data_7X38
# 
_entry.id   7X38 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.360 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7X38         pdb_00007x38 10.2210/pdb7x38/pdb 
WWPDB D_1300027913 ?            ?                   
EMDB  EMD-32981    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 8A10 (CVB1-E:8A10)' 
_pdbx_database_related.db_id          EMD-32981 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7X38 
_pdbx_database_status.recvd_initial_deposition_date   2022-02-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zheng, Q.' 1 ? 
'Zhu, R.'   2 ? 
'Sun, H.'   3 ? 
'Cheng, T.' 4 ? 
'Li, S.'    5 ? 
'Xia, N.'   6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Host Microbe' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1934-6069 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            30 
_citation.language                  ? 
_citation.page_first                1279 
_citation.page_last                 1294.e6 
_citation.title                     
'Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.' 
_citation.year                      2022 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.chom.2022.08.001 
_citation.pdbx_database_id_PubMed   36002016 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zheng, Q.' 1  ? 
primary 'Zhu, R.'   2  ? 
primary 'Yin, Z.'   3  ? 
primary 'Xu, L.'    4  ? 
primary 'Sun, H.'   5  ? 
primary 'Yu, H.'    6  ? 
primary 'Wu, Y.'    7  ? 
primary 'Jiang, Y.' 8  ? 
primary 'Huang, Q.' 9  ? 
primary 'Huang, Y.' 10 ? 
primary 'Zhang, D.' 11 ? 
primary 'Liu, L.'   12 ? 
primary 'Yang, H.'  13 ? 
primary 'He, M.'    14 ? 
primary 'Zhou, Z.'  15 ? 
primary 'Jiang, Y.' 16 ? 
primary 'Chen, Z.'  17 ? 
primary 'Zhao, H.'  18 ? 
primary 'Que, Y.'   19 ? 
primary 'Kong, Z.'  20 ? 
primary 'Zhou, L.'  21 ? 
primary 'Li, T.'    22 ? 
primary 'Zhang, J.' 23 ? 
primary 'Luo, W.'   24 ? 
primary 'Gu, Y.'    25 ? 
primary 'Cheng, T.' 26 ? 
primary 'Li, S.'    27 ? 
primary 'Xia, N.'   28 ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7X38 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         7X38 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer nat '8A10 light chain' 11945.163 1 ?                                     ? ? ? 
2 polymer nat '8A10 heavy chain' 13323.863 1 ?                                     ? ? ? 
3 polymer nat 'Virion protein 1' 31207.117 1 ?                                     ? ? ? 
4 polymer nat VP2                29122.744 1 ?                                     ? ? ? 
5 polymer nat VP3                26328.764 1 3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48 ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'VP1, P1C,P1D' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DIQMTQTKSSLSASLGDRVTISCRASQDISNYLNWYQQKPDGSVKLLIYYTSTLHSGVPSRFSGSGSGTDYSLTINSLEQ
EDIATYFCQQGNTFPFTFGGGTKLEIRR
;
;DIQMTQTKSSLSASLGDRVTISCRASQDISNYLNWYQQKPDGSVKLLIYYTSTLHSGVPSRFSGSGSGTDYSLTINSLEQ
EDIATYFCQQGNTFPFTFGGGTKLEIRR
;
L ? 
2 'polypeptide(L)' no no 
;QVQLQQSAAELARPGASVKMSCKASGYTFTTYTMHWVKQRPGQGLEWIGYINPSSRYTEYNQKFKDKTTLTADKSSSTAY
MQLSSLTFEDSAVYYCARRSEADRFVYWGQGTLVTVSA
;
;QVQLQQSAAELARPGASVKMSCKASGYTFTTYTMHWVKQRPGQGLEWIGYINPSSRYTEYNQKFKDKTTLTADKSSSTAY
MQLSSLTFEDSAVYYCARRSEADRFVYWGQGTLVTVSA
;
H ? 
3 'polypeptide(L)' no no 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
A ? 
4 'polypeptide(L)' no no 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
B ? 
5 'polypeptide(L)' no no 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   ILE n 
1 3   GLN n 
1 4   MET n 
1 5   THR n 
1 6   GLN n 
1 7   THR n 
1 8   LYS n 
1 9   SER n 
1 10  SER n 
1 11  LEU n 
1 12  SER n 
1 13  ALA n 
1 14  SER n 
1 15  LEU n 
1 16  GLY n 
1 17  ASP n 
1 18  ARG n 
1 19  VAL n 
1 20  THR n 
1 21  ILE n 
1 22  SER n 
1 23  CYS n 
1 24  ARG n 
1 25  ALA n 
1 26  SER n 
1 27  GLN n 
1 28  ASP n 
1 29  ILE n 
1 30  SER n 
1 31  ASN n 
1 32  TYR n 
1 33  LEU n 
1 34  ASN n 
1 35  TRP n 
1 36  TYR n 
1 37  GLN n 
1 38  GLN n 
1 39  LYS n 
1 40  PRO n 
1 41  ASP n 
1 42  GLY n 
1 43  SER n 
1 44  VAL n 
1 45  LYS n 
1 46  LEU n 
1 47  LEU n 
1 48  ILE n 
1 49  TYR n 
1 50  TYR n 
1 51  THR n 
1 52  SER n 
1 53  THR n 
1 54  LEU n 
1 55  HIS n 
1 56  SER n 
1 57  GLY n 
1 58  VAL n 
1 59  PRO n 
1 60  SER n 
1 61  ARG n 
1 62  PHE n 
1 63  SER n 
1 64  GLY n 
1 65  SER n 
1 66  GLY n 
1 67  SER n 
1 68  GLY n 
1 69  THR n 
1 70  ASP n 
1 71  TYR n 
1 72  SER n 
1 73  LEU n 
1 74  THR n 
1 75  ILE n 
1 76  ASN n 
1 77  SER n 
1 78  LEU n 
1 79  GLU n 
1 80  GLN n 
1 81  GLU n 
1 82  ASP n 
1 83  ILE n 
1 84  ALA n 
1 85  THR n 
1 86  TYR n 
1 87  PHE n 
1 88  CYS n 
1 89  GLN n 
1 90  GLN n 
1 91  GLY n 
1 92  ASN n 
1 93  THR n 
1 94  PHE n 
1 95  PRO n 
1 96  PHE n 
1 97  THR n 
1 98  PHE n 
1 99  GLY n 
1 100 GLY n 
1 101 GLY n 
1 102 THR n 
1 103 LYS n 
1 104 LEU n 
1 105 GLU n 
1 106 ILE n 
1 107 ARG n 
1 108 ARG n 
2 1   GLN n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   GLN n 
2 6   GLN n 
2 7   SER n 
2 8   ALA n 
2 9   ALA n 
2 10  GLU n 
2 11  LEU n 
2 12  ALA n 
2 13  ARG n 
2 14  PRO n 
2 15  GLY n 
2 16  ALA n 
2 17  SER n 
2 18  VAL n 
2 19  LYS n 
2 20  MET n 
2 21  SER n 
2 22  CYS n 
2 23  LYS n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  TYR n 
2 28  THR n 
2 29  PHE n 
2 30  THR n 
2 31  THR n 
2 32  TYR n 
2 33  THR n 
2 34  MET n 
2 35  HIS n 
2 36  TRP n 
2 37  VAL n 
2 38  LYS n 
2 39  GLN n 
2 40  ARG n 
2 41  PRO n 
2 42  GLY n 
2 43  GLN n 
2 44  GLY n 
2 45  LEU n 
2 46  GLU n 
2 47  TRP n 
2 48  ILE n 
2 49  GLY n 
2 50  TYR n 
2 51  ILE n 
2 52  ASN n 
2 53  PRO n 
2 54  SER n 
2 55  SER n 
2 56  ARG n 
2 57  TYR n 
2 58  THR n 
2 59  GLU n 
2 60  TYR n 
2 61  ASN n 
2 62  GLN n 
2 63  LYS n 
2 64  PHE n 
2 65  LYS n 
2 66  ASP n 
2 67  LYS n 
2 68  THR n 
2 69  THR n 
2 70  LEU n 
2 71  THR n 
2 72  ALA n 
2 73  ASP n 
2 74  LYS n 
2 75  SER n 
2 76  SER n 
2 77  SER n 
2 78  THR n 
2 79  ALA n 
2 80  TYR n 
2 81  MET n 
2 82  GLN n 
2 83  LEU n 
2 84  SER n 
2 85  SER n 
2 86  LEU n 
2 87  THR n 
2 88  PHE n 
2 89  GLU n 
2 90  ASP n 
2 91  SER n 
2 92  ALA n 
2 93  VAL n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  ALA n 
2 98  ARG n 
2 99  ARG n 
2 100 SER n 
2 101 GLU n 
2 102 ALA n 
2 103 ASP n 
2 104 ARG n 
2 105 PHE n 
2 106 VAL n 
2 107 TYR n 
2 108 TRP n 
2 109 GLY n 
2 110 GLN n 
2 111 GLY n 
2 112 THR n 
2 113 LEU n 
2 114 VAL n 
2 115 THR n 
2 116 VAL n 
2 117 SER n 
2 118 ALA n 
3 1   GLY n 
3 2   PRO n 
3 3   VAL n 
3 4   GLU n 
3 5   GLU n 
3 6   SER n 
3 7   VAL n 
3 8   ASP n 
3 9   ARG n 
3 10  ALA n 
3 11  VAL n 
3 12  ALA n 
3 13  ARG n 
3 14  VAL n 
3 15  ALA n 
3 16  ASP n 
3 17  THR n 
3 18  ILE n 
3 19  SER n 
3 20  SER n 
3 21  ARG n 
3 22  PRO n 
3 23  THR n 
3 24  ASN n 
3 25  SER n 
3 26  GLU n 
3 27  SER n 
3 28  ILE n 
3 29  PRO n 
3 30  ALA n 
3 31  LEU n 
3 32  THR n 
3 33  ALA n 
3 34  ALA n 
3 35  GLU n 
3 36  THR n 
3 37  GLY n 
3 38  HIS n 
3 39  THR n 
3 40  SER n 
3 41  GLN n 
3 42  VAL n 
3 43  VAL n 
3 44  PRO n 
3 45  SER n 
3 46  ASP n 
3 47  THR n 
3 48  MET n 
3 49  GLN n 
3 50  THR n 
3 51  ARG n 
3 52  HIS n 
3 53  VAL n 
3 54  LYS n 
3 55  ASN n 
3 56  TYR n 
3 57  HIS n 
3 58  SER n 
3 59  ARG n 
3 60  SER n 
3 61  GLU n 
3 62  SER n 
3 63  SER n 
3 64  ILE n 
3 65  GLU n 
3 66  ASN n 
3 67  PHE n 
3 68  LEU n 
3 69  CYS n 
3 70  ARG n 
3 71  SER n 
3 72  ALA n 
3 73  CYS n 
3 74  VAL n 
3 75  TYR n 
3 76  TYR n 
3 77  ALA n 
3 78  THR n 
3 79  TYR n 
3 80  THR n 
3 81  ASN n 
3 82  ASN n 
3 83  SER n 
3 84  LYS n 
3 85  LYS n 
3 86  GLY n 
3 87  PHE n 
3 88  ALA n 
3 89  GLU n 
3 90  TRP n 
3 91  VAL n 
3 92  ILE n 
3 93  ASN n 
3 94  THR n 
3 95  ARG n 
3 96  GLN n 
3 97  VAL n 
3 98  ALA n 
3 99  GLN n 
3 100 LEU n 
3 101 ARG n 
3 102 ARG n 
3 103 LYS n 
3 104 LEU n 
3 105 GLU n 
3 106 LEU n 
3 107 PHE n 
3 108 THR n 
3 109 TYR n 
3 110 LEU n 
3 111 ARG n 
3 112 PHE n 
3 113 ASP n 
3 114 LEU n 
3 115 GLU n 
3 116 LEU n 
3 117 THR n 
3 118 PHE n 
3 119 VAL n 
3 120 ILE n 
3 121 THR n 
3 122 SER n 
3 123 ALA n 
3 124 GLN n 
3 125 GLN n 
3 126 PRO n 
3 127 SER n 
3 128 THR n 
3 129 ALA n 
3 130 SER n 
3 131 SER n 
3 132 VAL n 
3 133 ASP n 
3 134 ALA n 
3 135 PRO n 
3 136 VAL n 
3 137 GLN n 
3 138 THR n 
3 139 HIS n 
3 140 GLN n 
3 141 ILE n 
3 142 MET n 
3 143 TYR n 
3 144 VAL n 
3 145 PRO n 
3 146 PRO n 
3 147 GLY n 
3 148 GLY n 
3 149 PRO n 
3 150 VAL n 
3 151 PRO n 
3 152 THR n 
3 153 LYS n 
3 154 VAL n 
3 155 LYS n 
3 156 ASP n 
3 157 TYR n 
3 158 ALA n 
3 159 TRP n 
3 160 GLN n 
3 161 THR n 
3 162 SER n 
3 163 THR n 
3 164 ASN n 
3 165 PRO n 
3 166 SER n 
3 167 VAL n 
3 168 PHE n 
3 169 TRP n 
3 170 THR n 
3 171 GLU n 
3 172 GLY n 
3 173 ASN n 
3 174 ALA n 
3 175 PRO n 
3 176 PRO n 
3 177 ARG n 
3 178 MET n 
3 179 SER n 
3 180 ILE n 
3 181 PRO n 
3 182 PHE n 
3 183 ILE n 
3 184 SER n 
3 185 ILE n 
3 186 GLY n 
3 187 ASN n 
3 188 ALA n 
3 189 TYR n 
3 190 SER n 
3 191 CYS n 
3 192 PHE n 
3 193 TYR n 
3 194 ASP n 
3 195 GLY n 
3 196 TRP n 
3 197 THR n 
3 198 GLN n 
3 199 PHE n 
3 200 SER n 
3 201 ARG n 
3 202 ASN n 
3 203 GLY n 
3 204 VAL n 
3 205 TYR n 
3 206 GLY n 
3 207 ILE n 
3 208 ASN n 
3 209 THR n 
3 210 LEU n 
3 211 ASN n 
3 212 ASN n 
3 213 MET n 
3 214 GLY n 
3 215 THR n 
3 216 LEU n 
3 217 TYR n 
3 218 MET n 
3 219 ARG n 
3 220 HIS n 
3 221 VAL n 
3 222 ASN n 
3 223 GLU n 
3 224 ALA n 
3 225 GLY n 
3 226 GLN n 
3 227 GLY n 
3 228 PRO n 
3 229 ILE n 
3 230 LYS n 
3 231 SER n 
3 232 THR n 
3 233 VAL n 
3 234 ARG n 
3 235 ILE n 
3 236 TYR n 
3 237 PHE n 
3 238 LYS n 
3 239 PRO n 
3 240 LYS n 
3 241 HIS n 
3 242 VAL n 
3 243 LYS n 
3 244 ALA n 
3 245 TRP n 
3 246 VAL n 
3 247 PRO n 
3 248 ARG n 
3 249 PRO n 
3 250 PRO n 
3 251 ARG n 
3 252 LEU n 
3 253 CYS n 
3 254 GLN n 
3 255 TYR n 
3 256 GLU n 
3 257 LYS n 
3 258 GLN n 
3 259 LYS n 
3 260 ASN n 
3 261 VAL n 
3 262 ASN n 
3 263 PHE n 
3 264 SER n 
3 265 PRO n 
3 266 ILE n 
3 267 GLY n 
3 268 VAL n 
3 269 THR n 
3 270 THR n 
3 271 SER n 
3 272 ARG n 
3 273 THR n 
3 274 ASP n 
3 275 ILE n 
3 276 ILE n 
3 277 THR n 
3 278 THR n 
4 1   SER n 
4 2   PRO n 
4 3   SER n 
4 4   ALA n 
4 5   GLU n 
4 6   GLU n 
4 7   CYS n 
4 8   GLY n 
4 9   TYR n 
4 10  SER n 
4 11  ASP n 
4 12  ARG n 
4 13  VAL n 
4 14  ARG n 
4 15  SER n 
4 16  ILE n 
4 17  THR n 
4 18  LEU n 
4 19  GLY n 
4 20  ASN n 
4 21  SER n 
4 22  THR n 
4 23  ILE n 
4 24  THR n 
4 25  THR n 
4 26  GLN n 
4 27  GLU n 
4 28  CYS n 
4 29  ALA n 
4 30  ASN n 
4 31  VAL n 
4 32  VAL n 
4 33  VAL n 
4 34  GLY n 
4 35  TYR n 
4 36  GLY n 
4 37  VAL n 
4 38  TRP n 
4 39  PRO n 
4 40  GLU n 
4 41  TYR n 
4 42  LEU n 
4 43  LYS n 
4 44  ASP n 
4 45  ASN n 
4 46  GLU n 
4 47  ALA n 
4 48  THR n 
4 49  ALA n 
4 50  GLU n 
4 51  ASP n 
4 52  GLN n 
4 53  PRO n 
4 54  THR n 
4 55  GLN n 
4 56  PRO n 
4 57  ASP n 
4 58  VAL n 
4 59  ALA n 
4 60  THR n 
4 61  CYS n 
4 62  ARG n 
4 63  PHE n 
4 64  TYR n 
4 65  THR n 
4 66  LEU n 
4 67  GLU n 
4 68  SER n 
4 69  VAL n 
4 70  GLN n 
4 71  TRP n 
4 72  MET n 
4 73  LYS n 
4 74  ASN n 
4 75  SER n 
4 76  ALA n 
4 77  GLY n 
4 78  TRP n 
4 79  TRP n 
4 80  TRP n 
4 81  LYS n 
4 82  LEU n 
4 83  PRO n 
4 84  ASP n 
4 85  ALA n 
4 86  LEU n 
4 87  SER n 
4 88  GLN n 
4 89  MET n 
4 90  GLY n 
4 91  LEU n 
4 92  PHE n 
4 93  GLY n 
4 94  GLN n 
4 95  ASN n 
4 96  MET n 
4 97  GLN n 
4 98  TYR n 
4 99  HIS n 
4 100 TYR n 
4 101 LEU n 
4 102 GLY n 
4 103 ARG n 
4 104 THR n 
4 105 GLY n 
4 106 TYR n 
4 107 THR n 
4 108 ILE n 
4 109 HIS n 
4 110 VAL n 
4 111 GLN n 
4 112 CYS n 
4 113 ASN n 
4 114 ALA n 
4 115 SER n 
4 116 LYS n 
4 117 PHE n 
4 118 HIS n 
4 119 GLN n 
4 120 GLY n 
4 121 CYS n 
4 122 LEU n 
4 123 LEU n 
4 124 VAL n 
4 125 VAL n 
4 126 CYS n 
4 127 VAL n 
4 128 PRO n 
4 129 GLU n 
4 130 ALA n 
4 131 GLU n 
4 132 MET n 
4 133 GLY n 
4 134 CYS n 
4 135 SER n 
4 136 ASN n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 THR n 
4 141 PRO n 
4 142 GLU n 
4 143 PHE n 
4 144 SER n 
4 145 GLU n 
4 146 LEU n 
4 147 SER n 
4 148 GLY n 
4 149 GLY n 
4 150 ASP n 
4 151 SER n 
4 152 ALA n 
4 153 ARG n 
4 154 MET n 
4 155 PHE n 
4 156 THR n 
4 157 ASP n 
4 158 THR n 
4 159 GLN n 
4 160 VAL n 
4 161 GLY n 
4 162 GLU n 
4 163 SER n 
4 164 ASN n 
4 165 ALA n 
4 166 LYS n 
4 167 LYS n 
4 168 VAL n 
4 169 GLN n 
4 170 THR n 
4 171 ALA n 
4 172 VAL n 
4 173 TRP n 
4 174 ASN n 
4 175 ALA n 
4 176 GLY n 
4 177 MET n 
4 178 GLY n 
4 179 VAL n 
4 180 GLY n 
4 181 VAL n 
4 182 GLY n 
4 183 ASN n 
4 184 LEU n 
4 185 THR n 
4 186 ILE n 
4 187 PHE n 
4 188 PRO n 
4 189 HIS n 
4 190 GLN n 
4 191 TRP n 
4 192 ILE n 
4 193 ASN n 
4 194 LEU n 
4 195 ARG n 
4 196 THR n 
4 197 ASN n 
4 198 ASN n 
4 199 SER n 
4 200 ALA n 
4 201 THR n 
4 202 LEU n 
4 203 VAL n 
4 204 MET n 
4 205 PRO n 
4 206 TYR n 
4 207 ILE n 
4 208 ASN n 
4 209 SER n 
4 210 VAL n 
4 211 PRO n 
4 212 MET n 
4 213 ASP n 
4 214 ASN n 
4 215 MET n 
4 216 PHE n 
4 217 ARG n 
4 218 HIS n 
4 219 ASN n 
4 220 ASN n 
4 221 LEU n 
4 222 THR n 
4 223 LEU n 
4 224 MET n 
4 225 ILE n 
4 226 ILE n 
4 227 PRO n 
4 228 PHE n 
4 229 VAL n 
4 230 PRO n 
4 231 LEU n 
4 232 ASN n 
4 233 TYR n 
4 234 SER n 
4 235 GLU n 
4 236 GLY n 
4 237 SER n 
4 238 SER n 
4 239 PRO n 
4 240 TYR n 
4 241 VAL n 
4 242 PRO n 
4 243 ILE n 
4 244 THR n 
4 245 VAL n 
4 246 THR n 
4 247 ILE n 
4 248 ALA n 
4 249 PRO n 
4 250 MET n 
4 251 CYS n 
4 252 ALA n 
4 253 GLU n 
4 254 TYR n 
4 255 ASN n 
4 256 GLY n 
4 257 LEU n 
4 258 ARG n 
4 259 LEU n 
4 260 ALA n 
4 261 SER n 
4 262 ASN n 
4 263 GLN n 
5 1   GLY n 
5 2   LEU n 
5 3   PRO n 
5 4   VAL n 
5 5   MET n 
5 6   THR n 
5 7   THR n 
5 8   PRO n 
5 9   GLY n 
5 10  SER n 
5 11  THR n 
5 12  GLN n 
5 13  PHE n 
5 14  LEU n 
5 15  THR n 
5 16  SER n 
5 17  ASP n 
5 18  ASP n 
5 19  PHE n 
5 20  GLN n 
5 21  SER n 
5 22  PRO n 
5 23  SER n 
5 24  ALA n 
5 25  MET n 
5 26  PRO n 
5 27  GLN n 
5 28  PHE n 
5 29  ASP n 
5 30  VAL n 
5 31  THR n 
5 32  PRO n 
5 33  GLU n 
5 34  MET n 
5 35  GLN n 
5 36  ILE n 
5 37  PRO n 
5 38  GLY n 
5 39  ARG n 
5 40  VAL n 
5 41  ASN n 
5 42  ASN n 
5 43  LEU n 
5 44  MET n 
5 45  GLU n 
5 46  ILE n 
5 47  ALA n 
5 48  GLU n 
5 49  VAL n 
5 50  ASP n 
5 51  SER n 
5 52  VAL n 
5 53  VAL n 
5 54  PRO n 
5 55  VAL n 
5 56  ASN n 
5 57  ASN n 
5 58  THR n 
5 59  GLU n 
5 60  ASP n 
5 61  ASN n 
5 62  VAL n 
5 63  SER n 
5 64  SER n 
5 65  LEU n 
5 66  LYS n 
5 67  ALA n 
5 68  TYR n 
5 69  GLN n 
5 70  ILE n 
5 71  PRO n 
5 72  VAL n 
5 73  GLN n 
5 74  SER n 
5 75  ASN n 
5 76  SER n 
5 77  ASP n 
5 78  ASN n 
5 79  GLY n 
5 80  LYS n 
5 81  GLN n 
5 82  VAL n 
5 83  PHE n 
5 84  GLY n 
5 85  PHE n 
5 86  PRO n 
5 87  LEU n 
5 88  GLN n 
5 89  PRO n 
5 90  GLY n 
5 91  ALA n 
5 92  ASN n 
5 93  ASN n 
5 94  VAL n 
5 95  LEU n 
5 96  ASN n 
5 97  ARG n 
5 98  THR n 
5 99  LEU n 
5 100 LEU n 
5 101 GLY n 
5 102 GLU n 
5 103 ILE n 
5 104 LEU n 
5 105 ASN n 
5 106 TYR n 
5 107 TYR n 
5 108 THR n 
5 109 HIS n 
5 110 TRP n 
5 111 SER n 
5 112 GLY n 
5 113 SER n 
5 114 ILE n 
5 115 LYS n 
5 116 LEU n 
5 117 THR n 
5 118 PHE n 
5 119 MET n 
5 120 PHE n 
5 121 CYS n 
5 122 GLY n 
5 123 SER n 
5 124 ALA n 
5 125 MET n 
5 126 ALA n 
5 127 THR n 
5 128 GLY n 
5 129 LYS n 
5 130 PHE n 
5 131 LEU n 
5 132 LEU n 
5 133 ALA n 
5 134 TYR n 
5 135 SER n 
5 136 PRO n 
5 137 PRO n 
5 138 GLY n 
5 139 ALA n 
5 140 GLY n 
5 141 VAL n 
5 142 PRO n 
5 143 LYS n 
5 144 ASN n 
5 145 ARG n 
5 146 LYS n 
5 147 ASP n 
5 148 ALA n 
5 149 MET n 
5 150 LEU n 
5 151 GLY n 
5 152 THR n 
5 153 HIS n 
5 154 VAL n 
5 155 ILE n 
5 156 TRP n 
5 157 ASP n 
5 158 VAL n 
5 159 GLY n 
5 160 LEU n 
5 161 GLN n 
5 162 SER n 
5 163 SER n 
5 164 CYS n 
5 165 VAL n 
5 166 LEU n 
5 167 CYS n 
5 168 VAL n 
5 169 PRO n 
5 170 TRP n 
5 171 ILE n 
5 172 SER n 
5 173 GLN n 
5 174 THR n 
5 175 HIS n 
5 176 TYR n 
5 177 ARG n 
5 178 TYR n 
5 179 VAL n 
5 180 VAL n 
5 181 GLU n 
5 182 ASP n 
5 183 GLU n 
5 184 TYR n 
5 185 THR n 
5 186 ALA n 
5 187 ALA n 
5 188 GLY n 
5 189 TYR n 
5 190 VAL n 
5 191 THR n 
5 192 CYS n 
5 193 TRP n 
5 194 TYR n 
5 195 GLN n 
5 196 THR n 
5 197 ASN n 
5 198 ILE n 
5 199 VAL n 
5 200 VAL n 
5 201 PRO n 
5 202 ALA n 
5 203 ASP n 
5 204 VAL n 
5 205 GLN n 
5 206 SER n 
5 207 SER n 
5 208 CYS n 
5 209 ASP n 
5 210 ILE n 
5 211 LEU n 
5 212 CYS n 
5 213 PHE n 
5 214 VAL n 
5 215 SER n 
5 216 ALA n 
5 217 CYS n 
5 218 ASN n 
5 219 ASP n 
5 220 PHE n 
5 221 SER n 
5 222 VAL n 
5 223 ARG n 
5 224 MET n 
5 225 LEU n 
5 226 LYS n 
5 227 ASP n 
5 228 THR n 
5 229 PRO n 
5 230 PHE n 
5 231 ILE n 
5 232 ARG n 
5 233 GLN n 
5 234 ASP n 
5 235 THR n 
5 236 PHE n 
5 237 TYR n 
5 238 GLN n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 108 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 118 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 1 278 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 263 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 1 238 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7X38             7X38       ? 1 ? 1   
2 PDB 7X38             7X38       ? 2 ? 1   
3 UNP W8GTF7_9ENTO     W8GTF7     ? 3 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSEKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
1   
4 UNP A0A2S0RQC2_9ENTO A0A2S0RQC2 ? 4 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
70  
5 UNP L7UV52_9ENTO     L7UV52     ? 5 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7X38 L 1 ? 108 ? 7X38       1   ? 108 ? 1 108 
2 2 7X38 H 1 ? 118 ? 7X38       1   ? 118 ? 1 118 
3 3 7X38 A 1 ? 278 ? W8GTF7     1   ? 278 ? 1 278 
4 4 7X38 B 1 ? 263 ? A0A2S0RQC2 70  ? 332 ? 1 263 
5 5 7X38 C 1 ? 238 ? L7UV52     333 ? 570 ? 1 238 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             7X38 
_struct_ref_seq_dif.mon_id                       LYS 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      84 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   W8GTF7 
_struct_ref_seq_dif.db_mon_id                    GLU 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          84 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            84 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7X38 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7X38 
_struct.title                        'Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 8A10 (CVB1-E:8A10)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7X38 
_struct_keywords.text            'Coxsackievirus B1, Neutralizing antibody, Cryo-EM, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN B 62  ? LYS B 65  ? GLN H 62  LYS H 65  5 ? 4 
HELX_P HELX_P2  AA2 ILE C 64  ? CYS C 69  ? ILE A 64  CYS A 69  1 ? 6 
HELX_P HELX_P3  AA3 VAL C 97  ? GLU C 105 ? VAL A 97  GLU A 105 1 ? 9 
HELX_P HELX_P4  AA4 LEU D 82  ? LEU D 86  ? LEU B 82  LEU B 86  1 ? 5 
HELX_P HELX_P5  AA5 MET D 89  ? GLN D 94  ? MET B 89  GLN B 94  1 ? 6 
HELX_P HELX_P6  AA6 GLN D 94  ? HIS D 99  ? GLN B 94  HIS B 99  1 ? 6 
HELX_P HELX_P7  AA7 GLU D 142 ? SER D 147 ? GLU B 142 SER B 147 1 ? 6 
HELX_P HELX_P8  AA8 ALA D 171 ? ALA D 175 ? ALA B 171 ALA B 175 5 ? 5 
HELX_P HELX_P9  AA9 GLY D 180 ? PHE D 187 ? GLY B 180 PHE B 187 5 ? 8 
HELX_P HELX_P10 AB1 LEU E 43  ? GLU E 48  ? LEU C 43  GLU C 48  1 ? 6 
HELX_P HELX_P11 AB2 SER E 64  ? TYR E 68  ? SER C 64  TYR C 68  5 ? 5 
HELX_P HELX_P12 AB3 ILE E 103 ? ASN E 105 ? ILE C 103 ASN C 105 5 ? 3 
HELX_P HELX_P13 AB4 ASN E 144 ? LEU E 150 ? ASN C 144 LEU C 150 1 ? 7 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 23 SG ? ? ? 1_555 A CYS 88 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf2 disulf ? ? B CYS 22 SG ? ? ? 1_555 B CYS 96 SG ? ? H CYS 22 H CYS 96 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          PHE 
_struct_mon_prot_cis.label_seq_id           94 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           PHE 
_struct_mon_prot_cis.auth_seq_id            94 
_struct_mon_prot_cis.auth_asym_id           L 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    95 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     95 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    L 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -1.10 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 7 ? 
AA5 ? 7 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 5 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 7 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 2 5 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 5 7 ? anti-parallel 
AA5 1 6 ? anti-parallel 
AA5 2 4 ? anti-parallel 
AA5 2 5 ? anti-parallel 
AA5 2 6 ? anti-parallel 
AA5 3 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 5 ? parallel      
AA8 2 6 ? anti-parallel 
AA8 3 6 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 4 6 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 5 ? anti-parallel 
AB1 2 5 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 3 5 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 22  ? ARG A 24  ? SER L 22  ARG L 24  
AA1 2 ASP A 70  ? ILE A 75  ? ASP L 70  ILE L 75  
AA1 3 PHE A 62  ? SER A 67  ? PHE L 62  SER L 67  
AA2 1 VAL A 44  ? ILE A 48  ? VAL L 44  ILE L 48  
AA2 2 LEU A 33  ? GLN A 38  ? LEU L 33  GLN L 38  
AA2 3 THR A 85  ? GLN A 90  ? THR L 85  GLN L 90  
AA3 1 LEU B 4   ? GLN B 6   ? LEU H 4   GLN H 6   
AA3 2 VAL B 18  ? ALA B 24  ? VAL H 18  ALA H 24  
AA3 3 THR B 78  ? LEU B 83  ? THR H 78  LEU H 83  
AA3 4 THR B 69  ? ASP B 73  ? THR H 69  ASP H 73  
AA4 1 GLU B 10  ? ALA B 12  ? GLU H 10  ALA H 12  
AA4 2 MET B 34  ? GLN B 39  ? MET H 34  GLN H 39  
AA4 3 LEU B 45  ? ILE B 51  ? LEU H 45  ILE H 51  
AA4 4 THR B 58  ? TYR B 60  ? THR H 58  TYR H 60  
AA4 5 ALA B 92  ? SER B 100 ? ALA H 92  SER H 100 
AA4 6 ARG B 104 ? TRP B 108 ? ARG H 104 TRP H 108 
AA4 7 THR B 112 ? VAL B 116 ? THR H 112 VAL H 116 
AA5 1 ALA C 72  ? THR C 80  ? ALA A 72  THR A 80  
AA5 2 PHE C 107 ? ILE C 120 ? PHE A 107 ILE A 120 
AA5 3 ALA C 123 ? GLN C 124 ? ALA A 123 GLN A 124 
AA5 4 MET C 178 ? ILE C 180 ? MET A 178 ILE A 180 
AA5 5 TYR C 189 ? SER C 190 ? TYR A 189 SER A 190 
AA5 6 ILE C 229 ? PRO C 247 ? ILE A 229 PRO A 247 
AA5 7 ARG E 39  ? VAL E 40  ? ARG C 39  VAL C 40  
AA6 1 ALA C 88  ? VAL C 91  ? ALA A 88  VAL A 91  
AA6 2 THR C 215 ? HIS C 220 ? THR A 215 HIS A 220 
AA6 3 THR C 138 ? VAL C 144 ? THR A 138 VAL A 144 
AA6 4 SER C 166 ? THR C 170 ? SER A 166 THR A 170 
AA7 1 ILE D 16  ? THR D 17  ? ILE B 16  THR B 17  
AA7 2 THR D 22  ? ILE D 23  ? THR B 22  ILE B 23  
AA8 1 VAL D 32  ? VAL D 33  ? VAL B 32  VAL B 33  
AA8 2 TYR D 64  ? THR D 65  ? TYR B 64  THR B 65  
AA8 3 VAL D 69  ? TRP D 71  ? VAL B 69  TRP B 71  
AA8 4 ARG D 103 ? CYS D 112 ? ARG B 103 CYS B 112 
AA8 5 SER D 199 ? MET D 204 ? SER B 199 MET B 204 
AA8 6 VAL D 241 ? GLU D 253 ? VAL B 241 GLU B 253 
AA9 1 TRP D 78  ? LYS D 81  ? TRP B 78  LYS B 81  
AA9 2 THR D 222 ? ASN D 232 ? THR B 222 ASN B 232 
AA9 3 GLN D 119 ? VAL D 127 ? GLN B 119 VAL B 127 
AA9 4 TRP D 191 ? ASN D 193 ? TRP B 191 ASN B 193 
AB1 1 SER E 51  ? VAL E 52  ? SER C 51  VAL C 52  
AB1 2 ILE E 70  ? VAL E 72  ? ILE C 70  VAL C 72  
AB1 3 SER E 111 ? CYS E 121 ? SER C 111 CYS C 121 
AB1 4 VAL E 165 ? ILE E 171 ? VAL C 165 ILE C 171 
AB1 5 CYS E 208 ? ALA E 216 ? CYS C 208 ALA C 216 
AB2 1 GLN E 81  ? PHE E 83  ? GLN C 81  PHE C 83  
AB2 2 CYS E 192 ? TYR E 194 ? CYS C 192 TYR C 194 
AB2 3 LYS E 129 ? TYR E 134 ? LYS C 129 TYR C 134 
AB2 4 THR E 152 ? ASP E 157 ? THR C 152 ASP C 157 
AB3 1 TYR E 107 ? HIS E 109 ? TYR C 107 HIS C 109 
AB3 2 ARG E 223 ? LEU E 225 ? ARG C 223 LEU C 225 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N CYS A 23  ? N CYS L 23  O TYR A 71  ? O TYR L 71  
AA1 2 3 O THR A 74  ? O THR L 74  N SER A 63  ? N SER L 63  
AA2 1 2 O LEU A 47  ? O LEU L 47  N TRP A 35  ? N TRP L 35  
AA2 2 3 N GLN A 38  ? N GLN L 38  O THR A 85  ? O THR L 85  
AA3 1 2 N GLN B 5   ? N GLN H 5   O LYS B 23  ? O LYS H 23  
AA3 2 3 N VAL B 18  ? N VAL H 18  O LEU B 83  ? O LEU H 83  
AA3 3 4 O TYR B 80  ? O TYR H 80  N THR B 71  ? N THR H 71  
AA4 1 7 N ALA B 12  ? N ALA H 12  O THR B 115 ? O THR H 115 
AA4 2 3 N LYS B 38  ? N LYS H 38  O GLU B 46  ? O GLU H 46  
AA4 2 5 N GLN B 39  ? N GLN H 39  O VAL B 93  ? O VAL H 93  
AA4 3 4 N TYR B 50  ? N TYR H 50  O GLU B 59  ? O GLU H 59  
AA4 5 6 N SER B 100 ? N SER H 100 O ARG B 104 ? O ARG H 104 
AA4 5 7 N TYR B 94  ? N TYR H 94  O THR B 112 ? O THR H 112 
AA5 1 6 N ALA C 77  ? N ALA A 77  O VAL C 233 ? O VAL A 233 
AA5 2 4 N LEU C 114 ? N LEU A 114 O ILE C 180 ? O ILE A 180 
AA5 2 5 N LEU C 110 ? N LEU A 110 O TYR C 189 ? O TYR A 189 
AA5 2 6 N ASP C 113 ? N ASP A 113 O LYS C 240 ? O LYS A 240 
AA5 3 6 N ALA C 123 ? N ALA A 123 O LYS C 230 ? O LYS A 230 
AA5 6 7 N ALA C 244 ? N ALA A 244 O VAL E 40  ? O VAL C 40  
AA6 1 2 N TRP C 90  ? N TRP A 90  O LEU C 216 ? O LEU A 216 
AA6 2 3 O THR C 215 ? O THR A 215 N VAL C 144 ? N VAL A 144 
AA6 3 4 N HIS C 139 ? N HIS A 139 O TRP C 169 ? O TRP A 169 
AA7 1 2 N ILE D 16  ? N ILE B 16  O ILE D 23  ? O ILE B 23  
AA8 1 5 N VAL D 32  ? N VAL B 32  O VAL D 203 ? O VAL B 203 
AA8 2 6 N TYR D 64  ? N TYR B 64  O ILE D 247 ? O ILE B 247 
AA8 3 6 N TRP D 71  ? N TRP B 71  O VAL D 241 ? O VAL B 241 
AA8 4 5 N ILE D 108 ? N ILE B 108 O LEU D 202 ? O LEU B 202 
AA8 4 6 N GLY D 105 ? N GLY B 105 O MET D 250 ? O MET B 250 
AA9 1 2 N TRP D 80  ? N TRP B 80  O LEU D 223 ? O LEU B 223 
AA9 2 3 O THR D 222 ? O THR B 222 N VAL D 127 ? N VAL B 127 
AA9 3 4 N LEU D 122 ? N LEU B 122 O ILE D 192 ? O ILE B 192 
AB1 1 5 N SER E 51  ? N SER C 51  O VAL E 214 ? O VAL C 214 
AB1 2 5 N ILE E 70  ? N ILE C 70  O ILE E 210 ? O ILE C 210 
AB1 3 4 N GLY E 112 ? N GLY C 112 O TRP E 170 ? O TRP C 170 
AB1 3 5 N THR E 117 ? N THR C 117 O PHE E 213 ? O PHE C 213 
AB2 1 2 N VAL E 82  ? N VAL C 82  O CYS E 192 ? O CYS C 192 
AB2 2 3 O TRP E 193 ? O TRP C 193 N LEU E 131 ? N LEU C 131 
AB2 3 4 N PHE E 130 ? N PHE C 130 O TRP E 156 ? O TRP C 156 
AB3 1 2 N HIS E 109 ? N HIS C 109 O ARG E 223 ? O ARG C 223 
# 
_atom_sites.entry_id                    7X38 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ASP A 1 1   ? 372.984 350.922 503.841 1.00 90.67  ? 1   ASP L N   1 
ATOM 2    C CA  . ASP A 1 1   ? 374.300 351.150 503.259 1.00 90.67  ? 1   ASP L CA  1 
ATOM 3    C C   . ASP A 1 1   ? 375.092 349.860 503.148 1.00 90.67  ? 1   ASP L C   1 
ATOM 4    O O   . ASP A 1 1   ? 374.596 348.780 503.461 1.00 90.67  ? 1   ASP L O   1 
ATOM 5    C CB  . ASP A 1 1   ? 375.088 352.161 504.090 1.00 90.67  ? 1   ASP L CB  1 
ATOM 6    C CG  . ASP A 1 1   ? 374.518 353.555 504.000 1.00 90.67  ? 1   ASP L CG  1 
ATOM 7    O OD1 . ASP A 1 1   ? 373.286 353.679 503.839 1.00 90.67  ? 1   ASP L OD1 1 
ATOM 8    O OD2 . ASP A 1 1   ? 375.299 354.526 504.085 1.00 90.67  ? 1   ASP L OD2 1 
ATOM 9    N N   . ILE A 1 2   ? 376.330 349.981 502.682 1.00 87.04  ? 2   ILE L N   1 
ATOM 10   C CA  . ILE A 1 2   ? 377.276 348.875 502.633 1.00 87.04  ? 2   ILE L CA  1 
ATOM 11   C C   . ILE A 1 2   ? 378.512 349.305 503.404 1.00 87.04  ? 2   ILE L C   1 
ATOM 12   O O   . ILE A 1 2   ? 379.119 350.332 503.085 1.00 87.04  ? 2   ILE L O   1 
ATOM 13   C CB  . ILE A 1 2   ? 377.644 348.487 501.193 1.00 87.04  ? 2   ILE L CB  1 
ATOM 14   C CG1 . ILE A 1 2   ? 376.384 348.248 500.355 1.00 87.04  ? 2   ILE L CG1 1 
ATOM 15   C CG2 . ILE A 1 2   ? 378.544 347.268 501.203 1.00 87.04  ? 2   ILE L CG2 1 
ATOM 16   C CD1 . ILE A 1 2   ? 376.625 347.574 499.022 1.00 87.04  ? 2   ILE L CD1 1 
ATOM 17   N N   . GLN A 1 3   ? 378.877 348.535 504.424 1.00 90.08  ? 3   GLN L N   1 
ATOM 18   C CA  . GLN A 1 3   ? 380.056 348.844 505.224 1.00 90.08  ? 3   GLN L CA  1 
ATOM 19   C C   . GLN A 1 3   ? 381.225 348.007 504.724 1.00 90.08  ? 3   GLN L C   1 
ATOM 20   O O   . GLN A 1 3   ? 381.243 346.786 504.899 1.00 90.08  ? 3   GLN L O   1 
ATOM 21   C CB  . GLN A 1 3   ? 379.784 348.580 506.700 1.00 90.08  ? 3   GLN L CB  1 
ATOM 22   C CG  . GLN A 1 3   ? 378.949 349.653 507.373 1.00 90.08  ? 3   GLN L CG  1 
ATOM 23   C CD  . GLN A 1 3   ? 377.463 349.429 507.198 1.00 90.08  ? 3   GLN L CD  1 
ATOM 24   O OE1 . GLN A 1 3   ? 376.934 348.385 507.576 1.00 90.08  ? 3   GLN L OE1 1 
ATOM 25   N NE2 . GLN A 1 3   ? 376.779 350.413 506.626 1.00 90.08  ? 3   GLN L NE2 1 
ATOM 26   N N   . MET A 1 4   ? 382.200 348.656 504.096 1.00 91.69  ? 4   MET L N   1 
ATOM 27   C CA  . MET A 1 4   ? 383.384 347.973 503.589 1.00 91.69  ? 4   MET L CA  1 
ATOM 28   C C   . MET A 1 4   ? 384.377 347.838 504.735 1.00 91.69  ? 4   MET L C   1 
ATOM 29   O O   . MET A 1 4   ? 384.703 348.825 505.402 1.00 91.69  ? 4   MET L O   1 
ATOM 30   C CB  . MET A 1 4   ? 383.992 348.739 502.420 1.00 91.69  ? 4   MET L CB  1 
ATOM 31   C CG  . MET A 1 4   ? 382.973 349.433 501.549 1.00 91.69  ? 4   MET L CG  1 
ATOM 32   S SD  . MET A 1 4   ? 382.034 348.284 500.545 1.00 91.69  ? 4   MET L SD  1 
ATOM 33   C CE  . MET A 1 4   ? 383.301 347.726 499.418 1.00 91.69  ? 4   MET L CE  1 
ATOM 34   N N   . THR A 1 5   ? 384.854 346.624 504.973 1.00 93.68  ? 5   THR L N   1 
ATOM 35   C CA  . THR A 1 5   ? 385.717 346.341 506.110 1.00 93.68  ? 5   THR L CA  1 
ATOM 36   C C   . THR A 1 5   ? 387.107 345.975 505.615 1.00 93.68  ? 5   THR L C   1 
ATOM 37   O O   . THR A 1 5   ? 387.309 344.890 505.063 1.00 93.68  ? 5   THR L O   1 
ATOM 38   C CB  . THR A 1 5   ? 385.143 345.214 506.968 1.00 93.68  ? 5   THR L CB  1 
ATOM 39   O OG1 . THR A 1 5   ? 385.049 344.017 506.188 1.00 93.68  ? 5   THR L OG1 1 
ATOM 40   C CG2 . THR A 1 5   ? 383.763 345.585 507.484 1.00 93.68  ? 5   THR L CG2 1 
ATOM 41   N N   . GLN A 1 6   ? 388.054 346.878 505.813 1.00 92.10  ? 6   GLN L N   1 
ATOM 42   C CA  . GLN A 1 6   ? 389.474 346.589 505.658 1.00 92.10  ? 6   GLN L CA  1 
ATOM 43   C C   . GLN A 1 6   ? 389.988 346.330 507.067 1.00 92.10  ? 6   GLN L C   1 
ATOM 44   O O   . GLN A 1 6   ? 390.307 347.267 507.803 1.00 92.10  ? 6   GLN L O   1 
ATOM 45   C CB  . GLN A 1 6   ? 390.206 347.739 504.981 1.00 92.10  ? 6   GLN L CB  1 
ATOM 46   C CG  . GLN A 1 6   ? 389.757 347.984 503.560 1.00 92.10  ? 6   GLN L CG  1 
ATOM 47   C CD  . GLN A 1 6   ? 390.735 348.825 502.782 1.00 92.10  ? 6   GLN L CD  1 
ATOM 48   O OE1 . GLN A 1 6   ? 390.385 349.425 501.772 1.00 92.10  ? 6   GLN L OE1 1 
ATOM 49   N NE2 . GLN A 1 6   ? 391.970 348.880 503.252 1.00 92.10  ? 6   GLN L NE2 1 
ATOM 50   N N   . THR A 1 7   ? 390.061 345.053 507.435 1.00 99.38  ? 7   THR L N   1 
ATOM 51   C CA  . THR A 1 7   ? 390.200 344.650 508.828 1.00 99.38  ? 7   THR L CA  1 
ATOM 52   C C   . THR A 1 7   ? 391.577 344.922 509.417 1.00 99.38  ? 7   THR L C   1 
ATOM 53   O O   . THR A 1 7   ? 391.697 345.011 510.642 1.00 99.38  ? 7   THR L O   1 
ATOM 54   C CB  . THR A 1 7   ? 389.883 343.158 508.968 1.00 99.38  ? 7   THR L CB  1 
ATOM 55   O OG1 . THR A 1 7   ? 390.495 342.439 507.891 1.00 99.38  ? 7   THR L OG1 1 
ATOM 56   C CG2 . THR A 1 7   ? 388.375 342.923 508.943 1.00 99.38  ? 7   THR L CG2 1 
ATOM 57   N N   . LYS A 1 8   ? 392.611 345.062 508.591 1.00 100.98 ? 8   LYS L N   1 
ATOM 58   C CA  . LYS A 1 8   ? 393.966 345.099 509.128 1.00 100.98 ? 8   LYS L CA  1 
ATOM 59   C C   . LYS A 1 8   ? 394.356 346.506 509.570 1.00 100.98 ? 8   LYS L C   1 
ATOM 60   O O   . LYS A 1 8   ? 394.782 346.711 510.711 1.00 100.98 ? 8   LYS L O   1 
ATOM 61   C CB  . LYS A 1 8   ? 394.951 344.568 508.086 1.00 100.98 ? 8   LYS L CB  1 
ATOM 62   C CG  . LYS A 1 8   ? 396.336 344.305 508.630 1.00 100.98 ? 8   LYS L CG  1 
ATOM 63   C CD  . LYS A 1 8   ? 396.301 343.184 509.648 1.00 100.98 ? 8   LYS L CD  1 
ATOM 64   C CE  . LYS A 1 8   ? 395.831 341.875 509.015 1.00 100.98 ? 8   LYS L CE  1 
ATOM 65   N NZ  . LYS A 1 8   ? 396.795 341.343 508.020 1.00 100.98 ? 8   LYS L NZ  1 
ATOM 66   N N   . SER A 1 9   ? 394.251 347.476 508.651 1.00 100.13 ? 9   SER L N   1 
ATOM 67   C CA  . SER A 1 9   ? 394.554 348.906 508.794 1.00 100.13 ? 9   SER L CA  1 
ATOM 68   C C   . SER A 1 9   ? 396.018 349.228 509.097 1.00 100.13 ? 9   SER L C   1 
ATOM 69   O O   . SER A 1 9   ? 396.355 350.395 509.318 1.00 100.13 ? 9   SER L O   1 
ATOM 70   C CB  . SER A 1 9   ? 393.664 349.573 509.855 1.00 100.13 ? 9   SER L CB  1 
ATOM 71   O OG  . SER A 1 9   ? 393.884 349.056 511.154 1.00 100.13 ? 9   SER L OG  1 
ATOM 72   N N   . SER A 1 10  ? 396.897 348.221 509.113 1.00 102.04 ? 10  SER L N   1 
ATOM 73   C CA  . SER A 1 10  ? 398.340 348.413 509.240 1.00 102.04 ? 10  SER L CA  1 
ATOM 74   C C   . SER A 1 10  ? 399.087 347.203 508.693 1.00 102.04 ? 10  SER L C   1 
ATOM 75   O O   . SER A 1 10  ? 399.074 346.137 509.314 1.00 102.04 ? 10  SER L O   1 
ATOM 76   C CB  . SER A 1 10  ? 398.763 348.639 510.697 1.00 102.04 ? 10  SER L CB  1 
ATOM 77   O OG  . SER A 1 10  ? 397.976 349.610 511.365 1.00 102.04 ? 10  SER L OG  1 
ATOM 78   N N   . LEU A 1 11  ? 399.744 347.350 507.548 1.00 103.77 ? 11  LEU L N   1 
ATOM 79   C CA  . LEU A 1 11  ? 400.583 346.300 506.988 1.00 103.77 ? 11  LEU L CA  1 
ATOM 80   C C   . LEU A 1 11  ? 402.047 346.623 507.227 1.00 103.77 ? 11  LEU L C   1 
ATOM 81   O O   . LEU A 1 11  ? 402.413 347.773 507.483 1.00 103.77 ? 11  LEU L O   1 
ATOM 82   C CB  . LEU A 1 11  ? 400.360 346.107 505.482 1.00 103.77 ? 11  LEU L CB  1 
ATOM 83   C CG  . LEU A 1 11  ? 399.403 345.029 504.967 1.00 103.77 ? 11  LEU L CG  1 
ATOM 84   C CD1 . LEU A 1 11  ? 399.912 343.658 505.355 1.00 103.77 ? 11  LEU L CD1 1 
ATOM 85   C CD2 . LEU A 1 11  ? 397.999 345.229 505.467 1.00 103.77 ? 11  LEU L CD2 1 
ATOM 86   N N   . SER A 1 12  ? 402.883 345.593 507.143 1.00 109.66 ? 12  SER L N   1 
ATOM 87   C CA  . SER A 1 12  ? 404.325 345.746 507.273 1.00 109.66 ? 12  SER L CA  1 
ATOM 88   C C   . SER A 1 12  ? 405.021 344.678 506.446 1.00 109.66 ? 12  SER L C   1 
ATOM 89   O O   . SER A 1 12  ? 404.743 343.486 506.610 1.00 109.66 ? 12  SER L O   1 
ATOM 90   C CB  . SER A 1 12  ? 404.760 345.664 508.736 1.00 109.66 ? 12  SER L CB  1 
ATOM 91   O OG  . SER A 1 12  ? 404.601 346.918 509.373 1.00 109.66 ? 12  SER L OG  1 
ATOM 92   N N   . ALA A 1 13  ? 405.923 345.107 505.565 1.00 110.84 ? 13  ALA L N   1 
ATOM 93   C CA  . ALA A 1 13  ? 406.727 344.185 504.776 1.00 110.84 ? 13  ALA L CA  1 
ATOM 94   C C   . ALA A 1 13  ? 408.041 344.850 504.396 1.00 110.84 ? 13  ALA L C   1 
ATOM 95   O O   . ALA A 1 13  ? 408.247 346.040 504.644 1.00 110.84 ? 13  ALA L O   1 
ATOM 96   C CB  . ALA A 1 13  ? 405.994 343.727 503.518 1.00 110.84 ? 13  ALA L CB  1 
ATOM 97   N N   . SER A 1 14  ? 408.935 344.062 503.808 1.00 110.35 ? 14  SER L N   1 
ATOM 98   C CA  . SER A 1 14  ? 410.196 344.580 503.297 1.00 110.35 ? 14  SER L CA  1 
ATOM 99   C C   . SER A 1 14  ? 410.013 345.025 501.847 1.00 110.35 ? 14  SER L C   1 
ATOM 100  O O   . SER A 1 14  ? 408.894 345.155 501.345 1.00 110.35 ? 14  SER L O   1 
ATOM 101  C CB  . SER A 1 14  ? 411.295 343.531 503.437 1.00 110.35 ? 14  SER L CB  1 
ATOM 102  O OG  . SER A 1 14  ? 412.499 343.967 502.830 1.00 110.35 ? 14  SER L OG  1 
ATOM 103  N N   . LEU A 1 15  ? 411.120 345.275 501.155 1.00 107.94 ? 15  LEU L N   1 
ATOM 104  C CA  . LEU A 1 15  ? 411.063 345.627 499.745 1.00 107.94 ? 15  LEU L CA  1 
ATOM 105  C C   . LEU A 1 15  ? 411.331 344.405 498.879 1.00 107.94 ? 15  LEU L C   1 
ATOM 106  O O   . LEU A 1 15  ? 412.253 343.630 499.142 1.00 107.94 ? 15  LEU L O   1 
ATOM 107  C CB  . LEU A 1 15  ? 412.074 346.727 499.422 1.00 107.94 ? 15  LEU L CB  1 
ATOM 108  C CG  . LEU A 1 15  ? 411.750 348.125 499.955 1.00 107.94 ? 15  LEU L CG  1 
ATOM 109  C CD1 . LEU A 1 15  ? 412.490 348.395 501.253 1.00 107.94 ? 15  LEU L CD1 1 
ATOM 110  C CD2 . LEU A 1 15  ? 412.070 349.194 498.920 1.00 107.94 ? 15  LEU L CD2 1 
ATOM 111  N N   . GLY A 1 16  ? 410.513 344.235 497.843 1.00 103.66 ? 16  GLY L N   1 
ATOM 112  C CA  . GLY A 1 16  ? 410.703 343.160 496.892 1.00 103.66 ? 16  GLY L CA  1 
ATOM 113  C C   . GLY A 1 16  ? 409.737 342.005 497.006 1.00 103.66 ? 16  GLY L C   1 
ATOM 114  O O   . GLY A 1 16  ? 409.759 341.118 496.147 1.00 103.66 ? 16  GLY L O   1 
ATOM 115  N N   . ASP A 1 17  ? 408.883 341.987 498.022 1.00 104.36 ? 17  ASP L N   1 
ATOM 116  C CA  . ASP A 1 17  ? 407.995 340.862 498.263 1.00 104.36 ? 17  ASP L CA  1 
ATOM 117  C C   . ASP A 1 17  ? 406.564 341.198 497.843 1.00 104.36 ? 17  ASP L C   1 
ATOM 118  O O   . ASP A 1 17  ? 406.268 342.290 497.357 1.00 104.36 ? 17  ASP L O   1 
ATOM 119  C CB  . ASP A 1 17  ? 408.079 340.430 499.731 1.00 104.36 ? 17  ASP L CB  1 
ATOM 120  C CG  . ASP A 1 17  ? 407.851 341.575 500.698 1.00 104.36 ? 17  ASP L CG  1 
ATOM 121  O OD1 . ASP A 1 17  ? 407.725 342.730 500.245 1.00 104.36 ? 17  ASP L OD1 1 
ATOM 122  O OD2 . ASP A 1 17  ? 407.807 341.319 501.918 1.00 104.36 ? 17  ASP L OD2 1 
ATOM 123  N N   . ARG A 1 18  ? 405.667 340.239 498.045 1.00 98.44  ? 18  ARG L N   1 
ATOM 124  C CA  . ARG A 1 18  ? 404.305 340.305 497.533 1.00 98.44  ? 18  ARG L CA  1 
ATOM 125  C C   . ARG A 1 18  ? 403.345 340.617 498.673 1.00 98.44  ? 18  ARG L C   1 
ATOM 126  O O   . ARG A 1 18  ? 403.236 339.841 499.627 1.00 98.44  ? 18  ARG L O   1 
ATOM 127  C CB  . ARG A 1 18  ? 403.934 338.987 496.854 1.00 98.44  ? 18  ARG L CB  1 
ATOM 128  C CG  . ARG A 1 18  ? 402.476 338.852 496.460 1.00 98.44  ? 18  ARG L CG  1 
ATOM 129  C CD  . ARG A 1 18  ? 402.278 337.645 495.559 1.00 98.44  ? 18  ARG L CD  1 
ATOM 130  N NE  . ARG A 1 18  ? 403.183 337.665 494.415 1.00 98.44  ? 18  ARG L NE  1 
ATOM 131  C CZ  . ARG A 1 18  ? 402.827 338.029 493.188 1.00 98.44  ? 18  ARG L CZ  1 
ATOM 132  N NH1 . ARG A 1 18  ? 401.580 338.391 492.937 1.00 98.44  ? 18  ARG L NH1 1 
ATOM 133  N NH2 . ARG A 1 18  ? 403.717 338.020 492.206 1.00 98.44  ? 18  ARG L NH2 1 
ATOM 134  N N   . VAL A 1 19  ? 402.643 341.742 498.565 1.00 93.52  ? 19  VAL L N   1 
ATOM 135  C CA  . VAL A 1 19  ? 401.734 342.209 499.603 1.00 93.52  ? 19  VAL L CA  1 
ATOM 136  C C   . VAL A 1 19  ? 400.310 342.209 499.072 1.00 93.52  ? 19  VAL L C   1 
ATOM 137  O O   . VAL A 1 19  ? 400.056 342.510 497.901 1.00 93.52  ? 19  VAL L O   1 
ATOM 138  C CB  . VAL A 1 19  ? 402.125 343.609 500.115 1.00 93.52  ? 19  VAL L CB  1 
ATOM 139  C CG1 . VAL A 1 19  ? 403.292 343.502 501.041 1.00 93.52  ? 19  VAL L CG1 1 
ATOM 140  C CG2 . VAL A 1 19  ? 402.486 344.507 498.962 1.00 93.52  ? 19  VAL L CG2 1 
ATOM 141  N N   . THR A 1 20  ? 399.373 341.861 499.951 1.00 89.20  ? 20  THR L N   1 
ATOM 142  C CA  . THR A 1 20  ? 397.960 341.777 499.601 1.00 89.20  ? 20  THR L CA  1 
ATOM 143  C C   . THR A 1 20  ? 397.146 342.532 500.638 1.00 89.20  ? 20  THR L C   1 
ATOM 144  O O   . THR A 1 20  ? 397.214 342.217 501.828 1.00 89.20  ? 20  THR L O   1 
ATOM 145  C CB  . THR A 1 20  ? 397.497 340.320 499.517 1.00 89.20  ? 20  THR L CB  1 
ATOM 146  O OG1 . THR A 1 20  ? 398.056 339.703 498.351 1.00 89.20  ? 20  THR L OG1 1 
ATOM 147  C CG2 . THR A 1 20  ? 395.985 340.236 499.443 1.00 89.20  ? 20  THR L CG2 1 
ATOM 148  N N   . ILE A 1 21  ? 396.388 343.527 500.191 1.00 86.16  ? 21  ILE L N   1 
ATOM 149  C CA  . ILE A 1 21  ? 395.417 344.218 501.028 1.00 86.16  ? 21  ILE L CA  1 
ATOM 150  C C   . ILE A 1 21  ? 394.035 343.752 500.604 1.00 86.16  ? 21  ILE L C   1 
ATOM 151  O O   . ILE A 1 21  ? 393.744 343.671 499.405 1.00 86.16  ? 21  ILE L O   1 
ATOM 152  C CB  . ILE A 1 21  ? 395.544 345.746 500.917 1.00 86.16  ? 21  ILE L CB  1 
ATOM 153  C CG1 . ILE A 1 21  ? 397.017 346.155 500.916 1.00 86.16  ? 21  ILE L CG1 1 
ATOM 154  C CG2 . ILE A 1 21  ? 394.792 346.418 502.055 1.00 86.16  ? 21  ILE L CG2 1 
ATOM 155  C CD1 . ILE A 1 21  ? 397.247 347.645 501.010 1.00 86.16  ? 21  ILE L CD1 1 
ATOM 156  N N   . SER A 1 22  ? 393.190 343.441 501.580 1.00 86.81  ? 22  SER L N   1 
ATOM 157  C CA  . SER A 1 22  ? 391.886 342.850 501.329 1.00 86.81  ? 22  SER L CA  1 
ATOM 158  C C   . SER A 1 22  ? 390.778 343.800 501.756 1.00 86.81  ? 22  SER L C   1 
ATOM 159  O O   . SER A 1 22  ? 390.887 344.479 502.779 1.00 86.81  ? 22  SER L O   1 
ATOM 160  C CB  . SER A 1 22  ? 391.742 341.519 502.066 1.00 86.81  ? 22  SER L CB  1 
ATOM 161  O OG  . SER A 1 22  ? 392.393 340.475 501.364 1.00 86.81  ? 22  SER L OG  1 
ATOM 162  N N   . CYS A 1 23  ? 389.712 343.834 500.965 1.00 89.49  ? 23  CYS L N   1 
ATOM 163  C CA  . CYS A 1 23  ? 388.531 344.638 501.253 1.00 89.49  ? 23  CYS L CA  1 
ATOM 164  C C   . CYS A 1 23  ? 387.338 343.700 501.234 1.00 89.49  ? 23  CYS L C   1 
ATOM 165  O O   . CYS A 1 23  ? 387.144 342.969 500.259 1.00 89.49  ? 23  CYS L O   1 
ATOM 166  C CB  . CYS A 1 23  ? 388.370 345.765 500.224 1.00 89.49  ? 23  CYS L CB  1 
ATOM 167  S SG  . CYS A 1 23  ? 386.845 346.738 500.312 1.00 89.49  ? 23  CYS L SG  1 
ATOM 168  N N   . ARG A 1 24  ? 386.562 343.693 502.312 1.00 91.54  ? 24  ARG L N   1 
ATOM 169  C CA  . ARG A 1 24  ? 385.438 342.782 502.463 1.00 91.54  ? 24  ARG L CA  1 
ATOM 170  C C   . ARG A 1 24  ? 384.159 343.587 502.620 1.00 91.54  ? 24  ARG L C   1 
ATOM 171  O O   . ARG A 1 24  ? 384.060 344.429 503.517 1.00 91.54  ? 24  ARG L O   1 
ATOM 172  C CB  . ARG A 1 24  ? 385.637 341.863 503.665 1.00 91.54  ? 24  ARG L CB  1 
ATOM 173  C CG  . ARG A 1 24  ? 384.581 340.790 503.792 1.00 91.54  ? 24  ARG L CG  1 
ATOM 174  C CD  . ARG A 1 24  ? 384.563 340.177 505.182 1.00 91.54  ? 24  ARG L CD  1 
ATOM 175  N NE  . ARG A 1 24  ? 383.311 339.471 505.438 1.00 91.54  ? 24  ARG L NE  1 
ATOM 176  C CZ  . ARG A 1 24  ? 382.196 340.056 505.865 1.00 91.54  ? 24  ARG L CZ  1 
ATOM 177  N NH1 . ARG A 1 24  ? 382.171 341.360 506.092 1.00 91.54  ? 24  ARG L NH1 1 
ATOM 178  N NH2 . ARG A 1 24  ? 381.103 339.336 506.068 1.00 91.54  ? 24  ARG L NH2 1 
ATOM 179  N N   . ALA A 1 25  ? 383.184 343.320 501.762 1.00 89.47  ? 25  ALA L N   1 
ATOM 180  C CA  . ALA A 1 25  ? 381.975 344.126 501.700 1.00 89.47  ? 25  ALA L CA  1 
ATOM 181  C C   . ALA A 1 25  ? 380.947 343.627 502.714 1.00 89.47  ? 25  ALA L C   1 
ATOM 182  O O   . ALA A 1 25  ? 381.223 342.755 503.541 1.00 89.47  ? 25  ALA L O   1 
ATOM 183  C CB  . ALA A 1 25  ? 381.417 344.117 500.280 1.00 89.47  ? 25  ALA L CB  1 
ATOM 184  N N   . SER A 1 26  ? 379.742 344.192 502.660 1.00 89.69  ? 26  SER L N   1 
ATOM 185  C CA  . SER A 1 26  ? 378.635 343.757 503.501 1.00 89.69  ? 26  SER L CA  1 
ATOM 186  C C   . SER A 1 26  ? 377.641 342.907 502.720 1.00 89.69  ? 26  SER L C   1 
ATOM 187  O O   . SER A 1 26  ? 376.880 342.138 503.312 1.00 89.69  ? 26  SER L O   1 
ATOM 188  C CB  . SER A 1 26  ? 377.929 344.967 504.118 1.00 89.69  ? 26  SER L CB  1 
ATOM 189  O OG  . SER A 1 26  ? 378.831 345.762 504.864 1.00 89.69  ? 26  SER L OG  1 
ATOM 190  N N   . GLN A 1 27  ? 377.622 343.052 501.398 1.00 89.84  ? 27  GLN L N   1 
ATOM 191  C CA  . GLN A 1 27  ? 376.820 342.193 500.538 1.00 89.84  ? 27  GLN L CA  1 
ATOM 192  C C   . GLN A 1 27  ? 377.466 342.090 499.167 1.00 89.84  ? 27  GLN L C   1 
ATOM 193  O O   . GLN A 1 27  ? 378.588 342.563 498.972 1.00 89.84  ? 27  GLN L O   1 
ATOM 194  C CB  . GLN A 1 27  ? 375.389 342.713 500.428 1.00 89.84  ? 27  GLN L CB  1 
ATOM 195  C CG  . GLN A 1 27  ? 375.278 344.198 500.191 1.00 89.84  ? 27  GLN L CG  1 
ATOM 196  C CD  . GLN A 1 27  ? 373.921 344.738 500.592 1.00 89.84  ? 27  GLN L CD  1 
ATOM 197  O OE1 . GLN A 1 27  ? 372.990 343.975 500.842 1.00 89.84  ? 27  GLN L OE1 1 
ATOM 198  N NE2 . GLN A 1 27  ? 373.804 346.057 500.664 1.00 89.84  ? 27  GLN L NE2 1 
ATOM 199  N N   . ASP A 1 28  ? 376.780 341.462 498.221 1.00 87.57  ? 28  ASP L N   1 
ATOM 200  C CA  . ASP A 1 28  ? 377.305 341.327 496.870 1.00 87.57  ? 28  ASP L CA  1 
ATOM 201  C C   . ASP A 1 28  ? 377.257 342.694 496.202 1.00 87.57  ? 28  ASP L C   1 
ATOM 202  O O   . ASP A 1 28  ? 376.202 343.333 496.162 1.00 87.57  ? 28  ASP L O   1 
ATOM 203  C CB  . ASP A 1 28  ? 376.479 340.286 496.109 1.00 87.57  ? 28  ASP L CB  1 
ATOM 204  C CG  . ASP A 1 28  ? 377.029 339.943 494.718 1.00 87.57  ? 28  ASP L CG  1 
ATOM 205  O OD1 . ASP A 1 28  ? 377.331 340.827 493.890 1.00 87.57  ? 28  ASP L OD1 1 
ATOM 206  O OD2 . ASP A 1 28  ? 377.163 338.732 494.451 1.00 87.57  ? 28  ASP L OD2 1 
ATOM 207  N N   . ILE A 1 29  ? 378.400 343.152 495.688 1.00 82.45  ? 29  ILE L N   1 
ATOM 208  C CA  . ILE A 1 29  ? 378.463 344.442 495.013 1.00 82.45  ? 29  ILE L CA  1 
ATOM 209  C C   . ILE A 1 29  ? 378.746 344.310 493.527 1.00 82.45  ? 29  ILE L C   1 
ATOM 210  O O   . ILE A 1 29  ? 378.831 345.333 492.837 1.00 82.45  ? 29  ILE L O   1 
ATOM 211  C CB  . ILE A 1 29  ? 379.496 345.374 495.672 1.00 82.45  ? 29  ILE L CB  1 
ATOM 212  C CG1 . ILE A 1 29  ? 380.914 344.897 495.396 1.00 82.45  ? 29  ILE L CG1 1 
ATOM 213  C CG2 . ILE A 1 29  ? 379.255 345.462 497.163 1.00 82.45  ? 29  ILE L CG2 1 
ATOM 214  C CD1 . ILE A 1 29  ? 381.953 345.781 496.020 1.00 82.45  ? 29  ILE L CD1 1 
ATOM 215  N N   . SER A 1 30  ? 378.922 343.083 493.026 1.00 80.13  ? 30  SER L N   1 
ATOM 216  C CA  . SER A 1 30  ? 378.870 342.737 491.602 1.00 80.13  ? 30  SER L CA  1 
ATOM 217  C C   . SER A 1 30  ? 379.949 343.445 490.783 1.00 80.13  ? 30  SER L C   1 
ATOM 218  O O   . SER A 1 30  ? 379.664 344.140 489.807 1.00 80.13  ? 30  SER L O   1 
ATOM 219  C CB  . SER A 1 30  ? 377.482 343.016 491.020 1.00 80.13  ? 30  SER L CB  1 
ATOM 220  O OG  . SER A 1 30  ? 377.531 343.010 489.604 1.00 80.13  ? 30  SER L OG  1 
ATOM 221  N N   . ASN A 1 31  ? 381.193 343.267 491.224 1.00 77.66  ? 31  ASN L N   1 
ATOM 222  C CA  . ASN A 1 31  ? 382.410 343.646 490.506 1.00 77.66  ? 31  ASN L CA  1 
ATOM 223  C C   . ASN A 1 31  ? 382.535 345.147 490.260 1.00 77.66  ? 31  ASN L C   1 
ATOM 224  O O   . ASN A 1 31  ? 383.221 345.563 489.325 1.00 77.66  ? 31  ASN L O   1 
ATOM 225  C CB  . ASN A 1 31  ? 382.535 342.892 489.177 1.00 77.66  ? 31  ASN L CB  1 
ATOM 226  C CG  . ASN A 1 31  ? 383.105 341.504 489.345 1.00 77.66  ? 31  ASN L CG  1 
ATOM 227  O OD1 . ASN A 1 31  ? 382.624 340.719 490.158 1.00 77.66  ? 31  ASN L OD1 1 
ATOM 228  N ND2 . ASN A 1 31  ? 384.123 341.185 488.559 1.00 77.66  ? 31  ASN L ND2 1 
ATOM 229  N N   . TYR A 1 32  ? 381.900 345.980 491.079 1.00 74.98  ? 32  TYR L N   1 
ATOM 230  C CA  . TYR A 1 32  ? 382.035 347.433 490.977 0.88 74.98  ? 32  TYR L CA  1 
ATOM 231  C C   . TYR A 1 32  ? 382.840 347.901 492.178 1.00 74.98  ? 32  TYR L C   1 
ATOM 232  O O   . TYR A 1 32  ? 382.287 348.310 493.196 1.00 74.98  ? 32  TYR L O   1 
ATOM 233  C CB  . TYR A 1 32  ? 380.675 348.117 490.930 0.88 74.98  ? 32  TYR L CB  1 
ATOM 234  C CG  . TYR A 1 32  ? 379.941 347.935 489.632 1.00 74.98  ? 32  TYR L CG  1 
ATOM 235  C CD1 . TYR A 1 32  ? 380.542 348.249 488.426 1.00 74.98  ? 32  TYR L CD1 1 
ATOM 236  C CD2 . TYR A 1 32  ? 378.646 347.453 489.615 1.00 74.98  ? 32  TYR L CD2 1 
ATOM 237  C CE1 . TYR A 1 32  ? 379.872 348.081 487.235 1.00 74.98  ? 32  TYR L CE1 1 
ATOM 238  C CE2 . TYR A 1 32  ? 377.967 347.284 488.433 1.00 74.98  ? 32  TYR L CE2 1 
ATOM 239  C CZ  . TYR A 1 32  ? 378.585 347.598 487.246 1.00 74.98  ? 32  TYR L CZ  1 
ATOM 240  O OH  . TYR A 1 32  ? 377.906 347.427 486.066 1.00 74.98  ? 32  TYR L OH  1 
ATOM 241  N N   . LEU A 1 33  ? 384.159 347.854 492.054 1.00 74.59  ? 33  LEU L N   1 
ATOM 242  C CA  . LEU A 1 33  ? 385.042 348.254 493.135 1.00 74.59  ? 33  LEU L CA  1 
ATOM 243  C C   . LEU A 1 33  ? 386.138 349.141 492.569 1.00 74.59  ? 33  LEU L C   1 
ATOM 244  O O   . LEU A 1 33  ? 386.530 348.996 491.413 1.00 74.59  ? 33  LEU L O   1 
ATOM 245  C CB  . LEU A 1 33  ? 385.641 347.035 493.831 1.00 74.59  ? 33  LEU L CB  1 
ATOM 246  C CG  . LEU A 1 33  ? 386.369 347.261 495.147 1.00 74.59  ? 33  LEU L CG  1 
ATOM 247  C CD1 . LEU A 1 33  ? 385.410 347.199 496.302 1.00 74.59  ? 33  LEU L CD1 1 
ATOM 248  C CD2 . LEU A 1 33  ? 387.456 346.237 495.293 1.00 74.59  ? 33  LEU L CD2 1 
ATOM 249  N N   . ASN A 1 34  ? 386.611 350.083 493.379 1.00 74.42  ? 34  ASN L N   1 
ATOM 250  C CA  . ASN A 1 34  ? 387.705 350.954 492.989 1.00 74.42  ? 34  ASN L CA  1 
ATOM 251  C C   . ASN A 1 34  ? 388.721 351.019 494.117 1.00 74.42  ? 34  ASN L C   1 
ATOM 252  O O   . ASN A 1 34  ? 388.363 350.976 495.294 1.00 74.42  ? 34  ASN L O   1 
ATOM 253  C CB  . ASN A 1 34  ? 387.209 352.356 492.642 1.00 74.42  ? 34  ASN L CB  1 
ATOM 254  C CG  . ASN A 1 34  ? 386.089 352.343 491.620 1.00 74.42  ? 34  ASN L CG  1 
ATOM 255  O OD1 . ASN A 1 34  ? 386.216 351.755 490.552 1.00 74.42  ? 34  ASN L OD1 1 
ATOM 256  N ND2 . ASN A 1 34  ? 384.983 352.993 491.947 1.00 74.42  ? 34  ASN L ND2 1 
ATOM 257  N N   . TRP A 1 35  ? 389.994 351.122 493.746 1.00 76.20  ? 35  TRP L N   1 
ATOM 258  C CA  . TRP A 1 35  ? 391.101 351.135 494.695 1.00 76.20  ? 35  TRP L CA  1 
ATOM 259  C C   . TRP A 1 35  ? 391.837 352.460 494.582 1.00 76.20  ? 35  TRP L C   1 
ATOM 260  O O   . TRP A 1 35  ? 392.359 352.790 493.513 1.00 76.20  ? 35  TRP L O   1 
ATOM 261  C CB  . TRP A 1 35  ? 392.065 349.981 494.428 1.00 76.20  ? 35  TRP L CB  1 
ATOM 262  C CG  . TRP A 1 35  ? 391.632 348.679 494.992 1.00 76.20  ? 35  TRP L CG  1 
ATOM 263  C CD1 . TRP A 1 35  ? 391.138 347.614 494.305 1.00 76.20  ? 35  TRP L CD1 1 
ATOM 264  C CD2 . TRP A 1 35  ? 391.662 348.292 496.363 1.00 76.20  ? 35  TRP L CD2 1 
ATOM 265  N NE1 . TRP A 1 35  ? 390.856 346.588 495.165 1.00 76.20  ? 35  TRP L NE1 1 
ATOM 266  C CE2 . TRP A 1 35  ? 391.167 346.983 496.438 1.00 76.20  ? 35  TRP L CE2 1 
ATOM 267  C CE3 . TRP A 1 35  ? 392.057 348.929 497.538 1.00 76.20  ? 35  TRP L CE3 1 
ATOM 268  C CZ2 . TRP A 1 35  ? 391.058 346.300 497.637 1.00 76.20  ? 35  TRP L CZ2 1 
ATOM 269  C CZ3 . TRP A 1 35  ? 391.949 348.250 498.723 1.00 76.20  ? 35  TRP L CZ3 1 
ATOM 270  C CH2 . TRP A 1 35  ? 391.455 346.950 498.766 1.00 76.20  ? 35  TRP L CH2 1 
ATOM 271  N N   . TYR A 1 36  ? 391.892 353.209 495.676 1.00 76.32  ? 36  TYR L N   1 
ATOM 272  C CA  . TYR A 1 36  ? 392.555 354.501 495.697 1.00 76.32  ? 36  TYR L CA  1 
ATOM 273  C C   . TYR A 1 36  ? 393.790 354.451 496.583 1.00 76.32  ? 36  TYR L C   1 
ATOM 274  O O   . TYR A 1 36  ? 393.925 353.584 497.448 1.00 76.32  ? 36  TYR L O   1 
ATOM 275  C CB  . TYR A 1 36  ? 391.612 355.600 496.193 1.00 76.32  ? 36  TYR L CB  1 
ATOM 276  C CG  . TYR A 1 36  ? 390.357 355.747 495.381 1.00 76.32  ? 36  TYR L CG  1 
ATOM 277  C CD1 . TYR A 1 36  ? 390.336 356.517 494.234 1.00 76.32  ? 36  TYR L CD1 1 
ATOM 278  C CD2 . TYR A 1 36  ? 389.190 355.122 495.770 1.00 76.32  ? 36  TYR L CD2 1 
ATOM 279  C CE1 . TYR A 1 36  ? 389.189 356.652 493.496 1.00 76.32  ? 36  TYR L CE1 1 
ATOM 280  C CE2 . TYR A 1 36  ? 388.042 355.249 495.040 1.00 76.32  ? 36  TYR L CE2 1 
ATOM 281  C CZ  . TYR A 1 36  ? 388.045 356.011 493.904 1.00 76.32  ? 36  TYR L CZ  1 
ATOM 282  O OH  . TYR A 1 36  ? 386.887 356.132 493.182 1.00 76.32  ? 36  TYR L OH  1 
ATOM 283  N N   . GLN A 1 37  ? 394.687 355.409 496.368 1.00 80.23  ? 37  GLN L N   1 
ATOM 284  C CA  . GLN A 1 37  ? 395.947 355.481 497.096 1.00 80.23  ? 37  GLN L CA  1 
ATOM 285  C C   . GLN A 1 37  ? 396.189 356.912 497.540 1.00 80.23  ? 37  GLN L C   1 
ATOM 286  O O   . GLN A 1 37  ? 396.331 357.804 496.700 1.00 80.23  ? 37  GLN L O   1 
ATOM 287  C CB  . GLN A 1 37  ? 397.111 355.003 496.234 1.00 80.23  ? 37  GLN L CB  1 
ATOM 288  C CG  . GLN A 1 37  ? 398.430 355.026 496.962 1.00 80.23  ? 37  GLN L CG  1 
ATOM 289  C CD  . GLN A 1 37  ? 399.595 355.253 496.039 1.00 80.23  ? 37  GLN L CD  1 
ATOM 290  O OE1 . GLN A 1 37  ? 399.529 356.085 495.136 1.00 80.23  ? 37  GLN L OE1 1 
ATOM 291  N NE2 . GLN A 1 37  ? 400.676 354.515 496.257 1.00 80.23  ? 37  GLN L NE2 1 
ATOM 292  N N   . GLN A 1 38  ? 396.265 357.127 498.847 1.00 83.09  ? 38  GLN L N   1 
ATOM 293  C CA  . GLN A 1 38  ? 396.491 358.452 499.408 1.00 83.09  ? 38  GLN L CA  1 
ATOM 294  C C   . GLN A 1 38  ? 397.919 358.528 499.923 1.00 83.09  ? 38  GLN L C   1 
ATOM 295  O O   . GLN A 1 38  ? 398.275 357.838 500.882 1.00 83.09  ? 38  GLN L O   1 
ATOM 296  C CB  . GLN A 1 38  ? 395.500 358.750 500.526 1.00 83.09  ? 38  GLN L CB  1 
ATOM 297  C CG  . GLN A 1 38  ? 395.833 359.987 501.334 1.00 83.09  ? 38  GLN L CG  1 
ATOM 298  C CD  . GLN A 1 38  ? 394.661 360.468 502.150 1.00 83.09  ? 38  GLN L CD  1 
ATOM 299  O OE1 . GLN A 1 38  ? 393.666 359.767 502.289 1.00 83.09  ? 38  GLN L OE1 1 
ATOM 300  N NE2 . GLN A 1 38  ? 394.771 361.671 502.696 1.00 83.09  ? 38  GLN L NE2 1 
ATOM 301  N N   . LYS A 1 39  ? 398.730 359.367 499.288 1.00 86.04  ? 39  LYS L N   1 
ATOM 302  C CA  . LYS A 1 39  ? 400.090 359.598 499.739 1.00 86.04  ? 39  LYS L CA  1 
ATOM 303  C C   . LYS A 1 39  ? 400.074 360.365 501.064 1.00 86.04  ? 39  LYS L C   1 
ATOM 304  O O   . LYS A 1 39  ? 399.081 361.020 501.388 1.00 86.04  ? 39  LYS L O   1 
ATOM 305  C CB  . LYS A 1 39  ? 400.859 360.375 498.675 1.00 86.04  ? 39  LYS L CB  1 
ATOM 306  C CG  . LYS A 1 39  ? 401.079 359.610 497.391 1.00 86.04  ? 39  LYS L CG  1 
ATOM 307  C CD  . LYS A 1 39  ? 402.073 358.488 497.585 1.00 86.04  ? 39  LYS L CD  1 
ATOM 308  C CE  . LYS A 1 39  ? 403.453 359.028 497.875 1.00 86.04  ? 39  LYS L CE  1 
ATOM 309  N NZ  . LYS A 1 39  ? 404.390 357.942 498.257 1.00 86.04  ? 39  LYS L NZ  1 
ATOM 310  N N   . PRO A 1 40  ? 401.143 360.267 501.868 1.00 89.15  ? 40  PRO L N   1 
ATOM 311  C CA  . PRO A 1 40  ? 401.156 360.968 503.165 1.00 89.15  ? 40  PRO L CA  1 
ATOM 312  C C   . PRO A 1 40  ? 401.138 362.486 503.075 1.00 89.15  ? 40  PRO L C   1 
ATOM 313  O O   . PRO A 1 40  ? 400.673 363.127 504.026 1.00 89.15  ? 40  PRO L O   1 
ATOM 314  C CB  . PRO A 1 40  ? 402.455 360.481 503.813 1.00 89.15  ? 40  PRO L CB  1 
ATOM 315  C CG  . PRO A 1 40  ? 402.701 359.167 503.200 1.00 89.15  ? 40  PRO L CG  1 
ATOM 316  C CD  . PRO A 1 40  ? 402.254 359.300 501.783 1.00 89.15  ? 40  PRO L CD  1 
ATOM 317  N N   . ASP A 1 41  ? 401.608 363.087 501.981 1.00 89.10  ? 41  ASP L N   1 
ATOM 318  C CA  . ASP A 1 41  ? 401.522 364.537 501.866 1.00 89.10  ? 41  ASP L CA  1 
ATOM 319  C C   . ASP A 1 41  ? 400.134 365.018 501.469 1.00 89.10  ? 41  ASP L C   1 
ATOM 320  O O   . ASP A 1 41  ? 399.899 366.230 501.464 1.00 89.10  ? 41  ASP L O   1 
ATOM 321  C CB  . ASP A 1 41  ? 402.560 365.065 500.871 1.00 89.10  ? 41  ASP L CB  1 
ATOM 322  C CG  . ASP A 1 41  ? 402.505 364.364 499.530 1.00 89.10  ? 41  ASP L CG  1 
ATOM 323  O OD1 . ASP A 1 41  ? 401.712 363.419 499.375 1.00 89.10  ? 41  ASP L OD1 1 
ATOM 324  O OD2 . ASP A 1 41  ? 403.268 364.756 498.624 1.00 89.10  ? 41  ASP L OD2 1 
ATOM 325  N N   . GLY A 1 42  ? 399.223 364.111 501.125 1.00 84.62  ? 42  GLY L N   1 
ATOM 326  C CA  . GLY A 1 42  ? 397.828 364.453 500.907 1.00 84.62  ? 42  GLY L CA  1 
ATOM 327  C C   . GLY A 1 42  ? 397.266 364.094 499.548 1.00 84.62  ? 42  GLY L C   1 
ATOM 328  O O   . GLY A 1 42  ? 396.039 364.001 499.421 1.00 84.62  ? 42  GLY L O   1 
ATOM 329  N N   . SER A 1 43  ? 398.083 363.875 498.523 1.00 81.29  ? 43  SER L N   1 
ATOM 330  C CA  . SER A 1 43  ? 397.574 363.709 497.169 1.00 81.29  ? 43  SER L CA  1 
ATOM 331  C C   . SER A 1 43  ? 396.955 362.329 496.979 1.00 81.29  ? 43  SER L C   1 
ATOM 332  O O   . SER A 1 43  ? 397.608 361.307 497.202 1.00 81.29  ? 43  SER L O   1 
ATOM 333  C CB  . SER A 1 43  ? 398.696 363.926 496.157 1.00 81.29  ? 43  SER L CB  1 
ATOM 334  O OG  . SER A 1 43  ? 399.363 362.711 495.877 1.00 81.29  ? 43  SER L OG  1 
ATOM 335  N N   . VAL A 1 44  ? 395.698 362.307 496.546 1.00 74.80  ? 44  VAL L N   1 
ATOM 336  C CA  . VAL A 1 44  ? 394.934 361.083 496.360 1.00 74.80  ? 44  VAL L CA  1 
ATOM 337  C C   . VAL A 1 44  ? 394.777 360.838 494.867 1.00 74.80  ? 44  VAL L C   1 
ATOM 338  O O   . VAL A 1 44  ? 394.578 361.783 494.099 1.00 74.80  ? 44  VAL L O   1 
ATOM 339  C CB  . VAL A 1 44  ? 393.557 361.188 497.045 1.00 74.80  ? 44  VAL L CB  1 
ATOM 340  C CG1 . VAL A 1 44  ? 392.867 359.844 497.103 1.00 74.80  ? 44  VAL L CG1 1 
ATOM 341  C CG2 . VAL A 1 44  ? 393.708 361.762 498.430 1.00 74.80  ? 44  VAL L CG2 1 
ATOM 342  N N   . LYS A 1 45  ? 394.877 359.577 494.452 1.00 74.07  ? 45  LYS L N   1 
ATOM 343  C CA  . LYS A 1 45  ? 394.642 359.243 493.058 1.00 74.07  ? 45  LYS L CA  1 
ATOM 344  C C   . LYS A 1 45  ? 394.107 357.825 492.938 1.00 74.07  ? 45  LYS L C   1 
ATOM 345  O O   . LYS A 1 45  ? 394.224 357.008 493.854 1.00 74.07  ? 45  LYS L O   1 
ATOM 346  C CB  . LYS A 1 45  ? 395.905 359.407 492.216 1.00 74.07  ? 45  LYS L CB  1 
ATOM 347  C CG  . LYS A 1 45  ? 397.064 358.552 492.645 1.00 74.07  ? 45  LYS L CG  1 
ATOM 348  C CD  . LYS A 1 45  ? 398.273 358.778 491.750 1.00 74.07  ? 45  LYS L CD  1 
ATOM 349  C CE  . LYS A 1 45  ? 398.561 360.261 491.530 1.00 74.07  ? 45  LYS L CE  1 
ATOM 350  N NZ  . LYS A 1 45  ? 399.463 360.496 490.368 1.00 74.07  ? 45  LYS L NZ  1 
ATOM 351  N N   . LEU A 1 46  ? 393.519 357.552 491.776 1.00 75.16  ? 46  LEU L N   1 
ATOM 352  C CA  . LEU A 1 46  ? 392.832 356.302 491.489 1.00 75.16  ? 46  LEU L CA  1 
ATOM 353  C C   . LEU A 1 46  ? 393.810 355.314 490.876 1.00 75.16  ? 46  LEU L C   1 
ATOM 354  O O   . LEU A 1 46  ? 394.564 355.667 489.966 1.00 75.16  ? 46  LEU L O   1 
ATOM 355  C CB  . LEU A 1 46  ? 391.666 356.563 490.534 1.00 75.16  ? 46  LEU L CB  1 
ATOM 356  C CG  . LEU A 1 46  ? 391.011 355.426 489.749 1.00 75.16  ? 46  LEU L CG  1 
ATOM 357  C CD1 . LEU A 1 46  ? 390.001 354.693 490.591 1.00 75.16  ? 46  LEU L CD1 1 
ATOM 358  C CD2 . LEU A 1 46  ? 390.359 355.949 488.486 1.00 75.16  ? 46  LEU L CD2 1 
ATOM 359  N N   . LEU A 1 47  ? 393.794 354.079 491.369 1.00 76.45  ? 47  LEU L N   1 
ATOM 360  C CA  . LEU A 1 47  ? 394.693 353.042 490.877 1.00 76.45  ? 47  LEU L CA  1 
ATOM 361  C C   . LEU A 1 47  ? 393.984 352.068 489.946 1.00 76.45  ? 47  LEU L C   1 
ATOM 362  O O   . LEU A 1 47  ? 394.420 351.848 488.815 1.00 76.45  ? 47  LEU L O   1 
ATOM 363  C CB  . LEU A 1 47  ? 395.311 352.274 492.051 1.00 76.45  ? 47  LEU L CB  1 
ATOM 364  C CG  . LEU A 1 47  ? 396.323 352.974 492.950 1.00 76.45  ? 47  LEU L CG  1 
ATOM 365  C CD1 . LEU A 1 47  ? 396.923 351.962 493.886 1.00 76.45  ? 47  LEU L CD1 1 
ATOM 366  C CD2 . LEU A 1 47  ? 397.399 353.644 492.133 1.00 76.45  ? 47  LEU L CD2 1 
ATOM 367  N N   . ILE A 1 48  ? 392.894 351.473 490.412 1.00 74.41  ? 48  ILE L N   1 
ATOM 368  C CA  . ILE A 1 48  ? 392.225 350.371 489.735 1.00 74.41  ? 48  ILE L CA  1 
ATOM 369  C C   . ILE A 1 48  ? 390.743 350.707 489.725 1.00 74.41  ? 48  ILE L C   1 
ATOM 370  O O   . ILE A 1 48  ? 390.162 350.957 490.785 1.00 74.41  ? 48  ILE L O   1 
ATOM 371  C CB  . ILE A 1 48  ? 392.491 349.036 490.444 1.00 74.41  ? 48  ILE L CB  1 
ATOM 372  C CG1 . ILE A 1 48  ? 393.931 348.583 490.200 1.00 74.41  ? 48  ILE L CG1 1 
ATOM 373  C CG2 . ILE A 1 48  ? 391.515 347.979 490.012 1.00 74.41  ? 48  ILE L CG2 1 
ATOM 374  C CD1 . ILE A 1 48  ? 394.289 347.298 490.883 1.00 74.41  ? 48  ILE L CD1 1 
ATOM 375  N N   . TYR A 1 49  ? 390.127 350.739 488.540 1.00 71.62  ? 49  TYR L N   1 
ATOM 376  C CA  . TYR A 1 49  ? 388.757 351.224 488.447 1.00 71.62  ? 49  TYR L CA  1 
ATOM 377  C C   . TYR A 1 49  ? 387.734 350.128 488.177 1.00 71.62  ? 49  TYR L C   1 
ATOM 378  O O   . TYR A 1 49  ? 386.625 350.425 487.727 1.00 71.62  ? 49  TYR L O   1 
ATOM 379  C CB  . TYR A 1 49  ? 388.641 352.337 487.401 1.00 71.62  ? 49  TYR L CB  1 
ATOM 380  C CG  . TYR A 1 49  ? 389.100 352.064 485.986 1.00 71.62  ? 49  TYR L CG  1 
ATOM 381  C CD1 . TYR A 1 49  ? 388.332 351.318 485.108 1.00 71.62  ? 49  TYR L CD1 1 
ATOM 382  C CD2 . TYR A 1 49  ? 390.262 352.632 485.505 1.00 71.62  ? 49  TYR L CD2 1 
ATOM 383  C CE1 . TYR A 1 49  ? 388.730 351.109 483.817 1.00 71.62  ? 49  TYR L CE1 1 
ATOM 384  C CE2 . TYR A 1 49  ? 390.672 352.424 484.210 1.00 71.62  ? 49  TYR L CE2 1 
ATOM 385  C CZ  . TYR A 1 49  ? 389.903 351.660 483.374 1.00 71.62  ? 49  TYR L CZ  1 
ATOM 386  O OH  . TYR A 1 49  ? 390.308 351.449 482.082 1.00 71.62  ? 49  TYR L OH  1 
ATOM 387  N N   . TYR A 1 50  ? 388.074 348.879 488.447 1.00 75.72  ? 50  TYR L N   1 
ATOM 388  C CA  . TYR A 1 50  ? 387.147 347.760 488.379 1.00 75.72  ? 50  TYR L CA  1 
ATOM 389  C C   . TYR A 1 50  ? 387.684 346.767 489.400 1.00 75.72  ? 50  TYR L C   1 
ATOM 390  O O   . TYR A 1 50  ? 388.371 347.163 490.345 1.00 75.72  ? 50  TYR L O   1 
ATOM 391  C CB  . TYR A 1 50  ? 387.046 347.253 486.935 1.00 75.72  ? 50  TYR L CB  1 
ATOM 392  C CG  . TYR A 1 50  ? 385.808 346.477 486.559 1.00 75.72  ? 50  TYR L CG  1 
ATOM 393  C CD1 . TYR A 1 50  ? 384.576 347.107 486.476 1.00 75.72  ? 50  TYR L CD1 1 
ATOM 394  C CD2 . TYR A 1 50  ? 385.886 345.148 486.181 1.00 75.72  ? 50  TYR L CD2 1 
ATOM 395  C CE1 . TYR A 1 50  ? 383.443 346.417 486.093 1.00 75.72  ? 50  TYR L CE1 1 
ATOM 396  C CE2 . TYR A 1 50  ? 384.754 344.450 485.792 1.00 75.72  ? 50  TYR L CE2 1 
ATOM 397  C CZ  . TYR A 1 50  ? 383.537 345.094 485.751 1.00 75.72  ? 50  TYR L CZ  1 
ATOM 398  O OH  . TYR A 1 50  ? 382.411 344.407 485.371 1.00 75.72  ? 50  TYR L OH  1 
ATOM 399  N N   . THR A 1 51  ? 387.358 345.490 489.266 1.00 78.99  ? 51  THR L N   1 
ATOM 400  C CA  . THR A 1 51  ? 388.097 344.536 490.082 1.00 78.99  ? 51  THR L CA  1 
ATOM 401  C C   . THR A 1 51  ? 389.551 344.430 489.641 1.00 78.99  ? 51  THR L C   1 
ATOM 402  O O   . THR A 1 51  ? 390.449 344.340 490.482 1.00 78.99  ? 51  THR L O   1 
ATOM 403  C CB  . THR A 1 51  ? 387.442 343.164 490.050 1.00 78.99  ? 51  THR L CB  1 
ATOM 404  O OG1 . THR A 1 51  ? 387.485 342.636 488.720 1.00 78.99  ? 51  THR L OG1 1 
ATOM 405  C CG2 . THR A 1 51  ? 386.038 343.259 490.526 1.00 78.99  ? 51  THR L CG2 1 
ATOM 406  N N   . SER A 1 52  ? 389.814 344.461 488.337 1.00 77.36  ? 52  SER L N   1 
ATOM 407  C CA  . SER A 1 52  ? 391.113 343.982 487.889 1.00 77.36  ? 52  SER L CA  1 
ATOM 408  C C   . SER A 1 52  ? 391.790 344.798 486.797 1.00 77.36  ? 52  SER L C   1 
ATOM 409  O O   . SER A 1 52  ? 392.831 344.360 486.295 1.00 77.36  ? 52  SER L O   1 
ATOM 410  C CB  . SER A 1 52  ? 390.982 342.542 487.403 1.00 77.36  ? 52  SER L CB  1 
ATOM 411  O OG  . SER A 1 52  ? 390.643 342.510 486.029 1.00 77.36  ? 52  SER L OG  1 
ATOM 412  N N   . THR A 1 53  ? 391.266 345.949 486.390 1.00 74.44  ? 53  THR L N   1 
ATOM 413  C CA  . THR A 1 53  ? 391.919 346.721 485.340 1.00 74.44  ? 53  THR L CA  1 
ATOM 414  C C   . THR A 1 53  ? 392.527 347.994 485.913 1.00 74.44  ? 53  THR L C   1 
ATOM 415  O O   . THR A 1 53  ? 391.974 348.600 486.834 1.00 74.44  ? 53  THR L O   1 
ATOM 416  C CB  . THR A 1 53  ? 390.975 347.030 484.181 1.00 74.44  ? 53  THR L CB  1 
ATOM 417  O OG1 . THR A 1 53  ? 391.686 347.772 483.185 1.00 74.44  ? 53  THR L OG1 1 
ATOM 418  C CG2 . THR A 1 53  ? 389.787 347.804 484.622 1.00 74.44  ? 53  THR L CG2 1 
ATOM 419  N N   . LEU A 1 54  ? 393.689 348.362 485.389 1.00 75.26  ? 54  LEU L N   1 
ATOM 420  C CA  . LEU A 1 54  ? 394.481 349.445 485.945 1.00 75.26  ? 54  LEU L CA  1 
ATOM 421  C C   . LEU A 1 54  ? 394.107 350.774 485.313 1.00 75.26  ? 54  LEU L C   1 
ATOM 422  O O   . LEU A 1 54  ? 393.597 350.822 484.194 1.00 75.26  ? 54  LEU L O   1 
ATOM 423  C CB  . LEU A 1 54  ? 395.964 349.171 485.714 1.00 75.26  ? 54  LEU L CB  1 
ATOM 424  C CG  . LEU A 1 54  ? 396.545 347.995 486.488 1.00 75.26  ? 54  LEU L CG  1 
ATOM 425  C CD1 . LEU A 1 54  ? 397.711 347.390 485.739 1.00 75.26  ? 54  LEU L CD1 1 
ATOM 426  C CD2 . LEU A 1 54  ? 396.982 348.465 487.841 1.00 75.26  ? 54  LEU L CD2 1 
ATOM 427  N N   . HIS A 1 55  ? 394.366 351.854 486.036 1.00 76.93  ? 55  HIS L N   1 
ATOM 428  C CA  . HIS A 1 55  ? 394.287 353.173 485.433 1.00 76.93  ? 55  HIS L CA  1 
ATOM 429  C C   . HIS A 1 55  ? 395.487 353.392 484.521 1.00 76.93  ? 55  HIS L C   1 
ATOM 430  O O   . HIS A 1 55  ? 396.547 352.790 484.701 1.00 76.93  ? 55  HIS L O   1 
ATOM 431  C CB  . HIS A 1 55  ? 394.234 354.251 486.513 1.00 76.93  ? 55  HIS L CB  1 
ATOM 432  C CG  . HIS A 1 55  ? 393.897 355.611 485.993 1.00 76.93  ? 55  HIS L CG  1 
ATOM 433  N ND1 . HIS A 1 55  ? 392.898 355.827 485.070 1.00 76.93  ? 55  HIS L ND1 1 
ATOM 434  C CD2 . HIS A 1 55  ? 394.432 356.825 486.258 1.00 76.93  ? 55  HIS L CD2 1 
ATOM 435  C CE1 . HIS A 1 55  ? 392.831 357.115 484.791 1.00 76.93  ? 55  HIS L CE1 1 
ATOM 436  N NE2 . HIS A 1 55  ? 393.749 357.743 485.500 1.00 76.93  ? 55  HIS L NE2 1 
ATOM 437  N N   . SER A 1 56  ? 395.309 354.252 483.522 1.00 81.45  ? 56  SER L N   1 
ATOM 438  C CA  . SER A 1 56  ? 396.391 354.565 482.600 1.00 81.45  ? 56  SER L CA  1 
ATOM 439  C C   . SER A 1 56  ? 397.422 355.455 483.278 1.00 81.45  ? 56  SER L C   1 
ATOM 440  O O   . SER A 1 56  ? 397.079 356.473 483.883 1.00 81.45  ? 56  SER L O   1 
ATOM 441  C CB  . SER A 1 56  ? 395.844 355.259 481.358 1.00 81.45  ? 56  SER L CB  1 
ATOM 442  O OG  . SER A 1 56  ? 395.796 356.661 481.553 1.00 81.45  ? 56  SER L OG  1 
ATOM 443  N N   . GLY A 1 57  ? 398.687 355.077 483.162 1.00 81.98  ? 57  GLY L N   1 
ATOM 444  C CA  . GLY A 1 57  ? 399.761 355.788 483.816 1.00 81.98  ? 57  GLY L CA  1 
ATOM 445  C C   . GLY A 1 57  ? 400.215 355.190 485.123 1.00 81.98  ? 57  GLY L C   1 
ATOM 446  O O   . GLY A 1 57  ? 401.207 355.660 485.687 1.00 81.98  ? 57  GLY L O   1 
ATOM 447  N N   . VAL A 1 58  ? 399.524 354.178 485.619 1.00 82.62  ? 58  VAL L N   1 
ATOM 448  C CA  . VAL A 1 58  ? 399.904 353.475 486.839 1.00 82.62  ? 58  VAL L CA  1 
ATOM 449  C C   . VAL A 1 58  ? 400.703 352.246 486.426 1.00 82.62  ? 58  VAL L C   1 
ATOM 450  O O   . VAL A 1 58  ? 400.269 351.524 485.518 1.00 82.62  ? 58  VAL L O   1 
ATOM 451  C CB  . VAL A 1 58  ? 398.662 353.086 487.665 1.00 82.62  ? 58  VAL L CB  1 
ATOM 452  C CG1 . VAL A 1 58  ? 398.964 351.988 488.669 1.00 82.62  ? 58  VAL L CG1 1 
ATOM 453  C CG2 . VAL A 1 58  ? 398.125 354.306 488.377 1.00 82.62  ? 58  VAL L CG2 1 
ATOM 454  N N   . PRO A 1 59  ? 401.871 351.998 487.026 1.00 86.24  ? 59  PRO L N   1 
ATOM 455  C CA  . PRO A 1 59  ? 402.738 350.907 486.558 1.00 86.24  ? 59  PRO L CA  1 
ATOM 456  C C   . PRO A 1 59  ? 402.128 349.534 486.787 1.00 86.24  ? 59  PRO L C   1 
ATOM 457  O O   . PRO A 1 59  ? 401.163 349.372 487.533 1.00 86.24  ? 59  PRO L O   1 
ATOM 458  C CB  . PRO A 1 59  ? 404.011 351.090 487.391 1.00 86.24  ? 59  PRO L CB  1 
ATOM 459  C CG  . PRO A 1 59  ? 403.967 352.512 487.843 1.00 86.24  ? 59  PRO L CG  1 
ATOM 460  C CD  . PRO A 1 59  ? 402.527 352.817 488.055 1.00 86.24  ? 59  PRO L CD  1 
ATOM 461  N N   . SER A 1 60  ? 402.715 348.534 486.140 1.00 85.85  ? 60  SER L N   1 
ATOM 462  C CA  . SER A 1 60  ? 402.148 347.194 486.114 1.00 85.85  ? 60  SER L CA  1 
ATOM 463  C C   . SER A 1 60  ? 402.542 346.340 487.309 1.00 85.85  ? 60  SER L C   1 
ATOM 464  O O   . SER A 1 60  ? 402.489 345.114 487.204 1.00 85.85  ? 60  SER L O   1 
ATOM 465  C CB  . SER A 1 60  ? 402.553 346.479 484.826 1.00 85.85  ? 60  SER L CB  1 
ATOM 466  O OG  . SER A 1 60  ? 401.685 345.394 484.552 1.00 85.85  ? 60  SER L OG  1 
ATOM 467  N N   . ARG A 1 61  ? 402.942 346.936 488.430 1.00 91.24  ? 61  ARG L N   1 
ATOM 468  C CA  . ARG A 1 61  ? 403.178 346.141 489.627 1.00 91.24  ? 61  ARG L CA  1 
ATOM 469  C C   . ARG A 1 61  ? 401.913 345.948 490.446 1.00 91.24  ? 61  ARG L C   1 
ATOM 470  O O   . ARG A 1 61  ? 401.928 345.175 491.408 1.00 91.24  ? 61  ARG L O   1 
ATOM 471  C CB  . ARG A 1 61  ? 404.255 346.783 490.497 1.00 91.24  ? 61  ARG L CB  1 
ATOM 472  C CG  . ARG A 1 61  ? 405.543 347.087 489.766 1.00 91.24  ? 61  ARG L CG  1 
ATOM 473  C CD  . ARG A 1 61  ? 406.621 347.565 490.729 1.00 91.24  ? 61  ARG L CD  1 
ATOM 474  N NE  . ARG A 1 61  ? 406.153 348.583 491.670 1.00 91.24  ? 61  ARG L NE  1 
ATOM 475  C CZ  . ARG A 1 61  ? 406.037 349.876 491.384 1.00 91.24  ? 61  ARG L CZ  1 
ATOM 476  N NH1 . ARG A 1 61  ? 406.343 350.324 490.175 1.00 91.24  ? 61  ARG L NH1 1 
ATOM 477  N NH2 . ARG A 1 61  ? 405.614 350.724 492.311 1.00 91.24  ? 61  ARG L NH2 1 
ATOM 478  N N   . PHE A 1 62  ? 400.829 346.629 490.096 1.00 82.90  ? 62  PHE L N   1 
ATOM 479  C CA  . PHE A 1 62  ? 399.572 346.495 490.814 1.00 82.90  ? 62  PHE L CA  1 
ATOM 480  C C   . PHE A 1 62  ? 398.644 345.539 490.080 1.00 82.90  ? 62  PHE L C   1 
ATOM 481  O O   . PHE A 1 62  ? 398.678 345.447 488.851 1.00 82.90  ? 62  PHE L O   1 
ATOM 482  C CB  . PHE A 1 62  ? 398.886 347.850 490.970 1.00 82.90  ? 62  PHE L CB  1 
ATOM 483  C CG  . PHE A 1 62  ? 399.602 348.798 491.876 1.00 82.90  ? 62  PHE L CG  1 
ATOM 484  C CD1 . PHE A 1 62  ? 399.324 348.820 493.230 1.00 82.90  ? 62  PHE L CD1 1 
ATOM 485  C CD2 . PHE A 1 62  ? 400.538 349.683 491.372 1.00 82.90  ? 62  PHE L CD2 1 
ATOM 486  C CE1 . PHE A 1 62  ? 399.974 349.699 494.069 1.00 82.90  ? 62  PHE L CE1 1 
ATOM 487  C CE2 . PHE A 1 62  ? 401.191 350.567 492.207 1.00 82.90  ? 62  PHE L CE2 1 
ATOM 488  C CZ  . PHE A 1 62  ? 400.907 350.573 493.558 1.00 82.90  ? 62  PHE L CZ  1 
ATOM 489  N N   . SER A 1 63  ? 397.808 344.839 490.843 1.00 82.48  ? 63  SER L N   1 
ATOM 490  C CA  . SER A 1 63  ? 396.796 343.956 490.283 1.00 82.48  ? 63  SER L CA  1 
ATOM 491  C C   . SER A 1 63  ? 395.716 343.726 491.325 1.00 82.48  ? 63  SER L C   1 
ATOM 492  O O   . SER A 1 63  ? 395.987 343.737 492.527 1.00 82.48  ? 63  SER L O   1 
ATOM 493  C CB  . SER A 1 63  ? 397.391 342.616 489.848 1.00 82.48  ? 63  SER L CB  1 
ATOM 494  O OG  . SER A 1 63  ? 397.609 341.777 490.968 1.00 82.48  ? 63  SER L OG  1 
ATOM 495  N N   . GLY A 1 64  ? 394.493 343.500 490.851 1.00 79.09  ? 64  GLY L N   1 
ATOM 496  C CA  . GLY A 1 64  ? 393.378 343.246 491.731 1.00 79.09  ? 64  GLY L CA  1 
ATOM 497  C C   . GLY A 1 64  ? 392.647 341.979 491.332 1.00 79.09  ? 64  GLY L C   1 
ATOM 498  O O   . GLY A 1 64  ? 392.867 341.416 490.261 1.00 79.09  ? 64  GLY L O   1 
ATOM 499  N N   . SER A 1 65  ? 391.762 341.543 492.220 1.00 82.57  ? 65  SER L N   1 
ATOM 500  C CA  . SER A 1 65  ? 391.011 340.311 492.027 1.00 82.57  ? 65  SER L CA  1 
ATOM 501  C C   . SER A 1 65  ? 389.765 340.370 492.899 1.00 82.57  ? 65  SER L C   1 
ATOM 502  O O   . SER A 1 65  ? 389.539 341.345 493.622 1.00 82.57  ? 65  SER L O   1 
ATOM 503  C CB  . SER A 1 65  ? 391.868 339.089 492.365 1.00 82.57  ? 65  SER L CB  1 
ATOM 504  O OG  . SER A 1 65  ? 392.561 339.280 493.586 1.00 82.57  ? 65  SER L OG  1 
ATOM 505  N N   . GLY A 1 66  ? 388.960 339.314 492.842 1.00 84.24  ? 66  GLY L N   1 
ATOM 506  C CA  . GLY A 1 66  ? 387.808 339.208 493.712 1.00 84.24  ? 66  GLY L CA  1 
ATOM 507  C C   . GLY A 1 66  ? 386.525 338.825 493.008 1.00 84.24  ? 66  GLY L C   1 
ATOM 508  O O   . GLY A 1 66  ? 386.432 338.897 491.780 1.00 84.24  ? 66  GLY L O   1 
ATOM 509  N N   . SER A 1 67  ? 385.531 338.411 493.789 1.00 88.44  ? 67  SER L N   1 
ATOM 510  C CA  . SER A 1 67  ? 384.206 338.083 493.286 1.00 88.44  ? 67  SER L CA  1 
ATOM 511  C C   . SER A 1 67  ? 383.236 338.111 494.454 1.00 88.44  ? 67  SER L C   1 
ATOM 512  O O   . SER A 1 67  ? 383.574 337.668 495.554 1.00 88.44  ? 67  SER L O   1 
ATOM 513  C CB  . SER A 1 67  ? 384.169 336.705 492.617 1.00 88.44  ? 67  SER L CB  1 
ATOM 514  O OG  . SER A 1 67  ? 382.846 336.195 492.586 1.00 88.44  ? 67  SER L OG  1 
ATOM 515  N N   . GLY A 1 68  ? 382.038 338.626 494.208 1.00 88.61  ? 68  GLY L N   1 
ATOM 516  C CA  . GLY A 1 68  ? 381.020 338.646 495.236 1.00 88.61  ? 68  GLY L CA  1 
ATOM 517  C C   . GLY A 1 68  ? 381.279 339.667 496.321 1.00 88.61  ? 68  GLY L C   1 
ATOM 518  O O   . GLY A 1 68  ? 381.179 340.872 496.084 1.00 88.61  ? 68  GLY L O   1 
ATOM 519  N N   . THR A 1 69  ? 381.611 339.198 497.518 1.00 88.26  ? 69  THR L N   1 
ATOM 520  C CA  . THR A 1 69  ? 381.834 340.074 498.658 1.00 88.26  ? 69  THR L CA  1 
ATOM 521  C C   . THR A 1 69  ? 383.311 340.346 498.911 1.00 88.26  ? 69  THR L C   1 
ATOM 522  O O   . THR A 1 69  ? 383.687 341.481 499.216 1.00 88.26  ? 69  THR L O   1 
ATOM 523  C CB  . THR A 1 69  ? 381.192 339.460 499.909 1.00 88.26  ? 69  THR L CB  1 
ATOM 524  O OG1 . THR A 1 69  ? 379.798 339.246 499.667 1.00 88.26  ? 69  THR L OG1 1 
ATOM 525  C CG2 . THR A 1 69  ? 381.328 340.371 501.117 1.00 88.26  ? 69  THR L CG2 1 
ATOM 526  N N   . ASP A 1 70  ? 384.168 339.346 498.742 1.00 88.05  ? 70  ASP L N   1 
ATOM 527  C CA  . ASP A 1 70  ? 385.571 339.460 499.108 1.00 88.05  ? 70  ASP L CA  1 
ATOM 528  C C   . ASP A 1 70  ? 386.415 339.913 497.922 1.00 88.05  ? 70  ASP L C   1 
ATOM 529  O O   . ASP A 1 70  ? 386.275 339.396 496.811 1.00 88.05  ? 70  ASP L O   1 
ATOM 530  C CB  . ASP A 1 70  ? 386.078 338.122 499.637 1.00 88.05  ? 70  ASP L CB  1 
ATOM 531  C CG  . ASP A 1 70  ? 385.099 337.473 500.596 1.00 88.05  ? 70  ASP L CG  1 
ATOM 532  O OD1 . ASP A 1 70  ? 384.379 338.213 501.299 1.00 88.05  ? 70  ASP L OD1 1 
ATOM 533  O OD2 . ASP A 1 70  ? 385.046 336.227 500.645 1.00 88.05  ? 70  ASP L OD2 1 
ATOM 534  N N   . TYR A 1 71  ? 387.299 340.878 498.171 1.00 84.42  ? 71  TYR L N   1 
ATOM 535  C CA  . TYR A 1 71  ? 388.129 341.471 497.133 1.00 84.42  ? 71  TYR L CA  1 
ATOM 536  C C   . TYR A 1 71  ? 389.536 341.683 497.669 1.00 84.42  ? 71  TYR L C   1 
ATOM 537  O O   . TYR A 1 71  ? 389.765 341.697 498.880 1.00 84.42  ? 71  TYR L O   1 
ATOM 538  C CB  . TYR A 1 71  ? 387.547 342.795 496.646 1.00 84.42  ? 71  TYR L CB  1 
ATOM 539  C CG  . TYR A 1 71  ? 386.231 342.657 495.927 1.00 84.42  ? 71  TYR L CG  1 
ATOM 540  C CD1 . TYR A 1 71  ? 386.187 342.373 494.569 1.00 84.42  ? 71  TYR L CD1 1 
ATOM 541  C CD2 . TYR A 1 71  ? 385.035 342.819 496.601 1.00 84.42  ? 71  TYR L CD2 1 
ATOM 542  C CE1 . TYR A 1 71  ? 384.986 342.251 493.908 1.00 84.42  ? 71  TYR L CE1 1 
ATOM 543  C CE2 . TYR A 1 71  ? 383.835 342.698 495.949 1.00 84.42  ? 71  TYR L CE2 1 
ATOM 544  C CZ  . TYR A 1 71  ? 383.816 342.417 494.605 1.00 84.42  ? 71  TYR L CZ  1 
ATOM 545  O OH  . TYR A 1 71  ? 382.615 342.296 493.956 1.00 84.42  ? 71  TYR L OH  1 
ATOM 546  N N   . SER A 1 72  ? 390.484 341.877 496.754 1.00 83.70  ? 72  SER L N   1 
ATOM 547  C CA  . SER A 1 72  ? 391.887 341.910 497.134 1.00 83.70  ? 72  SER L CA  1 
ATOM 548  C C   . SER A 1 72  ? 392.689 342.764 496.165 1.00 83.70  ? 72  SER L C   1 
ATOM 549  O O   . SER A 1 72  ? 392.326 342.931 495.000 1.00 83.70  ? 72  SER L O   1 
ATOM 550  C CB  . SER A 1 72  ? 392.474 340.501 497.177 1.00 83.70  ? 72  SER L CB  1 
ATOM 551  O OG  . SER A 1 72  ? 392.863 340.091 495.879 1.00 83.70  ? 72  SER L OG  1 
ATOM 552  N N   . LEU A 1 73  ? 393.801 343.291 496.671 1.00 82.75  ? 73  LEU L N   1 
ATOM 553  C CA  . LEU A 1 73  ? 394.787 344.023 495.887 1.00 82.75  ? 73  LEU L CA  1 
ATOM 554  C C   . LEU A 1 73  ? 396.087 343.237 495.964 1.00 82.75  ? 73  LEU L C   1 
ATOM 555  O O   . LEU A 1 73  ? 396.243 342.397 496.852 1.00 82.75  ? 73  LEU L O   1 
ATOM 556  C CB  . LEU A 1 73  ? 394.968 345.445 496.434 1.00 82.75  ? 73  LEU L CB  1 
ATOM 557  C CG  . LEU A 1 73  ? 395.835 346.488 495.728 1.00 82.75  ? 73  LEU L CG  1 
ATOM 558  C CD1 . LEU A 1 73  ? 395.074 347.135 494.600 1.00 82.75  ? 73  LEU L CD1 1 
ATOM 559  C CD2 . LEU A 1 73  ? 396.319 347.529 496.708 1.00 82.75  ? 73  LEU L CD2 1 
ATOM 560  N N   . THR A 1 74  ? 397.004 343.473 495.027 1.00 88.24  ? 74  THR L N   1 
ATOM 561  C CA  . THR A 1 74  ? 398.304 342.813 495.037 1.00 88.24  ? 74  THR L CA  1 
ATOM 562  C C   . THR A 1 74  ? 399.355 343.748 494.459 1.00 88.24  ? 74  THR L C   1 
ATOM 563  O O   . THR A 1 74  ? 399.155 344.322 493.385 1.00 88.24  ? 74  THR L O   1 
ATOM 564  C CB  . THR A 1 74  ? 398.263 341.505 494.245 1.00 88.24  ? 74  THR L CB  1 
ATOM 565  O OG1 . THR A 1 74  ? 397.264 340.640 494.796 1.00 88.24  ? 74  THR L OG1 1 
ATOM 566  C CG2 . THR A 1 74  ? 399.607 340.799 494.295 1.00 88.24  ? 74  THR L CG2 1 
ATOM 567  N N   . ILE A 1 75  ? 400.462 343.910 495.181 1.00 92.45  ? 75  ILE L N   1 
ATOM 568  C CA  . ILE A 1 75  ? 401.656 344.597 494.694 1.00 92.45  ? 75  ILE L CA  1 
ATOM 569  C C   . ILE A 1 75  ? 402.777 343.569 494.754 1.00 92.45  ? 75  ILE L C   1 
ATOM 570  O O   . ILE A 1 75  ? 403.143 343.107 495.840 1.00 92.45  ? 75  ILE L O   1 
ATOM 571  C CB  . ILE A 1 75  ? 401.996 345.840 495.524 1.00 92.45  ? 75  ILE L CB  1 
ATOM 572  C CG1 . ILE A 1 75  ? 400.726 346.593 495.918 1.00 92.45  ? 75  ILE L CG1 1 
ATOM 573  C CG2 . ILE A 1 75  ? 402.931 346.755 494.757 1.00 92.45  ? 75  ILE L CG2 1 
ATOM 574  C CD1 . ILE A 1 75  ? 400.916 347.567 497.049 1.00 92.45  ? 75  ILE L CD1 1 
ATOM 575  N N   . ASN A 1 76  ? 403.327 343.195 493.599 1.00 97.29  ? 76  ASN L N   1 
ATOM 576  C CA  . ASN A 1 76  ? 404.267 342.081 493.568 1.00 97.29  ? 76  ASN L CA  1 
ATOM 577  C C   . ASN A 1 76  ? 405.693 342.467 493.937 1.00 97.29  ? 76  ASN L C   1 
ATOM 578  O O   . ASN A 1 76  ? 406.404 341.647 494.523 1.00 97.29  ? 76  ASN L O   1 
ATOM 579  C CB  . ASN A 1 76  ? 404.240 341.399 492.195 1.00 97.29  ? 76  ASN L CB  1 
ATOM 580  C CG  . ASN A 1 76  ? 404.399 342.370 491.037 1.00 97.29  ? 76  ASN L CG  1 
ATOM 581  O OD1 . ASN A 1 76  ? 404.946 343.462 491.176 1.00 97.29  ? 76  ASN L OD1 1 
ATOM 582  N ND2 . ASN A 1 76  ? 403.916 341.961 489.874 1.00 97.29  ? 76  ASN L ND2 1 
ATOM 583  N N   . SER A 1 77  ? 406.133 343.679 493.606 1.00 100.24 ? 77  SER L N   1 
ATOM 584  C CA  . SER A 1 77  ? 407.475 344.155 493.947 1.00 100.24 ? 77  SER L CA  1 
ATOM 585  C C   . SER A 1 77  ? 407.319 345.514 494.622 1.00 100.24 ? 77  SER L C   1 
ATOM 586  O O   . SER A 1 77  ? 407.147 346.535 493.953 1.00 100.24 ? 77  SER L O   1 
ATOM 587  C CB  . SER A 1 77  ? 408.362 344.224 492.715 1.00 100.24 ? 77  SER L CB  1 
ATOM 588  O OG  . SER A 1 77  ? 408.287 343.015 491.983 1.00 100.24 ? 77  SER L OG  1 
ATOM 589  N N   . LEU A 1 78  ? 407.370 345.511 495.949 1.00 103.61 ? 78  LEU L N   1 
ATOM 590  C CA  . LEU A 1 78  ? 407.155 346.720 496.727 1.00 103.61 ? 78  LEU L CA  1 
ATOM 591  C C   . LEU A 1 78  ? 408.349 347.656 496.572 1.00 103.61 ? 78  LEU L C   1 
ATOM 592  O O   . LEU A 1 78  ? 409.500 347.238 496.717 1.00 103.61 ? 78  LEU L O   1 
ATOM 593  C CB  . LEU A 1 78  ? 406.927 346.339 498.191 1.00 103.61 ? 78  LEU L CB  1 
ATOM 594  C CG  . LEU A 1 78  ? 406.114 347.174 499.188 1.00 103.61 ? 78  LEU L CG  1 
ATOM 595  C CD1 . LEU A 1 78  ? 405.801 346.324 500.396 1.00 103.61 ? 78  LEU L CD1 1 
ATOM 596  C CD2 . LEU A 1 78  ? 406.851 348.401 499.647 1.00 103.61 ? 78  LEU L CD2 1 
ATOM 597  N N   . GLU A 1 79  ? 408.074 348.917 496.262 1.00 105.74 ? 79  GLU L N   1 
ATOM 598  C CA  . GLU A 1 79  ? 409.095 349.933 496.037 1.00 105.74 ? 79  GLU L CA  1 
ATOM 599  C C   . GLU A 1 79  ? 409.008 350.987 497.132 1.00 105.74 ? 79  GLU L C   1 
ATOM 600  O O   . GLU A 1 79  ? 408.188 350.896 498.044 1.00 105.74 ? 79  GLU L O   1 
ATOM 601  C CB  . GLU A 1 79  ? 408.937 350.573 494.656 1.00 105.74 ? 79  GLU L CB  1 
ATOM 602  C CG  . GLU A 1 79  ? 409.174 349.625 493.496 1.00 105.74 ? 79  GLU L CG  1 
ATOM 603  C CD  . GLU A 1 79  ? 410.620 349.206 493.372 1.00 105.74 ? 79  GLU L CD  1 
ATOM 604  O OE1 . GLU A 1 79  ? 411.506 350.028 493.685 1.00 105.74 ? 79  GLU L OE1 1 
ATOM 605  O OE2 . GLU A 1 79  ? 410.871 348.054 492.963 1.00 105.74 ? 79  GLU L OE2 1 
ATOM 606  N N   . GLN A 1 80  ? 409.867 352.001 497.036 1.00 107.90 ? 80  GLN L N   1 
ATOM 607  C CA  . GLN A 1 80  ? 409.884 353.034 498.066 1.00 107.90 ? 80  GLN L CA  1 
ATOM 608  C C   . GLN A 1 80  ? 408.662 353.935 497.971 1.00 107.90 ? 80  GLN L C   1 
ATOM 609  O O   . GLN A 1 80  ? 408.060 354.284 498.992 1.00 107.90 ? 80  GLN L O   1 
ATOM 610  C CB  . GLN A 1 80  ? 411.166 353.860 497.964 1.00 107.90 ? 80  GLN L CB  1 
ATOM 611  C CG  . GLN A 1 80  ? 411.236 355.032 498.930 1.00 107.90 ? 80  GLN L CG  1 
ATOM 612  C CD  . GLN A 1 80  ? 411.245 354.596 500.383 1.00 107.90 ? 80  GLN L CD  1 
ATOM 613  O OE1 . GLN A 1 80  ? 411.770 353.538 500.727 1.00 107.90 ? 80  GLN L OE1 1 
ATOM 614  N NE2 . GLN A 1 80  ? 410.664 355.418 501.247 1.00 107.90 ? 80  GLN L NE2 1 
ATOM 615  N N   . GLU A 1 81  ? 408.254 354.285 496.754 1.00 105.12 ? 81  GLU L N   1 
ATOM 616  C CA  . GLU A 1 81  ? 407.168 355.231 496.533 1.00 105.12 ? 81  GLU L CA  1 
ATOM 617  C C   . GLU A 1 81  ? 405.790 354.666 496.848 1.00 105.12 ? 81  GLU L C   1 
ATOM 618  O O   . GLU A 1 81  ? 404.821 355.428 496.852 1.00 105.12 ? 81  GLU L O   1 
ATOM 619  C CB  . GLU A 1 81  ? 407.194 355.721 495.083 1.00 105.12 ? 81  GLU L CB  1 
ATOM 620  C CG  . GLU A 1 81  ? 407.487 354.632 494.061 1.00 105.12 ? 81  GLU L CG  1 
ATOM 621  C CD  . GLU A 1 81  ? 408.949 354.581 493.650 1.00 105.12 ? 81  GLU L CD  1 
ATOM 622  O OE1 . GLU A 1 81  ? 409.226 354.348 492.454 1.00 105.12 ? 81  GLU L OE1 1 
ATOM 623  O OE2 . GLU A 1 81  ? 409.820 354.774 494.523 1.00 105.12 ? 81  GLU L OE2 1 
ATOM 624  N N   . ASP A 1 82  ? 405.670 353.370 497.120 1.00 100.70 ? 82  ASP L N   1 
ATOM 625  C CA  . ASP A 1 82  ? 404.377 352.742 497.347 1.00 100.70 ? 82  ASP L CA  1 
ATOM 626  C C   . ASP A 1 82  ? 403.934 352.789 498.802 1.00 100.70 ? 82  ASP L C   1 
ATOM 627  O O   . ASP A 1 82  ? 402.899 352.208 499.137 1.00 100.70 ? 82  ASP L O   1 
ATOM 628  C CB  . ASP A 1 82  ? 404.411 351.292 496.873 1.00 100.70 ? 82  ASP L CB  1 
ATOM 629  C CG  . ASP A 1 82  ? 404.903 351.165 495.457 1.00 100.70 ? 82  ASP L CG  1 
ATOM 630  O OD1 . ASP A 1 82  ? 405.224 352.205 494.848 1.00 100.70 ? 82  ASP L OD1 1 
ATOM 631  O OD2 . ASP A 1 82  ? 404.965 350.029 494.948 1.00 100.70 ? 82  ASP L OD2 1 
ATOM 632  N N   . ILE A 1 83  ? 404.685 353.455 499.673 1.00 100.22 ? 83  ILE L N   1 
ATOM 633  C CA  . ILE A 1 83  ? 404.327 353.550 501.083 1.00 100.22 ? 83  ILE L CA  1 
ATOM 634  C C   . ILE A 1 83  ? 403.284 354.654 501.208 1.00 100.22 ? 83  ILE L C   1 
ATOM 635  O O   . ILE A 1 83  ? 403.618 355.837 501.276 1.00 100.22 ? 83  ILE L O   1 
ATOM 636  C CB  . ILE A 1 83  ? 405.544 353.820 501.967 1.00 100.22 ? 83  ILE L CB  1 
ATOM 637  C CG1 . ILE A 1 83  ? 406.682 352.863 501.622 1.00 100.22 ? 83  ILE L CG1 1 
ATOM 638  C CG2 . ILE A 1 83  ? 405.166 353.701 503.440 1.00 100.22 ? 83  ILE L CG2 1 
ATOM 639  C CD1 . ILE A 1 83  ? 406.324 351.412 501.809 1.00 100.22 ? 83  ILE L CD1 1 
ATOM 640  N N   . ALA A 1 84  ? 402.017 354.265 501.254 1.00 92.28  ? 84  ALA L N   1 
ATOM 641  C CA  . ALA A 1 84  ? 400.924 355.219 501.322 1.00 92.28  ? 84  ALA L CA  1 
ATOM 642  C C   . ALA A 1 84  ? 399.748 354.544 502.019 1.00 92.28  ? 84  ALA L C   1 
ATOM 643  O O   . ALA A 1 84  ? 399.891 353.466 502.604 1.00 92.28  ? 84  ALA L O   1 
ATOM 644  C CB  . ALA A 1 84  ? 400.570 355.721 499.921 1.00 92.28  ? 84  ALA L CB  1 
ATOM 645  N N   . THR A 1 85  ? 398.582 355.181 501.961 1.00 88.61  ? 85  THR L N   1 
ATOM 646  C CA  . THR A 1 85  ? 397.363 354.656 502.557 1.00 88.61  ? 85  THR L CA  1 
ATOM 647  C C   . THR A 1 85  ? 396.403 354.271 501.443 1.00 88.61  ? 85  THR L C   1 
ATOM 648  O O   . THR A 1 85  ? 396.373 354.922 500.397 1.00 88.61  ? 85  THR L O   1 
ATOM 649  C CB  . THR A 1 85  ? 396.720 355.685 503.479 1.00 88.61  ? 85  THR L CB  1 
ATOM 650  O OG1 . THR A 1 85  ? 397.747 356.404 504.167 1.00 88.61  ? 85  THR L OG1 1 
ATOM 651  C CG2 . THR A 1 85  ? 395.852 355.001 504.513 1.00 88.61  ? 85  THR L CG2 1 
ATOM 652  N N   . TYR A 1 86  ? 395.622 353.213 501.662 1.00 84.41  ? 86  TYR L N   1 
ATOM 653  C CA  . TYR A 1 86  ? 394.796 352.621 500.617 1.00 84.41  ? 86  TYR L CA  1 
ATOM 654  C C   . TYR A 1 86  ? 393.353 352.492 501.080 1.00 84.41  ? 86  TYR L C   1 
ATOM 655  O O   . TYR A 1 86  ? 393.098 352.181 502.247 1.00 84.41  ? 86  TYR L O   1 
ATOM 656  C CB  . TYR A 1 86  ? 395.346 351.256 500.214 1.00 84.41  ? 86  TYR L CB  1 
ATOM 657  C CG  . TYR A 1 86  ? 396.646 351.344 499.459 1.00 84.41  ? 86  TYR L CG  1 
ATOM 658  C CD1 . TYR A 1 86  ? 397.861 351.407 500.129 1.00 84.41  ? 86  TYR L CD1 1 
ATOM 659  C CD2 . TYR A 1 86  ? 396.659 351.374 498.076 1.00 84.41  ? 86  TYR L CD2 1 
ATOM 660  C CE1 . TYR A 1 86  ? 399.045 351.494 499.437 1.00 84.41  ? 86  TYR L CE1 1 
ATOM 661  C CE2 . TYR A 1 86  ? 397.839 351.460 497.379 1.00 84.41  ? 86  TYR L CE2 1 
ATOM 662  C CZ  . TYR A 1 86  ? 399.024 351.521 498.063 1.00 84.41  ? 86  TYR L CZ  1 
ATOM 663  O OH  . TYR A 1 86  ? 400.195 351.608 497.361 1.00 84.41  ? 86  TYR L OH  1 
ATOM 664  N N   . PHE A 1 87  ? 392.416 352.720 500.159 1.00 81.96  ? 87  PHE L N   1 
ATOM 665  C CA  . PHE A 1 87  ? 390.986 352.641 500.419 1.00 81.96  ? 87  PHE L CA  1 
ATOM 666  C C   . PHE A 1 87  ? 390.290 351.863 499.310 1.00 81.96  ? 87  PHE L C   1 
ATOM 667  O O   . PHE A 1 87  ? 390.768 351.800 498.177 1.00 81.96  ? 87  PHE L O   1 
ATOM 668  C CB  . PHE A 1 87  ? 390.346 354.029 500.504 1.00 81.96  ? 87  PHE L CB  1 
ATOM 669  C CG  . PHE A 1 87  ? 391.098 355.003 501.353 1.00 81.96  ? 87  PHE L CG  1 
ATOM 670  C CD1 . PHE A 1 87  ? 390.877 355.067 502.719 1.00 81.96  ? 87  PHE L CD1 1 
ATOM 671  C CD2 . PHE A 1 87  ? 392.001 355.879 500.785 1.00 81.96  ? 87  PHE L CD2 1 
ATOM 672  C CE1 . PHE A 1 87  ? 391.559 355.974 503.505 1.00 81.96  ? 87  PHE L CE1 1 
ATOM 673  C CE2 . PHE A 1 87  ? 392.688 356.781 501.568 1.00 81.96  ? 87  PHE L CE2 1 
ATOM 674  C CZ  . PHE A 1 87  ? 392.466 356.827 502.929 1.00 81.96  ? 87  PHE L CZ  1 
ATOM 675  N N   . CYS A 1 88  ? 389.139 351.288 499.637 1.00 84.39  ? 88  CYS L N   1 
ATOM 676  C CA  . CYS A 1 88  ? 388.270 350.659 498.653 1.00 84.39  ? 88  CYS L CA  1 
ATOM 677  C C   . CYS A 1 88  ? 386.908 351.333 498.691 1.00 84.39  ? 88  CYS L C   1 
ATOM 678  O O   . CYS A 1 88  ? 386.444 351.750 499.755 1.00 84.39  ? 88  CYS L O   1 
ATOM 679  C CB  . CYS A 1 88  ? 388.119 349.148 498.898 1.00 84.39  ? 88  CYS L CB  1 
ATOM 680  S SG  . CYS A 1 88  ? 387.454 348.672 500.517 1.00 84.39  ? 88  CYS L SG  1 
ATOM 681  N N   . GLN A 1 89  ? 386.267 351.438 497.530 1.00 76.04  ? 89  GLN L N   1 
ATOM 682  C CA  . GLN A 1 89  ? 384.982 352.113 497.401 1.00 76.04  ? 89  GLN L CA  1 
ATOM 683  C C   . GLN A 1 89  ? 384.124 351.373 496.388 1.00 76.04  ? 89  GLN L C   1 
ATOM 684  O O   . GLN A 1 89  ? 384.570 351.117 495.267 1.00 76.04  ? 89  GLN L O   1 
ATOM 685  C CB  . GLN A 1 89  ? 385.173 353.565 496.973 1.00 76.04  ? 89  GLN L CB  1 
ATOM 686  C CG  . GLN A 1 89  ? 383.907 354.243 496.512 1.00 76.04  ? 89  GLN L CG  1 
ATOM 687  C CD  . GLN A 1 89  ? 383.895 354.501 495.028 1.00 76.04  ? 89  GLN L CD  1 
ATOM 688  O OE1 . GLN A 1 89  ? 384.932 354.758 494.423 1.00 76.04  ? 89  GLN L OE1 1 
ATOM 689  N NE2 . GLN A 1 89  ? 382.719 354.436 494.430 1.00 76.04  ? 89  GLN L NE2 1 
ATOM 690  N N   . GLN A 1 90  ? 382.902 351.034 496.780 1.00 77.03  ? 90  GLN L N   1 
ATOM 691  C CA  . GLN A 1 90  ? 381.960 350.383 495.884 1.00 77.03  ? 90  GLN L CA  1 
ATOM 692  C C   . GLN A 1 90  ? 381.171 351.421 495.103 1.00 77.03  ? 90  GLN L C   1 
ATOM 693  O O   . GLN A 1 90  ? 380.996 352.557 495.545 1.00 77.03  ? 90  GLN L O   1 
ATOM 694  C CB  . GLN A 1 90  ? 380.999 349.492 496.664 1.00 77.03  ? 90  GLN L CB  1 
ATOM 695  C CG  . GLN A 1 90  ? 380.355 350.178 497.839 1.00 77.03  ? 90  GLN L CG  1 
ATOM 696  C CD  . GLN A 1 90  ? 379.003 350.744 497.501 1.00 77.03  ? 90  GLN L CD  1 
ATOM 697  O OE1 . GLN A 1 90  ? 378.462 350.474 496.433 1.00 77.03  ? 90  GLN L OE1 1 
ATOM 698  N NE2 . GLN A 1 90  ? 378.452 351.544 498.401 1.00 77.03  ? 90  GLN L NE2 1 
ATOM 699  N N   . GLY A 1 91  ? 380.681 351.018 493.939 1.00 75.42  ? 91  GLY L N   1 
ATOM 700  C CA  . GLY A 1 91  ? 379.903 351.919 493.117 1.00 75.42  ? 91  GLY L CA  1 
ATOM 701  C C   . GLY A 1 91  ? 378.580 351.320 492.698 1.00 75.42  ? 91  GLY L C   1 
ATOM 702  O O   . GLY A 1 91  ? 378.099 351.570 491.589 1.00 75.42  ? 91  GLY L O   1 
ATOM 703  N N   . ASN A 1 92  ? 377.979 350.523 493.581 1.00 75.08  ? 92  ASN L N   1 
ATOM 704  C CA  . ASN A 1 92  ? 376.755 349.811 493.240 1.00 75.08  ? 92  ASN L CA  1 
ATOM 705  C C   . ASN A 1 92  ? 375.510 350.566 493.693 1.00 75.08  ? 92  ASN L C   1 
ATOM 706  O O   . ASN A 1 92  ? 374.657 350.912 492.872 1.00 75.08  ? 92  ASN L O   1 
ATOM 707  C CB  . ASN A 1 92  ? 376.780 348.409 493.846 1.00 75.08  ? 92  ASN L CB  1 
ATOM 708  C CG  . ASN A 1 92  ? 376.233 347.371 492.903 1.00 75.08  ? 92  ASN L CG  1 
ATOM 709  O OD1 . ASN A 1 92  ? 376.080 347.626 491.711 1.00 75.08  ? 92  ASN L OD1 1 
ATOM 710  N ND2 . ASN A 1 92  ? 375.932 346.191 493.427 1.00 75.08  ? 92  ASN L ND2 1 
ATOM 711  N N   . THR A 1 93  ? 375.390 350.827 494.987 1.00 74.38  ? 93  THR L N   1 
ATOM 712  C CA  . THR A 1 93  ? 374.214 351.492 495.524 1.00 74.38  ? 93  THR L CA  1 
ATOM 713  C C   . THR A 1 93  ? 374.561 352.917 495.932 1.00 74.38  ? 93  THR L C   1 
ATOM 714  O O   . THR A 1 93  ? 375.677 353.396 495.727 1.00 74.38  ? 93  THR L O   1 
ATOM 715  C CB  . THR A 1 93  ? 373.637 350.729 496.719 1.00 74.38  ? 93  THR L CB  1 
ATOM 716  O OG1 . THR A 1 93  ? 374.432 350.989 497.880 1.00 74.38  ? 93  THR L OG1 1 
ATOM 717  C CG2 . THR A 1 93  ? 373.626 349.241 496.443 1.00 74.38  ? 93  THR L CG2 1 
ATOM 718  N N   . PHE A 1 94  ? 373.575 353.595 496.506 1.00 72.74  ? 94  PHE L N   1 
ATOM 719  C CA  . PHE A 1 94  ? 373.617 354.967 496.980 1.00 72.74  ? 94  PHE L CA  1 
ATOM 720  C C   . PHE A 1 94  ? 373.493 355.008 498.495 1.00 72.74  ? 94  PHE L C   1 
ATOM 721  O O   . PHE A 1 94  ? 372.628 354.335 499.062 1.00 72.74  ? 94  PHE L O   1 
ATOM 722  C CB  . PHE A 1 94  ? 372.482 355.780 496.358 1.00 72.74  ? 94  PHE L CB  1 
ATOM 723  C CG  . PHE A 1 94  ? 372.573 357.256 496.619 1.00 72.74  ? 94  PHE L CG  1 
ATOM 724  C CD1 . PHE A 1 94  ? 373.377 358.060 495.832 1.00 72.74  ? 94  PHE L CD1 1 
ATOM 725  C CD2 . PHE A 1 94  ? 371.843 357.842 497.642 1.00 72.74  ? 94  PHE L CD2 1 
ATOM 726  C CE1 . PHE A 1 94  ? 373.459 359.416 496.066 1.00 72.74  ? 94  PHE L CE1 1 
ATOM 727  C CE2 . PHE A 1 94  ? 371.923 359.194 497.879 1.00 72.74  ? 94  PHE L CE2 1 
ATOM 728  C CZ  . PHE A 1 94  ? 372.731 359.981 497.092 1.00 72.74  ? 94  PHE L CZ  1 
ATOM 729  N N   . PRO A 1 95  ? 374.323 355.792 499.199 1.00 74.09  ? 95  PRO L N   1 
ATOM 730  C CA  . PRO A 1 95  ? 375.399 356.640 498.689 1.00 74.09  ? 95  PRO L CA  1 
ATOM 731  C C   . PRO A 1 95  ? 376.706 355.890 498.575 1.00 74.09  ? 95  PRO L C   1 
ATOM 732  O O   . PRO A 1 95  ? 376.771 354.738 498.987 1.00 74.09  ? 95  PRO L O   1 
ATOM 733  C CB  . PRO A 1 95  ? 375.500 357.723 499.745 1.00 74.09  ? 95  PRO L CB  1 
ATOM 734  C CG  . PRO A 1 95  ? 375.190 357.005 500.990 1.00 74.09  ? 95  PRO L CG  1 
ATOM 735  C CD  . PRO A 1 95  ? 374.153 355.970 500.648 1.00 74.09  ? 95  PRO L CD  1 
ATOM 736  N N   . PHE A 1 96  ? 377.729 356.537 498.025 1.00 75.02  ? 96  PHE L N   1 
ATOM 737  C CA  . PHE A 1 96  ? 379.032 355.907 497.874 1.00 75.02  ? 96  PHE L CA  1 
ATOM 738  C C   . PHE A 1 96  ? 379.695 355.757 499.234 1.00 75.02  ? 96  PHE L C   1 
ATOM 739  O O   . PHE A 1 96  ? 379.750 356.710 500.016 1.00 75.02  ? 96  PHE L O   1 
ATOM 740  C CB  . PHE A 1 96  ? 379.923 356.729 496.948 1.00 75.02  ? 96  PHE L CB  1 
ATOM 741  C CG  . PHE A 1 96  ? 379.432 356.803 495.536 1.00 75.02  ? 96  PHE L CG  1 
ATOM 742  C CD1 . PHE A 1 96  ? 378.684 355.775 494.990 1.00 75.02  ? 96  PHE L CD1 1 
ATOM 743  C CD2 . PHE A 1 96  ? 379.730 357.899 494.749 1.00 75.02  ? 96  PHE L CD2 1 
ATOM 744  C CE1 . PHE A 1 96  ? 378.235 355.846 493.687 1.00 75.02  ? 96  PHE L CE1 1 
ATOM 745  C CE2 . PHE A 1 96  ? 379.285 357.976 493.448 1.00 75.02  ? 96  PHE L CE2 1 
ATOM 746  C CZ  . PHE A 1 96  ? 378.538 356.948 492.916 1.00 75.02  ? 96  PHE L CZ  1 
ATOM 747  N N   . THR A 1 97  ? 380.192 354.559 499.517 1.00 77.06  ? 97  THR L N   1 
ATOM 748  C CA  . THR A 1 97  ? 380.830 354.253 500.788 1.00 77.06  ? 97  THR L CA  1 
ATOM 749  C C   . THR A 1 97  ? 382.283 353.886 500.549 1.00 77.06  ? 97  THR L C   1 
ATOM 750  O O   . THR A 1 97  ? 382.592 353.126 499.628 1.00 77.06  ? 97  THR L O   1 
ATOM 751  C CB  . THR A 1 97  ? 380.119 353.111 501.498 1.00 77.06  ? 97  THR L CB  1 
ATOM 752  O OG1 . THR A 1 97  ? 379.740 352.127 500.533 1.00 77.06  ? 97  THR L OG1 1 
ATOM 753  C CG2 . THR A 1 97  ? 378.889 353.616 502.215 1.00 77.06  ? 97  THR L CG2 1 
ATOM 754  N N   . PHE A 1 98  ? 383.163 354.422 501.379 1.00 77.97  ? 98  PHE L N   1 
ATOM 755  C CA  . PHE A 1 98  ? 384.585 354.149 501.288 1.00 77.97  ? 98  PHE L CA  1 
ATOM 756  C C   . PHE A 1 98  ? 385.002 353.213 502.410 1.00 77.97  ? 98  PHE L C   1 
ATOM 757  O O   . PHE A 1 98  ? 384.390 353.185 503.479 1.00 77.97  ? 98  PHE L O   1 
ATOM 758  C CB  . PHE A 1 98  ? 385.393 355.444 501.360 1.00 77.97  ? 98  PHE L CB  1 
ATOM 759  C CG  . PHE A 1 98  ? 385.300 356.281 500.124 1.00 77.97  ? 98  PHE L CG  1 
ATOM 760  C CD1 . PHE A 1 98  ? 384.214 357.115 499.913 1.00 77.97  ? 98  PHE L CD1 1 
ATOM 761  C CD2 . PHE A 1 98  ? 386.298 356.237 499.171 1.00 77.97  ? 98  PHE L CD2 1 
ATOM 762  C CE1 . PHE A 1 98  ? 384.125 357.883 498.774 1.00 77.97  ? 98  PHE L CE1 1 
ATOM 763  C CE2 . PHE A 1 98  ? 386.214 357.004 498.032 1.00 77.97  ? 98  PHE L CE2 1 
ATOM 764  C CZ  . PHE A 1 98  ? 385.126 357.829 497.834 1.00 77.97  ? 98  PHE L CZ  1 
ATOM 765  N N   . GLY A 1 99  ? 386.041 352.438 502.155 1.00 83.79  ? 99  GLY L N   1 
ATOM 766  C CA  . GLY A 1 99  ? 386.585 351.573 503.177 1.00 83.79  ? 99  GLY L CA  1 
ATOM 767  C C   . GLY A 1 99  ? 387.521 352.318 504.101 1.00 83.79  ? 99  GLY L C   1 
ATOM 768  O O   . GLY A 1 99  ? 387.845 353.482 503.888 1.00 83.79  ? 99  GLY L O   1 
ATOM 769  N N   . GLY A 1 100 ? 387.948 351.630 505.152 1.00 86.64  ? 100 GLY L N   1 
ATOM 770  C CA  . GLY A 1 100 ? 388.948 352.186 506.034 1.00 86.64  ? 100 GLY L CA  1 
ATOM 771  C C   . GLY A 1 100 ? 390.313 352.200 505.382 1.00 86.64  ? 100 GLY L C   1 
ATOM 772  O O   . GLY A 1 100 ? 390.581 351.515 504.397 1.00 86.64  ? 100 GLY L O   1 
ATOM 773  N N   . GLY A 1 101 ? 391.198 353.006 505.943 1.00 91.19  ? 101 GLY L N   1 
ATOM 774  C CA  . GLY A 1 101 ? 392.537 353.104 505.412 1.00 91.19  ? 101 GLY L CA  1 
ATOM 775  C C   . GLY A 1 101 ? 393.383 351.895 505.751 1.00 91.19  ? 101 GLY L C   1 
ATOM 776  O O   . GLY A 1 101 ? 393.023 351.038 506.558 1.00 91.19  ? 101 GLY L O   1 
ATOM 777  N N   . THR A 1 102 ? 394.538 351.822 505.096 1.00 92.55  ? 102 THR L N   1 
ATOM 778  C CA  . THR A 1 102 ? 395.529 350.797 505.410 1.00 92.55  ? 102 THR L CA  1 
ATOM 779  C C   . THR A 1 102 ? 396.908 351.389 505.176 1.00 92.55  ? 102 THR L C   1 
ATOM 780  O O   . THR A 1 102 ? 397.289 351.644 504.033 1.00 92.55  ? 102 THR L O   1 
ATOM 781  C CB  . THR A 1 102 ? 395.322 349.546 504.573 1.00 92.55  ? 102 THR L CB  1 
ATOM 782  O OG1 . THR A 1 102 ? 394.063 348.957 504.911 1.00 92.55  ? 102 THR L OG1 1 
ATOM 783  C CG2 . THR A 1 102 ? 396.417 348.551 504.857 1.00 92.55  ? 102 THR L CG2 1 
ATOM 784  N N   . LYS A 1 103 ? 397.646 351.609 506.256 1.00 97.91  ? 103 LYS L N   1 
ATOM 785  C CA  . LYS A 1 103 ? 398.973 352.195 506.186 1.00 97.91  ? 103 LYS L CA  1 
ATOM 786  C C   . LYS A 1 103 ? 400.020 351.094 506.088 1.00 97.91  ? 103 LYS L C   1 
ATOM 787  O O   . LYS A 1 103 ? 399.948 350.088 506.795 1.00 97.91  ? 103 LYS L O   1 
ATOM 788  C CB  . LYS A 1 103 ? 399.224 353.065 507.421 1.00 97.91  ? 103 LYS L CB  1 
ATOM 789  C CG  . LYS A 1 103 ? 400.600 353.711 507.504 1.00 97.91  ? 103 LYS L CG  1 
ATOM 790  C CD  . LYS A 1 103 ? 400.795 354.761 506.433 1.00 97.91  ? 103 LYS L CD  1 
ATOM 791  C CE  . LYS A 1 103 ? 399.948 355.985 506.709 1.00 97.91  ? 103 LYS L CE  1 
ATOM 792  N NZ  . LYS A 1 103 ? 400.420 356.715 507.911 1.00 97.91  ? 103 LYS L NZ  1 
ATOM 793  N N   . LEU A 1 104 ? 400.988 351.284 505.202 1.00 102.19 ? 104 LEU L N   1 
ATOM 794  C CA  . LEU A 1 104 ? 402.111 350.370 505.076 1.00 102.19 ? 104 LEU L CA  1 
ATOM 795  C C   . LEU A 1 104 ? 403.305 350.908 505.853 1.00 102.19 ? 104 LEU L C   1 
ATOM 796  O O   . LEU A 1 104 ? 403.386 352.104 506.143 1.00 102.19 ? 104 LEU L O   1 
ATOM 797  C CB  . LEU A 1 104 ? 402.491 350.162 503.608 1.00 102.19 ? 104 LEU L CB  1 
ATOM 798  C CG  . LEU A 1 104 ? 401.991 348.869 502.968 1.00 102.19 ? 104 LEU L CG  1 
ATOM 799  C CD1 . LEU A 1 104 ? 400.486 348.857 502.867 1.00 102.19 ? 104 LEU L CD1 1 
ATOM 800  C CD2 . LEU A 1 104 ? 402.606 348.700 501.599 1.00 102.19 ? 104 LEU L CD2 1 
ATOM 801  N N   . GLU A 1 105 ? 404.229 350.014 506.199 1.00 110.62 ? 105 GLU L N   1 
ATOM 802  C CA  . GLU A 1 105 ? 405.468 350.418 506.846 1.00 110.62 ? 105 GLU L CA  1 
ATOM 803  C C   . GLU A 1 105 ? 406.538 349.383 506.517 1.00 110.62 ? 105 GLU L C   1 
ATOM 804  O O   . GLU A 1 105 ? 406.246 348.205 506.312 1.00 110.62 ? 105 GLU L O   1 
ATOM 805  C CB  . GLU A 1 105 ? 405.276 350.591 508.365 1.00 110.62 ? 105 GLU L CB  1 
ATOM 806  C CG  . GLU A 1 105 ? 406.435 351.305 509.077 1.00 110.62 ? 105 GLU L CG  1 
ATOM 807  C CD  . GLU A 1 105 ? 406.177 351.578 510.548 1.00 110.62 ? 105 GLU L CD  1 
ATOM 808  O OE1 . GLU A 1 105 ? 405.116 351.168 511.061 1.00 110.62 ? 105 GLU L OE1 1 
ATOM 809  O OE2 . GLU A 1 105 ? 407.035 352.222 511.189 1.00 110.62 ? 105 GLU L OE2 1 
ATOM 810  N N   . ILE A 1 106 ? 407.784 349.844 506.430 1.00 112.89 ? 106 ILE L N   1 
ATOM 811  C CA  . ILE A 1 106 ? 408.929 348.962 506.267 1.00 112.89 ? 106 ILE L CA  1 
ATOM 812  C C   . ILE A 1 106 ? 409.110 348.159 507.551 1.00 112.89 ? 106 ILE L C   1 
ATOM 813  O O   . ILE A 1 106 ? 408.975 348.685 508.659 1.00 112.89 ? 106 ILE L O   1 
ATOM 814  C CB  . ILE A 1 106 ? 410.188 349.780 505.910 1.00 112.89 ? 106 ILE L CB  1 
ATOM 815  C CG1 . ILE A 1 106 ? 409.957 350.552 504.610 1.00 112.89 ? 106 ILE L CG1 1 
ATOM 816  C CG2 . ILE A 1 106 ? 411.415 348.894 505.742 1.00 112.89 ? 106 ILE L CG2 1 
ATOM 817  C CD1 . ILE A 1 106 ? 409.591 349.675 503.429 1.00 112.89 ? 106 ILE L CD1 1 
ATOM 818  N N   . ARG A 1 107 ? 409.403 346.861 507.401 1.00 114.69 ? 107 ARG L N   1 
ATOM 819  C CA  . ARG A 1 107 ? 409.371 345.938 508.536 1.00 114.69 ? 107 ARG L CA  1 
ATOM 820  C C   . ARG A 1 107 ? 410.536 346.169 509.495 1.00 114.69 ? 107 ARG L C   1 
ATOM 821  O O   . ARG A 1 107 ? 410.334 346.512 510.666 1.00 114.69 ? 107 ARG L O   1 
ATOM 822  C CB  . ARG A 1 107 ? 409.375 344.495 508.032 1.00 114.69 ? 107 ARG L CB  1 
ATOM 823  C CG  . ARG A 1 107 ? 409.078 343.472 509.110 1.00 114.69 ? 107 ARG L CG  1 
ATOM 824  C CD  . ARG A 1 107 ? 407.601 343.161 509.173 1.00 114.69 ? 107 ARG L CD  1 
ATOM 825  N NE  . ARG A 1 107 ? 407.098 342.650 507.901 1.00 114.69 ? 107 ARG L NE  1 
ATOM 826  C CZ  . ARG A 1 107 ? 407.131 341.371 507.537 1.00 114.69 ? 107 ARG L CZ  1 
ATOM 827  N NH1 . ARG A 1 107 ? 407.644 340.456 508.348 1.00 114.69 ? 107 ARG L NH1 1 
ATOM 828  N NH2 . ARG A 1 107 ? 406.650 341.004 506.358 1.00 114.69 ? 107 ARG L NH2 1 
ATOM 829  N N   . ARG A 1 108 ? 411.762 345.972 509.024 1.00 115.82 ? 108 ARG L N   1 
ATOM 830  C CA  . ARG A 1 108 ? 412.930 346.170 509.874 1.00 115.82 ? 108 ARG L CA  1 
ATOM 831  C C   . ARG A 1 108 ? 413.878 347.178 509.239 1.00 115.82 ? 108 ARG L C   1 
ATOM 832  O O   . ARG A 1 108 ? 414.175 347.100 508.049 1.00 115.82 ? 108 ARG L O   1 
ATOM 833  C CB  . ARG A 1 108 ? 413.657 344.845 510.124 1.00 115.82 ? 108 ARG L CB  1 
ATOM 834  C CG  . ARG A 1 108 ? 414.577 344.846 511.341 1.00 115.82 ? 108 ARG L CG  1 
ATOM 835  C CD  . ARG A 1 108 ? 413.898 344.237 512.559 1.00 115.82 ? 108 ARG L CD  1 
ATOM 836  N NE  . ARG A 1 108 ? 414.557 344.619 513.806 1.00 115.82 ? 108 ARG L NE  1 
ATOM 837  C CZ  . ARG A 1 108 ? 414.273 344.094 514.994 1.00 115.82 ? 108 ARG L CZ  1 
ATOM 838  N NH1 . ARG A 1 108 ? 413.343 343.155 515.102 1.00 115.82 ? 108 ARG L NH1 1 
ATOM 839  N NH2 . ARG A 1 108 ? 414.919 344.505 516.076 1.00 115.82 ? 108 ARG L NH2 1 
ATOM 840  O OXT . ARG A 1 108 ? 414.371 348.092 509.897 1.00 115.82 ? 108 ARG L OXT 1 
ATOM 841  N N   . VAL B 2 2   ? 394.200 371.160 483.800 1.00 79.56  ? 2   VAL H N   1 
ATOM 842  C CA  . VAL B 2 2   ? 393.845 369.750 483.880 1.00 79.56  ? 2   VAL H CA  1 
ATOM 843  C C   . VAL B 2 2   ? 393.679 369.332 485.339 1.00 79.56  ? 2   VAL H C   1 
ATOM 844  O O   . VAL B 2 2   ? 393.335 368.190 485.629 1.00 79.56  ? 2   VAL H O   1 
ATOM 845  C CB  . VAL B 2 2   ? 394.895 368.880 483.170 1.00 79.56  ? 2   VAL H CB  1 
ATOM 846  C CG1 . VAL B 2 2   ? 395.171 369.422 481.783 1.00 79.56  ? 2   VAL H CG1 1 
ATOM 847  C CG2 . VAL B 2 2   ? 396.177 368.830 483.971 1.00 79.56  ? 2   VAL H CG2 1 
ATOM 848  N N   . GLN B 2 3   ? 393.902 370.278 486.246 1.00 80.49  ? 3   GLN H N   1 
ATOM 849  C CA  . GLN B 2 3   ? 393.931 370.036 487.680 1.00 80.49  ? 3   GLN H CA  1 
ATOM 850  C C   . GLN B 2 3   ? 392.952 370.948 488.410 1.00 80.49  ? 3   GLN H C   1 
ATOM 851  O O   . GLN B 2 3   ? 392.440 371.921 487.856 1.00 80.49  ? 3   GLN H O   1 
ATOM 852  C CB  . GLN B 2 3   ? 395.357 370.218 488.215 1.00 80.49  ? 3   GLN H CB  1 
ATOM 853  C CG  . GLN B 2 3   ? 396.086 371.472 487.718 1.00 80.49  ? 3   GLN H CG  1 
ATOM 854  C CD  . GLN B 2 3   ? 395.775 372.733 488.513 1.00 80.49  ? 3   GLN H CD  1 
ATOM 855  O OE1 . GLN B 2 3   ? 395.202 372.676 489.597 1.00 80.49  ? 3   GLN H OE1 1 
ATOM 856  N NE2 . GLN B 2 3   ? 396.161 373.882 487.970 1.00 80.49  ? 3   GLN H NE2 1 
ATOM 857  N N   . LEU B 2 4   ? 392.707 370.622 489.678 1.00 77.75  ? 4   LEU H N   1 
ATOM 858  C CA  . LEU B 2 4   ? 391.821 371.396 490.538 1.00 77.75  ? 4   LEU H CA  1 
ATOM 859  C C   . LEU B 2 4   ? 392.633 372.122 491.597 1.00 77.75  ? 4   LEU H C   1 
ATOM 860  O O   . LEU B 2 4   ? 393.743 371.704 491.937 1.00 77.75  ? 4   LEU H O   1 
ATOM 861  C CB  . LEU B 2 4   ? 390.791 370.516 491.244 1.00 77.75  ? 4   LEU H CB  1 
ATOM 862  C CG  . LEU B 2 4   ? 389.950 369.504 490.477 1.00 77.75  ? 4   LEU H CG  1 
ATOM 863  C CD1 . LEU B 2 4   ? 388.863 368.990 491.393 1.00 77.75  ? 4   LEU H CD1 1 
ATOM 864  C CD2 . LEU B 2 4   ? 389.373 370.077 489.212 1.00 77.75  ? 4   LEU H CD2 1 
ATOM 865  N N   . GLN B 2 5   ? 392.061 373.190 492.141 1.00 83.07  ? 5   GLN H N   1 
ATOM 866  C CA  . GLN B 2 5   ? 392.700 373.978 493.186 1.00 83.07  ? 5   GLN H CA  1 
ATOM 867  C C   . GLN B 2 5   ? 391.656 374.315 494.236 1.00 83.07  ? 5   GLN H C   1 
ATOM 868  O O   . GLN B 2 5   ? 390.540 374.713 493.893 1.00 83.07  ? 5   GLN H O   1 
ATOM 869  C CB  . GLN B 2 5   ? 393.315 375.254 492.609 1.00 83.07  ? 5   GLN H CB  1 
ATOM 870  C CG  . GLN B 2 5   ? 394.087 376.085 493.610 1.00 83.07  ? 5   GLN H CG  1 
ATOM 871  C CD  . GLN B 2 5   ? 395.552 375.720 493.656 1.00 83.07  ? 5   GLN H CD  1 
ATOM 872  O OE1 . GLN B 2 5   ? 396.088 375.143 492.712 1.00 83.07  ? 5   GLN H OE1 1 
ATOM 873  N NE2 . GLN B 2 5   ? 396.211 376.060 494.755 1.00 83.07  ? 5   GLN H NE2 1 
ATOM 874  N N   . GLN B 2 6   ? 392.014 374.152 495.504 1.00 85.31  ? 6   GLN H N   1 
ATOM 875  C CA  . GLN B 2 6   ? 391.134 374.487 496.608 1.00 85.31  ? 6   GLN H CA  1 
ATOM 876  C C   . GLN B 2 6   ? 391.614 375.757 497.299 1.00 85.31  ? 6   GLN H C   1 
ATOM 877  O O   . GLN B 2 6   ? 392.586 376.392 496.890 1.00 85.31  ? 6   GLN H O   1 
ATOM 878  C CB  . GLN B 2 6   ? 391.059 373.331 497.599 1.00 85.31  ? 6   GLN H CB  1 
ATOM 879  C CG  . GLN B 2 6   ? 390.532 372.050 497.014 1.00 85.31  ? 6   GLN H CG  1 
ATOM 880  C CD  . GLN B 2 6   ? 389.740 371.255 498.019 1.00 85.31  ? 6   GLN H CD  1 
ATOM 881  O OE1 . GLN B 2 6   ? 389.143 371.814 498.932 1.00 85.31  ? 6   GLN H OE1 1 
ATOM 882  N NE2 . GLN B 2 6   ? 389.733 369.942 497.859 1.00 85.31  ? 6   GLN H NE2 1 
ATOM 883  N N   . SER B 2 7   ? 390.921 376.127 498.369 1.00 92.81  ? 7   SER H N   1 
ATOM 884  C CA  . SER B 2 7   ? 391.296 377.288 499.160 1.00 92.81  ? 7   SER H CA  1 
ATOM 885  C C   . SER B 2 7   ? 392.323 376.878 500.211 1.00 92.81  ? 7   SER H C   1 
ATOM 886  O O   . SER B 2 7   ? 392.853 375.765 500.195 1.00 92.81  ? 7   SER H O   1 
ATOM 887  C CB  . SER B 2 7   ? 390.067 377.915 499.805 1.00 92.81  ? 7   SER H CB  1 
ATOM 888  O OG  . SER B 2 7   ? 389.831 377.337 501.075 1.00 92.81  ? 7   SER H OG  1 
ATOM 889  N N   . ALA B 2 8   ? 392.616 377.773 501.146 1.00 100.09 ? 8   ALA H N   1 
ATOM 890  C CA  . ALA B 2 8   ? 393.582 377.473 502.185 1.00 100.09 ? 8   ALA H CA  1 
ATOM 891  C C   . ALA B 2 8   ? 392.864 377.026 503.455 1.00 100.09 ? 8   ALA H C   1 
ATOM 892  O O   . ALA B 2 8   ? 391.644 377.142 503.587 1.00 100.09 ? 8   ALA H O   1 
ATOM 893  C CB  . ALA B 2 8   ? 394.477 378.681 502.449 1.00 100.09 ? 8   ALA H CB  1 
ATOM 894  N N   . ALA B 2 9   ? 393.639 376.501 504.400 1.00 104.81 ? 9   ALA H N   1 
ATOM 895  C CA  . ALA B 2 9   ? 393.096 376.025 505.662 1.00 104.81 ? 9   ALA H CA  1 
ATOM 896  C C   . ALA B 2 9   ? 392.671 377.198 506.533 1.00 104.81 ? 9   ALA H C   1 
ATOM 897  O O   . ALA B 2 9   ? 393.286 378.266 506.514 1.00 104.81 ? 9   ALA H O   1 
ATOM 898  C CB  . ALA B 2 9   ? 394.131 375.178 506.391 1.00 104.81 ? 9   ALA H CB  1 
ATOM 899  N N   . GLU B 2 10  ? 391.610 376.995 507.305 1.00 108.79 ? 10  GLU H N   1 
ATOM 900  C CA  . GLU B 2 10  ? 390.996 378.077 508.060 1.00 108.79 ? 10  GLU H CA  1 
ATOM 901  C C   . GLU B 2 10  ? 390.791 377.673 509.516 1.00 108.79 ? 10  GLU H C   1 
ATOM 902  O O   . GLU B 2 10  ? 391.197 376.597 509.956 1.00 108.79 ? 10  GLU H O   1 
ATOM 903  C CB  . GLU B 2 10  ? 389.668 378.494 507.422 1.00 108.79 ? 10  GLU H CB  1 
ATOM 904  C CG  . GLU B 2 10  ? 389.797 379.343 506.150 1.00 108.79 ? 10  GLU H CG  1 
ATOM 905  C CD  . GLU B 2 10  ? 390.208 380.801 506.375 1.00 108.79 ? 10  GLU H CD  1 
ATOM 906  O OE1 . GLU B 2 10  ? 390.514 381.212 507.514 1.00 108.79 ? 10  GLU H OE1 1 
ATOM 907  O OE2 . GLU B 2 10  ? 390.224 381.555 505.380 1.00 108.79 ? 10  GLU H OE2 1 
ATOM 908  N N   . LEU B 2 11  ? 390.137 378.565 510.257 1.00 112.17 ? 11  LEU H N   1 
ATOM 909  C CA  . LEU B 2 11  ? 389.913 378.405 511.688 1.00 112.17 ? 11  LEU H CA  1 
ATOM 910  C C   . LEU B 2 11  ? 388.632 379.133 512.057 1.00 112.17 ? 11  LEU H C   1 
ATOM 911  O O   . LEU B 2 11  ? 388.405 380.252 511.590 1.00 112.17 ? 11  LEU H O   1 
ATOM 912  C CB  . LEU B 2 11  ? 391.091 378.964 512.490 1.00 112.17 ? 11  LEU H CB  1 
ATOM 913  C CG  . LEU B 2 11  ? 391.234 378.542 513.951 1.00 112.17 ? 11  LEU H CG  1 
ATOM 914  C CD1 . LEU B 2 11  ? 390.975 377.064 514.124 1.00 112.17 ? 11  LEU H CD1 1 
ATOM 915  C CD2 . LEU B 2 11  ? 392.614 378.904 514.468 1.00 112.17 ? 11  LEU H CD2 1 
ATOM 916  N N   . ALA B 2 12  ? 387.800 378.507 512.886 1.00 112.63 ? 12  ALA H N   1 
ATOM 917  C CA  . ALA B 2 12  ? 386.543 379.129 513.272 1.00 112.63 ? 12  ALA H CA  1 
ATOM 918  C C   . ALA B 2 12  ? 386.101 378.637 514.642 1.00 112.63 ? 12  ALA H C   1 
ATOM 919  O O   . ALA B 2 12  ? 386.502 377.563 515.099 1.00 112.63 ? 12  ALA H O   1 
ATOM 920  C CB  . ALA B 2 12  ? 385.442 378.853 512.248 1.00 112.63 ? 12  ALA H CB  1 
ATOM 921  N N   . ARG B 2 13  ? 385.261 379.442 515.284 1.00 114.32 ? 13  ARG H N   1 
ATOM 922  C CA  . ARG B 2 13  ? 384.682 379.110 516.572 1.00 114.32 ? 13  ARG H CA  1 
ATOM 923  C C   . ARG B 2 13  ? 383.470 378.210 516.373 1.00 114.32 ? 13  ARG H C   1 
ATOM 924  O O   . ARG B 2 13  ? 382.796 378.290 515.345 1.00 114.32 ? 13  ARG H O   1 
ATOM 925  C CB  . ARG B 2 13  ? 384.273 380.381 517.310 1.00 114.32 ? 13  ARG H CB  1 
ATOM 926  C CG  . ARG B 2 13  ? 385.136 381.607 517.015 1.00 114.32 ? 13  ARG H CG  1 
ATOM 927  C CD  . ARG B 2 13  ? 386.543 381.475 517.586 1.00 114.32 ? 13  ARG H CD  1 
ATOM 928  N NE  . ARG B 2 13  ? 386.532 381.106 518.997 1.00 114.32 ? 13  ARG H NE  1 
ATOM 929  C CZ  . ARG B 2 13  ? 386.549 381.980 519.993 1.00 114.32 ? 13  ARG H CZ  1 
ATOM 930  N NH1 . ARG B 2 13  ? 386.581 383.277 519.734 1.00 114.32 ? 13  ARG H NH1 1 
ATOM 931  N NH2 . ARG B 2 13  ? 386.535 381.556 521.246 1.00 114.32 ? 13  ARG H NH2 1 
ATOM 932  N N   . PRO B 2 14  ? 383.187 377.324 517.330 1.00 111.64 ? 14  PRO H N   1 
ATOM 933  C CA  . PRO B 2 14  ? 382.002 376.464 517.208 1.00 111.64 ? 14  PRO H CA  1 
ATOM 934  C C   . PRO B 2 14  ? 380.719 377.273 517.321 1.00 111.64 ? 14  PRO H C   1 
ATOM 935  O O   . PRO B 2 14  ? 380.497 377.985 518.301 1.00 111.64 ? 14  PRO H O   1 
ATOM 936  C CB  . PRO B 2 14  ? 382.157 375.479 518.373 1.00 111.64 ? 14  PRO H CB  1 
ATOM 937  C CG  . PRO B 2 14  ? 383.613 375.460 518.654 1.00 111.64 ? 14  PRO H CG  1 
ATOM 938  C CD  . PRO B 2 14  ? 384.064 376.875 518.424 1.00 111.64 ? 14  PRO H CD  1 
ATOM 939  N N   . GLY B 2 15  ? 379.874 377.151 516.300 1.00 107.04 ? 15  GLY H N   1 
ATOM 940  C CA  . GLY B 2 15  ? 378.690 377.960 516.149 1.00 107.04 ? 15  GLY H CA  1 
ATOM 941  C C   . GLY B 2 15  ? 378.711 378.874 514.941 1.00 107.04 ? 15  GLY H C   1 
ATOM 942  O O   . GLY B 2 15  ? 377.647 379.328 514.507 1.00 107.04 ? 15  GLY H O   1 
ATOM 943  N N   . ALA B 2 16  ? 379.889 379.144 514.384 1.00 104.85 ? 16  ALA H N   1 
ATOM 944  C CA  . ALA B 2 16  ? 380.033 380.039 513.247 1.00 104.85 ? 16  ALA H CA  1 
ATOM 945  C C   . ALA B 2 16  ? 379.974 379.243 511.943 1.00 104.85 ? 16  ALA H C   1 
ATOM 946  O O   . ALA B 2 16  ? 379.607 378.066 511.923 1.00 104.85 ? 16  ALA H O   1 
ATOM 947  C CB  . ALA B 2 16  ? 381.325 380.843 513.372 1.00 104.85 ? 16  ALA H CB  1 
ATOM 948  N N   . SER B 2 17  ? 380.332 379.887 510.832 1.00 98.99  ? 17  SER H N   1 
ATOM 949  C CA  . SER B 2 17  ? 380.216 379.284 509.514 1.00 98.99  ? 17  SER H CA  1 
ATOM 950  C C   . SER B 2 17  ? 381.536 379.388 508.762 1.00 98.99  ? 17  SER H C   1 
ATOM 951  O O   . SER B 2 17  ? 382.229 380.406 508.822 1.00 98.99  ? 17  SER H O   1 
ATOM 952  C CB  . SER B 2 17  ? 379.105 379.947 508.696 1.00 98.99  ? 17  SER H CB  1 
ATOM 953  O OG  . SER B 2 17  ? 379.311 379.744 507.311 1.00 98.99  ? 17  SER H OG  1 
ATOM 954  N N   . VAL B 2 18  ? 381.873 378.313 508.051 1.00 95.62  ? 18  VAL H N   1 
ATOM 955  C CA  . VAL B 2 18  ? 383.052 378.250 507.200 1.00 95.62  ? 18  VAL H CA  1 
ATOM 956  C C   . VAL B 2 18  ? 382.567 378.013 505.771 1.00 95.62  ? 18  VAL H C   1 
ATOM 957  O O   . VAL B 2 18  ? 381.591 377.304 505.539 1.00 95.62  ? 18  VAL H O   1 
ATOM 958  C CB  . VAL B 2 18  ? 384.027 377.137 507.645 1.00 95.62  ? 18  VAL H CB  1 
ATOM 959  C CG1 . VAL B 2 18  ? 385.346 377.179 506.874 1.00 95.62  ? 18  VAL H CG1 1 
ATOM 960  C CG2 . VAL B 2 18  ? 384.277 377.206 509.126 1.00 95.62  ? 18  VAL H CG2 1 
ATOM 961  N N   . LYS B 2 19  ? 383.259 378.618 504.808 1.00 90.30  ? 19  LYS H N   1 
ATOM 962  C CA  . LYS B 2 19  ? 382.925 378.421 503.403 1.00 90.30  ? 19  LYS H CA  1 
ATOM 963  C C   . LYS B 2 19  ? 384.207 378.190 502.621 1.00 90.30  ? 19  LYS H C   1 
ATOM 964  O O   . LYS B 2 19  ? 385.097 379.045 502.624 1.00 90.30  ? 19  LYS H O   1 
ATOM 965  C CB  . LYS B 2 19  ? 382.159 379.621 502.853 1.00 90.30  ? 19  LYS H CB  1 
ATOM 966  C CG  . LYS B 2 19  ? 382.092 379.667 501.344 1.00 90.30  ? 19  LYS H CG  1 
ATOM 967  C CD  . LYS B 2 19  ? 381.127 380.733 500.879 1.00 90.30  ? 19  LYS H CD  1 
ATOM 968  C CE  . LYS B 2 19  ? 379.704 380.352 501.225 1.00 90.30  ? 19  LYS H CE  1 
ATOM 969  N NZ  . LYS B 2 19  ? 379.346 379.049 500.607 1.00 90.30  ? 19  LYS H NZ  1 
ATOM 970  N N   . MET B 2 20  ? 384.305 377.039 501.966 1.00 89.87  ? 20  MET H N   1 
ATOM 971  C CA  . MET B 2 20  ? 385.477 376.682 501.185 1.00 89.87  ? 20  MET H CA  1 
ATOM 972  C C   . MET B 2 20  ? 385.225 376.941 499.708 1.00 89.87  ? 20  MET H C   1 
ATOM 973  O O   . MET B 2 20  ? 384.161 377.407 499.301 1.00 89.87  ? 20  MET H O   1 
ATOM 974  C CB  . MET B 2 20  ? 385.854 375.219 501.401 1.00 89.87  ? 20  MET H CB  1 
ATOM 975  C CG  . MET B 2 20  ? 386.677 374.955 502.635 1.00 89.87  ? 20  MET H CG  1 
ATOM 976  S SD  . MET B 2 20  ? 386.309 373.317 503.262 1.00 89.87  ? 20  MET H SD  1 
ATOM 977  C CE  . MET B 2 20  ? 384.570 373.522 503.594 1.00 89.87  ? 20  MET H CE  1 
ATOM 978  N N   . SER B 2 21  ? 386.230 376.629 498.895 1.00 86.79  ? 21  SER H N   1 
ATOM 979  C CA  . SER B 2 21  ? 386.124 376.745 497.450 1.00 86.79  ? 21  SER H CA  1 
ATOM 980  C C   . SER B 2 21  ? 386.919 375.616 496.822 1.00 86.79  ? 21  SER H C   1 
ATOM 981  O O   . SER B 2 21  ? 387.761 374.995 497.471 1.00 86.79  ? 21  SER H O   1 
ATOM 982  C CB  . SER B 2 21  ? 386.636 378.096 496.945 1.00 86.79  ? 21  SER H CB  1 
ATOM 983  O OG  . SER B 2 21  ? 386.165 379.159 497.753 1.00 86.79  ? 21  SER H OG  1 
ATOM 984  N N   . CYS B 2 22  ? 386.637 375.349 495.548 1.00 84.96  ? 22  CYS H N   1 
ATOM 985  C CA  . CYS B 2 22  ? 387.373 374.333 494.795 1.00 84.96  ? 22  CYS H CA  1 
ATOM 986  C C   . CYS B 2 22  ? 387.364 374.767 493.333 1.00 84.96  ? 22  CYS H C   1 
ATOM 987  O O   . CYS B 2 22  ? 386.428 374.448 492.599 1.00 84.96  ? 22  CYS H O   1 
ATOM 988  C CB  . CYS B 2 22  ? 386.750 372.956 494.985 1.00 84.96  ? 22  CYS H CB  1 
ATOM 989  S SG  . CYS B 2 22  ? 387.405 371.632 493.932 1.00 84.96  ? 22  CYS H SG  1 
ATOM 990  N N   . LYS B 2 23  ? 388.400 375.488 492.915 1.00 82.16  ? 23  LYS H N   1 
ATOM 991  C CA  . LYS B 2 23  ? 388.406 376.071 491.579 1.00 82.16  ? 23  LYS H CA  1 
ATOM 992  C C   . LYS B 2 23  ? 388.954 375.072 490.572 1.00 82.16  ? 23  LYS H C   1 
ATOM 993  O O   . LYS B 2 23  ? 390.080 374.586 490.717 1.00 82.16  ? 23  LYS H O   1 
ATOM 994  C CB  . LYS B 2 23  ? 389.225 377.356 491.540 1.00 82.16  ? 23  LYS H CB  1 
ATOM 995  C CG  . LYS B 2 23  ? 389.453 377.834 490.124 1.00 82.16  ? 23  LYS H CG  1 
ATOM 996  C CD  . LYS B 2 23  ? 390.132 379.172 490.055 1.00 82.16  ? 23  LYS H CD  1 
ATOM 997  C CE  . LYS B 2 23  ? 390.716 379.370 488.670 1.00 82.16  ? 23  LYS H CE  1 
ATOM 998  N NZ  . LYS B 2 23  ? 389.685 379.195 487.610 1.00 82.16  ? 23  LYS H NZ  1 
ATOM 999  N N   . ALA B 2 24  ? 388.168 374.784 489.544 1.00 81.01  ? 24  ALA H N   1 
ATOM 1000 C CA  . ALA B 2 24  ? 388.545 373.844 488.504 1.00 81.01  ? 24  ALA H CA  1 
ATOM 1001 C C   . ALA B 2 24  ? 389.076 374.591 487.291 1.00 81.01  ? 24  ALA H C   1 
ATOM 1002 O O   . ALA B 2 24  ? 388.605 375.684 486.970 1.00 81.01  ? 24  ALA H O   1 
ATOM 1003 C CB  . ALA B 2 24  ? 387.351 372.986 488.098 1.00 81.01  ? 24  ALA H CB  1 
ATOM 1004 N N   . SER B 2 25  ? 390.056 373.996 486.618 1.00 80.02  ? 25  SER H N   1 
ATOM 1005 C CA  . SER B 2 25  ? 390.602 374.585 485.407 1.00 80.02  ? 25  SER H CA  1 
ATOM 1006 C C   . SER B 2 25  ? 391.125 373.478 484.510 1.00 80.02  ? 25  SER H C   1 
ATOM 1007 O O   . SER B 2 25  ? 391.659 372.475 484.985 1.00 80.02  ? 25  SER H O   1 
ATOM 1008 C CB  . SER B 2 25  ? 391.719 375.581 485.716 1.00 80.02  ? 25  SER H CB  1 
ATOM 1009 O OG  . SER B 2 25  ? 392.717 374.982 486.515 1.00 80.02  ? 25  SER H OG  1 
ATOM 1010 N N   . GLY B 2 26  ? 390.967 373.676 483.204 1.00 77.98  ? 26  GLY H N   1 
ATOM 1011 C CA  . GLY B 2 26  ? 391.458 372.739 482.220 1.00 77.98  ? 26  GLY H CA  1 
ATOM 1012 C C   . GLY B 2 26  ? 390.399 372.040 481.399 1.00 77.98  ? 26  GLY H C   1 
ATOM 1013 O O   . GLY B 2 26  ? 390.753 371.256 480.512 1.00 77.98  ? 26  GLY H O   1 
ATOM 1014 N N   . TYR B 2 27  ? 389.121 372.298 481.654 1.00 75.47  ? 27  TYR H N   1 
ATOM 1015 C CA  . TYR B 2 27  ? 388.060 371.612 480.931 1.00 75.47  ? 27  TYR H CA  1 
ATOM 1016 C C   . TYR B 2 27  ? 386.795 372.452 480.978 1.00 75.47  ? 27  TYR H C   1 
ATOM 1017 O O   . TYR B 2 27  ? 386.753 373.522 481.586 1.00 75.47  ? 27  TYR H O   1 
ATOM 1018 C CB  . TYR B 2 27  ? 387.806 370.210 481.498 1.00 75.47  ? 27  TYR H CB  1 
ATOM 1019 C CG  . TYR B 2 27  ? 387.455 370.165 482.967 1.00 75.47  ? 27  TYR H CG  1 
ATOM 1020 C CD1 . TYR B 2 27  ? 388.446 370.111 483.936 1.00 75.47  ? 27  TYR H CD1 1 
ATOM 1021 C CD2 . TYR B 2 27  ? 386.134 370.143 483.382 1.00 75.47  ? 27  TYR H CD2 1 
ATOM 1022 C CE1 . TYR B 2 27  ? 388.128 370.063 485.269 1.00 75.47  ? 27  TYR H CE1 1 
ATOM 1023 C CE2 . TYR B 2 27  ? 385.809 370.095 484.713 1.00 75.47  ? 27  TYR H CE2 1 
ATOM 1024 C CZ  . TYR B 2 27  ? 386.810 370.054 485.649 1.00 75.47  ? 27  TYR H CZ  1 
ATOM 1025 O OH  . TYR B 2 27  ? 386.491 370.000 486.978 1.00 75.47  ? 27  TYR H OH  1 
ATOM 1026 N N   . THR B 2 28  ? 385.762 371.950 480.308 1.00 74.17  ? 28  THR H N   1 
ATOM 1027 C CA  . THR B 2 28  ? 384.448 372.573 480.362 1.00 74.17  ? 28  THR H CA  1 
ATOM 1028 C C   . THR B 2 28  ? 383.823 372.294 481.718 1.00 74.17  ? 28  THR H C   1 
ATOM 1029 O O   . THR B 2 28  ? 383.443 371.156 482.006 1.00 74.17  ? 28  THR H O   1 
ATOM 1030 C CB  . THR B 2 28  ? 383.562 372.039 479.244 1.00 74.17  ? 28  THR H CB  1 
ATOM 1031 O OG1 . THR B 2 28  ? 383.220 370.677 479.522 1.00 74.17  ? 28  THR H OG1 1 
ATOM 1032 C CG2 . THR B 2 28  ? 384.290 372.101 477.922 1.00 74.17  ? 28  THR H CG2 1 
ATOM 1033 N N   . PHE B 2 29  ? 383.711 373.338 482.542 1.00 73.50  ? 29  PHE H N   1 
ATOM 1034 C CA  . PHE B 2 29  ? 383.356 373.166 483.945 1.00 73.50  ? 29  PHE H CA  1 
ATOM 1035 C C   . PHE B 2 29  ? 381.923 372.689 484.122 1.00 73.50  ? 29  PHE H C   1 
ATOM 1036 O O   . PHE B 2 29  ? 381.629 371.964 485.076 1.00 73.50  ? 29  PHE H O   1 
ATOM 1037 C CB  . PHE B 2 29  ? 383.578 374.480 484.688 1.00 73.50  ? 29  PHE H CB  1 
ATOM 1038 C CG  . PHE B 2 29  ? 383.048 374.486 486.085 1.00 73.50  ? 29  PHE H CG  1 
ATOM 1039 C CD1 . PHE B 2 29  ? 383.642 373.717 487.063 1.00 73.50  ? 29  PHE H CD1 1 
ATOM 1040 C CD2 . PHE B 2 29  ? 381.953 375.262 486.420 1.00 73.50  ? 29  PHE H CD2 1 
ATOM 1041 C CE1 . PHE B 2 29  ? 383.158 373.723 488.348 1.00 73.50  ? 29  PHE H CE1 1 
ATOM 1042 C CE2 . PHE B 2 29  ? 381.463 375.270 487.703 1.00 73.50  ? 29  PHE H CE2 1 
ATOM 1043 C CZ  . PHE B 2 29  ? 382.067 374.500 488.668 1.00 73.50  ? 29  PHE H CZ  1 
ATOM 1044 N N   . THR B 2 30  ? 381.033 373.037 483.197 1.00 70.04  ? 30  THR H N   1 
ATOM 1045 C CA  . THR B 2 30  ? 379.617 372.730 483.334 1.00 70.04  ? 30  THR H CA  1 
ATOM 1046 C C   . THR B 2 30  ? 379.229 371.430 482.657 1.00 70.04  ? 30  THR H C   1 
ATOM 1047 O O   . THR B 2 30  ? 378.105 371.308 482.159 1.00 70.04  ? 30  THR H O   1 
ATOM 1048 C CB  . THR B 2 30  ? 378.777 373.876 482.781 1.00 70.04  ? 30  THR H CB  1 
ATOM 1049 O OG1 . THR B 2 30  ? 379.351 374.336 481.552 1.00 70.04  ? 30  THR H OG1 1 
ATOM 1050 C CG2 . THR B 2 30  ? 378.734 375.014 483.771 1.00 70.04  ? 30  THR H CG2 1 
ATOM 1051 N N   . THR B 2 31  ? 380.132 370.459 482.609 1.00 65.66  ? 31  THR H N   1 
ATOM 1052 C CA  . THR B 2 31  ? 379.828 369.129 482.101 1.00 65.66  ? 31  THR H CA  1 
ATOM 1053 C C   . THR B 2 31  ? 379.799 368.072 483.188 1.00 65.66  ? 31  THR H C   1 
ATOM 1054 O O   . THR B 2 31  ? 378.818 367.342 483.310 1.00 65.66  ? 31  THR H O   1 
ATOM 1055 C CB  . THR B 2 31  ? 380.854 368.727 481.040 1.00 65.66  ? 31  THR H CB  1 
ATOM 1056 O OG1 . THR B 2 31  ? 380.821 369.670 479.966 1.00 65.66  ? 31  THR H OG1 1 
ATOM 1057 C CG2 . THR B 2 31  ? 380.544 367.360 480.495 1.00 65.66  ? 31  THR H CG2 1 
ATOM 1058 N N   . TYR B 2 32  ? 380.841 367.997 483.999 1.00 65.06  ? 32  TYR H N   1 
ATOM 1059 C CA  . TYR B 2 32  ? 381.010 366.951 484.989 1.00 65.06  ? 32  TYR H CA  1 
ATOM 1060 C C   . TYR B 2 32  ? 380.562 367.453 486.351 1.00 65.06  ? 32  TYR H C   1 
ATOM 1061 O O   . TYR B 2 32  ? 380.700 368.636 486.667 1.00 65.06  ? 32  TYR H O   1 
ATOM 1062 C CB  . TYR B 2 32  ? 382.471 366.500 485.055 1.00 65.06  ? 32  TYR H CB  1 
ATOM 1063 C CG  . TYR B 2 32  ? 383.019 365.952 483.753 1.00 65.06  ? 32  TYR H CG  1 
ATOM 1064 C CD1 . TYR B 2 32  ? 383.547 366.794 482.784 1.00 65.06  ? 32  TYR H CD1 1 
ATOM 1065 C CD2 . TYR B 2 32  ? 383.017 364.590 483.503 1.00 65.06  ? 32  TYR H CD2 1 
ATOM 1066 C CE1 . TYR B 2 32  ? 384.042 366.297 481.605 1.00 65.06  ? 32  TYR H CE1 1 
ATOM 1067 C CE2 . TYR B 2 32  ? 383.514 364.083 482.326 1.00 65.06  ? 32  TYR H CE2 1 
ATOM 1068 C CZ  . TYR B 2 32  ? 384.026 364.939 481.382 1.00 65.06  ? 32  TYR H CZ  1 
ATOM 1069 O OH  . TYR B 2 32  ? 384.523 364.431 480.206 1.00 65.06  ? 32  TYR H OH  1 
ATOM 1070 N N   . THR B 2 33  ? 380.020 366.547 487.155 1.00 66.50  ? 33  THR H N   1 
ATOM 1071 C CA  . THR B 2 33  ? 379.569 366.908 488.487 1.00 66.50  ? 33  THR H CA  1 
ATOM 1072 C C   . THR B 2 33  ? 380.735 366.892 489.465 1.00 66.50  ? 33  THR H C   1 
ATOM 1073 O O   . THR B 2 33  ? 381.644 366.066 489.373 1.00 66.50  ? 33  THR H O   1 
ATOM 1074 C CB  . THR B 2 33  ? 378.483 365.953 488.967 1.00 66.50  ? 33  THR H CB  1 
ATOM 1075 O OG1 . THR B 2 33  ? 379.042 364.648 489.133 1.00 66.50  ? 33  THR H OG1 1 
ATOM 1076 C CG2 . THR B 2 33  ? 377.376 365.880 487.953 1.00 66.50  ? 33  THR H CG2 1 
ATOM 1077 N N   . MET B 2 34  ? 380.699 367.819 490.416 1.00 70.99  ? 34  MET H N   1 
ATOM 1078 C CA  . MET B 2 34  ? 381.764 367.975 491.396 1.00 70.99  ? 34  MET H CA  1 
ATOM 1079 C C   . MET B 2 34  ? 381.253 367.500 492.744 1.00 70.99  ? 34  MET H C   1 
ATOM 1080 O O   . MET B 2 34  ? 380.136 367.843 493.138 1.00 70.99  ? 34  MET H O   1 
ATOM 1081 C CB  . MET B 2 34  ? 382.229 369.425 491.477 1.00 70.99  ? 34  MET H CB  1 
ATOM 1082 C CG  . MET B 2 34  ? 383.661 369.581 491.938 1.00 70.99  ? 34  MET H CG  1 
ATOM 1083 S SD  . MET B 2 34  ? 384.844 369.278 490.618 1.00 70.99  ? 34  MET H SD  1 
ATOM 1084 C CE  . MET B 2 34  ? 384.116 370.235 489.298 1.00 70.99  ? 34  MET H CE  1 
ATOM 1085 N N   . HIS B 2 35  ? 382.069 366.723 493.445 1.00 70.70  ? 35  HIS H N   1 
ATOM 1086 C CA  . HIS B 2 35  ? 381.681 366.068 494.683 1.00 70.70  ? 35  HIS H CA  1 
ATOM 1087 C C   . HIS B 2 35  ? 382.464 366.640 495.853 1.00 70.70  ? 35  HIS H C   1 
ATOM 1088 O O   . HIS B 2 35  ? 383.321 367.506 495.689 1.00 70.70  ? 35  HIS H O   1 
ATOM 1089 C CB  . HIS B 2 35  ? 381.906 364.561 494.581 1.00 70.70  ? 35  HIS H CB  1 
ATOM 1090 C CG  . HIS B 2 35  ? 380.903 363.865 493.724 1.00 70.70  ? 35  HIS H CG  1 
ATOM 1091 N ND1 . HIS B 2 35  ? 380.107 362.846 494.192 1.00 70.70  ? 35  HIS H ND1 1 
ATOM 1092 C CD2 . HIS B 2 35  ? 380.560 364.048 492.430 1.00 70.70  ? 35  HIS H CD2 1 
ATOM 1093 C CE1 . HIS B 2 35  ? 379.317 362.427 493.222 1.00 70.70  ? 35  HIS H CE1 1 
ATOM 1094 N NE2 . HIS B 2 35  ? 379.570 363.142 492.142 1.00 70.70  ? 35  HIS H NE2 1 
ATOM 1095 N N   . TRP B 2 36  ? 382.159 366.143 497.048 1.00 74.44  ? 36  TRP H N   1 
ATOM 1096 C CA  . TRP B 2 36  ? 382.815 366.586 498.269 1.00 74.44  ? 36  TRP H CA  1 
ATOM 1097 C C   . TRP B 2 36  ? 382.932 365.414 499.228 1.00 74.44  ? 36  TRP H C   1 
ATOM 1098 O O   . TRP B 2 36  ? 381.925 364.789 499.568 1.00 74.44  ? 36  TRP H O   1 
ATOM 1099 C CB  . TRP B 2 36  ? 382.043 367.730 498.923 1.00 74.44  ? 36  TRP H CB  1 
ATOM 1100 C CG  . TRP B 2 36  ? 382.254 369.037 498.255 1.00 74.44  ? 36  TRP H CG  1 
ATOM 1101 C CD1 . TRP B 2 36  ? 381.502 369.578 497.264 1.00 74.44  ? 36  TRP H CD1 1 
ATOM 1102 C CD2 . TRP B 2 36  ? 383.296 369.974 498.525 1.00 74.44  ? 36  TRP H CD2 1 
ATOM 1103 N NE1 . TRP B 2 36  ? 382.008 370.796 496.897 1.00 74.44  ? 36  TRP H NE1 1 
ATOM 1104 C CE2 . TRP B 2 36  ? 383.113 371.061 497.659 1.00 74.44  ? 36  TRP H CE2 1 
ATOM 1105 C CE3 . TRP B 2 36  ? 384.369 369.997 499.416 1.00 74.44  ? 36  TRP H CE3 1 
ATOM 1106 C CZ2 . TRP B 2 36  ? 383.956 372.156 497.658 1.00 74.44  ? 36  TRP H CZ2 1 
ATOM 1107 C CZ3 . TRP B 2 36  ? 385.202 371.083 499.415 1.00 74.44  ? 36  TRP H CZ3 1 
ATOM 1108 C CH2 . TRP B 2 36  ? 384.993 372.150 498.543 1.00 74.44  ? 36  TRP H CH2 1 
ATOM 1109 N N   . VAL B 2 37  ? 384.158 365.107 499.653 1.00 78.40  ? 37  VAL H N   1 
ATOM 1110 C CA  . VAL B 2 37  ? 384.440 363.971 500.526 1.00 78.40  ? 37  VAL H CA  1 
ATOM 1111 C C   . VAL B 2 37  ? 385.143 364.487 501.772 1.00 78.40  ? 37  VAL H C   1 
ATOM 1112 O O   . VAL B 2 37  ? 386.052 365.318 501.675 1.00 78.40  ? 37  VAL H O   1 
ATOM 1113 C CB  . VAL B 2 37  ? 385.308 362.906 499.830 1.00 78.40  ? 37  VAL H CB  1 
ATOM 1114 C CG1 . VAL B 2 37  ? 385.199 361.600 500.557 1.00 78.40  ? 37  VAL H CG1 1 
ATOM 1115 C CG2 . VAL B 2 37  ? 384.926 362.724 498.373 1.00 78.40  ? 37  VAL H CG2 1 
ATOM 1116 N N   . LYS B 2 38  ? 384.731 363.991 502.936 1.00 82.60  ? 38  LYS H N   1 
ATOM 1117 C CA  . LYS B 2 38  ? 385.261 364.420 504.225 1.00 82.60  ? 38  LYS H CA  1 
ATOM 1118 C C   . LYS B 2 38  ? 386.112 363.313 504.831 1.00 82.60  ? 38  LYS H C   1 
ATOM 1119 O O   . LYS B 2 38  ? 385.659 362.170 504.938 1.00 82.60  ? 38  LYS H O   1 
ATOM 1120 C CB  . LYS B 2 38  ? 384.121 364.784 505.178 1.00 82.60  ? 38  LYS H CB  1 
ATOM 1121 C CG  . LYS B 2 38  ? 384.467 364.723 506.655 1.00 82.60  ? 38  LYS H CG  1 
ATOM 1122 C CD  . LYS B 2 38  ? 383.277 365.122 507.506 1.00 82.60  ? 38  LYS H CD  1 
ATOM 1123 C CE  . LYS B 2 38  ? 383.631 365.150 508.976 1.00 82.60  ? 38  LYS H CE  1 
ATOM 1124 N NZ  . LYS B 2 38  ? 382.545 365.750 509.792 1.00 82.60  ? 38  LYS H NZ  1 
ATOM 1125 N N   . GLN B 2 39  ? 387.335 363.650 505.235 1.00 84.85  ? 39  GLN H N   1 
ATOM 1126 C CA  . GLN B 2 39  ? 388.231 362.691 505.876 1.00 84.85  ? 39  GLN H CA  1 
ATOM 1127 C C   . GLN B 2 39  ? 388.491 363.117 507.314 1.00 84.85  ? 39  GLN H C   1 
ATOM 1128 O O   . GLN B 2 39  ? 389.330 363.985 507.572 1.00 84.85  ? 39  GLN H O   1 
ATOM 1129 C CB  . GLN B 2 39  ? 389.545 362.552 505.123 1.00 84.85  ? 39  GLN H CB  1 
ATOM 1130 C CG  . GLN B 2 39  ? 390.460 361.516 505.757 1.00 84.85  ? 39  GLN H CG  1 
ATOM 1131 C CD  . GLN B 2 39  ? 391.686 361.225 504.935 1.00 84.85  ? 39  GLN H CD  1 
ATOM 1132 O OE1 . GLN B 2 39  ? 392.256 362.114 504.308 1.00 84.85  ? 39  GLN H OE1 1 
ATOM 1133 N NE2 . GLN B 2 39  ? 392.102 359.969 504.929 1.00 84.85  ? 39  GLN H NE2 1 
ATOM 1134 N N   . ARG B 2 40  ? 387.772 362.504 508.246 1.00 92.13  ? 40  ARG H N   1 
ATOM 1135 C CA  . ARG B 2 40  ? 388.130 362.614 509.645 1.00 92.13  ? 40  ARG H CA  1 
ATOM 1136 C C   . ARG B 2 40  ? 389.425 361.832 509.874 1.00 92.13  ? 40  ARG H C   1 
ATOM 1137 O O   . ARG B 2 40  ? 389.630 360.779 509.265 1.00 92.13  ? 40  ARG H O   1 
ATOM 1138 C CB  . ARG B 2 40  ? 386.996 362.070 510.514 1.00 92.13  ? 40  ARG H CB  1 
ATOM 1139 C CG  . ARG B 2 40  ? 386.977 362.545 511.953 1.00 92.13  ? 40  ARG H CG  1 
ATOM 1140 C CD  . ARG B 2 40  ? 385.722 362.102 512.685 1.00 92.13  ? 40  ARG H CD  1 
ATOM 1141 N NE  . ARG B 2 40  ? 384.514 362.738 512.166 1.00 92.13  ? 40  ARG H NE  1 
ATOM 1142 C CZ  . ARG B 2 40  ? 383.495 362.078 511.624 1.00 92.13  ? 40  ARG H CZ  1 
ATOM 1143 N NH1 . ARG B 2 40  ? 383.531 360.759 511.532 1.00 92.13  ? 40  ARG H NH1 1 
ATOM 1144 N NH2 . ARG B 2 40  ? 382.436 362.735 511.178 1.00 92.13  ? 40  ARG H NH2 1 
ATOM 1145 N N   . PRO B 2 41  ? 390.337 362.342 510.713 1.00 95.70  ? 41  PRO H N   1 
ATOM 1146 C CA  . PRO B 2 41  ? 391.645 361.679 510.869 1.00 95.70  ? 41  PRO H CA  1 
ATOM 1147 C C   . PRO B 2 41  ? 391.601 360.321 511.557 1.00 95.70  ? 41  PRO H C   1 
ATOM 1148 O O   . PRO B 2 41  ? 392.610 359.605 511.523 1.00 95.70  ? 41  PRO H O   1 
ATOM 1149 C CB  . PRO B 2 41  ? 392.449 362.687 511.704 1.00 95.70  ? 41  PRO H CB  1 
ATOM 1150 C CG  . PRO B 2 41  ? 391.420 363.542 512.364 1.00 95.70  ? 41  PRO H CG  1 
ATOM 1151 C CD  . PRO B 2 41  ? 390.342 363.672 511.345 1.00 95.70  ? 41  PRO H CD  1 
ATOM 1152 N N   . GLY B 2 42  ? 390.487 359.936 512.167 1.00 97.97  ? 42  GLY H N   1 
ATOM 1153 C CA  . GLY B 2 42  ? 390.433 358.661 512.849 1.00 97.97  ? 42  GLY H CA  1 
ATOM 1154 C C   . GLY B 2 42  ? 389.962 357.525 511.968 1.00 97.97  ? 42  GLY H C   1 
ATOM 1155 O O   . GLY B 2 42  ? 390.387 356.380 512.140 1.00 97.97  ? 42  GLY H O   1 
ATOM 1156 N N   . GLN B 2 43  ? 389.095 357.830 511.006 1.00 95.65  ? 43  GLN H N   1 
ATOM 1157 C CA  . GLN B 2 43  ? 388.483 356.801 510.176 1.00 95.65  ? 43  GLN H CA  1 
ATOM 1158 C C   . GLN B 2 43  ? 388.741 357.069 508.700 1.00 95.65  ? 43  GLN H C   1 
ATOM 1159 O O   . GLN B 2 43  ? 389.559 357.924 508.349 1.00 95.65  ? 43  GLN H O   1 
ATOM 1160 C CB  . GLN B 2 43  ? 386.975 356.721 510.427 1.00 95.65  ? 43  GLN H CB  1 
ATOM 1161 C CG  . GLN B 2 43  ? 386.571 356.693 511.885 1.00 95.65  ? 43  GLN H CG  1 
ATOM 1162 C CD  . GLN B 2 43  ? 386.230 358.070 512.414 1.00 95.65  ? 43  GLN H CD  1 
ATOM 1163 O OE1 . GLN B 2 43  ? 387.098 358.937 512.527 1.00 95.65  ? 43  GLN H OE1 1 
ATOM 1164 N NE2 . GLN B 2 43  ? 384.959 358.280 512.738 1.00 95.65  ? 43  GLN H NE2 1 
ATOM 1165 N N   . GLY B 2 44  ? 388.045 356.338 507.832 1.00 88.75  ? 44  GLY H N   1 
ATOM 1166 C CA  . GLY B 2 44  ? 388.163 356.515 506.402 1.00 88.75  ? 44  GLY H CA  1 
ATOM 1167 C C   . GLY B 2 44  ? 387.372 357.705 505.895 1.00 88.75  ? 44  GLY H C   1 
ATOM 1168 O O   . GLY B 2 44  ? 386.903 358.556 506.652 1.00 88.75  ? 44  GLY H O   1 
ATOM 1169 N N   . LEU B 2 45  ? 387.226 357.754 504.576 1.00 82.54  ? 45  LEU H N   1 
ATOM 1170 C CA  . LEU B 2 45  ? 386.549 358.866 503.933 1.00 82.54  ? 45  LEU H CA  1 
ATOM 1171 C C   . LEU B 2 45  ? 385.039 358.751 504.118 1.00 82.54  ? 45  LEU H C   1 
ATOM 1172 O O   . LEU B 2 45  ? 384.486 357.663 504.283 1.00 82.54  ? 45  LEU H O   1 
ATOM 1173 C CB  . LEU B 2 45  ? 386.880 358.907 502.443 1.00 82.54  ? 45  LEU H CB  1 
ATOM 1174 C CG  . LEU B 2 45  ? 388.324 358.881 501.932 1.00 82.54  ? 45  LEU H CG  1 
ATOM 1175 C CD1 . LEU B 2 45  ? 388.386 359.373 500.503 1.00 82.54  ? 45  LEU H CD1 1 
ATOM 1176 C CD2 . LEU B 2 45  ? 389.236 359.716 502.775 1.00 82.54  ? 45  LEU H CD2 1 
ATOM 1177 N N   . GLU B 2 46  ? 384.368 359.899 504.086 1.00 83.18  ? 46  GLU H N   1 
ATOM 1178 C CA  . GLU B 2 46  ? 382.916 359.939 504.196 1.00 83.18  ? 46  GLU H CA  1 
ATOM 1179 C C   . GLU B 2 46  ? 382.360 360.840 503.109 1.00 83.18  ? 46  GLU H C   1 
ATOM 1180 O O   . GLU B 2 46  ? 382.882 361.933 502.880 1.00 83.18  ? 46  GLU H O   1 
ATOM 1181 C CB  . GLU B 2 46  ? 382.467 360.441 505.570 1.00 83.18  ? 46  GLU H CB  1 
ATOM 1182 C CG  . GLU B 2 46  ? 382.738 359.475 506.704 1.00 83.18  ? 46  GLU H CG  1 
ATOM 1183 C CD  . GLU B 2 46  ? 382.243 359.988 508.034 1.00 83.18  ? 46  GLU H CD  1 
ATOM 1184 O OE1 . GLU B 2 46  ? 381.800 361.151 508.093 1.00 83.18  ? 46  GLU H OE1 1 
ATOM 1185 O OE2 . GLU B 2 46  ? 382.291 359.224 509.019 1.00 83.18  ? 46  GLU H OE2 1 
ATOM 1186 N N   . TRP B 2 47  ? 381.294 360.389 502.464 1.00 75.49  ? 47  TRP H N   1 
ATOM 1187 C CA  . TRP B 2 47  ? 380.682 361.117 501.365 1.00 75.49  ? 47  TRP H CA  1 
ATOM 1188 C C   . TRP B 2 47  ? 379.750 362.196 501.895 1.00 75.49  ? 47  TRP H C   1 
ATOM 1189 O O   . TRP B 2 47  ? 379.056 361.999 502.894 1.00 75.49  ? 47  TRP H O   1 
ATOM 1190 C CB  . TRP B 2 47  ? 379.915 360.150 500.472 1.00 75.49  ? 47  TRP H CB  1 
ATOM 1191 C CG  . TRP B 2 47  ? 379.656 360.651 499.115 1.00 75.49  ? 47  TRP H CG  1 
ATOM 1192 C CD1 . TRP B 2 47  ? 380.568 360.864 498.136 1.00 75.49  ? 47  TRP H CD1 1 
ATOM 1193 C CD2 . TRP B 2 47  ? 378.385 360.984 498.563 1.00 75.49  ? 47  TRP H CD2 1 
ATOM 1194 N NE1 . TRP B 2 47  ? 379.946 361.321 497.003 1.00 75.49  ? 47  TRP H NE1 1 
ATOM 1195 C CE2 . TRP B 2 47  ? 378.602 361.401 497.242 1.00 75.49  ? 47  TRP H CE2 1 
ATOM 1196 C CE3 . TRP B 2 47  ? 377.082 360.975 499.062 1.00 75.49  ? 47  TRP H CE3 1 
ATOM 1197 C CZ2 . TRP B 2 47  ? 377.569 361.808 496.415 1.00 75.49  ? 47  TRP H CZ2 1 
ATOM 1198 C CZ3 . TRP B 2 47  ? 376.060 361.377 498.240 1.00 75.49  ? 47  TRP H CZ3 1 
ATOM 1199 C CH2 . TRP B 2 47  ? 376.307 361.788 496.932 1.00 75.49  ? 47  TRP H CH2 1 
ATOM 1200 N N   . ILE B 2 48  ? 379.736 363.341 501.222 1.00 76.37  ? 48  ILE H N   1 
ATOM 1201 C CA  . ILE B 2 48  ? 378.891 364.468 501.602 1.00 76.37  ? 48  ILE H CA  1 
ATOM 1202 C C   . ILE B 2 48  ? 377.799 364.710 500.571 1.00 76.37  ? 48  ILE H C   1 
ATOM 1203 O O   . ILE B 2 48  ? 376.612 364.653 500.888 1.00 76.37  ? 48  ILE H O   1 
ATOM 1204 C CB  . ILE B 2 48  ? 379.730 365.741 501.834 1.00 76.37  ? 48  ILE H CB  1 
ATOM 1205 C CG1 . ILE B 2 48  ? 380.696 365.531 502.991 1.00 76.37  ? 48  ILE H CG1 1 
ATOM 1206 C CG2 . ILE B 2 48  ? 378.828 366.922 502.105 1.00 76.37  ? 48  ILE H CG2 1 
ATOM 1207 C CD1 . ILE B 2 48  ? 381.562 366.718 503.257 1.00 76.37  ? 48  ILE H CD1 1 
ATOM 1208 N N   . GLY B 2 49  ? 378.179 364.980 499.333 1.00 72.99  ? 49  GLY H N   1 
ATOM 1209 C CA  . GLY B 2 49  ? 377.201 365.231 498.299 1.00 72.99  ? 49  GLY H CA  1 
ATOM 1210 C C   . GLY B 2 49  ? 377.879 365.728 497.046 1.00 72.99  ? 49  GLY H C   1 
ATOM 1211 O O   . GLY B 2 49  ? 379.105 365.751 496.940 1.00 72.99  ? 49  GLY H O   1 
ATOM 1212 N N   . TYR B 2 50  ? 377.048 366.132 496.093 1.00 69.37  ? 50  TYR H N   1 
ATOM 1213 C CA  . TYR B 2 50  ? 377.533 366.598 494.809 1.00 69.37  ? 50  TYR H CA  1 
ATOM 1214 C C   . TYR B 2 50  ? 376.625 367.705 494.315 1.00 69.37  ? 50  TYR H C   1 
ATOM 1215 O O   . TYR B 2 50  ? 375.559 367.958 494.875 1.00 69.37  ? 50  TYR H O   1 
ATOM 1216 C CB  . TYR B 2 50  ? 377.602 365.456 493.794 1.00 69.37  ? 50  TYR H CB  1 
ATOM 1217 C CG  . TYR B 2 50  ? 376.278 365.059 493.189 1.00 69.37  ? 50  TYR H CG  1 
ATOM 1218 C CD1 . TYR B 2 50  ? 375.379 364.282 493.893 1.00 69.37  ? 50  TYR H CD1 1 
ATOM 1219 C CD2 . TYR B 2 50  ? 375.947 365.435 491.897 1.00 69.37  ? 50  TYR H CD2 1 
ATOM 1220 C CE1 . TYR B 2 50  ? 374.179 363.911 493.336 1.00 69.37  ? 50  TYR H CE1 1 
ATOM 1221 C CE2 . TYR B 2 50  ? 374.753 365.070 491.336 1.00 69.37  ? 50  TYR H CE2 1 
ATOM 1222 C CZ  . TYR B 2 50  ? 373.874 364.310 492.058 1.00 69.37  ? 50  TYR H CZ  1 
ATOM 1223 O OH  . TYR B 2 50  ? 372.681 363.951 491.493 1.00 69.37  ? 50  TYR H OH  1 
ATOM 1224 N N   . ILE B 2 51  ? 377.054 368.366 493.247 1.00 68.83  ? 51  ILE H N   1 
ATOM 1225 C CA  . ILE B 2 51  ? 376.268 369.424 492.627 1.00 68.83  ? 51  ILE H CA  1 
ATOM 1226 C C   . ILE B 2 51  ? 376.404 369.313 491.118 1.00 68.83  ? 51  ILE H C   1 
ATOM 1227 O O   . ILE B 2 51  ? 377.513 369.276 490.583 1.00 68.83  ? 51  ILE H O   1 
ATOM 1228 C CB  . ILE B 2 51  ? 376.681 370.821 493.136 1.00 68.83  ? 51  ILE H CB  1 
ATOM 1229 C CG1 . ILE B 2 51  ? 376.044 371.911 492.286 1.00 68.83  ? 51  ILE H CG1 1 
ATOM 1230 C CG2 . ILE B 2 51  ? 378.195 370.977 493.228 1.00 68.83  ? 51  ILE H CG2 1 
ATOM 1231 C CD1 . ILE B 2 51  ? 376.270 373.288 492.823 1.00 68.83  ? 51  ILE H CD1 1 
ATOM 1232 N N   . ASN B 2 52  ? 375.273 369.225 490.434 1.00 65.66  ? 52  ASN H N   1 
ATOM 1233 C CA  . ASN B 2 52  ? 375.264 369.245 488.983 1.00 65.66  ? 52  ASN H CA  1 
ATOM 1234 C C   . ASN B 2 52  ? 375.376 370.697 488.558 1.00 65.66  ? 52  ASN H C   1 
ATOM 1235 O O   . ASN B 2 52  ? 374.419 371.457 488.753 1.00 65.66  ? 52  ASN H O   1 
ATOM 1236 C CB  . ASN B 2 52  ? 373.985 368.626 488.450 1.00 65.66  ? 52  ASN H CB  1 
ATOM 1237 C CG  . ASN B 2 52  ? 373.978 368.500 486.952 1.00 65.66  ? 52  ASN H CG  1 
ATOM 1238 O OD1 . ASN B 2 52  ? 375.023 368.515 486.308 1.00 65.66  ? 52  ASN H OD1 1 
ATOM 1239 N ND2 . ASN B 2 52  ? 372.792 368.374 486.382 1.00 65.66  ? 52  ASN H ND2 1 
ATOM 1240 N N   . PRO B 2 53  ? 376.507 371.137 488.001 1.00 65.72  ? 53  PRO H N   1 
ATOM 1241 C CA  . PRO B 2 53  ? 376.709 372.574 487.783 1.00 65.72  ? 53  PRO H CA  1 
ATOM 1242 C C   . PRO B 2 53  ? 375.853 373.150 486.680 1.00 65.72  ? 53  PRO H C   1 
ATOM 1243 O O   . PRO B 2 53  ? 375.565 374.348 486.716 1.00 65.72  ? 53  PRO H O   1 
ATOM 1244 C CB  . PRO B 2 53  ? 378.198 372.675 487.427 1.00 65.72  ? 53  PRO H CB  1 
ATOM 1245 C CG  . PRO B 2 53  ? 378.760 371.295 487.582 1.00 65.72  ? 53  PRO H CG  1 
ATOM 1246 C CD  . PRO B 2 53  ? 377.623 370.350 487.465 1.00 65.72  ? 53  PRO H CD  1 
ATOM 1247 N N   . SER B 2 54  ? 375.404 372.340 485.728 1.00 68.46  ? 54  SER H N   1 
ATOM 1248 C CA  . SER B 2 54  ? 374.628 372.844 484.605 1.00 68.46  ? 54  SER H CA  1 
ATOM 1249 C C   . SER B 2 54  ? 373.186 373.148 484.978 1.00 68.46  ? 54  SER H C   1 
ATOM 1250 O O   . SER B 2 54  ? 372.461 373.753 484.186 1.00 68.46  ? 54  SER H O   1 
ATOM 1251 C CB  . SER B 2 54  ? 374.659 371.840 483.454 1.00 68.46  ? 54  SER H CB  1 
ATOM 1252 O OG  . SER B 2 54  ? 375.911 371.865 482.795 1.00 68.46  ? 54  SER H OG  1 
ATOM 1253 N N   . SER B 2 55  ? 372.747 372.726 486.158 1.00 66.68  ? 55  SER H N   1 
ATOM 1254 C CA  . SER B 2 55  ? 371.381 372.954 486.599 1.00 66.68  ? 55  SER H CA  1 
ATOM 1255 C C   . SER B 2 55  ? 371.284 373.367 488.055 1.00 66.68  ? 55  SER H C   1 
ATOM 1256 O O   . SER B 2 55  ? 370.173 373.630 488.524 1.00 66.68  ? 55  SER H O   1 
ATOM 1257 C CB  . SER B 2 55  ? 370.541 371.697 486.374 1.00 66.68  ? 55  SER H CB  1 
ATOM 1258 O OG  . SER B 2 55  ? 370.618 370.843 487.496 1.00 66.68  ? 55  SER H OG  1 
ATOM 1259 N N   . ARG B 2 56  ? 372.414 373.411 488.771 1.00 69.06  ? 56  ARG H N   1 
ATOM 1260 C CA  . ARG B 2 56  ? 372.495 373.754 490.197 1.00 69.06  ? 56  ARG H CA  1 
ATOM 1261 C C   . ARG B 2 56  ? 371.626 372.841 491.055 1.00 69.06  ? 56  ARG H C   1 
ATOM 1262 O O   . ARG B 2 56  ? 371.001 373.280 492.020 1.00 69.06  ? 56  ARG H O   1 
ATOM 1263 C CB  . ARG B 2 56  ? 372.151 375.224 490.445 1.00 69.06  ? 56  ARG H CB  1 
ATOM 1264 C CG  . ARG B 2 56  ? 373.018 376.185 489.666 1.00 69.06  ? 56  ARG H CG  1 
ATOM 1265 C CD  . ARG B 2 56  ? 372.806 377.614 490.108 1.00 69.06  ? 56  ARG H CD  1 
ATOM 1266 N NE  . ARG B 2 56  ? 371.571 378.168 489.567 1.00 69.06  ? 56  ARG H NE  1 
ATOM 1267 C CZ  . ARG B 2 56  ? 371.504 378.868 488.440 1.00 69.06  ? 56  ARG H CZ  1 
ATOM 1268 N NH1 . ARG B 2 56  ? 372.602 379.095 487.736 1.00 69.06  ? 56  ARG H NH1 1 
ATOM 1269 N NH2 . ARG B 2 56  ? 370.342 379.343 488.016 1.00 69.06  ? 56  ARG H NH2 1 
ATOM 1270 N N   . TYR B 2 57  ? 371.585 371.562 490.702 1.00 67.81  ? 57  TYR H N   1 
ATOM 1271 C CA  . TYR B 2 57  ? 370.830 370.568 491.449 1.00 67.81  ? 57  TYR H CA  1 
ATOM 1272 C C   . TYR B 2 57  ? 371.779 369.790 492.342 1.00 67.81  ? 57  TYR H C   1 
ATOM 1273 O O   . TYR B 2 57  ? 372.671 369.098 491.847 1.00 67.81  ? 57  TYR H O   1 
ATOM 1274 C CB  . TYR B 2 57  ? 370.096 369.610 490.520 1.00 67.81  ? 57  TYR H CB  1 
ATOM 1275 C CG  . TYR B 2 57  ? 369.348 368.555 491.277 1.00 67.81  ? 57  TYR H CG  1 
ATOM 1276 C CD1 . TYR B 2 57  ? 368.242 368.888 492.038 1.00 67.81  ? 57  TYR H CD1 1 
ATOM 1277 C CD2 . TYR B 2 57  ? 369.752 367.228 491.248 1.00 67.81  ? 57  TYR H CD2 1 
ATOM 1278 C CE1 . TYR B 2 57  ? 367.549 367.932 492.745 1.00 67.81  ? 57  TYR H CE1 1 
ATOM 1279 C CE2 . TYR B 2 57  ? 369.063 366.261 491.954 1.00 67.81  ? 57  TYR H CE2 1 
ATOM 1280 C CZ  . TYR B 2 57  ? 367.962 366.625 492.700 1.00 67.81  ? 57  TYR H CZ  1 
ATOM 1281 O OH  . TYR B 2 57  ? 367.263 365.688 493.410 1.00 67.81  ? 57  TYR H OH  1 
ATOM 1282 N N   . THR B 2 58  ? 371.580 369.892 493.648 1.00 71.58  ? 58  THR H N   1 
ATOM 1283 C CA  . THR B 2 58  ? 372.427 369.234 494.627 1.00 71.58  ? 58  THR H CA  1 
ATOM 1284 C C   . THR B 2 58  ? 371.652 368.139 495.341 1.00 71.58  ? 58  THR H C   1 
ATOM 1285 O O   . THR B 2 58  ? 370.431 368.213 495.484 1.00 71.58  ? 58  THR H O   1 
ATOM 1286 C CB  . THR B 2 58  ? 372.949 370.229 495.655 1.00 71.58  ? 58  THR H CB  1 
ATOM 1287 O OG1 . THR B 2 58  ? 371.900 370.543 496.578 1.00 71.58  ? 58  THR H OG1 1 
ATOM 1288 C CG2 . THR B 2 58  ? 373.414 371.502 494.972 1.00 71.58  ? 58  THR H CG2 1 
ATOM 1289 N N   . GLU B 2 59  ? 372.378 367.125 495.801 1.00 74.98  ? 59  GLU H N   1 
ATOM 1290 C CA  . GLU B 2 59  ? 371.780 365.982 496.478 1.00 74.98  ? 59  GLU H CA  1 
ATOM 1291 C C   . GLU B 2 59  ? 372.751 365.477 497.531 1.00 74.98  ? 59  GLU H C   1 
ATOM 1292 O O   . GLU B 2 59  ? 373.837 365.003 497.194 1.00 74.98  ? 59  GLU H O   1 
ATOM 1293 C CB  . GLU B 2 59  ? 371.442 364.879 495.482 1.00 74.98  ? 59  GLU H CB  1 
ATOM 1294 C CG  . GLU B 2 59  ? 370.796 363.673 496.102 1.00 74.98  ? 59  GLU H CG  1 
ATOM 1295 C CD  . GLU B 2 59  ? 370.424 362.644 495.066 1.00 74.98  ? 59  GLU H CD  1 
ATOM 1296 O OE1 . GLU B 2 59  ? 369.279 362.142 495.091 1.00 74.98  ? 59  GLU H OE1 1 
ATOM 1297 O OE2 . GLU B 2 59  ? 371.282 362.347 494.213 1.00 74.98  ? 59  GLU H OE2 1 
ATOM 1298 N N   . TYR B 2 60  ? 372.355 365.561 498.794 1.00 79.16  ? 60  TYR H N   1 
ATOM 1299 C CA  . TYR B 2 60  ? 373.243 365.304 499.913 1.00 79.16  ? 60  TYR H CA  1 
ATOM 1300 C C   . TYR B 2 60  ? 373.005 363.926 500.509 1.00 79.16  ? 60  TYR H C   1 
ATOM 1301 O O   . TYR B 2 60  ? 371.903 363.378 500.454 1.00 79.16  ? 60  TYR H O   1 
ATOM 1302 C CB  . TYR B 2 60  ? 373.058 366.356 501.005 1.00 79.16  ? 60  TYR H CB  1 
ATOM 1303 C CG  . TYR B 2 60  ? 373.016 367.763 500.487 1.00 79.16  ? 60  TYR H CG  1 
ATOM 1304 C CD1 . TYR B 2 60  ? 374.180 368.433 500.156 1.00 79.16  ? 60  TYR H CD1 1 
ATOM 1305 C CD2 . TYR B 2 60  ? 371.812 368.427 500.333 1.00 79.16  ? 60  TYR H CD2 1 
ATOM 1306 C CE1 . TYR B 2 60  ? 374.144 369.720 499.682 1.00 79.16  ? 60  TYR H CE1 1 
ATOM 1307 C CE2 . TYR B 2 60  ? 371.768 369.719 499.857 1.00 79.16  ? 60  TYR H CE2 1 
ATOM 1308 C CZ  . TYR B 2 60  ? 372.938 370.359 499.534 1.00 79.16  ? 60  TYR H CZ  1 
ATOM 1309 O OH  . TYR B 2 60  ? 372.898 371.647 499.059 1.00 79.16  ? 60  TYR H OH  1 
ATOM 1310 N N   . ASN B 2 61  ? 374.069 363.373 501.083 1.00 83.13  ? 61  ASN H N   1 
ATOM 1311 C CA  . ASN B 2 61  ? 373.952 362.215 501.949 1.00 83.13  ? 61  ASN H CA  1 
ATOM 1312 C C   . ASN B 2 61  ? 373.143 362.591 503.185 1.00 83.13  ? 61  ASN H C   1 
ATOM 1313 O O   . ASN B 2 61  ? 373.159 363.737 503.638 1.00 83.13  ? 61  ASN H O   1 
ATOM 1314 C CB  . ASN B 2 61  ? 375.341 361.709 502.344 1.00 83.13  ? 61  ASN H CB  1 
ATOM 1315 C CG  . ASN B 2 61  ? 375.298 360.414 503.129 1.00 83.13  ? 61  ASN H CG  1 
ATOM 1316 O OD1 . ASN B 2 61  ? 374.392 359.606 502.960 1.00 83.13  ? 61  ASN H OD1 1 
ATOM 1317 N ND2 . ASN B 2 61  ? 376.275 360.217 503.999 1.00 83.13  ? 61  ASN H ND2 1 
ATOM 1318 N N   . GLN B 2 62  ? 372.424 361.607 503.730 1.00 85.72  ? 62  GLN H N   1 
ATOM 1319 C CA  . GLN B 2 62  ? 371.495 361.875 504.822 1.00 85.72  ? 62  GLN H CA  1 
ATOM 1320 C C   . GLN B 2 62  ? 372.210 362.266 506.109 1.00 85.72  ? 62  GLN H C   1 
ATOM 1321 O O   . GLN B 2 62  ? 371.610 362.903 506.979 1.00 85.72  ? 62  GLN H O   1 
ATOM 1322 C CB  . GLN B 2 62  ? 370.614 360.652 505.059 1.00 85.72  ? 62  GLN H CB  1 
ATOM 1323 C CG  . GLN B 2 62  ? 369.257 360.965 505.657 1.00 85.72  ? 62  GLN H CG  1 
ATOM 1324 C CD  . GLN B 2 62  ? 368.290 361.543 504.646 1.00 85.72  ? 62  GLN H CD  1 
ATOM 1325 O OE1 . GLN B 2 62  ? 368.474 361.399 503.442 1.00 85.72  ? 62  GLN H OE1 1 
ATOM 1326 N NE2 . GLN B 2 62  ? 367.249 362.202 505.135 1.00 85.72  ? 62  GLN H NE2 1 
ATOM 1327 N N   . LYS B 2 63  ? 373.487 361.918 506.241 1.00 83.44  ? 63  LYS H N   1 
ATOM 1328 C CA  . LYS B 2 63  ? 374.230 362.241 507.450 1.00 83.44  ? 63  LYS H CA  1 
ATOM 1329 C C   . LYS B 2 63  ? 374.668 363.696 507.492 1.00 83.44  ? 63  LYS H C   1 
ATOM 1330 O O   . LYS B 2 63  ? 375.037 364.184 508.563 1.00 83.44  ? 63  LYS H O   1 
ATOM 1331 C CB  . LYS B 2 63  ? 375.460 361.339 507.578 1.00 83.44  ? 63  LYS H CB  1 
ATOM 1332 C CG  . LYS B 2 63  ? 375.261 360.059 508.384 1.00 83.44  ? 63  LYS H CG  1 
ATOM 1333 C CD  . LYS B 2 63  ? 374.285 359.097 507.723 1.00 83.44  ? 63  LYS H CD  1 
ATOM 1334 C CE  . LYS B 2 63  ? 374.692 357.651 507.911 1.00 83.44  ? 63  LYS H CE  1 
ATOM 1335 N NZ  . LYS B 2 63  ? 373.775 356.737 507.174 1.00 83.44  ? 63  LYS H NZ  1 
ATOM 1336 N N   . PHE B 2 64  ? 374.644 364.393 506.355 1.00 85.85  ? 64  PHE H N   1 
ATOM 1337 C CA  . PHE B 2 64  ? 375.091 365.778 506.267 1.00 85.85  ? 64  PHE H CA  1 
ATOM 1338 C C   . PHE B 2 64  ? 374.071 366.680 505.582 1.00 85.85  ? 64  PHE H C   1 
ATOM 1339 O O   . PHE B 2 64  ? 374.455 367.675 504.962 1.00 85.85  ? 64  PHE H O   1 
ATOM 1340 C CB  . PHE B 2 64  ? 376.426 365.858 505.529 1.00 85.85  ? 64  PHE H CB  1 
ATOM 1341 C CG  . PHE B 2 64  ? 377.488 364.978 506.102 1.00 85.85  ? 64  PHE H CG  1 
ATOM 1342 C CD1 . PHE B 2 64  ? 378.080 365.287 507.312 1.00 85.85  ? 64  PHE H CD1 1 
ATOM 1343 C CD2 . PHE B 2 64  ? 377.896 363.840 505.432 1.00 85.85  ? 64  PHE H CD2 1 
ATOM 1344 C CE1 . PHE B 2 64  ? 379.060 364.475 507.845 1.00 85.85  ? 64  PHE H CE1 1 
ATOM 1345 C CE2 . PHE B 2 64  ? 378.875 363.024 505.961 1.00 85.85  ? 64  PHE H CE2 1 
ATOM 1346 C CZ  . PHE B 2 64  ? 379.457 363.344 507.169 1.00 85.85  ? 64  PHE H CZ  1 
ATOM 1347 N N   . LYS B 2 65  ? 372.781 366.363 505.689 1.00 90.17  ? 65  LYS H N   1 
ATOM 1348 C CA  . LYS B 2 65  ? 371.784 367.060 504.885 1.00 90.17  ? 65  LYS H CA  1 
ATOM 1349 C C   . LYS B 2 65  ? 371.461 368.442 505.439 1.00 90.17  ? 65  LYS H C   1 
ATOM 1350 O O   . LYS B 2 65  ? 371.322 369.402 504.673 1.00 90.17  ? 65  LYS H O   1 
ATOM 1351 C CB  . LYS B 2 65  ? 370.514 366.218 504.787 1.00 90.17  ? 65  LYS H CB  1 
ATOM 1352 C CG  . LYS B 2 65  ? 369.418 366.851 503.951 1.00 90.17  ? 65  LYS H CG  1 
ATOM 1353 C CD  . LYS B 2 65  ? 368.281 365.887 503.688 1.00 90.17  ? 65  LYS H CD  1 
ATOM 1354 C CE  . LYS B 2 65  ? 368.759 364.681 502.905 1.00 90.17  ? 65  LYS H CE  1 
ATOM 1355 N NZ  . LYS B 2 65  ? 367.625 363.824 502.473 1.00 90.17  ? 65  LYS H NZ  1 
ATOM 1356 N N   . ASP B 2 66  ? 371.355 368.569 506.757 1.00 94.20  ? 66  ASP H N   1 
ATOM 1357 C CA  . ASP B 2 66  ? 370.832 369.779 507.376 1.00 94.20  ? 66  ASP H CA  1 
ATOM 1358 C C   . ASP B 2 66  ? 371.837 370.919 507.449 1.00 94.20  ? 66  ASP H C   1 
ATOM 1359 O O   . ASP B 2 66  ? 371.458 372.023 507.849 1.00 94.20  ? 66  ASP H O   1 
ATOM 1360 C CB  . ASP B 2 66  ? 370.324 369.468 508.787 1.00 94.20  ? 66  ASP H CB  1 
ATOM 1361 C CG  . ASP B 2 66  ? 368.984 368.763 508.784 1.00 94.20  ? 66  ASP H CG  1 
ATOM 1362 O OD1 . ASP B 2 66  ? 368.399 368.598 507.694 1.00 94.20  ? 66  ASP H OD1 1 
ATOM 1363 O OD2 . ASP B 2 66  ? 368.513 368.375 509.871 1.00 94.20  ? 66  ASP H OD2 1 
ATOM 1364 N N   . LYS B 2 67  ? 373.097 370.697 507.078 1.00 91.84  ? 67  LYS H N   1 
ATOM 1365 C CA  . LYS B 2 67  ? 374.136 371.700 507.279 1.00 91.84  ? 67  LYS H CA  1 
ATOM 1366 C C   . LYS B 2 67  ? 374.765 372.209 505.992 1.00 91.84  ? 67  LYS H C   1 
ATOM 1367 O O   . LYS B 2 67  ? 374.812 373.422 505.771 1.00 91.84  ? 67  LYS H O   1 
ATOM 1368 C CB  . LYS B 2 67  ? 375.225 371.134 508.197 1.00 91.84  ? 67  LYS H CB  1 
ATOM 1369 C CG  . LYS B 2 67  ? 374.714 370.778 509.578 1.00 91.84  ? 67  LYS H CG  1 
ATOM 1370 C CD  . LYS B 2 67  ? 375.855 370.441 510.511 1.00 91.84  ? 67  LYS H CD  1 
ATOM 1371 C CE  . LYS B 2 67  ? 375.332 369.862 511.797 1.00 91.84  ? 67  LYS H CE  1 
ATOM 1372 N NZ  . LYS B 2 67  ? 374.202 370.675 512.303 1.00 91.84  ? 67  LYS H NZ  1 
ATOM 1373 N N   . THR B 2 68  ? 375.252 371.318 505.133 1.00 87.97  ? 68  THR H N   1 
ATOM 1374 C CA  . THR B 2 68  ? 376.041 371.745 503.987 1.00 87.97  ? 68  THR H CA  1 
ATOM 1375 C C   . THR B 2 68  ? 375.159 372.318 502.885 1.00 87.97  ? 68  THR H C   1 
ATOM 1376 O O   . THR B 2 68  ? 374.025 371.888 502.665 1.00 87.97  ? 68  THR H O   1 
ATOM 1377 C CB  . THR B 2 68  ? 376.858 370.586 503.423 1.00 87.97  ? 68  THR H CB  1 
ATOM 1378 O OG1 . THR B 2 68  ? 375.983 369.500 503.104 1.00 87.97  ? 68  THR H OG1 1 
ATOM 1379 C CG2 . THR B 2 68  ? 377.880 370.120 504.432 1.00 87.97  ? 68  THR H CG2 1 
ATOM 1380 N N   . THR B 2 69  ? 375.705 373.311 502.188 1.00 84.80  ? 69  THR H N   1 
ATOM 1381 C CA  . THR B 2 69  ? 375.044 373.917 501.040 1.00 84.80  ? 69  THR H CA  1 
ATOM 1382 C C   . THR B 2 69  ? 376.079 374.089 499.943 1.00 84.80  ? 69  THR H C   1 
ATOM 1383 O O   . THR B 2 69  ? 376.934 374.972 500.037 1.00 84.80  ? 69  THR H O   1 
ATOM 1384 C CB  . THR B 2 69  ? 374.429 375.268 501.398 1.00 84.80  ? 69  THR H CB  1 
ATOM 1385 O OG1 . THR B 2 69  ? 375.358 376.019 502.186 1.00 84.80  ? 69  THR H OG1 1 
ATOM 1386 C CG2 . THR B 2 69  ? 373.132 375.093 502.173 1.00 84.80  ? 69  THR H CG2 1 
ATOM 1387 N N   . LEU B 2 70  ? 376.001 373.259 498.912 1.00 78.71  ? 70  LEU H N   1 
ATOM 1388 C CA  . LEU B 2 70  ? 376.935 373.301 497.796 1.00 78.71  ? 70  LEU H CA  1 
ATOM 1389 C C   . LEU B 2 70  ? 376.388 374.231 496.725 1.00 78.71  ? 70  LEU H C   1 
ATOM 1390 O O   . LEU B 2 70  ? 375.312 373.981 496.174 1.00 78.71  ? 70  LEU H O   1 
ATOM 1391 C CB  . LEU B 2 70  ? 377.157 371.908 497.217 1.00 78.71  ? 70  LEU H CB  1 
ATOM 1392 C CG  . LEU B 2 70  ? 377.256 370.751 498.200 1.00 78.71  ? 70  LEU H CG  1 
ATOM 1393 C CD1 . LEU B 2 70  ? 377.125 369.448 497.457 1.00 78.71  ? 70  LEU H CD1 1 
ATOM 1394 C CD2 . LEU B 2 70  ? 378.564 370.795 498.928 1.00 78.71  ? 70  LEU H CD2 1 
ATOM 1395 N N   . THR B 2 71  ? 377.119 375.299 496.435 1.00 80.81  ? 71  THR H N   1 
ATOM 1396 C CA  . THR B 2 71  ? 376.782 376.199 495.346 1.00 80.81  ? 71  THR H CA  1 
ATOM 1397 C C   . THR B 2 71  ? 377.892 376.164 494.307 1.00 80.81  ? 71  THR H C   1 
ATOM 1398 O O   . THR B 2 71  ? 378.952 375.570 494.516 1.00 80.81  ? 71  THR H O   1 
ATOM 1399 C CB  . THR B 2 71  ? 376.583 377.635 495.835 1.00 80.81  ? 71  THR H CB  1 
ATOM 1400 O OG1 . THR B 2 71  ? 377.857 378.278 495.937 1.00 80.81  ? 71  THR H OG1 1 
ATOM 1401 C CG2 . THR B 2 71  ? 375.909 377.658 497.195 1.00 80.81  ? 71  THR H CG2 1 
ATOM 1402 N N   . ALA B 2 72  ? 377.645 376.822 493.180 1.00 81.13  ? 72  ALA H N   1 
ATOM 1403 C CA  . ALA B 2 72  ? 378.633 376.909 492.116 1.00 81.13  ? 72  ALA H CA  1 
ATOM 1404 C C   . ALA B 2 72  ? 378.364 378.163 491.306 1.00 81.13  ? 72  ALA H C   1 
ATOM 1405 O O   . ALA B 2 72  ? 377.256 378.702 491.307 1.00 81.13  ? 72  ALA H O   1 
ATOM 1406 C CB  . ALA B 2 72  ? 378.606 375.675 491.216 1.00 81.13  ? 72  ALA H CB  1 
ATOM 1407 N N   . ASP B 2 73  ? 379.395 378.619 490.604 1.00 85.01  ? 73  ASP H N   1 
ATOM 1408 C CA  . ASP B 2 73  ? 379.261 379.762 489.718 1.00 85.01  ? 73  ASP H CA  1 
ATOM 1409 C C   . ASP B 2 73  ? 379.991 379.471 488.419 1.00 85.01  ? 73  ASP H C   1 
ATOM 1410 O O   . ASP B 2 73  ? 381.054 378.848 488.414 1.00 85.01  ? 73  ASP H O   1 
ATOM 1411 C CB  . ASP B 2 73  ? 379.788 381.047 490.361 1.00 85.01  ? 73  ASP H CB  1 
ATOM 1412 C CG  . ASP B 2 73  ? 381.236 380.947 490.755 1.00 85.01  ? 73  ASP H CG  1 
ATOM 1413 O OD1 . ASP B 2 73  ? 381.710 379.823 491.012 1.00 85.01  ? 73  ASP H OD1 1 
ATOM 1414 O OD2 . ASP B 2 73  ? 381.907 381.998 490.804 1.00 85.01  ? 73  ASP H OD2 1 
ATOM 1415 N N   . LYS B 2 74  ? 379.403 379.919 487.318 1.00 80.82  ? 74  LYS H N   1 
ATOM 1416 C CA  . LYS B 2 74  ? 379.903 379.563 485.999 1.00 80.82  ? 74  LYS H CA  1 
ATOM 1417 C C   . LYS B 2 74  ? 381.015 380.494 485.550 1.00 80.82  ? 74  LYS H C   1 
ATOM 1418 O O   . LYS B 2 74  ? 381.813 380.130 484.679 1.00 80.82  ? 74  LYS H O   1 
ATOM 1419 C CB  . LYS B 2 74  ? 378.764 379.598 484.979 1.00 80.82  ? 74  LYS H CB  1 
ATOM 1420 C CG  . LYS B 2 74  ? 377.840 378.397 485.004 1.00 80.82  ? 74  LYS H CG  1 
ATOM 1421 C CD  . LYS B 2 74  ? 376.750 378.527 486.057 1.00 80.82  ? 74  LYS H CD  1 
ATOM 1422 C CE  . LYS B 2 74  ? 375.701 377.467 485.899 1.00 80.82  ? 74  LYS H CE  1 
ATOM 1423 N NZ  . LYS B 2 74  ? 374.991 377.254 487.179 1.00 80.82  ? 74  LYS H NZ  1 
ATOM 1424 N N   . SER B 2 75  ? 381.069 381.693 486.127 1.00 85.27  ? 75  SER H N   1 
ATOM 1425 C CA  . SER B 2 75  ? 381.997 382.714 485.662 1.00 85.27  ? 75  SER H CA  1 
ATOM 1426 C C   . SER B 2 75  ? 383.426 382.381 486.061 1.00 85.27  ? 75  SER H C   1 
ATOM 1427 O O   . SER B 2 75  ? 384.294 382.177 485.206 1.00 85.27  ? 75  SER H O   1 
ATOM 1428 C CB  . SER B 2 75  ? 381.580 384.068 486.226 1.00 85.27  ? 75  SER H CB  1 
ATOM 1429 O OG  . SER B 2 75  ? 381.237 383.944 487.595 1.00 85.27  ? 75  SER H OG  1 
ATOM 1430 N N   . SER B 2 76  ? 383.687 382.306 487.363 1.00 85.87  ? 76  SER H N   1 
ATOM 1431 C CA  . SER B 2 76  ? 385.024 381.983 487.837 1.00 85.87  ? 76  SER H CA  1 
ATOM 1432 C C   . SER B 2 76  ? 385.317 380.490 487.817 1.00 85.87  ? 76  SER H C   1 
ATOM 1433 O O   . SER B 2 76  ? 386.450 380.108 488.130 1.00 85.87  ? 76  SER H O   1 
ATOM 1434 C CB  . SER B 2 76  ? 385.221 382.533 489.249 1.00 85.87  ? 76  SER H CB  1 
ATOM 1435 O OG  . SER B 2 76  ? 384.068 382.322 490.042 1.00 85.87  ? 76  SER H OG  1 
ATOM 1436 N N   . SER B 2 77  ? 384.327 379.664 487.448 1.00 81.93  ? 77  SER H N   1 
ATOM 1437 C CA  . SER B 2 77  ? 384.443 378.206 487.328 1.00 81.93  ? 77  SER H CA  1 
ATOM 1438 C C   . SER B 2 77  ? 384.882 377.560 488.637 1.00 81.93  ? 77  SER H C   1 
ATOM 1439 O O   . SER B 2 77  ? 385.746 376.686 488.660 1.00 81.93  ? 77  SER H O   1 
ATOM 1440 C CB  . SER B 2 77  ? 385.377 377.806 486.185 1.00 81.93  ? 77  SER H CB  1 
ATOM 1441 O OG  . SER B 2 77  ? 386.728 377.962 486.569 1.00 81.93  ? 77  SER H OG  1 
ATOM 1442 N N   . THR B 2 78  ? 384.288 378.000 489.737 1.00 82.01  ? 78  THR H N   1 
ATOM 1443 C CA  . THR B 2 78  ? 384.567 377.462 491.056 1.00 82.01  ? 78  THR H CA  1 
ATOM 1444 C C   . THR B 2 78  ? 383.330 376.775 491.618 1.00 82.01  ? 78  THR H C   1 
ATOM 1445 O O   . THR B 2 78  ? 382.246 376.814 491.035 1.00 82.01  ? 78  THR H O   1 
ATOM 1446 C CB  . THR B 2 78  ? 385.029 378.565 492.010 1.00 82.01  ? 78  THR H CB  1 
ATOM 1447 O OG1 . THR B 2 78  ? 383.903 379.360 492.383 1.00 82.01  ? 78  THR H OG1 1 
ATOM 1448 C CG2 . THR B 2 78  ? 386.070 379.453 491.362 1.00 82.01  ? 78  THR H CG2 1 
ATOM 1449 N N   . ALA B 2 79  ? 383.508 376.142 492.775 1.00 81.21  ? 79  ALA H N   1 
ATOM 1450 C CA  . ALA B 2 79  ? 382.432 375.434 493.463 1.00 81.21  ? 79  ALA H CA  1 
ATOM 1451 C C   . ALA B 2 79  ? 382.685 375.560 494.956 1.00 81.21  ? 79  ALA H C   1 
ATOM 1452 O O   . ALA B 2 79  ? 383.829 375.434 495.396 1.00 81.21  ? 79  ALA H O   1 
ATOM 1453 C CB  . ALA B 2 79  ? 382.375 373.971 493.037 1.00 81.21  ? 79  ALA H CB  1 
ATOM 1454 N N   . TYR B 2 80  ? 381.636 375.812 495.732 1.00 80.66  ? 80  TYR H N   1 
ATOM 1455 C CA  . TYR B 2 80  ? 381.804 376.083 497.150 1.00 80.66  ? 80  TYR H CA  1 
ATOM 1456 C C   . TYR B 2 80  ? 381.079 375.056 498.011 1.00 80.66  ? 80  TYR H C   1 
ATOM 1457 O O   . TYR B 2 80  ? 380.296 374.239 497.529 1.00 80.66  ? 80  TYR H O   1 
ATOM 1458 C CB  . TYR B 2 80  ? 381.292 377.478 497.491 1.00 80.66  ? 80  TYR H CB  1 
ATOM 1459 C CG  . TYR B 2 80  ? 381.793 378.563 496.581 1.00 80.66  ? 80  TYR H CG  1 
ATOM 1460 C CD1 . TYR B 2 80  ? 383.087 379.037 496.691 1.00 80.66  ? 80  TYR H CD1 1 
ATOM 1461 C CD2 . TYR B 2 80  ? 380.969 379.119 495.616 1.00 80.66  ? 80  TYR H CD2 1 
ATOM 1462 C CE1 . TYR B 2 80  ? 383.549 380.028 495.865 1.00 80.66  ? 80  TYR H CE1 1 
ATOM 1463 C CE2 . TYR B 2 80  ? 381.423 380.112 494.786 1.00 80.66  ? 80  TYR H CE2 1 
ATOM 1464 C CZ  . TYR B 2 80  ? 382.712 380.565 494.921 1.00 80.66  ? 80  TYR H CZ  1 
ATOM 1465 O OH  . TYR B 2 80  ? 383.179 381.553 494.093 1.00 80.66  ? 80  TYR H OH  1 
ATOM 1466 N N   . MET B 2 81  ? 381.344 375.125 499.315 1.00 86.21  ? 81  MET H N   1 
ATOM 1467 C CA  . MET B 2 81  ? 380.622 374.362 500.326 1.00 86.21  ? 81  MET H CA  1 
ATOM 1468 C C   . MET B 2 81  ? 380.630 375.162 501.615 1.00 86.21  ? 81  MET H C   1 
ATOM 1469 O O   . MET B 2 81  ? 381.688 375.632 502.038 1.00 86.21  ? 81  MET H O   1 
ATOM 1470 C CB  . MET B 2 81  ? 381.251 372.989 500.561 1.00 86.21  ? 81  MET H CB  1 
ATOM 1471 C CG  . MET B 2 81  ? 380.590 372.215 501.681 1.00 86.21  ? 81  MET H CG  1 
ATOM 1472 S SD  . MET B 2 81  ? 381.023 370.470 501.746 1.00 86.21  ? 81  MET H SD  1 
ATOM 1473 C CE  . MET B 2 81  ? 382.608 370.530 502.559 1.00 86.21  ? 81  MET H CE  1 
ATOM 1474 N N   . GLN B 2 82  ? 379.463 375.319 502.235 1.00 90.96  ? 82  GLN H N   1 
ATOM 1475 C CA  . GLN B 2 82  ? 379.326 376.106 503.454 1.00 90.96  ? 82  GLN H CA  1 
ATOM 1476 C C   . GLN B 2 82  ? 378.925 375.199 504.606 1.00 90.96  ? 82  GLN H C   1 
ATOM 1477 O O   . GLN B 2 82  ? 377.932 374.474 504.511 1.00 90.96  ? 82  GLN H O   1 
ATOM 1478 C CB  . GLN B 2 82  ? 378.298 377.220 503.277 1.00 90.96  ? 82  GLN H CB  1 
ATOM 1479 C CG  . GLN B 2 82  ? 377.959 377.943 504.556 1.00 90.96  ? 82  GLN H CG  1 
ATOM 1480 C CD  . GLN B 2 82  ? 376.986 379.068 504.333 1.00 90.96  ? 82  GLN H CD  1 
ATOM 1481 O OE1 . GLN B 2 82  ? 376.694 379.433 503.196 1.00 90.96  ? 82  GLN H OE1 1 
ATOM 1482 N NE2 . GLN B 2 82  ? 376.472 379.626 505.418 1.00 90.96  ? 82  GLN H NE2 1 
ATOM 1483 N N   . LEU B 2 83  ? 379.688 375.253 505.691 1.00 96.57  ? 83  LEU H N   1 
ATOM 1484 C CA  . LEU B 2 83  ? 379.428 374.450 506.876 1.00 96.57  ? 83  LEU H CA  1 
ATOM 1485 C C   . LEU B 2 83  ? 378.854 375.332 507.973 1.00 96.57  ? 83  LEU H C   1 
ATOM 1486 O O   . LEU B 2 83  ? 379.548 376.209 508.494 1.00 96.57  ? 83  LEU H O   1 
ATOM 1487 C CB  . LEU B 2 83  ? 380.710 373.782 507.371 1.00 96.57  ? 83  LEU H CB  1 
ATOM 1488 C CG  . LEU B 2 83  ? 381.507 372.954 506.370 1.00 96.57  ? 83  LEU H CG  1 
ATOM 1489 C CD1 . LEU B 2 83  ? 382.920 372.788 506.867 1.00 96.57  ? 83  LEU H CD1 1 
ATOM 1490 C CD2 . LEU B 2 83  ? 380.855 371.608 506.152 1.00 96.57  ? 83  LEU H CD2 1 
ATOM 1491 N N   . SER B 2 84  ? 377.598 375.096 508.328 1.00 99.85  ? 84  SER H N   1 
ATOM 1492 C CA  . SER B 2 84  ? 376.939 375.845 509.383 1.00 99.85  ? 84  SER H CA  1 
ATOM 1493 C C   . SER B 2 84  ? 376.851 374.986 510.634 1.00 99.85  ? 84  SER H C   1 
ATOM 1494 O O   . SER B 2 84  ? 376.793 373.755 510.548 1.00 99.85  ? 84  SER H O   1 
ATOM 1495 C CB  . SER B 2 84  ? 375.536 376.297 508.961 1.00 99.85  ? 84  SER H CB  1 
ATOM 1496 O OG  . SER B 2 84  ? 375.590 377.478 508.181 1.00 99.85  ? 84  SER H OG  1 
ATOM 1497 N N   . SER B 2 85  ? 376.846 375.662 511.790 1.00 103.19 ? 85  SER H N   1 
ATOM 1498 C CA  . SER B 2 85  ? 376.731 375.052 513.120 1.00 103.19 ? 85  SER H CA  1 
ATOM 1499 C C   . SER B 2 85  ? 377.847 374.036 513.369 1.00 103.19 ? 85  SER H C   1 
ATOM 1500 O O   . SER B 2 85  ? 377.618 372.828 513.454 1.00 103.19 ? 85  SER H O   1 
ATOM 1501 C CB  . SER B 2 85  ? 375.348 374.425 513.332 1.00 103.19 ? 85  SER H CB  1 
ATOM 1502 O OG  . SER B 2 85  ? 374.405 375.403 513.725 1.00 103.19 ? 85  SER H OG  1 
ATOM 1503 N N   . LEU B 2 86  ? 379.071 374.552 513.447 1.00 104.37 ? 86  LEU H N   1 
ATOM 1504 C CA  . LEU B 2 86  ? 380.232 373.710 513.697 1.00 104.37 ? 86  LEU H CA  1 
ATOM 1505 C C   . LEU B 2 86  ? 380.183 373.123 515.101 1.00 104.37 ? 86  LEU H C   1 
ATOM 1506 O O   . LEU B 2 86  ? 379.692 373.759 516.039 1.00 104.37 ? 86  LEU H O   1 
ATOM 1507 C CB  . LEU B 2 86  ? 381.517 374.511 513.518 1.00 104.37 ? 86  LEU H CB  1 
ATOM 1508 C CG  . LEU B 2 86  ? 381.737 375.188 512.170 1.00 104.37 ? 86  LEU H CG  1 
ATOM 1509 C CD1 . LEU B 2 86  ? 382.506 376.480 512.355 1.00 104.37 ? 86  LEU H CD1 1 
ATOM 1510 C CD2 . LEU B 2 86  ? 382.476 374.260 511.229 1.00 104.37 ? 86  LEU H CD2 1 
ATOM 1511 N N   . THR B 2 87  ? 380.680 371.900 515.234 1.00 106.48 ? 87  THR H N   1 
ATOM 1512 C CA  . THR B 2 87  ? 380.807 371.189 516.496 1.00 106.48 ? 87  THR H CA  1 
ATOM 1513 C C   . THR B 2 87  ? 382.226 370.605 516.512 1.00 106.48 ? 87  THR H C   1 
ATOM 1514 O O   . THR B 2 87  ? 382.978 370.755 515.548 1.00 106.48 ? 87  THR H O   1 
ATOM 1515 C CB  . THR B 2 87  ? 379.687 370.143 516.610 1.00 106.48 ? 87  THR H CB  1 
ATOM 1516 O OG1 . THR B 2 87  ? 378.475 370.706 516.098 1.00 106.48 ? 87  THR H OG1 1 
ATOM 1517 C CG2 . THR B 2 87  ? 379.391 369.764 518.066 1.00 106.48 ? 87  THR H CG2 1 
ATOM 1518 N N   . PHE B 2 88  ? 382.601 369.948 517.613 1.00 109.73 ? 88  PHE H N   1 
ATOM 1519 C CA  . PHE B 2 88  ? 383.934 369.370 517.745 1.00 109.73 ? 88  PHE H CA  1 
ATOM 1520 C C   . PHE B 2 88  ? 384.171 368.189 516.810 1.00 109.73 ? 88  PHE H C   1 
ATOM 1521 O O   . PHE B 2 88  ? 385.329 367.833 516.570 1.00 109.73 ? 88  PHE H O   1 
ATOM 1522 C CB  . PHE B 2 88  ? 384.180 368.924 519.189 1.00 109.73 ? 88  PHE H CB  1 
ATOM 1523 C CG  . PHE B 2 88  ? 384.718 370.008 520.085 1.00 109.73 ? 88  PHE H CG  1 
ATOM 1524 C CD1 . PHE B 2 88  ? 384.681 371.338 519.698 1.00 109.73 ? 88  PHE H CD1 1 
ATOM 1525 C CD2 . PHE B 2 88  ? 385.257 369.690 521.321 1.00 109.73 ? 88  PHE H CD2 1 
ATOM 1526 C CE1 . PHE B 2 88  ? 385.173 372.333 520.527 1.00 109.73 ? 88  PHE H CE1 1 
ATOM 1527 C CE2 . PHE B 2 88  ? 385.754 370.678 522.156 1.00 109.73 ? 88  PHE H CE2 1 
ATOM 1528 C CZ  . PHE B 2 88  ? 385.711 372.001 521.758 1.00 109.73 ? 88  PHE H CZ  1 
ATOM 1529 N N   . GLU B 2 89  ? 383.113 367.580 516.279 1.00 106.56 ? 89  GLU H N   1 
ATOM 1530 C CA  . GLU B 2 89  ? 383.240 366.491 515.324 1.00 106.56 ? 89  GLU H CA  1 
ATOM 1531 C C   . GLU B 2 89  ? 383.444 366.979 513.897 1.00 106.56 ? 89  GLU H C   1 
ATOM 1532 O O   . GLU B 2 89  ? 383.722 366.167 513.010 1.00 106.56 ? 89  GLU H O   1 
ATOM 1533 C CB  . GLU B 2 89  ? 382.009 365.590 515.388 1.00 106.56 ? 89  GLU H CB  1 
ATOM 1534 C CG  . GLU B 2 89  ? 381.809 364.948 516.741 1.00 106.56 ? 89  GLU H CG  1 
ATOM 1535 C CD  . GLU B 2 89  ? 382.271 363.507 516.773 1.00 106.56 ? 89  GLU H CD  1 
ATOM 1536 O OE1 . GLU B 2 89  ? 382.857 363.049 515.770 1.00 106.56 ? 89  GLU H OE1 1 
ATOM 1537 O OE2 . GLU B 2 89  ? 382.051 362.839 517.805 1.00 106.56 ? 89  GLU H OE2 1 
ATOM 1538 N N   . ASP B 2 90  ? 383.325 368.281 513.657 1.00 103.78 ? 90  ASP H N   1 
ATOM 1539 C CA  . ASP B 2 90  ? 383.471 368.844 512.325 1.00 103.78 ? 90  ASP H CA  1 
ATOM 1540 C C   . ASP B 2 90  ? 384.891 369.305 512.036 1.00 103.78 ? 90  ASP H C   1 
ATOM 1541 O O   . ASP B 2 90  ? 385.082 370.252 511.266 1.00 103.78 ? 90  ASP H O   1 
ATOM 1542 C CB  . ASP B 2 90  ? 382.496 370.004 512.137 1.00 103.78 ? 90  ASP H CB  1 
ATOM 1543 C CG  . ASP B 2 90  ? 382.008 370.124 510.716 1.00 103.78 ? 90  ASP H CG  1 
ATOM 1544 O OD1 . ASP B 2 90  ? 382.342 369.241 509.902 1.00 103.78 ? 90  ASP H OD1 1 
ATOM 1545 O OD2 . ASP B 2 90  ? 381.293 371.100 510.414 1.00 103.78 ? 90  ASP H OD2 1 
ATOM 1546 N N   . SER B 2 91  ? 385.886 368.673 512.646 1.00 104.80 ? 91  SER H N   1 
ATOM 1547 C CA  . SER B 2 91  ? 387.286 368.975 512.377 1.00 104.80 ? 91  SER H CA  1 
ATOM 1548 C C   . SER B 2 91  ? 387.861 367.841 511.542 1.00 104.80 ? 91  SER H C   1 
ATOM 1549 O O   . SER B 2 91  ? 388.113 366.751 512.061 1.00 104.80 ? 91  SER H O   1 
ATOM 1550 C CB  . SER B 2 91  ? 388.058 369.145 513.680 1.00 104.80 ? 91  SER H CB  1 
ATOM 1551 O OG  . SER B 2 91  ? 387.703 368.133 514.604 1.00 104.80 ? 91  SER H OG  1 
ATOM 1552 N N   . ALA B 2 92  ? 388.074 368.094 510.257 1.00 95.33  ? 92  ALA H N   1 
ATOM 1553 C CA  . ALA B 2 92  ? 388.479 367.040 509.338 1.00 95.33  ? 92  ALA H CA  1 
ATOM 1554 C C   . ALA B 2 92  ? 389.228 367.667 508.169 1.00 95.33  ? 92  ALA H C   1 
ATOM 1555 O O   . ALA B 2 92  ? 389.576 368.851 508.195 1.00 95.33  ? 92  ALA H O   1 
ATOM 1556 C CB  . ALA B 2 92  ? 387.261 366.242 508.869 1.00 95.33  ? 92  ALA H CB  1 
ATOM 1557 N N   . VAL B 2 93  ? 389.484 366.864 507.143 1.00 88.89  ? 93  VAL H N   1 
ATOM 1558 C CA  . VAL B 2 93  ? 390.066 367.327 505.891 1.00 88.89  ? 93  VAL H CA  1 
ATOM 1559 C C   . VAL B 2 93  ? 389.030 367.098 504.804 1.00 88.89  ? 93  VAL H C   1 
ATOM 1560 O O   . VAL B 2 93  ? 388.459 366.007 504.710 1.00 88.89  ? 93  VAL H O   1 
ATOM 1561 C CB  . VAL B 2 93  ? 391.385 366.597 505.580 1.00 88.89  ? 93  VAL H CB  1 
ATOM 1562 C CG1 . VAL B 2 93  ? 391.865 366.903 504.176 1.00 88.89  ? 93  VAL H CG1 1 
ATOM 1563 C CG2 . VAL B 2 93  ? 392.448 366.985 506.582 1.00 88.89  ? 93  VAL H CG2 1 
ATOM 1564 N N   . TYR B 2 94  ? 388.767 368.127 504.005 1.00 86.13  ? 94  TYR H N   1 
ATOM 1565 C CA  . TYR B 2 94  ? 387.730 368.091 502.985 1.00 86.13  ? 94  TYR H CA  1 
ATOM 1566 C C   . TYR B 2 94  ? 388.375 368.095 501.607 1.00 86.13  ? 94  TYR H C   1 
ATOM 1567 O O   . TYR B 2 94  ? 389.219 368.946 501.321 1.00 86.13  ? 94  TYR H O   1 
ATOM 1568 C CB  . TYR B 2 94  ? 386.791 369.283 503.133 1.00 86.13  ? 94  TYR H CB  1 
ATOM 1569 C CG  . TYR B 2 94  ? 385.983 369.269 504.398 1.00 86.13  ? 94  TYR H CG  1 
ATOM 1570 C CD1 . TYR B 2 94  ? 384.914 368.407 504.546 1.00 86.13  ? 94  TYR H CD1 1 
ATOM 1571 C CD2 . TYR B 2 94  ? 386.287 370.124 505.445 1.00 86.13  ? 94  TYR H CD2 1 
ATOM 1572 C CE1 . TYR B 2 94  ? 384.169 368.394 505.704 1.00 86.13  ? 94  TYR H CE1 1 
ATOM 1573 C CE2 . TYR B 2 94  ? 385.548 370.116 506.609 1.00 86.13  ? 94  TYR H CE2 1 
ATOM 1574 C CZ  . TYR B 2 94  ? 384.492 369.249 506.729 1.00 86.13  ? 94  TYR H CZ  1 
ATOM 1575 O OH  . TYR B 2 94  ? 383.748 369.233 507.878 1.00 86.13  ? 94  TYR H OH  1 
ATOM 1576 N N   . TYR B 2 95  ? 387.969 367.159 500.759 1.00 79.97  ? 95  TYR H N   1 
ATOM 1577 C CA  . TYR B 2 95  ? 388.418 367.089 499.379 1.00 79.97  ? 95  TYR H CA  1 
ATOM 1578 C C   . TYR B 2 95  ? 387.261 367.406 498.442 1.00 79.97  ? 95  TYR H C   1 
ATOM 1579 O O   . TYR B 2 95  ? 386.091 367.325 498.820 1.00 79.97  ? 95  TYR H O   1 
ATOM 1580 C CB  . TYR B 2 95  ? 388.964 365.698 499.039 1.00 79.97  ? 95  TYR H CB  1 
ATOM 1581 C CG  . TYR B 2 95  ? 390.179 365.261 499.816 1.00 79.97  ? 95  TYR H CG  1 
ATOM 1582 C CD1 . TYR B 2 95  ? 390.050 364.646 501.050 1.00 79.97  ? 95  TYR H CD1 1 
ATOM 1583 C CD2 . TYR B 2 95  ? 391.452 365.435 499.301 1.00 79.97  ? 95  TYR H CD2 1 
ATOM 1584 C CE1 . TYR B 2 95  ? 391.154 364.239 501.757 1.00 79.97  ? 95  TYR H CE1 1 
ATOM 1585 C CE2 . TYR B 2 95  ? 392.563 365.028 500.000 1.00 79.97  ? 95  TYR H CE2 1 
ATOM 1586 C CZ  . TYR B 2 95  ? 392.406 364.433 501.228 1.00 79.97  ? 95  TYR H CZ  1 
ATOM 1587 O OH  . TYR B 2 95  ? 393.511 364.024 501.932 1.00 79.97  ? 95  TYR H OH  1 
ATOM 1588 N N   . CYS B 2 96  ? 387.597 367.759 497.207 1.00 79.14  ? 96  CYS H N   1 
ATOM 1589 C CA  . CYS B 2 96  ? 386.626 367.844 496.127 1.00 79.14  ? 96  CYS H CA  1 
ATOM 1590 C C   . CYS B 2 96  ? 387.090 366.941 495.000 1.00 79.14  ? 96  CYS H C   1 
ATOM 1591 O O   . CYS B 2 96  ? 388.263 366.969 494.622 1.00 79.14  ? 96  CYS H O   1 
ATOM 1592 C CB  . CYS B 2 96  ? 386.443 369.278 495.624 1.00 79.14  ? 96  CYS H CB  1 
ATOM 1593 S SG  . CYS B 2 96  ? 387.961 370.158 495.219 1.00 79.14  ? 96  CYS H SG  1 
ATOM 1594 N N   . ALA B 2 97  ? 386.178 366.132 494.477 1.00 71.04  ? 97  ALA H N   1 
ATOM 1595 C CA  . ALA B 2 97  ? 386.488 365.204 493.406 1.00 71.04  ? 97  ALA H CA  1 
ATOM 1596 C C   . ALA B 2 97  ? 385.659 365.556 492.186 1.00 71.04  ? 97  ALA H C   1 
ATOM 1597 O O   . ALA B 2 97  ? 384.798 366.434 492.230 1.00 71.04  ? 97  ALA H O   1 
ATOM 1598 C CB  . ALA B 2 97  ? 386.216 363.756 493.813 1.00 71.04  ? 97  ALA H CB  1 
ATOM 1599 N N   . ARG B 2 98  ? 385.926 364.856 491.093 1.00 66.28  ? 98  ARG H N   1 
ATOM 1600 C CA  . ARG B 2 98  ? 385.188 365.012 489.847 1.00 66.28  ? 98  ARG H CA  1 
ATOM 1601 C C   . ARG B 2 98  ? 384.792 363.626 489.373 1.00 66.28  ? 98  ARG H C   1 
ATOM 1602 O O   . ARG B 2 98  ? 385.595 362.940 488.734 1.00 66.28  ? 98  ARG H O   1 
ATOM 1603 C CB  . ARG B 2 98  ? 386.033 365.722 488.799 1.00 66.28  ? 98  ARG H CB  1 
ATOM 1604 C CG  . ARG B 2 98  ? 385.304 366.051 487.528 1.00 66.28  ? 98  ARG H CG  1 
ATOM 1605 C CD  . ARG B 2 98  ? 386.290 366.462 486.475 1.00 66.28  ? 98  ARG H CD  1 
ATOM 1606 N NE  . ARG B 2 98  ? 387.003 365.298 485.979 1.00 66.28  ? 98  ARG H NE  1 
ATOM 1607 C CZ  . ARG B 2 98  ? 387.049 364.944 484.703 1.00 66.28  ? 98  ARG H CZ  1 
ATOM 1608 N NH1 . ARG B 2 98  ? 386.441 365.684 483.795 1.00 66.28  ? 98  ARG H NH1 1 
ATOM 1609 N NH2 . ARG B 2 98  ? 387.712 363.861 484.336 1.00 66.28  ? 98  ARG H NH2 1 
ATOM 1610 N N   . ARG B 2 99  ? 383.569 363.214 489.695 1.00 66.77  ? 99  ARG H N   1 
ATOM 1611 C CA  . ARG B 2 99  ? 383.080 361.887 489.348 1.00 66.77  ? 99  ARG H CA  1 
ATOM 1612 C C   . ARG B 2 99  ? 382.906 361.781 487.841 1.00 66.77  ? 99  ARG H C   1 
ATOM 1613 O O   . ARG B 2 99  ? 382.249 362.619 487.220 1.00 66.77  ? 99  ARG H O   1 
ATOM 1614 C CB  . ARG B 2 99  ? 381.758 361.582 490.052 1.00 66.77  ? 99  ARG H CB  1 
ATOM 1615 C CG  . ARG B 2 99  ? 380.923 360.526 489.355 1.00 66.77  ? 99  ARG H CG  1 
ATOM 1616 C CD  . ARG B 2 99  ? 379.784 360.008 490.213 1.00 66.77  ? 99  ARG H CD  1 
ATOM 1617 N NE  . ARG B 2 99  ? 378.573 360.817 490.119 1.00 66.77  ? 99  ARG H NE  1 
ATOM 1618 C CZ  . ARG B 2 99  ? 377.704 360.765 489.116 1.00 66.77  ? 99  ARG H CZ  1 
ATOM 1619 N NH1 . ARG B 2 99  ? 377.900 359.948 488.099 1.00 66.77  ? 99  ARG H NH1 1 
ATOM 1620 N NH2 . ARG B 2 99  ? 376.630 361.536 489.129 1.00 66.77  ? 99  ARG H NH2 1 
ATOM 1621 N N   . SER B 2 100 ? 383.519 360.767 487.258 1.00 65.81  ? 100 SER H N   1 
ATOM 1622 C CA  . SER B 2 100 ? 383.396 360.510 485.841 1.00 65.81  ? 100 SER H CA  1 
ATOM 1623 C C   . SER B 2 100 ? 383.219 359.015 485.640 1.00 65.81  ? 100 SER H C   1 
ATOM 1624 O O   . SER B 2 100 ? 383.675 358.214 486.458 1.00 65.81  ? 100 SER H O   1 
ATOM 1625 C CB  . SER B 2 100 ? 384.611 361.024 485.092 1.00 65.81  ? 100 SER H CB  1 
ATOM 1626 O OG  . SER B 2 100 ? 385.593 360.014 485.004 1.00 65.81  ? 100 SER H OG  1 
ATOM 1627 N N   . GLU B 2 101 ? 382.526 358.658 484.553 1.00 65.01  ? 101 GLU H N   1 
ATOM 1628 C CA  . GLU B 2 101 ? 382.111 357.286 484.231 1.00 65.01  ? 101 GLU H CA  1 
ATOM 1629 C C   . GLU B 2 101 ? 381.275 356.647 485.339 1.00 65.01  ? 101 GLU H C   1 
ATOM 1630 O O   . GLU B 2 101 ? 381.363 355.440 485.563 1.00 65.01  ? 101 GLU H O   1 
ATOM 1631 C CB  . GLU B 2 101 ? 383.301 356.387 483.884 1.00 65.01  ? 101 GLU H CB  1 
ATOM 1632 C CG  . GLU B 2 101 ? 383.823 356.509 482.471 1.00 65.01  ? 101 GLU H CG  1 
ATOM 1633 C CD  . GLU B 2 101 ? 384.846 357.610 482.273 1.00 65.01  ? 101 GLU H CD  1 
ATOM 1634 O OE1 . GLU B 2 101 ? 385.565 357.574 481.254 1.00 65.01  ? 101 GLU H OE1 1 
ATOM 1635 O OE2 . GLU B 2 101 ? 384.960 358.498 483.131 1.00 65.01  ? 101 GLU H OE2 1 
ATOM 1636 N N   . ALA B 2 102 ? 380.512 357.479 486.054 1.00 65.94  ? 102 ALA H N   1 
ATOM 1637 C CA  . ALA B 2 102 ? 379.407 357.159 486.961 1.00 65.94  ? 102 ALA H CA  1 
ATOM 1638 C C   . ALA B 2 102 ? 379.798 356.536 488.295 1.00 65.94  ? 102 ALA H C   1 
ATOM 1639 O O   . ALA B 2 102 ? 378.947 356.415 489.180 1.00 65.94  ? 102 ALA H O   1 
ATOM 1640 C CB  . ALA B 2 102 ? 378.382 356.248 486.279 1.00 65.94  ? 102 ALA H CB  1 
ATOM 1641 N N   . ASP B 2 103 ? 381.052 356.129 488.468 1.00 70.68  ? 103 ASP H N   1 
ATOM 1642 C CA  . ASP B 2 103 ? 381.518 355.750 489.799 1.00 70.68  ? 103 ASP H CA  1 
ATOM 1643 C C   . ASP B 2 103 ? 382.945 356.161 490.108 1.00 70.68  ? 103 ASP H C   1 
ATOM 1644 O O   . ASP B 2 103 ? 383.328 356.125 491.280 1.00 70.68  ? 103 ASP H O   1 
ATOM 1645 C CB  . ASP B 2 103 ? 381.377 354.238 490.010 1.00 70.68  ? 103 ASP H CB  1 
ATOM 1646 C CG  . ASP B 2 103 ? 381.765 353.436 488.786 1.00 70.68  ? 103 ASP H CG  1 
ATOM 1647 O OD1 . ASP B 2 103 ? 382.326 354.025 487.847 1.00 70.68  ? 103 ASP H OD1 1 
ATOM 1648 O OD2 . ASP B 2 103 ? 381.501 352.218 488.757 1.00 70.68  ? 103 ASP H OD2 1 
ATOM 1649 N N   . ARG B 2 104 ? 383.742 356.551 489.125 1.00 68.23  ? 104 ARG H N   1 
ATOM 1650 C CA  . ARG B 2 104 ? 385.183 356.669 489.281 1.00 68.23  ? 104 ARG H CA  1 
ATOM 1651 C C   . ARG B 2 104 ? 385.596 358.112 489.513 1.00 68.23  ? 104 ARG H C   1 
ATOM 1652 O O   . ARG B 2 104 ? 385.362 358.977 488.669 1.00 68.23  ? 104 ARG H O   1 
ATOM 1653 C CB  . ARG B 2 104 ? 385.876 356.147 488.029 1.00 68.23  ? 104 ARG H CB  1 
ATOM 1654 C CG  . ARG B 2 104 ? 385.549 354.725 487.667 1.00 68.23  ? 104 ARG H CG  1 
ATOM 1655 C CD  . ARG B 2 104 ? 385.876 354.522 486.218 1.00 68.23  ? 104 ARG H CD  1 
ATOM 1656 N NE  . ARG B 2 104 ? 385.766 353.141 485.776 1.00 68.23  ? 104 ARG H NE  1 
ATOM 1657 C CZ  . ARG B 2 104 ? 384.675 352.597 485.258 1.00 68.23  ? 104 ARG H CZ  1 
ATOM 1658 N NH1 . ARG B 2 104 ? 383.575 353.311 485.130 1.00 68.23  ? 104 ARG H NH1 1 
ATOM 1659 N NH2 . ARG B 2 104 ? 384.680 351.330 484.873 1.00 68.23  ? 104 ARG H NH2 1 
ATOM 1660 N N   . PHE B 2 105 ? 386.244 358.367 490.637 1.00 67.65  ? 105 PHE H N   1 
ATOM 1661 C CA  . PHE B 2 105 ? 386.747 359.698 490.952 1.00 67.65  ? 105 PHE H CA  1 
ATOM 1662 C C   . PHE B 2 105 ? 388.159 359.800 490.394 1.00 67.65  ? 105 PHE H C   1 
ATOM 1663 O O   . PHE B 2 105 ? 389.116 359.356 491.030 1.00 67.65  ? 105 PHE H O   1 
ATOM 1664 C CB  . PHE B 2 105 ? 386.729 359.952 492.451 1.00 67.65  ? 105 PHE H CB  1 
ATOM 1665 C CG  . PHE B 2 105 ? 385.377 359.833 493.066 1.00 67.65  ? 105 PHE H CG  1 
ATOM 1666 C CD1 . PHE B 2 105 ? 384.365 360.691 492.703 1.00 67.65  ? 105 PHE H CD1 1 
ATOM 1667 C CD2 . PHE B 2 105 ? 385.122 358.869 494.017 1.00 67.65  ? 105 PHE H CD2 1 
ATOM 1668 C CE1 . PHE B 2 105 ? 383.117 360.586 493.275 1.00 67.65  ? 105 PHE H CE1 1 
ATOM 1669 C CE2 . PHE B 2 105 ? 383.876 358.760 494.591 1.00 67.65  ? 105 PHE H CE2 1 
ATOM 1670 C CZ  . PHE B 2 105 ? 382.874 359.621 494.218 1.00 67.65  ? 105 PHE H CZ  1 
ATOM 1671 N N   . VAL B 2 106 ? 388.292 360.406 489.217 1.00 66.62  ? 106 VAL H N   1 
ATOM 1672 C CA  . VAL B 2 106 ? 389.580 360.413 488.536 1.00 66.62  ? 106 VAL H CA  1 
ATOM 1673 C C   . VAL B 2 106 ? 390.480 361.516 489.073 1.00 66.62  ? 106 VAL H C   1 
ATOM 1674 O O   . VAL B 2 106 ? 391.661 361.286 489.355 1.00 66.62  ? 106 VAL H O   1 
ATOM 1675 C CB  . VAL B 2 106 ? 389.375 360.539 487.020 1.00 66.62  ? 106 VAL H CB  1 
ATOM 1676 C CG1 . VAL B 2 106 ? 390.701 360.494 486.311 1.00 66.62  ? 106 VAL H CG1 1 
ATOM 1677 C CG2 . VAL B 2 106 ? 388.501 359.423 486.532 1.00 66.62  ? 106 VAL H CG2 1 
ATOM 1678 N N   . TYR B 2 107 ? 389.950 362.724 489.229 1.00 66.76  ? 107 TYR H N   1 
ATOM 1679 C CA  . TYR B 2 107 ? 390.743 363.870 489.648 1.00 66.76  ? 107 TYR H CA  1 
ATOM 1680 C C   . TYR B 2 107 ? 390.295 364.341 491.021 1.00 66.76  ? 107 TYR H C   1 
ATOM 1681 O O   . TYR B 2 107 ? 389.101 364.534 491.255 1.00 66.76  ? 107 TYR H O   1 
ATOM 1682 C CB  . TYR B 2 107 ? 390.632 365.005 488.633 1.00 66.76  ? 107 TYR H CB  1 
ATOM 1683 C CG  . TYR B 2 107 ? 391.123 364.618 487.264 1.00 66.76  ? 107 TYR H CG  1 
ATOM 1684 C CD1 . TYR B 2 107 ? 392.281 363.873 487.110 1.00 66.76  ? 107 TYR H CD1 1 
ATOM 1685 C CD2 . TYR B 2 107 ? 390.424 364.983 486.128 1.00 66.76  ? 107 TYR H CD2 1 
ATOM 1686 C CE1 . TYR B 2 107 ? 392.733 363.510 485.860 1.00 66.76  ? 107 TYR H CE1 1 
ATOM 1687 C CE2 . TYR B 2 107 ? 390.869 364.625 484.877 1.00 66.76  ? 107 TYR H CE2 1 
ATOM 1688 C CZ  . TYR B 2 107 ? 392.021 363.888 484.750 1.00 66.76  ? 107 TYR H CZ  1 
ATOM 1689 O OH  . TYR B 2 107 ? 392.464 363.530 483.503 1.00 66.76  ? 107 TYR H OH  1 
ATOM 1690 N N   . TRP B 2 108 ? 391.255 364.536 491.915 1.00 69.77  ? 108 TRP H N   1 
ATOM 1691 C CA  . TRP B 2 108 ? 391.005 364.984 493.274 1.00 69.77  ? 108 TRP H CA  1 
ATOM 1692 C C   . TRP B 2 108 ? 391.701 366.313 493.517 1.00 69.77  ? 108 TRP H C   1 
ATOM 1693 O O   . TRP B 2 108 ? 392.550 366.751 492.740 1.00 69.77  ? 108 TRP H O   1 
ATOM 1694 C CB  . TRP B 2 108 ? 391.502 363.958 494.295 1.00 69.77  ? 108 TRP H CB  1 
ATOM 1695 C CG  . TRP B 2 108 ? 390.718 362.704 494.346 1.00 69.77  ? 108 TRP H CG  1 
ATOM 1696 C CD1 . TRP B 2 108 ? 390.617 361.760 493.375 1.00 69.77  ? 108 TRP H CD1 1 
ATOM 1697 C CD2 . TRP B 2 108 ? 389.933 362.240 495.441 1.00 69.77  ? 108 TRP H CD2 1 
ATOM 1698 N NE1 . TRP B 2 108 ? 389.809 360.737 493.792 1.00 69.77  ? 108 TRP H NE1 1 
ATOM 1699 C CE2 . TRP B 2 108 ? 389.375 361.011 495.061 1.00 69.77  ? 108 TRP H CE2 1 
ATOM 1700 C CE3 . TRP B 2 108 ? 389.640 362.751 496.702 1.00 69.77  ? 108 TRP H CE3 1 
ATOM 1701 C CZ2 . TRP B 2 108 ? 388.544 360.284 495.898 1.00 69.77  ? 108 TRP H CZ2 1 
ATOM 1702 C CZ3 . TRP B 2 108 ? 388.816 362.029 497.529 1.00 69.77  ? 108 TRP H CZ3 1 
ATOM 1703 C CH2 . TRP B 2 108 ? 388.277 360.809 497.126 1.00 69.77  ? 108 TRP H CH2 1 
ATOM 1704 N N   . GLY B 2 109 ? 391.335 366.953 494.627 1.00 76.72  ? 109 GLY H N   1 
ATOM 1705 C CA  . GLY B 2 109 ? 391.998 368.153 495.079 1.00 76.72  ? 109 GLY H CA  1 
ATOM 1706 C C   . GLY B 2 109 ? 393.091 367.841 496.091 1.00 76.72  ? 109 GLY H C   1 
ATOM 1707 O O   . GLY B 2 109 ? 393.429 366.692 496.358 1.00 76.72  ? 109 GLY H O   1 
ATOM 1708 N N   . GLN B 2 110 ? 393.652 368.906 496.658 1.00 82.59  ? 110 GLN H N   1 
ATOM 1709 C CA  . GLN B 2 110 ? 394.711 368.751 497.644 1.00 82.59  ? 110 GLN H CA  1 
ATOM 1710 C C   . GLN B 2 110 ? 394.200 368.744 499.075 1.00 82.59  ? 110 GLN H C   1 
ATOM 1711 O O   . GLN B 2 110 ? 394.952 368.375 499.981 1.00 82.59  ? 110 GLN H O   1 
ATOM 1712 C CB  . GLN B 2 110 ? 395.755 369.856 497.485 1.00 82.59  ? 110 GLN H CB  1 
ATOM 1713 C CG  . GLN B 2 110 ? 395.310 371.203 497.995 1.00 82.59  ? 110 GLN H CG  1 
ATOM 1714 C CD  . GLN B 2 110 ? 394.764 372.073 496.897 1.00 82.59  ? 110 GLN H CD  1 
ATOM 1715 O OE1 . GLN B 2 110 ? 394.625 371.633 495.759 1.00 82.59  ? 110 GLN H OE1 1 
ATOM 1716 N NE2 . GLN B 2 110 ? 394.460 373.320 497.225 1.00 82.59  ? 110 GLN H NE2 1 
ATOM 1717 N N   . GLY B 2 111 ? 392.957 369.142 499.307 1.00 86.50  ? 111 GLY H N   1 
ATOM 1718 C CA  . GLY B 2 111 ? 392.396 369.054 500.636 1.00 86.50  ? 111 GLY H CA  1 
ATOM 1719 C C   . GLY B 2 111 ? 392.679 370.254 501.511 1.00 86.50  ? 111 GLY H C   1 
ATOM 1720 O O   . GLY B 2 111 ? 393.809 370.747 501.550 1.00 86.50  ? 111 GLY H O   1 
ATOM 1721 N N   . THR B 2 112 ? 391.657 370.741 502.209 1.00 92.01  ? 112 THR H N   1 
ATOM 1722 C CA  . THR B 2 112 ? 391.797 371.837 503.156 1.00 92.01  ? 112 THR H CA  1 
ATOM 1723 C C   . THR B 2 112 ? 391.450 371.353 504.554 1.00 92.01  ? 112 THR H C   1 
ATOM 1724 O O   . THR B 2 112 ? 390.450 370.657 504.750 1.00 92.01  ? 112 THR H O   1 
ATOM 1725 C CB  . THR B 2 112 ? 390.894 373.018 502.799 1.00 92.01  ? 112 THR H CB  1 
ATOM 1726 O OG1 . THR B 2 112 ? 389.555 372.736 503.216 1.00 92.01  ? 112 THR H OG1 1 
ATOM 1727 C CG2 . THR B 2 112 ? 390.910 373.280 501.316 1.00 92.01  ? 112 THR H CG2 1 
ATOM 1728 N N   . LEU B 2 113 ? 392.268 371.739 505.524 1.00 98.31  ? 113 LEU H N   1 
ATOM 1729 C CA  . LEU B 2 113 ? 392.094 371.329 506.909 1.00 98.31  ? 113 LEU H CA  1 
ATOM 1730 C C   . LEU B 2 113 ? 391.265 372.373 507.644 1.00 98.31  ? 113 LEU H C   1 
ATOM 1731 O O   . LEU B 2 113 ? 391.683 373.527 507.769 1.00 98.31  ? 113 LEU H O   1 
ATOM 1732 C CB  . LEU B 2 113 ? 393.449 371.150 507.588 1.00 98.31  ? 113 LEU H CB  1 
ATOM 1733 C CG  . LEU B 2 113 ? 393.407 370.940 509.097 1.00 98.31  ? 113 LEU H CG  1 
ATOM 1734 C CD1 . LEU B 2 113 ? 392.893 369.548 509.414 1.00 98.31  ? 113 LEU H CD1 1 
ATOM 1735 C CD2 . LEU B 2 113 ? 394.780 371.170 509.698 1.00 98.31  ? 113 LEU H CD2 1 
ATOM 1736 N N   . VAL B 2 114 ? 390.099 371.970 508.133 1.00 102.83 ? 114 VAL H N   1 
ATOM 1737 C CA  . VAL B 2 114 ? 389.238 372.836 508.927 1.00 102.83 ? 114 VAL H CA  1 
ATOM 1738 C C   . VAL B 2 114 ? 389.309 372.354 510.367 1.00 102.83 ? 114 VAL H C   1 
ATOM 1739 O O   . VAL B 2 114 ? 389.088 371.169 510.642 1.00 102.83 ? 114 VAL H O   1 
ATOM 1740 C CB  . VAL B 2 114 ? 387.795 372.837 508.401 1.00 102.83 ? 114 VAL H CB  1 
ATOM 1741 C CG1 . VAL B 2 114 ? 386.828 373.356 509.453 1.00 102.83 ? 114 VAL H CG1 1 
ATOM 1742 C CG2 . VAL B 2 114 ? 387.699 373.678 507.149 1.00 102.83 ? 114 VAL H CG2 1 
ATOM 1743 N N   . THR B 2 115 ? 389.642 373.261 511.281 1.00 109.42 ? 115 THR H N   1 
ATOM 1744 C CA  . THR B 2 115 ? 389.684 372.959 512.704 1.00 109.42 ? 115 THR H CA  1 
ATOM 1745 C C   . THR B 2 115 ? 388.758 373.899 513.454 1.00 109.42 ? 115 THR H C   1 
ATOM 1746 O O   . THR B 2 115 ? 388.544 375.040 513.036 1.00 109.42 ? 115 THR H O   1 
ATOM 1747 C CB  . THR B 2 115 ? 391.099 373.082 513.272 1.00 109.42 ? 115 THR H CB  1 
ATOM 1748 O OG1 . THR B 2 115 ? 391.755 374.206 512.675 1.00 109.42 ? 115 THR H OG1 1 
ATOM 1749 C CG2 . THR B 2 115 ? 391.900 371.820 513.006 1.00 109.42 ? 115 THR H CG2 1 
ATOM 1750 N N   . VAL B 2 116 ? 388.209 373.410 514.560 1.00 113.13 ? 116 VAL H N   1 
ATOM 1751 C CA  . VAL B 2 116 ? 387.361 374.198 515.440 1.00 113.13 ? 116 VAL H CA  1 
ATOM 1752 C C   . VAL B 2 116 ? 388.045 374.326 516.793 1.00 113.13 ? 116 VAL H C   1 
ATOM 1753 O O   . VAL B 2 116 ? 388.498 373.331 517.371 1.00 113.13 ? 116 VAL H O   1 
ATOM 1754 C CB  . VAL B 2 116 ? 385.958 373.577 515.575 1.00 113.13 ? 116 VAL H CB  1 
ATOM 1755 C CG1 . VAL B 2 116 ? 385.120 373.958 514.384 1.00 113.13 ? 116 VAL H CG1 1 
ATOM 1756 C CG2 . VAL B 2 116 ? 386.053 372.063 515.654 1.00 113.13 ? 116 VAL H CG2 1 
ATOM 1757 N N   . SER B 2 117 ? 388.135 375.555 517.289 1.00 116.14 ? 117 SER H N   1 
ATOM 1758 C CA  . SER B 2 117 ? 388.851 375.830 518.528 1.00 116.14 ? 117 SER H CA  1 
ATOM 1759 C C   . SER B 2 117 ? 388.311 377.125 519.125 1.00 116.14 ? 117 SER H C   1 
ATOM 1760 O O   . SER B 2 117 ? 387.338 377.701 518.627 1.00 116.14 ? 117 SER H O   1 
ATOM 1761 C CB  . SER B 2 117 ? 390.363 375.901 518.279 1.00 116.14 ? 117 SER H CB  1 
ATOM 1762 O OG  . SER B 2 117 ? 390.901 374.619 518.003 1.00 116.14 ? 117 SER H OG  1 
ATOM 1763 N N   . ALA B 2 118 ? 388.951 377.581 520.197 1.00 116.12 ? 118 ALA H N   1 
ATOM 1764 C CA  . ALA B 2 118 ? 388.555 378.801 520.886 1.00 116.12 ? 118 ALA H CA  1 
ATOM 1765 C C   . ALA B 2 118 ? 389.770 379.668 521.196 1.00 116.12 ? 118 ALA H C   1 
ATOM 1766 O O   . ALA B 2 118 ? 389.708 380.894 521.147 1.00 116.12 ? 118 ALA H O   1 
ATOM 1767 C CB  . ALA B 2 118 ? 387.807 378.466 522.161 1.00 116.12 ? 118 ALA H CB  1 
ATOM 1768 O OXT . ALA B 2 118 ? 390.847 379.162 521.501 1.00 116.12 ? 118 ALA H OXT 1 
ATOM 1769 N N   . SER C 3 58  ? 384.056 365.722 447.129 1.00 73.96  ? 58  SER A N   1 
ATOM 1770 C CA  . SER C 3 58  ? 383.635 366.502 448.286 1.00 73.96  ? 58  SER A CA  1 
ATOM 1771 C C   . SER C 3 58  ? 382.171 366.114 448.413 1.00 73.96  ? 58  SER A C   1 
ATOM 1772 O O   . SER C 3 58  ? 381.542 366.339 449.445 1.00 73.96  ? 58  SER A O   1 
ATOM 1773 C CB  . SER C 3 58  ? 383.773 368.001 448.009 1.00 73.96  ? 58  SER A CB  1 
ATOM 1774 O OG  . SER C 3 58  ? 382.586 368.543 447.454 1.00 73.96  ? 58  SER A OG  1 
ATOM 1775 N N   . ARG C 3 59  ? 381.636 365.531 447.344 1.00 74.31  ? 59  ARG A N   1 
ATOM 1776 C CA  . ARG C 3 59  ? 380.324 364.910 447.319 1.00 74.31  ? 59  ARG A CA  1 
ATOM 1777 C C   . ARG C 3 59  ? 380.022 363.465 447.984 1.00 74.31  ? 59  ARG A C   1 
ATOM 1778 O O   . ARG C 3 59  ? 379.053 363.152 448.681 1.00 74.31  ? 59  ARG A O   1 
ATOM 1779 C CB  . ARG C 3 59  ? 379.787 365.079 445.885 1.00 74.31  ? 59  ARG A CB  1 
ATOM 1780 C CG  . ARG C 3 59  ? 380.496 364.254 444.787 1.00 74.31  ? 59  ARG A CG  1 
ATOM 1781 C CD  . ARG C 3 59  ? 379.913 364.469 443.388 1.00 74.31  ? 59  ARG A CD  1 
ATOM 1782 N NE  . ARG C 3 59  ? 378.537 363.996 443.270 1.00 74.31  ? 59  ARG A NE  1 
ATOM 1783 C CZ  . ARG C 3 59  ? 378.199 362.737 442.997 1.00 74.31  ? 59  ARG A CZ  1 
ATOM 1784 N NH1 . ARG C 3 59  ? 379.137 361.819 442.815 1.00 74.31  ? 59  ARG A NH1 1 
ATOM 1785 N NH2 . ARG C 3 59  ? 376.923 362.396 442.910 1.00 74.31  ? 59  ARG A NH2 1 
ATOM 1786 N N   . SER C 3 60  ? 381.051 362.645 447.788 1.00 65.65  ? 60  SER A N   1 
ATOM 1787 C CA  . SER C 3 60  ? 381.188 361.373 448.475 1.00 65.65  ? 60  SER A CA  1 
ATOM 1788 C C   . SER C 3 60  ? 381.879 361.186 449.812 1.00 65.65  ? 60  SER A C   1 
ATOM 1789 O O   . SER C 3 60  ? 381.954 360.058 450.300 1.00 65.65  ? 60  SER A O   1 
ATOM 1790 C CB  . SER C 3 60  ? 381.917 360.545 447.408 1.00 65.65  ? 60  SER A CB  1 
ATOM 1791 O OG  . SER C 3 60  ? 381.640 359.162 447.542 1.00 65.65  ? 60  SER A OG  1 
ATOM 1792 N N   . GLU C 3 61  ? 382.389 362.256 450.408 1.00 60.31  ? 61  GLU A N   1 
ATOM 1793 C CA  . GLU C 3 61  ? 383.033 362.168 451.707 1.00 60.31  ? 61  GLU A CA  1 
ATOM 1794 C C   . GLU C 3 61  ? 382.033 361.923 452.825 1.00 60.31  ? 61  GLU A C   1 
ATOM 1795 O O   . GLU C 3 61  ? 382.392 361.337 453.850 1.00 60.31  ? 61  GLU A O   1 
ATOM 1796 C CB  . GLU C 3 61  ? 383.829 363.453 451.961 1.00 60.31  ? 61  GLU A CB  1 
ATOM 1797 C CG  . GLU C 3 61  ? 384.692 363.468 453.211 1.00 60.31  ? 61  GLU A CG  1 
ATOM 1798 C CD  . GLU C 3 61  ? 386.066 362.879 452.985 1.00 60.31  ? 61  GLU A CD  1 
ATOM 1799 O OE1 . GLU C 3 61  ? 386.731 363.290 452.013 1.00 60.31  ? 61  GLU A OE1 1 
ATOM 1800 O OE2 . GLU C 3 61  ? 386.481 362.008 453.779 1.00 60.31  ? 61  GLU A OE2 1 
ATOM 1801 N N   . SER C 3 62  ? 380.778 362.306 452.629 1.00 55.55  ? 62  SER A N   1 
ATOM 1802 C CA  . SER C 3 62  ? 379.752 362.189 453.650 1.00 55.55  ? 62  SER A CA  1 
ATOM 1803 C C   . SER C 3 62  ? 378.875 360.963 453.475 1.00 55.55  ? 62  SER A C   1 
ATOM 1804 O O   . SER C 3 62  ? 377.799 360.905 454.072 1.00 55.55  ? 62  SER A O   1 
ATOM 1805 C CB  . SER C 3 62  ? 378.880 363.437 453.660 1.00 55.55  ? 62  SER A CB  1 
ATOM 1806 O OG  . SER C 3 62  ? 377.990 363.411 452.566 1.00 55.55  ? 62  SER A OG  1 
ATOM 1807 N N   . SER C 3 63  ? 379.299 359.984 452.682 1.00 52.88  ? 63  SER A N   1 
ATOM 1808 C CA  . SER C 3 63  ? 378.522 358.766 452.543 1.00 52.88  ? 63  SER A CA  1 
ATOM 1809 C C   . SER C 3 63  ? 378.694 357.892 453.780 1.00 52.88  ? 63  SER A C   1 
ATOM 1810 O O   . SER C 3 63  ? 379.459 358.205 454.687 1.00 52.88  ? 63  SER A O   1 
ATOM 1811 C CB  . SER C 3 63  ? 378.935 358.010 451.290 1.00 52.88  ? 63  SER A CB  1 
ATOM 1812 O OG  . SER C 3 63  ? 380.147 357.320 451.503 1.00 52.88  ? 63  SER A OG  1 
ATOM 1813 N N   . ILE C 3 64  ? 377.961 356.779 453.817 1.00 51.01  ? 64  ILE A N   1 
ATOM 1814 C CA  . ILE C 3 64  ? 377.996 355.925 455.000 1.00 51.01  ? 64  ILE A CA  1 
ATOM 1815 C C   . ILE C 3 64  ? 379.295 355.136 455.066 1.00 51.01  ? 64  ILE A C   1 
ATOM 1816 O O   . ILE C 3 64  ? 379.930 355.061 456.126 1.00 51.01  ? 64  ILE A O   1 
ATOM 1817 C CB  . ILE C 3 64  ? 376.763 355.005 455.020 1.00 51.01  ? 64  ILE A CB  1 
ATOM 1818 C CG1 . ILE C 3 64  ? 375.510 355.819 455.326 1.00 51.01  ? 64  ILE A CG1 1 
ATOM 1819 C CG2 . ILE C 3 64  ? 376.910 353.901 456.045 1.00 51.01  ? 64  ILE A CG2 1 
ATOM 1820 C CD1 . ILE C 3 64  ? 375.474 356.370 456.726 1.00 51.01  ? 64  ILE A CD1 1 
ATOM 1821 N N   . GLU C 3 65  ? 379.730 354.569 453.941 1.00 52.63  ? 65  GLU A N   1 
ATOM 1822 C CA  . GLU C 3 65  ? 380.966 353.796 453.916 1.00 52.63  ? 65  GLU A CA  1 
ATOM 1823 C C   . GLU C 3 65  ? 382.186 354.680 454.145 1.00 52.63  ? 65  GLU A C   1 
ATOM 1824 O O   . GLU C 3 65  ? 383.180 354.233 454.718 1.00 52.63  ? 65  GLU A O   1 
ATOM 1825 C CB  . GLU C 3 65  ? 381.079 353.053 452.588 1.00 52.63  ? 65  GLU A CB  1 
ATOM 1826 C CG  . GLU C 3 65  ? 382.188 352.028 452.524 1.00 52.63  ? 65  GLU A CG  1 
ATOM 1827 C CD  . GLU C 3 65  ? 381.819 350.724 453.192 1.00 52.63  ? 65  GLU A CD  1 
ATOM 1828 O OE1 . GLU C 3 65  ? 380.613 350.420 453.258 1.00 52.63  ? 65  GLU A OE1 1 
ATOM 1829 O OE2 . GLU C 3 65  ? 382.735 350.000 453.640 1.00 52.63  ? 65  GLU A OE2 1 
ATOM 1830 N N   . ASN C 3 66  ? 382.126 355.943 453.743 1.00 53.56  ? 66  ASN A N   1 
ATOM 1831 C CA  . ASN C 3 66  ? 383.227 356.852 454.032 1.00 53.56  ? 66  ASN A CA  1 
ATOM 1832 C C   . ASN C 3 66  ? 383.180 357.401 455.447 1.00 53.56  ? 66  ASN A C   1 
ATOM 1833 O O   . ASN C 3 66  ? 384.110 358.098 455.856 1.00 53.56  ? 66  ASN A O   1 
ATOM 1834 C CB  . ASN C 3 66  ? 383.233 358.012 453.042 1.00 53.56  ? 66  ASN A CB  1 
ATOM 1835 C CG  . ASN C 3 66  ? 383.680 357.597 451.669 1.00 53.56  ? 66  ASN A CG  1 
ATOM 1836 O OD1 . ASN C 3 66  ? 384.819 357.830 451.282 1.00 53.56  ? 66  ASN A OD1 1 
ATOM 1837 N ND2 . ASN C 3 66  ? 382.785 356.979 450.920 1.00 53.56  ? 66  ASN A ND2 1 
ATOM 1838 N N   . PHE C 3 67  ? 382.128 357.109 456.198 1.00 50.58  ? 67  PHE A N   1 
ATOM 1839 C CA  . PHE C 3 67  ? 381.959 357.597 457.556 1.00 50.58  ? 67  PHE A CA  1 
ATOM 1840 C C   . PHE C 3 67  ? 382.341 356.562 458.599 1.00 50.58  ? 67  PHE A C   1 
ATOM 1841 O O   . PHE C 3 67  ? 382.963 356.902 459.607 1.00 50.58  ? 67  PHE A O   1 
ATOM 1842 C CB  . PHE C 3 67  ? 380.503 358.015 457.766 1.00 50.58  ? 67  PHE A CB  1 
ATOM 1843 C CG  . PHE C 3 67  ? 380.250 358.750 459.038 1.00 50.58  ? 67  PHE A CG  1 
ATOM 1844 C CD1 . PHE C 3 67  ? 380.625 360.068 459.173 1.00 50.58  ? 67  PHE A CD1 1 
ATOM 1845 C CD2 . PHE C 3 67  ? 379.607 358.130 460.088 1.00 50.58  ? 67  PHE A CD2 1 
ATOM 1846 C CE1 . PHE C 3 67  ? 380.382 360.749 460.340 1.00 50.58  ? 67  PHE A CE1 1 
ATOM 1847 C CE2 . PHE C 3 67  ? 379.362 358.805 461.256 1.00 50.58  ? 67  PHE A CE2 1 
ATOM 1848 C CZ  . PHE C 3 67  ? 379.749 360.113 461.382 1.00 50.58  ? 67  PHE A CZ  1 
ATOM 1849 N N   . LEU C 3 68  ? 381.998 355.299 458.364 1.00 49.40  ? 68  LEU A N   1 
ATOM 1850 C CA  . LEU C 3 68  ? 382.111 354.262 459.375 1.00 49.40  ? 68  LEU A CA  1 
ATOM 1851 C C   . LEU C 3 68  ? 383.222 353.262 459.111 1.00 49.40  ? 68  LEU A C   1 
ATOM 1852 O O   . LEU C 3 68  ? 383.724 352.656 460.060 1.00 49.40  ? 68  LEU A O   1 
ATOM 1853 C CB  . LEU C 3 68  ? 380.785 353.517 459.497 1.00 49.40  ? 68  LEU A CB  1 
ATOM 1854 C CG  . LEU C 3 68  ? 379.743 354.275 460.310 1.00 49.40  ? 68  LEU A CG  1 
ATOM 1855 C CD1 . LEU C 3 68  ? 378.411 353.572 460.276 1.00 49.40  ? 68  LEU A CD1 1 
ATOM 1856 C CD2 . LEU C 3 68  ? 380.234 354.403 461.726 1.00 49.40  ? 68  LEU A CD2 1 
ATOM 1857 N N   . CYS C 3 69  ? 383.636 353.068 457.860 1.00 49.12  ? 69  CYS A N   1 
ATOM 1858 C CA  . CYS C 3 69  ? 384.695 352.109 457.539 1.00 49.12  ? 69  CYS A CA  1 
ATOM 1859 C C   . CYS C 3 69  ? 386.046 352.745 457.851 1.00 49.12  ? 69  CYS A C   1 
ATOM 1860 O O   . CYS C 3 69  ? 386.820 353.113 456.968 1.00 49.12  ? 69  CYS A O   1 
ATOM 1861 C CB  . CYS C 3 69  ? 384.593 351.674 456.084 1.00 49.12  ? 69  CYS A CB  1 
ATOM 1862 S SG  . CYS C 3 69  ? 385.727 350.398 455.516 1.00 49.12  ? 69  CYS A SG  1 
ATOM 1863 N N   . ARG C 3 70  ? 386.325 352.883 459.144 1.00 48.67  ? 70  ARG A N   1 
ATOM 1864 C CA  . ARG C 3 70  ? 387.604 353.339 459.663 1.00 48.67  ? 70  ARG A CA  1 
ATOM 1865 C C   . ARG C 3 70  ? 388.051 352.352 460.727 1.00 48.67  ? 70  ARG A C   1 
ATOM 1866 O O   . ARG C 3 70  ? 387.229 351.748 461.416 1.00 48.67  ? 70  ARG A O   1 
ATOM 1867 C CB  . ARG C 3 70  ? 387.510 354.745 460.266 1.00 48.67  ? 70  ARG A CB  1 
ATOM 1868 C CG  . ARG C 3 70  ? 386.937 355.810 459.363 1.00 48.67  ? 70  ARG A CG  1 
ATOM 1869 C CD  . ARG C 3 70  ? 387.833 356.064 458.190 1.00 48.67  ? 70  ARG A CD  1 
ATOM 1870 N NE  . ARG C 3 70  ? 387.266 357.053 457.287 1.00 48.67  ? 70  ARG A NE  1 
ATOM 1871 C CZ  . ARG C 3 70  ? 387.551 358.344 457.337 1.00 48.67  ? 70  ARG A CZ  1 
ATOM 1872 N NH1 . ARG C 3 70  ? 388.400 358.792 458.244 1.00 48.67  ? 70  ARG A NH1 1 
ATOM 1873 N NH2 . ARG C 3 70  ? 386.994 359.183 456.479 1.00 48.67  ? 70  ARG A NH2 1 
ATOM 1874 N N   . SER C 3 71  ? 389.357 352.187 460.881 1.00 45.37  ? 71  SER A N   1 
ATOM 1875 C CA  . SER C 3 71  ? 389.888 351.279 461.881 1.00 45.37  ? 71  SER A CA  1 
ATOM 1876 C C   . SER C 3 71  ? 390.043 352.006 463.204 1.00 45.37  ? 71  SER A C   1 
ATOM 1877 O O   . SER C 3 71  ? 390.330 353.203 463.239 1.00 45.37  ? 71  SER A O   1 
ATOM 1878 C CB  . SER C 3 71  ? 391.229 350.702 461.456 1.00 45.37  ? 71  SER A CB  1 
ATOM 1879 O OG  . SER C 3 71  ? 391.940 350.260 462.592 1.00 45.37  ? 71  SER A OG  1 
ATOM 1880 N N   . ALA C 3 72  ? 389.849 351.274 464.297 1.00 44.31  ? 72  ALA A N   1 
ATOM 1881 C CA  . ALA C 3 72  ? 389.848 351.876 465.619 1.00 44.31  ? 72  ALA A CA  1 
ATOM 1882 C C   . ALA C 3 72  ? 390.255 350.844 466.653 1.00 44.31  ? 72  ALA A C   1 
ATOM 1883 O O   . ALA C 3 72  ? 389.761 349.717 466.635 1.00 44.31  ? 72  ALA A O   1 
ATOM 1884 C CB  . ALA C 3 72  ? 388.470 352.441 465.959 1.00 44.31  ? 72  ALA A CB  1 
ATOM 1885 N N   . CYS C 3 73  ? 391.156 351.232 467.550 1.00 44.83  ? 73  CYS A N   1 
ATOM 1886 C CA  . CYS C 3 73  ? 391.585 350.360 468.638 1.00 44.83  ? 73  CYS A CA  1 
ATOM 1887 C C   . CYS C 3 73  ? 390.468 350.298 469.666 1.00 44.83  ? 73  CYS A C   1 
ATOM 1888 O O   . CYS C 3 73  ? 389.990 351.333 470.133 1.00 44.83  ? 73  CYS A O   1 
ATOM 1889 C CB  . CYS C 3 73  ? 392.878 350.873 469.264 1.00 44.83  ? 73  CYS A CB  1 
ATOM 1890 S SG  . CYS C 3 73  ? 393.413 350.001 470.750 1.00 44.83  ? 73  CYS A SG  1 
ATOM 1891 N N   . VAL C 3 74  ? 390.045 349.089 470.019 1.00 43.94  ? 74  VAL A N   1 
ATOM 1892 C CA  . VAL C 3 74  ? 388.900 348.910 470.901 1.00 43.94  ? 74  VAL A CA  1 
ATOM 1893 C C   . VAL C 3 74  ? 389.239 348.186 472.189 1.00 43.94  ? 74  VAL A C   1 
ATOM 1894 O O   . VAL C 3 74  ? 388.450 348.263 473.143 1.00 43.94  ? 74  VAL A O   1 
ATOM 1895 C CB  . VAL C 3 74  ? 387.750 348.183 470.181 1.00 43.94  ? 74  VAL A CB  1 
ATOM 1896 C CG1 . VAL C 3 74  ? 387.075 349.118 469.214 1.00 43.94  ? 74  VAL A CG1 1 
ATOM 1897 C CG2 . VAL C 3 74  ? 388.288 346.992 469.455 1.00 43.94  ? 74  VAL A CG2 1 
ATOM 1898 N N   . TYR C 3 75  ? 390.370 347.494 472.264 1.00 48.65  ? 75  TYR A N   1 
ATOM 1899 C CA  . TYR C 3 75  ? 390.714 346.770 473.476 1.00 48.65  ? 75  TYR A CA  1 
ATOM 1900 C C   . TYR C 3 75  ? 392.223 346.657 473.584 1.00 48.65  ? 75  TYR A C   1 
ATOM 1901 O O   . TYR C 3 75  ? 392.938 346.705 472.585 1.00 48.65  ? 75  TYR A O   1 
ATOM 1902 C CB  . TYR C 3 75  ? 390.071 345.387 473.497 1.00 48.65  ? 75  TYR A CB  1 
ATOM 1903 C CG  . TYR C 3 75  ? 390.117 344.721 474.843 1.00 48.65  ? 75  TYR A CG  1 
ATOM 1904 C CD1 . TYR C 3 75  ? 389.431 345.250 475.925 1.00 48.65  ? 75  TYR A CD1 1 
ATOM 1905 C CD2 . TYR C 3 75  ? 390.856 343.568 475.036 1.00 48.65  ? 75  TYR A CD2 1 
ATOM 1906 C CE1 . TYR C 3 75  ? 389.476 344.642 477.155 1.00 48.65  ? 75  TYR A CE1 1 
ATOM 1907 C CE2 . TYR C 3 75  ? 390.902 342.955 476.258 1.00 48.65  ? 75  TYR A CE2 1 
ATOM 1908 C CZ  . TYR C 3 75  ? 390.216 343.496 477.311 1.00 48.65  ? 75  TYR A CZ  1 
ATOM 1909 O OH  . TYR C 3 75  ? 390.270 342.876 478.530 1.00 48.65  ? 75  TYR A OH  1 
ATOM 1910 N N   . TYR C 3 76  ? 392.700 346.501 474.815 1.00 53.80  ? 76  TYR A N   1 
ATOM 1911 C CA  . TYR C 3 76  ? 394.132 346.479 475.092 1.00 53.80  ? 76  TYR A CA  1 
ATOM 1912 C C   . TYR C 3 76  ? 394.342 345.750 476.405 1.00 53.80  ? 76  TYR A C   1 
ATOM 1913 O O   . TYR C 3 76  ? 393.891 346.229 477.448 1.00 53.80  ? 76  TYR A O   1 
ATOM 1914 C CB  . TYR C 3 76  ? 394.669 347.903 475.160 1.00 53.80  ? 76  TYR A CB  1 
ATOM 1915 C CG  . TYR C 3 76  ? 395.954 348.078 475.926 1.00 53.80  ? 76  TYR A CG  1 
ATOM 1916 C CD1 . TYR C 3 76  ? 397.166 347.697 475.373 1.00 53.80  ? 76  TYR A CD1 1 
ATOM 1917 C CD2 . TYR C 3 76  ? 395.959 348.656 477.191 1.00 53.80  ? 76  TYR A CD2 1 
ATOM 1918 C CE1 . TYR C 3 76  ? 398.345 347.866 476.063 1.00 53.80  ? 76  TYR A CE1 1 
ATOM 1919 C CE2 . TYR C 3 76  ? 397.132 348.822 477.891 1.00 53.80  ? 76  TYR A CE2 1 
ATOM 1920 C CZ  . TYR C 3 76  ? 398.326 348.423 477.319 1.00 53.80  ? 76  TYR A CZ  1 
ATOM 1921 O OH  . TYR C 3 76  ? 399.509 348.586 478.000 1.00 53.80  ? 76  TYR A OH  1 
ATOM 1922 N N   . ALA C 3 77  ? 395.005 344.597 476.363 1.00 49.68  ? 77  ALA A N   1 
ATOM 1923 C CA  . ALA C 3 77  ? 395.229 343.810 477.566 1.00 49.68  ? 77  ALA A CA  1 
ATOM 1924 C C   . ALA C 3 77  ? 396.558 343.088 477.472 1.00 49.68  ? 77  ALA A C   1 
ATOM 1925 O O   . ALA C 3 77  ? 397.089 342.863 476.386 1.00 49.68  ? 77  ALA A O   1 
ATOM 1926 C CB  . ALA C 3 77  ? 394.120 342.790 477.797 1.00 49.68  ? 77  ALA A CB  1 
ATOM 1927 N N   . THR C 3 78  ? 397.091 342.726 478.634 1.00 48.65  ? 78  THR A N   1 
ATOM 1928 C CA  . THR C 3 78  ? 398.352 342.012 478.736 1.00 48.65  ? 78  THR A CA  1 
ATOM 1929 C C   . THR C 3 78  ? 398.125 340.660 479.393 1.00 48.65  ? 78  THR A C   1 
ATOM 1930 O O   . THR C 3 78  ? 397.118 340.448 480.070 1.00 48.65  ? 78  THR A O   1 
ATOM 1931 C CB  . THR C 3 78  ? 399.391 342.788 479.553 1.00 48.65  ? 78  THR A CB  1 
ATOM 1932 O OG1 . THR C 3 78  ? 399.143 342.593 480.949 1.00 48.65  ? 78  THR A OG1 1 
ATOM 1933 C CG2 . THR C 3 78  ? 399.338 344.270 479.244 1.00 48.65  ? 78  THR A CG2 1 
ATOM 1934 N N   . TYR C 3 79  ? 399.084 339.755 479.205 1.00 47.50  ? 79  TYR A N   1 
ATOM 1935 C CA  . TYR C 3 79  ? 399.015 338.427 479.794 1.00 47.50  ? 79  TYR A CA  1 
ATOM 1936 C C   . TYR C 3 79  ? 400.381 337.776 479.916 1.00 47.50  ? 79  TYR A C   1 
ATOM 1937 O O   . TYR C 3 79  ? 401.177 337.823 478.982 1.00 47.50  ? 79  TYR A O   1 
ATOM 1938 C CB  . TYR C 3 79  ? 398.047 337.515 479.030 1.00 47.50  ? 79  TYR A CB  1 
ATOM 1939 C CG  . TYR C 3 79  ? 398.322 337.331 477.555 1.00 47.50  ? 79  TYR A CG  1 
ATOM 1940 C CD1 . TYR C 3 79  ? 397.865 338.247 476.623 1.00 47.50  ? 79  TYR A CD1 1 
ATOM 1941 C CD2 . TYR C 3 79  ? 398.998 336.217 477.093 1.00 47.50  ? 79  TYR A CD2 1 
ATOM 1942 C CE1 . TYR C 3 79  ? 398.100 338.073 475.283 1.00 47.50  ? 79  TYR A CE1 1 
ATOM 1943 C CE2 . TYR C 3 79  ? 399.232 336.037 475.756 1.00 47.50  ? 79  TYR A CE2 1 
ATOM 1944 C CZ  . TYR C 3 79  ? 398.783 336.968 474.857 1.00 47.50  ? 79  TYR A CZ  1 
ATOM 1945 O OH  . TYR C 3 79  ? 399.014 336.795 473.517 1.00 47.50  ? 79  TYR A OH  1 
ATOM 1946 N N   . THR C 3 80  ? 400.644 337.173 481.066 1.00 54.30  ? 80  THR A N   1 
ATOM 1947 C CA  . THR C 3 80  ? 401.857 336.398 481.294 1.00 54.30  ? 80  THR A CA  1 
ATOM 1948 C C   . THR C 3 80  ? 401.661 334.902 481.134 1.00 54.30  ? 80  THR A C   1 
ATOM 1949 O O   . THR C 3 80  ? 400.534 334.407 481.161 1.00 54.30  ? 80  THR A O   1 
ATOM 1950 C CB  . THR C 3 80  ? 402.378 336.705 482.698 1.00 54.30  ? 80  THR A CB  1 
ATOM 1951 O OG1 . THR C 3 80  ? 402.639 338.106 482.818 1.00 54.30  ? 80  THR A OG1 1 
ATOM 1952 C CG2 . THR C 3 80  ? 403.627 335.928 482.988 1.00 54.30  ? 80  THR A CG2 1 
ATOM 1953 N N   . ASN C 3 81  ? 402.758 334.169 480.961 1.00 58.28  ? 81  ASN A N   1 
ATOM 1954 C CA  . ASN C 3 81  ? 402.680 332.792 480.489 1.00 58.28  ? 81  ASN A CA  1 
ATOM 1955 C C   . ASN C 3 81  ? 402.626 331.837 481.676 1.00 58.28  ? 81  ASN A C   1 
ATOM 1956 O O   . ASN C 3 81  ? 401.823 330.900 481.673 1.00 58.28  ? 81  ASN A O   1 
ATOM 1957 C CB  . ASN C 3 81  ? 403.822 332.377 479.559 1.00 58.28  ? 81  ASN A CB  1 
ATOM 1958 C CG  . ASN C 3 81  ? 405.176 332.793 480.073 1.00 58.28  ? 81  ASN A CG  1 
ATOM 1959 O OD1 . ASN C 3 81  ? 405.317 333.223 481.212 1.00 58.28  ? 81  ASN A OD1 1 
ATOM 1960 N ND2 . ASN C 3 81  ? 406.186 332.673 479.226 1.00 58.28  ? 81  ASN A ND2 1 
ATOM 1961 N N   . ASN C 3 82  ? 403.459 332.039 482.690 1.00 63.49  ? 82  ASN A N   1 
ATOM 1962 C CA  . ASN C 3 82  ? 403.621 331.067 483.760 1.00 63.49  ? 82  ASN A CA  1 
ATOM 1963 C C   . ASN C 3 82  ? 402.712 331.321 484.951 1.00 63.49  ? 82  ASN A C   1 
ATOM 1964 O O   . ASN C 3 82  ? 402.752 330.554 485.916 1.00 63.49  ? 82  ASN A O   1 
ATOM 1965 C CB  . ASN C 3 82  ? 405.072 331.050 484.231 1.00 63.49  ? 82  ASN A CB  1 
ATOM 1966 C CG  . ASN C 3 82  ? 405.585 332.428 484.567 1.00 63.49  ? 82  ASN A CG  1 
ATOM 1967 O OD1 . ASN C 3 82  ? 405.321 332.959 485.643 1.00 63.49  ? 82  ASN A OD1 1 
ATOM 1968 N ND2 . ASN C 3 82  ? 406.324 333.018 483.642 1.00 63.49  ? 82  ASN A ND2 1 
ATOM 1969 N N   . SER C 3 83  ? 401.895 332.367 484.911 1.00 65.99  ? 83  SER A N   1 
ATOM 1970 C CA  . SER C 3 83  ? 401.206 332.826 486.109 1.00 65.99  ? 83  SER A CA  1 
ATOM 1971 C C   . SER C 3 83  ? 400.028 331.954 486.514 1.00 65.99  ? 83  SER A C   1 
ATOM 1972 O O   . SER C 3 83  ? 399.628 332.007 487.684 1.00 65.99  ? 83  SER A O   1 
ATOM 1973 C CB  . SER C 3 83  ? 400.701 334.248 485.901 1.00 65.99  ? 83  SER A CB  1 
ATOM 1974 O OG  . SER C 3 83  ? 399.974 334.335 484.688 1.00 65.99  ? 83  SER A OG  1 
ATOM 1975 N N   . LYS C 3 84  ? 399.454 331.195 485.571 1.00 67.07  ? 84  LYS A N   1 
ATOM 1976 C CA  . LYS C 3 84  ? 398.182 330.475 485.687 1.00 67.07  ? 84  LYS A CA  1 
ATOM 1977 C C   . LYS C 3 84  ? 397.043 331.416 486.066 1.00 67.07  ? 84  LYS A C   1 
ATOM 1978 O O   . LYS C 3 84  ? 396.085 331.019 486.733 1.00 67.07  ? 84  LYS A O   1 
ATOM 1979 C CB  . LYS C 3 84  ? 398.290 329.304 486.672 1.00 67.07  ? 84  LYS A CB  1 
ATOM 1980 C CG  . LYS C 3 84  ? 399.257 328.207 486.236 1.00 67.07  ? 84  LYS A CG  1 
ATOM 1981 C CD  . LYS C 3 84  ? 399.176 327.921 484.737 1.00 67.07  ? 84  LYS A CD  1 
ATOM 1982 C CE  . LYS C 3 84  ? 400.378 327.124 484.242 1.00 67.07  ? 84  LYS A CE  1 
ATOM 1983 N NZ  . LYS C 3 84  ? 400.063 326.305 483.037 1.00 67.07  ? 84  LYS A NZ  1 
ATOM 1984 N N   . LYS C 3 85  ? 397.165 332.674 485.653 1.00 65.07  ? 85  LYS A N   1 
ATOM 1985 C CA  . LYS C 3 85  ? 396.101 333.661 485.667 1.00 65.07  ? 85  LYS A CA  1 
ATOM 1986 C C   . LYS C 3 85  ? 396.149 334.544 484.427 1.00 65.07  ? 85  LYS A C   1 
ATOM 1987 O O   . LYS C 3 85  ? 395.172 335.239 484.133 1.00 65.07  ? 85  LYS A O   1 
ATOM 1988 C CB  . LYS C 3 85  ? 396.196 334.510 486.949 1.00 65.07  ? 85  LYS A CB  1 
ATOM 1989 C CG  . LYS C 3 85  ? 394.941 335.286 487.331 1.00 65.07  ? 85  LYS A CG  1 
ATOM 1990 C CD  . LYS C 3 85  ? 393.701 334.400 487.378 1.00 65.07  ? 85  LYS A CD  1 
ATOM 1991 C CE  . LYS C 3 85  ? 393.751 333.388 488.510 1.00 65.07  ? 85  LYS A CE  1 
ATOM 1992 N NZ  . LYS C 3 85  ? 392.556 332.503 488.487 1.00 65.07  ? 85  LYS A NZ  1 
ATOM 1993 N N   . GLY C 3 86  ? 397.247 334.498 483.674 1.00 56.09  ? 86  GLY A N   1 
ATOM 1994 C CA  . GLY C 3 86  ? 397.414 335.301 482.484 1.00 56.09  ? 86  GLY A CA  1 
ATOM 1995 C C   . GLY C 3 86  ? 396.929 334.660 481.200 1.00 56.09  ? 86  GLY A C   1 
ATOM 1996 O O   . GLY C 3 86  ? 397.571 333.755 480.662 1.00 56.09  ? 86  GLY A O   1 
ATOM 1997 N N   . PHE C 3 87  ? 395.779 335.137 480.726 1.00 50.56  ? 87  PHE A N   1 
ATOM 1998 C CA  . PHE C 3 87  ? 395.236 334.893 479.396 1.00 50.56  ? 87  PHE A CA  1 
ATOM 1999 C C   . PHE C 3 87  ? 394.121 335.905 479.188 1.00 50.56  ? 87  PHE A C   1 
ATOM 2000 O O   . PHE C 3 87  ? 393.399 336.252 480.122 1.00 50.56  ? 87  PHE A O   1 
ATOM 2001 C CB  . PHE C 3 87  ? 394.737 333.452 479.211 1.00 50.56  ? 87  PHE A CB  1 
ATOM 2002 C CG  . PHE C 3 87  ? 393.421 333.158 479.864 1.00 50.56  ? 87  PHE A CG  1 
ATOM 2003 C CD1 . PHE C 3 87  ? 393.301 333.127 481.241 1.00 50.56  ? 87  PHE A CD1 1 
ATOM 2004 C CD2 . PHE C 3 87  ? 392.311 332.875 479.098 1.00 50.56  ? 87  PHE A CD2 1 
ATOM 2005 C CE1 . PHE C 3 87  ? 392.092 332.848 481.836 1.00 50.56  ? 87  PHE A CE1 1 
ATOM 2006 C CE2 . PHE C 3 87  ? 391.104 332.593 479.688 1.00 50.56  ? 87  PHE A CE2 1 
ATOM 2007 C CZ  . PHE C 3 87  ? 390.996 332.579 481.058 1.00 50.56  ? 87  PHE A CZ  1 
ATOM 2008 N N   . ALA C 3 88  ? 394.001 336.398 477.964 1.00 47.84  ? 88  ALA A N   1 
ATOM 2009 C CA  . ALA C 3 88  ? 393.146 337.542 477.692 1.00 47.84  ? 88  ALA A CA  1 
ATOM 2010 C C   . ALA C 3 88  ? 391.734 337.100 477.329 1.00 47.84  ? 88  ALA A C   1 
ATOM 2011 O O   . ALA C 3 88  ? 391.475 335.936 477.030 1.00 47.84  ? 88  ALA A O   1 
ATOM 2012 C CB  . ALA C 3 88  ? 393.741 338.398 476.575 1.00 47.84  ? 88  ALA A CB  1 
ATOM 2013 N N   . GLU C 3 89  ? 390.817 338.066 477.345 1.00 50.84  ? 89  GLU A N   1 
ATOM 2014 C CA  . GLU C 3 89  ? 389.401 337.804 477.125 1.00 50.84  ? 89  GLU A CA  1 
ATOM 2015 C C   . GLU C 3 89  ? 388.718 339.117 476.785 1.00 50.84  ? 89  GLU A C   1 
ATOM 2016 O O   . GLU C 3 89  ? 388.903 340.105 477.498 1.00 50.84  ? 89  GLU A O   1 
ATOM 2017 C CB  . GLU C 3 89  ? 388.765 337.180 478.370 1.00 50.84  ? 89  GLU A CB  1 
ATOM 2018 C CG  . GLU C 3 89  ? 387.274 337.407 478.502 1.00 50.84  ? 89  GLU A CG  1 
ATOM 2019 C CD  . GLU C 3 89  ? 386.772 337.163 479.907 1.00 50.84  ? 89  GLU A CD  1 
ATOM 2020 O OE1 . GLU C 3 89  ? 387.554 336.651 480.736 1.00 50.84  ? 89  GLU A OE1 1 
ATOM 2021 O OE2 . GLU C 3 89  ? 385.597 337.485 480.184 1.00 50.84  ? 89  GLU A OE2 1 
ATOM 2022 N N   . TRP C 3 90  ? 387.935 339.132 475.710 1.00 45.28  ? 90  TRP A N   1 
ATOM 2023 C CA  . TRP C 3 90  ? 387.210 340.333 475.314 1.00 45.28  ? 90  TRP A CA  1 
ATOM 2024 C C   . TRP C 3 90  ? 385.967 339.935 474.540 1.00 45.28  ? 90  TRP A C   1 
ATOM 2025 O O   . TRP C 3 90  ? 386.065 339.228 473.536 1.00 45.28  ? 90  TRP A O   1 
ATOM 2026 C CB  . TRP C 3 90  ? 388.081 341.254 474.465 1.00 45.28  ? 90  TRP A CB  1 
ATOM 2027 C CG  . TRP C 3 90  ? 387.344 342.437 473.972 1.00 45.28  ? 90  TRP A CG  1 
ATOM 2028 C CD1 . TRP C 3 90  ? 386.740 343.388 474.726 1.00 45.28  ? 90  TRP A CD1 1 
ATOM 2029 C CD2 . TRP C 3 90  ? 387.115 342.799 472.612 1.00 45.28  ? 90  TRP A CD2 1 
ATOM 2030 N NE1 . TRP C 3 90  ? 386.150 344.325 473.924 1.00 45.28  ? 90  TRP A NE1 1 
ATOM 2031 C CE2 . TRP C 3 90  ? 386.368 343.984 472.618 1.00 45.28  ? 90  TRP A CE2 1 
ATOM 2032 C CE3 . TRP C 3 90  ? 387.470 342.236 471.390 1.00 45.28  ? 90  TRP A CE3 1 
ATOM 2033 C CZ2 . TRP C 3 90  ? 385.968 344.615 471.453 1.00 45.28  ? 90  TRP A CZ2 1 
ATOM 2034 C CZ3 . TRP C 3 90  ? 387.073 342.865 470.235 1.00 45.28  ? 90  TRP A CZ3 1 
ATOM 2035 C CH2 . TRP C 3 90  ? 386.330 344.040 470.274 1.00 45.28  ? 90  TRP A CH2 1 
ATOM 2036 N N   . VAL C 3 91  ? 384.806 340.383 475.003 1.00 44.62  ? 91  VAL A N   1 
ATOM 2037 C CA  . VAL C 3 91  ? 383.559 340.162 474.283 1.00 44.62  ? 91  VAL A CA  1 
ATOM 2038 C C   . VAL C 3 91  ? 383.404 341.241 473.223 1.00 44.62  ? 91  VAL A C   1 
ATOM 2039 O O   . VAL C 3 91  ? 383.672 342.420 473.471 1.00 44.62  ? 91  VAL A O   1 
ATOM 2040 C CB  . VAL C 3 91  ? 382.372 340.130 475.255 1.00 44.62  ? 91  VAL A CB  1 
ATOM 2041 C CG1 . VAL C 3 91  ? 382.435 338.884 476.085 1.00 44.62  ? 91  VAL A CG1 1 
ATOM 2042 C CG2 . VAL C 3 91  ? 382.410 341.314 476.195 1.00 44.62  ? 91  VAL A CG2 1 
ATOM 2043 N N   . ILE C 3 92  ? 383.010 340.837 472.020 1.00 45.02  ? 92  ILE A N   1 
ATOM 2044 C CA  . ILE C 3 92  ? 383.017 341.757 470.888 1.00 45.02  ? 92  ILE A CA  1 
ATOM 2045 C C   . ILE C 3 92  ? 381.806 342.673 470.991 1.00 45.02  ? 92  ILE A C   1 
ATOM 2046 O O   . ILE C 3 92  ? 380.684 342.258 470.698 1.00 45.02  ? 92  ILE A O   1 
ATOM 2047 C CB  . ILE C 3 92  ? 383.016 341.008 469.555 1.00 45.02  ? 92  ILE A CB  1 
ATOM 2048 C CG1 . ILE C 3 92  ? 384.117 339.961 469.525 1.00 45.02  ? 92  ILE A CG1 1 
ATOM 2049 C CG2 . ILE C 3 92  ? 383.186 341.980 468.414 1.00 45.02  ? 92  ILE A CG2 1 
ATOM 2050 C CD1 . ILE C 3 92  ? 384.188 339.221 468.223 1.00 45.02  ? 92  ILE A CD1 1 
ATOM 2051 N N   . ASN C 3 93  ? 382.026 343.921 471.395 1.00 49.14  ? 93  ASN A N   1 
ATOM 2052 C CA  . ASN C 3 93  ? 380.996 344.945 471.324 1.00 49.14  ? 93  ASN A CA  1 
ATOM 2053 C C   . ASN C 3 93  ? 381.644 346.308 471.165 1.00 49.14  ? 93  ASN A C   1 
ATOM 2054 O O   . ASN C 3 93  ? 382.803 346.518 471.526 1.00 49.14  ? 93  ASN A O   1 
ATOM 2055 C CB  . ASN C 3 93  ? 380.060 344.896 472.535 1.00 49.14  ? 93  ASN A CB  1 
ATOM 2056 C CG  . ASN C 3 93  ? 380.783 344.952 473.865 1.00 49.14  ? 93  ASN A CG  1 
ATOM 2057 O OD1 . ASN C 3 93  ? 381.983 345.190 473.957 1.00 49.14  ? 93  ASN A OD1 1 
ATOM 2058 N ND2 . ASN C 3 93  ? 380.035 344.682 474.917 1.00 49.14  ? 93  ASN A ND2 1 
ATOM 2059 N N   . THR C 3 94  ? 380.879 347.247 470.626 1.00 50.31  ? 94  THR A N   1 
ATOM 2060 C CA  . THR C 3 94  ? 381.394 348.565 470.298 1.00 50.31  ? 94  THR A CA  1 
ATOM 2061 C C   . THR C 3 94  ? 381.091 349.593 471.374 1.00 50.31  ? 94  THR A C   1 
ATOM 2062 O O   . THR C 3 94  ? 381.245 350.792 471.130 1.00 50.31  ? 94  THR A O   1 
ATOM 2063 C CB  . THR C 3 94  ? 380.813 349.027 468.970 1.00 50.31  ? 94  THR A CB  1 
ATOM 2064 O OG1 . THR C 3 94  ? 379.516 349.582 469.194 1.00 50.31  ? 94  THR A OG1 1 
ATOM 2065 C CG2 . THR C 3 94  ? 380.669 347.851 468.039 1.00 50.31  ? 94  THR A CG2 1 
ATOM 2066 N N   . ARG C 3 95  ? 380.670 349.157 472.558 1.00 51.14  ? 95  ARG A N   1 
ATOM 2067 C CA  . ARG C 3 95  ? 380.182 350.057 473.586 1.00 51.14  ? 95  ARG A CA  1 
ATOM 2068 C C   . ARG C 3 95  ? 381.228 350.380 474.639 1.00 51.14  ? 95  ARG A C   1 
ATOM 2069 O O   . ARG C 3 95  ? 380.872 350.793 475.742 1.00 51.14  ? 95  ARG A O   1 
ATOM 2070 C CB  . ARG C 3 95  ? 378.948 349.463 474.250 1.00 51.14  ? 95  ARG A CB  1 
ATOM 2071 C CG  . ARG C 3 95  ? 377.838 349.127 473.300 1.00 51.14  ? 95  ARG A CG  1 
ATOM 2072 C CD  . ARG C 3 95  ? 376.552 348.909 474.049 1.00 51.14  ? 95  ARG A CD  1 
ATOM 2073 N NE  . ARG C 3 95  ? 375.399 349.232 473.222 1.00 51.14  ? 95  ARG A NE  1 
ATOM 2074 C CZ  . ARG C 3 95  ? 374.158 349.335 473.682 1.00 51.14  ? 95  ARG A CZ  1 
ATOM 2075 N NH1 . ARG C 3 95  ? 373.911 349.134 474.968 1.00 51.14  ? 95  ARG A NH1 1 
ATOM 2076 N NH2 . ARG C 3 95  ? 373.164 349.636 472.857 1.00 51.14  ? 95  ARG A NH2 1 
ATOM 2077 N N   . GLN C 3 96  ? 382.506 350.210 474.330 1.00 54.29  ? 96  GLN A N   1 
ATOM 2078 C CA  . GLN C 3 96  ? 383.539 350.528 475.307 1.00 54.29  ? 96  GLN A CA  1 
ATOM 2079 C C   . GLN C 3 96  ? 384.165 351.893 475.049 1.00 54.29  ? 96  GLN A C   1 
ATOM 2080 O O   . GLN C 3 96  ? 384.410 352.652 475.989 1.00 54.29  ? 96  GLN A O   1 
ATOM 2081 C CB  . GLN C 3 96  ? 384.618 349.444 475.300 1.00 54.29  ? 96  GLN A CB  1 
ATOM 2082 C CG  . GLN C 3 96  ? 384.126 348.065 475.697 1.00 54.29  ? 96  GLN A CG  1 
ATOM 2083 C CD  . GLN C 3 96  ? 384.360 347.761 477.158 1.00 54.29  ? 96  GLN A CD  1 
ATOM 2084 O OE1 . GLN C 3 96  ? 385.290 348.280 477.765 1.00 54.29  ? 96  GLN A OE1 1 
ATOM 2085 N NE2 . GLN C 3 96  ? 383.523 346.911 477.728 1.00 54.29  ? 96  GLN A NE2 1 
ATOM 2086 N N   . VAL C 3 97  ? 384.432 352.216 473.792 1.00 53.29  ? 97  VAL A N   1 
ATOM 2087 C CA  . VAL C 3 97  ? 385.108 353.454 473.442 1.00 53.29  ? 97  VAL A CA  1 
ATOM 2088 C C   . VAL C 3 97  ? 384.082 354.484 472.980 1.00 53.29  ? 97  VAL A C   1 
ATOM 2089 O O   . VAL C 3 97  ? 383.162 354.193 472.216 1.00 53.29  ? 97  VAL A O   1 
ATOM 2090 C CB  . VAL C 3 97  ? 386.200 353.180 472.384 1.00 53.29  ? 97  VAL A CB  1 
ATOM 2091 C CG1 . VAL C 3 97  ? 385.650 352.362 471.246 1.00 53.29  ? 97  VAL A CG1 1 
ATOM 2092 C CG2 . VAL C 3 97  ? 386.813 354.459 471.864 1.00 53.29  ? 97  VAL A CG2 1 
ATOM 2093 N N   . ALA C 3 98  ? 384.229 355.714 473.474 1.00 54.87  ? 98  ALA A N   1 
ATOM 2094 C CA  . ALA C 3 98  ? 383.230 356.756 473.296 1.00 54.87  ? 98  ALA A CA  1 
ATOM 2095 C C   . ALA C 3 98  ? 383.210 357.367 471.905 1.00 54.87  ? 98  ALA A C   1 
ATOM 2096 O O   . ALA C 3 98  ? 382.173 357.897 471.500 1.00 54.87  ? 98  ALA A O   1 
ATOM 2097 C CB  . ALA C 3 98  ? 383.455 357.871 474.313 1.00 54.87  ? 98  ALA A CB  1 
ATOM 2098 N N   . GLN C 3 99  ? 384.308 357.323 471.162 1.00 53.06  ? 99  GLN A N   1 
ATOM 2099 C CA  . GLN C 3 99  ? 384.308 357.938 469.844 1.00 53.06  ? 99  GLN A CA  1 
ATOM 2100 C C   . GLN C 3 99  ? 383.766 357.027 468.760 1.00 53.06  ? 99  GLN A C   1 
ATOM 2101 O O   . GLN C 3 99  ? 383.288 357.522 467.737 1.00 53.06  ? 99  GLN A O   1 
ATOM 2102 C CB  . GLN C 3 99  ? 385.718 358.391 469.463 1.00 53.06  ? 99  GLN A CB  1 
ATOM 2103 C CG  . GLN C 3 99  ? 386.163 359.653 470.170 1.00 53.06  ? 99  GLN A CG  1 
ATOM 2104 C CD  . GLN C 3 99  ? 385.626 360.916 469.528 1.00 53.06  ? 99  GLN A CD  1 
ATOM 2105 O OE1 . GLN C 3 99  ? 384.999 360.876 468.470 1.00 53.06  ? 99  GLN A OE1 1 
ATOM 2106 N NE2 . GLN C 3 99  ? 385.875 362.050 470.168 1.00 53.06  ? 99  GLN A NE2 1 
ATOM 2107 N N   . LEU C 3 100 ? 383.832 355.714 468.948 1.00 50.47  ? 100 LEU A N   1 
ATOM 2108 C CA  . LEU C 3 100 ? 383.201 354.805 468.004 1.00 50.47  ? 100 LEU A CA  1 
ATOM 2109 C C   . LEU C 3 100 ? 381.734 354.603 468.334 1.00 50.47  ? 100 LEU A C   1 
ATOM 2110 O O   . LEU C 3 100 ? 380.923 354.375 467.433 1.00 50.47  ? 100 LEU A O   1 
ATOM 2111 C CB  . LEU C 3 100 ? 383.938 353.468 468.001 1.00 50.47  ? 100 LEU A CB  1 
ATOM 2112 C CG  . LEU C 3 100 ? 383.401 352.273 467.216 1.00 50.47  ? 100 LEU A CG  1 
ATOM 2113 C CD1 . LEU C 3 100 ? 383.197 352.625 465.761 1.00 50.47  ? 100 LEU A CD1 1 
ATOM 2114 C CD2 . LEU C 3 100 ? 384.348 351.098 467.351 1.00 50.47  ? 100 LEU A CD2 1 
ATOM 2115 N N   . ARG C 3 101 ? 381.376 354.715 469.612 1.00 49.35  ? 101 ARG A N   1 
ATOM 2116 C CA  . ARG C 3 101 ? 380.004 354.470 470.034 1.00 49.35  ? 101 ARG A CA  1 
ATOM 2117 C C   . ARG C 3 101 ? 379.071 355.572 469.562 1.00 49.35  ? 101 ARG A C   1 
ATOM 2118 O O   . ARG C 3 101 ? 377.899 355.317 469.279 1.00 49.35  ? 101 ARG A O   1 
ATOM 2119 C CB  . ARG C 3 101 ? 379.951 354.342 471.551 1.00 49.35  ? 101 ARG A CB  1 
ATOM 2120 C CG  . ARG C 3 101 ? 378.703 353.712 472.079 1.00 49.35  ? 101 ARG A CG  1 
ATOM 2121 C CD  . ARG C 3 101 ? 378.758 353.621 473.577 1.00 49.35  ? 101 ARG A CD  1 
ATOM 2122 N NE  . ARG C 3 101 ? 377.432 353.482 474.152 1.00 49.35  ? 101 ARG A NE  1 
ATOM 2123 C CZ  . ARG C 3 101 ? 377.202 353.367 475.451 1.00 49.35  ? 101 ARG A CZ  1 
ATOM 2124 N NH1 . ARG C 3 101 ? 378.213 353.375 476.301 1.00 49.35  ? 101 ARG A NH1 1 
ATOM 2125 N NH2 . ARG C 3 101 ? 375.965 353.242 475.898 1.00 49.35  ? 101 ARG A NH2 1 
ATOM 2126 N N   . ARG C 3 102 ? 379.570 356.800 469.460 1.00 48.84  ? 102 ARG A N   1 
ATOM 2127 C CA  . ARG C 3 102 ? 378.707 357.903 469.064 1.00 48.84  ? 102 ARG A CA  1 
ATOM 2128 C C   . ARG C 3 102 ? 378.401 357.873 467.575 1.00 48.84  ? 102 ARG A C   1 
ATOM 2129 O O   . ARG C 3 102 ? 377.374 358.406 467.145 1.00 48.84  ? 102 ARG A O   1 
ATOM 2130 C CB  . ARG C 3 102 ? 379.349 359.234 469.441 1.00 48.84  ? 102 ARG A CB  1 
ATOM 2131 C CG  . ARG C 3 102 ? 378.369 360.382 469.559 1.00 48.84  ? 102 ARG A CG  1 
ATOM 2132 C CD  . ARG C 3 102 ? 379.091 361.699 469.518 1.00 48.84  ? 102 ARG A CD  1 
ATOM 2133 N NE  . ARG C 3 102 ? 378.270 362.801 469.991 1.00 48.84  ? 102 ARG A NE  1 
ATOM 2134 C CZ  . ARG C 3 102 ? 377.864 363.800 469.223 1.00 48.84  ? 102 ARG A CZ  1 
ATOM 2135 N NH1 . ARG C 3 102 ? 378.204 363.829 467.947 1.00 48.84  ? 102 ARG A NH1 1 
ATOM 2136 N NH2 . ARG C 3 102 ? 377.123 364.771 469.728 1.00 48.84  ? 102 ARG A NH2 1 
ATOM 2137 N N   . LYS C 3 103 ? 379.265 357.261 466.774 1.00 48.82  ? 103 LYS A N   1 
ATOM 2138 C CA  . LYS C 3 103 ? 378.996 357.192 465.347 1.00 48.82  ? 103 LYS A CA  1 
ATOM 2139 C C   . LYS C 3 103 ? 378.018 356.075 465.026 1.00 48.82  ? 103 LYS A C   1 
ATOM 2140 O O   . LYS C 3 103 ? 377.178 356.219 464.135 1.00 48.82  ? 103 LYS A O   1 
ATOM 2141 C CB  . LYS C 3 103 ? 380.296 357.000 464.575 1.00 48.82  ? 103 LYS A CB  1 
ATOM 2142 C CG  . LYS C 3 103 ? 381.379 357.978 464.962 1.00 48.82  ? 103 LYS A CG  1 
ATOM 2143 C CD  . LYS C 3 103 ? 382.658 357.710 464.212 1.00 48.82  ? 103 LYS A CD  1 
ATOM 2144 C CE  . LYS C 3 103 ? 382.592 358.277 462.815 1.00 48.82  ? 103 LYS A CE  1 
ATOM 2145 N NZ  . LYS C 3 103 ? 383.778 357.891 462.009 1.00 48.82  ? 103 LYS A NZ  1 
ATOM 2146 N N   . LEU C 3 104 ? 378.106 354.961 465.739 1.00 47.78  ? 104 LEU A N   1 
ATOM 2147 C CA  . LEU C 3 104 ? 377.184 353.865 465.504 1.00 47.78  ? 104 LEU A CA  1 
ATOM 2148 C C   . LEU C 3 104 ? 375.812 354.113 466.103 1.00 47.78  ? 104 LEU A C   1 
ATOM 2149 O O   . LEU C 3 104 ? 374.854 353.452 465.696 1.00 47.78  ? 104 LEU A O   1 
ATOM 2150 C CB  . LEU C 3 104 ? 377.754 352.568 466.069 1.00 47.78  ? 104 LEU A CB  1 
ATOM 2151 C CG  . LEU C 3 104 ? 378.977 351.972 465.380 1.00 47.78  ? 104 LEU A CG  1 
ATOM 2152 C CD1 . LEU C 3 104 ? 379.300 350.662 466.002 1.00 47.78  ? 104 LEU A CD1 1 
ATOM 2153 C CD2 . LEU C 3 104 ? 378.738 351.770 463.911 1.00 47.78  ? 104 LEU A CD2 1 
ATOM 2154 N N   . GLU C 3 105 ? 375.687 355.040 467.049 1.00 50.47  ? 105 GLU A N   1 
ATOM 2155 C CA  . GLU C 3 105 ? 374.417 355.328 467.695 1.00 50.47  ? 105 GLU A CA  1 
ATOM 2156 C C   . GLU C 3 105 ? 373.671 356.468 467.028 1.00 50.47  ? 105 GLU A C   1 
ATOM 2157 O O   . GLU C 3 105 ? 372.762 357.039 467.630 1.00 50.47  ? 105 GLU A O   1 
ATOM 2158 C CB  . GLU C 3 105 ? 374.624 355.645 469.172 1.00 50.47  ? 105 GLU A CB  1 
ATOM 2159 C CG  . GLU C 3 105 ? 374.678 354.434 470.059 1.00 50.47  ? 105 GLU A CG  1 
ATOM 2160 C CD  . GLU C 3 105 ? 374.803 354.803 471.522 1.00 50.47  ? 105 GLU A CD  1 
ATOM 2161 O OE1 . GLU C 3 105 ? 374.731 356.009 471.843 1.00 50.47  ? 105 GLU A OE1 1 
ATOM 2162 O OE2 . GLU C 3 105 ? 374.979 353.887 472.354 1.00 50.47  ? 105 GLU A OE2 1 
ATOM 2163 N N   . LEU C 3 106 ? 374.051 356.830 465.812 1.00 46.40  ? 106 LEU A N   1 
ATOM 2164 C CA  . LEU C 3 106 ? 373.206 357.690 465.005 1.00 46.40  ? 106 LEU A CA  1 
ATOM 2165 C C   . LEU C 3 106 ? 372.100 356.920 464.315 1.00 46.40  ? 106 LEU A C   1 
ATOM 2166 O O   . LEU C 3 106 ? 371.182 357.539 463.777 1.00 46.40  ? 106 LEU A O   1 
ATOM 2167 C CB  . LEU C 3 106 ? 374.031 358.416 463.954 1.00 46.40  ? 106 LEU A CB  1 
ATOM 2168 C CG  . LEU C 3 106 ? 374.716 359.683 464.414 1.00 46.40  ? 106 LEU A CG  1 
ATOM 2169 C CD1 . LEU C 3 106 ? 375.786 360.064 463.434 1.00 46.40  ? 106 LEU A CD1 1 
ATOM 2170 C CD2 . LEU C 3 106 ? 373.673 360.749 464.477 1.00 46.40  ? 106 LEU A CD2 1 
ATOM 2171 N N   . PHE C 3 107 ? 372.172 355.597 464.313 1.00 46.23  ? 107 PHE A N   1 
ATOM 2172 C CA  . PHE C 3 107 ? 371.240 354.759 463.586 1.00 46.23  ? 107 PHE A CA  1 
ATOM 2173 C C   . PHE C 3 107 ? 370.734 353.670 464.515 1.00 46.23  ? 107 PHE A C   1 
ATOM 2174 O O   . PHE C 3 107 ? 371.435 353.228 465.425 1.00 46.23  ? 107 PHE A O   1 
ATOM 2175 C CB  . PHE C 3 107 ? 371.901 354.145 462.350 1.00 46.23  ? 107 PHE A CB  1 
ATOM 2176 C CG  . PHE C 3 107 ? 372.722 355.116 461.560 1.00 46.23  ? 107 PHE A CG  1 
ATOM 2177 C CD1 . PHE C 3 107 ? 372.126 355.942 460.632 1.00 46.23  ? 107 PHE A CD1 1 
ATOM 2178 C CD2 . PHE C 3 107 ? 374.088 355.202 461.747 1.00 46.23  ? 107 PHE A CD2 1 
ATOM 2179 C CE1 . PHE C 3 107 ? 372.870 356.835 459.906 1.00 46.23  ? 107 PHE A CE1 1 
ATOM 2180 C CE2 . PHE C 3 107 ? 374.839 356.098 461.028 1.00 46.23  ? 107 PHE A CE2 1 
ATOM 2181 C CZ  . PHE C 3 107 ? 374.229 356.914 460.105 1.00 46.23  ? 107 PHE A CZ  1 
ATOM 2182 N N   . THR C 3 108 ? 369.501 353.236 464.278 1.00 46.56  ? 108 THR A N   1 
ATOM 2183 C CA  . THR C 3 108 ? 368.903 352.228 465.140 1.00 46.56  ? 108 THR A CA  1 
ATOM 2184 C C   . THR C 3 108 ? 369.309 350.818 464.730 1.00 46.56  ? 108 THR A C   1 
ATOM 2185 O O   . THR C 3 108 ? 369.615 349.986 465.587 1.00 46.56  ? 108 THR A O   1 
ATOM 2186 C CB  . THR C 3 108 ? 367.383 352.361 465.130 1.00 46.56  ? 108 THR A CB  1 
ATOM 2187 O OG1 . THR C 3 108 ? 367.028 353.735 465.293 1.00 46.56  ? 108 THR A OG1 1 
ATOM 2188 C CG2 . THR C 3 108 ? 366.785 351.577 466.259 1.00 46.56  ? 108 THR A CG2 1 
ATOM 2189 N N   . TYR C 3 109 ? 369.330 350.532 463.435 1.00 47.93  ? 109 TYR A N   1 
ATOM 2190 C CA  . TYR C 3 109 ? 369.629 349.195 462.948 1.00 47.93  ? 109 TYR A CA  1 
ATOM 2191 C C   . TYR C 3 109 ? 370.832 349.252 462.025 1.00 47.93  ? 109 TYR A C   1 
ATOM 2192 O O   . TYR C 3 109 ? 370.825 349.991 461.038 1.00 47.93  ? 109 TYR A O   1 
ATOM 2193 C CB  . TYR C 3 109 ? 368.420 348.600 462.233 1.00 47.93  ? 109 TYR A CB  1 
ATOM 2194 C CG  . TYR C 3 109 ? 367.201 348.556 463.104 1.00 47.93  ? 109 TYR A CG  1 
ATOM 2195 C CD1 . TYR C 3 109 ? 367.117 347.668 464.161 1.00 47.93  ? 109 TYR A CD1 1 
ATOM 2196 C CD2 . TYR C 3 109 ? 366.140 349.416 462.883 1.00 47.93  ? 109 TYR A CD2 1 
ATOM 2197 C CE1 . TYR C 3 109 ? 366.007 347.635 464.967 1.00 47.93  ? 109 TYR A CE1 1 
ATOM 2198 C CE2 . TYR C 3 109 ? 365.027 349.392 463.686 1.00 47.93  ? 109 TYR A CE2 1 
ATOM 2199 C CZ  . TYR C 3 109 ? 364.967 348.502 464.722 1.00 47.93  ? 109 TYR A CZ  1 
ATOM 2200 O OH  . TYR C 3 109 ? 363.855 348.478 465.519 1.00 47.93  ? 109 TYR A OH  1 
ATOM 2201 N N   . LEU C 3 110 ? 371.856 348.471 462.341 1.00 48.04  ? 110 LEU A N   1 
ATOM 2202 C CA  . LEU C 3 110 ? 373.049 348.366 461.524 1.00 48.04  ? 110 LEU A CA  1 
ATOM 2203 C C   . LEU C 3 110 ? 373.254 346.925 461.088 1.00 48.04  ? 110 LEU A C   1 
ATOM 2204 O O   . LEU C 3 110 ? 372.767 345.988 461.719 1.00 48.04  ? 110 LEU A O   1 
ATOM 2205 C CB  . LEU C 3 110 ? 374.283 348.846 462.282 1.00 48.04  ? 110 LEU A CB  1 
ATOM 2206 C CG  . LEU C 3 110 ? 374.394 350.342 462.523 1.00 48.04  ? 110 LEU A CG  1 
ATOM 2207 C CD1 . LEU C 3 110 ? 375.192 350.583 463.773 1.00 48.04  ? 110 LEU A CD1 1 
ATOM 2208 C CD2 . LEU C 3 110 ? 375.052 351.005 461.342 1.00 48.04  ? 110 LEU A CD2 1 
ATOM 2209 N N   . ARG C 3 111 ? 374.001 346.758 460.005 1.00 47.56  ? 111 ARG A N   1 
ATOM 2210 C CA  . ARG C 3 111 ? 374.309 345.430 459.488 1.00 47.56  ? 111 ARG A CA  1 
ATOM 2211 C C   . ARG C 3 111 ? 375.633 345.536 458.753 1.00 47.56  ? 111 ARG A C   1 
ATOM 2212 O O   . ARG C 3 111 ? 375.705 346.188 457.710 1.00 47.56  ? 111 ARG A O   1 
ATOM 2213 C CB  . ARG C 3 111 ? 373.209 344.942 458.568 1.00 47.56  ? 111 ARG A CB  1 
ATOM 2214 C CG  . ARG C 3 111 ? 373.551 343.687 457.827 1.00 47.56  ? 111 ARG A CG  1 
ATOM 2215 C CD  . ARG C 3 111 ? 372.541 343.403 456.750 1.00 47.56  ? 111 ARG A CD  1 
ATOM 2216 N NE  . ARG C 3 111 ? 372.756 342.094 456.152 1.00 47.56  ? 111 ARG A NE  1 
ATOM 2217 C CZ  . ARG C 3 111 ? 372.046 341.020 456.460 1.00 47.56  ? 111 ARG A CZ  1 
ATOM 2218 N NH1 . ARG C 3 111 ? 371.077 341.110 457.353 1.00 47.56  ? 111 ARG A NH1 1 
ATOM 2219 N NH2 . ARG C 3 111 ? 372.299 339.862 455.875 1.00 47.56  ? 111 ARG A NH2 1 
ATOM 2220 N N   . PHE C 3 112 ? 376.674 344.912 459.292 1.00 46.02  ? 112 PHE A N   1 
ATOM 2221 C CA  . PHE C 3 112 ? 378.001 345.071 458.727 1.00 46.02  ? 112 PHE A CA  1 
ATOM 2222 C C   . PHE C 3 112 ? 378.786 343.785 458.903 1.00 46.02  ? 112 PHE A C   1 
ATOM 2223 O O   . PHE C 3 112 ? 378.499 342.986 459.794 1.00 46.02  ? 112 PHE A O   1 
ATOM 2224 C CB  . PHE C 3 112 ? 378.754 346.247 459.369 1.00 46.02  ? 112 PHE A CB  1 
ATOM 2225 C CG  . PHE C 3 112 ? 378.749 346.247 460.875 1.00 46.02  ? 112 PHE A CG  1 
ATOM 2226 C CD1 . PHE C 3 112 ? 379.746 345.616 461.587 1.00 46.02  ? 112 PHE A CD1 1 
ATOM 2227 C CD2 . PHE C 3 112 ? 377.770 346.917 461.579 1.00 46.02  ? 112 PHE A CD2 1 
ATOM 2228 C CE1 . PHE C 3 112 ? 379.751 345.626 462.963 1.00 46.02  ? 112 PHE A CE1 1 
ATOM 2229 C CE2 . PHE C 3 112 ? 377.772 346.925 462.958 1.00 46.02  ? 112 PHE A CE2 1 
ATOM 2230 C CZ  . PHE C 3 112 ? 378.765 346.280 463.645 1.00 46.02  ? 112 PHE A CZ  1 
ATOM 2231 N N   . ASP C 3 113 ? 379.780 343.595 458.042 1.00 50.84  ? 113 ASP A N   1 
ATOM 2232 C CA  . ASP C 3 113 ? 380.762 342.544 458.237 1.00 50.84  ? 113 ASP A CA  1 
ATOM 2233 C C   . ASP C 3 113 ? 381.765 343.000 459.286 1.00 50.84  ? 113 ASP A C   1 
ATOM 2234 O O   . ASP C 3 113 ? 381.798 344.164 459.679 1.00 50.84  ? 113 ASP A O   1 
ATOM 2235 C CB  . ASP C 3 113 ? 381.467 342.218 456.928 1.00 50.84  ? 113 ASP A CB  1 
ATOM 2236 C CG  . ASP C 3 113 ? 380.523 341.701 455.878 1.00 50.84  ? 113 ASP A CG  1 
ATOM 2237 O OD1 . ASP C 3 113 ? 379.482 341.124 456.243 1.00 50.84  ? 113 ASP A OD1 1 
ATOM 2238 O OD2 . ASP C 3 113 ? 380.818 341.872 454.680 1.00 50.84  ? 113 ASP A OD2 1 
ATOM 2239 N N   . LEU C 3 114 ? 382.621 342.098 459.736 1.00 48.04  ? 114 LEU A N   1 
ATOM 2240 C CA  . LEU C 3 114 ? 383.554 342.467 460.784 1.00 48.04  ? 114 LEU A CA  1 
ATOM 2241 C C   . LEU C 3 114 ? 384.951 342.031 460.378 1.00 48.04  ? 114 LEU A C   1 
ATOM 2242 O O   . LEU C 3 114 ? 385.123 341.040 459.669 1.00 48.04  ? 114 LEU A O   1 
ATOM 2243 C CB  . LEU C 3 114 ? 383.139 341.847 462.120 1.00 48.04  ? 114 LEU A CB  1 
ATOM 2244 C CG  . LEU C 3 114 ? 383.787 342.435 463.357 1.00 48.04  ? 114 LEU A CG  1 
ATOM 2245 C CD1 . LEU C 3 114 ? 383.399 343.874 463.362 1.00 48.04  ? 114 LEU A CD1 1 
ATOM 2246 C CD2 . LEU C 3 114 ? 383.296 341.750 464.601 1.00 48.04  ? 114 LEU A CD2 1 
ATOM 2247 N N   . GLU C 3 115 ? 385.949 342.777 460.839 1.00 48.68  ? 115 GLU A N   1 
ATOM 2248 C CA  . GLU C 3 115 ? 387.327 342.553 460.422 1.00 48.68  ? 115 GLU A CA  1 
ATOM 2249 C C   . GLU C 3 115 ? 388.255 343.005 461.533 1.00 48.68  ? 115 GLU A C   1 
ATOM 2250 O O   . GLU C 3 115 ? 388.244 344.180 461.903 1.00 48.68  ? 115 GLU A O   1 
ATOM 2251 C CB  . GLU C 3 115 ? 387.626 343.310 459.142 1.00 48.68  ? 115 GLU A CB  1 
ATOM 2252 C CG  . GLU C 3 115 ? 388.926 342.939 458.523 1.00 48.68  ? 115 GLU A CG  1 
ATOM 2253 C CD  . GLU C 3 115 ? 389.530 344.088 457.775 1.00 48.68  ? 115 GLU A CD  1 
ATOM 2254 O OE1 . GLU C 3 115 ? 390.156 344.947 458.428 1.00 48.68  ? 115 GLU A OE1 1 
ATOM 2255 O OE2 . GLU C 3 115 ? 389.380 344.141 456.539 1.00 48.68  ? 115 GLU A OE2 1 
ATOM 2256 N N   . LEU C 3 116 ? 389.054 342.087 462.058 1.00 42.73  ? 116 LEU A N   1 
ATOM 2257 C CA  . LEU C 3 116 ? 389.858 342.352 463.238 1.00 42.73  ? 116 LEU A CA  1 
ATOM 2258 C C   . LEU C 3 116 ? 391.324 342.140 462.911 1.00 42.73  ? 116 LEU A C   1 
ATOM 2259 O O   . LEU C 3 116 ? 391.659 341.311 462.068 1.00 42.73  ? 116 LEU A O   1 
ATOM 2260 C CB  . LEU C 3 116 ? 389.448 341.458 464.409 1.00 42.73  ? 116 LEU A CB  1 
ATOM 2261 C CG  . LEU C 3 116 ? 388.080 341.732 465.031 1.00 42.73  ? 116 LEU A CG  1 
ATOM 2262 C CD1 . LEU C 3 116 ? 387.025 340.867 464.387 1.00 42.73  ? 116 LEU A CD1 1 
ATOM 2263 C CD2 . LEU C 3 116 ? 388.099 341.492 466.497 1.00 42.73  ? 116 LEU A CD2 1 
ATOM 2264 N N   . THR C 3 117 ? 392.194 342.904 463.568 1.00 37.98  ? 117 THR A N   1 
ATOM 2265 C CA  . THR C 3 117 ? 393.636 342.773 463.411 1.00 37.98  ? 117 THR A CA  1 
ATOM 2266 C C   . THR C 3 117 ? 394.287 342.938 464.772 1.00 37.98  ? 117 THR A C   1 
ATOM 2267 O O   . THR C 3 117 ? 393.887 343.808 465.546 1.00 37.98  ? 117 THR A O   1 
ATOM 2268 C CB  . THR C 3 117 ? 394.193 343.802 462.438 1.00 37.98  ? 117 THR A CB  1 
ATOM 2269 O OG1 . THR C 3 117 ? 393.304 343.944 461.328 1.00 37.98  ? 117 THR A OG1 1 
ATOM 2270 C CG2 . THR C 3 117 ? 395.539 343.357 461.924 1.00 37.98  ? 117 THR A CG2 1 
ATOM 2271 N N   . PHE C 3 118 ? 395.279 342.105 465.062 1.00 37.89  ? 118 PHE A N   1 
ATOM 2272 C CA  . PHE C 3 118 ? 395.859 341.991 466.392 1.00 37.89  ? 118 PHE A CA  1 
ATOM 2273 C C   . PHE C 3 118 ? 397.338 342.330 466.341 1.00 37.89  ? 118 PHE A C   1 
ATOM 2274 O O   . PHE C 3 118 ? 398.101 341.665 465.640 1.00 37.89  ? 118 PHE A O   1 
ATOM 2275 C CB  . PHE C 3 118 ? 395.689 340.577 466.953 1.00 37.89  ? 118 PHE A CB  1 
ATOM 2276 C CG  . PHE C 3 118 ? 394.296 340.040 466.855 1.00 37.89  ? 118 PHE A CG  1 
ATOM 2277 C CD1 . PHE C 3 118 ? 393.387 340.265 467.864 1.00 37.89  ? 118 PHE A CD1 1 
ATOM 2278 C CD2 . PHE C 3 118 ? 393.905 339.290 465.767 1.00 37.89  ? 118 PHE A CD2 1 
ATOM 2279 C CE1 . PHE C 3 118 ? 392.109 339.772 467.773 1.00 37.89  ? 118 PHE A CE1 1 
ATOM 2280 C CE2 . PHE C 3 118 ? 392.637 338.799 465.670 1.00 37.89  ? 118 PHE A CE2 1 
ATOM 2281 C CZ  . PHE C 3 118 ? 391.736 339.039 466.675 1.00 37.89  ? 118 PHE A CZ  1 
ATOM 2282 N N   . VAL C 3 119 ? 397.747 343.335 467.100 1.00 38.48  ? 119 VAL A N   1 
ATOM 2283 C CA  . VAL C 3 119 ? 399.145 343.734 467.177 1.00 38.48  ? 119 VAL A CA  1 
ATOM 2284 C C   . VAL C 3 119 ? 399.681 343.231 468.505 1.00 38.48  ? 119 VAL A C   1 
ATOM 2285 O O   . VAL C 3 119 ? 399.374 343.792 469.562 1.00 38.48  ? 119 VAL A O   1 
ATOM 2286 C CB  . VAL C 3 119 ? 399.313 345.250 467.039 1.00 38.48  ? 119 VAL A CB  1 
ATOM 2287 C CG1 . VAL C 3 119 ? 400.758 345.628 467.193 1.00 38.48  ? 119 VAL A CG1 1 
ATOM 2288 C CG2 . VAL C 3 119 ? 398.801 345.698 465.695 1.00 38.48  ? 119 VAL A CG2 1 
ATOM 2289 N N   . ILE C 3 120 ? 400.472 342.165 468.460 1.00 39.04  ? 120 ILE A N   1 
ATOM 2290 C CA  . ILE C 3 120 ? 400.979 341.507 469.656 1.00 39.04  ? 120 ILE A CA  1 
ATOM 2291 C C   . ILE C 3 120 ? 402.470 341.773 469.753 1.00 39.04  ? 120 ILE A C   1 
ATOM 2292 O O   . ILE C 3 120 ? 403.214 341.537 468.795 1.00 39.04  ? 120 ILE A O   1 
ATOM 2293 C CB  . ILE C 3 120 ? 400.700 340.001 469.635 1.00 39.04  ? 120 ILE A CB  1 
ATOM 2294 C CG1 . ILE C 3 120 ? 399.336 339.729 469.020 1.00 39.04  ? 120 ILE A CG1 1 
ATOM 2295 C CG2 . ILE C 3 120 ? 400.747 339.455 471.023 1.00 39.04  ? 120 ILE A CG2 1 
ATOM 2296 C CD1 . ILE C 3 120 ? 399.090 338.286 468.710 1.00 39.04  ? 120 ILE A CD1 1 
ATOM 2297 N N   . THR C 3 121 ? 402.905 342.270 470.904 1.00 45.84  ? 121 THR A N   1 
ATOM 2298 C CA  . THR C 3 121 ? 404.312 342.445 471.210 1.00 45.84  ? 121 THR A CA  1 
ATOM 2299 C C   . THR C 3 121 ? 404.648 341.597 472.425 1.00 45.84  ? 121 THR A C   1 
ATOM 2300 O O   . THR C 3 121 ? 403.837 340.793 472.877 1.00 45.84  ? 121 THR A O   1 
ATOM 2301 C CB  . THR C 3 121 ? 404.661 343.898 471.501 1.00 45.84  ? 121 THR A CB  1 
ATOM 2302 O OG1 . THR C 3 121 ? 404.077 344.273 472.746 1.00 45.84  ? 121 THR A OG1 1 
ATOM 2303 C CG2 . THR C 3 121 ? 404.114 344.804 470.422 1.00 45.84  ? 121 THR A CG2 1 
ATOM 2304 N N   . SER C 3 122 ? 405.851 341.777 472.955 1.00 52.42  ? 122 SER A N   1 
ATOM 2305 C CA  . SER C 3 122 ? 406.304 341.009 474.103 1.00 52.42  ? 122 SER A CA  1 
ATOM 2306 C C   . SER C 3 122 ? 407.273 341.825 474.945 1.00 52.42  ? 122 SER A C   1 
ATOM 2307 O O   . SER C 3 122 ? 407.656 342.941 474.594 1.00 52.42  ? 122 SER A O   1 
ATOM 2308 C CB  . SER C 3 122 ? 406.971 339.705 473.661 1.00 52.42  ? 122 SER A CB  1 
ATOM 2309 O OG  . SER C 3 122 ? 406.005 338.718 473.361 1.00 52.42  ? 122 SER A OG  1 
ATOM 2310 N N   . ALA C 3 123 ? 407.675 341.241 476.071 1.00 59.51  ? 123 ALA A N   1 
ATOM 2311 C CA  . ALA C 3 123 ? 408.636 341.855 476.973 1.00 59.51  ? 123 ALA A CA  1 
ATOM 2312 C C   . ALA C 3 123 ? 409.337 340.757 477.751 1.00 59.51  ? 123 ALA A C   1 
ATOM 2313 O O   . ALA C 3 123 ? 408.784 339.672 477.931 1.00 59.51  ? 123 ALA A O   1 
ATOM 2314 C CB  . ALA C 3 123 ? 407.965 342.830 477.939 1.00 59.51  ? 123 ALA A CB  1 
ATOM 2315 N N   . GLN C 3 124 ? 410.552 341.034 478.201 1.00 65.10  ? 124 GLN A N   1 
ATOM 2316 C CA  . GLN C 3 124 ? 411.317 340.077 478.985 1.00 65.10  ? 124 GLN A CA  1 
ATOM 2317 C C   . GLN C 3 124 ? 411.259 340.476 480.453 1.00 65.10  ? 124 GLN A C   1 
ATOM 2318 O O   . GLN C 3 124 ? 412.006 341.355 480.892 1.00 65.10  ? 124 GLN A O   1 
ATOM 2319 C CB  . GLN C 3 124 ? 412.762 340.014 478.495 1.00 65.10  ? 124 GLN A CB  1 
ATOM 2320 C CG  . GLN C 3 124 ? 413.655 339.058 479.268 1.00 65.10  ? 124 GLN A CG  1 
ATOM 2321 C CD  . GLN C 3 124 ? 415.116 339.208 478.906 1.00 65.10  ? 124 GLN A CD  1 
ATOM 2322 O OE1 . GLN C 3 124 ? 415.456 339.736 477.851 1.00 65.10  ? 124 GLN A OE1 1 
ATOM 2323 N NE2 . GLN C 3 124 ? 415.990 338.746 479.786 1.00 65.10  ? 124 GLN A NE2 1 
ATOM 2324 N N   . GLN C 3 125 ? 410.364 339.849 481.199 1.00 67.41  ? 125 GLN A N   1 
ATOM 2325 C CA  . GLN C 3 125 ? 410.251 340.107 482.621 1.00 67.41  ? 125 GLN A CA  1 
ATOM 2326 C C   . GLN C 3 125 ? 411.463 339.535 483.349 1.00 67.41  ? 125 GLN A C   1 
ATOM 2327 O O   . GLN C 3 125 ? 412.021 338.523 482.923 1.00 67.41  ? 125 GLN A O   1 
ATOM 2328 C CB  . GLN C 3 125 ? 408.961 339.500 483.154 1.00 67.41  ? 125 GLN A CB  1 
ATOM 2329 C CG  . GLN C 3 125 ? 407.724 340.190 482.639 1.00 67.41  ? 125 GLN A CG  1 
ATOM 2330 C CD  . GLN C 3 125 ? 407.808 341.691 482.764 1.00 67.41  ? 125 GLN A CD  1 
ATOM 2331 O OE1 . GLN C 3 125 ? 407.750 342.410 481.769 1.00 67.41  ? 125 GLN A OE1 1 
ATOM 2332 N NE2 . GLN C 3 125 ? 407.939 342.177 483.991 1.00 67.41  ? 125 GLN A NE2 1 
ATOM 2333 N N   . PRO C 3 126 ? 411.914 340.191 484.443 1.00 71.05  ? 126 PRO A N   1 
ATOM 2334 C CA  . PRO C 3 126 ? 413.189 339.805 485.070 1.00 71.05  ? 126 PRO A CA  1 
ATOM 2335 C C   . PRO C 3 126 ? 413.209 338.417 485.691 1.00 71.05  ? 126 PRO A C   1 
ATOM 2336 O O   . PRO C 3 126 ? 412.436 338.111 486.601 1.00 71.05  ? 126 PRO A O   1 
ATOM 2337 C CB  . PRO C 3 126 ? 413.392 340.884 486.141 1.00 71.05  ? 126 PRO A CB  1 
ATOM 2338 C CG  . PRO C 3 126 ? 412.064 341.507 486.330 1.00 71.05  ? 126 PRO A CG  1 
ATOM 2339 C CD  . PRO C 3 126 ? 411.401 341.449 485.006 1.00 71.05  ? 126 PRO A CD  1 
ATOM 2340 N N   . SER C 3 127 ? 414.105 337.576 485.184 1.00 79.89  ? 127 SER A N   1 
ATOM 2341 C CA  . SER C 3 127 ? 414.300 336.215 485.655 1.00 79.89  ? 127 SER A CA  1 
ATOM 2342 C C   . SER C 3 127 ? 415.376 336.196 486.736 1.00 79.89  ? 127 SER A C   1 
ATOM 2343 O O   . SER C 3 127 ? 415.750 337.231 487.289 1.00 79.89  ? 127 SER A O   1 
ATOM 2344 C CB  . SER C 3 127 ? 414.668 335.306 484.489 1.00 79.89  ? 127 SER A CB  1 
ATOM 2345 O OG  . SER C 3 127 ? 414.750 333.954 484.904 1.00 79.89  ? 127 SER A OG  1 
ATOM 2346 N N   . THR C 3 128 ? 415.883 335.007 487.061 1.00 86.46  ? 128 THR A N   1 
ATOM 2347 C CA  . THR C 3 128 ? 416.935 334.932 488.066 1.00 86.46  ? 128 THR A CA  1 
ATOM 2348 C C   . THR C 3 128 ? 418.319 335.217 487.477 1.00 86.46  ? 128 THR A C   1 
ATOM 2349 O O   . THR C 3 128 ? 418.901 336.270 487.760 1.00 86.46  ? 128 THR A O   1 
ATOM 2350 C CB  . THR C 3 128 ? 416.870 333.582 488.804 1.00 86.46  ? 128 THR A CB  1 
ATOM 2351 O OG1 . THR C 3 128 ? 418.050 333.390 489.595 1.00 86.46  ? 128 THR A OG1 1 
ATOM 2352 C CG2 . THR C 3 128 ? 416.577 332.377 487.884 1.00 86.46  ? 128 THR A CG2 1 
ATOM 2353 N N   . ALA C 3 129 ? 418.832 334.340 486.610 1.00 90.13  ? 129 ALA A N   1 
ATOM 2354 C CA  . ALA C 3 129 ? 420.212 334.408 486.117 1.00 90.13  ? 129 ALA A CA  1 
ATOM 2355 C C   . ALA C 3 129 ? 420.398 333.396 484.989 1.00 90.13  ? 129 ALA A C   1 
ATOM 2356 O O   . ALA C 3 129 ? 419.441 332.754 484.537 1.00 90.13  ? 129 ALA A O   1 
ATOM 2357 C CB  . ALA C 3 129 ? 421.229 334.141 487.232 1.00 90.13  ? 129 ALA A CB  1 
ATOM 2358 N N   . SER C 3 130 ? 421.656 333.273 484.546 1.00 93.07  ? 130 SER A N   1 
ATOM 2359 C CA  . SER C 3 130 ? 422.192 332.151 483.767 1.00 93.07  ? 130 SER A CA  1 
ATOM 2360 C C   . SER C 3 130 ? 421.583 332.030 482.366 1.00 93.07  ? 130 SER A C   1 
ATOM 2361 O O   . SER C 3 130 ? 420.903 331.055 482.037 1.00 93.07  ? 130 SER A O   1 
ATOM 2362 C CB  . SER C 3 130 ? 422.047 330.837 484.544 1.00 93.07  ? 130 SER A CB  1 
ATOM 2363 O OG  . SER C 3 130 ? 423.046 330.724 485.541 1.00 93.07  ? 130 SER A OG  1 
ATOM 2364 N N   . SER C 3 131 ? 421.865 333.048 481.544 1.00 90.13  ? 131 SER A N   1 
ATOM 2365 C CA  . SER C 3 131 ? 421.859 332.962 480.076 1.00 90.13  ? 131 SER A CA  1 
ATOM 2366 C C   . SER C 3 131 ? 420.476 332.625 479.509 1.00 90.13  ? 131 SER A C   1 
ATOM 2367 O O   . SER C 3 131 ? 420.218 331.528 479.017 1.00 90.13  ? 131 SER A O   1 
ATOM 2368 C CB  . SER C 3 131 ? 422.906 331.952 479.594 1.00 90.13  ? 131 SER A CB  1 
ATOM 2369 O OG  . SER C 3 131 ? 424.184 332.555 479.484 1.00 90.13  ? 131 SER A OG  1 
ATOM 2370 N N   . VAL C 3 132 ? 419.575 333.595 479.639 1.00 83.60  ? 132 VAL A N   1 
ATOM 2371 C CA  . VAL C 3 132 ? 418.282 333.505 478.973 1.00 83.60  ? 132 VAL A CA  1 
ATOM 2372 C C   . VAL C 3 132 ? 418.478 333.589 477.466 1.00 83.60  ? 132 VAL A C   1 
ATOM 2373 O O   . VAL C 3 132 ? 418.980 334.590 476.944 1.00 83.60  ? 132 VAL A O   1 
ATOM 2374 C CB  . VAL C 3 132 ? 417.338 334.607 479.456 1.00 83.60  ? 132 VAL A CB  1 
ATOM 2375 C CG1 . VAL C 3 132 ? 415.946 334.343 478.938 1.00 83.60  ? 132 VAL A CG1 1 
ATOM 2376 C CG2 . VAL C 3 132 ? 417.349 334.678 480.961 1.00 83.60  ? 132 VAL A CG2 1 
ATOM 2377 N N   . ASP C 3 133 ? 418.083 332.534 476.761 1.00 83.24  ? 133 ASP A N   1 
ATOM 2378 C CA  . ASP C 3 133 ? 418.026 332.527 475.303 1.00 83.24  ? 133 ASP A CA  1 
ATOM 2379 C C   . ASP C 3 133 ? 416.759 331.757 474.962 1.00 83.24  ? 133 ASP A C   1 
ATOM 2380 O O   . ASP C 3 133 ? 416.637 330.582 475.319 1.00 83.24  ? 133 ASP A O   1 
ATOM 2381 C CB  . ASP C 3 133 ? 419.272 331.872 474.700 1.00 83.24  ? 133 ASP A CB  1 
ATOM 2382 C CG  . ASP C 3 133 ? 419.348 331.972 473.164 1.00 83.24  ? 133 ASP A CG  1 
ATOM 2383 O OD1 . ASP C 3 133 ? 418.328 331.939 472.441 1.00 83.24  ? 133 ASP A OD1 1 
ATOM 2384 O OD2 . ASP C 3 133 ? 420.487 332.072 472.664 1.00 83.24  ? 133 ASP A OD2 1 
ATOM 2385 N N   . ALA C 3 134 ? 415.823 332.409 474.280 1.00 71.97  ? 134 ALA A N   1 
ATOM 2386 C CA  . ALA C 3 134 ? 414.562 331.756 473.993 1.00 71.97  ? 134 ALA A CA  1 
ATOM 2387 C C   . ALA C 3 134 ? 414.285 331.743 472.498 1.00 71.97  ? 134 ALA A C   1 
ATOM 2388 O O   . ALA C 3 134 ? 414.681 332.664 471.780 1.00 71.97  ? 134 ALA A O   1 
ATOM 2389 C CB  . ALA C 3 134 ? 413.403 332.451 474.713 1.00 71.97  ? 134 ALA A CB  1 
ATOM 2390 N N   . PRO C 3 135 ? 413.612 330.714 472.002 1.00 63.73  ? 135 PRO A N   1 
ATOM 2391 C CA  . PRO C 3 135 ? 413.142 330.740 470.611 1.00 63.73  ? 135 PRO A CA  1 
ATOM 2392 C C   . PRO C 3 135 ? 411.936 331.647 470.426 1.00 63.73  ? 135 PRO A C   1 
ATOM 2393 O O   . PRO C 3 135 ? 411.476 332.275 471.383 1.00 63.73  ? 135 PRO A O   1 
ATOM 2394 C CB  . PRO C 3 135 ? 412.789 329.274 470.335 1.00 63.73  ? 135 PRO A CB  1 
ATOM 2395 C CG  . PRO C 3 135 ? 413.515 328.494 471.388 1.00 63.73  ? 135 PRO A CG  1 
ATOM 2396 C CD  . PRO C 3 135 ? 413.520 329.368 472.586 1.00 63.73  ? 135 PRO A CD  1 
ATOM 2397 N N   . VAL C 3 136 ? 411.412 331.714 469.200 1.00 57.16  ? 136 VAL A N   1 
ATOM 2398 C CA  . VAL C 3 136 ? 410.294 332.604 468.907 1.00 57.16  ? 136 VAL A CA  1 
ATOM 2399 C C   . VAL C 3 136 ? 409.023 332.091 469.569 1.00 57.16  ? 136 VAL A C   1 
ATOM 2400 O O   . VAL C 3 136 ? 408.851 330.889 469.795 1.00 57.16  ? 136 VAL A O   1 
ATOM 2401 C CB  . VAL C 3 136 ? 410.104 332.749 467.388 1.00 57.16  ? 136 VAL A CB  1 
ATOM 2402 C CG1 . VAL C 3 136 ? 411.137 333.679 466.825 1.00 57.16  ? 136 VAL A CG1 1 
ATOM 2403 C CG2 . VAL C 3 136 ? 410.220 331.404 466.732 1.00 57.16  ? 136 VAL A CG2 1 
ATOM 2404 N N   . GLN C 3 137 ? 408.125 333.013 469.889 1.00 52.83  ? 137 GLN A N   1 
ATOM 2405 C CA  . GLN C 3 137 ? 406.911 332.697 470.621 1.00 52.83  ? 137 GLN A CA  1 
ATOM 2406 C C   . GLN C 3 137 ? 405.730 332.597 469.672 1.00 52.83  ? 137 GLN A C   1 
ATOM 2407 O O   . GLN C 3 137 ? 405.629 333.347 468.703 1.00 52.83  ? 137 GLN A O   1 
ATOM 2408 C CB  . GLN C 3 137 ? 406.630 333.756 471.680 1.00 52.83  ? 137 GLN A CB  1 
ATOM 2409 C CG  . GLN C 3 137 ? 407.728 333.899 472.691 1.00 52.83  ? 137 GLN A CG  1 
ATOM 2410 C CD  . GLN C 3 137 ? 407.833 332.698 473.585 1.00 52.83  ? 137 GLN A CD  1 
ATOM 2411 O OE1 . GLN C 3 137 ? 408.805 331.950 473.527 1.00 52.83  ? 137 GLN A OE1 1 
ATOM 2412 N NE2 . GLN C 3 137 ? 406.831 332.500 474.422 1.00 52.83  ? 137 GLN A NE2 1 
ATOM 2413 N N   . THR C 3 138 ? 404.830 331.666 469.965 1.00 48.50  ? 138 THR A N   1 
ATOM 2414 C CA  . THR C 3 138 ? 403.637 331.451 469.164 1.00 48.50  ? 138 THR A CA  1 
ATOM 2415 C C   . THR C 3 138 ? 402.417 331.679 470.036 1.00 48.50  ? 138 THR A C   1 
ATOM 2416 O O   . THR C 3 138 ? 402.352 331.186 471.164 1.00 48.50  ? 138 THR A O   1 
ATOM 2417 C CB  . THR C 3 138 ? 403.596 330.038 468.577 1.00 48.50  ? 138 THR A CB  1 
ATOM 2418 O OG1 . THR C 3 138 ? 404.899 329.662 468.124 1.00 48.50  ? 138 THR A OG1 1 
ATOM 2419 C CG2 . THR C 3 138 ? 402.635 329.973 467.419 1.00 48.50  ? 138 THR A CG2 1 
ATOM 2420 N N   . HIS C 3 139 ? 401.454 332.430 469.511 1.00 43.98  ? 139 HIS A N   1 
ATOM 2421 C CA  . HIS C 3 139 ? 400.251 332.790 470.239 1.00 43.98  ? 139 HIS A CA  1 
ATOM 2422 C C   . HIS C 3 139 ? 399.041 332.150 469.577 1.00 43.98  ? 139 HIS A C   1 
ATOM 2423 O O   . HIS C 3 139 ? 399.062 331.842 468.386 1.00 43.98  ? 139 HIS A O   1 
ATOM 2424 C CB  . HIS C 3 139 ? 400.069 334.304 470.290 1.00 43.98  ? 139 HIS A CB  1 
ATOM 2425 C CG  . HIS C 3 139 ? 401.245 335.041 470.848 1.00 43.98  ? 139 HIS A CG  1 
ATOM 2426 N ND1 . HIS C 3 139 ? 401.249 335.581 472.114 1.00 43.98  ? 139 HIS A ND1 1 
ATOM 2427 C CD2 . HIS C 3 139 ? 402.445 335.349 470.306 1.00 43.98  ? 139 HIS A CD2 1 
ATOM 2428 C CE1 . HIS C 3 139 ? 402.406 336.176 472.334 1.00 43.98  ? 139 HIS A CE1 1 
ATOM 2429 N NE2 . HIS C 3 139 ? 403.150 336.050 471.252 1.00 43.98  ? 139 HIS A NE2 1 
ATOM 2430 N N   . GLN C 3 140 ? 397.986 331.948 470.356 1.00 44.41  ? 140 GLN A N   1 
ATOM 2431 C CA  . GLN C 3 140 ? 396.733 331.409 469.852 1.00 44.41  ? 140 GLN A CA  1 
ATOM 2432 C C   . GLN C 3 140 ? 395.615 332.388 470.150 1.00 44.41  ? 140 GLN A C   1 
ATOM 2433 O O   . GLN C 3 140 ? 395.492 332.859 471.281 1.00 44.41  ? 140 GLN A O   1 
ATOM 2434 C CB  . GLN C 3 140 ? 396.409 330.061 470.480 1.00 44.41  ? 140 GLN A CB  1 
ATOM 2435 C CG  . GLN C 3 140 ? 395.203 329.415 469.854 1.00 44.41  ? 140 GLN A CG  1 
ATOM 2436 C CD  . GLN C 3 140 ? 394.625 328.322 470.691 1.00 44.41  ? 140 GLN A CD  1 
ATOM 2437 O OE1 . GLN C 3 140 ? 395.019 328.127 471.836 1.00 44.41  ? 140 GLN A OE1 1 
ATOM 2438 N NE2 . GLN C 3 140 ? 393.679 327.593 470.127 1.00 44.41  ? 140 GLN A NE2 1 
ATOM 2439 N N   . ILE C 3 141 ? 394.799 332.685 469.147 1.00 42.49  ? 141 ILE A N   1 
ATOM 2440 C CA  . ILE C 3 141 ? 393.702 333.637 469.270 1.00 42.49  ? 141 ILE A CA  1 
ATOM 2441 C C   . ILE C 3 141 ? 392.421 332.883 468.946 1.00 42.49  ? 141 ILE A C   1 
ATOM 2442 O O   . ILE C 3 141 ? 392.087 332.689 467.774 1.00 42.49  ? 141 ILE A O   1 
ATOM 2443 C CB  . ILE C 3 141 ? 393.888 334.844 468.350 1.00 42.49  ? 141 ILE A CB  1 
ATOM 2444 C CG1 . ILE C 3 141 ? 395.212 335.528 468.661 1.00 42.49  ? 141 ILE A CG1 1 
ATOM 2445 C CG2 . ILE C 3 141 ? 392.764 335.819 468.536 1.00 42.49  ? 141 ILE A CG2 1 
ATOM 2446 C CD1 . ILE C 3 141 ? 395.927 336.038 467.461 1.00 42.49  ? 141 ILE A CD1 1 
ATOM 2447 N N   . MET C 3 142 ? 391.698 332.453 469.973 1.00 45.21  ? 142 MET A N   1 
ATOM 2448 C CA  . MET C 3 142 ? 390.514 331.630 469.779 1.00 45.21  ? 142 MET A CA  1 
ATOM 2449 C C   . MET C 3 142 ? 389.265 332.489 469.722 1.00 45.21  ? 142 MET A C   1 
ATOM 2450 O O   . MET C 3 142 ? 389.057 333.357 470.569 1.00 45.21  ? 142 MET A O   1 
ATOM 2451 C CB  . MET C 3 142 ? 390.374 330.607 470.902 1.00 45.21  ? 142 MET A CB  1 
ATOM 2452 C CG  . MET C 3 142 ? 389.367 329.535 470.602 1.00 45.21  ? 142 MET A CG  1 
ATOM 2453 S SD  . MET C 3 142 ? 389.014 328.474 471.998 1.00 45.21  ? 142 MET A SD  1 
ATOM 2454 C CE  . MET C 3 142 ? 388.675 329.703 473.240 1.00 45.21  ? 142 MET A CE  1 
ATOM 2455 N N   . TYR C 3 143 ? 388.429 332.236 468.723 1.00 44.72  ? 143 TYR A N   1 
ATOM 2456 C CA  . TYR C 3 143 ? 387.156 332.923 468.572 1.00 44.72  ? 143 TYR A CA  1 
ATOM 2457 C C   . TYR C 3 143 ? 386.051 331.970 468.985 1.00 44.72  ? 143 TYR A C   1 
ATOM 2458 O O   . TYR C 3 143 ? 385.964 330.858 468.461 1.00 44.72  ? 143 TYR A O   1 
ATOM 2459 C CB  . TYR C 3 143 ? 386.940 333.389 467.136 1.00 44.72  ? 143 TYR A CB  1 
ATOM 2460 C CG  . TYR C 3 143 ? 385.562 333.944 466.890 1.00 44.72  ? 143 TYR A CG  1 
ATOM 2461 C CD1 . TYR C 3 143 ? 385.168 335.134 467.466 1.00 44.72  ? 143 TYR A CD1 1 
ATOM 2462 C CD2 . TYR C 3 143 ? 384.660 333.279 466.083 1.00 44.72  ? 143 TYR A CD2 1 
ATOM 2463 C CE1 . TYR C 3 143 ? 383.915 335.644 467.250 1.00 44.72  ? 143 TYR A CE1 1 
ATOM 2464 C CE2 . TYR C 3 143 ? 383.404 333.784 465.860 1.00 44.72  ? 143 TYR A CE2 1 
ATOM 2465 C CZ  . TYR C 3 143 ? 383.039 334.965 466.449 1.00 44.72  ? 143 TYR A CZ  1 
ATOM 2466 O OH  . TYR C 3 143 ? 381.787 335.479 466.239 1.00 44.72  ? 143 TYR A OH  1 
ATOM 2467 N N   . VAL C 3 144 ? 385.213 332.400 469.917 1.00 44.96  ? 144 VAL A N   1 
ATOM 2468 C CA  . VAL C 3 144 ? 384.100 331.598 470.412 1.00 44.96  ? 144 VAL A CA  1 
ATOM 2469 C C   . VAL C 3 144 ? 382.817 332.154 469.809 1.00 44.96  ? 144 VAL A C   1 
ATOM 2470 O O   . VAL C 3 144 ? 382.441 333.287 470.136 1.00 44.96  ? 144 VAL A O   1 
ATOM 2471 C CB  . VAL C 3 144 ? 384.031 331.622 471.941 1.00 44.96  ? 144 VAL A CB  1 
ATOM 2472 C CG1 . VAL C 3 144 ? 382.839 330.847 472.409 1.00 44.96  ? 144 VAL A CG1 1 
ATOM 2473 C CG2 . VAL C 3 144 ? 385.272 331.043 472.519 1.00 44.96  ? 144 VAL A CG2 1 
ATOM 2474 N N   . PRO C 3 145 ? 382.135 331.418 468.938 1.00 45.40  ? 145 PRO A N   1 
ATOM 2475 C CA  . PRO C 3 145 ? 380.861 331.881 468.397 1.00 45.40  ? 145 PRO A CA  1 
ATOM 2476 C C   . PRO C 3 145 ? 379.808 331.959 469.485 1.00 45.40  ? 145 PRO A C   1 
ATOM 2477 O O   . PRO C 3 145 ? 379.946 331.296 470.523 1.00 45.40  ? 145 PRO A O   1 
ATOM 2478 C CB  . PRO C 3 145 ? 380.517 330.802 467.362 1.00 45.40  ? 145 PRO A CB  1 
ATOM 2479 C CG  . PRO C 3 145 ? 381.807 330.264 466.970 1.00 45.40  ? 145 PRO A CG  1 
ATOM 2480 C CD  . PRO C 3 145 ? 382.620 330.239 468.217 1.00 45.40  ? 145 PRO A CD  1 
ATOM 2481 N N   . PRO C 3 146 ? 378.761 332.785 469.306 1.00 47.05  ? 146 PRO A N   1 
ATOM 2482 C CA  . PRO C 3 146 ? 377.777 332.970 470.379 1.00 47.05  ? 146 PRO A CA  1 
ATOM 2483 C C   . PRO C 3 146 ? 376.972 331.717 470.666 1.00 47.05  ? 146 PRO A C   1 
ATOM 2484 O O   . PRO C 3 146 ? 376.205 331.245 469.824 1.00 47.05  ? 146 PRO A O   1 
ATOM 2485 C CB  . PRO C 3 146 ? 376.890 334.098 469.846 1.00 47.05  ? 146 PRO A CB  1 
ATOM 2486 C CG  . PRO C 3 146 ? 377.095 334.084 468.387 1.00 47.05  ? 146 PRO A CG  1 
ATOM 2487 C CD  . PRO C 3 146 ? 378.507 333.699 468.183 1.00 47.05  ? 146 PRO A CD  1 
ATOM 2488 N N   . GLY C 3 147 ? 377.157 331.175 471.864 1.00 52.90  ? 147 GLY A N   1 
ATOM 2489 C CA  . GLY C 3 147 ? 376.600 329.889 472.217 1.00 52.90  ? 147 GLY A CA  1 
ATOM 2490 C C   . GLY C 3 147 ? 377.629 328.785 472.110 1.00 52.90  ? 147 GLY A C   1 
ATOM 2491 O O   . GLY C 3 147 ? 377.353 327.724 471.547 1.00 52.90  ? 147 GLY A O   1 
ATOM 2492 N N   . GLY C 3 148 ? 378.823 329.026 472.641 1.00 55.32  ? 148 GLY A N   1 
ATOM 2493 C CA  . GLY C 3 148 ? 379.885 328.053 472.603 1.00 55.32  ? 148 GLY A CA  1 
ATOM 2494 C C   . GLY C 3 148 ? 380.529 327.868 473.959 1.00 55.32  ? 148 GLY A C   1 
ATOM 2495 O O   . GLY C 3 148 ? 380.231 328.594 474.910 1.00 55.32  ? 148 GLY A O   1 
ATOM 2496 N N   . PRO C 3 149 ? 381.400 326.871 474.086 1.00 53.02  ? 149 PRO A N   1 
ATOM 2497 C CA  . PRO C 3 149 ? 382.134 326.695 475.342 1.00 53.02  ? 149 PRO A CA  1 
ATOM 2498 C C   . PRO C 3 149 ? 383.169 327.786 475.547 1.00 53.02  ? 149 PRO A C   1 
ATOM 2499 O O   . PRO C 3 149 ? 383.648 328.410 474.601 1.00 53.02  ? 149 PRO A O   1 
ATOM 2500 C CB  . PRO C 3 149 ? 382.794 325.322 475.182 1.00 53.02  ? 149 PRO A CB  1 
ATOM 2501 C CG  . PRO C 3 149 ? 382.730 325.016 473.737 1.00 53.02  ? 149 PRO A CG  1 
ATOM 2502 C CD  . PRO C 3 149 ? 381.514 325.691 473.218 1.00 53.02  ? 149 PRO A CD  1 
ATOM 2503 N N   . VAL C 3 150 ? 383.506 328.009 476.811 1.00 53.06  ? 150 VAL A N   1 
ATOM 2504 C CA  . VAL C 3 150 ? 384.301 329.153 477.249 1.00 53.06  ? 150 VAL A CA  1 
ATOM 2505 C C   . VAL C 3 150 ? 385.338 328.669 478.255 1.00 53.06  ? 150 VAL A C   1 
ATOM 2506 O O   . VAL C 3 150 ? 384.993 327.926 479.184 1.00 53.06  ? 150 VAL A O   1 
ATOM 2507 C CB  . VAL C 3 150 ? 383.389 330.242 477.838 1.00 53.06  ? 150 VAL A CB  1 
ATOM 2508 C CG1 . VAL C 3 150 ? 384.107 331.085 478.865 1.00 53.06  ? 150 VAL A CG1 1 
ATOM 2509 C CG2 . VAL C 3 150 ? 382.860 331.127 476.733 1.00 53.06  ? 150 VAL A CG2 1 
ATOM 2510 N N   . PRO C 3 151 ? 386.609 329.031 478.101 1.00 52.89  ? 151 PRO A N   1 
ATOM 2511 C CA  . PRO C 3 151 ? 387.626 328.562 479.042 1.00 52.89  ? 151 PRO A CA  1 
ATOM 2512 C C   . PRO C 3 151 ? 387.521 329.250 480.389 1.00 52.89  ? 151 PRO A C   1 
ATOM 2513 O O   . PRO C 3 151 ? 387.081 330.394 480.502 1.00 52.89  ? 151 PRO A O   1 
ATOM 2514 C CB  . PRO C 3 151 ? 388.940 328.925 478.347 1.00 52.89  ? 151 PRO A CB  1 
ATOM 2515 C CG  . PRO C 3 151 ? 388.576 329.177 476.943 1.00 52.89  ? 151 PRO A CG  1 
ATOM 2516 C CD  . PRO C 3 151 ? 387.213 329.743 476.973 1.00 52.89  ? 151 PRO A CD  1 
ATOM 2517 N N   . THR C 3 152 ? 387.932 328.521 481.426 1.00 58.88  ? 152 THR A N   1 
ATOM 2518 C CA  . THR C 3 152 ? 388.027 329.060 482.773 1.00 58.88  ? 152 THR A CA  1 
ATOM 2519 C C   . THR C 3 152 ? 389.456 329.173 483.269 1.00 58.88  ? 152 THR A C   1 
ATOM 2520 O O   . THR C 3 152 ? 389.719 329.983 484.160 1.00 58.88  ? 152 THR A O   1 
ATOM 2521 C CB  . THR C 3 152 ? 387.240 328.188 483.759 1.00 58.88  ? 152 THR A CB  1 
ATOM 2522 O OG1 . THR C 3 152 ? 387.990 327.002 484.045 1.00 58.88  ? 152 THR A OG1 1 
ATOM 2523 C CG2 . THR C 3 152 ? 385.896 327.794 483.178 1.00 58.88  ? 152 THR A CG2 1 
ATOM 2524 N N   . LYS C 3 153 ? 390.370 328.373 482.736 1.00 59.79  ? 153 LYS A N   1 
ATOM 2525 C CA  . LYS C 3 153 ? 391.792 328.459 483.015 1.00 59.79  ? 153 LYS A CA  1 
ATOM 2526 C C   . LYS C 3 153 ? 392.544 328.545 481.697 1.00 59.79  ? 153 LYS A C   1 
ATOM 2527 O O   . LYS C 3 153 ? 391.949 328.562 480.621 1.00 59.79  ? 153 LYS A O   1 
ATOM 2528 C CB  . LYS C 3 153 ? 392.281 327.249 483.818 1.00 59.79  ? 153 LYS A CB  1 
ATOM 2529 C CG  . LYS C 3 153 ? 391.512 326.986 485.094 1.00 59.79  ? 153 LYS A CG  1 
ATOM 2530 C CD  . LYS C 3 153 ? 391.527 325.514 485.439 1.00 59.79  ? 153 LYS A CD  1 
ATOM 2531 C CE  . LYS C 3 153 ? 390.828 324.708 484.364 1.00 59.79  ? 153 LYS A CE  1 
ATOM 2532 N NZ  . LYS C 3 153 ? 391.194 323.269 484.432 1.00 59.79  ? 153 LYS A NZ  1 
ATOM 2533 N N   . VAL C 3 154 ? 393.872 328.593 481.783 1.00 59.48  ? 154 VAL A N   1 
ATOM 2534 C CA  . VAL C 3 154 ? 394.661 328.571 480.558 1.00 59.48  ? 154 VAL A CA  1 
ATOM 2535 C C   . VAL C 3 154 ? 394.692 327.170 479.958 1.00 59.48  ? 154 VAL A C   1 
ATOM 2536 O O   . VAL C 3 154 ? 394.504 327.008 478.747 1.00 59.48  ? 154 VAL A O   1 
ATOM 2537 C CB  . VAL C 3 154 ? 396.066 329.157 480.813 1.00 59.48  ? 154 VAL A CB  1 
ATOM 2538 C CG1 . VAL C 3 154 ? 396.744 328.509 481.998 1.00 59.48  ? 154 VAL A CG1 1 
ATOM 2539 C CG2 . VAL C 3 154 ? 396.933 329.016 479.582 1.00 59.48  ? 154 VAL A CG2 1 
ATOM 2540 N N   . LYS C 3 155 ? 394.856 326.135 480.781 1.00 63.18  ? 155 LYS A N   1 
ATOM 2541 C CA  . LYS C 3 155 ? 394.880 324.750 480.329 1.00 63.18  ? 155 LYS A CA  1 
ATOM 2542 C C   . LYS C 3 155 ? 393.480 324.185 480.519 1.00 63.18  ? 155 LYS A C   1 
ATOM 2543 O O   . LYS C 3 155 ? 393.042 323.966 481.651 1.00 63.18  ? 155 LYS A O   1 
ATOM 2544 C CB  . LYS C 3 155 ? 395.918 323.947 481.104 1.00 63.18  ? 155 LYS A CB  1 
ATOM 2545 C CG  . LYS C 3 155 ? 397.345 324.363 480.831 1.00 63.18  ? 155 LYS A CG  1 
ATOM 2546 C CD  . LYS C 3 155 ? 398.330 323.548 481.646 1.00 63.18  ? 155 LYS A CD  1 
ATOM 2547 C CE  . LYS C 3 155 ? 399.758 323.959 481.344 1.00 63.18  ? 155 LYS A CE  1 
ATOM 2548 N NZ  . LYS C 3 155 ? 400.747 323.191 482.148 1.00 63.18  ? 155 LYS A NZ  1 
ATOM 2549 N N   . ASP C 3 156 ? 392.779 323.951 479.414 1.00 61.03  ? 156 ASP A N   1 
ATOM 2550 C CA  . ASP C 3 156 ? 391.366 323.620 479.465 1.00 61.03  ? 156 ASP A CA  1 
ATOM 2551 C C   . ASP C 3 156 ? 390.976 322.917 478.176 1.00 61.03  ? 156 ASP A C   1 
ATOM 2552 O O   . ASP C 3 156 ? 391.616 323.080 477.139 1.00 61.03  ? 156 ASP A O   1 
ATOM 2553 C CB  . ASP C 3 156 ? 390.517 324.875 479.674 1.00 61.03  ? 156 ASP A CB  1 
ATOM 2554 C CG  . ASP C 3 156 ? 389.144 324.568 480.209 1.00 61.03  ? 156 ASP A CG  1 
ATOM 2555 O OD1 . ASP C 3 156 ? 389.029 324.270 481.413 1.00 61.03  ? 156 ASP A OD1 1 
ATOM 2556 O OD2 . ASP C 3 156 ? 388.176 324.626 479.427 1.00 61.03  ? 156 ASP A OD2 1 
ATOM 2557 N N   . TYR C 3 157 ? 389.903 322.135 478.248 1.00 61.61  ? 157 TYR A N   1 
ATOM 2558 C CA  . TYR C 3 157 ? 389.421 321.419 477.078 1.00 61.61  ? 157 TYR A CA  1 
ATOM 2559 C C   . TYR C 3 157 ? 388.639 322.306 476.129 1.00 61.61  ? 157 TYR A C   1 
ATOM 2560 O O   . TYR C 3 157 ? 388.338 321.870 475.015 1.00 61.61  ? 157 TYR A O   1 
ATOM 2561 C CB  . TYR C 3 157 ? 388.550 320.233 477.496 1.00 61.61  ? 157 TYR A CB  1 
ATOM 2562 C CG  . TYR C 3 157 ? 387.193 320.604 478.060 1.00 61.61  ? 157 TYR A CG  1 
ATOM 2563 C CD1 . TYR C 3 157 ? 387.059 321.020 479.379 1.00 61.61  ? 157 TYR A CD1 1 
ATOM 2564 C CD2 . TYR C 3 157 ? 386.042 320.518 477.281 1.00 61.61  ? 157 TYR A CD2 1 
ATOM 2565 C CE1 . TYR C 3 157 ? 385.823 321.359 479.900 1.00 61.61  ? 157 TYR A CE1 1 
ATOM 2566 C CE2 . TYR C 3 157 ? 384.803 320.856 477.794 1.00 61.61  ? 157 TYR A CE2 1 
ATOM 2567 C CZ  . TYR C 3 157 ? 384.700 321.273 479.105 1.00 61.61  ? 157 TYR A CZ  1 
ATOM 2568 O OH  . TYR C 3 157 ? 383.472 321.607 479.624 1.00 61.61  ? 157 TYR A OH  1 
ATOM 2569 N N   . ALA C 3 158 ? 388.287 323.521 476.541 1.00 54.69  ? 158 ALA A N   1 
ATOM 2570 C CA  . ALA C 3 158 ? 387.523 324.409 475.679 1.00 54.69  ? 158 ALA A CA  1 
ATOM 2571 C C   . ALA C 3 158 ? 388.383 325.106 474.646 1.00 54.69  ? 158 ALA A C   1 
ATOM 2572 O O   . ALA C 3 158 ? 387.839 325.757 473.754 1.00 54.69  ? 158 ALA A O   1 
ATOM 2573 C CB  . ALA C 3 158 ? 386.783 325.454 476.510 1.00 54.69  ? 158 ALA A CB  1 
ATOM 2574 N N   . TRP C 3 159 ? 389.704 325.010 474.758 1.00 51.39  ? 159 TRP A N   1 
ATOM 2575 C CA  . TRP C 3 159 ? 390.568 325.525 473.710 1.00 51.39  ? 159 TRP A CA  1 
ATOM 2576 C C   . TRP C 3 159 ? 390.609 324.592 472.518 1.00 51.39  ? 159 TRP A C   1 
ATOM 2577 O O   . TRP C 3 159 ? 390.675 325.052 471.376 1.00 51.39  ? 159 TRP A O   1 
ATOM 2578 C CB  . TRP C 3 159 ? 391.982 325.728 474.242 1.00 51.39  ? 159 TRP A CB  1 
ATOM 2579 C CG  . TRP C 3 159 ? 392.084 326.765 475.288 1.00 51.39  ? 159 TRP A CG  1 
ATOM 2580 C CD1 . TRP C 3 159 ? 391.983 326.584 476.625 1.00 51.39  ? 159 TRP A CD1 1 
ATOM 2581 C CD2 . TRP C 3 159 ? 392.321 328.158 475.088 1.00 51.39  ? 159 TRP A CD2 1 
ATOM 2582 N NE1 . TRP C 3 159 ? 392.139 327.776 477.278 1.00 51.39  ? 159 TRP A NE1 1 
ATOM 2583 C CE2 . TRP C 3 159 ? 392.348 328.759 476.351 1.00 51.39  ? 159 TRP A CE2 1 
ATOM 2584 C CE3 . TRP C 3 159 ? 392.514 328.954 473.960 1.00 51.39  ? 159 TRP A CE3 1 
ATOM 2585 C CZ2 . TRP C 3 159 ? 392.560 330.115 476.518 1.00 51.39  ? 159 TRP A CZ2 1 
ATOM 2586 C CZ3 . TRP C 3 159 ? 392.721 330.291 474.129 1.00 51.39  ? 159 TRP A CZ3 1 
ATOM 2587 C CH2 . TRP C 3 159 ? 392.744 330.861 475.396 1.00 51.39  ? 159 TRP A CH2 1 
ATOM 2588 N N   . GLN C 3 160 ? 390.556 323.289 472.765 1.00 55.08  ? 160 GLN A N   1 
ATOM 2589 C CA  . GLN C 3 160 ? 390.800 322.277 471.753 1.00 55.08  ? 160 GLN A CA  1 
ATOM 2590 C C   . GLN C 3 160 ? 389.549 321.899 470.977 1.00 55.08  ? 160 GLN A C   1 
ATOM 2591 O O   . GLN C 3 160 ? 389.603 320.967 470.171 1.00 55.08  ? 160 GLN A O   1 
ATOM 2592 C CB  . GLN C 3 160 ? 391.389 321.028 472.405 1.00 55.08  ? 160 GLN A CB  1 
ATOM 2593 C CG  . GLN C 3 160 ? 392.607 321.277 473.259 1.00 55.08  ? 160 GLN A CG  1 
ATOM 2594 C CD  . GLN C 3 160 ? 393.803 321.696 472.451 1.00 55.08  ? 160 GLN A CD  1 
ATOM 2595 O OE1 . GLN C 3 160 ? 394.178 322.865 472.444 1.00 55.08  ? 160 GLN A OE1 1 
ATOM 2596 N NE2 . GLN C 3 160 ? 394.421 320.742 471.765 1.00 55.08  ? 160 GLN A NE2 1 
ATOM 2597 N N   . THR C 3 161 ? 388.426 322.580 471.202 1.00 52.75  ? 161 THR A N   1 
ATOM 2598 C CA  . THR C 3 161 ? 387.203 322.184 470.524 1.00 52.75  ? 161 THR A CA  1 
ATOM 2599 C C   . THR C 3 161 ? 387.235 322.595 469.059 1.00 52.75  ? 161 THR A C   1 
ATOM 2600 O O   . THR C 3 161 ? 387.815 323.611 468.677 1.00 52.75  ? 161 THR A O   1 
ATOM 2601 C CB  . THR C 3 161 ? 385.969 322.765 471.210 1.00 52.75  ? 161 THR A CB  1 
ATOM 2602 O OG1 . THR C 3 161 ? 384.809 322.447 470.438 1.00 52.75  ? 161 THR A OG1 1 
ATOM 2603 C CG2 . THR C 3 161 ? 386.070 324.245 471.351 1.00 52.75  ? 161 THR A CG2 1 
ATOM 2604 N N   . SER C 3 162 ? 386.607 321.769 468.232 1.00 53.05  ? 162 SER A N   1 
ATOM 2605 C CA  . SER C 3 162 ? 386.769 321.865 466.790 1.00 53.05  ? 162 SER A CA  1 
ATOM 2606 C C   . SER C 3 162 ? 385.875 322.910 466.149 1.00 53.05  ? 162 SER A C   1 
ATOM 2607 O O   . SER C 3 162 ? 386.066 323.237 464.975 1.00 53.05  ? 162 SER A O   1 
ATOM 2608 C CB  . SER C 3 162 ? 386.491 320.513 466.142 1.00 53.05  ? 162 SER A CB  1 
ATOM 2609 O OG  . SER C 3 162 ? 386.137 320.688 464.786 1.00 53.05  ? 162 SER A OG  1 
ATOM 2610 N N   . THR C 3 163 ? 384.903 323.435 466.877 1.00 52.39  ? 163 THR A N   1 
ATOM 2611 C CA  . THR C 3 163 ? 383.990 324.415 466.318 1.00 52.39  ? 163 THR A CA  1 
ATOM 2612 C C   . THR C 3 163 ? 384.331 325.839 466.723 1.00 52.39  ? 163 THR A C   1 
ATOM 2613 O O   . THR C 3 163 ? 383.592 326.759 466.368 1.00 52.39  ? 163 THR A O   1 
ATOM 2614 C CB  . THR C 3 163 ? 382.562 324.089 466.735 1.00 52.39  ? 163 THR A CB  1 
ATOM 2615 O OG1 . THR C 3 163 ? 382.427 324.283 468.145 1.00 52.39  ? 163 THR A OG1 1 
ATOM 2616 C CG2 . THR C 3 163 ? 382.250 322.650 466.408 1.00 52.39  ? 163 THR A CG2 1 
ATOM 2617 N N   . ASN C 3 164 ? 385.423 326.042 467.455 1.00 48.15  ? 164 ASN A N   1 
ATOM 2618 C CA  . ASN C 3 164 ? 385.891 327.376 467.800 1.00 48.15  ? 164 ASN A CA  1 
ATOM 2619 C C   . ASN C 3 164 ? 387.109 327.665 466.943 1.00 48.15  ? 164 ASN A C   1 
ATOM 2620 O O   . ASN C 3 164 ? 388.204 327.178 467.257 1.00 48.15  ? 164 ASN A O   1 
ATOM 2621 C CB  . ASN C 3 164 ? 386.246 327.471 469.284 1.00 48.15  ? 164 ASN A CB  1 
ATOM 2622 C CG  . ASN C 3 164 ? 385.036 327.432 470.189 1.00 48.15  ? 164 ASN A CG  1 
ATOM 2623 O OD1 . ASN C 3 164 ? 385.172 327.433 471.408 1.00 48.15  ? 164 ASN A OD1 1 
ATOM 2624 N ND2 . ASN C 3 164 ? 383.850 327.394 469.605 1.00 48.15  ? 164 ASN A ND2 1 
ATOM 2625 N N   . PRO C 3 165 ? 386.985 328.424 465.853 1.00 45.17  ? 165 PRO A N   1 
ATOM 2626 C CA  . PRO C 3 165 ? 388.123 328.628 464.946 1.00 45.17  ? 165 PRO A CA  1 
ATOM 2627 C C   . PRO C 3 165 ? 389.163 329.539 465.577 1.00 45.17  ? 165 PRO A C   1 
ATOM 2628 O O   . PRO C 3 165 ? 388.826 330.547 466.196 1.00 45.17  ? 165 PRO A O   1 
ATOM 2629 C CB  . PRO C 3 165 ? 387.482 329.270 463.713 1.00 45.17  ? 165 PRO A CB  1 
ATOM 2630 C CG  . PRO C 3 165 ? 386.241 329.875 464.204 1.00 45.17  ? 165 PRO A CG  1 
ATOM 2631 C CD  . PRO C 3 165 ? 385.753 329.034 465.332 1.00 45.17  ? 165 PRO A CD  1 
ATOM 2632 N N   . SER C 3 166 ? 390.428 329.171 465.431 1.00 43.75  ? 166 SER A N   1 
ATOM 2633 C CA  . SER C 3 166 ? 391.531 329.875 466.056 1.00 43.75  ? 166 SER A CA  1 
ATOM 2634 C C   . SER C 3 166 ? 392.605 330.158 465.020 1.00 43.75  ? 166 SER A C   1 
ATOM 2635 O O   . SER C 3 166 ? 392.686 329.487 463.990 1.00 43.75  ? 166 SER A O   1 
ATOM 2636 C CB  . SER C 3 166 ? 392.131 329.048 467.191 1.00 43.75  ? 166 SER A CB  1 
ATOM 2637 O OG  . SER C 3 166 ? 391.121 328.380 467.920 1.00 43.75  ? 166 SER A OG  1 
ATOM 2638 N N   . VAL C 3 167 ? 393.439 331.154 465.297 1.00 40.56  ? 167 VAL A N   1 
ATOM 2639 C CA  . VAL C 3 167 ? 394.599 331.419 464.459 1.00 40.56  ? 167 VAL A CA  1 
ATOM 2640 C C   . VAL C 3 167 ? 395.845 331.284 465.316 1.00 40.56  ? 167 VAL A C   1 
ATOM 2641 O O   . VAL C 3 167 ? 395.829 331.537 466.524 1.00 40.56  ? 167 VAL A O   1 
ATOM 2642 C CB  . VAL C 3 167 ? 394.555 332.799 463.748 1.00 40.56  ? 167 VAL A CB  1 
ATOM 2643 C CG1 . VAL C 3 167 ? 393.307 332.940 462.922 1.00 40.56  ? 167 VAL A CG1 1 
ATOM 2644 C CG2 . VAL C 3 167 ? 394.624 333.933 464.716 1.00 40.56  ? 167 VAL A CG2 1 
ATOM 2645 N N   . PHE C 3 168 ? 396.919 330.828 464.687 1.00 41.05  ? 168 PHE A N   1 
ATOM 2646 C CA  . PHE C 3 168 ? 398.222 330.711 465.319 1.00 41.05  ? 168 PHE A CA  1 
ATOM 2647 C C   . PHE C 3 168 ? 399.175 331.627 464.574 1.00 41.05  ? 168 PHE A C   1 
ATOM 2648 O O   . PHE C 3 168 ? 399.037 331.810 463.362 1.00 41.05  ? 168 PHE A O   1 
ATOM 2649 C CB  . PHE C 3 168 ? 398.737 329.271 465.289 1.00 41.05  ? 168 PHE A CB  1 
ATOM 2650 C CG  . PHE C 3 168 ? 397.940 328.319 466.128 1.00 41.05  ? 168 PHE A CG  1 
ATOM 2651 C CD1 . PHE C 3 168 ? 396.831 327.679 465.610 1.00 41.05  ? 168 PHE A CD1 1 
ATOM 2652 C CD2 . PHE C 3 168 ? 398.310 328.050 467.426 1.00 41.05  ? 168 PHE A CD2 1 
ATOM 2653 C CE1 . PHE C 3 168 ? 396.104 326.807 466.375 1.00 41.05  ? 168 PHE A CE1 1 
ATOM 2654 C CE2 . PHE C 3 168 ? 397.585 327.175 468.193 1.00 41.05  ? 168 PHE A CE2 1 
ATOM 2655 C CZ  . PHE C 3 168 ? 396.483 326.554 467.664 1.00 41.05  ? 168 PHE A CZ  1 
ATOM 2656 N N   . TRP C 3 169 ? 400.140 332.195 465.289 1.00 42.74  ? 169 TRP A N   1 
ATOM 2657 C CA  . TRP C 3 169 ? 401.007 333.211 464.721 1.00 42.74  ? 169 TRP A CA  1 
ATOM 2658 C C   . TRP C 3 169 ? 402.279 333.304 465.544 1.00 42.74  ? 169 TRP A C   1 
ATOM 2659 O O   . TRP C 3 169 ? 402.216 333.340 466.773 1.00 42.74  ? 169 TRP A O   1 
ATOM 2660 C CB  . TRP C 3 169 ? 400.284 334.553 464.692 1.00 42.74  ? 169 TRP A CB  1 
ATOM 2661 C CG  . TRP C 3 169 ? 401.113 335.689 464.270 1.00 42.74  ? 169 TRP A CG  1 
ATOM 2662 C CD1 . TRP C 3 169 ? 401.420 336.049 463.000 1.00 42.74  ? 169 TRP A CD1 1 
ATOM 2663 C CD2 . TRP C 3 169 ? 401.731 336.648 465.121 1.00 42.74  ? 169 TRP A CD2 1 
ATOM 2664 N NE1 . TRP C 3 169 ? 402.202 337.169 463.004 1.00 42.74  ? 169 TRP A NE1 1 
ATOM 2665 C CE2 . TRP C 3 169 ? 402.405 337.558 464.300 1.00 42.74  ? 169 TRP A CE2 1 
ATOM 2666 C CE3 . TRP C 3 169 ? 401.783 336.821 466.503 1.00 42.74  ? 169 TRP A CE3 1 
ATOM 2667 C CZ2 . TRP C 3 169 ? 403.126 338.620 464.809 1.00 42.74  ? 169 TRP A CZ2 1 
ATOM 2668 C CZ3 . TRP C 3 169 ? 402.497 337.873 467.006 1.00 42.74  ? 169 TRP A CZ3 1 
ATOM 2669 C CH2 . TRP C 3 169 ? 403.158 338.762 466.164 1.00 42.74  ? 169 TRP A CH2 1 
ATOM 2670 N N   . THR C 3 170 ? 403.424 333.332 464.872 1.00 46.20  ? 170 THR A N   1 
ATOM 2671 C CA  . THR C 3 170 ? 404.711 333.478 465.535 1.00 46.20  ? 170 THR A CA  1 
ATOM 2672 C C   . THR C 3 170 ? 405.210 334.910 465.425 1.00 46.20  ? 170 THR A C   1 
ATOM 2673 O O   . THR C 3 170 ? 404.826 335.648 464.519 1.00 46.20  ? 170 THR A O   1 
ATOM 2674 C CB  . THR C 3 170 ? 405.744 332.548 464.922 1.00 46.20  ? 170 THR A CB  1 
ATOM 2675 O OG1 . THR C 3 170 ? 406.177 333.104 463.681 1.00 46.20  ? 170 THR A OG1 1 
ATOM 2676 C CG2 . THR C 3 170 ? 405.142 331.197 464.665 1.00 46.20  ? 170 THR A CG2 1 
ATOM 2677 N N   . GLU C 3 171 ? 406.091 335.290 466.343 1.00 50.71  ? 171 GLU A N   1 
ATOM 2678 C CA  . GLU C 3 171 ? 406.597 336.654 466.378 1.00 50.71  ? 171 GLU A CA  1 
ATOM 2679 C C   . GLU C 3 171 ? 407.528 336.932 465.207 1.00 50.71  ? 171 GLU A C   1 
ATOM 2680 O O   . GLU C 3 171 ? 408.385 336.119 464.856 1.00 50.71  ? 171 GLU A O   1 
ATOM 2681 C CB  . GLU C 3 171 ? 407.342 336.911 467.682 1.00 50.71  ? 171 GLU A CB  1 
ATOM 2682 C CG  . GLU C 3 171 ? 406.457 336.942 468.904 1.00 50.71  ? 171 GLU A CG  1 
ATOM 2683 C CD  . GLU C 3 171 ? 407.246 337.094 470.189 1.00 50.71  ? 171 GLU A CD  1 
ATOM 2684 O OE1 . GLU C 3 171 ? 406.649 337.496 471.207 1.00 50.71  ? 171 GLU A OE1 1 
ATOM 2685 O OE2 . GLU C 3 171 ? 408.462 336.815 470.181 1.00 50.71  ? 171 GLU A OE2 1 
ATOM 2686 N N   . GLY C 3 172 ? 407.358 338.100 464.603 1.00 46.91  ? 172 GLY A N   1 
ATOM 2687 C CA  . GLY C 3 172 ? 408.225 338.540 463.535 1.00 46.91  ? 172 GLY A CA  1 
ATOM 2688 C C   . GLY C 3 172 ? 407.626 338.525 462.151 1.00 46.91  ? 172 GLY A C   1 
ATOM 2689 O O   . GLY C 3 172 ? 408.379 338.579 461.174 1.00 46.91  ? 172 GLY A O   1 
ATOM 2690 N N   . ASN C 3 173 ? 406.309 338.463 462.030 1.00 45.24  ? 173 ASN A N   1 
ATOM 2691 C CA  . ASN C 3 173 ? 405.642 338.405 460.741 1.00 45.24  ? 173 ASN A CA  1 
ATOM 2692 C C   . ASN C 3 173 ? 404.599 339.518 460.659 1.00 45.24  ? 173 ASN A C   1 
ATOM 2693 O O   . ASN C 3 173 ? 404.558 340.420 461.495 1.00 45.24  ? 173 ASN A O   1 
ATOM 2694 C CB  . ASN C 3 173 ? 405.011 337.030 460.537 1.00 45.24  ? 173 ASN A CB  1 
ATOM 2695 C CG  . ASN C 3 173 ? 406.002 335.908 460.710 1.00 45.24  ? 173 ASN A CG  1 
ATOM 2696 O OD1 . ASN C 3 173 ? 407.155 336.022 460.317 1.00 45.24  ? 173 ASN A OD1 1 
ATOM 2697 N ND2 . ASN C 3 173 ? 405.555 334.811 461.301 1.00 45.24  ? 173 ASN A ND2 1 
ATOM 2698 N N   . ALA C 3 174 ? 403.765 339.457 459.629 1.00 42.24  ? 174 ALA A N   1 
ATOM 2699 C CA  . ALA C 3 174 ? 402.640 340.366 459.532 1.00 42.24  ? 174 ALA A CA  1 
ATOM 2700 C C   . ALA C 3 174 ? 401.599 340.001 460.588 1.00 42.24  ? 174 ALA A C   1 
ATOM 2701 O O   . ALA C 3 174 ? 401.491 338.837 460.976 1.00 42.24  ? 174 ALA A O   1 
ATOM 2702 C CB  . ALA C 3 174 ? 402.028 340.304 458.137 1.00 42.24  ? 174 ALA A CB  1 
ATOM 2703 N N   . PRO C 3 175 ? 400.845 340.981 461.095 1.00 40.67  ? 175 PRO A N   1 
ATOM 2704 C CA  . PRO C 3 175 ? 399.910 340.693 462.179 1.00 40.67  ? 175 PRO A CA  1 
ATOM 2705 C C   . PRO C 3 175 ? 398.727 339.874 461.694 1.00 40.67  ? 175 PRO A C   1 
ATOM 2706 O O   . PRO C 3 175 ? 398.350 339.939 460.512 1.00 40.67  ? 175 PRO A O   1 
ATOM 2707 C CB  . PRO C 3 175 ? 399.475 342.092 462.649 1.00 40.67  ? 175 PRO A CB  1 
ATOM 2708 C CG  . PRO C 3 175 ? 399.794 342.980 461.529 1.00 40.67  ? 175 PRO A CG  1 
ATOM 2709 C CD  . PRO C 3 175 ? 401.020 342.429 460.916 1.00 40.67  ? 175 PRO A CD  1 
ATOM 2710 N N   . PRO C 3 176 ? 398.115 339.072 462.571 1.00 38.23  ? 176 PRO A N   1 
ATOM 2711 C CA  . PRO C 3 176 ? 397.110 338.099 462.128 1.00 38.23  ? 176 PRO A CA  1 
ATOM 2712 C C   . PRO C 3 176 ? 395.696 338.625 461.921 1.00 38.23  ? 176 PRO A C   1 
ATOM 2713 O O   . PRO C 3 176 ? 394.892 338.625 462.851 1.00 38.23  ? 176 PRO A O   1 
ATOM 2714 C CB  . PRO C 3 176 ? 397.145 337.052 463.243 1.00 38.23  ? 176 PRO A CB  1 
ATOM 2715 C CG  . PRO C 3 176 ? 397.599 337.766 464.414 1.00 38.23  ? 176 PRO A CG  1 
ATOM 2716 C CD  . PRO C 3 176 ? 398.520 338.832 463.963 1.00 38.23  ? 176 PRO A CD  1 
ATOM 2717 N N   . ARG C 3 177 ? 395.373 339.087 460.723 1.00 42.35  ? 177 ARG A N   1 
ATOM 2718 C CA  . ARG C 3 177 ? 394.000 339.463 460.413 1.00 42.35  ? 177 ARG A CA  1 
ATOM 2719 C C   . ARG C 3 177 ? 393.086 338.243 460.325 1.00 42.35  ? 177 ARG A C   1 
ATOM 2720 O O   . ARG C 3 177 ? 393.511 337.145 459.966 1.00 42.35  ? 177 ARG A O   1 
ATOM 2721 C CB  . ARG C 3 177 ? 393.956 340.225 459.094 1.00 42.35  ? 177 ARG A CB  1 
ATOM 2722 C CG  . ARG C 3 177 ? 392.813 341.179 458.955 1.00 42.35  ? 177 ARG A CG  1 
ATOM 2723 C CD  . ARG C 3 177 ? 392.819 341.797 457.593 1.00 42.35  ? 177 ARG A CD  1 
ATOM 2724 N NE  . ARG C 3 177 ? 393.946 342.694 457.408 1.00 42.35  ? 177 ARG A NE  1 
ATOM 2725 C CZ  . ARG C 3 177 ? 393.834 344.005 457.251 1.00 42.35  ? 177 ARG A CZ  1 
ATOM 2726 N NH1 . ARG C 3 177 ? 392.643 344.573 457.251 1.00 42.35  ? 177 ARG A NH1 1 
ATOM 2727 N NH2 . ARG C 3 177 ? 394.912 344.750 457.082 1.00 42.35  ? 177 ARG A NH2 1 
ATOM 2728 N N   . MET C 3 178 ? 391.814 338.451 460.668 1.00 49.43  ? 178 MET A N   1 
ATOM 2729 C CA  . MET C 3 178 ? 390.737 337.495 460.437 1.00 49.43  ? 178 MET A CA  1 
ATOM 2730 C C   . MET C 3 178 ? 389.436 338.275 460.314 1.00 49.43  ? 178 MET A C   1 
ATOM 2731 O O   . MET C 3 178 ? 389.308 339.381 460.841 1.00 49.43  ? 178 MET A O   1 
ATOM 2732 C CB  . MET C 3 178 ? 390.636 336.454 461.555 1.00 49.43  ? 178 MET A CB  1 
ATOM 2733 C CG  . MET C 3 178 ? 390.181 337.011 462.895 1.00 49.43  ? 178 MET A CG  1 
ATOM 2734 S SD  . MET C 3 178 ? 390.505 335.928 464.301 1.00 49.43  ? 178 MET A SD  1 
ATOM 2735 C CE  . MET C 3 178 ? 389.069 334.870 464.271 1.00 49.43  ? 178 MET A CE  1 
ATOM 2736 N N   . SER C 3 179 ? 388.472 337.705 459.604 1.00 50.35  ? 179 SER A N   1 
ATOM 2737 C CA  . SER C 3 179 ? 387.253 338.422 459.257 1.00 50.35  ? 179 SER A CA  1 
ATOM 2738 C C   . SER C 3 179 ? 386.027 337.590 459.590 1.00 50.35  ? 179 SER A C   1 
ATOM 2739 O O   . SER C 3 179 ? 385.995 336.389 459.323 1.00 50.35  ? 179 SER A O   1 
ATOM 2740 C CB  . SER C 3 179 ? 387.237 338.780 457.779 1.00 50.35  ? 179 SER A CB  1 
ATOM 2741 O OG  . SER C 3 179 ? 385.917 339.007 457.331 1.00 50.35  ? 179 SER A OG  1 
ATOM 2742 N N   . ILE C 3 180 ? 385.011 338.235 460.154 1.00 47.01  ? 180 ILE A N   1 
ATOM 2743 C CA  . ILE C 3 180 ? 383.803 337.570 460.626 1.00 47.01  ? 180 ILE A CA  1 
ATOM 2744 C C   . ILE C 3 180 ? 382.615 338.177 459.891 1.00 47.01  ? 180 ILE A C   1 
ATOM 2745 O O   . ILE C 3 180 ? 382.452 339.396 459.909 1.00 47.01  ? 180 ILE A O   1 
ATOM 2746 C CB  . ILE C 3 180 ? 383.616 337.718 462.146 1.00 47.01  ? 180 ILE A CB  1 
ATOM 2747 C CG1 . ILE C 3 180 ? 384.859 337.241 462.881 1.00 47.01  ? 180 ILE A CG1 1 
ATOM 2748 C CG2 . ILE C 3 180 ? 382.418 336.947 462.619 1.00 47.01  ? 180 ILE A CG2 1 
ATOM 2749 C CD1 . ILE C 3 180 ? 384.923 337.712 464.298 1.00 47.01  ? 180 ILE A CD1 1 
ATOM 2750 N N   . PRO C 3 181 ? 381.756 337.383 459.262 1.00 47.25  ? 181 PRO A N   1 
ATOM 2751 C CA  . PRO C 3 181 ? 380.602 337.928 458.540 1.00 47.25  ? 181 PRO A CA  1 
ATOM 2752 C C   . PRO C 3 181 ? 379.506 338.382 459.498 1.00 47.25  ? 181 PRO A C   1 
ATOM 2753 O O   . PRO C 3 181 ? 379.684 338.435 460.709 1.00 47.25  ? 181 PRO A O   1 
ATOM 2754 C CB  . PRO C 3 181 ? 380.140 336.747 457.696 1.00 47.25  ? 181 PRO A CB  1 
ATOM 2755 C CG  . PRO C 3 181 ? 380.515 335.576 458.503 1.00 47.25  ? 181 PRO A CG  1 
ATOM 2756 C CD  . PRO C 3 181 ? 381.833 335.922 459.123 1.00 47.25  ? 181 PRO A CD  1 
ATOM 2757 N N   . PHE C 3 182 ? 378.357 338.728 458.927 1.00 48.63  ? 182 PHE A N   1 
ATOM 2758 C CA  . PHE C 3 182 ? 377.218 339.176 459.724 1.00 48.63  ? 182 PHE A CA  1 
ATOM 2759 C C   . PHE C 3 182 ? 376.622 337.972 460.430 1.00 48.63  ? 182 PHE A C   1 
ATOM 2760 O O   . PHE C 3 182 ? 375.851 337.212 459.845 1.00 48.63  ? 182 PHE A O   1 
ATOM 2761 C CB  . PHE C 3 182 ? 376.169 339.860 458.861 1.00 48.63  ? 182 PHE A CB  1 
ATOM 2762 C CG  . PHE C 3 182 ? 374.922 340.208 459.609 1.00 48.63  ? 182 PHE A CG  1 
ATOM 2763 C CD1 . PHE C 3 182 ? 374.943 341.174 460.587 1.00 48.63  ? 182 PHE A CD1 1 
ATOM 2764 C CD2 . PHE C 3 182 ? 373.736 339.562 459.351 1.00 48.63  ? 182 PHE A CD2 1 
ATOM 2765 C CE1 . PHE C 3 182 ? 373.808 341.491 461.287 1.00 48.63  ? 182 PHE A CE1 1 
ATOM 2766 C CE2 . PHE C 3 182 ? 372.599 339.881 460.052 1.00 48.63  ? 182 PHE A CE2 1 
ATOM 2767 C CZ  . PHE C 3 182 ? 372.640 340.844 461.020 1.00 48.63  ? 182 PHE A CZ  1 
ATOM 2768 N N   . ILE C 3 183 ? 376.971 337.794 461.695 1.00 50.76  ? 183 ILE A N   1 
ATOM 2769 C CA  . ILE C 3 183 ? 376.514 336.650 462.466 1.00 50.76  ? 183 ILE A CA  1 
ATOM 2770 C C   . ILE C 3 183 ? 375.454 337.120 463.454 1.00 50.76  ? 183 ILE A C   1 
ATOM 2771 O O   . ILE C 3 183 ? 375.753 337.780 464.454 1.00 50.76  ? 183 ILE A O   1 
ATOM 2772 C CB  . ILE C 3 183 ? 377.685 335.920 463.138 1.00 50.76  ? 183 ILE A CB  1 
ATOM 2773 C CG1 . ILE C 3 183 ? 377.178 334.817 464.063 1.00 50.76  ? 183 ILE A CG1 1 
ATOM 2774 C CG2 . ILE C 3 183 ? 378.713 336.871 463.760 1.00 50.76  ? 183 ILE A CG2 1 
ATOM 2775 C CD1 . ILE C 3 183 ? 378.248 333.843 464.465 1.00 50.76  ? 183 ILE A CD1 1 
ATOM 2776 N N   . SER C 3 184 ? 374.201 336.793 463.145 1.00 51.39  ? 184 SER A N   1 
ATOM 2777 C CA  . SER C 3 184 ? 373.028 337.112 463.947 1.00 51.39  ? 184 SER A CA  1 
ATOM 2778 C C   . SER C 3 184 ? 371.857 336.320 463.403 1.00 51.39  ? 184 SER A C   1 
ATOM 2779 O O   . SER C 3 184 ? 371.837 335.959 462.225 1.00 51.39  ? 184 SER A O   1 
ATOM 2780 C CB  . SER C 3 184 ? 372.696 338.606 463.916 1.00 51.39  ? 184 SER A CB  1 
ATOM 2781 O OG  . SER C 3 184 ? 371.831 338.944 464.981 1.00 51.39  ? 184 SER A OG  1 
ATOM 2782 N N   . ILE C 3 185 ? 370.879 336.060 464.266 1.00 49.85  ? 185 ILE A N   1 
ATOM 2783 C CA  . ILE C 3 185 ? 369.672 335.380 463.816 1.00 49.85  ? 185 ILE A CA  1 
ATOM 2784 C C   . ILE C 3 185 ? 368.699 336.375 463.195 1.00 49.85  ? 185 ILE A C   1 
ATOM 2785 O O   . ILE C 3 185 ? 367.941 336.034 462.283 1.00 49.85  ? 185 ILE A O   1 
ATOM 2786 C CB  . ILE C 3 185 ? 369.040 334.607 464.983 1.00 49.85  ? 185 ILE A CB  1 
ATOM 2787 C CG1 . ILE C 3 185 ? 370.120 333.859 465.755 1.00 49.85  ? 185 ILE A CG1 1 
ATOM 2788 C CG2 . ILE C 3 185 ? 367.996 333.628 464.480 1.00 49.85  ? 185 ILE A CG2 1 
ATOM 2789 C CD1 . ILE C 3 185 ? 370.695 332.669 465.011 1.00 49.85  ? 185 ILE A CD1 1 
ATOM 2790 N N   . GLY C 3 186 ? 368.724 337.623 463.645 1.00 50.60  ? 186 GLY A N   1 
ATOM 2791 C CA  . GLY C 3 186 ? 367.896 338.661 463.074 1.00 50.60  ? 186 GLY A CA  1 
ATOM 2792 C C   . GLY C 3 186 ? 368.413 339.141 461.733 1.00 50.60  ? 186 GLY A C   1 
ATOM 2793 O O   . GLY C 3 186 ? 369.178 338.469 461.041 1.00 50.60  ? 186 GLY A O   1 
ATOM 2794 N N   . ASN C 3 187 ? 367.975 340.335 461.357 1.00 49.67  ? 187 ASN A N   1 
ATOM 2795 C CA  . ASN C 3 187 ? 368.388 340.922 460.093 1.00 49.67  ? 187 ASN A CA  1 
ATOM 2796 C C   . ASN C 3 187 ? 369.214 342.185 460.260 1.00 49.67  ? 187 ASN A C   1 
ATOM 2797 O O   . ASN C 3 187 ? 369.678 342.734 459.257 1.00 49.67  ? 187 ASN A O   1 
ATOM 2798 C CB  . ASN C 3 187 ? 367.169 341.218 459.231 1.00 49.67  ? 187 ASN A CB  1 
ATOM 2799 C CG  . ASN C 3 187 ? 366.330 340.000 458.995 1.00 49.67  ? 187 ASN A CG  1 
ATOM 2800 O OD1 . ASN C 3 187 ? 365.624 339.543 459.884 1.00 49.67  ? 187 ASN A OD1 1 
ATOM 2801 N ND2 . ASN C 3 187 ? 366.404 339.456 457.794 1.00 49.67  ? 187 ASN A ND2 1 
ATOM 2802 N N   . ALA C 3 188 ? 369.416 342.648 461.491 1.00 46.40  ? 188 ALA A N   1 
ATOM 2803 C CA  . ALA C 3 188 ? 370.192 343.848 461.751 1.00 46.40  ? 188 ALA A CA  1 
ATOM 2804 C C   . ALA C 3 188 ? 370.613 343.858 463.208 1.00 46.40  ? 188 ALA A C   1 
ATOM 2805 O O   . ALA C 3 188 ? 369.889 343.383 464.081 1.00 46.40  ? 188 ALA A O   1 
ATOM 2806 C CB  . ALA C 3 188 ? 369.397 345.109 461.431 1.00 46.40  ? 188 ALA A CB  1 
ATOM 2807 N N   . TYR C 3 189 ? 371.796 344.399 463.464 1.00 48.29  ? 189 TYR A N   1 
ATOM 2808 C CA  . TYR C 3 189 ? 372.164 344.684 464.835 1.00 48.29  ? 189 TYR A CA  1 
ATOM 2809 C C   . TYR C 3 189 ? 371.378 345.888 465.332 1.00 48.29  ? 189 TYR A C   1 
ATOM 2810 O O   . TYR C 3 189 ? 371.323 346.932 464.685 1.00 48.29  ? 189 TYR A O   1 
ATOM 2811 C CB  . TYR C 3 189 ? 373.653 344.986 464.957 1.00 48.29  ? 189 TYR A CB  1 
ATOM 2812 C CG  . TYR C 3 189 ? 374.595 343.884 464.555 1.00 48.29  ? 189 TYR A CG  1 
ATOM 2813 C CD1 . TYR C 3 189 ? 374.654 342.702 465.263 1.00 48.29  ? 189 TYR A CD1 1 
ATOM 2814 C CD2 . TYR C 3 189 ? 375.459 344.051 463.492 1.00 48.29  ? 189 TYR A CD2 1 
ATOM 2815 C CE1 . TYR C 3 189 ? 375.524 341.707 464.906 1.00 48.29  ? 189 TYR A CE1 1 
ATOM 2816 C CE2 . TYR C 3 189 ? 376.335 343.068 463.133 1.00 48.29  ? 189 TYR A CE2 1 
ATOM 2817 C CZ  . TYR C 3 189 ? 376.361 341.897 463.839 1.00 48.29  ? 189 TYR A CZ  1 
ATOM 2818 O OH  . TYR C 3 189 ? 377.238 340.909 463.477 1.00 48.29  ? 189 TYR A OH  1 
ATOM 2819 N N   . SER C 3 190 ? 370.792 345.756 466.513 1.00 49.13  ? 190 SER A N   1 
ATOM 2820 C CA  . SER C 3 190 ? 369.936 346.804 467.057 1.00 49.13  ? 190 SER A CA  1 
ATOM 2821 C C   . SER C 3 190 ? 370.710 347.534 468.139 1.00 49.13  ? 190 SER A C   1 
ATOM 2822 O O   . SER C 3 190 ? 370.987 346.964 469.197 1.00 49.13  ? 190 SER A O   1 
ATOM 2823 C CB  . SER C 3 190 ? 368.643 346.226 467.617 1.00 49.13  ? 190 SER A CB  1 
ATOM 2824 O OG  . SER C 3 190 ? 368.890 345.577 468.848 1.00 49.13  ? 190 SER A OG  1 
ATOM 2825 N N   . CYS C 3 191 ? 371.057 348.791 467.876 1.00 51.19  ? 191 CYS A N   1 
ATOM 2826 C CA  . CYS C 3 191 ? 371.814 349.564 468.848 1.00 51.19  ? 191 CYS A CA  1 
ATOM 2827 C C   . CYS C 3 191 ? 370.957 349.999 470.026 1.00 51.19  ? 191 CYS A C   1 
ATOM 2828 O O   . CYS C 3 191 ? 371.486 350.219 471.119 1.00 51.19  ? 191 CYS A O   1 
ATOM 2829 C CB  . CYS C 3 191 ? 372.436 350.779 468.170 1.00 51.19  ? 191 CYS A CB  1 
ATOM 2830 S SG  . CYS C 3 191 ? 373.924 350.398 467.237 1.00 51.19  ? 191 CYS A SG  1 
ATOM 2831 N N   . PHE C 3 192 ? 369.646 350.113 469.833 1.00 49.76  ? 192 PHE A N   1 
ATOM 2832 C CA  . PHE C 3 192 ? 368.719 350.517 470.879 1.00 49.76  ? 192 PHE A CA  1 
ATOM 2833 C C   . PHE C 3 192 ? 367.557 349.540 470.918 1.00 49.76  ? 192 PHE A C   1 
ATOM 2834 O O   . PHE C 3 192 ? 366.922 349.284 469.893 1.00 49.76  ? 192 PHE A O   1 
ATOM 2835 C CB  . PHE C 3 192 ? 368.195 351.924 470.635 1.00 49.76  ? 192 PHE A CB  1 
ATOM 2836 C CG  . PHE C 3 192 ? 369.215 352.999 470.841 1.00 49.76  ? 192 PHE A CG  1 
ATOM 2837 C CD1 . PHE C 3 192 ? 370.071 353.365 469.823 1.00 49.76  ? 192 PHE A CD1 1 
ATOM 2838 C CD2 . PHE C 3 192 ? 369.302 353.657 472.048 1.00 49.76  ? 192 PHE A CD2 1 
ATOM 2839 C CE1 . PHE C 3 192 ? 371.000 354.355 470.012 1.00 49.76  ? 192 PHE A CE1 1 
ATOM 2840 C CE2 . PHE C 3 192 ? 370.229 354.645 472.242 1.00 49.76  ? 192 PHE A CE2 1 
ATOM 2841 C CZ  . PHE C 3 192 ? 371.077 354.994 471.222 1.00 49.76  ? 192 PHE A CZ  1 
ATOM 2842 N N   . TYR C 3 193 ? 367.265 349.008 472.103 1.00 52.19  ? 193 TYR A N   1 
ATOM 2843 C CA  . TYR C 3 193 ? 366.248 347.971 472.262 1.00 52.19  ? 193 TYR A CA  1 
ATOM 2844 C C   . TYR C 3 193 ? 365.393 348.305 473.474 1.00 52.19  ? 193 TYR A C   1 
ATOM 2845 O O   . TYR C 3 193 ? 365.825 348.093 474.608 1.00 52.19  ? 193 TYR A O   1 
ATOM 2846 C CB  . TYR C 3 193 ? 366.899 346.603 472.423 1.00 52.19  ? 193 TYR A CB  1 
ATOM 2847 C CG  . TYR C 3 193 ? 365.939 345.470 472.670 1.00 52.19  ? 193 TYR A CG  1 
ATOM 2848 C CD1 . TYR C 3 193 ? 365.195 344.934 471.637 1.00 52.19  ? 193 TYR A CD1 1 
ATOM 2849 C CD2 . TYR C 3 193 ? 365.801 344.919 473.931 1.00 52.19  ? 193 TYR A CD2 1 
ATOM 2850 C CE1 . TYR C 3 193 ? 364.326 343.897 471.858 1.00 52.19  ? 193 TYR A CE1 1 
ATOM 2851 C CE2 . TYR C 3 193 ? 364.938 343.882 474.159 1.00 52.19  ? 193 TYR A CE2 1 
ATOM 2852 C CZ  . TYR C 3 193 ? 364.203 343.377 473.120 1.00 52.19  ? 193 TYR A CZ  1 
ATOM 2853 O OH  . TYR C 3 193 ? 363.336 342.339 473.342 1.00 52.19  ? 193 TYR A OH  1 
ATOM 2854 N N   . ASP C 3 194 ? 364.180 348.807 473.240 1.00 54.08  ? 194 ASP A N   1 
ATOM 2855 C CA  . ASP C 3 194 ? 363.265 349.169 474.321 1.00 54.08  ? 194 ASP A CA  1 
ATOM 2856 C C   . ASP C 3 194 ? 362.441 347.945 474.693 1.00 54.08  ? 194 ASP A C   1 
ATOM 2857 O O   . ASP C 3 194 ? 361.375 347.690 474.144 1.00 54.08  ? 194 ASP A O   1 
ATOM 2858 C CB  . ASP C 3 194 ? 362.368 350.326 473.910 1.00 54.08  ? 194 ASP A CB  1 
ATOM 2859 C CG  . ASP C 3 194 ? 361.568 350.891 475.075 1.00 54.08  ? 194 ASP A CG  1 
ATOM 2860 O OD1 . ASP C 3 194 ? 361.878 350.567 476.239 1.00 54.08  ? 194 ASP A OD1 1 
ATOM 2861 O OD2 . ASP C 3 194 ? 360.626 351.668 474.826 1.00 54.08  ? 194 ASP A OD2 1 
ATOM 2862 N N   . GLY C 3 195 ? 362.939 347.194 475.663 1.00 51.99  ? 195 GLY A N   1 
ATOM 2863 C CA  . GLY C 3 195 ? 362.244 346.001 476.091 1.00 51.99  ? 195 GLY A CA  1 
ATOM 2864 C C   . GLY C 3 195 ? 363.134 345.161 476.974 1.00 51.99  ? 195 GLY A C   1 
ATOM 2865 O O   . GLY C 3 195 ? 364.189 345.601 477.433 1.00 51.99  ? 195 GLY A O   1 
ATOM 2866 N N   . TRP C 3 196 ? 362.681 343.940 477.205 1.00 52.70  ? 196 TRP A N   1 
ATOM 2867 C CA  . TRP C 3 196 ? 363.390 342.980 478.031 1.00 52.70  ? 196 TRP A CA  1 
ATOM 2868 C C   . TRP C 3 196 ? 363.864 341.813 477.178 1.00 52.70  ? 196 TRP A C   1 
ATOM 2869 O O   . TRP C 3 196 ? 363.507 341.685 476.008 1.00 52.70  ? 196 TRP A O   1 
ATOM 2870 C CB  . TRP C 3 196 ? 362.495 342.483 479.163 1.00 52.70  ? 196 TRP A CB  1 
ATOM 2871 C CG  . TRP C 3 196 ? 362.273 343.506 480.212 1.00 52.70  ? 196 TRP A CG  1 
ATOM 2872 C CD1 . TRP C 3 196 ? 362.926 343.611 481.399 1.00 52.70  ? 196 TRP A CD1 1 
ATOM 2873 C CD2 . TRP C 3 196 ? 361.337 344.583 480.173 1.00 52.70  ? 196 TRP A CD2 1 
ATOM 2874 N NE1 . TRP C 3 196 ? 362.453 344.686 482.105 1.00 52.70  ? 196 TRP A NE1 1 
ATOM 2875 C CE2 . TRP C 3 196 ? 361.477 345.300 481.369 1.00 52.70  ? 196 TRP A CE2 1 
ATOM 2876 C CE3 . TRP C 3 196 ? 360.392 345.009 479.242 1.00 52.70  ? 196 TRP A CE3 1 
ATOM 2877 C CZ2 . TRP C 3 196 ? 360.713 346.417 481.655 1.00 52.70  ? 196 TRP A CZ2 1 
ATOM 2878 C CZ3 . TRP C 3 196 ? 359.638 346.116 479.529 1.00 52.70  ? 196 TRP A CZ3 1 
ATOM 2879 C CH2 . TRP C 3 196 ? 359.803 346.809 480.722 1.00 52.70  ? 196 TRP A CH2 1 
ATOM 2880 N N   . THR C 3 197 ? 364.676 340.957 477.779 1.00 50.32  ? 197 THR A N   1 
ATOM 2881 C CA  . THR C 3 197 ? 365.264 339.844 477.054 1.00 50.32  ? 197 THR A CA  1 
ATOM 2882 C C   . THR C 3 197 ? 364.270 338.711 476.838 1.00 50.32  ? 197 THR A C   1 
ATOM 2883 O O   . THR C 3 197 ? 364.128 338.195 475.728 1.00 50.32  ? 197 THR A O   1 
ATOM 2884 C CB  . THR C 3 197 ? 366.474 339.303 477.789 1.00 50.32  ? 197 THR A CB  1 
ATOM 2885 O OG1 . THR C 3 197 ? 367.043 338.230 477.036 1.00 50.32  ? 197 THR A OG1 1 
ATOM 2886 C CG2 . THR C 3 197 ? 366.058 338.792 479.137 1.00 50.32  ? 197 THR A CG2 1 
ATOM 2887 N N   . VAL C 3 204 ? 365.956 341.239 482.103 1.00 52.96  ? 204 VAL A N   1 
ATOM 2888 C CA  . VAL C 3 204 ? 366.812 342.392 482.352 1.00 52.96  ? 204 VAL A CA  1 
ATOM 2889 C C   . VAL C 3 204 ? 366.625 343.414 481.223 1.00 52.96  ? 204 VAL A C   1 
ATOM 2890 O O   . VAL C 3 204 ? 366.519 343.055 480.056 1.00 52.96  ? 204 VAL A O   1 
ATOM 2891 C CB  . VAL C 3 204 ? 368.281 341.940 482.545 1.00 52.96  ? 204 VAL A CB  1 
ATOM 2892 C CG1 . VAL C 3 204 ? 368.782 341.144 481.355 1.00 52.96  ? 204 VAL A CG1 1 
ATOM 2893 C CG2 . VAL C 3 204 ? 369.188 343.116 482.840 1.00 52.96  ? 204 VAL A CG2 1 
ATOM 2894 N N   . TYR C 3 205 ? 366.542 344.692 481.588 1.00 52.48  ? 205 TYR A N   1 
ATOM 2895 C CA  . TYR C 3 205 ? 366.007 345.711 480.696 1.00 52.48  ? 205 TYR A CA  1 
ATOM 2896 C C   . TYR C 3 205 ? 367.030 346.148 479.662 1.00 52.48  ? 205 TYR A C   1 
ATOM 2897 O O   . TYR C 3 205 ? 368.168 346.478 480.002 1.00 52.48  ? 205 TYR A O   1 
ATOM 2898 C CB  . TYR C 3 205 ? 365.541 346.924 481.497 1.00 52.48  ? 205 TYR A CB  1 
ATOM 2899 C CG  . TYR C 3 205 ? 364.995 348.033 480.638 1.00 52.48  ? 205 TYR A CG  1 
ATOM 2900 C CD1 . TYR C 3 205 ? 363.792 347.892 479.976 1.00 52.48  ? 205 TYR A CD1 1 
ATOM 2901 C CD2 . TYR C 3 205 ? 365.686 349.221 480.489 1.00 52.48  ? 205 TYR A CD2 1 
ATOM 2902 C CE1 . TYR C 3 205 ? 363.292 348.900 479.189 1.00 52.48  ? 205 TYR A CE1 1 
ATOM 2903 C CE2 . TYR C 3 205 ? 365.196 350.234 479.700 1.00 52.48  ? 205 TYR A CE2 1 
ATOM 2904 C CZ  . TYR C 3 205 ? 363.999 350.067 479.056 1.00 52.48  ? 205 TYR A CZ  1 
ATOM 2905 O OH  . TYR C 3 205 ? 363.507 351.078 478.272 1.00 52.48  ? 205 TYR A OH  1 
ATOM 2906 N N   . GLY C 3 206 ? 366.606 346.167 478.403 1.00 52.16  ? 206 GLY A N   1 
ATOM 2907 C CA  . GLY C 3 206 ? 367.378 346.724 477.312 1.00 52.16  ? 206 GLY A CA  1 
ATOM 2908 C C   . GLY C 3 206 ? 368.672 346.008 477.002 1.00 52.16  ? 206 GLY A C   1 
ATOM 2909 O O   . GLY C 3 206 ? 369.712 346.656 476.875 1.00 52.16  ? 206 GLY A O   1 
ATOM 2910 N N   . ILE C 3 207 ? 368.634 344.686 476.875 1.00 51.03  ? 207 ILE A N   1 
ATOM 2911 C CA  . ILE C 3 207 ? 369.831 343.887 476.658 1.00 51.03  ? 207 ILE A CA  1 
ATOM 2912 C C   . ILE C 3 207 ? 369.859 343.283 475.259 1.00 51.03  ? 207 ILE A C   1 
ATOM 2913 O O   . ILE C 3 207 ? 370.815 343.503 474.513 1.00 51.03  ? 207 ILE A O   1 
ATOM 2914 C CB  . ILE C 3 207 ? 369.983 342.802 477.745 1.00 51.03  ? 207 ILE A CB  1 
ATOM 2915 C CG1 . ILE C 3 207 ? 370.519 343.442 479.020 1.00 51.03  ? 207 ILE A CG1 1 
ATOM 2916 C CG2 . ILE C 3 207 ? 370.948 341.720 477.314 1.00 51.03  ? 207 ILE A CG2 1 
ATOM 2917 C CD1 . ILE C 3 207 ? 371.872 344.067 478.865 1.00 51.03  ? 207 ILE A CD1 1 
ATOM 2918 N N   . ASN C 3 208 ? 368.810 342.533 474.883 1.00 50.06  ? 208 ASN A N   1 
ATOM 2919 C CA  . ASN C 3 208 ? 368.661 341.926 473.557 1.00 50.06  ? 208 ASN A CA  1 
ATOM 2920 C C   . ASN C 3 208 ? 369.812 341.002 473.187 1.00 50.06  ? 208 ASN A C   1 
ATOM 2921 O O   . ASN C 3 208 ? 370.702 341.399 472.438 1.00 50.06  ? 208 ASN A O   1 
ATOM 2922 C CB  . ASN C 3 208 ? 368.482 342.973 472.452 1.00 50.06  ? 208 ASN A CB  1 
ATOM 2923 C CG  . ASN C 3 208 ? 368.123 342.352 471.118 1.00 50.06  ? 208 ASN A CG  1 
ATOM 2924 O OD1 . ASN C 3 208 ? 367.544 341.271 471.063 1.00 50.06  ? 208 ASN A OD1 1 
ATOM 2925 N ND2 . ASN C 3 208 ? 368.471 343.030 470.036 1.00 50.06  ? 208 ASN A ND2 1 
ATOM 2926 N N   . THR C 3 209 ? 369.854 339.794 473.744 1.00 51.20  ? 209 THR A N   1 
ATOM 2927 C CA  . THR C 3 209 ? 370.883 338.809 473.407 1.00 51.20  ? 209 THR A CA  1 
ATOM 2928 C C   . THR C 3 209 ? 370.930 338.353 471.945 1.00 51.20  ? 209 THR A C   1 
ATOM 2929 O O   . THR C 3 209 ? 371.771 337.526 471.590 1.00 51.20  ? 209 THR A O   1 
ATOM 2930 C CB  . THR C 3 209 ? 370.699 337.574 474.281 1.00 51.20  ? 209 THR A CB  1 
ATOM 2931 O OG1 . THR C 3 209 ? 369.364 337.082 474.122 1.00 51.20  ? 209 THR A OG1 1 
ATOM 2932 C CG2 . THR C 3 209 ? 370.938 337.918 475.737 1.00 51.20  ? 209 THR A CG2 1 
ATOM 2933 N N   . LEU C 3 210 ? 370.038 338.850 471.094 1.00 50.21  ? 210 LEU A N   1 
ATOM 2934 C CA  . LEU C 3 210 ? 370.038 338.510 469.682 1.00 50.21  ? 210 LEU A CA  1 
ATOM 2935 C C   . LEU C 3 210 ? 371.173 339.157 468.909 1.00 50.21  ? 210 LEU A C   1 
ATOM 2936 O O   . LEU C 3 210 ? 371.554 338.637 467.858 1.00 50.21  ? 210 LEU A O   1 
ATOM 2937 C CB  . LEU C 3 210 ? 368.705 338.908 469.052 1.00 50.21  ? 210 LEU A CB  1 
ATOM 2938 C CG  . LEU C 3 210 ? 368.223 338.114 467.844 1.00 50.21  ? 210 LEU A CG  1 
ATOM 2939 C CD1 . LEU C 3 210 ? 368.161 336.644 468.165 1.00 50.21  ? 210 LEU A CD1 1 
ATOM 2940 C CD2 . LEU C 3 210 ? 366.863 338.614 467.432 1.00 50.21  ? 210 LEU A CD2 1 
ATOM 2941 N N   . ASN C 3 211 ? 371.723 340.282 469.367 1.00 50.90  ? 211 ASN A N   1 
ATOM 2942 C CA  . ASN C 3 211 ? 372.933 340.817 468.740 1.00 50.90  ? 211 ASN A CA  1 
ATOM 2943 C C   . ASN C 3 211 ? 374.118 340.560 469.673 1.00 50.90  ? 211 ASN A C   1 
ATOM 2944 O O   . ASN C 3 211 ? 374.580 341.422 470.416 1.00 50.90  ? 211 ASN A O   1 
ATOM 2945 C CB  . ASN C 3 211 ? 372.778 342.279 468.306 1.00 50.90  ? 211 ASN A CB  1 
ATOM 2946 C CG  . ASN C 3 211 ? 372.344 343.219 469.407 1.00 50.90  ? 211 ASN A CG  1 
ATOM 2947 O OD1 . ASN C 3 211 ? 372.180 342.841 470.549 1.00 50.90  ? 211 ASN A OD1 1 
ATOM 2948 N ND2 . ASN C 3 211 ? 372.180 344.480 469.049 1.00 50.90  ? 211 ASN A ND2 1 
ATOM 2949 N N   . ASN C 3 212 ? 374.638 339.347 469.585 1.00 51.67  ? 212 ASN A N   1 
ATOM 2950 C CA  . ASN C 3 212 ? 375.787 338.911 470.357 1.00 51.67  ? 212 ASN A CA  1 
ATOM 2951 C C   . ASN C 3 212 ? 376.783 338.356 469.354 1.00 51.67  ? 212 ASN A C   1 
ATOM 2952 O O   . ASN C 3 212 ? 376.474 337.397 468.642 1.00 51.67  ? 212 ASN A O   1 
ATOM 2953 C CB  . ASN C 3 212 ? 375.375 337.860 471.386 1.00 51.67  ? 212 ASN A CB  1 
ATOM 2954 C CG  . ASN C 3 212 ? 376.432 337.607 472.421 1.00 51.67  ? 212 ASN A CG  1 
ATOM 2955 O OD1 . ASN C 3 212 ? 377.538 338.133 472.341 1.00 51.67  ? 212 ASN A OD1 1 
ATOM 2956 N ND2 . ASN C 3 212 ? 376.097 336.801 473.413 1.00 51.67  ? 212 ASN A ND2 1 
ATOM 2957 N N   . MET C 3 213 ? 377.959 338.973 469.272 1.00 49.77  ? 213 MET A N   1 
ATOM 2958 C CA  . MET C 3 213 ? 378.875 338.680 468.182 1.00 49.77  ? 213 MET A CA  1 
ATOM 2959 C C   . MET C 3 213 ? 379.949 337.666 468.536 1.00 49.77  ? 213 MET A C   1 
ATOM 2960 O O   . MET C 3 213 ? 380.608 337.150 467.628 1.00 49.77  ? 213 MET A O   1 
ATOM 2961 C CB  . MET C 3 213 ? 379.539 339.966 467.694 1.00 49.77  ? 213 MET A CB  1 
ATOM 2962 C CG  . MET C 3 213 ? 378.548 341.067 467.437 1.00 49.77  ? 213 MET A CG  1 
ATOM 2963 S SD  . MET C 3 213 ? 379.280 342.680 467.144 1.00 49.77  ? 213 MET A SD  1 
ATOM 2964 C CE  . MET C 3 213 ? 377.900 343.729 467.582 1.00 49.77  ? 213 MET A CE  1 
ATOM 2965 N N   . GLY C 3 214 ? 380.143 337.358 469.811 1.00 46.68  ? 214 GLY A N   1 
ATOM 2966 C CA  . GLY C 3 214 ? 381.108 336.336 470.160 1.00 46.68  ? 214 GLY A CA  1 
ATOM 2967 C C   . GLY C 3 214 ? 382.159 336.821 471.127 1.00 46.68  ? 214 GLY A C   1 
ATOM 2968 O O   . GLY C 3 214 ? 382.063 337.940 471.628 1.00 46.68  ? 214 GLY A O   1 
ATOM 2969 N N   . THR C 3 215 ? 383.168 335.999 471.398 1.00 44.20  ? 215 THR A N   1 
ATOM 2970 C CA  . THR C 3 215 ? 384.172 336.308 472.402 1.00 44.20  ? 215 THR A CA  1 
ATOM 2971 C C   . THR C 3 215 ? 385.531 335.862 471.877 1.00 44.20  ? 215 THR A C   1 
ATOM 2972 O O   . THR C 3 215 ? 385.620 334.901 471.116 1.00 44.20  ? 215 THR A O   1 
ATOM 2973 C CB  . THR C 3 215 ? 383.820 335.614 473.726 1.00 44.20  ? 215 THR A CB  1 
ATOM 2974 O OG1 . THR C 3 215 ? 382.450 335.871 474.044 1.00 44.20  ? 215 THR A OG1 1 
ATOM 2975 C CG2 . THR C 3 215 ? 384.640 336.153 474.862 1.00 44.20  ? 215 THR A CG2 1 
ATOM 2976 N N   . LEU C 3 216 ? 386.587 336.573 472.266 1.00 44.98  ? 216 LEU A N   1 
ATOM 2977 C CA  . LEU C 3 216 ? 387.945 336.275 471.840 1.00 44.98  ? 216 LEU A CA  1 
ATOM 2978 C C   . LEU C 3 216 ? 388.823 335.971 473.043 1.00 44.98  ? 216 LEU A C   1 
ATOM 2979 O O   . LEU C 3 216 ? 388.794 336.691 474.041 1.00 44.98  ? 216 LEU A O   1 
ATOM 2980 C CB  . LEU C 3 216 ? 388.545 337.447 471.076 1.00 44.98  ? 216 LEU A CB  1 
ATOM 2981 C CG  . LEU C 3 216 ? 387.985 337.745 469.695 1.00 44.98  ? 216 LEU A CG  1 
ATOM 2982 C CD1 . LEU C 3 216 ? 388.052 339.219 469.457 1.00 44.98  ? 216 LEU A CD1 1 
ATOM 2983 C CD2 . LEU C 3 216 ? 388.789 337.020 468.647 1.00 44.98  ? 216 LEU A CD2 1 
ATOM 2984 N N   . TYR C 3 217 ? 389.625 334.915 472.938 1.00 46.11  ? 217 TYR A N   1 
ATOM 2985 C CA  . TYR C 3 217 ? 390.550 334.541 473.998 1.00 46.11  ? 217 TYR A CA  1 
ATOM 2986 C C   . TYR C 3 217 ? 391.938 334.346 473.416 1.00 46.11  ? 217 TYR A C   1 
ATOM 2987 O O   . TYR C 3 217 ? 392.083 333.849 472.298 1.00 46.11  ? 217 TYR A O   1 
ATOM 2988 C CB  . TYR C 3 217 ? 390.113 333.264 474.706 1.00 46.11  ? 217 TYR A CB  1 
ATOM 2989 C CG  . TYR C 3 217 ? 388.778 333.375 475.372 1.00 46.11  ? 217 TYR A CG  1 
ATOM 2990 C CD1 . TYR C 3 217 ? 388.664 333.904 476.642 1.00 46.11  ? 217 TYR A CD1 1 
ATOM 2991 C CD2 . TYR C 3 217 ? 387.629 332.951 474.731 1.00 46.11  ? 217 TYR A CD2 1 
ATOM 2992 C CE1 . TYR C 3 217 ? 387.443 334.013 477.255 1.00 46.11  ? 217 TYR A CE1 1 
ATOM 2993 C CE2 . TYR C 3 217 ? 386.407 333.060 475.334 1.00 46.11  ? 217 TYR A CE2 1 
ATOM 2994 C CZ  . TYR C 3 217 ? 386.324 333.591 476.596 1.00 46.11  ? 217 TYR A CZ  1 
ATOM 2995 O OH  . TYR C 3 217 ? 385.106 333.705 477.201 1.00 46.11  ? 217 TYR A OH  1 
ATOM 2996 N N   . MET C 3 218 ? 392.958 334.727 474.182 1.00 47.63  ? 218 MET A N   1 
ATOM 2997 C CA  . MET C 3 218 ? 394.335 334.724 473.717 1.00 47.63  ? 218 MET A CA  1 
ATOM 2998 C C   . MET C 3 218 ? 395.242 334.113 474.771 1.00 47.63  ? 218 MET A C   1 
ATOM 2999 O O   . MET C 3 218 ? 395.036 334.329 475.966 1.00 47.63  ? 218 MET A O   1 
ATOM 3000 C CB  . MET C 3 218 ? 394.800 336.137 473.399 1.00 47.63  ? 218 MET A CB  1 
ATOM 3001 C CG  . MET C 3 218 ? 394.260 336.686 472.103 1.00 47.63  ? 218 MET A CG  1 
ATOM 3002 S SD  . MET C 3 218 ? 393.809 338.417 472.234 1.00 47.63  ? 218 MET A SD  1 
ATOM 3003 C CE  . MET C 3 218 ? 392.045 338.301 472.478 1.00 47.63  ? 218 MET A CE  1 
ATOM 3004 N N   . ARG C 3 219 ? 396.250 333.364 474.326 1.00 47.11  ? 219 ARG A N   1 
ATOM 3005 C CA  . ARG C 3 219 ? 397.206 332.734 475.229 1.00 47.11  ? 219 ARG A CA  1 
ATOM 3006 C C   . ARG C 3 219 ? 398.465 332.365 474.459 1.00 47.11  ? 219 ARG A C   1 
ATOM 3007 O O   . ARG C 3 219 ? 398.465 332.279 473.231 1.00 47.11  ? 219 ARG A O   1 
ATOM 3008 C CB  . ARG C 3 219 ? 396.622 331.487 475.888 1.00 47.11  ? 219 ARG A CB  1 
ATOM 3009 C CG  . ARG C 3 219 ? 396.404 330.370 474.912 1.00 47.11  ? 219 ARG A CG  1 
ATOM 3010 C CD  . ARG C 3 219 ? 396.429 329.014 475.559 1.00 47.11  ? 219 ARG A CD  1 
ATOM 3011 N NE  . ARG C 3 219 ? 396.373 327.981 474.538 1.00 47.11  ? 219 ARG A NE  1 
ATOM 3012 C CZ  . ARG C 3 219 ? 396.244 326.689 474.791 1.00 47.11  ? 219 ARG A CZ  1 
ATOM 3013 N NH1 . ARG C 3 219 ? 396.151 326.264 476.037 1.00 47.11  ? 219 ARG A NH1 1 
ATOM 3014 N NH2 . ARG C 3 219 ? 396.201 325.826 473.791 1.00 47.11  ? 219 ARG A NH2 1 
ATOM 3015 N N   . HIS C 3 220 ? 399.545 332.149 475.204 1.00 49.26  ? 220 HIS A N   1 
ATOM 3016 C CA  . HIS C 3 220 ? 400.751 331.549 474.656 1.00 49.26  ? 220 HIS A CA  1 
ATOM 3017 C C   . HIS C 3 220 ? 400.539 330.055 474.453 1.00 49.26  ? 220 HIS A C   1 
ATOM 3018 O O   . HIS C 3 220 ? 399.762 329.421 475.169 1.00 49.26  ? 220 HIS A O   1 
ATOM 3019 C CB  . HIS C 3 220 ? 401.937 331.739 475.600 1.00 49.26  ? 220 HIS A CB  1 
ATOM 3020 C CG  . HIS C 3 220 ? 402.383 333.155 475.763 1.00 49.26  ? 220 HIS A CG  1 
ATOM 3021 N ND1 . HIS C 3 220 ? 401.867 333.989 476.728 1.00 49.26  ? 220 HIS A ND1 1 
ATOM 3022 C CD2 . HIS C 3 220 ? 403.330 333.871 475.115 1.00 49.26  ? 220 HIS A CD2 1 
ATOM 3023 C CE1 . HIS C 3 220 ? 402.462 335.165 476.654 1.00 49.26  ? 220 HIS A CE1 1 
ATOM 3024 N NE2 . HIS C 3 220 ? 403.351 335.121 475.681 1.00 49.26  ? 220 HIS A NE2 1 
ATOM 3025 N N   . VAL C 3 221 ? 401.252 329.478 473.488 1.00 49.72  ? 221 VAL A N   1 
ATOM 3026 C CA  . VAL C 3 221 ? 401.303 328.027 473.366 1.00 49.72  ? 221 VAL A CA  1 
ATOM 3027 C C   . VAL C 3 221 ? 402.669 327.469 473.716 1.00 49.72  ? 221 VAL A C   1 
ATOM 3028 O O   . VAL C 3 221 ? 402.800 326.253 473.901 1.00 49.72  ? 221 VAL A O   1 
ATOM 3029 C CB  . VAL C 3 221 ? 400.876 327.548 471.966 1.00 49.72  ? 221 VAL A CB  1 
ATOM 3030 C CG1 . VAL C 3 221 ? 399.624 328.245 471.515 1.00 49.72  ? 221 VAL A CG1 1 
ATOM 3031 C CG2 . VAL C 3 221 ? 401.974 327.728 470.971 1.00 49.72  ? 221 VAL A CG2 1 
ATOM 3032 N N   . ASN C 3 222 ? 403.689 328.313 473.822 1.00 56.17  ? 222 ASN A N   1 
ATOM 3033 C CA  . ASN C 3 222 ? 405.033 327.886 474.175 1.00 56.17  ? 222 ASN A CA  1 
ATOM 3034 C C   . ASN C 3 222 ? 405.144 327.753 475.683 1.00 56.17  ? 222 ASN A C   1 
ATOM 3035 O O   . ASN C 3 222 ? 404.827 328.694 476.416 1.00 56.17  ? 222 ASN A O   1 
ATOM 3036 C CB  . ASN C 3 222 ? 406.069 328.885 473.670 1.00 56.17  ? 222 ASN A CB  1 
ATOM 3037 C CG  . ASN C 3 222 ? 406.331 328.756 472.196 1.00 56.17  ? 222 ASN A CG  1 
ATOM 3038 O OD1 . ASN C 3 222 ? 405.870 329.565 471.401 1.00 56.17  ? 222 ASN A OD1 1 
ATOM 3039 N ND2 . ASN C 3 222 ? 407.095 327.748 471.820 1.00 56.17  ? 222 ASN A ND2 1 
ATOM 3040 N N   . GLU C 3 223 ? 405.592 326.593 476.144 1.00 68.48  ? 223 GLU A N   1 
ATOM 3041 C CA  . GLU C 3 223 ? 405.953 326.417 477.542 1.00 68.48  ? 223 GLU A CA  1 
ATOM 3042 C C   . GLU C 3 223 ? 407.332 327.018 477.756 1.00 68.48  ? 223 GLU A C   1 
ATOM 3043 O O   . GLU C 3 223 ? 408.264 326.710 477.011 1.00 68.48  ? 223 GLU A O   1 
ATOM 3044 C CB  . GLU C 3 223 ? 405.952 324.941 477.926 1.00 68.48  ? 223 GLU A CB  1 
ATOM 3045 C CG  . GLU C 3 223 ? 406.301 324.689 479.379 1.00 68.48  ? 223 GLU A CG  1 
ATOM 3046 C CD  . GLU C 3 223 ? 405.075 324.626 480.269 1.00 68.48  ? 223 GLU A CD  1 
ATOM 3047 O OE1 . GLU C 3 223 ? 405.234 324.587 481.506 1.00 68.48  ? 223 GLU A OE1 1 
ATOM 3048 O OE2 . GLU C 3 223 ? 403.949 324.622 479.730 1.00 68.48  ? 223 GLU A OE2 1 
ATOM 3049 N N   . ALA C 3 224 ? 407.462 327.875 478.761 1.00 70.38  ? 224 ALA A N   1 
ATOM 3050 C CA  . ALA C 3 224 ? 408.698 328.619 478.954 1.00 70.38  ? 224 ALA A CA  1 
ATOM 3051 C C   . ALA C 3 224 ? 409.308 328.240 480.287 1.00 70.38  ? 224 ALA A C   1 
ATOM 3052 O O   . ALA C 3 224 ? 408.587 328.094 481.277 1.00 70.38  ? 224 ALA A O   1 
ATOM 3053 C CB  . ALA C 3 224 ? 408.456 330.128 478.900 1.00 70.38  ? 224 ALA A CB  1 
ATOM 3054 N N   . GLY C 3 225 ? 410.630 328.096 480.312 1.00 75.98  ? 225 GLY A N   1 
ATOM 3055 C CA  . GLY C 3 225 ? 411.290 327.611 481.506 1.00 75.98  ? 225 GLY A CA  1 
ATOM 3056 C C   . GLY C 3 225 ? 412.195 328.587 482.230 1.00 75.98  ? 225 GLY A C   1 
ATOM 3057 O O   . GLY C 3 225 ? 412.257 328.573 483.462 1.00 75.98  ? 225 GLY A O   1 
ATOM 3058 N N   . GLN C 3 226 ? 412.894 329.450 481.493 1.00 77.67  ? 226 GLN A N   1 
ATOM 3059 C CA  . GLN C 3 226 ? 413.944 330.240 482.125 1.00 77.67  ? 226 GLN A CA  1 
ATOM 3060 C C   . GLN C 3 226 ? 413.540 331.688 482.359 1.00 77.67  ? 226 GLN A C   1 
ATOM 3061 O O   . GLN C 3 226 ? 414.057 332.323 483.281 1.00 77.67  ? 226 GLN A O   1 
ATOM 3062 C CB  . GLN C 3 226 ? 415.216 330.185 481.284 1.00 77.67  ? 226 GLN A CB  1 
ATOM 3063 C CG  . GLN C 3 226 ? 415.637 328.783 480.933 1.00 77.67  ? 226 GLN A CG  1 
ATOM 3064 C CD  . GLN C 3 226 ? 416.027 327.976 482.146 1.00 77.67  ? 226 GLN A CD  1 
ATOM 3065 O OE1 . GLN C 3 226 ? 415.215 327.246 482.712 1.00 77.67  ? 226 GLN A OE1 1 
ATOM 3066 N NE2 . GLN C 3 226 ? 417.283 328.096 482.550 1.00 77.67  ? 226 GLN A NE2 1 
ATOM 3067 N N   . GLY C 3 227 ? 412.635 332.229 481.557 1.00 69.39  ? 227 GLY A N   1 
ATOM 3068 C CA  . GLY C 3 227 ? 412.284 333.618 481.688 1.00 69.39  ? 227 GLY A CA  1 
ATOM 3069 C C   . GLY C 3 227 ? 410.802 333.868 481.537 1.00 69.39  ? 227 GLY A C   1 
ATOM 3070 O O   . GLY C 3 227 ? 410.159 333.389 480.599 1.00 69.39  ? 227 GLY A O   1 
ATOM 3071 N N   . PRO C 3 228 ? 410.226 334.614 482.475 1.00 63.20  ? 228 PRO A N   1 
ATOM 3072 C CA  . PRO C 3 228 ? 408.841 335.052 482.308 1.00 63.20  ? 228 PRO A CA  1 
ATOM 3073 C C   . PRO C 3 228 ? 408.744 336.090 481.208 1.00 63.20  ? 228 PRO A C   1 
ATOM 3074 O O   . PRO C 3 228 ? 409.610 336.953 481.067 1.00 63.20  ? 228 PRO A O   1 
ATOM 3075 C CB  . PRO C 3 228 ? 408.490 335.647 483.674 1.00 63.20  ? 228 PRO A CB  1 
ATOM 3076 C CG  . PRO C 3 228 ? 409.499 335.084 484.607 1.00 63.20  ? 228 PRO A CG  1 
ATOM 3077 C CD  . PRO C 3 228 ? 410.742 334.955 483.806 1.00 63.20  ? 228 PRO A CD  1 
ATOM 3078 N N   . ILE C 3 229 ? 407.684 335.989 480.417 1.00 57.67  ? 229 ILE A N   1 
ATOM 3079 C CA  . ILE C 3 229 ? 407.456 336.869 479.280 1.00 57.67  ? 229 ILE A CA  1 
ATOM 3080 C C   . ILE C 3 229 ? 406.011 337.326 479.337 1.00 57.67  ? 229 ILE A C   1 
ATOM 3081 O O   . ILE C 3 229 ? 405.100 336.495 479.374 1.00 57.67  ? 229 ILE A O   1 
ATOM 3082 C CB  . ILE C 3 229 ? 407.750 336.155 477.945 1.00 57.67  ? 229 ILE A CB  1 
ATOM 3083 C CG1 . ILE C 3 229 ? 409.253 336.034 477.719 1.00 57.67  ? 229 ILE A CG1 1 
ATOM 3084 C CG2 . ILE C 3 229 ? 407.125 336.887 476.779 1.00 57.67  ? 229 ILE A CG2 1 
ATOM 3085 C CD1 . ILE C 3 229 ? 409.624 335.394 476.397 1.00 57.67  ? 229 ILE A CD1 1 
ATOM 3086 N N   . LYS C 3 230 ? 405.793 338.633 479.368 1.00 52.46  ? 230 LYS A N   1 
ATOM 3087 C CA  . LYS C 3 230 ? 404.445 339.162 479.259 1.00 52.46  ? 230 LYS A CA  1 
ATOM 3088 C C   . LYS C 3 230 ? 404.257 339.799 477.889 1.00 52.46  ? 230 LYS A C   1 
ATOM 3089 O O   . LYS C 3 230 ? 405.196 340.317 477.281 1.00 52.46  ? 230 LYS A O   1 
ATOM 3090 C CB  . LYS C 3 230 ? 404.138 340.148 480.393 1.00 52.46  ? 230 LYS A CB  1 
ATOM 3091 C CG  . LYS C 3 230 ? 404.601 341.563 480.196 1.00 52.46  ? 230 LYS A CG  1 
ATOM 3092 C CD  . LYS C 3 230 ? 404.141 342.446 481.341 1.00 52.46  ? 230 LYS A CD  1 
ATOM 3093 C CE  . LYS C 3 230 ? 402.630 342.437 481.483 1.00 52.46  ? 230 LYS A CE  1 
ATOM 3094 N NZ  . LYS C 3 230 ? 402.145 343.537 482.360 1.00 52.46  ? 230 LYS A NZ  1 
ATOM 3095 N N   . SER C 3 231 ? 403.031 339.706 477.387 1.00 48.29  ? 231 SER A N   1 
ATOM 3096 C CA  . SER C 3 231 ? 402.713 340.073 476.018 1.00 48.29  ? 231 SER A CA  1 
ATOM 3097 C C   . SER C 3 231 ? 401.443 340.894 476.002 1.00 48.29  ? 231 SER A C   1 
ATOM 3098 O O   . SER C 3 231 ? 400.498 340.593 476.725 1.00 48.29  ? 231 SER A O   1 
ATOM 3099 C CB  . SER C 3 231 ? 402.518 338.840 475.145 1.00 48.29  ? 231 SER A CB  1 
ATOM 3100 O OG  . SER C 3 231 ? 403.499 337.864 475.421 1.00 48.29  ? 231 SER A OG  1 
ATOM 3101 N N   . THR C 3 232 ? 401.409 341.918 475.167 1.00 45.99  ? 232 THR A N   1 
ATOM 3102 C CA  . THR C 3 232 ? 400.252 342.793 475.103 1.00 45.99  ? 232 THR A CA  1 
ATOM 3103 C C   . THR C 3 232 ? 399.681 342.872 473.695 1.00 45.99  ? 232 THR A C   1 
ATOM 3104 O O   . THR C 3 232 ? 400.402 343.005 472.706 1.00 45.99  ? 232 THR A O   1 
ATOM 3105 C CB  . THR C 3 232 ? 400.608 344.188 475.617 1.00 45.99  ? 232 THR A CB  1 
ATOM 3106 O OG1 . THR C 3 232 ? 399.415 344.963 475.743 1.00 45.99  ? 232 THR A OG1 1 
ATOM 3107 C CG2 . THR C 3 232 ? 401.581 344.884 474.699 1.00 45.99  ? 232 THR A CG2 1 
ATOM 3108 N N   . VAL C 3 233 ? 398.358 342.812 473.620 1.00 42.13  ? 233 VAL A N   1 
ATOM 3109 C CA  . VAL C 3 233 ? 397.655 342.686 472.350 1.00 42.13  ? 233 VAL A CA  1 
ATOM 3110 C C   . VAL C 3 233 ? 396.665 343.835 472.215 1.00 42.13  ? 233 VAL A C   1 
ATOM 3111 O O   . VAL C 3 233 ? 395.910 344.136 473.141 1.00 42.13  ? 233 VAL A O   1 
ATOM 3112 C CB  . VAL C 3 233 ? 396.982 341.300 472.232 1.00 42.13  ? 233 VAL A CB  1 
ATOM 3113 C CG1 . VAL C 3 233 ? 396.264 340.942 473.505 1.00 42.13  ? 233 VAL A CG1 1 
ATOM 3114 C CG2 . VAL C 3 233 ? 396.025 341.249 471.064 1.00 42.13  ? 233 VAL A CG2 1 
ATOM 3115 N N   . ARG C 3 234 ? 396.699 344.504 471.067 1.00 43.06  ? 234 ARG A N   1 
ATOM 3116 C CA  . ARG C 3 234 ? 395.783 345.590 470.754 1.00 43.06  ? 234 ARG A CA  1 
ATOM 3117 C C   . ARG C 3 234 ? 394.937 345.164 469.569 1.00 43.06  ? 234 ARG A C   1 
ATOM 3118 O O   . ARG C 3 234 ? 395.473 344.722 468.551 1.00 43.06  ? 234 ARG A O   1 
ATOM 3119 C CB  . ARG C 3 234 ? 396.542 346.876 470.438 1.00 43.06  ? 234 ARG A CB  1 
ATOM 3120 C CG  . ARG C 3 234 ? 397.577 347.251 471.467 1.00 43.06  ? 234 ARG A CG  1 
ATOM 3121 C CD  . ARG C 3 234 ? 398.829 347.783 470.809 1.00 43.06  ? 234 ARG A CD  1 
ATOM 3122 N NE  . ARG C 3 234 ? 399.803 348.223 471.796 1.00 43.06  ? 234 ARG A NE  1 
ATOM 3123 C CZ  . ARG C 3 234 ? 400.059 349.496 472.062 1.00 43.06  ? 234 ARG A CZ  1 
ATOM 3124 N NH1 . ARG C 3 234 ? 399.417 350.449 471.405 1.00 43.06  ? 234 ARG A NH1 1 
ATOM 3125 N NH2 . ARG C 3 234 ? 400.958 349.818 472.980 1.00 43.06  ? 234 ARG A NH2 1 
ATOM 3126 N N   . ILE C 3 235 ? 393.627 345.295 469.698 1.00 40.51  ? 235 ILE A N   1 
ATOM 3127 C CA  . ILE C 3 235 ? 392.685 344.794 468.709 1.00 40.51  ? 235 ILE A CA  1 
ATOM 3128 C C   . ILE C 3 235 ? 392.127 345.969 467.927 1.00 40.51  ? 235 ILE A C   1 
ATOM 3129 O O   . ILE C 3 235 ? 391.628 346.932 468.518 1.00 40.51  ? 235 ILE A O   1 
ATOM 3130 C CB  . ILE C 3 235 ? 391.559 343.997 469.382 1.00 40.51  ? 235 ILE A CB  1 
ATOM 3131 C CG1 . ILE C 3 235 ? 392.145 342.859 470.200 1.00 40.51  ? 235 ILE A CG1 1 
ATOM 3132 C CG2 . ILE C 3 235 ? 390.624 343.450 468.361 1.00 40.51  ? 235 ILE A CG2 1 
ATOM 3133 C CD1 . ILE C 3 235 ? 391.125 342.083 470.947 1.00 40.51  ? 235 ILE A CD1 1 
ATOM 3134 N N   . TYR C 3 236 ? 392.203 345.898 466.603 1.00 40.23  ? 236 TYR A N   1 
ATOM 3135 C CA  . TYR C 3 236 ? 391.692 346.948 465.737 1.00 40.23  ? 236 TYR A CA  1 
ATOM 3136 C C   . TYR C 3 236 ? 390.415 346.476 465.062 1.00 40.23  ? 236 TYR A C   1 
ATOM 3137 O O   . TYR C 3 236 ? 390.290 345.308 464.699 1.00 40.23  ? 236 TYR A O   1 
ATOM 3138 C CB  . TYR C 3 236 ? 392.744 347.366 464.714 1.00 40.23  ? 236 TYR A CB  1 
ATOM 3139 C CG  . TYR C 3 236 ? 393.802 348.226 465.348 1.00 40.23  ? 236 TYR A CG  1 
ATOM 3140 C CD1 . TYR C 3 236 ? 393.621 349.590 465.479 1.00 40.23  ? 236 TYR A CD1 1 
ATOM 3141 C CD2 . TYR C 3 236 ? 394.955 347.668 465.862 1.00 40.23  ? 236 TYR A CD2 1 
ATOM 3142 C CE1 . TYR C 3 236 ? 394.566 350.377 466.082 1.00 40.23  ? 236 TYR A CE1 1 
ATOM 3143 C CE2 . TYR C 3 236 ? 395.906 348.448 466.468 1.00 40.23  ? 236 TYR A CE2 1 
ATOM 3144 C CZ  . TYR C 3 236 ? 395.703 349.802 466.574 1.00 40.23  ? 236 TYR A CZ  1 
ATOM 3145 O OH  . TYR C 3 236 ? 396.648 350.592 467.174 1.00 40.23  ? 236 TYR A OH  1 
ATOM 3146 N N   . PHE C 3 237 ? 389.472 347.392 464.897 1.00 45.55  ? 237 PHE A N   1 
ATOM 3147 C CA  . PHE C 3 237 ? 388.072 347.075 464.662 1.00 45.55  ? 237 PHE A CA  1 
ATOM 3148 C C   . PHE C 3 237 ? 387.596 347.834 463.438 1.00 45.55  ? 237 PHE A C   1 
ATOM 3149 O O   . PHE C 3 237 ? 387.683 349.063 463.400 1.00 45.55  ? 237 PHE A O   1 
ATOM 3150 C CB  . PHE C 3 237 ? 387.263 347.482 465.890 1.00 45.55  ? 237 PHE A CB  1 
ATOM 3151 C CG  . PHE C 3 237 ? 385.827 347.068 465.871 1.00 45.55  ? 237 PHE A CG  1 
ATOM 3152 C CD1 . PHE C 3 237 ? 385.447 345.854 466.406 1.00 45.55  ? 237 PHE A CD1 1 
ATOM 3153 C CD2 . PHE C 3 237 ? 384.846 347.921 465.389 1.00 45.55  ? 237 PHE A CD2 1 
ATOM 3154 C CE1 . PHE C 3 237 ? 384.128 345.486 466.432 1.00 45.55  ? 237 PHE A CE1 1 
ATOM 3155 C CE2 . PHE C 3 237 ? 383.525 347.551 465.400 1.00 45.55  ? 237 PHE A CE2 1 
ATOM 3156 C CZ  . PHE C 3 237 ? 383.168 346.334 465.924 1.00 45.55  ? 237 PHE A CZ  1 
ATOM 3157 N N   . LYS C 3 238 ? 387.067 347.123 462.462 1.00 47.27  ? 238 LYS A N   1 
ATOM 3158 C CA  . LYS C 3 238 ? 386.710 347.814 461.234 1.00 47.27  ? 238 LYS A CA  1 
ATOM 3159 C C   . LYS C 3 238 ? 385.424 347.255 460.646 1.00 47.27  ? 238 LYS A C   1 
ATOM 3160 O O   . LYS C 3 238 ? 385.376 346.080 460.269 1.00 47.27  ? 238 LYS A O   1 
ATOM 3161 C CB  . LYS C 3 238 ? 387.857 347.701 460.237 1.00 47.27  ? 238 LYS A CB  1 
ATOM 3162 C CG  . LYS C 3 238 ? 387.615 348.323 458.891 1.00 47.27  ? 238 LYS A CG  1 
ATOM 3163 C CD  . LYS C 3 238 ? 388.945 348.656 458.256 1.00 47.27  ? 238 LYS A CD  1 
ATOM 3164 C CE  . LYS C 3 238 ? 388.814 348.974 456.795 1.00 47.27  ? 238 LYS A CE  1 
ATOM 3165 N NZ  . LYS C 3 238 ? 388.845 347.739 455.977 1.00 47.27  ? 238 LYS A NZ  1 
ATOM 3166 N N   . PRO C 3 239 ? 384.362 348.050 460.569 1.00 47.22  ? 239 PRO A N   1 
ATOM 3167 C CA  . PRO C 3 239 ? 383.154 347.590 459.887 1.00 47.22  ? 239 PRO A CA  1 
ATOM 3168 C C   . PRO C 3 239 ? 383.378 347.529 458.391 1.00 47.22  ? 239 PRO A C   1 
ATOM 3169 O O   . PRO C 3 239 ? 384.239 348.215 457.844 1.00 47.22  ? 239 PRO A O   1 
ATOM 3170 C CB  . PRO C 3 239 ? 382.116 348.658 460.247 1.00 47.22  ? 239 PRO A CB  1 
ATOM 3171 C CG  . PRO C 3 239 ? 382.701 349.410 461.378 1.00 47.22  ? 239 PRO A CG  1 
ATOM 3172 C CD  . PRO C 3 239 ? 384.166 349.369 461.180 1.00 47.22  ? 239 PRO A CD  1 
ATOM 3173 N N   . LYS C 3 240 ? 382.598 346.693 457.725 1.00 49.06  ? 240 LYS A N   1 
ATOM 3174 C CA  . LYS C 3 240 ? 382.719 346.553 456.286 1.00 49.06  ? 240 LYS A CA  1 
ATOM 3175 C C   . LYS C 3 240 ? 381.345 346.336 455.683 1.00 49.06  ? 240 LYS A C   1 
ATOM 3176 O O   . LYS C 3 240 ? 380.556 345.552 456.213 1.00 49.06  ? 240 LYS A O   1 
ATOM 3177 C CB  . LYS C 3 240 ? 383.633 345.388 455.913 1.00 49.06  ? 240 LYS A CB  1 
ATOM 3178 C CG  . LYS C 3 240 ? 385.107 345.715 455.875 1.00 49.06  ? 240 LYS A CG  1 
ATOM 3179 C CD  . LYS C 3 240 ? 385.872 344.612 455.190 1.00 49.06  ? 240 LYS A CD  1 
ATOM 3180 C CE  . LYS C 3 240 ? 385.636 343.276 455.875 1.00 49.06  ? 240 LYS A CE  1 
ATOM 3181 N NZ  . LYS C 3 240 ? 385.885 342.127 454.966 1.00 49.06  ? 240 LYS A NZ  1 
ATOM 3182 N N   . HIS C 3 241 ? 381.089 347.025 454.567 1.00 50.27  ? 241 HIS A N   1 
ATOM 3183 C CA  . HIS C 3 241 ? 379.829 346.977 453.825 1.00 50.27  ? 241 HIS A CA  1 
ATOM 3184 C C   . HIS C 3 241 ? 378.647 347.326 454.728 1.00 50.27  ? 241 HIS A C   1 
ATOM 3185 O O   . HIS C 3 241 ? 377.770 346.510 455.000 1.00 50.27  ? 241 HIS A O   1 
ATOM 3186 C CB  . HIS C 3 241 ? 379.641 345.619 453.147 1.00 50.27  ? 241 HIS A CB  1 
ATOM 3187 C CG  . HIS C 3 241 ? 380.879 345.102 452.488 1.00 50.27  ? 241 HIS A CG  1 
ATOM 3188 N ND1 . HIS C 3 241 ? 381.638 344.088 453.027 1.00 50.27  ? 241 HIS A ND1 1 
ATOM 3189 C CD2 . HIS C 3 241 ? 381.493 345.462 451.338 1.00 50.27  ? 241 HIS A CD2 1 
ATOM 3190 C CE1 . HIS C 3 241 ? 382.666 343.844 452.236 1.00 50.27  ? 241 HIS A CE1 1 
ATOM 3191 N NE2 . HIS C 3 241 ? 382.602 344.665 451.204 1.00 50.27  ? 241 HIS A NE2 1 
ATOM 3192 N N   . VAL C 3 242 ? 378.658 348.554 455.198 1.00 47.32  ? 242 VAL A N   1 
ATOM 3193 C CA  . VAL C 3 242 ? 377.751 349.005 456.242 1.00 47.32  ? 242 VAL A CA  1 
ATOM 3194 C C   . VAL C 3 242 ? 376.410 349.343 455.617 1.00 47.32  ? 242 VAL A C   1 
ATOM 3195 O O   . VAL C 3 242 ? 376.346 349.971 454.557 1.00 47.32  ? 242 VAL A O   1 
ATOM 3196 C CB  . VAL C 3 242 ? 378.348 350.219 456.976 1.00 47.32  ? 242 VAL A CB  1 
ATOM 3197 C CG1 . VAL C 3 242 ? 377.469 350.646 458.113 1.00 47.32  ? 242 VAL A CG1 1 
ATOM 3198 C CG2 . VAL C 3 242 ? 379.728 349.905 457.477 1.00 47.32  ? 242 VAL A CG2 1 
ATOM 3199 N N   . LYS C 3 243 ? 375.335 348.906 456.263 1.00 48.98  ? 243 LYS A N   1 
ATOM 3200 C CA  . LYS C 3 243 ? 373.989 349.362 455.957 1.00 48.98  ? 243 LYS A CA  1 
ATOM 3201 C C   . LYS C 3 243 ? 373.398 349.937 457.231 1.00 48.98  ? 243 LYS A C   1 
ATOM 3202 O O   . LYS C 3 243 ? 373.593 349.375 458.310 1.00 48.98  ? 243 LYS A O   1 
ATOM 3203 C CB  . LYS C 3 243 ? 373.126 348.225 455.425 1.00 48.98  ? 243 LYS A CB  1 
ATOM 3204 C CG  . LYS C 3 243 ? 373.348 347.949 453.962 1.00 48.98  ? 243 LYS A CG  1 
ATOM 3205 C CD  . LYS C 3 243 ? 373.220 346.481 453.648 1.00 48.98  ? 243 LYS A CD  1 
ATOM 3206 C CE  . LYS C 3 243 ? 373.656 346.203 452.229 1.00 48.98  ? 243 LYS A CE  1 
ATOM 3207 N NZ  . LYS C 3 243 ? 372.556 346.423 451.261 1.00 48.98  ? 243 LYS A NZ  1 
ATOM 3208 N N   . ALA C 3 244 ? 372.699 351.058 457.116 1.00 48.24  ? 244 ALA A N   1 
ATOM 3209 C CA  . ALA C 3 244 ? 372.153 351.734 458.280 1.00 48.24  ? 244 ALA A CA  1 
ATOM 3210 C C   . ALA C 3 244 ? 370.710 352.130 458.028 1.00 48.24  ? 244 ALA A C   1 
ATOM 3211 O O   . ALA C 3 244 ? 370.373 352.613 456.946 1.00 48.24  ? 244 ALA A O   1 
ATOM 3212 C CB  . ALA C 3 244 ? 372.971 352.967 458.630 1.00 48.24  ? 244 ALA A CB  1 
ATOM 3213 N N   . TRP C 3 245 ? 369.865 351.936 459.034 1.00 47.68  ? 245 TRP A N   1 
ATOM 3214 C CA  . TRP C 3 245 ? 368.456 352.273 458.952 1.00 47.68  ? 245 TRP A CA  1 
ATOM 3215 C C   . TRP C 3 245 ? 368.059 353.121 460.151 1.00 47.68  ? 245 TRP A C   1 
ATOM 3216 O O   . TRP C 3 245 ? 368.655 353.014 461.223 1.00 47.68  ? 245 TRP A O   1 
ATOM 3217 C CB  . TRP C 3 245 ? 367.577 351.024 458.920 1.00 47.68  ? 245 TRP A CB  1 
ATOM 3218 C CG  . TRP C 3 245 ? 367.709 350.186 457.709 1.00 47.68  ? 245 TRP A CG  1 
ATOM 3219 C CD1 . TRP C 3 245 ? 367.025 350.321 456.549 1.00 47.68  ? 245 TRP A CD1 1 
ATOM 3220 C CD2 . TRP C 3 245 ? 368.555 349.051 457.547 1.00 47.68  ? 245 TRP A CD2 1 
ATOM 3221 N NE1 . TRP C 3 245 ? 367.401 349.352 455.662 1.00 47.68  ? 245 TRP A NE1 1 
ATOM 3222 C CE2 . TRP C 3 245 ? 368.342 348.556 456.254 1.00 47.68  ? 245 TRP A CE2 1 
ATOM 3223 C CE3 . TRP C 3 245 ? 369.479 348.410 458.368 1.00 47.68  ? 245 TRP A CE3 1 
ATOM 3224 C CZ2 . TRP C 3 245 ? 369.019 347.452 455.763 1.00 47.68  ? 245 TRP A CZ2 1 
ATOM 3225 C CZ3 . TRP C 3 245 ? 370.146 347.320 457.880 1.00 47.68  ? 245 TRP A CZ3 1 
ATOM 3226 C CH2 . TRP C 3 245 ? 369.916 346.850 456.591 1.00 47.68  ? 245 TRP A CH2 1 
ATOM 3227 N N   . VAL C 3 246 ? 367.007 353.919 459.954 1.00 47.08  ? 246 VAL A N   1 
ATOM 3228 C CA  . VAL C 3 246 ? 366.303 354.700 460.977 1.00 47.08  ? 246 VAL A CA  1 
ATOM 3229 C C   . VAL C 3 246 ? 367.259 355.624 461.726 1.00 47.08  ? 246 VAL A C   1 
ATOM 3230 O O   . VAL C 3 246 ? 367.789 355.243 462.779 1.00 47.08  ? 246 VAL A O   1 
ATOM 3231 C CB  . VAL C 3 246 ? 365.528 353.782 461.938 1.00 47.08  ? 246 VAL A CB  1 
ATOM 3232 C CG1 . VAL C 3 246 ? 364.672 354.586 462.904 1.00 47.08  ? 246 VAL A CG1 1 
ATOM 3233 C CG2 . VAL C 3 246 ? 364.651 352.841 461.154 1.00 47.08  ? 246 VAL A CG2 1 
ATOM 3234 N N   . PRO C 3 247 ? 367.600 356.784 461.164 1.00 45.35  ? 247 PRO A N   1 
ATOM 3235 C CA  . PRO C 3 247 ? 368.494 357.715 461.861 1.00 45.35  ? 247 PRO A CA  1 
ATOM 3236 C C   . PRO C 3 247 ? 367.882 358.254 463.146 1.00 45.35  ? 247 PRO A C   1 
ATOM 3237 O O   . PRO C 3 247 ? 366.678 358.171 463.380 1.00 45.35  ? 247 PRO A O   1 
ATOM 3238 C CB  . PRO C 3 247 ? 368.715 358.830 460.838 1.00 45.35  ? 247 PRO A CB  1 
ATOM 3239 C CG  . PRO C 3 247 ? 367.545 358.762 459.955 1.00 45.35  ? 247 PRO A CG  1 
ATOM 3240 C CD  . PRO C 3 247 ? 367.122 357.334 459.888 1.00 45.35  ? 247 PRO A CD  1 
ATOM 3241 N N   . ARG C 3 248 ? 368.743 358.833 463.978 1.00 45.69  ? 248 ARG A N   1 
ATOM 3242 C CA  . ARG C 3 248 ? 368.493 359.056 465.388 1.00 45.69  ? 248 ARG A CA  1 
ATOM 3243 C C   . ARG C 3 248 ? 369.330 360.266 465.777 1.00 45.69  ? 248 ARG A C   1 
ATOM 3244 O O   . ARG C 3 248 ? 370.371 360.492 465.148 1.00 45.69  ? 248 ARG A O   1 
ATOM 3245 C CB  . ARG C 3 248 ? 368.907 357.803 466.168 1.00 45.69  ? 248 ARG A CB  1 
ATOM 3246 C CG  . ARG C 3 248 ? 368.499 357.694 467.609 1.00 45.69  ? 248 ARG A CG  1 
ATOM 3247 C CD  . ARG C 3 248 ? 368.601 356.274 468.077 1.00 45.69  ? 248 ARG A CD  1 
ATOM 3248 N NE  . ARG C 3 248 ? 367.306 355.614 468.070 1.00 45.69  ? 248 ARG A NE  1 
ATOM 3249 C CZ  . ARG C 3 248 ? 366.472 355.616 469.101 1.00 45.69  ? 248 ARG A CZ  1 
ATOM 3250 N NH1 . ARG C 3 248 ? 366.798 356.244 470.218 1.00 45.69  ? 248 ARG A NH1 1 
ATOM 3251 N NH2 . ARG C 3 248 ? 365.314 354.987 469.018 1.00 45.69  ? 248 ARG A NH2 1 
ATOM 3252 N N   . PRO C 3 249 ? 368.905 361.082 466.750 1.00 42.93  ? 249 PRO A N   1 
ATOM 3253 C CA  . PRO C 3 249 ? 369.687 362.267 467.090 1.00 42.93  ? 249 PRO A CA  1 
ATOM 3254 C C   . PRO C 3 249 ? 370.981 361.889 467.787 1.00 42.93  ? 249 PRO A C   1 
ATOM 3255 O O   . PRO C 3 249 ? 371.082 360.810 468.393 1.00 42.93  ? 249 PRO A O   1 
ATOM 3256 C CB  . PRO C 3 249 ? 368.755 363.047 468.032 1.00 42.93  ? 249 PRO A CB  1 
ATOM 3257 C CG  . PRO C 3 249 ? 367.454 362.529 467.806 1.00 42.93  ? 249 PRO A CG  1 
ATOM 3258 C CD  . PRO C 3 249 ? 367.587 361.126 467.393 1.00 42.93  ? 249 PRO A CD  1 
ATOM 3259 N N   . PRO C 3 250 ? 372.004 362.737 467.715 1.00 44.61  ? 250 PRO A N   1 
ATOM 3260 C CA  . PRO C 3 250 ? 373.276 362.402 468.355 1.00 44.61  ? 250 PRO A CA  1 
ATOM 3261 C C   . PRO C 3 250 ? 373.238 362.700 469.841 1.00 44.61  ? 250 PRO A C   1 
ATOM 3262 O O   . PRO C 3 250 ? 372.555 363.621 470.291 1.00 44.61  ? 250 PRO A O   1 
ATOM 3263 C CB  . PRO C 3 250 ? 374.286 363.306 467.639 1.00 44.61  ? 250 PRO A CB  1 
ATOM 3264 C CG  . PRO C 3 250 ? 373.530 363.994 466.561 1.00 44.61  ? 250 PRO A CG  1 
ATOM 3265 C CD  . PRO C 3 250 ? 372.109 363.992 466.964 1.00 44.61  ? 250 PRO A CD  1 
ATOM 3266 N N   . ARG C 3 251 ? 374.003 361.912 470.591 1.00 49.08  ? 251 ARG A N   1 
ATOM 3267 C CA  . ARG C 3 251 ? 374.017 361.973 472.046 1.00 49.08  ? 251 ARG A CA  1 
ATOM 3268 C C   . ARG C 3 251 ? 374.561 363.313 472.530 1.00 49.08  ? 251 ARG A C   1 
ATOM 3269 O O   . ARG C 3 251 ? 375.497 363.860 471.946 1.00 49.08  ? 251 ARG A O   1 
ATOM 3270 C CB  . ARG C 3 251 ? 374.859 360.816 472.578 1.00 49.08  ? 251 ARG A CB  1 
ATOM 3271 C CG  . ARG C 3 251 ? 375.080 360.784 474.064 1.00 49.08  ? 251 ARG A CG  1 
ATOM 3272 C CD  . ARG C 3 251 ? 374.061 359.925 474.756 1.00 49.08  ? 251 ARG A CD  1 
ATOM 3273 N NE  . ARG C 3 251 ? 374.388 359.723 476.158 1.00 49.08  ? 251 ARG A NE  1 
ATOM 3274 C CZ  . ARG C 3 251 ? 373.726 358.900 476.956 1.00 49.08  ? 251 ARG A CZ  1 
ATOM 3275 N NH1 . ARG C 3 251 ? 372.709 358.210 476.483 1.00 49.08  ? 251 ARG A NH1 1 
ATOM 3276 N NH2 . ARG C 3 251 ? 374.079 358.765 478.221 1.00 49.08  ? 251 ARG A NH2 1 
ATOM 3277 N N   . LEU C 3 252 ? 373.954 363.854 473.584 1.00 50.13  ? 252 LEU A N   1 
ATOM 3278 C CA  . LEU C 3 252 ? 374.355 365.136 474.146 1.00 50.13  ? 252 LEU A CA  1 
ATOM 3279 C C   . LEU C 3 252 ? 375.058 364.981 475.487 1.00 50.13  ? 252 LEU A C   1 
ATOM 3280 O O   . LEU C 3 252 ? 376.122 365.565 475.702 1.00 50.13  ? 252 LEU A O   1 
ATOM 3281 C CB  . LEU C 3 252 ? 373.131 366.034 474.296 1.00 50.13  ? 252 LEU A CB  1 
ATOM 3282 C CG  . LEU C 3 252 ? 373.271 367.334 475.073 1.00 50.13  ? 252 LEU A CG  1 
ATOM 3283 C CD1 . LEU C 3 252 ? 373.768 368.407 474.158 1.00 50.13  ? 252 LEU A CD1 1 
ATOM 3284 C CD2 . LEU C 3 252 ? 371.933 367.719 475.648 1.00 50.13  ? 252 LEU A CD2 1 
ATOM 3285 N N   . CYS C 3 253 ? 374.481 364.209 476.399 1.00 54.16  ? 253 CYS A N   1 
ATOM 3286 C CA  . CYS C 3 253 ? 375.109 363.981 477.688 1.00 54.16  ? 253 CYS A CA  1 
ATOM 3287 C C   . CYS C 3 253 ? 376.283 363.019 477.548 1.00 54.16  ? 253 CYS A C   1 
ATOM 3288 O O   . CYS C 3 253 ? 376.489 362.394 476.509 1.00 54.16  ? 253 CYS A O   1 
ATOM 3289 C CB  . CYS C 3 253 ? 374.104 363.416 478.687 1.00 54.16  ? 253 CYS A CB  1 
ATOM 3290 S SG  . CYS C 3 253 ? 372.471 364.157 478.617 1.00 54.16  ? 253 CYS A SG  1 
ATOM 3291 N N   . GLN C 3 254 ? 377.056 362.897 478.616 1.00 54.33  ? 254 GLN A N   1 
ATOM 3292 C CA  . GLN C 3 254 ? 378.192 361.995 478.595 1.00 54.33  ? 254 GLN A CA  1 
ATOM 3293 C C   . GLN C 3 254 ? 377.735 360.569 478.842 1.00 54.33  ? 254 GLN A C   1 
ATOM 3294 O O   . GLN C 3 254 ? 376.716 360.325 479.487 1.00 54.33  ? 254 GLN A O   1 
ATOM 3295 C CB  . GLN C 3 254 ? 379.222 362.399 479.645 1.00 54.33  ? 254 GLN A CB  1 
ATOM 3296 C CG  . GLN C 3 254 ? 379.839 363.752 479.407 1.00 54.33  ? 254 GLN A CG  1 
ATOM 3297 C CD  . GLN C 3 254 ? 380.810 363.731 478.257 1.00 54.33  ? 254 GLN A CD  1 
ATOM 3298 O OE1 . GLN C 3 254 ? 381.370 362.689 477.929 1.00 54.33  ? 254 GLN A OE1 1 
ATOM 3299 N NE2 . GLN C 3 254 ? 381.016 364.880 477.631 1.00 54.33  ? 254 GLN A NE2 1 
ATOM 3300 N N   . TYR C 3 255 ? 378.496 359.621 478.314 1.00 52.17  ? 255 TYR A N   1 
ATOM 3301 C CA  . TYR C 3 255 ? 378.217 358.219 478.558 1.00 52.17  ? 255 TYR A CA  1 
ATOM 3302 C C   . TYR C 3 255 ? 378.668 357.847 479.958 1.00 52.17  ? 255 TYR A C   1 
ATOM 3303 O O   . TYR C 3 255 ? 379.738 358.258 480.411 1.00 52.17  ? 255 TYR A O   1 
ATOM 3304 C CB  . TYR C 3 255 ? 378.930 357.344 477.539 1.00 52.17  ? 255 TYR A CB  1 
ATOM 3305 C CG  . TYR C 3 255 ? 378.297 357.343 476.186 1.00 52.17  ? 255 TYR A CG  1 
ATOM 3306 C CD1 . TYR C 3 255 ? 377.042 356.807 475.997 1.00 52.17  ? 255 TYR A CD1 1 
ATOM 3307 C CD2 . TYR C 3 255 ? 378.957 357.873 475.093 1.00 52.17  ? 255 TYR A CD2 1 
ATOM 3308 C CE1 . TYR C 3 255 ? 376.457 356.801 474.756 1.00 52.17  ? 255 TYR A CE1 1 
ATOM 3309 C CE2 . TYR C 3 255 ? 378.381 357.872 473.850 1.00 52.17  ? 255 TYR A CE2 1 
ATOM 3310 C CZ  . TYR C 3 255 ? 377.131 357.334 473.690 1.00 52.17  ? 255 TYR A CZ  1 
ATOM 3311 O OH  . TYR C 3 255 ? 376.540 357.325 472.454 1.00 52.17  ? 255 TYR A OH  1 
ATOM 3312 N N   . GLU C 3 256 ? 377.851 357.060 480.644 1.00 57.68  ? 256 GLU A N   1 
ATOM 3313 C CA  . GLU C 3 256 ? 378.139 356.667 482.012 1.00 57.68  ? 256 GLU A CA  1 
ATOM 3314 C C   . GLU C 3 256 ? 378.440 355.180 482.120 1.00 57.68  ? 256 GLU A C   1 
ATOM 3315 O O   . GLU C 3 256 ? 379.481 354.797 482.658 1.00 57.68  ? 256 GLU A O   1 
ATOM 3316 C CB  . GLU C 3 256 ? 376.970 357.052 482.921 1.00 57.68  ? 256 GLU A CB  1 
ATOM 3317 C CG  . GLU C 3 256 ? 376.571 358.513 482.823 1.00 57.68  ? 256 GLU A CG  1 
ATOM 3318 C CD  . GLU C 3 256 ? 377.584 359.451 483.449 1.00 57.68  ? 256 GLU A CD  1 
ATOM 3319 O OE1 . GLU C 3 256 ? 377.687 360.606 482.992 1.00 57.68  ? 256 GLU A OE1 1 
ATOM 3320 O OE2 . GLU C 3 256 ? 378.277 359.041 484.400 1.00 57.68  ? 256 GLU A OE2 1 
ATOM 3321 N N   . LYS C 3 257 ? 377.560 354.329 481.619 1.00 57.31  ? 257 LYS A N   1 
ATOM 3322 C CA  . LYS C 3 257 ? 377.772 352.897 481.684 1.00 57.31  ? 257 LYS A CA  1 
ATOM 3323 C C   . LYS C 3 257 ? 377.810 352.320 480.281 1.00 57.31  ? 257 LYS A C   1 
ATOM 3324 O O   . LYS C 3 257 ? 377.567 353.009 479.289 1.00 57.31  ? 257 LYS A O   1 
ATOM 3325 C CB  . LYS C 3 257 ? 376.683 352.206 482.502 1.00 57.31  ? 257 LYS A CB  1 
ATOM 3326 C CG  . LYS C 3 257 ? 376.792 352.388 483.992 1.00 57.31  ? 257 LYS A CG  1 
ATOM 3327 C CD  . LYS C 3 257 ? 378.064 351.765 484.514 1.00 57.31  ? 257 LYS A CD  1 
ATOM 3328 C CE  . LYS C 3 257 ? 378.093 351.785 486.021 1.00 57.31  ? 257 LYS A CE  1 
ATOM 3329 N NZ  . LYS C 3 257 ? 376.932 351.036 486.542 1.00 57.31  ? 257 LYS A NZ  1 
ATOM 3330 N N   . GLN C 3 258 ? 378.111 351.029 480.215 1.00 55.47  ? 258 GLN A N   1 
ATOM 3331 C CA  . GLN C 3 258 ? 378.274 350.336 478.949 1.00 55.47  ? 258 GLN A CA  1 
ATOM 3332 C C   . GLN C 3 258 ? 376.980 349.692 478.475 1.00 55.47  ? 258 GLN A C   1 
ATOM 3333 O O   . GLN C 3 258 ? 376.588 349.861 477.318 1.00 55.47  ? 258 GLN A O   1 
ATOM 3334 C CB  . GLN C 3 258 ? 379.363 349.282 479.084 1.00 55.47  ? 258 GLN A CB  1 
ATOM 3335 C CG  . GLN C 3 258 ? 379.431 348.318 477.944 1.00 55.47  ? 258 GLN A CG  1 
ATOM 3336 C CD  . GLN C 3 258 ? 380.260 347.113 478.292 1.00 55.47  ? 258 GLN A CD  1 
ATOM 3337 O OE1 . GLN C 3 258 ? 380.625 346.908 479.446 1.00 55.47  ? 258 GLN A OE1 1 
ATOM 3338 N NE2 . GLN C 3 258 ? 380.569 346.313 477.302 1.00 55.47  ? 258 GLN A NE2 1 
ATOM 3339 N N   . LYS C 3 259 ? 376.306 348.959 479.359 1.00 53.52  ? 259 LYS A N   1 
ATOM 3340 C CA  . LYS C 3 259 ? 375.183 348.134 478.933 1.00 53.52  ? 259 LYS A CA  1 
ATOM 3341 C C   . LYS C 3 259 ? 373.940 348.959 478.632 1.00 53.52  ? 259 LYS A C   1 
ATOM 3342 O O   . LYS C 3 259 ? 373.248 348.696 477.644 1.00 53.52  ? 259 LYS A O   1 
ATOM 3343 C CB  . LYS C 3 259 ? 374.880 347.083 479.996 1.00 53.52  ? 259 LYS A CB  1 
ATOM 3344 C CG  . LYS C 3 259 ? 375.946 346.007 480.121 1.00 53.52  ? 259 LYS A CG  1 
ATOM 3345 C CD  . LYS C 3 259 ? 376.238 345.355 478.779 1.00 53.52  ? 259 LYS A CD  1 
ATOM 3346 C CE  . LYS C 3 259 ? 376.221 343.844 478.878 1.00 53.52  ? 259 LYS A CE  1 
ATOM 3347 N NZ  . LYS C 3 259 ? 377.041 343.358 480.009 1.00 53.52  ? 259 LYS A NZ  1 
ATOM 3348 N N   . ASN C 3 260 ? 373.645 349.959 479.451 1.00 54.68  ? 260 ASN A N   1 
ATOM 3349 C CA  . ASN C 3 260 ? 372.403 350.708 479.350 1.00 54.68  ? 260 ASN A CA  1 
ATOM 3350 C C   . ASN C 3 260 ? 372.673 352.125 478.859 1.00 54.68  ? 260 ASN A C   1 
ATOM 3351 O O   . ASN C 3 260 ? 373.787 352.476 478.472 1.00 54.68  ? 260 ASN A O   1 
ATOM 3352 C CB  . ASN C 3 260 ? 371.675 350.701 480.691 1.00 54.68  ? 260 ASN A CB  1 
ATOM 3353 C CG  . ASN C 3 260 ? 372.603 350.932 481.850 1.00 54.68  ? 260 ASN A CG  1 
ATOM 3354 O OD1 . ASN C 3 260 ? 373.653 351.532 481.698 1.00 54.68  ? 260 ASN A OD1 1 
ATOM 3355 N ND2 . ASN C 3 260 ? 372.230 350.434 483.017 1.00 54.68  ? 260 ASN A ND2 1 
ATOM 3356 N N   . VAL C 3 261 ? 371.630 352.945 478.883 1.00 51.71  ? 261 VAL A N   1 
ATOM 3357 C CA  . VAL C 3 261 ? 371.657 354.256 478.249 1.00 51.71  ? 261 VAL A CA  1 
ATOM 3358 C C   . VAL C 3 261 ? 371.490 355.333 479.322 1.00 51.71  ? 261 VAL A C   1 
ATOM 3359 O O   . VAL C 3 261 ? 371.103 356.473 479.039 1.00 51.71  ? 261 VAL A O   1 
ATOM 3360 C CB  . VAL C 3 261 ? 370.586 354.295 477.134 1.00 51.71  ? 261 VAL A CB  1 
ATOM 3361 C CG1 . VAL C 3 261 ? 369.157 354.366 477.684 1.00 51.71  ? 261 VAL A CG1 1 
ATOM 3362 C CG2 . VAL C 3 261 ? 370.880 355.350 476.066 1.00 51.71  ? 261 VAL A CG2 1 
ATOM 3363 N N   . ASN C 3 262 ? 371.848 354.992 480.558 1.00 52.41  ? 262 ASN A N   1 
ATOM 3364 C CA  . ASN C 3 262 ? 371.658 355.894 481.685 1.00 52.41  ? 262 ASN A CA  1 
ATOM 3365 C C   . ASN C 3 262 ? 372.573 357.106 481.587 1.00 52.41  ? 262 ASN A C   1 
ATOM 3366 O O   . ASN C 3 262 ? 373.624 357.069 480.946 1.00 52.41  ? 262 ASN A O   1 
ATOM 3367 C CB  . ASN C 3 262 ? 371.915 355.167 482.997 1.00 52.41  ? 262 ASN A CB  1 
ATOM 3368 C CG  . ASN C 3 262 ? 370.792 354.244 483.374 1.00 52.41  ? 262 ASN A CG  1 
ATOM 3369 O OD1 . ASN C 3 262 ? 369.677 354.376 482.883 1.00 52.41  ? 262 ASN A OD1 1 
ATOM 3370 N ND2 . ASN C 3 262 ? 371.075 353.303 484.258 1.00 52.41  ? 262 ASN A ND2 1 
ATOM 3371 N N   . PHE C 3 263 ? 372.151 358.195 482.219 1.00 52.26  ? 263 PHE A N   1 
ATOM 3372 C CA  . PHE C 3 263 ? 372.842 359.469 482.093 1.00 52.26  ? 263 PHE A CA  1 
ATOM 3373 C C   . PHE C 3 263 ? 372.551 360.307 483.324 1.00 52.26  ? 263 PHE A C   1 
ATOM 3374 O O   . PHE C 3 263 ? 371.811 359.899 484.220 1.00 52.26  ? 263 PHE A O   1 
ATOM 3375 C CB  . PHE C 3 263 ? 372.420 360.217 480.823 1.00 52.26  ? 263 PHE A CB  1 
ATOM 3376 C CG  . PHE C 3 263 ? 370.964 360.622 480.795 1.00 52.26  ? 263 PHE A CG  1 
ATOM 3377 C CD1 . PHE C 3 263 ? 369.991 359.735 480.375 1.00 52.26  ? 263 PHE A CD1 1 
ATOM 3378 C CD2 . PHE C 3 263 ? 370.575 361.900 481.154 1.00 52.26  ? 263 PHE A CD2 1 
ATOM 3379 C CE1 . PHE C 3 263 ? 368.670 360.106 480.346 1.00 52.26  ? 263 PHE A CE1 1 
ATOM 3380 C CE2 . PHE C 3 263 ? 369.250 362.268 481.127 1.00 52.26  ? 263 PHE A CE2 1 
ATOM 3381 C CZ  . PHE C 3 263 ? 368.302 361.373 480.722 1.00 52.26  ? 263 PHE A CZ  1 
ATOM 3382 N N   . SER C 3 264 ? 373.144 361.497 483.347 1.00 53.28  ? 264 SER A N   1 
ATOM 3383 C CA  . SER C 3 264 ? 372.792 362.560 484.264 1.00 53.28  ? 264 SER A CA  1 
ATOM 3384 C C   . SER C 3 264 ? 372.512 363.819 483.459 1.00 53.28  ? 264 SER A C   1 
ATOM 3385 O O   . SER C 3 264 ? 373.226 364.090 482.491 1.00 53.28  ? 264 SER A O   1 
ATOM 3386 C CB  . SER C 3 264 ? 373.910 362.832 485.272 1.00 53.28  ? 264 SER A CB  1 
ATOM 3387 O OG  . SER C 3 264 ? 375.120 363.125 484.608 1.00 53.28  ? 264 SER A OG  1 
ATOM 3388 N N   . PRO C 3 265 ? 371.487 364.591 483.815 1.00 54.52  ? 265 PRO A N   1 
ATOM 3389 C CA  . PRO C 3 265 ? 371.006 365.641 482.913 1.00 54.52  ? 265 PRO A CA  1 
ATOM 3390 C C   . PRO C 3 265 ? 371.963 366.813 482.817 1.00 54.52  ? 265 PRO A C   1 
ATOM 3391 O O   . PRO C 3 265 ? 372.631 367.182 483.783 1.00 54.52  ? 265 PRO A O   1 
ATOM 3392 C CB  . PRO C 3 265 ? 369.676 366.062 483.541 1.00 54.52  ? 265 PRO A CB  1 
ATOM 3393 C CG  . PRO C 3 265 ? 369.301 364.942 484.418 1.00 54.52  ? 265 PRO A CG  1 
ATOM 3394 C CD  . PRO C 3 265 ? 370.586 364.424 484.958 1.00 54.52  ? 265 PRO A CD  1 
ATOM 3395 N N   . ILE C 3 266 ? 372.016 367.396 481.625 1.00 52.81  ? 266 ILE A N   1 
ATOM 3396 C CA  . ILE C 3 266 ? 372.992 368.407 481.261 1.00 52.81  ? 266 ILE A CA  1 
ATOM 3397 C C   . ILE C 3 266 ? 372.255 369.519 480.525 1.00 52.81  ? 266 ILE A C   1 
ATOM 3398 O O   . ILE C 3 266 ? 371.108 369.359 480.104 1.00 52.81  ? 266 ILE A O   1 
ATOM 3399 C CB  . ILE C 3 266 ? 374.117 367.791 480.399 1.00 52.81  ? 266 ILE A CB  1 
ATOM 3400 C CG1 . ILE C 3 266 ? 375.430 368.552 480.533 1.00 52.81  ? 266 ILE A CG1 1 
ATOM 3401 C CG2 . ILE C 3 266 ? 373.695 367.680 478.958 1.00 52.81  ? 266 ILE A CG2 1 
ATOM 3402 C CD1 . ILE C 3 266 ? 376.569 367.889 479.809 1.00 52.81  ? 266 ILE A CD1 1 
ATOM 3403 N N   . GLY C 3 267 ? 372.910 370.668 480.404 1.00 55.44  ? 267 GLY A N   1 
ATOM 3404 C CA  . GLY C 3 267 ? 372.317 371.780 479.697 1.00 55.44  ? 267 GLY A CA  1 
ATOM 3405 C C   . GLY C 3 267 ? 372.243 371.541 478.204 1.00 55.44  ? 267 GLY A C   1 
ATOM 3406 O O   . GLY C 3 267 ? 372.885 370.654 477.650 1.00 55.44  ? 267 GLY A O   1 
ATOM 3407 N N   . VAL C 3 268 ? 371.433 372.362 477.542 1.00 54.98  ? 268 VAL A N   1 
ATOM 3408 C CA  . VAL C 3 268 ? 371.197 372.187 476.114 1.00 54.98  ? 268 VAL A CA  1 
ATOM 3409 C C   . VAL C 3 268 ? 372.421 372.617 475.313 1.00 54.98  ? 268 VAL A C   1 
ATOM 3410 O O   . VAL C 3 268 ? 372.825 371.944 474.359 1.00 54.98  ? 268 VAL A O   1 
ATOM 3411 C CB  . VAL C 3 268 ? 369.929 372.953 475.700 1.00 54.98  ? 268 VAL A CB  1 
ATOM 3412 C CG1 . VAL C 3 268 ? 369.822 373.090 474.204 1.00 54.98  ? 268 VAL A CG1 1 
ATOM 3413 C CG2 . VAL C 3 268 ? 368.713 372.243 476.230 1.00 54.98  ? 268 VAL A CG2 1 
ATOM 3414 N N   . THR C 3 269 ? 373.066 373.707 475.723 1.00 58.46  ? 269 THR A N   1 
ATOM 3415 C CA  . THR C 3 269 ? 374.200 374.247 474.988 1.00 58.46  ? 269 THR A CA  1 
ATOM 3416 C C   . THR C 3 269 ? 375.068 375.074 475.926 1.00 58.46  ? 269 THR A C   1 
ATOM 3417 O O   . THR C 3 269 ? 374.796 375.187 477.121 1.00 58.46  ? 269 THR A O   1 
ATOM 3418 C CB  . THR C 3 269 ? 373.720 375.097 473.819 1.00 58.46  ? 269 THR A CB  1 
ATOM 3419 O OG1 . THR C 3 269 ? 374.844 375.676 473.147 1.00 58.46  ? 269 THR A OG1 1 
ATOM 3420 C CG2 . THR C 3 269 ? 372.841 376.187 474.342 1.00 58.46  ? 269 THR A CG2 1 
ATOM 3421 N N   . THR C 3 270 ? 376.129 375.649 475.371 1.00 58.01  ? 270 THR A N   1 
ATOM 3422 C CA  . THR C 3 270 ? 376.912 376.628 476.109 1.00 58.01  ? 270 THR A CA  1 
ATOM 3423 C C   . THR C 3 270 ? 376.178 377.958 476.139 1.00 58.01  ? 270 THR A C   1 
ATOM 3424 O O   . THR C 3 270 ? 375.596 378.388 475.142 1.00 58.01  ? 270 THR A O   1 
ATOM 3425 C CB  . THR C 3 270 ? 378.288 376.813 475.478 1.00 58.01  ? 270 THR A CB  1 
ATOM 3426 O OG1 . THR C 3 270 ? 378.130 377.190 474.107 1.00 58.01  ? 270 THR A OG1 1 
ATOM 3427 C CG2 . THR C 3 270 ? 379.103 375.540 475.567 1.00 58.01  ? 270 THR A CG2 1 
ATOM 3428 N N   . SER C 3 271 ? 376.221 378.616 477.284 1.00 56.37  ? 271 SER A N   1 
ATOM 3429 C CA  . SER C 3 271 ? 375.411 379.790 477.542 1.00 56.37  ? 271 SER A CA  1 
ATOM 3430 C C   . SER C 3 271 ? 376.133 381.063 477.129 1.00 56.37  ? 271 SER A C   1 
ATOM 3431 O O   . SER C 3 271 ? 377.334 381.066 476.861 1.00 56.37  ? 271 SER A O   1 
ATOM 3432 C CB  . SER C 3 271 ? 375.063 379.857 479.020 1.00 56.37  ? 271 SER A CB  1 
ATOM 3433 O OG  . SER C 3 271 ? 376.240 379.790 479.799 1.00 56.37  ? 271 SER A OG  1 
ATOM 3434 N N   . ARG C 3 272 ? 375.375 382.157 477.084 1.00 54.61  ? 272 ARG A N   1 
ATOM 3435 C CA  . ARG C 3 272 ? 375.911 383.486 476.837 1.00 54.61  ? 272 ARG A CA  1 
ATOM 3436 C C   . ARG C 3 272 ? 375.200 384.483 477.742 1.00 54.61  ? 272 ARG A C   1 
ATOM 3437 O O   . ARG C 3 272 ? 374.344 384.119 478.552 1.00 54.61  ? 272 ARG A O   1 
ATOM 3438 C CB  . ARG C 3 272 ? 375.774 383.881 475.365 1.00 54.61  ? 272 ARG A CB  1 
ATOM 3439 C CG  . ARG C 3 272 ? 374.385 383.749 474.789 1.00 54.61  ? 272 ARG A CG  1 
ATOM 3440 C CD  . ARG C 3 272 ? 374.392 384.241 473.356 1.00 54.61  ? 272 ARG A CD  1 
ATOM 3441 N NE  . ARG C 3 272 ? 373.091 384.166 472.711 1.00 54.61  ? 272 ARG A NE  1 
ATOM 3442 C CZ  . ARG C 3 272 ? 372.769 384.863 471.631 1.00 54.61  ? 272 ARG A CZ  1 
ATOM 3443 N NH1 . ARG C 3 272 ? 373.655 385.683 471.095 1.00 54.61  ? 272 ARG A NH1 1 
ATOM 3444 N NH2 . ARG C 3 272 ? 371.569 384.749 471.090 1.00 54.61  ? 272 ARG A NH2 1 
ATOM 3445 N N   . THR C 3 273 ? 375.553 385.758 477.602 1.00 60.24  ? 273 THR A N   1 
ATOM 3446 C CA  . THR C 3 273 ? 375.108 386.767 478.554 1.00 60.24  ? 273 THR A CA  1 
ATOM 3447 C C   . THR C 3 273 ? 373.786 387.416 478.181 1.00 60.24  ? 273 THR A C   1 
ATOM 3448 O O   . THR C 3 273 ? 372.998 387.737 479.075 1.00 60.24  ? 273 THR A O   1 
ATOM 3449 C CB  . THR C 3 273 ? 376.159 387.867 478.695 1.00 60.24  ? 273 THR A CB  1 
ATOM 3450 O OG1 . THR C 3 273 ? 376.020 388.795 477.614 1.00 60.24  ? 273 THR A OG1 1 
ATOM 3451 C CG2 . THR C 3 273 ? 377.559 387.277 478.673 1.00 60.24  ? 273 THR A CG2 1 
ATOM 3452 N N   . ASP C 3 274 ? 373.525 387.619 476.895 1.00 61.95  ? 274 ASP A N   1 
ATOM 3453 C CA  . ASP C 3 274 ? 372.342 388.346 476.468 1.00 61.95  ? 274 ASP A CA  1 
ATOM 3454 C C   . ASP C 3 274 ? 371.820 387.730 475.183 1.00 61.95  ? 274 ASP A C   1 
ATOM 3455 O O   . ASP C 3 274 ? 372.562 387.099 474.430 1.00 61.95  ? 274 ASP A O   1 
ATOM 3456 C CB  . ASP C 3 274 ? 372.649 389.828 476.254 1.00 61.95  ? 274 ASP A CB  1 
ATOM 3457 C CG  . ASP C 3 274 ? 371.482 390.716 476.592 1.00 61.95  ? 274 ASP A CG  1 
ATOM 3458 O OD1 . ASP C 3 274 ? 370.343 390.209 476.622 1.00 61.95  ? 274 ASP A OD1 1 
ATOM 3459 O OD2 . ASP C 3 274 ? 371.703 391.921 476.823 1.00 61.95  ? 274 ASP A OD2 1 
ATOM 3460 N N   . ILE C 3 275 ? 370.528 387.928 474.935 1.00 57.96  ? 275 ILE A N   1 
ATOM 3461 C CA  . ILE C 3 275 ? 369.948 387.426 473.699 1.00 57.96  ? 275 ILE A CA  1 
ATOM 3462 C C   . ILE C 3 275 ? 370.275 388.361 472.535 1.00 57.96  ? 275 ILE A C   1 
ATOM 3463 O O   . ILE C 3 275 ? 370.501 387.903 471.410 1.00 57.96  ? 275 ILE A O   1 
ATOM 3464 C CB  . ILE C 3 275 ? 368.438 387.201 473.893 1.00 57.96  ? 275 ILE A CB  1 
ATOM 3465 C CG1 . ILE C 3 275 ? 367.766 386.727 472.607 1.00 57.96  ? 275 ILE A CG1 1 
ATOM 3466 C CG2 . ILE C 3 275 ? 367.763 388.437 474.457 1.00 57.96  ? 275 ILE A CG2 1 
ATOM 3467 C CD1 . ILE C 3 275 ? 366.310 386.395 472.777 1.00 57.96  ? 275 ILE A CD1 1 
ATOM 3468 N N   . ILE C 3 276 ? 370.374 389.661 472.783 1.00 58.27  ? 276 ILE A N   1 
ATOM 3469 C CA  . ILE C 3 276 ? 370.844 390.590 471.767 1.00 58.27  ? 276 ILE A CA  1 
ATOM 3470 C C   . ILE C 3 276 ? 372.356 390.467 471.624 1.00 58.27  ? 276 ILE A C   1 
ATOM 3471 O O   . ILE C 3 276 ? 372.959 391.068 470.736 1.00 58.27  ? 276 ILE A O   1 
ATOM 3472 C CB  . ILE C 3 276 ? 370.446 392.025 472.102 1.00 58.27  ? 276 ILE A CB  1 
ATOM 3473 C CG1 . ILE C 3 276 ? 371.360 392.582 473.194 1.00 58.27  ? 276 ILE A CG1 1 
ATOM 3474 C CG2 . ILE C 3 276 ? 369.004 392.074 472.536 1.00 58.27  ? 276 ILE A CG2 1 
ATOM 3475 C CD1 . ILE C 3 276 ? 371.043 393.999 473.612 1.00 58.27  ? 276 ILE A CD1 1 
ATOM 3476 N N   . ARG D 4 14  ? 335.733 363.301 455.566 1.00 93.36  ? 14  ARG B N   1 
ATOM 3477 C CA  . ARG D 4 14  ? 335.125 363.549 456.866 1.00 93.36  ? 14  ARG B CA  1 
ATOM 3478 C C   . ARG D 4 14  ? 334.214 362.400 457.260 1.00 93.36  ? 14  ARG B C   1 
ATOM 3479 O O   . ARG D 4 14  ? 333.618 361.757 456.394 1.00 93.36  ? 14  ARG B O   1 
ATOM 3480 C CB  . ARG D 4 14  ? 334.336 364.855 456.853 1.00 93.36  ? 14  ARG B CB  1 
ATOM 3481 C CG  . ARG D 4 14  ? 335.152 366.069 456.464 1.00 93.36  ? 14  ARG B CG  1 
ATOM 3482 C CD  . ARG D 4 14  ? 334.267 367.293 456.370 1.00 93.36  ? 14  ARG B CD  1 
ATOM 3483 N NE  . ARG D 4 14  ? 333.442 367.427 457.562 1.00 93.36  ? 14  ARG B NE  1 
ATOM 3484 C CZ  . ARG D 4 14  ? 333.639 368.339 458.503 1.00 93.36  ? 14  ARG B CZ  1 
ATOM 3485 N NH1 . ARG D 4 14  ? 334.628 369.212 458.386 1.00 93.36  ? 14  ARG B NH1 1 
ATOM 3486 N NH2 . ARG D 4 14  ? 332.842 368.383 459.558 1.00 93.36  ? 14  ARG B NH2 1 
ATOM 3487 N N   . SER D 4 15  ? 334.124 362.171 458.574 1.00 92.42  ? 15  SER B N   1 
ATOM 3488 C CA  . SER D 4 15  ? 333.294 361.132 459.192 1.00 92.42  ? 15  SER B CA  1 
ATOM 3489 C C   . SER D 4 15  ? 333.634 359.744 458.649 1.00 92.42  ? 15  SER B C   1 
ATOM 3490 O O   . SER D 4 15  ? 332.819 359.074 458.017 1.00 92.42  ? 15  SER B O   1 
ATOM 3491 C CB  . SER D 4 15  ? 331.798 361.437 459.037 1.00 92.42  ? 15  SER B CB  1 
ATOM 3492 O OG  . SER D 4 15  ? 331.348 362.325 460.047 1.00 92.42  ? 15  SER B OG  1 
ATOM 3493 N N   . ILE D 4 16  ? 334.861 359.329 458.901 1.00 88.71  ? 16  ILE B N   1 
ATOM 3494 C CA  . ILE D 4 16  ? 335.309 357.995 458.530 1.00 88.71  ? 16  ILE B CA  1 
ATOM 3495 C C   . ILE D 4 16  ? 334.870 357.021 459.611 1.00 88.71  ? 16  ILE B C   1 
ATOM 3496 O O   . ILE D 4 16  ? 334.612 357.413 460.753 1.00 88.71  ? 16  ILE B O   1 
ATOM 3497 C CB  . ILE D 4 16  ? 336.834 357.968 458.306 1.00 88.71  ? 16  ILE B CB  1 
ATOM 3498 C CG1 . ILE D 4 16  ? 337.598 357.944 459.625 1.00 88.71  ? 16  ILE B CG1 1 
ATOM 3499 C CG2 . ILE D 4 16  ? 337.266 359.176 457.500 1.00 88.71  ? 16  ILE B CG2 1 
ATOM 3500 C CD1 . ILE D 4 16  ? 339.090 357.890 459.447 1.00 88.71  ? 16  ILE B CD1 1 
ATOM 3501 N N   . THR D 4 17  ? 334.732 355.755 459.244 1.00 87.88  ? 17  THR B N   1 
ATOM 3502 C CA  . THR D 4 17  ? 334.281 354.732 460.171 1.00 87.88  ? 17  THR B CA  1 
ATOM 3503 C C   . THR D 4 17  ? 335.123 353.477 460.006 1.00 87.88  ? 17  THR B C   1 
ATOM 3504 O O   . THR D 4 17  ? 335.753 353.262 458.967 1.00 87.88  ? 17  THR B O   1 
ATOM 3505 C CB  . THR D 4 17  ? 332.791 354.412 459.975 1.00 87.88  ? 17  THR B CB  1 
ATOM 3506 O OG1 . THR D 4 17  ? 332.339 353.557 461.031 1.00 87.88  ? 17  THR B OG1 1 
ATOM 3507 C CG2 . THR D 4 17  ? 332.536 353.744 458.631 1.00 87.88  ? 17  THR B CG2 1 
ATOM 3508 N N   . LEU D 4 18  ? 335.150 352.664 461.057 1.00 85.66  ? 18  LEU B N   1 
ATOM 3509 C CA  . LEU D 4 18  ? 335.962 351.453 461.088 1.00 85.66  ? 18  LEU B CA  1 
ATOM 3510 C C   . LEU D 4 18  ? 335.340 350.501 462.095 1.00 85.66  ? 18  LEU B C   1 
ATOM 3511 O O   . LEU D 4 18  ? 335.532 350.667 463.302 1.00 85.66  ? 18  LEU B O   1 
ATOM 3512 C CB  . LEU D 4 18  ? 337.408 351.769 461.460 1.00 85.66  ? 18  LEU B CB  1 
ATOM 3513 C CG  . LEU D 4 18  ? 338.491 350.941 460.778 1.00 85.66  ? 18  LEU B CG  1 
ATOM 3514 C CD1 . LEU D 4 18  ? 338.306 350.950 459.271 1.00 85.66  ? 18  LEU B CD1 1 
ATOM 3515 C CD2 . LEU D 4 18  ? 339.853 351.479 461.151 1.00 85.66  ? 18  LEU B CD2 1 
ATOM 3516 N N   . GLY D 4 19  ? 334.610 349.506 461.608 1.00 87.30  ? 19  GLY B N   1 
ATOM 3517 C CA  . GLY D 4 19  ? 333.922 348.592 462.495 1.00 87.30  ? 19  GLY B CA  1 
ATOM 3518 C C   . GLY D 4 19  ? 332.716 349.243 463.134 1.00 87.30  ? 19  GLY B C   1 
ATOM 3519 O O   . GLY D 4 19  ? 331.813 349.704 462.432 1.00 87.30  ? 19  GLY B O   1 
ATOM 3520 N N   . ASN D 4 20  ? 332.693 349.302 464.460 1.00 87.77  ? 20  ASN B N   1 
ATOM 3521 C CA  . ASN D 4 20  ? 331.618 349.948 465.195 1.00 87.77  ? 20  ASN B CA  1 
ATOM 3522 C C   . ASN D 4 20  ? 332.132 351.177 465.931 1.00 87.77  ? 20  ASN B C   1 
ATOM 3523 O O   . ASN D 4 20  ? 331.764 351.441 467.074 1.00 87.77  ? 20  ASN B O   1 
ATOM 3524 C CB  . ASN D 4 20  ? 330.952 348.971 466.159 1.00 87.77  ? 20  ASN B CB  1 
ATOM 3525 C CG  . ASN D 4 20  ? 331.933 348.323 467.102 1.00 87.77  ? 20  ASN B CG  1 
ATOM 3526 O OD1 . ASN D 4 20  ? 333.034 347.956 466.708 1.00 87.77  ? 20  ASN B OD1 1 
ATOM 3527 N ND2 . ASN D 4 20  ? 331.534 348.164 468.356 1.00 87.77  ? 20  ASN B ND2 1 
ATOM 3528 N N   . SER D 4 21  ? 332.992 351.945 465.271 1.00 86.30  ? 21  SER B N   1 
ATOM 3529 C CA  . SER D 4 21  ? 333.509 353.192 465.811 1.00 86.30  ? 21  SER B CA  1 
ATOM 3530 C C   . SER D 4 21  ? 333.620 354.207 464.686 1.00 86.30  ? 21  SER B C   1 
ATOM 3531 O O   . SER D 4 21  ? 334.024 353.871 463.572 1.00 86.30  ? 21  SER B O   1 
ATOM 3532 C CB  . SER D 4 21  ? 334.871 352.998 466.465 1.00 86.30  ? 21  SER B CB  1 
ATOM 3533 O OG  . SER D 4 21  ? 335.894 353.130 465.500 1.00 86.30  ? 21  SER B OG  1 
ATOM 3534 N N   . THR D 4 22  ? 333.272 355.456 464.984 1.00 87.77  ? 22  THR B N   1 
ATOM 3535 C CA  . THR D 4 22  ? 333.208 356.485 463.956 1.00 87.77  ? 22  THR B CA  1 
ATOM 3536 C C   . THR D 4 22  ? 333.703 357.812 464.508 1.00 87.77  ? 22  THR B C   1 
ATOM 3537 O O   . THR D 4 22  ? 333.133 358.336 465.468 1.00 87.77  ? 22  THR B O   1 
ATOM 3538 C CB  . THR D 4 22  ? 331.777 356.638 463.431 1.00 87.77  ? 22  THR B CB  1 
ATOM 3539 O OG1 . THR D 4 22  ? 331.362 355.412 462.818 1.00 87.77  ? 22  THR B OG1 1 
ATOM 3540 C CG2 . THR D 4 22  ? 331.687 357.761 462.414 1.00 87.77  ? 22  THR B CG2 1 
ATOM 3541 N N   . ILE D 4 23  ? 334.759 358.352 463.901 1.00 84.42  ? 23  ILE B N   1 
ATOM 3542 C CA  . ILE D 4 23  ? 335.266 359.676 464.228 1.00 84.42  ? 23  ILE B CA  1 
ATOM 3543 C C   . ILE D 4 23  ? 335.126 360.558 462.995 1.00 84.42  ? 23  ILE B C   1 
ATOM 3544 O O   . ILE D 4 23  ? 334.884 360.078 461.891 1.00 84.42  ? 23  ILE B O   1 
ATOM 3545 C CB  . ILE D 4 23  ? 336.728 359.648 464.709 1.00 84.42  ? 23  ILE B CB  1 
ATOM 3546 C CG1 . ILE D 4 23  ? 337.681 359.479 463.528 1.00 84.42  ? 23  ILE B CG1 1 
ATOM 3547 C CG2 . ILE D 4 23  ? 336.940 358.534 465.713 1.00 84.42  ? 23  ILE B CG2 1 
ATOM 3548 C CD1 . ILE D 4 23  ? 339.078 359.970 463.804 1.00 84.42  ? 23  ILE B CD1 1 
ATOM 3549 N N   . THR D 4 24  ? 335.285 361.864 463.193 1.00 88.15  ? 24  THR B N   1 
ATOM 3550 C CA  . THR D 4 24  ? 335.231 362.817 462.092 1.00 88.15  ? 24  THR B CA  1 
ATOM 3551 C C   . THR D 4 24  ? 336.446 363.733 462.124 1.00 88.15  ? 24  THR B C   1 
ATOM 3552 O O   . THR D 4 24  ? 336.870 364.186 463.193 1.00 88.15  ? 24  THR B O   1 
ATOM 3553 C CB  . THR D 4 24  ? 333.933 363.635 462.120 1.00 88.15  ? 24  THR B CB  1 
ATOM 3554 O OG1 . THR D 4 24  ? 334.019 364.707 461.173 1.00 88.15  ? 24  THR B OG1 1 
ATOM 3555 C CG2 . THR D 4 24  ? 333.642 364.187 463.514 1.00 88.15  ? 24  THR B CG2 1 
ATOM 3556 N N   . THR D 4 25  ? 337.024 363.974 460.945 1.00 93.64  ? 25  THR B N   1 
ATOM 3557 C CA  . THR D 4 25  ? 338.167 364.863 460.774 1.00 93.64  ? 25  THR B CA  1 
ATOM 3558 C C   . THR D 4 25  ? 337.805 365.944 459.763 1.00 93.64  ? 25  THR B C   1 
ATOM 3559 O O   . THR D 4 25  ? 336.623 366.166 459.486 1.00 93.64  ? 25  THR B O   1 
ATOM 3560 C CB  . THR D 4 25  ? 339.413 364.110 460.288 1.00 93.64  ? 25  THR B CB  1 
ATOM 3561 O OG1 . THR D 4 25  ? 339.348 363.953 458.867 1.00 93.64  ? 25  THR B OG1 1 
ATOM 3562 C CG2 . THR D 4 25  ? 339.527 362.734 460.921 1.00 93.64  ? 25  THR B CG2 1 
ATOM 3563 N N   . GLN D 4 26  ? 338.802 366.627 459.214 1.00 95.25  ? 26  GLN B N   1 
ATOM 3564 C CA  . GLN D 4 26  ? 338.559 367.555 458.115 1.00 95.25  ? 26  GLN B CA  1 
ATOM 3565 C C   . GLN D 4 26  ? 338.766 366.876 456.762 1.00 95.25  ? 26  GLN B C   1 
ATOM 3566 O O   . GLN D 4 26  ? 338.625 367.500 455.709 1.00 95.25  ? 26  GLN B O   1 
ATOM 3567 C CB  . GLN D 4 26  ? 339.471 368.774 458.241 1.00 95.25  ? 26  GLN B CB  1 
ATOM 3568 C CG  . GLN D 4 26  ? 339.021 369.761 459.293 1.00 95.25  ? 26  GLN B CG  1 
ATOM 3569 C CD  . GLN D 4 26  ? 339.588 369.451 460.660 1.00 95.25  ? 26  GLN B CD  1 
ATOM 3570 O OE1 . GLN D 4 26  ? 340.072 368.347 460.910 1.00 95.25  ? 26  GLN B OE1 1 
ATOM 3571 N NE2 . GLN D 4 26  ? 339.530 370.427 461.559 1.00 95.25  ? 26  GLN B NE2 1 
ATOM 3572 N N   . ASN D 4 30  ? 346.150 367.453 456.537 1.00 67.99  ? 30  ASN B N   1 
ATOM 3573 C CA  . ASN D 4 30  ? 347.356 366.865 455.964 1.00 67.99  ? 30  ASN B CA  1 
ATOM 3574 C C   . ASN D 4 30  ? 347.948 365.784 456.865 1.00 67.99  ? 30  ASN B C   1 
ATOM 3575 O O   . ASN D 4 30  ? 347.999 365.933 458.082 1.00 67.99  ? 30  ASN B O   1 
ATOM 3576 C CB  . ASN D 4 30  ? 348.389 367.952 455.689 1.00 67.99  ? 30  ASN B CB  1 
ATOM 3577 C CG  . ASN D 4 30  ? 348.519 368.933 456.831 1.00 67.99  ? 30  ASN B CG  1 
ATOM 3578 O OD1 . ASN D 4 30  ? 347.847 368.808 457.854 1.00 67.99  ? 30  ASN B OD1 1 
ATOM 3579 N ND2 . ASN D 4 30  ? 349.384 369.923 456.660 1.00 67.99  ? 30  ASN B ND2 1 
ATOM 3580 N N   . VAL D 4 31  ? 348.405 364.696 456.250 1.00 62.74  ? 31  VAL B N   1 
ATOM 3581 C CA  . VAL D 4 31  ? 348.848 363.505 456.963 1.00 62.74  ? 31  VAL B CA  1 
ATOM 3582 C C   . VAL D 4 31  ? 350.309 363.254 456.633 1.00 62.74  ? 31  VAL B C   1 
ATOM 3583 O O   . VAL D 4 31  ? 350.671 363.145 455.457 1.00 62.74  ? 31  VAL B O   1 
ATOM 3584 C CB  . VAL D 4 31  ? 348.001 362.278 456.580 1.00 62.74  ? 31  VAL B CB  1 
ATOM 3585 C CG1 . VAL D 4 31  ? 348.593 361.017 457.172 1.00 62.74  ? 31  VAL B CG1 1 
ATOM 3586 C CG2 . VAL D 4 31  ? 346.565 362.471 457.013 1.00 62.74  ? 31  VAL B CG2 1 
ATOM 3587 N N   . VAL D 4 32  ? 351.145 363.159 457.662 1.00 59.53  ? 32  VAL B N   1 
ATOM 3588 C CA  . VAL D 4 32  ? 352.547 362.792 457.509 1.00 59.53  ? 32  VAL B CA  1 
ATOM 3589 C C   . VAL D 4 32  ? 352.674 361.290 457.711 1.00 59.53  ? 32  VAL B C   1 
ATOM 3590 O O   . VAL D 4 32  ? 352.202 360.741 458.709 1.00 59.53  ? 32  VAL B O   1 
ATOM 3591 C CB  . VAL D 4 32  ? 353.451 363.601 458.456 1.00 59.53  ? 32  VAL B CB  1 
ATOM 3592 C CG1 . VAL D 4 32  ? 352.913 363.636 459.863 1.00 59.53  ? 32  VAL B CG1 1 
ATOM 3593 C CG2 . VAL D 4 32  ? 354.847 363.022 458.471 1.00 59.53  ? 32  VAL B CG2 1 
ATOM 3594 N N   . VAL D 4 33  ? 353.262 360.610 456.736 1.00 62.03  ? 33  VAL B N   1 
ATOM 3595 C CA  . VAL D 4 33  ? 353.289 359.156 456.702 1.00 62.03  ? 33  VAL B CA  1 
ATOM 3596 C C   . VAL D 4 33  ? 354.726 358.675 456.865 1.00 62.03  ? 33  VAL B C   1 
ATOM 3597 O O   . VAL D 4 33  ? 355.591 358.959 456.027 1.00 62.03  ? 33  VAL B O   1 
ATOM 3598 C CB  . VAL D 4 33  ? 352.614 358.605 455.435 1.00 62.03  ? 33  VAL B CB  1 
ATOM 3599 C CG1 . VAL D 4 33  ? 353.055 359.341 454.172 1.00 62.03  ? 33  VAL B CG1 1 
ATOM 3600 C CG2 . VAL D 4 33  ? 352.893 357.128 455.297 1.00 62.03  ? 33  VAL B CG2 1 
ATOM 3601 N N   . GLY D 4 34  ? 354.976 358.008 457.998 1.00 60.12  ? 34  GLY B N   1 
ATOM 3602 C CA  . GLY D 4 34  ? 356.131 357.176 458.308 1.00 60.12  ? 34  GLY B CA  1 
ATOM 3603 C C   . GLY D 4 34  ? 357.498 357.581 457.816 1.00 60.12  ? 34  GLY B C   1 
ATOM 3604 O O   . GLY D 4 34  ? 357.991 358.670 458.116 1.00 60.12  ? 34  GLY B O   1 
ATOM 3605 N N   . TYR D 4 35  ? 358.116 356.690 457.050 1.00 58.75  ? 35  TYR B N   1 
ATOM 3606 C CA  . TYR D 4 35  ? 359.312 357.003 456.287 1.00 58.75  ? 35  TYR B CA  1 
ATOM 3607 C C   . TYR D 4 35  ? 359.054 356.940 454.791 1.00 58.75  ? 35  TYR B C   1 
ATOM 3608 O O   . TYR D 4 35  ? 359.906 356.477 454.029 1.00 58.75  ? 35  TYR B O   1 
ATOM 3609 C CB  . TYR D 4 35  ? 360.446 356.066 456.685 1.00 58.75  ? 35  TYR B CB  1 
ATOM 3610 C CG  . TYR D 4 35  ? 360.934 356.311 458.086 1.00 58.75  ? 35  TYR B CG  1 
ATOM 3611 C CD1 . TYR D 4 35  ? 361.880 357.288 458.346 1.00 58.75  ? 35  TYR B CD1 1 
ATOM 3612 C CD2 . TYR D 4 35  ? 360.440 355.577 459.151 1.00 58.75  ? 35  TYR B CD2 1 
ATOM 3613 C CE1 . TYR D 4 35  ? 362.324 357.519 459.624 1.00 58.75  ? 35  TYR B CE1 1 
ATOM 3614 C CE2 . TYR D 4 35  ? 360.880 355.802 460.430 1.00 58.75  ? 35  TYR B CE2 1 
ATOM 3615 C CZ  . TYR D 4 35  ? 361.819 356.772 460.658 1.00 58.75  ? 35  TYR B CZ  1 
ATOM 3616 O OH  . TYR D 4 35  ? 362.255 356.996 461.934 1.00 58.75  ? 35  TYR B OH  1 
ATOM 3617 N N   . GLY D 4 36  ? 357.886 357.396 454.358 1.00 65.18  ? 36  GLY B N   1 
ATOM 3618 C CA  . GLY D 4 36  ? 357.500 357.317 452.972 1.00 65.18  ? 36  GLY B CA  1 
ATOM 3619 C C   . GLY D 4 36  ? 356.824 356.026 452.575 1.00 65.18  ? 36  GLY B C   1 
ATOM 3620 O O   . GLY D 4 36  ? 356.365 355.913 451.432 1.00 65.18  ? 36  GLY B O   1 
ATOM 3621 N N   . VAL D 4 37  ? 356.739 355.052 453.477 1.00 72.38  ? 37  VAL B N   1 
ATOM 3622 C CA  . VAL D 4 37  ? 356.160 353.756 453.163 1.00 72.38  ? 37  VAL B CA  1 
ATOM 3623 C C   . VAL D 4 37  ? 354.829 353.619 453.881 1.00 72.38  ? 37  VAL B C   1 
ATOM 3624 O O   . VAL D 4 37  ? 354.584 354.241 454.920 1.00 72.38  ? 37  VAL B O   1 
ATOM 3625 C CB  . VAL D 4 37  ? 357.097 352.589 453.537 1.00 72.38  ? 37  VAL B CB  1 
ATOM 3626 C CG1 . VAL D 4 37  ? 358.365 352.642 452.708 1.00 72.38  ? 37  VAL B CG1 1 
ATOM 3627 C CG2 . VAL D 4 37  ? 357.426 352.625 455.005 1.00 72.38  ? 37  VAL B CG2 1 
ATOM 3628 N N   . TRP D 4 38  ? 353.993 352.833 453.326 1.00 86.75  ? 38  TRP B N   1 
ATOM 3629 C CA  . TRP D 4 38  ? 352.658 352.513 453.782 1.00 86.75  ? 38  TRP B CA  1 
ATOM 3630 C C   . TRP D 4 38  ? 352.656 351.155 454.470 1.00 86.75  ? 38  TRP B C   1 
ATOM 3631 O O   . TRP D 4 38  ? 353.427 350.269 454.093 1.00 86.75  ? 38  TRP B O   1 
ATOM 3632 C CB  . TRP D 4 38  ? 351.690 352.492 452.600 1.00 86.75  ? 38  TRP B CB  1 
ATOM 3633 C CG  . TRP D 4 38  ? 350.268 352.473 453.009 1.00 86.75  ? 38  TRP B CG  1 
ATOM 3634 C CD1 . TRP D 4 38  ? 349.460 351.381 453.123 1.00 86.75  ? 38  TRP B CD1 1 
ATOM 3635 C CD2 . TRP D 4 38  ? 349.470 353.602 453.364 1.00 86.75  ? 38  TRP B CD2 1 
ATOM 3636 N NE1 . TRP D 4 38  ? 348.207 351.761 453.530 1.00 86.75  ? 38  TRP B NE1 1 
ATOM 3637 C CE2 . TRP D 4 38  ? 348.188 353.122 453.685 1.00 86.75  ? 38  TRP B CE2 1 
ATOM 3638 C CE3 . TRP D 4 38  ? 349.715 354.974 453.439 1.00 86.75  ? 38  TRP B CE3 1 
ATOM 3639 C CZ2 . TRP D 4 38  ? 347.157 353.963 454.077 1.00 86.75  ? 38  TRP B CZ2 1 
ATOM 3640 C CZ3 . TRP D 4 38  ? 348.692 355.806 453.828 1.00 86.75  ? 38  TRP B CZ3 1 
ATOM 3641 C CH2 . TRP D 4 38  ? 347.428 355.300 454.143 1.00 86.75  ? 38  TRP B CH2 1 
ATOM 3642 N N   . PRO D 4 39  ? 351.838 350.965 455.507 1.00 87.75  ? 39  PRO B N   1 
ATOM 3643 C CA  . PRO D 4 39  ? 351.750 349.647 456.158 1.00 87.75  ? 39  PRO B CA  1 
ATOM 3644 C C   . PRO D 4 39  ? 351.154 348.599 455.228 1.00 87.75  ? 39  PRO B C   1 
ATOM 3645 O O   . PRO D 4 39  ? 350.041 348.754 454.723 1.00 87.75  ? 39  PRO B O   1 
ATOM 3646 C CB  . PRO D 4 39  ? 350.846 349.911 457.366 1.00 87.75  ? 39  PRO B CB  1 
ATOM 3647 C CG  . PRO D 4 39  ? 351.006 351.341 457.647 1.00 87.75  ? 39  PRO B CG  1 
ATOM 3648 C CD  . PRO D 4 39  ? 351.226 352.019 456.331 1.00 87.75  ? 39  PRO B CD  1 
ATOM 3649 N N   . GLU D 4 40  ? 351.907 347.526 455.007 1.00 98.35  ? 40  GLU B N   1 
ATOM 3650 C CA  . GLU D 4 40  ? 351.511 346.433 454.137 1.00 98.35  ? 40  GLU B CA  1 
ATOM 3651 C C   . GLU D 4 40  ? 351.719 345.127 454.895 1.00 98.35  ? 40  GLU B C   1 
ATOM 3652 O O   . GLU D 4 40  ? 352.431 345.077 455.901 1.00 98.35  ? 40  GLU B O   1 
ATOM 3653 C CB  . GLU D 4 40  ? 352.315 346.468 452.823 1.00 98.35  ? 40  GLU B CB  1 
ATOM 3654 C CG  . GLU D 4 40  ? 351.784 345.639 451.638 1.00 98.35  ? 40  GLU B CG  1 
ATOM 3655 C CD  . GLU D 4 40  ? 350.286 345.789 451.405 1.00 98.35  ? 40  GLU B CD  1 
ATOM 3656 O OE1 . GLU D 4 40  ? 349.505 344.977 451.946 1.00 98.35  ? 40  GLU B OE1 1 
ATOM 3657 O OE2 . GLU D 4 40  ? 349.890 346.716 450.669 1.00 98.35  ? 40  GLU B OE2 1 
ATOM 3658 N N   . TYR D 4 41  ? 351.078 344.063 454.417 1.00 103.65 ? 41  TYR B N   1 
ATOM 3659 C CA  . TYR D 4 41  ? 351.205 342.742 455.010 1.00 103.65 ? 41  TYR B CA  1 
ATOM 3660 C C   . TYR D 4 41  ? 352.587 342.152 454.723 1.00 103.65 ? 41  TYR B C   1 
ATOM 3661 O O   . TYR D 4 41  ? 353.382 342.699 453.955 1.00 103.65 ? 41  TYR B O   1 
ATOM 3662 C CB  . TYR D 4 41  ? 350.093 341.833 454.496 1.00 103.65 ? 41  TYR B CB  1 
ATOM 3663 C CG  . TYR D 4 41  ? 348.813 341.960 455.287 1.00 103.65 ? 41  TYR B CG  1 
ATOM 3664 C CD1 . TYR D 4 41  ? 347.891 342.957 454.999 1.00 103.65 ? 41  TYR B CD1 1 
ATOM 3665 C CD2 . TYR D 4 41  ? 348.534 341.088 456.331 1.00 103.65 ? 41  TYR B CD2 1 
ATOM 3666 C CE1 . TYR D 4 41  ? 346.726 343.076 455.726 1.00 103.65 ? 41  TYR B CE1 1 
ATOM 3667 C CE2 . TYR D 4 41  ? 347.373 341.199 457.058 1.00 103.65 ? 41  TYR B CE2 1 
ATOM 3668 C CZ  . TYR D 4 41  ? 346.475 342.194 456.753 1.00 103.65 ? 41  TYR B CZ  1 
ATOM 3669 O OH  . TYR D 4 41  ? 345.320 342.302 457.486 1.00 103.65 ? 41  TYR B OH  1 
ATOM 3670 N N   . LEU D 4 42  ? 352.864 341.005 455.341 1.00 103.98 ? 42  LEU B N   1 
ATOM 3671 C CA  . LEU D 4 42  ? 354.191 340.380 455.339 1.00 103.98 ? 42  LEU B CA  1 
ATOM 3672 C C   . LEU D 4 42  ? 354.691 339.950 453.958 1.00 103.98 ? 42  LEU B C   1 
ATOM 3673 O O   . LEU D 4 42  ? 353.932 339.901 452.992 1.00 103.98 ? 42  LEU B O   1 
ATOM 3674 C CB  . LEU D 4 42  ? 354.206 339.155 456.264 1.00 103.98 ? 42  LEU B CB  1 
ATOM 3675 C CG  . LEU D 4 42  ? 353.618 337.804 455.814 1.00 103.98 ? 42  LEU B CG  1 
ATOM 3676 C CD1 . LEU D 4 42  ? 354.028 336.709 456.787 1.00 103.98 ? 42  LEU B CD1 1 
ATOM 3677 C CD2 . LEU D 4 42  ? 352.099 337.799 455.661 1.00 103.98 ? 42  LEU B CD2 1 
ATOM 3678 N N   . ASP D 4 51  ? 355.758 329.625 460.878 1.00 118.52 ? 51  ASP B N   1 
ATOM 3679 C CA  . ASP D 4 51  ? 354.801 328.780 460.171 1.00 118.52 ? 51  ASP B CA  1 
ATOM 3680 C C   . ASP D 4 51  ? 353.934 329.613 459.231 1.00 118.52 ? 51  ASP B C   1 
ATOM 3681 O O   . ASP D 4 51  ? 354.399 330.609 458.681 1.00 118.52 ? 51  ASP B O   1 
ATOM 3682 C CB  . ASP D 4 51  ? 353.938 327.998 461.169 1.00 118.52 ? 51  ASP B CB  1 
ATOM 3683 C CG  . ASP D 4 51  ? 353.183 328.897 462.125 1.00 118.52 ? 51  ASP B CG  1 
ATOM 3684 O OD1 . ASP D 4 51  ? 353.776 329.330 463.134 1.00 118.52 ? 51  ASP B OD1 1 
ATOM 3685 O OD2 . ASP D 4 51  ? 351.993 329.167 461.863 1.00 118.52 ? 51  ASP B OD2 1 
ATOM 3686 N N   . GLN D 4 52  ? 352.672 329.186 459.025 1.00 122.14 ? 52  GLN B N   1 
ATOM 3687 C CA  . GLN D 4 52  ? 351.747 329.981 458.227 1.00 122.14 ? 52  GLN B CA  1 
ATOM 3688 C C   . GLN D 4 52  ? 350.871 330.831 459.135 1.00 122.14 ? 52  GLN B C   1 
ATOM 3689 O O   . GLN D 4 52  ? 350.042 330.284 459.878 1.00 122.14 ? 52  GLN B O   1 
ATOM 3690 C CB  . GLN D 4 52  ? 350.874 329.087 457.351 1.00 122.14 ? 52  GLN B CB  1 
ATOM 3691 C CG  . GLN D 4 52  ? 351.614 328.399 456.216 1.00 122.14 ? 52  GLN B CG  1 
ATOM 3692 C CD  . GLN D 4 52  ? 350.916 327.137 455.750 1.00 122.14 ? 52  GLN B CD  1 
ATOM 3693 O OE1 . GLN D 4 52  ? 349.877 326.758 456.286 1.00 122.14 ? 52  GLN B OE1 1 
ATOM 3694 N NE2 . GLN D 4 52  ? 351.482 326.483 454.742 1.00 122.14 ? 52  GLN B NE2 1 
ATOM 3695 N N   . PRO D 4 53  ? 351.021 332.152 459.111 1.00 119.73 ? 53  PRO B N   1 
ATOM 3696 C CA  . PRO D 4 53  ? 350.224 333.012 459.986 1.00 119.73 ? 53  PRO B CA  1 
ATOM 3697 C C   . PRO D 4 53  ? 349.003 333.459 459.196 1.00 119.73 ? 53  PRO B C   1 
ATOM 3698 O O   . PRO D 4 53  ? 349.042 333.660 457.981 1.00 119.73 ? 53  PRO B O   1 
ATOM 3699 C CB  . PRO D 4 53  ? 351.168 334.197 460.225 1.00 119.73 ? 53  PRO B CB  1 
ATOM 3700 C CG  . PRO D 4 53  ? 351.932 334.310 458.972 1.00 119.73 ? 53  PRO B CG  1 
ATOM 3701 C CD  . PRO D 4 53  ? 352.085 332.911 458.429 1.00 119.73 ? 53  PRO B CD  1 
ATOM 3702 N N   . THR D 4 54  ? 347.898 333.608 459.921 1.00 117.46 ? 54  THR B N   1 
ATOM 3703 C CA  . THR D 4 54  ? 346.658 334.145 459.368 1.00 117.46 ? 54  THR B CA  1 
ATOM 3704 C C   . THR D 4 54  ? 346.361 335.458 460.060 1.00 117.46 ? 54  THR B C   1 
ATOM 3705 O O   . THR D 4 54  ? 346.980 335.760 461.081 1.00 117.46 ? 54  THR B O   1 
ATOM 3706 C CB  . THR D 4 54  ? 345.515 333.135 459.528 1.00 117.46 ? 54  THR B CB  1 
ATOM 3707 O OG1 . THR D 4 54  ? 344.370 333.607 458.810 1.00 117.46 ? 54  THR B OG1 1 
ATOM 3708 C CG2 . THR D 4 54  ? 345.105 332.994 460.989 1.00 117.46 ? 54  THR B CG2 1 
ATOM 3709 N N   . GLN D 4 55  ? 345.447 336.255 459.511 1.00 117.53 ? 55  GLN B N   1 
ATOM 3710 C CA  . GLN D 4 55  ? 345.167 337.593 460.034 1.00 117.53 ? 55  GLN B CA  1 
ATOM 3711 C C   . GLN D 4 55  ? 343.788 337.779 460.661 1.00 117.53 ? 55  GLN B C   1 
ATOM 3712 O O   . GLN D 4 55  ? 342.815 337.117 460.254 1.00 117.53 ? 55  GLN B O   1 
ATOM 3713 C CB  . GLN D 4 55  ? 345.340 338.477 458.792 1.00 117.53 ? 55  GLN B CB  1 
ATOM 3714 C CG  . GLN D 4 55  ? 344.184 338.539 457.773 1.00 117.53 ? 55  GLN B CG  1 
ATOM 3715 C CD  . GLN D 4 55  ? 344.120 337.338 456.835 1.00 117.53 ? 55  GLN B CD  1 
ATOM 3716 O OE1 . GLN D 4 55  ? 344.113 336.185 457.268 1.00 117.53 ? 55  GLN B OE1 1 
ATOM 3717 N NE2 . GLN D 4 55  ? 344.071 337.611 455.538 1.00 117.53 ? 55  GLN B NE2 1 
ATOM 3718 N N   . PRO D 4 56  ? 343.676 338.580 461.727 1.00 116.80 ? 56  PRO B N   1 
ATOM 3719 C CA  . PRO D 4 56  ? 342.356 339.060 462.154 1.00 116.80 ? 56  PRO B CA  1 
ATOM 3720 C C   . PRO D 4 56  ? 342.023 340.401 461.518 1.00 116.80 ? 56  PRO B C   1 
ATOM 3721 O O   . PRO D 4 56  ? 342.869 341.301 461.482 1.00 116.80 ? 56  PRO B O   1 
ATOM 3722 C CB  . PRO D 4 56  ? 342.498 339.167 463.675 1.00 116.80 ? 56  PRO B CB  1 
ATOM 3723 C CG  . PRO D 4 56  ? 343.961 339.420 463.902 1.00 116.80 ? 56  PRO B CG  1 
ATOM 3724 C CD  . PRO D 4 56  ? 344.723 338.849 462.730 1.00 116.80 ? 56  PRO B CD  1 
ATOM 3725 N N   . ASP D 4 57  ? 340.807 340.553 460.997 1.00 119.40 ? 57  ASP B N   1 
ATOM 3726 C CA  . ASP D 4 57  ? 340.470 341.809 460.341 1.00 119.40 ? 57  ASP B CA  1 
ATOM 3727 C C   . ASP D 4 57  ? 339.170 342.401 460.868 1.00 119.40 ? 57  ASP B C   1 
ATOM 3728 O O   . ASP D 4 57  ? 339.094 343.609 461.095 1.00 119.40 ? 57  ASP B O   1 
ATOM 3729 C CB  . ASP D 4 57  ? 340.424 341.614 458.818 1.00 119.40 ? 57  ASP B CB  1 
ATOM 3730 C CG  . ASP D 4 57  ? 339.401 340.587 458.378 1.00 119.40 ? 57  ASP B CG  1 
ATOM 3731 O OD1 . ASP D 4 57  ? 338.210 340.942 458.271 1.00 119.40 ? 57  ASP B OD1 1 
ATOM 3732 O OD2 . ASP D 4 57  ? 339.789 339.424 458.142 1.00 119.40 ? 57  ASP B OD2 1 
ATOM 3733 N N   . VAL D 4 58  ? 338.149 341.575 461.098 1.00 116.87 ? 58  VAL B N   1 
ATOM 3734 C CA  . VAL D 4 58  ? 336.878 342.117 461.566 1.00 116.87 ? 58  VAL B CA  1 
ATOM 3735 C C   . VAL D 4 58  ? 336.898 342.425 463.055 1.00 116.87 ? 58  VAL B C   1 
ATOM 3736 O O   . VAL D 4 58  ? 336.237 343.373 463.493 1.00 116.87 ? 58  VAL B O   1 
ATOM 3737 C CB  . VAL D 4 58  ? 335.711 341.167 461.241 1.00 116.87 ? 58  VAL B CB  1 
ATOM 3738 C CG1 . VAL D 4 58  ? 335.297 341.308 459.784 1.00 116.87 ? 58  VAL B CG1 1 
ATOM 3739 C CG2 . VAL D 4 58  ? 336.092 339.723 461.539 1.00 116.87 ? 58  VAL B CG2 1 
ATOM 3740 N N   . ALA D 4 59  ? 337.642 341.660 463.846 1.00 108.59 ? 59  ALA B N   1 
ATOM 3741 C CA  . ALA D 4 59  ? 337.552 341.797 465.291 1.00 108.59 ? 59  ALA B CA  1 
ATOM 3742 C C   . ALA D 4 59  ? 338.390 342.946 465.826 1.00 108.59 ? 59  ALA B C   1 
ATOM 3743 O O   . ALA D 4 59  ? 338.247 343.310 466.997 1.00 108.59 ? 59  ALA B O   1 
ATOM 3744 C CB  . ALA D 4 59  ? 337.977 340.491 465.960 1.00 108.59 ? 59  ALA B CB  1 
ATOM 3745 N N   . THR D 4 60  ? 339.262 343.528 465.004 1.00 103.10 ? 60  THR B N   1 
ATOM 3746 C CA  . THR D 4 60  ? 340.310 344.394 465.526 1.00 103.10 ? 60  THR B CA  1 
ATOM 3747 C C   . THR D 4 60  ? 340.218 345.847 465.101 1.00 103.10 ? 60  THR B C   1 
ATOM 3748 O O   . THR D 4 60  ? 340.285 346.716 465.969 1.00 103.10 ? 60  THR B O   1 
ATOM 3749 C CB  . THR D 4 60  ? 341.694 343.865 465.128 1.00 103.10 ? 60  THR B CB  1 
ATOM 3750 O OG1 . THR D 4 60  ? 341.802 343.819 463.700 1.00 103.10 ? 60  THR B OG1 1 
ATOM 3751 C CG2 . THR D 4 60  ? 341.932 342.477 465.701 1.00 103.10 ? 60  THR B CG2 1 
ATOM 3752 N N   . CYS D 4 61  ? 340.083 346.144 463.803 1.00 95.86  ? 61  CYS B N   1 
ATOM 3753 C CA  . CYS D 4 61  ? 340.335 347.500 463.308 1.00 95.86  ? 61  CYS B CA  1 
ATOM 3754 C C   . CYS D 4 61  ? 339.181 348.417 463.704 1.00 95.86  ? 61  CYS B C   1 
ATOM 3755 O O   . CYS D 4 61  ? 338.101 348.432 463.108 1.00 95.86  ? 61  CYS B O   1 
ATOM 3756 C CB  . CYS D 4 61  ? 340.575 347.526 461.800 1.00 95.86  ? 61  CYS B CB  1 
ATOM 3757 S SG  . CYS D 4 61  ? 339.356 346.741 460.729 1.00 95.86  ? 61  CYS B SG  1 
ATOM 3758 N N   . ARG D 4 62  ? 339.425 349.187 464.757 1.00 80.35  ? 62  ARG B N   1 
ATOM 3759 C CA  . ARG D 4 62  ? 338.496 350.194 465.233 1.00 80.35  ? 62  ARG B CA  1 
ATOM 3760 C C   . ARG D 4 62  ? 339.305 351.207 466.017 1.00 80.35  ? 62  ARG B C   1 
ATOM 3761 O O   . ARG D 4 62  ? 340.419 350.926 466.456 1.00 80.35  ? 62  ARG B O   1 
ATOM 3762 C CB  . ARG D 4 62  ? 337.386 349.588 466.092 1.00 80.35  ? 62  ARG B CB  1 
ATOM 3763 C CG  . ARG D 4 62  ? 337.887 348.674 467.174 1.00 80.35  ? 62  ARG B CG  1 
ATOM 3764 C CD  . ARG D 4 62  ? 336.741 348.100 467.972 1.00 80.35  ? 62  ARG B CD  1 
ATOM 3765 N NE  . ARG D 4 62  ? 335.785 349.126 468.361 1.00 80.35  ? 62  ARG B NE  1 
ATOM 3766 C CZ  . ARG D 4 62  ? 335.907 349.892 469.437 1.00 80.35  ? 62  ARG B CZ  1 
ATOM 3767 N NH1 . ARG D 4 62  ? 336.948 349.753 470.240 1.00 80.35  ? 62  ARG B NH1 1 
ATOM 3768 N NH2 . ARG D 4 62  ? 334.986 350.799 469.712 1.00 80.35  ? 62  ARG B NH2 1 
ATOM 3769 N N   . PHE D 4 63  ? 338.738 352.390 466.182 1.00 74.01  ? 63  PHE B N   1 
ATOM 3770 C CA  . PHE D 4 63  ? 339.451 353.502 466.789 1.00 74.01  ? 63  PHE B CA  1 
ATOM 3771 C C   . PHE D 4 63  ? 339.399 353.366 468.304 1.00 74.01  ? 63  PHE B C   1 
ATOM 3772 O O   . PHE D 4 63  ? 338.373 353.648 468.924 1.00 74.01  ? 63  PHE B O   1 
ATOM 3773 C CB  . PHE D 4 63  ? 338.851 354.821 466.324 1.00 74.01  ? 63  PHE B CB  1 
ATOM 3774 C CG  . PHE D 4 63  ? 339.075 355.094 464.876 1.00 74.01  ? 63  PHE B CG  1 
ATOM 3775 C CD1 . PHE D 4 63  ? 340.329 355.427 464.415 1.00 74.01  ? 63  PHE B CD1 1 
ATOM 3776 C CD2 . PHE D 4 63  ? 338.037 355.006 463.972 1.00 74.01  ? 63  PHE B CD2 1 
ATOM 3777 C CE1 . PHE D 4 63  ? 340.544 355.673 463.083 1.00 74.01  ? 63  PHE B CE1 1 
ATOM 3778 C CE2 . PHE D 4 63  ? 338.247 355.250 462.636 1.00 74.01  ? 63  PHE B CE2 1 
ATOM 3779 C CZ  . PHE D 4 63  ? 339.500 355.581 462.193 1.00 74.01  ? 63  PHE B CZ  1 
ATOM 3780 N N   . TYR D 4 64  ? 340.500 352.930 468.898 1.00 72.29  ? 64  TYR B N   1 
ATOM 3781 C CA  . TYR D 4 64  ? 340.623 352.864 470.347 1.00 72.29  ? 64  TYR B CA  1 
ATOM 3782 C C   . TYR D 4 64  ? 341.009 354.247 470.838 1.00 72.29  ? 64  TYR B C   1 
ATOM 3783 O O   . TYR D 4 64  ? 342.080 354.754 470.498 1.00 72.29  ? 64  TYR B O   1 
ATOM 3784 C CB  . TYR D 4 64  ? 341.651 351.815 470.759 1.00 72.29  ? 64  TYR B CB  1 
ATOM 3785 C CG  . TYR D 4 64  ? 341.244 350.427 470.350 1.00 72.29  ? 64  TYR B CG  1 
ATOM 3786 C CD1 . TYR D 4 64  ? 340.361 349.691 471.121 1.00 72.29  ? 64  TYR B CD1 1 
ATOM 3787 C CD2 . TYR D 4 64  ? 341.719 349.864 469.180 1.00 72.29  ? 64  TYR B CD2 1 
ATOM 3788 C CE1 . TYR D 4 64  ? 339.971 348.434 470.745 1.00 72.29  ? 64  TYR B CE1 1 
ATOM 3789 C CE2 . TYR D 4 64  ? 341.335 348.608 468.794 1.00 72.29  ? 64  TYR B CE2 1 
ATOM 3790 C CZ  . TYR D 4 64  ? 340.461 347.896 469.580 1.00 72.29  ? 64  TYR B CZ  1 
ATOM 3791 O OH  . TYR D 4 64  ? 340.069 346.639 469.193 1.00 72.29  ? 64  TYR B OH  1 
ATOM 3792 N N   . THR D 4 65  ? 340.139 354.862 471.624 1.00 61.80  ? 65  THR B N   1 
ATOM 3793 C CA  . THR D 4 65  ? 340.326 356.231 472.079 1.00 61.80  ? 65  THR B CA  1 
ATOM 3794 C C   . THR D 4 65  ? 340.786 356.215 473.528 1.00 61.80  ? 65  THR B C   1 
ATOM 3795 O O   . THR D 4 65  ? 340.031 355.823 474.420 1.00 61.80  ? 65  THR B O   1 
ATOM 3796 C CB  . THR D 4 65  ? 339.037 357.030 471.935 1.00 61.80  ? 65  THR B CB  1 
ATOM 3797 O OG1 . THR D 4 65  ? 338.606 356.999 470.574 1.00 61.80  ? 65  THR B OG1 1 
ATOM 3798 C CG2 . THR D 4 65  ? 339.271 358.457 472.331 1.00 61.80  ? 65  THR B CG2 1 
ATOM 3799 N N   . LEU D 4 66  ? 342.020 356.642 473.760 1.00 59.06  ? 66  LEU B N   1 
ATOM 3800 C CA  . LEU D 4 66  ? 342.490 356.833 475.119 1.00 59.06  ? 66  LEU B CA  1 
ATOM 3801 C C   . LEU D 4 66  ? 341.829 358.067 475.721 1.00 59.06  ? 66  LEU B C   1 
ATOM 3802 O O   . LEU D 4 66  ? 341.333 358.945 475.010 1.00 59.06  ? 66  LEU B O   1 
ATOM 3803 C CB  . LEU D 4 66  ? 344.005 356.993 475.142 1.00 59.06  ? 66  LEU B CB  1 
ATOM 3804 C CG  . LEU D 4 66  ? 344.802 356.051 474.252 1.00 59.06  ? 66  LEU B CG  1 
ATOM 3805 C CD1 . LEU D 4 66  ? 346.233 356.503 474.229 1.00 59.06  ? 66  LEU B CD1 1 
ATOM 3806 C CD2 . LEU D 4 66  ? 344.704 354.647 474.771 1.00 59.06  ? 66  LEU B CD2 1 
ATOM 3807 N N   . GLU D 4 67  ? 341.822 358.135 477.047 1.00 60.64  ? 67  GLU B N   1 
ATOM 3808 C CA  . GLU D 4 67  ? 341.193 359.269 477.699 1.00 60.64  ? 67  GLU B CA  1 
ATOM 3809 C C   . GLU D 4 67  ? 342.067 360.509 477.566 1.00 60.64  ? 67  GLU B C   1 
ATOM 3810 O O   . GLU D 4 67  ? 343.267 360.431 477.299 1.00 60.64  ? 67  GLU B O   1 
ATOM 3811 C CB  . GLU D 4 67  ? 340.921 358.973 479.166 1.00 60.64  ? 67  GLU B CB  1 
ATOM 3812 C CG  . GLU D 4 67  ? 342.127 358.559 479.938 1.00 60.64  ? 67  GLU B CG  1 
ATOM 3813 C CD  . GLU D 4 67  ? 341.892 358.647 481.422 1.00 60.64  ? 67  GLU B CD  1 
ATOM 3814 O OE1 . GLU D 4 67  ? 341.428 359.709 481.883 1.00 60.64  ? 67  GLU B OE1 1 
ATOM 3815 O OE2 . GLU D 4 67  ? 342.155 357.651 482.128 1.00 60.64  ? 67  GLU B OE2 1 
ATOM 3816 N N   . SER D 4 68  ? 341.444 361.666 477.745 1.00 53.40  ? 68  SER B N   1 
ATOM 3817 C CA  . SER D 4 68  ? 342.088 362.929 477.434 1.00 53.40  ? 68  SER B CA  1 
ATOM 3818 C C   . SER D 4 68  ? 342.912 363.424 478.607 1.00 53.40  ? 68  SER B C   1 
ATOM 3819 O O   . SER D 4 68  ? 342.552 363.219 479.768 1.00 53.40  ? 68  SER B O   1 
ATOM 3820 C CB  . SER D 4 68  ? 341.051 363.980 477.054 1.00 53.40  ? 68  SER B CB  1 
ATOM 3821 O OG  . SER D 4 68  ? 340.685 363.849 475.695 1.00 53.40  ? 68  SER B OG  1 
ATOM 3822 N N   . VAL D 4 69  ? 344.016 364.072 478.295 1.00 46.46  ? 69  VAL B N   1 
ATOM 3823 C CA  . VAL D 4 69  ? 344.862 364.713 479.286 1.00 46.46  ? 69  VAL B CA  1 
ATOM 3824 C C   . VAL D 4 69  ? 344.635 366.211 479.210 1.00 46.46  ? 69  VAL B C   1 
ATOM 3825 O O   . VAL D 4 69  ? 344.226 366.748 478.178 1.00 46.46  ? 69  VAL B O   1 
ATOM 3826 C CB  . VAL D 4 69  ? 346.343 364.351 479.075 1.00 46.46  ? 69  VAL B CB  1 
ATOM 3827 C CG1 . VAL D 4 69  ? 346.521 362.868 479.219 1.00 46.46  ? 69  VAL B CG1 1 
ATOM 3828 C CG2 . VAL D 4 69  ? 346.804 364.788 477.706 1.00 46.46  ? 69  VAL B CG2 1 
ATOM 3829 N N   . GLN D 4 70  ? 344.879 366.891 480.318 1.00 46.13  ? 70  GLN B N   1 
ATOM 3830 C CA  . GLN D 4 70  ? 344.606 368.313 480.432 1.00 46.13  ? 70  GLN B CA  1 
ATOM 3831 C C   . GLN D 4 70  ? 345.912 369.086 480.340 1.00 46.13  ? 70  GLN B C   1 
ATOM 3832 O O   . GLN D 4 70  ? 346.803 368.905 481.172 1.00 46.13  ? 70  GLN B O   1 
ATOM 3833 C CB  . GLN D 4 70  ? 343.884 368.609 481.740 1.00 46.13  ? 70  GLN B CB  1 
ATOM 3834 C CG  . GLN D 4 70  ? 342.580 367.858 481.867 1.00 46.13  ? 70  GLN B CG  1 
ATOM 3835 C CD  . GLN D 4 70  ? 341.854 368.159 483.154 1.00 46.13  ? 70  GLN B CD  1 
ATOM 3836 O OE1 . GLN D 4 70  ? 342.165 367.597 484.202 1.00 46.13  ? 70  GLN B OE1 1 
ATOM 3837 N NE2 . GLN D 4 70  ? 340.878 369.053 483.085 1.00 46.13  ? 70  GLN B NE2 1 
ATOM 3838 N N   . TRP D 4 71  ? 346.017 369.939 479.328 1.00 42.79  ? 71  TRP B N   1 
ATOM 3839 C CA  . TRP D 4 71  ? 347.197 370.763 479.091 1.00 42.79  ? 71  TRP B CA  1 
ATOM 3840 C C   . TRP D 4 71  ? 347.049 372.031 479.916 1.00 42.79  ? 71  TRP B C   1 
ATOM 3841 O O   . TRP D 4 71  ? 346.342 372.956 479.526 1.00 42.79  ? 71  TRP B O   1 
ATOM 3842 C CB  . TRP D 4 71  ? 347.323 371.067 477.604 1.00 42.79  ? 71  TRP B CB  1 
ATOM 3843 C CG  . TRP D 4 71  ? 348.504 371.869 477.187 1.00 42.79  ? 71  TRP B CG  1 
ATOM 3844 C CD1 . TRP D 4 71  ? 349.618 372.142 477.911 1.00 42.79  ? 71  TRP B CD1 1 
ATOM 3845 C CD2 . TRP D 4 71  ? 348.694 372.485 475.920 1.00 42.79  ? 71  TRP B CD2 1 
ATOM 3846 N NE1 . TRP D 4 71  ? 350.483 372.901 477.181 1.00 42.79  ? 71  TRP B NE1 1 
ATOM 3847 C CE2 . TRP D 4 71  ? 349.937 373.122 475.949 1.00 42.79  ? 71  TRP B CE2 1 
ATOM 3848 C CE3 . TRP D 4 71  ? 347.927 372.561 474.762 1.00 42.79  ? 71  TRP B CE3 1 
ATOM 3849 C CZ2 . TRP D 4 71  ? 350.430 373.824 474.871 1.00 42.79  ? 71  TRP B CZ2 1 
ATOM 3850 C CZ3 . TRP D 4 71  ? 348.416 373.256 473.696 1.00 42.79  ? 71  TRP B CZ3 1 
ATOM 3851 C CH2 . TRP D 4 71  ? 349.657 373.879 473.754 1.00 42.79  ? 71  TRP B CH2 1 
ATOM 3852 N N   . MET D 4 72  ? 347.723 372.082 481.054 1.00 48.28  ? 72  MET B N   1 
ATOM 3853 C CA  . MET D 4 72  ? 347.659 373.248 481.916 1.00 48.28  ? 72  MET B CA  1 
ATOM 3854 C C   . MET D 4 72  ? 348.883 374.126 481.675 1.00 48.28  ? 72  MET B C   1 
ATOM 3855 O O   . MET D 4 72  ? 349.695 373.860 480.790 1.00 48.28  ? 72  MET B O   1 
ATOM 3856 C CB  . MET D 4 72  ? 347.529 372.810 483.368 1.00 48.28  ? 72  MET B CB  1 
ATOM 3857 C CG  . MET D 4 72  ? 346.234 372.101 483.654 1.00 48.28  ? 72  MET B CG  1 
ATOM 3858 S SD  . MET D 4 72  ? 346.273 371.173 485.184 1.00 48.28  ? 72  MET B SD  1 
ATOM 3859 C CE  . MET D 4 72  ? 344.558 370.672 485.289 1.00 48.28  ? 72  MET B CE  1 
ATOM 3860 N N   . LYS D 4 73  ? 349.025 375.192 482.462 1.00 49.07  ? 73  LYS B N   1 
ATOM 3861 C CA  . LYS D 4 73  ? 350.169 376.082 482.303 1.00 49.07  ? 73  LYS B CA  1 
ATOM 3862 C C   . LYS D 4 73  ? 351.444 375.434 482.817 1.00 49.07  ? 73  LYS B C   1 
ATOM 3863 O O   . LYS D 4 73  ? 352.507 375.556 482.200 1.00 49.07  ? 73  LYS B O   1 
ATOM 3864 C CB  . LYS D 4 73  ? 349.917 377.398 483.032 1.00 49.07  ? 73  LYS B CB  1 
ATOM 3865 C CG  . LYS D 4 73  ? 349.487 378.535 482.136 1.00 49.07  ? 73  LYS B CG  1 
ATOM 3866 C CD  . LYS D 4 73  ? 349.442 379.840 482.898 1.00 49.07  ? 73  LYS B CD  1 
ATOM 3867 C CE  . LYS D 4 73  ? 348.596 380.862 482.173 1.00 49.07  ? 73  LYS B CE  1 
ATOM 3868 N NZ  . LYS D 4 73  ? 348.347 382.069 483.001 1.00 49.07  ? 73  LYS B NZ  1 
ATOM 3869 N N   . ASN D 4 74  ? 351.364 374.752 483.953 1.00 49.90  ? 74  ASN B N   1 
ATOM 3870 C CA  . ASN D 4 74  ? 352.520 374.074 484.530 1.00 49.90  ? 74  ASN B CA  1 
ATOM 3871 C C   . ASN D 4 74  ? 352.588 372.616 484.100 1.00 49.90  ? 74  ASN B C   1 
ATOM 3872 O O   . ASN D 4 74  ? 352.672 371.712 484.924 1.00 49.90  ? 74  ASN B O   1 
ATOM 3873 C CB  . ASN D 4 74  ? 352.480 374.193 486.045 1.00 49.90  ? 74  ASN B CB  1 
ATOM 3874 C CG  . ASN D 4 74  ? 351.133 373.822 486.619 1.00 49.90  ? 74  ASN B CG  1 
ATOM 3875 O OD1 . ASN D 4 74  ? 350.174 373.613 485.883 1.00 49.90  ? 74  ASN B OD1 1 
ATOM 3876 N ND2 . ASN D 4 74  ? 351.055 373.737 487.942 1.00 49.90  ? 74  ASN B ND2 1 
ATOM 3877 N N   . SER D 4 75  ? 352.543 372.378 482.797 1.00 47.13  ? 75  SER B N   1 
ATOM 3878 C CA  . SER D 4 75  ? 352.655 371.041 482.239 1.00 47.13  ? 75  SER B CA  1 
ATOM 3879 C C   . SER D 4 75  ? 354.046 370.839 481.668 1.00 47.13  ? 75  SER B C   1 
ATOM 3880 O O   . SER D 4 75  ? 354.781 371.794 481.416 1.00 47.13  ? 75  SER B O   1 
ATOM 3881 C CB  . SER D 4 75  ? 351.609 370.809 481.153 1.00 47.13  ? 75  SER B CB  1 
ATOM 3882 O OG  . SER D 4 75  ? 350.306 371.000 481.664 1.00 47.13  ? 75  SER B OG  1 
ATOM 3883 N N   . ALA D 4 76  ? 354.405 369.593 481.484 1.00 46.02  ? 76  ALA B N   1 
ATOM 3884 C CA  . ALA D 4 76  ? 355.731 369.318 480.956 1.00 46.02  ? 76  ALA B CA  1 
ATOM 3885 C C   . ALA D 4 76  ? 355.723 368.375 479.767 1.00 46.02  ? 76  ALA B C   1 
ATOM 3886 O O   . ALA D 4 76  ? 356.544 368.536 478.867 1.00 46.02  ? 76  ALA B O   1 
ATOM 3887 C CB  . ALA D 4 76  ? 356.623 368.755 482.061 1.00 46.02  ? 76  ALA B CB  1 
ATOM 3888 N N   . GLY D 4 77  ? 354.837 367.399 479.743 1.00 44.61  ? 77  GLY B N   1 
ATOM 3889 C CA  . GLY D 4 77  ? 354.802 366.449 478.648 1.00 44.61  ? 77  GLY B CA  1 
ATOM 3890 C C   . GLY D 4 77  ? 354.103 365.175 479.060 1.00 44.61  ? 77  GLY B C   1 
ATOM 3891 O O   . GLY D 4 77  ? 353.708 364.996 480.205 1.00 44.61  ? 77  GLY B O   1 
ATOM 3892 N N   . TRP D 4 78  ? 353.925 364.289 478.079 1.00 44.44  ? 78  TRP B N   1 
ATOM 3893 C CA  . TRP D 4 78  ? 353.301 362.986 478.280 1.00 44.44  ? 78  TRP B CA  1 
ATOM 3894 C C   . TRP D 4 78  ? 353.942 361.996 477.318 1.00 44.44  ? 78  TRP B C   1 
ATOM 3895 O O   . TRP D 4 78  ? 354.520 362.392 476.308 1.00 44.44  ? 78  TRP B O   1 
ATOM 3896 C CB  . TRP D 4 78  ? 351.782 363.038 478.049 1.00 44.44  ? 78  TRP B CB  1 
ATOM 3897 C CG  . TRP D 4 78  ? 351.058 364.070 478.864 1.00 44.44  ? 78  TRP B CG  1 
ATOM 3898 C CD1 . TRP D 4 78  ? 350.538 363.913 480.111 1.00 44.44  ? 78  TRP B CD1 1 
ATOM 3899 C CD2 . TRP D 4 78  ? 350.802 365.428 478.494 1.00 44.44  ? 78  TRP B CD2 1 
ATOM 3900 N NE1 . TRP D 4 78  ? 349.965 365.081 480.536 1.00 44.44  ? 78  TRP B NE1 1 
ATOM 3901 C CE2 . TRP D 4 78  ? 350.116 366.027 479.559 1.00 44.44  ? 78  TRP B CE2 1 
ATOM 3902 C CE3 . TRP D 4 78  ? 351.083 366.192 477.361 1.00 44.44  ? 78  TRP B CE3 1 
ATOM 3903 C CZ2 . TRP D 4 78  ? 349.712 367.349 479.527 1.00 44.44  ? 78  TRP B CZ2 1 
ATOM 3904 C CZ3 . TRP D 4 78  ? 350.679 367.500 477.333 1.00 44.44  ? 78  TRP B CZ3 1 
ATOM 3905 C CH2 . TRP D 4 78  ? 350.000 368.065 478.405 1.00 44.44  ? 78  TRP B CH2 1 
ATOM 3906 N N   . TRP D 4 79  ? 353.845 360.702 477.630 1.00 48.48  ? 79  TRP B N   1 
ATOM 3907 C CA  . TRP D 4 79  ? 354.282 359.687 476.678 1.00 48.48  ? 79  TRP B CA  1 
ATOM 3908 C C   . TRP D 4 79  ? 353.498 358.399 476.872 1.00 48.48  ? 79  TRP B C   1 
ATOM 3909 O O   . TRP D 4 79  ? 353.154 358.027 477.994 1.00 48.48  ? 79  TRP B O   1 
ATOM 3910 C CB  . TRP D 4 79  ? 355.795 359.401 476.760 1.00 48.48  ? 79  TRP B CB  1 
ATOM 3911 C CG  . TRP D 4 79  ? 356.277 358.458 477.837 1.00 48.48  ? 79  TRP B CG  1 
ATOM 3912 C CD1 . TRP D 4 79  ? 356.340 357.100 477.772 1.00 48.48  ? 79  TRP B CD1 1 
ATOM 3913 C CD2 . TRP D 4 79  ? 356.832 358.817 479.102 1.00 48.48  ? 79  TRP B CD2 1 
ATOM 3914 N NE1 . TRP D 4 79  ? 356.854 356.592 478.930 1.00 48.48  ? 79  TRP B NE1 1 
ATOM 3915 C CE2 . TRP D 4 79  ? 357.165 357.628 479.764 1.00 48.48  ? 79  TRP B CE2 1 
ATOM 3916 C CE3 . TRP D 4 79  ? 357.052 360.028 479.750 1.00 48.48  ? 79  TRP B CE3 1 
ATOM 3917 C CZ2 . TRP D 4 79  ? 357.714 357.615 481.029 1.00 48.48  ? 79  TRP B CZ2 1 
ATOM 3918 C CZ3 . TRP D 4 79  ? 357.593 360.012 481.006 1.00 48.48  ? 79  TRP B CZ3 1 
ATOM 3919 C CH2 . TRP D 4 79  ? 357.920 358.816 481.634 1.00 48.48  ? 79  TRP B CH2 1 
ATOM 3920 N N   . TRP D 4 80  ? 353.244 357.709 475.761 1.00 48.77  ? 80  TRP B N   1 
ATOM 3921 C CA  . TRP D 4 80  ? 352.562 356.421 475.746 1.00 48.77  ? 80  TRP B CA  1 
ATOM 3922 C C   . TRP D 4 80  ? 353.416 355.409 475.003 1.00 48.77  ? 80  TRP B C   1 
ATOM 3923 O O   . TRP D 4 80  ? 353.790 355.646 473.853 1.00 48.77  ? 80  TRP B O   1 
ATOM 3924 C CB  . TRP D 4 80  ? 351.200 356.501 475.052 1.00 48.77  ? 80  TRP B CB  1 
ATOM 3925 C CG  . TRP D 4 80  ? 350.208 357.403 475.675 1.00 48.77  ? 80  TRP B CG  1 
ATOM 3926 C CD1 . TRP D 4 80  ? 349.294 357.078 476.620 1.00 48.77  ? 80  TRP B CD1 1 
ATOM 3927 C CD2 . TRP D 4 80  ? 350.003 358.781 475.374 1.00 48.77  ? 80  TRP B CD2 1 
ATOM 3928 N NE1 . TRP D 4 80  ? 348.540 358.172 476.942 1.00 48.77  ? 80  TRP B NE1 1 
ATOM 3929 C CE2 . TRP D 4 80  ? 348.958 359.232 476.188 1.00 48.77  ? 80  TRP B CE2 1 
ATOM 3930 C CE3 . TRP D 4 80  ? 350.613 359.681 474.501 1.00 48.77  ? 80  TRP B CE3 1 
ATOM 3931 C CZ2 . TRP D 4 80  ? 348.505 360.539 476.155 1.00 48.77  ? 80  TRP B CZ2 1 
ATOM 3932 C CZ3 . TRP D 4 80  ? 350.163 360.977 474.471 1.00 48.77  ? 80  TRP B CZ3 1 
ATOM 3933 C CH2 . TRP D 4 80  ? 349.121 361.395 475.292 1.00 48.77  ? 80  TRP B CH2 1 
ATOM 3934 N N   . LYS D 4 81  ? 353.708 354.281 475.638 1.00 53.67  ? 81  LYS B N   1 
ATOM 3935 C CA  . LYS D 4 81  ? 354.354 353.179 474.941 1.00 53.67  ? 81  LYS B CA  1 
ATOM 3936 C C   . LYS D 4 81  ? 353.296 352.397 474.181 1.00 53.67  ? 81  LYS B C   1 
ATOM 3937 O O   . LYS D 4 81  ? 352.283 351.998 474.756 1.00 53.67  ? 81  LYS B O   1 
ATOM 3938 C CB  . LYS D 4 81  ? 355.090 352.278 475.924 1.00 53.67  ? 81  LYS B CB  1 
ATOM 3939 C CG  . LYS D 4 81  ? 356.141 352.997 476.726 1.00 53.67  ? 81  LYS B CG  1 
ATOM 3940 C CD  . LYS D 4 81  ? 357.443 353.043 475.988 1.00 53.67  ? 81  LYS B CD  1 
ATOM 3941 C CE  . LYS D 4 81  ? 358.540 353.561 476.875 1.00 53.67  ? 81  LYS B CE  1 
ATOM 3942 N NZ  . LYS D 4 81  ? 359.850 353.441 476.201 1.00 53.67  ? 81  LYS B NZ  1 
ATOM 3943 N N   . LEU D 4 82  ? 353.528 352.173 472.897 1.00 60.29  ? 82  LEU B N   1 
ATOM 3944 C CA  . LEU D 4 82  ? 352.378 351.967 472.026 1.00 60.29  ? 82  LEU B CA  1 
ATOM 3945 C C   . LEU D 4 82  ? 351.752 350.573 472.016 1.00 60.29  ? 82  LEU B C   1 
ATOM 3946 O O   . LEU D 4 82  ? 350.519 350.501 471.978 1.00 60.29  ? 82  LEU B O   1 
ATOM 3947 C CB  . LEU D 4 82  ? 352.711 352.391 470.597 1.00 60.29  ? 82  LEU B CB  1 
ATOM 3948 C CG  . LEU D 4 82  ? 351.485 352.807 469.782 1.00 60.29  ? 82  LEU B CG  1 
ATOM 3949 C CD1 . LEU D 4 82  ? 350.536 353.655 470.597 1.00 60.29  ? 82  LEU B CD1 1 
ATOM 3950 C CD2 . LEU D 4 82  ? 351.919 353.575 468.563 1.00 60.29  ? 82  LEU B CD2 1 
ATOM 3951 N N   . PRO D 4 83  ? 352.495 349.431 472.024 1.00 61.75  ? 83  PRO B N   1 
ATOM 3952 C CA  . PRO D 4 83  ? 351.779 348.160 472.226 1.00 61.75  ? 83  PRO B CA  1 
ATOM 3953 C C   . PRO D 4 83  ? 351.619 347.797 473.695 1.00 61.75  ? 83  PRO B C   1 
ATOM 3954 O O   . PRO D 4 83  ? 351.776 346.638 474.077 1.00 61.75  ? 83  PRO B O   1 
ATOM 3955 C CB  . PRO D 4 83  ? 352.653 347.147 471.485 1.00 61.75  ? 83  PRO B CB  1 
ATOM 3956 C CG  . PRO D 4 83  ? 353.997 347.671 471.640 1.00 61.75  ? 83  PRO B CG  1 
ATOM 3957 C CD  . PRO D 4 83  ? 353.896 349.173 471.634 1.00 61.75  ? 83  PRO B CD  1 
ATOM 3958 N N   . ASP D 4 84  ? 351.296 348.782 474.522 1.00 70.74  ? 84  ASP B N   1 
ATOM 3959 C CA  . ASP D 4 84  ? 351.062 348.585 475.942 1.00 70.74  ? 84  ASP B CA  1 
ATOM 3960 C C   . ASP D 4 84  ? 349.754 349.282 476.269 1.00 70.74  ? 84  ASP B C   1 
ATOM 3961 O O   . ASP D 4 84  ? 349.013 348.866 477.164 1.00 70.74  ? 84  ASP B O   1 
ATOM 3962 C CB  . ASP D 4 84  ? 352.221 349.161 476.757 1.00 70.74  ? 84  ASP B CB  1 
ATOM 3963 C CG  . ASP D 4 84  ? 352.312 348.590 478.162 1.00 70.74  ? 84  ASP B CG  1 
ATOM 3964 O OD1 . ASP D 4 84  ? 351.282 348.207 478.750 1.00 70.74  ? 84  ASP B OD1 1 
ATOM 3965 O OD2 . ASP D 4 84  ? 353.443 348.520 478.683 1.00 70.74  ? 84  ASP B OD2 1 
ATOM 3966 N N   . ALA D 4 85  ? 349.473 350.355 475.528 1.00 72.90  ? 85  ALA B N   1 
ATOM 3967 C CA  . ALA D 4 85  ? 348.222 351.079 475.695 1.00 72.90  ? 85  ALA B CA  1 
ATOM 3968 C C   . ALA D 4 85  ? 347.034 350.237 475.266 1.00 72.90  ? 85  ALA B C   1 
ATOM 3969 O O   . ALA D 4 85  ? 345.978 350.286 475.902 1.00 72.90  ? 85  ALA B O   1 
ATOM 3970 C CB  . ALA D 4 85  ? 348.262 352.381 474.900 1.00 72.90  ? 85  ALA B CB  1 
ATOM 3971 N N   . LEU D 4 86  ? 347.195 349.435 474.219 1.00 76.06  ? 86  LEU B N   1 
ATOM 3972 C CA  . LEU D 4 86  ? 346.129 348.576 473.731 1.00 76.06  ? 86  LEU B CA  1 
ATOM 3973 C C   . LEU D 4 86  ? 346.223 347.160 474.291 1.00 76.06  ? 86  LEU B C   1 
ATOM 3974 O O   . LEU D 4 86  ? 345.729 346.214 473.674 1.00 76.06  ? 86  LEU B O   1 
ATOM 3975 C CB  . LEU D 4 86  ? 346.138 348.550 472.207 1.00 76.06  ? 86  LEU B CB  1 
ATOM 3976 C CG  . LEU D 4 86  ? 346.384 349.884 471.513 1.00 76.06  ? 86  LEU B CG  1 
ATOM 3977 C CD1 . LEU D 4 86  ? 346.500 349.666 470.028 1.00 76.06  ? 86  LEU B CD1 1 
ATOM 3978 C CD2 . LEU D 4 86  ? 345.261 350.844 471.811 1.00 76.06  ? 86  LEU B CD2 1 
ATOM 3979 N N   . SER D 4 87  ? 346.851 346.995 475.454 1.00 82.27  ? 87  SER B N   1 
ATOM 3980 C CA  . SER D 4 87  ? 346.938 345.680 476.072 1.00 82.27  ? 87  SER B CA  1 
ATOM 3981 C C   . SER D 4 87  ? 345.651 345.282 476.766 1.00 82.27  ? 87  SER B C   1 
ATOM 3982 O O   . SER D 4 87  ? 345.319 344.095 476.795 1.00 82.27  ? 87  SER B O   1 
ATOM 3983 C CB  . SER D 4 87  ? 348.071 345.637 477.091 1.00 82.27  ? 87  SER B CB  1 
ATOM 3984 O OG  . SER D 4 87  ? 347.594 346.028 478.363 1.00 82.27  ? 87  SER B OG  1 
ATOM 3985 N N   . GLN D 4 88  ? 344.930 346.237 477.343 1.00 82.75  ? 88  GLN B N   1 
ATOM 3986 C CA  . GLN D 4 88  ? 343.656 345.952 477.985 1.00 82.75  ? 88  GLN B CA  1 
ATOM 3987 C C   . GLN D 4 88  ? 342.496 346.590 477.233 1.00 82.75  ? 88  GLN B C   1 
ATOM 3988 O O   . GLN D 4 88  ? 341.429 346.808 477.808 1.00 82.75  ? 88  GLN B O   1 
ATOM 3989 C CB  . GLN D 4 88  ? 343.695 346.410 479.442 1.00 82.75  ? 88  GLN B CB  1 
ATOM 3990 C CG  . GLN D 4 88  ? 344.836 345.764 480.220 1.00 82.75  ? 88  GLN B CG  1 
ATOM 3991 C CD  . GLN D 4 88  ? 345.301 346.584 481.410 1.00 82.75  ? 88  GLN B CD  1 
ATOM 3992 O OE1 . GLN D 4 88  ? 344.612 346.671 482.426 1.00 82.75  ? 88  GLN B OE1 1 
ATOM 3993 N NE2 . GLN D 4 88  ? 346.481 347.183 481.291 1.00 82.75  ? 88  GLN B NE2 1 
ATOM 3994 N N   . MET D 4 89  ? 342.684 346.873 475.948 1.00 84.98  ? 89  MET B N   1 
ATOM 3995 C CA  . MET D 4 89  ? 341.662 347.520 475.132 1.00 84.98  ? 89  MET B CA  1 
ATOM 3996 C C   . MET D 4 89  ? 340.827 346.479 474.388 1.00 84.98  ? 89  MET B C   1 
ATOM 3997 O O   . MET D 4 89  ? 340.777 346.434 473.161 1.00 84.98  ? 89  MET B O   1 
ATOM 3998 C CB  . MET D 4 89  ? 342.310 348.504 474.163 1.00 84.98  ? 89  MET B CB  1 
ATOM 3999 C CG  . MET D 4 89  ? 342.756 349.816 474.775 1.00 84.98  ? 89  MET B CG  1 
ATOM 4000 S SD  . MET D 4 89  ? 341.319 350.786 475.211 1.00 84.98  ? 89  MET B SD  1 
ATOM 4001 C CE  . MET D 4 89  ? 342.069 352.152 476.066 1.00 84.98  ? 89  MET B CE  1 
ATOM 4002 N N   . GLY D 4 90  ? 340.151 345.640 475.167 1.00 92.05  ? 90  GLY B N   1 
ATOM 4003 C CA  . GLY D 4 90  ? 339.094 344.794 474.642 1.00 92.05  ? 90  GLY B CA  1 
ATOM 4004 C C   . GLY D 4 90  ? 339.489 343.685 473.688 1.00 92.05  ? 90  GLY B C   1 
ATOM 4005 O O   . GLY D 4 90  ? 340.395 342.896 473.971 1.00 92.05  ? 90  GLY B O   1 
ATOM 4006 N N   . LEU D 4 91  ? 338.814 343.630 472.539 1.00 97.51  ? 91  LEU B N   1 
ATOM 4007 C CA  . LEU D 4 91  ? 338.933 342.504 471.622 1.00 97.51  ? 91  LEU B CA  1 
ATOM 4008 C C   . LEU D 4 91  ? 340.227 342.537 470.816 1.00 97.51  ? 91  LEU B C   1 
ATOM 4009 O O   . LEU D 4 91  ? 340.573 341.538 470.178 1.00 97.51  ? 91  LEU B O   1 
ATOM 4010 C CB  . LEU D 4 91  ? 337.712 342.476 470.695 1.00 97.51  ? 91  LEU B CB  1 
ATOM 4011 C CG  . LEU D 4 91  ? 337.343 341.239 469.873 1.00 97.51  ? 91  LEU B CG  1 
ATOM 4012 C CD1 . LEU D 4 91  ? 337.057 340.069 470.796 1.00 97.51  ? 91  LEU B CD1 1 
ATOM 4013 C CD2 . LEU D 4 91  ? 336.128 341.536 469.015 1.00 97.51  ? 91  LEU B CD2 1 
ATOM 4014 N N   . PHE D 4 92  ? 340.943 343.662 470.826 1.00 92.19  ? 92  PHE B N   1 
ATOM 4015 C CA  . PHE D 4 92  ? 342.354 343.654 470.455 1.00 92.19  ? 92  PHE B CA  1 
ATOM 4016 C C   . PHE D 4 92  ? 343.220 343.230 471.626 1.00 92.19  ? 92  PHE B C   1 
ATOM 4017 O O   . PHE D 4 92  ? 344.163 342.452 471.453 1.00 92.19  ? 92  PHE B O   1 
ATOM 4018 C CB  . PHE D 4 92  ? 342.784 345.038 469.977 1.00 92.19  ? 92  PHE B CB  1 
ATOM 4019 C CG  . PHE D 4 92  ? 344.208 345.111 469.521 1.00 92.19  ? 92  PHE B CG  1 
ATOM 4020 C CD1 . PHE D 4 92  ? 344.563 344.680 468.259 1.00 92.19  ? 92  PHE B CD1 1 
ATOM 4021 C CD2 . PHE D 4 92  ? 345.190 345.630 470.346 1.00 92.19  ? 92  PHE B CD2 1 
ATOM 4022 C CE1 . PHE D 4 92  ? 345.871 344.754 467.836 1.00 92.19  ? 92  PHE B CE1 1 
ATOM 4023 C CE2 . PHE D 4 92  ? 346.498 345.698 469.929 1.00 92.19  ? 92  PHE B CE2 1 
ATOM 4024 C CZ  . PHE D 4 92  ? 346.839 345.263 468.676 1.00 92.19  ? 92  PHE B CZ  1 
ATOM 4025 N N   . GLY D 4 93  ? 342.923 343.742 472.816 1.00 93.47  ? 93  GLY B N   1 
ATOM 4026 C CA  . GLY D 4 93  ? 343.683 343.429 474.004 1.00 93.47  ? 93  GLY B CA  1 
ATOM 4027 C C   . GLY D 4 93  ? 343.527 342.022 474.514 1.00 93.47  ? 93  GLY B C   1 
ATOM 4028 O O   . GLY D 4 93  ? 344.404 341.547 475.241 1.00 93.47  ? 93  GLY B O   1 
ATOM 4029 N N   . GLN D 4 94  ? 342.440 341.339 474.153 1.00 100.27 ? 94  GLN B N   1 
ATOM 4030 C CA  . GLN D 4 94  ? 342.291 339.928 474.492 1.00 100.27 ? 94  GLN B CA  1 
ATOM 4031 C C   . GLN D 4 94  ? 343.076 339.039 473.539 1.00 100.27 ? 94  GLN B C   1 
ATOM 4032 O O   . GLN D 4 94  ? 343.400 337.899 473.878 1.00 100.27 ? 94  GLN B O   1 
ATOM 4033 C CB  . GLN D 4 94  ? 340.812 339.529 474.490 1.00 100.27 ? 94  GLN B CB  1 
ATOM 4034 C CG  . GLN D 4 94  ? 340.075 339.740 475.821 1.00 100.27 ? 94  GLN B CG  1 
ATOM 4035 C CD  . GLN D 4 94  ? 340.325 338.634 476.844 1.00 100.27 ? 94  GLN B CD  1 
ATOM 4036 O OE1 . GLN D 4 94  ? 341.457 338.405 477.276 1.00 100.27 ? 94  GLN B OE1 1 
ATOM 4037 N NE2 . GLN D 4 94  ? 339.258 337.945 477.238 1.00 100.27 ? 94  GLN B NE2 1 
ATOM 4038 N N   . ASN D 4 95  ? 343.404 339.554 472.353 1.00 104.22 ? 95  ASN B N   1 
ATOM 4039 C CA  . ASN D 4 95  ? 344.259 338.833 471.421 1.00 104.22 ? 95  ASN B CA  1 
ATOM 4040 C C   . ASN D 4 95  ? 345.714 338.799 471.870 1.00 104.22 ? 95  ASN B C   1 
ATOM 4041 O O   . ASN D 4 95  ? 346.492 338.002 471.336 1.00 104.22 ? 95  ASN B O   1 
ATOM 4042 C CB  . ASN D 4 95  ? 344.167 339.464 470.033 1.00 104.22 ? 95  ASN B CB  1 
ATOM 4043 C CG  . ASN D 4 95  ? 343.054 338.874 469.195 1.00 104.22 ? 95  ASN B CG  1 
ATOM 4044 O OD1 . ASN D 4 95  ? 341.934 338.682 469.671 1.00 104.22 ? 95  ASN B OD1 1 
ATOM 4045 N ND2 . ASN D 4 95  ? 343.356 338.585 467.933 1.00 104.22 ? 95  ASN B ND2 1 
ATOM 4046 N N   . MET D 4 96  ? 346.098 339.651 472.827 1.00 103.44 ? 96  MET B N   1 
ATOM 4047 C CA  . MET D 4 96  ? 347.485 339.707 473.277 1.00 103.44 ? 96  MET B CA  1 
ATOM 4048 C C   . MET D 4 96  ? 347.898 338.459 474.038 1.00 103.44 ? 96  MET B C   1 
ATOM 4049 O O   . MET D 4 96  ? 349.051 338.031 473.934 1.00 103.44 ? 96  MET B O   1 
ATOM 4050 C CB  . MET D 4 96  ? 347.713 340.942 474.152 1.00 103.44 ? 96  MET B CB  1 
ATOM 4051 C CG  . MET D 4 96  ? 347.770 342.317 473.461 1.00 103.44 ? 96  MET B CG  1 
ATOM 4052 S SD  . MET D 4 96  ? 348.747 342.496 471.947 1.00 103.44 ? 96  MET B SD  1 
ATOM 4053 C CE  . MET D 4 96  ? 347.536 342.211 470.654 1.00 103.44 ? 96  MET B CE  1 
ATOM 4054 N N   . GLN D 4 97  ? 346.986 337.854 474.786 1.00 104.27 ? 97  GLN B N   1 
ATOM 4055 C CA  . GLN D 4 97  ? 347.362 336.710 475.604 1.00 104.27 ? 97  GLN B CA  1 
ATOM 4056 C C   . GLN D 4 97  ? 347.278 335.396 474.837 1.00 104.27 ? 97  GLN B C   1 
ATOM 4057 O O   . GLN D 4 97  ? 347.938 334.418 475.205 1.00 104.27 ? 97  GLN B O   1 
ATOM 4058 C CB  . GLN D 4 97  ? 346.486 336.658 476.857 1.00 104.27 ? 97  GLN B CB  1 
ATOM 4059 C CG  . GLN D 4 97  ? 346.636 337.885 477.738 1.00 104.27 ? 97  GLN B CG  1 
ATOM 4060 C CD  . GLN D 4 97  ? 347.434 337.618 478.996 1.00 104.27 ? 97  GLN B CD  1 
ATOM 4061 O OE1 . GLN D 4 97  ? 347.387 336.523 479.552 1.00 104.27 ? 97  GLN B OE1 1 
ATOM 4062 N NE2 . GLN D 4 97  ? 348.178 338.619 479.450 1.00 104.27 ? 97  GLN B NE2 1 
ATOM 4063 N N   . TYR D 4 98  ? 346.481 335.352 473.774 1.00 104.16 ? 98  TYR B N   1 
ATOM 4064 C CA  . TYR D 4 98  ? 346.340 334.125 473.004 1.00 104.16 ? 98  TYR B CA  1 
ATOM 4065 C C   . TYR D 4 98  ? 347.437 333.993 471.954 1.00 104.16 ? 98  TYR B C   1 
ATOM 4066 O O   . TYR D 4 98  ? 347.628 332.916 471.380 1.00 104.16 ? 98  TYR B O   1 
ATOM 4067 C CB  . TYR D 4 98  ? 344.961 334.080 472.348 1.00 104.16 ? 98  TYR B CB  1 
ATOM 4068 C CG  . TYR D 4 98  ? 343.838 333.754 473.307 1.00 104.16 ? 98  TYR B CG  1 
ATOM 4069 C CD1 . TYR D 4 98  ? 343.278 334.738 474.112 1.00 104.16 ? 98  TYR B CD1 1 
ATOM 4070 C CD2 . TYR D 4 98  ? 343.329 332.463 473.403 1.00 104.16 ? 98  TYR B CD2 1 
ATOM 4071 C CE1 . TYR D 4 98  ? 342.247 334.450 474.988 1.00 104.16 ? 98  TYR B CE1 1 
ATOM 4072 C CE2 . TYR D 4 98  ? 342.296 332.164 474.279 1.00 104.16 ? 98  TYR B CE2 1 
ATOM 4073 C CZ  . TYR D 4 98  ? 341.761 333.164 475.069 1.00 104.16 ? 98  TYR B CZ  1 
ATOM 4074 O OH  . TYR D 4 98  ? 340.736 332.883 475.943 1.00 104.16 ? 98  TYR B OH  1 
ATOM 4075 N N   . HIS D 4 99  ? 348.159 335.074 471.677 1.00 105.97 ? 99  HIS B N   1 
ATOM 4076 C CA  . HIS D 4 99  ? 349.157 335.072 470.616 1.00 105.97 ? 99  HIS B CA  1 
ATOM 4077 C C   . HIS D 4 99  ? 350.549 335.393 471.156 1.00 105.97 ? 99  HIS B C   1 
ATOM 4078 O O   . HIS D 4 99  ? 350.728 336.322 471.946 1.00 105.97 ? 99  HIS B O   1 
ATOM 4079 C CB  . HIS D 4 99  ? 348.767 336.080 469.538 1.00 105.97 ? 99  HIS B CB  1 
ATOM 4080 C CG  . HIS D 4 99  ? 347.392 335.869 468.984 1.00 105.97 ? 99  HIS B CG  1 
ATOM 4081 N ND1 . HIS D 4 99  ? 346.266 336.412 469.564 1.00 105.97 ? 99  HIS B ND1 1 
ATOM 4082 C CD2 . HIS D 4 99  ? 346.961 335.186 467.897 1.00 105.97 ? 99  HIS B CD2 1 
ATOM 4083 C CE1 . HIS D 4 99  ? 345.202 336.069 468.862 1.00 105.97 ? 99  HIS B CE1 1 
ATOM 4084 N NE2 . HIS D 4 99  ? 345.596 335.325 467.845 1.00 105.97 ? 99  HIS B NE2 1 
ATOM 4085 N N   . TYR D 4 100 ? 351.546 334.622 470.700 1.00 101.84 ? 100 TYR B N   1 
ATOM 4086 C CA  . TYR D 4 100 ? 352.921 334.796 471.175 1.00 101.84 ? 100 TYR B CA  1 
ATOM 4087 C C   . TYR D 4 100 ? 353.723 335.730 470.267 1.00 101.84 ? 100 TYR B C   1 
ATOM 4088 O O   . TYR D 4 100 ? 354.637 336.418 470.730 1.00 101.84 ? 100 TYR B O   1 
ATOM 4089 C CB  . TYR D 4 100 ? 353.618 333.433 471.293 1.00 101.84 ? 100 TYR B CB  1 
ATOM 4090 C CG  . TYR D 4 100 ? 354.845 333.409 472.202 1.00 101.84 ? 100 TYR B CG  1 
ATOM 4091 C CD1 . TYR D 4 100 ? 354.725 333.151 473.569 1.00 101.84 ? 100 TYR B CD1 1 
ATOM 4092 C CD2 . TYR D 4 100 ? 356.123 333.629 471.693 1.00 101.84 ? 100 TYR B CD2 1 
ATOM 4093 C CE1 . TYR D 4 100 ? 355.846 333.121 474.402 1.00 101.84 ? 100 TYR B CE1 1 
ATOM 4094 C CE2 . TYR D 4 100 ? 357.247 333.601 472.519 1.00 101.84 ? 100 TYR B CE2 1 
ATOM 4095 C CZ  . TYR D 4 100 ? 357.100 333.346 473.870 1.00 101.84 ? 100 TYR B CZ  1 
ATOM 4096 O OH  . TYR D 4 100 ? 358.204 333.316 474.691 1.00 101.84 ? 100 TYR B OH  1 
ATOM 4097 N N   . LEU D 4 101 ? 353.408 335.756 468.975 1.00 97.31  ? 101 LEU B N   1 
ATOM 4098 C CA  . LEU D 4 101 ? 354.105 336.590 468.007 1.00 97.31  ? 101 LEU B CA  1 
ATOM 4099 C C   . LEU D 4 101 ? 353.126 337.533 467.310 1.00 97.31  ? 101 LEU B C   1 
ATOM 4100 O O   . LEU D 4 101 ? 351.934 337.561 467.614 1.00 97.31  ? 101 LEU B O   1 
ATOM 4101 C CB  . LEU D 4 101 ? 354.850 335.720 466.989 1.00 97.31  ? 101 LEU B CB  1 
ATOM 4102 C CG  . LEU D 4 101 ? 355.625 334.520 467.529 1.00 97.31  ? 101 LEU B CG  1 
ATOM 4103 C CD1 . LEU D 4 101 ? 356.152 333.649 466.407 1.00 97.31  ? 101 LEU B CD1 1 
ATOM 4104 C CD2 . LEU D 4 101 ? 356.771 335.001 468.406 1.00 97.31  ? 101 LEU B CD2 1 
ATOM 4105 N N   . GLY D 4 102 ? 353.645 338.312 466.359 1.00 90.12  ? 102 GLY B N   1 
ATOM 4106 C CA  . GLY D 4 102 ? 352.824 339.218 465.575 1.00 90.12  ? 102 GLY B CA  1 
ATOM 4107 C C   . GLY D 4 102 ? 353.505 340.508 465.153 1.00 90.12  ? 102 GLY B C   1 
ATOM 4108 O O   . GLY D 4 102 ? 354.506 340.908 465.752 1.00 90.12  ? 102 GLY B O   1 
ATOM 4109 N N   . ARG D 4 103 ? 352.976 341.166 464.119 1.00 83.77  ? 103 ARG B N   1 
ATOM 4110 C CA  . ARG D 4 103 ? 353.470 342.459 463.671 1.00 83.77  ? 103 ARG B CA  1 
ATOM 4111 C C   . ARG D 4 103 ? 352.298 343.373 463.350 1.00 83.77  ? 103 ARG B C   1 
ATOM 4112 O O   . ARG D 4 103 ? 351.281 342.935 462.810 1.00 83.77  ? 103 ARG B O   1 
ATOM 4113 C CB  . ARG D 4 103 ? 354.374 342.332 462.448 1.00 83.77  ? 103 ARG B CB  1 
ATOM 4114 C CG  . ARG D 4 103 ? 353.846 341.437 461.363 1.00 83.77  ? 103 ARG B CG  1 
ATOM 4115 C CD  . ARG D 4 103 ? 354.791 341.411 460.175 1.00 83.77  ? 103 ARG B CD  1 
ATOM 4116 N NE  . ARG D 4 103 ? 354.571 342.540 459.277 1.00 83.77  ? 103 ARG B NE  1 
ATOM 4117 C CZ  . ARG D 4 103 ? 355.514 343.089 458.519 1.00 83.77  ? 103 ARG B CZ  1 
ATOM 4118 N NH1 . ARG D 4 103 ? 356.752 342.616 458.553 1.00 83.77  ? 103 ARG B NH1 1 
ATOM 4119 N NH2 . ARG D 4 103 ? 355.220 344.112 457.728 1.00 83.77  ? 103 ARG B NH2 1 
ATOM 4120 N N   . THR D 4 104 ? 352.442 344.651 463.691 1.00 77.50  ? 104 THR B N   1 
ATOM 4121 C CA  . THR D 4 104 ? 351.333 345.589 463.596 1.00 77.50  ? 104 THR B CA  1 
ATOM 4122 C C   . THR D 4 104 ? 351.833 346.949 463.127 1.00 77.50  ? 104 THR B C   1 
ATOM 4123 O O   . THR D 4 104 ? 352.973 347.329 463.398 1.00 77.50  ? 104 THR B O   1 
ATOM 4124 C CB  . THR D 4 104 ? 350.624 345.730 464.947 1.00 77.50  ? 104 THR B CB  1 
ATOM 4125 O OG1 . THR D 4 104 ? 351.593 345.645 465.999 1.00 77.50  ? 104 THR B OG1 1 
ATOM 4126 C CG2 . THR D 4 104 ? 349.572 344.658 465.142 1.00 77.50  ? 104 THR B CG2 1 
ATOM 4127 N N   . GLY D 4 105 ? 350.962 347.676 462.425 1.00 71.73  ? 105 GLY B N   1 
ATOM 4128 C CA  . GLY D 4 105 ? 351.173 349.070 462.107 1.00 71.73  ? 105 GLY B CA  1 
ATOM 4129 C C   . GLY D 4 105 ? 350.079 349.918 462.739 1.00 71.73  ? 105 GLY B C   1 
ATOM 4130 O O   . GLY D 4 105 ? 349.039 349.418 463.156 1.00 71.73  ? 105 GLY B O   1 
ATOM 4131 N N   . TYR D 4 106 ? 350.321 351.225 462.802 1.00 63.88  ? 106 TYR B N   1 
ATOM 4132 C CA  . TYR D 4 106 ? 349.425 352.097 463.548 1.00 63.88  ? 106 TYR B CA  1 
ATOM 4133 C C   . TYR D 4 106 ? 349.086 353.349 462.755 1.00 63.88  ? 106 TYR B C   1 
ATOM 4134 O O   . TYR D 4 106 ? 349.757 353.708 461.788 1.00 63.88  ? 106 TYR B O   1 
ATOM 4135 C CB  . TYR D 4 106 ? 350.026 352.490 464.895 1.00 63.88  ? 106 TYR B CB  1 
ATOM 4136 C CG  . TYR D 4 106 ? 350.334 351.318 465.778 1.00 63.88  ? 106 TYR B CG  1 
ATOM 4137 C CD1 . TYR D 4 106 ? 349.317 350.607 466.389 1.00 63.88  ? 106 TYR B CD1 1 
ATOM 4138 C CD2 . TYR D 4 106 ? 351.641 350.928 466.008 1.00 63.88  ? 106 TYR B CD2 1 
ATOM 4139 C CE1 . TYR D 4 106 ? 349.592 349.532 467.201 1.00 63.88  ? 106 TYR B CE1 1 
ATOM 4140 C CE2 . TYR D 4 106 ? 351.927 349.857 466.820 1.00 63.88  ? 106 TYR B CE2 1 
ATOM 4141 C CZ  . TYR D 4 106 ? 350.898 349.163 467.413 1.00 63.88  ? 106 TYR B CZ  1 
ATOM 4142 O OH  . TYR D 4 106 ? 351.175 348.093 468.225 1.00 63.88  ? 106 TYR B OH  1 
ATOM 4143 N N   . THR D 4 107 ? 348.012 354.008 463.192 1.00 59.11  ? 107 THR B N   1 
ATOM 4144 C CA  . THR D 4 107 ? 347.584 355.309 462.682 1.00 59.11  ? 107 THR B CA  1 
ATOM 4145 C C   . THR D 4 107 ? 347.063 356.103 463.870 1.00 59.11  ? 107 THR B C   1 
ATOM 4146 O O   . THR D 4 107 ? 346.132 355.662 464.547 1.00 59.11  ? 107 THR B O   1 
ATOM 4147 C CB  . THR D 4 107 ? 346.504 355.171 461.618 1.00 59.11  ? 107 THR B CB  1 
ATOM 4148 O OG1 . THR D 4 107 ? 346.862 354.127 460.714 1.00 59.11  ? 107 THR B OG1 1 
ATOM 4149 C CG2 . THR D 4 107 ? 346.364 356.457 460.850 1.00 59.11  ? 107 THR B CG2 1 
ATOM 4150 N N   . ILE D 4 108 ? 347.655 357.262 464.129 1.00 53.53  ? 108 ILE B N   1 
ATOM 4151 C CA  . ILE D 4 108 ? 347.403 358.025 465.345 1.00 53.53  ? 108 ILE B CA  1 
ATOM 4152 C C   . ILE D 4 108 ? 346.744 359.341 464.970 1.00 53.53  ? 108 ILE B C   1 
ATOM 4153 O O   . ILE D 4 108 ? 347.197 360.023 464.048 1.00 53.53  ? 108 ILE B O   1 
ATOM 4154 C CB  . ILE D 4 108 ? 348.704 358.265 466.128 1.00 53.53  ? 108 ILE B CB  1 
ATOM 4155 C CG1 . ILE D 4 108 ? 349.486 356.964 466.265 1.00 53.53  ? 108 ILE B CG1 1 
ATOM 4156 C CG2 . ILE D 4 108 ? 348.407 358.805 467.498 1.00 53.53  ? 108 ILE B CG2 1 
ATOM 4157 C CD1 . ILE D 4 108 ? 350.934 357.159 466.569 1.00 53.53  ? 108 ILE B CD1 1 
ATOM 4158 N N   . HIS D 4 109 ? 345.676 359.693 465.683 1.00 56.30  ? 109 HIS B N   1 
ATOM 4159 C CA  . HIS D 4 109 ? 344.985 360.971 465.537 1.00 56.30  ? 109 HIS B CA  1 
ATOM 4160 C C   . HIS D 4 109 ? 345.047 361.694 466.874 1.00 56.30  ? 109 HIS B C   1 
ATOM 4161 O O   . HIS D 4 109 ? 344.491 361.213 467.864 1.00 56.30  ? 109 HIS B O   1 
ATOM 4162 C CB  . HIS D 4 109 ? 343.531 360.775 465.120 1.00 56.30  ? 109 HIS B CB  1 
ATOM 4163 C CG  . HIS D 4 109 ? 343.353 360.289 463.718 1.00 56.30  ? 109 HIS B CG  1 
ATOM 4164 N ND1 . HIS D 4 109 ? 342.964 359.001 463.422 1.00 56.30  ? 109 HIS B ND1 1 
ATOM 4165 C CD2 . HIS D 4 109 ? 343.478 360.926 462.531 1.00 56.30  ? 109 HIS B CD2 1 
ATOM 4166 C CE1 . HIS D 4 109 ? 342.873 358.860 462.112 1.00 56.30  ? 109 HIS B CE1 1 
ATOM 4167 N NE2 . HIS D 4 109 ? 343.181 360.014 461.548 1.00 56.30  ? 109 HIS B NE2 1 
ATOM 4168 N N   . VAL D 4 110 ? 345.707 362.846 466.908 1.00 49.13  ? 110 VAL B N   1 
ATOM 4169 C CA  . VAL D 4 110 ? 345.807 363.671 468.107 1.00 49.13  ? 110 VAL B CA  1 
ATOM 4170 C C   . VAL D 4 110 ? 345.182 365.021 467.802 1.00 49.13  ? 110 VAL B C   1 
ATOM 4171 O O   . VAL D 4 110 ? 345.542 365.659 466.810 1.00 49.13  ? 110 VAL B O   1 
ATOM 4172 C CB  . VAL D 4 110 ? 347.267 363.834 468.556 1.00 49.13  ? 110 VAL B CB  1 
ATOM 4173 C CG1 . VAL D 4 110 ? 347.392 364.928 469.584 1.00 49.13  ? 110 VAL B CG1 1 
ATOM 4174 C CG2 . VAL D 4 110 ? 347.782 362.542 469.114 1.00 49.13  ? 110 VAL B CG2 1 
ATOM 4175 N N   . GLN D 4 111 ? 344.248 365.455 468.644 1.00 51.43  ? 111 GLN B N   1 
ATOM 4176 C CA  . GLN D 4 111 ? 343.598 366.742 468.445 1.00 51.43  ? 111 GLN B CA  1 
ATOM 4177 C C   . GLN D 4 111 ? 343.341 367.410 469.783 1.00 51.43  ? 111 GLN B C   1 
ATOM 4178 O O   . GLN D 4 111 ? 342.813 366.782 470.702 1.00 51.43  ? 111 GLN B O   1 
ATOM 4179 C CB  . GLN D 4 111 ? 342.287 366.572 467.688 1.00 51.43  ? 111 GLN B CB  1 
ATOM 4180 C CG  . GLN D 4 111 ? 341.582 365.290 468.022 1.00 51.43  ? 111 GLN B CG  1 
ATOM 4181 C CD  . GLN D 4 111 ? 340.317 365.111 467.231 1.00 51.43  ? 111 GLN B CD  1 
ATOM 4182 O OE1 . GLN D 4 111 ? 339.856 366.037 466.567 1.00 51.43  ? 111 GLN B OE1 1 
ATOM 4183 N NE2 . GLN D 4 111 ? 339.753 363.912 467.281 1.00 51.43  ? 111 GLN B NE2 1 
ATOM 4184 N N   . CYS D 4 112 ? 343.713 368.679 469.884 1.00 53.06  ? 112 CYS B N   1 
ATOM 4185 C CA  . CYS D 4 112 ? 343.399 369.504 471.037 1.00 53.06  ? 112 CYS B CA  1 
ATOM 4186 C C   . CYS D 4 112 ? 342.472 370.623 470.600 1.00 53.06  ? 112 CYS B C   1 
ATOM 4187 O O   . CYS D 4 112 ? 342.664 371.215 469.537 1.00 53.06  ? 112 CYS B O   1 
ATOM 4188 C CB  . CYS D 4 112 ? 344.663 370.080 471.668 1.00 53.06  ? 112 CYS B CB  1 
ATOM 4189 S SG  . CYS D 4 112 ? 345.728 370.968 470.540 1.00 53.06  ? 112 CYS B SG  1 
ATOM 4190 N N   . ASN D 4 113 ? 341.457 370.899 471.399 1.00 51.54  ? 113 ASN B N   1 
ATOM 4191 C CA  . ASN D 4 113 ? 340.411 371.836 471.011 1.00 51.54  ? 113 ASN B CA  1 
ATOM 4192 C C   . ASN D 4 113 ? 340.420 373.031 471.957 1.00 51.54  ? 113 ASN B C   1 
ATOM 4193 O O   . ASN D 4 113 ? 339.842 372.987 473.045 1.00 51.54  ? 113 ASN B O   1 
ATOM 4194 C CB  . ASN D 4 113 ? 339.057 371.139 470.981 1.00 51.54  ? 113 ASN B CB  1 
ATOM 4195 C CG  . ASN D 4 113 ? 338.871 370.201 472.133 1.00 51.54  ? 113 ASN B CG  1 
ATOM 4196 O OD1 . ASN D 4 113 ? 339.733 370.096 472.995 1.00 51.54  ? 113 ASN B OD1 1 
ATOM 4197 N ND2 . ASN D 4 113 ? 337.746 369.508 472.158 1.00 51.54  ? 113 ASN B ND2 1 
ATOM 4198 N N   . ALA D 4 114 ? 341.074 374.100 471.531 1.00 52.45  ? 114 ALA B N   1 
ATOM 4199 C CA  . ALA D 4 114 ? 341.070 375.359 472.246 1.00 52.45  ? 114 ALA B CA  1 
ATOM 4200 C C   . ALA D 4 114 ? 340.264 376.361 471.442 1.00 52.45  ? 114 ALA B C   1 
ATOM 4201 O O   . ALA D 4 114 ? 339.654 376.024 470.426 1.00 52.45  ? 114 ALA B O   1 
ATOM 4202 C CB  . ALA D 4 114 ? 342.489 375.880 472.475 1.00 52.45  ? 114 ALA B CB  1 
ATOM 4203 N N   . SER D 4 115 ? 340.257 377.600 471.910 1.00 51.17  ? 115 SER B N   1 
ATOM 4204 C CA  . SER D 4 115 ? 339.564 378.677 471.222 1.00 51.17  ? 115 SER B CA  1 
ATOM 4205 C C   . SER D 4 115 ? 340.558 379.471 470.384 1.00 51.17  ? 115 SER B C   1 
ATOM 4206 O O   . SER D 4 115 ? 341.707 379.069 470.188 1.00 51.17  ? 115 SER B O   1 
ATOM 4207 C CB  . SER D 4 115 ? 338.847 379.559 472.230 1.00 51.17  ? 115 SER B CB  1 
ATOM 4208 O OG  . SER D 4 115 ? 339.678 379.785 473.349 1.00 51.17  ? 115 SER B OG  1 
ATOM 4209 N N   . LYS D 4 116 ? 340.114 380.611 469.867 1.00 51.68  ? 116 LYS B N   1 
ATOM 4210 C CA  . LYS D 4 116 ? 340.994 381.605 469.274 1.00 51.68  ? 116 LYS B CA  1 
ATOM 4211 C C   . LYS D 4 116 ? 341.457 382.636 470.289 1.00 51.68  ? 116 LYS B C   1 
ATOM 4212 O O   . LYS D 4 116 ? 341.868 383.731 469.904 1.00 51.68  ? 116 LYS B O   1 
ATOM 4213 C CB  . LYS D 4 116 ? 340.298 382.307 468.110 1.00 51.68  ? 116 LYS B CB  1 
ATOM 4214 C CG  . LYS D 4 116 ? 339.987 381.404 466.937 1.00 51.68  ? 116 LYS B CG  1 
ATOM 4215 C CD  . LYS D 4 116 ? 341.250 380.977 466.215 1.00 51.68  ? 116 LYS B CD  1 
ATOM 4216 C CE  . LYS D 4 116 ? 341.008 379.732 465.380 1.00 51.68  ? 116 LYS B CE  1 
ATOM 4217 N NZ  . LYS D 4 116 ? 342.212 378.860 465.296 1.00 51.68  ? 116 LYS B NZ  1 
ATOM 4218 N N   . PHE D 4 117 ? 341.379 382.316 471.573 1.00 49.01  ? 117 PHE B N   1 
ATOM 4219 C CA  . PHE D 4 117 ? 341.860 383.183 472.628 1.00 49.01  ? 117 PHE B CA  1 
ATOM 4220 C C   . PHE D 4 117 ? 343.001 382.556 473.416 1.00 49.01  ? 117 PHE B C   1 
ATOM 4221 O O   . PHE D 4 117 ? 343.635 383.250 474.216 1.00 49.01  ? 117 PHE B O   1 
ATOM 4222 C CB  . PHE D 4 117 ? 340.707 383.546 473.576 1.00 49.01  ? 117 PHE B CB  1 
ATOM 4223 C CG  . PHE D 4 117 ? 339.777 384.606 473.039 1.00 49.01  ? 117 PHE B CG  1 
ATOM 4224 C CD1 . PHE D 4 117 ? 338.902 384.333 472.006 1.00 49.01  ? 117 PHE B CD1 1 
ATOM 4225 C CD2 . PHE D 4 117 ? 339.765 385.872 473.588 1.00 49.01  ? 117 PHE B CD2 1 
ATOM 4226 C CE1 . PHE D 4 117 ? 338.048 385.309 471.522 1.00 49.01  ? 117 PHE B CE1 1 
ATOM 4227 C CE2 . PHE D 4 117 ? 338.912 386.847 473.106 1.00 49.01  ? 117 PHE B CE2 1 
ATOM 4228 C CZ  . PHE D 4 117 ? 338.057 386.562 472.075 1.00 49.01  ? 117 PHE B CZ  1 
ATOM 4229 N N   . HIS D 4 118 ? 343.269 381.270 473.216 1.00 49.09  ? 118 HIS B N   1 
ATOM 4230 C CA  . HIS D 4 118 ? 344.396 380.566 473.805 1.00 49.09  ? 118 HIS B CA  1 
ATOM 4231 C C   . HIS D 4 118 ? 345.590 380.604 472.860 1.00 49.09  ? 118 HIS B C   1 
ATOM 4232 O O   . HIS D 4 118 ? 345.477 380.987 471.696 1.00 49.09  ? 118 HIS B O   1 
ATOM 4233 C CB  . HIS D 4 118 ? 344.033 379.113 474.102 1.00 49.09  ? 118 HIS B CB  1 
ATOM 4234 C CG  . HIS D 4 118 ? 342.986 378.944 475.154 1.00 49.09  ? 118 HIS B CG  1 
ATOM 4235 N ND1 . HIS D 4 118 ? 341.639 378.921 474.869 1.00 49.09  ? 118 HIS B ND1 1 
ATOM 4236 C CD2 . HIS D 4 118 ? 343.089 378.764 476.491 1.00 49.09  ? 118 HIS B CD2 1 
ATOM 4237 C CE1 . HIS D 4 118 ? 340.958 378.744 475.985 1.00 49.09  ? 118 HIS B CE1 1 
ATOM 4238 N NE2 . HIS D 4 118 ? 341.815 378.644 476.984 1.00 49.09  ? 118 HIS B NE2 1 
ATOM 4239 N N   . GLN D 4 119 ? 346.741 380.177 473.370 1.00 48.55  ? 119 GLN B N   1 
ATOM 4240 C CA  . GLN D 4 119 ? 347.955 380.165 472.571 1.00 48.55  ? 119 GLN B CA  1 
ATOM 4241 C C   . GLN D 4 119 ? 348.898 379.091 473.090 1.00 48.55  ? 119 GLN B C   1 
ATOM 4242 O O   . GLN D 4 119 ? 348.925 378.795 474.285 1.00 48.55  ? 119 GLN B O   1 
ATOM 4243 C CB  . GLN D 4 119 ? 348.632 381.529 472.599 1.00 48.55  ? 119 GLN B CB  1 
ATOM 4244 C CG  . GLN D 4 119 ? 348.780 382.090 473.983 1.00 48.55  ? 119 GLN B CG  1 
ATOM 4245 C CD  . GLN D 4 119 ? 349.327 383.490 473.978 1.00 48.55  ? 119 GLN B CD  1 
ATOM 4246 O OE1 . GLN D 4 119 ? 350.516 383.704 474.190 1.00 48.55  ? 119 GLN B OE1 1 
ATOM 4247 N NE2 . GLN D 4 119 ? 348.461 384.458 473.740 1.00 48.55  ? 119 GLN B NE2 1 
ATOM 4248 N N   . GLY D 4 120 ? 349.671 378.511 472.182 1.00 45.75  ? 120 GLY B N   1 
ATOM 4249 C CA  . GLY D 4 120 ? 350.577 377.443 472.551 1.00 45.75  ? 120 GLY B CA  1 
ATOM 4250 C C   . GLY D 4 120 ? 351.138 376.766 471.322 1.00 45.75  ? 120 GLY B C   1 
ATOM 4251 O O   . GLY D 4 120 ? 350.874 377.168 470.189 1.00 45.75  ? 120 GLY B O   1 
ATOM 4252 N N   . CYS D 4 121 ? 351.923 375.719 471.574 1.00 43.83  ? 121 CYS B N   1 
ATOM 4253 C CA  . CYS D 4 121 ? 352.571 374.959 470.514 1.00 43.83  ? 121 CYS B CA  1 
ATOM 4254 C C   . CYS D 4 121 ? 353.010 373.609 471.054 1.00 43.83  ? 121 CYS B C   1 
ATOM 4255 O O   . CYS D 4 121 ? 353.727 373.543 472.051 1.00 43.83  ? 121 CYS B O   1 
ATOM 4256 C CB  . CYS D 4 121 ? 353.783 375.698 469.953 1.00 43.83  ? 121 CYS B CB  1 
ATOM 4257 S SG  . CYS D 4 121 ? 354.264 375.165 468.308 1.00 43.83  ? 121 CYS B SG  1 
ATOM 4258 N N   . LEU D 4 122 ? 352.598 372.540 470.381 1.00 41.80  ? 122 LEU B N   1 
ATOM 4259 C CA  . LEU D 4 122 ? 352.954 371.187 470.767 1.00 41.80  ? 122 LEU B CA  1 
ATOM 4260 C C   . LEU D 4 122 ? 353.860 370.562 469.718 1.00 41.80  ? 122 LEU B C   1 
ATOM 4261 O O   . LEU D 4 122 ? 353.908 371.001 468.569 1.00 41.80  ? 122 LEU B O   1 
ATOM 4262 C CB  . LEU D 4 122 ? 351.717 370.308 470.929 1.00 41.80  ? 122 LEU B CB  1 
ATOM 4263 C CG  . LEU D 4 122 ? 350.798 370.490 472.123 1.00 41.80  ? 122 LEU B CG  1 
ATOM 4264 C CD1 . LEU D 4 122 ? 349.690 369.491 472.028 1.00 41.80  ? 122 LEU B CD1 1 
ATOM 4265 C CD2 . LEU D 4 122 ? 351.550 370.275 473.382 1.00 41.80  ? 122 LEU B CD2 1 
ATOM 4266 N N   . LEU D 4 123 ? 354.565 369.514 470.125 1.00 42.51  ? 123 LEU B N   1 
ATOM 4267 C CA  . LEU D 4 123 ? 355.315 368.661 469.218 1.00 42.51  ? 123 LEU B CA  1 
ATOM 4268 C C   . LEU D 4 123 ? 354.882 367.228 469.456 1.00 42.51  ? 123 LEU B C   1 
ATOM 4269 O O   . LEU D 4 123 ? 354.923 366.751 470.592 1.00 42.51  ? 123 LEU B O   1 
ATOM 4270 C CB  . LEU D 4 123 ? 356.815 368.799 469.435 1.00 42.51  ? 123 LEU B CB  1 
ATOM 4271 C CG  . LEU D 4 123 ? 357.689 367.793 468.697 1.00 42.51  ? 123 LEU B CG  1 
ATOM 4272 C CD1 . LEU D 4 123 ? 357.539 367.955 467.208 1.00 42.51  ? 123 LEU B CD1 1 
ATOM 4273 C CD2 . LEU D 4 123 ? 359.131 367.965 469.097 1.00 42.51  ? 123 LEU B CD2 1 
ATOM 4274 N N   . VAL D 4 124 ? 354.468 366.548 468.397 1.00 42.62  ? 124 VAL B N   1 
ATOM 4275 C CA  . VAL D 4 124 ? 353.893 365.208 468.488 1.00 42.62  ? 124 VAL B CA  1 
ATOM 4276 C C   . VAL D 4 124 ? 354.831 364.272 467.736 1.00 42.62  ? 124 VAL B C   1 
ATOM 4277 O O   . VAL D 4 124 ? 354.727 364.114 466.521 1.00 42.62  ? 124 VAL B O   1 
ATOM 4278 C CB  . VAL D 4 124 ? 352.476 365.155 467.920 1.00 42.62  ? 124 VAL B CB  1 
ATOM 4279 C CG1 . VAL D 4 124 ? 351.862 363.800 468.150 1.00 42.62  ? 124 VAL B CG1 1 
ATOM 4280 C CG2 . VAL D 4 124 ? 351.625 366.224 468.549 1.00 42.62  ? 124 VAL B CG2 1 
ATOM 4281 N N   . VAL D 4 125 ? 355.750 363.637 468.450 1.00 44.23  ? 125 VAL B N   1 
ATOM 4282 C CA  . VAL D 4 125 ? 356.742 362.776 467.839 1.00 44.23  ? 125 VAL B CA  1 
ATOM 4283 C C   . VAL D 4 125 ? 356.359 361.319 468.059 1.00 44.23  ? 125 VAL B C   1 
ATOM 4284 O O   . VAL D 4 125 ? 355.563 360.989 468.931 1.00 44.23  ? 125 VAL B O   1 
ATOM 4285 C CB  . VAL D 4 125 ? 358.155 363.055 468.382 1.00 44.23  ? 125 VAL B CB  1 
ATOM 4286 C CG1 . VAL D 4 125 ? 358.746 364.249 467.718 1.00 44.23  ? 125 VAL B CG1 1 
ATOM 4287 C CG2 . VAL D 4 125 ? 358.083 363.300 469.850 1.00 44.23  ? 125 VAL B CG2 1 
ATOM 4288 N N   . CYS D 4 126 ? 356.949 360.427 467.265 1.00 49.18  ? 126 CYS B N   1 
ATOM 4289 C CA  . CYS D 4 126 ? 356.716 358.990 467.404 1.00 49.18  ? 126 CYS B CA  1 
ATOM 4290 C C   . CYS D 4 126 ? 358.055 358.276 467.249 1.00 49.18  ? 126 CYS B C   1 
ATOM 4291 O O   . CYS D 4 126 ? 358.524 358.070 466.129 1.00 49.18  ? 126 CYS B O   1 
ATOM 4292 C CB  . CYS D 4 126 ? 355.706 358.499 466.384 1.00 49.18  ? 126 CYS B CB  1 
ATOM 4293 S SG  . CYS D 4 126 ? 355.445 356.733 466.467 1.00 49.18  ? 126 CYS B SG  1 
ATOM 4294 N N   . VAL D 4 127 ? 358.642 357.871 468.368 1.00 48.06  ? 127 VAL B N   1 
ATOM 4295 C CA  . VAL D 4 127 ? 360.041 357.457 468.438 1.00 48.06  ? 127 VAL B CA  1 
ATOM 4296 C C   . VAL D 4 127 ? 360.112 355.937 468.352 1.00 48.06  ? 127 VAL B C   1 
ATOM 4297 O O   . VAL D 4 127 ? 359.556 355.258 469.223 1.00 48.06  ? 127 VAL B O   1 
ATOM 4298 C CB  . VAL D 4 127 ? 360.692 357.948 469.733 1.00 48.06  ? 127 VAL B CB  1 
ATOM 4299 C CG1 . VAL D 4 127 ? 362.175 357.743 469.671 1.00 48.06  ? 127 VAL B CG1 1 
ATOM 4300 C CG2 . VAL D 4 127 ? 360.355 359.393 469.963 1.00 48.06  ? 127 VAL B CG2 1 
ATOM 4301 N N   . PRO D 4 128 ? 360.783 355.366 467.351 1.00 47.79  ? 128 PRO B N   1 
ATOM 4302 C CA  . PRO D 4 128 ? 361.007 353.915 467.347 1.00 47.79  ? 128 PRO B CA  1 
ATOM 4303 C C   . PRO D 4 128 ? 362.166 353.531 468.254 1.00 47.79  ? 128 PRO B C   1 
ATOM 4304 O O   . PRO D 4 128 ? 363.259 354.090 468.149 1.00 47.79  ? 128 PRO B O   1 
ATOM 4305 C CB  . PRO D 4 128 ? 361.324 353.608 465.881 1.00 47.79  ? 128 PRO B CB  1 
ATOM 4306 C CG  . PRO D 4 128 ? 361.809 354.869 465.333 1.00 47.79  ? 128 PRO B CG  1 
ATOM 4307 C CD  . PRO D 4 128 ? 361.098 355.966 466.049 1.00 47.79  ? 128 PRO B CD  1 
ATOM 4308 N N   . GLU D 4 129 ? 361.912 352.553 469.133 1.00 53.24  ? 129 GLU B N   1 
ATOM 4309 C CA  . GLU D 4 129 ? 362.876 351.995 470.089 1.00 53.24  ? 129 GLU B CA  1 
ATOM 4310 C C   . GLU D 4 129 ? 363.454 353.078 471.000 1.00 53.24  ? 129 GLU B C   1 
ATOM 4311 O O   . GLU D 4 129 ? 364.646 353.377 470.982 1.00 53.24  ? 129 GLU B O   1 
ATOM 4312 C CB  . GLU D 4 129 ? 363.990 351.219 469.379 1.00 53.24  ? 129 GLU B CB  1 
ATOM 4313 C CG  . GLU D 4 129 ? 363.515 350.317 468.257 1.00 53.24  ? 129 GLU B CG  1 
ATOM 4314 C CD  . GLU D 4 129 ? 363.263 348.893 468.701 1.00 53.24  ? 129 GLU B CD  1 
ATOM 4315 O OE1 . GLU D 4 129 ? 363.125 348.658 469.916 1.00 53.24  ? 129 GLU B OE1 1 
ATOM 4316 O OE2 . GLU D 4 129 ? 363.207 348.001 467.833 1.00 53.24  ? 129 GLU B OE2 1 
ATOM 4317 N N   . ALA D 4 130 ? 362.572 353.673 471.798 1.00 51.58  ? 130 ALA B N   1 
ATOM 4318 C CA  . ALA D 4 130 ? 362.957 354.748 472.707 1.00 51.58  ? 130 ALA B CA  1 
ATOM 4319 C C   . ALA D 4 130 ? 363.292 354.155 474.068 1.00 51.58  ? 130 ALA B C   1 
ATOM 4320 O O   . ALA D 4 130 ? 362.437 353.991 474.937 1.00 51.58  ? 130 ALA B O   1 
ATOM 4321 C CB  . ALA D 4 130 ? 361.846 355.780 472.817 1.00 51.58  ? 130 ALA B CB  1 
ATOM 4322 N N   . GLU D 4 131 ? 364.564 353.823 474.253 1.00 54.60  ? 131 GLU B N   1 
ATOM 4323 C CA  . GLU D 4 131 ? 365.027 353.389 475.560 1.00 54.60  ? 131 GLU B CA  1 
ATOM 4324 C C   . GLU D 4 131 ? 365.042 354.574 476.507 1.00 54.60  ? 131 GLU B C   1 
ATOM 4325 O O   . GLU D 4 131 ? 365.572 355.636 476.175 1.00 54.60  ? 131 GLU B O   1 
ATOM 4326 C CB  . GLU D 4 131 ? 366.423 352.783 475.485 1.00 54.60  ? 131 GLU B CB  1 
ATOM 4327 C CG  . GLU D 4 131 ? 366.522 351.484 474.747 1.00 54.60  ? 131 GLU B CG  1 
ATOM 4328 C CD  . GLU D 4 131 ? 367.920 350.912 474.814 1.00 54.60  ? 131 GLU B CD  1 
ATOM 4329 O OE1 . GLU D 4 131 ? 368.792 351.551 475.434 1.00 54.60  ? 131 GLU B OE1 1 
ATOM 4330 O OE2 . GLU D 4 131 ? 368.158 349.839 474.227 1.00 54.60  ? 131 GLU B OE2 1 
ATOM 4331 N N   . MET D 4 132 ? 364.462 354.395 477.682 1.00 54.59  ? 132 MET B N   1 
ATOM 4332 C CA  . MET D 4 132 ? 364.442 355.428 478.698 1.00 54.59  ? 132 MET B CA  1 
ATOM 4333 C C   . MET D 4 132 ? 365.639 355.250 479.617 1.00 54.59  ? 132 MET B C   1 
ATOM 4334 O O   . MET D 4 132 ? 366.270 354.196 479.651 1.00 54.59  ? 132 MET B O   1 
ATOM 4335 C CB  . MET D 4 132 ? 363.130 355.384 479.486 1.00 54.59  ? 132 MET B CB  1 
ATOM 4336 C CG  . MET D 4 132 ? 361.866 355.365 478.628 1.00 54.59  ? 132 MET B CG  1 
ATOM 4337 S SD  . MET D 4 132 ? 361.715 356.701 477.436 1.00 54.59  ? 132 MET B SD  1 
ATOM 4338 C CE  . MET D 4 132 ? 361.373 358.081 478.506 1.00 54.59  ? 132 MET B CE  1 
ATOM 4339 N N   . GLY D 4 133 ? 365.957 356.300 480.365 1.00 55.42  ? 133 GLY B N   1 
ATOM 4340 C CA  . GLY D 4 133 ? 367.110 356.308 481.245 1.00 55.42  ? 133 GLY B CA  1 
ATOM 4341 C C   . GLY D 4 133 ? 366.698 356.408 482.701 1.00 55.42  ? 133 GLY B C   1 
ATOM 4342 O O   . GLY D 4 133 ? 365.833 357.206 483.059 1.00 55.42  ? 133 GLY B O   1 
ATOM 4343 N N   . CYS D 4 134 ? 367.336 355.604 483.543 1.00 58.08  ? 134 CYS B N   1 
ATOM 4344 C CA  . CYS D 4 134 ? 366.964 355.543 484.945 1.00 58.08  ? 134 CYS B CA  1 
ATOM 4345 C C   . CYS D 4 134 ? 367.513 356.744 485.704 1.00 58.08  ? 134 CYS B C   1 
ATOM 4346 O O   . CYS D 4 134 ? 368.335 357.513 485.203 1.00 58.08  ? 134 CYS B O   1 
ATOM 4347 C CB  . CYS D 4 134 ? 367.471 354.255 485.579 1.00 58.08  ? 134 CYS B CB  1 
ATOM 4348 S SG  . CYS D 4 134 ? 367.186 354.146 487.347 1.00 58.08  ? 134 CYS B SG  1 
ATOM 4349 N N   . SER D 4 135 ? 367.043 356.900 486.942 1.00 58.65  ? 135 SER B N   1 
ATOM 4350 C CA  . SER D 4 135 ? 367.533 357.981 487.786 1.00 58.65  ? 135 SER B CA  1 
ATOM 4351 C C   . SER D 4 135 ? 368.774 357.576 488.562 1.00 58.65  ? 135 SER B C   1 
ATOM 4352 O O   . SER D 4 135 ? 369.644 358.414 488.811 1.00 58.65  ? 135 SER B O   1 
ATOM 4353 C CB  . SER D 4 135 ? 366.447 358.431 488.751 1.00 58.65  ? 135 SER B CB  1 
ATOM 4354 O OG  . SER D 4 135 ? 366.499 357.662 489.929 1.00 58.65  ? 135 SER B OG  1 
ATOM 4355 N N   . ASN D 4 136 ? 368.867 356.315 488.966 1.00 60.89  ? 136 ASN B N   1 
ATOM 4356 C CA  . ASN D 4 136 ? 370.094 355.772 489.522 1.00 60.89  ? 136 ASN B CA  1 
ATOM 4357 C C   . ASN D 4 136 ? 370.961 355.265 488.387 1.00 60.89  ? 136 ASN B C   1 
ATOM 4358 O O   . ASN D 4 136 ? 370.463 354.654 487.441 1.00 60.89  ? 136 ASN B O   1 
ATOM 4359 C CB  . ASN D 4 136 ? 369.800 354.637 490.497 1.00 60.89  ? 136 ASN B CB  1 
ATOM 4360 C CG  . ASN D 4 136 ? 371.019 354.216 491.274 1.00 60.89  ? 136 ASN B CG  1 
ATOM 4361 O OD1 . ASN D 4 136 ? 371.973 354.977 491.403 1.00 60.89  ? 136 ASN B OD1 1 
ATOM 4362 N ND2 . ASN D 4 136 ? 370.998 353.000 491.802 1.00 60.89  ? 136 ASN B ND2 1 
ATOM 4363 N N   . LEU D 4 137 ? 372.260 355.512 488.483 1.00 59.07  ? 137 LEU B N   1 
ATOM 4364 C CA  . LEU D 4 137 ? 373.141 355.226 487.361 1.00 59.07  ? 137 LEU B CA  1 
ATOM 4365 C C   . LEU D 4 137 ? 373.453 353.748 487.198 1.00 59.07  ? 137 LEU B C   1 
ATOM 4366 O O   . LEU D 4 137 ? 374.022 353.370 486.171 1.00 59.07  ? 137 LEU B O   1 
ATOM 4367 C CB  . LEU D 4 137 ? 374.453 356.003 487.495 1.00 59.07  ? 137 LEU B CB  1 
ATOM 4368 C CG  . LEU D 4 137 ? 374.547 357.419 486.922 1.00 59.07  ? 137 LEU B CG  1 
ATOM 4369 C CD1 . LEU D 4 137 ? 374.227 357.385 485.461 1.00 59.07  ? 137 LEU B CD1 1 
ATOM 4370 C CD2 . LEU D 4 137 ? 373.673 358.409 487.624 1.00 59.07  ? 137 LEU B CD2 1 
ATOM 4371 N N   . ASN D 4 138 ? 373.095 352.904 488.166 1.00 62.92  ? 138 ASN B N   1 
ATOM 4372 C CA  . ASN D 4 138 ? 373.443 351.494 488.112 1.00 62.92  ? 138 ASN B CA  1 
ATOM 4373 C C   . ASN D 4 138 ? 372.279 350.571 487.799 1.00 62.92  ? 138 ASN B C   1 
ATOM 4374 O O   . ASN D 4 138 ? 372.504 349.499 487.235 1.00 62.92  ? 138 ASN B O   1 
ATOM 4375 C CB  . ASN D 4 138 ? 374.062 351.047 489.438 1.00 62.92  ? 138 ASN B CB  1 
ATOM 4376 C CG  . ASN D 4 138 ? 375.558 351.043 489.394 1.00 62.92  ? 138 ASN B CG  1 
ATOM 4377 O OD1 . ASN D 4 138 ? 376.158 350.204 488.728 1.00 62.92  ? 138 ASN B OD1 1 
ATOM 4378 N ND2 . ASN D 4 138 ? 376.179 351.979 490.098 1.00 62.92  ? 138 ASN B ND2 1 
ATOM 4379 N N   . ASN D 4 139 ? 371.061 350.947 488.147 1.00 62.08  ? 139 ASN B N   1 
ATOM 4380 C CA  . ASN D 4 139 ? 369.901 350.102 487.942 1.00 62.08  ? 139 ASN B CA  1 
ATOM 4381 C C   . ASN D 4 139 ? 369.280 350.393 486.586 1.00 62.08  ? 139 ASN B C   1 
ATOM 4382 O O   . ASN D 4 139 ? 369.835 351.112 485.757 1.00 62.08  ? 139 ASN B O   1 
ATOM 4383 C CB  . ASN D 4 139 ? 368.880 350.310 489.057 1.00 62.08  ? 139 ASN B CB  1 
ATOM 4384 C CG  . ASN D 4 139 ? 369.481 350.155 490.426 1.00 62.08  ? 139 ASN B CG  1 
ATOM 4385 O OD1 . ASN D 4 139 ? 370.521 349.524 490.589 1.00 62.08  ? 139 ASN B OD1 1 
ATOM 4386 N ND2 . ASN D 4 139 ? 368.834 350.738 491.425 1.00 62.08  ? 139 ASN B ND2 1 
ATOM 4387 N N   . THR D 4 140 ? 368.114 349.803 486.368 1.00 61.37  ? 140 THR B N   1 
ATOM 4388 C CA  . THR D 4 140 ? 367.283 350.001 485.200 1.00 61.37  ? 140 THR B CA  1 
ATOM 4389 C C   . THR D 4 140 ? 365.843 350.137 485.674 1.00 61.37  ? 140 THR B C   1 
ATOM 4390 O O   . THR D 4 140 ? 365.467 349.495 486.660 1.00 61.37  ? 140 THR B O   1 
ATOM 4391 C CB  . THR D 4 140 ? 367.425 348.828 484.226 1.00 61.37  ? 140 THR B CB  1 
ATOM 4392 O OG1 . THR D 4 140 ? 367.487 347.603 484.962 1.00 61.37  ? 140 THR B OG1 1 
ATOM 4393 C CG2 . THR D 4 140 ? 368.679 348.979 483.392 1.00 61.37  ? 140 THR B CG2 1 
ATOM 4394 N N   . PRO D 4 141 ? 365.025 350.966 485.025 1.00 60.51  ? 141 PRO B N   1 
ATOM 4395 C CA  . PRO D 4 141 ? 363.715 351.299 485.593 1.00 60.51  ? 141 PRO B CA  1 
ATOM 4396 C C   . PRO D 4 141 ? 362.728 350.144 485.545 1.00 60.51  ? 141 PRO B C   1 
ATOM 4397 O O   . PRO D 4 141 ? 362.721 349.337 484.615 1.00 60.51  ? 141 PRO B O   1 
ATOM 4398 C CB  . PRO D 4 141 ? 363.241 352.462 484.719 1.00 60.51  ? 141 PRO B CB  1 
ATOM 4399 C CG  . PRO D 4 141 ? 364.005 352.338 483.476 1.00 60.51  ? 141 PRO B CG  1 
ATOM 4400 C CD  . PRO D 4 141 ? 365.321 351.779 483.836 1.00 60.51  ? 141 PRO B CD  1 
ATOM 4401 N N   . GLU D 4 142 ? 361.886 350.077 486.573 1.00 66.15  ? 142 GLU B N   1 
ATOM 4402 C CA  . GLU D 4 142 ? 360.929 348.993 486.718 1.00 66.15  ? 142 GLU B CA  1 
ATOM 4403 C C   . GLU D 4 142 ? 359.772 349.168 485.742 1.00 66.15  ? 142 GLU B C   1 
ATOM 4404 O O   . GLU D 4 142 ? 359.577 350.234 485.161 1.00 66.15  ? 142 GLU B O   1 
ATOM 4405 C CB  . GLU D 4 142 ? 360.411 348.927 488.149 1.00 66.15  ? 142 GLU B CB  1 
ATOM 4406 C CG  . GLU D 4 142 ? 359.340 349.938 488.452 1.00 66.15  ? 142 GLU B CG  1 
ATOM 4407 C CD  . GLU D 4 142 ? 358.822 349.833 489.869 1.00 66.15  ? 142 GLU B CD  1 
ATOM 4408 O OE1 . GLU D 4 142 ? 359.623 350.003 490.810 1.00 66.15  ? 142 GLU B OE1 1 
ATOM 4409 O OE2 . GLU D 4 142 ? 357.611 349.576 490.041 1.00 66.15  ? 142 GLU B OE2 1 
ATOM 4410 N N   . PHE D 4 143 ? 358.987 348.100 485.580 1.00 64.10  ? 143 PHE B N   1 
ATOM 4411 C CA  . PHE D 4 143 ? 357.986 348.054 484.518 1.00 64.10  ? 143 PHE B CA  1 
ATOM 4412 C C   . PHE D 4 143 ? 356.837 349.019 484.759 1.00 64.10  ? 143 PHE B C   1 
ATOM 4413 O O   . PHE D 4 143 ? 356.280 349.561 483.801 1.00 64.10  ? 143 PHE B O   1 
ATOM 4414 C CB  . PHE D 4 143 ? 357.448 346.635 484.369 1.00 64.10  ? 143 PHE B CB  1 
ATOM 4415 C CG  . PHE D 4 143 ? 356.331 346.510 483.376 1.00 64.10  ? 143 PHE B CG  1 
ATOM 4416 C CD1 . PHE D 4 143 ? 356.581 346.611 482.024 1.00 64.10  ? 143 PHE B CD1 1 
ATOM 4417 C CD2 . PHE D 4 143 ? 355.032 346.291 483.798 1.00 64.10  ? 143 PHE B CD2 1 
ATOM 4418 C CE1 . PHE D 4 143 ? 355.565 346.495 481.108 1.00 64.10  ? 143 PHE B CE1 1 
ATOM 4419 C CE2 . PHE D 4 143 ? 354.008 346.178 482.886 1.00 64.10  ? 143 PHE B CE2 1 
ATOM 4420 C CZ  . PHE D 4 143 ? 354.277 346.279 481.538 1.00 64.10  ? 143 PHE B CZ  1 
ATOM 4421 N N   . SER D 4 144 ? 356.477 349.260 486.015 1.00 63.75  ? 144 SER B N   1 
ATOM 4422 C CA  . SER D 4 144 ? 355.363 350.149 486.314 1.00 63.75  ? 144 SER B CA  1 
ATOM 4423 C C   . SER D 4 144 ? 355.687 351.612 486.063 1.00 63.75  ? 144 SER B C   1 
ATOM 4424 O O   . SER D 4 144 ? 354.766 352.432 486.027 1.00 63.75  ? 144 SER B O   1 
ATOM 4425 C CB  . SER D 4 144 ? 354.922 349.968 487.766 1.00 63.75  ? 144 SER B CB  1 
ATOM 4426 O OG  . SER D 4 144 ? 355.923 350.405 488.665 1.00 63.75  ? 144 SER B OG  1 
ATOM 4427 N N   . GLU D 4 145 ? 356.961 351.959 485.894 1.00 63.70  ? 145 GLU B N   1 
ATOM 4428 C CA  . GLU D 4 145 ? 357.354 353.319 485.571 1.00 63.70  ? 145 GLU B CA  1 
ATOM 4429 C C   . GLU D 4 145 ? 357.524 353.549 484.083 1.00 63.70  ? 145 GLU B C   1 
ATOM 4430 O O   . GLU D 4 145 ? 357.448 354.697 483.642 1.00 63.70  ? 145 GLU B O   1 
ATOM 4431 C CB  . GLU D 4 145 ? 358.662 353.678 486.276 1.00 63.70  ? 145 GLU B CB  1 
ATOM 4432 C CG  . GLU D 4 145 ? 358.620 353.501 487.773 1.00 63.70  ? 145 GLU B CG  1 
ATOM 4433 C CD  . GLU D 4 145 ? 357.982 354.671 488.478 1.00 63.70  ? 145 GLU B CD  1 
ATOM 4434 O OE1 . GLU D 4 145 ? 357.876 355.747 487.862 1.00 63.70  ? 145 GLU B OE1 1 
ATOM 4435 O OE2 . GLU D 4 145 ? 357.591 354.516 489.651 1.00 63.70  ? 145 GLU B OE2 1 
ATOM 4436 N N   . LEU D 4 146 ? 357.767 352.496 483.307 1.00 60.65  ? 146 LEU B N   1 
ATOM 4437 C CA  . LEU D 4 146 ? 357.884 352.653 481.864 1.00 60.65  ? 146 LEU B CA  1 
ATOM 4438 C C   . LEU D 4 146 ? 356.551 353.003 481.228 1.00 60.65  ? 146 LEU B C   1 
ATOM 4439 O O   . LEU D 4 146 ? 356.472 353.940 480.430 1.00 60.65  ? 146 LEU B O   1 
ATOM 4440 C CB  . LEU D 4 146 ? 358.430 351.382 481.222 1.00 60.65  ? 146 LEU B CB  1 
ATOM 4441 C CG  . LEU D 4 146 ? 359.930 351.217 481.004 1.00 60.65  ? 146 LEU B CG  1 
ATOM 4442 C CD1 . LEU D 4 146 ? 360.419 352.301 480.095 1.00 60.65  ? 146 LEU B CD1 1 
ATOM 4443 C CD2 . LEU D 4 146 ? 360.704 351.229 482.275 1.00 60.65  ? 146 LEU B CD2 1 
ATOM 4444 N N   . SER D 4 147 ? 355.496 352.273 481.569 1.00 65.08  ? 147 SER B N   1 
ATOM 4445 C CA  . SER D 4 147 ? 354.219 352.463 480.902 1.00 65.08  ? 147 SER B CA  1 
ATOM 4446 C C   . SER D 4 147 ? 353.086 351.979 481.785 1.00 65.08  ? 147 SER B C   1 
ATOM 4447 O O   . SER D 4 147 ? 353.162 350.892 482.363 1.00 65.08  ? 147 SER B O   1 
ATOM 4448 C CB  . SER D 4 147 ? 354.187 351.712 479.574 1.00 65.08  ? 147 SER B CB  1 
ATOM 4449 O OG  . SER D 4 147 ? 354.440 350.336 479.777 1.00 65.08  ? 147 SER B OG  1 
ATOM 4450 N N   . GLY D 4 148 ? 352.046 352.792 481.882 1.00 66.21  ? 148 GLY B N   1 
ATOM 4451 C CA  . GLY D 4 148 ? 350.789 352.345 482.428 1.00 66.21  ? 148 GLY B CA  1 
ATOM 4452 C C   . GLY D 4 148 ? 349.813 352.024 481.313 1.00 66.21  ? 148 GLY B C   1 
ATOM 4453 O O   . GLY D 4 148 ? 349.906 352.556 480.213 1.00 66.21  ? 148 GLY B O   1 
ATOM 4454 N N   . GLY D 4 149 ? 348.883 351.120 481.606 1.00 73.01  ? 149 GLY B N   1 
ATOM 4455 C CA  . GLY D 4 149 ? 347.842 350.792 480.655 1.00 73.01  ? 149 GLY B CA  1 
ATOM 4456 C C   . GLY D 4 149 ? 346.889 351.955 480.499 1.00 73.01  ? 149 GLY B C   1 
ATOM 4457 O O   . GLY D 4 149 ? 346.264 352.387 481.483 1.00 73.01  ? 149 GLY B O   1 
ATOM 4458 N N   . ASP D 4 150 ? 346.789 352.494 479.278 1.00 73.62  ? 150 ASP B N   1 
ATOM 4459 C CA  . ASP D 4 150 ? 345.992 353.649 478.852 1.00 73.62  ? 150 ASP B CA  1 
ATOM 4460 C C   . ASP D 4 150 ? 346.046 354.854 479.789 1.00 73.62  ? 150 ASP B C   1 
ATOM 4461 O O   . ASP D 4 150 ? 345.105 355.646 479.861 1.00 73.62  ? 150 ASP B O   1 
ATOM 4462 C CB  . ASP D 4 150 ? 344.536 353.215 478.576 1.00 73.62  ? 150 ASP B CB  1 
ATOM 4463 C CG  . ASP D 4 150 ? 343.757 352.810 479.828 1.00 73.62  ? 150 ASP B CG  1 
ATOM 4464 O OD1 . ASP D 4 150 ? 343.197 353.683 480.526 1.00 73.62  ? 150 ASP B OD1 1 
ATOM 4465 O OD2 . ASP D 4 150 ? 343.702 351.593 480.111 1.00 73.62  ? 150 ASP B OD2 1 
ATOM 4466 N N   . SER D 4 151 ? 347.183 355.046 480.445 1.00 63.29  ? 151 SER B N   1 
ATOM 4467 C CA  . SER D 4 151 ? 347.425 356.221 481.261 1.00 63.29  ? 151 SER B CA  1 
ATOM 4468 C C   . SER D 4 151 ? 348.706 356.862 480.770 1.00 63.29  ? 151 SER B C   1 
ATOM 4469 O O   . SER D 4 151 ? 349.671 356.166 480.453 1.00 63.29  ? 151 SER B O   1 
ATOM 4470 C CB  . SER D 4 151 ? 347.541 355.878 482.744 1.00 63.29  ? 151 SER B CB  1 
ATOM 4471 O OG  . SER D 4 151 ? 346.504 355.004 483.137 1.00 63.29  ? 151 SER B OG  1 
ATOM 4472 N N   . ALA D 4 152 ? 348.704 358.181 480.685 1.00 55.39  ? 152 ALA B N   1 
ATOM 4473 C CA  . ALA D 4 152 ? 349.876 358.897 480.225 1.00 55.39  ? 152 ALA B CA  1 
ATOM 4474 C C   . ALA D 4 152 ? 350.838 359.094 481.381 1.00 55.39  ? 152 ALA B C   1 
ATOM 4475 O O   . ALA D 4 152 ? 350.487 359.708 482.392 1.00 55.39  ? 152 ALA B O   1 
ATOM 4476 C CB  . ALA D 4 152 ? 349.476 360.244 479.633 1.00 55.39  ? 152 ALA B CB  1 
ATOM 4477 N N   . ARG D 4 153 ? 352.039 358.547 481.250 1.00 56.02  ? 153 ARG B N   1 
ATOM 4478 C CA  . ARG D 4 153 ? 353.114 358.924 482.144 1.00 56.02  ? 153 ARG B CA  1 
ATOM 4479 C C   . ARG D 4 153 ? 353.640 360.281 481.717 1.00 56.02  ? 153 ARG B C   1 
ATOM 4480 O O   . ARG D 4 153 ? 353.787 360.560 480.528 1.00 56.02  ? 153 ARG B O   1 
ATOM 4481 C CB  . ARG D 4 153 ? 354.230 357.890 482.114 1.00 56.02  ? 153 ARG B CB  1 
ATOM 4482 C CG  . ARG D 4 153 ? 353.825 356.549 482.643 1.00 56.02  ? 153 ARG B CG  1 
ATOM 4483 C CD  . ARG D 4 153 ? 353.623 356.613 484.129 1.00 56.02  ? 153 ARG B CD  1 
ATOM 4484 N NE  . ARG D 4 153 ? 353.422 355.292 484.706 1.00 56.02  ? 153 ARG B NE  1 
ATOM 4485 C CZ  . ARG D 4 153 ? 352.249 354.675 484.773 1.00 56.02  ? 153 ARG B CZ  1 
ATOM 4486 N NH1 . ARG D 4 153 ? 352.166 353.474 485.321 1.00 56.02  ? 153 ARG B NH1 1 
ATOM 4487 N NH2 . ARG D 4 153 ? 351.159 355.254 484.296 1.00 56.02  ? 153 ARG B NH2 1 
ATOM 4488 N N   . MET D 4 154 ? 353.921 361.133 482.689 1.00 51.72  ? 154 MET B N   1 
ATOM 4489 C CA  . MET D 4 154 ? 354.157 362.533 482.389 1.00 51.72  ? 154 MET B CA  1 
ATOM 4490 C C   . MET D 4 154 ? 355.562 362.949 482.789 1.00 51.72  ? 154 MET B C   1 
ATOM 4491 O O   . MET D 4 154 ? 356.075 362.545 483.832 1.00 51.72  ? 154 MET B O   1 
ATOM 4492 C CB  . MET D 4 154 ? 353.116 363.420 483.078 1.00 51.72  ? 154 MET B CB  1 
ATOM 4493 C CG  . MET D 4 154 ? 352.878 363.095 484.532 1.00 51.72  ? 154 MET B CG  1 
ATOM 4494 S SD  . MET D 4 154 ? 351.483 364.015 485.200 1.00 51.72  ? 154 MET B SD  1 
ATOM 4495 C CE  . MET D 4 154 ? 350.125 363.176 484.400 1.00 51.72  ? 154 MET B CE  1 
ATOM 4496 N N   . PHE D 4 155 ? 356.167 363.784 481.946 1.00 48.08  ? 155 PHE B N   1 
ATOM 4497 C CA  . PHE D 4 155 ? 357.494 364.331 482.161 1.00 48.08  ? 155 PHE B CA  1 
ATOM 4498 C C   . PHE D 4 155 ? 357.497 365.300 483.338 1.00 48.08  ? 155 PHE B C   1 
ATOM 4499 O O   . PHE D 4 155 ? 356.467 365.605 483.940 1.00 48.08  ? 155 PHE B O   1 
ATOM 4500 C CB  . PHE D 4 155 ? 357.987 365.059 480.918 1.00 48.08  ? 155 PHE B CB  1 
ATOM 4501 C CG  . PHE D 4 155 ? 358.555 364.165 479.863 1.00 48.08  ? 155 PHE B CG  1 
ATOM 4502 C CD1 . PHE D 4 155 ? 359.737 363.489 480.070 1.00 48.08  ? 155 PHE B CD1 1 
ATOM 4503 C CD2 . PHE D 4 155 ? 357.925 364.038 478.642 1.00 48.08  ? 155 PHE B CD2 1 
ATOM 4504 C CE1 . PHE D 4 155 ? 360.264 362.682 479.084 1.00 48.08  ? 155 PHE B CE1 1 
ATOM 4505 C CE2 . PHE D 4 155 ? 358.444 363.235 477.658 1.00 48.08  ? 155 PHE B CE2 1 
ATOM 4506 C CZ  . PHE D 4 155 ? 359.612 362.558 477.878 1.00 48.08  ? 155 PHE B CZ  1 
ATOM 4507 N N   . THR D 4 156 ? 358.681 365.803 483.660 1.00 53.60  ? 156 THR B N   1 
ATOM 4508 C CA  . THR D 4 156 ? 358.857 366.681 484.802 1.00 53.60  ? 156 THR B CA  1 
ATOM 4509 C C   . THR D 4 156 ? 359.810 367.795 484.387 1.00 53.60  ? 156 THR B C   1 
ATOM 4510 O O   . THR D 4 156 ? 360.624 367.635 483.478 1.00 53.60  ? 156 THR B O   1 
ATOM 4511 C CB  . THR D 4 156 ? 359.390 365.890 486.013 1.00 53.60  ? 156 THR B CB  1 
ATOM 4512 O OG1 . THR D 4 156 ? 358.644 364.679 486.150 1.00 53.60  ? 156 THR B OG1 1 
ATOM 4513 C CG2 . THR D 4 156 ? 359.189 366.651 487.305 1.00 53.60  ? 156 THR B CG2 1 
ATOM 4514 N N   . ASP D 4 157 ? 359.686 368.953 485.025 1.00 58.68  ? 157 ASP B N   1 
ATOM 4515 C CA  . ASP D 4 157 ? 360.583 370.066 484.771 1.00 58.68  ? 157 ASP B CA  1 
ATOM 4516 C C   . ASP D 4 157 ? 361.729 370.149 485.767 1.00 58.68  ? 157 ASP B C   1 
ATOM 4517 O O   . ASP D 4 157 ? 362.293 371.229 485.952 1.00 58.68  ? 157 ASP B O   1 
ATOM 4518 C CB  . ASP D 4 157 ? 359.792 371.373 484.739 1.00 58.68  ? 157 ASP B CB  1 
ATOM 4519 C CG  . ASP D 4 157 ? 358.874 371.550 485.938 1.00 58.68  ? 157 ASP B CG  1 
ATOM 4520 O OD1 . ASP D 4 157 ? 359.253 371.223 487.081 1.00 58.68  ? 157 ASP B OD1 1 
ATOM 4521 O OD2 . ASP D 4 157 ? 357.744 372.041 485.729 1.00 58.68  ? 157 ASP B OD2 1 
ATOM 4522 N N   . THR D 4 158 ? 362.065 369.051 486.435 1.00 58.99  ? 158 THR B N   1 
ATOM 4523 C CA  . THR D 4 158 ? 363.177 369.008 487.371 1.00 58.99  ? 158 THR B CA  1 
ATOM 4524 C C   . THR D 4 158 ? 363.991 367.749 487.119 1.00 58.99  ? 158 THR B C   1 
ATOM 4525 O O   . THR D 4 158 ? 363.709 366.968 486.210 1.00 58.99  ? 158 THR B O   1 
ATOM 4526 C CB  . THR D 4 158 ? 362.705 369.029 488.832 1.00 58.99  ? 158 THR B CB  1 
ATOM 4527 O OG1 . THR D 4 158 ? 361.685 368.044 489.024 1.00 58.99  ? 158 THR B OG1 1 
ATOM 4528 C CG2 . THR D 4 158 ? 362.174 370.391 489.228 1.00 58.99  ? 158 THR B CG2 1 
ATOM 4529 N N   . GLN D 4 159 ? 365.010 367.557 487.943 1.00 61.14  ? 159 GLN B N   1 
ATOM 4530 C CA  . GLN D 4 159 ? 365.730 366.300 488.002 1.00 61.14  ? 159 GLN B CA  1 
ATOM 4531 C C   . GLN D 4 159 ? 365.110 365.394 489.051 1.00 61.14  ? 159 GLN B C   1 
ATOM 4532 O O   . GLN D 4 159 ? 364.702 365.843 490.124 1.00 61.14  ? 159 GLN B O   1 
ATOM 4533 C CB  . GLN D 4 159 ? 367.197 366.524 488.353 1.00 61.14  ? 159 GLN B CB  1 
ATOM 4534 C CG  . GLN D 4 159 ? 368.039 367.086 487.258 1.00 61.14  ? 159 GLN B CG  1 
ATOM 4535 C CD  . GLN D 4 159 ? 369.496 366.790 487.482 1.00 61.14  ? 159 GLN B CD  1 
ATOM 4536 O OE1 . GLN D 4 159 ? 370.367 367.489 486.975 1.00 61.14  ? 159 GLN B OE1 1 
ATOM 4537 N NE2 . GLN D 4 159 ? 369.775 365.746 488.249 1.00 61.14  ? 159 GLN B NE2 1 
ATOM 4538 N N   . VAL D 4 160 ? 365.055 364.108 488.740 1.00 59.38  ? 160 VAL B N   1 
ATOM 4539 C CA  . VAL D 4 160 ? 364.746 363.084 489.724 1.00 59.38  ? 160 VAL B CA  1 
ATOM 4540 C C   . VAL D 4 160 ? 366.056 362.677 490.377 1.00 59.38  ? 160 VAL B C   1 
ATOM 4541 O O   . VAL D 4 160 ? 367.013 362.316 489.682 1.00 59.38  ? 160 VAL B O   1 
ATOM 4542 C CB  . VAL D 4 160 ? 364.045 361.883 489.075 1.00 59.38  ? 160 VAL B CB  1 
ATOM 4543 C CG1 . VAL D 4 160 ? 363.827 360.803 490.091 1.00 59.38  ? 160 VAL B CG1 1 
ATOM 4544 C CG2 . VAL D 4 160 ? 362.730 362.310 488.481 1.00 59.38  ? 160 VAL B CG2 1 
ATOM 4545 N N   . GLY D 4 161 ? 366.113 362.762 491.704 1.00 65.88  ? 161 GLY B N   1 
ATOM 4546 C CA  . GLY D 4 161 ? 367.363 362.558 492.405 1.00 65.88  ? 161 GLY B CA  1 
ATOM 4547 C C   . GLY D 4 161 ? 367.834 361.120 492.362 1.00 65.88  ? 161 GLY B C   1 
ATOM 4548 O O   . GLY D 4 161 ? 367.074 360.190 492.104 1.00 65.88  ? 161 GLY B O   1 
ATOM 4549 N N   . GLU D 4 162 ? 369.124 360.933 492.625 1.00 68.67  ? 162 GLU B N   1 
ATOM 4550 C CA  . GLU D 4 162 ? 369.711 359.611 492.473 1.00 68.67  ? 162 GLU B CA  1 
ATOM 4551 C C   . GLU D 4 162 ? 369.442 358.702 493.659 1.00 68.67  ? 162 GLU B C   1 
ATOM 4552 O O   . GLU D 4 162 ? 369.824 357.530 493.615 1.00 68.67  ? 162 GLU B O   1 
ATOM 4553 C CB  . GLU D 4 162 ? 371.215 359.731 492.242 1.00 68.67  ? 162 GLU B CB  1 
ATOM 4554 C CG  . GLU D 4 162 ? 371.569 360.855 491.293 1.00 68.67  ? 162 GLU B CG  1 
ATOM 4555 C CD  . GLU D 4 162 ? 372.722 360.534 490.378 1.00 68.67  ? 162 GLU B CD  1 
ATOM 4556 O OE1 . GLU D 4 162 ? 372.768 361.118 489.277 1.00 68.67  ? 162 GLU B OE1 1 
ATOM 4557 O OE2 . GLU D 4 162 ? 373.574 359.702 490.749 1.00 68.67  ? 162 GLU B OE2 1 
ATOM 4558 N N   . SER D 4 163 ? 368.793 359.206 494.710 1.00 71.19  ? 163 SER B N   1 
ATOM 4559 C CA  . SER D 4 163 ? 368.400 358.343 495.815 1.00 71.19  ? 163 SER B CA  1 
ATOM 4560 C C   . SER D 4 163 ? 367.200 357.484 495.448 1.00 71.19  ? 163 SER B C   1 
ATOM 4561 O O   . SER D 4 163 ? 366.912 356.499 496.135 1.00 71.19  ? 163 SER B O   1 
ATOM 4562 C CB  . SER D 4 163 ? 368.080 359.175 497.049 1.00 71.19  ? 163 SER B CB  1 
ATOM 4563 O OG  . SER D 4 163 ? 366.718 359.549 497.043 1.00 71.19  ? 163 SER B OG  1 
ATOM 4564 N N   . ASN D 4 164 ? 366.485 357.846 494.389 1.00 66.60  ? 164 ASN B N   1 
ATOM 4565 C CA  . ASN D 4 164 ? 365.413 357.004 493.885 1.00 66.60  ? 164 ASN B CA  1 
ATOM 4566 C C   . ASN D 4 164 ? 365.999 355.785 493.186 1.00 66.60  ? 164 ASN B C   1 
ATOM 4567 O O   . ASN D 4 164 ? 366.887 355.912 492.340 1.00 66.60  ? 164 ASN B O   1 
ATOM 4568 C CB  . ASN D 4 164 ? 364.533 357.800 492.935 1.00 66.60  ? 164 ASN B CB  1 
ATOM 4569 C CG  . ASN D 4 164 ? 363.801 358.906 493.635 1.00 66.60  ? 164 ASN B CG  1 
ATOM 4570 O OD1 . ASN D 4 164 ? 364.010 360.081 493.352 1.00 66.60  ? 164 ASN B OD1 1 
ATOM 4571 N ND2 . ASN D 4 164 ? 362.943 358.538 494.575 1.00 66.60  ? 164 ASN B ND2 1 
ATOM 4572 N N   . ALA D 4 165 ? 365.501 354.602 493.540 1.00 67.18  ? 165 ALA B N   1 
ATOM 4573 C CA  . ALA D 4 165 ? 366.136 353.373 493.082 1.00 67.18  ? 165 ALA B CA  1 
ATOM 4574 C C   . ALA D 4 165 ? 365.800 353.075 491.628 1.00 67.18  ? 165 ALA B C   1 
ATOM 4575 O O   . ALA D 4 165 ? 366.684 353.069 490.768 1.00 67.18  ? 165 ALA B O   1 
ATOM 4576 C CB  . ALA D 4 165 ? 365.722 352.203 493.976 1.00 67.18  ? 165 ALA B CB  1 
ATOM 4577 N N   . LYS D 4 166 ? 364.528 352.825 491.333 1.00 64.31  ? 166 LYS B N   1 
ATOM 4578 C CA  . LYS D 4 166 ? 364.092 352.466 489.985 1.00 64.31  ? 166 LYS B CA  1 
ATOM 4579 C C   . LYS D 4 166 ? 363.007 353.446 489.562 1.00 64.31  ? 166 LYS B C   1 
ATOM 4580 O O   . LYS D 4 166 ? 361.817 353.177 489.723 1.00 64.31  ? 166 LYS B O   1 
ATOM 4581 C CB  . LYS D 4 166 ? 363.585 351.029 489.923 1.00 64.31  ? 166 LYS B CB  1 
ATOM 4582 C CG  . LYS D 4 166 ? 364.252 350.070 490.882 1.00 64.31  ? 166 LYS B CG  1 
ATOM 4583 C CD  . LYS D 4 166 ? 363.743 348.664 490.690 1.00 64.31  ? 166 LYS B CD  1 
ATOM 4584 C CE  . LYS D 4 166 ? 364.208 348.106 489.366 1.00 64.31  ? 166 LYS B CE  1 
ATOM 4585 N NZ  . LYS D 4 166 ? 365.686 348.208 489.217 1.00 64.31  ? 166 LYS B NZ  1 
ATOM 4586 N N   . LYS D 4 167 ? 363.422 354.583 489.019 1.00 59.67  ? 167 LYS B N   1 
ATOM 4587 C CA  . LYS D 4 167 ? 362.512 355.569 488.464 1.00 59.67  ? 167 LYS B CA  1 
ATOM 4588 C C   . LYS D 4 167 ? 363.116 356.106 487.180 1.00 59.67  ? 167 LYS B C   1 
ATOM 4589 O O   . LYS D 4 167 ? 364.338 356.174 487.038 1.00 59.67  ? 167 LYS B O   1 
ATOM 4590 C CB  . LYS D 4 167 ? 362.249 356.728 489.431 1.00 59.67  ? 167 LYS B CB  1 
ATOM 4591 C CG  . LYS D 4 167 ? 361.398 356.376 490.625 1.00 59.67  ? 167 LYS B CG  1 
ATOM 4592 C CD  . LYS D 4 167 ? 361.109 357.592 491.474 1.00 59.67  ? 167 LYS B CD  1 
ATOM 4593 C CE  . LYS D 4 167 ? 360.060 358.475 490.832 1.00 59.67  ? 167 LYS B CE  1 
ATOM 4594 N NZ  . LYS D 4 167 ? 359.606 359.557 491.750 1.00 59.67  ? 167 LYS B NZ  1 
ATOM 4595 N N   . VAL D 4 168 ? 362.255 356.489 486.243 1.00 55.52  ? 168 VAL B N   1 
ATOM 4596 C CA  . VAL D 4 168 ? 362.741 357.048 484.993 1.00 55.52  ? 168 VAL B CA  1 
ATOM 4597 C C   . VAL D 4 168 ? 363.134 358.498 485.216 1.00 55.52  ? 168 VAL B C   1 
ATOM 4598 O O   . VAL D 4 168 ? 362.377 359.277 485.807 1.00 55.52  ? 168 VAL B O   1 
ATOM 4599 C CB  . VAL D 4 168 ? 361.678 356.921 483.896 1.00 55.52  ? 168 VAL B CB  1 
ATOM 4600 C CG1 . VAL D 4 168 ? 362.251 357.323 482.556 1.00 55.52  ? 168 VAL B CG1 1 
ATOM 4601 C CG2 . VAL D 4 168 ? 361.157 355.507 483.842 1.00 55.52  ? 168 VAL B CG2 1 
ATOM 4602 N N   . GLN D 4 169 ? 364.330 358.862 484.763 1.00 55.15  ? 169 GLN B N   1 
ATOM 4603 C CA  . GLN D 4 169 ? 364.781 360.247 484.823 1.00 55.15  ? 169 GLN B CA  1 
ATOM 4604 C C   . GLN D 4 169 ? 363.980 361.059 483.825 1.00 55.15  ? 169 GLN B C   1 
ATOM 4605 O O   . GLN D 4 169 ? 364.120 360.874 482.614 1.00 55.15  ? 169 GLN B O   1 
ATOM 4606 C CB  . GLN D 4 169 ? 366.268 360.341 484.513 1.00 55.15  ? 169 GLN B CB  1 
ATOM 4607 C CG  . GLN D 4 169 ? 366.803 361.740 484.568 1.00 55.15  ? 169 GLN B CG  1 
ATOM 4608 C CD  . GLN D 4 169 ? 366.966 362.241 485.972 1.00 55.15  ? 169 GLN B CD  1 
ATOM 4609 O OE1 . GLN D 4 169 ? 366.103 362.930 486.505 1.00 55.15  ? 169 GLN B OE1 1 
ATOM 4610 N NE2 . GLN D 4 169 ? 368.090 361.914 486.580 1.00 55.15  ? 169 GLN B NE2 1 
ATOM 4611 N N   . THR D 4 170 ? 363.155 361.967 484.320 1.00 54.05  ? 170 THR B N   1 
ATOM 4612 C CA  . THR D 4 170 ? 362.177 362.655 483.495 1.00 54.05  ? 170 THR B CA  1 
ATOM 4613 C C   . THR D 4 170 ? 362.515 364.130 483.349 1.00 54.05  ? 170 THR B C   1 
ATOM 4614 O O   . THR D 4 170 ? 361.653 364.993 483.493 1.00 54.05  ? 170 THR B O   1 
ATOM 4615 C CB  . THR D 4 170 ? 360.773 362.488 484.063 1.00 54.05  ? 170 THR B CB  1 
ATOM 4616 O OG1 . THR D 4 170 ? 360.794 362.764 485.465 1.00 54.05  ? 170 THR B OG1 1 
ATOM 4617 C CG2 . THR D 4 170 ? 360.270 361.087 483.840 1.00 54.05  ? 170 THR B CG2 1 
ATOM 4618 N N   . ALA D 4 171 ? 363.781 364.439 483.083 1.00 52.82  ? 171 ALA B N   1 
ATOM 4619 C CA  . ALA D 4 171 ? 364.153 365.785 482.666 1.00 52.82  ? 171 ALA B CA  1 
ATOM 4620 C C   . ALA D 4 171 ? 363.664 366.012 481.244 1.00 52.82  ? 171 ALA B C   1 
ATOM 4621 O O   . ALA D 4 171 ? 364.094 365.316 480.321 1.00 52.82  ? 171 ALA B O   1 
ATOM 4622 C CB  . ALA D 4 171 ? 365.663 365.974 482.755 1.00 52.82  ? 171 ALA B CB  1 
ATOM 4623 N N   . VAL D 4 172 ? 362.764 366.979 481.064 1.00 48.73  ? 172 VAL B N   1 
ATOM 4624 C CA  . VAL D 4 172 ? 362.063 367.104 479.793 1.00 48.73  ? 172 VAL B CA  1 
ATOM 4625 C C   . VAL D 4 172 ? 362.958 367.643 478.685 1.00 48.73  ? 172 VAL B C   1 
ATOM 4626 O O   . VAL D 4 172 ? 362.739 367.321 477.514 1.00 48.73  ? 172 VAL B O   1 
ATOM 4627 C CB  . VAL D 4 172 ? 360.797 367.958 479.987 1.00 48.73  ? 172 VAL B CB  1 
ATOM 4628 C CG1 . VAL D 4 172 ? 361.132 369.409 480.283 1.00 48.73  ? 172 VAL B CG1 1 
ATOM 4629 C CG2 . VAL D 4 172 ? 359.845 367.833 478.809 1.00 48.73  ? 172 VAL B CG2 1 
ATOM 4630 N N   . TRP D 4 173 ? 364.009 368.394 479.012 1.00 49.74  ? 173 TRP B N   1 
ATOM 4631 C CA  . TRP D 4 173 ? 364.885 368.910 477.972 1.00 49.74  ? 173 TRP B CA  1 
ATOM 4632 C C   . TRP D 4 173 ? 365.846 367.862 477.442 1.00 49.74  ? 173 TRP B C   1 
ATOM 4633 O O   . TRP D 4 173 ? 366.580 368.146 476.494 1.00 49.74  ? 173 TRP B O   1 
ATOM 4634 C CB  . TRP D 4 173 ? 365.675 370.108 478.482 1.00 49.74  ? 173 TRP B CB  1 
ATOM 4635 C CG  . TRP D 4 173 ? 366.519 369.813 479.647 1.00 49.74  ? 173 TRP B CG  1 
ATOM 4636 C CD1 . TRP D 4 173 ? 367.815 369.419 479.638 1.00 49.74  ? 173 TRP B CD1 1 
ATOM 4637 C CD2 . TRP D 4 173 ? 366.134 369.901 481.015 1.00 49.74  ? 173 TRP B CD2 1 
ATOM 4638 N NE1 . TRP D 4 173 ? 368.267 369.249 480.916 1.00 49.74  ? 173 TRP B NE1 1 
ATOM 4639 C CE2 . TRP D 4 173 ? 367.249 369.539 481.783 1.00 49.74  ? 173 TRP B CE2 1 
ATOM 4640 C CE3 . TRP D 4 173 ? 364.951 370.249 481.666 1.00 49.74  ? 173 TRP B CE3 1 
ATOM 4641 C CZ2 . TRP D 4 173 ? 367.220 369.515 483.168 1.00 49.74  ? 173 TRP B CZ2 1 
ATOM 4642 C CZ3 . TRP D 4 173 ? 364.922 370.225 483.037 1.00 49.74  ? 173 TRP B CZ3 1 
ATOM 4643 C CH2 . TRP D 4 173 ? 366.047 369.861 483.775 1.00 49.74  ? 173 TRP B CH2 1 
ATOM 4644 N N   . ASN D 4 174 ? 365.879 366.679 478.045 1.00 50.85  ? 174 ASN B N   1 
ATOM 4645 C CA  . ASN D 4 174 ? 366.621 365.549 477.520 1.00 50.85  ? 174 ASN B CA  1 
ATOM 4646 C C   . ASN D 4 174 ? 365.713 364.452 477.005 1.00 50.85  ? 174 ASN B C   1 
ATOM 4647 O O   . ASN D 4 174 ? 366.212 363.468 476.454 1.00 50.85  ? 174 ASN B O   1 
ATOM 4648 C CB  . ASN D 4 174 ? 367.554 364.988 478.588 1.00 50.85  ? 174 ASN B CB  1 
ATOM 4649 C CG  . ASN D 4 174 ? 368.763 365.851 478.795 1.00 50.85  ? 174 ASN B CG  1 
ATOM 4650 O OD1 . ASN D 4 174 ? 369.452 365.743 479.801 1.00 50.85  ? 174 ASN B OD1 1 
ATOM 4651 N ND2 . ASN D 4 174 ? 369.029 366.724 477.840 1.00 50.85  ? 174 ASN B ND2 1 
ATOM 4652 N N   . ALA D 4 175 ? 364.399 364.594 477.198 1.00 51.62  ? 175 ALA B N   1 
ATOM 4653 C CA  . ALA D 4 175 ? 363.351 363.683 476.736 1.00 51.62  ? 175 ALA B CA  1 
ATOM 4654 C C   . ALA D 4 175 ? 363.517 362.267 477.264 1.00 51.62  ? 175 ALA B C   1 
ATOM 4655 O O   . ALA D 4 175 ? 363.035 361.319 476.643 1.00 51.62  ? 175 ALA B O   1 
ATOM 4656 C CB  . ALA D 4 175 ? 363.249 363.662 475.209 1.00 51.62  ? 175 ALA B CB  1 
ATOM 4657 N N   . GLY D 4 176 ? 364.196 362.095 478.398 1.00 51.23  ? 176 GLY B N   1 
ATOM 4658 C CA  . GLY D 4 176 ? 364.400 360.791 478.982 1.00 51.23  ? 176 GLY B CA  1 
ATOM 4659 C C   . GLY D 4 176 ? 365.317 359.870 478.215 1.00 51.23  ? 176 GLY B C   1 
ATOM 4660 O O   . GLY D 4 176 ? 365.337 358.671 478.502 1.00 51.23  ? 176 GLY B O   1 
ATOM 4661 N N   . MET D 4 177 ? 366.070 360.378 477.245 1.00 52.19  ? 177 MET B N   1 
ATOM 4662 C CA  . MET D 4 177 ? 366.954 359.551 476.439 1.00 52.19  ? 177 MET B CA  1 
ATOM 4663 C C   . MET D 4 177 ? 368.390 360.047 476.437 1.00 52.19  ? 177 MET B C   1 
ATOM 4664 O O   . MET D 4 177 ? 369.244 359.426 475.802 1.00 52.19  ? 177 MET B O   1 
ATOM 4665 C CB  . MET D 4 177 ? 366.436 359.466 475.006 1.00 52.19  ? 177 MET B CB  1 
ATOM 4666 C CG  . MET D 4 177 ? 365.122 358.742 474.869 1.00 52.19  ? 177 MET B CG  1 
ATOM 4667 S SD  . MET D 4 177 ? 364.594 358.641 473.161 1.00 52.19  ? 177 MET B SD  1 
ATOM 4668 C CE  . MET D 4 177 ? 364.113 360.329 472.894 1.00 52.19  ? 177 MET B CE  1 
ATOM 4669 N N   . GLY D 4 178 ? 368.681 361.146 477.123 1.00 50.64  ? 178 GLY B N   1 
ATOM 4670 C CA  . GLY D 4 178 ? 370.032 361.664 477.153 1.00 50.64  ? 178 GLY B CA  1 
ATOM 4671 C C   . GLY D 4 178 ? 370.442 362.426 475.919 1.00 50.64  ? 178 GLY B C   1 
ATOM 4672 O O   . GLY D 4 178 ? 371.615 362.401 475.549 1.00 50.64  ? 178 GLY B O   1 
ATOM 4673 N N   . VAL D 4 179 ? 369.512 363.122 475.282 1.00 49.59  ? 179 VAL B N   1 
ATOM 4674 C CA  . VAL D 4 179 ? 369.722 363.705 473.970 1.00 49.59  ? 179 VAL B CA  1 
ATOM 4675 C C   . VAL D 4 179 ? 369.235 365.151 474.032 1.00 49.59  ? 179 VAL B C   1 
ATOM 4676 O O   . VAL D 4 179 ? 368.752 365.611 475.064 1.00 49.59  ? 179 VAL B O   1 
ATOM 4677 C CB  . VAL D 4 179 ? 368.979 362.866 472.904 1.00 49.59  ? 179 VAL B CB  1 
ATOM 4678 C CG1 . VAL D 4 179 ? 367.474 363.155 472.890 1.00 49.59  ? 179 VAL B CG1 1 
ATOM 4679 C CG2 . VAL D 4 179 ? 369.629 362.936 471.550 1.00 49.59  ? 179 VAL B CG2 1 
ATOM 4680 N N   . GLY D 4 180 ? 369.403 365.888 472.939 1.00 48.56  ? 180 GLY B N   1 
ATOM 4681 C CA  . GLY D 4 180 ? 368.817 367.215 472.863 1.00 48.56  ? 180 GLY B CA  1 
ATOM 4682 C C   . GLY D 4 180 ? 367.362 367.143 472.436 1.00 48.56  ? 180 GLY B C   1 
ATOM 4683 O O   . GLY D 4 180 ? 367.014 366.485 471.457 1.00 48.56  ? 180 GLY B O   1 
ATOM 4684 N N   . VAL D 4 181 ? 366.497 367.833 473.183 1.00 46.12  ? 181 VAL B N   1 
ATOM 4685 C CA  . VAL D 4 181 ? 365.065 367.718 472.925 1.00 46.12  ? 181 VAL B CA  1 
ATOM 4686 C C   . VAL D 4 181 ? 364.651 368.502 471.689 1.00 46.12  ? 181 VAL B C   1 
ATOM 4687 O O   . VAL D 4 181 ? 363.599 368.220 471.108 1.00 46.12  ? 181 VAL B O   1 
ATOM 4688 C CB  . VAL D 4 181 ? 364.246 368.145 474.159 1.00 46.12  ? 181 VAL B CB  1 
ATOM 4689 C CG1 . VAL D 4 181 ? 364.139 369.647 474.278 1.00 46.12  ? 181 VAL B CG1 1 
ATOM 4690 C CG2 . VAL D 4 181 ? 362.871 367.502 474.163 1.00 46.12  ? 181 VAL B CG2 1 
ATOM 4691 N N   . GLY D 4 182 ? 365.460 369.458 471.239 1.00 44.47  ? 182 GLY B N   1 
ATOM 4692 C CA  . GLY D 4 182 ? 365.147 370.125 469.996 1.00 44.47  ? 182 GLY B CA  1 
ATOM 4693 C C   . GLY D 4 182 ? 365.392 369.280 468.771 1.00 44.47  ? 182 GLY B C   1 
ATOM 4694 O O   . GLY D 4 182 ? 364.760 369.510 467.739 1.00 44.47  ? 182 GLY B O   1 
ATOM 4695 N N   . ASN D 4 183 ? 366.278 368.296 468.864 1.00 44.62  ? 183 ASN B N   1 
ATOM 4696 C CA  . ASN D 4 183 ? 366.621 367.450 467.734 1.00 44.62  ? 183 ASN B CA  1 
ATOM 4697 C C   . ASN D 4 183 ? 365.701 366.250 467.589 1.00 44.62  ? 183 ASN B C   1 
ATOM 4698 O O   . ASN D 4 183 ? 365.995 365.353 466.799 1.00 44.62  ? 183 ASN B O   1 
ATOM 4699 C CB  . ASN D 4 183 ? 368.062 366.974 467.855 1.00 44.62  ? 183 ASN B CB  1 
ATOM 4700 C CG  . ASN D 4 183 ? 369.008 368.095 468.125 1.00 44.62  ? 183 ASN B CG  1 
ATOM 4701 O OD1 . ASN D 4 183 ? 368.725 369.242 467.800 1.00 44.62  ? 183 ASN B OD1 1 
ATOM 4702 N ND2 . ASN D 4 183 ? 370.147 367.778 468.720 1.00 44.62  ? 183 ASN B ND2 1 
ATOM 4703 N N   . LEU D 4 184 ? 364.586 366.222 468.307 1.00 44.04  ? 184 LEU B N   1 
ATOM 4704 C CA  . LEU D 4 184 ? 363.623 365.140 468.186 1.00 44.04  ? 184 LEU B CA  1 
ATOM 4705 C C   . LEU D 4 184 ? 362.815 365.197 466.901 1.00 44.04  ? 184 LEU B C   1 
ATOM 4706 O O   . LEU D 4 184 ? 362.003 364.301 466.665 1.00 44.04  ? 184 LEU B O   1 
ATOM 4707 C CB  . LEU D 4 184 ? 362.674 365.157 469.376 1.00 44.04  ? 184 LEU B CB  1 
ATOM 4708 C CG  . LEU D 4 184 ? 363.126 364.372 470.595 1.00 44.04  ? 184 LEU B CG  1 
ATOM 4709 C CD1 . LEU D 4 184 ? 362.235 364.696 471.748 1.00 44.04  ? 184 LEU B CD1 1 
ATOM 4710 C CD2 . LEU D 4 184 ? 363.086 362.899 470.310 1.00 44.04  ? 184 LEU B CD2 1 
ATOM 4711 N N   . THR D 4 185 ? 363.008 366.214 466.070 1.00 45.29  ? 185 THR B N   1 
ATOM 4712 C CA  . THR D 4 185 ? 362.281 366.375 464.823 1.00 45.29  ? 185 THR B CA  1 
ATOM 4713 C C   . THR D 4 185 ? 362.818 365.500 463.704 1.00 45.29  ? 185 THR B C   1 
ATOM 4714 O O   . THR D 4 185 ? 362.293 365.565 462.592 1.00 45.29  ? 185 THR B O   1 
ATOM 4715 C CB  . THR D 4 185 ? 362.322 367.833 464.378 1.00 45.29  ? 185 THR B CB  1 
ATOM 4716 O OG1 . THR D 4 185 ? 363.552 368.071 463.697 1.00 45.29  ? 185 THR B OG1 1 
ATOM 4717 C CG2 . THR D 4 185 ? 362.250 368.752 465.573 1.00 45.29  ? 185 THR B CG2 1 
ATOM 4718 N N   . ILE D 4 186 ? 363.849 364.694 463.954 1.00 44.67  ? 186 ILE B N   1 
ATOM 4719 C CA  . ILE D 4 186 ? 364.320 363.776 462.927 1.00 44.67  ? 186 ILE B CA  1 
ATOM 4720 C C   . ILE D 4 186 ? 363.388 362.579 462.793 1.00 44.67  ? 186 ILE B C   1 
ATOM 4721 O O   . ILE D 4 186 ? 363.308 361.974 461.717 1.00 44.67  ? 186 ILE B O   1 
ATOM 4722 C CB  . ILE D 4 186 ? 365.774 363.377 463.233 1.00 44.67  ? 186 ILE B CB  1 
ATOM 4723 C CG1 . ILE D 4 186 ? 366.423 362.674 462.045 1.00 44.67  ? 186 ILE B CG1 1 
ATOM 4724 C CG2 . ILE D 4 186 ? 365.855 362.545 464.468 1.00 44.67  ? 186 ILE B CG2 1 
ATOM 4725 C CD1 . ILE D 4 186 ? 367.807 362.193 462.321 1.00 44.67  ? 186 ILE B CD1 1 
ATOM 4726 N N   . PHE D 4 187 ? 362.631 362.262 463.831 1.00 45.45  ? 187 PHE B N   1 
ATOM 4727 C CA  . PHE D 4 187 ? 361.594 361.252 463.765 1.00 45.45  ? 187 PHE B CA  1 
ATOM 4728 C C   . PHE D 4 187 ? 360.394 361.831 463.029 1.00 45.45  ? 187 PHE B C   1 
ATOM 4729 O O   . PHE D 4 187 ? 360.336 363.035 462.784 1.00 45.45  ? 187 PHE B O   1 
ATOM 4730 C CB  . PHE D 4 187 ? 361.252 360.809 465.183 1.00 45.45  ? 187 PHE B CB  1 
ATOM 4731 C CG  . PHE D 4 187 ? 362.419 360.256 465.932 1.00 45.45  ? 187 PHE B CG  1 
ATOM 4732 C CD1 . PHE D 4 187 ? 363.011 359.077 465.532 1.00 45.45  ? 187 PHE B CD1 1 
ATOM 4733 C CD2 . PHE D 4 187 ? 362.927 360.912 467.034 1.00 45.45  ? 187 PHE B CD2 1 
ATOM 4734 C CE1 . PHE D 4 187 ? 364.076 358.566 466.218 1.00 45.45  ? 187 PHE B CE1 1 
ATOM 4735 C CE2 . PHE D 4 187 ? 364.001 360.400 467.721 1.00 45.45  ? 187 PHE B CE2 1 
ATOM 4736 C CZ  . PHE D 4 187 ? 364.568 359.229 467.311 1.00 45.45  ? 187 PHE B CZ  1 
ATOM 4737 N N   . PRO D 4 188 ? 359.439 361.002 462.605 1.00 46.88  ? 188 PRO B N   1 
ATOM 4738 C CA  . PRO D 4 188 ? 358.194 361.558 462.058 1.00 46.88  ? 188 PRO B CA  1 
ATOM 4739 C C   . PRO D 4 188 ? 357.419 362.320 463.119 1.00 46.88  ? 188 PRO B C   1 
ATOM 4740 O O   . PRO D 4 188 ? 357.251 361.856 464.245 1.00 46.88  ? 188 PRO B O   1 
ATOM 4741 C CB  . PRO D 4 188 ? 357.440 360.317 461.569 1.00 46.88  ? 188 PRO B CB  1 
ATOM 4742 C CG  . PRO D 4 188 ? 358.132 359.171 462.179 1.00 46.88  ? 188 PRO B CG  1 
ATOM 4743 C CD  . PRO D 4 188 ? 359.546 359.570 462.296 1.00 46.88  ? 188 PRO B CD  1 
ATOM 4744 N N   . HIS D 4 189 ? 356.966 363.517 462.755 1.00 45.28  ? 189 HIS B N   1 
ATOM 4745 C CA  . HIS D 4 189 ? 356.406 364.447 463.716 1.00 45.28  ? 189 HIS B CA  1 
ATOM 4746 C C   . HIS D 4 189 ? 355.402 365.361 463.030 1.00 45.28  ? 189 HIS B C   1 
ATOM 4747 O O   . HIS D 4 189 ? 355.188 365.289 461.817 1.00 45.28  ? 189 HIS B O   1 
ATOM 4748 C CB  . HIS D 4 189 ? 357.508 365.273 464.376 1.00 45.28  ? 189 HIS B CB  1 
ATOM 4749 C CG  . HIS D 4 189 ? 358.165 366.241 463.450 1.00 45.28  ? 189 HIS B CG  1 
ATOM 4750 N ND1 . HIS D 4 189 ? 358.909 365.840 462.363 1.00 45.28  ? 189 HIS B ND1 1 
ATOM 4751 C CD2 . HIS D 4 189 ? 358.185 367.592 463.441 1.00 45.28  ? 189 HIS B CD2 1 
ATOM 4752 C CE1 . HIS D 4 189 ? 359.362 366.903 461.727 1.00 45.28  ? 189 HIS B CE1 1 
ATOM 4753 N NE2 . HIS D 4 189 ? 358.936 367.980 462.361 1.00 45.28  ? 189 HIS B NE2 1 
ATOM 4754 N N   . GLN D 4 190 ? 354.801 366.240 463.828 1.00 47.08  ? 190 GLN B N   1 
ATOM 4755 C CA  . GLN D 4 190 ? 353.829 367.221 463.373 1.00 47.08  ? 190 GLN B CA  1 
ATOM 4756 C C   . GLN D 4 190 ? 353.697 368.276 464.456 1.00 47.08  ? 190 GLN B C   1 
ATOM 4757 O O   . GLN D 4 190 ? 353.498 367.939 465.621 1.00 47.08  ? 190 GLN B O   1 
ATOM 4758 C CB  . GLN D 4 190 ? 352.469 366.574 463.100 1.00 47.08  ? 190 GLN B CB  1 
ATOM 4759 C CG  . GLN D 4 190 ? 351.382 367.533 462.679 1.00 47.08  ? 190 GLN B CG  1 
ATOM 4760 C CD  . GLN D 4 190 ? 351.344 367.761 461.191 1.00 47.08  ? 190 GLN B CD  1 
ATOM 4761 O OE1 . GLN D 4 190 ? 351.650 368.849 460.708 1.00 47.08  ? 190 GLN B OE1 1 
ATOM 4762 N NE2 . GLN D 4 190 ? 350.965 366.732 460.449 1.00 47.08  ? 190 GLN B NE2 1 
ATOM 4763 N N   . TRP D 4 191 ? 353.823 369.540 464.077 1.00 43.34  ? 191 TRP B N   1 
ATOM 4764 C CA  . TRP D 4 191 ? 353.691 370.634 465.028 1.00 43.34  ? 191 TRP B CA  1 
ATOM 4765 C C   . TRP D 4 191 ? 352.239 371.079 465.117 1.00 43.34  ? 191 TRP B C   1 
ATOM 4766 O O   . TRP D 4 191 ? 351.631 371.451 464.111 1.00 43.34  ? 191 TRP B O   1 
ATOM 4767 C CB  . TRP D 4 191 ? 354.560 371.822 464.619 1.00 43.34  ? 191 TRP B CB  1 
ATOM 4768 C CG  . TRP D 4 191 ? 356.016 371.623 464.817 1.00 43.34  ? 191 TRP B CG  1 
ATOM 4769 C CD1 . TRP D 4 191 ? 356.893 371.103 463.926 1.00 43.34  ? 191 TRP B CD1 1 
ATOM 4770 C CD2 . TRP D 4 191 ? 356.774 371.953 465.980 1.00 43.34  ? 191 TRP B CD2 1 
ATOM 4771 N NE1 . TRP D 4 191 ? 358.152 371.081 464.459 1.00 43.34  ? 191 TRP B NE1 1 
ATOM 4772 C CE2 . TRP D 4 191 ? 358.103 371.600 465.723 1.00 43.34  ? 191 TRP B CE2 1 
ATOM 4773 C CE3 . TRP D 4 191 ? 356.455 372.513 467.215 1.00 43.34  ? 191 TRP B CE3 1 
ATOM 4774 C CZ2 . TRP D 4 191 ? 359.112 371.785 466.652 1.00 43.34  ? 191 TRP B CZ2 1 
ATOM 4775 C CZ3 . TRP D 4 191 ? 357.457 372.699 468.134 1.00 43.34  ? 191 TRP B CZ3 1 
ATOM 4776 C CH2 . TRP D 4 191 ? 358.767 372.336 467.851 1.00 43.34  ? 191 TRP B CH2 1 
ATOM 4777 N N   . ILE D 4 192 ? 351.690 371.056 466.323 1.00 42.99  ? 192 ILE B N   1 
ATOM 4778 C CA  . ILE D 4 192 ? 350.339 371.539 466.570 1.00 42.99  ? 192 ILE B CA  1 
ATOM 4779 C C   . ILE D 4 192 ? 350.471 372.943 467.141 1.00 42.99  ? 192 ILE B C   1 
ATOM 4780 O O   . ILE D 4 192 ? 350.806 373.123 468.315 1.00 42.99  ? 192 ILE B O   1 
ATOM 4781 C CB  . ILE D 4 192 ? 349.557 370.622 467.511 1.00 42.99  ? 192 ILE B CB  1 
ATOM 4782 C CG1 . ILE D 4 192 ? 349.372 369.252 466.879 1.00 42.99  ? 192 ILE B CG1 1 
ATOM 4783 C CG2 . ILE D 4 192 ? 348.201 371.211 467.812 1.00 42.99  ? 192 ILE B CG2 1 
ATOM 4784 C CD1 . ILE D 4 192 ? 348.601 368.296 467.750 1.00 42.99  ? 192 ILE B CD1 1 
ATOM 4785 N N   . ASN D 4 193 ? 350.225 373.942 466.306 1.00 43.99  ? 193 ASN B N   1 
ATOM 4786 C CA  . ASN D 4 193 ? 350.271 375.343 466.694 1.00 43.99  ? 193 ASN B CA  1 
ATOM 4787 C C   . ASN D 4 193 ? 348.839 375.830 466.814 1.00 43.99  ? 193 ASN B C   1 
ATOM 4788 O O   . ASN D 4 193 ? 348.088 375.776 465.839 1.00 43.99  ? 193 ASN B O   1 
ATOM 4789 C CB  . ASN D 4 193 ? 351.039 376.164 465.662 1.00 43.99  ? 193 ASN B CB  1 
ATOM 4790 C CG  . ASN D 4 193 ? 351.362 377.553 466.142 1.00 43.99  ? 193 ASN B CG  1 
ATOM 4791 O OD1 . ASN D 4 193 ? 351.107 377.899 467.287 1.00 43.99  ? 193 ASN B OD1 1 
ATOM 4792 N ND2 . ASN D 4 193 ? 351.933 378.361 465.265 1.00 43.99  ? 193 ASN B ND2 1 
ATOM 4793 N N   . LEU D 4 194 ? 348.465 376.315 467.999 1.00 43.42  ? 194 LEU B N   1 
ATOM 4794 C CA  . LEU D 4 194 ? 347.073 376.673 468.248 1.00 43.42  ? 194 LEU B CA  1 
ATOM 4795 C C   . LEU D 4 194 ? 346.633 377.899 467.468 1.00 43.42  ? 194 LEU B C   1 
ATOM 4796 O O   . LEU D 4 194 ? 345.431 378.114 467.300 1.00 43.42  ? 194 LEU B O   1 
ATOM 4797 C CB  . LEU D 4 194 ? 346.849 376.910 469.735 1.00 43.42  ? 194 LEU B CB  1 
ATOM 4798 C CG  . LEU D 4 194 ? 346.657 375.659 470.579 1.00 43.42  ? 194 LEU B CG  1 
ATOM 4799 C CD1 . LEU D 4 194 ? 346.418 376.053 472.006 1.00 43.42  ? 194 LEU B CD1 1 
ATOM 4800 C CD2 . LEU D 4 194 ? 345.502 374.856 470.053 1.00 43.42  ? 194 LEU B CD2 1 
ATOM 4801 N N   . ARG D 4 195 ? 347.579 378.700 466.990 1.00 47.58  ? 195 ARG B N   1 
ATOM 4802 C CA  . ARG D 4 195 ? 347.240 379.862 466.182 1.00 47.58  ? 195 ARG B CA  1 
ATOM 4803 C C   . ARG D 4 195 ? 346.747 379.449 464.801 1.00 47.58  ? 195 ARG B C   1 
ATOM 4804 O O   . ARG D 4 195 ? 345.827 380.066 464.255 1.00 47.58  ? 195 ARG B O   1 
ATOM 4805 C CB  . ARG D 4 195 ? 348.464 380.770 466.092 1.00 47.58  ? 195 ARG B CB  1 
ATOM 4806 C CG  . ARG D 4 195 ? 348.377 381.864 465.090 1.00 47.58  ? 195 ARG B CG  1 
ATOM 4807 C CD  . ARG D 4 195 ? 349.730 382.471 464.840 1.00 47.58  ? 195 ARG B CD  1 
ATOM 4808 N NE  . ARG D 4 195 ? 349.634 383.522 463.844 1.00 47.58  ? 195 ARG B NE  1 
ATOM 4809 C CZ  . ARG D 4 195 ? 349.337 384.780 464.130 1.00 47.58  ? 195 ARG B CZ  1 
ATOM 4810 N NH1 . ARG D 4 195 ? 349.125 385.143 465.383 1.00 47.58  ? 195 ARG B NH1 1 
ATOM 4811 N NH2 . ARG D 4 195 ? 349.255 385.671 463.162 1.00 47.58  ? 195 ARG B NH2 1 
ATOM 4812 N N   . THR D 4 196 ? 347.321 378.389 464.232 1.00 47.88  ? 196 THR B N   1 
ATOM 4813 C CA  . THR D 4 196 ? 347.005 377.979 462.870 1.00 47.88  ? 196 THR B CA  1 
ATOM 4814 C C   . THR D 4 196 ? 346.423 376.580 462.740 1.00 47.88  ? 196 THR B C   1 
ATOM 4815 O O   . THR D 4 196 ? 345.600 376.364 461.845 1.00 47.88  ? 196 THR B O   1 
ATOM 4816 C CB  . THR D 4 196 ? 348.257 378.039 461.985 1.00 47.88  ? 196 THR B CB  1 
ATOM 4817 O OG1 . THR D 4 196 ? 349.222 377.100 462.466 1.00 47.88  ? 196 THR B OG1 1 
ATOM 4818 C CG2 . THR D 4 196 ? 348.867 379.424 462.002 1.00 47.88  ? 196 THR B CG2 1 
ATOM 4819 N N   . ASN D 4 197 ? 346.815 375.631 463.581 1.00 49.12  ? 197 ASN B N   1 
ATOM 4820 C CA  . ASN D 4 197 ? 346.517 374.224 463.372 1.00 49.12  ? 197 ASN B CA  1 
ATOM 4821 C C   . ASN D 4 197 ? 345.662 373.706 464.517 1.00 49.12  ? 197 ASN B C   1 
ATOM 4822 O O   . ASN D 4 197 ? 345.611 374.293 465.597 1.00 49.12  ? 197 ASN B O   1 
ATOM 4823 C CB  . ASN D 4 197 ? 347.810 373.413 463.263 1.00 49.12  ? 197 ASN B CB  1 
ATOM 4824 C CG  . ASN D 4 197 ? 347.602 372.071 462.622 1.00 49.12  ? 197 ASN B CG  1 
ATOM 4825 O OD1 . ASN D 4 197 ? 346.507 371.758 462.161 1.00 49.12  ? 197 ASN B OD1 1 
ATOM 4826 N ND2 . ASN D 4 197 ? 348.651 371.260 462.590 1.00 49.12  ? 197 ASN B ND2 1 
ATOM 4827 N N   . ASN D 4 198 ? 344.986 372.590 464.273 1.00 50.65  ? 198 ASN B N   1 
ATOM 4828 C CA  . ASN D 4 198 ? 344.101 372.025 465.282 1.00 50.65  ? 198 ASN B CA  1 
ATOM 4829 C C   . ASN D 4 198 ? 344.411 370.587 465.653 1.00 50.65  ? 198 ASN B C   1 
ATOM 4830 O O   . ASN D 4 198 ? 344.161 370.208 466.801 1.00 50.65  ? 198 ASN B O   1 
ATOM 4831 C CB  . ASN D 4 198 ? 342.649 372.103 464.807 1.00 50.65  ? 198 ASN B CB  1 
ATOM 4832 C CG  . ASN D 4 198 ? 341.725 372.643 465.863 1.00 50.65  ? 198 ASN B CG  1 
ATOM 4833 O OD1 . ASN D 4 198 ? 342.020 372.577 467.052 1.00 50.65  ? 198 ASN B OD1 1 
ATOM 4834 N ND2 . ASN D 4 198 ? 340.597 373.190 465.435 1.00 50.65  ? 198 ASN B ND2 1 
ATOM 4835 N N   . SER D 4 199 ? 344.951 369.773 464.752 1.00 50.87  ? 199 SER B N   1 
ATOM 4836 C CA  . SER D 4 199 ? 345.106 368.352 465.000 1.00 50.87  ? 199 SER B CA  1 
ATOM 4837 C C   . SER D 4 199 ? 346.353 367.828 464.309 1.00 50.87  ? 199 SER B C   1 
ATOM 4838 O O   . SER D 4 199 ? 347.065 368.562 463.624 1.00 50.87  ? 199 SER B O   1 
ATOM 4839 C CB  . SER D 4 199 ? 343.884 367.575 464.514 1.00 50.87  ? 199 SER B CB  1 
ATOM 4840 O OG  . SER D 4 199 ? 343.746 367.681 463.110 1.00 50.87  ? 199 SER B OG  1 
ATOM 4841 N N   . ALA D 4 200 ? 346.602 366.534 464.491 1.00 49.76  ? 200 ALA B N   1 
ATOM 4842 C CA  . ALA D 4 200 ? 347.746 365.867 463.892 1.00 49.76  ? 200 ALA B CA  1 
ATOM 4843 C C   . ALA D 4 200 ? 347.344 364.466 463.465 1.00 49.76  ? 200 ALA B C   1 
ATOM 4844 O O   . ALA D 4 200 ? 346.399 363.883 463.995 1.00 49.76  ? 200 ALA B O   1 
ATOM 4845 C CB  . ALA D 4 200 ? 348.928 365.794 464.860 1.00 49.76  ? 200 ALA B CB  1 
ATOM 4846 N N   . THR D 4 201 ? 348.074 363.931 462.490 1.00 54.00  ? 201 THR B N   1 
ATOM 4847 C CA  . THR D 4 201 ? 347.857 362.566 462.021 1.00 54.00  ? 201 THR B CA  1 
ATOM 4848 C C   . THR D 4 201 ? 349.208 361.959 461.692 1.00 54.00  ? 201 THR B C   1 
ATOM 4849 O O   . THR D 4 201 ? 350.047 362.624 461.086 1.00 54.00  ? 201 THR B O   1 
ATOM 4850 C CB  . THR D 4 201 ? 346.952 362.532 460.794 1.00 54.00  ? 201 THR B CB  1 
ATOM 4851 O OG1 . THR D 4 201 ? 345.845 363.420 460.984 1.00 54.00  ? 201 THR B OG1 1 
ATOM 4852 C CG2 . THR D 4 201 ? 346.424 361.129 460.564 1.00 54.00  ? 201 THR B CG2 1 
ATOM 4853 N N   . LEU D 4 202 ? 349.424 360.712 462.096 1.00 52.95  ? 202 LEU B N   1 
ATOM 4854 C CA  . LEU D 4 202 ? 350.684 360.017 461.877 1.00 52.95  ? 202 LEU B CA  1 
ATOM 4855 C C   . LEU D 4 202 ? 350.402 358.583 461.473 1.00 52.95  ? 202 LEU B C   1 
ATOM 4856 O O   . LEU D 4 202 ? 349.709 357.865 462.193 1.00 52.95  ? 202 LEU B O   1 
ATOM 4857 C CB  . LEU D 4 202 ? 351.550 360.033 463.134 1.00 52.95  ? 202 LEU B CB  1 
ATOM 4858 C CG  . LEU D 4 202 ? 352.113 361.360 463.619 1.00 52.95  ? 202 LEU B CG  1 
ATOM 4859 C CD1 . LEU D 4 202 ? 352.305 361.312 465.105 1.00 52.95  ? 202 LEU B CD1 1 
ATOM 4860 C CD2 . LEU D 4 202 ? 353.429 361.570 462.946 1.00 52.95  ? 202 LEU B CD2 1 
ATOM 4861 N N   . VAL D 4 203 ? 350.951 358.163 460.343 1.00 57.10  ? 203 VAL B N   1 
ATOM 4862 C CA  . VAL D 4 203 ? 350.820 356.794 459.864 1.00 57.10  ? 203 VAL B CA  1 
ATOM 4863 C C   . VAL D 4 203 ? 352.181 356.137 460.013 1.00 57.10  ? 203 VAL B C   1 
ATOM 4864 O O   . VAL D 4 203 ? 353.138 356.527 459.338 1.00 57.10  ? 203 VAL B O   1 
ATOM 4865 C CB  . VAL D 4 203 ? 350.341 356.735 458.411 1.00 57.10  ? 203 VAL B CB  1 
ATOM 4866 C CG1 . VAL D 4 203 ? 350.283 355.303 457.945 1.00 57.10  ? 203 VAL B CG1 1 
ATOM 4867 C CG2 . VAL D 4 203 ? 348.991 357.385 458.280 1.00 57.10  ? 203 VAL B CG2 1 
ATOM 4868 N N   . MET D 4 204 ? 352.274 355.142 460.885 1.00 60.99  ? 204 MET B N   1 
ATOM 4869 C CA  . MET D 4 204 ? 353.561 354.560 461.215 1.00 60.99  ? 204 MET B CA  1 
ATOM 4870 C C   . MET D 4 204 ? 353.631 353.111 460.777 1.00 60.99  ? 204 MET B C   1 
ATOM 4871 O O   . MET D 4 204 ? 352.763 352.316 461.153 1.00 60.99  ? 204 MET B O   1 
ATOM 4872 C CB  . MET D 4 204 ? 353.811 354.652 462.713 1.00 60.99  ? 204 MET B CB  1 
ATOM 4873 C CG  . MET D 4 204 ? 354.149 356.031 463.157 1.00 60.99  ? 204 MET B CG  1 
ATOM 4874 S SD  . MET D 4 204 ? 355.552 356.634 462.227 1.00 60.99  ? 204 MET B SD  1 
ATOM 4875 C CE  . MET D 4 204 ? 356.846 355.592 462.875 1.00 60.99  ? 204 MET B CE  1 
ATOM 4876 N N   . PRO D 4 205 ? 354.645 352.724 460.017 1.00 59.85  ? 205 PRO B N   1 
ATOM 4877 C CA  . PRO D 4 205 ? 354.767 351.324 459.610 1.00 59.85  ? 205 PRO B CA  1 
ATOM 4878 C C   . PRO D 4 205 ? 355.284 350.431 460.723 1.00 59.85  ? 205 PRO B C   1 
ATOM 4879 O O   . PRO D 4 205 ? 355.430 350.864 461.868 1.00 59.85  ? 205 PRO B O   1 
ATOM 4880 C CB  . PRO D 4 205 ? 355.756 351.396 458.446 1.00 59.85  ? 205 PRO B CB  1 
ATOM 4881 C CG  . PRO D 4 205 ? 356.567 352.575 458.734 1.00 59.85  ? 205 PRO B CG  1 
ATOM 4882 C CD  . PRO D 4 205 ? 355.662 353.566 459.374 1.00 59.85  ? 205 PRO B CD  1 
ATOM 4883 N N   . TYR D 4 206 ? 355.550 349.171 460.402 1.00 63.41  ? 206 TYR B N   1 
ATOM 4884 C CA  . TYR D 4 206 ? 356.151 348.247 461.350 1.00 63.41  ? 206 TYR B CA  1 
ATOM 4885 C C   . TYR D 4 206 ? 357.659 348.294 461.176 1.00 63.41  ? 206 TYR B C   1 
ATOM 4886 O O   . TYR D 4 206 ? 358.182 347.840 460.156 1.00 63.41  ? 206 TYR B O   1 
ATOM 4887 C CB  . TYR D 4 206 ? 355.636 346.828 461.140 1.00 63.41  ? 206 TYR B CB  1 
ATOM 4888 C CG  . TYR D 4 206 ? 356.278 345.832 462.067 1.00 63.41  ? 206 TYR B CG  1 
ATOM 4889 C CD1 . TYR D 4 206 ? 356.106 345.929 463.436 1.00 63.41  ? 206 TYR B CD1 1 
ATOM 4890 C CD2 . TYR D 4 206 ? 357.068 344.805 461.577 1.00 63.41  ? 206 TYR B CD2 1 
ATOM 4891 C CE1 . TYR D 4 206 ? 356.694 345.032 464.290 1.00 63.41  ? 206 TYR B CE1 1 
ATOM 4892 C CE2 . TYR D 4 206 ? 357.664 343.903 462.427 1.00 63.41  ? 206 TYR B CE2 1 
ATOM 4893 C CZ  . TYR D 4 206 ? 357.469 344.025 463.782 1.00 63.41  ? 206 TYR B CZ  1 
ATOM 4894 O OH  . TYR D 4 206 ? 358.053 343.136 464.645 1.00 63.41  ? 206 TYR B OH  1 
ATOM 4895 N N   . ILE D 4 207 ? 358.353 348.844 462.165 1.00 55.43  ? 207 ILE B N   1 
ATOM 4896 C CA  . ILE D 4 207 ? 359.793 349.046 462.105 1.00 55.43  ? 207 ILE B CA  1 
ATOM 4897 C C   . ILE D 4 207 ? 360.424 348.164 463.168 1.00 55.43  ? 207 ILE B C   1 
ATOM 4898 O O   . ILE D 4 207 ? 360.275 348.429 464.367 1.00 55.43  ? 207 ILE B O   1 
ATOM 4899 C CB  . ILE D 4 207 ? 360.174 350.514 462.315 1.00 55.43  ? 207 ILE B CB  1 
ATOM 4900 C CG1 . ILE D 4 207 ? 359.406 351.407 461.354 1.00 55.43  ? 207 ILE B CG1 1 
ATOM 4901 C CG2 . ILE D 4 207 ? 361.639 350.713 462.087 1.00 55.43  ? 207 ILE B CG2 1 
ATOM 4902 C CD1 . ILE D 4 207 ? 359.241 352.815 461.855 1.00 55.43  ? 207 ILE B CD1 1 
ATOM 4903 N N   . ASN D 4 208 ? 361.135 347.127 462.733 1.00 55.42  ? 208 ASN B N   1 
ATOM 4904 C CA  . ASN D 4 208 ? 361.814 346.198 463.627 1.00 55.42  ? 208 ASN B CA  1 
ATOM 4905 C C   . ASN D 4 208 ? 362.843 345.432 462.811 1.00 55.42  ? 208 ASN B C   1 
ATOM 4906 O O   . ASN D 4 208 ? 362.778 345.392 461.582 1.00 55.42  ? 208 ASN B O   1 
ATOM 4907 C CB  . ASN D 4 208 ? 360.829 345.240 464.298 1.00 55.42  ? 208 ASN B CB  1 
ATOM 4908 C CG  . ASN D 4 208 ? 361.404 344.580 465.519 1.00 55.42  ? 208 ASN B CG  1 
ATOM 4909 O OD1 . ASN D 4 208 ? 362.499 344.918 465.958 1.00 55.42  ? 208 ASN B OD1 1 
ATOM 4910 N ND2 . ASN D 4 208 ? 360.678 343.625 466.071 1.00 55.42  ? 208 ASN B ND2 1 
ATOM 4911 N N   . SER D 4 209 ? 363.794 344.815 463.511 1.00 54.65  ? 209 SER B N   1 
ATOM 4912 C CA  . SER D 4 209 ? 364.858 344.059 462.865 1.00 54.65  ? 209 SER B CA  1 
ATOM 4913 C C   . SER D 4 209 ? 364.462 342.631 462.537 1.00 54.65  ? 209 SER B C   1 
ATOM 4914 O O   . SER D 4 209 ? 365.017 342.048 461.604 1.00 54.65  ? 209 SER B O   1 
ATOM 4915 C CB  . SER D 4 209 ? 366.099 344.038 463.751 1.00 54.65  ? 209 SER B CB  1 
ATOM 4916 O OG  . SER D 4 209 ? 366.017 343.000 464.703 1.00 54.65  ? 209 SER B OG  1 
ATOM 4917 N N   . VAL D 4 210 ? 363.532 342.046 463.285 1.00 59.45  ? 210 VAL B N   1 
ATOM 4918 C CA  . VAL D 4 210 ? 363.024 340.705 463.005 1.00 59.45  ? 210 VAL B CA  1 
ATOM 4919 C C   . VAL D 4 210 ? 361.595 340.837 462.489 1.00 59.45  ? 210 VAL B C   1 
ATOM 4920 O O   . VAL D 4 210 ? 360.905 341.801 462.845 1.00 59.45  ? 210 VAL B O   1 
ATOM 4921 C CB  . VAL D 4 210 ? 363.099 339.817 464.253 1.00 59.45  ? 210 VAL B CB  1 
ATOM 4922 C CG1 . VAL D 4 210 ? 364.522 339.453 464.531 1.00 59.45  ? 210 VAL B CG1 1 
ATOM 4923 C CG2 . VAL D 4 210 ? 362.520 340.537 465.435 1.00 59.45  ? 210 VAL B CG2 1 
ATOM 4924 N N   . PRO D 4 211 ? 361.111 339.924 461.642 1.00 65.97  ? 211 PRO B N   1 
ATOM 4925 C CA  . PRO D 4 211 ? 359.756 340.096 461.100 1.00 65.97  ? 211 PRO B CA  1 
ATOM 4926 C C   . PRO D 4 211 ? 358.646 339.791 462.092 1.00 65.97  ? 211 PRO B C   1 
ATOM 4927 O O   . PRO D 4 211 ? 357.527 340.282 461.912 1.00 65.97  ? 211 PRO B O   1 
ATOM 4928 C CB  . PRO D 4 211 ? 359.734 339.127 459.914 1.00 65.97  ? 211 PRO B CB  1 
ATOM 4929 C CG  . PRO D 4 211 ? 360.741 338.117 460.249 1.00 65.97  ? 211 PRO B CG  1 
ATOM 4930 C CD  . PRO D 4 211 ? 361.829 338.839 460.958 1.00 65.97  ? 211 PRO B CD  1 
ATOM 4931 N N   . MET D 4 212 ? 358.911 338.999 463.127 1.00 78.22  ? 212 MET B N   1 
ATOM 4932 C CA  . MET D 4 212 ? 357.943 338.732 464.181 1.00 78.22  ? 212 MET B CA  1 
ATOM 4933 C C   . MET D 4 212 ? 358.677 338.676 465.508 1.00 78.22  ? 212 MET B C   1 
ATOM 4934 O O   . MET D 4 212 ? 359.707 338.008 465.626 1.00 78.22  ? 212 MET B O   1 
ATOM 4935 C CB  . MET D 4 212 ? 357.181 337.419 463.957 1.00 78.22  ? 212 MET B CB  1 
ATOM 4936 C CG  . MET D 4 212 ? 356.178 337.443 462.817 1.00 78.22  ? 212 MET B CG  1 
ATOM 4937 S SD  . MET D 4 212 ? 355.362 335.866 462.589 1.00 78.22  ? 212 MET B SD  1 
ATOM 4938 C CE  . MET D 4 212 ? 356.713 334.918 461.905 1.00 78.22  ? 212 MET B CE  1 
ATOM 4939 N N   . ASP D 4 213 ? 358.128 339.360 466.506 1.00 76.36  ? 213 ASP B N   1 
ATOM 4940 C CA  . ASP D 4 213 ? 358.831 339.611 467.752 1.00 76.36  ? 213 ASP B CA  1 
ATOM 4941 C C   . ASP D 4 213 ? 358.017 339.078 468.918 1.00 76.36  ? 213 ASP B C   1 
ATOM 4942 O O   . ASP D 4 213 ? 356.882 338.630 468.758 1.00 76.36  ? 213 ASP B O   1 
ATOM 4943 C CB  . ASP D 4 213 ? 359.086 341.110 467.935 1.00 76.36  ? 213 ASP B CB  1 
ATOM 4944 C CG  . ASP D 4 213 ? 360.359 341.402 468.691 1.00 76.36  ? 213 ASP B CG  1 
ATOM 4945 O OD1 . ASP D 4 213 ? 361.216 340.502 468.788 1.00 76.36  ? 213 ASP B OD1 1 
ATOM 4946 O OD2 . ASP D 4 213 ? 360.499 342.538 469.189 1.00 76.36  ? 213 ASP B OD2 1 
ATOM 4947 N N   . ASN D 4 214 ? 358.624 339.117 470.099 1.00 76.85  ? 214 ASN B N   1 
ATOM 4948 C CA  . ASN D 4 214 ? 357.868 338.931 471.326 1.00 76.85  ? 214 ASN B CA  1 
ATOM 4949 C C   . ASN D 4 214 ? 357.100 340.206 471.633 1.00 76.85  ? 214 ASN B C   1 
ATOM 4950 O O   . ASN D 4 214 ? 357.667 341.298 471.656 1.00 76.85  ? 214 ASN B O   1 
ATOM 4951 C CB  . ASN D 4 214 ? 358.798 338.585 472.484 1.00 76.85  ? 214 ASN B CB  1 
ATOM 4952 C CG  . ASN D 4 214 ? 358.093 337.838 473.591 1.00 76.85  ? 214 ASN B CG  1 
ATOM 4953 O OD1 . ASN D 4 214 ? 357.118 338.322 474.159 1.00 76.85  ? 214 ASN B OD1 1 
ATOM 4954 N ND2 . ASN D 4 214 ? 358.597 336.661 473.923 1.00 76.85  ? 214 ASN B ND2 1 
ATOM 4955 N N   . MET D 4 215 ? 355.804 340.075 471.857 1.00 77.84  ? 215 MET B N   1 
ATOM 4956 C CA  . MET D 4 215 ? 354.958 341.244 472.014 1.00 77.84  ? 215 MET B CA  1 
ATOM 4957 C C   . MET D 4 215 ? 354.701 341.603 473.466 1.00 77.84  ? 215 MET B C   1 
ATOM 4958 O O   . MET D 4 215 ? 353.985 342.571 473.730 1.00 77.84  ? 215 MET B O   1 
ATOM 4959 C CB  . MET D 4 215 ? 353.628 341.024 471.302 1.00 77.84  ? 215 MET B CB  1 
ATOM 4960 C CG  . MET D 4 215 ? 353.771 340.554 469.871 1.00 77.84  ? 215 MET B CG  1 
ATOM 4961 S SD  . MET D 4 215 ? 352.209 340.553 469.001 1.00 77.84  ? 215 MET B SD  1 
ATOM 4962 C CE  . MET D 4 215 ? 351.709 342.258 469.217 1.00 77.84  ? 215 MET B CE  1 
ATOM 4963 N N   . PHE D 4 216 ? 355.256 340.853 474.410 1.00 74.31  ? 216 PHE B N   1 
ATOM 4964 C CA  . PHE D 4 216 ? 355.156 341.211 475.817 1.00 74.31  ? 216 PHE B CA  1 
ATOM 4965 C C   . PHE D 4 216 ? 356.437 341.802 476.362 1.00 74.31  ? 216 PHE B C   1 
ATOM 4966 O O   . PHE D 4 216 ? 356.417 342.436 477.419 1.00 74.31  ? 216 PHE B O   1 
ATOM 4967 C CB  . PHE D 4 216 ? 354.786 339.993 476.662 1.00 74.31  ? 216 PHE B CB  1 
ATOM 4968 C CG  . PHE D 4 216 ? 353.322 339.735 476.727 1.00 74.31  ? 216 PHE B CG  1 
ATOM 4969 C CD1 . PHE D 4 216 ? 352.510 340.494 477.553 1.00 74.31  ? 216 PHE B CD1 1 
ATOM 4970 C CD2 . PHE D 4 216 ? 352.751 338.740 475.949 1.00 74.31  ? 216 PHE B CD2 1 
ATOM 4971 C CE1 . PHE D 4 216 ? 351.150 340.262 477.605 1.00 74.31  ? 216 PHE B CE1 1 
ATOM 4972 C CE2 . PHE D 4 216 ? 351.404 338.503 475.998 1.00 74.31  ? 216 PHE B CE2 1 
ATOM 4973 C CZ  . PHE D 4 216 ? 350.598 339.265 476.825 1.00 74.31  ? 216 PHE B CZ  1 
ATOM 4974 N N   . ARG D 4 217 ? 357.550 341.602 475.668 1.00 62.48  ? 217 ARG B N   1 
ATOM 4975 C CA  . ARG D 4 217 ? 358.838 342.105 476.106 1.00 62.48  ? 217 ARG B CA  1 
ATOM 4976 C C   . ARG D 4 217 ? 359.423 343.111 475.127 1.00 62.48  ? 217 ARG B C   1 
ATOM 4977 O O   . ARG D 4 217 ? 360.644 343.225 475.020 1.00 62.48  ? 217 ARG B O   1 
ATOM 4978 C CB  . ARG D 4 217 ? 359.801 340.942 476.326 1.00 62.48  ? 217 ARG B CB  1 
ATOM 4979 C CG  . ARG D 4 217 ? 359.558 340.221 477.630 1.00 62.48  ? 217 ARG B CG  1 
ATOM 4980 C CD  . ARG D 4 217 ? 360.232 338.873 477.680 1.00 62.48  ? 217 ARG B CD  1 
ATOM 4981 N NE  . ARG D 4 217 ? 359.970 338.201 478.946 1.00 62.48  ? 217 ARG B NE  1 
ATOM 4982 C CZ  . ARG D 4 217 ? 360.905 337.647 479.705 1.00 62.48  ? 217 ARG B CZ  1 
ATOM 4983 N NH1 . ARG D 4 217 ? 362.172 337.673 479.326 1.00 62.48  ? 217 ARG B NH1 1 
ATOM 4984 N NH2 . ARG D 4 217 ? 360.573 337.058 480.842 1.00 62.48  ? 217 ARG B NH2 1 
ATOM 4985 N N   . HIS D 4 218 ? 358.577 343.849 474.417 1.00 57.90  ? 218 HIS B N   1 
ATOM 4986 C CA  . HIS D 4 218 ? 359.066 344.822 473.448 1.00 57.90  ? 218 HIS B CA  1 
ATOM 4987 C C   . HIS D 4 218 ? 357.992 345.871 473.225 1.00 57.90  ? 218 HIS B C   1 
ATOM 4988 O O   . HIS D 4 218 ? 356.840 345.524 472.958 1.00 57.90  ? 218 HIS B O   1 
ATOM 4989 C CB  . HIS D 4 218 ? 359.424 344.147 472.134 1.00 57.90  ? 218 HIS B CB  1 
ATOM 4990 C CG  . HIS D 4 218 ? 360.403 344.920 471.313 1.00 57.90  ? 218 HIS B CG  1 
ATOM 4991 N ND1 . HIS D 4 218 ? 360.465 344.821 469.942 1.00 57.90  ? 218 HIS B ND1 1 
ATOM 4992 C CD2 . HIS D 4 218 ? 361.373 345.791 471.673 1.00 57.90  ? 218 HIS B CD2 1 
ATOM 4993 C CE1 . HIS D 4 218 ? 361.419 345.614 469.491 1.00 57.90  ? 218 HIS B CE1 1 
ATOM 4994 N NE2 . HIS D 4 218 ? 361.987 346.212 470.521 1.00 57.90  ? 218 HIS B NE2 1 
ATOM 4995 N N   . ASN D 4 219 ? 358.365 347.140 473.334 1.00 55.13  ? 219 ASN B N   1 
ATOM 4996 C CA  . ASN D 4 219 ? 357.515 348.266 472.960 1.00 55.13  ? 219 ASN B CA  1 
ATOM 4997 C C   . ASN D 4 219 ? 358.241 349.003 471.846 1.00 55.13  ? 219 ASN B C   1 
ATOM 4998 O O   . ASN D 4 219 ? 359.125 349.820 472.113 1.00 55.13  ? 219 ASN B O   1 
ATOM 4999 C CB  . ASN D 4 219 ? 357.254 349.185 474.143 1.00 55.13  ? 219 ASN B CB  1 
ATOM 5000 C CG  . ASN D 4 219 ? 357.001 348.431 475.416 1.00 55.13  ? 219 ASN B CG  1 
ATOM 5001 O OD1 . ASN D 4 219 ? 356.064 347.643 475.506 1.00 55.13  ? 219 ASN B OD1 1 
ATOM 5002 N ND2 . ASN D 4 219 ? 357.836 348.665 476.417 1.00 55.13  ? 219 ASN B ND2 1 
ATOM 5003 N N   . ASN D 4 220 ? 357.875 348.730 470.602 1.00 55.21  ? 220 ASN B N   1 
ATOM 5004 C CA  . ASN D 4 220 ? 358.651 349.208 469.469 1.00 55.21  ? 220 ASN B CA  1 
ATOM 5005 C C   . ASN D 4 220 ? 358.266 350.608 469.008 1.00 55.21  ? 220 ASN B C   1 
ATOM 5006 O O   . ASN D 4 220 ? 358.789 351.065 467.990 1.00 55.21  ? 220 ASN B O   1 
ATOM 5007 C CB  . ASN D 4 220 ? 358.525 348.231 468.305 1.00 55.21  ? 220 ASN B CB  1 
ATOM 5008 C CG  . ASN D 4 220 ? 357.115 347.782 468.091 1.00 55.21  ? 220 ASN B CG  1 
ATOM 5009 O OD1 . ASN D 4 220 ? 356.207 348.226 468.784 1.00 55.21  ? 220 ASN B OD1 1 
ATOM 5010 N ND2 . ASN D 4 220 ? 356.914 346.897 467.129 1.00 55.21  ? 220 ASN B ND2 1 
ATOM 5011 N N   . LEU D 4 221 ? 357.381 351.299 469.723 1.00 54.24  ? 221 LEU B N   1 
ATOM 5012 C CA  . LEU D 4 221 ? 357.047 352.680 469.401 1.00 54.24  ? 221 LEU B CA  1 
ATOM 5013 C C   . LEU D 4 221 ? 356.790 353.442 470.689 1.00 54.24  ? 221 LEU B C   1 
ATOM 5014 O O   . LEU D 4 221 ? 356.446 352.861 471.717 1.00 54.24  ? 221 LEU B O   1 
ATOM 5015 C CB  . LEU D 4 221 ? 355.824 352.776 468.490 1.00 54.24  ? 221 LEU B CB  1 
ATOM 5016 C CG  . LEU D 4 221 ? 356.035 352.623 466.986 1.00 54.24  ? 221 LEU B CG  1 
ATOM 5017 C CD1 . LEU D 4 221 ? 354.761 352.945 466.242 1.00 54.24  ? 221 LEU B CD1 1 
ATOM 5018 C CD2 . LEU D 4 221 ? 357.158 353.501 466.498 1.00 54.24  ? 221 LEU B CD2 1 
ATOM 5019 N N   . THR D 4 222 ? 356.957 354.758 470.623 1.00 48.73  ? 222 THR B N   1 
ATOM 5020 C CA  . THR D 4 222 ? 356.710 355.620 471.772 1.00 48.73  ? 222 THR B CA  1 
ATOM 5021 C C   . THR D 4 222 ? 356.224 356.961 471.257 1.00 48.73  ? 222 THR B C   1 
ATOM 5022 O O   . THR D 4 222 ? 356.934 357.618 470.496 1.00 48.73  ? 222 THR B O   1 
ATOM 5023 C CB  . THR D 4 222 ? 357.968 355.801 472.613 1.00 48.73  ? 222 THR B CB  1 
ATOM 5024 O OG1 . THR D 4 222 ? 358.375 354.538 473.143 1.00 48.73  ? 222 THR B OG1 1 
ATOM 5025 C CG2 . THR D 4 222 ? 357.710 356.747 473.757 1.00 48.73  ? 222 THR B CG2 1 
ATOM 5026 N N   . LEU D 4 223 ? 355.029 357.360 471.661 1.00 45.71  ? 223 LEU B N   1 
ATOM 5027 C CA  . LEU D 4 223 ? 354.422 358.608 471.217 1.00 45.71  ? 223 LEU B CA  1 
ATOM 5028 C C   . LEU D 4 223 ? 354.577 359.638 472.325 1.00 45.71  ? 223 LEU B C   1 
ATOM 5029 O O   . LEU D 4 223 ? 354.057 359.448 473.425 1.00 45.71  ? 223 LEU B O   1 
ATOM 5030 C CB  . LEU D 4 223 ? 352.952 358.392 470.877 1.00 45.71  ? 223 LEU B CB  1 
ATOM 5031 C CG  . LEU D 4 223 ? 352.095 359.635 470.679 1.00 45.71  ? 223 LEU B CG  1 
ATOM 5032 C CD1 . LEU D 4 223 ? 352.366 360.240 469.338 1.00 45.71  ? 223 LEU B CD1 1 
ATOM 5033 C CD2 . LEU D 4 223 ? 350.638 359.285 470.809 1.00 45.71  ? 223 LEU B CD2 1 
ATOM 5034 N N   . MET D 4 224 ? 355.281 360.727 472.041 1.00 45.44  ? 224 MET B N   1 
ATOM 5035 C CA  . MET D 4 224 ? 355.491 361.791 473.008 1.00 45.44  ? 224 MET B CA  1 
ATOM 5036 C C   . MET D 4 224 ? 354.784 363.058 472.558 1.00 45.44  ? 224 MET B C   1 
ATOM 5037 O O   . MET D 4 224 ? 354.617 363.296 471.362 1.00 45.44  ? 224 MET B O   1 
ATOM 5038 C CB  . MET D 4 224 ? 356.973 362.087 473.196 1.00 45.44  ? 224 MET B CB  1 
ATOM 5039 C CG  . MET D 4 224 ? 357.831 360.877 473.402 1.00 45.44  ? 224 MET B CG  1 
ATOM 5040 S SD  . MET D 4 224 ? 359.569 361.317 473.375 1.00 45.44  ? 224 MET B SD  1 
ATOM 5041 C CE  . MET D 4 224 ? 360.284 359.890 474.174 1.00 45.44  ? 224 MET B CE  1 
ATOM 5042 N N   . ILE D 4 225 ? 354.374 363.867 473.527 1.00 42.80  ? 225 ILE B N   1 
ATOM 5043 C CA  . ILE D 4 225 ? 353.753 365.163 473.290 1.00 42.80  ? 225 ILE B CA  1 
ATOM 5044 C C   . ILE D 4 225 ? 354.434 366.141 474.234 1.00 42.80  ? 225 ILE B C   1 
ATOM 5045 O O   . ILE D 4 225 ? 354.346 365.984 475.455 1.00 42.80  ? 225 ILE B O   1 
ATOM 5046 C CB  . ILE D 4 225 ? 352.239 365.133 473.531 1.00 42.80  ? 225 ILE B CB  1 
ATOM 5047 C CG1 . ILE D 4 225 ? 351.533 364.357 472.427 1.00 42.80  ? 225 ILE B CG1 1 
ATOM 5048 C CG2 . ILE D 4 225 ? 351.692 366.527 473.592 1.00 42.80  ? 225 ILE B CG2 1 
ATOM 5049 C CD1 . ILE D 4 225 ? 350.048 364.292 472.590 1.00 42.80  ? 225 ILE B CD1 1 
ATOM 5050 N N   . ILE D 4 226 ? 355.138 367.123 473.684 1.00 43.44  ? 226 ILE B N   1 
ATOM 5051 C CA  . ILE D 4 226 ? 355.924 368.058 474.477 1.00 43.44  ? 226 ILE B CA  1 
ATOM 5052 C C   . ILE D 4 226 ? 355.486 369.476 474.139 1.00 43.44  ? 226 ILE B C   1 
ATOM 5053 O O   . ILE D 4 226 ? 355.585 369.891 472.983 1.00 43.44  ? 226 ILE B O   1 
ATOM 5054 C CB  . ILE D 4 226 ? 357.434 367.902 474.240 1.00 43.44  ? 226 ILE B CB  1 
ATOM 5055 C CG1 . ILE D 4 226 ? 357.891 366.477 474.533 1.00 43.44  ? 226 ILE B CG1 1 
ATOM 5056 C CG2 . ILE D 4 226 ? 358.192 368.873 475.107 1.00 43.44  ? 226 ILE B CG2 1 
ATOM 5057 C CD1 . ILE D 4 226 ? 359.309 366.208 474.140 1.00 43.44  ? 226 ILE B CD1 1 
ATOM 5058 N N   . PRO D 4 227 ? 355.015 370.261 475.101 1.00 42.54  ? 227 PRO B N   1 
ATOM 5059 C CA  . PRO D 4 227 ? 354.656 371.657 474.831 1.00 42.54  ? 227 PRO B CA  1 
ATOM 5060 C C   . PRO D 4 227 ? 355.892 372.538 474.815 1.00 42.54  ? 227 PRO B C   1 
ATOM 5061 O O   . PRO D 4 227 ? 356.462 372.850 475.865 1.00 42.54  ? 227 PRO B O   1 
ATOM 5062 C CB  . PRO D 4 227 ? 353.725 372.003 476.000 1.00 42.54  ? 227 PRO B CB  1 
ATOM 5063 C CG  . PRO D 4 227 ? 353.571 370.748 476.790 1.00 42.54  ? 227 PRO B CG  1 
ATOM 5064 C CD  . PRO D 4 227 ? 354.732 369.904 476.491 1.00 42.54  ? 227 PRO B CD  1 
ATOM 5065 N N   . PHE D 4 228 ? 356.303 372.959 473.620 1.00 42.62  ? 228 PHE B N   1 
ATOM 5066 C CA  . PHE D 4 228 ? 357.481 373.806 473.508 1.00 42.62  ? 228 PHE B CA  1 
ATOM 5067 C C   . PHE D 4 228 ? 357.193 375.212 474.002 1.00 42.62  ? 228 PHE B C   1 
ATOM 5068 O O   . PHE D 4 228 ? 357.875 375.710 474.900 1.00 42.62  ? 228 PHE B O   1 
ATOM 5069 C CB  . PHE D 4 228 ? 357.976 373.831 472.069 1.00 42.62  ? 228 PHE B CB  1 
ATOM 5070 C CG  . PHE D 4 228 ? 359.100 372.883 471.811 1.00 42.62  ? 228 PHE B CG  1 
ATOM 5071 C CD1 . PHE D 4 228 ? 358.856 371.538 471.626 1.00 42.62  ? 228 PHE B CD1 1 
ATOM 5072 C CD2 . PHE D 4 228 ? 360.403 373.333 471.772 1.00 42.62  ? 228 PHE B CD2 1 
ATOM 5073 C CE1 . PHE D 4 228 ? 359.887 370.667 471.399 1.00 42.62  ? 228 PHE B CE1 1 
ATOM 5074 C CE2 . PHE D 4 228 ? 361.430 372.464 471.543 1.00 42.62  ? 228 PHE B CE2 1 
ATOM 5075 C CZ  . PHE D 4 228 ? 361.171 371.131 471.356 1.00 42.62  ? 228 PHE B CZ  1 
ATOM 5076 N N   . VAL D 4 229 ? 356.185 375.863 473.440 1.00 43.45  ? 229 VAL B N   1 
ATOM 5077 C CA  . VAL D 4 229 ? 355.694 377.141 473.943 1.00 43.45  ? 229 VAL B CA  1 
ATOM 5078 C C   . VAL D 4 229 ? 354.516 376.851 474.864 1.00 43.45  ? 229 VAL B C   1 
ATOM 5079 O O   . VAL D 4 229 ? 353.533 376.249 474.412 1.00 43.45  ? 229 VAL B O   1 
ATOM 5080 C CB  . VAL D 4 229 ? 355.283 378.079 472.805 1.00 43.45  ? 229 VAL B CB  1 
ATOM 5081 C CG1 . VAL D 4 229 ? 354.625 379.304 473.373 1.00 43.45  ? 229 VAL B CG1 1 
ATOM 5082 C CG2 . VAL D 4 229 ? 356.492 378.463 472.004 1.00 43.45  ? 229 VAL B CG2 1 
ATOM 5083 N N   . PRO D 4 230 ? 354.572 377.238 476.133 1.00 44.40  ? 230 PRO B N   1 
ATOM 5084 C CA  . PRO D 4 230 ? 353.546 376.826 477.090 1.00 44.40  ? 230 PRO B CA  1 
ATOM 5085 C C   . PRO D 4 230 ? 352.220 377.526 476.835 1.00 44.40  ? 230 PRO B C   1 
ATOM 5086 O O   . PRO D 4 230 ? 352.133 378.502 476.095 1.00 44.40  ? 230 PRO B O   1 
ATOM 5087 C CB  . PRO D 4 230 ? 354.140 377.246 478.435 1.00 44.40  ? 230 PRO B CB  1 
ATOM 5088 C CG  . PRO D 4 230 ? 355.033 378.358 478.105 1.00 44.40  ? 230 PRO B CG  1 
ATOM 5089 C CD  . PRO D 4 230 ? 355.622 378.038 476.776 1.00 44.40  ? 230 PRO B CD  1 
ATOM 5090 N N   . LEU D 4 231 ? 351.177 376.983 477.448 1.00 45.37  ? 231 LEU B N   1 
ATOM 5091 C CA  . LEU D 4 231 ? 349.849 377.549 477.301 1.00 45.37  ? 231 LEU B CA  1 
ATOM 5092 C C   . LEU D 4 231 ? 349.779 378.889 478.008 1.00 45.37  ? 231 LEU B C   1 
ATOM 5093 O O   . LEU D 4 231 ? 350.430 379.103 479.030 1.00 45.37  ? 231 LEU B O   1 
ATOM 5094 C CB  . LEU D 4 231 ? 348.805 376.597 477.872 1.00 45.37  ? 231 LEU B CB  1 
ATOM 5095 C CG  . LEU D 4 231 ? 347.334 376.825 477.545 1.00 45.37  ? 231 LEU B CG  1 
ATOM 5096 C CD1 . LEU D 4 231 ? 346.988 376.252 476.205 1.00 45.37  ? 231 LEU B CD1 1 
ATOM 5097 C CD2 . LEU D 4 231 ? 346.495 376.185 478.593 1.00 45.37  ? 231 LEU B CD2 1 
ATOM 5098 N N   . ASN D 4 232 ? 349.007 379.806 477.444 1.00 47.71  ? 232 ASN B N   1 
ATOM 5099 C CA  . ASN D 4 232 ? 348.765 381.084 478.082 1.00 47.71  ? 232 ASN B CA  1 
ATOM 5100 C C   . ASN D 4 232 ? 347.362 381.533 477.720 1.00 47.71  ? 232 ASN B C   1 
ATOM 5101 O O   . ASN D 4 232 ? 346.852 381.211 476.649 1.00 47.71  ? 232 ASN B O   1 
ATOM 5102 C CB  . ASN D 4 232 ? 349.797 382.122 477.660 1.00 47.71  ? 232 ASN B CB  1 
ATOM 5103 C CG  . ASN D 4 232 ? 349.936 383.236 478.660 1.00 47.71  ? 232 ASN B CG  1 
ATOM 5104 O OD1 . ASN D 4 232 ? 349.266 383.246 479.683 1.00 47.71  ? 232 ASN B OD1 1 
ATOM 5105 N ND2 . ASN D 4 232 ? 350.810 384.185 478.371 1.00 47.71  ? 232 ASN B ND2 1 
ATOM 5106 N N   . TYR D 4 233 ? 346.738 382.264 478.634 1.00 49.37  ? 233 TYR B N   1 
ATOM 5107 C CA  . TYR D 4 233 ? 345.375 382.735 478.451 1.00 49.37  ? 233 TYR B CA  1 
ATOM 5108 C C   . TYR D 4 233 ? 345.159 383.926 479.367 1.00 49.37  ? 233 TYR B C   1 
ATOM 5109 O O   . TYR D 4 233 ? 345.949 384.181 480.277 1.00 49.37  ? 233 TYR B O   1 
ATOM 5110 C CB  . TYR D 4 233 ? 344.348 381.636 478.745 1.00 49.37  ? 233 TYR B CB  1 
ATOM 5111 C CG  . TYR D 4 233 ? 344.665 380.797 479.959 1.00 49.37  ? 233 TYR B CG  1 
ATOM 5112 C CD1 . TYR D 4 233 ? 344.322 381.222 481.234 1.00 49.37  ? 233 TYR B CD1 1 
ATOM 5113 C CD2 . TYR D 4 233 ? 345.299 379.576 479.829 1.00 49.37  ? 233 TYR B CD2 1 
ATOM 5114 C CE1 . TYR D 4 233 ? 344.617 380.459 482.339 1.00 49.37  ? 233 TYR B CE1 1 
ATOM 5115 C CE2 . TYR D 4 233 ? 345.599 378.811 480.927 1.00 49.37  ? 233 TYR B CE2 1 
ATOM 5116 C CZ  . TYR D 4 233 ? 345.256 379.253 482.175 1.00 49.37  ? 233 TYR B CZ  1 
ATOM 5117 O OH  . TYR D 4 233 ? 345.555 378.473 483.263 1.00 49.37  ? 233 TYR B OH  1 
ATOM 5118 N N   . SER D 4 234 ? 344.078 384.648 479.118 1.00 55.31  ? 234 SER B N   1 
ATOM 5119 C CA  . SER D 4 234 ? 343.688 385.723 480.008 1.00 55.31  ? 234 SER B CA  1 
ATOM 5120 C C   . SER D 4 234 ? 342.625 385.230 480.979 1.00 55.31  ? 234 SER B C   1 
ATOM 5121 O O   . SER D 4 234 ? 342.025 384.173 480.794 1.00 55.31  ? 234 SER B O   1 
ATOM 5122 C CB  . SER D 4 234 ? 343.178 386.919 479.218 1.00 55.31  ? 234 SER B CB  1 
ATOM 5123 O OG  . SER D 4 234 ? 343.227 388.090 480.009 1.00 55.31  ? 234 SER B OG  1 
ATOM 5124 N N   . GLU D 4 235 ? 342.401 386.009 482.030 1.00 58.83  ? 235 GLU B N   1 
ATOM 5125 C CA  . GLU D 4 235 ? 341.495 385.609 483.096 1.00 58.83  ? 235 GLU B CA  1 
ATOM 5126 C C   . GLU D 4 235 ? 340.056 385.666 482.611 1.00 58.83  ? 235 GLU B C   1 
ATOM 5127 O O   . GLU D 4 235 ? 339.592 386.700 482.125 1.00 58.83  ? 235 GLU B O   1 
ATOM 5128 C CB  . GLU D 4 235 ? 341.679 386.504 484.316 1.00 58.83  ? 235 GLU B CB  1 
ATOM 5129 C CG  . GLU D 4 235 ? 341.197 385.884 485.608 1.00 58.83  ? 235 GLU B CG  1 
ATOM 5130 C CD  . GLU D 4 235 ? 341.350 386.817 486.790 1.00 58.83  ? 235 GLU B CD  1 
ATOM 5131 O OE1 . GLU D 4 235 ? 342.326 386.663 487.553 1.00 58.83  ? 235 GLU B OE1 1 
ATOM 5132 O OE2 . GLU D 4 235 ? 340.496 387.709 486.957 1.00 58.83  ? 235 GLU B OE2 1 
ATOM 5133 N N   . GLY D 4 236 ? 339.349 384.543 482.745 1.00 56.62  ? 236 GLY B N   1 
ATOM 5134 C CA  . GLY D 4 236 ? 338.010 384.375 482.212 1.00 56.62  ? 236 GLY B CA  1 
ATOM 5135 C C   . GLY D 4 236 ? 337.878 383.166 481.311 1.00 56.62  ? 236 GLY B C   1 
ATOM 5136 O O   . GLY D 4 236 ? 336.807 382.558 481.250 1.00 56.62  ? 236 GLY B O   1 
ATOM 5137 N N   . SER D 4 237 ? 338.953 382.798 480.625 1.00 54.23  ? 237 SER B N   1 
ATOM 5138 C CA  . SER D 4 237 ? 338.932 381.631 479.768 1.00 54.23  ? 237 SER B CA  1 
ATOM 5139 C C   . SER D 4 237 ? 339.026 380.362 480.606 1.00 54.23  ? 237 SER B C   1 
ATOM 5140 O O   . SER D 4 237 ? 339.143 380.398 481.832 1.00 54.23  ? 237 SER B O   1 
ATOM 5141 C CB  . SER D 4 237 ? 340.080 381.687 478.767 1.00 54.23  ? 237 SER B CB  1 
ATOM 5142 O OG  . SER D 4 237 ? 339.765 382.535 477.685 1.00 54.23  ? 237 SER B OG  1 
ATOM 5143 N N   . SER D 4 238 ? 338.973 379.230 479.932 1.00 51.94  ? 238 SER B N   1 
ATOM 5144 C CA  . SER D 4 238 ? 339.127 377.964 480.623 1.00 51.94  ? 238 SER B CA  1 
ATOM 5145 C C   . SER D 4 238 ? 340.593 377.759 480.977 1.00 51.94  ? 238 SER B C   1 
ATOM 5146 O O   . SER D 4 238 ? 341.464 378.005 480.141 1.00 51.94  ? 238 SER B O   1 
ATOM 5147 C CB  . SER D 4 238 ? 338.625 376.824 479.755 1.00 51.94  ? 238 SER B CB  1 
ATOM 5148 O OG  . SER D 4 238 ? 337.364 377.136 479.201 1.00 51.94  ? 238 SER B OG  1 
ATOM 5149 N N   . PRO D 4 239 ? 340.908 377.298 482.186 1.00 51.04  ? 239 PRO B N   1 
ATOM 5150 C CA  . PRO D 4 239 ? 342.305 377.138 482.593 1.00 51.04  ? 239 PRO B CA  1 
ATOM 5151 C C   . PRO D 4 239 ? 342.980 375.869 482.099 1.00 51.04  ? 239 PRO B C   1 
ATOM 5152 O O   . PRO D 4 239 ? 344.021 375.501 482.646 1.00 51.04  ? 239 PRO B O   1 
ATOM 5153 C CB  . PRO D 4 239 ? 342.194 377.124 484.120 1.00 51.04  ? 239 PRO B CB  1 
ATOM 5154 C CG  . PRO D 4 239 ? 340.900 376.496 484.362 1.00 51.04  ? 239 PRO B CG  1 
ATOM 5155 C CD  . PRO D 4 239 ? 339.991 377.032 483.301 1.00 51.04  ? 239 PRO B CD  1 
ATOM 5156 N N   . TYR D 4 240 ? 342.432 375.190 481.099 1.00 50.62  ? 240 TYR B N   1 
ATOM 5157 C CA  . TYR D 4 240 ? 342.996 373.951 480.596 1.00 50.62  ? 240 TYR B CA  1 
ATOM 5158 C C   . TYR D 4 240 ? 342.568 373.761 479.150 1.00 50.62  ? 240 TYR B C   1 
ATOM 5159 O O   . TYR D 4 240 ? 341.649 374.419 478.666 1.00 50.62  ? 240 TYR B O   1 
ATOM 5160 C CB  . TYR D 4 240 ? 342.563 372.753 481.454 1.00 50.62  ? 240 TYR B CB  1 
ATOM 5161 C CG  . TYR D 4 240 ? 341.065 372.599 481.607 1.00 50.62  ? 240 TYR B CG  1 
ATOM 5162 C CD1 . TYR D 4 240 ? 340.390 373.214 482.652 1.00 50.62  ? 240 TYR B CD1 1 
ATOM 5163 C CD2 . TYR D 4 240 ? 340.328 371.835 480.714 1.00 50.62  ? 240 TYR B CD2 1 
ATOM 5164 C CE1 . TYR D 4 240 ? 339.026 373.083 482.793 1.00 50.62  ? 240 TYR B CE1 1 
ATOM 5165 C CE2 . TYR D 4 240 ? 338.968 371.701 480.844 1.00 50.62  ? 240 TYR B CE2 1 
ATOM 5166 C CZ  . TYR D 4 240 ? 338.321 372.323 481.886 1.00 50.62  ? 240 TYR B CZ  1 
ATOM 5167 O OH  . TYR D 4 240 ? 336.960 372.180 482.022 1.00 50.62  ? 240 TYR B OH  1 
ATOM 5168 N N   . VAL D 4 241 ? 343.243 372.847 478.465 1.00 44.07  ? 241 VAL B N   1 
ATOM 5169 C CA  . VAL D 4 241 ? 342.917 372.476 477.091 1.00 44.07  ? 241 VAL B CA  1 
ATOM 5170 C C   . VAL D 4 241 ? 343.053 370.963 477.004 1.00 44.07  ? 241 VAL B C   1 
ATOM 5171 O O   . VAL D 4 241 ? 344.094 370.426 477.398 1.00 44.07  ? 241 VAL B O   1 
ATOM 5172 C CB  . VAL D 4 241 ? 343.831 373.187 476.081 1.00 44.07  ? 241 VAL B CB  1 
ATOM 5173 C CG1 . VAL D 4 241 ? 343.860 372.457 474.768 1.00 44.07  ? 241 VAL B CG1 1 
ATOM 5174 C CG2 . VAL D 4 241 ? 343.369 374.595 475.848 1.00 44.07  ? 241 VAL B CG2 1 
ATOM 5175 N N   . PRO D 4 242 ? 342.046 370.231 476.540 1.00 45.80  ? 242 PRO B N   1 
ATOM 5176 C CA  . PRO D 4 242 ? 342.160 368.771 476.513 1.00 45.80  ? 242 PRO B CA  1 
ATOM 5177 C C   . PRO D 4 242 ? 342.720 368.253 475.200 1.00 45.80  ? 242 PRO B C   1 
ATOM 5178 O O   . PRO D 4 242 ? 342.425 368.776 474.127 1.00 45.80  ? 242 PRO B O   1 
ATOM 5179 C CB  . PRO D 4 242 ? 340.716 368.310 476.724 1.00 45.80  ? 242 PRO B CB  1 
ATOM 5180 C CG  . PRO D 4 242 ? 339.901 369.404 476.193 1.00 45.80  ? 242 PRO B CG  1 
ATOM 5181 C CD  . PRO D 4 242 ? 340.668 370.679 476.299 1.00 45.80  ? 242 PRO B CD  1 
ATOM 5182 N N   . ILE D 4 243 ? 343.529 367.201 475.299 1.00 47.09  ? 243 ILE B N   1 
ATOM 5183 C CA  . ILE D 4 243 ? 344.201 366.585 474.160 1.00 47.09  ? 243 ILE B CA  1 
ATOM 5184 C C   . ILE D 4 243 ? 343.736 365.140 474.050 1.00 47.09  ? 243 ILE B C   1 
ATOM 5185 O O   . ILE D 4 243 ? 343.866 364.372 475.007 1.00 47.09  ? 243 ILE B O   1 
ATOM 5186 C CB  . ILE D 4 243 ? 345.729 366.648 474.316 1.00 47.09  ? 243 ILE B CB  1 
ATOM 5187 C CG1 . ILE D 4 243 ? 346.188 368.095 474.438 1.00 47.09  ? 243 ILE B CG1 1 
ATOM 5188 C CG2 . ILE D 4 243 ? 346.413 365.976 473.157 1.00 47.09  ? 243 ILE B CG2 1 
ATOM 5189 C CD1 . ILE D 4 243 ? 347.599 368.236 474.891 1.00 47.09  ? 243 ILE B CD1 1 
ATOM 5190 N N   . THR D 4 244 ? 343.217 364.761 472.887 1.00 49.90  ? 244 THR B N   1 
ATOM 5191 C CA  . THR D 4 244 ? 342.576 363.466 472.707 1.00 49.90  ? 244 THR B CA  1 
ATOM 5192 C C   . THR D 4 244 ? 343.350 362.631 471.701 1.00 49.90  ? 244 THR B C   1 
ATOM 5193 O O   . THR D 4 244 ? 343.535 363.050 470.557 1.00 49.90  ? 244 THR B O   1 
ATOM 5194 C CB  . THR D 4 244 ? 341.135 363.635 472.238 1.00 49.90  ? 244 THR B CB  1 
ATOM 5195 O OG1 . THR D 4 244 ? 340.524 364.702 472.965 1.00 49.90  ? 244 THR B OG1 1 
ATOM 5196 C CG2 . THR D 4 244 ? 340.350 362.369 472.484 1.00 49.90  ? 244 THR B CG2 1 
ATOM 5197 N N   . VAL D 4 245 ? 343.775 361.442 472.119 1.00 52.49  ? 245 VAL B N   1 
ATOM 5198 C CA  . VAL D 4 245 ? 344.601 360.558 471.307 1.00 52.49  ? 245 VAL B CA  1 
ATOM 5199 C C   . VAL D 4 245 ? 343.765 359.365 470.872 1.00 52.49  ? 245 VAL B C   1 
ATOM 5200 O O   . VAL D 4 245 ? 343.116 358.721 471.701 1.00 52.49  ? 245 VAL B O   1 
ATOM 5201 C CB  . VAL D 4 245 ? 345.845 360.095 472.078 1.00 52.49  ? 245 VAL B CB  1 
ATOM 5202 C CG1 . VAL D 4 245 ? 346.828 359.450 471.139 1.00 52.49  ? 245 VAL B CG1 1 
ATOM 5203 C CG2 . VAL D 4 245 ? 346.481 361.263 472.778 1.00 52.49  ? 245 VAL B CG2 1 
ATOM 5204 N N   . THR D 4 246 ? 343.798 359.062 469.578 1.00 58.23  ? 246 THR B N   1 
ATOM 5205 C CA  . THR D 4 246 ? 343.021 357.979 468.987 1.00 58.23  ? 246 THR B CA  1 
ATOM 5206 C C   . THR D 4 246 ? 343.957 357.106 468.171 1.00 58.23  ? 246 THR B C   1 
ATOM 5207 O O   . THR D 4 246 ? 344.630 357.601 467.265 1.00 58.23  ? 246 THR B O   1 
ATOM 5208 C CB  . THR D 4 246 ? 341.898 358.530 468.105 1.00 58.23  ? 246 THR B CB  1 
ATOM 5209 O OG1 . THR D 4 246 ? 340.889 359.135 468.921 1.00 58.23  ? 246 THR B OG1 1 
ATOM 5210 C CG2 . THR D 4 246 ? 341.277 357.443 467.290 1.00 58.23  ? 246 THR B CG2 1 
ATOM 5211 N N   . ILE D 4 247 ? 344.003 355.818 468.486 1.00 62.76  ? 247 ILE B N   1 
ATOM 5212 C CA  . ILE D 4 247 ? 344.924 354.882 467.856 1.00 62.76  ? 247 ILE B CA  1 
ATOM 5213 C C   . ILE D 4 247 ? 344.119 353.846 467.090 1.00 62.76  ? 247 ILE B C   1 
ATOM 5214 O O   . ILE D 4 247 ? 343.135 353.309 467.605 1.00 62.76  ? 247 ILE B O   1 
ATOM 5215 C CB  . ILE D 4 247 ? 345.830 354.204 468.901 1.00 62.76  ? 247 ILE B CB  1 
ATOM 5216 C CG1 . ILE D 4 247 ? 346.499 355.250 469.774 1.00 62.76  ? 247 ILE B CG1 1 
ATOM 5217 C CG2 . ILE D 4 247 ? 346.892 353.367 468.238 1.00 62.76  ? 247 ILE B CG2 1 
ATOM 5218 C CD1 . ILE D 4 247 ? 346.997 354.700 471.058 1.00 62.76  ? 247 ILE B CD1 1 
ATOM 5219 N N   . ALA D 4 248 ? 344.536 353.564 465.860 1.00 67.19  ? 248 ALA B N   1 
ATOM 5220 C CA  . ALA D 4 248 ? 343.867 352.583 465.018 1.00 67.19  ? 248 ALA B CA  1 
ATOM 5221 C C   . ALA D 4 248 ? 344.914 351.621 464.485 1.00 67.19  ? 248 ALA B C   1 
ATOM 5222 O O   . ALA D 4 248 ? 345.802 352.043 463.720 1.00 67.19  ? 248 ALA B O   1 
ATOM 5223 C CB  . ALA D 4 248 ? 343.130 353.256 463.864 1.00 67.19  ? 248 ALA B CB  1 
ATOM 5224 N N   . PRO D 4 249 ? 344.869 350.343 464.848 1.00 71.56  ? 249 PRO B N   1 
ATOM 5225 C CA  . PRO D 4 249 ? 345.860 349.406 464.319 1.00 71.56  ? 249 PRO B CA  1 
ATOM 5226 C C   . PRO D 4 249 ? 345.560 349.080 462.867 1.00 71.56  ? 249 PRO B C   1 
ATOM 5227 O O   . PRO D 4 249 ? 344.402 348.929 462.476 1.00 71.56  ? 249 PRO B O   1 
ATOM 5228 C CB  . PRO D 4 249 ? 345.703 348.180 465.220 1.00 71.56  ? 249 PRO B CB  1 
ATOM 5229 C CG  . PRO D 4 249 ? 344.320 348.250 465.703 1.00 71.56  ? 249 PRO B CG  1 
ATOM 5230 C CD  . PRO D 4 249 ? 343.974 349.702 465.822 1.00 71.56  ? 249 PRO B CD  1 
ATOM 5231 N N   . MET D 4 250 ? 346.611 349.016 462.063 1.00 79.86  ? 250 MET B N   1 
ATOM 5232 C CA  . MET D 4 250 ? 346.532 348.528 460.697 1.00 79.86  ? 250 MET B CA  1 
ATOM 5233 C C   . MET D 4 250 ? 347.462 347.334 460.575 1.00 79.86  ? 250 MET B C   1 
ATOM 5234 O O   . MET D 4 250 ? 348.357 347.170 461.409 1.00 79.86  ? 250 MET B O   1 
ATOM 5235 C CB  . MET D 4 250 ? 346.919 349.611 459.696 1.00 79.86  ? 250 MET B CB  1 
ATOM 5236 C CG  . MET D 4 250 ? 346.067 350.849 459.781 1.00 79.86  ? 250 MET B CG  1 
ATOM 5237 S SD  . MET D 4 250 ? 346.440 352.017 458.466 1.00 79.86  ? 250 MET B SD  1 
ATOM 5238 C CE  . MET D 4 250 ? 344.874 352.875 458.333 1.00 79.86  ? 250 MET B CE  1 
ATOM 5239 N N   . CYS D 4 251 ? 347.212 346.494 459.564 1.00 91.03  ? 251 CYS B N   1 
ATOM 5240 C CA  . CYS D 4 251 ? 348.045 345.350 459.160 1.00 91.03  ? 251 CYS B CA  1 
ATOM 5241 C C   . CYS D 4 251 ? 348.338 344.389 460.321 1.00 91.03  ? 251 CYS B C   1 
ATOM 5242 O O   . CYS D 4 251 ? 349.402 343.775 460.413 1.00 91.03  ? 251 CYS B O   1 
ATOM 5243 C CB  . CYS D 4 251 ? 349.327 345.829 458.456 1.00 91.03  ? 251 CYS B CB  1 
ATOM 5244 S SG  . CYS D 4 251 ? 350.732 346.459 459.428 1.00 91.03  ? 251 CYS B SG  1 
ATOM 5245 N N   . ALA D 4 252 ? 347.341 344.225 461.185 1.00 98.08  ? 252 ALA B N   1 
ATOM 5246 C CA  . ALA D 4 252 ? 347.457 343.372 462.358 1.00 98.08  ? 252 ALA B CA  1 
ATOM 5247 C C   . ALA D 4 252 ? 347.386 341.909 461.950 1.00 98.08  ? 252 ALA B C   1 
ATOM 5248 O O   . ALA D 4 252 ? 346.392 341.463 461.371 1.00 98.08  ? 252 ALA B O   1 
ATOM 5249 C CB  . ALA D 4 252 ? 346.357 343.679 463.375 1.00 98.08  ? 252 ALA B CB  1 
ATOM 5250 N N   . GLU D 4 253 ? 348.443 341.165 462.256 1.00 102.63 ? 253 GLU B N   1 
ATOM 5251 C CA  . GLU D 4 253 ? 348.485 339.750 461.927 1.00 102.63 ? 253 GLU B CA  1 
ATOM 5252 C C   . GLU D 4 253 ? 349.372 339.054 462.942 1.00 102.63 ? 253 GLU B C   1 
ATOM 5253 O O   . GLU D 4 253 ? 350.270 339.672 463.515 1.00 102.63 ? 253 GLU B O   1 
ATOM 5254 C CB  . GLU D 4 253 ? 348.965 339.528 460.484 1.00 102.63 ? 253 GLU B CB  1 
ATOM 5255 C CG  . GLU D 4 253 ? 350.453 339.745 460.174 1.00 102.63 ? 253 GLU B CG  1 
ATOM 5256 C CD  . GLU D 4 253 ? 351.299 338.499 460.383 1.00 102.63 ? 253 GLU B CD  1 
ATOM 5257 O OE1 . GLU D 4 253 ? 350.707 337.412 460.482 1.00 102.63 ? 253 GLU B OE1 1 
ATOM 5258 O OE2 . GLU D 4 253 ? 352.540 338.596 460.429 1.00 102.63 ? 253 GLU B OE2 1 
ATOM 5259 N N   . TYR D 4 254 ? 349.111 337.769 463.165 1.00 105.87 ? 254 TYR B N   1 
ATOM 5260 C CA  . TYR D 4 254 ? 349.751 337.025 464.236 1.00 105.87 ? 254 TYR B CA  1 
ATOM 5261 C C   . TYR D 4 254 ? 350.140 335.633 463.765 1.00 105.87 ? 254 TYR B C   1 
ATOM 5262 O O   . TYR D 4 254 ? 349.526 335.067 462.859 1.00 105.87 ? 254 TYR B O   1 
ATOM 5263 C CB  . TYR D 4 254 ? 348.819 336.898 465.443 1.00 105.87 ? 254 TYR B CB  1 
ATOM 5264 C CG  . TYR D 4 254 ? 348.402 338.229 465.978 1.00 105.87 ? 254 TYR B CG  1 
ATOM 5265 C CD1 . TYR D 4 254 ? 349.274 338.989 466.731 1.00 105.87 ? 254 TYR B CD1 1 
ATOM 5266 C CD2 . TYR D 4 254 ? 347.145 338.736 465.698 1.00 105.87 ? 254 TYR B CD2 1 
ATOM 5267 C CE1 . TYR D 4 254 ? 348.907 340.210 467.207 1.00 105.87 ? 254 TYR B CE1 1 
ATOM 5268 C CE2 . TYR D 4 254 ? 346.766 339.957 466.175 1.00 105.87 ? 254 TYR B CE2 1 
ATOM 5269 C CZ  . TYR D 4 254 ? 347.656 340.692 466.933 1.00 105.87 ? 254 TYR B CZ  1 
ATOM 5270 O OH  . TYR D 4 254 ? 347.297 341.918 467.407 1.00 105.87 ? 254 TYR B OH  1 
ATOM 5271 N N   . ASN D 4 255 ? 351.143 335.071 464.427 1.00 108.86 ? 255 ASN B N   1 
ATOM 5272 C CA  . ASN D 4 255 ? 351.586 333.704 464.191 1.00 108.86 ? 255 ASN B CA  1 
ATOM 5273 C C   . ASN D 4 255 ? 350.898 332.806 465.210 1.00 108.86 ? 255 ASN B C   1 
ATOM 5274 O O   . ASN D 4 255 ? 351.002 333.036 466.419 1.00 108.86 ? 255 ASN B O   1 
ATOM 5275 C CB  . ASN D 4 255 ? 353.101 333.593 464.304 1.00 108.86 ? 255 ASN B CB  1 
ATOM 5276 C CG  . ASN D 4 255 ? 353.694 332.649 463.283 1.00 108.86 ? 255 ASN B CG  1 
ATOM 5277 O OD1 . ASN D 4 255 ? 353.579 332.868 462.079 1.00 108.86 ? 255 ASN B OD1 1 
ATOM 5278 N ND2 . ASN D 4 255 ? 354.328 331.586 463.761 1.00 108.86 ? 255 ASN B ND2 1 
ATOM 5279 N N   . GLY D 4 256 ? 350.202 331.787 464.723 1.00 111.56 ? 256 GLY B N   1 
ATOM 5280 C CA  . GLY D 4 256 ? 349.459 330.921 465.615 1.00 111.56 ? 256 GLY B CA  1 
ATOM 5281 C C   . GLY D 4 256 ? 348.849 329.780 464.841 1.00 111.56 ? 256 GLY B C   1 
ATOM 5282 O O   . GLY D 4 256 ? 349.248 329.478 463.714 1.00 111.56 ? 256 GLY B O   1 
ATOM 5283 N N   . LEU D 4 257 ? 347.873 329.138 465.474 1.00 114.13 ? 257 LEU B N   1 
ATOM 5284 C CA  . LEU D 4 257 ? 347.159 328.019 464.872 1.00 114.13 ? 257 LEU B CA  1 
ATOM 5285 C C   . LEU D 4 257 ? 345.712 328.427 464.604 1.00 114.13 ? 257 LEU B C   1 
ATOM 5286 O O   . LEU D 4 257 ? 345.444 329.273 463.752 1.00 114.13 ? 257 LEU B O   1 
ATOM 5287 C CB  . LEU D 4 257 ? 347.236 326.789 465.786 1.00 114.13 ? 257 LEU B CB  1 
ATOM 5288 C CG  . LEU D 4 257 ? 346.818 325.401 465.296 1.00 114.13 ? 257 LEU B CG  1 
ATOM 5289 C CD1 . LEU D 4 257 ? 347.683 324.363 465.973 1.00 114.13 ? 257 LEU B CD1 1 
ATOM 5290 C CD2 . LEU D 4 257 ? 345.355 325.096 465.580 1.00 114.13 ? 257 LEU B CD2 1 
ATOM 5291 N N   . GLY E 5 1   ? 410.516 328.073 441.624 1.00 58.13  ? 1   GLY C N   1 
ATOM 5292 C CA  . GLY E 5 1   ? 409.152 328.210 441.147 1.00 58.13  ? 1   GLY C CA  1 
ATOM 5293 C C   . GLY E 5 1   ? 408.997 329.455 440.301 1.00 58.13  ? 1   GLY C C   1 
ATOM 5294 O O   . GLY E 5 1   ? 409.860 329.751 439.485 1.00 58.13  ? 1   GLY C O   1 
ATOM 5295 N N   . LEU E 5 2   ? 407.908 330.179 440.481 1.00 55.07  ? 2   LEU C N   1 
ATOM 5296 C CA  . LEU E 5 2   ? 407.802 331.478 439.839 1.00 55.07  ? 2   LEU C CA  1 
ATOM 5297 C C   . LEU E 5 2   ? 408.640 332.483 440.615 1.00 55.07  ? 2   LEU C C   1 
ATOM 5298 O O   . LEU E 5 2   ? 408.585 332.499 441.845 1.00 55.07  ? 2   LEU C O   1 
ATOM 5299 C CB  . LEU E 5 2   ? 406.358 331.939 439.784 1.00 55.07  ? 2   LEU C CB  1 
ATOM 5300 C CG  . LEU E 5 2   ? 406.075 333.114 438.851 1.00 55.07  ? 2   LEU C CG  1 
ATOM 5301 C CD1 . LEU E 5 2   ? 405.999 332.641 437.418 1.00 55.07  ? 2   LEU C CD1 1 
ATOM 5302 C CD2 . LEU E 5 2   ? 404.800 333.815 439.250 1.00 55.07  ? 2   LEU C CD2 1 
ATOM 5303 N N   . PRO E 5 3   ? 409.442 333.312 439.945 1.00 55.65  ? 3   PRO C N   1 
ATOM 5304 C CA  . PRO E 5 3   ? 410.318 334.247 440.664 1.00 55.65  ? 3   PRO C CA  1 
ATOM 5305 C C   . PRO E 5 3   ? 409.579 335.526 441.024 1.00 55.65  ? 3   PRO C C   1 
ATOM 5306 O O   . PRO E 5 3   ? 409.093 336.238 440.145 1.00 55.65  ? 3   PRO C O   1 
ATOM 5307 C CB  . PRO E 5 3   ? 411.446 334.514 439.662 1.00 55.65  ? 3   PRO C CB  1 
ATOM 5308 C CG  . PRO E 5 3   ? 411.249 333.509 438.557 1.00 55.65  ? 3   PRO C CG  1 
ATOM 5309 C CD  . PRO E 5 3   ? 409.795 333.243 438.523 1.00 55.65  ? 3   PRO C CD  1 
ATOM 5310 N N   . VAL E 5 4   ? 409.500 335.821 442.321 1.00 53.71  ? 4   VAL C N   1 
ATOM 5311 C CA  . VAL E 5 4   ? 408.867 337.045 442.797 1.00 53.71  ? 4   VAL C CA  1 
ATOM 5312 C C   . VAL E 5 4   ? 409.884 337.883 443.558 1.00 53.71  ? 4   VAL C C   1 
ATOM 5313 O O   . VAL E 5 4   ? 410.996 337.428 443.838 1.00 53.71  ? 4   VAL C O   1 
ATOM 5314 C CB  . VAL E 5 4   ? 407.644 336.745 443.678 1.00 53.71  ? 4   VAL C CB  1 
ATOM 5315 C CG1 . VAL E 5 4   ? 406.618 335.953 442.909 1.00 53.71  ? 4   VAL C CG1 1 
ATOM 5316 C CG2 . VAL E 5 4   ? 408.065 336.004 444.915 1.00 53.71  ? 4   VAL C CG2 1 
ATOM 5317 N N   . MET E 5 5   ? 409.499 339.104 443.915 1.00 52.36  ? 5   MET C N   1 
ATOM 5318 C CA  . MET E 5 5   ? 410.421 340.083 444.481 1.00 52.36  ? 5   MET C CA  1 
ATOM 5319 C C   . MET E 5 5   ? 409.614 341.005 445.375 1.00 52.36  ? 5   MET C C   1 
ATOM 5320 O O   . MET E 5 5   ? 408.665 341.632 444.904 1.00 52.36  ? 5   MET C O   1 
ATOM 5321 C CB  . MET E 5 5   ? 411.102 340.867 443.368 1.00 52.36  ? 5   MET C CB  1 
ATOM 5322 C CG  . MET E 5 5   ? 412.285 341.714 443.776 1.00 52.36  ? 5   MET C CG  1 
ATOM 5323 S SD  . MET E 5 5   ? 412.870 342.748 442.416 1.00 52.36  ? 5   MET C SD  1 
ATOM 5324 C CE  . MET E 5 5   ? 412.798 341.606 441.038 1.00 52.36  ? 5   MET C CE  1 
ATOM 5325 N N   . THR E 5 6   ? 409.977 341.089 446.650 1.00 47.39  ? 6   THR C N   1 
ATOM 5326 C CA  . THR E 5 6   ? 409.181 341.845 447.605 1.00 47.39  ? 6   THR C CA  1 
ATOM 5327 C C   . THR E 5 6   ? 409.636 343.297 447.673 1.00 47.39  ? 6   THR C C   1 
ATOM 5328 O O   . THR E 5 6   ? 410.792 343.584 447.989 1.00 47.39  ? 6   THR C O   1 
ATOM 5329 C CB  . THR E 5 6   ? 409.267 341.208 448.985 1.00 47.39  ? 6   THR C CB  1 
ATOM 5330 O OG1 . THR E 5 6   ? 410.580 341.401 449.509 1.00 47.39  ? 6   THR C OG1 1 
ATOM 5331 C CG2 . THR E 5 6   ? 408.991 339.737 448.895 1.00 47.39  ? 6   THR C CG2 1 
ATOM 5332 N N   . THR E 5 7   ? 408.717 344.205 447.395 1.00 46.96  ? 7   THR C N   1 
ATOM 5333 C CA  . THR E 5 7   ? 408.947 345.634 447.456 1.00 46.96  ? 7   THR C CA  1 
ATOM 5334 C C   . THR E 5 7   ? 408.906 346.114 448.903 1.00 46.96  ? 7   THR C C   1 
ATOM 5335 O O   . THR E 5 7   ? 408.425 345.397 449.779 1.00 46.96  ? 7   THR C O   1 
ATOM 5336 C CB  . THR E 5 7   ? 407.882 346.342 446.634 1.00 46.96  ? 7   THR C CB  1 
ATOM 5337 O OG1 . THR E 5 7   ? 406.624 346.224 447.302 1.00 46.96  ? 7   THR C OG1 1 
ATOM 5338 C CG2 . THR E 5 7   ? 407.775 345.711 445.267 1.00 46.96  ? 7   THR C CG2 1 
ATOM 5339 N N   . PRO E 5 8   ? 409.433 347.309 449.193 1.00 45.42  ? 8   PRO C N   1 
ATOM 5340 C CA  . PRO E 5 8   ? 409.264 347.869 450.536 1.00 45.42  ? 8   PRO C CA  1 
ATOM 5341 C C   . PRO E 5 8   ? 407.811 348.186 450.846 1.00 45.42  ? 8   PRO C C   1 
ATOM 5342 O O   . PRO E 5 8   ? 406.999 348.432 449.955 1.00 45.42  ? 8   PRO C O   1 
ATOM 5343 C CB  . PRO E 5 8   ? 410.115 349.141 450.498 1.00 45.42  ? 8   PRO C CB  1 
ATOM 5344 C CG  . PRO E 5 8   ? 410.375 349.390 449.081 1.00 45.42  ? 8   PRO C CG  1 
ATOM 5345 C CD  . PRO E 5 8   ? 410.467 348.057 448.464 1.00 45.42  ? 8   PRO C CD  1 
ATOM 5346 N N   . GLY E 5 9   ? 407.494 348.174 452.134 1.00 45.89  ? 9   GLY C N   1 
ATOM 5347 C CA  . GLY E 5 9   ? 406.115 348.235 452.563 1.00 45.89  ? 9   GLY C CA  1 
ATOM 5348 C C   . GLY E 5 9   ? 405.388 346.921 452.413 1.00 45.89  ? 9   GLY C C   1 
ATOM 5349 O O   . GLY E 5 9   ? 404.232 346.902 451.977 1.00 45.89  ? 9   GLY C O   1 
ATOM 5350 N N   . SER E 5 10  ? 406.038 345.807 452.745 1.00 44.42  ? 10  SER C N   1 
ATOM 5351 C CA  . SER E 5 10  ? 405.454 344.493 452.518 1.00 44.42  ? 10  SER C CA  1 
ATOM 5352 C C   . SER E 5 10  ? 404.775 343.924 453.760 1.00 44.42  ? 10  SER C C   1 
ATOM 5353 O O   . SER E 5 10  ? 403.553 343.758 453.772 1.00 44.42  ? 10  SER C O   1 
ATOM 5354 C CB  . SER E 5 10  ? 406.530 343.538 452.003 1.00 44.42  ? 10  SER C CB  1 
ATOM 5355 O OG  . SER E 5 10  ? 407.246 342.986 453.078 1.00 44.42  ? 10  SER C OG  1 
ATOM 5356 N N   . THR E 5 11  ? 405.526 343.643 454.818 1.00 45.69  ? 11  THR C N   1 
ATOM 5357 C CA  . THR E 5 11  ? 404.902 343.066 456.011 1.00 45.69  ? 11  THR C CA  1 
ATOM 5358 C C   . THR E 5 11  ? 404.510 344.137 457.016 1.00 45.69  ? 11  THR C C   1 
ATOM 5359 O O   . THR E 5 11  ? 404.866 344.063 458.189 1.00 45.69  ? 11  THR C O   1 
ATOM 5360 C CB  . THR E 5 11  ? 405.822 342.044 456.665 1.00 45.69  ? 11  THR C CB  1 
ATOM 5361 O OG1 . THR E 5 11  ? 406.849 342.725 457.394 1.00 45.69  ? 11  THR C OG1 1 
ATOM 5362 C CG2 . THR E 5 11  ? 406.442 341.122 455.645 1.00 45.69  ? 11  THR C CG2 1 
ATOM 5363 N N   . GLN E 5 12  ? 403.766 345.140 456.573 1.00 43.84  ? 12  GLN C N   1 
ATOM 5364 C CA  . GLN E 5 12  ? 403.369 346.235 457.438 1.00 43.84  ? 12  GLN C CA  1 
ATOM 5365 C C   . GLN E 5 12  ? 401.857 346.268 457.550 1.00 43.84  ? 12  GLN C C   1 
ATOM 5366 O O   . GLN E 5 12  ? 401.137 345.710 456.720 1.00 43.84  ? 12  GLN C O   1 
ATOM 5367 C CB  . GLN E 5 12  ? 403.883 347.580 456.920 1.00 43.84  ? 12  GLN C CB  1 
ATOM 5368 C CG  . GLN E 5 12  ? 403.376 347.933 455.547 1.00 43.84  ? 12  GLN C CG  1 
ATOM 5369 C CD  . GLN E 5 12  ? 403.401 349.413 455.284 1.00 43.84  ? 12  GLN C CD  1 
ATOM 5370 O OE1 . GLN E 5 12  ? 403.613 350.208 456.191 1.00 43.84  ? 12  GLN C OE1 1 
ATOM 5371 N NE2 . GLN E 5 12  ? 403.185 349.796 454.037 1.00 43.84  ? 12  GLN C NE2 1 
ATOM 5372 N N   . PHE E 5 13  ? 401.384 346.932 458.594 1.00 43.42  ? 13  PHE C N   1 
ATOM 5373 C CA  . PHE E 5 13  ? 399.961 347.095 458.859 1.00 43.42  ? 13  PHE C CA  1 
ATOM 5374 C C   . PHE E 5 13  ? 399.664 348.583 458.802 1.00 43.42  ? 13  PHE C C   1 
ATOM 5375 O O   . PHE E 5 13  ? 399.775 349.280 459.811 1.00 43.42  ? 13  PHE C O   1 
ATOM 5376 C CB  . PHE E 5 13  ? 399.589 346.501 460.209 1.00 43.42  ? 13  PHE C CB  1 
ATOM 5377 C CG  . PHE E 5 13  ? 398.164 346.737 460.608 1.00 43.42  ? 13  PHE C CG  1 
ATOM 5378 C CD1 . PHE E 5 13  ? 397.132 346.501 459.721 1.00 43.42  ? 13  PHE C CD1 1 
ATOM 5379 C CD2 . PHE E 5 13  ? 397.859 347.187 461.875 1.00 43.42  ? 13  PHE C CD2 1 
ATOM 5380 C CE1 . PHE E 5 13  ? 395.830 346.715 460.091 1.00 43.42  ? 13  PHE C CE1 1 
ATOM 5381 C CE2 . PHE E 5 13  ? 396.558 347.398 462.246 1.00 43.42  ? 13  PHE C CE2 1 
ATOM 5382 C CZ  . PHE E 5 13  ? 395.544 347.165 461.353 1.00 43.42  ? 13  PHE C CZ  1 
ATOM 5383 N N   . LEU E 5 14  ? 399.320 349.077 457.626 1.00 47.35  ? 14  LEU C N   1 
ATOM 5384 C CA  . LEU E 5 14  ? 398.782 350.418 457.498 1.00 47.35  ? 14  LEU C CA  1 
ATOM 5385 C C   . LEU E 5 14  ? 397.304 350.334 457.830 1.00 47.35  ? 14  LEU C C   1 
ATOM 5386 O O   . LEU E 5 14  ? 396.586 349.532 457.233 1.00 47.35  ? 14  LEU C O   1 
ATOM 5387 C CB  . LEU E 5 14  ? 398.998 350.952 456.086 1.00 47.35  ? 14  LEU C CB  1 
ATOM 5388 C CG  . LEU E 5 14  ? 398.514 352.355 455.742 1.00 47.35  ? 14  LEU C CG  1 
ATOM 5389 C CD1 . LEU E 5 14  ? 399.001 353.360 456.750 1.00 47.35  ? 14  LEU C CD1 1 
ATOM 5390 C CD2 . LEU E 5 14  ? 399.004 352.727 454.368 1.00 47.35  ? 14  LEU C CD2 1 
ATOM 5391 N N   . THR E 5 15  ? 396.850 351.144 458.790 1.00 48.42  ? 15  THR C N   1 
ATOM 5392 C CA  . THR E 5 15  ? 395.519 350.945 459.357 1.00 48.42  ? 15  THR C CA  1 
ATOM 5393 C C   . THR E 5 15  ? 394.392 351.319 458.409 1.00 48.42  ? 15  THR C C   1 
ATOM 5394 O O   . THR E 5 15  ? 393.238 350.997 458.697 1.00 48.42  ? 15  THR C O   1 
ATOM 5395 C CB  . THR E 5 15  ? 395.346 351.750 460.634 1.00 48.42  ? 15  THR C CB  1 
ATOM 5396 O OG1 . THR E 5 15  ? 395.301 353.139 460.307 1.00 48.42  ? 15  THR C OG1 1 
ATOM 5397 C CG2 . THR E 5 15  ? 396.503 351.510 461.559 1.00 48.42  ? 15  THR C CG2 1 
ATOM 5398 N N   . SER E 5 16  ? 394.687 351.974 457.297 1.00 52.05  ? 16  SER C N   1 
ATOM 5399 C CA  . SER E 5 16  ? 393.681 352.430 456.356 1.00 52.05  ? 16  SER C CA  1 
ATOM 5400 C C   . SER E 5 16  ? 393.849 351.767 455.000 1.00 52.05  ? 16  SER C C   1 
ATOM 5401 O O   . SER E 5 16  ? 393.753 352.420 453.966 1.00 52.05  ? 16  SER C O   1 
ATOM 5402 C CB  . SER E 5 16  ? 393.739 353.943 456.207 1.00 52.05  ? 16  SER C CB  1 
ATOM 5403 O OG  . SER E 5 16  ? 395.047 354.353 455.873 1.00 52.05  ? 16  SER C OG  1 
ATOM 5404 N N   . ASP E 5 17  ? 394.112 350.468 454.976 1.00 59.19  ? 17  ASP C N   1 
ATOM 5405 C CA  . ASP E 5 17  ? 394.258 349.763 453.714 1.00 59.19  ? 17  ASP C CA  1 
ATOM 5406 C C   . ASP E 5 17  ? 392.969 349.026 453.372 1.00 59.19  ? 17  ASP C C   1 
ATOM 5407 O O   . ASP E 5 17  ? 392.082 348.852 454.206 1.00 59.19  ? 17  ASP C O   1 
ATOM 5408 C CB  . ASP E 5 17  ? 395.442 348.798 453.755 1.00 59.19  ? 17  ASP C CB  1 
ATOM 5409 C CG  . ASP E 5 17  ? 395.401 347.856 454.942 1.00 59.19  ? 17  ASP C CG  1 
ATOM 5410 O OD1 . ASP E 5 17  ? 394.508 347.988 455.803 1.00 59.19  ? 17  ASP C OD1 1 
ATOM 5411 O OD2 . ASP E 5 17  ? 396.276 346.970 455.014 1.00 59.19  ? 17  ASP C OD2 1 
ATOM 5412 N N   . ASP E 5 18  ? 392.873 348.573 452.124 1.00 70.33  ? 18  ASP C N   1 
ATOM 5413 C CA  . ASP E 5 18  ? 391.710 347.812 451.668 1.00 70.33  ? 18  ASP C CA  1 
ATOM 5414 C C   . ASP E 5 18  ? 392.272 346.554 451.018 1.00 70.33  ? 18  ASP C C   1 
ATOM 5415 O O   . ASP E 5 18  ? 392.455 346.504 449.800 1.00 70.33  ? 18  ASP C O   1 
ATOM 5416 C CB  . ASP E 5 18  ? 390.849 348.632 450.710 1.00 70.33  ? 18  ASP C CB  1 
ATOM 5417 C CG  . ASP E 5 18  ? 389.543 347.929 450.299 1.00 70.33  ? 18  ASP C CG  1 
ATOM 5418 O OD1 . ASP E 5 18  ? 389.541 346.772 449.827 1.00 70.33  ? 18  ASP C OD1 1 
ATOM 5419 O OD2 . ASP E 5 18  ? 388.486 348.584 450.401 1.00 70.33  ? 18  ASP C OD2 1 
ATOM 5420 N N   . PHE E 5 19  ? 392.522 345.538 451.830 1.00 67.36  ? 19  PHE C N   1 
ATOM 5421 C CA  . PHE E 5 19  ? 393.010 344.261 451.346 1.00 67.36  ? 19  PHE C CA  1 
ATOM 5422 C C   . PHE E 5 19  ? 391.989 343.179 451.653 1.00 67.36  ? 19  PHE C C   1 
ATOM 5423 O O   . PHE E 5 19  ? 391.094 343.355 452.481 1.00 67.36  ? 19  PHE C O   1 
ATOM 5424 C CB  . PHE E 5 19  ? 394.359 343.913 451.976 1.00 67.36  ? 19  PHE C CB  1 
ATOM 5425 C CG  . PHE E 5 19  ? 395.482 344.771 451.498 1.00 67.36  ? 19  PHE C CG  1 
ATOM 5426 C CD1 . PHE E 5 19  ? 395.460 345.315 450.228 1.00 67.36  ? 19  PHE C CD1 1 
ATOM 5427 C CD2 . PHE E 5 19  ? 396.558 345.040 452.317 1.00 67.36  ? 19  PHE C CD2 1 
ATOM 5428 C CE1 . PHE E 5 19  ? 396.490 346.111 449.783 1.00 67.36  ? 19  PHE C CE1 1 
ATOM 5429 C CE2 . PHE E 5 19  ? 397.593 345.834 451.878 1.00 67.36  ? 19  PHE C CE2 1 
ATOM 5430 C CZ  . PHE E 5 19  ? 397.558 346.369 450.609 1.00 67.36  ? 19  PHE C CZ  1 
ATOM 5431 N N   . GLN E 5 20  ? 392.136 342.050 450.971 1.00 63.43  ? 20  GLN C N   1 
ATOM 5432 C CA  . GLN E 5 20  ? 391.320 340.888 451.265 1.00 63.43  ? 20  GLN C CA  1 
ATOM 5433 C C   . GLN E 5 20  ? 391.705 340.294 452.612 1.00 63.43  ? 20  GLN C C   1 
ATOM 5434 O O   . GLN E 5 20  ? 392.742 340.616 453.195 1.00 63.43  ? 20  GLN C O   1 
ATOM 5435 C CB  . GLN E 5 20  ? 391.477 339.837 450.176 1.00 63.43  ? 20  GLN C CB  1 
ATOM 5436 C CG  . GLN E 5 20  ? 390.684 340.126 448.939 1.00 63.43  ? 20  GLN C CG  1 
ATOM 5437 C CD  . GLN E 5 20  ? 389.204 339.994 449.173 1.00 63.43  ? 20  GLN C CD  1 
ATOM 5438 O OE1 . GLN E 5 20  ? 388.426 340.878 448.821 1.00 63.43  ? 20  GLN C OE1 1 
ATOM 5439 N NE2 . GLN E 5 20  ? 388.800 338.883 449.767 1.00 63.43  ? 20  GLN C NE2 1 
ATOM 5440 N N   . SER E 5 21  ? 390.855 339.401 453.104 1.00 57.17  ? 21  SER C N   1 
ATOM 5441 C CA  . SER E 5 21  ? 391.063 338.814 454.401 1.00 57.17  ? 21  SER C CA  1 
ATOM 5442 C C   . SER E 5 21  ? 390.341 337.480 454.439 1.00 57.17  ? 21  SER C C   1 
ATOM 5443 O O   . SER E 5 21  ? 389.236 337.370 453.893 1.00 57.17  ? 21  SER C O   1 
ATOM 5444 C CB  . SER E 5 21  ? 390.548 339.720 455.519 1.00 57.17  ? 21  SER C CB  1 
ATOM 5445 O OG  . SER E 5 21  ? 389.296 340.275 455.177 1.00 57.17  ? 21  SER C OG  1 
ATOM 5446 N N   . PRO E 5 22  ? 390.928 336.459 455.056 1.00 54.69  ? 22  PRO C N   1 
ATOM 5447 C CA  . PRO E 5 22  ? 390.257 335.157 455.111 1.00 54.69  ? 22  PRO C CA  1 
ATOM 5448 C C   . PRO E 5 22  ? 389.140 335.178 456.141 1.00 54.69  ? 22  PRO C C   1 
ATOM 5449 O O   . PRO E 5 22  ? 389.279 335.765 457.213 1.00 54.69  ? 22  PRO C O   1 
ATOM 5450 C CB  . PRO E 5 22  ? 391.381 334.197 455.506 1.00 54.69  ? 22  PRO C CB  1 
ATOM 5451 C CG  . PRO E 5 22  ? 392.353 335.043 456.230 1.00 54.69  ? 22  PRO C CG  1 
ATOM 5452 C CD  . PRO E 5 22  ? 392.260 336.427 455.678 1.00 54.69  ? 22  PRO C CD  1 
ATOM 5453 N N   . SER E 5 23  ? 388.026 334.540 455.805 1.00 53.22  ? 23  SER C N   1 
ATOM 5454 C CA  . SER E 5 23  ? 386.863 334.573 456.677 1.00 53.22  ? 23  SER C CA  1 
ATOM 5455 C C   . SER E 5 23  ? 387.042 333.599 457.830 1.00 53.22  ? 23  SER C C   1 
ATOM 5456 O O   . SER E 5 23  ? 387.516 332.478 457.637 1.00 53.22  ? 23  SER C O   1 
ATOM 5457 C CB  . SER E 5 23  ? 385.601 334.241 455.887 1.00 53.22  ? 23  SER C CB  1 
ATOM 5458 O OG  . SER E 5 23  ? 384.456 334.303 456.714 1.00 53.22  ? 23  SER C OG  1 
ATOM 5459 N N   . ALA E 5 24  ? 386.670 334.032 459.034 1.00 52.62  ? 24  ALA C N   1 
ATOM 5460 C CA  . ALA E 5 24  ? 386.849 333.184 460.205 1.00 52.62  ? 24  ALA C CA  1 
ATOM 5461 C C   . ALA E 5 24  ? 385.846 332.049 460.219 1.00 52.62  ? 24  ALA C C   1 
ATOM 5462 O O   . ALA E 5 24  ? 386.201 330.903 460.506 1.00 52.62  ? 24  ALA C O   1 
ATOM 5463 C CB  . ALA E 5 24  ? 386.729 334.003 461.485 1.00 52.62  ? 24  ALA C CB  1 
ATOM 5464 N N   . MET E 5 25  ? 384.587 332.347 459.918 1.00 56.53  ? 25  MET C N   1 
ATOM 5465 C CA  . MET E 5 25  ? 383.531 331.343 459.851 1.00 56.53  ? 25  MET C CA  1 
ATOM 5466 C C   . MET E 5 25  ? 383.006 331.287 458.427 1.00 56.53  ? 25  MET C C   1 
ATOM 5467 O O   . MET E 5 25  ? 382.060 332.006 458.078 1.00 56.53  ? 25  MET C O   1 
ATOM 5468 C CB  . MET E 5 25  ? 382.404 331.655 460.827 1.00 56.53  ? 25  MET C CB  1 
ATOM 5469 C CG  . MET E 5 25  ? 382.825 331.644 462.267 1.00 56.53  ? 25  MET C CG  1 
ATOM 5470 S SD  . MET E 5 25  ? 381.405 331.716 463.358 1.00 56.53  ? 25  MET C SD  1 
ATOM 5471 C CE  . MET E 5 25  ? 380.444 330.350 462.725 1.00 56.53  ? 25  MET C CE  1 
ATOM 5472 N N   . PRO E 5 26  ? 383.574 330.448 457.576 1.00 58.52  ? 26  PRO C N   1 
ATOM 5473 C CA  . PRO E 5 26  ? 382.913 330.096 456.324 1.00 58.52  ? 26  PRO C CA  1 
ATOM 5474 C C   . PRO E 5 26  ? 381.851 329.048 456.626 1.00 58.52  ? 26  PRO C C   1 
ATOM 5475 O O   . PRO E 5 26  ? 381.658 328.662 457.775 1.00 58.52  ? 26  PRO C O   1 
ATOM 5476 C CB  . PRO E 5 26  ? 384.048 329.531 455.482 1.00 58.52  ? 26  PRO C CB  1 
ATOM 5477 C CG  . PRO E 5 26  ? 384.943 328.912 456.472 1.00 58.52  ? 26  PRO C CG  1 
ATOM 5478 C CD  . PRO E 5 26  ? 384.831 329.705 457.747 1.00 58.52  ? 26  PRO C CD  1 
ATOM 5479 N N   . GLN E 5 27  ? 381.152 328.621 455.569 1.00 64.13  ? 27  GLN C N   1 
ATOM 5480 C CA  . GLN E 5 27  ? 380.075 327.611 455.600 1.00 64.13  ? 27  GLN C CA  1 
ATOM 5481 C C   . GLN E 5 27  ? 379.004 327.897 456.662 1.00 64.13  ? 27  GLN C C   1 
ATOM 5482 O O   . GLN E 5 27  ? 378.335 326.994 457.165 1.00 64.13  ? 27  GLN C O   1 
ATOM 5483 C CB  . GLN E 5 27  ? 380.646 326.179 455.714 1.00 64.13  ? 27  GLN C CB  1 
ATOM 5484 C CG  . GLN E 5 27  ? 381.221 325.653 457.040 1.00 64.13  ? 27  GLN C CG  1 
ATOM 5485 C CD  . GLN E 5 27  ? 382.287 324.602 456.837 1.00 64.13  ? 27  GLN C CD  1 
ATOM 5486 O OE1 . GLN E 5 27  ? 382.607 324.235 455.710 1.00 64.13  ? 27  GLN C OE1 1 
ATOM 5487 N NE2 . GLN E 5 27  ? 382.846 324.114 457.932 1.00 64.13  ? 27  GLN C NE2 1 
ATOM 5488 N N   . PHE E 5 28  ? 378.784 329.179 456.956 1.00 60.67  ? 28  PHE C N   1 
ATOM 5489 C CA  . PHE E 5 28  ? 377.830 329.576 457.981 1.00 60.67  ? 28  PHE C CA  1 
ATOM 5490 C C   . PHE E 5 28  ? 376.456 329.928 457.430 1.00 60.67  ? 28  PHE C C   1 
ATOM 5491 O O   . PHE E 5 28  ? 375.458 329.679 458.116 1.00 60.67  ? 28  PHE C O   1 
ATOM 5492 C CB  . PHE E 5 28  ? 378.368 330.760 458.784 1.00 60.67  ? 28  PHE C CB  1 
ATOM 5493 C CG  . PHE E 5 28  ? 377.409 331.269 459.807 1.00 60.67  ? 28  PHE C CG  1 
ATOM 5494 C CD1 . PHE E 5 28  ? 377.012 330.465 460.853 1.00 60.67  ? 28  PHE C CD1 1 
ATOM 5495 C CD2 . PHE E 5 28  ? 376.875 332.536 459.705 1.00 60.67  ? 28  PHE C CD2 1 
ATOM 5496 C CE1 . PHE E 5 28  ? 376.112 330.923 461.788 1.00 60.67  ? 28  PHE C CE1 1 
ATOM 5497 C CE2 . PHE E 5 28  ? 375.975 332.998 460.636 1.00 60.67  ? 28  PHE C CE2 1 
ATOM 5498 C CZ  . PHE E 5 28  ? 375.594 332.191 461.677 1.00 60.67  ? 28  PHE C CZ  1 
ATOM 5499 N N   . ASP E 5 29  ? 376.386 330.467 456.205 1.00 63.62  ? 29  ASP C N   1 
ATOM 5500 C CA  . ASP E 5 29  ? 375.138 330.782 455.495 1.00 63.62  ? 29  ASP C CA  1 
ATOM 5501 C C   . ASP E 5 29  ? 374.294 331.798 456.275 1.00 63.62  ? 29  ASP C C   1 
ATOM 5502 O O   . ASP E 5 29  ? 373.282 331.472 456.894 1.00 63.62  ? 29  ASP C O   1 
ATOM 5503 C CB  . ASP E 5 29  ? 374.334 329.516 455.166 1.00 63.62  ? 29  ASP C CB  1 
ATOM 5504 C CG  . ASP E 5 29  ? 373.589 329.626 453.854 1.00 63.62  ? 29  ASP C CG  1 
ATOM 5505 O OD1 . ASP E 5 29  ? 373.662 330.695 453.216 1.00 63.62  ? 29  ASP C OD1 1 
ATOM 5506 O OD2 . ASP E 5 29  ? 372.929 328.643 453.458 1.00 63.62  ? 29  ASP C OD2 1 
ATOM 5507 N N   . VAL E 5 30  ? 374.791 333.041 456.256 1.00 56.26  ? 30  VAL C N   1 
ATOM 5508 C CA  . VAL E 5 30  ? 374.222 334.142 457.032 1.00 56.26  ? 30  VAL C CA  1 
ATOM 5509 C C   . VAL E 5 30  ? 372.772 334.440 456.648 1.00 56.26  ? 30  VAL C C   1 
ATOM 5510 O O   . VAL E 5 30  ? 372.263 334.011 455.607 1.00 56.26  ? 30  VAL C O   1 
ATOM 5511 C CB  . VAL E 5 30  ? 375.080 335.404 456.863 1.00 56.26  ? 30  VAL C CB  1 
ATOM 5512 C CG1 . VAL E 5 30  ? 376.521 335.106 457.176 1.00 56.26  ? 30  VAL C CG1 1 
ATOM 5513 C CG2 . VAL E 5 30  ? 374.946 335.944 455.458 1.00 56.26  ? 30  VAL C CG2 1 
ATOM 5514 N N   . THR E 5 31  ? 372.110 335.193 457.518 1.00 52.52  ? 31  THR C N   1 
ATOM 5515 C CA  . THR E 5 31  ? 370.695 335.497 457.358 1.00 52.52  ? 31  THR C CA  1 
ATOM 5516 C C   . THR E 5 31  ? 370.503 336.490 456.220 1.00 52.52  ? 31  THR C C   1 
ATOM 5517 O O   . THR E 5 31  ? 371.199 337.509 456.175 1.00 52.52  ? 31  THR C O   1 
ATOM 5518 C CB  . THR E 5 31  ? 370.148 336.077 458.655 1.00 52.52  ? 31  THR C CB  1 
ATOM 5519 O OG1 . THR E 5 31  ? 370.549 335.250 459.750 1.00 52.52  ? 31  THR C OG1 1 
ATOM 5520 C CG2 . THR E 5 31  ? 368.644 336.127 458.622 1.00 52.52  ? 31  THR C CG2 1 
ATOM 5521 N N   . PRO E 5 32  ? 369.590 336.235 455.288 1.00 54.43  ? 32  PRO C N   1 
ATOM 5522 C CA  . PRO E 5 32  ? 369.384 337.171 454.181 1.00 54.43  ? 32  PRO C CA  1 
ATOM 5523 C C   . PRO E 5 32  ? 368.688 338.439 454.650 1.00 54.43  ? 32  PRO C C   1 
ATOM 5524 O O   . PRO E 5 32  ? 368.114 338.511 455.735 1.00 54.43  ? 32  PRO C O   1 
ATOM 5525 C CB  . PRO E 5 32  ? 368.517 336.378 453.204 1.00 54.43  ? 32  PRO C CB  1 
ATOM 5526 C CG  . PRO E 5 32  ? 367.836 335.384 454.039 1.00 54.43  ? 32  PRO C CG  1 
ATOM 5527 C CD  . PRO E 5 32  ? 368.794 335.012 455.118 1.00 54.43  ? 32  PRO C CD  1 
ATOM 5528 N N   . GLU E 5 33  ? 368.738 339.451 453.791 1.00 56.45  ? 33  GLU C N   1 
ATOM 5529 C CA  . GLU E 5 33  ? 368.333 340.796 454.157 1.00 56.45  ? 33  GLU C CA  1 
ATOM 5530 C C   . GLU E 5 33  ? 366.815 340.930 454.205 1.00 56.45  ? 33  GLU C C   1 
ATOM 5531 O O   . GLU E 5 33  ? 366.064 339.966 454.050 1.00 56.45  ? 33  GLU C O   1 
ATOM 5532 C CB  . GLU E 5 33  ? 368.917 341.807 453.180 1.00 56.45  ? 33  GLU C CB  1 
ATOM 5533 C CG  . GLU E 5 33  ? 370.392 342.031 453.376 1.00 56.45  ? 33  GLU C CG  1 
ATOM 5534 C CD  . GLU E 5 33  ? 370.875 343.291 452.711 1.00 56.45  ? 33  GLU C CD  1 
ATOM 5535 O OE1 . GLU E 5 33  ? 370.059 344.213 452.513 1.00 56.45  ? 33  GLU C OE1 1 
ATOM 5536 O OE2 . GLU E 5 33  ? 372.073 343.354 452.378 1.00 56.45  ? 33  GLU C OE2 1 
ATOM 5537 N N   . MET E 5 34  ? 366.367 342.164 454.412 1.00 58.09  ? 34  MET C N   1 
ATOM 5538 C CA  . MET E 5 34  ? 364.979 342.452 454.721 1.00 58.09  ? 34  MET C CA  1 
ATOM 5539 C C   . MET E 5 34  ? 364.707 343.917 454.415 1.00 58.09  ? 34  MET C C   1 
ATOM 5540 O O   . MET E 5 34  ? 365.585 344.765 454.590 1.00 58.09  ? 34  MET C O   1 
ATOM 5541 C CB  . MET E 5 34  ? 364.702 342.126 456.195 1.00 58.09  ? 34  MET C CB  1 
ATOM 5542 C CG  . MET E 5 34  ? 363.319 342.420 456.731 1.00 58.09  ? 34  MET C CG  1 
ATOM 5543 S SD  . MET E 5 34  ? 363.292 342.097 458.499 1.00 58.09  ? 34  MET C SD  1 
ATOM 5544 C CE  . MET E 5 34  ? 361.921 343.104 459.027 1.00 58.09  ? 34  MET C CE  1 
ATOM 5545 N N   . GLN E 5 35  ? 363.502 344.209 453.937 1.00 57.72  ? 35  GLN C N   1 
ATOM 5546 C CA  . GLN E 5 35  ? 363.065 345.586 453.723 1.00 57.72  ? 35  GLN C CA  1 
ATOM 5547 C C   . GLN E 5 35  ? 362.700 346.207 455.062 1.00 57.72  ? 35  GLN C C   1 
ATOM 5548 O O   . GLN E 5 35  ? 361.653 345.904 455.635 1.00 57.72  ? 35  GLN C O   1 
ATOM 5549 C CB  . GLN E 5 35  ? 361.876 345.621 452.774 1.00 57.72  ? 35  GLN C CB  1 
ATOM 5550 C CG  . GLN E 5 35  ? 362.209 345.296 451.338 1.00 57.72  ? 35  GLN C CG  1 
ATOM 5551 C CD  . GLN E 5 35  ? 363.110 346.333 450.713 1.00 57.72  ? 35  GLN C CD  1 
ATOM 5552 O OE1 . GLN E 5 35  ? 364.247 346.043 450.348 1.00 57.72  ? 35  GLN C OE1 1 
ATOM 5553 N NE2 . GLN E 5 35  ? 362.611 347.557 450.598 1.00 57.72  ? 35  GLN C NE2 1 
ATOM 5554 N N   . ILE E 5 36  ? 363.558 347.080 455.564 1.00 51.91  ? 36  ILE C N   1 
ATOM 5555 C CA  . ILE E 5 36  ? 363.297 347.850 456.777 1.00 51.91  ? 36  ILE C CA  1 
ATOM 5556 C C   . ILE E 5 36  ? 363.124 349.308 456.368 1.00 51.91  ? 36  ILE C C   1 
ATOM 5557 O O   . ILE E 5 36  ? 363.921 349.806 455.564 1.00 51.91  ? 36  ILE C O   1 
ATOM 5558 C CB  . ILE E 5 36  ? 364.442 347.696 457.795 1.00 51.91  ? 36  ILE C CB  1 
ATOM 5559 C CG1 . ILE E 5 36  ? 364.820 346.225 457.948 1.00 51.91  ? 36  ILE C CG1 1 
ATOM 5560 C CG2 . ILE E 5 36  ? 364.059 348.262 459.138 1.00 51.91  ? 36  ILE C CG2 1 
ATOM 5561 C CD1 . ILE E 5 36  ? 365.966 345.980 458.889 1.00 51.91  ? 36  ILE C CD1 1 
ATOM 5562 N N   . PRO E 5 37  ? 362.108 350.010 456.864 1.00 52.15  ? 37  PRO C N   1 
ATOM 5563 C CA  . PRO E 5 37  ? 361.880 351.386 456.412 1.00 52.15  ? 37  PRO C CA  1 
ATOM 5564 C C   . PRO E 5 37  ? 362.891 352.364 456.982 1.00 52.15  ? 37  PRO C C   1 
ATOM 5565 O O   . PRO E 5 37  ? 363.260 352.292 458.153 1.00 52.15  ? 37  PRO C O   1 
ATOM 5566 C CB  . PRO E 5 37  ? 360.474 351.698 456.932 1.00 52.15  ? 37  PRO C CB  1 
ATOM 5567 C CG  . PRO E 5 37  ? 359.860 350.382 457.190 1.00 52.15  ? 37  PRO C CG  1 
ATOM 5568 C CD  . PRO E 5 37  ? 360.962 349.500 457.629 1.00 52.15  ? 37  PRO C CD  1 
ATOM 5569 N N   . GLY E 5 38  ? 363.324 353.296 456.143 1.00 50.20  ? 38  GLY C N   1 
ATOM 5570 C CA  . GLY E 5 38  ? 364.144 354.393 456.609 1.00 50.20  ? 38  GLY C CA  1 
ATOM 5571 C C   . GLY E 5 38  ? 365.628 354.189 456.445 1.00 50.20  ? 38  GLY C C   1 
ATOM 5572 O O   . GLY E 5 38  ? 366.385 354.377 457.397 1.00 50.20  ? 38  GLY C O   1 
ATOM 5573 N N   . ARG E 5 39  ? 366.064 353.817 455.247 1.00 49.92  ? 39  ARG C N   1 
ATOM 5574 C CA  . ARG E 5 39  ? 367.476 353.568 455.006 1.00 49.92  ? 39  ARG C CA  1 
ATOM 5575 C C   . ARG E 5 39  ? 368.201 354.867 454.705 1.00 49.92  ? 39  ARG C C   1 
ATOM 5576 O O   . ARG E 5 39  ? 367.651 355.765 454.067 1.00 49.92  ? 39  ARG C O   1 
ATOM 5577 C CB  . ARG E 5 39  ? 367.661 352.597 453.847 1.00 49.92  ? 39  ARG C CB  1 
ATOM 5578 C CG  . ARG E 5 39  ? 369.008 351.916 453.862 1.00 49.92  ? 39  ARG C CG  1 
ATOM 5579 C CD  . ARG E 5 39  ? 369.195 351.026 452.671 1.00 49.92  ? 39  ARG C CD  1 
ATOM 5580 N NE  . ARG E 5 39  ? 370.603 350.743 452.455 1.00 49.92  ? 39  ARG C NE  1 
ATOM 5581 C CZ  . ARG E 5 39  ? 371.083 350.191 451.350 1.00 49.92  ? 39  ARG C CZ  1 
ATOM 5582 N NH1 . ARG E 5 39  ? 372.382 349.970 451.232 1.00 49.92  ? 39  ARG C NH1 1 
ATOM 5583 N NH2 . ARG E 5 39  ? 370.264 349.865 450.362 1.00 49.92  ? 39  ARG C NH2 1 
ATOM 5584 N N   . VAL E 5 40  ? 369.444 354.961 455.168 1.00 50.09  ? 40  VAL C N   1 
ATOM 5585 C CA  . VAL E 5 40  ? 370.267 356.150 454.998 1.00 50.09  ? 40  VAL C CA  1 
ATOM 5586 C C   . VAL E 5 40  ? 371.409 355.815 454.054 1.00 50.09  ? 40  VAL C C   1 
ATOM 5587 O O   . VAL E 5 40  ? 372.106 354.813 454.243 1.00 50.09  ? 40  VAL C O   1 
ATOM 5588 C CB  . VAL E 5 40  ? 370.811 356.652 456.340 1.00 50.09  ? 40  VAL C CB  1 
ATOM 5589 C CG1 . VAL E 5 40  ? 371.288 358.070 456.210 1.00 50.09  ? 40  VAL C CG1 1 
ATOM 5590 C CG2 . VAL E 5 40  ? 369.760 356.547 457.400 1.00 50.09  ? 40  VAL C CG2 1 
ATOM 5591 N N   . ASN E 5 41  ? 371.610 356.654 453.043 1.00 52.99  ? 41  ASN C N   1 
ATOM 5592 C CA  . ASN E 5 41  ? 372.722 356.480 452.122 1.00 52.99  ? 41  ASN C CA  1 
ATOM 5593 C C   . ASN E 5 41  ? 373.818 357.520 452.289 1.00 52.99  ? 41  ASN C C   1 
ATOM 5594 O O   . ASN E 5 41  ? 374.947 357.274 451.858 1.00 52.99  ? 41  ASN C O   1 
ATOM 5595 C CB  . ASN E 5 41  ? 372.224 356.521 450.677 1.00 52.99  ? 41  ASN C CB  1 
ATOM 5596 C CG  . ASN E 5 41  ? 371.613 355.217 450.238 1.00 52.99  ? 41  ASN C CG  1 
ATOM 5597 O OD1 . ASN E 5 41  ? 372.299 354.342 449.716 1.00 52.99  ? 41  ASN C OD1 1 
ATOM 5598 N ND2 . ASN E 5 41  ? 370.310 355.084 450.429 1.00 52.99  ? 41  ASN C ND2 1 
ATOM 5599 N N   . ASN E 5 42  ? 373.517 358.666 452.890 1.00 52.79  ? 42  ASN C N   1 
ATOM 5600 C CA  . ASN E 5 42  ? 374.470 359.757 453.011 1.00 52.79  ? 42  ASN C CA  1 
ATOM 5601 C C   . ASN E 5 42  ? 374.152 360.537 454.272 1.00 52.79  ? 42  ASN C C   1 
ATOM 5602 O O   . ASN E 5 42  ? 373.018 360.518 454.746 1.00 52.79  ? 42  ASN C O   1 
ATOM 5603 C CB  . ASN E 5 42  ? 374.410 360.675 451.793 1.00 52.79  ? 42  ASN C CB  1 
ATOM 5604 C CG  . ASN E 5 42  ? 375.650 361.514 451.638 1.00 52.79  ? 42  ASN C CG  1 
ATOM 5605 O OD1 . ASN E 5 42  ? 375.910 362.405 452.438 1.00 52.79  ? 42  ASN C OD1 1 
ATOM 5606 N ND2 . ASN E 5 42  ? 376.425 361.239 450.601 1.00 52.79  ? 42  ASN C ND2 1 
ATOM 5607 N N   . LEU E 5 43  ? 375.153 361.224 454.813 1.00 52.63  ? 43  LEU C N   1 
ATOM 5608 C CA  . LEU E 5 43  ? 374.947 361.983 456.039 1.00 52.63  ? 43  LEU C CA  1 
ATOM 5609 C C   . LEU E 5 43  ? 374.270 363.322 455.802 1.00 52.63  ? 43  LEU C C   1 
ATOM 5610 O O   . LEU E 5 43  ? 373.813 363.941 456.764 1.00 52.63  ? 43  LEU C O   1 
ATOM 5611 C CB  . LEU E 5 43  ? 376.276 362.220 456.749 1.00 52.63  ? 43  LEU C CB  1 
ATOM 5612 C CG  . LEU E 5 43  ? 376.663 361.316 457.912 1.00 52.63  ? 43  LEU C CG  1 
ATOM 5613 C CD1 . LEU E 5 43  ? 375.763 361.563 459.099 1.00 52.63  ? 43  LEU C CD1 1 
ATOM 5614 C CD2 . LEU E 5 43  ? 376.611 359.869 457.506 1.00 52.63  ? 43  LEU C CD2 1 
ATOM 5615 N N   . MET E 5 44  ? 374.200 363.790 454.560 1.00 57.99  ? 44  MET C N   1 
ATOM 5616 C CA  . MET E 5 44  ? 373.637 365.108 454.311 1.00 57.99  ? 44  MET C CA  1 
ATOM 5617 C C   . MET E 5 44  ? 372.122 365.116 454.374 1.00 57.99  ? 44  MET C C   1 
ATOM 5618 O O   . MET E 5 44  ? 371.530 366.180 454.566 1.00 57.99  ? 44  MET C O   1 
ATOM 5619 C CB  . MET E 5 44  ? 374.099 365.628 452.958 1.00 57.99  ? 44  MET C CB  1 
ATOM 5620 C CG  . MET E 5 44  ? 375.492 366.188 452.990 1.00 57.99  ? 44  MET C CG  1 
ATOM 5621 S SD  . MET E 5 44  ? 375.612 367.552 454.155 1.00 57.99  ? 44  MET C SD  1 
ATOM 5622 C CE  . MET E 5 44  ? 377.098 367.113 455.043 1.00 57.99  ? 44  MET C CE  1 
ATOM 5623 N N   . GLU E 5 45  ? 371.478 363.966 454.221 1.00 58.34  ? 45  GLU C N   1 
ATOM 5624 C CA  . GLU E 5 45  ? 370.029 363.937 454.328 1.00 58.34  ? 45  GLU C CA  1 
ATOM 5625 C C   . GLU E 5 45  ? 369.567 363.895 455.777 1.00 58.34  ? 45  GLU C C   1 
ATOM 5626 O O   . GLU E 5 45  ? 368.375 364.071 456.040 1.00 58.34  ? 45  GLU C O   1 
ATOM 5627 C CB  . GLU E 5 45  ? 369.484 362.756 453.543 1.00 58.34  ? 45  GLU C CB  1 
ATOM 5628 C CG  . GLU E 5 45  ? 369.812 361.413 454.127 1.00 58.34  ? 45  GLU C CG  1 
ATOM 5629 C CD  . GLU E 5 45  ? 369.459 360.300 453.177 1.00 58.34  ? 45  GLU C CD  1 
ATOM 5630 O OE1 . GLU E 5 45  ? 369.120 360.604 452.015 1.00 58.34  ? 45  GLU C OE1 1 
ATOM 5631 O OE2 . GLU E 5 45  ? 369.494 359.126 453.591 1.00 58.34  ? 45  GLU C OE2 1 
ATOM 5632 N N   . ILE E 5 46  ? 370.475 363.627 456.713 1.00 55.44  ? 46  ILE C N   1 
ATOM 5633 C CA  . ILE E 5 46  ? 370.192 363.874 458.120 1.00 55.44  ? 46  ILE C CA  1 
ATOM 5634 C C   . ILE E 5 46  ? 370.302 365.362 458.418 1.00 55.44  ? 46  ILE C C   1 
ATOM 5635 O O   . ILE E 5 46  ? 369.573 365.891 459.261 1.00 55.44  ? 46  ILE C O   1 
ATOM 5636 C CB  . ILE E 5 46  ? 371.145 363.039 458.990 1.00 55.44  ? 46  ILE C CB  1 
ATOM 5637 C CG1 . ILE E 5 46  ? 371.027 361.563 458.626 1.00 55.44  ? 46  ILE C CG1 1 
ATOM 5638 C CG2 . ILE E 5 46  ? 370.876 363.230 460.466 1.00 55.44  ? 46  ILE C CG2 1 
ATOM 5639 C CD1 . ILE E 5 46  ? 371.875 360.654 459.487 1.00 55.44  ? 46  ILE C CD1 1 
ATOM 5640 N N   . ALA E 5 47  ? 371.173 366.070 457.707 1.00 57.30  ? 47  ALA C N   1 
ATOM 5641 C CA  . ALA E 5 47  ? 371.332 367.499 457.916 1.00 57.30  ? 47  ALA C CA  1 
ATOM 5642 C C   . ALA E 5 47  ? 370.187 368.310 457.337 1.00 57.30  ? 47  ALA C C   1 
ATOM 5643 O O   . ALA E 5 47  ? 369.889 369.388 457.854 1.00 57.30  ? 47  ALA C O   1 
ATOM 5644 C CB  . ALA E 5 47  ? 372.646 367.974 457.304 1.00 57.30  ? 47  ALA C CB  1 
ATOM 5645 N N   . GLU E 5 48  ? 369.529 367.815 456.297 1.00 60.23  ? 48  GLU C N   1 
ATOM 5646 C CA  . GLU E 5 48  ? 368.519 368.592 455.593 1.00 60.23  ? 48  GLU C CA  1 
ATOM 5647 C C   . GLU E 5 48  ? 367.129 368.475 456.198 1.00 60.23  ? 48  GLU C C   1 
ATOM 5648 O O   . GLU E 5 48  ? 366.147 368.671 455.479 1.00 60.23  ? 48  GLU C O   1 
ATOM 5649 C CB  . GLU E 5 48  ? 368.487 368.186 454.121 1.00 60.23  ? 48  GLU C CB  1 
ATOM 5650 C CG  . GLU E 5 48  ? 369.447 369.003 453.268 1.00 60.23  ? 48  GLU C CG  1 
ATOM 5651 C CD  . GLU E 5 48  ? 370.123 368.197 452.173 1.00 60.23  ? 48  GLU C CD  1 
ATOM 5652 O OE1 . GLU E 5 48  ? 371.071 368.721 451.552 1.00 60.23  ? 48  GLU C OE1 1 
ATOM 5653 O OE2 . GLU E 5 48  ? 369.711 367.044 451.930 1.00 60.23  ? 48  GLU C OE2 1 
ATOM 5654 N N   . VAL E 5 49  ? 367.017 368.154 457.481 1.00 55.55  ? 49  VAL C N   1 
ATOM 5655 C CA  . VAL E 5 49  ? 365.750 368.215 458.198 1.00 55.55  ? 49  VAL C CA  1 
ATOM 5656 C C   . VAL E 5 49  ? 365.847 369.305 459.255 1.00 55.55  ? 49  VAL C C   1 
ATOM 5657 O O   . VAL E 5 49  ? 366.941 369.702 459.663 1.00 55.55  ? 49  VAL C O   1 
ATOM 5658 C CB  . VAL E 5 49  ? 365.385 366.848 458.810 1.00 55.55  ? 49  VAL C CB  1 
ATOM 5659 C CG1 . VAL E 5 49  ? 365.408 365.774 457.749 1.00 55.55  ? 49  VAL C CG1 1 
ATOM 5660 C CG2 . VAL E 5 49  ? 366.338 366.488 459.897 1.00 55.55  ? 49  VAL C CG2 1 
ATOM 5661 N N   . ASP E 5 50  ? 364.698 369.810 459.689 1.00 55.63  ? 50  ASP C N   1 
ATOM 5662 C CA  . ASP E 5 50  ? 364.651 370.969 460.565 1.00 55.63  ? 50  ASP C CA  1 
ATOM 5663 C C   . ASP E 5 50  ? 365.026 370.590 461.992 1.00 55.63  ? 50  ASP C C   1 
ATOM 5664 O O   . ASP E 5 50  ? 365.003 369.419 462.373 1.00 55.63  ? 50  ASP C O   1 
ATOM 5665 C CB  . ASP E 5 50  ? 363.259 371.590 460.546 1.00 55.63  ? 50  ASP C CB  1 
ATOM 5666 C CG  . ASP E 5 50  ? 363.009 372.424 459.306 1.00 55.63  ? 50  ASP C CG  1 
ATOM 5667 O OD1 . ASP E 5 50  ? 363.992 372.884 458.700 1.00 55.63  ? 50  ASP C OD1 1 
ATOM 5668 O OD2 . ASP E 5 50  ? 361.833 372.625 458.933 1.00 55.63  ? 50  ASP C OD2 1 
ATOM 5669 N N   . SER E 5 51  ? 365.364 371.605 462.787 1.00 49.48  ? 51  SER C N   1 
ATOM 5670 C CA  . SER E 5 51  ? 365.724 371.424 464.188 1.00 49.48  ? 51  SER C CA  1 
ATOM 5671 C C   . SER E 5 51  ? 365.623 372.763 464.896 1.00 49.48  ? 51  SER C C   1 
ATOM 5672 O O   . SER E 5 51  ? 366.004 373.794 464.344 1.00 49.48  ? 51  SER C O   1 
ATOM 5673 C CB  . SER E 5 51  ? 367.135 370.866 464.337 1.00 49.48  ? 51  SER C CB  1 
ATOM 5674 O OG  . SER E 5 51  ? 368.003 371.483 463.410 1.00 49.48  ? 51  SER C OG  1 
ATOM 5675 N N   . VAL E 5 52  ? 365.136 372.736 466.124 1.00 44.68  ? 52  VAL C N   1 
ATOM 5676 C CA  . VAL E 5 52  ? 364.858 373.961 466.862 1.00 44.68  ? 52  VAL C CA  1 
ATOM 5677 C C   . VAL E 5 52  ? 366.156 374.503 467.447 1.00 44.68  ? 52  VAL C C   1 
ATOM 5678 O O   . VAL E 5 52  ? 366.970 373.749 467.986 1.00 44.68  ? 52  VAL C O   1 
ATOM 5679 C CB  . VAL E 5 52  ? 363.809 373.684 467.951 1.00 44.68  ? 52  VAL C CB  1 
ATOM 5680 C CG1 . VAL E 5 52  ? 363.392 374.950 468.636 1.00 44.68  ? 52  VAL C CG1 1 
ATOM 5681 C CG2 . VAL E 5 52  ? 362.617 373.006 467.350 1.00 44.68  ? 52  VAL C CG2 1 
ATOM 5682 N N   . VAL E 5 53  ? 366.350 375.811 467.349 1.00 45.47  ? 53  VAL C N   1 
ATOM 5683 C CA  . VAL E 5 53  ? 367.609 376.467 467.703 1.00 45.47  ? 53  VAL C CA  1 
ATOM 5684 C C   . VAL E 5 53  ? 367.461 377.106 469.078 1.00 45.47  ? 53  VAL C C   1 
ATOM 5685 O O   . VAL E 5 53  ? 366.474 377.813 469.308 1.00 45.47  ? 53  VAL C O   1 
ATOM 5686 C CB  . VAL E 5 53  ? 367.988 377.529 466.658 1.00 45.47  ? 53  VAL C CB  1 
ATOM 5687 C CG1 . VAL E 5 53  ? 369.265 378.230 467.029 1.00 45.47  ? 53  VAL C CG1 1 
ATOM 5688 C CG2 . VAL E 5 53  ? 368.119 376.895 465.322 1.00 45.47  ? 53  VAL C CG2 1 
ATOM 5689 N N   . PRO E 5 54  ? 368.398 376.898 469.999 1.00 45.85  ? 54  PRO C N   1 
ATOM 5690 C CA  . PRO E 5 54  ? 368.329 377.571 471.308 1.00 45.85  ? 54  PRO C CA  1 
ATOM 5691 C C   . PRO E 5 54  ? 368.881 378.993 471.282 1.00 45.85  ? 54  PRO C C   1 
ATOM 5692 O O   . PRO E 5 54  ? 370.004 379.282 471.674 1.00 45.85  ? 54  PRO C O   1 
ATOM 5693 C CB  . PRO E 5 54  ? 369.165 376.651 472.197 1.00 45.85  ? 54  PRO C CB  1 
ATOM 5694 C CG  . PRO E 5 54  ? 370.139 376.042 471.287 1.00 45.85  ? 54  PRO C CG  1 
ATOM 5695 C CD  . PRO E 5 54  ? 369.507 375.936 469.938 1.00 45.85  ? 54  PRO C CD  1 
ATOM 5696 N N   . VAL E 5 55  ? 368.051 379.933 470.826 1.00 46.94  ? 55  VAL C N   1 
ATOM 5697 C CA  . VAL E 5 55  ? 368.501 381.312 470.652 1.00 46.94  ? 55  VAL C CA  1 
ATOM 5698 C C   . VAL E 5 55  ? 368.508 382.080 471.963 1.00 46.94  ? 55  VAL C C   1 
ATOM 5699 O O   . VAL E 5 55  ? 369.116 383.151 472.048 1.00 46.94  ? 55  VAL C O   1 
ATOM 5700 C CB  . VAL E 5 55  ? 367.608 381.990 469.594 1.00 46.94  ? 55  VAL C CB  1 
ATOM 5701 C CG1 . VAL E 5 55  ? 368.278 383.210 468.978 1.00 46.94  ? 55  VAL C CG1 1 
ATOM 5702 C CG2 . VAL E 5 55  ? 367.249 381.016 468.511 1.00 46.94  ? 55  VAL C CG2 1 
ATOM 5703 N N   . ASN E 5 56  ? 367.928 381.526 473.018 1.00 50.77  ? 56  ASN C N   1 
ATOM 5704 C CA  . ASN E 5 56  ? 367.721 382.258 474.259 1.00 50.77  ? 56  ASN C CA  1 
ATOM 5705 C C   . ASN E 5 56  ? 368.497 381.609 475.395 1.00 50.77  ? 56  ASN C C   1 
ATOM 5706 O O   . ASN E 5 56  ? 367.898 381.200 476.394 1.00 50.77  ? 56  ASN C O   1 
ATOM 5707 C CB  . ASN E 5 56  ? 366.236 382.338 474.599 1.00 50.77  ? 56  ASN C CB  1 
ATOM 5708 C CG  . ASN E 5 56  ? 365.936 383.380 475.654 1.00 50.77  ? 56  ASN C CG  1 
ATOM 5709 O OD1 . ASN E 5 56  ? 366.747 384.263 475.911 1.00 50.77  ? 56  ASN C OD1 1 
ATOM 5710 N ND2 . ASN E 5 56  ? 364.780 383.266 476.289 1.00 50.77  ? 56  ASN C ND2 1 
ATOM 5711 N N   . ASN E 5 57  ? 369.808 381.423 475.206 1.00 53.10  ? 57  ASN C N   1 
ATOM 5712 C CA  . ASN E 5 57  ? 370.659 380.718 476.161 1.00 53.10  ? 57  ASN C CA  1 
ATOM 5713 C C   . ASN E 5 57  ? 370.644 381.372 477.538 1.00 53.10  ? 57  ASN C C   1 
ATOM 5714 O O   . ASN E 5 57  ? 370.099 380.794 478.480 1.00 53.10  ? 57  ASN C O   1 
ATOM 5715 C CB  . ASN E 5 57  ? 372.091 380.653 475.639 1.00 53.10  ? 57  ASN C CB  1 
ATOM 5716 C CG  . ASN E 5 57  ? 372.197 379.946 474.307 1.00 53.10  ? 57  ASN C CG  1 
ATOM 5717 O OD1 . ASN E 5 57  ? 373.146 380.154 473.558 1.00 53.10  ? 57  ASN C OD1 1 
ATOM 5718 N ND2 . ASN E 5 57  ? 371.230 379.098 474.009 1.00 53.10  ? 57  ASN C ND2 1 
ATOM 5719 N N   . THR E 5 58  ? 371.231 382.568 477.651 1.00 59.42  ? 58  THR C N   1 
ATOM 5720 C CA  . THR E 5 58  ? 370.961 383.553 478.712 1.00 59.42  ? 58  THR C CA  1 
ATOM 5721 C C   . THR E 5 58  ? 371.275 383.004 480.118 1.00 59.42  ? 58  THR C C   1 
ATOM 5722 O O   . THR E 5 58  ? 370.667 383.397 481.116 1.00 59.42  ? 58  THR C O   1 
ATOM 5723 C CB  . THR E 5 58  ? 369.512 384.056 478.591 1.00 59.42  ? 58  THR C CB  1 
ATOM 5724 O OG1 . THR E 5 58  ? 369.226 384.259 477.206 1.00 59.42  ? 58  THR C OG1 1 
ATOM 5725 C CG2 . THR E 5 58  ? 369.323 385.453 479.201 1.00 59.42  ? 58  THR C CG2 1 
ATOM 5726 N N   . GLU E 5 59  ? 372.163 382.007 480.197 1.00 63.14  ? 59  GLU C N   1 
ATOM 5727 C CA  . GLU E 5 59  ? 372.882 381.581 481.405 1.00 63.14  ? 59  GLU C CA  1 
ATOM 5728 C C   . GLU E 5 59  ? 372.001 380.897 482.466 1.00 63.14  ? 59  GLU C C   1 
ATOM 5729 O O   . GLU E 5 59  ? 372.510 380.259 483.392 1.00 63.14  ? 59  GLU C O   1 
ATOM 5730 C CB  . GLU E 5 59  ? 373.639 382.808 481.967 1.00 63.14  ? 59  GLU C CB  1 
ATOM 5731 C CG  . GLU E 5 59  ? 374.503 382.660 483.204 1.00 63.14  ? 59  GLU C CG  1 
ATOM 5732 C CD  . GLU E 5 59  ? 375.399 381.456 483.131 1.00 63.14  ? 59  GLU C CD  1 
ATOM 5733 O OE1 . GLU E 5 59  ? 376.228 381.391 482.205 1.00 63.14  ? 59  GLU C OE1 1 
ATOM 5734 O OE2 . GLU E 5 59  ? 375.265 380.569 483.992 1.00 63.14  ? 59  GLU C OE2 1 
ATOM 5735 N N   . ASP E 5 60  ? 370.687 380.910 482.307 1.00 59.20  ? 60  ASP C N   1 
ATOM 5736 C CA  . ASP E 5 60  ? 369.839 380.170 483.229 1.00 59.20  ? 60  ASP C CA  1 
ATOM 5737 C C   . ASP E 5 60  ? 368.717 379.421 482.534 1.00 59.20  ? 60  ASP C C   1 
ATOM 5738 O O   . ASP E 5 60  ? 367.946 378.735 483.210 1.00 59.20  ? 60  ASP C O   1 
ATOM 5739 C CB  . ASP E 5 60  ? 369.258 381.104 484.301 1.00 59.20  ? 60  ASP C CB  1 
ATOM 5740 C CG  . ASP E 5 60  ? 368.742 382.407 483.734 1.00 59.20  ? 60  ASP C CG  1 
ATOM 5741 O OD1 . ASP E 5 60  ? 368.387 382.462 482.542 1.00 59.20  ? 60  ASP C OD1 1 
ATOM 5742 O OD2 . ASP E 5 60  ? 368.695 383.395 484.493 1.00 59.20  ? 60  ASP C OD2 1 
ATOM 5743 N N   . ASN E 5 61  ? 368.601 379.530 481.217 1.00 55.44  ? 61  ASN C N   1 
ATOM 5744 C CA  . ASN E 5 61  ? 367.586 378.832 480.455 1.00 55.44  ? 61  ASN C CA  1 
ATOM 5745 C C   . ASN E 5 61  ? 368.109 377.563 479.812 1.00 55.44  ? 61  ASN C C   1 
ATOM 5746 O O   . ASN E 5 61  ? 367.330 376.846 479.184 1.00 55.44  ? 61  ASN C O   1 
ATOM 5747 C CB  . ASN E 5 61  ? 367.021 379.745 479.372 1.00 55.44  ? 61  ASN C CB  1 
ATOM 5748 C CG  . ASN E 5 61  ? 366.569 381.067 479.912 1.00 55.44  ? 61  ASN C CG  1 
ATOM 5749 O OD1 . ASN E 5 61  ? 366.144 381.169 481.057 1.00 55.44  ? 61  ASN C OD1 1 
ATOM 5750 N ND2 . ASN E 5 61  ? 366.651 382.096 479.088 1.00 55.44  ? 61  ASN C ND2 1 
ATOM 5751 N N   . VAL E 5 62  ? 369.400 377.266 479.956 1.00 54.39  ? 62  VAL C N   1 
ATOM 5752 C CA  . VAL E 5 62  ? 369.981 376.136 479.242 1.00 54.39  ? 62  VAL C CA  1 
ATOM 5753 C C   . VAL E 5 62  ? 369.516 374.813 479.828 1.00 54.39  ? 62  VAL C C   1 
ATOM 5754 O O   . VAL E 5 62  ? 369.433 373.809 479.115 1.00 54.39  ? 62  VAL C O   1 
ATOM 5755 C CB  . VAL E 5 62  ? 371.511 376.247 479.238 1.00 54.39  ? 62  VAL C CB  1 
ATOM 5756 C CG1 . VAL E 5 62  ? 371.943 377.265 478.225 1.00 54.39  ? 62  VAL C CG1 1 
ATOM 5757 C CG2 . VAL E 5 62  ? 372.003 376.646 480.608 1.00 54.39  ? 62  VAL C CG2 1 
ATOM 5758 N N   . SER E 5 63  ? 369.212 374.775 481.116 1.00 54.51  ? 63  SER C N   1 
ATOM 5759 C CA  . SER E 5 63  ? 368.601 373.593 481.717 1.00 54.51  ? 63  SER C CA  1 
ATOM 5760 C C   . SER E 5 63  ? 367.090 373.725 481.773 1.00 54.51  ? 63  SER C C   1 
ATOM 5761 O O   . SER E 5 63  ? 366.484 373.510 482.820 1.00 54.51  ? 63  SER C O   1 
ATOM 5762 C CB  . SER E 5 63  ? 369.166 373.363 483.105 1.00 54.51  ? 63  SER C CB  1 
ATOM 5763 O OG  . SER E 5 63  ? 368.398 374.066 484.061 1.00 54.51  ? 63  SER C OG  1 
ATOM 5764 N N   . SER E 5 64  ? 366.465 374.055 480.647 1.00 50.65  ? 64  SER C N   1 
ATOM 5765 C CA  . SER E 5 64  ? 365.022 374.248 480.578 1.00 50.65  ? 64  SER C CA  1 
ATOM 5766 C C   . SER E 5 64  ? 364.596 374.201 479.121 1.00 50.65  ? 64  SER C C   1 
ATOM 5767 O O   . SER E 5 64  ? 365.425 374.169 478.211 1.00 50.65  ? 64  SER C O   1 
ATOM 5768 C CB  . SER E 5 64  ? 364.600 375.573 481.209 1.00 50.65  ? 64  SER C CB  1 
ATOM 5769 O OG  . SER E 5 64  ? 363.207 375.761 481.067 1.00 50.65  ? 64  SER C OG  1 
ATOM 5770 N N   . LEU E 5 65  ? 363.286 374.208 478.904 1.00 46.50  ? 65  LEU C N   1 
ATOM 5771 C CA  . LEU E 5 65  ? 362.724 374.385 477.575 1.00 46.50  ? 65  LEU C CA  1 
ATOM 5772 C C   . LEU E 5 65  ? 362.568 375.850 477.213 1.00 46.50  ? 65  LEU C C   1 
ATOM 5773 O O   . LEU E 5 65  ? 362.078 376.160 476.126 1.00 46.50  ? 65  LEU C O   1 
ATOM 5774 C CB  . LEU E 5 65  ? 361.375 373.682 477.469 1.00 46.50  ? 65  LEU C CB  1 
ATOM 5775 C CG  . LEU E 5 65  ? 361.383 372.279 476.876 1.00 46.50  ? 65  LEU C CG  1 
ATOM 5776 C CD1 . LEU E 5 65  ? 360.024 371.644 477.015 1.00 46.50  ? 65  LEU C CD1 1 
ATOM 5777 C CD2 . LEU E 5 65  ? 361.781 372.344 475.430 1.00 46.50  ? 65  LEU C CD2 1 
ATOM 5778 N N   . LYS E 5 66  ? 362.968 376.754 478.104 1.00 48.58  ? 66  LYS C N   1 
ATOM 5779 C CA  . LYS E 5 66  ? 362.935 378.182 477.836 1.00 48.58  ? 66  LYS C CA  1 
ATOM 5780 C C   . LYS E 5 66  ? 364.102 378.646 476.990 1.00 48.58  ? 66  LYS C C   1 
ATOM 5781 O O   . LYS E 5 66  ? 364.145 379.824 476.629 1.00 48.58  ? 66  LYS C O   1 
ATOM 5782 C CB  . LYS E 5 66  ? 362.936 378.968 479.143 1.00 48.58  ? 66  LYS C CB  1 
ATOM 5783 C CG  . LYS E 5 66  ? 361.653 378.876 479.931 1.00 48.58  ? 66  LYS C CG  1 
ATOM 5784 C CD  . LYS E 5 66  ? 361.662 379.867 481.069 1.00 48.58  ? 66  LYS C CD  1 
ATOM 5785 C CE  . LYS E 5 66  ? 361.032 381.178 480.639 1.00 48.58  ? 66  LYS C CE  1 
ATOM 5786 N NZ  . LYS E 5 66  ? 361.478 382.322 481.482 1.00 48.58  ? 66  LYS C NZ  1 
ATOM 5787 N N   . ALA E 5 67  ? 365.054 377.765 476.684 1.00 47.13  ? 67  ALA C N   1 
ATOM 5788 C CA  . ALA E 5 67  ? 366.185 378.161 475.857 1.00 47.13  ? 67  ALA C CA  1 
ATOM 5789 C C   . ALA E 5 67  ? 365.774 378.365 474.415 1.00 47.13  ? 67  ALA C C   1 
ATOM 5790 O O   . ALA E 5 67  ? 366.452 379.084 473.678 1.00 47.13  ? 67  ALA C O   1 
ATOM 5791 C CB  . ALA E 5 67  ? 367.292 377.118 475.930 1.00 47.13  ? 67  ALA C CB  1 
ATOM 5792 N N   . TYR E 5 68  ? 364.678 377.753 473.998 1.00 45.55  ? 68  TYR C N   1 
ATOM 5793 C CA  . TYR E 5 68  ? 364.248 377.822 472.615 1.00 45.55  ? 68  TYR C CA  1 
ATOM 5794 C C   . TYR E 5 68  ? 363.292 378.970 472.333 1.00 45.55  ? 68  TYR C C   1 
ATOM 5795 O O   . TYR E 5 68  ? 363.147 379.357 471.172 1.00 45.55  ? 68  TYR C O   1 
ATOM 5796 C CB  . TYR E 5 68  ? 363.583 376.508 472.220 1.00 45.55  ? 68  TYR C CB  1 
ATOM 5797 C CG  . TYR E 5 68  ? 364.457 375.299 472.403 1.00 45.55  ? 68  TYR C CG  1 
ATOM 5798 C CD1 . TYR E 5 68  ? 365.524 375.062 471.562 1.00 45.55  ? 68  TYR C CD1 1 
ATOM 5799 C CD2 . TYR E 5 68  ? 364.200 374.385 473.403 1.00 45.55  ? 68  TYR C CD2 1 
ATOM 5800 C CE1 . TYR E 5 68  ? 366.312 373.958 471.717 1.00 45.55  ? 68  TYR C CE1 1 
ATOM 5801 C CE2 . TYR E 5 68  ? 364.987 373.276 473.567 1.00 45.55  ? 68  TYR C CE2 1 
ATOM 5802 C CZ  . TYR E 5 68  ? 366.037 373.070 472.721 1.00 45.55  ? 68  TYR C CZ  1 
ATOM 5803 O OH  . TYR E 5 68  ? 366.828 371.967 472.879 1.00 45.55  ? 68  TYR C OH  1 
ATOM 5804 N N   . GLN E 5 69  ? 362.650 379.529 473.349 1.00 46.71  ? 69  GLN C N   1 
ATOM 5805 C CA  . GLN E 5 69  ? 361.581 380.498 473.163 1.00 46.71  ? 69  GLN C CA  1 
ATOM 5806 C C   . GLN E 5 69  ? 362.146 381.909 473.172 1.00 46.71  ? 69  GLN C C   1 
ATOM 5807 O O   . GLN E 5 69  ? 362.782 382.320 474.146 1.00 46.71  ? 69  GLN C O   1 
ATOM 5808 C CB  . GLN E 5 69  ? 360.532 380.348 474.257 1.00 46.71  ? 69  GLN C CB  1 
ATOM 5809 C CG  . GLN E 5 69  ? 360.105 378.925 474.494 1.00 46.71  ? 69  GLN C CG  1 
ATOM 5810 C CD  . GLN E 5 69  ? 359.328 378.770 475.772 1.00 46.71  ? 69  GLN C CD  1 
ATOM 5811 O OE1 . GLN E 5 69  ? 359.104 379.737 476.494 1.00 46.71  ? 69  GLN C OE1 1 
ATOM 5812 N NE2 . GLN E 5 69  ? 358.912 377.550 476.064 1.00 46.71  ? 69  GLN C NE2 1 
ATOM 5813 N N   . ILE E 5 70  ? 361.890 382.650 472.102 1.00 49.64  ? 70  ILE C N   1 
ATOM 5814 C CA  . ILE E 5 70  ? 362.291 384.048 471.983 1.00 49.64  ? 70  ILE C CA  1 
ATOM 5815 C C   . ILE E 5 70  ? 361.131 384.911 472.466 1.00 49.64  ? 70  ILE C C   1 
ATOM 5816 O O   . ILE E 5 70  ? 360.078 384.924 471.815 1.00 49.64  ? 70  ILE C O   1 
ATOM 5817 C CB  . ILE E 5 70  ? 362.666 384.396 470.539 1.00 49.64  ? 70  ILE C CB  1 
ATOM 5818 C CG1 . ILE E 5 70  ? 363.696 383.406 470.016 1.00 49.64  ? 70  ILE C CG1 1 
ATOM 5819 C CG2 . ILE E 5 70  ? 363.206 385.792 470.468 1.00 49.64  ? 70  ILE C CG2 1 
ATOM 5820 C CD1 . ILE E 5 70  ? 364.069 383.626 468.584 1.00 49.64  ? 70  ILE C CD1 1 
ATOM 5821 N N   . PRO E 5 71  ? 361.273 385.635 473.571 1.00 51.20  ? 71  PRO C N   1 
ATOM 5822 C CA  . PRO E 5 71  ? 360.129 386.350 474.140 1.00 51.20  ? 71  PRO C CA  1 
ATOM 5823 C C   . PRO E 5 71  ? 359.770 387.591 473.343 1.00 51.20  ? 71  PRO C C   1 
ATOM 5824 O O   . PRO E 5 71  ? 360.635 388.294 472.817 1.00 51.20  ? 71  PRO C O   1 
ATOM 5825 C CB  . PRO E 5 71  ? 360.611 386.730 475.545 1.00 51.20  ? 71  PRO C CB  1 
ATOM 5826 C CG  . PRO E 5 71  ? 361.872 385.991 475.753 1.00 51.20  ? 71  PRO C CG  1 
ATOM 5827 C CD  . PRO E 5 71  ? 362.463 385.780 474.412 1.00 51.20  ? 71  PRO C CD  1 
ATOM 5828 N N   . VAL E 5 72  ? 358.470 387.860 473.269 1.00 57.65  ? 72  VAL C N   1 
ATOM 5829 C CA  . VAL E 5 72  ? 357.930 389.037 472.603 1.00 57.65  ? 72  VAL C CA  1 
ATOM 5830 C C   . VAL E 5 72  ? 356.930 389.681 473.550 1.00 57.65  ? 72  VAL C C   1 
ATOM 5831 O O   . VAL E 5 72  ? 356.011 389.011 474.031 1.00 57.65  ? 72  VAL C O   1 
ATOM 5832 C CB  . VAL E 5 72  ? 357.265 388.677 471.266 1.00 57.65  ? 72  VAL C CB  1 
ATOM 5833 C CG1 . VAL E 5 72  ? 356.322 389.767 470.814 1.00 57.65  ? 72  VAL C CG1 1 
ATOM 5834 C CG2 . VAL E 5 72  ? 358.312 388.438 470.219 1.00 57.65  ? 72  VAL C CG2 1 
ATOM 5835 N N   . GLN E 5 73  ? 357.120 390.963 473.841 1.00 64.03  ? 73  GLN C N   1 
ATOM 5836 C CA  . GLN E 5 73  ? 356.147 391.739 474.589 1.00 64.03  ? 73  GLN C CA  1 
ATOM 5837 C C   . GLN E 5 73  ? 355.937 393.073 473.895 1.00 64.03  ? 73  GLN C C   1 
ATOM 5838 O O   . GLN E 5 73  ? 356.812 393.578 473.191 1.00 64.03  ? 73  GLN C O   1 
ATOM 5839 C CB  . GLN E 5 73  ? 356.581 391.950 476.042 1.00 64.03  ? 73  GLN C CB  1 
ATOM 5840 C CG  . GLN E 5 73  ? 357.861 392.737 476.216 1.00 64.03  ? 73  GLN C CG  1 
ATOM 5841 C CD  . GLN E 5 73  ? 359.074 391.841 476.341 1.00 64.03  ? 73  GLN C CD  1 
ATOM 5842 O OE1 . GLN E 5 73  ? 359.038 390.673 475.962 1.00 64.03  ? 73  GLN C OE1 1 
ATOM 5843 N NE2 . GLN E 5 73  ? 360.153 392.380 476.887 1.00 64.03  ? 73  GLN C NE2 1 
ATOM 5844 N N   . SER E 5 74  ? 354.755 393.644 474.096 1.00 70.83  ? 74  SER C N   1 
ATOM 5845 C CA  . SER E 5 74  ? 354.383 394.905 473.461 1.00 70.83  ? 74  SER C CA  1 
ATOM 5846 C C   . SER E 5 74  ? 354.998 396.040 474.267 1.00 70.83  ? 74  SER C C   1 
ATOM 5847 O O   . SER E 5 74  ? 354.450 396.465 475.287 1.00 70.83  ? 74  SER C O   1 
ATOM 5848 C CB  . SER E 5 74  ? 352.869 395.036 473.374 1.00 70.83  ? 74  SER C CB  1 
ATOM 5849 O OG  . SER E 5 74  ? 352.340 395.536 474.586 1.00 70.83  ? 74  SER C OG  1 
ATOM 5850 N N   . ASN E 5 75  ? 356.131 396.544 473.802 1.00 76.69  ? 75  ASN C N   1 
ATOM 5851 C CA  . ASN E 5 75  ? 356.893 397.550 474.516 1.00 76.69  ? 75  ASN C CA  1 
ATOM 5852 C C   . ASN E 5 75  ? 356.296 398.936 474.276 1.00 76.69  ? 75  ASN C C   1 
ATOM 5853 O O   . ASN E 5 75  ? 355.189 399.085 473.752 1.00 76.69  ? 75  ASN C O   1 
ATOM 5854 C CB  . ASN E 5 75  ? 358.363 397.481 474.098 1.00 76.69  ? 75  ASN C CB  1 
ATOM 5855 C CG  . ASN E 5 75  ? 358.597 398.007 472.699 1.00 76.69  ? 75  ASN C CG  1 
ATOM 5856 O OD1 . ASN E 5 75  ? 357.773 397.822 471.809 1.00 76.69  ? 75  ASN C OD1 1 
ATOM 5857 N ND2 . ASN E 5 75  ? 359.722 398.672 472.500 1.00 76.69  ? 75  ASN C ND2 1 
ATOM 5858 N N   . SER E 5 76  ? 357.040 399.968 474.664 1.00 85.95  ? 76  SER C N   1 
ATOM 5859 C CA  . SER E 5 76  ? 356.631 401.349 474.467 1.00 85.95  ? 76  SER C CA  1 
ATOM 5860 C C   . SER E 5 76  ? 357.591 402.136 473.586 1.00 85.95  ? 76  SER C C   1 
ATOM 5861 O O   . SER E 5 76  ? 357.241 403.234 473.142 1.00 85.95  ? 76  SER C O   1 
ATOM 5862 C CB  . SER E 5 76  ? 356.480 402.039 475.827 1.00 85.95  ? 76  SER C CB  1 
ATOM 5863 O OG  . SER E 5 76  ? 357.528 401.657 476.700 1.00 85.95  ? 76  SER C OG  1 
ATOM 5864 N N   . ASP E 5 77  ? 358.779 401.608 473.311 1.00 89.02  ? 77  ASP C N   1 
ATOM 5865 C CA  . ASP E 5 77  ? 359.770 402.309 472.510 1.00 89.02  ? 77  ASP C CA  1 
ATOM 5866 C C   . ASP E 5 77  ? 359.463 402.166 471.026 1.00 89.02  ? 77  ASP C C   1 
ATOM 5867 O O   . ASP E 5 77  ? 358.812 401.213 470.591 1.00 89.02  ? 77  ASP C O   1 
ATOM 5868 C CB  . ASP E 5 77  ? 361.175 401.778 472.794 1.00 89.02  ? 77  ASP C CB  1 
ATOM 5869 C CG  . ASP E 5 77  ? 361.541 401.859 474.259 1.00 89.02  ? 77  ASP C CG  1 
ATOM 5870 O OD1 . ASP E 5 77  ? 360.720 402.371 475.046 1.00 89.02  ? 77  ASP C OD1 1 
ATOM 5871 O OD2 . ASP E 5 77  ? 362.649 401.409 474.623 1.00 89.02  ? 77  ASP C OD2 1 
ATOM 5872 N N   . ASN E 5 78  ? 359.948 403.128 470.248 1.00 90.63  ? 78  ASN C N   1 
ATOM 5873 C CA  . ASN E 5 78  ? 359.757 403.142 468.800 1.00 90.63  ? 78  ASN C CA  1 
ATOM 5874 C C   . ASN E 5 78  ? 360.977 402.478 468.172 1.00 90.63  ? 78  ASN C C   1 
ATOM 5875 O O   . ASN E 5 78  ? 362.013 403.107 467.964 1.00 90.63  ? 78  ASN C O   1 
ATOM 5876 C CB  . ASN E 5 78  ? 359.555 404.565 468.293 1.00 90.63  ? 78  ASN C CB  1 
ATOM 5877 C CG  . ASN E 5 78  ? 358.608 404.634 467.113 1.00 90.63  ? 78  ASN C CG  1 
ATOM 5878 O OD1 . ASN E 5 78  ? 357.867 403.689 466.841 1.00 90.63  ? 78  ASN C OD1 1 
ATOM 5879 N ND2 . ASN E 5 78  ? 358.627 405.757 466.404 1.00 90.63  ? 78  ASN C ND2 1 
ATOM 5880 N N   . GLY E 5 79  ? 360.856 401.185 467.889 1.00 77.48  ? 79  GLY C N   1 
ATOM 5881 C CA  . GLY E 5 79  ? 361.960 400.444 467.318 1.00 77.48  ? 79  GLY C CA  1 
ATOM 5882 C C   . GLY E 5 79  ? 362.875 399.924 468.402 1.00 77.48  ? 79  GLY C C   1 
ATOM 5883 O O   . GLY E 5 79  ? 363.412 400.707 469.191 1.00 77.48  ? 79  GLY C O   1 
ATOM 5884 N N   . LYS E 5 80  ? 363.058 398.609 468.454 1.00 63.17  ? 80  LYS C N   1 
ATOM 5885 C CA  . LYS E 5 80  ? 363.867 397.977 469.483 1.00 63.17  ? 80  LYS C CA  1 
ATOM 5886 C C   . LYS E 5 80  ? 364.216 396.581 469.003 1.00 63.17  ? 80  LYS C C   1 
ATOM 5887 O O   . LYS E 5 80  ? 363.473 395.991 468.218 1.00 63.17  ? 80  LYS C O   1 
ATOM 5888 C CB  . LYS E 5 80  ? 363.125 397.920 470.822 1.00 63.17  ? 80  LYS C CB  1 
ATOM 5889 C CG  . LYS E 5 80  ? 364.027 397.749 472.023 1.00 63.17  ? 80  LYS C CG  1 
ATOM 5890 C CD  . LYS E 5 80  ? 363.308 398.069 473.313 1.00 63.17  ? 80  LYS C CD  1 
ATOM 5891 C CE  . LYS E 5 80  ? 363.706 397.093 474.399 1.00 63.17  ? 80  LYS C CE  1 
ATOM 5892 N NZ  . LYS E 5 80  ? 365.105 396.617 474.226 1.00 63.17  ? 80  LYS C NZ  1 
ATOM 5893 N N   . GLN E 5 81  ? 365.346 396.062 469.463 1.00 57.26  ? 81  GLN C N   1 
ATOM 5894 C CA  . GLN E 5 81  ? 365.823 394.777 468.984 1.00 57.26  ? 81  GLN C CA  1 
ATOM 5895 C C   . GLN E 5 81  ? 365.156 393.638 469.739 1.00 57.26  ? 81  GLN C C   1 
ATOM 5896 O O   . GLN E 5 81  ? 364.961 393.717 470.955 1.00 57.26  ? 81  GLN C O   1 
ATOM 5897 C CB  . GLN E 5 81  ? 367.336 394.689 469.130 1.00 57.26  ? 81  GLN C CB  1 
ATOM 5898 C CG  . GLN E 5 81  ? 367.969 393.721 468.174 1.00 57.26  ? 81  GLN C CG  1 
ATOM 5899 C CD  . GLN E 5 81  ? 369.431 393.544 468.440 1.00 57.26  ? 81  GLN C CD  1 
ATOM 5900 O OE1 . GLN E 5 81  ? 369.940 393.983 469.465 1.00 57.26  ? 81  GLN C OE1 1 
ATOM 5901 N NE2 . GLN E 5 81  ? 370.121 392.894 467.524 1.00 57.26  ? 81  GLN C NE2 1 
ATOM 5902 N N   . VAL E 5 82  ? 364.808 392.578 469.015 1.00 53.14  ? 82  VAL C N   1 
ATOM 5903 C CA  . VAL E 5 82  ? 364.260 391.386 469.653 1.00 53.14  ? 82  VAL C CA  1 
ATOM 5904 C C   . VAL E 5 82  ? 365.373 390.408 470.003 1.00 53.14  ? 82  VAL C C   1 
ATOM 5905 O O   . VAL E 5 82  ? 365.587 390.080 471.173 1.00 53.14  ? 82  VAL C O   1 
ATOM 5906 C CB  . VAL E 5 82  ? 363.197 390.737 468.753 1.00 53.14  ? 82  VAL C CB  1 
ATOM 5907 C CG1 . VAL E 5 82  ? 362.743 389.429 469.341 1.00 53.14  ? 82  VAL C CG1 1 
ATOM 5908 C CG2 . VAL E 5 82  ? 362.028 391.660 468.598 1.00 53.14  ? 82  VAL C CG2 1 
ATOM 5909 N N   . PHE E 5 83  ? 366.103 389.936 468.999 1.00 50.82  ? 83  PHE C N   1 
ATOM 5910 C CA  . PHE E 5 83  ? 367.249 389.072 469.229 1.00 50.82  ? 83  PHE C CA  1 
ATOM 5911 C C   . PHE E 5 83  ? 368.338 389.444 468.237 1.00 50.82  ? 83  PHE C C   1 
ATOM 5912 O O   . PHE E 5 83  ? 368.212 390.400 467.470 1.00 50.82  ? 83  PHE C O   1 
ATOM 5913 C CB  . PHE E 5 83  ? 366.866 387.588 469.128 1.00 50.82  ? 83  PHE C CB  1 
ATOM 5914 C CG  . PHE E 5 83  ? 366.356 387.166 467.779 1.00 50.82  ? 83  PHE C CG  1 
ATOM 5915 C CD1 . PHE E 5 83  ? 365.008 387.220 467.498 1.00 50.82  ? 83  PHE C CD1 1 
ATOM 5916 C CD2 . PHE E 5 83  ? 367.213 386.669 466.814 1.00 50.82  ? 83  PHE C CD2 1 
ATOM 5917 C CE1 . PHE E 5 83  ? 364.531 386.823 466.280 1.00 50.82  ? 83  PHE C CE1 1 
ATOM 5918 C CE2 . PHE E 5 83  ? 366.739 386.282 465.594 1.00 50.82  ? 83  PHE C CE2 1 
ATOM 5919 C CZ  . PHE E 5 83  ? 365.397 386.363 465.329 1.00 50.82  ? 83  PHE C CZ  1 
ATOM 5920 N N   . GLY E 5 84  ? 369.415 388.675 468.259 1.00 51.12  ? 84  GLY C N   1 
ATOM 5921 C CA  . GLY E 5 84  ? 370.474 388.788 467.284 1.00 51.12  ? 84  GLY C CA  1 
ATOM 5922 C C   . GLY E 5 84  ? 371.590 387.833 467.633 1.00 51.12  ? 84  GLY C C   1 
ATOM 5923 O O   . GLY E 5 84  ? 372.011 387.776 468.790 1.00 51.12  ? 84  GLY C O   1 
ATOM 5924 N N   . PHE E 5 85  ? 372.077 387.072 466.657 1.00 49.89  ? 85  PHE C N   1 
ATOM 5925 C CA  . PHE E 5 85  ? 373.128 386.126 466.944 1.00 49.89  ? 85  PHE C CA  1 
ATOM 5926 C C   . PHE E 5 85  ? 374.072 386.095 465.756 1.00 49.89  ? 85  PHE C C   1 
ATOM 5927 O O   . PHE E 5 85  ? 373.611 386.196 464.614 1.00 49.89  ? 85  PHE C O   1 
ATOM 5928 C CB  . PHE E 5 85  ? 372.588 384.718 467.243 1.00 49.89  ? 85  PHE C CB  1 
ATOM 5929 C CG  . PHE E 5 85  ? 371.724 384.131 466.157 1.00 49.89  ? 85  PHE C CG  1 
ATOM 5930 C CD1 . PHE E 5 85  ? 370.359 384.337 466.159 1.00 49.89  ? 85  PHE C CD1 1 
ATOM 5931 C CD2 . PHE E 5 85  ? 372.269 383.324 465.171 1.00 49.89  ? 85  PHE C CD2 1 
ATOM 5932 C CE1 . PHE E 5 85  ? 369.567 383.792 465.179 1.00 49.89  ? 85  PHE C CE1 1 
ATOM 5933 C CE2 . PHE E 5 85  ? 371.480 382.781 464.190 1.00 49.89  ? 85  PHE C CE2 1 
ATOM 5934 C CZ  . PHE E 5 85  ? 370.131 383.014 464.195 1.00 49.89  ? 85  PHE C CZ  1 
ATOM 5935 N N   . PRO E 5 86  ? 375.374 385.968 465.979 1.00 52.89  ? 86  PRO C N   1 
ATOM 5936 C CA  . PRO E 5 86  ? 376.317 385.943 464.862 1.00 52.89  ? 86  PRO C CA  1 
ATOM 5937 C C   . PRO E 5 86  ? 376.321 384.590 464.171 1.00 52.89  ? 86  PRO C C   1 
ATOM 5938 O O   . PRO E 5 86  ? 375.634 383.651 464.568 1.00 52.89  ? 86  PRO C O   1 
ATOM 5939 C CB  . PRO E 5 86  ? 377.657 386.217 465.537 1.00 52.89  ? 86  PRO C CB  1 
ATOM 5940 C CG  . PRO E 5 86  ? 377.489 385.670 466.882 1.00 52.89  ? 86  PRO C CG  1 
ATOM 5941 C CD  . PRO E 5 86  ? 376.069 385.918 467.273 1.00 52.89  ? 86  PRO C CD  1 
ATOM 5942 N N   . LEU E 5 87  ? 377.122 384.503 463.114 1.00 55.46  ? 87  LEU C N   1 
ATOM 5943 C CA  . LEU E 5 87  ? 377.320 383.255 462.393 1.00 55.46  ? 87  LEU C CA  1 
ATOM 5944 C C   . LEU E 5 87  ? 378.774 382.801 462.439 1.00 55.46  ? 87  LEU C C   1 
ATOM 5945 O O   . LEU E 5 87  ? 379.229 382.081 461.553 1.00 55.46  ? 87  LEU C O   1 
ATOM 5946 C CB  . LEU E 5 87  ? 376.854 383.387 460.947 1.00 55.46  ? 87  LEU C CB  1 
ATOM 5947 C CG  . LEU E 5 87  ? 375.392 383.731 460.682 1.00 55.46  ? 87  LEU C CG  1 
ATOM 5948 C CD1 . LEU E 5 87  ? 375.246 384.183 459.259 1.00 55.46  ? 87  LEU C CD1 1 
ATOM 5949 C CD2 . LEU E 5 87  ? 374.500 382.544 460.935 1.00 55.46  ? 87  LEU C CD2 1 
ATOM 5950 N N   . GLN E 5 88  ? 379.510 383.223 463.453 1.00 61.84  ? 88  GLN C N   1 
ATOM 5951 C CA  . GLN E 5 88  ? 380.895 382.798 463.598 1.00 61.84  ? 88  GLN C CA  1 
ATOM 5952 C C   . GLN E 5 88  ? 380.937 381.355 464.078 1.00 61.84  ? 88  GLN C C   1 
ATOM 5953 O O   . GLN E 5 88  ? 380.463 381.063 465.180 1.00 61.84  ? 88  GLN C O   1 
ATOM 5954 C CB  . GLN E 5 88  ? 381.628 383.697 464.586 1.00 61.84  ? 88  GLN C CB  1 
ATOM 5955 C CG  . GLN E 5 88  ? 383.080 383.334 464.795 1.00 61.84  ? 88  GLN C CG  1 
ATOM 5956 C CD  . GLN E 5 88  ? 383.941 383.704 463.611 1.00 61.84  ? 88  GLN C CD  1 
ATOM 5957 O OE1 . GLN E 5 88  ? 383.635 384.644 462.880 1.00 61.84  ? 88  GLN C OE1 1 
ATOM 5958 N NE2 . GLN E 5 88  ? 385.023 382.964 463.410 1.00 61.84  ? 88  GLN C NE2 1 
ATOM 5959 N N   . PRO E 5 89  ? 381.495 380.431 463.296 1.00 61.21  ? 89  PRO C N   1 
ATOM 5960 C CA  . PRO E 5 89  ? 381.373 379.007 463.626 1.00 61.21  ? 89  PRO C CA  1 
ATOM 5961 C C   . PRO E 5 89  ? 382.321 378.610 464.747 1.00 61.21  ? 89  PRO C C   1 
ATOM 5962 O O   . PRO E 5 89  ? 383.375 379.220 464.933 1.00 61.21  ? 89  PRO C O   1 
ATOM 5963 C CB  . PRO E 5 89  ? 381.741 378.305 462.313 1.00 61.21  ? 89  PRO C CB  1 
ATOM 5964 C CG  . PRO E 5 89  ? 381.764 379.379 461.284 1.00 61.21  ? 89  PRO C CG  1 
ATOM 5965 C CD  . PRO E 5 89  ? 382.152 380.618 462.000 1.00 61.21  ? 89  PRO C CD  1 
ATOM 5966 N N   . GLY E 5 90  ? 381.925 377.593 465.510 1.00 62.38  ? 90  GLY C N   1 
ATOM 5967 C CA  . GLY E 5 90  ? 382.760 377.026 466.541 1.00 62.38  ? 90  GLY C CA  1 
ATOM 5968 C C   . GLY E 5 90  ? 382.795 377.781 467.849 1.00 62.38  ? 90  GLY C C   1 
ATOM 5969 O O   . GLY E 5 90  ? 382.688 377.154 468.910 1.00 62.38  ? 90  GLY C O   1 
ATOM 5970 N N   . ALA E 5 91  ? 382.916 379.109 467.821 1.00 66.56  ? 91  ALA C N   1 
ATOM 5971 C CA  . ALA E 5 91  ? 383.110 379.909 469.033 1.00 66.56  ? 91  ALA C CA  1 
ATOM 5972 C C   . ALA E 5 91  ? 381.790 380.037 469.792 1.00 66.56  ? 91  ALA C C   1 
ATOM 5973 O O   . ALA E 5 91  ? 381.201 381.117 469.897 1.00 66.56  ? 91  ALA C O   1 
ATOM 5974 C CB  . ALA E 5 91  ? 383.687 381.275 468.686 1.00 66.56  ? 91  ALA C CB  1 
ATOM 5975 N N   . ASN E 5 92  ? 381.362 378.899 470.364 1.00 63.79  ? 92  ASN C N   1 
ATOM 5976 C CA  . ASN E 5 92  ? 380.176 378.671 471.194 1.00 63.79  ? 92  ASN C CA  1 
ATOM 5977 C C   . ASN E 5 92  ? 378.915 379.401 470.739 1.00 63.79  ? 92  ASN C C   1 
ATOM 5978 O O   . ASN E 5 92  ? 378.181 379.955 471.562 1.00 63.79  ? 92  ASN C O   1 
ATOM 5979 C CB  . ASN E 5 92  ? 380.479 378.990 472.670 1.00 63.79  ? 92  ASN C CB  1 
ATOM 5980 C CG  . ASN E 5 92  ? 380.950 380.407 472.902 1.00 63.79  ? 92  ASN C CG  1 
ATOM 5981 O OD1 . ASN E 5 92  ? 382.147 380.674 472.937 1.00 63.79  ? 92  ASN C OD1 1 
ATOM 5982 N ND2 . ASN E 5 92  ? 380.010 381.323 473.067 1.00 63.79  ? 92  ASN C ND2 1 
ATOM 5983 N N   . ASN E 5 93  ? 378.646 379.393 469.440 1.00 57.80  ? 93  ASN C N   1 
ATOM 5984 C CA  . ASN E 5 93  ? 377.464 380.049 468.912 1.00 57.80  ? 93  ASN C CA  1 
ATOM 5985 C C   . ASN E 5 93  ? 376.262 379.119 469.047 1.00 57.80  ? 93  ASN C C   1 
ATOM 5986 O O   . ASN E 5 93  ? 376.387 377.959 469.440 1.00 57.80  ? 93  ASN C O   1 
ATOM 5987 C CB  . ASN E 5 93  ? 377.695 380.477 467.470 1.00 57.80  ? 93  ASN C CB  1 
ATOM 5988 C CG  . ASN E 5 93  ? 377.953 379.317 466.565 1.00 57.80  ? 93  ASN C CG  1 
ATOM 5989 O OD1 . ASN E 5 93  ? 378.496 378.302 466.986 1.00 57.80  ? 93  ASN C OD1 1 
ATOM 5990 N ND2 . ASN E 5 93  ? 377.567 379.452 465.308 1.00 57.80  ? 93  ASN C ND2 1 
ATOM 5991 N N   . VAL E 5 94  ? 375.078 379.623 468.710 1.00 50.83  ? 94  VAL C N   1 
ATOM 5992 C CA  . VAL E 5 94  ? 373.846 378.901 468.990 1.00 50.83  ? 94  VAL C CA  1 
ATOM 5993 C C   . VAL E 5 94  ? 373.564 377.769 468.015 1.00 50.83  ? 94  VAL C C   1 
ATOM 5994 O O   . VAL E 5 94  ? 372.774 376.874 468.336 1.00 50.83  ? 94  VAL C O   1 
ATOM 5995 C CB  . VAL E 5 94  ? 372.656 379.869 469.005 1.00 50.83  ? 94  VAL C CB  1 
ATOM 5996 C CG1 . VAL E 5 94  ? 372.736 380.749 470.213 1.00 50.83  ? 94  VAL C CG1 1 
ATOM 5997 C CG2 . VAL E 5 94  ? 372.671 380.710 467.768 1.00 50.83  ? 94  VAL C CG2 1 
ATOM 5998 N N   . LEU E 5 95  ? 374.188 377.768 466.844 1.00 49.38  ? 95  LEU C N   1 
ATOM 5999 C CA  . LEU E 5 95  ? 373.942 376.737 465.850 1.00 49.38  ? 95  LEU C CA  1 
ATOM 6000 C C   . LEU E 5 95  ? 374.828 375.519 466.039 1.00 49.38  ? 95  LEU C C   1 
ATOM 6001 O O   . LEU E 5 95  ? 375.003 374.740 465.100 1.00 49.38  ? 95  LEU C O   1 
ATOM 6002 C CB  . LEU E 5 95  ? 374.140 377.306 464.449 1.00 49.38  ? 95  LEU C CB  1 
ATOM 6003 C CG  . LEU E 5 95  ? 373.191 378.419 464.036 1.00 49.38  ? 95  LEU C CG  1 
ATOM 6004 C CD1 . LEU E 5 95  ? 373.706 379.093 462.803 1.00 49.38  ? 95  LEU C CD1 1 
ATOM 6005 C CD2 . LEU E 5 95  ? 371.837 377.850 463.770 1.00 49.38  ? 95  LEU C CD2 1 
ATOM 6006 N N   . ASN E 5 96  ? 375.379 375.326 467.230 1.00 53.30  ? 96  ASN C N   1 
ATOM 6007 C CA  . ASN E 5 96  ? 376.432 374.338 467.400 1.00 53.30  ? 96  ASN C CA  1 
ATOM 6008 C C   . ASN E 5 96  ? 375.870 372.972 467.760 1.00 53.30  ? 96  ASN C C   1 
ATOM 6009 O O   . ASN E 5 96  ? 376.312 371.953 467.225 1.00 53.30  ? 96  ASN C O   1 
ATOM 6010 C CB  . ASN E 5 96  ? 377.404 374.803 468.472 1.00 53.30  ? 96  ASN C CB  1 
ATOM 6011 C CG  . ASN E 5 96  ? 378.817 374.495 468.125 1.00 53.30  ? 96  ASN C CG  1 
ATOM 6012 O OD1 . ASN E 5 96  ? 379.107 374.041 467.026 1.00 53.30  ? 96  ASN C OD1 1 
ATOM 6013 N ND2 . ASN E 5 96  ? 379.718 374.733 469.060 1.00 53.30  ? 96  ASN C ND2 1 
ATOM 6014 N N   . ARG E 5 97  ? 374.908 372.925 468.670 1.00 51.43  ? 97  ARG C N   1 
ATOM 6015 C CA  . ARG E 5 97  ? 374.387 371.660 469.155 1.00 51.43  ? 97  ARG C CA  1 
ATOM 6016 C C   . ARG E 5 97  ? 373.209 371.154 468.344 1.00 51.43  ? 97  ARG C C   1 
ATOM 6017 O O   . ARG E 5 97  ? 372.590 370.166 468.741 1.00 51.43  ? 97  ARG C O   1 
ATOM 6018 C CB  . ARG E 5 97  ? 373.969 371.778 470.620 1.00 51.43  ? 97  ARG C CB  1 
ATOM 6019 C CG  . ARG E 5 97  ? 375.046 372.256 471.576 1.00 51.43  ? 97  ARG C CG  1 
ATOM 6020 C CD  . ARG E 5 97  ? 376.349 371.514 471.410 1.00 51.43  ? 97  ARG C CD  1 
ATOM 6021 N NE  . ARG E 5 97  ? 376.217 370.076 471.593 1.00 51.43  ? 97  ARG C NE  1 
ATOM 6022 C CZ  . ARG E 5 97  ? 376.936 369.372 472.457 1.00 51.43  ? 97  ARG C CZ  1 
ATOM 6023 N NH1 . ARG E 5 97  ? 377.830 369.977 473.220 1.00 51.43  ? 97  ARG C NH1 1 
ATOM 6024 N NH2 . ARG E 5 97  ? 376.765 368.066 472.557 1.00 51.43  ? 97  ARG C NH2 1 
ATOM 6025 N N   . THR E 5 98  ? 372.887 371.782 467.220 1.00 49.06  ? 98  THR C N   1 
ATOM 6026 C CA  . THR E 5 98  ? 371.696 371.393 466.484 1.00 49.06  ? 98  THR C CA  1 
ATOM 6027 C C   . THR E 5 98  ? 371.940 370.118 465.687 1.00 49.06  ? 98  THR C C   1 
ATOM 6028 O O   . THR E 5 98  ? 372.970 369.455 465.805 1.00 49.06  ? 98  THR C O   1 
ATOM 6029 C CB  . THR E 5 98  ? 371.238 372.513 465.558 1.00 49.06  ? 98  THR C CB  1 
ATOM 6030 O OG1 . THR E 5 98  ? 372.225 372.723 464.547 1.00 49.06  ? 98  THR C OG1 1 
ATOM 6031 C CG2 . THR E 5 98  ? 371.048 373.789 466.335 1.00 49.06  ? 98  THR C CG2 1 
ATOM 6032 N N   . LEU E 5 99  ? 370.963 369.764 464.862 1.00 46.62  ? 99  LEU C N   1 
ATOM 6033 C CA  . LEU E 5 99  ? 371.052 368.516 464.121 1.00 46.62  ? 99  LEU C CA  1 
ATOM 6034 C C   . LEU E 5 99  ? 371.982 368.652 462.934 1.00 46.62  ? 99  LEU C C   1 
ATOM 6035 O O   . LEU E 5 99  ? 372.589 367.671 462.502 1.00 46.62  ? 99  LEU C O   1 
ATOM 6036 C CB  . LEU E 5 99  ? 369.661 368.094 463.671 1.00 46.62  ? 99  LEU C CB  1 
ATOM 6037 C CG  . LEU E 5 99  ? 369.410 366.625 463.389 1.00 46.62  ? 99  LEU C CG  1 
ATOM 6038 C CD1 . LEU E 5 99  ? 369.878 365.798 464.552 1.00 46.62  ? 99  LEU C CD1 1 
ATOM 6039 C CD2 . LEU E 5 99  ? 367.940 366.460 463.222 1.00 46.62  ? 99  LEU C CD2 1 
ATOM 6040 N N   . LEU E 5 100 ? 372.103 369.858 462.399 1.00 48.99  ? 100 LEU C N   1 
ATOM 6041 C CA  . LEU E 5 100 ? 373.064 370.127 461.345 1.00 48.99  ? 100 LEU C CA  1 
ATOM 6042 C C   . LEU E 5 100 ? 374.425 370.468 461.930 1.00 48.99  ? 100 LEU C C   1 
ATOM 6043 O O   . LEU E 5 100 ? 375.452 369.983 461.454 1.00 48.99  ? 100 LEU C O   1 
ATOM 6044 C CB  . LEU E 5 100 ? 372.544 371.261 460.472 1.00 48.99  ? 100 LEU C CB  1 
ATOM 6045 C CG  . LEU E 5 100 ? 373.505 372.082 459.637 1.00 48.99  ? 100 LEU C CG  1 
ATOM 6046 C CD1 . LEU E 5 100 ? 373.942 371.313 458.428 1.00 48.99  ? 100 LEU C CD1 1 
ATOM 6047 C CD2 . LEU E 5 100 ? 372.773 373.304 459.225 1.00 48.99  ? 100 LEU C CD2 1 
ATOM 6048 N N   . GLY E 5 101 ? 374.446 371.270 462.991 1.00 49.93  ? 101 GLY C N   1 
ATOM 6049 C CA  . GLY E 5 101 ? 375.683 371.744 463.577 1.00 49.93  ? 101 GLY C CA  1 
ATOM 6050 C C   . GLY E 5 101 ? 376.522 370.692 464.273 1.00 49.93  ? 101 GLY C C   1 
ATOM 6051 O O   . GLY E 5 101 ? 377.664 370.990 464.627 1.00 49.93  ? 101 GLY C O   1 
ATOM 6052 N N   . GLU E 5 102 ? 375.997 369.488 464.491 1.00 52.54  ? 102 GLU C N   1 
ATOM 6053 C CA  . GLU E 5 102 ? 376.815 368.421 465.052 1.00 52.54  ? 102 GLU C CA  1 
ATOM 6054 C C   . GLU E 5 102 ? 377.277 367.432 464.004 1.00 52.54  ? 102 GLU C C   1 
ATOM 6055 O O   . GLU E 5 102 ? 378.083 366.553 464.317 1.00 52.54  ? 102 GLU C O   1 
ATOM 6056 C CB  . GLU E 5 102 ? 376.072 367.670 466.153 1.00 52.54  ? 102 GLU C CB  1 
ATOM 6057 C CG  . GLU E 5 102 ? 375.955 368.441 467.454 1.00 52.54  ? 102 GLU C CG  1 
ATOM 6058 C CD  . GLU E 5 102 ? 375.321 367.626 468.563 1.00 52.54  ? 102 GLU C CD  1 
ATOM 6059 O OE1 . GLU E 5 102 ? 374.849 366.510 468.280 1.00 52.54  ? 102 GLU C OE1 1 
ATOM 6060 O OE2 . GLU E 5 102 ? 375.303 368.096 469.720 1.00 52.54  ? 102 GLU C OE2 1 
ATOM 6061 N N   . ILE E 5 103 ? 376.779 367.545 462.781 1.00 48.99  ? 103 ILE C N   1 
ATOM 6062 C CA  . ILE E 5 103 ? 377.311 366.773 461.668 1.00 48.99  ? 103 ILE C CA  1 
ATOM 6063 C C   . ILE E 5 103 ? 378.458 367.514 461.001 1.00 48.99  ? 103 ILE C C   1 
ATOM 6064 O O   . ILE E 5 103 ? 379.462 366.910 460.620 1.00 48.99  ? 103 ILE C O   1 
ATOM 6065 C CB  . ILE E 5 103 ? 376.162 366.447 460.694 1.00 48.99  ? 103 ILE C CB  1 
ATOM 6066 C CG1 . ILE E 5 103 ? 375.461 365.174 461.158 1.00 48.99  ? 103 ILE C CG1 1 
ATOM 6067 C CG2 . ILE E 5 103 ? 376.625 366.313 459.262 1.00 48.99  ? 103 ILE C CG2 1 
ATOM 6068 C CD1 . ILE E 5 103 ? 374.250 364.829 460.360 1.00 48.99  ? 103 ILE C CD1 1 
ATOM 6069 N N   . LEU E 5 104 ? 378.366 368.839 460.932 1.00 51.31  ? 104 LEU C N   1 
ATOM 6070 C CA  . LEU E 5 104 ? 379.451 369.656 460.417 1.00 51.31  ? 104 LEU C CA  1 
ATOM 6071 C C   . LEU E 5 104 ? 380.662 369.692 461.334 1.00 51.31  ? 104 LEU C C   1 
ATOM 6072 O O   . LEU E 5 104 ? 381.720 370.151 460.902 1.00 51.31  ? 104 LEU C O   1 
ATOM 6073 C CB  . LEU E 5 104 ? 378.970 371.080 460.187 1.00 51.31  ? 104 LEU C CB  1 
ATOM 6074 C CG  . LEU E 5 104 ? 377.717 371.252 459.347 1.00 51.31  ? 104 LEU C CG  1 
ATOM 6075 C CD1 . LEU E 5 104 ? 377.298 372.692 459.375 1.00 51.31  ? 104 LEU C CD1 1 
ATOM 6076 C CD2 . LEU E 5 104 ? 377.985 370.806 457.940 1.00 51.31  ? 104 LEU C CD2 1 
ATOM 6077 N N   . ASN E 5 105 ? 380.542 369.249 462.577 1.00 53.61  ? 105 ASN C N   1 
ATOM 6078 C CA  . ASN E 5 105 ? 381.693 369.174 463.458 1.00 53.61  ? 105 ASN C CA  1 
ATOM 6079 C C   . ASN E 5 105 ? 382.510 367.915 463.247 1.00 53.61  ? 105 ASN C C   1 
ATOM 6080 O O   . ASN E 5 105 ? 383.591 367.792 463.826 1.00 53.61  ? 105 ASN C O   1 
ATOM 6081 C CB  . ASN E 5 105 ? 381.256 369.259 464.913 1.00 53.61  ? 105 ASN C CB  1 
ATOM 6082 C CG  . ASN E 5 105 ? 381.051 370.673 465.361 1.00 53.61  ? 105 ASN C CG  1 
ATOM 6083 O OD1 . ASN E 5 105 ? 380.514 371.494 464.624 1.00 53.61  ? 105 ASN C OD1 1 
ATOM 6084 N ND2 . ASN E 5 105 ? 381.500 370.980 466.565 1.00 53.61  ? 105 ASN C ND2 1 
ATOM 6085 N N   . TYR E 5 106 ? 382.026 366.981 462.442 1.00 52.35  ? 106 TYR C N   1 
ATOM 6086 C CA  . TYR E 5 106 ? 382.819 365.833 462.043 1.00 52.35  ? 106 TYR C CA  1 
ATOM 6087 C C   . TYR E 5 106 ? 383.653 366.100 460.805 1.00 52.35  ? 106 TYR C C   1 
ATOM 6088 O O   . TYR E 5 106 ? 384.261 365.166 460.284 1.00 52.35  ? 106 TYR C O   1 
ATOM 6089 C CB  . TYR E 5 106 ? 381.920 364.632 461.773 1.00 52.35  ? 106 TYR C CB  1 
ATOM 6090 C CG  . TYR E 5 106 ? 381.552 363.834 462.994 1.00 52.35  ? 106 TYR C CG  1 
ATOM 6091 C CD1 . TYR E 5 106 ? 382.482 363.029 463.620 1.00 52.35  ? 106 TYR C CD1 1 
ATOM 6092 C CD2 . TYR E 5 106 ? 380.266 363.869 463.505 1.00 52.35  ? 106 TYR C CD2 1 
ATOM 6093 C CE1 . TYR E 5 106 ? 382.146 362.290 464.728 1.00 52.35  ? 106 TYR C CE1 1 
ATOM 6094 C CE2 . TYR E 5 106 ? 379.921 363.133 464.613 1.00 52.35  ? 106 TYR C CE2 1 
ATOM 6095 C CZ  . TYR E 5 106 ? 380.865 362.348 465.218 1.00 52.35  ? 106 TYR C CZ  1 
ATOM 6096 O OH  . TYR E 5 106 ? 380.532 361.611 466.324 1.00 52.35  ? 106 TYR C OH  1 
ATOM 6097 N N   . TYR E 5 107 ? 383.686 367.333 460.315 1.00 53.67  ? 107 TYR C N   1 
ATOM 6098 C CA  . TYR E 5 107 ? 384.385 367.673 459.088 1.00 53.67  ? 107 TYR C CA  1 
ATOM 6099 C C   . TYR E 5 107 ? 385.155 368.967 459.279 1.00 53.67  ? 107 TYR C C   1 
ATOM 6100 O O   . TYR E 5 107 ? 384.741 369.855 460.023 1.00 53.67  ? 107 TYR C O   1 
ATOM 6101 C CB  . TYR E 5 107 ? 383.411 367.796 457.922 1.00 53.67  ? 107 TYR C CB  1 
ATOM 6102 C CG  . TYR E 5 107 ? 382.854 366.465 457.524 1.00 53.67  ? 107 TYR C CG  1 
ATOM 6103 C CD1 . TYR E 5 107 ? 383.596 365.596 456.749 1.00 53.67  ? 107 TYR C CD1 1 
ATOM 6104 C CD2 . TYR E 5 107 ? 381.606 366.060 457.948 1.00 53.67  ? 107 TYR C CD2 1 
ATOM 6105 C CE1 . TYR E 5 107 ? 383.110 364.373 456.392 1.00 53.67  ? 107 TYR C CE1 1 
ATOM 6106 C CE2 . TYR E 5 107 ? 381.106 364.832 457.595 1.00 53.67  ? 107 TYR C CE2 1 
ATOM 6107 C CZ  . TYR E 5 107 ? 381.868 363.995 456.816 1.00 53.67  ? 107 TYR C CZ  1 
ATOM 6108 O OH  . TYR E 5 107 ? 381.389 362.766 456.457 1.00 53.67  ? 107 TYR C OH  1 
ATOM 6109 N N   . THR E 5 108 ? 386.284 369.072 458.584 1.00 55.96  ? 108 THR C N   1 
ATOM 6110 C CA  . THR E 5 108 ? 387.219 370.167 458.802 1.00 55.96  ? 108 THR C CA  1 
ATOM 6111 C C   . THR E 5 108 ? 386.875 371.417 458.005 1.00 55.96  ? 108 THR C C   1 
ATOM 6112 O O   . THR E 5 108 ? 387.021 372.527 458.518 1.00 55.96  ? 108 THR C O   1 
ATOM 6113 C CB  . THR E 5 108 ? 388.640 369.720 458.461 1.00 55.96  ? 108 THR C CB  1 
ATOM 6114 O OG1 . THR E 5 108 ? 388.853 368.406 458.978 1.00 55.96  ? 108 THR C OG1 1 
ATOM 6115 C CG2 . THR E 5 108 ? 389.644 370.635 459.110 1.00 55.96  ? 108 THR C CG2 1 
ATOM 6116 N N   . HIS E 5 109 ? 386.409 371.275 456.769 1.00 58.74  ? 109 HIS C N   1 
ATOM 6117 C CA  . HIS E 5 109 ? 386.002 372.412 455.959 1.00 58.74  ? 109 HIS C CA  1 
ATOM 6118 C C   . HIS E 5 109 ? 384.644 372.141 455.333 1.00 58.74  ? 109 HIS C C   1 
ATOM 6119 O O   . HIS E 5 109 ? 384.396 371.038 454.843 1.00 58.74  ? 109 HIS C O   1 
ATOM 6120 C CB  . HIS E 5 109 ? 387.032 372.703 454.877 1.00 58.74  ? 109 HIS C CB  1 
ATOM 6121 C CG  . HIS E 5 109 ? 388.376 373.067 455.416 1.00 58.74  ? 109 HIS C CG  1 
ATOM 6122 N ND1 . HIS E 5 109 ? 389.358 372.132 455.655 1.00 58.74  ? 109 HIS C ND1 1 
ATOM 6123 C CD2 . HIS E 5 109 ? 388.898 374.263 455.773 1.00 58.74  ? 109 HIS C CD2 1 
ATOM 6124 C CE1 . HIS E 5 109 ? 390.432 372.737 456.130 1.00 58.74  ? 109 HIS C CE1 1 
ATOM 6125 N NE2 . HIS E 5 109 ? 390.179 374.030 456.213 1.00 58.74  ? 109 HIS C NE2 1 
ATOM 6126 N N   . TRP E 5 110 ? 383.774 373.146 455.347 1.00 54.03  ? 110 TRP C N   1 
ATOM 6127 C CA  . TRP E 5 110 ? 382.448 373.006 454.771 1.00 54.03  ? 110 TRP C CA  1 
ATOM 6128 C C   . TRP E 5 110 ? 381.966 374.363 454.283 1.00 54.03  ? 110 TRP C C   1 
ATOM 6129 O O   . TRP E 5 110 ? 382.482 375.399 454.701 1.00 54.03  ? 110 TRP C O   1 
ATOM 6130 C CB  . TRP E 5 110 ? 381.466 372.413 455.779 1.00 54.03  ? 110 TRP C CB  1 
ATOM 6131 C CG  . TRP E 5 110 ? 381.681 372.879 457.164 1.00 54.03  ? 110 TRP C CG  1 
ATOM 6132 C CD1 . TRP E 5 110 ? 382.410 372.264 458.128 1.00 54.03  ? 110 TRP C CD1 1 
ATOM 6133 C CD2 . TRP E 5 110 ? 381.149 374.061 457.757 1.00 54.03  ? 110 TRP C CD2 1 
ATOM 6134 N NE1 . TRP E 5 110 ? 382.376 372.991 459.285 1.00 54.03  ? 110 TRP C NE1 1 
ATOM 6135 C CE2 . TRP E 5 110 ? 381.602 374.101 459.081 1.00 54.03  ? 110 TRP C CE2 1 
ATOM 6136 C CE3 . TRP E 5 110 ? 380.333 375.090 457.294 1.00 54.03  ? 110 TRP C CE3 1 
ATOM 6137 C CZ2 . TRP E 5 110 ? 381.270 375.126 459.944 1.00 54.03  ? 110 TRP C CZ2 1 
ATOM 6138 C CZ3 . TRP E 5 110 ? 380.008 376.102 458.148 1.00 54.03  ? 110 TRP C CZ3 1 
ATOM 6139 C CH2 . TRP E 5 110 ? 380.474 376.118 459.458 1.00 54.03  ? 110 TRP C CH2 1 
ATOM 6140 N N   . SER E 5 111 ? 380.973 374.344 453.395 1.00 58.15  ? 111 SER C N   1 
ATOM 6141 C CA  . SER E 5 111 ? 380.462 375.567 452.794 1.00 58.15  ? 111 SER C CA  1 
ATOM 6142 C C   . SER E 5 111 ? 379.078 375.318 452.217 1.00 58.15  ? 111 SER C C   1 
ATOM 6143 O O   . SER E 5 111 ? 378.831 374.271 451.617 1.00 58.15  ? 111 SER C O   1 
ATOM 6144 C CB  . SER E 5 111 ? 381.385 376.069 451.687 1.00 58.15  ? 111 SER C CB  1 
ATOM 6145 O OG  . SER E 5 111 ? 381.358 375.183 450.585 1.00 58.15  ? 111 SER C OG  1 
ATOM 6146 N N   . GLY E 5 112 ? 378.194 376.293 452.376 1.00 58.27  ? 112 GLY C N   1 
ATOM 6147 C CA  . GLY E 5 112 ? 376.848 376.163 451.856 1.00 58.27  ? 112 GLY C CA  1 
ATOM 6148 C C   . GLY E 5 112 ? 375.965 377.276 452.364 1.00 58.27  ? 112 GLY C C   1 
ATOM 6149 O O   . GLY E 5 112 ? 376.447 378.350 452.719 1.00 58.27  ? 112 GLY C O   1 
ATOM 6150 N N   . SER E 5 113 ? 374.663 377.015 452.400 1.00 57.63  ? 113 SER C N   1 
ATOM 6151 C CA  . SER E 5 113 ? 373.691 378.000 452.848 1.00 57.63  ? 113 SER C CA  1 
ATOM 6152 C C   . SER E 5 113 ? 372.783 377.429 453.929 1.00 57.63  ? 113 SER C C   1 
ATOM 6153 O O   . SER E 5 113 ? 372.792 376.234 454.215 1.00 57.63  ? 113 SER C O   1 
ATOM 6154 C CB  . SER E 5 113 ? 372.846 378.496 451.681 1.00 57.63  ? 113 SER C CB  1 
ATOM 6155 O OG  . SER E 5 113 ? 371.744 377.639 451.494 1.00 57.63  ? 113 SER C OG  1 
ATOM 6156 N N   . ILE E 5 114 ? 371.979 378.305 454.520 1.00 54.53  ? 114 ILE C N   1 
ATOM 6157 C CA  . ILE E 5 114 ? 371.218 378.001 455.728 1.00 54.53  ? 114 ILE C CA  1 
ATOM 6158 C C   . ILE E 5 114 ? 369.788 378.485 455.560 1.00 54.53  ? 114 ILE C C   1 
ATOM 6159 O O   . ILE E 5 114 ? 369.560 379.655 455.242 1.00 54.53  ? 114 ILE C O   1 
ATOM 6160 C CB  . ILE E 5 114 ? 371.857 378.659 456.966 1.00 54.53  ? 114 ILE C CB  1 
ATOM 6161 C CG1 . ILE E 5 114 ? 373.164 377.991 457.313 1.00 54.53  ? 114 ILE C CG1 1 
ATOM 6162 C CG2 . ILE E 5 114 ? 370.955 378.613 458.147 1.00 54.53  ? 114 ILE C CG2 1 
ATOM 6163 C CD1 . ILE E 5 114 ? 373.009 376.556 457.571 1.00 54.53  ? 114 ILE C CD1 1 
ATOM 6164 N N   . LYS E 5 115 ? 368.825 377.599 455.778 1.00 54.96  ? 115 LYS C N   1 
ATOM 6165 C CA  . LYS E 5 115 ? 367.433 378.000 455.871 1.00 54.96  ? 115 LYS C CA  1 
ATOM 6166 C C   . LYS E 5 115 ? 367.085 378.322 457.314 1.00 54.96  ? 115 LYS C C   1 
ATOM 6167 O O   . LYS E 5 115 ? 367.217 377.472 458.194 1.00 54.96  ? 115 LYS C O   1 
ATOM 6168 C CB  . LYS E 5 115 ? 366.518 376.894 455.362 1.00 54.96  ? 115 LYS C CB  1 
ATOM 6169 C CG  . LYS E 5 115 ? 366.305 376.894 453.873 1.00 54.96  ? 115 LYS C CG  1 
ATOM 6170 C CD  . LYS E 5 115 ? 365.348 375.794 453.476 1.00 54.96  ? 115 LYS C CD  1 
ATOM 6171 C CE  . LYS E 5 115 ? 364.031 375.928 454.201 1.00 54.96  ? 115 LYS C CE  1 
ATOM 6172 N NZ  . LYS E 5 115 ? 363.182 374.731 453.990 1.00 54.96  ? 115 LYS C NZ  1 
ATOM 6173 N N   . LEU E 5 116 ? 366.620 379.543 457.553 1.00 50.31  ? 116 LEU C N   1 
ATOM 6174 C CA  . LEU E 5 116 ? 366.264 379.987 458.898 1.00 50.31  ? 116 LEU C CA  1 
ATOM 6175 C C   . LEU E 5 116 ? 364.774 380.299 458.927 1.00 50.31  ? 116 LEU C C   1 
ATOM 6176 O O   . LEU E 5 116 ? 364.355 381.382 458.515 1.00 50.31  ? 116 LEU C O   1 
ATOM 6177 C CB  . LEU E 5 116 ? 367.084 381.199 459.310 1.00 50.31  ? 116 LEU C CB  1 
ATOM 6178 C CG  . LEU E 5 116 ? 368.495 380.906 459.803 1.00 50.31  ? 116 LEU C CG  1 
ATOM 6179 C CD1 . LEU E 5 116 ? 369.249 382.188 460.015 1.00 50.31  ? 116 LEU C CD1 1 
ATOM 6180 C CD2 . LEU E 5 116 ? 368.455 380.102 461.078 1.00 50.31  ? 116 LEU C CD2 1 
ATOM 6181 N N   . THR E 5 117 ? 363.981 379.361 459.423 1.00 50.22  ? 117 THR C N   1 
ATOM 6182 C CA  . THR E 5 117 ? 362.533 379.497 459.485 1.00 50.22  ? 117 THR C CA  1 
ATOM 6183 C C   . THR E 5 117 ? 362.137 379.923 460.888 1.00 50.22  ? 117 THR C C   1 
ATOM 6184 O O   . THR E 5 117 ? 362.613 379.346 461.867 1.00 50.22  ? 117 THR C O   1 
ATOM 6185 C CB  . THR E 5 117 ? 361.858 378.173 459.120 1.00 50.22  ? 117 THR C CB  1 
ATOM 6186 O OG1 . THR E 5 117 ? 362.169 377.834 457.765 1.00 50.22  ? 117 THR C OG1 1 
ATOM 6187 C CG2 . THR E 5 117 ? 360.356 378.254 459.270 1.00 50.22  ? 117 THR C CG2 1 
ATOM 6188 N N   . PHE E 5 118 ? 361.286 380.935 460.985 1.00 48.17  ? 118 PHE C N   1 
ATOM 6189 C CA  . PHE E 5 118 ? 360.735 381.380 462.252 1.00 48.17  ? 118 PHE C CA  1 
ATOM 6190 C C   . PHE E 5 118 ? 359.264 381.008 462.335 1.00 48.17  ? 118 PHE C C   1 
ATOM 6191 O O   . PHE E 5 118 ? 358.609 380.761 461.325 1.00 48.17  ? 118 PHE C O   1 
ATOM 6192 C CB  . PHE E 5 118 ? 360.904 382.887 462.420 1.00 48.17  ? 118 PHE C CB  1 
ATOM 6193 C CG  . PHE E 5 118 ? 362.318 383.328 462.375 1.00 48.17  ? 118 PHE C CG  1 
ATOM 6194 C CD1 . PHE E 5 118 ? 363.107 383.253 463.499 1.00 48.17  ? 118 PHE C CD1 1 
ATOM 6195 C CD2 . PHE E 5 118 ? 362.868 383.805 461.202 1.00 48.17  ? 118 PHE C CD2 1 
ATOM 6196 C CE1 . PHE E 5 118 ? 364.414 383.647 463.457 1.00 48.17  ? 118 PHE C CE1 1 
ATOM 6197 C CE2 . PHE E 5 118 ? 364.180 384.202 461.156 1.00 48.17  ? 118 PHE C CE2 1 
ATOM 6198 C CZ  . PHE E 5 118 ? 364.953 384.125 462.286 1.00 48.17  ? 118 PHE C CZ  1 
ATOM 6199 N N   . MET E 5 119 ? 358.745 380.962 463.555 1.00 48.98  ? 119 MET C N   1 
ATOM 6200 C CA  . MET E 5 119 ? 357.342 380.630 463.750 1.00 48.98  ? 119 MET C CA  1 
ATOM 6201 C C   . MET E 5 119 ? 356.806 381.415 464.931 1.00 48.98  ? 119 MET C C   1 
ATOM 6202 O O   . MET E 5 119 ? 357.335 381.309 466.038 1.00 48.98  ? 119 MET C O   1 
ATOM 6203 C CB  . MET E 5 119 ? 357.150 379.131 463.976 1.00 48.98  ? 119 MET C CB  1 
ATOM 6204 C CG  . MET E 5 119 ? 355.733 378.665 463.743 1.00 48.98  ? 119 MET C CG  1 
ATOM 6205 S SD  . MET E 5 119 ? 355.561 376.876 463.749 1.00 48.98  ? 119 MET C SD  1 
ATOM 6206 C CE  . MET E 5 119 ? 356.215 376.501 465.365 1.00 48.98  ? 119 MET C CE  1 
ATOM 6207 N N   . PHE E 5 120 ? 355.762 382.196 464.692 1.00 46.69  ? 120 PHE C N   1 
ATOM 6208 C CA  . PHE E 5 120 ? 355.146 383.008 465.730 1.00 46.69  ? 120 PHE C CA  1 
ATOM 6209 C C   . PHE E 5 120 ? 354.153 382.148 466.494 1.00 46.69  ? 120 PHE C C   1 
ATOM 6210 O O   . PHE E 5 120 ? 353.086 381.814 465.977 1.00 46.69  ? 120 PHE C O   1 
ATOM 6211 C CB  . PHE E 5 120 ? 354.456 384.222 465.126 1.00 46.69  ? 120 PHE C CB  1 
ATOM 6212 C CG  . PHE E 5 120 ? 353.952 385.188 466.141 1.00 46.69  ? 120 PHE C CG  1 
ATOM 6213 C CD1 . PHE E 5 120 ? 354.817 386.048 466.778 1.00 46.69  ? 120 PHE C CD1 1 
ATOM 6214 C CD2 . PHE E 5 120 ? 352.615 385.234 466.465 1.00 46.69  ? 120 PHE C CD2 1 
ATOM 6215 C CE1 . PHE E 5 120 ? 354.356 386.938 467.714 1.00 46.69  ? 120 PHE C CE1 1 
ATOM 6216 C CE2 . PHE E 5 120 ? 352.151 386.128 467.392 1.00 46.69  ? 120 PHE C CE2 1 
ATOM 6217 C CZ  . PHE E 5 120 ? 353.023 386.977 468.019 1.00 46.69  ? 120 PHE C CZ  1 
ATOM 6218 N N   . CYS E 5 121 ? 354.505 381.784 467.718 1.00 49.96  ? 121 CYS C N   1 
ATOM 6219 C CA  . CYS E 5 121 ? 353.639 380.966 468.560 1.00 49.96  ? 121 CYS C CA  1 
ATOM 6220 C C   . CYS E 5 121 ? 352.872 381.842 469.544 1.00 49.96  ? 121 CYS C C   1 
ATOM 6221 O O   . CYS E 5 121 ? 353.010 381.735 470.756 1.00 49.96  ? 121 CYS C O   1 
ATOM 6222 C CB  . CYS E 5 121 ? 354.463 379.919 469.287 1.00 49.96  ? 121 CYS C CB  1 
ATOM 6223 S SG  . CYS E 5 121 ? 355.103 378.642 468.214 1.00 49.96  ? 121 CYS C SG  1 
ATOM 6224 N N   . GLY E 5 122 ? 352.047 382.720 468.993 1.00 48.89  ? 122 GLY C N   1 
ATOM 6225 C CA  . GLY E 5 122 ? 351.244 383.601 469.809 1.00 48.89  ? 122 GLY C CA  1 
ATOM 6226 C C   . GLY E 5 122 ? 349.769 383.417 469.546 1.00 48.89  ? 122 GLY C C   1 
ATOM 6227 O O   . GLY E 5 122 ? 349.361 382.392 468.998 1.00 48.89  ? 122 GLY C O   1 
ATOM 6228 N N   . SER E 5 123 ? 348.961 384.400 469.924 1.00 49.50  ? 123 SER C N   1 
ATOM 6229 C CA  . SER E 5 123 ? 347.525 384.283 469.761 1.00 49.50  ? 123 SER C CA  1 
ATOM 6230 C C   . SER E 5 123 ? 347.131 384.507 468.309 1.00 49.50  ? 123 SER C C   1 
ATOM 6231 O O   . SER E 5 123 ? 347.880 385.071 467.511 1.00 49.50  ? 123 SER C O   1 
ATOM 6232 C CB  . SER E 5 123 ? 346.798 385.276 470.655 1.00 49.50  ? 123 SER C CB  1 
ATOM 6233 O OG  . SER E 5 123 ? 345.409 385.030 470.629 1.00 49.50  ? 123 SER C OG  1 
ATOM 6234 N N   . ALA E 5 124 ? 345.934 384.052 467.967 1.00 50.96  ? 124 ALA C N   1 
ATOM 6235 C CA  . ALA E 5 124 ? 345.431 384.186 466.611 1.00 50.96  ? 124 ALA C CA  1 
ATOM 6236 C C   . ALA E 5 124 ? 344.786 385.534 466.357 1.00 50.96  ? 124 ALA C C   1 
ATOM 6237 O O   . ALA E 5 124 ? 344.446 385.835 465.212 1.00 50.96  ? 124 ALA C O   1 
ATOM 6238 C CB  . ALA E 5 124 ? 344.428 383.076 466.312 1.00 50.96  ? 124 ALA C CB  1 
ATOM 6239 N N   . MET E 5 125 ? 344.615 386.346 467.395 1.00 53.97  ? 125 MET C N   1 
ATOM 6240 C CA  . MET E 5 125 ? 344.006 387.660 467.290 1.00 53.97  ? 125 MET C CA  1 
ATOM 6241 C C   . MET E 5 125 ? 345.030 388.782 467.251 1.00 53.97  ? 125 MET C C   1 
ATOM 6242 O O   . MET E 5 125 ? 344.640 389.948 467.174 1.00 53.97  ? 125 MET C O   1 
ATOM 6243 C CB  . MET E 5 125 ? 343.058 387.890 468.471 1.00 53.97  ? 125 MET C CB  1 
ATOM 6244 C CG  . MET E 5 125 ? 341.844 386.984 468.526 1.00 53.97  ? 125 MET C CG  1 
ATOM 6245 S SD  . MET E 5 125 ? 340.578 387.419 467.328 1.00 53.97  ? 125 MET C SD  1 
ATOM 6246 C CE  . MET E 5 125 ? 339.368 386.146 467.645 1.00 53.97  ? 125 MET C CE  1 
ATOM 6247 N N   . ALA E 5 126 ? 346.320 388.469 467.305 1.00 53.44  ? 126 ALA C N   1 
ATOM 6248 C CA  . ALA E 5 126 ? 347.359 389.481 467.428 1.00 53.44  ? 126 ALA C CA  1 
ATOM 6249 C C   . ALA E 5 126 ? 347.909 389.875 466.064 1.00 53.44  ? 126 ALA C C   1 
ATOM 6250 O O   . ALA E 5 126 ? 347.895 389.081 465.122 1.00 53.44  ? 126 ALA C O   1 
ATOM 6251 C CB  . ALA E 5 126 ? 348.492 388.978 468.317 1.00 53.44  ? 126 ALA C CB  1 
ATOM 6252 N N   . THR E 5 127 ? 348.395 391.109 465.967 1.00 55.43  ? 127 THR C N   1 
ATOM 6253 C CA  . THR E 5 127 ? 348.908 391.652 464.718 1.00 55.43  ? 127 THR C CA  1 
ATOM 6254 C C   . THR E 5 127 ? 350.169 392.453 464.996 1.00 55.43  ? 127 THR C C   1 
ATOM 6255 O O   . THR E 5 127 ? 350.212 393.238 465.946 1.00 55.43  ? 127 THR C O   1 
ATOM 6256 C CB  . THR E 5 127 ? 347.875 392.549 464.030 1.00 55.43  ? 127 THR C CB  1 
ATOM 6257 O OG1 . THR E 5 127 ? 346.591 391.919 464.064 1.00 55.43  ? 127 THR C OG1 1 
ATOM 6258 C CG2 . THR E 5 127 ? 348.258 392.795 462.585 1.00 55.43  ? 127 THR C CG2 1 
ATOM 6259 N N   . GLY E 5 128 ? 351.188 392.253 464.171 1.00 52.17  ? 128 GLY C N   1 
ATOM 6260 C CA  . GLY E 5 128 ? 352.418 392.998 464.330 1.00 52.17  ? 128 GLY C CA  1 
ATOM 6261 C C   . GLY E 5 128 ? 353.299 392.874 463.109 1.00 52.17  ? 128 GLY C C   1 
ATOM 6262 O O   . GLY E 5 128 ? 352.977 392.169 462.155 1.00 52.17  ? 128 GLY C O   1 
ATOM 6263 N N   . LYS E 5 129 ? 354.422 393.582 463.151 1.00 50.69  ? 129 LYS C N   1 
ATOM 6264 C CA  . LYS E 5 129 ? 355.402 393.533 462.082 1.00 50.69  ? 129 LYS C CA  1 
ATOM 6265 C C   . LYS E 5 129 ? 356.791 393.396 462.681 1.00 50.69  ? 129 LYS C C   1 
ATOM 6266 O O   . LYS E 5 129 ? 357.052 393.856 463.792 1.00 50.69  ? 129 LYS C O   1 
ATOM 6267 C CB  . LYS E 5 129 ? 355.340 394.774 461.197 1.00 50.69  ? 129 LYS C CB  1 
ATOM 6268 C CG  . LYS E 5 129 ? 354.367 394.663 460.057 1.00 50.69  ? 129 LYS C CG  1 
ATOM 6269 C CD  . LYS E 5 129 ? 354.708 395.646 458.970 1.00 50.69  ? 129 LYS C CD  1 
ATOM 6270 C CE  . LYS E 5 129 ? 353.473 396.070 458.215 1.00 50.69  ? 129 LYS C CE  1 
ATOM 6271 N NZ  . LYS E 5 129 ? 352.821 394.928 457.541 1.00 50.69  ? 129 LYS C NZ  1 
ATOM 6272 N N   . PHE E 5 130 ? 357.679 392.750 461.931 1.00 50.57  ? 130 PHE C N   1 
ATOM 6273 C CA  . PHE E 5 130 ? 359.055 392.546 462.346 1.00 50.57  ? 130 PHE C CA  1 
ATOM 6274 C C   . PHE E 5 130 ? 359.975 392.797 461.164 1.00 50.57  ? 130 PHE C C   1 
ATOM 6275 O O   . PHE E 5 130 ? 359.562 392.688 460.010 1.00 50.57  ? 130 PHE C O   1 
ATOM 6276 C CB  . PHE E 5 130 ? 359.287 391.125 462.862 1.00 50.57  ? 130 PHE C CB  1 
ATOM 6277 C CG  . PHE E 5 130 ? 358.609 390.827 464.162 1.00 50.57  ? 130 PHE C CG  1 
ATOM 6278 C CD1 . PHE E 5 130 ? 359.123 391.304 465.348 1.00 50.57  ? 130 PHE C CD1 1 
ATOM 6279 C CD2 . PHE E 5 130 ? 357.471 390.046 464.198 1.00 50.57  ? 130 PHE C CD2 1 
ATOM 6280 C CE1 . PHE E 5 130 ? 358.503 391.026 466.544 1.00 50.57  ? 130 PHE C CE1 1 
ATOM 6281 C CE2 . PHE E 5 130 ? 356.853 389.764 465.391 1.00 50.57  ? 130 PHE C CE2 1 
ATOM 6282 C CZ  . PHE E 5 130 ? 357.368 390.255 466.562 1.00 50.57  ? 130 PHE C CZ  1 
ATOM 6283 N N   . LEU E 5 131 ? 361.222 393.141 461.457 1.00 52.20  ? 131 LEU C N   1 
ATOM 6284 C CA  . LEU E 5 131 ? 362.276 393.108 460.458 1.00 52.20  ? 131 LEU C CA  1 
ATOM 6285 C C   . LEU E 5 131 ? 363.124 391.865 460.654 1.00 52.20  ? 131 LEU C C   1 
ATOM 6286 O O   . LEU E 5 131 ? 363.227 391.331 461.757 1.00 52.20  ? 131 LEU C O   1 
ATOM 6287 C CB  . LEU E 5 131 ? 363.178 394.335 460.538 1.00 52.20  ? 131 LEU C CB  1 
ATOM 6288 C CG  . LEU E 5 131 ? 362.730 395.645 459.920 1.00 52.20  ? 131 LEU C CG  1 
ATOM 6289 C CD1 . LEU E 5 131 ? 363.804 396.666 460.142 1.00 52.20  ? 131 LEU C CD1 1 
ATOM 6290 C CD2 . LEU E 5 131 ? 362.493 395.460 458.455 1.00 52.20  ? 131 LEU C CD2 1 
ATOM 6291 N N   . LEU E 5 132 ? 363.737 391.407 459.572 1.00 52.53  ? 132 LEU C N   1 
ATOM 6292 C CA  . LEU E 5 132 ? 364.656 390.273 459.613 1.00 52.53  ? 132 LEU C CA  1 
ATOM 6293 C C   . LEU E 5 132 ? 365.852 390.649 458.754 1.00 52.53  ? 132 LEU C C   1 
ATOM 6294 O O   . LEU E 5 132 ? 365.859 390.412 457.549 1.00 52.53  ? 132 LEU C O   1 
ATOM 6295 C CB  . LEU E 5 132 ? 363.982 389.003 459.127 1.00 52.53  ? 132 LEU C CB  1 
ATOM 6296 C CG  . LEU E 5 132 ? 362.905 388.424 460.039 1.00 52.53  ? 132 LEU C CG  1 
ATOM 6297 C CD1 . LEU E 5 132 ? 362.204 387.266 459.375 1.00 52.53  ? 132 LEU C CD1 1 
ATOM 6298 C CD2 . LEU E 5 132 ? 363.519 388.004 461.352 1.00 52.53  ? 132 LEU C CD2 1 
ATOM 6299 N N   . ALA E 5 133 ? 366.870 391.228 459.375 1.00 53.10  ? 133 ALA C N   1 
ATOM 6300 C CA  . ALA E 5 133 ? 367.997 391.714 458.605 1.00 53.10  ? 133 ALA C CA  1 
ATOM 6301 C C   . ALA E 5 133 ? 369.157 390.731 458.645 1.00 53.10  ? 133 ALA C C   1 
ATOM 6302 O O   . ALA E 5 133 ? 369.374 390.025 459.627 1.00 53.10  ? 133 ALA C O   1 
ATOM 6303 C CB  . ALA E 5 133 ? 368.453 393.071 459.127 1.00 53.10  ? 133 ALA C CB  1 
ATOM 6304 N N   . TYR E 5 134 ? 369.920 390.709 457.557 1.00 56.31  ? 134 TYR C N   1 
ATOM 6305 C CA  . TYR E 5 134 ? 371.123 389.894 457.461 1.00 56.31  ? 134 TYR C CA  1 
ATOM 6306 C C   . TYR E 5 134 ? 372.281 390.796 457.076 1.00 56.31  ? 134 TYR C C   1 
ATOM 6307 O O   . TYR E 5 134 ? 372.309 391.329 455.965 1.00 56.31  ? 134 TYR C O   1 
ATOM 6308 C CB  . TYR E 5 134 ? 370.961 388.769 456.438 1.00 56.31  ? 134 TYR C CB  1 
ATOM 6309 C CG  . TYR E 5 134 ? 372.266 388.150 455.997 1.00 56.31  ? 134 TYR C CG  1 
ATOM 6310 C CD1 . TYR E 5 134 ? 373.122 387.554 456.915 1.00 56.31  ? 134 TYR C CD1 1 
ATOM 6311 C CD2 . TYR E 5 134 ? 372.640 388.157 454.663 1.00 56.31  ? 134 TYR C CD2 1 
ATOM 6312 C CE1 . TYR E 5 134 ? 374.318 387.003 456.520 1.00 56.31  ? 134 TYR C CE1 1 
ATOM 6313 C CE2 . TYR E 5 134 ? 373.832 387.596 454.254 1.00 56.31  ? 134 TYR C CE2 1 
ATOM 6314 C CZ  . TYR E 5 134 ? 374.664 387.016 455.189 1.00 56.31  ? 134 TYR C CZ  1 
ATOM 6315 O OH  . TYR E 5 134 ? 375.854 386.453 454.796 1.00 56.31  ? 134 TYR C OH  1 
ATOM 6316 N N   . SER E 5 135 ? 373.219 390.952 457.970 1.00 57.21  ? 135 SER C N   1 
ATOM 6317 C CA  . SER E 5 135 ? 374.412 391.730 457.693 1.00 57.21  ? 135 SER C CA  1 
ATOM 6318 C C   . SER E 5 135 ? 375.468 390.842 457.068 1.00 57.21  ? 135 SER C C   1 
ATOM 6319 O O   . SER E 5 135 ? 375.865 389.846 457.684 1.00 57.21  ? 135 SER C O   1 
ATOM 6320 C CB  . SER E 5 135 ? 374.954 392.341 458.975 1.00 57.21  ? 135 SER C CB  1 
ATOM 6321 O OG  . SER E 5 135 ? 374.012 393.227 459.540 1.00 57.21  ? 135 SER C OG  1 
ATOM 6322 N N   . PRO E 5 136 ? 375.943 391.153 455.867 1.00 60.32  ? 136 PRO C N   1 
ATOM 6323 C CA  . PRO E 5 136 ? 376.986 390.344 455.243 1.00 60.32  ? 136 PRO C CA  1 
ATOM 6324 C C   . PRO E 5 136 ? 378.312 390.548 455.950 1.00 60.32  ? 136 PRO C C   1 
ATOM 6325 O O   . PRO E 5 136 ? 378.462 391.520 456.705 1.00 60.32  ? 136 PRO C O   1 
ATOM 6326 C CB  . PRO E 5 136 ? 377.026 390.883 453.804 1.00 60.32  ? 136 PRO C CB  1 
ATOM 6327 C CG  . PRO E 5 136 ? 375.742 391.591 453.623 1.00 60.32  ? 136 PRO C CG  1 
ATOM 6328 C CD  . PRO E 5 136 ? 375.446 392.185 454.952 1.00 60.32  ? 136 PRO C CD  1 
ATOM 6329 N N   . PRO E 5 137 ? 379.280 389.644 455.769 1.00 62.81  ? 137 PRO C N   1 
ATOM 6330 C CA  . PRO E 5 137 ? 380.586 389.814 456.424 1.00 62.81  ? 137 PRO C CA  1 
ATOM 6331 C C   . PRO E 5 137 ? 381.317 391.034 455.887 1.00 62.81  ? 137 PRO C C   1 
ATOM 6332 O O   . PRO E 5 137 ? 381.500 391.188 454.680 1.00 62.81  ? 137 PRO C O   1 
ATOM 6333 C CB  . PRO E 5 137 ? 381.324 388.515 456.086 1.00 62.81  ? 137 PRO C CB  1 
ATOM 6334 C CG  . PRO E 5 137 ? 380.595 387.950 454.941 1.00 62.81  ? 137 PRO C CG  1 
ATOM 6335 C CD  . PRO E 5 137 ? 379.179 388.321 455.135 1.00 62.81  ? 137 PRO C CD  1 
ATOM 6336 N N   . GLY E 5 138 ? 381.721 391.906 456.802 1.00 67.54  ? 138 GLY C N   1 
ATOM 6337 C CA  . GLY E 5 138 ? 382.309 393.181 456.458 1.00 67.54  ? 138 GLY C CA  1 
ATOM 6338 C C   . GLY E 5 138 ? 381.515 394.330 457.037 1.00 67.54  ? 138 GLY C C   1 
ATOM 6339 O O   . GLY E 5 138 ? 382.085 395.255 457.618 1.00 67.54  ? 138 GLY C O   1 
ATOM 6340 N N   . ALA E 5 139 ? 380.196 394.273 456.907 1.00 66.67  ? 139 ALA C N   1 
ATOM 6341 C CA  . ALA E 5 139 ? 379.347 395.291 457.501 1.00 66.67  ? 139 ALA C CA  1 
ATOM 6342 C C   . ALA E 5 139 ? 379.087 394.963 458.961 1.00 66.67  ? 139 ALA C C   1 
ATOM 6343 O O   . ALA E 5 139 ? 378.916 393.802 459.336 1.00 66.67  ? 139 ALA C O   1 
ATOM 6344 C CB  . ALA E 5 139 ? 378.022 395.400 456.750 1.00 66.67  ? 139 ALA C CB  1 
ATOM 6345 N N   . GLY E 5 140 ? 379.054 396.000 459.786 1.00 65.09  ? 140 GLY C N   1 
ATOM 6346 C CA  . GLY E 5 140 ? 378.876 395.805 461.206 1.00 65.09  ? 140 GLY C CA  1 
ATOM 6347 C C   . GLY E 5 140 ? 377.456 395.435 461.570 1.00 65.09  ? 140 GLY C C   1 
ATOM 6348 O O   . GLY E 5 140 ? 376.564 395.362 460.727 1.00 65.09  ? 140 GLY C O   1 
ATOM 6349 N N   . VAL E 5 141 ? 377.257 395.169 462.852 1.00 61.23  ? 141 VAL C N   1 
ATOM 6350 C CA  . VAL E 5 141 ? 375.893 394.998 463.361 1.00 61.23  ? 141 VAL C CA  1 
ATOM 6351 C C   . VAL E 5 141 ? 375.168 396.337 463.305 1.00 61.23  ? 141 VAL C C   1 
ATOM 6352 O O   . VAL E 5 141 ? 375.745 397.367 463.698 1.00 61.23  ? 141 VAL C O   1 
ATOM 6353 C CB  . VAL E 5 141 ? 375.922 394.413 464.781 1.00 61.23  ? 141 VAL C CB  1 
ATOM 6354 C CG1 . VAL E 5 141 ? 376.890 395.151 465.689 1.00 61.23  ? 141 VAL C CG1 1 
ATOM 6355 C CG2 . VAL E 5 141 ? 374.546 394.437 465.397 1.00 61.23  ? 141 VAL C CG2 1 
ATOM 6356 N N   . PRO E 5 142 ? 373.965 396.401 462.738 1.00 59.10  ? 142 PRO C N   1 
ATOM 6357 C CA  . PRO E 5 142 ? 373.258 397.681 462.677 1.00 59.10  ? 142 PRO C CA  1 
ATOM 6358 C C   . PRO E 5 142 ? 372.781 398.098 464.054 1.00 59.10  ? 142 PRO C C   1 
ATOM 6359 O O   . PRO E 5 142 ? 372.225 397.299 464.807 1.00 59.10  ? 142 PRO C O   1 
ATOM 6360 C CB  . PRO E 5 142 ? 372.085 397.395 461.737 1.00 59.10  ? 142 PRO C CB  1 
ATOM 6361 C CG  . PRO E 5 142 ? 371.887 395.943 461.808 1.00 59.10  ? 142 PRO C CG  1 
ATOM 6362 C CD  . PRO E 5 142 ? 373.234 395.340 462.030 1.00 59.10  ? 142 PRO C CD  1 
ATOM 6363 N N   . LYS E 5 143 ? 373.032 399.359 464.389 1.00 60.18  ? 143 LYS C N   1 
ATOM 6364 C CA  . LYS E 5 143 ? 372.711 399.888 465.703 1.00 60.18  ? 143 LYS C CA  1 
ATOM 6365 C C   . LYS E 5 143 ? 371.358 400.577 465.745 1.00 60.18  ? 143 LYS C C   1 
ATOM 6366 O O   . LYS E 5 143 ? 371.021 401.194 466.758 1.00 60.18  ? 143 LYS C O   1 
ATOM 6367 C CB  . LYS E 5 143 ? 373.802 400.853 466.155 1.00 60.18  ? 143 LYS C CB  1 
ATOM 6368 C CG  . LYS E 5 143 ? 374.131 401.936 465.149 1.00 60.18  ? 143 LYS C CG  1 
ATOM 6369 C CD  . LYS E 5 143 ? 374.967 403.044 465.777 1.00 60.18  ? 143 LYS C CD  1 
ATOM 6370 C CE  . LYS E 5 143 ? 376.205 402.490 466.478 1.00 60.18  ? 143 LYS C CE  1 
ATOM 6371 N NZ  . LYS E 5 143 ? 377.342 403.449 466.482 1.00 60.18  ? 143 LYS C NZ  1 
ATOM 6372 N N   . ASN E 5 144 ? 370.570 400.475 464.681 1.00 60.32  ? 144 ASN C N   1 
ATOM 6373 C CA  . ASN E 5 144 ? 369.285 401.149 464.636 1.00 60.32  ? 144 ASN C CA  1 
ATOM 6374 C C   . ASN E 5 144 ? 368.375 400.398 463.680 1.00 60.32  ? 144 ASN C C   1 
ATOM 6375 O O   . ASN E 5 144 ? 368.822 399.546 462.913 1.00 60.32  ? 144 ASN C O   1 
ATOM 6376 C CB  . ASN E 5 144 ? 369.442 402.605 464.207 1.00 60.32  ? 144 ASN C CB  1 
ATOM 6377 C CG  . ASN E 5 144 ? 368.343 403.479 464.734 1.00 60.32  ? 144 ASN C CG  1 
ATOM 6378 O OD1 . ASN E 5 144 ? 367.252 403.002 465.045 1.00 60.32  ? 144 ASN C OD1 1 
ATOM 6379 N ND2 . ASN E 5 144 ? 368.621 404.770 464.850 1.00 60.32  ? 144 ASN C ND2 1 
ATOM 6380 N N   . ARG E 5 145 ? 367.082 400.712 463.750 1.00 59.00  ? 145 ARG C N   1 
ATOM 6381 C CA  . ARG E 5 145 ? 366.138 400.115 462.815 1.00 59.00  ? 145 ARG C CA  1 
ATOM 6382 C C   . ARG E 5 145 ? 366.317 400.681 461.418 1.00 59.00  ? 145 ARG C C   1 
ATOM 6383 O O   . ARG E 5 145 ? 366.074 399.979 460.432 1.00 59.00  ? 145 ARG C O   1 
ATOM 6384 C CB  . ARG E 5 145 ? 364.707 400.342 463.296 1.00 59.00  ? 145 ARG C CB  1 
ATOM 6385 C CG  . ARG E 5 145 ? 363.649 399.559 462.544 1.00 59.00  ? 145 ARG C CG  1 
ATOM 6386 C CD  . ARG E 5 145 ? 362.320 400.289 462.520 1.00 59.00  ? 145 ARG C CD  1 
ATOM 6387 N NE  . ARG E 5 145 ? 362.409 401.576 461.839 1.00 59.00  ? 145 ARG C NE  1 
ATOM 6388 C CZ  . ARG E 5 145 ? 362.141 401.765 460.551 1.00 59.00  ? 145 ARG C CZ  1 
ATOM 6389 N NH1 . ARG E 5 145 ? 362.250 402.974 460.025 1.00 59.00  ? 145 ARG C NH1 1 
ATOM 6390 N NH2 . ARG E 5 145 ? 361.764 400.750 459.790 1.00 59.00  ? 145 ARG C NH2 1 
ATOM 6391 N N   . LYS E 5 146 ? 366.767 401.932 461.312 1.00 61.26  ? 146 LYS C N   1 
ATOM 6392 C CA  . LYS E 5 146 ? 366.787 402.600 460.017 1.00 61.26  ? 146 LYS C CA  1 
ATOM 6393 C C   . LYS E 5 146 ? 367.922 402.094 459.143 1.00 61.26  ? 146 LYS C C   1 
ATOM 6394 O O   . LYS E 5 146 ? 367.727 401.838 457.953 1.00 61.26  ? 146 LYS C O   1 
ATOM 6395 C CB  . LYS E 5 146 ? 366.894 404.108 460.197 1.00 61.26  ? 146 LYS C CB  1 
ATOM 6396 C CG  . LYS E 5 146 ? 366.554 404.857 458.927 1.00 61.26  ? 146 LYS C CG  1 
ATOM 6397 C CD  . LYS E 5 146 ? 367.115 406.259 458.925 1.00 61.26  ? 146 LYS C CD  1 
ATOM 6398 C CE  . LYS E 5 146 ? 366.764 406.970 457.636 1.00 61.26  ? 146 LYS C CE  1 
ATOM 6399 N NZ  . LYS E 5 146 ? 367.303 408.353 457.624 1.00 61.26  ? 146 LYS C NZ  1 
ATOM 6400 N N   . ASP E 5 147 ? 369.119 401.950 459.701 1.00 61.93  ? 147 ASP C N   1 
ATOM 6401 C CA  . ASP E 5 147 ? 370.200 401.425 458.881 1.00 61.93  ? 147 ASP C CA  1 
ATOM 6402 C C   . ASP E 5 147 ? 370.137 399.916 458.729 1.00 61.93  ? 147 ASP C C   1 
ATOM 6403 O O   . ASP E 5 147 ? 370.772 399.376 457.818 1.00 61.93  ? 147 ASP C O   1 
ATOM 6404 C CB  . ASP E 5 147 ? 371.559 401.839 459.440 1.00 61.93  ? 147 ASP C CB  1 
ATOM 6405 C CG  . ASP E 5 147 ? 371.764 401.391 460.850 1.00 61.93  ? 147 ASP C CG  1 
ATOM 6406 O OD1 . ASP E 5 147 ? 370.760 401.134 461.533 1.00 61.93  ? 147 ASP C OD1 1 
ATOM 6407 O OD2 . ASP E 5 147 ? 372.932 401.302 461.280 1.00 61.93  ? 147 ASP C OD2 1 
ATOM 6408 N N   . ALA E 5 148 ? 369.387 399.226 459.585 1.00 58.11  ? 148 ALA C N   1 
ATOM 6409 C CA  . ALA E 5 148 ? 369.081 397.826 459.330 1.00 58.11  ? 148 ALA C CA  1 
ATOM 6410 C C   . ALA E 5 148 ? 368.079 397.672 458.201 1.00 58.11  ? 148 ALA C C   1 
ATOM 6411 O O   . ALA E 5 148 ? 368.007 396.606 457.585 1.00 58.11  ? 148 ALA C O   1 
ATOM 6412 C CB  . ALA E 5 148 ? 368.536 397.161 460.587 1.00 58.11  ? 148 ALA C CB  1 
ATOM 6413 N N   . MET E 5 149 ? 367.293 398.713 457.931 1.00 60.14  ? 149 MET C N   1 
ATOM 6414 C CA  . MET E 5 149 ? 366.355 398.669 456.820 1.00 60.14  ? 149 MET C CA  1 
ATOM 6415 C C   . MET E 5 149 ? 367.075 398.735 455.485 1.00 60.14  ? 149 MET C C   1 
ATOM 6416 O O   . MET E 5 149 ? 366.674 398.063 454.531 1.00 60.14  ? 149 MET C O   1 
ATOM 6417 C CB  . MET E 5 149 ? 365.349 399.812 456.949 1.00 60.14  ? 149 MET C CB  1 
ATOM 6418 C CG  . MET E 5 149 ? 364.358 399.920 455.820 1.00 60.14  ? 149 MET C CG  1 
ATOM 6419 S SD  . MET E 5 149 ? 364.642 401.377 454.806 1.00 60.14  ? 149 MET C SD  1 
ATOM 6420 C CE  . MET E 5 149 ? 364.020 402.665 455.874 1.00 60.14  ? 149 MET C CE  1 
ATOM 6421 N N   . LEU E 5 150 ? 368.160 399.498 455.403 1.00 60.59  ? 150 LEU C N   1 
ATOM 6422 C CA  . LEU E 5 150 ? 368.807 399.743 454.123 1.00 60.59  ? 150 LEU C CA  1 
ATOM 6423 C C   . LEU E 5 150 ? 369.607 398.554 453.615 1.00 60.59  ? 150 LEU C C   1 
ATOM 6424 O O   . LEU E 5 150 ? 370.008 398.560 452.448 1.00 60.59  ? 150 LEU C O   1 
ATOM 6425 C CB  . LEU E 5 150 ? 369.701 400.977 454.231 1.00 60.59  ? 150 LEU C CB  1 
ATOM 6426 C CG  . LEU E 5 150 ? 368.985 402.176 454.854 1.00 60.59  ? 150 LEU C CG  1 
ATOM 6427 C CD1 . LEU E 5 150 ? 369.961 403.233 455.295 1.00 60.59  ? 150 LEU C CD1 1 
ATOM 6428 C CD2 . LEU E 5 150 ? 367.997 402.756 453.880 1.00 60.59  ? 150 LEU C CD2 1 
ATOM 6429 N N   . GLY E 5 151 ? 369.843 397.544 454.440 1.00 60.70  ? 151 GLY C N   1 
ATOM 6430 C CA  . GLY E 5 151 ? 370.472 396.308 454.012 1.00 60.70  ? 151 GLY C CA  1 
ATOM 6431 C C   . GLY E 5 151 ? 369.457 395.321 453.482 1.00 60.70  ? 151 GLY C C   1 
ATOM 6432 O O   . GLY E 5 151 ? 368.329 395.683 453.139 1.00 60.70  ? 151 GLY C O   1 
ATOM 6433 N N   . THR E 5 152 ? 369.854 394.056 453.410 1.00 58.52  ? 152 THR C N   1 
ATOM 6434 C CA  . THR E 5 152 ? 368.928 393.006 453.016 1.00 58.52  ? 152 THR C CA  1 
ATOM 6435 C C   . THR E 5 152 ? 368.022 392.690 454.191 1.00 58.52  ? 152 THR C C   1 
ATOM 6436 O O   . THR E 5 152 ? 368.496 392.450 455.302 1.00 58.52  ? 152 THR C O   1 
ATOM 6437 C CB  . THR E 5 152 ? 369.661 391.739 452.591 1.00 58.52  ? 152 THR C CB  1 
ATOM 6438 O OG1 . THR E 5 152 ? 370.175 391.089 453.753 1.00 58.52  ? 152 THR C OG1 1 
ATOM 6439 C CG2 . THR E 5 152 ? 370.808 392.081 451.674 1.00 58.52  ? 152 THR C CG2 1 
ATOM 6440 N N   . HIS E 5 153 ? 366.719 392.682 453.943 1.00 55.10  ? 153 HIS C N   1 
ATOM 6441 C CA  . HIS E 5 153 ? 365.758 392.536 455.023 1.00 55.10  ? 153 HIS C CA  1 
ATOM 6442 C C   . HIS E 5 153 ? 364.458 392.001 454.454 1.00 55.10  ? 153 HIS C C   1 
ATOM 6443 O O   . HIS E 5 153 ? 364.188 392.110 453.258 1.00 55.10  ? 153 HIS C O   1 
ATOM 6444 C CB  . HIS E 5 153 ? 365.526 393.862 455.742 1.00 55.10  ? 153 HIS C CB  1 
ATOM 6445 C CG  . HIS E 5 153 ? 364.838 394.887 454.901 1.00 55.10  ? 153 HIS C CG  1 
ATOM 6446 N ND1 . HIS E 5 153 ? 363.609 395.412 455.226 1.00 55.10  ? 153 HIS C ND1 1 
ATOM 6447 C CD2 . HIS E 5 153 ? 365.201 395.475 453.739 1.00 55.10  ? 153 HIS C CD2 1 
ATOM 6448 C CE1 . HIS E 5 153 ? 363.248 396.287 454.306 1.00 55.10  ? 153 HIS C CE1 1 
ATOM 6449 N NE2 . HIS E 5 153 ? 364.198 396.346 453.393 1.00 55.10  ? 153 HIS C NE2 1 
ATOM 6450 N N   . VAL E 5 154 ? 363.662 391.391 455.329 1.00 51.07  ? 154 VAL C N   1 
ATOM 6451 C CA  . VAL E 5 154 ? 362.319 390.931 454.996 1.00 51.07  ? 154 VAL C CA  1 
ATOM 6452 C C   . VAL E 5 154 ? 361.374 391.496 456.043 1.00 51.07  ? 154 VAL C C   1 
ATOM 6453 O O   . VAL E 5 154 ? 361.601 391.318 457.242 1.00 51.07  ? 154 VAL C O   1 
ATOM 6454 C CB  . VAL E 5 154 ? 362.198 389.399 454.964 1.00 51.07  ? 154 VAL C CB  1 
ATOM 6455 C CG1 . VAL E 5 154 ? 360.855 389.013 454.421 1.00 51.07  ? 154 VAL C CG1 1 
ATOM 6456 C CG2 . VAL E 5 154 ? 363.284 388.768 454.125 1.00 51.07  ? 154 VAL C CG2 1 
ATOM 6457 N N   . ILE E 5 155 ? 360.324 392.177 455.604 1.00 49.75  ? 155 ILE C N   1 
ATOM 6458 C CA  . ILE E 5 155 ? 359.321 392.688 456.529 1.00 49.75  ? 155 ILE C CA  1 
ATOM 6459 C C   . ILE E 5 155 ? 358.315 391.575 456.774 1.00 49.75  ? 155 ILE C C   1 
ATOM 6460 O O   . ILE E 5 155 ? 357.648 391.112 455.845 1.00 49.75  ? 155 ILE C O   1 
ATOM 6461 C CB  . ILE E 5 155 ? 358.631 393.944 455.981 1.00 49.75  ? 155 ILE C CB  1 
ATOM 6462 C CG1 . ILE E 5 155 ? 359.648 394.997 455.560 1.00 49.75  ? 155 ILE C CG1 1 
ATOM 6463 C CG2 . ILE E 5 155 ? 357.746 394.545 457.029 1.00 49.75  ? 155 ILE C CG2 1 
ATOM 6464 C CD1 . ILE E 5 155 ? 359.818 395.121 454.053 1.00 49.75  ? 155 ILE C CD1 1 
ATOM 6465 N N   . TRP E 5 156 ? 358.201 391.147 458.020 1.00 50.03  ? 156 TRP C N   1 
ATOM 6466 C CA  . TRP E 5 156 ? 357.421 389.972 458.381 1.00 50.03  ? 156 TRP C CA  1 
ATOM 6467 C C   . TRP E 5 156 ? 356.142 390.435 459.057 1.00 50.03  ? 156 TRP C C   1 
ATOM 6468 O O   . TRP E 5 156 ? 356.166 390.843 460.221 1.00 50.03  ? 156 TRP C O   1 
ATOM 6469 C CB  . TRP E 5 156 ? 358.234 389.060 459.294 1.00 50.03  ? 156 TRP C CB  1 
ATOM 6470 C CG  . TRP E 5 156 ? 357.556 387.805 459.704 1.00 50.03  ? 156 TRP C CG  1 
ATOM 6471 C CD1 . TRP E 5 156 ? 356.562 387.158 459.050 1.00 50.03  ? 156 TRP C CD1 1 
ATOM 6472 C CD2 . TRP E 5 156 ? 357.838 387.033 460.870 1.00 50.03  ? 156 TRP C CD2 1 
ATOM 6473 N NE1 . TRP E 5 156 ? 356.199 386.032 459.737 1.00 50.03  ? 156 TRP C NE1 1 
ATOM 6474 C CE2 . TRP E 5 156 ? 356.972 385.935 460.861 1.00 50.03  ? 156 TRP C CE2 1 
ATOM 6475 C CE3 . TRP E 5 156 ? 358.742 387.167 461.923 1.00 50.03  ? 156 TRP C CE3 1 
ATOM 6476 C CZ2 . TRP E 5 156 ? 356.979 384.981 461.860 1.00 50.03  ? 156 TRP C CZ2 1 
ATOM 6477 C CZ3 . TRP E 5 156 ? 358.748 386.223 462.909 1.00 50.03  ? 156 TRP C CZ3 1 
ATOM 6478 C CH2 . TRP E 5 156 ? 357.873 385.144 462.875 1.00 50.03  ? 156 TRP C CH2 1 
ATOM 6479 N N   . ASP E 5 157 ? 355.030 390.374 458.331 1.00 53.71  ? 157 ASP C N   1 
ATOM 6480 C CA  . ASP E 5 157 ? 353.723 390.667 458.897 1.00 53.71  ? 157 ASP C CA  1 
ATOM 6481 C C   . ASP E 5 157 ? 353.177 389.398 459.526 1.00 53.71  ? 157 ASP C C   1 
ATOM 6482 O O   . ASP E 5 157 ? 352.995 388.389 458.842 1.00 53.71  ? 157 ASP C O   1 
ATOM 6483 C CB  . ASP E 5 157 ? 352.760 391.191 457.839 1.00 53.71  ? 157 ASP C CB  1 
ATOM 6484 C CG  . ASP E 5 157 ? 351.647 392.030 458.432 1.00 53.71  ? 157 ASP C CG  1 
ATOM 6485 O OD1 . ASP E 5 157 ? 351.354 391.879 459.634 1.00 53.71  ? 157 ASP C OD1 1 
ATOM 6486 O OD2 . ASP E 5 157 ? 351.063 392.851 457.696 1.00 53.71  ? 157 ASP C OD2 1 
ATOM 6487 N N   . VAL E 5 158 ? 352.904 389.462 460.823 1.00 51.14  ? 158 VAL C N   1 
ATOM 6488 C CA  . VAL E 5 158 ? 352.499 388.282 461.573 1.00 51.14  ? 158 VAL C CA  1 
ATOM 6489 C C   . VAL E 5 158 ? 351.063 387.896 461.247 1.00 51.14  ? 158 VAL C C   1 
ATOM 6490 O O   . VAL E 5 158 ? 350.755 386.715 461.061 1.00 51.14  ? 158 VAL C O   1 
ATOM 6491 C CB  . VAL E 5 158 ? 352.712 388.556 463.070 1.00 51.14  ? 158 VAL C CB  1 
ATOM 6492 C CG1 . VAL E 5 158 ? 351.905 387.634 463.919 1.00 51.14  ? 158 VAL C CG1 1 
ATOM 6493 C CG2 . VAL E 5 158 ? 354.166 388.424 463.403 1.00 51.14  ? 158 VAL C CG2 1 
ATOM 6494 N N   . GLY E 5 159 ? 350.174 388.881 461.114 1.00 54.07  ? 159 GLY C N   1 
ATOM 6495 C CA  . GLY E 5 159 ? 348.764 388.600 460.912 1.00 54.07  ? 159 GLY C CA  1 
ATOM 6496 C C   . GLY E 5 159 ? 348.420 388.000 459.565 1.00 54.07  ? 159 GLY C C   1 
ATOM 6497 O O   . GLY E 5 159 ? 347.307 387.497 459.391 1.00 54.07  ? 159 GLY C O   1 
ATOM 6498 N N   . LEU E 5 160 ? 349.348 388.032 458.613 1.00 57.33  ? 160 LEU C N   1 
ATOM 6499 C CA  . LEU E 5 160 ? 349.105 387.467 457.291 1.00 57.33  ? 160 LEU C CA  1 
ATOM 6500 C C   . LEU E 5 160 ? 349.624 386.038 457.197 1.00 57.33  ? 160 LEU C C   1 
ATOM 6501 O O   . LEU E 5 160 ? 348.912 385.142 456.738 1.00 57.33  ? 160 LEU C O   1 
ATOM 6502 C CB  . LEU E 5 160 ? 349.740 388.344 456.208 1.00 57.33  ? 160 LEU C CB  1 
ATOM 6503 C CG  . LEU E 5 160 ? 348.927 389.525 455.674 1.00 57.33  ? 160 LEU C CG  1 
ATOM 6504 C CD1 . LEU E 5 160 ? 348.795 390.665 456.664 1.00 57.33  ? 160 LEU C CD1 1 
ATOM 6505 C CD2 . LEU E 5 160 ? 349.544 390.024 454.392 1.00 57.33  ? 160 LEU C CD2 1 
ATOM 6506 N N   . GLN E 5 161 ? 350.859 385.812 457.620 1.00 56.51  ? 161 GLN C N   1 
ATOM 6507 C CA  . GLN E 5 161 ? 351.438 384.482 457.644 1.00 56.51  ? 161 GLN C CA  1 
ATOM 6508 C C   . GLN E 5 161 ? 352.224 384.293 458.931 1.00 56.51  ? 161 GLN C C   1 
ATOM 6509 O O   . GLN E 5 161 ? 352.699 385.257 459.531 1.00 56.51  ? 161 GLN C O   1 
ATOM 6510 C CB  . GLN E 5 161 ? 352.338 384.251 456.436 1.00 56.51  ? 161 GLN C CB  1 
ATOM 6511 C CG  . GLN E 5 161 ? 353.489 385.215 456.330 1.00 56.51  ? 161 GLN C CG  1 
ATOM 6512 C CD  . GLN E 5 161 ? 354.296 384.990 455.081 1.00 56.51  ? 161 GLN C CD  1 
ATOM 6513 O OE1 . GLN E 5 161 ? 353.992 384.103 454.287 1.00 56.51  ? 161 GLN C OE1 1 
ATOM 6514 N NE2 . GLN E 5 161 ? 355.337 385.789 454.899 1.00 56.51  ? 161 GLN C NE2 1 
ATOM 6515 N N   . SER E 5 162 ? 352.360 383.040 459.352 1.00 52.66  ? 162 SER C N   1 
ATOM 6516 C CA  . SER E 5 162 ? 352.987 382.721 460.625 1.00 52.66  ? 162 SER C CA  1 
ATOM 6517 C C   . SER E 5 162 ? 354.354 382.071 460.471 1.00 52.66  ? 162 SER C C   1 
ATOM 6518 O O   . SER E 5 162 ? 354.810 381.397 461.397 1.00 52.66  ? 162 SER C O   1 
ATOM 6519 C CB  . SER E 5 162 ? 352.072 381.814 461.443 1.00 52.66  ? 162 SER C CB  1 
ATOM 6520 O OG  . SER E 5 162 ? 350.735 382.277 461.395 1.00 52.66  ? 162 SER C OG  1 
ATOM 6521 N N   . SER E 5 163 ? 355.014 382.252 459.331 1.00 54.26  ? 163 SER C N   1 
ATOM 6522 C CA  . SER E 5 163 ? 356.337 381.688 459.107 1.00 54.26  ? 163 SER C CA  1 
ATOM 6523 C C   . SER E 5 163 ? 357.031 382.469 458.005 1.00 54.26  ? 163 SER C C   1 
ATOM 6524 O O   . SER E 5 163 ? 356.473 382.643 456.921 1.00 54.26  ? 163 SER C O   1 
ATOM 6525 C CB  . SER E 5 163 ? 356.258 380.212 458.719 1.00 54.26  ? 163 SER C CB  1 
ATOM 6526 O OG  . SER E 5 163 ? 356.079 379.403 459.865 1.00 54.26  ? 163 SER C OG  1 
ATOM 6527 N N   . CYS E 5 164 ? 358.247 382.931 458.280 1.00 53.04  ? 164 CYS C N   1 
ATOM 6528 C CA  . CYS E 5 164 ? 359.020 383.670 457.294 1.00 53.04  ? 164 CYS C CA  1 
ATOM 6529 C C   . CYS E 5 164 ? 360.426 383.107 457.226 1.00 53.04  ? 164 CYS C C   1 
ATOM 6530 O O   . CYS E 5 164 ? 361.097 382.980 458.252 1.00 53.04  ? 164 CYS C O   1 
ATOM 6531 C CB  . CYS E 5 164 ? 359.072 385.157 457.619 1.00 53.04  ? 164 CYS C CB  1 
ATOM 6532 S SG  . CYS E 5 164 ? 359.319 386.192 456.168 1.00 53.04  ? 164 CYS C SG  1 
ATOM 6533 N N   . VAL E 5 165 ? 360.871 382.798 456.014 1.00 52.40  ? 165 VAL C N   1 
ATOM 6534 C CA  . VAL E 5 165 ? 362.127 382.110 455.762 1.00 52.40  ? 165 VAL C CA  1 
ATOM 6535 C C   . VAL E 5 165 ? 363.147 383.127 455.273 1.00 52.40  ? 165 VAL C C   1 
ATOM 6536 O O   . VAL E 5 165 ? 362.830 383.988 454.447 1.00 52.40  ? 165 VAL C O   1 
ATOM 6537 C CB  . VAL E 5 165 ? 361.902 380.984 454.734 1.00 52.40  ? 165 VAL C CB  1 
ATOM 6538 C CG1 . VAL E 5 165 ? 363.203 380.345 454.285 1.00 52.40  ? 165 VAL C CG1 1 
ATOM 6539 C CG2 . VAL E 5 165 ? 360.969 379.946 455.304 1.00 52.40  ? 165 VAL C CG2 1 
ATOM 6540 N N   . LEU E 5 166 ? 364.373 383.029 455.784 1.00 53.14  ? 166 LEU C N   1 
ATOM 6541 C CA  . LEU E 5 166 ? 365.464 383.926 455.410 1.00 53.14  ? 166 LEU C CA  1 
ATOM 6542 C C   . LEU E 5 166 ? 366.681 383.067 455.092 1.00 53.14  ? 166 LEU C C   1 
ATOM 6543 O O   . LEU E 5 166 ? 367.340 382.570 456.004 1.00 53.14  ? 166 LEU C O   1 
ATOM 6544 C CB  . LEU E 5 166 ? 365.759 384.901 456.538 1.00 53.14  ? 166 LEU C CB  1 
ATOM 6545 C CG  . LEU E 5 166 ? 366.887 385.912 456.359 1.00 53.14  ? 166 LEU C CG  1 
ATOM 6546 C CD1 . LEU E 5 166 ? 366.577 386.915 455.259 1.00 53.14  ? 166 LEU C CD1 1 
ATOM 6547 C CD2 . LEU E 5 166 ? 367.159 386.612 457.674 1.00 53.14  ? 166 LEU C CD2 1 
ATOM 6548 N N   . CYS E 5 167 ? 366.985 382.899 453.810 1.00 56.27  ? 167 CYS C N   1 
ATOM 6549 C CA  . CYS E 5 167 ? 368.111 382.068 453.406 1.00 56.27  ? 167 CYS C CA  1 
ATOM 6550 C C   . CYS E 5 167 ? 369.413 382.853 453.489 1.00 56.27  ? 167 CYS C C   1 
ATOM 6551 O O   . CYS E 5 167 ? 369.454 384.048 453.193 1.00 56.27  ? 167 CYS C O   1 
ATOM 6552 C CB  . CYS E 5 167 ? 367.905 381.541 451.991 1.00 56.27  ? 167 CYS C CB  1 
ATOM 6553 S SG  . CYS E 5 167 ? 369.104 380.312 451.484 1.00 56.27  ? 167 CYS C SG  1 
ATOM 6554 N N   . VAL E 5 168 ? 370.483 382.172 453.882 1.00 55.22  ? 168 VAL C N   1 
ATOM 6555 C CA  . VAL E 5 168 ? 371.721 382.839 454.281 1.00 55.22  ? 168 VAL C CA  1 
ATOM 6556 C C   . VAL E 5 168 ? 372.920 381.913 454.095 1.00 55.22  ? 168 VAL C C   1 
ATOM 6557 O O   . VAL E 5 168 ? 372.865 380.742 454.493 1.00 55.22  ? 168 VAL C O   1 
ATOM 6558 C CB  . VAL E 5 168 ? 371.597 383.355 455.726 1.00 55.22  ? 168 VAL C CB  1 
ATOM 6559 C CG1 . VAL E 5 168 ? 371.029 382.302 456.637 1.00 55.22  ? 168 VAL C CG1 1 
ATOM 6560 C CG2 . VAL E 5 168 ? 372.930 383.750 456.264 1.00 55.22  ? 168 VAL C CG2 1 
ATOM 6561 N N   . PRO E 5 169 ? 374.000 382.367 453.460 1.00 54.83  ? 169 PRO C N   1 
ATOM 6562 C CA  . PRO E 5 169 ? 375.192 381.522 453.337 1.00 54.83  ? 169 PRO C CA  1 
ATOM 6563 C C   . PRO E 5 169 ? 375.930 381.374 454.657 1.00 54.83  ? 169 PRO C C   1 
ATOM 6564 O O   . PRO E 5 169 ? 375.885 382.245 455.526 1.00 54.83  ? 169 PRO C O   1 
ATOM 6565 C CB  . PRO E 5 169 ? 376.048 382.267 452.312 1.00 54.83  ? 169 PRO C CB  1 
ATOM 6566 C CG  . PRO E 5 169 ? 375.594 383.669 452.403 1.00 54.83  ? 169 PRO C CG  1 
ATOM 6567 C CD  . PRO E 5 169 ? 374.134 383.617 452.702 1.00 54.83  ? 169 PRO C CD  1 
ATOM 6568 N N   . TRP E 5 170 ? 376.619 380.244 454.793 1.00 53.24  ? 170 TRP C N   1 
ATOM 6569 C CA  . TRP E 5 170 ? 377.402 379.929 455.983 1.00 53.24  ? 170 TRP C CA  1 
ATOM 6570 C C   . TRP E 5 170 ? 378.646 379.196 455.517 1.00 53.24  ? 170 TRP C C   1 
ATOM 6571 O O   . TRP E 5 170 ? 378.544 378.250 454.734 1.00 53.24  ? 170 TRP C O   1 
ATOM 6572 C CB  . TRP E 5 170 ? 376.601 379.070 456.953 1.00 53.24  ? 170 TRP C CB  1 
ATOM 6573 C CG  . TRP E 5 170 ? 377.063 379.096 458.370 1.00 53.24  ? 170 TRP C CG  1 
ATOM 6574 C CD1 . TRP E 5 170 ? 377.771 380.077 458.982 1.00 53.24  ? 170 TRP C CD1 1 
ATOM 6575 C CD2 . TRP E 5 170 ? 376.824 378.095 459.365 1.00 53.24  ? 170 TRP C CD2 1 
ATOM 6576 N NE1 . TRP E 5 170 ? 378.001 379.750 460.294 1.00 53.24  ? 170 TRP C NE1 1 
ATOM 6577 C CE2 . TRP E 5 170 ? 377.428 378.536 460.552 1.00 53.24  ? 170 TRP C CE2 1 
ATOM 6578 C CE3 . TRP E 5 170 ? 376.167 376.861 459.361 1.00 53.24  ? 170 TRP C CE3 1 
ATOM 6579 C CZ2 . TRP E 5 170 ? 377.394 377.792 461.724 1.00 53.24  ? 170 TRP C CZ2 1 
ATOM 6580 C CZ3 . TRP E 5 170 ? 376.133 376.125 460.524 1.00 53.24  ? 170 TRP C CZ3 1 
ATOM 6581 C CH2 . TRP E 5 170 ? 376.742 376.590 461.690 1.00 53.24  ? 170 TRP C CH2 1 
ATOM 6582 N N   . ILE E 5 171 ? 379.811 379.627 455.983 1.00 53.64  ? 171 ILE C N   1 
ATOM 6583 C CA  . ILE E 5 171 ? 381.079 379.101 455.506 1.00 53.64  ? 171 ILE C CA  1 
ATOM 6584 C C   . ILE E 5 171 ? 382.045 379.042 456.681 1.00 53.64  ? 171 ILE C C   1 
ATOM 6585 O O   . ILE E 5 171 ? 381.852 379.728 457.689 1.00 53.64  ? 171 ILE C O   1 
ATOM 6586 C CB  . ILE E 5 171 ? 381.622 379.962 454.344 1.00 53.64  ? 171 ILE C CB  1 
ATOM 6587 C CG1 . ILE E 5 171 ? 382.542 379.152 453.434 1.00 53.64  ? 171 ILE C CG1 1 
ATOM 6588 C CG2 . ILE E 5 171 ? 382.324 381.204 454.846 1.00 53.64  ? 171 ILE C CG2 1 
ATOM 6589 C CD1 . ILE E 5 171 ? 382.571 379.657 452.014 1.00 53.64  ? 171 ILE C CD1 1 
ATOM 6590 N N   . SER E 5 172 ? 383.056 378.186 456.574 1.00 52.59  ? 172 SER C N   1 
ATOM 6591 C CA  . SER E 5 172 ? 384.031 378.027 457.641 1.00 52.59  ? 172 SER C CA  1 
ATOM 6592 C C   . SER E 5 172 ? 385.160 379.040 457.520 1.00 52.59  ? 172 SER C C   1 
ATOM 6593 O O   . SER E 5 172 ? 386.063 379.076 458.351 1.00 52.59  ? 172 SER C O   1 
ATOM 6594 C CB  . SER E 5 172 ? 384.602 376.618 457.639 1.00 52.59  ? 172 SER C CB  1 
ATOM 6595 O OG  . SER E 5 172 ? 385.213 376.336 458.880 1.00 52.59  ? 172 SER C OG  1 
ATOM 6596 N N   . ALA E 5 186 ? 384.606 390.048 460.611 1.00 64.70  ? 186 ALA C N   1 
ATOM 6597 C CA  . ALA E 5 186 ? 383.232 389.697 460.938 1.00 64.70  ? 186 ALA C CA  1 
ATOM 6598 C C   . ALA E 5 186 ? 382.771 388.569 460.036 1.00 64.70  ? 186 ALA C C   1 
ATOM 6599 O O   . ALA E 5 186 ? 383.399 388.288 459.020 1.00 64.70  ? 186 ALA C O   1 
ATOM 6600 C CB  . ALA E 5 186 ? 382.322 390.902 460.800 1.00 64.70  ? 186 ALA C CB  1 
ATOM 6601 N N   . ALA E 5 187 ? 381.671 387.918 460.414 1.00 62.64  ? 187 ALA C N   1 
ATOM 6602 C CA  . ALA E 5 187 ? 381.152 386.802 459.640 1.00 62.64  ? 187 ALA C CA  1 
ATOM 6603 C C   . ALA E 5 187 ? 379.651 386.858 459.405 1.00 62.64  ? 187 ALA C C   1 
ATOM 6604 O O   . ALA E 5 187 ? 379.152 386.077 458.592 1.00 62.64  ? 187 ALA C O   1 
ATOM 6605 C CB  . ALA E 5 187 ? 381.504 385.475 460.319 1.00 62.64  ? 187 ALA C CB  1 
ATOM 6606 N N   . GLY E 5 188 ? 378.917 387.736 460.077 1.00 58.60  ? 188 GLY C N   1 
ATOM 6607 C CA  . GLY E 5 188 ? 377.504 387.922 459.818 1.00 58.60  ? 188 GLY C CA  1 
ATOM 6608 C C   . GLY E 5 188 ? 376.703 388.076 461.096 1.00 58.60  ? 188 GLY C C   1 
ATOM 6609 O O   . GLY E 5 188 ? 377.159 387.772 462.195 1.00 58.60  ? 188 GLY C O   1 
ATOM 6610 N N   . TYR E 5 189 ? 375.478 388.569 460.918 1.00 56.06  ? 189 TYR C N   1 
ATOM 6611 C CA  . TYR E 5 189 ? 374.521 388.735 462.002 1.00 56.06  ? 189 TYR C CA  1 
ATOM 6612 C C   . TYR E 5 189 ? 373.117 388.571 461.441 1.00 56.06  ? 189 TYR C C   1 
ATOM 6613 O O   . TYR E 5 189 ? 372.845 388.949 460.301 1.00 56.06  ? 189 TYR C O   1 
ATOM 6614 C CB  . TYR E 5 189 ? 374.636 390.102 462.671 1.00 56.06  ? 189 TYR C CB  1 
ATOM 6615 C CG  . TYR E 5 189 ? 375.826 390.278 463.570 1.00 56.06  ? 189 TYR C CG  1 
ATOM 6616 C CD1 . TYR E 5 189 ? 375.761 389.929 464.906 1.00 56.06  ? 189 TYR C CD1 1 
ATOM 6617 C CD2 . TYR E 5 189 ? 377.003 390.829 463.091 1.00 56.06  ? 189 TYR C CD2 1 
ATOM 6618 C CE1 . TYR E 5 189 ? 376.841 390.101 465.733 1.00 56.06  ? 189 TYR C CE1 1 
ATOM 6619 C CE2 . TYR E 5 189 ? 378.087 391.002 463.907 1.00 56.06  ? 189 TYR C CE2 1 
ATOM 6620 C CZ  . TYR E 5 189 ? 378.001 390.638 465.225 1.00 56.06  ? 189 TYR C CZ  1 
ATOM 6621 O OH  . TYR E 5 189 ? 379.087 390.814 466.043 1.00 56.06  ? 189 TYR C OH  1 
ATOM 6622 N N   . VAL E 5 190 ? 372.225 388.004 462.252 1.00 52.09  ? 190 VAL C N   1 
ATOM 6623 C CA  . VAL E 5 190 ? 370.867 387.692 461.816 1.00 52.09  ? 190 VAL C CA  1 
ATOM 6624 C C   . VAL E 5 190 ? 369.867 388.413 462.718 1.00 52.09  ? 190 VAL C C   1 
ATOM 6625 O O   . VAL E 5 190 ? 368.892 387.814 463.180 1.00 52.09  ? 190 VAL C O   1 
ATOM 6626 C CB  . VAL E 5 190 ? 370.593 386.177 461.788 1.00 52.09  ? 190 VAL C CB  1 
ATOM 6627 C CG1 . VAL E 5 190 ? 369.528 385.854 460.744 1.00 52.09  ? 190 VAL C CG1 1 
ATOM 6628 C CG2 . VAL E 5 190 ? 371.847 385.385 461.514 1.00 52.09  ? 190 VAL C CG2 1 
ATOM 6629 N N   . THR E 5 191 ? 370.158 389.670 463.053 1.00 52.91  ? 191 THR C N   1 
ATOM 6630 C CA  . THR E 5 191 ? 369.346 390.487 463.950 1.00 52.91  ? 191 THR C CA  1 
ATOM 6631 C C   . THR E 5 191 ? 367.896 390.631 463.476 1.00 52.91  ? 191 THR C C   1 
ATOM 6632 O O   . THR E 5 191 ? 367.571 390.426 462.308 1.00 52.91  ? 191 THR C O   1 
ATOM 6633 C CB  . THR E 5 191 ? 369.957 391.874 464.067 1.00 52.91  ? 191 THR C CB  1 
ATOM 6634 O OG1 . THR E 5 191 ? 370.029 392.454 462.764 1.00 52.91  ? 191 THR C OG1 1 
ATOM 6635 C CG2 . THR E 5 191 ? 371.360 391.778 464.608 1.00 52.91  ? 191 THR C CG2 1 
ATOM 6636 N N   . CYS E 5 192 ? 367.021 391.008 464.411 1.00 54.62  ? 192 CYS C N   1 
ATOM 6637 C CA  . CYS E 5 192 ? 365.591 391.152 464.162 1.00 54.62  ? 192 CYS C CA  1 
ATOM 6638 C C   . CYS E 5 192 ? 365.023 392.278 465.010 1.00 54.62  ? 192 CYS C C   1 
ATOM 6639 O O   . CYS E 5 192 ? 365.324 392.369 466.201 1.00 54.62  ? 192 CYS C O   1 
ATOM 6640 C CB  . CYS E 5 192 ? 364.845 389.864 464.473 1.00 54.62  ? 192 CYS C CB  1 
ATOM 6641 S SG  . CYS E 5 192 ? 363.072 390.049 464.727 1.00 54.62  ? 192 CYS C SG  1 
ATOM 6642 N N   . TRP E 5 193 ? 364.171 393.107 464.405 1.00 54.26  ? 193 TRP C N   1 
ATOM 6643 C CA  . TRP E 5 193 ? 363.789 394.392 464.974 1.00 54.26  ? 193 TRP C CA  1 
ATOM 6644 C C   . TRP E 5 193 ? 362.278 394.567 465.013 1.00 54.26  ? 193 TRP C C   1 
ATOM 6645 O O   . TRP E 5 193 ? 361.559 394.095 464.133 1.00 54.26  ? 193 TRP C O   1 
ATOM 6646 C CB  . TRP E 5 193 ? 364.390 395.535 464.171 1.00 54.26  ? 193 TRP C CB  1 
ATOM 6647 C CG  . TRP E 5 193 ? 365.866 395.501 464.122 1.00 54.26  ? 193 TRP C CG  1 
ATOM 6648 C CD1 . TRP E 5 193 ? 366.638 394.814 463.244 1.00 54.26  ? 193 TRP C CD1 1 
ATOM 6649 C CD2 . TRP E 5 193 ? 366.760 396.192 464.989 1.00 54.26  ? 193 TRP C CD2 1 
ATOM 6650 N NE1 . TRP E 5 193 ? 367.960 395.029 463.514 1.00 54.26  ? 193 TRP C NE1 1 
ATOM 6651 C CE2 . TRP E 5 193 ? 368.059 395.873 464.586 1.00 54.26  ? 193 TRP C CE2 1 
ATOM 6652 C CE3 . TRP E 5 193 ? 366.584 397.047 466.074 1.00 54.26  ? 193 TRP C CE3 1 
ATOM 6653 C CZ2 . TRP E 5 193 ? 369.174 396.376 465.224 1.00 54.26  ? 193 TRP C CZ2 1 
ATOM 6654 C CZ3 . TRP E 5 193 ? 367.692 397.545 466.705 1.00 54.26  ? 193 TRP C CZ3 1 
ATOM 6655 C CH2 . TRP E 5 193 ? 368.970 397.212 466.280 1.00 54.26  ? 193 TRP C CH2 1 
ATOM 6656 N N   . TYR E 5 194 ? 361.810 395.263 466.045 1.00 57.61  ? 194 TYR C N   1 
ATOM 6657 C CA  . TYR E 5 194 ? 360.415 395.677 466.127 1.00 57.61  ? 194 TYR C CA  1 
ATOM 6658 C C   . TYR E 5 194 ? 360.133 396.731 465.070 1.00 57.61  ? 194 TYR C C   1 
ATOM 6659 O O   . TYR E 5 194 ? 360.714 397.817 465.107 1.00 57.61  ? 194 TYR C O   1 
ATOM 6660 C CB  . TYR E 5 194 ? 360.113 396.267 467.499 1.00 57.61  ? 194 TYR C CB  1 
ATOM 6661 C CG  . TYR E 5 194 ? 359.753 395.301 468.589 1.00 57.61  ? 194 TYR C CG  1 
ATOM 6662 C CD1 . TYR E 5 194 ? 358.649 394.479 468.481 1.00 57.61  ? 194 TYR C CD1 1 
ATOM 6663 C CD2 . TYR E 5 194 ? 360.501 395.248 469.752 1.00 57.61  ? 194 TYR C CD2 1 
ATOM 6664 C CE1 . TYR E 5 194 ? 358.318 393.610 469.492 1.00 57.61  ? 194 TYR C CE1 1 
ATOM 6665 C CE2 . TYR E 5 194 ? 360.180 394.385 470.763 1.00 57.61  ? 194 TYR C CE2 1 
ATOM 6666 C CZ  . TYR E 5 194 ? 359.091 393.571 470.629 1.00 57.61  ? 194 TYR C CZ  1 
ATOM 6667 O OH  . TYR E 5 194 ? 358.777 392.711 471.647 1.00 57.61  ? 194 TYR C OH  1 
ATOM 6668 N N   . GLN E 5 195 ? 359.226 396.438 464.145 1.00 54.85  ? 195 GLN C N   1 
ATOM 6669 C CA  . GLN E 5 195 ? 358.801 397.466 463.201 1.00 54.85  ? 195 GLN C CA  1 
ATOM 6670 C C   . GLN E 5 195 ? 357.632 398.265 463.766 1.00 54.85  ? 195 GLN C C   1 
ATOM 6671 O O   . GLN E 5 195 ? 357.725 399.484 463.929 1.00 54.85  ? 195 GLN C O   1 
ATOM 6672 C CB  . GLN E 5 195 ? 358.436 396.835 461.858 1.00 54.85  ? 195 GLN C CB  1 
ATOM 6673 C CG  . GLN E 5 195 ? 357.716 397.763 460.921 1.00 54.85  ? 195 GLN C CG  1 
ATOM 6674 C CD  . GLN E 5 195 ? 358.580 398.898 460.463 1.00 54.85  ? 195 GLN C CD  1 
ATOM 6675 O OE1 . GLN E 5 195 ? 359.783 398.744 460.293 1.00 54.85  ? 195 GLN C OE1 1 
ATOM 6676 N NE2 . GLN E 5 195 ? 357.973 400.055 460.256 1.00 54.85  ? 195 GLN C NE2 1 
ATOM 6677 N N   . THR E 5 196 ? 356.531 397.594 464.067 1.00 55.08  ? 196 THR C N   1 
ATOM 6678 C CA  . THR E 5 196 ? 355.421 398.183 464.792 1.00 55.08  ? 196 THR C CA  1 
ATOM 6679 C C   . THR E 5 196 ? 355.259 397.446 466.111 1.00 55.08  ? 196 THR C C   1 
ATOM 6680 O O   . THR E 5 196 ? 355.937 396.456 466.380 1.00 55.08  ? 196 THR C O   1 
ATOM 6681 C CB  . THR E 5 196 ? 354.116 398.112 463.992 1.00 55.08  ? 196 THR C CB  1 
ATOM 6682 O OG1 . THR E 5 196 ? 353.564 396.797 464.101 1.00 55.08  ? 196 THR C OG1 1 
ATOM 6683 C CG2 . THR E 5 196 ? 354.348 398.431 462.536 1.00 55.08  ? 196 THR C CG2 1 
ATOM 6684 N N   . ASN E 5 197 ? 354.346 397.928 466.939 1.00 57.89  ? 197 ASN C N   1 
ATOM 6685 C CA  . ASN E 5 197 ? 354.062 397.219 468.171 1.00 57.89  ? 197 ASN C CA  1 
ATOM 6686 C C   . ASN E 5 197 ? 353.144 396.031 467.906 1.00 57.89  ? 197 ASN C C   1 
ATOM 6687 O O   . ASN E 5 197 ? 352.768 395.736 466.771 1.00 57.89  ? 197 ASN C O   1 
ATOM 6688 C CB  . ASN E 5 197 ? 353.432 398.152 469.196 1.00 57.89  ? 197 ASN C CB  1 
ATOM 6689 C CG  . ASN E 5 197 ? 354.453 398.964 469.932 1.00 57.89  ? 197 ASN C CG  1 
ATOM 6690 O OD1 . ASN E 5 197 ? 355.627 398.963 469.575 1.00 57.89  ? 197 ASN C OD1 1 
ATOM 6691 N ND2 . ASN E 5 197 ? 354.019 399.662 470.971 1.00 57.89  ? 197 ASN C ND2 1 
ATOM 6692 N N   . ILE E 5 198 ? 352.788 395.339 468.981 1.00 57.50  ? 198 ILE C N   1 
ATOM 6693 C CA  . ILE E 5 198 ? 351.860 394.220 468.913 1.00 57.50  ? 198 ILE C CA  1 
ATOM 6694 C C   . ILE E 5 198 ? 350.489 394.749 469.307 1.00 57.50  ? 198 ILE C C   1 
ATOM 6695 O O   . ILE E 5 198 ? 350.306 395.257 470.414 1.00 57.50  ? 198 ILE C O   1 
ATOM 6696 C CB  . ILE E 5 198 ? 352.303 393.068 469.818 1.00 57.50  ? 198 ILE C CB  1 
ATOM 6697 C CG1 . ILE E 5 198 ? 353.523 392.372 469.223 1.00 57.50  ? 198 ILE C CG1 1 
ATOM 6698 C CG2 . ILE E 5 198 ? 351.179 392.075 470.012 1.00 57.50  ? 198 ILE C CG2 1 
ATOM 6699 C CD1 . ILE E 5 198 ? 353.240 391.615 467.949 1.00 57.50  ? 198 ILE C CD1 1 
ATOM 6700 N N   . VAL E 5 199 ? 349.534 394.657 468.397 1.00 56.22  ? 199 VAL C N   1 
ATOM 6701 C CA  . VAL E 5 199 ? 348.181 395.129 468.645 1.00 56.22  ? 199 VAL C CA  1 
ATOM 6702 C C   . VAL E 5 199 ? 347.322 393.929 468.998 1.00 56.22  ? 199 VAL C C   1 
ATOM 6703 O O   . VAL E 5 199 ? 347.283 392.946 468.253 1.00 56.22  ? 199 VAL C O   1 
ATOM 6704 C CB  . VAL E 5 199 ? 347.625 395.872 467.420 1.00 56.22  ? 199 VAL C CB  1 
ATOM 6705 C CG1 . VAL E 5 199 ? 346.161 396.174 467.596 1.00 56.22  ? 199 VAL C CG1 1 
ATOM 6706 C CG2 . VAL E 5 199 ? 348.386 397.155 467.195 1.00 56.22  ? 199 VAL C CG2 1 
ATOM 6707 N N   . VAL E 5 200 ? 346.632 394.005 470.132 1.00 54.65  ? 200 VAL C N   1 
ATOM 6708 C CA  . VAL E 5 200 ? 345.890 392.857 470.649 1.00 54.65  ? 200 VAL C CA  1 
ATOM 6709 C C   . VAL E 5 200 ? 344.523 393.318 471.125 1.00 54.65  ? 200 VAL C C   1 
ATOM 6710 O O   . VAL E 5 200 ? 344.332 394.478 471.513 1.00 54.65  ? 200 VAL C O   1 
ATOM 6711 C CB  . VAL E 5 200 ? 346.668 392.159 471.800 1.00 54.65  ? 200 VAL C CB  1 
ATOM 6712 C CG1 . VAL E 5 200 ? 346.504 392.848 473.162 1.00 54.65  ? 200 VAL C CG1 1 
ATOM 6713 C CG2 . VAL E 5 200 ? 346.374 390.685 471.870 1.00 54.65  ? 200 VAL C CG2 1 
ATOM 6714 N N   . PRO E 5 201 ? 343.516 392.451 470.997 1.00 52.72  ? 201 PRO C N   1 
ATOM 6715 C CA  . PRO E 5 201 ? 342.199 392.785 471.552 1.00 52.72  ? 201 PRO C CA  1 
ATOM 6716 C C   . PRO E 5 201 ? 342.133 392.689 473.063 1.00 52.72  ? 201 PRO C C   1 
ATOM 6717 O O   . PRO E 5 201 ? 343.143 392.453 473.729 1.00 52.72  ? 201 PRO C O   1 
ATOM 6718 C CB  . PRO E 5 201 ? 341.278 391.752 470.901 1.00 52.72  ? 201 PRO C CB  1 
ATOM 6719 C CG  . PRO E 5 201 ? 341.928 391.421 469.658 1.00 52.72  ? 201 PRO C CG  1 
ATOM 6720 C CD  . PRO E 5 201 ? 343.393 391.442 469.937 1.00 52.72  ? 201 PRO C CD  1 
ATOM 6721 N N   . ALA E 5 202 ? 340.945 392.876 473.618 1.00 53.29  ? 202 ALA C N   1 
ATOM 6722 C CA  . ALA E 5 202 ? 340.764 392.715 475.047 1.00 53.29  ? 202 ALA C CA  1 
ATOM 6723 C C   . ALA E 5 202 ? 340.620 391.242 475.387 1.00 53.29  ? 202 ALA C C   1 
ATOM 6724 O O   . ALA E 5 202 ? 340.219 390.434 474.547 1.00 53.29  ? 202 ALA C O   1 
ATOM 6725 C CB  . ALA E 5 202 ? 339.538 393.486 475.525 1.00 53.29  ? 202 ALA C CB  1 
ATOM 6726 N N   . ASP E 5 203 ? 340.975 390.905 476.632 1.00 55.65  ? 203 ASP C N   1 
ATOM 6727 C CA  . ASP E 5 203 ? 340.938 389.544 477.184 1.00 55.65  ? 203 ASP C CA  1 
ATOM 6728 C C   . ASP E 5 203 ? 341.817 388.572 476.399 1.00 55.65  ? 203 ASP C C   1 
ATOM 6729 O O   . ASP E 5 203 ? 341.537 387.375 476.338 1.00 55.65  ? 203 ASP C O   1 
ATOM 6730 C CB  . ASP E 5 203 ? 339.504 389.014 477.294 1.00 55.65  ? 203 ASP C CB  1 
ATOM 6731 C CG  . ASP E 5 203 ? 338.634 389.878 478.183 1.00 55.65  ? 203 ASP C CG  1 
ATOM 6732 O OD1 . ASP E 5 203 ? 339.180 390.485 479.127 1.00 55.65  ? 203 ASP C OD1 1 
ATOM 6733 O OD2 . ASP E 5 203 ? 337.408 389.959 477.943 1.00 55.65  ? 203 ASP C OD2 1 
ATOM 6734 N N   . VAL E 5 204 ? 342.883 389.080 475.783 1.00 52.98  ? 204 VAL C N   1 
ATOM 6735 C CA  . VAL E 5 204 ? 343.896 388.277 475.107 1.00 52.98  ? 204 VAL C CA  1 
ATOM 6736 C C   . VAL E 5 204 ? 345.247 388.713 475.651 1.00 52.98  ? 204 VAL C C   1 
ATOM 6737 O O   . VAL E 5 204 ? 345.511 389.914 475.760 1.00 52.98  ? 204 VAL C O   1 
ATOM 6738 C CB  . VAL E 5 204 ? 343.849 388.448 473.576 1.00 52.98  ? 204 VAL C CB  1 
ATOM 6739 C CG1 . VAL E 5 204 ? 344.806 387.504 472.908 1.00 52.98  ? 204 VAL C CG1 1 
ATOM 6740 C CG2 . VAL E 5 204 ? 342.468 388.206 473.034 1.00 52.98  ? 204 VAL C CG2 1 
ATOM 6741 N N   . GLN E 5 205 ? 346.094 387.748 476.004 1.00 57.04  ? 205 GLN C N   1 
ATOM 6742 C CA  . GLN E 5 205 ? 347.401 388.062 476.562 1.00 57.04  ? 205 GLN C CA  1 
ATOM 6743 C C   . GLN E 5 205 ? 348.335 388.606 475.491 1.00 57.04  ? 205 GLN C C   1 
ATOM 6744 O O   . GLN E 5 205 ? 348.232 388.266 474.312 1.00 57.04  ? 205 GLN C O   1 
ATOM 6745 C CB  . GLN E 5 205 ? 348.020 386.827 477.202 1.00 57.04  ? 205 GLN C CB  1 
ATOM 6746 C CG  . GLN E 5 205 ? 347.662 386.652 478.658 1.00 57.04  ? 205 GLN C CG  1 
ATOM 6747 C CD  . GLN E 5 205 ? 348.457 387.562 479.566 1.00 57.04  ? 205 GLN C CD  1 
ATOM 6748 O OE1 . GLN E 5 205 ? 349.538 388.022 479.210 1.00 57.04  ? 205 GLN C OE1 1 
ATOM 6749 N NE2 . GLN E 5 205 ? 347.923 387.826 480.752 1.00 57.04  ? 205 GLN C NE2 1 
ATOM 6750 N N   . SER E 5 206 ? 349.262 389.459 475.916 1.00 59.58  ? 206 SER C N   1 
ATOM 6751 C CA  . SER E 5 206 ? 350.154 390.145 474.990 1.00 59.58  ? 206 SER C CA  1 
ATOM 6752 C C   . SER E 5 206 ? 351.574 389.607 474.992 1.00 59.58  ? 206 SER C C   1 
ATOM 6753 O O   . SER E 5 206 ? 352.394 390.068 474.196 1.00 59.58  ? 206 SER C O   1 
ATOM 6754 C CB  . SER E 5 206 ? 350.199 391.640 475.303 1.00 59.58  ? 206 SER C CB  1 
ATOM 6755 O OG  . SER E 5 206 ? 350.844 392.339 474.256 1.00 59.58  ? 206 SER C OG  1 
ATOM 6756 N N   . SER E 5 207 ? 351.893 388.663 475.864 1.00 58.61  ? 207 SER C N   1 
ATOM 6757 C CA  . SER E 5 207 ? 353.232 388.091 475.912 1.00 58.61  ? 207 SER C CA  1 
ATOM 6758 C C   . SER E 5 207 ? 353.254 386.813 475.085 1.00 58.61  ? 207 SER C C   1 
ATOM 6759 O O   . SER E 5 207 ? 352.747 385.776 475.520 1.00 58.61  ? 207 SER C O   1 
ATOM 6760 C CB  . SER E 5 207 ? 353.633 387.830 477.357 1.00 58.61  ? 207 SER C CB  1 
ATOM 6761 O OG  . SER E 5 207 ? 353.409 388.983 478.150 1.00 58.61  ? 207 SER C OG  1 
ATOM 6762 N N   . CYS E 5 208 ? 353.842 386.885 473.897 1.00 58.71  ? 208 CYS C N   1 
ATOM 6763 C CA  . CYS E 5 208 ? 353.897 385.785 472.946 1.00 58.71  ? 208 CYS C CA  1 
ATOM 6764 C C   . CYS E 5 208 ? 355.333 385.300 472.802 1.00 58.71  ? 208 CYS C C   1 
ATOM 6765 O O   . CYS E 5 208 ? 356.259 385.885 473.366 1.00 58.71  ? 208 CYS C O   1 
ATOM 6766 C CB  . CYS E 5 208 ? 353.348 386.232 471.591 1.00 58.71  ? 208 CYS C CB  1 
ATOM 6767 S SG  . CYS E 5 208 ? 351.632 386.779 471.636 1.00 58.71  ? 208 CYS C SG  1 
ATOM 6768 N N   . ASP E 5 209 ? 355.519 384.233 472.023 1.00 51.07  ? 209 ASP C N   1 
ATOM 6769 C CA  . ASP E 5 209 ? 356.830 383.623 471.818 1.00 51.07  ? 209 ASP C CA  1 
ATOM 6770 C C   . ASP E 5 209 ? 357.109 383.454 470.329 1.00 51.07  ? 209 ASP C C   1 
ATOM 6771 O O   . ASP E 5 209 ? 356.216 383.569 469.492 1.00 51.07  ? 209 ASP C O   1 
ATOM 6772 C CB  . ASP E 5 209 ? 356.931 382.261 472.513 1.00 51.07  ? 209 ASP C CB  1 
ATOM 6773 C CG  . ASP E 5 209 ? 357.176 382.369 474.004 1.00 51.07  ? 209 ASP C CG  1 
ATOM 6774 O OD1 . ASP E 5 209 ? 357.137 383.478 474.558 1.00 51.07  ? 209 ASP C OD1 1 
ATOM 6775 O OD2 . ASP E 5 209 ? 357.411 381.323 474.634 1.00 51.07  ? 209 ASP C OD2 1 
ATOM 6776 N N   . ILE E 5 210 ? 358.368 383.165 470.005 1.00 48.00  ? 210 ILE C N   1 
ATOM 6777 C CA  . ILE E 5 210 ? 358.825 382.938 468.634 1.00 48.00  ? 210 ILE C CA  1 
ATOM 6778 C C   . ILE E 5 210 ? 359.832 381.795 468.661 1.00 48.00  ? 210 ILE C C   1 
ATOM 6779 O O   . ILE E 5 210 ? 360.775 381.822 469.455 1.00 48.00  ? 210 ILE C O   1 
ATOM 6780 C CB  . ILE E 5 210 ? 359.471 384.202 468.024 1.00 48.00  ? 210 ILE C CB  1 
ATOM 6781 C CG1 . ILE E 5 210 ? 358.422 385.215 467.587 1.00 48.00  ? 210 ILE C CG1 1 
ATOM 6782 C CG2 . ILE E 5 210 ? 360.349 383.877 466.827 1.00 48.00  ? 210 ILE C CG2 1 
ATOM 6783 C CD1 . ILE E 5 210 ? 359.021 386.496 467.085 1.00 48.00  ? 210 ILE C CD1 1 
ATOM 6784 N N   . LEU E 5 211 ? 359.637 380.794 467.808 1.00 46.93  ? 211 LEU C N   1 
ATOM 6785 C CA  . LEU E 5 211 ? 360.587 379.704 467.652 1.00 46.93  ? 211 LEU C CA  1 
ATOM 6786 C C   . LEU E 5 211 ? 361.381 379.873 466.363 1.00 46.93  ? 211 LEU C C   1 
ATOM 6787 O O   . LEU E 5 211 ? 361.016 380.655 465.488 1.00 46.93  ? 211 LEU C O   1 
ATOM 6788 C CB  . LEU E 5 211 ? 359.868 378.359 467.640 1.00 46.93  ? 211 LEU C CB  1 
ATOM 6789 C CG  . LEU E 5 211 ? 359.154 377.911 468.905 1.00 46.93  ? 211 LEU C CG  1 
ATOM 6790 C CD1 . LEU E 5 211 ? 358.291 376.735 468.557 1.00 46.93  ? 211 LEU C CD1 1 
ATOM 6791 C CD2 . LEU E 5 211 ? 360.148 377.528 469.965 1.00 46.93  ? 211 LEU C CD2 1 
ATOM 6792 N N   . CYS E 5 212 ? 362.469 379.114 466.243 1.00 49.01  ? 212 CYS C N   1 
ATOM 6793 C CA  . CYS E 5 212 ? 363.381 379.253 465.115 1.00 49.01  ? 212 CYS C CA  1 
ATOM 6794 C C   . CYS E 5 212 ? 363.974 377.910 464.725 1.00 49.01  ? 212 CYS C C   1 
ATOM 6795 O O   . CYS E 5 212 ? 364.648 377.271 465.533 1.00 49.01  ? 212 CYS C O   1 
ATOM 6796 C CB  . CYS E 5 212 ? 364.513 380.230 465.445 1.00 49.01  ? 212 CYS C CB  1 
ATOM 6797 S SG  . CYS E 5 212 ? 365.741 380.438 464.144 1.00 49.01  ? 212 CYS C SG  1 
ATOM 6798 N N   . PHE E 5 213 ? 363.752 377.501 463.480 1.00 47.94  ? 213 PHE C N   1 
ATOM 6799 C CA  . PHE E 5 213 ? 364.277 376.247 462.963 1.00 47.94  ? 213 PHE C CA  1 
ATOM 6800 C C   . PHE E 5 213 ? 365.424 376.519 462.004 1.00 47.94  ? 213 PHE C C   1 
ATOM 6801 O O   . PHE E 5 213 ? 365.526 377.601 461.425 1.00 47.94  ? 213 PHE C O   1 
ATOM 6802 C CB  . PHE E 5 213 ? 363.199 375.435 462.245 1.00 47.94  ? 213 PHE C CB  1 
ATOM 6803 C CG  . PHE E 5 213 ? 361.897 375.381 462.974 1.00 47.94  ? 213 PHE C CG  1 
ATOM 6804 C CD1 . PHE E 5 213 ? 361.748 374.593 464.091 1.00 47.94  ? 213 PHE C CD1 1 
ATOM 6805 C CD2 . PHE E 5 213 ? 360.817 376.110 462.531 1.00 47.94  ? 213 PHE C CD2 1 
ATOM 6806 C CE1 . PHE E 5 213 ? 360.556 374.549 464.761 1.00 47.94  ? 213 PHE C CE1 1 
ATOM 6807 C CE2 . PHE E 5 213 ? 359.623 376.063 463.200 1.00 47.94  ? 213 PHE C CE2 1 
ATOM 6808 C CZ  . PHE E 5 213 ? 359.496 375.284 464.314 1.00 47.94  ? 213 PHE C CZ  1 
ATOM 6809 N N   . VAL E 5 214 ? 366.288 375.522 461.827 1.00 50.46  ? 214 VAL C N   1 
ATOM 6810 C CA  . VAL E 5 214 ? 367.447 375.647 460.953 1.00 50.46  ? 214 VAL C CA  1 
ATOM 6811 C C   . VAL E 5 214 ? 367.553 374.380 460.113 1.00 50.46  ? 214 VAL C C   1 
ATOM 6812 O O   . VAL E 5 214 ? 367.124 373.299 460.528 1.00 50.46  ? 214 VAL C O   1 
ATOM 6813 C CB  . VAL E 5 214 ? 368.738 375.915 461.768 1.00 50.46  ? 214 VAL C CB  1 
ATOM 6814 C CG1 . VAL E 5 214 ? 369.178 374.698 462.554 1.00 50.46  ? 214 VAL C CG1 1 
ATOM 6815 C CG2 . VAL E 5 214 ? 369.851 376.429 460.904 1.00 50.46  ? 214 VAL C CG2 1 
ATOM 6816 N N   . SER E 5 215 ? 368.076 374.525 458.901 1.00 56.31  ? 215 SER C N   1 
ATOM 6817 C CA  . SER E 5 215 ? 368.242 373.401 457.993 1.00 56.31  ? 215 SER C CA  1 
ATOM 6818 C C   . SER E 5 215 ? 369.342 373.750 457.000 1.00 56.31  ? 215 SER C C   1 
ATOM 6819 O O   . SER E 5 215 ? 369.959 374.816 457.095 1.00 56.31  ? 215 SER C O   1 
ATOM 6820 C CB  . SER E 5 215 ? 366.919 373.078 457.286 1.00 56.31  ? 215 SER C CB  1 
ATOM 6821 O OG  . SER E 5 215 ? 367.097 372.045 456.341 1.00 56.31  ? 215 SER C OG  1 
ATOM 6822 N N   . ALA E 5 216 ? 369.580 372.864 456.043 1.00 59.66  ? 216 ALA C N   1 
ATOM 6823 C CA  . ALA E 5 216 ? 370.501 373.126 454.948 1.00 59.66  ? 216 ALA C CA  1 
ATOM 6824 C C   . ALA E 5 216 ? 369.686 373.215 453.673 1.00 59.66  ? 216 ALA C C   1 
ATOM 6825 O O   . ALA E 5 216 ? 368.930 372.293 453.359 1.00 59.66  ? 216 ALA C O   1 
ATOM 6826 C CB  . ALA E 5 216 ? 371.557 372.032 454.842 1.00 59.66  ? 216 ALA C CB  1 
ATOM 6827 N N   . CYS E 5 217 ? 369.821 374.321 452.946 1.00 64.81  ? 217 CYS C N   1 
ATOM 6828 C CA  . CYS E 5 217 ? 368.971 374.534 451.782 1.00 64.81  ? 217 CYS C CA  1 
ATOM 6829 C C   . CYS E 5 217 ? 369.447 373.706 450.600 1.00 64.81  ? 217 CYS C C   1 
ATOM 6830 O O   . CYS E 5 217 ? 368.742 372.804 450.141 1.00 64.81  ? 217 CYS C O   1 
ATOM 6831 C CB  . CYS E 5 217 ? 368.932 376.012 451.407 1.00 64.81  ? 217 CYS C CB  1 
ATOM 6832 S SG  . CYS E 5 217 ? 368.224 376.349 449.786 1.00 64.81  ? 217 CYS C SG  1 
ATOM 6833 N N   . ASN E 5 218 ? 370.643 373.992 450.111 1.00 69.15  ? 218 ASN C N   1 
ATOM 6834 C CA  . ASN E 5 218 ? 371.217 373.212 449.030 1.00 69.15  ? 218 ASN C CA  1 
ATOM 6835 C C   . ASN E 5 218 ? 372.068 372.098 449.629 1.00 69.15  ? 218 ASN C C   1 
ATOM 6836 O O   . ASN E 5 218 ? 372.088 371.888 450.843 1.00 69.15  ? 218 ASN C O   1 
ATOM 6837 C CB  . ASN E 5 218 ? 372.026 374.109 448.098 1.00 69.15  ? 218 ASN C CB  1 
ATOM 6838 C CG  . ASN E 5 218 ? 371.164 374.820 447.082 1.00 69.15  ? 218 ASN C CG  1 
ATOM 6839 O OD1 . ASN E 5 218 ? 370.461 374.188 446.298 1.00 69.15  ? 218 ASN C OD1 1 
ATOM 6840 N ND2 . ASN E 5 218 ? 371.220 376.145 447.084 1.00 69.15  ? 218 ASN C ND2 1 
ATOM 6841 N N   . ASP E 5 219 ? 372.781 371.369 448.784 1.00 69.85  ? 219 ASP C N   1 
ATOM 6842 C CA  . ASP E 5 219 ? 373.715 370.369 449.272 1.00 69.85  ? 219 ASP C CA  1 
ATOM 6843 C C   . ASP E 5 219 ? 374.976 371.073 449.752 1.00 69.85  ? 219 ASP C C   1 
ATOM 6844 O O   . ASP E 5 219 ? 375.448 372.016 449.110 1.00 69.85  ? 219 ASP C O   1 
ATOM 6845 C CB  . ASP E 5 219 ? 374.038 369.363 448.167 1.00 69.85  ? 219 ASP C CB  1 
ATOM 6846 C CG  . ASP E 5 219 ? 374.453 368.007 448.707 1.00 69.85  ? 219 ASP C CG  1 
ATOM 6847 O OD1 . ASP E 5 219 ? 375.073 367.954 449.789 1.00 69.85  ? 219 ASP C OD1 1 
ATOM 6848 O OD2 . ASP E 5 219 ? 374.162 366.990 448.044 1.00 69.85  ? 219 ASP C OD2 1 
ATOM 6849 N N   . PHE E 5 220 ? 375.518 370.629 450.880 1.00 61.96  ? 220 PHE C N   1 
ATOM 6850 C CA  . PHE E 5 220 ? 376.766 371.199 451.370 1.00 61.96  ? 220 PHE C CA  1 
ATOM 6851 C C   . PHE E 5 220 ? 377.951 370.599 450.622 1.00 61.96  ? 220 PHE C C   1 
ATOM 6852 O O   . PHE E 5 220 ? 377.815 369.895 449.619 1.00 61.96  ? 220 PHE C O   1 
ATOM 6853 C CB  . PHE E 5 220 ? 376.935 370.990 452.869 1.00 61.96  ? 220 PHE C CB  1 
ATOM 6854 C CG  . PHE E 5 220 ? 376.450 372.131 453.697 1.00 61.96  ? 220 PHE C CG  1 
ATOM 6855 C CD1 . PHE E 5 220 ? 375.392 372.906 453.281 1.00 61.96  ? 220 PHE C CD1 1 
ATOM 6856 C CD2 . PHE E 5 220 ? 377.124 372.490 454.848 1.00 61.96  ? 220 PHE C CD2 1 
ATOM 6857 C CE1 . PHE E 5 220 ? 374.967 373.967 454.041 1.00 61.96  ? 220 PHE C CE1 1 
ATOM 6858 C CE2 . PHE E 5 220 ? 376.707 373.559 455.603 1.00 61.96  ? 220 PHE C CE2 1 
ATOM 6859 C CZ  . PHE E 5 220 ? 375.629 374.300 455.197 1.00 61.96  ? 220 PHE C CZ  1 
ATOM 6860 N N   . SER E 5 221 ? 379.145 370.883 451.123 1.00 62.33  ? 221 SER C N   1 
ATOM 6861 C CA  . SER E 5 221 ? 380.375 370.335 450.566 1.00 62.33  ? 221 SER C CA  1 
ATOM 6862 C C   . SER E 5 221 ? 381.326 370.144 451.737 1.00 62.33  ? 221 SER C C   1 
ATOM 6863 O O   . SER E 5 221 ? 381.951 371.103 452.185 1.00 62.33  ? 221 SER C O   1 
ATOM 6864 C CB  . SER E 5 221 ? 380.965 371.259 449.513 1.00 62.33  ? 221 SER C CB  1 
ATOM 6865 O OG  . SER E 5 221 ? 381.896 370.581 448.691 1.00 62.33  ? 221 SER C OG  1 
ATOM 6866 N N   . VAL E 5 222 ? 381.434 368.921 452.219 1.00 60.34  ? 222 VAL C N   1 
ATOM 6867 C CA  . VAL E 5 222 ? 382.251 368.607 453.381 1.00 60.34  ? 222 VAL C CA  1 
ATOM 6868 C C   . VAL E 5 222 ? 383.488 367.845 452.940 1.00 60.34  ? 222 VAL C C   1 
ATOM 6869 O O   . VAL E 5 222 ? 383.436 366.995 452.047 1.00 60.34  ? 222 VAL C O   1 
ATOM 6870 C CB  . VAL E 5 222 ? 381.439 367.805 454.411 1.00 60.34  ? 222 VAL C CB  1 
ATOM 6871 C CG1 . VAL E 5 222 ? 380.524 368.727 455.166 1.00 60.34  ? 222 VAL C CG1 1 
ATOM 6872 C CG2 . VAL E 5 222 ? 380.624 366.751 453.707 1.00 60.34  ? 222 VAL C CG2 1 
ATOM 6873 N N   . ARG E 5 223 ? 384.621 368.167 453.560 1.00 60.09  ? 223 ARG C N   1 
ATOM 6874 C CA  . ARG E 5 223 ? 385.885 367.510 453.256 1.00 60.09  ? 223 ARG C CA  1 
ATOM 6875 C C   . ARG E 5 223 ? 386.667 367.315 454.546 1.00 60.09  ? 223 ARG C C   1 
ATOM 6876 O O   . ARG E 5 223 ? 386.464 368.039 455.521 1.00 60.09  ? 223 ARG C O   1 
ATOM 6877 C CB  . ARG E 5 223 ? 386.715 368.320 452.254 1.00 60.09  ? 223 ARG C CB  1 
ATOM 6878 C CG  . ARG E 5 223 ? 386.160 368.361 450.846 1.00 60.09  ? 223 ARG C CG  1 
ATOM 6879 C CD  . ARG E 5 223 ? 386.504 369.650 450.149 1.00 60.09  ? 223 ARG C CD  1 
ATOM 6880 N NE  . ARG E 5 223 ? 387.944 369.827 450.033 1.00 60.09  ? 223 ARG C NE  1 
ATOM 6881 C CZ  . ARG E 5 223 ? 388.697 369.250 449.106 1.00 60.09  ? 223 ARG C CZ  1 
ATOM 6882 N NH1 . ARG E 5 223 ? 388.150 368.457 448.197 1.00 60.09  ? 223 ARG C NH1 1 
ATOM 6883 N NH2 . ARG E 5 223 ? 390.001 369.472 449.083 1.00 60.09  ? 223 ARG C NH2 1 
ATOM 6884 N N   . MET E 5 224 ? 387.572 366.328 454.523 1.00 57.85  ? 224 MET C N   1 
ATOM 6885 C CA  . MET E 5 224 ? 388.552 366.052 455.582 1.00 57.85  ? 224 MET C CA  1 
ATOM 6886 C C   . MET E 5 224 ? 387.871 365.738 456.921 1.00 57.85  ? 224 MET C C   1 
ATOM 6887 O O   . MET E 5 224 ? 387.821 366.558 457.836 1.00 57.85  ? 224 MET C O   1 
ATOM 6888 C CB  . MET E 5 224 ? 389.560 367.201 455.715 1.00 57.85  ? 224 MET C CB  1 
ATOM 6889 C CG  . MET E 5 224 ? 390.793 366.880 456.554 1.00 57.85  ? 224 MET C CG  1 
ATOM 6890 S SD  . MET E 5 224 ? 391.674 365.417 455.993 1.00 57.85  ? 224 MET C SD  1 
ATOM 6891 C CE  . MET E 5 224 ? 392.111 365.903 454.332 1.00 57.85  ? 224 MET C CE  1 
ATOM 6892 N N   . LEU E 5 225 ? 387.272 364.549 456.968 1.00 51.98  ? 225 LEU C N   1 
ATOM 6893 C CA  . LEU E 5 225 ? 386.625 364.062 458.183 1.00 51.98  ? 225 LEU C CA  1 
ATOM 6894 C C   . LEU E 5 225 ? 387.607 363.943 459.345 1.00 51.98  ? 225 LEU C C   1 
ATOM 6895 O O   . LEU E 5 225 ? 388.744 363.502 459.180 1.00 51.98  ? 225 LEU C O   1 
ATOM 6896 C CB  . LEU E 5 225 ? 385.974 362.705 457.916 1.00 51.98  ? 225 LEU C CB  1 
ATOM 6897 C CG  . LEU E 5 225 ? 385.201 362.005 459.032 1.00 51.98  ? 225 LEU C CG  1 
ATOM 6898 C CD1 . LEU E 5 225 ? 383.876 361.545 458.520 1.00 51.98  ? 225 LEU C CD1 1 
ATOM 6899 C CD2 . LEU E 5 225 ? 385.968 360.825 459.546 1.00 51.98  ? 225 LEU C CD2 1 
ATOM 6900 N N   . LYS E 5 226 ? 387.152 364.342 460.528 1.00 53.95  ? 226 LYS C N   1 
ATOM 6901 C CA  . LYS E 5 226 ? 387.934 364.265 461.751 1.00 53.95  ? 226 LYS C CA  1 
ATOM 6902 C C   . LYS E 5 226 ? 387.002 363.826 462.871 1.00 53.95  ? 226 LYS C C   1 
ATOM 6903 O O   . LYS E 5 226 ? 385.891 363.352 462.626 1.00 53.95  ? 226 LYS C O   1 
ATOM 6904 C CB  . LYS E 5 226 ? 388.604 365.607 462.057 1.00 53.95  ? 226 LYS C CB  1 
ATOM 6905 C CG  . LYS E 5 226 ? 387.636 366.757 462.236 1.00 53.95  ? 226 LYS C CG  1 
ATOM 6906 C CD  . LYS E 5 226 ? 388.237 367.833 463.105 1.00 53.95  ? 226 LYS C CD  1 
ATOM 6907 C CE  . LYS E 5 226 ? 387.263 368.961 463.309 1.00 53.95  ? 226 LYS C CE  1 
ATOM 6908 N NZ  . LYS E 5 226 ? 385.927 368.439 463.656 1.00 53.95  ? 226 LYS C NZ  1 
ATOM 6909 N N   . ASP E 5 227 ? 387.446 363.973 464.110 1.00 59.67  ? 227 ASP C N   1 
ATOM 6910 C CA  . ASP E 5 227 ? 386.625 363.601 465.249 1.00 59.67  ? 227 ASP C CA  1 
ATOM 6911 C C   . ASP E 5 227 ? 386.059 364.839 465.927 1.00 59.67  ? 227 ASP C C   1 
ATOM 6912 O O   . ASP E 5 227 ? 386.612 365.935 465.841 1.00 59.67  ? 227 ASP C O   1 
ATOM 6913 C CB  . ASP E 5 227 ? 387.425 362.783 466.256 1.00 59.67  ? 227 ASP C CB  1 
ATOM 6914 C CG  . ASP E 5 227 ? 388.372 363.629 467.059 1.00 59.67  ? 227 ASP C CG  1 
ATOM 6915 O OD1 . ASP E 5 227 ? 389.130 364.407 466.446 1.00 59.67  ? 227 ASP C OD1 1 
ATOM 6916 O OD2 . ASP E 5 227 ? 388.357 363.526 468.303 1.00 59.67  ? 227 ASP C OD2 1 
ATOM 6917 N N   . THR E 5 228 ? 384.951 364.646 466.603 1.00 57.85  ? 228 THR C N   1 
ATOM 6918 C CA  . THR E 5 228 ? 384.225 365.709 467.270 1.00 57.85  ? 228 THR C CA  1 
ATOM 6919 C C   . THR E 5 228 ? 384.860 366.034 468.622 1.00 57.85  ? 228 THR C C   1 
ATOM 6920 O O   . THR E 5 228 ? 385.468 365.169 469.255 1.00 57.85  ? 228 THR C O   1 
ATOM 6921 C CB  . THR E 5 228 ? 382.772 365.293 467.454 1.00 57.85  ? 228 THR C CB  1 
ATOM 6922 O OG1 . THR E 5 228 ? 382.108 366.199 468.339 1.00 57.85  ? 228 THR C OG1 1 
ATOM 6923 C CG2 . THR E 5 228 ? 382.689 363.896 468.003 1.00 57.85  ? 228 THR C CG2 1 
ATOM 6924 N N   . PRO E 5 229 ? 384.768 367.286 469.075 1.00 56.99  ? 229 PRO C N   1 
ATOM 6925 C CA  . PRO E 5 229 ? 385.250 367.619 470.418 1.00 56.99  ? 229 PRO C CA  1 
ATOM 6926 C C   . PRO E 5 229 ? 384.218 367.438 471.513 1.00 56.99  ? 229 PRO C C   1 
ATOM 6927 O O   . PRO E 5 229 ? 384.541 367.659 472.683 1.00 56.99  ? 229 PRO C O   1 
ATOM 6928 C CB  . PRO E 5 229 ? 385.625 369.094 470.277 1.00 56.99  ? 229 PRO C CB  1 
ATOM 6929 C CG  . PRO E 5 229 ? 384.666 369.602 469.291 1.00 56.99  ? 229 PRO C CG  1 
ATOM 6930 C CD  . PRO E 5 229 ? 384.457 368.498 468.300 1.00 56.99  ? 229 PRO C CD  1 
ATOM 6931 N N   . PHE E 5 230 ? 382.998 367.037 471.182 1.00 57.25  ? 230 PHE C N   1 
ATOM 6932 C CA  . PHE E 5 230 ? 381.903 367.046 472.135 1.00 57.25  ? 230 PHE C CA  1 
ATOM 6933 C C   . PHE E 5 230 ? 381.849 365.810 473.014 1.00 57.25  ? 230 PHE C C   1 
ATOM 6934 O O   . PHE E 5 230 ? 381.086 365.795 473.981 1.00 57.25  ? 230 PHE C O   1 
ATOM 6935 C CB  . PHE E 5 230 ? 380.577 367.199 471.399 1.00 57.25  ? 230 PHE C CB  1 
ATOM 6936 C CG  . PHE E 5 230 ? 380.384 368.546 470.785 1.00 57.25  ? 230 PHE C CG  1 
ATOM 6937 C CD1 . PHE E 5 230 ? 380.839 369.683 471.428 1.00 57.25  ? 230 PHE C CD1 1 
ATOM 6938 C CD2 . PHE E 5 230 ? 379.749 368.677 469.567 1.00 57.25  ? 230 PHE C CD2 1 
ATOM 6939 C CE1 . PHE E 5 230 ? 380.663 370.926 470.866 1.00 57.25  ? 230 PHE C CE1 1 
ATOM 6940 C CE2 . PHE E 5 230 ? 379.568 369.914 469.000 1.00 57.25  ? 230 PHE C CE2 1 
ATOM 6941 C CZ  . PHE E 5 230 ? 380.028 371.040 469.649 1.00 57.25  ? 230 PHE C CZ  1 
ATOM 6942 N N   . ILE E 5 231 ? 382.632 364.779 472.721 1.00 57.43  ? 231 ILE C N   1 
ATOM 6943 C CA  . ILE E 5 231 ? 382.588 363.544 473.492 1.00 57.43  ? 231 ILE C CA  1 
ATOM 6944 C C   . ILE E 5 231 ? 384.014 363.101 473.792 1.00 57.43  ? 231 ILE C C   1 
ATOM 6945 O O   . ILE E 5 231 ? 384.886 363.126 472.917 1.00 57.43  ? 231 ILE C O   1 
ATOM 6946 C CB  . ILE E 5 231 ? 381.773 362.462 472.751 1.00 57.43  ? 231 ILE C CB  1 
ATOM 6947 C CG1 . ILE E 5 231 ? 381.761 361.154 473.530 1.00 57.43  ? 231 ILE C CG1 1 
ATOM 6948 C CG2 . ILE E 5 231 ? 382.250 362.273 471.336 1.00 57.43  ? 231 ILE C CG2 1 
ATOM 6949 C CD1 . ILE E 5 231 ? 380.975 361.234 474.808 1.00 57.43  ? 231 ILE C CD1 1 
ATOM 6950 N N   . ARG E 5 232 ? 384.270 362.744 475.044 1.00 61.59  ? 232 ARG C N   1 
ATOM 6951 C CA  . ARG E 5 232 ? 385.617 362.359 475.431 1.00 61.59  ? 232 ARG C CA  1 
ATOM 6952 C C   . ARG E 5 232 ? 385.528 361.301 476.517 1.00 61.59  ? 232 ARG C C   1 
ATOM 6953 O O   . ARG E 5 232 ? 384.442 360.943 476.974 1.00 61.59  ? 232 ARG C O   1 
ATOM 6954 C CB  . ARG E 5 232 ? 386.425 363.568 475.889 1.00 61.59  ? 232 ARG C CB  1 
ATOM 6955 C CG  . ARG E 5 232 ? 385.885 364.245 477.119 1.00 61.59  ? 232 ARG C CG  1 
ATOM 6956 C CD  . ARG E 5 232 ? 386.932 365.175 477.686 1.00 61.59  ? 232 ARG C CD  1 
ATOM 6957 N NE  . ARG E 5 232 ? 388.265 364.592 477.568 1.00 61.59  ? 232 ARG C NE  1 
ATOM 6958 C CZ  . ARG E 5 232 ? 388.817 363.799 478.478 1.00 61.59  ? 232 ARG C CZ  1 
ATOM 6959 N NH1 . ARG E 5 232 ? 390.032 363.312 478.278 1.00 61.59  ? 232 ARG C NH1 1 
ATOM 6960 N NH2 . ARG E 5 232 ? 388.157 363.498 479.588 1.00 61.59  ? 232 ARG C NH2 1 
ATOM 6961 N N   . GLN E 5 233 ? 386.690 360.808 476.933 1.00 61.50  ? 233 GLN C N   1 
ATOM 6962 C CA  . GLN E 5 233 ? 386.751 359.602 477.742 1.00 61.50  ? 233 GLN C CA  1 
ATOM 6963 C C   . GLN E 5 233 ? 388.079 359.525 478.475 1.00 61.50  ? 233 GLN C C   1 
ATOM 6964 O O   . GLN E 5 233 ? 389.121 359.853 477.902 1.00 61.50  ? 233 GLN C O   1 
ATOM 6965 C CB  . GLN E 5 233 ? 386.571 358.374 476.848 1.00 61.50  ? 233 GLN C CB  1 
ATOM 6966 C CG  . GLN E 5 233 ? 386.534 357.054 477.560 1.00 61.50  ? 233 GLN C CG  1 
ATOM 6967 C CD  . GLN E 5 233 ? 386.530 355.898 476.599 1.00 61.50  ? 233 GLN C CD  1 
ATOM 6968 O OE1 . GLN E 5 233 ? 387.104 355.981 475.520 1.00 61.50  ? 233 GLN C OE1 1 
ATOM 6969 N NE2 . GLN E 5 233 ? 385.876 354.815 476.978 1.00 61.50  ? 233 GLN C NE2 1 
ATOM 6970 N N   . ASP E 5 234 ? 388.042 359.094 479.736 1.00 67.10  ? 234 ASP C N   1 
ATOM 6971 C CA  . ASP E 5 234 ? 389.255 358.772 480.476 1.00 67.10  ? 234 ASP C CA  1 
ATOM 6972 C C   . ASP E 5 234 ? 389.422 357.282 480.718 1.00 67.10  ? 234 ASP C C   1 
ATOM 6973 O O   . ASP E 5 234 ? 390.510 356.750 480.489 1.00 67.10  ? 234 ASP C O   1 
ATOM 6974 C CB  . ASP E 5 234 ? 389.266 359.481 481.829 1.00 67.10  ? 234 ASP C CB  1 
ATOM 6975 C CG  . ASP E 5 234 ? 388.812 360.904 481.734 1.00 67.10  ? 234 ASP C CG  1 
ATOM 6976 O OD1 . ASP E 5 234 ? 389.475 361.693 481.034 1.00 67.10  ? 234 ASP C OD1 1 
ATOM 6977 O OD2 . ASP E 5 234 ? 387.784 361.238 482.358 1.00 67.10  ? 234 ASP C OD2 1 
ATOM 6978 N N   . THR E 5 235 ? 388.377 356.605 481.182 1.00 66.30  ? 235 THR C N   1 
ATOM 6979 C CA  . THR E 5 235 ? 388.437 355.196 481.531 1.00 66.30  ? 235 THR C CA  1 
ATOM 6980 C C   . THR E 5 235 ? 387.468 354.448 480.634 1.00 66.30  ? 235 THR C C   1 
ATOM 6981 O O   . THR E 5 235 ? 386.520 355.044 480.129 1.00 66.30  ? 235 THR C O   1 
ATOM 6982 C CB  . THR E 5 235 ? 388.043 354.970 482.990 1.00 66.30  ? 235 THR C CB  1 
ATOM 6983 O OG1 . THR E 5 235 ? 386.619 354.891 483.066 1.00 66.30  ? 235 THR C OG1 1 
ATOM 6984 C CG2 . THR E 5 235 ? 388.506 356.120 483.870 1.00 66.30  ? 235 THR C CG2 1 
ATOM 6985 N N   . PHE E 5 236 ? 387.700 353.152 480.447 1.00 63.91  ? 236 PHE C N   1 
ATOM 6986 C CA  . PHE E 5 236 ? 386.783 352.341 479.658 1.00 63.91  ? 236 PHE C CA  1 
ATOM 6987 C C   . PHE E 5 236 ? 385.445 352.191 480.362 1.00 63.91  ? 236 PHE C C   1 
ATOM 6988 O O   . PHE E 5 236 ? 385.386 352.033 481.582 1.00 63.91  ? 236 PHE C O   1 
ATOM 6989 C CB  . PHE E 5 236 ? 387.379 350.961 479.400 1.00 63.91  ? 236 PHE C CB  1 
ATOM 6990 C CG  . PHE E 5 236 ? 388.426 350.934 478.333 1.00 63.91  ? 236 PHE C CG  1 
ATOM 6991 C CD1 . PHE E 5 236 ? 388.579 351.996 477.461 1.00 63.91  ? 236 PHE C CD1 1 
ATOM 6992 C CD2 . PHE E 5 236 ? 389.241 349.824 478.186 1.00 63.91  ? 236 PHE C CD2 1 
ATOM 6993 C CE1 . PHE E 5 236 ? 389.537 351.964 476.472 1.00 63.91  ? 236 PHE C CE1 1 
ATOM 6994 C CE2 . PHE E 5 236 ? 390.202 349.784 477.203 1.00 63.91  ? 236 PHE C CE2 1 
ATOM 6995 C CZ  . PHE E 5 236 ? 390.350 350.855 476.343 1.00 63.91  ? 236 PHE C CZ  1 
ATOM 6996 N N   . TYR E 5 237 ? 384.367 352.247 479.588 1.00 59.44  ? 237 TYR C N   1 
ATOM 6997 C CA  . TYR E 5 237 ? 383.057 351.940 480.137 1.00 59.44  ? 237 TYR C CA  1 
ATOM 6998 C C   . TYR E 5 237 ? 382.944 350.438 480.318 1.00 59.44  ? 237 TYR C C   1 
ATOM 6999 O O   . TYR E 5 237 ? 383.249 349.667 479.408 1.00 59.44  ? 237 TYR C O   1 
ATOM 7000 C CB  . TYR E 5 237 ? 381.945 352.431 479.217 1.00 59.44  ? 237 TYR C CB  1 
ATOM 7001 C CG  . TYR E 5 237 ? 382.086 353.853 478.743 1.00 59.44  ? 237 TYR C CG  1 
ATOM 7002 C CD1 . TYR E 5 237 ? 382.425 354.863 479.619 1.00 59.44  ? 237 TYR C CD1 1 
ATOM 7003 C CD2 . TYR E 5 237 ? 381.870 354.185 477.417 1.00 59.44  ? 237 TYR C CD2 1 
ATOM 7004 C CE1 . TYR E 5 237 ? 382.553 356.160 479.192 1.00 59.44  ? 237 TYR C CE1 1 
ATOM 7005 C CE2 . TYR E 5 237 ? 381.999 355.482 476.982 1.00 59.44  ? 237 TYR C CE2 1 
ATOM 7006 C CZ  . TYR E 5 237 ? 382.342 356.464 477.878 1.00 59.44  ? 237 TYR C CZ  1 
ATOM 7007 O OH  . TYR E 5 237 ? 382.470 357.766 477.469 1.00 59.44  ? 237 TYR C OH  1 
ATOM 7008 N N   . GLN E 5 238 ? 382.530 350.019 481.505 1.00 69.16  ? 238 GLN C N   1 
ATOM 7009 C CA  . GLN E 5 238 ? 382.486 348.599 481.841 1.00 69.16  ? 238 GLN C CA  1 
ATOM 7010 C C   . GLN E 5 238 ? 381.241 348.252 482.644 1.00 69.16  ? 238 GLN C C   1 
ATOM 7011 O O   . GLN E 5 238 ? 381.040 348.766 483.741 1.00 69.16  ? 238 GLN C O   1 
ATOM 7012 C CB  . GLN E 5 238 ? 383.744 348.198 482.618 1.00 69.16  ? 238 GLN C CB  1 
ATOM 7013 C CG  . GLN E 5 238 ? 385.000 348.107 481.767 1.00 69.16  ? 238 GLN C CG  1 
ATOM 7014 C CD  . GLN E 5 238 ? 386.246 347.947 482.587 1.00 69.16  ? 238 GLN C CD  1 
ATOM 7015 O OE1 . GLN E 5 238 ? 386.201 348.013 483.810 1.00 69.16  ? 238 GLN C OE1 1 
ATOM 7016 N NE2 . GLN E 5 238 ? 387.375 347.742 481.920 1.00 69.16  ? 238 GLN C NE2 1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   1   1   ASP ASP L . n 
A 1 2   ILE 2   2   2   ILE ILE L . n 
A 1 3   GLN 3   3   3   GLN GLN L . n 
A 1 4   MET 4   4   4   MET MET L . n 
A 1 5   THR 5   5   5   THR THR L . n 
A 1 6   GLN 6   6   6   GLN GLN L . n 
A 1 7   THR 7   7   7   THR THR L . n 
A 1 8   LYS 8   8   8   LYS LYS L . n 
A 1 9   SER 9   9   9   SER SER L . n 
A 1 10  SER 10  10  10  SER SER L . n 
A 1 11  LEU 11  11  11  LEU LEU L . n 
A 1 12  SER 12  12  12  SER SER L . n 
A 1 13  ALA 13  13  13  ALA ALA L . n 
A 1 14  SER 14  14  14  SER SER L . n 
A 1 15  LEU 15  15  15  LEU LEU L . n 
A 1 16  GLY 16  16  16  GLY GLY L . n 
A 1 17  ASP 17  17  17  ASP ASP L . n 
A 1 18  ARG 18  18  18  ARG ARG L . n 
A 1 19  VAL 19  19  19  VAL VAL L . n 
A 1 20  THR 20  20  20  THR THR L . n 
A 1 21  ILE 21  21  21  ILE ILE L . n 
A 1 22  SER 22  22  22  SER SER L . n 
A 1 23  CYS 23  23  23  CYS CYS L . n 
A 1 24  ARG 24  24  24  ARG ARG L . n 
A 1 25  ALA 25  25  25  ALA ALA L . n 
A 1 26  SER 26  26  26  SER SER L . n 
A 1 27  GLN 27  27  27  GLN GLN L . n 
A 1 28  ASP 28  28  28  ASP ASP L . n 
A 1 29  ILE 29  29  29  ILE ILE L . n 
A 1 30  SER 30  30  30  SER SER L . n 
A 1 31  ASN 31  31  31  ASN ASN L . n 
A 1 32  TYR 32  32  32  TYR TYR L . n 
A 1 33  LEU 33  33  33  LEU LEU L . n 
A 1 34  ASN 34  34  34  ASN ASN L . n 
A 1 35  TRP 35  35  35  TRP TRP L . n 
A 1 36  TYR 36  36  36  TYR TYR L . n 
A 1 37  GLN 37  37  37  GLN GLN L . n 
A 1 38  GLN 38  38  38  GLN GLN L . n 
A 1 39  LYS 39  39  39  LYS LYS L . n 
A 1 40  PRO 40  40  40  PRO PRO L . n 
A 1 41  ASP 41  41  41  ASP ASP L . n 
A 1 42  GLY 42  42  42  GLY GLY L . n 
A 1 43  SER 43  43  43  SER SER L . n 
A 1 44  VAL 44  44  44  VAL VAL L . n 
A 1 45  LYS 45  45  45  LYS LYS L . n 
A 1 46  LEU 46  46  46  LEU LEU L . n 
A 1 47  LEU 47  47  47  LEU LEU L . n 
A 1 48  ILE 48  48  48  ILE ILE L . n 
A 1 49  TYR 49  49  49  TYR TYR L . n 
A 1 50  TYR 50  50  50  TYR TYR L . n 
A 1 51  THR 51  51  51  THR THR L . n 
A 1 52  SER 52  52  52  SER SER L . n 
A 1 53  THR 53  53  53  THR THR L . n 
A 1 54  LEU 54  54  54  LEU LEU L . n 
A 1 55  HIS 55  55  55  HIS HIS L . n 
A 1 56  SER 56  56  56  SER SER L . n 
A 1 57  GLY 57  57  57  GLY GLY L . n 
A 1 58  VAL 58  58  58  VAL VAL L . n 
A 1 59  PRO 59  59  59  PRO PRO L . n 
A 1 60  SER 60  60  60  SER SER L . n 
A 1 61  ARG 61  61  61  ARG ARG L . n 
A 1 62  PHE 62  62  62  PHE PHE L . n 
A 1 63  SER 63  63  63  SER SER L . n 
A 1 64  GLY 64  64  64  GLY GLY L . n 
A 1 65  SER 65  65  65  SER SER L . n 
A 1 66  GLY 66  66  66  GLY GLY L . n 
A 1 67  SER 67  67  67  SER SER L . n 
A 1 68  GLY 68  68  68  GLY GLY L . n 
A 1 69  THR 69  69  69  THR THR L . n 
A 1 70  ASP 70  70  70  ASP ASP L . n 
A 1 71  TYR 71  71  71  TYR TYR L . n 
A 1 72  SER 72  72  72  SER SER L . n 
A 1 73  LEU 73  73  73  LEU LEU L . n 
A 1 74  THR 74  74  74  THR THR L . n 
A 1 75  ILE 75  75  75  ILE ILE L . n 
A 1 76  ASN 76  76  76  ASN ASN L . n 
A 1 77  SER 77  77  77  SER SER L . n 
A 1 78  LEU 78  78  78  LEU LEU L . n 
A 1 79  GLU 79  79  79  GLU GLU L . n 
A 1 80  GLN 80  80  80  GLN GLN L . n 
A 1 81  GLU 81  81  81  GLU GLU L . n 
A 1 82  ASP 82  82  82  ASP ASP L . n 
A 1 83  ILE 83  83  83  ILE ILE L . n 
A 1 84  ALA 84  84  84  ALA ALA L . n 
A 1 85  THR 85  85  85  THR THR L . n 
A 1 86  TYR 86  86  86  TYR TYR L . n 
A 1 87  PHE 87  87  87  PHE PHE L . n 
A 1 88  CYS 88  88  88  CYS CYS L . n 
A 1 89  GLN 89  89  89  GLN GLN L . n 
A 1 90  GLN 90  90  90  GLN GLN L . n 
A 1 91  GLY 91  91  91  GLY GLY L . n 
A 1 92  ASN 92  92  92  ASN ASN L . n 
A 1 93  THR 93  93  93  THR THR L . n 
A 1 94  PHE 94  94  94  PHE PHE L . n 
A 1 95  PRO 95  95  95  PRO PRO L . n 
A 1 96  PHE 96  96  96  PHE PHE L . n 
A 1 97  THR 97  97  97  THR THR L . n 
A 1 98  PHE 98  98  98  PHE PHE L . n 
A 1 99  GLY 99  99  99  GLY GLY L . n 
A 1 100 GLY 100 100 100 GLY GLY L . n 
A 1 101 GLY 101 101 101 GLY GLY L . n 
A 1 102 THR 102 102 102 THR THR L . n 
A 1 103 LYS 103 103 103 LYS LYS L . n 
A 1 104 LEU 104 104 104 LEU LEU L . n 
A 1 105 GLU 105 105 105 GLU GLU L . n 
A 1 106 ILE 106 106 106 ILE ILE L . n 
A 1 107 ARG 107 107 107 ARG ARG L . n 
A 1 108 ARG 108 108 108 ARG ARG L . n 
B 2 1   GLN 1   1   ?   ?   ?   H . n 
B 2 2   VAL 2   2   2   VAL VAL H . n 
B 2 3   GLN 3   3   3   GLN GLN H . n 
B 2 4   LEU 4   4   4   LEU LEU H . n 
B 2 5   GLN 5   5   5   GLN GLN H . n 
B 2 6   GLN 6   6   6   GLN GLN H . n 
B 2 7   SER 7   7   7   SER SER H . n 
B 2 8   ALA 8   8   8   ALA ALA H . n 
B 2 9   ALA 9   9   9   ALA ALA H . n 
B 2 10  GLU 10  10  10  GLU GLU H . n 
B 2 11  LEU 11  11  11  LEU LEU H . n 
B 2 12  ALA 12  12  12  ALA ALA H . n 
B 2 13  ARG 13  13  13  ARG ARG H . n 
B 2 14  PRO 14  14  14  PRO PRO H . n 
B 2 15  GLY 15  15  15  GLY GLY H . n 
B 2 16  ALA 16  16  16  ALA ALA H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  VAL 18  18  18  VAL VAL H . n 
B 2 19  LYS 19  19  19  LYS LYS H . n 
B 2 20  MET 20  20  20  MET MET H . n 
B 2 21  SER 21  21  21  SER SER H . n 
B 2 22  CYS 22  22  22  CYS CYS H . n 
B 2 23  LYS 23  23  23  LYS LYS H . n 
B 2 24  ALA 24  24  24  ALA ALA H . n 
B 2 25  SER 25  25  25  SER SER H . n 
B 2 26  GLY 26  26  26  GLY GLY H . n 
B 2 27  TYR 27  27  27  TYR TYR H . n 
B 2 28  THR 28  28  28  THR THR H . n 
B 2 29  PHE 29  29  29  PHE PHE H . n 
B 2 30  THR 30  30  30  THR THR H . n 
B 2 31  THR 31  31  31  THR THR H . n 
B 2 32  TYR 32  32  32  TYR TYR H . n 
B 2 33  THR 33  33  33  THR THR H . n 
B 2 34  MET 34  34  34  MET MET H . n 
B 2 35  HIS 35  35  35  HIS HIS H . n 
B 2 36  TRP 36  36  36  TRP TRP H . n 
B 2 37  VAL 37  37  37  VAL VAL H . n 
B 2 38  LYS 38  38  38  LYS LYS H . n 
B 2 39  GLN 39  39  39  GLN GLN H . n 
B 2 40  ARG 40  40  40  ARG ARG H . n 
B 2 41  PRO 41  41  41  PRO PRO H . n 
B 2 42  GLY 42  42  42  GLY GLY H . n 
B 2 43  GLN 43  43  43  GLN GLN H . n 
B 2 44  GLY 44  44  44  GLY GLY H . n 
B 2 45  LEU 45  45  45  LEU LEU H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  TRP 47  47  47  TRP TRP H . n 
B 2 48  ILE 48  48  48  ILE ILE H . n 
B 2 49  GLY 49  49  49  GLY GLY H . n 
B 2 50  TYR 50  50  50  TYR TYR H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  ASN 52  52  52  ASN ASN H . n 
B 2 53  PRO 53  53  53  PRO PRO H . n 
B 2 54  SER 54  54  54  SER SER H . n 
B 2 55  SER 55  55  55  SER SER H . n 
B 2 56  ARG 56  56  56  ARG ARG H . n 
B 2 57  TYR 57  57  57  TYR TYR H . n 
B 2 58  THR 58  58  58  THR THR H . n 
B 2 59  GLU 59  59  59  GLU GLU H . n 
B 2 60  TYR 60  60  60  TYR TYR H . n 
B 2 61  ASN 61  61  61  ASN ASN H . n 
B 2 62  GLN 62  62  62  GLN GLN H . n 
B 2 63  LYS 63  63  63  LYS LYS H . n 
B 2 64  PHE 64  64  64  PHE PHE H . n 
B 2 65  LYS 65  65  65  LYS LYS H . n 
B 2 66  ASP 66  66  66  ASP ASP H . n 
B 2 67  LYS 67  67  67  LYS LYS H . n 
B 2 68  THR 68  68  68  THR THR H . n 
B 2 69  THR 69  69  69  THR THR H . n 
B 2 70  LEU 70  70  70  LEU LEU H . n 
B 2 71  THR 71  71  71  THR THR H . n 
B 2 72  ALA 72  72  72  ALA ALA H . n 
B 2 73  ASP 73  73  73  ASP ASP H . n 
B 2 74  LYS 74  74  74  LYS LYS H . n 
B 2 75  SER 75  75  75  SER SER H . n 
B 2 76  SER 76  76  76  SER SER H . n 
B 2 77  SER 77  77  77  SER SER H . n 
B 2 78  THR 78  78  78  THR THR H . n 
B 2 79  ALA 79  79  79  ALA ALA H . n 
B 2 80  TYR 80  80  80  TYR TYR H . n 
B 2 81  MET 81  81  81  MET MET H . n 
B 2 82  GLN 82  82  82  GLN GLN H . n 
B 2 83  LEU 83  83  83  LEU LEU H . n 
B 2 84  SER 84  84  84  SER SER H . n 
B 2 85  SER 85  85  85  SER SER H . n 
B 2 86  LEU 86  86  86  LEU LEU H . n 
B 2 87  THR 87  87  87  THR THR H . n 
B 2 88  PHE 88  88  88  PHE PHE H . n 
B 2 89  GLU 89  89  89  GLU GLU H . n 
B 2 90  ASP 90  90  90  ASP ASP H . n 
B 2 91  SER 91  91  91  SER SER H . n 
B 2 92  ALA 92  92  92  ALA ALA H . n 
B 2 93  VAL 93  93  93  VAL VAL H . n 
B 2 94  TYR 94  94  94  TYR TYR H . n 
B 2 95  TYR 95  95  95  TYR TYR H . n 
B 2 96  CYS 96  96  96  CYS CYS H . n 
B 2 97  ALA 97  97  97  ALA ALA H . n 
B 2 98  ARG 98  98  98  ARG ARG H . n 
B 2 99  ARG 99  99  99  ARG ARG H . n 
B 2 100 SER 100 100 100 SER SER H . n 
B 2 101 GLU 101 101 101 GLU GLU H . n 
B 2 102 ALA 102 102 102 ALA ALA H . n 
B 2 103 ASP 103 103 103 ASP ASP H . n 
B 2 104 ARG 104 104 104 ARG ARG H . n 
B 2 105 PHE 105 105 105 PHE PHE H . n 
B 2 106 VAL 106 106 106 VAL VAL H . n 
B 2 107 TYR 107 107 107 TYR TYR H . n 
B 2 108 TRP 108 108 108 TRP TRP H . n 
B 2 109 GLY 109 109 109 GLY GLY H . n 
B 2 110 GLN 110 110 110 GLN GLN H . n 
B 2 111 GLY 111 111 111 GLY GLY H . n 
B 2 112 THR 112 112 112 THR THR H . n 
B 2 113 LEU 113 113 113 LEU LEU H . n 
B 2 114 VAL 114 114 114 VAL VAL H . n 
B 2 115 THR 115 115 115 THR THR H . n 
B 2 116 VAL 116 116 116 VAL VAL H . n 
B 2 117 SER 117 117 117 SER SER H . n 
B 2 118 ALA 118 118 118 ALA ALA H . n 
C 3 1   GLY 1   1   ?   ?   ?   A . n 
C 3 2   PRO 2   2   ?   ?   ?   A . n 
C 3 3   VAL 3   3   ?   ?   ?   A . n 
C 3 4   GLU 4   4   ?   ?   ?   A . n 
C 3 5   GLU 5   5   ?   ?   ?   A . n 
C 3 6   SER 6   6   ?   ?   ?   A . n 
C 3 7   VAL 7   7   ?   ?   ?   A . n 
C 3 8   ASP 8   8   ?   ?   ?   A . n 
C 3 9   ARG 9   9   ?   ?   ?   A . n 
C 3 10  ALA 10  10  ?   ?   ?   A . n 
C 3 11  VAL 11  11  ?   ?   ?   A . n 
C 3 12  ALA 12  12  ?   ?   ?   A . n 
C 3 13  ARG 13  13  ?   ?   ?   A . n 
C 3 14  VAL 14  14  ?   ?   ?   A . n 
C 3 15  ALA 15  15  ?   ?   ?   A . n 
C 3 16  ASP 16  16  ?   ?   ?   A . n 
C 3 17  THR 17  17  ?   ?   ?   A . n 
C 3 18  ILE 18  18  ?   ?   ?   A . n 
C 3 19  SER 19  19  ?   ?   ?   A . n 
C 3 20  SER 20  20  ?   ?   ?   A . n 
C 3 21  ARG 21  21  ?   ?   ?   A . n 
C 3 22  PRO 22  22  ?   ?   ?   A . n 
C 3 23  THR 23  23  ?   ?   ?   A . n 
C 3 24  ASN 24  24  ?   ?   ?   A . n 
C 3 25  SER 25  25  ?   ?   ?   A . n 
C 3 26  GLU 26  26  ?   ?   ?   A . n 
C 3 27  SER 27  27  ?   ?   ?   A . n 
C 3 28  ILE 28  28  ?   ?   ?   A . n 
C 3 29  PRO 29  29  ?   ?   ?   A . n 
C 3 30  ALA 30  30  ?   ?   ?   A . n 
C 3 31  LEU 31  31  ?   ?   ?   A . n 
C 3 32  THR 32  32  ?   ?   ?   A . n 
C 3 33  ALA 33  33  ?   ?   ?   A . n 
C 3 34  ALA 34  34  ?   ?   ?   A . n 
C 3 35  GLU 35  35  ?   ?   ?   A . n 
C 3 36  THR 36  36  ?   ?   ?   A . n 
C 3 37  GLY 37  37  ?   ?   ?   A . n 
C 3 38  HIS 38  38  ?   ?   ?   A . n 
C 3 39  THR 39  39  ?   ?   ?   A . n 
C 3 40  SER 40  40  ?   ?   ?   A . n 
C 3 41  GLN 41  41  ?   ?   ?   A . n 
C 3 42  VAL 42  42  ?   ?   ?   A . n 
C 3 43  VAL 43  43  ?   ?   ?   A . n 
C 3 44  PRO 44  44  ?   ?   ?   A . n 
C 3 45  SER 45  45  ?   ?   ?   A . n 
C 3 46  ASP 46  46  ?   ?   ?   A . n 
C 3 47  THR 47  47  ?   ?   ?   A . n 
C 3 48  MET 48  48  ?   ?   ?   A . n 
C 3 49  GLN 49  49  ?   ?   ?   A . n 
C 3 50  THR 50  50  ?   ?   ?   A . n 
C 3 51  ARG 51  51  ?   ?   ?   A . n 
C 3 52  HIS 52  52  ?   ?   ?   A . n 
C 3 53  VAL 53  53  ?   ?   ?   A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ASN 55  55  ?   ?   ?   A . n 
C 3 56  TYR 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  SER 58  58  58  SER SER A . n 
C 3 59  ARG 59  59  59  ARG ARG A . n 
C 3 60  SER 60  60  60  SER SER A . n 
C 3 61  GLU 61  61  61  GLU GLU A . n 
C 3 62  SER 62  62  62  SER SER A . n 
C 3 63  SER 63  63  63  SER SER A . n 
C 3 64  ILE 64  64  64  ILE ILE A . n 
C 3 65  GLU 65  65  65  GLU GLU A . n 
C 3 66  ASN 66  66  66  ASN ASN A . n 
C 3 67  PHE 67  67  67  PHE PHE A . n 
C 3 68  LEU 68  68  68  LEU LEU A . n 
C 3 69  CYS 69  69  69  CYS CYS A . n 
C 3 70  ARG 70  70  70  ARG ARG A . n 
C 3 71  SER 71  71  71  SER SER A . n 
C 3 72  ALA 72  72  72  ALA ALA A . n 
C 3 73  CYS 73  73  73  CYS CYS A . n 
C 3 74  VAL 74  74  74  VAL VAL A . n 
C 3 75  TYR 75  75  75  TYR TYR A . n 
C 3 76  TYR 76  76  76  TYR TYR A . n 
C 3 77  ALA 77  77  77  ALA ALA A . n 
C 3 78  THR 78  78  78  THR THR A . n 
C 3 79  TYR 79  79  79  TYR TYR A . n 
C 3 80  THR 80  80  80  THR THR A . n 
C 3 81  ASN 81  81  81  ASN ASN A . n 
C 3 82  ASN 82  82  82  ASN ASN A . n 
C 3 83  SER 83  83  83  SER SER A . n 
C 3 84  LYS 84  84  84  LYS LYS A . n 
C 3 85  LYS 85  85  85  LYS LYS A . n 
C 3 86  GLY 86  86  86  GLY GLY A . n 
C 3 87  PHE 87  87  87  PHE PHE A . n 
C 3 88  ALA 88  88  88  ALA ALA A . n 
C 3 89  GLU 89  89  89  GLU GLU A . n 
C 3 90  TRP 90  90  90  TRP TRP A . n 
C 3 91  VAL 91  91  91  VAL VAL A . n 
C 3 92  ILE 92  92  92  ILE ILE A . n 
C 3 93  ASN 93  93  93  ASN ASN A . n 
C 3 94  THR 94  94  94  THR THR A . n 
C 3 95  ARG 95  95  95  ARG ARG A . n 
C 3 96  GLN 96  96  96  GLN GLN A . n 
C 3 97  VAL 97  97  97  VAL VAL A . n 
C 3 98  ALA 98  98  98  ALA ALA A . n 
C 3 99  GLN 99  99  99  GLN GLN A . n 
C 3 100 LEU 100 100 100 LEU LEU A . n 
C 3 101 ARG 101 101 101 ARG ARG A . n 
C 3 102 ARG 102 102 102 ARG ARG A . n 
C 3 103 LYS 103 103 103 LYS LYS A . n 
C 3 104 LEU 104 104 104 LEU LEU A . n 
C 3 105 GLU 105 105 105 GLU GLU A . n 
C 3 106 LEU 106 106 106 LEU LEU A . n 
C 3 107 PHE 107 107 107 PHE PHE A . n 
C 3 108 THR 108 108 108 THR THR A . n 
C 3 109 TYR 109 109 109 TYR TYR A . n 
C 3 110 LEU 110 110 110 LEU LEU A . n 
C 3 111 ARG 111 111 111 ARG ARG A . n 
C 3 112 PHE 112 112 112 PHE PHE A . n 
C 3 113 ASP 113 113 113 ASP ASP A . n 
C 3 114 LEU 114 114 114 LEU LEU A . n 
C 3 115 GLU 115 115 115 GLU GLU A . n 
C 3 116 LEU 116 116 116 LEU LEU A . n 
C 3 117 THR 117 117 117 THR THR A . n 
C 3 118 PHE 118 118 118 PHE PHE A . n 
C 3 119 VAL 119 119 119 VAL VAL A . n 
C 3 120 ILE 120 120 120 ILE ILE A . n 
C 3 121 THR 121 121 121 THR THR A . n 
C 3 122 SER 122 122 122 SER SER A . n 
C 3 123 ALA 123 123 123 ALA ALA A . n 
C 3 124 GLN 124 124 124 GLN GLN A . n 
C 3 125 GLN 125 125 125 GLN GLN A . n 
C 3 126 PRO 126 126 126 PRO PRO A . n 
C 3 127 SER 127 127 127 SER SER A . n 
C 3 128 THR 128 128 128 THR THR A . n 
C 3 129 ALA 129 129 129 ALA ALA A . n 
C 3 130 SER 130 130 130 SER SER A . n 
C 3 131 SER 131 131 131 SER SER A . n 
C 3 132 VAL 132 132 132 VAL VAL A . n 
C 3 133 ASP 133 133 133 ASP ASP A . n 
C 3 134 ALA 134 134 134 ALA ALA A . n 
C 3 135 PRO 135 135 135 PRO PRO A . n 
C 3 136 VAL 136 136 136 VAL VAL A . n 
C 3 137 GLN 137 137 137 GLN GLN A . n 
C 3 138 THR 138 138 138 THR THR A . n 
C 3 139 HIS 139 139 139 HIS HIS A . n 
C 3 140 GLN 140 140 140 GLN GLN A . n 
C 3 141 ILE 141 141 141 ILE ILE A . n 
C 3 142 MET 142 142 142 MET MET A . n 
C 3 143 TYR 143 143 143 TYR TYR A . n 
C 3 144 VAL 144 144 144 VAL VAL A . n 
C 3 145 PRO 145 145 145 PRO PRO A . n 
C 3 146 PRO 146 146 146 PRO PRO A . n 
C 3 147 GLY 147 147 147 GLY GLY A . n 
C 3 148 GLY 148 148 148 GLY GLY A . n 
C 3 149 PRO 149 149 149 PRO PRO A . n 
C 3 150 VAL 150 150 150 VAL VAL A . n 
C 3 151 PRO 151 151 151 PRO PRO A . n 
C 3 152 THR 152 152 152 THR THR A . n 
C 3 153 LYS 153 153 153 LYS LYS A . n 
C 3 154 VAL 154 154 154 VAL VAL A . n 
C 3 155 LYS 155 155 155 LYS LYS A . n 
C 3 156 ASP 156 156 156 ASP ASP A . n 
C 3 157 TYR 157 157 157 TYR TYR A . n 
C 3 158 ALA 158 158 158 ALA ALA A . n 
C 3 159 TRP 159 159 159 TRP TRP A . n 
C 3 160 GLN 160 160 160 GLN GLN A . n 
C 3 161 THR 161 161 161 THR THR A . n 
C 3 162 SER 162 162 162 SER SER A . n 
C 3 163 THR 163 163 163 THR THR A . n 
C 3 164 ASN 164 164 164 ASN ASN A . n 
C 3 165 PRO 165 165 165 PRO PRO A . n 
C 3 166 SER 166 166 166 SER SER A . n 
C 3 167 VAL 167 167 167 VAL VAL A . n 
C 3 168 PHE 168 168 168 PHE PHE A . n 
C 3 169 TRP 169 169 169 TRP TRP A . n 
C 3 170 THR 170 170 170 THR THR A . n 
C 3 171 GLU 171 171 171 GLU GLU A . n 
C 3 172 GLY 172 172 172 GLY GLY A . n 
C 3 173 ASN 173 173 173 ASN ASN A . n 
C 3 174 ALA 174 174 174 ALA ALA A . n 
C 3 175 PRO 175 175 175 PRO PRO A . n 
C 3 176 PRO 176 176 176 PRO PRO A . n 
C 3 177 ARG 177 177 177 ARG ARG A . n 
C 3 178 MET 178 178 178 MET MET A . n 
C 3 179 SER 179 179 179 SER SER A . n 
C 3 180 ILE 180 180 180 ILE ILE A . n 
C 3 181 PRO 181 181 181 PRO PRO A . n 
C 3 182 PHE 182 182 182 PHE PHE A . n 
C 3 183 ILE 183 183 183 ILE ILE A . n 
C 3 184 SER 184 184 184 SER SER A . n 
C 3 185 ILE 185 185 185 ILE ILE A . n 
C 3 186 GLY 186 186 186 GLY GLY A . n 
C 3 187 ASN 187 187 187 ASN ASN A . n 
C 3 188 ALA 188 188 188 ALA ALA A . n 
C 3 189 TYR 189 189 189 TYR TYR A . n 
C 3 190 SER 190 190 190 SER SER A . n 
C 3 191 CYS 191 191 191 CYS CYS A . n 
C 3 192 PHE 192 192 192 PHE PHE A . n 
C 3 193 TYR 193 193 193 TYR TYR A . n 
C 3 194 ASP 194 194 194 ASP ASP A . n 
C 3 195 GLY 195 195 195 GLY GLY A . n 
C 3 196 TRP 196 196 196 TRP TRP A . n 
C 3 197 THR 197 197 197 THR THR A . n 
C 3 198 GLN 198 198 ?   ?   ?   A . n 
C 3 199 PHE 199 199 ?   ?   ?   A . n 
C 3 200 SER 200 200 ?   ?   ?   A . n 
C 3 201 ARG 201 201 ?   ?   ?   A . n 
C 3 202 ASN 202 202 ?   ?   ?   A . n 
C 3 203 GLY 203 203 ?   ?   ?   A . n 
C 3 204 VAL 204 204 204 VAL VAL A . n 
C 3 205 TYR 205 205 205 TYR TYR A . n 
C 3 206 GLY 206 206 206 GLY GLY A . n 
C 3 207 ILE 207 207 207 ILE ILE A . n 
C 3 208 ASN 208 208 208 ASN ASN A . n 
C 3 209 THR 209 209 209 THR THR A . n 
C 3 210 LEU 210 210 210 LEU LEU A . n 
C 3 211 ASN 211 211 211 ASN ASN A . n 
C 3 212 ASN 212 212 212 ASN ASN A . n 
C 3 213 MET 213 213 213 MET MET A . n 
C 3 214 GLY 214 214 214 GLY GLY A . n 
C 3 215 THR 215 215 215 THR THR A . n 
C 3 216 LEU 216 216 216 LEU LEU A . n 
C 3 217 TYR 217 217 217 TYR TYR A . n 
C 3 218 MET 218 218 218 MET MET A . n 
C 3 219 ARG 219 219 219 ARG ARG A . n 
C 3 220 HIS 220 220 220 HIS HIS A . n 
C 3 221 VAL 221 221 221 VAL VAL A . n 
C 3 222 ASN 222 222 222 ASN ASN A . n 
C 3 223 GLU 223 223 223 GLU GLU A . n 
C 3 224 ALA 224 224 224 ALA ALA A . n 
C 3 225 GLY 225 225 225 GLY GLY A . n 
C 3 226 GLN 226 226 226 GLN GLN A . n 
C 3 227 GLY 227 227 227 GLY GLY A . n 
C 3 228 PRO 228 228 228 PRO PRO A . n 
C 3 229 ILE 229 229 229 ILE ILE A . n 
C 3 230 LYS 230 230 230 LYS LYS A . n 
C 3 231 SER 231 231 231 SER SER A . n 
C 3 232 THR 232 232 232 THR THR A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 ARG 234 234 234 ARG ARG A . n 
C 3 235 ILE 235 235 235 ILE ILE A . n 
C 3 236 TYR 236 236 236 TYR TYR A . n 
C 3 237 PHE 237 237 237 PHE PHE A . n 
C 3 238 LYS 238 238 238 LYS LYS A . n 
C 3 239 PRO 239 239 239 PRO PRO A . n 
C 3 240 LYS 240 240 240 LYS LYS A . n 
C 3 241 HIS 241 241 241 HIS HIS A . n 
C 3 242 VAL 242 242 242 VAL VAL A . n 
C 3 243 LYS 243 243 243 LYS LYS A . n 
C 3 244 ALA 244 244 244 ALA ALA A . n 
C 3 245 TRP 245 245 245 TRP TRP A . n 
C 3 246 VAL 246 246 246 VAL VAL A . n 
C 3 247 PRO 247 247 247 PRO PRO A . n 
C 3 248 ARG 248 248 248 ARG ARG A . n 
C 3 249 PRO 249 249 249 PRO PRO A . n 
C 3 250 PRO 250 250 250 PRO PRO A . n 
C 3 251 ARG 251 251 251 ARG ARG A . n 
C 3 252 LEU 252 252 252 LEU LEU A . n 
C 3 253 CYS 253 253 253 CYS CYS A . n 
C 3 254 GLN 254 254 254 GLN GLN A . n 
C 3 255 TYR 255 255 255 TYR TYR A . n 
C 3 256 GLU 256 256 256 GLU GLU A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 GLN 258 258 258 GLN GLN A . n 
C 3 259 LYS 259 259 259 LYS LYS A . n 
C 3 260 ASN 260 260 260 ASN ASN A . n 
C 3 261 VAL 261 261 261 VAL VAL A . n 
C 3 262 ASN 262 262 262 ASN ASN A . n 
C 3 263 PHE 263 263 263 PHE PHE A . n 
C 3 264 SER 264 264 264 SER SER A . n 
C 3 265 PRO 265 265 265 PRO PRO A . n 
C 3 266 ILE 266 266 266 ILE ILE A . n 
C 3 267 GLY 267 267 267 GLY GLY A . n 
C 3 268 VAL 268 268 268 VAL VAL A . n 
C 3 269 THR 269 269 269 THR THR A . n 
C 3 270 THR 270 270 270 THR THR A . n 
C 3 271 SER 271 271 271 SER SER A . n 
C 3 272 ARG 272 272 272 ARG ARG A . n 
C 3 273 THR 273 273 273 THR THR A . n 
C 3 274 ASP 274 274 274 ASP ASP A . n 
C 3 275 ILE 275 275 275 ILE ILE A . n 
C 3 276 ILE 276 276 276 ILE ILE A . n 
C 3 277 THR 277 277 ?   ?   ?   A . n 
C 3 278 THR 278 278 ?   ?   ?   A . n 
D 4 1   SER 1   1   ?   ?   ?   B . n 
D 4 2   PRO 2   2   ?   ?   ?   B . n 
D 4 3   SER 3   3   ?   ?   ?   B . n 
D 4 4   ALA 4   4   ?   ?   ?   B . n 
D 4 5   GLU 5   5   ?   ?   ?   B . n 
D 4 6   GLU 6   6   ?   ?   ?   B . n 
D 4 7   CYS 7   7   ?   ?   ?   B . n 
D 4 8   GLY 8   8   ?   ?   ?   B . n 
D 4 9   TYR 9   9   ?   ?   ?   B . n 
D 4 10  SER 10  10  ?   ?   ?   B . n 
D 4 11  ASP 11  11  ?   ?   ?   B . n 
D 4 12  ARG 12  12  ?   ?   ?   B . n 
D 4 13  VAL 13  13  ?   ?   ?   B . n 
D 4 14  ARG 14  14  14  ARG ARG B . n 
D 4 15  SER 15  15  15  SER SER B . n 
D 4 16  ILE 16  16  16  ILE ILE B . n 
D 4 17  THR 17  17  17  THR THR B . n 
D 4 18  LEU 18  18  18  LEU LEU B . n 
D 4 19  GLY 19  19  19  GLY GLY B . n 
D 4 20  ASN 20  20  20  ASN ASN B . n 
D 4 21  SER 21  21  21  SER SER B . n 
D 4 22  THR 22  22  22  THR THR B . n 
D 4 23  ILE 23  23  23  ILE ILE B . n 
D 4 24  THR 24  24  24  THR THR B . n 
D 4 25  THR 25  25  25  THR THR B . n 
D 4 26  GLN 26  26  26  GLN GLN B . n 
D 4 27  GLU 27  27  ?   ?   ?   B . n 
D 4 28  CYS 28  28  ?   ?   ?   B . n 
D 4 29  ALA 29  29  ?   ?   ?   B . n 
D 4 30  ASN 30  30  30  ASN ASN B . n 
D 4 31  VAL 31  31  31  VAL VAL B . n 
D 4 32  VAL 32  32  32  VAL VAL B . n 
D 4 33  VAL 33  33  33  VAL VAL B . n 
D 4 34  GLY 34  34  34  GLY GLY B . n 
D 4 35  TYR 35  35  35  TYR TYR B . n 
D 4 36  GLY 36  36  36  GLY GLY B . n 
D 4 37  VAL 37  37  37  VAL VAL B . n 
D 4 38  TRP 38  38  38  TRP TRP B . n 
D 4 39  PRO 39  39  39  PRO PRO B . n 
D 4 40  GLU 40  40  40  GLU GLU B . n 
D 4 41  TYR 41  41  41  TYR TYR B . n 
D 4 42  LEU 42  42  42  LEU LEU B . n 
D 4 43  LYS 43  43  ?   ?   ?   B . n 
D 4 44  ASP 44  44  ?   ?   ?   B . n 
D 4 45  ASN 45  45  ?   ?   ?   B . n 
D 4 46  GLU 46  46  ?   ?   ?   B . n 
D 4 47  ALA 47  47  ?   ?   ?   B . n 
D 4 48  THR 48  48  ?   ?   ?   B . n 
D 4 49  ALA 49  49  ?   ?   ?   B . n 
D 4 50  GLU 50  50  ?   ?   ?   B . n 
D 4 51  ASP 51  51  51  ASP ASP B . n 
D 4 52  GLN 52  52  52  GLN GLN B . n 
D 4 53  PRO 53  53  53  PRO PRO B . n 
D 4 54  THR 54  54  54  THR THR B . n 
D 4 55  GLN 55  55  55  GLN GLN B . n 
D 4 56  PRO 56  56  56  PRO PRO B . n 
D 4 57  ASP 57  57  57  ASP ASP B . n 
D 4 58  VAL 58  58  58  VAL VAL B . n 
D 4 59  ALA 59  59  59  ALA ALA B . n 
D 4 60  THR 60  60  60  THR THR B . n 
D 4 61  CYS 61  61  61  CYS CYS B . n 
D 4 62  ARG 62  62  62  ARG ARG B . n 
D 4 63  PHE 63  63  63  PHE PHE B . n 
D 4 64  TYR 64  64  64  TYR TYR B . n 
D 4 65  THR 65  65  65  THR THR B . n 
D 4 66  LEU 66  66  66  LEU LEU B . n 
D 4 67  GLU 67  67  67  GLU GLU B . n 
D 4 68  SER 68  68  68  SER SER B . n 
D 4 69  VAL 69  69  69  VAL VAL B . n 
D 4 70  GLN 70  70  70  GLN GLN B . n 
D 4 71  TRP 71  71  71  TRP TRP B . n 
D 4 72  MET 72  72  72  MET MET B . n 
D 4 73  LYS 73  73  73  LYS LYS B . n 
D 4 74  ASN 74  74  74  ASN ASN B . n 
D 4 75  SER 75  75  75  SER SER B . n 
D 4 76  ALA 76  76  76  ALA ALA B . n 
D 4 77  GLY 77  77  77  GLY GLY B . n 
D 4 78  TRP 78  78  78  TRP TRP B . n 
D 4 79  TRP 79  79  79  TRP TRP B . n 
D 4 80  TRP 80  80  80  TRP TRP B . n 
D 4 81  LYS 81  81  81  LYS LYS B . n 
D 4 82  LEU 82  82  82  LEU LEU B . n 
D 4 83  PRO 83  83  83  PRO PRO B . n 
D 4 84  ASP 84  84  84  ASP ASP B . n 
D 4 85  ALA 85  85  85  ALA ALA B . n 
D 4 86  LEU 86  86  86  LEU LEU B . n 
D 4 87  SER 87  87  87  SER SER B . n 
D 4 88  GLN 88  88  88  GLN GLN B . n 
D 4 89  MET 89  89  89  MET MET B . n 
D 4 90  GLY 90  90  90  GLY GLY B . n 
D 4 91  LEU 91  91  91  LEU LEU B . n 
D 4 92  PHE 92  92  92  PHE PHE B . n 
D 4 93  GLY 93  93  93  GLY GLY B . n 
D 4 94  GLN 94  94  94  GLN GLN B . n 
D 4 95  ASN 95  95  95  ASN ASN B . n 
D 4 96  MET 96  96  96  MET MET B . n 
D 4 97  GLN 97  97  97  GLN GLN B . n 
D 4 98  TYR 98  98  98  TYR TYR B . n 
D 4 99  HIS 99  99  99  HIS HIS B . n 
D 4 100 TYR 100 100 100 TYR TYR B . n 
D 4 101 LEU 101 101 101 LEU LEU B . n 
D 4 102 GLY 102 102 102 GLY GLY B . n 
D 4 103 ARG 103 103 103 ARG ARG B . n 
D 4 104 THR 104 104 104 THR THR B . n 
D 4 105 GLY 105 105 105 GLY GLY B . n 
D 4 106 TYR 106 106 106 TYR TYR B . n 
D 4 107 THR 107 107 107 THR THR B . n 
D 4 108 ILE 108 108 108 ILE ILE B . n 
D 4 109 HIS 109 109 109 HIS HIS B . n 
D 4 110 VAL 110 110 110 VAL VAL B . n 
D 4 111 GLN 111 111 111 GLN GLN B . n 
D 4 112 CYS 112 112 112 CYS CYS B . n 
D 4 113 ASN 113 113 113 ASN ASN B . n 
D 4 114 ALA 114 114 114 ALA ALA B . n 
D 4 115 SER 115 115 115 SER SER B . n 
D 4 116 LYS 116 116 116 LYS LYS B . n 
D 4 117 PHE 117 117 117 PHE PHE B . n 
D 4 118 HIS 118 118 118 HIS HIS B . n 
D 4 119 GLN 119 119 119 GLN GLN B . n 
D 4 120 GLY 120 120 120 GLY GLY B . n 
D 4 121 CYS 121 121 121 CYS CYS B . n 
D 4 122 LEU 122 122 122 LEU LEU B . n 
D 4 123 LEU 123 123 123 LEU LEU B . n 
D 4 124 VAL 124 124 124 VAL VAL B . n 
D 4 125 VAL 125 125 125 VAL VAL B . n 
D 4 126 CYS 126 126 126 CYS CYS B . n 
D 4 127 VAL 127 127 127 VAL VAL B . n 
D 4 128 PRO 128 128 128 PRO PRO B . n 
D 4 129 GLU 129 129 129 GLU GLU B . n 
D 4 130 ALA 130 130 130 ALA ALA B . n 
D 4 131 GLU 131 131 131 GLU GLU B . n 
D 4 132 MET 132 132 132 MET MET B . n 
D 4 133 GLY 133 133 133 GLY GLY B . n 
D 4 134 CYS 134 134 134 CYS CYS B . n 
D 4 135 SER 135 135 135 SER SER B . n 
D 4 136 ASN 136 136 136 ASN ASN B . n 
D 4 137 LEU 137 137 137 LEU LEU B . n 
D 4 138 ASN 138 138 138 ASN ASN B . n 
D 4 139 ASN 139 139 139 ASN ASN B . n 
D 4 140 THR 140 140 140 THR THR B . n 
D 4 141 PRO 141 141 141 PRO PRO B . n 
D 4 142 GLU 142 142 142 GLU GLU B . n 
D 4 143 PHE 143 143 143 PHE PHE B . n 
D 4 144 SER 144 144 144 SER SER B . n 
D 4 145 GLU 145 145 145 GLU GLU B . n 
D 4 146 LEU 146 146 146 LEU LEU B . n 
D 4 147 SER 147 147 147 SER SER B . n 
D 4 148 GLY 148 148 148 GLY GLY B . n 
D 4 149 GLY 149 149 149 GLY GLY B . n 
D 4 150 ASP 150 150 150 ASP ASP B . n 
D 4 151 SER 151 151 151 SER SER B . n 
D 4 152 ALA 152 152 152 ALA ALA B . n 
D 4 153 ARG 153 153 153 ARG ARG B . n 
D 4 154 MET 154 154 154 MET MET B . n 
D 4 155 PHE 155 155 155 PHE PHE B . n 
D 4 156 THR 156 156 156 THR THR B . n 
D 4 157 ASP 157 157 157 ASP ASP B . n 
D 4 158 THR 158 158 158 THR THR B . n 
D 4 159 GLN 159 159 159 GLN GLN B . n 
D 4 160 VAL 160 160 160 VAL VAL B . n 
D 4 161 GLY 161 161 161 GLY GLY B . n 
D 4 162 GLU 162 162 162 GLU GLU B . n 
D 4 163 SER 163 163 163 SER SER B . n 
D 4 164 ASN 164 164 164 ASN ASN B . n 
D 4 165 ALA 165 165 165 ALA ALA B . n 
D 4 166 LYS 166 166 166 LYS LYS B . n 
D 4 167 LYS 167 167 167 LYS LYS B . n 
D 4 168 VAL 168 168 168 VAL VAL B . n 
D 4 169 GLN 169 169 169 GLN GLN B . n 
D 4 170 THR 170 170 170 THR THR B . n 
D 4 171 ALA 171 171 171 ALA ALA B . n 
D 4 172 VAL 172 172 172 VAL VAL B . n 
D 4 173 TRP 173 173 173 TRP TRP B . n 
D 4 174 ASN 174 174 174 ASN ASN B . n 
D 4 175 ALA 175 175 175 ALA ALA B . n 
D 4 176 GLY 176 176 176 GLY GLY B . n 
D 4 177 MET 177 177 177 MET MET B . n 
D 4 178 GLY 178 178 178 GLY GLY B . n 
D 4 179 VAL 179 179 179 VAL VAL B . n 
D 4 180 GLY 180 180 180 GLY GLY B . n 
D 4 181 VAL 181 181 181 VAL VAL B . n 
D 4 182 GLY 182 182 182 GLY GLY B . n 
D 4 183 ASN 183 183 183 ASN ASN B . n 
D 4 184 LEU 184 184 184 LEU LEU B . n 
D 4 185 THR 185 185 185 THR THR B . n 
D 4 186 ILE 186 186 186 ILE ILE B . n 
D 4 187 PHE 187 187 187 PHE PHE B . n 
D 4 188 PRO 188 188 188 PRO PRO B . n 
D 4 189 HIS 189 189 189 HIS HIS B . n 
D 4 190 GLN 190 190 190 GLN GLN B . n 
D 4 191 TRP 191 191 191 TRP TRP B . n 
D 4 192 ILE 192 192 192 ILE ILE B . n 
D 4 193 ASN 193 193 193 ASN ASN B . n 
D 4 194 LEU 194 194 194 LEU LEU B . n 
D 4 195 ARG 195 195 195 ARG ARG B . n 
D 4 196 THR 196 196 196 THR THR B . n 
D 4 197 ASN 197 197 197 ASN ASN B . n 
D 4 198 ASN 198 198 198 ASN ASN B . n 
D 4 199 SER 199 199 199 SER SER B . n 
D 4 200 ALA 200 200 200 ALA ALA B . n 
D 4 201 THR 201 201 201 THR THR B . n 
D 4 202 LEU 202 202 202 LEU LEU B . n 
D 4 203 VAL 203 203 203 VAL VAL B . n 
D 4 204 MET 204 204 204 MET MET B . n 
D 4 205 PRO 205 205 205 PRO PRO B . n 
D 4 206 TYR 206 206 206 TYR TYR B . n 
D 4 207 ILE 207 207 207 ILE ILE B . n 
D 4 208 ASN 208 208 208 ASN ASN B . n 
D 4 209 SER 209 209 209 SER SER B . n 
D 4 210 VAL 210 210 210 VAL VAL B . n 
D 4 211 PRO 211 211 211 PRO PRO B . n 
D 4 212 MET 212 212 212 MET MET B . n 
D 4 213 ASP 213 213 213 ASP ASP B . n 
D 4 214 ASN 214 214 214 ASN ASN B . n 
D 4 215 MET 215 215 215 MET MET B . n 
D 4 216 PHE 216 216 216 PHE PHE B . n 
D 4 217 ARG 217 217 217 ARG ARG B . n 
D 4 218 HIS 218 218 218 HIS HIS B . n 
D 4 219 ASN 219 219 219 ASN ASN B . n 
D 4 220 ASN 220 220 220 ASN ASN B . n 
D 4 221 LEU 221 221 221 LEU LEU B . n 
D 4 222 THR 222 222 222 THR THR B . n 
D 4 223 LEU 223 223 223 LEU LEU B . n 
D 4 224 MET 224 224 224 MET MET B . n 
D 4 225 ILE 225 225 225 ILE ILE B . n 
D 4 226 ILE 226 226 226 ILE ILE B . n 
D 4 227 PRO 227 227 227 PRO PRO B . n 
D 4 228 PHE 228 228 228 PHE PHE B . n 
D 4 229 VAL 229 229 229 VAL VAL B . n 
D 4 230 PRO 230 230 230 PRO PRO B . n 
D 4 231 LEU 231 231 231 LEU LEU B . n 
D 4 232 ASN 232 232 232 ASN ASN B . n 
D 4 233 TYR 233 233 233 TYR TYR B . n 
D 4 234 SER 234 234 234 SER SER B . n 
D 4 235 GLU 235 235 235 GLU GLU B . n 
D 4 236 GLY 236 236 236 GLY GLY B . n 
D 4 237 SER 237 237 237 SER SER B . n 
D 4 238 SER 238 238 238 SER SER B . n 
D 4 239 PRO 239 239 239 PRO PRO B . n 
D 4 240 TYR 240 240 240 TYR TYR B . n 
D 4 241 VAL 241 241 241 VAL VAL B . n 
D 4 242 PRO 242 242 242 PRO PRO B . n 
D 4 243 ILE 243 243 243 ILE ILE B . n 
D 4 244 THR 244 244 244 THR THR B . n 
D 4 245 VAL 245 245 245 VAL VAL B . n 
D 4 246 THR 246 246 246 THR THR B . n 
D 4 247 ILE 247 247 247 ILE ILE B . n 
D 4 248 ALA 248 248 248 ALA ALA B . n 
D 4 249 PRO 249 249 249 PRO PRO B . n 
D 4 250 MET 250 250 250 MET MET B . n 
D 4 251 CYS 251 251 251 CYS CYS B . n 
D 4 252 ALA 252 252 252 ALA ALA B . n 
D 4 253 GLU 253 253 253 GLU GLU B . n 
D 4 254 TYR 254 254 254 TYR TYR B . n 
D 4 255 ASN 255 255 255 ASN ASN B . n 
D 4 256 GLY 256 256 256 GLY GLY B . n 
D 4 257 LEU 257 257 257 LEU LEU B . n 
D 4 258 ARG 258 258 ?   ?   ?   B . n 
D 4 259 LEU 259 259 ?   ?   ?   B . n 
D 4 260 ALA 260 260 ?   ?   ?   B . n 
D 4 261 SER 261 261 ?   ?   ?   B . n 
D 4 262 ASN 262 262 ?   ?   ?   B . n 
D 4 263 GLN 263 263 ?   ?   ?   B . n 
E 5 1   GLY 1   1   1   GLY GLY C . n 
E 5 2   LEU 2   2   2   LEU LEU C . n 
E 5 3   PRO 3   3   3   PRO PRO C . n 
E 5 4   VAL 4   4   4   VAL VAL C . n 
E 5 5   MET 5   5   5   MET MET C . n 
E 5 6   THR 6   6   6   THR THR C . n 
E 5 7   THR 7   7   7   THR THR C . n 
E 5 8   PRO 8   8   8   PRO PRO C . n 
E 5 9   GLY 9   9   9   GLY GLY C . n 
E 5 10  SER 10  10  10  SER SER C . n 
E 5 11  THR 11  11  11  THR THR C . n 
E 5 12  GLN 12  12  12  GLN GLN C . n 
E 5 13  PHE 13  13  13  PHE PHE C . n 
E 5 14  LEU 14  14  14  LEU LEU C . n 
E 5 15  THR 15  15  15  THR THR C . n 
E 5 16  SER 16  16  16  SER SER C . n 
E 5 17  ASP 17  17  17  ASP ASP C . n 
E 5 18  ASP 18  18  18  ASP ASP C . n 
E 5 19  PHE 19  19  19  PHE PHE C . n 
E 5 20  GLN 20  20  20  GLN GLN C . n 
E 5 21  SER 21  21  21  SER SER C . n 
E 5 22  PRO 22  22  22  PRO PRO C . n 
E 5 23  SER 23  23  23  SER SER C . n 
E 5 24  ALA 24  24  24  ALA ALA C . n 
E 5 25  MET 25  25  25  MET MET C . n 
E 5 26  PRO 26  26  26  PRO PRO C . n 
E 5 27  GLN 27  27  27  GLN GLN C . n 
E 5 28  PHE 28  28  28  PHE PHE C . n 
E 5 29  ASP 29  29  29  ASP ASP C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  THR 31  31  31  THR THR C . n 
E 5 32  PRO 32  32  32  PRO PRO C . n 
E 5 33  GLU 33  33  33  GLU GLU C . n 
E 5 34  MET 34  34  34  MET MET C . n 
E 5 35  GLN 35  35  35  GLN GLN C . n 
E 5 36  ILE 36  36  36  ILE ILE C . n 
E 5 37  PRO 37  37  37  PRO PRO C . n 
E 5 38  GLY 38  38  38  GLY GLY C . n 
E 5 39  ARG 39  39  39  ARG ARG C . n 
E 5 40  VAL 40  40  40  VAL VAL C . n 
E 5 41  ASN 41  41  41  ASN ASN C . n 
E 5 42  ASN 42  42  42  ASN ASN C . n 
E 5 43  LEU 43  43  43  LEU LEU C . n 
E 5 44  MET 44  44  44  MET MET C . n 
E 5 45  GLU 45  45  45  GLU GLU C . n 
E 5 46  ILE 46  46  46  ILE ILE C . n 
E 5 47  ALA 47  47  47  ALA ALA C . n 
E 5 48  GLU 48  48  48  GLU GLU C . n 
E 5 49  VAL 49  49  49  VAL VAL C . n 
E 5 50  ASP 50  50  50  ASP ASP C . n 
E 5 51  SER 51  51  51  SER SER C . n 
E 5 52  VAL 52  52  52  VAL VAL C . n 
E 5 53  VAL 53  53  53  VAL VAL C . n 
E 5 54  PRO 54  54  54  PRO PRO C . n 
E 5 55  VAL 55  55  55  VAL VAL C . n 
E 5 56  ASN 56  56  56  ASN ASN C . n 
E 5 57  ASN 57  57  57  ASN ASN C . n 
E 5 58  THR 58  58  58  THR THR C . n 
E 5 59  GLU 59  59  59  GLU GLU C . n 
E 5 60  ASP 60  60  60  ASP ASP C . n 
E 5 61  ASN 61  61  61  ASN ASN C . n 
E 5 62  VAL 62  62  62  VAL VAL C . n 
E 5 63  SER 63  63  63  SER SER C . n 
E 5 64  SER 64  64  64  SER SER C . n 
E 5 65  LEU 65  65  65  LEU LEU C . n 
E 5 66  LYS 66  66  66  LYS LYS C . n 
E 5 67  ALA 67  67  67  ALA ALA C . n 
E 5 68  TYR 68  68  68  TYR TYR C . n 
E 5 69  GLN 69  69  69  GLN GLN C . n 
E 5 70  ILE 70  70  70  ILE ILE C . n 
E 5 71  PRO 71  71  71  PRO PRO C . n 
E 5 72  VAL 72  72  72  VAL VAL C . n 
E 5 73  GLN 73  73  73  GLN GLN C . n 
E 5 74  SER 74  74  74  SER SER C . n 
E 5 75  ASN 75  75  75  ASN ASN C . n 
E 5 76  SER 76  76  76  SER SER C . n 
E 5 77  ASP 77  77  77  ASP ASP C . n 
E 5 78  ASN 78  78  78  ASN ASN C . n 
E 5 79  GLY 79  79  79  GLY GLY C . n 
E 5 80  LYS 80  80  80  LYS LYS C . n 
E 5 81  GLN 81  81  81  GLN GLN C . n 
E 5 82  VAL 82  82  82  VAL VAL C . n 
E 5 83  PHE 83  83  83  PHE PHE C . n 
E 5 84  GLY 84  84  84  GLY GLY C . n 
E 5 85  PHE 85  85  85  PHE PHE C . n 
E 5 86  PRO 86  86  86  PRO PRO C . n 
E 5 87  LEU 87  87  87  LEU LEU C . n 
E 5 88  GLN 88  88  88  GLN GLN C . n 
E 5 89  PRO 89  89  89  PRO PRO C . n 
E 5 90  GLY 90  90  90  GLY GLY C . n 
E 5 91  ALA 91  91  91  ALA ALA C . n 
E 5 92  ASN 92  92  92  ASN ASN C . n 
E 5 93  ASN 93  93  93  ASN ASN C . n 
E 5 94  VAL 94  94  94  VAL VAL C . n 
E 5 95  LEU 95  95  95  LEU LEU C . n 
E 5 96  ASN 96  96  96  ASN ASN C . n 
E 5 97  ARG 97  97  97  ARG ARG C . n 
E 5 98  THR 98  98  98  THR THR C . n 
E 5 99  LEU 99  99  99  LEU LEU C . n 
E 5 100 LEU 100 100 100 LEU LEU C . n 
E 5 101 GLY 101 101 101 GLY GLY C . n 
E 5 102 GLU 102 102 102 GLU GLU C . n 
E 5 103 ILE 103 103 103 ILE ILE C . n 
E 5 104 LEU 104 104 104 LEU LEU C . n 
E 5 105 ASN 105 105 105 ASN ASN C . n 
E 5 106 TYR 106 106 106 TYR TYR C . n 
E 5 107 TYR 107 107 107 TYR TYR C . n 
E 5 108 THR 108 108 108 THR THR C . n 
E 5 109 HIS 109 109 109 HIS HIS C . n 
E 5 110 TRP 110 110 110 TRP TRP C . n 
E 5 111 SER 111 111 111 SER SER C . n 
E 5 112 GLY 112 112 112 GLY GLY C . n 
E 5 113 SER 113 113 113 SER SER C . n 
E 5 114 ILE 114 114 114 ILE ILE C . n 
E 5 115 LYS 115 115 115 LYS LYS C . n 
E 5 116 LEU 116 116 116 LEU LEU C . n 
E 5 117 THR 117 117 117 THR THR C . n 
E 5 118 PHE 118 118 118 PHE PHE C . n 
E 5 119 MET 119 119 119 MET MET C . n 
E 5 120 PHE 120 120 120 PHE PHE C . n 
E 5 121 CYS 121 121 121 CYS CYS C . n 
E 5 122 GLY 122 122 122 GLY GLY C . n 
E 5 123 SER 123 123 123 SER SER C . n 
E 5 124 ALA 124 124 124 ALA ALA C . n 
E 5 125 MET 125 125 125 MET MET C . n 
E 5 126 ALA 126 126 126 ALA ALA C . n 
E 5 127 THR 127 127 127 THR THR C . n 
E 5 128 GLY 128 128 128 GLY GLY C . n 
E 5 129 LYS 129 129 129 LYS LYS C . n 
E 5 130 PHE 130 130 130 PHE PHE C . n 
E 5 131 LEU 131 131 131 LEU LEU C . n 
E 5 132 LEU 132 132 132 LEU LEU C . n 
E 5 133 ALA 133 133 133 ALA ALA C . n 
E 5 134 TYR 134 134 134 TYR TYR C . n 
E 5 135 SER 135 135 135 SER SER C . n 
E 5 136 PRO 136 136 136 PRO PRO C . n 
E 5 137 PRO 137 137 137 PRO PRO C . n 
E 5 138 GLY 138 138 138 GLY GLY C . n 
E 5 139 ALA 139 139 139 ALA ALA C . n 
E 5 140 GLY 140 140 140 GLY GLY C . n 
E 5 141 VAL 141 141 141 VAL VAL C . n 
E 5 142 PRO 142 142 142 PRO PRO C . n 
E 5 143 LYS 143 143 143 LYS LYS C . n 
E 5 144 ASN 144 144 144 ASN ASN C . n 
E 5 145 ARG 145 145 145 ARG ARG C . n 
E 5 146 LYS 146 146 146 LYS LYS C . n 
E 5 147 ASP 147 147 147 ASP ASP C . n 
E 5 148 ALA 148 148 148 ALA ALA C . n 
E 5 149 MET 149 149 149 MET MET C . n 
E 5 150 LEU 150 150 150 LEU LEU C . n 
E 5 151 GLY 151 151 151 GLY GLY C . n 
E 5 152 THR 152 152 152 THR THR C . n 
E 5 153 HIS 153 153 153 HIS HIS C . n 
E 5 154 VAL 154 154 154 VAL VAL C . n 
E 5 155 ILE 155 155 155 ILE ILE C . n 
E 5 156 TRP 156 156 156 TRP TRP C . n 
E 5 157 ASP 157 157 157 ASP ASP C . n 
E 5 158 VAL 158 158 158 VAL VAL C . n 
E 5 159 GLY 159 159 159 GLY GLY C . n 
E 5 160 LEU 160 160 160 LEU LEU C . n 
E 5 161 GLN 161 161 161 GLN GLN C . n 
E 5 162 SER 162 162 162 SER SER C . n 
E 5 163 SER 163 163 163 SER SER C . n 
E 5 164 CYS 164 164 164 CYS CYS C . n 
E 5 165 VAL 165 165 165 VAL VAL C . n 
E 5 166 LEU 166 166 166 LEU LEU C . n 
E 5 167 CYS 167 167 167 CYS CYS C . n 
E 5 168 VAL 168 168 168 VAL VAL C . n 
E 5 169 PRO 169 169 169 PRO PRO C . n 
E 5 170 TRP 170 170 170 TRP TRP C . n 
E 5 171 ILE 171 171 171 ILE ILE C . n 
E 5 172 SER 172 172 172 SER SER C . n 
E 5 173 GLN 173 173 ?   ?   ?   C . n 
E 5 174 THR 174 174 ?   ?   ?   C . n 
E 5 175 HIS 175 175 ?   ?   ?   C . n 
E 5 176 TYR 176 176 ?   ?   ?   C . n 
E 5 177 ARG 177 177 ?   ?   ?   C . n 
E 5 178 TYR 178 178 ?   ?   ?   C . n 
E 5 179 VAL 179 179 ?   ?   ?   C . n 
E 5 180 VAL 180 180 ?   ?   ?   C . n 
E 5 181 GLU 181 181 ?   ?   ?   C . n 
E 5 182 ASP 182 182 ?   ?   ?   C . n 
E 5 183 GLU 183 183 ?   ?   ?   C . n 
E 5 184 TYR 184 184 ?   ?   ?   C . n 
E 5 185 THR 185 185 ?   ?   ?   C . n 
E 5 186 ALA 186 186 186 ALA ALA C . n 
E 5 187 ALA 187 187 187 ALA ALA C . n 
E 5 188 GLY 188 188 188 GLY GLY C . n 
E 5 189 TYR 189 189 189 TYR TYR C . n 
E 5 190 VAL 190 190 190 VAL VAL C . n 
E 5 191 THR 191 191 191 THR THR C . n 
E 5 192 CYS 192 192 192 CYS CYS C . n 
E 5 193 TRP 193 193 193 TRP TRP C . n 
E 5 194 TYR 194 194 194 TYR TYR C . n 
E 5 195 GLN 195 195 195 GLN GLN C . n 
E 5 196 THR 196 196 196 THR THR C . n 
E 5 197 ASN 197 197 197 ASN ASN C . n 
E 5 198 ILE 198 198 198 ILE ILE C . n 
E 5 199 VAL 199 199 199 VAL VAL C . n 
E 5 200 VAL 200 200 200 VAL VAL C . n 
E 5 201 PRO 201 201 201 PRO PRO C . n 
E 5 202 ALA 202 202 202 ALA ALA C . n 
E 5 203 ASP 203 203 203 ASP ASP C . n 
E 5 204 VAL 204 204 204 VAL VAL C . n 
E 5 205 GLN 205 205 205 GLN GLN C . n 
E 5 206 SER 206 206 206 SER SER C . n 
E 5 207 SER 207 207 207 SER SER C . n 
E 5 208 CYS 208 208 208 CYS CYS C . n 
E 5 209 ASP 209 209 209 ASP ASP C . n 
E 5 210 ILE 210 210 210 ILE ILE C . n 
E 5 211 LEU 211 211 211 LEU LEU C . n 
E 5 212 CYS 212 212 212 CYS CYS C . n 
E 5 213 PHE 213 213 213 PHE PHE C . n 
E 5 214 VAL 214 214 214 VAL VAL C . n 
E 5 215 SER 215 215 215 SER SER C . n 
E 5 216 ALA 216 216 216 ALA ALA C . n 
E 5 217 CYS 217 217 217 CYS CYS C . n 
E 5 218 ASN 218 218 218 ASN ASN C . n 
E 5 219 ASP 219 219 219 ASP ASP C . n 
E 5 220 PHE 220 220 220 PHE PHE C . n 
E 5 221 SER 221 221 221 SER SER C . n 
E 5 222 VAL 222 222 222 VAL VAL C . n 
E 5 223 ARG 223 223 223 ARG ARG C . n 
E 5 224 MET 224 224 224 MET MET C . n 
E 5 225 LEU 225 225 225 LEU LEU C . n 
E 5 226 LYS 226 226 226 LYS LYS C . n 
E 5 227 ASP 227 227 227 ASP ASP C . n 
E 5 228 THR 228 228 228 THR THR C . n 
E 5 229 PRO 229 229 229 PRO PRO C . n 
E 5 230 PHE 230 230 230 PHE PHE C . n 
E 5 231 ILE 231 231 231 ILE ILE C . n 
E 5 232 ARG 232 232 232 ARG ARG C . n 
E 5 233 GLN 233 233 233 GLN GLN C . n 
E 5 234 ASP 234 234 234 ASP ASP C . n 
E 5 235 THR 235 235 235 THR THR C . n 
E 5 236 PHE 236 236 236 PHE PHE C . n 
E 5 237 TYR 237 237 237 TYR TYR C . n 
E 5 238 GLN 238 238 238 GLN GLN C . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              abing0811@xmu.edu.cn 
_pdbx_contact_author.name_first         Qingbing 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7516-9965 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     -0.80901699 -0.30901699 0.50000000  208.21942  0.50000000  -0.80901699 0.30901699  
0.34610    0.30901699  0.50000000  0.80901699  -542.75332 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  336.34610  0.80901700  0.30901699  -0.50000000 
127.78058  0.30901699  0.50000000  0.80901700  -207.87332 
3  'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901700  336.90610  0.50000000  -0.80901700 -0.30901700 
543.31333  0.80901699  0.30901700  0.50000000  -208.21942 
4  'point symmetry operation' ?     ?     -0.30901700 0.50000000  0.80901700  0.90610    -0.50000000 -0.80901699 0.30901700  
672.34610  0.80901700  -0.30901699 0.50000000  -0.56000   
5  'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901700  -207.31332 -0.80901699 0.30901700  0.50000000  
336.56000  0.30901700  -0.50000000 0.80901699  128.12668  
6  'point symmetry operation' ?     ?     -0.80901699 0.30901700  0.50000001  336.56000  0.30901699  -0.50000000 0.80901699  
129.24668  0.49999999  0.80901700  0.30901699  -208.43332 
7  'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
1.12000    1.00000000  0.00000000  0.00000000  -1.12000   
8  'point symmetry operation' ?     ?     0.80901700  0.30901699  -0.50000000 127.78058  0.30901699  0.50000000  0.80901699  
-206.75332 0.50000000  -0.80901700 0.30901699  335.22610  
9  'point symmetry operation' ?     ?     0.50000000  -0.80901700 -0.30901699 543.31332  0.80901699  0.30901699  0.50000000  
-207.09942 -0.30901700 -0.50000000 0.80901699  335.78610  
10 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901700  672.34610  0.80901699  -0.30901700 0.50000000  
0.56000    -0.30901700 0.50000000  0.80901699  -0.21390   
11 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  672.34610  -0.80901700 0.30901699  -0.49999999 
671.44000  0.30901700  -0.50000001 -0.80901699 669.97390  
12 'point symmetry operation' ?     ?     -0.80901700 0.30901700  0.50000000  336.56000  -0.30901700 0.50000000  -0.80901699 
542.75332  -0.50000000 -0.80901700 -0.30901699 878.19332  
13 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
670.88000  -1.00000000 0.00000000  0.00000000  670.88000  
14 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 127.78058  -0.30901699 -0.50000000 -0.80901700 
878.75332  -0.50000000 0.80901700  -0.30901699 334.53390  
15 'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901700 543.31333  -0.80901699 -0.30901700 -0.50000000 
879.09942  0.30901700  0.50000000  -0.80901699 333.97390  
16 'point symmetry operation' ?     ?     0.30901699  0.49999999  -0.80901700 335.09390  0.50000001  -0.80901699 -0.30901700 
543.31332  -0.80901699 -0.30901699 -0.50000000 877.97942  
17 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901700 671.09391  -0.50000000 -0.80901699 0.30901699  
672.34610  -0.80901699 0.30901700  -0.50000000 670.32000  
18 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901700 879.31333  -0.80901700 0.30901699  0.50000000  
336.56000  -0.30901699 0.50000000  -0.80901699 541.63332  
19 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  672.00000  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 669.76000  
20 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901700 335.65390  0.80901699  0.30901700  -0.50000000 
127.78058  -0.30901700 -0.50000000 -0.80901699 877.63332  
21 'point symmetry operation' ?     ?     -0.49999999 -0.80901700 -0.30901699 879.31332  0.80901699  -0.30901700 -0.50000001 
335.44000  0.30901699  -0.50000000 0.80901699  128.12668  
22 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  672.00000  0.00000000  -1.00000000 0.00000000  
672.00001  0.00000000  0.00000000  1.00000000  0.00000    
23 'point symmetry operation' ?     ?     -0.50000000 0.80901700  -0.30901699 335.65390  -0.80901700 -0.30901699 0.50000000  
544.21942  0.30901699  0.50000000  0.80901699  -207.87332 
24 'point symmetry operation' ?     ?     0.30901700  0.50000000  -0.80901699 335.09390  -0.50000000 0.80901700  0.30901699  
128.68668  0.80901699  0.30901699  0.50000000  -208.21942 
25 'point symmetry operation' ?     ?     0.30901700  -0.50000000 -0.80901699 671.09390  0.50000000  0.80901699  -0.30901700 
-0.34610   0.80901699  -0.30901700 0.50000000  -0.56000   
26 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 670.88000  -1.00000000 0.00000000  0.00000000  
672.00000  0.00000000  1.00000000  0.00000000  -1.12000   
27 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901700 878.75332  -0.50000000 0.80901699  -0.30901699 
335.65390  0.80901700  0.30901699  -0.50000000 126.66058  
28 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 -0.50000000 879.09942  0.30901699  0.50000000  -0.80901700 
335.09390  0.50000000  -0.80901700 -0.30901700 542.19332  
29 'point symmetry operation' ?     ?     -0.80901700 0.30901699  -0.50000000 671.44000  0.30901700  -0.50000000 -0.80901700 
671.09391  -0.50000000 -0.80901699 0.30901700  671.22610  
30 'point symmetry operation' ?     ?     -0.30901700 0.50000000  -0.80901699 542.75332  -0.50000000 -0.80901699 -0.30901700 
879.31333  -0.80901699 0.30901700  0.50000000  335.44000  
31 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  -207.09942 -0.30901699 -0.49999999 0.80901700  
336.90610  0.50000001  -0.80901699 -0.30901700 542.19332  
32 'point symmetry operation' ?     ?     0.80901699  -0.30901700 0.50000000  0.56000    -0.30901699 0.50000000  0.80901700  
0.90610    -0.50000000 -0.80901699 0.30901699  671.22610  
33 'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  129.24668  0.50000000  0.80901699  0.30901700  
-207.31332 -0.80901700 0.30901699  0.50000000  335.44000  
34 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  1.12000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  -1.12000   
35 'point symmetry operation' ?     ?     0.30901700  0.50000000  0.80901699  -206.75332 0.50000000  -0.80901699 0.30901700  
336.34610  0.80901699  0.30901700  -0.50000000 126.66058  
36 'point symmetry operation' ?     ?     -0.30901700 0.50000001  0.80901699  0.90610    0.50000000  0.80901699  -0.30901699 
-0.34610   -0.80901700 0.30901699  -0.49999999 670.32000  
37 'point symmetry operation' ?     ?     0.50000000  0.80901700  0.30901699  -207.31332 0.80901700  -0.30901700 -0.50000000 
335.44000  -0.30901700 0.50000000  -0.80901699 541.63332  
38 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
672.00000  0.00000000  0.00000000  -1.00000000 669.76000  
39 'point symmetry operation' ?     ?     0.50000000  -0.80901700 0.30901699  336.34610  -0.80901699 -0.30901699 0.50000000  
544.21942  -0.30901699 -0.50000000 -0.80901700 877.63332  
40 'point symmetry operation' ?     ?     -0.30901700 -0.50000000 0.80901699  336.90610  -0.50000000 0.80901699  0.30901700  
128.68668  -0.80901699 -0.30901700 -0.50000000 877.97942  
41 'point symmetry operation' ?     ?     -0.50000001 0.80901699  0.30901700  128.68668  -0.80901699 -0.30901699 -0.50000000 
879.09942  -0.30901699 -0.49999999 0.80901700  335.78610  
42 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 -0.34610   -0.80901699 0.30901700  -0.50000000 
671.44000  -0.30901699 0.50000000  0.80901700  -0.21390   
43 'point symmetry operation' ?     ?     0.80901700  -0.30901699 -0.50000000 335.44000  -0.30901699 0.50000000  -0.80901699 
542.75332  0.50000000  0.80901699  0.30901700  -208.43332 
44 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  672.00000  0.00000000  0.00000000  -1.00000000 
670.88000  1.00000000  0.00000000  0.00000000  -1.12000   
45 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 0.50000000  544.21942  -0.30901700 -0.50000000 -0.80901699 
878.75333  0.50000000  -0.80901699 0.30901700  335.22610  
46 'point symmetry operation' ?     ?     0.80901700  -0.30901699 0.49999999  0.56000    0.30901700  -0.50000001 -0.80901699 
671.09390  0.50000000  0.80901699  -0.30901699 -1.46610   
47 'point symmetry operation' ?     ?     0.30901700  -0.50000000 0.80901699  129.24668  -0.50000000 -0.80901700 -0.30901699 
879.31332  0.80901700  -0.30901700 -0.50000000 334.32000  
48 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  1.12000    -1.00000000 0.00000000  0.00000000  
672.00000  0.00000000  -1.00000000 0.00000000  670.88000  
49 'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901700  -206.75332 -0.50000000 0.80901700  -0.30901699 
335.65390  -0.80901699 -0.30901699 0.50000000  543.09942  
50 'point symmetry operation' ?     ?     0.80901699  0.30901700  0.50000000  -207.09942 0.30901700  0.50000000  -0.80901699 
335.09390  -0.50000000 0.80901699  0.30901700  127.56668  
51 'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 542.75332  0.49999999  0.80901700  0.30901699  
-207.31332 0.80901699  -0.30901700 -0.50000001 334.32000  
52 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 670.88000  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  670.88000  
53 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 878.75333  0.50000000  -0.80901700 0.30901699  
336.34610  -0.80901700 -0.30901699 0.50000000  543.09942  
54 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 879.09942  -0.30901700 -0.50000000 0.80901699  
336.90610  -0.50000000 0.80901700  0.30901699  127.56668  
55 'point symmetry operation' ?     ?     -0.80901699 0.30901700  -0.50000000 671.44000  -0.30901700 0.50000000  0.80901699  
0.90610    0.50000000  0.80901699  -0.30901700 -1.46610   
56 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  672.00000  0.00000000  0.00000000  1.00000000  
1.12000    -1.00000000 0.00000000  0.00000000  670.88000  
57 'point symmetry operation' ?     ?     -0.80901700 -0.30901699 0.50000000  544.21942  0.30901699  0.50000000  0.80901700  
-206.75332 -0.50000000 0.80901699  -0.30901699 334.53390  
58 'point symmetry operation' ?     ?     -0.50000000 0.80901700  0.30901700  128.68668  0.80901699  0.30901700  0.50000000  
-207.09942 0.30901699  0.50000000  -0.80901700 333.97390  
59 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901700 -0.34610   0.80901700  -0.30901699 0.50000000  
0.56000    0.30901700  -0.50000000 -0.80901700 669.97390  
60 'point symmetry operation' ?     ?     0.80901699  -0.30901700 -0.50000000 335.44000  0.30901700  -0.50000000 0.80901699  
129.24668  -0.50000000 -0.80901699 -0.30901700 878.19332  
# 
_pdbx_point_symmetry.entry_id             7X38 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2022-09-28 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.14_3259: 
_software.pdbx_ordinal           1 
# 
_em_3d_fitting.entry_id          7X38 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7X38 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               12131 
_em_3d_reconstruction.resolution                  3.52 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.details              ? 
_em_entity_assembly.name                 'Coxsackievirus B1' 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 VIRUS 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7X38 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI TECNAI F30' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             3400 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_virus_entity.entity_assembly_id    1 
_em_virus_entity.empty                 NO 
_em_virus_entity.enveloped             YES 
_em_virus_entity.virus_isolate         STRAIN 
_em_virus_entity.virus_type            VIRION 
_em_virus_entity.id                    1 
_em_virus_entity.virus_host_category   ? 
_em_virus_entity.details               ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7X38 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7X38 
_em_experiment.id                      1 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             SER 
_pdbx_validate_rmsd_angle.auth_seq_id_1              60 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             SER 
_pdbx_validate_rmsd_angle.auth_seq_id_2              60 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             SER 
_pdbx_validate_rmsd_angle.auth_seq_id_3              60 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                100.86 
_pdbx_validate_rmsd_angle.angle_target_value         110.50 
_pdbx_validate_rmsd_angle.angle_deviation            -9.64 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.50 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR L 50  ? ? -151.25 -157.17 
2  1 THR H 30  ? ? -93.80  31.59   
3  1 GLN H 43  ? ? -123.92 -168.71 
4  1 ALA H 102 ? ? 72.85   -10.60  
5  1 ASP H 103 ? ? -142.27 -14.10  
6  1 LYS A 85  ? ? -141.33 -13.18  
7  1 ALA A 129 ? ? -171.26 -173.74 
8  1 SER A 130 ? ? 66.14   65.45   
9  1 SER A 131 ? ? 62.62   69.24   
10 1 ASN A 173 ? ? -126.36 -169.57 
11 1 ASN A 208 ? ? 57.66   76.23   
12 1 VAL A 246 ? ? 55.91   80.97   
13 1 THR B 25  ? ? -123.23 -162.72 
14 1 ASN B 74  ? ? -93.81  53.20   
15 1 PRO B 83  ? ? -87.87  41.85   
16 1 ASP B 84  ? ? -131.23 -30.84  
17 1 SER C 10  ? ? -96.98  -64.81  
18 1 THR C 11  ? ? -93.52  52.68   
19 1 ASP C 29  ? ? 60.39   72.52   
20 1 ASN C 56  ? ? -117.29 54.19   
21 1 GLU C 59  ? ? 69.84   -9.10   
22 1 SER C 63  ? ? -95.34  51.27   
23 1 VAL C 82  ? ? -91.15  -60.78  
24 1 PHE C 220 ? ? -79.83  -169.80 
25 1 MET C 224 ? ? 60.08   72.08   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 H GLN 1   ? B GLN 1   
2   1 Y 1 A GLY 1   ? C GLY 1   
3   1 Y 1 A PRO 2   ? C PRO 2   
4   1 Y 1 A VAL 3   ? C VAL 3   
5   1 Y 1 A GLU 4   ? C GLU 4   
6   1 Y 1 A GLU 5   ? C GLU 5   
7   1 Y 1 A SER 6   ? C SER 6   
8   1 Y 1 A VAL 7   ? C VAL 7   
9   1 Y 1 A ASP 8   ? C ASP 8   
10  1 Y 1 A ARG 9   ? C ARG 9   
11  1 Y 1 A ALA 10  ? C ALA 10  
12  1 Y 1 A VAL 11  ? C VAL 11  
13  1 Y 1 A ALA 12  ? C ALA 12  
14  1 Y 1 A ARG 13  ? C ARG 13  
15  1 Y 1 A VAL 14  ? C VAL 14  
16  1 Y 1 A ALA 15  ? C ALA 15  
17  1 Y 1 A ASP 16  ? C ASP 16  
18  1 Y 1 A THR 17  ? C THR 17  
19  1 Y 1 A ILE 18  ? C ILE 18  
20  1 Y 1 A SER 19  ? C SER 19  
21  1 Y 1 A SER 20  ? C SER 20  
22  1 Y 1 A ARG 21  ? C ARG 21  
23  1 Y 1 A PRO 22  ? C PRO 22  
24  1 Y 1 A THR 23  ? C THR 23  
25  1 Y 1 A ASN 24  ? C ASN 24  
26  1 Y 1 A SER 25  ? C SER 25  
27  1 Y 1 A GLU 26  ? C GLU 26  
28  1 Y 1 A SER 27  ? C SER 27  
29  1 Y 1 A ILE 28  ? C ILE 28  
30  1 Y 1 A PRO 29  ? C PRO 29  
31  1 Y 1 A ALA 30  ? C ALA 30  
32  1 Y 1 A LEU 31  ? C LEU 31  
33  1 Y 1 A THR 32  ? C THR 32  
34  1 Y 1 A ALA 33  ? C ALA 33  
35  1 Y 1 A ALA 34  ? C ALA 34  
36  1 Y 1 A GLU 35  ? C GLU 35  
37  1 Y 1 A THR 36  ? C THR 36  
38  1 Y 1 A GLY 37  ? C GLY 37  
39  1 Y 1 A HIS 38  ? C HIS 38  
40  1 Y 1 A THR 39  ? C THR 39  
41  1 Y 1 A SER 40  ? C SER 40  
42  1 Y 1 A GLN 41  ? C GLN 41  
43  1 Y 1 A VAL 42  ? C VAL 42  
44  1 Y 1 A VAL 43  ? C VAL 43  
45  1 Y 1 A PRO 44  ? C PRO 44  
46  1 Y 1 A SER 45  ? C SER 45  
47  1 Y 1 A ASP 46  ? C ASP 46  
48  1 Y 1 A THR 47  ? C THR 47  
49  1 Y 1 A MET 48  ? C MET 48  
50  1 Y 1 A GLN 49  ? C GLN 49  
51  1 Y 1 A THR 50  ? C THR 50  
52  1 Y 1 A ARG 51  ? C ARG 51  
53  1 Y 1 A HIS 52  ? C HIS 52  
54  1 Y 1 A VAL 53  ? C VAL 53  
55  1 Y 1 A LYS 54  ? C LYS 54  
56  1 Y 1 A ASN 55  ? C ASN 55  
57  1 Y 1 A TYR 56  ? C TYR 56  
58  1 Y 1 A HIS 57  ? C HIS 57  
59  1 Y 1 A GLN 198 ? C GLN 198 
60  1 Y 1 A PHE 199 ? C PHE 199 
61  1 Y 1 A SER 200 ? C SER 200 
62  1 Y 1 A ARG 201 ? C ARG 201 
63  1 Y 1 A ASN 202 ? C ASN 202 
64  1 Y 1 A GLY 203 ? C GLY 203 
65  1 Y 1 A THR 277 ? C THR 277 
66  1 Y 1 A THR 278 ? C THR 278 
67  1 Y 1 B SER 1   ? D SER 1   
68  1 Y 1 B PRO 2   ? D PRO 2   
69  1 Y 1 B SER 3   ? D SER 3   
70  1 Y 1 B ALA 4   ? D ALA 4   
71  1 Y 1 B GLU 5   ? D GLU 5   
72  1 Y 1 B GLU 6   ? D GLU 6   
73  1 Y 1 B CYS 7   ? D CYS 7   
74  1 Y 1 B GLY 8   ? D GLY 8   
75  1 Y 1 B TYR 9   ? D TYR 9   
76  1 Y 1 B SER 10  ? D SER 10  
77  1 Y 1 B ASP 11  ? D ASP 11  
78  1 Y 1 B ARG 12  ? D ARG 12  
79  1 Y 1 B VAL 13  ? D VAL 13  
80  1 Y 1 B GLU 27  ? D GLU 27  
81  1 Y 1 B CYS 28  ? D CYS 28  
82  1 Y 1 B ALA 29  ? D ALA 29  
83  1 Y 1 B LYS 43  ? D LYS 43  
84  1 Y 1 B ASP 44  ? D ASP 44  
85  1 Y 1 B ASN 45  ? D ASN 45  
86  1 Y 1 B GLU 46  ? D GLU 46  
87  1 Y 1 B ALA 47  ? D ALA 47  
88  1 Y 1 B THR 48  ? D THR 48  
89  1 Y 1 B ALA 49  ? D ALA 49  
90  1 Y 1 B GLU 50  ? D GLU 50  
91  1 Y 1 B ARG 258 ? D ARG 258 
92  1 Y 1 B LEU 259 ? D LEU 259 
93  1 Y 1 B ALA 260 ? D ALA 260 
94  1 Y 1 B SER 261 ? D SER 261 
95  1 Y 1 B ASN 262 ? D ASN 262 
96  1 Y 1 B GLN 263 ? D GLN 263 
97  1 Y 1 C GLN 173 ? E GLN 173 
98  1 Y 1 C THR 174 ? E THR 174 
99  1 Y 1 C HIS 175 ? E HIS 175 
100 1 Y 1 C TYR 176 ? E TYR 176 
101 1 Y 1 C ARG 177 ? E ARG 177 
102 1 Y 1 C TYR 178 ? E TYR 178 
103 1 Y 1 C VAL 179 ? E VAL 179 
104 1 Y 1 C VAL 180 ? E VAL 180 
105 1 Y 1 C GLU 181 ? E GLU 181 
106 1 Y 1 C ASP 182 ? E ASP 182 
107 1 Y 1 C GLU 183 ? E GLU 183 
108 1 Y 1 C TYR 184 ? E TYR 184 
109 1 Y 1 C THR 185 ? E THR 185 
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.ncbi_tax_id          12071 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organism             'Coxsackievirus B1' 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'PARTICLE SELECTION'       ? ? ? 1 ? ? 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
