data_7X3F
# 
_entry.id   7X3F 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.360 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7X3F         pdb_00007x3f 10.2210/pdb7x3f/pdb 
WWPDB D_1300027916 ?            ?                   
EMDB  EMD-32986    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 9A3 (CVB1-A:9A3)' 
_pdbx_database_related.db_id          EMD-32986 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7X3F 
_pdbx_database_status.recvd_initial_deposition_date   2022-02-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zheng, Q.' 1 ? 
'Zhu, R.'   2 ? 
'Sun, H.'   3 ? 
'Cheng, T.' 4 ? 
'Li, S.'    5 ? 
'Xia, N.'   6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Host Microbe' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1934-6069 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            30 
_citation.language                  ? 
_citation.page_first                1279 
_citation.page_last                 1294.e6 
_citation.title                     
'Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.' 
_citation.year                      2022 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.chom.2022.08.001 
_citation.pdbx_database_id_PubMed   36002016 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zheng, Q.' 1  ? 
primary 'Zhu, R.'   2  ? 
primary 'Yin, Z.'   3  ? 
primary 'Xu, L.'    4  ? 
primary 'Sun, H.'   5  ? 
primary 'Yu, H.'    6  ? 
primary 'Wu, Y.'    7  ? 
primary 'Jiang, Y.' 8  ? 
primary 'Huang, Q.' 9  ? 
primary 'Huang, Y.' 10 ? 
primary 'Zhang, D.' 11 ? 
primary 'Liu, L.'   12 ? 
primary 'Yang, H.'  13 ? 
primary 'He, M.'    14 ? 
primary 'Zhou, Z.'  15 ? 
primary 'Jiang, Y.' 16 ? 
primary 'Chen, Z.'  17 ? 
primary 'Zhao, H.'  18 ? 
primary 'Que, Y.'   19 ? 
primary 'Kong, Z.'  20 ? 
primary 'Zhou, L.'  21 ? 
primary 'Li, T.'    22 ? 
primary 'Zhang, J.' 23 ? 
primary 'Luo, W.'   24 ? 
primary 'Gu, Y.'    25 ? 
primary 'Cheng, T.' 26 ? 
primary 'Li, S.'    27 ? 
primary 'Xia, N.'   28 ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7X3F 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         7X3F 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer nat '9A3 heavy chain'  13768.251 1 ?                                     ? ? ? 
2 polymer nat '9A3 light chain'  11472.680 1 ?                                     ? ? ? 
3 polymer nat 'Virion protein 1' 31207.117 1 ?                                     ? ? ? 
4 polymer nat VP2                29122.744 1 ?                                     ? ? ? 
5 polymer nat VP3                26328.764 1 3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48 ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'VP1, P1C,P1D' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVKLVESGGGLVQPGGSLSLSCAASGFTFTDYYMNWVRQPSGKALEWLGFLRNKANGYTTEYSASVKGRFTISRDNSQSI
LYLQMNALRAEDSATYYCARSRYYGGTYRYALDYWGQGTSVTVS
;
;EVKLVESGGGLVQPGGSLSLSCAASGFTFTDYYMNWVRQPSGKALEWLGFLRNKANGYTTEYSASVKGRFTISRDNSQSI
LYLQMNALRAEDSATYYCARSRYYGGTYRYALDYWGQGTSVTVS
;
H ? 
2 'polypeptide(L)' no no 
;ENVLTQSPPIMSASPGEKVTMTCRASSSVSSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGAGTKLELK
;
;ENVLTQSPPIMSASPGEKVTMTCRASSSVSSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGAGTKLELK
;
L ? 
3 'polypeptide(L)' no no 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
A ? 
4 'polypeptide(L)' no no 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
B ? 
5 'polypeptide(L)' no no 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   LYS n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  SER n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  ALA n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  THR n 
1 29  PHE n 
1 30  THR n 
1 31  ASP n 
1 32  TYR n 
1 33  TYR n 
1 34  MET n 
1 35  ASN n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  PRO n 
1 41  SER n 
1 42  GLY n 
1 43  LYS n 
1 44  ALA n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  LEU n 
1 49  GLY n 
1 50  PHE n 
1 51  LEU n 
1 52  ARG n 
1 53  ASN n 
1 54  LYS n 
1 55  ALA n 
1 56  ASN n 
1 57  GLY n 
1 58  TYR n 
1 59  THR n 
1 60  THR n 
1 61  GLU n 
1 62  TYR n 
1 63  SER n 
1 64  ALA n 
1 65  SER n 
1 66  VAL n 
1 67  LYS n 
1 68  GLY n 
1 69  ARG n 
1 70  PHE n 
1 71  THR n 
1 72  ILE n 
1 73  SER n 
1 74  ARG n 
1 75  ASP n 
1 76  ASN n 
1 77  SER n 
1 78  GLN n 
1 79  SER n 
1 80  ILE n 
1 81  LEU n 
1 82  TYR n 
1 83  LEU n 
1 84  GLN n 
1 85  MET n 
1 86  ASN n 
1 87  ALA n 
1 88  LEU n 
1 89  ARG n 
1 90  ALA n 
1 91  GLU n 
1 92  ASP n 
1 93  SER n 
1 94  ALA n 
1 95  THR n 
1 96  TYR n 
1 97  TYR n 
1 98  CYS n 
1 99  ALA n 
1 100 ARG n 
1 101 SER n 
1 102 ARG n 
1 103 TYR n 
1 104 TYR n 
1 105 GLY n 
1 106 GLY n 
1 107 THR n 
1 108 TYR n 
1 109 ARG n 
1 110 TYR n 
1 111 ALA n 
1 112 LEU n 
1 113 ASP n 
1 114 TYR n 
1 115 TRP n 
1 116 GLY n 
1 117 GLN n 
1 118 GLY n 
1 119 THR n 
1 120 SER n 
1 121 VAL n 
1 122 THR n 
1 123 VAL n 
1 124 SER n 
2 1   GLU n 
2 2   ASN n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   PRO n 
2 10  ILE n 
2 11  MET n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  PRO n 
2 16  GLY n 
2 17  GLU n 
2 18  LYS n 
2 19  VAL n 
2 20  THR n 
2 21  MET n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  SER n 
2 28  SER n 
2 29  VAL n 
2 30  SER n 
2 31  SER n 
2 32  SER n 
2 33  TYR n 
2 34  LEU n 
2 35  HIS n 
2 36  TRP n 
2 37  TYR n 
2 38  GLN n 
2 39  GLN n 
2 40  LYS n 
2 41  SER n 
2 42  GLY n 
2 43  ALA n 
2 44  SER n 
2 45  PRO n 
2 46  LYS n 
2 47  LEU n 
2 48  TRP n 
2 49  ILE n 
2 50  TYR n 
2 51  SER n 
2 52  THR n 
2 53  SER n 
2 54  ASN n 
2 55  LEU n 
2 56  ALA n 
2 57  SER n 
2 58  GLY n 
2 59  VAL n 
2 60  PRO n 
2 61  ALA n 
2 62  ARG n 
2 63  PHE n 
2 64  SER n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  SER n 
2 69  GLY n 
2 70  THR n 
2 71  SER n 
2 72  TYR n 
2 73  SER n 
2 74  LEU n 
2 75  THR n 
2 76  ILE n 
2 77  SER n 
2 78  SER n 
2 79  VAL n 
2 80  GLU n 
2 81  ALA n 
2 82  GLU n 
2 83  ASP n 
2 84  ALA n 
2 85  ALA n 
2 86  THR n 
2 87  TYR n 
2 88  TYR n 
2 89  CYS n 
2 90  GLN n 
2 91  GLN n 
2 92  PHE n 
2 93  SER n 
2 94  GLY n 
2 95  TYR n 
2 96  PRO n 
2 97  LEU n 
2 98  THR n 
2 99  PHE n 
2 100 GLY n 
2 101 ALA n 
2 102 GLY n 
2 103 THR n 
2 104 LYS n 
2 105 LEU n 
2 106 GLU n 
2 107 LEU n 
2 108 LYS n 
3 1   GLY n 
3 2   PRO n 
3 3   VAL n 
3 4   GLU n 
3 5   GLU n 
3 6   SER n 
3 7   VAL n 
3 8   ASP n 
3 9   ARG n 
3 10  ALA n 
3 11  VAL n 
3 12  ALA n 
3 13  ARG n 
3 14  VAL n 
3 15  ALA n 
3 16  ASP n 
3 17  THR n 
3 18  ILE n 
3 19  SER n 
3 20  SER n 
3 21  ARG n 
3 22  PRO n 
3 23  THR n 
3 24  ASN n 
3 25  SER n 
3 26  GLU n 
3 27  SER n 
3 28  ILE n 
3 29  PRO n 
3 30  ALA n 
3 31  LEU n 
3 32  THR n 
3 33  ALA n 
3 34  ALA n 
3 35  GLU n 
3 36  THR n 
3 37  GLY n 
3 38  HIS n 
3 39  THR n 
3 40  SER n 
3 41  GLN n 
3 42  VAL n 
3 43  VAL n 
3 44  PRO n 
3 45  SER n 
3 46  ASP n 
3 47  THR n 
3 48  MET n 
3 49  GLN n 
3 50  THR n 
3 51  ARG n 
3 52  HIS n 
3 53  VAL n 
3 54  LYS n 
3 55  ASN n 
3 56  TYR n 
3 57  HIS n 
3 58  SER n 
3 59  ARG n 
3 60  SER n 
3 61  GLU n 
3 62  SER n 
3 63  SER n 
3 64  ILE n 
3 65  GLU n 
3 66  ASN n 
3 67  PHE n 
3 68  LEU n 
3 69  CYS n 
3 70  ARG n 
3 71  SER n 
3 72  ALA n 
3 73  CYS n 
3 74  VAL n 
3 75  TYR n 
3 76  TYR n 
3 77  ALA n 
3 78  THR n 
3 79  TYR n 
3 80  THR n 
3 81  ASN n 
3 82  ASN n 
3 83  SER n 
3 84  LYS n 
3 85  LYS n 
3 86  GLY n 
3 87  PHE n 
3 88  ALA n 
3 89  GLU n 
3 90  TRP n 
3 91  VAL n 
3 92  ILE n 
3 93  ASN n 
3 94  THR n 
3 95  ARG n 
3 96  GLN n 
3 97  VAL n 
3 98  ALA n 
3 99  GLN n 
3 100 LEU n 
3 101 ARG n 
3 102 ARG n 
3 103 LYS n 
3 104 LEU n 
3 105 GLU n 
3 106 LEU n 
3 107 PHE n 
3 108 THR n 
3 109 TYR n 
3 110 LEU n 
3 111 ARG n 
3 112 PHE n 
3 113 ASP n 
3 114 LEU n 
3 115 GLU n 
3 116 LEU n 
3 117 THR n 
3 118 PHE n 
3 119 VAL n 
3 120 ILE n 
3 121 THR n 
3 122 SER n 
3 123 ALA n 
3 124 GLN n 
3 125 GLN n 
3 126 PRO n 
3 127 SER n 
3 128 THR n 
3 129 ALA n 
3 130 SER n 
3 131 SER n 
3 132 VAL n 
3 133 ASP n 
3 134 ALA n 
3 135 PRO n 
3 136 VAL n 
3 137 GLN n 
3 138 THR n 
3 139 HIS n 
3 140 GLN n 
3 141 ILE n 
3 142 MET n 
3 143 TYR n 
3 144 VAL n 
3 145 PRO n 
3 146 PRO n 
3 147 GLY n 
3 148 GLY n 
3 149 PRO n 
3 150 VAL n 
3 151 PRO n 
3 152 THR n 
3 153 LYS n 
3 154 VAL n 
3 155 LYS n 
3 156 ASP n 
3 157 TYR n 
3 158 ALA n 
3 159 TRP n 
3 160 GLN n 
3 161 THR n 
3 162 SER n 
3 163 THR n 
3 164 ASN n 
3 165 PRO n 
3 166 SER n 
3 167 VAL n 
3 168 PHE n 
3 169 TRP n 
3 170 THR n 
3 171 GLU n 
3 172 GLY n 
3 173 ASN n 
3 174 ALA n 
3 175 PRO n 
3 176 PRO n 
3 177 ARG n 
3 178 MET n 
3 179 SER n 
3 180 ILE n 
3 181 PRO n 
3 182 PHE n 
3 183 ILE n 
3 184 SER n 
3 185 ILE n 
3 186 GLY n 
3 187 ASN n 
3 188 ALA n 
3 189 TYR n 
3 190 SER n 
3 191 CYS n 
3 192 PHE n 
3 193 TYR n 
3 194 ASP n 
3 195 GLY n 
3 196 TRP n 
3 197 THR n 
3 198 GLN n 
3 199 PHE n 
3 200 SER n 
3 201 ARG n 
3 202 ASN n 
3 203 GLY n 
3 204 VAL n 
3 205 TYR n 
3 206 GLY n 
3 207 ILE n 
3 208 ASN n 
3 209 THR n 
3 210 LEU n 
3 211 ASN n 
3 212 ASN n 
3 213 MET n 
3 214 GLY n 
3 215 THR n 
3 216 LEU n 
3 217 TYR n 
3 218 MET n 
3 219 ARG n 
3 220 HIS n 
3 221 VAL n 
3 222 ASN n 
3 223 GLU n 
3 224 ALA n 
3 225 GLY n 
3 226 GLN n 
3 227 GLY n 
3 228 PRO n 
3 229 ILE n 
3 230 LYS n 
3 231 SER n 
3 232 THR n 
3 233 VAL n 
3 234 ARG n 
3 235 ILE n 
3 236 TYR n 
3 237 PHE n 
3 238 LYS n 
3 239 PRO n 
3 240 LYS n 
3 241 HIS n 
3 242 VAL n 
3 243 LYS n 
3 244 ALA n 
3 245 TRP n 
3 246 VAL n 
3 247 PRO n 
3 248 ARG n 
3 249 PRO n 
3 250 PRO n 
3 251 ARG n 
3 252 LEU n 
3 253 CYS n 
3 254 GLN n 
3 255 TYR n 
3 256 GLU n 
3 257 LYS n 
3 258 GLN n 
3 259 LYS n 
3 260 ASN n 
3 261 VAL n 
3 262 ASN n 
3 263 PHE n 
3 264 SER n 
3 265 PRO n 
3 266 ILE n 
3 267 GLY n 
3 268 VAL n 
3 269 THR n 
3 270 THR n 
3 271 SER n 
3 272 ARG n 
3 273 THR n 
3 274 ASP n 
3 275 ILE n 
3 276 ILE n 
3 277 THR n 
3 278 THR n 
4 1   SER n 
4 2   PRO n 
4 3   SER n 
4 4   ALA n 
4 5   GLU n 
4 6   GLU n 
4 7   CYS n 
4 8   GLY n 
4 9   TYR n 
4 10  SER n 
4 11  ASP n 
4 12  ARG n 
4 13  VAL n 
4 14  ARG n 
4 15  SER n 
4 16  ILE n 
4 17  THR n 
4 18  LEU n 
4 19  GLY n 
4 20  ASN n 
4 21  SER n 
4 22  THR n 
4 23  ILE n 
4 24  THR n 
4 25  THR n 
4 26  GLN n 
4 27  GLU n 
4 28  CYS n 
4 29  ALA n 
4 30  ASN n 
4 31  VAL n 
4 32  VAL n 
4 33  VAL n 
4 34  GLY n 
4 35  TYR n 
4 36  GLY n 
4 37  VAL n 
4 38  TRP n 
4 39  PRO n 
4 40  GLU n 
4 41  TYR n 
4 42  LEU n 
4 43  LYS n 
4 44  ASP n 
4 45  ASN n 
4 46  GLU n 
4 47  ALA n 
4 48  THR n 
4 49  ALA n 
4 50  GLU n 
4 51  ASP n 
4 52  GLN n 
4 53  PRO n 
4 54  THR n 
4 55  GLN n 
4 56  PRO n 
4 57  ASP n 
4 58  VAL n 
4 59  ALA n 
4 60  THR n 
4 61  CYS n 
4 62  ARG n 
4 63  PHE n 
4 64  TYR n 
4 65  THR n 
4 66  LEU n 
4 67  GLU n 
4 68  SER n 
4 69  VAL n 
4 70  GLN n 
4 71  TRP n 
4 72  MET n 
4 73  LYS n 
4 74  ASN n 
4 75  SER n 
4 76  ALA n 
4 77  GLY n 
4 78  TRP n 
4 79  TRP n 
4 80  TRP n 
4 81  LYS n 
4 82  LEU n 
4 83  PRO n 
4 84  ASP n 
4 85  ALA n 
4 86  LEU n 
4 87  SER n 
4 88  GLN n 
4 89  MET n 
4 90  GLY n 
4 91  LEU n 
4 92  PHE n 
4 93  GLY n 
4 94  GLN n 
4 95  ASN n 
4 96  MET n 
4 97  GLN n 
4 98  TYR n 
4 99  HIS n 
4 100 TYR n 
4 101 LEU n 
4 102 GLY n 
4 103 ARG n 
4 104 THR n 
4 105 GLY n 
4 106 TYR n 
4 107 THR n 
4 108 ILE n 
4 109 HIS n 
4 110 VAL n 
4 111 GLN n 
4 112 CYS n 
4 113 ASN n 
4 114 ALA n 
4 115 SER n 
4 116 LYS n 
4 117 PHE n 
4 118 HIS n 
4 119 GLN n 
4 120 GLY n 
4 121 CYS n 
4 122 LEU n 
4 123 LEU n 
4 124 VAL n 
4 125 VAL n 
4 126 CYS n 
4 127 VAL n 
4 128 PRO n 
4 129 GLU n 
4 130 ALA n 
4 131 GLU n 
4 132 MET n 
4 133 GLY n 
4 134 CYS n 
4 135 SER n 
4 136 ASN n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 THR n 
4 141 PRO n 
4 142 GLU n 
4 143 PHE n 
4 144 SER n 
4 145 GLU n 
4 146 LEU n 
4 147 SER n 
4 148 GLY n 
4 149 GLY n 
4 150 ASP n 
4 151 SER n 
4 152 ALA n 
4 153 ARG n 
4 154 MET n 
4 155 PHE n 
4 156 THR n 
4 157 ASP n 
4 158 THR n 
4 159 GLN n 
4 160 VAL n 
4 161 GLY n 
4 162 GLU n 
4 163 SER n 
4 164 ASN n 
4 165 ALA n 
4 166 LYS n 
4 167 LYS n 
4 168 VAL n 
4 169 GLN n 
4 170 THR n 
4 171 ALA n 
4 172 VAL n 
4 173 TRP n 
4 174 ASN n 
4 175 ALA n 
4 176 GLY n 
4 177 MET n 
4 178 GLY n 
4 179 VAL n 
4 180 GLY n 
4 181 VAL n 
4 182 GLY n 
4 183 ASN n 
4 184 LEU n 
4 185 THR n 
4 186 ILE n 
4 187 PHE n 
4 188 PRO n 
4 189 HIS n 
4 190 GLN n 
4 191 TRP n 
4 192 ILE n 
4 193 ASN n 
4 194 LEU n 
4 195 ARG n 
4 196 THR n 
4 197 ASN n 
4 198 ASN n 
4 199 SER n 
4 200 ALA n 
4 201 THR n 
4 202 LEU n 
4 203 VAL n 
4 204 MET n 
4 205 PRO n 
4 206 TYR n 
4 207 ILE n 
4 208 ASN n 
4 209 SER n 
4 210 VAL n 
4 211 PRO n 
4 212 MET n 
4 213 ASP n 
4 214 ASN n 
4 215 MET n 
4 216 PHE n 
4 217 ARG n 
4 218 HIS n 
4 219 ASN n 
4 220 ASN n 
4 221 LEU n 
4 222 THR n 
4 223 LEU n 
4 224 MET n 
4 225 ILE n 
4 226 ILE n 
4 227 PRO n 
4 228 PHE n 
4 229 VAL n 
4 230 PRO n 
4 231 LEU n 
4 232 ASN n 
4 233 TYR n 
4 234 SER n 
4 235 GLU n 
4 236 GLY n 
4 237 SER n 
4 238 SER n 
4 239 PRO n 
4 240 TYR n 
4 241 VAL n 
4 242 PRO n 
4 243 ILE n 
4 244 THR n 
4 245 VAL n 
4 246 THR n 
4 247 ILE n 
4 248 ALA n 
4 249 PRO n 
4 250 MET n 
4 251 CYS n 
4 252 ALA n 
4 253 GLU n 
4 254 TYR n 
4 255 ASN n 
4 256 GLY n 
4 257 LEU n 
4 258 ARG n 
4 259 LEU n 
4 260 ALA n 
4 261 SER n 
4 262 ASN n 
4 263 GLN n 
5 1   GLY n 
5 2   LEU n 
5 3   PRO n 
5 4   VAL n 
5 5   MET n 
5 6   THR n 
5 7   THR n 
5 8   PRO n 
5 9   GLY n 
5 10  SER n 
5 11  THR n 
5 12  GLN n 
5 13  PHE n 
5 14  LEU n 
5 15  THR n 
5 16  SER n 
5 17  ASP n 
5 18  ASP n 
5 19  PHE n 
5 20  GLN n 
5 21  SER n 
5 22  PRO n 
5 23  SER n 
5 24  ALA n 
5 25  MET n 
5 26  PRO n 
5 27  GLN n 
5 28  PHE n 
5 29  ASP n 
5 30  VAL n 
5 31  THR n 
5 32  PRO n 
5 33  GLU n 
5 34  MET n 
5 35  GLN n 
5 36  ILE n 
5 37  PRO n 
5 38  GLY n 
5 39  ARG n 
5 40  VAL n 
5 41  ASN n 
5 42  ASN n 
5 43  LEU n 
5 44  MET n 
5 45  GLU n 
5 46  ILE n 
5 47  ALA n 
5 48  GLU n 
5 49  VAL n 
5 50  ASP n 
5 51  SER n 
5 52  VAL n 
5 53  VAL n 
5 54  PRO n 
5 55  VAL n 
5 56  ASN n 
5 57  ASN n 
5 58  THR n 
5 59  GLU n 
5 60  ASP n 
5 61  ASN n 
5 62  VAL n 
5 63  SER n 
5 64  SER n 
5 65  LEU n 
5 66  LYS n 
5 67  ALA n 
5 68  TYR n 
5 69  GLN n 
5 70  ILE n 
5 71  PRO n 
5 72  VAL n 
5 73  GLN n 
5 74  SER n 
5 75  ASN n 
5 76  SER n 
5 77  ASP n 
5 78  ASN n 
5 79  GLY n 
5 80  LYS n 
5 81  GLN n 
5 82  VAL n 
5 83  PHE n 
5 84  GLY n 
5 85  PHE n 
5 86  PRO n 
5 87  LEU n 
5 88  GLN n 
5 89  PRO n 
5 90  GLY n 
5 91  ALA n 
5 92  ASN n 
5 93  ASN n 
5 94  VAL n 
5 95  LEU n 
5 96  ASN n 
5 97  ARG n 
5 98  THR n 
5 99  LEU n 
5 100 LEU n 
5 101 GLY n 
5 102 GLU n 
5 103 ILE n 
5 104 LEU n 
5 105 ASN n 
5 106 TYR n 
5 107 TYR n 
5 108 THR n 
5 109 HIS n 
5 110 TRP n 
5 111 SER n 
5 112 GLY n 
5 113 SER n 
5 114 ILE n 
5 115 LYS n 
5 116 LEU n 
5 117 THR n 
5 118 PHE n 
5 119 MET n 
5 120 PHE n 
5 121 CYS n 
5 122 GLY n 
5 123 SER n 
5 124 ALA n 
5 125 MET n 
5 126 ALA n 
5 127 THR n 
5 128 GLY n 
5 129 LYS n 
5 130 PHE n 
5 131 LEU n 
5 132 LEU n 
5 133 ALA n 
5 134 TYR n 
5 135 SER n 
5 136 PRO n 
5 137 PRO n 
5 138 GLY n 
5 139 ALA n 
5 140 GLY n 
5 141 VAL n 
5 142 PRO n 
5 143 LYS n 
5 144 ASN n 
5 145 ARG n 
5 146 LYS n 
5 147 ASP n 
5 148 ALA n 
5 149 MET n 
5 150 LEU n 
5 151 GLY n 
5 152 THR n 
5 153 HIS n 
5 154 VAL n 
5 155 ILE n 
5 156 TRP n 
5 157 ASP n 
5 158 VAL n 
5 159 GLY n 
5 160 LEU n 
5 161 GLN n 
5 162 SER n 
5 163 SER n 
5 164 CYS n 
5 165 VAL n 
5 166 LEU n 
5 167 CYS n 
5 168 VAL n 
5 169 PRO n 
5 170 TRP n 
5 171 ILE n 
5 172 SER n 
5 173 GLN n 
5 174 THR n 
5 175 HIS n 
5 176 TYR n 
5 177 ARG n 
5 178 TYR n 
5 179 VAL n 
5 180 VAL n 
5 181 GLU n 
5 182 ASP n 
5 183 GLU n 
5 184 TYR n 
5 185 THR n 
5 186 ALA n 
5 187 ALA n 
5 188 GLY n 
5 189 TYR n 
5 190 VAL n 
5 191 THR n 
5 192 CYS n 
5 193 TRP n 
5 194 TYR n 
5 195 GLN n 
5 196 THR n 
5 197 ASN n 
5 198 ILE n 
5 199 VAL n 
5 200 VAL n 
5 201 PRO n 
5 202 ALA n 
5 203 ASP n 
5 204 VAL n 
5 205 GLN n 
5 206 SER n 
5 207 SER n 
5 208 CYS n 
5 209 ASP n 
5 210 ILE n 
5 211 LEU n 
5 212 CYS n 
5 213 PHE n 
5 214 VAL n 
5 215 SER n 
5 216 ALA n 
5 217 CYS n 
5 218 ASN n 
5 219 ASP n 
5 220 PHE n 
5 221 SER n 
5 222 VAL n 
5 223 ARG n 
5 224 MET n 
5 225 LEU n 
5 226 LYS n 
5 227 ASP n 
5 228 THR n 
5 229 PRO n 
5 230 PHE n 
5 231 ILE n 
5 232 ARG n 
5 233 GLN n 
5 234 ASP n 
5 235 THR n 
5 236 PHE n 
5 237 TYR n 
5 238 GLN n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 124 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 108 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 1 278 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 263 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 1 238 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7X3F             7X3F       ? 1 ? 1   
2 PDB 7X3F             7X3F       ? 2 ? 1   
3 UNP W8GTF7_9ENTO     W8GTF7     ? 3 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSEKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
1   
4 UNP A0A2S0RQC2_9ENTO A0A2S0RQC2 ? 4 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
70  
5 UNP L7UV52_9ENTO     L7UV52     ? 5 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7X3F H 1 ? 124 ? 7X3F       1   ? 124 ? 1 124 
2 2 7X3F L 1 ? 108 ? 7X3F       1   ? 108 ? 1 108 
3 3 7X3F A 1 ? 278 ? W8GTF7     1   ? 278 ? 1 278 
4 4 7X3F B 1 ? 263 ? A0A2S0RQC2 70  ? 332 ? 1 263 
5 5 7X3F C 1 ? 238 ? L7UV52     333 ? 570 ? 1 238 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             7X3F 
_struct_ref_seq_dif.mon_id                       LYS 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      84 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   W8GTF7 
_struct_ref_seq_dif.db_mon_id                    GLU 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          84 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            84 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7X3F 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7X3F 
_struct.title                        'Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 9A3 (CVB1-A:9A3)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7X3F 
_struct_keywords.text            'Coxsackievirus B1, Neutralizing antibody, Cryo-EM, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 28  ? TYR A 32  ? THR H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2  AA2 ASN A 53  ? GLY A 57  ? ASN H 53  GLY H 57  5 ? 5 
HELX_P HELX_P3  AA3 ARG A 89  ? SER A 93  ? ARG H 89  SER H 93  5 ? 5 
HELX_P HELX_P4  AA4 SER C 63  ? CYS C 69  ? SER A 63  CYS A 69  1 ? 7 
HELX_P HELX_P5  AA5 VAL C 97  ? GLU C 105 ? VAL A 97  GLU A 105 1 ? 9 
HELX_P HELX_P6  AA6 ASP C 156 ? THR C 161 ? ASP A 156 THR A 161 5 ? 6 
HELX_P HELX_P7  AA7 LEU D 82  ? LEU D 86  ? LEU B 82  LEU B 86  1 ? 5 
HELX_P HELX_P8  AA8 LEU D 91  ? HIS D 99  ? LEU B 91  HIS B 99  1 ? 9 
HELX_P HELX_P9  AA9 GLU D 142 ? SER D 147 ? GLU B 142 SER B 147 1 ? 6 
HELX_P HELX_P10 AB1 ALA D 171 ? ALA D 175 ? ALA B 171 ALA B 175 5 ? 5 
HELX_P HELX_P11 AB2 VAL D 181 ? PHE D 187 ? VAL B 181 PHE B 187 5 ? 7 
HELX_P HELX_P12 AB3 LEU E 43  ? GLU E 48  ? LEU C 43  GLU C 48  1 ? 6 
HELX_P HELX_P13 AB4 THR E 98  ? LEU E 104 ? THR C 98  LEU C 104 1 ? 7 
HELX_P HELX_P14 AB5 ARG E 145 ? LEU E 150 ? ARG C 145 LEU C 150 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22 SG ? ? ? 1_555 A CYS 98 SG ? ? H CYS 22 H CYS 98 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf2 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 89 SG ? ? L CYS 23 L CYS 89 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7  B . ? SER 7  L PRO 8  B ? PRO 8  L 1 -2.40 
2 TYR 95 B . ? TYR 95 L PRO 96 B ? PRO 96 L 1 3.78  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 6 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
AA9 ? 9 ? 
AB1 ? 5 ? 
AB2 ? 6 ? 
AB3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 5 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 2 4 ? anti-parallel 
AA6 2 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 6 ? parallel      
AA9 2 9 ? anti-parallel 
AA9 3 8 ? anti-parallel 
AA9 4 8 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 5 7 ? anti-parallel 
AA9 5 8 ? anti-parallel 
AA9 5 9 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB2 1 5 ? anti-parallel 
AB2 2 5 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 3 5 ? anti-parallel 
AB2 3 6 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 3   ? SER A 7   ? LYS H 3   SER H 7   
AA1 2 LEU A 18  ? SER A 25  ? LEU H 18  SER H 25  
AA1 3 ILE A 80  ? MET A 85  ? ILE H 80  MET H 85  
AA1 4 PHE A 70  ? ARG A 74  ? PHE H 70  ARG H 74  
AA2 1 LEU A 11  ? VAL A 12  ? LEU H 11  VAL H 12  
AA2 2 THR A 119 ? VAL A 123 ? THR H 119 VAL H 123 
AA2 3 ALA A 94  ? TYR A 96  ? ALA H 94  TYR H 96  
AA2 4 VAL A 37  ? GLN A 39  ? VAL H 37  GLN H 39  
AA2 5 GLU A 46  ? TRP A 47  ? GLU H 46  TRP H 47  
AA3 1 GLY A 49  ? LEU A 51  ? GLY H 49  LEU H 51  
AA3 2 THR A 60  ? TYR A 62  ? THR H 60  TYR H 62  
AA4 1 LEU B 4   ? SER B 7   ? LEU L 4   SER L 7   
AA4 2 VAL B 19  ? ALA B 25  ? VAL L 19  ALA L 25  
AA4 3 SER B 71  ? ILE B 76  ? SER L 71  ILE L 76  
AA4 4 PHE B 63  ? SER B 68  ? PHE L 63  SER L 68  
AA5 1 ILE B 10  ? ALA B 13  ? ILE L 10  ALA L 13  
AA5 2 THR B 103 ? LEU B 107 ? THR L 103 LEU L 107 
AA5 3 THR B 86  ? GLN B 90  ? THR L 86  GLN L 90  
AA5 4 HIS B 35  ? GLN B 39  ? HIS L 35  GLN L 39  
AA5 5 LYS B 46  ? TYR B 50  ? LYS L 46  TYR L 50  
AA5 6 ASN B 54  ? LEU B 55  ? ASN L 54  LEU L 55  
AA6 1 ALA C 72  ? THR C 80  ? ALA A 72  THR A 80  
AA6 2 PHE C 107 ? GLN C 124 ? PHE A 107 GLN A 124 
AA6 3 ARG C 177 ? ILE C 180 ? ARG A 177 ILE A 180 
AA6 4 TYR C 189 ? SER C 190 ? TYR A 189 SER A 190 
AA6 5 ILE C 229 ? PRO C 247 ? ILE A 229 PRO A 247 
AA6 6 ARG E 39  ? VAL E 40  ? ARG C 39  VAL C 40  
AA7 1 TRP C 90  ? VAL C 91  ? TRP A 90  VAL A 91  
AA7 2 THR C 215 ? HIS C 220 ? THR A 215 HIS A 220 
AA7 3 THR C 138 ? VAL C 144 ? THR A 138 VAL A 144 
AA7 4 SER C 166 ? THR C 170 ? SER A 166 THR A 170 
AA8 1 THR D 17  ? LEU D 18  ? THR B 17  LEU B 18  
AA8 2 SER D 21  ? THR D 22  ? SER B 21  THR B 22  
AA9 1 VAL D 32  ? VAL D 33  ? VAL B 32  VAL B 33  
AA9 2 PRO D 53  ? THR D 54  ? PRO B 53  THR B 54  
AA9 3 TYR D 64  ? THR D 65  ? TYR B 64  THR B 65  
AA9 4 VAL D 69  ? TRP D 71  ? VAL B 69  TRP B 71  
AA9 5 LEU D 101 ? CYS D 112 ? LEU B 101 CYS B 112 
AA9 6 SER D 199 ? MET D 204 ? SER B 199 MET B 204 
AA9 7 ASP D 213 ? ASN D 214 ? ASP B 213 ASN B 214 
AA9 8 VAL D 241 ? ILE D 247 ? VAL B 241 ILE B 247 
AA9 9 MET D 250 ? ASN D 255 ? MET B 250 ASN B 255 
AB1 1 ARG D 153 ? MET D 154 ? ARG B 153 MET B 154 
AB1 2 TRP D 78  ? LYS D 81  ? TRP B 78  LYS B 81  
AB1 3 LEU D 221 ? ASN D 232 ? LEU B 221 ASN B 232 
AB1 4 GLN D 119 ? PRO D 128 ? GLN B 119 PRO B 128 
AB1 5 HIS D 189 ? ASN D 193 ? HIS B 189 ASN B 193 
AB2 1 SER E 51  ? VAL E 52  ? SER C 51  VAL C 52  
AB2 2 ILE E 70  ? VAL E 72  ? ILE C 70  VAL C 72  
AB2 3 TYR E 107 ? CYS E 121 ? TYR C 107 CYS C 121 
AB2 4 VAL E 165 ? ILE E 171 ? VAL C 165 ILE C 171 
AB2 5 CYS E 208 ? VAL E 214 ? CYS C 208 VAL C 214 
AB2 6 SER E 221 ? LEU E 225 ? SER C 221 LEU C 225 
AB3 1 GLN E 81  ? PHE E 83  ? GLN C 81  PHE C 83  
AB3 2 CYS E 192 ? TYR E 194 ? CYS C 192 TYR C 194 
AB3 3 LYS E 129 ? LEU E 132 ? LYS C 129 LEU C 132 
AB3 4 ILE E 155 ? ASP E 157 ? ILE C 155 ASP C 157 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O SER A 21  ? O SER H 21  
AA1 2 3 N CYS A 22  ? N CYS H 22  O LEU A 81  ? O LEU H 81  
AA1 3 4 O GLN A 84  ? O GLN H 84  N THR A 71  ? N THR H 71  
AA2 1 2 N VAL A 12  ? N VAL H 12  O THR A 122 ? O THR H 122 
AA2 2 3 O THR A 119 ? O THR H 119 N TYR A 96  ? N TYR H 96  
AA2 3 4 O THR A 95  ? O THR H 95  N GLN A 39  ? N GLN H 39  
AA2 4 5 N ARG A 38  ? N ARG H 38  O GLU A 46  ? O GLU H 46  
AA3 1 2 N PHE A 50  ? N PHE H 50  O GLU A 61  ? O GLU H 61  
AA4 1 2 N THR B 5   ? N THR L 5   O ARG B 24  ? O ARG L 24  
AA4 2 3 N VAL B 19  ? N VAL L 19  O ILE B 76  ? O ILE L 76  
AA4 3 4 O SER B 73  ? O SER L 73  N SER B 66  ? N SER L 66  
AA5 1 2 N MET B 11  ? N MET L 11  O LYS B 104 ? O LYS L 104 
AA5 2 3 O THR B 103 ? O THR L 103 N TYR B 87  ? N TYR L 87  
AA5 3 4 O THR B 86  ? O THR L 86  N GLN B 39  ? N GLN L 39  
AA5 4 5 N TRP B 36  ? N TRP L 36  O ILE B 49  ? O ILE L 49  
AA5 5 6 N TYR B 50  ? N TYR L 50  O ASN B 54  ? O ASN L 54  
AA6 1 5 N TYR C 79  ? N TYR A 79  O SER C 231 ? O SER A 231 
AA6 2 3 N LEU C 116 ? N LEU A 116 O MET C 178 ? O MET A 178 
AA6 2 4 N LEU C 110 ? N LEU A 110 O TYR C 189 ? O TYR A 189 
AA6 2 5 N ASP C 113 ? N ASP A 113 O LYS C 240 ? O LYS A 240 
AA6 5 6 N ALA C 244 ? N ALA A 244 O VAL E 40  ? O VAL C 40  
AA7 1 2 N TRP C 90  ? N TRP A 90  O LEU C 216 ? O LEU A 216 
AA7 2 3 O ARG C 219 ? O ARG A 219 N GLN C 140 ? N GLN A 140 
AA7 3 4 N HIS C 139 ? N HIS A 139 O TRP C 169 ? O TRP A 169 
AA8 1 2 N LEU D 18  ? N LEU B 18  O SER D 21  ? O SER B 21  
AA9 1 6 N VAL D 32  ? N VAL B 32  O THR D 201 ? O THR B 201 
AA9 2 9 N THR D 54  ? N THR B 54  O TYR D 254 ? O TYR B 254 
AA9 3 8 N TYR D 64  ? N TYR B 64  O ILE D 247 ? O ILE B 247 
AA9 4 8 N VAL D 69  ? N VAL B 69  O ILE D 243 ? O ILE B 243 
AA9 5 6 N VAL D 110 ? N VAL B 110 O ALA D 200 ? O ALA B 200 
AA9 5 7 N GLY D 102 ? N GLY B 102 O ASP D 213 ? O ASP B 213 
AA9 5 8 N HIS D 109 ? N HIS B 109 O THR D 246 ? O THR B 246 
AA9 5 9 N GLY D 105 ? N GLY B 105 O MET D 250 ? O MET B 250 
AB1 1 2 O ARG D 153 ? O ARG B 153 N TRP D 79  ? N TRP B 79  
AB1 2 3 N TRP D 78  ? N TRP B 78  O ILE D 225 ? O ILE B 225 
AB1 3 4 O THR D 222 ? O THR B 222 N VAL D 127 ? N VAL B 127 
AB1 4 5 N LEU D 122 ? N LEU B 122 O ILE D 192 ? O ILE B 192 
AB2 1 5 N SER E 51  ? N SER C 51  O VAL E 214 ? O VAL C 214 
AB2 2 5 N VAL E 72  ? N VAL C 72  O CYS E 208 ? O CYS C 208 
AB2 3 4 N GLY E 112 ? N GLY C 112 O TRP E 170 ? O TRP C 170 
AB2 3 5 N THR E 117 ? N THR C 117 O PHE E 213 ? O PHE C 213 
AB2 3 6 N HIS E 109 ? N HIS C 109 O ARG E 223 ? O ARG C 223 
AB3 1 2 N VAL E 82  ? N VAL C 82  O CYS E 192 ? O CYS C 192 
AB3 2 3 O TRP E 193 ? O TRP C 193 N LEU E 131 ? N LEU C 131 
AB3 3 4 N PHE E 130 ? N PHE C 130 O TRP E 156 ? O TRP C 156 
# 
_atom_sites.entry_id                    7X3F 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLU A 1 1   ? 298.938 370.537 476.650 1.00 140.23 ? 1   GLU H N   1 
ATOM 2    C CA  . GLU A 1 1   ? 297.854 370.030 477.480 1.00 140.23 ? 1   GLU H CA  1 
ATOM 3    C C   . GLU A 1 1   ? 296.505 370.530 476.983 1.00 140.23 ? 1   GLU H C   1 
ATOM 4    O O   . GLU A 1 1   ? 296.412 371.587 476.364 1.00 140.23 ? 1   GLU H O   1 
ATOM 5    C CB  . GLU A 1 1   ? 298.087 370.419 478.948 1.00 140.23 ? 1   GLU H CB  1 
ATOM 6    C CG  . GLU A 1 1   ? 298.254 371.917 479.224 1.00 140.23 ? 1   GLU H CG  1 
ATOM 7    C CD  . GLU A 1 1   ? 296.944 372.659 479.444 1.00 140.23 ? 1   GLU H CD  1 
ATOM 8    O OE1 . GLU A 1 1   ? 296.954 373.907 479.435 1.00 140.23 ? 1   GLU H OE1 1 
ATOM 9    O OE2 . GLU A 1 1   ? 295.909 371.995 479.647 1.00 140.23 ? 1   GLU H OE2 1 
ATOM 10   N N   . VAL A 1 2   ? 295.461 369.764 477.262 1.00 133.36 ? 2   VAL H N   1 
ATOM 11   C CA  . VAL A 1 2   ? 294.106 370.130 476.881 1.00 133.36 ? 2   VAL H CA  1 
ATOM 12   C C   . VAL A 1 2   ? 293.477 370.921 478.016 1.00 133.36 ? 2   VAL H C   1 
ATOM 13   O O   . VAL A 1 2   ? 293.379 370.432 479.147 1.00 133.36 ? 2   VAL H O   1 
ATOM 14   C CB  . VAL A 1 2   ? 293.274 368.881 476.555 1.00 133.36 ? 2   VAL H CB  1 
ATOM 15   C CG1 . VAL A 1 2   ? 292.002 369.272 475.845 1.00 133.36 ? 2   VAL H CG1 1 
ATOM 16   C CG2 . VAL A 1 2   ? 294.085 367.920 475.713 1.00 133.36 ? 2   VAL H CG2 1 
ATOM 17   N N   . LYS A 1 3   ? 293.049 372.143 477.721 1.00 135.39 ? 3   LYS H N   1 
ATOM 18   C CA  . LYS A 1 3   ? 292.463 373.015 478.733 1.00 135.39 ? 3   LYS H CA  1 
ATOM 19   C C   . LYS A 1 3   ? 291.128 373.517 478.210 1.00 135.39 ? 3   LYS H C   1 
ATOM 20   O O   . LYS A 1 3   ? 291.084 374.292 477.249 1.00 135.39 ? 3   LYS H O   1 
ATOM 21   C CB  . LYS A 1 3   ? 293.398 374.176 479.070 1.00 135.39 ? 3   LYS H CB  1 
ATOM 22   C CG  . LYS A 1 3   ? 292.759 375.284 479.896 1.00 135.39 ? 3   LYS H CG  1 
ATOM 23   C CD  . LYS A 1 3   ? 292.382 374.815 481.296 1.00 135.39 ? 3   LYS H CD  1 
ATOM 24   C CE  . LYS A 1 3   ? 293.578 374.257 482.053 1.00 135.39 ? 3   LYS H CE  1 
ATOM 25   N NZ  . LYS A 1 3   ? 293.152 373.343 483.147 1.00 135.39 ? 3   LYS H NZ  1 
ATOM 26   N N   . LEU A 1 4   ? 290.045 373.068 478.835 1.00 129.52 ? 4   LEU H N   1 
ATOM 27   C CA  . LEU A 1 4   ? 288.689 373.443 478.456 1.00 129.52 ? 4   LEU H CA  1 
ATOM 28   C C   . LEU A 1 4   ? 288.040 374.167 479.621 1.00 129.52 ? 4   LEU H C   1 
ATOM 29   O O   . LEU A 1 4   ? 287.915 373.603 480.712 1.00 129.52 ? 4   LEU H O   1 
ATOM 30   C CB  . LEU A 1 4   ? 287.867 372.213 478.076 1.00 129.52 ? 4   LEU H CB  1 
ATOM 31   C CG  . LEU A 1 4   ? 288.374 371.395 476.899 1.00 129.52 ? 4   LEU H CG  1 
ATOM 32   C CD1 . LEU A 1 4   ? 287.931 369.969 477.046 1.00 129.52 ? 4   LEU H CD1 1 
ATOM 33   C CD2 . LEU A 1 4   ? 287.826 371.973 475.628 1.00 129.52 ? 4   LEU H CD2 1 
ATOM 34   N N   . VAL A 1 5   ? 287.634 375.411 479.397 1.00 133.11 ? 5   VAL H N   1 
ATOM 35   C CA  . VAL A 1 5   ? 286.860 376.170 480.369 1.00 133.11 ? 5   VAL H CA  1 
ATOM 36   C C   . VAL A 1 5   ? 285.521 376.500 479.732 1.00 133.11 ? 5   VAL H C   1 
ATOM 37   O O   . VAL A 1 5   ? 285.397 376.514 478.501 1.00 133.11 ? 5   VAL H O   1 
ATOM 38   C CB  . VAL A 1 5   ? 287.592 377.442 480.834 1.00 133.11 ? 5   VAL H CB  1 
ATOM 39   C CG1 . VAL A 1 5   ? 288.997 377.106 481.295 1.00 133.11 ? 5   VAL H CG1 1 
ATOM 40   C CG2 . VAL A 1 5   ? 287.644 378.487 479.734 1.00 133.11 ? 5   VAL H CG2 1 
ATOM 41   N N   . GLU A 1 6   ? 284.507 376.700 480.562 1.00 132.80 ? 6   GLU H N   1 
ATOM 42   C CA  . GLU A 1 6   ? 283.190 377.092 480.090 1.00 132.80 ? 6   GLU H CA  1 
ATOM 43   C C   . GLU A 1 6   ? 282.533 378.039 481.082 1.00 132.80 ? 6   GLU H C   1 
ATOM 44   O O   . GLU A 1 6   ? 282.810 378.001 482.283 1.00 132.80 ? 6   GLU H O   1 
ATOM 45   C CB  . GLU A 1 6   ? 282.292 375.876 479.852 1.00 132.80 ? 6   GLU H CB  1 
ATOM 46   C CG  . GLU A 1 6   ? 282.113 374.984 481.052 1.00 132.80 ? 6   GLU H CG  1 
ATOM 47   C CD  . GLU A 1 6   ? 283.062 373.812 481.028 1.00 132.80 ? 6   GLU H CD  1 
ATOM 48   O OE1 . GLU A 1 6   ? 284.026 373.842 480.241 1.00 132.80 ? 6   GLU H OE1 1 
ATOM 49   O OE2 . GLU A 1 6   ? 282.853 372.854 481.795 1.00 132.80 ? 6   GLU H OE2 1 
ATOM 50   N N   . SER A 1 7   ? 281.655 378.890 480.561 1.00 135.78 ? 7   SER H N   1 
ATOM 51   C CA  . SER A 1 7   ? 281.043 379.932 481.368 1.00 135.78 ? 7   SER H CA  1 
ATOM 52   C C   . SER A 1 7   ? 279.727 380.344 480.734 1.00 135.78 ? 7   SER H C   1 
ATOM 53   O O   . SER A 1 7   ? 279.460 380.032 479.573 1.00 135.78 ? 7   SER H O   1 
ATOM 54   C CB  . SER A 1 7   ? 281.963 381.146 481.496 1.00 135.78 ? 7   SER H CB  1 
ATOM 55   O OG  . SER A 1 7   ? 281.871 381.959 480.341 1.00 135.78 ? 7   SER H OG  1 
ATOM 56   N N   . GLY A 1 8   ? 278.917 381.054 481.510 1.00 136.60 ? 8   GLY H N   1 
ATOM 57   C CA  . GLY A 1 8   ? 277.657 381.563 481.015 1.00 136.60 ? 8   GLY H CA  1 
ATOM 58   C C   . GLY A 1 8   ? 276.478 381.111 481.847 1.00 136.60 ? 8   GLY H C   1 
ATOM 59   O O   . GLY A 1 8   ? 275.339 381.513 481.594 1.00 136.60 ? 8   GLY H O   1 
ATOM 60   N N   . GLY A 1 9   ? 276.740 380.274 482.845 1.00 140.46 ? 9   GLY H N   1 
ATOM 61   C CA  . GLY A 1 9   ? 275.678 379.742 483.669 1.00 140.46 ? 9   GLY H CA  1 
ATOM 62   C C   . GLY A 1 9   ? 275.121 380.758 484.642 1.00 140.46 ? 9   GLY H C   1 
ATOM 63   O O   . GLY A 1 9   ? 275.684 381.827 484.865 1.00 140.46 ? 9   GLY H O   1 
ATOM 64   N N   . GLY A 1 10  ? 273.984 380.410 485.226 1.00 143.05 ? 10  GLY H N   1 
ATOM 65   C CA  . GLY A 1 10  ? 273.350 381.283 486.188 1.00 143.05 ? 10  GLY H CA  1 
ATOM 66   C C   . GLY A 1 10  ? 271.884 380.936 486.354 1.00 143.05 ? 10  GLY H C   1 
ATOM 67   O O   . GLY A 1 10  ? 271.439 379.841 486.013 1.00 143.05 ? 10  GLY H O   1 
ATOM 68   N N   . LEU A 1 11  ? 271.152 381.899 486.901 1.00 145.43 ? 11  LEU H N   1 
ATOM 69   C CA  . LEU A 1 11  ? 269.728 381.724 487.144 1.00 145.43 ? 11  LEU H CA  1 
ATOM 70   C C   . LEU A 1 11  ? 268.936 382.297 485.975 1.00 145.43 ? 11  LEU H C   1 
ATOM 71   O O   . LEU A 1 11  ? 269.321 383.309 485.384 1.00 145.43 ? 11  LEU H O   1 
ATOM 72   C CB  . LEU A 1 11  ? 269.350 382.405 488.464 1.00 145.43 ? 11  LEU H CB  1 
ATOM 73   C CG  . LEU A 1 11  ? 268.074 382.131 489.269 1.00 145.43 ? 11  LEU H CG  1 
ATOM 74   C CD1 . LEU A 1 11  ? 268.279 382.679 490.665 1.00 145.43 ? 11  LEU H CD1 1 
ATOM 75   C CD2 . LEU A 1 11  ? 266.816 382.751 488.678 1.00 145.43 ? 11  LEU H CD2 1 
ATOM 76   N N   . VAL A 1 12  ? 267.822 381.642 485.644 1.00 146.70 ? 12  VAL H N   1 
ATOM 77   C CA  . VAL A 1 12  ? 266.972 382.057 484.535 1.00 146.70 ? 12  VAL H CA  1 
ATOM 78   C C   . VAL A 1 12  ? 265.568 381.513 484.776 1.00 146.70 ? 12  VAL H C   1 
ATOM 79   O O   . VAL A 1 12  ? 265.383 380.422 485.319 1.00 146.70 ? 12  VAL H O   1 
ATOM 80   C CB  . VAL A 1 12  ? 267.575 381.587 483.183 1.00 146.70 ? 12  VAL H CB  1 
ATOM 81   C CG1 . VAL A 1 12  ? 267.795 380.084 483.171 1.00 146.70 ? 12  VAL H CG1 1 
ATOM 82   C CG2 . VAL A 1 12  ? 266.754 382.054 481.982 1.00 146.70 ? 12  VAL H CG2 1 
ATOM 83   N N   . GLN A 1 13  ? 264.561 382.310 484.406 1.00 152.62 ? 13  GLN H N   1 
ATOM 84   C CA  . GLN A 1 13  ? 263.134 382.051 484.504 1.00 152.62 ? 13  GLN H CA  1 
ATOM 85   C C   . GLN A 1 13  ? 262.733 380.900 483.590 1.00 152.62 ? 13  GLN H C   1 
ATOM 86   O O   . GLN A 1 13  ? 263.325 380.718 482.521 1.00 152.62 ? 13  GLN H O   1 
ATOM 87   C CB  . GLN A 1 13  ? 262.348 383.303 484.120 1.00 152.62 ? 13  GLN H CB  1 
ATOM 88   C CG  . GLN A 1 13  ? 260.965 383.408 484.729 1.00 152.62 ? 13  GLN H CG  1 
ATOM 89   C CD  . GLN A 1 13  ? 260.985 383.355 486.244 1.00 152.62 ? 13  GLN H CD  1 
ATOM 90   O OE1 . GLN A 1 13  ? 261.846 383.956 486.887 1.00 152.62 ? 13  GLN H OE1 1 
ATOM 91   N NE2 . GLN A 1 13  ? 260.035 382.632 486.823 1.00 152.62 ? 13  GLN H NE2 1 
ATOM 92   N N   . PRO A 1 14  ? 261.759 380.087 484.004 1.00 152.10 ? 14  PRO H N   1 
ATOM 93   C CA  . PRO A 1 14  ? 261.201 379.080 483.094 1.00 152.10 ? 14  PRO H CA  1 
ATOM 94   C C   . PRO A 1 14  ? 260.504 379.724 481.909 1.00 152.10 ? 14  PRO H C   1 
ATOM 95   O O   . PRO A 1 14  ? 259.813 380.734 482.044 1.00 152.10 ? 14  PRO H O   1 
ATOM 96   C CB  . PRO A 1 14  ? 260.207 378.319 483.974 1.00 152.10 ? 14  PRO H CB  1 
ATOM 97   C CG  . PRO A 1 14  ? 260.737 378.479 485.341 1.00 152.10 ? 14  PRO H CG  1 
ATOM 98   C CD  . PRO A 1 14  ? 261.359 379.840 485.397 1.00 152.10 ? 14  PRO H CD  1 
ATOM 99   N N   . GLY A 1 15  ? 260.699 379.127 480.739 1.00 149.36 ? 15  GLY H N   1 
ATOM 100  C CA  . GLY A 1 15  ? 260.220 379.696 479.502 1.00 149.36 ? 15  GLY H CA  1 
ATOM 101  C C   . GLY A 1 15  ? 261.172 380.669 478.846 1.00 149.36 ? 15  GLY H C   1 
ATOM 102  O O   . GLY A 1 15  ? 260.845 381.207 477.782 1.00 149.36 ? 15  GLY H O   1 
ATOM 103  N N   . GLY A 1 16  ? 262.342 380.907 479.440 1.00 148.97 ? 16  GLY H N   1 
ATOM 104  C CA  . GLY A 1 16  ? 263.299 381.850 478.910 1.00 148.97 ? 16  GLY H CA  1 
ATOM 105  C C   . GLY A 1 16  ? 264.395 381.178 478.096 1.00 148.97 ? 16  GLY H C   1 
ATOM 106  O O   . GLY A 1 16  ? 264.360 379.987 477.799 1.00 148.97 ? 16  GLY H O   1 
ATOM 107  N N   . SER A 1 17  ? 265.386 381.986 477.733 1.00 143.30 ? 17  SER H N   1 
ATOM 108  C CA  . SER A 1 17  ? 266.511 381.538 476.931 1.00 143.30 ? 17  SER H CA  1 
ATOM 109  C C   . SER A 1 17  ? 267.817 381.851 477.645 1.00 143.30 ? 17  SER H C   1 
ATOM 110  O O   . SER A 1 17  ? 267.887 382.745 478.490 1.00 143.30 ? 17  SER H O   1 
ATOM 111  C CB  . SER A 1 17  ? 266.503 382.199 475.550 1.00 143.30 ? 17  SER H CB  1 
ATOM 112  O OG  . SER A 1 17  ? 267.368 381.518 474.659 1.00 143.30 ? 17  SER H OG  1 
ATOM 113  N N   . LEU A 1 18  ? 268.859 381.104 477.284 1.00 139.53 ? 18  LEU H N   1 
ATOM 114  C CA  . LEU A 1 18  ? 270.174 381.263 477.886 1.00 139.53 ? 18  LEU H CA  1 
ATOM 115  C C   . LEU A 1 18  ? 271.206 380.658 476.946 1.00 139.53 ? 18  LEU H C   1 
ATOM 116  O O   . LEU A 1 18  ? 270.953 379.617 476.338 1.00 139.53 ? 18  LEU H O   1 
ATOM 117  C CB  . LEU A 1 18  ? 270.230 380.596 479.265 1.00 139.53 ? 18  LEU H CB  1 
ATOM 118  C CG  . LEU A 1 18  ? 271.566 380.553 479.997 1.00 139.53 ? 18  LEU H CG  1 
ATOM 119  C CD1 . LEU A 1 18  ? 272.060 381.960 480.238 1.00 139.53 ? 18  LEU H CD1 1 
ATOM 120  C CD2 . LEU A 1 18  ? 271.415 379.823 481.308 1.00 139.53 ? 18  LEU H CD2 1 
ATOM 121  N N   . SER A 1 19  ? 272.355 381.315 476.822 1.00 133.57 ? 19  SER H N   1 
ATOM 122  C CA  . SER A 1 19  ? 273.412 380.886 475.915 1.00 133.57 ? 19  SER H CA  1 
ATOM 123  C C   . SER A 1 19  ? 274.686 380.617 476.699 1.00 133.57 ? 19  SER H C   1 
ATOM 124  O O   . SER A 1 19  ? 275.229 381.524 477.335 1.00 133.57 ? 19  SER H O   1 
ATOM 125  C CB  . SER A 1 19  ? 273.671 381.942 474.843 1.00 133.57 ? 19  SER H CB  1 
ATOM 126  O OG  . SER A 1 19  ? 274.754 381.557 474.019 1.00 133.57 ? 19  SER H OG  1 
ATOM 127  N N   . LEU A 1 20  ? 275.163 379.380 476.646 1.00 127.19 ? 20  LEU H N   1 
ATOM 128  C CA  . LEU A 1 20  ? 276.426 379.005 477.262 1.00 127.19 ? 20  LEU H CA  1 
ATOM 129  C C   . LEU A 1 20  ? 277.561 379.197 476.270 1.00 127.19 ? 20  LEU H C   1 
ATOM 130  O O   . LEU A 1 20  ? 277.336 379.481 475.093 1.00 127.19 ? 20  LEU H O   1 
ATOM 131  C CB  . LEU A 1 20  ? 276.402 377.555 477.738 1.00 127.19 ? 20  LEU H CB  1 
ATOM 132  C CG  . LEU A 1 20  ? 275.383 377.200 478.815 1.00 127.19 ? 20  LEU H CG  1 
ATOM 133  C CD1 . LEU A 1 20  ? 275.652 375.812 479.340 1.00 127.19 ? 20  LEU H CD1 1 
ATOM 134  C CD2 . LEU A 1 20  ? 275.428 378.202 479.940 1.00 127.19 ? 20  LEU H CD2 1 
ATOM 135  N N   . SER A 1 21  ? 278.787 379.058 476.761 1.00 130.86 ? 21  SER H N   1 
ATOM 136  C CA  . SER A 1 21  ? 279.972 379.153 475.926 1.00 130.86 ? 21  SER H CA  1 
ATOM 137  C C   . SER A 1 21  ? 281.098 378.352 476.552 1.00 130.86 ? 21  SER H C   1 
ATOM 138  O O   . SER A 1 21  ? 281.384 378.502 477.741 1.00 130.86 ? 21  SER H O   1 
ATOM 139  C CB  . SER A 1 21  ? 280.412 380.602 475.742 1.00 130.86 ? 21  SER H CB  1 
ATOM 140  O OG  . SER A 1 21  ? 279.515 381.294 474.896 1.00 130.86 ? 21  SER H OG  1 
ATOM 141  N N   . CYS A 1 22  ? 281.738 377.509 475.749 1.00 132.82 ? 22  CYS H N   1 
ATOM 142  C CA  . CYS A 1 22  ? 282.842 376.671 476.195 1.00 132.82 ? 22  CYS H CA  1 
ATOM 143  C C   . CYS A 1 22  ? 284.071 376.997 475.364 1.00 132.82 ? 22  CYS H C   1 
ATOM 144  O O   . CYS A 1 22  ? 284.034 376.898 474.134 1.00 132.82 ? 22  CYS H O   1 
ATOM 145  C CB  . CYS A 1 22  ? 282.486 375.187 476.071 1.00 132.82 ? 22  CYS H CB  1 
ATOM 146  S SG  . CYS A 1 22  ? 283.871 374.030 476.235 1.00 132.82 ? 22  CYS H SG  1 
ATOM 147  N N   . ALA A 1 23  ? 285.151 377.389 476.030 1.00 132.23 ? 23  ALA H N   1 
ATOM 148  C CA  . ALA A 1 23  ? 286.378 377.795 475.364 1.00 132.23 ? 23  ALA H CA  1 
ATOM 149  C C   . ALA A 1 23  ? 287.402 376.673 475.425 1.00 132.23 ? 23  ALA H C   1 
ATOM 150  O O   . ALA A 1 23  ? 287.492 375.959 476.427 1.00 132.23 ? 23  ALA H O   1 
ATOM 151  C CB  . ALA A 1 23  ? 286.958 379.059 475.997 1.00 132.23 ? 23  ALA H CB  1 
ATOM 152  N N   . ALA A 1 24  ? 288.172 376.526 474.353 1.00 134.80 ? 24  ALA H N   1 
ATOM 153  C CA  . ALA A 1 24  ? 289.166 375.471 474.230 1.00 134.80 ? 24  ALA H CA  1 
ATOM 154  C C   . ALA A 1 24  ? 290.536 376.081 474.001 1.00 134.80 ? 24  ALA H C   1 
ATOM 155  O O   . ALA A 1 24  ? 290.671 377.069 473.275 1.00 134.80 ? 24  ALA H O   1 
ATOM 156  C CB  . ALA A 1 24  ? 288.827 374.525 473.081 1.00 134.80 ? 24  ALA H CB  1 
ATOM 157  N N   . SER A 1 25  ? 291.555 375.494 474.625 1.00 135.59 ? 25  SER H N   1 
ATOM 158  C CA  . SER A 1 25  ? 292.920 375.973 474.470 1.00 135.59 ? 25  SER H CA  1 
ATOM 159  C C   . SER A 1 25  ? 293.882 374.805 474.593 1.00 135.59 ? 25  SER H C   1 
ATOM 160  O O   . SER A 1 25  ? 293.706 373.936 475.451 1.00 135.59 ? 25  SER H O   1 
ATOM 161  C CB  . SER A 1 25  ? 293.273 377.040 475.515 1.00 135.59 ? 25  SER H CB  1 
ATOM 162  O OG  . SER A 1 25  ? 292.260 378.022 475.643 1.00 135.59 ? 25  SER H OG  1 
ATOM 163  N N   . GLY A 1 26  ? 294.903 374.796 473.740 1.00 130.07 ? 26  GLY H N   1 
ATOM 164  C CA  . GLY A 1 26  ? 295.966 373.821 473.819 1.00 130.07 ? 26  GLY H CA  1 
ATOM 165  C C   . GLY A 1 26  ? 296.002 372.803 472.699 1.00 130.07 ? 26  GLY H C   1 
ATOM 166  O O   . GLY A 1 26  ? 296.861 371.915 472.727 1.00 130.07 ? 26  GLY H O   1 
ATOM 167  N N   . PHE A 1 27  ? 295.109 372.903 471.720 1.00 126.37 ? 27  PHE H N   1 
ATOM 168  C CA  . PHE A 1 27  ? 295.070 371.945 470.625 1.00 126.37 ? 27  PHE H CA  1 
ATOM 169  C C   . PHE A 1 27  ? 294.431 372.603 469.412 1.00 126.37 ? 27  PHE H C   1 
ATOM 170  O O   . PHE A 1 27  ? 293.899 373.712 469.490 1.00 126.37 ? 27  PHE H O   1 
ATOM 171  C CB  . PHE A 1 27  ? 294.321 370.664 471.022 1.00 126.37 ? 27  PHE H CB  1 
ATOM 172  C CG  . PHE A 1 27  ? 292.880 370.880 471.401 1.00 126.37 ? 27  PHE H CG  1 
ATOM 173  C CD1 . PHE A 1 27  ? 292.531 371.233 472.691 1.00 126.37 ? 27  PHE H CD1 1 
ATOM 174  C CD2 . PHE A 1 27  ? 291.871 370.696 470.473 1.00 126.37 ? 27  PHE H CD2 1 
ATOM 175  C CE1 . PHE A 1 27  ? 291.212 371.426 473.036 1.00 126.37 ? 27  PHE H CE1 1 
ATOM 176  C CE2 . PHE A 1 27  ? 290.551 370.888 470.814 1.00 126.37 ? 27  PHE H CE2 1 
ATOM 177  C CZ  . PHE A 1 27  ? 290.223 371.250 472.097 1.00 126.37 ? 27  PHE H CZ  1 
ATOM 178  N N   . THR A 1 28  ? 294.492 371.906 468.282 1.00 125.86 ? 28  THR H N   1 
ATOM 179  C CA  . THR A 1 28  ? 293.837 372.371 467.066 1.00 125.86 ? 28  THR H CA  1 
ATOM 180  C C   . THR A 1 28  ? 292.339 372.136 467.189 1.00 125.86 ? 28  THR H C   1 
ATOM 181  O O   . THR A 1 28  ? 291.893 370.991 467.295 1.00 125.86 ? 28  THR H O   1 
ATOM 182  C CB  . THR A 1 28  ? 294.389 371.649 465.843 1.00 125.86 ? 28  THR H CB  1 
ATOM 183  O OG1 . THR A 1 28  ? 294.142 370.244 465.970 1.00 125.86 ? 28  THR H OG1 1 
ATOM 184  C CG2 . THR A 1 28  ? 295.878 371.879 465.723 1.00 125.86 ? 28  THR H CG2 1 
ATOM 185  N N   . PHE A 1 29  ? 291.564 373.217 467.161 1.00 124.93 ? 29  PHE H N   1 
ATOM 186  C CA  . PHE A 1 29  ? 290.145 373.116 467.465 1.00 124.93 ? 29  PHE H CA  1 
ATOM 187  C C   . PHE A 1 29  ? 289.334 372.512 466.329 1.00 124.93 ? 29  PHE H C   1 
ATOM 188  O O   . PHE A 1 29  ? 288.255 371.970 466.578 1.00 124.93 ? 29  PHE H O   1 
ATOM 189  C CB  . PHE A 1 29  ? 289.589 374.490 467.812 1.00 124.93 ? 29  PHE H CB  1 
ATOM 190  C CG  . PHE A 1 29  ? 288.229 374.442 468.414 1.00 124.93 ? 29  PHE H CG  1 
ATOM 191  C CD1 . PHE A 1 29  ? 288.005 373.737 469.580 1.00 124.93 ? 29  PHE H CD1 1 
ATOM 192  C CD2 . PHE A 1 29  ? 287.168 375.082 467.803 1.00 124.93 ? 29  PHE H CD2 1 
ATOM 193  C CE1 . PHE A 1 29  ? 286.751 373.682 470.137 1.00 124.93 ? 29  PHE H CE1 1 
ATOM 194  C CE2 . PHE A 1 29  ? 285.909 375.032 468.355 1.00 124.93 ? 29  PHE H CE2 1 
ATOM 195  C CZ  . PHE A 1 29  ? 285.701 374.331 469.525 1.00 124.93 ? 29  PHE H CZ  1 
ATOM 196  N N   . THR A 1 30  ? 289.822 372.571 465.101 1.00 113.72 ? 30  THR H N   1 
ATOM 197  C CA  . THR A 1 30  ? 289.065 372.074 463.967 1.00 113.72 ? 30  THR H CA  1 
ATOM 198  C C   . THR A 1 30  ? 289.376 370.626 463.641 1.00 113.72 ? 30  THR H C   1 
ATOM 199  O O   . THR A 1 30  ? 289.312 370.245 462.471 1.00 113.72 ? 30  THR H O   1 
ATOM 200  C CB  . THR A 1 30  ? 289.330 372.928 462.734 1.00 113.72 ? 30  THR H CB  1 
ATOM 201  O OG1 . THR A 1 30  ? 290.596 372.564 462.175 1.00 113.72 ? 30  THR H OG1 1 
ATOM 202  C CG2 . THR A 1 30  ? 289.347 374.396 463.103 1.00 113.72 ? 30  THR H CG2 1 
ATOM 203  N N   . ASP A 1 31  ? 289.721 369.813 464.637 1.00 112.19 ? 31  ASP H N   1 
ATOM 204  C CA  . ASP A 1 31  ? 290.082 368.428 464.394 1.00 112.19 ? 31  ASP H CA  1 
ATOM 205  C C   . ASP A 1 31  ? 289.331 367.423 465.246 1.00 112.19 ? 31  ASP H C   1 
ATOM 206  O O   . ASP A 1 31  ? 289.396 366.229 464.950 1.00 112.19 ? 31  ASP H O   1 
ATOM 207  C CB  . ASP A 1 31  ? 291.582 368.217 464.621 1.00 112.19 ? 31  ASP H CB  1 
ATOM 208  C CG  . ASP A 1 31  ? 292.386 368.405 463.365 1.00 112.19 ? 31  ASP H CG  1 
ATOM 209  O OD1 . ASP A 1 31  ? 291.801 368.808 462.341 1.00 112.19 ? 31  ASP H OD1 1 
ATOM 210  O OD2 . ASP A 1 31  ? 293.604 368.137 463.395 1.00 112.19 ? 31  ASP H OD2 1 
ATOM 211  N N   . TYR A 1 32  ? 288.638 367.854 466.288 1.00 107.83 ? 32  TYR H N   1 
ATOM 212  C CA  . TYR A 1 32  ? 288.044 366.916 467.219 1.00 107.83 ? 32  TYR H CA  1 
ATOM 213  C C   . TYR A 1 32  ? 286.555 367.171 467.383 1.00 107.83 ? 32  TYR H C   1 
ATOM 214  O O   . TYR A 1 32  ? 286.092 368.312 467.342 1.00 107.83 ? 32  TYR H O   1 
ATOM 215  C CB  . TYR A 1 32  ? 288.726 366.996 468.572 1.00 107.83 ? 32  TYR H CB  1 
ATOM 216  C CG  . TYR A 1 32  ? 290.206 366.756 468.505 1.00 107.83 ? 32  TYR H CG  1 
ATOM 217  C CD1 . TYR A 1 32  ? 290.712 365.476 468.359 1.00 107.83 ? 32  TYR H CD1 1 
ATOM 218  C CD2 . TYR A 1 32  ? 291.099 367.808 468.597 1.00 107.83 ? 32  TYR H CD2 1 
ATOM 219  C CE1 . TYR A 1 32  ? 292.068 365.251 468.300 1.00 107.83 ? 32  TYR H CE1 1 
ATOM 220  C CE2 . TYR A 1 32  ? 292.454 367.595 468.541 1.00 107.83 ? 32  TYR H CE2 1 
ATOM 221  C CZ  . TYR A 1 32  ? 292.933 366.316 468.393 1.00 107.83 ? 32  TYR H CZ  1 
ATOM 222  O OH  . TYR A 1 32  ? 294.290 366.103 468.335 1.00 107.83 ? 32  TYR H OH  1 
ATOM 223  N N   . TYR A 1 33  ? 285.817 366.083 467.569 1.00 102.38 ? 33  TYR H N   1 
ATOM 224  C CA  . TYR A 1 33  ? 284.406 366.158 467.893 1.00 102.38 ? 33  TYR H CA  1 
ATOM 225  C C   . TYR A 1 33  ? 284.232 366.733 469.289 1.00 102.38 ? 33  TYR H C   1 
ATOM 226  O O   . TYR A 1 33  ? 284.936 366.355 470.225 1.00 102.38 ? 33  TYR H O   1 
ATOM 227  C CB  . TYR A 1 33  ? 283.775 364.772 467.844 1.00 102.38 ? 33  TYR H CB  1 
ATOM 228  C CG  . TYR A 1 33  ? 283.667 364.148 466.478 1.00 102.38 ? 33  TYR H CG  1 
ATOM 229  C CD1 . TYR A 1 33  ? 284.764 363.582 465.856 1.00 102.38 ? 33  TYR H CD1 1 
ATOM 230  C CD2 . TYR A 1 33  ? 282.452 364.092 465.829 1.00 102.38 ? 33  TYR H CD2 1 
ATOM 231  C CE1 . TYR A 1 33  ? 284.654 363.004 464.615 1.00 102.38 ? 33  TYR H CE1 1 
ATOM 232  C CE2 . TYR A 1 33  ? 282.330 363.511 464.594 1.00 102.38 ? 33  TYR H CE2 1 
ATOM 233  C CZ  . TYR A 1 33  ? 283.432 362.974 463.990 1.00 102.38 ? 33  TYR H CZ  1 
ATOM 234  O OH  . TYR A 1 33  ? 283.303 362.400 462.751 1.00 102.38 ? 33  TYR H OH  1 
ATOM 235  N N   . MET A 1 34  ? 283.277 367.642 469.436 1.00 108.44 ? 34  MET H N   1 
ATOM 236  C CA  . MET A 1 34  ? 283.055 368.317 470.708 1.00 108.44 ? 34  MET H CA  1 
ATOM 237  C C   . MET A 1 34  ? 281.656 367.995 471.196 1.00 108.44 ? 34  MET H C   1 
ATOM 238  O O   . MET A 1 34  ? 280.677 368.312 470.519 1.00 108.44 ? 34  MET H O   1 
ATOM 239  C CB  . MET A 1 34  ? 283.241 369.824 470.563 1.00 108.44 ? 34  MET H CB  1 
ATOM 240  C CG  . MET A 1 34  ? 284.624 370.225 470.107 1.00 108.44 ? 34  MET H CG  1 
ATOM 241  S SD  . MET A 1 34  ? 285.870 369.932 471.365 1.00 108.44 ? 34  MET H SD  1 
ATOM 242  C CE  . MET A 1 34  ? 285.168 370.850 472.722 1.00 108.44 ? 34  MET H CE  1 
ATOM 243  N N   . ASN A 1 35  ? 281.561 367.386 472.369 1.00 108.57 ? 35  ASN H N   1 
ATOM 244  C CA  . ASN A 1 35  ? 280.292 366.925 472.906 1.00 108.57 ? 35  ASN H CA  1 
ATOM 245  C C   . ASN A 1 35  ? 279.729 367.920 473.913 1.00 108.57 ? 35  ASN H C   1 
ATOM 246  O O   . ASN A 1 35  ? 280.303 368.974 474.177 1.00 108.57 ? 35  ASN H O   1 
ATOM 247  C CB  . ASN A 1 35  ? 280.462 365.558 473.559 1.00 108.57 ? 35  ASN H CB  1 
ATOM 248  C CG  . ASN A 1 35  ? 280.537 364.446 472.551 1.00 108.57 ? 35  ASN H CG  1 
ATOM 249  O OD1 . ASN A 1 35  ? 279.594 363.678 472.387 1.00 108.57 ? 35  ASN H OD1 1 
ATOM 250  N ND2 . ASN A 1 35  ? 281.662 364.345 471.871 1.00 108.57 ? 35  ASN H ND2 1 
ATOM 251  N N   . TRP A 1 36  ? 278.579 367.563 474.476 1.00 113.21 ? 36  TRP H N   1 
ATOM 252  C CA  . TRP A 1 36  ? 277.934 368.340 475.528 1.00 113.21 ? 36  TRP H CA  1 
ATOM 253  C C   . TRP A 1 36  ? 277.182 367.374 476.422 1.00 113.21 ? 36  TRP H C   1 
ATOM 254  O O   . TRP A 1 36  ? 276.230 366.736 475.975 1.00 113.21 ? 36  TRP H O   1 
ATOM 255  C CB  . TRP A 1 36  ? 276.969 369.375 474.955 1.00 113.21 ? 36  TRP H CB  1 
ATOM 256  C CG  . TRP A 1 36  ? 277.609 370.628 474.514 1.00 113.21 ? 36  TRP H CG  1 
ATOM 257  C CD1 . TRP A 1 36  ? 278.009 370.938 473.258 1.00 113.21 ? 36  TRP H CD1 1 
ATOM 258  C CD2 . TRP A 1 36  ? 277.912 371.761 475.323 1.00 113.21 ? 36  TRP H CD2 1 
ATOM 259  N NE1 . TRP A 1 36  ? 278.552 372.194 473.230 1.00 113.21 ? 36  TRP H NE1 1 
ATOM 260  C CE2 . TRP A 1 36  ? 278.504 372.720 474.491 1.00 113.21 ? 36  TRP H CE2 1 
ATOM 261  C CE3 . TRP A 1 36  ? 277.739 372.057 476.670 1.00 113.21 ? 36  TRP H CE3 1 
ATOM 262  C CZ2 . TRP A 1 36  ? 278.928 373.950 474.962 1.00 113.21 ? 36  TRP H CZ2 1 
ATOM 263  C CZ3 . TRP A 1 36  ? 278.166 373.273 477.139 1.00 113.21 ? 36  TRP H CZ3 1 
ATOM 264  C CH2 . TRP A 1 36  ? 278.751 374.207 476.289 1.00 113.21 ? 36  TRP H CH2 1 
ATOM 265  N N   . VAL A 1 37  ? 277.596 367.266 477.676 1.00 113.30 ? 37  VAL H N   1 
ATOM 266  C CA  . VAL A 1 37  ? 277.004 366.329 478.618 1.00 113.30 ? 37  VAL H CA  1 
ATOM 267  C C   . VAL A 1 37  ? 276.552 367.102 479.843 1.00 113.30 ? 37  VAL H C   1 
ATOM 268  O O   . VAL A 1 37  ? 277.357 367.796 480.472 1.00 113.30 ? 37  VAL H O   1 
ATOM 269  C CB  . VAL A 1 37  ? 277.997 365.223 479.005 1.00 113.30 ? 37  VAL H CB  1 
ATOM 270  C CG1 . VAL A 1 37  ? 277.501 364.458 480.209 1.00 113.30 ? 37  VAL H CG1 1 
ATOM 271  C CG2 . VAL A 1 37  ? 278.213 364.291 477.839 1.00 113.30 ? 37  VAL H CG2 1 
ATOM 272  N N   . ARG A 1 38  ? 275.274 366.990 480.176 1.00 118.61 ? 38  ARG H N   1 
ATOM 273  C CA  . ARG A 1 38  ? 274.737 367.599 481.381 1.00 118.61 ? 38  ARG H CA  1 
ATOM 274  C C   . ARG A 1 38  ? 274.545 366.538 482.452 1.00 118.61 ? 38  ARG H C   1 
ATOM 275  O O   . ARG A 1 38  ? 274.520 365.338 482.172 1.00 118.61 ? 38  ARG H O   1 
ATOM 276  C CB  . ARG A 1 38  ? 273.411 368.309 481.101 1.00 118.61 ? 38  ARG H CB  1 
ATOM 277  C CG  . ARG A 1 38  ? 272.198 367.416 481.168 1.00 118.61 ? 38  ARG H CG  1 
ATOM 278  C CD  . ARG A 1 38  ? 270.928 368.209 480.999 1.00 118.61 ? 38  ARG H CD  1 
ATOM 279  N NE  . ARG A 1 38  ? 269.763 367.336 480.980 1.00 118.61 ? 38  ARG H NE  1 
ATOM 280  C CZ  . ARG A 1 38  ? 268.539 367.738 480.667 1.00 118.61 ? 38  ARG H CZ  1 
ATOM 281  N NH1 . ARG A 1 38  ? 268.323 369.002 480.344 1.00 118.61 ? 38  ARG H NH1 1 
ATOM 282  N NH2 . ARG A 1 38  ? 267.535 366.874 480.674 1.00 118.61 ? 38  ARG H NH2 1 
ATOM 283  N N   . GLN A 1 39  ? 274.421 366.993 483.689 1.00 123.49 ? 39  GLN H N   1 
ATOM 284  C CA  . GLN A 1 39  ? 274.217 366.074 484.797 1.00 123.49 ? 39  GLN H CA  1 
ATOM 285  C C   . GLN A 1 39  ? 273.391 366.724 485.893 1.00 123.49 ? 39  GLN H C   1 
ATOM 286  O O   . GLN A 1 39  ? 273.747 367.803 486.377 1.00 123.49 ? 39  GLN H O   1 
ATOM 287  C CB  . GLN A 1 39  ? 275.548 365.613 485.379 1.00 123.49 ? 39  GLN H CB  1 
ATOM 288  C CG  . GLN A 1 39  ? 275.385 364.638 486.522 1.00 123.49 ? 39  GLN H CG  1 
ATOM 289  C CD  . GLN A 1 39  ? 276.652 364.456 487.317 1.00 123.49 ? 39  GLN H CD  1 
ATOM 290  O OE1 . GLN A 1 39  ? 277.554 365.286 487.265 1.00 123.49 ? 39  GLN H OE1 1 
ATOM 291  N NE2 . GLN A 1 39  ? 276.731 363.359 488.058 1.00 123.49 ? 39  GLN H NE2 1 
ATOM 292  N N   . PRO A 1 40  ? 272.307 366.091 486.331 1.00 128.95 ? 40  PRO H N   1 
ATOM 293  C CA  . PRO A 1 40  ? 271.528 366.635 487.446 1.00 128.95 ? 40  PRO H CA  1 
ATOM 294  C C   . PRO A 1 40  ? 272.260 366.468 488.769 1.00 128.95 ? 40  PRO H C   1 
ATOM 295  O O   . PRO A 1 40  ? 273.395 365.996 488.843 1.00 128.95 ? 40  PRO H O   1 
ATOM 296  C CB  . PRO A 1 40  ? 270.237 365.814 487.418 1.00 128.95 ? 40  PRO H CB  1 
ATOM 297  C CG  . PRO A 1 40  ? 270.234 365.119 486.097 1.00 128.95 ? 40  PRO H CG  1 
ATOM 298  C CD  . PRO A 1 40  ? 271.664 364.907 485.751 1.00 128.95 ? 40  PRO H CD  1 
ATOM 299  N N   . SER A 1 41  ? 271.573 366.859 489.836 1.00 133.59 ? 41  SER H N   1 
ATOM 300  C CA  . SER A 1 41  ? 272.179 366.937 491.162 1.00 133.59 ? 41  SER H CA  1 
ATOM 301  C C   . SER A 1 41  ? 272.395 365.534 491.712 1.00 133.59 ? 41  SER H C   1 
ATOM 302  O O   . SER A 1 41  ? 271.503 364.952 492.330 1.00 133.59 ? 41  SER H O   1 
ATOM 303  C CB  . SER A 1 41  ? 271.291 367.755 492.089 1.00 133.59 ? 41  SER H CB  1 
ATOM 304  O OG  . SER A 1 41  ? 269.956 367.284 492.039 1.00 133.59 ? 41  SER H OG  1 
ATOM 305  N N   . GLY A 1 42  ? 273.592 364.994 491.496 1.00 132.96 ? 42  GLY H N   1 
ATOM 306  C CA  . GLY A 1 42  ? 273.947 363.691 492.028 1.00 132.96 ? 42  GLY H CA  1 
ATOM 307  C C   . GLY A 1 42  ? 273.243 362.514 491.391 1.00 132.96 ? 42  GLY H C   1 
ATOM 308  O O   . GLY A 1 42  ? 273.046 361.492 492.052 1.00 132.96 ? 42  GLY H O   1 
ATOM 309  N N   . LYS A 1 43  ? 272.850 362.628 490.129 1.00 130.72 ? 43  LYS H N   1 
ATOM 310  C CA  . LYS A 1 43  ? 272.160 361.559 489.420 1.00 130.72 ? 43  LYS H CA  1 
ATOM 311  C C   . LYS A 1 43  ? 273.025 361.101 488.250 1.00 130.72 ? 43  LYS H C   1 
ATOM 312  O O   . LYS A 1 43  ? 274.183 361.497 488.114 1.00 130.72 ? 43  LYS H O   1 
ATOM 313  C CB  . LYS A 1 43  ? 270.771 362.002 488.940 1.00 130.72 ? 43  LYS H CB  1 
ATOM 314  C CG  . LYS A 1 43  ? 269.933 362.881 489.886 1.00 130.72 ? 43  LYS H CG  1 
ATOM 315  C CD  . LYS A 1 43  ? 269.768 362.351 491.315 1.00 130.72 ? 43  LYS H CD  1 
ATOM 316  C CE  . LYS A 1 43  ? 269.154 360.966 491.383 1.00 130.72 ? 43  LYS H CE  1 
ATOM 317  N NZ  . LYS A 1 43  ? 268.997 360.532 492.799 1.00 130.72 ? 43  LYS H NZ  1 
ATOM 318  N N   . ALA A 1 44  ? 272.449 360.249 487.407 1.00 126.90 ? 44  ALA H N   1 
ATOM 319  C CA  . ALA A 1 44  ? 273.164 359.721 486.260 1.00 126.90 ? 44  ALA H CA  1 
ATOM 320  C C   . ALA A 1 44  ? 273.339 360.796 485.192 1.00 126.90 ? 44  ALA H C   1 
ATOM 321  O O   . ALA A 1 44  ? 272.579 361.762 485.114 1.00 126.90 ? 44  ALA H O   1 
ATOM 322  C CB  . ALA A 1 44  ? 272.427 358.519 485.674 1.00 126.90 ? 44  ALA H CB  1 
ATOM 323  N N   . LEU A 1 45  ? 274.361 360.614 484.364 1.00 118.01 ? 45  LEU H N   1 
ATOM 324  C CA  . LEU A 1 45  ? 274.665 361.581 483.322 1.00 118.01 ? 45  LEU H CA  1 
ATOM 325  C C   . LEU A 1 45  ? 273.671 361.467 482.174 1.00 118.01 ? 45  LEU H C   1 
ATOM 326  O O   . LEU A 1 45  ? 272.938 360.485 482.049 1.00 118.01 ? 45  LEU H O   1 
ATOM 327  C CB  . LEU A 1 45  ? 276.083 361.373 482.805 1.00 118.01 ? 45  LEU H CB  1 
ATOM 328  C CG  . LEU A 1 45  ? 277.201 361.543 483.828 1.00 118.01 ? 45  LEU H CG  1 
ATOM 329  C CD1 . LEU A 1 45  ? 278.366 360.650 483.481 1.00 118.01 ? 45  LEU H CD1 1 
ATOM 330  C CD2 . LEU A 1 45  ? 277.654 362.973 483.854 1.00 118.01 ? 45  LEU H CD2 1 
ATOM 331  N N   . GLU A 1 46  ? 273.646 362.496 481.334 1.00 117.45 ? 46  GLU H N   1 
ATOM 332  C CA  . GLU A 1 46  ? 272.794 362.534 480.156 1.00 117.45 ? 46  GLU H CA  1 
ATOM 333  C C   . GLU A 1 46  ? 273.576 363.166 479.020 1.00 117.45 ? 46  GLU H C   1 
ATOM 334  O O   . GLU A 1 46  ? 274.320 364.125 479.239 1.00 117.45 ? 46  GLU H O   1 
ATOM 335  C CB  . GLU A 1 46  ? 271.519 363.328 480.418 1.00 117.45 ? 46  GLU H CB  1 
ATOM 336  C CG  . GLU A 1 46  ? 270.392 362.510 480.999 1.00 117.45 ? 46  GLU H CG  1 
ATOM 337  C CD  . GLU A 1 46  ? 269.399 363.357 481.769 1.00 117.45 ? 46  GLU H CD  1 
ATOM 338  O OE1 . GLU A 1 46  ? 269.084 364.474 481.305 1.00 117.45 ? 46  GLU H OE1 1 
ATOM 339  O OE2 . GLU A 1 46  ? 268.938 362.911 482.841 1.00 117.45 ? 46  GLU H OE2 1 
ATOM 340  N N   . TRP A 1 47  ? 273.412 362.634 477.818 1.00 108.28 ? 47  TRP H N   1 
ATOM 341  C CA  . TRP A 1 47  ? 274.132 363.130 476.658 1.00 108.28 ? 47  TRP H CA  1 
ATOM 342  C C   . TRP A 1 47  ? 273.205 363.986 475.809 1.00 108.28 ? 47  TRP H C   1 
ATOM 343  O O   . TRP A 1 47  ? 272.034 363.645 475.627 1.00 108.28 ? 47  TRP H O   1 
ATOM 344  C CB  . TRP A 1 47  ? 274.687 361.961 475.851 1.00 108.28 ? 47  TRP H CB  1 
ATOM 345  C CG  . TRP A 1 47  ? 275.292 362.342 474.558 1.00 108.28 ? 47  TRP H CG  1 
ATOM 346  C CD1 . TRP A 1 47  ? 276.526 362.862 474.356 1.00 108.28 ? 47  TRP H CD1 1 
ATOM 347  C CD2 . TRP A 1 47  ? 274.697 362.205 473.272 1.00 108.28 ? 47  TRP H CD2 1 
ATOM 348  N NE1 . TRP A 1 47  ? 276.737 363.070 473.019 1.00 108.28 ? 47  TRP H NE1 1 
ATOM 349  C CE2 . TRP A 1 47  ? 275.622 362.673 472.333 1.00 108.28 ? 47  TRP H CE2 1 
ATOM 350  C CE3 . TRP A 1 47  ? 273.467 361.736 472.823 1.00 108.28 ? 47  TRP H CE3 1 
ATOM 351  C CZ2 . TRP A 1 47  ? 275.357 362.682 470.979 1.00 108.28 ? 47  TRP H CZ2 1 
ATOM 352  C CZ3 . TRP A 1 47  ? 273.206 361.749 471.475 1.00 108.28 ? 47  TRP H CZ3 1 
ATOM 353  C CH2 . TRP A 1 47  ? 274.144 362.220 470.569 1.00 108.28 ? 47  TRP H CH2 1 
ATOM 354  N N   . LEU A 1 48  ? 273.727 365.096 475.294 1.00 112.62 ? 48  LEU H N   1 
ATOM 355  C CA  . LEU A 1 48  ? 272.916 366.054 474.555 1.00 112.62 ? 48  LEU H CA  1 
ATOM 356  C C   . LEU A 1 48  ? 273.185 366.053 473.061 1.00 112.62 ? 48  LEU H C   1 
ATOM 357  O O   . LEU A 1 48  ? 272.244 365.936 472.273 1.00 112.62 ? 48  LEU H O   1 
ATOM 358  C CB  . LEU A 1 48  ? 273.135 367.464 475.097 1.00 112.62 ? 48  LEU H CB  1 
ATOM 359  C CG  . LEU A 1 48  ? 272.755 367.655 476.559 1.00 112.62 ? 48  LEU H CG  1 
ATOM 360  C CD1 . LEU A 1 48  ? 272.908 369.105 476.942 1.00 112.62 ? 48  LEU H CD1 1 
ATOM 361  C CD2 . LEU A 1 48  ? 271.339 367.183 476.806 1.00 112.62 ? 48  LEU H CD2 1 
ATOM 362  N N   . GLY A 1 49  ? 274.432 366.190 472.645 1.00 108.41 ? 49  GLY H N   1 
ATOM 363  C CA  . GLY A 1 49  ? 274.739 366.192 471.231 1.00 108.41 ? 49  GLY H CA  1 
ATOM 364  C C   . GLY A 1 49  ? 276.143 366.666 470.974 1.00 108.41 ? 49  GLY H C   1 
ATOM 365  O O   . GLY A 1 49  ? 276.765 367.333 471.795 1.00 108.41 ? 49  GLY H O   1 
ATOM 366  N N   . PHE A 1 50  ? 276.657 366.313 469.804 1.00 102.11 ? 50  PHE H N   1 
ATOM 367  C CA  . PHE A 1 50  ? 277.999 366.731 469.441 1.00 102.11 ? 50  PHE H CA  1 
ATOM 368  C C   . PHE A 1 50  ? 278.000 367.427 468.088 1.00 102.11 ? 50  PHE H C   1 
ATOM 369  O O   . PHE A 1 50  ? 276.997 367.473 467.379 1.00 102.11 ? 50  PHE H O   1 
ATOM 370  C CB  . PHE A 1 50  ? 278.981 365.551 469.462 1.00 102.11 ? 50  PHE H CB  1 
ATOM 371  C CG  . PHE A 1 50  ? 278.690 364.463 468.467 1.00 102.11 ? 50  PHE H CG  1 
ATOM 372  C CD1 . PHE A 1 50  ? 279.266 364.468 467.215 1.00 102.11 ? 50  PHE H CD1 1 
ATOM 373  C CD2 . PHE A 1 50  ? 277.907 363.394 468.816 1.00 102.11 ? 50  PHE H CD2 1 
ATOM 374  C CE1 . PHE A 1 50  ? 279.017 363.454 466.321 1.00 102.11 ? 50  PHE H CE1 1 
ATOM 375  C CE2 . PHE A 1 50  ? 277.656 362.379 467.924 1.00 102.11 ? 50  PHE H CE2 1 
ATOM 376  C CZ  . PHE A 1 50  ? 278.214 362.411 466.679 1.00 102.11 ? 50  PHE H CZ  1 
ATOM 377  N N   . LEU A 1 51  ? 279.164 367.967 467.745 1.00 103.45 ? 51  LEU H N   1 
ATOM 378  C CA  . LEU A 1 51  ? 279.374 368.709 466.511 1.00 103.45 ? 51  LEU H CA  1 
ATOM 379  C C   . LEU A 1 51  ? 280.661 368.210 465.879 1.00 103.45 ? 51  LEU H C   1 
ATOM 380  O O   . LEU A 1 51  ? 281.708 368.219 466.528 1.00 103.45 ? 51  LEU H O   1 
ATOM 381  C CB  . LEU A 1 51  ? 279.448 370.209 466.785 1.00 103.45 ? 51  LEU H CB  1 
ATOM 382  C CG  . LEU A 1 51  ? 279.800 371.122 465.617 1.00 103.45 ? 51  LEU H CG  1 
ATOM 383  C CD1 . LEU A 1 51  ? 278.823 372.263 465.548 1.00 103.45 ? 51  LEU H CD1 1 
ATOM 384  C CD2 . LEU A 1 51  ? 281.201 371.670 465.792 1.00 103.45 ? 51  LEU H CD2 1 
ATOM 385  N N   . ARG A 1 52  ? 280.588 367.796 464.620 1.00 99.70  ? 52  ARG H N   1 
ATOM 386  C CA  . ARG A 1 52  ? 281.710 367.134 463.977 1.00 99.70  ? 52  ARG H CA  1 
ATOM 387  C C   . ARG A 1 52  ? 282.785 368.136 463.569 1.00 99.70  ? 52  ARG H C   1 
ATOM 388  O O   . ARG A 1 52  ? 282.578 369.349 463.561 1.00 99.70  ? 52  ARG H O   1 
ATOM 389  C CB  . ARG A 1 52  ? 281.223 366.353 462.769 1.00 99.70  ? 52  ARG H CB  1 
ATOM 390  C CG  . ARG A 1 52  ? 279.875 365.751 463.002 1.00 99.70  ? 52  ARG H CG  1 
ATOM 391  C CD  . ARG A 1 52  ? 279.687 364.503 462.209 1.00 99.70  ? 52  ARG H CD  1 
ATOM 392  N NE  . ARG A 1 52  ? 278.282 364.142 462.154 1.00 99.70  ? 52  ARG H NE  1 
ATOM 393  C CZ  . ARG A 1 52  ? 277.840 362.971 461.732 1.00 99.70  ? 52  ARG H CZ  1 
ATOM 394  N NH1 . ARG A 1 52  ? 278.699 362.056 461.324 1.00 99.70  ? 52  ARG H NH1 1 
ATOM 395  N NH2 . ARG A 1 52  ? 276.548 362.715 461.710 1.00 99.70  ? 52  ARG H NH2 1 
ATOM 396  N N   . ASN A 1 53  ? 283.950 367.606 463.209 1.00 99.84  ? 53  ASN H N   1 
ATOM 397  C CA  . ASN A 1 53  ? 285.105 368.434 462.895 1.00 99.84  ? 53  ASN H CA  1 
ATOM 398  C C   . ASN A 1 53  ? 284.976 368.985 461.480 1.00 99.84  ? 53  ASN H C   1 
ATOM 399  O O   . ASN A 1 53  ? 283.962 368.798 460.806 1.00 99.84  ? 53  ASN H O   1 
ATOM 400  C CB  . ASN A 1 53  ? 286.390 367.639 463.087 1.00 99.84  ? 53  ASN H CB  1 
ATOM 401  C CG  . ASN A 1 53  ? 286.313 366.267 462.486 1.00 99.84  ? 53  ASN H CG  1 
ATOM 402  O OD1 . ASN A 1 53  ? 285.320 365.907 461.868 1.00 99.84  ? 53  ASN H OD1 1 
ATOM 403  N ND2 . ASN A 1 53  ? 287.365 365.486 462.664 1.00 99.84  ? 53  ASN H ND2 1 
ATOM 404  N N   . LYS A 1 54  ? 286.019 369.672 461.009 1.00 100.20 ? 54  LYS H N   1 
ATOM 405  C CA  . LYS A 1 54  ? 285.932 370.349 459.720 1.00 100.20 ? 54  LYS H CA  1 
ATOM 406  C C   . LYS A 1 54  ? 285.979 369.368 458.563 1.00 100.20 ? 54  LYS H C   1 
ATOM 407  O O   . LYS A 1 54  ? 285.438 369.651 457.491 1.00 100.20 ? 54  LYS H O   1 
ATOM 408  C CB  . LYS A 1 54  ? 287.051 371.372 459.576 1.00 100.20 ? 54  LYS H CB  1 
ATOM 409  C CG  . LYS A 1 54  ? 286.736 372.455 458.562 1.00 100.20 ? 54  LYS H CG  1 
ATOM 410  C CD  . LYS A 1 54  ? 287.862 373.451 458.424 1.00 100.20 ? 54  LYS H CD  1 
ATOM 411  C CE  . LYS A 1 54  ? 289.114 372.785 457.914 1.00 100.20 ? 54  LYS H CE  1 
ATOM 412  N NZ  . LYS A 1 54  ? 290.151 373.788 457.581 1.00 100.20 ? 54  LYS H NZ  1 
ATOM 413  N N   . ALA A 1 55  ? 286.590 368.210 458.761 1.00 95.53  ? 55  ALA H N   1 
ATOM 414  C CA  . ALA A 1 55  ? 286.689 367.236 457.689 1.00 95.53  ? 55  ALA H CA  1 
ATOM 415  C C   . ALA A 1 55  ? 285.382 366.506 457.415 1.00 95.53  ? 55  ALA H C   1 
ATOM 416  O O   . ALA A 1 55  ? 285.302 365.772 456.429 1.00 95.53  ? 55  ALA H O   1 
ATOM 417  C CB  . ALA A 1 55  ? 287.784 366.225 458.011 1.00 95.53  ? 55  ALA H CB  1 
ATOM 418  N N   . ASN A 1 56  ? 284.365 366.680 458.252 1.00 94.55  ? 56  ASN H N   1 
ATOM 419  C CA  . ASN A 1 56  ? 283.081 366.030 458.051 1.00 94.55  ? 56  ASN H CA  1 
ATOM 420  C C   . ASN A 1 56  ? 281.931 367.011 457.907 1.00 94.55  ? 56  ASN H C   1 
ATOM 421  O O   . ASN A 1 56  ? 280.773 366.588 457.908 1.00 94.55  ? 56  ASN H O   1 
ATOM 422  C CB  . ASN A 1 56  ? 282.801 365.058 459.193 1.00 94.55  ? 56  ASN H CB  1 
ATOM 423  C CG  . ASN A 1 56  ? 283.789 363.925 459.228 1.00 94.55  ? 56  ASN H CG  1 
ATOM 424  O OD1 . ASN A 1 56  ? 284.134 363.411 460.289 1.00 94.55  ? 56  ASN H OD1 1 
ATOM 425  N ND2 . ASN A 1 56  ? 284.264 363.535 458.061 1.00 94.55  ? 56  ASN H ND2 1 
ATOM 426  N N   . GLY A 1 57  ? 282.209 368.304 457.804 1.00 99.92  ? 57  GLY H N   1 
ATOM 427  C CA  . GLY A 1 57  ? 281.213 369.267 457.394 1.00 99.92  ? 57  GLY H CA  1 
ATOM 428  C C   . GLY A 1 57  ? 280.483 370.006 458.491 1.00 99.92  ? 57  GLY H C   1 
ATOM 429  O O   . GLY A 1 57  ? 279.459 370.632 458.198 1.00 99.92  ? 57  GLY H O   1 
ATOM 430  N N   . TYR A 1 58  ? 280.962 369.931 459.738 1.00 102.61 ? 58  TYR H N   1 
ATOM 431  C CA  . TYR A 1 58  ? 280.453 370.701 460.880 1.00 102.61 ? 58  TYR H CA  1 
ATOM 432  C C   . TYR A 1 58  ? 278.984 370.415 461.186 1.00 102.61 ? 58  TYR H C   1 
ATOM 433  O O   . TYR A 1 58  ? 278.253 371.300 461.628 1.00 102.61 ? 58  TYR H O   1 
ATOM 434  C CB  . TYR A 1 58  ? 280.658 372.204 460.679 1.00 102.61 ? 58  TYR H CB  1 
ATOM 435  C CG  . TYR A 1 58  ? 282.069 372.677 460.874 1.00 102.61 ? 58  TYR H CG  1 
ATOM 436  C CD1 . TYR A 1 58  ? 282.859 372.166 461.887 1.00 102.61 ? 58  TYR H CD1 1 
ATOM 437  C CD2 . TYR A 1 58  ? 282.611 373.648 460.047 1.00 102.61 ? 58  TYR H CD2 1 
ATOM 438  C CE1 . TYR A 1 58  ? 284.149 372.605 462.069 1.00 102.61 ? 58  TYR H CE1 1 
ATOM 439  C CE2 . TYR A 1 58  ? 283.898 374.092 460.221 1.00 102.61 ? 58  TYR H CE2 1 
ATOM 440  C CZ  . TYR A 1 58  ? 284.660 373.568 461.233 1.00 102.61 ? 58  TYR H CZ  1 
ATOM 441  O OH  . TYR A 1 58  ? 285.945 374.009 461.410 1.00 102.61 ? 58  TYR H OH  1 
ATOM 442  N N   . THR A 1 59  ? 278.532 369.188 460.961 1.00 101.53 ? 59  THR H N   1 
ATOM 443  C CA  . THR A 1 59  ? 277.145 368.855 461.241 1.00 101.53 ? 59  THR H CA  1 
ATOM 444  C C   . THR A 1 59  ? 276.951 368.549 462.722 1.00 101.53 ? 59  THR H C   1 
ATOM 445  O O   . THR A 1 59  ? 277.906 368.350 463.471 1.00 101.53 ? 59  THR H O   1 
ATOM 446  C CB  . THR A 1 59  ? 276.706 367.660 460.410 1.00 101.53 ? 59  THR H CB  1 
ATOM 447  O OG1 . THR A 1 59  ? 277.255 366.468 460.978 1.00 101.53 ? 59  THR H OG1 1 
ATOM 448  C CG2 . THR A 1 59  ? 277.200 367.802 458.991 1.00 101.53 ? 59  THR H CG2 1 
ATOM 449  N N   . THR A 1 60  ? 275.689 368.525 463.143 1.00 104.47 ? 60  THR H N   1 
ATOM 450  C CA  . THR A 1 60  ? 275.318 368.268 464.526 1.00 104.47 ? 60  THR H CA  1 
ATOM 451  C C   . THR A 1 60  ? 274.408 367.053 464.619 1.00 104.47 ? 60  THR H C   1 
ATOM 452  O O   . THR A 1 60  ? 273.665 366.737 463.690 1.00 104.47 ? 60  THR H O   1 
ATOM 453  C CB  . THR A 1 60  ? 274.597 369.470 465.134 1.00 104.47 ? 60  THR H CB  1 
ATOM 454  O OG1 . THR A 1 60  ? 273.375 369.692 464.424 1.00 104.47 ? 60  THR H OG1 1 
ATOM 455  C CG2 . THR A 1 60  ? 275.446 370.711 465.043 1.00 104.47 ? 60  THR H CG2 1 
ATOM 456  N N   . GLU A 1 61  ? 274.472 366.364 465.764 1.00 107.61 ? 61  GLU H N   1 
ATOM 457  C CA  . GLU A 1 61  ? 273.578 365.236 466.038 1.00 107.61 ? 61  GLU H CA  1 
ATOM 458  C C   . GLU A 1 61  ? 273.060 365.387 467.463 1.00 107.61 ? 61  GLU H C   1 
ATOM 459  O O   . GLU A 1 61  ? 273.715 364.936 468.402 1.00 107.61 ? 61  GLU H O   1 
ATOM 460  C CB  . GLU A 1 61  ? 274.273 363.893 465.875 1.00 107.61 ? 61  GLU H CB  1 
ATOM 461  C CG  . GLU A 1 61  ? 274.997 363.679 464.583 1.00 107.61 ? 61  GLU H CG  1 
ATOM 462  C CD  . GLU A 1 61  ? 274.044 363.528 463.432 1.00 107.61 ? 61  GLU H CD  1 
ATOM 463  O OE1 . GLU A 1 61  ? 274.356 364.044 462.340 1.00 107.61 ? 61  GLU H OE1 1 
ATOM 464  O OE2 . GLU A 1 61  ? 272.984 362.898 463.618 1.00 107.61 ? 61  GLU H OE2 1 
ATOM 465  N N   . TYR A 1 62  ? 271.879 365.974 467.615 1.00 112.42 ? 62  TYR H N   1 
ATOM 466  C CA  . TYR A 1 62  ? 271.307 366.159 468.938 1.00 112.42 ? 62  TYR H CA  1 
ATOM 467  C C   . TYR A 1 62  ? 270.733 364.850 469.462 1.00 112.42 ? 62  TYR H C   1 
ATOM 468  O O   . TYR A 1 62  ? 270.667 363.841 468.762 1.00 112.42 ? 62  TYR H O   1 
ATOM 469  C CB  . TYR A 1 62  ? 270.228 367.231 468.911 1.00 112.42 ? 62  TYR H CB  1 
ATOM 470  C CG  . TYR A 1 62  ? 270.673 368.489 468.243 1.00 112.42 ? 62  TYR H CG  1 
ATOM 471  C CD1 . TYR A 1 62  ? 271.589 369.322 468.851 1.00 112.42 ? 62  TYR H CD1 1 
ATOM 472  C CD2 . TYR A 1 62  ? 270.186 368.838 467.000 1.00 112.42 ? 62  TYR H CD2 1 
ATOM 473  C CE1 . TYR A 1 62  ? 272.007 370.472 468.242 1.00 112.42 ? 62  TYR H CE1 1 
ATOM 474  C CE2 . TYR A 1 62  ? 270.595 369.986 466.382 1.00 112.42 ? 62  TYR H CE2 1 
ATOM 475  C CZ  . TYR A 1 62  ? 271.507 370.799 467.006 1.00 112.42 ? 62  TYR H CZ  1 
ATOM 476  O OH  . TYR A 1 62  ? 271.921 371.953 466.386 1.00 112.42 ? 62  TYR H OH  1 
ATOM 477  N N   . SER A 1 63  ? 270.298 364.875 470.714 1.00 119.25 ? 63  SER H N   1 
ATOM 478  C CA  . SER A 1 63  ? 269.614 363.734 471.300 1.00 119.25 ? 63  SER H CA  1 
ATOM 479  C C   . SER A 1 63  ? 268.142 363.787 470.910 1.00 119.25 ? 63  SER H C   1 
ATOM 480  O O   . SER A 1 63  ? 267.716 364.614 470.101 1.00 119.25 ? 63  SER H O   1 
ATOM 481  C CB  . SER A 1 63  ? 269.798 363.720 472.810 1.00 119.25 ? 63  SER H CB  1 
ATOM 482  O OG  . SER A 1 63  ? 268.849 362.864 473.415 1.00 119.25 ? 63  SER H OG  1 
ATOM 483  N N   . ALA A 1 64  ? 267.334 362.910 471.491 1.00 125.79 ? 64  ALA H N   1 
ATOM 484  C CA  . ALA A 1 64  ? 265.926 362.866 471.128 1.00 125.79 ? 64  ALA H CA  1 
ATOM 485  C C   . ALA A 1 64  ? 265.084 363.859 471.909 1.00 125.79 ? 64  ALA H C   1 
ATOM 486  O O   . ALA A 1 64  ? 264.155 364.446 471.348 1.00 125.79 ? 64  ALA H O   1 
ATOM 487  C CB  . ALA A 1 64  ? 265.373 361.455 471.335 1.00 125.79 ? 64  ALA H CB  1 
ATOM 488  N N   . SER A 1 65  ? 265.395 364.075 473.184 1.00 128.09 ? 65  SER H N   1 
ATOM 489  C CA  . SER A 1 65  ? 264.552 364.906 474.032 1.00 128.09 ? 65  SER H CA  1 
ATOM 490  C C   . SER A 1 65  ? 264.800 366.393 473.849 1.00 128.09 ? 65  SER H C   1 
ATOM 491  O O   . SER A 1 65  ? 263.895 367.197 474.100 1.00 128.09 ? 65  SER H O   1 
ATOM 492  C CB  . SER A 1 65  ? 264.762 364.534 475.500 1.00 128.09 ? 65  SER H CB  1 
ATOM 493  O OG  . SER A 1 65  ? 266.126 364.652 475.862 1.00 128.09 ? 65  SER H OG  1 
ATOM 494  N N   . VAL A 1 66  ? 265.994 366.785 473.416 1.00 127.97 ? 66  VAL H N   1 
ATOM 495  C CA  . VAL A 1 66  ? 266.343 368.189 473.265 1.00 127.97 ? 66  VAL H CA  1 
ATOM 496  C C   . VAL A 1 66  ? 266.358 368.614 471.805 1.00 127.97 ? 66  VAL H C   1 
ATOM 497  O O   . VAL A 1 66  ? 266.866 369.692 471.483 1.00 127.97 ? 66  VAL H O   1 
ATOM 498  C CB  . VAL A 1 66  ? 267.684 368.502 473.942 1.00 127.97 ? 66  VAL H CB  1 
ATOM 499  C CG1 . VAL A 1 66  ? 267.616 368.136 475.402 1.00 127.97 ? 66  VAL H CG1 1 
ATOM 500  C CG2 . VAL A 1 66  ? 268.795 367.736 473.273 1.00 127.97 ? 66  VAL H CG2 1 
ATOM 501  N N   . LYS A 1 67  ? 265.804 367.799 470.917 1.00 128.06 ? 67  LYS H N   1 
ATOM 502  C CA  . LYS A 1 67  ? 265.783 368.123 469.498 1.00 128.06 ? 67  LYS H CA  1 
ATOM 503  C C   . LYS A 1 67  ? 264.819 369.270 469.244 1.00 128.06 ? 67  LYS H C   1 
ATOM 504  O O   . LYS A 1 67  ? 263.633 369.179 469.570 1.00 128.06 ? 67  LYS H O   1 
ATOM 505  C CB  . LYS A 1 67  ? 265.379 366.897 468.689 1.00 128.06 ? 67  LYS H CB  1 
ATOM 506  C CG  . LYS A 1 67  ? 265.149 367.171 467.221 1.00 128.06 ? 67  LYS H CG  1 
ATOM 507  C CD  . LYS A 1 67  ? 266.457 367.430 466.511 1.00 128.06 ? 67  LYS H CD  1 
ATOM 508  C CE  . LYS A 1 67  ? 266.249 367.584 465.017 1.00 128.06 ? 67  LYS H CE  1 
ATOM 509  N NZ  . LYS A 1 67  ? 267.543 367.729 464.301 1.00 128.06 ? 67  LYS H NZ  1 
ATOM 510  N N   . GLY A 1 68  ? 265.329 370.355 468.674 1.00 131.85 ? 68  GLY H N   1 
ATOM 511  C CA  . GLY A 1 68  ? 264.537 371.523 468.385 1.00 131.85 ? 68  GLY H CA  1 
ATOM 512  C C   . GLY A 1 68  ? 264.589 372.598 469.449 1.00 131.85 ? 68  GLY H C   1 
ATOM 513  O O   . GLY A 1 68  ? 264.297 373.760 469.149 1.00 131.85 ? 68  GLY H O   1 
ATOM 514  N N   . ARG A 1 69  ? 264.954 372.247 470.678 1.00 134.50 ? 69  ARG H N   1 
ATOM 515  C CA  . ARG A 1 69  ? 265.065 373.230 471.743 1.00 134.50 ? 69  ARG H CA  1 
ATOM 516  C C   . ARG A 1 69  ? 266.476 373.759 471.920 1.00 134.50 ? 69  ARG H C   1 
ATOM 517  O O   . ARG A 1 69  ? 266.648 374.954 472.175 1.00 134.50 ? 69  ARG H O   1 
ATOM 518  C CB  . ARG A 1 69  ? 264.584 372.637 473.070 1.00 134.50 ? 69  ARG H CB  1 
ATOM 519  C CG  . ARG A 1 69  ? 263.168 372.116 473.020 1.00 134.50 ? 69  ARG H CG  1 
ATOM 520  C CD  . ARG A 1 69  ? 262.476 372.266 474.356 1.00 134.50 ? 69  ARG H CD  1 
ATOM 521  N NE  . ARG A 1 69  ? 262.812 371.195 475.284 1.00 134.50 ? 69  ARG H NE  1 
ATOM 522  C CZ  . ARG A 1 69  ? 263.667 371.323 476.291 1.00 134.50 ? 69  ARG H CZ  1 
ATOM 523  N NH1 . ARG A 1 69  ? 264.281 372.478 476.493 1.00 134.50 ? 69  ARG H NH1 1 
ATOM 524  N NH2 . ARG A 1 69  ? 263.910 370.297 477.093 1.00 134.50 ? 69  ARG H NH2 1 
ATOM 525  N N   . PHE A 1 70  ? 267.484 372.910 471.782 1.00 130.63 ? 70  PHE H N   1 
ATOM 526  C CA  . PHE A 1 70  ? 268.870 373.315 471.946 1.00 130.63 ? 70  PHE H CA  1 
ATOM 527  C C   . PHE A 1 70  ? 269.519 373.476 470.580 1.00 130.63 ? 70  PHE H C   1 
ATOM 528  O O   . PHE A 1 70  ? 268.994 373.023 469.561 1.00 130.63 ? 70  PHE H O   1 
ATOM 529  C CB  . PHE A 1 70  ? 269.650 372.298 472.781 1.00 130.63 ? 70  PHE H CB  1 
ATOM 530  C CG  . PHE A 1 70  ? 269.293 372.300 474.242 1.00 130.63 ? 70  PHE H CG  1 
ATOM 531  C CD1 . PHE A 1 70  ? 268.529 373.313 474.795 1.00 130.63 ? 70  PHE H CD1 1 
ATOM 532  C CD2 . PHE A 1 70  ? 269.731 371.282 475.064 1.00 130.63 ? 70  PHE H CD2 1 
ATOM 533  C CE1 . PHE A 1 70  ? 268.204 373.298 476.137 1.00 130.63 ? 70  PHE H CE1 1 
ATOM 534  C CE2 . PHE A 1 70  ? 269.411 371.268 476.407 1.00 130.63 ? 70  PHE H CE2 1 
ATOM 535  C CZ  . PHE A 1 70  ? 268.649 372.277 476.943 1.00 130.63 ? 70  PHE H CZ  1 
ATOM 536  N N   . THR A 1 71  ? 270.669 374.140 470.566 1.00 124.89 ? 71  THR H N   1 
ATOM 537  C CA  . THR A 1 71  ? 271.363 374.419 469.318 1.00 124.89 ? 71  THR H CA  1 
ATOM 538  C C   . THR A 1 71  ? 272.850 374.519 469.596 1.00 124.89 ? 71  THR H C   1 
ATOM 539  O O   . THR A 1 71  ? 273.276 375.360 470.389 1.00 124.89 ? 71  THR H O   1 
ATOM 540  C CB  . THR A 1 71  ? 270.854 375.715 468.683 1.00 124.89 ? 71  THR H CB  1 
ATOM 541  O OG1 . THR A 1 71  ? 269.520 375.520 468.204 1.00 124.89 ? 71  THR H OG1 1 
ATOM 542  C CG2 . THR A 1 71  ? 271.739 376.128 467.527 1.00 124.89 ? 71  THR H CG2 1 
ATOM 543  N N   . ILE A 1 72  ? 273.632 373.664 468.946 1.00 117.06 ? 72  ILE H N   1 
ATOM 544  C CA  . ILE A 1 72  ? 275.077 373.628 469.111 1.00 117.06 ? 72  ILE H CA  1 
ATOM 545  C C   . ILE A 1 72  ? 275.712 374.221 467.866 1.00 117.06 ? 72  ILE H C   1 
ATOM 546  O O   . ILE A 1 72  ? 275.347 373.857 466.744 1.00 117.06 ? 72  ILE H O   1 
ATOM 547  C CB  . ILE A 1 72  ? 275.578 372.198 469.355 1.00 117.06 ? 72  ILE H CB  1 
ATOM 548  C CG1 . ILE A 1 72  ? 274.738 371.531 470.436 1.00 117.06 ? 72  ILE H CG1 1 
ATOM 549  C CG2 . ILE A 1 72  ? 277.031 372.211 469.763 1.00 117.06 ? 72  ILE H CG2 1 
ATOM 550  C CD1 . ILE A 1 72  ? 275.163 370.132 470.752 1.00 117.06 ? 72  ILE H CD1 1 
ATOM 551  N N   . SER A 1 73  ? 276.656 375.136 468.062 1.00 124.35 ? 73  SER H N   1 
ATOM 552  C CA  . SER A 1 73  ? 277.381 375.736 466.953 1.00 124.35 ? 73  SER H CA  1 
ATOM 553  C C   . SER A 1 73  ? 278.726 376.220 467.467 1.00 124.35 ? 73  SER H C   1 
ATOM 554  O O   . SER A 1 73  ? 278.954 376.313 468.673 1.00 124.35 ? 73  SER H O   1 
ATOM 555  C CB  . SER A 1 73  ? 276.591 376.884 466.325 1.00 124.35 ? 73  SER H CB  1 
ATOM 556  O OG  . SER A 1 73  ? 276.017 377.703 467.323 1.00 124.35 ? 73  SER H OG  1 
ATOM 557  N N   . ARG A 1 74  ? 279.614 376.535 466.531 1.00 133.95 ? 74  ARG H N   1 
ATOM 558  C CA  . ARG A 1 74  ? 280.942 377.024 466.854 1.00 133.95 ? 74  ARG H CA  1 
ATOM 559  C C   . ARG A 1 74  ? 281.199 378.318 466.100 1.00 133.95 ? 74  ARG H C   1 
ATOM 560  O O   . ARG A 1 74  ? 280.505 378.652 465.138 1.00 133.95 ? 74  ARG H O   1 
ATOM 561  C CB  . ARG A 1 74  ? 282.017 375.997 466.504 1.00 133.95 ? 74  ARG H CB  1 
ATOM 562  C CG  . ARG A 1 74  ? 282.052 375.647 465.038 1.00 133.95 ? 74  ARG H CG  1 
ATOM 563  C CD  . ARG A 1 74  ? 283.369 374.996 464.666 1.00 133.95 ? 74  ARG H CD  1 
ATOM 564  N NE  . ARG A 1 74  ? 284.486 375.933 464.763 1.00 133.95 ? 74  ARG H NE  1 
ATOM 565  C CZ  . ARG A 1 74  ? 284.890 376.725 463.775 1.00 133.95 ? 74  ARG H CZ  1 
ATOM 566  N NH1 . ARG A 1 74  ? 284.269 376.702 462.604 1.00 133.95 ? 74  ARG H NH1 1 
ATOM 567  N NH2 . ARG A 1 74  ? 285.916 377.545 463.961 1.00 133.95 ? 74  ARG H NH2 1 
ATOM 568  N N   . ASP A 1 75  ? 282.218 379.044 466.541 1.00 142.55 ? 75  ASP H N   1 
ATOM 569  C CA  . ASP A 1 75  ? 282.577 380.317 465.940 1.00 142.55 ? 75  ASP H CA  1 
ATOM 570  C C   . ASP A 1 75  ? 283.776 380.126 465.021 1.00 142.55 ? 75  ASP H C   1 
ATOM 571  O O   . ASP A 1 75  ? 284.728 379.414 465.347 1.00 142.55 ? 75  ASP H O   1 
ATOM 572  C CB  . ASP A 1 75  ? 282.892 381.354 467.018 1.00 142.55 ? 75  ASP H CB  1 
ATOM 573  C CG  . ASP A 1 75  ? 283.257 382.714 466.451 1.00 142.55 ? 75  ASP H CG  1 
ATOM 574  O OD1 . ASP A 1 75  ? 282.878 383.022 465.299 1.00 142.55 ? 75  ASP H OD1 1 
ATOM 575  O OD2 . ASP A 1 75  ? 283.927 383.485 467.167 1.00 142.55 ? 75  ASP H OD2 1 
ATOM 576  N N   . ASN A 1 76  ? 283.727 380.803 463.873 1.00 147.29 ? 76  ASN H N   1 
ATOM 577  C CA  . ASN A 1 76  ? 284.679 380.530 462.802 1.00 147.29 ? 76  ASN H CA  1 
ATOM 578  C C   . ASN A 1 76  ? 286.041 381.153 463.079 1.00 147.29 ? 76  ASN H C   1 
ATOM 579  O O   . ASN A 1 76  ? 287.071 380.609 462.665 1.00 147.29 ? 76  ASN H O   1 
ATOM 580  C CB  . ASN A 1 76  ? 284.124 381.039 461.477 1.00 147.29 ? 76  ASN H CB  1 
ATOM 581  C CG  . ASN A 1 76  ? 283.488 382.403 461.607 1.00 147.29 ? 76  ASN H CG  1 
ATOM 582  O OD1 . ASN A 1 76  ? 282.497 382.571 462.316 1.00 147.29 ? 76  ASN H OD1 1 
ATOM 583  N ND2 . ASN A 1 76  ? 284.061 383.390 460.930 1.00 147.29 ? 76  ASN H ND2 1 
ATOM 584  N N   . SER A 1 77  ? 286.073 382.293 463.767 1.00 147.76 ? 77  SER H N   1 
ATOM 585  C CA  . SER A 1 77  ? 287.328 383.030 463.907 1.00 147.76 ? 77  SER H CA  1 
ATOM 586  C C   . SER A 1 77  ? 288.230 382.408 464.969 1.00 147.76 ? 77  SER H C   1 
ATOM 587  O O   . SER A 1 77  ? 289.322 381.921 464.664 1.00 147.76 ? 77  SER H O   1 
ATOM 588  C CB  . SER A 1 77  ? 287.037 384.498 464.230 1.00 147.76 ? 77  SER H CB  1 
ATOM 589  O OG  . SER A 1 77  ? 288.159 385.106 464.845 1.00 147.76 ? 77  SER H OG  1 
ATOM 590  N N   . GLN A 1 78  ? 287.787 382.407 466.218 1.00 144.49 ? 78  GLN H N   1 
ATOM 591  C CA  . GLN A 1 78  ? 288.585 381.868 467.305 1.00 144.49 ? 78  GLN H CA  1 
ATOM 592  C C   . GLN A 1 78  ? 288.019 380.534 467.770 1.00 144.49 ? 78  GLN H C   1 
ATOM 593  O O   . GLN A 1 78  ? 286.956 380.091 467.332 1.00 144.49 ? 78  GLN H O   1 
ATOM 594  C CB  . GLN A 1 78  ? 288.653 382.854 468.471 1.00 144.49 ? 78  GLN H CB  1 
ATOM 595  C CG  . GLN A 1 78  ? 287.333 383.076 469.168 1.00 144.49 ? 78  GLN H CG  1 
ATOM 596  C CD  . GLN A 1 78  ? 286.638 384.330 468.695 1.00 144.49 ? 78  GLN H CD  1 
ATOM 597  O OE1 . GLN A 1 78  ? 286.599 384.616 467.501 1.00 144.49 ? 78  GLN H OE1 1 
ATOM 598  N NE2 . GLN A 1 78  ? 286.095 385.095 469.632 1.00 144.49 ? 78  GLN H NE2 1 
ATOM 599  N N   . SER A 1 79  ? 288.750 379.892 468.674 1.00 135.98 ? 79  SER H N   1 
ATOM 600  C CA  . SER A 1 79  ? 288.378 378.572 469.172 1.00 135.98 ? 79  SER H CA  1 
ATOM 601  C C   . SER A 1 79  ? 287.419 378.745 470.337 1.00 135.98 ? 79  SER H C   1 
ATOM 602  O O   . SER A 1 79  ? 287.837 378.920 471.481 1.00 135.98 ? 79  SER H O   1 
ATOM 603  C CB  . SER A 1 79  ? 289.615 377.792 469.596 1.00 135.98 ? 79  SER H CB  1 
ATOM 604  O OG  . SER A 1 79  ? 289.918 378.036 470.956 1.00 135.98 ? 79  SER H OG  1 
ATOM 605  N N   . ILE A 1 80  ? 286.120 378.690 470.050 1.00 131.91 ? 80  ILE H N   1 
ATOM 606  C CA  . ILE A 1 80  ? 285.097 378.760 471.083 1.00 131.91 ? 80  ILE H CA  1 
ATOM 607  C C   . ILE A 1 80  ? 283.905 377.937 470.616 1.00 131.91 ? 80  ILE H C   1 
ATOM 608  O O   . ILE A 1 80  ? 283.733 377.670 469.426 1.00 131.91 ? 80  ILE H O   1 
ATOM 609  C CB  . ILE A 1 80  ? 284.715 380.226 471.412 1.00 131.91 ? 80  ILE H CB  1 
ATOM 610  C CG1 . ILE A 1 80  ? 284.367 380.370 472.890 1.00 131.91 ? 80  ILE H CG1 1 
ATOM 611  C CG2 . ILE A 1 80  ? 283.560 380.717 470.572 1.00 131.91 ? 80  ILE H CG2 1 
ATOM 612  C CD1 . ILE A 1 80  ? 284.248 381.804 473.339 1.00 131.91 ? 80  ILE H CD1 1 
ATOM 613  N N   . LEU A 1 81  ? 283.096 377.500 471.575 1.00 126.46 ? 81  LEU H N   1 
ATOM 614  C CA  . LEU A 1 81  ? 281.987 376.600 471.312 1.00 126.46 ? 81  LEU H CA  1 
ATOM 615  C C   . LEU A 1 81  ? 280.751 377.139 472.009 1.00 126.46 ? 81  LEU H C   1 
ATOM 616  O O   . LEU A 1 81  ? 280.844 377.654 473.123 1.00 126.46 ? 81  LEU H O   1 
ATOM 617  C CB  . LEU A 1 81  ? 282.313 375.190 471.804 1.00 126.46 ? 81  LEU H CB  1 
ATOM 618  C CG  . LEU A 1 81  ? 281.311 374.070 471.561 1.00 126.46 ? 81  LEU H CG  1 
ATOM 619  C CD1 . LEU A 1 81  ? 281.170 373.810 470.085 1.00 126.46 ? 81  LEU H CD1 1 
ATOM 620  C CD2 . LEU A 1 81  ? 281.769 372.824 472.274 1.00 126.46 ? 81  LEU H CD2 1 
ATOM 621  N N   . TYR A 1 82  ? 279.599 377.030 471.358 1.00 125.56 ? 82  TYR H N   1 
ATOM 622  C CA  . TYR A 1 82  ? 278.368 377.605 471.875 1.00 125.56 ? 82  TYR H CA  1 
ATOM 623  C C   . TYR A 1 82  ? 277.343 376.525 472.181 1.00 125.56 ? 82  TYR H C   1 
ATOM 624  O O   . TYR A 1 82  ? 277.499 375.360 471.814 1.00 125.56 ? 82  TYR H O   1 
ATOM 625  C CB  . TYR A 1 82  ? 277.780 378.608 470.882 1.00 125.56 ? 82  TYR H CB  1 
ATOM 626  C CG  . TYR A 1 82  ? 278.605 379.853 470.724 1.00 125.56 ? 82  TYR H CG  1 
ATOM 627  C CD1 . TYR A 1 82  ? 279.362 380.338 471.775 1.00 125.56 ? 82  TYR H CD1 1 
ATOM 628  C CD2 . TYR A 1 82  ? 278.628 380.544 469.523 1.00 125.56 ? 82  TYR H CD2 1 
ATOM 629  C CE1 . TYR A 1 82  ? 280.121 381.475 471.637 1.00 125.56 ? 82  TYR H CE1 1 
ATOM 630  C CE2 . TYR A 1 82  ? 279.383 381.682 469.374 1.00 125.56 ? 82  TYR H CE2 1 
ATOM 631  C CZ  . TYR A 1 82  ? 280.127 382.142 470.434 1.00 125.56 ? 82  TYR H CZ  1 
ATOM 632  O OH  . TYR A 1 82  ? 280.884 383.279 470.295 1.00 125.56 ? 82  TYR H OH  1 
ATOM 633  N N   . LEU A 1 83  ? 276.285 376.939 472.874 1.00 126.42 ? 83  LEU H N   1 
ATOM 634  C CA  . LEU A 1 83  ? 275.111 376.100 473.095 1.00 126.42 ? 83  LEU H CA  1 
ATOM 635  C C   . LEU A 1 83  ? 273.942 377.034 473.365 1.00 126.42 ? 83  LEU H C   1 
ATOM 636  O O   . LEU A 1 83  ? 273.874 377.641 474.436 1.00 126.42 ? 83  LEU H O   1 
ATOM 637  C CB  . LEU A 1 83  ? 275.323 375.139 474.253 1.00 126.42 ? 83  LEU H CB  1 
ATOM 638  C CG  . LEU A 1 83  ? 274.092 374.329 474.660 1.00 126.42 ? 83  LEU H CG  1 
ATOM 639  C CD1 . LEU A 1 83  ? 273.577 373.518 473.497 1.00 126.42 ? 83  LEU H CD1 1 
ATOM 640  C CD2 . LEU A 1 83  ? 274.413 373.419 475.819 1.00 126.42 ? 83  LEU H CD2 1 
ATOM 641  N N   . GLN A 1 84  ? 273.036 377.152 472.405 1.00 133.45 ? 84  GLN H N   1 
ATOM 642  C CA  . GLN A 1 84  ? 271.901 378.057 472.503 1.00 133.45 ? 84  GLN H CA  1 
ATOM 643  C C   . GLN A 1 84  ? 270.690 377.286 473.008 1.00 133.45 ? 84  GLN H C   1 
ATOM 644  O O   . GLN A 1 84  ? 270.225 376.356 472.342 1.00 133.45 ? 84  GLN H O   1 
ATOM 645  C CB  . GLN A 1 84  ? 271.601 378.690 471.147 1.00 133.45 ? 84  GLN H CB  1 
ATOM 646  C CG  . GLN A 1 84  ? 270.409 379.614 471.148 1.00 133.45 ? 84  GLN H CG  1 
ATOM 647  C CD  . GLN A 1 84  ? 270.732 380.958 471.743 1.00 133.45 ? 84  GLN H CD  1 
ATOM 648  O OE1 . GLN A 1 84  ? 271.872 381.412 471.688 1.00 133.45 ? 84  GLN H OE1 1 
ATOM 649  N NE2 . GLN A 1 84  ? 269.730 381.607 472.320 1.00 133.45 ? 84  GLN H NE2 1 
ATOM 650  N N   . MET A 1 85  ? 270.181 377.669 474.169 1.00 140.02 ? 85  MET H N   1 
ATOM 651  C CA  . MET A 1 85  ? 269.044 376.996 474.777 1.00 140.02 ? 85  MET H CA  1 
ATOM 652  C C   . MET A 1 85  ? 267.785 377.833 474.611 1.00 140.02 ? 85  MET H C   1 
ATOM 653  O O   . MET A 1 85  ? 267.838 379.064 474.635 1.00 140.02 ? 85  MET H O   1 
ATOM 654  C CB  . MET A 1 85  ? 269.302 376.731 476.257 1.00 140.02 ? 85  MET H CB  1 
ATOM 655  C CG  . MET A 1 85  ? 270.587 375.982 476.515 1.00 140.02 ? 85  MET H CG  1 
ATOM 656  S SD  . MET A 1 85  ? 270.683 375.319 478.183 1.00 140.02 ? 85  MET H SD  1 
ATOM 657  C CE  . MET A 1 85  ? 271.143 376.789 479.083 1.00 140.02 ? 85  MET H CE  1 
ATOM 658  N N   . ASN A 1 86  ? 266.653 377.157 474.436 1.00 139.96 ? 86  ASN H N   1 
ATOM 659  C CA  . ASN A 1 86  ? 265.369 377.823 474.293 1.00 139.96 ? 86  ASN H CA  1 
ATOM 660  C C   . ASN A 1 86  ? 264.290 376.997 474.973 1.00 139.96 ? 86  ASN H C   1 
ATOM 661  O O   . ASN A 1 86  ? 264.373 375.767 475.014 1.00 139.96 ? 86  ASN H O   1 
ATOM 662  C CB  . ASN A 1 86  ? 264.995 378.036 472.824 1.00 139.96 ? 86  ASN H CB  1 
ATOM 663  C CG  . ASN A 1 86  ? 265.862 379.069 472.150 1.00 139.96 ? 86  ASN H CG  1 
ATOM 664  O OD1 . ASN A 1 86  ? 266.343 378.862 471.038 1.00 139.96 ? 86  ASN H OD1 1 
ATOM 665  N ND2 . ASN A 1 86  ? 266.077 380.188 472.825 1.00 139.96 ? 86  ASN H ND2 1 
ATOM 666  N N   . ALA A 1 87  ? 263.282 377.703 475.499 1.00 143.25 ? 87  ALA H N   1 
ATOM 667  C CA  . ALA A 1 87  ? 262.085 377.134 476.127 1.00 143.25 ? 87  ALA H CA  1 
ATOM 668  C C   . ALA A 1 87  ? 262.442 376.203 477.286 1.00 143.25 ? 87  ALA H C   1 
ATOM 669  O O   . ALA A 1 87  ? 262.123 375.013 477.287 1.00 143.25 ? 87  ALA H O   1 
ATOM 670  C CB  . ALA A 1 87  ? 261.202 376.423 475.094 1.00 143.25 ? 87  ALA H CB  1 
ATOM 671  N N   . LEU A 1 88  ? 263.115 376.772 478.278 1.00 143.48 ? 88  LEU H N   1 
ATOM 672  C CA  . LEU A 1 88  ? 263.583 375.990 479.409 1.00 143.48 ? 88  LEU H CA  1 
ATOM 673  C C   . LEU A 1 88  ? 262.427 375.592 480.316 1.00 143.48 ? 88  LEU H C   1 
ATOM 674  O O   . LEU A 1 88  ? 261.495 376.363 480.550 1.00 143.48 ? 88  LEU H O   1 
ATOM 675  C CB  . LEU A 1 88  ? 264.614 376.781 480.206 1.00 143.48 ? 88  LEU H CB  1 
ATOM 676  C CG  . LEU A 1 88  ? 265.928 377.007 479.472 1.00 143.48 ? 88  LEU H CG  1 
ATOM 677  C CD1 . LEU A 1 88  ? 266.797 377.976 480.231 1.00 143.48 ? 88  LEU H CD1 1 
ATOM 678  C CD2 . LEU A 1 88  ? 266.640 375.688 479.292 1.00 143.48 ? 88  LEU H CD2 1 
ATOM 679  N N   . ARG A 1 89  ? 262.495 374.370 480.820 1.00 146.30 ? 89  ARG H N   1 
ATOM 680  C CA  . ARG A 1 89  ? 261.533 373.859 481.782 1.00 146.30 ? 89  ARG H CA  1 
ATOM 681  C C   . ARG A 1 89  ? 262.244 373.601 483.105 1.00 146.30 ? 89  ARG H C   1 
ATOM 682  O O   . ARG A 1 89  ? 263.431 373.887 483.262 1.00 146.30 ? 89  ARG H O   1 
ATOM 683  C CB  . ARG A 1 89  ? 260.851 372.601 481.248 1.00 146.30 ? 89  ARG H CB  1 
ATOM 684  C CG  . ARG A 1 89  ? 260.223 372.784 479.888 1.00 146.30 ? 89  ARG H CG  1 
ATOM 685  C CD  . ARG A 1 89  ? 259.805 371.453 479.310 1.00 146.30 ? 89  ARG H CD  1 
ATOM 686  N NE  . ARG A 1 89  ? 259.626 371.520 477.866 1.00 146.30 ? 89  ARG H NE  1 
ATOM 687  C CZ  . ARG A 1 89  ? 259.381 370.463 477.101 1.00 146.30 ? 89  ARG H CZ  1 
ATOM 688  N NH1 . ARG A 1 89  ? 259.285 369.258 477.646 1.00 146.30 ? 89  ARG H NH1 1 
ATOM 689  N NH2 . ARG A 1 89  ? 259.232 370.610 475.792 1.00 146.30 ? 89  ARG H NH2 1 
ATOM 690  N N   . ALA A 1 90  ? 261.505 373.036 484.060 1.00 146.47 ? 90  ALA H N   1 
ATOM 691  C CA  . ALA A 1 90  ? 262.010 372.906 485.421 1.00 146.47 ? 90  ALA H CA  1 
ATOM 692  C C   . ALA A 1 90  ? 263.037 371.792 485.565 1.00 146.47 ? 90  ALA H C   1 
ATOM 693  O O   . ALA A 1 90  ? 263.824 371.805 486.516 1.00 146.47 ? 90  ALA H O   1 
ATOM 694  C CB  . ALA A 1 90  ? 260.851 372.668 486.387 1.00 146.47 ? 90  ALA H CB  1 
ATOM 695  N N   . GLU A 1 91  ? 263.051 370.830 484.649 1.00 146.21 ? 91  GLU H N   1 
ATOM 696  C CA  . GLU A 1 91  ? 263.944 369.688 484.757 1.00 146.21 ? 91  GLU H CA  1 
ATOM 697  C C   . GLU A 1 91  ? 265.284 369.911 484.075 1.00 146.21 ? 91  GLU H C   1 
ATOM 698  O O   . GLU A 1 91  ? 266.106 368.992 484.049 1.00 146.21 ? 91  GLU H O   1 
ATOM 699  C CB  . GLU A 1 91  ? 263.290 368.424 484.182 1.00 146.21 ? 91  GLU H CB  1 
ATOM 700  C CG  . GLU A 1 91  ? 262.746 368.530 482.758 1.00 146.21 ? 91  GLU H CG  1 
ATOM 701  C CD  . GLU A 1 91  ? 261.348 369.118 482.681 1.00 146.21 ? 91  GLU H CD  1 
ATOM 702  O OE1 . GLU A 1 91  ? 260.814 369.235 481.559 1.00 146.21 ? 91  GLU H OE1 1 
ATOM 703  O OE2 . GLU A 1 91  ? 260.787 369.466 483.742 1.00 146.21 ? 91  GLU H OE2 1 
ATOM 704  N N   . ASP A 1 92  ? 265.531 371.099 483.532 1.00 141.88 ? 92  ASP H N   1 
ATOM 705  C CA  . ASP A 1 92  ? 266.803 371.409 482.901 1.00 141.88 ? 92  ASP H CA  1 
ATOM 706  C C   . ASP A 1 92  ? 267.816 371.984 483.875 1.00 141.88 ? 92  ASP H C   1 
ATOM 707  O O   . ASP A 1 92  ? 268.880 372.439 483.447 1.00 141.88 ? 92  ASP H O   1 
ATOM 708  C CB  . ASP A 1 92  ? 266.594 372.380 481.742 1.00 141.88 ? 92  ASP H CB  1 
ATOM 709  C CG  . ASP A 1 92  ? 265.730 371.795 480.653 1.00 141.88 ? 92  ASP H CG  1 
ATOM 710  O OD1 . ASP A 1 92  ? 265.475 370.575 480.694 1.00 141.88 ? 92  ASP H OD1 1 
ATOM 711  O OD2 . ASP A 1 92  ? 265.310 372.550 479.753 1.00 141.88 ? 92  ASP H OD2 1 
ATOM 712  N N   . SER A 1 93  ? 267.512 371.980 485.168 1.00 140.62 ? 93  SER H N   1 
ATOM 713  C CA  . SER A 1 93  ? 268.451 372.447 486.179 1.00 140.62 ? 93  SER H CA  1 
ATOM 714  C C   . SER A 1 93  ? 269.496 371.363 486.395 1.00 140.62 ? 93  SER H C   1 
ATOM 715  O O   . SER A 1 93  ? 269.206 370.328 487.003 1.00 140.62 ? 93  SER H O   1 
ATOM 716  C CB  . SER A 1 93  ? 267.719 372.770 487.475 1.00 140.62 ? 93  SER H CB  1 
ATOM 717  O OG  . SER A 1 93  ? 267.147 374.063 487.425 1.00 140.62 ? 93  SER H OG  1 
ATOM 718  N N   . ALA A 1 94  ? 270.706 371.593 485.906 1.00 130.04 ? 94  ALA H N   1 
ATOM 719  C CA  . ALA A 1 94  ? 271.730 370.561 485.927 1.00 130.04 ? 94  ALA H CA  1 
ATOM 720  C C   . ALA A 1 94  ? 273.098 371.230 485.897 1.00 130.04 ? 94  ALA H C   1 
ATOM 721  O O   . ALA A 1 94  ? 273.210 372.458 485.938 1.00 130.04 ? 94  ALA H O   1 
ATOM 722  C CB  . ALA A 1 94  ? 271.537 369.596 484.755 1.00 130.04 ? 94  ALA H CB  1 
ATOM 723  N N   . THR A 1 95  ? 274.142 370.412 485.830 1.00 127.80 ? 95  THR H N   1 
ATOM 724  C CA  . THR A 1 95  ? 275.517 370.872 485.707 1.00 127.80 ? 95  THR H CA  1 
ATOM 725  C C   . THR A 1 95  ? 276.038 370.453 484.342 1.00 127.80 ? 95  THR H C   1 
ATOM 726  O O   . THR A 1 95  ? 276.093 369.258 484.038 1.00 127.80 ? 95  THR H O   1 
ATOM 727  C CB  . THR A 1 95  ? 276.386 370.287 486.815 1.00 127.80 ? 95  THR H CB  1 
ATOM 728  O OG1 . THR A 1 95  ? 275.717 370.439 488.071 1.00 127.80 ? 95  THR H OG1 1 
ATOM 729  C CG2 . THR A 1 95  ? 277.719 370.994 486.871 1.00 127.80 ? 95  THR H CG2 1 
ATOM 730  N N   . TYR A 1 96  ? 276.419 371.428 483.526 1.00 124.35 ? 96  TYR H N   1 
ATOM 731  C CA  . TYR A 1 96  ? 276.735 371.199 482.123 1.00 124.35 ? 96  TYR H CA  1 
ATOM 732  C C   . TYR A 1 96  ? 278.244 371.108 481.944 1.00 124.35 ? 96  TYR H C   1 
ATOM 733  O O   . TYR A 1 96  ? 278.981 371.981 482.410 1.00 124.35 ? 96  TYR H O   1 
ATOM 734  C CB  . TYR A 1 96  ? 276.160 372.315 481.256 1.00 124.35 ? 96  TYR H CB  1 
ATOM 735  C CG  . TYR A 1 96  ? 274.667 372.230 481.080 1.00 124.35 ? 96  TYR H CG  1 
ATOM 736  C CD1 . TYR A 1 96  ? 273.805 372.672 482.071 1.00 124.35 ? 96  TYR H CD1 1 
ATOM 737  C CD2 . TYR A 1 96  ? 274.120 371.711 479.923 1.00 124.35 ? 96  TYR H CD2 1 
ATOM 738  C CE1 . TYR A 1 96  ? 272.443 372.594 481.913 1.00 124.35 ? 96  TYR H CE1 1 
ATOM 739  C CE2 . TYR A 1 96  ? 272.760 371.630 479.756 1.00 124.35 ? 96  TYR H CE2 1 
ATOM 740  C CZ  . TYR A 1 96  ? 271.928 372.073 480.753 1.00 124.35 ? 96  TYR H CZ  1 
ATOM 741  O OH  . TYR A 1 96  ? 270.569 371.991 480.587 1.00 124.35 ? 96  TYR H OH  1 
ATOM 742  N N   . TYR A 1 97  ? 278.698 370.060 481.268 1.00 121.32 ? 97  TYR H N   1 
ATOM 743  C CA  . TYR A 1 97  ? 280.104 369.861 480.967 1.00 121.32 ? 97  TYR H CA  1 
ATOM 744  C C   . TYR A 1 97  ? 280.357 370.122 479.492 1.00 121.32 ? 97  TYR H C   1 
ATOM 745  O O   . TYR A 1 97  ? 279.447 370.454 478.737 1.00 121.32 ? 97  TYR H O   1 
ATOM 746  C CB  . TYR A 1 97  ? 280.544 368.447 481.344 1.00 121.32 ? 97  TYR H CB  1 
ATOM 747  C CG  . TYR A 1 97  ? 280.535 368.200 482.826 1.00 121.32 ? 97  TYR H CG  1 
ATOM 748  C CD1 . TYR A 1 97  ? 281.625 368.538 483.607 1.00 121.32 ? 97  TYR H CD1 1 
ATOM 749  C CD2 . TYR A 1 97  ? 279.436 367.633 483.444 1.00 121.32 ? 97  TYR H CD2 1 
ATOM 750  C CE1 . TYR A 1 97  ? 281.622 368.316 484.961 1.00 121.32 ? 97  TYR H CE1 1 
ATOM 751  C CE2 . TYR A 1 97  ? 279.423 367.406 484.795 1.00 121.32 ? 97  TYR H CE2 1 
ATOM 752  C CZ  . TYR A 1 97  ? 280.517 367.749 485.548 1.00 121.32 ? 97  TYR H CZ  1 
ATOM 753  O OH  . TYR A 1 97  ? 280.509 367.526 486.901 1.00 121.32 ? 97  TYR H OH  1 
ATOM 754  N N   . CYS A 1 98  ? 281.613 369.971 479.082 1.00 123.84 ? 98  CYS H N   1 
ATOM 755  C CA  . CYS A 1 98  ? 282.027 370.250 477.707 1.00 123.84 ? 98  CYS H CA  1 
ATOM 756  C C   . CYS A 1 98  ? 283.178 369.309 477.378 1.00 123.84 ? 98  CYS H C   1 
ATOM 757  O O   . CYS A 1 98  ? 284.331 369.608 477.691 1.00 123.84 ? 98  CYS H O   1 
ATOM 758  C CB  . CYS A 1 98  ? 282.435 371.709 477.553 1.00 123.84 ? 98  CYS H CB  1 
ATOM 759  S SG  . CYS A 1 98  ? 283.050 372.192 475.929 1.00 123.84 ? 98  CYS H SG  1 
ATOM 760  N N   . ALA A 1 99  ? 282.871 368.187 476.745 1.00 112.48 ? 99  ALA H N   1 
ATOM 761  C CA  . ALA A 1 99  ? 283.844 367.125 476.544 1.00 112.48 ? 99  ALA H CA  1 
ATOM 762  C C   . ALA A 1 99  ? 284.427 367.158 475.141 1.00 112.48 ? 99  ALA H C   1 
ATOM 763  O O   . ALA A 1 99  ? 283.858 367.752 474.224 1.00 112.48 ? 99  ALA H O   1 
ATOM 764  C CB  . ALA A 1 99  ? 283.211 365.759 476.794 1.00 112.48 ? 99  ALA H CB  1 
ATOM 765  N N   . ARG A 1 100 ? 285.574 366.507 474.983 1.00 107.04 ? 100 ARG H N   1 
ATOM 766  C CA  . ARG A 1 100 ? 286.226 366.326 473.698 1.00 107.04 ? 100 ARG H CA  1 
ATOM 767  C C   . ARG A 1 100 ? 286.206 364.852 473.322 1.00 107.04 ? 100 ARG H C   1 
ATOM 768  O O   . ARG A 1 100 ? 286.044 363.979 474.173 1.00 107.04 ? 100 ARG H O   1 
ATOM 769  C CB  . ARG A 1 100 ? 287.667 366.836 473.744 1.00 107.04 ? 100 ARG H CB  1 
ATOM 770  C CG  . ARG A 1 100 ? 288.211 367.298 472.418 1.00 107.04 ? 100 ARG H CG  1 
ATOM 771  C CD  . ARG A 1 100 ? 289.720 367.385 472.440 1.00 107.04 ? 100 ARG H CD  1 
ATOM 772  N NE  . ARG A 1 100 ? 290.335 366.132 472.856 1.00 107.04 ? 100 ARG H NE  1 
ATOM 773  C CZ  . ARG A 1 100 ? 291.631 365.871 472.743 1.00 107.04 ? 100 ARG H CZ  1 
ATOM 774  N NH1 . ARG A 1 100 ? 292.441 366.773 472.218 1.00 107.04 ? 100 ARG H NH1 1 
ATOM 775  N NH2 . ARG A 1 100 ? 292.114 364.708 473.148 1.00 107.04 ? 100 ARG H NH2 1 
ATOM 776  N N   . SER A 1 101 ? 286.356 364.577 472.033 1.00 103.69 ? 101 SER H N   1 
ATOM 777  C CA  . SER A 1 101 ? 286.497 363.218 471.540 1.00 103.69 ? 101 SER H CA  1 
ATOM 778  C C   . SER A 1 101 ? 287.761 363.131 470.702 1.00 103.69 ? 101 SER H C   1 
ATOM 779  O O   . SER A 1 101 ? 288.340 364.148 470.319 1.00 103.69 ? 101 SER H O   1 
ATOM 780  C CB  . SER A 1 101 ? 285.293 362.787 470.711 1.00 103.69 ? 101 SER H CB  1 
ATOM 781  O OG  . SER A 1 101 ? 284.170 362.568 471.535 1.00 103.69 ? 101 SER H OG  1 
ATOM 782  N N   . ARG A 1 102 ? 288.187 361.908 470.411 0.00 102.92 ? 102 ARG H N   1 
ATOM 783  C CA  . ARG A 1 102 ? 289.409 361.722 469.646 0.00 102.92 ? 102 ARG H CA  1 
ATOM 784  C C   . ARG A 1 102 ? 289.363 360.388 468.923 0.00 102.92 ? 102 ARG H C   1 
ATOM 785  O O   . ARG A 1 102 ? 288.565 359.507 469.244 0.00 102.92 ? 102 ARG H O   1 
ATOM 786  C CB  . ARG A 1 102 ? 290.640 361.800 470.546 0.00 102.92 ? 102 ARG H CB  1 
ATOM 787  C CG  . ARG A 1 102 ? 290.597 360.836 471.703 0.00 102.92 ? 102 ARG H CG  1 
ATOM 788  C CD  . ARG A 1 102 ? 291.990 360.542 472.224 0.00 102.92 ? 102 ARG H CD  1 
ATOM 789  N NE  . ARG A 1 102 ? 292.863 360.006 471.187 0.00 102.92 ? 102 ARG H NE  1 
ATOM 790  C CZ  . ARG A 1 102 ? 293.992 359.352 471.433 0.00 102.92 ? 102 ARG H CZ  1 
ATOM 791  N NH1 . ARG A 1 102 ? 294.381 359.150 472.681 0.00 102.92 ? 102 ARG H NH1 1 
ATOM 792  N NH2 . ARG A 1 102 ? 294.728 358.896 470.431 0.00 102.92 ? 102 ARG H NH2 1 
ATOM 793  N N   . TYR A 1 103 ? 290.244 360.252 467.938 1.00 99.02  ? 103 TYR H N   1 
ATOM 794  C CA  . TYR A 1 103 ? 290.400 359.017 467.188 1.00 99.02  ? 103 TYR H CA  1 
ATOM 795  C C   . TYR A 1 103 ? 291.444 358.147 467.870 1.00 99.02  ? 103 TYR H C   1 
ATOM 796  O O   . TYR A 1 103 ? 292.577 358.588 468.085 1.00 99.02  ? 103 TYR H O   1 
ATOM 797  C CB  . TYR A 1 103 ? 290.828 359.314 465.753 1.00 99.02  ? 103 TYR H CB  1 
ATOM 798  C CG  . TYR A 1 103 ? 289.728 359.836 464.869 1.00 99.02  ? 103 TYR H CG  1 
ATOM 799  C CD1 . TYR A 1 103 ? 289.385 361.175 464.873 1.00 99.02  ? 103 TYR H CD1 1 
ATOM 800  C CD2 . TYR A 1 103 ? 289.041 358.985 464.019 1.00 99.02  ? 103 TYR H CD2 1 
ATOM 801  C CE1 . TYR A 1 103 ? 288.385 361.650 464.063 1.00 99.02  ? 103 TYR H CE1 1 
ATOM 802  C CE2 . TYR A 1 103 ? 288.041 359.452 463.206 1.00 99.02  ? 103 TYR H CE2 1 
ATOM 803  C CZ  . TYR A 1 103 ? 287.718 360.783 463.233 1.00 99.02  ? 103 TYR H CZ  1 
ATOM 804  O OH  . TYR A 1 103 ? 286.718 361.246 462.420 1.00 99.02  ? 103 TYR H OH  1 
ATOM 805  N N   . TYR A 1 104 ? 291.070 356.916 468.206 1.00 103.60 ? 104 TYR H N   1 
ATOM 806  C CA  . TYR A 1 104 ? 291.991 356.035 468.915 1.00 103.60 ? 104 TYR H CA  1 
ATOM 807  C C   . TYR A 1 104 ? 292.861 355.233 467.956 1.00 103.60 ? 104 TYR H C   1 
ATOM 808  O O   . TYR A 1 104 ? 294.092 355.295 468.025 1.00 103.60 ? 104 TYR H O   1 
ATOM 809  C CB  . TYR A 1 104 ? 291.214 355.125 469.860 1.00 103.60 ? 104 TYR H CB  1 
ATOM 810  C CG  . TYR A 1 104 ? 290.807 355.874 471.089 1.00 103.60 ? 104 TYR H CG  1 
ATOM 811  C CD1 . TYR A 1 104 ? 291.762 356.331 471.980 1.00 103.60 ? 104 TYR H CD1 1 
ATOM 812  C CD2 . TYR A 1 104 ? 289.478 356.158 471.343 1.00 103.60 ? 104 TYR H CD2 1 
ATOM 813  C CE1 . TYR A 1 104 ? 291.407 357.032 473.100 1.00 103.60 ? 104 TYR H CE1 1 
ATOM 814  C CE2 . TYR A 1 104 ? 289.110 356.860 472.464 1.00 103.60 ? 104 TYR H CE2 1 
ATOM 815  C CZ  . TYR A 1 104 ? 290.080 357.292 473.337 1.00 103.60 ? 104 TYR H CZ  1 
ATOM 816  O OH  . TYR A 1 104 ? 289.724 357.994 474.456 1.00 103.60 ? 104 TYR H OH  1 
ATOM 817  N N   . GLY A 1 105 ? 292.246 354.481 467.059 1.00 102.43 ? 105 GLY H N   1 
ATOM 818  C CA  . GLY A 1 105 ? 292.999 353.938 465.952 1.00 102.43 ? 105 GLY H CA  1 
ATOM 819  C C   . GLY A 1 105 ? 292.974 354.963 464.844 1.00 102.43 ? 105 GLY H C   1 
ATOM 820  O O   . GLY A 1 105 ? 293.441 356.091 465.016 1.00 102.43 ? 105 GLY H O   1 
ATOM 821  N N   . GLY A 1 106 ? 292.437 354.581 463.698 1.00 101.97 ? 106 GLY H N   1 
ATOM 822  C CA  . GLY A 1 106 ? 291.976 355.568 462.749 1.00 101.97 ? 106 GLY H CA  1 
ATOM 823  C C   . GLY A 1 106 ? 290.471 355.583 462.842 1.00 101.97 ? 106 GLY H C   1 
ATOM 824  O O   . GLY A 1 106 ? 289.787 356.351 462.161 1.00 101.97 ? 106 GLY H O   1 
ATOM 825  N N   . THR A 1 107 ? 289.951 354.717 463.701 1.00 100.29 ? 107 THR H N   1 
ATOM 826  C CA  . THR A 1 107 ? 288.528 354.574 463.922 1.00 100.29 ? 107 THR H CA  1 
ATOM 827  C C   . THR A 1 107 ? 288.066 355.599 464.944 1.00 100.29 ? 107 THR H C   1 
ATOM 828  O O   . THR A 1 107 ? 288.861 356.205 465.662 1.00 100.29 ? 107 THR H O   1 
ATOM 829  C CB  . THR A 1 107 ? 288.204 353.162 464.397 1.00 100.29 ? 107 THR H CB  1 
ATOM 830  O OG1 . THR A 1 107 ? 289.028 352.847 465.523 1.00 100.29 ? 107 THR H OG1 1 
ATOM 831  C CG2 . THR A 1 107 ? 288.481 352.167 463.303 1.00 100.29 ? 107 THR H CG2 1 
ATOM 832  N N   . TYR A 1 108 ? 286.758 355.786 465.015 0.00 101.45 ? 108 TYR H N   1 
ATOM 833  C CA  . TYR A 1 108 ? 286.158 356.685 465.991 0.00 101.45 ? 108 TYR H CA  1 
ATOM 834  C C   . TYR A 1 108 ? 285.334 355.852 466.958 0.00 101.45 ? 108 TYR H C   1 
ATOM 835  O O   . TYR A 1 108 ? 284.158 355.584 466.710 0.00 101.45 ? 108 TYR H O   1 
ATOM 836  C CB  . TYR A 1 108 ? 285.298 357.746 465.327 0.00 101.45 ? 108 TYR H CB  1 
ATOM 837  C CG  . TYR A 1 108 ? 284.636 358.658 466.322 0.00 101.45 ? 108 TYR H CG  1 
ATOM 838  C CD1 . TYR A 1 108 ? 285.388 359.490 467.126 0.00 101.45 ? 108 TYR H CD1 1 
ATOM 839  C CD2 . TYR A 1 108 ? 283.264 358.680 466.464 0.00 101.45 ? 108 TYR H CD2 1 
ATOM 840  C CE1 . TYR A 1 108 ? 284.792 360.323 468.038 0.00 101.45 ? 108 TYR H CE1 1 
ATOM 841  C CE2 . TYR A 1 108 ? 282.658 359.511 467.376 0.00 101.45 ? 108 TYR H CE2 1 
ATOM 842  C CZ  . TYR A 1 108 ? 283.428 360.331 468.158 0.00 101.45 ? 108 TYR H CZ  1 
ATOM 843  O OH  . TYR A 1 108 ? 282.830 361.160 469.071 0.00 101.45 ? 108 TYR H OH  1 
ATOM 844  N N   . ARG A 1 109 ? 285.953 355.435 468.051 0.00 102.07 ? 109 ARG H N   1 
ATOM 845  C CA  . ARG A 1 109 ? 285.193 354.964 469.189 0.00 102.07 ? 109 ARG H CA  1 
ATOM 846  C C   . ARG A 1 109 ? 284.521 356.168 469.826 0.00 102.07 ? 109 ARG H C   1 
ATOM 847  O O   . ARG A 1 109 ? 284.963 357.306 469.656 0.00 102.07 ? 109 ARG H O   1 
ATOM 848  C CB  . ARG A 1 109 ? 286.094 354.261 470.200 0.00 102.07 ? 109 ARG H CB  1 
ATOM 849  C CG  . ARG A 1 109 ? 286.638 352.924 469.737 0.00 102.07 ? 109 ARG H CG  1 
ATOM 850  C CD  . ARG A 1 109 ? 287.997 353.079 469.093 0.00 102.07 ? 109 ARG H CD  1 
ATOM 851  N NE  . ARG A 1 109 ? 288.505 351.830 468.553 0.00 102.07 ? 109 ARG H NE  1 
ATOM 852  C CZ  . ARG A 1 109 ? 289.390 351.069 469.175 0.00 102.07 ? 109 ARG H CZ  1 
ATOM 853  N NH1 . ARG A 1 109 ? 289.811 349.948 468.619 0.00 102.07 ? 109 ARG H NH1 1 
ATOM 854  N NH2 . ARG A 1 109 ? 289.852 351.433 470.355 0.00 102.07 ? 109 ARG H NH2 1 
ATOM 855  N N   . TYR A 1 110 ? 283.450 355.923 470.568 0.00 101.91 ? 110 TYR H N   1 
ATOM 856  C CA  . TYR A 1 110 ? 282.622 357.022 471.044 0.00 101.91 ? 110 TYR H CA  1 
ATOM 857  C C   . TYR A 1 110 ? 282.981 357.470 472.451 0.00 101.91 ? 110 TYR H C   1 
ATOM 858  O O   . TYR A 1 110 ? 282.095 357.851 473.219 0.00 101.91 ? 110 TYR H O   1 
ATOM 859  C CB  . TYR A 1 110 ? 281.152 356.637 470.953 0.00 101.91 ? 110 TYR H CB  1 
ATOM 860  C CG  . TYR A 1 110 ? 280.621 356.726 469.551 0.00 101.91 ? 110 TYR H CG  1 
ATOM 861  C CD1 . TYR A 1 110 ? 280.826 355.700 468.648 0.00 101.91 ? 110 TYR H CD1 1 
ATOM 862  C CD2 . TYR A 1 110 ? 279.921 357.839 469.126 0.00 101.91 ? 110 TYR H CD2 1 
ATOM 863  C CE1 . TYR A 1 110 ? 280.349 355.779 467.360 0.00 101.91 ? 110 TYR H CE1 1 
ATOM 864  C CE2 . TYR A 1 110 ? 279.436 357.922 467.840 0.00 101.91 ? 110 TYR H CE2 1 
ATOM 865  C CZ  . TYR A 1 110 ? 279.653 356.888 466.966 0.00 101.91 ? 110 TYR H CZ  1 
ATOM 866  O OH  . TYR A 1 110 ? 279.179 356.961 465.685 0.00 101.91 ? 110 TYR H OH  1 
ATOM 867  N N   . ALA A 1 111 ? 284.258 357.438 472.810 0.67 101.40 ? 111 ALA H N   1 
ATOM 868  C CA  . ALA A 1 111 ? 284.683 357.847 474.135 0.67 101.40 ? 111 ALA H CA  1 
ATOM 869  C C   . ALA A 1 111 ? 284.804 359.361 474.227 0.67 101.40 ? 111 ALA H C   1 
ATOM 870  O O   . ALA A 1 111 ? 284.845 360.068 473.220 0.67 101.40 ? 111 ALA H O   1 
ATOM 871  C CB  . ALA A 1 111 ? 286.019 357.204 474.489 0.67 101.40 ? 111 ALA H CB  1 
ATOM 872  N N   . LEU A 1 112 ? 284.878 359.854 475.461 1.00 108.66 ? 112 LEU H N   1 
ATOM 873  C CA  . LEU A 1 112 ? 285.000 361.279 475.768 1.00 108.66 ? 112 LEU H CA  1 
ATOM 874  C C   . LEU A 1 112 ? 286.154 361.431 476.753 1.00 108.66 ? 112 LEU H C   1 
ATOM 875  O O   . LEU A 1 112 ? 285.987 361.155 477.940 1.00 108.66 ? 112 LEU H O   1 
ATOM 876  C CB  . LEU A 1 112 ? 283.714 361.824 476.365 1.00 108.66 ? 112 LEU H CB  1 
ATOM 877  C CG  . LEU A 1 112 ? 282.381 361.510 475.691 1.00 108.66 ? 112 LEU H CG  1 
ATOM 878  C CD1 . LEU A 1 112 ? 281.237 362.118 476.469 1.00 108.66 ? 112 LEU H CD1 1 
ATOM 879  C CD2 . LEU A 1 112 ? 282.366 362.006 474.282 1.00 108.66 ? 112 LEU H CD2 1 
ATOM 880  N N   . ASP A 1 113 ? 287.317 361.883 476.284 1.00 112.87 ? 113 ASP H N   1 
ATOM 881  C CA  . ASP A 1 113 ? 288.489 361.840 477.155 1.00 112.87 ? 113 ASP H CA  1 
ATOM 882  C C   . ASP A 1 113 ? 288.589 363.064 478.063 1.00 112.87 ? 113 ASP H C   1 
ATOM 883  O O   . ASP A 1 113 ? 288.596 362.933 479.290 1.00 112.87 ? 113 ASP H O   1 
ATOM 884  C CB  . ASP A 1 113 ? 289.765 361.676 476.330 1.00 112.87 ? 113 ASP H CB  1 
ATOM 885  C CG  . ASP A 1 113 ? 289.779 362.543 475.113 1.00 112.87 ? 113 ASP H CG  1 
ATOM 886  O OD1 . ASP A 1 113 ? 288.723 363.122 474.805 1.00 112.87 ? 113 ASP H OD1 1 
ATOM 887  O OD2 . ASP A 1 113 ? 290.843 362.665 474.476 1.00 112.87 ? 113 ASP H OD2 1 
ATOM 888  N N   . TYR A 1 114 ? 288.670 364.260 477.489 1.00 116.00 ? 114 TYR H N   1 
ATOM 889  C CA  . TYR A 1 114 ? 288.954 365.468 478.251 1.00 116.00 ? 114 TYR H CA  1 
ATOM 890  C C   . TYR A 1 114 ? 287.665 366.226 478.523 1.00 116.00 ? 114 TYR H C   1 
ATOM 891  O O   . TYR A 1 114 ? 286.941 366.580 477.589 1.00 116.00 ? 114 TYR H O   1 
ATOM 892  C CB  . TYR A 1 114 ? 289.942 366.355 477.504 1.00 116.00 ? 114 TYR H CB  1 
ATOM 893  C CG  . TYR A 1 114 ? 291.341 365.818 477.537 1.00 116.00 ? 114 TYR H CG  1 
ATOM 894  C CD1 . TYR A 1 114 ? 292.183 366.094 478.602 1.00 116.00 ? 114 TYR H CD1 1 
ATOM 895  C CD2 . TYR A 1 114 ? 291.816 365.018 476.513 1.00 116.00 ? 114 TYR H CD2 1 
ATOM 896  C CE1 . TYR A 1 114 ? 293.469 365.601 478.637 1.00 116.00 ? 114 TYR H CE1 1 
ATOM 897  C CE2 . TYR A 1 114 ? 293.099 364.516 476.540 1.00 116.00 ? 114 TYR H CE2 1 
ATOM 898  C CZ  . TYR A 1 114 ? 293.920 364.812 477.603 1.00 116.00 ? 114 TYR H CZ  1 
ATOM 899  O OH  . TYR A 1 114 ? 295.200 364.315 477.632 1.00 116.00 ? 114 TYR H OH  1 
ATOM 900  N N   . TRP A 1 115 ? 287.392 366.488 479.794 1.00 114.86 ? 115 TRP H N   1 
ATOM 901  C CA  . TRP A 1 115 ? 286.165 367.139 480.215 1.00 114.86 ? 115 TRP H CA  1 
ATOM 902  C C   . TRP A 1 115 ? 286.475 368.513 480.789 1.00 114.86 ? 115 TRP H C   1 
ATOM 903  O O   . TRP A 1 115 ? 287.556 368.756 481.327 1.00 114.86 ? 115 TRP H O   1 
ATOM 904  C CB  . TRP A 1 115 ? 285.430 366.300 481.263 1.00 114.86 ? 115 TRP H CB  1 
ATOM 905  C CG  . TRP A 1 115 ? 284.933 364.975 480.778 1.00 114.86 ? 115 TRP H CG  1 
ATOM 906  C CD1 . TRP A 1 115 ? 285.683 363.934 480.329 1.00 114.86 ? 115 TRP H CD1 1 
ATOM 907  C CD2 . TRP A 1 115 ? 283.573 364.540 480.724 1.00 114.86 ? 115 TRP H CD2 1 
ATOM 908  N NE1 . TRP A 1 115 ? 284.876 362.884 479.982 1.00 114.86 ? 115 TRP H NE1 1 
ATOM 909  C CE2 . TRP A 1 115 ? 283.574 363.231 480.220 1.00 114.86 ? 115 TRP H CE2 1 
ATOM 910  C CE3 . TRP A 1 115 ? 282.356 365.132 481.048 1.00 114.86 ? 115 TRP H CE3 1 
ATOM 911  C CZ2 . TRP A 1 115 ? 282.410 362.508 480.032 1.00 114.86 ? 115 TRP H CZ2 1 
ATOM 912  C CZ3 . TRP A 1 115 ? 281.202 364.411 480.860 1.00 114.86 ? 115 TRP H CZ3 1 
ATOM 913  C CH2 . TRP A 1 115 ? 281.235 363.115 480.358 1.00 114.86 ? 115 TRP H CH2 1 
ATOM 914  N N   . GLY A 1 116 ? 285.508 369.416 480.671 1.00 124.17 ? 116 GLY H N   1 
ATOM 915  C CA  . GLY A 1 116 ? 285.630 370.724 481.276 1.00 124.17 ? 116 GLY H CA  1 
ATOM 916  C C   . GLY A 1 116 ? 285.326 370.684 482.757 1.00 124.17 ? 116 GLY H C   1 
ATOM 917  O O   . GLY A 1 116 ? 284.921 369.664 483.302 1.00 124.17 ? 116 GLY H O   1 
ATOM 918  N N   . GLN A 1 117 ? 285.520 371.826 483.414 1.00 132.48 ? 117 GLN H N   1 
ATOM 919  C CA  . GLN A 1 117 ? 285.344 371.867 484.860 1.00 132.48 ? 117 GLN H CA  1 
ATOM 920  C C   . GLN A 1 117 ? 283.881 371.902 485.278 1.00 132.48 ? 117 GLN H C   1 
ATOM 921  O O   . GLN A 1 117 ? 283.583 371.658 486.451 1.00 132.48 ? 117 GLN H O   1 
ATOM 922  C CB  . GLN A 1 117 ? 286.081 373.070 485.454 1.00 132.48 ? 117 GLN H CB  1 
ATOM 923  C CG  . GLN A 1 117 ? 285.293 374.370 485.453 1.00 132.48 ? 117 GLN H CG  1 
ATOM 924  C CD  . GLN A 1 117 ? 285.451 375.164 484.173 1.00 132.48 ? 117 GLN H CD  1 
ATOM 925  O OE1 . GLN A 1 117 ? 285.298 374.636 483.073 1.00 132.48 ? 117 GLN H OE1 1 
ATOM 926  N NE2 . GLN A 1 117 ? 285.754 376.448 484.313 1.00 132.48 ? 117 GLN H NE2 1 
ATOM 927  N N   . GLY A 1 118 ? 282.966 372.197 484.361 1.00 129.86 ? 118 GLY H N   1 
ATOM 928  C CA  . GLY A 1 118 ? 281.556 372.134 484.684 1.00 129.86 ? 118 GLY H CA  1 
ATOM 929  C C   . GLY A 1 118 ? 280.960 373.451 485.129 1.00 129.86 ? 118 GLY H C   1 
ATOM 930  O O   . GLY A 1 118 ? 281.376 374.013 486.143 1.00 129.86 ? 118 GLY H O   1 
ATOM 931  N N   . THR A 1 119 ? 279.993 373.954 484.375 1.00 131.38 ? 119 THR H N   1 
ATOM 932  C CA  . THR A 1 119 ? 279.202 375.102 484.783 1.00 131.38 ? 119 THR H CA  1 
ATOM 933  C C   . THR A 1 119 ? 277.810 374.653 485.202 1.00 131.38 ? 119 THR H C   1 
ATOM 934  O O   . THR A 1 119 ? 277.337 373.580 484.825 1.00 131.38 ? 119 THR H O   1 
ATOM 935  C CB  . THR A 1 119 ? 279.095 376.130 483.660 1.00 131.38 ? 119 THR H CB  1 
ATOM 936  O OG1 . THR A 1 119 ? 278.165 377.150 484.040 1.00 131.38 ? 119 THR H OG1 1 
ATOM 937  C CG2 . THR A 1 119 ? 278.617 375.472 482.390 1.00 131.38 ? 119 THR H CG2 1 
ATOM 938  N N   . SER A 1 120 ? 277.152 375.495 485.989 1.00 132.94 ? 120 SER H N   1 
ATOM 939  C CA  . SER A 1 120 ? 275.859 375.168 486.569 1.00 132.94 ? 120 SER H CA  1 
ATOM 940  C C   . SER A 1 120 ? 274.795 376.116 486.042 1.00 132.94 ? 120 SER H C   1 
ATOM 941  O O   . SER A 1 120 ? 275.048 377.309 485.858 1.00 132.94 ? 120 SER H O   1 
ATOM 942  C CB  . SER A 1 120 ? 275.902 375.246 488.091 1.00 132.94 ? 120 SER H CB  1 
ATOM 943  O OG  . SER A 1 120 ? 274.599 375.416 488.614 1.00 132.94 ? 120 SER H OG  1 
ATOM 944  N N   . VAL A 1 121 ? 273.607 375.576 485.797 1.00 134.79 ? 121 VAL H N   1 
ATOM 945  C CA  . VAL A 1 121 ? 272.451 376.345 485.356 1.00 134.79 ? 121 VAL H CA  1 
ATOM 946  C C   . VAL A 1 121 ? 271.252 375.876 486.162 1.00 134.79 ? 121 VAL H C   1 
ATOM 947  O O   . VAL A 1 121 ? 270.956 374.677 486.197 1.00 134.79 ? 121 VAL H O   1 
ATOM 948  C CB  . VAL A 1 121 ? 272.198 376.182 483.846 1.00 134.79 ? 121 VAL H CB  1 
ATOM 949  C CG1 . VAL A 1 121 ? 270.789 376.602 483.481 1.00 134.79 ? 121 VAL H CG1 1 
ATOM 950  C CG2 . VAL A 1 121 ? 273.190 376.996 483.053 1.00 134.79 ? 121 VAL H CG2 1 
ATOM 951  N N   . THR A 1 122 ? 270.580 376.811 486.828 1.00 143.22 ? 122 THR H N   1 
ATOM 952  C CA  . THR A 1 122 ? 269.367 376.513 487.577 1.00 143.22 ? 122 THR H CA  1 
ATOM 953  C C   . THR A 1 122 ? 268.212 377.316 486.996 1.00 143.22 ? 122 THR H C   1 
ATOM 954  O O   . THR A 1 122 ? 268.426 378.353 486.358 1.00 143.22 ? 122 THR H O   1 
ATOM 955  C CB  . THR A 1 122 ? 269.546 376.801 489.072 1.00 143.22 ? 122 THR H CB  1 
ATOM 956  O OG1 . THR A 1 122 ? 268.456 376.225 489.801 1.00 143.22 ? 122 THR H OG1 1 
ATOM 957  C CG2 . THR A 1 122 ? 269.617 378.293 489.360 1.00 143.22 ? 122 THR H CG2 1 
ATOM 958  N N   . VAL A 1 123 ? 266.999 376.800 487.157 1.00 149.88 ? 123 VAL H N   1 
ATOM 959  C CA  . VAL A 1 123 ? 265.777 377.516 486.812 1.00 149.88 ? 123 VAL H CA  1 
ATOM 960  C C   . VAL A 1 123 ? 264.862 377.483 488.028 1.00 149.88 ? 123 VAL H C   1 
ATOM 961  O O   . VAL A 1 123 ? 264.999 376.606 488.890 1.00 149.88 ? 123 VAL H O   1 
ATOM 962  C CB  . VAL A 1 123 ? 265.073 376.927 485.578 1.00 149.88 ? 123 VAL H CB  1 
ATOM 963  C CG1 . VAL A 1 123 ? 265.980 376.961 484.361 1.00 149.88 ? 123 VAL H CG1 1 
ATOM 964  C CG2 . VAL A 1 123 ? 264.620 375.519 485.850 1.00 149.88 ? 123 VAL H CG2 1 
ATOM 965  N N   . SER A 1 124 ? 263.950 378.444 488.104 1.00 150.67 ? 124 SER H N   1 
ATOM 966  C CA  . SER A 1 124 ? 263.045 378.557 489.239 1.00 150.67 ? 124 SER H CA  1 
ATOM 967  C C   . SER A 1 124 ? 261.813 379.367 488.867 1.00 150.67 ? 124 SER H C   1 
ATOM 968  O O   . SER A 1 124 ? 261.913 380.559 488.580 1.00 150.67 ? 124 SER H O   1 
ATOM 969  C CB  . SER A 1 124 ? 263.754 379.204 490.429 1.00 150.67 ? 124 SER H CB  1 
ATOM 970  O OG  . SER A 1 124 ? 264.512 380.324 490.012 1.00 150.67 ? 124 SER H OG  1 
ATOM 971  N N   . ASN B 2 2   ? 267.828 351.430 474.426 1.00 115.60 ? 2   ASN L N   1 
ATOM 972  C CA  . ASN B 2 2   ? 268.808 350.602 475.115 1.00 115.60 ? 2   ASN L CA  1 
ATOM 973  C C   . ASN B 2 2   ? 269.214 351.237 476.434 1.00 115.60 ? 2   ASN L C   1 
ATOM 974  O O   . ASN B 2 2   ? 269.541 352.419 476.480 1.00 115.60 ? 2   ASN L O   1 
ATOM 975  C CB  . ASN B 2 2   ? 270.036 350.390 474.236 1.00 115.60 ? 2   ASN L CB  1 
ATOM 976  C CG  . ASN B 2 2   ? 270.911 349.270 474.731 1.00 115.60 ? 2   ASN L CG  1 
ATOM 977  O OD1 . ASN B 2 2   ? 270.477 348.429 475.514 1.00 115.60 ? 2   ASN L OD1 1 
ATOM 978  N ND2 . ASN B 2 2   ? 272.152 349.244 474.270 1.00 115.60 ? 2   ASN L ND2 1 
ATOM 979  N N   . VAL B 2 3   ? 269.189 350.458 477.511 1.00 121.17 ? 3   VAL L N   1 
ATOM 980  C CA  . VAL B 2 3   ? 269.513 350.948 478.846 1.00 121.17 ? 3   VAL L CA  1 
ATOM 981  C C   . VAL B 2 3   ? 270.608 350.083 479.452 1.00 121.17 ? 3   VAL L C   1 
ATOM 982  O O   . VAL B 2 3   ? 270.715 348.890 479.145 1.00 121.17 ? 3   VAL L O   1 
ATOM 983  C CB  . VAL B 2 3   ? 268.269 350.977 479.750 1.00 121.17 ? 3   VAL L CB  1 
ATOM 984  C CG1 . VAL B 2 3   ? 267.289 352.027 479.273 1.00 121.17 ? 3   VAL L CG1 1 
ATOM 985  C CG2 . VAL B 2 3   ? 267.594 349.617 479.769 1.00 121.17 ? 3   VAL L CG2 1 
ATOM 986  N N   . LEU B 2 4   ? 271.432 350.690 480.295 1.00 120.61 ? 4   LEU L N   1 
ATOM 987  C CA  . LEU B 2 4   ? 272.455 349.984 481.048 1.00 120.61 ? 4   LEU L CA  1 
ATOM 988  C C   . LEU B 2 4   ? 272.066 349.932 482.516 1.00 120.61 ? 4   LEU L C   1 
ATOM 989  O O   . LEU B 2 4   ? 271.699 350.951 483.107 1.00 120.61 ? 4   LEU L O   1 
ATOM 990  C CB  . LEU B 2 4   ? 273.808 350.669 480.910 1.00 120.61 ? 4   LEU L CB  1 
ATOM 991  C CG  . LEU B 2 4   ? 274.512 350.468 479.581 1.00 120.61 ? 4   LEU L CG  1 
ATOM 992  C CD1 . LEU B 2 4   ? 275.751 351.318 479.544 1.00 120.61 ? 4   LEU L CD1 1 
ATOM 993  C CD2 . LEU B 2 4   ? 274.867 349.024 479.424 1.00 120.61 ? 4   LEU L CD2 1 
ATOM 994  N N   . THR B 2 5   ? 272.147 348.744 483.104 1.00 127.15 ? 5   THR L N   1 
ATOM 995  C CA  . THR B 2 5   ? 271.888 348.563 484.528 1.00 127.15 ? 5   THR L CA  1 
ATOM 996  C C   . THR B 2 5   ? 273.166 348.052 485.171 1.00 127.15 ? 5   THR L C   1 
ATOM 997  O O   . THR B 2 5   ? 273.631 346.957 484.846 1.00 127.15 ? 5   THR L O   1 
ATOM 998  C CB  . THR B 2 5   ? 270.740 347.586 484.780 1.00 127.15 ? 5   THR L CB  1 
ATOM 999  O OG1 . THR B 2 5   ? 271.223 346.244 484.653 1.00 127.15 ? 5   THR L OG1 1 
ATOM 1000 C CG2 . THR B 2 5   ? 269.602 347.806 483.796 1.00 127.15 ? 5   THR L CG2 1 
ATOM 1001 N N   . GLN B 2 6   ? 273.729 348.836 486.077 1.00 125.09 ? 6   GLN L N   1 
ATOM 1002 C CA  . GLN B 2 6   ? 274.901 348.428 486.832 1.00 125.09 ? 6   GLN L CA  1 
ATOM 1003 C C   . GLN B 2 6   ? 274.462 347.760 488.124 1.00 125.09 ? 6   GLN L C   1 
ATOM 1004 O O   . GLN B 2 6   ? 273.361 348.009 488.620 1.00 125.09 ? 6   GLN L O   1 
ATOM 1005 C CB  . GLN B 2 6   ? 275.796 349.620 487.147 1.00 125.09 ? 6   GLN L CB  1 
ATOM 1006 C CG  . GLN B 2 6   ? 276.144 350.465 485.955 1.00 125.09 ? 6   GLN L CG  1 
ATOM 1007 C CD  . GLN B 2 6   ? 277.107 351.570 486.307 1.00 125.09 ? 6   GLN L CD  1 
ATOM 1008 O OE1 . GLN B 2 6   ? 277.132 352.613 485.662 1.00 125.09 ? 6   GLN L OE1 1 
ATOM 1009 N NE2 . GLN B 2 6   ? 277.903 351.350 487.342 1.00 125.09 ? 6   GLN L NE2 1 
ATOM 1010 N N   . SER B 2 7   ? 275.331 346.910 488.668 1.00 134.61 ? 7   SER L N   1 
ATOM 1011 C CA  . SER B 2 7   ? 275.043 346.235 489.911 1.00 134.61 ? 7   SER L CA  1 
ATOM 1012 C C   . SER B 2 7   ? 276.368 345.915 490.584 1.00 134.61 ? 7   SER L C   1 
ATOM 1013 O O   . SER B 2 7   ? 277.288 345.435 489.906 1.00 134.61 ? 7   SER L O   1 
ATOM 1014 C CB  . SER B 2 7   ? 274.246 344.950 489.698 1.00 134.61 ? 7   SER L CB  1 
ATOM 1015 O OG  . SER B 2 7   ? 275.115 343.847 489.513 1.00 134.61 ? 7   SER L OG  1 
ATOM 1016 N N   . PRO B 2 8   ? 276.504 346.157 491.894 1.00 140.33 ? 8   PRO L N   1 
ATOM 1017 C CA  . PRO B 2 8   ? 275.514 346.759 492.791 1.00 140.33 ? 8   PRO L CA  1 
ATOM 1018 C C   . PRO B 2 8   ? 275.596 348.281 492.789 1.00 140.33 ? 8   PRO L C   1 
ATOM 1019 O O   . PRO B 2 8   ? 276.611 348.815 492.347 1.00 140.33 ? 8   PRO L O   1 
ATOM 1020 C CB  . PRO B 2 8   ? 275.905 346.190 494.150 1.00 140.33 ? 8   PRO L CB  1 
ATOM 1021 C CG  . PRO B 2 8   ? 277.354 346.052 494.057 1.00 140.33 ? 8   PRO L CG  1 
ATOM 1022 C CD  . PRO B 2 8   ? 277.681 345.685 492.640 1.00 140.33 ? 8   PRO L CD  1 
ATOM 1023 N N   . PRO B 2 9   ? 274.544 348.966 493.252 1.00 140.86 ? 9   PRO L N   1 
ATOM 1024 C CA  . PRO B 2 9   ? 274.634 350.433 493.342 1.00 140.86 ? 9   PRO L CA  1 
ATOM 1025 C C   . PRO B 2 9   ? 275.611 350.903 494.400 1.00 140.86 ? 9   PRO L C   1 
ATOM 1026 O O   . PRO B 2 9   ? 276.388 351.832 494.150 1.00 140.86 ? 9   PRO L O   1 
ATOM 1027 C CB  . PRO B 2 9   ? 273.195 350.854 493.670 1.00 140.86 ? 9   PRO L CB  1 
ATOM 1028 C CG  . PRO B 2 9   ? 272.354 349.702 493.260 1.00 140.86 ? 9   PRO L CG  1 
ATOM 1029 C CD  . PRO B 2 9   ? 273.175 348.489 493.511 1.00 140.86 ? 9   PRO L CD  1 
ATOM 1030 N N   . ILE B 2 10  ? 275.597 350.289 495.575 1.00 144.65 ? 10  ILE L N   1 
ATOM 1031 C CA  . ILE B 2 10  ? 276.549 350.605 496.629 1.00 144.65 ? 10  ILE L CA  1 
ATOM 1032 C C   . ILE B 2 10  ? 277.363 349.353 496.923 1.00 144.65 ? 10  ILE L C   1 
ATOM 1033 O O   . ILE B 2 10  ? 276.826 348.249 497.058 1.00 144.65 ? 10  ILE L O   1 
ATOM 1034 C CB  . ILE B 2 10  ? 275.844 351.154 497.894 1.00 144.65 ? 10  ILE L CB  1 
ATOM 1035 C CG1 . ILE B 2 10  ? 276.815 351.278 499.075 1.00 144.65 ? 10  ILE L CG1 1 
ATOM 1036 C CG2 . ILE B 2 10  ? 274.613 350.326 498.252 1.00 144.65 ? 10  ILE L CG2 1 
ATOM 1037 C CD1 . ILE B 2 10  ? 277.918 352.286 498.859 1.00 144.65 ? 10  ILE L CD1 1 
ATOM 1038 N N   . MET B 2 11  ? 278.679 349.527 496.978 1.00 147.82 ? 11  MET L N   1 
ATOM 1039 C CA  . MET B 2 11  ? 279.603 348.425 497.182 1.00 147.82 ? 11  MET L CA  1 
ATOM 1040 C C   . MET B 2 11  ? 280.784 348.916 498.001 1.00 147.82 ? 11  MET L C   1 
ATOM 1041 O O   . MET B 2 11  ? 281.377 349.955 497.710 1.00 147.82 ? 11  MET L O   1 
ATOM 1042 C CB  . MET B 2 11  ? 280.053 347.842 495.837 1.00 147.82 ? 11  MET L CB  1 
ATOM 1043 C CG  . MET B 2 11  ? 281.424 347.215 495.825 1.00 147.82 ? 11  MET L CG  1 
ATOM 1044 S SD  . MET B 2 11  ? 281.625 346.108 494.422 1.00 147.82 ? 11  MET L SD  1 
ATOM 1045 C CE  . MET B 2 11  ? 280.635 344.713 494.946 1.00 147.82 ? 11  MET L CE  1 
ATOM 1046 N N   . SER B 2 12  ? 281.111 348.160 499.046 1.00 152.93 ? 12  SER L N   1 
ATOM 1047 C CA  . SER B 2 12  ? 282.169 348.538 499.968 1.00 152.93 ? 12  SER L CA  1 
ATOM 1048 C C   . SER B 2 12  ? 283.266 347.486 499.964 1.00 152.93 ? 12  SER L C   1 
ATOM 1049 O O   . SER B 2 12  ? 282.997 346.297 499.765 1.00 152.93 ? 12  SER L O   1 
ATOM 1050 C CB  . SER B 2 12  ? 281.634 348.722 501.385 1.00 152.93 ? 12  SER L CB  1 
ATOM 1051 O OG  . SER B 2 12  ? 282.546 349.474 502.164 1.00 152.93 ? 12  SER L OG  1 
ATOM 1052 N N   . ALA B 2 13  ? 284.498 347.930 500.192 1.00 154.22 ? 13  ALA L N   1 
ATOM 1053 C CA  . ALA B 2 13  ? 285.649 347.043 500.149 1.00 154.22 ? 13  ALA L CA  1 
ATOM 1054 C C   . ALA B 2 13  ? 286.755 347.615 501.021 1.00 154.22 ? 13  ALA L C   1 
ATOM 1055 O O   . ALA B 2 13  ? 286.969 348.828 501.045 1.00 154.22 ? 13  ALA L O   1 
ATOM 1056 C CB  . ALA B 2 13  ? 286.153 346.855 498.715 1.00 154.22 ? 13  ALA L CB  1 
ATOM 1057 N N   . SER B 2 14  ? 287.448 346.734 501.731 1.00 154.89 ? 14  SER L N   1 
ATOM 1058 C CA  . SER B 2 14  ? 288.601 347.112 502.530 1.00 154.89 ? 14  SER L CA  1 
ATOM 1059 C C   . SER B 2 14  ? 289.838 347.217 501.639 1.00 154.89 ? 14  SER L C   1 
ATOM 1060 O O   . SER B 2 14  ? 289.861 346.655 500.543 1.00 154.89 ? 14  SER L O   1 
ATOM 1061 C CB  . SER B 2 14  ? 288.835 346.085 503.631 1.00 154.89 ? 14  SER L CB  1 
ATOM 1062 O OG  . SER B 2 14  ? 287.609 345.725 504.239 1.00 154.89 ? 14  SER L OG  1 
ATOM 1063 N N   . PRO B 2 15  ? 290.863 347.959 502.061 1.00 154.27 ? 15  PRO L N   1 
ATOM 1064 C CA  . PRO B 2 15  ? 292.109 347.987 501.282 1.00 154.27 ? 15  PRO L CA  1 
ATOM 1065 C C   . PRO B 2 15  ? 292.813 346.638 501.301 1.00 154.27 ? 15  PRO L C   1 
ATOM 1066 O O   . PRO B 2 15  ? 292.957 346.009 502.351 1.00 154.27 ? 15  PRO L O   1 
ATOM 1067 C CB  . PRO B 2 15  ? 292.941 349.066 501.983 1.00 154.27 ? 15  PRO L CB  1 
ATOM 1068 C CG  . PRO B 2 15  ? 291.935 349.952 502.602 1.00 154.27 ? 15  PRO L CG  1 
ATOM 1069 C CD  . PRO B 2 15  ? 290.824 349.051 503.049 1.00 154.27 ? 15  PRO L CD  1 
ATOM 1070 N N   . GLY B 2 16  ? 293.242 346.196 500.123 1.00 153.81 ? 16  GLY L N   1 
ATOM 1071 C CA  . GLY B 2 16  ? 293.980 344.961 499.968 1.00 153.81 ? 16  GLY L CA  1 
ATOM 1072 C C   . GLY B 2 16  ? 293.216 343.834 499.309 1.00 153.81 ? 16  GLY L C   1 
ATOM 1073 O O   . GLY B 2 16  ? 293.843 342.851 498.895 1.00 153.81 ? 16  GLY L O   1 
ATOM 1074 N N   . GLU B 2 17  ? 291.897 343.935 499.185 1.00 152.41 ? 17  GLU L N   1 
ATOM 1075 C CA  . GLU B 2 17  ? 291.119 342.845 498.617 1.00 152.41 ? 17  GLU L CA  1 
ATOM 1076 C C   . GLU B 2 17  ? 290.915 343.047 497.117 1.00 152.41 ? 17  GLU L C   1 
ATOM 1077 O O   . GLU B 2 17  ? 291.280 344.072 496.542 1.00 152.41 ? 17  GLU L O   1 
ATOM 1078 C CB  . GLU B 2 17  ? 289.773 342.725 499.328 1.00 152.41 ? 17  GLU L CB  1 
ATOM 1079 C CG  . GLU B 2 17  ? 288.861 343.908 499.118 1.00 152.41 ? 17  GLU L CG  1 
ATOM 1080 C CD  . GLU B 2 17  ? 287.636 343.859 500.007 1.00 152.41 ? 17  GLU L CD  1 
ATOM 1081 O OE1 . GLU B 2 17  ? 287.779 344.061 501.229 1.00 152.41 ? 17  GLU L OE1 1 
ATOM 1082 O OE2 . GLU B 2 17  ? 286.529 343.614 499.484 1.00 152.41 ? 17  GLU L OE2 1 
ATOM 1083 N N   . LYS B 2 18  ? 290.321 342.039 496.482 1.00 143.22 ? 18  LYS L N   1 
ATOM 1084 C CA  . LYS B 2 18  ? 290.011 342.065 495.058 1.00 143.22 ? 18  LYS L CA  1 
ATOM 1085 C C   . LYS B 2 18  ? 288.507 342.208 494.899 1.00 143.22 ? 18  LYS L C   1 
ATOM 1086 O O   . LYS B 2 18  ? 287.743 341.422 495.468 1.00 143.22 ? 18  LYS L O   1 
ATOM 1087 C CB  . LYS B 2 18  ? 290.503 340.800 494.356 1.00 143.22 ? 18  LYS L CB  1 
ATOM 1088 C CG  . LYS B 2 18  ? 290.236 340.802 492.865 1.00 143.22 ? 18  LYS L CG  1 
ATOM 1089 C CD  . LYS B 2 18  ? 290.804 339.575 492.192 1.00 143.22 ? 18  LYS L CD  1 
ATOM 1090 C CE  . LYS B 2 18  ? 289.980 338.356 492.541 1.00 143.22 ? 18  LYS L CE  1 
ATOM 1091 N NZ  . LYS B 2 18  ? 288.610 338.455 491.969 1.00 143.22 ? 18  LYS L NZ  1 
ATOM 1092 N N   . VAL B 2 19  ? 288.084 343.203 494.126 1.00 136.68 ? 19  VAL L N   1 
ATOM 1093 C CA  . VAL B 2 19  ? 286.679 343.569 494.041 1.00 136.68 ? 19  VAL L CA  1 
ATOM 1094 C C   . VAL B 2 19  ? 286.312 343.699 492.565 1.00 136.68 ? 19  VAL L C   1 
ATOM 1095 O O   . VAL B 2 19  ? 287.180 343.890 491.708 1.00 136.68 ? 19  VAL L O   1 
ATOM 1096 C CB  . VAL B 2 19  ? 286.422 344.880 494.826 1.00 136.68 ? 19  VAL L CB  1 
ATOM 1097 C CG1 . VAL B 2 19  ? 287.003 346.086 494.108 1.00 136.68 ? 19  VAL L CG1 1 
ATOM 1098 C CG2 . VAL B 2 19  ? 284.972 345.058 495.195 1.00 136.68 ? 19  VAL L CG2 1 
ATOM 1099 N N   . THR B 2 20  ? 285.022 343.559 492.262 1.00 132.81 ? 20  THR L N   1 
ATOM 1100 C CA  . THR B 2 20  ? 284.545 343.618 490.884 1.00 132.81 ? 20  THR L CA  1 
ATOM 1101 C C   . THR B 2 20  ? 283.129 344.172 490.847 1.00 132.81 ? 20  THR L C   1 
ATOM 1102 O O   . THR B 2 20  ? 282.374 344.034 491.813 1.00 132.81 ? 20  THR L O   1 
ATOM 1103 C CB  . THR B 2 20  ? 284.609 342.237 490.218 1.00 132.81 ? 20  THR L CB  1 
ATOM 1104 O OG1 . THR B 2 20  ? 284.190 342.339 488.854 1.00 132.81 ? 20  THR L OG1 1 
ATOM 1105 C CG2 . THR B 2 20  ? 283.742 341.222 490.942 1.00 132.81 ? 20  THR L CG2 1 
ATOM 1106 N N   . MET B 2 21  ? 282.794 344.844 489.751 1.00 127.04 ? 21  MET L N   1 
ATOM 1107 C CA  . MET B 2 21  ? 281.453 345.332 489.477 1.00 127.04 ? 21  MET L CA  1 
ATOM 1108 C C   . MET B 2 21  ? 281.056 344.951 488.059 1.00 127.04 ? 21  MET L C   1 
ATOM 1109 O O   . MET B 2 21  ? 281.904 344.649 487.219 1.00 127.04 ? 21  MET L O   1 
ATOM 1110 C CB  . MET B 2 21  ? 281.375 346.847 489.658 1.00 127.04 ? 21  MET L CB  1 
ATOM 1111 C CG  . MET B 2 21  ? 282.483 347.592 488.957 1.00 127.04 ? 21  MET L CG  1 
ATOM 1112 S SD  . MET B 2 21  ? 282.766 349.215 489.677 1.00 127.04 ? 21  MET L SD  1 
ATOM 1113 C CE  . MET B 2 21  ? 283.416 348.759 491.276 1.00 127.04 ? 21  MET L CE  1 
ATOM 1114 N N   . THR B 2 22  ? 279.754 344.975 487.792 1.00 126.33 ? 22  THR L N   1 
ATOM 1115 C CA  . THR B 2 22  ? 279.229 344.536 486.508 1.00 126.33 ? 22  THR L CA  1 
ATOM 1116 C C   . THR B 2 22  ? 278.397 345.639 485.873 1.00 126.33 ? 22  THR L C   1 
ATOM 1117 O O   . THR B 2 22  ? 277.943 346.572 486.537 1.00 126.33 ? 22  THR L O   1 
ATOM 1118 C CB  . THR B 2 22  ? 278.379 343.272 486.652 1.00 126.33 ? 22  THR L CB  1 
ATOM 1119 O OG1 . THR B 2 22  ? 277.409 343.468 487.687 1.00 126.33 ? 22  THR L OG1 1 
ATOM 1120 C CG2 . THR B 2 22  ? 279.248 342.081 486.992 1.00 126.33 ? 22  THR L CG2 1 
ATOM 1121 N N   . CYS B 2 23  ? 278.190 345.508 484.565 1.00 123.16 ? 23  CYS L N   1 
ATOM 1122 C CA  . CYS B 2 23  ? 277.403 346.474 483.805 1.00 123.16 ? 23  CYS L CA  1 
ATOM 1123 C C   . CYS B 2 23  ? 276.658 345.690 482.738 1.00 123.16 ? 23  CYS L C   1 
ATOM 1124 O O   . CYS B 2 23  ? 277.278 345.201 481.791 1.00 123.16 ? 23  CYS L O   1 
ATOM 1125 C CB  . CYS B 2 23  ? 278.301 347.544 483.191 1.00 123.16 ? 23  CYS L CB  1 
ATOM 1126 S SG  . CYS B 2 23  ? 277.546 348.611 481.932 1.00 123.16 ? 23  CYS L SG  1 
ATOM 1127 N N   . ARG B 2 24  ? 275.346 345.563 482.894 1.00 124.95 ? 24  ARG L N   1 
ATOM 1128 C CA  . ARG B 2 24  ? 274.533 344.702 482.048 1.00 124.95 ? 24  ARG L CA  1 
ATOM 1129 C C   . ARG B 2 24  ? 273.656 345.540 481.135 1.00 124.95 ? 24  ARG L C   1 
ATOM 1130 O O   . ARG B 2 24  ? 273.033 346.507 481.581 1.00 124.95 ? 24  ARG L O   1 
ATOM 1131 C CB  . ARG B 2 24  ? 273.665 343.776 482.893 1.00 124.95 ? 24  ARG L CB  1 
ATOM 1132 C CG  . ARG B 2 24  ? 273.081 342.612 482.123 1.00 124.95 ? 24  ARG L CG  1 
ATOM 1133 C CD  . ARG B 2 24  ? 272.762 341.451 483.046 1.00 124.95 ? 24  ARG L CD  1 
ATOM 1134 N NE  . ARG B 2 24  ? 273.969 340.767 483.500 1.00 124.95 ? 24  ARG L NE  1 
ATOM 1135 C CZ  . ARG B 2 24  ? 274.500 340.906 484.711 1.00 124.95 ? 24  ARG L CZ  1 
ATOM 1136 N NH1 . ARG B 2 24  ? 273.933 341.715 485.596 1.00 124.95 ? 24  ARG L NH1 1 
ATOM 1137 N NH2 . ARG B 2 24  ? 275.600 340.245 485.036 1.00 124.95 ? 24  ARG L NH2 1 
ATOM 1138 N N   . ALA B 2 25  ? 273.599 345.156 479.867 1.00 124.56 ? 25  ALA L N   1 
ATOM 1139 C CA  . ALA B 2 25  ? 272.808 345.854 478.868 1.00 124.56 ? 25  ALA L CA  1 
ATOM 1140 C C   . ALA B 2 25  ? 271.545 345.071 478.551 1.00 124.56 ? 25  ALA L C   1 
ATOM 1141 O O   . ALA B 2 25  ? 271.482 343.855 478.742 1.00 124.56 ? 25  ALA L O   1 
ATOM 1142 C CB  . ALA B 2 25  ? 273.611 346.066 477.587 1.00 124.56 ? 25  ALA L CB  1 
ATOM 1143 N N   . SER B 2 26  ? 270.536 345.782 478.054 1.00 123.68 ? 26  SER L N   1 
ATOM 1144 C CA  . SER B 2 26  ? 269.296 345.126 477.665 1.00 123.68 ? 26  SER L CA  1 
ATOM 1145 C C   . SER B 2 26  ? 269.430 344.414 476.329 1.00 123.68 ? 26  SER L C   1 
ATOM 1146 O O   . SER B 2 26  ? 268.876 343.324 476.156 1.00 123.68 ? 26  SER L O   1 
ATOM 1147 C CB  . SER B 2 26  ? 268.159 346.143 477.596 1.00 123.68 ? 26  SER L CB  1 
ATOM 1148 O OG  . SER B 2 26  ? 268.079 346.710 476.302 1.00 123.68 ? 26  SER L OG  1 
ATOM 1149 N N   . SER B 2 27  ? 270.152 345.005 475.384 1.00 122.43 ? 27  SER L N   1 
ATOM 1150 C CA  . SER B 2 27  ? 270.381 344.405 474.081 1.00 122.43 ? 27  SER L CA  1 
ATOM 1151 C C   . SER B 2 27  ? 271.872 344.185 473.887 1.00 122.43 ? 27  SER L C   1 
ATOM 1152 O O   . SER B 2 27  ? 272.688 344.547 474.735 1.00 122.43 ? 27  SER L O   1 
ATOM 1153 C CB  . SER B 2 27  ? 269.829 345.280 472.956 1.00 122.43 ? 27  SER L CB  1 
ATOM 1154 O OG  . SER B 2 27  ? 270.165 346.636 473.174 1.00 122.43 ? 27  SER L OG  1 
ATOM 1155 N N   . SER B 2 28  ? 272.224 343.582 472.757 1.00 118.22 ? 28  SER L N   1 
ATOM 1156 C CA  . SER B 2 28  ? 273.621 343.286 472.482 1.00 118.22 ? 28  SER L CA  1 
ATOM 1157 C C   . SER B 2 28  ? 274.358 344.547 472.053 1.00 118.22 ? 28  SER L C   1 
ATOM 1158 O O   . SER B 2 28  ? 273.998 345.182 471.059 1.00 118.22 ? 28  SER L O   1 
ATOM 1159 C CB  . SER B 2 28  ? 273.733 342.217 471.402 1.00 118.22 ? 28  SER L CB  1 
ATOM 1160 O OG  . SER B 2 28  ? 275.085 342.018 471.034 1.00 118.22 ? 28  SER L OG  1 
ATOM 1161 N N   . VAL B 2 29  ? 275.387 344.904 472.804 1.00 108.68 ? 29  VAL L N   1 
ATOM 1162 C CA  . VAL B 2 29  ? 276.226 346.042 472.491 1.00 108.68 ? 29  VAL L CA  1 
ATOM 1163 C C   . VAL B 2 29  ? 277.593 345.521 472.062 1.00 108.68 ? 29  VAL L C   1 
ATOM 1164 O O   . VAL B 2 29  ? 278.119 344.551 472.613 1.00 108.68 ? 29  VAL L O   1 
ATOM 1165 C CB  . VAL B 2 29  ? 276.303 347.013 473.698 1.00 108.68 ? 29  VAL L CB  1 
ATOM 1166 C CG1 . VAL B 2 29  ? 276.667 346.276 474.962 1.00 108.68 ? 29  VAL L CG1 1 
ATOM 1167 C CG2 . VAL B 2 29  ? 277.265 348.157 473.454 1.00 108.68 ? 29  VAL L CG2 1 
ATOM 1168 N N   . SER B 2 30  ? 278.148 346.135 471.018 1.00 106.13 ? 30  SER L N   1 
ATOM 1169 C CA  . SER B 2 30  ? 279.426 345.707 470.469 1.00 106.13 ? 30  SER L CA  1 
ATOM 1170 C C   . SER B 2 30  ? 280.555 345.959 471.456 1.00 106.13 ? 30  SER L C   1 
ATOM 1171 O O   . SER B 2 30  ? 280.486 346.856 472.297 1.00 106.13 ? 30  SER L O   1 
ATOM 1172 C CB  . SER B 2 30  ? 279.713 346.437 469.163 1.00 106.13 ? 30  SER L CB  1 
ATOM 1173 O OG  . SER B 2 30  ? 280.780 345.819 468.472 1.00 106.13 ? 30  SER L OG  1 
ATOM 1174 N N   . SER B 2 31  ? 281.607 345.150 471.344 1.00 104.89 ? 31  SER L N   1 
ATOM 1175 C CA  . SER B 2 31  ? 282.646 345.147 472.362 1.00 104.89 ? 31  SER L CA  1 
ATOM 1176 C C   . SER B 2 31  ? 283.578 346.339 472.262 1.00 104.89 ? 31  SER L C   1 
ATOM 1177 O O   . SER B 2 31  ? 284.282 346.635 473.228 1.00 104.89 ? 31  SER L O   1 
ATOM 1178 C CB  . SER B 2 31  ? 283.471 343.872 472.276 1.00 104.89 ? 31  SER L CB  1 
ATOM 1179 O OG  . SER B 2 31  ? 284.747 344.081 472.849 1.00 104.89 ? 31  SER L OG  1 
ATOM 1180 N N   . SER B 2 32  ? 283.619 347.020 471.129 1.00 101.57 ? 32  SER L N   1 
ATOM 1181 C CA  . SER B 2 32  ? 284.512 348.155 470.989 1.00 101.57 ? 32  SER L CA  1 
ATOM 1182 C C   . SER B 2 32  ? 283.846 349.472 471.331 1.00 101.57 ? 32  SER L C   1 
ATOM 1183 O O   . SER B 2 32  ? 284.491 350.515 471.227 1.00 101.57 ? 32  SER L O   1 
ATOM 1184 C CB  . SER B 2 32  ? 285.052 348.229 469.571 1.00 101.57 ? 32  SER L CB  1 
ATOM 1185 O OG  . SER B 2 32  ? 284.215 349.047 468.783 1.00 101.57 ? 32  SER L OG  1 
ATOM 1186 N N   . TYR B 2 33  ? 282.577 349.458 471.725 1.00 101.76 ? 33  TYR L N   1 
ATOM 1187 C CA  . TYR B 2 33  ? 281.842 350.685 471.987 1.00 101.76 ? 33  TYR L CA  1 
ATOM 1188 C C   . TYR B 2 33  ? 281.395 350.810 473.432 1.00 101.76 ? 33  TYR L C   1 
ATOM 1189 O O   . TYR B 2 33  ? 280.405 351.496 473.697 1.00 101.76 ? 33  TYR L O   1 
ATOM 1190 C CB  . TYR B 2 33  ? 280.616 350.783 471.078 1.00 101.76 ? 33  TYR L CB  1 
ATOM 1191 C CG  . TYR B 2 33  ? 280.929 351.044 469.632 1.00 101.76 ? 33  TYR L CG  1 
ATOM 1192 C CD1 . TYR B 2 33  ? 282.133 351.603 469.254 1.00 101.76 ? 33  TYR L CD1 1 
ATOM 1193 C CD2 . TYR B 2 33  ? 280.011 350.733 468.643 1.00 101.76 ? 33  TYR L CD2 1 
ATOM 1194 C CE1 . TYR B 2 33  ? 282.418 351.840 467.935 1.00 101.76 ? 33  TYR L CE1 1 
ATOM 1195 C CE2 . TYR B 2 33  ? 280.289 350.968 467.323 1.00 101.76 ? 33  TYR L CE2 1 
ATOM 1196 C CZ  . TYR B 2 33  ? 281.493 351.522 466.978 1.00 101.76 ? 33  TYR L CZ  1 
ATOM 1197 O OH  . TYR B 2 33  ? 281.781 351.761 465.660 1.00 101.76 ? 33  TYR L OH  1 
ATOM 1198 N N   . LEU B 2 34  ? 282.072 350.159 474.369 1.00 103.71 ? 34  LEU L N   1 
ATOM 1199 C CA  . LEU B 2 34  ? 281.692 350.220 475.773 1.00 103.71 ? 34  LEU L CA  1 
ATOM 1200 C C   . LEU B 2 34  ? 282.860 350.707 476.614 1.00 103.71 ? 34  LEU L C   1 
ATOM 1201 O O   . LEU B 2 34  ? 283.897 350.044 476.682 1.00 103.71 ? 34  LEU L O   1 
ATOM 1202 C CB  . LEU B 2 34  ? 281.215 348.857 476.256 1.00 103.71 ? 34  LEU L CB  1 
ATOM 1203 C CG  . LEU B 2 34  ? 280.709 348.828 477.687 1.00 103.71 ? 34  LEU L CG  1 
ATOM 1204 C CD1 . LEU B 2 34  ? 279.357 348.188 477.713 1.00 103.71 ? 34  LEU L CD1 1 
ATOM 1205 C CD2 . LEU B 2 34  ? 281.659 348.030 478.537 1.00 103.71 ? 34  LEU L CD2 1 
ATOM 1206 N N   . HIS B 2 35  ? 282.676 351.843 477.279 1.00 104.82 ? 35  HIS L N   1 
ATOM 1207 C CA  . HIS B 2 35  ? 283.744 352.486 478.024 1.00 104.82 ? 35  HIS L CA  1 
ATOM 1208 C C   . HIS B 2 35  ? 283.357 352.651 479.484 1.00 104.82 ? 35  HIS L C   1 
ATOM 1209 O O   . HIS B 2 35  ? 282.190 352.534 479.854 1.00 104.82 ? 35  HIS L O   1 
ATOM 1210 C CB  . HIS B 2 35  ? 284.088 353.850 477.439 1.00 104.82 ? 35  HIS L CB  1 
ATOM 1211 C CG  . HIS B 2 35  ? 283.972 353.915 475.953 1.00 104.82 ? 35  HIS L CG  1 
ATOM 1212 N ND1 . HIS B 2 35  ? 284.795 353.200 475.114 1.00 104.82 ? 35  HIS L ND1 1 
ATOM 1213 C CD2 . HIS B 2 35  ? 283.142 354.622 475.155 1.00 104.82 ? 35  HIS L CD2 1 
ATOM 1214 C CE1 . HIS B 2 35  ? 284.470 353.457 473.861 1.00 104.82 ? 35  HIS L CE1 1 
ATOM 1215 N NE2 . HIS B 2 35  ? 283.471 354.318 473.858 1.00 104.82 ? 35  HIS L NE2 1 
ATOM 1216 N N   . TRP B 2 36  ? 284.357 352.944 480.312 1.00 108.81 ? 36  TRP L N   1 
ATOM 1217 C CA  . TRP B 2 36  ? 284.175 353.126 481.744 1.00 108.81 ? 36  TRP L CA  1 
ATOM 1218 C C   . TRP B 2 36  ? 284.752 354.465 482.172 1.00 108.81 ? 36  TRP L C   1 
ATOM 1219 O O   . TRP B 2 36  ? 285.831 354.852 481.721 1.00 108.81 ? 36  TRP L O   1 
ATOM 1220 C CB  . TRP B 2 36  ? 284.858 352.019 482.531 1.00 108.81 ? 36  TRP L CB  1 
ATOM 1221 C CG  . TRP B 2 36  ? 284.242 350.688 482.363 1.00 108.81 ? 36  TRP L CG  1 
ATOM 1222 C CD1 . TRP B 2 36  ? 284.457 349.814 481.350 1.00 108.81 ? 36  TRP L CD1 1 
ATOM 1223 C CD2 . TRP B 2 36  ? 283.315 350.063 483.245 1.00 108.81 ? 36  TRP L CD2 1 
ATOM 1224 N NE1 . TRP B 2 36  ? 283.716 348.678 481.540 1.00 108.81 ? 36  TRP L NE1 1 
ATOM 1225 C CE2 . TRP B 2 36  ? 283.003 348.810 482.700 1.00 108.81 ? 36  TRP L CE2 1 
ATOM 1226 C CE3 . TRP B 2 36  ? 282.712 350.445 484.443 1.00 108.81 ? 36  TRP L CE3 1 
ATOM 1227 C CZ2 . TRP B 2 36  ? 282.118 347.938 483.308 1.00 108.81 ? 36  TRP L CZ2 1 
ATOM 1228 C CZ3 . TRP B 2 36  ? 281.834 349.578 485.044 1.00 108.81 ? 36  TRP L CZ3 1 
ATOM 1229 C CH2 . TRP B 2 36  ? 281.545 348.340 484.479 1.00 108.81 ? 36  TRP L CH2 1 
ATOM 1230 N N   . TYR B 2 37  ? 284.047 355.156 483.061 1.00 108.30 ? 37  TYR L N   1 
ATOM 1231 C CA  . TYR B 2 37  ? 284.491 356.439 483.579 1.00 108.30 ? 37  TYR L CA  1 
ATOM 1232 C C   . TYR B 2 37  ? 284.620 356.361 485.090 1.00 108.30 ? 37  TYR L C   1 
ATOM 1233 O O   . TYR B 2 37  ? 284.123 355.431 485.725 1.00 108.30 ? 37  TYR L O   1 
ATOM 1234 C CB  . TYR B 2 37  ? 283.524 357.559 483.214 1.00 108.30 ? 37  TYR L CB  1 
ATOM 1235 C CG  . TYR B 2 37  ? 283.405 357.804 481.739 1.00 108.30 ? 37  TYR L CG  1 
ATOM 1236 C CD1 . TYR B 2 37  ? 284.278 358.653 481.090 1.00 108.30 ? 37  TYR L CD1 1 
ATOM 1237 C CD2 . TYR B 2 37  ? 282.415 357.190 480.998 1.00 108.30 ? 37  TYR L CD2 1 
ATOM 1238 C CE1 . TYR B 2 37  ? 284.170 358.882 479.742 1.00 108.30 ? 37  TYR L CE1 1 
ATOM 1239 C CE2 . TYR B 2 37  ? 282.300 357.414 479.651 1.00 108.30 ? 37  TYR L CE2 1 
ATOM 1240 C CZ  . TYR B 2 37  ? 283.180 358.259 479.030 1.00 108.30 ? 37  TYR L CZ  1 
ATOM 1241 O OH  . TYR B 2 37  ? 283.071 358.484 477.684 1.00 108.30 ? 37  TYR L OH  1 
ATOM 1242 N N   . GLN B 2 38  ? 285.290 357.353 485.666 1.00 114.15 ? 38  GLN L N   1 
ATOM 1243 C CA  . GLN B 2 38  ? 285.430 357.461 487.112 1.00 114.15 ? 38  GLN L CA  1 
ATOM 1244 C C   . GLN B 2 38  ? 285.291 358.916 487.515 1.00 114.15 ? 38  GLN L C   1 
ATOM 1245 O O   . GLN B 2 38  ? 286.101 359.753 487.110 1.00 114.15 ? 38  GLN L O   1 
ATOM 1246 C CB  . GLN B 2 38  ? 286.773 356.923 487.593 1.00 114.15 ? 38  GLN L CB  1 
ATOM 1247 C CG  . GLN B 2 38  ? 287.020 357.226 489.054 1.00 114.15 ? 38  GLN L CG  1 
ATOM 1248 C CD  . GLN B 2 38  ? 288.469 357.086 489.447 1.00 114.15 ? 38  GLN L CD  1 
ATOM 1249 O OE1 . GLN B 2 38  ? 289.248 358.027 489.323 1.00 114.15 ? 38  GLN L OE1 1 
ATOM 1250 N NE2 . GLN B 2 38  ? 288.836 355.912 489.939 1.00 114.15 ? 38  GLN L NE2 1 
ATOM 1251 N N   . GLN B 2 39  ? 284.280 359.213 488.321 1.00 122.12 ? 39  GLN L N   1 
ATOM 1252 C CA  . GLN B 2 39  ? 284.038 360.562 488.808 1.00 122.12 ? 39  GLN L CA  1 
ATOM 1253 C C   . GLN B 2 39  ? 284.234 360.575 490.311 1.00 122.12 ? 39  GLN L C   1 
ATOM 1254 O O   . GLN B 2 39  ? 283.524 359.873 491.038 1.00 122.12 ? 39  GLN L O   1 
ATOM 1255 C CB  . GLN B 2 39  ? 282.630 361.037 488.455 1.00 122.12 ? 39  GLN L CB  1 
ATOM 1256 C CG  . GLN B 2 39  ? 282.320 362.428 488.959 1.00 122.12 ? 39  GLN L CG  1 
ATOM 1257 C CD  . GLN B 2 39  ? 280.854 362.768 488.858 1.00 122.12 ? 39  GLN L CD  1 
ATOM 1258 O OE1 . GLN B 2 39  ? 280.011 361.887 488.725 1.00 122.12 ? 39  GLN L OE1 1 
ATOM 1259 N NE2 . GLN B 2 39  ? 280.540 364.053 488.918 1.00 122.12 ? 39  GLN L NE2 1 
ATOM 1260 N N   . LYS B 2 40  ? 285.188 361.375 490.776 1.00 130.13 ? 40  LYS L N   1 
ATOM 1261 C CA  . LYS B 2 40  ? 285.398 361.537 492.204 1.00 130.13 ? 40  LYS L CA  1 
ATOM 1262 C C   . LYS B 2 40  ? 284.362 362.500 492.773 1.00 130.13 ? 40  LYS L C   1 
ATOM 1263 O O   . LYS B 2 40  ? 283.503 363.025 492.062 1.00 130.13 ? 40  LYS L O   1 
ATOM 1264 C CB  . LYS B 2 40  ? 286.815 362.019 492.480 1.00 130.13 ? 40  LYS L CB  1 
ATOM 1265 C CG  . LYS B 2 40  ? 287.846 360.919 492.413 1.00 130.13 ? 40  LYS L CG  1 
ATOM 1266 C CD  . LYS B 2 40  ? 289.186 361.397 492.921 1.00 130.13 ? 40  LYS L CD  1 
ATOM 1267 C CE  . LYS B 2 40  ? 290.175 360.256 493.004 1.00 130.13 ? 40  LYS L CE  1 
ATOM 1268 N NZ  . LYS B 2 40  ? 291.474 360.708 493.567 1.00 130.13 ? 40  LYS L NZ  1 
ATOM 1269 N N   . SER B 2 41  ? 284.449 362.742 494.077 1.00 132.13 ? 41  SER L N   1 
ATOM 1270 C CA  . SER B 2 41  ? 283.440 363.524 494.781 1.00 132.13 ? 41  SER L CA  1 
ATOM 1271 C C   . SER B 2 41  ? 283.596 364.997 494.424 1.00 132.13 ? 41  SER L C   1 
ATOM 1272 O O   . SER B 2 41  ? 284.579 365.637 494.809 1.00 132.13 ? 41  SER L O   1 
ATOM 1273 C CB  . SER B 2 41  ? 283.557 363.305 496.285 1.00 132.13 ? 41  SER L CB  1 
ATOM 1274 O OG  . SER B 2 41  ? 283.230 361.970 496.625 1.00 132.13 ? 41  SER L OG  1 
ATOM 1275 N N   . GLY B 2 42  ? 282.630 365.530 493.683 1.00 133.98 ? 42  GLY L N   1 
ATOM 1276 C CA  . GLY B 2 42  ? 282.631 366.941 493.352 1.00 133.98 ? 42  GLY L CA  1 
ATOM 1277 C C   . GLY B 2 42  ? 283.659 367.351 492.327 1.00 133.98 ? 42  GLY L C   1 
ATOM 1278 O O   . GLY B 2 42  ? 284.176 368.469 492.392 1.00 133.98 ? 42  GLY L O   1 
ATOM 1279 N N   . ALA B 2 43  ? 283.977 366.477 491.379 1.00 131.51 ? 43  ALA L N   1 
ATOM 1280 C CA  . ALA B 2 43  ? 284.943 366.781 490.336 1.00 131.51 ? 43  ALA L CA  1 
ATOM 1281 C C   . ALA B 2 43  ? 284.374 366.376 488.986 1.00 131.51 ? 43  ALA L C   1 
ATOM 1282 O O   . ALA B 2 43  ? 283.354 365.690 488.894 1.00 131.51 ? 43  ALA L O   1 
ATOM 1283 C CB  . ALA B 2 43  ? 286.280 366.073 490.584 1.00 131.51 ? 43  ALA L CB  1 
ATOM 1284 N N   . SER B 2 44  ? 285.049 366.815 487.932 1.00 125.45 ? 44  SER L N   1 
ATOM 1285 C CA  . SER B 2 44  ? 284.670 366.411 486.593 1.00 125.45 ? 44  SER L CA  1 
ATOM 1286 C C   . SER B 2 44  ? 285.056 364.952 486.366 1.00 125.45 ? 44  SER L C   1 
ATOM 1287 O O   . SER B 2 44  ? 286.062 364.483 486.901 1.00 125.45 ? 44  SER L O   1 
ATOM 1288 C CB  . SER B 2 44  ? 285.355 367.295 485.564 1.00 125.45 ? 44  SER L CB  1 
ATOM 1289 O OG  . SER B 2 44  ? 286.712 367.498 485.910 1.00 125.45 ? 44  SER L OG  1 
ATOM 1290 N N   . PRO B 2 45  ? 284.263 364.209 485.597 1.00 117.30 ? 45  PRO L N   1 
ATOM 1291 C CA  . PRO B 2 45  ? 284.586 362.798 485.349 1.00 117.30 ? 45  PRO L CA  1 
ATOM 1292 C C   . PRO B 2 45  ? 285.821 362.620 484.490 1.00 117.30 ? 45  PRO L C   1 
ATOM 1293 O O   . PRO B 2 45  ? 286.269 363.561 483.833 1.00 117.30 ? 45  PRO L O   1 
ATOM 1294 C CB  . PRO B 2 45  ? 283.333 362.275 484.639 1.00 117.30 ? 45  PRO L CB  1 
ATOM 1295 C CG  . PRO B 2 45  ? 282.263 363.212 485.026 1.00 117.30 ? 45  PRO L CG  1 
ATOM 1296 C CD  . PRO B 2 45  ? 282.917 364.545 485.117 1.00 117.30 ? 45  PRO L CD  1 
ATOM 1297 N N   . LYS B 2 46  ? 286.392 361.420 484.501 1.00 115.40 ? 46  LYS L N   1 
ATOM 1298 C CA  . LYS B 2 46  ? 287.594 361.138 483.737 1.00 115.40 ? 46  LYS L CA  1 
ATOM 1299 C C   . LYS B 2 46  ? 287.438 359.793 483.054 1.00 115.40 ? 46  LYS L C   1 
ATOM 1300 O O   . LYS B 2 46  ? 286.818 358.877 483.597 1.00 115.40 ? 46  LYS L O   1 
ATOM 1301 C CB  . LYS B 2 46  ? 288.838 361.129 484.625 1.00 115.40 ? 46  LYS L CB  1 
ATOM 1302 C CG  . LYS B 2 46  ? 289.280 362.500 485.098 1.00 115.40 ? 46  LYS L CG  1 
ATOM 1303 C CD  . LYS B 2 46  ? 290.290 362.401 486.233 1.00 115.40 ? 46  LYS L CD  1 
ATOM 1304 C CE  . LYS B 2 46  ? 291.472 361.518 485.863 1.00 115.40 ? 46  LYS L CE  1 
ATOM 1305 N NZ  . LYS B 2 46  ? 292.143 361.966 484.611 1.00 115.40 ? 46  LYS L NZ  1 
ATOM 1306 N N   . LEU B 2 47  ? 287.996 359.685 481.855 1.00 108.71 ? 47  LEU L N   1 
ATOM 1307 C CA  . LEU B 2 47  ? 287.957 358.425 481.131 1.00 108.71 ? 47  LEU L CA  1 
ATOM 1308 C C   . LEU B 2 47  ? 288.895 357.423 481.783 1.00 108.71 ? 47  LEU L C   1 
ATOM 1309 O O   . LEU B 2 47  ? 290.041 357.739 482.099 1.00 108.71 ? 47  LEU L O   1 
ATOM 1310 C CB  . LEU B 2 47  ? 288.345 358.639 479.675 1.00 108.71 ? 47  LEU L CB  1 
ATOM 1311 C CG  . LEU B 2 47  ? 288.346 357.388 478.808 1.00 108.71 ? 47  LEU L CG  1 
ATOM 1312 C CD1 . LEU B 2 47  ? 286.980 357.151 478.238 1.00 108.71 ? 47  LEU L CD1 1 
ATOM 1313 C CD2 . LEU B 2 47  ? 289.354 357.536 477.707 1.00 108.71 ? 47  LEU L CD2 1 
ATOM 1314 N N   . TRP B 2 48  ? 288.403 356.210 481.992 1.00 112.95 ? 48  TRP L N   1 
ATOM 1315 C CA  . TRP B 2 48  ? 289.167 355.200 482.706 1.00 112.95 ? 48  TRP L CA  1 
ATOM 1316 C C   . TRP B 2 48  ? 289.557 354.029 481.823 1.00 112.95 ? 48  TRP L C   1 
ATOM 1317 O O   . TRP B 2 48  ? 290.744 353.711 481.717 1.00 112.95 ? 48  TRP L O   1 
ATOM 1318 C CB  . TRP B 2 48  ? 288.361 354.709 483.914 1.00 112.95 ? 48  TRP L CB  1 
ATOM 1319 C CG  . TRP B 2 48  ? 289.175 354.412 485.130 1.00 112.95 ? 48  TRP L CG  1 
ATOM 1320 C CD1 . TRP B 2 48  ? 289.302 353.208 485.743 1.00 112.95 ? 48  TRP L CD1 1 
ATOM 1321 C CD2 . TRP B 2 48  ? 289.961 355.335 485.889 1.00 112.95 ? 48  TRP L CD2 1 
ATOM 1322 N NE1 . TRP B 2 48  ? 290.120 353.318 486.836 1.00 112.95 ? 48  TRP L NE1 1 
ATOM 1323 C CE2 . TRP B 2 48  ? 290.534 354.617 486.949 1.00 112.95 ? 48  TRP L CE2 1 
ATOM 1324 C CE3 . TRP B 2 48  ? 290.234 356.700 485.778 1.00 112.95 ? 48  TRP L CE3 1 
ATOM 1325 C CZ2 . TRP B 2 48  ? 291.369 355.212 487.883 1.00 112.95 ? 48  TRP L CZ2 1 
ATOM 1326 C CZ3 . TRP B 2 48  ? 291.058 357.287 486.706 1.00 112.95 ? 48  TRP L CZ3 1 
ATOM 1327 C CH2 . TRP B 2 48  ? 291.618 356.545 487.745 1.00 112.95 ? 48  TRP L CH2 1 
ATOM 1328 N N   . ILE B 2 49  ? 288.595 353.374 481.188 1.00 107.62 ? 49  ILE L N   1 
ATOM 1329 C CA  . ILE B 2 49  ? 288.869 352.257 480.295 1.00 107.62 ? 49  ILE L CA  1 
ATOM 1330 C C   . ILE B 2 49  ? 288.034 352.453 479.044 1.00 107.62 ? 49  ILE L C   1 
ATOM 1331 O O   . ILE B 2 49  ? 286.814 352.613 479.132 1.00 107.62 ? 49  ILE L O   1 
ATOM 1332 C CB  . ILE B 2 49  ? 288.548 350.903 480.952 1.00 107.62 ? 49  ILE L CB  1 
ATOM 1333 C CG1 . ILE B 2 49  ? 289.609 350.553 481.985 1.00 107.62 ? 49  ILE L CG1 1 
ATOM 1334 C CG2 . ILE B 2 49  ? 288.470 349.802 479.915 1.00 107.62 ? 49  ILE L CG2 1 
ATOM 1335 C CD1 . ILE B 2 49  ? 289.393 349.229 482.639 1.00 107.62 ? 49  ILE L CD1 1 
ATOM 1336 N N   . TYR B 2 50  ? 288.679 352.461 477.886 1.00 106.43 ? 50  TYR L N   1 
ATOM 1337 C CA  . TYR B 2 50  ? 287.996 352.592 476.611 1.00 106.43 ? 50  TYR L CA  1 
ATOM 1338 C C   . TYR B 2 50  ? 288.088 351.280 475.850 1.00 106.43 ? 50  TYR L C   1 
ATOM 1339 O O   . TYR B 2 50  ? 289.078 350.554 475.980 1.00 106.43 ? 50  TYR L O   1 
ATOM 1340 C CB  . TYR B 2 50  ? 288.594 353.729 475.785 1.00 106.43 ? 50  TYR L CB  1 
ATOM 1341 C CG  . TYR B 2 50  ? 289.929 353.426 475.153 1.00 106.43 ? 50  TYR L CG  1 
ATOM 1342 C CD1 . TYR B 2 50  ? 291.087 353.408 475.907 1.00 106.43 ? 50  TYR L CD1 1 
ATOM 1343 C CD2 . TYR B 2 50  ? 290.033 353.182 473.796 1.00 106.43 ? 50  TYR L CD2 1 
ATOM 1344 C CE1 . TYR B 2 50  ? 292.303 353.141 475.330 1.00 106.43 ? 50  TYR L CE1 1 
ATOM 1345 C CE2 . TYR B 2 50  ? 291.244 352.914 473.213 1.00 106.43 ? 50  TYR L CE2 1 
ATOM 1346 C CZ  . TYR B 2 50  ? 292.373 352.895 473.984 1.00 106.43 ? 50  TYR L CZ  1 
ATOM 1347 O OH  . TYR B 2 50  ? 293.584 352.627 473.401 1.00 106.43 ? 50  TYR L OH  1 
ATOM 1348 N N   . SER B 2 51  ? 287.037 350.983 475.075 1.00 106.71 ? 51  SER L N   1 
ATOM 1349 C CA  . SER B 2 51  ? 286.925 349.773 474.250 1.00 106.71 ? 51  SER L CA  1 
ATOM 1350 C C   . SER B 2 51  ? 287.054 348.495 475.076 1.00 106.71 ? 51  SER L C   1 
ATOM 1351 O O   . SER B 2 51  ? 287.717 347.544 474.669 1.00 106.71 ? 51  SER L O   1 
ATOM 1352 C CB  . SER B 2 51  ? 287.934 349.785 473.103 1.00 106.71 ? 51  SER L CB  1 
ATOM 1353 O OG  . SER B 2 51  ? 288.154 348.474 472.623 1.00 106.71 ? 51  SER L OG  1 
ATOM 1354 N N   . THR B 2 52  ? 286.521 348.545 476.300 1.00 111.01 ? 52  THR L N   1 
ATOM 1355 C CA  . THR B 2 52  ? 286.195 347.495 477.273 1.00 111.01 ? 52  THR L CA  1 
ATOM 1356 C C   . THR B 2 52  ? 287.382 346.708 477.819 1.00 111.01 ? 52  THR L C   1 
ATOM 1357 O O   . THR B 2 52  ? 287.220 345.950 478.779 1.00 111.01 ? 52  THR L O   1 
ATOM 1358 C CB  . THR B 2 52  ? 285.162 346.483 476.747 1.00 111.01 ? 52  THR L CB  1 
ATOM 1359 O OG1 . THR B 2 52  ? 284.625 345.794 477.875 1.00 111.01 ? 52  THR L OG1 1 
ATOM 1360 C CG2 . THR B 2 52  ? 285.774 345.379 475.891 1.00 111.01 ? 52  THR L CG2 1 
ATOM 1361 N N   . SER B 2 53  ? 288.564 346.892 477.271 1.00 109.81 ? 53  SER L N   1 
ATOM 1362 C CA  . SER B 2 53  ? 289.713 346.175 477.803 1.00 109.81 ? 53  SER L CA  1 
ATOM 1363 C C   . SER B 2 53  ? 291.005 346.971 477.771 1.00 109.81 ? 53  SER L C   1 
ATOM 1364 O O   . SER B 2 53  ? 292.035 346.438 478.184 1.00 109.81 ? 53  SER L O   1 
ATOM 1365 C CB  . SER B 2 53  ? 289.903 344.862 477.037 1.00 109.81 ? 53  SER L CB  1 
ATOM 1366 O OG  . SER B 2 53  ? 291.233 344.401 477.160 1.00 109.81 ? 53  SER L OG  1 
ATOM 1367 N N   . ASN B 2 54  ? 290.997 348.211 477.311 1.00 109.79 ? 54  ASN L N   1 
ATOM 1368 C CA  . ASN B 2 54  ? 292.221 348.971 477.132 1.00 109.79 ? 54  ASN L CA  1 
ATOM 1369 C C   . ASN B 2 54  ? 292.278 350.093 478.151 1.00 109.79 ? 54  ASN L C   1 
ATOM 1370 O O   . ASN B 2 54  ? 291.286 350.790 478.372 1.00 109.79 ? 54  ASN L O   1 
ATOM 1371 C CB  . ASN B 2 54  ? 292.307 349.536 475.719 1.00 109.79 ? 54  ASN L CB  1 
ATOM 1372 C CG  . ASN B 2 54  ? 292.357 348.456 474.675 1.00 109.79 ? 54  ASN L CG  1 
ATOM 1373 O OD1 . ASN B 2 54  ? 293.427 347.980 474.312 1.00 109.79 ? 54  ASN L OD1 1 
ATOM 1374 N ND2 . ASN B 2 54  ? 291.194 348.053 474.188 1.00 109.79 ? 54  ASN L ND2 1 
ATOM 1375 N N   . LEU B 2 55  ? 293.437 350.260 478.766 1.00 114.99 ? 55  LEU L N   1 
ATOM 1376 C CA  . LEU B 2 55  ? 293.615 351.283 479.776 1.00 114.99 ? 55  LEU L CA  1 
ATOM 1377 C C   . LEU B 2 55  ? 293.759 352.650 479.127 1.00 114.99 ? 55  LEU L C   1 
ATOM 1378 O O   . LEU B 2 55  ? 294.202 352.774 477.984 1.00 114.99 ? 55  LEU L O   1 
ATOM 1379 C CB  . LEU B 2 55  ? 294.845 350.970 480.619 1.00 114.99 ? 55  LEU L CB  1 
ATOM 1380 C CG  . LEU B 2 55  ? 294.713 349.759 481.536 1.00 114.99 ? 55  LEU L CG  1 
ATOM 1381 C CD1 . LEU B 2 55  ? 296.042 349.461 482.191 1.00 114.99 ? 55  LEU L CD1 1 
ATOM 1382 C CD2 . LEU B 2 55  ? 293.649 350.014 482.576 1.00 114.99 ? 55  LEU L CD2 1 
ATOM 1383 N N   . ALA B 2 56  ? 293.387 353.684 479.872 1.00 118.33 ? 56  ALA L N   1 
ATOM 1384 C CA  . ALA B 2 56  ? 293.552 355.052 479.404 1.00 118.33 ? 56  ALA L CA  1 
ATOM 1385 C C   . ALA B 2 56  ? 294.983 355.506 479.676 1.00 118.33 ? 56  ALA L C   1 
ATOM 1386 O O   . ALA B 2 56  ? 295.851 354.720 480.061 1.00 118.33 ? 56  ALA L O   1 
ATOM 1387 C CB  . ALA B 2 56  ? 292.532 355.969 480.065 1.00 118.33 ? 56  ALA L CB  1 
ATOM 1388 N N   . SER B 2 57  ? 295.248 356.791 479.482 1.00 129.18 ? 57  SER L N   1 
ATOM 1389 C CA  . SER B 2 57  ? 296.567 357.345 479.745 1.00 129.18 ? 57  SER L CA  1 
ATOM 1390 C C   . SER B 2 57  ? 296.634 357.848 481.179 1.00 129.18 ? 57  SER L C   1 
ATOM 1391 O O   . SER B 2 57  ? 295.781 358.631 481.609 1.00 129.18 ? 57  SER L O   1 
ATOM 1392 C CB  . SER B 2 57  ? 296.878 358.481 478.774 1.00 129.18 ? 57  SER L CB  1 
ATOM 1393 O OG  . SER B 2 57  ? 296.219 359.670 479.169 1.00 129.18 ? 57  SER L OG  1 
ATOM 1394 N N   . GLY B 2 58  ? 297.648 357.402 481.915 1.00 129.34 ? 58  GLY L N   1 
ATOM 1395 C CA  . GLY B 2 58  ? 297.835 357.835 483.280 1.00 129.34 ? 58  GLY L CA  1 
ATOM 1396 C C   . GLY B 2 58  ? 297.037 357.079 484.316 1.00 129.34 ? 58  GLY L C   1 
ATOM 1397 O O   . GLY B 2 58  ? 296.993 357.511 485.473 1.00 129.34 ? 58  GLY L O   1 
ATOM 1398 N N   . VAL B 2 59  ? 296.395 355.980 483.943 1.00 126.25 ? 59  VAL L N   1 
ATOM 1399 C CA  . VAL B 2 59  ? 295.652 355.150 484.886 1.00 126.25 ? 59  VAL L CA  1 
ATOM 1400 C C   . VAL B 2 59  ? 296.607 354.089 485.429 1.00 126.25 ? 59  VAL L C   1 
ATOM 1401 O O   . VAL B 2 59  ? 297.532 353.673 484.716 1.00 126.25 ? 59  VAL L O   1 
ATOM 1402 C CB  . VAL B 2 59  ? 294.394 354.573 484.209 1.00 126.25 ? 59  VAL L CB  1 
ATOM 1403 C CG1 . VAL B 2 59  ? 294.756 353.617 483.111 1.00 126.25 ? 59  VAL L CG1 1 
ATOM 1404 C CG2 . VAL B 2 59  ? 293.478 353.887 485.197 1.00 126.25 ? 59  VAL L CG2 1 
ATOM 1405 N N   . PRO B 2 60  ? 296.498 353.697 486.697 1.00 127.77 ? 60  PRO L N   1 
ATOM 1406 C CA  . PRO B 2 60  ? 297.323 352.593 487.197 1.00 127.77 ? 60  PRO L CA  1 
ATOM 1407 C C   . PRO B 2 60  ? 296.931 351.266 486.573 1.00 127.77 ? 60  PRO L C   1 
ATOM 1408 O O   . PRO B 2 60  ? 295.837 351.094 486.034 1.00 127.77 ? 60  PRO L O   1 
ATOM 1409 C CB  . PRO B 2 60  ? 297.045 352.594 488.701 1.00 127.77 ? 60  PRO L CB  1 
ATOM 1410 C CG  . PRO B 2 60  ? 296.669 353.984 489.001 1.00 127.77 ? 60  PRO L CG  1 
ATOM 1411 C CD  . PRO B 2 60  ? 295.928 354.486 487.802 1.00 127.77 ? 60  PRO L CD  1 
ATOM 1412 N N   . ALA B 2 61  ? 297.850 350.310 486.669 1.00 128.09 ? 61  ALA L N   1 
ATOM 1413 C CA  . ALA B 2 61  ? 297.689 349.016 486.020 1.00 128.09 ? 61  ALA L CA  1 
ATOM 1414 C C   . ALA B 2 61  ? 296.886 348.020 486.844 1.00 128.09 ? 61  ALA L C   1 
ATOM 1415 O O   . ALA B 2 61  ? 296.827 346.844 486.470 1.00 128.09 ? 61  ALA L O   1 
ATOM 1416 C CB  . ALA B 2 61  ? 299.059 348.423 485.695 1.00 128.09 ? 61  ALA L CB  1 
ATOM 1417 N N   . ARG B 2 62  ? 296.275 348.445 487.949 1.00 132.33 ? 62  ARG L N   1 
ATOM 1418 C CA  . ARG B 2 62  ? 295.476 347.519 488.738 1.00 132.33 ? 62  ARG L CA  1 
ATOM 1419 C C   . ARG B 2 62  ? 294.122 347.263 488.097 1.00 132.33 ? 62  ARG L C   1 
ATOM 1420 O O   . ARG B 2 62  ? 293.543 346.187 488.279 1.00 132.33 ? 62  ARG L O   1 
ATOM 1421 C CB  . ARG B 2 62  ? 295.294 348.058 490.154 1.00 132.33 ? 62  ARG L CB  1 
ATOM 1422 C CG  . ARG B 2 62  ? 296.548 348.663 490.736 1.00 132.33 ? 62  ARG L CG  1 
ATOM 1423 C CD  . ARG B 2 62  ? 296.348 349.033 492.186 1.00 132.33 ? 62  ARG L CD  1 
ATOM 1424 N NE  . ARG B 2 62  ? 295.228 349.948 492.363 1.00 132.33 ? 62  ARG L NE  1 
ATOM 1425 C CZ  . ARG B 2 62  ? 295.342 351.271 492.356 1.00 132.33 ? 62  ARG L CZ  1 
ATOM 1426 N NH1 . ARG B 2 62  ? 296.528 351.833 492.184 1.00 132.33 ? 62  ARG L NH1 1 
ATOM 1427 N NH2 . ARG B 2 62  ? 294.269 352.030 492.526 1.00 132.33 ? 62  ARG L NH2 1 
ATOM 1428 N N   . PHE B 2 63  ? 293.605 348.228 487.349 1.00 125.27 ? 63  PHE L N   1 
ATOM 1429 C CA  . PHE B 2 63  ? 292.287 348.084 486.749 1.00 125.27 ? 63  PHE L CA  1 
ATOM 1430 C C   . PHE B 2 63  ? 292.365 347.244 485.485 1.00 125.27 ? 63  PHE L C   1 
ATOM 1431 O O   . PHE B 2 63  ? 293.328 347.330 484.720 1.00 125.27 ? 63  PHE L O   1 
ATOM 1432 C CB  . PHE B 2 63  ? 291.705 349.452 486.421 1.00 125.27 ? 63  PHE L CB  1 
ATOM 1433 C CG  . PHE B 2 63  ? 291.471 350.311 487.618 1.00 125.27 ? 63  PHE L CG  1 
ATOM 1434 C CD1 . PHE B 2 63  ? 290.273 350.245 488.301 1.00 125.27 ? 63  PHE L CD1 1 
ATOM 1435 C CD2 . PHE B 2 63  ? 292.442 351.193 488.052 1.00 125.27 ? 63  PHE L CD2 1 
ATOM 1436 C CE1 . PHE B 2 63  ? 290.051 351.037 489.399 1.00 125.27 ? 63  PHE L CE1 1 
ATOM 1437 C CE2 . PHE B 2 63  ? 292.225 351.987 489.152 1.00 125.27 ? 63  PHE L CE2 1 
ATOM 1438 C CZ  . PHE B 2 63  ? 291.029 351.910 489.826 1.00 125.27 ? 63  PHE L CZ  1 
ATOM 1439 N N   . SER B 2 64  ? 291.335 346.435 485.261 1.00 122.40 ? 64  SER L N   1 
ATOM 1440 C CA  . SER B 2 64  ? 291.251 345.619 484.055 1.00 122.40 ? 64  SER L CA  1 
ATOM 1441 C C   . SER B 2 64  ? 289.792 345.300 483.792 1.00 122.40 ? 64  SER L C   1 
ATOM 1442 O O   . SER B 2 64  ? 289.107 344.773 484.672 1.00 122.40 ? 64  SER L O   1 
ATOM 1443 C CB  . SER B 2 64  ? 292.063 344.334 484.202 1.00 122.40 ? 64  SER L CB  1 
ATOM 1444 O OG  . SER B 2 64  ? 291.443 343.449 485.112 1.00 122.40 ? 64  SER L OG  1 
ATOM 1445 N N   . GLY B 2 65  ? 289.315 345.628 482.599 1.00 117.70 ? 65  GLY L N   1 
ATOM 1446 C CA  . GLY B 2 65  ? 287.973 345.289 482.194 1.00 117.70 ? 65  GLY L CA  1 
ATOM 1447 C C   . GLY B 2 65  ? 287.958 344.042 481.333 1.00 117.70 ? 65  GLY L C   1 
ATOM 1448 O O   . GLY B 2 65  ? 288.976 343.634 480.784 1.00 117.70 ? 65  GLY L O   1 
ATOM 1449 N N   . SER B 2 66  ? 286.784 343.435 481.225 1.00 116.55 ? 66  SER L N   1 
ATOM 1450 C CA  . SER B 2 66  ? 286.612 342.222 480.438 1.00 116.55 ? 66  SER L CA  1 
ATOM 1451 C C   . SER B 2 66  ? 285.143 342.108 480.057 1.00 116.55 ? 66  SER L C   1 
ATOM 1452 O O   . SER B 2 66  ? 284.364 343.050 480.233 1.00 116.55 ? 66  SER L O   1 
ATOM 1453 C CB  . SER B 2 66  ? 287.082 340.991 481.216 1.00 116.55 ? 66  SER L CB  1 
ATOM 1454 O OG  . SER B 2 66  ? 286.031 340.478 482.013 1.00 116.55 ? 66  SER L OG  1 
ATOM 1455 N N   . GLY B 2 67  ? 284.762 340.950 479.538 1.00 119.77 ? 67  GLY L N   1 
ATOM 1456 C CA  . GLY B 2 67  ? 283.381 340.678 479.208 1.00 119.77 ? 67  GLY L CA  1 
ATOM 1457 C C   . GLY B 2 67  ? 283.071 340.956 477.750 1.00 119.77 ? 67  GLY L C   1 
ATOM 1458 O O   . GLY B 2 67  ? 283.786 341.673 477.047 1.00 119.77 ? 67  GLY L O   1 
ATOM 1459 N N   . SER B 2 68  ? 281.971 340.367 477.298 1.00 123.62 ? 68  SER L N   1 
ATOM 1460 C CA  . SER B 2 68  ? 281.529 340.512 475.919 1.00 123.62 ? 68  SER L CA  1 
ATOM 1461 C C   . SER B 2 68  ? 280.031 340.265 475.865 1.00 123.62 ? 68  SER L C   1 
ATOM 1462 O O   . SER B 2 68  ? 279.397 339.944 476.872 1.00 123.62 ? 68  SER L O   1 
ATOM 1463 C CB  . SER B 2 68  ? 282.264 339.547 474.992 1.00 123.62 ? 68  SER L CB  1 
ATOM 1464 O OG  . SER B 2 68  ? 281.906 338.210 475.291 1.00 123.62 ? 68  SER L OG  1 
ATOM 1465 N N   . GLY B 2 69  ? 279.474 340.414 474.669 1.00 119.37 ? 69  GLY L N   1 
ATOM 1466 C CA  . GLY B 2 69  ? 278.064 340.156 474.468 1.00 119.37 ? 69  GLY L CA  1 
ATOM 1467 C C   . GLY B 2 69  ? 277.190 341.241 475.052 1.00 119.37 ? 69  GLY L C   1 
ATOM 1468 O O   . GLY B 2 69  ? 277.160 342.362 474.540 1.00 119.37 ? 69  GLY L O   1 
ATOM 1469 N N   . THR B 2 70  ? 276.475 340.923 476.127 1.00 122.56 ? 70  THR L N   1 
ATOM 1470 C CA  . THR B 2 70  ? 275.603 341.883 476.783 1.00 122.56 ? 70  THR L CA  1 
ATOM 1471 C C   . THR B 2 70  ? 275.927 342.083 478.254 1.00 122.56 ? 70  THR L C   1 
ATOM 1472 O O   . THR B 2 70  ? 275.202 342.811 478.936 1.00 122.56 ? 70  THR L O   1 
ATOM 1473 C CB  . THR B 2 70  ? 274.142 341.452 476.647 1.00 122.56 ? 70  THR L CB  1 
ATOM 1474 O OG1 . THR B 2 70  ? 273.317 342.335 477.414 1.00 122.56 ? 70  THR L OG1 1 
ATOM 1475 C CG2 . THR B 2 70  ? 273.967 340.041 477.154 1.00 122.56 ? 70  THR L CG2 1 
ATOM 1476 N N   . SER B 2 71  ? 276.983 341.456 478.765 1.00 121.09 ? 71  SER L N   1 
ATOM 1477 C CA  . SER B 2 71  ? 277.374 341.586 480.161 1.00 121.09 ? 71  SER L CA  1 
ATOM 1478 C C   . SER B 2 71  ? 278.864 341.869 480.236 1.00 121.09 ? 71  SER L C   1 
ATOM 1479 O O   . SER B 2 71  ? 279.676 341.054 479.788 1.00 121.09 ? 71  SER L O   1 
ATOM 1480 C CB  . SER B 2 71  ? 277.036 340.324 480.947 1.00 121.09 ? 71  SER L CB  1 
ATOM 1481 O OG  . SER B 2 71  ? 277.471 340.444 482.287 1.00 121.09 ? 71  SER L OG  1 
ATOM 1482 N N   . TYR B 2 72  ? 279.219 343.009 480.816 1.00 117.18 ? 72  TYR L N   1 
ATOM 1483 C CA  . TYR B 2 72  ? 280.603 343.436 480.924 1.00 117.18 ? 72  TYR L CA  1 
ATOM 1484 C C   . TYR B 2 72  ? 280.934 343.661 482.388 1.00 117.18 ? 72  TYR L C   1 
ATOM 1485 O O   . TYR B 2 72  ? 280.048 343.864 483.219 1.00 117.18 ? 72  TYR L O   1 
ATOM 1486 C CB  . TYR B 2 72  ? 280.860 344.714 480.126 1.00 117.18 ? 72  TYR L CB  1 
ATOM 1487 C CG  . TYR B 2 72  ? 280.710 344.540 478.638 1.00 117.18 ? 72  TYR L CG  1 
ATOM 1488 C CD1 . TYR B 2 72  ? 279.470 344.628 478.031 1.00 117.18 ? 72  TYR L CD1 1 
ATOM 1489 C CD2 . TYR B 2 72  ? 281.809 344.278 477.843 1.00 117.18 ? 72  TYR L CD2 1 
ATOM 1490 C CE1 . TYR B 2 72  ? 279.333 344.469 476.675 1.00 117.18 ? 72  TYR L CE1 1 
ATOM 1491 C CE2 . TYR B 2 72  ? 281.682 344.119 476.485 1.00 117.18 ? 72  TYR L CE2 1 
ATOM 1492 C CZ  . TYR B 2 72  ? 280.441 344.213 475.908 1.00 117.18 ? 72  TYR L CZ  1 
ATOM 1493 O OH  . TYR B 2 72  ? 280.308 344.052 474.552 1.00 117.18 ? 72  TYR L OH  1 
ATOM 1494 N N   . SER B 2 73  ? 282.225 343.632 482.702 1.00 116.28 ? 73  SER L N   1 
ATOM 1495 C CA  . SER B 2 73  ? 282.635 343.690 484.094 1.00 116.28 ? 73  SER L CA  1 
ATOM 1496 C C   . SER B 2 73  ? 283.948 344.439 484.222 1.00 116.28 ? 73  SER L C   1 
ATOM 1497 O O   . SER B 2 73  ? 284.804 344.379 483.340 1.00 116.28 ? 73  SER L O   1 
ATOM 1498 C CB  . SER B 2 73  ? 282.787 342.291 484.682 1.00 116.28 ? 73  SER L CB  1 
ATOM 1499 O OG  . SER B 2 73  ? 283.715 341.540 483.923 1.00 116.28 ? 73  SER L OG  1 
ATOM 1500 N N   . LEU B 2 74  ? 284.096 345.135 485.342 1.00 121.52 ? 74  LEU L N   1 
ATOM 1501 C CA  . LEU B 2 74  ? 285.326 345.823 485.695 1.00 121.52 ? 74  LEU L CA  1 
ATOM 1502 C C   . LEU B 2 74  ? 285.779 345.328 487.056 1.00 121.52 ? 74  LEU L C   1 
ATOM 1503 O O   . LEU B 2 74  ? 285.038 345.446 488.036 1.00 121.52 ? 74  LEU L O   1 
ATOM 1504 C CB  . LEU B 2 74  ? 285.126 347.335 485.726 1.00 121.52 ? 74  LEU L CB  1 
ATOM 1505 C CG  . LEU B 2 74  ? 286.252 348.148 486.356 1.00 121.52 ? 74  LEU L CG  1 
ATOM 1506 C CD1 . LEU B 2 74  ? 287.535 347.959 485.587 1.00 121.52 ? 74  LEU L CD1 1 
ATOM 1507 C CD2 . LEU B 2 74  ? 285.878 349.606 486.394 1.00 121.52 ? 74  LEU L CD2 1 
ATOM 1508 N N   . THR B 2 75  ? 286.989 344.784 487.115 1.00 128.33 ? 75  THR L N   1 
ATOM 1509 C CA  . THR B 2 75  ? 287.528 344.214 488.339 1.00 128.33 ? 75  THR L CA  1 
ATOM 1510 C C   . THR B 2 75  ? 288.806 344.935 488.739 1.00 128.33 ? 75  THR L C   1 
ATOM 1511 O O   . THR B 2 75  ? 289.645 345.248 487.890 1.00 128.33 ? 75  THR L O   1 
ATOM 1512 C CB  . THR B 2 75  ? 287.780 342.710 488.185 1.00 128.33 ? 75  THR L CB  1 
ATOM 1513 O OG1 . THR B 2 75  ? 288.568 342.241 489.284 1.00 128.33 ? 75  THR L OG1 1 
ATOM 1514 C CG2 . THR B 2 75  ? 288.464 342.385 486.870 1.00 128.33 ? 75  THR L CG2 1 
ATOM 1515 N N   . ILE B 2 76  ? 288.931 345.218 490.031 1.00 133.92 ? 76  ILE L N   1 
ATOM 1516 C CA  . ILE B 2 76  ? 290.115 345.844 490.603 1.00 133.92 ? 76  ILE L CA  1 
ATOM 1517 C C   . ILE B 2 76  ? 290.910 344.756 491.304 1.00 133.92 ? 76  ILE L C   1 
ATOM 1518 O O   . ILE B 2 76  ? 290.353 343.995 492.103 1.00 133.92 ? 76  ILE L O   1 
ATOM 1519 C CB  . ILE B 2 76  ? 289.742 346.965 491.580 1.00 133.92 ? 76  ILE L CB  1 
ATOM 1520 C CG1 . ILE B 2 76  ? 288.733 347.908 490.936 1.00 133.92 ? 76  ILE L CG1 1 
ATOM 1521 C CG2 . ILE B 2 76  ? 290.975 347.719 492.016 1.00 133.92 ? 76  ILE L CG2 1 
ATOM 1522 C CD1 . ILE B 2 76  ? 288.233 348.971 491.870 1.00 133.92 ? 76  ILE L CD1 1 
ATOM 1523 N N   . SER B 2 77  ? 292.206 344.677 491.005 1.00 139.48 ? 77  SER L N   1 
ATOM 1524 C CA  . SER B 2 77  ? 293.037 343.631 491.591 1.00 139.48 ? 77  SER L CA  1 
ATOM 1525 C C   . SER B 2 77  ? 293.295 343.893 493.069 1.00 139.48 ? 77  SER L C   1 
ATOM 1526 O O   . SER B 2 77  ? 293.040 343.030 493.917 1.00 139.48 ? 77  SER L O   1 
ATOM 1527 C CB  . SER B 2 77  ? 294.351 343.520 490.823 1.00 139.48 ? 77  SER L CB  1 
ATOM 1528 O OG  . SER B 2 77  ? 294.119 343.551 489.427 1.00 139.48 ? 77  SER L OG  1 
ATOM 1529 N N   . SER B 2 78  ? 293.793 345.080 493.400 1.00 144.57 ? 78  SER L N   1 
ATOM 1530 C CA  . SER B 2 78  ? 294.044 345.469 494.779 1.00 144.57 ? 78  SER L CA  1 
ATOM 1531 C C   . SER B 2 78  ? 293.449 346.846 495.017 1.00 144.57 ? 78  SER L C   1 
ATOM 1532 O O   . SER B 2 78  ? 293.693 347.771 494.238 1.00 144.57 ? 78  SER L O   1 
ATOM 1533 C CB  . SER B 2 78  ? 295.541 345.476 495.088 1.00 144.57 ? 78  SER L CB  1 
ATOM 1534 O OG  . SER B 2 78  ? 296.165 344.318 494.567 1.00 144.57 ? 78  SER L OG  1 
ATOM 1535 N N   . VAL B 2 79  ? 292.688 346.981 496.079 1.00 147.18 ? 79  VAL L N   1 
ATOM 1536 C CA  . VAL B 2 79  ? 292.007 348.231 496.383 1.00 147.18 ? 79  VAL L CA  1 
ATOM 1537 C C   . VAL B 2 79  ? 292.953 349.122 497.171 1.00 147.18 ? 79  VAL L C   1 
ATOM 1538 O O   . VAL B 2 79  ? 293.554 348.688 498.159 1.00 147.18 ? 79  VAL L O   1 
ATOM 1539 C CB  . VAL B 2 79  ? 290.710 347.964 497.165 1.00 147.18 ? 79  VAL L CB  1 
ATOM 1540 C CG1 . VAL B 2 79  ? 290.021 349.262 497.517 1.00 147.18 ? 79  VAL L CG1 1 
ATOM 1541 C CG2 . VAL B 2 79  ? 289.796 347.072 496.368 1.00 147.18 ? 79  VAL L CG2 1 
ATOM 1542 N N   . GLU B 2 80  ? 293.086 350.370 496.740 1.00 147.55 ? 80  GLU L N   1 
ATOM 1543 C CA  . GLU B 2 80  ? 293.927 351.358 497.401 1.00 147.55 ? 80  GLU L CA  1 
ATOM 1544 C C   . GLU B 2 80  ? 293.059 352.500 497.916 1.00 147.55 ? 80  GLU L C   1 
ATOM 1545 O O   . GLU B 2 80  ? 291.829 352.436 497.893 1.00 147.55 ? 80  GLU L O   1 
ATOM 1546 C CB  . GLU B 2 80  ? 295.016 351.884 496.462 1.00 147.55 ? 80  GLU L CB  1 
ATOM 1547 C CG  . GLU B 2 80  ? 295.903 350.821 495.833 1.00 147.55 ? 80  GLU L CG  1 
ATOM 1548 C CD  . GLU B 2 80  ? 296.275 349.707 496.789 1.00 147.55 ? 80  GLU L CD  1 
ATOM 1549 O OE1 . GLU B 2 80  ? 295.951 348.537 496.499 1.00 147.55 ? 80  GLU L OE1 1 
ATOM 1550 O OE2 . GLU B 2 80  ? 296.904 350.001 497.828 1.00 147.55 ? 80  GLU L OE2 1 
ATOM 1551 N N   . ALA B 2 81  ? 293.718 353.550 498.397 1.00 149.11 ? 81  ALA L N   1 
ATOM 1552 C CA  . ALA B 2 81  ? 293.022 354.619 499.096 1.00 149.11 ? 81  ALA L CA  1 
ATOM 1553 C C   . ALA B 2 81  ? 292.513 355.723 498.181 1.00 149.11 ? 81  ALA L C   1 
ATOM 1554 O O   . ALA B 2 81  ? 291.694 356.534 498.623 1.00 149.11 ? 81  ALA L O   1 
ATOM 1555 C CB  . ALA B 2 81  ? 293.936 355.233 500.156 1.00 149.11 ? 81  ALA L CB  1 
ATOM 1556 N N   . GLU B 2 82  ? 292.966 355.782 496.931 1.00 146.05 ? 82  GLU L N   1 
ATOM 1557 C CA  . GLU B 2 82  ? 292.548 356.864 496.050 1.00 146.05 ? 82  GLU L CA  1 
ATOM 1558 C C   . GLU B 2 82  ? 291.466 356.444 495.070 1.00 146.05 ? 82  GLU L C   1 
ATOM 1559 O O   . GLU B 2 82  ? 290.924 357.296 494.359 1.00 146.05 ? 82  GLU L O   1 
ATOM 1560 C CB  . GLU B 2 82  ? 293.750 357.415 495.275 1.00 146.05 ? 82  GLU L CB  1 
ATOM 1561 C CG  . GLU B 2 82  ? 294.140 356.614 494.036 1.00 146.05 ? 82  GLU L CG  1 
ATOM 1562 C CD  . GLU B 2 82  ? 294.836 355.298 494.346 1.00 146.05 ? 82  GLU L CD  1 
ATOM 1563 O OE1 . GLU B 2 82  ? 295.067 354.520 493.397 1.00 146.05 ? 82  GLU L OE1 1 
ATOM 1564 O OE2 . GLU B 2 82  ? 295.195 355.055 495.517 1.00 146.05 ? 82  GLU L OE2 1 
ATOM 1565 N N   . ASP B 2 83  ? 291.127 355.160 495.020 1.00 144.34 ? 83  ASP L N   1 
ATOM 1566 C CA  . ASP B 2 83  ? 290.151 354.649 494.063 1.00 144.34 ? 83  ASP L CA  1 
ATOM 1567 C C   . ASP B 2 83  ? 288.789 354.426 494.703 1.00 144.34 ? 83  ASP L C   1 
ATOM 1568 O O   . ASP B 2 83  ? 288.113 353.433 494.428 1.00 144.34 ? 83  ASP L O   1 
ATOM 1569 C CB  . ASP B 2 83  ? 290.666 353.371 493.414 1.00 144.34 ? 83  ASP L CB  1 
ATOM 1570 C CG  . ASP B 2 83  ? 291.224 352.398 494.417 1.00 144.34 ? 83  ASP L CG  1 
ATOM 1571 O OD1 . ASP B 2 83  ? 290.442 351.833 495.208 1.00 144.34 ? 83  ASP L OD1 1 
ATOM 1572 O OD2 . ASP B 2 83  ? 292.454 352.194 494.410 1.00 144.34 ? 83  ASP L OD2 1 
ATOM 1573 N N   . ALA B 2 84  ? 288.377 355.332 495.581 1.00 141.12 ? 84  ALA L N   1 
ATOM 1574 C CA  . ALA B 2 84  ? 287.025 355.327 496.128 1.00 141.12 ? 84  ALA L CA  1 
ATOM 1575 C C   . ALA B 2 84  ? 286.241 356.436 495.439 1.00 141.12 ? 84  ALA L C   1 
ATOM 1576 O O   . ALA B 2 84  ? 286.331 357.604 495.822 1.00 141.12 ? 84  ALA L O   1 
ATOM 1577 C CB  . ALA B 2 84  ? 287.055 355.516 497.639 1.00 141.12 ? 84  ALA L CB  1 
ATOM 1578 N N   . ALA B 2 85  ? 285.473 356.075 494.416 1.00 131.77 ? 85  ALA L N   1 
ATOM 1579 C CA  . ALA B 2 85  ? 284.712 357.045 493.641 1.00 131.77 ? 85  ALA L CA  1 
ATOM 1580 C C   . ALA B 2 85  ? 283.525 356.329 493.010 1.00 131.77 ? 85  ALA L C   1 
ATOM 1581 O O   . ALA B 2 85  ? 283.181 355.208 493.394 1.00 131.77 ? 85  ALA L O   1 
ATOM 1582 C CB  . ALA B 2 85  ? 285.598 357.719 492.591 1.00 131.77 ? 85  ALA L CB  1 
ATOM 1583 N N   . THR B 2 86  ? 282.891 356.983 492.043 1.00 126.31 ? 86  THR L N   1 
ATOM 1584 C CA  . THR B 2 86  ? 281.731 356.446 491.350 1.00 126.31 ? 86  THR L CA  1 
ATOM 1585 C C   . THR B 2 86  ? 282.107 356.092 489.921 1.00 126.31 ? 86  THR L C   1 
ATOM 1586 O O   . THR B 2 86  ? 282.741 356.889 489.225 1.00 126.31 ? 86  THR L O   1 
ATOM 1587 C CB  . THR B 2 86  ? 280.586 357.456 491.340 1.00 126.31 ? 86  THR L CB  1 
ATOM 1588 O OG1 . THR B 2 86  ? 280.507 358.099 492.616 1.00 126.31 ? 86  THR L OG1 1 
ATOM 1589 C CG2 . THR B 2 86  ? 279.272 356.758 491.055 1.00 126.31 ? 86  THR L CG2 1 
ATOM 1590 N N   . TYR B 2 87  ? 281.710 354.903 489.478 1.00 122.38 ? 87  TYR L N   1 
ATOM 1591 C CA  . TYR B 2 87  ? 282.081 354.397 488.163 1.00 122.38 ? 87  TYR L CA  1 
ATOM 1592 C C   . TYR B 2 87  ? 280.838 354.238 487.303 1.00 122.38 ? 87  TYR L C   1 
ATOM 1593 O O   . TYR B 2 87  ? 279.863 353.609 487.724 1.00 122.38 ? 87  TYR L O   1 
ATOM 1594 C CB  . TYR B 2 87  ? 282.820 353.067 488.283 1.00 122.38 ? 87  TYR L CB  1 
ATOM 1595 C CG  . TYR B 2 87  ? 284.132 353.180 489.008 1.00 122.38 ? 87  TYR L CG  1 
ATOM 1596 C CD1 . TYR B 2 87  ? 285.288 353.522 488.331 1.00 122.38 ? 87  TYR L CD1 1 
ATOM 1597 C CD2 . TYR B 2 87  ? 284.214 352.949 490.369 1.00 122.38 ? 87  TYR L CD2 1 
ATOM 1598 C CE1 . TYR B 2 87  ? 286.492 353.626 488.989 1.00 122.38 ? 87  TYR L CE1 1 
ATOM 1599 C CE2 . TYR B 2 87  ? 285.413 353.055 491.035 1.00 122.38 ? 87  TYR L CE2 1 
ATOM 1600 C CZ  . TYR B 2 87  ? 286.546 353.395 490.338 1.00 122.38 ? 87  TYR L CZ  1 
ATOM 1601 O OH  . TYR B 2 87  ? 287.746 353.502 490.992 1.00 122.38 ? 87  TYR L OH  1 
ATOM 1602 N N   . TYR B 2 88  ? 280.878 354.801 486.101 1.00 117.57 ? 88  TYR L N   1 
ATOM 1603 C CA  . TYR B 2 88  ? 279.811 354.669 485.123 1.00 117.57 ? 88  TYR L CA  1 
ATOM 1604 C C   . TYR B 2 88  ? 280.294 353.838 483.946 1.00 117.57 ? 88  TYR L C   1 
ATOM 1605 O O   . TYR B 2 88  ? 281.491 353.775 483.665 1.00 117.57 ? 88  TYR L O   1 
ATOM 1606 C CB  . TYR B 2 88  ? 279.353 356.033 484.615 1.00 117.57 ? 88  TYR L CB  1 
ATOM 1607 C CG  . TYR B 2 88  ? 278.875 356.973 485.685 1.00 117.57 ? 88  TYR L CG  1 
ATOM 1608 C CD1 . TYR B 2 88  ? 277.555 356.955 486.107 1.00 117.57 ? 88  TYR L CD1 1 
ATOM 1609 C CD2 . TYR B 2 88  ? 279.735 357.892 486.260 1.00 117.57 ? 88  TYR L CD2 1 
ATOM 1610 C CE1 . TYR B 2 88  ? 277.108 357.820 487.081 1.00 117.57 ? 88  TYR L CE1 1 
ATOM 1611 C CE2 . TYR B 2 88  ? 279.299 358.759 487.235 1.00 117.57 ? 88  TYR L CE2 1 
ATOM 1612 C CZ  . TYR B 2 88  ? 277.985 358.717 487.640 1.00 117.57 ? 88  TYR L CZ  1 
ATOM 1613 O OH  . TYR B 2 88  ? 277.544 359.580 488.612 1.00 117.57 ? 88  TYR L OH  1 
ATOM 1614 N N   . CYS B 2 89  ? 279.356 353.203 483.252 1.00 117.29 ? 89  CYS L N   1 
ATOM 1615 C CA  . CYS B 2 89  ? 279.649 352.546 481.989 1.00 117.29 ? 89  CYS L CA  1 
ATOM 1616 C C   . CYS B 2 89  ? 278.810 353.186 480.897 1.00 117.29 ? 89  CYS L C   1 
ATOM 1617 O O   . CYS B 2 89  ? 277.670 353.590 481.136 1.00 117.29 ? 89  CYS L O   1 
ATOM 1618 C CB  . CYS B 2 89  ? 279.393 351.034 482.048 1.00 117.29 ? 89  CYS L CB  1 
ATOM 1619 S SG  . CYS B 2 89  ? 277.769 350.514 482.626 1.00 117.29 ? 89  CYS L SG  1 
ATOM 1620 N N   . GLN B 2 90  ? 279.385 353.292 479.705 1.00 109.28 ? 90  GLN L N   1 
ATOM 1621 C CA  . GLN B 2 90  ? 278.754 353.920 478.557 1.00 109.28 ? 90  GLN L CA  1 
ATOM 1622 C C   . GLN B 2 90  ? 278.607 352.894 477.444 1.00 109.28 ? 90  GLN L C   1 
ATOM 1623 O O   . GLN B 2 90  ? 279.321 351.893 477.407 1.00 109.28 ? 90  GLN L O   1 
ATOM 1624 C CB  . GLN B 2 90  ? 279.583 355.110 478.074 1.00 109.28 ? 90  GLN L CB  1 
ATOM 1625 C CG  . GLN B 2 90  ? 278.831 356.130 477.263 1.00 109.28 ? 90  GLN L CG  1 
ATOM 1626 C CD  . GLN B 2 90  ? 279.753 356.976 476.428 1.00 109.28 ? 90  GLN L CD  1 
ATOM 1627 O OE1 . GLN B 2 90  ? 280.925 357.133 476.751 1.00 109.28 ? 90  GLN L OE1 1 
ATOM 1628 N NE2 . GLN B 2 90  ? 279.234 357.516 475.338 1.00 109.28 ? 90  GLN L NE2 1 
ATOM 1629 N N   . GLN B 2 91  ? 277.670 353.135 476.533 1.00 107.63 ? 91  GLN L N   1 
ATOM 1630 C CA  . GLN B 2 91  ? 277.455 352.234 475.414 1.00 107.63 ? 91  GLN L CA  1 
ATOM 1631 C C   . GLN B 2 91  ? 277.079 353.030 474.179 1.00 107.63 ? 91  GLN L C   1 
ATOM 1632 O O   . GLN B 2 91  ? 276.794 354.225 474.248 1.00 107.63 ? 91  GLN L O   1 
ATOM 1633 C CB  . GLN B 2 91  ? 276.357 351.220 475.718 1.00 107.63 ? 91  GLN L CB  1 
ATOM 1634 C CG  . GLN B 2 91  ? 275.009 351.860 475.935 1.00 107.63 ? 91  GLN L CG  1 
ATOM 1635 C CD  . GLN B 2 91  ? 274.100 351.751 474.732 1.00 107.63 ? 91  GLN L CD  1 
ATOM 1636 O OE1 . GLN B 2 91  ? 274.206 350.816 473.944 1.00 107.63 ? 91  GLN L OE1 1 
ATOM 1637 N NE2 . GLN B 2 91  ? 273.203 352.713 474.582 1.00 107.63 ? 91  GLN L NE2 1 
ATOM 1638 N N   . PHE B 2 92  ? 277.064 352.340 473.041 1.00 101.66 ? 92  PHE L N   1 
ATOM 1639 C CA  . PHE B 2 92  ? 276.451 352.875 471.829 1.00 101.66 ? 92  PHE L CA  1 
ATOM 1640 C C   . PHE B 2 92  ? 276.043 351.710 470.942 1.00 101.66 ? 92  PHE L C   1 
ATOM 1641 O O   . PHE B 2 92  ? 276.904 351.042 470.365 1.00 101.66 ? 92  PHE L O   1 
ATOM 1642 C CB  . PHE B 2 92  ? 277.391 353.802 471.083 1.00 101.66 ? 92  PHE L CB  1 
ATOM 1643 C CG  . PHE B 2 92  ? 276.935 354.112 469.691 1.00 101.66 ? 92  PHE L CG  1 
ATOM 1644 C CD1 . PHE B 2 92  ? 275.709 354.703 469.462 1.00 101.66 ? 92  PHE L CD1 1 
ATOM 1645 C CD2 . PHE B 2 92  ? 277.725 353.797 468.611 1.00 101.66 ? 92  PHE L CD2 1 
ATOM 1646 C CE1 . PHE B 2 92  ? 275.292 354.977 468.185 1.00 101.66 ? 92  PHE L CE1 1 
ATOM 1647 C CE2 . PHE B 2 92  ? 277.305 354.073 467.332 1.00 101.66 ? 92  PHE L CE2 1 
ATOM 1648 C CZ  . PHE B 2 92  ? 276.090 354.661 467.123 1.00 101.66 ? 92  PHE L CZ  1 
ATOM 1649 N N   . SER B 2 93  ? 274.745 351.480 470.830 0.00 103.95 ? 93  SER L N   1 
ATOM 1650 C CA  . SER B 2 93  ? 274.188 350.642 469.785 0.00 103.95 ? 93  SER L CA  1 
ATOM 1651 C C   . SER B 2 93  ? 273.408 351.436 468.757 0.00 103.95 ? 93  SER L C   1 
ATOM 1652 O O   . SER B 2 93  ? 273.514 351.156 467.564 0.00 103.95 ? 93  SER L O   1 
ATOM 1653 C CB  . SER B 2 93  ? 273.271 349.575 470.388 0.00 103.95 ? 93  SER L CB  1 
ATOM 1654 O OG  . SER B 2 93  ? 272.299 350.175 471.220 0.00 103.95 ? 93  SER L OG  1 
ATOM 1655 N N   . GLY B 2 94  ? 272.626 352.412 469.196 1.00 103.39 ? 94  GLY L N   1 
ATOM 1656 C CA  . GLY B 2 94  ? 272.055 353.421 468.331 1.00 103.39 ? 94  GLY L CA  1 
ATOM 1657 C C   . GLY B 2 94  ? 272.018 354.695 469.142 1.00 103.39 ? 94  GLY L C   1 
ATOM 1658 O O   . GLY B 2 94  ? 272.283 354.682 470.345 1.00 103.39 ? 94  GLY L O   1 
ATOM 1659 N N   . TYR B 2 95  ? 271.715 355.799 468.477 1.00 100.10 ? 95  TYR L N   1 
ATOM 1660 C CA  . TYR B 2 95  ? 271.611 357.061 469.190 1.00 100.10 ? 95  TYR L CA  1 
ATOM 1661 C C   . TYR B 2 95  ? 270.388 357.037 470.103 1.00 100.10 ? 95  TYR L C   1 
ATOM 1662 O O   . TYR B 2 95  ? 269.347 356.494 469.728 1.00 100.10 ? 95  TYR L O   1 
ATOM 1663 C CB  . TYR B 2 95  ? 271.514 358.224 468.212 1.00 100.10 ? 95  TYR L CB  1 
ATOM 1664 C CG  . TYR B 2 95  ? 272.814 358.549 467.536 1.00 100.10 ? 95  TYR L CG  1 
ATOM 1665 C CD1 . TYR B 2 95  ? 273.802 359.248 468.199 1.00 100.10 ? 95  TYR L CD1 1 
ATOM 1666 C CD2 . TYR B 2 95  ? 273.049 358.168 466.230 1.00 100.10 ? 95  TYR L CD2 1 
ATOM 1667 C CE1 . TYR B 2 95  ? 274.986 359.550 467.586 1.00 100.10 ? 95  TYR L CE1 1 
ATOM 1668 C CE2 . TYR B 2 95  ? 274.233 358.469 465.609 1.00 100.10 ? 95  TYR L CE2 1 
ATOM 1669 C CZ  . TYR B 2 95  ? 275.194 359.157 466.293 1.00 100.10 ? 95  TYR L CZ  1 
ATOM 1670 O OH  . TYR B 2 95  ? 276.376 359.457 465.673 1.00 100.10 ? 95  TYR L OH  1 
ATOM 1671 N N   . PRO B 2 96  ? 270.479 357.603 471.311 1.00 100.08 ? 96  PRO L N   1 
ATOM 1672 C CA  . PRO B 2 96  ? 271.591 358.341 471.907 1.00 100.08 ? 96  PRO L CA  1 
ATOM 1673 C C   . PRO B 2 96  ? 272.579 357.473 472.673 1.00 100.08 ? 96  PRO L C   1 
ATOM 1674 O O   . PRO B 2 96  ? 272.386 356.269 472.774 1.00 100.08 ? 96  PRO L O   1 
ATOM 1675 C CB  . PRO B 2 96  ? 270.876 359.290 472.857 1.00 100.08 ? 96  PRO L CB  1 
ATOM 1676 C CG  . PRO B 2 96  ? 269.710 358.511 473.320 1.00 100.08 ? 96  PRO L CG  1 
ATOM 1677 C CD  . PRO B 2 96  ? 269.302 357.603 472.193 1.00 100.08 ? 96  PRO L CD  1 
ATOM 1678 N N   . LEU B 2 97  ? 273.625 358.096 473.208 1.00 102.40 ? 97  LEU L N   1 
ATOM 1679 C CA  . LEU B 2 97  ? 274.595 357.415 474.053 1.00 102.40 ? 97  LEU L CA  1 
ATOM 1680 C C   . LEU B 2 97  ? 274.085 357.432 475.486 1.00 102.40 ? 97  LEU L C   1 
ATOM 1681 O O   . LEU B 2 97  ? 274.026 358.494 476.111 1.00 102.40 ? 97  LEU L O   1 
ATOM 1682 C CB  . LEU B 2 97  ? 275.957 358.097 473.985 1.00 102.40 ? 97  LEU L CB  1 
ATOM 1683 C CG  . LEU B 2 97  ? 276.473 358.552 472.625 1.00 102.40 ? 97  LEU L CG  1 
ATOM 1684 C CD1 . LEU B 2 97  ? 277.787 359.273 472.782 1.00 102.40 ? 97  LEU L CD1 1 
ATOM 1685 C CD2 . LEU B 2 97  ? 276.636 357.378 471.719 1.00 102.40 ? 97  LEU L CD2 1 
ATOM 1686 N N   . THR B 2 98  ? 273.727 356.272 476.008 1.00 108.79 ? 98  THR L N   1 
ATOM 1687 C CA  . THR B 2 98  ? 273.186 356.177 477.353 1.00 108.79 ? 98  THR L CA  1 
ATOM 1688 C C   . THR B 2 98  ? 274.289 355.827 478.336 1.00 108.79 ? 98  THR L C   1 
ATOM 1689 O O   . THR B 2 98  ? 275.104 354.939 478.076 1.00 108.79 ? 98  THR L O   1 
ATOM 1690 C CB  . THR B 2 98  ? 272.087 355.124 477.430 1.00 108.79 ? 98  THR L CB  1 
ATOM 1691 O OG1 . THR B 2 98  ? 272.633 353.849 477.083 1.00 108.79 ? 98  THR L OG1 1 
ATOM 1692 C CG2 . THR B 2 98  ? 270.965 355.461 476.476 1.00 108.79 ? 98  THR L CG2 1 
ATOM 1693 N N   . PHE B 2 99  ? 274.305 356.522 479.463 1.00 111.31 ? 99  PHE L N   1 
ATOM 1694 C CA  . PHE B 2 99  ? 275.214 356.215 480.551 1.00 111.31 ? 99  PHE L CA  1 
ATOM 1695 C C   . PHE B 2 99  ? 274.552 355.251 481.522 1.00 111.31 ? 99  PHE L C   1 
ATOM 1696 O O   . PHE B 2 99  ? 273.334 355.074 481.525 1.00 111.31 ? 99  PHE L O   1 
ATOM 1697 C CB  . PHE B 2 99  ? 275.626 357.484 481.289 1.00 111.31 ? 99  PHE L CB  1 
ATOM 1698 C CG  . PHE B 2 99  ? 276.607 358.323 480.545 1.00 111.31 ? 99  PHE L CG  1 
ATOM 1699 C CD1 . PHE B 2 99  ? 276.180 359.247 479.616 1.00 111.31 ? 99  PHE L CD1 1 
ATOM 1700 C CD2 . PHE B 2 99  ? 277.958 358.198 480.781 1.00 111.31 ? 99  PHE L CD2 1 
ATOM 1701 C CE1 . PHE B 2 99  ? 277.081 360.025 478.934 1.00 111.31 ? 99  PHE L CE1 1 
ATOM 1702 C CE2 . PHE B 2 99  ? 278.862 358.973 480.102 1.00 111.31 ? 99  PHE L CE2 1 
ATOM 1703 C CZ  . PHE B 2 99  ? 278.422 359.888 479.178 1.00 111.31 ? 99  PHE L CZ  1 
ATOM 1704 N N   . GLY B 2 100 ? 275.372 354.626 482.354 1.00 117.79 ? 100 GLY L N   1 
ATOM 1705 C CA  . GLY B 2 100 ? 274.868 353.718 483.356 1.00 117.79 ? 100 GLY L CA  1 
ATOM 1706 C C   . GLY B 2 100 ? 274.307 354.450 484.555 1.00 117.79 ? 100 GLY L C   1 
ATOM 1707 O O   . GLY B 2 100 ? 274.303 355.677 484.636 1.00 117.79 ? 100 GLY L O   1 
ATOM 1708 N N   . ALA B 2 101 ? 273.815 353.665 485.512 1.00 122.09 ? 101 ALA L N   1 
ATOM 1709 C CA  . ALA B 2 101 ? 273.306 354.248 486.747 1.00 122.09 ? 101 ALA L CA  1 
ATOM 1710 C C   . ALA B 2 101 ? 274.447 354.751 487.619 1.00 122.09 ? 101 ALA L C   1 
ATOM 1711 O O   . ALA B 2 101 ? 274.446 355.904 488.059 1.00 122.09 ? 101 ALA L O   1 
ATOM 1712 N N   . GLY B 2 102 ? 275.434 353.900 487.872 1.00 125.74 ? 102 GLY L N   1 
ATOM 1713 C CA  . GLY B 2 102 ? 276.569 354.288 488.679 1.00 125.74 ? 102 GLY L CA  1 
ATOM 1714 C C   . GLY B 2 102 ? 276.807 353.355 489.844 1.00 125.74 ? 102 GLY L C   1 
ATOM 1715 O O   . GLY B 2 102 ? 275.878 353.024 490.584 1.00 125.74 ? 102 GLY L O   1 
ATOM 1716 N N   . THR B 2 103 ? 278.051 352.926 490.017 1.00 131.38 ? 103 THR L N   1 
ATOM 1717 C CA  . THR B 2 103 ? 278.448 352.064 491.124 1.00 131.38 ? 103 THR L CA  1 
ATOM 1718 C C   . THR B 2 103 ? 279.381 352.863 492.019 1.00 131.38 ? 103 THR L C   1 
ATOM 1719 O O   . THR B 2 103 ? 280.437 353.317 491.571 1.00 131.38 ? 103 THR L O   1 
ATOM 1720 C CB  . THR B 2 103 ? 279.129 350.794 490.621 1.00 131.38 ? 103 THR L CB  1 
ATOM 1721 O OG1 . THR B 2 103 ? 278.162 349.955 489.983 1.00 131.38 ? 103 THR L OG1 1 
ATOM 1722 C CG2 . THR B 2 103 ? 279.758 350.040 491.771 1.00 131.38 ? 103 THR L CG2 1 
ATOM 1723 N N   . LYS B 2 104 ? 278.986 353.049 493.272 1.00 136.42 ? 104 LYS L N   1 
ATOM 1724 C CA  . LYS B 2 104 ? 279.779 353.814 494.221 1.00 136.42 ? 104 LYS L CA  1 
ATOM 1725 C C   . LYS B 2 104 ? 280.637 352.861 495.040 1.00 136.42 ? 104 LYS L C   1 
ATOM 1726 O O   . LYS B 2 104 ? 280.152 351.826 495.505 1.00 136.42 ? 104 LYS L O   1 
ATOM 1727 C CB  . LYS B 2 104 ? 278.878 354.648 495.127 1.00 136.42 ? 104 LYS L CB  1 
ATOM 1728 C CG  . LYS B 2 104 ? 279.637 355.634 495.980 1.00 136.42 ? 104 LYS L CG  1 
ATOM 1729 C CD  . LYS B 2 104 ? 278.719 356.693 496.544 1.00 136.42 ? 104 LYS L CD  1 
ATOM 1730 C CE  . LYS B 2 104 ? 279.495 357.692 497.380 1.00 136.42 ? 104 LYS L CE  1 
ATOM 1731 N NZ  . LYS B 2 104 ? 278.607 358.716 497.989 1.00 136.42 ? 104 LYS L NZ  1 
ATOM 1732 N N   . LEU B 2 105 ? 281.910 353.202 495.201 1.00 140.30 ? 105 LEU L N   1 
ATOM 1733 C CA  . LEU B 2 105 ? 282.841 352.382 495.964 1.00 140.30 ? 105 LEU L CA  1 
ATOM 1734 C C   . LEU B 2 105 ? 283.273 353.151 497.205 1.00 140.30 ? 105 LEU L C   1 
ATOM 1735 O O   . LEU B 2 105 ? 284.008 354.136 497.106 1.00 140.30 ? 105 LEU L O   1 
ATOM 1736 C CB  . LEU B 2 105 ? 284.045 352.004 495.110 1.00 140.30 ? 105 LEU L CB  1 
ATOM 1737 C CG  . LEU B 2 105 ? 285.016 351.017 495.749 1.00 140.30 ? 105 LEU L CG  1 
ATOM 1738 C CD1 . LEU B 2 105 ? 284.298 349.736 496.099 1.00 140.30 ? 105 LEU L CD1 1 
ATOM 1739 C CD2 . LEU B 2 105 ? 286.166 350.738 494.815 1.00 140.30 ? 105 LEU L CD2 1 
ATOM 1740 N N   . GLU B 2 106 ? 282.817 352.707 498.371 1.00 153.37 ? 106 GLU L N   1 
ATOM 1741 C CA  . GLU B 2 106 ? 283.187 353.318 499.642 1.00 153.37 ? 106 GLU L CA  1 
ATOM 1742 C C   . GLU B 2 106 ? 284.206 352.434 500.349 1.00 153.37 ? 106 GLU L C   1 
ATOM 1743 O O   . GLU B 2 106 ? 284.017 351.218 500.450 1.00 153.37 ? 106 GLU L O   1 
ATOM 1744 C CB  . GLU B 2 106 ? 281.956 353.542 500.525 1.00 153.37 ? 106 GLU L CB  1 
ATOM 1745 C CG  . GLU B 2 106 ? 282.210 353.669 502.050 1.00 153.37 ? 106 GLU L CG  1 
ATOM 1746 C CD  . GLU B 2 106 ? 282.972 354.925 502.517 1.00 153.37 ? 106 GLU L CD  1 
ATOM 1747 O OE1 . GLU B 2 106 ? 283.450 355.746 501.703 1.00 153.37 ? 106 GLU L OE1 1 
ATOM 1748 O OE2 . GLU B 2 106 ? 283.092 355.093 503.748 1.00 153.37 ? 106 GLU L OE2 1 
ATOM 1749 N N   . LEU B 2 107 ? 285.279 353.047 500.837 1.00 156.51 ? 107 LEU L N   1 
ATOM 1750 C CA  . LEU B 2 107 ? 286.338 352.314 501.509 1.00 156.51 ? 107 LEU L CA  1 
ATOM 1751 C C   . LEU B 2 107 ? 285.890 351.858 502.888 1.00 156.51 ? 107 LEU L C   1 
ATOM 1752 O O   . LEU B 2 107 ? 284.970 352.429 503.479 1.00 156.51 ? 107 LEU L O   1 
ATOM 1753 C CB  . LEU B 2 107 ? 287.579 353.190 501.637 1.00 156.51 ? 107 LEU L CB  1 
ATOM 1754 C CG  . LEU B 2 107 ? 288.512 353.212 500.432 1.00 156.51 ? 107 LEU L CG  1 
ATOM 1755 C CD1 . LEU B 2 107 ? 289.789 353.930 500.804 1.00 156.51 ? 107 LEU L CD1 1 
ATOM 1756 C CD2 . LEU B 2 107 ? 288.805 351.804 499.958 1.00 156.51 ? 107 LEU L CD2 1 
ATOM 1757 N N   . LYS B 2 108 ? 286.549 350.827 503.400 1.00 156.23 ? 108 LYS L N   1 
ATOM 1758 C CA  . LYS B 2 108 ? 286.214 350.293 504.712 1.00 156.23 ? 108 LYS L CA  1 
ATOM 1759 C C   . LYS B 2 108 ? 287.337 350.549 505.711 1.00 156.23 ? 108 LYS L C   1 
ATOM 1760 O O   . LYS B 2 108 ? 288.327 349.820 505.746 1.00 156.23 ? 108 LYS L O   1 
ATOM 1761 C CB  . LYS B 2 108 ? 285.920 348.797 504.620 1.00 156.23 ? 108 LYS L CB  1 
ATOM 1762 C CG  . LYS B 2 108 ? 285.408 348.187 505.909 1.00 156.23 ? 108 LYS L CG  1 
ATOM 1763 C CD  . LYS B 2 108 ? 284.772 346.835 505.660 1.00 156.23 ? 108 LYS L CD  1 
ATOM 1764 C CE  . LYS B 2 108 ? 283.563 346.962 504.752 1.00 156.23 ? 108 LYS L CE  1 
ATOM 1765 N NZ  . LYS B 2 108 ? 282.977 345.637 504.417 1.00 156.23 ? 108 LYS L NZ  1 
ATOM 1766 N N   . SER C 3 58  ? 281.828 322.578 433.083 1.00 110.62 ? 58  SER A N   1 
ATOM 1767 C CA  . SER C 3 58  ? 280.557 322.678 433.778 1.00 110.62 ? 58  SER A CA  1 
ATOM 1768 C C   . SER C 3 58  ? 280.276 324.122 434.120 1.00 110.62 ? 58  SER A C   1 
ATOM 1769 O O   . SER C 3 58  ? 280.195 324.499 435.284 1.00 110.62 ? 58  SER A O   1 
ATOM 1770 C CB  . SER C 3 58  ? 280.564 321.821 435.035 1.00 110.62 ? 58  SER A CB  1 
ATOM 1771 O OG  . SER C 3 58  ? 279.535 322.228 435.914 1.00 110.62 ? 58  SER A OG  1 
ATOM 1772 N N   . ARG C 3 59  ? 280.117 324.929 433.081 1.00 110.10 ? 59  ARG A N   1 
ATOM 1773 C CA  . ARG C 3 59  ? 280.100 326.377 433.211 1.00 110.10 ? 59  ARG A CA  1 
ATOM 1774 C C   . ARG C 3 59  ? 278.761 326.971 432.807 1.00 110.10 ? 59  ARG A C   1 
ATOM 1775 O O   . ARG C 3 59  ? 278.667 328.184 432.600 1.00 110.10 ? 59  ARG A O   1 
ATOM 1776 C CB  . ARG C 3 59  ? 281.244 326.936 432.366 1.00 110.10 ? 59  ARG A CB  1 
ATOM 1777 C CG  . ARG C 3 59  ? 281.377 328.447 432.544 1.00 110.10 ? 59  ARG A CG  1 
ATOM 1778 C CD  . ARG C 3 59  ? 282.565 329.059 431.802 1.00 110.10 ? 59  ARG A CD  1 
ATOM 1779 N NE  . ARG C 3 59  ? 282.627 330.511 431.991 1.00 110.10 ? 59  ARG A NE  1 
ATOM 1780 C CZ  . ARG C 3 59  ? 283.173 331.113 433.046 1.00 110.10 ? 59  ARG A CZ  1 
ATOM 1781 N NH1 . ARG C 3 59  ? 283.686 330.401 434.035 1.00 110.10 ? 59  ARG A NH1 1 
ATOM 1782 N NH2 . ARG C 3 59  ? 283.182 332.436 433.125 1.00 110.10 ? 59  ARG A NH2 1 
ATOM 1783 N N   . SER C 3 60  ? 277.722 326.144 432.701 1.00 106.07 ? 60  SER A N   1 
ATOM 1784 C CA  . SER C 3 60  ? 276.457 326.560 432.121 1.00 106.07 ? 60  SER A CA  1 
ATOM 1785 C C   . SER C 3 60  ? 275.343 326.782 433.126 1.00 106.07 ? 60  SER A C   1 
ATOM 1786 O O   . SER C 3 60  ? 274.325 327.380 432.769 1.00 106.07 ? 60  SER A O   1 
ATOM 1787 C CB  . SER C 3 60  ? 275.993 325.519 431.109 1.00 106.07 ? 60  SER A CB  1 
ATOM 1788 O OG  . SER C 3 60  ? 275.327 324.458 431.762 1.00 106.07 ? 60  SER A OG  1 
ATOM 1789 N N   . GLU C 3 61  ? 275.491 326.316 434.359 1.00 104.97 ? 61  GLU A N   1 
ATOM 1790 C CA  . GLU C 3 61  ? 274.466 326.589 435.355 1.00 104.97 ? 61  GLU A CA  1 
ATOM 1791 C C   . GLU C 3 61  ? 274.570 328.013 435.895 1.00 104.97 ? 61  GLU A C   1 
ATOM 1792 O O   . GLU C 3 61  ? 273.636 328.504 436.534 1.00 104.97 ? 61  GLU A O   1 
ATOM 1793 C CB  . GLU C 3 61  ? 274.552 325.538 436.473 1.00 104.97 ? 61  GLU A CB  1 
ATOM 1794 C CG  . GLU C 3 61  ? 273.367 325.504 437.438 1.00 104.97 ? 61  GLU A CG  1 
ATOM 1795 C CD  . GLU C 3 61  ? 273.213 324.188 438.170 1.00 104.97 ? 61  GLU A CD  1 
ATOM 1796 O OE1 . GLU C 3 61  ? 274.234 323.580 438.538 1.00 104.97 ? 61  GLU A OE1 1 
ATOM 1797 O OE2 . GLU C 3 61  ? 272.058 323.764 438.387 1.00 104.97 ? 61  GLU A OE2 1 
ATOM 1798 N N   . SER C 3 62  ? 275.659 328.715 435.602 1.00 96.95  ? 62  SER A N   1 
ATOM 1799 C CA  . SER C 3 62  ? 275.803 330.115 435.956 1.00 96.95  ? 62  SER A CA  1 
ATOM 1800 C C   . SER C 3 62  ? 275.281 331.051 434.879 1.00 96.95  ? 62  SER A C   1 
ATOM 1801 O O   . SER C 3 62  ? 275.509 332.257 434.967 1.00 96.95  ? 62  SER A O   1 
ATOM 1802 C CB  . SER C 3 62  ? 277.264 330.428 436.245 1.00 96.95  ? 62  SER A CB  1 
ATOM 1803 O OG  . SER C 3 62  ? 278.095 329.861 435.252 1.00 96.95  ? 62  SER A OG  1 
ATOM 1804 N N   . SER C 3 63  ? 274.608 330.533 433.859 1.00 93.30  ? 63  SER A N   1 
ATOM 1805 C CA  . SER C 3 63  ? 274.009 331.402 432.860 1.00 93.30  ? 63  SER A CA  1 
ATOM 1806 C C   . SER C 3 63  ? 272.793 332.109 433.441 1.00 93.30  ? 63  SER A C   1 
ATOM 1807 O O   . SER C 3 63  ? 272.211 331.669 434.429 1.00 93.30  ? 63  SER A O   1 
ATOM 1808 C CB  . SER C 3 63  ? 273.601 330.608 431.629 1.00 93.30  ? 63  SER A CB  1 
ATOM 1809 O OG  . SER C 3 63  ? 272.602 331.301 430.911 1.00 93.30  ? 63  SER A OG  1 
ATOM 1810 N N   . ILE C 3 64  ? 272.403 333.217 432.806 1.00 91.79  ? 64  ILE A N   1 
ATOM 1811 C CA  . ILE C 3 64  ? 271.296 334.019 433.322 1.00 91.79  ? 64  ILE A CA  1 
ATOM 1812 C C   . ILE C 3 64  ? 269.971 333.296 433.139 1.00 91.79  ? 64  ILE A C   1 
ATOM 1813 O O   . ILE C 3 64  ? 269.064 333.423 433.970 1.00 91.79  ? 64  ILE A O   1 
ATOM 1814 C CB  . ILE C 3 64  ? 271.298 335.403 432.653 1.00 91.79  ? 64  ILE A CB  1 
ATOM 1815 C CG1 . ILE C 3 64  ? 272.652 336.059 432.850 1.00 91.79  ? 64  ILE A CG1 1 
ATOM 1816 C CG2 . ILE C 3 64  ? 270.262 336.312 433.257 1.00 91.79  ? 64  ILE A CG2 1 
ATOM 1817 C CD1 . ILE C 3 64  ? 273.004 336.270 434.301 1.00 91.79  ? 64  ILE A CD1 1 
ATOM 1818 N N   . GLU C 3 65  ? 269.848 332.492 432.087 1.00 98.69  ? 65  GLU A N   1 
ATOM 1819 C CA  . GLU C 3 65  ? 268.622 331.735 431.875 1.00 98.69  ? 65  GLU A CA  1 
ATOM 1820 C C   . GLU C 3 65  ? 268.449 330.641 432.924 1.00 98.69  ? 65  GLU A C   1 
ATOM 1821 O O   . GLU C 3 65  ? 267.320 330.286 433.270 1.00 98.69  ? 65  GLU A O   1 
ATOM 1822 C CB  . GLU C 3 65  ? 268.619 331.142 430.468 1.00 98.69  ? 65  GLU A CB  1 
ATOM 1823 C CG  . GLU C 3 65  ? 267.309 330.510 429.964 1.00 98.69  ? 65  GLU A CG  1 
ATOM 1824 C CD  . GLU C 3 65  ? 266.065 331.382 430.108 1.00 98.69  ? 65  GLU A CD  1 
ATOM 1825 O OE1 . GLU C 3 65  ? 265.488 331.473 431.213 1.00 98.69  ? 65  GLU A OE1 1 
ATOM 1826 O OE2 . GLU C 3 65  ? 265.655 331.980 429.092 1.00 98.69  ? 65  GLU A OE2 1 
ATOM 1827 N N   . ASN C 3 66  ? 269.543 330.107 433.453 1.00 96.91  ? 66  ASN A N   1 
ATOM 1828 C CA  . ASN C 3 66  ? 269.448 329.081 434.481 1.00 96.91  ? 66  ASN A CA  1 
ATOM 1829 C C   . ASN C 3 66  ? 269.607 329.628 435.888 1.00 96.91  ? 66  ASN A C   1 
ATOM 1830 O O   . ASN C 3 66  ? 269.582 328.848 436.841 1.00 96.91  ? 66  ASN A O   1 
ATOM 1831 C CB  . ASN C 3 66  ? 270.500 328.000 434.255 1.00 96.91  ? 66  ASN A CB  1 
ATOM 1832 C CG  . ASN C 3 66  ? 270.437 327.417 432.873 1.00 96.91  ? 66  ASN A CG  1 
ATOM 1833 O OD1 . ASN C 3 66  ? 269.557 326.618 432.566 1.00 96.91  ? 66  ASN A OD1 1 
ATOM 1834 N ND2 . ASN C 3 66  ? 271.377 327.804 432.026 1.00 96.91  ? 66  ASN A ND2 1 
ATOM 1835 N N   . PHE C 3 67  ? 269.777 330.936 436.042 1.00 87.96  ? 67  PHE A N   1 
ATOM 1836 C CA  . PHE C 3 67  ? 269.940 331.542 437.353 1.00 87.96  ? 67  PHE A CA  1 
ATOM 1837 C C   . PHE C 3 67  ? 268.681 332.221 437.853 1.00 87.96  ? 67  PHE A C   1 
ATOM 1838 O O   . PHE C 3 67  ? 268.434 332.232 439.060 1.00 87.96  ? 67  PHE A O   1 
ATOM 1839 C CB  . PHE C 3 67  ? 271.073 332.566 437.316 1.00 87.96  ? 67  PHE A CB  1 
ATOM 1840 C CG  . PHE C 3 67  ? 271.329 333.236 438.619 1.00 87.96  ? 67  PHE A CG  1 
ATOM 1841 C CD1 . PHE C 3 67  ? 271.807 332.524 439.693 1.00 87.96  ? 67  PHE A CD1 1 
ATOM 1842 C CD2 . PHE C 3 67  ? 271.096 334.586 438.767 1.00 87.96  ? 67  PHE A CD2 1 
ATOM 1843 C CE1 . PHE C 3 67  ? 272.050 333.148 440.893 1.00 87.96  ? 67  PHE A CE1 1 
ATOM 1844 C CE2 . PHE C 3 67  ? 271.333 335.211 439.963 1.00 87.96  ? 67  PHE A CE2 1 
ATOM 1845 C CZ  . PHE C 3 67  ? 271.811 334.491 441.026 1.00 87.96  ? 67  PHE A CZ  1 
ATOM 1846 N N   . LEU C 3 68  ? 267.871 332.777 436.957 1.00 89.22  ? 68  LEU A N   1 
ATOM 1847 C CA  . LEU C 3 68  ? 266.670 333.491 437.348 1.00 89.22  ? 68  LEU A CA  1 
ATOM 1848 C C   . LEU C 3 68  ? 265.374 332.788 436.989 1.00 89.22  ? 68  LEU A C   1 
ATOM 1849 O O   . LEU C 3 68  ? 264.351 333.078 437.614 1.00 89.22  ? 68  LEU A O   1 
ATOM 1850 C CB  . LEU C 3 68  ? 266.652 334.887 436.714 1.00 89.22  ? 68  LEU A CB  1 
ATOM 1851 C CG  . LEU C 3 68  ? 267.739 335.811 437.231 1.00 89.22  ? 68  LEU A CG  1 
ATOM 1852 C CD1 . LEU C 3 68  ? 267.695 337.125 436.507 1.00 89.22  ? 68  LEU A CD1 1 
ATOM 1853 C CD2 . LEU C 3 68  ? 267.527 336.017 438.698 1.00 89.22  ? 68  LEU A CD2 1 
ATOM 1854 N N   . CYS C 3 69  ? 265.377 331.877 436.019 1.00 95.88  ? 69  CYS A N   1 
ATOM 1855 C CA  . CYS C 3 69  ? 264.153 331.180 435.633 1.00 95.88  ? 69  CYS A CA  1 
ATOM 1856 C C   . CYS C 3 69  ? 263.935 330.032 436.614 1.00 95.88  ? 69  CYS A C   1 
ATOM 1857 O O   . CYS C 3 69  ? 264.273 328.874 436.369 1.00 95.88  ? 69  CYS A O   1 
ATOM 1858 C CB  . CYS C 3 69  ? 264.238 330.709 434.189 1.00 95.88  ? 69  CYS A CB  1 
ATOM 1859 S SG  . CYS C 3 69  ? 262.891 329.653 433.615 1.00 95.88  ? 69  CYS A SG  1 
ATOM 1860 N N   . ARG C 3 70  ? 263.397 330.384 437.777 1.00 89.75  ? 70  ARG A N   1 
ATOM 1861 C CA  . ARG C 3 70  ? 263.007 329.435 438.806 1.00 89.75  ? 70  ARG A CA  1 
ATOM 1862 C C   . ARG C 3 70  ? 261.616 329.804 439.300 1.00 89.75  ? 70  ARG A C   1 
ATOM 1863 O O   . ARG C 3 70  ? 261.111 330.893 439.029 1.00 89.75  ? 70  ARG A O   1 
ATOM 1864 C CB  . ARG C 3 70  ? 263.994 329.427 439.980 1.00 89.75  ? 70  ARG A CB  1 
ATOM 1865 C CG  . ARG C 3 70  ? 265.444 329.194 439.613 1.00 89.75  ? 70  ARG A CG  1 
ATOM 1866 C CD  . ARG C 3 70  ? 265.761 327.728 439.527 1.00 89.75  ? 70  ARG A CD  1 
ATOM 1867 N NE  . ARG C 3 70  ? 267.118 327.511 439.048 1.00 89.75  ? 70  ARG A NE  1 
ATOM 1868 C CZ  . ARG C 3 70  ? 267.760 326.355 439.137 1.00 89.75  ? 70  ARG A CZ  1 
ATOM 1869 N NH1 . ARG C 3 70  ? 267.166 325.310 439.690 1.00 89.75  ? 70  ARG A NH1 1 
ATOM 1870 N NH2 . ARG C 3 70  ? 268.995 326.243 438.676 1.00 89.75  ? 70  ARG A NH2 1 
ATOM 1871 N N   . SER C 3 71  ? 261.000 328.899 440.048 1.00 86.76  ? 71  SER A N   1 
ATOM 1872 C CA  . SER C 3 71  ? 259.669 329.119 440.590 1.00 86.76  ? 71  SER A CA  1 
ATOM 1873 C C   . SER C 3 71  ? 259.761 329.417 442.076 1.00 86.76  ? 71  SER A C   1 
ATOM 1874 O O   . SER C 3 71  ? 260.519 328.768 442.800 1.00 86.76  ? 71  SER A O   1 
ATOM 1875 C CB  . SER C 3 71  ? 258.779 327.904 440.359 1.00 86.76  ? 71  SER A CB  1 
ATOM 1876 O OG  . SER C 3 71  ? 258.554 327.707 438.978 1.00 86.76  ? 71  SER A OG  1 
ATOM 1877 N N   . ALA C 3 72  ? 258.985 330.394 442.535 1.00 82.64  ? 72  ALA A N   1 
ATOM 1878 C CA  . ALA C 3 72  ? 259.054 330.832 443.918 1.00 82.64  ? 72  ALA A CA  1 
ATOM 1879 C C   . ALA C 3 72  ? 257.684 331.276 444.395 1.00 82.64  ? 72  ALA A C   1 
ATOM 1880 O O   . ALA C 3 72  ? 256.985 332.001 443.688 1.00 82.64  ? 72  ALA A O   1 
ATOM 1881 C CB  . ALA C 3 72  ? 260.047 331.979 444.078 1.00 82.64  ? 72  ALA A CB  1 
ATOM 1882 N N   . CYS C 3 73  ? 257.308 330.852 445.597 1.00 84.06  ? 73  CYS A N   1 
ATOM 1883 C CA  . CYS C 3 73  ? 256.044 331.271 446.194 1.00 84.06  ? 73  CYS A CA  1 
ATOM 1884 C C   . CYS C 3 73  ? 256.180 332.709 446.659 1.00 84.06  ? 73  CYS A C   1 
ATOM 1885 O O   . CYS C 3 73  ? 257.055 333.022 447.468 1.00 84.06  ? 73  CYS A O   1 
ATOM 1886 C CB  . CYS C 3 73  ? 255.667 330.367 447.360 1.00 84.06  ? 73  CYS A CB  1 
ATOM 1887 S SG  . CYS C 3 73  ? 254.399 331.072 448.425 1.00 84.06  ? 73  CYS A SG  1 
ATOM 1888 N N   . VAL C 3 74  ? 255.319 333.589 446.156 1.00 79.04  ? 74  VAL A N   1 
ATOM 1889 C CA  . VAL C 3 74  ? 255.447 335.008 446.457 1.00 79.04  ? 74  VAL A CA  1 
ATOM 1890 C C   . VAL C 3 74  ? 254.272 335.519 447.276 1.00 79.04  ? 74  VAL A C   1 
ATOM 1891 O O   . VAL C 3 74  ? 254.406 336.498 448.013 1.00 79.04  ? 74  VAL A O   1 
ATOM 1892 C CB  . VAL C 3 74  ? 255.616 335.826 445.169 1.00 79.04  ? 74  VAL A CB  1 
ATOM 1893 C CG1 . VAL C 3 74  ? 256.945 335.532 444.549 1.00 79.04  ? 74  VAL A CG1 1 
ATOM 1894 C CG2 . VAL C 3 74  ? 254.548 335.472 444.197 1.00 79.04  ? 74  VAL A CG2 1 
ATOM 1895 N N   . TYR C 3 75  ? 253.118 334.872 447.177 1.00 83.33  ? 75  TYR A N   1 
ATOM 1896 C CA  . TYR C 3 75  ? 251.947 335.362 447.882 1.00 83.33  ? 75  TYR A CA  1 
ATOM 1897 C C   . TYR C 3 75  ? 251.157 334.201 448.454 1.00 83.33  ? 75  TYR A C   1 
ATOM 1898 O O   . TYR C 3 75  ? 251.202 333.087 447.934 1.00 83.33  ? 75  TYR A O   1 
ATOM 1899 C CB  . TYR C 3 75  ? 251.049 336.184 446.973 1.00 83.33  ? 75  TYR A CB  1 
ATOM 1900 C CG  . TYR C 3 75  ? 250.168 337.134 447.725 1.00 83.33  ? 75  TYR A CG  1 
ATOM 1901 C CD1 . TYR C 3 75  ? 250.689 337.944 448.719 1.00 83.33  ? 75  TYR A CD1 1 
ATOM 1902 C CD2 . TYR C 3 75  ? 248.817 337.219 447.449 1.00 83.33  ? 75  TYR A CD2 1 
ATOM 1903 C CE1 . TYR C 3 75  ? 249.888 338.815 449.415 1.00 83.33  ? 75  TYR A CE1 1 
ATOM 1904 C CE2 . TYR C 3 75  ? 248.011 338.085 448.137 1.00 83.33  ? 75  TYR A CE2 1 
ATOM 1905 C CZ  . TYR C 3 75  ? 248.549 338.880 449.121 1.00 83.33  ? 75  TYR A CZ  1 
ATOM 1906 O OH  . TYR C 3 75  ? 247.742 339.747 449.814 1.00 83.33  ? 75  TYR A OH  1 
ATOM 1907 N N   . TYR C 3 76  ? 250.422 334.479 449.526 1.00 90.13  ? 76  TYR A N   1 
ATOM 1908 C CA  . TYR C 3 76  ? 249.613 333.455 450.175 1.00 90.13  ? 76  TYR A CA  1 
ATOM 1909 C C   . TYR C 3 76  ? 248.489 334.164 450.919 1.00 90.13  ? 76  TYR A C   1 
ATOM 1910 O O   . TYR C 3 76  ? 248.740 334.806 451.941 1.00 90.13  ? 76  TYR A O   1 
ATOM 1911 C CB  . TYR C 3 76  ? 250.464 332.616 451.113 1.00 90.13  ? 76  TYR A CB  1 
ATOM 1912 C CG  . TYR C 3 76  ? 249.673 331.846 452.127 1.00 90.13  ? 76  TYR A CG  1 
ATOM 1913 C CD1 . TYR C 3 76  ? 248.814 330.836 451.738 1.00 90.13  ? 76  TYR A CD1 1 
ATOM 1914 C CD2 . TYR C 3 76  ? 249.786 332.128 453.476 1.00 90.13  ? 76  TYR A CD2 1 
ATOM 1915 C CE1 . TYR C 3 76  ? 248.083 330.130 452.663 1.00 90.13  ? 76  TYR A CE1 1 
ATOM 1916 C CE2 . TYR C 3 76  ? 249.061 331.427 454.410 1.00 90.13  ? 76  TYR A CE2 1 
ATOM 1917 C CZ  . TYR C 3 76  ? 248.210 330.427 453.997 1.00 90.13  ? 76  TYR A CZ  1 
ATOM 1918 O OH  . TYR C 3 76  ? 247.482 329.723 454.925 1.00 90.13  ? 76  TYR A OH  1 
ATOM 1919 N N   . ALA C 3 77  ? 247.265 334.055 450.411 1.00 87.94  ? 77  ALA A N   1 
ATOM 1920 C CA  . ALA C 3 77  ? 246.144 334.805 450.952 1.00 87.94  ? 77  ALA A CA  1 
ATOM 1921 C C   . ALA C 3 77  ? 244.920 333.915 451.058 1.00 87.94  ? 77  ALA A C   1 
ATOM 1922 O O   . ALA C 3 77  ? 244.783 332.926 450.339 1.00 87.94  ? 77  ALA A O   1 
ATOM 1923 C CB  . ALA C 3 77  ? 245.808 336.019 450.089 1.00 87.94  ? 77  ALA A CB  1 
ATOM 1924 N N   . THR C 3 78  ? 244.020 334.288 451.960 1.00 88.79  ? 78  THR A N   1 
ATOM 1925 C CA  . THR C 3 78  ? 242.783 333.559 452.183 1.00 88.79  ? 78  THR A CA  1 
ATOM 1926 C C   . THR C 3 78  ? 241.596 334.437 451.829 1.00 88.79  ? 78  THR A C   1 
ATOM 1927 O O   . THR C 3 78  ? 241.661 335.662 451.931 1.00 88.79  ? 78  THR A O   1 
ATOM 1928 C CB  . THR C 3 78  ? 242.639 333.121 453.634 1.00 88.79  ? 78  THR A CB  1 
ATOM 1929 O OG1 . THR C 3 78  ? 242.511 334.278 454.461 1.00 88.79  ? 78  THR A OG1 1 
ATOM 1930 C CG2 . THR C 3 78  ? 243.854 332.350 454.075 1.00 88.79  ? 78  THR A CG2 1 
ATOM 1931 N N   . TYR C 3 79  ? 240.503 333.797 451.432 1.00 85.27  ? 79  TYR A N   1 
ATOM 1932 C CA  . TYR C 3 79  ? 239.258 334.506 451.191 1.00 85.27  ? 79  TYR A CA  1 
ATOM 1933 C C   . TYR C 3 79  ? 238.106 333.537 451.373 1.00 85.27  ? 79  TYR A C   1 
ATOM 1934 O O   . TYR C 3 79  ? 238.171 332.399 450.912 1.00 85.27  ? 79  TYR A O   1 
ATOM 1935 C CB  . TYR C 3 79  ? 239.215 335.134 449.795 1.00 85.27  ? 79  TYR A CB  1 
ATOM 1936 C CG  . TYR C 3 79  ? 239.421 334.187 448.642 1.00 85.27  ? 79  TYR A CG  1 
ATOM 1937 C CD1 . TYR C 3 79  ? 240.689 333.885 448.190 1.00 85.27  ? 79  TYR A CD1 1 
ATOM 1938 C CD2 . TYR C 3 79  ? 238.347 333.632 447.979 1.00 85.27  ? 79  TYR A CD2 1 
ATOM 1939 C CE1 . TYR C 3 79  ? 240.879 333.035 447.131 1.00 85.27  ? 79  TYR A CE1 1 
ATOM 1940 C CE2 . TYR C 3 79  ? 238.531 332.781 446.922 1.00 85.27  ? 79  TYR A CE2 1 
ATOM 1941 C CZ  . TYR C 3 79  ? 239.797 332.487 446.505 1.00 85.27  ? 79  TYR A CZ  1 
ATOM 1942 O OH  . TYR C 3 79  ? 239.977 331.638 445.448 1.00 85.27  ? 79  TYR A OH  1 
ATOM 1943 N N   . THR C 3 80  ? 237.066 333.989 452.051 1.00 94.32  ? 80  THR A N   1 
ATOM 1944 C CA  . THR C 3 80  ? 235.861 333.207 452.242 1.00 94.32  ? 80  THR A CA  1 
ATOM 1945 C C   . THR C 3 80  ? 234.784 333.731 451.309 1.00 94.32  ? 80  THR A C   1 
ATOM 1946 O O   . THR C 3 80  ? 234.957 334.755 450.647 1.00 94.32  ? 80  THR A O   1 
ATOM 1947 C CB  . THR C 3 80  ? 235.395 333.262 453.694 1.00 94.32  ? 80  THR A CB  1 
ATOM 1948 O OG1 . THR C 3 80  ? 234.112 332.641 453.806 1.00 94.32  ? 80  THR A OG1 1 
ATOM 1949 C CG2 . THR C 3 80  ? 235.309 334.684 454.154 1.00 94.32  ? 80  THR A CG2 1 
ATOM 1950 N N   . ASN C 3 81  ? 233.660 333.024 451.246 1.00 98.97  ? 81  ASN A N   1 
ATOM 1951 C CA  . ASN C 3 81  ? 232.680 333.367 450.224 1.00 98.97  ? 81  ASN A CA  1 
ATOM 1952 C C   . ASN C 3 81  ? 231.533 334.217 450.749 1.00 98.97  ? 81  ASN A C   1 
ATOM 1953 O O   . ASN C 3 81  ? 231.062 335.112 450.043 1.00 98.97  ? 81  ASN A O   1 
ATOM 1954 C CB  . ASN C 3 81  ? 232.120 332.102 449.581 1.00 98.97  ? 81  ASN A CB  1 
ATOM 1955 C CG  . ASN C 3 81  ? 231.625 331.117 450.590 1.00 98.97  ? 81  ASN A CG  1 
ATOM 1956 O OD1 . ASN C 3 81  ? 231.837 331.286 451.785 1.00 98.97  ? 81  ASN A OD1 1 
ATOM 1957 N ND2 . ASN C 3 81  ? 230.958 330.076 450.121 1.00 98.97  ? 81  ASN A ND2 1 
ATOM 1958 N N   . ASN C 3 82  ? 231.066 333.966 451.968 1.00 107.96 ? 82  ASN A N   1 
ATOM 1959 C CA  . ASN C 3 82  ? 229.820 334.582 452.402 1.00 107.96 ? 82  ASN A CA  1 
ATOM 1960 C C   . ASN C 3 82  ? 230.011 335.880 453.174 1.00 107.96 ? 82  ASN A C   1 
ATOM 1961 O O   . ASN C 3 82  ? 229.023 336.569 453.438 1.00 107.96 ? 82  ASN A O   1 
ATOM 1962 C CB  . ASN C 3 82  ? 229.023 333.599 453.257 1.00 107.96 ? 82  ASN A CB  1 
ATOM 1963 C CG  . ASN C 3 82  ? 229.600 333.436 454.638 1.00 107.96 ? 82  ASN A CG  1 
ATOM 1964 O OD1 . ASN C 3 82  ? 230.814 333.365 454.813 1.00 107.96 ? 82  ASN A OD1 1 
ATOM 1965 N ND2 . ASN C 3 82  ? 228.730 333.371 455.634 1.00 107.96 ? 82  ASN A ND2 1 
ATOM 1966 N N   . SER C 3 83  ? 231.238 336.241 453.536 1.00 110.80 ? 83  SER A N   1 
ATOM 1967 C CA  . SER C 3 83  ? 231.439 337.341 454.473 1.00 110.80 ? 83  SER A CA  1 
ATOM 1968 C C   . SER C 3 83  ? 231.442 338.715 453.818 1.00 110.80 ? 83  SER A C   1 
ATOM 1969 O O   . SER C 3 83  ? 231.874 339.670 454.470 1.00 110.80 ? 83  SER A O   1 
ATOM 1970 C CB  . SER C 3 83  ? 232.749 337.153 455.234 1.00 110.80 ? 83  SER A CB  1 
ATOM 1971 O OG  . SER C 3 83  ? 233.828 337.749 454.535 1.00 110.80 ? 83  SER A OG  1 
ATOM 1972 N N   . LYS C 3 84  ? 231.062 338.815 452.537 1.00 113.37 ? 84  LYS A N   1 
ATOM 1973 C CA  . LYS C 3 84  ? 230.854 340.031 451.737 1.00 113.37 ? 84  LYS A CA  1 
ATOM 1974 C C   . LYS C 3 84  ? 232.070 340.959 451.617 1.00 113.37 ? 84  LYS A C   1 
ATOM 1975 O O   . LYS C 3 84  ? 231.986 342.019 450.989 1.00 113.37 ? 84  LYS A O   1 
ATOM 1976 C CB  . LYS C 3 84  ? 229.628 340.808 452.258 1.00 113.37 ? 84  LYS A CB  1 
ATOM 1977 C CG  . LYS C 3 84  ? 229.842 341.842 453.368 1.00 113.37 ? 84  LYS A CG  1 
ATOM 1978 C CD  . LYS C 3 84  ? 228.565 342.074 454.157 1.00 113.37 ? 84  LYS A CD  1 
ATOM 1979 C CE  . LYS C 3 84  ? 228.221 340.862 455.004 1.00 113.37 ? 84  LYS A CE  1 
ATOM 1980 N NZ  . LYS C 3 84  ? 229.283 340.576 456.004 1.00 113.37 ? 84  LYS A NZ  1 
ATOM 1981 N N   . LYS C 3 85  ? 233.220 340.544 452.150 1.00 107.89 ? 85  LYS A N   1 
ATOM 1982 C CA  . LYS C 3 85  ? 234.503 341.173 451.876 1.00 107.89 ? 85  LYS A CA  1 
ATOM 1983 C C   . LYS C 3 85  ? 235.594 340.117 451.753 1.00 107.89 ? 85  LYS A C   1 
ATOM 1984 O O   . LYS C 3 85  ? 236.736 340.343 452.164 1.00 107.89 ? 85  LYS A O   1 
ATOM 1985 C CB  . LYS C 3 85  ? 234.862 342.208 452.939 1.00 107.89 ? 85  LYS A CB  1 
ATOM 1986 C CG  . LYS C 3 85  ? 234.585 341.774 454.357 1.00 107.89 ? 85  LYS A CG  1 
ATOM 1987 C CD  . LYS C 3 85  ? 235.119 342.799 455.338 1.00 107.89 ? 85  LYS A CD  1 
ATOM 1988 C CE  . LYS C 3 85  ? 234.922 342.345 456.772 1.00 107.89 ? 85  LYS A CE  1 
ATOM 1989 N NZ  . LYS C 3 85  ? 235.611 343.246 457.734 1.00 107.89 ? 85  LYS A NZ  1 
ATOM 1990 N N   . GLY C 3 86  ? 235.243 338.944 451.240 1.00 92.46  ? 86  GLY A N   1 
ATOM 1991 C CA  . GLY C 3 86  ? 236.222 337.927 450.944 1.00 92.46  ? 86  GLY A CA  1 
ATOM 1992 C C   . GLY C 3 86  ? 236.587 337.889 449.478 1.00 92.46  ? 86  GLY A C   1 
ATOM 1993 O O   . GLY C 3 86  ? 235.860 337.320 448.661 1.00 92.46  ? 86  GLY A O   1 
ATOM 1994 N N   . PHE C 3 87  ? 237.717 338.505 449.145 1.00 87.70  ? 87  PHE A N   1 
ATOM 1995 C CA  . PHE C 3 87  ? 238.334 338.418 447.830 1.00 87.70  ? 87  PHE A CA  1 
ATOM 1996 C C   . PHE C 3 87  ? 239.786 338.834 447.987 1.00 87.70  ? 87  PHE A C   1 
ATOM 1997 O O   . PHE C 3 87  ? 240.105 339.719 448.781 1.00 87.70  ? 87  PHE A O   1 
ATOM 1998 C CB  . PHE C 3 87  ? 237.619 339.286 446.787 1.00 87.70  ? 87  PHE A CB  1 
ATOM 1999 C CG  . PHE C 3 87  ? 237.864 340.753 446.929 1.00 87.70  ? 87  PHE A CG  1 
ATOM 2000 C CD1 . PHE C 3 87  ? 237.240 341.477 447.918 1.00 87.70  ? 87  PHE A CD1 1 
ATOM 2001 C CD2 . PHE C 3 87  ? 238.698 341.409 446.056 1.00 87.70  ? 87  PHE A CD2 1 
ATOM 2002 C CE1 . PHE C 3 87  ? 237.457 342.821 448.045 1.00 87.70  ? 87  PHE A CE1 1 
ATOM 2003 C CE2 . PHE C 3 87  ? 238.920 342.754 446.181 1.00 87.70  ? 87  PHE A CE2 1 
ATOM 2004 C CZ  . PHE C 3 87  ? 238.299 343.459 447.177 1.00 87.70  ? 87  PHE A CZ  1 
ATOM 2005 N N   . ALA C 3 88  ? 240.664 338.175 447.251 1.00 87.46  ? 88  ALA A N   1 
ATOM 2006 C CA  . ALA C 3 88  ? 242.087 338.405 447.422 1.00 87.46  ? 88  ALA A CA  1 
ATOM 2007 C C   . ALA C 3 88  ? 242.539 339.607 446.606 1.00 87.46  ? 88  ALA A C   1 
ATOM 2008 O O   . ALA C 3 88  ? 241.771 340.206 445.859 1.00 87.46  ? 88  ALA A O   1 
ATOM 2009 C CB  . ALA C 3 88  ? 242.879 337.165 447.034 1.00 87.46  ? 88  ALA A CB  1 
ATOM 2010 N N   . GLU C 3 89  ? 243.814 339.950 446.756 1.00 90.16  ? 89  GLU A N   1 
ATOM 2011 C CA  . GLU C 3 89  ? 244.380 341.147 446.150 1.00 90.16  ? 89  GLU A CA  1 
ATOM 2012 C C   . GLU C 3 89  ? 245.890 341.030 446.156 1.00 90.16  ? 89  GLU A C   1 
ATOM 2013 O O   . GLU C 3 89  ? 246.469 340.703 447.191 1.00 90.16  ? 89  GLU A O   1 
ATOM 2014 C CB  . GLU C 3 89  ? 243.967 342.393 446.921 1.00 90.16  ? 89  GLU A CB  1 
ATOM 2015 C CG  . GLU C 3 89  ? 244.279 343.682 446.215 1.00 90.16  ? 89  GLU A CG  1 
ATOM 2016 C CD  . GLU C 3 89  ? 243.261 344.759 446.510 1.00 90.16  ? 89  GLU A CD  1 
ATOM 2017 O OE1 . GLU C 3 89  ? 242.661 344.726 447.605 1.00 90.16  ? 89  GLU A OE1 1 
ATOM 2018 O OE2 . GLU C 3 89  ? 243.062 345.643 445.651 1.00 90.16  ? 89  GLU A OE2 1 
ATOM 2019 N N   . TRP C 3 90  ? 246.526 341.323 445.028 1.00 82.72  ? 90  TRP A N   1 
ATOM 2020 C CA  . TRP C 3 90  ? 247.983 341.342 444.984 1.00 82.72  ? 90  TRP A CA  1 
ATOM 2021 C C   . TRP C 3 90  ? 248.442 342.248 443.858 1.00 82.72  ? 90  TRP A C   1 
ATOM 2022 O O   . TRP C 3 90  ? 248.128 341.988 442.696 1.00 82.72  ? 90  TRP A O   1 
ATOM 2023 C CB  . TRP C 3 90  ? 248.554 339.943 444.791 1.00 82.72  ? 90  TRP A CB  1 
ATOM 2024 C CG  . TRP C 3 90  ? 250.029 339.915 444.901 1.00 82.72  ? 90  TRP A CG  1 
ATOM 2025 C CD1 . TRP C 3 90  ? 250.773 340.437 445.904 1.00 82.72  ? 90  TRP A CD1 1 
ATOM 2026 C CD2 . TRP C 3 90  ? 250.946 339.335 443.980 1.00 82.72  ? 90  TRP A CD2 1 
ATOM 2027 N NE1 . TRP C 3 90  ? 252.103 340.223 445.668 1.00 82.72  ? 90  TRP A NE1 1 
ATOM 2028 C CE2 . TRP C 3 90  ? 252.235 339.547 444.488 1.00 82.72  ? 90  TRP A CE2 1 
ATOM 2029 C CE3 . TRP C 3 90  ? 250.805 338.658 442.773 1.00 82.72  ? 90  TRP A CE3 1 
ATOM 2030 C CZ2 . TRP C 3 90  ? 253.369 339.108 443.835 1.00 82.72  ? 90  TRP A CZ2 1 
ATOM 2031 C CZ3 . TRP C 3 90  ? 251.930 338.224 442.128 1.00 82.72  ? 90  TRP A CZ3 1 
ATOM 2032 C CH2 . TRP C 3 90  ? 253.197 338.450 442.657 1.00 82.72  ? 90  TRP A CH2 1 
ATOM 2033 N N   . VAL C 3 91  ? 249.177 343.298 444.199 1.00 83.00  ? 91  VAL A N   1 
ATOM 2034 C CA  . VAL C 3 91  ? 249.822 344.141 443.200 1.00 83.00  ? 91  VAL A CA  1 
ATOM 2035 C C   . VAL C 3 91  ? 251.131 343.481 442.803 1.00 83.00  ? 91  VAL A C   1 
ATOM 2036 O O   . VAL C 3 91  ? 251.989 343.238 443.654 1.00 83.00  ? 91  VAL A O   1 
ATOM 2037 C CB  . VAL C 3 91  ? 250.068 345.550 443.742 1.00 83.00  ? 91  VAL A CB  1 
ATOM 2038 C CG1 . VAL C 3 91  ? 250.799 346.371 442.717 1.00 83.00  ? 91  VAL A CG1 1 
ATOM 2039 C CG2 . VAL C 3 91  ? 248.760 346.197 444.114 1.00 83.00  ? 91  VAL A CG2 1 
ATOM 2040 N N   . ILE C 3 92  ? 251.291 343.196 441.516 1.00 83.20  ? 92  ILE A N   1 
ATOM 2041 C CA  . ILE C 3 92  ? 252.417 342.397 441.050 1.00 83.20  ? 92  ILE A CA  1 
ATOM 2042 C C   . ILE C 3 92  ? 253.688 343.228 441.117 1.00 83.20  ? 92  ILE A C   1 
ATOM 2043 O O   . ILE C 3 92  ? 253.807 344.257 440.447 1.00 83.20  ? 92  ILE A O   1 
ATOM 2044 C CB  . ILE C 3 92  ? 252.178 341.877 439.630 1.00 83.20  ? 92  ILE A CB  1 
ATOM 2045 C CG1 . ILE C 3 92  ? 251.028 340.884 439.626 1.00 83.20  ? 92  ILE A CG1 1 
ATOM 2046 C CG2 . ILE C 3 92  ? 253.419 341.209 439.108 1.00 83.20  ? 92  ILE A CG2 1 
ATOM 2047 C CD1 . ILE C 3 92  ? 250.737 340.315 438.276 1.00 83.20  ? 92  ILE A CD1 1 
ATOM 2048 N N   . ASN C 3 93  ? 254.636 342.787 441.936 1.00 90.75  ? 93  ASN A N   1 
ATOM 2049 C CA  . ASN C 3 93  ? 255.939 343.422 442.027 1.00 90.75  ? 93  ASN A CA  1 
ATOM 2050 C C   . ASN C 3 93  ? 256.976 342.338 442.269 1.00 90.75  ? 93  ASN A C   1 
ATOM 2051 O O   . ASN C 3 93  ? 256.647 341.162 442.431 1.00 90.75  ? 93  ASN A O   1 
ATOM 2052 C CB  . ASN C 3 93  ? 255.968 344.472 443.131 1.00 90.75  ? 93  ASN A CB  1 
ATOM 2053 C CG  . ASN C 3 93  ? 255.310 343.992 444.396 1.00 90.75  ? 93  ASN A CG  1 
ATOM 2054 O OD1 . ASN C 3 93  ? 254.856 342.857 444.474 1.00 90.75  ? 93  ASN A OD1 1 
ATOM 2055 N ND2 . ASN C 3 93  ? 255.253 344.856 445.397 1.00 90.75  ? 93  ASN A ND2 1 
ATOM 2056 N N   . THR C 3 94  ? 258.239 342.744 442.301 1.00 94.20  ? 94  THR A N   1 
ATOM 2057 C CA  . THR C 3 94  ? 259.327 341.819 442.564 1.00 94.20  ? 94  THR A CA  1 
ATOM 2058 C C   . THR C 3 94  ? 259.848 341.912 443.985 1.00 94.20  ? 94  THR A C   1 
ATOM 2059 O O   . THR C 3 94  ? 260.609 341.040 444.405 1.00 94.20  ? 94  THR A O   1 
ATOM 2060 C CB  . THR C 3 94  ? 260.487 342.073 441.604 1.00 94.20  ? 94  THR A CB  1 
ATOM 2061 O OG1 . THR C 3 94  ? 261.279 343.154 442.104 1.00 94.20  ? 94  THR A OG1 1 
ATOM 2062 C CG2 . THR C 3 94  ? 259.967 342.435 440.234 1.00 94.20  ? 94  THR A CG2 1 
ATOM 2063 N N   . ARG C 3 95  ? 259.443 342.930 444.738 1.00 97.74  ? 95  ARG A N   1 
ATOM 2064 C CA  . ARG C 3 95  ? 259.993 343.200 446.057 1.00 97.74  ? 95  ARG A CA  1 
ATOM 2065 C C   . ARG C 3 95  ? 259.167 342.573 447.167 1.00 97.74  ? 95  ARG A C   1 
ATOM 2066 O O   . ARG C 3 95  ? 259.054 343.146 448.252 1.00 97.74  ? 95  ARG A O   1 
ATOM 2067 C CB  . ARG C 3 95  ? 260.103 344.703 446.277 1.00 97.74  ? 95  ARG A CB  1 
ATOM 2068 C CG  . ARG C 3 95  ? 260.758 345.434 445.139 1.00 97.74  ? 95  ARG A CG  1 
ATOM 2069 C CD  . ARG C 3 95  ? 260.896 346.901 445.450 1.00 97.74  ? 95  ARG A CD  1 
ATOM 2070 N NE  . ARG C 3 95  ? 261.993 347.498 444.703 1.00 97.74  ? 95  ARG A NE  1 
ATOM 2071 C CZ  . ARG C 3 95  ? 262.367 348.765 444.819 1.00 97.74  ? 95  ARG A CZ  1 
ATOM 2072 N NH1 . ARG C 3 95  ? 261.725 349.571 445.651 1.00 97.74  ? 95  ARG A NH1 1 
ATOM 2073 N NH2 . ARG C 3 95  ? 263.380 349.228 444.101 1.00 97.74  ? 95  ARG A NH2 1 
ATOM 2074 N N   . GLN C 3 96  ? 258.577 341.409 446.920 1.00 97.80  ? 96  GLN A N   1 
ATOM 2075 C CA  . GLN C 3 96  ? 257.701 340.827 447.925 1.00 97.80  ? 96  GLN A CA  1 
ATOM 2076 C C   . GLN C 3 96  ? 258.484 339.982 448.919 1.00 97.80  ? 96  GLN A C   1 
ATOM 2077 O O   . GLN C 3 96  ? 258.497 340.270 450.118 1.00 97.80  ? 96  GLN A O   1 
ATOM 2078 C CB  . GLN C 3 96  ? 256.615 339.991 447.257 1.00 97.80  ? 96  GLN A CB  1 
ATOM 2079 C CG  . GLN C 3 96  ? 255.500 339.616 448.192 1.00 97.80  ? 96  GLN A CG  1 
ATOM 2080 C CD  . GLN C 3 96  ? 254.599 340.779 448.495 1.00 97.80  ? 96  GLN A CD  1 
ATOM 2081 O OE1 . GLN C 3 96  ? 254.182 340.973 449.634 1.00 97.80  ? 96  GLN A OE1 1 
ATOM 2082 N NE2 . GLN C 3 96  ? 254.287 341.565 447.476 1.00 97.80  ? 96  GLN A NE2 1 
ATOM 2083 N N   . VAL C 3 97  ? 259.143 338.941 448.442 1.00 94.08  ? 97  VAL A N   1 
ATOM 2084 C CA  . VAL C 3 97  ? 259.863 338.021 449.308 1.00 94.08  ? 97  VAL A CA  1 
ATOM 2085 C C   . VAL C 3 97  ? 261.335 338.405 449.286 1.00 94.08  ? 97  VAL A C   1 
ATOM 2086 O O   . VAL C 3 97  ? 261.815 339.015 448.324 1.00 94.08  ? 97  VAL A O   1 
ATOM 2087 C CB  . VAL C 3 97  ? 259.619 336.559 448.879 1.00 94.08  ? 97  VAL A CB  1 
ATOM 2088 C CG1 . VAL C 3 97  ? 260.424 336.184 447.660 1.00 94.08  ? 97  VAL A CG1 1 
ATOM 2089 C CG2 . VAL C 3 97  ? 259.867 335.596 450.026 1.00 94.08  ? 97  VAL A CG2 1 
ATOM 2090 N N   . ALA C 3 98  ? 262.046 338.108 450.372 1.00 92.32  ? 98  ALA A N   1 
ATOM 2091 C CA  . ALA C 3 98  ? 263.399 338.621 450.516 1.00 92.32  ? 98  ALA A CA  1 
ATOM 2092 C C   . ALA C 3 98  ? 264.420 337.824 449.726 1.00 92.32  ? 98  ALA A C   1 
ATOM 2093 O O   . ALA C 3 98  ? 265.476 338.363 449.395 1.00 92.32  ? 98  ALA A O   1 
ATOM 2094 C CB  . ALA C 3 98  ? 263.802 338.639 451.986 1.00 92.32  ? 98  ALA A CB  1 
ATOM 2095 N N   . GLN C 3 99  ? 264.140 336.565 449.416 1.00 94.55  ? 99  GLN A N   1 
ATOM 2096 C CA  . GLN C 3 99  ? 265.145 335.761 448.734 1.00 94.55  ? 99  GLN A CA  1 
ATOM 2097 C C   . GLN C 3 99  ? 265.168 336.034 447.240 1.00 94.55  ? 99  GLN A C   1 
ATOM 2098 O O   . GLN C 3 99  ? 266.241 336.071 446.635 1.00 94.55  ? 99  GLN A O   1 
ATOM 2099 C CB  . GLN C 3 99  ? 264.897 334.281 448.994 1.00 94.55  ? 99  GLN A CB  1 
ATOM 2100 C CG  . GLN C 3 99  ? 265.549 333.767 450.250 1.00 94.55  ? 99  GLN A CG  1 
ATOM 2101 C CD  . GLN C 3 99  ? 266.986 333.354 450.031 1.00 94.55  ? 99  GLN A CD  1 
ATOM 2102 O OE1 . GLN C 3 99  ? 267.540 333.533 448.948 1.00 94.55  ? 99  GLN A OE1 1 
ATOM 2103 N NE2 . GLN C 3 99  ? 267.598 332.785 451.061 1.00 94.55  ? 99  GLN A NE2 1 
ATOM 2104 N N   . LEU C 3 100 ? 263.999 336.209 446.625 1.00 89.54  ? 100 LEU A N   1 
ATOM 2105 C CA  . LEU C 3 100 ? 263.956 336.503 445.199 1.00 89.54  ? 100 LEU A CA  1 
ATOM 2106 C C   . LEU C 3 100 ? 264.365 337.937 444.918 1.00 89.54  ? 100 LEU A C   1 
ATOM 2107 O O   . LEU C 3 100 ? 264.854 338.237 443.825 1.00 89.54  ? 100 LEU A O   1 
ATOM 2108 C CB  . LEU C 3 100 ? 262.558 336.244 444.651 1.00 89.54  ? 100 LEU A CB  1 
ATOM 2109 C CG  . LEU C 3 100 ? 262.365 336.303 443.140 1.00 89.54  ? 100 LEU A CG  1 
ATOM 2110 C CD1 . LEU C 3 100 ? 263.211 335.249 442.464 1.00 89.54  ? 100 LEU A CD1 1 
ATOM 2111 C CD2 . LEU C 3 100 ? 260.906 336.147 442.784 1.00 89.54  ? 100 LEU A CD2 1 
ATOM 2112 N N   . ARG C 3 101 ? 264.179 338.828 445.889 1.00 89.61  ? 101 ARG A N   1 
ATOM 2113 C CA  . ARG C 3 101 ? 264.546 340.222 445.691 1.00 89.61  ? 101 ARG A CA  1 
ATOM 2114 C C   . ARG C 3 101 ? 266.051 340.380 445.566 1.00 89.61  ? 101 ARG A C   1 
ATOM 2115 O O   . ARG C 3 101 ? 266.525 341.122 444.705 1.00 89.61  ? 101 ARG A O   1 
ATOM 2116 C CB  . ARG C 3 101 ? 264.020 341.069 446.836 1.00 89.61  ? 101 ARG A CB  1 
ATOM 2117 C CG  . ARG C 3 101 ? 264.191 342.537 446.632 1.00 89.61  ? 101 ARG A CG  1 
ATOM 2118 C CD  . ARG C 3 101 ? 263.559 343.291 447.769 1.00 89.61  ? 101 ARG A CD  1 
ATOM 2119 N NE  . ARG C 3 101 ? 263.861 344.710 447.712 1.00 89.61  ? 101 ARG A NE  1 
ATOM 2120 C CZ  . ARG C 3 101 ? 263.497 345.579 448.643 1.00 89.61  ? 101 ARG A CZ  1 
ATOM 2121 N NH1 . ARG C 3 101 ? 262.821 345.164 449.701 1.00 89.61  ? 101 ARG A NH1 1 
ATOM 2122 N NH2 . ARG C 3 101 ? 263.813 346.855 448.519 1.00 89.61  ? 101 ARG A NH2 1 
ATOM 2123 N N   . ARG C 3 102 ? 266.813 339.659 446.385 1.00 86.73  ? 102 ARG A N   1 
ATOM 2124 C CA  . ARG C 3 102 ? 268.264 339.765 446.352 1.00 86.73  ? 102 ARG A CA  1 
ATOM 2125 C C   . ARG C 3 102 ? 268.855 339.191 445.076 1.00 86.73  ? 102 ARG A C   1 
ATOM 2126 O O   . ARG C 3 102 ? 269.898 339.663 444.619 1.00 86.73  ? 102 ARG A O   1 
ATOM 2127 C CB  . ARG C 3 102 ? 268.861 339.061 447.563 1.00 86.73  ? 102 ARG A CB  1 
ATOM 2128 C CG  . ARG C 3 102 ? 270.298 339.406 447.839 1.00 86.73  ? 102 ARG A CG  1 
ATOM 2129 C CD  . ARG C 3 102 ? 270.841 338.535 448.941 1.00 86.73  ? 102 ARG A CD  1 
ATOM 2130 N NE  . ARG C 3 102 ? 272.125 339.011 449.432 1.00 86.73  ? 102 ARG A NE  1 
ATOM 2131 C CZ  . ARG C 3 102 ? 273.294 338.600 448.968 1.00 86.73  ? 102 ARG A CZ  1 
ATOM 2132 N NH1 . ARG C 3 102 ? 273.342 337.700 448.001 1.00 86.73  ? 102 ARG A NH1 1 
ATOM 2133 N NH2 . ARG C 3 102 ? 274.412 339.081 449.475 1.00 86.73  ? 102 ARG A NH2 1 
ATOM 2134 N N   . LYS C 3 103 ? 268.207 338.199 444.476 1.00 85.59  ? 103 LYS A N   1 
ATOM 2135 C CA  . LYS C 3 103 ? 268.693 337.684 443.206 1.00 85.59  ? 103 LYS A CA  1 
ATOM 2136 C C   . LYS C 3 103 ? 268.331 338.579 442.037 1.00 85.59  ? 103 LYS A C   1 
ATOM 2137 O O   . LYS C 3 103 ? 268.905 338.425 440.959 1.00 85.59  ? 103 LYS A O   1 
ATOM 2138 C CB  . LYS C 3 103 ? 268.152 336.279 442.955 1.00 85.59  ? 103 LYS A CB  1 
ATOM 2139 C CG  . LYS C 3 103 ? 268.908 335.199 443.686 1.00 85.59  ? 103 LYS A CG  1 
ATOM 2140 C CD  . LYS C 3 103 ? 268.121 333.911 443.735 1.00 85.59  ? 103 LYS A CD  1 
ATOM 2141 C CE  . LYS C 3 103 ? 267.784 333.422 442.345 1.00 85.59  ? 103 LYS A CE  1 
ATOM 2142 N NZ  . LYS C 3 103 ? 266.976 332.178 442.389 1.00 85.59  ? 103 LYS A NZ  1 
ATOM 2143 N N   . LEU C 3 104 ? 267.396 339.506 442.216 1.00 83.76  ? 104 LEU A N   1 
ATOM 2144 C CA  . LEU C 3 104 ? 267.035 340.413 441.141 1.00 83.76  ? 104 LEU A CA  1 
ATOM 2145 C C   . LEU C 3 104 ? 267.708 341.769 441.250 1.00 83.76  ? 104 LEU A C   1 
ATOM 2146 O O   . LEU C 3 104 ? 267.770 342.488 440.251 1.00 83.76  ? 104 LEU A O   1 
ATOM 2147 C CB  . LEU C 3 104 ? 265.520 340.614 441.093 1.00 83.76  ? 104 LEU A CB  1 
ATOM 2148 C CG  . LEU C 3 104 ? 264.702 339.444 440.557 1.00 83.76  ? 104 LEU A CG  1 
ATOM 2149 C CD1 . LEU C 3 104 ? 263.269 339.855 440.361 1.00 83.76  ? 104 LEU A CD1 1 
ATOM 2150 C CD2 . LEU C 3 104 ? 265.273 338.949 439.259 1.00 83.76  ? 104 LEU A CD2 1 
ATOM 2151 N N   . GLU C 3 105 ? 268.211 342.141 442.423 1.00 89.71  ? 105 GLU A N   1 
ATOM 2152 C CA  . GLU C 3 105 ? 268.941 343.393 442.529 1.00 89.71  ? 105 GLU A CA  1 
ATOM 2153 C C   . GLU C 3 105 ? 270.420 343.240 442.225 1.00 89.71  ? 105 GLU A C   1 
ATOM 2154 O O   . GLU C 3 105 ? 271.182 344.173 442.479 1.00 89.71  ? 105 GLU A O   1 
ATOM 2155 C CB  . GLU C 3 105 ? 268.784 344.014 443.922 1.00 89.71  ? 105 GLU A CB  1 
ATOM 2156 C CG  . GLU C 3 105 ? 267.356 344.219 444.470 1.00 89.71  ? 105 GLU A CG  1 
ATOM 2157 C CD  . GLU C 3 105 ? 266.348 344.928 443.561 1.00 89.71  ? 105 GLU A CD  1 
ATOM 2158 O OE1 . GLU C 3 105 ? 265.139 344.805 443.841 1.00 89.71  ? 105 GLU A OE1 1 
ATOM 2159 O OE2 . GLU C 3 105 ? 266.716 345.655 442.624 1.00 89.71  ? 105 GLU A OE2 1 
ATOM 2160 N N   . LEU C 3 106 ? 270.854 342.089 441.716 1.00 83.74  ? 106 LEU A N   1 
ATOM 2161 C CA  . LEU C 3 106 ? 272.203 342.004 441.182 1.00 83.74  ? 106 LEU A CA  1 
ATOM 2162 C C   . LEU C 3 106 ? 272.337 342.779 439.886 1.00 83.74  ? 106 LEU A C   1 
ATOM 2163 O O   . LEU C 3 106 ? 273.438 343.223 439.554 1.00 83.74  ? 106 LEU A O   1 
ATOM 2164 C CB  . LEU C 3 106 ? 272.601 340.553 440.945 1.00 83.74  ? 106 LEU A CB  1 
ATOM 2165 C CG  . LEU C 3 106 ? 272.910 339.683 442.154 1.00 83.74  ? 106 LEU A CG  1 
ATOM 2166 C CD1 . LEU C 3 106 ? 273.594 338.421 441.708 1.00 83.74  ? 106 LEU A CD1 1 
ATOM 2167 C CD2 . LEU C 3 106 ? 273.788 340.426 443.108 1.00 83.74  ? 106 LEU A CD2 1 
ATOM 2168 N N   . PHE C 3 107 ? 271.246 342.946 439.150 1.00 82.79  ? 107 PHE A N   1 
ATOM 2169 C CA  . PHE C 3 107 ? 271.244 343.690 437.906 1.00 82.79  ? 107 PHE A CA  1 
ATOM 2170 C C   . PHE C 3 107 ? 270.360 344.915 438.052 1.00 82.79  ? 107 PHE A C   1 
ATOM 2171 O O   . PHE C 3 107 ? 269.538 345.007 438.963 1.00 82.79  ? 107 PHE A O   1 
ATOM 2172 C CB  . PHE C 3 107 ? 270.747 342.831 436.753 1.00 82.79  ? 107 PHE A CB  1 
ATOM 2173 C CG  . PHE C 3 107 ? 271.305 341.455 436.754 1.00 82.79  ? 107 PHE A CG  1 
ATOM 2174 C CD1 . PHE C 3 107 ? 272.597 341.228 436.343 1.00 82.79  ? 107 PHE A CD1 1 
ATOM 2175 C CD2 . PHE C 3 107 ? 270.541 340.390 437.168 1.00 82.79  ? 107 PHE A CD2 1 
ATOM 2176 C CE1 . PHE C 3 107 ? 273.118 339.962 436.340 1.00 82.79  ? 107 PHE A CE1 1 
ATOM 2177 C CE2 . PHE C 3 107 ? 271.057 339.120 437.170 1.00 82.79  ? 107 PHE A CE2 1 
ATOM 2178 C CZ  . PHE C 3 107 ? 272.347 338.908 436.755 1.00 82.79  ? 107 PHE A CZ  1 
ATOM 2179 N N   . THR C 3 108 ? 270.535 345.861 437.138 1.00 81.45  ? 108 THR A N   1 
ATOM 2180 C CA  . THR C 3 108 ? 269.777 347.098 437.176 1.00 81.45  ? 108 THR A CA  1 
ATOM 2181 C C   . THR C 3 108 ? 268.583 347.079 436.232 1.00 81.45  ? 108 THR A C   1 
ATOM 2182 O O   . THR C 3 108 ? 267.463 347.376 436.653 1.00 81.45  ? 108 THR A O   1 
ATOM 2183 C CB  . THR C 3 108 ? 270.701 348.276 436.859 1.00 81.45  ? 108 THR A CB  1 
ATOM 2184 O OG1 . THR C 3 108 ? 271.609 348.467 437.946 1.00 81.45  ? 108 THR A OG1 1 
ATOM 2185 C CG2 . THR C 3 108 ? 269.920 349.543 436.651 1.00 81.45  ? 108 THR A CG2 1 
ATOM 2186 N N   . TYR C 3 109 ? 268.780 346.708 434.973 1.00 82.80  ? 109 TYR A N   1 
ATOM 2187 C CA  . TYR C 3 109 ? 267.695 346.672 434.002 1.00 82.80  ? 109 TYR A CA  1 
ATOM 2188 C C   . TYR C 3 109 ? 267.439 345.236 433.584 1.00 82.80  ? 109 TYR A C   1 
ATOM 2189 O O   . TYR C 3 109 ? 268.358 344.547 433.139 1.00 82.80  ? 109 TYR A O   1 
ATOM 2190 C CB  . TYR C 3 109 ? 268.021 347.535 432.790 1.00 82.80  ? 109 TYR A CB  1 
ATOM 2191 C CG  . TYR C 3 109 ? 268.283 348.957 433.167 1.00 82.80  ? 109 TYR A CG  1 
ATOM 2192 C CD1 . TYR C 3 109 ? 267.342 349.680 433.865 1.00 82.80  ? 109 TYR A CD1 1 
ATOM 2193 C CD2 . TYR C 3 109 ? 269.474 349.571 432.845 1.00 82.80  ? 109 TYR A CD2 1 
ATOM 2194 C CE1 . TYR C 3 109 ? 267.570 350.977 434.225 1.00 82.80  ? 109 TYR A CE1 1 
ATOM 2195 C CE2 . TYR C 3 109 ? 269.715 350.869 433.204 1.00 82.80  ? 109 TYR A CE2 1 
ATOM 2196 C CZ  . TYR C 3 109 ? 268.758 351.566 433.893 1.00 82.80  ? 109 TYR A CZ  1 
ATOM 2197 O OH  . TYR C 3 109 ? 268.983 352.867 434.257 1.00 82.80  ? 109 TYR A OH  1 
ATOM 2198 N N   . LEU C 3 110 ? 266.197 344.793 433.722 1.00 82.02  ? 110 LEU A N   1 
ATOM 2199 C CA  . LEU C 3 110 ? 265.781 343.458 433.335 1.00 82.02  ? 110 LEU A CA  1 
ATOM 2200 C C   . LEU C 3 110 ? 264.697 343.538 432.273 1.00 82.02  ? 110 LEU A C   1 
ATOM 2201 O O   . LEU C 3 110 ? 264.125 344.599 432.023 1.00 82.02  ? 110 LEU A O   1 
ATOM 2202 C CB  . LEU C 3 110 ? 265.248 342.678 434.528 1.00 82.02  ? 110 LEU A CB  1 
ATOM 2203 C CG  . LEU C 3 110 ? 266.278 342.357 435.587 1.00 82.02  ? 110 LEU A CG  1 
ATOM 2204 C CD1 . LEU C 3 110 ? 265.583 341.817 436.792 1.00 82.02  ? 110 LEU A CD1 1 
ATOM 2205 C CD2 . LEU C 3 110 ? 267.234 341.344 435.039 1.00 82.02  ? 110 LEU A CD2 1 
ATOM 2206 N N   . ARG C 3 111 ? 264.407 342.391 431.668 1.00 84.66  ? 111 ARG A N   1 
ATOM 2207 C CA  . ARG C 3 111 ? 263.357 342.295 430.661 1.00 84.66  ? 111 ARG A CA  1 
ATOM 2208 C C   . ARG C 3 111 ? 262.934 340.840 430.569 1.00 84.66  ? 111 ARG A C   1 
ATOM 2209 O O   . ARG C 3 111 ? 263.722 340.003 430.132 1.00 84.66  ? 111 ARG A O   1 
ATOM 2210 C CB  . ARG C 3 111 ? 263.847 342.798 429.316 1.00 84.66  ? 111 ARG A CB  1 
ATOM 2211 C CG  . ARG C 3 111 ? 262.840 342.633 428.220 1.00 84.66  ? 111 ARG A CG  1 
ATOM 2212 C CD  . ARG C 3 111 ? 263.499 342.708 426.870 1.00 84.66  ? 111 ARG A CD  1 
ATOM 2213 N NE  . ARG C 3 111 ? 262.514 342.800 425.805 1.00 84.66  ? 111 ARG A NE  1 
ATOM 2214 C CZ  . ARG C 3 111 ? 262.049 343.945 425.329 1.00 84.66  ? 111 ARG A CZ  1 
ATOM 2215 N NH1 . ARG C 3 111 ? 262.489 345.087 425.823 1.00 84.66  ? 111 ARG A NH1 1 
ATOM 2216 N NH2 . ARG C 3 111 ? 261.154 343.945 424.356 1.00 84.66  ? 111 ARG A NH2 1 
ATOM 2217 N N   . PHE C 3 112 ? 261.702 340.531 430.962 1.00 83.84  ? 112 PHE A N   1 
ATOM 2218 C CA  . PHE C 3 112 ? 261.254 339.150 430.948 1.00 83.84  ? 112 PHE A CA  1 
ATOM 2219 C C   . PHE C 3 112 ? 259.754 339.060 430.727 1.00 83.84  ? 112 PHE A C   1 
ATOM 2220 O O   . PHE C 3 112 ? 259.008 339.989 431.032 1.00 83.84  ? 112 PHE A O   1 
ATOM 2221 C CB  . PHE C 3 112 ? 261.612 338.429 432.248 1.00 83.84  ? 112 PHE A CB  1 
ATOM 2222 C CG  . PHE C 3 112 ? 261.307 339.206 433.498 1.00 83.84  ? 112 PHE A CG  1 
ATOM 2223 C CD1 . PHE C 3 112 ? 260.040 339.210 434.042 1.00 83.84  ? 112 PHE A CD1 1 
ATOM 2224 C CD2 . PHE C 3 112 ? 262.305 339.878 434.159 1.00 83.84  ? 112 PHE A CD2 1 
ATOM 2225 C CE1 . PHE C 3 112 ? 259.768 339.902 435.190 1.00 83.84  ? 112 PHE A CE1 1 
ATOM 2226 C CE2 . PHE C 3 112 ? 262.036 340.569 435.315 1.00 83.84  ? 112 PHE A CE2 1 
ATOM 2227 C CZ  . PHE C 3 112 ? 260.766 340.579 435.828 1.00 83.84  ? 112 PHE A CZ  1 
ATOM 2228 N N   . ASP C 3 113 ? 259.320 337.911 430.219 1.00 91.51  ? 113 ASP A N   1 
ATOM 2229 C CA  . ASP C 3 113 ? 257.917 337.537 430.247 1.00 91.51  ? 113 ASP A CA  1 
ATOM 2230 C C   . ASP C 3 113 ? 257.576 336.986 431.625 1.00 91.51  ? 113 ASP A C   1 
ATOM 2231 O O   . ASP C 3 113 ? 258.421 336.922 432.517 1.00 91.51  ? 113 ASP A O   1 
ATOM 2232 C CB  . ASP C 3 113 ? 257.618 336.514 429.161 1.00 91.51  ? 113 ASP A CB  1 
ATOM 2233 C CG  . ASP C 3 113 ? 257.838 337.067 427.778 1.00 91.51  ? 113 ASP A CG  1 
ATOM 2234 O OD1 . ASP C 3 113 ? 258.691 337.965 427.633 1.00 91.51  ? 113 ASP A OD1 1 
ATOM 2235 O OD2 . ASP C 3 113 ? 257.164 336.605 426.836 1.00 91.51  ? 113 ASP A OD2 1 
ATOM 2236 N N   . LEU C 3 114 ? 256.336 336.558 431.818 1.00 86.12  ? 114 LEU A N   1 
ATOM 2237 C CA  . LEU C 3 114 ? 255.945 336.080 433.132 1.00 86.12  ? 114 LEU A CA  1 
ATOM 2238 C C   . LEU C 3 114 ? 255.068 334.849 433.007 1.00 86.12  ? 114 LEU A C   1 
ATOM 2239 O O   . LEU C 3 114 ? 254.368 334.664 432.012 1.00 86.12  ? 114 LEU A O   1 
ATOM 2240 C CB  . LEU C 3 114 ? 255.215 337.161 433.916 1.00 86.12  ? 114 LEU A CB  1 
ATOM 2241 C CG  . LEU C 3 114 ? 255.519 337.164 435.403 1.00 86.12  ? 114 LEU A CG  1 
ATOM 2242 C CD1 . LEU C 3 114 ? 257.003 337.217 435.589 1.00 86.12  ? 114 LEU A CD1 1 
ATOM 2243 C CD2 . LEU C 3 114 ? 254.878 338.353 436.057 1.00 86.12  ? 114 LEU A CD2 1 
ATOM 2244 N N   . GLU C 3 115 ? 255.116 334.006 434.032 1.00 91.86  ? 115 GLU A N   1 
ATOM 2245 C CA  . GLU C 3 115 ? 254.305 332.797 434.098 1.00 91.86  ? 115 GLU A CA  1 
ATOM 2246 C C   . GLU C 3 115 ? 253.830 332.609 435.522 1.00 91.86  ? 115 GLU A C   1 
ATOM 2247 O O   . GLU C 3 115 ? 254.646 332.420 436.424 1.00 91.86  ? 115 GLU A O   1 
ATOM 2248 C CB  . GLU C 3 115 ? 255.088 331.568 433.662 1.00 91.86  ? 115 GLU A CB  1 
ATOM 2249 C CG  . GLU C 3 115 ? 255.269 331.415 432.191 1.00 91.86  ? 115 GLU A CG  1 
ATOM 2250 C CD  . GLU C 3 115 ? 255.143 329.969 431.796 1.00 91.86  ? 115 GLU A CD  1 
ATOM 2251 O OE1 . GLU C 3 115 ? 254.288 329.290 432.391 1.00 91.86  ? 115 GLU A OE1 1 
ATOM 2252 O OE2 . GLU C 3 115 ? 255.883 329.496 430.914 1.00 91.86  ? 115 GLU A OE2 1 
ATOM 2253 N N   . LEU C 3 116 ? 252.522 332.626 435.723 1.00 83.42  ? 116 LEU A N   1 
ATOM 2254 C CA  . LEU C 3 116 ? 251.956 332.518 437.052 1.00 83.42  ? 116 LEU A CA  1 
ATOM 2255 C C   . LEU C 3 116 ? 251.121 331.253 437.137 1.00 83.42  ? 116 LEU A C   1 
ATOM 2256 O O   . LEU C 3 116 ? 250.435 330.883 436.185 1.00 83.42  ? 116 LEU A O   1 
ATOM 2257 C CB  . LEU C 3 116 ? 251.103 333.735 437.391 1.00 83.42  ? 116 LEU A CB  1 
ATOM 2258 C CG  . LEU C 3 116 ? 251.862 335.033 437.657 1.00 83.42  ? 116 LEU A CG  1 
ATOM 2259 C CD1 . LEU C 3 116 ? 252.064 335.836 436.400 1.00 83.42  ? 116 LEU A CD1 1 
ATOM 2260 C CD2 . LEU C 3 116 ? 251.154 335.863 438.675 1.00 83.42  ? 116 LEU A CD2 1 
ATOM 2261 N N   . THR C 3 117 ? 251.190 330.584 438.281 1.00 78.80  ? 117 THR A N   1 
ATOM 2262 C CA  . THR C 3 117 ? 250.442 329.358 438.493 1.00 78.80  ? 117 THR A CA  1 
ATOM 2263 C C   . THR C 3 117 ? 249.925 329.332 439.916 1.00 78.80  ? 117 THR A C   1 
ATOM 2264 O O   . THR C 3 117 ? 250.699 329.468 440.863 1.00 78.80  ? 117 THR A O   1 
ATOM 2265 C CB  . THR C 3 117 ? 251.303 328.137 438.238 1.00 78.80  ? 117 THR A CB  1 
ATOM 2266 O OG1 . THR C 3 117 ? 251.760 328.164 436.886 1.00 78.80  ? 117 THR A OG1 1 
ATOM 2267 C CG2 . THR C 3 117 ? 250.501 326.893 438.445 1.00 78.80  ? 117 THR A CG2 1 
ATOM 2268 N N   . PHE C 3 118 ? 248.619 329.149 440.063 1.00 75.52  ? 118 PHE A N   1 
ATOM 2269 C CA  . PHE C 3 118 ? 247.938 329.271 441.341 1.00 75.52  ? 118 PHE A CA  1 
ATOM 2270 C C   . PHE C 3 118 ? 247.536 327.892 441.827 1.00 75.52  ? 118 PHE A C   1 
ATOM 2271 O O   . PHE C 3 118 ? 246.887 327.143 441.098 1.00 75.52  ? 118 PHE A O   1 
ATOM 2272 C CB  . PHE C 3 118 ? 246.698 330.146 441.207 1.00 75.52  ? 118 PHE A CB  1 
ATOM 2273 C CG  . PHE C 3 118 ? 246.882 331.323 440.309 1.00 75.52  ? 118 PHE A CG  1 
ATOM 2274 C CD1 . PHE C 3 118 ? 247.463 332.472 440.776 1.00 75.52  ? 118 PHE A CD1 1 
ATOM 2275 C CD2 . PHE C 3 118 ? 246.454 331.283 439.000 1.00 75.52  ? 118 PHE A CD2 1 
ATOM 2276 C CE1 . PHE C 3 118 ? 247.624 333.554 439.955 1.00 75.52  ? 118 PHE A CE1 1 
ATOM 2277 C CE2 . PHE C 3 118 ? 246.618 332.361 438.177 1.00 75.52  ? 118 PHE A CE2 1 
ATOM 2278 C CZ  . PHE C 3 118 ? 247.200 333.496 438.654 1.00 75.52  ? 118 PHE A CZ  1 
ATOM 2279 N N   . VAL C 3 119 ? 247.898 327.565 443.054 1.00 74.93  ? 119 VAL A N   1 
ATOM 2280 C CA  . VAL C 3 119 ? 247.554 326.287 443.656 1.00 74.93  ? 119 VAL A CA  1 
ATOM 2281 C C   . VAL C 3 119 ? 246.437 326.552 444.654 1.00 74.93  ? 119 VAL A C   1 
ATOM 2282 O O   . VAL C 3 119 ? 246.691 326.881 445.815 1.00 74.93  ? 119 VAL A O   1 
ATOM 2283 C CB  . VAL C 3 119 ? 248.760 325.635 444.326 1.00 74.93  ? 119 VAL A CB  1 
ATOM 2284 C CG1 . VAL C 3 119 ? 248.412 324.249 444.772 1.00 74.93  ? 119 VAL A CG1 1 
ATOM 2285 C CG2 . VAL C 3 119 ? 249.908 325.604 443.365 1.00 74.93  ? 119 VAL A CG2 1 
ATOM 2286 N N   . ILE C 3 120 ? 245.196 326.396 444.211 1.00 77.20  ? 120 ILE A N   1 
ATOM 2287 C CA  . ILE C 3 120 ? 244.024 326.790 444.983 1.00 77.20  ? 120 ILE A CA  1 
ATOM 2288 C C   . ILE C 3 120 ? 243.433 325.566 445.658 1.00 77.20  ? 120 ILE A C   1 
ATOM 2289 O O   . ILE C 3 120 ? 243.143 324.564 444.997 1.00 77.20  ? 120 ILE A O   1 
ATOM 2290 C CB  . ILE C 3 120 ? 242.981 327.465 444.084 1.00 77.20  ? 120 ILE A CB  1 
ATOM 2291 C CG1 . ILE C 3 120 ? 243.566 328.719 443.455 1.00 77.20  ? 120 ILE A CG1 1 
ATOM 2292 C CG2 . ILE C 3 120 ? 241.753 327.812 444.874 1.00 77.20  ? 120 ILE A CG2 1 
ATOM 2293 C CD1 . ILE C 3 120 ? 242.602 329.441 442.569 1.00 77.20  ? 120 ILE A CD1 1 
ATOM 2294 N N   . THR C 3 121 ? 243.246 325.645 446.968 1.00 87.37  ? 121 THR A N   1 
ATOM 2295 C CA  . THR C 3 121 ? 242.589 324.598 447.728 1.00 87.37  ? 121 THR A CA  1 
ATOM 2296 C C   . THR C 3 121 ? 241.536 325.220 448.628 1.00 87.37  ? 121 THR A C   1 
ATOM 2297 O O   . THR C 3 121 ? 241.543 326.423 448.885 1.00 87.37  ? 121 THR A O   1 
ATOM 2298 C CB  . THR C 3 121 ? 243.590 323.804 448.563 1.00 87.37  ? 121 THR A CB  1 
ATOM 2299 O OG1 . THR C 3 121 ? 242.882 322.905 449.424 1.00 87.37  ? 121 THR A OG1 1 
ATOM 2300 C CG2 . THR C 3 121 ? 244.428 324.743 449.391 1.00 87.37  ? 121 THR A CG2 1 
ATOM 2301 N N   . SER C 3 122 ? 240.627 324.388 449.119 1.00 88.99  ? 122 SER A N   1 
ATOM 2302 C CA  . SER C 3 122 ? 239.527 324.840 449.951 1.00 88.99  ? 122 SER A CA  1 
ATOM 2303 C C   . SER C 3 122 ? 239.514 324.075 451.264 1.00 88.99  ? 122 SER A C   1 
ATOM 2304 O O   . SER C 3 122 ? 240.167 323.044 451.416 1.00 88.99  ? 122 SER A O   1 
ATOM 2305 C CB  . SER C 3 122 ? 238.189 324.666 449.232 1.00 88.99  ? 122 SER A CB  1 
ATOM 2306 O OG  . SER C 3 122 ? 238.277 325.123 447.899 1.00 88.99  ? 122 SER A OG  1 
ATOM 2307 N N   . ALA C 3 123 ? 238.747 324.593 452.216 1.00 94.09  ? 123 ALA A N   1 
ATOM 2308 C CA  . ALA C 3 123 ? 238.629 323.975 453.529 1.00 94.09  ? 123 ALA A CA  1 
ATOM 2309 C C   . ALA C 3 123 ? 237.288 324.364 454.118 1.00 94.09  ? 123 ALA A C   1 
ATOM 2310 O O   . ALA C 3 123 ? 236.919 325.539 454.086 1.00 94.09  ? 123 ALA A O   1 
ATOM 2311 C CB  . ALA C 3 123 ? 239.763 324.417 454.448 1.00 94.09  ? 123 ALA A CB  1 
ATOM 2312 N N   . GLN C 3 124 ? 236.567 323.392 454.658 1.00 101.18 ? 124 GLN A N   1 
ATOM 2313 C CA  . GLN C 3 124 ? 235.202 323.612 455.110 1.00 101.18 ? 124 GLN A CA  1 
ATOM 2314 C C   . GLN C 3 124 ? 235.202 324.324 456.455 1.00 101.18 ? 124 GLN A C   1 
ATOM 2315 O O   . GLN C 3 124 ? 235.824 323.856 457.411 1.00 101.18 ? 124 GLN A O   1 
ATOM 2316 C CB  . GLN C 3 124 ? 234.449 322.292 455.212 1.00 101.18 ? 124 GLN A CB  1 
ATOM 2317 C CG  . GLN C 3 124 ? 233.064 322.439 455.781 1.00 101.18 ? 124 GLN A CG  1 
ATOM 2318 C CD  . GLN C 3 124 ? 232.408 321.110 456.050 1.00 101.18 ? 124 GLN A CD  1 
ATOM 2319 O OE1 . GLN C 3 124 ? 232.840 320.078 455.542 1.00 101.18 ? 124 GLN A OE1 1 
ATOM 2320 N NE2 . GLN C 3 124 ? 231.361 321.125 456.860 1.00 101.18 ? 124 GLN A NE2 1 
ATOM 2321 N N   . GLN C 3 125 ? 234.506 325.447 456.524 1.00 107.68 ? 125 GLN A N   1 
ATOM 2322 C CA  . GLN C 3 125 ? 234.299 326.165 457.767 1.00 107.68 ? 125 GLN A CA  1 
ATOM 2323 C C   . GLN C 3 125 ? 233.187 325.501 458.570 1.00 107.68 ? 125 GLN A C   1 
ATOM 2324 O O   . GLN C 3 125 ? 232.346 324.800 458.005 1.00 107.68 ? 125 GLN A O   1 
ATOM 2325 C CB  . GLN C 3 125 ? 233.950 327.617 457.464 1.00 107.68 ? 125 GLN A CB  1 
ATOM 2326 C CG  . GLN C 3 125 ? 235.146 328.446 457.097 1.00 107.68 ? 125 GLN A CG  1 
ATOM 2327 C CD  . GLN C 3 125 ? 236.220 328.376 458.144 1.00 107.68 ? 125 GLN A CD  1 
ATOM 2328 O OE1 . GLN C 3 125 ? 237.246 327.729 457.956 1.00 107.68 ? 125 GLN A OE1 1 
ATOM 2329 N NE2 . GLN C 3 125 ? 235.989 329.038 459.266 1.00 107.68 ? 125 GLN A NE2 1 
ATOM 2330 N N   . PRO C 3 126 ? 233.166 325.686 459.902 1.00 113.64 ? 126 PRO A N   1 
ATOM 2331 C CA  . PRO C 3 126 ? 232.098 325.072 460.703 1.00 113.64 ? 126 PRO A CA  1 
ATOM 2332 C C   . PRO C 3 126 ? 230.730 325.681 460.456 1.00 113.64 ? 126 PRO A C   1 
ATOM 2333 O O   . PRO C 3 126 ? 230.448 326.807 460.874 1.00 113.64 ? 126 PRO A O   1 
ATOM 2334 C CB  . PRO C 3 126 ? 232.556 325.315 462.145 1.00 113.64 ? 126 PRO A CB  1 
ATOM 2335 C CG  . PRO C 3 126 ? 233.510 326.440 462.056 1.00 113.64 ? 126 PRO A CG  1 
ATOM 2336 C CD  . PRO C 3 126 ? 234.220 326.240 460.766 1.00 113.64 ? 126 PRO A CD  1 
ATOM 2337 N N   . SER C 3 127 ? 229.867 324.923 459.789 1.00 128.34 ? 127 SER A N   1 
ATOM 2338 C CA  . SER C 3 127 ? 228.511 325.350 459.491 1.00 128.34 ? 127 SER A CA  1 
ATOM 2339 C C   . SER C 3 127 ? 227.621 325.092 460.701 1.00 128.34 ? 127 SER A C   1 
ATOM 2340 O O   . SER C 3 127 ? 228.093 324.721 461.779 1.00 128.34 ? 127 SER A O   1 
ATOM 2341 C CB  . SER C 3 127 ? 227.991 324.633 458.248 1.00 128.34 ? 127 SER A CB  1 
ATOM 2342 O OG  . SER C 3 127 ? 226.575 324.671 458.194 1.00 128.34 ? 127 SER A OG  1 
ATOM 2343 N N   . THR C 3 128 ? 226.312 325.279 460.539 1.00 137.82 ? 128 THR A N   1 
ATOM 2344 C CA  . THR C 3 128 ? 225.425 325.092 461.680 1.00 137.82 ? 128 THR A CA  1 
ATOM 2345 C C   . THR C 3 128 ? 225.058 323.618 461.897 1.00 137.82 ? 128 THR A C   1 
ATOM 2346 O O   . THR C 3 128 ? 225.512 323.013 462.876 1.00 137.82 ? 128 THR A O   1 
ATOM 2347 C CB  . THR C 3 128 ? 224.200 326.025 461.555 1.00 137.82 ? 128 THR A CB  1 
ATOM 2348 O OG1 . THR C 3 128 ? 223.288 325.808 462.640 1.00 137.82 ? 128 THR A OG1 1 
ATOM 2349 C CG2 . THR C 3 128 ? 223.505 326.012 460.168 1.00 137.82 ? 128 THR A CG2 1 
ATOM 2350 N N   . ALA C 3 129 ? 224.318 323.003 460.972 1.00 140.56 ? 129 ALA A N   1 
ATOM 2351 C CA  . ALA C 3 129 ? 223.764 321.658 461.151 1.00 140.56 ? 129 ALA A CA  1 
ATOM 2352 C C   . ALA C 3 129 ? 223.145 321.195 459.837 1.00 140.56 ? 129 ALA A C   1 
ATOM 2353 O O   . ALA C 3 129 ? 223.241 321.872 458.806 1.00 140.56 ? 129 ALA A O   1 
ATOM 2354 C CB  . ALA C 3 129 ? 222.711 321.615 462.263 1.00 140.56 ? 129 ALA A CB  1 
ATOM 2355 N N   . SER C 3 130 ? 222.499 320.025 459.900 1.00 139.60 ? 130 SER A N   1 
ATOM 2356 C CA  . SER C 3 130 ? 221.495 319.527 458.950 1.00 139.60 ? 130 SER A CA  1 
ATOM 2357 C C   . SER C 3 130 ? 222.063 319.307 457.548 1.00 139.60 ? 130 SER A C   1 
ATOM 2358 O O   . SER C 3 130 ? 221.643 319.943 456.579 1.00 139.60 ? 130 SER A O   1 
ATOM 2359 C CB  . SER C 3 130 ? 220.255 320.435 458.892 1.00 139.60 ? 130 SER A CB  1 
ATOM 2360 O OG  . SER C 3 130 ? 220.534 321.758 458.463 1.00 139.60 ? 130 SER A OG  1 
ATOM 2361 N N   . SER C 3 131 ? 223.021 318.377 457.469 1.00 135.04 ? 131 SER A N   1 
ATOM 2362 C CA  . SER C 3 131 ? 223.413 317.679 456.240 1.00 135.04 ? 131 SER A CA  1 
ATOM 2363 C C   . SER C 3 131 ? 223.912 318.644 455.160 1.00 135.04 ? 131 SER A C   1 
ATOM 2364 O O   . SER C 3 131 ? 223.282 318.841 454.121 1.00 135.04 ? 131 SER A O   1 
ATOM 2365 C CB  . SER C 3 131 ? 222.252 316.835 455.712 1.00 135.04 ? 131 SER A CB  1 
ATOM 2366 O OG  . SER C 3 131 ? 221.422 317.621 454.878 1.00 135.04 ? 131 SER A OG  1 
ATOM 2367 N N   . VAL C 3 132 ? 225.047 319.272 455.458 1.00 126.44 ? 132 VAL A N   1 
ATOM 2368 C CA  . VAL C 3 132 ? 225.672 320.168 454.497 1.00 126.44 ? 132 VAL A CA  1 
ATOM 2369 C C   . VAL C 3 132 ? 226.219 319.370 453.319 1.00 126.44 ? 132 VAL A C   1 
ATOM 2370 O O   . VAL C 3 132 ? 226.941 318.379 453.486 1.00 126.44 ? 132 VAL A O   1 
ATOM 2371 C CB  . VAL C 3 132 ? 226.759 321.010 455.188 1.00 126.44 ? 132 VAL A CB  1 
ATOM 2372 C CG1 . VAL C 3 132 ? 227.619 320.153 456.099 1.00 126.44 ? 132 VAL A CG1 1 
ATOM 2373 C CG2 . VAL C 3 132 ? 227.622 321.727 454.166 1.00 126.44 ? 132 VAL A CG2 1 
ATOM 2374 N N   . ASP C 3 133 ? 225.833 319.777 452.115 1.00 125.04 ? 133 ASP A N   1 
ATOM 2375 C CA  . ASP C 3 133 ? 226.339 319.164 450.895 1.00 125.04 ? 133 ASP A CA  1 
ATOM 2376 C C   . ASP C 3 133 ? 226.458 320.279 449.872 1.00 125.04 ? 133 ASP A C   1 
ATOM 2377 O O   . ASP C 3 133 ? 225.519 321.057 449.687 1.00 125.04 ? 133 ASP A O   1 
ATOM 2378 C CB  . ASP C 3 133 ? 225.403 318.060 450.395 1.00 125.04 ? 133 ASP A CB  1 
ATOM 2379 C CG  . ASP C 3 133 ? 225.955 317.289 449.188 1.00 125.04 ? 133 ASP A CG  1 
ATOM 2380 O OD1 . ASP C 3 133 ? 227.020 317.631 448.631 1.00 125.04 ? 133 ASP A OD1 1 
ATOM 2381 O OD2 . ASP C 3 133 ? 225.295 316.311 448.782 1.00 125.04 ? 133 ASP A OD2 1 
ATOM 2382 N N   . ALA C 3 134 ? 227.609 320.347 449.212 1.00 114.80 ? 134 ALA A N   1 
ATOM 2383 C CA  . ALA C 3 134 ? 227.856 321.335 448.186 1.00 114.80 ? 134 ALA A CA  1 
ATOM 2384 C C   . ALA C 3 134 ? 228.472 320.674 446.963 1.00 114.80 ? 134 ALA A C   1 
ATOM 2385 O O   . ALA C 3 134 ? 229.202 319.688 447.093 1.00 114.80 ? 134 ALA A O   1 
ATOM 2386 C CB  . ALA C 3 134 ? 228.792 322.438 448.691 1.00 114.80 ? 134 ALA A CB  1 
ATOM 2387 N N   . PRO C 3 135 ? 228.200 321.184 445.771 1.00 105.91 ? 135 PRO A N   1 
ATOM 2388 C CA  . PRO C 3 135 ? 228.874 320.690 444.569 1.00 105.91 ? 135 PRO A CA  1 
ATOM 2389 C C   . PRO C 3 135 ? 230.291 321.247 444.485 1.00 105.91 ? 135 PRO A C   1 
ATOM 2390 O O   . PRO C 3 135 ? 230.782 321.904 445.401 1.00 105.91 ? 135 PRO A O   1 
ATOM 2391 C CB  . PRO C 3 135 ? 227.995 321.209 443.431 1.00 105.91 ? 135 PRO A CB  1 
ATOM 2392 C CG  . PRO C 3 135 ? 226.709 321.588 444.074 1.00 105.91 ? 135 PRO A CG  1 
ATOM 2393 C CD  . PRO C 3 135 ? 227.078 322.064 445.429 1.00 105.91 ? 135 PRO A CD  1 
ATOM 2394 N N   . VAL C 3 136 ? 230.951 320.960 443.363 1.00 99.90  ? 136 VAL A N   1 
ATOM 2395 C CA  . VAL C 3 136 ? 232.326 321.398 443.184 1.00 99.90  ? 136 VAL A CA  1 
ATOM 2396 C C   . VAL C 3 136 ? 232.366 322.909 443.007 1.00 99.90  ? 136 VAL A C   1 
ATOM 2397 O O   . VAL C 3 136 ? 231.447 323.520 442.443 1.00 99.90  ? 136 VAL A O   1 
ATOM 2398 C CB  . VAL C 3 136 ? 232.987 320.650 442.013 1.00 99.90  ? 136 VAL A CB  1 
ATOM 2399 C CG1 . VAL C 3 136 ? 232.876 319.165 442.233 1.00 99.90  ? 136 VAL A CG1 1 
ATOM 2400 C CG2 . VAL C 3 136 ? 232.338 320.994 440.693 1.00 99.90  ? 136 VAL A CG2 1 
ATOM 2401 N N   . GLN C 3 137 ? 233.394 323.529 443.564 1.00 92.46  ? 137 GLN A N   1 
ATOM 2402 C CA  . GLN C 3 137 ? 233.485 324.976 443.581 1.00 92.46  ? 137 GLN A CA  1 
ATOM 2403 C C   . GLN C 3 137 ? 234.204 325.470 442.341 1.00 92.46  ? 137 GLN A C   1 
ATOM 2404 O O   . GLN C 3 137 ? 234.849 324.708 441.622 1.00 92.46  ? 137 GLN A O   1 
ATOM 2405 C CB  . GLN C 3 137 ? 234.207 325.449 444.833 1.00 92.46  ? 137 GLN A CB  1 
ATOM 2406 C CG  . GLN C 3 137 ? 233.502 325.074 446.104 1.00 92.46  ? 137 GLN A CG  1 
ATOM 2407 C CD  . GLN C 3 137 ? 232.252 325.887 446.322 1.00 92.46  ? 137 GLN A CD  1 
ATOM 2408 O OE1 . GLN C 3 137 ? 231.251 325.383 446.821 1.00 92.46  ? 137 GLN A OE1 1 
ATOM 2409 N NE2 . GLN C 3 137 ? 232.301 327.155 445.949 1.00 92.46  ? 137 GLN A NE2 1 
ATOM 2410 N N   . THR C 3 138 ? 234.085 326.767 442.092 1.00 84.22  ? 138 THR A N   1 
ATOM 2411 C CA  . THR C 3 138 ? 234.662 327.365 440.902 1.00 84.22  ? 138 THR A CA  1 
ATOM 2412 C C   . THR C 3 138 ? 235.205 328.730 441.281 1.00 84.22  ? 138 THR A C   1 
ATOM 2413 O O   . THR C 3 138 ? 234.519 329.501 441.953 1.00 84.22  ? 138 THR A O   1 
ATOM 2414 C CB  . THR C 3 138 ? 233.613 327.477 439.794 1.00 84.22  ? 138 THR A CB  1 
ATOM 2415 O OG1 . THR C 3 138 ? 233.125 326.175 439.470 1.00 84.22  ? 138 THR A OG1 1 
ATOM 2416 C CG2 . THR C 3 138 ? 234.209 328.071 438.547 1.00 84.22  ? 138 THR A CG2 1 
ATOM 2417 N N   . HIS C 3 139 ? 236.435 329.022 440.876 1.00 78.09  ? 139 HIS A N   1 
ATOM 2418 C CA  . HIS C 3 139 ? 237.089 330.268 441.229 1.00 78.09  ? 139 HIS A CA  1 
ATOM 2419 C C   . HIS C 3 139 ? 237.341 331.093 439.978 1.00 78.09  ? 139 HIS A C   1 
ATOM 2420 O O   . HIS C 3 139 ? 237.495 330.557 438.883 1.00 78.09  ? 139 HIS A O   1 
ATOM 2421 C CB  . HIS C 3 139 ? 238.408 330.011 441.949 1.00 78.09  ? 139 HIS A CB  1 
ATOM 2422 C CG  . HIS C 3 139 ? 238.292 329.101 443.129 1.00 78.09  ? 139 HIS A CG  1 
ATOM 2423 N ND1 . HIS C 3 139 ? 238.350 329.558 444.425 1.00 78.09  ? 139 HIS A ND1 1 
ATOM 2424 C CD2 . HIS C 3 139 ? 238.151 327.758 443.210 1.00 78.09  ? 139 HIS A CD2 1 
ATOM 2425 C CE1 . HIS C 3 139 ? 238.233 328.538 445.255 1.00 78.09  ? 139 HIS A CE1 1 
ATOM 2426 N NE2 . HIS C 3 139 ? 238.111 327.435 444.542 1.00 78.09  ? 139 HIS A NE2 1 
ATOM 2427 N N   . GLN C 3 140 ? 237.391 332.409 440.151 1.00 76.12  ? 140 GLN A N   1 
ATOM 2428 C CA  . GLN C 3 140 ? 237.674 333.332 439.059 1.00 76.12  ? 140 GLN A CA  1 
ATOM 2429 C C   . GLN C 3 140 ? 238.875 334.169 439.445 1.00 76.12  ? 140 GLN A C   1 
ATOM 2430 O O   . GLN C 3 140 ? 238.863 334.812 440.496 1.00 76.12  ? 140 GLN A O   1 
ATOM 2431 C CB  . GLN C 3 140 ? 236.482 334.235 438.768 1.00 76.12  ? 140 GLN A CB  1 
ATOM 2432 C CG  . GLN C 3 140 ? 236.845 335.460 437.969 1.00 76.12  ? 140 GLN A CG  1 
ATOM 2433 C CD  . GLN C 3 140 ? 235.678 336.374 437.741 1.00 76.12  ? 140 GLN A CD  1 
ATOM 2434 O OE1 . GLN C 3 140 ? 234.791 336.491 438.581 1.00 76.12  ? 140 GLN A OE1 1 
ATOM 2435 N NE2 . GLN C 3 140 ? 235.666 337.031 436.594 1.00 76.12  ? 140 GLN A NE2 1 
ATOM 2436 N N   . ILE C 3 141 ? 239.904 334.171 438.607 1.00 74.95  ? 141 ILE A N   1 
ATOM 2437 C CA  . ILE C 3 141 ? 241.159 334.849 438.907 1.00 74.95  ? 141 ILE A CA  1 
ATOM 2438 C C   . ILE C 3 141 ? 241.344 335.958 437.883 1.00 74.95  ? 141 ILE A C   1 
ATOM 2439 O O   . ILE C 3 141 ? 241.880 335.726 436.798 1.00 74.95  ? 141 ILE A O   1 
ATOM 2440 C CB  . ILE C 3 141 ? 242.343 333.888 438.900 1.00 74.95  ? 141 ILE A CB  1 
ATOM 2441 C CG1 . ILE C 3 141 ? 242.056 332.713 439.820 1.00 74.95  ? 141 ILE A CG1 1 
ATOM 2442 C CG2 . ILE C 3 141 ? 243.577 334.589 439.366 1.00 74.95  ? 141 ILE A CG2 1 
ATOM 2443 C CD1 . ILE C 3 141 ? 242.818 331.487 439.465 1.00 74.95  ? 141 ILE A CD1 1 
ATOM 2444 N N   . MET C 3 142 ? 240.917 337.169 438.222 1.00 82.30  ? 142 MET A N   1 
ATOM 2445 C CA  . MET C 3 142 ? 240.926 338.275 437.275 1.00 82.30  ? 142 MET A CA  1 
ATOM 2446 C C   . MET C 3 142 ? 242.275 338.966 437.279 1.00 82.30  ? 142 MET A C   1 
ATOM 2447 O O   . MET C 3 142 ? 242.931 339.065 438.315 1.00 82.30  ? 142 MET A O   1 
ATOM 2448 C CB  . MET C 3 142 ? 239.832 339.287 437.606 1.00 82.30  ? 142 MET A CB  1 
ATOM 2449 C CG  . MET C 3 142 ? 239.408 340.124 436.430 1.00 82.30  ? 142 MET A CG  1 
ATOM 2450 S SD  . MET C 3 142 ? 238.083 341.263 436.818 1.00 82.30  ? 142 MET A SD  1 
ATOM 2451 C CE  . MET C 3 142 ? 238.916 342.333 437.966 1.00 82.30  ? 142 MET A CE  1 
ATOM 2452 N N   . TYR C 3 143 ? 242.686 339.438 436.112 1.00 81.46  ? 143 TYR A N   1 
ATOM 2453 C CA  . TYR C 3 143 ? 243.928 340.174 435.951 1.00 81.46  ? 143 TYR A CA  1 
ATOM 2454 C C   . TYR C 3 143 ? 243.607 341.553 435.408 1.00 81.46  ? 143 TYR A C   1 
ATOM 2455 O O   . TYR C 3 143 ? 242.989 341.670 434.348 1.00 81.46  ? 143 TYR A O   1 
ATOM 2456 C CB  . TYR C 3 143 ? 244.867 339.448 435.000 1.00 81.46  ? 143 TYR A CB  1 
ATOM 2457 C CG  . TYR C 3 143 ? 246.068 340.265 434.639 1.00 81.46  ? 143 TYR A CG  1 
ATOM 2458 C CD1 . TYR C 3 143 ? 246.916 340.730 435.619 1.00 81.46  ? 143 TYR A CD1 1 
ATOM 2459 C CD2 . TYR C 3 143 ? 246.353 340.573 433.324 1.00 81.46  ? 143 TYR A CD2 1 
ATOM 2460 C CE1 . TYR C 3 143 ? 248.010 341.472 435.307 1.00 81.46  ? 143 TYR A CE1 1 
ATOM 2461 C CE2 . TYR C 3 143 ? 247.452 341.318 433.001 1.00 81.46  ? 143 TYR A CE2 1 
ATOM 2462 C CZ  . TYR C 3 143 ? 248.271 341.762 434.004 1.00 81.46  ? 143 TYR A CZ  1 
ATOM 2463 O OH  . TYR C 3 143 ? 249.372 342.507 433.719 1.00 81.46  ? 143 TYR A OH  1 
ATOM 2464 N N   . VAL C 3 144 ? 244.036 342.589 436.111 1.00 82.51  ? 144 VAL A N   1 
ATOM 2465 C CA  . VAL C 3 144 ? 243.785 343.969 435.710 1.00 82.51  ? 144 VAL A CA  1 
ATOM 2466 C C   . VAL C 3 144 ? 245.057 344.516 435.077 1.00 82.51  ? 144 VAL A C   1 
ATOM 2467 O O   . VAL C 3 144 ? 246.107 344.510 435.732 1.00 82.51  ? 144 VAL A O   1 
ATOM 2468 C CB  . VAL C 3 144 ? 243.357 344.830 436.902 1.00 82.51  ? 144 VAL A CB  1 
ATOM 2469 C CG1 . VAL C 3 144 ? 243.211 346.254 436.474 1.00 82.51  ? 144 VAL A CG1 1 
ATOM 2470 C CG2 . VAL C 3 144 ? 242.061 344.329 437.458 1.00 82.51  ? 144 VAL A CG2 1 
ATOM 2471 N N   . PRO C 3 145 ? 245.014 344.993 433.838 1.00 84.47  ? 145 PRO A N   1 
ATOM 2472 C CA  . PRO C 3 145 ? 246.190 345.596 433.217 1.00 84.47  ? 145 PRO A CA  1 
ATOM 2473 C C   . PRO C 3 145 ? 246.516 346.928 433.868 1.00 84.47  ? 145 PRO A C   1 
ATOM 2474 O O   . PRO C 3 145 ? 245.689 347.462 434.621 1.00 84.47  ? 145 PRO A O   1 
ATOM 2475 C CB  . PRO C 3 145 ? 245.748 345.777 431.755 1.00 84.47  ? 145 PRO A CB  1 
ATOM 2476 C CG  . PRO C 3 145 ? 244.616 344.875 431.586 1.00 84.47  ? 145 PRO A CG  1 
ATOM 2477 C CD  . PRO C 3 145 ? 243.911 344.871 432.884 1.00 84.47  ? 145 PRO A CD  1 
ATOM 2478 N N   . PRO C 3 146 ? 247.720 347.493 433.635 1.00 87.17  ? 146 PRO A N   1 
ATOM 2479 C CA  . PRO C 3 146 ? 248.046 348.787 434.246 1.00 87.17  ? 146 PRO A CA  1 
ATOM 2480 C C   . PRO C 3 146 ? 247.183 349.925 433.735 1.00 87.17  ? 146 PRO A C   1 
ATOM 2481 O O   . PRO C 3 146 ? 247.242 350.287 432.559 1.00 87.17  ? 146 PRO A O   1 
ATOM 2482 C CB  . PRO C 3 146 ? 249.513 348.993 433.863 1.00 87.17  ? 146 PRO A CB  1 
ATOM 2483 C CG  . PRO C 3 146 ? 249.727 348.122 432.704 1.00 87.17  ? 146 PRO A CG  1 
ATOM 2484 C CD  . PRO C 3 146 ? 248.901 346.926 432.971 1.00 87.17  ? 146 PRO A CD  1 
ATOM 2485 N N   . GLY C 3 147 ? 246.367 350.487 434.617 1.00 91.99  ? 147 GLY A N   1 
ATOM 2486 C CA  . GLY C 3 147 ? 245.458 351.537 434.219 1.00 91.99  ? 147 GLY A CA  1 
ATOM 2487 C C   . GLY C 3 147 ? 244.117 350.997 433.782 1.00 91.99  ? 147 GLY A C   1 
ATOM 2488 O O   . GLY C 3 147 ? 243.651 351.297 432.682 1.00 91.99  ? 147 GLY A O   1 
ATOM 2489 N N   . GLY C 3 148 ? 243.494 350.187 434.627 1.00 94.97  ? 148 GLY A N   1 
ATOM 2490 C CA  . GLY C 3 148 ? 242.193 349.641 434.338 1.00 94.97  ? 148 GLY A CA  1 
ATOM 2491 C C   . GLY C 3 148 ? 241.251 349.803 435.509 1.00 94.97  ? 148 GLY A C   1 
ATOM 2492 O O   . GLY C 3 148 ? 241.588 350.424 436.520 1.00 94.97  ? 148 GLY A O   1 
ATOM 2493 N N   . PRO C 3 149 ? 240.045 349.255 435.396 1.00 94.79  ? 149 PRO A N   1 
ATOM 2494 C CA  . PRO C 3 149 ? 239.095 349.340 436.509 1.00 94.79  ? 149 PRO A CA  1 
ATOM 2495 C C   . PRO C 3 149 ? 239.471 348.381 437.622 1.00 94.79  ? 149 PRO A C   1 
ATOM 2496 O O   . PRO C 3 149 ? 240.052 347.321 437.384 1.00 94.79  ? 149 PRO A O   1 
ATOM 2497 C CB  . PRO C 3 149 ? 237.764 348.955 435.864 1.00 94.79  ? 149 PRO A CB  1 
ATOM 2498 C CG  . PRO C 3 149 ? 238.153 348.075 434.741 1.00 94.79  ? 149 PRO A CG  1 
ATOM 2499 C CD  . PRO C 3 149 ? 239.458 348.598 434.219 1.00 94.79  ? 149 PRO A CD  1 
ATOM 2500 N N   . VAL C 3 150 ? 239.146 348.770 438.848 1.00 95.90  ? 150 VAL A N   1 
ATOM 2501 C CA  . VAL C 3 150 ? 239.547 348.062 440.056 1.00 95.90  ? 150 VAL A CA  1 
ATOM 2502 C C   . VAL C 3 150 ? 238.300 347.745 440.872 1.00 95.90  ? 150 VAL A C   1 
ATOM 2503 O O   . VAL C 3 150 ? 237.513 348.646 441.166 1.00 95.90  ? 150 VAL A O   1 
ATOM 2504 C CB  . VAL C 3 150 ? 240.541 348.885 440.892 1.00 95.90  ? 150 VAL A CB  1 
ATOM 2505 C CG1 . VAL C 3 150 ? 240.930 348.140 442.124 1.00 95.90  ? 150 VAL A CG1 1 
ATOM 2506 C CG2 . VAL C 3 150 ? 241.788 349.195 440.092 1.00 95.90  ? 150 VAL A CG2 1 
ATOM 2507 N N   . PRO C 3 151 ? 238.076 346.495 441.266 1.00 94.82  ? 151 PRO A N   1 
ATOM 2508 C CA  . PRO C 3 151 ? 236.924 346.181 442.110 1.00 94.82  ? 151 PRO A CA  1 
ATOM 2509 C C   . PRO C 3 151 ? 237.154 346.608 443.545 1.00 94.82  ? 151 PRO A C   1 
ATOM 2510 O O   . PRO C 3 151 ? 238.283 346.814 443.988 1.00 94.82  ? 151 PRO A O   1 
ATOM 2511 C CB  . PRO C 3 151 ? 236.817 344.655 442.016 1.00 94.82  ? 151 PRO A CB  1 
ATOM 2512 C CG  . PRO C 3 151 ? 237.821 344.238 441.019 1.00 94.82  ? 151 PRO A CG  1 
ATOM 2513 C CD  . PRO C 3 151 ? 238.848 345.293 440.945 1.00 94.82  ? 151 PRO A CD  1 
ATOM 2514 N N   . THR C 3 152 ? 236.052 346.738 444.276 1.00 98.92  ? 152 THR A N   1 
ATOM 2515 C CA  . THR C 3 152 ? 236.110 347.083 445.685 1.00 98.92  ? 152 THR A CA  1 
ATOM 2516 C C   . THR C 3 152 ? 235.219 346.229 446.569 1.00 98.92  ? 152 THR A C   1 
ATOM 2517 O O   . THR C 3 152 ? 235.432 346.211 447.783 1.00 98.92  ? 152 THR A O   1 
ATOM 2518 C CB  . THR C 3 152 ? 235.751 348.559 445.893 1.00 98.92  ? 152 THR A CB  1 
ATOM 2519 O OG1 . THR C 3 152 ? 235.879 348.886 447.281 1.00 98.92  ? 152 THR A OG1 1 
ATOM 2520 C CG2 . THR C 3 152 ? 234.340 348.846 445.425 1.00 98.92  ? 152 THR A CG2 1 
ATOM 2521 N N   . LYS C 3 153 ? 234.230 345.544 446.013 1.00 101.86 ? 153 LYS A N   1 
ATOM 2522 C CA  . LYS C 3 153 ? 233.437 344.566 446.736 1.00 101.86 ? 153 LYS A CA  1 
ATOM 2523 C C   . LYS C 3 153 ? 233.423 343.272 445.943 1.00 101.86 ? 153 LYS A C   1 
ATOM 2524 O O   . LYS C 3 153 ? 234.066 343.152 444.901 1.00 101.86 ? 153 LYS A O   1 
ATOM 2525 C CB  . LYS C 3 153 ? 232.006 345.059 446.965 1.00 101.86 ? 153 LYS A CB  1 
ATOM 2526 C CG  . LYS C 3 153 ? 231.906 346.380 447.691 1.00 101.86 ? 153 LYS A CG  1 
ATOM 2527 C CD  . LYS C 3 153 ? 230.577 347.047 447.406 1.00 101.86 ? 153 LYS A CD  1 
ATOM 2528 C CE  . LYS C 3 153 ? 230.398 347.294 445.920 1.00 101.86 ? 153 LYS A CE  1 
ATOM 2529 N NZ  . LYS C 3 153 ? 229.016 347.729 445.600 1.00 101.86 ? 153 LYS A NZ  1 
ATOM 2530 N N   . VAL C 3 154 ? 232.676 342.291 446.444 1.00 102.28 ? 154 VAL A N   1 
ATOM 2531 C CA  . VAL C 3 154 ? 232.567 341.036 445.715 1.00 102.28 ? 154 VAL A CA  1 
ATOM 2532 C C   . VAL C 3 154 ? 231.683 341.209 444.493 1.00 102.28 ? 154 VAL A C   1 
ATOM 2533 O O   . VAL C 3 154 ? 232.116 340.970 443.362 1.00 102.28 ? 154 VAL A O   1 
ATOM 2534 C CB  . VAL C 3 154 ? 232.046 339.924 446.636 1.00 102.28 ? 154 VAL A CB  1 
ATOM 2535 C CG1 . VAL C 3 154 ? 231.860 338.654 445.848 1.00 102.28 ? 154 VAL A CG1 1 
ATOM 2536 C CG2 . VAL C 3 154 ? 233.008 339.704 447.768 1.00 102.28 ? 154 VAL A CG2 1 
ATOM 2537 N N   . LYS C 3 155 ? 230.444 341.642 444.688 1.00 106.34 ? 155 LYS A N   1 
ATOM 2538 C CA  . LYS C 3 155 ? 229.523 341.898 443.585 1.00 106.34 ? 155 LYS A CA  1 
ATOM 2539 C C   . LYS C 3 155 ? 229.757 343.331 443.124 1.00 106.34 ? 155 LYS A C   1 
ATOM 2540 O O   . LYS C 3 155 ? 229.341 344.285 443.784 1.00 106.34 ? 155 LYS A O   1 
ATOM 2541 C CB  . LYS C 3 155 ? 228.079 341.672 444.016 1.00 106.34 ? 155 LYS A CB  1 
ATOM 2542 C CG  . LYS C 3 155 ? 227.053 342.054 442.964 1.00 106.34 ? 155 LYS A CG  1 
ATOM 2543 C CD  . LYS C 3 155 ? 226.685 340.868 442.087 1.00 106.34 ? 155 LYS A CD  1 
ATOM 2544 C CE  . LYS C 3 155 ? 225.371 341.105 441.358 1.00 106.34 ? 155 LYS A CE  1 
ATOM 2545 N NZ  . LYS C 3 155 ? 225.578 341.700 440.008 1.00 106.34 ? 155 LYS A NZ  1 
ATOM 2546 N N   . ASP C 3 156 ? 230.436 343.483 441.990 1.00 104.77 ? 156 ASP A N   1 
ATOM 2547 C CA  . ASP C 3 156 ? 230.844 344.793 441.516 1.00 104.77 ? 156 ASP A CA  1 
ATOM 2548 C C   . ASP C 3 156 ? 230.817 344.791 439.994 1.00 104.77 ? 156 ASP A C   1 
ATOM 2549 O O   . ASP C 3 156 ? 230.749 343.740 439.358 1.00 104.77 ? 156 ASP A O   1 
ATOM 2550 C CB  . ASP C 3 156 ? 232.238 345.145 442.051 1.00 104.77 ? 156 ASP A CB  1 
ATOM 2551 C CG  . ASP C 3 156 ? 232.582 346.604 441.885 1.00 104.77 ? 156 ASP A CG  1 
ATOM 2552 O OD1 . ASP C 3 156 ? 232.082 347.427 442.676 1.00 104.77 ? 156 ASP A OD1 1 
ATOM 2553 O OD2 . ASP C 3 156 ? 233.324 346.930 440.939 1.00 104.77 ? 156 ASP A OD2 1 
ATOM 2554 N N   . TYR C 3 157 ? 230.861 345.989 439.414 1.00 107.28 ? 157 TYR A N   1 
ATOM 2555 C CA  . TYR C 3 157 ? 230.858 346.127 437.965 1.00 107.28 ? 157 TYR A CA  1 
ATOM 2556 C C   . TYR C 3 157 ? 232.184 345.702 437.351 1.00 107.28 ? 157 TYR A C   1 
ATOM 2557 O O   . TYR C 3 157 ? 232.208 345.211 436.219 1.00 107.28 ? 157 TYR A O   1 
ATOM 2558 C CB  . TYR C 3 157 ? 230.539 347.573 437.597 1.00 107.28 ? 157 TYR A CB  1 
ATOM 2559 C CG  . TYR C 3 157 ? 230.847 347.944 436.170 1.00 107.28 ? 157 TYR A CG  1 
ATOM 2560 C CD1 . TYR C 3 157 ? 230.125 347.390 435.120 1.00 107.28 ? 157 TYR A CD1 1 
ATOM 2561 C CD2 . TYR C 3 157 ? 231.857 348.850 435.869 1.00 107.28 ? 157 TYR A CD2 1 
ATOM 2562 C CE1 . TYR C 3 157 ? 230.400 347.726 433.808 1.00 107.28 ? 157 TYR A CE1 1 
ATOM 2563 C CE2 . TYR C 3 157 ? 232.139 349.194 434.561 1.00 107.28 ? 157 TYR A CE2 1 
ATOM 2564 C CZ  . TYR C 3 157 ? 231.408 348.628 433.535 1.00 107.28 ? 157 TYR A CZ  1 
ATOM 2565 O OH  . TYR C 3 157 ? 231.679 348.963 432.228 1.00 107.28 ? 157 TYR A OH  1 
ATOM 2566 N N   . ALA C 3 158 ? 233.284 345.849 438.085 1.00 95.38  ? 158 ALA A N   1 
ATOM 2567 C CA  . ALA C 3 158 ? 234.606 345.622 437.517 1.00 95.38  ? 158 ALA A CA  1 
ATOM 2568 C C   . ALA C 3 158 ? 234.904 344.158 437.238 1.00 95.38  ? 158 ALA A C   1 
ATOM 2569 O O   . ALA C 3 158 ? 235.853 343.874 436.505 1.00 95.38  ? 158 ALA A O   1 
ATOM 2570 C CB  . ALA C 3 158 ? 235.676 346.183 438.446 1.00 95.38  ? 158 ALA A CB  1 
ATOM 2571 N N   . TRP C 3 159 ? 234.135 343.227 437.795 1.00 89.51  ? 159 TRP A N   1 
ATOM 2572 C CA  . TRP C 3 159 ? 234.382 341.822 437.510 1.00 89.51  ? 159 TRP A CA  1 
ATOM 2573 C C   . TRP C 3 159 ? 233.881 341.425 436.134 1.00 89.51  ? 159 TRP A C   1 
ATOM 2574 O O   . TRP C 3 159 ? 234.540 340.646 435.441 1.00 89.51  ? 159 TRP A O   1 
ATOM 2575 C CB  . TRP C 3 159 ? 233.720 340.943 438.565 1.00 89.51  ? 159 TRP A CB  1 
ATOM 2576 C CG  . TRP C 3 159 ? 234.217 341.181 439.933 1.00 89.51  ? 159 TRP A CG  1 
ATOM 2577 C CD1 . TRP C 3 159 ? 233.670 341.994 440.860 1.00 89.51  ? 159 TRP A CD1 1 
ATOM 2578 C CD2 . TRP C 3 159 ? 235.362 340.588 440.544 1.00 89.51  ? 159 TRP A CD2 1 
ATOM 2579 N NE1 . TRP C 3 159 ? 234.401 341.956 442.015 1.00 89.51  ? 159 TRP A NE1 1 
ATOM 2580 C CE2 . TRP C 3 159 ? 235.449 341.097 441.842 1.00 89.51  ? 159 TRP A CE2 1 
ATOM 2581 C CE3 . TRP C 3 159 ? 236.324 339.681 440.114 1.00 89.51  ? 159 TRP A CE3 1 
ATOM 2582 C CZ2 . TRP C 3 159 ? 236.452 340.731 442.712 1.00 89.51  ? 159 TRP A CZ2 1 
ATOM 2583 C CZ3 . TRP C 3 159 ? 237.317 339.320 440.982 1.00 89.51  ? 159 TRP A CZ3 1 
ATOM 2584 C CH2 . TRP C 3 159 ? 237.376 339.840 442.264 1.00 89.51  ? 159 TRP A CH2 1 
ATOM 2585 N N   . GLN C 3 160 ? 232.732 341.945 435.718 1.00 97.20  ? 160 GLN A N   1 
ATOM 2586 C CA  . GLN C 3 160 ? 232.121 341.564 434.457 1.00 97.20  ? 160 GLN A CA  1 
ATOM 2587 C C   . GLN C 3 160 ? 232.528 342.463 433.305 1.00 97.20  ? 160 GLN A C   1 
ATOM 2588 O O   . GLN C 3 160 ? 231.766 342.595 432.345 1.00 97.20  ? 160 GLN A O   1 
ATOM 2589 C CB  . GLN C 3 160 ? 230.600 341.561 434.584 1.00 97.20  ? 160 GLN A CB  1 
ATOM 2590 C CG  . GLN C 3 160 ? 230.048 340.454 435.455 1.00 97.20  ? 160 GLN A CG  1 
ATOM 2591 C CD  . GLN C 3 160 ? 229.690 340.929 436.844 1.00 97.20  ? 160 GLN A CD  1 
ATOM 2592 O OE1 . GLN C 3 160 ? 229.541 342.126 437.082 1.00 97.20  ? 160 GLN A OE1 1 
ATOM 2593 N NE2 . GLN C 3 160 ? 229.538 339.991 437.770 1.00 97.20  ? 160 GLN A NE2 1 
ATOM 2594 N N   . THR C 3 161 ? 233.697 343.090 433.370 1.00 93.54  ? 161 THR A N   1 
ATOM 2595 C CA  . THR C 3 161 ? 234.127 343.937 432.272 1.00 93.54  ? 161 THR A CA  1 
ATOM 2596 C C   . THR C 3 161 ? 234.733 343.083 431.162 1.00 93.54  ? 161 THR A C   1 
ATOM 2597 O O   . THR C 3 161 ? 234.877 341.866 431.284 1.00 93.54  ? 161 THR A O   1 
ATOM 2598 C CB  . THR C 3 161 ? 235.111 344.990 432.757 1.00 93.54  ? 161 THR A CB  1 
ATOM 2599 O OG1 . THR C 3 161 ? 235.383 345.908 431.695 1.00 93.54  ? 161 THR A OG1 1 
ATOM 2600 C CG2 . THR C 3 161 ? 236.386 344.342 433.163 1.00 93.54  ? 161 THR A CG2 1 
ATOM 2601 N N   . SER C 3 162 ? 235.099 343.731 430.062 1.00 93.60  ? 162 SER A N   1 
ATOM 2602 C CA  . SER C 3 162 ? 235.442 343.026 428.837 1.00 93.60  ? 162 SER A CA  1 
ATOM 2603 C C   . SER C 3 162 ? 236.930 342.930 428.564 1.00 93.60  ? 162 SER A C   1 
ATOM 2604 O O   . SER C 3 162 ? 237.366 341.959 427.950 1.00 93.60  ? 162 SER A O   1 
ATOM 2605 C CB  . SER C 3 162 ? 234.771 343.704 427.638 1.00 93.60  ? 162 SER A CB  1 
ATOM 2606 O OG  . SER C 3 162 ? 235.459 343.404 426.442 1.00 93.60  ? 162 SER A OG  1 
ATOM 2607 N N   . THR C 3 163 ? 237.716 343.908 428.991 1.00 91.11  ? 163 THR A N   1 
ATOM 2608 C CA  . THR C 3 163 ? 239.138 343.921 428.692 1.00 91.11  ? 163 THR A CA  1 
ATOM 2609 C C   . THR C 3 163 ? 240.010 343.488 429.860 1.00 91.11  ? 163 THR A C   1 
ATOM 2610 O O   . THR C 3 163 ? 241.207 343.782 429.858 1.00 91.11  ? 163 THR A O   1 
ATOM 2611 C CB  . THR C 3 163 ? 239.564 345.309 428.239 1.00 91.11  ? 163 THR A CB  1 
ATOM 2612 O OG1 . THR C 3 163 ? 240.982 345.324 428.065 1.00 91.11  ? 163 THR A OG1 1 
ATOM 2613 C CG2 . THR C 3 163 ? 239.172 346.333 429.271 1.00 91.11  ? 163 THR A CG2 1 
ATOM 2614 N N   . ASN C 3 164 ? 239.449 342.808 430.855 1.00 84.62  ? 164 ASN A N   1 
ATOM 2615 C CA  . ASN C 3 164 ? 240.248 342.242 431.929 1.00 84.62  ? 164 ASN A CA  1 
ATOM 2616 C C   . ASN C 3 164 ? 240.282 340.737 431.749 1.00 84.62  ? 164 ASN A C   1 
ATOM 2617 O O   . ASN C 3 164 ? 239.291 340.068 432.071 1.00 84.62  ? 164 ASN A O   1 
ATOM 2618 C CB  . ASN C 3 164 ? 239.664 342.595 433.290 1.00 84.62  ? 164 ASN A CB  1 
ATOM 2619 C CG  . ASN C 3 164 ? 239.855 344.044 433.652 1.00 84.62  ? 164 ASN A CG  1 
ATOM 2620 O OD1 . ASN C 3 164 ? 239.375 344.498 434.684 1.00 84.62  ? 164 ASN A OD1 1 
ATOM 2621 N ND2 . ASN C 3 164 ? 240.549 344.781 432.807 1.00 84.62  ? 164 ASN A ND2 1 
ATOM 2622 N N   . PRO C 3 165 ? 241.370 340.160 431.241 1.00 80.53  ? 165 PRO A N   1 
ATOM 2623 C CA  . PRO C 3 165 ? 241.407 338.716 430.973 1.00 80.53  ? 165 PRO A CA  1 
ATOM 2624 C C   . PRO C 3 165 ? 241.459 337.916 432.266 1.00 80.53  ? 165 PRO A C   1 
ATOM 2625 O O   . PRO C 3 165 ? 242.330 338.133 433.107 1.00 80.53  ? 165 PRO A O   1 
ATOM 2626 C CB  . PRO C 3 165 ? 242.691 338.543 430.155 1.00 80.53  ? 165 PRO A CB  1 
ATOM 2627 C CG  . PRO C 3 165 ? 243.505 339.732 430.465 1.00 80.53  ? 165 PRO A CG  1 
ATOM 2628 C CD  . PRO C 3 165 ? 242.567 340.847 430.740 1.00 80.53  ? 165 PRO A CD  1 
ATOM 2629 N N   . SER C 3 166 ? 240.519 336.989 432.421 1.00 75.90  ? 166 SER A N   1 
ATOM 2630 C CA  . SER C 3 166 ? 240.366 336.221 433.645 1.00 75.90  ? 166 SER A CA  1 
ATOM 2631 C C   . SER C 3 166 ? 240.196 334.750 433.315 1.00 75.90  ? 166 SER A C   1 
ATOM 2632 O O   . SER C 3 166 ? 239.742 334.399 432.227 1.00 75.90  ? 166 SER A O   1 
ATOM 2633 C CB  . SER C 3 166 ? 239.164 336.686 434.429 1.00 75.90  ? 166 SER A CB  1 
ATOM 2634 O OG  . SER C 3 166 ? 238.005 336.049 433.942 1.00 75.90  ? 166 SER A OG  1 
ATOM 2635 N N   . VAL C 3 167 ? 240.548 333.892 434.263 1.00 71.43  ? 167 VAL A N   1 
ATOM 2636 C CA  . VAL C 3 167 ? 240.408 332.453 434.085 1.00 71.43  ? 167 VAL A CA  1 
ATOM 2637 C C   . VAL C 3 167 ? 239.355 331.929 435.044 1.00 71.43  ? 167 VAL A C   1 
ATOM 2638 O O   . VAL C 3 167 ? 239.123 332.488 436.116 1.00 71.43  ? 167 VAL A O   1 
ATOM 2639 C CB  . VAL C 3 167 ? 241.748 331.721 434.281 1.00 71.43  ? 167 VAL A CB  1 
ATOM 2640 C CG1 . VAL C 3 167 ? 242.735 332.194 433.267 1.00 71.43  ? 167 VAL A CG1 1 
ATOM 2641 C CG2 . VAL C 3 167 ? 242.291 331.961 435.651 1.00 71.43  ? 167 VAL A CG2 1 
ATOM 2642 N N   . PHE C 3 168 ? 238.695 330.854 434.642 1.00 71.71  ? 168 PHE A N   1 
ATOM 2643 C CA  . PHE C 3 168 ? 237.682 330.197 435.449 1.00 71.71  ? 168 PHE A CA  1 
ATOM 2644 C C   . PHE C 3 168 ? 238.105 328.758 435.671 1.00 71.71  ? 168 PHE A C   1 
ATOM 2645 O O   . PHE C 3 168 ? 238.485 328.068 434.726 1.00 71.71  ? 168 PHE A O   1 
ATOM 2646 C CB  . PHE C 3 168 ? 236.325 330.230 434.772 1.00 71.71  ? 168 PHE A CB  1 
ATOM 2647 C CG  . PHE C 3 168 ? 235.657 331.560 434.823 1.00 71.71  ? 168 PHE A CG  1 
ATOM 2648 C CD1 . PHE C 3 168 ? 235.997 332.551 433.932 1.00 71.71  ? 168 PHE A CD1 1 
ATOM 2649 C CD2 . PHE C 3 168 ? 234.678 331.814 435.755 1.00 71.71  ? 168 PHE A CD2 1 
ATOM 2650 C CE1 . PHE C 3 168 ? 235.380 333.771 433.976 1.00 71.71  ? 168 PHE A CE1 1 
ATOM 2651 C CE2 . PHE C 3 168 ? 234.060 333.032 435.804 1.00 71.71  ? 168 PHE A CE2 1 
ATOM 2652 C CZ  . PHE C 3 168 ? 234.412 334.011 434.913 1.00 71.71  ? 168 PHE A CZ  1 
ATOM 2653 N N   . TRP C 3 169 ? 238.031 328.297 436.910 1.00 78.36  ? 169 TRP A N   1 
ATOM 2654 C CA  . TRP C 3 169 ? 238.651 327.026 437.241 1.00 78.36  ? 169 TRP A CA  1 
ATOM 2655 C C   . TRP C 3 169 ? 237.794 326.270 438.237 1.00 78.36  ? 169 TRP A C   1 
ATOM 2656 O O   . TRP C 3 169 ? 237.520 326.780 439.323 1.00 78.36  ? 169 TRP A O   1 
ATOM 2657 C CB  . TRP C 3 169 ? 240.044 327.263 437.812 1.00 78.36  ? 169 TRP A CB  1 
ATOM 2658 C CG  . TRP C 3 169 ? 240.781 326.035 438.121 1.00 78.36  ? 169 TRP A CG  1 
ATOM 2659 C CD1 . TRP C 3 169 ? 241.397 325.212 437.238 1.00 78.36  ? 169 TRP A CD1 1 
ATOM 2660 C CD2 . TRP C 3 169 ? 241.011 325.484 439.412 1.00 78.36  ? 169 TRP A CD2 1 
ATOM 2661 N NE1 . TRP C 3 169 ? 241.991 324.172 437.897 1.00 78.36  ? 169 TRP A NE1 1 
ATOM 2662 C CE2 . TRP C 3 169 ? 241.768 324.319 439.238 1.00 78.36  ? 169 TRP A CE2 1 
ATOM 2663 C CE3 . TRP C 3 169 ? 240.644 325.859 440.700 1.00 78.36  ? 169 TRP A CE3 1 
ATOM 2664 C CZ2 . TRP C 3 169 ? 242.162 323.527 440.301 1.00 78.36  ? 169 TRP A CZ2 1 
ATOM 2665 C CZ3 . TRP C 3 169 ? 241.038 325.075 441.750 1.00 78.36  ? 169 TRP A CZ3 1 
ATOM 2666 C CH2 . TRP C 3 169 ? 241.788 323.923 441.548 1.00 78.36  ? 169 TRP A CH2 1 
ATOM 2667 N N   . THR C 3 170 ? 237.373 325.067 437.866 1.00 81.59  ? 170 THR A N   1 
ATOM 2668 C CA  . THR C 3 170 ? 236.687 324.170 438.780 1.00 81.59  ? 170 THR A CA  1 
ATOM 2669 C C   . THR C 3 170 ? 237.708 323.394 439.590 1.00 81.59  ? 170 THR A C   1 
ATOM 2670 O O   . THR C 3 170 ? 238.861 323.249 439.193 1.00 81.59  ? 170 THR A O   1 
ATOM 2671 C CB  . THR C 3 170 ? 235.804 323.194 438.022 1.00 81.59  ? 170 THR A CB  1 
ATOM 2672 O OG1 . THR C 3 170 ? 236.535 322.679 436.907 1.00 81.59  ? 170 THR A OG1 1 
ATOM 2673 C CG2 . THR C 3 170 ? 234.566 323.884 437.515 1.00 81.59  ? 170 THR A CG2 1 
ATOM 2674 N N   . GLU C 3 171 ? 237.277 322.883 440.734 1.00 87.88  ? 171 GLU A N   1 
ATOM 2675 C CA  . GLU C 3 171 ? 238.203 322.167 441.595 1.00 87.88  ? 171 GLU A CA  1 
ATOM 2676 C C   . GLU C 3 171 ? 238.290 320.702 441.202 1.00 87.88  ? 171 GLU A C   1 
ATOM 2677 O O   . GLU C 3 171 ? 237.304 320.082 440.803 1.00 87.88  ? 171 GLU A O   1 
ATOM 2678 C CB  . GLU C 3 171 ? 237.786 322.289 443.054 1.00 87.88  ? 171 GLU A CB  1 
ATOM 2679 C CG  . GLU C 3 171 ? 238.325 323.525 443.722 1.00 87.88  ? 171 GLU A CG  1 
ATOM 2680 C CD  . GLU C 3 171 ? 238.124 323.500 445.212 1.00 87.88  ? 171 GLU A CD  1 
ATOM 2681 O OE1 . GLU C 3 171 ? 237.276 324.262 445.716 1.00 87.88  ? 171 GLU A OE1 1 
ATOM 2682 O OE2 . GLU C 3 171 ? 238.813 322.709 445.885 1.00 87.88  ? 171 GLU A OE2 1 
ATOM 2683 N N   . GLY C 3 172 ? 239.488 320.147 441.329 1.00 85.88  ? 172 GLY A N   1 
ATOM 2684 C CA  . GLY C 3 172 ? 239.729 318.778 440.936 1.00 85.88  ? 172 GLY A CA  1 
ATOM 2685 C C   . GLY C 3 172 ? 240.411 318.608 439.601 1.00 85.88  ? 172 GLY A C   1 
ATOM 2686 O O   . GLY C 3 172 ? 240.349 317.517 439.028 1.00 85.88  ? 172 GLY A O   1 
ATOM 2687 N N   . ASN C 3 173 ? 241.064 319.644 439.090 1.00 84.41  ? 173 ASN A N   1 
ATOM 2688 C CA  . ASN C 3 173 ? 241.757 319.564 437.813 1.00 84.41  ? 173 ASN A CA  1 
ATOM 2689 C C   . ASN C 3 173 ? 243.188 320.046 437.980 1.00 84.41  ? 173 ASN A C   1 
ATOM 2690 O O   . ASN C 3 173 ? 243.649 320.239 439.106 1.00 84.41  ? 173 ASN A O   1 
ATOM 2691 C CB  . ASN C 3 173 ? 241.039 320.396 436.757 1.00 84.41  ? 173 ASN A CB  1 
ATOM 2692 C CG  . ASN C 3 173 ? 239.634 319.923 436.504 1.00 84.41  ? 173 ASN A CG  1 
ATOM 2693 O OD1 . ASN C 3 173 ? 239.393 319.113 435.618 1.00 84.41  ? 173 ASN A OD1 1 
ATOM 2694 N ND2 . ASN C 3 173 ? 238.692 320.432 437.280 1.00 84.41  ? 173 ASN A ND2 1 
ATOM 2695 N N   . ALA C 3 174 ? 243.900 320.229 436.875 1.00 81.44  ? 174 ALA A N   1 
ATOM 2696 C CA  . ALA C 3 174 ? 245.233 320.794 436.943 1.00 81.44  ? 174 ALA A CA  1 
ATOM 2697 C C   . ALA C 3 174 ? 245.155 322.272 437.322 1.00 81.44  ? 174 ALA A C   1 
ATOM 2698 O O   . ALA C 3 174 ? 244.166 322.941 437.019 1.00 81.44  ? 174 ALA A O   1 
ATOM 2699 C CB  . ALA C 3 174 ? 245.943 320.626 435.607 1.00 81.44  ? 174 ALA A CB  1 
ATOM 2700 N N   . PRO C 3 175 ? 246.172 322.796 438.012 1.00 78.15  ? 175 PRO A N   1 
ATOM 2701 C CA  . PRO C 3 175 ? 246.103 324.179 438.480 1.00 78.15  ? 175 PRO A CA  1 
ATOM 2702 C C   . PRO C 3 175 ? 246.232 325.171 437.338 1.00 78.15  ? 175 PRO A C   1 
ATOM 2703 O O   . PRO C 3 175 ? 246.931 324.913 436.345 1.00 78.15  ? 175 PRO A O   1 
ATOM 2704 C CB  . PRO C 3 175 ? 247.291 324.280 439.451 1.00 78.15  ? 175 PRO A CB  1 
ATOM 2705 C CG  . PRO C 3 175 ? 248.106 323.094 439.195 1.00 78.15  ? 175 PRO A CG  1 
ATOM 2706 C CD  . PRO C 3 175 ? 247.183 322.038 438.757 1.00 78.15  ? 175 PRO A CD  1 
ATOM 2707 N N   . PRO C 3 176 ? 245.581 326.338 437.444 1.00 76.98  ? 176 PRO A N   1 
ATOM 2708 C CA  . PRO C 3 176 ? 245.394 327.219 436.282 1.00 76.98  ? 176 PRO A CA  1 
ATOM 2709 C C   . PRO C 3 176 ? 246.549 328.142 435.925 1.00 76.98  ? 176 PRO A C   1 
ATOM 2710 O O   . PRO C 3 176 ? 246.628 329.267 436.417 1.00 76.98  ? 176 PRO A O   1 
ATOM 2711 C CB  . PRO C 3 176 ? 244.164 328.035 436.679 1.00 76.98  ? 176 PRO A CB  1 
ATOM 2712 C CG  . PRO C 3 176 ? 244.179 328.053 438.135 1.00 76.98  ? 176 PRO A CG  1 
ATOM 2713 C CD  . PRO C 3 176 ? 244.776 326.775 438.592 1.00 76.98  ? 176 PRO A CD  1 
ATOM 2714 N N   . ARG C 3 177 ? 247.447 327.685 435.068 1.00 81.65  ? 177 ARG A N   1 
ATOM 2715 C CA  . ARG C 3 177 ? 248.530 328.524 434.578 1.00 81.65  ? 177 ARG A CA  1 
ATOM 2716 C C   . ARG C 3 177 ? 248.017 329.599 433.625 1.00 81.65  ? 177 ARG A C   1 
ATOM 2717 O O   . ARG C 3 177 ? 247.065 329.388 432.875 1.00 81.65  ? 177 ARG A O   1 
ATOM 2718 C CB  . ARG C 3 177 ? 249.554 327.654 433.866 1.00 81.65  ? 177 ARG A CB  1 
ATOM 2719 C CG  . ARG C 3 177 ? 250.894 328.271 433.638 1.00 81.65  ? 177 ARG A CG  1 
ATOM 2720 C CD  . ARG C 3 177 ? 251.705 327.363 432.760 1.00 81.65  ? 177 ARG A CD  1 
ATOM 2721 N NE  . ARG C 3 177 ? 252.083 326.146 433.458 1.00 81.65  ? 177 ARG A NE  1 
ATOM 2722 C CZ  . ARG C 3 177 ? 253.215 326.009 434.131 1.00 81.65  ? 177 ARG A CZ  1 
ATOM 2723 N NH1 . ARG C 3 177 ? 254.068 327.016 434.191 1.00 81.65  ? 177 ARG A NH1 1 
ATOM 2724 N NH2 . ARG C 3 177 ? 253.496 324.871 434.741 1.00 81.65  ? 177 ARG A NH2 1 
ATOM 2725 N N   . MET C 3 178 ? 248.659 330.765 433.667 1.00 86.29  ? 178 MET A N   1 
ATOM 2726 C CA  . MET C 3 178 ? 248.467 331.809 432.666 1.00 86.29  ? 178 MET A CA  1 
ATOM 2727 C C   . MET C 3 178 ? 249.773 332.573 432.533 1.00 86.29  ? 178 MET A C   1 
ATOM 2728 O O   . MET C 3 178 ? 250.641 332.499 433.402 1.00 86.29  ? 178 MET A O   1 
ATOM 2729 C CB  . MET C 3 178 ? 247.318 332.749 433.027 1.00 86.29  ? 178 MET A CB  1 
ATOM 2730 C CG  . MET C 3 178 ? 247.687 333.831 434.006 1.00 86.29  ? 178 MET A CG  1 
ATOM 2731 S SD  . MET C 3 178 ? 246.253 334.579 434.793 1.00 86.29  ? 178 MET A SD  1 
ATOM 2732 C CE  . MET C 3 178 ? 245.413 335.261 433.375 1.00 86.29  ? 178 MET A CE  1 
ATOM 2733 N N   . SER C 3 179 ? 249.912 333.304 431.432 1.00 90.90  ? 179 SER A N   1 
ATOM 2734 C CA  . SER C 3 179 ? 251.184 333.922 431.076 1.00 90.90  ? 179 SER A CA  1 
ATOM 2735 C C   . SER C 3 179 ? 250.997 335.369 430.667 1.00 90.90  ? 179 SER A C   1 
ATOM 2736 O O   . SER C 3 179 ? 250.185 335.670 429.792 1.00 90.90  ? 179 SER A O   1 
ATOM 2737 C CB  . SER C 3 179 ? 251.851 333.178 429.934 1.00 90.90  ? 179 SER A CB  1 
ATOM 2738 O OG  . SER C 3 179 ? 253.020 333.856 429.525 1.00 90.90  ? 179 SER A OG  1 
ATOM 2739 N N   . ILE C 3 180 ? 251.795 336.247 431.250 1.00 85.72  ? 180 ILE A N   1 
ATOM 2740 C CA  . ILE C 3 180 ? 251.712 337.687 431.029 1.00 85.72  ? 180 ILE A CA  1 
ATOM 2741 C C   . ILE C 3 180 ? 252.931 338.110 430.223 1.00 85.72  ? 180 ILE A C   1 
ATOM 2742 O O   . ILE C 3 180 ? 254.058 337.818 430.634 1.00 85.72  ? 180 ILE A O   1 
ATOM 2743 C CB  . ILE C 3 180 ? 251.654 338.452 432.360 1.00 85.72  ? 180 ILE A CB  1 
ATOM 2744 C CG1 . ILE C 3 180 ? 250.407 338.046 433.131 1.00 85.72  ? 180 ILE A CG1 1 
ATOM 2745 C CG2 . ILE C 3 180 ? 251.687 339.935 432.131 1.00 85.72  ? 180 ILE A CG2 1 
ATOM 2746 C CD1 . ILE C 3 180 ? 250.306 338.677 434.478 1.00 85.72  ? 180 ILE A CD1 1 
ATOM 2747 N N   . PRO C 3 181 ? 252.765 338.793 429.102 1.00 87.24  ? 181 PRO A N   1 
ATOM 2748 C CA  . PRO C 3 181 ? 253.915 339.233 428.315 1.00 87.24  ? 181 PRO A CA  1 
ATOM 2749 C C   . PRO C 3 181 ? 254.538 340.476 428.937 1.00 87.24  ? 181 PRO A C   1 
ATOM 2750 O O   . PRO C 3 181 ? 254.097 340.974 429.966 1.00 87.24  ? 181 PRO A O   1 
ATOM 2751 C CB  . PRO C 3 181 ? 253.300 339.537 426.958 1.00 87.24  ? 181 PRO A CB  1 
ATOM 2752 C CG  . PRO C 3 181 ? 251.953 340.007 427.296 1.00 87.24  ? 181 PRO A CG  1 
ATOM 2753 C CD  . PRO C 3 181 ? 251.500 339.212 428.485 1.00 87.24  ? 181 PRO A CD  1 
ATOM 2754 N N   . PHE C 3 182 ? 255.577 340.980 428.283 1.00 85.80  ? 182 PHE A N   1 
ATOM 2755 C CA  . PHE C 3 182 ? 256.346 342.104 428.809 1.00 85.80  ? 182 PHE A CA  1 
ATOM 2756 C C   . PHE C 3 182 ? 255.593 343.392 428.519 1.00 85.80  ? 182 PHE A C   1 
ATOM 2757 O O   . PHE C 3 182 ? 255.650 343.922 427.412 1.00 85.80  ? 182 PHE A O   1 
ATOM 2758 C CB  . PHE C 3 182 ? 257.734 342.122 428.188 1.00 85.80  ? 182 PHE A CB  1 
ATOM 2759 C CG  . PHE C 3 182 ? 258.511 343.359 428.483 1.00 85.80  ? 182 PHE A CG  1 
ATOM 2760 C CD1 . PHE C 3 182 ? 258.772 343.732 429.781 1.00 85.80  ? 182 PHE A CD1 1 
ATOM 2761 C CD2 . PHE C 3 182 ? 258.991 344.142 427.458 1.00 85.80  ? 182 PHE A CD2 1 
ATOM 2762 C CE1 . PHE C 3 182 ? 259.487 344.866 430.051 1.00 85.80  ? 182 PHE A CE1 1 
ATOM 2763 C CE2 . PHE C 3 182 ? 259.706 345.274 427.722 1.00 85.80  ? 182 PHE A CE2 1 
ATOM 2764 C CZ  . PHE C 3 182 ? 259.955 345.637 429.018 1.00 85.80  ? 182 PHE A CZ  1 
ATOM 2765 N N   . ILE C 3 183 ? 254.892 343.919 429.514 1.00 89.09  ? 183 ILE A N   1 
ATOM 2766 C CA  . ILE C 3 183 ? 254.074 345.109 429.332 1.00 89.09  ? 183 ILE A CA  1 
ATOM 2767 C C   . ILE C 3 183 ? 254.766 346.297 429.990 1.00 89.09  ? 183 ILE A C   1 
ATOM 2768 O O   . ILE C 3 183 ? 254.879 346.382 431.218 1.00 89.09  ? 183 ILE A O   1 
ATOM 2769 C CB  . ILE C 3 183 ? 252.642 344.899 429.842 1.00 89.09  ? 183 ILE A CB  1 
ATOM 2770 C CG1 . ILE C 3 183 ? 252.604 344.252 431.216 1.00 89.09  ? 183 ILE A CG1 1 
ATOM 2771 C CG2 . ILE C 3 183 ? 251.892 343.996 428.913 1.00 89.09  ? 183 ILE A CG2 1 
ATOM 2772 C CD1 . ILE C 3 183 ? 251.267 344.298 431.810 1.00 89.09  ? 183 ILE A CD1 1 
ATOM 2773 N N   . SER C 3 184 ? 255.259 347.209 429.159 1.00 91.02  ? 184 SER A N   1 
ATOM 2774 C CA  . SER C 3 184 ? 255.863 348.453 429.608 1.00 91.02  ? 184 SER A CA  1 
ATOM 2775 C C   . SER C 3 184 ? 255.945 349.390 428.418 1.00 91.02  ? 184 SER A C   1 
ATOM 2776 O O   . SER C 3 184 ? 255.924 348.957 427.264 1.00 91.02  ? 184 SER A O   1 
ATOM 2777 C CB  . SER C 3 184 ? 257.260 348.246 430.195 1.00 91.02  ? 184 SER A CB  1 
ATOM 2778 O OG  . SER C 3 184 ? 257.830 349.484 430.566 1.00 91.02  ? 184 SER A OG  1 
ATOM 2779 N N   . ILE C 3 185 ? 256.042 350.678 428.713 1.00 91.18  ? 185 ILE A N   1 
ATOM 2780 C CA  . ILE C 3 185 ? 256.335 351.654 427.676 1.00 91.18  ? 185 ILE A CA  1 
ATOM 2781 C C   . ILE C 3 185 ? 257.824 351.682 427.374 1.00 91.18  ? 185 ILE A C   1 
ATOM 2782 O O   . ILE C 3 185 ? 258.228 351.733 426.210 1.00 91.18  ? 185 ILE A O   1 
ATOM 2783 C CB  . ILE C 3 185 ? 255.813 353.040 428.096 1.00 91.18  ? 185 ILE A CB  1 
ATOM 2784 C CG1 . ILE C 3 185 ? 254.326 352.981 428.431 1.00 91.18  ? 185 ILE A CG1 1 
ATOM 2785 C CG2 . ILE C 3 185 ? 256.018 354.043 426.988 1.00 91.18  ? 185 ILE A CG2 1 
ATOM 2786 C CD1 . ILE C 3 185 ? 253.466 352.353 427.350 1.00 91.18  ? 185 ILE A CD1 1 
ATOM 2787 N N   . GLY C 3 186 ? 258.655 351.619 428.405 1.00 90.27  ? 186 GLY A N   1 
ATOM 2788 C CA  . GLY C 3 186 ? 260.085 351.588 428.207 1.00 90.27  ? 186 GLY A CA  1 
ATOM 2789 C C   . GLY C 3 186 ? 260.554 350.241 427.708 1.00 90.27  ? 186 GLY A C   1 
ATOM 2790 O O   . GLY C 3 186 ? 259.826 349.252 427.696 1.00 90.27  ? 186 GLY A O   1 
ATOM 2791 N N   . ASN C 3 187 ? 261.812 350.203 427.291 1.00 92.11  ? 187 ASN A N   1 
ATOM 2792 C CA  . ASN C 3 187 ? 262.379 349.009 426.687 1.00 92.11  ? 187 ASN A CA  1 
ATOM 2793 C C   . ASN C 3 187 ? 262.839 347.978 427.701 1.00 92.11  ? 187 ASN A C   1 
ATOM 2794 O O   . ASN C 3 187 ? 263.192 346.866 427.305 1.00 92.11  ? 187 ASN A O   1 
ATOM 2795 C CB  . ASN C 3 187 ? 263.546 349.395 425.788 1.00 92.11  ? 187 ASN A CB  1 
ATOM 2796 C CG  . ASN C 3 187 ? 263.206 350.528 424.866 1.00 92.11  ? 187 ASN A CG  1 
ATOM 2797 O OD1 . ASN C 3 187 ? 263.259 351.688 425.253 1.00 92.11  ? 187 ASN A OD1 1 
ATOM 2798 N ND2 . ASN C 3 187 ? 262.858 350.205 423.633 1.00 92.11  ? 187 ASN A ND2 1 
ATOM 2799 N N   . ALA C 3 188 ? 262.840 348.307 428.988 1.00 85.23  ? 188 ALA A N   1 
ATOM 2800 C CA  . ALA C 3 188 ? 263.279 347.369 430.008 1.00 85.23  ? 188 ALA A CA  1 
ATOM 2801 C C   . ALA C 3 188 ? 262.706 347.790 431.347 1.00 85.23  ? 188 ALA A C   1 
ATOM 2802 O O   . ALA C 3 188 ? 262.474 348.973 431.596 1.00 85.23  ? 188 ALA A O   1 
ATOM 2803 C CB  . ALA C 3 188 ? 264.804 347.304 430.092 1.00 85.23  ? 188 ALA A CB  1 
ATOM 2804 N N   . TYR C 3 189 ? 262.481 346.804 432.208 1.00 85.07  ? 189 TYR A N   1 
ATOM 2805 C CA  . TYR C 3 189 ? 262.134 347.100 433.585 1.00 85.07  ? 189 TYR A CA  1 
ATOM 2806 C C   . TYR C 3 189 ? 263.326 347.725 434.284 1.00 85.07  ? 189 TYR A C   1 
ATOM 2807 O O   . TYR C 3 189 ? 264.474 347.537 433.890 1.00 85.07  ? 189 TYR A O   1 
ATOM 2808 C CB  . TYR C 3 189 ? 261.726 345.837 434.333 1.00 85.07  ? 189 TYR A CB  1 
ATOM 2809 C CG  . TYR C 3 189 ? 260.417 345.236 433.905 1.00 85.07  ? 189 TYR A CG  1 
ATOM 2810 C CD1 . TYR C 3 189 ? 259.285 346.010 433.777 1.00 85.07  ? 189 TYR A CD1 1 
ATOM 2811 C CD2 . TYR C 3 189 ? 260.313 343.885 433.649 1.00 85.07  ? 189 TYR A CD2 1 
ATOM 2812 C CE1 . TYR C 3 189 ? 258.090 345.461 433.398 1.00 85.07  ? 189 TYR A CE1 1 
ATOM 2813 C CE2 . TYR C 3 189 ? 259.124 343.327 433.270 1.00 85.07  ? 189 TYR A CE2 1 
ATOM 2814 C CZ  . TYR C 3 189 ? 258.018 344.119 433.147 1.00 85.07  ? 189 TYR A CZ  1 
ATOM 2815 O OH  . TYR C 3 189 ? 256.830 343.554 432.767 1.00 85.07  ? 189 TYR A OH  1 
ATOM 2816 N N   . SER C 3 190 ? 263.051 348.477 435.339 1.00 88.10  ? 190 SER A N   1 
ATOM 2817 C CA  . SER C 3 190 ? 264.099 349.180 436.065 1.00 88.10  ? 190 SER A CA  1 
ATOM 2818 C C   . SER C 3 190 ? 264.033 348.770 437.522 1.00 88.10  ? 190 SER A C   1 
ATOM 2819 O O   . SER C 3 190 ? 263.070 349.098 438.218 1.00 88.10  ? 190 SER A O   1 
ATOM 2820 C CB  . SER C 3 190 ? 263.949 350.689 435.927 1.00 88.10  ? 190 SER A CB  1 
ATOM 2821 O OG  . SER C 3 190 ? 264.624 351.341 436.980 1.00 88.10  ? 190 SER A OG  1 
ATOM 2822 N N   . CYS C 3 191 ? 265.055 348.064 437.986 1.00 90.98  ? 191 CYS A N   1 
ATOM 2823 C CA  . CYS C 3 191 ? 265.071 347.641 439.375 1.00 90.98  ? 191 CYS A CA  1 
ATOM 2824 C C   . CYS C 3 191 ? 265.448 348.766 440.326 1.00 90.98  ? 191 CYS A C   1 
ATOM 2825 O O   . CYS C 3 191 ? 265.172 348.662 441.523 1.00 90.98  ? 191 CYS A O   1 
ATOM 2826 C CB  . CYS C 3 191 ? 266.026 346.468 439.544 1.00 90.98  ? 191 CYS A CB  1 
ATOM 2827 S SG  . CYS C 3 191 ? 265.440 344.961 438.762 1.00 90.98  ? 191 CYS A SG  1 
ATOM 2828 N N   . PHE C 3 192 ? 266.063 349.833 439.828 1.00 92.61  ? 192 PHE A N   1 
ATOM 2829 C CA  . PHE C 3 192 ? 266.401 350.986 440.645 1.00 92.61  ? 192 PHE A CA  1 
ATOM 2830 C C   . PHE C 3 192 ? 266.041 352.252 439.891 1.00 92.61  ? 192 PHE A C   1 
ATOM 2831 O O   . PHE C 3 192 ? 265.967 352.258 438.663 1.00 92.61  ? 192 PHE A O   1 
ATOM 2832 C CB  . PHE C 3 192 ? 267.877 351.012 441.001 1.00 92.61  ? 192 PHE A CB  1 
ATOM 2833 C CG  . PHE C 3 192 ? 268.250 350.040 442.057 1.00 92.61  ? 192 PHE A CG  1 
ATOM 2834 C CD1 . PHE C 3 192 ? 268.606 348.753 441.729 1.00 92.61  ? 192 PHE A CD1 1 
ATOM 2835 C CD2 . PHE C 3 192 ? 268.240 350.411 443.383 1.00 92.61  ? 192 PHE A CD2 1 
ATOM 2836 C CE1 . PHE C 3 192 ? 268.950 347.859 442.704 1.00 92.61  ? 192 PHE A CE1 1 
ATOM 2837 C CE2 . PHE C 3 192 ? 268.584 349.515 444.365 1.00 92.61  ? 192 PHE A CE2 1 
ATOM 2838 C CZ  . PHE C 3 192 ? 268.938 348.237 444.023 1.00 92.61  ? 192 PHE A CZ  1 
ATOM 2839 N N   . TYR C 3 193 ? 265.826 353.329 440.637 1.00 95.17  ? 193 TYR A N   1 
ATOM 2840 C CA  . TYR C 3 193 ? 265.427 354.592 440.028 1.00 95.17  ? 193 TYR A CA  1 
ATOM 2841 C C   . TYR C 3 193 ? 265.874 355.717 440.944 1.00 95.17  ? 193 TYR A C   1 
ATOM 2842 O O   . TYR C 3 193 ? 265.284 355.918 442.005 1.00 95.17  ? 193 TYR A O   1 
ATOM 2843 C CB  . TYR C 3 193 ? 263.926 354.632 439.814 1.00 95.17  ? 193 TYR A CB  1 
ATOM 2844 C CG  . TYR C 3 193 ? 263.450 355.770 438.957 1.00 95.17  ? 193 TYR A CG  1 
ATOM 2845 C CD1 . TYR C 3 193 ? 263.544 355.710 437.580 1.00 95.17  ? 193 TYR A CD1 1 
ATOM 2846 C CD2 . TYR C 3 193 ? 262.882 356.895 439.525 1.00 95.17  ? 193 TYR A CD2 1 
ATOM 2847 C CE1 . TYR C 3 193 ? 263.099 356.743 436.793 1.00 95.17  ? 193 TYR A CE1 1 
ATOM 2848 C CE2 . TYR C 3 193 ? 262.436 357.935 438.747 1.00 95.17  ? 193 TYR A CE2 1 
ATOM 2849 C CZ  . TYR C 3 193 ? 262.546 357.852 437.383 1.00 95.17  ? 193 TYR A CZ  1 
ATOM 2850 O OH  . TYR C 3 193 ? 262.100 358.887 436.599 1.00 95.17  ? 193 TYR A OH  1 
ATOM 2851 N N   . ASP C 3 194 ? 266.909 356.443 440.540 1.00 94.80  ? 194 ASP A N   1 
ATOM 2852 C CA  . ASP C 3 194 ? 267.388 357.598 441.290 1.00 94.80  ? 194 ASP A CA  1 
ATOM 2853 C C   . ASP C 3 194 ? 266.741 358.830 440.684 1.00 94.80  ? 194 ASP A C   1 
ATOM 2854 O O   . ASP C 3 194 ? 267.315 359.496 439.825 1.00 94.80  ? 194 ASP A O   1 
ATOM 2855 C CB  . ASP C 3 194 ? 268.902 357.699 441.257 1.00 94.80  ? 194 ASP A CB  1 
ATOM 2856 C CG  . ASP C 3 194 ? 269.417 358.859 442.073 1.00 94.80  ? 194 ASP A CG  1 
ATOM 2857 O OD1 . ASP C 3 194 ? 268.716 359.283 443.012 1.00 94.80  ? 194 ASP A OD1 1 
ATOM 2858 O OD2 . ASP C 3 194 ? 270.522 359.352 441.776 1.00 94.80  ? 194 ASP A OD2 1 
ATOM 2859 N N   . GLY C 3 195 ? 265.541 359.136 441.138 1.00 94.70  ? 195 GLY A N   1 
ATOM 2860 C CA  . GLY C 3 195 ? 264.827 360.278 440.615 1.00 94.70  ? 195 GLY A CA  1 
ATOM 2861 C C   . GLY C 3 195 ? 263.416 360.281 441.130 1.00 94.70  ? 195 GLY A C   1 
ATOM 2862 O O   . GLY C 3 195 ? 262.905 359.282 441.633 1.00 94.70  ? 195 GLY A O   1 
ATOM 2863 N N   . TRP C 3 196 ? 262.785 361.430 440.996 1.00 97.52  ? 196 TRP A N   1 
ATOM 2864 C CA  . TRP C 3 196 ? 261.449 361.604 441.523 1.00 97.52  ? 196 TRP A CA  1 
ATOM 2865 C C   . TRP C 3 196 ? 260.434 361.078 440.521 1.00 97.52  ? 196 TRP A C   1 
ATOM 2866 O O   . TRP C 3 196 ? 260.780 360.614 439.437 1.00 97.52  ? 196 TRP A O   1 
ATOM 2867 C CB  . TRP C 3 196 ? 261.212 363.068 441.869 1.00 97.52  ? 196 TRP A CB  1 
ATOM 2868 C CG  . TRP C 3 196 ? 261.971 363.462 443.083 1.00 97.52  ? 196 TRP A CG  1 
ATOM 2869 C CD1 . TRP C 3 196 ? 261.495 363.531 444.351 1.00 97.52  ? 196 TRP A CD1 1 
ATOM 2870 C CD2 . TRP C 3 196 ? 263.356 363.805 443.157 1.00 97.52  ? 196 TRP A CD2 1 
ATOM 2871 N NE1 . TRP C 3 196 ? 262.489 363.910 445.212 1.00 97.52  ? 196 TRP A NE1 1 
ATOM 2872 C CE2 . TRP C 3 196 ? 263.643 364.084 444.500 1.00 97.52  ? 196 TRP A CE2 1 
ATOM 2873 C CE3 . TRP C 3 196 ? 264.379 363.916 442.216 1.00 97.52  ? 196 TRP A CE3 1 
ATOM 2874 C CZ2 . TRP C 3 196 ? 264.906 364.459 444.924 1.00 97.52  ? 196 TRP A CZ2 1 
ATOM 2875 C CZ3 . TRP C 3 196 ? 265.630 364.286 442.638 1.00 97.52  ? 196 TRP A CZ3 1 
ATOM 2876 C CH2 . TRP C 3 196 ? 265.885 364.554 443.979 1.00 97.52  ? 196 TRP A CH2 1 
ATOM 2877 N N   . THR C 3 197 ? 259.168 361.129 440.904 1.00 97.76  ? 197 THR A N   1 
ATOM 2878 C CA  . THR C 3 197 ? 258.125 360.548 440.077 1.00 97.76  ? 197 THR A CA  1 
ATOM 2879 C C   . THR C 3 197 ? 257.789 361.448 438.901 1.00 97.76  ? 197 THR A C   1 
ATOM 2880 O O   . THR C 3 197 ? 257.283 360.986 437.882 1.00 97.76  ? 197 THR A O   1 
ATOM 2881 C CB  . THR C 3 197 ? 256.863 360.299 440.877 1.00 97.76  ? 197 THR A CB  1 
ATOM 2882 O OG1 . THR C 3 197 ? 255.906 359.638 440.047 1.00 97.76  ? 197 THR A OG1 1 
ATOM 2883 C CG2 . THR C 3 197 ? 256.286 361.616 441.337 1.00 97.76  ? 197 THR A CG2 1 
ATOM 2884 N N   . VAL C 3 204 ? 257.485 362.436 445.183 1.00 96.08  ? 204 VAL A N   1 
ATOM 2885 C CA  . VAL C 3 204 ? 257.911 361.236 445.888 1.00 96.08  ? 204 VAL A CA  1 
ATOM 2886 C C   . VAL C 3 204 ? 259.164 360.669 445.213 1.00 96.08  ? 204 VAL A C   1 
ATOM 2887 O O   . VAL C 3 204 ? 259.297 360.704 443.992 1.00 96.08  ? 204 VAL A O   1 
ATOM 2888 C CB  . VAL C 3 204 ? 256.744 360.220 445.978 1.00 96.08  ? 204 VAL A CB  1 
ATOM 2889 C CG1 . VAL C 3 204 ? 256.265 359.799 444.610 1.00 96.08  ? 204 VAL A CG1 1 
ATOM 2890 C CG2 . VAL C 3 204 ? 257.120 359.014 446.817 1.00 96.08  ? 204 VAL A CG2 1 
ATOM 2891 N N   . TYR C 3 205 ? 260.108 360.198 446.022 1.00 93.47  ? 205 TYR A N   1 
ATOM 2892 C CA  . TYR C 3 205 ? 261.441 359.853 445.549 1.00 93.47  ? 205 TYR A CA  1 
ATOM 2893 C C   . TYR C 3 205 ? 261.584 358.354 445.347 1.00 93.47  ? 205 TYR A C   1 
ATOM 2894 O O   . TYR C 3 205 ? 261.260 357.569 446.238 1.00 93.47  ? 205 TYR A O   1 
ATOM 2895 C CB  . TYR C 3 205 ? 262.487 360.340 446.543 1.00 93.47  ? 205 TYR A CB  1 
ATOM 2896 C CG  . TYR C 3 205 ? 263.871 359.817 446.284 1.00 93.47  ? 205 TYR A CG  1 
ATOM 2897 C CD1 . TYR C 3 205 ? 264.573 360.194 445.157 1.00 93.47  ? 205 TYR A CD1 1 
ATOM 2898 C CD2 . TYR C 3 205 ? 264.483 358.960 447.177 1.00 93.47  ? 205 TYR A CD2 1 
ATOM 2899 C CE1 . TYR C 3 205 ? 265.839 359.727 444.924 1.00 93.47  ? 205 TYR A CE1 1 
ATOM 2900 C CE2 . TYR C 3 205 ? 265.746 358.489 446.951 1.00 93.47  ? 205 TYR A CE2 1 
ATOM 2901 C CZ  . TYR C 3 205 ? 266.418 358.876 445.824 1.00 93.47  ? 205 TYR A CZ  1 
ATOM 2902 O OH  . TYR C 3 205 ? 267.683 358.405 445.592 1.00 93.47  ? 205 TYR A OH  1 
ATOM 2903 N N   . GLY C 3 206 ? 262.087 357.968 444.182 1.00 93.48  ? 206 GLY A N   1 
ATOM 2904 C CA  . GLY C 3 206 ? 262.393 356.583 443.898 1.00 93.48  ? 206 GLY A CA  1 
ATOM 2905 C C   . GLY C 3 206 ? 261.176 355.702 443.752 1.00 93.48  ? 206 GLY A C   1 
ATOM 2906 O O   . GLY C 3 206 ? 260.995 354.764 444.526 1.00 93.48  ? 206 GLY A O   1 
ATOM 2907 N N   . ILE C 3 207 ? 260.335 355.983 442.761 1.00 92.27  ? 207 ILE A N   1 
ATOM 2908 C CA  . ILE C 3 207 ? 259.094 355.253 442.547 1.00 92.27  ? 207 ILE A CA  1 
ATOM 2909 C C   . ILE C 3 207 ? 259.062 354.591 441.177 1.00 92.27  ? 207 ILE A C   1 
ATOM 2910 O O   . ILE C 3 207 ? 258.760 353.396 441.066 1.00 92.27  ? 207 ILE A O   1 
ATOM 2911 C CB  . ILE C 3 207 ? 257.866 356.164 442.754 1.00 92.27  ? 207 ILE A CB  1 
ATOM 2912 C CG1 . ILE C 3 207 ? 257.635 356.359 444.246 1.00 92.27  ? 207 ILE A CG1 1 
ATOM 2913 C CG2 . ILE C 3 207 ? 256.620 355.585 442.125 1.00 92.27  ? 207 ILE A CG2 1 
ATOM 2914 C CD1 . ILE C 3 207 ? 257.348 355.075 444.982 1.00 92.27  ? 207 ILE A CD1 1 
ATOM 2915 N N   . ASN C 3 208 ? 259.397 355.350 440.124 1.00 94.83  ? 208 ASN A N   1 
ATOM 2916 C CA  . ASN C 3 208 ? 259.451 354.883 438.738 1.00 94.83  ? 208 ASN A CA  1 
ATOM 2917 C C   . ASN C 3 208 ? 258.121 354.322 438.270 1.00 94.83  ? 208 ASN A C   1 
ATOM 2918 O O   . ASN C 3 208 ? 257.956 353.107 438.199 1.00 94.83  ? 208 ASN A O   1 
ATOM 2919 C CB  . ASN C 3 208 ? 260.550 353.842 438.511 1.00 94.83  ? 208 ASN A CB  1 
ATOM 2920 C CG  . ASN C 3 208 ? 260.796 353.579 437.044 1.00 94.83  ? 208 ASN A CG  1 
ATOM 2921 O OD1 . ASN C 3 208 ? 260.761 354.493 436.225 1.00 94.83  ? 208 ASN A OD1 1 
ATOM 2922 N ND2 . ASN C 3 208 ? 261.037 352.323 436.703 1.00 94.83  ? 208 ASN A ND2 1 
ATOM 2923 N N   . THR C 3 209 ? 257.143 355.180 438.006 1.00 94.79  ? 209 THR A N   1 
ATOM 2924 C CA  . THR C 3 209 ? 255.815 354.738 437.589 1.00 94.79  ? 209 THR A CA  1 
ATOM 2925 C C   . THR C 3 209 ? 255.739 354.057 436.224 1.00 94.79  ? 209 THR A C   1 
ATOM 2926 O O   . THR C 3 209 ? 254.641 353.764 435.751 1.00 94.79  ? 209 THR A O   1 
ATOM 2927 C CB  . THR C 3 209 ? 254.864 355.925 437.575 1.00 94.79  ? 209 THR A CB  1 
ATOM 2928 O OG1 . THR C 3 209 ? 253.611 355.512 437.024 1.00 94.79  ? 209 THR A OG1 1 
ATOM 2929 C CG2 . THR C 3 209 ? 255.439 357.031 436.722 1.00 94.79  ? 209 THR A CG2 1 
ATOM 2930 N N   . LEU C 3 210 ? 256.873 353.813 435.572 1.00 94.20  ? 210 LEU A N   1 
ATOM 2931 C CA  . LEU C 3 210 ? 256.865 353.187 434.261 1.00 94.20  ? 210 LEU A CA  1 
ATOM 2932 C C   . LEU C 3 210 ? 256.750 351.669 434.329 1.00 94.20  ? 210 LEU A C   1 
ATOM 2933 O O   . LEU C 3 210 ? 256.038 351.082 433.510 1.00 94.20  ? 210 LEU A O   1 
ATOM 2934 C CB  . LEU C 3 210 ? 258.122 353.585 433.498 1.00 94.20  ? 210 LEU A CB  1 
ATOM 2935 C CG  . LEU C 3 210 ? 257.973 353.739 431.992 1.00 94.20  ? 210 LEU A CG  1 
ATOM 2936 C CD1 . LEU C 3 210 ? 256.724 354.519 431.653 1.00 94.20  ? 210 LEU A CD1 1 
ATOM 2937 C CD2 . LEU C 3 210 ? 259.190 354.443 431.447 1.00 94.20  ? 210 LEU A CD2 1 
ATOM 2938 N N   . ASN C 3 211 ? 257.426 351.005 435.267 1.00 94.87  ? 211 ASN A N   1 
ATOM 2939 C CA  . ASN C 3 211 ? 257.300 349.551 435.393 1.00 94.87  ? 211 ASN A CA  1 
ATOM 2940 C C   . ASN C 3 211 ? 256.190 349.256 436.397 1.00 94.87  ? 211 ASN A C   1 
ATOM 2941 O O   . ASN C 3 211 ? 256.414 349.123 437.598 1.00 94.87  ? 211 ASN A O   1 
ATOM 2942 C CB  . ASN C 3 211 ? 258.615 348.879 435.777 1.00 94.87  ? 211 ASN A CB  1 
ATOM 2943 C CG  . ASN C 3 211 ? 259.332 349.570 436.895 1.00 94.87  ? 211 ASN A CG  1 
ATOM 2944 O OD1 . ASN C 3 211 ? 258.912 350.617 437.347 1.00 94.87  ? 211 ASN A OD1 1 
ATOM 2945 N ND2 . ASN C 3 211 ? 260.413 348.970 437.367 1.00 94.87  ? 211 ASN A ND2 1 
ATOM 2946 N N   . ASN C 3 212 ? 254.974 349.148 435.878 1.00 99.60  ? 212 ASN A N   1 
ATOM 2947 C CA  . ASN C 3 212 ? 253.796 348.821 436.672 1.00 99.60  ? 212 ASN A CA  1 
ATOM 2948 C C   . ASN C 3 212 ? 253.059 347.719 435.928 1.00 99.60  ? 212 ASN A C   1 
ATOM 2949 O O   . ASN C 3 212 ? 252.514 347.961 434.850 1.00 99.60  ? 212 ASN A O   1 
ATOM 2950 C CB  . ASN C 3 212 ? 252.917 350.051 436.868 1.00 99.60  ? 212 ASN A CB  1 
ATOM 2951 C CG  . ASN C 3 212 ? 251.605 349.728 437.519 1.00 99.60  ? 212 ASN A CG  1 
ATOM 2952 O OD1 . ASN C 3 212 ? 250.546 349.960 436.945 1.00 99.60  ? 212 ASN A OD1 1 
ATOM 2953 N ND2 . ASN C 3 212 ? 251.662 349.181 438.724 1.00 99.60  ? 212 ASN A ND2 1 
ATOM 2954 N N   . MET C 3 213 ? 253.045 346.514 436.493 1.00 93.39  ? 213 MET A N   1 
ATOM 2955 C CA  . MET C 3 213 ? 252.635 345.338 435.740 1.00 93.39  ? 213 MET A CA  1 
ATOM 2956 C C   . MET C 3 213 ? 251.175 344.960 435.927 1.00 93.39  ? 213 MET A C   1 
ATOM 2957 O O   . MET C 3 213 ? 250.655 344.164 435.140 1.00 93.39  ? 213 MET A O   1 
ATOM 2958 C CB  . MET C 3 213 ? 253.509 344.148 436.121 1.00 93.39  ? 213 MET A CB  1 
ATOM 2959 C CG  . MET C 3 213 ? 254.928 344.529 436.445 1.00 93.39  ? 213 MET A CG  1 
ATOM 2960 S SD  . MET C 3 213 ? 255.884 343.132 437.045 1.00 93.39  ? 213 MET A SD  1 
ATOM 2961 C CE  . MET C 3 213 ? 257.248 343.982 437.823 1.00 93.39  ? 213 MET A CE  1 
ATOM 2962 N N   . GLY C 3 214 ? 250.504 345.476 436.939 1.00 86.65  ? 214 GLY A N   1 
ATOM 2963 C CA  . GLY C 3 214 ? 249.094 345.213 437.124 1.00 86.65  ? 214 GLY A CA  1 
ATOM 2964 C C   . GLY C 3 214 ? 248.834 344.469 438.412 1.00 86.65  ? 214 GLY A C   1 
ATOM 2965 O O   . GLY C 3 214 ? 249.746 344.155 439.178 1.00 86.65  ? 214 GLY A O   1 
ATOM 2966 N N   . THR C 3 215 ? 247.556 344.190 438.656 1.00 80.88  ? 215 THR A N   1 
ATOM 2967 C CA  . THR C 3 215 ? 247.117 343.547 439.885 1.00 80.88  ? 215 THR A CA  1 
ATOM 2968 C C   . THR C 3 215 ? 246.324 342.292 439.556 1.00 80.88  ? 215 THR A C   1 
ATOM 2969 O O   . THR C 3 215 ? 245.895 342.096 438.420 1.00 80.88  ? 215 THR A O   1 
ATOM 2970 C CB  . THR C 3 215 ? 246.247 344.472 440.732 1.00 80.88  ? 215 THR A CB  1 
ATOM 2971 O OG1 . THR C 3 215 ? 244.981 344.616 440.093 1.00 80.88  ? 215 THR A OG1 1 
ATOM 2972 C CG2 . THR C 3 215 ? 246.866 345.839 440.894 1.00 80.88  ? 215 THR A CG2 1 
ATOM 2973 N N   . LEU C 3 216 ? 246.132 341.444 440.562 1.00 78.82  ? 216 LEU A N   1 
ATOM 2974 C CA  . LEU C 3 216 ? 245.359 340.217 440.432 1.00 78.82  ? 216 LEU A CA  1 
ATOM 2975 C C   . LEU C 3 216 ? 244.212 340.213 441.430 1.00 78.82  ? 216 LEU A C   1 
ATOM 2976 O O   . LEU C 3 216 ? 244.309 340.825 442.494 1.00 78.82  ? 216 LEU A O   1 
ATOM 2977 C CB  . LEU C 3 216 ? 246.233 338.993 440.668 1.00 78.82  ? 216 LEU A CB  1 
ATOM 2978 C CG  . LEU C 3 216 ? 247.186 338.611 439.550 1.00 78.82  ? 216 LEU A CG  1 
ATOM 2979 C CD1 . LEU C 3 216 ? 247.931 337.377 439.939 1.00 78.82  ? 216 LEU A CD1 1 
ATOM 2980 C CD2 . LEU C 3 216 ? 246.411 338.354 438.304 1.00 78.82  ? 216 LEU A CD2 1 
ATOM 2981 N N   . TYR C 3 217 ? 243.129 339.516 441.099 1.00 84.95  ? 217 TYR A N   1 
ATOM 2982 C CA  . TYR C 3 217 ? 241.974 339.420 441.979 1.00 84.95  ? 217 TYR A CA  1 
ATOM 2983 C C   . TYR C 3 217 ? 241.352 338.041 441.896 1.00 84.95  ? 217 TYR A C   1 
ATOM 2984 O O   . TYR C 3 217 ? 241.201 337.493 440.806 1.00 84.95  ? 217 TYR A O   1 
ATOM 2985 C CB  . TYR C 3 217 ? 240.929 340.458 441.630 1.00 84.95  ? 217 TYR A CB  1 
ATOM 2986 C CG  . TYR C 3 217 ? 241.385 341.830 441.972 1.00 84.95  ? 217 TYR A CG  1 
ATOM 2987 C CD1 . TYR C 3 217 ? 241.468 342.225 443.289 1.00 84.95  ? 217 TYR A CD1 1 
ATOM 2988 C CD2 . TYR C 3 217 ? 241.764 342.716 440.994 1.00 84.95  ? 217 TYR A CD2 1 
ATOM 2989 C CE1 . TYR C 3 217 ? 241.893 343.462 443.617 1.00 84.95  ? 217 TYR A CE1 1 
ATOM 2990 C CE2 . TYR C 3 217 ? 242.192 343.966 441.318 1.00 84.95  ? 217 TYR A CE2 1 
ATOM 2991 C CZ  . TYR C 3 217 ? 242.262 344.329 442.636 1.00 84.95  ? 217 TYR A CZ  1 
ATOM 2992 O OH  . TYR C 3 217 ? 242.702 345.573 442.990 1.00 84.95  ? 217 TYR A OH  1 
ATOM 2993 N N   . MET C 3 218 ? 240.981 337.490 443.046 1.00 85.06  ? 218 MET A N   1 
ATOM 2994 C CA  . MET C 3 218 ? 240.406 336.157 443.131 1.00 85.06  ? 218 MET A CA  1 
ATOM 2995 C C   . MET C 3 218 ? 239.099 336.217 443.900 1.00 85.06  ? 218 MET A C   1 
ATOM 2996 O O   . MET C 3 218 ? 238.981 336.989 444.849 1.00 85.06  ? 218 MET A O   1 
ATOM 2997 C CB  . MET C 3 218 ? 241.360 335.195 443.825 1.00 85.06  ? 218 MET A CB  1 
ATOM 2998 C CG  . MET C 3 218 ? 242.515 334.744 442.970 1.00 85.06  ? 218 MET A CG  1 
ATOM 2999 S SD  . MET C 3 218 ? 243.879 335.918 442.922 1.00 85.06  ? 218 MET A SD  1 
ATOM 3000 C CE  . MET C 3 218 ? 244.919 335.313 444.238 1.00 85.06  ? 218 MET A CE  1 
ATOM 3001 N N   . ARG C 3 219 ? 238.129 335.393 443.501 1.00 82.31  ? 219 ARG A N   1 
ATOM 3002 C CA  . ARG C 3 219 ? 236.868 335.273 444.221 1.00 82.31  ? 219 ARG A CA  1 
ATOM 3003 C C   . ARG C 3 219 ? 236.166 333.994 443.802 1.00 82.31  ? 219 ARG A C   1 
ATOM 3004 O O   . ARG C 3 219 ? 236.481 333.404 442.769 1.00 82.31  ? 219 ARG A O   1 
ATOM 3005 C CB  . ARG C 3 219 ? 235.948 336.465 443.967 1.00 82.31  ? 219 ARG A CB  1 
ATOM 3006 C CG  . ARG C 3 219 ? 235.327 336.455 442.605 1.00 82.31  ? 219 ARG A CG  1 
ATOM 3007 C CD  . ARG C 3 219 ? 234.411 337.628 442.410 1.00 82.31  ? 219 ARG A CD  1 
ATOM 3008 N NE  . ARG C 3 219 ? 233.843 337.624 441.073 1.00 82.31  ? 219 ARG A NE  1 
ATOM 3009 C CZ  . ARG C 3 219 ? 232.570 337.377 440.816 1.00 82.31  ? 219 ARG A CZ  1 
ATOM 3010 N NH1 . ARG C 3 219 ? 231.738 337.127 441.811 1.00 82.31  ? 219 ARG A NH1 1 
ATOM 3011 N NH2 . ARG C 3 219 ? 232.132 337.387 439.570 1.00 82.31  ? 219 ARG A NH2 1 
ATOM 3012 N N   . HIS C 3 220 ? 235.209 333.573 444.623 1.00 83.63  ? 220 HIS A N   1 
ATOM 3013 C CA  . HIS C 3 220 ? 234.330 332.471 444.274 1.00 83.63  ? 220 HIS A CA  1 
ATOM 3014 C C   . HIS C 3 220 ? 233.284 332.937 443.273 1.00 83.63  ? 220 HIS A C   1 
ATOM 3015 O O   . HIS C 3 220 ? 233.056 334.132 443.100 1.00 83.63  ? 220 HIS A O   1 
ATOM 3016 C CB  . HIS C 3 220 ? 233.613 331.935 445.505 1.00 83.63  ? 220 HIS A CB  1 
ATOM 3017 C CG  . HIS C 3 220 ? 234.500 331.222 446.470 1.00 83.63  ? 220 HIS A CG  1 
ATOM 3018 N ND1 . HIS C 3 220 ? 235.205 331.878 447.453 1.00 83.63  ? 220 HIS A ND1 1 
ATOM 3019 C CD2 . HIS C 3 220 ? 234.769 329.907 446.627 1.00 83.63  ? 220 HIS A CD2 1 
ATOM 3020 C CE1 . HIS C 3 220 ? 235.883 330.998 448.163 1.00 83.63  ? 220 HIS A CE1 1 
ATOM 3021 N NE2 . HIS C 3 220 ? 235.638 329.795 447.681 1.00 83.63  ? 220 HIS A NE2 1 
ATOM 3022 N N   . VAL C 3 221 ? 232.626 331.985 442.616 1.00 84.82  ? 221 VAL A N   1 
ATOM 3023 C CA  . VAL C 3 221 ? 231.472 332.357 441.806 1.00 84.82  ? 221 VAL A CA  1 
ATOM 3024 C C   . VAL C 3 221 ? 230.268 331.512 442.189 1.00 84.82  ? 221 VAL A C   1 
ATOM 3025 O O   . VAL C 3 221 ? 229.218 331.589 441.546 1.00 84.82  ? 221 VAL A O   1 
ATOM 3026 C CB  . VAL C 3 221 ? 231.745 332.232 440.299 1.00 84.82  ? 221 VAL A CB  1 
ATOM 3027 C CG1 . VAL C 3 221 ? 232.703 333.287 439.834 1.00 84.82  ? 221 VAL A CG1 1 
ATOM 3028 C CG2 . VAL C 3 221 ? 232.269 330.896 439.984 1.00 84.82  ? 221 VAL A CG2 1 
ATOM 3029 N N   . ASN C 3 222 ? 230.395 330.709 443.236 1.00 95.72  ? 222 ASN A N   1 
ATOM 3030 C CA  . ASN C 3 222 ? 229.272 329.951 443.762 1.00 95.72  ? 222 ASN A CA  1 
ATOM 3031 C C   . ASN C 3 222 ? 228.751 330.645 445.007 1.00 95.72  ? 222 ASN A C   1 
ATOM 3032 O O   . ASN C 3 222 ? 229.525 330.998 445.898 1.00 95.72  ? 222 ASN A O   1 
ATOM 3033 C CB  . ASN C 3 222 ? 229.661 328.519 444.112 1.00 95.72  ? 222 ASN A CB  1 
ATOM 3034 C CG  . ASN C 3 222 ? 229.844 327.654 442.899 1.00 95.72  ? 222 ASN A CG  1 
ATOM 3035 O OD1 . ASN C 3 222 ? 230.904 327.071 442.694 1.00 95.72  ? 222 ASN A OD1 1 
ATOM 3036 N ND2 . ASN C 3 222 ? 228.812 327.565 442.079 1.00 95.72  ? 222 ASN A ND2 1 
ATOM 3037 N N   . GLU C 3 223 ? 227.445 330.836 445.073 1.00 110.16 ? 223 GLU A N   1 
ATOM 3038 C CA  . GLU C 3 223 ? 226.811 331.406 446.251 1.00 110.16 ? 223 GLU A CA  1 
ATOM 3039 C C   . GLU C 3 223 ? 226.542 330.282 447.241 1.00 110.16 ? 223 GLU A C   1 
ATOM 3040 O O   . GLU C 3 223 ? 226.122 329.191 446.849 1.00 110.16 ? 223 GLU A O   1 
ATOM 3041 C CB  . GLU C 3 223 ? 225.515 332.145 445.899 1.00 110.16 ? 223 GLU A CB  1 
ATOM 3042 C CG  . GLU C 3 223 ? 224.486 331.378 445.065 1.00 110.16 ? 223 GLU A CG  1 
ATOM 3043 C CD  . GLU C 3 223 ? 224.778 331.378 443.573 1.00 110.16 ? 223 GLU A CD  1 
ATOM 3044 O OE1 . GLU C 3 223 ? 225.791 331.980 443.162 1.00 110.16 ? 223 GLU A OE1 1 
ATOM 3045 O OE2 . GLU C 3 223 ? 223.996 330.770 442.813 1.00 110.16 ? 223 GLU A OE2 1 
ATOM 3046 N N   . ALA C 3 224 ? 226.807 330.541 448.514 1.00 119.40 ? 224 ALA A N   1 
ATOM 3047 C CA  . ALA C 3 224 ? 226.745 329.513 449.540 1.00 119.40 ? 224 ALA A CA  1 
ATOM 3048 C C   . ALA C 3 224 ? 225.306 329.326 449.988 1.00 119.40 ? 224 ALA A C   1 
ATOM 3049 O O   . ALA C 3 224 ? 224.554 330.296 450.106 1.00 119.40 ? 224 ALA A O   1 
ATOM 3050 C CB  . ALA C 3 224 ? 227.617 329.874 450.739 1.00 119.40 ? 224 ALA A CB  1 
ATOM 3051 N N   . GLY C 3 225 ? 224.929 328.077 450.232 1.00 125.40 ? 225 GLY A N   1 
ATOM 3052 C CA  . GLY C 3 225 ? 223.563 327.800 450.616 1.00 125.40 ? 225 GLY A CA  1 
ATOM 3053 C C   . GLY C 3 225 ? 223.417 327.245 452.013 1.00 125.40 ? 225 GLY A C   1 
ATOM 3054 O O   . GLY C 3 225 ? 222.461 327.585 452.717 1.00 125.40 ? 225 GLY A O   1 
ATOM 3055 N N   . GLN C 3 226 ? 224.335 326.377 452.433 1.00 128.79 ? 226 GLN A N   1 
ATOM 3056 C CA  . GLN C 3 226 ? 224.257 325.765 453.746 1.00 128.79 ? 226 GLN A CA  1 
ATOM 3057 C C   . GLN C 3 226 ? 225.529 325.831 454.583 1.00 128.79 ? 226 GLN A C   1 
ATOM 3058 O O   . GLN C 3 226 ? 225.450 325.686 455.808 1.00 128.79 ? 226 GLN A O   1 
ATOM 3059 C CB  . GLN C 3 226 ? 223.800 324.303 453.606 1.00 128.79 ? 226 GLN A CB  1 
ATOM 3060 C CG  . GLN C 3 226 ? 222.393 324.123 453.055 1.00 128.79 ? 226 GLN A CG  1 
ATOM 3061 C CD  . GLN C 3 226 ? 221.329 324.673 453.978 1.00 128.79 ? 226 GLN A CD  1 
ATOM 3062 O OE1 . GLN C 3 226 ? 220.824 325.776 453.771 1.00 128.79 ? 226 GLN A OE1 1 
ATOM 3063 N NE2 . GLN C 3 226 ? 220.999 323.915 455.022 1.00 128.79 ? 226 GLN A NE2 1 
ATOM 3064 N N   . GLY C 3 227 ? 226.687 326.046 453.972 1.00 119.07 ? 227 GLY A N   1 
ATOM 3065 C CA  . GLY C 3 227 ? 227.921 326.063 454.719 1.00 119.07 ? 227 GLY A CA  1 
ATOM 3066 C C   . GLY C 3 227 ? 228.972 327.000 454.167 1.00 119.07 ? 227 GLY A C   1 
ATOM 3067 O O   . GLY C 3 227 ? 229.195 327.073 452.956 1.00 119.07 ? 227 GLY A O   1 
ATOM 3068 N N   . PRO C 3 228 ? 229.638 327.738 455.045 1.00 108.81 ? 228 PRO A N   1 
ATOM 3069 C CA  . PRO C 3 228 ? 230.734 328.598 454.603 1.00 108.81 ? 228 PRO A CA  1 
ATOM 3070 C C   . PRO C 3 228 ? 231.953 327.782 454.222 1.00 108.81 ? 228 PRO A C   1 
ATOM 3071 O O   . PRO C 3 228 ? 232.225 326.722 454.786 1.00 108.81 ? 228 PRO A O   1 
ATOM 3072 C CB  . PRO C 3 228 ? 231.022 329.469 455.832 1.00 108.81 ? 228 PRO A CB  1 
ATOM 3073 C CG  . PRO C 3 228 ? 229.867 329.267 456.745 1.00 108.81 ? 228 PRO A CG  1 
ATOM 3074 C CD  . PRO C 3 228 ? 229.373 327.894 456.479 1.00 108.81 ? 228 PRO A CD  1 
ATOM 3075 N N   . ILE C 3 229 ? 232.678 328.282 453.225 1.00 98.06  ? 229 ILE A N   1 
ATOM 3076 C CA  . ILE C 3 229 ? 233.896 327.653 452.732 1.00 98.06  ? 229 ILE A CA  1 
ATOM 3077 C C   . ILE C 3 229 ? 234.925 328.752 452.545 1.00 98.06  ? 229 ILE A C   1 
ATOM 3078 O O   . ILE C 3 229 ? 234.665 329.722 451.829 1.00 98.06  ? 229 ILE A O   1 
ATOM 3079 C CB  . ILE C 3 229 ? 233.672 326.912 451.403 1.00 98.06  ? 229 ILE A CB  1 
ATOM 3080 C CG1 . ILE C 3 229 ? 232.838 325.651 451.619 1.00 98.06  ? 229 ILE A CG1 1 
ATOM 3081 C CG2 . ILE C 3 229 ? 234.991 326.565 450.754 1.00 98.06  ? 229 ILE A CG2 1 
ATOM 3082 C CD1 . ILE C 3 229 ? 232.704 324.779 450.392 1.00 98.06  ? 229 ILE A CD1 1 
ATOM 3083 N N   . LYS C 3 230 ? 236.078 328.623 453.189 1.00 93.06  ? 230 LYS A N   1 
ATOM 3084 C CA  . LYS C 3 230 ? 237.182 329.536 452.940 1.00 93.06  ? 230 LYS A CA  1 
ATOM 3085 C C   . LYS C 3 230 ? 238.282 328.816 452.176 1.00 93.06  ? 230 LYS A C   1 
ATOM 3086 O O   . LYS C 3 230 ? 238.434 327.597 452.262 1.00 93.06  ? 230 LYS A O   1 
ATOM 3087 C CB  . LYS C 3 230 ? 237.720 330.127 454.241 1.00 93.06  ? 230 LYS A CB  1 
ATOM 3088 C CG  . LYS C 3 230 ? 238.526 329.181 455.082 1.00 93.06  ? 230 LYS A CG  1 
ATOM 3089 C CD  . LYS C 3 230 ? 239.168 329.912 456.235 1.00 93.06  ? 230 LYS A CD  1 
ATOM 3090 C CE  . LYS C 3 230 ? 240.138 330.956 455.739 1.00 93.06  ? 230 LYS A CE  1 
ATOM 3091 N NZ  . LYS C 3 230 ? 240.734 331.707 456.869 1.00 93.06  ? 230 LYS A NZ  1 
ATOM 3092 N N   . SER C 3 231 ? 239.042 329.582 451.405 1.00 86.35  ? 231 SER A N   1 
ATOM 3093 C CA  . SER C 3 231 ? 240.002 328.992 450.488 1.00 86.35  ? 231 SER A CA  1 
ATOM 3094 C C   . SER C 3 231 ? 241.288 329.790 450.511 1.00 86.35  ? 231 SER A C   1 
ATOM 3095 O O   . SER C 3 231 ? 241.266 331.003 450.717 1.00 86.35  ? 231 SER A O   1 
ATOM 3096 C CB  . SER C 3 231 ? 239.450 328.955 449.069 1.00 86.35  ? 231 SER A CB  1 
ATOM 3097 O OG  . SER C 3 231 ? 238.215 328.275 449.040 1.00 86.35  ? 231 SER A OG  1 
ATOM 3098 N N   . THR C 3 232 ? 242.402 329.108 450.297 1.00 86.78  ? 232 THR A N   1 
ATOM 3099 C CA  . THR C 3 232 ? 243.708 329.739 450.219 1.00 86.78  ? 232 THR A CA  1 
ATOM 3100 C C   . THR C 3 232 ? 244.212 329.672 448.788 1.00 86.78  ? 232 THR A C   1 
ATOM 3101 O O   . THR C 3 232 ? 243.669 328.952 447.950 1.00 86.78  ? 232 THR A O   1 
ATOM 3102 C CB  . THR C 3 232 ? 244.703 329.059 451.156 1.00 86.78  ? 232 THR A CB  1 
ATOM 3103 O OG1 . THR C 3 232 ? 244.972 327.741 450.676 1.00 86.78  ? 232 THR A OG1 1 
ATOM 3104 C CG2 . THR C 3 232 ? 244.127 328.947 452.542 1.00 86.78  ? 232 THR A CG2 1 
ATOM 3105 N N   . VAL C 3 233 ? 245.272 330.420 448.515 1.00 80.74  ? 233 VAL A N   1 
ATOM 3106 C CA  . VAL C 3 233 ? 245.845 330.477 447.177 1.00 80.74  ? 233 VAL A CA  1 
ATOM 3107 C C   . VAL C 3 233 ? 247.315 330.848 447.303 1.00 80.74  ? 233 VAL A C   1 
ATOM 3108 O O   . VAL C 3 233 ? 247.673 331.736 448.078 1.00 80.74  ? 233 VAL A O   1 
ATOM 3109 C CB  . VAL C 3 233 ? 245.053 331.458 446.287 1.00 80.74  ? 233 VAL A CB  1 
ATOM 3110 C CG1 . VAL C 3 233 ? 244.817 332.763 446.999 1.00 80.74  ? 233 VAL A CG1 1 
ATOM 3111 C CG2 . VAL C 3 233 ? 245.744 331.696 444.972 1.00 80.74  ? 233 VAL A CG2 1 
ATOM 3112 N N   . ARG C 3 234 ? 248.177 330.129 446.591 1.00 81.81  ? 234 ARG A N   1 
ATOM 3113 C CA  . ARG C 3 234 ? 249.611 330.384 446.603 1.00 81.81  ? 234 ARG A CA  1 
ATOM 3114 C C   . ARG C 3 234 ? 250.042 330.728 445.191 1.00 81.81  ? 234 ARG A C   1 
ATOM 3115 O O   . ARG C 3 234 ? 250.166 329.840 444.346 1.00 81.81  ? 234 ARG A O   1 
ATOM 3116 C CB  . ARG C 3 234 ? 250.382 329.176 447.117 1.00 81.81  ? 234 ARG A CB  1 
ATOM 3117 C CG  . ARG C 3 234 ? 249.775 328.557 448.332 1.00 81.81  ? 234 ARG A CG  1 
ATOM 3118 C CD  . ARG C 3 234 ? 250.389 327.223 448.642 1.00 81.81  ? 234 ARG A CD  1 
ATOM 3119 N NE  . ARG C 3 234 ? 249.592 326.527 449.637 1.00 81.81  ? 234 ARG A NE  1 
ATOM 3120 C CZ  . ARG C 3 234 ? 249.775 326.649 450.942 1.00 81.81  ? 234 ARG A CZ  1 
ATOM 3121 N NH1 . ARG C 3 234 ? 250.738 327.431 451.402 1.00 81.81  ? 234 ARG A NH1 1 
ATOM 3122 N NH2 . ARG C 3 234 ? 249.003 325.987 451.787 1.00 81.81  ? 234 ARG A NH2 1 
ATOM 3123 N N   . ILE C 3 235 ? 250.275 332.001 444.935 1.00 77.87  ? 235 ILE A N   1 
ATOM 3124 C CA  . ILE C 3 235 ? 250.680 332.441 443.609 1.00 77.87  ? 235 ILE A CA  1 
ATOM 3125 C C   . ILE C 3 235 ? 252.144 332.103 443.399 1.00 77.87  ? 235 ILE A C   1 
ATOM 3126 O O   . ILE C 3 235 ? 252.999 332.484 444.202 1.00 77.87  ? 235 ILE A O   1 
ATOM 3127 C CB  . ILE C 3 235 ? 250.433 333.942 443.448 1.00 77.87  ? 235 ILE A CB  1 
ATOM 3128 C CG1 . ILE C 3 235 ? 248.973 334.252 443.727 1.00 77.87  ? 235 ILE A CG1 1 
ATOM 3129 C CG2 . ILE C 3 235 ? 250.806 334.383 442.073 1.00 77.87  ? 235 ILE A CG2 1 
ATOM 3130 C CD1 . ILE C 3 235 ? 248.637 335.698 443.609 1.00 77.87  ? 235 ILE A CD1 1 
ATOM 3131 N N   . TYR C 3 236 ? 252.443 331.390 442.324 1.00 77.34  ? 236 TYR A N   1 
ATOM 3132 C CA  . TYR C 3 236 ? 253.817 331.081 441.969 1.00 77.34  ? 236 TYR A CA  1 
ATOM 3133 C C   . TYR C 3 236 ? 254.257 331.963 440.812 1.00 77.34  ? 236 TYR A C   1 
ATOM 3134 O O   . TYR C 3 236 ? 253.432 332.527 440.094 1.00 77.34  ? 236 TYR A O   1 
ATOM 3135 C CB  . TYR C 3 236 ? 253.976 329.609 441.619 1.00 77.34  ? 236 TYR A CB  1 
ATOM 3136 C CG  . TYR C 3 236 ? 254.140 328.753 442.841 1.00 77.34  ? 236 TYR A CG  1 
ATOM 3137 C CD1 . TYR C 3 236 ? 253.043 328.224 443.485 1.00 77.34  ? 236 TYR A CD1 1 
ATOM 3138 C CD2 . TYR C 3 236 ? 255.391 328.500 443.365 1.00 77.34  ? 236 TYR A CD2 1 
ATOM 3139 C CE1 . TYR C 3 236 ? 253.187 327.455 444.607 1.00 77.34  ? 236 TYR A CE1 1 
ATOM 3140 C CE2 . TYR C 3 236 ? 255.544 327.731 444.488 1.00 77.34  ? 236 TYR A CE2 1 
ATOM 3141 C CZ  . TYR C 3 236 ? 254.440 327.212 445.104 1.00 77.34  ? 236 TYR A CZ  1 
ATOM 3142 O OH  . TYR C 3 236 ? 254.594 326.444 446.227 1.00 77.34  ? 236 TYR A OH  1 
ATOM 3143 N N   . PHE C 3 237 ? 255.565 332.073 440.634 1.00 80.63  ? 237 PHE A N   1 
ATOM 3144 C CA  . PHE C 3 237 ? 256.170 333.149 439.865 1.00 80.63  ? 237 PHE A CA  1 
ATOM 3145 C C   . PHE C 3 237 ? 257.360 332.608 439.101 1.00 80.63  ? 237 PHE A C   1 
ATOM 3146 O O   . PHE C 3 237 ? 258.246 331.995 439.696 1.00 80.63  ? 237 PHE A O   1 
ATOM 3147 C CB  . PHE C 3 237 ? 256.601 334.259 440.817 1.00 80.63  ? 237 PHE A CB  1 
ATOM 3148 C CG  . PHE C 3 237 ? 257.086 335.498 440.150 1.00 80.63  ? 237 PHE A CG  1 
ATOM 3149 C CD1 . PHE C 3 237 ? 256.198 336.474 439.755 1.00 80.63  ? 237 PHE A CD1 1 
ATOM 3150 C CD2 . PHE C 3 237 ? 258.437 335.717 439.976 1.00 80.63  ? 237 PHE A CD2 1 
ATOM 3151 C CE1 . PHE C 3 237 ? 256.647 337.630 439.168 1.00 80.63  ? 237 PHE A CE1 1 
ATOM 3152 C CE2 . PHE C 3 237 ? 258.892 336.867 439.387 1.00 80.63  ? 237 PHE A CE2 1 
ATOM 3153 C CZ  . PHE C 3 237 ? 257.996 337.826 438.986 1.00 80.63  ? 237 PHE A CZ  1 
ATOM 3154 N N   . LYS C 3 238 ? 257.399 332.845 437.802 1.00 84.50  ? 238 LYS A N   1 
ATOM 3155 C CA  . LYS C 3 238 ? 258.474 332.270 437.010 1.00 84.50  ? 238 LYS A CA  1 
ATOM 3156 C C   . LYS C 3 238 ? 258.780 333.124 435.790 1.00 84.50  ? 238 LYS A C   1 
ATOM 3157 O O   . LYS C 3 238 ? 257.976 333.166 434.856 1.00 84.50  ? 238 LYS A O   1 
ATOM 3158 C CB  . LYS C 3 238 ? 258.102 330.859 436.573 1.00 84.50  ? 238 LYS A CB  1 
ATOM 3159 C CG  . LYS C 3 238 ? 259.143 330.167 435.727 1.00 84.50  ? 238 LYS A CG  1 
ATOM 3160 C CD  . LYS C 3 238 ? 258.698 328.758 435.398 1.00 84.50  ? 238 LYS A CD  1 
ATOM 3161 C CE  . LYS C 3 238 ? 259.773 327.995 434.672 1.00 84.50  ? 238 LYS A CE  1 
ATOM 3162 N NZ  . LYS C 3 238 ? 260.211 328.726 433.463 1.00 84.50  ? 238 LYS A NZ  1 
ATOM 3163 N N   . PRO C 3 239 ? 259.915 333.812 435.759 1.00 82.62  ? 239 PRO A N   1 
ATOM 3164 C CA  . PRO C 3 239 ? 260.277 334.586 434.570 1.00 82.62  ? 239 PRO A CA  1 
ATOM 3165 C C   . PRO C 3 239 ? 260.641 333.683 433.405 1.00 82.62  ? 239 PRO A C   1 
ATOM 3166 O O   . PRO C 3 239 ? 260.905 332.493 433.562 1.00 82.62  ? 239 PRO A O   1 
ATOM 3167 C CB  . PRO C 3 239 ? 261.486 335.398 435.034 1.00 82.62  ? 239 PRO A CB  1 
ATOM 3168 C CG  . PRO C 3 239 ? 261.431 335.362 436.506 1.00 82.62  ? 239 PRO A CG  1 
ATOM 3169 C CD  . PRO C 3 239 ? 260.847 334.055 436.863 1.00 82.62  ? 239 PRO A CD  1 
ATOM 3170 N N   . LYS C 3 240 ? 260.642 334.271 432.215 1.00 89.86  ? 240 LYS A N   1 
ATOM 3171 C CA  . LYS C 3 240 ? 261.023 333.551 431.011 1.00 89.86  ? 240 LYS A CA  1 
ATOM 3172 C C   . LYS C 3 240 ? 261.703 334.506 430.048 1.00 89.86  ? 240 LYS A C   1 
ATOM 3173 O O   . LYS C 3 240 ? 261.306 335.669 429.951 1.00 89.86  ? 240 LYS A O   1 
ATOM 3174 C CB  . LYS C 3 240 ? 259.820 332.930 430.315 1.00 89.86  ? 240 LYS A CB  1 
ATOM 3175 C CG  . LYS C 3 240 ? 259.455 331.541 430.765 1.00 89.86  ? 240 LYS A CG  1 
ATOM 3176 C CD  . LYS C 3 240 ? 258.623 330.837 429.703 1.00 89.86  ? 240 LYS A CD  1 
ATOM 3177 C CE  . LYS C 3 240 ? 257.497 331.723 429.193 1.00 89.86  ? 240 LYS A CE  1 
ATOM 3178 N NZ  . LYS C 3 240 ? 256.690 331.034 428.161 1.00 89.86  ? 240 LYS A NZ  1 
ATOM 3179 N N   . HIS C 3 241 ? 262.699 333.985 429.323 1.00 91.15  ? 241 HIS A N   1 
ATOM 3180 C CA  . HIS C 3 241 ? 263.501 334.723 428.343 1.00 91.15  ? 241 HIS A CA  1 
ATOM 3181 C C   . HIS C 3 241 ? 264.134 335.964 428.968 1.00 91.15  ? 241 HIS A C   1 
ATOM 3182 O O   . HIS C 3 241 ? 263.950 337.091 428.511 1.00 91.15  ? 241 HIS A O   1 
ATOM 3183 C CB  . HIS C 3 241 ? 262.677 335.090 427.107 1.00 91.15  ? 241 HIS A CB  1 
ATOM 3184 C CG  . HIS C 3 241 ? 261.899 333.948 426.543 1.00 91.15  ? 241 HIS A CG  1 
ATOM 3185 N ND1 . HIS C 3 241 ? 260.585 334.067 426.149 1.00 91.15  ? 241 HIS A ND1 1 
ATOM 3186 C CD2 . HIS C 3 241 ? 262.249 332.664 426.305 1.00 91.15  ? 241 HIS A CD2 1 
ATOM 3187 C CE1 . HIS C 3 241 ? 260.158 332.902 425.695 1.00 91.15  ? 241 HIS A CE1 1 
ATOM 3188 N NE2 . HIS C 3 241 ? 261.149 332.035 425.778 1.00 91.15  ? 241 HIS A NE2 1 
ATOM 3189 N N   . VAL C 3 242 ? 264.879 335.733 430.028 1.00 85.43  ? 242 VAL A N   1 
ATOM 3190 C CA  . VAL C 3 242 ? 265.421 336.820 430.827 1.00 85.43  ? 242 VAL A CA  1 
ATOM 3191 C C   . VAL C 3 242 ? 266.630 337.412 430.123 1.00 85.43  ? 242 VAL A C   1 
ATOM 3192 O O   . VAL C 3 242 ? 267.468 336.688 429.581 1.00 85.43  ? 242 VAL A O   1 
ATOM 3193 C CB  . VAL C 3 242 ? 265.781 336.311 432.229 1.00 85.43  ? 242 VAL A CB  1 
ATOM 3194 C CG1 . VAL C 3 242 ? 265.996 337.460 433.164 1.00 85.43  ? 242 VAL A CG1 1 
ATOM 3195 C CG2 . VAL C 3 242 ? 264.688 335.427 432.742 1.00 85.43  ? 242 VAL A CG2 1 
ATOM 3196 N N   . LYS C 3 243 ? 266.701 338.738 430.097 1.00 83.78  ? 243 LYS A N   1 
ATOM 3197 C CA  . LYS C 3 243 ? 267.890 339.462 429.680 1.00 83.78  ? 243 LYS A CA  1 
ATOM 3198 C C   . LYS C 3 243 ? 268.247 340.436 430.786 1.00 83.78  ? 243 LYS A C   1 
ATOM 3199 O O   . LYS C 3 243 ? 267.362 341.092 431.339 1.00 83.78  ? 243 LYS A O   1 
ATOM 3200 C CB  . LYS C 3 243 ? 267.664 340.214 428.376 1.00 83.78  ? 243 LYS A CB  1 
ATOM 3201 C CG  . LYS C 3 243 ? 267.242 339.338 427.229 1.00 83.78  ? 243 LYS A CG  1 
ATOM 3202 C CD  . LYS C 3 243 ? 267.031 340.150 425.974 1.00 83.78  ? 243 LYS A CD  1 
ATOM 3203 C CE  . LYS C 3 243 ? 266.343 339.322 424.915 1.00 83.78  ? 243 LYS A CE  1 
ATOM 3204 N NZ  . LYS C 3 243 ? 267.171 338.162 424.504 1.00 83.78  ? 243 LYS A NZ  1 
ATOM 3205 N N   . ALA C 3 244 ? 269.525 340.529 431.115 1.00 82.49  ? 244 ALA A N   1 
ATOM 3206 C CA  . ALA C 3 244 ? 269.977 341.406 432.180 1.00 82.49  ? 244 ALA A CA  1 
ATOM 3207 C C   . ALA C 3 244 ? 270.931 342.440 431.615 1.00 82.49  ? 244 ALA A C   1 
ATOM 3208 O O   . ALA C 3 244 ? 271.445 342.281 430.509 1.00 82.49  ? 244 ALA A O   1 
ATOM 3209 C CB  . ALA C 3 244 ? 270.661 340.625 433.287 1.00 82.49  ? 244 ALA A CB  1 
ATOM 3210 N N   . TRP C 3 245 ? 271.178 343.498 432.343 1.00 80.89  ? 245 TRP A N   1 
ATOM 3211 C CA  . TRP C 3 245 ? 272.033 344.517 431.849 1.00 80.89  ? 245 TRP A CA  1 
ATOM 3212 C C   . TRP C 3 245 ? 272.767 345.200 432.973 1.00 80.89  ? 245 TRP A C   1 
ATOM 3213 O O   . TRP C 3 245 ? 272.226 345.330 433.981 1.00 80.89  ? 245 TRP A O   1 
ATOM 3214 C CB  . TRP C 3 245 ? 271.113 345.443 431.164 1.00 80.89  ? 245 TRP A CB  1 
ATOM 3215 C CG  . TRP C 3 245 ? 270.945 345.143 429.825 1.00 80.89  ? 245 TRP A CG  1 
ATOM 3216 C CD1 . TRP C 3 245 ? 271.879 345.068 428.963 1.00 80.89  ? 245 TRP A CD1 1 
ATOM 3217 C CD2 . TRP C 3 245 ? 269.758 344.906 429.147 1.00 80.89  ? 245 TRP A CD2 1 
ATOM 3218 N NE1 . TRP C 3 245 ? 271.401 344.792 427.756 1.00 80.89  ? 245 TRP A NE1 1 
ATOM 3219 C CE2 . TRP C 3 245 ? 270.067 344.687 427.862 1.00 80.89  ? 245 TRP A CE2 1 
ATOM 3220 C CE3 . TRP C 3 245 ? 268.462 344.843 429.513 1.00 80.89  ? 245 TRP A CE3 1 
ATOM 3221 C CZ2 . TRP C 3 245 ? 269.154 344.418 426.949 1.00 80.89  ? 245 TRP A CZ2 1 
ATOM 3222 C CZ3 . TRP C 3 245 ? 267.564 344.588 428.611 1.00 80.89  ? 245 TRP A CZ3 1 
ATOM 3223 C CH2 . TRP C 3 245 ? 267.897 344.368 427.351 1.00 80.89  ? 245 TRP A CH2 1 
ATOM 3224 N N   . VAL C 3 246 ? 273.989 345.654 432.836 1.00 79.00  ? 246 VAL A N   1 
ATOM 3225 C CA  . VAL C 3 246 ? 274.665 346.303 433.964 1.00 79.00  ? 246 VAL A CA  1 
ATOM 3226 C C   . VAL C 3 246 ? 274.687 345.713 435.358 1.00 79.00  ? 246 VAL A C   1 
ATOM 3227 O O   . VAL C 3 246 ? 274.017 346.142 436.177 1.00 79.00  ? 246 VAL A O   1 
ATOM 3228 C CB  . VAL C 3 246 ? 274.510 347.812 433.981 1.00 79.00  ? 246 VAL A CB  1 
ATOM 3229 C CG1 . VAL C 3 246 ? 273.095 348.131 434.074 1.00 79.00  ? 246 VAL A CG1 1 
ATOM 3230 C CG2 . VAL C 3 246 ? 275.080 348.474 435.161 1.00 79.00  ? 246 VAL A CG2 1 
ATOM 3231 N N   . PRO C 3 247 ? 275.519 344.753 435.690 1.00 77.34  ? 247 PRO A N   1 
ATOM 3232 C CA  . PRO C 3 247 ? 275.488 344.134 437.004 1.00 77.34  ? 247 PRO A CA  1 
ATOM 3233 C C   . PRO C 3 247 ? 275.785 344.974 438.177 1.00 77.34  ? 247 PRO A C   1 
ATOM 3234 O O   . PRO C 3 247 ? 276.582 345.789 438.015 1.00 77.34  ? 247 PRO A O   1 
ATOM 3235 C CB  . PRO C 3 247 ? 276.603 343.202 436.838 1.00 77.34  ? 247 PRO A CB  1 
ATOM 3236 C CG  . PRO C 3 247 ? 277.546 343.997 436.108 1.00 77.34  ? 247 PRO A CG  1 
ATOM 3237 C CD  . PRO C 3 247 ? 276.753 344.626 435.062 1.00 77.34  ? 247 PRO A CD  1 
ATOM 3238 N N   . ARG C 3 248 ? 275.211 344.762 439.352 1.00 81.22  ? 248 ARG A N   1 
ATOM 3239 C CA  . ARG C 3 248 ? 275.554 345.483 440.566 1.00 81.22  ? 248 ARG A CA  1 
ATOM 3240 C C   . ARG C 3 248 ? 275.958 344.787 441.842 1.00 81.22  ? 248 ARG A C   1 
ATOM 3241 O O   . ARG C 3 248 ? 275.473 343.775 442.033 1.00 81.22  ? 248 ARG A O   1 
ATOM 3242 C CB  . ARG C 3 248 ? 274.269 346.116 440.872 1.00 81.22  ? 248 ARG A CB  1 
ATOM 3243 C CG  . ARG C 3 248 ? 274.359 347.102 441.969 1.00 81.22  ? 248 ARG A CG  1 
ATOM 3244 C CD  . ARG C 3 248 ? 272.987 347.659 442.241 1.00 81.22  ? 248 ARG A CD  1 
ATOM 3245 N NE  . ARG C 3 248 ? 272.527 348.394 441.106 1.00 81.22  ? 248 ARG A NE  1 
ATOM 3246 C CZ  . ARG C 3 248 ? 272.832 349.634 440.880 1.00 81.22  ? 248 ARG A CZ  1 
ATOM 3247 N NH1 . ARG C 3 248 ? 273.561 350.292 441.719 1.00 81.22  ? 248 ARG A NH1 1 
ATOM 3248 N NH2 . ARG C 3 248 ? 272.392 350.204 439.811 1.00 81.22  ? 248 ARG A NH2 1 
ATOM 3249 N N   . PRO C 3 249 ? 276.767 345.314 442.751 1.00 78.63  ? 249 PRO A N   1 
ATOM 3250 C CA  . PRO C 3 249 ? 277.210 344.510 443.879 1.00 78.63  ? 249 PRO A CA  1 
ATOM 3251 C C   . PRO C 3 249 ? 276.038 344.243 444.699 1.00 78.63  ? 249 PRO A C   1 
ATOM 3252 O O   . PRO C 3 249 ? 275.332 345.130 444.867 1.00 78.63  ? 249 PRO A O   1 
ATOM 3253 C CB  . PRO C 3 249 ? 278.024 345.424 444.708 1.00 78.63  ? 249 PRO A CB  1 
ATOM 3254 C CG  . PRO C 3 249 ? 277.460 346.715 444.452 1.00 78.63  ? 249 PRO A CG  1 
ATOM 3255 C CD  . PRO C 3 249 ? 277.283 346.712 442.991 1.00 78.63  ? 249 PRO A CD  1 
ATOM 3256 N N   . PRO C 3 250 ? 275.906 343.089 445.305 1.00 84.09  ? 250 PRO A N   1 
ATOM 3257 C CA  . PRO C 3 250 ? 274.898 342.436 446.128 1.00 84.09  ? 250 PRO A CA  1 
ATOM 3258 C C   . PRO C 3 250 ? 274.691 343.140 447.400 1.00 84.09  ? 250 PRO A C   1 
ATOM 3259 O O   . PRO C 3 250 ? 275.669 343.459 447.931 1.00 84.09  ? 250 PRO A O   1 
ATOM 3260 C CB  . PRO C 3 250 ? 275.559 341.145 446.463 1.00 84.09  ? 250 PRO A CB  1 
ATOM 3261 C CG  . PRO C 3 250 ? 276.614 340.993 445.475 1.00 84.09  ? 250 PRO A CG  1 
ATOM 3262 C CD  . PRO C 3 250 ? 277.133 342.349 445.345 1.00 84.09  ? 250 PRO A CD  1 
ATOM 3263 N N   . ARG C 3 251 ? 273.506 343.170 447.967 1.00 87.10  ? 251 ARG A N   1 
ATOM 3264 C CA  . ARG C 3 251 ? 273.144 343.988 449.116 1.00 87.10  ? 251 ARG A CA  1 
ATOM 3265 C C   . ARG C 3 251 ? 273.625 343.363 450.414 1.00 87.10  ? 251 ARG A C   1 
ATOM 3266 O O   . ARG C 3 251 ? 273.369 342.189 450.683 1.00 87.10  ? 251 ARG A O   1 
ATOM 3267 C CB  . ARG C 3 251 ? 271.638 344.181 449.161 1.00 87.10  ? 251 ARG A CB  1 
ATOM 3268 C CG  . ARG C 3 251 ? 271.166 345.005 450.324 1.00 87.10  ? 251 ARG A CG  1 
ATOM 3269 C CD  . ARG C 3 251 ? 269.876 345.692 449.977 1.00 87.10  ? 251 ARG A CD  1 
ATOM 3270 N NE  . ARG C 3 251 ? 269.129 346.067 451.166 1.00 87.10  ? 251 ARG A NE  1 
ATOM 3271 C CZ  . ARG C 3 251 ? 269.072 347.302 451.635 1.00 87.10  ? 251 ARG A CZ  1 
ATOM 3272 N NH1 . ARG C 3 251 ? 269.712 348.267 451.005 1.00 87.10  ? 251 ARG A NH1 1 
ATOM 3273 N NH2 . ARG C 3 251 ? 268.373 347.569 452.725 1.00 87.10  ? 251 ARG A NH2 1 
ATOM 3274 N N   . LEU C 3 252 ? 274.307 344.162 451.228 1.00 87.08  ? 252 LEU A N   1 
ATOM 3275 C CA  . LEU C 3 252 ? 274.897 343.718 452.483 1.00 87.08  ? 252 LEU A CA  1 
ATOM 3276 C C   . LEU C 3 252 ? 273.927 343.821 453.651 1.00 87.08  ? 252 LEU A C   1 
ATOM 3277 O O   . LEU C 3 252 ? 273.773 342.869 454.417 1.00 87.08  ? 252 LEU A O   1 
ATOM 3278 C CB  . LEU C 3 252 ? 276.141 344.550 452.782 1.00 87.08  ? 252 LEU A CB  1 
ATOM 3279 C CG  . LEU C 3 252 ? 276.870 344.268 454.085 1.00 87.08  ? 252 LEU A CG  1 
ATOM 3280 C CD1 . LEU C 3 252 ? 277.450 342.888 454.064 1.00 87.08  ? 252 LEU A CD1 1 
ATOM 3281 C CD2 . LEU C 3 252 ? 277.952 345.292 454.286 1.00 87.08  ? 252 LEU A CD2 1 
ATOM 3282 N N   . CYS C 3 253 ? 273.277 344.969 453.802 1.00 94.02  ? 253 CYS A N   1 
ATOM 3283 C CA  . CYS C 3 253 ? 272.378 345.212 454.916 1.00 94.02  ? 253 CYS A CA  1 
ATOM 3284 C C   . CYS C 3 253 ? 271.072 344.450 454.725 1.00 94.02  ? 253 CYS A C   1 
ATOM 3285 O O   . CYS C 3 253 ? 270.784 343.906 453.659 1.00 94.02  ? 253 CYS A O   1 
ATOM 3286 C CB  . CYS C 3 253 ? 272.100 346.702 455.055 1.00 94.02  ? 253 CYS A CB  1 
ATOM 3287 S SG  . CYS C 3 253 ? 273.479 347.648 455.691 1.00 94.02  ? 253 CYS A SG  1 
ATOM 3288 N N   . GLN C 3 254 ? 270.266 344.424 455.778 1.00 98.70  ? 254 GLN A N   1 
ATOM 3289 C CA  . GLN C 3 254 ? 269.010 343.702 455.727 1.00 98.70  ? 254 GLN A CA  1 
ATOM 3290 C C   . GLN C 3 254 ? 267.963 344.491 454.957 1.00 98.70  ? 254 GLN A C   1 
ATOM 3291 O O   . GLN C 3 254 ? 268.163 345.648 454.586 1.00 98.70  ? 254 GLN A O   1 
ATOM 3292 C CB  . GLN C 3 254 ? 268.498 343.404 457.130 1.00 98.70  ? 254 GLN A CB  1 
ATOM 3293 C CG  . GLN C 3 254 ? 269.287 342.330 457.835 1.00 98.70  ? 254 GLN A CG  1 
ATOM 3294 C CD  . GLN C 3 254 ? 269.083 340.967 457.211 1.00 98.70  ? 254 GLN A CD  1 
ATOM 3295 O OE1 . GLN C 3 254 ? 268.016 340.673 456.674 1.00 98.70  ? 254 GLN A OE1 1 
ATOM 3296 N NE2 . GLN C 3 254 ? 270.109 340.128 457.274 1.00 98.70  ? 254 GLN A NE2 1 
ATOM 3297 N N   . TYR C 3 255 ? 266.835 343.839 454.709 1.00 96.08  ? 255 TYR A N   1 
ATOM 3298 C CA  . TYR C 3 255 ? 265.731 344.478 454.014 1.00 96.08  ? 255 TYR A CA  1 
ATOM 3299 C C   . TYR C 3 255 ? 264.700 344.954 455.020 1.00 96.08  ? 255 TYR A C   1 
ATOM 3300 O O   . TYR C 3 255 ? 264.085 344.147 455.720 1.00 96.08  ? 255 TYR A O   1 
ATOM 3301 C CB  . TYR C 3 255 ? 265.103 343.516 453.017 1.00 96.08  ? 255 TYR A CB  1 
ATOM 3302 C CG  . TYR C 3 255 ? 265.901 343.411 451.757 1.00 96.08  ? 255 TYR A CG  1 
ATOM 3303 C CD1 . TYR C 3 255 ? 265.848 344.413 450.809 1.00 96.08  ? 255 TYR A CD1 1 
ATOM 3304 C CD2 . TYR C 3 255 ? 266.722 342.323 451.520 1.00 96.08  ? 255 TYR A CD2 1 
ATOM 3305 C CE1 . TYR C 3 255 ? 266.577 344.335 449.654 1.00 96.08  ? 255 TYR A CE1 1 
ATOM 3306 C CE2 . TYR C 3 255 ? 267.461 342.233 450.365 1.00 96.08  ? 255 TYR A CE2 1 
ATOM 3307 C CZ  . TYR C 3 255 ? 267.384 343.245 449.437 1.00 96.08  ? 255 TYR A CZ  1 
ATOM 3308 O OH  . TYR C 3 255 ? 268.116 343.174 448.280 1.00 96.08  ? 255 TYR A OH  1 
ATOM 3309 N N   . GLU C 3 256 ? 264.509 346.265 455.089 1.00 103.66 ? 256 GLU A N   1 
ATOM 3310 C CA  . GLU C 3 256 ? 263.673 346.853 456.122 1.00 103.66 ? 256 GLU A CA  1 
ATOM 3311 C C   . GLU C 3 256 ? 262.267 347.166 455.637 1.00 103.66 ? 256 GLU A C   1 
ATOM 3312 O O   . GLU C 3 256 ? 261.291 346.797 456.294 1.00 103.66 ? 256 GLU A O   1 
ATOM 3313 C CB  . GLU C 3 256 ? 264.339 348.119 456.666 1.00 103.66 ? 256 GLU A CB  1 
ATOM 3314 C CG  . GLU C 3 256 ? 265.516 347.884 457.622 1.00 103.66 ? 256 GLU A CG  1 
ATOM 3315 C CD  . GLU C 3 256 ? 265.138 347.479 459.051 1.00 103.66 ? 256 GLU A CD  1 
ATOM 3316 O OE1 . GLU C 3 256 ? 264.080 346.860 459.292 1.00 103.66 ? 256 GLU A OE1 1 
ATOM 3317 O OE2 . GLU C 3 256 ? 265.931 347.789 459.962 1.00 103.66 ? 256 GLU A OE2 1 
ATOM 3318 N N   . LYS C 3 257 ? 262.137 347.839 454.505 1.00 106.58 ? 257 LYS A N   1 
ATOM 3319 C CA  . LYS C 3 257 ? 260.836 348.188 453.967 1.00 106.58 ? 257 LYS A CA  1 
ATOM 3320 C C   . LYS C 3 257 ? 260.695 347.650 452.551 1.00 106.58 ? 257 LYS A C   1 
ATOM 3321 O O   . LYS C 3 257 ? 261.667 347.253 451.909 1.00 106.58 ? 257 LYS A O   1 
ATOM 3322 C CB  . LYS C 3 257 ? 260.622 349.702 453.987 1.00 106.58 ? 257 LYS A CB  1 
ATOM 3323 C CG  . LYS C 3 257 ? 260.417 350.269 455.369 1.00 106.58 ? 257 LYS A CG  1 
ATOM 3324 C CD  . LYS C 3 257 ? 258.944 350.367 455.694 1.00 106.58 ? 257 LYS A CD  1 
ATOM 3325 C CE  . LYS C 3 257 ? 258.722 351.032 457.035 1.00 106.58 ? 257 LYS A CE  1 
ATOM 3326 N NZ  . LYS C 3 257 ? 257.279 351.283 457.287 1.00 106.58 ? 257 LYS A NZ  1 
ATOM 3327 N N   . GLN C 3 258 ? 259.459 347.648 452.065 1.00 104.66 ? 258 GLN A N   1 
ATOM 3328 C CA  . GLN C 3 258 ? 259.163 347.101 450.751 1.00 104.66 ? 258 GLN A CA  1 
ATOM 3329 C C   . GLN C 3 258 ? 259.336 348.116 449.638 1.00 104.66 ? 258 GLN A C   1 
ATOM 3330 O O   . GLN C 3 258 ? 259.822 347.767 448.559 1.00 104.66 ? 258 GLN A O   1 
ATOM 3331 C CB  . GLN C 3 258 ? 257.732 346.567 450.722 1.00 104.66 ? 258 GLN A CB  1 
ATOM 3332 C CG  . GLN C 3 258 ? 257.377 345.797 449.473 1.00 104.66 ? 258 GLN A CG  1 
ATOM 3333 C CD  . GLN C 3 258 ? 256.033 345.119 449.582 1.00 104.66 ? 258 GLN A CD  1 
ATOM 3334 O OE1 . GLN C 3 258 ? 255.158 345.310 448.739 1.00 104.66 ? 258 GLN A OE1 1 
ATOM 3335 N NE2 . GLN C 3 258 ? 255.854 344.323 450.628 1.00 104.66 ? 258 GLN A NE2 1 
ATOM 3336 N N   . LYS C 3 259 ? 258.967 349.370 449.880 1.00 107.77 ? 259 LYS A N   1 
ATOM 3337 C CA  . LYS C 3 259 ? 258.916 350.347 448.800 1.00 107.77 ? 259 LYS A CA  1 
ATOM 3338 C C   . LYS C 3 259 ? 260.300 350.857 448.435 1.00 107.77 ? 259 LYS A C   1 
ATOM 3339 O O   . LYS C 3 259 ? 260.611 351.020 447.251 1.00 107.77 ? 259 LYS A O   1 
ATOM 3340 C CB  . LYS C 3 259 ? 258.028 351.530 449.187 1.00 107.77 ? 259 LYS A CB  1 
ATOM 3341 C CG  . LYS C 3 259 ? 256.533 351.343 448.972 1.00 107.77 ? 259 LYS A CG  1 
ATOM 3342 C CD  . LYS C 3 259 ? 255.905 350.519 450.082 1.00 107.77 ? 259 LYS A CD  1 
ATOM 3343 C CE  . LYS C 3 259 ? 256.005 351.248 451.410 1.00 107.77 ? 259 LYS A CE  1 
ATOM 3344 N NZ  . LYS C 3 259 ? 255.388 350.471 452.514 1.00 107.77 ? 259 LYS A NZ  1 
ATOM 3345 N N   . ASN C 3 260 ? 261.135 351.118 449.427 1.00 104.69 ? 260 ASN A N   1 
ATOM 3346 C CA  . ASN C 3 260 ? 262.382 351.832 449.226 1.00 104.69 ? 260 ASN A CA  1 
ATOM 3347 C C   . ASN C 3 260 ? 263.570 350.980 449.668 1.00 104.69 ? 260 ASN A C   1 
ATOM 3348 O O   . ASN C 3 260 ? 263.436 349.799 449.985 1.00 104.69 ? 260 ASN A O   1 
ATOM 3349 C CB  . ASN C 3 260 ? 262.307 353.183 449.938 1.00 104.69 ? 260 ASN A CB  1 
ATOM 3350 C CG  . ASN C 3 260 ? 261.873 353.062 451.383 1.00 104.69 ? 260 ASN A CG  1 
ATOM 3351 O OD1 . ASN C 3 260 ? 261.777 351.971 451.931 1.00 104.69 ? 260 ASN A OD1 1 
ATOM 3352 N ND2 . ASN C 3 260 ? 261.571 354.194 451.995 1.00 104.69 ? 260 ASN A ND2 1 
ATOM 3353 N N   . VAL C 3 261 ? 264.743 351.602 449.688 1.00 96.99  ? 261 VAL A N   1 
ATOM 3354 C CA  . VAL C 3 261 ? 266.001 350.888 449.834 1.00 96.99  ? 261 VAL A CA  1 
ATOM 3355 C C   . VAL C 3 261 ? 266.626 351.308 451.163 1.00 96.99  ? 261 VAL A C   1 
ATOM 3356 O O   . VAL C 3 261 ? 267.841 351.206 451.374 1.00 96.99  ? 261 VAL A O   1 
ATOM 3357 C CB  . VAL C 3 261 ? 266.882 351.165 448.595 1.00 96.99  ? 261 VAL A CB  1 
ATOM 3358 C CG1 . VAL C 3 261 ? 267.388 352.608 448.553 1.00 96.99  ? 261 VAL A CG1 1 
ATOM 3359 C CG2 . VAL C 3 261 ? 267.993 350.127 448.398 1.00 96.99  ? 261 VAL A CG2 1 
ATOM 3360 N N   . ASN C 3 262 ? 265.776 351.722 452.100 1.00 98.82  ? 262 ASN A N   1 
ATOM 3361 C CA  . ASN C 3 262 ? 266.243 352.199 453.392 1.00 98.82  ? 262 ASN A CA  1 
ATOM 3362 C C   . ASN C 3 262 ? 266.852 351.070 454.206 1.00 98.82  ? 262 ASN A C   1 
ATOM 3363 O O   . ASN C 3 262 ? 266.526 349.897 454.021 1.00 98.82  ? 262 ASN A O   1 
ATOM 3364 C CB  . ASN C 3 262 ? 265.100 352.831 454.171 1.00 98.82  ? 262 ASN A CB  1 
ATOM 3365 C CG  . ASN C 3 262 ? 264.889 354.269 453.809 1.00 98.82  ? 262 ASN A CG  1 
ATOM 3366 O OD1 . ASN C 3 262 ? 265.792 354.935 453.310 1.00 98.82  ? 262 ASN A OD1 1 
ATOM 3367 N ND2 . ASN C 3 262 ? 263.697 354.772 454.074 1.00 98.82  ? 262 ASN A ND2 1 
ATOM 3368 N N   . PHE C 3 263 ? 267.763 351.433 455.098 1.00 90.81  ? 263 PHE A N   1 
ATOM 3369 C CA  . PHE C 3 263 ? 268.539 350.436 455.815 1.00 90.81  ? 263 PHE A CA  1 
ATOM 3370 C C   . PHE C 3 263 ? 269.055 351.039 457.108 1.00 90.81  ? 263 PHE A C   1 
ATOM 3371 O O   . PHE C 3 263 ? 268.895 352.230 457.372 1.00 90.81  ? 263 PHE A O   1 
ATOM 3372 C CB  . PHE C 3 263 ? 269.695 349.908 454.961 1.00 90.81  ? 263 PHE A CB  1 
ATOM 3373 C CG  . PHE C 3 263 ? 270.753 350.930 454.652 1.00 90.81  ? 263 PHE A CG  1 
ATOM 3374 C CD1 . PHE C 3 263 ? 270.590 351.824 453.616 1.00 90.81  ? 263 PHE A CD1 1 
ATOM 3375 C CD2 . PHE C 3 263 ? 271.933 350.960 455.367 1.00 90.81  ? 263 PHE A CD2 1 
ATOM 3376 C CE1 . PHE C 3 263 ? 271.563 352.748 453.326 1.00 90.81  ? 263 PHE A CE1 1 
ATOM 3377 C CE2 . PHE C 3 263 ? 272.903 351.883 455.080 1.00 90.81  ? 263 PHE A CE2 1 
ATOM 3378 C CZ  . PHE C 3 263 ? 272.717 352.776 454.060 1.00 90.81  ? 263 PHE A CZ  1 
ATOM 3379 N N   . SER C 3 264 ? 269.682 350.187 457.910 1.00 89.91  ? 264 SER A N   1 
ATOM 3380 C CA  . SER C 3 264 ? 270.422 350.575 459.088 1.00 89.91  ? 264 SER A CA  1 
ATOM 3381 C C   . SER C 3 264 ? 271.875 350.161 458.915 1.00 89.91  ? 264 SER A C   1 
ATOM 3382 O O   . SER C 3 264 ? 272.140 349.108 458.327 1.00 89.91  ? 264 SER A O   1 
ATOM 3383 C CB  . SER C 3 264 ? 269.844 349.915 460.341 1.00 89.91  ? 264 SER A CB  1 
ATOM 3384 O OG  . SER C 3 264 ? 269.545 348.557 460.087 1.00 89.91  ? 264 SER A OG  1 
ATOM 3385 N N   . PRO C 3 265 ? 272.831 350.957 459.389 1.00 85.64  ? 265 PRO A N   1 
ATOM 3386 C CA  . PRO C 3 265 ? 274.240 350.666 459.101 1.00 85.64  ? 265 PRO A CA  1 
ATOM 3387 C C   . PRO C 3 265 ? 274.727 349.467 459.893 1.00 85.64  ? 265 PRO A C   1 
ATOM 3388 O O   . PRO C 3 265 ? 274.349 349.271 461.047 1.00 85.64  ? 265 PRO A O   1 
ATOM 3389 C CB  . PRO C 3 265 ? 274.963 351.947 459.523 1.00 85.64  ? 265 PRO A CB  1 
ATOM 3390 C CG  . PRO C 3 265 ? 273.900 352.970 459.643 1.00 85.64  ? 265 PRO A CG  1 
ATOM 3391 C CD  . PRO C 3 265 ? 272.685 352.240 460.080 1.00 85.64  ? 265 PRO A CD  1 
ATOM 3392 N N   . ILE C 3 266 ? 275.567 348.659 459.253 1.00 87.64  ? 266 ILE A N   1 
ATOM 3393 C CA  . ILE C 3 266 ? 276.042 347.407 459.814 1.00 87.64  ? 266 ILE A CA  1 
ATOM 3394 C C   . ILE C 3 266 ? 277.525 347.290 459.488 1.00 87.64  ? 266 ILE A C   1 
ATOM 3395 O O   . ILE C 3 266 ? 278.043 347.979 458.608 1.00 87.64  ? 266 ILE A O   1 
ATOM 3396 C CB  . ILE C 3 266 ? 275.234 346.206 459.266 1.00 87.64  ? 266 ILE A CB  1 
ATOM 3397 C CG1 . ILE C 3 266 ? 275.247 345.021 460.229 1.00 87.64  ? 266 ILE A CG1 1 
ATOM 3398 C CG2 . ILE C 3 266 ? 275.737 345.781 457.912 1.00 87.64  ? 266 ILE A CG2 1 
ATOM 3399 C CD1 . ILE C 3 266 ? 274.392 343.864 459.767 1.00 87.64  ? 266 ILE A CD1 1 
ATOM 3400 N N   . GLY C 3 267 ? 278.218 346.446 460.245 1.00 90.81  ? 267 GLY A N   1 
ATOM 3401 C CA  . GLY C 3 267 ? 279.610 346.182 459.957 1.00 90.81  ? 267 GLY A CA  1 
ATOM 3402 C C   . GLY C 3 267 ? 279.783 345.411 458.667 1.00 90.81  ? 267 GLY A C   1 
ATOM 3403 O O   . GLY C 3 267 ? 278.867 344.758 458.173 1.00 90.81  ? 267 GLY A O   1 
ATOM 3404 N N   . VAL C 3 268 ? 280.991 345.484 458.114 1.00 92.80  ? 268 VAL A N   1 
ATOM 3405 C CA  . VAL C 3 268 ? 281.232 344.913 456.795 1.00 92.80  ? 268 VAL A CA  1 
ATOM 3406 C C   . VAL C 3 268 ? 281.292 343.395 456.857 1.00 92.80  ? 268 VAL A C   1 
ATOM 3407 O O   . VAL C 3 268 ? 280.627 342.705 456.080 1.00 92.80  ? 268 VAL A O   1 
ATOM 3408 C CB  . VAL C 3 268 ? 282.514 345.500 456.184 1.00 92.80  ? 268 VAL A CB  1 
ATOM 3409 C CG1 . VAL C 3 268 ? 282.664 345.021 454.767 1.00 92.80  ? 268 VAL A CG1 1 
ATOM 3410 C CG2 . VAL C 3 268 ? 282.455 346.998 456.212 1.00 92.80  ? 268 VAL A CG2 1 
ATOM 3411 N N   . THR C 3 269 ? 282.081 342.846 457.771 1.00 99.95  ? 269 THR A N   1 
ATOM 3412 C CA  . THR C 3 269 ? 282.263 341.407 457.849 1.00 99.95  ? 269 THR A CA  1 
ATOM 3413 C C   . THR C 3 269 ? 282.220 340.991 459.309 1.00 99.95  ? 269 THR A C   1 
ATOM 3414 O O   . THR C 3 269 ? 282.439 341.810 460.202 1.00 99.95  ? 269 THR A O   1 
ATOM 3415 C CB  . THR C 3 269 ? 283.595 340.987 457.211 1.00 99.95  ? 269 THR A CB  1 
ATOM 3416 O OG1 . THR C 3 269 ? 283.875 341.846 456.104 1.00 99.95  ? 269 THR A OG1 1 
ATOM 3417 C CG2 . THR C 3 269 ? 283.530 339.564 456.683 1.00 99.95  ? 269 THR A CG2 1 
ATOM 3418 N N   . THR C 3 270 ? 281.899 339.723 459.550 1.00 99.57  ? 270 THR A N   1 
ATOM 3419 C CA  . THR C 3 270 ? 282.069 339.163 460.880 1.00 99.57  ? 270 THR A CA  1 
ATOM 3420 C C   . THR C 3 270 ? 283.547 339.126 461.244 1.00 99.57  ? 270 THR A C   1 
ATOM 3421 O O   . THR C 3 270 ? 284.417 339.025 460.377 1.00 99.57  ? 270 THR A O   1 
ATOM 3422 C CB  . THR C 3 270 ? 281.464 337.765 460.950 1.00 99.57  ? 270 THR A CB  1 
ATOM 3423 O OG1 . THR C 3 270 ? 281.802 337.162 462.204 1.00 99.57  ? 270 THR A OG1 1 
ATOM 3424 C CG2 . THR C 3 270 ? 281.973 336.901 459.814 1.00 99.57  ? 270 THR A CG2 1 
ATOM 3425 N N   . SER C 3 271 ? 283.831 339.217 462.533 1.00 97.69  ? 271 SER A N   1 
ATOM 3426 C CA  . SER C 3 271 ? 285.173 339.524 462.992 1.00 97.69  ? 271 SER A CA  1 
ATOM 3427 C C   . SER C 3 271 ? 285.947 338.274 463.376 1.00 97.69  ? 271 SER A C   1 
ATOM 3428 O O   . SER C 3 271 ? 285.376 337.206 463.594 1.00 97.69  ? 271 SER A O   1 
ATOM 3429 C CB  . SER C 3 271 ? 285.109 340.452 464.191 1.00 97.69  ? 271 SER A CB  1 
ATOM 3430 O OG  . SER C 3 271 ? 285.003 339.704 465.384 1.00 97.69  ? 271 SER A OG  1 
ATOM 3431 N N   . ARG C 3 272 ? 287.264 338.424 463.457 1.00 92.26  ? 272 ARG A N   1 
ATOM 3432 C CA  . ARG C 3 272 ? 288.162 337.431 464.024 1.00 92.26  ? 272 ARG A CA  1 
ATOM 3433 C C   . ARG C 3 272 ? 289.005 338.099 465.101 1.00 92.26  ? 272 ARG A C   1 
ATOM 3434 O O   . ARG C 3 272 ? 288.940 339.309 465.302 1.00 92.26  ? 272 ARG A O   1 
ATOM 3435 C CB  . ARG C 3 272 ? 289.032 336.794 462.942 1.00 92.26  ? 272 ARG A CB  1 
ATOM 3436 C CG  . ARG C 3 272 ? 289.884 337.768 462.181 1.00 92.26  ? 272 ARG A CG  1 
ATOM 3437 C CD  . ARG C 3 272 ? 290.671 337.048 461.114 1.00 92.26  ? 272 ARG A CD  1 
ATOM 3438 N NE  . ARG C 3 272 ? 291.647 337.917 460.477 1.00 92.26  ? 272 ARG A NE  1 
ATOM 3439 C CZ  . ARG C 3 272 ? 292.477 337.518 459.526 1.00 92.26  ? 272 ARG A CZ  1 
ATOM 3440 N NH1 . ARG C 3 272 ? 292.443 336.267 459.110 1.00 92.26  ? 272 ARG A NH1 1 
ATOM 3441 N NH2 . ARG C 3 272 ? 293.339 338.365 458.997 1.00 92.26  ? 272 ARG A NH2 1 
ATOM 3442 N N   . THR C 3 273 ? 289.808 337.302 465.803 1.00 101.31 ? 273 THR A N   1 
ATOM 3443 C CA  . THR C 3 273 ? 290.426 337.803 467.026 1.00 101.31 ? 273 THR A CA  1 
ATOM 3444 C C   . THR C 3 273 ? 291.684 338.622 466.761 1.00 101.31 ? 273 THR A C   1 
ATOM 3445 O O   . THR C 3 273 ? 292.032 339.491 467.564 1.00 101.31 ? 273 THR A O   1 
ATOM 3446 C CB  . THR C 3 273 ? 290.741 336.648 467.972 1.00 101.31 ? 273 THR A CB  1 
ATOM 3447 O OG1 . THR C 3 273 ? 291.528 337.134 469.065 1.00 101.31 ? 273 THR A OG1 1 
ATOM 3448 C CG2 . THR C 3 273 ? 291.492 335.542 467.252 1.00 101.31 ? 273 THR A CG2 1 
ATOM 3449 N N   . ASP C 3 274 ? 292.381 338.366 465.659 1.00 101.16 ? 274 ASP A N   1 
ATOM 3450 C CA  . ASP C 3 274 ? 293.605 339.088 465.344 1.00 101.16 ? 274 ASP A CA  1 
ATOM 3451 C C   . ASP C 3 274 ? 293.790 339.124 463.834 1.00 101.16 ? 274 ASP A C   1 
ATOM 3452 O O   . ASP C 3 274 ? 292.990 338.571 463.077 1.00 101.16 ? 274 ASP A O   1 
ATOM 3453 C CB  . ASP C 3 274 ? 294.802 338.480 466.088 1.00 101.16 ? 274 ASP A CB  1 
ATOM 3454 C CG  . ASP C 3 274 ? 294.989 336.977 465.835 1.00 101.16 ? 274 ASP A CG  1 
ATOM 3455 O OD1 . ASP C 3 274 ? 294.810 336.466 464.708 1.00 101.16 ? 274 ASP A OD1 1 
ATOM 3456 O OD2 . ASP C 3 274 ? 295.335 336.280 466.810 1.00 101.16 ? 274 ASP A OD2 1 
ATOM 3457 N N   . ILE C 3 275 ? 294.860 339.779 463.394 1.00 94.72  ? 275 ILE A N   1 
ATOM 3458 C CA  . ILE C 3 275 ? 295.120 339.814 461.963 1.00 94.72  ? 275 ILE A CA  1 
ATOM 3459 C C   . ILE C 3 275 ? 295.906 338.582 461.524 1.00 94.72  ? 275 ILE A C   1 
ATOM 3460 O O   . ILE C 3 275 ? 295.700 338.075 460.417 1.00 94.72  ? 275 ILE A O   1 
ATOM 3461 C CB  . ILE C 3 275 ? 295.814 341.137 461.586 1.00 94.72  ? 275 ILE A CB  1 
ATOM 3462 C CG1 . ILE C 3 275 ? 296.030 341.245 460.079 1.00 94.72  ? 275 ILE A CG1 1 
ATOM 3463 C CG2 . ILE C 3 275 ? 297.106 341.333 462.352 1.00 94.72  ? 275 ILE A CG2 1 
ATOM 3464 C CD1 . ILE C 3 275 ? 296.440 342.609 459.639 1.00 94.72  ? 275 ILE A CD1 1 
ATOM 3465 N N   . ILE C 3 276 ? 296.762 338.041 462.383 1.00 94.06  ? 276 ILE A N   1 
ATOM 3466 C CA  . ILE C 3 276 ? 297.542 336.871 462.014 1.00 94.06  ? 276 ILE A CA  1 
ATOM 3467 C C   . ILE C 3 276 ? 296.734 335.612 462.284 1.00 94.06  ? 276 ILE A C   1 
ATOM 3468 O O   . ILE C 3 276 ? 297.157 334.510 461.946 1.00 94.06  ? 276 ILE A O   1 
ATOM 3469 C CB  . ILE C 3 276 ? 298.869 336.827 462.760 1.00 94.06  ? 276 ILE A CB  1 
ATOM 3470 C CG1 . ILE C 3 276 ? 298.636 336.463 464.220 1.00 94.06  ? 276 ILE A CG1 1 
ATOM 3471 C CG2 . ILE C 3 276 ? 299.544 338.172 462.693 1.00 94.06  ? 276 ILE A CG2 1 
ATOM 3472 C CD1 . ILE C 3 276 ? 299.898 336.121 464.959 1.00 94.06  ? 276 ILE A CD1 1 
ATOM 3473 N N   . ARG D 4 14  ? 298.273 365.298 424.692 1.00 113.53 ? 14  ARG B N   1 
ATOM 3474 C CA  . ARG D 4 14  ? 298.674 366.451 425.484 1.00 113.53 ? 14  ARG B CA  1 
ATOM 3475 C C   . ARG D 4 14  ? 298.068 367.730 424.940 1.00 113.53 ? 14  ARG B C   1 
ATOM 3476 O O   . ARG D 4 14  ? 298.038 367.931 423.725 1.00 113.53 ? 14  ARG B O   1 
ATOM 3477 C CB  . ARG D 4 14  ? 300.189 366.587 425.512 1.00 113.53 ? 14  ARG B CB  1 
ATOM 3478 C CG  . ARG D 4 14  ? 300.916 365.369 426.010 1.00 113.53 ? 14  ARG B CG  1 
ATOM 3479 C CD  . ARG D 4 14  ? 302.370 365.698 426.197 1.00 113.53 ? 14  ARG B CD  1 
ATOM 3480 N NE  . ARG D 4 14  ? 302.512 366.965 426.896 1.00 113.53 ? 14  ARG B NE  1 
ATOM 3481 C CZ  . ARG D 4 14  ? 302.641 367.069 428.209 1.00 113.53 ? 14  ARG B CZ  1 
ATOM 3482 N NH1 . ARG D 4 14  ? 302.660 365.980 428.958 1.00 113.53 ? 14  ARG B NH1 1 
ATOM 3483 N NH2 . ARG D 4 14  ? 302.759 368.261 428.772 1.00 113.53 ? 14  ARG B NH2 1 
ATOM 3484 N N   . SER D 4 15  ? 297.599 368.575 425.863 1.00 113.68 ? 15  SER B N   1 
ATOM 3485 C CA  . SER D 4 15  ? 297.061 369.910 425.588 1.00 113.68 ? 15  SER B CA  1 
ATOM 3486 C C   . SER D 4 15  ? 295.883 369.857 424.614 1.00 113.68 ? 15  SER B C   1 
ATOM 3487 O O   . SER D 4 15  ? 295.896 370.458 423.541 1.00 113.68 ? 15  SER B O   1 
ATOM 3488 C CB  . SER D 4 15  ? 298.155 370.852 425.081 1.00 113.68 ? 15  SER B CB  1 
ATOM 3489 O OG  . SER D 4 15  ? 297.610 372.113 424.749 1.00 113.68 ? 15  SER B OG  1 
ATOM 3490 N N   . ILE D 4 16  ? 294.865 369.130 425.009 1.00 109.48 ? 16  ILE B N   1 
ATOM 3491 C CA  . ILE D 4 16  ? 293.653 369.006 424.214 1.00 109.48 ? 16  ILE B CA  1 
ATOM 3492 C C   . ILE D 4 16  ? 292.796 370.237 424.429 1.00 109.48 ? 16  ILE B C   1 
ATOM 3493 O O   . ILE D 4 16  ? 292.847 370.876 425.481 1.00 109.48 ? 16  ILE B O   1 
ATOM 3494 C CB  . ILE D 4 16  ? 292.887 367.722 424.576 1.00 109.48 ? 16  ILE B CB  1 
ATOM 3495 C CG1 . ILE D 4 16  ? 292.801 367.577 426.092 1.00 109.48 ? 16  ILE B CG1 1 
ATOM 3496 C CG2 . ILE D 4 16  ? 293.560 366.522 423.954 1.00 109.48 ? 16  ILE B CG2 1 
ATOM 3497 C CD1 . ILE D 4 16  ? 292.160 366.290 426.544 1.00 109.48 ? 16  ILE B CD1 1 
ATOM 3498 N N   . THR D 4 17  ? 291.996 370.574 423.426 1.00 107.65 ? 17  THR B N   1 
ATOM 3499 C CA  . THR D 4 17  ? 291.116 371.726 423.495 1.00 107.65 ? 17  THR B CA  1 
ATOM 3500 C C   . THR D 4 17  ? 289.735 371.351 422.986 1.00 107.65 ? 17  THR B C   1 
ATOM 3501 O O   . THR D 4 17  ? 289.583 370.468 422.140 1.00 107.65 ? 17  THR B O   1 
ATOM 3502 C CB  . THR D 4 17  ? 291.669 372.910 422.692 1.00 107.65 ? 17  THR B CB  1 
ATOM 3503 O OG1 . THR D 4 17  ? 290.730 373.988 422.720 1.00 107.65 ? 17  THR B OG1 1 
ATOM 3504 C CG2 . THR D 4 17  ? 291.945 372.520 421.254 1.00 107.65 ? 17  THR B CG2 1 
ATOM 3505 N N   . LEU D 4 18  ? 288.725 372.020 423.530 1.00 101.31 ? 18  LEU B N   1 
ATOM 3506 C CA  . LEU D 4 18  ? 287.341 371.814 423.127 1.00 101.31 ? 18  LEU B CA  1 
ATOM 3507 C C   . LEU D 4 18  ? 286.611 373.132 423.281 1.00 101.31 ? 18  LEU B C   1 
ATOM 3508 O O   . LEU D 4 18  ? 286.605 373.707 424.371 1.00 101.31 ? 18  LEU B O   1 
ATOM 3509 C CB  . LEU D 4 18  ? 286.664 370.736 423.972 1.00 101.31 ? 18  LEU B CB  1 
ATOM 3510 C CG  . LEU D 4 18  ? 286.826 369.284 423.537 1.00 101.31 ? 18  LEU B CG  1 
ATOM 3511 C CD1 . LEU D 4 18  ? 285.981 368.377 424.403 1.00 101.31 ? 18  LEU B CD1 1 
ATOM 3512 C CD2 . LEU D 4 18  ? 286.449 369.138 422.081 1.00 101.31 ? 18  LEU B CD2 1 
ATOM 3513 N N   . GLY D 4 19  ? 285.997 373.604 422.202 1.00 103.98 ? 19  GLY B N   1 
ATOM 3514 C CA  . GLY D 4 19  ? 285.259 374.847 422.254 1.00 103.98 ? 19  GLY B CA  1 
ATOM 3515 C C   . GLY D 4 19  ? 286.174 376.035 422.435 1.00 103.98 ? 19  GLY B C   1 
ATOM 3516 O O   . GLY D 4 19  ? 286.893 376.420 421.511 1.00 103.98 ? 19  GLY B O   1 
ATOM 3517 N N   . ASN D 4 20  ? 286.160 376.620 423.625 1.00 102.40 ? 20  ASN B N   1 
ATOM 3518 C CA  . ASN D 4 20  ? 287.069 377.699 423.968 1.00 102.40 ? 20  ASN B CA  1 
ATOM 3519 C C   . ASN D 4 20  ? 287.729 377.427 425.303 1.00 102.40 ? 20  ASN B C   1 
ATOM 3520 O O   . ASN D 4 20  ? 288.040 378.345 426.061 1.00 102.40 ? 20  ASN B O   1 
ATOM 3521 C CB  . ASN D 4 20  ? 286.344 379.036 423.992 1.00 102.40 ? 20  ASN B CB  1 
ATOM 3522 C CG  . ASN D 4 20  ? 285.215 379.057 424.980 1.00 102.40 ? 20  ASN B CG  1 
ATOM 3523 O OD1 . ASN D 4 20  ? 284.196 378.406 424.785 1.00 102.40 ? 20  ASN B OD1 1 
ATOM 3524 N ND2 . ASN D 4 20  ? 285.385 379.815 426.051 1.00 102.40 ? 20  ASN B ND2 1 
ATOM 3525 N N   . SER D 4 21  ? 287.968 376.158 425.612 1.00 102.97 ? 21  SER B N   1 
ATOM 3526 C CA  . SER D 4 21  ? 288.624 375.793 426.854 1.00 102.97 ? 21  SER B CA  1 
ATOM 3527 C C   . SER D 4 21  ? 289.697 374.766 426.553 1.00 102.97 ? 21  SER B C   1 
ATOM 3528 O O   . SER D 4 21  ? 289.594 374.013 425.585 1.00 102.97 ? 21  SER B O   1 
ATOM 3529 C CB  . SER D 4 21  ? 287.635 375.238 427.872 1.00 102.97 ? 21  SER B CB  1 
ATOM 3530 O OG  . SER D 4 21  ? 288.303 374.881 429.064 1.00 102.97 ? 21  SER B OG  1 
ATOM 3531 N N   . THR D 4 22  ? 290.732 374.740 427.387 1.00 103.25 ? 22  THR B N   1 
ATOM 3532 C CA  . THR D 4 22  ? 291.909 373.928 427.118 1.00 103.25 ? 22  THR B CA  1 
ATOM 3533 C C   . THR D 4 22  ? 292.494 373.413 428.421 1.00 103.25 ? 22  THR B C   1 
ATOM 3534 O O   . THR D 4 22  ? 292.729 374.195 429.343 1.00 103.25 ? 22  THR B O   1 
ATOM 3535 C CB  . THR D 4 22  ? 292.960 374.742 426.360 1.00 103.25 ? 22  THR B CB  1 
ATOM 3536 O OG1 . THR D 4 22  ? 292.424 375.160 425.102 1.00 103.25 ? 22  THR B OG1 1 
ATOM 3537 C CG2 . THR D 4 22  ? 294.204 373.923 426.112 1.00 103.25 ? 22  THR B CG2 1 
ATOM 3538 N N   . ILE D 4 23  ? 292.725 372.105 428.497 1.00 102.92 ? 23  ILE B N   1 
ATOM 3539 C CA  . ILE D 4 23  ? 293.396 371.511 429.644 1.00 102.92 ? 23  ILE B CA  1 
ATOM 3540 C C   . ILE D 4 23  ? 294.670 370.837 429.168 1.00 102.92 ? 23  ILE B C   1 
ATOM 3541 O O   . ILE D 4 23  ? 294.927 370.763 427.964 1.00 102.92 ? 23  ILE B O   1 
ATOM 3542 C CB  . ILE D 4 23  ? 292.495 370.501 430.362 1.00 102.92 ? 23  ILE B CB  1 
ATOM 3543 C CG1 . ILE D 4 23  ? 291.919 369.532 429.342 1.00 102.92 ? 23  ILE B CG1 1 
ATOM 3544 C CG2 . ILE D 4 23  ? 291.396 371.219 431.097 1.00 102.92 ? 23  ILE B CG2 1 
ATOM 3545 C CD1 . ILE D 4 23  ? 290.997 368.525 429.937 1.00 102.92 ? 23  ILE B CD1 1 
ATOM 3546 N N   . THR D 4 24  ? 295.477 370.346 430.107 1.00 109.44 ? 24  THR B N   1 
ATOM 3547 C CA  . THR D 4 24  ? 296.721 369.649 429.801 1.00 109.44 ? 24  THR B CA  1 
ATOM 3548 C C   . THR D 4 24  ? 296.687 368.261 430.420 1.00 109.44 ? 24  THR B C   1 
ATOM 3549 O O   . THR D 4 24  ? 296.457 368.127 431.624 1.00 109.44 ? 24  THR B O   1 
ATOM 3550 C CB  . THR D 4 24  ? 297.941 370.403 430.338 1.00 109.44 ? 24  THR B CB  1 
ATOM 3551 O OG1 . THR D 4 24  ? 298.037 370.191 431.751 1.00 109.44 ? 24  THR B OG1 1 
ATOM 3552 C CG2 . THR D 4 24  ? 297.851 371.895 430.058 1.00 109.44 ? 24  THR B CG2 1 
ATOM 3553 N N   . THR D 4 25  ? 296.909 367.236 429.605 1.00 112.28 ? 25  THR B N   1 
ATOM 3554 C CA  . THR D 4 25  ? 296.983 365.851 430.060 1.00 112.28 ? 25  THR B CA  1 
ATOM 3555 C C   . THR D 4 25  ? 298.352 365.271 429.710 1.00 112.28 ? 25  THR B C   1 
ATOM 3556 O O   . THR D 4 25  ? 299.253 365.980 429.261 1.00 112.28 ? 25  THR B O   1 
ATOM 3557 C CB  . THR D 4 25  ? 295.873 364.999 429.441 1.00 112.28 ? 25  THR B CB  1 
ATOM 3558 O OG1 . THR D 4 25  ? 296.233 364.657 428.098 1.00 112.28 ? 25  THR B OG1 1 
ATOM 3559 C CG2 . THR D 4 25  ? 294.541 365.731 429.435 1.00 112.28 ? 25  THR B CG2 1 
ATOM 3560 N N   . GLN D 4 26  ? 298.504 363.965 429.914 1.00 107.36 ? 26  GLN B N   1 
ATOM 3561 C CA  . GLN D 4 26  ? 299.723 363.270 429.508 1.00 107.36 ? 26  GLN B CA  1 
ATOM 3562 C C   . GLN D 4 26  ? 299.554 362.563 428.170 1.00 107.36 ? 26  GLN B C   1 
ATOM 3563 O O   . GLN D 4 26  ? 300.159 361.517 427.931 1.00 107.36 ? 26  GLN B O   1 
ATOM 3564 C CB  . GLN D 4 26  ? 300.145 362.255 430.563 1.00 107.36 ? 26  GLN B CB  1 
ATOM 3565 C CG  . GLN D 4 26  ? 300.984 362.832 431.669 1.00 107.36 ? 26  GLN B CG  1 
ATOM 3566 C CD  . GLN D 4 26  ? 300.162 363.145 432.889 1.00 107.36 ? 26  GLN B CD  1 
ATOM 3567 O OE1 . GLN D 4 26  ? 298.970 363.427 432.788 1.00 107.36 ? 26  GLN B OE1 1 
ATOM 3568 N NE2 . GLN D 4 26  ? 300.788 363.087 434.057 1.00 107.36 ? 26  GLN B NE2 1 
ATOM 3569 N N   . ASN D 4 30  ? 296.290 357.117 430.147 1.00 98.78  ? 30  ASN B N   1 
ATOM 3570 C CA  . ASN D 4 30  ? 295.472 355.917 430.271 1.00 98.78  ? 30  ASN B CA  1 
ATOM 3571 C C   . ASN D 4 30  ? 294.021 356.270 430.558 1.00 98.78  ? 30  ASN B C   1 
ATOM 3572 O O   . ASN D 4 30  ? 293.727 356.930 431.550 1.00 98.78  ? 30  ASN B O   1 
ATOM 3573 C CB  . ASN D 4 30  ? 296.012 355.014 431.373 1.00 98.78  ? 30  ASN B CB  1 
ATOM 3574 C CG  . ASN D 4 30  ? 295.572 353.583 431.213 1.00 98.78  ? 30  ASN B CG  1 
ATOM 3575 O OD1 . ASN D 4 30  ? 294.810 353.254 430.306 1.00 98.78  ? 30  ASN B OD1 1 
ATOM 3576 N ND2 . ASN D 4 30  ? 296.046 352.717 432.097 1.00 98.78  ? 30  ASN B ND2 1 
ATOM 3577 N N   . VAL D 4 31  ? 293.115 355.818 429.697 1.00 90.79  ? 31  VAL B N   1 
ATOM 3578 C CA  . VAL D 4 31  ? 291.697 356.130 429.803 1.00 90.79  ? 31  VAL B CA  1 
ATOM 3579 C C   . VAL D 4 31  ? 290.905 354.828 429.790 1.00 90.79  ? 31  VAL B C   1 
ATOM 3580 O O   . VAL D 4 31  ? 291.183 353.927 428.991 1.00 90.79  ? 31  VAL B O   1 
ATOM 3581 C CB  . VAL D 4 31  ? 291.253 357.103 428.689 1.00 90.79  ? 31  VAL B CB  1 
ATOM 3582 C CG1 . VAL D 4 31  ? 291.644 356.608 427.310 1.00 90.79  ? 31  VAL B CG1 1 
ATOM 3583 C CG2 . VAL D 4 31  ? 289.768 357.355 428.741 1.00 90.79  ? 31  VAL B CG2 1 
ATOM 3584 N N   . VAL D 4 32  ? 289.967 354.699 430.724 1.00 83.37  ? 32  VAL B N   1 
ATOM 3585 C CA  . VAL D 4 32  ? 289.054 353.567 430.774 1.00 83.37  ? 32  VAL B CA  1 
ATOM 3586 C C   . VAL D 4 32  ? 287.688 354.032 430.289 1.00 83.37  ? 32  VAL B C   1 
ATOM 3587 O O   . VAL D 4 32  ? 287.155 355.042 430.761 1.00 83.37  ? 32  VAL B O   1 
ATOM 3588 C CB  . VAL D 4 32  ? 289.004 352.944 432.180 1.00 83.37  ? 32  VAL B CB  1 
ATOM 3589 C CG1 . VAL D 4 32  ? 288.809 353.980 433.254 1.00 83.37  ? 32  VAL B CG1 1 
ATOM 3590 C CG2 . VAL D 4 32  ? 287.894 351.929 432.264 1.00 83.37  ? 32  VAL B CG2 1 
ATOM 3591 N N   . VAL D 4 33  ? 287.139 353.332 429.306 1.00 84.49  ? 33  VAL B N   1 
ATOM 3592 C CA  . VAL D 4 33  ? 285.915 353.755 428.644 1.00 84.49  ? 33  VAL B CA  1 
ATOM 3593 C C   . VAL D 4 33  ? 284.790 352.793 429.007 1.00 84.49  ? 33  VAL B C   1 
ATOM 3594 O O   . VAL D 4 33  ? 284.826 351.610 428.647 1.00 84.49  ? 33  VAL B O   1 
ATOM 3595 C CB  . VAL D 4 33  ? 286.112 353.898 427.124 1.00 84.49  ? 33  VAL B CB  1 
ATOM 3596 C CG1 . VAL D 4 33  ? 286.891 352.734 426.525 1.00 84.49  ? 33  VAL B CG1 1 
ATOM 3597 C CG2 . VAL D 4 33  ? 284.785 354.042 426.443 1.00 84.49  ? 33  VAL B CG2 1 
ATOM 3598 N N   . GLY D 4 34  ? 283.843 353.302 429.800 1.00 81.30  ? 34  GLY B N   1 
ATOM 3599 C CA  . GLY D 4 34  ? 282.519 352.760 430.062 1.00 81.30  ? 34  GLY B CA  1 
ATOM 3600 C C   . GLY D 4 34  ? 282.328 351.267 430.176 1.00 81.30  ? 34  GLY B C   1 
ATOM 3601 O O   . GLY D 4 34  ? 283.108 350.575 430.831 1.00 81.30  ? 34  GLY B O   1 
ATOM 3602 N N   . TYR D 4 35  ? 281.294 350.764 429.511 1.00 78.23  ? 35  TYR B N   1 
ATOM 3603 C CA  . TYR D 4 35  ? 281.055 349.336 429.398 1.00 78.23  ? 35  TYR B CA  1 
ATOM 3604 C C   . TYR D 4 35  ? 281.486 348.800 428.046 1.00 78.23  ? 35  TYR B C   1 
ATOM 3605 O O   . TYR D 4 35  ? 280.865 347.877 427.515 1.00 78.23  ? 35  TYR B O   1 
ATOM 3606 C CB  . TYR D 4 35  ? 279.587 349.031 429.659 1.00 78.23  ? 35  TYR B CB  1 
ATOM 3607 C CG  . TYR D 4 35  ? 279.242 349.152 431.111 1.00 78.23  ? 35  TYR B CG  1 
ATOM 3608 C CD1 . TYR D 4 35  ? 279.432 348.087 431.968 1.00 78.23  ? 35  TYR B CD1 1 
ATOM 3609 C CD2 . TYR D 4 35  ? 278.758 350.337 431.630 1.00 78.23  ? 35  TYR B CD2 1 
ATOM 3610 C CE1 . TYR D 4 35  ? 279.134 348.190 433.295 1.00 78.23  ? 35  TYR B CE1 1 
ATOM 3611 C CE2 . TYR D 4 35  ? 278.457 350.449 432.957 1.00 78.23  ? 35  TYR B CE2 1 
ATOM 3612 C CZ  . TYR D 4 35  ? 278.647 349.371 433.783 1.00 78.23  ? 35  TYR B CZ  1 
ATOM 3613 O OH  . TYR D 4 35  ? 278.357 349.468 435.116 1.00 78.23  ? 35  TYR B OH  1 
ATOM 3614 N N   . GLY D 4 36  ? 282.535 349.372 427.476 1.00 87.33  ? 36  GLY B N   1 
ATOM 3615 C CA  . GLY D 4 36  ? 283.061 348.939 426.206 1.00 87.33  ? 36  GLY B CA  1 
ATOM 3616 C C   . GLY D 4 36  ? 282.584 349.739 425.017 1.00 87.33  ? 36  GLY B C   1 
ATOM 3617 O O   . GLY D 4 36  ? 283.125 349.562 423.923 1.00 87.33  ? 36  GLY B O   1 
ATOM 3618 N N   . VAL D 4 37  ? 281.601 350.612 425.191 1.00 93.92  ? 37  VAL B N   1 
ATOM 3619 C CA  . VAL D 4 37  ? 281.052 351.370 424.078 1.00 93.92  ? 37  VAL B CA  1 
ATOM 3620 C C   . VAL D 4 37  ? 281.471 352.823 424.208 1.00 93.92  ? 37  VAL B C   1 
ATOM 3621 O O   . VAL D 4 37  ? 281.783 353.313 425.297 1.00 93.92  ? 37  VAL B O   1 
ATOM 3622 C CB  . VAL D 4 37  ? 279.518 351.240 423.994 1.00 93.92  ? 37  VAL B CB  1 
ATOM 3623 C CG1 . VAL D 4 37  ? 279.123 349.783 423.983 1.00 93.92  ? 37  VAL B CG1 1 
ATOM 3624 C CG2 . VAL D 4 37  ? 278.853 351.944 425.144 1.00 93.92  ? 37  VAL B CG2 1 
ATOM 3625 N N   . TRP D 4 38  ? 281.506 353.504 423.077 1.00 101.49 ? 38  TRP B N   1 
ATOM 3626 C CA  . TRP D 4 38  ? 281.836 354.912 422.930 1.00 101.49 ? 38  TRP B CA  1 
ATOM 3627 C C   . TRP D 4 38  ? 280.555 355.723 422.785 1.00 101.49 ? 38  TRP B C   1 
ATOM 3628 O O   . TRP D 4 38  ? 279.596 355.251 422.176 1.00 101.49 ? 38  TRP B O   1 
ATOM 3629 C CB  . TRP D 4 38  ? 282.720 355.124 421.709 1.00 101.49 ? 38  TRP B CB  1 
ATOM 3630 C CG  . TRP D 4 38  ? 283.573 356.332 421.797 1.00 101.49 ? 38  TRP B CG  1 
ATOM 3631 C CD1 . TRP D 4 38  ? 283.323 357.550 421.244 1.00 101.49 ? 38  TRP B CD1 1 
ATOM 3632 C CD2 . TRP D 4 38  ? 284.814 356.452 422.488 1.00 101.49 ? 38  TRP B CD2 1 
ATOM 3633 N NE1 . TRP D 4 38  ? 284.334 358.424 421.547 1.00 101.49 ? 38  TRP B NE1 1 
ATOM 3634 C CE2 . TRP D 4 38  ? 285.263 357.772 422.311 1.00 101.49 ? 38  TRP B CE2 1 
ATOM 3635 C CE3 . TRP D 4 38  ? 285.593 355.571 423.236 1.00 101.49 ? 38  TRP B CE3 1 
ATOM 3636 C CZ2 . TRP D 4 38  ? 286.452 358.232 422.855 1.00 101.49 ? 38  TRP B CZ2 1 
ATOM 3637 C CZ3 . TRP D 4 38  ? 286.771 356.029 423.777 1.00 101.49 ? 38  TRP B CZ3 1 
ATOM 3638 C CH2 . TRP D 4 38  ? 287.190 357.347 423.584 1.00 101.49 ? 38  TRP B CH2 1 
ATOM 3639 N N   . PRO D 4 39  ? 280.494 356.927 423.350 1.00 101.69 ? 39  PRO B N   1 
ATOM 3640 C CA  . PRO D 4 39  ? 279.265 357.724 423.257 1.00 101.69 ? 39  PRO B CA  1 
ATOM 3641 C C   . PRO D 4 39  ? 279.052 358.248 421.847 1.00 101.69 ? 39  PRO B C   1 
ATOM 3642 O O   . PRO D 4 39  ? 279.936 358.873 421.262 1.00 101.69 ? 39  PRO B O   1 
ATOM 3643 C CB  . PRO D 4 39  ? 279.508 358.865 424.247 1.00 101.69 ? 39  PRO B CB  1 
ATOM 3644 C CG  . PRO D 4 39  ? 280.566 358.365 425.139 1.00 101.69 ? 39  PRO B CG  1 
ATOM 3645 C CD  . PRO D 4 39  ? 281.444 357.524 424.293 1.00 101.69 ? 39  PRO B CD  1 
ATOM 3646 N N   . GLU D 4 40  ? 277.865 357.991 421.307 1.00 112.49 ? 40  GLU B N   1 
ATOM 3647 C CA  . GLU D 4 40  ? 277.551 358.330 419.929 1.00 112.49 ? 40  GLU B CA  1 
ATOM 3648 C C   . GLU D 4 40  ? 276.093 358.759 419.846 1.00 112.49 ? 40  GLU B C   1 
ATOM 3649 O O   . GLU D 4 40  ? 275.331 358.634 420.807 1.00 112.49 ? 40  GLU B O   1 
ATOM 3650 C CB  . GLU D 4 40  ? 277.853 357.139 419.003 1.00 112.49 ? 40  GLU B CB  1 
ATOM 3651 C CG  . GLU D 4 40  ? 276.717 356.128 418.776 1.00 112.49 ? 40  GLU B CG  1 
ATOM 3652 C CD  . GLU D 4 40  ? 276.390 355.227 419.967 1.00 112.49 ? 40  GLU B CD  1 
ATOM 3653 O OE1 . GLU D 4 40  ? 276.929 355.410 421.078 1.00 112.49 ? 40  GLU B OE1 1 
ATOM 3654 O OE2 . GLU D 4 40  ? 275.564 354.308 419.783 1.00 112.49 ? 40  GLU B OE2 1 
ATOM 3655 N N   . TYR D 4 41  ? 275.703 359.258 418.675 1.00 109.87 ? 41  TYR B N   1 
ATOM 3656 C CA  . TYR D 4 41  ? 274.357 359.761 418.442 1.00 109.87 ? 41  TYR B CA  1 
ATOM 3657 C C   . TYR D 4 41  ? 273.365 358.603 418.331 1.00 109.87 ? 41  TYR B C   1 
ATOM 3658 O O   . TYR D 4 41  ? 273.699 357.433 418.527 1.00 109.87 ? 41  TYR B O   1 
ATOM 3659 C CB  . TYR D 4 41  ? 274.341 360.626 417.189 1.00 109.87 ? 41  TYR B CB  1 
ATOM 3660 C CG  . TYR D 4 41  ? 274.976 361.979 417.362 1.00 109.87 ? 41  TYR B CG  1 
ATOM 3661 C CD1 . TYR D 4 41  ? 274.252 363.044 417.867 1.00 109.87 ? 41  TYR B CD1 1 
ATOM 3662 C CD2 . TYR D 4 41  ? 276.301 362.191 417.021 1.00 109.87 ? 41  TYR B CD2 1 
ATOM 3663 C CE1 . TYR D 4 41  ? 274.825 364.283 418.025 1.00 109.87 ? 41  TYR B CE1 1 
ATOM 3664 C CE2 . TYR D 4 41  ? 276.884 363.428 417.178 1.00 109.87 ? 41  TYR B CE2 1 
ATOM 3665 C CZ  . TYR D 4 41  ? 276.140 364.470 417.681 1.00 109.87 ? 41  TYR B CZ  1 
ATOM 3666 O OH  . TYR D 4 41  ? 276.709 365.708 417.843 1.00 109.87 ? 41  TYR B OH  1 
ATOM 3667 N N   . LEU D 4 42  ? 272.120 358.918 418.001 1.00 98.52  ? 42  LEU B N   1 
ATOM 3668 C CA  . LEU D 4 42  ? 271.103 357.891 417.841 1.00 98.52  ? 42  LEU B CA  1 
ATOM 3669 C C   . LEU D 4 42  ? 271.259 357.161 416.513 1.00 98.52  ? 42  LEU B C   1 
ATOM 3670 O O   . LEU D 4 42  ? 270.504 357.394 415.572 1.00 98.52  ? 42  LEU B O   1 
ATOM 3671 C CB  . LEU D 4 42  ? 269.712 358.500 417.946 1.00 98.52  ? 42  LEU B CB  1 
ATOM 3672 C CG  . LEU D 4 42  ? 269.107 358.442 419.344 1.00 98.52  ? 42  LEU B CG  1 
ATOM 3673 C CD1 . LEU D 4 42  ? 267.873 359.313 419.431 1.00 98.52  ? 42  LEU B CD1 1 
ATOM 3674 C CD2 . LEU D 4 42  ? 268.778 357.010 419.697 1.00 98.52  ? 42  LEU B CD2 1 
ATOM 3675 N N   . ASP D 4 51  ? 258.723 362.712 417.790 1.00 123.27 ? 51  ASP B N   1 
ATOM 3676 C CA  . ASP D 4 51  ? 259.063 363.965 417.130 1.00 123.27 ? 51  ASP B CA  1 
ATOM 3677 C C   . ASP D 4 51  ? 260.503 363.941 416.645 1.00 123.27 ? 51  ASP B C   1 
ATOM 3678 O O   . ASP D 4 51  ? 261.073 362.873 416.451 1.00 123.27 ? 51  ASP B O   1 
ATOM 3679 C CB  . ASP D 4 51  ? 258.824 365.157 418.065 1.00 123.27 ? 51  ASP B CB  1 
ATOM 3680 C CG  . ASP D 4 51  ? 259.244 364.882 419.500 1.00 123.27 ? 51  ASP B CG  1 
ATOM 3681 O OD1 . ASP D 4 51  ? 259.903 363.853 419.753 1.00 123.27 ? 51  ASP B OD1 1 
ATOM 3682 O OD2 . ASP D 4 51  ? 258.903 365.696 420.382 1.00 123.27 ? 51  ASP B OD2 1 
ATOM 3683 N N   . GLN D 4 52  ? 261.086 365.112 416.447 1.00 127.29 ? 52  GLN B N   1 
ATOM 3684 C CA  . GLN D 4 52  ? 262.433 365.120 415.916 1.00 127.29 ? 52  GLN B CA  1 
ATOM 3685 C C   . GLN D 4 52  ? 263.409 365.778 416.890 1.00 127.29 ? 52  GLN B C   1 
ATOM 3686 O O   . GLN D 4 52  ? 263.040 366.693 417.631 1.00 127.29 ? 52  GLN B O   1 
ATOM 3687 C CB  . GLN D 4 52  ? 262.477 365.835 414.560 1.00 127.29 ? 52  GLN B CB  1 
ATOM 3688 C CG  . GLN D 4 52  ? 262.268 367.349 414.575 1.00 127.29 ? 52  GLN B CG  1 
ATOM 3689 C CD  . GLN D 4 52  ? 260.807 367.771 414.637 1.00 127.29 ? 52  GLN B CD  1 
ATOM 3690 O OE1 . GLN D 4 52  ? 259.999 367.185 415.357 1.00 127.29 ? 52  GLN B OE1 1 
ATOM 3691 N NE2 . GLN D 4 52  ? 260.465 368.803 413.875 1.00 127.29 ? 52  GLN B NE2 1 
ATOM 3692 N N   . PRO D 4 53  ? 264.642 365.289 416.956 1.00 123.71 ? 53  PRO B N   1 
ATOM 3693 C CA  . PRO D 4 53  ? 265.636 365.907 417.833 1.00 123.71 ? 53  PRO B CA  1 
ATOM 3694 C C   . PRO D 4 53  ? 266.533 366.897 417.108 1.00 123.71 ? 53  PRO B C   1 
ATOM 3695 O O   . PRO D 4 53  ? 266.743 366.819 415.896 1.00 123.71 ? 53  PRO B O   1 
ATOM 3696 C CB  . PRO D 4 53  ? 266.444 364.705 418.328 1.00 123.71 ? 53  PRO B CB  1 
ATOM 3697 C CG  . PRO D 4 53  ? 266.403 363.762 417.196 1.00 123.71 ? 53  PRO B CG  1 
ATOM 3698 C CD  . PRO D 4 53  ? 265.091 363.971 416.478 1.00 123.71 ? 53  PRO B CD  1 
ATOM 3699 N N   . THR D 4 54  ? 267.068 367.839 417.877 1.00 120.42 ? 54  THR B N   1 
ATOM 3700 C CA  . THR D 4 54  ? 268.119 368.735 417.419 1.00 120.42 ? 54  THR B CA  1 
ATOM 3701 C C   . THR D 4 54  ? 269.402 368.432 418.182 1.00 120.42 ? 54  THR B C   1 
ATOM 3702 O O   . THR D 4 54  ? 269.366 367.982 419.328 1.00 120.42 ? 54  THR B O   1 
ATOM 3703 C CB  . THR D 4 54  ? 267.735 370.204 417.614 1.00 120.42 ? 54  THR B CB  1 
ATOM 3704 O OG1 . THR D 4 54  ? 267.978 370.590 418.970 1.00 120.42 ? 54  THR B OG1 1 
ATOM 3705 C CG2 . THR D 4 54  ? 266.270 370.426 417.294 1.00 120.42 ? 54  THR B CG2 1 
ATOM 3706 N N   . GLN D 4 55  ? 270.543 368.669 417.535 1.00 119.91 ? 55  GLN B N   1 
ATOM 3707 C CA  . GLN D 4 55  ? 271.847 368.327 418.101 1.00 119.91 ? 55  GLN B CA  1 
ATOM 3708 C C   . GLN D 4 55  ? 272.731 369.564 418.164 1.00 119.91 ? 55  GLN B C   1 
ATOM 3709 O O   . GLN D 4 55  ? 273.355 369.939 417.161 1.00 119.91 ? 55  GLN B O   1 
ATOM 3710 C CB  . GLN D 4 55  ? 272.534 367.233 417.288 1.00 119.91 ? 55  GLN B CB  1 
ATOM 3711 C CG  . GLN D 4 55  ? 271.724 365.962 417.109 1.00 119.91 ? 55  GLN B CG  1 
ATOM 3712 C CD  . GLN D 4 55  ? 270.892 365.964 415.842 1.00 119.91 ? 55  GLN B CD  1 
ATOM 3713 O OE1 . GLN D 4 55  ? 270.194 366.930 415.543 1.00 119.91 ? 55  GLN B OE1 1 
ATOM 3714 N NE2 . GLN D 4 55  ? 270.958 364.870 415.091 1.00 119.91 ? 55  GLN B NE2 1 
ATOM 3715 N N   . PRO D 4 56  ? 272.821 370.228 419.315 1.00 123.23 ? 56  PRO B N   1 
ATOM 3716 C CA  . PRO D 4 56  ? 273.772 371.334 419.459 1.00 123.23 ? 56  PRO B CA  1 
ATOM 3717 C C   . PRO D 4 56  ? 275.125 370.860 419.965 1.00 123.23 ? 56  PRO B C   1 
ATOM 3718 O O   . PRO D 4 56  ? 275.234 370.034 420.873 1.00 123.23 ? 56  PRO B O   1 
ATOM 3719 C CB  . PRO D 4 56  ? 273.089 372.248 420.484 1.00 123.23 ? 56  PRO B CB  1 
ATOM 3720 C CG  . PRO D 4 56  ? 272.278 371.339 421.301 1.00 123.23 ? 56  PRO B CG  1 
ATOM 3721 C CD  . PRO D 4 56  ? 271.924 370.124 420.475 1.00 123.23 ? 56  PRO B CD  1 
ATOM 3722 N N   . ASP D 4 57  ? 276.175 371.397 419.349 1.00 131.08 ? 57  ASP B N   1 
ATOM 3723 C CA  . ASP D 4 57  ? 277.530 370.927 419.590 1.00 131.08 ? 57  ASP B CA  1 
ATOM 3724 C C   . ASP D 4 57  ? 278.554 372.025 419.798 1.00 131.08 ? 57  ASP B C   1 
ATOM 3725 O O   . ASP D 4 57  ? 279.575 371.770 420.446 1.00 131.08 ? 57  ASP B O   1 
ATOM 3726 C CB  . ASP D 4 57  ? 277.992 370.052 418.420 1.00 131.08 ? 57  ASP B CB  1 
ATOM 3727 C CG  . ASP D 4 57  ? 277.668 370.672 417.073 1.00 131.08 ? 57  ASP B CG  1 
ATOM 3728 O OD1 . ASP D 4 57  ? 277.194 371.828 417.039 1.00 131.08 ? 57  ASP B OD1 1 
ATOM 3729 O OD2 . ASP D 4 57  ? 277.877 369.999 416.044 1.00 131.08 ? 57  ASP B OD2 1 
ATOM 3730 N N   . VAL D 4 58  ? 278.326 373.230 419.284 1.00 135.15 ? 58  VAL B N   1 
ATOM 3731 C CA  . VAL D 4 58  ? 279.369 374.247 419.313 1.00 135.15 ? 58  VAL B CA  1 
ATOM 3732 C C   . VAL D 4 58  ? 279.403 374.931 420.674 1.00 135.15 ? 58  VAL B C   1 
ATOM 3733 O O   . VAL D 4 58  ? 280.400 375.559 421.050 1.00 135.15 ? 58  VAL B O   1 
ATOM 3734 C CB  . VAL D 4 58  ? 279.166 375.250 418.156 1.00 135.15 ? 58  VAL B CB  1 
ATOM 3735 C CG1 . VAL D 4 58  ? 278.054 376.251 418.459 1.00 135.15 ? 58  VAL B CG1 1 
ATOM 3736 C CG2 . VAL D 4 58  ? 280.474 375.959 417.798 1.00 135.15 ? 58  VAL B CG2 1 
ATOM 3737 N N   . ALA D 4 59  ? 278.333 374.799 421.445 1.00 123.79 ? 59  ALA B N   1 
ATOM 3738 C CA  . ALA D 4 59  ? 278.202 375.577 422.663 1.00 123.79 ? 59  ALA B CA  1 
ATOM 3739 C C   . ALA D 4 59  ? 278.072 374.728 423.917 1.00 123.79 ? 59  ALA B C   1 
ATOM 3740 O O   . ALA D 4 59  ? 278.026 375.284 425.018 1.00 123.79 ? 59  ALA B O   1 
ATOM 3741 C CB  . ALA D 4 59  ? 277.001 376.512 422.548 1.00 123.79 ? 59  ALA B CB  1 
ATOM 3742 N N   . THR D 4 60  ? 278.007 373.409 423.791 1.00 114.75 ? 60  THR B N   1 
ATOM 3743 C CA  . THR D 4 60  ? 277.935 372.543 424.959 1.00 114.75 ? 60  THR B CA  1 
ATOM 3744 C C   . THR D 4 60  ? 279.173 371.690 425.149 1.00 114.75 ? 60  THR B C   1 
ATOM 3745 O O   . THR D 4 60  ? 279.446 371.258 426.265 1.00 114.75 ? 60  THR B O   1 
ATOM 3746 C CB  . THR D 4 60  ? 276.714 371.626 424.876 1.00 114.75 ? 60  THR B CB  1 
ATOM 3747 O OG1 . THR D 4 60  ? 276.946 370.616 423.890 1.00 114.75 ? 60  THR B OG1 1 
ATOM 3748 C CG2 . THR D 4 60  ? 275.474 372.413 424.511 1.00 114.75 ? 60  THR B CG2 1 
ATOM 3749 N N   . CYS D 4 61  ? 279.930 371.431 424.090 1.00 108.13 ? 61  CYS B N   1 
ATOM 3750 C CA  . CYS D 4 61  ? 281.089 370.551 424.187 1.00 108.13 ? 61  CYS B CA  1 
ATOM 3751 C C   . CYS D 4 61  ? 282.288 371.366 424.649 1.00 108.13 ? 61  CYS B C   1 
ATOM 3752 O O   . CYS D 4 61  ? 283.133 371.773 423.856 1.00 108.13 ? 61  CYS B O   1 
ATOM 3753 C CB  . CYS D 4 61  ? 281.356 369.873 422.851 1.00 108.13 ? 61  CYS B CB  1 
ATOM 3754 S SG  . CYS D 4 61  ? 282.262 368.317 422.971 1.00 108.13 ? 61  CYS B SG  1 
ATOM 3755 N N   . ARG D 4 62  ? 282.366 371.606 425.953 1.00 93.91  ? 62  ARG B N   1 
ATOM 3756 C CA  . ARG D 4 62  ? 283.519 372.264 426.541 1.00 93.91  ? 62  ARG B CA  1 
ATOM 3757 C C   . ARG D 4 62  ? 283.709 371.731 427.950 1.00 93.91  ? 62  ARG B C   1 
ATOM 3758 O O   . ARG D 4 62  ? 282.868 371.002 428.474 1.00 93.91  ? 62  ARG B O   1 
ATOM 3759 C CB  . ARG D 4 62  ? 283.361 373.780 426.541 1.00 93.91  ? 62  ARG B CB  1 
ATOM 3760 C CG  . ARG D 4 62  ? 282.197 374.272 427.350 1.00 93.91  ? 62  ARG B CG  1 
ATOM 3761 C CD  . ARG D 4 62  ? 282.011 375.761 427.165 1.00 93.91  ? 62  ARG B CD  1 
ATOM 3762 N NE  . ARG D 4 62  ? 283.195 376.502 427.566 1.00 93.91  ? 62  ARG B NE  1 
ATOM 3763 C CZ  . ARG D 4 62  ? 283.390 376.973 428.788 1.00 93.91  ? 62  ARG B CZ  1 
ATOM 3764 N NH1 . ARG D 4 62  ? 282.476 376.778 429.719 1.00 93.91  ? 62  ARG B NH1 1 
ATOM 3765 N NH2 . ARG D 4 62  ? 284.494 377.636 429.079 1.00 93.91  ? 62  ARG B NH2 1 
ATOM 3766 N N   . PHE D 4 63  ? 284.825 372.098 428.564 1.00 91.41  ? 63  PHE B N   1 
ATOM 3767 C CA  . PHE D 4 63  ? 285.219 371.538 429.851 1.00 91.41  ? 63  PHE B CA  1 
ATOM 3768 C C   . PHE D 4 63  ? 284.704 372.423 430.976 1.00 91.41  ? 63  PHE B C   1 
ATOM 3769 O O   . PHE D 4 63  ? 285.250 373.499 431.223 1.00 91.41  ? 63  PHE B O   1 
ATOM 3770 C CB  . PHE D 4 63  ? 286.734 371.401 429.928 1.00 91.41  ? 63  PHE B CB  1 
ATOM 3771 C CG  . PHE D 4 63  ? 287.290 370.351 429.027 1.00 91.41  ? 63  PHE B CG  1 
ATOM 3772 C CD1 . PHE D 4 63  ? 287.191 369.017 429.360 1.00 91.41  ? 63  PHE B CD1 1 
ATOM 3773 C CD2 . PHE D 4 63  ? 287.923 370.696 427.853 1.00 91.41  ? 63  PHE B CD2 1 
ATOM 3774 C CE1 . PHE D 4 63  ? 287.702 368.047 428.537 1.00 91.41  ? 63  PHE B CE1 1 
ATOM 3775 C CE2 . PHE D 4 63  ? 288.438 369.729 427.025 1.00 91.41  ? 63  PHE B CE2 1 
ATOM 3776 C CZ  . PHE D 4 63  ? 288.328 368.404 427.370 1.00 91.41  ? 63  PHE B CZ  1 
ATOM 3777 N N   . TYR D 4 64  ? 283.672 371.968 431.675 1.00 87.38  ? 64  TYR B N   1 
ATOM 3778 C CA  . TYR D 4 64  ? 283.137 372.699 432.818 1.00 87.38  ? 64  TYR B CA  1 
ATOM 3779 C C   . TYR D 4 64  ? 283.886 372.250 434.063 1.00 87.38  ? 64  TYR B C   1 
ATOM 3780 O O   . TYR D 4 64  ? 283.547 371.235 434.666 1.00 87.38  ? 64  TYR B O   1 
ATOM 3781 C CB  . TYR D 4 64  ? 281.645 372.451 432.969 1.00 87.38  ? 64  TYR B CB  1 
ATOM 3782 C CG  . TYR D 4 64  ? 280.812 372.954 431.826 1.00 87.38  ? 64  TYR B CG  1 
ATOM 3783 C CD1 . TYR D 4 64  ? 280.445 374.284 431.750 1.00 87.38  ? 64  TYR B CD1 1 
ATOM 3784 C CD2 . TYR D 4 64  ? 280.381 372.098 430.832 1.00 87.38  ? 64  TYR B CD2 1 
ATOM 3785 C CE1 . TYR D 4 64  ? 279.684 374.747 430.711 1.00 87.38  ? 64  TYR B CE1 1 
ATOM 3786 C CE2 . TYR D 4 64  ? 279.618 372.550 429.793 1.00 87.38  ? 64  TYR B CE2 1 
ATOM 3787 C CZ  . TYR D 4 64  ? 279.274 373.875 429.737 1.00 87.38  ? 64  TYR B CZ  1 
ATOM 3788 O OH  . TYR D 4 64  ? 278.511 374.332 428.696 1.00 87.38  ? 64  TYR B OH  1 
ATOM 3789 N N   . THR D 4 65  ? 284.892 373.015 434.468 1.00 82.47  ? 65  THR B N   1 
ATOM 3790 C CA  . THR D 4 65  ? 285.714 372.659 435.615 1.00 82.47  ? 65  THR B CA  1 
ATOM 3791 C C   . THR D 4 65  ? 284.984 373.017 436.900 1.00 82.47  ? 65  THR B C   1 
ATOM 3792 O O   . THR D 4 65  ? 284.780 374.197 437.190 1.00 82.47  ? 65  THR B O   1 
ATOM 3793 C CB  . THR D 4 65  ? 287.057 373.375 435.566 1.00 82.47  ? 65  THR B CB  1 
ATOM 3794 O OG1 . THR D 4 65  ? 287.794 372.930 434.426 1.00 82.47  ? 65  THR B OG1 1 
ATOM 3795 C CG2 . THR D 4 65  ? 287.854 373.076 436.809 1.00 82.47  ? 65  THR B CG2 1 
ATOM 3796 N N   . LEU D 4 66  ? 284.595 372.005 437.665 1.00 84.35  ? 66  LEU B N   1 
ATOM 3797 C CA  . LEU D 4 66  ? 284.002 372.255 438.967 1.00 84.35  ? 66  LEU B CA  1 
ATOM 3798 C C   . LEU D 4 66  ? 285.118 372.726 439.886 1.00 84.35  ? 66  LEU B C   1 
ATOM 3799 O O   . LEU D 4 66  ? 286.298 372.459 439.655 1.00 84.35  ? 66  LEU B O   1 
ATOM 3800 C CB  . LEU D 4 66  ? 283.321 371.003 439.502 1.00 84.35  ? 66  LEU B CB  1 
ATOM 3801 C CG  . LEU D 4 66  ? 282.262 370.390 438.596 1.00 84.35  ? 66  LEU B CG  1 
ATOM 3802 C CD1 . LEU D 4 66  ? 281.608 369.224 439.284 1.00 84.35  ? 66  LEU B CD1 1 
ATOM 3803 C CD2 . LEU D 4 66  ? 281.234 371.421 438.235 1.00 84.35  ? 66  LEU B CD2 1 
ATOM 3804 N N   . GLU D 4 67  ? 284.737 373.440 440.937 1.00 91.47  ? 67  GLU B N   1 
ATOM 3805 C CA  . GLU D 4 67  ? 285.756 374.004 441.804 1.00 91.47  ? 67  GLU B CA  1 
ATOM 3806 C C   . GLU D 4 67  ? 286.257 372.925 442.752 1.00 91.47  ? 67  GLU B C   1 
ATOM 3807 O O   . GLU D 4 67  ? 285.613 371.896 442.951 1.00 91.47  ? 67  GLU B O   1 
ATOM 3808 C CB  . GLU D 4 67  ? 285.228 375.230 442.546 1.00 91.47  ? 67  GLU B CB  1 
ATOM 3809 C CG  . GLU D 4 67  ? 284.054 374.910 443.493 1.00 91.47  ? 67  GLU B CG  1 
ATOM 3810 C CD  . GLU D 4 67  ? 283.436 376.148 444.151 1.00 91.47  ? 67  GLU B CD  1 
ATOM 3811 O OE1 . GLU D 4 67  ? 284.086 377.211 444.167 1.00 91.47  ? 67  GLU B OE1 1 
ATOM 3812 O OE2 . GLU D 4 67  ? 282.298 376.056 444.660 1.00 91.47  ? 67  GLU B OE2 1 
ATOM 3813 N N   . SER D 4 68  ? 287.429 373.166 443.322 1.00 87.03  ? 68  SER B N   1 
ATOM 3814 C CA  . SER D 4 68  ? 288.213 372.120 443.959 1.00 87.03  ? 68  SER B CA  1 
ATOM 3815 C C   . SER D 4 68  ? 287.836 371.828 445.402 1.00 87.03  ? 68  SER B C   1 
ATOM 3816 O O   . SER D 4 68  ? 287.586 372.748 446.183 1.00 87.03  ? 68  SER B O   1 
ATOM 3817 C CB  . SER D 4 68  ? 289.665 372.574 443.897 1.00 87.03  ? 68  SER B CB  1 
ATOM 3818 O OG  . SER D 4 68  ? 289.987 373.309 445.060 1.00 87.03  ? 68  SER B OG  1 
ATOM 3819 N N   . VAL D 4 69  ? 287.823 370.551 445.754 1.00 80.97  ? 69  VAL B N   1 
ATOM 3820 C CA  . VAL D 4 69  ? 287.590 370.126 447.123 1.00 80.97  ? 69  VAL B CA  1 
ATOM 3821 C C   . VAL D 4 69  ? 288.926 369.827 447.786 1.00 80.97  ? 69  VAL B C   1 
ATOM 3822 O O   . VAL D 4 69  ? 289.930 369.569 447.124 1.00 80.97  ? 69  VAL B O   1 
ATOM 3823 C CB  . VAL D 4 69  ? 286.668 368.905 447.163 1.00 80.97  ? 69  VAL B CB  1 
ATOM 3824 C CG1 . VAL D 4 69  ? 285.318 369.280 446.632 1.00 80.97  ? 69  VAL B CG1 1 
ATOM 3825 C CG2 . VAL D 4 69  ? 287.256 367.803 446.332 1.00 80.97  ? 69  VAL B CG2 1 
ATOM 3826 N N   . GLN D 4 70  ? 288.943 369.856 449.112 1.00 86.63  ? 70  GLN B N   1 
ATOM 3827 C CA  . GLN D 4 70  ? 290.169 369.688 449.876 1.00 86.63  ? 70  GLN B CA  1 
ATOM 3828 C C   . GLN D 4 70  ? 290.172 368.338 450.565 1.00 86.63  ? 70  GLN B C   1 
ATOM 3829 O O   . GLN D 4 70  ? 289.187 367.963 451.202 1.00 86.63  ? 70  GLN B O   1 
ATOM 3830 C CB  . GLN D 4 70  ? 290.327 370.792 450.912 1.00 86.63  ? 70  GLN B CB  1 
ATOM 3831 C CG  . GLN D 4 70  ? 290.698 372.117 450.325 1.00 86.63  ? 70  GLN B CG  1 
ATOM 3832 C CD  . GLN D 4 70  ? 291.418 372.988 451.316 1.00 86.63  ? 70  GLN B CD  1 
ATOM 3833 O OE1 . GLN D 4 70  ? 291.242 372.846 452.523 1.00 86.63  ? 70  GLN B OE1 1 
ATOM 3834 N NE2 . GLN D 4 70  ? 292.242 373.897 450.814 1.00 86.63  ? 70  GLN B NE2 1 
ATOM 3835 N N   . TRP D 4 71  ? 291.282 367.627 450.454 1.00 80.59  ? 71  TRP B N   1 
ATOM 3836 C CA  . TRP D 4 71  ? 291.448 366.314 451.057 1.00 80.59  ? 71  TRP B CA  1 
ATOM 3837 C C   . TRP D 4 71  ? 292.313 366.479 452.297 1.00 80.59  ? 71  TRP B C   1 
ATOM 3838 O O   . TRP D 4 71  ? 293.516 366.719 452.191 1.00 80.59  ? 71  TRP B O   1 
ATOM 3839 C CB  . TRP D 4 71  ? 292.074 365.356 450.050 1.00 80.59  ? 71  TRP B CB  1 
ATOM 3840 C CG  . TRP D 4 71  ? 292.256 363.950 450.485 1.00 80.59  ? 71  TRP B CG  1 
ATOM 3841 C CD1 . TRP D 4 71  ? 291.763 363.357 451.600 1.00 80.59  ? 71  TRP B CD1 1 
ATOM 3842 C CD2 . TRP D 4 71  ? 292.982 362.941 449.785 1.00 80.59  ? 71  TRP B CD2 1 
ATOM 3843 N NE1 . TRP D 4 71  ? 292.150 362.044 451.648 1.00 80.59  ? 71  TRP B NE1 1 
ATOM 3844 C CE2 . TRP D 4 71  ? 292.898 361.767 450.538 1.00 80.59  ? 71  TRP B CE2 1 
ATOM 3845 C CE3 . TRP D 4 71  ? 293.698 362.923 448.591 1.00 80.59  ? 71  TRP B CE3 1 
ATOM 3846 C CZ2 . TRP D 4 71  ? 293.499 360.592 450.143 1.00 80.59  ? 71  TRP B CZ2 1 
ATOM 3847 C CZ3 . TRP D 4 71  ? 294.293 361.758 448.202 1.00 80.59  ? 71  TRP B CZ3 1 
ATOM 3848 C CH2 . TRP D 4 71  ? 294.192 360.608 448.973 1.00 80.59  ? 71  TRP B CH2 1 
ATOM 3849 N N   . MET D 4 72  ? 291.706 366.343 453.463 1.00 88.17  ? 72  MET B N   1 
ATOM 3850 C CA  . MET D 4 72  ? 292.406 366.463 454.726 1.00 88.17  ? 72  MET B CA  1 
ATOM 3851 C C   . MET D 4 72  ? 292.715 365.074 455.261 1.00 88.17  ? 72  MET B C   1 
ATOM 3852 O O   . MET D 4 72  ? 292.545 364.073 454.567 1.00 88.17  ? 72  MET B O   1 
ATOM 3853 C CB  . MET D 4 72  ? 291.579 367.286 455.704 1.00 88.17  ? 72  MET B CB  1 
ATOM 3854 C CG  . MET D 4 72  ? 291.287 368.668 455.197 1.00 88.17  ? 72  MET B CG  1 
ATOM 3855 S SD  . MET D 4 72  ? 291.046 369.871 456.505 1.00 88.17  ? 72  MET B SD  1 
ATOM 3856 C CE  . MET D 4 72  ? 291.766 371.317 455.734 1.00 88.17  ? 72  MET B CE  1 
ATOM 3857 N N   . LYS D 4 73  ? 293.192 365.008 456.504 1.00 85.36  ? 73  LYS B N   1 
ATOM 3858 C CA  . LYS D 4 73  ? 293.580 363.728 457.088 1.00 85.36  ? 73  LYS B CA  1 
ATOM 3859 C C   . LYS D 4 73  ? 292.372 362.844 457.345 1.00 85.36  ? 73  LYS B C   1 
ATOM 3860 O O   . LYS D 4 73  ? 292.293 361.723 456.834 1.00 85.36  ? 73  LYS B O   1 
ATOM 3861 C CB  . LYS D 4 73  ? 294.345 363.951 458.386 1.00 85.36  ? 73  LYS B CB  1 
ATOM 3862 C CG  . LYS D 4 73  ? 295.841 363.923 458.242 1.00 85.36  ? 73  LYS B CG  1 
ATOM 3863 C CD  . LYS D 4 73  ? 296.494 363.611 459.568 1.00 85.36  ? 73  LYS B CD  1 
ATOM 3864 C CE  . LYS D 4 73  ? 298.000 363.586 459.441 1.00 85.36  ? 73  LYS B CE  1 
ATOM 3865 N NZ  . LYS D 4 73  ? 298.652 363.115 460.691 1.00 85.36  ? 73  LYS B NZ  1 
ATOM 3866 N N   . ASN D 4 74  ? 291.422 363.325 458.133 1.00 90.99  ? 74  ASN B N   1 
ATOM 3867 C CA  . ASN D 4 74  ? 290.280 362.516 458.548 1.00 90.99  ? 74  ASN B CA  1 
ATOM 3868 C C   . ASN D 4 74  ? 289.093 362.721 457.612 1.00 90.99  ? 74  ASN B C   1 
ATOM 3869 O O   . ASN D 4 74  ? 287.964 362.913 458.040 1.00 90.99  ? 74  ASN B O   1 
ATOM 3870 C CB  . ASN D 4 74  ? 289.904 362.855 459.979 1.00 90.99  ? 74  ASN B CB  1 
ATOM 3871 C CG  . ASN D 4 74  ? 291.027 362.608 460.939 1.00 90.99  ? 74  ASN B CG  1 
ATOM 3872 O OD1 . ASN D 4 74  ? 291.686 361.574 460.877 1.00 90.99  ? 74  ASN B OD1 1 
ATOM 3873 N ND2 . ASN D 4 74  ? 291.268 363.559 461.830 1.00 90.99  ? 74  ASN B ND2 1 
ATOM 3874 N N   . SER D 4 75  ? 289.351 362.645 456.317 1.00 83.13  ? 75  SER B N   1 
ATOM 3875 C CA  . SER D 4 75  ? 288.315 362.884 455.329 1.00 83.13  ? 75  SER B CA  1 
ATOM 3876 C C   . SER D 4 75  ? 287.560 361.594 455.058 1.00 83.13  ? 75  SER B C   1 
ATOM 3877 O O   . SER D 4 75  ? 288.008 360.505 455.411 1.00 83.13  ? 75  SER B O   1 
ATOM 3878 C CB  . SER D 4 75  ? 288.915 363.433 454.040 1.00 83.13  ? 75  SER B CB  1 
ATOM 3879 O OG  . SER D 4 75  ? 287.893 363.736 453.116 1.00 83.13  ? 75  SER B OG  1 
ATOM 3880 N N   . ALA D 4 76  ? 286.407 361.723 454.441 1.00 78.33  ? 76  ALA B N   1 
ATOM 3881 C CA  . ALA D 4 76  ? 285.570 360.540 454.290 1.00 78.33  ? 76  ALA B CA  1 
ATOM 3882 C C   . ALA D 4 76  ? 285.213 360.215 452.852 1.00 78.33  ? 76  ALA B C   1 
ATOM 3883 O O   . ALA D 4 76  ? 285.213 359.043 452.487 1.00 78.33  ? 76  ALA B O   1 
ATOM 3884 C CB  . ALA D 4 76  ? 284.291 360.705 455.103 1.00 78.33  ? 76  ALA B CB  1 
ATOM 3885 N N   . GLY D 4 77  ? 284.893 361.203 452.040 1.00 76.37  ? 77  GLY B N   1 
ATOM 3886 C CA  . GLY D 4 77  ? 284.517 360.949 450.663 1.00 76.37  ? 77  GLY B CA  1 
ATOM 3887 C C   . GLY D 4 77  ? 283.580 362.017 450.148 1.00 76.37  ? 77  GLY B C   1 
ATOM 3888 O O   . GLY D 4 77  ? 283.035 362.816 450.897 1.00 76.37  ? 77  GLY B O   1 
ATOM 3889 N N   . TRP D 4 78  ? 283.400 362.020 448.830 1.00 75.60  ? 78  TRP B N   1 
ATOM 3890 C CA  . TRP D 4 78  ? 282.569 363.015 448.169 1.00 75.60  ? 78  TRP B CA  1 
ATOM 3891 C C   . TRP D 4 78  ? 281.735 362.346 447.089 1.00 75.60  ? 78  TRP B C   1 
ATOM 3892 O O   . TRP D 4 78  ? 282.095 361.287 446.576 1.00 75.60  ? 78  TRP B O   1 
ATOM 3893 C CB  . TRP D 4 78  ? 283.407 364.132 447.546 1.00 75.60  ? 78  TRP B CB  1 
ATOM 3894 C CG  . TRP D 4 78  ? 284.352 364.780 448.491 1.00 75.60  ? 78  TRP B CG  1 
ATOM 3895 C CD1 . TRP D 4 78  ? 284.118 365.877 449.248 1.00 75.60  ? 78  TRP B CD1 1 
ATOM 3896 C CD2 . TRP D 4 78  ? 285.686 364.369 448.781 1.00 75.60  ? 78  TRP B CD2 1 
ATOM 3897 N NE1 . TRP D 4 78  ? 285.220 366.180 449.997 1.00 75.60  ? 78  TRP B NE1 1 
ATOM 3898 C CE2 . TRP D 4 78  ? 286.199 365.264 449.726 1.00 75.60  ? 78  TRP B CE2 1 
ATOM 3899 C CE3 . TRP D 4 78  ? 286.497 363.330 448.333 1.00 75.60  ? 78  TRP B CE3 1 
ATOM 3900 C CZ2 . TRP D 4 78  ? 287.479 365.152 450.231 1.00 75.60  ? 78  TRP B CZ2 1 
ATOM 3901 C CZ3 . TRP D 4 78  ? 287.766 363.224 448.833 1.00 75.60  ? 78  TRP B CZ3 1 
ATOM 3902 C CH2 . TRP D 4 78  ? 288.246 364.127 449.770 1.00 75.60  ? 78  TRP B CH2 1 
ATOM 3903 N N   . TRP D 4 79  ? 280.615 362.973 446.736 1.00 80.34  ? 79  TRP B N   1 
ATOM 3904 C CA  . TRP D 4 79  ? 279.823 362.480 445.620 1.00 80.34  ? 79  TRP B CA  1 
ATOM 3905 C C   . TRP D 4 79  ? 279.145 363.639 444.910 1.00 80.34  ? 79  TRP B C   1 
ATOM 3906 O O   . TRP D 4 79  ? 278.717 364.605 445.539 1.00 80.34  ? 79  TRP B O   1 
ATOM 3907 C CB  . TRP D 4 79  ? 278.789 361.431 446.058 1.00 80.34  ? 79  TRP B CB  1 
ATOM 3908 C CG  . TRP D 4 79  ? 277.448 361.917 446.553 1.00 80.34  ? 79  TRP B CG  1 
ATOM 3909 C CD1 . TRP D 4 79  ? 276.373 362.272 445.800 1.00 80.34  ? 79  TRP B CD1 1 
ATOM 3910 C CD2 . TRP D 4 79  ? 277.021 362.007 447.911 1.00 80.34  ? 79  TRP B CD2 1 
ATOM 3911 N NE1 . TRP D 4 79  ? 275.327 362.628 446.599 1.00 80.34  ? 79  TRP B NE1 1 
ATOM 3912 C CE2 . TRP D 4 79  ? 275.698 362.465 447.903 1.00 80.34  ? 79  TRP B CE2 1 
ATOM 3913 C CE3 . TRP D 4 79  ? 277.636 361.762 449.134 1.00 80.34  ? 79  TRP B CE3 1 
ATOM 3914 C CZ2 . TRP D 4 79  ? 274.984 362.685 449.064 1.00 80.34  ? 79  TRP B CZ2 1 
ATOM 3915 C CZ3 . TRP D 4 79  ? 276.923 361.983 450.285 1.00 80.34  ? 79  TRP B CZ3 1 
ATOM 3916 C CH2 . TRP D 4 79  ? 275.612 362.437 450.244 1.00 80.34  ? 79  TRP B CH2 1 
ATOM 3917 N N   . TRP D 4 80  ? 279.034 363.517 443.594 1.00 78.22  ? 80  TRP B N   1 
ATOM 3918 C CA  . TRP D 4 80  ? 278.313 364.462 442.758 1.00 78.22  ? 80  TRP B CA  1 
ATOM 3919 C C   . TRP D 4 80  ? 277.250 363.717 441.964 1.00 78.22  ? 80  TRP B C   1 
ATOM 3920 O O   . TRP D 4 80  ? 277.498 362.623 441.457 1.00 78.22  ? 80  TRP B O   1 
ATOM 3921 C CB  . TRP D 4 80  ? 279.242 365.165 441.772 1.00 78.22  ? 80  TRP B CB  1 
ATOM 3922 C CG  . TRP D 4 80  ? 280.259 366.076 442.354 1.00 78.22  ? 80  TRP B CG  1 
ATOM 3923 C CD1 . TRP D 4 80  ? 280.122 367.403 442.594 1.00 78.22  ? 80  TRP B CD1 1 
ATOM 3924 C CD2 . TRP D 4 80  ? 281.594 365.739 442.726 1.00 78.22  ? 80  TRP B CD2 1 
ATOM 3925 N NE1 . TRP D 4 80  ? 281.280 367.914 443.111 1.00 78.22  ? 80  TRP B NE1 1 
ATOM 3926 C CE2 . TRP D 4 80  ? 282.201 366.909 443.202 1.00 78.22  ? 80  TRP B CE2 1 
ATOM 3927 C CE3 . TRP D 4 80  ? 282.330 364.559 442.715 1.00 78.22  ? 80  TRP B CE3 1 
ATOM 3928 C CZ2 . TRP D 4 80  ? 283.507 366.932 443.659 1.00 78.22  ? 80  TRP B CZ2 1 
ATOM 3929 C CZ3 . TRP D 4 80  ? 283.625 364.584 443.172 1.00 78.22  ? 80  TRP B CZ3 1 
ATOM 3930 C CH2 . TRP D 4 80  ? 284.199 365.758 443.640 1.00 78.22  ? 80  TRP B CH2 1 
ATOM 3931 N N   . LYS D 4 81  ? 276.068 364.308 441.847 1.00 81.99  ? 81  LYS B N   1 
ATOM 3932 C CA  . LYS D 4 81  ? 275.033 363.800 440.956 1.00 81.99  ? 81  LYS B CA  1 
ATOM 3933 C C   . LYS D 4 81  ? 275.215 364.463 439.605 1.00 81.99  ? 81  LYS B C   1 
ATOM 3934 O O   . LYS D 4 81  ? 275.328 365.688 439.531 1.00 81.99  ? 81  LYS B O   1 
ATOM 3935 C CB  . LYS D 4 81  ? 273.640 364.090 441.503 1.00 81.99  ? 81  LYS B CB  1 
ATOM 3936 C CG  . LYS D 4 81  ? 273.340 363.405 442.806 1.00 81.99  ? 81  LYS B CG  1 
ATOM 3937 C CD  . LYS D 4 81  ? 273.056 361.948 442.593 1.00 81.99  ? 81  LYS B CD  1 
ATOM 3938 C CE  . LYS D 4 81  ? 272.546 361.319 443.859 1.00 81.99  ? 81  LYS B CE  1 
ATOM 3939 N NZ  . LYS D 4 81  ? 272.057 359.947 443.612 1.00 81.99  ? 81  LYS B NZ  1 
ATOM 3940 N N   . LEU D 4 82  ? 275.240 363.669 438.541 1.00 85.34  ? 82  LEU B N   1 
ATOM 3941 C CA  . LEU D 4 82  ? 275.920 364.193 437.365 1.00 85.34  ? 82  LEU B CA  1 
ATOM 3942 C C   . LEU D 4 82  ? 275.131 365.162 436.488 1.00 85.34  ? 82  LEU B C   1 
ATOM 3943 O O   . LEU D 4 82  ? 275.684 366.220 436.169 1.00 85.34  ? 82  LEU B O   1 
ATOM 3944 C CB  . LEU D 4 82  ? 276.472 363.061 436.506 1.00 85.34  ? 82  LEU B CB  1 
ATOM 3945 C CG  . LEU D 4 82  ? 277.654 363.551 435.673 1.00 85.34  ? 82  LEU B CG  1 
ATOM 3946 C CD1 . LEU D 4 82  ? 278.651 364.335 436.510 1.00 85.34  ? 82  LEU B CD1 1 
ATOM 3947 C CD2 . LEU D 4 82  ? 278.340 362.386 435.029 1.00 85.34  ? 82  LEU B CD2 1 
ATOM 3948 N N   . PRO D 4 83  ? 273.868 364.914 436.058 1.00 86.02  ? 83  PRO B N   1 
ATOM 3949 C CA  . PRO D 4 83  ? 273.182 365.995 435.341 1.00 86.02  ? 83  PRO B CA  1 
ATOM 3950 C C   . PRO D 4 83  ? 272.461 366.942 436.283 1.00 86.02  ? 83  PRO B C   1 
ATOM 3951 O O   . PRO D 4 83  ? 271.327 367.343 436.018 1.00 86.02  ? 83  PRO B O   1 
ATOM 3952 C CB  . PRO D 4 83  ? 272.204 365.240 434.447 1.00 86.02  ? 83  PRO B CB  1 
ATOM 3953 C CG  . PRO D 4 83  ? 271.805 364.113 435.276 1.00 86.02  ? 83  PRO B CG  1 
ATOM 3954 C CD  . PRO D 4 83  ? 272.992 363.731 436.134 1.00 86.02  ? 83  PRO B CD  1 
ATOM 3955 N N   . ASP D 4 84  ? 273.109 367.304 437.385 1.00 95.31  ? 84  ASP B N   1 
ATOM 3956 C CA  . ASP D 4 84  ? 272.564 368.225 438.365 1.00 95.31  ? 84  ASP B CA  1 
ATOM 3957 C C   . ASP D 4 84  ? 273.700 369.168 438.731 1.00 95.31  ? 84  ASP B C   1 
ATOM 3958 O O   . ASP D 4 84  ? 273.482 370.342 439.038 1.00 95.31  ? 84  ASP B O   1 
ATOM 3959 C CB  . ASP D 4 84  ? 272.031 367.434 439.564 1.00 95.31  ? 84  ASP B CB  1 
ATOM 3960 C CG  . ASP D 4 84  ? 271.224 368.270 440.556 1.00 95.31  ? 84  ASP B CG  1 
ATOM 3961 O OD1 . ASP D 4 84  ? 271.500 369.459 440.798 1.00 95.31  ? 84  ASP B OD1 1 
ATOM 3962 O OD2 . ASP D 4 84  ? 270.268 367.703 441.122 1.00 95.31  ? 84  ASP B OD2 1 
ATOM 3963 N N   . ALA D 4 85  ? 274.930 368.665 438.652 1.00 96.02  ? 85  ALA B N   1 
ATOM 3964 C CA  . ALA D 4 85  ? 276.087 369.484 438.987 1.00 96.02  ? 85  ALA B CA  1 
ATOM 3965 C C   . ALA D 4 85  ? 276.364 370.534 437.926 1.00 96.02  ? 85  ALA B C   1 
ATOM 3966 O O   . ALA D 4 85  ? 277.002 371.548 438.218 1.00 96.02  ? 85  ALA B O   1 
ATOM 3967 C CB  . ALA D 4 85  ? 277.315 368.604 439.181 1.00 96.02  ? 85  ALA B CB  1 
ATOM 3968 N N   . LEU D 4 86  ? 275.894 370.314 436.700 1.00 94.96  ? 86  LEU B N   1 
ATOM 3969 C CA  . LEU D 4 86  ? 276.021 371.284 435.622 1.00 94.96  ? 86  LEU B CA  1 
ATOM 3970 C C   . LEU D 4 86  ? 274.727 372.049 435.380 1.00 94.96  ? 86  LEU B C   1 
ATOM 3971 O O   . LEU D 4 86  ? 274.490 372.523 434.268 1.00 94.96  ? 86  LEU B O   1 
ATOM 3972 C CB  . LEU D 4 86  ? 276.459 370.585 434.341 1.00 94.96  ? 86  LEU B CB  1 
ATOM 3973 C CG  . LEU D 4 86  ? 277.579 369.576 434.525 1.00 94.96  ? 86  LEU B CG  1 
ATOM 3974 C CD1 . LEU D 4 86  ? 277.752 368.769 433.271 1.00 94.96  ? 86  LEU B CD1 1 
ATOM 3975 C CD2 . LEU D 4 86  ? 278.844 370.307 434.850 1.00 94.96  ? 86  LEU B CD2 1 
ATOM 3976 N N   . SER D 4 87  ? 273.881 372.179 436.398 1.00 100.93 ? 87  SER B N   1 
ATOM 3977 C CA  . SER D 4 87  ? 272.584 372.806 436.191 1.00 100.93 ? 87  SER B CA  1 
ATOM 3978 C C   . SER D 4 87  ? 272.659 374.320 436.150 1.00 100.93 ? 87  SER B C   1 
ATOM 3979 O O   . SER D 4 87  ? 271.716 374.955 435.673 1.00 100.93 ? 87  SER B O   1 
ATOM 3980 C CB  . SER D 4 87  ? 271.609 372.388 437.283 1.00 100.93 ? 87  SER B CB  1 
ATOM 3981 O OG  . SER D 4 87  ? 271.956 372.994 438.512 1.00 100.93 ? 87  SER B OG  1 
ATOM 3982 N N   . GLN D 4 88  ? 273.740 374.915 436.644 1.00 102.54 ? 88  GLN B N   1 
ATOM 3983 C CA  . GLN D 4 88  ? 273.936 376.354 436.557 1.00 102.54 ? 88  GLN B CA  1 
ATOM 3984 C C   . GLN D 4 88  ? 275.134 376.726 435.704 1.00 102.54 ? 88  GLN B C   1 
ATOM 3985 O O   . GLN D 4 88  ? 275.501 377.901 435.644 1.00 102.54 ? 88  GLN B O   1 
ATOM 3986 C CB  . GLN D 4 88  ? 274.095 376.961 437.949 1.00 102.54 ? 88  GLN B CB  1 
ATOM 3987 C CG  . GLN D 4 88  ? 272.793 377.264 438.641 1.00 102.54 ? 88  GLN B CG  1 
ATOM 3988 C CD  . GLN D 4 88  ? 272.198 376.048 439.291 1.00 102.54 ? 88  GLN B CD  1 
ATOM 3989 O OE1 . GLN D 4 88  ? 271.091 375.631 438.958 1.00 102.54 ? 88  GLN B OE1 1 
ATOM 3990 N NE2 . GLN D 4 88  ? 272.929 375.464 440.227 1.00 102.54 ? 88  GLN B NE2 1 
ATOM 3991 N N   . MET D 4 89  ? 275.746 375.758 435.030 1.00 100.60 ? 89  MET B N   1 
ATOM 3992 C CA  . MET D 4 89  ? 277.023 375.988 434.366 1.00 100.60 ? 89  MET B CA  1 
ATOM 3993 C C   . MET D 4 89  ? 276.774 376.489 432.950 1.00 100.60 ? 89  MET B C   1 
ATOM 3994 O O   . MET D 4 89  ? 276.862 375.753 431.968 1.00 100.60 ? 89  MET B O   1 
ATOM 3995 C CB  . MET D 4 89  ? 277.858 374.717 434.377 1.00 100.60 ? 89  MET B CB  1 
ATOM 3996 C CG  . MET D 4 89  ? 278.417 374.374 435.737 1.00 100.60 ? 89  MET B CG  1 
ATOM 3997 S SD  . MET D 4 89  ? 279.772 375.453 436.201 1.00 100.60 ? 89  MET B SD  1 
ATOM 3998 C CE  . MET D 4 89  ? 279.991 374.972 437.905 1.00 100.60 ? 89  MET B CE  1 
ATOM 3999 N N   . GLY D 4 90  ? 276.462 377.776 432.852 1.00 101.38 ? 90  GLY B N   1 
ATOM 4000 C CA  . GLY D 4 90  ? 276.463 378.456 431.574 1.00 101.38 ? 90  GLY B CA  1 
ATOM 4001 C C   . GLY D 4 90  ? 275.344 378.067 430.636 1.00 101.38 ? 90  GLY B C   1 
ATOM 4002 O O   . GLY D 4 90  ? 274.175 378.057 431.027 1.00 101.38 ? 90  GLY B O   1 
ATOM 4003 N N   . LEU D 4 91  ? 275.690 377.741 429.393 1.00 101.94 ? 91  LEU B N   1 
ATOM 4004 C CA  . LEU D 4 91  ? 274.677 377.417 428.400 1.00 101.94 ? 91  LEU B CA  1 
ATOM 4005 C C   . LEU D 4 91  ? 274.092 376.031 428.603 1.00 101.94 ? 91  LEU B C   1 
ATOM 4006 O O   . LEU D 4 91  ? 272.949 375.794 428.202 1.00 101.94 ? 91  LEU B O   1 
ATOM 4007 C CB  . LEU D 4 91  ? 275.262 377.557 426.992 1.00 101.94 ? 91  LEU B CB  1 
ATOM 4008 C CG  . LEU D 4 91  ? 274.323 377.542 425.783 1.00 101.94 ? 91  LEU B CG  1 
ATOM 4009 C CD1 . LEU D 4 91  ? 274.814 378.529 424.758 1.00 101.94 ? 91  LEU B CD1 1 
ATOM 4010 C CD2 . LEU D 4 91  ? 274.241 376.168 425.147 1.00 101.94 ? 91  LEU B CD2 1 
ATOM 4011 N N   . PHE D 4 92  ? 274.833 375.114 429.221 1.00 98.39  ? 92  PHE B N   1 
ATOM 4012 C CA  . PHE D 4 92  ? 274.260 373.812 429.528 1.00 98.39  ? 92  PHE B CA  1 
ATOM 4013 C C   . PHE D 4 92  ? 273.191 373.914 430.603 1.00 98.39  ? 92  PHE B C   1 
ATOM 4014 O O   . PHE D 4 92  ? 272.302 373.064 430.672 1.00 98.39  ? 92  PHE B O   1 
ATOM 4015 C CB  . PHE D 4 92  ? 275.349 372.845 429.964 1.00 98.39  ? 92  PHE B CB  1 
ATOM 4016 C CG  . PHE D 4 92  ? 274.910 371.423 429.988 1.00 98.39  ? 92  PHE B CG  1 
ATOM 4017 C CD1 . PHE D 4 92  ? 274.846 370.692 428.825 1.00 98.39  ? 92  PHE B CD1 1 
ATOM 4018 C CD2 . PHE D 4 92  ? 274.560 370.816 431.175 1.00 98.39  ? 92  PHE B CD2 1 
ATOM 4019 C CE1 . PHE D 4 92  ? 274.444 369.381 428.845 1.00 98.39  ? 92  PHE B CE1 1 
ATOM 4020 C CE2 . PHE D 4 92  ? 274.154 369.506 431.199 1.00 98.39  ? 92  PHE B CE2 1 
ATOM 4021 C CZ  . PHE D 4 92  ? 274.096 368.789 430.034 1.00 98.39  ? 92  PHE B CZ  1 
ATOM 4022 N N   . GLY D 4 93  ? 273.255 374.942 431.447 1.00 100.30 ? 93  GLY B N   1 
ATOM 4023 C CA  . GLY D 4 93  ? 272.184 375.177 432.390 1.00 100.30 ? 93  GLY B CA  1 
ATOM 4024 C C   . GLY D 4 93  ? 270.979 375.848 431.778 1.00 100.30 ? 93  GLY B C   1 
ATOM 4025 O O   . GLY D 4 93  ? 269.910 375.855 432.392 1.00 100.30 ? 93  GLY B O   1 
ATOM 4026 N N   . GLN D 4 94  ? 271.129 376.423 430.587 1.00 102.88 ? 94  GLN B N   1 
ATOM 4027 C CA  . GLN D 4 94  ? 269.989 377.015 429.905 1.00 102.88 ? 94  GLN B CA  1 
ATOM 4028 C C   . GLN D 4 94  ? 269.249 375.996 429.061 1.00 102.88 ? 94  GLN B C   1 
ATOM 4029 O O   . GLN D 4 94  ? 268.021 376.057 428.957 1.00 102.88 ? 94  GLN B O   1 
ATOM 4030 C CB  . GLN D 4 94  ? 270.439 378.183 429.024 1.00 102.88 ? 94  GLN B CB  1 
ATOM 4031 C CG  . GLN D 4 94  ? 271.242 379.294 429.713 1.00 102.88 ? 94  GLN B CG  1 
ATOM 4032 C CD  . GLN D 4 94  ? 270.634 379.846 431.000 1.00 102.88 ? 94  GLN B CD  1 
ATOM 4033 O OE1 . GLN D 4 94  ? 269.413 379.892 431.178 1.00 102.88 ? 94  GLN B OE1 1 
ATOM 4034 N NE2 . GLN D 4 94  ? 271.500 380.272 431.912 1.00 102.88 ? 94  GLN B NE2 1 
ATOM 4035 N N   . ASN D 4 95  ? 269.965 375.054 428.456 1.00 102.59 ? 95  ASN B N   1 
ATOM 4036 C CA  . ASN D 4 95  ? 269.310 374.031 427.660 1.00 102.59 ? 95  ASN B CA  1 
ATOM 4037 C C   . ASN D 4 95  ? 268.643 372.966 428.510 1.00 102.59 ? 95  ASN B C   1 
ATOM 4038 O O   . ASN D 4 95  ? 267.867 372.169 427.978 1.00 102.59 ? 95  ASN B O   1 
ATOM 4039 C CB  . ASN D 4 95  ? 270.310 373.383 426.713 1.00 102.59 ? 95  ASN B CB  1 
ATOM 4040 C CG  . ASN D 4 95  ? 270.640 374.269 425.551 1.00 102.59 ? 95  ASN B CG  1 
ATOM 4041 O OD1 . ASN D 4 95  ? 270.285 375.443 425.541 1.00 102.59 ? 95  ASN B OD1 1 
ATOM 4042 N ND2 . ASN D 4 95  ? 271.322 373.722 424.559 1.00 102.59 ? 95  ASN B ND2 1 
ATOM 4043 N N   . MET D 4 96  ? 268.925 372.923 429.807 1.00 105.13 ? 96  MET B N   1 
ATOM 4044 C CA  . MET D 4 96  ? 268.185 372.017 430.669 1.00 105.13 ? 96  MET B CA  1 
ATOM 4045 C C   . MET D 4 96  ? 266.802 372.555 430.993 1.00 105.13 ? 96  MET B C   1 
ATOM 4046 O O   . MET D 4 96  ? 265.871 371.771 431.186 1.00 105.13 ? 96  MET B O   1 
ATOM 4047 C CB  . MET D 4 96  ? 268.962 371.751 431.953 1.00 105.13 ? 96  MET B CB  1 
ATOM 4048 C CG  . MET D 4 96  ? 269.964 370.627 431.830 1.00 105.13 ? 96  MET B CG  1 
ATOM 4049 S SD  . MET D 4 96  ? 270.851 370.317 433.362 1.00 105.13 ? 96  MET B SD  1 
ATOM 4050 C CE  . MET D 4 96  ? 269.499 370.296 434.529 1.00 105.13 ? 96  MET B CE  1 
ATOM 4051 N N   . GLN D 4 97  ? 266.640 373.875 431.048 1.00 106.87 ? 97  GLN B N   1 
ATOM 4052 C CA  . GLN D 4 97  ? 265.342 374.456 431.362 1.00 106.87 ? 97  GLN B CA  1 
ATOM 4053 C C   . GLN D 4 97  ? 264.486 374.704 430.135 1.00 106.87 ? 97  GLN B C   1 
ATOM 4054 O O   . GLN D 4 97  ? 263.256 374.691 430.237 1.00 106.87 ? 97  GLN B O   1 
ATOM 4055 C CB  . GLN D 4 97  ? 265.514 375.776 432.108 1.00 106.87 ? 97  GLN B CB  1 
ATOM 4056 C CG  . GLN D 4 97  ? 266.172 375.634 433.448 1.00 106.87 ? 97  GLN B CG  1 
ATOM 4057 C CD  . GLN D 4 97  ? 266.421 376.967 434.098 1.00 106.87 ? 97  GLN B CD  1 
ATOM 4058 O OE1 . GLN D 4 97  ? 265.850 377.978 433.693 1.00 106.87 ? 97  GLN B OE1 1 
ATOM 4059 N NE2 . GLN D 4 97  ? 267.280 376.983 435.107 1.00 106.87 ? 97  GLN B NE2 1 
ATOM 4060 N N   . TYR D 4 98  ? 265.098 374.940 428.982 1.00 109.95 ? 98  TYR B N   1 
ATOM 4061 C CA  . TYR D 4 98  ? 264.312 375.251 427.797 1.00 109.95 ? 98  TYR B CA  1 
ATOM 4062 C C   . TYR D 4 98  ? 263.792 373.996 427.118 1.00 109.95 ? 98  TYR B C   1 
ATOM 4063 O O   . TYR D 4 98  ? 262.652 373.981 426.647 1.00 109.95 ? 98  TYR B O   1 
ATOM 4064 C CB  . TYR D 4 98  ? 265.148 376.066 426.815 1.00 109.95 ? 98  TYR B CB  1 
ATOM 4065 C CG  . TYR D 4 98  ? 265.092 377.558 427.033 1.00 109.95 ? 98  TYR B CG  1 
ATOM 4066 C CD1 . TYR D 4 98  ? 265.151 378.099 428.310 1.00 109.95 ? 98  TYR B CD1 1 
ATOM 4067 C CD2 . TYR D 4 98  ? 265.003 378.428 425.957 1.00 109.95 ? 98  TYR B CD2 1 
ATOM 4068 C CE1 . TYR D 4 98  ? 265.108 379.463 428.512 1.00 109.95 ? 98  TYR B CE1 1 
ATOM 4069 C CE2 . TYR D 4 98  ? 264.959 379.796 426.146 1.00 109.95 ? 98  TYR B CE2 1 
ATOM 4070 C CZ  . TYR D 4 98  ? 265.013 380.306 427.425 1.00 109.95 ? 98  TYR B CZ  1 
ATOM 4071 O OH  . TYR D 4 98  ? 264.970 381.666 427.617 1.00 109.95 ? 98  TYR B OH  1 
ATOM 4072 N N   . HIS D 4 99  ? 264.596 372.944 427.065 1.00 104.45 ? 99  HIS B N   1 
ATOM 4073 C CA  . HIS D 4 99  ? 264.221 371.707 426.406 1.00 104.45 ? 99  HIS B CA  1 
ATOM 4074 C C   . HIS D 4 99  ? 263.785 370.675 427.434 1.00 104.45 ? 99  HIS B C   1 
ATOM 4075 O O   . HIS D 4 99  ? 264.389 370.535 428.498 1.00 104.45 ? 99  HIS B O   1 
ATOM 4076 C CB  . HIS D 4 99  ? 265.380 371.162 425.582 1.00 104.45 ? 99  HIS B CB  1 
ATOM 4077 C CG  . HIS D 4 99  ? 265.706 371.993 424.385 1.00 104.45 ? 99  HIS B CG  1 
ATOM 4078 N ND1 . HIS D 4 99  ? 266.177 373.283 424.481 1.00 104.45 ? 99  HIS B ND1 1 
ATOM 4079 C CD2 . HIS D 4 99  ? 265.630 371.718 423.064 1.00 104.45 ? 99  HIS B CD2 1 
ATOM 4080 C CE1 . HIS D 4 99  ? 266.380 373.766 423.269 1.00 104.45 ? 99  HIS B CE1 1 
ATOM 4081 N NE2 . HIS D 4 99  ? 266.057 372.836 422.391 1.00 104.45 ? 99  HIS B NE2 1 
ATOM 4082 N N   . TYR D 4 100 ? 262.731 369.939 427.095 1.00 108.75 ? 100 TYR B N   1 
ATOM 4083 C CA  . TYR D 4 100 ? 262.116 369.005 428.027 1.00 108.75 ? 100 TYR B CA  1 
ATOM 4084 C C   . TYR D 4 100 ? 262.929 367.725 428.184 1.00 108.75 ? 100 TYR B C   1 
ATOM 4085 O O   . TYR D 4 100 ? 263.218 367.308 429.308 1.00 108.75 ? 100 TYR B O   1 
ATOM 4086 C CB  . TYR D 4 100 ? 260.695 368.680 427.564 1.00 108.75 ? 100 TYR B CB  1 
ATOM 4087 C CG  . TYR D 4 100 ? 259.776 368.208 428.661 1.00 108.75 ? 100 TYR B CG  1 
ATOM 4088 C CD1 . TYR D 4 100 ? 259.583 368.964 429.806 1.00 108.75 ? 100 TYR B CD1 1 
ATOM 4089 C CD2 . TYR D 4 100 ? 259.084 367.012 428.541 1.00 108.75 ? 100 TYR B CD2 1 
ATOM 4090 C CE1 . TYR D 4 100 ? 258.732 368.535 430.809 1.00 108.75 ? 100 TYR B CE1 1 
ATOM 4091 C CE2 . TYR D 4 100 ? 258.234 366.572 429.538 1.00 108.75 ? 100 TYR B CE2 1 
ATOM 4092 C CZ  . TYR D 4 100 ? 258.061 367.337 430.668 1.00 108.75 ? 100 TYR B CZ  1 
ATOM 4093 O OH  . TYR D 4 100 ? 257.214 366.898 431.659 1.00 108.75 ? 100 TYR B OH  1 
ATOM 4094 N N   . LEU D 4 101 ? 263.309 367.099 427.082 1.00 100.71 ? 101 LEU B N   1 
ATOM 4095 C CA  . LEU D 4 101 ? 264.012 365.828 427.098 1.00 100.71 ? 101 LEU B CA  1 
ATOM 4096 C C   . LEU D 4 101 ? 265.475 366.044 426.742 1.00 100.71 ? 101 LEU B C   1 
ATOM 4097 O O   . LEU D 4 101 ? 265.937 367.174 426.590 1.00 100.71 ? 101 LEU B O   1 
ATOM 4098 C CB  . LEU D 4 101 ? 263.347 364.849 426.136 1.00 100.71 ? 101 LEU B CB  1 
ATOM 4099 C CG  . LEU D 4 101 ? 261.827 364.780 426.233 1.00 100.71 ? 101 LEU B CG  1 
ATOM 4100 C CD1 . LEU D 4 101 ? 261.280 363.842 425.189 1.00 100.71 ? 101 LEU B CD1 1 
ATOM 4101 C CD2 . LEU D 4 101 ? 261.415 364.321 427.606 1.00 100.71 ? 101 LEU B CD2 1 
ATOM 4102 N N   . GLY D 4 102 ? 266.208 364.951 426.615 1.00 95.66  ? 102 GLY B N   1 
ATOM 4103 C CA  . GLY D 4 102 ? 267.601 365.026 426.223 1.00 95.66  ? 102 GLY B CA  1 
ATOM 4104 C C   . GLY D 4 102 ? 268.385 363.831 426.703 1.00 95.66  ? 102 GLY B C   1 
ATOM 4105 O O   . GLY D 4 102 ? 267.997 363.123 427.628 1.00 95.66  ? 102 GLY B O   1 
ATOM 4106 N N   . ARG D 4 103 ? 269.521 363.606 426.049 1.00 92.47  ? 103 ARG B N   1 
ATOM 4107 C CA  . ARG D 4 103 ? 270.417 362.515 426.393 1.00 92.47  ? 103 ARG B CA  1 
ATOM 4108 C C   . ARG D 4 103 ? 271.846 362.917 426.075 1.00 92.47  ? 103 ARG B C   1 
ATOM 4109 O O   . ARG D 4 103 ? 272.122 363.446 424.998 1.00 92.47  ? 103 ARG B O   1 
ATOM 4110 C CB  . ARG D 4 103 ? 270.064 361.239 425.636 1.00 92.47  ? 103 ARG B CB  1 
ATOM 4111 C CG  . ARG D 4 103 ? 269.717 361.454 424.185 1.00 92.47  ? 103 ARG B CG  1 
ATOM 4112 C CD  . ARG D 4 103 ? 269.705 360.148 423.446 1.00 92.47  ? 103 ARG B CD  1 
ATOM 4113 N NE  . ARG D 4 103 ? 271.041 359.591 423.329 1.00 92.47  ? 103 ARG B NE  1 
ATOM 4114 C CZ  . ARG D 4 103 ? 271.291 358.295 423.229 1.00 92.47  ? 103 ARG B CZ  1 
ATOM 4115 N NH1 . ARG D 4 103 ? 270.294 357.428 423.243 1.00 92.47  ? 103 ARG B NH1 1 
ATOM 4116 N NH2 . ARG D 4 103 ? 272.536 357.864 423.123 1.00 92.47  ? 103 ARG B NH2 1 
ATOM 4117 N N   . THR D 4 104 ? 272.751 362.692 427.025 1.00 92.52  ? 104 THR B N   1 
ATOM 4118 C CA  . THR D 4 104 ? 274.149 363.065 426.862 1.00 92.52  ? 104 THR B CA  1 
ATOM 4119 C C   . THR D 4 104 ? 275.051 361.896 427.225 1.00 92.52  ? 104 THR B C   1 
ATOM 4120 O O   . THR D 4 104 ? 274.614 360.898 427.795 1.00 92.52  ? 104 THR B O   1 
ATOM 4121 C CB  . THR D 4 104 ? 274.560 364.255 427.744 1.00 92.52  ? 104 THR B CB  1 
ATOM 4122 O OG1 . THR D 4 104 ? 274.730 363.800 429.088 1.00 92.52  ? 104 THR B OG1 1 
ATOM 4123 C CG2 . THR D 4 104 ? 273.547 365.389 427.723 1.00 92.52  ? 104 THR B CG2 1 
ATOM 4124 N N   . GLY D 4 105 ? 276.328 362.042 426.876 1.00 90.70  ? 105 GLY B N   1 
ATOM 4125 C CA  . GLY D 4 105 ? 277.399 361.260 427.449 1.00 90.70  ? 105 GLY B CA  1 
ATOM 4126 C C   . GLY D 4 105 ? 278.385 362.186 428.139 1.00 90.70  ? 105 GLY B C   1 
ATOM 4127 O O   . GLY D 4 105 ? 278.304 363.408 428.018 1.00 90.70  ? 105 GLY B O   1 
ATOM 4128 N N   . TYR D 4 106 ? 279.328 361.587 428.859 1.00 85.99  ? 106 TYR B N   1 
ATOM 4129 C CA  . TYR D 4 106 ? 280.218 362.384 429.687 1.00 85.99  ? 106 TYR B CA  1 
ATOM 4130 C C   . TYR D 4 106 ? 281.660 361.945 429.511 1.00 85.99  ? 106 TYR B C   1 
ATOM 4131 O O   . TYR D 4 106 ? 281.945 360.870 428.989 1.00 85.99  ? 106 TYR B O   1 
ATOM 4132 C CB  . TYR D 4 106 ? 279.831 362.298 431.155 1.00 85.99  ? 106 TYR B CB  1 
ATOM 4133 C CG  . TYR D 4 106 ? 278.497 362.912 431.436 1.00 85.99  ? 106 TYR B CG  1 
ATOM 4134 C CD1 . TYR D 4 106 ? 278.367 364.277 431.605 1.00 85.99  ? 106 TYR B CD1 1 
ATOM 4135 C CD2 . TYR D 4 106 ? 277.363 362.130 431.515 1.00 85.99  ? 106 TYR B CD2 1 
ATOM 4136 C CE1 . TYR D 4 106 ? 277.148 364.843 431.856 1.00 85.99  ? 106 TYR B CE1 1 
ATOM 4137 C CE2 . TYR D 4 106 ? 276.140 362.683 431.767 1.00 85.99  ? 106 TYR B CE2 1 
ATOM 4138 C CZ  . TYR D 4 106 ? 276.038 364.041 431.937 1.00 85.99  ? 106 TYR B CZ  1 
ATOM 4139 O OH  . TYR D 4 106 ? 274.808 364.598 432.187 1.00 85.99  ? 106 TYR B OH  1 
ATOM 4140 N N   . THR D 4 107 ? 282.567 362.807 429.961 1.00 82.93  ? 107 THR B N   1 
ATOM 4141 C CA  . THR D 4 107 ? 284.006 362.563 429.904 1.00 82.93  ? 107 THR B CA  1 
ATOM 4142 C C   . THR D 4 107 ? 284.606 363.244 431.125 1.00 82.93  ? 107 THR B C   1 
ATOM 4143 O O   . THR D 4 107 ? 284.677 364.473 431.175 1.00 82.93  ? 107 THR B O   1 
ATOM 4144 C CB  . THR D 4 107 ? 284.614 363.113 428.627 1.00 82.93  ? 107 THR B CB  1 
ATOM 4145 O OG1 . THR D 4 107 ? 284.037 362.446 427.502 1.00 82.93  ? 107 THR B OG1 1 
ATOM 4146 C CG2 . THR D 4 107 ? 286.104 362.896 428.624 1.00 82.93  ? 107 THR B CG2 1 
ATOM 4147 N N   . ILE D 4 108 ? 285.035 362.457 432.100 1.00 76.29  ? 108 ILE B N   1 
ATOM 4148 C CA  . ILE D 4 108 ? 285.399 362.968 433.412 1.00 76.29  ? 108 ILE B CA  1 
ATOM 4149 C C   . ILE D 4 108 ? 286.907 362.901 433.569 1.00 76.29  ? 108 ILE B C   1 
ATOM 4150 O O   . ILE D 4 108 ? 287.517 361.862 433.303 1.00 76.29  ? 108 ILE B O   1 
ATOM 4151 C CB  . ILE D 4 108 ? 284.693 362.178 434.518 1.00 76.29  ? 108 ILE B CB  1 
ATOM 4152 C CG1 . ILE D 4 108 ? 283.200 362.128 434.229 1.00 76.29  ? 108 ILE B CG1 1 
ATOM 4153 C CG2 . ILE D 4 108 ? 284.938 362.809 435.848 1.00 76.29  ? 108 ILE B CG2 1 
ATOM 4154 C CD1 . ILE D 4 108 ? 282.431 361.267 435.175 1.00 76.29  ? 108 ILE B CD1 1 
ATOM 4155 N N   . HIS D 4 109 ? 287.513 364.004 433.994 1.00 83.20  ? 109 HIS B N   1 
ATOM 4156 C CA  . HIS D 4 109 ? 288.936 364.068 434.293 1.00 83.20  ? 109 HIS B CA  1 
ATOM 4157 C C   . HIS D 4 109 ? 289.106 364.416 435.761 1.00 83.20  ? 109 HIS B C   1 
ATOM 4158 O O   . HIS D 4 109 ? 288.644 365.468 436.203 1.00 83.20  ? 109 HIS B O   1 
ATOM 4159 C CB  . HIS D 4 109 ? 289.639 365.115 433.436 1.00 83.20  ? 109 HIS B CB  1 
ATOM 4160 C CG  . HIS D 4 109 ? 289.955 364.657 432.053 1.00 83.20  ? 109 HIS B CG  1 
ATOM 4161 N ND1 . HIS D 4 109 ? 289.080 364.810 431.002 1.00 83.20  ? 109 HIS B ND1 1 
ATOM 4162 C CD2 . HIS D 4 109 ? 291.057 364.061 431.543 1.00 83.20  ? 109 HIS B CD2 1 
ATOM 4163 C CE1 . HIS D 4 109 ? 289.625 364.320 429.904 1.00 83.20  ? 109 HIS B CE1 1 
ATOM 4164 N NE2 . HIS D 4 109 ? 290.824 363.859 430.205 1.00 83.20  ? 109 HIS B NE2 1 
ATOM 4165 N N   . VAL D 4 110 ? 289.760 363.541 436.514 1.00 79.62  ? 110 VAL B N   1 
ATOM 4166 C CA  . VAL D 4 110 ? 290.073 363.783 437.915 1.00 79.62  ? 110 VAL B CA  1 
ATOM 4167 C C   . VAL D 4 110 ? 291.581 363.789 438.064 1.00 79.62  ? 110 VAL B C   1 
ATOM 4168 O O   . VAL D 4 110 ? 292.255 362.887 437.559 1.00 79.62  ? 110 VAL B O   1 
ATOM 4169 C CB  . VAL D 4 110 ? 289.449 362.717 438.826 1.00 79.62  ? 110 VAL B CB  1 
ATOM 4170 C CG1 . VAL D 4 110 ? 289.627 363.095 440.270 1.00 79.62  ? 110 VAL B CG1 1 
ATOM 4171 C CG2 . VAL D 4 110 ? 287.992 362.537 438.506 1.00 79.62  ? 110 VAL B CG2 1 
ATOM 4172 N N   . GLN D 4 111 ? 292.117 364.797 438.746 1.00 85.77  ? 111 GLN B N   1 
ATOM 4173 C CA  . GLN D 4 111 ? 293.549 364.826 439.019 1.00 85.77  ? 111 GLN B CA  1 
ATOM 4174 C C   . GLN D 4 111 ? 293.811 365.598 440.298 1.00 85.77  ? 111 GLN B C   1 
ATOM 4175 O O   . GLN D 4 111 ? 293.446 366.769 440.402 1.00 85.77  ? 111 GLN B O   1 
ATOM 4176 C CB  . GLN D 4 111 ? 294.320 365.441 437.856 1.00 85.77  ? 111 GLN B CB  1 
ATOM 4177 C CG  . GLN D 4 111 ? 293.613 366.575 437.160 1.00 85.77  ? 111 GLN B CG  1 
ATOM 4178 C CD  . GLN D 4 111 ? 294.303 366.975 435.877 1.00 85.77  ? 111 GLN B CD  1 
ATOM 4179 O OE1 . GLN D 4 111 ? 295.353 366.436 435.533 1.00 85.77  ? 111 GLN B OE1 1 
ATOM 4180 N NE2 . GLN D 4 111 ? 293.716 367.925 435.159 1.00 85.77  ? 111 GLN B NE2 1 
ATOM 4181 N N   . CYS D 4 112 ? 294.451 364.947 441.260 1.00 88.64  ? 112 CYS B N   1 
ATOM 4182 C CA  . CYS D 4 112 ? 294.907 365.596 442.477 1.00 88.64  ? 112 CYS B CA  1 
ATOM 4183 C C   . CYS D 4 112 ? 296.418 365.732 442.421 1.00 88.64  ? 112 CYS B C   1 
ATOM 4184 O O   . CYS D 4 112 ? 297.110 364.853 441.901 1.00 88.64  ? 112 CYS B O   1 
ATOM 4185 C CB  . CYS D 4 112 ? 294.482 364.816 443.718 1.00 88.64  ? 112 CYS B CB  1 
ATOM 4186 S SG  . CYS D 4 112 ? 295.293 363.235 443.968 1.00 88.64  ? 112 CYS B SG  1 
ATOM 4187 N N   . ASN D 4 113 ? 296.928 366.845 442.924 1.00 88.98  ? 113 ASN B N   1 
ATOM 4188 C CA  . ASN D 4 113 ? 298.344 367.170 442.812 1.00 88.98  ? 113 ASN B CA  1 
ATOM 4189 C C   . ASN D 4 113 ? 298.975 367.159 444.196 1.00 88.98  ? 113 ASN B C   1 
ATOM 4190 O O   . ASN D 4 113 ? 298.743 368.063 445.001 1.00 88.98  ? 113 ASN B O   1 
ATOM 4191 C CB  . ASN D 4 113 ? 298.537 368.515 442.121 1.00 88.98  ? 113 ASN B CB  1 
ATOM 4192 C CG  . ASN D 4 113 ? 297.535 369.540 442.564 1.00 88.98  ? 113 ASN B CG  1 
ATOM 4193 O OD1 . ASN D 4 113 ? 296.663 369.256 443.376 1.00 88.98  ? 113 ASN B OD1 1 
ATOM 4194 N ND2 . ASN D 4 113 ? 297.657 370.748 442.043 1.00 88.98  ? 113 ASN B ND2 1 
ATOM 4195 N N   . ALA D 4 114 ? 299.776 366.140 444.464 1.00 88.96  ? 114 ALA B N   1 
ATOM 4196 C CA  . ALA D 4 114 ? 300.535 366.051 445.695 1.00 88.96  ? 114 ALA B CA  1 
ATOM 4197 C C   . ALA D 4 114 ? 302.006 365.931 445.350 1.00 88.96  ? 114 ALA B C   1 
ATOM 4198 O O   . ALA D 4 114 ? 302.372 365.577 444.229 1.00 88.96  ? 114 ALA B O   1 
ATOM 4199 C CB  . ALA D 4 114 ? 300.105 364.857 446.543 1.00 88.96  ? 114 ALA B CB  1 
ATOM 4200 N N   . SER D 4 115 ? 302.852 366.218 446.329 1.00 89.64  ? 115 SER B N   1 
ATOM 4201 C CA  . SER D 4 115 ? 304.290 366.124 446.134 1.00 89.64  ? 115 SER B CA  1 
ATOM 4202 C C   . SER D 4 115 ? 304.731 364.676 446.320 1.00 89.64  ? 115 SER B C   1 
ATOM 4203 O O   . SER D 4 115 ? 303.916 363.758 446.430 1.00 89.64  ? 115 SER B O   1 
ATOM 4204 C CB  . SER D 4 115 ? 305.008 367.063 447.089 1.00 89.64  ? 115 SER B CB  1 
ATOM 4205 O OG  . SER D 4 115 ? 304.433 366.979 448.376 1.00 89.64  ? 115 SER B OG  1 
ATOM 4206 N N   . LYS D 4 116 ? 306.036 364.450 446.365 1.00 91.55  ? 116 LYS B N   1 
ATOM 4207 C CA  . LYS D 4 116 ? 306.538 363.099 446.544 1.00 91.55  ? 116 LYS B CA  1 
ATOM 4208 C C   . LYS D 4 116 ? 306.611 362.682 448.001 1.00 91.55  ? 116 LYS B C   1 
ATOM 4209 O O   . LYS D 4 116 ? 307.067 361.573 448.286 1.00 91.55  ? 116 LYS B O   1 
ATOM 4210 C CB  . LYS D 4 116 ? 307.916 362.961 445.908 1.00 91.55  ? 116 LYS B CB  1 
ATOM 4211 C CG  . LYS D 4 116 ? 307.866 362.617 444.442 1.00 91.55  ? 116 LYS B CG  1 
ATOM 4212 C CD  . LYS D 4 116 ? 309.144 361.949 443.991 1.00 91.55  ? 116 LYS B CD  1 
ATOM 4213 C CE  . LYS D 4 116 ? 308.992 361.407 442.587 1.00 91.55  ? 116 LYS B CE  1 
ATOM 4214 N NZ  . LYS D 4 116 ? 307.715 360.659 442.434 1.00 91.55  ? 116 LYS B NZ  1 
ATOM 4215 N N   . PHE D 4 117 ? 306.176 363.525 448.925 1.00 86.30  ? 117 PHE B N   1 
ATOM 4216 C CA  . PHE D 4 117 ? 306.262 363.220 450.341 1.00 86.30  ? 117 PHE B CA  1 
ATOM 4217 C C   . PHE D 4 117 ? 304.905 362.937 450.963 1.00 86.30  ? 117 PHE B C   1 
ATOM 4218 O O   . PHE D 4 117 ? 304.830 362.739 452.176 1.00 86.30  ? 117 PHE B O   1 
ATOM 4219 C CB  . PHE D 4 117 ? 306.948 364.367 451.082 1.00 86.30  ? 117 PHE B CB  1 
ATOM 4220 C CG  . PHE D 4 117 ? 308.405 364.518 450.747 1.00 86.30  ? 117 PHE B CG  1 
ATOM 4221 C CD1 . PHE D 4 117 ? 308.809 365.265 449.658 1.00 86.30  ? 117 PHE B CD1 1 
ATOM 4222 C CD2 . PHE D 4 117 ? 309.369 363.917 451.523 1.00 86.30  ? 117 PHE B CD2 1 
ATOM 4223 C CE1 . PHE D 4 117 ? 310.146 365.399 449.353 1.00 86.30  ? 117 PHE B CE1 1 
ATOM 4224 C CE2 . PHE D 4 117 ? 310.704 364.051 451.221 1.00 86.30  ? 117 PHE B CE2 1 
ATOM 4225 C CZ  . PHE D 4 117 ? 311.088 364.792 450.137 1.00 86.30  ? 117 PHE B CZ  1 
ATOM 4226 N N   . HIS D 4 118 ? 303.841 362.922 450.170 1.00 83.19  ? 118 HIS B N   1 
ATOM 4227 C CA  . HIS D 4 118 ? 302.511 362.556 450.632 1.00 83.19  ? 118 HIS B CA  1 
ATOM 4228 C C   . HIS D 4 118 ? 302.216 361.108 450.265 1.00 83.19  ? 118 HIS B C   1 
ATOM 4229 O O   . HIS D 4 118 ? 302.899 360.501 449.444 1.00 83.19  ? 118 HIS B O   1 
ATOM 4230 C CB  . HIS D 4 118 ? 301.455 363.476 450.025 1.00 83.19  ? 118 HIS B CB  1 
ATOM 4231 C CG  . HIS D 4 118 ? 301.521 364.887 450.513 1.00 83.19  ? 118 HIS B CG  1 
ATOM 4232 N ND1 . HIS D 4 118 ? 302.296 365.849 449.905 1.00 83.19  ? 118 HIS B ND1 1 
ATOM 4233 C CD2 . HIS D 4 118 ? 300.892 365.506 451.537 1.00 83.19  ? 118 HIS B CD2 1 
ATOM 4234 C CE1 . HIS D 4 118 ? 302.148 366.996 450.540 1.00 83.19  ? 118 HIS B CE1 1 
ATOM 4235 N NE2 . HIS D 4 118 ? 301.301 366.815 451.535 1.00 83.19  ? 118 HIS B NE2 1 
ATOM 4236 N N   . GLN D 4 119 ? 301.173 360.559 450.876 1.00 84.25  ? 119 GLN B N   1 
ATOM 4237 C CA  . GLN D 4 119 ? 300.806 359.177 450.616 1.00 84.25  ? 119 GLN B CA  1 
ATOM 4238 C C   . GLN D 4 119 ? 299.308 359.004 450.793 1.00 84.25  ? 119 GLN B C   1 
ATOM 4239 O O   . GLN D 4 119 ? 298.693 359.660 451.631 1.00 84.25  ? 119 GLN B O   1 
ATOM 4240 C CB  . GLN D 4 119 ? 301.559 358.223 451.538 1.00 84.25  ? 119 GLN B CB  1 
ATOM 4241 C CG  . GLN D 4 119 ? 301.529 358.620 452.991 1.00 84.25  ? 119 GLN B CG  1 
ATOM 4242 C CD  . GLN D 4 119 ? 302.322 357.675 453.862 1.00 84.25  ? 119 GLN B CD  1 
ATOM 4243 O OE1 . GLN D 4 119 ? 301.755 356.857 454.581 1.00 84.25  ? 119 GLN B OE1 1 
ATOM 4244 N NE2 . GLN D 4 119 ? 303.640 357.783 453.805 1.00 84.25  ? 119 GLN B NE2 1 
ATOM 4245 N N   . GLY D 4 120 ? 298.732 358.112 450.006 1.00 79.94  ? 120 GLY B N   1 
ATOM 4246 C CA  . GLY D 4 120 ? 297.306 357.866 450.068 1.00 79.94  ? 120 GLY B CA  1 
ATOM 4247 C C   . GLY D 4 120 ? 296.835 357.171 448.812 1.00 79.94  ? 120 GLY B C   1 
ATOM 4248 O O   . GLY D 4 120 ? 297.610 356.903 447.899 1.00 79.94  ? 120 GLY B O   1 
ATOM 4249 N N   . CYS D 4 121 ? 295.535 356.887 448.783 1.00 78.22  ? 121 CYS B N   1 
ATOM 4250 C CA  . CYS D 4 121 ? 294.941 356.195 447.647 1.00 78.22  ? 121 CYS B CA  1 
ATOM 4251 C C   . CYS D 4 121 ? 293.459 356.505 447.550 1.00 78.22  ? 121 CYS B C   1 
ATOM 4252 O O   . CYS D 4 121 ? 292.730 356.347 448.530 1.00 78.22  ? 121 CYS B O   1 
ATOM 4253 C CB  . CYS D 4 121 ? 295.137 354.688 447.764 1.00 78.22  ? 121 CYS B CB  1 
ATOM 4254 S SG  . CYS D 4 121 ? 294.949 353.812 446.209 1.00 78.22  ? 121 CYS B SG  1 
ATOM 4255 N N   . LEU D 4 122 ? 293.016 356.912 446.367 1.00 75.38  ? 122 LEU B N   1 
ATOM 4256 C CA  . LEU D 4 122 ? 291.620 357.216 446.105 1.00 75.38  ? 122 LEU B CA  1 
ATOM 4257 C C   . LEU D 4 122 ? 290.991 356.117 445.265 1.00 75.38  ? 122 LEU B C   1 
ATOM 4258 O O   . LEU D 4 122 ? 291.680 355.283 444.684 1.00 75.38  ? 122 LEU B O   1 
ATOM 4259 C CB  . LEU D 4 122 ? 291.475 358.543 445.365 1.00 75.38  ? 122 LEU B CB  1 
ATOM 4260 C CG  . LEU D 4 122 ? 291.785 359.825 446.112 1.00 75.38  ? 122 LEU B CG  1 
ATOM 4261 C CD1 . LEU D 4 122 ? 291.439 360.991 445.234 1.00 75.38  ? 122 LEU B CD1 1 
ATOM 4262 C CD2 . LEU D 4 122 ? 290.990 359.876 447.374 1.00 75.38  ? 122 LEU B CD2 1 
ATOM 4263 N N   . LEU D 4 123 ? 289.667 356.137 445.197 1.00 71.65  ? 123 LEU B N   1 
ATOM 4264 C CA  . LEU D 4 123 ? 288.913 355.295 444.280 1.00 71.65  ? 123 LEU B CA  1 
ATOM 4265 C C   . LEU D 4 123 ? 287.915 356.178 443.559 1.00 71.65  ? 123 LEU B C   1 
ATOM 4266 O O   . LEU D 4 123 ? 287.040 356.770 444.194 1.00 71.65  ? 123 LEU B O   1 
ATOM 4267 C CB  . LEU D 4 123 ? 288.192 354.167 445.013 1.00 71.65  ? 123 LEU B CB  1 
ATOM 4268 C CG  . LEU D 4 123 ? 287.094 353.449 444.231 1.00 71.65  ? 123 LEU B CG  1 
ATOM 4269 C CD1 . LEU D 4 123 ? 287.684 352.639 443.114 1.00 71.65  ? 123 LEU B CD1 1 
ATOM 4270 C CD2 . LEU D 4 123 ? 286.290 352.561 445.139 1.00 71.65  ? 123 LEU B CD2 1 
ATOM 4271 N N   . VAL D 4 124 ? 288.053 356.281 442.248 1.00 72.76  ? 124 VAL B N   1 
ATOM 4272 C CA  . VAL D 4 124 ? 287.184 357.112 441.431 1.00 72.76  ? 124 VAL B CA  1 
ATOM 4273 C C   . VAL D 4 124 ? 286.243 356.187 440.684 1.00 72.76  ? 124 VAL B C   1 
ATOM 4274 O O   . VAL D 4 124 ? 286.658 355.502 439.746 1.00 72.76  ? 124 VAL B O   1 
ATOM 4275 C CB  . VAL D 4 124 ? 287.985 357.977 440.460 1.00 72.76  ? 124 VAL B CB  1 
ATOM 4276 C CG1 . VAL D 4 124 ? 287.056 358.815 439.637 1.00 72.76  ? 124 VAL B CG1 1 
ATOM 4277 C CG2 . VAL D 4 124 ? 288.933 358.844 441.222 1.00 72.76  ? 124 VAL B CG2 1 
ATOM 4278 N N   . VAL D 4 125 ? 284.979 356.159 441.089 1.00 71.20  ? 125 VAL B N   1 
ATOM 4279 C CA  . VAL D 4 125 ? 283.991 355.280 440.484 1.00 71.20  ? 125 VAL B CA  1 
ATOM 4280 C C   . VAL D 4 125 ? 282.852 356.145 439.967 1.00 71.20  ? 125 VAL B C   1 
ATOM 4281 O O   . VAL D 4 125 ? 282.703 357.300 440.374 1.00 71.20  ? 125 VAL B O   1 
ATOM 4282 C CB  . VAL D 4 125 ? 283.505 354.218 441.493 1.00 71.20  ? 125 VAL B CB  1 
ATOM 4283 C CG1 . VAL D 4 125 ? 282.452 354.772 442.403 1.00 71.20  ? 125 VAL B CG1 1 
ATOM 4284 C CG2 . VAL D 4 125 ? 283.022 352.979 440.798 1.00 71.20  ? 125 VAL B CG2 1 
ATOM 4285 N N   . CYS D 4 126 ? 282.076 355.608 439.029 1.00 79.93  ? 126 CYS B N   1 
ATOM 4286 C CA  . CYS D 4 126 ? 280.953 356.331 438.439 1.00 79.93  ? 126 CYS B CA  1 
ATOM 4287 C C   . CYS D 4 126 ? 279.745 355.402 438.417 1.00 79.93  ? 126 CYS B C   1 
ATOM 4288 O O   . CYS D 4 126 ? 279.584 354.602 437.494 1.00 79.93  ? 126 CYS B O   1 
ATOM 4289 C CB  . CYS D 4 126 ? 281.300 356.828 437.047 1.00 79.93  ? 126 CYS B CB  1 
ATOM 4290 S SG  . CYS D 4 126 ? 279.906 357.523 436.156 1.00 79.93  ? 126 CYS B SG  1 
ATOM 4291 N N   . VAL D 4 127 ? 278.890 355.521 439.424 1.00 79.32  ? 127 VAL B N   1 
ATOM 4292 C CA  . VAL D 4 127 ? 277.770 354.611 439.636 1.00 79.32  ? 127 VAL B CA  1 
ATOM 4293 C C   . VAL D 4 127 ? 276.563 355.038 438.815 1.00 79.32  ? 127 VAL B C   1 
ATOM 4294 O O   . VAL D 4 127 ? 276.117 356.185 438.941 1.00 79.32  ? 127 VAL B O   1 
ATOM 4295 C CB  . VAL D 4 127 ? 277.390 354.558 441.119 1.00 79.32  ? 127 VAL B CB  1 
ATOM 4296 C CG1 . VAL D 4 127 ? 276.491 353.396 441.375 1.00 79.32  ? 127 VAL B CG1 1 
ATOM 4297 C CG2 . VAL D 4 127 ? 278.621 354.474 441.967 1.00 79.32  ? 127 VAL B CG2 1 
ATOM 4298 N N   . PRO D 4 128 ? 275.998 354.177 437.983 1.00 80.80  ? 128 PRO B N   1 
ATOM 4299 C CA  . PRO D 4 128 ? 274.715 354.510 437.355 1.00 80.80  ? 128 PRO B CA  1 
ATOM 4300 C C   . PRO D 4 128 ? 273.535 354.108 438.221 1.00 80.80  ? 128 PRO B C   1 
ATOM 4301 O O   . PRO D 4 128 ? 273.503 352.988 438.740 1.00 80.80  ? 128 PRO B O   1 
ATOM 4302 C CB  . PRO D 4 128 ? 274.754 353.722 436.046 1.00 80.80  ? 128 PRO B CB  1 
ATOM 4303 C CG  . PRO D 4 128 ? 275.633 352.590 436.320 1.00 80.80  ? 128 PRO B CG  1 
ATOM 4304 C CD  . PRO D 4 128 ? 276.618 352.998 437.371 1.00 80.80  ? 128 PRO B CD  1 
ATOM 4305 N N   . GLU D 4 129 ? 272.577 355.028 438.379 1.00 92.37  ? 129 GLU B N   1 
ATOM 4306 C CA  . GLU D 4 129 ? 271.360 354.856 439.179 1.00 92.37  ? 129 GLU B CA  1 
ATOM 4307 C C   . GLU D 4 129 ? 271.688 354.499 440.628 1.00 92.37  ? 129 GLU B C   1 
ATOM 4308 O O   . GLU D 4 129 ? 271.408 353.404 441.109 1.00 92.37  ? 129 GLU B O   1 
ATOM 4309 C CB  . GLU D 4 129 ? 270.426 353.821 438.551 1.00 92.37  ? 129 GLU B CB  1 
ATOM 4310 C CG  . GLU D 4 129 ? 270.082 354.118 437.114 1.00 92.37  ? 129 GLU B CG  1 
ATOM 4311 C CD  . GLU D 4 129 ? 268.809 354.918 436.979 1.00 92.37  ? 129 GLU B CD  1 
ATOM 4312 O OE1 . GLU D 4 129 ? 267.992 354.884 437.917 1.00 92.37  ? 129 GLU B OE1 1 
ATOM 4313 O OE2 . GLU D 4 129 ? 268.621 355.582 435.941 1.00 92.37  ? 129 GLU B OE2 1 
ATOM 4314 N N   . ALA D 4 130 ? 272.312 355.449 441.317 1.00 91.62  ? 130 ALA B N   1 
ATOM 4315 C CA  . ALA D 4 130 ? 272.722 355.247 442.703 1.00 91.62  ? 130 ALA B CA  1 
ATOM 4316 C C   . ALA D 4 130 ? 271.630 355.783 443.620 1.00 91.62  ? 130 ALA B C   1 
ATOM 4317 O O   . ALA D 4 130 ? 271.658 356.923 444.081 1.00 91.62  ? 130 ALA B O   1 
ATOM 4318 C CB  . ALA D 4 130 ? 274.057 355.921 442.970 1.00 91.62  ? 130 ALA B CB  1 
ATOM 4319 N N   . GLU D 4 131 ? 270.654 354.930 443.894 1.00 98.98  ? 131 GLU B N   1 
ATOM 4320 C CA  . GLU D 4 131 ? 269.541 355.296 444.758 1.00 98.98  ? 131 GLU B CA  1 
ATOM 4321 C C   . GLU D 4 131 ? 269.983 355.223 446.208 1.00 98.98  ? 131 GLU B C   1 
ATOM 4322 O O   . GLU D 4 131 ? 270.420 354.168 446.669 1.00 98.98  ? 131 GLU B O   1 
ATOM 4323 C CB  . GLU D 4 131 ? 268.363 354.365 444.508 1.00 98.98  ? 131 GLU B CB  1 
ATOM 4324 C CG  . GLU D 4 131 ? 267.102 354.751 445.225 1.00 98.98  ? 131 GLU B CG  1 
ATOM 4325 C CD  . GLU D 4 131 ? 265.923 353.920 444.780 1.00 98.98  ? 131 GLU B CD  1 
ATOM 4326 O OE1 . GLU D 4 131 ? 265.027 353.657 445.607 1.00 98.98  ? 131 GLU B OE1 1 
ATOM 4327 O OE2 . GLU D 4 131 ? 265.892 353.528 443.596 1.00 98.98  ? 131 GLU B OE2 1 
ATOM 4328 N N   . MET D 4 132 ? 269.869 356.329 446.930 1.00 99.69  ? 132 MET B N   1 
ATOM 4329 C CA  . MET D 4 132 ? 270.336 356.392 448.305 1.00 99.69  ? 132 MET B CA  1 
ATOM 4330 C C   . MET D 4 132 ? 269.181 356.212 449.280 1.00 99.69  ? 132 MET B C   1 
ATOM 4331 O O   . MET D 4 132 ? 268.010 356.321 448.925 1.00 99.69  ? 132 MET B O   1 
ATOM 4332 C CB  . MET D 4 132 ? 271.053 357.714 448.563 1.00 99.69  ? 132 MET B CB  1 
ATOM 4333 C CG  . MET D 4 132 ? 272.175 357.962 447.591 1.00 99.69  ? 132 MET B CG  1 
ATOM 4334 S SD  . MET D 4 132 ? 273.462 359.005 448.269 1.00 99.69  ? 132 MET B SD  1 
ATOM 4335 C CE  . MET D 4 132 ? 274.706 358.817 447.005 1.00 99.69  ? 132 MET B CE  1 
ATOM 4336 N N   . GLY D 4 133 ? 269.529 355.932 450.529 1.00 98.28  ? 133 GLY B N   1 
ATOM 4337 C CA  . GLY D 4 133 ? 268.549 355.618 451.547 1.00 98.28  ? 133 GLY B CA  1 
ATOM 4338 C C   . GLY D 4 133 ? 268.530 356.664 452.641 1.00 98.28  ? 133 GLY B C   1 
ATOM 4339 O O   . GLY D 4 133 ? 269.568 357.198 453.028 1.00 98.28  ? 133 GLY B O   1 
ATOM 4340 N N   . CYS D 4 134 ? 267.336 356.945 453.146 1.00 103.60 ? 134 CYS B N   1 
ATOM 4341 C CA  . CYS D 4 134 ? 267.179 357.980 454.151 1.00 103.60 ? 134 CYS B CA  1 
ATOM 4342 C C   . CYS D 4 134 ? 267.654 357.495 455.511 1.00 103.60 ? 134 CYS B C   1 
ATOM 4343 O O   . CYS D 4 134 ? 267.827 356.299 455.748 1.00 103.60 ? 134 CYS B O   1 
ATOM 4344 C CB  . CYS D 4 134 ? 265.726 358.422 454.255 1.00 103.60 ? 134 CYS B CB  1 
ATOM 4345 S SG  . CYS D 4 134 ? 265.464 359.678 455.506 1.00 103.60 ? 134 CYS B SG  1 
ATOM 4346 N N   . SER D 4 135 ? 267.873 358.452 456.412 1.00 102.75 ? 135 SER B N   1 
ATOM 4347 C CA  . SER D 4 135 ? 268.284 358.100 457.764 1.00 102.75 ? 135 SER B CA  1 
ATOM 4348 C C   . SER D 4 135 ? 267.110 357.571 458.563 1.00 102.75 ? 135 SER B C   1 
ATOM 4349 O O   . SER D 4 135 ? 267.233 356.564 459.267 1.00 102.75 ? 135 SER B O   1 
ATOM 4350 C CB  . SER D 4 135 ? 268.891 359.306 458.463 1.00 102.75 ? 135 SER B CB  1 
ATOM 4351 O OG  . SER D 4 135 ? 267.879 360.059 459.091 1.00 102.75 ? 135 SER B OG  1 
ATOM 4352 N N   . ASN D 4 136 ? 265.970 358.241 458.476 1.00 105.90 ? 136 ASN B N   1 
ATOM 4353 C CA  . ASN D 4 136 ? 264.748 357.717 459.061 1.00 105.90 ? 136 ASN B CA  1 
ATOM 4354 C C   . ASN D 4 136 ? 264.284 356.518 458.251 1.00 105.90 ? 136 ASN B C   1 
ATOM 4355 O O   . ASN D 4 136 ? 264.389 356.514 457.023 1.00 105.90 ? 136 ASN B O   1 
ATOM 4356 C CB  . ASN D 4 136 ? 263.675 358.797 459.086 1.00 105.90 ? 136 ASN B CB  1 
ATOM 4357 C CG  . ASN D 4 136 ? 262.460 358.385 459.867 1.00 105.90 ? 136 ASN B CG  1 
ATOM 4358 O OD1 . ASN D 4 136 ? 262.497 357.433 460.637 1.00 105.90 ? 136 ASN B OD1 1 
ATOM 4359 N ND2 . ASN D 4 136 ? 261.368 359.111 459.680 1.00 105.90 ? 136 ASN B ND2 1 
ATOM 4360 N N   . LEU D 4 137 ? 263.778 355.499 458.931 1.00 104.94 ? 137 LEU B N   1 
ATOM 4361 C CA  . LEU D 4 137 ? 263.450 354.249 458.261 1.00 104.94 ? 137 LEU B CA  1 
ATOM 4362 C C   . LEU D 4 137 ? 262.176 354.313 457.438 1.00 104.94 ? 137 LEU B C   1 
ATOM 4363 O O   . LEU D 4 137 ? 261.914 353.379 456.678 1.00 104.94 ? 137 LEU B O   1 
ATOM 4364 C CB  . LEU D 4 137 ? 263.326 353.116 459.275 1.00 104.94 ? 137 LEU B CB  1 
ATOM 4365 C CG  . LEU D 4 137 ? 264.539 352.211 459.453 1.00 104.94 ? 137 LEU B CG  1 
ATOM 4366 C CD1 . LEU D 4 137 ? 264.830 351.544 458.137 1.00 104.94 ? 137 LEU B CD1 1 
ATOM 4367 C CD2 . LEU D 4 137 ? 265.750 352.970 459.949 1.00 104.94 ? 137 LEU B CD2 1 
ATOM 4368 N N   . ASN D 4 138 ? 261.378 355.371 457.559 1.00 108.10 ? 138 ASN B N   1 
ATOM 4369 C CA  . ASN D 4 138 ? 260.106 355.432 456.859 1.00 108.10 ? 138 ASN B CA  1 
ATOM 4370 C C   . ASN D 4 138 ? 260.058 356.463 455.744 1.00 108.10 ? 138 ASN B C   1 
ATOM 4371 O O   . ASN D 4 138 ? 259.245 356.312 454.830 1.00 108.10 ? 138 ASN B O   1 
ATOM 4372 C CB  . ASN D 4 138 ? 258.969 355.728 457.843 1.00 108.10 ? 138 ASN B CB  1 
ATOM 4373 C CG  . ASN D 4 138 ? 259.070 354.909 459.101 1.00 108.10 ? 138 ASN B CG  1 
ATOM 4374 O OD1 . ASN D 4 138 ? 258.794 353.714 459.100 1.00 108.10 ? 138 ASN B OD1 1 
ATOM 4375 N ND2 . ASN D 4 138 ? 259.464 355.550 460.190 1.00 108.10 ? 138 ASN B ND2 1 
ATOM 4376 N N   . ASN D 4 139 ? 260.891 357.490 455.789 1.00 108.63 ? 139 ASN B N   1 
ATOM 4377 C CA  . ASN D 4 139 ? 260.802 358.575 454.831 1.00 108.63 ? 139 ASN B CA  1 
ATOM 4378 C C   . ASN D 4 139 ? 261.853 358.415 453.742 1.00 108.63 ? 139 ASN B C   1 
ATOM 4379 O O   . ASN D 4 139 ? 262.620 357.455 453.711 1.00 108.63 ? 139 ASN B O   1 
ATOM 4380 C CB  . ASN D 4 139 ? 260.949 359.916 455.539 1.00 108.63 ? 139 ASN B CB  1 
ATOM 4381 C CG  . ASN D 4 139 ? 259.984 360.065 456.676 1.00 108.63 ? 139 ASN B CG  1 
ATOM 4382 O OD1 . ASN D 4 139 ? 259.079 359.251 456.840 1.00 108.63 ? 139 ASN B OD1 1 
ATOM 4383 N ND2 . ASN D 4 139 ? 260.164 361.105 457.475 1.00 108.63 ? 139 ASN B ND2 1 
ATOM 4384 N N   . THR D 4 140 ? 261.862 359.366 452.826 1.00 106.04 ? 140 THR B N   1 
ATOM 4385 C CA  . THR D 4 140 ? 262.757 359.513 451.699 1.00 106.04 ? 140 THR B CA  1 
ATOM 4386 C C   . THR D 4 140 ? 263.492 360.843 451.802 1.00 106.04 ? 140 THR B C   1 
ATOM 4387 O O   . THR D 4 140 ? 262.910 361.826 452.266 1.00 106.04 ? 140 THR B O   1 
ATOM 4388 C CB  . THR D 4 140 ? 261.977 359.472 450.383 1.00 106.04 ? 140 THR B CB  1 
ATOM 4389 O OG1 . THR D 4 140 ? 261.126 360.620 450.309 1.00 106.04 ? 140 THR B OG1 1 
ATOM 4390 C CG2 . THR D 4 140 ? 261.132 358.219 450.302 1.00 106.04 ? 140 THR B CG2 1 
ATOM 4391 N N   . PRO D 4 141 ? 264.755 360.917 451.382 1.00 106.31 ? 141 PRO B N   1 
ATOM 4392 C CA  . PRO D 4 141 ? 265.523 362.152 451.568 1.00 106.31 ? 141 PRO B CA  1 
ATOM 4393 C C   . PRO D 4 141 ? 265.037 363.282 450.678 1.00 106.31 ? 141 PRO B C   1 
ATOM 4394 O O   . PRO D 4 141 ? 264.540 363.066 449.572 1.00 106.31 ? 141 PRO B O   1 
ATOM 4395 C CB  . PRO D 4 141 ? 266.945 361.737 451.194 1.00 106.31 ? 141 PRO B CB  1 
ATOM 4396 C CG  . PRO D 4 141 ? 266.760 360.615 450.275 1.00 106.31 ? 141 PRO B CG  1 
ATOM 4397 C CD  . PRO D 4 141 ? 265.589 359.858 450.795 1.00 106.31 ? 141 PRO B CD  1 
ATOM 4398 N N   . GLU D 4 142 ? 265.189 364.503 451.179 1.00 112.73 ? 142 GLU B N   1 
ATOM 4399 C CA  . GLU D 4 142 ? 264.709 365.679 450.474 1.00 112.73 ? 142 GLU B CA  1 
ATOM 4400 C C   . GLU D 4 142 ? 265.647 366.026 449.324 1.00 112.73 ? 142 GLU B C   1 
ATOM 4401 O O   . GLU D 4 142 ? 266.687 365.397 449.123 1.00 112.73 ? 142 GLU B O   1 
ATOM 4402 C CB  . GLU D 4 142 ? 264.561 366.851 451.436 1.00 112.73 ? 142 GLU B CB  1 
ATOM 4403 C CG  . GLU D 4 142 ? 265.873 367.403 451.936 1.00 112.73 ? 142 GLU B CG  1 
ATOM 4404 C CD  . GLU D 4 142 ? 265.697 368.289 453.152 1.00 112.73 ? 142 GLU B CD  1 
ATOM 4405 O OE1 . GLU D 4 142 ? 266.620 368.345 453.990 1.00 112.73 ? 142 GLU B OE1 1 
ATOM 4406 O OE2 . GLU D 4 142 ? 264.633 368.929 453.272 1.00 112.73 ? 142 GLU B OE2 1 
ATOM 4407 N N   . PHE D 4 143 ? 265.278 367.050 448.553 1.00 108.91 ? 143 PHE B N   1 
ATOM 4408 C CA  . PHE D 4 143 ? 266.018 367.338 447.331 1.00 108.91 ? 143 PHE B CA  1 
ATOM 4409 C C   . PHE D 4 143 ? 267.339 368.029 447.627 1.00 108.91 ? 143 PHE B C   1 
ATOM 4410 O O   . PHE D 4 143 ? 268.345 367.761 446.962 1.00 108.91 ? 143 PHE B O   1 
ATOM 4411 C CB  . PHE D 4 143 ? 265.179 368.194 446.392 1.00 108.91 ? 143 PHE B CB  1 
ATOM 4412 C CG  . PHE D 4 143 ? 265.965 368.793 445.271 1.00 108.91 ? 143 PHE B CG  1 
ATOM 4413 C CD1 . PHE D 4 143 ? 266.556 367.983 444.316 1.00 108.91 ? 143 PHE B CD1 1 
ATOM 4414 C CD2 . PHE D 4 143 ? 266.129 370.160 445.178 1.00 108.91 ? 143 PHE B CD2 1 
ATOM 4415 C CE1 . PHE D 4 143 ? 267.290 368.529 443.285 1.00 108.91 ? 143 PHE B CE1 1 
ATOM 4416 C CE2 . PHE D 4 143 ? 266.861 370.714 444.147 1.00 108.91 ? 143 PHE B CE2 1 
ATOM 4417 C CZ  . PHE D 4 143 ? 267.441 369.895 443.200 1.00 108.91 ? 143 PHE B CZ  1 
ATOM 4418 N N   . SER D 4 144 ? 267.362 368.912 448.619 1.00 107.56 ? 144 SER B N   1 
ATOM 4419 C CA  . SER D 4 144 ? 268.563 369.678 448.920 1.00 107.56 ? 144 SER B CA  1 
ATOM 4420 C C   . SER D 4 144 ? 269.668 368.845 449.546 1.00 107.56 ? 144 SER B C   1 
ATOM 4421 O O   . SER D 4 144 ? 270.811 369.304 449.588 1.00 107.56 ? 144 SER B O   1 
ATOM 4422 C CB  . SER D 4 144 ? 268.229 370.837 449.852 1.00 107.56 ? 144 SER B CB  1 
ATOM 4423 O OG  . SER D 4 144 ? 269.388 371.262 450.541 1.00 107.56 ? 144 SER B OG  1 
ATOM 4424 N N   . GLU D 4 145 ? 269.363 367.649 450.037 1.00 105.33 ? 145 GLU B N   1 
ATOM 4425 C CA  . GLU D 4 145 ? 270.367 366.825 450.682 1.00 105.33 ? 145 GLU B CA  1 
ATOM 4426 C C   . GLU D 4 145 ? 270.890 365.706 449.799 1.00 105.33 ? 145 GLU B C   1 
ATOM 4427 O O   . GLU D 4 145 ? 271.870 365.059 450.173 1.00 105.33 ? 145 GLU B O   1 
ATOM 4428 C CB  . GLU D 4 145 ? 269.814 366.229 451.976 1.00 105.33 ? 145 GLU B CB  1 
ATOM 4429 C CG  . GLU D 4 145 ? 270.203 366.998 453.234 1.00 105.33 ? 145 GLU B CG  1 
ATOM 4430 C CD  . GLU D 4 145 ? 271.669 366.844 453.646 1.00 105.33 ? 145 GLU B CD  1 
ATOM 4431 O OE1 . GLU D 4 145 ? 272.419 366.053 453.034 1.00 105.33 ? 145 GLU B OE1 1 
ATOM 4432 O OE2 . GLU D 4 145 ? 272.078 367.531 454.605 1.00 105.33 ? 145 GLU B OE2 1 
ATOM 4433 N N   . LEU D 4 146 ? 270.264 365.444 448.659 1.00 98.21  ? 146 LEU B N   1 
ATOM 4434 C CA  . LEU D 4 146 ? 270.825 364.469 447.737 1.00 98.21  ? 146 LEU B CA  1 
ATOM 4435 C C   . LEU D 4 146 ? 271.887 365.071 446.842 1.00 98.21  ? 146 LEU B C   1 
ATOM 4436 O O   . LEU D 4 146 ? 272.936 364.458 446.625 1.00 98.21  ? 146 LEU B O   1 
ATOM 4437 C CB  . LEU D 4 146 ? 269.732 363.856 446.870 1.00 98.21  ? 146 LEU B CB  1 
ATOM 4438 C CG  . LEU D 4 146 ? 268.929 362.753 447.534 1.00 98.21  ? 146 LEU B CG  1 
ATOM 4439 C CD1 . LEU D 4 146 ? 267.822 362.312 446.616 1.00 98.21  ? 146 LEU B CD1 1 
ATOM 4440 C CD2 . LEU D 4 146 ? 269.840 361.598 447.842 1.00 98.21  ? 146 LEU B CD2 1 
ATOM 4441 N N   . SER D 4 147 ? 271.644 366.261 446.316 1.00 103.21 ? 147 SER B N   1 
ATOM 4442 C CA  . SER D 4 147 ? 272.551 366.857 445.353 1.00 103.21 ? 147 SER B CA  1 
ATOM 4443 C C   . SER D 4 147 ? 272.738 368.324 445.675 1.00 103.21 ? 147 SER B C   1 
ATOM 4444 O O   . SER D 4 147 ? 271.772 369.089 445.671 1.00 103.21 ? 147 SER B O   1 
ATOM 4445 C CB  . SER D 4 147 ? 272.012 366.711 443.935 1.00 103.21 ? 147 SER B CB  1 
ATOM 4446 O OG  . SER D 4 147 ? 271.132 367.778 443.641 1.00 103.21 ? 147 SER B OG  1 
ATOM 4447 N N   . GLY D 4 148 ? 273.980 368.717 445.939 1.00 107.53 ? 148 GLY B N   1 
ATOM 4448 C CA  . GLY D 4 148 ? 274.328 370.115 446.067 1.00 107.53 ? 148 GLY B CA  1 
ATOM 4449 C C   . GLY D 4 148 ? 274.581 370.677 444.682 1.00 107.53 ? 148 GLY B C   1 
ATOM 4450 O O   . GLY D 4 148 ? 275.334 370.098 443.894 1.00 107.53 ? 148 GLY B O   1 
ATOM 4451 N N   . GLY D 4 149 ? 273.916 371.790 444.384 1.00 111.34 ? 149 GLY B N   1 
ATOM 4452 C CA  . GLY D 4 149 ? 274.099 372.469 443.118 1.00 111.34 ? 149 GLY B CA  1 
ATOM 4453 C C   . GLY D 4 149 ? 275.505 373.005 442.982 1.00 111.34 ? 149 GLY B C   1 
ATOM 4454 O O   . GLY D 4 149 ? 275.892 373.918 443.718 1.00 111.34 ? 149 GLY B O   1 
ATOM 4455 N N   . ASP D 4 150 ? 276.263 372.425 442.038 1.00 110.63 ? 150 ASP B N   1 
ATOM 4456 C CA  . ASP D 4 150 ? 277.704 372.576 441.799 1.00 110.63 ? 150 ASP B CA  1 
ATOM 4457 C C   . ASP D 4 150 ? 278.539 372.649 443.074 1.00 110.63 ? 150 ASP B C   1 
ATOM 4458 O O   . ASP D 4 150 ? 279.474 373.449 443.172 1.00 110.63 ? 150 ASP B O   1 
ATOM 4459 C CB  . ASP D 4 150 ? 278.012 373.775 440.880 1.00 110.63 ? 150 ASP B CB  1 
ATOM 4460 C CG  . ASP D 4 150 ? 277.383 375.078 441.335 1.00 110.63 ? 150 ASP B CG  1 
ATOM 4461 O OD1 . ASP D 4 150 ? 277.845 375.659 442.339 1.00 110.63 ? 150 ASP B OD1 1 
ATOM 4462 O OD2 . ASP D 4 150 ? 276.421 375.528 440.677 1.00 110.63 ? 150 ASP B OD2 1 
ATOM 4463 N N   . SER D 4 151 ? 278.225 371.794 444.042 1.00 103.81 ? 151 SER B N   1 
ATOM 4464 C CA  . SER D 4 151 ? 278.957 371.720 445.296 1.00 103.81 ? 151 SER B CA  1 
ATOM 4465 C C   . SER D 4 151 ? 278.943 370.278 445.768 1.00 103.81 ? 151 SER B C   1 
ATOM 4466 O O   . SER D 4 151 ? 277.902 369.620 445.719 1.00 103.81 ? 151 SER B O   1 
ATOM 4467 C CB  . SER D 4 151 ? 278.344 372.635 446.355 1.00 103.81 ? 151 SER B CB  1 
ATOM 4468 O OG  . SER D 4 151 ? 279.035 372.511 447.582 1.00 103.81 ? 151 SER B OG  1 
ATOM 4469 N N   . ALA D 4 152 ? 280.091 369.792 446.216 1.00 87.99  ? 152 ALA B N   1 
ATOM 4470 C CA  . ALA D 4 152 ? 280.237 368.387 446.554 1.00 87.99  ? 152 ALA B CA  1 
ATOM 4471 C C   . ALA D 4 152 ? 279.618 368.093 447.906 1.00 87.99  ? 152 ALA B C   1 
ATOM 4472 O O   . ALA D 4 152 ? 279.886 368.794 448.882 1.00 87.99  ? 152 ALA B O   1 
ATOM 4473 C CB  . ALA D 4 152 ? 281.710 368.003 446.573 1.00 87.99  ? 152 ALA B CB  1 
ATOM 4474 N N   . ARG D 4 153 ? 278.793 367.059 447.964 1.00 85.80  ? 153 ARG B N   1 
ATOM 4475 C CA  . ARG D 4 153 ? 278.332 366.560 449.245 1.00 85.80  ? 153 ARG B CA  1 
ATOM 4476 C C   . ARG D 4 153 ? 279.388 365.644 449.843 1.00 85.80  ? 153 ARG B C   1 
ATOM 4477 O O   . ARG D 4 153 ? 280.237 365.109 449.135 1.00 85.80  ? 153 ARG B O   1 
ATOM 4478 C CB  . ARG D 4 153 ? 277.014 365.818 449.085 1.00 85.80  ? 153 ARG B CB  1 
ATOM 4479 C CG  . ARG D 4 153 ? 275.828 366.735 448.979 1.00 85.80  ? 153 ARG B CG  1 
ATOM 4480 C CD  . ARG D 4 153 ? 275.656 367.518 450.253 1.00 85.80  ? 153 ARG B CD  1 
ATOM 4481 N NE  . ARG D 4 153 ? 274.507 368.405 450.173 1.00 85.80  ? 153 ARG B NE  1 
ATOM 4482 C CZ  . ARG D 4 153 ? 274.559 369.643 449.702 1.00 85.80  ? 153 ARG B CZ  1 
ATOM 4483 N NH1 . ARG D 4 153 ? 273.463 370.384 449.661 1.00 85.80  ? 153 ARG B NH1 1 
ATOM 4484 N NH2 . ARG D 4 153 ? 275.705 370.141 449.275 1.00 85.80  ? 153 ARG B NH2 1 
ATOM 4485 N N   . MET D 4 154 ? 279.336 365.468 451.156 1.00 82.62  ? 154 MET B N   1 
ATOM 4486 C CA  . MET D 4 154 ? 280.361 364.725 451.869 1.00 82.62  ? 154 MET B CA  1 
ATOM 4487 C C   . MET D 4 154 ? 279.768 363.520 452.576 1.00 82.62  ? 154 MET B C   1 
ATOM 4488 O O   . MET D 4 154 ? 278.696 363.601 453.175 1.00 82.62  ? 154 MET B O   1 
ATOM 4489 C CB  . MET D 4 154 ? 281.058 365.597 452.903 1.00 82.62  ? 154 MET B CB  1 
ATOM 4490 C CG  . MET D 4 154 ? 281.746 366.797 452.328 1.00 82.62  ? 154 MET B CG  1 
ATOM 4491 S SD  . MET D 4 154 ? 282.510 367.812 453.596 1.00 82.62  ? 154 MET B SD  1 
ATOM 4492 C CE  . MET D 4 154 ? 283.138 369.156 452.599 1.00 82.62  ? 154 MET B CE  1 
ATOM 4493 N N   . PHE D 4 155 ? 280.484 362.405 452.520 1.00 80.81  ? 155 PHE B N   1 
ATOM 4494 C CA  . PHE D 4 155 ? 280.190 361.309 453.421 1.00 80.81  ? 155 PHE B CA  1 
ATOM 4495 C C   . PHE D 4 155 ? 280.691 361.650 454.817 1.00 80.81  ? 155 PHE B C   1 
ATOM 4496 O O   . PHE D 4 155 ? 281.421 362.618 455.025 1.00 80.81  ? 155 PHE B O   1 
ATOM 4497 C CB  . PHE D 4 155 ? 280.851 360.016 452.961 1.00 80.81  ? 155 PHE B CB  1 
ATOM 4498 C CG  . PHE D 4 155 ? 280.287 359.451 451.701 1.00 80.81  ? 155 PHE B CG  1 
ATOM 4499 C CD1 . PHE D 4 155 ? 278.973 359.064 451.630 1.00 80.81  ? 155 PHE B CD1 1 
ATOM 4500 C CD2 . PHE D 4 155 ? 281.092 359.265 450.598 1.00 80.81  ? 155 PHE B CD2 1 
ATOM 4501 C CE1 . PHE D 4 155 ? 278.464 358.530 450.473 1.00 80.81  ? 155 PHE B CE1 1 
ATOM 4502 C CE2 . PHE D 4 155 ? 280.587 358.730 449.445 1.00 80.81  ? 155 PHE B CE2 1 
ATOM 4503 C CZ  . PHE D 4 155 ? 279.274 358.364 449.383 1.00 80.81  ? 155 PHE B CZ  1 
ATOM 4504 N N   . THR D 4 156 ? 280.299 360.837 455.785 1.00 90.38  ? 156 THR B N   1 
ATOM 4505 C CA  . THR D 4 156 ? 280.842 360.925 457.128 1.00 90.38  ? 156 THR B CA  1 
ATOM 4506 C C   . THR D 4 156 ? 281.465 359.590 457.489 1.00 90.38  ? 156 THR B C   1 
ATOM 4507 O O   . THR D 4 156 ? 281.242 358.578 456.825 1.00 90.38  ? 156 THR B O   1 
ATOM 4508 C CB  . THR D 4 156 ? 279.781 361.279 458.169 1.00 90.38  ? 156 THR B CB  1 
ATOM 4509 O OG1 . THR D 4 156 ? 278.850 360.200 458.281 1.00 90.38  ? 156 THR B OG1 1 
ATOM 4510 C CG2 . THR D 4 156 ? 279.042 362.541 457.789 1.00 90.38  ? 156 THR B CG2 1 
ATOM 4511 N N   . ASP D 4 157 ? 282.255 359.594 458.552 1.00 95.32  ? 157 ASP B N   1 
ATOM 4512 C CA  . ASP D 4 157 ? 282.842 358.372 459.068 1.00 95.32  ? 157 ASP B CA  1 
ATOM 4513 C C   . ASP D 4 157 ? 282.120 357.853 460.304 1.00 95.32  ? 157 ASP B C   1 
ATOM 4514 O O   . ASP D 4 157 ? 282.504 356.813 460.841 1.00 95.32  ? 157 ASP B O   1 
ATOM 4515 C CB  . ASP D 4 157 ? 284.328 358.587 459.350 1.00 95.32  ? 157 ASP B CB  1 
ATOM 4516 C CG  . ASP D 4 157 ? 284.592 359.797 460.216 1.00 95.32  ? 157 ASP B CG  1 
ATOM 4517 O OD1 . ASP D 4 157 ? 283.635 360.522 460.547 1.00 95.32  ? 157 ASP B OD1 1 
ATOM 4518 O OD2 . ASP D 4 157 ? 285.768 360.033 460.558 1.00 95.32  ? 157 ASP B OD2 1 
ATOM 4519 N N   . THR D 4 158 ? 281.096 358.557 460.766 1.00 93.91  ? 158 THR B N   1 
ATOM 4520 C CA  . THR D 4 158 ? 280.213 358.088 461.824 1.00 93.91  ? 158 THR B CA  1 
ATOM 4521 C C   . THR D 4 158 ? 278.813 357.915 461.245 1.00 93.91  ? 158 THR B C   1 
ATOM 4522 O O   . THR D 4 158 ? 278.550 358.265 460.095 1.00 93.91  ? 158 THR B O   1 
ATOM 4523 C CB  . THR D 4 158 ? 280.198 359.060 462.999 1.00 93.91  ? 158 THR B CB  1 
ATOM 4524 O OG1 . THR D 4 158 ? 279.434 360.211 462.642 1.00 93.91  ? 158 THR B OG1 1 
ATOM 4525 C CG2 . THR D 4 158 ? 281.594 359.505 463.335 1.00 93.91  ? 158 THR B CG2 1 
ATOM 4526 N N   . GLN D 4 159 ? 277.904 357.385 462.052 1.00 94.23  ? 159 GLN B N   1 
ATOM 4527 C CA  . GLN D 4 159 ? 276.529 357.208 461.623 1.00 94.23  ? 159 GLN B CA  1 
ATOM 4528 C C   . GLN D 4 159 ? 275.807 358.543 461.600 1.00 94.23  ? 159 GLN B C   1 
ATOM 4529 O O   . GLN D 4 159 ? 276.229 359.508 462.237 1.00 94.23  ? 159 GLN B O   1 
ATOM 4530 C CB  . GLN D 4 159 ? 275.782 356.263 462.555 1.00 94.23  ? 159 GLN B CB  1 
ATOM 4531 C CG  . GLN D 4 159 ? 276.264 354.847 462.529 1.00 94.23  ? 159 GLN B CG  1 
ATOM 4532 C CD  . GLN D 4 159 ? 275.311 353.922 463.236 1.00 94.23  ? 159 GLN B CD  1 
ATOM 4533 O OE1 . GLN D 4 159 ? 275.702 352.860 463.713 1.00 94.23  ? 159 GLN B OE1 1 
ATOM 4534 N NE2 . GLN D 4 159 ? 274.050 354.320 463.313 1.00 94.23  ? 159 GLN B NE2 1 
ATOM 4535 N N   . VAL D 4 160 ? 274.707 358.588 460.862 1.00 97.34  ? 160 VAL B N   1 
ATOM 4536 C CA  . VAL D 4 160 ? 273.772 359.702 460.913 1.00 97.34  ? 160 VAL B CA  1 
ATOM 4537 C C   . VAL D 4 160 ? 272.649 359.293 461.847 1.00 97.34  ? 160 VAL B C   1 
ATOM 4538 O O   . VAL D 4 160 ? 272.277 358.116 461.892 1.00 97.34  ? 160 VAL B O   1 
ATOM 4539 C CB  . VAL D 4 160 ? 273.242 360.051 459.514 1.00 97.34  ? 160 VAL B CB  1 
ATOM 4540 C CG1 . VAL D 4 160 ? 272.542 361.387 459.519 1.00 97.34  ? 160 VAL B CG1 1 
ATOM 4541 C CG2 . VAL D 4 160 ? 274.379 360.077 458.537 1.00 97.34  ? 160 VAL B CG2 1 
ATOM 4542 N N   . GLY D 4 161 ? 272.135 360.249 462.614 1.00 104.69 ? 161 GLY B N   1 
ATOM 4543 C CA  . GLY D 4 161 ? 271.145 359.930 463.622 1.00 104.69 ? 161 GLY B CA  1 
ATOM 4544 C C   . GLY D 4 161 ? 269.826 359.483 463.025 1.00 104.69 ? 161 GLY B C   1 
ATOM 4545 O O   . GLY D 4 161 ? 269.561 359.644 461.837 1.00 104.69 ? 161 GLY B O   1 
ATOM 4546 N N   . GLU D 4 162 ? 269.004 358.871 463.866 1.00 114.02 ? 162 GLU B N   1 
ATOM 4547 C CA  . GLU D 4 162 ? 267.678 358.444 463.452 1.00 114.02 ? 162 GLU B CA  1 
ATOM 4548 C C   . GLU D 4 162 ? 266.639 359.528 463.683 1.00 114.02 ? 162 GLU B C   1 
ATOM 4549 O O   . GLU D 4 162 ? 265.644 359.593 462.956 1.00 114.02 ? 162 GLU B O   1 
ATOM 4550 C CB  . GLU D 4 162 ? 267.312 357.162 464.206 1.00 114.02 ? 162 GLU B CB  1 
ATOM 4551 C CG  . GLU D 4 162 ? 266.339 356.218 463.512 1.00 114.02 ? 162 GLU B CG  1 
ATOM 4552 C CD  . GLU D 4 162 ? 264.896 356.664 463.584 1.00 114.02 ? 162 GLU B CD  1 
ATOM 4553 O OE1 . GLU D 4 162 ? 264.102 356.235 462.724 1.00 114.02 ? 162 GLU B OE1 1 
ATOM 4554 O OE2 . GLU D 4 162 ? 264.545 357.414 464.519 1.00 114.02 ? 162 GLU B OE2 1 
ATOM 4555 N N   . SER D 4 163 ? 266.874 360.409 464.648 1.00 117.76 ? 163 SER B N   1 
ATOM 4556 C CA  . SER D 4 163 ? 265.873 361.363 465.101 1.00 117.76 ? 163 SER B CA  1 
ATOM 4557 C C   . SER D 4 163 ? 265.632 362.498 464.126 1.00 117.76 ? 163 SER B C   1 
ATOM 4558 O O   . SER D 4 163 ? 264.583 363.142 464.211 1.00 117.76 ? 163 SER B O   1 
ATOM 4559 C CB  . SER D 4 163 ? 266.283 361.948 466.451 1.00 117.76 ? 163 SER B CB  1 
ATOM 4560 O OG  . SER D 4 163 ? 267.107 363.084 466.263 1.00 117.76 ? 163 SER B OG  1 
ATOM 4561 N N   . ASN D 4 164 ? 266.559 362.775 463.214 1.00 113.30 ? 164 ASN B N   1 
ATOM 4562 C CA  . ASN D 4 164 ? 266.323 363.851 462.267 1.00 113.30 ? 164 ASN B CA  1 
ATOM 4563 C C   . ASN D 4 164 ? 265.396 363.361 461.160 1.00 113.30 ? 164 ASN B C   1 
ATOM 4564 O O   . ASN D 4 164 ? 265.332 362.171 460.845 1.00 113.30 ? 164 ASN B O   1 
ATOM 4565 C CB  . ASN D 4 164 ? 267.642 364.384 461.719 1.00 113.30 ? 164 ASN B CB  1 
ATOM 4566 C CG  . ASN D 4 164 ? 268.492 363.309 461.116 1.00 113.30 ? 164 ASN B CG  1 
ATOM 4567 O OD1 . ASN D 4 164 ? 268.226 362.126 461.292 1.00 113.30 ? 164 ASN B OD1 1 
ATOM 4568 N ND2 . ASN D 4 164 ? 269.533 363.712 460.405 1.00 113.30 ? 164 ASN B ND2 1 
ATOM 4569 N N   . ALA D 4 165 ? 264.650 364.303 460.590 1.00 111.39 ? 165 ALA B N   1 
ATOM 4570 C CA  . ALA D 4 165 ? 263.525 364.002 459.716 1.00 111.39 ? 165 ALA B CA  1 
ATOM 4571 C C   . ALA D 4 165 ? 263.927 363.318 458.421 1.00 111.39 ? 165 ALA B C   1 
ATOM 4572 O O   . ALA D 4 165 ? 263.567 362.162 458.188 1.00 111.39 ? 165 ALA B O   1 
ATOM 4573 C CB  . ALA D 4 165 ? 262.758 365.286 459.396 1.00 111.39 ? 165 ALA B CB  1 
ATOM 4574 N N   . LYS D 4 166 ? 264.687 364.010 457.579 1.00 107.72 ? 166 LYS B N   1 
ATOM 4575 C CA  . LYS D 4 166 ? 264.900 363.532 456.220 1.00 107.72 ? 166 LYS B CA  1 
ATOM 4576 C C   . LYS D 4 166 ? 266.299 363.934 455.786 1.00 107.72 ? 166 LYS B C   1 
ATOM 4577 O O   . LYS D 4 166 ? 266.489 365.032 455.259 1.00 107.72 ? 166 LYS B O   1 
ATOM 4578 C CB  . LYS D 4 166 ? 263.850 364.114 455.288 1.00 107.72 ? 166 LYS B CB  1 
ATOM 4579 C CG  . LYS D 4 166 ? 262.593 363.280 455.189 1.00 107.72 ? 166 LYS B CG  1 
ATOM 4580 C CD  . LYS D 4 166 ? 261.386 364.124 454.842 1.00 107.72 ? 166 LYS B CD  1 
ATOM 4581 C CE  . LYS D 4 166 ? 261.591 364.856 453.535 1.00 107.72 ? 166 LYS B CE  1 
ATOM 4582 N NZ  . LYS D 4 166 ? 260.356 365.556 453.104 1.00 107.72 ? 166 LYS B NZ  1 
ATOM 4583 N N   . LYS D 4 167 ? 267.263 363.046 455.991 1.00 103.94 ? 167 LYS B N   1 
ATOM 4584 C CA  . LYS D 4 167 ? 268.636 363.288 455.587 1.00 103.94 ? 167 LYS B CA  1 
ATOM 4585 C C   . LYS D 4 167 ? 269.239 361.975 455.122 1.00 103.94 ? 167 LYS B C   1 
ATOM 4586 O O   . LYS D 4 167 ? 268.805 360.893 455.519 1.00 103.94 ? 167 LYS B O   1 
ATOM 4587 C CB  . LYS D 4 167 ? 269.458 363.895 456.725 1.00 103.94 ? 167 LYS B CB  1 
ATOM 4588 C CG  . LYS D 4 167 ? 269.404 365.406 456.765 1.00 103.94 ? 167 LYS B CG  1 
ATOM 4589 C CD  . LYS D 4 167 ? 270.200 365.963 457.923 1.00 103.94 ? 167 LYS B CD  1 
ATOM 4590 C CE  . LYS D 4 167 ? 271.669 365.623 457.788 1.00 103.94 ? 167 LYS B CE  1 
ATOM 4591 N NZ  . LYS D 4 167 ? 272.440 366.058 458.985 1.00 103.94 ? 167 LYS B NZ  1 
ATOM 4592 N N   . VAL D 4 168 ? 270.244 362.079 454.273 1.00 97.78  ? 168 VAL B N   1 
ATOM 4593 C CA  . VAL D 4 168 ? 270.826 360.921 453.613 1.00 97.78  ? 168 VAL B CA  1 
ATOM 4594 C C   . VAL D 4 168 ? 271.702 360.185 454.611 1.00 97.78  ? 168 VAL B C   1 
ATOM 4595 O O   . VAL D 4 168 ? 272.495 360.806 455.322 1.00 97.78  ? 168 VAL B O   1 
ATOM 4596 C CB  . VAL D 4 168 ? 271.632 361.355 452.383 1.00 97.78  ? 168 VAL B CB  1 
ATOM 4597 C CG1 . VAL D 4 168 ? 272.240 360.163 451.685 1.00 97.78  ? 168 VAL B CG1 1 
ATOM 4598 C CG2 . VAL D 4 168 ? 270.753 362.127 451.446 1.00 97.78  ? 168 VAL B CG2 1 
ATOM 4599 N N   . GLN D 4 169 ? 271.547 358.869 454.682 1.00 93.66  ? 169 GLN B N   1 
ATOM 4600 C CA  . GLN D 4 169 ? 272.401 358.045 455.531 1.00 93.66  ? 169 GLN B CA  1 
ATOM 4601 C C   . GLN D 4 169 ? 273.769 357.946 454.880 1.00 93.66  ? 169 GLN B C   1 
ATOM 4602 O O   . GLN D 4 169 ? 273.926 357.327 453.829 1.00 93.66  ? 169 GLN B O   1 
ATOM 4603 C CB  . GLN D 4 169 ? 271.788 356.668 455.725 1.00 93.66  ? 169 GLN B CB  1 
ATOM 4604 C CG  . GLN D 4 169 ? 272.639 355.749 456.541 1.00 93.66  ? 169 GLN B CG  1 
ATOM 4605 C CD  . GLN D 4 169 ? 272.590 356.084 457.998 1.00 93.66  ? 169 GLN B CD  1 
ATOM 4606 O OE1 . GLN D 4 169 ? 273.422 356.827 458.502 1.00 93.66  ? 169 GLN B OE1 1 
ATOM 4607 N NE2 . GLN D 4 169 ? 271.609 355.539 458.694 1.00 93.66  ? 169 GLN B NE2 1 
ATOM 4608 N N   . THR D 4 170 ? 274.773 358.550 455.501 1.00 92.57  ? 170 THR B N   1 
ATOM 4609 C CA  . THR D 4 170 ? 276.093 358.682 454.905 1.00 92.57  ? 170 THR B CA  1 
ATOM 4610 C C   . THR D 4 170 ? 277.161 357.975 455.724 1.00 92.57  ? 170 THR B C   1 
ATOM 4611 O O   . THR D 4 170 ? 278.208 358.547 456.027 1.00 92.57  ? 170 THR B O   1 
ATOM 4612 C CB  . THR D 4 170 ? 276.469 360.146 454.732 1.00 92.57  ? 170 THR B CB  1 
ATOM 4613 O OG1 . THR D 4 170 ? 276.506 360.772 456.017 1.00 92.57  ? 170 THR B OG1 1 
ATOM 4614 C CG2 . THR D 4 170 ? 275.476 360.855 453.853 1.00 92.57  ? 170 THR B CG2 1 
ATOM 4615 N N   . ALA D 4 171 ? 276.912 356.731 456.115 1.00 90.71  ? 171 ALA B N   1 
ATOM 4616 C CA  . ALA D 4 171 ? 277.988 355.902 456.636 1.00 90.71  ? 171 ALA B CA  1 
ATOM 4617 C C   . ALA D 4 171 ? 278.818 355.396 455.470 1.00 90.71  ? 171 ALA B C   1 
ATOM 4618 O O   . ALA D 4 171 ? 278.296 354.734 454.572 1.00 90.71  ? 171 ALA B O   1 
ATOM 4619 C CB  . ALA D 4 171 ? 277.426 354.737 457.442 1.00 90.71  ? 171 ALA B CB  1 
ATOM 4620 N N   . VAL D 4 172 ? 280.114 355.709 455.479 1.00 83.89  ? 172 VAL B N   1 
ATOM 4621 C CA  . VAL D 4 172 ? 280.906 355.533 454.269 1.00 83.89  ? 172 VAL B CA  1 
ATOM 4622 C C   . VAL D 4 172 ? 281.257 354.068 454.042 1.00 83.89  ? 172 VAL B C   1 
ATOM 4623 O O   . VAL D 4 172 ? 281.485 353.652 452.903 1.00 83.89  ? 172 VAL B O   1 
ATOM 4624 C CB  . VAL D 4 172 ? 282.150 356.438 454.327 1.00 83.89  ? 172 VAL B CB  1 
ATOM 4625 C CG1 . VAL D 4 172 ? 283.149 355.936 455.340 1.00 83.89  ? 172 VAL B CG1 1 
ATOM 4626 C CG2 . VAL D 4 172 ? 282.784 356.596 452.962 1.00 83.89  ? 172 VAL B CG2 1 
ATOM 4627 N N   . TRP D 4 173 ? 281.242 353.242 455.086 1.00 85.94  ? 173 TRP B N   1 
ATOM 4628 C CA  . TRP D 4 173 ? 281.541 351.833 454.872 1.00 85.94  ? 173 TRP B CA  1 
ATOM 4629 C C   . TRP D 4 173 ? 280.373 351.065 454.280 1.00 85.94  ? 173 TRP B C   1 
ATOM 4630 O O   . TRP D 4 173 ? 280.529 349.884 453.967 1.00 85.94  ? 173 TRP B O   1 
ATOM 4631 C CB  . TRP D 4 173 ? 281.980 351.167 456.171 1.00 85.94  ? 173 TRP B CB  1 
ATOM 4632 C CG  . TRP D 4 173 ? 280.974 351.218 457.237 1.00 85.94  ? 173 TRP B CG  1 
ATOM 4633 C CD1 . TRP D 4 173 ? 280.020 350.294 457.501 1.00 85.94  ? 173 TRP B CD1 1 
ATOM 4634 C CD2 . TRP D 4 173 ? 280.819 352.247 458.205 1.00 85.94  ? 173 TRP B CD2 1 
ATOM 4635 N NE1 . TRP D 4 173 ? 279.268 350.684 458.575 1.00 85.94  ? 173 TRP B NE1 1 
ATOM 4636 C CE2 . TRP D 4 173 ? 279.741 351.886 459.025 1.00 85.94  ? 173 TRP B CE2 1 
ATOM 4637 C CE3 . TRP D 4 173 ? 281.483 353.445 458.456 1.00 85.94  ? 173 TRP B CE3 1 
ATOM 4638 C CZ2 . TRP D 4 173 ? 279.313 352.675 460.075 1.00 85.94  ? 173 TRP B CZ2 1 
ATOM 4639 C CZ3 . TRP D 4 173 ? 281.060 354.226 459.499 1.00 85.94  ? 173 TRP B CZ3 1 
ATOM 4640 C CH2 . TRP D 4 173 ? 279.985 353.841 460.297 1.00 85.94  ? 173 TRP B CH2 1 
ATOM 4641 N N   . ASN D 4 174 ? 279.209 351.692 454.136 1.00 86.55  ? 174 ASN B N   1 
ATOM 4642 C CA  . ASN D 4 174 ? 278.109 351.122 453.382 1.00 86.55  ? 174 ASN B CA  1 
ATOM 4643 C C   . ASN D 4 174 ? 277.788 351.912 452.128 1.00 86.55  ? 174 ASN B C   1 
ATOM 4644 O O   . ASN D 4 174 ? 276.850 351.551 451.415 1.00 86.55  ? 174 ASN B O   1 
ATOM 4645 C CB  . ASN D 4 174 ? 276.862 351.010 454.251 1.00 86.55  ? 174 ASN B CB  1 
ATOM 4646 C CG  . ASN D 4 174 ? 276.950 349.874 455.220 1.00 86.55  ? 174 ASN B CG  1 
ATOM 4647 O OD1 . ASN D 4 174 ? 276.820 350.057 456.425 1.00 86.55  ? 174 ASN B OD1 1 
ATOM 4648 N ND2 . ASN D 4 174 ? 277.199 348.683 454.704 1.00 86.55  ? 174 ASN B ND2 1 
ATOM 4649 N N   . ALA D 4 175 ? 278.523 352.991 451.866 1.00 85.04  ? 175 ALA B N   1 
ATOM 4650 C CA  . ALA D 4 175 ? 278.451 353.827 450.671 1.00 85.04  ? 175 ALA B CA  1 
ATOM 4651 C C   . ALA D 4 175 ? 277.086 354.455 450.443 1.00 85.04  ? 175 ALA B C   1 
ATOM 4652 O O   . ALA D 4 175 ? 276.769 354.828 449.314 1.00 85.04  ? 175 ALA B O   1 
ATOM 4653 C CB  . ALA D 4 175 ? 278.874 353.060 449.414 1.00 85.04  ? 175 ALA B CB  1 
ATOM 4654 N N   . GLY D 4 176 ? 276.257 354.571 451.475 1.00 90.56  ? 176 GLY B N   1 
ATOM 4655 C CA  . GLY D 4 176 ? 274.966 355.210 451.349 1.00 90.56  ? 176 GLY B CA  1 
ATOM 4656 C C   . GLY D 4 176 ? 273.906 354.430 450.602 1.00 90.56  ? 176 GLY B C   1 
ATOM 4657 O O   . GLY D 4 176 ? 272.763 354.886 450.540 1.00 90.56  ? 176 GLY B O   1 
ATOM 4658 N N   . MET D 4 177 ? 274.234 353.268 450.037 1.00 91.35  ? 177 MET B N   1 
ATOM 4659 C CA  . MET D 4 177 ? 273.284 352.485 449.261 1.00 91.35  ? 177 MET B CA  1 
ATOM 4660 C C   . MET D 4 177 ? 272.995 351.145 449.914 1.00 91.35  ? 177 MET B C   1 
ATOM 4661 O O   . MET D 4 177 ? 272.322 350.303 449.316 1.00 91.35  ? 177 MET B O   1 
ATOM 4662 C CB  . MET D 4 177 ? 273.804 352.263 447.842 1.00 91.35  ? 177 MET B CB  1 
ATOM 4663 C CG  . MET D 4 177 ? 274.306 353.507 447.166 1.00 91.35  ? 177 MET B CG  1 
ATOM 4664 S SD  . MET D 4 177 ? 274.774 353.183 445.466 1.00 91.35  ? 177 MET B SD  1 
ATOM 4665 C CE  . MET D 4 177 ? 276.093 352.012 445.718 1.00 91.35  ? 177 MET B CE  1 
ATOM 4666 N N   . GLY D 4 178 ? 273.494 350.926 451.124 1.00 86.16  ? 178 GLY B N   1 
ATOM 4667 C CA  . GLY D 4 178 ? 273.309 349.652 451.779 1.00 86.16  ? 178 GLY B CA  1 
ATOM 4668 C C   . GLY D 4 178 ? 274.070 348.514 451.154 1.00 86.16  ? 178 GLY B C   1 
ATOM 4669 O O   . GLY D 4 178 ? 273.602 347.379 451.186 1.00 86.16  ? 178 GLY B O   1 
ATOM 4670 N N   . VAL D 4 179 ? 275.234 348.783 450.582 1.00 84.64  ? 179 VAL B N   1 
ATOM 4671 C CA  . VAL D 4 179 ? 276.016 347.775 449.887 1.00 84.64  ? 179 VAL B CA  1 
ATOM 4672 C C   . VAL D 4 179 ? 277.401 347.766 450.514 1.00 84.64  ? 179 VAL B C   1 
ATOM 4673 O O   . VAL D 4 179 ? 277.761 348.682 451.254 1.00 84.64  ? 179 VAL B O   1 
ATOM 4674 C CB  . VAL D 4 179 ? 276.075 348.079 448.375 1.00 84.64  ? 179 VAL B CB  1 
ATOM 4675 C CG1 . VAL D 4 179 ? 277.118 349.135 448.058 1.00 84.64  ? 179 VAL B CG1 1 
ATOM 4676 C CG2 . VAL D 4 179 ? 276.258 346.840 447.572 1.00 84.64  ? 179 VAL B CG2 1 
ATOM 4677 N N   . GLY D 4 180 ? 278.169 346.712 450.254 1.00 82.90  ? 180 GLY B N   1 
ATOM 4678 C CA  . GLY D 4 180 ? 279.544 346.680 450.724 1.00 82.90  ? 180 GLY B CA  1 
ATOM 4679 C C   . GLY D 4 180 ? 280.378 347.695 449.970 1.00 82.90  ? 180 GLY B C   1 
ATOM 4680 O O   . GLY D 4 180 ? 280.235 347.850 448.754 1.00 82.90  ? 180 GLY B O   1 
ATOM 4681 N N   . VAL D 4 181 ? 281.240 348.414 450.691 1.00 77.45  ? 181 VAL B N   1 
ATOM 4682 C CA  . VAL D 4 181 ? 282.034 349.451 450.046 1.00 77.45  ? 181 VAL B CA  1 
ATOM 4683 C C   . VAL D 4 181 ? 283.191 348.836 449.271 1.00 77.45  ? 181 VAL B C   1 
ATOM 4684 O O   . VAL D 4 181 ? 283.687 349.434 448.311 1.00 77.45  ? 181 VAL B O   1 
ATOM 4685 C CB  . VAL D 4 181 ? 282.489 350.474 451.109 1.00 77.45  ? 181 VAL B CB  1 
ATOM 4686 C CG1 . VAL D 4 181 ? 283.343 349.820 452.154 1.00 77.45  ? 181 VAL B CG1 1 
ATOM 4687 C CG2 . VAL D 4 181 ? 283.183 351.683 450.501 1.00 77.45  ? 181 VAL B CG2 1 
ATOM 4688 N N   . GLY D 4 182 ? 283.596 347.619 449.619 1.00 79.04  ? 182 GLY B N   1 
ATOM 4689 C CA  . GLY D 4 182 ? 284.679 346.985 448.897 1.00 79.04  ? 182 GLY B CA  1 
ATOM 4690 C C   . GLY D 4 182 ? 284.278 346.492 447.527 1.00 79.04  ? 182 GLY B C   1 
ATOM 4691 O O   . GLY D 4 182 ? 285.095 346.483 446.607 1.00 79.04  ? 182 GLY B O   1 
ATOM 4692 N N   . ASN D 4 183 ? 283.019 346.106 447.357 1.00 78.55  ? 183 ASN B N   1 
ATOM 4693 C CA  . ASN D 4 183 ? 282.547 345.564 446.096 1.00 78.55  ? 183 ASN B CA  1 
ATOM 4694 C C   . ASN D 4 183 ? 282.145 346.634 445.101 1.00 78.55  ? 183 ASN B C   1 
ATOM 4695 O O   . ASN D 4 183 ? 281.519 346.313 444.092 1.00 78.55  ? 183 ASN B O   1 
ATOM 4696 C CB  . ASN D 4 183 ? 281.361 344.638 446.329 1.00 78.55  ? 183 ASN B CB  1 
ATOM 4697 C CG  . ASN D 4 183 ? 281.571 343.724 447.493 1.00 78.55  ? 183 ASN B CG  1 
ATOM 4698 O OD1 . ASN D 4 183 ? 282.701 343.391 447.828 1.00 78.55  ? 183 ASN B OD1 1 
ATOM 4699 N ND2 . ASN D 4 183 ? 280.484 343.314 448.128 1.00 78.55  ? 183 ASN B ND2 1 
ATOM 4700 N N   . LEU D 4 184 ? 282.495 347.889 445.340 1.00 72.40  ? 184 LEU B N   1 
ATOM 4701 C CA  . LEU D 4 184 ? 282.111 348.965 444.441 1.00 72.40  ? 184 LEU B CA  1 
ATOM 4702 C C   . LEU D 4 184 ? 282.944 349.019 443.178 1.00 72.40  ? 184 LEU B C   1 
ATOM 4703 O O   . LEU D 4 184 ? 282.715 349.904 442.354 1.00 72.40  ? 184 LEU B O   1 
ATOM 4704 C CB  . LEU D 4 184 ? 282.202 350.309 445.155 1.00 72.40  ? 184 LEU B CB  1 
ATOM 4705 C CG  . LEU D 4 184 ? 280.891 350.796 445.741 1.00 72.40  ? 184 LEU B CG  1 
ATOM 4706 C CD1 . LEU D 4 184 ? 281.105 352.078 446.495 1.00 72.40  ? 184 LEU B CD1 1 
ATOM 4707 C CD2 . LEU D 4 184 ? 279.916 351.003 444.625 1.00 72.40  ? 184 LEU B CD2 1 
ATOM 4708 N N   . THR D 4 185 ? 283.895 348.114 442.997 1.00 74.06  ? 185 THR B N   1 
ATOM 4709 C CA  . THR D 4 185 ? 284.760 348.138 441.832 1.00 74.06  ? 185 THR B CA  1 
ATOM 4710 C C   . THR D 4 185 ? 284.153 347.448 440.625 1.00 74.06  ? 185 THR B C   1 
ATOM 4711 O O   . THR D 4 185 ? 284.815 347.355 439.590 1.00 74.06  ? 185 THR B O   1 
ATOM 4712 C CB  . THR D 4 185 ? 286.096 347.484 442.151 1.00 74.06  ? 185 THR B CB  1 
ATOM 4713 O OG1 . THR D 4 185 ? 285.962 346.074 441.992 1.00 74.06  ? 185 THR B OG1 1 
ATOM 4714 C CG2 . THR D 4 185 ? 286.497 347.774 443.571 1.00 74.06  ? 185 THR B CG2 1 
ATOM 4715 N N   . ILE D 4 186 ? 282.924 346.949 440.729 1.00 75.67  ? 186 ILE B N   1 
ATOM 4716 C CA  . ILE D 4 186 ? 282.293 346.326 439.575 1.00 75.67  ? 186 ILE B CA  1 
ATOM 4717 C C   . ILE D 4 186 ? 281.833 347.386 438.576 1.00 75.67  ? 186 ILE B C   1 
ATOM 4718 O O   . ILE D 4 186 ? 281.843 347.154 437.364 1.00 75.67  ? 186 ILE B O   1 
ATOM 4719 C CB  . ILE D 4 186 ? 281.157 345.410 440.061 1.00 75.67  ? 186 ILE B CB  1 
ATOM 4720 C CG1 . ILE D 4 186 ? 280.408 344.759 438.906 1.00 75.67  ? 186 ILE B CG1 1 
ATOM 4721 C CG2 . ILE D 4 186 ? 280.221 346.159 440.934 1.00 75.67  ? 186 ILE B CG2 1 
ATOM 4722 C CD1 . ILE D 4 186 ? 279.280 343.880 439.352 1.00 75.67  ? 186 ILE B CD1 1 
ATOM 4723 N N   . PHE D 4 187 ? 281.497 348.579 439.055 1.00 75.41  ? 187 PHE B N   1 
ATOM 4724 C CA  . PHE D 4 187 ? 281.209 349.711 438.197 1.00 75.41  ? 187 PHE B CA  1 
ATOM 4725 C C   . PHE D 4 187 ? 282.501 350.193 437.536 1.00 75.41  ? 187 PHE B C   1 
ATOM 4726 O O   . PHE D 4 187 ? 283.591 349.841 437.988 1.00 75.41  ? 187 PHE B O   1 
ATOM 4727 C CB  . PHE D 4 187 ? 280.567 350.811 439.034 1.00 75.41  ? 187 PHE B CB  1 
ATOM 4728 C CG  . PHE D 4 187 ? 279.283 350.406 439.666 1.00 75.41  ? 187 PHE B CG  1 
ATOM 4729 C CD1 . PHE D 4 187 ? 278.225 349.986 438.891 1.00 75.41  ? 187 PHE B CD1 1 
ATOM 4730 C CD2 . PHE D 4 187 ? 279.127 350.454 441.033 1.00 75.41  ? 187 PHE B CD2 1 
ATOM 4731 C CE1 . PHE D 4 187 ? 277.044 349.619 439.469 1.00 75.41  ? 187 PHE B CE1 1 
ATOM 4732 C CE2 . PHE D 4 187 ? 277.946 350.085 441.614 1.00 75.41  ? 187 PHE B CE2 1 
ATOM 4733 C CZ  . PHE D 4 187 ? 276.905 349.671 440.831 1.00 75.41  ? 187 PHE B CZ  1 
ATOM 4734 N N   . PRO D 4 188 ? 282.415 350.955 436.440 1.00 75.81  ? 188 PRO B N   1 
ATOM 4735 C CA  . PRO D 4 188 ? 283.642 351.443 435.788 1.00 75.81  ? 188 PRO B CA  1 
ATOM 4736 C C   . PRO D 4 188 ? 284.422 352.400 436.674 1.00 75.81  ? 188 PRO B C   1 
ATOM 4737 O O   . PRO D 4 188 ? 283.966 353.496 436.989 1.00 75.81  ? 188 PRO B O   1 
ATOM 4738 C CB  . PRO D 4 188 ? 283.116 352.144 434.533 1.00 75.81  ? 188 PRO B CB  1 
ATOM 4739 C CG  . PRO D 4 188 ? 281.692 352.378 434.800 1.00 75.81  ? 188 PRO B CG  1 
ATOM 4740 C CD  . PRO D 4 188 ? 281.252 351.205 435.578 1.00 75.81  ? 188 PRO B CD  1 
ATOM 4741 N N   . HIS D 4 189 ? 285.614 351.971 437.068 1.00 74.83  ? 189 HIS B N   1 
ATOM 4742 C CA  . HIS D 4 189 ? 286.383 352.640 438.100 1.00 74.83  ? 189 HIS B CA  1 
ATOM 4743 C C   . HIS D 4 189 ? 287.813 352.815 437.628 1.00 74.83  ? 189 HIS B C   1 
ATOM 4744 O O   . HIS D 4 189 ? 288.199 352.339 436.559 1.00 74.83  ? 189 HIS B O   1 
ATOM 4745 C CB  . HIS D 4 189 ? 286.356 351.845 439.399 1.00 74.83  ? 189 HIS B CB  1 
ATOM 4746 C CG  . HIS D 4 189 ? 287.157 350.588 439.344 1.00 74.83  ? 189 HIS B CG  1 
ATOM 4747 N ND1 . HIS D 4 189 ? 286.965 349.625 438.378 1.00 74.83  ? 189 HIS B ND1 1 
ATOM 4748 C CD2 . HIS D 4 189 ? 288.150 350.130 440.137 1.00 74.83  ? 189 HIS B CD2 1 
ATOM 4749 C CE1 . HIS D 4 189 ? 287.808 348.629 438.577 1.00 74.83  ? 189 HIS B CE1 1 
ATOM 4750 N NE2 . HIS D 4 189 ? 288.538 348.910 439.639 1.00 74.83  ? 189 HIS B NE2 1 
ATOM 4751 N N   . GLN D 4 190 ? 288.608 353.490 438.453 1.00 77.41  ? 190 GLN B N   1 
ATOM 4752 C CA  . GLN D 4 190 ? 290.000 353.781 438.157 1.00 77.41  ? 190 GLN B CA  1 
ATOM 4753 C C   . GLN D 4 190 ? 290.676 354.180 439.456 1.00 77.41  ? 190 GLN B C   1 
ATOM 4754 O O   . GLN D 4 190 ? 290.144 355.002 440.197 1.00 77.41  ? 190 GLN B O   1 
ATOM 4755 C CB  . GLN D 4 190 ? 290.129 354.910 437.137 1.00 77.41  ? 190 GLN B CB  1 
ATOM 4756 C CG  . GLN D 4 190 ? 291.542 355.226 436.756 1.00 77.41  ? 190 GLN B CG  1 
ATOM 4757 C CD  . GLN D 4 190 ? 292.087 354.286 435.723 1.00 77.41  ? 190 GLN B CD  1 
ATOM 4758 O OE1 . GLN D 4 190 ? 292.687 353.267 436.051 1.00 77.41  ? 190 GLN B OE1 1 
ATOM 4759 N NE2 . GLN D 4 190 ? 291.913 354.637 434.460 1.00 77.41  ? 190 GLN B NE2 1 
ATOM 4760 N N   . TRP D 4 191 ? 291.838 353.605 439.729 1.00 74.19  ? 191 TRP B N   1 
ATOM 4761 C CA  . TRP D 4 191 ? 292.541 353.875 440.972 1.00 74.19  ? 191 TRP B CA  1 
ATOM 4762 C C   . TRP D 4 191 ? 293.482 355.056 440.816 1.00 74.19  ? 191 TRP B C   1 
ATOM 4763 O O   . TRP D 4 191 ? 294.177 355.182 439.807 1.00 74.19  ? 191 TRP B O   1 
ATOM 4764 C CB  . TRP D 4 191 ? 293.338 352.655 441.418 1.00 74.19  ? 191 TRP B CB  1 
ATOM 4765 C CG  . TRP D 4 191 ? 292.491 351.552 441.866 1.00 74.19  ? 191 TRP B CG  1 
ATOM 4766 C CD1 . TRP D 4 191 ? 292.058 350.508 441.122 1.00 74.19  ? 191 TRP B CD1 1 
ATOM 4767 C CD2 . TRP D 4 191 ? 291.954 351.369 443.171 1.00 74.19  ? 191 TRP B CD2 1 
ATOM 4768 N NE1 . TRP D 4 191 ? 291.278 349.678 441.881 1.00 74.19  ? 191 TRP B NE1 1 
ATOM 4769 C CE2 . TRP D 4 191 ? 291.200 350.190 443.147 1.00 74.19  ? 191 TRP B CE2 1 
ATOM 4770 C CE3 . TRP D 4 191 ? 292.038 352.087 444.359 1.00 74.19  ? 191 TRP B CE3 1 
ATOM 4771 C CZ2 . TRP D 4 191 ? 290.535 349.716 444.257 1.00 74.19  ? 191 TRP B CZ2 1 
ATOM 4772 C CZ3 . TRP D 4 191 ? 291.378 351.614 445.458 1.00 74.19  ? 191 TRP B CZ3 1 
ATOM 4773 C CH2 . TRP D 4 191 ? 290.639 350.440 445.401 1.00 74.19  ? 191 TRP B CH2 1 
ATOM 4774 N N   . ILE D 4 192 ? 293.516 355.910 441.826 1.00 76.87  ? 192 ILE B N   1 
ATOM 4775 C CA  . ILE D 4 192 ? 294.492 356.984 441.913 1.00 76.87  ? 192 ILE B CA  1 
ATOM 4776 C C   . ILE D 4 192 ? 295.366 356.663 443.112 1.00 76.87  ? 192 ILE B C   1 
ATOM 4777 O O   . ILE D 4 192 ? 294.925 356.756 444.261 1.00 76.87  ? 192 ILE B O   1 
ATOM 4778 C CB  . ILE D 4 192 ? 293.844 358.362 442.047 1.00 76.87  ? 192 ILE B CB  1 
ATOM 4779 C CG1 . ILE D 4 192 ? 293.124 358.724 440.758 1.00 76.87  ? 192 ILE B CG1 1 
ATOM 4780 C CG2 . ILE D 4 192 ? 294.890 359.408 442.342 1.00 76.87  ? 192 ILE B CG2 1 
ATOM 4781 C CD1 . ILE D 4 192 ? 292.501 360.079 440.788 1.00 76.87  ? 192 ILE B CD1 1 
ATOM 4782 N N   . ASN D 4 193 ? 296.597 356.256 442.848 1.00 83.55  ? 193 ASN B N   1 
ATOM 4783 C CA  . ASN D 4 193 ? 297.557 355.911 443.883 1.00 83.55  ? 193 ASN B CA  1 
ATOM 4784 C C   . ASN D 4 193 ? 298.674 356.938 443.836 1.00 83.55  ? 193 ASN B C   1 
ATOM 4785 O O   . ASN D 4 193 ? 299.368 357.046 442.825 1.00 83.55  ? 193 ASN B O   1 
ATOM 4786 C CB  . ASN D 4 193 ? 298.099 354.504 443.665 1.00 83.55  ? 193 ASN B CB  1 
ATOM 4787 C CG  . ASN D 4 193 ? 299.007 354.058 444.770 1.00 83.55  ? 193 ASN B CG  1 
ATOM 4788 O OD1 . ASN D 4 193 ? 298.976 354.600 445.869 1.00 83.55  ? 193 ASN B OD1 1 
ATOM 4789 N ND2 . ASN D 4 193 ? 299.822 353.053 444.494 1.00 83.55  ? 193 ASN B ND2 1 
ATOM 4790 N N   . LEU D 4 194 ? 298.860 357.671 444.934 1.00 83.43  ? 194 LEU B N   1 
ATOM 4791 C CA  . LEU D 4 194 ? 299.784 358.799 444.943 1.00 83.43  ? 194 LEU B CA  1 
ATOM 4792 C C   . LEU D 4 194 ? 301.246 358.392 444.877 1.00 83.43  ? 194 LEU B C   1 
ATOM 4793 O O   . LEU D 4 194 ? 302.102 359.264 444.707 1.00 83.43  ? 194 LEU B O   1 
ATOM 4794 C CB  . LEU D 4 194 ? 299.554 359.651 446.183 1.00 83.43  ? 194 LEU B CB  1 
ATOM 4795 C CG  . LEU D 4 194 ? 298.418 360.651 446.050 1.00 83.43  ? 194 LEU B CG  1 
ATOM 4796 C CD1 . LEU D 4 194 ? 298.283 361.440 447.317 1.00 83.43  ? 194 LEU B CD1 1 
ATOM 4797 C CD2 . LEU D 4 194 ? 298.713 361.567 444.904 1.00 83.43  ? 194 LEU B CD2 1 
ATOM 4798 N N   . ARG D 4 195 ? 301.555 357.108 445.018 1.00 86.16  ? 195 ARG B N   1 
ATOM 4799 C CA  . ARG D 4 195 ? 302.927 356.659 444.834 1.00 86.16  ? 195 ARG B CA  1 
ATOM 4800 C C   . ARG D 4 195 ? 303.328 356.702 443.367 1.00 86.16  ? 195 ARG B C   1 
ATOM 4801 O O   . ARG D 4 195 ? 304.414 357.182 443.031 1.00 86.16  ? 195 ARG B O   1 
ATOM 4802 C CB  . ARG D 4 195 ? 303.080 355.251 445.392 1.00 86.16  ? 195 ARG B CB  1 
ATOM 4803 C CG  . ARG D 4 195 ? 304.427 354.638 445.161 1.00 86.16  ? 195 ARG B CG  1 
ATOM 4804 C CD  . ARG D 4 195 ? 304.394 353.168 445.477 1.00 86.16  ? 195 ARG B CD  1 
ATOM 4805 N NE  . ARG D 4 195 ? 305.716 352.579 445.366 1.00 86.16  ? 195 ARG B NE  1 
ATOM 4806 C CZ  . ARG D 4 195 ? 306.579 352.520 446.368 1.00 86.16  ? 195 ARG B CZ  1 
ATOM 4807 N NH1 . ARG D 4 195 ? 306.249 353.012 447.550 1.00 86.16  ? 195 ARG B NH1 1 
ATOM 4808 N NH2 . ARG D 4 195 ? 307.767 351.968 446.188 1.00 86.16  ? 195 ARG B NH2 1 
ATOM 4809 N N   . THR D 4 196 ? 302.466 356.226 442.480 1.00 88.48  ? 196 THR B N   1 
ATOM 4810 C CA  . THR D 4 196 ? 302.824 356.087 441.075 1.00 88.48  ? 196 THR B CA  1 
ATOM 4811 C C   . THR D 4 196 ? 301.905 356.820 440.112 1.00 88.48  ? 196 THR B C   1 
ATOM 4812 O O   . THR D 4 196 ? 302.349 357.211 439.034 1.00 88.48  ? 196 THR B O   1 
ATOM 4813 C CB  . THR D 4 196 ? 302.880 354.600 440.691 1.00 88.48  ? 196 THR B CB  1 
ATOM 4814 O OG1 . THR D 4 196 ? 303.202 354.480 439.302 1.00 88.48  ? 196 THR B OG1 1 
ATOM 4815 C CG2 . THR D 4 196 ? 301.569 353.887 440.982 1.00 88.48  ? 196 THR B CG2 1 
ATOM 4816 N N   . ASN D 4 197 ? 300.641 357.019 440.455 1.00 86.08  ? 197 ASN B N   1 
ATOM 4817 C CA  . ASN D 4 197 ? 299.682 357.640 439.558 1.00 86.08  ? 197 ASN B CA  1 
ATOM 4818 C C   . ASN D 4 197 ? 299.333 359.029 440.062 1.00 86.08  ? 197 ASN B C   1 
ATOM 4819 O O   . ASN D 4 197 ? 299.638 359.401 441.193 1.00 86.08  ? 197 ASN B O   1 
ATOM 4820 C CB  . ASN D 4 197 ? 298.425 356.782 439.436 1.00 86.08  ? 197 ASN B CB  1 
ATOM 4821 C CG  . ASN D 4 197 ? 297.821 356.846 438.067 1.00 86.08  ? 197 ASN B CG  1 
ATOM 4822 O OD1 . ASN D 4 197 ? 298.341 357.525 437.187 1.00 86.08  ? 197 ASN B OD1 1 
ATOM 4823 N ND2 . ASN D 4 197 ? 296.722 356.134 437.868 1.00 86.08  ? 197 ASN B ND2 1 
ATOM 4824 N N   . ASN D 4 198 ? 298.708 359.816 439.197 1.00 87.35  ? 198 ASN B N   1 
ATOM 4825 C CA  . ASN D 4 198 ? 298.294 361.140 439.633 1.00 87.35  ? 198 ASN B CA  1 
ATOM 4826 C C   . ASN D 4 198 ? 296.888 361.486 439.178 1.00 87.35  ? 198 ASN B C   1 
ATOM 4827 O O   . ASN D 4 198 ? 296.207 362.285 439.823 1.00 87.35  ? 198 ASN B O   1 
ATOM 4828 C CB  . ASN D 4 198 ? 299.277 362.188 439.126 1.00 87.35  ? 198 ASN B CB  1 
ATOM 4829 C CG  . ASN D 4 198 ? 299.085 363.515 439.793 1.00 87.35  ? 198 ASN B CG  1 
ATOM 4830 O OD1 . ASN D 4 198 ? 298.869 364.527 439.135 1.00 87.35  ? 198 ASN B OD1 1 
ATOM 4831 N ND2 . ASN D 4 198 ? 299.149 363.520 441.113 1.00 87.35  ? 198 ASN B ND2 1 
ATOM 4832 N N   . SER D 4 199 ? 296.436 360.894 438.078 1.00 86.34  ? 199 SER B N   1 
ATOM 4833 C CA  . SER D 4 199 ? 295.202 361.322 437.442 1.00 86.34  ? 199 SER B CA  1 
ATOM 4834 C C   . SER D 4 199 ? 294.379 360.116 437.022 1.00 86.34  ? 199 SER B C   1 
ATOM 4835 O O   . SER D 4 199 ? 294.873 358.993 436.940 1.00 86.34  ? 199 SER B O   1 
ATOM 4836 C CB  . SER D 4 199 ? 295.487 362.194 436.225 1.00 86.34  ? 199 SER B CB  1 
ATOM 4837 O OG  . SER D 4 199 ? 295.813 361.384 435.114 1.00 86.34  ? 199 SER B OG  1 
ATOM 4838 N N   . ALA D 4 200 ? 293.108 360.373 436.738 1.00 83.58  ? 200 ALA B N   1 
ATOM 4839 C CA  . ALA D 4 200 ? 292.175 359.357 436.285 1.00 83.58  ? 200 ALA B CA  1 
ATOM 4840 C C   . ALA D 4 200 ? 291.295 359.945 435.197 1.00 83.58  ? 200 ALA B C   1 
ATOM 4841 O O   . ALA D 4 200 ? 291.045 361.149 435.161 1.00 83.58  ? 200 ALA B O   1 
ATOM 4842 C CB  . ALA D 4 200 ? 291.306 358.844 437.428 1.00 83.58  ? 200 ALA B CB  1 
ATOM 4843 N N   . THR D 4 201 ? 290.825 359.084 434.301 1.00 86.06  ? 201 THR B N   1 
ATOM 4844 C CA  . THR D 4 201 ? 289.991 359.527 433.191 1.00 86.06  ? 201 THR B CA  1 
ATOM 4845 C C   . THR D 4 201 ? 288.922 358.484 432.930 1.00 86.06  ? 201 THR B C   1 
ATOM 4846 O O   . THR D 4 201 ? 289.234 357.299 432.800 1.00 86.06  ? 201 THR B O   1 
ATOM 4847 C CB  . THR D 4 201 ? 290.815 359.752 431.930 1.00 86.06  ? 201 THR B CB  1 
ATOM 4848 O OG1 . THR D 4 201 ? 292.000 360.489 432.251 1.00 86.06  ? 201 THR B OG1 1 
ATOM 4849 C CG2 . THR D 4 201 ? 290.011 360.526 430.912 1.00 86.06  ? 201 THR B CG2 1 
ATOM 4850 N N   . LEU D 4 202 ? 287.676 358.920 432.840 1.00 80.56  ? 202 LEU B N   1 
ATOM 4851 C CA  . LEU D 4 202 ? 286.543 358.044 432.598 1.00 80.56  ? 202 LEU B CA  1 
ATOM 4852 C C   . LEU D 4 202 ? 285.738 358.587 431.432 1.00 80.56  ? 202 LEU B C   1 
ATOM 4853 O O   . LEU D 4 202 ? 285.656 359.801 431.240 1.00 80.56  ? 202 LEU B O   1 
ATOM 4854 C CB  . LEU D 4 202 ? 285.658 357.953 433.829 1.00 80.56  ? 202 LEU B CB  1 
ATOM 4855 C CG  . LEU D 4 202 ? 286.267 357.325 435.071 1.00 80.56  ? 202 LEU B CG  1 
ATOM 4856 C CD1 . LEU D 4 202 ? 285.567 357.846 436.284 1.00 80.56  ? 202 LEU B CD1 1 
ATOM 4857 C CD2 . LEU D 4 202 ? 286.085 355.846 434.996 1.00 80.56  ? 202 LEU B CD2 1 
ATOM 4858 N N   . VAL D 4 203 ? 285.156 357.690 430.645 1.00 82.84  ? 203 VAL B N   1 
ATOM 4859 C CA  . VAL D 4 203 ? 284.243 358.058 429.573 1.00 82.84  ? 203 VAL B CA  1 
ATOM 4860 C C   . VAL D 4 203 ? 282.995 357.214 429.740 1.00 82.84  ? 203 VAL B C   1 
ATOM 4861 O O   . VAL D 4 203 ? 283.071 355.983 429.693 1.00 82.84  ? 203 VAL B O   1 
ATOM 4862 C CB  . VAL D 4 203 ? 284.852 357.836 428.184 1.00 82.84  ? 203 VAL B CB  1 
ATOM 4863 C CG1 . VAL D 4 203 ? 283.796 358.011 427.132 1.00 82.84  ? 203 VAL B CG1 1 
ATOM 4864 C CG2 . VAL D 4 203 ? 285.983 358.797 427.944 1.00 82.84  ? 203 VAL B CG2 1 
ATOM 4865 N N   . MET D 4 204 ? 281.852 357.859 429.934 1.00 87.93  ? 204 MET B N   1 
ATOM 4866 C CA  . MET D 4 204 ? 280.640 357.142 430.268 1.00 87.93  ? 204 MET B CA  1 
ATOM 4867 C C   . MET D 4 204 ? 279.564 357.363 429.216 1.00 87.93  ? 204 MET B C   1 
ATOM 4868 O O   . MET D 4 204 ? 279.244 358.515 428.895 1.00 87.93  ? 204 MET B O   1 
ATOM 4869 C CB  . MET D 4 204 ? 280.129 357.583 431.624 1.00 87.93  ? 204 MET B CB  1 
ATOM 4870 C CG  . MET D 4 204 ? 281.071 357.233 432.727 1.00 87.93  ? 204 MET B CG  1 
ATOM 4871 S SD  . MET D 4 204 ? 281.235 355.456 432.862 1.00 87.93  ? 204 MET B SD  1 
ATOM 4872 C CE  . MET D 4 204 ? 279.537 354.998 433.181 1.00 87.93  ? 204 MET B CE  1 
ATOM 4873 N N   . PRO D 4 205 ? 278.979 356.308 428.674 1.00 84.17  ? 205 PRO B N   1 
ATOM 4874 C CA  . PRO D 4 205 ? 277.883 356.453 427.721 1.00 84.17  ? 205 PRO B CA  1 
ATOM 4875 C C   . PRO D 4 205 ? 276.569 356.700 428.451 1.00 84.17  ? 205 PRO B C   1 
ATOM 4876 O O   . PRO D 4 205 ? 276.518 356.819 429.669 1.00 84.17  ? 205 PRO B O   1 
ATOM 4877 C CB  . PRO D 4 205 ? 277.881 355.109 427.012 1.00 84.17  ? 205 PRO B CB  1 
ATOM 4878 C CG  . PRO D 4 205 ? 278.336 354.177 428.044 1.00 84.17  ? 205 PRO B CG  1 
ATOM 4879 C CD  . PRO D 4 205 ? 279.347 354.898 428.861 1.00 84.17  ? 205 PRO B CD  1 
ATOM 4880 N N   . TYR D 4 206 ? 275.492 356.766 427.680 1.00 84.66  ? 206 TYR B N   1 
ATOM 4881 C CA  . TYR D 4 206 ? 274.165 357.029 428.223 1.00 84.66  ? 206 TYR B CA  1 
ATOM 4882 C C   . TYR D 4 206 ? 273.493 355.701 428.535 1.00 84.66  ? 206 TYR B C   1 
ATOM 4883 O O   . TYR D 4 206 ? 273.227 354.907 427.630 1.00 84.66  ? 206 TYR B O   1 
ATOM 4884 C CB  . TYR D 4 206 ? 273.343 357.842 427.233 1.00 84.66  ? 206 TYR B CB  1 
ATOM 4885 C CG  . TYR D 4 206 ? 271.944 358.131 427.691 1.00 84.66  ? 206 TYR B CG  1 
ATOM 4886 C CD1 . TYR D 4 206 ? 271.705 359.023 428.714 1.00 84.66  ? 206 TYR B CD1 1 
ATOM 4887 C CD2 . TYR D 4 206 ? 270.862 357.520 427.086 1.00 84.66  ? 206 TYR B CD2 1 
ATOM 4888 C CE1 . TYR D 4 206 ? 270.428 359.293 429.128 1.00 84.66  ? 206 TYR B CE1 1 
ATOM 4889 C CE2 . TYR D 4 206 ? 269.583 357.783 427.495 1.00 84.66  ? 206 TYR B CE2 1 
ATOM 4890 C CZ  . TYR D 4 206 ? 269.375 358.668 428.517 1.00 84.66  ? 206 TYR B CZ  1 
ATOM 4891 O OH  . TYR D 4 206 ? 268.098 358.935 428.932 1.00 84.66  ? 206 TYR B OH  1 
ATOM 4892 N N   . ILE D 4 207 ? 273.207 355.460 429.811 1.00 82.87  ? 207 ILE B N   1 
ATOM 4893 C CA  . ILE D 4 207 ? 272.656 354.192 430.277 1.00 82.87  ? 207 ILE B CA  1 
ATOM 4894 C C   . ILE D 4 207 ? 271.281 354.474 430.863 1.00 82.87  ? 207 ILE B C   1 
ATOM 4895 O O   . ILE D 4 207 ? 271.168 354.923 432.008 1.00 82.87  ? 207 ILE B O   1 
ATOM 4896 C CB  . ILE D 4 207 ? 273.560 353.518 431.307 1.00 82.87  ? 207 ILE B CB  1 
ATOM 4897 C CG1 . ILE D 4 207 ? 274.979 353.410 430.770 1.00 82.87  ? 207 ILE B CG1 1 
ATOM 4898 C CG2 . ILE D 4 207 ? 273.035 352.151 431.640 1.00 82.87  ? 207 ILE B CG2 1 
ATOM 4899 C CD1 . ILE D 4 207 ? 275.982 353.011 431.811 1.00 82.87  ? 207 ILE B CD1 1 
ATOM 4900 N N   . ASN D 4 208 ? 270.233 354.196 430.095 1.00 85.11  ? 208 ASN B N   1 
ATOM 4901 C CA  . ASN D 4 208 ? 268.869 354.375 430.566 1.00 85.11  ? 208 ASN B CA  1 
ATOM 4902 C C   . ASN D 4 208 ? 267.951 353.481 429.753 1.00 85.11  ? 208 ASN B C   1 
ATOM 4903 O O   . ASN D 4 208 ? 268.284 353.069 428.641 1.00 85.11  ? 208 ASN B O   1 
ATOM 4904 C CB  . ASN D 4 208 ? 268.417 355.828 430.462 1.00 85.11  ? 208 ASN B CB  1 
ATOM 4905 C CG  . ASN D 4 208 ? 267.320 356.159 431.433 1.00 85.11  ? 208 ASN B CG  1 
ATOM 4906 O OD1 . ASN D 4 208 ? 266.671 355.270 431.972 1.00 85.11  ? 208 ASN B OD1 1 
ATOM 4907 N ND2 . ASN D 4 208 ? 267.099 357.443 431.663 1.00 85.11  ? 208 ASN B ND2 1 
ATOM 4908 N N   . SER D 4 209 ? 266.782 353.187 430.319 1.00 87.40  ? 209 SER B N   1 
ATOM 4909 C CA  . SER D 4 209 ? 265.837 352.310 429.640 1.00 87.40  ? 209 SER B CA  1 
ATOM 4910 C C   . SER D 4 209 ? 265.139 353.019 428.489 1.00 87.40  ? 209 SER B C   1 
ATOM 4911 O O   . SER D 4 209 ? 265.155 352.528 427.358 1.00 87.40  ? 209 SER B O   1 
ATOM 4912 C CB  . SER D 4 209 ? 264.811 351.776 430.632 1.00 87.40  ? 209 SER B CB  1 
ATOM 4913 O OG  . SER D 4 209 ? 264.361 352.803 431.488 1.00 87.40  ? 209 SER B OG  1 
ATOM 4914 N N   . VAL D 4 210 ? 264.532 354.171 428.750 1.00 89.11  ? 210 VAL B N   1 
ATOM 4915 C CA  . VAL D 4 210 ? 263.892 354.958 427.703 1.00 89.11  ? 210 VAL B CA  1 
ATOM 4916 C C   . VAL D 4 210 ? 264.978 355.639 426.880 1.00 89.11  ? 210 VAL B C   1 
ATOM 4917 O O   . VAL D 4 210 ? 266.038 355.972 427.422 1.00 89.11  ? 210 VAL B O   1 
ATOM 4918 C CB  . VAL D 4 210 ? 262.915 355.976 428.301 1.00 89.11  ? 210 VAL B CB  1 
ATOM 4919 C CG1 . VAL D 4 210 ? 261.659 355.279 428.729 1.00 89.11  ? 210 VAL B CG1 1 
ATOM 4920 C CG2 . VAL D 4 210 ? 263.542 356.658 429.483 1.00 89.11  ? 210 VAL B CG2 1 
ATOM 4921 N N   . PRO D 4 211 ? 264.780 355.851 425.578 1.00 91.51  ? 211 PRO B N   1 
ATOM 4922 C CA  . PRO D 4 211 ? 265.864 356.413 424.764 1.00 91.51  ? 211 PRO B CA  1 
ATOM 4923 C C   . PRO D 4 211 ? 266.089 357.895 424.965 1.00 91.51  ? 211 PRO B C   1 
ATOM 4924 O O   . PRO D 4 211 ? 267.107 358.406 424.493 1.00 91.51  ? 211 PRO B O   1 
ATOM 4925 C CB  . PRO D 4 211 ? 265.413 356.114 423.334 1.00 91.51  ? 211 PRO B CB  1 
ATOM 4926 C CG  . PRO D 4 211 ? 263.952 356.041 423.425 1.00 91.51  ? 211 PRO B CG  1 
ATOM 4927 C CD  . PRO D 4 211 ? 263.652 355.415 424.744 1.00 91.51  ? 211 PRO B CD  1 
ATOM 4928 N N   . MET D 4 212 ? 265.189 358.605 425.635 1.00 97.58  ? 212 MET B N   1 
ATOM 4929 C CA  . MET D 4 212 ? 265.397 360.021 425.918 1.00 97.58  ? 212 MET B CA  1 
ATOM 4930 C C   . MET D 4 212 ? 264.595 360.375 427.156 1.00 97.58  ? 212 MET B C   1 
ATOM 4931 O O   . MET D 4 212 ? 263.384 360.149 427.191 1.00 97.58  ? 212 MET B O   1 
ATOM 4932 C CB  . MET D 4 212 ? 264.977 360.890 424.737 1.00 97.58  ? 212 MET B CB  1 
ATOM 4933 C CG  . MET D 4 212 ? 265.763 362.172 424.625 1.00 97.58  ? 212 MET B CG  1 
ATOM 4934 S SD  . MET D 4 212 ? 265.400 363.093 423.123 1.00 97.58  ? 212 MET B SD  1 
ATOM 4935 C CE  . MET D 4 212 ? 266.011 361.969 421.882 1.00 97.58  ? 212 MET B CE  1 
ATOM 4936 N N   . ASP D 4 213 ? 265.254 360.934 428.163 1.00 97.52  ? 213 ASP B N   1 
ATOM 4937 C CA  . ASP D 4 213 ? 264.629 361.129 429.459 1.00 97.52  ? 213 ASP B CA  1 
ATOM 4938 C C   . ASP D 4 213 ? 264.707 362.593 429.862 1.00 97.52  ? 213 ASP B C   1 
ATOM 4939 O O   . ASP D 4 213 ? 265.449 363.385 429.280 1.00 97.52  ? 213 ASP B O   1 
ATOM 4940 C CB  . ASP D 4 213 ? 265.292 360.253 430.525 1.00 97.52  ? 213 ASP B CB  1 
ATOM 4941 C CG  . ASP D 4 213 ? 264.354 359.903 431.661 1.00 97.52  ? 213 ASP B CG  1 
ATOM 4942 O OD1 . ASP D 4 213 ? 263.359 360.631 431.856 1.00 97.52  ? 213 ASP B OD1 1 
ATOM 4943 O OD2 . ASP D 4 213 ? 264.610 358.899 432.358 1.00 97.52  ? 213 ASP B OD2 1 
ATOM 4944 N N   . ASN D 4 214 ? 263.917 362.940 430.872 1.00 98.98  ? 214 ASN B N   1 
ATOM 4945 C CA  . ASN D 4 214 ? 263.954 364.269 431.459 1.00 98.98  ? 214 ASN B CA  1 
ATOM 4946 C C   . ASN D 4 214 ? 265.255 364.470 432.223 1.00 98.98  ? 214 ASN B C   1 
ATOM 4947 O O   . ASN D 4 214 ? 265.881 363.515 432.685 1.00 98.98  ? 214 ASN B O   1 
ATOM 4948 C CB  . ASN D 4 214 ? 262.763 364.454 432.393 1.00 98.98  ? 214 ASN B CB  1 
ATOM 4949 C CG  . ASN D 4 214 ? 262.559 365.885 432.790 1.00 98.98  ? 214 ASN B CG  1 
ATOM 4950 O OD1 . ASN D 4 214 ? 263.251 366.399 433.663 1.00 98.98  ? 214 ASN B OD1 1 
ATOM 4951 N ND2 . ASN D 4 214 ? 261.607 366.545 432.153 1.00 98.98  ? 214 ASN B ND2 1 
ATOM 4952 N N   . MET D 4 215 ? 265.672 365.726 432.351 1.00 99.63  ? 215 MET B N   1 
ATOM 4953 C CA  . MET D 4 215 ? 266.928 366.048 433.009 1.00 99.63  ? 215 MET B CA  1 
ATOM 4954 C C   . MET D 4 215 ? 266.751 366.737 434.351 1.00 99.63  ? 215 MET B C   1 
ATOM 4955 O O   . MET D 4 215 ? 267.747 367.136 434.956 1.00 99.63  ? 215 MET B O   1 
ATOM 4956 C CB  . MET D 4 215 ? 267.791 366.925 432.101 1.00 99.63  ? 215 MET B CB  1 
ATOM 4957 C CG  . MET D 4 215 ? 267.707 366.563 430.642 1.00 99.63  ? 215 MET B CG  1 
ATOM 4958 S SD  . MET D 4 215 ? 269.049 367.266 429.678 1.00 99.63  ? 215 MET B SD  1 
ATOM 4959 C CE  . MET D 4 215 ? 270.354 366.113 430.066 1.00 99.63  ? 215 MET B CE  1 
ATOM 4960 N N   . PHE D 4 216 ? 265.526 366.900 434.832 1.00 95.92  ? 216 PHE B N   1 
ATOM 4961 C CA  . PHE D 4 216 ? 265.312 367.478 436.149 1.00 95.92  ? 216 PHE B CA  1 
ATOM 4962 C C   . PHE D 4 216 ? 264.865 366.474 437.190 1.00 95.92  ? 216 PHE B C   1 
ATOM 4963 O O   . PHE D 4 216 ? 265.211 366.624 438.360 1.00 95.92  ? 216 PHE B O   1 
ATOM 4964 C CB  . PHE D 4 216 ? 264.274 368.598 436.086 1.00 95.92  ? 216 PHE B CB  1 
ATOM 4965 C CG  . PHE D 4 216 ? 264.845 369.927 435.730 1.00 95.92  ? 216 PHE B CG  1 
ATOM 4966 C CD1 . PHE D 4 216 ? 265.736 370.555 436.580 1.00 95.92  ? 216 PHE B CD1 1 
ATOM 4967 C CD2 . PHE D 4 216 ? 264.472 370.566 434.568 1.00 95.92  ? 216 PHE B CD2 1 
ATOM 4968 C CE1 . PHE D 4 216 ? 266.262 371.786 436.265 1.00 95.92  ? 216 PHE B CE1 1 
ATOM 4969 C CE2 . PHE D 4 216 ? 264.992 371.800 434.250 1.00 95.92  ? 216 PHE B CE2 1 
ATOM 4970 C CZ  . PHE D 4 216 ? 265.888 372.408 435.099 1.00 95.92  ? 216 PHE B CZ  1 
ATOM 4971 N N   . ARG D 4 217 ? 264.046 365.553 436.772 1.00 99.06  ? 217 ARG B N   1 
ATOM 4972 C CA  . ARG D 4 217 ? 263.520 364.581 437.625 1.00 99.06  ? 217 ARG B CA  1 
ATOM 4973 C C   . ARG D 4 217 ? 264.468 363.452 437.759 1.00 99.06  ? 217 ARG B C   1 
ATOM 4974 O O   . ARG D 4 217 ? 264.281 362.688 438.609 1.00 99.06  ? 217 ARG B O   1 
ATOM 4975 C CB  . ARG D 4 217 ? 262.256 364.054 436.992 1.00 99.06  ? 217 ARG B CB  1 
ATOM 4976 C CG  . ARG D 4 217 ? 260.940 364.626 437.498 1.00 99.06  ? 217 ARG B CG  1 
ATOM 4977 C CD  . ARG D 4 217 ? 260.637 366.047 437.025 1.00 99.06  ? 217 ARG B CD  1 
ATOM 4978 N NE  . ARG D 4 217 ? 259.257 366.297 436.561 1.00 99.06  ? 217 ARG B NE  1 
ATOM 4979 C CZ  . ARG D 4 217 ? 258.781 367.467 436.099 1.00 99.06  ? 217 ARG B CZ  1 
ATOM 4980 N NH1 . ARG D 4 217 ? 257.515 367.552 435.695 1.00 99.06  ? 217 ARG B NH1 1 
ATOM 4981 N NH2 . ARG D 4 217 ? 259.544 368.556 436.038 1.00 99.06  ? 217 ARG B NH2 1 
ATOM 4982 N N   . HIS D 4 218 ? 265.510 363.326 436.973 1.00 92.10  ? 218 HIS B N   1 
ATOM 4983 C CA  . HIS D 4 218 ? 266.347 362.150 437.071 1.00 92.10  ? 218 HIS B CA  1 
ATOM 4984 C C   . HIS D 4 218 ? 267.838 362.346 437.070 1.00 92.10  ? 218 HIS B C   1 
ATOM 4985 O O   . HIS D 4 218 ? 268.287 363.160 436.368 1.00 92.10  ? 218 HIS B O   1 
ATOM 4986 C CB  . HIS D 4 218 ? 266.055 361.412 435.843 1.00 92.10  ? 218 HIS B CB  1 
ATOM 4987 C CG  . HIS D 4 218 ? 266.382 359.986 435.928 1.00 92.10  ? 218 HIS B CG  1 
ATOM 4988 N ND1 . HIS D 4 218 ? 265.719 359.035 435.201 1.00 92.10  ? 218 HIS B ND1 1 
ATOM 4989 C CD2 . HIS D 4 218 ? 267.307 359.331 436.647 1.00 92.10  ? 218 HIS B CD2 1 
ATOM 4990 C CE1 . HIS D 4 218 ? 266.221 357.849 435.467 1.00 92.10  ? 218 HIS B CE1 1 
ATOM 4991 N NE2 . HIS D 4 218 ? 267.189 358.000 436.341 1.00 92.10  ? 218 HIS B NE2 1 
ATOM 4992 N N   . ASN D 4 219 ? 268.628 361.569 437.798 1.00 88.95  ? 219 ASN B N   1 
ATOM 4993 C CA  . ASN D 4 219 ? 270.083 361.697 437.828 1.00 88.95  ? 219 ASN B CA  1 
ATOM 4994 C C   . ASN D 4 219 ? 270.666 360.329 437.509 1.00 88.95  ? 219 ASN B C   1 
ATOM 4995 O O   . ASN D 4 219 ? 270.848 359.502 438.406 1.00 88.95  ? 219 ASN B O   1 
ATOM 4996 C CB  . ASN D 4 219 ? 270.559 362.197 439.179 1.00 88.95  ? 219 ASN B CB  1 
ATOM 4997 C CG  . ASN D 4 219 ? 269.843 363.442 439.615 1.00 88.95  ? 219 ASN B CG  1 
ATOM 4998 O OD1 . ASN D 4 219 ? 269.488 364.280 438.794 1.00 88.95  ? 219 ASN B OD1 1 
ATOM 4999 N ND2 . ASN D 4 219 ? 269.623 363.573 440.913 1.00 88.95  ? 219 ASN B ND2 1 
ATOM 5000 N N   . ASN D 4 220 ? 270.973 360.092 436.241 1.00 88.30  ? 220 ASN B N   1 
ATOM 5001 C CA  . ASN D 4 220 ? 271.308 358.753 435.784 1.00 88.30  ? 220 ASN B CA  1 
ATOM 5002 C C   . ASN D 4 220 ? 272.736 358.334 436.094 1.00 88.30  ? 220 ASN B C   1 
ATOM 5003 O O   . ASN D 4 220 ? 273.081 357.179 435.840 1.00 88.30  ? 220 ASN B O   1 
ATOM 5004 C CB  . ASN D 4 220 ? 271.063 358.640 434.285 1.00 88.30  ? 220 ASN B CB  1 
ATOM 5005 C CG  . ASN D 4 220 ? 271.670 359.779 433.522 1.00 88.30  ? 220 ASN B CG  1 
ATOM 5006 O OD1 . ASN D 4 220 ? 272.280 360.667 434.104 1.00 88.30  ? 220 ASN B OD1 1 
ATOM 5007 N ND2 . ASN D 4 220 ? 271.511 359.764 432.211 1.00 88.30  ? 220 ASN B ND2 1 
ATOM 5008 N N   . LEU D 4 221 ? 273.576 359.218 436.617 1.00 80.73  ? 221 LEU B N   1 
ATOM 5009 C CA  . LEU D 4 221 ? 274.925 358.842 437.005 1.00 80.73  ? 221 LEU B CA  1 
ATOM 5010 C C   . LEU D 4 221 ? 275.214 359.410 438.380 1.00 80.73  ? 221 LEU B C   1 
ATOM 5011 O O   . LEU D 4 221 ? 274.454 360.216 438.911 1.00 80.73  ? 221 LEU B O   1 
ATOM 5012 C CB  . LEU D 4 221 ? 275.971 359.331 436.003 1.00 80.73  ? 221 LEU B CB  1 
ATOM 5013 C CG  . LEU D 4 221 ? 276.090 358.514 434.723 1.00 80.73  ? 221 LEU B CG  1 
ATOM 5014 C CD1 . LEU D 4 221 ? 277.217 359.029 433.873 1.00 80.73  ? 221 LEU B CD1 1 
ATOM 5015 C CD2 . LEU D 4 221 ? 276.319 357.066 435.040 1.00 80.73  ? 221 LEU B CD2 1 
ATOM 5016 N N   . THR D 4 222 ? 276.325 358.971 438.959 1.00 79.67  ? 222 THR B N   1 
ATOM 5017 C CA  . THR D 4 222 ? 276.783 359.492 440.242 1.00 79.67  ? 222 THR B CA  1 
ATOM 5018 C C   . THR D 4 222 ? 278.275 359.241 440.324 1.00 79.67  ? 222 THR B C   1 
ATOM 5019 O O   . THR D 4 222 ? 278.706 358.092 440.241 1.00 79.67  ? 222 THR B O   1 
ATOM 5020 C CB  . THR D 4 222 ? 276.069 358.822 441.405 1.00 79.67  ? 222 THR B CB  1 
ATOM 5021 O OG1 . THR D 4 222 ? 274.709 359.257 441.441 1.00 79.67  ? 222 THR B OG1 1 
ATOM 5022 C CG2 . THR D 4 222 ? 276.730 359.189 442.709 1.00 79.67  ? 222 THR B CG2 1 
ATOM 5023 N N   . LEU D 4 223 ? 279.055 360.296 440.474 1.00 75.43  ? 223 LEU B N   1 
ATOM 5024 C CA  . LEU D 4 223 ? 280.503 360.184 440.547 1.00 75.43  ? 223 LEU B CA  1 
ATOM 5025 C C   . LEU D 4 223 ? 280.917 360.185 442.009 1.00 75.43  ? 223 LEU B C   1 
ATOM 5026 O O   . LEU D 4 223 ? 280.600 361.125 442.739 1.00 75.43  ? 223 LEU B O   1 
ATOM 5027 C CB  . LEU D 4 223 ? 281.158 361.334 439.794 1.00 75.43  ? 223 LEU B CB  1 
ATOM 5028 C CG  . LEU D 4 223 ? 282.639 361.522 440.057 1.00 75.43  ? 223 LEU B CG  1 
ATOM 5029 C CD1 . LEU D 4 223 ? 283.408 360.421 439.393 1.00 75.43  ? 223 LEU B CD1 1 
ATOM 5030 C CD2 . LEU D 4 223 ? 283.073 362.855 439.525 1.00 75.43  ? 223 LEU B CD2 1 
ATOM 5031 N N   . MET D 4 224 ? 281.610 359.139 442.441 1.00 76.72  ? 224 MET B N   1 
ATOM 5032 C CA  . MET D 4 224 ? 282.012 358.987 443.831 1.00 76.72  ? 224 MET B CA  1 
ATOM 5033 C C   . MET D 4 224 ? 283.523 358.952 443.940 1.00 76.72  ? 224 MET B C   1 
ATOM 5034 O O   . MET D 4 224 ? 284.198 358.356 443.100 1.00 76.72  ? 224 MET B O   1 
ATOM 5035 C CB  . MET D 4 224 ? 281.449 357.714 444.436 1.00 76.72  ? 224 MET B CB  1 
ATOM 5036 C CG  . MET D 4 224 ? 279.969 357.734 444.652 1.00 76.72  ? 224 MET B CG  1 
ATOM 5037 S SD  . MET D 4 224 ? 279.436 356.313 445.604 1.00 76.72  ? 224 MET B SD  1 
ATOM 5038 C CE  . MET D 4 224 ? 277.742 356.767 445.928 1.00 76.72  ? 224 MET B CE  1 
ATOM 5039 N N   . ILE D 4 225 ? 284.053 359.577 444.983 1.00 72.82  ? 225 ILE B N   1 
ATOM 5040 C CA  . ILE D 4 225 ? 285.478 359.574 445.275 1.00 72.82  ? 225 ILE B CA  1 
ATOM 5041 C C   . ILE D 4 225 ? 285.618 359.161 446.728 1.00 72.82  ? 225 ILE B C   1 
ATOM 5042 O O   . ILE D 4 225 ? 285.114 359.851 447.616 1.00 72.82  ? 225 ILE B O   1 
ATOM 5043 C CB  . ILE D 4 225 ? 286.123 360.940 445.035 1.00 72.82  ? 225 ILE B CB  1 
ATOM 5044 C CG1 . ILE D 4 225 ? 286.171 361.249 443.550 1.00 72.82  ? 225 ILE B CG1 1 
ATOM 5045 C CG2 . ILE D 4 225 ? 287.508 360.969 445.602 1.00 72.82  ? 225 ILE B CG2 1 
ATOM 5046 C CD1 . ILE D 4 225 ? 286.716 362.600 443.249 1.00 72.82  ? 225 ILE B CD1 1 
ATOM 5047 N N   . ILE D 4 226 ? 286.286 358.036 446.977 1.00 75.76  ? 226 ILE B N   1 
ATOM 5048 C CA  . ILE D 4 226 ? 286.409 357.481 448.315 1.00 75.76  ? 226 ILE B CA  1 
ATOM 5049 C C   . ILE D 4 226 ? 287.880 357.248 448.634 1.00 75.76  ? 226 ILE B C   1 
ATOM 5050 O O   . ILE D 4 226 ? 288.562 356.531 447.899 1.00 75.76  ? 226 ILE B O   1 
ATOM 5051 C CB  . ILE D 4 226 ? 285.622 356.170 448.472 1.00 75.76  ? 226 ILE B CB  1 
ATOM 5052 C CG1 . ILE D 4 226 ? 284.130 356.432 448.353 1.00 75.76  ? 226 ILE B CG1 1 
ATOM 5053 C CG2 . ILE D 4 226 ? 285.908 355.549 449.807 1.00 75.76  ? 226 ILE B CG2 1 
ATOM 5054 C CD1 . ILE D 4 226 ? 283.296 355.200 448.478 1.00 75.76  ? 226 ILE B CD1 1 
ATOM 5055 N N   . PRO D 4 227 ? 288.421 357.830 449.701 1.00 76.12  ? 227 PRO B N   1 
ATOM 5056 C CA  . PRO D 4 227 ? 289.806 357.557 450.097 1.00 76.12  ? 227 PRO B CA  1 
ATOM 5057 C C   . PRO D 4 227 ? 289.894 356.293 450.935 1.00 76.12  ? 227 PRO B C   1 
ATOM 5058 O O   . PRO D 4 227 ? 289.404 356.248 452.066 1.00 76.12  ? 227 PRO B O   1 
ATOM 5059 C CB  . PRO D 4 227 ? 290.182 358.802 450.912 1.00 76.12  ? 227 PRO B CB  1 
ATOM 5060 C CG  . PRO D 4 227 ? 289.021 359.719 450.818 1.00 76.12  ? 227 PRO B CG  1 
ATOM 5061 C CD  . PRO D 4 227 ? 287.841 358.893 450.519 1.00 76.12  ? 227 PRO B CD  1 
ATOM 5062 N N   . PHE D 4 228 ? 290.539 355.263 450.386 1.00 79.04  ? 228 PHE B N   1 
ATOM 5063 C CA  . PHE D 4 228 ? 290.694 354.014 451.124 1.00 79.04  ? 228 PHE B CA  1 
ATOM 5064 C C   . PHE D 4 228 ? 291.825 354.097 452.135 1.00 79.04  ? 228 PHE B C   1 
ATOM 5065 O O   . PHE D 4 228 ? 291.606 353.947 453.338 1.00 79.04  ? 228 PHE B O   1 
ATOM 5066 C CB  . PHE D 4 228 ? 290.921 352.857 450.160 1.00 79.04  ? 228 PHE B CB  1 
ATOM 5067 C CG  . PHE D 4 228 ? 289.665 352.204 449.713 1.00 79.04  ? 228 PHE B CG  1 
ATOM 5068 C CD1 . PHE D 4 228 ? 288.524 352.283 450.475 1.00 79.04  ? 228 PHE B CD1 1 
ATOM 5069 C CD2 . PHE D 4 228 ? 289.618 351.526 448.525 1.00 79.04  ? 228 PHE B CD2 1 
ATOM 5070 C CE1 . PHE D 4 228 ? 287.365 351.685 450.063 1.00 79.04  ? 228 PHE B CE1 1 
ATOM 5071 C CE2 . PHE D 4 228 ? 288.460 350.928 448.110 1.00 79.04  ? 228 PHE B CE2 1 
ATOM 5072 C CZ  . PHE D 4 228 ? 287.333 351.008 448.879 1.00 79.04  ? 228 PHE B CZ  1 
ATOM 5073 N N   . VAL D 4 229 ? 293.047 354.316 451.666 1.00 80.30  ? 229 VAL B N   1 
ATOM 5074 C CA  . VAL D 4 229 ? 294.190 354.541 452.542 1.00 80.30  ? 229 VAL B CA  1 
ATOM 5075 C C   . VAL D 4 229 ? 294.318 356.047 452.742 1.00 80.30  ? 229 VAL B C   1 
ATOM 5076 O O   . VAL D 4 229 ? 294.573 356.765 451.765 1.00 80.30  ? 229 VAL B O   1 
ATOM 5077 C CB  . VAL D 4 229 ? 295.473 353.947 451.956 1.00 80.30  ? 229 VAL B CB  1 
ATOM 5078 C CG1 . VAL D 4 229 ? 296.613 354.151 452.913 1.00 80.30  ? 229 VAL B CG1 1 
ATOM 5079 C CG2 . VAL D 4 229 ? 295.271 352.482 451.699 1.00 80.30  ? 229 VAL B CG2 1 
ATOM 5080 N N   . PRO D 4 230 ? 294.154 356.556 453.954 1.00 79.65  ? 230 PRO B N   1 
ATOM 5081 C CA  . PRO D 4 230 ? 293.997 357.996 454.148 1.00 79.65  ? 230 PRO B CA  1 
ATOM 5082 C C   . PRO D 4 230 ? 295.316 358.730 453.987 1.00 79.65  ? 230 PRO B C   1 
ATOM 5083 O O   . PRO D 4 230 ? 296.390 358.136 453.947 1.00 79.65  ? 230 PRO B O   1 
ATOM 5084 C CB  . PRO D 4 230 ? 293.490 358.092 455.582 1.00 79.65  ? 230 PRO B CB  1 
ATOM 5085 C CG  . PRO D 4 230 ? 294.127 356.943 456.246 1.00 79.65  ? 230 PRO B CG  1 
ATOM 5086 C CD  . PRO D 4 230 ? 294.173 355.837 455.234 1.00 79.65  ? 230 PRO B CD  1 
ATOM 5087 N N   . LEU D 4 231 ? 295.205 360.049 453.886 1.00 82.60  ? 231 LEU B N   1 
ATOM 5088 C CA  . LEU D 4 231 ? 296.357 360.901 453.664 1.00 82.60  ? 231 LEU B CA  1 
ATOM 5089 C C   . LEU D 4 231 ? 297.260 360.911 454.884 1.00 82.60  ? 231 LEU B C   1 
ATOM 5090 O O   . LEU D 4 231 ? 296.802 360.851 456.024 1.00 82.60  ? 231 LEU B O   1 
ATOM 5091 C CB  . LEU D 4 231 ? 295.903 362.320 453.351 1.00 82.60  ? 231 LEU B CB  1 
ATOM 5092 C CG  . LEU D 4 231 ? 296.936 363.273 452.786 1.00 82.60  ? 231 LEU B CG  1 
ATOM 5093 C CD1 . LEU D 4 231 ? 297.110 362.981 451.334 1.00 82.60  ? 231 LEU B CD1 1 
ATOM 5094 C CD2 . LEU D 4 231 ? 296.478 364.679 452.986 1.00 82.60  ? 231 LEU B CD2 1 
ATOM 5095 N N   . ASN D 4 232 ? 298.562 360.969 454.636 1.00 83.81  ? 232 ASN B N   1 
ATOM 5096 C CA  . ASN D 4 232 ? 299.515 361.074 455.722 1.00 83.81  ? 232 ASN B CA  1 
ATOM 5097 C C   . ASN D 4 232 ? 300.728 361.839 455.227 1.00 83.81  ? 232 ASN B C   1 
ATOM 5098 O O   . ASN D 4 232 ? 301.109 361.736 454.062 1.00 83.81  ? 232 ASN B O   1 
ATOM 5099 C CB  . ASN D 4 232 ? 299.919 359.701 456.244 1.00 83.81  ? 232 ASN B CB  1 
ATOM 5100 C CG  . ASN D 4 232 ? 300.143 359.701 457.725 1.00 83.81  ? 232 ASN B CG  1 
ATOM 5101 O OD1 . ASN D 4 232 ? 299.986 360.726 458.381 1.00 83.81  ? 232 ASN B OD1 1 
ATOM 5102 N ND2 . ASN D 4 232 ? 300.503 358.549 458.272 1.00 83.81  ? 232 ASN B ND2 1 
ATOM 5103 N N   . TYR D 4 233 ? 301.323 362.610 456.126 1.00 87.83  ? 233 TYR B N   1 
ATOM 5104 C CA  . TYR D 4 233 ? 302.464 363.442 455.782 1.00 87.83  ? 233 TYR B CA  1 
ATOM 5105 C C   . TYR D 4 233 ? 303.260 363.693 457.048 1.00 87.83  ? 233 TYR B C   1 
ATOM 5106 O O   . TYR D 4 233 ? 302.784 363.458 458.159 1.00 87.83  ? 233 TYR B O   1 
ATOM 5107 C CB  . TYR D 4 233 ? 302.020 364.758 455.149 1.00 87.83  ? 233 TYR B CB  1 
ATOM 5108 C CG  . TYR D 4 233 ? 300.829 365.385 455.825 1.00 87.83  ? 233 TYR B CG  1 
ATOM 5109 C CD1 . TYR D 4 233 ? 300.975 366.144 456.973 1.00 87.83  ? 233 TYR B CD1 1 
ATOM 5110 C CD2 . TYR D 4 233 ? 299.561 365.231 455.305 1.00 87.83  ? 233 TYR B CD2 1 
ATOM 5111 C CE1 . TYR D 4 233 ? 299.895 366.713 457.590 1.00 87.83  ? 233 TYR B CE1 1 
ATOM 5112 C CE2 . TYR D 4 233 ? 298.473 365.800 455.917 1.00 87.83  ? 233 TYR B CE2 1 
ATOM 5113 C CZ  . TYR D 4 233 ? 298.648 366.539 457.057 1.00 87.83  ? 233 TYR B CZ  1 
ATOM 5114 O OH  . TYR D 4 233 ? 297.562 367.107 457.667 1.00 87.83  ? 233 TYR B OH  1 
ATOM 5115 N N   . SER D 4 234 ? 304.468 364.199 456.873 1.00 99.85  ? 234 SER B N   1 
ATOM 5116 C CA  . SER D 4 234 ? 305.274 364.565 458.020 1.00 99.85  ? 234 SER B CA  1 
ATOM 5117 C C   . SER D 4 234 ? 304.892 365.962 458.486 1.00 99.85  ? 234 SER B C   1 
ATOM 5118 O O   . SER D 4 234 ? 304.023 366.620 457.915 1.00 99.85  ? 234 SER B O   1 
ATOM 5119 C CB  . SER D 4 234 ? 306.754 364.497 457.676 1.00 99.85  ? 234 SER B CB  1 
ATOM 5120 O OG  . SER D 4 234 ? 306.989 365.078 456.408 1.00 99.85  ? 234 SER B OG  1 
ATOM 5121 N N   . GLU D 4 235 ? 305.553 366.426 459.534 1.00 105.34 ? 235 GLU B N   1 
ATOM 5122 C CA  . GLU D 4 235 ? 305.328 367.776 460.023 1.00 105.34 ? 235 GLU B CA  1 
ATOM 5123 C C   . GLU D 4 235 ? 306.079 368.760 459.142 1.00 105.34 ? 235 GLU B C   1 
ATOM 5124 O O   . GLU D 4 235 ? 307.293 368.636 458.959 1.00 105.34 ? 235 GLU B O   1 
ATOM 5125 C CB  . GLU D 4 235 ? 305.777 367.898 461.477 1.00 105.34 ? 235 GLU B CB  1 
ATOM 5126 C CG  . GLU D 4 235 ? 306.045 369.321 461.975 1.00 105.34 ? 235 GLU B CG  1 
ATOM 5127 C CD  . GLU D 4 235 ? 304.859 370.279 461.879 1.00 105.34 ? 235 GLU B CD  1 
ATOM 5128 O OE1 . GLU D 4 235 ? 305.106 371.502 461.918 1.00 105.34 ? 235 GLU B OE1 1 
ATOM 5129 O OE2 . GLU D 4 235 ? 303.689 369.838 461.848 1.00 105.34 ? 235 GLU B OE2 1 
ATOM 5130 N N   . GLY D 4 236 ? 305.363 369.729 458.591 1.00 99.31  ? 236 GLY B N   1 
ATOM 5131 C CA  . GLY D 4 236 ? 305.999 370.732 457.766 1.00 99.31  ? 236 GLY B CA  1 
ATOM 5132 C C   . GLY D 4 236 ? 305.385 370.828 456.390 1.00 99.31  ? 236 GLY B C   1 
ATOM 5133 O O   . GLY D 4 236 ? 305.319 371.914 455.809 1.00 99.31  ? 236 GLY B O   1 
ATOM 5134 N N   . SER D 4 237 ? 304.930 369.699 455.857 1.00 93.42  ? 237 SER B N   1 
ATOM 5135 C CA  . SER D 4 237 ? 304.324 369.691 454.539 1.00 93.42  ? 237 SER B CA  1 
ATOM 5136 C C   . SER D 4 237 ? 302.939 370.323 454.589 1.00 93.42  ? 237 SER B C   1 
ATOM 5137 O O   . SER D 4 237 ? 302.363 370.540 455.657 1.00 93.42  ? 237 SER B O   1 
ATOM 5138 C CB  . SER D 4 237 ? 304.243 368.270 454.001 1.00 93.42  ? 237 SER B CB  1 
ATOM 5139 O OG  . SER D 4 237 ? 305.537 367.771 453.730 1.00 93.42  ? 237 SER B OG  1 
ATOM 5140 N N   . SER D 4 238 ? 302.411 370.632 453.414 1.00 90.37  ? 238 SER B N   1 
ATOM 5141 C CA  . SER D 4 238 ? 301.112 371.282 453.327 1.00 90.37  ? 238 SER B CA  1 
ATOM 5142 C C   . SER D 4 238 ? 300.024 370.292 453.709 1.00 90.37  ? 238 SER B C   1 
ATOM 5143 O O   . SER D 4 238 ? 299.990 369.183 453.172 1.00 90.37  ? 238 SER B O   1 
ATOM 5144 C CB  . SER D 4 238 ? 300.875 371.808 451.924 1.00 90.37  ? 238 SER B CB  1 
ATOM 5145 O OG  . SER D 4 238 ? 301.046 370.773 450.980 1.00 90.37  ? 238 SER B OG  1 
ATOM 5146 N N   . PRO D 4 239 ? 299.132 370.644 454.617 1.00 89.21  ? 239 PRO B N   1 
ATOM 5147 C CA  . PRO D 4 239 ? 298.236 369.642 455.201 1.00 89.21  ? 239 PRO B CA  1 
ATOM 5148 C C   . PRO D 4 239 ? 296.967 369.363 454.414 1.00 89.21  ? 239 PRO B C   1 
ATOM 5149 O O   . PRO D 4 239 ? 296.018 368.819 454.979 1.00 89.21  ? 239 PRO B O   1 
ATOM 5150 C CB  . PRO D 4 239 ? 297.908 370.244 456.566 1.00 89.21  ? 239 PRO B CB  1 
ATOM 5151 C CG  . PRO D 4 239 ? 297.969 371.698 456.336 1.00 89.21  ? 239 PRO B CG  1 
ATOM 5152 C CD  . PRO D 4 239 ? 299.030 371.939 455.306 1.00 89.21  ? 239 PRO B CD  1 
ATOM 5153 N N   . TYR D 4 240 ? 296.912 369.722 453.135 1.00 90.31  ? 240 TYR B N   1 
ATOM 5154 C CA  . TYR D 4 240 ? 295.765 369.354 452.321 1.00 90.31  ? 240 TYR B CA  1 
ATOM 5155 C C   . TYR D 4 240 ? 296.199 369.178 450.877 1.00 90.31  ? 240 TYR B C   1 
ATOM 5156 O O   . TYR D 4 240 ? 297.079 369.884 450.389 1.00 90.31  ? 240 TYR B O   1 
ATOM 5157 C CB  . TYR D 4 240 ? 294.640 370.388 452.407 1.00 90.31  ? 240 TYR B CB  1 
ATOM 5158 C CG  . TYR D 4 240 ? 295.093 371.817 452.302 1.00 90.31  ? 240 TYR B CG  1 
ATOM 5159 C CD1 . TYR D 4 240 ? 295.283 372.418 451.063 1.00 90.31  ? 240 TYR B CD1 1 
ATOM 5160 C CD2 . TYR D 4 240 ? 295.303 372.579 453.440 1.00 90.31  ? 240 TYR B CD2 1 
ATOM 5161 C CE1 . TYR D 4 240 ? 295.696 373.729 450.959 1.00 90.31  ? 240 TYR B CE1 1 
ATOM 5162 C CE2 . TYR D 4 240 ? 295.715 373.897 453.348 1.00 90.31  ? 240 TYR B CE2 1 
ATOM 5163 C CZ  . TYR D 4 240 ? 295.909 374.465 452.104 1.00 90.31  ? 240 TYR B CZ  1 
ATOM 5164 O OH  . TYR D 4 240 ? 296.314 375.775 452.002 1.00 90.31  ? 240 TYR B OH  1 
ATOM 5165 N N   . VAL D 4 241 ? 295.570 368.227 450.199 1.00 84.27  ? 241 VAL B N   1 
ATOM 5166 C CA  . VAL D 4 241 ? 295.830 367.972 448.788 1.00 84.27  ? 241 VAL B CA  1 
ATOM 5167 C C   . VAL D 4 241 ? 294.562 368.227 447.986 1.00 84.27  ? 241 VAL B C   1 
ATOM 5168 O O   . VAL D 4 241 ? 293.605 367.457 448.101 1.00 84.27  ? 241 VAL B O   1 
ATOM 5169 C CB  . VAL D 4 241 ? 296.317 366.539 448.561 1.00 84.27  ? 241 VAL B CB  1 
ATOM 5170 C CG1 . VAL D 4 241 ? 296.770 366.384 447.146 1.00 84.27  ? 241 VAL B CG1 1 
ATOM 5171 C CG2 . VAL D 4 241 ? 297.439 366.214 449.499 1.00 84.27  ? 241 VAL B CG2 1 
ATOM 5172 N N   . PRO D 4 242 ? 294.505 369.264 447.161 1.00 82.21  ? 242 PRO B N   1 
ATOM 5173 C CA  . PRO D 4 242 ? 293.261 369.576 446.459 1.00 82.21  ? 242 PRO B CA  1 
ATOM 5174 C C   . PRO D 4 242 ? 293.019 368.654 445.277 1.00 82.21  ? 242 PRO B C   1 
ATOM 5175 O O   . PRO D 4 242 ? 293.954 368.198 444.619 1.00 82.21  ? 242 PRO B O   1 
ATOM 5176 C CB  . PRO D 4 242 ? 293.482 371.014 445.996 1.00 82.21  ? 242 PRO B CB  1 
ATOM 5177 C CG  . PRO D 4 242 ? 294.936 371.114 445.838 1.00 82.21  ? 242 PRO B CG  1 
ATOM 5178 C CD  . PRO D 4 242 ? 295.545 370.266 446.901 1.00 82.21  ? 242 PRO B CD  1 
ATOM 5179 N N   . ILE D 4 243 ? 291.744 368.382 445.017 1.00 80.53  ? 243 ILE B N   1 
ATOM 5180 C CA  . ILE D 4 243 ? 291.298 367.534 443.917 1.00 80.53  ? 243 ILE B CA  1 
ATOM 5181 C C   . ILE D 4 243 ? 290.533 368.398 442.928 1.00 80.53  ? 243 ILE B C   1 
ATOM 5182 O O   . ILE D 4 243 ? 289.802 369.306 443.329 1.00 80.53  ? 243 ILE B O   1 
ATOM 5183 C CB  . ILE D 4 243 ? 290.414 366.380 444.426 1.00 80.53  ? 243 ILE B CB  1 
ATOM 5184 C CG1 . ILE D 4 243 ? 290.999 365.787 445.695 1.00 80.53  ? 243 ILE B CG1 1 
ATOM 5185 C CG2 . ILE D 4 243 ? 290.303 365.292 443.401 1.00 80.53  ? 243 ILE B CG2 1 
ATOM 5186 C CD1 . ILE D 4 243 ? 290.142 364.730 446.301 1.00 80.53  ? 243 ILE B CD1 1 
ATOM 5187 N N   . THR D 4 244 ? 290.691 368.120 441.639 1.00 81.50  ? 244 THR B N   1 
ATOM 5188 C CA  . THR D 4 244 ? 290.051 368.908 440.593 1.00 81.50  ? 244 THR B CA  1 
ATOM 5189 C C   . THR D 4 244 ? 289.288 367.984 439.662 1.00 81.50  ? 244 THR B C   1 
ATOM 5190 O O   . THR D 4 244 ? 289.876 367.072 439.078 1.00 81.50  ? 244 THR B O   1 
ATOM 5191 C CB  . THR D 4 244 ? 291.089 369.705 439.811 1.00 81.50  ? 244 THR B CB  1 
ATOM 5192 O OG1 . THR D 4 244 ? 291.742 370.619 440.694 1.00 81.50  ? 244 THR B OG1 1 
ATOM 5193 C CG2 . THR D 4 244 ? 290.434 370.473 438.689 1.00 81.50  ? 244 THR B CG2 1 
ATOM 5194 N N   . VAL D 4 245 ? 287.991 368.224 439.508 1.00 80.28  ? 245 VAL B N   1 
ATOM 5195 C CA  . VAL D 4 245 ? 287.131 367.415 438.655 1.00 80.28  ? 245 VAL B CA  1 
ATOM 5196 C C   . VAL D 4 245 ? 286.730 368.252 437.455 1.00 80.28  ? 245 VAL B C   1 
ATOM 5197 O O   . VAL D 4 245 ? 286.297 369.397 437.609 1.00 80.28  ? 245 VAL B O   1 
ATOM 5198 C CB  . VAL D 4 245 ? 285.895 366.925 439.411 1.00 80.28  ? 245 VAL B CB  1 
ATOM 5199 C CG1 . VAL D 4 245 ? 285.145 365.919 438.586 1.00 80.28  ? 245 VAL B CG1 1 
ATOM 5200 C CG2 . VAL D 4 245 ? 286.310 366.323 440.718 1.00 80.28  ? 245 VAL B CG2 1 
ATOM 5201 N N   . THR D 4 246 ? 286.857 367.684 436.261 1.00 83.22  ? 246 THR B N   1 
ATOM 5202 C CA  . THR D 4 246 ? 286.562 368.384 435.021 1.00 83.22  ? 246 THR B CA  1 
ATOM 5203 C C   . THR D 4 246 ? 285.679 367.507 434.152 1.00 83.22  ? 246 THR B C   1 
ATOM 5204 O O   . THR D 4 246 ? 286.090 366.417 433.751 1.00 83.22  ? 246 THR B O   1 
ATOM 5205 C CB  . THR D 4 246 ? 287.847 368.732 434.280 1.00 83.22  ? 246 THR B CB  1 
ATOM 5206 O OG1 . THR D 4 246 ? 288.607 369.661 435.059 1.00 83.22  ? 246 THR B OG1 1 
ATOM 5207 C CG2 . THR D 4 246 ? 287.529 369.348 432.956 1.00 83.22  ? 246 THR B CG2 1 
ATOM 5208 N N   . ILE D 4 247 ? 284.478 367.984 433.852 1.00 83.25  ? 247 ILE B N   1 
ATOM 5209 C CA  . ILE D 4 247 ? 283.471 367.219 433.129 1.00 83.25  ? 247 ILE B CA  1 
ATOM 5210 C C   . ILE D 4 247 ? 283.234 367.883 431.785 1.00 83.25  ? 247 ILE B C   1 
ATOM 5211 O O   . ILE D 4 247 ? 283.286 369.111 431.678 1.00 83.25  ? 247 ILE B O   1 
ATOM 5212 C CB  . ILE D 4 247 ? 282.168 367.138 433.943 1.00 83.25  ? 247 ILE B CB  1 
ATOM 5213 C CG1 . ILE D 4 247 ? 282.487 366.823 435.396 1.00 83.25  ? 247 ILE B CG1 1 
ATOM 5214 C CG2 . ILE D 4 247 ? 281.257 366.076 433.409 1.00 83.25  ? 247 ILE B CG2 1 
ATOM 5215 C CD1 . ILE D 4 247 ? 281.319 366.949 436.308 1.00 83.25  ? 247 ILE B CD1 1 
ATOM 5216 N N   . ALA D 4 248 ? 282.985 367.081 430.763 1.00 89.63  ? 248 ALA B N   1 
ATOM 5217 C CA  . ALA D 4 248 ? 282.662 367.622 429.453 1.00 89.63  ? 248 ALA B CA  1 
ATOM 5218 C C   . ALA D 4 248 ? 281.592 366.777 428.785 1.00 89.63  ? 248 ALA B C   1 
ATOM 5219 O O   . ALA D 4 248 ? 281.799 365.575 428.588 1.00 89.63  ? 248 ALA B O   1 
ATOM 5220 C CB  . ALA D 4 248 ? 283.905 367.677 428.574 1.00 89.63  ? 248 ALA B CB  1 
ATOM 5221 N N   . PRO D 4 249 ? 280.450 367.353 428.425 1.00 91.34  ? 249 PRO B N   1 
ATOM 5222 C CA  . PRO D 4 249 ? 279.391 366.567 427.787 1.00 91.34  ? 249 PRO B CA  1 
ATOM 5223 C C   . PRO D 4 249 ? 279.770 366.159 426.378 1.00 91.34  ? 249 PRO B C   1 
ATOM 5224 O O   . PRO D 4 249 ? 280.411 366.912 425.645 1.00 91.34  ? 249 PRO B O   1 
ATOM 5225 C CB  . PRO D 4 249 ? 278.198 367.527 427.775 1.00 91.34  ? 249 PRO B CB  1 
ATOM 5226 C CG  . PRO D 4 249 ? 278.553 368.601 428.719 1.00 91.34  ? 249 PRO B CG  1 
ATOM 5227 C CD  . PRO D 4 249 ? 280.023 368.732 428.669 1.00 91.34  ? 249 PRO B CD  1 
ATOM 5228 N N   . MET D 4 250 ? 279.376 364.949 426.003 1.00 98.59  ? 250 MET B N   1 
ATOM 5229 C CA  . MET D 4 250 ? 279.723 364.389 424.707 1.00 98.59  ? 250 MET B CA  1 
ATOM 5230 C C   . MET D 4 250 ? 278.483 363.828 424.035 1.00 98.59  ? 250 MET B C   1 
ATOM 5231 O O   . MET D 4 250 ? 277.761 363.028 424.637 1.00 98.59  ? 250 MET B O   1 
ATOM 5232 C CB  . MET D 4 250 ? 280.777 363.297 424.849 1.00 98.59  ? 250 MET B CB  1 
ATOM 5233 C CG  . MET D 4 250 ? 282.194 363.820 424.798 1.00 98.59  ? 250 MET B CG  1 
ATOM 5234 S SD  . MET D 4 250 ? 283.444 362.528 424.878 1.00 98.59  ? 250 MET B SD  1 
ATOM 5235 C CE  . MET D 4 250 ? 282.651 361.232 423.942 1.00 98.59  ? 250 MET B CE  1 
ATOM 5236 N N   . CYS D 4 251 ? 278.256 364.257 422.790 1.00 103.79 ? 251 CYS B N   1 
ATOM 5237 C CA  . CYS D 4 251 ? 277.186 363.778 421.912 1.00 103.79 ? 251 CYS B CA  1 
ATOM 5238 C C   . CYS D 4 251 ? 275.807 363.988 422.535 1.00 103.79 ? 251 CYS B C   1 
ATOM 5239 O O   . CYS D 4 251 ? 275.030 363.054 422.725 1.00 103.79 ? 251 CYS B O   1 
ATOM 5240 C CB  . CYS D 4 251 ? 277.404 362.313 421.525 1.00 103.79 ? 251 CYS B CB  1 
ATOM 5241 S SG  . CYS D 4 251 ? 278.870 362.039 420.516 1.00 103.79 ? 251 CYS B SG  1 
ATOM 5242 N N   . ALA D 4 252 ? 275.515 365.243 422.845 1.00 103.97 ? 252 ALA B N   1 
ATOM 5243 C CA  . ALA D 4 252 ? 274.244 365.612 423.444 1.00 103.97 ? 252 ALA B CA  1 
ATOM 5244 C C   . ALA D 4 252 ? 273.231 365.934 422.361 1.00 103.97 ? 252 ALA B C   1 
ATOM 5245 O O   . ALA D 4 252 ? 273.576 366.509 421.328 1.00 103.97 ? 252 ALA B O   1 
ATOM 5246 C CB  . ALA D 4 252 ? 274.413 366.817 424.364 1.00 103.97 ? 252 ALA B CB  1 
ATOM 5247 N N   . GLU D 4 253 ? 271.978 365.561 422.598 1.00 105.50 ? 253 GLU B N   1 
ATOM 5248 C CA  . GLU D 4 253 ? 270.904 365.927 421.690 1.00 105.50 ? 253 GLU B CA  1 
ATOM 5249 C C   . GLU D 4 253 ? 269.615 366.082 422.473 1.00 105.50 ? 253 GLU B C   1 
ATOM 5250 O O   . GLU D 4 253 ? 269.277 365.234 423.298 1.00 105.50 ? 253 GLU B O   1 
ATOM 5251 C CB  . GLU D 4 253 ? 270.726 364.896 420.577 1.00 105.50 ? 253 GLU B CB  1 
ATOM 5252 C CG  . GLU D 4 253 ? 270.887 363.471 421.014 1.00 105.50 ? 253 GLU B CG  1 
ATOM 5253 C CD  . GLU D 4 253 ? 270.835 362.513 419.846 1.00 105.50 ? 253 GLU B CD  1 
ATOM 5254 O OE1 . GLU D 4 253 ? 271.850 361.837 419.581 1.00 105.50 ? 253 GLU B OE1 1 
ATOM 5255 O OE2 . GLU D 4 253 ? 269.781 362.440 419.183 1.00 105.50 ? 253 GLU B OE2 1 
ATOM 5256 N N   . TYR D 4 254 ? 268.902 367.162 422.202 1.00 107.26 ? 254 TYR B N   1 
ATOM 5257 C CA  . TYR D 4 254 ? 267.680 367.507 422.906 1.00 107.26 ? 254 TYR B CA  1 
ATOM 5258 C C   . TYR D 4 254 ? 266.494 367.279 421.980 1.00 107.26 ? 254 TYR B C   1 
ATOM 5259 O O   . TYR D 4 254 ? 266.637 366.742 420.886 1.00 107.26 ? 254 TYR B O   1 
ATOM 5260 C CB  . TYR D 4 254 ? 267.744 368.945 423.404 1.00 107.26 ? 254 TYR B CB  1 
ATOM 5261 C CG  . TYR D 4 254 ? 268.955 369.230 424.240 1.00 107.26 ? 254 TYR B CG  1 
ATOM 5262 C CD1 . TYR D 4 254 ? 269.005 368.855 425.572 1.00 107.26 ? 254 TYR B CD1 1 
ATOM 5263 C CD2 . TYR D 4 254 ? 270.048 369.878 423.702 1.00 107.26 ? 254 TYR B CD2 1 
ATOM 5264 C CE1 . TYR D 4 254 ? 270.112 369.118 426.342 1.00 107.26 ? 254 TYR B CE1 1 
ATOM 5265 C CE2 . TYR D 4 254 ? 271.158 370.144 424.462 1.00 107.26 ? 254 TYR B CE2 1 
ATOM 5266 C CZ  . TYR D 4 254 ? 271.184 369.764 425.777 1.00 107.26 ? 254 TYR B CZ  1 
ATOM 5267 O OH  . TYR D 4 254 ? 272.298 370.035 426.525 1.00 107.26 ? 254 TYR B OH  1 
ATOM 5268 N N   . ASN D 4 255 ? 265.314 367.695 422.422 1.00 111.88 ? 255 ASN B N   1 
ATOM 5269 C CA  . ASN D 4 255 ? 264.079 367.339 421.734 1.00 111.88 ? 255 ASN B CA  1 
ATOM 5270 C C   . ASN D 4 255 ? 263.151 368.542 421.765 1.00 111.88 ? 255 ASN B C   1 
ATOM 5271 O O   . ASN D 4 255 ? 262.632 368.891 422.826 1.00 111.88 ? 255 ASN B O   1 
ATOM 5272 C CB  . ASN D 4 255 ? 263.444 366.120 422.405 1.00 111.88 ? 255 ASN B CB  1 
ATOM 5273 C CG  . ASN D 4 255 ? 262.053 365.793 421.884 1.00 111.88 ? 255 ASN B CG  1 
ATOM 5274 O OD1 . ASN D 4 255 ? 261.060 366.427 422.241 1.00 111.88 ? 255 ASN B OD1 1 
ATOM 5275 N ND2 . ASN D 4 255 ? 261.977 364.759 421.056 1.00 111.88 ? 255 ASN B ND2 1 
ATOM 5276 N N   . GLY D 4 256 ? 262.924 369.158 420.612 1.00 116.54 ? 256 GLY B N   1 
ATOM 5277 C CA  . GLY D 4 256 ? 261.953 370.236 420.548 1.00 116.54 ? 256 GLY B CA  1 
ATOM 5278 C C   . GLY D 4 256 ? 261.964 370.918 419.199 1.00 116.54 ? 256 GLY B C   1 
ATOM 5279 O O   . GLY D 4 256 ? 262.832 370.676 418.356 1.00 116.54 ? 256 GLY B O   1 
ATOM 5280 N N   . LEU D 4 257 ? 260.965 371.778 419.009 1.00 118.30 ? 257 LEU B N   1 
ATOM 5281 C CA  . LEU D 4 257 ? 260.884 372.650 417.843 1.00 118.30 ? 257 LEU B CA  1 
ATOM 5282 C C   . LEU D 4 257 ? 260.907 374.102 418.295 1.00 118.30 ? 257 LEU B C   1 
ATOM 5283 O O   . LEU D 4 257 ? 261.639 374.921 417.742 1.00 118.30 ? 257 LEU B O   1 
ATOM 5284 C CB  . LEU D 4 257 ? 259.618 372.370 417.027 1.00 118.30 ? 257 LEU B CB  1 
ATOM 5285 C CG  . LEU D 4 257 ? 259.362 373.210 415.769 1.00 118.30 ? 257 LEU B CG  1 
ATOM 5286 C CD1 . LEU D 4 257 ? 260.583 373.270 414.864 1.00 118.30 ? 257 LEU B CD1 1 
ATOM 5287 C CD2 . LEU D 4 257 ? 258.157 372.687 414.999 1.00 118.30 ? 257 LEU B CD2 1 
ATOM 5288 N N   . GLY E 5 1   ? 237.787 308.854 417.918 1.00 111.37 ? 1   GLY C N   1 
ATOM 5289 C CA  . GLY E 5 1   ? 238.879 309.490 417.206 1.00 111.37 ? 1   GLY C CA  1 
ATOM 5290 C C   . GLY E 5 1   ? 240.210 308.813 417.451 1.00 111.37 ? 1   GLY C C   1 
ATOM 5291 O O   . GLY E 5 1   ? 240.303 307.592 417.446 1.00 111.37 ? 1   GLY C O   1 
ATOM 5292 N N   . LEU E 5 2   ? 241.241 309.615 417.662 1.00 107.48 ? 2   LEU C N   1 
ATOM 5293 C CA  . LEU E 5 2   ? 242.568 309.089 417.934 1.00 107.48 ? 2   LEU C CA  1 
ATOM 5294 C C   . LEU E 5 2   ? 242.614 308.553 419.357 1.00 107.48 ? 2   LEU C C   1 
ATOM 5295 O O   . LEU E 5 2   ? 242.389 309.317 420.297 1.00 107.48 ? 2   LEU C O   1 
ATOM 5296 C CB  . LEU E 5 2   ? 243.600 310.185 417.752 1.00 107.48 ? 2   LEU C CB  1 
ATOM 5297 C CG  . LEU E 5 2   ? 245.061 309.870 418.042 1.00 107.48 ? 2   LEU C CG  1 
ATOM 5298 C CD1 . LEU E 5 2   ? 245.520 308.659 417.256 1.00 107.48 ? 2   LEU C CD1 1 
ATOM 5299 C CD2 . LEU E 5 2   ? 245.918 311.073 417.720 1.00 107.48 ? 2   LEU C CD2 1 
ATOM 5300 N N   . PRO E 5 3   ? 242.885 307.272 419.564 1.00 101.64 ? 3   PRO C N   1 
ATOM 5301 C CA  . PRO E 5 3   ? 242.875 306.738 420.930 1.00 101.64 ? 3   PRO C CA  1 
ATOM 5302 C C   . PRO E 5 3   ? 244.142 307.063 421.695 1.00 101.64 ? 3   PRO C C   1 
ATOM 5303 O O   . PRO E 5 3   ? 245.239 306.727 421.250 1.00 101.64 ? 3   PRO C O   1 
ATOM 5304 C CB  . PRO E 5 3   ? 242.733 305.226 420.717 1.00 101.64 ? 3   PRO C CB  1 
ATOM 5305 C CG  . PRO E 5 3   ? 242.459 305.045 419.263 1.00 101.64 ? 3   PRO C CG  1 
ATOM 5306 C CD  . PRO E 5 3   ? 243.069 306.205 418.579 1.00 101.64 ? 3   PRO C CD  1 
ATOM 5307 N N   . VAL E 5 4   ? 244.004 307.702 422.851 1.00 99.19  ? 4   VAL C N   1 
ATOM 5308 C CA  . VAL E 5 4   ? 245.136 308.054 423.687 1.00 99.19  ? 4   VAL C CA  1 
ATOM 5309 C C   . VAL E 5 4   ? 245.043 307.281 424.995 1.00 99.19  ? 4   VAL C C   1 
ATOM 5310 O O   . VAL E 5 4   ? 244.078 306.569 425.255 1.00 99.19  ? 4   VAL C O   1 
ATOM 5311 C CB  . VAL E 5 4   ? 245.208 309.561 423.947 1.00 99.19  ? 4   VAL C CB  1 
ATOM 5312 C CG1 . VAL E 5 4   ? 245.284 310.306 422.646 1.00 99.19  ? 4   VAL C CG1 1 
ATOM 5313 C CG2 . VAL E 5 4   ? 244.003 309.994 424.725 1.00 99.19  ? 4   VAL C CG2 1 
ATOM 5314 N N   . MET E 5 5   ? 246.063 307.439 425.831 1.00 101.78 ? 5   MET C N   1 
ATOM 5315 C CA  . MET E 5 5   ? 246.144 306.701 427.087 1.00 101.78 ? 5   MET C CA  1 
ATOM 5316 C C   . MET E 5 5   ? 247.082 307.465 428.007 1.00 101.78 ? 5   MET C C   1 
ATOM 5317 O O   . MET E 5 5   ? 248.283 307.526 427.738 1.00 101.78 ? 5   MET C O   1 
ATOM 5318 C CB  . MET E 5 5   ? 246.646 305.291 426.843 1.00 101.78 ? 5   MET C CB  1 
ATOM 5319 C CG  . MET E 5 5   ? 246.854 304.477 428.091 1.00 101.78 ? 5   MET C CG  1 
ATOM 5320 S SD  . MET E 5 5   ? 248.055 303.160 427.847 1.00 101.78 ? 5   MET C SD  1 
ATOM 5321 C CE  . MET E 5 5   ? 247.613 302.581 426.213 1.00 101.78 ? 5   MET C CE  1 
ATOM 5322 N N   . THR E 5 6   ? 246.548 308.035 429.079 1.00 96.09  ? 6   THR C N   1 
ATOM 5323 C CA  . THR E 5 6   ? 247.333 308.911 429.934 1.00 96.09  ? 6   THR C CA  1 
ATOM 5324 C C   . THR E 5 6   ? 248.254 308.115 430.847 1.00 96.09  ? 6   THR C C   1 
ATOM 5325 O O   . THR E 5 6   ? 247.835 307.155 431.492 1.00 96.09  ? 6   THR C O   1 
ATOM 5326 C CB  . THR E 5 6   ? 246.418 309.790 430.777 1.00 96.09  ? 6   THR C CB  1 
ATOM 5327 O OG1 . THR E 5 6   ? 245.693 308.968 431.691 1.00 96.09  ? 6   THR C OG1 1 
ATOM 5328 C CG2 . THR E 5 6   ? 245.436 310.510 429.896 1.00 96.09  ? 6   THR C CG2 1 
ATOM 5329 N N   . THR E 5 7   ? 249.509 308.530 430.908 1.00 93.22  ? 7   THR C N   1 
ATOM 5330 C CA  . THR E 5 7   ? 250.491 307.902 431.773 1.00 93.22  ? 7   THR C CA  1 
ATOM 5331 C C   . THR E 5 7   ? 250.323 308.431 433.188 1.00 93.22  ? 7   THR C C   1 
ATOM 5332 O O   . THR E 5 7   ? 249.585 309.388 433.411 1.00 93.22  ? 7   THR C O   1 
ATOM 5333 C CB  . THR E 5 7   ? 251.892 308.191 431.245 1.00 93.22  ? 7   THR C CB  1 
ATOM 5334 O OG1 . THR E 5 7   ? 252.287 309.504 431.646 1.00 93.22  ? 7   THR C OG1 1 
ATOM 5335 C CG2 . THR E 5 7   ? 251.918 308.109 429.741 1.00 93.22  ? 7   THR C CG2 1 
ATOM 5336 N N   . PRO E 5 8   ? 250.961 307.810 434.184 1.00 91.93  ? 8   PRO C N   1 
ATOM 5337 C CA  . PRO E 5 8   ? 251.056 308.459 435.492 1.00 91.93  ? 8   PRO C CA  1 
ATOM 5338 C C   . PRO E 5 8   ? 251.890 309.725 435.427 1.00 91.93  ? 8   PRO C C   1 
ATOM 5339 O O   . PRO E 5 8   ? 252.775 309.875 434.586 1.00 91.93  ? 8   PRO C O   1 
ATOM 5340 C CB  . PRO E 5 8   ? 251.724 307.398 436.372 1.00 91.93  ? 8   PRO C CB  1 
ATOM 5341 C CG  . PRO E 5 8   ? 252.230 306.377 435.441 1.00 91.93  ? 8   PRO C CG  1 
ATOM 5342 C CD  . PRO E 5 8   ? 251.286 306.383 434.302 1.00 91.93  ? 8   PRO C CD  1 
ATOM 5343 N N   . GLY E 5 9   ? 251.595 310.639 436.340 1.00 90.91  ? 9   GLY C N   1 
ATOM 5344 C CA  . GLY E 5 9   ? 252.210 311.945 436.312 1.00 90.91  ? 9   GLY C CA  1 
ATOM 5345 C C   . GLY E 5 9   ? 251.546 312.884 435.340 1.00 90.91  ? 9   GLY C C   1 
ATOM 5346 O O   . GLY E 5 9   ? 252.234 313.598 434.604 1.00 90.91  ? 9   GLY C O   1 
ATOM 5347 N N   . SER E 5 10  ? 250.217 312.895 435.299 1.00 89.82  ? 10  SER C N   1 
ATOM 5348 C CA  . SER E 5 10  ? 249.493 313.674 434.308 1.00 89.82  ? 10  SER C CA  1 
ATOM 5349 C C   . SER E 5 10  ? 249.034 315.030 434.833 1.00 89.82  ? 10  SER C C   1 
ATOM 5350 O O   . SER E 5 10  ? 249.472 316.066 434.333 1.00 89.82  ? 10  SER C O   1 
ATOM 5351 C CB  . SER E 5 10  ? 248.306 312.857 433.798 1.00 89.82  ? 10  SER C CB  1 
ATOM 5352 O OG  . SER E 5 10  ? 247.224 312.955 434.692 1.00 89.82  ? 10  SER C OG  1 
ATOM 5353 N N   . THR E 5 11  ? 248.172 315.053 435.838 1.00 87.82  ? 11  THR C N   1 
ATOM 5354 C CA  . THR E 5 11  ? 247.648 316.321 436.345 1.00 87.82  ? 11  THR C CA  1 
ATOM 5355 C C   . THR E 5 11  ? 248.408 316.772 437.588 1.00 87.82  ? 11  THR C C   1 
ATOM 5356 O O   . THR E 5 11  ? 247.839 316.988 438.653 1.00 87.82  ? 11  THR C O   1 
ATOM 5357 C CB  . THR E 5 11  ? 246.157 316.204 436.635 1.00 87.82  ? 11  THR C CB  1 
ATOM 5358 O OG1 . THR E 5 11  ? 245.958 315.447 437.835 1.00 87.82  ? 11  THR C OG1 1 
ATOM 5359 C CG2 . THR E 5 11  ? 245.427 315.551 435.485 1.00 87.82  ? 11  THR C CG2 1 
ATOM 5360 N N   . GLN E 5 12  ? 249.714 316.930 437.440 1.00 82.53  ? 12  GLN C N   1 
ATOM 5361 C CA  . GLN E 5 12  ? 250.552 317.364 438.541 1.00 82.53  ? 12  GLN C CA  1 
ATOM 5362 C C   . GLN E 5 12  ? 251.258 318.654 438.168 1.00 82.53  ? 12  GLN C C   1 
ATOM 5363 O O   . GLN E 5 12  ? 251.462 318.962 436.993 1.00 82.53  ? 12  GLN C O   1 
ATOM 5364 C CB  . GLN E 5 12  ? 251.579 316.299 438.918 1.00 82.53  ? 12  GLN C CB  1 
ATOM 5365 C CG  . GLN E 5 12  ? 252.551 315.981 437.822 1.00 82.53  ? 12  GLN C CG  1 
ATOM 5366 C CD  . GLN E 5 12  ? 253.791 315.322 438.338 1.00 82.53  ? 12  GLN C CD  1 
ATOM 5367 O OE1 . GLN E 5 12  ? 253.916 315.070 439.530 1.00 82.53  ? 12  GLN C OE1 1 
ATOM 5368 N NE2 . GLN E 5 12  ? 254.726 315.041 437.447 1.00 82.53  ? 12  GLN C NE2 1 
ATOM 5369 N N   . PHE E 5 13  ? 251.621 319.412 439.185 1.00 79.46  ? 13  PHE C N   1 
ATOM 5370 C CA  . PHE E 5 13  ? 252.284 320.694 439.019 1.00 79.46  ? 13  PHE C CA  1 
ATOM 5371 C C   . PHE E 5 13  ? 253.693 320.537 439.567 1.00 79.46  ? 13  PHE C C   1 
ATOM 5372 O O   . PHE E 5 13  ? 253.932 320.698 440.760 1.00 79.46  ? 13  PHE C O   1 
ATOM 5373 C CB  . PHE E 5 13  ? 251.522 321.793 439.731 1.00 79.46  ? 13  PHE C CB  1 
ATOM 5374 C CG  . PHE E 5 13  ? 252.241 323.101 439.776 1.00 79.46  ? 13  PHE C CG  1 
ATOM 5375 C CD1 . PHE E 5 13  ? 252.796 323.644 438.636 1.00 79.46  ? 13  PHE C CD1 1 
ATOM 5376 C CD2 . PHE E 5 13  ? 252.354 323.792 440.959 1.00 79.46  ? 13  PHE C CD2 1 
ATOM 5377 C CE1 . PHE E 5 13  ? 253.460 324.842 438.682 1.00 79.46  ? 13  PHE C CE1 1 
ATOM 5378 C CE2 . PHE E 5 13  ? 253.013 324.993 441.009 1.00 79.46  ? 13  PHE C CE2 1 
ATOM 5379 C CZ  . PHE E 5 13  ? 253.566 325.517 439.869 1.00 79.46  ? 13  PHE C CZ  1 
ATOM 5380 N N   . LEU E 5 14  ? 254.624 320.203 438.689 1.00 81.44  ? 14  LEU C N   1 
ATOM 5381 C CA  . LEU E 5 14  ? 256.026 320.182 439.061 1.00 81.44  ? 14  LEU C CA  1 
ATOM 5382 C C   . LEU E 5 14  ? 256.556 321.602 439.008 1.00 81.44  ? 14  LEU C C   1 
ATOM 5383 O O   . LEU E 5 14  ? 256.333 322.314 438.027 1.00 81.44  ? 14  LEU C O   1 
ATOM 5384 C CB  . LEU E 5 14  ? 256.809 319.280 438.119 1.00 81.44  ? 14  LEU C CB  1 
ATOM 5385 C CG  . LEU E 5 14  ? 258.122 318.731 438.646 1.00 81.44  ? 14  LEU C CG  1 
ATOM 5386 C CD1 . LEU E 5 14  ? 257.919 318.139 440.006 1.00 81.44  ? 14  LEU C CD1 1 
ATOM 5387 C CD2 . LEU E 5 14  ? 258.630 317.685 437.703 1.00 81.44  ? 14  LEU C CD2 1 
ATOM 5388 N N   . THR E 5 15  ? 257.246 322.028 440.064 1.00 85.37  ? 15  THR C N   1 
ATOM 5389 C CA  . THR E 5 15  ? 257.658 323.422 440.134 1.00 85.37  ? 15  THR C CA  1 
ATOM 5390 C C   . THR E 5 15  ? 258.827 323.733 439.218 1.00 85.37  ? 15  THR C C   1 
ATOM 5391 O O   . THR E 5 15  ? 259.085 324.906 438.947 1.00 85.37  ? 15  THR C O   1 
ATOM 5392 C CB  . THR E 5 15  ? 258.023 323.797 441.560 1.00 85.37  ? 15  THR C CB  1 
ATOM 5393 O OG1 . THR E 5 15  ? 259.088 322.957 442.006 1.00 85.37  ? 15  THR C OG1 1 
ATOM 5394 C CG2 . THR E 5 15  ? 256.842 323.606 442.463 1.00 85.37  ? 15  THR C CG2 1 
ATOM 5395 N N   . SER E 5 16  ? 259.533 322.724 438.728 1.00 89.66  ? 16  SER C N   1 
ATOM 5396 C CA  . SER E 5 16  ? 260.652 322.935 437.824 1.00 89.66  ? 16  SER C CA  1 
ATOM 5397 C C   . SER E 5 16  ? 260.372 322.380 436.433 1.00 89.66  ? 16  SER C C   1 
ATOM 5398 O O   . SER E 5 16  ? 261.245 321.768 435.820 1.00 89.66  ? 16  SER C O   1 
ATOM 5399 C CB  . SER E 5 16  ? 261.920 322.312 438.395 1.00 89.66  ? 16  SER C CB  1 
ATOM 5400 O OG  . SER E 5 16  ? 261.854 320.902 438.338 1.00 89.66  ? 16  SER C OG  1 
ATOM 5401 N N   . ASP E 5 17  ? 259.162 322.581 435.927 1.00 99.51  ? 17  ASP C N   1 
ATOM 5402 C CA  . ASP E 5 17  ? 258.792 322.023 434.639 1.00 99.51  ? 17  ASP C CA  1 
ATOM 5403 C C   . ASP E 5 17  ? 259.180 322.966 433.506 1.00 99.51  ? 17  ASP C C   1 
ATOM 5404 O O   . ASP E 5 17  ? 259.804 324.009 433.707 1.00 99.51  ? 17  ASP C O   1 
ATOM 5405 C CB  . ASP E 5 17  ? 257.299 321.701 434.602 1.00 99.51  ? 17  ASP C CB  1 
ATOM 5406 C CG  . ASP E 5 17  ? 256.411 322.899 434.943 1.00 99.51  ? 17  ASP C CG  1 
ATOM 5407 O OD1 . ASP E 5 17  ? 256.915 324.014 435.184 1.00 99.51  ? 17  ASP C OD1 1 
ATOM 5408 O OD2 . ASP E 5 17  ? 255.175 322.721 434.967 1.00 99.51  ? 17  ASP C OD2 1 
ATOM 5409 N N   . ASP E 5 18  ? 258.786 322.590 432.294 1.00 115.26 ? 18  ASP C N   1 
ATOM 5410 C CA  . ASP E 5 18  ? 258.961 323.427 431.109 1.00 115.26 ? 18  ASP C CA  1 
ATOM 5411 C C   . ASP E 5 18  ? 257.876 322.974 430.133 1.00 115.26 ? 18  ASP C C   1 
ATOM 5412 O O   . ASP E 5 18  ? 257.992 321.922 429.505 1.00 115.26 ? 18  ASP C O   1 
ATOM 5413 C CB  . ASP E 5 18  ? 260.353 323.281 430.515 1.00 115.26 ? 18  ASP C CB  1 
ATOM 5414 C CG  . ASP E 5 18  ? 260.514 324.003 429.179 1.00 115.26 ? 18  ASP C CG  1 
ATOM 5415 O OD1 . ASP E 5 18  ? 259.753 324.950 428.881 1.00 115.26 ? 18  ASP C OD1 1 
ATOM 5416 O OD2 . ASP E 5 18  ? 261.467 323.665 428.447 1.00 115.26 ? 18  ASP C OD2 1 
ATOM 5417 N N   . PHE E 5 19  ? 256.834 323.780 430.016 1.00 113.01 ? 19  PHE C N   1 
ATOM 5418 C CA  . PHE E 5 19  ? 255.738 323.490 429.113 1.00 113.01 ? 19  PHE C CA  1 
ATOM 5419 C C   . PHE E 5 19  ? 255.315 324.769 428.415 1.00 113.01 ? 19  PHE C C   1 
ATOM 5420 O O   . PHE E 5 19  ? 255.590 325.875 428.881 1.00 113.01 ? 19  PHE C O   1 
ATOM 5421 C CB  . PHE E 5 19  ? 254.550 322.880 429.857 1.00 113.01 ? 19  PHE C CB  1 
ATOM 5422 C CG  . PHE E 5 19  ? 254.793 321.489 430.343 1.00 113.01 ? 19  PHE C CG  1 
ATOM 5423 C CD1 . PHE E 5 19  ? 255.113 320.480 429.458 1.00 113.01 ? 19  PHE C CD1 1 
ATOM 5424 C CD2 . PHE E 5 19  ? 254.700 321.190 431.686 1.00 113.01 ? 19  PHE C CD2 1 
ATOM 5425 C CE1 . PHE E 5 19  ? 255.334 319.195 429.904 1.00 113.01 ? 19  PHE C CE1 1 
ATOM 5426 C CE2 . PHE E 5 19  ? 254.921 319.909 432.139 1.00 113.01 ? 19  PHE C CE2 1 
ATOM 5427 C CZ  . PHE E 5 19  ? 255.239 318.910 431.246 1.00 113.01 ? 19  PHE C CZ  1 
ATOM 5428 N N   . GLN E 5 20  ? 254.647 324.605 427.282 1.00 117.14 ? 20  GLN C N   1 
ATOM 5429 C CA  . GLN E 5 20  ? 254.076 325.751 426.602 1.00 117.14 ? 20  GLN C CA  1 
ATOM 5430 C C   . GLN E 5 20  ? 252.883 326.269 427.394 1.00 117.14 ? 20  GLN C C   1 
ATOM 5431 O O   . GLN E 5 20  ? 252.036 325.503 427.855 1.00 117.14 ? 20  GLN C O   1 
ATOM 5432 C CB  . GLN E 5 20  ? 253.653 325.375 425.185 1.00 117.14 ? 20  GLN C CB  1 
ATOM 5433 C CG  . GLN E 5 20  ? 253.226 326.550 424.327 1.00 117.14 ? 20  GLN C CG  1 
ATOM 5434 C CD  . GLN E 5 20  ? 254.060 327.786 424.584 1.00 117.14 ? 20  GLN C CD  1 
ATOM 5435 O OE1 . GLN E 5 20  ? 253.586 328.757 425.170 1.00 117.14 ? 20  GLN C OE1 1 
ATOM 5436 N NE2 . GLN E 5 20  ? 255.311 327.758 424.143 1.00 117.14 ? 20  GLN C NE2 1 
ATOM 5437 N N   . SER E 5 21  ? 252.826 327.582 427.557 1.00 108.85 ? 21  SER C N   1 
ATOM 5438 C CA  . SER E 5 21  ? 251.851 328.195 428.437 1.00 108.85 ? 21  SER C CA  1 
ATOM 5439 C C   . SER E 5 21  ? 250.921 329.107 427.656 1.00 108.85 ? 21  SER C C   1 
ATOM 5440 O O   . SER E 5 21  ? 251.354 329.785 426.721 1.00 108.85 ? 21  SER C O   1 
ATOM 5441 C CB  . SER E 5 21  ? 252.556 328.998 429.532 1.00 108.85 ? 21  SER C CB  1 
ATOM 5442 O OG  . SER E 5 21  ? 252.930 330.263 429.035 1.00 108.85 ? 21  SER C OG  1 
ATOM 5443 N N   . PRO E 5 22  ? 249.639 329.144 428.015 1.00 103.75 ? 22  PRO C N   1 
ATOM 5444 C CA  . PRO E 5 22  ? 248.700 330.007 427.289 1.00 103.75 ? 22  PRO C CA  1 
ATOM 5445 C C   . PRO E 5 22  ? 248.898 331.468 427.666 1.00 103.75 ? 22  PRO C C   1 
ATOM 5446 O O   . PRO E 5 22  ? 249.023 331.809 428.843 1.00 103.75 ? 22  PRO C O   1 
ATOM 5447 C CB  . PRO E 5 22  ? 247.330 329.489 427.734 1.00 103.75 ? 22  PRO C CB  1 
ATOM 5448 C CG  . PRO E 5 22  ? 247.578 328.878 429.055 1.00 103.75 ? 22  PRO C CG  1 
ATOM 5449 C CD  . PRO E 5 22  ? 248.959 328.311 429.018 1.00 103.75 ? 22  PRO C CD  1 
ATOM 5450 N N   . SER E 5 23  ? 248.929 332.330 426.658 1.00 98.93  ? 23  SER C N   1 
ATOM 5451 C CA  . SER E 5 23  ? 249.169 333.744 426.900 1.00 98.93  ? 23  SER C CA  1 
ATOM 5452 C C   . SER E 5 23  ? 247.885 334.421 427.348 1.00 98.93  ? 23  SER C C   1 
ATOM 5453 O O   . SER E 5 23  ? 246.805 334.118 426.838 1.00 98.93  ? 23  SER C O   1 
ATOM 5454 C CB  . SER E 5 23  ? 249.707 334.410 425.642 1.00 98.93  ? 23  SER C CB  1 
ATOM 5455 O OG  . SER E 5 23  ? 249.885 335.796 425.850 1.00 98.93  ? 23  SER C OG  1 
ATOM 5456 N N   . ALA E 5 24  ? 248.000 335.338 428.308 1.00 98.20  ? 24  ALA C N   1 
ATOM 5457 C CA  . ALA E 5 24  ? 246.815 336.025 428.807 1.00 98.20  ? 24  ALA C CA  1 
ATOM 5458 C C   . ALA E 5 24  ? 246.428 337.179 427.897 1.00 98.20  ? 24  ALA C C   1 
ATOM 5459 O O   . ALA E 5 24  ? 245.244 337.384 427.611 1.00 98.20  ? 24  ALA C O   1 
ATOM 5460 C CB  . ALA E 5 24  ? 247.045 336.527 430.228 1.00 98.20  ? 24  ALA C CB  1 
ATOM 5461 N N   . MET E 5 25  ? 247.411 337.950 427.440 1.00 101.99 ? 25  MET C N   1 
ATOM 5462 C CA  . MET E 5 25  ? 247.175 339.111 426.587 1.00 101.99 ? 25  MET C CA  1 
ATOM 5463 C C   . MET E 5 25  ? 247.838 338.884 425.238 1.00 101.99 ? 25  MET C C   1 
ATOM 5464 O O   . MET E 5 25  ? 249.011 339.236 425.050 1.00 101.99 ? 25  MET C O   1 
ATOM 5465 C CB  . MET E 5 25  ? 247.707 340.386 427.232 1.00 101.99 ? 25  MET C CB  1 
ATOM 5466 C CG  . MET E 5 25  ? 247.012 340.769 428.508 1.00 101.99 ? 25  MET C CG  1 
ATOM 5467 S SD  . MET E 5 25  ? 247.559 342.372 429.106 1.00 101.99 ? 25  MET C SD  1 
ATOM 5468 C CE  . MET E 5 25  ? 247.107 343.407 427.722 1.00 101.99 ? 25  MET C CE  1 
ATOM 5469 N N   . PRO E 5 26  ? 247.137 338.312 424.275 1.00 102.19 ? 26  PRO C N   1 
ATOM 5470 C CA  . PRO E 5 26  ? 247.654 338.313 422.905 1.00 102.19 ? 26  PRO C CA  1 
ATOM 5471 C C   . PRO E 5 26  ? 247.353 339.637 422.232 1.00 102.19 ? 26  PRO C C   1 
ATOM 5472 O O   . PRO E 5 26  ? 246.786 340.529 422.872 1.00 102.19 ? 26  PRO C O   1 
ATOM 5473 C CB  . PRO E 5 26  ? 246.909 337.152 422.238 1.00 102.19 ? 26  PRO C CB  1 
ATOM 5474 C CG  . PRO E 5 26  ? 246.143 336.477 423.330 1.00 102.19 ? 26  PRO C CG  1 
ATOM 5475 C CD  . PRO E 5 26  ? 245.921 337.504 424.380 1.00 102.19 ? 26  PRO C CD  1 
ATOM 5476 N N   . GLN E 5 27  ? 247.713 339.744 420.945 1.00 107.17 ? 27  GLN C N   1 
ATOM 5477 C CA  . GLN E 5 27  ? 247.633 340.957 420.104 1.00 107.17 ? 27  GLN C CA  1 
ATOM 5478 C C   . GLN E 5 27  ? 248.125 342.221 420.820 1.00 107.17 ? 27  GLN C C   1 
ATOM 5479 O O   . GLN E 5 27  ? 247.568 343.309 420.665 1.00 107.17 ? 27  GLN C O   1 
ATOM 5480 C CB  . GLN E 5 27  ? 246.225 341.147 419.500 1.00 107.17 ? 27  GLN C CB  1 
ATOM 5481 C CG  . GLN E 5 27  ? 245.020 341.446 420.405 1.00 107.17 ? 27  GLN C CG  1 
ATOM 5482 C CD  . GLN E 5 27  ? 244.255 340.209 420.784 1.00 107.17 ? 27  GLN C CD  1 
ATOM 5483 O OE1 . GLN E 5 27  ? 244.724 339.095 420.583 1.00 107.17 ? 27  GLN C OE1 1 
ATOM 5484 N NE2 . GLN E 5 27  ? 243.063 340.394 421.334 1.00 107.17 ? 27  GLN C NE2 1 
ATOM 5485 N N   . PHE E 5 28  ? 249.214 342.107 421.575 1.00 105.73 ? 28  PHE C N   1 
ATOM 5486 C CA  . PHE E 5 28  ? 249.692 343.252 422.334 1.00 105.73 ? 28  PHE C CA  1 
ATOM 5487 C C   . PHE E 5 28  ? 250.704 344.109 421.589 1.00 105.73 ? 28  PHE C C   1 
ATOM 5488 O O   . PHE E 5 28  ? 250.756 345.320 421.844 1.00 105.73 ? 28  PHE C O   1 
ATOM 5489 C CB  . PHE E 5 28  ? 250.306 342.808 423.663 1.00 105.73 ? 28  PHE C CB  1 
ATOM 5490 C CG  . PHE E 5 28  ? 250.667 343.952 424.543 1.00 105.73 ? 28  PHE C CG  1 
ATOM 5491 C CD1 . PHE E 5 28  ? 249.682 344.750 425.082 1.00 105.73 ? 28  PHE C CD1 1 
ATOM 5492 C CD2 . PHE E 5 28  ? 251.985 344.276 424.774 1.00 105.73 ? 28  PHE C CD2 1 
ATOM 5493 C CE1 . PHE E 5 28  ? 250.005 345.825 425.867 1.00 105.73 ? 28  PHE C CE1 1 
ATOM 5494 C CE2 . PHE E 5 28  ? 252.313 345.351 425.557 1.00 105.73 ? 28  PHE C CE2 1 
ATOM 5495 C CZ  . PHE E 5 28  ? 251.322 346.127 426.100 1.00 105.73 ? 28  PHE C CZ  1 
ATOM 5496 N N   . ASP E 5 29  ? 251.486 343.522 420.674 1.00 112.06 ? 29  ASP C N   1 
ATOM 5497 C CA  . ASP E 5 29  ? 252.526 344.208 419.894 1.00 112.06 ? 29  ASP C CA  1 
ATOM 5498 C C   . ASP E 5 29  ? 253.573 344.844 420.815 1.00 112.06 ? 29  ASP C C   1 
ATOM 5499 O O   . ASP E 5 29  ? 253.661 346.062 420.968 1.00 112.06 ? 29  ASP C O   1 
ATOM 5500 C CB  . ASP E 5 29  ? 251.928 345.237 418.924 1.00 112.06 ? 29  ASP C CB  1 
ATOM 5501 C CG  . ASP E 5 29  ? 252.849 345.549 417.770 1.00 112.06 ? 29  ASP C CG  1 
ATOM 5502 O OD1 . ASP E 5 29  ? 253.757 346.389 417.944 1.00 112.06 ? 29  ASP C OD1 1 
ATOM 5503 O OD2 . ASP E 5 29  ? 252.670 344.955 416.688 1.00 112.06 ? 29  ASP C OD2 1 
ATOM 5504 N N   . VAL E 5 30  ? 254.336 343.953 421.450 1.00 103.63 ? 30  VAL C N   1 
ATOM 5505 C CA  . VAL E 5 30  ? 255.293 344.231 422.520 1.00 103.63 ? 30  VAL C CA  1 
ATOM 5506 C C   . VAL E 5 30  ? 256.346 345.264 422.114 1.00 103.63 ? 30  VAL C C   1 
ATOM 5507 O O   . VAL E 5 30  ? 256.604 345.475 420.924 1.00 103.63 ? 30  VAL C O   1 
ATOM 5508 C CB  . VAL E 5 30  ? 255.936 342.902 422.966 1.00 103.63 ? 30  VAL C CB  1 
ATOM 5509 C CG1 . VAL E 5 30  ? 257.034 342.462 422.016 1.00 103.63 ? 30  VAL C CG1 1 
ATOM 5510 C CG2 . VAL E 5 30  ? 256.425 342.956 424.390 1.00 103.63 ? 30  VAL C CG2 1 
ATOM 5511 N N   . THR E 5 31  ? 256.919 345.949 423.099 1.00 100.69 ? 31  THR C N   1 
ATOM 5512 C CA  . THR E 5 31  ? 257.894 347.001 422.838 1.00 100.69 ? 31  THR C CA  1 
ATOM 5513 C C   . THR E 5 31  ? 259.211 346.399 422.365 1.00 100.69 ? 31  THR C C   1 
ATOM 5514 O O   . THR E 5 31  ? 259.736 345.490 423.015 1.00 100.69 ? 31  THR C O   1 
ATOM 5515 C CB  . THR E 5 31  ? 258.118 347.812 424.106 1.00 100.69 ? 31  THR C CB  1 
ATOM 5516 O OG1 . THR E 5 31  ? 256.862 348.310 424.577 1.00 100.69 ? 31  THR C OG1 1 
ATOM 5517 C CG2 . THR E 5 31  ? 259.033 348.979 423.845 1.00 100.69 ? 31  THR C CG2 1 
ATOM 5518 N N   . PRO E 5 32  ? 259.781 346.873 421.257 1.00 101.15 ? 32  PRO C N   1 
ATOM 5519 C CA  . PRO E 5 32  ? 261.021 346.274 420.748 1.00 101.15 ? 32  PRO C CA  1 
ATOM 5520 C C   . PRO E 5 32  ? 262.245 346.629 421.570 1.00 101.15 ? 32  PRO C C   1 
ATOM 5521 O O   . PRO E 5 32  ? 262.150 347.347 422.567 1.00 101.15 ? 32  PRO C O   1 
ATOM 5522 C CB  . PRO E 5 32  ? 261.121 346.843 419.330 1.00 101.15 ? 32  PRO C CB  1 
ATOM 5523 C CG  . PRO E 5 32  ? 260.405 348.129 419.409 1.00 101.15 ? 32  PRO C CG  1 
ATOM 5524 C CD  . PRO E 5 32  ? 259.259 347.900 420.344 1.00 101.15 ? 32  PRO C CD  1 
ATOM 5525 N N   . GLU E 5 33  ? 263.406 346.136 421.151 1.00 102.68 ? 33  GLU C N   1 
ATOM 5526 C CA  . GLU E 5 33  ? 264.616 346.245 421.948 1.00 102.68 ? 33  GLU C CA  1 
ATOM 5527 C C   . GLU E 5 33  ? 265.307 347.589 421.741 1.00 102.68 ? 33  GLU C C   1 
ATOM 5528 O O   . GLU E 5 33  ? 264.906 348.414 420.918 1.00 102.68 ? 33  GLU C O   1 
ATOM 5529 C CB  . GLU E 5 33  ? 265.587 345.119 421.605 1.00 102.68 ? 33  GLU C CB  1 
ATOM 5530 C CG  . GLU E 5 33  ? 265.168 343.706 422.009 1.00 102.68 ? 33  GLU C CG  1 
ATOM 5531 C CD  . GLU E 5 33  ? 265.197 343.403 423.507 1.00 102.68 ? 33  GLU C CD  1 
ATOM 5532 O OE1 . GLU E 5 33  ? 265.170 342.200 423.836 1.00 102.68 ? 33  GLU C OE1 1 
ATOM 5533 O OE2 . GLU E 5 33  ? 265.274 344.309 424.362 1.00 102.68 ? 33  GLU C OE2 1 
ATOM 5534 N N   . MET E 5 34  ? 266.375 347.789 422.507 1.00 102.44 ? 34  MET C N   1 
ATOM 5535 C CA  . MET E 5 34  ? 267.224 348.965 422.410 1.00 102.44 ? 34  MET C CA  1 
ATOM 5536 C C   . MET E 5 34  ? 268.590 348.583 422.953 1.00 102.44 ? 34  MET C C   1 
ATOM 5537 O O   . MET E 5 34  ? 268.675 347.920 423.989 1.00 102.44 ? 34  MET C O   1 
ATOM 5538 C CB  . MET E 5 34  ? 266.627 350.141 423.193 1.00 102.44 ? 34  MET C CB  1 
ATOM 5539 C CG  . MET E 5 34  ? 267.511 351.368 423.285 1.00 102.44 ? 34  MET C CG  1 
ATOM 5540 S SD  . MET E 5 34  ? 267.149 352.360 424.741 1.00 102.44 ? 34  MET C SD  1 
ATOM 5541 C CE  . MET E 5 34  ? 268.562 353.456 424.754 1.00 102.44 ? 34  MET C CE  1 
ATOM 5542 N N   . GLN E 5 35  ? 269.649 348.986 422.259 1.00 98.86  ? 35  GLN C N   1 
ATOM 5543 C CA  . GLN E 5 35  ? 271.003 348.556 422.596 1.00 98.86  ? 35  GLN C CA  1 
ATOM 5544 C C   . GLN E 5 35  ? 271.480 349.276 423.848 1.00 98.86  ? 35  GLN C C   1 
ATOM 5545 O O   . GLN E 5 35  ? 272.042 350.369 423.777 1.00 98.86  ? 35  GLN C O   1 
ATOM 5546 C CB  . GLN E 5 35  ? 271.941 348.819 421.425 1.00 98.86  ? 35  GLN C CB  1 
ATOM 5547 C CG  . GLN E 5 35  ? 271.836 347.867 420.219 1.00 98.86  ? 35  GLN C CG  1 
ATOM 5548 C CD  . GLN E 5 35  ? 272.352 346.437 420.443 1.00 98.86  ? 35  GLN C CD  1 
ATOM 5549 O OE1 . GLN E 5 35  ? 272.105 345.797 421.465 1.00 98.86  ? 35  GLN C OE1 1 
ATOM 5550 N NE2 . GLN E 5 35  ? 273.085 345.938 419.459 1.00 98.86  ? 35  GLN C NE2 1 
ATOM 5551 N N   . ILE E 5 36  ? 271.275 348.653 425.002 1.00 91.21  ? 36  ILE C N   1 
ATOM 5552 C CA  . ILE E 5 36  ? 271.701 349.198 426.286 1.00 91.21  ? 36  ILE C CA  1 
ATOM 5553 C C   . ILE E 5 36  ? 273.076 348.621 426.594 1.00 91.21  ? 36  ILE C C   1 
ATOM 5554 O O   . ILE E 5 36  ? 273.274 347.408 426.448 1.00 91.21  ? 36  ILE C O   1 
ATOM 5555 C CB  . ILE E 5 36  ? 270.677 348.869 427.379 1.00 91.21  ? 36  ILE C CB  1 
ATOM 5556 C CG1 . ILE E 5 36  ? 269.376 349.611 427.109 1.00 91.21  ? 36  ILE C CG1 1 
ATOM 5557 C CG2 . ILE E 5 36  ? 271.195 349.218 428.749 1.00 91.21  ? 36  ILE C CG2 1 
ATOM 5558 C CD1 . ILE E 5 36  ? 268.293 349.293 428.095 1.00 91.21  ? 36  ILE C CD1 1 
ATOM 5559 N N   . PRO E 5 37  ? 274.054 349.433 426.988 1.00 89.59  ? 37  PRO C N   1 
ATOM 5560 C CA  . PRO E 5 37  ? 275.406 348.912 427.194 1.00 89.59  ? 37  PRO C CA  1 
ATOM 5561 C C   . PRO E 5 37  ? 275.516 348.072 428.450 1.00 89.59  ? 37  PRO C C   1 
ATOM 5562 O O   . PRO E 5 37  ? 274.823 348.299 429.441 1.00 89.59  ? 37  PRO C O   1 
ATOM 5563 C CB  . PRO E 5 37  ? 276.256 350.180 427.319 1.00 89.59  ? 37  PRO C CB  1 
ATOM 5564 C CG  . PRO E 5 37  ? 275.418 351.266 426.790 1.00 89.59  ? 37  PRO C CG  1 
ATOM 5565 C CD  . PRO E 5 37  ? 274.023 350.895 427.100 1.00 89.59  ? 37  PRO C CD  1 
ATOM 5566 N N   . GLY E 5 38  ? 276.408 347.093 428.397 1.00 84.03  ? 38  GLY C N   1 
ATOM 5567 C CA  . GLY E 5 38  ? 276.728 346.309 429.569 1.00 84.03  ? 38  GLY C CA  1 
ATOM 5568 C C   . GLY E 5 38  ? 275.802 345.142 429.805 1.00 84.03  ? 38  GLY C C   1 
ATOM 5569 O O   . GLY E 5 38  ? 275.179 345.048 430.864 1.00 84.03  ? 38  GLY C O   1 
ATOM 5570 N N   . ARG E 5 39  ? 275.702 344.243 428.833 1.00 86.38  ? 39  ARG C N   1 
ATOM 5571 C CA  . ARG E 5 39  ? 274.844 343.076 428.952 1.00 86.38  ? 39  ARG C CA  1 
ATOM 5572 C C   . ARG E 5 39  ? 275.611 341.931 429.593 1.00 86.38  ? 39  ARG C C   1 
ATOM 5573 O O   . ARG E 5 39  ? 276.752 341.658 429.218 1.00 86.38  ? 39  ARG C O   1 
ATOM 5574 C CB  . ARG E 5 39  ? 274.320 342.652 427.586 1.00 86.38  ? 39  ARG C CB  1 
ATOM 5575 C CG  . ARG E 5 39  ? 273.359 341.499 427.651 1.00 86.38  ? 39  ARG C CG  1 
ATOM 5576 C CD  . ARG E 5 39  ? 272.752 341.222 426.310 1.00 86.38  ? 39  ARG C CD  1 
ATOM 5577 N NE  . ARG E 5 39  ? 271.805 340.122 426.381 1.00 86.38  ? 39  ARG C NE  1 
ATOM 5578 C CZ  . ARG E 5 39  ? 271.001 339.780 425.386 1.00 86.38  ? 39  ARG C CZ  1 
ATOM 5579 N NH1 . ARG E 5 39  ? 270.166 338.766 425.528 1.00 86.38  ? 39  ARG C NH1 1 
ATOM 5580 N NH2 . ARG E 5 39  ? 271.033 340.455 424.249 1.00 86.38  ? 39  ARG C NH2 1 
ATOM 5581 N N   . VAL E 5 40  ? 274.982 341.263 430.550 1.00 87.77  ? 40  VAL C N   1 
ATOM 5582 C CA  . VAL E 5 40  ? 275.585 340.144 431.259 1.00 87.77  ? 40  VAL C CA  1 
ATOM 5583 C C   . VAL E 5 40  ? 274.997 338.861 430.693 1.00 87.77  ? 40  VAL C C   1 
ATOM 5584 O O   . VAL E 5 40  ? 273.784 338.649 430.746 1.00 87.77  ? 40  VAL C O   1 
ATOM 5585 C CB  . VAL E 5 40  ? 275.347 340.247 432.766 1.00 87.77  ? 40  VAL C CB  1 
ATOM 5586 C CG1 . VAL E 5 40  ? 275.728 338.966 433.440 1.00 87.77  ? 40  VAL C CG1 1 
ATOM 5587 C CG2 . VAL E 5 40  ? 276.156 341.376 433.327 1.00 87.77  ? 40  VAL C CG2 1 
ATOM 5588 N N   . ASN E 5 41  ? 275.851 338.003 430.142 1.00 93.38  ? 41  ASN C N   1 
ATOM 5589 C CA  . ASN E 5 41  ? 275.407 336.717 429.627 1.00 93.38  ? 41  ASN C CA  1 
ATOM 5590 C C   . ASN E 5 41  ? 275.639 335.577 430.598 1.00 93.38  ? 41  ASN C C   1 
ATOM 5591 O O   . ASN E 5 41  ? 274.976 334.544 430.483 1.00 93.38  ? 41  ASN C O   1 
ATOM 5592 C CB  . ASN E 5 41  ? 276.124 336.381 428.322 1.00 93.38  ? 41  ASN C CB  1 
ATOM 5593 C CG  . ASN E 5 41  ? 275.741 337.299 427.197 1.00 93.38  ? 41  ASN C CG  1 
ATOM 5594 O OD1 . ASN E 5 41  ? 274.736 337.086 426.526 1.00 93.38  ? 41  ASN C OD1 1 
ATOM 5595 N ND2 . ASN E 5 41  ? 276.546 338.326 426.975 1.00 93.38  ? 41  ASN C ND2 1 
ATOM 5596 N N   . ASN E 5 42  ? 276.564 335.733 431.537 1.00 94.28  ? 42  ASN C N   1 
ATOM 5597 C CA  . ASN E 5 42  ? 276.951 334.648 432.422 1.00 94.28  ? 42  ASN C CA  1 
ATOM 5598 C C   . ASN E 5 42  ? 277.406 335.237 433.742 1.00 94.28  ? 42  ASN C C   1 
ATOM 5599 O O   . ASN E 5 42  ? 278.062 336.277 433.762 1.00 94.28  ? 42  ASN C O   1 
ATOM 5600 C CB  . ASN E 5 42  ? 278.071 333.815 431.807 1.00 94.28  ? 42  ASN C CB  1 
ATOM 5601 C CG  . ASN E 5 42  ? 278.064 332.395 432.293 1.00 94.28  ? 42  ASN C CG  1 
ATOM 5602 O OD1 . ASN E 5 42  ? 278.025 332.142 433.490 1.00 94.28  ? 42  ASN C OD1 1 
ATOM 5603 N ND2 . ASN E 5 42  ? 278.102 331.453 431.363 1.00 94.28  ? 42  ASN C ND2 1 
ATOM 5604 N N   . LEU E 5 43  ? 277.076 334.562 434.842 1.00 93.78  ? 43  LEU C N   1 
ATOM 5605 C CA  . LEU E 5 43  ? 277.381 335.115 436.153 1.00 93.78  ? 43  LEU C CA  1 
ATOM 5606 C C   . LEU E 5 43  ? 278.845 335.010 436.532 1.00 93.78  ? 43  LEU C C   1 
ATOM 5607 O O   . LEU E 5 43  ? 279.227 335.566 437.563 1.00 93.78  ? 43  LEU C O   1 
ATOM 5608 C CB  . LEU E 5 43  ? 276.563 334.438 437.240 1.00 93.78  ? 43  LEU C CB  1 
ATOM 5609 C CG  . LEU E 5 43  ? 275.176 334.995 437.508 1.00 93.78  ? 43  LEU C CG  1 
ATOM 5610 C CD1 . LEU E 5 43  ? 274.744 334.537 438.870 1.00 93.78  ? 43  LEU C CD1 1 
ATOM 5611 C CD2 . LEU E 5 43  ? 275.163 336.498 437.433 1.00 93.78  ? 43  LEU C CD2 1 
ATOM 5612 N N   . MET E 5 44  ? 279.665 334.304 435.765 1.00 98.32  ? 44  MET C N   1 
ATOM 5613 C CA  . MET E 5 44  ? 281.090 334.342 436.048 1.00 98.32  ? 44  MET C CA  1 
ATOM 5614 C C   . MET E 5 44  ? 281.692 335.686 435.684 1.00 98.32  ? 44  MET C C   1 
ATOM 5615 O O   . MET E 5 44  ? 282.672 336.103 436.304 1.00 98.32  ? 44  MET C O   1 
ATOM 5616 C CB  . MET E 5 44  ? 281.810 333.214 435.323 1.00 98.32  ? 44  MET C CB  1 
ATOM 5617 C CG  . MET E 5 44  ? 281.604 331.850 435.944 1.00 98.32  ? 44  MET C CG  1 
ATOM 5618 S SD  . MET E 5 44  ? 282.353 331.729 437.579 1.00 98.32  ? 44  MET C SD  1 
ATOM 5619 C CE  . MET E 5 44  ? 280.923 331.733 438.653 1.00 98.32  ? 44  MET C CE  1 
ATOM 5620 N N   . GLU E 5 45  ? 281.091 336.403 434.734 1.00 99.48  ? 45  GLU C N   1 
ATOM 5621 C CA  . GLU E 5 45  ? 281.628 337.690 434.310 1.00 99.48  ? 45  GLU C CA  1 
ATOM 5622 C C   . GLU E 5 45  ? 281.455 338.774 435.360 1.00 99.48  ? 45  GLU C C   1 
ATOM 5623 O O   . GLU E 5 45  ? 282.065 339.838 435.237 1.00 99.48  ? 45  GLU C O   1 
ATOM 5624 C CB  . GLU E 5 45  ? 280.972 338.131 433.003 1.00 99.48  ? 45  GLU C CB  1 
ATOM 5625 C CG  . GLU E 5 45  ? 280.915 337.059 431.912 1.00 99.48  ? 45  GLU C CG  1 
ATOM 5626 C CD  . GLU E 5 45  ? 282.204 336.256 431.733 1.00 99.48  ? 45  GLU C CD  1 
ATOM 5627 O OE1 . GLU E 5 45  ? 282.102 335.026 431.547 1.00 99.48  ? 45  GLU C OE1 1 
ATOM 5628 O OE2 . GLU E 5 45  ? 283.307 336.845 431.693 1.00 99.48  ? 45  GLU C OE2 1 
ATOM 5629 N N   . ILE E 5 46  ? 280.623 338.546 436.372 1.00 93.49  ? 46  ILE C N   1 
ATOM 5630 C CA  . ILE E 5 46  ? 280.641 339.419 437.535 1.00 93.49  ? 46  ILE C CA  1 
ATOM 5631 C C   . ILE E 5 46  ? 281.854 339.121 438.401 1.00 93.49  ? 46  ILE C C   1 
ATOM 5632 O O   . ILE E 5 46  ? 282.542 340.036 438.860 1.00 93.49  ? 46  ILE C O   1 
ATOM 5633 C CB  . ILE E 5 46  ? 279.327 339.280 438.320 1.00 93.49  ? 46  ILE C CB  1 
ATOM 5634 C CG1 . ILE E 5 46  ? 278.161 339.760 437.465 1.00 93.49  ? 46  ILE C CG1 1 
ATOM 5635 C CG2 . ILE E 5 46  ? 279.384 340.057 439.616 1.00 93.49  ? 46  ILE C CG2 1 
ATOM 5636 C CD1 . ILE E 5 46  ? 276.846 339.800 438.192 1.00 93.49  ? 46  ILE C CD1 1 
ATOM 5637 N N   . ALA E 5 47  ? 282.178 337.845 438.589 1.00 94.41  ? 47  ALA C N   1 
ATOM 5638 C CA  . ALA E 5 47  ? 283.253 337.469 439.496 1.00 94.41  ? 47  ALA C CA  1 
ATOM 5639 C C   . ALA E 5 47  ? 284.646 337.696 438.927 1.00 94.41  ? 47  ALA C C   1 
ATOM 5640 O O   . ALA E 5 47  ? 285.617 337.557 439.673 1.00 94.41  ? 47  ALA C O   1 
ATOM 5641 C CB  . ALA E 5 47  ? 283.115 336.003 439.899 1.00 94.41  ? 47  ALA C CB  1 
ATOM 5642 N N   . GLU E 5 48  ? 284.786 338.031 437.646 1.00 97.83  ? 48  GLU C N   1 
ATOM 5643 C CA  . GLU E 5 48  ? 286.122 338.239 437.099 1.00 97.83  ? 48  GLU C CA  1 
ATOM 5644 C C   . GLU E 5 48  ? 286.746 339.555 437.519 1.00 97.83  ? 48  GLU C C   1 
ATOM 5645 O O   . GLU E 5 48  ? 287.965 339.707 437.401 1.00 97.83  ? 48  GLU C O   1 
ATOM 5646 C CB  . GLU E 5 48  ? 286.118 338.187 435.569 1.00 97.83  ? 48  GLU C CB  1 
ATOM 5647 C CG  . GLU E 5 48  ? 285.416 337.004 434.903 1.00 97.83  ? 48  GLU C CG  1 
ATOM 5648 C CD  . GLU E 5 48  ? 286.058 335.629 435.106 1.00 97.83  ? 48  GLU C CD  1 
ATOM 5649 O OE1 . GLU E 5 48  ? 287.051 335.475 435.837 1.00 97.83  ? 48  GLU C OE1 1 
ATOM 5650 O OE2 . GLU E 5 48  ? 285.545 334.666 434.507 1.00 97.83  ? 48  GLU C OE2 1 
ATOM 5651 N N   . VAL E 5 49  ? 285.954 340.514 437.985 1.00 92.47  ? 49  VAL C N   1 
ATOM 5652 C CA  . VAL E 5 49  ? 286.507 341.801 438.384 1.00 92.47  ? 49  VAL C CA  1 
ATOM 5653 C C   . VAL E 5 49  ? 287.124 341.655 439.766 1.00 92.47  ? 49  VAL C C   1 
ATOM 5654 O O   . VAL E 5 49  ? 286.863 340.679 440.475 1.00 92.47  ? 49  VAL C O   1 
ATOM 5655 C CB  . VAL E 5 49  ? 285.440 342.904 438.358 1.00 92.47  ? 49  VAL C CB  1 
ATOM 5656 C CG1 . VAL E 5 49  ? 284.697 342.868 437.047 1.00 92.47  ? 49  VAL C CG1 1 
ATOM 5657 C CG2 . VAL E 5 49  ? 284.489 342.739 439.500 1.00 92.47  ? 49  VAL C CG2 1 
ATOM 5658 N N   . ASP E 5 50  ? 287.949 342.614 440.153 1.00 88.62  ? 50  ASP C N   1 
ATOM 5659 C CA  . ASP E 5 50  ? 288.701 342.524 441.391 1.00 88.62  ? 50  ASP C CA  1 
ATOM 5660 C C   . ASP E 5 50  ? 288.040 343.325 442.504 1.00 88.62  ? 50  ASP C C   1 
ATOM 5661 O O   . ASP E 5 50  ? 287.465 344.388 442.276 1.00 88.62  ? 50  ASP C O   1 
ATOM 5662 C CB  . ASP E 5 50  ? 290.141 342.983 441.176 1.00 88.62  ? 50  ASP C CB  1 
ATOM 5663 C CG  . ASP E 5 50  ? 290.227 344.312 440.473 1.00 88.62  ? 50  ASP C CG  1 
ATOM 5664 O OD1 . ASP E 5 50  ? 289.182 344.817 440.022 1.00 88.62  ? 50  ASP C OD1 1 
ATOM 5665 O OD2 . ASP E 5 50  ? 291.344 344.854 440.369 1.00 88.62  ? 50  ASP C OD2 1 
ATOM 5666 N N   . SER E 5 51  ? 288.120 342.793 443.717 1.00 79.24  ? 51  SER C N   1 
ATOM 5667 C CA  . SER E 5 51  ? 287.441 343.380 444.856 1.00 79.24  ? 51  SER C CA  1 
ATOM 5668 C C   . SER E 5 51  ? 288.393 343.421 446.033 1.00 79.24  ? 51  SER C C   1 
ATOM 5669 O O   . SER E 5 51  ? 289.263 342.563 446.172 1.00 79.24  ? 51  SER C O   1 
ATOM 5670 C CB  . SER E 5 51  ? 286.213 342.574 445.213 1.00 79.24  ? 51  SER C CB  1 
ATOM 5671 O OG  . SER E 5 51  ? 285.587 342.145 444.027 1.00 79.24  ? 51  SER C OG  1 
ATOM 5672 N N   . VAL E 5 52  ? 288.222 344.413 446.879 1.00 75.60  ? 52  VAL C N   1 
ATOM 5673 C CA  . VAL E 5 52  ? 289.104 344.582 448.022 1.00 75.60  ? 52  VAL C CA  1 
ATOM 5674 C C   . VAL E 5 52  ? 288.693 343.592 449.099 1.00 75.60  ? 52  VAL C C   1 
ATOM 5675 O O   . VAL E 5 52  ? 287.504 343.331 449.295 1.00 75.60  ? 52  VAL C O   1 
ATOM 5676 C CB  . VAL E 5 52  ? 289.042 346.032 448.519 1.00 75.60  ? 52  VAL C CB  1 
ATOM 5677 C CG1 . VAL E 5 52  ? 290.206 346.329 449.408 1.00 75.60  ? 52  VAL C CG1 1 
ATOM 5678 C CG2 . VAL E 5 52  ? 289.024 346.973 447.351 1.00 75.60  ? 52  VAL C CG2 1 
ATOM 5679 N N   . VAL E 5 53  ? 289.666 343.017 449.787 1.00 75.80  ? 53  VAL C N   1 
ATOM 5680 C CA  . VAL E 5 53  ? 289.431 341.958 450.765 1.00 75.80  ? 53  VAL C CA  1 
ATOM 5681 C C   . VAL E 5 53  ? 289.549 342.554 452.159 1.00 75.80  ? 53  VAL C C   1 
ATOM 5682 O O   . VAL E 5 53  ? 290.591 343.128 452.486 1.00 75.80  ? 53  VAL C O   1 
ATOM 5683 C CB  . VAL E 5 53  ? 290.423 340.798 450.590 1.00 75.80  ? 53  VAL C CB  1 
ATOM 5684 C CG1 . VAL E 5 53  ? 290.327 339.847 451.744 1.00 75.80  ? 53  VAL C CG1 1 
ATOM 5685 C CG2 . VAL E 5 53  ? 290.128 340.076 449.326 1.00 75.80  ? 53  VAL C CG2 1 
ATOM 5686 N N   . PRO E 5 54  ? 288.534 342.437 453.002 1.00 80.80  ? 54  PRO C N   1 
ATOM 5687 C CA  . PRO E 5 54  ? 288.637 342.920 454.387 1.00 80.80  ? 54  PRO C CA  1 
ATOM 5688 C C   . PRO E 5 54  ? 289.495 341.994 455.241 1.00 80.80  ? 54  PRO C C   1 
ATOM 5689 O O   . PRO E 5 54  ? 289.029 341.131 455.969 1.00 80.80  ? 54  PRO C O   1 
ATOM 5690 C CB  . PRO E 5 54  ? 287.179 342.939 454.842 1.00 80.80  ? 54  PRO C CB  1 
ATOM 5691 C CG  . PRO E 5 54  ? 286.525 341.918 454.026 1.00 80.80  ? 54  PRO C CG  1 
ATOM 5692 C CD  . PRO E 5 54  ? 287.189 341.938 452.696 1.00 80.80  ? 54  PRO C CD  1 
ATOM 5693 N N   . VAL E 5 55  ? 290.805 342.191 455.167 1.00 81.75  ? 55  VAL C N   1 
ATOM 5694 C CA  . VAL E 5 55  ? 291.754 341.238 455.724 1.00 81.75  ? 55  VAL C CA  1 
ATOM 5695 C C   . VAL E 5 55  ? 292.232 341.748 457.082 1.00 81.75  ? 55  VAL C C   1 
ATOM 5696 O O   . VAL E 5 55  ? 293.171 341.215 457.682 1.00 81.75  ? 55  VAL C O   1 
ATOM 5697 C CB  . VAL E 5 55  ? 292.898 341.017 454.715 1.00 81.75  ? 55  VAL C CB  1 
ATOM 5698 C CG1 . VAL E 5 55  ? 293.800 342.204 454.660 1.00 81.75  ? 55  VAL C CG1 1 
ATOM 5699 C CG2 . VAL E 5 55  ? 293.648 339.715 454.934 1.00 81.75  ? 55  VAL C CG2 1 
ATOM 5700 N N   . ASN E 5 56  ? 291.556 342.756 457.609 1.00 85.83  ? 56  ASN C N   1 
ATOM 5701 C CA  . ASN E 5 56  ? 291.944 343.366 458.872 1.00 85.83  ? 56  ASN C CA  1 
ATOM 5702 C C   . ASN E 5 56  ? 290.736 343.560 459.774 1.00 85.83  ? 56  ASN C C   1 
ATOM 5703 O O   . ASN E 5 56  ? 290.467 344.664 460.243 1.00 85.83  ? 56  ASN C O   1 
ATOM 5704 C CB  . ASN E 5 56  ? 292.652 344.688 458.634 1.00 85.83  ? 56  ASN C CB  1 
ATOM 5705 C CG  . ASN E 5 56  ? 293.444 345.138 459.828 1.00 85.83  ? 56  ASN C CG  1 
ATOM 5706 O OD1 . ASN E 5 56  ? 293.720 344.352 460.725 1.00 85.83  ? 56  ASN C OD1 1 
ATOM 5707 N ND2 . ASN E 5 56  ? 293.798 346.411 459.861 1.00 85.83  ? 56  ASN C ND2 1 
ATOM 5708 N N   . ASN E 5 57  ? 289.962 342.494 459.993 1.00 89.16  ? 57  ASN C N   1 
ATOM 5709 C CA  . ASN E 5 57  ? 288.700 342.584 460.722 1.00 89.16  ? 57  ASN C CA  1 
ATOM 5710 C C   . ASN E 5 57  ? 288.844 343.053 462.165 1.00 89.16  ? 57  ASN C C   1 
ATOM 5711 O O   . ASN E 5 57  ? 288.410 344.157 462.496 1.00 89.16  ? 57  ASN C O   1 
ATOM 5712 C CB  . ASN E 5 57  ? 288.003 341.233 460.712 1.00 89.16  ? 57  ASN C CB  1 
ATOM 5713 C CG  . ASN E 5 57  ? 287.914 340.651 459.343 1.00 89.16  ? 57  ASN C CG  1 
ATOM 5714 O OD1 . ASN E 5 57  ? 288.238 339.489 459.128 1.00 89.16  ? 57  ASN C OD1 1 
ATOM 5715 N ND2 . ASN E 5 57  ? 287.477 341.455 458.396 1.00 89.16  ? 57  ASN C ND2 1 
ATOM 5716 N N   . THR E 5 58  ? 289.481 342.232 463.008 1.00 99.13  ? 58  THR C N   1 
ATOM 5717 C CA  . THR E 5 58  ? 289.832 342.425 464.423 1.00 99.13  ? 58  THR C CA  1 
ATOM 5718 C C   . THR E 5 58  ? 288.853 343.222 465.288 1.00 99.13  ? 58  THR C C   1 
ATOM 5719 O O   . THR E 5 58  ? 289.274 343.999 466.152 1.00 99.13  ? 58  THR C O   1 
ATOM 5720 C CB  . THR E 5 58  ? 291.248 343.023 464.578 1.00 99.13  ? 58  THR C CB  1 
ATOM 5721 O OG1 . THR E 5 58  ? 291.507 343.260 465.965 1.00 99.13  ? 58  THR C OG1 1 
ATOM 5722 C CG2 . THR E 5 58  ? 291.484 344.333 463.816 1.00 99.13  ? 58  THR C CG2 1 
ATOM 5723 N N   . GLU E 5 59  ? 287.548 343.061 465.044 1.00 104.47 ? 59  GLU C N   1 
ATOM 5724 C CA  . GLU E 5 59  ? 286.444 343.337 465.970 1.00 104.47 ? 59  GLU C CA  1 
ATOM 5725 C C   . GLU E 5 59  ? 286.192 344.823 466.244 1.00 104.47 ? 59  GLU C C   1 
ATOM 5726 O O   . GLU E 5 59  ? 285.119 345.201 466.724 1.00 104.47 ? 59  GLU C O   1 
ATOM 5727 C CB  . GLU E 5 59  ? 286.679 342.531 467.271 1.00 104.47 ? 59  GLU C CB  1 
ATOM 5728 C CG  . GLU E 5 59  ? 285.737 342.693 468.501 1.00 104.47 ? 59  GLU C CG  1 
ATOM 5729 C CD  . GLU E 5 59  ? 284.235 342.460 468.251 1.00 104.47 ? 59  GLU C CD  1 
ATOM 5730 O OE1 . GLU E 5 59  ? 283.807 342.038 467.156 1.00 104.47 ? 59  GLU C OE1 1 
ATOM 5731 O OE2 . GLU E 5 59  ? 283.453 342.711 469.191 1.00 104.47 ? 59  GLU C OE2 1 
ATOM 5732 N N   . ASP E 5 60  ? 287.094 345.690 465.824 1.00 100.62 ? 60  ASP C N   1 
ATOM 5733 C CA  . ASP E 5 60  ? 286.890 347.114 465.999 1.00 100.62 ? 60  ASP C CA  1 
ATOM 5734 C C   . ASP E 5 60  ? 287.142 347.909 464.731 1.00 100.62 ? 60  ASP C C   1 
ATOM 5735 O O   . ASP E 5 60  ? 286.940 349.125 464.735 1.00 100.62 ? 60  ASP C O   1 
ATOM 5736 C CB  . ASP E 5 60  ? 287.764 347.639 467.149 1.00 100.62 ? 60  ASP C CB  1 
ATOM 5737 C CG  . ASP E 5 60  ? 289.202 347.154 467.073 1.00 100.62 ? 60  ASP C CG  1 
ATOM 5738 O OD1 . ASP E 5 60  ? 289.764 347.026 465.970 1.00 100.62 ? 60  ASP C OD1 1 
ATOM 5739 O OD2 . ASP E 5 60  ? 289.781 346.883 468.144 1.00 100.62 ? 60  ASP C OD2 1 
ATOM 5740 N N   . ASN E 5 61  ? 287.573 347.263 463.659 1.00 93.94  ? 61  ASN C N   1 
ATOM 5741 C CA  . ASN E 5 61  ? 287.704 347.898 462.365 1.00 93.94  ? 61  ASN C CA  1 
ATOM 5742 C C   . ASN E 5 61  ? 286.618 347.470 461.400 1.00 93.94  ? 61  ASN C C   1 
ATOM 5743 O O   . ASN E 5 61  ? 286.650 347.883 460.242 1.00 93.94  ? 61  ASN C O   1 
ATOM 5744 C CB  . ASN E 5 61  ? 289.066 347.583 461.763 1.00 93.94  ? 61  ASN C CB  1 
ATOM 5745 C CG  . ASN E 5 61  ? 290.188 347.949 462.677 1.00 93.94  ? 61  ASN C CG  1 
ATOM 5746 O OD1 . ASN E 5 61  ? 289.993 348.684 463.637 1.00 93.94  ? 61  ASN C OD1 1 
ATOM 5747 N ND2 . ASN E 5 61  ? 291.379 347.444 462.391 1.00 93.94  ? 61  ASN C ND2 1 
ATOM 5748 N N   . VAL E 5 62  ? 285.664 346.654 461.841 1.00 92.08  ? 62  VAL C N   1 
ATOM 5749 C CA  . VAL E 5 62  ? 284.653 346.177 460.908 1.00 92.08  ? 62  VAL C CA  1 
ATOM 5750 C C   . VAL E 5 62  ? 283.644 347.267 460.585 1.00 92.08  ? 62  VAL C C   1 
ATOM 5751 O O   . VAL E 5 62  ? 283.058 347.267 459.499 1.00 92.08  ? 62  VAL C O   1 
ATOM 5752 C CB  . VAL E 5 62  ? 283.971 344.918 461.457 1.00 92.08  ? 62  VAL C CB  1 
ATOM 5753 C CG1 . VAL E 5 62  ? 284.943 343.778 461.447 1.00 92.08  ? 62  VAL C CG1 1 
ATOM 5754 C CG2 . VAL E 5 62  ? 283.490 345.150 462.863 1.00 92.08  ? 62  VAL C CG2 1 
ATOM 5755 N N   . SER E 5 63  ? 283.410 348.196 461.498 1.00 92.64  ? 63  SER C N   1 
ATOM 5756 C CA  . SER E 5 63  ? 282.552 349.343 461.216 1.00 92.64  ? 63  SER C CA  1 
ATOM 5757 C C   . SER E 5 63  ? 283.372 350.557 460.812 1.00 92.64  ? 63  SER C C   1 
ATOM 5758 O O   . SER E 5 63  ? 283.192 351.637 461.366 1.00 92.64  ? 63  SER C O   1 
ATOM 5759 C CB  . SER E 5 63  ? 281.688 349.658 462.425 1.00 92.64  ? 63  SER C CB  1 
ATOM 5760 O OG  . SER E 5 63  ? 282.436 350.372 463.388 1.00 92.64  ? 63  SER C OG  1 
ATOM 5761 N N   . SER E 5 64  ? 284.263 350.398 459.837 1.00 87.55  ? 64  SER C N   1 
ATOM 5762 C CA  . SER E 5 64  ? 285.109 351.486 459.367 1.00 87.55  ? 64  SER C CA  1 
ATOM 5763 C C   . SER E 5 64  ? 285.705 351.092 458.027 1.00 87.55  ? 64  SER C C   1 
ATOM 5764 O O   . SER E 5 64  ? 285.388 350.040 457.468 1.00 87.55  ? 64  SER C O   1 
ATOM 5765 C CB  . SER E 5 64  ? 286.225 351.812 460.356 1.00 87.55  ? 64  SER C CB  1 
ATOM 5766 O OG  . SER E 5 64  ? 287.271 352.510 459.712 1.00 87.55  ? 64  SER C OG  1 
ATOM 5767 N N   . LEU E 5 65  ? 286.581 351.947 457.517 1.00 83.07  ? 65  LEU C N   1 
ATOM 5768 C CA  . LEU E 5 65  ? 287.363 351.641 456.333 1.00 83.07  ? 65  LEU C CA  1 
ATOM 5769 C C   . LEU E 5 65  ? 288.747 351.124 456.666 1.00 83.07  ? 65  LEU C C   1 
ATOM 5770 O O   . LEU E 5 65  ? 289.551 350.931 455.754 1.00 83.07  ? 65  LEU C O   1 
ATOM 5771 C CB  . LEU E 5 65  ? 287.493 352.870 455.445 1.00 83.07  ? 65  LEU C CB  1 
ATOM 5772 C CG  . LEU E 5 65  ? 286.330 353.054 454.493 1.00 83.07  ? 65  LEU C CG  1 
ATOM 5773 C CD1 . LEU E 5 65  ? 286.479 354.355 453.749 1.00 83.07  ? 65  LEU C CD1 1 
ATOM 5774 C CD2 . LEU E 5 65  ? 286.297 351.892 453.547 1.00 83.07  ? 65  LEU C CD2 1 
ATOM 5775 N N   . LYS E 5 66  ? 289.051 350.912 457.940 1.00 86.79  ? 66  LYS C N   1 
ATOM 5776 C CA  . LYS E 5 66  ? 290.310 350.283 458.308 1.00 86.79  ? 66  LYS C CA  1 
ATOM 5777 C C   . LYS E 5 66  ? 290.227 348.762 458.242 1.00 86.79  ? 66  LYS C C   1 
ATOM 5778 O O   . LYS E 5 66  ? 291.215 348.077 458.513 1.00 86.79  ? 66  LYS C O   1 
ATOM 5779 C CB  . LYS E 5 66  ? 290.741 350.771 459.696 1.00 86.79  ? 66  LYS C CB  1 
ATOM 5780 C CG  . LYS E 5 66  ? 292.239 350.669 459.970 1.00 86.79  ? 66  LYS C CG  1 
ATOM 5781 C CD  . LYS E 5 66  ? 292.689 351.525 461.111 1.00 86.79  ? 66  LYS C CD  1 
ATOM 5782 C CE  . LYS E 5 66  ? 293.129 352.865 460.582 1.00 86.79  ? 66  LYS C CE  1 
ATOM 5783 N NZ  . LYS E 5 66  ? 294.361 352.735 459.762 1.00 86.79  ? 66  LYS C NZ  1 
ATOM 5784 N N   . ALA E 5 67  ? 289.084 348.210 457.844 1.00 82.88  ? 67  ALA C N   1 
ATOM 5785 C CA  . ALA E 5 67  ? 289.015 346.774 457.630 1.00 82.88  ? 67  ALA C CA  1 
ATOM 5786 C C   . ALA E 5 67  ? 289.801 346.348 456.402 1.00 82.88  ? 67  ALA C C   1 
ATOM 5787 O O   . ALA E 5 67  ? 290.174 345.178 456.289 1.00 82.88  ? 67  ALA C O   1 
ATOM 5788 C CB  . ALA E 5 67  ? 287.566 346.329 457.496 1.00 82.88  ? 67  ALA C CB  1 
ATOM 5789 N N   . TYR E 5 68  ? 290.076 347.266 455.483 1.00 80.16  ? 68  TYR C N   1 
ATOM 5790 C CA  . TYR E 5 68  ? 290.720 346.910 454.231 1.00 80.16  ? 68  TYR C CA  1 
ATOM 5791 C C   . TYR E 5 68  ? 292.221 347.152 454.216 1.00 80.16  ? 68  TYR C C   1 
ATOM 5792 O O   . TYR E 5 68  ? 292.885 346.712 453.278 1.00 80.16  ? 68  TYR C O   1 
ATOM 5793 C CB  . TYR E 5 68  ? 290.078 347.678 453.080 1.00 80.16  ? 68  TYR C CB  1 
ATOM 5794 C CG  . TYR E 5 68  ? 288.604 347.421 452.945 1.00 80.16  ? 68  TYR C CG  1 
ATOM 5795 C CD1 . TYR E 5 68  ? 288.141 346.267 452.352 1.00 80.16  ? 68  TYR C CD1 1 
ATOM 5796 C CD2 . TYR E 5 68  ? 287.679 348.325 453.416 1.00 80.16  ? 68  TYR C CD2 1 
ATOM 5797 C CE1 . TYR E 5 68  ? 286.804 346.023 452.224 1.00 80.16  ? 68  TYR C CE1 1 
ATOM 5798 C CE2 . TYR E 5 68  ? 286.337 348.084 453.296 1.00 80.16  ? 68  TYR C CE2 1 
ATOM 5799 C CZ  . TYR E 5 68  ? 285.911 346.931 452.698 1.00 80.16  ? 68  TYR C CZ  1 
ATOM 5800 O OH  . TYR E 5 68  ? 284.575 346.678 452.571 1.00 80.16  ? 68  TYR C OH  1 
ATOM 5801 N N   . GLN E 5 69  ? 292.777 347.820 455.220 1.00 83.54  ? 69  GLN C N   1 
ATOM 5802 C CA  . GLN E 5 69  ? 294.188 348.180 455.208 1.00 83.54  ? 69  GLN C CA  1 
ATOM 5803 C C   . GLN E 5 69  ? 294.982 347.312 456.171 1.00 83.54  ? 69  GLN C C   1 
ATOM 5804 O O   . GLN E 5 69  ? 294.548 347.066 457.298 1.00 83.54  ? 69  GLN C O   1 
ATOM 5805 C CB  . GLN E 5 69  ? 294.367 349.644 455.587 1.00 83.54  ? 69  GLN C CB  1 
ATOM 5806 C CG  . GLN E 5 69  ? 293.322 350.557 455.027 1.00 83.54  ? 69  GLN C CG  1 
ATOM 5807 C CD  . GLN E 5 69  ? 293.119 351.773 455.891 1.00 83.54  ? 69  GLN C CD  1 
ATOM 5808 O OE1 . GLN E 5 69  ? 293.875 352.013 456.828 1.00 83.54  ? 69  GLN C OE1 1 
ATOM 5809 N NE2 . GLN E 5 69  ? 292.091 352.551 455.584 1.00 83.54  ? 69  GLN C NE2 1 
ATOM 5810 N N   . ILE E 5 70  ? 296.157 346.876 455.733 1.00 83.40  ? 70  ILE C N   1 
ATOM 5811 C CA  . ILE E 5 70  ? 297.084 346.132 456.580 1.00 83.40  ? 70  ILE C CA  1 
ATOM 5812 C C   . ILE E 5 70  ? 298.123 347.115 457.106 1.00 83.40  ? 70  ILE C C   1 
ATOM 5813 O O   . ILE E 5 70  ? 298.827 347.734 456.300 1.00 83.40  ? 70  ILE C O   1 
ATOM 5814 C CB  . ILE E 5 70  ? 297.766 345.006 455.806 1.00 83.40  ? 70  ILE C CB  1 
ATOM 5815 C CG1 . ILE E 5 70  ? 296.759 344.296 454.928 1.00 83.40  ? 70  ILE C CG1 1 
ATOM 5816 C CG2 . ILE E 5 70  ? 298.404 344.047 456.757 1.00 83.40  ? 70  ILE C CG2 1 
ATOM 5817 C CD1 . ILE E 5 70  ? 297.362 343.236 454.072 1.00 83.40  ? 70  ILE C CD1 1 
ATOM 5818 N N   . PRO E 5 71  ? 298.256 347.282 458.417 1.00 88.15  ? 71  PRO C N   1 
ATOM 5819 C CA  . PRO E 5 71  ? 299.249 348.226 458.945 1.00 88.15  ? 71  PRO C CA  1 
ATOM 5820 C C   . PRO E 5 71  ? 300.653 347.663 458.803 1.00 88.15  ? 71  PRO C C   1 
ATOM 5821 O O   . PRO E 5 71  ? 300.923 346.532 459.202 1.00 88.15  ? 71  PRO C O   1 
ATOM 5822 C CB  . PRO E 5 71  ? 298.845 348.379 460.414 1.00 88.15  ? 71  PRO C CB  1 
ATOM 5823 C CG  . PRO E 5 71  ? 297.466 347.829 460.500 1.00 88.15  ? 71  PRO C CG  1 
ATOM 5824 C CD  . PRO E 5 71  ? 297.396 346.755 459.480 1.00 88.15  ? 71  PRO C CD  1 
ATOM 5825 N N   . VAL E 5 72  ? 301.543 348.458 458.223 1.00 93.91  ? 72  VAL C N   1 
ATOM 5826 C CA  . VAL E 5 72  ? 302.943 348.103 458.052 1.00 93.91  ? 72  VAL C CA  1 
ATOM 5827 C C   . VAL E 5 72  ? 303.771 349.245 458.616 1.00 93.91  ? 72  VAL C C   1 
ATOM 5828 O O   . VAL E 5 72  ? 303.608 350.397 458.199 1.00 93.91  ? 72  VAL C O   1 
ATOM 5829 C CB  . VAL E 5 72  ? 303.287 347.850 456.577 1.00 93.91  ? 72  VAL C CB  1 
ATOM 5830 C CG1 . VAL E 5 72  ? 304.776 347.882 456.357 1.00 93.91  ? 72  VAL C CG1 1 
ATOM 5831 C CG2 . VAL E 5 72  ? 302.726 346.530 456.134 1.00 93.91  ? 72  VAL C CG2 1 
ATOM 5832 N N   . GLN E 5 73  ? 304.642 348.939 459.570 1.00 105.04 ? 73  GLN C N   1 
ATOM 5833 C CA  . GLN E 5 73  ? 305.505 349.946 460.160 1.00 105.04 ? 73  GLN C CA  1 
ATOM 5834 C C   . GLN E 5 73  ? 306.909 349.390 460.311 1.00 105.04 ? 73  GLN C C   1 
ATOM 5835 O O   . GLN E 5 73  ? 307.131 348.180 460.250 1.00 105.04 ? 73  GLN C O   1 
ATOM 5836 C CB  . GLN E 5 73  ? 304.985 350.414 461.517 1.00 105.04 ? 73  GLN C CB  1 
ATOM 5837 C CG  . GLN E 5 73  ? 305.246 349.439 462.634 1.00 105.04 ? 73  GLN C CG  1 
ATOM 5838 C CD  . GLN E 5 73  ? 304.185 348.377 462.712 1.00 105.04 ? 73  GLN C CD  1 
ATOM 5839 O OE1 . GLN E 5 73  ? 303.027 348.625 462.392 1.00 105.04 ? 73  GLN C OE1 1 
ATOM 5840 N NE2 . GLN E 5 73  ? 304.573 347.180 463.127 1.00 105.04 ? 73  GLN C NE2 1 
ATOM 5841 N N   . SER E 5 74  ? 307.861 350.293 460.508 1.00 112.18 ? 74  SER C N   1 
ATOM 5842 C CA  . SER E 5 74  ? 309.261 349.918 460.678 1.00 112.18 ? 74  SER C CA  1 
ATOM 5843 C C   . SER E 5 74  ? 309.484 349.580 462.143 1.00 112.18 ? 74  SER C C   1 
ATOM 5844 O O   . SER E 5 74  ? 309.662 350.469 462.977 1.00 112.18 ? 74  SER C O   1 
ATOM 5845 C CB  . SER E 5 74  ? 310.183 351.041 460.223 1.00 112.18 ? 74  SER C CB  1 
ATOM 5846 O OG  . SER E 5 74  ? 310.444 351.935 461.289 1.00 112.18 ? 74  SER C OG  1 
ATOM 5847 N N   . ASN E 5 75  ? 309.476 348.292 462.459 1.00 117.41 ? 75  ASN C N   1 
ATOM 5848 C CA  . ASN E 5 75  ? 309.697 347.832 463.818 1.00 117.41 ? 75  ASN C CA  1 
ATOM 5849 C C   . ASN E 5 75  ? 311.191 347.618 464.049 1.00 117.41 ? 75  ASN C C   1 
ATOM 5850 O O   . ASN E 5 75  ? 312.035 348.063 463.267 1.00 117.41 ? 75  ASN C O   1 
ATOM 5851 C CB  . ASN E 5 75  ? 308.904 346.558 464.077 1.00 117.41 ? 75  ASN C CB  1 
ATOM 5852 C CG  . ASN E 5 75  ? 309.368 345.415 463.220 1.00 117.41 ? 75  ASN C CG  1 
ATOM 5853 O OD1 . ASN E 5 75  ? 309.715 345.603 462.058 1.00 117.41 ? 75  ASN C OD1 1 
ATOM 5854 N ND2 . ASN E 5 75  ? 309.395 344.220 463.791 1.00 117.41 ? 75  ASN C ND2 1 
ATOM 5855 N N   . SER E 5 76  ? 311.534 346.934 465.137 1.00 126.02 ? 76  SER C N   1 
ATOM 5856 C CA  . SER E 5 76  ? 312.921 346.641 465.464 1.00 126.02 ? 76  SER C CA  1 
ATOM 5857 C C   . SER E 5 76  ? 313.276 345.168 465.314 1.00 126.02 ? 76  SER C C   1 
ATOM 5858 O O   . SER E 5 76  ? 314.464 344.830 465.328 1.00 126.02 ? 76  SER C O   1 
ATOM 5859 C CB  . SER E 5 76  ? 313.233 347.089 466.896 1.00 126.02 ? 76  SER C CB  1 
ATOM 5860 O OG  . SER E 5 76  ? 312.601 346.242 467.838 1.00 126.02 ? 76  SER C OG  1 
ATOM 5861 N N   . ASP E 5 77  ? 312.287 344.291 465.175 1.00 127.97 ? 77  ASP C N   1 
ATOM 5862 C CA  . ASP E 5 77  ? 312.533 342.863 465.044 1.00 127.97 ? 77  ASP C CA  1 
ATOM 5863 C C   . ASP E 5 77  ? 312.707 342.487 463.580 1.00 127.97 ? 77  ASP C C   1 
ATOM 5864 O O   . ASP E 5 77  ? 312.003 342.999 462.704 1.00 127.97 ? 77  ASP C O   1 
ATOM 5865 C CB  . ASP E 5 77  ? 311.383 342.060 465.651 1.00 127.97 ? 77  ASP C CB  1 
ATOM 5866 C CG  . ASP E 5 77  ? 310.946 342.599 466.994 1.00 127.97 ? 77  ASP C CG  1 
ATOM 5867 O OD1 . ASP E 5 77  ? 311.801 343.137 467.725 1.00 127.97 ? 77  ASP C OD1 1 
ATOM 5868 O OD2 . ASP E 5 77  ? 309.744 342.487 467.316 1.00 127.97 ? 77  ASP C OD2 1 
ATOM 5869 N N   . ASN E 5 78  ? 313.649 341.589 463.321 1.00 124.89 ? 78  ASN C N   1 
ATOM 5870 C CA  . ASN E 5 78  ? 313.894 341.092 461.971 1.00 124.89 ? 78  ASN C CA  1 
ATOM 5871 C C   . ASN E 5 78  ? 313.167 339.762 461.836 1.00 124.89 ? 78  ASN C C   1 
ATOM 5872 O O   . ASN E 5 78  ? 313.522 338.776 462.485 1.00 124.89 ? 78  ASN C O   1 
ATOM 5873 C CB  . ASN E 5 78  ? 315.389 340.954 461.711 1.00 124.89 ? 78  ASN C CB  1 
ATOM 5874 C CG  . ASN E 5 78  ? 315.722 340.881 460.234 1.00 124.89 ? 78  ASN C CG  1 
ATOM 5875 O OD1 . ASN E 5 78  ? 315.072 340.172 459.466 1.00 124.89 ? 78  ASN C OD1 1 
ATOM 5876 N ND2 . ASN E 5 78  ? 316.741 341.626 459.826 1.00 124.89 ? 78  ASN C ND2 1 
ATOM 5877 N N   . GLY E 5 79  ? 312.139 339.737 460.998 1.00 113.25 ? 79  GLY C N   1 
ATOM 5878 C CA  . GLY E 5 79  ? 311.365 338.533 460.797 1.00 113.25 ? 79  GLY C CA  1 
ATOM 5879 C C   . GLY E 5 79  ? 310.131 338.529 461.666 1.00 113.25 ? 79  GLY C C   1 
ATOM 5880 O O   . GLY E 5 79  ? 310.202 338.235 462.861 1.00 113.25 ? 79  GLY C O   1 
ATOM 5881 N N   . LYS E 5 80  ? 308.990 338.847 461.071 1.00 100.67 ? 80  LYS C N   1 
ATOM 5882 C CA  . LYS E 5 80  ? 307.747 338.948 461.812 1.00 100.67 ? 80  LYS C CA  1 
ATOM 5883 C C   . LYS E 5 80  ? 306.608 338.765 460.831 1.00 100.67 ? 80  LYS C C   1 
ATOM 5884 O O   . LYS E 5 80  ? 306.776 338.962 459.628 1.00 100.67 ? 80  LYS C O   1 
ATOM 5885 C CB  . LYS E 5 80  ? 307.623 340.291 462.527 1.00 100.67 ? 80  LYS C CB  1 
ATOM 5886 C CG  . LYS E 5 80  ? 306.997 340.191 463.895 1.00 100.67 ? 80  LYS C CG  1 
ATOM 5887 C CD  . LYS E 5 80  ? 307.402 341.362 464.766 1.00 100.67 ? 80  LYS C CD  1 
ATOM 5888 C CE  . LYS E 5 80  ? 306.501 342.558 464.527 1.00 100.67 ? 80  LYS C CE  1 
ATOM 5889 N NZ  . LYS E 5 80  ? 306.800 343.667 465.469 1.00 100.67 ? 80  LYS C NZ  1 
ATOM 5890 N N   . GLN E 5 81  ? 305.455 338.381 461.352 1.00 94.87  ? 81  GLN C N   1 
ATOM 5891 C CA  . GLN E 5 81  ? 304.322 338.105 460.486 1.00 94.87  ? 81  GLN C CA  1 
ATOM 5892 C C   . GLN E 5 81  ? 303.541 339.382 460.230 1.00 94.87  ? 81  GLN C C   1 
ATOM 5893 O O   . GLN E 5 81  ? 303.120 340.059 461.169 1.00 94.87  ? 81  GLN C O   1 
ATOM 5894 C CB  . GLN E 5 81  ? 303.431 337.051 461.127 1.00 94.87  ? 81  GLN C CB  1 
ATOM 5895 C CG  . GLN E 5 81  ? 302.461 336.412 460.181 1.00 94.87  ? 81  GLN C CG  1 
ATOM 5896 C CD  . GLN E 5 81  ? 302.170 334.990 460.567 1.00 94.87  ? 81  GLN C CD  1 
ATOM 5897 O OE1 . GLN E 5 81  ? 302.877 334.409 461.383 1.00 94.87  ? 81  GLN C OE1 1 
ATOM 5898 N NE2 . GLN E 5 81  ? 301.133 334.415 459.982 1.00 94.87  ? 81  GLN C NE2 1 
ATOM 5899 N N   . VAL E 5 82  ? 303.356 339.724 458.959 1.00 87.63  ? 82  VAL C N   1 
ATOM 5900 C CA  . VAL E 5 82  ? 302.562 340.901 458.624 1.00 87.63  ? 82  VAL C CA  1 
ATOM 5901 C C   . VAL E 5 82  ? 301.077 340.579 458.706 1.00 87.63  ? 82  VAL C C   1 
ATOM 5902 O O   . VAL E 5 82  ? 300.317 341.259 459.401 1.00 87.63  ? 82  VAL C O   1 
ATOM 5903 C CB  . VAL E 5 82  ? 302.955 341.444 457.240 1.00 87.63  ? 82  VAL C CB  1 
ATOM 5904 C CG1 . VAL E 5 82  ? 301.941 342.439 456.759 1.00 87.63  ? 82  VAL C CG1 1 
ATOM 5905 C CG2 . VAL E 5 82  ? 304.292 342.113 457.326 1.00 87.63  ? 82  VAL C CG2 1 
ATOM 5906 N N   . PHE E 5 83  ? 300.645 339.531 458.008 1.00 85.93  ? 83  PHE C N   1 
ATOM 5907 C CA  . PHE E 5 83  ? 299.289 339.023 458.146 1.00 85.93  ? 83  PHE C CA  1 
ATOM 5908 C C   . PHE E 5 83  ? 299.292 337.536 457.843 1.00 85.93  ? 83  PHE C C   1 
ATOM 5909 O O   . PHE E 5 83  ? 300.338 336.925 457.634 1.00 85.93  ? 83  PHE C O   1 
ATOM 5910 C CB  . PHE E 5 83  ? 298.300 339.765 457.246 1.00 85.93  ? 83  PHE C CB  1 
ATOM 5911 C CG  . PHE E 5 83  ? 298.531 339.579 455.776 1.00 85.93  ? 83  PHE C CG  1 
ATOM 5912 C CD1 . PHE E 5 83  ? 299.418 340.387 455.102 1.00 85.93  ? 83  PHE C CD1 1 
ATOM 5913 C CD2 . PHE E 5 83  ? 297.817 338.640 455.057 1.00 85.93  ? 83  PHE C CD2 1 
ATOM 5914 C CE1 . PHE E 5 83  ? 299.614 340.242 453.754 1.00 85.93  ? 83  PHE C CE1 1 
ATOM 5915 C CE2 . PHE E 5 83  ? 298.021 338.486 453.714 1.00 85.93  ? 83  PHE C CE2 1 
ATOM 5916 C CZ  . PHE E 5 83  ? 298.922 339.286 453.064 1.00 85.93  ? 83  PHE C CZ  1 
ATOM 5917 N N   . GLY E 5 84  ? 298.100 336.959 457.827 1.00 87.97  ? 84  GLY C N   1 
ATOM 5918 C CA  . GLY E 5 84  ? 297.931 335.578 457.439 1.00 87.97  ? 84  GLY C CA  1 
ATOM 5919 C C   . GLY E 5 84  ? 296.487 335.161 457.563 1.00 87.97  ? 84  GLY C C   1 
ATOM 5920 O O   . GLY E 5 84  ? 295.851 335.425 458.584 1.00 87.97  ? 84  GLY C O   1 
ATOM 5921 N N   . PHE E 5 85  ? 295.950 334.511 456.536 1.00 87.46  ? 85  PHE C N   1 
ATOM 5922 C CA  . PHE E 5 85  ? 294.564 334.124 456.586 1.00 87.46  ? 85  PHE C CA  1 
ATOM 5923 C C   . PHE E 5 85  ? 294.400 332.811 455.846 1.00 87.46  ? 85  PHE C C   1 
ATOM 5924 O O   . PHE E 5 85  ? 295.036 332.619 454.804 1.00 87.46  ? 85  PHE C O   1 
ATOM 5925 C CB  . PHE E 5 85  ? 293.634 335.191 455.992 1.00 87.46  ? 85  PHE C CB  1 
ATOM 5926 C CG  . PHE E 5 85  ? 293.869 335.497 454.537 1.00 87.46  ? 85  PHE C CG  1 
ATOM 5927 C CD1 . PHE E 5 85  ? 294.825 336.415 454.157 1.00 87.46  ? 85  PHE C CD1 1 
ATOM 5928 C CD2 . PHE E 5 85  ? 293.095 334.909 453.557 1.00 87.46  ? 85  PHE C CD2 1 
ATOM 5929 C CE1 . PHE E 5 85  ? 295.024 336.715 452.836 1.00 87.46  ? 85  PHE C CE1 1 
ATOM 5930 C CE2 . PHE E 5 85  ? 293.296 335.203 452.233 1.00 87.46  ? 85  PHE C CE2 1 
ATOM 5931 C CZ  . PHE E 5 85  ? 294.260 336.108 451.874 1.00 87.46  ? 85  PHE C CZ  1 
ATOM 5932 N N   . PRO E 5 86  ? 293.580 331.898 456.347 1.00 93.09  ? 86  PRO C N   1 
ATOM 5933 C CA  . PRO E 5 86  ? 293.389 330.622 455.662 1.00 93.09  ? 86  PRO C CA  1 
ATOM 5934 C C   . PRO E 5 86  ? 292.480 330.790 454.458 1.00 93.09  ? 86  PRO C C   1 
ATOM 5935 O O   . PRO E 5 86  ? 291.796 331.795 454.294 1.00 93.09  ? 86  PRO C O   1 
ATOM 5936 C CB  . PRO E 5 86  ? 292.730 329.756 456.727 1.00 93.09  ? 86  PRO C CB  1 
ATOM 5937 C CG  . PRO E 5 86  ? 291.957 330.723 457.522 1.00 93.09  ? 86  PRO C CG  1 
ATOM 5938 C CD  . PRO E 5 86  ? 292.777 331.975 457.575 1.00 93.09  ? 86  PRO C CD  1 
ATOM 5939 N N   . LEU E 5 87  ? 292.486 329.770 453.608 1.00 97.26  ? 87  LEU C N   1 
ATOM 5940 C CA  . LEU E 5 87  ? 291.606 329.726 452.452 1.00 97.26  ? 87  LEU C CA  1 
ATOM 5941 C C   . LEU E 5 87  ? 290.462 328.738 452.648 1.00 97.26  ? 87  LEU C C   1 
ATOM 5942 O O   . LEU E 5 87  ? 289.867 328.286 451.665 1.00 97.26  ? 87  LEU C O   1 
ATOM 5943 C CB  . LEU E 5 87  ? 292.404 329.388 451.196 1.00 97.26  ? 87  LEU C CB  1 
ATOM 5944 C CG  . LEU E 5 87  ? 293.423 330.423 450.731 1.00 97.26  ? 87  LEU C CG  1 
ATOM 5945 C CD1 . LEU E 5 87  ? 293.920 330.091 449.350 1.00 97.26  ? 87  LEU C CD1 1 
ATOM 5946 C CD2 . LEU E 5 87  ? 292.822 331.798 450.739 1.00 97.26  ? 87  LEU C CD2 1 
ATOM 5947 N N   . GLN E 5 88  ? 290.156 328.386 453.906 1.00 110.66 ? 88  GLN C N   1 
ATOM 5948 C CA  . GLN E 5 88  ? 289.048 327.514 454.287 1.00 110.66 ? 88  GLN C CA  1 
ATOM 5949 C C   . GLN E 5 88  ? 287.739 328.132 453.814 1.00 110.66 ? 88  GLN C C   1 
ATOM 5950 O O   . GLN E 5 88  ? 287.413 329.260 454.201 1.00 110.66 ? 88  GLN C O   1 
ATOM 5951 C CB  . GLN E 5 88  ? 289.021 327.300 455.802 1.00 110.66 ? 88  GLN C CB  1 
ATOM 5952 C CG  . GLN E 5 88  ? 287.966 326.320 456.303 1.00 110.66 ? 88  GLN C CG  1 
ATOM 5953 C CD  . GLN E 5 88  ? 288.474 324.892 456.390 1.00 110.66 ? 88  GLN C CD  1 
ATOM 5954 O OE1 . GLN E 5 88  ? 289.615 324.647 456.772 1.00 110.66 ? 88  GLN C OE1 1 
ATOM 5955 N NE2 . GLN E 5 88  ? 287.616 323.939 456.052 1.00 110.66 ? 88  GLN C NE2 1 
ATOM 5956 N N   . PRO E 5 89  ? 286.978 327.435 452.973 1.00 107.58 ? 89  PRO C N   1 
ATOM 5957 C CA  . PRO E 5 89  ? 285.877 328.082 452.246 1.00 107.58 ? 89  PRO C CA  1 
ATOM 5958 C C   . PRO E 5 89  ? 284.673 328.371 453.134 1.00 107.58 ? 89  PRO C C   1 
ATOM 5959 O O   . PRO E 5 89  ? 284.075 327.461 453.711 1.00 107.58 ? 89  PRO C O   1 
ATOM 5960 C CB  . PRO E 5 89  ? 285.527 327.059 451.160 1.00 107.58 ? 89  PRO C CB  1 
ATOM 5961 C CG  . PRO E 5 89  ? 286.681 326.112 451.131 1.00 107.58 ? 89  PRO C CG  1 
ATOM 5962 C CD  . PRO E 5 89  ? 287.193 326.058 452.514 1.00 107.58 ? 89  PRO C CD  1 
ATOM 5963 N N   . GLY E 5 90  ? 284.329 329.658 453.245 1.00 106.34 ? 90  GLY C N   1 
ATOM 5964 C CA  . GLY E 5 90  ? 283.098 330.091 453.870 1.00 106.34 ? 90  GLY C CA  1 
ATOM 5965 C C   . GLY E 5 90  ? 283.064 330.053 455.382 1.00 106.34 ? 90  GLY C C   1 
ATOM 5966 O O   . GLY E 5 90  ? 282.119 330.581 455.976 1.00 106.34 ? 90  GLY C O   1 
ATOM 5967 N N   . ALA E 5 91  ? 284.059 329.452 456.032 1.00 114.15 ? 91  ALA C N   1 
ATOM 5968 C CA  . ALA E 5 91  ? 284.051 329.295 457.486 1.00 114.15 ? 91  ALA C CA  1 
ATOM 5969 C C   . ALA E 5 91  ? 284.546 330.590 458.125 1.00 114.15 ? 91  ALA C C   1 
ATOM 5970 O O   . ALA E 5 91  ? 285.699 330.710 458.547 1.00 114.15 ? 91  ALA C O   1 
ATOM 5971 C CB  . ALA E 5 91  ? 284.899 328.100 457.899 1.00 114.15 ? 91  ALA C CB  1 
ATOM 5972 N N   . ASN E 5 92  ? 283.646 331.584 458.150 1.00 110.22 ? 92  ASN C N   1 
ATOM 5973 C CA  . ASN E 5 92  ? 283.787 332.938 458.705 1.00 110.22 ? 92  ASN C CA  1 
ATOM 5974 C C   . ASN E 5 92  ? 285.054 333.686 458.291 1.00 110.22 ? 92  ASN C C   1 
ATOM 5975 O O   . ASN E 5 92  ? 285.439 334.664 458.940 1.00 110.22 ? 92  ASN C O   1 
ATOM 5976 C CB  . ASN E 5 92  ? 283.647 332.905 460.241 1.00 110.22 ? 92  ASN C CB  1 
ATOM 5977 C CG  . ASN E 5 92  ? 284.859 332.322 460.963 1.00 110.22 ? 92  ASN C CG  1 
ATOM 5978 O OD1 . ASN E 5 92  ? 285.861 332.999 461.194 1.00 110.22 ? 92  ASN C OD1 1 
ATOM 5979 N ND2 . ASN E 5 92  ? 284.763 331.050 461.325 1.00 110.22 ? 92  ASN C ND2 1 
ATOM 5980 N N   . ASN E 5 93  ? 285.662 333.300 457.174 1.00 99.63  ? 93  ASN C N   1 
ATOM 5981 C CA  . ASN E 5 93  ? 286.926 333.888 456.774 1.00 99.63  ? 93  ASN C CA  1 
ATOM 5982 C C   . ASN E 5 93  ? 286.702 335.224 456.072 1.00 99.63  ? 93  ASN C C   1 
ATOM 5983 O O   . ASN E 5 93  ? 285.600 335.776 456.047 1.00 99.63  ? 93  ASN C O   1 
ATOM 5984 C CB  . ASN E 5 93  ? 287.714 332.915 455.904 1.00 99.63  ? 93  ASN C CB  1 
ATOM 5985 C CG  . ASN E 5 93  ? 286.913 332.387 454.753 1.00 99.63  ? 93  ASN C CG  1 
ATOM 5986 O OD1 . ASN E 5 93  ? 285.734 332.688 454.614 1.00 99.63  ? 93  ASN C OD1 1 
ATOM 5987 N ND2 . ASN E 5 93  ? 287.557 331.618 453.896 1.00 99.63  ? 93  ASN C ND2 1 
ATOM 5988 N N   . VAL E 5 94  ? 287.778 335.749 455.492 1.00 90.24  ? 94  VAL C N   1 
ATOM 5989 C CA  . VAL E 5 94  ? 287.762 337.105 454.970 1.00 90.24  ? 94  VAL C CA  1 
ATOM 5990 C C   . VAL E 5 94  ? 287.300 337.194 453.523 1.00 90.24  ? 94  VAL C C   1 
ATOM 5991 O O   . VAL E 5 94  ? 286.903 338.277 453.080 1.00 90.24  ? 94  VAL C O   1 
ATOM 5992 C CB  . VAL E 5 94  ? 289.156 337.719 455.129 1.00 90.24  ? 94  VAL C CB  1 
ATOM 5993 C CG1 . VAL E 5 94  ? 289.528 337.729 456.579 1.00 90.24  ? 94  VAL C CG1 1 
ATOM 5994 C CG2 . VAL E 5 94  ? 290.157 336.915 454.367 1.00 90.24  ? 94  VAL C CG2 1 
ATOM 5995 N N   . LEU E 5 95  ? 287.316 336.092 452.779 1.00 88.03  ? 95  LEU C N   1 
ATOM 5996 C CA  . LEU E 5 95  ? 286.818 336.074 451.413 1.00 88.03  ? 95  LEU C CA  1 
ATOM 5997 C C   . LEU E 5 95  ? 285.335 335.768 451.343 1.00 88.03  ? 95  LEU C C   1 
ATOM 5998 O O   . LEU E 5 95  ? 284.849 335.332 450.298 1.00 88.03  ? 95  LEU C O   1 
ATOM 5999 C CB  . LEU E 5 95  ? 287.591 335.051 450.586 1.00 88.03  ? 95  LEU C CB  1 
ATOM 6000 C CG  . LEU E 5 95  ? 289.102 335.136 450.722 1.00 88.03  ? 95  LEU C CG  1 
ATOM 6001 C CD1 . LEU E 5 95  ? 289.752 333.932 450.110 1.00 88.03  ? 95  LEU C CD1 1 
ATOM 6002 C CD2 . LEU E 5 95  ? 289.583 336.379 450.044 1.00 88.03  ? 95  LEU C CD2 1 
ATOM 6003 N N   . ASN E 5 96  ? 284.608 335.971 452.434 1.00 91.24  ? 96  ASN C N   1 
ATOM 6004 C CA  . ASN E 5 96  ? 283.223 335.533 452.495 1.00 91.24  ? 96  ASN C CA  1 
ATOM 6005 C C   . ASN E 5 96  ? 282.297 336.527 451.813 1.00 91.24  ? 96  ASN C C   1 
ATOM 6006 O O   . ASN E 5 96  ? 281.552 336.167 450.899 1.00 91.24  ? 96  ASN C O   1 
ATOM 6007 C CB  . ASN E 5 96  ? 282.814 335.329 453.948 1.00 91.24  ? 96  ASN C CB  1 
ATOM 6008 C CG  . ASN E 5 96  ? 281.727 334.314 454.095 1.00 91.24  ? 96  ASN C CG  1 
ATOM 6009 O OD1 . ASN E 5 96  ? 281.441 333.566 453.165 1.00 91.24  ? 96  ASN C OD1 1 
ATOM 6010 N ND2 . ASN E 5 96  ? 281.112 334.270 455.267 1.00 91.24  ? 96  ASN C ND2 1 
ATOM 6011 N N   . ARG E 5 97  ? 282.335 337.785 452.239 1.00 90.06  ? 97  ARG C N   1 
ATOM 6012 C CA  . ARG E 5 97  ? 281.409 338.793 451.748 1.00 90.06  ? 97  ARG C CA  1 
ATOM 6013 C C   . ARG E 5 97  ? 281.930 339.536 450.534 1.00 90.06  ? 97  ARG C C   1 
ATOM 6014 O O   . ARG E 5 97  ? 281.268 340.465 450.070 1.00 90.06  ? 97  ARG C O   1 
ATOM 6015 C CB  . ARG E 5 97  ? 281.083 339.813 452.839 1.00 90.06  ? 97  ARG C CB  1 
ATOM 6016 C CG  . ARG E 5 97  ? 280.780 339.239 454.201 1.00 90.06  ? 97  ARG C CG  1 
ATOM 6017 C CD  . ARG E 5 97  ? 279.669 338.215 454.178 1.00 90.06  ? 97  ARG C CD  1 
ATOM 6018 N NE  . ARG E 5 97  ? 278.387 338.760 453.756 1.00 90.06  ? 97  ARG C NE  1 
ATOM 6019 C CZ  . ARG E 5 97  ? 277.476 339.229 454.596 1.00 90.06  ? 97  ARG C CZ  1 
ATOM 6020 N NH1 . ARG E 5 97  ? 277.715 339.232 455.900 1.00 90.06  ? 97  ARG C NH1 1 
ATOM 6021 N NH2 . ARG E 5 97  ? 276.327 339.694 454.135 1.00 90.06  ? 97  ARG C NH2 1 
ATOM 6022 N N   . THR E 5 98  ? 283.090 339.160 450.004 1.00 86.35  ? 98  THR C N   1 
ATOM 6023 C CA  . THR E 5 98  ? 283.608 339.833 448.825 1.00 86.35  ? 98  THR C CA  1 
ATOM 6024 C C   . THR E 5 98  ? 282.804 339.435 447.594 1.00 86.35  ? 98  THR C C   1 
ATOM 6025 O O   . THR E 5 98  ? 281.935 338.565 447.639 1.00 86.35  ? 98  THR C O   1 
ATOM 6026 C CB  . THR E 5 98  ? 285.078 339.510 448.619 1.00 86.35  ? 98  THR C CB  1 
ATOM 6027 O OG1 . THR E 5 98  ? 285.527 340.157 447.428 1.00 86.35  ? 98  THR C OG1 1 
ATOM 6028 C CG2 . THR E 5 98  ? 285.262 338.041 448.446 1.00 86.35  ? 98  THR C CG2 1 
ATOM 6029 N N   . LEU E 5 99  ? 283.105 340.076 446.468 1.00 84.07  ? 99  LEU C N   1 
ATOM 6030 C CA  . LEU E 5 99  ? 282.297 339.878 445.273 1.00 84.07  ? 99  LEU C CA  1 
ATOM 6031 C C   . LEU E 5 99  ? 282.542 338.520 444.636 1.00 84.07  ? 99  LEU C C   1 
ATOM 6032 O O   . LEU E 5 99  ? 281.656 337.998 443.959 1.00 84.07  ? 99  LEU C O   1 
ATOM 6033 C CB  . LEU E 5 99  ? 282.565 341.008 444.289 1.00 84.07  ? 99  LEU C CB  1 
ATOM 6034 C CG  . LEU E 5 99  ? 281.726 341.118 443.034 1.00 84.07  ? 99  LEU C CG  1 
ATOM 6035 C CD1 . LEU E 5 99  ? 280.292 341.173 443.439 1.00 84.07  ? 99  LEU C CD1 1 
ATOM 6036 C CD2 . LEU E 5 99  ? 282.101 342.381 442.331 1.00 84.07  ? 99  LEU C CD2 1 
ATOM 6037 N N   . LEU E 5 100 ? 283.703 337.921 444.871 1.00 85.77  ? 100 LEU C N   1 
ATOM 6038 C CA  . LEU E 5 100 ? 283.889 336.526 444.499 1.00 85.77  ? 100 LEU C CA  1 
ATOM 6039 C C   . LEU E 5 100 ? 283.105 335.613 445.421 1.00 85.77  ? 100 LEU C C   1 
ATOM 6040 O O   . LEU E 5 100 ? 282.386 334.723 444.965 1.00 85.77  ? 100 LEU C O   1 
ATOM 6041 C CB  . LEU E 5 100 ? 285.364 336.159 444.544 1.00 85.77  ? 100 LEU C CB  1 
ATOM 6042 C CG  . LEU E 5 100 ? 285.625 334.687 444.274 1.00 85.77  ? 100 LEU C CG  1 
ATOM 6043 C CD1 . LEU E 5 100 ? 285.225 334.358 442.860 1.00 85.77  ? 100 LEU C CD1 1 
ATOM 6044 C CD2 . LEU E 5 100 ? 287.072 334.358 444.520 1.00 85.77  ? 100 LEU C CD2 1 
ATOM 6045 N N   . GLY E 5 101 ? 283.219 335.833 446.723 1.00 87.15  ? 101 GLY C N   1 
ATOM 6046 C CA  . GLY E 5 101 ? 282.559 334.971 447.679 1.00 87.15  ? 101 GLY C CA  1 
ATOM 6047 C C   . GLY E 5 101 ? 281.069 335.144 447.777 1.00 87.15  ? 101 GLY C C   1 
ATOM 6048 O O   . GLY E 5 101 ? 280.412 334.303 448.388 1.00 87.15  ? 101 GLY C O   1 
ATOM 6049 N N   . GLU E 5 102 ? 280.507 336.188 447.183 1.00 93.20  ? 102 GLU C N   1 
ATOM 6050 C CA  . GLU E 5 102 ? 279.067 336.373 447.252 1.00 93.20  ? 102 GLU C CA  1 
ATOM 6051 C C   . GLU E 5 102 ? 278.330 335.635 446.155 1.00 93.20  ? 102 GLU C C   1 
ATOM 6052 O O   . GLU E 5 102 ? 277.132 335.385 446.293 1.00 93.20  ? 102 GLU C O   1 
ATOM 6053 C CB  . GLU E 5 102 ? 278.706 337.858 447.182 1.00 93.20  ? 102 GLU C CB  1 
ATOM 6054 C CG  . GLU E 5 102 ? 278.638 338.578 448.530 1.00 93.20  ? 102 GLU C CG  1 
ATOM 6055 C CD  . GLU E 5 102 ? 277.500 338.135 449.459 1.00 93.20  ? 102 GLU C CD  1 
ATOM 6056 O OE1 . GLU E 5 102 ? 276.623 337.330 449.071 1.00 93.20  ? 102 GLU C OE1 1 
ATOM 6057 O OE2 . GLU E 5 102 ? 277.481 338.621 450.612 1.00 93.20  ? 102 GLU C OE2 1 
ATOM 6058 N N   . ILE E 5 103 ? 279.005 335.304 445.063 1.00 87.32  ? 103 ILE C N   1 
ATOM 6059 C CA  . ILE E 5 103 ? 278.412 334.443 444.053 1.00 87.32  ? 103 ILE C CA  1 
ATOM 6060 C C   . ILE E 5 103 ? 278.592 332.980 444.414 1.00 87.32  ? 103 ILE C C   1 
ATOM 6061 O O   . ILE E 5 103 ? 277.693 332.167 444.203 1.00 87.32  ? 103 ILE C O   1 
ATOM 6062 C CB  . ILE E 5 103 ? 279.014 334.764 442.678 1.00 87.32  ? 103 ILE C CB  1 
ATOM 6063 C CG1 . ILE E 5 103 ? 278.932 336.258 442.420 1.00 87.32  ? 103 ILE C CG1 1 
ATOM 6064 C CG2 . ILE E 5 103 ? 278.290 334.027 441.590 1.00 87.32  ? 103 ILE C CG2 1 
ATOM 6065 C CD1 . ILE E 5 103 ? 279.609 336.670 441.159 1.00 87.32  ? 103 ILE C CD1 1 
ATOM 6066 N N   . LEU E 5 104 ? 279.730 332.621 444.998 1.00 86.32  ? 104 LEU C N   1 
ATOM 6067 C CA  . LEU E 5 104 ? 279.986 331.224 445.300 1.00 86.32  ? 104 LEU C CA  1 
ATOM 6068 C C   . LEU E 5 104 ? 279.273 330.735 446.550 1.00 86.32  ? 104 LEU C C   1 
ATOM 6069 O O   . LEU E 5 104 ? 279.438 329.568 446.906 1.00 86.32  ? 104 LEU C O   1 
ATOM 6070 C CB  . LEU E 5 104 ? 281.483 330.986 445.437 1.00 86.32  ? 104 LEU C CB  1 
ATOM 6071 C CG  . LEU E 5 104 ? 282.313 331.363 444.217 1.00 86.32  ? 104 LEU C CG  1 
ATOM 6072 C CD1 . LEU E 5 104 ? 283.716 330.863 444.384 1.00 86.32  ? 104 LEU C CD1 1 
ATOM 6073 C CD2 . LEU E 5 104 ? 281.711 330.807 442.947 1.00 86.32  ? 104 LEU C CD2 1 
ATOM 6074 N N   . ASN E 5 105 ? 278.506 331.578 447.233 1.00 91.75  ? 105 ASN C N   1 
ATOM 6075 C CA  . ASN E 5 105 ? 277.568 331.081 448.226 1.00 91.75  ? 105 ASN C CA  1 
ATOM 6076 C C   . ASN E 5 105 ? 276.202 330.781 447.648 1.00 91.75  ? 105 ASN C C   1 
ATOM 6077 O O   . ASN E 5 105 ? 275.279 330.499 448.411 1.00 91.75  ? 105 ASN C O   1 
ATOM 6078 C CB  . ASN E 5 105 ? 277.406 332.057 449.387 1.00 91.75  ? 105 ASN C CB  1 
ATOM 6079 C CG  . ASN E 5 105 ? 278.526 331.960 450.378 1.00 91.75  ? 105 ASN C CG  1 
ATOM 6080 O OD1 . ASN E 5 105 ? 279.263 332.908 450.601 1.00 91.75  ? 105 ASN C OD1 1 
ATOM 6081 N ND2 . ASN E 5 105 ? 278.663 330.796 450.986 1.00 91.75  ? 105 ASN C ND2 1 
ATOM 6082 N N   . TYR E 5 106 ? 276.037 330.850 446.335 1.00 91.18  ? 106 TYR C N   1 
ATOM 6083 C CA  . TYR E 5 106 ? 274.807 330.365 445.736 1.00 91.18  ? 106 TYR C CA  1 
ATOM 6084 C C   . TYR E 5 106 ? 274.918 328.929 445.261 1.00 91.18  ? 106 TYR C C   1 
ATOM 6085 O O   . TYR E 5 106 ? 273.891 328.280 445.055 1.00 91.18  ? 106 TYR C O   1 
ATOM 6086 C CB  . TYR E 5 106 ? 274.392 331.253 444.565 1.00 91.18  ? 106 TYR C CB  1 
ATOM 6087 C CG  . TYR E 5 106 ? 273.704 332.517 444.993 1.00 91.18  ? 106 TYR C CG  1 
ATOM 6088 C CD1 . TYR E 5 106 ? 272.413 332.489 445.480 1.00 91.18  ? 106 TYR C CD1 1 
ATOM 6089 C CD2 . TYR E 5 106 ? 274.344 333.738 444.904 1.00 91.18  ? 106 TYR C CD2 1 
ATOM 6090 C CE1 . TYR E 5 106 ? 271.781 333.640 445.877 1.00 91.18  ? 106 TYR C CE1 1 
ATOM 6091 C CE2 . TYR E 5 106 ? 273.720 334.893 445.297 1.00 91.18  ? 106 TYR C CE2 1 
ATOM 6092 C CZ  . TYR E 5 106 ? 272.442 334.836 445.782 1.00 91.18  ? 106 TYR C CZ  1 
ATOM 6093 O OH  . TYR E 5 106 ? 271.817 335.986 446.178 1.00 91.18  ? 106 TYR C OH  1 
ATOM 6094 N N   . TYR E 5 107 ? 276.127 328.411 445.098 1.00 90.90  ? 107 TYR C N   1 
ATOM 6095 C CA  . TYR E 5 107 ? 276.333 327.070 444.587 1.00 90.90  ? 107 TYR C CA  1 
ATOM 6096 C C   . TYR E 5 107 ? 276.982 326.200 445.649 1.00 90.90  ? 107 TYR C C   1 
ATOM 6097 O O   . TYR E 5 107 ? 277.527 326.701 446.632 1.00 90.90  ? 107 TYR C O   1 
ATOM 6098 C CB  . TYR E 5 107 ? 277.190 327.107 443.345 1.00 90.90  ? 107 TYR C CB  1 
ATOM 6099 C CG  . TYR E 5 107 ? 276.595 327.959 442.267 1.00 90.90  ? 107 TYR C CG  1 
ATOM 6100 C CD1 . TYR E 5 107 ? 275.564 327.485 441.486 1.00 90.90  ? 107 TYR C CD1 1 
ATOM 6101 C CD2 . TYR E 5 107 ? 277.059 329.234 442.034 1.00 90.90  ? 107 TYR C CD2 1 
ATOM 6102 C CE1 . TYR E 5 107 ? 275.009 328.255 440.499 1.00 90.90  ? 107 TYR C CE1 1 
ATOM 6103 C CE2 . TYR E 5 107 ? 276.513 330.015 441.049 1.00 90.90  ? 107 TYR C CE2 1 
ATOM 6104 C CZ  . TYR E 5 107 ? 275.488 329.517 440.286 1.00 90.90  ? 107 TYR C CZ  1 
ATOM 6105 O OH  . TYR E 5 107 ? 274.934 330.284 439.297 1.00 90.90  ? 107 TYR C OH  1 
ATOM 6106 N N   . THR E 5 108 ? 276.916 324.885 445.450 1.00 94.22  ? 108 THR C N   1 
ATOM 6107 C CA  . THR E 5 108 ? 277.467 323.959 446.425 1.00 94.22  ? 108 THR C CA  1 
ATOM 6108 C C   . THR E 5 108 ? 278.742 323.270 445.968 1.00 94.22  ? 108 THR C C   1 
ATOM 6109 O O   . THR E 5 108 ? 279.493 322.784 446.816 1.00 94.22  ? 108 THR C O   1 
ATOM 6110 C CB  . THR E 5 108 ? 276.444 322.886 446.786 1.00 94.22  ? 108 THR C CB  1 
ATOM 6111 O OG1 . THR E 5 108 ? 276.295 321.993 445.682 1.00 94.22  ? 108 THR C OG1 1 
ATOM 6112 C CG2 . THR E 5 108 ? 275.117 323.511 447.095 1.00 94.22  ? 108 THR C CG2 1 
ATOM 6113 N N   . HIS E 5 109 ? 279.005 323.203 444.668 1.00 97.11  ? 109 HIS C N   1 
ATOM 6114 C CA  . HIS E 5 109 ? 280.224 322.596 444.147 1.00 97.11  ? 109 HIS C CA  1 
ATOM 6115 C C   . HIS E 5 109 ? 280.901 323.576 443.207 1.00 97.11  ? 109 HIS C C   1 
ATOM 6116 O O   . HIS E 5 109 ? 280.301 323.996 442.215 1.00 97.11  ? 109 HIS C O   1 
ATOM 6117 C CB  . HIS E 5 109 ? 279.916 321.295 443.412 1.00 97.11  ? 109 HIS C CB  1 
ATOM 6118 C CG  . HIS E 5 109 ? 279.337 320.230 444.285 1.00 97.11  ? 109 HIS C CG  1 
ATOM 6119 N ND1 . HIS E 5 109 ? 278.409 319.320 443.829 1.00 97.11  ? 109 HIS C ND1 1 
ATOM 6120 C CD2 . HIS E 5 109 ? 279.562 319.920 445.582 1.00 97.11  ? 109 HIS C CD2 1 
ATOM 6121 C CE1 . HIS E 5 109 ? 278.080 318.500 444.811 1.00 97.11  ? 109 HIS C CE1 1 
ATOM 6122 N NE2 . HIS E 5 109 ? 278.766 318.843 445.885 1.00 97.11  ? 109 HIS C NE2 1 
ATOM 6123 N N   . TRP E 5 110 ? 282.149 323.930 443.506 1.00 93.05  ? 110 TRP C N   1 
ATOM 6124 C CA  . TRP E 5 110 ? 282.897 324.824 442.637 1.00 93.05  ? 110 TRP C CA  1 
ATOM 6125 C C   . TRP E 5 110 ? 284.382 324.527 442.758 1.00 93.05  ? 110 TRP C C   1 
ATOM 6126 O O   . TRP E 5 110 ? 284.852 324.015 443.774 1.00 93.05  ? 110 TRP C O   1 
ATOM 6127 C CB  . TRP E 5 110 ? 282.617 326.287 442.962 1.00 93.05  ? 110 TRP C CB  1 
ATOM 6128 C CG  . TRP E 5 110 ? 282.446 326.545 444.395 1.00 93.05  ? 110 TRP C CG  1 
ATOM 6129 C CD1 . TRP E 5 110 ? 281.282 326.578 445.080 1.00 93.05  ? 110 TRP C CD1 1 
ATOM 6130 C CD2 . TRP E 5 110 ? 283.476 326.831 445.335 1.00 93.05  ? 110 TRP C CD2 1 
ATOM 6131 N NE1 . TRP E 5 110 ? 281.515 326.861 446.399 1.00 93.05  ? 110 TRP C NE1 1 
ATOM 6132 C CE2 . TRP E 5 110 ? 282.861 327.020 446.579 1.00 93.05  ? 110 TRP C CE2 1 
ATOM 6133 C CE3 . TRP E 5 110 ? 284.859 326.943 445.245 1.00 93.05  ? 110 TRP C CE3 1 
ATOM 6134 C CZ2 . TRP E 5 110 ? 283.577 327.311 447.721 1.00 93.05  ? 110 TRP C CZ2 1 
ATOM 6135 C CZ3 . TRP E 5 110 ? 285.567 327.231 446.377 1.00 93.05  ? 110 TRP C CZ3 1 
ATOM 6136 C CH2 . TRP E 5 110 ? 284.929 327.413 447.600 1.00 93.05  ? 110 TRP C CH2 1 
ATOM 6137 N N   . SER E 5 111 ? 285.121 324.866 441.705 1.00 98.64  ? 111 SER C N   1 
ATOM 6138 C CA  . SER E 5 111 ? 286.533 324.523 441.621 1.00 98.64  ? 111 SER C CA  1 
ATOM 6139 C C   . SER E 5 111 ? 287.223 325.465 440.654 1.00 98.64  ? 111 SER C C   1 
ATOM 6140 O O   . SER E 5 111 ? 286.675 325.759 439.590 1.00 98.64  ? 111 SER C O   1 
ATOM 6141 C CB  . SER E 5 111 ? 286.708 323.091 441.145 1.00 98.64  ? 111 SER C CB  1 
ATOM 6142 O OG  . SER E 5 111 ? 286.681 323.048 439.732 1.00 98.64  ? 111 SER C OG  1 
ATOM 6143 N N   . GLY E 5 112 ? 288.423 325.908 441.002 1.00 96.80  ? 112 GLY C N   1 
ATOM 6144 C CA  . GLY E 5 112 ? 289.165 326.784 440.117 1.00 96.80  ? 112 GLY C CA  1 
ATOM 6145 C C   . GLY E 5 112 ? 290.355 327.384 440.827 1.00 96.80  ? 112 GLY C C   1 
ATOM 6146 O O   . GLY E 5 112 ? 290.759 326.922 441.893 1.00 96.80  ? 112 GLY C O   1 
ATOM 6147 N N   . SER E 5 113 ? 290.914 328.423 440.223 1.00 93.16  ? 113 SER C N   1 
ATOM 6148 C CA  . SER E 5 113 ? 292.041 329.140 440.793 1.00 93.16  ? 113 SER C CA  1 
ATOM 6149 C C   . SER E 5 113 ? 291.671 330.601 441.023 1.00 93.16  ? 113 SER C C   1 
ATOM 6150 O O   . SER E 5 113 ? 290.591 331.057 440.656 1.00 93.16  ? 113 SER C O   1 
ATOM 6151 C CB  . SER E 5 113 ? 293.268 329.015 439.897 1.00 93.16  ? 113 SER C CB  1 
ATOM 6152 O OG  . SER E 5 113 ? 292.993 329.548 438.622 1.00 93.16  ? 113 SER C OG  1 
ATOM 6153 N N   . ILE E 5 114 ? 292.586 331.337 441.643 1.00 89.09  ? 114 ILE C N   1 
ATOM 6154 C CA  . ILE E 5 114 ? 292.321 332.677 442.155 1.00 89.09  ? 114 ILE C CA  1 
ATOM 6155 C C   . ILE E 5 114 ? 293.529 333.557 441.880 1.00 89.09  ? 114 ILE C C   1 
ATOM 6156 O O   . ILE E 5 114 ? 294.660 333.164 442.169 1.00 89.09  ? 114 ILE C O   1 
ATOM 6157 C CB  . ILE E 5 114 ? 292.014 332.632 443.664 1.00 89.09  ? 114 ILE C CB  1 
ATOM 6158 C CG1 . ILE E 5 114 ? 290.564 332.263 443.901 1.00 89.09  ? 114 ILE C CG1 1 
ATOM 6159 C CG2 . ILE E 5 114 ? 292.346 333.934 444.366 1.00 89.09  ? 114 ILE C CG2 1 
ATOM 6160 C CD1 . ILE E 5 114 ? 290.223 332.233 445.345 1.00 89.09  ? 114 ILE C CD1 1 
ATOM 6161 N N   . LYS E 5 115 ? 293.299 334.738 441.316 1.00 86.92  ? 115 LYS C N   1 
ATOM 6162 C CA  . LYS E 5 115 ? 294.331 335.760 441.303 1.00 86.92  ? 115 LYS C CA  1 
ATOM 6163 C C   . LYS E 5 115 ? 294.293 336.545 442.603 1.00 86.92  ? 115 LYS C C   1 
ATOM 6164 O O   . LYS E 5 115 ? 293.223 336.900 443.094 1.00 86.92  ? 115 LYS C O   1 
ATOM 6165 C CB  . LYS E 5 115 ? 294.140 336.711 440.130 1.00 86.92  ? 115 LYS C CB  1 
ATOM 6166 C CG  . LYS E 5 115 ? 294.768 336.235 438.844 1.00 86.92  ? 115 LYS C CG  1 
ATOM 6167 C CD  . LYS E 5 115 ? 295.436 337.378 438.105 1.00 86.92  ? 115 LYS C CD  1 
ATOM 6168 C CE  . LYS E 5 115 ? 294.493 338.551 437.918 1.00 86.92  ? 115 LYS C CE  1 
ATOM 6169 N NZ  . LYS E 5 115 ? 295.222 339.773 437.491 1.00 86.92  ? 115 LYS C NZ  1 
ATOM 6170 N N   . LEU E 5 116 ? 295.466 336.814 443.160 1.00 79.57  ? 116 LEU C N   1 
ATOM 6171 C CA  . LEU E 5 116 ? 295.602 337.584 444.392 1.00 79.57  ? 116 LEU C CA  1 
ATOM 6172 C C   . LEU E 5 116 ? 296.535 338.750 444.108 1.00 79.57  ? 116 LEU C C   1 
ATOM 6173 O O   . LEU E 5 116 ? 297.753 338.585 444.080 1.00 79.57  ? 116 LEU C O   1 
ATOM 6174 C CB  . LEU E 5 116 ? 296.127 336.728 445.507 1.00 79.57  ? 116 LEU C CB  1 
ATOM 6175 C CG  . LEU E 5 116 ? 295.103 336.139 446.460 1.00 79.57  ? 116 LEU C CG  1 
ATOM 6176 C CD1 . LEU E 5 116 ? 295.734 335.021 447.234 1.00 79.57  ? 116 LEU C CD1 1 
ATOM 6177 C CD2 . LEU E 5 116 ? 294.622 337.200 447.399 1.00 79.57  ? 116 LEU C CD2 1 
ATOM 6178 N N   . THR E 5 117 ? 295.969 339.930 443.899 1.00 79.07  ? 117 THR C N   1 
ATOM 6179 C CA  . THR E 5 117 ? 296.758 341.118 443.620 1.00 79.07  ? 117 THR C CA  1 
ATOM 6180 C C   . THR E 5 117 ? 296.952 341.904 444.904 1.00 79.07  ? 117 THR C C   1 
ATOM 6181 O O   . THR E 5 117 ? 295.984 342.179 445.617 1.00 79.07  ? 117 THR C O   1 
ATOM 6182 C CB  . THR E 5 117 ? 296.065 341.990 442.575 1.00 79.07  ? 117 THR C CB  1 
ATOM 6183 O OG1 . THR E 5 117 ? 295.915 341.252 441.359 1.00 79.07  ? 117 THR C OG1 1 
ATOM 6184 C CG2 . THR E 5 117 ? 296.870 343.239 442.289 1.00 79.07  ? 117 THR C CG2 1 
ATOM 6185 N N   . PHE E 5 118 ? 298.193 342.253 445.206 1.00 75.66  ? 118 PHE C N   1 
ATOM 6186 C CA  . PHE E 5 118 ? 298.494 343.153 446.304 1.00 75.66  ? 118 PHE C CA  1 
ATOM 6187 C C   . PHE E 5 118 ? 298.903 344.507 445.753 1.00 75.66  ? 118 PHE C C   1 
ATOM 6188 O O   . PHE E 5 118 ? 299.219 344.651 444.573 1.00 75.66  ? 118 PHE C O   1 
ATOM 6189 C CB  . PHE E 5 118 ? 299.592 342.572 447.188 1.00 75.66  ? 118 PHE C CB  1 
ATOM 6190 C CG  . PHE E 5 118 ? 299.166 341.370 447.945 1.00 75.66  ? 118 PHE C CG  1 
ATOM 6191 C CD1 . PHE E 5 118 ? 298.497 341.499 449.137 1.00 75.66  ? 118 PHE C CD1 1 
ATOM 6192 C CD2 . PHE E 5 118 ? 299.421 340.109 447.459 1.00 75.66  ? 118 PHE C CD2 1 
ATOM 6193 C CE1 . PHE E 5 118 ? 298.095 340.392 449.837 1.00 75.66  ? 118 PHE C CE1 1 
ATOM 6194 C CE2 . PHE E 5 118 ? 299.023 338.996 448.157 1.00 75.66  ? 118 PHE C CE2 1 
ATOM 6195 C CZ  . PHE E 5 118 ? 298.361 339.139 449.346 1.00 75.66  ? 118 PHE C CZ  1 
ATOM 6196 N N   . MET E 5 119 ? 298.883 345.515 446.617 1.00 81.96  ? 119 MET C N   1 
ATOM 6197 C CA  . MET E 5 119 ? 299.258 346.856 446.193 1.00 81.96  ? 119 MET C CA  1 
ATOM 6198 C C   . MET E 5 119 ? 299.782 347.622 447.390 1.00 81.96  ? 119 MET C C   1 
ATOM 6199 O O   . MET E 5 119 ? 299.152 347.618 448.448 1.00 81.96  ? 119 MET C O   1 
ATOM 6200 C CB  . MET E 5 119 ? 298.073 347.588 445.575 1.00 81.96  ? 119 MET C CB  1 
ATOM 6201 C CG  . MET E 5 119 ? 298.470 348.796 444.769 1.00 81.96  ? 119 MET C CG  1 
ATOM 6202 S SD  . MET E 5 119 ? 297.140 349.398 443.724 1.00 81.96  ? 119 MET C SD  1 
ATOM 6203 C CE  . MET E 5 119 ? 295.993 349.975 444.961 1.00 81.96  ? 119 MET C CE  1 
ATOM 6204 N N   . PHE E 5 120 ? 300.924 348.274 447.221 1.00 84.52  ? 120 PHE C N   1 
ATOM 6205 C CA  . PHE E 5 120 ? 301.552 349.039 448.289 1.00 84.52  ? 120 PHE C CA  1 
ATOM 6206 C C   . PHE E 5 120 ? 301.076 350.477 448.194 1.00 84.52  ? 120 PHE C C   1 
ATOM 6207 O O   . PHE E 5 120 ? 301.489 351.216 447.298 1.00 84.52  ? 120 PHE C O   1 
ATOM 6208 C CB  . PHE E 5 120 ? 303.067 348.968 448.176 1.00 84.52  ? 120 PHE C CB  1 
ATOM 6209 C CG  . PHE E 5 120 ? 303.792 349.558 449.340 1.00 84.52  ? 120 PHE C CG  1 
ATOM 6210 C CD1 . PHE E 5 120 ? 304.067 348.794 450.450 1.00 84.52  ? 120 PHE C CD1 1 
ATOM 6211 C CD2 . PHE E 5 120 ? 304.230 350.865 449.312 1.00 84.52  ? 120 PHE C CD2 1 
ATOM 6212 C CE1 . PHE E 5 120 ? 304.748 349.324 451.515 1.00 84.52  ? 120 PHE C CE1 1 
ATOM 6213 C CE2 . PHE E 5 120 ? 304.917 351.394 450.376 1.00 84.52  ? 120 PHE C CE2 1 
ATOM 6214 C CZ  . PHE E 5 120 ? 305.172 350.623 451.475 1.00 84.52  ? 120 PHE C CZ  1 
ATOM 6215 N N   . CYS E 5 121 ? 300.219 350.879 449.119 1.00 89.83  ? 121 CYS C N   1 
ATOM 6216 C CA  . CYS E 5 121 ? 299.674 352.230 449.125 1.00 89.83  ? 121 CYS C CA  1 
ATOM 6217 C C   . CYS E 5 121 ? 300.426 353.103 450.123 1.00 89.83  ? 121 CYS C C   1 
ATOM 6218 O O   . CYS E 5 121 ? 299.883 353.569 451.115 1.00 89.83  ? 121 CYS C O   1 
ATOM 6219 C CB  . CYS E 5 121 ? 298.191 352.186 449.443 1.00 89.83  ? 121 CYS C CB  1 
ATOM 6220 S SG  . CYS E 5 121 ? 297.190 351.709 448.040 1.00 89.83  ? 121 CYS C SG  1 
ATOM 6221 N N   . GLY E 5 122 ? 301.702 353.313 449.850 1.00 91.41  ? 122 GLY C N   1 
ATOM 6222 C CA  . GLY E 5 122 ? 302.526 354.072 450.765 1.00 91.41  ? 122 GLY C CA  1 
ATOM 6223 C C   . GLY E 5 122 ? 303.225 355.222 450.084 1.00 91.41  ? 122 GLY C C   1 
ATOM 6224 O O   . GLY E 5 122 ? 302.785 355.675 449.027 1.00 91.41  ? 122 GLY C O   1 
ATOM 6225 N N   . SER E 5 123 ? 304.319 355.700 450.670 1.00 88.46  ? 123 SER C N   1 
ATOM 6226 C CA  . SER E 5 123 ? 305.043 356.824 450.109 1.00 88.46  ? 123 SER C CA  1 
ATOM 6227 C C   . SER E 5 123 ? 305.829 356.402 448.875 1.00 88.46  ? 123 SER C C   1 
ATOM 6228 O O   . SER E 5 123 ? 305.915 355.222 448.528 1.00 88.46  ? 123 SER C O   1 
ATOM 6229 C CB  . SER E 5 123 ? 305.979 357.424 451.144 1.00 88.46  ? 123 SER C CB  1 
ATOM 6230 O OG  . SER E 5 123 ? 306.763 358.436 450.545 1.00 88.46  ? 123 SER C OG  1 
ATOM 6231 N N   . ALA E 5 124 ? 306.418 357.383 448.200 1.00 90.53  ? 124 ALA C N   1 
ATOM 6232 C CA  . ALA E 5 124 ? 307.223 357.121 447.018 1.00 90.53  ? 124 ALA C CA  1 
ATOM 6233 C C   . ALA E 5 124 ? 308.706 357.019 447.322 1.00 90.53  ? 124 ALA C C   1 
ATOM 6234 O O   . ALA E 5 124 ? 309.477 356.644 446.434 1.00 90.53  ? 124 ALA C O   1 
ATOM 6235 C CB  . ALA E 5 124 ? 307.001 358.211 445.968 1.00 90.53  ? 124 ALA C CB  1 
ATOM 6236 N N   . MET E 5 125 ? 309.122 357.341 448.542 1.00 95.19  ? 125 MET C N   1 
ATOM 6237 C CA  . MET E 5 125 ? 310.518 357.265 448.936 1.00 95.19  ? 125 MET C CA  1 
ATOM 6238 C C   . MET E 5 125 ? 310.835 356.045 449.786 1.00 95.19  ? 125 MET C C   1 
ATOM 6239 O O   . MET E 5 125 ? 312.011 355.782 450.044 1.00 95.19  ? 125 MET C O   1 
ATOM 6240 C CB  . MET E 5 125 ? 310.916 358.526 449.707 1.00 95.19  ? 125 MET C CB  1 
ATOM 6241 C CG  . MET E 5 125 ? 310.804 359.795 448.906 1.00 95.19  ? 125 MET C CG  1 
ATOM 6242 S SD  . MET E 5 125 ? 311.923 359.784 447.503 1.00 95.19  ? 125 MET C SD  1 
ATOM 6243 C CE  . MET E 5 125 ? 311.690 361.440 446.877 1.00 95.19  ? 125 MET C CE  1 
ATOM 6244 N N   . ALA E 5 126 ? 309.830 355.296 450.217 1.00 93.21  ? 126 ALA C N   1 
ATOM 6245 C CA  . ALA E 5 126 ? 310.018 354.185 451.136 1.00 93.21  ? 126 ALA C CA  1 
ATOM 6246 C C   . ALA E 5 126 ? 310.271 352.899 450.369 1.00 93.21  ? 126 ALA C C   1 
ATOM 6247 O O   . ALA E 5 126 ? 309.663 352.661 449.325 1.00 93.21  ? 126 ALA C O   1 
ATOM 6248 C CB  . ALA E 5 126 ? 308.799 354.018 452.039 1.00 93.21  ? 126 ALA C CB  1 
ATOM 6249 N N   . THR E 5 127 ? 311.186 352.083 450.882 1.00 92.69  ? 127 THR C N   1 
ATOM 6250 C CA  . THR E 5 127 ? 311.539 350.801 450.294 1.00 92.69  ? 127 THR C CA  1 
ATOM 6251 C C   . THR E 5 127 ? 311.348 349.685 451.311 1.00 92.69  ? 127 THR C C   1 
ATOM 6252 O O   . THR E 5 127 ? 310.977 349.915 452.462 1.00 92.69  ? 127 THR C O   1 
ATOM 6253 C CB  . THR E 5 127 ? 312.986 350.797 449.802 1.00 92.69  ? 127 THR C CB  1 
ATOM 6254 O OG1 . THR E 5 127 ? 313.855 351.028 450.913 1.00 92.69  ? 127 THR C OG1 1 
ATOM 6255 C CG2 . THR E 5 127 ? 313.208 351.875 448.761 1.00 92.69  ? 127 THR C CG2 1 
ATOM 6256 N N   . GLY E 5 128 ? 311.624 348.464 450.874 1.00 87.70  ? 128 GLY C N   1 
ATOM 6257 C CA  . GLY E 5 128 ? 311.489 347.309 451.738 1.00 87.70  ? 128 GLY C CA  1 
ATOM 6258 C C   . GLY E 5 128 ? 311.407 346.045 450.913 1.00 87.70  ? 128 GLY C C   1 
ATOM 6259 O O   . GLY E 5 128 ? 311.511 346.069 449.687 1.00 87.70  ? 128 GLY C O   1 
ATOM 6260 N N   . LYS E 5 129 ? 311.210 344.934 451.613 1.00 85.36  ? 129 LYS C N   1 
ATOM 6261 C CA  . LYS E 5 129 ? 311.066 343.639 450.967 1.00 85.36  ? 129 LYS C CA  1 
ATOM 6262 C C   . LYS E 5 129 ? 310.095 342.785 451.764 1.00 85.36  ? 129 LYS C C   1 
ATOM 6263 O O   . LYS E 5 129 ? 310.063 342.862 452.992 1.00 85.36  ? 129 LYS C O   1 
ATOM 6264 C CB  . LYS E 5 129 ? 312.407 342.924 450.850 1.00 85.36  ? 129 LYS C CB  1 
ATOM 6265 C CG  . LYS E 5 129 ? 313.169 343.231 449.589 1.00 85.36  ? 129 LYS C CG  1 
ATOM 6266 C CD  . LYS E 5 129 ? 314.521 342.566 449.609 1.00 85.36  ? 129 LYS C CD  1 
ATOM 6267 C CE  . LYS E 5 129 ? 315.222 342.725 448.283 1.00 85.36  ? 129 LYS C CE  1 
ATOM 6268 N NZ  . LYS E 5 129 ? 314.565 341.935 447.216 1.00 85.36  ? 129 LYS C NZ  1 
ATOM 6269 N N   . PHE E 5 130 ? 309.314 341.966 451.066 1.00 83.62  ? 130 PHE C N   1 
ATOM 6270 C CA  . PHE E 5 130 ? 308.330 341.107 451.702 1.00 83.62  ? 130 PHE C CA  1 
ATOM 6271 C C   . PHE E 5 130 ? 308.356 339.722 451.080 1.00 83.62  ? 130 PHE C C   1 
ATOM 6272 O O   . PHE E 5 130 ? 308.573 339.570 449.878 1.00 83.62  ? 130 PHE C O   1 
ATOM 6273 C CB  . PHE E 5 130 ? 306.919 341.666 451.571 1.00 83.62  ? 130 PHE C CB  1 
ATOM 6274 C CG  . PHE E 5 130 ? 306.714 342.967 452.265 1.00 83.62  ? 130 PHE C CG  1 
ATOM 6275 C CD1 . PHE E 5 130 ? 306.872 343.066 453.625 1.00 83.62  ? 130 PHE C CD1 1 
ATOM 6276 C CD2 . PHE E 5 130 ? 306.342 344.086 451.559 1.00 83.62  ? 130 PHE C CD2 1 
ATOM 6277 C CE1 . PHE E 5 130 ? 306.678 344.263 454.265 1.00 83.62  ? 130 PHE C CE1 1 
ATOM 6278 C CE2 . PHE E 5 130 ? 306.146 345.280 452.194 1.00 83.62  ? 130 PHE C CE2 1 
ATOM 6279 C CZ  . PHE E 5 130 ? 306.315 345.369 453.547 1.00 83.62  ? 130 PHE C CZ  1 
ATOM 6280 N N   . LEU E 5 131 ? 308.124 338.714 451.911 1.00 83.85  ? 131 LEU C N   1 
ATOM 6281 C CA  . LEU E 5 131 ? 307.870 337.357 451.459 1.00 83.85  ? 131 LEU C CA  1 
ATOM 6282 C C   . LEU E 5 131 ? 306.372 337.140 451.356 1.00 83.85  ? 131 LEU C C   1 
ATOM 6283 O O   . LEU E 5 131 ? 305.599 337.694 452.135 1.00 83.85  ? 131 LEU C O   1 
ATOM 6284 C CB  . LEU E 5 131 ? 308.457 336.332 452.422 1.00 83.85  ? 131 LEU C CB  1 
ATOM 6285 C CG  . LEU E 5 131 ? 309.936 336.023 452.289 1.00 83.85  ? 131 LEU C CG  1 
ATOM 6286 C CD1 . LEU E 5 131 ? 310.312 334.968 453.281 1.00 83.85  ? 131 LEU C CD1 1 
ATOM 6287 C CD2 . LEU E 5 131 ? 310.229 335.550 450.902 1.00 83.85  ? 131 LEU C CD2 1 
ATOM 6288 N N   . LEU E 5 132 ? 305.955 336.331 450.390 1.00 81.29  ? 132 LEU C N   1 
ATOM 6289 C CA  . LEU E 5 132 ? 304.550 335.951 450.264 1.00 81.29  ? 132 LEU C CA  1 
ATOM 6290 C C   . LEU E 5 132 ? 304.501 334.433 450.181 1.00 81.29  ? 132 LEU C C   1 
ATOM 6291 O O   . LEU E 5 132 ? 304.453 333.862 449.092 1.00 81.29  ? 132 LEU C O   1 
ATOM 6292 C CB  . LEU E 5 132 ? 303.916 336.599 449.057 1.00 81.29  ? 132 LEU C CB  1 
ATOM 6293 C CG  . LEU E 5 132 ? 303.808 338.113 449.114 1.00 81.29  ? 132 LEU C CG  1 
ATOM 6294 C CD1 . LEU E 5 132 ? 303.284 338.643 447.812 1.00 81.29  ? 132 LEU C CD1 1 
ATOM 6295 C CD2 . LEU E 5 132 ? 302.899 338.506 450.230 1.00 81.29  ? 132 LEU C CD2 1 
ATOM 6296 N N   . ALA E 5 133 ? 304.503 333.777 451.329 1.00 82.86  ? 133 ALA C N   1 
ATOM 6297 C CA  . ALA E 5 133 ? 304.563 332.329 451.362 1.00 82.86  ? 133 ALA C CA  1 
ATOM 6298 C C   . ALA E 5 133 ? 303.167 331.746 451.282 1.00 82.86  ? 133 ALA C C   1 
ATOM 6299 O O   . ALA E 5 133 ? 302.269 332.160 452.013 1.00 82.86  ? 133 ALA C O   1 
ATOM 6300 C CB  . ALA E 5 133 ? 305.255 331.849 452.634 1.00 82.86  ? 133 ALA C CB  1 
ATOM 6301 N N   . TYR E 5 134 ? 302.992 330.777 450.394 1.00 89.81  ? 134 TYR C N   1 
ATOM 6302 C CA  . TYR E 5 134 ? 301.731 330.068 450.239 1.00 89.81  ? 134 TYR C CA  1 
ATOM 6303 C C   . TYR E 5 134 ? 301.948 328.620 450.640 1.00 89.81  ? 134 TYR C C   1 
ATOM 6304 O O   . TYR E 5 134 ? 302.808 327.944 450.074 1.00 89.81  ? 134 TYR C O   1 
ATOM 6305 C CB  . TYR E 5 134 ? 301.220 330.168 448.804 1.00 89.81  ? 134 TYR C CB  1 
ATOM 6306 C CG  . TYR E 5 134 ? 300.403 328.989 448.341 1.00 89.81  ? 134 TYR C CG  1 
ATOM 6307 C CD1 . TYR E 5 134 ? 299.130 328.760 448.835 1.00 89.81  ? 134 TYR C CD1 1 
ATOM 6308 C CD2 . TYR E 5 134 ? 300.898 328.119 447.386 1.00 89.81  ? 134 TYR C CD2 1 
ATOM 6309 C CE1 . TYR E 5 134 ? 298.390 327.682 448.414 1.00 89.81  ? 134 TYR C CE1 1 
ATOM 6310 C CE2 . TYR E 5 134 ? 300.161 327.046 446.952 1.00 89.81  ? 134 TYR C CE2 1 
ATOM 6311 C CZ  . TYR E 5 134 ? 298.908 326.834 447.468 1.00 89.81  ? 134 TYR C CZ  1 
ATOM 6312 O OH  . TYR E 5 134 ? 298.169 325.762 447.036 1.00 89.81  ? 134 TYR C OH  1 
ATOM 6313 N N   . SER E 5 135 ? 301.175 328.150 451.606 1.00 93.35  ? 135 SER C N   1 
ATOM 6314 C CA  . SER E 5 135 ? 301.368 326.747 451.932 1.00 93.35  ? 135 SER C CA  1 
ATOM 6315 C C   . SER E 5 135 ? 300.291 325.896 451.281 1.00 93.35  ? 135 SER C C   1 
ATOM 6316 O O   . SER E 5 135 ? 299.127 326.294 451.248 1.00 93.35  ? 135 SER C O   1 
ATOM 6317 C CB  . SER E 5 135 ? 301.334 326.534 453.439 1.00 93.35  ? 135 SER C CB  1 
ATOM 6318 O OG  . SER E 5 135 ? 302.223 327.429 454.068 1.00 93.35  ? 135 SER C OG  1 
ATOM 6319 N N   . PRO E 5 136 ? 300.646 324.729 450.755 1.00 98.31  ? 136 PRO C N   1 
ATOM 6320 C CA  . PRO E 5 136 ? 299.665 323.882 450.083 1.00 98.31  ? 136 PRO C CA  1 
ATOM 6321 C C   . PRO E 5 136 ? 298.730 323.243 451.092 1.00 98.31  ? 136 PRO C C   1 
ATOM 6322 O O   . PRO E 5 136 ? 299.025 323.249 452.296 1.00 98.31  ? 136 PRO C O   1 
ATOM 6323 C CB  . PRO E 5 136 ? 300.540 322.830 449.385 1.00 98.31  ? 136 PRO C CB  1 
ATOM 6324 C CG  . PRO E 5 136 ? 301.914 323.386 449.405 1.00 98.31  ? 136 PRO C CG  1 
ATOM 6325 C CD  . PRO E 5 136 ? 301.996 324.168 450.657 1.00 98.31  ? 136 PRO C CD  1 
ATOM 6326 N N   . PRO E 5 137 ? 297.584 322.713 450.657 1.00 100.57 ? 137 PRO C N   1 
ATOM 6327 C CA  . PRO E 5 137 ? 296.695 322.009 451.592 1.00 100.57 ? 137 PRO C CA  1 
ATOM 6328 C C   . PRO E 5 137 ? 297.341 320.730 452.092 1.00 100.57 ? 137 PRO C C   1 
ATOM 6329 O O   . PRO E 5 137 ? 297.804 319.905 451.306 1.00 100.57 ? 137 PRO C O   1 
ATOM 6330 C CB  . PRO E 5 137 ? 295.450 321.719 450.749 1.00 100.57 ? 137 PRO C CB  1 
ATOM 6331 C CG  . PRO E 5 137 ? 295.910 321.801 449.352 1.00 100.57 ? 137 PRO C CG  1 
ATOM 6332 C CD  . PRO E 5 137 ? 296.944 322.871 449.342 1.00 100.57 ? 137 PRO C CD  1 
ATOM 6333 N N   . GLY E 5 138 ? 297.384 320.577 453.407 1.00 103.98 ? 138 GLY C N   1 
ATOM 6334 C CA  . GLY E 5 138 ? 298.012 319.420 454.003 1.00 103.98 ? 138 GLY C CA  1 
ATOM 6335 C C   . GLY E 5 138 ? 299.211 319.801 454.836 1.00 103.98 ? 138 GLY C C   1 
ATOM 6336 O O   . GLY E 5 138 ? 299.387 319.296 455.947 1.00 103.98 ? 138 GLY C O   1 
ATOM 6337 N N   . ALA E 5 139 ? 300.041 320.698 454.321 1.00 106.05 ? 139 ALA C N   1 
ATOM 6338 C CA  . ALA E 5 139 ? 301.176 321.178 455.087 1.00 106.05 ? 139 ALA C CA  1 
ATOM 6339 C C   . ALA E 5 139 ? 300.716 322.206 456.108 1.00 106.05 ? 139 ALA C C   1 
ATOM 6340 O O   . ALA E 5 139 ? 299.698 322.877 455.931 1.00 106.05 ? 139 ALA C O   1 
ATOM 6341 C CB  . ALA E 5 139 ? 302.235 321.786 454.169 1.00 106.05 ? 139 ALA C CB  1 
ATOM 6342 N N   . GLY E 5 140 ? 301.474 322.320 457.186 1.00 105.09 ? 140 GLY C N   1 
ATOM 6343 C CA  . GLY E 5 140 ? 301.115 323.236 458.242 1.00 105.09 ? 140 GLY C CA  1 
ATOM 6344 C C   . GLY E 5 140 ? 301.423 324.675 457.895 1.00 105.09 ? 140 GLY C C   1 
ATOM 6345 O O   . GLY E 5 140 ? 302.057 324.987 456.890 1.00 105.09 ? 140 GLY C O   1 
ATOM 6346 N N   . VAL E 5 141 ? 300.947 325.568 458.752 1.00 100.99 ? 141 VAL C N   1 
ATOM 6347 C CA  . VAL E 5 141 ? 301.241 326.991 458.629 1.00 100.99 ? 141 VAL C CA  1 
ATOM 6348 C C   . VAL E 5 141 ? 302.692 327.199 459.050 1.00 100.99 ? 141 VAL C C   1 
ATOM 6349 O O   . VAL E 5 141 ? 303.155 326.564 460.008 1.00 100.99 ? 141 VAL C O   1 
ATOM 6350 C CB  . VAL E 5 141 ? 300.229 327.823 459.440 1.00 100.99 ? 141 VAL C CB  1 
ATOM 6351 C CG1 . VAL E 5 141 ? 300.196 327.405 460.903 1.00 100.99 ? 141 VAL C CG1 1 
ATOM 6352 C CG2 . VAL E 5 141 ? 300.507 329.308 459.320 1.00 100.99 ? 141 VAL C CG2 1 
ATOM 6353 N N   . PRO E 5 142 ? 303.475 327.998 458.323 1.00 97.89  ? 142 PRO C N   1 
ATOM 6354 C CA  . PRO E 5 142 ? 304.867 328.219 458.727 1.00 97.89  ? 142 PRO C CA  1 
ATOM 6355 C C   . PRO E 5 142 ? 304.939 329.094 459.966 1.00 97.89  ? 142 PRO C C   1 
ATOM 6356 O O   . PRO E 5 142 ? 304.312 330.150 460.032 1.00 97.89  ? 142 PRO C O   1 
ATOM 6357 C CB  . PRO E 5 142 ? 305.485 328.914 457.511 1.00 97.89  ? 142 PRO C CB  1 
ATOM 6358 C CG  . PRO E 5 142 ? 304.341 329.474 456.775 1.00 97.89  ? 142 PRO C CG  1 
ATOM 6359 C CD  . PRO E 5 142 ? 303.216 328.525 456.978 1.00 97.89  ? 142 PRO C CD  1 
ATOM 6360 N N   . LYS E 5 143 ? 305.704 328.642 460.951 1.00 101.64 ? 143 LYS C N   1 
ATOM 6361 C CA  . LYS E 5 143 ? 305.819 329.341 462.219 1.00 101.64 ? 143 LYS C CA  1 
ATOM 6362 C C   . LYS E 5 143 ? 307.099 330.150 462.328 1.00 101.64 ? 143 LYS C C   1 
ATOM 6363 O O   . LYS E 5 143 ? 307.447 330.592 463.425 1.00 101.64 ? 143 LYS C O   1 
ATOM 6364 C CB  . LYS E 5 143 ? 305.742 328.347 463.372 1.00 101.64 ? 143 LYS C CB  1 
ATOM 6365 C CG  . LYS E 5 143 ? 306.733 327.202 463.257 1.00 101.64 ? 143 LYS C CG  1 
ATOM 6366 C CD  . LYS E 5 143 ? 306.780 326.343 464.520 1.00 101.64 ? 143 LYS C CD  1 
ATOM 6367 C CE  . LYS E 5 143 ? 305.398 326.002 465.072 1.00 101.64 ? 143 LYS C CE  1 
ATOM 6368 N NZ  . LYS E 5 143 ? 304.517 325.313 464.083 1.00 101.64 ? 143 LYS C NZ  1 
ATOM 6369 N N   . ASN E 5 144 ? 307.801 330.358 461.221 1.00 101.43 ? 144 ASN C N   1 
ATOM 6370 C CA  . ASN E 5 144 ? 309.082 331.042 461.249 1.00 101.43 ? 144 ASN C CA  1 
ATOM 6371 C C   . ASN E 5 144 ? 309.346 331.599 459.864 1.00 101.43 ? 144 ASN C C   1 
ATOM 6372 O O   . ASN E 5 144 ? 308.704 331.193 458.896 1.00 101.43 ? 144 ASN C O   1 
ATOM 6373 C CB  . ASN E 5 144 ? 310.198 330.091 461.671 1.00 101.43 ? 144 ASN C CB  1 
ATOM 6374 C CG  . ASN E 5 144 ? 311.389 330.812 462.212 1.00 101.43 ? 144 ASN C CG  1 
ATOM 6375 O OD1 . ASN E 5 144 ? 311.429 332.041 462.214 1.00 101.43 ? 144 ASN C OD1 1 
ATOM 6376 N ND2 . ASN E 5 144 ? 312.376 330.061 462.674 1.00 101.43 ? 144 ASN C ND2 1 
ATOM 6377 N N   . ARG E 5 145 ? 310.285 332.538 459.771 1.00 98.05  ? 145 ARG C N   1 
ATOM 6378 C CA  . ARG E 5 145 ? 310.605 333.081 458.458 1.00 98.05  ? 145 ARG C CA  1 
ATOM 6379 C C   . ARG E 5 145 ? 311.380 332.082 457.617 1.00 98.05  ? 145 ARG C C   1 
ATOM 6380 O O   . ARG E 5 145 ? 311.216 332.049 456.394 1.00 98.05  ? 145 ARG C O   1 
ATOM 6381 C CB  . ARG E 5 145 ? 311.398 334.375 458.585 1.00 98.05  ? 145 ARG C CB  1 
ATOM 6382 C CG  . ARG E 5 145 ? 311.447 335.174 457.303 1.00 98.05  ? 145 ARG C CG  1 
ATOM 6383 C CD  . ARG E 5 145 ? 312.663 336.061 457.254 1.00 98.05  ? 145 ARG C CD  1 
ATOM 6384 N NE  . ARG E 5 145 ? 313.900 335.299 457.186 1.00 98.05  ? 145 ARG C NE  1 
ATOM 6385 C CZ  . ARG E 5 145 ? 314.464 334.905 456.054 1.00 98.05  ? 145 ARG C CZ  1 
ATOM 6386 N NH1 . ARG E 5 145 ? 315.593 334.215 456.074 1.00 98.05  ? 145 ARG C NH1 1 
ATOM 6387 N NH2 . ARG E 5 145 ? 313.894 335.200 454.899 1.00 98.05  ? 145 ARG C NH2 1 
ATOM 6388 N N   . LYS E 5 146 ? 312.203 331.248 458.251 1.00 101.39 ? 146 LYS C N   1 
ATOM 6389 C CA  . LYS E 5 146 ? 313.078 330.360 457.500 1.00 101.39 ? 146 LYS C CA  1 
ATOM 6390 C C   . LYS E 5 146 ? 312.291 329.239 456.841 1.00 101.39 ? 146 LYS C C   1 
ATOM 6391 O O   . LYS E 5 146 ? 312.466 328.968 455.650 1.00 101.39 ? 146 LYS C O   1 
ATOM 6392 C CB  . LYS E 5 146 ? 314.160 329.793 458.408 1.00 101.39 ? 146 LYS C CB  1 
ATOM 6393 C CG  . LYS E 5 146 ? 315.107 328.870 457.691 1.00 101.39 ? 146 LYS C CG  1 
ATOM 6394 C CD  . LYS E 5 146 ? 316.154 328.328 458.633 1.00 101.39 ? 146 LYS C CD  1 
ATOM 6395 C CE  . LYS E 5 146 ? 316.977 327.245 457.972 1.00 101.39 ? 146 LYS C CE  1 
ATOM 6396 N NZ  . LYS E 5 146 ? 317.969 326.676 458.916 1.00 101.39 ? 146 LYS C NZ  1 
ATOM 6397 N N   . ASP E 5 147 ? 311.396 328.593 457.581 1.00 105.36 ? 147 ASP C N   1 
ATOM 6398 C CA  . ASP E 5 147 ? 310.593 327.555 456.952 1.00 105.36 ? 147 ASP C CA  1 
ATOM 6399 C C   . ASP E 5 147 ? 309.423 328.105 456.153 1.00 105.36 ? 147 ASP C C   1 
ATOM 6400 O O   . ASP E 5 147 ? 308.687 327.321 455.553 1.00 105.36 ? 147 ASP C O   1 
ATOM 6401 C CB  . ASP E 5 147 ? 310.121 326.526 457.986 1.00 105.36 ? 147 ASP C CB  1 
ATOM 6402 C CG  . ASP E 5 147 ? 309.274 327.122 459.091 1.00 105.36 ? 147 ASP C CG  1 
ATOM 6403 O OD1 . ASP E 5 147 ? 309.039 328.344 459.116 1.00 105.36 ? 147 ASP C OD1 1 
ATOM 6404 O OD2 . ASP E 5 147 ? 308.878 326.352 459.990 1.00 105.36 ? 147 ASP C OD2 1 
ATOM 6405 N N   . ALA E 5 148 ? 309.219 329.419 456.148 1.00 97.95  ? 148 ALA C N   1 
ATOM 6406 C CA  . ALA E 5 148 ? 308.384 330.023 455.124 1.00 97.95  ? 148 ALA C CA  1 
ATOM 6407 C C   . ALA E 5 148 ? 309.155 330.259 453.844 1.00 97.95  ? 148 ALA C C   1 
ATOM 6408 O O   . ALA E 5 148 ? 308.552 330.310 452.771 1.00 97.95  ? 148 ALA C O   1 
ATOM 6409 C CB  . ALA E 5 148 ? 307.799 331.342 455.615 1.00 97.95  ? 148 ALA C CB  1 
ATOM 6410 N N   . MET E 5 149 ? 310.474 330.400 453.935 1.00 100.89 ? 149 MET C N   1 
ATOM 6411 C CA  . MET E 5 149 ? 311.299 330.563 452.748 1.00 100.89 ? 149 MET C CA  1 
ATOM 6412 C C   . MET E 5 149 ? 311.496 329.246 452.014 1.00 100.89 ? 149 MET C C   1 
ATOM 6413 O O   . MET E 5 149 ? 311.680 329.242 450.793 1.00 100.89 ? 149 MET C O   1 
ATOM 6414 C CB  . MET E 5 149 ? 312.649 331.161 453.139 1.00 100.89 ? 149 MET C CB  1 
ATOM 6415 C CG  . MET E 5 149 ? 313.475 331.675 451.993 1.00 100.89 ? 149 MET C CG  1 
ATOM 6416 S SD  . MET E 5 149 ? 314.729 330.489 451.510 1.00 100.89 ? 149 MET C SD  1 
ATOM 6417 C CE  . MET E 5 149 ? 315.428 330.088 453.101 1.00 100.89 ? 149 MET C CE  1 
ATOM 6418 N N   . LEU E 5 150 ? 311.458 328.125 452.729 1.00 99.40  ? 150 LEU C N   1 
ATOM 6419 C CA  . LEU E 5 150 ? 311.660 326.834 452.090 1.00 99.40  ? 150 LEU C CA  1 
ATOM 6420 C C   . LEU E 5 150 ? 310.446 326.377 451.302 1.00 99.40  ? 150 LEU C C   1 
ATOM 6421 O O   . LEU E 5 150 ? 310.602 325.646 450.322 1.00 99.40  ? 150 LEU C O   1 
ATOM 6422 C CB  . LEU E 5 150 ? 312.029 325.788 453.135 1.00 99.40  ? 150 LEU C CB  1 
ATOM 6423 C CG  . LEU E 5 150 ? 313.240 326.175 453.975 1.00 99.40  ? 150 LEU C CG  1 
ATOM 6424 C CD1 . LEU E 5 150 ? 313.554 325.100 454.985 1.00 99.40  ? 150 LEU C CD1 1 
ATOM 6425 C CD2 . LEU E 5 150 ? 314.435 326.432 453.093 1.00 99.40  ? 150 LEU C CD2 1 
ATOM 6426 N N   . GLY E 5 151 ? 309.247 326.801 451.689 1.00 97.66  ? 151 GLY C N   1 
ATOM 6427 C CA  . GLY E 5 151 ? 308.066 326.547 450.894 1.00 97.66  ? 151 GLY C CA  1 
ATOM 6428 C C   . GLY E 5 151 ? 308.023 327.452 449.686 1.00 97.66  ? 151 GLY C C   1 
ATOM 6429 O O   . GLY E 5 151 ? 308.904 328.276 449.456 1.00 97.66  ? 151 GLY C O   1 
ATOM 6430 N N   . THR E 5 152 ? 306.975 327.292 448.886 1.00 89.99  ? 152 THR C N   1 
ATOM 6431 C CA  . THR E 5 152 ? 306.846 328.124 447.701 1.00 89.99  ? 152 THR C CA  1 
ATOM 6432 C C   . THR E 5 152 ? 306.474 329.547 448.089 1.00 89.99  ? 152 THR C C   1 
ATOM 6433 O O   . THR E 5 152 ? 305.627 329.774 448.953 1.00 89.99  ? 152 THR C O   1 
ATOM 6434 C CB  . THR E 5 152 ? 305.824 327.537 446.735 1.00 89.99  ? 152 THR C CB  1 
ATOM 6435 O OG1 . THR E 5 152 ? 305.470 328.524 445.762 1.00 89.99  ? 152 THR C OG1 1 
ATOM 6436 C CG2 . THR E 5 152 ? 304.599 327.057 447.458 1.00 89.99  ? 152 THR C CG2 1 
ATOM 6437 N N   . HIS E 5 153 ? 307.139 330.510 447.464 1.00 84.24  ? 153 HIS C N   1 
ATOM 6438 C CA  . HIS E 5 153 ? 307.043 331.893 447.897 1.00 84.24  ? 153 HIS C CA  1 
ATOM 6439 C C   . HIS E 5 153 ? 307.413 332.805 446.744 1.00 84.24  ? 153 HIS C C   1 
ATOM 6440 O O   . HIS E 5 153 ? 307.953 332.370 445.729 1.00 84.24  ? 153 HIS C O   1 
ATOM 6441 C CB  . HIS E 5 153 ? 307.957 332.161 449.084 1.00 84.24  ? 153 HIS C CB  1 
ATOM 6442 C CG  . HIS E 5 153 ? 309.409 332.056 448.753 1.00 84.24  ? 153 HIS C CG  1 
ATOM 6443 N ND1 . HIS E 5 153 ? 310.188 333.153 448.469 1.00 84.24  ? 153 HIS C ND1 1 
ATOM 6444 C CD2 . HIS E 5 153 ? 310.225 330.983 448.660 1.00 84.24  ? 153 HIS C CD2 1 
ATOM 6445 C CE1 . HIS E 5 153 ? 311.424 332.761 448.218 1.00 84.24  ? 153 HIS C CE1 1 
ATOM 6446 N NE2 . HIS E 5 153 ? 311.473 331.448 448.328 1.00 84.24  ? 153 HIS C NE2 1 
ATOM 6447 N N   . VAL E 5 154 ? 307.110 334.088 446.921 1.00 80.61  ? 154 VAL C N   1 
ATOM 6448 C CA  . VAL E 5 154 ? 307.466 335.138 445.977 1.00 80.61  ? 154 VAL C CA  1 
ATOM 6449 C C   . VAL E 5 154 ? 307.974 336.309 446.795 1.00 80.61  ? 154 VAL C C   1 
ATOM 6450 O O   . VAL E 5 154 ? 307.254 336.816 447.659 1.00 80.61  ? 154 VAL C O   1 
ATOM 6451 C CB  . VAL E 5 154 ? 306.275 335.576 445.110 1.00 80.61  ? 154 VAL C CB  1 
ATOM 6452 C CG1 . VAL E 5 154 ? 306.564 336.895 444.435 1.00 80.61  ? 154 VAL C CG1 1 
ATOM 6453 C CG2 . VAL E 5 154 ? 305.957 334.527 444.073 1.00 80.61  ? 154 VAL C CG2 1 
ATOM 6454 N N   . ILE E 5 155 ? 309.209 336.726 446.551 1.00 83.55  ? 155 ILE C N   1 
ATOM 6455 C CA  . ILE E 5 155 ? 309.794 337.851 447.268 1.00 83.55  ? 155 ILE C CA  1 
ATOM 6456 C C   . ILE E 5 155 ? 309.422 339.138 446.545 1.00 83.55  ? 155 ILE C C   1 
ATOM 6457 O O   . ILE E 5 155 ? 309.656 339.281 445.342 1.00 83.55  ? 155 ILE C O   1 
ATOM 6458 C CB  . ILE E 5 155 ? 311.314 337.693 447.409 1.00 83.55  ? 155 ILE C CB  1 
ATOM 6459 C CG1 . ILE E 5 155 ? 311.950 339.006 447.824 1.00 83.55  ? 155 ILE C CG1 1 
ATOM 6460 C CG2 . ILE E 5 155 ? 311.934 337.121 446.156 1.00 83.55  ? 155 ILE C CG2 1 
ATOM 6461 C CD1 . ILE E 5 155 ? 313.374 338.860 448.206 1.00 83.55  ? 155 ILE C CD1 1 
ATOM 6462 N N   . TRP E 5 156 ? 308.822 340.070 447.274 1.00 83.23  ? 156 TRP C N   1 
ATOM 6463 C CA  . TRP E 5 156 ? 308.202 341.254 446.695 1.00 83.23  ? 156 TRP C CA  1 
ATOM 6464 C C   . TRP E 5 156 ? 308.999 342.471 447.124 1.00 83.23  ? 156 TRP C C   1 
ATOM 6465 O O   . TRP E 5 156 ? 308.987 342.842 448.300 1.00 83.23  ? 156 TRP C O   1 
ATOM 6466 C CB  . TRP E 5 156 ? 306.748 341.362 447.144 1.00 83.23  ? 156 TRP C CB  1 
ATOM 6467 C CG  . TRP E 5 156 ? 306.027 342.554 446.638 1.00 83.23  ? 156 TRP C CG  1 
ATOM 6468 C CD1 . TRP E 5 156 ? 306.248 343.213 445.475 1.00 83.23  ? 156 TRP C CD1 1 
ATOM 6469 C CD2 . TRP E 5 156 ? 304.952 343.230 447.285 1.00 83.23  ? 156 TRP C CD2 1 
ATOM 6470 N NE1 . TRP E 5 156 ? 305.379 344.264 445.358 1.00 83.23  ? 156 TRP C NE1 1 
ATOM 6471 C CE2 . TRP E 5 156 ? 304.574 344.295 446.460 1.00 83.23  ? 156 TRP C CE2 1 
ATOM 6472 C CE3 . TRP E 5 156 ? 304.275 343.039 448.486 1.00 83.23  ? 156 TRP C CE3 1 
ATOM 6473 C CZ2 . TRP E 5 156 ? 303.557 345.160 446.793 1.00 83.23  ? 156 TRP C CZ2 1 
ATOM 6474 C CZ3 . TRP E 5 156 ? 303.269 343.897 448.812 1.00 83.23  ? 156 TRP C CZ3 1 
ATOM 6475 C CH2 . TRP E 5 156 ? 302.917 344.944 447.972 1.00 83.23  ? 156 TRP C CH2 1 
ATOM 6476 N N   . ASP E 5 157 ? 309.681 343.095 446.175 1.00 90.03  ? 157 ASP C N   1 
ATOM 6477 C CA  . ASP E 5 157 ? 310.440 344.302 446.450 1.00 90.03  ? 157 ASP C CA  1 
ATOM 6478 C C   . ASP E 5 157 ? 309.526 345.490 446.198 1.00 90.03  ? 157 ASP C C   1 
ATOM 6479 O O   . ASP E 5 157 ? 308.896 345.582 445.142 1.00 90.03  ? 157 ASP C O   1 
ATOM 6480 C CB  . ASP E 5 157 ? 311.692 344.369 445.578 1.00 90.03  ? 157 ASP C CB  1 
ATOM 6481 C CG  . ASP E 5 157 ? 312.704 345.401 446.064 1.00 90.03  ? 157 ASP C CG  1 
ATOM 6482 O OD1 . ASP E 5 157 ? 312.336 346.545 446.400 1.00 90.03  ? 157 ASP C OD1 1 
ATOM 6483 O OD2 . ASP E 5 157 ? 313.901 345.053 446.123 1.00 90.03  ? 157 ASP C OD2 1 
ATOM 6484 N N   . VAL E 5 158 ? 309.464 346.400 447.162 1.00 86.59  ? 158 VAL C N   1 
ATOM 6485 C CA  . VAL E 5 158 ? 308.532 347.513 447.076 1.00 86.59  ? 158 VAL C CA  1 
ATOM 6486 C C   . VAL E 5 158 ? 309.117 348.641 446.242 1.00 86.59  ? 158 VAL C C   1 
ATOM 6487 O O   . VAL E 5 158 ? 308.391 349.347 445.534 1.00 86.59  ? 158 VAL C O   1 
ATOM 6488 C CB  . VAL E 5 158 ? 308.168 347.962 448.499 1.00 86.59  ? 158 VAL C CB  1 
ATOM 6489 C CG1 . VAL E 5 158 ? 307.180 349.070 448.480 1.00 86.59  ? 158 VAL C CG1 1 
ATOM 6490 C CG2 . VAL E 5 158 ? 307.600 346.808 449.257 1.00 86.59  ? 158 VAL C CG2 1 
ATOM 6491 N N   . GLY E 5 159 ? 310.439 348.808 446.277 1.00 91.13  ? 159 GLY C N   1 
ATOM 6492 C CA  . GLY E 5 159 ? 311.076 349.918 445.591 1.00 91.13  ? 159 GLY C CA  1 
ATOM 6493 C C   . GLY E 5 159 ? 311.012 349.851 444.079 1.00 91.13  ? 159 GLY C C   1 
ATOM 6494 O O   . GLY E 5 159 ? 310.939 350.896 443.429 1.00 91.13  ? 159 GLY C O   1 
ATOM 6495 N N   . LEU E 5 160 ? 311.023 348.651 443.504 1.00 93.25  ? 160 LEU C N   1 
ATOM 6496 C CA  . LEU E 5 160 ? 310.940 348.526 442.055 1.00 93.25  ? 160 LEU C CA  1 
ATOM 6497 C C   . LEU E 5 160 ? 309.494 348.577 441.583 1.00 93.25  ? 160 LEU C C   1 
ATOM 6498 O O   . LEU E 5 160 ? 309.108 349.477 440.834 1.00 93.25  ? 160 LEU C O   1 
ATOM 6499 C CB  . LEU E 5 160 ? 311.593 347.223 441.594 1.00 93.25  ? 160 LEU C CB  1 
ATOM 6500 C CG  . LEU E 5 160 ? 312.978 346.900 442.137 1.00 93.25  ? 160 LEU C CG  1 
ATOM 6501 C CD1 . LEU E 5 160 ? 313.475 345.605 441.538 1.00 93.25  ? 160 LEU C CD1 1 
ATOM 6502 C CD2 . LEU E 5 160 ? 313.934 348.026 441.832 1.00 93.25  ? 160 LEU C CD2 1 
ATOM 6503 N N   . GLN E 5 161 ? 308.684 347.625 442.026 1.00 91.93  ? 161 GLN C N   1 
ATOM 6504 C CA  . GLN E 5 161 ? 307.295 347.524 441.620 1.00 91.93  ? 161 GLN C CA  1 
ATOM 6505 C C   . GLN E 5 161 ? 306.403 347.685 442.837 1.00 91.93  ? 161 GLN C C   1 
ATOM 6506 O O   . GLN E 5 161 ? 306.831 347.463 443.969 1.00 91.93  ? 161 GLN C O   1 
ATOM 6507 C CB  . GLN E 5 161 ? 307.016 346.187 440.957 1.00 91.93  ? 161 GLN C CB  1 
ATOM 6508 C CG  . GLN E 5 161 ? 307.466 345.021 441.790 1.00 91.93  ? 161 GLN C CG  1 
ATOM 6509 C CD  . GLN E 5 161 ? 307.434 343.729 441.022 1.00 91.93  ? 161 GLN C CD  1 
ATOM 6510 O OE1 . GLN E 5 161 ? 306.972 343.686 439.885 1.00 91.93  ? 161 GLN C OE1 1 
ATOM 6511 N NE2 . GLN E 5 161 ? 307.925 342.663 441.636 1.00 91.93  ? 161 GLN C NE2 1 
ATOM 6512 N N   . SER E 5 162 ? 305.155 348.070 442.595 1.00 89.02  ? 162 SER C N   1 
ATOM 6513 C CA  . SER E 5 162 ? 304.211 348.313 443.671 1.00 89.02  ? 162 SER C CA  1 
ATOM 6514 C C   . SER E 5 162 ? 302.977 347.431 443.585 1.00 89.02  ? 162 SER C C   1 
ATOM 6515 O O   . SER E 5 162 ? 301.956 347.759 444.190 1.00 89.02  ? 162 SER C O   1 
ATOM 6516 C CB  . SER E 5 162 ? 303.800 349.779 443.677 1.00 89.02  ? 162 SER C CB  1 
ATOM 6517 O OG  . SER E 5 162 ? 303.397 350.173 442.383 1.00 89.02  ? 162 SER C OG  1 
ATOM 6518 N N   . SER E 5 163 ? 303.041 346.325 442.850 1.00 90.77  ? 163 SER C N   1 
ATOM 6519 C CA  . SER E 5 163 ? 301.911 345.414 442.745 1.00 90.77  ? 163 SER C CA  1 
ATOM 6520 C C   . SER E 5 163 ? 302.421 344.032 442.385 1.00 90.77  ? 163 SER C C   1 
ATOM 6521 O O   . SER E 5 163 ? 303.038 343.858 441.334 1.00 90.77  ? 163 SER C O   1 
ATOM 6522 C CB  . SER E 5 163 ? 300.922 345.885 441.686 1.00 90.77  ? 163 SER C CB  1 
ATOM 6523 O OG  . SER E 5 163 ? 301.323 345.420 440.414 1.00 90.77  ? 163 SER C OG  1 
ATOM 6524 N N   . CYS E 5 164 ? 302.146 343.053 443.236 1.00 87.62  ? 164 CYS C N   1 
ATOM 6525 C CA  . CYS E 5 164 ? 302.639 341.697 443.053 1.00 87.62  ? 164 CYS C CA  1 
ATOM 6526 C C   . CYS E 5 164 ? 301.464 340.745 442.920 1.00 87.62  ? 164 CYS C C   1 
ATOM 6527 O O   . CYS E 5 164 ? 300.606 340.690 443.802 1.00 87.62  ? 164 CYS C O   1 
ATOM 6528 C CB  . CYS E 5 164 ? 303.522 341.276 444.219 1.00 87.62  ? 164 CYS C CB  1 
ATOM 6529 S SG  . CYS E 5 164 ? 303.817 339.516 444.291 1.00 87.62  ? 164 CYS C SG  1 
ATOM 6530 N N   . VAL E 5 165 ? 301.442 339.985 441.830 1.00 85.53  ? 165 VAL C N   1 
ATOM 6531 C CA  . VAL E 5 165 ? 300.320 339.126 441.475 1.00 85.53  ? 165 VAL C CA  1 
ATOM 6532 C C   . VAL E 5 165 ? 300.687 337.686 441.791 1.00 85.53  ? 165 VAL C C   1 
ATOM 6533 O O   . VAL E 5 165 ? 301.767 337.217 441.423 1.00 85.53  ? 165 VAL C O   1 
ATOM 6534 C CB  . VAL E 5 165 ? 299.958 339.296 439.988 1.00 85.53  ? 165 VAL C CB  1 
ATOM 6535 C CG1 . VAL E 5 165 ? 298.898 338.304 439.563 1.00 85.53  ? 165 VAL C CG1 1 
ATOM 6536 C CG2 . VAL E 5 165 ? 299.492 340.708 439.726 1.00 85.53  ? 165 VAL C CG2 1 
ATOM 6537 N N   . LEU E 5 166 ? 299.787 336.986 442.475 1.00 86.85  ? 166 LEU C N   1 
ATOM 6538 C CA  . LEU E 5 166 ? 300.008 335.611 442.892 1.00 86.85  ? 166 LEU C CA  1 
ATOM 6539 C C   . LEU E 5 166 ? 298.775 334.792 442.544 1.00 86.85  ? 166 LEU C C   1 
ATOM 6540 O O   . LEU E 5 166 ? 297.663 335.172 442.916 1.00 86.85  ? 166 LEU C O   1 
ATOM 6541 C CB  . LEU E 5 166 ? 300.295 335.562 444.394 1.00 86.85  ? 166 LEU C CB  1 
ATOM 6542 C CG  . LEU E 5 166 ? 300.570 334.235 445.083 1.00 86.85  ? 166 LEU C CG  1 
ATOM 6543 C CD1 . LEU E 5 166 ? 301.704 333.520 444.402 1.00 86.85  ? 166 LEU C CD1 1 
ATOM 6544 C CD2 . LEU E 5 166 ? 300.908 334.487 446.529 1.00 86.85  ? 166 LEU C CD2 1 
ATOM 6545 N N   . CYS E 5 167 ? 298.960 333.688 441.825 1.00 91.03  ? 167 CYS C N   1 
ATOM 6546 C CA  . CYS E 5 167 ? 297.854 332.838 441.397 1.00 91.03  ? 167 CYS C CA  1 
ATOM 6547 C C   . CYS E 5 167 ? 297.847 331.537 442.189 1.00 91.03  ? 167 CYS C C   1 
ATOM 6548 O O   . CYS E 5 167 ? 298.896 330.927 442.400 1.00 91.03  ? 167 CYS C O   1 
ATOM 6549 C CB  . CYS E 5 167 ? 297.948 332.538 439.904 1.00 91.03  ? 167 CYS C CB  1 
ATOM 6550 S SG  . CYS E 5 167 ? 296.859 331.225 439.345 1.00 91.03  ? 167 CYS C SG  1 
ATOM 6551 N N   . VAL E 5 168 ? 296.663 331.100 442.605 1.00 90.31  ? 168 VAL C N   1 
ATOM 6552 C CA  . VAL E 5 168 ? 296.553 330.019 443.583 1.00 90.31  ? 168 VAL C CA  1 
ATOM 6553 C C   . VAL E 5 168 ? 295.217 329.285 443.463 1.00 90.31  ? 168 VAL C C   1 
ATOM 6554 O O   . VAL E 5 168 ? 294.169 329.927 443.316 1.00 90.31  ? 168 VAL C O   1 
ATOM 6555 C CB  . VAL E 5 168 ? 296.793 330.575 444.997 1.00 90.31  ? 168 VAL C CB  1 
ATOM 6556 C CG1 . VAL E 5 168 ? 295.931 331.776 445.264 1.00 90.31  ? 168 VAL C CG1 1 
ATOM 6557 C CG2 . VAL E 5 168 ? 296.508 329.541 446.036 1.00 90.31  ? 168 VAL C CG2 1 
ATOM 6558 N N   . PRO E 5 169 ? 295.207 327.949 443.459 1.00 94.30  ? 169 PRO C N   1 
ATOM 6559 C CA  . PRO E 5 169 ? 293.934 327.215 443.390 1.00 94.30  ? 169 PRO C CA  1 
ATOM 6560 C C   . PRO E 5 169 ? 293.125 327.262 444.685 1.00 94.30  ? 169 PRO C C   1 
ATOM 6561 O O   . PRO E 5 169 ? 293.665 327.402 445.783 1.00 94.30  ? 169 PRO C O   1 
ATOM 6562 C CB  . PRO E 5 169 ? 294.373 325.780 443.065 1.00 94.30  ? 169 PRO C CB  1 
ATOM 6563 C CG  . PRO E 5 169 ? 295.822 325.729 443.369 1.00 94.30  ? 169 PRO C CG  1 
ATOM 6564 C CD  . PRO E 5 169 ? 296.354 327.092 443.130 1.00 94.30  ? 169 PRO C CD  1 
ATOM 6565 N N   . TRP E 5 170 ? 291.803 327.128 444.534 1.00 96.64  ? 170 TRP C N   1 
ATOM 6566 C CA  . TRP E 5 170 ? 290.854 327.151 445.643 1.00 96.64  ? 170 TRP C CA  1 
ATOM 6567 C C   . TRP E 5 170 ? 289.774 326.123 445.342 1.00 96.64  ? 170 TRP C C   1 
ATOM 6568 O O   . TRP E 5 170 ? 289.227 326.109 444.238 1.00 96.64  ? 170 TRP C O   1 
ATOM 6569 C CB  . TRP E 5 170 ? 290.246 328.553 445.828 1.00 96.64  ? 170 TRP C CB  1 
ATOM 6570 C CG  . TRP E 5 170 ? 289.718 328.878 447.225 1.00 96.64  ? 170 TRP C CG  1 
ATOM 6571 C CD1 . TRP E 5 170 ? 290.293 328.531 448.408 1.00 96.64  ? 170 TRP C CD1 1 
ATOM 6572 C CD2 . TRP E 5 170 ? 288.582 329.704 447.569 1.00 96.64  ? 170 TRP C CD2 1 
ATOM 6573 N NE1 . TRP E 5 170 ? 289.564 329.028 449.459 1.00 96.64  ? 170 TRP C NE1 1 
ATOM 6574 C CE2 . TRP E 5 170 ? 288.514 329.756 448.972 1.00 96.64  ? 170 TRP C CE2 1 
ATOM 6575 C CE3 . TRP E 5 170 ? 287.602 330.370 446.829 1.00 96.64  ? 170 TRP C CE3 1 
ATOM 6576 C CZ2 . TRP E 5 170 ? 287.518 330.452 449.646 1.00 96.64  ? 170 TRP C CZ2 1 
ATOM 6577 C CZ3 . TRP E 5 170 ? 286.619 331.068 447.505 1.00 96.64  ? 170 TRP C CZ3 1 
ATOM 6578 C CH2 . TRP E 5 170 ? 286.581 331.098 448.896 1.00 96.64  ? 170 TRP C CH2 1 
ATOM 6579 N N   . ILE E 5 171 ? 289.481 325.262 446.315 1.00 99.26  ? 171 ILE C N   1 
ATOM 6580 C CA  . ILE E 5 171 ? 288.585 324.128 446.141 1.00 99.26  ? 171 ILE C CA  1 
ATOM 6581 C C   . ILE E 5 171 ? 287.538 324.196 447.248 1.00 99.26  ? 171 ILE C C   1 
ATOM 6582 O O   . ILE E 5 171 ? 287.724 324.870 448.261 1.00 99.26  ? 171 ILE C O   1 
ATOM 6583 C CB  . ILE E 5 171 ? 289.374 322.794 446.179 1.00 99.26  ? 171 ILE C CB  1 
ATOM 6584 C CG1 . ILE E 5 171 ? 288.608 321.632 445.548 1.00 99.26  ? 171 ILE C CG1 1 
ATOM 6585 C CG2 . ILE E 5 171 ? 289.797 322.443 447.596 1.00 99.26  ? 171 ILE C CG2 1 
ATOM 6586 C CD1 . ILE E 5 171 ? 288.449 321.757 444.078 1.00 99.26  ? 171 ILE C CD1 1 
ATOM 6587 N N   . SER E 5 172 ? 286.414 323.518 447.040 1.00 94.56  ? 172 SER C N   1 
ATOM 6588 C CA  . SER E 5 172 ? 285.384 323.454 448.073 1.00 94.56  ? 172 SER C CA  1 
ATOM 6589 C C   . SER E 5 172 ? 285.697 322.397 449.120 1.00 94.56  ? 172 SER C C   1 
ATOM 6590 O O   . SER E 5 172 ? 284.855 322.081 449.958 1.00 94.56  ? 172 SER C O   1 
ATOM 6591 C CB  . SER E 5 172 ? 284.020 323.169 447.466 1.00 94.56  ? 172 SER C CB  1 
ATOM 6592 O OG  . SER E 5 172 ? 283.053 323.033 448.489 1.00 94.56  ? 172 SER C OG  1 
ATOM 6593 N N   . ALA E 5 186 ? 292.032 321.178 456.205 1.00 102.46 ? 186 ALA C N   1 
ATOM 6594 C CA  . ALA E 5 186 ? 292.956 322.232 455.812 1.00 102.46 ? 186 ALA C CA  1 
ATOM 6595 C C   . ALA E 5 186 ? 292.810 322.562 454.331 1.00 102.46 ? 186 ALA C C   1 
ATOM 6596 O O   . ALA E 5 186 ? 292.440 321.704 453.532 1.00 102.46 ? 186 ALA C O   1 
ATOM 6597 C CB  . ALA E 5 186 ? 294.379 321.824 456.126 1.00 102.46 ? 186 ALA C CB  1 
ATOM 6598 N N   . ALA E 5 187 ? 293.085 323.818 453.968 1.00 100.92 ? 187 ALA C N   1 
ATOM 6599 C CA  . ALA E 5 187 ? 293.016 324.224 452.573 1.00 100.92 ? 187 ALA C CA  1 
ATOM 6600 C C   . ALA E 5 187 ? 294.075 325.233 452.150 1.00 100.92 ? 187 ALA C C   1 
ATOM 6601 O O   . ALA E 5 187 ? 294.059 325.652 450.989 1.00 100.92 ? 187 ALA C O   1 
ATOM 6602 C CB  . ALA E 5 187 ? 291.630 324.795 452.254 1.00 100.92 ? 187 ALA C CB  1 
ATOM 6603 N N   . GLY E 5 188 ? 294.987 325.636 453.029 1.00 97.04  ? 188 GLY C N   1 
ATOM 6604 C CA  . GLY E 5 188 ? 296.056 326.523 452.611 1.00 97.04  ? 188 GLY C CA  1 
ATOM 6605 C C   . GLY E 5 188 ? 296.184 327.798 453.416 1.00 97.04  ? 188 GLY C C   1 
ATOM 6606 O O   . GLY E 5 188 ? 295.295 328.139 454.197 1.00 97.04  ? 188 GLY C O   1 
ATOM 6607 N N   . TYR E 5 189 ? 297.288 328.512 453.232 1.00 95.47  ? 189 TYR C N   1 
ATOM 6608 C CA  . TYR E 5 189 ? 297.557 329.747 453.950 1.00 95.47  ? 189 TYR C CA  1 
ATOM 6609 C C   . TYR E 5 189 ? 298.298 330.699 453.030 1.00 95.47  ? 189 TYR C C   1 
ATOM 6610 O O   . TYR E 5 189 ? 299.057 330.262 452.166 1.00 95.47  ? 189 TYR C O   1 
ATOM 6611 C CB  . TYR E 5 189 ? 298.392 329.492 455.194 1.00 95.47  ? 189 TYR C CB  1 
ATOM 6612 C CG  . TYR E 5 189 ? 297.585 329.129 456.400 1.00 95.47  ? 189 TYR C CG  1 
ATOM 6613 C CD1 . TYR E 5 189 ? 297.275 327.810 456.672 1.00 95.47  ? 189 TYR C CD1 1 
ATOM 6614 C CD2 . TYR E 5 189 ? 297.142 330.105 457.274 1.00 95.47  ? 189 TYR C CD2 1 
ATOM 6615 C CE1 . TYR E 5 189 ? 296.536 327.472 457.778 1.00 95.47  ? 189 TYR C CE1 1 
ATOM 6616 C CE2 . TYR E 5 189 ? 296.405 329.781 458.382 1.00 95.47  ? 189 TYR C CE2 1 
ATOM 6617 C CZ  . TYR E 5 189 ? 296.103 328.462 458.631 1.00 95.47  ? 189 TYR C CZ  1 
ATOM 6618 O OH  . TYR E 5 189 ? 295.363 328.128 459.741 1.00 95.47  ? 189 TYR C OH  1 
ATOM 6619 N N   . VAL E 5 190 ? 298.059 332.001 453.196 1.00 83.32  ? 190 VAL C N   1 
ATOM 6620 C CA  . VAL E 5 190 ? 298.675 333.009 452.340 1.00 83.32  ? 190 VAL C CA  1 
ATOM 6621 C C   . VAL E 5 190 ? 299.459 333.978 453.219 1.00 83.32  ? 190 VAL C C   1 
ATOM 6622 O O   . VAL E 5 190 ? 299.369 335.197 453.048 1.00 83.32  ? 190 VAL C O   1 
ATOM 6623 C CB  . VAL E 5 190 ? 297.644 333.750 451.467 1.00 83.32  ? 190 VAL C CB  1 
ATOM 6624 C CG1 . VAL E 5 190 ? 298.295 334.302 450.202 1.00 83.32  ? 190 VAL C CG1 1 
ATOM 6625 C CG2 . VAL E 5 190 ? 296.492 332.862 451.086 1.00 83.32  ? 190 VAL C CG2 1 
ATOM 6626 N N   . THR E 5 191 ? 300.142 333.453 454.234 1.00 84.71  ? 191 THR C N   1 
ATOM 6627 C CA  . THR E 5 191 ? 300.887 334.284 455.176 1.00 84.71  ? 191 THR C CA  1 
ATOM 6628 C C   . THR E 5 191 ? 301.995 335.077 454.493 1.00 84.71  ? 191 THR C C   1 
ATOM 6629 O O   . THR E 5 191 ? 302.545 334.669 453.471 1.00 84.71  ? 191 THR C O   1 
ATOM 6630 C CB  . THR E 5 191 ? 301.503 333.420 456.263 1.00 84.71  ? 191 THR C CB  1 
ATOM 6631 O OG1 . THR E 5 191 ? 302.674 332.789 455.743 1.00 84.71  ? 191 THR C OG1 1 
ATOM 6632 C CG2 . THR E 5 191 ? 300.537 332.353 456.689 1.00 84.71  ? 191 THR C CG2 1 
ATOM 6633 N N   . CYS E 5 192 ? 302.322 336.226 455.078 1.00 88.78  ? 192 CYS C N   1 
ATOM 6634 C CA  . CYS E 5 192 ? 303.296 337.165 454.540 1.00 88.78  ? 192 CYS C CA  1 
ATOM 6635 C C   . CYS E 5 192 ? 304.219 337.636 455.647 1.00 88.78  ? 192 CYS C C   1 
ATOM 6636 O O   . CYS E 5 192 ? 303.762 337.924 456.754 1.00 88.78  ? 192 CYS C O   1 
ATOM 6637 C CB  . CYS E 5 192 ? 302.599 338.359 453.910 1.00 88.78  ? 192 CYS C CB  1 
ATOM 6638 S SG  . CYS E 5 192 ? 303.646 339.779 453.598 1.00 88.78  ? 192 CYS C SG  1 
ATOM 6639 N N   . TRP E 5 193 ? 305.506 337.753 455.342 1.00 89.54  ? 193 TRP C N   1 
ATOM 6640 C CA  . TRP E 5 193 ? 306.514 337.970 456.366 1.00 89.54  ? 193 TRP C CA  1 
ATOM 6641 C C   . TRP E 5 193 ? 307.366 339.181 456.043 1.00 89.54  ? 193 TRP C C   1 
ATOM 6642 O O   . TRP E 5 193 ? 307.590 339.512 454.879 1.00 89.54  ? 193 TRP C O   1 
ATOM 6643 C CB  . TRP E 5 193 ? 307.422 336.765 456.506 1.00 89.54  ? 193 TRP C CB  1 
ATOM 6644 C CG  . TRP E 5 193 ? 306.708 335.539 456.871 1.00 89.54  ? 193 TRP C CG  1 
ATOM 6645 C CD1 . TRP E 5 193 ? 306.100 334.674 456.031 1.00 89.54  ? 193 TRP C CD1 1 
ATOM 6646 C CD2 . TRP E 5 193 ? 306.525 335.026 458.182 1.00 89.54  ? 193 TRP C CD2 1 
ATOM 6647 N NE1 . TRP E 5 193 ? 305.538 333.649 456.735 1.00 89.54  ? 193 TRP C NE1 1 
ATOM 6648 C CE2 . TRP E 5 193 ? 305.789 333.843 458.064 1.00 89.54  ? 193 TRP C CE2 1 
ATOM 6649 C CE3 . TRP E 5 193 ? 306.911 335.454 459.448 1.00 89.54  ? 193 TRP C CE3 1 
ATOM 6650 C CZ2 . TRP E 5 193 ? 305.430 333.084 459.158 1.00 89.54  ? 193 TRP C CZ2 1 
ATOM 6651 C CZ3 . TRP E 5 193 ? 306.557 334.698 460.532 1.00 89.54  ? 193 TRP C CZ3 1 
ATOM 6652 C CH2 . TRP E 5 193 ? 305.825 333.526 460.383 1.00 89.54  ? 193 TRP C CH2 1 
ATOM 6653 N N   . TYR E 5 194 ? 307.850 339.829 457.094 1.00 91.22  ? 194 TYR C N   1 
ATOM 6654 C CA  . TYR E 5 194 ? 308.829 340.891 456.940 1.00 91.22  ? 194 TYR C CA  1 
ATOM 6655 C C   . TYR E 5 194 ? 310.159 340.297 456.522 1.00 91.22  ? 194 TYR C C   1 
ATOM 6656 O O   . TYR E 5 194 ? 310.676 339.394 457.180 1.00 91.22  ? 194 TYR C O   1 
ATOM 6657 C CB  . TYR E 5 194 ? 309.014 341.644 458.248 1.00 91.22  ? 194 TYR C CB  1 
ATOM 6658 C CG  . TYR E 5 194 ? 308.120 342.829 458.440 1.00 91.22  ? 194 TYR C CG  1 
ATOM 6659 C CD1 . TYR E 5 194 ? 308.102 343.862 457.526 1.00 91.22  ? 194 TYR C CD1 1 
ATOM 6660 C CD2 . TYR E 5 194 ? 307.316 342.926 459.557 1.00 91.22  ? 194 TYR C CD2 1 
ATOM 6661 C CE1 . TYR E 5 194 ? 307.292 344.945 457.712 1.00 91.22  ? 194 TYR C CE1 1 
ATOM 6662 C CE2 . TYR E 5 194 ? 306.503 344.002 459.751 1.00 91.22  ? 194 TYR C CE2 1 
ATOM 6663 C CZ  . TYR E 5 194 ? 306.494 345.008 458.828 1.00 91.22  ? 194 TYR C CZ  1 
ATOM 6664 O OH  . TYR E 5 194 ? 305.676 346.088 459.034 1.00 91.22  ? 194 TYR C OH  1 
ATOM 6665 N N   . GLN E 5 195 ? 310.728 340.808 455.438 1.00 86.27  ? 195 GLN C N   1 
ATOM 6666 C CA  . GLN E 5 195 ? 312.088 340.447 455.076 1.00 86.27  ? 195 GLN C CA  1 
ATOM 6667 C C   . GLN E 5 195 ? 313.082 341.429 455.681 1.00 86.27  ? 195 GLN C C   1 
ATOM 6668 O O   . GLN E 5 195 ? 313.946 341.039 456.467 1.00 86.27  ? 195 GLN C O   1 
ATOM 6669 C CB  . GLN E 5 195 ? 312.237 340.392 453.557 1.00 86.27  ? 195 GLN C CB  1 
ATOM 6670 C CG  . GLN E 5 195 ? 313.650 340.179 453.101 1.00 86.27  ? 195 GLN C CG  1 
ATOM 6671 C CD  . GLN E 5 195 ? 314.054 338.740 453.156 1.00 86.27  ? 195 GLN C CD  1 
ATOM 6672 O OE1 . GLN E 5 195 ? 313.212 337.854 453.198 1.00 86.27  ? 195 GLN C OE1 1 
ATOM 6673 N NE2 . GLN E 5 195 ? 315.350 338.492 453.154 1.00 86.27  ? 195 GLN C NE2 1 
ATOM 6674 N N   . THR E 5 196 ? 312.972 342.703 455.323 1.00 89.76  ? 196 THR C N   1 
ATOM 6675 C CA  . THR E 5 196 ? 313.716 343.783 455.951 1.00 89.76  ? 196 THR C CA  1 
ATOM 6676 C C   . THR E 5 196 ? 312.726 344.833 456.423 1.00 89.76  ? 196 THR C C   1 
ATOM 6677 O O   . THR E 5 196 ? 311.531 344.759 456.137 1.00 89.76  ? 196 THR C O   1 
ATOM 6678 C CB  . THR E 5 196 ? 314.715 344.427 454.993 1.00 89.76  ? 196 THR C CB  1 
ATOM 6679 O OG1 . THR E 5 196 ? 313.996 345.100 453.958 1.00 89.76  ? 196 THR C OG1 1 
ATOM 6680 C CG2 . THR E 5 196 ? 315.627 343.395 454.375 1.00 89.76  ? 196 THR C CG2 1 
ATOM 6681 N N   . ASN E 5 197 ? 313.227 345.835 457.132 1.00 93.66  ? 197 ASN C N   1 
ATOM 6682 C CA  . ASN E 5 197 ? 312.355 346.900 457.597 1.00 93.66  ? 197 ASN C CA  1 
ATOM 6683 C C   . ASN E 5 197 ? 312.034 347.869 456.467 1.00 93.66  ? 197 ASN C C   1 
ATOM 6684 O O   . ASN E 5 197 ? 312.493 347.725 455.333 1.00 93.66  ? 197 ASN C O   1 
ATOM 6685 C CB  . ASN E 5 197 ? 312.997 347.651 458.751 1.00 93.66  ? 197 ASN C CB  1 
ATOM 6686 C CG  . ASN E 5 197 ? 313.399 346.742 459.865 1.00 93.66  ? 197 ASN C CG  1 
ATOM 6687 O OD1 . ASN E 5 197 ? 312.808 345.683 460.051 1.00 93.66  ? 197 ASN C OD1 1 
ATOM 6688 N ND2 . ASN E 5 197 ? 314.415 347.140 460.618 1.00 93.66  ? 197 ASN C ND2 1 
ATOM 6689 N N   . ILE E 5 198 ? 311.232 348.874 456.793 1.00 92.83  ? 198 ILE C N   1 
ATOM 6690 C CA  . ILE E 5 198 ? 310.890 349.934 455.854 1.00 92.83  ? 198 ILE C CA  1 
ATOM 6691 C C   . ILE E 5 198 ? 311.900 351.056 456.045 1.00 92.83  ? 198 ILE C C   1 
ATOM 6692 O O   . ILE E 5 198 ? 311.826 351.807 457.019 1.00 92.83  ? 198 ILE C O   1 
ATOM 6693 C CB  . ILE E 5 198 ? 309.459 350.433 456.068 1.00 92.83  ? 198 ILE C CB  1 
ATOM 6694 C CG1 . ILE E 5 198 ? 308.471 349.276 455.978 1.00 92.83  ? 198 ILE C CG1 1 
ATOM 6695 C CG2 . ILE E 5 198 ? 309.114 351.479 455.045 1.00 92.83  ? 198 ILE C CG2 1 
ATOM 6696 C CD1 . ILE E 5 198 ? 308.400 348.648 454.621 1.00 92.83  ? 198 ILE C CD1 1 
ATOM 6697 N N   . VAL E 5 199 ? 312.851 351.165 455.132 1.00 89.47  ? 199 VAL C N   1 
ATOM 6698 C CA  . VAL E 5 199 ? 313.837 352.235 455.188 1.00 89.47  ? 199 VAL C CA  1 
ATOM 6699 C C   . VAL E 5 199 ? 313.242 353.486 454.566 1.00 89.47  ? 199 VAL C C   1 
ATOM 6700 O O   . VAL E 5 199 ? 312.711 353.449 453.453 1.00 89.47  ? 199 VAL C O   1 
ATOM 6701 C CB  . VAL E 5 199 ? 315.125 351.812 454.472 1.00 89.47  ? 199 VAL C CB  1 
ATOM 6702 C CG1 . VAL E 5 199 ? 316.121 352.936 454.487 1.00 89.47  ? 199 VAL C CG1 1 
ATOM 6703 C CG2 . VAL E 5 199 ? 315.703 350.594 455.139 1.00 89.47  ? 199 VAL C CG2 1 
ATOM 6704 N N   . VAL E 5 200 ? 313.326 354.603 455.280 1.00 90.26  ? 200 VAL C N   1 
ATOM 6705 C CA  . VAL E 5 200 ? 312.614 355.807 454.867 1.00 90.26  ? 200 VAL C CA  1 
ATOM 6706 C C   . VAL E 5 200 ? 313.500 357.026 455.124 1.00 90.26  ? 200 VAL C C   1 
ATOM 6707 O O   . VAL E 5 200 ? 314.264 357.039 456.098 1.00 90.26  ? 200 VAL C O   1 
ATOM 6708 C CB  . VAL E 5 200 ? 311.247 355.867 455.576 1.00 90.26  ? 200 VAL C CB  1 
ATOM 6709 C CG1 . VAL E 5 200 ? 311.371 356.128 457.072 1.00 90.26  ? 200 VAL C CG1 1 
ATOM 6710 C CG2 . VAL E 5 200 ? 310.324 356.844 454.921 1.00 90.26  ? 200 VAL C CG2 1 
ATOM 6711 N N   . PRO E 5 201 ? 313.501 358.034 454.249 1.00 89.31  ? 201 PRO C N   1 
ATOM 6712 C CA  . PRO E 5 201 ? 314.328 359.221 454.499 1.00 89.31  ? 201 PRO C CA  1 
ATOM 6713 C C   . PRO E 5 201 ? 313.743 360.156 455.537 1.00 89.31  ? 201 PRO C C   1 
ATOM 6714 O O   . PRO E 5 201 ? 312.745 359.835 456.183 1.00 89.31  ? 201 PRO C O   1 
ATOM 6715 C CB  . PRO E 5 201 ? 314.383 359.903 453.131 1.00 89.31  ? 201 PRO C CB  1 
ATOM 6716 C CG  . PRO E 5 201 ? 314.071 358.852 452.176 1.00 89.31  ? 201 PRO C CG  1 
ATOM 6717 C CD  . PRO E 5 201 ? 313.091 357.967 452.841 1.00 89.31  ? 201 PRO C CD  1 
ATOM 6718 N N   . ALA E 5 202 ? 314.363 361.317 455.705 1.00 94.56  ? 202 ALA C N   1 
ATOM 6719 C CA  . ALA E 5 202 ? 313.876 362.297 456.660 1.00 94.56  ? 202 ALA C CA  1 
ATOM 6720 C C   . ALA E 5 202 ? 312.632 362.992 456.131 1.00 94.56  ? 202 ALA C C   1 
ATOM 6721 O O   . ALA E 5 202 ? 312.439 363.118 454.919 1.00 94.56  ? 202 ALA C O   1 
ATOM 6722 C CB  . ALA E 5 202 ? 314.951 363.336 456.960 1.00 94.56  ? 202 ALA C CB  1 
ATOM 6723 N N   . ASP E 5 203 ? 311.784 363.427 457.070 1.00 99.56  ? 203 ASP C N   1 
ATOM 6724 C CA  . ASP E 5 203 ? 310.542 364.167 456.808 1.00 99.56  ? 203 ASP C CA  1 
ATOM 6725 C C   . ASP E 5 203 ? 309.568 363.379 455.934 1.00 99.56  ? 203 ASP C C   1 
ATOM 6726 O O   . ASP E 5 203 ? 308.838 363.948 455.124 1.00 99.56  ? 203 ASP C O   1 
ATOM 6727 C CB  . ASP E 5 203 ? 310.822 365.546 456.206 1.00 99.56  ? 203 ASP C CB  1 
ATOM 6728 C CG  . ASP E 5 203 ? 311.232 366.562 457.251 1.00 99.56  ? 203 ASP C CG  1 
ATOM 6729 O OD1 . ASP E 5 203 ? 310.617 366.573 458.337 1.00 99.56  ? 203 ASP C OD1 1 
ATOM 6730 O OD2 . ASP E 5 203 ? 312.167 367.350 456.995 1.00 99.56  ? 203 ASP C OD2 1 
ATOM 6731 N N   . VAL E 5 204 ? 309.559 362.056 456.092 1.00 92.12  ? 204 VAL C N   1 
ATOM 6732 C CA  . VAL E 5 204 ? 308.558 361.182 455.490 1.00 92.12  ? 204 VAL C CA  1 
ATOM 6733 C C   . VAL E 5 204 ? 307.981 360.313 456.595 1.00 92.12  ? 204 VAL C C   1 
ATOM 6734 O O   . VAL E 5 204 ? 308.713 359.874 457.488 1.00 92.12  ? 204 VAL C O   1 
ATOM 6735 C CB  . VAL E 5 204 ? 309.140 360.286 454.376 1.00 92.12  ? 204 VAL C CB  1 
ATOM 6736 C CG1 . VAL E 5 204 ? 308.038 359.693 453.534 1.00 92.12  ? 204 VAL C CG1 1 
ATOM 6737 C CG2 . VAL E 5 204 ? 310.121 361.021 453.503 1.00 92.12  ? 204 VAL C CG2 1 
ATOM 6738 N N   . GLN E 5 205 ? 306.675 360.073 456.548 1.00 95.43  ? 205 GLN C N   1 
ATOM 6739 C CA  . GLN E 5 205 ? 306.056 359.149 457.487 1.00 95.43  ? 205 GLN C CA  1 
ATOM 6740 C C   . GLN E 5 205 ? 306.464 357.719 457.170 1.00 95.43  ? 205 GLN C C   1 
ATOM 6741 O O   . GLN E 5 205 ? 306.787 357.382 456.030 1.00 95.43  ? 205 GLN C O   1 
ATOM 6742 C CB  . GLN E 5 205 ? 304.541 359.271 457.436 1.00 95.43  ? 205 GLN C CB  1 
ATOM 6743 C CG  . GLN E 5 205 ? 303.999 360.368 458.308 1.00 95.43  ? 205 GLN C CG  1 
ATOM 6744 C CD  . GLN E 5 205 ? 304.313 360.145 459.761 1.00 95.43  ? 205 GLN C CD  1 
ATOM 6745 O OE1 . GLN E 5 205 ? 304.100 359.058 460.289 1.00 95.43  ? 205 GLN C OE1 1 
ATOM 6746 N NE2 . GLN E 5 205 ? 304.832 361.170 460.418 1.00 95.43  ? 205 GLN C NE2 1 
ATOM 6747 N N   . SER E 5 206 ? 306.444 356.868 458.193 1.00 98.19  ? 206 SER C N   1 
ATOM 6748 C CA  . SER E 5 206 ? 306.888 355.491 458.040 1.00 98.19  ? 206 SER C CA  1 
ATOM 6749 C C   . SER E 5 206 ? 305.752 354.480 458.000 1.00 98.19  ? 206 SER C C   1 
ATOM 6750 O O   . SER E 5 206 ? 305.925 353.407 457.418 1.00 98.19  ? 206 SER C O   1 
ATOM 6751 C CB  . SER E 5 206 ? 307.841 355.114 459.175 1.00 98.19  ? 206 SER C CB  1 
ATOM 6752 O OG  . SER E 5 206 ? 307.328 355.554 460.416 1.00 98.19  ? 206 SER C OG  1 
ATOM 6753 N N   . SER E 5 207 ? 304.605 354.786 458.596 1.00 98.10  ? 207 SER C N   1 
ATOM 6754 C CA  . SER E 5 207 ? 303.494 353.841 458.680 1.00 98.10  ? 207 SER C CA  1 
ATOM 6755 C C   . SER E 5 207 ? 302.781 353.780 457.337 1.00 98.10  ? 207 SER C C   1 
ATOM 6756 O O   . SER E 5 207 ? 301.911 354.601 457.047 1.00 98.10  ? 207 SER C O   1 
ATOM 6757 C CB  . SER E 5 207 ? 302.533 354.254 459.785 1.00 98.10  ? 207 SER C CB  1 
ATOM 6758 O OG  . SER E 5 207 ? 303.177 354.251 461.043 1.00 98.10  ? 207 SER C OG  1 
ATOM 6759 N N   . CYS E 5 208 ? 303.128 352.800 456.516 1.00 94.82  ? 208 CYS C N   1 
ATOM 6760 C CA  . CYS E 5 208 ? 302.475 352.605 455.233 1.00 94.82  ? 208 CYS C CA  1 
ATOM 6761 C C   . CYS E 5 208 ? 301.483 351.452 455.317 1.00 94.82  ? 208 CYS C C   1 
ATOM 6762 O O   . CYS E 5 208 ? 301.536 350.622 456.221 1.00 94.82  ? 208 CYS C O   1 
ATOM 6763 C CB  . CYS E 5 208 ? 303.513 352.346 454.145 1.00 94.82  ? 208 CYS C CB  1 
ATOM 6764 S SG  . CYS E 5 208 ? 304.983 353.370 454.293 1.00 94.82  ? 208 CYS C SG  1 
ATOM 6765 N N   . ASP E 5 209 ? 300.538 351.428 454.381 1.00 91.68  ? 209 ASP C N   1 
ATOM 6766 C CA  . ASP E 5 209 ? 299.466 350.442 454.394 1.00 91.68  ? 209 ASP C CA  1 
ATOM 6767 C C   . ASP E 5 209 ? 299.497 349.643 453.100 1.00 91.68  ? 209 ASP C C   1 
ATOM 6768 O O   . ASP E 5 209 ? 300.109 350.048 452.114 1.00 91.68  ? 209 ASP C O   1 
ATOM 6769 C CB  . ASP E 5 209 ? 298.094 351.101 454.574 1.00 91.68  ? 209 ASP C CB  1 
ATOM 6770 C CG  . ASP E 5 209 ? 297.891 351.694 455.965 1.00 91.68  ? 209 ASP C CG  1 
ATOM 6771 O OD1 . ASP E 5 209 ? 298.861 352.123 456.613 1.00 91.68  ? 209 ASP C OD1 1 
ATOM 6772 O OD2 . ASP E 5 209 ? 296.731 351.750 456.418 1.00 91.68  ? 209 ASP C OD2 1 
ATOM 6773 N N   . ILE E 5 210 ? 298.820 348.495 453.104 1.00 82.34  ? 210 ILE C N   1 
ATOM 6774 C CA  . ILE E 5 210 ? 298.816 347.567 451.976 1.00 82.34  ? 210 ILE C CA  1 
ATOM 6775 C C   . ILE E 5 210 ? 297.384 347.123 451.717 1.00 82.34  ? 210 ILE C C   1 
ATOM 6776 O O   . ILE E 5 210 ? 296.693 346.695 452.644 1.00 82.34  ? 210 ILE C O   1 
ATOM 6777 C CB  . ILE E 5 210 ? 299.712 346.344 452.251 1.00 82.34  ? 210 ILE C CB  1 
ATOM 6778 C CG1 . ILE E 5 210 ? 301.183 346.722 452.191 1.00 82.34  ? 210 ILE C CG1 1 
ATOM 6779 C CG2 . ILE E 5 210 ? 299.452 345.232 451.264 1.00 82.34  ? 210 ILE C CG2 1 
ATOM 6780 C CD1 . ILE E 5 210 ? 302.104 345.570 452.468 1.00 82.34  ? 210 ILE C CD1 1 
ATOM 6781 N N   . LEU E 5 211 ? 296.931 347.228 450.471 1.00 79.69  ? 211 LEU C N   1 
ATOM 6782 C CA  . LEU E 5 211 ? 295.636 346.703 450.064 1.00 79.69  ? 211 LEU C CA  1 
ATOM 6783 C C   . LEU E 5 211 ? 295.801 345.342 449.400 1.00 79.69  ? 211 LEU C C   1 
ATOM 6784 O O   . LEU E 5 211 ? 296.872 345.001 448.899 1.00 79.69  ? 211 LEU C O   1 
ATOM 6785 C CB  . LEU E 5 211 ? 294.941 347.657 449.100 1.00 79.69  ? 211 LEU C CB  1 
ATOM 6786 C CG  . LEU E 5 211 ? 294.639 349.038 449.648 1.00 79.69  ? 211 LEU C CG  1 
ATOM 6787 C CD1 . LEU E 5 211 ? 293.958 349.847 448.593 1.00 79.69  ? 211 LEU C CD1 1 
ATOM 6788 C CD2 . LEU E 5 211 ? 293.754 348.903 450.841 1.00 79.69  ? 211 LEU C CD2 1 
ATOM 6789 N N   . CYS E 5 212 ? 294.715 344.571 449.385 1.00 80.69  ? 212 CYS C N   1 
ATOM 6790 C CA  . CYS E 5 212 ? 294.728 343.223 448.834 1.00 80.69  ? 212 CYS C CA  1 
ATOM 6791 C C   . CYS E 5 212 ? 293.481 342.995 447.998 1.00 80.69  ? 212 CYS C C   1 
ATOM 6792 O O   . CYS E 5 212 ? 292.383 343.368 448.412 1.00 80.69  ? 212 CYS C O   1 
ATOM 6793 C CB  . CYS E 5 212 ? 294.804 342.179 449.945 1.00 80.69  ? 212 CYS C CB  1 
ATOM 6794 S SG  . CYS E 5 212 ? 294.518 340.499 449.387 1.00 80.69  ? 212 CYS C SG  1 
ATOM 6795 N N   . PHE E 5 213 ? 293.647 342.362 446.843 1.00 77.62  ? 213 PHE C N   1 
ATOM 6796 C CA  . PHE E 5 213 ? 292.580 342.191 445.867 1.00 77.62  ? 213 PHE C CA  1 
ATOM 6797 C C   . PHE E 5 213 ? 292.364 340.708 445.622 1.00 77.62  ? 213 PHE C C   1 
ATOM 6798 O O   . PHE E 5 213 ? 293.219 339.888 445.950 1.00 77.62  ? 213 PHE C O   1 
ATOM 6799 C CB  . PHE E 5 213 ? 292.917 342.871 444.540 1.00 77.62  ? 213 PHE C CB  1 
ATOM 6800 C CG  . PHE E 5 213 ? 292.877 344.374 444.579 1.00 77.62  ? 213 PHE C CG  1 
ATOM 6801 C CD1 . PHE E 5 213 ? 293.846 345.097 445.243 1.00 77.62  ? 213 PHE C CD1 1 
ATOM 6802 C CD2 . PHE E 5 213 ? 291.899 345.061 443.900 1.00 77.62  ? 213 PHE C CD2 1 
ATOM 6803 C CE1 . PHE E 5 213 ? 293.816 346.460 445.264 1.00 77.62  ? 213 PHE C CE1 1 
ATOM 6804 C CE2 . PHE E 5 213 ? 291.872 346.431 443.918 1.00 77.62  ? 213 PHE C CE2 1 
ATOM 6805 C CZ  . PHE E 5 213 ? 292.833 347.124 444.603 1.00 77.62  ? 213 PHE C CZ  1 
ATOM 6806 N N   . VAL E 5 214 ? 291.224 340.355 445.035 1.00 81.46  ? 214 VAL C N   1 
ATOM 6807 C CA  . VAL E 5 214 ? 290.922 338.957 444.756 1.00 81.46  ? 214 VAL C CA  1 
ATOM 6808 C C   . VAL E 5 214 ? 290.046 338.903 443.511 1.00 81.46  ? 214 VAL C C   1 
ATOM 6809 O O   . VAL E 5 214 ? 289.340 339.861 443.187 1.00 81.46  ? 214 VAL C O   1 
ATOM 6810 C CB  . VAL E 5 214 ? 290.262 338.273 445.974 1.00 81.46  ? 214 VAL C CB  1 
ATOM 6811 C CG1 . VAL E 5 214 ? 288.819 338.686 446.133 1.00 81.46  ? 214 VAL C CG1 1 
ATOM 6812 C CG2 . VAL E 5 214 ? 290.407 336.769 445.925 1.00 81.46  ? 214 VAL C CG2 1 
ATOM 6813 N N   . SER E 5 215 ? 290.114 337.788 442.790 1.00 88.74  ? 215 SER C N   1 
ATOM 6814 C CA  . SER E 5 215 ? 289.424 337.665 441.514 1.00 88.74  ? 215 SER C CA  1 
ATOM 6815 C C   . SER E 5 215 ? 289.210 336.183 441.219 1.00 88.74  ? 215 SER C C   1 
ATOM 6816 O O   . SER E 5 215 ? 289.288 335.346 442.124 1.00 88.74  ? 215 SER C O   1 
ATOM 6817 C CB  . SER E 5 215 ? 290.224 338.374 440.412 1.00 88.74  ? 215 SER C CB  1 
ATOM 6818 O OG  . SER E 5 215 ? 289.872 337.875 439.142 1.00 88.74  ? 215 SER C OG  1 
ATOM 6819 N N   . ALA E 5 216 ? 288.846 335.871 440.017 1.00 90.79  ? 216 ALA C N   1 
ATOM 6820 C CA  . ALA E 5 216 ? 288.624 334.507 439.657 1.00 90.79  ? 216 ALA C CA  1 
ATOM 6821 C C   . ALA E 5 216 ? 289.556 334.279 438.541 1.00 90.79  ? 216 ALA C C   1 
ATOM 6822 O O   . ALA E 5 216 ? 289.608 335.064 437.654 1.00 90.79  ? 216 ALA C O   1 
ATOM 6823 C CB  . ALA E 5 216 ? 287.242 334.350 439.183 1.00 90.79  ? 216 ALA C CB  1 
ATOM 6824 N N   . CYS E 5 217 ? 290.185 333.132 438.424 1.00 96.94  ? 217 CYS C N   1 
ATOM 6825 C CA  . CYS E 5 217 ? 291.222 333.013 437.407 1.00 96.94  ? 217 CYS C CA  1 
ATOM 6826 C C   . CYS E 5 217 ? 290.795 332.626 436.048 1.00 96.94  ? 217 CYS C C   1 
ATOM 6827 O O   . CYS E 5 217 ? 291.618 332.263 435.286 1.00 96.94  ? 217 CYS C O   1 
ATOM 6828 C CB  . CYS E 5 217 ? 292.471 332.236 437.868 1.00 96.94  ? 217 CYS C CB  1 
ATOM 6829 S SG  . CYS E 5 217 ? 294.114 332.744 437.214 1.00 96.94  ? 217 CYS C SG  1 
ATOM 6830 N N   . ASN E 5 218 ? 289.505 332.591 435.813 1.00 109.18 ? 218 ASN C N   1 
ATOM 6831 C CA  . ASN E 5 218 ? 288.814 332.354 434.543 1.00 109.18 ? 218 ASN C CA  1 
ATOM 6832 C C   . ASN E 5 218 ? 288.597 330.988 434.032 1.00 109.18 ? 218 ASN C C   1 
ATOM 6833 O O   . ASN E 5 218 ? 288.043 330.826 432.965 1.00 109.18 ? 218 ASN C O   1 
ATOM 6834 C CB  . ASN E 5 218 ? 289.248 333.242 433.402 1.00 109.18 ? 218 ASN C CB  1 
ATOM 6835 C CG  . ASN E 5 218 ? 288.790 334.634 433.593 1.00 109.18 ? 218 ASN C CG  1 
ATOM 6836 O OD1 . ASN E 5 218 ? 287.846 334.874 434.300 1.00 109.18 ? 218 ASN C OD1 1 
ATOM 6837 N ND2 . ASN E 5 218 ? 289.410 335.551 432.920 1.00 109.18 ? 218 ASN C ND2 1 
ATOM 6838 N N   . ASP E 5 219 ? 288.968 329.991 434.795 1.00 112.84 ? 219 ASP C N   1 
ATOM 6839 C CA  . ASP E 5 219 ? 288.679 328.679 434.328 1.00 112.84 ? 219 ASP C CA  1 
ATOM 6840 C C   . ASP E 5 219 ? 287.908 327.957 435.358 1.00 112.84 ? 219 ASP C C   1 
ATOM 6841 O O   . ASP E 5 219 ? 288.152 326.797 435.526 1.00 112.84 ? 219 ASP C O   1 
ATOM 6842 C CB  . ASP E 5 219 ? 289.936 327.964 433.955 1.00 112.84 ? 219 ASP C CB  1 
ATOM 6843 C CG  . ASP E 5 219 ? 290.886 327.905 435.069 1.00 112.84 ? 219 ASP C CG  1 
ATOM 6844 O OD1 . ASP E 5 219 ? 292.090 328.065 434.831 1.00 112.84 ? 219 ASP C OD1 1 
ATOM 6845 O OD2 . ASP E 5 219 ? 290.452 327.706 436.198 1.00 112.84 ? 219 ASP C OD2 1 
ATOM 6846 N N   . PHE E 5 220 ? 287.032 328.615 436.095 1.00 101.74 ? 220 PHE C N   1 
ATOM 6847 C CA  . PHE E 5 220 ? 286.350 327.851 437.085 1.00 101.74 ? 220 PHE C CA  1 
ATOM 6848 C C   . PHE E 5 220 ? 284.905 327.746 437.099 1.00 101.74 ? 220 PHE C C   1 
ATOM 6849 O O   . PHE E 5 220 ? 284.268 328.699 436.883 1.00 101.74 ? 220 PHE C O   1 
ATOM 6850 C CB  . PHE E 5 220 ? 287.011 328.009 438.405 1.00 101.74 ? 220 PHE C CB  1 
ATOM 6851 C CG  . PHE E 5 220 ? 287.087 329.367 438.914 1.00 101.74 ? 220 PHE C CG  1 
ATOM 6852 C CD1 . PHE E 5 220 ? 286.035 329.833 439.655 1.00 101.74 ? 220 PHE C CD1 1 
ATOM 6853 C CD2 . PHE E 5 220 ? 288.141 330.120 438.719 1.00 101.74 ? 220 PHE C CD2 1 
ATOM 6854 C CE1 . PHE E 5 220 ? 286.019 331.058 440.169 1.00 101.74 ? 220 PHE C CE1 1 
ATOM 6855 C CE2 . PHE E 5 220 ? 288.134 331.362 439.224 1.00 101.74 ? 220 PHE C CE2 1 
ATOM 6856 C CZ  . PHE E 5 220 ? 287.069 331.829 439.943 1.00 101.74 ? 220 PHE C CZ  1 
ATOM 6857 N N   . SER E 5 221 ? 284.427 326.543 437.358 1.00 101.46 ? 221 SER C N   1 
ATOM 6858 C CA  . SER E 5 221 ? 283.043 326.158 437.277 1.00 101.46 ? 221 SER C CA  1 
ATOM 6859 C C   . SER E 5 221 ? 282.282 325.942 438.508 1.00 101.46 ? 221 SER C C   1 
ATOM 6860 O O   . SER E 5 221 ? 282.833 325.489 439.436 1.00 101.46 ? 221 SER C O   1 
ATOM 6861 C CB  . SER E 5 221 ? 283.037 324.792 436.709 1.00 101.46 ? 221 SER C CB  1 
ATOM 6862 O OG  . SER E 5 221 ? 283.707 323.952 437.612 1.00 101.46 ? 221 SER C OG  1 
ATOM 6863 N N   . VAL E 5 222 ? 280.976 326.090 438.432 1.00 96.93  ? 222 VAL C N   1 
ATOM 6864 C CA  . VAL E 5 222 ? 280.067 325.910 439.528 1.00 96.93  ? 222 VAL C CA  1 
ATOM 6865 C C   . VAL E 5 222 ? 278.971 324.947 439.140 1.00 96.93  ? 222 VAL C C   1 
ATOM 6866 O O   . VAL E 5 222 ? 278.773 324.710 438.010 1.00 96.93  ? 222 VAL C O   1 
ATOM 6867 C CB  . VAL E 5 222 ? 279.365 327.174 439.730 1.00 96.93  ? 222 VAL C CB  1 
ATOM 6868 C CG1 . VAL E 5 222 ? 280.347 328.229 440.065 1.00 96.93  ? 222 VAL C CG1 1 
ATOM 6869 C CG2 . VAL E 5 222 ? 278.776 327.522 438.422 1.00 96.93  ? 222 VAL C CG2 1 
ATOM 6870 N N   . ARG E 5 223 ? 278.256 324.390 440.094 1.00 99.99  ? 223 ARG C N   1 
ATOM 6871 C CA  . ARG E 5 223 ? 277.192 323.419 439.898 1.00 99.99  ? 223 ARG C CA  1 
ATOM 6872 C C   . ARG E 5 223 ? 276.286 323.413 441.121 1.00 99.99  ? 223 ARG C C   1 
ATOM 6873 O O   . ARG E 5 223 ? 276.708 323.804 442.210 1.00 99.99  ? 223 ARG C O   1 
ATOM 6874 C CB  . ARG E 5 223 ? 277.761 322.022 439.652 1.00 99.99  ? 223 ARG C CB  1 
ATOM 6875 C CG  . ARG E 5 223 ? 276.913 321.170 438.739 1.00 99.99  ? 223 ARG C CG  1 
ATOM 6876 C CD  . ARG E 5 223 ? 277.754 320.230 437.894 1.00 99.99  ? 223 ARG C CD  1 
ATOM 6877 N NE  . ARG E 5 223 ? 278.351 319.158 438.678 1.00 99.99  ? 223 ARG C NE  1 
ATOM 6878 C CZ  . ARG E 5 223 ? 279.656 319.002 438.835 1.00 99.99  ? 223 ARG C CZ  1 
ATOM 6879 N NH1 . ARG E 5 223 ? 280.495 319.848 438.259 1.00 99.99  ? 223 ARG C NH1 1 
ATOM 6880 N NH2 . ARG E 5 223 ? 280.126 318.002 439.562 1.00 99.99  ? 223 ARG C NH2 1 
ATOM 6881 N N   . MET E 5 224 ? 275.040 322.961 440.919 1.00 101.50 ? 224 MET C N   1 
ATOM 6882 C CA  . MET E 5 224 ? 274.069 322.672 441.983 1.00 101.50 ? 224 MET C CA  1 
ATOM 6883 C C   . MET E 5 224 ? 273.739 323.920 442.809 1.00 101.50 ? 224 MET C C   1 
ATOM 6884 O O   . MET E 5 224 ? 274.231 324.110 443.919 1.00 101.50 ? 224 MET C O   1 
ATOM 6885 C CB  . MET E 5 224 ? 274.552 321.532 442.886 1.00 101.50 ? 224 MET C CB  1 
ATOM 6886 C CG  . MET E 5 224 ? 273.477 320.933 443.776 1.00 101.50 ? 224 MET C CG  1 
ATOM 6887 S SD  . MET E 5 224 ? 272.333 319.920 442.844 1.00 101.50 ? 224 MET C SD  1 
ATOM 6888 C CE  . MET E 5 224 ? 273.480 318.756 442.117 1.00 101.50 ? 224 MET C CE  1 
ATOM 6889 N N   . LEU E 5 225 ? 272.965 324.807 442.184 1.00 92.92  ? 225 LEU C N   1 
ATOM 6890 C CA  . LEU E 5 225 ? 272.520 326.036 442.833 1.00 92.92  ? 225 LEU C CA  1 
ATOM 6891 C C   . LEU E 5 225 ? 271.715 325.758 444.098 1.00 92.92  ? 225 LEU C C   1 
ATOM 6892 O O   . LEU E 5 225 ? 270.939 324.805 444.166 1.00 92.92  ? 225 LEU C O   1 
ATOM 6893 C CB  . LEU E 5 225 ? 271.688 326.865 441.854 1.00 92.92  ? 225 LEU C CB  1 
ATOM 6894 C CG  . LEU E 5 225 ? 271.299 328.302 442.215 1.00 92.92  ? 225 LEU C CG  1 
ATOM 6895 C CD1 . LEU E 5 225 ? 271.337 329.138 440.975 1.00 92.92  ? 225 LEU C CD1 1 
ATOM 6896 C CD2 . LEU E 5 225 ? 269.915 328.394 442.805 1.00 92.92  ? 225 LEU C CD2 1 
ATOM 6897 N N   . LYS E 5 226 ? 271.922 326.601 445.108 1.00 93.76  ? 226 LYS C N   1 
ATOM 6898 C CA  . LYS E 5 226 ? 271.141 326.593 446.336 1.00 93.76  ? 226 LYS C CA  1 
ATOM 6899 C C   . LYS E 5 226 ? 270.876 328.038 446.728 1.00 93.76  ? 226 LYS C C   1 
ATOM 6900 O O   . LYS E 5 226 ? 271.264 328.968 446.022 1.00 93.76  ? 226 LYS C O   1 
ATOM 6901 C CB  . LYS E 5 226 ? 271.859 325.835 447.454 1.00 93.76  ? 226 LYS C CB  1 
ATOM 6902 C CG  . LYS E 5 226 ? 273.073 326.538 448.034 1.00 93.76  ? 226 LYS C CG  1 
ATOM 6903 C CD  . LYS E 5 226 ? 273.410 325.949 449.391 1.00 93.76  ? 226 LYS C CD  1 
ATOM 6904 C CE  . LYS E 5 226 ? 274.853 326.180 449.775 1.00 93.76  ? 226 LYS C CE  1 
ATOM 6905 N NZ  . LYS E 5 226 ? 275.084 327.563 450.237 1.00 93.76  ? 226 LYS C NZ  1 
ATOM 6906 N N   . ASP E 5 227 ? 270.205 328.238 447.854 1.00 100.88 ? 227 ASP C N   1 
ATOM 6907 C CA  . ASP E 5 227 ? 269.968 329.596 448.318 1.00 100.88 ? 227 ASP C CA  1 
ATOM 6908 C C   . ASP E 5 227 ? 271.071 330.050 449.268 1.00 100.88 ? 227 ASP C C   1 
ATOM 6909 O O   . ASP E 5 227 ? 271.809 329.241 449.833 1.00 100.88 ? 227 ASP C O   1 
ATOM 6910 C CB  . ASP E 5 227 ? 268.593 329.716 448.974 1.00 100.88 ? 227 ASP C CB  1 
ATOM 6911 C CG  . ASP E 5 227 ? 268.430 328.832 450.201 1.00 100.88 ? 227 ASP C CG  1 
ATOM 6912 O OD1 . ASP E 5 227 ? 269.268 327.941 450.454 1.00 100.88 ? 227 ASP C OD1 1 
ATOM 6913 O OD2 . ASP E 5 227 ? 267.405 328.995 450.894 1.00 100.88 ? 227 ASP C OD2 1 
ATOM 6914 N N   . THR E 5 228 ? 271.168 331.352 449.440 1.00 98.43  ? 228 THR C N   1 
ATOM 6915 C CA  . THR E 5 228 ? 272.262 331.923 450.203 1.00 98.43  ? 228 THR C CA  1 
ATOM 6916 C C   . THR E 5 228 ? 271.948 331.931 451.695 1.00 98.43  ? 228 THR C C   1 
ATOM 6917 O O   . THR E 5 228 ? 270.791 332.058 452.093 1.00 98.43  ? 228 THR C O   1 
ATOM 6918 C CB  . THR E 5 228 ? 272.549 333.339 449.727 1.00 98.43  ? 228 THR C CB  1 
ATOM 6919 O OG1 . THR E 5 228 ? 273.447 333.979 450.639 1.00 98.43  ? 228 THR C OG1 1 
ATOM 6920 C CG2 . THR E 5 228 ? 271.270 334.141 449.617 1.00 98.43  ? 228 THR C CG2 1 
ATOM 6921 N N   . PRO E 5 229 ? 272.959 331.761 452.543 1.00 97.65  ? 229 PRO C N   1 
ATOM 6922 C CA  . PRO E 5 229 ? 272.751 331.876 453.992 1.00 97.65  ? 229 PRO C CA  1 
ATOM 6923 C C   . PRO E 5 229 ? 272.939 333.273 454.563 1.00 97.65  ? 229 PRO C C   1 
ATOM 6924 O O   . PRO E 5 229 ? 272.907 333.418 455.788 1.00 97.65  ? 229 PRO C O   1 
ATOM 6925 C CB  . PRO E 5 229 ? 273.822 330.932 454.547 1.00 97.65  ? 229 PRO C CB  1 
ATOM 6926 C CG  . PRO E 5 229 ? 274.912 331.021 453.572 1.00 97.65  ? 229 PRO C CG  1 
ATOM 6927 C CD  . PRO E 5 229 ? 274.269 331.171 452.228 1.00 97.65  ? 229 PRO C CD  1 
ATOM 6928 N N   . PHE E 5 230 ? 273.124 334.294 453.735 1.00 98.66  ? 230 PHE C N   1 
ATOM 6929 C CA  . PHE E 5 230 ? 273.296 335.664 454.220 1.00 98.66  ? 230 PHE C CA  1 
ATOM 6930 C C   . PHE E 5 230 ? 271.955 336.389 454.266 1.00 98.66  ? 230 PHE C C   1 
ATOM 6931 O O   . PHE E 5 230 ? 271.775 337.469 453.710 1.00 98.66  ? 230 PHE C O   1 
ATOM 6932 C CB  . PHE E 5 230 ? 274.287 336.414 453.344 1.00 98.66  ? 230 PHE C CB  1 
ATOM 6933 C CG  . PHE E 5 230 ? 275.651 335.824 453.348 1.00 98.66  ? 230 PHE C CG  1 
ATOM 6934 C CD1 . PHE E 5 230 ? 276.203 335.342 454.518 1.00 98.66  ? 230 PHE C CD1 1 
ATOM 6935 C CD2 . PHE E 5 230 ? 276.379 335.736 452.178 1.00 98.66  ? 230 PHE C CD2 1 
ATOM 6936 C CE1 . PHE E 5 230 ? 277.459 334.791 454.522 1.00 98.66  ? 230 PHE C CE1 1 
ATOM 6937 C CE2 . PHE E 5 230 ? 277.631 335.186 452.175 1.00 98.66  ? 230 PHE C CE2 1 
ATOM 6938 C CZ  . PHE E 5 230 ? 278.173 334.711 453.348 1.00 98.66  ? 230 PHE C CZ  1 
ATOM 6939 N N   . ILE E 5 231 ? 270.999 335.769 454.953 1.00 107.44 ? 231 ILE C N   1 
ATOM 6940 C CA  . ILE E 5 231 ? 269.644 336.291 455.040 1.00 107.44 ? 231 ILE C CA  1 
ATOM 6941 C C   . ILE E 5 231 ? 269.049 335.797 456.351 1.00 107.44 ? 231 ILE C C   1 
ATOM 6942 O O   . ILE E 5 231 ? 269.608 334.919 457.011 1.00 107.44 ? 231 ILE C O   1 
ATOM 6943 C CB  . ILE E 5 231 ? 268.815 335.873 453.801 1.00 107.44 ? 231 ILE C CB  1 
ATOM 6944 C CG1 . ILE E 5 231 ? 267.840 336.979 453.426 1.00 107.44 ? 231 ILE C CG1 1 
ATOM 6945 C CG2 . ILE E 5 231 ? 268.120 334.535 454.008 1.00 107.44 ? 231 ILE C CG2 1 
ATOM 6946 C CD1 . ILE E 5 231 ? 268.540 338.219 452.943 1.00 107.44 ? 231 ILE C CD1 1 
ATOM 6947 N N   . ARG E 5 232 ? 267.933 336.404 456.753 1.00 116.74 ? 232 ARG C N   1 
ATOM 6948 C CA  . ARG E 5 232 ? 267.276 336.112 458.028 1.00 116.74 ? 232 ARG C CA  1 
ATOM 6949 C C   . ARG E 5 232 ? 266.839 334.655 458.186 1.00 116.74 ? 232 ARG C C   1 
ATOM 6950 O O   . ARG E 5 232 ? 266.425 334.013 457.223 1.00 116.74 ? 232 ARG C O   1 
ATOM 6951 C CB  . ARG E 5 232 ? 266.061 337.023 458.197 1.00 116.74 ? 232 ARG C CB  1 
ATOM 6952 C CG  . ARG E 5 232 ? 265.158 337.068 456.973 1.00 116.74 ? 232 ARG C CG  1 
ATOM 6953 C CD  . ARG E 5 232 ? 263.906 336.232 457.173 1.00 116.74 ? 232 ARG C CD  1 
ATOM 6954 N NE  . ARG E 5 232 ? 263.083 336.190 455.971 1.00 116.74 ? 232 ARG C NE  1 
ATOM 6955 C CZ  . ARG E 5 232 ? 262.010 335.420 455.831 1.00 116.74 ? 232 ARG C CZ  1 
ATOM 6956 N NH1 . ARG E 5 232 ? 261.631 334.626 456.824 1.00 116.74 ? 232 ARG C NH1 1 
ATOM 6957 N NH2 . ARG E 5 232 ? 261.318 335.443 454.701 1.00 116.74 ? 232 ARG C NH2 1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   LYS 3   3   3   LYS LYS H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  GLN 13  13  13  GLN GLN H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  SER 19  19  19  SER SER H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  ALA 23  23  23  ALA ALA H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  THR 28  28  28  THR THR H . n 
A 1 29  PHE 29  29  29  PHE PHE H . n 
A 1 30  THR 30  30  30  THR THR H . n 
A 1 31  ASP 31  31  31  ASP ASP H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  TYR 33  33  33  TYR TYR H . n 
A 1 34  MET 34  34  34  MET MET H . n 
A 1 35  ASN 35  35  35  ASN ASN H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  PRO 40  40  40  PRO PRO H . n 
A 1 41  SER 41  41  41  SER SER H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  ALA 44  44  44  ALA ALA H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  TRP 47  47  47  TRP TRP H . n 
A 1 48  LEU 48  48  48  LEU LEU H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  PHE 50  50  50  PHE PHE H . n 
A 1 51  LEU 51  51  51  LEU LEU H . n 
A 1 52  ARG 52  52  52  ARG ARG H . n 
A 1 53  ASN 53  53  53  ASN ASN H . n 
A 1 54  LYS 54  54  54  LYS LYS H . n 
A 1 55  ALA 55  55  55  ALA ALA H . n 
A 1 56  ASN 56  56  56  ASN ASN H . n 
A 1 57  GLY 57  57  57  GLY GLY H . n 
A 1 58  TYR 58  58  58  TYR TYR H . n 
A 1 59  THR 59  59  59  THR THR H . n 
A 1 60  THR 60  60  60  THR THR H . n 
A 1 61  GLU 61  61  61  GLU GLU H . n 
A 1 62  TYR 62  62  62  TYR TYR H . n 
A 1 63  SER 63  63  63  SER SER H . n 
A 1 64  ALA 64  64  64  ALA ALA H . n 
A 1 65  SER 65  65  65  SER SER H . n 
A 1 66  VAL 66  66  66  VAL VAL H . n 
A 1 67  LYS 67  67  67  LYS LYS H . n 
A 1 68  GLY 68  68  68  GLY GLY H . n 
A 1 69  ARG 69  69  69  ARG ARG H . n 
A 1 70  PHE 70  70  70  PHE PHE H . n 
A 1 71  THR 71  71  71  THR THR H . n 
A 1 72  ILE 72  72  72  ILE ILE H . n 
A 1 73  SER 73  73  73  SER SER H . n 
A 1 74  ARG 74  74  74  ARG ARG H . n 
A 1 75  ASP 75  75  75  ASP ASP H . n 
A 1 76  ASN 76  76  76  ASN ASN H . n 
A 1 77  SER 77  77  77  SER SER H . n 
A 1 78  GLN 78  78  78  GLN GLN H . n 
A 1 79  SER 79  79  79  SER SER H . n 
A 1 80  ILE 80  80  80  ILE ILE H . n 
A 1 81  LEU 81  81  81  LEU LEU H . n 
A 1 82  TYR 82  82  82  TYR TYR H . n 
A 1 83  LEU 83  83  83  LEU LEU H . n 
A 1 84  GLN 84  84  84  GLN GLN H . n 
A 1 85  MET 85  85  85  MET MET H . n 
A 1 86  ASN 86  86  86  ASN ASN H . n 
A 1 87  ALA 87  87  87  ALA ALA H . n 
A 1 88  LEU 88  88  88  LEU LEU H . n 
A 1 89  ARG 89  89  89  ARG ARG H . n 
A 1 90  ALA 90  90  90  ALA ALA H . n 
A 1 91  GLU 91  91  91  GLU GLU H . n 
A 1 92  ASP 92  92  92  ASP ASP H . n 
A 1 93  SER 93  93  93  SER SER H . n 
A 1 94  ALA 94  94  94  ALA ALA H . n 
A 1 95  THR 95  95  95  THR THR H . n 
A 1 96  TYR 96  96  96  TYR TYR H . n 
A 1 97  TYR 97  97  97  TYR TYR H . n 
A 1 98  CYS 98  98  98  CYS CYS H . n 
A 1 99  ALA 99  99  99  ALA ALA H . n 
A 1 100 ARG 100 100 100 ARG ARG H . n 
A 1 101 SER 101 101 101 SER SER H . n 
A 1 102 ARG 102 102 102 ARG ARG H . n 
A 1 103 TYR 103 103 103 TYR TYR H . n 
A 1 104 TYR 104 104 104 TYR TYR H . n 
A 1 105 GLY 105 105 105 GLY GLY H . n 
A 1 106 GLY 106 106 106 GLY GLY H . n 
A 1 107 THR 107 107 107 THR THR H . n 
A 1 108 TYR 108 108 108 TYR TYR H . n 
A 1 109 ARG 109 109 109 ARG ARG H . n 
A 1 110 TYR 110 110 110 TYR TYR H . n 
A 1 111 ALA 111 111 111 ALA ALA H . n 
A 1 112 LEU 112 112 112 LEU LEU H . n 
A 1 113 ASP 113 113 113 ASP ASP H . n 
A 1 114 TYR 114 114 114 TYR TYR H . n 
A 1 115 TRP 115 115 115 TRP TRP H . n 
A 1 116 GLY 116 116 116 GLY GLY H . n 
A 1 117 GLN 117 117 117 GLN GLN H . n 
A 1 118 GLY 118 118 118 GLY GLY H . n 
A 1 119 THR 119 119 119 THR THR H . n 
A 1 120 SER 120 120 120 SER SER H . n 
A 1 121 VAL 121 121 121 VAL VAL H . n 
A 1 122 THR 122 122 122 THR THR H . n 
A 1 123 VAL 123 123 123 VAL VAL H . n 
A 1 124 SER 124 124 124 SER SER H . n 
B 2 1   GLU 1   1   ?   ?   ?   L . n 
B 2 2   ASN 2   2   2   ASN ASN L . n 
B 2 3   VAL 3   3   3   VAL VAL L . n 
B 2 4   LEU 4   4   4   LEU LEU L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   PRO 9   9   9   PRO PRO L . n 
B 2 10  ILE 10  10  10  ILE ILE L . n 
B 2 11  MET 11  11  11  MET MET L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  PRO 15  15  15  PRO PRO L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  GLU 17  17  17  GLU GLU L . n 
B 2 18  LYS 18  18  18  LYS LYS L . n 
B 2 19  VAL 19  19  19  VAL VAL L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  MET 21  21  21  MET MET L . n 
B 2 22  THR 22  22  22  THR THR L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  SER 27  27  27  SER SER L . n 
B 2 28  SER 28  28  28  SER SER L . n 
B 2 29  VAL 29  29  29  VAL VAL L . n 
B 2 30  SER 30  30  30  SER SER L . n 
B 2 31  SER 31  31  31  SER SER L . n 
B 2 32  SER 32  32  32  SER SER L . n 
B 2 33  TYR 33  33  33  TYR TYR L . n 
B 2 34  LEU 34  34  34  LEU LEU L . n 
B 2 35  HIS 35  35  35  HIS HIS L . n 
B 2 36  TRP 36  36  36  TRP TRP L . n 
B 2 37  TYR 37  37  37  TYR TYR L . n 
B 2 38  GLN 38  38  38  GLN GLN L . n 
B 2 39  GLN 39  39  39  GLN GLN L . n 
B 2 40  LYS 40  40  40  LYS LYS L . n 
B 2 41  SER 41  41  41  SER SER L . n 
B 2 42  GLY 42  42  42  GLY GLY L . n 
B 2 43  ALA 43  43  43  ALA ALA L . n 
B 2 44  SER 44  44  44  SER SER L . n 
B 2 45  PRO 45  45  45  PRO PRO L . n 
B 2 46  LYS 46  46  46  LYS LYS L . n 
B 2 47  LEU 47  47  47  LEU LEU L . n 
B 2 48  TRP 48  48  48  TRP TRP L . n 
B 2 49  ILE 49  49  49  ILE ILE L . n 
B 2 50  TYR 50  50  50  TYR TYR L . n 
B 2 51  SER 51  51  51  SER SER L . n 
B 2 52  THR 52  52  52  THR THR L . n 
B 2 53  SER 53  53  53  SER SER L . n 
B 2 54  ASN 54  54  54  ASN ASN L . n 
B 2 55  LEU 55  55  55  LEU LEU L . n 
B 2 56  ALA 56  56  56  ALA ALA L . n 
B 2 57  SER 57  57  57  SER SER L . n 
B 2 58  GLY 58  58  58  GLY GLY L . n 
B 2 59  VAL 59  59  59  VAL VAL L . n 
B 2 60  PRO 60  60  60  PRO PRO L . n 
B 2 61  ALA 61  61  61  ALA ALA L . n 
B 2 62  ARG 62  62  62  ARG ARG L . n 
B 2 63  PHE 63  63  63  PHE PHE L . n 
B 2 64  SER 64  64  64  SER SER L . n 
B 2 65  GLY 65  65  65  GLY GLY L . n 
B 2 66  SER 66  66  66  SER SER L . n 
B 2 67  GLY 67  67  67  GLY GLY L . n 
B 2 68  SER 68  68  68  SER SER L . n 
B 2 69  GLY 69  69  69  GLY GLY L . n 
B 2 70  THR 70  70  70  THR THR L . n 
B 2 71  SER 71  71  71  SER SER L . n 
B 2 72  TYR 72  72  72  TYR TYR L . n 
B 2 73  SER 73  73  73  SER SER L . n 
B 2 74  LEU 74  74  74  LEU LEU L . n 
B 2 75  THR 75  75  75  THR THR L . n 
B 2 76  ILE 76  76  76  ILE ILE L . n 
B 2 77  SER 77  77  77  SER SER L . n 
B 2 78  SER 78  78  78  SER SER L . n 
B 2 79  VAL 79  79  79  VAL VAL L . n 
B 2 80  GLU 80  80  80  GLU GLU L . n 
B 2 81  ALA 81  81  81  ALA ALA L . n 
B 2 82  GLU 82  82  82  GLU GLU L . n 
B 2 83  ASP 83  83  83  ASP ASP L . n 
B 2 84  ALA 84  84  84  ALA ALA L . n 
B 2 85  ALA 85  85  85  ALA ALA L . n 
B 2 86  THR 86  86  86  THR THR L . n 
B 2 87  TYR 87  87  87  TYR TYR L . n 
B 2 88  TYR 88  88  88  TYR TYR L . n 
B 2 89  CYS 89  89  89  CYS CYS L . n 
B 2 90  GLN 90  90  90  GLN GLN L . n 
B 2 91  GLN 91  91  91  GLN GLN L . n 
B 2 92  PHE 92  92  92  PHE PHE L . n 
B 2 93  SER 93  93  93  SER SER L . n 
B 2 94  GLY 94  94  94  GLY GLY L . n 
B 2 95  TYR 95  95  95  TYR TYR L . n 
B 2 96  PRO 96  96  96  PRO PRO L . n 
B 2 97  LEU 97  97  97  LEU LEU L . n 
B 2 98  THR 98  98  98  THR THR L . n 
B 2 99  PHE 99  99  99  PHE PHE L . n 
B 2 100 GLY 100 100 100 GLY GLY L . n 
B 2 101 ALA 101 101 101 ALA ALA L . n 
B 2 102 GLY 102 102 102 GLY GLY L . n 
B 2 103 THR 103 103 103 THR THR L . n 
B 2 104 LYS 104 104 104 LYS LYS L . n 
B 2 105 LEU 105 105 105 LEU LEU L . n 
B 2 106 GLU 106 106 106 GLU GLU L . n 
B 2 107 LEU 107 107 107 LEU LEU L . n 
B 2 108 LYS 108 108 108 LYS LYS L . n 
C 3 1   GLY 1   1   ?   ?   ?   A . n 
C 3 2   PRO 2   2   ?   ?   ?   A . n 
C 3 3   VAL 3   3   ?   ?   ?   A . n 
C 3 4   GLU 4   4   ?   ?   ?   A . n 
C 3 5   GLU 5   5   ?   ?   ?   A . n 
C 3 6   SER 6   6   ?   ?   ?   A . n 
C 3 7   VAL 7   7   ?   ?   ?   A . n 
C 3 8   ASP 8   8   ?   ?   ?   A . n 
C 3 9   ARG 9   9   ?   ?   ?   A . n 
C 3 10  ALA 10  10  ?   ?   ?   A . n 
C 3 11  VAL 11  11  ?   ?   ?   A . n 
C 3 12  ALA 12  12  ?   ?   ?   A . n 
C 3 13  ARG 13  13  ?   ?   ?   A . n 
C 3 14  VAL 14  14  ?   ?   ?   A . n 
C 3 15  ALA 15  15  ?   ?   ?   A . n 
C 3 16  ASP 16  16  ?   ?   ?   A . n 
C 3 17  THR 17  17  ?   ?   ?   A . n 
C 3 18  ILE 18  18  ?   ?   ?   A . n 
C 3 19  SER 19  19  ?   ?   ?   A . n 
C 3 20  SER 20  20  ?   ?   ?   A . n 
C 3 21  ARG 21  21  ?   ?   ?   A . n 
C 3 22  PRO 22  22  ?   ?   ?   A . n 
C 3 23  THR 23  23  ?   ?   ?   A . n 
C 3 24  ASN 24  24  ?   ?   ?   A . n 
C 3 25  SER 25  25  ?   ?   ?   A . n 
C 3 26  GLU 26  26  ?   ?   ?   A . n 
C 3 27  SER 27  27  ?   ?   ?   A . n 
C 3 28  ILE 28  28  ?   ?   ?   A . n 
C 3 29  PRO 29  29  ?   ?   ?   A . n 
C 3 30  ALA 30  30  ?   ?   ?   A . n 
C 3 31  LEU 31  31  ?   ?   ?   A . n 
C 3 32  THR 32  32  ?   ?   ?   A . n 
C 3 33  ALA 33  33  ?   ?   ?   A . n 
C 3 34  ALA 34  34  ?   ?   ?   A . n 
C 3 35  GLU 35  35  ?   ?   ?   A . n 
C 3 36  THR 36  36  ?   ?   ?   A . n 
C 3 37  GLY 37  37  ?   ?   ?   A . n 
C 3 38  HIS 38  38  ?   ?   ?   A . n 
C 3 39  THR 39  39  ?   ?   ?   A . n 
C 3 40  SER 40  40  ?   ?   ?   A . n 
C 3 41  GLN 41  41  ?   ?   ?   A . n 
C 3 42  VAL 42  42  ?   ?   ?   A . n 
C 3 43  VAL 43  43  ?   ?   ?   A . n 
C 3 44  PRO 44  44  ?   ?   ?   A . n 
C 3 45  SER 45  45  ?   ?   ?   A . n 
C 3 46  ASP 46  46  ?   ?   ?   A . n 
C 3 47  THR 47  47  ?   ?   ?   A . n 
C 3 48  MET 48  48  ?   ?   ?   A . n 
C 3 49  GLN 49  49  ?   ?   ?   A . n 
C 3 50  THR 50  50  ?   ?   ?   A . n 
C 3 51  ARG 51  51  ?   ?   ?   A . n 
C 3 52  HIS 52  52  ?   ?   ?   A . n 
C 3 53  VAL 53  53  ?   ?   ?   A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ASN 55  55  ?   ?   ?   A . n 
C 3 56  TYR 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  SER 58  58  58  SER SER A . n 
C 3 59  ARG 59  59  59  ARG ARG A . n 
C 3 60  SER 60  60  60  SER SER A . n 
C 3 61  GLU 61  61  61  GLU GLU A . n 
C 3 62  SER 62  62  62  SER SER A . n 
C 3 63  SER 63  63  63  SER SER A . n 
C 3 64  ILE 64  64  64  ILE ILE A . n 
C 3 65  GLU 65  65  65  GLU GLU A . n 
C 3 66  ASN 66  66  66  ASN ASN A . n 
C 3 67  PHE 67  67  67  PHE PHE A . n 
C 3 68  LEU 68  68  68  LEU LEU A . n 
C 3 69  CYS 69  69  69  CYS CYS A . n 
C 3 70  ARG 70  70  70  ARG ARG A . n 
C 3 71  SER 71  71  71  SER SER A . n 
C 3 72  ALA 72  72  72  ALA ALA A . n 
C 3 73  CYS 73  73  73  CYS CYS A . n 
C 3 74  VAL 74  74  74  VAL VAL A . n 
C 3 75  TYR 75  75  75  TYR TYR A . n 
C 3 76  TYR 76  76  76  TYR TYR A . n 
C 3 77  ALA 77  77  77  ALA ALA A . n 
C 3 78  THR 78  78  78  THR THR A . n 
C 3 79  TYR 79  79  79  TYR TYR A . n 
C 3 80  THR 80  80  80  THR THR A . n 
C 3 81  ASN 81  81  81  ASN ASN A . n 
C 3 82  ASN 82  82  82  ASN ASN A . n 
C 3 83  SER 83  83  83  SER SER A . n 
C 3 84  LYS 84  84  84  LYS LYS A . n 
C 3 85  LYS 85  85  85  LYS LYS A . n 
C 3 86  GLY 86  86  86  GLY GLY A . n 
C 3 87  PHE 87  87  87  PHE PHE A . n 
C 3 88  ALA 88  88  88  ALA ALA A . n 
C 3 89  GLU 89  89  89  GLU GLU A . n 
C 3 90  TRP 90  90  90  TRP TRP A . n 
C 3 91  VAL 91  91  91  VAL VAL A . n 
C 3 92  ILE 92  92  92  ILE ILE A . n 
C 3 93  ASN 93  93  93  ASN ASN A . n 
C 3 94  THR 94  94  94  THR THR A . n 
C 3 95  ARG 95  95  95  ARG ARG A . n 
C 3 96  GLN 96  96  96  GLN GLN A . n 
C 3 97  VAL 97  97  97  VAL VAL A . n 
C 3 98  ALA 98  98  98  ALA ALA A . n 
C 3 99  GLN 99  99  99  GLN GLN A . n 
C 3 100 LEU 100 100 100 LEU LEU A . n 
C 3 101 ARG 101 101 101 ARG ARG A . n 
C 3 102 ARG 102 102 102 ARG ARG A . n 
C 3 103 LYS 103 103 103 LYS LYS A . n 
C 3 104 LEU 104 104 104 LEU LEU A . n 
C 3 105 GLU 105 105 105 GLU GLU A . n 
C 3 106 LEU 106 106 106 LEU LEU A . n 
C 3 107 PHE 107 107 107 PHE PHE A . n 
C 3 108 THR 108 108 108 THR THR A . n 
C 3 109 TYR 109 109 109 TYR TYR A . n 
C 3 110 LEU 110 110 110 LEU LEU A . n 
C 3 111 ARG 111 111 111 ARG ARG A . n 
C 3 112 PHE 112 112 112 PHE PHE A . n 
C 3 113 ASP 113 113 113 ASP ASP A . n 
C 3 114 LEU 114 114 114 LEU LEU A . n 
C 3 115 GLU 115 115 115 GLU GLU A . n 
C 3 116 LEU 116 116 116 LEU LEU A . n 
C 3 117 THR 117 117 117 THR THR A . n 
C 3 118 PHE 118 118 118 PHE PHE A . n 
C 3 119 VAL 119 119 119 VAL VAL A . n 
C 3 120 ILE 120 120 120 ILE ILE A . n 
C 3 121 THR 121 121 121 THR THR A . n 
C 3 122 SER 122 122 122 SER SER A . n 
C 3 123 ALA 123 123 123 ALA ALA A . n 
C 3 124 GLN 124 124 124 GLN GLN A . n 
C 3 125 GLN 125 125 125 GLN GLN A . n 
C 3 126 PRO 126 126 126 PRO PRO A . n 
C 3 127 SER 127 127 127 SER SER A . n 
C 3 128 THR 128 128 128 THR THR A . n 
C 3 129 ALA 129 129 129 ALA ALA A . n 
C 3 130 SER 130 130 130 SER SER A . n 
C 3 131 SER 131 131 131 SER SER A . n 
C 3 132 VAL 132 132 132 VAL VAL A . n 
C 3 133 ASP 133 133 133 ASP ASP A . n 
C 3 134 ALA 134 134 134 ALA ALA A . n 
C 3 135 PRO 135 135 135 PRO PRO A . n 
C 3 136 VAL 136 136 136 VAL VAL A . n 
C 3 137 GLN 137 137 137 GLN GLN A . n 
C 3 138 THR 138 138 138 THR THR A . n 
C 3 139 HIS 139 139 139 HIS HIS A . n 
C 3 140 GLN 140 140 140 GLN GLN A . n 
C 3 141 ILE 141 141 141 ILE ILE A . n 
C 3 142 MET 142 142 142 MET MET A . n 
C 3 143 TYR 143 143 143 TYR TYR A . n 
C 3 144 VAL 144 144 144 VAL VAL A . n 
C 3 145 PRO 145 145 145 PRO PRO A . n 
C 3 146 PRO 146 146 146 PRO PRO A . n 
C 3 147 GLY 147 147 147 GLY GLY A . n 
C 3 148 GLY 148 148 148 GLY GLY A . n 
C 3 149 PRO 149 149 149 PRO PRO A . n 
C 3 150 VAL 150 150 150 VAL VAL A . n 
C 3 151 PRO 151 151 151 PRO PRO A . n 
C 3 152 THR 152 152 152 THR THR A . n 
C 3 153 LYS 153 153 153 LYS LYS A . n 
C 3 154 VAL 154 154 154 VAL VAL A . n 
C 3 155 LYS 155 155 155 LYS LYS A . n 
C 3 156 ASP 156 156 156 ASP ASP A . n 
C 3 157 TYR 157 157 157 TYR TYR A . n 
C 3 158 ALA 158 158 158 ALA ALA A . n 
C 3 159 TRP 159 159 159 TRP TRP A . n 
C 3 160 GLN 160 160 160 GLN GLN A . n 
C 3 161 THR 161 161 161 THR THR A . n 
C 3 162 SER 162 162 162 SER SER A . n 
C 3 163 THR 163 163 163 THR THR A . n 
C 3 164 ASN 164 164 164 ASN ASN A . n 
C 3 165 PRO 165 165 165 PRO PRO A . n 
C 3 166 SER 166 166 166 SER SER A . n 
C 3 167 VAL 167 167 167 VAL VAL A . n 
C 3 168 PHE 168 168 168 PHE PHE A . n 
C 3 169 TRP 169 169 169 TRP TRP A . n 
C 3 170 THR 170 170 170 THR THR A . n 
C 3 171 GLU 171 171 171 GLU GLU A . n 
C 3 172 GLY 172 172 172 GLY GLY A . n 
C 3 173 ASN 173 173 173 ASN ASN A . n 
C 3 174 ALA 174 174 174 ALA ALA A . n 
C 3 175 PRO 175 175 175 PRO PRO A . n 
C 3 176 PRO 176 176 176 PRO PRO A . n 
C 3 177 ARG 177 177 177 ARG ARG A . n 
C 3 178 MET 178 178 178 MET MET A . n 
C 3 179 SER 179 179 179 SER SER A . n 
C 3 180 ILE 180 180 180 ILE ILE A . n 
C 3 181 PRO 181 181 181 PRO PRO A . n 
C 3 182 PHE 182 182 182 PHE PHE A . n 
C 3 183 ILE 183 183 183 ILE ILE A . n 
C 3 184 SER 184 184 184 SER SER A . n 
C 3 185 ILE 185 185 185 ILE ILE A . n 
C 3 186 GLY 186 186 186 GLY GLY A . n 
C 3 187 ASN 187 187 187 ASN ASN A . n 
C 3 188 ALA 188 188 188 ALA ALA A . n 
C 3 189 TYR 189 189 189 TYR TYR A . n 
C 3 190 SER 190 190 190 SER SER A . n 
C 3 191 CYS 191 191 191 CYS CYS A . n 
C 3 192 PHE 192 192 192 PHE PHE A . n 
C 3 193 TYR 193 193 193 TYR TYR A . n 
C 3 194 ASP 194 194 194 ASP ASP A . n 
C 3 195 GLY 195 195 195 GLY GLY A . n 
C 3 196 TRP 196 196 196 TRP TRP A . n 
C 3 197 THR 197 197 197 THR THR A . n 
C 3 198 GLN 198 198 ?   ?   ?   A . n 
C 3 199 PHE 199 199 ?   ?   ?   A . n 
C 3 200 SER 200 200 ?   ?   ?   A . n 
C 3 201 ARG 201 201 ?   ?   ?   A . n 
C 3 202 ASN 202 202 ?   ?   ?   A . n 
C 3 203 GLY 203 203 ?   ?   ?   A . n 
C 3 204 VAL 204 204 204 VAL VAL A . n 
C 3 205 TYR 205 205 205 TYR TYR A . n 
C 3 206 GLY 206 206 206 GLY GLY A . n 
C 3 207 ILE 207 207 207 ILE ILE A . n 
C 3 208 ASN 208 208 208 ASN ASN A . n 
C 3 209 THR 209 209 209 THR THR A . n 
C 3 210 LEU 210 210 210 LEU LEU A . n 
C 3 211 ASN 211 211 211 ASN ASN A . n 
C 3 212 ASN 212 212 212 ASN ASN A . n 
C 3 213 MET 213 213 213 MET MET A . n 
C 3 214 GLY 214 214 214 GLY GLY A . n 
C 3 215 THR 215 215 215 THR THR A . n 
C 3 216 LEU 216 216 216 LEU LEU A . n 
C 3 217 TYR 217 217 217 TYR TYR A . n 
C 3 218 MET 218 218 218 MET MET A . n 
C 3 219 ARG 219 219 219 ARG ARG A . n 
C 3 220 HIS 220 220 220 HIS HIS A . n 
C 3 221 VAL 221 221 221 VAL VAL A . n 
C 3 222 ASN 222 222 222 ASN ASN A . n 
C 3 223 GLU 223 223 223 GLU GLU A . n 
C 3 224 ALA 224 224 224 ALA ALA A . n 
C 3 225 GLY 225 225 225 GLY GLY A . n 
C 3 226 GLN 226 226 226 GLN GLN A . n 
C 3 227 GLY 227 227 227 GLY GLY A . n 
C 3 228 PRO 228 228 228 PRO PRO A . n 
C 3 229 ILE 229 229 229 ILE ILE A . n 
C 3 230 LYS 230 230 230 LYS LYS A . n 
C 3 231 SER 231 231 231 SER SER A . n 
C 3 232 THR 232 232 232 THR THR A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 ARG 234 234 234 ARG ARG A . n 
C 3 235 ILE 235 235 235 ILE ILE A . n 
C 3 236 TYR 236 236 236 TYR TYR A . n 
C 3 237 PHE 237 237 237 PHE PHE A . n 
C 3 238 LYS 238 238 238 LYS LYS A . n 
C 3 239 PRO 239 239 239 PRO PRO A . n 
C 3 240 LYS 240 240 240 LYS LYS A . n 
C 3 241 HIS 241 241 241 HIS HIS A . n 
C 3 242 VAL 242 242 242 VAL VAL A . n 
C 3 243 LYS 243 243 243 LYS LYS A . n 
C 3 244 ALA 244 244 244 ALA ALA A . n 
C 3 245 TRP 245 245 245 TRP TRP A . n 
C 3 246 VAL 246 246 246 VAL VAL A . n 
C 3 247 PRO 247 247 247 PRO PRO A . n 
C 3 248 ARG 248 248 248 ARG ARG A . n 
C 3 249 PRO 249 249 249 PRO PRO A . n 
C 3 250 PRO 250 250 250 PRO PRO A . n 
C 3 251 ARG 251 251 251 ARG ARG A . n 
C 3 252 LEU 252 252 252 LEU LEU A . n 
C 3 253 CYS 253 253 253 CYS CYS A . n 
C 3 254 GLN 254 254 254 GLN GLN A . n 
C 3 255 TYR 255 255 255 TYR TYR A . n 
C 3 256 GLU 256 256 256 GLU GLU A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 GLN 258 258 258 GLN GLN A . n 
C 3 259 LYS 259 259 259 LYS LYS A . n 
C 3 260 ASN 260 260 260 ASN ASN A . n 
C 3 261 VAL 261 261 261 VAL VAL A . n 
C 3 262 ASN 262 262 262 ASN ASN A . n 
C 3 263 PHE 263 263 263 PHE PHE A . n 
C 3 264 SER 264 264 264 SER SER A . n 
C 3 265 PRO 265 265 265 PRO PRO A . n 
C 3 266 ILE 266 266 266 ILE ILE A . n 
C 3 267 GLY 267 267 267 GLY GLY A . n 
C 3 268 VAL 268 268 268 VAL VAL A . n 
C 3 269 THR 269 269 269 THR THR A . n 
C 3 270 THR 270 270 270 THR THR A . n 
C 3 271 SER 271 271 271 SER SER A . n 
C 3 272 ARG 272 272 272 ARG ARG A . n 
C 3 273 THR 273 273 273 THR THR A . n 
C 3 274 ASP 274 274 274 ASP ASP A . n 
C 3 275 ILE 275 275 275 ILE ILE A . n 
C 3 276 ILE 276 276 276 ILE ILE A . n 
C 3 277 THR 277 277 ?   ?   ?   A . n 
C 3 278 THR 278 278 ?   ?   ?   A . n 
D 4 1   SER 1   1   ?   ?   ?   B . n 
D 4 2   PRO 2   2   ?   ?   ?   B . n 
D 4 3   SER 3   3   ?   ?   ?   B . n 
D 4 4   ALA 4   4   ?   ?   ?   B . n 
D 4 5   GLU 5   5   ?   ?   ?   B . n 
D 4 6   GLU 6   6   ?   ?   ?   B . n 
D 4 7   CYS 7   7   ?   ?   ?   B . n 
D 4 8   GLY 8   8   ?   ?   ?   B . n 
D 4 9   TYR 9   9   ?   ?   ?   B . n 
D 4 10  SER 10  10  ?   ?   ?   B . n 
D 4 11  ASP 11  11  ?   ?   ?   B . n 
D 4 12  ARG 12  12  ?   ?   ?   B . n 
D 4 13  VAL 13  13  ?   ?   ?   B . n 
D 4 14  ARG 14  14  14  ARG ARG B . n 
D 4 15  SER 15  15  15  SER SER B . n 
D 4 16  ILE 16  16  16  ILE ILE B . n 
D 4 17  THR 17  17  17  THR THR B . n 
D 4 18  LEU 18  18  18  LEU LEU B . n 
D 4 19  GLY 19  19  19  GLY GLY B . n 
D 4 20  ASN 20  20  20  ASN ASN B . n 
D 4 21  SER 21  21  21  SER SER B . n 
D 4 22  THR 22  22  22  THR THR B . n 
D 4 23  ILE 23  23  23  ILE ILE B . n 
D 4 24  THR 24  24  24  THR THR B . n 
D 4 25  THR 25  25  25  THR THR B . n 
D 4 26  GLN 26  26  26  GLN GLN B . n 
D 4 27  GLU 27  27  ?   ?   ?   B . n 
D 4 28  CYS 28  28  ?   ?   ?   B . n 
D 4 29  ALA 29  29  ?   ?   ?   B . n 
D 4 30  ASN 30  30  30  ASN ASN B . n 
D 4 31  VAL 31  31  31  VAL VAL B . n 
D 4 32  VAL 32  32  32  VAL VAL B . n 
D 4 33  VAL 33  33  33  VAL VAL B . n 
D 4 34  GLY 34  34  34  GLY GLY B . n 
D 4 35  TYR 35  35  35  TYR TYR B . n 
D 4 36  GLY 36  36  36  GLY GLY B . n 
D 4 37  VAL 37  37  37  VAL VAL B . n 
D 4 38  TRP 38  38  38  TRP TRP B . n 
D 4 39  PRO 39  39  39  PRO PRO B . n 
D 4 40  GLU 40  40  40  GLU GLU B . n 
D 4 41  TYR 41  41  41  TYR TYR B . n 
D 4 42  LEU 42  42  42  LEU LEU B . n 
D 4 43  LYS 43  43  ?   ?   ?   B . n 
D 4 44  ASP 44  44  ?   ?   ?   B . n 
D 4 45  ASN 45  45  ?   ?   ?   B . n 
D 4 46  GLU 46  46  ?   ?   ?   B . n 
D 4 47  ALA 47  47  ?   ?   ?   B . n 
D 4 48  THR 48  48  ?   ?   ?   B . n 
D 4 49  ALA 49  49  ?   ?   ?   B . n 
D 4 50  GLU 50  50  ?   ?   ?   B . n 
D 4 51  ASP 51  51  51  ASP ASP B . n 
D 4 52  GLN 52  52  52  GLN GLN B . n 
D 4 53  PRO 53  53  53  PRO PRO B . n 
D 4 54  THR 54  54  54  THR THR B . n 
D 4 55  GLN 55  55  55  GLN GLN B . n 
D 4 56  PRO 56  56  56  PRO PRO B . n 
D 4 57  ASP 57  57  57  ASP ASP B . n 
D 4 58  VAL 58  58  58  VAL VAL B . n 
D 4 59  ALA 59  59  59  ALA ALA B . n 
D 4 60  THR 60  60  60  THR THR B . n 
D 4 61  CYS 61  61  61  CYS CYS B . n 
D 4 62  ARG 62  62  62  ARG ARG B . n 
D 4 63  PHE 63  63  63  PHE PHE B . n 
D 4 64  TYR 64  64  64  TYR TYR B . n 
D 4 65  THR 65  65  65  THR THR B . n 
D 4 66  LEU 66  66  66  LEU LEU B . n 
D 4 67  GLU 67  67  67  GLU GLU B . n 
D 4 68  SER 68  68  68  SER SER B . n 
D 4 69  VAL 69  69  69  VAL VAL B . n 
D 4 70  GLN 70  70  70  GLN GLN B . n 
D 4 71  TRP 71  71  71  TRP TRP B . n 
D 4 72  MET 72  72  72  MET MET B . n 
D 4 73  LYS 73  73  73  LYS LYS B . n 
D 4 74  ASN 74  74  74  ASN ASN B . n 
D 4 75  SER 75  75  75  SER SER B . n 
D 4 76  ALA 76  76  76  ALA ALA B . n 
D 4 77  GLY 77  77  77  GLY GLY B . n 
D 4 78  TRP 78  78  78  TRP TRP B . n 
D 4 79  TRP 79  79  79  TRP TRP B . n 
D 4 80  TRP 80  80  80  TRP TRP B . n 
D 4 81  LYS 81  81  81  LYS LYS B . n 
D 4 82  LEU 82  82  82  LEU LEU B . n 
D 4 83  PRO 83  83  83  PRO PRO B . n 
D 4 84  ASP 84  84  84  ASP ASP B . n 
D 4 85  ALA 85  85  85  ALA ALA B . n 
D 4 86  LEU 86  86  86  LEU LEU B . n 
D 4 87  SER 87  87  87  SER SER B . n 
D 4 88  GLN 88  88  88  GLN GLN B . n 
D 4 89  MET 89  89  89  MET MET B . n 
D 4 90  GLY 90  90  90  GLY GLY B . n 
D 4 91  LEU 91  91  91  LEU LEU B . n 
D 4 92  PHE 92  92  92  PHE PHE B . n 
D 4 93  GLY 93  93  93  GLY GLY B . n 
D 4 94  GLN 94  94  94  GLN GLN B . n 
D 4 95  ASN 95  95  95  ASN ASN B . n 
D 4 96  MET 96  96  96  MET MET B . n 
D 4 97  GLN 97  97  97  GLN GLN B . n 
D 4 98  TYR 98  98  98  TYR TYR B . n 
D 4 99  HIS 99  99  99  HIS HIS B . n 
D 4 100 TYR 100 100 100 TYR TYR B . n 
D 4 101 LEU 101 101 101 LEU LEU B . n 
D 4 102 GLY 102 102 102 GLY GLY B . n 
D 4 103 ARG 103 103 103 ARG ARG B . n 
D 4 104 THR 104 104 104 THR THR B . n 
D 4 105 GLY 105 105 105 GLY GLY B . n 
D 4 106 TYR 106 106 106 TYR TYR B . n 
D 4 107 THR 107 107 107 THR THR B . n 
D 4 108 ILE 108 108 108 ILE ILE B . n 
D 4 109 HIS 109 109 109 HIS HIS B . n 
D 4 110 VAL 110 110 110 VAL VAL B . n 
D 4 111 GLN 111 111 111 GLN GLN B . n 
D 4 112 CYS 112 112 112 CYS CYS B . n 
D 4 113 ASN 113 113 113 ASN ASN B . n 
D 4 114 ALA 114 114 114 ALA ALA B . n 
D 4 115 SER 115 115 115 SER SER B . n 
D 4 116 LYS 116 116 116 LYS LYS B . n 
D 4 117 PHE 117 117 117 PHE PHE B . n 
D 4 118 HIS 118 118 118 HIS HIS B . n 
D 4 119 GLN 119 119 119 GLN GLN B . n 
D 4 120 GLY 120 120 120 GLY GLY B . n 
D 4 121 CYS 121 121 121 CYS CYS B . n 
D 4 122 LEU 122 122 122 LEU LEU B . n 
D 4 123 LEU 123 123 123 LEU LEU B . n 
D 4 124 VAL 124 124 124 VAL VAL B . n 
D 4 125 VAL 125 125 125 VAL VAL B . n 
D 4 126 CYS 126 126 126 CYS CYS B . n 
D 4 127 VAL 127 127 127 VAL VAL B . n 
D 4 128 PRO 128 128 128 PRO PRO B . n 
D 4 129 GLU 129 129 129 GLU GLU B . n 
D 4 130 ALA 130 130 130 ALA ALA B . n 
D 4 131 GLU 131 131 131 GLU GLU B . n 
D 4 132 MET 132 132 132 MET MET B . n 
D 4 133 GLY 133 133 133 GLY GLY B . n 
D 4 134 CYS 134 134 134 CYS CYS B . n 
D 4 135 SER 135 135 135 SER SER B . n 
D 4 136 ASN 136 136 136 ASN ASN B . n 
D 4 137 LEU 137 137 137 LEU LEU B . n 
D 4 138 ASN 138 138 138 ASN ASN B . n 
D 4 139 ASN 139 139 139 ASN ASN B . n 
D 4 140 THR 140 140 140 THR THR B . n 
D 4 141 PRO 141 141 141 PRO PRO B . n 
D 4 142 GLU 142 142 142 GLU GLU B . n 
D 4 143 PHE 143 143 143 PHE PHE B . n 
D 4 144 SER 144 144 144 SER SER B . n 
D 4 145 GLU 145 145 145 GLU GLU B . n 
D 4 146 LEU 146 146 146 LEU LEU B . n 
D 4 147 SER 147 147 147 SER SER B . n 
D 4 148 GLY 148 148 148 GLY GLY B . n 
D 4 149 GLY 149 149 149 GLY GLY B . n 
D 4 150 ASP 150 150 150 ASP ASP B . n 
D 4 151 SER 151 151 151 SER SER B . n 
D 4 152 ALA 152 152 152 ALA ALA B . n 
D 4 153 ARG 153 153 153 ARG ARG B . n 
D 4 154 MET 154 154 154 MET MET B . n 
D 4 155 PHE 155 155 155 PHE PHE B . n 
D 4 156 THR 156 156 156 THR THR B . n 
D 4 157 ASP 157 157 157 ASP ASP B . n 
D 4 158 THR 158 158 158 THR THR B . n 
D 4 159 GLN 159 159 159 GLN GLN B . n 
D 4 160 VAL 160 160 160 VAL VAL B . n 
D 4 161 GLY 161 161 161 GLY GLY B . n 
D 4 162 GLU 162 162 162 GLU GLU B . n 
D 4 163 SER 163 163 163 SER SER B . n 
D 4 164 ASN 164 164 164 ASN ASN B . n 
D 4 165 ALA 165 165 165 ALA ALA B . n 
D 4 166 LYS 166 166 166 LYS LYS B . n 
D 4 167 LYS 167 167 167 LYS LYS B . n 
D 4 168 VAL 168 168 168 VAL VAL B . n 
D 4 169 GLN 169 169 169 GLN GLN B . n 
D 4 170 THR 170 170 170 THR THR B . n 
D 4 171 ALA 171 171 171 ALA ALA B . n 
D 4 172 VAL 172 172 172 VAL VAL B . n 
D 4 173 TRP 173 173 173 TRP TRP B . n 
D 4 174 ASN 174 174 174 ASN ASN B . n 
D 4 175 ALA 175 175 175 ALA ALA B . n 
D 4 176 GLY 176 176 176 GLY GLY B . n 
D 4 177 MET 177 177 177 MET MET B . n 
D 4 178 GLY 178 178 178 GLY GLY B . n 
D 4 179 VAL 179 179 179 VAL VAL B . n 
D 4 180 GLY 180 180 180 GLY GLY B . n 
D 4 181 VAL 181 181 181 VAL VAL B . n 
D 4 182 GLY 182 182 182 GLY GLY B . n 
D 4 183 ASN 183 183 183 ASN ASN B . n 
D 4 184 LEU 184 184 184 LEU LEU B . n 
D 4 185 THR 185 185 185 THR THR B . n 
D 4 186 ILE 186 186 186 ILE ILE B . n 
D 4 187 PHE 187 187 187 PHE PHE B . n 
D 4 188 PRO 188 188 188 PRO PRO B . n 
D 4 189 HIS 189 189 189 HIS HIS B . n 
D 4 190 GLN 190 190 190 GLN GLN B . n 
D 4 191 TRP 191 191 191 TRP TRP B . n 
D 4 192 ILE 192 192 192 ILE ILE B . n 
D 4 193 ASN 193 193 193 ASN ASN B . n 
D 4 194 LEU 194 194 194 LEU LEU B . n 
D 4 195 ARG 195 195 195 ARG ARG B . n 
D 4 196 THR 196 196 196 THR THR B . n 
D 4 197 ASN 197 197 197 ASN ASN B . n 
D 4 198 ASN 198 198 198 ASN ASN B . n 
D 4 199 SER 199 199 199 SER SER B . n 
D 4 200 ALA 200 200 200 ALA ALA B . n 
D 4 201 THR 201 201 201 THR THR B . n 
D 4 202 LEU 202 202 202 LEU LEU B . n 
D 4 203 VAL 203 203 203 VAL VAL B . n 
D 4 204 MET 204 204 204 MET MET B . n 
D 4 205 PRO 205 205 205 PRO PRO B . n 
D 4 206 TYR 206 206 206 TYR TYR B . n 
D 4 207 ILE 207 207 207 ILE ILE B . n 
D 4 208 ASN 208 208 208 ASN ASN B . n 
D 4 209 SER 209 209 209 SER SER B . n 
D 4 210 VAL 210 210 210 VAL VAL B . n 
D 4 211 PRO 211 211 211 PRO PRO B . n 
D 4 212 MET 212 212 212 MET MET B . n 
D 4 213 ASP 213 213 213 ASP ASP B . n 
D 4 214 ASN 214 214 214 ASN ASN B . n 
D 4 215 MET 215 215 215 MET MET B . n 
D 4 216 PHE 216 216 216 PHE PHE B . n 
D 4 217 ARG 217 217 217 ARG ARG B . n 
D 4 218 HIS 218 218 218 HIS HIS B . n 
D 4 219 ASN 219 219 219 ASN ASN B . n 
D 4 220 ASN 220 220 220 ASN ASN B . n 
D 4 221 LEU 221 221 221 LEU LEU B . n 
D 4 222 THR 222 222 222 THR THR B . n 
D 4 223 LEU 223 223 223 LEU LEU B . n 
D 4 224 MET 224 224 224 MET MET B . n 
D 4 225 ILE 225 225 225 ILE ILE B . n 
D 4 226 ILE 226 226 226 ILE ILE B . n 
D 4 227 PRO 227 227 227 PRO PRO B . n 
D 4 228 PHE 228 228 228 PHE PHE B . n 
D 4 229 VAL 229 229 229 VAL VAL B . n 
D 4 230 PRO 230 230 230 PRO PRO B . n 
D 4 231 LEU 231 231 231 LEU LEU B . n 
D 4 232 ASN 232 232 232 ASN ASN B . n 
D 4 233 TYR 233 233 233 TYR TYR B . n 
D 4 234 SER 234 234 234 SER SER B . n 
D 4 235 GLU 235 235 235 GLU GLU B . n 
D 4 236 GLY 236 236 236 GLY GLY B . n 
D 4 237 SER 237 237 237 SER SER B . n 
D 4 238 SER 238 238 238 SER SER B . n 
D 4 239 PRO 239 239 239 PRO PRO B . n 
D 4 240 TYR 240 240 240 TYR TYR B . n 
D 4 241 VAL 241 241 241 VAL VAL B . n 
D 4 242 PRO 242 242 242 PRO PRO B . n 
D 4 243 ILE 243 243 243 ILE ILE B . n 
D 4 244 THR 244 244 244 THR THR B . n 
D 4 245 VAL 245 245 245 VAL VAL B . n 
D 4 246 THR 246 246 246 THR THR B . n 
D 4 247 ILE 247 247 247 ILE ILE B . n 
D 4 248 ALA 248 248 248 ALA ALA B . n 
D 4 249 PRO 249 249 249 PRO PRO B . n 
D 4 250 MET 250 250 250 MET MET B . n 
D 4 251 CYS 251 251 251 CYS CYS B . n 
D 4 252 ALA 252 252 252 ALA ALA B . n 
D 4 253 GLU 253 253 253 GLU GLU B . n 
D 4 254 TYR 254 254 254 TYR TYR B . n 
D 4 255 ASN 255 255 255 ASN ASN B . n 
D 4 256 GLY 256 256 256 GLY GLY B . n 
D 4 257 LEU 257 257 257 LEU LEU B . n 
D 4 258 ARG 258 258 ?   ?   ?   B . n 
D 4 259 LEU 259 259 ?   ?   ?   B . n 
D 4 260 ALA 260 260 ?   ?   ?   B . n 
D 4 261 SER 261 261 ?   ?   ?   B . n 
D 4 262 ASN 262 262 ?   ?   ?   B . n 
D 4 263 GLN 263 263 ?   ?   ?   B . n 
E 5 1   GLY 1   1   1   GLY GLY C . n 
E 5 2   LEU 2   2   2   LEU LEU C . n 
E 5 3   PRO 3   3   3   PRO PRO C . n 
E 5 4   VAL 4   4   4   VAL VAL C . n 
E 5 5   MET 5   5   5   MET MET C . n 
E 5 6   THR 6   6   6   THR THR C . n 
E 5 7   THR 7   7   7   THR THR C . n 
E 5 8   PRO 8   8   8   PRO PRO C . n 
E 5 9   GLY 9   9   9   GLY GLY C . n 
E 5 10  SER 10  10  10  SER SER C . n 
E 5 11  THR 11  11  11  THR THR C . n 
E 5 12  GLN 12  12  12  GLN GLN C . n 
E 5 13  PHE 13  13  13  PHE PHE C . n 
E 5 14  LEU 14  14  14  LEU LEU C . n 
E 5 15  THR 15  15  15  THR THR C . n 
E 5 16  SER 16  16  16  SER SER C . n 
E 5 17  ASP 17  17  17  ASP ASP C . n 
E 5 18  ASP 18  18  18  ASP ASP C . n 
E 5 19  PHE 19  19  19  PHE PHE C . n 
E 5 20  GLN 20  20  20  GLN GLN C . n 
E 5 21  SER 21  21  21  SER SER C . n 
E 5 22  PRO 22  22  22  PRO PRO C . n 
E 5 23  SER 23  23  23  SER SER C . n 
E 5 24  ALA 24  24  24  ALA ALA C . n 
E 5 25  MET 25  25  25  MET MET C . n 
E 5 26  PRO 26  26  26  PRO PRO C . n 
E 5 27  GLN 27  27  27  GLN GLN C . n 
E 5 28  PHE 28  28  28  PHE PHE C . n 
E 5 29  ASP 29  29  29  ASP ASP C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  THR 31  31  31  THR THR C . n 
E 5 32  PRO 32  32  32  PRO PRO C . n 
E 5 33  GLU 33  33  33  GLU GLU C . n 
E 5 34  MET 34  34  34  MET MET C . n 
E 5 35  GLN 35  35  35  GLN GLN C . n 
E 5 36  ILE 36  36  36  ILE ILE C . n 
E 5 37  PRO 37  37  37  PRO PRO C . n 
E 5 38  GLY 38  38  38  GLY GLY C . n 
E 5 39  ARG 39  39  39  ARG ARG C . n 
E 5 40  VAL 40  40  40  VAL VAL C . n 
E 5 41  ASN 41  41  41  ASN ASN C . n 
E 5 42  ASN 42  42  42  ASN ASN C . n 
E 5 43  LEU 43  43  43  LEU LEU C . n 
E 5 44  MET 44  44  44  MET MET C . n 
E 5 45  GLU 45  45  45  GLU GLU C . n 
E 5 46  ILE 46  46  46  ILE ILE C . n 
E 5 47  ALA 47  47  47  ALA ALA C . n 
E 5 48  GLU 48  48  48  GLU GLU C . n 
E 5 49  VAL 49  49  49  VAL VAL C . n 
E 5 50  ASP 50  50  50  ASP ASP C . n 
E 5 51  SER 51  51  51  SER SER C . n 
E 5 52  VAL 52  52  52  VAL VAL C . n 
E 5 53  VAL 53  53  53  VAL VAL C . n 
E 5 54  PRO 54  54  54  PRO PRO C . n 
E 5 55  VAL 55  55  55  VAL VAL C . n 
E 5 56  ASN 56  56  56  ASN ASN C . n 
E 5 57  ASN 57  57  57  ASN ASN C . n 
E 5 58  THR 58  58  58  THR THR C . n 
E 5 59  GLU 59  59  59  GLU GLU C . n 
E 5 60  ASP 60  60  60  ASP ASP C . n 
E 5 61  ASN 61  61  61  ASN ASN C . n 
E 5 62  VAL 62  62  62  VAL VAL C . n 
E 5 63  SER 63  63  63  SER SER C . n 
E 5 64  SER 64  64  64  SER SER C . n 
E 5 65  LEU 65  65  65  LEU LEU C . n 
E 5 66  LYS 66  66  66  LYS LYS C . n 
E 5 67  ALA 67  67  67  ALA ALA C . n 
E 5 68  TYR 68  68  68  TYR TYR C . n 
E 5 69  GLN 69  69  69  GLN GLN C . n 
E 5 70  ILE 70  70  70  ILE ILE C . n 
E 5 71  PRO 71  71  71  PRO PRO C . n 
E 5 72  VAL 72  72  72  VAL VAL C . n 
E 5 73  GLN 73  73  73  GLN GLN C . n 
E 5 74  SER 74  74  74  SER SER C . n 
E 5 75  ASN 75  75  75  ASN ASN C . n 
E 5 76  SER 76  76  76  SER SER C . n 
E 5 77  ASP 77  77  77  ASP ASP C . n 
E 5 78  ASN 78  78  78  ASN ASN C . n 
E 5 79  GLY 79  79  79  GLY GLY C . n 
E 5 80  LYS 80  80  80  LYS LYS C . n 
E 5 81  GLN 81  81  81  GLN GLN C . n 
E 5 82  VAL 82  82  82  VAL VAL C . n 
E 5 83  PHE 83  83  83  PHE PHE C . n 
E 5 84  GLY 84  84  84  GLY GLY C . n 
E 5 85  PHE 85  85  85  PHE PHE C . n 
E 5 86  PRO 86  86  86  PRO PRO C . n 
E 5 87  LEU 87  87  87  LEU LEU C . n 
E 5 88  GLN 88  88  88  GLN GLN C . n 
E 5 89  PRO 89  89  89  PRO PRO C . n 
E 5 90  GLY 90  90  90  GLY GLY C . n 
E 5 91  ALA 91  91  91  ALA ALA C . n 
E 5 92  ASN 92  92  92  ASN ASN C . n 
E 5 93  ASN 93  93  93  ASN ASN C . n 
E 5 94  VAL 94  94  94  VAL VAL C . n 
E 5 95  LEU 95  95  95  LEU LEU C . n 
E 5 96  ASN 96  96  96  ASN ASN C . n 
E 5 97  ARG 97  97  97  ARG ARG C . n 
E 5 98  THR 98  98  98  THR THR C . n 
E 5 99  LEU 99  99  99  LEU LEU C . n 
E 5 100 LEU 100 100 100 LEU LEU C . n 
E 5 101 GLY 101 101 101 GLY GLY C . n 
E 5 102 GLU 102 102 102 GLU GLU C . n 
E 5 103 ILE 103 103 103 ILE ILE C . n 
E 5 104 LEU 104 104 104 LEU LEU C . n 
E 5 105 ASN 105 105 105 ASN ASN C . n 
E 5 106 TYR 106 106 106 TYR TYR C . n 
E 5 107 TYR 107 107 107 TYR TYR C . n 
E 5 108 THR 108 108 108 THR THR C . n 
E 5 109 HIS 109 109 109 HIS HIS C . n 
E 5 110 TRP 110 110 110 TRP TRP C . n 
E 5 111 SER 111 111 111 SER SER C . n 
E 5 112 GLY 112 112 112 GLY GLY C . n 
E 5 113 SER 113 113 113 SER SER C . n 
E 5 114 ILE 114 114 114 ILE ILE C . n 
E 5 115 LYS 115 115 115 LYS LYS C . n 
E 5 116 LEU 116 116 116 LEU LEU C . n 
E 5 117 THR 117 117 117 THR THR C . n 
E 5 118 PHE 118 118 118 PHE PHE C . n 
E 5 119 MET 119 119 119 MET MET C . n 
E 5 120 PHE 120 120 120 PHE PHE C . n 
E 5 121 CYS 121 121 121 CYS CYS C . n 
E 5 122 GLY 122 122 122 GLY GLY C . n 
E 5 123 SER 123 123 123 SER SER C . n 
E 5 124 ALA 124 124 124 ALA ALA C . n 
E 5 125 MET 125 125 125 MET MET C . n 
E 5 126 ALA 126 126 126 ALA ALA C . n 
E 5 127 THR 127 127 127 THR THR C . n 
E 5 128 GLY 128 128 128 GLY GLY C . n 
E 5 129 LYS 129 129 129 LYS LYS C . n 
E 5 130 PHE 130 130 130 PHE PHE C . n 
E 5 131 LEU 131 131 131 LEU LEU C . n 
E 5 132 LEU 132 132 132 LEU LEU C . n 
E 5 133 ALA 133 133 133 ALA ALA C . n 
E 5 134 TYR 134 134 134 TYR TYR C . n 
E 5 135 SER 135 135 135 SER SER C . n 
E 5 136 PRO 136 136 136 PRO PRO C . n 
E 5 137 PRO 137 137 137 PRO PRO C . n 
E 5 138 GLY 138 138 138 GLY GLY C . n 
E 5 139 ALA 139 139 139 ALA ALA C . n 
E 5 140 GLY 140 140 140 GLY GLY C . n 
E 5 141 VAL 141 141 141 VAL VAL C . n 
E 5 142 PRO 142 142 142 PRO PRO C . n 
E 5 143 LYS 143 143 143 LYS LYS C . n 
E 5 144 ASN 144 144 144 ASN ASN C . n 
E 5 145 ARG 145 145 145 ARG ARG C . n 
E 5 146 LYS 146 146 146 LYS LYS C . n 
E 5 147 ASP 147 147 147 ASP ASP C . n 
E 5 148 ALA 148 148 148 ALA ALA C . n 
E 5 149 MET 149 149 149 MET MET C . n 
E 5 150 LEU 150 150 150 LEU LEU C . n 
E 5 151 GLY 151 151 151 GLY GLY C . n 
E 5 152 THR 152 152 152 THR THR C . n 
E 5 153 HIS 153 153 153 HIS HIS C . n 
E 5 154 VAL 154 154 154 VAL VAL C . n 
E 5 155 ILE 155 155 155 ILE ILE C . n 
E 5 156 TRP 156 156 156 TRP TRP C . n 
E 5 157 ASP 157 157 157 ASP ASP C . n 
E 5 158 VAL 158 158 158 VAL VAL C . n 
E 5 159 GLY 159 159 159 GLY GLY C . n 
E 5 160 LEU 160 160 160 LEU LEU C . n 
E 5 161 GLN 161 161 161 GLN GLN C . n 
E 5 162 SER 162 162 162 SER SER C . n 
E 5 163 SER 163 163 163 SER SER C . n 
E 5 164 CYS 164 164 164 CYS CYS C . n 
E 5 165 VAL 165 165 165 VAL VAL C . n 
E 5 166 LEU 166 166 166 LEU LEU C . n 
E 5 167 CYS 167 167 167 CYS CYS C . n 
E 5 168 VAL 168 168 168 VAL VAL C . n 
E 5 169 PRO 169 169 169 PRO PRO C . n 
E 5 170 TRP 170 170 170 TRP TRP C . n 
E 5 171 ILE 171 171 171 ILE ILE C . n 
E 5 172 SER 172 172 172 SER SER C . n 
E 5 173 GLN 173 173 ?   ?   ?   C . n 
E 5 174 THR 174 174 ?   ?   ?   C . n 
E 5 175 HIS 175 175 ?   ?   ?   C . n 
E 5 176 TYR 176 176 ?   ?   ?   C . n 
E 5 177 ARG 177 177 ?   ?   ?   C . n 
E 5 178 TYR 178 178 ?   ?   ?   C . n 
E 5 179 VAL 179 179 ?   ?   ?   C . n 
E 5 180 VAL 180 180 ?   ?   ?   C . n 
E 5 181 GLU 181 181 ?   ?   ?   C . n 
E 5 182 ASP 182 182 ?   ?   ?   C . n 
E 5 183 GLU 183 183 ?   ?   ?   C . n 
E 5 184 TYR 184 184 ?   ?   ?   C . n 
E 5 185 THR 185 185 ?   ?   ?   C . n 
E 5 186 ALA 186 186 186 ALA ALA C . n 
E 5 187 ALA 187 187 187 ALA ALA C . n 
E 5 188 GLY 188 188 188 GLY GLY C . n 
E 5 189 TYR 189 189 189 TYR TYR C . n 
E 5 190 VAL 190 190 190 VAL VAL C . n 
E 5 191 THR 191 191 191 THR THR C . n 
E 5 192 CYS 192 192 192 CYS CYS C . n 
E 5 193 TRP 193 193 193 TRP TRP C . n 
E 5 194 TYR 194 194 194 TYR TYR C . n 
E 5 195 GLN 195 195 195 GLN GLN C . n 
E 5 196 THR 196 196 196 THR THR C . n 
E 5 197 ASN 197 197 197 ASN ASN C . n 
E 5 198 ILE 198 198 198 ILE ILE C . n 
E 5 199 VAL 199 199 199 VAL VAL C . n 
E 5 200 VAL 200 200 200 VAL VAL C . n 
E 5 201 PRO 201 201 201 PRO PRO C . n 
E 5 202 ALA 202 202 202 ALA ALA C . n 
E 5 203 ASP 203 203 203 ASP ASP C . n 
E 5 204 VAL 204 204 204 VAL VAL C . n 
E 5 205 GLN 205 205 205 GLN GLN C . n 
E 5 206 SER 206 206 206 SER SER C . n 
E 5 207 SER 207 207 207 SER SER C . n 
E 5 208 CYS 208 208 208 CYS CYS C . n 
E 5 209 ASP 209 209 209 ASP ASP C . n 
E 5 210 ILE 210 210 210 ILE ILE C . n 
E 5 211 LEU 211 211 211 LEU LEU C . n 
E 5 212 CYS 212 212 212 CYS CYS C . n 
E 5 213 PHE 213 213 213 PHE PHE C . n 
E 5 214 VAL 214 214 214 VAL VAL C . n 
E 5 215 SER 215 215 215 SER SER C . n 
E 5 216 ALA 216 216 216 ALA ALA C . n 
E 5 217 CYS 217 217 217 CYS CYS C . n 
E 5 218 ASN 218 218 218 ASN ASN C . n 
E 5 219 ASP 219 219 219 ASP ASP C . n 
E 5 220 PHE 220 220 220 PHE PHE C . n 
E 5 221 SER 221 221 221 SER SER C . n 
E 5 222 VAL 222 222 222 VAL VAL C . n 
E 5 223 ARG 223 223 223 ARG ARG C . n 
E 5 224 MET 224 224 224 MET MET C . n 
E 5 225 LEU 225 225 225 LEU LEU C . n 
E 5 226 LYS 226 226 226 LYS LYS C . n 
E 5 227 ASP 227 227 227 ASP ASP C . n 
E 5 228 THR 228 228 228 THR THR C . n 
E 5 229 PRO 229 229 229 PRO PRO C . n 
E 5 230 PHE 230 230 230 PHE PHE C . n 
E 5 231 ILE 231 231 231 ILE ILE C . n 
E 5 232 ARG 232 232 232 ARG ARG C . n 
E 5 233 GLN 233 233 ?   ?   ?   C . n 
E 5 234 ASP 234 234 ?   ?   ?   C . n 
E 5 235 THR 235 235 ?   ?   ?   C . n 
E 5 236 PHE 236 236 ?   ?   ?   C . n 
E 5 237 TYR 237 237 ?   ?   ?   C . n 
E 5 238 GLN 238 238 ?   ?   ?   C . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              abing0811@xmu.edu.cn 
_pdbx_contact_author.name_first         Qingbing 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7516-9965 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     0.00000000  1.00000000  0.00000000  -313.60001 -1.00000000 0.00000000  0.00000000  
313.60001  0.00000000  0.00000000  1.00000000  -313.60001 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901699 507.41548  0.80901699  0.30901699  0.50000000  
-193.81547 -0.30901699 -0.50000000 0.80901699  313.60001  
3  'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 821.01549  0.50000000  -0.80901699 0.30901699  
313.60001  -0.80901699 -0.30901699 0.50000000  507.41548  
4  'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 507.41548  -0.50000000 -0.80901699 -0.30901699 
821.01549  -0.80901699 0.30901699  0.50000000  313.60001  
5  'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000    -0.80901699 0.30901699  -0.50000000 
627.20002  -0.30901699 0.50000000  0.80901699  0.00000    
6  'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  627.20002  0.00000000  -1.00000000 0.00000000  
627.20002  0.00000000  0.00000000  1.00000000  0.00000    
7  'point symmetry operation' ?     ?     -0.50000000 0.80901699  0.30901699  119.78454  -0.80901699 -0.30901699 -0.50000000 
821.01549  -0.30901699 -0.50000000 0.80901699  313.60001  
8  'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901699  -193.81547 -0.50000000 0.80901699  -0.30901699 
313.60001  -0.80901699 -0.30901699 0.50000000  507.41548  
9  'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  119.78454  0.50000000  0.80901699  0.30901699  
-193.81547 -0.80901699 0.30901699  0.50000000  313.60001  
10 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  627.20002  0.80901699  -0.30901699 0.50000000  
0.00000    -0.30901699 0.50000000  0.80901699  0.00000    
11 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
627.20002  0.00000000  0.00000000  -1.00000000 627.20002  
12 'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901699 507.41548  -0.80901699 -0.30901699 -0.50000000 
821.01549  0.30901699  0.50000000  -0.80901699 313.60001  
13 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 821.01549  -0.50000000 0.80901699  -0.30901699 
313.60001  0.80901699  0.30901699  -0.50000000 119.78454  
14 'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 507.41548  0.50000000  0.80901699  0.30901699  
-193.81547 0.80901699  -0.30901699 -0.50000000 313.60001  
15 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000    0.80901699  -0.30901699 0.50000000  
0.00000    0.30901699  -0.50000000 -0.80901699 627.20002  
16 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  627.20002  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 627.20002  
17 'point symmetry operation' ?     ?     -0.50000000 0.80901699  0.30901699  119.78454  0.80901699  0.30901699  0.50000000  
-193.81547 0.30901699  0.50000000  -0.80901699 313.60001  
18 'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901699  -193.81547 0.50000000  -0.80901699 0.30901699  
313.60001  0.80901699  0.30901699  -0.50000000 119.78454  
19 'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  119.78454  -0.50000000 -0.80901699 -0.30901699 
821.01549  0.80901699  -0.30901699 -0.50000000 313.60001  
20 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  627.20002  -0.80901699 0.30901699  -0.50000000 
627.20002  0.30901699  -0.50000000 -0.80901699 627.20002  
21 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  627.20002  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  627.20002  
22 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 821.01549  -0.30901699 -0.50000000 0.80901699  
313.60001  -0.50000000 0.80901699  0.30901699  119.78454  
23 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901699 313.60001  -0.80901699 -0.30901699 0.50000000  
507.41548  0.30901699  0.50000000  0.80901699  -193.81547 
24 'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901699  -193.81547 -0.80901699 0.30901699  0.50000000  
313.60001  0.30901699  -0.50000000 0.80901699  119.78454  
25 'point symmetry operation' ?     ?     0.80901699  -0.30901699 0.50000000  0.00000    -0.30901699 0.50000000  0.80901699  
0.00000    -0.50000000 -0.80901699 0.30901699  627.20002  
26 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
27 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  -193.81547 -0.30901699 -0.50000000 0.80901699  
313.60001  0.50000000  -0.80901699 -0.30901699 507.41548  
28 'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  313.60001  -0.80901699 -0.30901699 0.50000000  
507.41548  -0.30901699 -0.50000000 -0.80901699 821.01549  
29 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901699 821.01549  -0.80901699 0.30901699  0.50000000  
313.60001  -0.30901699 0.50000000  -0.80901699 507.41548  
30 'point symmetry operation' ?     ?     -0.80901699 0.30901699  -0.50000000 627.20002  -0.30901699 0.50000000  0.80901699  
0.00000    0.50000000  0.80901699  -0.30901699 0.00000    
31 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
627.20002  -1.00000000 0.00000000  0.00000000  627.20002  
32 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  -193.81547 0.30901699  0.50000000  -0.80901699 
313.60001  -0.50000000 0.80901699  0.30901699  119.78454  
33 'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  313.60001  0.80901699  0.30901699  -0.50000000 
119.78454  0.30901699  0.50000000  0.80901699  -193.81547 
34 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901699 821.01549  0.80901699  -0.30901699 -0.50000000 
313.60001  0.30901699  -0.50000000 0.80901699  119.78454  
35 'point symmetry operation' ?     ?     -0.80901699 0.30901699  -0.50000000 627.20002  0.30901699  -0.50000000 -0.80901699 
627.20002  -0.50000000 -0.80901699 0.30901699  627.20002  
36 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  627.20002  0.00000000  0.00000000  -1.00000000 
627.20002  1.00000000  0.00000000  0.00000000  0.00000    
37 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 821.01549  0.30901699  0.50000000  -0.80901699 
313.60001  0.50000000  -0.80901699 -0.30901699 507.41548  
38 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901699 313.60001  0.80901699  0.30901699  -0.50000000 
119.78454  -0.30901699 -0.50000000 -0.80901699 821.01549  
39 'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901699  -193.81547 0.80901699  -0.30901699 -0.50000000 
313.60001  -0.30901699 0.50000000  -0.80901699 507.41548  
40 'point symmetry operation' ?     ?     0.80901699  -0.30901699 0.50000000  0.00000    0.30901699  -0.50000000 -0.80901699 
627.20002  0.50000000  0.80901699  -0.30901699 0.00000    
41 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 627.20002  -1.00000000 0.00000000  0.00000000  
627.20002  0.00000000  1.00000000  0.00000000  0.00000    
42 'point symmetry operation' ?     ?     0.30901699  0.50000000  -0.80901699 313.60001  -0.50000000 0.80901699  0.30901699  
119.78454  0.80901699  0.30901699  0.50000000  -193.81547 
43 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 119.78454  0.30901699  0.50000000  0.80901699  
-193.81547 0.50000000  -0.80901699 0.30901699  313.60001  
44 'point symmetry operation' ?     ?     0.80901699  -0.30901699 -0.50000000 313.60001  0.30901699  -0.50000000 0.80901699  
119.78454  -0.50000000 -0.80901699 -0.30901699 821.01549  
45 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901699 627.20002  -0.50000000 -0.80901699 0.30901699  
627.20002  -0.80901699 0.30901699  -0.50000000 627.20002  
46 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 627.20002  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  627.20002  
47 'point symmetry operation' ?     ?     0.30901699  0.50000000  -0.80901699 313.60001  0.50000000  -0.80901699 -0.30901699 
507.41548  -0.80901699 -0.30901699 -0.50000000 821.01549  
48 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 119.78454  -0.30901699 -0.50000000 -0.80901699 
821.01549  -0.50000000 0.80901699  -0.30901699 313.60001  
49 'point symmetry operation' ?     ?     0.80901699  -0.30901699 -0.50000000 313.60001  -0.30901699 0.50000000  -0.80901699 
507.41548  0.50000000  0.80901699  0.30901699  -193.81547 
50 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901699 627.20002  0.50000000  0.80901699  -0.30901699 
0.00000    0.80901699  -0.30901699 0.50000000  0.00000    
51 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
627.20002  0.00000000  -1.00000000 0.00000000  627.20002  
52 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901699  313.60001  -0.50000000 0.80901699  0.30901699  
119.78454  -0.80901699 -0.30901699 -0.50000000 821.01549  
53 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 0.50000000  507.41548  0.30901699  0.50000000  0.80901699  
-193.81547 -0.50000000 0.80901699  -0.30901699 313.60001  
54 'point symmetry operation' ?     ?     -0.80901699 0.30901699  0.50000000  313.60001  0.30901699  -0.50000000 0.80901699  
119.78454  0.50000000  0.80901699  0.30901699  -193.81547 
55 'point symmetry operation' ?     ?     -0.30901699 0.50000000  0.80901699  0.00000    -0.50000000 -0.80901699 0.30901699  
627.20002  0.80901699  -0.30901699 0.50000000  0.00000    
56 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
57 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901699  313.60001  0.50000000  -0.80901699 -0.30901699 
507.41548  0.80901699  0.30901699  0.50000000  -193.81547 
58 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 0.50000000  507.41548  -0.30901699 -0.50000000 -0.80901699 
821.01549  0.50000000  -0.80901699 0.30901699  313.60001  
59 'point symmetry operation' ?     ?     -0.80901699 0.30901699  0.50000000  313.60001  -0.30901699 0.50000000  -0.80901699 
507.41548  -0.50000000 -0.80901699 -0.30901699 821.01549  
60 'point symmetry operation' ?     ?     -0.30901699 0.50000000  0.80901699  0.00000    0.50000000  0.80901699  -0.30901699 
0.00000    -0.80901699 0.30901699  -0.50000000 627.20002  
# 
_pdbx_point_symmetry.entry_id             7X3F 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2022-09-28 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.14_3259: 
_software.pdbx_ordinal           1 
# 
_em_3d_fitting.entry_id          7X3F 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7X3F 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               40586 
_em_3d_reconstruction.resolution                  3.52 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.details              ? 
_em_entity_assembly.name                 'Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 9A3 (CVB1-A:9A3)' 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7X3F 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI TECNAI F30' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             3200 
_em_imaging.nominal_defocus_min             900 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7X3F 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7X3F 
_em_experiment.id                      1 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OE1 C GLU 48 ? ? OD1 C ASN 218 ? ? 1.83 
2 1 CD  C GLU 48 ? ? OD1 C ASN 218 ? ? 2.10 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CB A TRP 245 ? ? CG  A TRP 245 ? ? 1.382 1.498 -0.116 0.018 N 
2 1 CG A TRP 245 ? ? CD1 A TRP 245 ? ? 1.273 1.363 -0.090 0.014 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 C A PRO 249 ? ? N A PRO 250 ? ? CA A PRO 250 ? ? 136.58 119.30 17.28  1.50 Y 
2 1 C A PRO 249 ? ? N A PRO 250 ? ? CD A PRO 250 ? ? 112.42 128.40 -15.98 2.10 Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR H 30  ? ? -92.31  30.97   
2  1 TYR H 110 ? ? -95.50  35.51   
3  1 THR L 52  ? ? 64.17   -8.65   
4  1 LYS A 84  ? ? 58.17   4.98    
5  1 LYS A 85  ? ? -141.17 33.07   
6  1 ARG A 95  ? ? -94.26  34.08   
7  1 ALA A 129 ? ? -172.19 -174.40 
8  1 SER A 130 ? ? 63.70   63.08   
9  1 SER A 131 ? ? 60.05   66.02   
10 1 ASN A 208 ? ? 58.00   74.27   
11 1 THR A 209 ? ? -66.43  5.60    
12 1 VAL A 246 ? ? 47.53   80.09   
13 1 ASN B 74  ? ? -93.73  48.22   
14 1 PRO B 83  ? ? -87.16  42.95   
15 1 ASP B 150 ? ? 39.29   42.88   
16 1 SER C 10  ? ? -96.78  -62.92  
17 1 THR C 11  ? ? -98.25  57.93   
18 1 THR C 58  ? ? 34.66   36.45   
19 1 GLU C 59  ? ? 70.86   -10.98  
20 1 SER C 63  ? ? -96.72  51.71   
21 1 ASN C 92  ? ? 48.62   22.41   
22 1 GLN C 195 ? ? -91.75  -60.51  
23 1 ASN C 218 ? ? 82.04   4.27    
24 1 MET C 224 ? ? 61.07   73.42   
25 1 PHE C 230 ? ? -92.74  53.88   
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     L 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     ALA 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      101 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     CB 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    B 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    ALA 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     101 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    CB 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 L GLU 1   ? B GLU 1   
2   1 Y 1 A GLY 1   ? C GLY 1   
3   1 Y 1 A PRO 2   ? C PRO 2   
4   1 Y 1 A VAL 3   ? C VAL 3   
5   1 Y 1 A GLU 4   ? C GLU 4   
6   1 Y 1 A GLU 5   ? C GLU 5   
7   1 Y 1 A SER 6   ? C SER 6   
8   1 Y 1 A VAL 7   ? C VAL 7   
9   1 Y 1 A ASP 8   ? C ASP 8   
10  1 Y 1 A ARG 9   ? C ARG 9   
11  1 Y 1 A ALA 10  ? C ALA 10  
12  1 Y 1 A VAL 11  ? C VAL 11  
13  1 Y 1 A ALA 12  ? C ALA 12  
14  1 Y 1 A ARG 13  ? C ARG 13  
15  1 Y 1 A VAL 14  ? C VAL 14  
16  1 Y 1 A ALA 15  ? C ALA 15  
17  1 Y 1 A ASP 16  ? C ASP 16  
18  1 Y 1 A THR 17  ? C THR 17  
19  1 Y 1 A ILE 18  ? C ILE 18  
20  1 Y 1 A SER 19  ? C SER 19  
21  1 Y 1 A SER 20  ? C SER 20  
22  1 Y 1 A ARG 21  ? C ARG 21  
23  1 Y 1 A PRO 22  ? C PRO 22  
24  1 Y 1 A THR 23  ? C THR 23  
25  1 Y 1 A ASN 24  ? C ASN 24  
26  1 Y 1 A SER 25  ? C SER 25  
27  1 Y 1 A GLU 26  ? C GLU 26  
28  1 Y 1 A SER 27  ? C SER 27  
29  1 Y 1 A ILE 28  ? C ILE 28  
30  1 Y 1 A PRO 29  ? C PRO 29  
31  1 Y 1 A ALA 30  ? C ALA 30  
32  1 Y 1 A LEU 31  ? C LEU 31  
33  1 Y 1 A THR 32  ? C THR 32  
34  1 Y 1 A ALA 33  ? C ALA 33  
35  1 Y 1 A ALA 34  ? C ALA 34  
36  1 Y 1 A GLU 35  ? C GLU 35  
37  1 Y 1 A THR 36  ? C THR 36  
38  1 Y 1 A GLY 37  ? C GLY 37  
39  1 Y 1 A HIS 38  ? C HIS 38  
40  1 Y 1 A THR 39  ? C THR 39  
41  1 Y 1 A SER 40  ? C SER 40  
42  1 Y 1 A GLN 41  ? C GLN 41  
43  1 Y 1 A VAL 42  ? C VAL 42  
44  1 Y 1 A VAL 43  ? C VAL 43  
45  1 Y 1 A PRO 44  ? C PRO 44  
46  1 Y 1 A SER 45  ? C SER 45  
47  1 Y 1 A ASP 46  ? C ASP 46  
48  1 Y 1 A THR 47  ? C THR 47  
49  1 Y 1 A MET 48  ? C MET 48  
50  1 Y 1 A GLN 49  ? C GLN 49  
51  1 Y 1 A THR 50  ? C THR 50  
52  1 Y 1 A ARG 51  ? C ARG 51  
53  1 Y 1 A HIS 52  ? C HIS 52  
54  1 Y 1 A VAL 53  ? C VAL 53  
55  1 Y 1 A LYS 54  ? C LYS 54  
56  1 Y 1 A ASN 55  ? C ASN 55  
57  1 Y 1 A TYR 56  ? C TYR 56  
58  1 Y 1 A HIS 57  ? C HIS 57  
59  1 Y 1 A GLN 198 ? C GLN 198 
60  1 Y 1 A PHE 199 ? C PHE 199 
61  1 Y 1 A SER 200 ? C SER 200 
62  1 Y 1 A ARG 201 ? C ARG 201 
63  1 Y 1 A ASN 202 ? C ASN 202 
64  1 Y 1 A GLY 203 ? C GLY 203 
65  1 Y 1 A THR 277 ? C THR 277 
66  1 Y 1 A THR 278 ? C THR 278 
67  1 Y 1 B SER 1   ? D SER 1   
68  1 Y 1 B PRO 2   ? D PRO 2   
69  1 Y 1 B SER 3   ? D SER 3   
70  1 Y 1 B ALA 4   ? D ALA 4   
71  1 Y 1 B GLU 5   ? D GLU 5   
72  1 Y 1 B GLU 6   ? D GLU 6   
73  1 Y 1 B CYS 7   ? D CYS 7   
74  1 Y 1 B GLY 8   ? D GLY 8   
75  1 Y 1 B TYR 9   ? D TYR 9   
76  1 Y 1 B SER 10  ? D SER 10  
77  1 Y 1 B ASP 11  ? D ASP 11  
78  1 Y 1 B ARG 12  ? D ARG 12  
79  1 Y 1 B VAL 13  ? D VAL 13  
80  1 Y 1 B GLU 27  ? D GLU 27  
81  1 Y 1 B CYS 28  ? D CYS 28  
82  1 Y 1 B ALA 29  ? D ALA 29  
83  1 Y 1 B LYS 43  ? D LYS 43  
84  1 Y 1 B ASP 44  ? D ASP 44  
85  1 Y 1 B ASN 45  ? D ASN 45  
86  1 Y 1 B GLU 46  ? D GLU 46  
87  1 Y 1 B ALA 47  ? D ALA 47  
88  1 Y 1 B THR 48  ? D THR 48  
89  1 Y 1 B ALA 49  ? D ALA 49  
90  1 Y 1 B GLU 50  ? D GLU 50  
91  1 Y 1 B ARG 258 ? D ARG 258 
92  1 Y 1 B LEU 259 ? D LEU 259 
93  1 Y 1 B ALA 260 ? D ALA 260 
94  1 Y 1 B SER 261 ? D SER 261 
95  1 Y 1 B ASN 262 ? D ASN 262 
96  1 Y 1 B GLN 263 ? D GLN 263 
97  1 Y 1 C GLN 173 ? E GLN 173 
98  1 Y 1 C THR 174 ? E THR 174 
99  1 Y 1 C HIS 175 ? E HIS 175 
100 1 Y 1 C TYR 176 ? E TYR 176 
101 1 Y 1 C ARG 177 ? E ARG 177 
102 1 Y 1 C TYR 178 ? E TYR 178 
103 1 Y 1 C VAL 179 ? E VAL 179 
104 1 Y 1 C VAL 180 ? E VAL 180 
105 1 Y 1 C GLU 181 ? E GLU 181 
106 1 Y 1 C ASP 182 ? E ASP 182 
107 1 Y 1 C GLU 183 ? E GLU 183 
108 1 Y 1 C TYR 184 ? E TYR 184 
109 1 Y 1 C THR 185 ? E THR 185 
110 1 Y 1 C GLN 233 ? E GLN 233 
111 1 Y 1 C ASP 234 ? E ASP 234 
112 1 Y 1 C THR 235 ? E THR 235 
113 1 Y 1 C PHE 236 ? E PHE 236 
114 1 Y 1 C TYR 237 ? E TYR 237 
115 1 Y 1 C GLN 238 ? E GLN 238 
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.ncbi_tax_id          12071 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organism             'Coxsackievirus B1' 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.ncbi_tax_id          10029 
_em_entity_assembly_recombinant.organism             'Cricetulus griseus' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       INTEGRATING 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'PARTICLE SELECTION'       ? ? ? 1 ? ? 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
