CA  1 
ATOM 4821 C C   . ALA D 4 200 ? 324.914 342.067 442.194 1.00 99.36  ? 200 ALA B C   1 
ATOM 4822 O O   . ALA D 4 200 ? 323.930 341.572 442.743 1.00 99.36  ? 200 ALA B O   1 
ATOM 4823 C CB  . ALA D 4 200 ? 326.623 343.383 443.448 1.00 99.36  ? 200 ALA B CB  1 
ATOM 4824 N N   . THR D 4 201 ? 325.612 341.431 441.258 1.00 101.05 ? 201 THR B N   1 
ATOM 4825 C CA  . THR D 4 201 ? 325.259 340.081 440.832 1.00 101.05 ? 201 THR B CA  1 
ATOM 4826 C C   . THR D 4 201 ? 326.514 339.372 440.358 1.00 101.05 ? 201 THR B C   1 
ATOM 4827 O O   . THR D 4 201 ? 327.180 339.848 439.437 1.00 101.05 ? 201 THR B O   1 
ATOM 4828 C CB  . THR D 4 201 ? 324.214 340.097 439.717 1.00 101.05 ? 201 THR B CB  1 
ATOM 4829 O OG1 . THR D 4 201 ? 323.017 340.731 440.179 1.00 101.05 ? 201 THR B OG1 1 
ATOM 4830 C CG2 . THR D 4 201 ? 323.890 338.684 439.280 1.00 101.05 ? 201 THR B CG2 1 
ATOM 4831 N N   . LEU D 4 202 ? 326.826 338.239 440.973 1.00 99.18  ? 202 LEU B N   1 
ATOM 4832 C CA  . LEU D 4 202 ? 327.995 337.449 440.627 1.00 99.18  ? 202 LEU B CA  1 
ATOM 4833 C C   . LEU D 4 202 ? 327.552 336.057 440.208 1.00 99.18  ? 202 LEU B C   1 
ATOM 4834 O O   . LEU D 4 202 ? 326.598 335.510 440.764 1.00 99.18  ? 202 LEU B O   1 
ATOM 4835 C CB  . LEU D 4 202 ? 328.958 337.348 441.805 1.00 99.18  ? 202 LEU B CB  1 
ATOM 4836 C CG  . LEU D 4 202 ? 329.417 338.659 442.432 1.00 99.18  ? 202 LEU B CG  1 
ATOM 4837 C CD1 . LEU D 4 202 ? 329.780 338.440 443.875 1.00 99.18  ? 202 LEU B CD1 1 
ATOM 4838 C CD2 . LEU D 4 202 ? 330.610 339.181 441.689 1.00 99.18  ? 202 LEU B CD2 1 
ATOM 4839 N N   . VAL D 4 203 ? 328.239 335.492 439.223 1.00 103.42 ? 203 VAL B N   1 
ATOM 4840 C CA  . VAL D 4 203 ? 328.033 334.113 438.796 1.00 103.42 ? 203 VAL B CA  1 
ATOM 4841 C C   . VAL D 4 203 ? 329.386 333.428 438.837 1.00 103.42 ? 203 VAL B C   1 
ATOM 4842 O O   . VAL D 4 203 ? 330.303 333.824 438.110 1.00 103.42 ? 203 VAL B O   1 
ATOM 4843 C CB  . VAL D 4 203 ? 327.427 334.027 437.391 1.00 103.42 ? 203 VAL B CB  1 
ATOM 4844 C CG1 . VAL D 4 203 ? 327.434 332.596 436.916 1.00 103.42 ? 203 VAL B CG1 1 
ATOM 4845 C CG2 . VAL D 4 203 ? 326.024 334.578 437.387 1.00 103.42 ? 203 VAL B CG2 1 
ATOM 4846 N N   . MET D 4 204 ? 329.516 332.407 439.676 1.00 109.08 ? 204 MET B N   1 
ATOM 4847 C CA  . MET D 4 204 ? 330.821 331.833 439.974 1.00 109.08 ? 204 MET B CA  1 
ATOM 4848 C C   . MET D 4 204 ? 330.875 330.359 439.605 1.00 109.08 ? 204 MET B C   1 
ATOM 4849 O O   . MET D 4 204 ? 330.005 329.584 440.036 1.00 109.08 ? 204 MET B O   1 
ATOM 4850 C CB  . MET D 4 204 ? 331.143 332.022 441.448 1.00 109.08 ? 204 MET B CB  1 
ATOM 4851 C CG  . MET D 4 204 ? 331.264 333.466 441.825 1.00 109.08 ? 204 MET B CG  1 
ATOM 4852 S SD  . MET D 4 204 ? 332.732 334.174 441.085 1.00 109.08 ? 204 MET B SD  1 
ATOM 4853 C CE  . MET D 4 204 ? 333.981 333.091 441.762 1.00 109.08 ? 204 MET B CE  1 
ATOM 4854 N N   . PRO D 4 205 ? 331.860 329.924 438.834 1.00 104.59 ? 205 PRO B N   1 
ATOM 4855 C CA  . PRO D 4 205 ? 331.980 328.511 438.480 1.00 104.59 ? 205 PRO B CA  1 
ATOM 4856 C C   . PRO D 4 205 ? 332.654 327.725 439.599 1.00 104.59 ? 205 PRO B C   1 
ATOM 4857 O O   . PRO D 4 205 ? 332.997 328.256 440.649 1.00 104.59 ? 205 PRO B O   1 
ATOM 4858 C CB  . PRO D 4 205 ? 332.845 328.554 437.226 1.00 104.59 ? 205 PRO B CB  1 
ATOM 4859 C CG  . PRO D 4 205 ? 333.703 329.734 437.430 1.00 104.59 ? 205 PRO B CG  1 
ATOM 4860 C CD  . PRO D 4 205 ? 332.880 330.743 438.162 1.00 104.59 ? 205 PRO B CD  1 
ATOM 4861 N N   . TYR D 4 206 ? 332.842 326.434 439.350 1.00 104.84 ? 206 TYR B N   1 
ATOM 4862 C CA  . TYR D 4 206 ? 333.486 325.551 440.312 1.00 104.84 ? 206 TYR B CA  1 
ATOM 4863 C C   . TYR D 4 206 ? 334.992 325.600 440.105 1.00 104.84 ? 206 TYR B C   1 
ATOM 4864 O O   . TYR D 4 206 ? 335.491 325.173 439.059 1.00 104.84 ? 206 TYR B O   1 
ATOM 4865 C CB  . TYR D 4 206 ? 332.959 324.130 440.147 1.00 104.84 ? 206 TYR B CB  1 
ATOM 4866 C CG  . TYR D 4 206 ? 333.581 323.113 441.066 1.00 104.84 ? 206 TYR B CG  1 
ATOM 4867 C CD1 . TYR D 4 206 ? 333.224 323.049 442.400 1.00 104.84 ? 206 TYR B CD1 1 
ATOM 4868 C CD2 . TYR D 4 206 ? 334.511 322.200 440.593 1.00 104.84 ? 206 TYR B CD2 1 
ATOM 4869 C CE1 . TYR D 4 206 ? 333.787 322.117 443.240 1.00 104.84 ? 206 TYR B CE1 1 
ATOM 4870 C CE2 . TYR D 4 206 ? 335.078 321.266 441.427 1.00 104.84 ? 206 TYR B CE2 1 
ATOM 4871 C CZ  . TYR D 4 206 ? 334.711 321.232 442.747 1.00 104.84 ? 206 TYR B CZ  1 
ATOM 4872 O OH  . TYR D 4 206 ? 335.271 320.304 443.583 1.00 104.84 ? 206 TYR B OH  1 
ATOM 4873 N N   . ILE D 4 207 ? 335.718 326.114 441.093 1.00 100.82 ? 207 ILE B N   1 
ATOM 4874 C CA  . ILE D 4 207 ? 337.161 326.307 440.998 1.00 100.82 ? 207 ILE B CA  1 
ATOM 4875 C C   . ILE D 4 207 ? 337.811 325.430 442.058 1.00 100.82 ? 207 ILE B C   1 
ATOM 4876 O O   . ILE D 4 207 ? 337.832 325.783 443.242 1.00 100.82 ? 207 ILE B O   1 
ATOM 4877 C CB  . ILE D 4 207 ? 337.561 327.773 441.177 1.00 100.82 ? 207 ILE B CB  1 
ATOM 4878 C CG1 . ILE D 4 207 ? 336.815 328.655 440.183 1.00 100.82 ? 207 ILE B CG1 1 
ATOM 4879 C CG2 . ILE D 4 207 ? 339.045 327.939 440.982 1.00 100.82 ? 207 ILE B CG2 1 
ATOM 4880 C CD1 . ILE D 4 207 ? 336.965 330.122 440.461 1.00 100.82 ? 207 ILE B CD1 1 
ATOM 4881 N N   . ASN D 4 208 ? 338.352 324.291 441.641 1.00 104.83 ? 208 ASN B N   1 
ATOM 4882 C CA  . ASN D 4 208 ? 339.061 323.402 442.548 1.00 104.83 ? 208 ASN B CA  1 
ATOM 4883 C C   . ASN D 4 208 ? 340.056 322.591 441.736 1.00 104.83 ? 208 ASN B C   1 
ATOM 4884 O O   . ASN D 4 208 ? 339.947 322.488 440.513 1.00 104.83 ? 208 ASN B O   1 
ATOM 4885 C CB  . ASN D 4 208 ? 338.099 322.484 443.306 1.00 104.83 ? 208 ASN B CB  1 
ATOM 4886 C CG  . ASN D 4 208 ? 338.676 321.984 444.612 1.00 104.83 ? 208 ASN B CG  1 
ATOM 4887 O OD1 . ASN D 4 208 ? 339.890 321.904 444.777 1.00 104.83 ? 208 ASN B OD1 1 
ATOM 4888 N ND2 . ASN D 4 208 ? 337.805 321.640 445.548 1.00 104.83 ? 208 ASN B ND2 1 
ATOM 4889 N N   . SER D 4 209 ? 341.033 322.012 442.435 1.00 106.64 ? 209 SER B N   1 
ATOM 4890 C CA  . SER D 4 209 ? 342.059 321.234 441.755 1.00 106.64 ? 209 SER B CA  1 
ATOM 4891 C C   . SER D 4 209 ? 341.542 319.863 441.343 1.00 106.64 ? 209 SER B C   1 
ATOM 4892 O O   . SER D 4 209 ? 341.886 319.367 440.267 1.00 106.64 ? 209 SER B O   1 
ATOM 4893 C CB  . SER D 4 209 ? 343.287 321.089 442.649 1.00 106.64 ? 209 SER B CB  1 
ATOM 4894 O OG  . SER D 4 209 ? 343.039 320.186 443.707 1.00 106.64 ? 209 SER B OG  1 
ATOM 4895 N N   . VAL D 4 210 ? 340.718 319.241 442.176 1.00 106.01 ? 210 VAL B N   1 
ATOM 4896 C CA  . VAL D 4 210 ? 340.157 317.928 441.878 1.00 106.01 ? 210 VAL B CA  1 
ATOM 4897 C C   . VAL D 4 210 ? 338.796 318.127 441.225 1.00 106.01 ? 210 VAL B C   1 
ATOM 4898 O O   . VAL D 4 210 ? 338.125 319.128 441.508 1.00 106.01 ? 210 VAL B O   1 
ATOM 4899 C CB  . VAL D 4 210 ? 340.069 317.072 443.148 1.00 106.01 ? 210 VAL B CB  1 
ATOM 4900 C CG1 . VAL D 4 210 ? 341.443 316.601 443.537 1.00 106.01 ? 210 VAL B CG1 1 
ATOM 4901 C CG2 . VAL D 4 210 ? 339.462 317.872 444.275 1.00 106.01 ? 210 VAL B CG2 1 
ATOM 4902 N N   . PRO D 4 211 ? 338.352 317.232 440.337 1.00 111.26 ? 211 PRO B N   1 
ATOM 4903 C CA  . PRO D 4 211 ? 337.096 317.488 439.617 1.00 111.26 ? 211 PRO B CA  1 
ATOM 4904 C C   . PRO D 4 211 ? 335.848 317.300 440.454 1.00 111.26 ? 211 PRO B C   1 
ATOM 4905 O O   . PRO D 4 211 ? 334.784 317.775 440.046 1.00 111.26 ? 211 PRO B O   1 
ATOM 4906 C CB  . PRO D 4 211 ? 337.141 316.480 438.465 1.00 111.26 ? 211 PRO B CB  1 
ATOM 4907 C CG  . PRO D 4 211 ? 338.005 315.398 438.959 1.00 111.26 ? 211 PRO B CG  1 
ATOM 4908 C CD  . PRO D 4 211 ? 339.054 316.059 439.791 1.00 111.26 ? 211 PRO B CD  1 
ATOM 4909 N N   . MET D 4 212 ? 335.931 316.629 441.597 1.00 118.31 ? 212 MET B N   1 
ATOM 4910 C CA  . MET D 4 212 ? 334.778 316.451 442.464 1.00 118.31 ? 212 MET B CA  1 
ATOM 4911 C C   . MET D 4 212 ? 335.285 316.231 443.877 1.00 118.31 ? 212 MET B C   1 
ATOM 4912 O O   . MET D 4 212 ? 336.095 315.331 444.106 1.00 118.31 ? 212 MET B O   1 
ATOM 4913 C CB  . MET D 4 212 ? 333.925 315.271 441.997 1.00 118.31 ? 212 MET B CB  1 
ATOM 4914 C CG  . MET D 4 212 ? 332.582 315.164 442.666 1.00 118.31 ? 212 MET B CG  1 
ATOM 4915 S SD  . MET D 4 212 ? 331.640 313.785 441.995 1.00 118.31 ? 212 MET B SD  1 
ATOM 4916 C CE  . MET D 4 212 ? 331.280 314.415 440.362 1.00 118.31 ? 212 MET B CE  1 
ATOM 4917 N N   . ASP D 4 213 ? 334.822 317.045 444.819 1.00 116.72 ? 213 ASP B N   1 
ATOM 4918 C CA  . ASP D 4 213 ? 335.437 317.102 446.134 1.00 116.72 ? 213 ASP B CA  1 
ATOM 4919 C C   . ASP D 4 213 ? 334.360 317.018 447.208 1.00 116.72 ? 213 ASP B C   1 
ATOM 4920 O O   . ASP D 4 213 ? 333.168 317.156 446.930 1.00 116.72 ? 213 ASP B O   1 
ATOM 4921 C CB  . ASP D 4 213 ? 336.263 318.387 446.275 1.00 116.72 ? 213 ASP B CB  1 
ATOM 4922 C CG  . ASP D 4 213 ? 337.301 318.310 447.377 1.00 116.72 ? 213 ASP B CG  1 
ATOM 4923 O OD1 . ASP D 4 213 ? 337.353 317.276 448.075 1.00 116.72 ? 213 ASP B OD1 1 
ATOM 4924 O OD2 . ASP D 4 213 ? 338.072 319.279 447.536 1.00 116.72 ? 213 ASP B OD2 1 
ATOM 4925 N N   . ASN D 4 214 ? 334.797 316.773 448.440 1.00 117.59 ? 214 ASN B N   1 
ATOM 4926 C CA  . ASN D 4 214 ? 333.885 316.675 449.569 1.00 117.59 ? 214 ASN B CA  1 
ATOM 4927 C C   . ASN D 4 214 ? 333.332 318.049 449.925 1.00 117.59 ? 214 ASN B C   1 
ATOM 4928 O O   . ASN D 4 214 ? 333.999 319.068 449.738 1.00 117.59 ? 214 ASN B O   1 
ATOM 4929 C CB  . ASN D 4 214 ? 334.611 316.069 450.766 1.00 117.59 ? 214 ASN B CB  1 
ATOM 4930 C CG  . ASN D 4 214 ? 333.690 315.787 451.920 1.00 117.59 ? 214 ASN B CG  1 
ATOM 4931 O OD1 . ASN D 4 214 ? 333.464 316.645 452.768 1.00 117.59 ? 214 ASN B OD1 1 
ATOM 4932 N ND2 . ASN D 4 214 ? 333.146 314.580 451.961 1.00 117.59 ? 214 ASN B ND2 1 
ATOM 4933 N N   . MET D 4 215 ? 332.104 318.076 450.438 1.00 117.66 ? 215 MET B N   1 
ATOM 4934 C CA  . MET D 4 215 ? 331.415 319.324 450.727 1.00 117.66 ? 215 MET B CA  1 
ATOM 4935 C C   . MET D 4 215 ? 331.346 319.644 452.211 1.00 117.66 ? 215 MET B C   1 
ATOM 4936 O O   . MET D 4 215 ? 330.719 320.637 452.587 1.00 117.66 ? 215 MET B O   1 
ATOM 4937 C CB  . MET D 4 215 ? 330.003 319.297 450.146 1.00 117.66 ? 215 MET B CB  1 
ATOM 4938 C CG  . MET D 4 215 ? 329.920 318.706 448.760 1.00 117.66 ? 215 MET B CG  1 
ATOM 4939 S SD  . MET D 4 215 ? 328.455 319.251 447.874 1.00 117.66 ? 215 MET B SD  1 
ATOM 4940 C CE  . MET D 4 215 ? 328.934 320.926 447.492 1.00 117.66 ? 215 MET B CE  1 
ATOM 4941 N N   . PHE D 4 216 ? 331.963 318.838 453.067 1.00 114.87 ? 216 PHE B N   1 
ATOM 4942 C CA  . PHE D 4 216 ? 331.952 319.117 454.495 1.00 114.87 ? 216 PHE B CA  1 
ATOM 4943 C C   . PHE D 4 216 ? 333.289 319.572 455.043 1.00 114.87 ? 216 PHE B C   1 
ATOM 4944 O O   . PHE D 4 216 ? 333.314 320.315 456.024 1.00 114.87 ? 216 PHE B O   1 
ATOM 4945 C CB  . PHE D 4 216 ? 331.500 317.886 455.283 1.00 114.87 ? 216 PHE B CB  1 
ATOM 4946 C CG  . PHE D 4 216 ? 330.047 317.897 455.629 1.00 114.87 ? 216 PHE B CG  1 
ATOM 4947 C CD1 . PHE D 4 216 ? 329.541 318.854 456.492 1.00 114.87 ? 216 PHE B CD1 1 
ATOM 4948 C CD2 . PHE D 4 216 ? 329.190 316.947 455.110 1.00 114.87 ? 216 PHE B CD2 1 
ATOM 4949 C CE1 . PHE D 4 216 ? 328.203 318.871 456.820 1.00 114.87 ? 216 PHE B CE1 1 
ATOM 4950 C CE2 . PHE D 4 216 ? 327.851 316.957 455.437 1.00 114.87 ? 216 PHE B CE2 1 
ATOM 4951 C CZ  . PHE D 4 216 ? 327.359 317.922 456.293 1.00 114.87 ? 216 PHE B CZ  1 
ATOM 4952 N N   . ARG D 4 217 ? 334.396 319.141 454.448 1.00 114.23 ? 217 ARG B N   1 
ATOM 4953 C CA  . ARG D 4 217 ? 335.721 319.489 454.929 1.00 114.23 ? 217 ARG B CA  1 
ATOM 4954 C C   . ARG D 4 217 ? 336.394 320.545 454.067 1.00 114.23 ? 217 ARG B C   1 
ATOM 4955 O O   . ARG D 4 217 ? 337.606 320.740 454.176 1.00 114.23 ? 217 ARG B O   1 
ATOM 4956 C CB  . ARG D 4 217 ? 336.592 318.236 455.008 1.00 114.23 ? 217 ARG B CB  1 
ATOM 4957 C CG  . ARG D 4 217 ? 336.295 317.362 456.213 1.00 114.23 ? 217 ARG B CG  1 
ATOM 4958 C CD  . ARG D 4 217 ? 337.218 316.156 456.288 1.00 114.23 ? 217 ARG B CD  1 
ATOM 4959 N NE  . ARG D 4 217 ? 337.143 315.493 457.588 1.00 114.23 ? 217 ARG B NE  1 
ATOM 4960 C CZ  . ARG D 4 217 ? 338.143 315.435 458.462 1.00 114.23 ? 217 ARG B CZ  1 
ATOM 4961 N NH1 . ARG D 4 217 ? 339.308 315.996 458.181 1.00 114.23 ? 217 ARG B NH1 1 
ATOM 4962 N NH2 . ARG D 4 217 ? 337.980 314.811 459.618 1.00 114.23 ? 217 ARG B NH2 1 
ATOM 4963 N N   . HIS D 4 218 ? 335.638 321.237 453.219 1.00 110.56 ? 218 HIS B N   1 
ATOM 4964 C CA  . HIS D 4 218 ? 336.234 322.156 452.260 1.00 110.56 ? 218 HIS B CA  1 
ATOM 4965 C C   . HIS D 4 218 ? 335.228 323.228 451.881 1.00 110.56 ? 218 HIS B C   1 
ATOM 4966 O O   . HIS D 4 218 ? 334.089 322.912 451.531 1.00 110.56 ? 218 HIS B O   1 
ATOM 4967 C CB  . HIS D 4 218 ? 336.695 321.410 451.009 1.00 110.56 ? 218 HIS B CB  1 
ATOM 4968 C CG  . HIS D 4 218 ? 337.715 322.151 450.206 1.00 110.56 ? 218 HIS B CG  1 
ATOM 4969 N ND1 . HIS D 4 218 ? 338.328 321.606 449.100 1.00 110.56 ? 218 HIS B ND1 1 
ATOM 4970 C CD2 . HIS D 4 218 ? 338.232 323.393 450.348 1.00 110.56 ? 218 HIS B CD2 1 
ATOM 4971 C CE1 . HIS D 4 218 ? 339.177 322.481 448.594 1.00 110.56 ? 218 HIS B CE1 1 
ATOM 4972 N NE2 . HIS D 4 218 ? 339.138 323.574 449.333 1.00 110.56 ? 218 HIS B NE2 1 
ATOM 4973 N N   . ASN D 4 219 ? 335.655 324.485 451.941 1.00 107.44 ? 219 ASN B N   1 
ATOM 4974 C CA  . ASN D 4 219 ? 334.857 325.634 451.524 1.00 107.44 ? 219 ASN B CA  1 
ATOM 4975 C C   . ASN D 4 219 ? 335.624 326.318 450.402 1.00 107.44 ? 219 ASN B C   1 
ATOM 4976 O O   . ASN D 4 219 ? 336.569 327.068 450.652 1.00 107.44 ? 219 ASN B O   1 
ATOM 4977 C CB  . ASN D 4 219 ? 334.609 326.576 452.673 1.00 107.44 ? 219 ASN B CB  1 
ATOM 4978 C CG  . ASN D 4 219 ? 334.016 325.886 453.864 1.00 107.44 ? 219 ASN B CG  1 
ATOM 4979 O OD1 . ASN D 4 219 ? 333.278 324.915 453.726 1.00 107.44 ? 219 ASN B OD1 1 
ATOM 4980 N ND2 . ASN D 4 219 ? 334.334 326.379 455.050 1.00 107.44 ? 219 ASN B ND2 1 
ATOM 4981 N N   . ASN D 4 220 ? 335.216 326.072 449.165 1.00 104.79 ? 220 ASN B N   1 
ATOM 4982 C CA  . ASN D 4 220 ? 335.991 326.556 448.035 1.00 104.79 ? 220 ASN B CA  1 
ATOM 4983 C C   . ASN D 4 220 ? 335.725 328.014 447.697 1.00 104.79 ? 220 ASN B C   1 
ATOM 4984 O O   . ASN D 4 220 ? 336.376 328.541 446.793 1.00 104.79 ? 220 ASN B O   1 
ATOM 4985 C CB  . ASN D 4 220 ? 335.723 325.695 446.803 1.00 104.79 ? 220 ASN B CB  1 
ATOM 4986 C CG  . ASN D 4 220 ? 334.259 325.442 446.585 1.00 104.79 ? 220 ASN B CG  1 
ATOM 4987 O OD1 . ASN D 4 220 ? 333.424 325.883 447.366 1.00 104.79 ? 220 ASN B OD1 1 
ATOM 4988 N ND2 . ASN D 4 220 ? 333.933 324.734 445.516 1.00 104.79 ? 220 ASN B ND2 1 
ATOM 4989 N N   . LEU D 4 221 ? 334.804 328.683 448.384 1.00 99.23  ? 221 LEU B N   1 
ATOM 4990 C CA  . LEU D 4 221 ? 334.517 330.080 448.102 1.00 99.23  ? 221 LEU B CA  1 
ATOM 4991 C C   . LEU D 4 221 ? 334.380 330.838 449.410 1.00 99.23  ? 221 LEU B C   1 
ATOM 4992 O O   . LEU D 4 221 ? 334.393 330.253 450.493 1.00 99.23  ? 221 LEU B O   1 
ATOM 4993 C CB  . LEU D 4 221 ? 333.244 330.245 447.266 1.00 99.23  ? 221 LEU B CB  1 
ATOM 4994 C CG  . LEU D 4 221 ? 333.359 329.933 445.775 1.00 99.23  ? 221 LEU B CG  1 
ATOM 4995 C CD1 . LEU D 4 221 ? 332.069 330.246 445.067 1.00 99.23  ? 221 LEU B CD1 1 
ATOM 4996 C CD2 . LEU D 4 221 ? 334.488 330.712 445.152 1.00 99.23  ? 221 LEU B CD2 1 
ATOM 4997 N N   . THR D 4 222 ? 334.250 332.156 449.291 1.00 96.87  ? 222 THR B N   1 
ATOM 4998 C CA  . THR D 4 222 ? 334.067 333.042 450.436 1.00 96.87  ? 222 THR B CA  1 
ATOM 4999 C C   . THR D 4 222 ? 333.497 334.347 449.915 1.00 96.87  ? 222 THR B C   1 
ATOM 5000 O O   . THR D 4 222 ? 334.108 334.982 449.055 1.00 96.87  ? 222 THR B O   1 
ATOM 5001 C CB  . THR D 4 222 ? 335.384 333.297 451.172 1.00 96.87  ? 222 THR B CB  1 
ATOM 5002 O OG1 . THR D 4 222 ? 335.785 332.110 451.863 1.00 96.87  ? 222 THR B OG1 1 
ATOM 5003 C CG2 . THR D 4 222 ? 335.232 334.421 452.178 1.00 96.87  ? 222 THR B CG2 1 
ATOM 5004 N N   . LEU D 4 223 ? 332.341 334.745 450.423 1.00 94.25  ? 223 LEU B N   1 
ATOM 5005 C CA  . LEU D 4 223 ? 331.677 335.969 449.994 1.00 94.25  ? 223 LEU B CA  1 
ATOM 5006 C C   . LEU D 4 223 ? 331.945 337.051 451.030 1.00 94.25  ? 223 LEU B C   1 
ATOM 5007 O O   . LEU D 4 223 ? 331.580 336.896 452.196 1.00 94.25  ? 223 LEU B O   1 
ATOM 5008 C CB  . LEU D 4 223 ? 330.181 335.729 449.825 1.00 94.25  ? 223 LEU B CB  1 
ATOM 5009 C CG  . LEU D 4 223 ? 329.329 336.979 449.681 1.00 94.25  ? 223 LEU B CG  1 
ATOM 5010 C CD1 . LEU D 4 223 ? 329.592 337.617 448.346 1.00 94.25  ? 223 LEU B CD1 1 
ATOM 5011 C CD2 . LEU D 4 223 ? 327.877 336.611 449.811 1.00 94.25  ? 223 LEU B CD2 1 
ATOM 5012 N N   . MET D 4 224 ? 332.579 338.142 450.611 1.00 95.77  ? 224 MET B N   1 
ATOM 5013 C CA  . MET D 4 224 ? 332.937 339.237 451.501 1.00 95.77  ? 224 MET B CA  1 
ATOM 5014 C C   . MET D 4 224 ? 332.220 340.513 451.092 1.00 95.77  ? 224 MET B C   1 
ATOM 5015 O O   . MET D 4 224 ? 332.048 340.792 449.905 1.00 95.77  ? 224 MET B O   1 
ATOM 5016 C CB  . MET D 4 224 ? 334.443 339.495 451.490 1.00 95.77  ? 224 MET B CB  1 
ATOM 5017 C CG  . MET D 4 224 ? 335.283 338.356 452.004 1.00 95.77  ? 224 MET B CG  1 
ATOM 5018 S SD  . MET D 4 224 ? 337.031 338.673 451.750 1.00 95.77  ? 224 MET B SD  1 
ATOM 5019 C CE  . MET D 4 224 ? 337.744 337.543 452.933 1.00 95.77  ? 224 MET B CE  1 
ATOM 5020 N N   . ILE D 4 225 ? 331.809 341.289 452.089 1.00 89.62  ? 225 ILE B N   1 
ATOM 5021 C CA  . ILE D 4 225 ? 331.180 342.588 451.883 1.00 89.62  ? 225 ILE B CA  1 
ATOM 5022 C C   . ILE D 4 225 ? 331.870 343.570 452.813 1.00 89.62  ? 225 ILE B C   1 
ATOM 5023 O O   . ILE D 4 225 ? 331.776 343.430 454.035 1.00 89.62  ? 225 ILE B O   1 
ATOM 5024 C CB  . ILE D 4 225 ? 329.671 342.555 452.169 1.00 89.62  ? 225 ILE B CB  1 
ATOM 5025 C CG1 . ILE D 4 225 ? 328.933 341.716 451.134 1.00 89.62  ? 225 ILE B CG1 1 
ATOM 5026 C CG2 . ILE D 4 225 ? 329.108 343.949 452.169 1.00 89.62  ? 225 ILE B CG2 1 
ATOM 5027 C CD1 . ILE D 4 225 ? 327.511 341.436 451.504 1.00 89.62  ? 225 ILE B CD1 1 
ATOM 5028 N N   . ILE D 4 226 ? 332.575 344.551 452.247 1.00 95.74  ? 226 ILE B N   1 
ATOM 5029 C CA  . ILE D 4 226 ? 333.385 345.480 453.020 1.00 95.74  ? 226 ILE B CA  1 
ATOM 5030 C C   . ILE D 4 226 ? 332.974 346.911 452.697 1.00 95.74  ? 226 ILE B C   1 
ATOM 5031 O O   . ILE D 4 226 ? 333.023 347.318 451.533 1.00 95.74  ? 226 ILE B O   1 
ATOM 5032 C CB  . ILE D 4 226 ? 334.890 345.297 452.763 1.00 95.74  ? 226 ILE B CB  1 
ATOM 5033 C CG1 . ILE D 4 226 ? 335.351 343.924 453.229 1.00 95.74  ? 226 ILE B CG1 1 
ATOM 5034 C CG2 . ILE D 4 226 ? 335.677 346.350 453.493 1.00 95.74  ? 226 ILE B CG2 1 
ATOM 5035 C CD1 . ILE D 4 226 ? 336.791 343.654 452.945 1.00 95.74  ? 226 ILE B CD1 1 
ATOM 5036 N N   . PRO D 4 227 ? 332.563 347.711 453.678 1.00 96.13  ? 227 PRO B N   1 
ATOM 5037 C CA  . PRO D 4 227 ? 332.261 349.126 453.433 1.00 96.13  ? 227 PRO B CA  1 
ATOM 5038 C C   . PRO D 4 227 ? 333.525 349.968 453.452 1.00 96.13  ? 227 PRO B C   1 
ATOM 5039 O O   . PRO D 4 227 ? 334.119 350.196 454.509 1.00 96.13  ? 227 PRO B O   1 
ATOM 5040 C CB  . PRO D 4 227 ? 331.324 349.484 454.595 1.00 96.13  ? 227 PRO B CB  1 
ATOM 5041 C CG  . PRO D 4 227 ? 331.087 348.213 455.341 1.00 96.13  ? 227 PRO B CG  1 
ATOM 5042 C CD  . PRO D 4 227 ? 332.229 347.331 455.051 1.00 96.13  ? 227 PRO B CD  1 
ATOM 5043 N N   . PHE D 4 228 ? 333.931 350.453 452.278 1.00 99.01  ? 228 PHE B N   1 
ATOM 5044 C CA  . PHE D 4 228 ? 335.058 351.377 452.218 1.00 99.01  ? 228 PHE B CA  1 
ATOM 5045 C C   . PHE D 4 228 ? 334.658 352.764 452.692 1.00 99.01  ? 228 PHE B C   1 
ATOM 5046 O O   . PHE D 4 228 ? 335.177 353.263 453.694 1.00 99.01  ? 228 PHE B O   1 
ATOM 5047 C CB  . PHE D 4 228 ? 335.624 351.440 450.801 1.00 99.01  ? 228 PHE B CB  1 
ATOM 5048 C CG  . PHE D 4 228 ? 336.566 350.332 450.480 1.00 99.01  ? 228 PHE B CG  1 
ATOM 5049 C CD1 . PHE D 4 228 ? 337.184 349.619 451.486 1.00 99.01  ? 228 PHE B CD1 1 
ATOM 5050 C CD2 . PHE D 4 228 ? 336.840 350.003 449.175 1.00 99.01  ? 228 PHE B CD2 1 
ATOM 5051 C CE1 . PHE D 4 228 ? 338.062 348.601 451.192 1.00 99.01  ? 228 PHE B CE1 1 
ATOM 5052 C CE2 . PHE D 4 228 ? 337.714 348.984 448.878 1.00 99.01  ? 228 PHE B CE2 1 
ATOM 5053 C CZ  . PHE D 4 228 ? 338.324 348.285 449.889 1.00 99.01  ? 228 PHE B CZ  1 
ATOM 5054 N N   . VAL D 4 229 ? 333.732 353.403 451.990 1.00 101.14 ? 229 VAL B N   1 
ATOM 5055 C CA  . VAL D 4 229 ? 333.232 354.697 452.432 1.00 101.14 ? 229 VAL B CA  1 
ATOM 5056 C C   . VAL D 4 229 ? 332.009 354.424 453.293 1.00 101.14 ? 229 VAL B C   1 
ATOM 5057 O O   . VAL D 4 229 ? 331.000 353.917 452.785 1.00 101.14 ? 229 VAL B O   1 
ATOM 5058 C CB  . VAL D 4 229 ? 332.917 355.613 451.244 1.00 101.14 ? 229 VAL B CB  1 
ATOM 5059 C CG1 . VAL D 4 229 ? 332.223 356.864 451.722 1.00 101.14 ? 229 VAL B CG1 1 
ATOM 5060 C CG2 . VAL D 4 229 ? 334.195 355.970 450.524 1.00 101.14 ? 229 VAL B CG2 1 
ATOM 5061 N N   . PRO D 4 230 ? 332.056 354.727 454.587 1.00 101.14 ? 230 PRO B N   1 
ATOM 5062 C CA  . PRO D 4 230 ? 331.003 354.277 455.497 1.00 101.14 ? 230 PRO B CA  1 
ATOM 5063 C C   . PRO D 4 230 ? 329.731 355.087 455.328 1.00 101.14 ? 230 PRO B C   1 
ATOM 5064 O O   . PRO D 4 230 ? 329.703 356.137 454.687 1.00 101.14 ? 230 PRO B O   1 
ATOM 5065 C CB  . PRO D 4 230 ? 331.622 354.499 456.873 1.00 101.14 ? 230 PRO B CB  1 
ATOM 5066 C CG  . PRO D 4 230 ? 332.486 355.679 456.670 1.00 101.14 ? 230 PRO B CG  1 
ATOM 5067 C CD  . PRO D 4 230 ? 333.065 355.536 455.286 1.00 101.14 ? 230 PRO B CD  1 
ATOM 5068 N N   . LEU D 4 231 ? 328.667 354.565 455.926 1.00 102.90 ? 231 LEU B N   1 
ATOM 5069 C CA  . LEU D 4 231 ? 327.336 355.123 455.747 1.00 102.90 ? 231 LEU B CA  1 
ATOM 5070 C C   . LEU D 4 231 ? 327.218 356.476 456.426 1.00 102.90 ? 231 LEU B C   1 
ATOM 5071 O O   . LEU D 4 231 ? 327.872 356.741 457.436 1.00 102.90 ? 231 LEU B O   1 
ATOM 5072 C CB  . LEU D 4 231 ? 326.293 354.170 456.316 1.00 102.90 ? 231 LEU B CB  1 
ATOM 5073 C CG  . LEU D 4 231 ? 324.867 354.317 455.813 1.00 102.90 ? 231 LEU B CG  1 
ATOM 5074 C CD1 . LEU D 4 231 ? 324.747 353.662 454.467 1.00 102.90 ? 231 LEU B CD1 1 
ATOM 5075 C CD2 . LEU D 4 231 ? 323.919 353.691 456.795 1.00 102.90 ? 231 LEU B CD2 1 
ATOM 5076 N N   . ASN D 4 232 ? 326.388 357.338 455.860 1.00 105.69 ? 232 ASN B N   1 
ATOM 5077 C CA  . ASN D 4 232 ? 326.104 358.622 456.470 1.00 105.69 ? 232 ASN B CA  1 
ATOM 5078 C C   . ASN D 4 232 ? 324.697 359.051 456.102 1.00 105.69 ? 232 ASN B C   1 
ATOM 5079 O O   . ASN D 4 232 ? 324.189 358.701 455.036 1.00 105.69 ? 232 ASN B O   1 
ATOM 5080 C CB  . ASN D 4 232 ? 327.109 359.682 456.036 1.00 105.69 ? 232 ASN B CB  1 
ATOM 5081 C CG  . ASN D 4 232 ? 327.507 360.588 457.168 1.00 105.69 ? 232 ASN B CG  1 
ATOM 5082 O OD1 . ASN D 4 232 ? 326.987 360.476 458.275 1.00 105.69 ? 232 ASN B OD1 1 
ATOM 5083 N ND2 . ASN D 4 232 ? 328.442 361.490 456.903 1.00 105.69 ? 232 ASN B ND2 1 
ATOM 5084 N N   . TYR D 4 233 ? 324.078 359.806 456.999 1.00 108.17 ? 233 TYR B N   1 
ATOM 5085 C CA  . TYR D 4 233 ? 322.729 360.306 456.812 1.00 108.17 ? 233 TYR B CA  1 
ATOM 5086 C C   . TYR D 4 233 ? 322.564 361.516 457.711 1.00 108.17 ? 233 TYR B C   1 
ATOM 5087 O O   . TYR D 4 233 ? 323.355 361.741 458.627 1.00 108.17 ? 233 TYR B O   1 
ATOM 5088 C CB  . TYR D 4 233 ? 321.685 359.237 457.142 1.00 108.17 ? 233 TYR B CB  1 
ATOM 5089 C CG  . TYR D 4 233 ? 322.019 358.413 458.363 1.00 108.17 ? 233 TYR B CG  1 
ATOM 5090 C CD1 . TYR D 4 233 ? 321.763 358.890 459.640 1.00 108.17 ? 233 TYR B CD1 1 
ATOM 5091 C CD2 . TYR D 4 233 ? 322.583 357.157 458.237 1.00 108.17 ? 233 TYR B CD2 1 
ATOM 5092 C CE1 . TYR D 4 233 ? 322.069 358.147 460.751 1.00 108.17 ? 233 TYR B CE1 1 
ATOM 5093 C CE2 . TYR D 4 233 ? 322.892 356.405 459.347 1.00 108.17 ? 233 TYR B CE2 1 
ATOM 5094 C CZ  . TYR D 4 233 ? 322.633 356.907 460.598 1.00 108.17 ? 233 TYR B CZ  1 
ATOM 5095 O OH  . TYR D 4 233 ? 322.938 356.159 461.706 1.00 108.17 ? 233 TYR B OH  1 
ATOM 5096 N N   . SER D 4 234 ? 321.519 362.287 457.463 1.00 117.62 ? 234 SER B N   1 
ATOM 5097 C CA  . SER D 4 234 ? 321.221 363.370 458.380 1.00 117.62 ? 234 SER B CA  1 
ATOM 5098 C C   . SER D 4 234 ? 320.342 362.865 459.514 1.00 117.62 ? 234 SER B C   1 
ATOM 5099 O O   . SER D 4 234 ? 319.919 361.710 459.542 1.00 117.62 ? 234 SER B O   1 
ATOM 5100 C CB  . SER D 4 234 ? 320.542 364.523 457.658 1.00 117.62 ? 234 SER B CB  1 
ATOM 5101 O OG  . SER D 4 234 ? 320.144 365.521 458.579 1.00 117.62 ? 234 SER B OG  1 
ATOM 5102 N N   . GLU D 4 235 ? 320.066 363.752 460.459 1.00 122.34 ? 235 GLU B N   1 
ATOM 5103 C CA  . GLU D 4 235 ? 319.236 363.391 461.598 1.00 122.34 ? 235 GLU B CA  1 
ATOM 5104 C C   . GLU D 4 235 ? 317.777 363.339 461.173 1.00 122.34 ? 235 GLU B C   1 
ATOM 5105 O O   . GLU D 4 235 ? 317.202 364.354 460.770 1.00 122.34 ? 235 GLU B O   1 
ATOM 5106 C CB  . GLU D 4 235 ? 319.429 364.394 462.729 1.00 122.34 ? 235 GLU B CB  1 
ATOM 5107 C CG  . GLU D 4 235 ? 318.499 364.223 463.927 1.00 122.34 ? 235 GLU B CG  1 
ATOM 5108 C CD  . GLU D 4 235 ? 318.429 362.797 464.449 1.00 122.34 ? 235 GLU B CD  1 
ATOM 5109 O OE1 . GLU D 4 235 ? 319.225 362.464 465.351 1.00 122.34 ? 235 GLU B OE1 1 
ATOM 5110 O OE2 . GLU D 4 235 ? 317.548 362.026 464.010 1.00 122.34 ? 235 GLU B OE2 1 
ATOM 5111 N N   . GLY D 4 236 ? 317.178 362.159 461.263 1.00 115.61 ? 236 GLY B N   1 
ATOM 5112 C CA  . GLY D 4 236 ? 315.794 361.995 460.877 1.00 115.61 ? 236 GLY B CA  1 
ATOM 5113 C C   . GLY D 4 236 ? 315.582 360.797 459.981 1.00 115.61 ? 236 GLY B C   1 
ATOM 5114 O O   . GLY D 4 236 ? 314.523 360.168 460.017 1.00 115.61 ? 236 GLY B O   1 
ATOM 5115 N N   . SER D 4 237 ? 316.586 360.470 459.174 1.00 111.24 ? 237 SER B N   1 
ATOM 5116 C CA  . SER D 4 237 ? 316.501 359.330 458.279 1.00 111.24 ? 237 SER B CA  1 
ATOM 5117 C C   . SER D 4 237 ? 316.629 358.032 459.070 1.00 111.24 ? 237 SER B C   1 
ATOM 5118 O O   . SER D 4 237 ? 316.993 358.023 460.247 1.00 111.24 ? 237 SER B O   1 
ATOM 5119 C CB  . SER D 4 237 ? 317.571 359.427 457.199 1.00 111.24 ? 237 SER B CB  1 
ATOM 5120 O OG  . SER D 4 237 ? 317.363 360.567 456.390 1.00 111.24 ? 237 SER B OG  1 
ATOM 5121 N N   . SER D 4 238 ? 316.315 356.923 458.419 1.00 105.77 ? 238 SER B N   1 
ATOM 5122 C CA  . SER D 4 238 ? 316.409 355.627 459.074 1.00 105.77 ? 238 SER B CA  1 
ATOM 5123 C C   . SER D 4 238 ? 317.874 355.251 459.245 1.00 105.77 ? 238 SER B C   1 
ATOM 5124 O O   . SER D 4 238 ? 318.629 355.271 458.270 1.00 105.77 ? 238 SER B O   1 
ATOM 5125 C CB  . SER D 4 238 ? 315.680 354.567 458.263 1.00 105.77 ? 238 SER B CB  1 
ATOM 5126 O OG  . SER D 4 238 ? 316.233 354.460 456.966 1.00 105.77 ? 238 SER B OG  1 
ATOM 5127 N N   . PRO D 4 239 ? 318.309 354.899 460.449 1.00 104.21 ? 239 PRO B N   1 
ATOM 5128 C CA  . PRO D 4 239 ? 319.749 354.768 460.708 1.00 104.21 ? 239 PRO B CA  1 
ATOM 5129 C C   . PRO D 4 239 ? 320.378 353.451 460.279 1.00 104.21 ? 239 PRO B C   1 
ATOM 5130 O O   . PRO D 4 239 ? 321.484 353.138 460.723 1.00 104.21 ? 239 PRO B O   1 
ATOM 5131 C CB  . PRO D 4 239 ? 319.834 354.939 462.227 1.00 104.21 ? 239 PRO B CB  1 
ATOM 5132 C CG  . PRO D 4 239 ? 318.535 354.441 462.718 1.00 104.21 ? 239 PRO B CG  1 
ATOM 5133 C CD  . PRO D 4 239 ? 317.518 354.817 461.686 1.00 104.21 ? 239 PRO B CD  1 
ATOM 5134 N N   . TYR D 4 240 ? 319.710 352.669 459.436 1.00 102.31 ? 240 TYR B N   1 
ATOM 5135 C CA  . TYR D 4 240 ? 320.265 351.407 458.976 1.00 102.31 ? 240 TYR B CA  1 
ATOM 5136 C C   . TYR D 4 240 ? 319.827 351.146 457.546 1.00 102.31 ? 240 TYR B C   1 
ATOM 5137 O O   . TYR D 4 240 ? 318.743 351.545 457.124 1.00 102.31 ? 240 TYR B O   1 
ATOM 5138 C CB  . TYR D 4 240 ? 319.840 350.240 459.872 1.00 102.31 ? 240 TYR B CB  1 
ATOM 5139 C CG  . TYR D 4 240 ? 318.415 350.326 460.353 1.00 102.31 ? 240 TYR B CG  1 
ATOM 5140 C CD1 . TYR D 4 240 ? 317.362 349.934 459.539 1.00 102.31 ? 240 TYR B CD1 1 
ATOM 5141 C CD2 . TYR D 4 240 ? 318.122 350.793 461.626 1.00 102.31 ? 240 TYR B CD2 1 
ATOM 5142 C CE1 . TYR D 4 240 ? 316.059 350.012 459.971 1.00 102.31 ? 240 TYR B CE1 1 
ATOM 5143 C CE2 . TYR D 4 240 ? 316.819 350.875 462.070 1.00 102.31 ? 240 TYR B CE2 1 
ATOM 5144 C CZ  . TYR D 4 240 ? 315.792 350.483 461.237 1.00 102.31 ? 240 TYR B CZ  1 
ATOM 5145 O OH  . TYR D 4 240 ? 314.492 350.561 461.675 1.00 102.31 ? 240 TYR B OH  1 
ATOM 5146 N N   . VAL D 4 241 ? 320.691 350.463 456.797 1.00 99.30  ? 241 VAL B N   1 
ATOM 5147 C CA  . VAL D 4 241 ? 320.388 350.023 455.445 1.00 99.30  ? 241 VAL B CA  1 
ATOM 5148 C C   . VAL D 4 241 ? 320.529 348.508 455.395 1.00 99.30  ? 241 VAL B C   1 
ATOM 5149 O O   . VAL D 4 241 ? 321.644 347.992 455.487 1.00 99.30  ? 241 VAL B O   1 
ATOM 5150 C CB  . VAL D 4 241 ? 321.302 350.669 454.392 1.00 99.30  ? 241 VAL B CB  1 
ATOM 5151 C CG1 . VAL D 4 241 ? 320.823 350.304 453.015 1.00 99.30  ? 241 VAL B CG1 1 
ATOM 5152 C CG2 . VAL D 4 241 ? 321.316 352.168 454.551 1.00 99.30  ? 241 VAL B CG2 1 
ATOM 5153 N N   . PRO D 4 242 ? 319.447 347.753 455.242 1.00 99.32  ? 242 PRO B N   1 
ATOM 5154 C CA  . PRO D 4 242 ? 319.563 346.294 455.257 1.00 99.32  ? 242 PRO B CA  1 
ATOM 5155 C C   . PRO D 4 242 ? 320.088 345.753 453.939 1.00 99.32  ? 242 PRO B C   1 
ATOM 5156 O O   . PRO D 4 242 ? 319.775 346.265 452.864 1.00 99.32  ? 242 PRO B O   1 
ATOM 5157 C CB  . PRO D 4 242 ? 318.126 345.835 455.513 1.00 99.32  ? 242 PRO B CB  1 
ATOM 5158 C CG  . PRO D 4 242 ? 317.294 346.918 454.953 1.00 99.32  ? 242 PRO B CG  1 
ATOM 5159 C CD  . PRO D 4 242 ? 318.048 348.196 455.144 1.00 99.32  ? 242 PRO B CD  1 
ATOM 5160 N N   . ILE D 4 243 ? 320.899 344.704 454.035 1.00 97.62  ? 243 ILE B N   1 
ATOM 5161 C CA  . ILE D 4 243 ? 321.485 344.031 452.881 1.00 97.62  ? 243 ILE B CA  1 
ATOM 5162 C C   . ILE D 4 243 ? 320.874 342.643 452.794 1.00 97.62  ? 243 ILE B C   1 
ATOM 5163 O O   . ILE D 4 243 ? 320.689 341.981 453.819 1.00 97.62  ? 243 ILE B O   1 
ATOM 5164 C CB  . ILE D 4 243 ? 323.018 343.948 452.991 1.00 97.62  ? 243 ILE B CB  1 
ATOM 5165 C CG1 . ILE D 4 243 ? 323.589 345.279 453.460 1.00 97.62  ? 243 ILE B CG1 1 
ATOM 5166 C CG2 . ILE D 4 243 ? 323.631 343.600 451.660 1.00 97.62  ? 243 ILE B CG2 1 
ATOM 5167 C CD1 . ILE D 4 243 ? 325.073 345.266 453.640 1.00 97.62  ? 243 ILE B CD1 1 
ATOM 5168 N N   . THR D 4 244 ? 320.558 342.203 451.582 1.00 95.19  ? 244 THR B N   1 
ATOM 5169 C CA  . THR D 4 244 ? 319.916 340.915 451.363 1.00 95.19  ? 244 THR B CA  1 
ATOM 5170 C C   . THR D 4 244 ? 320.739 340.115 450.369 1.00 95.19  ? 244 THR B C   1 
ATOM 5171 O O   . THR D 4 244 ? 320.968 340.569 449.246 1.00 95.19  ? 244 THR B O   1 
ATOM 5172 C CB  . THR D 4 244 ? 318.490 341.104 450.853 1.00 95.19  ? 244 THR B CB  1 
ATOM 5173 O OG1 . THR D 4 244 ? 317.689 341.674 451.892 1.00 95.19  ? 244 THR B OG1 1 
ATOM 5174 C CG2 . THR D 4 244 ? 317.892 339.780 450.434 1.00 95.19  ? 244 THR B CG2 1 
ATOM 5175 N N   . VAL D 4 245 ? 321.172 338.927 450.777 1.00 93.76  ? 245 VAL B N   1 
ATOM 5176 C CA  . VAL D 4 245 ? 322.006 338.059 449.956 1.00 93.76  ? 245 VAL B CA  1 
ATOM 5177 C C   . VAL D 4 245 ? 321.182 336.853 449.540 1.00 93.76  ? 245 VAL B C   1 
ATOM 5178 O O   . VAL D 4 245 ? 320.651 336.135 450.394 1.00 93.76  ? 245 VAL B O   1 
ATOM 5179 C CB  . VAL D 4 245 ? 323.268 337.623 450.714 1.00 93.76  ? 245 VAL B CB  1 
ATOM 5180 C CG1 . VAL D 4 245 ? 324.021 336.581 449.927 1.00 93.76  ? 245 VAL B CG1 1 
ATOM 5181 C CG2 . VAL D 4 245 ? 324.147 338.815 450.978 1.00 93.76  ? 245 VAL B CG2 1 
ATOM 5182 N N   . THR D 4 246 ? 321.085 336.620 448.234 1.00 99.06  ? 246 THR B N   1 
ATOM 5183 C CA  . THR D 4 246 ? 320.277 335.538 447.686 1.00 99.06  ? 246 THR B CA  1 
ATOM 5184 C C   . THR D 4 246 ? 321.152 334.661 446.808 1.00 99.06  ? 246 THR B C   1 
ATOM 5185 O O   . THR D 4 246 ? 321.665 335.123 445.786 1.00 99.06  ? 246 THR B O   1 
ATOM 5186 C CB  . THR D 4 246 ? 319.104 336.090 446.880 1.00 99.06  ? 246 THR B CB  1 
ATOM 5187 O OG1 . THR D 4 246 ? 318.304 336.931 447.715 1.00 99.06  ? 246 THR B OG1 1 
ATOM 5188 C CG2 . THR D 4 246 ? 318.258 334.966 446.372 1.00 99.06  ? 246 THR B CG2 1 
ATOM 5189 N N   . ILE D 4 247 ? 321.310 333.400 447.192 1.00 99.46  ? 247 ILE B N   1 
ATOM 5190 C CA  . ILE D 4 247 ? 322.203 332.466 446.518 1.00 99.46  ? 247 ILE B CA  1 
ATOM 5191 C C   . ILE D 4 247 ? 321.370 331.381 445.854 1.00 99.46  ? 247 ILE B C   1 
ATOM 5192 O O   . ILE D 4 247 ? 320.375 330.920 446.421 1.00 99.46  ? 247 ILE B O   1 
ATOM 5193 C CB  . ILE D 4 247 ? 323.204 331.857 447.516 1.00 99.46  ? 247 ILE B CB  1 
ATOM 5194 C CG1 . ILE D 4 247 ? 323.773 332.945 448.419 1.00 99.46  ? 247 ILE B CG1 1 
ATOM 5195 C CG2 . ILE D 4 247 ? 324.330 331.162 446.797 1.00 99.46  ? 247 ILE B CG2 1 
ATOM 5196 C CD1 . ILE D 4 247 ? 324.244 332.435 449.745 1.00 99.46  ? 247 ILE B CD1 1 
ATOM 5197 N N   . ALA D 4 248 ? 321.771 330.975 444.657 1.00 105.51 ? 248 ALA B N   1 
ATOM 5198 C CA  . ALA D 4 248 ? 321.091 329.894 443.959 1.00 105.51 ? 248 ALA B CA  1 
ATOM 5199 C C   . ALA D 4 248 ? 322.108 328.992 443.275 1.00 105.51 ? 248 ALA B C   1 
ATOM 5200 O O   . ALA D 4 248 ? 322.881 329.464 442.435 1.00 105.51 ? 248 ALA B O   1 
ATOM 5201 C CB  . ALA D 4 248 ? 320.106 330.451 442.936 1.00 105.51 ? 248 ALA B CB  1 
ATOM 5202 N N   . PRO D 4 249 ? 322.141 327.702 443.596 1.00 109.49 ? 249 PRO B N   1 
ATOM 5203 C CA  . PRO D 4 249 ? 323.160 326.824 443.018 1.00 109.49 ? 249 PRO B CA  1 
ATOM 5204 C C   . PRO D 4 249 ? 322.859 326.472 441.573 1.00 109.49 ? 249 PRO B C   1 
ATOM 5205 O O   . PRO D 4 249 ? 321.722 326.171 441.206 1.00 109.49 ? 249 PRO B O   1 
ATOM 5206 C CB  . PRO D 4 249 ? 323.102 325.578 443.906 1.00 109.49 ? 249 PRO B CB  1 
ATOM 5207 C CG  . PRO D 4 249 ? 322.280 325.964 445.082 1.00 109.49 ? 249 PRO B CG  1 
ATOM 5208 C CD  . PRO D 4 249 ? 321.341 327.003 444.606 1.00 109.49 ? 249 PRO B CD  1 
ATOM 5209 N N   . MET D 4 250 ? 323.905 326.496 440.749 1.00 117.28 ? 250 MET B N   1 
ATOM 5210 C CA  . MET D 4 250 ? 323.784 326.191 439.331 1.00 117.28 ? 250 MET B CA  1 
ATOM 5211 C C   . MET D 4 250 ? 324.652 324.994 438.985 1.00 117.28 ? 250 MET B C   1 
ATOM 5212 O O   . MET D 4 250 ? 325.823 324.955 439.369 1.00 117.28 ? 250 MET B O   1 
ATOM 5213 C CB  . MET D 4 250 ? 324.195 327.383 438.460 1.00 117.28 ? 250 MET B CB  1 
ATOM 5214 C CG  . MET D 4 250 ? 323.260 328.574 438.520 1.00 117.28 ? 250 MET B CG  1 
ATOM 5215 S SD  . MET D 4 250 ? 321.506 328.160 438.561 1.00 117.28 ? 250 MET B SD  1 
ATOM 5216 C CE  . MET D 4 250 ? 321.233 327.484 436.923 1.00 117.28 ? 250 MET B CE  1 
ATOM 5217 N N   . CYS D 4 251 ? 324.063 324.035 438.261 1.00 126.54 ? 251 CYS B N   1 
ATOM 5218 C CA  . CYS D 4 251 ? 324.753 322.876 437.682 1.00 126.54 ? 251 CYS B CA  1 
ATOM 5219 C C   . CYS D 4 251 ? 325.426 322.011 438.747 1.00 126.54 ? 251 CYS B C   1 
ATOM 5220 O O   . CYS D 4 251 ? 326.637 321.791 438.728 1.00 126.54 ? 251 CYS B O   1 
ATOM 5221 C CB  . CYS D 4 251 ? 325.757 323.308 436.612 1.00 126.54 ? 251 CYS B CB  1 
ATOM 5222 S SG  . CYS D 4 251 ? 325.011 324.166 435.213 1.00 126.54 ? 251 CYS B SG  1 
ATOM 5223 N N   . ALA D 4 252 ? 324.619 321.511 439.677 1.00 128.44 ? 252 ALA B N   1 
ATOM 5224 C CA  . ALA D 4 252 ? 325.099 320.656 440.749 1.00 128.44 ? 252 ALA B CA  1 
ATOM 5225 C C   . ALA D 4 252 ? 324.997 319.191 440.353 1.00 128.44 ? 252 ALA B C   1 
ATOM 5226 O O   . ALA D 4 252 ? 324.019 318.766 439.736 1.00 128.44 ? 252 ALA B O   1 
ATOM 5227 C CB  . ALA D 4 252 ? 324.299 320.897 442.026 1.00 128.44 ? 252 ALA B CB  1 
ATOM 5228 N N   . GLU D 4 253 ? 326.016 318.418 440.719 1.00 130.00 ? 253 GLU B N   1 
ATOM 5229 C CA  . GLU D 4 253 ? 325.996 316.981 440.485 1.00 130.00 ? 253 GLU B CA  1 
ATOM 5230 C C   . GLU D 4 253 ? 326.818 316.292 441.561 1.00 130.00 ? 253 GLU B C   1 
ATOM 5231 O O   . GLU D 4 253 ? 327.860 316.790 441.989 1.00 130.00 ? 253 GLU B O   1 
ATOM 5232 C CB  . GLU D 4 253 ? 326.500 316.626 439.084 1.00 130.00 ? 253 GLU B CB  1 
ATOM 5233 C CG  . GLU D 4 253 ? 327.894 317.095 438.756 1.00 130.00 ? 253 GLU B CG  1 
ATOM 5234 C CD  . GLU D 4 253 ? 328.250 316.845 437.307 1.00 130.00 ? 253 GLU B CD  1 
ATOM 5235 O OE1 . GLU D 4 253 ? 327.388 316.329 436.568 1.00 130.00 ? 253 GLU B OE1 1 
ATOM 5236 O OE2 . GLU D 4 253 ? 329.386 317.163 436.903 1.00 130.00 ? 253 GLU B OE2 1 
ATOM 5237 N N   . TYR D 4 254 ? 326.323 315.139 442.001 1.00 131.17 ? 254 TYR B N   1 
ATOM 5238 C CA  . TYR D 4 254 ? 326.864 314.429 443.149 1.00 131.17 ? 254 TYR B CA  1 
ATOM 5239 C C   . TYR D 4 254 ? 327.354 313.055 442.717 1.00 131.17 ? 254 TYR B C   1 
ATOM 5240 O O   . TYR D 4 254 ? 327.399 312.733 441.532 1.00 131.17 ? 254 TYR B O   1 
ATOM 5241 C CB  . TYR D 4 254 ? 325.821 314.294 444.261 1.00 131.17 ? 254 TYR B CB  1 
ATOM 5242 C CG  . TYR D 4 254 ? 325.232 315.597 444.727 1.00 131.17 ? 254 TYR B CG  1 
ATOM 5243 C CD1 . TYR D 4 254 ? 325.824 316.320 445.749 1.00 131.17 ? 254 TYR B CD1 1 
ATOM 5244 C CD2 . TYR D 4 254 ? 324.074 316.093 444.160 1.00 131.17 ? 254 TYR B CD2 1 
ATOM 5245 C CE1 . TYR D 4 254 ? 325.283 317.508 446.182 1.00 131.17 ? 254 TYR B CE1 1 
ATOM 5246 C CE2 . TYR D 4 254 ? 323.527 317.277 444.585 1.00 131.17 ? 254 TYR B CE2 1 
ATOM 5247 C CZ  . TYR D 4 254 ? 324.134 317.979 445.595 1.00 131.17 ? 254 TYR B CZ  1 
ATOM 5248 O OH  . TYR D 4 254 ? 323.584 319.163 446.019 1.00 131.17 ? 254 TYR B OH  1 
ATOM 5249 N N   . ASN D 4 255 ? 327.716 312.236 443.699 1.00 139.49 ? 255 ASN B N   1 
ATOM 5250 C CA  . ASN D 4 255 ? 328.335 310.939 443.464 1.00 139.49 ? 255 ASN B CA  1 
ATOM 5251 C C   . ASN D 4 255 ? 327.681 309.928 444.393 1.00 139.49 ? 255 ASN B C   1 
ATOM 5252 O O   . ASN D 4 255 ? 327.921 309.950 445.605 1.00 139.49 ? 255 ASN B O   1 
ATOM 5253 C CB  . ASN D 4 255 ? 329.851 311.039 443.688 1.00 139.49 ? 255 ASN B CB  1 
ATOM 5254 C CG  . ASN D 4 255 ? 330.599 309.719 443.479 1.00 139.49 ? 255 ASN B CG  1 
ATOM 5255 O OD1 . ASN D 4 255 ? 330.413 308.740 444.203 1.00 139.49 ? 255 ASN B OD1 1 
ATOM 5256 N ND2 . ASN D 4 255 ? 331.466 309.700 442.472 1.00 139.49 ? 255 ASN B ND2 1 
ATOM 5257 N N   . GLY D 4 256 ? 326.879 309.036 443.826 1.00 145.91 ? 256 GLY B N   1 
ATOM 5258 C CA  . GLY D 4 256 ? 326.236 308.001 444.616 1.00 145.91 ? 256 GLY B CA  1 
ATOM 5259 C C   . GLY D 4 256 ? 325.460 307.058 443.722 1.00 145.91 ? 256 GLY B C   1 
ATOM 5260 O O   . GLY D 4 256 ? 325.277 307.308 442.526 1.00 145.91 ? 256 GLY B O   1 
ATOM 5261 N N   . LEU D 4 257 ? 325.015 305.959 444.327 1.00 147.99 ? 257 LEU B N   1 
ATOM 5262 C CA  . LEU D 4 257 ? 324.173 304.996 443.623 1.00 147.99 ? 257 LEU B CA  1 
ATOM 5263 C C   . LEU D 4 257 ? 322.727 305.161 444.079 1.00 147.99 ? 257 LEU B C   1 
ATOM 5264 O O   . LEU D 4 257 ? 321.793 304.925 443.310 1.00 147.99 ? 257 LEU B O   1 
ATOM 5265 C CB  . LEU D 4 257 ? 324.655 303.557 443.857 1.00 147.99 ? 257 LEU B CB  1 
ATOM 5266 C CG  . LEU D 4 257 ? 324.207 302.480 442.854 1.00 147.99 ? 257 LEU B CG  1 
ATOM 5267 C CD1 . LEU D 4 257 ? 325.304 301.449 442.642 1.00 147.99 ? 257 LEU B CD1 1 
ATOM 5268 C CD2 . LEU D 4 257 ? 322.928 301.776 443.277 1.00 147.99 ? 257 LEU B CD2 1 
ATOM 5269 N N   . GLY E 5 1   ? 387.699 305.915 418.844 1.00 131.79 ? 1   GLY C N   1 
ATOM 5270 C CA  . GLY E 5 1   ? 386.440 306.114 418.148 1.00 131.79 ? 1   GLY C CA  1 
ATOM 5271 C C   . GLY E 5 1   ? 386.255 307.537 417.667 1.00 131.79 ? 1   GLY C C   1 
ATOM 5272 O O   . GLY E 5 1   ? 387.105 308.078 416.967 1.00 131.79 ? 1   GLY C O   1 
ATOM 5273 N N   . LEU E 5 2   ? 385.138 308.143 418.040 1.00 125.95 ? 2   LEU C N   1 
ATOM 5274 C CA  . LEU E 5 2   ? 384.902 309.528 417.683 1.00 125.95 ? 2   LEU C CA  1 
ATOM 5275 C C   . LEU E 5 2   ? 385.754 310.440 418.560 1.00 125.95 ? 2   LEU C C   1 
ATOM 5276 O O   . LEU E 5 2   ? 385.644 310.400 419.787 1.00 125.95 ? 2   LEU C O   1 
ATOM 5277 C CB  . LEU E 5 2   ? 383.427 309.873 417.847 1.00 125.95 ? 2   LEU C CB  1 
ATOM 5278 C CG  . LEU E 5 2   ? 383.044 311.315 417.538 1.00 125.95 ? 2   LEU C CG  1 
ATOM 5279 C CD1 . LEU E 5 2   ? 383.198 311.600 416.061 1.00 125.95 ? 2   LEU C CD1 1 
ATOM 5280 C CD2 . LEU E 5 2   ? 381.625 311.584 417.988 1.00 125.95 ? 2   LEU C CD2 1 
ATOM 5281 N N   . PRO E 5 3   ? 386.618 311.266 417.968 1.00 120.95 ? 3   PRO C N   1 
ATOM 5282 C CA  . PRO E 5 3   ? 387.508 312.115 418.771 1.00 120.95 ? 3   PRO C CA  1 
ATOM 5283 C C   . PRO E 5 3   ? 386.809 313.405 419.168 1.00 120.95 ? 3   PRO C C   1 
ATOM 5284 O O   . PRO E 5 3   ? 386.335 314.153 418.312 1.00 120.95 ? 3   PRO C O   1 
ATOM 5285 C CB  . PRO E 5 3   ? 388.686 312.384 417.826 1.00 120.95 ? 3   PRO C CB  1 
ATOM 5286 C CG  . PRO E 5 3   ? 388.407 311.583 416.576 1.00 120.95 ? 3   PRO C CG  1 
ATOM 5287 C CD  . PRO E 5 3   ? 386.941 311.356 416.542 1.00 120.95 ? 3   PRO C CD  1 
ATOM 5288 N N   . VAL E 5 4   ? 386.758 313.674 420.469 1.00 116.36 ? 4   VAL C N   1 
ATOM 5289 C CA  . VAL E 5 4   ? 386.168 314.895 420.990 1.00 116.36 ? 4   VAL C CA  1 
ATOM 5290 C C   . VAL E 5 4   ? 387.271 315.734 421.620 1.00 116.36 ? 4   VAL C C   1 
ATOM 5291 O O   . VAL E 5 4   ? 388.421 315.314 421.721 1.00 116.36 ? 4   VAL C O   1 
ATOM 5292 C CB  . VAL E 5 4   ? 385.049 314.618 422.005 1.00 116.36 ? 4   VAL C CB  1 
ATOM 5293 C CG1 . VAL E 5 4   ? 384.011 313.707 421.400 1.00 116.36 ? 4   VAL C CG1 1 
ATOM 5294 C CG2 . VAL E 5 4   ? 385.623 314.008 423.257 1.00 116.36 ? 4   VAL C CG2 1 
ATOM 5295 N N   . MET E 5 5   ? 386.901 316.939 422.043 1.00 114.29 ? 5   MET C N   1 
ATOM 5296 C CA  . MET E 5 5   ? 387.843 317.872 422.647 1.00 114.29 ? 5   MET C CA  1 
ATOM 5297 C C   . MET E 5 5   ? 387.047 318.866 423.472 1.00 114.29 ? 5   MET C C   1 
ATOM 5298 O O   . MET E 5 5   ? 386.322 319.688 422.910 1.00 114.29 ? 5   MET C O   1 
ATOM 5299 C CB  . MET E 5 5   ? 388.655 318.587 421.571 1.00 114.29 ? 5   MET C CB  1 
ATOM 5300 C CG  . MET E 5 5   ? 389.589 319.652 422.083 1.00 114.29 ? 5   MET C CG  1 
ATOM 5301 S SD  . MET E 5 5   ? 390.119 320.763 420.768 1.00 114.29 ? 5   MET C SD  1 
ATOM 5302 C CE  . MET E 5 5   ? 390.380 319.613 419.419 1.00 114.29 ? 5   MET C CE  1 
ATOM 5303 N N   . THR E 5 6   ? 387.179 318.798 424.792 1.00 107.77 ? 6   THR C N   1 
ATOM 5304 C CA  . THR E 5 6   ? 386.337 319.594 425.672 1.00 107.77 ? 6   THR C CA  1 
ATOM 5305 C C   . THR E 5 6   ? 386.811 321.040 425.715 1.00 107.77 ? 6   THR C C   1 
ATOM 5306 O O   . THR E 5 6   ? 388.009 321.310 425.826 1.00 107.77 ? 6   THR C O   1 
ATOM 5307 C CB  . THR E 5 6   ? 386.329 319.005 427.078 1.00 107.77 ? 6   THR C CB  1 
ATOM 5308 O OG1 . THR E 5 6   ? 387.675 318.784 427.507 1.00 107.77 ? 6   THR C OG1 1 
ATOM 5309 C CG2 . THR E 5 6   ? 385.592 317.689 427.093 1.00 107.77 ? 6   THR C CG2 1 
ATOM 5310 N N   . THR E 5 7   ? 385.869 321.963 425.624 1.00 107.31 ? 7   THR C N   1 
ATOM 5311 C CA  . THR E 5 7   ? 386.142 323.381 425.743 1.00 107.31 ? 7   THR C CA  1 
ATOM 5312 C C   . THR E 5 7   ? 386.176 323.781 427.214 1.00 107.31 ? 7   THR C C   1 
ATOM 5313 O O   . THR E 5 7   ? 385.773 323.000 428.077 1.00 107.31 ? 7   THR C O   1 
ATOM 5314 C CB  . THR E 5 7   ? 385.068 324.169 425.001 1.00 107.31 ? 7   THR C CB  1 
ATOM 5315 O OG1 . THR E 5 7   ? 383.790 323.885 425.577 1.00 107.31 ? 7   THR C OG1 1 
ATOM 5316 C CG2 . THR E 5 7   ? 385.051 323.789 423.538 1.00 107.31 ? 7   THR C CG2 1 
ATOM 5317 N N   . PRO E 5 8   ? 386.687 324.972 427.536 1.00 104.69 ? 8   PRO C N   1 
ATOM 5318 C CA  . PRO E 5 8   ? 386.497 325.500 428.889 1.00 104.69 ? 8   PRO C CA  1 
ATOM 5319 C C   . PRO E 5 8   ? 385.033 325.742 429.211 1.00 104.69 ? 8   PRO C C   1 
ATOM 5320 O O   . PRO E 5 8   ? 384.200 325.964 428.330 1.00 104.69 ? 8   PRO C O   1 
ATOM 5321 C CB  . PRO E 5 8   ? 387.284 326.816 428.876 1.00 104.69 ? 8   PRO C CB  1 
ATOM 5322 C CG  . PRO E 5 8   ? 387.656 327.049 427.464 1.00 104.69 ? 8   PRO C CG  1 
ATOM 5323 C CD  . PRO E 5 8   ? 387.761 325.704 426.852 1.00 104.69 ? 8   PRO C CD  1 
ATOM 5324 N N   . GLY E 5 9   ? 384.728 325.694 430.501 1.00 104.73 ? 9   GLY C N   1 
ATOM 5325 C CA  . GLY E 5 9   ? 383.351 325.721 430.935 1.00 104.73 ? 9   GLY C CA  1 
ATOM 5326 C C   . GLY E 5 9   ? 382.650 324.397 430.780 1.00 104.73 ? 9   GLY C C   1 
ATOM 5327 O O   . GLY E 5 9   ? 381.516 324.360 430.297 1.00 104.73 ? 9   GLY C O   1 
ATOM 5328 N N   . SER E 5 10  ? 383.298 323.298 431.159 1.00 104.80 ? 10  SER C N   1 
ATOM 5329 C CA  . SER E 5 10  ? 382.712 321.983 430.938 1.00 104.80 ? 10  SER C CA  1 
ATOM 5330 C C   . SER E 5 10  ? 381.966 321.473 432.166 1.00 104.80 ? 10  SER C C   1 
ATOM 5331 O O   . SER E 5 10  ? 380.746 321.300 432.131 1.00 104.80 ? 10  SER C O   1 
ATOM 5332 C CB  . SER E 5 10  ? 383.802 320.990 430.532 1.00 104.80 ? 10  SER C CB  1 
ATOM 5333 O OG  . SER E 5 10  ? 384.356 320.382 431.679 1.00 104.80 ? 10  SER C OG  1 
ATOM 5334 N N   . THR E 5 11  ? 382.679 321.239 433.259 1.00 104.91 ? 11  THR C N   1 
ATOM 5335 C CA  . THR E 5 11  ? 382.050 320.684 434.455 1.00 104.91 ? 11  THR C CA  1 
ATOM 5336 C C   . THR E 5 11  ? 381.674 321.773 435.452 1.00 104.91 ? 11  THR C C   1 
ATOM 5337 O O   . THR E 5 11  ? 382.113 321.768 436.598 1.00 104.91 ? 11  THR C O   1 
ATOM 5338 C CB  . THR E 5 11  ? 382.969 319.655 435.094 1.00 104.91 ? 11  THR C CB  1 
ATOM 5339 O OG1 . THR E 5 11  ? 384.277 320.216 435.252 1.00 104.91 ? 11  THR C OG1 1 
ATOM 5340 C CG2 . THR E 5 11  ? 383.059 318.422 434.219 1.00 104.91 ? 11  THR C CG2 1 
ATOM 5341 N N   . GLN E 5 12  ? 380.852 322.719 435.020 1.00 98.60  ? 12  GLN C N   1 
ATOM 5342 C CA  . GLN E 5 12  ? 380.449 323.829 435.862 1.00 98.60  ? 12  GLN C CA  1 
ATOM 5343 C C   . GLN E 5 12  ? 378.937 323.850 435.998 1.00 98.60  ? 12  GLN C C   1 
ATOM 5344 O O   . GLN E 5 12  ? 378.205 323.329 435.155 1.00 98.60  ? 12  GLN C O   1 
ATOM 5345 C CB  . GLN E 5 12  ? 380.938 325.160 435.300 1.00 98.60  ? 12  GLN C CB  1 
ATOM 5346 C CG  . GLN E 5 12  ? 380.386 325.483 433.942 1.00 98.60  ? 12  GLN C CG  1 
ATOM 5347 C CD  . GLN E 5 12  ? 380.575 326.929 433.586 1.00 98.60  ? 12  GLN C CD  1 
ATOM 5348 O OE1 . GLN E 5 12  ? 381.455 327.594 434.120 1.00 98.60  ? 12  GLN C OE1 1 
ATOM 5349 N NE2 . GLN E 5 12  ? 379.748 327.432 432.683 1.00 98.60  ? 12  GLN C NE2 1 
ATOM 5350 N N   . PHE E 5 13  ? 378.477 324.465 437.072 1.00 97.03  ? 13  PHE C N   1 
ATOM 5351 C CA  . PHE E 5 13  ? 377.059 324.562 437.385 1.00 97.03  ? 13  PHE C CA  1 
ATOM 5352 C C   . PHE E 5 13  ? 376.686 326.035 437.308 1.00 97.03  ? 13  PHE C C   1 
ATOM 5353 O O   . PHE E 5 13  ? 376.728 326.752 438.309 1.00 97.03  ? 13  PHE C O   1 
ATOM 5354 C CB  . PHE E 5 13  ? 376.773 323.961 438.758 1.00 97.03  ? 13  PHE C CB  1 
ATOM 5355 C CG  . PHE E 5 13  ? 375.362 324.146 439.239 1.00 97.03  ? 13  PHE C CG  1 
ATOM 5356 C CD1 . PHE E 5 13  ? 374.285 323.971 438.389 1.00 97.03  ? 13  PHE C CD1 1 
ATOM 5357 C CD2 . PHE E 5 13  ? 375.118 324.478 440.554 1.00 97.03  ? 13  PHE C CD2 1 
ATOM 5358 C CE1 . PHE E 5 13  ? 372.998 324.146 438.841 1.00 97.03  ? 13  PHE C CE1 1 
ATOM 5359 C CE2 . PHE E 5 13  ? 373.836 324.647 441.009 1.00 97.03  ? 13  PHE C CE2 1 
ATOM 5360 C CZ  . PHE E 5 13  ? 372.777 324.483 440.151 1.00 97.03  ? 13  PHE C CZ  1 
ATOM 5361 N N   . LEU E 5 14  ? 376.341 326.488 436.114 1.00 95.78  ? 14  LEU C N   1 
ATOM 5362 C CA  . LEU E 5 14  ? 375.758 327.804 435.943 1.00 95.78  ? 14  LEU C CA  1 
ATOM 5363 C C   . LEU E 5 14  ? 374.303 327.719 436.369 1.00 95.78  ? 14  LEU C C   1 
ATOM 5364 O O   . LEU E 5 14  ? 373.588 326.806 435.954 1.00 95.78  ? 14  LEU C O   1 
ATOM 5365 C CB  . LEU E 5 14  ? 375.881 328.261 434.494 1.00 95.78  ? 14  LEU C CB  1 
ATOM 5366 C CG  . LEU E 5 14  ? 375.552 329.714 434.195 1.00 95.78  ? 14  LEU C CG  1 
ATOM 5367 C CD1 . LEU E 5 14  ? 376.485 330.606 434.953 1.00 95.78  ? 14  LEU C CD1 1 
ATOM 5368 C CD2 . LEU E 5 14  ? 375.675 329.960 432.717 1.00 95.78  ? 14  LEU C CD2 1 
ATOM 5369 N N   . THR E 5 15  ? 373.872 328.651 437.213 1.00 100.14 ? 15  THR C N   1 
ATOM 5370 C CA  . THR E 5 15  ? 372.546 328.550 437.803 1.00 100.14 ? 15  THR C CA  1 
ATOM 5371 C C   . THR E 5 15  ? 371.429 328.852 436.818 1.00 100.14 ? 15  THR C C   1 
ATOM 5372 O O   . THR E 5 15  ? 370.291 328.437 437.051 1.00 100.14 ? 15  THR C O   1 
ATOM 5373 C CB  . THR E 5 15  ? 372.430 329.488 438.997 1.00 100.14 ? 15  THR C CB  1 
ATOM 5374 O OG1 . THR E 5 15  ? 372.668 330.831 438.567 1.00 100.14 ? 15  THR C OG1 1 
ATOM 5375 C CG2 . THR E 5 15  ? 373.446 329.121 440.047 1.00 100.14 ? 15  THR C CG2 1 
ATOM 5376 N N   . SER E 5 16  ? 371.717 329.553 435.730 1.00 103.66 ? 16  SER C N   1 
ATOM 5377 C CA  . SER E 5 16  ? 370.705 329.913 434.744 1.00 103.66 ? 16  SER C CA  1 
ATOM 5378 C C   . SER E 5 16  ? 370.875 329.128 433.449 1.00 103.66 ? 16  SER C C   1 
ATOM 5379 O O   . SER E 5 16  ? 370.608 329.637 432.360 1.00 103.66 ? 16  SER C O   1 
ATOM 5380 C CB  . SER E 5 16  ? 370.735 331.412 434.464 1.00 103.66 ? 16  SER C CB  1 
ATOM 5381 O OG  . SER E 5 16  ? 372.061 331.882 434.335 1.00 103.66 ? 16  SER C OG  1 
ATOM 5382 N N   . ASP E 5 17  ? 371.317 327.879 433.547 1.00 111.07 ? 17  ASP C N   1 
ATOM 5383 C CA  . ASP E 5 17  ? 371.530 327.075 432.357 1.00 111.07 ? 17  ASP C CA  1 
ATOM 5384 C C   . ASP E 5 17  ? 370.213 326.497 431.853 1.00 111.07 ? 17  ASP C C   1 
ATOM 5385 O O   . ASP E 5 17  ? 369.150 326.689 432.443 1.00 111.07 ? 17  ASP C O   1 
ATOM 5386 C CB  . ASP E 5 17  ? 372.558 325.970 432.616 1.00 111.07 ? 17  ASP C CB  1 
ATOM 5387 C CG  . ASP E 5 17  ? 372.204 325.060 433.801 1.00 111.07 ? 17  ASP C CG  1 
ATOM 5388 O OD1 . ASP E 5 17  ? 371.073 325.081 434.329 1.00 111.07 ? 17  ASP C OD1 1 
ATOM 5389 O OD2 . ASP E 5 17  ? 373.094 324.286 434.207 1.00 111.07 ? 17  ASP C OD2 1 
ATOM 5390 N N   . ASP E 5 18  ? 370.289 325.760 430.752 1.00 121.64 ? 18  ASP C N   1 
ATOM 5391 C CA  . ASP E 5 18  ? 369.127 325.044 430.240 1.00 121.64 ? 18  ASP C CA  1 
ATOM 5392 C C   . ASP E 5 18  ? 369.688 323.797 429.567 1.00 121.64 ? 18  ASP C C   1 
ATOM 5393 O O   . ASP E 5 18  ? 370.051 323.836 428.390 1.00 121.64 ? 18  ASP C O   1 
ATOM 5394 C CB  . ASP E 5 18  ? 368.329 325.918 429.278 1.00 121.64 ? 18  ASP C CB  1 
ATOM 5395 C CG  . ASP E 5 18  ? 367.003 325.292 428.833 1.00 121.64 ? 18  ASP C CG  1 
ATOM 5396 O OD1 . ASP E 5 18  ? 366.935 324.105 428.447 1.00 121.64 ? 18  ASP C OD1 1 
ATOM 5397 O OD2 . ASP E 5 18  ? 365.994 326.025 428.876 1.00 121.64 ? 18  ASP C OD2 1 
ATOM 5398 N N   . PHE E 5 19  ? 369.747 322.709 430.313 1.00 123.07 ? 19  PHE C N   1 
ATOM 5399 C CA  . PHE E 5 19  ? 370.181 321.422 429.803 1.00 123.07 ? 19  PHE C CA  1 
ATOM 5400 C C   . PHE E 5 19  ? 369.111 320.384 430.108 1.00 123.07 ? 19  PHE C C   1 
ATOM 5401 O O   . PHE E 5 19  ? 368.285 320.556 431.007 1.00 123.07 ? 19  PHE C O   1 
ATOM 5402 C CB  . PHE E 5 19  ? 371.523 321.018 430.416 1.00 123.07 ? 19  PHE C CB  1 
ATOM 5403 C CG  . PHE E 5 19  ? 372.668 321.890 430.002 1.00 123.07 ? 19  PHE C CG  1 
ATOM 5404 C CD1 . PHE E 5 19  ? 372.859 322.216 428.674 1.00 123.07 ? 19  PHE C CD1 1 
ATOM 5405 C CD2 . PHE E 5 19  ? 373.556 322.378 430.942 1.00 123.07 ? 19  PHE C CD2 1 
ATOM 5406 C CE1 . PHE E 5 19  ? 373.919 323.017 428.288 1.00 123.07 ? 19  PHE C CE1 1 
ATOM 5407 C CE2 . PHE E 5 19  ? 374.616 323.181 430.564 1.00 123.07 ? 19  PHE C CE2 1 
ATOM 5408 C CZ  . PHE E 5 19  ? 374.797 323.500 429.234 1.00 123.07 ? 19  PHE C CZ  1 
ATOM 5409 N N   . GLN E 5 20  ? 369.128 319.298 429.346 1.00 128.62 ? 20  GLN C N   1 
ATOM 5410 C CA  . GLN E 5 20  ? 368.251 318.188 429.657 1.00 128.62 ? 20  GLN C CA  1 
ATOM 5411 C C   . GLN E 5 20  ? 368.743 317.484 430.916 1.00 128.62 ? 20  GLN C C   1 
ATOM 5412 O O   . GLN E 5 20  ? 369.929 317.503 431.251 1.00 128.62 ? 20  GLN C O   1 
ATOM 5413 C CB  . GLN E 5 20  ? 368.183 317.212 428.482 1.00 128.62 ? 20  GLN C CB  1 
ATOM 5414 C CG  . GLN E 5 20  ? 367.355 317.670 427.265 1.00 128.62 ? 20  GLN C CG  1 
ATOM 5415 C CD  . GLN E 5 20  ? 365.862 317.918 427.518 1.00 128.62 ? 20  GLN C CD  1 
ATOM 5416 O OE1 . GLN E 5 20  ? 365.311 317.600 428.575 1.00 128.62 ? 20  GLN C OE1 1 
ATOM 5417 N NE2 . GLN E 5 20  ? 365.203 318.498 426.523 1.00 128.62 ? 20  GLN C NE2 1 
ATOM 5418 N N   . SER E 5 21  ? 367.811 316.853 431.623 1.00 120.75 ? 21  SER C N   1 
ATOM 5419 C CA  . SER E 5 21  ? 368.141 316.306 432.917 1.00 120.75 ? 21  SER C CA  1 
ATOM 5420 C C   . SER E 5 21  ? 367.674 314.864 432.987 1.00 120.75 ? 21  SER C C   1 
ATOM 5421 O O   . SER E 5 21  ? 366.652 314.525 432.374 1.00 120.75 ? 21  SER C O   1 
ATOM 5422 C CB  . SER E 5 21  ? 367.493 317.116 434.037 1.00 120.75 ? 21  SER C CB  1 
ATOM 5423 O OG  . SER E 5 21  ? 366.147 317.410 433.717 1.00 120.75 ? 21  SER C OG  1 
ATOM 5424 N N   . PRO E 5 22  ? 368.393 314.000 433.699 1.00 115.71 ? 22  PRO C N   1 
ATOM 5425 C CA  . PRO E 5 22  ? 367.919 312.623 433.874 1.00 115.71 ? 22  PRO C CA  1 
ATOM 5426 C C   . PRO E 5 22  ? 366.715 312.585 434.803 1.00 115.71 ? 22  PRO C C   1 
ATOM 5427 O O   . PRO E 5 22  ? 366.748 313.134 435.905 1.00 115.71 ? 22  PRO C O   1 
ATOM 5428 C CB  . PRO E 5 22  ? 369.127 311.906 434.483 1.00 115.71 ? 22  PRO C CB  1 
ATOM 5429 C CG  . PRO E 5 22  ? 369.936 312.982 435.106 1.00 115.71 ? 22  PRO C CG  1 
ATOM 5430 C CD  . PRO E 5 22  ? 369.730 314.205 434.280 1.00 115.71 ? 22  PRO C CD  1 
ATOM 5431 N N   . SER E 5 23  ? 365.643 311.949 434.343 1.00 113.88 ? 23  SER C N   1 
ATOM 5432 C CA  . SER E 5 23  ? 364.424 311.865 435.134 1.00 113.88 ? 23  SER C CA  1 
ATOM 5433 C C   . SER E 5 23  ? 364.608 310.864 436.262 1.00 113.88 ? 23  SER C C   1 
ATOM 5434 O O   . SER E 5 23  ? 365.089 309.752 436.039 1.00 113.88 ? 23  SER C O   1 
ATOM 5435 C CB  . SER E 5 23  ? 363.244 311.456 434.261 1.00 113.88 ? 23  SER C CB  1 
ATOM 5436 O OG  . SER E 5 23  ? 362.220 310.884 435.052 1.00 113.88 ? 23  SER C OG  1 
ATOM 5437 N N   . ALA E 5 24  ? 364.230 311.265 437.477 1.00 111.74 ? 24  ALA C N   1 
ATOM 5438 C CA  . ALA E 5 24  ? 364.388 310.378 438.622 1.00 111.74 ? 24  ALA C CA  1 
ATOM 5439 C C   . ALA E 5 24  ? 363.373 309.248 438.586 1.00 111.74 ? 24  ALA C C   1 
ATOM 5440 O O   . ALA E 5 24  ? 363.732 308.078 438.758 1.00 111.74 ? 24  ALA C O   1 
ATOM 5441 C CB  . ALA E 5 24  ? 364.260 311.162 439.924 1.00 111.74 ? 24  ALA C CB  1 
ATOM 5442 N N   . MET E 5 25  ? 362.104 309.574 438.362 1.00 117.45 ? 25  MET C N   1 
ATOM 5443 C CA  . MET E 5 25  ? 361.034 308.583 438.291 1.00 117.45 ? 25  MET C CA  1 
ATOM 5444 C C   . MET E 5 25  ? 360.430 308.611 436.896 1.00 117.45 ? 25  MET C C   1 
ATOM 5445 O O   . MET E 5 25  ? 359.522 309.408 436.620 1.00 117.45 ? 25  MET C O   1 
ATOM 5446 C CB  . MET E 5 25  ? 359.967 308.847 439.349 1.00 117.45 ? 25  MET C CB  1 
ATOM 5447 C CG  . MET E 5 25  ? 360.495 308.893 440.763 1.00 117.45 ? 25  MET C CG  1 
ATOM 5448 S SD  . MET E 5 25  ? 359.216 309.335 441.945 1.00 117.45 ? 25  MET C SD  1 
ATOM 5449 C CE  . MET E 5 25  ? 357.948 308.152 441.513 1.00 117.45 ? 25  MET C CE  1 
ATOM 5450 N N   . PRO E 5 26  ? 360.896 307.768 435.988 1.00 119.06 ? 26  PRO C N   1 
ATOM 5451 C CA  . PRO E 5 26  ? 360.171 307.526 434.742 1.00 119.06 ? 26  PRO C CA  1 
ATOM 5452 C C   . PRO E 5 26  ? 359.031 306.551 435.004 1.00 119.06 ? 26  PRO C C   1 
ATOM 5453 O O   . PRO E 5 26  ? 358.728 306.223 436.149 1.00 119.06 ? 26  PRO C O   1 
ATOM 5454 C CB  . PRO E 5 26  ? 361.230 306.919 433.817 1.00 119.06 ? 26  PRO C CB  1 
ATOM 5455 C CG  . PRO E 5 26  ? 362.526 307.018 434.556 1.00 119.06 ? 26  PRO C CG  1 
ATOM 5456 C CD  . PRO E 5 26  ? 362.180 307.059 436.000 1.00 119.06 ? 26  PRO C CD  1 
ATOM 5457 N N   . GLN E 5 27  ? 358.390 306.124 433.907 1.00 125.35 ? 27  GLN C N   1 
ATOM 5458 C CA  . GLN E 5 27  ? 357.340 305.085 433.859 1.00 125.35 ? 27  GLN C CA  1 
ATOM 5459 C C   . GLN E 5 27  ? 356.200 305.344 434.852 1.00 125.35 ? 27  GLN C C   1 
ATOM 5460 O O   . GLN E 5 27  ? 355.572 304.424 435.379 1.00 125.35 ? 27  GLN C O   1 
ATOM 5461 C CB  . GLN E 5 27  ? 357.946 303.669 434.004 1.00 125.35 ? 27  GLN C CB  1 
ATOM 5462 C CG  . GLN E 5 27  ? 358.488 303.177 435.363 1.00 125.35 ? 27  GLN C CG  1 
ATOM 5463 C CD  . GLN E 5 27  ? 359.578 302.140 435.231 1.00 125.35 ? 27  GLN C CD  1 
ATOM 5464 O OE1 . GLN E 5 27  ? 360.030 301.834 434.129 1.00 125.35 ? 27  GLN C OE1 1 
ATOM 5465 N NE2 . GLN E 5 27  ? 360.007 301.589 436.359 1.00 125.35 ? 27  GLN C NE2 1 
ATOM 5466 N N   . PHE E 5 28  ? 355.879 306.621 435.058 1.00 123.17 ? 28  PHE C N   1 
ATOM 5467 C CA  . PHE E 5 28  ? 354.912 306.992 436.081 1.00 123.17 ? 28  PHE C CA  1 
ATOM 5468 C C   . PHE E 5 28  ? 353.501 307.216 435.555 1.00 123.17 ? 28  PHE C C   1 
ATOM 5469 O O   . PHE E 5 28  ? 352.548 306.912 436.282 1.00 123.17 ? 28  PHE C O   1 
ATOM 5470 C CB  . PHE E 5 28  ? 355.362 308.251 436.824 1.00 123.17 ? 28  PHE C CB  1 
ATOM 5471 C CG  . PHE E 5 28  ? 354.494 308.585 437.992 1.00 123.17 ? 28  PHE C CG  1 
ATOM 5472 C CD1 . PHE E 5 28  ? 354.504 307.790 439.118 1.00 123.17 ? 28  PHE C CD1 1 
ATOM 5473 C CD2 . PHE E 5 28  ? 353.638 309.666 437.949 1.00 123.17 ? 28  PHE C CD2 1 
ATOM 5474 C CE1 . PHE E 5 28  ? 353.691 308.083 440.190 1.00 123.17 ? 28  PHE C CE1 1 
ATOM 5475 C CE2 . PHE E 5 28  ? 352.825 309.962 439.013 1.00 123.17 ? 28  PHE C CE2 1 
ATOM 5476 C CZ  . PHE E 5 28  ? 352.850 309.169 440.135 1.00 123.17 ? 28  PHE C CZ  1 
ATOM 5477 N N   . ASP E 5 29  ? 353.349 307.738 434.329 1.00 124.68 ? 29  ASP C N   1 
ATOM 5478 C CA  . ASP E 5 29  ? 352.057 308.018 433.687 1.00 124.68 ? 29  ASP C CA  1 
ATOM 5479 C C   . ASP E 5 29  ? 351.242 309.005 434.533 1.00 124.68 ? 29  ASP C C   1 
ATOM 5480 O O   . ASP E 5 29  ? 350.272 308.652 435.203 1.00 124.68 ? 29  ASP C O   1 
ATOM 5481 C CB  . ASP E 5 29  ? 351.287 306.718 433.393 1.00 124.68 ? 29  ASP C CB  1 
ATOM 5482 C CG  . ASP E 5 29  ? 350.124 306.909 432.424 1.00 124.68 ? 29  ASP C CG  1 
ATOM 5483 O OD1 . ASP E 5 29  ? 349.197 307.702 432.695 1.00 124.68 ? 29  ASP C OD1 1 
ATOM 5484 O OD2 . ASP E 5 29  ? 350.122 306.216 431.385 1.00 124.68 ? 29  ASP C OD2 1 
ATOM 5485 N N   . VAL E 5 30  ? 351.716 310.254 434.519 1.00 120.56 ? 30  VAL C N   1 
ATOM 5486 C CA  . VAL E 5 30  ? 351.247 311.333 435.388 1.00 120.56 ? 30  VAL C CA  1 
ATOM 5487 C C   . VAL E 5 30  ? 349.780 311.671 435.164 1.00 120.56 ? 30  VAL C C   1 
ATOM 5488 O O   . VAL E 5 30  ? 349.176 311.265 434.166 1.00 120.56 ? 30  VAL C O   1 
ATOM 5489 C CB  . VAL E 5 30  ? 352.095 312.599 435.184 1.00 120.56 ? 30  VAL C CB  1 
ATOM 5490 C CG1 . VAL E 5 30  ? 353.543 312.323 435.490 1.00 120.56 ? 30  VAL C CG1 1 
ATOM 5491 C CG2 . VAL E 5 30  ? 351.937 313.104 433.769 1.00 120.56 ? 30  VAL C CG2 1 
ATOM 5492 N N   . THR E 5 31  ? 349.206 312.416 436.100 1.00 117.67 ? 31  THR C N   1 
ATOM 5493 C CA  . THR E 5 31  ? 347.807 312.821 436.039 1.00 117.67 ? 31  THR C CA  1 
ATOM 5494 C C   . THR E 5 31  ? 347.601 313.817 434.905 1.00 117.67 ? 31  THR C C   1 
ATOM 5495 O O   . THR E 5 31  ? 348.338 314.802 434.817 1.00 117.67 ? 31  THR C O   1 
ATOM 5496 C CB  . THR E 5 31  ? 347.388 313.453 437.355 1.00 117.67 ? 31  THR C CB  1 
ATOM 5497 O OG1 . THR E 5 31  ? 347.908 312.679 438.440 1.00 117.67 ? 31  THR C OG1 1 
ATOM 5498 C CG2 . THR E 5 31  ? 345.884 313.497 437.462 1.00 117.67 ? 31  THR C CG2 1 
ATOM 5499 N N   . PRO E 5 32  ? 346.628 313.599 434.027 1.00 119.83 ? 32  PRO C N   1 
ATOM 5500 C CA  . PRO E 5 32  ? 346.404 314.538 432.924 1.00 119.83 ? 32  PRO C CA  1 
ATOM 5501 C C   . PRO E 5 32  ? 345.773 315.832 433.413 1.00 119.83 ? 32  PRO C C   1 
ATOM 5502 O O   . PRO E 5 32  ? 345.413 315.991 434.580 1.00 119.83 ? 32  PRO C O   1 
ATOM 5503 C CB  . PRO E 5 32  ? 345.466 313.773 431.992 1.00 119.83 ? 32  PRO C CB  1 
ATOM 5504 C CG  . PRO E 5 32  ? 344.764 312.826 432.879 1.00 119.83 ? 32  PRO C CG  1 
ATOM 5505 C CD  . PRO E 5 32  ? 345.760 312.417 433.919 1.00 119.83 ? 32  PRO C CD  1 
ATOM 5506 N N   . GLU E 5 33  ? 345.635 316.770 432.484 1.00 121.67 ? 33  GLU C N   1 
ATOM 5507 C CA  . GLU E 5 33  ? 345.189 318.109 432.822 1.00 121.67 ? 33  GLU C CA  1 
ATOM 5508 C C   . GLU E 5 33  ? 343.679 318.163 433.025 1.00 121.67 ? 33  GLU C C   1 
ATOM 5509 O O   . GLU E 5 33  ? 342.934 317.255 432.649 1.00 121.67 ? 33  GLU C O   1 
ATOM 5510 C CB  . GLU E 5 33  ? 345.581 319.095 431.730 1.00 121.67 ? 33  GLU C CB  1 
ATOM 5511 C CG  . GLU E 5 33  ? 347.058 319.321 431.612 1.00 121.67 ? 33  GLU C CG  1 
ATOM 5512 C CD  . GLU E 5 33  ? 347.374 320.704 431.100 1.00 121.67 ? 33  GLU C CD  1 
ATOM 5513 O OE1 . GLU E 5 33  ? 348.522 320.930 430.673 1.00 121.67 ? 33  GLU C OE1 1 
ATOM 5514 O OE2 . GLU E 5 33  ? 346.472 321.567 431.128 1.00 121.67 ? 33  GLU C OE2 1 
ATOM 5515 N N   . MET E 5 34  ? 343.237 319.259 433.629 1.00 119.79 ? 34  MET C N   1 
ATOM 5516 C CA  . MET E 5 34  ? 341.829 319.553 433.829 1.00 119.79 ? 34  MET C CA  1 
ATOM 5517 C C   . MET E 5 34  ? 341.633 321.046 433.636 1.00 119.79 ? 34  MET C C   1 
ATOM 5518 O O   . MET E 5 34  ? 342.415 321.849 434.150 1.00 119.79 ? 34  MET C O   1 
ATOM 5519 C CB  . MET E 5 34  ? 341.366 319.120 435.224 1.00 119.79 ? 34  MET C CB  1 
ATOM 5520 C CG  . MET E 5 34  ? 339.935 319.490 435.567 1.00 119.79 ? 34  MET C CG  1 
ATOM 5521 S SD  . MET E 5 34  ? 339.597 319.394 437.333 1.00 119.79 ? 34  MET C SD  1 
ATOM 5522 C CE  . MET E 5 34  ? 338.414 320.722 437.519 1.00 119.79 ? 34  MET C CE  1 
ATOM 5523 N N   . GLN E 5 35  ? 340.596 321.416 432.888 1.00 116.35 ? 35  GLN C N   1 
ATOM 5524 C CA  . GLN E 5 35  ? 340.378 322.810 432.527 1.00 116.35 ? 35  GLN C CA  1 
ATOM 5525 C C   . GLN E 5 35  ? 339.897 323.624 433.722 1.00 116.35 ? 35  GLN C C   1 
ATOM 5526 O O   . GLN E 5 35  ? 338.704 323.644 434.033 1.00 116.35 ? 35  GLN C O   1 
ATOM 5527 C CB  . GLN E 5 35  ? 339.379 322.903 431.376 1.00 116.35 ? 35  GLN C CB  1 
ATOM 5528 C CG  . GLN E 5 35  ? 339.179 324.303 430.838 1.00 116.35 ? 35  GLN C CG  1 
ATOM 5529 C CD  . GLN E 5 35  ? 338.239 324.338 429.651 1.00 116.35 ? 35  GLN C CD  1 
ATOM 5530 O OE1 . GLN E 5 35  ? 337.713 323.308 429.230 1.00 116.35 ? 35  GLN C OE1 1 
ATOM 5531 N NE2 . GLN E 5 35  ? 338.018 325.528 429.107 1.00 116.35 ? 35  GLN C NE2 1 
ATOM 5532 N N   . ILE E 5 36  ? 340.829 324.285 434.399 1.00 107.49 ? 36  ILE C N   1 
ATOM 5533 C CA  . ILE E 5 36  ? 340.539 325.133 435.552 1.00 107.49 ? 36  ILE C CA  1 
ATOM 5534 C C   . ILE E 5 36  ? 340.379 326.562 435.051 1.00 107.49 ? 36  ILE C C   1 
ATOM 5535 O O   . ILE E 5 36  ? 341.190 327.015 434.233 1.00 107.49 ? 36  ILE C O   1 
ATOM 5536 C CB  . ILE E 5 36  ? 341.651 325.014 436.605 1.00 107.49 ? 36  ILE C CB  1 
ATOM 5537 C CG1 . ILE E 5 36  ? 341.796 323.558 437.037 1.00 107.49 ? 36  ILE C CG1 1 
ATOM 5538 C CG2 . ILE E 5 36  ? 341.375 325.895 437.801 1.00 107.49 ? 36  ILE C CG2 1 
ATOM 5539 C CD1 . ILE E 5 36  ? 342.816 323.334 438.118 1.00 107.49 ? 36  ILE C CD1 1 
ATOM 5540 N N   . PRO E 5 37  ? 339.353 327.295 435.478 1.00 103.82 ? 37  PRO C N   1 
ATOM 5541 C CA  . PRO E 5 37  ? 339.166 328.657 434.974 1.00 103.82 ? 37  PRO C CA  1 
ATOM 5542 C C   . PRO E 5 37  ? 340.177 329.629 435.552 1.00 103.82 ? 37  PRO C C   1 
ATOM 5543 O O   . PRO E 5 37  ? 340.622 329.497 436.692 1.00 103.82 ? 37  PRO C O   1 
ATOM 5544 C CB  . PRO E 5 37  ? 337.747 329.012 435.431 1.00 103.82 ? 37  PRO C CB  1 
ATOM 5545 C CG  . PRO E 5 37  ? 337.104 327.715 435.740 1.00 103.82 ? 37  PRO C CG  1 
ATOM 5546 C CD  . PRO E 5 37  ? 338.190 326.846 436.255 1.00 103.82 ? 37  PRO C CD  1 
ATOM 5547 N N   . GLY E 5 38  ? 340.532 330.622 434.747 1.00 99.61  ? 38  GLY C N   1 
ATOM 5548 C CA  . GLY E 5 38  ? 341.404 331.683 435.204 1.00 99.61  ? 38  GLY C CA  1 
ATOM 5549 C C   . GLY E 5 38  ? 342.878 331.387 435.050 1.00 99.61  ? 38  GLY C C   1 
ATOM 5550 O O   . GLY E 5 38  ? 343.629 331.448 436.025 1.00 99.61  ? 38  GLY C O   1 
ATOM 5551 N N   . ARG E 5 39  ? 343.309 331.077 433.833 1.00 104.82 ? 39  ARG C N   1 
ATOM 5552 C CA  . ARG E 5 39  ? 344.714 330.802 433.580 1.00 104.82 ? 39  ARG C CA  1 
ATOM 5553 C C   . ARG E 5 39  ? 345.457 332.086 433.249 1.00 104.82 ? 39  ARG C C   1 
ATOM 5554 O O   . ARG E 5 39  ? 345.000 332.891 432.436 1.00 104.82 ? 39  ARG C O   1 
ATOM 5555 C CB  . ARG E 5 39  ? 344.870 329.807 432.436 1.00 104.82 ? 39  ARG C CB  1 
ATOM 5556 C CG  . ARG E 5 39  ? 346.285 329.305 432.268 1.00 104.82 ? 39  ARG C CG  1 
ATOM 5557 C CD  . ARG E 5 39  ? 346.367 328.226 431.221 1.00 104.82 ? 39  ARG C CD  1 
ATOM 5558 N NE  . ARG E 5 39  ? 347.742 327.805 430.995 1.00 104.82 ? 39  ARG C NE  1 
ATOM 5559 C CZ  . ARG E 5 39  ? 348.100 326.895 430.099 1.00 104.82 ? 39  ARG C CZ  1 
ATOM 5560 N NH1 . ARG E 5 39  ? 349.374 326.569 429.955 1.00 104.82 ? 39  ARG C NH1 1 
ATOM 5561 N NH2 . ARG E 5 39  ? 347.182 326.313 429.344 1.00 104.82 ? 39  ARG C NH2 1 
ATOM 5562 N N   . VAL E 5 40  ? 346.612 332.267 433.875 1.00 104.25 ? 40  VAL C N   1 
ATOM 5563 C CA  . VAL E 5 40  ? 347.429 333.460 433.701 1.00 104.25 ? 40  VAL C CA  1 
ATOM 5564 C C   . VAL E 5 40  ? 348.609 333.095 432.815 1.00 104.25 ? 40  VAL C C   1 
ATOM 5565 O O   . VAL E 5 40  ? 349.477 332.315 433.215 1.00 104.25 ? 40  VAL C O   1 
ATOM 5566 C CB  . VAL E 5 40  ? 347.899 334.013 435.049 1.00 104.25 ? 40  VAL C CB  1 
ATOM 5567 C CG1 . VAL E 5 40  ? 348.767 335.218 434.840 1.00 104.25 ? 40  VAL C CG1 1 
ATOM 5568 C CG2 . VAL E 5 40  ? 346.716 334.370 435.894 1.00 104.25 ? 40  VAL C CG2 1 
ATOM 5569 N N   . ASN E 5 41  ? 348.651 333.653 431.609 1.00 113.14 ? 41  ASN C N   1 
ATOM 5570 C CA  . ASN E 5 41  ? 349.778 333.443 430.711 1.00 113.14 ? 41  ASN C CA  1 
ATOM 5571 C C   . ASN E 5 41  ? 350.871 334.482 430.874 1.00 113.14 ? 41  ASN C C   1 
ATOM 5572 O O   . ASN E 5 41  ? 352.011 334.226 430.484 1.00 113.14 ? 41  ASN C O   1 
ATOM 5573 C CB  . ASN E 5 41  ? 349.317 333.457 429.251 1.00 113.14 ? 41  ASN C CB  1 
ATOM 5574 C CG  . ASN E 5 41  ? 348.447 332.274 428.901 1.00 113.14 ? 41  ASN C CG  1 
ATOM 5575 O OD1 . ASN E 5 41  ? 348.934 331.156 428.753 1.00 113.14 ? 41  ASN C OD1 1 
ATOM 5576 N ND2 . ASN E 5 41  ? 347.153 332.518 428.748 1.00 113.14 ? 41  ASN C ND2 1 
ATOM 5577 N N   . ASN E 5 42  ? 350.551 335.645 431.430 1.00 112.94 ? 42  ASN C N   1 
ATOM 5578 C CA  . ASN E 5 42  ? 351.492 336.747 431.510 1.00 112.94 ? 42  ASN C CA  1 
ATOM 5579 C C   . ASN E 5 42  ? 351.204 337.559 432.759 1.00 112.94 ? 42  ASN C C   1 
ATOM 5580 O O   . ASN E 5 42  ? 350.050 337.794 433.114 1.00 112.94 ? 42  ASN C O   1 
ATOM 5581 C CB  . ASN E 5 42  ? 351.406 337.639 430.273 1.00 112.94 ? 42  ASN C CB  1 
ATOM 5582 C CG  . ASN E 5 42  ? 352.683 338.391 430.012 1.00 112.94 ? 42  ASN C CG  1 
ATOM 5583 O OD1 . ASN E 5 42  ? 353.195 339.086 430.884 1.00 112.94 ? 42  ASN C OD1 1 
ATOM 5584 N ND2 . ASN E 5 42  ? 353.210 338.255 428.804 1.00 112.94 ? 42  ASN C ND2 1 
ATOM 5585 N N   . LEU E 5 43  ? 352.272 338.013 433.412 1.00 108.50 ? 43  LEU C N   1 
ATOM 5586 C CA  . LEU E 5 43  ? 352.136 338.750 434.661 1.00 108.50 ? 43  LEU C CA  1 
ATOM 5587 C C   . LEU E 5 43  ? 351.576 340.148 434.488 1.00 108.50 ? 43  LEU C C   1 
ATOM 5588 O O   . LEU E 5 43  ? 351.232 340.777 435.491 1.00 108.50 ? 43  LEU C O   1 
ATOM 5589 C CB  . LEU E 5 43  ? 353.476 338.870 435.374 1.00 108.50 ? 43  LEU C CB  1 
ATOM 5590 C CG  . LEU E 5 43  ? 353.709 337.953 436.559 1.00 108.50 ? 43  LEU C CG  1 
ATOM 5591 C CD1 . LEU E 5 43  ? 354.936 338.421 437.282 1.00 108.50 ? 43  LEU C CD1 1 
ATOM 5592 C CD2 . LEU E 5 43  ? 352.527 337.993 437.478 1.00 108.50 ? 43  LEU C CD2 1 
ATOM 5593 N N   . MET E 5 44  ? 351.497 340.662 433.266 1.00 111.67 ? 44  MET C N   1 
ATOM 5594 C CA  . MET E 5 44  ? 350.880 341.962 433.078 1.00 111.67 ? 44  MET C CA  1 
ATOM 5595 C C   . MET E 5 44  ? 349.380 341.930 433.298 1.00 111.67 ? 44  MET C C   1 
ATOM 5596 O O   . MET E 5 44  ? 348.824 342.948 433.714 1.00 111.67 ? 44  MET C O   1 
ATOM 5597 C CB  . MET E 5 44  ? 351.195 342.505 431.689 1.00 111.67 ? 44  MET C CB  1 
ATOM 5598 C CG  . MET E 5 44  ? 352.437 343.350 431.683 1.00 111.67 ? 44  MET C CG  1 
ATOM 5599 S SD  . MET E 5 44  ? 352.339 344.560 433.007 1.00 111.67 ? 44  MET C SD  1 
ATOM 5600 C CE  . MET E 5 44  ? 354.038 344.611 433.547 1.00 111.67 ? 44  MET C CE  1 
ATOM 5601 N N   . GLU E 5 45  ? 348.731 340.780 433.095 1.00 111.41 ? 45  GLU C N   1 
ATOM 5602 C CA  . GLU E 5 45  ? 347.298 340.624 433.315 1.00 111.41 ? 45  GLU C CA  1 
ATOM 5603 C C   . GLU E 5 45  ? 346.882 340.840 434.763 1.00 111.41 ? 45  GLU C C   1 
ATOM 5604 O O   . GLU E 5 45  ? 345.705 341.109 435.015 1.00 111.41 ? 45  GLU C O   1 
ATOM 5605 C CB  . GLU E 5 45  ? 346.843 339.234 432.873 1.00 111.41 ? 45  GLU C CB  1 
ATOM 5606 C CG  . GLU E 5 45  ? 347.256 338.863 431.468 1.00 111.41 ? 45  GLU C CG  1 
ATOM 5607 C CD  . GLU E 5 45  ? 347.078 337.386 431.181 1.00 111.41 ? 45  GLU C CD  1 
ATOM 5608 O OE1 . GLU E 5 45  ? 348.086 336.650 431.198 1.00 111.41 ? 45  GLU C OE1 1 
ATOM 5609 O OE2 . GLU E 5 45  ? 345.931 336.960 430.937 1.00 111.41 ? 45  GLU C OE2 1 
ATOM 5610 N N   . ILE E 5 46  ? 347.804 340.721 435.714 1.00 106.33 ? 46  ILE C N   1 
ATOM 5611 C CA  . ILE E 5 46  ? 347.502 341.122 437.080 1.00 106.33 ? 46  ILE C CA  1 
ATOM 5612 C C   . ILE E 5 46  ? 347.550 342.639 437.203 1.00 106.33 ? 46  ILE C C   1 
ATOM 5613 O O   . ILE E 5 46  ? 346.731 343.243 437.901 1.00 106.33 ? 46  ILE C O   1 
ATOM 5614 C CB  . ILE E 5 46  ? 348.468 340.423 438.052 1.00 106.33 ? 46  ILE C CB  1 
ATOM 5615 C CG1 . ILE E 5 46  ? 348.310 338.910 437.927 1.00 106.33 ? 46  ILE C CG1 1 
ATOM 5616 C CG2 . ILE E 5 46  ? 348.211 340.845 439.482 1.00 106.33 ? 46  ILE C CG2 1 
ATOM 5617 C CD1 . ILE E 5 46  ? 349.092 338.117 438.939 1.00 106.33 ? 46  ILE C CD1 1 
ATOM 5618 N N   . ALA E 5 47  ? 348.466 343.287 436.486 1.00 110.37 ? 47  ALA C N   1 
ATOM 5619 C CA  . ALA E 5 47  ? 348.613 344.731 436.616 1.00 110.37 ? 47  ALA C CA  1 
ATOM 5620 C C   . ALA E 5 47  ? 347.540 345.513 435.871 1.00 110.37 ? 47  ALA C C   1 
ATOM 5621 O O   . ALA E 5 47  ? 347.424 346.721 436.086 1.00 110.37 ? 47  ALA C O   1 
ATOM 5622 C CB  . ALA E 5 47  ? 349.993 345.167 436.127 1.00 110.37 ? 47  ALA C CB  1 
ATOM 5623 N N   . GLU E 5 48  ? 346.758 344.872 435.001 1.00 114.50 ? 48  GLU C N   1 
ATOM 5624 C CA  . GLU E 5 48  ? 345.753 345.612 434.248 1.00 114.50 ? 48  GLU C CA  1 
ATOM 5625 C C   . GLU E 5 48  ? 344.501 345.930 435.050 1.00 114.50 ? 48  GLU C C   1 
ATOM 5626 O O   . GLU E 5 48  ? 343.743 346.814 434.641 1.00 114.50 ? 48  GLU C O   1 
ATOM 5627 C CB  . GLU E 5 48  ? 345.333 344.854 432.987 1.00 114.50 ? 48  GLU C CB  1 
ATOM 5628 C CG  . GLU E 5 48  ? 346.456 344.372 432.095 1.00 114.50 ? 48  GLU C CG  1 
ATOM 5629 C CD  . GLU E 5 48  ? 346.952 345.404 431.096 1.00 114.50 ? 48  GLU C CD  1 
ATOM 5630 O OE1 . GLU E 5 48  ? 346.971 346.609 431.410 1.00 114.50 ? 48  GLU C OE1 1 
ATOM 5631 O OE2 . GLU E 5 48  ? 347.337 345.003 429.979 1.00 114.50 ? 48  GLU C OE2 1 
ATOM 5632 N N   . VAL E 5 49  ? 344.249 345.241 436.160 1.00 109.09 ? 49  VAL C N   1 
ATOM 5633 C CA  . VAL E 5 49  ? 343.039 345.494 436.931 1.00 109.09 ? 49  VAL C CA  1 
ATOM 5634 C C   . VAL E 5 49  ? 343.257 346.725 437.795 1.00 109.09 ? 49  VAL C C   1 
ATOM 5635 O O   . VAL E 5 49  ? 344.391 347.183 437.967 1.00 109.09 ? 49  VAL C O   1 
ATOM 5636 C CB  . VAL E 5 49  ? 342.647 344.282 437.786 1.00 109.09 ? 49  VAL C CB  1 
ATOM 5637 C CG1 . VAL E 5 49  ? 342.481 343.067 436.908 1.00 109.09 ? 49  VAL C CG1 1 
ATOM 5638 C CG2 . VAL E 5 49  ? 343.674 344.038 438.846 1.00 109.09 ? 49  VAL C CG2 1 
ATOM 5639 N N   . ASP E 5 50  ? 342.177 347.269 438.341 1.00 107.94 ? 50  ASP C N   1 
ATOM 5640 C CA  . ASP E 5 50  ? 342.230 348.502 439.107 1.00 107.94 ? 50  ASP C CA  1 
ATOM 5641 C C   . ASP E 5 50  ? 342.211 348.226 440.605 1.00 107.94 ? 50  ASP C C   1 
ATOM 5642 O O   . ASP E 5 50  ? 341.598 347.266 441.073 1.00 107.94 ? 50  ASP C O   1 
ATOM 5643 C CB  . ASP E 5 50  ? 341.080 349.427 438.712 1.00 107.94 ? 50  ASP C CB  1 
ATOM 5644 C CG  . ASP E 5 50  ? 339.740 348.734 438.733 1.00 107.94 ? 50  ASP C CG  1 
ATOM 5645 O OD1 . ASP E 5 50  ? 339.701 347.503 438.925 1.00 107.94 ? 50  ASP C OD1 1 
ATOM 5646 O OD2 . ASP E 5 50  ? 338.716 349.423 438.553 1.00 107.94 ? 50  ASP C OD2 1 
ATOM 5647 N N   . SER E 5 51  ? 342.908 349.074 441.356 1.00 100.07 ? 51  SER C N   1 
ATOM 5648 C CA  . SER E 5 51  ? 343.040 348.903 442.793 1.00 100.07 ? 51  SER C CA  1 
ATOM 5649 C C   . SER E 5 51  ? 342.927 350.252 443.476 1.00 100.07 ? 51  SER C C   1 
ATOM 5650 O O   . SER E 5 51  ? 343.276 351.282 442.901 1.00 100.07 ? 51  SER C O   1 
ATOM 5651 C CB  . SER E 5 51  ? 344.367 348.259 443.155 1.00 100.07 ? 51  SER C CB  1 
ATOM 5652 O OG  . SER E 5 51  ? 344.634 347.199 442.269 1.00 100.07 ? 51  SER C OG  1 
ATOM 5653 N N   . VAL E 5 52  ? 342.455 350.236 444.703 1.00 95.87  ? 52  VAL C N   1 
ATOM 5654 C CA  . VAL E 5 52  ? 342.254 351.458 445.467 1.00 95.87  ? 52  VAL C CA  1 
ATOM 5655 C C   . VAL E 5 52  ? 343.608 351.935 445.967 1.00 95.87  ? 52  VAL C C   1 
ATOM 5656 O O   . VAL E 5 52  ? 344.463 351.126 446.340 1.00 95.87  ? 52  VAL C O   1 
ATOM 5657 C CB  . VAL E 5 52  ? 341.274 351.213 446.626 1.00 95.87  ? 52  VAL C CB  1 
ATOM 5658 C CG1 . VAL E 5 52  ? 340.702 352.514 447.115 1.00 95.87  ? 52  VAL C CG1 1 
ATOM 5659 C CG2 . VAL E 5 52  ? 340.175 350.286 446.184 1.00 95.87  ? 52  VAL C CG2 1 
ATOM 5660 N N   . VAL E 5 53  ? 343.817 353.241 445.966 1.00 96.33  ? 53  VAL C N   1 
ATOM 5661 C CA  . VAL E 5 53  ? 345.108 353.844 446.288 1.00 96.33  ? 53  VAL C CA  1 
ATOM 5662 C C   . VAL E 5 53  ? 344.993 354.532 447.641 1.00 96.33  ? 53  VAL C C   1 
ATOM 5663 O O   . VAL E 5 53  ? 344.092 355.354 447.826 1.00 96.33  ? 53  VAL C O   1 
ATOM 5664 C CB  . VAL E 5 53  ? 345.548 354.846 445.211 1.00 96.33  ? 53  VAL C CB  1 
ATOM 5665 C CG1 . VAL E 5 53  ? 346.938 355.355 445.499 1.00 96.33  ? 53  VAL C CG1 1 
ATOM 5666 C CG2 . VAL E 5 53  ? 345.494 354.193 443.861 1.00 96.33  ? 53  VAL C CG2 1 
ATOM 5667 N N   . PRO E 5 54  ? 345.870 354.241 448.595 1.00 101.75 ? 54  PRO C N   1 
ATOM 5668 C CA  . PRO E 5 54  ? 345.807 354.901 449.913 1.00 101.75 ? 54  PRO C CA  1 
ATOM 5669 C C   . PRO E 5 54  ? 346.423 356.297 449.927 1.00 101.75 ? 54  PRO C C   1 
ATOM 5670 O O   . PRO E 5 54  ? 347.530 356.535 450.396 1.00 101.75 ? 54  PRO C O   1 
ATOM 5671 C CB  . PRO E 5 54  ? 346.582 353.932 450.806 1.00 101.75 ? 54  PRO C CB  1 
ATOM 5672 C CG  . PRO E 5 54  ? 347.557 353.302 449.897 1.00 101.75 ? 54  PRO C CG  1 
ATOM 5673 C CD  . PRO E 5 54  ? 346.889 353.179 448.562 1.00 101.75 ? 54  PRO C CD  1 
ATOM 5674 N N   . VAL E 5 55  ? 345.671 357.274 449.418 1.00 102.69 ? 55  VAL C N   1 
ATOM 5675 C CA  . VAL E 5 55  ? 346.202 358.628 449.308 1.00 102.69 ? 55  VAL C CA  1 
ATOM 5676 C C   . VAL E 5 55  ? 345.951 359.464 450.551 1.00 102.69 ? 55  VAL C C   1 
ATOM 5677 O O   . VAL E 5 55  ? 346.118 360.686 450.504 1.00 102.69 ? 55  VAL C O   1 
ATOM 5678 C CB  . VAL E 5 55  ? 345.612 359.366 448.100 1.00 102.69 ? 55  VAL C CB  1 
ATOM 5679 C CG1 . VAL E 5 55  ? 346.104 358.749 446.826 1.00 102.69 ? 55  VAL C CG1 1 
ATOM 5680 C CG2 . VAL E 5 55  ? 344.128 359.298 448.155 1.00 102.69 ? 55  VAL C CG2 1 
ATOM 5681 N N   . ASN E 5 56  ? 345.540 358.853 451.654 1.00 106.39 ? 56  ASN C N   1 
ATOM 5682 C CA  . ASN E 5 56  ? 345.268 359.600 452.872 1.00 106.39 ? 56  ASN C CA  1 
ATOM 5683 C C   . ASN E 5 56  ? 345.998 358.985 454.056 1.00 106.39 ? 56  ASN C C   1 
ATOM 5684 O O   . ASN E 5 56  ? 345.366 358.661 455.064 1.00 106.39 ? 56  ASN C O   1 
ATOM 5685 C CB  . ASN E 5 56  ? 343.769 359.652 453.144 1.00 106.39 ? 56  ASN C CB  1 
ATOM 5686 C CG  . ASN E 5 56  ? 343.382 360.805 454.032 1.00 106.39 ? 56  ASN C CG  1 
ATOM 5687 O OD1 . ASN E 5 56  ? 344.168 361.720 454.249 1.00 106.39 ? 56  ASN C OD1 1 
ATOM 5688 N ND2 . ASN E 5 56  ? 342.170 360.764 454.560 1.00 106.39 ? 56  ASN C ND2 1 
ATOM 5689 N N   . ASN E 5 57  ? 347.311 358.778 453.920 1.00 109.22 ? 57  ASN C N   1 
ATOM 5690 C CA  . ASN E 5 57  ? 348.125 358.109 454.931 1.00 109.22 ? 57  ASN C CA  1 
ATOM 5691 C C   . ASN E 5 57  ? 348.102 358.815 456.280 1.00 109.22 ? 57  ASN C C   1 
ATOM 5692 O O   . ASN E 5 57  ? 347.531 358.283 457.235 1.00 109.22 ? 57  ASN C O   1 
ATOM 5693 C CB  . ASN E 5 57  ? 349.565 358.006 454.448 1.00 109.22 ? 57  ASN C CB  1 
ATOM 5694 C CG  . ASN E 5 57  ? 349.678 357.310 453.125 1.00 109.22 ? 57  ASN C CG  1 
ATOM 5695 O OD1 . ASN E 5 57  ? 350.115 357.896 452.140 1.00 109.22 ? 57  ASN C OD1 1 
ATOM 5696 N ND2 . ASN E 5 57  ? 349.283 356.049 453.089 1.00 109.22 ? 57  ASN C ND2 1 
ATOM 5697 N N   . THR E 5 58  ? 348.681 360.026 456.328 1.00 117.27 ? 58  THR C N   1 
ATOM 5698 C CA  . THR E 5 58  ? 348.748 360.969 457.474 1.00 117.27 ? 58  THR C CA  1 
ATOM 5699 C C   . THR E 5 58  ? 348.936 360.304 458.844 1.00 117.27 ? 58  THR C C   1 
ATOM 5700 O O   . THR E 5 58  ? 348.297 360.674 459.832 1.00 117.27 ? 58  THR C O   1 
ATOM 5701 C CB  . THR E 5 58  ? 347.559 361.956 457.498 1.00 117.27 ? 58  THR C CB  1 
ATOM 5702 O OG1 . THR E 5 58  ? 347.658 362.777 458.667 1.00 117.27 ? 58  THR C OG1 1 
ATOM 5703 C CG2 . THR E 5 58  ? 346.166 361.306 457.484 1.00 117.27 ? 58  THR C CG2 1 
ATOM 5704 N N   . GLU E 5 59  ? 349.790 359.276 458.886 1.00 120.04 ? 59  GLU C N   1 
ATOM 5705 C CA  . GLU E 5 59  ? 350.478 358.756 460.072 1.00 120.04 ? 59  GLU C CA  1 
ATOM 5706 C C   . GLU E 5 59  ? 349.572 358.010 461.055 1.00 120.04 ? 59  GLU C C   1 
ATOM 5707 O O   . GLU E 5 59  ? 350.067 357.266 461.905 1.00 120.04 ? 59  GLU C O   1 
ATOM 5708 C CB  . GLU E 5 59  ? 351.235 359.916 460.752 1.00 120.04 ? 59  GLU C CB  1 
ATOM 5709 C CG  . GLU E 5 59  ? 352.331 359.576 461.767 1.00 120.04 ? 59  GLU C CG  1 
ATOM 5710 C CD  . GLU E 5 59  ? 351.815 359.404 463.182 1.00 120.04 ? 59  GLU C CD  1 
ATOM 5711 O OE1 . GLU E 5 59  ? 350.645 359.759 463.435 1.00 120.04 ? 59  GLU C OE1 1 
ATOM 5712 O OE2 . GLU E 5 59  ? 352.578 358.910 464.039 1.00 120.04 ? 59  GLU C OE2 1 
ATOM 5713 N N   . ASP E 5 60  ? 348.255 358.097 460.902 1.00 118.70 ? 60  ASP C N   1 
ATOM 5714 C CA  . ASP E 5 60  ? 347.368 357.330 461.763 1.00 118.70 ? 60  ASP C CA  1 
ATOM 5715 C C   . ASP E 5 60  ? 346.172 356.740 461.036 1.00 118.70 ? 60  ASP C C   1 
ATOM 5716 O O   . ASP E 5 60  ? 345.317 356.137 461.689 1.00 118.70 ? 60  ASP C O   1 
ATOM 5717 C CB  . ASP E 5 60  ? 346.880 358.186 462.941 1.00 118.70 ? 60  ASP C CB  1 
ATOM 5718 C CG  . ASP E 5 60  ? 346.300 359.505 462.500 1.00 118.70 ? 60  ASP C CG  1 
ATOM 5719 O OD1 . ASP E 5 60  ? 345.092 359.555 462.203 1.00 118.70 ? 60  ASP C OD1 1 
ATOM 5720 O OD2 . ASP E 5 60  ? 347.051 360.500 462.460 1.00 118.70 ? 60  ASP C OD2 1 
ATOM 5721 N N   . ASN E 5 61  ? 346.079 356.891 459.721 1.00 113.03 ? 61  ASN C N   1 
ATOM 5722 C CA  . ASN E 5 61  ? 345.079 356.188 458.938 1.00 113.03 ? 61  ASN C CA  1 
ATOM 5723 C C   . ASN E 5 61  ? 345.649 354.971 458.236 1.00 113.03 ? 61  ASN C C   1 
ATOM 5724 O O   . ASN E 5 61  ? 344.913 354.285 457.524 1.00 113.03 ? 61  ASN C O   1 
ATOM 5725 C CB  . ASN E 5 61  ? 344.453 357.121 457.904 1.00 113.03 ? 61  ASN C CB  1 
ATOM 5726 C CG  . ASN E 5 61  ? 343.906 358.377 458.517 1.00 113.03 ? 61  ASN C CG  1 
ATOM 5727 O OD1 . ASN E 5 61  ? 343.913 358.538 459.732 1.00 113.03 ? 61  ASN C OD1 1 
ATOM 5728 N ND2 . ASN E 5 61  ? 343.415 359.278 457.681 1.00 113.03 ? 61  ASN C ND2 1 
ATOM 5729 N N   . VAL E 5 62  ? 346.940 354.687 458.413 1.00 113.91 ? 62  VAL C N   1 
ATOM 5730 C CA  . VAL E 5 62  ? 347.537 353.569 457.698 1.00 113.91 ? 62  VAL C CA  1 
ATOM 5731 C C   . VAL E 5 62  ? 347.132 352.241 458.321 1.00 113.91 ? 62  VAL C C   1 
ATOM 5732 O O   . VAL E 5 62  ? 347.059 351.221 457.627 1.00 113.91 ? 62  VAL C O   1 
ATOM 5733 C CB  . VAL E 5 62  ? 349.062 353.743 457.628 1.00 113.91 ? 62  VAL C CB  1 
ATOM 5734 C CG1 . VAL E 5 62  ? 349.384 354.937 456.776 1.00 113.91 ? 62  VAL C CG1 1 
ATOM 5735 C CG2 . VAL E 5 62  ? 349.645 353.942 459.008 1.00 113.91 ? 62  VAL C CG2 1 
ATOM 5736 N N   . SER E 5 63  ? 346.869 352.218 459.621 1.00 113.31 ? 63  SER C N   1 
ATOM 5737 C CA  . SER E 5 63  ? 346.294 351.044 460.273 1.00 113.31 ? 63  SER C CA  1 
ATOM 5738 C C   . SER E 5 63  ? 344.786 351.179 460.398 1.00 113.31 ? 63  SER C C   1 
ATOM 5739 O O   . SER E 5 63  ? 344.223 350.990 461.474 1.00 113.31 ? 63  SER C O   1 
ATOM 5740 C CB  . SER E 5 63  ? 346.934 350.839 461.637 1.00 113.31 ? 63  SER C CB  1 
ATOM 5741 O OG  . SER E 5 63  ? 346.539 351.866 462.527 1.00 113.31 ? 63  SER C OG  1 
ATOM 5742 N N   . SER E 5 64  ? 344.118 351.495 459.292 1.00 107.57 ? 64  SER C N   1 
ATOM 5743 C CA  . SER E 5 64  ? 342.678 351.712 459.278 1.00 107.57 ? 64  SER C CA  1 
ATOM 5744 C C   . SER E 5 64  ? 342.195 351.644 457.839 1.00 107.57 ? 64  SER C C   1 
ATOM 5745 O O   . SER E 5 64  ? 342.984 351.496 456.905 1.00 107.57 ? 64  SER C O   1 
ATOM 5746 C CB  . SER E 5 64  ? 342.302 353.057 459.901 1.00 107.57 ? 64  SER C CB  1 
ATOM 5747 O OG  . SER E 5 64  ? 340.910 353.280 459.795 1.00 107.57 ? 64  SER C OG  1 
ATOM 5748 N N   . LEU E 5 65  ? 340.884 351.760 457.669 1.00 104.36 ? 65  LEU C N   1 
ATOM 5749 C CA  . LEU E 5 65  ? 340.283 351.893 456.352 1.00 104.36 ? 65  LEU C CA  1 
ATOM 5750 C C   . LEU E 5 65  ? 340.124 353.342 455.931 1.00 104.36 ? 65  LEU C C   1 
ATOM 5751 O O   . LEU E 5 65  ? 339.573 353.604 454.859 1.00 104.36 ? 65  LEU C O   1 
ATOM 5752 C CB  . LEU E 5 65  ? 338.922 351.206 456.314 1.00 104.36 ? 65  LEU C CB  1 
ATOM 5753 C CG  . LEU E 5 65  ? 338.907 349.825 455.677 1.00 104.36 ? 65  LEU C CG  1 
ATOM 5754 C CD1 . LEU E 5 65  ? 337.485 349.328 455.576 1.00 104.36 ? 65  LEU C CD1 1 
ATOM 5755 C CD2 . LEU E 5 65  ? 339.555 349.882 454.316 1.00 104.36 ? 65  LEU C CD2 1 
ATOM 5756 N N   . LYS E 5 66  ? 340.587 354.284 456.749 1.00 106.73 ? 66  LYS C N   1 
ATOM 5757 C CA  . LYS E 5 66  ? 340.543 355.696 456.406 1.00 106.73 ? 66  LYS C CA  1 
ATOM 5758 C C   . LYS E 5 66  ? 341.651 356.108 455.453 1.00 106.73 ? 66  LYS C C   1 
ATOM 5759 O O   . LYS E 5 66  ? 341.680 357.268 455.034 1.00 106.73 ? 66  LYS C O   1 
ATOM 5760 C CB  . LYS E 5 66  ? 340.634 356.546 457.670 1.00 106.73 ? 66  LYS C CB  1 
ATOM 5761 C CG  . LYS E 5 66  ? 339.448 356.418 458.586 1.00 106.73 ? 66  LYS C CG  1 
ATOM 5762 C CD  . LYS E 5 66  ? 339.297 357.672 459.414 1.00 106.73 ? 66  LYS C CD  1 
ATOM 5763 C CE  . LYS E 5 66  ? 338.005 357.658 460.200 1.00 106.73 ? 66  LYS C CE  1 
ATOM 5764 N NZ  . LYS E 5 66  ? 337.756 358.970 460.854 1.00 106.73 ? 66  LYS C NZ  1 
ATOM 5765 N N   . ALA E 5 67  ? 342.564 355.201 455.114 1.00 103.03 ? 67  ALA C N   1 
ATOM 5766 C CA  . ALA E 5 67  ? 343.644 355.534 454.204 1.00 103.03 ? 67  ALA C CA  1 
ATOM 5767 C C   . ALA E 5 67  ? 343.157 355.754 452.784 1.00 103.03 ? 67  ALA C C   1 
ATOM 5768 O O   . ALA E 5 67  ? 343.801 356.488 452.031 1.00 103.03 ? 67  ALA C O   1 
ATOM 5769 C CB  . ALA E 5 67  ? 344.698 354.432 454.218 1.00 103.03 ? 67  ALA C CB  1 
ATOM 5770 N N   . TYR E 5 68  ? 342.036 355.154 452.404 1.00 100.67 ? 68  TYR C N   1 
ATOM 5771 C CA  . TYR E 5 68  ? 341.567 355.227 451.031 1.00 100.67 ? 68  TYR C CA  1 
ATOM 5772 C C   . TYR E 5 68  ? 340.565 356.345 450.790 1.00 100.67 ? 68  TYR C C   1 
ATOM 5773 O O   . TYR E 5 68  ? 340.277 356.649 449.630 1.00 100.67 ? 68  TYR C O   1 
ATOM 5774 C CB  . TYR E 5 68  ? 340.940 353.895 450.625 1.00 100.67 ? 68  TYR C CB  1 
ATOM 5775 C CG  . TYR E 5 68  ? 341.837 352.702 450.842 1.00 100.67 ? 68  TYR C CG  1 
ATOM 5776 C CD1 . TYR E 5 68  ? 342.882 352.435 449.979 1.00 100.67 ? 68  TYR C CD1 1 
ATOM 5777 C CD2 . TYR E 5 68  ? 341.632 351.842 451.903 1.00 100.67 ? 68  TYR C CD2 1 
ATOM 5778 C CE1 . TYR E 5 68  ? 343.696 351.350 450.165 1.00 100.67 ? 68  TYR C CE1 1 
ATOM 5779 C CE2 . TYR E 5 68  ? 342.445 350.754 452.098 1.00 100.67 ? 68  TYR C CE2 1 
ATOM 5780 C CZ  . TYR E 5 68  ? 343.475 350.516 451.224 1.00 100.67 ? 68  TYR C CZ  1 
ATOM 5781 O OH  . TYR E 5 68  ? 344.296 349.435 451.404 1.00 100.67 ? 68  TYR C OH  1 
ATOM 5782 N N   . GLN E 5 69  ? 340.034 356.964 451.838 1.00 104.86 ? 69  GLN C N   1 
ATOM 5783 C CA  . GLN E 5 69  ? 339.033 358.010 451.706 1.00 104.86 ? 69  GLN C CA  1 
ATOM 5784 C C   . GLN E 5 69  ? 339.695 359.378 451.671 1.00 104.86 ? 69  GLN C C   1 
ATOM 5785 O O   . GLN E 5 69  ? 340.514 359.702 452.534 1.00 104.86 ? 69  GLN C O   1 
ATOM 5786 C CB  . GLN E 5 69  ? 338.038 357.975 452.863 1.00 104.86 ? 69  GLN C CB  1 
ATOM 5787 C CG  . GLN E 5 69  ? 337.723 356.601 453.393 1.00 104.86 ? 69  GLN C CG  1 
ATOM 5788 C CD  . GLN E 5 69  ? 336.874 356.661 454.643 1.00 104.86 ? 69  GLN C CD  1 
ATOM 5789 O OE1 . GLN E 5 69  ? 336.536 357.740 455.123 1.00 104.86 ? 69  GLN C OE1 1 
ATOM 5790 N NE2 . GLN E 5 69  ? 336.523 355.501 455.178 1.00 104.86 ? 69  GLN C NE2 1 
ATOM 5791 N N   . ILE E 5 70  ? 339.324 360.185 450.687 1.00 106.44 ? 70  ILE C N   1 
ATOM 5792 C CA  . ILE E 5 70  ? 339.738 361.582 450.609 1.00 106.44 ? 70  ILE C CA  1 
ATOM 5793 C C   . ILE E 5 70  ? 338.637 362.425 451.239 1.00 106.44 ? 70  ILE C C   1 
ATOM 5794 O O   . ILE E 5 70  ? 337.514 362.435 450.718 1.00 106.44 ? 70  ILE C O   1 
ATOM 5795 C CB  . ILE E 5 70  ? 339.988 362.017 449.163 1.00 106.44 ? 70  ILE C CB  1 
ATOM 5796 C CG1 . ILE E 5 70  ? 340.935 361.046 448.480 1.00 106.44 ? 70  ILE C CG1 1 
ATOM 5797 C CG2 . ILE E 5 70  ? 340.549 363.414 449.131 1.00 106.44 ? 70  ILE C CG2 1 
ATOM 5798 C CD1 . ILE E 5 70  ? 341.142 361.332 447.022 1.00 106.44 ? 70  ILE C CD1 1 
ATOM 5799 N N   . PRO E 5 71  ? 338.898 363.126 452.340 1.00 109.86 ? 71  PRO C N   1 
ATOM 5800 C CA  . PRO E 5 71  ? 337.839 363.913 452.982 1.00 109.86 ? 71  PRO C CA  1 
ATOM 5801 C C   . PRO E 5 71  ? 337.519 365.158 452.169 1.00 109.86 ? 71  PRO C C   1 
ATOM 5802 O O   . PRO E 5 71  ? 338.395 365.978 451.891 1.00 109.86 ? 71  PRO C O   1 
ATOM 5803 C CB  . PRO E 5 71  ? 338.440 364.276 454.345 1.00 109.86 ? 71  PRO C CB  1 
ATOM 5804 C CG  . PRO E 5 71  ? 339.599 363.356 454.519 1.00 109.86 ? 71  PRO C CG  1 
ATOM 5805 C CD  . PRO E 5 71  ? 340.122 363.106 453.148 1.00 109.86 ? 71  PRO C CD  1 
ATOM 5806 N N   . VAL E 5 72  ? 336.253 365.289 451.786 1.00 115.46 ? 72  VAL C N   1 
ATOM 5807 C CA  . VAL E 5 72  ? 335.764 366.432 451.030 1.00 115.46 ? 72  VAL C CA  1 
ATOM 5808 C C   . VAL E 5 72  ? 334.631 367.055 451.828 1.00 115.46 ? 72  VAL C C   1 
ATOM 5809 O O   . VAL E 5 72  ? 333.621 366.394 452.092 1.00 115.46 ? 72  VAL C O   1 
ATOM 5810 C CB  . VAL E 5 72  ? 335.282 366.031 449.627 1.00 115.46 ? 72  VAL C CB  1 
ATOM 5811 C CG1 . VAL E 5 72  ? 334.493 367.153 448.991 1.00 115.46 ? 72  VAL C CG1 1 
ATOM 5812 C CG2 . VAL E 5 72  ? 336.457 365.663 448.755 1.00 115.46 ? 72  VAL C CG2 1 
ATOM 5813 N N   . GLN E 5 73  ? 334.799 368.306 452.226 1.00 125.97 ? 73  GLN C N   1 
ATOM 5814 C CA  . GLN E 5 73  ? 333.752 369.033 452.924 1.00 125.97 ? 73  GLN C CA  1 
ATOM 5815 C C   . GLN E 5 73  ? 333.551 370.392 452.268 1.00 125.97 ? 73  GLN C C   1 
ATOM 5816 O O   . GLN E 5 73  ? 334.394 370.875 451.511 1.00 125.97 ? 73  GLN C O   1 
ATOM 5817 C CB  . GLN E 5 73  ? 334.083 369.188 454.409 1.00 125.97 ? 73  GLN C CB  1 
ATOM 5818 C CG  . GLN E 5 73  ? 335.096 370.266 454.702 1.00 125.97 ? 73  GLN C CG  1 
ATOM 5819 C CD  . GLN E 5 73  ? 336.506 369.731 454.732 1.00 125.97 ? 73  GLN C CD  1 
ATOM 5820 O OE1 . GLN E 5 73  ? 336.720 368.530 454.876 1.00 125.97 ? 73  GLN C OE1 1 
ATOM 5821 N NE2 . GLN E 5 73  ? 337.480 370.620 454.593 1.00 125.97 ? 73  GLN C NE2 1 
ATOM 5822 N N   . SER E 5 74  ? 332.416 371.008 452.567 1.00 131.45 ? 74  SER C N   1 
ATOM 5823 C CA  . SER E 5 74  ? 332.077 372.322 452.042 1.00 131.45 ? 74  SER C CA  1 
ATOM 5824 C C   . SER E 5 74  ? 332.643 373.377 452.979 1.00 131.45 ? 74  SER C C   1 
ATOM 5825 O O   . SER E 5 74  ? 332.045 373.675 454.017 1.00 131.45 ? 74  SER C O   1 
ATOM 5826 C CB  . SER E 5 74  ? 330.565 372.478 451.908 1.00 131.45 ? 74  SER C CB  1 
ATOM 5827 O OG  . SER E 5 74  ? 329.943 372.403 453.177 1.00 131.45 ? 74  SER C OG  1 
ATOM 5828 N N   . ASN E 5 75  ? 333.784 373.943 452.610 1.00 139.15 ? 75  ASN C N   1 
ATOM 5829 C CA  . ASN E 5 75  ? 334.468 374.926 453.432 1.00 139.15 ? 75  ASN C CA  1 
ATOM 5830 C C   . ASN E 5 75  ? 333.966 376.320 453.087 1.00 139.15 ? 75  ASN C C   1 
ATOM 5831 O O   . ASN E 5 75  ? 333.033 376.496 452.300 1.00 139.15 ? 75  ASN C O   1 
ATOM 5832 C CB  . ASN E 5 75  ? 335.986 374.844 453.241 1.00 139.15 ? 75  ASN C CB  1 
ATOM 5833 C CG  . ASN E 5 75  ? 336.402 375.080 451.809 1.00 139.15 ? 75  ASN C CG  1 
ATOM 5834 O OD1 . ASN E 5 75  ? 335.645 374.807 450.880 1.00 139.15 ? 75  ASN C OD1 1 
ATOM 5835 N ND2 . ASN E 5 75  ? 337.611 375.591 451.620 1.00 139.15 ? 75  ASN C ND2 1 
ATOM 5836 N N   . SER E 5 76  ? 334.600 377.320 453.694 1.00 145.74 ? 76  SER C N   1 
ATOM 5837 C CA  . SER E 5 76  ? 334.272 378.713 453.438 1.00 145.74 ? 76  SER C CA  1 
ATOM 5838 C C   . SER E 5 76  ? 335.287 379.406 452.542 1.00 145.74 ? 76  SER C C   1 
ATOM 5839 O O   . SER E 5 76  ? 335.024 380.522 452.083 1.00 145.74 ? 76  SER C O   1 
ATOM 5840 C CB  . SER E 5 76  ? 334.158 379.480 454.759 1.00 145.74 ? 76  SER C CB  1 
ATOM 5841 O OG  . SER E 5 76  ? 335.229 379.151 455.625 1.00 145.74 ? 76  SER C OG  1 
ATOM 5842 N N   . ASP E 5 77  ? 336.428 378.778 452.282 1.00 149.66 ? 77  ASP C N   1 
ATOM 5843 C CA  . ASP E 5 77  ? 337.455 379.384 451.452 1.00 149.66 ? 77  ASP C CA  1 
ATOM 5844 C C   . ASP E 5 77  ? 337.183 379.119 449.977 1.00 149.66 ? 77  ASP C C   1 
ATOM 5845 O O   . ASP E 5 77  ? 336.769 378.024 449.583 1.00 149.66 ? 77  ASP C O   1 
ATOM 5846 C CB  . ASP E 5 77  ? 338.831 378.843 451.831 1.00 149.66 ? 77  ASP C CB  1 
ATOM 5847 C CG  . ASP E 5 77  ? 339.554 379.731 452.817 1.00 149.66 ? 77  ASP C CG  1 
ATOM 5848 O OD1 . ASP E 5 77  ? 339.006 380.795 453.170 1.00 149.66 ? 77  ASP C OD1 1 
ATOM 5849 O OD2 . ASP E 5 77  ? 340.669 379.365 453.243 1.00 149.66 ? 77  ASP C OD2 1 
ATOM 5850 N N   . ASN E 5 78  ? 337.434 380.135 449.158 1.00 149.46 ? 78  ASN C N   1 
ATOM 5851 C CA  . ASN E 5 78  ? 337.195 380.065 447.718 1.00 149.46 ? 78  ASN C CA  1 
ATOM 5852 C C   . ASN E 5 78  ? 338.448 379.494 447.063 1.00 149.46 ? 78  ASN C C   1 
ATOM 5853 O O   . ASN E 5 78  ? 339.418 380.206 446.804 1.00 149.46 ? 78  ASN C O   1 
ATOM 5854 C CB  . ASN E 5 78  ? 336.842 381.439 447.162 1.00 149.46 ? 78  ASN C CB  1 
ATOM 5855 C CG  . ASN E 5 78  ? 335.853 381.368 446.016 1.00 149.46 ? 78  ASN C CG  1 
ATOM 5856 O OD1 . ASN E 5 78  ? 335.057 380.434 445.923 1.00 149.46 ? 78  ASN C OD1 1 
ATOM 5857 N ND2 . ASN E 5 78  ? 335.899 382.360 445.134 1.00 149.46 ? 78  ASN C ND2 1 
ATOM 5858 N N   . GLY E 5 79  ? 338.428 378.192 446.804 1.00 134.80 ? 79  GLY C N   1 
ATOM 5859 C CA  . GLY E 5 79  ? 339.541 377.548 446.140 1.00 134.80 ? 79  GLY C CA  1 
ATOM 5860 C C   . GLY E 5 79  ? 340.577 377.038 447.116 1.00 134.80 ? 79  GLY C C   1 
ATOM 5861 O O   . GLY E 5 79  ? 341.208 377.823 447.828 1.00 134.80 ? 79  GLY C O   1 
ATOM 5862 N N   . LYS E 5 80  ? 340.770 375.724 447.148 1.00 121.91 ? 80  LYS C N   1 
ATOM 5863 C CA  . LYS E 5 80  ? 341.701 375.114 448.081 1.00 121.91 ? 80  LYS C CA  1 
ATOM 5864 C C   . LYS E 5 80  ? 342.110 373.762 447.527 1.00 121.91 ? 80  LYS C C   1 
ATOM 5865 O O   . LYS E 5 80  ? 341.360 373.134 446.779 1.00 121.91 ? 80  LYS C O   1 
ATOM 5866 C CB  . LYS E 5 80  ? 341.079 374.967 449.474 1.00 121.91 ? 80  LYS C CB  1 
ATOM 5867 C CG  . LYS E 5 80  ? 342.082 374.828 450.607 1.00 121.91 ? 80  LYS C CG  1 
ATOM 5868 C CD  . LYS E 5 80  ? 342.932 376.079 450.775 1.00 121.91 ? 80  LYS C CD  1 
ATOM 5869 C CE  . LYS E 5 80  ? 342.081 377.308 451.031 1.00 121.91 ? 80  LYS C CE  1 
ATOM 5870 N NZ  . LYS E 5 80  ? 342.869 378.429 451.604 1.00 121.91 ? 80  LYS C NZ  1 
ATOM 5871 N N   . GLN E 5 81  ? 343.309 373.329 447.892 1.00 115.77 ? 81  GLN C N   1 
ATOM 5872 C CA  . GLN E 5 81  ? 343.840 372.060 447.426 1.00 115.77 ? 81  GLN C CA  1 
ATOM 5873 C C   . GLN E 5 81  ? 343.154 370.916 448.156 1.00 115.77 ? 81  GLN C C   1 
ATOM 5874 O O   . GLN E 5 81  ? 343.129 370.886 449.389 1.00 115.77 ? 81  GLN C O   1 
ATOM 5875 C CB  . GLN E 5 81  ? 345.349 372.007 447.645 1.00 115.77 ? 81  GLN C CB  1 
ATOM 5876 C CG  . GLN E 5 81  ? 345.996 370.738 447.163 1.00 115.77 ? 81  GLN C CG  1 
ATOM 5877 C CD  . GLN E 5 81  ? 347.472 370.914 446.932 1.00 115.77 ? 81  GLN C CD  1 
ATOM 5878 O OE1 . GLN E 5 81  ? 347.980 372.032 446.942 1.00 115.77 ? 81  GLN C OE1 1 
ATOM 5879 N NE2 . GLN E 5 81  ? 348.175 369.811 446.728 1.00 115.77 ? 81  GLN C NE2 1 
ATOM 5880 N N   . VAL E 5 82  ? 342.591 369.983 447.392 1.00 110.84 ? 82  VAL C N   1 
ATOM 5881 C CA  . VAL E 5 82  ? 341.941 368.824 447.991 1.00 110.84 ? 82  VAL C CA  1 
ATOM 5882 C C   . VAL E 5 82  ? 342.973 367.775 448.373 1.00 110.84 ? 82  VAL C C   1 
ATOM 5883 O O   . VAL E 5 82  ? 343.065 367.364 449.534 1.00 110.84 ? 82  VAL C O   1 
ATOM 5884 C CB  . VAL E 5 82  ? 340.877 368.250 447.041 1.00 110.84 ? 82  VAL C CB  1 
ATOM 5885 C CG1 . VAL E 5 82  ? 340.322 366.964 447.594 1.00 110.84 ? 82  VAL C CG1 1 
ATOM 5886 C CG2 . VAL E 5 82  ? 339.768 369.244 446.851 1.00 110.84 ? 82  VAL C CG2 1 
ATOM 5887 N N   . PHE E 5 83  ? 343.765 367.329 447.404 1.00 108.45 ? 83  PHE C N   1 
ATOM 5888 C CA  . PHE E 5 83  ? 344.888 366.445 447.679 1.00 108.45 ? 83  PHE C CA  1 
ATOM 5889 C C   . PHE E 5 83  ? 345.982 366.725 446.661 1.00 108.45 ? 83  PHE C C   1 
ATOM 5890 O O   . PHE E 5 83  ? 345.875 367.640 445.841 1.00 108.45 ? 83  PHE C O   1 
ATOM 5891 C CB  . PHE E 5 83  ? 344.464 364.970 447.673 1.00 108.45 ? 83  PHE C CB  1 
ATOM 5892 C CG  . PHE E 5 83  ? 343.949 364.475 446.353 1.00 108.45 ? 83  PHE C CG  1 
ATOM 5893 C CD1 . PHE E 5 83  ? 342.607 364.569 446.048 1.00 108.45 ? 83  PHE C CD1 1 
ATOM 5894 C CD2 . PHE E 5 83  ? 344.796 363.869 445.439 1.00 108.45 ? 83  PHE C CD2 1 
ATOM 5895 C CE1 . PHE E 5 83  ? 342.126 364.103 444.852 1.00 108.45 ? 83  PHE C CE1 1 
ATOM 5896 C CE2 . PHE E 5 83  ? 344.319 363.411 444.239 1.00 108.45 ? 83  PHE C CE2 1 
ATOM 5897 C CZ  . PHE E 5 83  ? 342.984 363.529 443.947 1.00 108.45 ? 83  PHE C CZ  1 
ATOM 5898 N N   . GLY E 5 84  ? 347.037 365.925 446.717 1.00 108.17 ? 84  GLY C N   1 
ATOM 5899 C CA  . GLY E 5 84  ? 348.123 366.014 445.768 1.00 108.17 ? 84  GLY C CA  1 
ATOM 5900 C C   . GLY E 5 84  ? 349.222 365.044 446.130 1.00 108.17 ? 84  GLY C C   1 
ATOM 5901 O O   . GLY E 5 84  ? 349.601 364.942 447.298 1.00 108.17 ? 84  GLY C O   1 
ATOM 5902 N N   . PHE E 5 85  ? 349.737 364.316 445.145 1.00 104.34 ? 85  PHE C N   1 
ATOM 5903 C CA  . PHE E 5 85  ? 350.798 363.369 445.398 1.00 104.34 ? 85  PHE C CA  1 
ATOM 5904 C C   . PHE E 5 85  ? 351.694 363.312 444.172 1.00 104.34 ? 85  PHE C C   1 
ATOM 5905 O O   . PHE E 5 85  ? 351.201 363.422 443.042 1.00 104.34 ? 85  PHE C O   1 
ATOM 5906 C CB  . PHE E 5 85  ? 350.264 361.963 445.741 1.00 104.34 ? 85  PHE C CB  1 
ATOM 5907 C CG  . PHE E 5 85  ? 349.383 361.345 444.685 1.00 104.34 ? 85  PHE C CG  1 
ATOM 5908 C CD1 . PHE E 5 85  ? 348.021 361.578 444.679 1.00 104.34 ? 85  PHE C CD1 1 
ATOM 5909 C CD2 . PHE E 5 85  ? 349.910 360.486 443.738 1.00 104.34 ? 85  PHE C CD2 1 
ATOM 5910 C CE1 . PHE E 5 85  ? 347.214 361.000 443.729 1.00 104.34 ? 85  PHE C CE1 1 
ATOM 5911 C CE2 . PHE E 5 85  ? 349.105 359.909 442.787 1.00 104.34 ? 85  PHE C CE2 1 
ATOM 5912 C CZ  . PHE E 5 85  ? 347.758 360.164 442.785 1.00 104.34 ? 85  PHE C CZ  1 
ATOM 5913 N N   . PRO E 5 86  ? 352.998 363.155 444.354 1.00 112.12 ? 86  PRO C N   1 
ATOM 5914 C CA  . PRO E 5 86  ? 353.896 363.052 443.206 1.00 112.12 ? 86  PRO C CA  1 
ATOM 5915 C C   . PRO E 5 86  ? 353.794 361.682 442.559 1.00 112.12 ? 86  PRO C C   1 
ATOM 5916 O O   . PRO E 5 86  ? 353.191 360.752 443.089 1.00 112.12 ? 86  PRO C O   1 
ATOM 5917 C CB  . PRO E 5 86  ? 355.274 363.261 443.829 1.00 112.12 ? 86  PRO C CB  1 
ATOM 5918 C CG  . PRO E 5 86  ? 355.122 362.692 445.183 1.00 112.12 ? 86  PRO C CG  1 
ATOM 5919 C CD  . PRO E 5 86  ? 353.741 363.080 445.623 1.00 112.12 ? 86  PRO C CD  1 
ATOM 5920 N N   . LEU E 5 87  ? 354.406 361.571 441.387 1.00 118.21 ? 87  LEU C N   1 
ATOM 5921 C CA  . LEU E 5 87  ? 354.525 360.292 440.706 1.00 118.21 ? 87  LEU C CA  1 
ATOM 5922 C C   . LEU E 5 87  ? 355.963 359.793 440.715 1.00 118.21 ? 87  LEU C C   1 
ATOM 5923 O O   . LEU E 5 87  ? 356.320 358.928 439.907 1.00 118.21 ? 87  LEU C O   1 
ATOM 5924 C CB  . LEU E 5 87  ? 353.991 360.394 439.278 1.00 118.21 ? 87  LEU C CB  1 
ATOM 5925 C CG  . LEU E 5 87  ? 352.514 360.760 439.137 1.00 118.21 ? 87  LEU C CG  1 
ATOM 5926 C CD1 . LEU E 5 87  ? 352.056 360.589 437.706 1.00 118.21 ? 87  LEU C CD1 1 
ATOM 5927 C CD2 . LEU E 5 87  ? 351.666 359.918 440.058 1.00 118.21 ? 87  LEU C CD2 1 
ATOM 5928 N N   . GLN E 5 88  ? 356.792 360.345 441.605 1.00 128.72 ? 88  GLN C N   1 
ATOM 5929 C CA  . GLN E 5 88  ? 358.179 359.915 441.791 1.00 128.72 ? 88  GLN C CA  1 
ATOM 5930 C C   . GLN E 5 88  ? 358.201 358.466 442.251 1.00 128.72 ? 88  GLN C C   1 
ATOM 5931 O O   . GLN E 5 88  ? 357.764 358.177 443.372 1.00 128.72 ? 88  GLN C O   1 
ATOM 5932 C CB  . GLN E 5 88  ? 358.875 360.807 442.813 1.00 128.72 ? 88  GLN C CB  1 
ATOM 5933 C CG  . GLN E 5 88  ? 360.341 360.485 443.051 1.00 128.72 ? 88  GLN C CG  1 
ATOM 5934 C CD  . GLN E 5 88  ? 361.273 361.302 442.178 1.00 128.72 ? 88  GLN C CD  1 
ATOM 5935 O OE1 . GLN E 5 88  ? 361.067 362.497 441.979 1.00 128.72 ? 88  GLN C OE1 1 
ATOM 5936 N NE2 . GLN E 5 88  ? 362.312 360.661 441.660 1.00 128.72 ? 88  GLN C NE2 1 
ATOM 5937 N N   . PRO E 5 89  ? 358.687 357.537 441.438 1.00 126.26 ? 89  PRO C N   1 
ATOM 5938 C CA  . PRO E 5 89  ? 358.428 356.118 441.687 1.00 126.26 ? 89  PRO C CA  1 
ATOM 5939 C C   . PRO E 5 89  ? 359.246 355.542 442.831 1.00 126.26 ? 89  PRO C C   1 
ATOM 5940 O O   . PRO E 5 89  ? 360.460 355.731 442.926 1.00 126.26 ? 89  PRO C O   1 
ATOM 5941 C CB  . PRO E 5 89  ? 358.818 355.458 440.359 1.00 126.26 ? 89  PRO C CB  1 
ATOM 5942 C CG  . PRO E 5 89  ? 358.920 356.576 439.380 1.00 126.26 ? 89  PRO C CG  1 
ATOM 5943 C CD  . PRO E 5 89  ? 359.384 357.739 440.164 1.00 126.26 ? 89  PRO C CD  1 
ATOM 5944 N N   . GLY E 5 90  ? 358.543 354.835 443.717 1.00 125.11 ? 90  GLY C N   1 
ATOM 5945 C CA  . GLY E 5 90  ? 359.162 354.079 444.782 1.00 125.11 ? 90  GLY C CA  1 
ATOM 5946 C C   . GLY E 5 90  ? 359.624 354.877 445.979 1.00 125.11 ? 90  GLY C C   1 
ATOM 5947 O O   . GLY E 5 90  ? 359.891 354.285 447.031 1.00 125.11 ? 90  GLY C O   1 
ATOM 5948 N N   . ALA E 5 91  ? 359.721 356.201 445.868 1.00 134.12 ? 91  ALA C N   1 
ATOM 5949 C CA  . ALA E 5 91  ? 360.134 357.052 446.981 1.00 134.12 ? 91  ALA C CA  1 
ATOM 5950 C C   . ALA E 5 91  ? 358.913 357.291 447.863 1.00 134.12 ? 91  ALA C C   1 
ATOM 5951 O O   . ALA E 5 91  ? 358.230 358.308 447.752 1.00 134.12 ? 91  ALA C O   1 
ATOM 5952 C CB  . ALA E 5 91  ? 360.738 358.356 446.469 1.00 134.12 ? 91  ALA C CB  1 
ATOM 5953 N N   . ASN E 5 92  ? 358.590 356.257 448.661 1.00 131.50 ? 92  ASN C N   1 
ATOM 5954 C CA  . ASN E 5 92  ? 357.541 356.151 449.704 1.00 131.50 ? 92  ASN C CA  1 
ATOM 5955 C C   . ASN E 5 92  ? 356.183 356.756 449.301 1.00 131.50 ? 92  ASN C C   1 
ATOM 5956 O O   . ASN E 5 92  ? 355.361 357.107 450.155 1.00 131.50 ? 92  ASN C O   1 
ATOM 5957 C CB  . ASN E 5 92  ? 358.048 356.663 451.077 1.00 131.50 ? 92  ASN C CB  1 
ATOM 5958 C CG  . ASN E 5 92  ? 357.918 358.179 451.306 1.00 131.50 ? 92  ASN C CG  1 
ATOM 5959 O OD1 . ASN E 5 92  ? 357.963 358.992 450.396 1.00 131.50 ? 92  ASN C OD1 1 
ATOM 5960 N ND2 . ASN E 5 92  ? 357.742 358.545 452.569 1.00 131.50 ? 92  ASN C ND2 1 
ATOM 5961 N N   . ASN E 5 93  ? 355.886 356.782 448.005 1.00 120.61 ? 93  ASN C N   1 
ATOM 5962 C CA  . ASN E 5 93  ? 354.660 357.376 447.509 1.00 120.61 ? 93  ASN C CA  1 
ATOM 5963 C C   . ASN E 5 93  ? 353.487 356.413 447.684 1.00 120.61 ? 93  ASN C C   1 
ATOM 5964 O O   . ASN E 5 93  ? 353.617 355.314 448.230 1.00 120.61 ? 93  ASN C O   1 
ATOM 5965 C CB  . ASN E 5 93  ? 354.841 357.814 446.059 1.00 120.61 ? 93  ASN C CB  1 
ATOM 5966 C CG  . ASN E 5 93  ? 355.421 356.728 445.196 1.00 120.61 ? 93  ASN C CG  1 
ATOM 5967 O OD1 . ASN E 5 93  ? 355.698 355.629 445.665 1.00 120.61 ? 93  ASN C OD1 1 
ATOM 5968 N ND2 . ASN E 5 93  ? 355.600 357.023 443.920 1.00 120.61 ? 93  ASN C ND2 1 
ATOM 5969 N N   . VAL E 5 94  ? 352.320 356.838 447.205 1.00 110.43 ? 94  VAL C N   1 
ATOM 5970 C CA  . VAL E 5 94  ? 351.090 356.136 447.533 1.00 110.43 ? 94  VAL C CA  1 
ATOM 5971 C C   . VAL E 5 94  ? 350.780 355.035 446.529 1.00 110.43 ? 94  VAL C C   1 
ATOM 5972 O O   . VAL E 5 94  ? 349.965 354.152 446.807 1.00 110.43 ? 94  VAL C O   1 
ATOM 5973 C CB  . VAL E 5 94  ? 349.948 357.150 447.635 1.00 110.43 ? 94  VAL C CB  1 
ATOM 5974 C CG1 . VAL E 5 94  ? 350.203 358.076 448.793 1.00 110.43 ? 94  VAL C CG1 1 
ATOM 5975 C CG2 . VAL E 5 94  ? 349.859 357.938 446.362 1.00 110.43 ? 94  VAL C CG2 1 
ATOM 5976 N N   . LEU E 5 95  ? 351.417 355.054 445.361 1.00 107.65 ? 95  LEU C N   1 
ATOM 5977 C CA  . LEU E 5 95  ? 351.285 353.988 444.381 1.00 107.65 ? 95  LEU C CA  1 
ATOM 5978 C C   . LEU E 5 95  ? 352.274 352.858 444.618 1.00 107.65 ? 95  LEU C C   1 
ATOM 5979 O O   . LEU E 5 95  ? 352.495 352.041 443.721 1.00 107.65 ? 95  LEU C O   1 
ATOM 5980 C CB  . LEU E 5 95  ? 351.474 354.542 442.971 1.00 107.65 ? 95  LEU C CB  1 
ATOM 5981 C CG  . LEU E 5 95  ? 350.622 355.733 442.552 1.00 107.65 ? 95  LEU C CG  1 
ATOM 5982 C CD1 . LEU E 5 95  ? 351.144 356.305 441.261 1.00 107.65 ? 95  LEU C CD1 1 
ATOM 5983 C CD2 . LEU E 5 95  ? 349.192 355.301 442.382 1.00 107.65 ? 95  LEU C CD2 1 
ATOM 5984 N N   . ASN E 5 96  ? 352.882 352.801 445.798 1.00 108.94 ? 96  ASN C N   1 
ATOM 5985 C CA  . ASN E 5 96  ? 353.974 351.868 446.029 1.00 108.94 ? 96  ASN C CA  1 
ATOM 5986 C C   . ASN E 5 96  ? 353.460 350.462 446.301 1.00 108.94 ? 96  ASN C C   1 
ATOM 5987 O O   . ASN E 5 96  ? 353.849 349.512 445.617 1.00 108.94 ? 96  ASN C O   1 
ATOM 5988 C CB  . ASN E 5 96  ? 354.829 352.359 447.192 1.00 108.94 ? 96  ASN C CB  1 
ATOM 5989 C CG  . ASN E 5 96  ? 356.219 351.798 447.158 1.00 108.94 ? 96  ASN C CG  1 
ATOM 5990 O OD1 . ASN E 5 96  ? 356.581 351.074 446.235 1.00 108.94 ? 96  ASN C OD1 1 
ATOM 5991 N ND2 . ASN E 5 96  ? 357.015 352.126 448.166 1.00 108.94 ? 96  ASN C ND2 1 
ATOM 5992 N N   . ARG E 5 97  ? 352.585 350.310 447.291 1.00 103.16 ? 97  ARG C N   1 
ATOM 5993 C CA  . ARG E 5 97  ? 352.127 349.002 447.732 1.00 103.16 ? 97  ARG C CA  1 
ATOM 5994 C C   . ARG E 5 97  ? 350.884 348.524 447.004 1.00 103.16 ? 97  ARG C C   1 
ATOM 5995 O O   . ARG E 5 97  ? 350.343 347.476 447.359 1.00 103.16 ? 97  ARG C O   1 
ATOM 5996 C CB  . ARG E 5 97  ? 351.855 349.010 449.235 1.00 103.16 ? 97  ARG C CB  1 
ATOM 5997 C CG  . ARG E 5 97  ? 352.975 349.569 450.077 1.00 103.16 ? 97  ARG C CG  1 
ATOM 5998 C CD  . ARG E 5 97  ? 354.272 348.833 449.831 1.00 103.16 ? 97  ARG C CD  1 
ATOM 5999 N NE  . ARG E 5 97  ? 354.143 347.395 450.017 1.00 103.16 ? 97  ARG C NE  1 
ATOM 6000 C CZ  . ARG E 5 97  ? 354.383 346.773 451.163 1.00 103.16 ? 97  ARG C CZ  1 
ATOM 6001 N NH1 . ARG E 5 97  ? 354.758 347.466 452.228 1.00 103.16 ? 97  ARG C NH1 1 
ATOM 6002 N NH2 . ARG E 5 97  ? 354.248 345.459 451.243 1.00 103.16 ? 97  ARG C NH2 1 
ATOM 6003 N N   . THR E 5 98  ? 350.416 349.253 445.997 1.00 103.94 ? 98  THR C N   1 
ATOM 6004 C CA  . THR E 5 98  ? 349.226 348.829 445.279 1.00 103.94 ? 98  THR C CA  1 
ATOM 6005 C C   . THR E 5 98  ? 349.555 347.665 444.352 1.00 103.94 ? 98  THR C C   1 
ATOM 6006 O O   . THR E 5 98  ? 350.701 347.229 444.243 1.00 103.94 ? 98  THR C O   1 
ATOM 6007 C CB  . THR E 5 98  ? 348.629 349.987 444.492 1.00 103.94 ? 98  THR C CB  1 
ATOM 6008 O OG1 . THR E 5 98  ? 347.437 349.543 443.841 1.00 103.94 ? 98  THR C OG1 1 
ATOM 6009 C CG2 . THR E 5 98  ? 349.596 350.463 443.448 1.00 103.94 ? 98  THR C CG2 1 
ATOM 6010 N N   . LEU E 5 99  ? 348.532 347.157 443.662 1.00 99.64  ? 99  LEU C N   1 
ATOM 6011 C CA  . LEU E 5 99  ? 348.715 345.999 442.794 1.00 99.64  ? 99  LEU C CA  1 
ATOM 6012 C C   . LEU E 5 99  ? 349.552 346.323 441.569 1.00 99.64  ? 99  LEU C C   1 
ATOM 6013 O O   . LEU E 5 99  ? 350.181 345.424 441.008 1.00 99.64  ? 99  LEU C O   1 
ATOM 6014 C CB  . LEU E 5 99  ? 347.356 345.454 442.373 1.00 99.64  ? 99  LEU C CB  1 
ATOM 6015 C CG  . LEU E 5 99  ? 347.247 344.047 441.808 1.00 99.64  ? 99  LEU C CG  1 
ATOM 6016 C CD1 . LEU E 5 99  ? 348.126 343.107 442.588 1.00 99.64  ? 99  LEU C CD1 1 
ATOM 6017 C CD2 . LEU E 5 99  ? 345.810 343.597 441.886 1.00 99.64  ? 99  LEU C CD2 1 
ATOM 6018 N N   . LEU E 5 100 ? 349.585 347.584 441.154 1.00 101.41 ? 100 LEU C N   1 
ATOM 6019 C CA  . LEU E 5 100 ? 350.501 347.994 440.101 1.00 101.41 ? 100 LEU C CA  1 
ATOM 6020 C C   . LEU E 5 100 ? 351.926 348.095 440.619 1.00 101.41 ? 100 LEU C C   1 
ATOM 6021 O O   . LEU E 5 100 ? 352.850 347.556 440.007 1.00 101.41 ? 100 LEU C O   1 
ATOM 6022 C CB  . LEU E 5 100 ? 350.055 349.328 439.518 1.00 101.41 ? 100 LEU C CB  1 
ATOM 6023 C CG  . LEU E 5 100 ? 351.001 349.956 438.512 1.00 101.41 ? 100 LEU C CG  1 
ATOM 6024 C CD1 . LEU E 5 100 ? 351.048 349.103 437.270 1.00 101.41 ? 100 LEU C CD1 1 
ATOM 6025 C CD2 . LEU E 5 100 ? 350.520 351.340 438.188 1.00 101.41 ? 100 LEU C CD2 1 
ATOM 6026 N N   . GLY E 5 101 ? 352.123 348.765 441.750 1.00 103.43 ? 101 GLY C N   1 
ATOM 6027 C CA  . GLY E 5 101 ? 353.452 348.936 442.300 1.00 103.43 ? 101 GLY C CA  1 
ATOM 6028 C C   . GLY E 5 101 ? 354.020 347.712 442.980 1.00 103.43 ? 101 GLY C C   1 
ATOM 6029 O O   . GLY E 5 101 ? 355.181 347.746 443.395 1.00 103.43 ? 101 GLY C O   1 
ATOM 6030 N N   . GLU E 5 102 ? 353.239 346.645 443.118 1.00 110.41 ? 102 GLU C N   1 
ATOM 6031 C CA  . GLU E 5 102 ? 353.753 345.406 443.676 1.00 110.41 ? 102 GLU C CA  1 
ATOM 6032 C C   . GLU E 5 102 ? 354.416 344.526 442.634 1.00 110.41 ? 102 GLU C C   1 
ATOM 6033 O O   . GLU E 5 102 ? 355.299 343.738 442.983 1.00 110.41 ? 102 GLU C O   1 
ATOM 6034 C CB  . GLU E 5 102 ? 352.633 344.609 444.346 1.00 110.41 ? 102 GLU C CB  1 
ATOM 6035 C CG  . GLU E 5 102 ? 352.492 344.818 445.849 1.00 110.41 ? 102 GLU C CG  1 
ATOM 6036 C CD  . GLU E 5 102 ? 353.581 344.160 446.689 1.00 110.41 ? 102 GLU C CD  1 
ATOM 6037 O OE1 . GLU E 5 102 ? 354.454 343.450 446.146 1.00 110.41 ? 102 GLU C OE1 1 
ATOM 6038 O OE2 . GLU E 5 102 ? 353.556 344.352 447.923 1.00 110.41 ? 102 GLU C OE2 1 
ATOM 6039 N N   . ILE E 5 103 ? 354.006 344.628 441.373 1.00 105.46 ? 103 ILE C N   1 
ATOM 6040 C CA  . ILE E 5 103 ? 354.656 343.854 440.327 1.00 105.46 ? 103 ILE C CA  1 
ATOM 6041 C C   . ILE E 5 103 ? 355.857 344.602 439.778 1.00 105.46 ? 103 ILE C C   1 
ATOM 6042 O O   . ILE E 5 103 ? 356.884 343.999 439.459 1.00 105.46 ? 103 ILE C O   1 
ATOM 6043 C CB  . ILE E 5 103 ? 353.653 343.515 439.217 1.00 105.46 ? 103 ILE C CB  1 
ATOM 6044 C CG1 . ILE E 5 103 ? 352.326 343.094 439.820 1.00 105.46 ? 103 ILE C CG1 1 
ATOM 6045 C CG2 . ILE E 5 103 ? 354.184 342.403 438.348 1.00 105.46 ? 103 ILE C CG2 1 
ATOM 6046 C CD1 . ILE E 5 103 ? 351.278 342.849 438.788 1.00 105.46 ? 103 ILE C CD1 1 
ATOM 6047 N N   . LEU E 5 104 ? 355.763 345.921 439.679 1.00 106.54 ? 104 LEU C N   1 
ATOM 6048 C CA  . LEU E 5 104 ? 356.843 346.711 439.110 1.00 106.54 ? 104 LEU C CA  1 
ATOM 6049 C C   . LEU E 5 104 ? 358.040 346.846 440.034 1.00 106.54 ? 104 LEU C C   1 
ATOM 6050 O O   . LEU E 5 104 ? 359.073 347.365 439.603 1.00 106.54 ? 104 LEU C O   1 
ATOM 6051 C CB  . LEU E 5 104 ? 356.337 348.097 438.726 1.00 106.54 ? 104 LEU C CB  1 
ATOM 6052 C CG  . LEU E 5 104 ? 355.209 348.138 437.705 1.00 106.54 ? 104 LEU C CG  1 
ATOM 6053 C CD1 . LEU E 5 104 ? 355.026 349.550 437.223 1.00 106.54 ? 104 LEU C CD1 1 
ATOM 6054 C CD2 . LEU E 5 104 ? 355.475 347.212 436.540 1.00 106.54 ? 104 LEU C CD2 1 
ATOM 6055 N N   . ASN E 5 105 ? 357.938 346.407 441.283 1.00 112.61 ? 105 ASN C N   1 
ATOM 6056 C CA  . ASN E 5 105 ? 359.093 346.336 442.159 1.00 112.61 ? 105 ASN C CA  1 
ATOM 6057 C C   . ASN E 5 105 ? 359.855 345.033 442.011 1.00 112.61 ? 105 ASN C C   1 
ATOM 6058 O O   . ASN E 5 105 ? 360.833 344.820 442.729 1.00 112.61 ? 105 ASN C O   1 
ATOM 6059 C CB  . ASN E 5 105 ? 358.676 346.525 443.613 1.00 112.61 ? 105 ASN C CB  1 
ATOM 6060 C CG  . ASN E 5 105 ? 358.621 347.975 444.004 1.00 112.61 ? 105 ASN C CG  1 
ATOM 6061 O OD1 . ASN E 5 105 ? 358.208 348.823 443.218 1.00 112.61 ? 105 ASN C OD1 1 
ATOM 6062 N ND2 . ASN E 5 105 ? 359.064 348.278 445.212 1.00 112.61 ? 105 ASN C ND2 1 
ATOM 6063 N N   . TYR E 5 106 ? 359.430 344.156 441.109 1.00 114.20 ? 106 TYR C N   1 
ATOM 6064 C CA  . TYR E 5 106 ? 360.207 342.985 440.748 1.00 114.20 ? 106 TYR C CA  1 
ATOM 6065 C C   . TYR E 5 106 ? 361.129 343.247 439.568 1.00 114.20 ? 106 TYR C C   1 
ATOM 6066 O O   . TYR E 5 106 ? 362.048 342.460 439.330 1.00 114.20 ? 106 TYR C O   1 
ATOM 6067 C CB  . TYR E 5 106 ? 359.283 341.814 440.427 1.00 114.20 ? 106 TYR C CB  1 
ATOM 6068 C CG  . TYR E 5 106 ? 358.731 341.120 441.642 1.00 114.20 ? 106 TYR C CG  1 
ATOM 6069 C CD1 . TYR E 5 106 ? 359.496 340.207 442.348 1.00 114.20 ? 106 TYR C CD1 1 
ATOM 6070 C CD2 . TYR E 5 106 ? 357.443 341.372 442.079 1.00 114.20 ? 106 TYR C CD2 1 
ATOM 6071 C CE1 . TYR E 5 106 ? 358.995 339.569 443.459 1.00 114.20 ? 106 TYR C CE1 1 
ATOM 6072 C CE2 . TYR E 5 106 ? 356.932 340.740 443.187 1.00 114.20 ? 106 TYR C CE2 1 
ATOM 6073 C CZ  . TYR E 5 106 ? 357.712 339.841 443.871 1.00 114.20 ? 106 TYR C CZ  1 
ATOM 6074 O OH  . TYR E 5 106 ? 357.204 339.211 444.978 1.00 114.20 ? 106 TYR C OH  1 
ATOM 6075 N N   . TYR E 5 107 ? 360.912 344.335 438.834 1.00 115.96 ? 107 TYR C N   1 
ATOM 6076 C CA  . TYR E 5 107 ? 361.705 344.666 437.663 1.00 115.96 ? 107 TYR C CA  1 
ATOM 6077 C C   . TYR E 5 107 ? 362.341 346.030 437.871 1.00 115.96 ? 107 TYR C C   1 
ATOM 6078 O O   . TYR E 5 107 ? 361.808 346.879 438.587 1.00 115.96 ? 107 TYR C O   1 
ATOM 6079 C CB  . TYR E 5 107 ? 360.849 344.666 436.401 1.00 115.96 ? 107 TYR C CB  1 
ATOM 6080 C CG  . TYR E 5 107 ? 360.133 343.370 436.152 1.00 115.96 ? 107 TYR C CG  1 
ATOM 6081 C CD1 . TYR E 5 107 ? 360.782 342.308 435.547 1.00 115.96 ? 107 TYR C CD1 1 
ATOM 6082 C CD2 . TYR E 5 107 ? 358.807 343.208 436.513 1.00 115.96 ? 107 TYR C CD2 1 
ATOM 6083 C CE1 . TYR E 5 107 ? 360.133 341.117 435.311 1.00 115.96 ? 107 TYR C CE1 1 
ATOM 6084 C CE2 . TYR E 5 107 ? 358.148 342.020 436.283 1.00 115.96 ? 107 TYR C CE2 1 
ATOM 6085 C CZ  . TYR E 5 107 ? 358.818 340.980 435.682 1.00 115.96 ? 107 TYR C CZ  1 
ATOM 6086 O OH  . TYR E 5 107 ? 358.173 339.794 435.446 1.00 115.96 ? 107 TYR C OH  1 
ATOM 6087 N N   . THR E 5 108 ? 363.485 346.251 437.229 1.00 117.97 ? 108 THR C N   1 
ATOM 6088 C CA  . THR E 5 108 ? 364.218 347.502 437.389 1.00 117.97 ? 108 THR C CA  1 
ATOM 6089 C C   . THR E 5 108 ? 363.999 348.492 436.260 1.00 117.97 ? 108 THR C C   1 
ATOM 6090 O O   . THR E 5 108 ? 364.234 349.685 436.447 1.00 117.97 ? 108 THR C O   1 
ATOM 6091 C CB  . THR E 5 108 ? 365.716 347.233 437.514 1.00 117.97 ? 108 THR C CB  1 
ATOM 6092 O OG1 . THR E 5 108 ? 366.242 346.900 436.228 1.00 117.97 ? 108 THR C OG1 1 
ATOM 6093 C CG2 . THR E 5 108 ? 365.967 346.092 438.454 1.00 117.97 ? 108 THR C CG2 1 
ATOM 6094 N N   . HIS E 5 109 ? 363.563 348.040 435.089 1.00 121.43 ? 109 HIS C N   1 
ATOM 6095 C CA  . HIS E 5 109 ? 363.315 348.924 433.958 1.00 121.43 ? 109 HIS C CA  1 
ATOM 6096 C C   . HIS E 5 109 ? 361.881 348.735 433.502 1.00 121.43 ? 109 HIS C C   1 
ATOM 6097 O O   . HIS E 5 109 ? 361.500 347.627 433.121 1.00 121.43 ? 109 HIS C O   1 
ATOM 6098 C CB  . HIS E 5 109 ? 364.272 348.626 432.805 1.00 121.43 ? 109 HIS C CB  1 
ATOM 6099 C CG  . HIS E 5 109 ? 365.705 348.910 433.121 1.00 121.43 ? 109 HIS C CG  1 
ATOM 6100 N ND1 . HIS E 5 109 ? 366.736 348.109 432.680 1.00 121.43 ? 109 HIS C ND1 1 
ATOM 6101 C CD2 . HIS E 5 109 ? 366.281 349.910 433.828 1.00 121.43 ? 109 HIS C CD2 1 
ATOM 6102 C CE1 . HIS E 5 109 ? 367.885 348.600 433.105 1.00 121.43 ? 109 HIS C CE1 1 
ATOM 6103 N NE2 . HIS E 5 109 ? 367.637 349.694 433.804 1.00 121.43 ? 109 HIS C NE2 1 
ATOM 6104 N N   . TRP E 5 110 ? 361.093 349.808 433.526 1.00 116.44 ? 110 TRP C N   1 
ATOM 6105 C CA  . TRP E 5 110 ? 359.720 349.727 433.050 1.00 116.44 ? 110 TRP C CA  1 
ATOM 6106 C C   . TRP E 5 110 ? 359.280 351.080 432.512 1.00 116.44 ? 110 TRP C C   1 
ATOM 6107 O O   . TRP E 5 110 ? 359.818 352.125 432.881 1.00 116.44 ? 110 TRP C O   1 
ATOM 6108 C CB  . TRP E 5 110 ? 358.769 349.239 434.146 1.00 116.44 ? 110 TRP C CB  1 
ATOM 6109 C CG  . TRP E 5 110 ? 359.101 349.731 435.499 1.00 116.44 ? 110 TRP C CG  1 
ATOM 6110 C CD1 . TRP E 5 110 ? 359.869 349.107 436.431 1.00 116.44 ? 110 TRP C CD1 1 
ATOM 6111 C CD2 . TRP E 5 110 ? 358.665 350.951 436.092 1.00 116.44 ? 110 TRP C CD2 1 
ATOM 6112 N NE1 . TRP E 5 110 ? 359.945 349.866 437.568 1.00 116.44 ? 110 TRP C NE1 1 
ATOM 6113 C CE2 . TRP E 5 110 ? 359.212 351.006 437.383 1.00 116.44 ? 110 TRP C CE2 1 
ATOM 6114 C CE3 . TRP E 5 110 ? 357.867 352.005 435.654 1.00 116.44 ? 110 TRP C CE3 1 
ATOM 6115 C CZ2 . TRP E 5 110 ? 358.989 352.069 438.235 1.00 116.44 ? 110 TRP C CZ2 1 
ATOM 6116 C CZ3 . TRP E 5 110 ? 357.648 353.056 436.501 1.00 116.44 ? 110 TRP C CZ3 1 
ATOM 6117 C CH2 . TRP E 5 110 ? 358.205 353.082 437.776 1.00 116.44 ? 110 TRP C CH2 1 
ATOM 6118 N N   . SER E 5 111 ? 358.279 351.042 431.633 1.00 119.96 ? 111 SER C N   1 
ATOM 6119 C CA  . SER E 5 111 ? 357.829 352.228 430.921 1.00 119.96 ? 111 SER C CA  1 
ATOM 6120 C C   . SER E 5 111 ? 356.416 352.006 430.406 1.00 119.96 ? 111 SER C C   1 
ATOM 6121 O O   . SER E 5 111 ? 356.129 350.968 429.808 1.00 119.96 ? 111 SER C O   1 
ATOM 6122 C CB  . SER E 5 111 ? 358.751 352.538 429.746 1.00 119.96 ? 111 SER C CB  1 
ATOM 6123 O OG  . SER E 5 111 ? 358.296 351.871 428.584 1.00 119.96 ? 111 SER C OG  1 
ATOM 6124 N N   . GLY E 5 112 ? 355.550 352.986 430.622 1.00 117.45 ? 112 GLY C N   1 
ATOM 6125 C CA  . GLY E 5 112 ? 354.197 352.897 430.111 1.00 117.45 ? 112 GLY C CA  1 
ATOM 6126 C C   . GLY E 5 112 ? 353.366 354.069 430.573 1.00 117.45 ? 112 GLY C C   1 
ATOM 6127 O O   . GLY E 5 112 ? 353.897 355.062 431.070 1.00 117.45 ? 112 GLY C O   1 
ATOM 6128 N N   . SER E 5 113 ? 352.054 353.946 430.409 1.00 115.07 ? 113 SER C N   1 
ATOM 6129 C CA  . SER E 5 113 ? 351.111 354.950 430.874 1.00 115.07 ? 113 SER C CA  1 
ATOM 6130 C C   . SER E 5 113 ? 350.178 354.341 431.915 1.00 115.07 ? 113 SER C C   1 
ATOM 6131 O O   . SER E 5 113 ? 350.250 353.152 432.227 1.00 115.07 ? 113 SER C O   1 
ATOM 6132 C CB  . SER E 5 113 ? 350.315 355.541 429.711 1.00 115.07 ? 113 SER C CB  1 
ATOM 6133 O OG  . SER E 5 113 ? 349.174 354.757 429.438 1.00 115.07 ? 113 SER C OG  1 
ATOM 6134 N N   . ILE E 5 114 ? 349.294 355.171 432.462 1.00 110.60 ? 114 ILE C N   1 
ATOM 6135 C CA  . ILE E 5 114 ? 348.513 354.818 433.644 1.00 110.60 ? 114 ILE C CA  1 
ATOM 6136 C C   . ILE E 5 114 ? 347.109 355.394 433.516 1.00 110.60 ? 114 ILE C C   1 
ATOM 6137 O O   . ILE E 5 114 ? 346.945 356.561 433.151 1.00 110.60 ? 114 ILE C O   1 
ATOM 6138 C CB  . ILE E 5 114 ? 349.207 355.326 434.926 1.00 110.60 ? 114 ILE C CB  1 
ATOM 6139 C CG1 . ILE E 5 114 ? 350.232 354.316 435.417 1.00 110.60 ? 114 ILE C CG1 1 
ATOM 6140 C CG2 . ILE E 5 114 ? 348.226 355.663 436.042 1.00 110.60 ? 114 ILE C CG2 1 
ATOM 6141 C CD1 . ILE E 5 114 ? 350.897 354.752 436.675 1.00 110.60 ? 114 ILE C CD1 1 
ATOM 6142 N N   . LYS E 5 115 ? 346.098 354.570 433.789 1.00 108.07 ? 115 LYS C N   1 
ATOM 6143 C CA  . LYS E 5 115 ? 344.746 355.055 434.023 1.00 108.07 ? 115 LYS C CA  1 
ATOM 6144 C C   . LYS E 5 115 ? 344.600 355.456 435.481 1.00 108.07 ? 115 LYS C C   1 
ATOM 6145 O O   . LYS E 5 115 ? 345.041 354.728 436.374 1.00 108.07 ? 115 LYS C O   1 
ATOM 6146 C CB  . LYS E 5 115 ? 343.713 353.985 433.682 1.00 108.07 ? 115 LYS C CB  1 
ATOM 6147 C CG  . LYS E 5 115 ? 343.426 353.845 432.207 1.00 108.07 ? 115 LYS C CG  1 
ATOM 6148 C CD  . LYS E 5 115 ? 341.967 353.506 431.960 1.00 108.07 ? 115 LYS C CD  1 
ATOM 6149 C CE  . LYS E 5 115 ? 341.524 352.304 432.776 1.00 108.07 ? 115 LYS C CE  1 
ATOM 6150 N NZ  . LYS E 5 115 ? 340.093 351.983 432.541 1.00 108.07 ? 115 LYS C NZ  1 
ATOM 6151 N N   . LEU E 5 116 ? 343.976 356.602 435.723 1.00 100.53 ? 116 LEU C N   1 
ATOM 6152 C CA  . LEU E 5 116 ? 343.701 357.081 437.075 1.00 100.53 ? 116 LEU C CA  1 
ATOM 6153 C C   . LEU E 5 116 ? 342.202 357.319 437.188 1.00 100.53 ? 116 LEU C C   1 
ATOM 6154 O O   . LEU E 5 116 ? 341.714 358.396 436.838 1.00 100.53 ? 116 LEU C O   1 
ATOM 6155 C CB  . LEU E 5 116 ? 344.482 358.349 437.380 1.00 100.53 ? 116 LEU C CB  1 
ATOM 6156 C CG  . LEU E 5 116 ? 345.855 358.164 438.011 1.00 100.53 ? 116 LEU C CG  1 
ATOM 6157 C CD1 . LEU E 5 116 ? 346.633 359.453 437.932 1.00 100.53 ? 116 LEU C CD1 1 
ATOM 6158 C CD2 . LEU E 5 116 ? 345.714 357.719 439.448 1.00 100.53 ? 116 LEU C CD2 1 
ATOM 6159 N N   . THR E 5 117 ? 341.473 356.325 437.676 1.00 99.41  ? 117 THR C N   1 
ATOM 6160 C CA  . THR E 5 117 ? 340.025 356.413 437.784 1.00 99.41  ? 117 THR C CA  1 
ATOM 6161 C C   . THR E 5 117 ? 339.651 356.978 439.144 1.00 99.41  ? 117 THR C C   1 
ATOM 6162 O O   . THR E 5 117 ? 340.143 356.507 440.172 1.00 99.41  ? 117 THR C O   1 
ATOM 6163 C CB  . THR E 5 117 ? 339.387 355.037 437.594 1.00 99.41  ? 117 THR C CB  1 
ATOM 6164 O OG1 . THR E 5 117 ? 339.807 354.480 436.345 1.00 99.41  ? 117 THR C OG1 1 
ATOM 6165 C CG2 . THR E 5 117 ? 337.879 355.145 437.594 1.00 99.41  ? 117 THR C CG2 1 
ATOM 6166 N N   . PHE E 5 118 ? 338.798 357.992 439.150 1.00 96.57  ? 118 PHE C N   1 
ATOM 6167 C CA  . PHE E 5 118 ? 338.258 358.545 440.380 1.00 96.57  ? 118 PHE C CA  1 
ATOM 6168 C C   . PHE E 5 118 ? 336.786 358.186 440.509 1.00 96.57  ? 118 PHE C C   1 
ATOM 6169 O O   . PHE E 5 118 ? 336.144 357.758 439.550 1.00 96.57  ? 118 PHE C O   1 
ATOM 6170 C CB  . PHE E 5 118 ? 338.429 360.060 440.418 1.00 96.57  ? 118 PHE C CB  1 
ATOM 6171 C CG  . PHE E 5 118 ? 339.849 360.502 440.513 1.00 96.57  ? 118 PHE C CG  1 
ATOM 6172 C CD1 . PHE E 5 118 ? 340.449 360.663 441.739 1.00 96.57  ? 118 PHE C CD1 1 
ATOM 6173 C CD2 . PHE E 5 118 ? 340.582 360.760 439.374 1.00 96.57  ? 118 PHE C CD2 1 
ATOM 6174 C CE1 . PHE E 5 118 ? 341.753 361.071 441.827 1.00 96.57  ? 118 PHE C CE1 1 
ATOM 6175 C CE2 . PHE E 5 118 ? 341.890 361.170 439.460 1.00 96.57  ? 118 PHE C CE2 1 
ATOM 6176 C CZ  . PHE E 5 118 ? 342.474 361.325 440.688 1.00 96.57  ? 118 PHE C CZ  1 
ATOM 6177 N N   . MET E 5 119 ? 336.254 358.367 441.714 1.00 102.80 ? 119 MET C N   1 
ATOM 6178 C CA  . MET E 5 119 ? 334.853 358.065 441.966 1.00 102.80 ? 119 MET C CA  1 
ATOM 6179 C C   . MET E 5 119 ? 334.372 358.891 443.144 1.00 102.80 ? 119 MET C C   1 
ATOM 6180 O O   . MET E 5 119 ? 335.063 358.978 444.161 1.00 102.80 ? 119 MET C O   1 
ATOM 6181 C CB  . MET E 5 119 ? 334.649 356.577 442.248 1.00 102.80 ? 119 MET C CB  1 
ATOM 6182 C CG  . MET E 5 119 ? 333.298 356.058 441.817 1.00 102.80 ? 119 MET C CG  1 
ATOM 6183 S SD  . MET E 5 119 ? 333.238 354.264 441.759 1.00 102.80 ? 119 MET C SD  1 
ATOM 6184 C CE  . MET E 5 119 ? 333.441 353.872 443.490 1.00 102.80 ? 119 MET C CE  1 
ATOM 6185 N N   . PHE E 5 120 ? 333.195 359.491 443.002 1.00 104.39 ? 120 PHE C N   1 
ATOM 6186 C CA  . PHE E 5 120 ? 332.596 360.310 444.051 1.00 104.39 ? 120 PHE C CA  1 
ATOM 6187 C C   . PHE E 5 120 ? 331.659 359.433 444.861 1.00 104.39 ? 120 PHE C C   1 
ATOM 6188 O O   . PHE E 5 120 ? 330.574 359.076 444.402 1.00 104.39 ? 120 PHE C O   1 
ATOM 6189 C CB  . PHE E 5 120 ? 331.855 361.493 443.449 1.00 104.39 ? 120 PHE C CB  1 
ATOM 6190 C CG  . PHE E 5 120 ? 331.339 362.461 444.462 1.00 104.39 ? 120 PHE C CG  1 
ATOM 6191 C CD1 . PHE E 5 120 ? 332.161 363.444 444.975 1.00 104.39 ? 120 PHE C CD1 1 
ATOM 6192 C CD2 . PHE E 5 120 ? 330.023 362.410 444.883 1.00 104.39 ? 120 PHE C CD2 1 
ATOM 6193 C CE1 . PHE E 5 120 ? 331.685 364.350 445.897 1.00 104.39 ? 120 PHE C CE1 1 
ATOM 6194 C CE2 . PHE E 5 120 ? 329.544 363.317 445.804 1.00 104.39 ? 120 PHE C CE2 1 
ATOM 6195 C CZ  . PHE E 5 120 ? 330.376 364.284 446.310 1.00 104.39 ? 120 PHE C CZ  1 
ATOM 6196 N N   . CYS E 5 121 ? 332.071 359.090 446.074 1.00 109.84 ? 121 CYS C N   1 
ATOM 6197 C CA  . CYS E 5 121 ? 331.285 358.209 446.926 1.00 109.84 ? 121 CYS C CA  1 
ATOM 6198 C C   . CYS E 5 121 ? 330.481 359.041 447.921 1.00 109.84 ? 121 CYS C C   1 
ATOM 6199 O O   . CYS E 5 121 ? 330.665 358.977 449.133 1.00 109.84 ? 121 CYS C O   1 
ATOM 6200 C CB  . CYS E 5 121 ? 332.198 357.218 447.627 1.00 109.84 ? 121 CYS C CB  1 
ATOM 6201 S SG  . CYS E 5 121 ? 332.693 355.866 446.565 1.00 109.84 ? 121 CYS C SG  1 
ATOM 6202 N N   . GLY E 5 122 ? 329.574 359.837 447.375 1.00 109.70 ? 122 GLY C N   1 
ATOM 6203 C CA  . GLY E 5 122 ? 328.765 360.712 448.194 1.00 109.70 ? 122 GLY C CA  1 
ATOM 6204 C C   . GLY E 5 122 ? 327.294 360.546 447.900 1.00 109.70 ? 122 GLY C C   1 
ATOM 6205 O O   . GLY E 5 122 ? 326.891 359.529 447.331 1.00 109.70 ? 122 GLY C O   1 
ATOM 6206 N N   . SER E 5 123 ? 326.482 361.531 448.268 1.00 106.57 ? 123 SER C N   1 
ATOM 6207 C CA  . SER E 5 123 ? 325.050 361.427 448.058 1.00 106.57 ? 123 SER C CA  1 
ATOM 6208 C C   . SER E 5 123 ? 324.691 361.699 446.602 1.00 106.57 ? 123 SER C C   1 
ATOM 6209 O O   . SER E 5 123 ? 325.538 362.039 445.773 1.00 106.57 ? 123 SER C O   1 
ATOM 6210 C CB  . SER E 5 123 ? 324.303 362.397 448.961 1.00 106.57 ? 123 SER C CB  1 
ATOM 6211 O OG  . SER E 5 123 ? 323.026 362.670 448.422 1.00 106.57 ? 123 SER C OG  1 
ATOM 6212 N N   . ALA E 5 124 ? 323.408 361.537 446.292 1.00 110.46 ? 124 ALA C N   1 
ATOM 6213 C CA  . ALA E 5 124 ? 322.897 361.833 444.962 1.00 110.46 ? 124 ALA C CA  1 
ATOM 6214 C C   . ALA E 5 124 ? 322.305 363.227 444.856 1.00 110.46 ? 124 ALA C C   1 
ATOM 6215 O O   . ALA E 5 124 ? 321.953 363.651 443.752 1.00 110.46 ? 124 ALA C O   1 
ATOM 6216 C CB  . ALA E 5 124 ? 321.839 360.808 444.553 1.00 110.46 ? 124 ALA C CB  1 
ATOM 6217 N N   . MET E 5 125 ? 322.183 363.942 445.971 1.00 111.51 ? 125 MET C N   1 
ATOM 6218 C CA  . MET E 5 125 ? 321.651 365.295 445.988 1.00 111.51 ? 125 MET C CA  1 
ATOM 6219 C C   . MET E 5 125 ? 322.739 366.359 446.002 1.00 111.51 ? 125 MET C C   1 
ATOM 6220 O O   . MET E 5 125 ? 322.424 367.546 445.891 1.00 111.51 ? 125 MET C O   1 
ATOM 6221 C CB  . MET E 5 125 ? 320.736 365.481 447.200 1.00 111.51 ? 125 MET C CB  1 
ATOM 6222 C CG  . MET E 5 125 ? 319.480 364.647 447.149 1.00 111.51 ? 125 MET C CG  1 
ATOM 6223 S SD  . MET E 5 125 ? 318.347 365.258 445.901 1.00 111.51 ? 125 MET C SD  1 
ATOM 6224 C CE  . MET E 5 125 ? 317.432 363.773 445.530 1.00 111.51 ? 125 MET C CE  1 
ATOM 6225 N N   . ALA E 5 126 ? 324.000 365.969 446.129 1.00 109.57 ? 126 ALA C N   1 
ATOM 6226 C CA  . ALA E 5 126 ? 325.098 366.914 446.251 1.00 109.57 ? 126 ALA C CA  1 
ATOM 6227 C C   . ALA E 5 126 ? 325.750 367.145 444.898 1.00 109.57 ? 126 ALA C C   1 
ATOM 6228 O O   . ALA E 5 126 ? 325.985 366.199 444.144 1.00 109.57 ? 126 ALA C O   1 
ATOM 6229 C CB  . ALA E 5 126 ? 326.138 366.408 447.248 1.00 109.57 ? 126 ALA C CB  1 
ATOM 6230 N N   . THR E 5 127 ? 326.032 368.411 444.592 1.00 109.87 ? 127 THR C N   1 
ATOM 6231 C CA  . THR E 5 127 ? 326.705 368.796 443.361 1.00 109.87 ? 127 THR C CA  1 
ATOM 6232 C C   . THR E 5 127 ? 327.997 369.527 443.694 1.00 109.87 ? 127 THR C C   1 
ATOM 6233 O O   . THR E 5 127 ? 328.266 369.864 444.848 1.00 109.87 ? 127 THR C O   1 
ATOM 6234 C CB  . THR E 5 127 ? 325.842 369.704 442.478 1.00 109.87 ? 127 THR C CB  1 
ATOM 6235 O OG1 . THR E 5 127 ? 325.924 371.047 442.962 1.00 109.87 ? 127 THR C OG1 1 
ATOM 6236 C CG2 . THR E 5 127 ? 324.392 369.265 442.486 1.00 109.87 ? 127 THR C CG2 1 
ATOM 6237 N N   . GLY E 5 128 ? 328.789 369.781 442.661 1.00 109.46 ? 128 GLY C N   1 
ATOM 6238 C CA  . GLY E 5 128 ? 330.047 370.479 442.833 1.00 109.46 ? 128 GLY C CA  1 
ATOM 6239 C C   . GLY E 5 128 ? 330.870 370.406 441.567 1.00 109.46 ? 128 GLY C C   1 
ATOM 6240 O O   . GLY E 5 128 ? 330.459 369.827 440.560 1.00 109.46 ? 128 GLY C O   1 
ATOM 6241 N N   . LYS E 5 129 ? 332.052 371.009 441.638 1.00 107.65 ? 129 LYS C N   1 
ATOM 6242 C CA  . LYS E 5 129 ? 332.973 371.019 440.514 1.00 107.65 ? 129 LYS C CA  1 
ATOM 6243 C C   . LYS E 5 129 ? 334.397 370.910 441.031 1.00 107.65 ? 129 LYS C C   1 
ATOM 6244 O O   . LYS E 5 129 ? 334.737 371.511 442.052 1.00 107.65 ? 129 LYS C O   1 
ATOM 6245 C CB  . LYS E 5 129 ? 332.819 372.290 439.681 1.00 107.65 ? 129 LYS C CB  1 
ATOM 6246 C CG  . LYS E 5 129 ? 331.750 372.226 438.617 1.00 107.65 ? 129 LYS C CG  1 
ATOM 6247 C CD  . LYS E 5 129 ? 331.588 373.576 437.953 1.00 107.65 ? 129 LYS C CD  1 
ATOM 6248 C CE  . LYS E 5 129 ? 330.591 373.521 436.821 1.00 107.65 ? 129 LYS C CE  1 
ATOM 6249 N NZ  . LYS E 5 129 ? 331.074 372.685 435.692 1.00 107.65 ? 129 LYS C NZ  1 
ATOM 6250 N N   . PHE E 5 130 ? 335.227 370.148 440.324 1.00 104.34 ? 130 PHE C N   1 
ATOM 6251 C CA  . PHE E 5 130 ? 336.608 369.924 440.722 1.00 104.34 ? 130 PHE C CA  1 
ATOM 6252 C C   . PHE E 5 130 ? 337.535 370.068 439.527 1.00 104.34 ? 130 PHE C C   1 
ATOM 6253 O O   . PHE E 5 130 ? 337.165 369.757 438.394 1.00 104.34 ? 130 PHE C O   1 
ATOM 6254 C CB  . PHE E 5 130 ? 336.803 368.537 441.325 1.00 104.34 ? 130 PHE C CB  1 
ATOM 6255 C CG  . PHE E 5 130 ? 336.141 368.354 442.646 1.00 104.34 ? 130 PHE C CG  1 
ATOM 6256 C CD1 . PHE E 5 130 ? 336.563 369.065 443.745 1.00 104.34 ? 130 PHE C CD1 1 
ATOM 6257 C CD2 . PHE E 5 130 ? 335.101 367.462 442.790 1.00 104.34 ? 130 PHE C CD2 1 
ATOM 6258 C CE1 . PHE E 5 130 ? 335.955 368.894 444.964 1.00 104.34 ? 130 PHE C CE1 1 
ATOM 6259 C CE2 . PHE E 5 130 ? 334.491 367.286 444.006 1.00 104.34 ? 130 PHE C CE2 1 
ATOM 6260 C CZ  . PHE E 5 130 ? 334.917 368.003 445.093 1.00 104.34 ? 130 PHE C CZ  1 
ATOM 6261 N N   . LEU E 5 131 ? 338.748 370.537 439.797 1.00 107.20 ? 131 LEU C N   1 
ATOM 6262 C CA  . LEU E 5 131 ? 339.835 370.529 438.832 1.00 107.20 ? 131 LEU C CA  1 
ATOM 6263 C C   . LEU E 5 131 ? 340.716 369.316 439.080 1.00 107.20 ? 131 LEU C C   1 
ATOM 6264 O O   . LEU E 5 131 ? 340.879 368.881 440.221 1.00 107.20 ? 131 LEU C O   1 
ATOM 6265 C CB  . LEU E 5 131 ? 340.686 371.790 438.941 1.00 107.20 ? 131 LEU C CB  1 
ATOM 6266 C CG  . LEU E 5 131 ? 340.159 373.080 438.340 1.00 107.20 ? 131 LEU C CG  1 
ATOM 6267 C CD1 . LEU E 5 131 ? 341.244 374.114 438.394 1.00 107.20 ? 131 LEU C CD1 1 
ATOM 6268 C CD2 . LEU E 5 131 ? 339.726 372.854 436.920 1.00 107.20 ? 131 LEU C CD2 1 
ATOM 6269 N N   . LEU E 5 132 ? 341.294 368.775 438.012 1.00 105.47 ? 132 LEU C N   1 
ATOM 6270 C CA  . LEU E 5 132 ? 342.255 367.679 438.111 1.00 105.47 ? 132 LEU C CA  1 
ATOM 6271 C C   . LEU E 5 132 ? 343.470 368.080 437.287 1.00 105.47 ? 132 LEU C C   1 
ATOM 6272 O O   . LEU E 5 132 ? 343.580 367.725 436.114 1.00 105.47 ? 132 LEU C O   1 
ATOM 6273 C CB  . LEU E 5 132 ? 341.654 366.373 437.636 1.00 105.47 ? 132 LEU C CB  1 
ATOM 6274 C CG  . LEU E 5 132 ? 340.593 365.790 438.560 1.00 105.47 ? 132 LEU C CG  1 
ATOM 6275 C CD1 . LEU E 5 132 ? 339.870 364.656 437.882 1.00 105.47 ? 132 LEU C CD1 1 
ATOM 6276 C CD2 . LEU E 5 132 ? 341.244 365.310 439.828 1.00 105.47 ? 132 LEU C CD2 1 
ATOM 6277 N N   . ALA E 5 133 ? 344.382 368.817 437.902 1.00 108.26 ? 133 ALA C N   1 
ATOM 6278 C CA  . ALA E 5 133 ? 345.539 369.328 437.192 1.00 108.26 ? 133 ALA C CA  1 
ATOM 6279 C C   . ALA E 5 133 ? 346.675 368.322 437.234 1.00 108.26 ? 133 ALA C C   1 
ATOM 6280 O O   . ALA E 5 133 ? 346.924 367.680 438.255 1.00 108.26 ? 133 ALA C O   1 
ATOM 6281 C CB  . ALA E 5 133 ? 345.999 370.655 437.791 1.00 108.26 ? 133 ALA C CB  1 
ATOM 6282 N N   . TYR E 5 134 ? 347.368 368.192 436.108 1.00 115.05 ? 134 TYR C N   1 
ATOM 6283 C CA  . TYR E 5 134 ? 348.514 367.302 435.994 1.00 115.05 ? 134 TYR C CA  1 
ATOM 6284 C C   . TYR E 5 134 ? 349.719 368.123 435.571 1.00 115.05 ? 134 TYR C C   1 
ATOM 6285 O O   . TYR E 5 134 ? 349.702 368.747 434.509 1.00 115.05 ? 134 TYR C O   1 
ATOM 6286 C CB  . TYR E 5 134 ? 348.246 366.177 434.993 1.00 115.05 ? 134 TYR C CB  1 
ATOM 6287 C CG  . TYR E 5 134 ? 349.493 365.555 434.414 1.00 115.05 ? 134 TYR C CG  1 
ATOM 6288 C CD1 . TYR E 5 134 ? 350.382 364.853 435.214 1.00 115.05 ? 134 TYR C CD1 1 
ATOM 6289 C CD2 . TYR E 5 134 ? 349.773 365.660 433.062 1.00 115.05 ? 134 TYR C CD2 1 
ATOM 6290 C CE1 . TYR E 5 134 ? 351.519 364.291 434.686 1.00 115.05 ? 134 TYR C CE1 1 
ATOM 6291 C CE2 . TYR E 5 134 ? 350.906 365.092 432.525 1.00 115.05 ? 134 TYR C CE2 1 
ATOM 6292 C CZ  . TYR E 5 134 ? 351.773 364.408 433.341 1.00 115.05 ? 134 TYR C CZ  1 
ATOM 6293 O OH  . TYR E 5 134 ? 352.906 363.843 432.810 1.00 115.05 ? 134 TYR C OH  1 
ATOM 6294 N N   . SER E 5 135 ? 350.744 368.118 436.379 1.00 119.51 ? 135 SER C N   1 
ATOM 6295 C CA  . SER E 5 135 ? 351.928 368.864 435.974 1.00 119.51 ? 135 SER C CA  1 
ATOM 6296 C C   . SER E 5 135 ? 352.933 367.926 435.324 1.00 119.51 ? 135 SER C C   1 
ATOM 6297 O O   . SER E 5 135 ? 353.135 366.813 435.817 1.00 119.51 ? 135 SER C O   1 
ATOM 6298 C CB  . SER E 5 135 ? 352.560 369.551 437.166 1.00 119.51 ? 135 SER C CB  1 
ATOM 6299 O OG  . SER E 5 135 ? 351.591 370.314 437.855 1.00 119.51 ? 135 SER C OG  1 
ATOM 6300 N N   . PRO E 5 136 ? 353.576 368.331 434.235 1.00 122.07 ? 136 PRO C N   1 
ATOM 6301 C CA  . PRO E 5 136 ? 354.506 367.443 433.538 1.00 122.07 ? 136 PRO C CA  1 
ATOM 6302 C C   . PRO E 5 136 ? 355.803 367.302 434.313 1.00 122.07 ? 136 PRO C C   1 
ATOM 6303 O O   . PRO E 5 136 ? 356.051 368.074 435.251 1.00 122.07 ? 136 PRO C O   1 
ATOM 6304 C CB  . PRO E 5 136 ? 354.730 368.159 432.194 1.00 122.07 ? 136 PRO C CB  1 
ATOM 6305 C CG  . PRO E 5 136 ? 353.678 369.209 432.119 1.00 122.07 ? 136 PRO C CG  1 
ATOM 6306 C CD  . PRO E 5 136 ? 353.402 369.600 433.521 1.00 122.07 ? 136 PRO C CD  1 
ATOM 6307 N N   . PRO E 5 137 ? 356.642 366.317 433.980 1.00 122.12 ? 137 PRO C N   1 
ATOM 6308 C CA  . PRO E 5 137 ? 357.961 366.234 434.619 1.00 122.12 ? 137 PRO C CA  1 
ATOM 6309 C C   . PRO E 5 137 ? 358.842 367.402 434.208 1.00 122.12 ? 137 PRO C C   1 
ATOM 6310 O O   . PRO E 5 137 ? 359.143 367.589 433.029 1.00 122.12 ? 137 PRO C O   1 
ATOM 6311 C CB  . PRO E 5 137 ? 358.521 364.901 434.110 1.00 122.12 ? 137 PRO C CB  1 
ATOM 6312 C CG  . PRO E 5 137 ? 357.731 364.593 432.895 1.00 122.12 ? 137 PRO C CG  1 
ATOM 6313 C CD  . PRO E 5 137 ? 356.366 365.112 433.182 1.00 122.12 ? 137 PRO C CD  1 
ATOM 6314 N N   . GLY E 5 138 ? 359.250 368.190 435.194 1.00 124.52 ? 138 GLY C N   1 
ATOM 6315 C CA  . GLY E 5 138 ? 360.037 369.374 434.929 1.00 124.52 ? 138 GLY C CA  1 
ATOM 6316 C C   . GLY E 5 138 ? 359.346 370.639 435.385 1.00 124.52 ? 138 GLY C C   1 
ATOM 6317 O O   . GLY E 5 138 ? 359.987 371.539 435.934 1.00 124.52 ? 138 GLY C O   1 
ATOM 6318 N N   . ALA E 5 139 ? 358.038 370.724 435.169 1.00 126.59 ? 139 ALA C N   1 
ATOM 6319 C CA  . ALA E 5 139 ? 357.270 371.855 435.662 1.00 126.59 ? 139 ALA C CA  1 
ATOM 6320 C C   . ALA E 5 139 ? 356.971 371.670 437.140 1.00 126.59 ? 139 ALA C C   1 
ATOM 6321 O O   . ALA E 5 139 ? 356.843 370.544 437.626 1.00 126.59 ? 139 ALA C O   1 
ATOM 6322 C CB  . ALA E 5 139 ? 355.968 372.008 434.879 1.00 126.59 ? 139 ALA C CB  1 
ATOM 6323 N N   . GLY E 5 140 ? 356.864 372.779 437.855 1.00 123.77 ? 140 GLY C N   1 
ATOM 6324 C CA  . GLY E 5 140 ? 356.640 372.714 439.281 1.00 123.77 ? 140 GLY C CA  1 
ATOM 6325 C C   . GLY E 5 140 ? 355.206 372.389 439.639 1.00 123.77 ? 140 GLY C C   1 
ATOM 6326 O O   . GLY E 5 140 ? 354.319 372.313 438.792 1.00 123.77 ? 140 GLY C O   1 
ATOM 6327 N N   . VAL E 5 141 ? 354.988 372.182 440.929 1.00 119.17 ? 141 VAL C N   1 
ATOM 6328 C CA  . VAL E 5 141 ? 353.624 372.001 441.435 1.00 119.17 ? 141 VAL C CA  1 
ATOM 6329 C C   . VAL E 5 141 ? 352.920 373.354 441.469 1.00 119.17 ? 141 VAL C C   1 
ATOM 6330 O O   . VAL E 5 141 ? 353.547 374.366 441.832 1.00 119.17 ? 141 VAL C O   1 
ATOM 6331 C CB  . VAL E 5 141 ? 353.659 371.326 442.816 1.00 119.17 ? 141 VAL C CB  1 
ATOM 6332 C CG1 . VAL E 5 141 ? 354.561 372.069 443.801 1.00 119.17 ? 141 VAL C CG1 1 
ATOM 6333 C CG2 . VAL E 5 141 ? 352.264 371.166 443.400 1.00 119.17 ? 141 VAL C CG2 1 
ATOM 6334 N N   . PRO E 5 142 ? 351.670 373.455 441.017 1.00 117.61 ? 142 PRO C N   1 
ATOM 6335 C CA  . PRO E 5 142 ? 350.972 374.745 441.076 1.00 117.61 ? 142 PRO C CA  1 
ATOM 6336 C C   . PRO E 5 142 ? 350.589 375.090 442.505 1.00 117.61 ? 142 PRO C C   1 
ATOM 6337 O O   . PRO E 5 142 ? 350.082 374.249 443.246 1.00 117.61 ? 142 PRO C O   1 
ATOM 6338 C CB  . PRO E 5 142 ? 349.736 374.522 440.200 1.00 117.61 ? 142 PRO C CB  1 
ATOM 6339 C CG  . PRO E 5 142 ? 349.548 373.061 440.175 1.00 117.61 ? 142 PRO C CG  1 
ATOM 6340 C CD  . PRO E 5 142 ? 350.913 372.464 440.238 1.00 117.61 ? 142 PRO C CD  1 
ATOM 6341 N N   . LYS E 5 143 ? 350.842 376.334 442.887 1.00 116.74 ? 143 LYS C N   1 
ATOM 6342 C CA  . LYS E 5 143 ? 350.592 376.794 444.243 1.00 116.74 ? 143 LYS C CA  1 
ATOM 6343 C C   . LYS E 5 143 ? 349.275 377.539 444.377 1.00 116.74 ? 143 LYS C C   1 
ATOM 6344 O O   . LYS E 5 143 ? 349.007 378.114 445.435 1.00 116.74 ? 143 LYS C O   1 
ATOM 6345 C CB  . LYS E 5 143 ? 351.738 377.689 444.706 1.00 116.74 ? 143 LYS C CB  1 
ATOM 6346 C CG  . LYS E 5 143 ? 352.025 378.838 443.762 1.00 116.74 ? 143 LYS C CG  1 
ATOM 6347 C CD  . LYS E 5 143 ? 353.202 379.664 444.246 1.00 116.74 ? 143 LYS C CD  1 
ATOM 6348 C CE  . LYS E 5 143 ? 354.504 378.906 444.074 1.00 116.74 ? 143 LYS C CE  1 
ATOM 6349 N NZ  . LYS E 5 143 ? 354.570 378.219 442.755 1.00 116.74 ? 143 LYS C NZ  1 
ATOM 6350 N N   . ASN E 5 144 ? 348.446 377.527 443.340 1.00 120.83 ? 144 ASN C N   1 
ATOM 6351 C CA  . ASN E 5 144 ? 347.250 378.349 443.295 1.00 120.83 ? 144 ASN C CA  1 
ATOM 6352 C C   . ASN E 5 144 ? 346.332 377.745 442.242 1.00 120.83 ? 144 ASN C C   1 
ATOM 6353 O O   . ASN E 5 144 ? 346.785 377.043 441.337 1.00 120.83 ? 144 ASN C O   1 
ATOM 6354 C CB  . ASN E 5 144 ? 347.622 379.808 442.991 1.00 120.83 ? 144 ASN C CB  1 
ATOM 6355 C CG  . ASN E 5 144 ? 346.431 380.730 442.941 1.00 120.83 ? 144 ASN C CG  1 
ATOM 6356 O OD1 . ASN E 5 144 ? 345.357 380.410 443.448 1.00 120.83 ? 144 ASN C OD1 1 
ATOM 6357 N ND2 . ASN E 5 144 ? 346.615 381.892 442.328 1.00 120.83 ? 144 ASN C ND2 1 
ATOM 6358 N N   . ARG E 5 145 ? 345.029 377.993 442.387 1.00 116.17 ? 145 ARG C N   1 
ATOM 6359 C CA  . ARG E 5 145 ? 344.064 377.413 441.459 1.00 116.17 ? 145 ARG C CA  1 
ATOM 6360 C C   . ARG E 5 145 ? 344.192 378.005 440.063 1.00 116.17 ? 145 ARG C C   1 
ATOM 6361 O O   . ARG E 5 145 ? 343.921 377.315 439.075 1.00 116.17 ? 145 ARG C O   1 
ATOM 6362 C CB  . ARG E 5 145 ? 342.644 377.609 441.984 1.00 116.17 ? 145 ARG C CB  1 
ATOM 6363 C CG  . ARG E 5 145 ? 341.601 376.757 441.286 1.00 116.17 ? 145 ARG C CG  1 
ATOM 6364 C CD  . ARG E 5 145 ? 340.233 377.390 441.357 1.00 116.17 ? 145 ARG C CD  1 
ATOM 6365 N NE  . ARG E 5 145 ? 340.225 378.736 440.800 1.00 116.17 ? 145 ARG C NE  1 
ATOM 6366 C CZ  . ARG E 5 145 ? 339.981 379.013 439.526 1.00 116.17 ? 145 ARG C CZ  1 
ATOM 6367 N NH1 . ARG E 5 145 ? 339.993 380.267 439.105 1.00 116.17 ? 145 ARG C NH1 1 
ATOM 6368 N NH2 . ARG E 5 145 ? 339.727 378.036 438.673 1.00 116.17 ? 145 ARG C NH2 1 
ATOM 6369 N N   . LYS E 5 146 ? 344.625 379.264 439.961 1.00 120.90 ? 146 LYS C N   1 
ATOM 6370 C CA  . LYS E 5 146 ? 344.636 379.937 438.668 1.00 120.90 ? 146 LYS C CA  1 
ATOM 6371 C C   . LYS E 5 146 ? 345.719 379.381 437.755 1.00 120.90 ? 146 LYS C C   1 
ATOM 6372 O O   . LYS E 5 146 ? 345.448 379.073 436.591 1.00 120.90 ? 146 LYS C O   1 
ATOM 6373 C CB  . LYS E 5 146 ? 344.815 381.438 438.853 1.00 120.90 ? 146 LYS C CB  1 
ATOM 6374 C CG  . LYS E 5 146 ? 344.637 382.213 437.571 1.00 120.90 ? 146 LYS C CG  1 
ATOM 6375 C CD  . LYS E 5 146 ? 345.249 383.593 437.667 1.00 120.90 ? 146 LYS C CD  1 
ATOM 6376 C CE  . LYS E 5 146 ? 345.233 384.287 436.320 1.00 120.90 ? 146 LYS C CE  1 
ATOM 6377 N NZ  . LYS E 5 146 ? 345.831 385.643 436.398 1.00 120.90 ? 146 LYS C NZ  1 
ATOM 6378 N N   . ASP E 5 147 ? 346.943 379.227 438.254 1.00 126.42 ? 147 ASP C N   1 
ATOM 6379 C CA  . ASP E 5 147 ? 347.981 378.618 437.433 1.00 126.42 ? 147 ASP C CA  1 
ATOM 6380 C C   . ASP E 5 147 ? 347.952 377.101 437.483 1.00 126.42 ? 147 ASP C C   1 
ATOM 6381 O O   . ASP E 5 147 ? 348.782 376.462 436.832 1.00 126.42 ? 147 ASP C O   1 
ATOM 6382 C CB  . ASP E 5 147 ? 349.369 379.116 437.836 1.00 126.42 ? 147 ASP C CB  1 
ATOM 6383 C CG  . ASP E 5 147 ? 349.552 379.171 439.319 1.00 126.42 ? 147 ASP C CG  1 
ATOM 6384 O OD1 . ASP E 5 147 ? 348.583 378.865 440.032 1.00 126.42 ? 147 ASP C OD1 1 
ATOM 6385 O OD2 . ASP E 5 147 ? 350.660 379.518 439.775 1.00 126.42 ? 147 ASP C OD2 1 
ATOM 6386 N N   . ALA E 5 148 ? 347.035 376.511 438.244 1.00 120.42 ? 148 ALA C N   1 
ATOM 6387 C CA  . ALA E 5 148 ? 346.681 375.122 438.010 1.00 120.42 ? 148 ALA C CA  1 
ATOM 6388 C C   . ALA E 5 148 ? 345.682 374.991 436.876 1.00 120.42 ? 148 ALA C C   1 
ATOM 6389 O O   . ALA E 5 148 ? 345.609 373.934 436.246 1.00 120.42 ? 148 ALA C O   1 
ATOM 6390 C CB  . ALA E 5 148 ? 346.109 374.489 439.275 1.00 120.42 ? 148 ALA C CB  1 
ATOM 6391 N N   . MET E 5 149 ? 344.916 376.048 436.610 1.00 121.48 ? 149 MET C N   1 
ATOM 6392 C CA  . MET E 5 149 ? 344.009 376.064 435.473 1.00 121.48 ? 149 MET C CA  1 
ATOM 6393 C C   . MET E 5 149 ? 344.753 376.281 434.163 1.00 121.48 ? 149 MET C C   1 
ATOM 6394 O O   . MET E 5 149 ? 344.313 375.795 433.116 1.00 121.48 ? 149 MET C O   1 
ATOM 6395 C CB  . MET E 5 149 ? 342.951 377.150 435.678 1.00 121.48 ? 149 MET C CB  1 
ATOM 6396 C CG  . MET E 5 149 ? 341.805 377.135 434.695 1.00 121.48 ? 149 MET C CG  1 
ATOM 6397 S SD  . MET E 5 149 ? 342.038 378.347 433.392 1.00 121.48 ? 149 MET C SD  1 
ATOM 6398 C CE  . MET E 5 149 ? 342.183 379.840 434.359 1.00 121.48 ? 149 MET C CE  1 
ATOM 6399 N N   . LEU E 5 150 ? 345.879 376.989 434.195 1.00 120.15 ? 150 LEU C N   1 
ATOM 6400 C CA  . LEU E 5 150 ? 346.617 377.258 432.970 1.00 120.15 ? 150 LEU C CA  1 
ATOM 6401 C C   . LEU E 5 150 ? 347.400 376.053 432.473 1.00 120.15 ? 150 LEU C C   1 
ATOM 6402 O O   . LEU E 5 150 ? 347.727 375.999 431.285 1.00 120.15 ? 150 LEU C O   1 
ATOM 6403 C CB  . LEU E 5 150 ? 347.557 378.443 433.175 1.00 120.15 ? 150 LEU C CB  1 
ATOM 6404 C CG  . LEU E 5 150 ? 346.863 379.715 433.659 1.00 120.15 ? 150 LEU C CG  1 
ATOM 6405 C CD1 . LEU E 5 150 ? 347.861 380.828 433.864 1.00 120.15 ? 150 LEU C CD1 1 
ATOM 6406 C CD2 . LEU E 5 150 ? 345.789 380.142 432.688 1.00 120.15 ? 150 LEU C CD2 1 
ATOM 6407 N N   . GLY E 5 151 ? 347.697 375.088 433.336 1.00 118.16 ? 151 GLY C N   1 
ATOM 6408 C CA  . GLY E 5 151 ? 348.265 373.828 432.905 1.00 118.16 ? 151 GLY C CA  1 
ATOM 6409 C C   . GLY E 5 151 ? 347.175 372.920 432.384 1.00 118.16 ? 151 GLY C C   1 
ATOM 6410 O O   . GLY E 5 151 ? 346.004 373.297 432.311 1.00 118.16 ? 151 GLY C O   1 
ATOM 6411 N N   . THR E 5 152 ? 347.558 371.704 432.016 1.00 113.90 ? 152 THR C N   1 
ATOM 6412 C CA  . THR E 5 152 ? 346.583 370.750 431.511 1.00 113.90 ? 152 THR C CA  1 
ATOM 6413 C C   . THR E 5 152 ? 345.736 370.215 432.657 1.00 113.90 ? 152 THR C C   1 
ATOM 6414 O O   . THR E 5 152 ? 346.242 369.917 433.741 1.00 113.90 ? 152 THR C O   1 
ATOM 6415 C CB  . THR E 5 152 ? 347.261 369.616 430.736 1.00 113.90 ? 152 THR C CB  1 
ATOM 6416 O OG1 . THR E 5 152 ? 346.283 368.648 430.339 1.00 113.90 ? 152 THR C OG1 1 
ATOM 6417 C CG2 . THR E 5 152 ? 348.369 368.955 431.522 1.00 113.90 ? 152 THR C CG2 1 
ATOM 6418 N N   . HIS E 5 153 ? 344.428 370.147 432.427 1.00 107.75 ? 153 HIS C N   1 
ATOM 6419 C CA  . HIS E 5 153 ? 343.497 369.847 433.501 1.00 107.75 ? 153 HIS C CA  1 
ATOM 6420 C C   . HIS E 5 153 ? 342.209 369.305 432.914 1.00 107.75 ? 153 HIS C C   1 
ATOM 6421 O O   . HIS E 5 153 ? 341.991 369.340 431.702 1.00 107.75 ? 153 HIS C O   1 
ATOM 6422 C CB  . HIS E 5 153 ? 343.202 371.086 434.343 1.00 107.75 ? 153 HIS C CB  1 
ATOM 6423 C CG  . HIS E 5 153 ? 342.494 372.166 433.592 1.00 107.75 ? 153 HIS C CG  1 
ATOM 6424 N ND1 . HIS E 5 153 ? 341.154 372.435 433.762 1.00 107.75 ? 153 HIS C ND1 1 
ATOM 6425 C CD2 . HIS E 5 153 ? 342.937 373.042 432.663 1.00 107.75 ? 153 HIS C CD2 1 
ATOM 6426 C CE1 . HIS E 5 153 ? 340.804 373.434 432.973 1.00 107.75 ? 153 HIS C CE1 1 
ATOM 6427 N NE2 . HIS E 5 153 ? 341.869 373.823 432.297 1.00 107.75 ? 153 HIS C NE2 1 
ATOM 6428 N N   . VAL E 5 154 ? 341.359 368.797 433.801 1.00 102.18 ? 154 VAL C N   1 
ATOM 6429 C CA  . VAL E 5 154 ? 340.025 368.317 433.465 1.00 102.18 ? 154 VAL C CA  1 
ATOM 6430 C C   . VAL E 5 154 ? 339.089 368.824 434.546 1.00 102.18 ? 154 VAL C C   1 
ATOM 6431 O O   . VAL E 5 154 ? 339.317 368.567 435.733 1.00 102.18 ? 154 VAL C O   1 
ATOM 6432 C CB  . VAL E 5 154 ? 339.964 366.782 433.373 1.00 102.18 ? 154 VAL C CB  1 
ATOM 6433 C CG1 . VAL E 5 154 ? 338.530 366.296 433.426 1.00 102.18 ? 154 VAL C CG1 1 
ATOM 6434 C CG2 . VAL E 5 154 ? 340.627 366.291 432.102 1.00 102.18 ? 154 VAL C CG2 1 
ATOM 6435 N N   . ILE E 5 155 ? 338.057 369.557 434.151 1.00 103.52 ? 155 ILE C N   1 
ATOM 6436 C CA  . ILE E 5 155 ? 337.056 370.046 435.089 1.00 103.52 ? 155 ILE C CA  1 
ATOM 6437 C C   . ILE E 5 155 ? 335.989 368.973 435.274 1.00 103.52 ? 155 ILE C C   1 
ATOM 6438 O O   . ILE E 5 155 ? 335.357 368.533 434.308 1.00 103.52 ? 155 ILE C O   1 
ATOM 6439 C CB  . ILE E 5 155 ? 336.454 371.376 434.611 1.00 103.52 ? 155 ILE C CB  1 
ATOM 6440 C CG1 . ILE E 5 155 ? 335.143 371.662 435.330 1.00 103.52 ? 155 ILE C CG1 1 
ATOM 6441 C CG2 . ILE E 5 155 ? 336.305 371.410 433.105 1.00 103.52 ? 155 ILE C CG2 1 
ATOM 6442 C CD1 . ILE E 5 155 ? 334.606 373.022 435.047 1.00 103.52 ? 155 ILE C CD1 1 
ATOM 6443 N N   . TRP E 5 156 ? 335.805 368.535 436.515 1.00 102.90 ? 156 TRP C N   1 
ATOM 6444 C CA  . TRP E 5 156 ? 334.991 367.367 436.833 1.00 102.90 ? 156 TRP C CA  1 
ATOM 6445 C C   . TRP E 5 156 ? 333.707 367.836 437.498 1.00 102.90 ? 156 TRP C C   1 
ATOM 6446 O O   . TRP E 5 156 ? 333.733 368.326 438.630 1.00 102.90 ? 156 TRP C O   1 
ATOM 6447 C CB  . TRP E 5 156 ? 335.763 366.409 437.737 1.00 102.90 ? 156 TRP C CB  1 
ATOM 6448 C CG  . TRP E 5 156 ? 335.031 365.158 438.075 1.00 102.90 ? 156 TRP C CG  1 
ATOM 6449 C CD1 . TRP E 5 156 ? 334.081 364.542 437.328 1.00 102.90 ? 156 TRP C CD1 1 
ATOM 6450 C CD2 . TRP E 5 156 ? 335.196 364.362 439.250 1.00 102.90 ? 156 TRP C CD2 1 
ATOM 6451 N NE1 . TRP E 5 156 ? 333.636 363.414 437.966 1.00 102.90 ? 156 TRP C NE1 1 
ATOM 6452 C CE2 . TRP E 5 156 ? 334.307 363.283 439.150 1.00 102.90 ? 156 TRP C CE2 1 
ATOM 6453 C CE3 . TRP E 5 156 ? 336.008 364.460 440.379 1.00 102.90 ? 156 TRP C CE3 1 
ATOM 6454 C CZ2 . TRP E 5 156 ? 334.207 362.313 440.129 1.00 102.90 ? 156 TRP C CZ2 1 
ATOM 6455 C CZ3 . TRP E 5 156 ? 335.906 363.498 441.348 1.00 102.90 ? 156 TRP C CZ3 1 
ATOM 6456 C CH2 . TRP E 5 156 ? 335.013 362.437 441.219 1.00 102.90 ? 156 TRP C CH2 1 
ATOM 6457 N N   . ASP E 5 157 ? 332.588 367.680 436.800 1.00 111.10 ? 157 ASP C N   1 
ATOM 6458 C CA  . ASP E 5 157 ? 331.289 368.052 437.339 1.00 111.10 ? 157 ASP C CA  1 
ATOM 6459 C C   . ASP E 5 157 ? 330.689 366.856 438.057 1.00 111.10 ? 157 ASP C C   1 
ATOM 6460 O O   . ASP E 5 157 ? 330.477 365.802 437.453 1.00 111.10 ? 157 ASP C O   1 
ATOM 6461 C CB  . ASP E 5 157 ? 330.353 368.532 436.232 1.00 111.10 ? 157 ASP C CB  1 
ATOM 6462 C CG  . ASP E 5 157 ? 329.281 369.475 436.745 1.00 111.10 ? 157 ASP C CG  1 
ATOM 6463 O OD1 . ASP E 5 157 ? 328.578 369.124 437.714 1.00 111.10 ? 157 ASP C OD1 1 
ATOM 6464 O OD2 . ASP E 5 157 ? 329.140 370.575 436.175 1.00 111.10 ? 157 ASP C OD2 1 
ATOM 6465 N N   . VAL E 5 158 ? 330.406 367.029 439.342 1.00 106.18 ? 158 VAL C N   1 
ATOM 6466 C CA  . VAL E 5 158 ? 329.994 365.910 440.177 1.00 106.18 ? 158 VAL C CA  1 
ATOM 6467 C C   . VAL E 5 158 ? 328.536 365.553 439.931 1.00 106.18 ? 158 VAL C C   1 
ATOM 6468 O O   . VAL E 5 158 ? 328.162 364.376 439.930 1.00 106.18 ? 158 VAL C O   1 
ATOM 6469 C CB  . VAL E 5 158 ? 330.255 366.249 441.649 1.00 106.18 ? 158 VAL C CB  1 
ATOM 6470 C CG1 . VAL E 5 158 ? 330.060 365.049 442.491 1.00 106.18 ? 158 VAL C CG1 1 
ATOM 6471 C CG2 . VAL E 5 158 ? 331.657 366.755 441.809 1.00 106.18 ? 158 VAL C CG2 1 
ATOM 6472 N N   . GLY E 5 159 ? 327.690 366.560 439.714 1.00 113.40 ? 159 GLY C N   1 
ATOM 6473 C CA  . GLY E 5 159 ? 326.273 366.310 439.515 1.00 113.40 ? 159 GLY C CA  1 
ATOM 6474 C C   . GLY E 5 159 ? 325.936 365.623 438.209 1.00 113.40 ? 159 GLY C C   1 
ATOM 6475 O O   . GLY E 5 159 ? 324.899 364.960 438.121 1.00 113.40 ? 159 GLY C O   1 
ATOM 6476 N N   . LEU E 5 160 ? 326.791 365.755 437.200 1.00 114.62 ? 160 LEU C N   1 
ATOM 6477 C CA  . LEU E 5 160 ? 326.549 365.103 435.921 1.00 114.62 ? 160 LEU C CA  1 
ATOM 6478 C C   . LEU E 5 160 ? 327.073 363.677 435.896 1.00 114.62 ? 160 LEU C C   1 
ATOM 6479 O O   . LEU E 5 160 ? 326.299 362.736 435.700 1.00 114.62 ? 160 LEU C O   1 
ATOM 6480 C CB  . LEU E 5 160 ? 327.197 365.902 434.792 1.00 114.62 ? 160 LEU C CB  1 
ATOM 6481 C CG  . LEU E 5 160 ? 326.616 367.272 434.448 1.00 114.62 ? 160 LEU C CG  1 
ATOM 6482 C CD1 . LEU E 5 160 ? 327.015 367.658 433.039 1.00 114.62 ? 160 LEU C CD1 1 
ATOM 6483 C CD2 . LEU E 5 160 ? 325.104 367.287 434.593 1.00 114.62 ? 160 LEU C CD2 1 
ATOM 6484 N N   . GLN E 5 161 ? 328.373 363.498 436.100 1.00 111.80 ? 161 GLN C N   1 
ATOM 6485 C CA  . GLN E 5 161 ? 328.990 362.183 436.045 1.00 111.80 ? 161 GLN C CA  1 
ATOM 6486 C C   . GLN E 5 161 ? 329.636 361.885 437.384 1.00 111.80 ? 161 GLN C C   1 
ATOM 6487 O O   . GLN E 5 161 ? 330.018 362.805 438.109 1.00 111.80 ? 161 GLN C O   1 
ATOM 6488 C CB  . GLN E 5 161 ? 330.021 362.108 434.920 1.00 111.80 ? 161 GLN C CB  1 
ATOM 6489 C CG  . GLN E 5 161 ? 331.095 363.162 435.002 1.00 111.80 ? 161 GLN C CG  1 
ATOM 6490 C CD  . GLN E 5 161 ? 332.015 363.125 433.810 1.00 111.80 ? 161 GLN C CD  1 
ATOM 6491 O OE1 . GLN E 5 161 ? 331.909 362.243 432.960 1.00 111.80 ? 161 GLN C OE1 1 
ATOM 6492 N NE2 . GLN E 5 161 ? 332.923 364.086 433.733 1.00 111.80 ? 161 GLN C NE2 1 
ATOM 6493 N N   . SER E 5 162 ? 329.742 360.606 437.713 1.00 108.71 ? 162 SER C N   1 
ATOM 6494 C CA  . SER E 5 162 ? 330.238 360.191 439.012 1.00 108.71 ? 162 SER C CA  1 
ATOM 6495 C C   . SER E 5 162 ? 331.638 359.601 438.965 1.00 108.71 ? 162 SER C C   1 
ATOM 6496 O O   . SER E 5 162 ? 332.120 359.122 439.994 1.00 108.71 ? 162 SER C O   1 
ATOM 6497 C CB  . SER E 5 162 ? 329.282 359.178 439.635 1.00 108.71 ? 162 SER C CB  1 
ATOM 6498 O OG  . SER E 5 162 ? 329.515 359.065 441.024 1.00 108.71 ? 162 SER C OG  1 
ATOM 6499 N N   . SER E 5 163 ? 332.304 359.623 437.813 1.00 109.19 ? 163 SER C N   1 
ATOM 6500 C CA  . SER E 5 163 ? 333.637 359.047 437.706 1.00 109.19 ? 163 SER C CA  1 
ATOM 6501 C C   . SER E 5 163 ? 334.387 359.730 436.577 1.00 109.19 ? 163 SER C C   1 
ATOM 6502 O O   . SER E 5 163 ? 333.842 359.896 435.484 1.00 109.19 ? 163 SER C O   1 
ATOM 6503 C CB  . SER E 5 163 ? 333.564 357.544 437.450 1.00 109.19 ? 163 SER C CB  1 
ATOM 6504 O OG  . SER E 5 163 ? 333.199 357.287 436.109 1.00 109.19 ? 163 SER C OG  1 
ATOM 6505 N N   . CYS E 5 164 ? 335.632 360.113 436.838 1.00 107.80 ? 164 CYS C N   1 
ATOM 6506 C CA  . CYS E 5 164 ? 336.470 360.761 435.842 1.00 107.80 ? 164 CYS C CA  1 
ATOM 6507 C C   . CYS E 5 164 ? 337.738 359.948 435.647 1.00 107.80 ? 164 CYS C C   1 
ATOM 6508 O O   . CYS E 5 164 ? 338.402 359.581 436.617 1.00 107.80 ? 164 CYS C O   1 
ATOM 6509 C CB  . CYS E 5 164 ? 336.828 362.182 436.253 1.00 107.80 ? 164 CYS C CB  1 
ATOM 6510 S SG  . CYS E 5 164 ? 338.063 362.938 435.197 1.00 107.80 ? 164 CYS C SG  1 
ATOM 6511 N N   . VAL E 5 165 ? 338.071 359.678 434.389 1.00 103.21 ? 165 VAL C N   1 
ATOM 6512 C CA  . VAL E 5 165 ? 339.198 358.830 434.021 1.00 103.21 ? 165 VAL C CA  1 
ATOM 6513 C C   . VAL E 5 165 ? 340.280 359.717 433.425 1.00 103.21 ? 165 VAL C C   1 
ATOM 6514 O O   . VAL E 5 165 ? 339.983 360.613 432.627 1.00 103.21 ? 165 VAL C O   1 
ATOM 6515 C CB  . VAL E 5 165 ? 338.765 357.736 433.032 1.00 103.21 ? 165 VAL C CB  1 
ATOM 6516 C CG1 . VAL E 5 165 ? 339.891 356.756 432.770 1.00 103.21 ? 165 VAL C CG1 1 
ATOM 6517 C CG2 . VAL E 5 165 ? 337.539 357.013 433.552 1.00 103.21 ? 165 VAL C CG2 1 
ATOM 6518 N N   . LEU E 5 166 ? 341.530 359.469 433.805 1.00 106.09 ? 166 LEU C N   1 
ATOM 6519 C CA  . LEU E 5 166 ? 342.657 360.314 433.423 1.00 106.09 ? 166 LEU C CA  1 
ATOM 6520 C C   . LEU E 5 166 ? 343.813 359.420 432.991 1.00 106.09 ? 166 LEU C C   1 
ATOM 6521 O O   . LEU E 5 166 ? 344.176 358.484 433.708 1.00 106.09 ? 166 LEU C O   1 
ATOM 6522 C CB  . LEU E 5 166 ? 343.055 361.222 434.587 1.00 106.09 ? 166 LEU C CB  1 
ATOM 6523 C CG  . LEU E 5 166 ? 344.069 362.340 434.381 1.00 106.09 ? 166 LEU C CG  1 
ATOM 6524 C CD1 . LEU E 5 166 ? 343.788 363.081 433.102 1.00 106.09 ? 166 LEU C CD1 1 
ATOM 6525 C CD2 . LEU E 5 166 ? 344.017 363.295 435.549 1.00 106.09 ? 166 LEU C CD2 1 
ATOM 6526 N N   . CYS E 5 167 ? 344.371 359.686 431.812 1.00 112.29 ? 167 CYS C N   1 
ATOM 6527 C CA  . CYS E 5 167 ? 345.512 358.928 431.316 1.00 112.29 ? 167 CYS C CA  1 
ATOM 6528 C C   . CYS E 5 167 ? 346.790 359.746 431.433 1.00 112.29 ? 167 CYS C C   1 
ATOM 6529 O O   . CYS E 5 167 ? 346.821 360.935 431.111 1.00 112.29 ? 167 CYS C O   1 
ATOM 6530 C CB  . CYS E 5 167 ? 345.296 358.517 429.863 1.00 112.29 ? 167 CYS C CB  1 
ATOM 6531 S SG  . CYS E 5 167 ? 346.282 357.109 429.331 1.00 112.29 ? 167 CYS C SG  1 
ATOM 6532 N N   . VAL E 5 168 ? 347.857 359.093 431.883 1.00 113.59 ? 168 VAL C N   1 
ATOM 6533 C CA  . VAL E 5 168 ? 349.105 359.784 432.203 1.00 113.59 ? 168 VAL C CA  1 
ATOM 6534 C C   . VAL E 5 168 ? 350.295 358.833 432.078 1.00 113.59 ? 168 VAL C C   1 
ATOM 6535 O O   . VAL E 5 168 ? 350.231 357.691 432.552 1.00 113.59 ? 168 VAL C O   1 
ATOM 6536 C CB  . VAL E 5 168 ? 349.011 360.434 433.596 1.00 113.59 ? 168 VAL C CB  1 
ATOM 6537 C CG1 . VAL E 5 168 ? 348.556 359.444 434.647 1.00 113.59 ? 168 VAL C CG1 1 
ATOM 6538 C CG2 . VAL E 5 168 ? 350.333 361.004 434.002 1.00 113.59 ? 168 VAL C CG2 1 
ATOM 6539 N N   . PRO E 5 169 ? 351.367 359.227 431.396 1.00 119.13 ? 169 PRO C N   1 
ATOM 6540 C CA  . PRO E 5 169 ? 352.576 358.396 431.359 1.00 119.13 ? 169 PRO C CA  1 
ATOM 6541 C C   . PRO E 5 169 ? 353.314 358.365 432.693 1.00 119.13 ? 169 PRO C C   1 
ATOM 6542 O O   . PRO E 5 169 ? 353.240 359.289 433.504 1.00 119.13 ? 169 PRO C O   1 
ATOM 6543 C CB  . PRO E 5 169 ? 353.433 359.059 430.272 1.00 119.13 ? 169 PRO C CB  1 
ATOM 6544 C CG  . PRO E 5 169 ? 352.831 360.402 430.053 1.00 119.13 ? 169 PRO C CG  1 
ATOM 6545 C CD  . PRO E 5 169 ? 351.384 360.272 430.362 1.00 119.13 ? 169 PRO C CD  1 
ATOM 6546 N N   . TRP E 5 170 ? 354.041 357.266 432.907 1.00 119.56 ? 170 TRP C N   1 
ATOM 6547 C CA  . TRP E 5 170 ? 354.776 357.048 434.150 1.00 119.56 ? 170 TRP C CA  1 
ATOM 6548 C C   . TRP E 5 170 ? 356.044 356.291 433.789 1.00 119.56 ? 170 TRP C C   1 
ATOM 6549 O O   . TRP E 5 170 ? 355.978 355.262 433.113 1.00 119.56 ? 170 TRP C O   1 
ATOM 6550 C CB  . TRP E 5 170 ? 353.912 356.269 435.153 1.00 119.56 ? 170 TRP C CB  1 
ATOM 6551 C CG  . TRP E 5 170 ? 354.317 356.338 436.621 1.00 119.56 ? 170 TRP C CG  1 
ATOM 6552 C CD1 . TRP E 5 170 ? 354.544 357.473 437.344 1.00 119.56 ? 170 TRP C CD1 1 
ATOM 6553 C CD2 . TRP E 5 170 ? 354.389 355.250 437.562 1.00 119.56 ? 170 TRP C CD2 1 
ATOM 6554 N NE1 . TRP E 5 170 ? 354.827 357.156 438.653 1.00 119.56 ? 170 TRP C NE1 1 
ATOM 6555 C CE2 . TRP E 5 170 ? 354.730 355.801 438.812 1.00 119.56 ? 170 TRP C CE2 1 
ATOM 6556 C CE3 . TRP E 5 170 ? 354.240 353.864 437.462 1.00 119.56 ? 170 TRP C CE3 1 
ATOM 6557 C CZ2 . TRP E 5 170 ? 354.916 355.019 439.951 1.00 119.56 ? 170 TRP C CZ2 1 
ATOM 6558 C CZ3 . TRP E 5 170 ? 354.419 353.094 438.596 1.00 119.56 ? 170 TRP C CZ3 1 
ATOM 6559 C CH2 . TRP E 5 170 ? 354.755 353.670 439.820 1.00 119.56 ? 170 TRP C CH2 1 
ATOM 6560 N N   . ILE E 5 171 ? 357.192 356.804 434.222 1.00 119.41 ? 171 ILE C N   1 
ATOM 6561 C CA  . ILE E 5 171 ? 358.498 356.330 433.780 1.00 119.41 ? 171 ILE C CA  1 
ATOM 6562 C C   . ILE E 5 171 ? 359.338 356.055 435.021 1.00 119.41 ? 171 ILE C C   1 
ATOM 6563 O O   . ILE E 5 171 ? 359.029 356.557 436.106 1.00 119.41 ? 171 ILE C O   1 
ATOM 6564 C CB  . ILE E 5 171 ? 359.161 357.378 432.851 1.00 119.41 ? 171 ILE C CB  1 
ATOM 6565 C CG1 . ILE E 5 171 ? 360.296 356.791 432.005 1.00 119.41 ? 171 ILE C CG1 1 
ATOM 6566 C CG2 . ILE E 5 171 ? 359.655 358.587 433.636 1.00 119.41 ? 171 ILE C CG2 1 
ATOM 6567 C CD1 . ILE E 5 171 ? 359.834 355.832 430.957 1.00 119.41 ? 171 ILE C CD1 1 
ATOM 6568 N N   . SER E 5 172 ? 360.377 355.236 434.877 1.00 114.40 ? 172 SER C N   1 
ATOM 6569 C CA  . SER E 5 172 ? 361.284 354.959 435.987 1.00 114.40 ? 172 SER C CA  1 
ATOM 6570 C C   . SER E 5 172 ? 362.296 356.079 436.180 1.00 114.40 ? 172 SER C C   1 
ATOM 6571 O O   . SER E 5 172 ? 363.264 355.926 436.922 1.00 114.40 ? 172 SER C O   1 
ATOM 6572 C CB  . SER E 5 172 ? 362.018 353.640 435.770 1.00 114.40 ? 172 SER C CB  1 
ATOM 6573 O OG  . SER E 5 172 ? 362.956 353.417 436.805 1.00 114.40 ? 172 SER C OG  1 
ATOM 6574 N N   . ALA E 5 186 ? 362.116 365.408 439.222 1.00 122.29 ? 186 ALA C N   1 
ATOM 6575 C CA  . ALA E 5 186 ? 360.667 365.347 439.353 1.00 122.29 ? 186 ALA C CA  1 
ATOM 6576 C C   . ALA E 5 186 ? 360.076 364.368 438.348 1.00 122.29 ? 186 ALA C C   1 
ATOM 6577 O O   . ALA E 5 186 ? 360.724 364.015 437.365 1.00 122.29 ? 186 ALA C O   1 
ATOM 6578 C CB  . ALA E 5 186 ? 360.063 366.725 439.172 1.00 122.29 ? 186 ALA C CB  1 
ATOM 6579 N N   . ALA E 5 187 ? 358.842 363.918 438.603 1.00 120.17 ? 187 ALA C N   1 
ATOM 6580 C CA  . ALA E 5 187 ? 358.189 362.989 437.690 1.00 120.17 ? 187 ALA C CA  1 
ATOM 6581 C C   . ALA E 5 187 ? 356.707 363.277 437.482 1.00 120.17 ? 187 ALA C C   1 
ATOM 6582 O O   . ALA E 5 187 ? 356.043 362.511 436.775 1.00 120.17 ? 187 ALA C O   1 
ATOM 6583 C CB  . ALA E 5 187 ? 358.364 361.550 438.176 1.00 120.17 ? 187 ALA C CB  1 
ATOM 6584 N N   . GLY E 5 188 ? 356.164 364.335 438.062 1.00 119.06 ? 188 GLY C N   1 
ATOM 6585 C CA  . GLY E 5 188 ? 354.779 364.712 437.836 1.00 119.06 ? 188 GLY C CA  1 
ATOM 6586 C C   . GLY E 5 188 ? 353.992 364.900 439.117 1.00 119.06 ? 188 GLY C C   1 
ATOM 6587 O O   . GLY E 5 188 ? 354.396 364.474 440.197 1.00 119.06 ? 188 GLY C O   1 
ATOM 6588 N N   . TYR E 5 189 ? 352.839 365.553 438.996 1.00 116.62 ? 189 TYR C N   1 
ATOM 6589 C CA  . TYR E 5 189 ? 351.950 365.792 440.121 1.00 116.62 ? 189 TYR C CA  1 
ATOM 6590 C C   . TYR E 5 189 ? 350.514 365.712 439.633 1.00 116.62 ? 189 TYR C C   1 
ATOM 6591 O O   . TYR E 5 189 ? 350.210 366.118 438.513 1.00 116.62 ? 189 TYR C O   1 
ATOM 6592 C CB  . TYR E 5 189 ? 352.202 367.155 440.758 1.00 116.62 ? 189 TYR C CB  1 
ATOM 6593 C CG  . TYR E 5 189 ? 353.350 367.172 441.724 1.00 116.62 ? 189 TYR C CG  1 
ATOM 6594 C CD1 . TYR E 5 189 ? 353.153 366.879 443.063 1.00 116.62 ? 189 TYR C CD1 1 
ATOM 6595 C CD2 . TYR E 5 189 ? 354.630 367.487 441.301 1.00 116.62 ? 189 TYR C CD2 1 
ATOM 6596 C CE1 . TYR E 5 189 ? 354.200 366.894 443.957 1.00 116.62 ? 189 TYR C CE1 1 
ATOM 6597 C CE2 . TYR E 5 189 ? 355.685 367.503 442.184 1.00 116.62 ? 189 TYR C CE2 1 
ATOM 6598 C CZ  . TYR E 5 189 ? 355.464 367.206 443.512 1.00 116.62 ? 189 TYR C CZ  1 
ATOM 6599 O OH  . TYR E 5 189 ? 356.514 367.223 444.399 1.00 116.62 ? 189 TYR C OH  1 
ATOM 6600 N N   . VAL E 5 190 ? 349.633 365.167 440.475 1.00 104.47 ? 190 VAL C N   1 
ATOM 6601 C CA  . VAL E 5 190 ? 348.237 364.941 440.107 1.00 104.47 ? 190 VAL C CA  1 
ATOM 6602 C C   . VAL E 5 190 ? 347.352 365.715 441.082 1.00 104.47 ? 190 VAL C C   1 
ATOM 6603 O O   . VAL E 5 190 ? 346.365 365.182 441.600 1.00 104.47 ? 190 VAL C O   1 
ATOM 6604 C CB  . VAL E 5 190 ? 347.873 363.442 440.069 1.00 104.47 ? 190 VAL C CB  1 
ATOM 6605 C CG1 . VAL E 5 190 ? 346.680 363.192 439.147 1.00 104.47 ? 190 VAL C CG1 1 
ATOM 6606 C CG2 . VAL E 5 190 ? 349.038 362.604 439.608 1.00 104.47 ? 190 VAL C CG2 1 
ATOM 6607 N N   . THR E 5 191 ? 347.773 366.932 441.426 1.00 106.78 ? 191 THR C N   1 
ATOM 6608 C CA  . THR E 5 191 ? 347.042 367.816 442.327 1.00 106.78 ? 191 THR C CA  1 
ATOM 6609 C C   . THR E 5 191 ? 345.611 368.073 441.852 1.00 106.78 ? 191 THR C C   1 
ATOM 6610 O O   . THR E 5 191 ? 345.325 368.163 440.656 1.00 106.78 ? 191 THR C O   1 
ATOM 6611 C CB  . THR E 5 191 ? 347.762 369.154 442.456 1.00 106.78 ? 191 THR C CB  1 
ATOM 6612 O OG1 . THR E 5 191 ? 347.651 369.866 441.221 1.00 106.78 ? 191 THR C OG1 1 
ATOM 6613 C CG2 . THR E 5 191 ? 349.223 368.936 442.748 1.00 106.78 ? 191 THR C CG2 1 
ATOM 6614 N N   . CYS E 5 192 ? 344.710 368.203 442.824 1.00 110.74 ? 192 CYS C N   1 
ATOM 6615 C CA  . CYS E 5 192 ? 343.279 368.354 442.599 1.00 110.74 ? 192 CYS C CA  1 
ATOM 6616 C C   . CYS E 5 192 ? 342.750 369.489 443.457 1.00 110.74 ? 192 CYS C C   1 
ATOM 6617 O O   . CYS E 5 192 ? 343.055 369.565 444.648 1.00 110.74 ? 192 CYS C O   1 
ATOM 6618 C CB  . CYS E 5 192 ? 342.536 367.063 442.935 1.00 110.74 ? 192 CYS C CB  1 
ATOM 6619 S SG  . CYS E 5 192 ? 340.742 367.177 442.942 1.00 110.74 ? 192 CYS C SG  1 
ATOM 6620 N N   . TRP E 5 193 ? 341.937 370.353 442.857 1.00 109.29 ? 193 TRP C N   1 
ATOM 6621 C CA  . TRP E 5 193 ? 341.560 371.612 443.476 1.00 109.29 ? 193 TRP C CA  1 
ATOM 6622 C C   . TRP E 5 193 ? 340.051 371.771 443.513 1.00 109.29 ? 193 TRP C C   1 
ATOM 6623 O O   . TRP E 5 193 ? 339.331 371.221 442.680 1.00 109.29 ? 193 TRP C O   1 
ATOM 6624 C CB  . TRP E 5 193 ? 342.162 372.797 442.725 1.00 109.29 ? 193 TRP C CB  1 
ATOM 6625 C CG  . TRP E 5 193 ? 343.640 372.785 442.683 1.00 109.29 ? 193 TRP C CG  1 
ATOM 6626 C CD1 . TRP E 5 193 ? 344.427 372.090 441.825 1.00 109.29 ? 193 TRP C CD1 1 
ATOM 6627 C CD2 . TRP E 5 193 ? 344.519 373.506 443.540 1.00 109.29 ? 193 TRP C CD2 1 
ATOM 6628 N NE1 . TRP E 5 193 ? 345.746 372.329 442.095 1.00 109.29 ? 193 TRP C NE1 1 
ATOM 6629 C CE2 . TRP E 5 193 ? 345.828 373.198 443.147 1.00 109.29 ? 193 TRP C CE2 1 
ATOM 6630 C CE3 . TRP E 5 193 ? 344.325 374.382 444.605 1.00 109.29 ? 193 TRP C CE3 1 
ATOM 6631 C CZ2 . TRP E 5 193 ? 346.936 373.733 443.778 1.00 109.29 ? 193 TRP C CZ2 1 
ATOM 6632 C CZ3 . TRP E 5 193 ? 345.426 374.912 445.230 1.00 109.29 ? 193 TRP C CZ3 1 
ATOM 6633 C CH2 . TRP E 5 193 ? 346.715 374.588 444.816 1.00 109.29 ? 193 TRP C CH2 1 
ATOM 6634 N N   . TYR E 5 194 ? 339.585 372.540 444.491 1.00 110.65 ? 194 TYR C N   1 
ATOM 6635 C CA  . TYR E 5 194 ? 338.186 372.937 444.538 1.00 110.65 ? 194 TYR C CA  1 
ATOM 6636 C C   . TYR E 5 194 ? 337.907 373.961 443.453 1.00 110.65 ? 194 TYR C C   1 
ATOM 6637 O O   . TYR E 5 194 ? 338.675 374.908 443.272 1.00 110.65 ? 194 TYR C O   1 
ATOM 6638 C CB  . TYR E 5 194 ? 337.845 373.545 445.895 1.00 110.65 ? 194 TYR C CB  1 
ATOM 6639 C CG  . TYR E 5 194 ? 337.419 372.565 446.952 1.00 110.65 ? 194 TYR C CG  1 
ATOM 6640 C CD1 . TYR E 5 194 ? 336.224 371.879 446.848 1.00 110.65 ? 194 TYR C CD1 1 
ATOM 6641 C CD2 . TYR E 5 194 ? 338.205 372.349 448.070 1.00 110.65 ? 194 TYR C CD2 1 
ATOM 6642 C CE1 . TYR E 5 194 ? 335.833 370.993 447.819 1.00 110.65 ? 194 TYR C CE1 1 
ATOM 6643 C CE2 . TYR E 5 194 ? 337.824 371.466 449.044 1.00 110.65 ? 194 TYR C CE2 1 
ATOM 6644 C CZ  . TYR E 5 194 ? 336.640 370.792 448.915 1.00 110.65 ? 194 TYR C CZ  1 
ATOM 6645 O OH  . TYR E 5 194 ? 336.262 369.908 449.895 1.00 110.65 ? 194 TYR C OH  1 
ATOM 6646 N N   . GLN E 5 195 ? 336.809 373.779 442.729 1.00 105.02 ? 195 GLN C N   1 
ATOM 6647 C CA  . GLN E 5 195 ? 336.334 374.844 441.856 1.00 105.02 ? 195 GLN C CA  1 
ATOM 6648 C C   . GLN E 5 195 ? 335.257 375.665 442.557 1.00 105.02 ? 195 GLN C C   1 
ATOM 6649 O O   . GLN E 5 195 ? 335.410 376.875 442.742 1.00 105.02 ? 195 GLN C O   1 
ATOM 6650 C CB  . GLN E 5 195 ? 335.816 374.261 440.541 1.00 105.02 ? 195 GLN C CB  1 
ATOM 6651 C CG  . GLN E 5 195 ? 335.128 375.271 439.661 1.00 105.02 ? 195 GLN C CG  1 
ATOM 6652 C CD  . GLN E 5 195 ? 336.096 376.059 438.826 1.00 105.02 ? 195 GLN C CD  1 
ATOM 6653 O OE1 . GLN E 5 195 ? 337.240 375.661 438.650 1.00 105.02 ? 195 GLN C OE1 1 
ATOM 6654 N NE2 . GLN E 5 195 ? 335.644 377.185 438.303 1.00 105.02 ? 195 GLN C NE2 1 
ATOM 6655 N N   . THR E 5 196 ? 334.167 375.018 442.953 1.00 110.88 ? 196 THR C N   1 
ATOM 6656 C CA  . THR E 5 196 ? 333.116 375.615 443.761 1.00 110.88 ? 196 THR C CA  1 
ATOM 6657 C C   . THR E 5 196 ? 332.875 374.746 444.985 1.00 110.88 ? 196 THR C C   1 
ATOM 6658 O O   . THR E 5 196 ? 333.388 373.633 445.093 1.00 110.88 ? 196 THR C O   1 
ATOM 6659 C CB  . THR E 5 196 ? 331.809 375.760 442.977 1.00 110.88 ? 196 THR C CB  1 
ATOM 6660 O OG1 . THR E 5 196 ? 331.312 374.460 442.648 1.00 110.88 ? 196 THR C OG1 1 
ATOM 6661 C CG2 . THR E 5 196 ? 332.009 376.562 441.708 1.00 110.88 ? 196 THR C CG2 1 
ATOM 6662 N N   . ASN E 5 197 ? 332.068 375.254 445.910 1.00 113.45 ? 197 ASN C N   1 
ATOM 6663 C CA  . ASN E 5 197 ? 331.743 374.501 447.109 1.00 113.45 ? 197 ASN C CA  1 
ATOM 6664 C C   . ASN E 5 197 ? 330.718 373.420 446.791 1.00 113.45 ? 197 ASN C C   1 
ATOM 6665 O O   . ASN E 5 197 ? 330.167 373.348 445.691 1.00 113.45 ? 197 ASN C O   1 
ATOM 6666 C CB  . ASN E 5 197 ? 331.228 375.435 448.195 1.00 113.45 ? 197 ASN C CB  1 
ATOM 6667 C CG  . ASN E 5 197 ? 332.179 376.562 448.475 1.00 113.45 ? 197 ASN C CG  1 
ATOM 6668 O OD1 . ASN E 5 197 ? 333.286 376.597 447.941 1.00 113.45 ? 197 ASN C OD1 1 
ATOM 6669 N ND2 . ASN E 5 197 ? 331.756 377.501 449.310 1.00 113.45 ? 197 ASN C ND2 1 
ATOM 6670 N N   . ILE E 5 198 ? 330.453 372.564 447.771 1.00 113.39 ? 198 ILE C N   1 
ATOM 6671 C CA  . ILE E 5 198 ? 329.483 371.486 447.624 1.00 113.39 ? 198 ILE C CA  1 
ATOM 6672 C C   . ILE E 5 198 ? 328.120 372.024 448.039 1.00 113.39 ? 198 ILE C C   1 
ATOM 6673 O O   . ILE E 5 198 ? 327.867 372.251 449.224 1.00 113.39 ? 198 ILE C O   1 
ATOM 6674 C CB  . ILE E 5 198 ? 329.873 370.261 448.459 1.00 113.39 ? 198 ILE C CB  1 
ATOM 6675 C CG1 . ILE E 5 198 ? 331.307 369.840 448.157 1.00 113.39 ? 198 ILE C CG1 1 
ATOM 6676 C CG2 . ILE E 5 198 ? 328.935 369.115 448.178 1.00 113.39 ? 198 ILE C CG2 1 
ATOM 6677 C CD1 . ILE E 5 198 ? 331.517 369.391 446.741 1.00 113.39 ? 198 ILE C CD1 1 
ATOM 6678 N N   . VAL E 5 199 ? 327.244 372.236 447.067 1.00 109.71 ? 199 VAL C N   1 
ATOM 6679 C CA  . VAL E 5 199 ? 325.881 372.672 447.335 1.00 109.71 ? 199 VAL C CA  1 
ATOM 6680 C C   . VAL E 5 199 ? 325.072 371.455 447.748 1.00 109.71 ? 199 VAL C C   1 
ATOM 6681 O O   . VAL E 5 199 ? 325.230 370.373 447.173 1.00 109.71 ? 199 VAL C O   1 
ATOM 6682 C CB  . VAL E 5 199 ? 325.270 373.355 446.102 1.00 109.71 ? 199 VAL C CB  1 
ATOM 6683 C CG1 . VAL E 5 199 ? 323.974 374.048 446.459 1.00 109.71 ? 199 VAL C CG1 1 
ATOM 6684 C CG2 . VAL E 5 199 ? 326.252 374.345 445.521 1.00 109.71 ? 199 VAL C CG2 1 
ATOM 6685 N N   . VAL E 5 200 ? 324.211 371.619 448.749 1.00 109.36 ? 200 VAL C N   1 
ATOM 6686 C CA  . VAL E 5 200 ? 323.488 370.481 449.311 1.00 109.36 ? 200 VAL C CA  1 
ATOM 6687 C C   . VAL E 5 200 ? 322.119 370.941 449.785 1.00 109.36 ? 200 VAL C C   1 
ATOM 6688 O O   . VAL E 5 200 ? 321.926 372.101 450.174 1.00 109.36 ? 200 VAL C O   1 
ATOM 6689 C CB  . VAL E 5 200 ? 324.289 369.826 450.473 1.00 109.36 ? 200 VAL C CB  1 
ATOM 6690 C CG1 . VAL E 5 200 ? 324.140 370.546 451.818 1.00 109.36 ? 200 VAL C CG1 1 
ATOM 6691 C CG2 . VAL E 5 200 ? 324.024 368.346 450.582 1.00 109.36 ? 200 VAL C CG2 1 
ATOM 6692 N N   . PRO E 5 201 ? 321.109 370.079 449.638 1.00 108.29 ? 201 PRO C N   1 
ATOM 6693 C CA  . PRO E 5 201 ? 319.774 370.429 450.142 1.00 108.29 ? 201 PRO C CA  1 
ATOM 6694 C C   . PRO E 5 201 ? 319.624 370.231 451.638 1.00 108.29 ? 201 PRO C C   1 
ATOM 6695 O O   . PRO E 5 201 ? 320.597 369.940 452.337 1.00 108.29 ? 201 PRO C O   1 
ATOM 6696 C CB  . PRO E 5 201 ? 318.848 369.483 449.372 1.00 108.29 ? 201 PRO C CB  1 
ATOM 6697 C CG  . PRO E 5 201 ? 319.611 369.090 448.189 1.00 108.29 ? 201 PRO C CG  1 
ATOM 6698 C CD  . PRO E 5 201 ? 321.028 369.020 448.624 1.00 108.29 ? 201 PRO C CD  1 
ATOM 6699 N N   . ALA E 5 202 ? 318.406 370.398 452.141 1.00 110.84 ? 202 ALA C N   1 
ATOM 6700 C CA  . ALA E 5 202 ? 318.135 370.183 453.552 1.00 110.84 ? 202 ALA C CA  1 
ATOM 6701 C C   . ALA E 5 202 ? 318.090 368.696 453.869 1.00 110.84 ? 202 ALA C C   1 
ATOM 6702 O O   . ALA E 5 202 ? 317.675 367.881 453.041 1.00 110.84 ? 202 ALA C O   1 
ATOM 6703 C CB  . ALA E 5 202 ? 316.815 370.833 453.954 1.00 110.84 ? 202 ALA C CB  1 
ATOM 6704 N N   . ASP E 5 203 ? 318.525 368.362 455.089 1.00 115.67 ? 203 ASP C N   1 
ATOM 6705 C CA  . ASP E 5 203 ? 318.587 366.995 455.623 1.00 115.67 ? 203 ASP C CA  1 
ATOM 6706 C C   . ASP E 5 203 ? 319.431 366.063 454.759 1.00 115.67 ? 203 ASP C C   1 
ATOM 6707 O O   . ASP E 5 203 ? 319.105 364.887 454.601 1.00 115.67 ? 203 ASP C O   1 
ATOM 6708 C CB  . ASP E 5 203 ? 317.191 366.399 455.837 1.00 115.67 ? 203 ASP C CB  1 
ATOM 6709 C CG  . ASP E 5 203 ? 316.457 367.035 456.997 1.00 115.67 ? 203 ASP C CG  1 
ATOM 6710 O OD1 . ASP E 5 203 ? 316.735 366.656 458.152 1.00 115.67 ? 203 ASP C OD1 1 
ATOM 6711 O OD2 . ASP E 5 203 ? 315.602 367.914 456.759 1.00 115.67 ? 203 ASP C OD2 1 
ATOM 6712 N N   . VAL E 5 204 ? 320.518 366.577 454.187 1.00 111.66 ? 204 VAL C N   1 
ATOM 6713 C CA  . VAL E 5 204 ? 321.539 365.769 453.528 1.00 111.66 ? 204 VAL C CA  1 
ATOM 6714 C C   . VAL E 5 204 ? 322.882 366.147 454.136 1.00 111.66 ? 204 VAL C C   1 
ATOM 6715 O O   . VAL E 5 204 ? 323.154 367.331 454.355 1.00 111.66 ? 204 VAL C O   1 
ATOM 6716 C CB  . VAL E 5 204 ? 321.567 365.981 451.998 1.00 111.66 ? 204 VAL C CB  1 
ATOM 6717 C CG1 . VAL E 5 204 ? 322.473 364.971 451.333 1.00 111.66 ? 204 VAL C CG1 1 
ATOM 6718 C CG2 . VAL E 5 204 ? 320.187 365.903 451.393 1.00 111.66 ? 204 VAL C CG2 1 
ATOM 6719 N N   . GLN E 5 205 ? 323.714 365.148 454.422 1.00 117.04 ? 205 GLN C N   1 
ATOM 6720 C CA  . GLN E 5 205 ? 325.038 365.419 454.961 1.00 117.04 ? 205 GLN C CA  1 
ATOM 6721 C C   . GLN E 5 205 ? 325.940 366.021 453.887 1.00 117.04 ? 205 GLN C C   1 
ATOM 6722 O O   . GLN E 5 205 ? 325.780 365.775 452.690 1.00 117.04 ? 205 GLN C O   1 
ATOM 6723 C CB  . GLN E 5 205 ? 325.664 364.147 455.518 1.00 117.04 ? 205 GLN C CB  1 
ATOM 6724 C CG  . GLN E 5 205 ? 325.259 363.847 456.941 1.00 117.04 ? 205 GLN C CG  1 
ATOM 6725 C CD  . GLN E 5 205 ? 325.850 364.822 457.928 1.00 117.04 ? 205 GLN C CD  1 
ATOM 6726 O OE1 . GLN E 5 205 ? 327.029 365.156 457.854 1.00 117.04 ? 205 GLN C OE1 1 
ATOM 6727 N NE2 . GLN E 5 205 ? 325.032 365.288 458.861 1.00 117.04 ? 205 GLN C NE2 1 
ATOM 6728 N N   . SER E 5 206 ? 326.910 366.816 454.332 1.00 119.29 ? 206 SER C N   1 
ATOM 6729 C CA  . SER E 5 206 ? 327.773 367.563 453.428 1.00 119.29 ? 206 SER C CA  1 
ATOM 6730 C C   . SER E 5 206 ? 329.157 366.965 453.256 1.00 119.29 ? 206 SER C C   1 
ATOM 6731 O O   . SER E 5 206 ? 329.795 367.210 452.233 1.00 119.29 ? 206 SER C O   1 
ATOM 6732 C CB  . SER E 5 206 ? 327.924 369.007 453.914 1.00 119.29 ? 206 SER C CB  1 
ATOM 6733 O OG  . SER E 5 206 ? 326.677 369.671 453.907 1.00 119.29 ? 206 SER C OG  1 
ATOM 6734 N N   . SER E 5 207 ? 329.639 366.192 454.224 1.00 120.71 ? 207 SER C N   1 
ATOM 6735 C CA  . SER E 5 207 ? 330.989 365.636 454.179 1.00 120.71 ? 207 SER C CA  1 
ATOM 6736 C C   . SER E 5 207 ? 330.973 364.361 453.347 1.00 120.71 ? 207 SER C C   1 
ATOM 6737 O O   . SER E 5 207 ? 330.612 363.285 453.820 1.00 120.71 ? 207 SER C O   1 
ATOM 6738 C CB  . SER E 5 207 ? 331.501 365.373 455.588 1.00 120.71 ? 207 SER C CB  1 
ATOM 6739 O OG  . SER E 5 207 ? 331.578 366.580 456.323 1.00 120.71 ? 207 SER C OG  1 
ATOM 6740 N N   . CYS E 5 208 ? 331.375 364.483 452.089 1.00 117.66 ? 208 CYS C N   1 
ATOM 6741 C CA  . CYS E 5 208 ? 331.460 363.353 451.180 1.00 117.66 ? 208 CYS C CA  1 
ATOM 6742 C C   . CYS E 5 208 ? 332.913 362.926 451.014 1.00 117.66 ? 208 CYS C C   1 
ATOM 6743 O O   . CYS E 5 208 ? 333.836 363.580 451.499 1.00 117.66 ? 208 CYS C O   1 
ATOM 6744 C CB  . CYS E 5 208 ? 330.847 363.716 449.831 1.00 117.66 ? 208 CYS C CB  1 
ATOM 6745 S SG  . CYS E 5 208 ? 329.098 364.131 449.919 1.00 117.66 ? 208 CYS C SG  1 
ATOM 6746 N N   . ASP E 5 209 ? 333.116 361.815 450.310 1.00 111.88 ? 209 ASP C N   1 
ATOM 6747 C CA  . ASP E 5 209 ? 334.442 361.240 450.146 1.00 111.88 ? 209 ASP C CA  1 
ATOM 6748 C C   . ASP E 5 209 ? 334.661 360.827 448.697 1.00 111.88 ? 209 ASP C C   1 
ATOM 6749 O O   . ASP E 5 209 ? 333.725 360.747 447.900 1.00 111.88 ? 209 ASP C O   1 
ATOM 6750 C CB  . ASP E 5 209 ? 334.637 360.048 451.083 1.00 111.88 ? 209 ASP C CB  1 
ATOM 6751 C CG  . ASP E 5 209 ? 334.629 360.453 452.539 1.00 111.88 ? 209 ASP C CG  1 
ATOM 6752 O OD1 . ASP E 5 209 ? 335.263 361.471 452.876 1.00 111.88 ? 209 ASP C OD1 1 
ATOM 6753 O OD2 . ASP E 5 209 ? 333.974 359.767 453.346 1.00 111.88 ? 209 ASP C OD2 1 
ATOM 6754 N N   . ILE E 5 210 ? 335.923 360.567 448.357 1.00 104.12 ? 210 ILE C N   1 
ATOM 6755 C CA  . ILE E 5 210 ? 336.341 360.262 446.992 1.00 104.12 ? 210 ILE C CA  1 
ATOM 6756 C C   . ILE E 5 210 ? 337.331 359.107 447.044 1.00 104.12 ? 210 ILE C C   1 
ATOM 6757 O O   . ILE E 5 210 ? 338.265 359.129 447.849 1.00 104.12 ? 210 ILE C O   1 
ATOM 6758 C CB  . ILE E 5 210 ? 336.976 361.495 446.312 1.00 104.12 ? 210 ILE C CB  1 
ATOM 6759 C CG1 . ILE E 5 210 ? 335.913 362.527 445.949 1.00 104.12 ? 210 ILE C CG1 1 
ATOM 6760 C CG2 . ILE E 5 210 ? 337.748 361.118 445.062 1.00 104.12 ? 210 ILE C CG2 1 
ATOM 6761 C CD1 . ILE E 5 210 ? 336.473 363.767 445.308 1.00 104.12 ? 210 ILE C CD1 1 
ATOM 6762 N N   . LEU E 5 211 ? 337.128 358.094 446.205 1.00 100.52 ? 211 LEU C N   1 
ATOM 6763 C CA  . LEU E 5 211 ? 338.090 357.014 446.042 1.00 100.52 ? 211 LEU C CA  1 
ATOM 6764 C C   . LEU E 5 211 ? 338.988 357.274 444.838 1.00 100.52 ? 211 LEU C C   1 
ATOM 6765 O O   . LEU E 5 211 ? 338.669 358.076 443.960 1.00 100.52 ? 211 LEU C O   1 
ATOM 6766 C CB  . LEU E 5 211 ? 337.379 355.671 445.881 1.00 100.52 ? 211 LEU C CB  1 
ATOM 6767 C CG  . LEU E 5 211 ? 336.479 355.258 447.036 1.00 100.52 ? 211 LEU C CG  1 
ATOM 6768 C CD1 . LEU E 5 211 ? 335.873 353.913 446.756 1.00 100.52 ? 211 LEU C CD1 1 
ATOM 6769 C CD2 . LEU E 5 211 ? 337.275 355.215 448.309 1.00 100.52 ? 211 LEU C CD2 1 
ATOM 6770 N N   . CYS E 5 212 ? 340.119 356.571 444.801 1.00 97.93  ? 212 CYS C N   1 
ATOM 6771 C CA  . CYS E 5 212 ? 341.120 356.734 443.753 1.00 97.93  ? 212 CYS C CA  1 
ATOM 6772 C C   . CYS E 5 212 ? 341.601 355.375 443.277 1.00 97.93  ? 212 CYS C C   1 
ATOM 6773 O O   . CYS E 5 212 ? 342.009 354.544 444.090 1.00 97.93  ? 212 CYS C O   1 
ATOM 6774 C CB  . CYS E 5 212 ? 342.310 357.552 444.253 1.00 97.93  ? 212 CYS C CB  1 
ATOM 6775 S SG  . CYS E 5 212 ? 343.385 358.155 442.948 1.00 97.93  ? 212 CYS C SG  1 
ATOM 6776 N N   . PHE E 5 213 ? 341.584 355.162 441.966 1.00 97.20  ? 213 PHE C N   1 
ATOM 6777 C CA  . PHE E 5 213 ? 341.935 353.882 441.373 1.00 97.20  ? 213 PHE C CA  1 
ATOM 6778 C C   . PHE E 5 213 ? 343.113 354.053 440.426 1.00 97.20  ? 213 PHE C C   1 
ATOM 6779 O O   . PHE E 5 213 ? 343.289 355.112 439.822 1.00 97.20  ? 213 PHE C O   1 
ATOM 6780 C CB  . PHE E 5 213 ? 340.761 353.277 440.603 1.00 97.20  ? 213 PHE C CB  1 
ATOM 6781 C CG  . PHE E 5 213 ? 339.619 352.828 441.468 1.00 97.20  ? 213 PHE C CG  1 
ATOM 6782 C CD1 . PHE E 5 213 ? 338.715 353.738 441.984 1.00 97.20  ? 213 PHE C CD1 1 
ATOM 6783 C CD2 . PHE E 5 213 ? 339.429 351.490 441.732 1.00 97.20  ? 213 PHE C CD2 1 
ATOM 6784 C CE1 . PHE E 5 213 ? 337.666 353.323 442.764 1.00 97.20  ? 213 PHE C CE1 1 
ATOM 6785 C CE2 . PHE E 5 213 ? 338.379 351.074 442.510 1.00 97.20  ? 213 PHE C CE2 1 
ATOM 6786 C CZ  . PHE E 5 213 ? 337.498 351.993 443.024 1.00 97.20  ? 213 PHE C CZ  1 
ATOM 6787 N N   . VAL E 5 214 ? 343.913 352.999 440.285 1.00 102.73 ? 214 VAL C N   1 
ATOM 6788 C CA  . VAL E 5 214 ? 345.071 353.019 439.401 1.00 102.73 ? 214 VAL C CA  1 
ATOM 6789 C C   . VAL E 5 214 ? 345.157 351.677 438.683 1.00 102.73 ? 214 VAL C C   1 
ATOM 6790 O O   . VAL E 5 214 ? 344.714 350.646 439.195 1.00 102.73 ? 214 VAL C O   1 
ATOM 6791 C CB  . VAL E 5 214 ? 346.372 353.355 440.179 1.00 102.73 ? 214 VAL C CB  1 
ATOM 6792 C CG1 . VAL E 5 214 ? 346.864 352.185 441.009 1.00 102.73 ? 214 VAL C CG1 1 
ATOM 6793 C CG2 . VAL E 5 214 ? 347.464 353.867 439.251 1.00 102.73 ? 214 VAL C CG2 1 
ATOM 6794 N N   . SER E 5 215 ? 345.688 351.704 437.466 1.00 110.37 ? 215 SER C N   1 
ATOM 6795 C CA  . SER E 5 215 ? 345.740 350.537 436.596 1.00 110.37 ? 215 SER C CA  1 
ATOM 6796 C C   . SER E 5 215 ? 346.859 350.756 435.584 1.00 110.37 ? 215 SER C C   1 
ATOM 6797 O O   . SER E 5 215 ? 347.711 351.630 435.763 1.00 110.37 ? 215 SER C O   1 
ATOM 6798 C CB  . SER E 5 215 ? 344.387 350.313 435.920 1.00 110.37 ? 215 SER C CB  1 
ATOM 6799 O OG  . SER E 5 215 ? 344.326 349.047 435.298 1.00 110.37 ? 215 SER C OG  1 
ATOM 6800 N N   . ALA E 5 216 ? 346.867 349.956 434.521 1.00 113.55 ? 216 ALA C N   1 
ATOM 6801 C CA  . ALA E 5 216 ? 347.825 350.100 433.429 1.00 113.55 ? 216 ALA C CA  1 
ATOM 6802 C C   . ALA E 5 216 ? 347.038 350.251 432.136 1.00 113.55 ? 216 ALA C C   1 
ATOM 6803 O O   . ALA E 5 216 ? 346.246 349.372 431.785 1.00 113.55 ? 216 ALA C O   1 
ATOM 6804 C CB  . ALA E 5 216 ? 348.762 348.901 433.370 1.00 113.55 ? 216 ALA C CB  1 
ATOM 6805 N N   . CYS E 5 217 ? 347.229 351.370 431.438 1.00 119.27 ? 217 CYS C N   1 
ATOM 6806 C CA  . CYS E 5 217 ? 346.365 351.660 430.299 1.00 119.27 ? 217 CYS C CA  1 
ATOM 6807 C C   . CYS E 5 217 ? 346.794 350.875 429.068 1.00 119.27 ? 217 CYS C C   1 
ATOM 6808 O O   . CYS E 5 217 ? 346.066 349.994 428.598 1.00 119.27 ? 217 CYS C O   1 
ATOM 6809 C CB  . CYS E 5 217 ? 346.368 353.162 430.012 1.00 119.27 ? 217 CYS C CB  1 
ATOM 6810 S SG  . CYS E 5 217 ? 345.170 353.707 428.779 1.00 119.27 ? 217 CYS C SG  1 
ATOM 6811 N N   . ASN E 5 218 ? 347.972 351.170 428.537 1.00 129.22 ? 218 ASN C N   1 
ATOM 6812 C CA  . ASN E 5 218 ? 348.536 350.400 427.441 1.00 129.22 ? 218 ASN C CA  1 
ATOM 6813 C C   . ASN E 5 218 ? 349.512 349.383 428.009 1.00 129.22 ? 218 ASN C C   1 
ATOM 6814 O O   . ASN E 5 218 ? 349.560 349.135 429.215 1.00 129.22 ? 218 ASN C O   1 
ATOM 6815 C CB  . ASN E 5 218 ? 349.187 351.309 426.386 1.00 129.22 ? 218 ASN C CB  1 
ATOM 6816 C CG  . ASN E 5 218 ? 350.463 351.983 426.867 1.00 129.22 ? 218 ASN C CG  1 
ATOM 6817 O OD1 . ASN E 5 218 ? 351.536 351.384 426.881 1.00 129.22 ? 218 ASN C OD1 1 
ATOM 6818 N ND2 . ASN E 5 218 ? 350.351 353.250 427.237 1.00 129.22 ? 218 ASN C ND2 1 
ATOM 6819 N N   . ASP E 5 219 ? 350.290 348.791 427.117 1.00 132.19 ? 219 ASP C N   1 
ATOM 6820 C CA  . ASP E 5 219 ? 351.265 347.783 427.497 1.00 132.19 ? 219 ASP C CA  1 
ATOM 6821 C C   . ASP E 5 219 ? 352.491 348.425 428.140 1.00 132.19 ? 219 ASP C C   1 
ATOM 6822 O O   . ASP E 5 219 ? 353.223 349.180 427.494 1.00 132.19 ? 219 ASP C O   1 
ATOM 6823 C CB  . ASP E 5 219 ? 351.651 346.964 426.270 1.00 132.19 ? 219 ASP C CB  1 
ATOM 6824 C CG  . ASP E 5 219 ? 351.859 347.826 425.044 1.00 132.19 ? 219 ASP C CG  1 
ATOM 6825 O OD1 . ASP E 5 219 ? 351.602 349.047 425.125 1.00 132.19 ? 219 ASP C OD1 1 
ATOM 6826 O OD2 . ASP E 5 219 ? 352.258 347.279 423.995 1.00 132.19 ? 219 ASP C OD2 1 
ATOM 6827 N N   . PHE E 5 220 ? 352.720 348.114 429.412 1.00 122.64 ? 220 PHE C N   1 
ATOM 6828 C CA  . PHE E 5 220 ? 354.027 348.336 430.001 1.00 122.64 ? 220 PHE C CA  1 
ATOM 6829 C C   . PHE E 5 220 ? 355.069 347.439 429.344 1.00 122.64 ? 220 PHE C C   1 
ATOM 6830 O O   . PHE E 5 220 ? 354.761 346.423 428.717 1.00 122.64 ? 220 PHE C O   1 
ATOM 6831 C CB  . PHE E 5 220 ? 354.005 348.069 431.500 1.00 122.64 ? 220 PHE C CB  1 
ATOM 6832 C CG  . PHE E 5 220 ? 353.617 349.248 432.319 1.00 122.64 ? 220 PHE C CG  1 
ATOM 6833 C CD1 . PHE E 5 220 ? 354.579 350.158 432.709 1.00 122.64 ? 220 PHE C CD1 1 
ATOM 6834 C CD2 . PHE E 5 220 ? 352.313 349.450 432.695 1.00 122.64 ? 220 PHE C CD2 1 
ATOM 6835 C CE1 . PHE E 5 220 ? 354.245 351.248 433.471 1.00 122.64 ? 220 PHE C CE1 1 
ATOM 6836 C CE2 . PHE E 5 220 ? 351.972 350.543 433.455 1.00 122.64 ? 220 PHE C CE2 1 
ATOM 6837 C CZ  . PHE E 5 220 ? 352.943 351.445 433.842 1.00 122.64 ? 220 PHE C CZ  1 
ATOM 6838 N N   . SER E 5 221 ? 356.329 347.819 429.516 1.00 125.44 ? 221 SER C N   1 
ATOM 6839 C CA  . SER E 5 221 ? 357.456 347.051 429.005 1.00 125.44 ? 221 SER C CA  1 
ATOM 6840 C C   . SER E 5 221 ? 358.461 346.899 430.132 1.00 125.44 ? 221 SER C C   1 
ATOM 6841 O O   . SER E 5 221 ? 359.252 347.812 430.383 1.00 125.44 ? 221 SER C O   1 
ATOM 6842 C CB  . SER E 5 221 ? 358.092 347.740 427.801 1.00 125.44 ? 221 SER C CB  1 
ATOM 6843 O OG  . SER E 5 221 ? 359.067 348.673 428.223 1.00 125.44 ? 221 SER C OG  1 
ATOM 6844 N N   . VAL E 5 222 ? 358.437 345.754 430.800 1.00 121.91 ? 222 VAL C N   1 
ATOM 6845 C CA  . VAL E 5 222 ? 359.335 345.488 431.910 1.00 121.91 ? 222 VAL C CA  1 
ATOM 6846 C C   . VAL E 5 222 ? 360.526 344.677 431.424 1.00 121.91 ? 222 VAL C C   1 
ATOM 6847 O O   . VAL E 5 222 ? 360.462 343.957 430.425 1.00 121.91 ? 222 VAL C O   1 
ATOM 6848 C CB  . VAL E 5 222 ? 358.621 344.773 433.066 1.00 121.91 ? 222 VAL C CB  1 
ATOM 6849 C CG1 . VAL E 5 222 ? 357.618 345.698 433.682 1.00 121.91 ? 222 VAL C CG1 1 
ATOM 6850 C CG2 . VAL E 5 222 ? 357.933 343.535 432.550 1.00 121.91 ? 222 VAL C CG2 1 
ATOM 6851 N N   . ARG E 5 223 ? 361.626 344.794 432.165 1.00 123.93 ? 223 ARG C N   1 
ATOM 6852 C CA  . ARG E 5 223 ? 362.894 344.188 431.795 1.00 123.93 ? 223 ARG C CA  1 
ATOM 6853 C C   . ARG E 5 223 ? 363.792 344.184 433.025 1.00 123.93 ? 223 ARG C C   1 
ATOM 6854 O O   . ARG E 5 223 ? 363.611 345.009 433.924 1.00 123.93 ? 223 ARG C O   1 
ATOM 6855 C CB  . ARG E 5 223 ? 363.536 344.954 430.631 1.00 123.93 ? 223 ARG C CB  1 
ATOM 6856 C CG  . ARG E 5 223 ? 364.583 344.188 429.856 1.00 123.93 ? 223 ARG C CG  1 
ATOM 6857 C CD  . ARG E 5 223 ? 364.886 344.849 428.522 1.00 123.93 ? 223 ARG C CD  1 
ATOM 6858 N NE  . ARG E 5 223 ? 365.511 346.156 428.668 1.00 123.93 ? 223 ARG C NE  1 
ATOM 6859 C CZ  . ARG E 5 223 ? 364.948 347.291 428.278 1.00 123.93 ? 223 ARG C CZ  1 
ATOM 6860 N NH1 . ARG E 5 223 ? 363.747 347.275 427.722 1.00 123.93 ? 223 ARG C NH1 1 
ATOM 6861 N NH2 . ARG E 5 223 ? 365.582 348.440 428.443 1.00 123.93 ? 223 ARG C NH2 1 
ATOM 6862 N N   . MET E 5 224 ? 364.749 343.244 433.053 1.00 125.54 ? 224 MET C N   1 
ATOM 6863 C CA  . MET E 5 224 ? 365.755 343.099 434.116 1.00 125.54 ? 224 MET C CA  1 
ATOM 6864 C C   . MET E 5 224 ? 365.092 342.840 435.474 1.00 125.54 ? 224 MET C C   1 
ATOM 6865 O O   . MET E 5 224 ? 364.953 343.725 436.318 1.00 125.54 ? 224 MET C O   1 
ATOM 6866 C CB  . MET E 5 224 ? 366.704 344.306 434.168 1.00 125.54 ? 224 MET C CB  1 
ATOM 6867 C CG  . MET E 5 224 ? 367.904 344.149 435.100 1.00 125.54 ? 224 MET C CG  1 
ATOM 6868 S SD  . MET E 5 224 ? 369.041 342.872 434.556 1.00 125.54 ? 224 MET C SD  1 
ATOM 6869 C CE  . MET E 5 224 ? 369.783 343.697 433.154 1.00 125.54 ? 224 MET C CE  1 
ATOM 6870 N N   . LEU E 5 225 ? 364.578 341.617 435.602 1.00 117.69 ? 225 LEU C N   1 
ATOM 6871 C CA  . LEU E 5 225 ? 363.977 341.158 436.850 1.00 117.69 ? 225 LEU C CA  1 
ATOM 6872 C C   . LEU E 5 225 ? 364.973 341.192 438.005 1.00 117.69 ? 225 LEU C C   1 
ATOM 6873 O O   . LEU E 5 225 ? 366.159 340.906 437.837 1.00 117.69 ? 225 LEU C O   1 
ATOM 6874 C CB  . LEU E 5 225 ? 363.428 339.741 436.666 1.00 117.69 ? 225 LEU C CB  1 
ATOM 6875 C CG  . LEU E 5 225 ? 362.582 339.076 437.755 1.00 117.69 ? 225 LEU C CG  1 
ATOM 6876 C CD1 . LEU E 5 225 ? 361.533 338.232 437.096 1.00 117.69 ? 225 LEU C CD1 1 
ATOM 6877 C CD2 . LEU E 5 225 ? 363.412 338.190 438.659 1.00 117.69 ? 225 LEU C CD2 1 
ATOM 6878 N N   . LYS E 5 226 ? 364.472 341.544 439.186 1.00 116.10 ? 226 LYS C N   1 
ATOM 6879 C CA  . LYS E 5 226 ? 365.243 341.529 440.418 1.00 116.10 ? 226 LYS C CA  1 
ATOM 6880 C C   . LYS E 5 226 ? 364.341 340.993 441.520 1.00 116.10 ? 226 LYS C C   1 
ATOM 6881 O O   . LYS E 5 226 ? 363.190 340.624 441.274 1.00 116.10 ? 226 LYS C O   1 
ATOM 6882 C CB  . LYS E 5 226 ? 365.788 342.923 440.746 1.00 116.10 ? 226 LYS C CB  1 
ATOM 6883 C CG  . LYS E 5 226 ? 364.743 343.918 441.221 1.00 116.10 ? 226 LYS C CG  1 
ATOM 6884 C CD  . LYS E 5 226 ? 365.396 345.029 442.016 1.00 116.10 ? 226 LYS C CD  1 
ATOM 6885 C CE  . LYS E 5 226 ? 364.584 346.301 441.975 1.00 116.10 ? 226 LYS C CE  1 
ATOM 6886 N NZ  . LYS E 5 226 ? 363.260 346.124 442.609 1.00 116.10 ? 226 LYS C NZ  1 
ATOM 6887 N N   . ASP E 5 227 ? 364.858 340.938 442.741 1.00 123.06 ? 227 ASP C N   1 
ATOM 6888 C CA  . ASP E 5 227 ? 364.046 340.513 443.870 1.00 123.06 ? 227 ASP C CA  1 
ATOM 6889 C C   . ASP E 5 227 ? 363.360 341.710 444.520 1.00 123.06 ? 227 ASP C C   1 
ATOM 6890 O O   . ASP E 5 227 ? 363.754 342.861 444.330 1.00 123.06 ? 227 ASP C O   1 
ATOM 6891 C CB  . ASP E 5 227 ? 364.890 339.754 444.892 1.00 123.06 ? 227 ASP C CB  1 
ATOM 6892 C CG  . ASP E 5 227 ? 366.092 340.544 445.373 1.00 123.06 ? 227 ASP C CG  1 
ATOM 6893 O OD1 . ASP E 5 227 ? 366.395 341.613 444.802 1.00 123.06 ? 227 ASP C OD1 1 
ATOM 6894 O OD2 . ASP E 5 227 ? 366.766 340.066 446.309 1.00 123.06 ? 227 ASP C OD2 1 
ATOM 6895 N N   . THR E 5 228 ? 362.348 341.426 445.286 1.00 117.77 ? 228 THR C N   1 
ATOM 6896 C CA  . THR E 5 228 ? 361.543 342.511 445.820 1.00 117.77 ? 228 THR C CA  1 
ATOM 6897 C C   . THR E 5 228 ? 362.163 343.088 447.088 1.00 117.77 ? 228 THR C C   1 
ATOM 6898 O O   . THR E 5 228 ? 362.799 342.366 447.862 1.00 117.77 ? 228 THR C O   1 
ATOM 6899 C CB  . THR E 5 228 ? 360.127 342.021 446.112 1.00 117.77 ? 228 THR C CB  1 
ATOM 6900 O OG1 . THR E 5 228 ? 359.411 343.018 446.849 1.00 117.77 ? 228 THR C OG1 1 
ATOM 6901 C CG2 . THR E 5 228 ? 360.151 340.716 446.891 1.00 117.77 ? 228 THR C CG2 1 
ATOM 6902 N N   . PRO E 5 229 ? 362.026 344.393 447.316 1.00 115.11 ? 229 PRO C N   1 
ATOM 6903 C CA  . PRO E 5 229 ? 362.529 345.000 448.555 1.00 115.11 ? 229 PRO C CA  1 
ATOM 6904 C C   . PRO E 5 229 ? 361.541 345.022 449.713 1.00 115.11 ? 229 PRO C C   1 
ATOM 6905 O O   . PRO E 5 229 ? 361.860 345.613 450.748 1.00 115.11 ? 229 PRO C O   1 
ATOM 6906 C CB  . PRO E 5 229 ? 362.845 346.431 448.106 1.00 115.11 ? 229 PRO C CB  1 
ATOM 6907 C CG  . PRO E 5 229 ? 361.843 346.703 447.071 1.00 115.11 ? 229 PRO C CG  1 
ATOM 6908 C CD  . PRO E 5 229 ? 361.652 345.416 446.325 1.00 115.11 ? 229 PRO C CD  1 
ATOM 6909 N N   . PHE E 5 230 ? 360.368 344.411 449.576 1.00 116.30 ? 230 PHE C N   1 
ATOM 6910 C CA  . PHE E 5 230 ? 359.378 344.385 450.651 1.00 116.30 ? 230 PHE C CA  1 
ATOM 6911 C C   . PHE E 5 230 ? 359.511 343.089 451.448 1.00 116.30 ? 230 PHE C C   1 
ATOM 6912 O O   . PHE E 5 230 ? 358.570 342.312 451.605 1.00 116.30 ? 230 PHE C O   1 
ATOM 6913 C CB  . PHE E 5 230 ? 357.974 344.544 450.081 1.00 116.30 ? 230 PHE C CB  1 
ATOM 6914 C CG  . PHE E 5 230 ? 357.761 345.830 449.352 1.00 116.30 ? 230 PHE C CG  1 
ATOM 6915 C CD1 . PHE E 5 230 ? 358.321 347.003 449.821 1.00 116.30 ? 230 PHE C CD1 1 
ATOM 6916 C CD2 . PHE E 5 230 ? 356.999 345.868 448.199 1.00 116.30 ? 230 PHE C CD2 1 
ATOM 6917 C CE1 . PHE E 5 230 ? 358.125 348.190 449.153 1.00 116.30 ? 230 PHE C CE1 1 
ATOM 6918 C CE2 . PHE E 5 230 ? 356.801 347.051 447.527 1.00 116.30 ? 230 PHE C CE2 1 
ATOM 6919 C CZ  . PHE E 5 230 ? 357.363 348.213 448.006 1.00 116.30 ? 230 PHE C CZ  1 
ATOM 6920 N N   . ILE E 5 231 ? 360.718 342.870 451.963 1.00 126.53 ? 231 ILE C N   1 
ATOM 6921 C CA  . ILE E 5 231 ? 361.035 341.650 452.694 1.00 126.53 ? 231 ILE C CA  1 
ATOM 6922 C C   . ILE E 5 231 ? 362.171 341.975 453.653 1.00 126.53 ? 231 ILE C C   1 
ATOM 6923 O O   . ILE E 5 231 ? 362.811 343.023 453.543 1.00 126.53 ? 231 ILE C O   1 
ATOM 6924 C CB  . ILE E 5 231 ? 361.386 340.497 451.719 1.00 126.53 ? 231 ILE C CB  1 
ATOM 6925 C CG1 . ILE E 5 231 ? 360.926 339.161 452.294 1.00 126.53 ? 231 ILE C CG1 1 
ATOM 6926 C CG2 . ILE E 5 231 ? 362.869 340.490 451.367 1.00 126.53 ? 231 ILE C CG2 1 
ATOM 6927 C CD1 . ILE E 5 231 ? 359.426 339.043 452.376 1.00 126.53 ? 231 ILE C CD1 1 
ATOM 6928 N N   . ARG E 5 232 ? 362.394 341.092 454.627 1.00 139.74 ? 232 ARG C N   1 
ATOM 6929 C CA  . ARG E 5 232 ? 363.391 341.301 455.679 1.00 139.74 ? 232 ARG C CA  1 
ATOM 6930 C C   . ARG E 5 232 ? 364.820 341.406 455.145 1.00 139.74 ? 232 ARG C C   1 
ATOM 6931 O O   . ARG E 5 232 ? 365.146 340.846 454.098 1.00 139.74 ? 232 ARG C O   1 
ATOM 6932 C CB  . ARG E 5 232 ? 363.307 340.170 456.710 1.00 139.74 ? 232 ARG C CB  1 
ATOM 6933 C CG  . ARG E 5 232 ? 363.547 338.772 456.147 1.00 139.74 ? 232 ARG C CG  1 
ATOM 6934 C CD  . ARG E 5 232 ? 364.923 338.240 456.542 1.00 139.74 ? 232 ARG C CD  1 
ATOM 6935 N NE  . ARG E 5 232 ? 365.153 336.878 456.076 1.00 139.74 ? 232 ARG C NE  1 
ATOM 6936 C CZ  . ARG E 5 232 ? 366.330 336.263 456.128 1.00 139.74 ? 232 ARG C CZ  1 
ATOM 6937 N NH1 . ARG E 5 232 ? 367.386 336.893 456.623 1.00 139.74 ? 232 ARG C NH1 1 
ATOM 6938 N NH2 . ARG E 5 232 ? 366.452 335.021 455.682 1.00 139.74 ? 232 ARG C NH2 1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   1   1   ASP ASP L . n 
A 1 2   ILE 2   2   2   ILE ILE L . n 
A 1 3   GLN 3   3   3   GLN GLN L . n 
A 1 4   MET 4   4   4   MET MET L . n 
A 1 5   THR 5   5   5   THR THR L . n 
A 1 6   GLN 6   6   6   GLN GLN L . n 
A 1 7   SER 7   7   7   SER SER L . n 
A 1 8   PRO 8   8   8   PRO PRO L . n 
A 1 9   ALA 9   9   9   ALA ALA L . n 
A 1 10  SER 10  10  10  SER SER L . n 
A 1 11  LEU 11  11  11  LEU LEU L . n 
A 1 12  SER 12  12  12  SER SER L . n 
A 1 13  VAL 13  13  13  VAL VAL L . n 
A 1 14  SER 14  14  14  SER SER L . n 
A 1 15  VAL 15  15  15  VAL VAL L . n 
A 1 16  GLY 16  16  16  GLY GLY L . n 
A 1 17  GLU 17  17  17  GLU GLU L . n 
A 1 18  THR 18  18  18  THR THR L . n 
A 1 19  VAL 19  19  19  VAL VAL L . n 
A 1 20  THR 20  20  20  THR THR L . n 
A 1 21  ILE 21  21  21  ILE ILE L . n 
A 1 22  THR 22  22  22  THR THR L . n 
A 1 23  CYS 23  23  23  CYS CYS L . n 
A 1 24  ARG 24  24  24  ARG ARG L . n 
A 1 25  ALA 25  25  25  ALA ALA L . n 
A 1 26  SER 26  26  26  SER SER L . n 
A 1 27  GLU 27  27  27  GLU GLU L . n 
A 1 28  ASN 28  28  28  ASN ASN L . n 
A 1 29  VAL 29  29  29  VAL VAL L . n 
A 1 30  TYR 30  30  30  TYR TYR L . n 
A 1 31  ARG 31  31  31  ARG ARG L . n 
A 1 32  ASN 32  32  32  ASN ASN L . n 
A 1 33  LEU 33  33  33  LEU LEU L . n 
A 1 34  ALA 34  34  34  ALA ALA L . n 
A 1 35  TRP 35  35  35  TRP TRP L . n 
A 1 36  TYR 36  36  36  TYR TYR L . n 
A 1 37  GLN 37  37  37  GLN GLN L . n 
A 1 38  GLN 38  38  38  GLN GLN L . n 
A 1 39  LYS 39  39  39  LYS LYS L . n 
A 1 40  GLN 40  40  40  GLN GLN L . n 
A 1 41  GLY 41  41  41  GLY GLY L . n 
A 1 42  LYS 42  42  42  LYS LYS L . n 
A 1 43  SER 43  43  43  SER SER L . n 
A 1 44  PRO 44  44  44  PRO PRO L . n 
A 1 45  GLN 45  45  45  GLN GLN L . n 
A 1 46  LEU 46  46  46  LEU LEU L . n 
A 1 47  LEU 47  47  47  LEU LEU L . n 
A 1 48  VAL 48  48  48  VAL VAL L . n 
A 1 49  TYR 49  49  49  TYR TYR L . n 
A 1 50  ALA 50  50  50  ALA ALA L . n 
A 1 51  ALA 51  51  51  ALA ALA L . n 
A 1 52  THR 52  52  52  THR THR L . n 
A 1 53  ASN 53  53  53  ASN ASN L . n 
A 1 54  LEU 54  54  54  LEU LEU L . n 
A 1 55  ALA 55  55  55  ALA ALA L . n 
A 1 56  ASP 56  56  56  ASP ASP L . n 
A 1 57  GLY 57  57  57  GLY GLY L . n 
A 1 58  VAL 58  58  58  VAL VAL L . n 
A 1 59  PRO 59  59  59  PRO PRO L . n 
A 1 60  SER 60  60  60  SER SER L . n 
A 1 61  ARG 61  61  61  ARG ARG L . n 
A 1 62  PHE 62  62  62  PHE PHE L . n 
A 1 63  SER 63  63  63  SER SER L . n 
A 1 64  GLY 64  64  64  GLY GLY L . n 
A 1 65  SER 65  65  65  SER SER L . n 
A 1 66  GLY 66  66  66  GLY GLY L . n 
A 1 67  SER 67  67  67  SER SER L . n 
A 1 68  GLY 68  68  68  GLY GLY L . n 
A 1 69  THR 69  69  69  THR THR L . n 
A 1 70  GLN 70  70  70  GLN GLN L . n 
A 1 71  TYR 71  71  71  TYR TYR L . n 
A 1 72  SER 72  72  72  SER SER L . n 
A 1 73  LEU 73  73  73  LEU LEU L . n 
A 1 74  LYS 74  74  74  LYS LYS L . n 
A 1 75  ILE 75  75  75  ILE ILE L . n 
A 1 76  ASN 76  76  76  ASN ASN L . n 
A 1 77  SER 77  77  77  SER SER L . n 
A 1 78  LEU 78  78  78  LEU LEU L . n 
A 1 79  GLN 79  79  79  GLN GLN L . n 
A 1 80  SER 80  80  80  SER SER L . n 
A 1 81  GLU 81  81  81  GLU GLU L . n 
A 1 82  ASP 82  82  82  ASP ASP L . n 
A 1 83  PHE 83  83  83  PHE PHE L . n 
A 1 84  GLY 84  84  84  GLY GLY L . n 
A 1 85  SER 85  85  85  SER SER L . n 
A 1 86  TYR 86  86  86  TYR TYR L . n 
A 1 87  PHE 87  87  87  PHE PHE L . n 
A 1 88  CYS 88  88  88  CYS CYS L . n 
A 1 89  GLN 89  89  89  GLN GLN L . n 
A 1 90  HIS 90  90  90  HIS HIS L . n 
A 1 91  PHE 91  91  91  PHE PHE L . n 
A 1 92  TRP 92  92  92  TRP TRP L . n 
A 1 93  SER 93  93  93  SER SER L . n 
A 1 94  PRO 94  94  94  PRO PRO L . n 
A 1 95  VAL 95  95  95  VAL VAL L . n 
A 1 96  PHE 96  96  96  PHE PHE L . n 
A 1 97  THR 97  97  97  THR THR L . n 
A 1 98  PHE 98  98  98  PHE PHE L . n 
A 1 99  GLY 99  99  99  GLY GLY L . n 
A 1 100 ALA 100 100 100 ALA ALA L . n 
A 1 101 GLY 101 101 101 GLY GLY L . n 
A 1 102 THR 102 102 102 THR THR L . n 
A 1 103 LYS 103 103 103 LYS LYS L . n 
A 1 104 LEU 104 104 104 LEU LEU L . n 
A 1 105 GLU 105 105 105 GLU GLU L . n 
A 1 106 LEU 106 106 106 LEU LEU L . n 
A 1 107 LYS 107 107 107 LYS LYS L . n 
B 2 1   GLN 1   1   1   GLN GLN H . n 
B 2 2   VAL 2   2   2   VAL VAL H . n 
B 2 3   GLN 3   3   3   GLN GLN H . n 
B 2 4   LEU 4   4   4   LEU LEU H . n 
B 2 5   LYS 5   5   5   LYS LYS H . n 
B 2 6   GLN 6   6   6   GLN GLN H . n 
B 2 7   SER 7   7   7   SER SER H . n 
B 2 8   GLY 8   8   8   GLY GLY H . n 
B 2 9   PRO 9   9   9   PRO PRO H . n 
B 2 10  GLY 10  10  10  GLY GLY H . n 
B 2 11  LEU 11  11  11  LEU LEU H . n 
B 2 12  VAL 12  12  12  VAL VAL H . n 
B 2 13  GLN 13  13  13  GLN GLN H . n 
B 2 14  PRO 14  14  14  PRO PRO H . n 
B 2 15  SER 15  15  15  SER SER H . n 
B 2 16  GLN 16  16  16  GLN GLN H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  LEU 18  18  18  LEU LEU H . n 
B 2 19  SER 19  19  19  SER SER H . n 
B 2 20  ILE 20  20  20  ILE ILE H . n 
B 2 21  THR 21  21  21  THR THR H . n 
B 2 22  CYS 22  22  22  CYS CYS H . n 
B 2 23  THR 23  23  23  THR THR H . n 
B 2 24  VAL 24  24  24  VAL VAL H . n 
B 2 25  SER 25  25  25  SER SER H . n 
B 2 26  GLY 26  26  26  GLY GLY H . n 
B 2 27  PHE 27  27  27  PHE PHE H . n 
B 2 28  SER 28  28  28  SER SER H . n 
B 2 29  LEU 29  29  29  LEU LEU H . n 
B 2 30  THR 30  30  30  THR THR H . n 
B 2 31  ASN 31  31  31  ASN ASN H . n 
B 2 32  TYR 32  32  32  TYR TYR H . n 
B 2 33  GLY 33  33  33  GLY GLY H . n 
B 2 34  VAL 34  34  34  VAL VAL H . n 
B 2 35  HIS 35  35  35  HIS HIS H . n 
B 2 36  TRP 36  36  36  TRP TRP H . n 
B 2 37  VAL 37  37  37  VAL VAL H . n 
B 2 38  ARG 38  38  38  ARG ARG H . n 
B 2 39  GLN 39  39  39  GLN GLN H . n 
B 2 40  SER 40  40  40  SER SER H . n 
B 2 41  PRO 41  41  41  PRO PRO H . n 
B 2 42  GLY 42  42  42  GLY GLY H . n 
B 2 43  LYS 43  43  43  LYS LYS H . n 
B 2 44  GLY 44  44  44  GLY GLY H . n 
B 2 45  LEU 45  45  45  LEU LEU H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  TRP 47  47  47  TRP TRP H . n 
B 2 48  LEU 48  48  48  LEU LEU H . n 
B 2 49  GLY 49  49  49  GLY GLY H . n 
B 2 50  VAL 50  50  50  VAL VAL H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  TRP 52  52  52  TRP TRP H . n 
B 2 53  ARG 53  53  53  ARG ARG H . n 
B 2 54  GLY 54  54  54  GLY GLY H . n 
B 2 55  GLY 55  55  55  GLY GLY H . n 
B 2 56  SER 56  56  56  SER SER H . n 
B 2 57  THR 57  57  57  THR THR H . n 
B 2 58  ASP 58  58  58  ASP ASP H . n 
B 2 59  TYR 59  59  59  TYR TYR H . n 
B 2 60  ASN 60  60  60  ASN ASN H . n 
B 2 61  ALA 61  61  61  ALA ALA H . n 
B 2 62  ALA 62  62  62  ALA ALA H . n 
B 2 63  PHE 63  63  63  PHE PHE H . n 
B 2 64  MET 64  64  64  MET MET H . n 
B 2 65  SER 65  65  65  SER SER H . n 
B 2 66  ARG 66  66  66  ARG ARG H . n 
B 2 67  LEU 67  67  67  LEU LEU H . n 
B 2 68  SER 68  68  68  SER SER H . n 
B 2 69  ILE 69  69  69  ILE ILE H . n 
B 2 70  THR 70  70  70  THR THR H . n 
B 2 71  LYS 71  71  71  LYS LYS H . n 
B 2 72  ASP 72  72  72  ASP ASP H . n 
B 2 73  ASN 73  73  73  ASN ASN H . n 
B 2 74  SER 74  74  74  SER SER H . n 
B 2 75  LYS 75  75  75  LYS LYS H . n 
B 2 76  SER 76  76  76  SER SER H . n 
B 2 77  GLN 77  77  77  GLN GLN H . n 
B 2 78  VAL 78  78  78  VAL VAL H . n 
B 2 79  PHE 79  79  79  PHE PHE H . n 
B 2 80  PHE 80  80  80  PHE PHE H . n 
B 2 81  LYS 81  81  81  LYS LYS H . n 
B 2 82  MET 82  82  82  MET MET H . n 
B 2 83  ASN 83  83  83  ASN ASN H . n 
B 2 84  SER 84  84  84  SER SER H . n 
B 2 85  LEU 85  85  85  LEU LEU H . n 
B 2 86  GLN 86  86  86  GLN GLN H . n 
B 2 87  ALA 87  87  87  ALA ALA H . n 
B 2 88  ASP 88  88  88  ASP ASP H . n 
B 2 89  ASP 89  89  89  ASP ASP H . n 
B 2 90  THR 90  90  90  THR THR H . n 
B 2 91  ALA 91  91  91  ALA ALA H . n 
B 2 92  ILE 92  92  92  ILE ILE H . n 
B 2 93  TYR 93  93  93  TYR TYR H . n 
B 2 94  TYR 94  94  94  TYR TYR H . n 
B 2 95  CYS 95  95  95  CYS CYS H . n 
B 2 96  ALA 96  96  96  ALA ALA H . n 
B 2 97  LYS 97  97  97  LYS LYS H . n 
B 2 98  GLY 98  98  98  GLY GLY H . n 
B 2 99  ASP 99  99  99  ASP ASP H . n 
B 2 100 TYR 100 100 100 TYR TYR H . n 
B 2 101 TYR 101 101 101 TYR TYR H . n 
B 2 102 GLY 102 102 102 GLY GLY H . n 
B 2 103 TYR 103 103 103 TYR TYR H . n 
B 2 104 ASP 104 104 104 ASP ASP H . n 
B 2 105 ALA 105 105 105 ALA ALA H . n 
B 2 106 MET 106 106 106 MET MET H . n 
B 2 107 ASP 107 107 107 ASP ASP H . n 
B 2 108 SER 108 108 108 SER SER H . n 
B 2 109 TRP 109 109 109 TRP TRP H . n 
B 2 110 GLY 110 110 110 GLY GLY H . n 
B 2 111 GLN 111 111 111 GLN GLN H . n 
B 2 112 GLY 112 112 112 GLY GLY H . n 
B 2 113 THR 113 113 113 THR THR H . n 
B 2 114 SER 114 114 114 SER SER H . n 
B 2 115 VAL 115 115 115 VAL VAL H . n 
B 2 116 THR 116 116 116 THR THR H . n 
B 2 117 VAL 117 117 117 VAL VAL H . n 
B 2 118 SER 118 118 118 SER SER H . n 
B 2 119 ARG 119 119 119 ARG ARG H . n 
C 3 1   GLY 1   1   ?   ?   ?   A . n 
C 3 2   PRO 2   2   ?   ?   ?   A . n 
C 3 3   VAL 3   3   ?   ?   ?   A . n 
C 3 4   GLU 4   4   ?   ?   ?   A . n 
C 3 5   GLU 5   5   ?   ?   ?   A . n 
C 3 6   SER 6   6   ?   ?   ?   A . n 
C 3 7   VAL 7   7   ?   ?   ?   A . n 
C 3 8   ASP 8   8   ?   ?   ?   A . n 
C 3 9   ARG 9   9   ?   ?   ?   A . n 
C 3 10  ALA 10  10  ?   ?   ?   A . n 
C 3 11  VAL 11  11  ?   ?   ?   A . n 
C 3 12  ALA 12  12  ?   ?   ?   A . n 
C 3 13  ARG 13  13  ?   ?   ?   A . n 
C 3 14  VAL 14  14  ?   ?   ?   A . n 
C 3 15  ALA 15  15  ?   ?   ?   A . n 
C 3 16  ASP 16  16  ?   ?   ?   A . n 
C 3 17  THR 17  17  ?   ?   ?   A . n 
C 3 18  ILE 18  18  ?   ?   ?   A . n 
C 3 19  SER 19  19  ?   ?   ?   A . n 
C 3 20  SER 20  20  ?   ?   ?   A . n 
C 3 21  ARG 21  21  ?   ?   ?   A . n 
C 3 22  PRO 22  22  ?   ?   ?   A . n 
C 3 23  THR 23  23  ?   ?   ?   A . n 
C 3 24  ASN 24  24  ?   ?   ?   A . n 
C 3 25  SER 25  25  ?   ?   ?   A . n 
C 3 26  GLU 26  26  ?   ?   ?   A . n 
C 3 27  SER 27  27  ?   ?   ?   A . n 
C 3 28  ILE 28  28  ?   ?   ?   A . n 
C 3 29  PRO 29  29  ?   ?   ?   A . n 
C 3 30  ALA 30  30  ?   ?   ?   A . n 
C 3 31  LEU 31  31  ?   ?   ?   A . n 
C 3 32  THR 32  32  ?   ?   ?   A . n 
C 3 33  ALA 33  33  ?   ?   ?   A . n 
C 3 34  ALA 34  34  ?   ?   ?   A . n 
C 3 35  GLU 35  35  ?   ?   ?   A . n 
C 3 36  THR 36  36  ?   ?   ?   A . n 
C 3 37  GLY 37  37  ?   ?   ?   A . n 
C 3 38  HIS 38  38  ?   ?   ?   A . n 
C 3 39  THR 39  39  ?   ?   ?   A . n 
C 3 40  SER 40  40  ?   ?   ?   A . n 
C 3 41  GLN 41  41  ?   ?   ?   A . n 
C 3 42  VAL 42  42  ?   ?   ?   A . n 
C 3 43  VAL 43  43  ?   ?   ?   A . n 
C 3 44  PRO 44  44  ?   ?   ?   A . n 
C 3 45  SER 45  45  ?   ?   ?   A . n 
C 3 46  ASP 46  46  ?   ?   ?   A . n 
C 3 47  THR 47  47  ?   ?   ?   A . n 
C 3 48  MET 48  48  ?   ?   ?   A . n 
C 3 49  GLN 49  49  ?   ?   ?   A . n 
C 3 50  THR 50  50  ?   ?   ?   A . n 
C 3 51  ARG 51  51  ?   ?   ?   A . n 
C 3 52  HIS 52  52  ?   ?   ?   A . n 
C 3 53  VAL 53  53  ?   ?   ?   A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ASN 55  55  ?   ?   ?   A . n 
C 3 56  TYR 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  SER 58  58  58  SER SER A . n 
C 3 59  ARG 59  59  59  ARG ARG A . n 
C 3 60  SER 60  60  60  SER SER A . n 
C 3 61  GLU 61  61  61  GLU GLU A . n 
C 3 62  SER 62  62  62  SER SER A . n 
C 3 63  SER 63  63  63  SER SER A . n 
C 3 64  ILE 64  64  64  ILE ILE A . n 
C 3 65  GLU 65  65  65  GLU GLU A . n 
C 3 66  ASN 66  66  66  ASN ASN A . n 
C 3 67  PHE 67  67  67  PHE PHE A . n 
C 3 68  LEU 68  68  68  LEU LEU A . n 
C 3 69  CYS 69  69  69  CYS CYS A . n 
C 3 70  ARG 70  70  70  ARG ARG A . n 
C 3 71  SER 71  71  71  SER SER A . n 
C 3 72  ALA 72  72  72  ALA ALA A . n 
C 3 73  CYS 73  73  73  CYS CYS A . n 
C 3 74  VAL 74  74  74  VAL VAL A . n 
C 3 75  TYR 75  75  75  TYR TYR A . n 
C 3 76  TYR 76  76  76  TYR TYR A . n 
C 3 77  ALA 77  77  77  ALA ALA A . n 
C 3 78  THR 78  78  78  THR THR A . n 
C 3 79  TYR 79  79  79  TYR TYR A . n 
C 3 80  THR 80  80  80  THR THR A . n 
C 3 81  ASN 81  81  81  ASN ASN A . n 
C 3 82  ASN 82  82  82  ASN ASN A . n 
C 3 83  SER 83  83  83  SER SER A . n 
C 3 84  LYS 84  84  84  LYS LYS A . n 
C 3 85  LYS 85  85  85  LYS LYS A . n 
C 3 86  GLY 86  86  86  GLY GLY A . n 
C 3 87  PHE 87  87  87  PHE PHE A . n 
C 3 88  ALA 88  88  88  ALA ALA A . n 
C 3 89  GLU 89  89  89  GLU GLU A . n 
C 3 90  TRP 90  90  90  TRP TRP A . n 
C 3 91  VAL 91  91  91  VAL VAL A . n 
C 3 92  ILE 92  92  92  ILE ILE A . n 
C 3 93  ASN 93  93  93  ASN ASN A . n 
C 3 94  THR 94  94  94  THR THR A . n 
C 3 95  ARG 95  95  95  ARG ARG A . n 
C 3 96  GLN 96  96  96  GLN GLN A . n 
C 3 97  VAL 97  97  97  VAL VAL A . n 
C 3 98  ALA 98  98  98  ALA ALA A . n 
C 3 99  GLN 99  99  99  GLN GLN A . n 
C 3 100 LEU 100 100 100 LEU LEU A . n 
C 3 101 ARG 101 101 101 ARG ARG A . n 
C 3 102 ARG 102 102 102 ARG ARG A . n 
C 3 103 LYS 103 103 103 LYS LYS A . n 
C 3 104 LEU 104 104 104 LEU LEU A . n 
C 3 105 GLU 105 105 105 GLU GLU A . n 
C 3 106 LEU 106 106 106 LEU LEU A . n 
C 3 107 PHE 107 107 107 PHE PHE A . n 
C 3 108 THR 108 108 108 THR THR A . n 
C 3 109 TYR 109 109 109 TYR TYR A . n 
C 3 110 LEU 110 110 110 LEU LEU A . n 
C 3 111 ARG 111 111 111 ARG ARG A . n 
C 3 112 PHE 112 112 112 PHE PHE A . n 
C 3 113 ASP 113 113 113 ASP ASP A . n 
C 3 114 LEU 114 114 114 LEU LEU A . n 
C 3 115 GLU 115 115 115 GLU GLU A . n 
C 3 116 LEU 116 116 116 LEU LEU A . n 
C 3 117 THR 117 117 117 THR THR A . n 
C 3 118 PHE 118 118 118 PHE PHE A . n 
C 3 119 VAL 119 119 119 VAL VAL A . n 
C 3 120 ILE 120 120 120 ILE ILE A . n 
C 3 121 THR 121 121 121 THR THR A . n 
C 3 122 SER 122 122 122 SER SER A . n 
C 3 123 ALA 123 123 123 ALA ALA A . n 
C 3 124 GLN 124 124 124 GLN GLN A . n 
C 3 125 GLN 125 125 125 GLN GLN A . n 
C 3 126 PRO 126 126 126 PRO PRO A . n 
C 3 127 SER 127 127 127 SER SER A . n 
C 3 128 THR 128 128 128 THR THR A . n 
C 3 129 ALA 129 129 129 ALA ALA A . n 
C 3 130 SER 130 130 130 SER SER A . n 
C 3 131 SER 131 131 131 SER SER A . n 
C 3 132 VAL 132 132 132 VAL VAL A . n 
C 3 133 ASP 133 133 133 ASP ASP A . n 
C 3 134 ALA 134 134 134 ALA ALA A . n 
C 3 135 PRO 135 135 135 PRO PRO A . n 
C 3 136 VAL 136 136 136 VAL VAL A . n 
C 3 137 GLN 137 137 137 GLN GLN A . n 
C 3 138 THR 138 138 138 THR THR A . n 
C 3 139 HIS 139 139 139 HIS HIS A . n 
C 3 140 GLN 140 140 140 GLN GLN A . n 
C 3 141 ILE 141 141 141 ILE ILE A . n 
C 3 142 MET 142 142 142 MET MET A . n 
C 3 143 TYR 143 143 143 TYR TYR A . n 
C 3 144 VAL 144 144 144 VAL VAL A . n 
C 3 145 PRO 145 145 145 PRO PRO A . n 
C 3 146 PRO 146 146 146 PRO PRO A . n 
C 3 147 GLY 147 147 147 GLY GLY A . n 
C 3 148 GLY 148 148 148 GLY GLY A . n 
C 3 149 PRO 149 149 149 PRO PRO A . n 
C 3 150 VAL 150 150 150 VAL VAL A . n 
C 3 151 PRO 151 151 151 PRO PRO A . n 
C 3 152 THR 152 152 152 THR THR A . n 
C 3 153 LYS 153 153 153 LYS LYS A . n 
C 3 154 VAL 154 154 154 VAL VAL A . n 
C 3 155 LYS 155 155 155 LYS LYS A . n 
C 3 156 ASP 156 156 156 ASP ASP A . n 
C 3 157 TYR 157 157 157 TYR TYR A . n 
C 3 158 ALA 158 158 158 ALA ALA A . n 
C 3 159 TRP 159 159 159 TRP TRP A . n 
C 3 160 GLN 160 160 160 GLN GLN A . n 
C 3 161 THR 161 161 161 THR THR A . n 
C 3 162 SER 162 162 162 SER SER A . n 
C 3 163 THR 163 163 163 THR THR A . n 
C 3 164 ASN 164 164 164 ASN ASN A . n 
C 3 165 PRO 165 165 165 PRO PRO A . n 
C 3 166 SER 166 166 166 SER SER A . n 
C 3 167 VAL 167 167 167 VAL VAL A . n 
C 3 168 PHE 168 168 168 PHE PHE A . n 
C 3 169 TRP 169 169 169 TRP TRP A . n 
C 3 170 THR 170 170 170 THR THR A . n 
C 3 171 GLU 171 171 171 GLU GLU A . n 
C 3 172 GLY 172 172 172 GLY GLY A . n 
C 3 173 ASN 173 173 173 ASN ASN A . n 
C 3 174 ALA 174 174 174 ALA ALA A . n 
C 3 175 PRO 175 175 175 PRO PRO A . n 
C 3 176 PRO 176 176 176 PRO PRO A . n 
C 3 177 ARG 177 177 177 ARG ARG A . n 
C 3 178 MET 178 178 178 MET MET A . n 
C 3 179 SER 179 179 179 SER SER A . n 
C 3 180 ILE 180 180 180 ILE ILE A . n 
C 3 181 PRO 181 181 181 PRO PRO A . n 
C 3 182 PHE 182 182 182 PHE PHE A . n 
C 3 183 ILE 183 183 183 ILE ILE A . n 
C 3 184 SER 184 184 184 SER SER A . n 
C 3 185 ILE 185 185 185 ILE ILE A . n 
C 3 186 GLY 186 186 186 GLY GLY A . n 
C 3 187 ASN 187 187 187 ASN ASN A . n 
C 3 188 ALA 188 188 188 ALA ALA A . n 
C 3 189 TYR 189 189 189 TYR TYR A . n 
C 3 190 SER 190 190 190 SER SER A . n 
C 3 191 CYS 191 191 191 CYS CYS A . n 
C 3 192 PHE 192 192 192 PHE PHE A . n 
C 3 193 TYR 193 193 193 TYR TYR A . n 
C 3 194 ASP 194 194 194 ASP ASP A . n 
C 3 195 GLY 195 195 195 GLY GLY A . n 
C 3 196 TRP 196 196 196 TRP TRP A . n 
C 3 197 THR 197 197 197 THR THR A . n 
C 3 198 GLN 198 198 ?   ?   ?   A . n 
C 3 199 PHE 199 199 ?   ?   ?   A . n 
C 3 200 SER 200 200 ?   ?   ?   A . n 
C 3 201 ARG 201 201 ?   ?   ?   A . n 
C 3 202 ASN 202 202 ?   ?   ?   A . n 
C 3 203 GLY 203 203 ?   ?   ?   A . n 
C 3 204 VAL 204 204 204 VAL VAL A . n 
C 3 205 TYR 205 205 205 TYR TYR A . n 
C 3 206 GLY 206 206 206 GLY GLY A . n 
C 3 207 ILE 207 207 207 ILE ILE A . n 
C 3 208 ASN 208 208 208 ASN ASN A . n 
C 3 209 THR 209 209 209 THR THR A . n 
C 3 210 LEU 210 210 210 LEU LEU A . n 
C 3 211 ASN 211 211 211 ASN ASN A . n 
C 3 212 ASN 212 212 212 ASN ASN A . n 
C 3 213 MET 213 213 213 MET MET A . n 
C 3 214 GLY 214 214 214 GLY GLY A . n 
C 3 215 THR 215 215 215 THR THR A . n 
C 3 216 LEU 216 216 216 LEU LEU A . n 
C 3 217 TYR 217 217 217 TYR TYR A . n 
C 3 218 MET 218 218 218 MET MET A . n 
C 3 219 ARG 219 219 219 ARG ARG A . n 
C 3 220 HIS 220 220 220 HIS HIS A . n 
C 3 221 VAL 221 221 221 VAL VAL A . n 
C 3 222 ASN 222 222 222 ASN ASN A . n 
C 3 223 GLU 223 223 223 GLU GLU A . n 
C 3 224 ALA 224 224 224 ALA ALA A . n 
C 3 225 GLY 225 225 225 GLY GLY A . n 
C 3 226 GLN 226 226 226 GLN GLN A . n 
C 3 227 GLY 227 227 227 GLY GLY A . n 
C 3 228 PRO 228 228 228 PRO PRO A . n 
C 3 229 ILE 229 229 229 ILE ILE A . n 
C 3 230 LYS 230 230 230 LYS LYS A . n 
C 3 231 SER 231 231 231 SER SER A . n 
C 3 232 THR 232 232 232 THR THR A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 ARG 234 234 234 ARG ARG A . n 
C 3 235 ILE 235 235 235 ILE ILE A . n 
C 3 236 TYR 236 236 236 TYR TYR A . n 
C 3 237 PHE 237 237 237 PHE PHE A . n 
C 3 238 LYS 238 238 238 LYS LYS A . n 
C 3 239 PRO 239 239 239 PRO PRO A . n 
C 3 240 LYS 240 240 240 LYS LYS A . n 
C 3 241 HIS 241 241 241 HIS HIS A . n 
C 3 242 VAL 242 242 242 VAL VAL A . n 
C 3 243 LYS 243 243 243 LYS LYS A . n 
C 3 244 ALA 244 244 244 ALA ALA A . n 
C 3 245 TRP 245 245 245 TRP TRP A . n 
C 3 246 VAL 246 246 246 VAL VAL A . n 
C 3 247 PRO 247 247 247 PRO PRO A . n 
C 3 248 ARG 248 248 248 ARG ARG A . n 
C 3 249 PRO 249 249 249 PRO PRO A . n 
C 3 250 PRO 250 250 250 PRO PRO A . n 
C 3 251 ARG 251 251 251 ARG ARG A . n 
C 3 252 LEU 252 252 252 LEU LEU A . n 
C 3 253 CYS 253 253 253 CYS CYS A . n 
C 3 254 GLN 254 254 254 GLN GLN A . n 
C 3 255 TYR 255 255 255 TYR TYR A . n 
C 3 256 GLU 256 256 256 GLU GLU A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 GLN 258 258 258 GLN GLN A . n 
C 3 259 LYS 259 259 259 LYS LYS A . n 
C 3 260 ASN 260 260 260 ASN ASN A . n 
C 3 261 VAL 261 261 261 VAL VAL A . n 
C 3 262 ASN 262 262 262 ASN ASN A . n 
C 3 263 PHE 263 263 263 PHE PHE A . n 
C 3 264 SER 264 264 264 SER SER A . n 
C 3 265 PRO 265 265 265 PRO PRO A . n 
C 3 266 ILE 266 266 266 ILE ILE A . n 
C 3 267 GLY 267 267 267 GLY GLY A . n 
C 3 268 VAL 268 268 268 VAL VAL A . n 
C 3 269 THR 269 269 269 THR THR A . n 
C 3 270 THR 270 270 270 THR THR A . n 
C 3 271 SER 271 271 271 SER SER A . n 
C 3 272 ARG 272 272 272 ARG ARG A . n 
C 3 273 THR 273 273 273 THR THR A . n 
C 3 274 ASP 274 274 274 ASP ASP A . n 
C 3 275 ILE 275 275 275 ILE ILE A . n 
C 3 276 ILE 276 276 276 ILE ILE A . n 
C 3 277 THR 277 277 ?   ?   ?   A . n 
C 3 278 THR 278 278 ?   ?   ?   A . n 
D 4 1   SER 1   1   ?   ?   ?   B . n 
D 4 2   PRO 2   2   ?   ?   ?   B . n 
D 4 3   SER 3   3   ?   ?   ?   B . n 
D 4 4   ALA 4   4   ?   ?   ?   B . n 
D 4 5   GLU 5   5   ?   ?   ?   B . n 
D 4 6   GLU 6   6   ?   ?   ?   B . n 
D 4 7   CYS 7   7   ?   ?   ?   B . n 
D 4 8   GLY 8   8   ?   ?   ?   B . n 
D 4 9   TYR 9   9   ?   ?   ?   B . n 
D 4 10  SER 10  10  ?   ?   ?   B . n 
D 4 11  ASP 11  11  ?   ?   ?   B . n 
D 4 12  ARG 12  12  ?   ?   ?   B . n 
D 4 13  VAL 13  13  ?   ?   ?   B . n 
D 4 14  ARG 14  14  14  ARG ARG B . n 
D 4 15  SER 15  15  15  SER SER B . n 
D 4 16  ILE 16  16  16  ILE ILE B . n 
D 4 17  THR 17  17  17  THR THR B . n 
D 4 18  LEU 18  18  18  LEU LEU B . n 
D 4 19  GLY 19  19  19  GLY GLY B . n 
D 4 20  ASN 20  20  20  ASN ASN B . n 
D 4 21  SER 21  21  21  SER SER B . n 
D 4 22  THR 22  22  22  THR THR B . n 
D 4 23  ILE 23  23  23  ILE ILE B . n 
D 4 24  THR 24  24  24  THR THR B . n 
D 4 25  THR 25  25  25  THR THR B . n 
D 4 26  GLN 26  26  26  GLN GLN B . n 
D 4 27  GLU 27  27  ?   ?   ?   B . n 
D 4 28  CYS 28  28  ?   ?   ?   B . n 
D 4 29  ALA 29  29  ?   ?   ?   B . n 
D 4 30  ASN 30  30  30  ASN ASN B . n 
D 4 31  VAL 31  31  31  VAL VAL B . n 
D 4 32  VAL 32  32  32  VAL VAL B . n 
D 4 33  VAL 33  33  33  VAL VAL B . n 
D 4 34  GLY 34  34  34  GLY GLY B . n 
D 4 35  TYR 35  35  35  TYR TYR B . n 
D 4 36  GLY 36  36  36  GLY GLY B . n 
D 4 37  VAL 37  37  37  VAL VAL B . n 
D 4 38  TRP 38  38  38  TRP TRP B . n 
D 4 39  PRO 39  39  39  PRO PRO B . n 
D 4 40  GLU 40  40  40  GLU GLU B . n 
D 4 41  TYR 41  41  41  TYR TYR B . n 
D 4 42  LEU 42  42  42  LEU LEU B . n 
D 4 43  LYS 43  43  ?   ?   ?   B . n 
D 4 44  ASP 44  44  ?   ?   ?   B . n 
D 4 45  ASN 45  45  ?   ?   ?   B . n 
D 4 46  GLU 46  46  ?   ?   ?   B . n 
D 4 47  ALA 47  47  ?   ?   ?   B . n 
D 4 48  THR 48  48  ?   ?   ?   B . n 
D 4 49  ALA 49  49  ?   ?   ?   B . n 
D 4 50  GLU 50  50  ?   ?   ?   B . n 
D 4 51  ASP 51  51  51  ASP ASP B . n 
D 4 52  GLN 52  52  52  GLN GLN B . n 
D 4 53  PRO 53  53  53  PRO PRO B . n 
D 4 54  THR 54  54  54  THR THR B . n 
D 4 55  GLN 55  55  55  GLN GLN B . n 
D 4 56  PRO 56  56  56  PRO PRO B . n 
D 4 57  ASP 57  57  57  ASP ASP B . n 
D 4 58  VAL 58  58  58  VAL VAL B . n 
D 4 59  ALA 59  59  59  ALA ALA B . n 
D 4 60  THR 60  60  60  THR THR B . n 
D 4 61  CYS 61  61  61  CYS CYS B . n 
D 4 62  ARG 62  62  62  ARG ARG B . n 
D 4 63  PHE 63  63  63  PHE PHE B . n 
D 4 64  TYR 64  64  64  TYR TYR B . n 
D 4 65  THR 65  65  65  THR THR B . n 
D 4 66  LEU 66  66  66  LEU LEU B . n 
D 4 67  GLU 67  67  67  GLU GLU B . n 
D 4 68  SER 68  68  68  SER SER B . n 
D 4 69  VAL 69  69  69  VAL VAL B . n 
D 4 70  GLN 70  70  70  GLN GLN B . n 
D 4 71  TRP 71  71  71  TRP TRP B . n 
D 4 72  MET 72  72  72  MET MET B . n 
D 4 73  LYS 73  73  73  LYS LYS B . n 
D 4 74  ASN 74  74  74  ASN ASN B . n 
D 4 75  SER 75  75  75  SER SER B . n 
D 4 76  ALA 76  76  76  ALA ALA B . n 
D 4 77  GLY 77  77  77  GLY GLY B . n 
D 4 78  TRP 78  78  78  TRP TRP B . n 
D 4 79  TRP 79  79  79  TRP TRP B . n 
D 4 80  TRP 80  80  80  TRP TRP B . n 
D 4 81  LYS 81  81  81  LYS LYS B . n 
D 4 82  LEU 82  82  82  LEU LEU B . n 
D 4 83  PRO 83  83  83  PRO PRO B . n 
D 4 84  ASP 84  84  84  ASP ASP B . n 
D 4 85  ALA 85  85  85  ALA ALA B . n 
D 4 86  LEU 86  86  86  LEU LEU B . n 
D 4 87  SER 87  87  87  SER SER B . n 
D 4 88  GLN 88  88  88  GLN GLN B . n 
D 4 89  MET 89  89  89  MET MET B . n 
D 4 90  GLY 90  90  90  GLY GLY B . n 
D 4 91  LEU 91  91  91  LEU LEU B . n 
D 4 92  PHE 92  92  92  PHE PHE B . n 
D 4 93  GLY 93  93  93  GLY GLY B . n 
D 4 94  GLN 94  94  94  GLN GLN B . n 
D 4 95  ASN 95  95  95  ASN ASN B . n 
D 4 96  MET 96  96  96  MET MET B . n 
D 4 97  GLN 97  97  97  GLN GLN B . n 
D 4 98  TYR 98  98  98  TYR TYR B . n 
D 4 99  HIS 99  99  99  HIS HIS B . n 
D 4 100 TYR 100 100 100 TYR TYR B . n 
D 4 101 LEU 101 101 101 LEU LEU B . n 
D 4 102 GLY 102 102 102 GLY GLY B . n 
D 4 103 ARG 103 103 103 ARG ARG B . n 
D 4 104 THR 104 104 104 THR THR B . n 
D 4 105 GLY 105 105 105 GLY GLY B . n 
D 4 106 TYR 106 106 106 TYR TYR B . n 
D 4 107 THR 107 107 107 THR THR B . n 
D 4 108 ILE 108 108 108 ILE ILE B . n 
D 4 109 HIS 109 109 109 HIS HIS B . n 
D 4 110 VAL 110 110 110 VAL VAL B . n 
D 4 111 GLN 111 111 111 GLN GLN B . n 
D 4 112 CYS 112 112 112 CYS CYS B . n 
D 4 113 ASN 113 113 113 ASN ASN B . n 
D 4 114 ALA 114 114 114 ALA ALA B . n 
D 4 115 SER 115 115 115 SER SER B . n 
D 4 116 LYS 116 116 116 LYS LYS B . n 
D 4 117 PHE 117 117 117 PHE PHE B . n 
D 4 118 HIS 118 118 118 HIS HIS B . n 
D 4 119 GLN 119 119 119 GLN GLN B . n 
D 4 120 GLY 120 120 120 GLY GLY B . n 
D 4 121 CYS 121 121 121 CYS CYS B . n 
D 4 122 LEU 122 122 122 LEU LEU B . n 
D 4 123 LEU 123 123 123 LEU LEU B . n 
D 4 124 VAL 124 124 124 VAL VAL B . n 
D 4 125 VAL 125 125 125 VAL VAL B . n 
D 4 126 CYS 126 126 126 CYS CYS B . n 
D 4 127 VAL 127 127 127 VAL VAL B . n 
D 4 128 PRO 128 128 128 PRO PRO B . n 
D 4 129 GLU 129 129 129 GLU GLU B . n 
D 4 130 ALA 130 130 130 ALA ALA B . n 
D 4 131 GLU 131 131 131 GLU GLU B . n 
D 4 132 MET 132 132 132 MET MET B . n 
D 4 133 GLY 133 133 133 GLY GLY B . n 
D 4 134 CYS 134 134 134 CYS CYS B . n 
D 4 135 SER 135 135 135 SER SER B . n 
D 4 136 ASN 136 136 136 ASN ASN B . n 
D 4 137 LEU 137 137 137 LEU LEU B . n 
D 4 138 ASN 138 138 138 ASN ASN B . n 
D 4 139 ASN 139 139 139 ASN ASN B . n 
D 4 140 THR 140 140 140 THR THR B . n 
D 4 141 PRO 141 141 141 PRO PRO B . n 
D 4 142 GLU 142 142 142 GLU GLU B . n 
D 4 143 PHE 143 143 143 PHE PHE B . n 
D 4 144 SER 144 144 144 SER SER B . n 
D 4 145 GLU 145 145 145 GLU GLU B . n 
D 4 146 LEU 146 146 146 LEU LEU B . n 
D 4 147 SER 147 147 147 SER SER B . n 
D 4 148 GLY 148 148 148 GLY GLY B . n 
D 4 149 GLY 149 149 149 GLY GLY B . n 
D 4 150 ASP 150 150 150 ASP ASP B . n 
D 4 151 SER 151 151 151 SER SER B . n 
D 4 152 ALA 152 152 152 ALA ALA B . n 
D 4 153 ARG 153 153 153 ARG ARG B . n 
D 4 154 MET 154 154 154 MET MET B . n 
D 4 155 PHE 155 155 155 PHE PHE B . n 
D 4 156 THR 156 156 156 THR THR B . n 
D 4 157 ASP 157 157 157 ASP ASP B . n 
D 4 158 THR 158 158 158 THR THR B . n 
D 4 159 GLN 159 159 159 GLN GLN B . n 
D 4 160 VAL 160 160 160 VAL VAL B . n 
D 4 161 GLY 161 161 161 GLY GLY B . n 
D 4 162 GLU 162 162 162 GLU GLU B . n 
D 4 163 SER 163 163 163 SER SER B . n 
D 4 164 ASN 164 164 164 ASN ASN B . n 
D 4 165 ALA 165 165 165 ALA ALA B . n 
D 4 166 LYS 166 166 166 LYS LYS B . n 
D 4 167 LYS 167 167 167 LYS LYS B . n 
D 4 168 VAL 168 168 168 VAL VAL B . n 
D 4 169 GLN 169 169 169 GLN GLN B . n 
D 4 170 THR 170 170 170 THR THR B . n 
D 4 171 ALA 171 171 171 ALA ALA B . n 
D 4 172 VAL 172 172 172 VAL VAL B . n 
D 4 173 TRP 173 173 173 TRP TRP B . n 
D 4 174 ASN 174 174 174 ASN ASN B . n 
D 4 175 ALA 175 175 175 ALA ALA B . n 
D 4 176 GLY 176 176 176 GLY GLY B . n 
D 4 177 MET 177 177 177 MET MET B . n 
D 4 178 GLY 178 178 178 GLY GLY B . n 
D 4 179 VAL 179 179 179 VAL VAL B . n 
D 4 180 GLY 180 180 180 GLY GLY B . n 
D 4 181 VAL 181 181 181 VAL VAL B . n 
D 4 182 GLY 182 182 182 GLY GLY B . n 
D 4 183 ASN 183 183 183 ASN ASN B . n 
D 4 184 LEU 184 184 184 LEU LEU B . n 
D 4 185 THR 185 185 185 THR THR B . n 
D 4 186 ILE 186 186 186 ILE ILE B . n 
D 4 187 PHE 187 187 187 PHE PHE B . n 
D 4 188 PRO 188 188 188 PRO PRO B . n 
D 4 189 HIS 189 189 189 HIS HIS B . n 
D 4 190 GLN 190 190 190 GLN GLN B . n 
D 4 191 TRP 191 191 191 TRP TRP B . n 
D 4 192 ILE 192 192 192 ILE ILE B . n 
D 4 193 ASN 193 193 193 ASN ASN B . n 
D 4 194 LEU 194 194 194 LEU LEU B . n 
D 4 195 ARG 195 195 195 ARG ARG B . n 
D 4 196 THR 196 196 196 THR THR B . n 
D 4 197 ASN 197 197 197 ASN ASN B . n 
D 4 198 ASN 198 198 198 ASN ASN B . n 
D 4 199 SER 199 199 199 SER SER B . n 
D 4 200 ALA 200 200 200 ALA ALA B . n 
D 4 201 THR 201 201 201 THR THR B . n 
D 4 202 LEU 202 202 202 LEU LEU B . n 
D 4 203 VAL 203 203 203 VAL VAL B . n 
D 4 204 MET 204 204 204 MET MET B . n 
D 4 205 PRO 205 205 205 PRO PRO B . n 
D 4 206 TYR 206 206 206 TYR TYR B . n 
D 4 207 ILE 207 207 207 ILE ILE B . n 
D 4 208 ASN 208 208 208 ASN ASN B . n 
D 4 209 SER 209 209 209 SER SER B . n 
D 4 210 VAL 210 210 210 VAL VAL B . n 
D 4 211 PRO 211 211 211 PRO PRO B . n 
D 4 212 MET 212 212 212 MET MET B . n 
D 4 213 ASP 213 213 213 ASP ASP B . n 
D 4 214 ASN 214 214 214 ASN ASN B . n 
D 4 215 MET 215 215 215 MET MET B . n 
D 4 216 PHE 216 216 216 PHE PHE B . n 
D 4 217 ARG 217 217 217 ARG ARG B . n 
D 4 218 HIS 218 218 218 HIS HIS B . n 
D 4 219 ASN 219 219 219 ASN ASN B . n 
D 4 220 ASN 220 220 220 ASN ASN B . n 
D 4 221 LEU 221 221 221 LEU LEU B . n 
D 4 222 THR 222 222 222 THR THR B . n 
D 4 223 LEU 223 223 223 LEU LEU B . n 
D 4 224 MET 224 224 224 MET MET B . n 
D 4 225 ILE 225 225 225 ILE ILE B . n 
D 4 226 ILE 226 226 226 ILE ILE B . n 
D 4 227 PRO 227 227 227 PRO PRO B . n 
D 4 228 PHE 228 228 228 PHE PHE B . n 
D 4 229 VAL 229 229 229 VAL VAL B . n 
D 4 230 PRO 230 230 230 PRO PRO B . n 
D 4 231 LEU 231 231 231 LEU LEU B . n 
D 4 232 ASN 232 232 232 ASN ASN B . n 
D 4 233 TYR 233 233 233 TYR TYR B . n 
D 4 234 SER 234 234 234 SER SER B . n 
D 4 235 GLU 235 235 235 GLU GLU B . n 
D 4 236 GLY 236 236 236 GLY GLY B . n 
D 4 237 SER 237 237 237 SER SER B . n 
D 4 238 SER 238 238 238 SER SER B . n 
D 4 239 PRO 239 239 239 PRO PRO B . n 
D 4 240 TYR 240 240 240 TYR TYR B . n 
D 4 241 VAL 241 241 241 VAL VAL B . n 
D 4 242 PRO 242 242 242 PRO PRO B . n 
D 4 243 ILE 243 243 243 ILE ILE B . n 
D 4 244 THR 244 244 244 THR THR B . n 
D 4 245 VAL 245 245 245 VAL VAL B . n 
D 4 246 THR 246 246 246 THR THR B . n 
D 4 247 ILE 247 247 247 ILE ILE B . n 
D 4 248 ALA 248 248 248 ALA ALA B . n 
D 4 249 PRO 249 249 249 PRO PRO B . n 
D 4 250 MET 250 250 250 MET MET B . n 
D 4 251 CYS 251 251 251 CYS CYS B . n 
D 4 252 ALA 252 252 252 ALA ALA B . n 
D 4 253 GLU 253 253 253 GLU GLU B . n 
D 4 254 TYR 254 254 254 TYR TYR B . n 
D 4 255 ASN 255 255 255 ASN ASN B . n 
D 4 256 GLY 256 256 256 GLY GLY B . n 
D 4 257 LEU 257 257 257 LEU LEU B . n 
D 4 258 ARG 258 258 ?   ?   ?   B . n 
D 4 259 LEU 259 259 ?   ?   ?   B . n 
D 4 260 ALA 260 260 ?   ?   ?   B . n 
D 4 261 SER 261 261 ?   ?   ?   B . n 
D 4 262 ASN 262 262 ?   ?   ?   B . n 
D 4 263 GLN 263 263 ?   ?   ?   B . n 
E 5 1   GLY 1   1   1   GLY GLY C . n 
E 5 2   LEU 2   2   2   LEU LEU C . n 
E 5 3   PRO 3   3   3   PRO PRO C . n 
E 5 4   VAL 4   4   4   VAL VAL C . n 
E 5 5   MET 5   5   5   MET MET C . n 
E 5 6   THR 6   6   6   THR THR C . n 
E 5 7   THR 7   7   7   THR THR C . n 
E 5 8   PRO 8   8   8   PRO PRO C . n 
E 5 9   GLY 9   9   9   GLY GLY C . n 
E 5 10  SER 10  10  10  SER SER C . n 
E 5 11  THR 11  11  11  THR THR C . n 
E 5 12  GLN 12  12  12  GLN GLN C . n 
E 5 13  PHE 13  13  13  PHE PHE C . n 
E 5 14  LEU 14  14  14  LEU LEU C . n 
E 5 15  THR 15  15  15  THR THR C . n 
E 5 16  SER 16  16  16  SER SER C . n 
E 5 17  ASP 17  17  17  ASP ASP C . n 
E 5 18  ASP 18  18  18  ASP ASP C . n 
E 5 19  PHE 19  19  19  PHE PHE C . n 
E 5 20  GLN 20  20  20  GLN GLN C . n 
E 5 21  SER 21  21  21  SER SER C . n 
E 5 22  PRO 22  22  22  PRO PRO C . n 
E 5 23  SER 23  23  23  SER SER C . n 
E 5 24  ALA 24  24  24  ALA ALA C . n 
E 5 25  MET 25  25  25  MET MET C . n 
E 5 26  PRO 26  26  26  PRO PRO C . n 
E 5 27  GLN 27  27  27  GLN GLN C . n 
E 5 28  PHE 28  28  28  PHE PHE C . n 
E 5 29  ASP 29  29  29  ASP ASP C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  THR 31  31  31  THR THR C . n 
E 5 32  PRO 32  32  32  PRO PRO C . n 
E 5 33  GLU 33  33  33  GLU GLU C . n 
E 5 34  MET 34  34  34  MET MET C . n 
E 5 35  GLN 35  35  35  GLN GLN C . n 
E 5 36  ILE 36  36  36  ILE ILE C . n 
E 5 37  PRO 37  37  37  PRO PRO C . n 
E 5 38  GLY 38  38  38  GLY GLY C . n 
E 5 39  ARG 39  39  39  ARG ARG C . n 
E 5 40  VAL 40  40  40  VAL VAL C . n 
E 5 41  ASN 41  41  41  ASN ASN C . n 
E 5 42  ASN 42  42  42  ASN ASN C . n 
E 5 43  LEU 43  43  43  LEU LEU C . n 
E 5 44  MET 44  44  44  MET MET C . n 
E 5 45  GLU 45  45  45  GLU GLU C . n 
E 5 46  ILE 46  46  46  ILE ILE C . n 
E 5 47  ALA 47  47  47  ALA ALA C . n 
E 5 48  GLU 48  48  48  GLU GLU C . n 
E 5 49  VAL 49  49  49  VAL VAL C . n 
E 5 50  ASP 50  50  50  ASP ASP C . n 
E 5 51  SER 51  51  51  SER SER C . n 
E 5 52  VAL 52  52  52  VAL VAL C . n 
E 5 53  VAL 53  53  53  VAL VAL C . n 
E 5 54  PRO 54  54  54  PRO PRO C . n 
E 5 55  VAL 55  55  55  VAL VAL C . n 
E 5 56  ASN 56  56  56  ASN ASN C . n 
E 5 57  ASN 57  57  57  ASN ASN C . n 
E 5 58  THR 58  58  58  THR THR C . n 
E 5 59  GLU 59  59  59  GLU GLU C . n 
E 5 60  ASP 60  60  60  ASP ASP C . n 
E 5 61  ASN 61  61  61  ASN ASN C . n 
E 5 62  VAL 62  62  62  VAL VAL C . n 
E 5 63  SER 63  63  63  SER SER C . n 
E 5 64  SER 64  64  64  SER SER C . n 
E 5 65  LEU 65  65  65  LEU LEU C . n 
E 5 66  LYS 66  66  66  LYS LYS C . n 
E 5 67  ALA 67  67  67  ALA ALA C . n 
E 5 68  TYR 68  68  68  TYR TYR C . n 
E 5 69  GLN 69  69  69  GLN GLN C . n 
E 5 70  ILE 70  70  70  ILE ILE C . n 
E 5 71  PRO 71  71  71  PRO PRO C . n 
E 5 72  VAL 72  72  72  VAL VAL C . n 
E 5 73  GLN 73  73  73  GLN GLN C . n 
E 5 74  SER 74  74  74  SER SER C . n 
E 5 75  ASN 75  75  75  ASN ASN C . n 
E 5 76  SER 76  76  76  SER SER C . n 
E 5 77  ASP 77  77  77  ASP ASP C . n 
E 5 78  ASN 78  78  78  ASN ASN C . n 
E 5 79  GLY 79  79  79  GLY GLY C . n 
E 5 80  LYS 80  80  80  LYS LYS C . n 
E 5 81  GLN 81  81  81  GLN GLN C . n 
E 5 82  VAL 82  82  82  VAL VAL C . n 
E 5 83  PHE 83  83  83  PHE PHE C . n 
E 5 84  GLY 84  84  84  GLY GLY C . n 
E 5 85  PHE 85  85  85  PHE PHE C . n 
E 5 86  PRO 86  86  86  PRO PRO C . n 
E 5 87  LEU 87  87  87  LEU LEU C . n 
E 5 88  GLN 88  88  88  GLN GLN C . n 
E 5 89  PRO 89  89  89  PRO PRO C . n 
E 5 90  GLY 90  90  90  GLY GLY C . n 
E 5 91  ALA 91  91  91  ALA ALA C . n 
E 5 92  ASN 92  92  92  ASN ASN C . n 
E 5 93  ASN 93  93  93  ASN ASN C . n 
E 5 94  VAL 94  94  94  VAL VAL C . n 
E 5 95  LEU 95  95  95  LEU LEU C . n 
E 5 96  ASN 96  96  96  ASN ASN C . n 
E 5 97  ARG 97  97  97  ARG ARG C . n 
E 5 98  THR 98  98  98  THR THR C . n 
E 5 99  LEU 99  99  99  LEU LEU C . n 
E 5 100 LEU 100 100 100 LEU LEU C . n 
E 5 101 GLY 101 101 101 GLY GLY C . n 
E 5 102 GLU 102 102 102 GLU GLU C . n 
E 5 103 ILE 103 103 103 ILE ILE C . n 
E 5 104 LEU 104 104 104 LEU LEU C . n 
E 5 105 ASN 105 105 105 ASN ASN C . n 
E 5 106 TYR 106 106 106 TYR TYR C . n 
E 5 107 TYR 107 107 107 TYR TYR C . n 
E 5 108 THR 108 108 108 THR THR C . n 
E 5 109 HIS 109 109 109 HIS HIS C . n 
E 5 110 TRP 110 110 110 TRP TRP C . n 
E 5 111 SER 111 111 111 SER SER C . n 
E 5 112 GLY 112 112 112 GLY GLY C . n 
E 5 113 SER 113 113 113 SER SER C . n 
E 5 114 ILE 114 114 114 ILE ILE C . n 
E 5 115 LYS 115 115 115 LYS LYS C . n 
E 5 116 LEU 116 116 116 LEU LEU C . n 
E 5 117 THR 117 117 117 THR THR C . n 
E 5 118 PHE 118 118 118 PHE PHE C . n 
E 5 119 MET 119 119 119 MET MET C . n 
E 5 120 PHE 120 120 120 PHE PHE C . n 
E 5 121 CYS 121 121 121 CYS CYS C . n 
E 5 122 GLY 122 122 122 GLY GLY C . n 
E 5 123 SER 123 123 123 SER SER C . n 
E 5 124 ALA 124 124 124 ALA ALA C . n 
E 5 125 MET 125 125 125 MET MET C . n 
E 5 126 ALA 126 126 126 ALA ALA C . n 
E 5 127 THR 127 127 127 THR THR C . n 
E 5 128 GLY 128 128 128 GLY GLY C . n 
E 5 129 LYS 129 129 129 LYS LYS C . n 
E 5 130 PHE 130 130 130 PHE PHE C . n 
E 5 131 LEU 131 131 131 LEU LEU C . n 
E 5 132 LEU 132 132 132 LEU LEU C . n 
E 5 133 ALA 133 133 133 ALA ALA C . n 
E 5 134 TYR 134 134 134 TYR TYR C . n 
E 5 135 SER 135 135 135 SER SER C . n 
E 5 136 PRO 136 136 136 PRO PRO C . n 
E 5 137 PRO 137 137 137 PRO PRO C . n 
E 5 138 GLY 138 138 138 GLY GLY C . n 
E 5 139 ALA 139 139 139 ALA ALA C . n 
E 5 140 GLY 140 140 140 GLY GLY C . n 
E 5 141 VAL 141 141 141 VAL VAL C . n 
E 5 142 PRO 142 142 142 PRO PRO C . n 
E 5 143 LYS 143 143 143 LYS LYS C . n 
E 5 144 ASN 144 144 144 ASN ASN C . n 
E 5 145 ARG 145 145 145 ARG ARG C . n 
E 5 146 LYS 146 146 146 LYS LYS C . n 
E 5 147 ASP 147 147 147 ASP ASP C . n 
E 5 148 ALA 148 148 148 ALA ALA C . n 
E 5 149 MET 149 149 149 MET MET C . n 
E 5 150 LEU 150 150 150 LEU LEU C . n 
E 5 151 GLY 151 151 151 GLY GLY C . n 
E 5 152 THR 152 152 152 THR THR C . n 
E 5 153 HIS 153 153 153 HIS HIS C . n 
E 5 154 VAL 154 154 154 VAL VAL C . n 
E 5 155 ILE 155 155 155 ILE ILE C . n 
E 5 156 TRP 156 156 156 TRP TRP C . n 
E 5 157 ASP 157 157 157 ASP ASP C . n 
E 5 158 VAL 158 158 158 VAL VAL C . n 
E 5 159 GLY 159 159 159 GLY GLY C . n 
E 5 160 LEU 160 160 160 LEU LEU C . n 
E 5 161 GLN 161 161 161 GLN GLN C . n 
E 5 162 SER 162 162 162 SER SER C . n 
E 5 163 SER 163 163 163 SER SER C . n 
E 5 164 CYS 164 164 164 CYS CYS C . n 
E 5 165 VAL 165 165 165 VAL VAL C . n 
E 5 166 LEU 166 166 166 LEU LEU C . n 
E 5 167 CYS 167 167 167 CYS CYS C . n 
E 5 168 VAL 168 168 168 VAL VAL C . n 
E 5 169 PRO 169 169 169 PRO PRO C . n 
E 5 170 TRP 170 170 170 TRP TRP C . n 
E 5 171 ILE 171 171 171 ILE ILE C . n 
E 5 172 SER 172 172 172 SER SER C . n 
E 5 173 GLN 173 173 ?   ?   ?   C . n 
E 5 174 THR 174 174 ?   ?   ?   C . n 
E 5 175 HIS 175 175 ?   ?   ?   C . n 
E 5 176 TYR 176 176 ?   ?   ?   C . n 
E 5 177 ARG 177 177 ?   ?   ?   C . n 
E 5 178 TYR 178 178 ?   ?   ?   C . n 
E 5 179 VAL 179 179 ?   ?   ?   C . n 
E 5 180 VAL 180 180 ?   ?   ?   C . n 
E 5 181 GLU 181 181 ?   ?   ?   C . n 
E 5 182 ASP 182 182 ?   ?   ?   C . n 
E 5 183 GLU 183 183 ?   ?   ?   C . n 
E 5 184 TYR 184 184 ?   ?   ?   C . n 
E 5 185 THR 185 185 ?   ?   ?   C . n 
E 5 186 ALA 186 186 186 ALA ALA C . n 
E 5 187 ALA 187 187 187 ALA ALA C . n 
E 5 188 GLY 188 188 188 GLY GLY C . n 
E 5 189 TYR 189 189 189 TYR TYR C . n 
E 5 190 VAL 190 190 190 VAL VAL C . n 
E 5 191 THR 191 191 191 THR THR C . n 
E 5 192 CYS 192 192 192 CYS CYS C . n 
E 5 193 TRP 193 193 193 TRP TRP C . n 
E 5 194 TYR 194 194 194 TYR TYR C . n 
E 5 195 GLN 195 195 195 GLN GLN C . n 
E 5 196 THR 196 196 196 THR THR C . n 
E 5 197 ASN 197 197 197 ASN ASN C . n 
E 5 198 ILE 198 198 198 ILE ILE C . n 
E 5 199 VAL 199 199 199 VAL VAL C . n 
E 5 200 VAL 200 200 200 VAL VAL C . n 
E 5 201 PRO 201 201 201 PRO PRO C . n 
E 5 202 ALA 202 202 202 ALA ALA C . n 
E 5 203 ASP 203 203 203 ASP ASP C . n 
E 5 204 VAL 204 204 204 VAL VAL C . n 
E 5 205 GLN 205 205 205 GLN GLN C . n 
E 5 206 SER 206 206 206 SER SER C . n 
E 5 207 SER 207 207 207 SER SER C . n 
E 5 208 CYS 208 208 208 CYS CYS C . n 
E 5 209 ASP 209 209 209 ASP ASP C . n 
E 5 210 ILE 210 210 210 ILE ILE C . n 
E 5 211 LEU 211 211 211 LEU LEU C . n 
E 5 212 CYS 212 212 212 CYS CYS C . n 
E 5 213 PHE 213 213 213 PHE PHE C . n 
E 5 214 VAL 214 214 214 VAL VAL C . n 
E 5 215 SER 215 215 215 SER SER C . n 
E 5 216 ALA 216 216 216 ALA ALA C . n 
E 5 217 CYS 217 217 217 CYS CYS C . n 
E 5 218 ASN 218 218 218 ASN ASN C . n 
E 5 219 ASP 219 219 219 ASP ASP C . n 
E 5 220 PHE 220 220 220 PHE PHE C . n 
E 5 221 SER 221 221 221 SER SER C . n 
E 5 222 VAL 222 222 222 VAL VAL C . n 
E 5 223 ARG 223 223 223 ARG ARG C . n 
E 5 224 MET 224 224 224 MET MET C . n 
E 5 225 LEU 225 225 225 LEU LEU C . n 
E 5 226 LYS 226 226 226 LYS LYS C . n 
E 5 227 ASP 227 227 227 ASP ASP C . n 
E 5 228 THR 228 228 228 THR THR C . n 
E 5 229 PRO 229 229 229 PRO PRO C . n 
E 5 230 PHE 230 230 230 PHE PHE C . n 
E 5 231 ILE 231 231 231 ILE ILE C . n 
E 5 232 ARG 232 232 232 ARG ARG C . n 
E 5 233 GLN 233 233 ?   ?   ?   C . n 
E 5 234 ASP 234 234 ?   ?   ?   C . n 
E 5 235 THR 235 235 ?   ?   ?   C . n 
E 5 236 PHE 236 236 ?   ?   ?   C . n 
E 5 237 TYR 237 237 ?   ?   ?   C . n 
E 5 238 GLN 238 238 ?   ?   ?   C . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              abing0811@xmu.edu.cn 
_pdbx_contact_author.name_first         Qingbing 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7516-9965 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     -0.80901699 -0.30901699 0.50000000  193.81546  0.50000000  -0.80901699 0.30901699  
0.00000    0.30901699  0.50000000  0.80901699  -507.41547 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  313.60001  0.80901700  0.30901699  -0.50000000 
119.78455  0.30901699  0.50000000  0.80901700  -193.81546 
3  'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901700  313.60000  0.50000000  -0.80901700 -0.30901700 
507.41547  0.80901699  0.30901700  0.50000000  -193.81546 
4  'point symmetry operation' ?     ?     -0.30901700 0.50000000  0.80901700  0.00000    -0.50000000 -0.80901699 0.30901700  
627.20001  0.80901700  -0.30901699 0.50000000  0.00000    
5  'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901700  -193.81546 -0.80901699 0.30901700  0.50000000  
313.60000  0.30901700  -0.50000000 0.80901699  119.78454  
6  'point symmetry operation' ?     ?     -0.80901699 0.30901700  0.50000001  313.60000  0.30901699  -0.50000000 0.80901699  
119.78454  0.49999999  0.80901700  0.30901699  -193.81546 
7  'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
8  'point symmetry operation' ?     ?     0.80901700  0.30901699  -0.50000000 119.78455  0.30901699  0.50000000  0.80901699  
-193.81547 0.50000000  -0.80901700 0.30901699  313.60001  
9  'point symmetry operation' ?     ?     0.50000000  -0.80901700 -0.30901699 507.41547  0.80901699  0.30901699  0.50000000  
-193.81546 -0.30901700 -0.50000000 0.80901699  313.60001  
10 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901700  627.20001  0.80901699  -0.30901700 0.50000000  
0.00000    -0.30901700 0.50000000  0.80901699  0.00000    
11 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  627.20001  -0.80901700 0.30901699  -0.49999999 
627.20002  0.30901700  -0.50000001 -0.80901699 627.20002  
12 'point symmetry operation' ?     ?     -0.80901700 0.30901700  0.50000000  313.60001  -0.30901700 0.50000000  -0.80901699 
507.41547  -0.50000000 -0.80901700 -0.30901699 821.01548  
13 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
627.20002  -1.00000000 0.00000000  0.00000000  627.20001  
14 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 119.78455  -0.30901699 -0.50000000 -0.80901700 
821.01548  -0.50000000 0.80901700  -0.30901699 313.60001  
15 'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901700 507.41547  -0.80901699 -0.30901700 -0.50000000 
821.01548  0.30901700  0.50000000  -0.80901699 313.60001  
16 'point symmetry operation' ?     ?     0.30901699  0.49999999  -0.80901700 313.60001  0.50000001  -0.80901699 -0.30901700 
507.41547  -0.80901699 -0.30901699 -0.50000000 821.01548  
17 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901700 627.20002  -0.50000000 -0.80901699 0.30901699  
627.20001  -0.80901699 0.30901700  -0.50000000 627.20002  
18 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901700 821.01548  -0.80901700 0.30901699  0.50000000  
313.60001  -0.30901699 0.50000000  -0.80901699 507.41548  
19 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  627.20001  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 627.20002  
20 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901700 313.60001  0.80901699  0.30901700  -0.50000000 
119.78455  -0.30901700 -0.50000000 -0.80901699 821.01548  
21 'point symmetry operation' ?     ?     -0.49999999 -0.80901700 -0.30901699 821.01548  0.80901699  -0.30901700 -0.50000001 
313.60001  0.30901699  -0.50000000 0.80901699  119.78454  
22 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  627.20001  0.00000000  -1.00000000 0.00000000  
627.20002  0.00000000  0.00000000  1.00000000  0.00000    
23 'point symmetry operation' ?     ?     -0.50000000 0.80901700  -0.30901699 313.60001  -0.80901700 -0.30901699 0.50000000  
507.41547  0.30901699  0.50000000  0.80901699  -193.81546 
24 'point symmetry operation' ?     ?     0.30901700  0.50000000  -0.80901699 313.60001  -0.50000000 0.80901700  0.30901699  
119.78454  0.80901699  0.30901699  0.50000000  -193.81546 
25 'point symmetry operation' ?     ?     0.30901700  -0.50000000 -0.80901699 627.20002  0.50000000  0.80901699  -0.30901700 
0.00000    0.80901699  -0.30901700 0.50000000  0.00000    
26 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 627.20002  -1.00000000 0.00000000  0.00000000  
627.20002  0.00000000  1.00000000  0.00000000  0.00000    
27 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901700 821.01548  -0.50000000 0.80901699  -0.30901699 
313.60001  0.80901700  0.30901699  -0.50000000 119.78455  
28 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 -0.50000000 821.01548  0.30901699  0.50000000  -0.80901700 
313.60001  0.50000000  -0.80901700 -0.30901700 507.41548  
29 'point symmetry operation' ?     ?     -0.80901700 0.30901699  -0.50000000 627.20002  0.30901700  -0.50000000 -0.80901700 
627.20002  -0.50000000 -0.80901699 0.30901700  627.20001  
30 'point symmetry operation' ?     ?     -0.30901700 0.50000000  -0.80901699 507.41547  -0.50000000 -0.80901699 -0.30901700 
821.01548  -0.80901699 0.30901700  0.50000000  313.60001  
31 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  -193.81546 -0.30901699 -0.49999999 0.80901700  
313.60000  0.50000001  -0.80901699 -0.30901700 507.41547  
32 'point symmetry operation' ?     ?     0.80901699  -0.30901700 0.50000000  0.00000    -0.30901699 0.50000000  0.80901700  
0.00000    -0.50000000 -0.80901699 0.30901699  627.20002  
33 'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  119.78454  0.50000000  0.80901699  0.30901700  
-193.81546 -0.80901700 0.30901699  0.50000000  313.60001  
34 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
35 'point symmetry operation' ?     ?     0.30901700  0.50000000  0.80901699  -193.81547 0.50000000  -0.80901699 0.30901700  
313.60001  0.80901699  0.30901700  -0.50000000 119.78455  
36 'point symmetry operation' ?     ?     -0.30901700 0.50000001  0.80901699  0.00000    0.50000000  0.80901699  -0.30901699 
0.00000    -0.80901700 0.30901699  -0.49999999 627.20002  
37 'point symmetry operation' ?     ?     0.50000000  0.80901700  0.30901699  -193.81546 0.80901700  -0.30901700 -0.50000000 
313.60001  -0.30901700 0.50000000  -0.80901699 507.41547  
38 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
627.20001  0.00000000  0.00000000  -1.00000000 627.20002  
39 'point symmetry operation' ?     ?     0.50000000  -0.80901700 0.30901699  313.60001  -0.80901699 -0.30901699 0.50000000  
507.41547  -0.30901699 -0.50000000 -0.80901700 821.01548  
40 'point symmetry operation' ?     ?     -0.30901700 -0.50000000 0.80901699  313.60001  -0.50000000 0.80901699  0.30901700  
119.78454  -0.80901699 -0.30901700 -0.50000000 821.01548  
41 'point symmetry operation' ?     ?     -0.50000001 0.80901699  0.30901700  119.78454  -0.80901699 -0.30901699 -0.50000000 
821.01548  -0.30901699 -0.49999999 0.80901700  313.60000  
42 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000    -0.80901699 0.30901700  -0.50000000 
627.20001  -0.30901699 0.50000000  0.80901700  0.00000    
43 'point symmetry operation' ?     ?     0.80901700  -0.30901699 -0.50000000 313.60001  -0.30901699 0.50000000  -0.80901699 
507.41547  0.50000000  0.80901699  0.30901700  -193.81546 
44 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  627.20001  0.00000000  0.00000000  -1.00000000 
627.20002  1.00000000  0.00000000  0.00000000  0.00000    
45 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 0.50000000  507.41547  -0.30901700 -0.50000000 -0.80901699 
821.01548  0.50000000  -0.80901699 0.30901700  313.60001  
46 'point symmetry operation' ?     ?     0.80901700  -0.30901699 0.49999999  0.00000    0.30901700  -0.50000001 -0.80901699 
627.20002  0.50000000  0.80901699  -0.30901699 0.00000    
47 'point symmetry operation' ?     ?     0.30901700  -0.50000000 0.80901699  119.78454  -0.50000000 -0.80901700 -0.30901699 
821.01548  0.80901700  -0.30901700 -0.50000000 313.60001  
48 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
627.20001  0.00000000  -1.00000000 0.00000000  627.20002  
49 'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901700  -193.81546 -0.50000000 0.80901700  -0.30901699 
313.60001  -0.80901699 -0.30901699 0.50000000  507.41547  
50 'point symmetry operation' ?     ?     0.80901699  0.30901700  0.50000000  -193.81546 0.30901700  0.50000000  -0.80901699 
313.60001  -0.50000000 0.80901699  0.30901700  119.78454  
51 'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 507.41547  0.49999999  0.80901700  0.30901699  
-193.81546 0.80901699  -0.30901700 -0.50000001 313.60001  
52 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 627.20002  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  627.20002  
53 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 821.01548  0.50000000  -0.80901700 0.30901699  
313.60001  -0.80901700 -0.30901699 0.50000000  507.41547  
54 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 821.01548  -0.30901700 -0.50000000 0.80901699  
313.60001  -0.50000000 0.80901700  0.30901699  119.78454  
55 'point symmetry operation' ?     ?     -0.80901699 0.30901700  -0.50000000 627.20001  -0.30901700 0.50000000  0.80901699  
0.00000    0.50000000  0.80901699  -0.30901700 0.00000    
56 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  627.20002  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  627.20002  
57 'point symmetry operation' ?     ?     -0.80901700 -0.30901699 0.50000000  507.41547  0.30901699  0.50000000  0.80901700  
-193.81546 -0.50000000 0.80901699  -0.30901699 313.60001  
58 'point symmetry operation' ?     ?     -0.50000000 0.80901700  0.30901700  119.78454  0.80901699  0.30901700  0.50000000  
-193.81546 0.30901699  0.50000000  -0.80901700 313.60001  
59 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901700 0.00000    0.80901700  -0.30901699 0.50000000  
0.00000    0.30901700  -0.50000000 -0.80901700 627.20002  
60 'point symmetry operation' ?     ?     0.80901699  -0.30901700 -0.50000000 313.60001  0.30901700  -0.50000000 0.80901699  
119.78454  -0.50000000 -0.80901699 -0.30901700 821.01548  
# 
_pdbx_point_symmetry.entry_id             7X37 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2022-09-28 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.14_3259: 
_software.pdbx_ordinal           1 
# 
_em_3d_fitting.entry_id          7X37 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7X37 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               36573 
_em_3d_reconstruction.resolution                  3.31 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.details              ? 
_em_entity_assembly.name                 'Cryo-EM structure of Coxsackievirus B1 A particle in complex with nAb 2E6 (CVB1-A:2E6)' 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7X37 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI TECNAI F30' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             3500 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7X37 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7X37 
_em_experiment.id                      1 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OG1 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   THR 
_pdbx_validate_close_contact.auth_seq_id_1    108 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   NH2 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   ARG 
_pdbx_validate_close_contact.auth_seq_id_2    248 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             1.59 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER L 14  ? ? -116.19 -163.95 
2  1 ALA L 51  ? ? 67.33   -7.26   
3  1 ALA L 55  ? ? -79.95  -167.02 
4  1 GLN H 3   ? ? -122.26 -168.04 
5  1 SER H 84  ? ? 71.88   -12.09  
6  1 LEU H 85  ? ? 39.15   67.37   
7  1 LYS A 84  ? ? 59.49   1.92    
8  1 LYS A 85  ? ? -141.58 28.13   
9  1 ARG A 95  ? ? -97.55  32.38   
10 1 ALA A 129 ? ? -171.41 -173.80 
11 1 ASN A 208 ? ? 58.58   76.65   
12 1 THR A 209 ? ? -62.81  0.67    
13 1 THR B 25  ? ? -124.26 -169.81 
14 1 ASN B 74  ? ? -96.18  58.90   
15 1 PRO B 83  ? ? -88.00  41.66   
16 1 ASP B 150 ? ? 39.91   40.87   
17 1 ALA B 165 ? ? -64.51  -70.89  
18 1 LYS B 166 ? ? -163.99 113.35  
19 1 ASN B 198 ? ? -131.79 -30.45  
20 1 SER C 10  ? ? -95.50  -64.41  
21 1 THR C 11  ? ? -96.58  58.16   
22 1 ASP C 29  ? ? 59.20   71.53   
23 1 THR C 58  ? ? 37.49   40.60   
24 1 GLU C 59  ? ? 71.55   -11.97  
25 1 SER C 63  ? ? -96.33  50.98   
26 1 ASN C 92  ? ? 43.20   27.51   
27 1 MET C 224 ? ? 60.37   72.88   
28 1 PHE C 230 ? ? -95.70  56.58   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   SER 
_pdbx_validate_peptide_omega.auth_asym_id_1   H 
_pdbx_validate_peptide_omega.auth_seq_id_1    118 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   ARG 
_pdbx_validate_peptide_omega.auth_asym_id_2   H 
_pdbx_validate_peptide_omega.auth_seq_id_2    119 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            147.97 
# 
_pdbx_validate_main_chain_plane.id                       1 
_pdbx_validate_main_chain_plane.PDB_model_num            1 
_pdbx_validate_main_chain_plane.auth_comp_id             SER 
_pdbx_validate_main_chain_plane.auth_asym_id             H 
_pdbx_validate_main_chain_plane.auth_seq_id              118 
_pdbx_validate_main_chain_plane.PDB_ins_code             ? 
_pdbx_validate_main_chain_plane.label_alt_id             ? 
_pdbx_validate_main_chain_plane.improper_torsion_angle   -10.57 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 1   ? C GLY 1   
2   1 Y 1 A PRO 2   ? C PRO 2   
3   1 Y 1 A VAL 3   ? C VAL 3   
4   1 Y 1 A GLU 4   ? C GLU 4   
5   1 Y 1 A GLU 5   ? C GLU 5   
6   1 Y 1 A SER 6   ? C SER 6   
7   1 Y 1 A VAL 7   ? C VAL 7   
8   1 Y 1 A ASP 8   ? C ASP 8   
9   1 Y 1 A ARG 9   ? C ARG 9   
10  1 Y 1 A ALA 10  ? C ALA 10  
11  1 Y 1 A VAL 11  ? C VAL 11  
12  1 Y 1 A ALA 12  ? C ALA 12  
13  1 Y 1 A ARG 13  ? C ARG 13  
14  1 Y 1 A VAL 14  ? C VAL 14  
15  1 Y 1 A ALA 15  ? C ALA 15  
16  1 Y 1 A ASP 16  ? C ASP 16  
17  1 Y 1 A THR 17  ? C THR 17  
18  1 Y 1 A ILE 18  ? C ILE 18  
19  1 Y 1 A SER 19  ? C SER 19  
20  1 Y 1 A SER 20  ? C SER 20  
21  1 Y 1 A ARG 21  ? C ARG 21  
22  1 Y 1 A PRO 22  ? C PRO 22  
23  1 Y 1 A THR 23  ? C THR 23  
24  1 Y 1 A ASN 24  ? C ASN 24  
25  1 Y 1 A SER 25  ? C SER 25  
26  1 Y 1 A GLU 26  ? C GLU 26  
27  1 Y 1 A SER 27  ? C SER 27  
28  1 Y 1 A ILE 28  ? C ILE 28  
29  1 Y 1 A PRO 29  ? C PRO 29  
30  1 Y 1 A ALA 30  ? C ALA 30  
31  1 Y 1 A LEU 31  ? C LEU 31  
32  1 Y 1 A THR 32  ? C THR 32  
33  1 Y 1 A ALA 33  ? C ALA 33  
34  1 Y 1 A ALA 34  ? C ALA 34  
35  1 Y 1 A GLU 35  ? C GLU 35  
36  1 Y 1 A THR 36  ? C THR 36  
37  1 Y 1 A GLY 37  ? C GLY 37  
38  1 Y 1 A HIS 38  ? C HIS 38  
39  1 Y 1 A THR 39  ? C THR 39  
40  1 Y 1 A SER 40  ? C SER 40  
41  1 Y 1 A GLN 41  ? C GLN 41  
42  1 Y 1 A VAL 42  ? C VAL 42  
43  1 Y 1 A VAL 43  ? C VAL 43  
44  1 Y 1 A PRO 44  ? C PRO 44  
45  1 Y 1 A SER 45  ? C SER 45  
46  1 Y 1 A ASP 46  ? C ASP 46  
47  1 Y 1 A THR 47  ? C THR 47  
48  1 Y 1 A MET 48  ? C MET 48  
49  1 Y 1 A GLN 49  ? C GLN 49  
50  1 Y 1 A THR 50  ? C THR 50  
51  1 Y 1 A ARG 51  ? C ARG 51  
52  1 Y 1 A HIS 52  ? C HIS 52  
53  1 Y 1 A VAL 53  ? C VAL 53  
54  1 Y 1 A LYS 54  ? C LYS 54  
55  1 Y 1 A ASN 55  ? C ASN 55  
56  1 Y 1 A TYR 56  ? C TYR 56  
57  1 Y 1 A HIS 57  ? C HIS 57  
58  1 Y 1 A GLN 198 ? C GLN 198 
59  1 Y 1 A PHE 199 ? C PHE 199 
60  1 Y 1 A SER 200 ? C SER 200 
61  1 Y 1 A ARG 201 ? C ARG 201 
62  1 Y 1 A ASN 202 ? C ASN 202 
63  1 Y 1 A GLY 203 ? C GLY 203 
64  1 Y 1 A THR 277 ? C THR 277 
65  1 Y 1 A THR 278 ? C THR 278 
66  1 Y 1 B SER 1   ? D SER 1   
67  1 Y 1 B PRO 2   ? D PRO 2   
68  1 Y 1 B SER 3   ? D SER 3   
69  1 Y 1 B ALA 4   ? D ALA 4   
70  1 Y 1 B GLU 5   ? D GLU 5   
71  1 Y 1 B GLU 6   ? D GLU 6   
72  1 Y 1 B CYS 7   ? D CYS 7   
73  1 Y 1 B GLY 8   ? D GLY 8   
74  1 Y 1 B TYR 9   ? D TYR 9   
75  1 Y 1 B SER 10  ? D SER 10  
76  1 Y 1 B ASP 11  ? D ASP 11  
77  1 Y 1 B ARG 12  ? D ARG 12  
78  1 Y 1 B VAL 13  ? D VAL 13  
79  1 Y 1 B GLU 27  ? D GLU 27  
80  1 Y 1 B CYS 28  ? D CYS 28  
81  1 Y 1 B ALA 29  ? D ALA 29  
82  1 Y 1 B LYS 43  ? D LYS 43  
83  1 Y 1 B ASP 44  ? D ASP 44  
84  1 Y 1 B ASN 45  ? D ASN 45  
85  1 Y 1 B GLU 46  ? D GLU 46  
86  1 Y 1 B ALA 47  ? D ALA 47  
87  1 Y 1 B THR 48  ? D THR 48  
88  1 Y 1 B ALA 49  ? D ALA 49  
89  1 Y 1 B GLU 50  ? D GLU 50  
90  1 Y 1 B ARG 258 ? D ARG 258 
91  1 Y 1 B LEU 259 ? D LEU 259 
92  1 Y 1 B ALA 260 ? D ALA 260 
93  1 Y 1 B SER 261 ? D SER 261 
94  1 Y 1 B ASN 262 ? D ASN 262 
95  1 Y 1 B GLN 263 ? D GLN 263 
96  1 Y 1 C GLN 173 ? E GLN 173 
97  1 Y 1 C THR 174 ? E THR 174 
98  1 Y 1 C HIS 175 ? E HIS 175 
99  1 Y 1 C TYR 176 ? E TYR 176 
100 1 Y 1 C ARG 177 ? E ARG 177 
101 1 Y 1 C TYR 178 ? E TYR 178 
102 1 Y 1 C VAL 179 ? E VAL 179 
103 1 Y 1 C VAL 180 ? E VAL 180 
104 1 Y 1 C GLU 181 ? E GLU 181 
105 1 Y 1 C ASP 182 ? E ASP 182 
106 1 Y 1 C GLU 183 ? E GLU 183 
107 1 Y 1 C TYR 184 ? E TYR 184 
108 1 Y 1 C THR 185 ? E THR 185 
109 1 Y 1 C GLN 233 ? E GLN 233 
110 1 Y 1 C ASP 234 ? E ASP 234 
111 1 Y 1 C THR 235 ? E THR 235 
112 1 Y 1 C PHE 236 ? E PHE 236 
113 1 Y 1 C TYR 237 ? E TYR 237 
114 1 Y 1 C GLN 238 ? E GLN 238 
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.ncbi_tax_id          12071 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organism             'Coxsackievirus B1' 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.ncbi_tax_id          10029 
_em_entity_assembly_recombinant.organism             'Cricetulus griseus' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       INTEGRATING 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'PARTICLE SELECTION'       ? ? ? 1 ? ? 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
