data_7X3Y
# 
_entry.id   7X3Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.370 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7X3Y         pdb_00007x3y 10.2210/pdb7x3y/pdb 
WWPDB D_1300027917 ?            ?                   
EMDB  EMD-32997    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)' 
_pdbx_database_related.db_id          EMD-32997 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7X3Y 
_pdbx_database_status.recvd_initial_deposition_date   2022-03-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zheng, Q.' 1 ? 
'Zhu, R.'   2 ? 
'Sun, H.'   3 ? 
'Cheng, T.' 4 ? 
'Li, S.'    5 ? 
'Xia, N.'   6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zheng, Q.' 1 ? 
primary 'Zhu, R.'   2 ? 
primary 'Sun, H.'   3 ? 
primary 'Cheng, T.' 4 ? 
primary 'Li, S.'    5 ? 
primary 'Xia, N.'   6 ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7X3Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         7X3Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer nat '9A3 heavy chain'  13768.251 1 ?                                     ? ? ? 
2 polymer nat '9A3 light chain'  11472.680 1 ?                                     ? ? ? 
3 polymer nat 'Virion protein 1' 31207.117 1 ?                                     ? ? ? 
4 polymer nat VP2                29122.744 1 ?                                     ? ? ? 
5 polymer nat VP3                26328.764 1 3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48 ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'VP1, P1C,P1D' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVKLVESGGGLVQPGGSLSLSCAASGFTFTDYYMNWVRQPSGKALEWLGFLRNKANGYTTEYSASVKGRFTISRDNSQSI
LYLQMNALRAEDSATYYCARSRYYGGTYRYALDYWGQGTSVTVS
;
;EVKLVESGGGLVQPGGSLSLSCAASGFTFTDYYMNWVRQPSGKALEWLGFLRNKANGYTTEYSASVKGRFTISRDNSQSI
LYLQMNALRAEDSATYYCARSRYYGGTYRYALDYWGQGTSVTVS
;
H ? 
2 'polypeptide(L)' no no 
;ENVLTQSPPIMSASPGEKVTMTCRASSSVSSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGAGTKLELK
;
;ENVLTQSPPIMSASPGEKVTMTCRASSSVSSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGAGTKLELK
;
L ? 
3 'polypeptide(L)' no no 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
A ? 
4 'polypeptide(L)' no no 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
B ? 
5 'polypeptide(L)' no no 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   LYS n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  SER n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  ALA n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  THR n 
1 29  PHE n 
1 30  THR n 
1 31  ASP n 
1 32  TYR n 
1 33  TYR n 
1 34  MET n 
1 35  ASN n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  PRO n 
1 41  SER n 
1 42  GLY n 
1 43  LYS n 
1 44  ALA n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  LEU n 
1 49  GLY n 
1 50  PHE n 
1 51  LEU n 
1 52  ARG n 
1 53  ASN n 
1 54  LYS n 
1 55  ALA n 
1 56  ASN n 
1 57  GLY n 
1 58  TYR n 
1 59  THR n 
1 60  THR n 
1 61  GLU n 
1 62  TYR n 
1 63  SER n 
1 64  ALA n 
1 65  SER n 
1 66  VAL n 
1 67  LYS n 
1 68  GLY n 
1 69  ARG n 
1 70  PHE n 
1 71  THR n 
1 72  ILE n 
1 73  SER n 
1 74  ARG n 
1 75  ASP n 
1 76  ASN n 
1 77  SER n 
1 78  GLN n 
1 79  SER n 
1 80  ILE n 
1 81  LEU n 
1 82  TYR n 
1 83  LEU n 
1 84  GLN n 
1 85  MET n 
1 86  ASN n 
1 87  ALA n 
1 88  LEU n 
1 89  ARG n 
1 90  ALA n 
1 91  GLU n 
1 92  ASP n 
1 93  SER n 
1 94  ALA n 
1 95  THR n 
1 96  TYR n 
1 97  TYR n 
1 98  CYS n 
1 99  ALA n 
1 100 ARG n 
1 101 SER n 
1 102 ARG n 
1 103 TYR n 
1 104 TYR n 
1 105 GLY n 
1 106 GLY n 
1 107 THR n 
1 108 TYR n 
1 109 ARG n 
1 110 TYR n 
1 111 ALA n 
1 112 LEU n 
1 113 ASP n 
1 114 TYR n 
1 115 TRP n 
1 116 GLY n 
1 117 GLN n 
1 118 GLY n 
1 119 THR n 
1 120 SER n 
1 121 VAL n 
1 122 THR n 
1 123 VAL n 
1 124 SER n 
2 1   GLU n 
2 2   ASN n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   PRO n 
2 10  ILE n 
2 11  MET n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  PRO n 
2 16  GLY n 
2 17  GLU n 
2 18  LYS n 
2 19  VAL n 
2 20  THR n 
2 21  MET n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  SER n 
2 28  SER n 
2 29  VAL n 
2 30  SER n 
2 31  SER n 
2 32  SER n 
2 33  TYR n 
2 34  LEU n 
2 35  HIS n 
2 36  TRP n 
2 37  TYR n 
2 38  GLN n 
2 39  GLN n 
2 40  LYS n 
2 41  SER n 
2 42  GLY n 
2 43  ALA n 
2 44  SER n 
2 45  PRO n 
2 46  LYS n 
2 47  LEU n 
2 48  TRP n 
2 49  ILE n 
2 50  TYR n 
2 51  SER n 
2 52  THR n 
2 53  SER n 
2 54  ASN n 
2 55  LEU n 
2 56  ALA n 
2 57  SER n 
2 58  GLY n 
2 59  VAL n 
2 60  PRO n 
2 61  ALA n 
2 62  ARG n 
2 63  PHE n 
2 64  SER n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  SER n 
2 69  GLY n 
2 70  THR n 
2 71  SER n 
2 72  TYR n 
2 73  SER n 
2 74  LEU n 
2 75  THR n 
2 76  ILE n 
2 77  SER n 
2 78  SER n 
2 79  VAL n 
2 80  GLU n 
2 81  ALA n 
2 82  GLU n 
2 83  ASP n 
2 84  ALA n 
2 85  ALA n 
2 86  THR n 
2 87  TYR n 
2 88  TYR n 
2 89  CYS n 
2 90  GLN n 
2 91  GLN n 
2 92  PHE n 
2 93  SER n 
2 94  GLY n 
2 95  TYR n 
2 96  PRO n 
2 97  LEU n 
2 98  THR n 
2 99  PHE n 
2 100 GLY n 
2 101 ALA n 
2 102 GLY n 
2 103 THR n 
2 104 LYS n 
2 105 LEU n 
2 106 GLU n 
2 107 LEU n 
2 108 LYS n 
3 1   GLY n 
3 2   PRO n 
3 3   VAL n 
3 4   GLU n 
3 5   GLU n 
3 6   SER n 
3 7   VAL n 
3 8   ASP n 
3 9   ARG n 
3 10  ALA n 
3 11  VAL n 
3 12  ALA n 
3 13  ARG n 
3 14  VAL n 
3 15  ALA n 
3 16  ASP n 
3 17  THR n 
3 18  ILE n 
3 19  SER n 
3 20  SER n 
3 21  ARG n 
3 22  PRO n 
3 23  THR n 
3 24  ASN n 
3 25  SER n 
3 26  GLU n 
3 27  SER n 
3 28  ILE n 
3 29  PRO n 
3 30  ALA n 
3 31  LEU n 
3 32  THR n 
3 33  ALA n 
3 34  ALA n 
3 35  GLU n 
3 36  THR n 
3 37  GLY n 
3 38  HIS n 
3 39  THR n 
3 40  SER n 
3 41  GLN n 
3 42  VAL n 
3 43  VAL n 
3 44  PRO n 
3 45  SER n 
3 46  ASP n 
3 47  THR n 
3 48  MET n 
3 49  GLN n 
3 50  THR n 
3 51  ARG n 
3 52  HIS n 
3 53  VAL n 
3 54  LYS n 
3 55  ASN n 
3 56  TYR n 
3 57  HIS n 
3 58  SER n 
3 59  ARG n 
3 60  SER n 
3 61  GLU n 
3 62  SER n 
3 63  SER n 
3 64  ILE n 
3 65  GLU n 
3 66  ASN n 
3 67  PHE n 
3 68  LEU n 
3 69  CYS n 
3 70  ARG n 
3 71  SER n 
3 72  ALA n 
3 73  CYS n 
3 74  VAL n 
3 75  TYR n 
3 76  TYR n 
3 77  ALA n 
3 78  THR n 
3 79  TYR n 
3 80  THR n 
3 81  ASN n 
3 82  ASN n 
3 83  SER n 
3 84  LYS n 
3 85  LYS n 
3 86  GLY n 
3 87  PHE n 
3 88  ALA n 
3 89  GLU n 
3 90  TRP n 
3 91  VAL n 
3 92  ILE n 
3 93  ASN n 
3 94  THR n 
3 95  ARG n 
3 96  GLN n 
3 97  VAL n 
3 98  ALA n 
3 99  GLN n 
3 100 LEU n 
3 101 ARG n 
3 102 ARG n 
3 103 LYS n 
3 104 LEU n 
3 105 GLU n 
3 106 LEU n 
3 107 PHE n 
3 108 THR n 
3 109 TYR n 
3 110 LEU n 
3 111 ARG n 
3 112 PHE n 
3 113 ASP n 
3 114 LEU n 
3 115 GLU n 
3 116 LEU n 
3 117 THR n 
3 118 PHE n 
3 119 VAL n 
3 120 ILE n 
3 121 THR n 
3 122 SER n 
3 123 ALA n 
3 124 GLN n 
3 125 GLN n 
3 126 PRO n 
3 127 SER n 
3 128 THR n 
3 129 ALA n 
3 130 SER n 
3 131 SER n 
3 132 VAL n 
3 133 ASP n 
3 134 ALA n 
3 135 PRO n 
3 136 VAL n 
3 137 GLN n 
3 138 THR n 
3 139 HIS n 
3 140 GLN n 
3 141 ILE n 
3 142 MET n 
3 143 TYR n 
3 144 VAL n 
3 145 PRO n 
3 146 PRO n 
3 147 GLY n 
3 148 GLY n 
3 149 PRO n 
3 150 VAL n 
3 151 PRO n 
3 152 THR n 
3 153 LYS n 
3 154 VAL n 
3 155 LYS n 
3 156 ASP n 
3 157 TYR n 
3 158 ALA n 
3 159 TRP n 
3 160 GLN n 
3 161 THR n 
3 162 SER n 
3 163 THR n 
3 164 ASN n 
3 165 PRO n 
3 166 SER n 
3 167 VAL n 
3 168 PHE n 
3 169 TRP n 
3 170 THR n 
3 171 GLU n 
3 172 GLY n 
3 173 ASN n 
3 174 ALA n 
3 175 PRO n 
3 176 PRO n 
3 177 ARG n 
3 178 MET n 
3 179 SER n 
3 180 ILE n 
3 181 PRO n 
3 182 PHE n 
3 183 ILE n 
3 184 SER n 
3 185 ILE n 
3 186 GLY n 
3 187 ASN n 
3 188 ALA n 
3 189 TYR n 
3 190 SER n 
3 191 CYS n 
3 192 PHE n 
3 193 TYR n 
3 194 ASP n 
3 195 GLY n 
3 196 TRP n 
3 197 THR n 
3 198 GLN n 
3 199 PHE n 
3 200 SER n 
3 201 ARG n 
3 202 ASN n 
3 203 GLY n 
3 204 VAL n 
3 205 TYR n 
3 206 GLY n 
3 207 ILE n 
3 208 ASN n 
3 209 THR n 
3 210 LEU n 
3 211 ASN n 
3 212 ASN n 
3 213 MET n 
3 214 GLY n 
3 215 THR n 
3 216 LEU n 
3 217 TYR n 
3 218 MET n 
3 219 ARG n 
3 220 HIS n 
3 221 VAL n 
3 222 ASN n 
3 223 GLU n 
3 224 ALA n 
3 225 GLY n 
3 226 GLN n 
3 227 GLY n 
3 228 PRO n 
3 229 ILE n 
3 230 LYS n 
3 231 SER n 
3 232 THR n 
3 233 VAL n 
3 234 ARG n 
3 235 ILE n 
3 236 TYR n 
3 237 PHE n 
3 238 LYS n 
3 239 PRO n 
3 240 LYS n 
3 241 HIS n 
3 242 VAL n 
3 243 LYS n 
3 244 ALA n 
3 245 TRP n 
3 246 VAL n 
3 247 PRO n 
3 248 ARG n 
3 249 PRO n 
3 250 PRO n 
3 251 ARG n 
3 252 LEU n 
3 253 CYS n 
3 254 GLN n 
3 255 TYR n 
3 256 GLU n 
3 257 LYS n 
3 258 GLN n 
3 259 LYS n 
3 260 ASN n 
3 261 VAL n 
3 262 ASN n 
3 263 PHE n 
3 264 SER n 
3 265 PRO n 
3 266 ILE n 
3 267 GLY n 
3 268 VAL n 
3 269 THR n 
3 270 THR n 
3 271 SER n 
3 272 ARG n 
3 273 THR n 
3 274 ASP n 
3 275 ILE n 
3 276 ILE n 
3 277 THR n 
3 278 THR n 
4 1   SER n 
4 2   PRO n 
4 3   SER n 
4 4   ALA n 
4 5   GLU n 
4 6   GLU n 
4 7   CYS n 
4 8   GLY n 
4 9   TYR n 
4 10  SER n 
4 11  ASP n 
4 12  ARG n 
4 13  VAL n 
4 14  ARG n 
4 15  SER n 
4 16  ILE n 
4 17  THR n 
4 18  LEU n 
4 19  GLY n 
4 20  ASN n 
4 21  SER n 
4 22  THR n 
4 23  ILE n 
4 24  THR n 
4 25  THR n 
4 26  GLN n 
4 27  GLU n 
4 28  CYS n 
4 29  ALA n 
4 30  ASN n 
4 31  VAL n 
4 32  VAL n 
4 33  VAL n 
4 34  GLY n 
4 35  TYR n 
4 36  GLY n 
4 37  VAL n 
4 38  TRP n 
4 39  PRO n 
4 40  GLU n 
4 41  TYR n 
4 42  LEU n 
4 43  LYS n 
4 44  ASP n 
4 45  ASN n 
4 46  GLU n 
4 47  ALA n 
4 48  THR n 
4 49  ALA n 
4 50  GLU n 
4 51  ASP n 
4 52  GLN n 
4 53  PRO n 
4 54  THR n 
4 55  GLN n 
4 56  PRO n 
4 57  ASP n 
4 58  VAL n 
4 59  ALA n 
4 60  THR n 
4 61  CYS n 
4 62  ARG n 
4 63  PHE n 
4 64  TYR n 
4 65  THR n 
4 66  LEU n 
4 67  GLU n 
4 68  SER n 
4 69  VAL n 
4 70  GLN n 
4 71  TRP n 
4 72  MET n 
4 73  LYS n 
4 74  ASN n 
4 75  SER n 
4 76  ALA n 
4 77  GLY n 
4 78  TRP n 
4 79  TRP n 
4 80  TRP n 
4 81  LYS n 
4 82  LEU n 
4 83  PRO n 
4 84  ASP n 
4 85  ALA n 
4 86  LEU n 
4 87  SER n 
4 88  GLN n 
4 89  MET n 
4 90  GLY n 
4 91  LEU n 
4 92  PHE n 
4 93  GLY n 
4 94  GLN n 
4 95  ASN n 
4 96  MET n 
4 97  GLN n 
4 98  TYR n 
4 99  HIS n 
4 100 TYR n 
4 101 LEU n 
4 102 GLY n 
4 103 ARG n 
4 104 THR n 
4 105 GLY n 
4 106 TYR n 
4 107 THR n 
4 108 ILE n 
4 109 HIS n 
4 110 VAL n 
4 111 GLN n 
4 112 CYS n 
4 113 ASN n 
4 114 ALA n 
4 115 SER n 
4 116 LYS n 
4 117 PHE n 
4 118 HIS n 
4 119 GLN n 
4 120 GLY n 
4 121 CYS n 
4 122 LEU n 
4 123 LEU n 
4 124 VAL n 
4 125 VAL n 
4 126 CYS n 
4 127 VAL n 
4 128 PRO n 
4 129 GLU n 
4 130 ALA n 
4 131 GLU n 
4 132 MET n 
4 133 GLY n 
4 134 CYS n 
4 135 SER n 
4 136 ASN n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 THR n 
4 141 PRO n 
4 142 GLU n 
4 143 PHE n 
4 144 SER n 
4 145 GLU n 
4 146 LEU n 
4 147 SER n 
4 148 GLY n 
4 149 GLY n 
4 150 ASP n 
4 151 SER n 
4 152 ALA n 
4 153 ARG n 
4 154 MET n 
4 155 PHE n 
4 156 THR n 
4 157 ASP n 
4 158 THR n 
4 159 GLN n 
4 160 VAL n 
4 161 GLY n 
4 162 GLU n 
4 163 SER n 
4 164 ASN n 
4 165 ALA n 
4 166 LYS n 
4 167 LYS n 
4 168 VAL n 
4 169 GLN n 
4 170 THR n 
4 171 ALA n 
4 172 VAL n 
4 173 TRP n 
4 174 ASN n 
4 175 ALA n 
4 176 GLY n 
4 177 MET n 
4 178 GLY n 
4 179 VAL n 
4 180 GLY n 
4 181 VAL n 
4 182 GLY n 
4 183 ASN n 
4 184 LEU n 
4 185 THR n 
4 186 ILE n 
4 187 PHE n 
4 188 PRO n 
4 189 HIS n 
4 190 GLN n 
4 191 TRP n 
4 192 ILE n 
4 193 ASN n 
4 194 LEU n 
4 195 ARG n 
4 196 THR n 
4 197 ASN n 
4 198 ASN n 
4 199 SER n 
4 200 ALA n 
4 201 THR n 
4 202 LEU n 
4 203 VAL n 
4 204 MET n 
4 205 PRO n 
4 206 TYR n 
4 207 ILE n 
4 208 ASN n 
4 209 SER n 
4 210 VAL n 
4 211 PRO n 
4 212 MET n 
4 213 ASP n 
4 214 ASN n 
4 215 MET n 
4 216 PHE n 
4 217 ARG n 
4 218 HIS n 
4 219 ASN n 
4 220 ASN n 
4 221 LEU n 
4 222 THR n 
4 223 LEU n 
4 224 MET n 
4 225 ILE n 
4 226 ILE n 
4 227 PRO n 
4 228 PHE n 
4 229 VAL n 
4 230 PRO n 
4 231 LEU n 
4 232 ASN n 
4 233 TYR n 
4 234 SER n 
4 235 GLU n 
4 236 GLY n 
4 237 SER n 
4 238 SER n 
4 239 PRO n 
4 240 TYR n 
4 241 VAL n 
4 242 PRO n 
4 243 ILE n 
4 244 THR n 
4 245 VAL n 
4 246 THR n 
4 247 ILE n 
4 248 ALA n 
4 249 PRO n 
4 250 MET n 
4 251 CYS n 
4 252 ALA n 
4 253 GLU n 
4 254 TYR n 
4 255 ASN n 
4 256 GLY n 
4 257 LEU n 
4 258 ARG n 
4 259 LEU n 
4 260 ALA n 
4 261 SER n 
4 262 ASN n 
4 263 GLN n 
5 1   GLY n 
5 2   LEU n 
5 3   PRO n 
5 4   VAL n 
5 5   MET n 
5 6   THR n 
5 7   THR n 
5 8   PRO n 
5 9   GLY n 
5 10  SER n 
5 11  THR n 
5 12  GLN n 
5 13  PHE n 
5 14  LEU n 
5 15  THR n 
5 16  SER n 
5 17  ASP n 
5 18  ASP n 
5 19  PHE n 
5 20  GLN n 
5 21  SER n 
5 22  PRO n 
5 23  SER n 
5 24  ALA n 
5 25  MET n 
5 26  PRO n 
5 27  GLN n 
5 28  PHE n 
5 29  ASP n 
5 30  VAL n 
5 31  THR n 
5 32  PRO n 
5 33  GLU n 
5 34  MET n 
5 35  GLN n 
5 36  ILE n 
5 37  PRO n 
5 38  GLY n 
5 39  ARG n 
5 40  VAL n 
5 41  ASN n 
5 42  ASN n 
5 43  LEU n 
5 44  MET n 
5 45  GLU n 
5 46  ILE n 
5 47  ALA n 
5 48  GLU n 
5 49  VAL n 
5 50  ASP n 
5 51  SER n 
5 52  VAL n 
5 53  VAL n 
5 54  PRO n 
5 55  VAL n 
5 56  ASN n 
5 57  ASN n 
5 58  THR n 
5 59  GLU n 
5 60  ASP n 
5 61  ASN n 
5 62  VAL n 
5 63  SER n 
5 64  SER n 
5 65  LEU n 
5 66  LYS n 
5 67  ALA n 
5 68  TYR n 
5 69  GLN n 
5 70  ILE n 
5 71  PRO n 
5 72  VAL n 
5 73  GLN n 
5 74  SER n 
5 75  ASN n 
5 76  SER n 
5 77  ASP n 
5 78  ASN n 
5 79  GLY n 
5 80  LYS n 
5 81  GLN n 
5 82  VAL n 
5 83  PHE n 
5 84  GLY n 
5 85  PHE n 
5 86  PRO n 
5 87  LEU n 
5 88  GLN n 
5 89  PRO n 
5 90  GLY n 
5 91  ALA n 
5 92  ASN n 
5 93  ASN n 
5 94  VAL n 
5 95  LEU n 
5 96  ASN n 
5 97  ARG n 
5 98  THR n 
5 99  LEU n 
5 100 LEU n 
5 101 GLY n 
5 102 GLU n 
5 103 ILE n 
5 104 LEU n 
5 105 ASN n 
5 106 TYR n 
5 107 TYR n 
5 108 THR n 
5 109 HIS n 
5 110 TRP n 
5 111 SER n 
5 112 GLY n 
5 113 SER n 
5 114 ILE n 
5 115 LYS n 
5 116 LEU n 
5 117 THR n 
5 118 PHE n 
5 119 MET n 
5 120 PHE n 
5 121 CYS n 
5 122 GLY n 
5 123 SER n 
5 124 ALA n 
5 125 MET n 
5 126 ALA n 
5 127 THR n 
5 128 GLY n 
5 129 LYS n 
5 130 PHE n 
5 131 LEU n 
5 132 LEU n 
5 133 ALA n 
5 134 TYR n 
5 135 SER n 
5 136 PRO n 
5 137 PRO n 
5 138 GLY n 
5 139 ALA n 
5 140 GLY n 
5 141 VAL n 
5 142 PRO n 
5 143 LYS n 
5 144 ASN n 
5 145 ARG n 
5 146 LYS n 
5 147 ASP n 
5 148 ALA n 
5 149 MET n 
5 150 LEU n 
5 151 GLY n 
5 152 THR n 
5 153 HIS n 
5 154 VAL n 
5 155 ILE n 
5 156 TRP n 
5 157 ASP n 
5 158 VAL n 
5 159 GLY n 
5 160 LEU n 
5 161 GLN n 
5 162 SER n 
5 163 SER n 
5 164 CYS n 
5 165 VAL n 
5 166 LEU n 
5 167 CYS n 
5 168 VAL n 
5 169 PRO n 
5 170 TRP n 
5 171 ILE n 
5 172 SER n 
5 173 GLN n 
5 174 THR n 
5 175 HIS n 
5 176 TYR n 
5 177 ARG n 
5 178 TYR n 
5 179 VAL n 
5 180 VAL n 
5 181 GLU n 
5 182 ASP n 
5 183 GLU n 
5 184 TYR n 
5 185 THR n 
5 186 ALA n 
5 187 ALA n 
5 188 GLY n 
5 189 TYR n 
5 190 VAL n 
5 191 THR n 
5 192 CYS n 
5 193 TRP n 
5 194 TYR n 
5 195 GLN n 
5 196 THR n 
5 197 ASN n 
5 198 ILE n 
5 199 VAL n 
5 200 VAL n 
5 201 PRO n 
5 202 ALA n 
5 203 ASP n 
5 204 VAL n 
5 205 GLN n 
5 206 SER n 
5 207 SER n 
5 208 CYS n 
5 209 ASP n 
5 210 ILE n 
5 211 LEU n 
5 212 CYS n 
5 213 PHE n 
5 214 VAL n 
5 215 SER n 
5 216 ALA n 
5 217 CYS n 
5 218 ASN n 
5 219 ASP n 
5 220 PHE n 
5 221 SER n 
5 222 VAL n 
5 223 ARG n 
5 224 MET n 
5 225 LEU n 
5 226 LYS n 
5 227 ASP n 
5 228 THR n 
5 229 PRO n 
5 230 PHE n 
5 231 ILE n 
5 232 ARG n 
5 233 GLN n 
5 234 ASP n 
5 235 THR n 
5 236 PHE n 
5 237 TYR n 
5 238 GLN n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 124 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 108 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 1 278 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 263 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 1 238 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7X3Y             7X3Y       ? 1 ? 1   
2 PDB 7X3Y             7X3Y       ? 2 ? 1   
3 UNP W8GTF7_9ENTO     W8GTF7     ? 3 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSEKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
1   
4 UNP A0A2S0RQC2_9ENTO A0A2S0RQC2 ? 4 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
70  
5 UNP L7UV52_9ENTO     L7UV52     ? 5 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7X3Y H 1 ? 124 ? 7X3Y       1   ? 124 ? 1 124 
2 2 7X3Y L 1 ? 108 ? 7X3Y       1   ? 108 ? 1 108 
3 3 7X3Y A 1 ? 278 ? W8GTF7     1   ? 278 ? 1 278 
4 4 7X3Y B 1 ? 263 ? A0A2S0RQC2 70  ? 332 ? 1 263 
5 5 7X3Y C 1 ? 238 ? L7UV52     333 ? 570 ? 1 238 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             7X3Y 
_struct_ref_seq_dif.mon_id                       LYS 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      84 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   W8GTF7 
_struct_ref_seq_dif.db_mon_id                    GLU 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          84 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            84 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7X3Y 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7X3Y 
_struct.title                        'Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7X3Y 
_struct_keywords.text            'Coxsackievirus B1, Neutralizing antibody, Cryo-EM, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 28  ? TYR A 32  ? THR H 28  TYR H 32  5 ? 5  
HELX_P HELX_P2  AA2 ASN A 53  ? GLY A 57  ? ASN H 53  GLY H 57  5 ? 5  
HELX_P HELX_P3  AA3 ARG A 89  ? SER A 93  ? ARG H 89  SER H 93  5 ? 5  
HELX_P HELX_P4  AA4 SER B 30  ? LEU B 34  ? SER L 30  LEU L 34  5 ? 5  
HELX_P HELX_P5  AA5 SER C 63  ? CYS C 69  ? SER A 63  CYS A 69  1 ? 7  
HELX_P HELX_P6  AA6 VAL C 97  ? GLU C 105 ? VAL A 97  GLU A 105 1 ? 9  
HELX_P HELX_P7  AA7 ASP C 156 ? GLN C 160 ? ASP A 156 GLN A 160 5 ? 5  
HELX_P HELX_P8  AA8 LEU D 82  ? LEU D 86  ? LEU B 82  LEU B 86  1 ? 5  
HELX_P HELX_P9  AA9 MET D 89  ? TYR D 98  ? MET B 89  TYR B 98  1 ? 10 
HELX_P HELX_P10 AB1 GLU D 142 ? SER D 147 ? GLU B 142 SER B 147 1 ? 6  
HELX_P HELX_P11 AB2 ALA D 171 ? ALA D 175 ? ALA B 171 ALA B 175 5 ? 5  
HELX_P HELX_P12 AB3 GLY D 180 ? PHE D 187 ? GLY B 180 PHE B 187 5 ? 8  
HELX_P HELX_P13 AB4 LEU E 43  ? GLU E 48  ? LEU C 43  GLU C 48  1 ? 6  
HELX_P HELX_P14 AB5 LEU E 65  ? GLN E 69  ? LEU C 65  GLN C 69  5 ? 5  
HELX_P HELX_P15 AB6 ASN E 144 ? LEU E 150 ? ASN C 144 LEU C 150 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22 SG ? ? ? 1_555 A CYS 98 SG ? ? H CYS 22 H CYS 98 1_555 ? ? ? ? ? ? ? 2.042 ? ? 
disulf2 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 89 SG ? ? L CYS 23 L CYS 89 1_555 ? ? ? ? ? ? ? 2.043 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7  B . ? SER 7  L PRO 8  B ? PRO 8  L 1 2.55 
2 TYR 95 B . ? TYR 95 L PRO 96 B ? PRO 96 L 1 4.38 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 7 ? 
AA3 ? 4 ? 
AA4 ? 6 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 8 ? 
AA9 ? 5 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 7 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 2 5 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA2 5 7 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA5 1 5 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 2 4 ? anti-parallel 
AA5 2 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 6 ? parallel      
AA8 2 8 ? anti-parallel 
AA8 3 8 ? anti-parallel 
AA8 4 8 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 5 7 ? anti-parallel 
AA8 5 8 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 5 ? anti-parallel 
AB1 2 5 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 3 5 ? anti-parallel 
AB1 3 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 3   ? SER A 7   ? LYS H 3   SER H 7   
AA1 2 SER A 17  ? SER A 25  ? SER H 17  SER H 25  
AA1 3 ILE A 80  ? ASN A 86  ? ILE H 80  ASN H 86  
AA1 4 THR A 71  ? ARG A 74  ? THR H 71  ARG H 74  
AA2 1 LEU A 11  ? VAL A 12  ? LEU H 11  VAL H 12  
AA2 2 TYR A 33  ? GLN A 39  ? TYR H 33  GLN H 39  
AA2 3 GLU A 46  ? LEU A 51  ? GLU H 46  LEU H 51  
AA2 4 THR A 60  ? TYR A 62  ? THR H 60  TYR H 62  
AA2 5 ALA A 94  ? SER A 101 ? ALA H 94  SER H 101 
AA2 6 TYR A 114 ? TRP A 115 ? TYR H 114 TRP H 115 
AA2 7 THR A 119 ? VAL A 123 ? THR H 119 VAL H 123 
AA3 1 LEU B 4   ? SER B 7   ? LEU L 4   SER L 7   
AA3 2 VAL B 19  ? ALA B 25  ? VAL L 19  ALA L 25  
AA3 3 SER B 71  ? ILE B 76  ? SER L 71  ILE L 76  
AA3 4 PHE B 63  ? SER B 68  ? PHE L 63  SER L 68  
AA4 1 ILE B 10  ? ALA B 13  ? ILE L 10  ALA L 13  
AA4 2 THR B 103 ? LEU B 107 ? THR L 103 LEU L 107 
AA4 3 THR B 86  ? GLN B 90  ? THR L 86  GLN L 90  
AA4 4 HIS B 35  ? GLN B 39  ? HIS L 35  GLN L 39  
AA4 5 LYS B 46  ? TYR B 50  ? LYS L 46  TYR L 50  
AA4 6 ASN B 54  ? LEU B 55  ? ASN L 54  LEU L 55  
AA5 1 ALA C 72  ? THR C 80  ? ALA A 72  THR A 80  
AA5 2 PHE C 107 ? GLN C 124 ? PHE A 107 GLN A 124 
AA5 3 MET C 178 ? ILE C 180 ? MET A 178 ILE A 180 
AA5 4 TYR C 189 ? SER C 190 ? TYR A 189 SER A 190 
AA5 5 ILE C 229 ? PRO C 247 ? ILE A 229 PRO A 247 
AA5 6 ARG E 39  ? VAL E 40  ? ARG C 39  VAL C 40  
AA6 1 ALA C 88  ? VAL C 91  ? ALA A 88  VAL A 91  
AA6 2 THR C 215 ? HIS C 220 ? THR A 215 HIS A 220 
AA6 3 THR C 138 ? VAL C 144 ? THR A 138 VAL A 144 
AA6 4 SER C 166 ? THR C 170 ? SER A 166 THR A 170 
AA7 1 ILE D 16  ? THR D 17  ? ILE B 16  THR B 17  
AA7 2 THR D 22  ? ILE D 23  ? THR B 22  ILE B 23  
AA8 1 VAL D 32  ? VAL D 33  ? VAL B 32  VAL B 33  
AA8 2 PRO D 53  ? THR D 54  ? PRO B 53  THR B 54  
AA8 3 TYR D 64  ? THR D 65  ? TYR B 64  THR B 65  
AA8 4 VAL D 69  ? TRP D 71  ? VAL B 69  TRP B 71  
AA8 5 LEU D 101 ? CYS D 112 ? LEU B 101 CYS B 112 
AA8 6 SER D 199 ? MET D 204 ? SER B 199 MET B 204 
AA8 7 ASP D 213 ? ASN D 214 ? ASP B 213 ASN B 214 
AA8 8 VAL D 241 ? ASN D 255 ? VAL B 241 ASN B 255 
AA9 1 ARG D 153 ? MET D 154 ? ARG B 153 MET B 154 
AA9 2 TRP D 78  ? LYS D 81  ? TRP B 78  LYS B 81  
AA9 3 LEU D 221 ? ASN D 232 ? LEU B 221 ASN B 232 
AA9 4 GLN D 119 ? PRO D 128 ? GLN B 119 PRO B 128 
AA9 5 HIS D 189 ? ASN D 193 ? HIS B 189 ASN B 193 
AB1 1 SER E 51  ? VAL E 52  ? SER C 51  VAL C 52  
AB1 2 ILE E 70  ? VAL E 72  ? ILE C 70  VAL C 72  
AB1 3 TYR E 107 ? CYS E 121 ? TYR C 107 CYS C 121 
AB1 4 SER E 163 ? ILE E 171 ? SER C 163 ILE C 171 
AB1 5 CYS E 208 ? VAL E 214 ? CYS C 208 VAL C 214 
AB1 6 SER E 221 ? LEU E 225 ? SER C 221 LEU C 225 
AB2 1 GLN E 81  ? PHE E 83  ? GLN C 81  PHE C 83  
AB2 2 CYS E 192 ? VAL E 199 ? CYS C 192 VAL C 199 
AB2 3 THR E 127 ? LEU E 132 ? THR C 127 LEU C 132 
AB2 4 ILE E 155 ? ASP E 157 ? ILE C 155 ASP C 157 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O SER A 21  ? O SER H 21  
AA1 2 3 N CYS A 22  ? N CYS H 22  O LEU A 81  ? O LEU H 81  
AA1 3 4 O GLN A 84  ? O GLN H 84  N THR A 71  ? N THR H 71  
AA2 1 7 N VAL A 12  ? N VAL H 12  O THR A 122 ? O THR H 122 
AA2 2 3 N TRP A 36  ? N TRP H 36  O LEU A 48  ? O LEU H 48  
AA2 2 5 N VAL A 37  ? N VAL H 37  O TYR A 97  ? O TYR H 97  
AA2 3 4 N PHE A 50  ? N PHE H 50  O GLU A 61  ? O GLU H 61  
AA2 5 6 N ARG A 100 ? N ARG H 100 O TYR A 114 ? O TYR H 114 
AA2 5 7 N TYR A 96  ? N TYR H 96  O THR A 119 ? O THR H 119 
AA3 1 2 N SER B 7   ? N SER L 7   O THR B 22  ? O THR L 22  
AA3 2 3 N CYS B 23  ? N CYS L 23  O TYR B 72  ? O TYR L 72  
AA3 3 4 O SER B 71  ? O SER L 71  N SER B 68  ? N SER L 68  
AA4 1 2 N MET B 11  ? N MET L 11  O GLU B 106 ? O GLU L 106 
AA4 2 3 O THR B 103 ? O THR L 103 N TYR B 87  ? N TYR L 87  
AA4 3 4 O THR B 86  ? O THR L 86  N GLN B 39  ? N GLN L 39  
AA4 4 5 N TRP B 36  ? N TRP L 36  O ILE B 49  ? O ILE L 49  
AA4 5 6 N TYR B 50  ? N TYR L 50  O ASN B 54  ? O ASN L 54  
AA5 1 5 N TYR C 79  ? N TYR A 79  O SER C 231 ? O SER A 231 
AA5 2 3 N LEU C 116 ? N LEU A 116 O MET C 178 ? O MET A 178 
AA5 2 4 N LEU C 110 ? N LEU A 110 O TYR C 189 ? O TYR A 189 
AA5 2 5 N ASP C 113 ? N ASP A 113 O LYS C 240 ? O LYS A 240 
AA5 5 6 N ALA C 244 ? N ALA A 244 O VAL E 40  ? O VAL C 40  
AA6 1 2 N TRP C 90  ? N TRP A 90  O LEU C 216 ? O LEU A 216 
AA6 2 3 O TYR C 217 ? O TYR A 217 N MET C 142 ? N MET A 142 
AA6 3 4 N ILE C 141 ? N ILE A 141 O VAL C 167 ? O VAL A 167 
AA7 1 2 N ILE D 16  ? N ILE B 16  O ILE D 23  ? O ILE B 23  
AA8 1 6 N VAL D 32  ? N VAL B 32  O THR D 201 ? O THR B 201 
AA8 2 8 N THR D 54  ? N THR B 54  O TYR D 254 ? O TYR B 254 
AA8 3 8 N TYR D 64  ? N TYR B 64  O ILE D 247 ? O ILE B 247 
AA8 4 8 N TRP D 71  ? N TRP B 71  O VAL D 241 ? O VAL B 241 
AA8 5 6 N VAL D 110 ? N VAL B 110 O ALA D 200 ? O ALA B 200 
AA8 5 7 N GLY D 102 ? N GLY B 102 O ASP D 213 ? O ASP B 213 
AA8 5 8 N HIS D 109 ? N HIS B 109 O THR D 246 ? O THR B 246 
AA9 1 2 O ARG D 153 ? O ARG B 153 N TRP D 79  ? N TRP B 79  
AA9 2 3 N TRP D 80  ? N TRP B 80  O LEU D 223 ? O LEU B 223 
AA9 3 4 O THR D 222 ? O THR B 222 N VAL D 127 ? N VAL B 127 
AA9 4 5 N LEU D 122 ? N LEU B 122 O ILE D 192 ? O ILE B 192 
AB1 1 5 N SER E 51  ? N SER C 51  O VAL E 214 ? O VAL C 214 
AB1 2 5 N VAL E 72  ? N VAL C 72  O CYS E 208 ? O CYS C 208 
AB1 3 4 N ILE E 114 ? N ILE C 114 O VAL E 168 ? O VAL C 168 
AB1 3 5 N THR E 117 ? N THR C 117 O PHE E 213 ? O PHE C 213 
AB1 3 6 N HIS E 109 ? N HIS C 109 O ARG E 223 ? O ARG C 223 
AB2 1 2 N VAL E 82  ? N VAL C 82  O CYS E 192 ? O CYS C 192 
AB2 2 3 O TRP E 193 ? O TRP C 193 N LEU E 131 ? N LEU C 131 
AB2 3 4 N PHE E 130 ? N PHE C 130 O TRP E 156 ? O TRP C 156 
# 
_atom_sites.entry_id                    7X3Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLU A 1 1   ? 346.621 387.358 499.800 1.00 105.36 ? 1   GLU H N   1 
ATOM 2    C CA  . GLU A 1 1   ? 347.767 387.048 500.642 1.00 105.36 ? 1   GLU H CA  1 
ATOM 3    C C   . GLU A 1 1   ? 347.931 385.542 500.784 1.00 105.36 ? 1   GLU H C   1 
ATOM 4    O O   . GLU A 1 1   ? 346.975 384.791 500.616 1.00 105.36 ? 1   GLU H O   1 
ATOM 5    C CB  . GLU A 1 1   ? 347.617 387.733 502.008 1.00 105.36 ? 1   GLU H CB  1 
ATOM 6    C CG  . GLU A 1 1   ? 346.467 387.243 502.889 1.00 105.36 ? 1   GLU H CG  1 
ATOM 7    C CD  . GLU A 1 1   ? 346.832 386.072 503.778 1.00 105.36 ? 1   GLU H CD  1 
ATOM 8    O OE1 . GLU A 1 1   ? 348.039 385.856 504.009 1.00 105.36 ? 1   GLU H OE1 1 
ATOM 9    O OE2 . GLU A 1 1   ? 345.913 385.366 504.242 1.00 105.36 ? 1   GLU H OE2 1 
ATOM 10   N N   . VAL A 1 2   ? 349.146 385.111 501.100 1.00 99.99  ? 2   VAL H N   1 
ATOM 11   C CA  . VAL A 1 2   ? 349.452 383.698 501.275 1.00 99.99  ? 2   VAL H CA  1 
ATOM 12   C C   . VAL A 1 2   ? 349.584 383.416 502.761 1.00 99.99  ? 2   VAL H C   1 
ATOM 13   O O   . VAL A 1 2   ? 350.309 384.118 503.471 1.00 99.99  ? 2   VAL H O   1 
ATOM 14   C CB  . VAL A 1 2   ? 350.732 383.315 500.527 1.00 99.99  ? 2   VAL H CB  1 
ATOM 15   C CG1 . VAL A 1 2   ? 350.879 381.814 500.474 1.00 99.99  ? 2   VAL H CG1 1 
ATOM 16   C CG2 . VAL A 1 2   ? 350.697 383.896 499.133 1.00 99.99  ? 2   VAL H CG2 1 
ATOM 17   N N   . LYS A 1 3   ? 348.889 382.391 503.234 1.00 101.03 ? 3   LYS H N   1 
ATOM 18   C CA  . LYS A 1 3   ? 348.896 382.032 504.646 1.00 101.03 ? 3   LYS H CA  1 
ATOM 19   C C   . LYS A 1 3   ? 349.048 380.524 504.754 1.00 101.03 ? 3   LYS H C   1 
ATOM 20   O O   . LYS A 1 3   ? 348.159 379.777 504.337 1.00 101.03 ? 3   LYS H O   1 
ATOM 21   C CB  . LYS A 1 3   ? 347.619 382.501 505.335 1.00 101.03 ? 3   LYS H CB  1 
ATOM 22   C CG  . LYS A 1 3   ? 347.594 382.256 506.825 1.00 101.03 ? 3   LYS H CG  1 
ATOM 23   C CD  . LYS A 1 3   ? 346.650 383.218 507.510 1.00 101.03 ? 3   LYS H CD  1 
ATOM 24   C CE  . LYS A 1 3   ? 346.639 383.001 509.006 1.00 101.03 ? 3   LYS H CE  1 
ATOM 25   N NZ  . LYS A 1 3   ? 348.006 383.089 509.581 1.00 101.03 ? 3   LYS H NZ  1 
ATOM 26   N N   . LEU A 1 4   ? 350.169 380.080 505.305 1.00 95.39  ? 4   LEU H N   1 
ATOM 27   C CA  . LEU A 1 4   ? 350.425 378.666 505.534 1.00 95.39  ? 4   LEU H CA  1 
ATOM 28   C C   . LEU A 1 4   ? 350.552 378.435 507.029 1.00 95.39  ? 4   LEU H C   1 
ATOM 29   O O   . LEU A 1 4   ? 351.602 378.716 507.612 1.00 95.39  ? 4   LEU H O   1 
ATOM 30   C CB  . LEU A 1 4   ? 351.701 378.211 504.830 1.00 95.39  ? 4   LEU H CB  1 
ATOM 31   C CG  . LEU A 1 4   ? 351.651 377.964 503.330 1.00 95.39  ? 4   LEU H CG  1 
ATOM 32   C CD1 . LEU A 1 4   ? 353.045 377.772 502.802 1.00 95.39  ? 4   LEU H CD1 1 
ATOM 33   C CD2 . LEU A 1 4   ? 350.829 376.750 503.046 1.00 95.39  ? 4   LEU H CD2 1 
ATOM 34   N N   . VAL A 1 5   ? 349.499 377.926 507.646 1.00 98.57  ? 5   VAL H N   1 
ATOM 35   C CA  . VAL A 1 5   ? 349.595 377.500 509.032 1.00 98.57  ? 5   VAL H CA  1 
ATOM 36   C C   . VAL A 1 5   ? 349.719 375.988 509.033 1.00 98.57  ? 5   VAL H C   1 
ATOM 37   O O   . VAL A 1 5   ? 349.402 375.318 508.045 1.00 98.57  ? 5   VAL H O   1 
ATOM 38   C CB  . VAL A 1 5   ? 348.400 377.955 509.897 1.00 98.57  ? 5   VAL H CB  1 
ATOM 39   C CG1 . VAL A 1 5   ? 348.138 379.425 509.697 1.00 98.57  ? 5   VAL H CG1 1 
ATOM 40   C CG2 . VAL A 1 5   ? 347.160 377.135 509.600 1.00 98.57  ? 5   VAL H CG2 1 
ATOM 41   N N   . GLU A 1 6   ? 350.218 375.453 510.138 1.00 101.66 ? 6   GLU H N   1 
ATOM 42   C CA  . GLU A 1 6   ? 350.312 374.016 510.298 1.00 101.66 ? 6   GLU H CA  1 
ATOM 43   C C   . GLU A 1 6   ? 350.169 373.660 511.766 1.00 101.66 ? 6   GLU H C   1 
ATOM 44   O O   . GLU A 1 6   ? 350.261 374.522 512.642 1.00 101.66 ? 6   GLU H O   1 
ATOM 45   C CB  . GLU A 1 6   ? 351.616 373.453 509.727 1.00 101.66 ? 6   GLU H CB  1 
ATOM 46   C CG  . GLU A 1 6   ? 352.865 373.862 510.439 1.00 101.66 ? 6   GLU H CG  1 
ATOM 47   C CD  . GLU A 1 6   ? 353.657 374.842 509.625 1.00 101.66 ? 6   GLU H CD  1 
ATOM 48   O OE1 . GLU A 1 6   ? 354.826 375.089 509.958 1.00 101.66 ? 6   GLU H OE1 1 
ATOM 49   O OE2 . GLU A 1 6   ? 353.105 375.372 508.644 1.00 101.66 ? 6   GLU H OE2 1 
ATOM 50   N N   . SER A 1 7   ? 349.922 372.379 512.018 1.00 104.65 ? 7   SER H N   1 
ATOM 51   C CA  . SER A 1 7   ? 349.581 371.907 513.351 1.00 104.65 ? 7   SER H CA  1 
ATOM 52   C C   . SER A 1 7   ? 349.832 370.411 513.423 1.00 104.65 ? 7   SER H C   1 
ATOM 53   O O   . SER A 1 7   ? 349.898 369.722 512.405 1.00 104.65 ? 7   SER H O   1 
ATOM 54   C CB  . SER A 1 7   ? 348.124 372.230 513.686 1.00 104.65 ? 7   SER H CB  1 
ATOM 55   O OG  . SER A 1 7   ? 347.251 371.560 512.795 1.00 104.65 ? 7   SER H OG  1 
ATOM 56   N N   . GLY A 1 8   ? 349.953 369.912 514.647 1.00 106.93 ? 8   GLY H N   1 
ATOM 57   C CA  . GLY A 1 8   ? 350.062 368.485 514.883 1.00 106.93 ? 8   GLY H CA  1 
ATOM 58   C C   . GLY A 1 8   ? 351.231 368.053 515.739 1.00 106.93 ? 8   GLY H C   1 
ATOM 59   O O   . GLY A 1 8   ? 351.266 366.885 516.150 1.00 106.93 ? 8   GLY H O   1 
ATOM 60   N N   . GLY A 1 9   ? 352.189 368.921 516.042 1.00 109.58 ? 9   GLY H N   1 
ATOM 61   C CA  . GLY A 1 9   ? 353.364 368.508 516.778 1.00 109.58 ? 9   GLY H CA  1 
ATOM 62   C C   . GLY A 1 9   ? 353.079 368.260 518.244 1.00 109.58 ? 9   GLY H C   1 
ATOM 63   O O   . GLY A 1 9   ? 352.059 368.669 518.798 1.00 109.58 ? 9   GLY H O   1 
ATOM 64   N N   . GLY A 1 10  ? 354.009 367.564 518.884 1.00 113.11 ? 10  GLY H N   1 
ATOM 65   C CA  . GLY A 1 10  ? 353.843 367.222 520.282 1.00 113.11 ? 10  GLY H CA  1 
ATOM 66   C C   . GLY A 1 10  ? 354.841 366.158 520.704 1.00 113.11 ? 10  GLY H C   1 
ATOM 67   O O   . GLY A 1 10  ? 355.847 365.931 520.038 1.00 113.11 ? 10  GLY H O   1 
ATOM 68   N N   . LEU A 1 11  ? 354.531 365.523 521.827 1.00 114.38 ? 11  LEU H N   1 
ATOM 69   C CA  . LEU A 1 11  ? 355.427 364.559 522.444 1.00 114.38 ? 11  LEU H CA  1 
ATOM 70   C C   . LEU A 1 11  ? 355.132 363.155 521.944 1.00 114.38 ? 11  LEU H C   1 
ATOM 71   O O   . LEU A 1 11  ? 353.982 362.813 521.655 1.00 114.38 ? 11  LEU H O   1 
ATOM 72   C CB  . LEU A 1 11  ? 355.304 364.600 523.966 1.00 114.38 ? 11  LEU H CB  1 
ATOM 73   C CG  . LEU A 1 11  ? 356.311 365.474 524.712 1.00 114.38 ? 11  LEU H CG  1 
ATOM 74   C CD1 . LEU A 1 11  ? 357.719 364.999 524.398 1.00 114.38 ? 11  LEU H CD1 1 
ATOM 75   C CD2 . LEU A 1 11  ? 356.144 366.958 524.407 1.00 114.38 ? 11  LEU H CD2 1 
ATOM 76   N N   . VAL A 1 12  ? 356.178 362.337 521.869 1.00 114.83 ? 12  VAL H N   1 
ATOM 77   C CA  . VAL A 1 12  ? 356.070 360.997 521.313 1.00 114.83 ? 12  VAL H CA  1 
ATOM 78   C C   . VAL A 1 12  ? 357.193 360.145 521.895 1.00 114.83 ? 12  VAL H C   1 
ATOM 79   O O   . VAL A 1 12  ? 358.318 360.615 522.079 1.00 114.83 ? 12  VAL H O   1 
ATOM 80   C CB  . VAL A 1 12  ? 356.086 361.060 519.765 1.00 114.83 ? 12  VAL H CB  1 
ATOM 81   C CG1 . VAL A 1 12  ? 357.271 361.859 519.277 1.00 114.83 ? 12  VAL H CG1 1 
ATOM 82   C CG2 . VAL A 1 12  ? 356.056 359.680 519.133 1.00 114.83 ? 12  VAL H CG2 1 
ATOM 83   N N   . GLN A 1 13  ? 356.861 358.907 522.248 1.00 117.20 ? 13  GLN H N   1 
ATOM 84   C CA  . GLN A 1 13  ? 357.868 357.943 522.653 1.00 117.20 ? 13  GLN H CA  1 
ATOM 85   C C   . GLN A 1 13  ? 358.691 357.518 521.437 1.00 117.20 ? 13  GLN H C   1 
ATOM 86   O O   . GLN A 1 13  ? 358.139 357.328 520.350 1.00 117.20 ? 13  GLN H O   1 
ATOM 87   C CB  . GLN A 1 13  ? 357.196 356.732 523.298 1.00 117.20 ? 13  GLN H CB  1 
ATOM 88   C CG  . GLN A 1 13  ? 358.034 355.465 523.391 1.00 117.20 ? 13  GLN H CG  1 
ATOM 89   C CD  . GLN A 1 13  ? 357.342 354.366 524.165 1.00 117.20 ? 13  GLN H CD  1 
ATOM 90   O OE1 . GLN A 1 13  ? 356.701 354.618 525.185 1.00 117.20 ? 13  GLN H OE1 1 
ATOM 91   N NE2 . GLN A 1 13  ? 357.465 353.136 523.682 1.00 117.20 ? 13  GLN H NE2 1 
ATOM 92   N N   . PRO A 1 14  ? 360.015 357.399 521.587 1.00 117.85 ? 14  PRO H N   1 
ATOM 93   C CA  . PRO A 1 14  ? 360.867 357.022 520.451 1.00 117.85 ? 14  PRO H CA  1 
ATOM 94   C C   . PRO A 1 14  ? 360.574 355.618 519.945 1.00 117.85 ? 14  PRO H C   1 
ATOM 95   O O   . PRO A 1 14  ? 360.604 354.643 520.697 1.00 117.85 ? 14  PRO H O   1 
ATOM 96   C CB  . PRO A 1 14  ? 362.283 357.121 521.026 1.00 117.85 ? 14  PRO H CB  1 
ATOM 97   C CG  . PRO A 1 14  ? 362.161 358.041 522.175 1.00 117.85 ? 14  PRO H CG  1 
ATOM 98   C CD  . PRO A 1 14  ? 360.815 357.775 522.760 1.00 117.85 ? 14  PRO H CD  1 
ATOM 99   N N   . GLY A 1 15  ? 360.303 355.531 518.648 1.00 115.45 ? 15  GLY H N   1 
ATOM 100  C CA  . GLY A 1 15  ? 359.809 354.320 518.038 1.00 115.45 ? 15  GLY H CA  1 
ATOM 101  C C   . GLY A 1 15  ? 358.331 354.334 517.725 1.00 115.45 ? 15  GLY H C   1 
ATOM 102  O O   . GLY A 1 15  ? 357.778 353.283 517.380 1.00 115.45 ? 15  GLY H O   1 
ATOM 103  N N   . GLY A 1 16  ? 357.673 355.486 517.836 1.00 114.84 ? 16  GLY H N   1 
ATOM 104  C CA  . GLY A 1 16  ? 356.255 355.597 517.585 1.00 114.84 ? 16  GLY H CA  1 
ATOM 105  C C   . GLY A 1 16  ? 355.947 356.278 516.263 1.00 114.84 ? 16  GLY H C   1 
ATOM 106  O O   . GLY A 1 16  ? 356.676 356.162 515.278 1.00 114.84 ? 16  GLY H O   1 
ATOM 107  N N   . SER A 1 17  ? 354.829 356.997 516.254 1.00 109.85 ? 17  SER H N   1 
ATOM 108  C CA  . SER A 1 17  ? 354.340 357.680 515.070 1.00 109.85 ? 17  SER H CA  1 
ATOM 109  C C   . SER A 1 17  ? 353.810 359.057 515.437 1.00 109.85 ? 17  SER H C   1 
ATOM 110  O O   . SER A 1 17  ? 353.562 359.358 516.608 1.00 109.85 ? 17  SER H O   1 
ATOM 111  C CB  . SER A 1 17  ? 353.232 356.880 514.380 1.00 109.85 ? 17  SER H CB  1 
ATOM 112  O OG  . SER A 1 17  ? 351.962 357.222 514.903 1.00 109.85 ? 17  SER H OG  1 
ATOM 113  N N   . LEU A 1 18  ? 353.626 359.883 514.408 1.00 107.11 ? 18  LEU H N   1 
ATOM 114  C CA  . LEU A 1 18  ? 353.102 361.236 514.542 1.00 107.11 ? 18  LEU H CA  1 
ATOM 115  C C   . LEU A 1 18  ? 352.689 361.711 513.160 1.00 107.11 ? 18  LEU H C   1 
ATOM 116  O O   . LEU A 1 18  ? 353.313 361.338 512.169 1.00 107.11 ? 18  LEU H O   1 
ATOM 117  C CB  . LEU A 1 18  ? 354.143 362.186 515.146 1.00 107.11 ? 18  LEU H CB  1 
ATOM 118  C CG  . LEU A 1 18  ? 353.722 363.599 515.534 1.00 107.11 ? 18  LEU H CG  1 
ATOM 119  C CD1 . LEU A 1 18  ? 352.428 363.585 516.303 1.00 107.11 ? 18  LEU H CD1 1 
ATOM 120  C CD2 . LEU A 1 18  ? 354.813 364.207 516.366 1.00 107.11 ? 18  LEU H CD2 1 
ATOM 121  N N   . SER A 1 19  ? 351.636 362.516 513.093 1.00 102.46 ? 19  SER H N   1 
ATOM 122  C CA  . SER A 1 19  ? 351.127 363.014 511.824 1.00 102.46 ? 19  SER H CA  1 
ATOM 123  C C   . SER A 1 19  ? 350.977 364.524 511.896 1.00 102.46 ? 19  SER H C   1 
ATOM 124  O O   . SER A 1 19  ? 350.156 365.031 512.666 1.00 102.46 ? 19  SER H O   1 
ATOM 125  C CB  . SER A 1 19  ? 349.790 362.368 511.473 1.00 102.46 ? 19  SER H CB  1 
ATOM 126  O OG  . SER A 1 19  ? 349.117 363.127 510.486 1.00 102.46 ? 19  SER H OG  1 
ATOM 127  N N   . LEU A 1 20  ? 351.759 365.233 511.096 1.00 97.48  ? 20  LEU H N   1 
ATOM 128  C CA  . LEU A 1 20  ? 351.622 366.671 510.975 1.00 97.48  ? 20  LEU H CA  1 
ATOM 129  C C   . LEU A 1 20  ? 350.625 367.007 509.878 1.00 97.48  ? 20  LEU H C   1 
ATOM 130  O O   . LEU A 1 20  ? 350.277 366.175 509.042 1.00 97.48  ? 20  LEU H O   1 
ATOM 131  C CB  . LEU A 1 20  ? 352.969 367.312 510.680 1.00 97.48  ? 20  LEU H CB  1 
ATOM 132  C CG  . LEU A 1 20  ? 354.030 367.041 511.734 1.00 97.48  ? 20  LEU H CG  1 
ATOM 133  C CD1 . LEU A 1 20  ? 355.316 367.692 511.331 1.00 97.48  ? 20  LEU H CD1 1 
ATOM 134  C CD2 . LEU A 1 20  ? 353.582 367.568 513.066 1.00 97.48  ? 20  LEU H CD2 1 
ATOM 135  N N   . SER A 1 21  ? 350.165 368.250 509.884 1.00 98.88  ? 21  SER H N   1 
ATOM 136  C CA  . SER A 1 21  ? 349.167 368.689 508.923 1.00 98.88  ? 21  SER H CA  1 
ATOM 137  C C   . SER A 1 21  ? 349.400 370.158 508.640 1.00 98.88  ? 21  SER H C   1 
ATOM 138  O O   . SER A 1 21  ? 349.594 370.930 509.577 1.00 98.88  ? 21  SER H O   1 
ATOM 139  C CB  . SER A 1 21  ? 347.754 368.475 509.462 1.00 98.88  ? 21  SER H CB  1 
ATOM 140  O OG  . SER A 1 21  ? 347.368 367.122 509.346 1.00 98.88  ? 21  SER H OG  1 
ATOM 141  N N   . CYS A 1 22  ? 349.371 370.539 507.367 1.00 99.33  ? 22  CYS H N   1 
ATOM 142  C CA  . CYS A 1 22  ? 349.616 371.910 506.936 1.00 99.33  ? 22  CYS H CA  1 
ATOM 143  C C   . CYS A 1 22  ? 348.375 372.413 506.218 1.00 99.33  ? 22  CYS H C   1 
ATOM 144  O O   . CYS A 1 22  ? 347.971 371.841 505.202 1.00 99.33  ? 22  CYS H O   1 
ATOM 145  C CB  . CYS A 1 22  ? 350.839 371.982 506.020 1.00 99.33  ? 22  CYS H CB  1 
ATOM 146  S SG  . CYS A 1 22  ? 351.390 373.639 505.544 1.00 99.33  ? 22  CYS H SG  1 
ATOM 147  N N   . ALA A 1 23  ? 347.767 373.469 506.746 1.00 99.11  ? 23  ALA H N   1 
ATOM 148  C CA  . ALA A 1 23  ? 346.560 374.037 506.168 1.00 99.11  ? 23  ALA H CA  1 
ATOM 149  C C   . ALA A 1 23  ? 346.905 375.258 505.328 1.00 99.11  ? 23  ALA H C   1 
ATOM 150  O O   . ALA A 1 23  ? 347.554 376.191 505.805 1.00 99.11  ? 23  ALA H O   1 
ATOM 151  C CB  . ALA A 1 23  ? 345.561 374.419 507.257 1.00 99.11  ? 23  ALA H CB  1 
ATOM 152  N N   . ALA A 1 24  ? 346.451 375.253 504.081 1.00 97.34  ? 24  ALA H N   1 
ATOM 153  C CA  . ALA A 1 24  ? 346.830 376.255 503.100 1.00 97.34  ? 24  ALA H CA  1 
ATOM 154  C C   . ALA A 1 24  ? 345.617 377.054 502.661 1.00 97.34  ? 24  ALA H C   1 
ATOM 155  O O   . ALA A 1 24  ? 344.579 376.485 502.313 1.00 97.34  ? 24  ALA H O   1 
ATOM 156  C CB  . ALA A 1 24  ? 347.475 375.607 501.879 1.00 97.34  ? 24  ALA H CB  1 
ATOM 157  N N   . SER A 1 25  ? 345.764 378.374 502.655 1.00 97.66  ? 25  SER H N   1 
ATOM 158  C CA  . SER A 1 25  ? 344.697 379.261 502.226 1.00 97.66  ? 25  SER H CA  1 
ATOM 159  C C   . SER A 1 25  ? 345.316 380.500 501.608 1.00 97.66  ? 25  SER H C   1 
ATOM 160  O O   . SER A 1 25  ? 346.340 380.992 502.084 1.00 97.66  ? 25  SER H O   1 
ATOM 161  C CB  . SER A 1 25  ? 343.791 379.655 503.392 1.00 97.66  ? 25  SER H CB  1 
ATOM 162  O OG  . SER A 1 25  ? 344.432 380.601 504.228 1.00 97.66  ? 25  SER H OG  1 
ATOM 163  N N   . GLY A 1 26  ? 344.689 380.995 500.548 1.00 94.95  ? 26  GLY H N   1 
ATOM 164  C CA  . GLY A 1 26  ? 345.146 382.190 499.873 1.00 94.95  ? 26  GLY H CA  1 
ATOM 165  C C   . GLY A 1 26  ? 345.645 381.977 498.465 1.00 94.95  ? 26  GLY H C   1 
ATOM 166  O O   . GLY A 1 26  ? 346.120 382.936 497.847 1.00 94.95  ? 26  GLY H O   1 
ATOM 167  N N   . PHE A 1 27  ? 345.556 380.760 497.939 1.00 91.69  ? 27  PHE H N   1 
ATOM 168  C CA  . PHE A 1 27  ? 346.010 380.450 496.592 1.00 91.69  ? 27  PHE H CA  1 
ATOM 169  C C   . PHE A 1 27  ? 345.324 379.169 496.152 1.00 91.69  ? 27  PHE H C   1 
ATOM 170  O O   . PHE A 1 27  ? 344.724 378.455 496.958 1.00 91.69  ? 27  PHE H O   1 
ATOM 171  C CB  . PHE A 1 27  ? 347.539 380.311 496.518 1.00 91.69  ? 27  PHE H CB  1 
ATOM 172  C CG  . PHE A 1 27  ? 348.117 379.312 497.487 1.00 91.69  ? 27  PHE H CG  1 
ATOM 173  C CD1 . PHE A 1 27  ? 348.485 379.694 498.762 1.00 91.69  ? 27  PHE H CD1 1 
ATOM 174  C CD2 . PHE A 1 27  ? 348.325 378.001 497.112 1.00 91.69  ? 27  PHE H CD2 1 
ATOM 175  C CE1 . PHE A 1 27  ? 349.019 378.786 499.645 1.00 91.69  ? 27  PHE H CE1 1 
ATOM 176  C CE2 . PHE A 1 27  ? 348.856 377.094 497.996 1.00 91.69  ? 27  PHE H CE2 1 
ATOM 177  C CZ  . PHE A 1 27  ? 349.204 377.490 499.260 1.00 91.69  ? 27  PHE H CZ  1 
ATOM 178  N N   . THR A 1 28  ? 345.428 378.878 494.861 1.00 89.97  ? 28  THR H N   1 
ATOM 179  C CA  . THR A 1 28  ? 344.940 377.612 494.337 1.00 89.97  ? 28  THR H CA  1 
ATOM 180  C C   . THR A 1 28  ? 345.905 376.510 494.746 1.00 89.97  ? 28  THR H C   1 
ATOM 181  O O   . THR A 1 28  ? 347.102 376.594 494.459 1.00 89.97  ? 28  THR H O   1 
ATOM 182  C CB  . THR A 1 28  ? 344.809 377.675 492.823 1.00 89.97  ? 28  THR H CB  1 
ATOM 183  O OG1 . THR A 1 28  ? 344.274 378.948 492.445 1.00 89.97  ? 28  THR H OG1 1 
ATOM 184  C CG2 . THR A 1 28  ? 343.886 376.582 492.341 1.00 89.97  ? 28  THR H CG2 1 
ATOM 185  N N   . PHE A 1 29  ? 345.392 375.483 495.417 1.00 89.31  ? 29  PHE H N   1 
ATOM 186  C CA  . PHE A 1 29  ? 346.264 374.498 496.041 1.00 89.31  ? 29  PHE H CA  1 
ATOM 187  C C   . PHE A 1 29  ? 346.889 373.535 495.048 1.00 89.31  ? 29  PHE H C   1 
ATOM 188  O O   . PHE A 1 29  ? 348.001 373.061 495.290 1.00 89.31  ? 29  PHE H O   1 
ATOM 189  C CB  . PHE A 1 29  ? 345.498 373.700 497.094 1.00 89.31  ? 29  PHE H CB  1 
ATOM 190  C CG  . PHE A 1 29  ? 346.373 372.838 497.949 1.00 89.31  ? 29  PHE H CG  1 
ATOM 191  C CD1 . PHE A 1 29  ? 347.126 373.392 498.962 1.00 89.31  ? 29  PHE H CD1 1 
ATOM 192  C CD2 . PHE A 1 29  ? 346.448 371.473 497.734 1.00 89.31  ? 29  PHE H CD2 1 
ATOM 193  C CE1 . PHE A 1 29  ? 347.932 372.602 499.750 1.00 89.31  ? 29  PHE H CE1 1 
ATOM 194  C CE2 . PHE A 1 29  ? 347.255 370.679 498.514 1.00 89.31  ? 29  PHE H CE2 1 
ATOM 195  C CZ  . PHE A 1 29  ? 347.996 371.244 499.523 1.00 89.31  ? 29  PHE H CZ  1 
ATOM 196  N N   . THR A 1 30  ? 346.222 373.241 493.938 1.00 80.45  ? 30  THR H N   1 
ATOM 197  C CA  . THR A 1 30  ? 346.676 372.196 493.033 1.00 80.45  ? 30  THR H CA  1 
ATOM 198  C C   . THR A 1 30  ? 347.641 372.701 491.973 1.00 80.45  ? 30  THR H C   1 
ATOM 199  O O   . THR A 1 30  ? 347.796 372.053 490.934 1.00 80.45  ? 30  THR H O   1 
ATOM 200  C CB  . THR A 1 30  ? 345.477 371.529 492.366 1.00 80.45  ? 30  THR H CB  1 
ATOM 201  O OG1 . THR A 1 30  ? 344.984 372.373 491.324 1.00 80.45  ? 30  THR H OG1 1 
ATOM 202  C CG2 . THR A 1 30  ? 344.374 371.312 493.371 1.00 80.45  ? 30  THR H CG2 1 
ATOM 203  N N   . ASP A 1 31  ? 348.289 373.843 492.189 1.00 79.50  ? 31  ASP H N   1 
ATOM 204  C CA  . ASP A 1 31  ? 349.177 374.407 491.184 1.00 79.50  ? 31  ASP H CA  1 
ATOM 205  C C   . ASP A 1 31  ? 350.603 374.643 491.642 1.00 79.50  ? 31  ASP H C   1 
ATOM 206  O O   . ASP A 1 31  ? 351.403 375.129 490.839 1.00 79.50  ? 31  ASP H O   1 
ATOM 207  C CB  . ASP A 1 31  ? 348.627 375.737 490.653 1.00 79.50  ? 31  ASP H CB  1 
ATOM 208  C CG  . ASP A 1 31  ? 347.221 375.615 490.124 1.00 79.50  ? 31  ASP H CG  1 
ATOM 209  O OD1 . ASP A 1 31  ? 346.864 374.533 489.617 1.00 79.50  ? 31  ASP H OD1 1 
ATOM 210  O OD2 . ASP A 1 31  ? 346.468 376.603 490.193 1.00 79.50  ? 31  ASP H OD2 1 
ATOM 211  N N   . TYR A 1 32  ? 350.957 374.328 492.878 1.00 76.71  ? 32  TYR H N   1 
ATOM 212  C CA  . TYR A 1 32  ? 352.296 374.614 493.359 1.00 76.71  ? 32  TYR H CA  1 
ATOM 213  C C   . TYR A 1 32  ? 352.893 373.388 494.023 1.00 76.71  ? 32  TYR H C   1 
ATOM 214  O O   . TYR A 1 32  ? 352.180 372.482 494.453 1.00 76.71  ? 32  TYR H O   1 
ATOM 215  C CB  . TYR A 1 32  ? 352.292 375.792 494.326 1.00 76.71  ? 32  TYR H CB  1 
ATOM 216  C CG  . TYR A 1 32  ? 351.713 377.039 493.713 1.00 76.71  ? 32  TYR H CG  1 
ATOM 217  C CD1 . TYR A 1 32  ? 352.469 377.829 492.862 1.00 76.71  ? 32  TYR H CD1 1 
ATOM 218  C CD2 . TYR A 1 32  ? 350.407 377.414 493.967 1.00 76.71  ? 32  TYR H CD2 1 
ATOM 219  C CE1 . TYR A 1 32  ? 351.941 378.962 492.291 1.00 76.71  ? 32  TYR H CE1 1 
ATOM 220  C CE2 . TYR A 1 32  ? 349.874 378.543 493.402 1.00 76.71  ? 32  TYR H CE2 1 
ATOM 221  C CZ  . TYR A 1 32  ? 350.644 379.312 492.566 1.00 76.71  ? 32  TYR H CZ  1 
ATOM 222  O OH  . TYR A 1 32  ? 350.103 380.440 492.002 1.00 76.71  ? 32  TYR H OH  1 
ATOM 223  N N   . TYR A 1 33  ? 354.218 373.362 494.074 1.00 72.10  ? 33  TYR H N   1 
ATOM 224  C CA  . TYR A 1 33  ? 354.928 372.313 494.782 1.00 72.10  ? 33  TYR H CA  1 
ATOM 225  C C   . TYR A 1 33  ? 354.963 372.661 496.257 1.00 72.10  ? 33  TYR H C   1 
ATOM 226  O O   . TYR A 1 33  ? 355.166 373.818 496.622 1.00 72.10  ? 33  TYR H O   1 
ATOM 227  C CB  . TYR A 1 33  ? 356.355 372.180 494.262 1.00 72.10  ? 33  TYR H CB  1 
ATOM 228  C CG  . TYR A 1 33  ? 356.544 371.506 492.920 1.00 72.10  ? 33  TYR H CG  1 
ATOM 229  C CD1 . TYR A 1 33  ? 355.877 371.940 491.788 1.00 72.10  ? 33  TYR H CD1 1 
ATOM 230  C CD2 . TYR A 1 33  ? 357.437 370.468 492.783 1.00 72.10  ? 33  TYR H CD2 1 
ATOM 231  C CE1 . TYR A 1 33  ? 356.068 371.338 490.582 1.00 72.10  ? 33  TYR H CE1 1 
ATOM 232  C CE2 . TYR A 1 33  ? 357.632 369.862 491.577 1.00 72.10  ? 33  TYR H CE2 1 
ATOM 233  C CZ  . TYR A 1 33  ? 356.948 370.303 490.482 1.00 72.10  ? 33  TYR H CZ  1 
ATOM 234  O OH  . TYR A 1 33  ? 357.149 369.694 489.274 1.00 72.10  ? 33  TYR H OH  1 
ATOM 235  N N   . MET A 1 34  ? 354.765 371.668 497.114 1.00 78.54  ? 34  MET H N   1 
ATOM 236  C CA  . MET A 1 34  ? 354.697 371.898 498.551 1.00 78.54  ? 34  MET H CA  1 
ATOM 237  C C   . MET A 1 34  ? 355.753 371.051 499.240 1.00 78.54  ? 34  MET H C   1 
ATOM 238  O O   . MET A 1 34  ? 355.785 369.834 499.055 1.00 78.54  ? 34  MET H O   1 
ATOM 239  C CB  . MET A 1 34  ? 353.308 371.575 499.086 1.00 78.54  ? 34  MET H CB  1 
ATOM 240  C CG  . MET A 1 34  ? 352.202 372.316 498.383 1.00 78.54  ? 34  MET H CG  1 
ATOM 241  S SD  . MET A 1 34  ? 352.068 374.014 498.929 1.00 78.54  ? 34  MET H SD  1 
ATOM 242  C CE  . MET A 1 34  ? 351.355 373.775 500.544 1.00 78.54  ? 34  MET H CE  1 
ATOM 243  N N   . ASN A 1 35  ? 356.593 371.693 500.049 1.00 80.22  ? 35  ASN H N   1 
ATOM 244  C CA  . ASN A 1 35  ? 357.797 371.097 500.603 1.00 80.22  ? 35  ASN H CA  1 
ATOM 245  C C   . ASN A 1 35  ? 357.659 370.860 502.105 1.00 80.22  ? 35  ASN H C   1 
ATOM 246  O O   . ASN A 1 35  ? 356.732 371.338 502.756 1.00 80.22  ? 35  ASN H O   1 
ATOM 247  C CB  . ASN A 1 35  ? 359.000 371.994 500.326 1.00 80.22  ? 35  ASN H CB  1 
ATOM 248  C CG  . ASN A 1 35  ? 359.300 372.137 498.859 1.00 80.22  ? 35  ASN H CG  1 
ATOM 249  O OD1 . ASN A 1 35  ? 360.223 371.520 498.346 1.00 80.22  ? 35  ASN H OD1 1 
ATOM 250  N ND2 . ASN A 1 35  ? 358.542 372.974 498.178 1.00 80.22  ? 35  ASN H ND2 1 
ATOM 251  N N   . TRP A 1 36  ? 358.623 370.130 502.664 1.00 86.17  ? 36  TRP H N   1 
ATOM 252  C CA  . TRP A 1 36  ? 358.683 369.862 504.098 1.00 86.17  ? 36  TRP H CA  1 
ATOM 253  C C   . TRP A 1 36  ? 360.124 370.023 504.542 1.00 86.17  ? 36  TRP H C   1 
ATOM 254  O O   . TRP A 1 36  ? 360.992 369.283 504.081 1.00 86.17  ? 36  TRP H O   1 
ATOM 255  C CB  . TRP A 1 36  ? 358.190 368.459 504.428 1.00 86.17  ? 36  TRP H CB  1 
ATOM 256  C CG  . TRP A 1 36  ? 356.721 368.335 504.481 1.00 86.17  ? 36  TRP H CG  1 
ATOM 257  C CD1 . TRP A 1 36  ? 355.927 367.755 503.556 1.00 86.17  ? 36  TRP H CD1 1 
ATOM 258  C CD2 . TRP A 1 36  ? 355.857 368.798 505.519 1.00 86.17  ? 36  TRP H CD2 1 
ATOM 259  N NE1 . TRP A 1 36  ? 354.617 367.828 503.943 1.00 86.17  ? 36  TRP H NE1 1 
ATOM 260  C CE2 . TRP A 1 36  ? 354.549 368.465 505.150 1.00 86.17  ? 36  TRP H CE2 1 
ATOM 261  C CE3 . TRP A 1 36  ? 356.064 369.459 506.726 1.00 86.17  ? 36  TRP H CE3 1 
ATOM 262  C CZ2 . TRP A 1 36  ? 353.457 368.776 505.936 1.00 86.17  ? 36  TRP H CZ2 1 
ATOM 263  C CZ3 . TRP A 1 36  ? 354.981 369.771 507.500 1.00 86.17  ? 36  TRP H CZ3 1 
ATOM 264  C CH2 . TRP A 1 36  ? 353.695 369.426 507.108 1.00 86.17  ? 36  TRP H CH2 1 
ATOM 265  N N   . VAL A 1 37  ? 360.385 370.991 505.415 1.00 87.33  ? 37  VAL H N   1 
ATOM 266  C CA  . VAL A 1 37  ? 361.733 371.315 505.866 1.00 87.33  ? 37  VAL H CA  1 
ATOM 267  C C   . VAL A 1 37  ? 361.723 371.257 507.385 1.00 87.33  ? 37  VAL H C   1 
ATOM 268  O O   . VAL A 1 37  ? 360.764 371.713 508.013 1.00 87.33  ? 37  VAL H O   1 
ATOM 269  C CB  . VAL A 1 37  ? 362.176 372.706 505.376 1.00 87.33  ? 37  VAL H CB  1 
ATOM 270  C CG1 . VAL A 1 37  ? 363.584 373.037 505.820 1.00 87.33  ? 37  VAL H CG1 1 
ATOM 271  C CG2 . VAL A 1 37  ? 362.077 372.810 503.875 1.00 87.33  ? 37  VAL H CG2 1 
ATOM 272  N N   . ARG A 1 38  ? 362.767 370.689 507.977 1.00 91.98  ? 38  ARG H N   1 
ATOM 273  C CA  . ARG A 1 38  ? 362.915 370.698 509.423 1.00 91.98  ? 38  ARG H CA  1 
ATOM 274  C C   . ARG A 1 38  ? 364.196 371.412 509.831 1.00 91.98  ? 38  ARG H C   1 
ATOM 275  O O   . ARG A 1 38  ? 365.157 371.511 509.067 1.00 91.98  ? 38  ARG H O   1 
ATOM 276  C CB  . ARG A 1 38  ? 362.903 369.276 509.990 1.00 91.98  ? 38  ARG H CB  1 
ATOM 277  C CG  . ARG A 1 38  ? 364.214 368.519 509.905 1.00 91.98  ? 38  ARG H CG  1 
ATOM 278  C CD  . ARG A 1 38  ? 364.108 367.210 510.656 1.00 91.98  ? 38  ARG H CD  1 
ATOM 279  N NE  . ARG A 1 38  ? 365.151 366.263 510.287 1.00 91.98  ? 38  ARG H NE  1 
ATOM 280  C CZ  . ARG A 1 38  ? 365.091 364.963 510.545 1.00 91.98  ? 38  ARG H CZ  1 
ATOM 281  N NH1 . ARG A 1 38  ? 364.041 364.462 511.171 1.00 91.98  ? 38  ARG H NH1 1 
ATOM 282  N NH2 . ARG A 1 38  ? 366.078 364.164 510.178 1.00 91.98  ? 38  ARG H NH2 1 
ATOM 283  N N   . GLN A 1 39  ? 364.189 371.932 511.056 1.00 97.96  ? 39  GLN H N   1 
ATOM 284  C CA  . GLN A 1 39  ? 365.352 372.580 511.606 1.00 97.96  ? 39  GLN H CA  1 
ATOM 285  C C   . GLN A 1 39  ? 365.434 372.264 513.090 1.00 97.96  ? 39  GLN H C   1 
ATOM 286  O O   . GLN A 1 39  ? 364.470 372.538 513.822 1.00 97.96  ? 39  GLN H O   1 
ATOM 287  C CB  . GLN A 1 39  ? 365.332 374.091 511.419 1.00 97.96  ? 39  GLN H CB  1 
ATOM 288  C CG  . GLN A 1 39  ? 366.544 374.758 512.026 1.00 97.96  ? 39  GLN H CG  1 
ATOM 289  C CD  . GLN A 1 39  ? 366.483 376.259 511.974 1.00 97.96  ? 39  GLN H CD  1 
ATOM 290  O OE1 . GLN A 1 39  ? 365.408 376.849 511.981 1.00 97.96  ? 39  GLN H OE1 1 
ATOM 291  N NE2 . GLN A 1 39  ? 367.645 376.891 511.921 1.00 97.96  ? 39  GLN H NE2 1 
ATOM 292  N N   . PRO A 1 40  ? 366.552 371.722 513.562 1.00 101.82 ? 40  PRO H N   1 
ATOM 293  C CA  . PRO A 1 40  ? 366.708 371.476 514.997 1.00 101.82 ? 40  PRO H CA  1 
ATOM 294  C C   . PRO A 1 40  ? 366.994 372.752 515.771 1.00 101.82 ? 40  PRO H C   1 
ATOM 295  O O   . PRO A 1 40  ? 366.932 373.854 515.219 1.00 101.82 ? 40  PRO H O   1 
ATOM 296  C CB  . PRO A 1 40  ? 367.895 370.507 515.058 1.00 101.82 ? 40  PRO H CB  1 
ATOM 297  C CG  . PRO A 1 40  ? 368.171 370.111 513.644 1.00 101.82 ? 40  PRO H CG  1 
ATOM 298  C CD  . PRO A 1 40  ? 367.716 371.243 512.810 1.00 101.82 ? 40  PRO H CD  1 
ATOM 299  N N   . SER A 1 41  ? 367.310 372.614 517.055 1.00 105.71 ? 41  SER H N   1 
ATOM 300  C CA  . SER A 1 41  ? 367.534 373.777 517.901 1.00 105.71 ? 41  SER H CA  1 
ATOM 301  C C   . SER A 1 41  ? 368.839 374.476 517.544 1.00 105.71 ? 41  SER H C   1 
ATOM 302  O O   . SER A 1 41  ? 369.922 374.042 517.951 1.00 105.71 ? 41  SER H O   1 
ATOM 303  C CB  . SER A 1 41  ? 367.533 373.365 519.372 1.00 105.71 ? 41  SER H CB  1 
ATOM 304  O OG  . SER A 1 41  ? 367.753 374.480 520.216 1.00 105.71 ? 41  SER H OG  1 
ATOM 305  N N   . GLY A 1 42  ? 368.738 375.555 516.771 1.00 105.68 ? 42  GLY H N   1 
ATOM 306  C CA  . GLY A 1 42  ? 369.891 376.372 516.448 1.00 105.68 ? 42  GLY H CA  1 
ATOM 307  C C   . GLY A 1 42  ? 370.885 375.740 515.502 1.00 105.68 ? 42  GLY H C   1 
ATOM 308  O O   . GLY A 1 42  ? 372.079 376.034 515.586 1.00 105.68 ? 42  GLY H O   1 
ATOM 309  N N   . LYS A 1 43  ? 370.431 374.878 514.606 1.00 104.18 ? 43  LYS H N   1 
ATOM 310  C CA  . LYS A 1 43  ? 371.304 374.212 513.650 1.00 104.18 ? 43  LYS H CA  1 
ATOM 311  C C   . LYS A 1 43  ? 370.909 374.637 512.236 1.00 104.18 ? 43  LYS H C   1 
ATOM 312  O O   . LYS A 1 43  ? 370.104 375.551 512.040 1.00 104.18 ? 43  LYS H O   1 
ATOM 313  C CB  . LYS A 1 43  ? 371.245 372.690 513.821 1.00 104.18 ? 43  LYS H CB  1 
ATOM 314  C CG  . LYS A 1 43  ? 371.224 372.172 515.263 1.00 104.18 ? 43  LYS H CG  1 
ATOM 315  C CD  . LYS A 1 43  ? 372.397 372.669 516.111 1.00 104.18 ? 43  LYS H CD  1 
ATOM 316  C CE  . LYS A 1 43  ? 373.715 372.054 515.678 1.00 104.18 ? 43  LYS H CE  1 
ATOM 317  N NZ  . LYS A 1 43  ? 373.681 370.573 515.735 1.00 104.18 ? 43  LYS H NZ  1 
ATOM 318  N N   . ALA A 1 44  ? 371.494 373.973 511.244 1.00 99.51  ? 44  ALA H N   1 
ATOM 319  C CA  . ALA A 1 44  ? 371.170 374.275 509.860 1.00 99.51  ? 44  ALA H CA  1 
ATOM 320  C C   . ALA A 1 44  ? 369.848 373.627 509.461 1.00 99.51  ? 44  ALA H C   1 
ATOM 321  O O   . ALA A 1 44  ? 369.315 372.756 510.150 1.00 99.51  ? 44  ALA H O   1 
ATOM 322  C CB  . ALA A 1 44  ? 372.283 373.802 508.929 1.00 99.51  ? 44  ALA H CB  1 
ATOM 323  N N   . LEU A 1 45  ? 369.319 374.072 508.328 1.00 92.06  ? 45  LEU H N   1 
ATOM 324  C CA  . LEU A 1 45  ? 368.063 373.563 507.811 1.00 92.06  ? 45  LEU H CA  1 
ATOM 325  C C   . LEU A 1 45  ? 368.283 372.237 507.091 1.00 92.06  ? 45  LEU H C   1 
ATOM 326  O O   . LEU A 1 45  ? 369.390 371.912 506.664 1.00 92.06  ? 45  LEU H O   1 
ATOM 327  C CB  . LEU A 1 45  ? 367.440 374.580 506.865 1.00 92.06  ? 45  LEU H CB  1 
ATOM 328  C CG  . LEU A 1 45  ? 367.279 375.991 507.421 1.00 92.06  ? 45  LEU H CG  1 
ATOM 329  C CD1 . LEU A 1 45  ? 367.029 376.962 506.304 1.00 92.06  ? 45  LEU H CD1 1 
ATOM 330  C CD2 . LEU A 1 45  ? 366.135 376.041 508.378 1.00 92.06  ? 45  LEU H CD2 1 
ATOM 331  N N   . GLU A 1 46  ? 367.213 371.461 506.963 1.00 88.80  ? 46  GLU H N   1 
ATOM 332  C CA  . GLU A 1 46  ? 367.298 370.179 506.282 1.00 88.80  ? 46  GLU H CA  1 
ATOM 333  C C   . GLU A 1 46  ? 365.999 369.892 505.552 1.00 88.80  ? 46  GLU H C   1 
ATOM 334  O O   . GLU A 1 46  ? 364.929 369.867 506.160 1.00 88.80  ? 46  GLU H O   1 
ATOM 335  C CB  . GLU A 1 46  ? 367.604 369.042 507.250 1.00 88.80  ? 46  GLU H CB  1 
ATOM 336  C CG  . GLU A 1 46  ? 368.195 367.829 506.572 1.00 88.80  ? 46  GLU H CG  1 
ATOM 337  C CD  . GLU A 1 46  ? 368.171 366.597 507.448 1.00 88.80  ? 46  GLU H CD  1 
ATOM 338  O OE1 . GLU A 1 46  ? 367.384 366.570 508.416 1.00 88.80  ? 46  GLU H OE1 1 
ATOM 339  O OE2 . GLU A 1 46  ? 368.941 365.656 507.167 1.00 88.80  ? 46  GLU H OE2 1 
ATOM 340  N N   . TRP A 1 47  ? 366.106 369.667 504.250 1.00 79.51  ? 47  TRP H N   1 
ATOM 341  C CA  . TRP A 1 47  ? 364.962 369.481 503.373 1.00 79.51  ? 47  TRP H CA  1 
ATOM 342  C C   . TRP A 1 47  ? 364.583 368.013 503.346 1.00 79.51  ? 47  TRP H C   1 
ATOM 343  O O   . TRP A 1 47  ? 365.431 367.151 503.111 1.00 79.51  ? 47  TRP H O   1 
ATOM 344  C CB  . TRP A 1 47  ? 365.300 369.976 501.970 1.00 79.51  ? 47  TRP H CB  1 
ATOM 345  C CG  . TRP A 1 47  ? 364.348 369.591 500.902 1.00 79.51  ? 47  TRP H CG  1 
ATOM 346  C CD1 . TRP A 1 47  ? 363.228 370.253 500.535 1.00 79.51  ? 47  TRP H CD1 1 
ATOM 347  C CD2 . TRP A 1 47  ? 364.458 368.471 500.027 1.00 79.51  ? 47  TRP H CD2 1 
ATOM 348  N NE1 . TRP A 1 47  ? 362.615 369.607 499.499 1.00 79.51  ? 47  TRP H NE1 1 
ATOM 349  C CE2 . TRP A 1 47  ? 363.355 368.505 499.169 1.00 79.51  ? 47  TRP H CE2 1 
ATOM 350  C CE3 . TRP A 1 47  ? 365.379 367.434 499.894 1.00 79.51  ? 47  TRP H CE3 1 
ATOM 351  C CZ2 . TRP A 1 47  ? 363.149 367.547 498.194 1.00 79.51  ? 47  TRP H CZ2 1 
ATOM 352  C CZ3 . TRP A 1 47  ? 365.170 366.490 498.926 1.00 79.51  ? 47  TRP H CZ3 1 
ATOM 353  C CH2 . TRP A 1 47  ? 364.065 366.549 498.090 1.00 79.51  ? 47  TRP H CH2 1 
ATOM 354  N N   . LEU A 1 48  ? 363.306 367.728 503.585 1.00 82.34  ? 48  LEU H N   1 
ATOM 355  C CA  . LEU A 1 48  ? 362.833 366.358 503.710 1.00 82.34  ? 48  LEU H CA  1 
ATOM 356  C C   . LEU A 1 48  ? 362.174 365.830 502.449 1.00 82.34  ? 48  LEU H C   1 
ATOM 357  O O   . LEU A 1 48  ? 362.361 364.663 502.107 1.00 82.34  ? 48  LEU H O   1 
ATOM 358  C CB  . LEU A 1 48  ? 361.859 366.246 504.882 1.00 82.34  ? 48  LEU H CB  1 
ATOM 359  C CG  . LEU A 1 48  ? 362.408 366.735 506.213 1.00 82.34  ? 48  LEU H CG  1 
ATOM 360  C CD1 . LEU A 1 48  ? 361.379 366.548 507.288 1.00 82.34  ? 48  LEU H CD1 1 
ATOM 361  C CD2 . LEU A 1 48  ? 363.661 365.982 506.554 1.00 82.34  ? 48  LEU H CD2 1 
ATOM 362  N N   . GLY A 1 49  ? 361.400 366.650 501.749 1.00 78.21  ? 49  GLY H N   1 
ATOM 363  C CA  . GLY A 1 49  ? 360.756 366.196 500.533 1.00 78.21  ? 49  GLY H CA  1 
ATOM 364  C C   . GLY A 1 49  ? 359.761 367.180 499.966 1.00 78.21  ? 49  GLY H C   1 
ATOM 365  O O   . GLY A 1 49  ? 359.440 368.165 500.627 1.00 78.21  ? 49  GLY H O   1 
ATOM 366  N N   . PHE A 1 50  ? 359.274 366.959 498.750 1.00 73.16  ? 50  PHE H N   1 
ATOM 367  C CA  . PHE A 1 50  ? 358.172 367.762 498.254 1.00 73.16  ? 50  PHE H CA  1 
ATOM 368  C C   . PHE A 1 50  ? 357.109 366.887 497.617 1.00 73.16  ? 50  PHE H C   1 
ATOM 369  O O   . PHE A 1 50  ? 357.165 365.659 497.654 1.00 73.16  ? 50  PHE H O   1 
ATOM 370  C CB  . PHE A 1 50  ? 358.613 368.866 497.272 1.00 73.16  ? 50  PHE H CB  1 
ATOM 371  C CG  . PHE A 1 50  ? 359.398 368.405 496.068 1.00 73.16  ? 50  PHE H CG  1 
ATOM 372  C CD1 . PHE A 1 50  ? 358.783 367.833 494.971 1.00 73.16  ? 50  PHE H CD1 1 
ATOM 373  C CD2 . PHE A 1 50  ? 360.741 368.672 495.987 1.00 73.16  ? 50  PHE H CD2 1 
ATOM 374  C CE1 . PHE A 1 50  ? 359.502 367.453 493.874 1.00 73.16  ? 50  PHE H CE1 1 
ATOM 375  C CE2 . PHE A 1 50  ? 361.463 368.300 494.888 1.00 73.16  ? 50  PHE H CE2 1 
ATOM 376  C CZ  . PHE A 1 50  ? 360.838 367.692 493.829 1.00 73.16  ? 50  PHE H CZ  1 
ATOM 377  N N   . LEU A 1 51  ? 356.136 367.559 497.018 1.00 73.28  ? 51  LEU H N   1 
ATOM 378  C CA  . LEU A 1 51  ? 355.010 366.925 496.356 1.00 73.28  ? 51  LEU H CA  1 
ATOM 379  C C   . LEU A 1 51  ? 354.565 367.822 495.214 1.00 73.28  ? 51  LEU H C   1 
ATOM 380  O O   . LEU A 1 51  ? 354.138 368.953 495.446 1.00 73.28  ? 51  LEU H O   1 
ATOM 381  C CB  . LEU A 1 51  ? 353.882 366.676 497.358 1.00 73.28  ? 51  LEU H CB  1 
ATOM 382  C CG  . LEU A 1 51  ? 352.607 365.959 496.944 1.00 73.28  ? 51  LEU H CG  1 
ATOM 383  C CD1 . LEU A 1 51  ? 352.183 365.066 498.059 1.00 73.28  ? 51  LEU H CD1 1 
ATOM 384  C CD2 . LEU A 1 51  ? 351.518 366.972 496.703 1.00 73.28  ? 51  LEU H CD2 1 
ATOM 385  N N   . ARG A 1 52  ? 354.653 367.312 493.993 1.00 69.30  ? 52  ARG H N   1 
ATOM 386  C CA  . ARG A 1 52  ? 354.452 368.095 492.787 1.00 69.30  ? 52  ARG H CA  1 
ATOM 387  C C   . ARG A 1 52  ? 352.980 368.455 492.598 1.00 69.30  ? 52  ARG H C   1 
ATOM 388  O O   . ARG A 1 52  ? 352.098 367.971 493.302 1.00 69.30  ? 52  ARG H O   1 
ATOM 389  C CB  . ARG A 1 52  ? 354.984 367.324 491.590 1.00 69.30  ? 52  ARG H CB  1 
ATOM 390  C CG  . ARG A 1 52  ? 356.189 366.505 491.954 1.00 69.30  ? 52  ARG H CG  1 
ATOM 391  C CD  . ARG A 1 52  ? 356.973 366.032 490.766 1.00 69.30  ? 52  ARG H CD  1 
ATOM 392  N NE  . ARG A 1 52  ? 357.978 365.065 491.187 1.00 69.30  ? 52  ARG H NE  1 
ATOM 393  C CZ  . ARG A 1 52  ? 358.967 364.633 490.422 1.00 69.30  ? 52  ARG H CZ  1 
ATOM 394  N NH1 . ARG A 1 52  ? 359.088 365.079 489.186 1.00 69.30  ? 52  ARG H NH1 1 
ATOM 395  N NH2 . ARG A 1 52  ? 359.833 363.754 490.890 1.00 69.30  ? 52  ARG H NH2 1 
ATOM 396  N N   . ASN A 1 53  ? 352.716 369.323 491.625 1.00 70.30  ? 53  ASN H N   1 
ATOM 397  C CA  . ASN A 1 53  ? 351.380 369.870 491.439 1.00 70.30  ? 53  ASN H CA  1 
ATOM 398  C C   . ASN A 1 53  ? 350.508 368.880 490.681 1.00 70.30  ? 53  ASN H C   1 
ATOM 399  O O   . ASN A 1 53  ? 350.912 367.750 490.403 1.00 70.30  ? 53  ASN H O   1 
ATOM 400  C CB  . ASN A 1 53  ? 351.450 371.215 490.731 1.00 70.30  ? 53  ASN H CB  1 
ATOM 401  C CG  . ASN A 1 53  ? 352.384 371.201 489.567 1.00 70.30  ? 53  ASN H CG  1 
ATOM 402  O OD1 . ASN A 1 53  ? 352.984 370.184 489.263 1.00 70.30  ? 53  ASN H OD1 1 
ATOM 403  N ND2 . ASN A 1 53  ? 352.519 372.332 488.902 1.00 70.30  ? 53  ASN H ND2 1 
ATOM 404  N N   . LYS A 1 54  ? 349.286 369.300 490.342 1.00 68.46  ? 54  LYS H N   1 
ATOM 405  C CA  . LYS A 1 54  ? 348.343 368.409 489.679 1.00 68.46  ? 54  LYS H CA  1 
ATOM 406  C C   . LYS A 1 54  ? 348.774 368.093 488.263 1.00 68.46  ? 54  LYS H C   1 
ATOM 407  O O   . LYS A 1 54  ? 348.533 366.986 487.777 1.00 68.46  ? 54  LYS H O   1 
ATOM 408  C CB  . LYS A 1 54  ? 346.949 369.023 489.659 1.00 68.46  ? 54  LYS H CB  1 
ATOM 409  C CG  . LYS A 1 54  ? 345.859 368.034 489.314 1.00 68.46  ? 54  LYS H CG  1 
ATOM 410  C CD  . LYS A 1 54  ? 344.472 368.615 489.480 1.00 68.46  ? 54  LYS H CD  1 
ATOM 411  C CE  . LYS A 1 54  ? 343.889 369.028 488.149 1.00 68.46  ? 54  LYS H CE  1 
ATOM 412  N NZ  . LYS A 1 54  ? 342.422 369.251 488.215 1.00 68.46  ? 54  LYS H NZ  1 
ATOM 413  N N   . ALA A 1 55  ? 349.437 369.029 487.603 1.00 63.10  ? 55  ALA H N   1 
ATOM 414  C CA  . ALA A 1 55  ? 349.842 368.831 486.225 1.00 63.10  ? 55  ALA H CA  1 
ATOM 415  C C   . ALA A 1 55  ? 351.016 367.885 486.083 1.00 63.10  ? 55  ALA H C   1 
ATOM 416  O O   . ALA A 1 55  ? 351.289 367.437 484.970 1.00 63.10  ? 55  ALA H O   1 
ATOM 417  C CB  . ALA A 1 55  ? 350.186 370.170 485.595 1.00 63.10  ? 55  ALA H CB  1 
ATOM 418  N N   . ASN A 1 56  ? 351.706 367.561 487.172 1.00 65.72  ? 56  ASN H N   1 
ATOM 419  C CA  . ASN A 1 56  ? 352.794 366.596 487.142 1.00 65.72  ? 56  ASN H CA  1 
ATOM 420  C C   . ASN A 1 56  ? 352.449 365.306 487.868 1.00 65.72  ? 56  ASN H C   1 
ATOM 421  O O   . ASN A 1 56  ? 353.295 364.412 487.955 1.00 65.72  ? 56  ASN H O   1 
ATOM 422  C CB  . ASN A 1 56  ? 354.058 367.214 487.727 1.00 65.72  ? 56  ASN H CB  1 
ATOM 423  C CG  . ASN A 1 56  ? 354.545 368.372 486.914 1.00 65.72  ? 56  ASN H CG  1 
ATOM 424  O OD1 . ASN A 1 56  ? 355.106 369.322 487.439 1.00 65.72  ? 56  ASN H OD1 1 
ATOM 425  N ND2 . ASN A 1 56  ? 354.318 368.309 485.618 1.00 65.72  ? 56  ASN H ND2 1 
ATOM 426  N N   . GLY A 1 57  ? 351.239 365.184 488.390 1.00 67.28  ? 57  GLY H N   1 
ATOM 427  C CA  . GLY A 1 57  ? 350.736 363.911 488.840 1.00 67.28  ? 57  GLY H CA  1 
ATOM 428  C C   . GLY A 1 57  ? 350.893 363.603 490.306 1.00 67.28  ? 57  GLY H C   1 
ATOM 429  O O   . GLY A 1 57  ? 350.763 362.432 490.678 1.00 67.28  ? 57  GLY H O   1 
ATOM 430  N N   . TYR A 1 58  ? 351.199 364.603 491.135 1.00 71.35  ? 58  TYR H N   1 
ATOM 431  C CA  . TYR A 1 58  ? 351.255 364.494 492.597 1.00 71.35  ? 58  TYR H CA  1 
ATOM 432  C C   . TYR A 1 58  ? 352.294 363.487 493.082 1.00 71.35  ? 58  TYR H C   1 
ATOM 433  O O   . TYR A 1 58  ? 352.153 362.922 494.163 1.00 71.35  ? 58  TYR H O   1 
ATOM 434  C CB  . TYR A 1 58  ? 349.891 364.140 493.193 1.00 71.35  ? 58  TYR H CB  1 
ATOM 435  C CG  . TYR A 1 58  ? 348.827 365.187 493.050 1.00 71.35  ? 58  TYR H CG  1 
ATOM 436  C CD1 . TYR A 1 58  ? 349.059 366.495 493.421 1.00 71.35  ? 58  TYR H CD1 1 
ATOM 437  C CD2 . TYR A 1 58  ? 347.581 364.855 492.556 1.00 71.35  ? 58  TYR H CD2 1 
ATOM 438  C CE1 . TYR A 1 58  ? 348.082 367.443 493.297 1.00 71.35  ? 58  TYR H CE1 1 
ATOM 439  C CE2 . TYR A 1 58  ? 346.604 365.791 492.429 1.00 71.35  ? 58  TYR H CE2 1 
ATOM 440  C CZ  . TYR A 1 58  ? 346.857 367.082 492.802 1.00 71.35  ? 58  TYR H CZ  1 
ATOM 441  O OH  . TYR A 1 58  ? 345.867 368.019 492.673 1.00 71.35  ? 58  TYR H OH  1 
ATOM 442  N N   . THR A 1 59  ? 353.338 363.242 492.301 1.00 71.49  ? 59  THR H N   1 
ATOM 443  C CA  . THR A 1 59  ? 354.385 362.338 492.736 1.00 71.49  ? 59  THR H CA  1 
ATOM 444  C C   . THR A 1 59  ? 355.214 362.991 493.833 1.00 71.49  ? 59  THR H C   1 
ATOM 445  O O   . THR A 1 59  ? 355.173 364.200 494.038 1.00 71.49  ? 59  THR H O   1 
ATOM 446  C CB  . THR A 1 59  ? 355.268 361.940 491.561 1.00 71.49  ? 59  THR H CB  1 
ATOM 447  O OG1 . THR A 1 59  ? 355.487 363.081 490.731 1.00 71.49  ? 59  THR H OG1 1 
ATOM 448  C CG2 . THR A 1 59  ? 354.607 360.862 490.740 1.00 71.49  ? 59  THR H CG2 1 
ATOM 449  N N   . THR A 1 60  ? 355.966 362.174 494.558 1.00 74.59  ? 60  THR H N   1 
ATOM 450  C CA  . THR A 1 60  ? 356.699 362.630 495.727 1.00 74.59  ? 60  THR H CA  1 
ATOM 451  C C   . THR A 1 60  ? 358.187 362.405 495.533 1.00 74.59  ? 60  THR H C   1 
ATOM 452  O O   . THR A 1 60  ? 358.601 361.570 494.731 1.00 74.59  ? 60  THR H O   1 
ATOM 453  C CB  . THR A 1 60  ? 356.236 361.906 496.984 1.00 74.59  ? 60  THR H CB  1 
ATOM 454  O OG1 . THR A 1 60  ? 356.388 360.498 496.796 1.00 74.59  ? 60  THR H OG1 1 
ATOM 455  C CG2 . THR A 1 60  ? 354.790 362.207 497.272 1.00 74.59  ? 60  THR H CG2 1 
ATOM 456  N N   . GLU A 1 61  ? 358.991 363.159 496.275 1.00 75.19  ? 61  GLU H N   1 
ATOM 457  C CA  . GLU A 1 61  ? 360.445 363.078 496.175 1.00 75.19  ? 61  GLU H CA  1 
ATOM 458  C C   . GLU A 1 61  ? 361.059 363.235 497.556 1.00 75.19  ? 61  GLU H C   1 
ATOM 459  O O   . GLU A 1 61  ? 361.369 364.352 497.965 1.00 75.19  ? 61  GLU H O   1 
ATOM 460  C CB  . GLU A 1 61  ? 360.981 364.142 495.240 1.00 75.19  ? 61  GLU H CB  1 
ATOM 461  C CG  . GLU A 1 61  ? 362.330 363.820 494.696 1.00 75.19  ? 61  GLU H CG  1 
ATOM 462  C CD  . GLU A 1 61  ? 362.247 362.826 493.580 1.00 75.19  ? 61  GLU H CD  1 
ATOM 463  O OE1 . GLU A 1 61  ? 362.838 361.738 493.703 1.00 75.19  ? 61  GLU H OE1 1 
ATOM 464  O OE2 . GLU A 1 61  ? 361.576 363.129 492.576 1.00 75.19  ? 61  GLU H OE2 1 
ATOM 465  N N   . TYR A 1 62  ? 361.287 362.129 498.250 1.00 81.34  ? 62  TYR H N   1 
ATOM 466  C CA  . TYR A 1 62  ? 361.809 362.207 499.600 1.00 81.34  ? 62  TYR H CA  1 
ATOM 467  C C   . TYR A 1 62  ? 363.317 362.405 499.588 1.00 81.34  ? 62  TYR H C   1 
ATOM 468  O O   . TYR A 1 62  ? 363.985 362.266 498.564 1.00 81.34  ? 62  TYR H O   1 
ATOM 469  C CB  . TYR A 1 62  ? 361.452 360.953 500.385 1.00 81.34  ? 62  TYR H CB  1 
ATOM 470  C CG  . TYR A 1 62  ? 359.988 360.654 500.351 1.00 81.34  ? 62  TYR H CG  1 
ATOM 471  C CD1 . TYR A 1 62  ? 359.107 361.349 501.153 1.00 81.34  ? 62  TYR H CD1 1 
ATOM 472  C CD2 . TYR A 1 62  ? 359.482 359.689 499.502 1.00 81.34  ? 62  TYR H CD2 1 
ATOM 473  C CE1 . TYR A 1 62  ? 357.766 361.086 501.117 1.00 81.34  ? 62  TYR H CE1 1 
ATOM 474  C CE2 . TYR A 1 62  ? 358.142 359.420 499.459 1.00 81.34  ? 62  TYR H CE2 1 
ATOM 475  C CZ  . TYR A 1 62  ? 357.290 360.122 500.269 1.00 81.34  ? 62  TYR H CZ  1 
ATOM 476  O OH  . TYR A 1 62  ? 355.947 359.855 500.232 1.00 81.34  ? 62  TYR H OH  1 
ATOM 477  N N   . SER A 1 63  ? 363.849 362.746 500.752 1.00 85.18  ? 63  SER H N   1 
ATOM 478  C CA  . SER A 1 63  ? 365.285 362.840 500.941 1.00 85.18  ? 63  SER H CA  1 
ATOM 479  C C   . SER A 1 63  ? 365.825 361.434 501.148 1.00 85.18  ? 63  SER H C   1 
ATOM 480  O O   . SER A 1 63  ? 365.075 360.493 501.408 1.00 85.18  ? 63  SER H O   1 
ATOM 481  C CB  . SER A 1 63  ? 365.605 363.763 502.110 1.00 85.18  ? 63  SER H CB  1 
ATOM 482  O OG  . SER A 1 63  ? 366.999 363.908 502.280 1.00 85.18  ? 63  SER H OG  1 
ATOM 483  N N   . ALA A 1 64  ? 367.136 361.266 501.046 1.00 88.85  ? 64  ALA H N   1 
ATOM 484  C CA  . ALA A 1 64  ? 367.712 359.942 501.221 1.00 88.85  ? 64  ALA H CA  1 
ATOM 485  C C   . ALA A 1 64  ? 367.792 359.541 502.686 1.00 88.85  ? 64  ALA H C   1 
ATOM 486  O O   . ALA A 1 64  ? 367.904 358.352 502.998 1.00 88.85  ? 64  ALA H O   1 
ATOM 487  C CB  . ALA A 1 64  ? 369.100 359.885 500.588 1.00 88.85  ? 64  ALA H CB  1 
ATOM 488  N N   . SER A 1 65  ? 367.728 360.510 503.595 1.00 91.04  ? 65  SER H N   1 
ATOM 489  C CA  . SER A 1 65  ? 367.820 360.193 505.011 1.00 91.04  ? 65  SER H CA  1 
ATOM 490  C C   . SER A 1 65  ? 366.516 359.639 505.569 1.00 91.04  ? 65  SER H C   1 
ATOM 491  O O   . SER A 1 65  ? 366.548 358.799 506.472 1.00 91.04  ? 65  SER H O   1 
ATOM 492  C CB  . SER A 1 65  ? 368.239 361.433 505.798 1.00 91.04  ? 65  SER H CB  1 
ATOM 493  O OG  . SER A 1 65  ? 367.369 362.514 505.535 1.00 91.04  ? 65  SER H OG  1 
ATOM 494  N N   . VAL A 1 66  ? 365.370 360.084 505.058 1.00 92.76  ? 66  VAL H N   1 
ATOM 495  C CA  . VAL A 1 66  ? 364.080 359.722 505.626 1.00 92.76  ? 66  VAL H CA  1 
ATOM 496  C C   . VAL A 1 66  ? 363.270 358.833 504.694 1.00 92.76  ? 66  VAL H C   1 
ATOM 497  O O   . VAL A 1 66  ? 362.094 358.571 504.966 1.00 92.76  ? 66  VAL H O   1 
ATOM 498  C CB  . VAL A 1 66  ? 363.275 360.969 506.020 1.00 92.76  ? 66  VAL H CB  1 
ATOM 499  C CG1 . VAL A 1 66  ? 364.087 361.850 506.932 1.00 92.76  ? 66  VAL H CG1 1 
ATOM 500  C CG2 . VAL A 1 66  ? 362.868 361.737 504.792 1.00 92.76  ? 66  VAL H CG2 1 
ATOM 501  N N   . LYS A 1 67  ? 363.871 358.348 503.613 1.00 92.16  ? 67  LYS H N   1 
ATOM 502  C CA  . LYS A 1 67  ? 363.146 357.562 502.621 1.00 92.16  ? 67  LYS H CA  1 
ATOM 503  C C   . LYS A 1 67  ? 362.764 356.209 503.200 1.00 92.16  ? 67  LYS H C   1 
ATOM 504  O O   . LYS A 1 67  ? 363.618 355.477 503.708 1.00 92.16  ? 67  LYS H O   1 
ATOM 505  C CB  . LYS A 1 67  ? 363.997 357.388 501.369 1.00 92.16  ? 67  LYS H CB  1 
ATOM 506  C CG  . LYS A 1 67  ? 363.582 356.251 500.462 1.00 92.16  ? 67  LYS H CG  1 
ATOM 507  C CD  . LYS A 1 67  ? 362.594 356.687 499.408 1.00 92.16  ? 67  LYS H CD  1 
ATOM 508  C CE  . LYS A 1 67  ? 362.532 355.659 498.299 1.00 92.16  ? 67  LYS H CE  1 
ATOM 509  N NZ  . LYS A 1 67  ? 361.488 355.956 497.293 1.00 92.16  ? 67  LYS H NZ  1 
ATOM 510  N N   . GLY A 1 68  ? 361.478 355.886 503.132 1.00 97.26  ? 68  GLY H N   1 
ATOM 511  C CA  . GLY A 1 68  ? 360.945 354.672 503.693 1.00 97.26  ? 68  GLY H CA  1 
ATOM 512  C C   . GLY A 1 68  ? 360.230 354.864 505.008 1.00 97.26  ? 68  GLY H C   1 
ATOM 513  O O   . GLY A 1 68  ? 359.346 354.070 505.336 1.00 97.26  ? 68  GLY H O   1 
ATOM 514  N N   . ARG A 1 69  ? 360.583 355.901 505.761 1.00 101.37 ? 69  ARG H N   1 
ATOM 515  C CA  . ARG A 1 69  ? 359.948 356.173 507.043 1.00 101.37 ? 69  ARG H CA  1 
ATOM 516  C C   . ARG A 1 69  ? 358.817 357.179 506.928 1.00 101.37 ? 69  ARG H C   1 
ATOM 517  O O   . ARG A 1 69  ? 357.699 356.900 507.372 1.00 101.37 ? 69  ARG H O   1 
ATOM 518  C CB  . ARG A 1 69  ? 360.980 356.688 508.043 1.00 101.37 ? 69  ARG H CB  1 
ATOM 519  C CG  . ARG A 1 69  ? 362.033 355.681 508.393 1.00 101.37 ? 69  ARG H CG  1 
ATOM 520  C CD  . ARG A 1 69  ? 362.699 356.035 509.693 1.00 101.37 ? 69  ARG H CD  1 
ATOM 521  N NE  . ARG A 1 69  ? 363.720 357.062 509.530 1.00 101.37 ? 69  ARG H NE  1 
ATOM 522  C CZ  . ARG A 1 69  ? 363.628 358.295 510.013 1.00 101.37 ? 69  ARG H CZ  1 
ATOM 523  N NH1 . ARG A 1 69  ? 362.557 358.667 510.692 1.00 101.37 ? 69  ARG H NH1 1 
ATOM 524  N NH2 . ARG A 1 69  ? 364.616 359.156 509.817 1.00 101.37 ? 69  ARG H NH2 1 
ATOM 525  N N   . PHE A 1 70  ? 359.082 358.337 506.334 1.00 99.13  ? 70  PHE H N   1 
ATOM 526  C CA  . PHE A 1 70  ? 358.120 359.428 506.290 1.00 99.13  ? 70  PHE H CA  1 
ATOM 527  C C   . PHE A 1 70  ? 357.258 359.292 505.045 1.00 99.13  ? 70  PHE H C   1 
ATOM 528  O O   . PHE A 1 70  ? 357.586 358.558 504.113 1.00 99.13  ? 70  PHE H O   1 
ATOM 529  C CB  . PHE A 1 70  ? 358.808 360.796 506.273 1.00 99.13  ? 70  PHE H CB  1 
ATOM 530  C CG  . PHE A 1 70  ? 359.478 361.195 507.571 1.00 99.13  ? 70  PHE H CG  1 
ATOM 531  C CD1 . PHE A 1 70  ? 359.508 360.362 508.677 1.00 99.13  ? 70  PHE H CD1 1 
ATOM 532  C CD2 . PHE A 1 70  ? 360.084 362.435 507.668 1.00 99.13  ? 70  PHE H CD2 1 
ATOM 533  C CE1 . PHE A 1 70  ? 360.142 360.748 509.830 1.00 99.13  ? 70  PHE H CE1 1 
ATOM 534  C CE2 . PHE A 1 70  ? 360.707 362.831 508.825 1.00 99.13  ? 70  PHE H CE2 1 
ATOM 535  C CZ  . PHE A 1 70  ? 360.737 361.990 509.905 1.00 99.13  ? 70  PHE H CZ  1 
ATOM 536  N N   . THR A 1 71  ? 356.148 360.019 505.030 1.00 94.60  ? 71  THR H N   1 
ATOM 537  C CA  . THR A 1 71  ? 355.240 359.971 503.891 1.00 94.60  ? 71  THR H CA  1 
ATOM 538  C C   . THR A 1 71  ? 354.564 361.321 503.751 1.00 94.60  ? 71  THR H C   1 
ATOM 539  O O   . THR A 1 71  ? 353.958 361.810 504.706 1.00 94.60  ? 71  THR H O   1 
ATOM 540  C CB  . THR A 1 71  ? 354.196 358.866 504.061 1.00 94.60  ? 71  THR H CB  1 
ATOM 541  O OG1 . THR A 1 71  ? 354.841 357.588 504.062 1.00 94.60  ? 71  THR H OG1 1 
ATOM 542  C CG2 . THR A 1 71  ? 353.185 358.904 502.929 1.00 94.60  ? 71  THR H CG2 1 
ATOM 543  N N   . ILE A 1 72  ? 354.672 361.919 502.571 1.00 87.99  ? 72  ILE H N   1 
ATOM 544  C CA  . ILE A 1 72  ? 353.975 363.150 502.233 1.00 87.99  ? 72  ILE H CA  1 
ATOM 545  C C   . ILE A 1 72  ? 352.753 362.781 501.410 1.00 87.99  ? 72  ILE H C   1 
ATOM 546  O O   . ILE A 1 72  ? 352.811 361.866 500.582 1.00 87.99  ? 72  ILE H O   1 
ATOM 547  C CB  . ILE A 1 72  ? 354.891 364.113 501.465 1.00 87.99  ? 72  ILE H CB  1 
ATOM 548  C CG1 . ILE A 1 72  ? 356.255 364.165 502.135 1.00 87.99  ? 72  ILE H CG1 1 
ATOM 549  C CG2 . ILE A 1 72  ? 354.293 365.498 501.409 1.00 87.99  ? 72  ILE H CG2 1 
ATOM 550  C CD1 . ILE A 1 72  ? 357.214 365.111 501.478 1.00 87.99  ? 72  ILE H CD1 1 
ATOM 551  N N   . SER A 1 73  ? 351.647 363.476 501.645 1.00 91.44  ? 73  SER H N   1 
ATOM 552  C CA  . SER A 1 73  ? 350.421 363.227 500.907 1.00 91.44  ? 73  SER H CA  1 
ATOM 553  C C   . SER A 1 73  ? 349.576 364.486 500.938 1.00 91.44  ? 73  SER H C   1 
ATOM 554  O O   . SER A 1 73  ? 350.006 365.538 501.410 1.00 91.44  ? 73  SER H O   1 
ATOM 555  C CB  . SER A 1 73  ? 349.643 362.048 501.487 1.00 91.44  ? 73  SER H CB  1 
ATOM 556  O OG  . SER A 1 73  ? 348.349 361.974 500.919 1.00 91.44  ? 73  SER H OG  1 
ATOM 557  N N   . ARG A 1 74  ? 348.359 364.358 500.434 1.00 93.18  ? 74  ARG H N   1 
ATOM 558  C CA  . ARG A 1 74  ? 347.399 365.444 500.411 1.00 93.18  ? 74  ARG H CA  1 
ATOM 559  C C   . ARG A 1 74  ? 346.001 364.867 500.538 1.00 93.18  ? 74  ARG H C   1 
ATOM 560  O O   . ARG A 1 74  ? 345.771 363.684 500.278 1.00 93.18  ? 74  ARG H O   1 
ATOM 561  C CB  . ARG A 1 74  ? 347.512 366.249 499.124 1.00 93.18  ? 74  ARG H CB  1 
ATOM 562  C CG  . ARG A 1 74  ? 347.306 365.410 497.891 1.00 93.18  ? 74  ARG H CG  1 
ATOM 563  C CD  . ARG A 1 74  ? 347.313 366.256 496.655 1.00 93.18  ? 74  ARG H CD  1 
ATOM 564  N NE  . ARG A 1 74  ? 346.337 367.334 496.730 1.00 93.18  ? 74  ARG H NE  1 
ATOM 565  C CZ  . ARG A 1 74  ? 345.064 367.210 496.377 1.00 93.18  ? 74  ARG H CZ  1 
ATOM 566  N NH1 . ARG A 1 74  ? 344.608 366.050 495.926 1.00 93.18  ? 74  ARG H NH1 1 
ATOM 567  N NH2 . ARG A 1 74  ? 344.245 368.246 496.475 1.00 93.18  ? 74  ARG H NH2 1 
ATOM 568  N N   . ASP A 1 75  ? 345.061 365.713 500.935 1.00 102.21 ? 75  ASP H N   1 
ATOM 569  C CA  . ASP A 1 75  ? 343.660 365.333 500.976 1.00 102.21 ? 75  ASP H CA  1 
ATOM 570  C C   . ASP A 1 75  ? 342.984 365.827 499.708 1.00 102.21 ? 75  ASP H C   1 
ATOM 571  O O   . ASP A 1 75  ? 343.181 366.971 499.293 1.00 102.21 ? 75  ASP H O   1 
ATOM 572  C CB  . ASP A 1 75  ? 342.961 365.916 502.200 1.00 102.21 ? 75  ASP H CB  1 
ATOM 573  C CG  . ASP A 1 75  ? 341.559 365.369 502.386 1.00 102.21 ? 75  ASP H CG  1 
ATOM 574  O OD1 . ASP A 1 75  ? 341.202 364.371 501.721 1.00 102.21 ? 75  ASP H OD1 1 
ATOM 575  O OD2 . ASP A 1 75  ? 340.805 365.944 503.198 1.00 102.21 ? 75  ASP H OD2 1 
ATOM 576  N N   . ASN A 1 76  ? 342.185 364.957 499.095 1.00 105.02 ? 76  ASN H N   1 
ATOM 577  C CA  . ASN A 1 76  ? 341.552 365.303 497.831 1.00 105.02 ? 76  ASN H CA  1 
ATOM 578  C C   . ASN A 1 76  ? 340.309 366.165 498.011 1.00 105.02 ? 76  ASN H C   1 
ATOM 579  O O   . ASN A 1 76  ? 339.841 366.778 497.046 1.00 105.02 ? 76  ASN H O   1 
ATOM 580  C CB  . ASN A 1 76  ? 341.218 364.032 497.056 1.00 105.02 ? 76  ASN H CB  1 
ATOM 581  C CG  . ASN A 1 76  ? 340.459 363.022 497.888 1.00 105.02 ? 76  ASN H CG  1 
ATOM 582  O OD1 . ASN A 1 76  ? 340.142 363.265 499.052 1.00 105.02 ? 76  ASN H OD1 1 
ATOM 583  N ND2 . ASN A 1 76  ? 340.162 361.874 497.292 1.00 105.02 ? 76  ASN H ND2 1 
ATOM 584  N N   . SER A 1 77  ? 339.760 366.227 499.223 1.00 105.47 ? 77  SER H N   1 
ATOM 585  C CA  . SER A 1 77  ? 338.582 367.052 499.453 1.00 105.47 ? 77  SER H CA  1 
ATOM 586  C C   . SER A 1 77  ? 338.963 368.520 499.597 1.00 105.47 ? 77  SER H C   1 
ATOM 587  O O   . SER A 1 77  ? 338.580 369.356 498.774 1.00 105.47 ? 77  SER H O   1 
ATOM 588  C CB  . SER A 1 77  ? 337.840 366.569 500.700 1.00 105.47 ? 77  SER H CB  1 
ATOM 589  O OG  . SER A 1 77  ? 337.377 365.243 500.543 1.00 105.47 ? 77  SER H OG  1 
ATOM 590  N N   . GLN A 1 78  ? 339.735 368.844 500.626 1.00 102.57 ? 78  GLN H N   1 
ATOM 591  C CA  . GLN A 1 78  ? 340.120 370.213 500.925 1.00 102.57 ? 78  GLN H CA  1 
ATOM 592  C C   . GLN A 1 78  ? 341.625 370.387 500.799 1.00 102.57 ? 78  GLN H C   1 
ATOM 593  O O   . GLN A 1 78  ? 342.369 369.442 500.535 1.00 102.57 ? 78  GLN H O   1 
ATOM 594  C CB  . GLN A 1 78  ? 339.658 370.614 502.325 1.00 102.57 ? 78  GLN H CB  1 
ATOM 595  C CG  . GLN A 1 78  ? 340.057 369.635 503.397 1.00 102.57 ? 78  GLN H CG  1 
ATOM 596  C CD  . GLN A 1 78  ? 338.877 368.838 503.893 1.00 102.57 ? 78  GLN H CD  1 
ATOM 597  O OE1 . GLN A 1 78  ? 337.813 368.850 503.281 1.00 102.57 ? 78  GLN H OE1 1 
ATOM 598  N NE2 . GLN A 1 78  ? 339.050 368.153 505.013 1.00 102.57 ? 78  GLN H NE2 1 
ATOM 599  N N   . SER A 1 79  ? 342.068 371.625 500.999 1.00 98.03  ? 79  SER H N   1 
ATOM 600  C CA  . SER A 1 79  ? 343.463 372.002 500.783 1.00 98.03  ? 79  SER H CA  1 
ATOM 601  C C   . SER A 1 79  ? 344.236 371.796 502.075 1.00 98.03  ? 79  SER H C   1 
ATOM 602  O O   . SER A 1 79  ? 344.553 372.743 502.791 1.00 98.03  ? 79  SER H O   1 
ATOM 603  C CB  . SER A 1 79  ? 343.553 373.444 500.314 1.00 98.03  ? 79  SER H CB  1 
ATOM 604  O OG  . SER A 1 79  ? 343.413 374.322 501.413 1.00 98.03  ? 79  SER H OG  1 
ATOM 605  N N   . ILE A 1 80  ? 344.546 370.535 502.378 1.00 96.70  ? 80  ILE H N   1 
ATOM 606  C CA  . ILE A 1 80  ? 345.299 370.175 503.573 1.00 96.70  ? 80  ILE H CA  1 
ATOM 607  C C   . ILE A 1 80  ? 346.439 369.262 503.153 1.00 96.70  ? 80  ILE H C   1 
ATOM 608  O O   . ILE A 1 80  ? 346.235 368.251 502.482 1.00 96.70  ? 80  ILE H O   1 
ATOM 609  C CB  . ILE A 1 80  ? 344.410 369.482 504.635 1.00 96.70  ? 80  ILE H CB  1 
ATOM 610  C CG1 . ILE A 1 80  ? 343.310 370.429 505.127 1.00 96.70  ? 80  ILE H CG1 1 
ATOM 611  C CG2 . ILE A 1 80  ? 345.254 368.985 505.793 1.00 96.70  ? 80  ILE H CG2 1 
ATOM 612  C CD1 . ILE A 1 80  ? 342.575 369.962 506.366 1.00 96.70  ? 80  ILE H CD1 1 
ATOM 613  N N   . LEU A 1 81  ? 347.655 369.627 503.547 1.00 92.41  ? 81  LEU H N   1 
ATOM 614  C CA  . LEU A 1 81  ? 348.843 368.844 503.249 1.00 92.41  ? 81  LEU H CA  1 
ATOM 615  C C   . LEU A 1 81  ? 349.254 368.083 504.496 1.00 92.41  ? 81  LEU H C   1 
ATOM 616  O O   . LEU A 1 81  ? 349.238 368.638 505.596 1.00 92.41  ? 81  LEU H O   1 
ATOM 617  C CB  . LEU A 1 81  ? 349.986 369.735 502.782 1.00 92.41  ? 81  LEU H CB  1 
ATOM 618  C CG  . LEU A 1 81  ? 351.215 369.062 502.186 1.00 92.41  ? 81  LEU H CG  1 
ATOM 619  C CD1 . LEU A 1 81  ? 350.989 368.801 500.725 1.00 92.41  ? 81  LEU H CD1 1 
ATOM 620  C CD2 . LEU A 1 81  ? 352.424 369.938 502.379 1.00 92.41  ? 81  LEU H CD2 1 
ATOM 621  N N   . TYR A 1 82  ? 349.627 366.820 504.323 1.00 94.86  ? 82  TYR H N   1 
ATOM 622  C CA  . TYR A 1 82  ? 349.890 365.907 505.425 1.00 94.86  ? 82  TYR H CA  1 
ATOM 623  C C   . TYR A 1 82  ? 351.358 365.519 505.467 1.00 94.86  ? 82  TYR H C   1 
ATOM 624  O O   . TYR A 1 82  ? 352.092 365.661 504.492 1.00 94.86  ? 82  TYR H O   1 
ATOM 625  C CB  . TYR A 1 82  ? 349.043 364.638 505.301 1.00 94.86  ? 82  TYR H CB  1 
ATOM 626  C CG  . TYR A 1 82  ? 347.579 364.845 505.545 1.00 94.86  ? 82  TYR H CG  1 
ATOM 627  C CD1 . TYR A 1 82  ? 347.127 365.330 506.754 1.00 94.86  ? 82  TYR H CD1 1 
ATOM 628  C CD2 . TYR A 1 82  ? 346.650 364.554 504.563 1.00 94.86  ? 82  TYR H CD2 1 
ATOM 629  C CE1 . TYR A 1 82  ? 345.784 365.519 506.985 1.00 94.86  ? 82  TYR H CE1 1 
ATOM 630  C CE2 . TYR A 1 82  ? 345.307 364.740 504.780 1.00 94.86  ? 82  TYR H CE2 1 
ATOM 631  C CZ  . TYR A 1 82  ? 344.878 365.222 505.993 1.00 94.86  ? 82  TYR H CZ  1 
ATOM 632  O OH  . TYR A 1 82  ? 343.536 365.411 506.218 1.00 94.86  ? 82  TYR H OH  1 
ATOM 633  N N   . LEU A 1 83  ? 351.771 365.000 506.620 1.00 96.86  ? 83  LEU H N   1 
ATOM 634  C CA  . LEU A 1 83  ? 353.092 364.394 506.763 1.00 96.86  ? 83  LEU H CA  1 
ATOM 635  C C   . LEU A 1 83  ? 352.975 363.286 507.799 1.00 96.86  ? 83  LEU H C   1 
ATOM 636  O O   . LEU A 1 83  ? 352.841 363.571 508.991 1.00 96.86  ? 83  LEU H O   1 
ATOM 637  C CB  . LEU A 1 83  ? 354.131 365.417 507.179 1.00 96.86  ? 83  LEU H CB  1 
ATOM 638  C CG  . LEU A 1 83  ? 355.490 364.799 507.479 1.00 96.86  ? 83  LEU H CG  1 
ATOM 639  C CD1 . LEU A 1 83  ? 356.087 364.257 506.214 1.00 96.86  ? 83  LEU H CD1 1 
ATOM 640  C CD2 . LEU A 1 83  ? 356.411 365.807 508.108 1.00 96.86  ? 83  LEU H CD2 1 
ATOM 641  N N   . GLN A 1 84  ? 353.005 362.039 507.349 1.00 101.93 ? 84  GLN H N   1 
ATOM 642  C CA  . GLN A 1 84  ? 352.945 360.891 508.238 1.00 101.93 ? 84  GLN H CA  1 
ATOM 643  C C   . GLN A 1 84  ? 354.361 360.522 508.648 1.00 101.93 ? 84  GLN H C   1 
ATOM 644  O O   . GLN A 1 84  ? 355.129 360.002 507.836 1.00 101.93 ? 84  GLN H O   1 
ATOM 645  C CB  . GLN A 1 84  ? 352.256 359.709 507.564 1.00 101.93 ? 84  GLN H CB  1 
ATOM 646  C CG  . GLN A 1 84  ? 352.185 358.474 508.435 1.00 101.93 ? 84  GLN H CG  1 
ATOM 647  C CD  . GLN A 1 84  ? 351.041 358.522 509.421 1.00 101.93 ? 84  GLN H CD  1 
ATOM 648  O OE1 . GLN A 1 84  ? 349.887 358.676 509.035 1.00 101.93 ? 84  GLN H OE1 1 
ATOM 649  N NE2 . GLN A 1 84  ? 351.356 358.395 510.702 1.00 101.93 ? 84  GLN H NE2 1 
ATOM 650  N N   . MET A 1 85  ? 354.703 360.793 509.895 1.00 107.72 ? 85  MET H N   1 
ATOM 651  C CA  . MET A 1 85  ? 356.011 360.458 510.427 1.00 107.72 ? 85  MET H CA  1 
ATOM 652  C C   . MET A 1 85  ? 355.925 359.135 511.173 1.00 107.72 ? 85  MET H C   1 
ATOM 653  O O   . MET A 1 85  ? 355.136 358.982 512.107 1.00 107.72 ? 85  MET H O   1 
ATOM 654  C CB  . MET A 1 85  ? 356.504 361.550 511.376 1.00 107.72 ? 85  MET H CB  1 
ATOM 655  C CG  . MET A 1 85  ? 357.299 362.649 510.715 1.00 107.72 ? 85  MET H CG  1 
ATOM 656  S SD  . MET A 1 85  ? 358.040 363.748 511.922 1.00 107.72 ? 85  MET H SD  1 
ATOM 657  C CE  . MET A 1 85  ? 356.572 364.377 512.712 1.00 107.72 ? 85  MET H CE  1 
ATOM 658  N N   . ASN A 1 86  ? 356.746 358.178 510.758 1.00 109.49 ? 86  ASN H N   1 
ATOM 659  C CA  . ASN A 1 86  ? 356.762 356.864 511.378 1.00 109.49 ? 86  ASN H CA  1 
ATOM 660  C C   . ASN A 1 86  ? 358.177 356.546 511.824 1.00 109.49 ? 86  ASN H C   1 
ATOM 661  O O   . ASN A 1 86  ? 359.141 357.085 511.274 1.00 109.49 ? 86  ASN H O   1 
ATOM 662  C CB  . ASN A 1 86  ? 356.266 355.775 510.427 1.00 109.49 ? 86  ASN H CB  1 
ATOM 663  C CG  . ASN A 1 86  ? 354.768 355.786 510.266 1.00 109.49 ? 86  ASN H CG  1 
ATOM 664  O OD1 . ASN A 1 86  ? 354.250 355.976 509.169 1.00 109.49 ? 86  ASN H OD1 1 
ATOM 665  N ND2 . ASN A 1 86  ? 354.060 355.574 511.362 1.00 109.49 ? 86  ASN H ND2 1 
ATOM 666  N N   . ALA A 1 87  ? 358.277 355.666 512.826 1.00 109.73 ? 87  ALA H N   1 
ATOM 667  C CA  . ALA A 1 87  ? 359.536 355.179 513.396 1.00 109.73 ? 87  ALA H CA  1 
ATOM 668  C C   . ALA A 1 87  ? 360.424 356.331 513.863 1.00 109.73 ? 87  ALA H C   1 
ATOM 669  O O   . ALA A 1 87  ? 361.518 356.555 513.349 1.00 109.73 ? 87  ALA H O   1 
ATOM 670  C CB  . ALA A 1 87  ? 360.280 354.275 512.408 1.00 109.73 ? 87  ALA H CB  1 
ATOM 671  N N   . LEU A 1 88  ? 359.918 357.072 514.843 1.00 112.14 ? 88  LEU H N   1 
ATOM 672  C CA  . LEU A 1 88  ? 360.630 358.241 515.332 1.00 112.14 ? 88  LEU H CA  1 
ATOM 673  C C   . LEU A 1 88  ? 361.847 357.828 516.146 1.00 112.14 ? 88  LEU H C   1 
ATOM 674  O O   . LEU A 1 88  ? 361.838 356.805 516.834 1.00 112.14 ? 88  LEU H O   1 
ATOM 675  C CB  . LEU A 1 88  ? 359.716 359.119 516.182 1.00 112.14 ? 88  LEU H CB  1 
ATOM 676  C CG  . LEU A 1 88  ? 358.868 360.187 515.486 1.00 112.14 ? 88  LEU H CG  1 
ATOM 677  C CD1 . LEU A 1 88  ? 359.768 361.119 514.719 1.00 112.14 ? 88  LEU H CD1 1 
ATOM 678  C CD2 . LEU A 1 88  ? 357.780 359.630 514.588 1.00 112.14 ? 88  LEU H CD2 1 
ATOM 679  N N   . ARG A 1 89  ? 362.899 358.629 516.055 1.00 111.86 ? 89  ARG H N   1 
ATOM 680  C CA  . ARG A 1 89  ? 364.154 358.389 516.745 1.00 111.86 ? 89  ARG H CA  1 
ATOM 681  C C   . ARG A 1 89  ? 364.451 359.538 517.697 1.00 111.86 ? 89  ARG H C   1 
ATOM 682  O O   . ARG A 1 89  ? 363.608 360.395 517.969 1.00 111.86 ? 89  ARG H O   1 
ATOM 683  C CB  . ARG A 1 89  ? 365.297 358.208 515.751 1.00 111.86 ? 89  ARG H CB  1 
ATOM 684  C CG  . ARG A 1 89  ? 365.020 357.211 514.659 1.00 111.86 ? 89  ARG H CG  1 
ATOM 685  C CD  . ARG A 1 89  ? 366.174 357.188 513.680 1.00 111.86 ? 89  ARG H CD  1 
ATOM 686  N NE  . ARG A 1 89  ? 365.853 356.464 512.458 1.00 111.86 ? 89  ARG H NE  1 
ATOM 687  C CZ  . ARG A 1 89  ? 366.682 356.357 511.429 1.00 111.86 ? 89  ARG H CZ  1 
ATOM 688  N NH1 . ARG A 1 89  ? 367.877 356.926 511.483 1.00 111.86 ? 89  ARG H NH1 1 
ATOM 689  N NH2 . ARG A 1 89  ? 366.322 355.679 510.351 1.00 111.86 ? 89  ARG H NH2 1 
ATOM 690  N N   . ALA A 1 90  ? 365.674 359.534 518.222 1.00 112.79 ? 90  ALA H N   1 
ATOM 691  C CA  . ALA A 1 90  ? 366.095 360.564 519.157 1.00 112.79 ? 90  ALA H CA  1 
ATOM 692  C C   . ALA A 1 90  ? 366.502 361.854 518.469 1.00 112.79 ? 90  ALA H C   1 
ATOM 693  O O   . ALA A 1 90  ? 366.429 362.917 519.090 1.00 112.79 ? 90  ALA H O   1 
ATOM 694  C CB  . ALA A 1 90  ? 367.258 360.059 520.007 1.00 112.79 ? 90  ALA H CB  1 
ATOM 695  N N   . GLU A 1 91  ? 366.928 361.791 517.213 1.00 111.81 ? 91  GLU H N   1 
ATOM 696  C CA  . GLU A 1 91  ? 367.419 362.975 516.525 1.00 111.81 ? 91  GLU H CA  1 
ATOM 697  C C   . GLU A 1 91  ? 366.398 363.593 515.582 1.00 111.81 ? 91  GLU H C   1 
ATOM 698  O O   . GLU A 1 91  ? 366.778 364.388 514.718 1.00 111.81 ? 91  GLU H O   1 
ATOM 699  C CB  . GLU A 1 91  ? 368.703 362.648 515.756 1.00 111.81 ? 91  GLU H CB  1 
ATOM 700  C CG  . GLU A 1 91  ? 369.932 362.289 516.613 1.00 111.81 ? 91  GLU H CG  1 
ATOM 701  C CD  . GLU A 1 91  ? 370.551 363.431 517.434 1.00 111.81 ? 91  GLU H CD  1 
ATOM 702  O OE1 . GLU A 1 91  ? 371.692 363.237 517.899 1.00 111.81 ? 91  GLU H OE1 1 
ATOM 703  O OE2 . GLU A 1 91  ? 369.964 364.520 517.604 1.00 111.81 ? 91  GLU H OE2 1 
ATOM 704  N N   . ASP A 1 92  ? 365.125 363.252 515.717 1.00 108.81 ? 92  ASP H N   1 
ATOM 705  C CA  . ASP A 1 92  ? 364.083 363.888 514.933 1.00 108.81 ? 92  ASP H CA  1 
ATOM 706  C C   . ASP A 1 92  ? 363.448 365.064 515.657 1.00 108.81 ? 92  ASP H C   1 
ATOM 707  O O   . ASP A 1 92  ? 362.455 365.614 515.174 1.00 108.81 ? 92  ASP H O   1 
ATOM 708  C CB  . ASP A 1 92  ? 363.013 362.867 514.566 1.00 108.81 ? 92  ASP H CB  1 
ATOM 709  C CG  . ASP A 1 92  ? 363.547 361.770 513.687 1.00 108.81 ? 92  ASP H CG  1 
ATOM 710  O OD1 . ASP A 1 92  ? 364.573 362.001 513.018 1.00 108.81 ? 92  ASP H OD1 1 
ATOM 711  O OD2 . ASP A 1 92  ? 362.936 360.685 513.645 1.00 108.81 ? 92  ASP H OD2 1 
ATOM 712  N N   . SER A 1 93  ? 363.994 365.457 516.801 1.00 109.17 ? 93  SER H N   1 
ATOM 713  C CA  . SER A 1 93  ? 363.423 366.529 517.604 1.00 109.17 ? 93  SER H CA  1 
ATOM 714  C C   . SER A 1 93  ? 363.802 367.863 516.979 1.00 109.17 ? 93  SER H C   1 
ATOM 715  O O   . SER A 1 93  ? 364.938 368.319 517.126 1.00 109.17 ? 93  SER H O   1 
ATOM 716  C CB  . SER A 1 93  ? 363.923 366.432 519.039 1.00 109.17 ? 93  SER H CB  1 
ATOM 717  O OG  . SER A 1 93  ? 363.245 365.409 519.745 1.00 109.17 ? 93  SER H OG  1 
ATOM 718  N N   . ALA A 1 94  ? 362.857 368.496 516.291 1.00 103.54 ? 94  ALA H N   1 
ATOM 719  C CA  . ALA A 1 94  ? 363.159 369.695 515.521 1.00 103.54 ? 94  ALA H CA  1 
ATOM 720  C C   . ALA A 1 94  ? 361.895 370.535 515.380 1.00 103.54 ? 94  ALA H C   1 
ATOM 721  O O   . ALA A 1 94  ? 360.853 370.231 515.965 1.00 103.54 ? 94  ALA H O   1 
ATOM 722  C CB  . ALA A 1 94  ? 363.734 369.326 514.154 1.00 103.54 ? 94  ALA H CB  1 
ATOM 723  N N   . THR A 1 95  ? 362.003 371.606 514.600 1.00 99.68  ? 95  THR H N   1 
ATOM 724  C CA  . THR A 1 95  ? 360.869 372.439 514.221 1.00 99.68  ? 95  THR H CA  1 
ATOM 725  C C   . THR A 1 95  ? 360.576 372.197 512.748 1.00 99.68  ? 95  THR H C   1 
ATOM 726  O O   . THR A 1 95  ? 361.465 372.347 511.906 1.00 99.68  ? 95  THR H O   1 
ATOM 727  C CB  . THR A 1 95  ? 361.153 373.918 514.470 1.00 99.68  ? 95  THR H CB  1 
ATOM 728  O OG1 . THR A 1 95  ? 361.644 374.096 515.804 1.00 99.68  ? 95  THR H OG1 1 
ATOM 729  C CG2 . THR A 1 95  ? 359.892 374.736 514.286 1.00 99.68  ? 95  THR H CG2 1 
ATOM 730  N N   . TYR A 1 96  ? 359.341 371.824 512.440 1.00 97.43  ? 96  TYR H N   1 
ATOM 731  C CA  . TYR A 1 96  ? 358.971 371.381 511.105 1.00 97.43  ? 96  TYR H CA  1 
ATOM 732  C C   . TYR A 1 96  ? 358.207 372.475 510.381 1.00 97.43  ? 96  TYR H C   1 
ATOM 733  O O   . TYR A 1 96  ? 357.139 372.893 510.832 1.00 97.43  ? 96  TYR H O   1 
ATOM 734  C CB  . TYR A 1 96  ? 358.132 370.109 511.180 1.00 97.43  ? 96  TYR H CB  1 
ATOM 735  C CG  . TYR A 1 96  ? 358.953 368.880 511.464 1.00 97.43  ? 96  TYR H CG  1 
ATOM 736  C CD1 . TYR A 1 96  ? 359.308 368.546 512.758 1.00 97.43  ? 96  TYR H CD1 1 
ATOM 737  C CD2 . TYR A 1 96  ? 359.387 368.066 510.437 1.00 97.43  ? 96  TYR H CD2 1 
ATOM 738  C CE1 . TYR A 1 96  ? 360.066 367.434 513.018 1.00 97.43  ? 96  TYR H CE1 1 
ATOM 739  C CE2 . TYR A 1 96  ? 360.146 366.955 510.690 1.00 97.43  ? 96  TYR H CE2 1 
ATOM 740  C CZ  . TYR A 1 96  ? 360.481 366.644 511.981 1.00 97.43  ? 96  TYR H CZ  1 
ATOM 741  O OH  . TYR A 1 96  ? 361.237 365.529 512.232 1.00 97.43  ? 96  TYR H OH  1 
ATOM 742  N N   . TYR A 1 97  ? 358.747 372.921 509.255 1.00 94.71  ? 97  TYR H N   1 
ATOM 743  C CA  . TYR A 1 97  ? 358.173 373.996 508.465 1.00 94.71  ? 97  TYR H CA  1 
ATOM 744  C C   . TYR A 1 97  ? 357.409 373.428 507.279 1.00 94.71  ? 97  TYR H C   1 
ATOM 745  O O   . TYR A 1 97  ? 357.446 372.234 506.998 1.00 94.71  ? 97  TYR H O   1 
ATOM 746  C CB  . TYR A 1 97  ? 359.258 374.954 507.992 1.00 94.71  ? 97  TYR H CB  1 
ATOM 747  C CG  . TYR A 1 97  ? 359.880 375.740 509.103 1.00 94.71  ? 97  TYR H CG  1 
ATOM 748  C CD1 . TYR A 1 97  ? 359.162 376.718 509.766 1.00 94.71  ? 97  TYR H CD1 1 
ATOM 749  C CD2 . TYR A 1 97  ? 361.189 375.516 509.483 1.00 94.71  ? 97  TYR H CD2 1 
ATOM 750  C CE1 . TYR A 1 97  ? 359.733 377.447 510.789 1.00 94.71  ? 97  TYR H CE1 1 
ATOM 751  C CE2 . TYR A 1 97  ? 361.768 376.238 510.500 1.00 94.71  ? 97  TYR H CE2 1 
ATOM 752  C CZ  . TYR A 1 97  ? 361.036 377.200 511.148 1.00 94.71  ? 97  TYR H CZ  1 
ATOM 753  O OH  . TYR A 1 97  ? 361.615 377.919 512.161 1.00 94.71  ? 97  TYR H OH  1 
ATOM 754  N N   . CYS A 1 98  ? 356.721 374.318 506.571 1.00 95.21  ? 98  CYS H N   1 
ATOM 755  C CA  . CYS A 1 98  ? 355.861 373.948 505.451 1.00 95.21  ? 98  CYS H CA  1 
ATOM 756  C C   . CYS A 1 98  ? 356.039 375.053 504.416 1.00 95.21  ? 98  CYS H C   1 
ATOM 757  O O   . CYS A 1 98  ? 355.687 376.204 504.682 1.00 95.21  ? 98  CYS H O   1 
ATOM 758  C CB  . CYS A 1 98  ? 354.414 373.814 505.904 1.00 95.21  ? 98  CYS H CB  1 
ATOM 759  S SG  . CYS A 1 98  ? 353.201 373.356 504.645 1.00 95.21  ? 98  CYS H SG  1 
ATOM 760  N N   . ALA A 1 99  ? 356.611 374.713 503.268 1.00 83.51  ? 99  ALA H N   1 
ATOM 761  C CA  . ALA A 1 99  ? 356.994 375.710 502.280 1.00 83.51  ? 99  ALA H CA  1 
ATOM 762  C C   . ALA A 1 99  ? 356.320 375.461 500.937 1.00 83.51  ? 99  ALA H C   1 
ATOM 763  O O   . ALA A 1 99  ? 355.736 374.408 500.690 1.00 83.51  ? 99  ALA H O   1 
ATOM 764  C CB  . ALA A 1 99  ? 358.509 375.735 502.103 1.00 83.51  ? 99  ALA H CB  1 
ATOM 765  N N   . ARG A 1 100 ? 356.419 376.457 500.067 1.00 79.25  ? 100 ARG H N   1 
ATOM 766  C CA  . ARG A 1 100 ? 355.783 376.466 498.760 1.00 79.25  ? 100 ARG H CA  1 
ATOM 767  C C   . ARG A 1 100 ? 356.790 376.906 497.707 1.00 79.25  ? 100 ARG H C   1 
ATOM 768  O O   . ARG A 1 100 ? 357.738 377.631 498.000 1.00 79.25  ? 100 ARG H O   1 
ATOM 769  C CB  . ARG A 1 100 ? 354.581 377.410 498.772 1.00 79.25  ? 100 ARG H CB  1 
ATOM 770  C CG  . ARG A 1 100 ? 353.595 377.261 497.644 1.00 79.25  ? 100 ARG H CG  1 
ATOM 771  C CD  . ARG A 1 100 ? 352.583 378.357 497.770 1.00 79.25  ? 100 ARG H CD  1 
ATOM 772  N NE  . ARG A 1 100 ? 353.204 379.648 497.510 1.00 79.25  ? 100 ARG H NE  1 
ATOM 773  C CZ  . ARG A 1 100 ? 353.068 380.322 496.379 1.00 79.25  ? 100 ARG H CZ  1 
ATOM 774  N NH1 . ARG A 1 100 ? 352.294 379.848 495.420 1.00 79.25  ? 100 ARG H NH1 1 
ATOM 775  N NH2 . ARG A 1 100 ? 353.678 381.481 496.221 1.00 79.25  ? 100 ARG H NH2 1 
ATOM 776  N N   . SER A 1 101 ? 356.590 376.460 496.474 1.00 75.09  ? 101 SER H N   1 
ATOM 777  C CA  . SER A 1 101 ? 357.457 376.843 495.375 1.00 75.09  ? 101 SER H CA  1 
ATOM 778  C C   . SER A 1 101 ? 356.619 377.358 494.217 1.00 75.09  ? 101 SER H C   1 
ATOM 779  O O   . SER A 1 101 ? 355.429 377.065 494.106 1.00 75.09  ? 101 SER H O   1 
ATOM 780  C CB  . SER A 1 101 ? 358.310 375.669 494.907 1.00 75.09  ? 101 SER H CB  1 
ATOM 781  O OG  . SER A 1 101 ? 359.075 375.142 495.964 1.00 75.09  ? 101 SER H OG  1 
ATOM 782  N N   . ARG A 1 102 ? 357.254 378.119 493.332 0.00 72.57  ? 102 ARG H N   1 
ATOM 783  C CA  . ARG A 1 102 ? 356.560 378.612 492.157 0.00 72.57  ? 102 ARG H CA  1 
ATOM 784  C C   . ARG A 1 102 ? 357.516 378.667 490.979 0.00 72.57  ? 102 ARG H C   1 
ATOM 785  O O   . ARG A 1 102 ? 358.727 378.502 491.125 0.00 72.57  ? 102 ARG H O   1 
ATOM 786  C CB  . ARG A 1 102 ? 355.946 379.987 492.399 0.00 72.57  ? 102 ARG H CB  1 
ATOM 787  C CG  . ARG A 1 102 ? 356.938 381.067 492.719 0.00 72.57  ? 102 ARG H CG  1 
ATOM 788  C CD  . ARG A 1 102 ? 356.209 382.371 492.898 0.00 72.57  ? 102 ARG H CD  1 
ATOM 789  N NE  . ARG A 1 102 ? 355.764 382.892 491.616 0.00 72.57  ? 102 ARG H NE  1 
ATOM 790  C CZ  . ARG A 1 102 ? 356.329 383.913 490.988 0.00 72.57  ? 102 ARG H CZ  1 
ATOM 791  N NH1 . ARG A 1 102 ? 357.335 384.558 491.548 0.00 72.57  ? 102 ARG H NH1 1 
ATOM 792  N NH2 . ARG A 1 102 ? 355.862 384.314 489.817 0.00 72.57  ? 102 ARG H NH2 1 
ATOM 793  N N   . TYR A 1 103 ? 356.946 378.890 489.805 1.00 68.52  ? 103 TYR H N   1 
ATOM 794  C CA  . TYR A 1 103 ? 357.709 379.039 488.578 1.00 68.52  ? 103 TYR H CA  1 
ATOM 795  C C   . TYR A 1 103 ? 358.080 380.505 488.417 1.00 68.52  ? 103 TYR H C   1 
ATOM 796  O O   . TYR A 1 103 ? 357.232 381.382 488.604 1.00 68.52  ? 103 TYR H O   1 
ATOM 797  C CB  . TYR A 1 103 ? 356.895 378.565 487.380 1.00 68.52  ? 103 TYR H CB  1 
ATOM 798  C CG  . TYR A 1 103 ? 356.647 377.085 487.344 1.00 68.52  ? 103 TYR H CG  1 
ATOM 799  C CD1 . TYR A 1 103 ? 355.551 376.535 487.972 1.00 68.52  ? 103 TYR H CD1 1 
ATOM 800  C CD2 . TYR A 1 103 ? 357.504 376.240 486.667 1.00 68.52  ? 103 TYR H CD2 1 
ATOM 801  C CE1 . TYR A 1 103 ? 355.322 375.189 487.935 1.00 68.52  ? 103 TYR H CE1 1 
ATOM 802  C CE2 . TYR A 1 103 ? 357.280 374.892 486.625 1.00 68.52  ? 103 TYR H CE2 1 
ATOM 803  C CZ  . TYR A 1 103 ? 356.191 374.378 487.261 1.00 68.52  ? 103 TYR H CZ  1 
ATOM 804  O OH  . TYR A 1 103 ? 355.969 373.032 487.220 1.00 68.52  ? 103 TYR H OH  1 
ATOM 805  N N   . TYR A 1 104 ? 359.334 380.775 488.063 1.00 71.80  ? 104 TYR H N   1 
ATOM 806  C CA  . TYR A 1 104 ? 359.790 382.159 488.028 1.00 71.80  ? 104 TYR H CA  1 
ATOM 807  C C   . TYR A 1 104 ? 359.810 382.727 486.613 1.00 71.80  ? 104 TYR H C   1 
ATOM 808  O O   . TYR A 1 104 ? 359.300 383.825 486.373 1.00 71.80  ? 104 TYR H O   1 
ATOM 809  C CB  . TYR A 1 104 ? 361.150 382.261 488.706 1.00 71.80  ? 104 TYR H CB  1 
ATOM 810  C CG  . TYR A 1 104 ? 360.994 382.224 490.193 1.00 71.80  ? 104 TYR H CG  1 
ATOM 811  C CD1 . TYR A 1 104 ? 360.312 383.225 490.854 1.00 71.80  ? 104 TYR H CD1 1 
ATOM 812  C CD2 . TYR A 1 104 ? 361.485 381.168 490.932 1.00 71.80  ? 104 TYR H CD2 1 
ATOM 813  C CE1 . TYR A 1 104 ? 360.148 383.188 492.211 1.00 71.80  ? 104 TYR H CE1 1 
ATOM 814  C CE2 . TYR A 1 104 ? 361.325 381.124 492.295 1.00 71.80  ? 104 TYR H CE2 1 
ATOM 815  C CZ  . TYR A 1 104 ? 360.653 382.137 492.926 1.00 71.80  ? 104 TYR H CZ  1 
ATOM 816  O OH  . TYR A 1 104 ? 360.487 382.102 494.285 1.00 71.80  ? 104 TYR H OH  1 
ATOM 817  N N   . GLY A 1 105 ? 360.387 382.005 485.672 1.00 69.48  ? 105 GLY H N   1 
ATOM 818  C CA  . GLY A 1 105 ? 360.094 382.302 484.289 1.00 69.48  ? 105 GLY H CA  1 
ATOM 819  C C   . GLY A 1 105 ? 358.915 381.437 483.925 1.00 69.48  ? 105 GLY H C   1 
ATOM 820  O O   . GLY A 1 105 ? 357.824 381.593 484.475 1.00 69.48  ? 105 GLY H O   1 
ATOM 821  N N   . GLY A 1 106 ? 359.118 380.521 482.999 1.00 68.57  ? 106 GLY H N   1 
ATOM 822  C CA  . GLY A 1 106 ? 358.321 379.324 482.953 1.00 68.57  ? 106 GLY H CA  1 
ATOM 823  C C   . GLY A 1 106 ? 359.052 378.159 483.557 1.00 68.57  ? 106 GLY H C   1 
ATOM 824  O O   . GLY A 1 106 ? 358.533 377.042 483.553 1.00 68.57  ? 106 GLY H O   1 
ATOM 825  N N   . THR A 1 107 ? 360.252 378.392 484.073 1.00 68.02  ? 107 THR H N   1 
ATOM 826  C CA  . THR A 1 107 ? 361.109 377.360 484.617 1.00 68.02  ? 107 THR H CA  1 
ATOM 827  C C   . THR A 1 107 ? 360.828 377.159 486.095 1.00 68.02  ? 107 THR H C   1 
ATOM 828  O O   . THR A 1 107 ? 360.279 378.023 486.771 1.00 68.02  ? 107 THR H O   1 
ATOM 829  C CB  . THR A 1 107 ? 362.571 377.733 484.436 1.00 68.02  ? 107 THR H CB  1 
ATOM 830  O OG1 . THR A 1 107 ? 362.757 379.095 484.829 1.00 68.02  ? 107 THR H OG1 1 
ATOM 831  C CG2 . THR A 1 107 ? 362.969 377.594 483.001 1.00 68.02  ? 107 THR H CG2 1 
ATOM 832  N N   . TYR A 1 108 ? 361.234 376.010 486.601 0.00 71.35  ? 108 TYR H N   1 
ATOM 833  C CA  . TYR A 1 108 ? 361.103 375.696 488.013 0.00 71.35  ? 108 TYR H CA  1 
ATOM 834  C C   . TYR A 1 108 ? 362.485 375.797 488.632 0.00 71.35  ? 108 TYR H C   1 
ATOM 835  O O   . TYR A 1 108 ? 363.257 374.842 488.621 0.00 71.35  ? 108 TYR H O   1 
ATOM 836  C CB  . TYR A 1 108 ? 360.512 374.320 488.234 0.00 71.35  ? 108 TYR H CB  1 
ATOM 837  C CG  . TYR A 1 108 ? 360.343 373.978 489.690 0.00 71.35  ? 108 TYR H CG  1 
ATOM 838  C CD1 . TYR A 1 108 ? 359.335 374.542 490.436 0.00 71.35  ? 108 TYR H CD1 1 
ATOM 839  C CD2 . TYR A 1 108 ? 361.192 373.093 490.313 0.00 71.35  ? 108 TYR H CD2 1 
ATOM 840  C CE1 . TYR A 1 108 ? 359.181 374.235 491.752 0.00 71.35  ? 108 TYR H CE1 1 
ATOM 841  C CE2 . TYR A 1 108 ? 361.043 372.784 491.633 0.00 71.35  ? 108 TYR H CE2 1 
ATOM 842  C CZ  . TYR A 1 108 ? 360.039 373.357 492.343 0.00 71.35  ? 108 TYR H CZ  1 
ATOM 843  O OH  . TYR A 1 108 ? 359.893 373.046 493.663 0.00 71.35  ? 108 TYR H OH  1 
ATOM 844  N N   . ARG A 1 109 ? 362.803 376.968 489.156 0.00 72.42  ? 109 ARG H N   1 
ATOM 845  C CA  . ARG A 1 109 ? 363.919 377.055 490.070 0.00 72.42  ? 109 ARG H CA  1 
ATOM 846  C C   . ARG A 1 109 ? 363.471 376.501 491.413 0.00 72.42  ? 109 ARG H C   1 
ATOM 847  O O   . ARG A 1 109 ? 362.295 376.563 491.770 0.00 72.42  ? 109 ARG H O   1 
ATOM 848  C CB  . ARG A 1 109 ? 364.402 378.495 490.200 0.00 72.42  ? 109 ARG H CB  1 
ATOM 849  C CG  . ARG A 1 109 ? 364.985 379.076 488.922 0.00 72.42  ? 109 ARG H CG  1 
ATOM 850  C CD  . ARG A 1 109 ? 363.956 379.886 488.182 0.00 72.42  ? 109 ARG H CD  1 
ATOM 851  N NE  . ARG A 1 109 ? 364.465 380.526 486.983 0.00 72.42  ? 109 ARG H NE  1 
ATOM 852  C CZ  . ARG A 1 109 ? 364.996 381.736 486.970 0.00 72.42  ? 109 ARG H CZ  1 
ATOM 853  N NH1 . ARG A 1 109 ? 365.427 382.262 485.840 0.00 72.42  ? 109 ARG H NH1 1 
ATOM 854  N NH2 . ARG A 1 109 ? 365.103 382.418 488.095 0.00 72.42  ? 109 ARG H NH2 1 
ATOM 855  N N   . TYR A 1 110 ? 364.414 375.954 492.169 0.00 73.50  ? 110 TYR H N   1 
ATOM 856  C CA  . TYR A 1 110 ? 364.062 375.122 493.316 0.00 73.50  ? 110 TYR H CA  1 
ATOM 857  C C   . TYR A 1 110 ? 363.935 375.925 494.599 0.00 73.50  ? 110 TYR H C   1 
ATOM 858  O O   . TYR A 1 110 ? 364.200 375.413 495.685 0.00 73.50  ? 110 TYR H O   1 
ATOM 859  C CB  . TYR A 1 110 ? 365.076 374.003 493.478 0.00 73.50  ? 110 TYR H CB  1 
ATOM 860  C CG  . TYR A 1 110 ? 364.882 372.900 492.479 0.00 73.50  ? 110 TYR H CG  1 
ATOM 861  C CD1 . TYR A 1 110 ? 365.373 373.014 491.196 0.00 73.50  ? 110 TYR H CD1 1 
ATOM 862  C CD2 . TYR A 1 110 ? 364.192 371.751 492.811 0.00 73.50  ? 110 TYR H CD2 1 
ATOM 863  C CE1 . TYR A 1 110 ? 365.191 372.019 490.276 0.00 73.50  ? 110 TYR H CE1 1 
ATOM 864  C CE2 . TYR A 1 110 ? 364.009 370.746 491.893 0.00 73.50  ? 110 TYR H CE2 1 
ATOM 865  C CZ  . TYR A 1 110 ? 364.516 370.889 490.628 0.00 73.50  ? 110 TYR H CZ  1 
ATOM 866  O OH  . TYR A 1 110 ? 364.343 369.901 489.696 0.00 73.50  ? 110 TYR H OH  1 
ATOM 867  N N   . ALA A 1 111 ? 363.519 377.180 494.502 0.67 74.66  ? 111 ALA H N   1 
ATOM 868  C CA  . ALA A 1 111 ? 363.439 378.054 495.655 0.67 74.66  ? 111 ALA H CA  1 
ATOM 869  C C   . ALA A 1 111 ? 362.147 377.820 496.413 0.67 74.66  ? 111 ALA H C   1 
ATOM 870  O O   . ALA A 1 111 ? 361.211 377.197 495.916 0.67 74.66  ? 111 ALA H O   1 
ATOM 871  C CB  . ALA A 1 111 ? 363.523 379.512 495.228 0.67 74.66  ? 111 ALA H CB  1 
ATOM 872  N N   . LEU A 1 112 ? 362.103 378.337 497.638 1.00 79.59  ? 112 LEU H N   1 
ATOM 873  C CA  . LEU A 1 112 ? 360.948 378.200 498.522 1.00 79.59  ? 112 LEU H CA  1 
ATOM 874  C C   . LEU A 1 112 ? 360.513 379.612 498.900 1.00 79.59  ? 112 LEU H C   1 
ATOM 875  O O   . LEU A 1 112 ? 361.215 380.295 499.647 1.00 79.59  ? 112 LEU H O   1 
ATOM 876  C CB  . LEU A 1 112 ? 361.311 377.386 499.753 1.00 79.59  ? 112 LEU H CB  1 
ATOM 877  C CG  . LEU A 1 112 ? 361.954 376.039 499.447 1.00 79.59  ? 112 LEU H CG  1 
ATOM 878  C CD1 . LEU A 1 112 ? 362.372 375.319 500.694 1.00 79.59  ? 112 LEU H CD1 1 
ATOM 879  C CD2 . LEU A 1 112 ? 361.024 375.204 498.656 1.00 79.59  ? 112 LEU H CD2 1 
ATOM 880  N N   . ASP A 1 113 ? 359.361 380.061 498.406 1.00 84.49  ? 113 ASP H N   1 
ATOM 881  C CA  . ASP A 1 113 ? 359.043 381.480 498.535 1.00 84.49  ? 113 ASP H CA  1 
ATOM 882  C C   . ASP A 1 113 ? 358.317 381.817 499.841 1.00 84.49  ? 113 ASP H C   1 
ATOM 883  O O   . ASP A 1 113 ? 358.646 382.812 500.491 1.00 84.49  ? 113 ASP H O   1 
ATOM 884  C CB  . ASP A 1 113 ? 358.256 381.969 497.307 1.00 84.49  ? 113 ASP H CB  1 
ATOM 885  C CG  . ASP A 1 113 ? 356.905 381.297 497.145 1.00 84.49  ? 113 ASP H CG  1 
ATOM 886  O OD1 . ASP A 1 113 ? 356.654 380.268 497.796 1.00 84.49  ? 113 ASP H OD1 1 
ATOM 887  O OD2 . ASP A 1 113 ? 356.075 381.812 496.369 1.00 84.49  ? 113 ASP H OD2 1 
ATOM 888  N N   . TYR A 1 114 ? 357.329 381.019 500.234 1.00 86.22  ? 114 TYR H N   1 
ATOM 889  C CA  . TYR A 1 114 ? 356.538 381.300 501.425 1.00 86.22  ? 114 TYR H CA  1 
ATOM 890  C C   . TYR A 1 114 ? 356.671 380.152 502.409 1.00 86.22  ? 114 TYR H C   1 
ATOM 891  O O   . TYR A 1 114 ? 356.614 378.987 502.014 1.00 86.22  ? 114 TYR H O   1 
ATOM 892  C CB  . TYR A 1 114 ? 355.074 381.524 501.071 1.00 86.22  ? 114 TYR H CB  1 
ATOM 893  C CG  . TYR A 1 114 ? 354.824 382.841 500.399 1.00 86.22  ? 114 TYR H CG  1 
ATOM 894  C CD1 . TYR A 1 114 ? 354.962 384.026 501.094 1.00 86.22  ? 114 TYR H CD1 1 
ATOM 895  C CD2 . TYR A 1 114 ? 354.448 382.899 499.070 1.00 86.22  ? 114 TYR H CD2 1 
ATOM 896  C CE1 . TYR A 1 114 ? 354.735 385.232 500.485 1.00 86.22  ? 114 TYR H CE1 1 
ATOM 897  C CE2 . TYR A 1 114 ? 354.221 384.098 498.451 1.00 86.22  ? 114 TYR H CE2 1 
ATOM 898  C CZ  . TYR A 1 114 ? 354.363 385.263 499.163 1.00 86.22  ? 114 TYR H CZ  1 
ATOM 899  O OH  . TYR A 1 114 ? 354.136 386.472 498.552 1.00 86.22  ? 114 TYR H OH  1 
ATOM 900  N N   . TRP A 1 115 ? 356.828 380.481 503.684 1.00 87.97  ? 115 TRP H N   1 
ATOM 901  C CA  . TRP A 1 115 ? 357.108 379.501 504.717 1.00 87.97  ? 115 TRP H CA  1 
ATOM 902  C C   . TRP A 1 115 ? 356.036 379.542 505.796 1.00 87.97  ? 115 TRP H C   1 
ATOM 903  O O   . TRP A 1 115 ? 355.460 380.593 506.083 1.00 87.97  ? 115 TRP H O   1 
ATOM 904  C CB  . TRP A 1 115 ? 358.474 379.753 505.355 1.00 87.97  ? 115 TRP H CB  1 
ATOM 905  C CG  . TRP A 1 115 ? 359.642 379.479 504.470 1.00 87.97  ? 115 TRP H CG  1 
ATOM 906  C CD1 . TRP A 1 115 ? 359.928 380.072 503.283 1.00 87.97  ? 115 TRP H CD1 1 
ATOM 907  C CD2 . TRP A 1 115 ? 360.696 378.552 504.716 1.00 87.97  ? 115 TRP H CD2 1 
ATOM 908  N NE1 . TRP A 1 115 ? 361.089 379.565 502.768 1.00 87.97  ? 115 TRP H NE1 1 
ATOM 909  C CE2 . TRP A 1 115 ? 361.580 378.627 503.633 1.00 87.97  ? 115 TRP H CE2 1 
ATOM 910  C CE3 . TRP A 1 115 ? 360.975 377.663 505.748 1.00 87.97  ? 115 TRP H CE3 1 
ATOM 911  C CZ2 . TRP A 1 115 ? 362.719 377.850 503.552 1.00 87.97  ? 115 TRP H CZ2 1 
ATOM 912  C CZ3 . TRP A 1 115 ? 362.103 376.892 505.664 1.00 87.97  ? 115 TRP H CZ3 1 
ATOM 913  C CH2 . TRP A 1 115 ? 362.962 376.988 504.577 1.00 87.97  ? 115 TRP H CH2 1 
ATOM 914  N N   . GLY A 1 116 ? 355.781 378.388 506.398 1.00 96.83  ? 116 GLY H N   1 
ATOM 915  C CA  . GLY A 1 116 ? 354.862 378.316 507.511 1.00 96.83  ? 116 GLY H CA  1 
ATOM 916  C C   . GLY A 1 116 ? 355.500 378.755 508.811 1.00 96.83  ? 116 GLY H C   1 
ATOM 917  O O   . GLY A 1 116 ? 356.710 378.937 508.914 1.00 96.83  ? 116 GLY H O   1 
ATOM 918  N N   . GLN A 1 117 ? 354.662 378.920 509.831 1.00 100.77 ? 117 GLN H N   1 
ATOM 919  C CA  . GLN A 1 117 ? 355.132 379.475 511.092 1.00 100.77 ? 117 GLN H CA  1 
ATOM 920  C C   . GLN A 1 117 ? 355.926 378.486 511.934 1.00 100.77 ? 117 GLN H C   1 
ATOM 921  O O   . GLN A 1 117 ? 356.694 378.919 512.798 1.00 100.77 ? 117 GLN H O   1 
ATOM 922  C CB  . GLN A 1 117 ? 353.946 380.025 511.885 1.00 100.77 ? 117 GLN H CB  1 
ATOM 923  C CG  . GLN A 1 117 ? 352.669 379.217 511.753 1.00 100.77 ? 117 GLN H CG  1 
ATOM 924  C CD  . GLN A 1 117 ? 352.647 377.981 512.623 1.00 100.77 ? 117 GLN H CD  1 
ATOM 925  O OE1 . GLN A 1 117 ? 353.372 377.889 513.611 1.00 100.77 ? 117 GLN H OE1 1 
ATOM 926  N NE2 . GLN A 1 117 ? 351.802 377.022 512.264 1.00 100.77 ? 117 GLN H NE2 1 
ATOM 927  N N   . GLY A 1 118 ? 355.779 377.186 511.704 1.00 100.88 ? 118 GLY H N   1 
ATOM 928  C CA  . GLY A 1 118 ? 356.599 376.215 512.402 1.00 100.88 ? 118 GLY H CA  1 
ATOM 929  C C   . GLY A 1 118 ? 355.961 375.580 513.618 1.00 100.88 ? 118 GLY H C   1 
ATOM 930  O O   . GLY A 1 118 ? 355.677 376.263 514.605 1.00 100.88 ? 118 GLY H O   1 
ATOM 931  N N   . THR A 1 119 ? 355.730 374.273 513.562 1.00 102.24 ? 119 THR H N   1 
ATOM 932  C CA  . THR A 1 119 ? 355.358 373.499 514.734 1.00 102.24 ? 119 THR H CA  1 
ATOM 933  C C   . THR A 1 119 ? 356.564 372.724 515.236 1.00 102.24 ? 119 THR H C   1 
ATOM 934  O O   . THR A 1 119 ? 357.493 372.419 514.486 1.00 102.24 ? 119 THR H O   1 
ATOM 935  C CB  . THR A 1 119 ? 354.216 372.529 514.435 1.00 102.24 ? 119 THR H CB  1 
ATOM 936  O OG1 . THR A 1 119 ? 354.555 371.724 513.303 1.00 102.24 ? 119 THR H OG1 1 
ATOM 937  C CG2 . THR A 1 119 ? 352.953 373.285 514.153 1.00 102.24 ? 119 THR H CG2 1 
ATOM 938  N N   . SER A 1 120 ? 356.536 372.392 516.518 1.00 103.62 ? 120 SER H N   1 
ATOM 939  C CA  . SER A 1 120 ? 357.676 371.785 517.179 1.00 103.62 ? 120 SER H CA  1 
ATOM 940  C C   . SER A 1 120 ? 357.349 370.350 517.559 1.00 103.62 ? 120 SER H C   1 
ATOM 941  O O   . SER A 1 120 ? 356.255 370.058 518.049 1.00 103.62 ? 120 SER H O   1 
ATOM 942  C CB  . SER A 1 120 ? 358.080 372.583 518.414 1.00 103.62 ? 120 SER H CB  1 
ATOM 943  O OG  . SER A 1 120 ? 359.196 371.994 519.047 1.00 103.62 ? 120 SER H OG  1 
ATOM 944  N N   . VAL A 1 121 ? 358.306 369.458 517.319 1.00 105.88 ? 121 VAL H N   1 
ATOM 945  C CA  . VAL A 1 121 ? 358.164 368.037 517.601 1.00 105.88 ? 121 VAL H CA  1 
ATOM 946  C C   . VAL A 1 121 ? 359.364 367.632 518.436 1.00 105.88 ? 121 VAL H C   1 
ATOM 947  O O   . VAL A 1 121 ? 360.500 367.956 518.079 1.00 105.88 ? 121 VAL H O   1 
ATOM 948  C CB  . VAL A 1 121 ? 358.092 367.197 516.314 1.00 105.88 ? 121 VAL H CB  1 
ATOM 949  C CG1 . VAL A 1 121 ? 358.275 365.723 516.606 1.00 105.88 ? 121 VAL H CG1 1 
ATOM 950  C CG2 . VAL A 1 121 ? 356.777 367.423 515.612 1.00 105.88 ? 121 VAL H CG2 1 
ATOM 951  N N   . THR A 1 122 ? 359.120 366.960 519.557 1.00 113.02 ? 122 THR H N   1 
ATOM 952  C CA  . THR A 1 122 ? 360.185 366.453 520.404 1.00 113.02 ? 122 THR H CA  1 
ATOM 953  C C   . THR A 1 122 ? 359.833 365.066 520.925 1.00 113.02 ? 122 THR H C   1 
ATOM 954  O O   . THR A 1 122 ? 358.659 364.717 521.071 1.00 113.02 ? 122 THR H O   1 
ATOM 955  C CB  . THR A 1 122 ? 360.455 367.400 521.564 1.00 113.02 ? 122 THR H CB  1 
ATOM 956  O OG1 . THR A 1 122 ? 361.363 366.782 522.481 1.00 113.02 ? 122 THR H OG1 1 
ATOM 957  C CG2 . THR A 1 122 ? 359.165 367.757 522.274 1.00 113.02 ? 122 THR H CG2 1 
ATOM 958  N N   . VAL A 1 123 ? 360.867 364.274 521.202 1.00 116.53 ? 123 VAL H N   1 
ATOM 959  C CA  . VAL A 1 123 ? 360.706 362.891 521.628 1.00 116.53 ? 123 VAL H CA  1 
ATOM 960  C C   . VAL A 1 123 ? 361.198 362.744 523.062 1.00 116.53 ? 123 VAL H C   1 
ATOM 961  O O   . VAL A 1 123 ? 361.888 363.612 523.600 1.00 116.53 ? 123 VAL H O   1 
ATOM 962  C CB  . VAL A 1 123 ? 361.454 361.915 520.701 1.00 116.53 ? 123 VAL H CB  1 
ATOM 963  C CG1 . VAL A 1 123 ? 361.026 362.126 519.268 1.00 116.53 ? 123 VAL H CG1 1 
ATOM 964  C CG2 . VAL A 1 123 ? 362.950 362.099 520.836 1.00 116.53 ? 123 VAL H CG2 1 
ATOM 965  N N   . SER A 1 124 ? 360.833 361.627 523.684 1.00 119.05 ? 124 SER H N   1 
ATOM 966  C CA  . SER A 1 124 ? 361.210 361.393 525.076 1.00 119.05 ? 124 SER H CA  1 
ATOM 967  C C   . SER A 1 124 ? 361.660 359.964 525.328 1.00 119.05 ? 124 SER H C   1 
ATOM 968  O O   . SER A 1 124 ? 360.982 359.209 526.023 1.00 119.05 ? 124 SER H O   1 
ATOM 969  C CB  . SER A 1 124 ? 360.048 361.728 526.009 1.00 119.05 ? 124 SER H CB  1 
ATOM 970  O OG  . SER A 1 124 ? 360.191 361.076 527.262 1.00 119.05 ? 124 SER H OG  1 
ATOM 971  N N   . ASN B 2 2   ? 377.058 367.079 497.961 1.00 88.82  ? 2   ASN L N   1 
ATOM 972  C CA  . ASN B 2 2   ? 377.411 368.453 497.638 1.00 88.82  ? 2   ASN L CA  1 
ATOM 973  C C   . ASN B 2 2   ? 377.101 369.374 498.799 1.00 88.82  ? 2   ASN L C   1 
ATOM 974  O O   . ASN B 2 2   ? 375.960 369.763 498.996 1.00 88.82  ? 2   ASN L O   1 
ATOM 975  C CB  . ASN B 2 2   ? 376.666 368.917 496.395 1.00 88.82  ? 2   ASN L CB  1 
ATOM 976  C CG  . ASN B 2 2   ? 377.323 370.104 495.737 1.00 88.82  ? 2   ASN L CG  1 
ATOM 977  O OD1 . ASN B 2 2   ? 378.426 370.495 496.107 1.00 88.82  ? 2   ASN L OD1 1 
ATOM 978  N ND2 . ASN B 2 2   ? 376.655 370.680 494.749 1.00 88.82  ? 2   ASN L ND2 1 
ATOM 979  N N   . VAL B 2 3   ? 378.125 369.737 499.560 1.00 91.51  ? 3   VAL L N   1 
ATOM 980  C CA  . VAL B 2 3   ? 377.947 370.503 500.783 1.00 91.51  ? 3   VAL L CA  1 
ATOM 981  C C   . VAL B 2 3   ? 378.463 371.919 500.581 1.00 91.51  ? 3   VAL L C   1 
ATOM 982  O O   . VAL B 2 3   ? 379.375 372.167 499.787 1.00 91.51  ? 3   VAL L O   1 
ATOM 983  C CB  . VAL B 2 3   ? 378.642 369.828 501.984 1.00 91.51  ? 3   VAL L CB  1 
ATOM 984  C CG1 . VAL B 2 3   ? 377.970 368.512 502.294 1.00 91.51  ? 3   VAL L CG1 1 
ATOM 985  C CG2 . VAL B 2 3   ? 380.097 369.588 501.679 1.00 91.51  ? 3   VAL L CG2 1 
ATOM 986  N N   . LEU B 2 4   ? 377.854 372.852 501.301 1.00 93.09  ? 4   LEU L N   1 
ATOM 987  C CA  . LEU B 2 4   ? 378.166 374.269 501.208 1.00 93.09  ? 4   LEU L CA  1 
ATOM 988  C C   . LEU B 2 4   ? 378.799 374.724 502.512 1.00 93.09  ? 4   LEU L C   1 
ATOM 989  O O   . LEU B 2 4   ? 378.321 374.370 503.593 1.00 93.09  ? 4   LEU L O   1 
ATOM 990  C CB  . LEU B 2 4   ? 376.905 375.085 500.942 1.00 93.09  ? 4   LEU L CB  1 
ATOM 991  C CG  . LEU B 2 4   ? 376.154 374.866 499.640 1.00 93.09  ? 4   LEU L CG  1 
ATOM 992  C CD1 . LEU B 2 4   ? 374.840 375.574 499.723 1.00 93.09  ? 4   LEU L CD1 1 
ATOM 993  C CD2 . LEU B 2 4   ? 376.944 375.432 498.522 1.00 93.09  ? 4   LEU L CD2 1 
ATOM 994  N N   . THR B 2 5   ? 379.867 375.506 502.410 1.00 99.70  ? 5   THR L N   1 
ATOM 995  C CA  . THR B 2 5   ? 380.536 376.077 503.570 1.00 99.70  ? 5   THR L CA  1 
ATOM 996  C C   . THR B 2 5   ? 380.389 377.585 503.504 1.00 99.70  ? 5   THR L C   1 
ATOM 997  O O   . THR B 2 5   ? 380.744 378.201 502.496 1.00 99.70  ? 5   THR L O   1 
ATOM 998  C CB  . THR B 2 5   ? 382.016 375.702 503.614 1.00 99.70  ? 5   THR L CB  1 
ATOM 999  O OG1 . THR B 2 5   ? 382.741 376.559 502.730 1.00 99.70  ? 5   THR L OG1 1 
ATOM 1000 C CG2 . THR B 2 5   ? 382.226 374.256 503.199 1.00 99.70  ? 5   THR L CG2 1 
ATOM 1001 N N   . GLN B 2 6   ? 379.865 378.174 504.566 1.00 103.04 ? 6   GLN L N   1 
ATOM 1002 C CA  . GLN B 2 6   ? 379.774 379.620 504.635 1.00 103.04 ? 6   GLN L CA  1 
ATOM 1003 C C   . GLN B 2 6   ? 380.853 380.189 505.542 1.00 103.04 ? 6   GLN L C   1 
ATOM 1004 O O   . GLN B 2 6   ? 381.145 379.659 506.614 1.00 103.04 ? 6   GLN L O   1 
ATOM 1005 C CB  . GLN B 2 6   ? 378.403 380.042 505.130 1.00 103.04 ? 6   GLN L CB  1 
ATOM 1006 C CG  . GLN B 2 6   ? 377.321 379.761 504.138 1.00 103.04 ? 6   GLN L CG  1 
ATOM 1007 C CD  . GLN B 2 6   ? 376.019 380.388 504.533 1.00 103.04 ? 6   GLN L CD  1 
ATOM 1008 O OE1 . GLN B 2 6   ? 375.892 380.957 505.611 1.00 103.04 ? 6   GLN L OE1 1 
ATOM 1009 N NE2 . GLN B 2 6   ? 375.047 380.307 503.655 1.00 103.04 ? 6   GLN L NE2 1 
ATOM 1010 N N   . SER B 2 7   ? 381.442 381.297 505.098 1.00 108.49 ? 7   SER L N   1 
ATOM 1011 C CA  . SER B 2 7   ? 382.480 381.935 505.853 1.00 108.49 ? 7   SER L CA  1 
ATOM 1012 C C   . SER B 2 7   ? 382.321 383.436 505.670 1.00 108.49 ? 7   SER L C   1 
ATOM 1013 O O   . SER B 2 7   ? 382.138 383.890 504.531 1.00 108.49 ? 7   SER L O   1 
ATOM 1014 C CB  . SER B 2 7   ? 383.875 381.496 505.413 1.00 108.49 ? 7   SER L CB  1 
ATOM 1015 O OG  . SER B 2 7   ? 384.164 381.943 504.103 1.00 108.49 ? 7   SER L OG  1 
ATOM 1016 N N   . PRO B 2 8   ? 382.390 384.229 506.745 1.00 112.04 ? 8   PRO L N   1 
ATOM 1017 C CA  . PRO B 2 8   ? 382.660 383.820 508.127 1.00 112.04 ? 8   PRO L CA  1 
ATOM 1018 C C   . PRO B 2 8   ? 381.410 383.362 508.876 1.00 112.04 ? 8   PRO L C   1 
ATOM 1019 O O   . PRO B 2 8   ? 380.309 383.749 508.499 1.00 112.04 ? 8   PRO L O   1 
ATOM 1020 C CB  . PRO B 2 8   ? 383.228 385.092 508.744 1.00 112.04 ? 8   PRO L CB  1 
ATOM 1021 C CG  . PRO B 2 8   ? 382.526 386.185 508.016 1.00 112.04 ? 8   PRO L CG  1 
ATOM 1022 C CD  . PRO B 2 8   ? 382.262 385.690 506.622 1.00 112.04 ? 8   PRO L CD  1 
ATOM 1023 N N   . PRO B 2 9   ? 381.580 382.529 509.906 1.00 111.75 ? 9   PRO L N   1 
ATOM 1024 C CA  . PRO B 2 9   ? 380.411 382.112 510.693 1.00 111.75 ? 9   PRO L CA  1 
ATOM 1025 C C   . PRO B 2 9   ? 379.804 383.239 511.503 1.00 111.75 ? 9   PRO L C   1 
ATOM 1026 O O   . PRO B 2 9   ? 378.580 383.405 511.510 1.00 111.75 ? 9   PRO L O   1 
ATOM 1027 C CB  . PRO B 2 9   ? 380.976 381.009 511.596 1.00 111.75 ? 9   PRO L CB  1 
ATOM 1028 C CG  . PRO B 2 9   ? 382.212 380.559 510.919 1.00 111.75 ? 9   PRO L CG  1 
ATOM 1029 C CD  . PRO B 2 9   ? 382.782 381.775 510.281 1.00 111.75 ? 9   PRO L CD  1 
ATOM 1030 N N   . ILE B 2 10  ? 380.626 384.018 512.192 1.00 115.63 ? 10  ILE L N   1 
ATOM 1031 C CA  . ILE B 2 10  ? 380.171 385.155 512.975 1.00 115.63 ? 10  ILE L CA  1 
ATOM 1032 C C   . ILE B 2 10  ? 380.764 386.406 512.352 1.00 115.63 ? 10  ILE L C   1 
ATOM 1033 O O   . ILE B 2 10  ? 381.975 386.474 512.117 1.00 115.63 ? 10  ILE L O   1 
ATOM 1034 C CB  . ILE B 2 10  ? 380.575 385.022 514.454 1.00 115.63 ? 10  ILE L CB  1 
ATOM 1035 C CG1 . ILE B 2 10  ? 379.903 383.793 515.073 1.00 115.63 ? 10  ILE L CG1 1 
ATOM 1036 C CG2 . ILE B 2 10  ? 380.243 386.290 515.232 1.00 115.63 ? 10  ILE L CG2 1 
ATOM 1037 C CD1 . ILE B 2 10  ? 378.417 383.966 515.339 1.00 115.63 ? 10  ILE L CD1 1 
ATOM 1038 N N   . MET B 2 11  ? 379.912 387.386 512.078 1.00 119.35 ? 11  MET L N   1 
ATOM 1039 C CA  . MET B 2 11  ? 380.329 388.607 511.411 1.00 119.35 ? 11  MET L CA  1 
ATOM 1040 C C   . MET B 2 11  ? 379.776 389.793 512.181 1.00 119.35 ? 11  MET L C   1 
ATOM 1041 O O   . MET B 2 11  ? 378.587 389.820 512.510 1.00 119.35 ? 11  MET L O   1 
ATOM 1042 C CB  . MET B 2 11  ? 379.838 388.614 509.966 1.00 119.35 ? 11  MET L CB  1 
ATOM 1043 C CG  . MET B 2 11  ? 379.607 389.970 509.365 1.00 119.35 ? 11  MET L CG  1 
ATOM 1044 S SD  . MET B 2 11  ? 378.621 389.766 507.882 1.00 119.35 ? 11  MET L SD  1 
ATOM 1045 C CE  . MET B 2 11  ? 379.799 388.900 506.850 1.00 119.35 ? 11  MET L CE  1 
ATOM 1046 N N   . SER B 2 12  ? 380.643 390.750 512.490 1.00 126.22 ? 12  SER L N   1 
ATOM 1047 C CA  . SER B 2 12  ? 380.254 391.955 513.200 1.00 126.22 ? 12  SER L CA  1 
ATOM 1048 C C   . SER B 2 12  ? 380.687 393.177 512.407 1.00 126.22 ? 12  SER L C   1 
ATOM 1049 O O   . SER B 2 12  ? 381.809 393.239 511.897 1.00 126.22 ? 12  SER L O   1 
ATOM 1050 C CB  . SER B 2 12  ? 380.861 392.002 514.605 1.00 126.22 ? 12  SER L CB  1 
ATOM 1051 O OG  . SER B 2 12  ? 382.226 391.624 514.586 1.00 126.22 ? 12  SER L OG  1 
ATOM 1052 N N   . ALA B 2 13  ? 379.787 394.150 512.313 1.00 123.51 ? 13  ALA L N   1 
ATOM 1053 C CA  . ALA B 2 13  ? 380.064 395.371 511.578 1.00 123.51 ? 13  ALA L CA  1 
ATOM 1054 C C   . ALA B 2 13  ? 379.136 396.473 512.062 1.00 123.51 ? 13  ALA L C   1 
ATOM 1055 O O   . ALA B 2 13  ? 377.968 396.225 512.370 1.00 123.51 ? 13  ALA L O   1 
ATOM 1056 C CB  . ALA B 2 13  ? 379.891 395.169 510.071 1.00 123.51 ? 13  ALA L CB  1 
ATOM 1057 N N   . SER B 2 14  ? 379.670 397.684 512.119 1.00 123.84 ? 14  SER L N   1 
ATOM 1058 C CA  . SER B 2 14  ? 378.909 398.868 512.465 1.00 123.84 ? 14  SER L CA  1 
ATOM 1059 C C   . SER B 2 14  ? 377.954 399.226 511.331 1.00 123.84 ? 14  SER L C   1 
ATOM 1060 O O   . SER B 2 14  ? 378.196 398.870 510.176 1.00 123.84 ? 14  SER L O   1 
ATOM 1061 C CB  . SER B 2 14  ? 379.864 400.021 512.746 1.00 123.84 ? 14  SER L CB  1 
ATOM 1062 O OG  . SER B 2 14  ? 380.600 400.356 511.585 1.00 123.84 ? 14  SER L OG  1 
ATOM 1063 N N   . PRO B 2 15  ? 376.842 399.899 511.637 1.00 123.69 ? 15  PRO L N   1 
ATOM 1064 C CA  . PRO B 2 15  ? 375.928 400.324 510.569 1.00 123.69 ? 15  PRO L CA  1 
ATOM 1065 C C   . PRO B 2 15  ? 376.560 401.402 509.705 1.00 123.69 ? 15  PRO L C   1 
ATOM 1066 O O   . PRO B 2 15  ? 377.334 402.229 510.189 1.00 123.69 ? 15  PRO L O   1 
ATOM 1067 C CB  . PRO B 2 15  ? 374.710 400.856 511.332 1.00 123.69 ? 15  PRO L CB  1 
ATOM 1068 C CG  . PRO B 2 15  ? 374.785 400.210 512.667 1.00 123.69 ? 15  PRO L CG  1 
ATOM 1069 C CD  . PRO B 2 15  ? 376.244 400.100 512.969 1.00 123.69 ? 15  PRO L CD  1 
ATOM 1070 N N   . GLY B 2 16  ? 376.239 401.370 508.417 1.00 121.62 ? 16  GLY L N   1 
ATOM 1071 C CA  . GLY B 2 16  ? 376.718 402.355 507.471 1.00 121.62 ? 16  GLY L CA  1 
ATOM 1072 C C   . GLY B 2 16  ? 377.837 401.878 506.577 1.00 121.62 ? 16  GLY L C   1 
ATOM 1073 O O   . GLY B 2 16  ? 378.133 402.547 505.579 1.00 121.62 ? 16  GLY L O   1 
ATOM 1074 N N   . GLU B 2 17  ? 378.470 400.753 506.895 1.00 122.36 ? 17  GLU L N   1 
ATOM 1075 C CA  . GLU B 2 17  ? 379.576 400.242 506.104 1.00 122.36 ? 17  GLU L CA  1 
ATOM 1076 C C   . GLU B 2 17  ? 379.117 399.092 505.213 1.00 122.36 ? 17  GLU L C   1 
ATOM 1077 O O   . GLU B 2 17  ? 377.972 398.646 505.267 1.00 122.36 ? 17  GLU L O   1 
ATOM 1078 C CB  . GLU B 2 17  ? 380.718 399.798 507.016 1.00 122.36 ? 17  GLU L CB  1 
ATOM 1079 C CG  . GLU B 2 17  ? 380.453 398.505 507.764 1.00 122.36 ? 17  GLU L CG  1 
ATOM 1080 C CD  . GLU B 2 17  ? 381.449 398.263 508.883 1.00 122.36 ? 17  GLU L CD  1 
ATOM 1081 O OE1 . GLU B 2 17  ? 381.502 399.085 509.822 1.00 122.36 ? 17  GLU L OE1 1 
ATOM 1082 O OE2 . GLU B 2 17  ? 382.185 397.256 508.818 1.00 122.36 ? 17  GLU L OE2 1 
ATOM 1083 N N   . LYS B 2 18  ? 380.035 398.617 504.377 1.00 115.08 ? 18  LYS L N   1 
ATOM 1084 C CA  . LYS B 2 18  ? 379.777 397.531 503.442 1.00 115.08 ? 18  LYS L CA  1 
ATOM 1085 C C   . LYS B 2 18  ? 380.408 396.250 503.967 1.00 115.08 ? 18  LYS L C   1 
ATOM 1086 O O   . LYS B 2 18  ? 381.592 396.238 504.315 1.00 115.08 ? 18  LYS L O   1 
ATOM 1087 C CB  . LYS B 2 18  ? 380.330 397.868 502.054 1.00 115.08 ? 18  LYS L CB  1 
ATOM 1088 C CG  . LYS B 2 18  ? 380.163 396.772 501.011 1.00 115.08 ? 18  LYS L CG  1 
ATOM 1089 C CD  . LYS B 2 18  ? 381.481 396.092 500.673 1.00 115.08 ? 18  LYS L CD  1 
ATOM 1090 C CE  . LYS B 2 18  ? 382.378 397.014 499.870 1.00 115.08 ? 18  LYS L CE  1 
ATOM 1091 N NZ  . LYS B 2 18  ? 383.669 396.371 499.505 1.00 115.08 ? 18  LYS L NZ  1 
ATOM 1092 N N   . VAL B 2 19  ? 379.627 395.171 504.005 1.00 110.70 ? 19  VAL L N   1 
ATOM 1093 C CA  . VAL B 2 19  ? 380.127 393.883 504.457 1.00 110.70 ? 19  VAL L CA  1 
ATOM 1094 C C   . VAL B 2 19  ? 379.554 392.805 503.541 1.00 110.70 ? 19  VAL L C   1 
ATOM 1095 O O   . VAL B 2 19  ? 378.474 392.953 502.967 1.00 110.70 ? 19  VAL L O   1 
ATOM 1096 C CB  . VAL B 2 19  ? 379.778 393.626 505.944 1.00 110.70 ? 19  VAL L CB  1 
ATOM 1097 C CG1 . VAL B 2 19  ? 378.287 393.406 506.152 1.00 110.70 ? 19  VAL L CG1 1 
ATOM 1098 C CG2 . VAL B 2 19  ? 380.644 392.525 506.559 1.00 110.70 ? 19  VAL L CG2 1 
ATOM 1099 N N   . THR B 2 20  ? 380.318 391.729 503.366 1.00 107.01 ? 20  THR L N   1 
ATOM 1100 C CA  . THR B 2 20  ? 379.937 390.685 502.429 1.00 107.01 ? 20  THR L CA  1 
ATOM 1101 C C   . THR B 2 20  ? 380.293 389.312 502.981 1.00 107.01 ? 20  THR L C   1 
ATOM 1102 O O   . THR B 2 20  ? 381.155 389.176 503.854 1.00 107.01 ? 20  THR L O   1 
ATOM 1103 C CB  . THR B 2 20  ? 380.597 390.890 501.064 1.00 107.01 ? 20  THR L CB  1 
ATOM 1104 O OG1 . THR B 2 20  ? 380.092 389.916 500.147 1.00 107.01 ? 20  THR L OG1 1 
ATOM 1105 C CG2 . THR B 2 20  ? 382.099 390.757 501.161 1.00 107.01 ? 20  THR L CG2 1 
ATOM 1106 N N   . MET B 2 21  ? 379.607 388.295 502.460 1.00 101.78 ? 21  MET L N   1 
ATOM 1107 C CA  . MET B 2 21  ? 379.771 386.913 502.885 1.00 101.78 ? 21  MET L CA  1 
ATOM 1108 C C   . MET B 2 21  ? 379.799 386.012 501.661 1.00 101.78 ? 21  MET L C   1 
ATOM 1109 O O   . MET B 2 21  ? 379.261 386.356 500.610 1.00 101.78 ? 21  MET L O   1 
ATOM 1110 C CB  . MET B 2 21  ? 378.643 386.486 503.822 1.00 101.78 ? 21  MET L CB  1 
ATOM 1111 C CG  . MET B 2 21  ? 377.272 386.716 503.255 1.00 101.78 ? 21  MET L CG  1 
ATOM 1112 S SD  . MET B 2 21  ? 376.021 386.819 504.535 1.00 101.78 ? 21  MET L SD  1 
ATOM 1113 C CE  . MET B 2 21  ? 376.423 388.406 505.234 1.00 101.78 ? 21  MET L CE  1 
ATOM 1114 N N   . THR B 2 22  ? 380.429 384.850 501.802 1.00 100.33 ? 22  THR L N   1 
ATOM 1115 C CA  . THR B 2 22  ? 380.592 383.937 500.682 1.00 100.33 ? 22  THR L CA  1 
ATOM 1116 C C   . THR B 2 22  ? 380.149 382.525 501.045 1.00 100.33 ? 22  THR L C   1 
ATOM 1117 O O   . THR B 2 22  ? 380.069 382.151 502.218 1.00 100.33 ? 22  THR L O   1 
ATOM 1118 C CB  . THR B 2 22  ? 382.038 383.912 500.182 1.00 100.33 ? 22  THR L CB  1 
ATOM 1119 O OG1 . THR B 2 22  ? 382.129 383.044 499.049 1.00 100.33 ? 22  THR L OG1 1 
ATOM 1120 C CG2 . THR B 2 22  ? 382.974 383.422 501.257 1.00 100.33 ? 22  THR L CG2 1 
ATOM 1121 N N   . CYS B 2 23  ? 379.861 381.743 500.004 1.00 99.13  ? 23  CYS L N   1 
ATOM 1122 C CA  . CYS B 2 23  ? 379.265 380.415 500.135 1.00 99.13  ? 23  CYS L CA  1 
ATOM 1123 C C   . CYS B 2 23  ? 379.866 379.543 499.042 1.00 99.13  ? 23  CYS L C   1 
ATOM 1124 O O   . CYS B 2 23  ? 379.389 379.557 497.907 1.00 99.13  ? 23  CYS L O   1 
ATOM 1125 C CB  . CYS B 2 23  ? 377.738 380.494 500.022 1.00 99.13  ? 23  CYS L CB  1 
ATOM 1126 S SG  . CYS B 2 23  ? 376.816 378.943 499.833 1.00 99.13  ? 23  CYS L SG  1 
ATOM 1127 N N   . ARG B 2 24  ? 380.912 378.796 499.379 1.00 98.79  ? 24  ARG L N   1 
ATOM 1128 C CA  . ARG B 2 24  ? 381.698 378.047 498.409 1.00 98.79  ? 24  ARG L CA  1 
ATOM 1129 C C   . ARG B 2 24  ? 381.267 376.588 498.377 1.00 98.79  ? 24  ARG L C   1 
ATOM 1130 O O   . ARG B 2 24  ? 381.348 375.884 499.386 1.00 98.79  ? 24  ARG L O   1 
ATOM 1131 C CB  . ARG B 2 24  ? 383.184 378.131 498.742 1.00 98.79  ? 24  ARG L CB  1 
ATOM 1132 C CG  . ARG B 2 24  ? 384.101 377.699 497.617 1.00 98.79  ? 24  ARG L CG  1 
ATOM 1133 C CD  . ARG B 2 24  ? 385.538 378.118 497.878 1.00 98.79  ? 24  ARG L CD  1 
ATOM 1134 N NE  . ARG B 2 24  ? 385.700 379.568 497.843 1.00 98.79  ? 24  ARG L NE  1 
ATOM 1135 C CZ  . ARG B 2 24  ? 385.925 380.318 498.917 1.00 98.79  ? 24  ARG L CZ  1 
ATOM 1136 N NH1 . ARG B 2 24  ? 386.013 379.750 500.111 1.00 98.79  ? 24  ARG L NH1 1 
ATOM 1137 N NH2 . ARG B 2 24  ? 386.058 381.630 498.800 1.00 98.79  ? 24  ARG L NH2 1 
ATOM 1138 N N   . ALA B 2 25  ? 380.843 376.134 497.205 1.00 97.18  ? 25  ALA L N   1 
ATOM 1139 C CA  . ALA B 2 25  ? 380.328 374.788 497.012 1.00 97.18  ? 25  ALA L CA  1 
ATOM 1140 C C   . ALA B 2 25  ? 381.462 373.803 496.789 1.00 97.18  ? 25  ALA L C   1 
ATOM 1141 O O   . ALA B 2 25  ? 382.562 374.171 496.374 1.00 97.18  ? 25  ALA L O   1 
ATOM 1142 C CB  . ALA B 2 25  ? 379.372 374.744 495.821 1.00 97.18  ? 25  ALA L CB  1 
ATOM 1143 N N   . SER B 2 26  ? 381.176 372.530 497.059 1.00 95.17  ? 26  SER L N   1 
ATOM 1144 C CA  . SER B 2 26  ? 382.186 371.501 496.849 1.00 95.17  ? 26  SER L CA  1 
ATOM 1145 C C   . SER B 2 26  ? 382.404 371.234 495.368 1.00 95.17  ? 26  SER L C   1 
ATOM 1146 O O   . SER B 2 26  ? 383.547 371.135 494.915 1.00 95.17  ? 26  SER L O   1 
ATOM 1147 C CB  . SER B 2 26  ? 381.785 370.213 497.561 1.00 95.17  ? 26  SER L CB  1 
ATOM 1148 O OG  . SER B 2 26  ? 381.015 369.392 496.708 1.00 95.17  ? 26  SER L OG  1 
ATOM 1149 N N   . SER B 2 27  ? 381.325 371.126 494.605 1.00 94.41  ? 27  SER L N   1 
ATOM 1150 C CA  . SER B 2 27  ? 381.362 370.885 493.171 1.00 94.41  ? 27  SER L CA  1 
ATOM 1151 C C   . SER B 2 27  ? 380.711 372.056 492.448 1.00 94.41  ? 27  SER L C   1 
ATOM 1152 O O   . SER B 2 27  ? 380.418 373.093 493.039 1.00 94.41  ? 27  SER L O   1 
ATOM 1153 C CB  . SER B 2 27  ? 380.666 369.570 492.825 1.00 94.41  ? 27  SER L CB  1 
ATOM 1154 O OG  . SER B 2 27  ? 379.487 369.418 493.587 1.00 94.41  ? 27  SER L OG  1 
ATOM 1155 N N   . SER B 2 28  ? 380.493 371.888 491.153 1.00 89.68  ? 28  SER L N   1 
ATOM 1156 C CA  . SER B 2 28  ? 379.920 372.952 490.343 1.00 89.68  ? 28  SER L CA  1 
ATOM 1157 C C   . SER B 2 28  ? 378.408 372.974 490.506 1.00 89.68  ? 28  SER L C   1 
ATOM 1158 O O   . SER B 2 28  ? 377.739 371.967 490.265 1.00 89.68  ? 28  SER L O   1 
ATOM 1159 C CB  . SER B 2 28  ? 380.296 372.758 488.879 1.00 89.68  ? 28  SER L CB  1 
ATOM 1160 O OG  . SER B 2 28  ? 379.682 373.741 488.069 1.00 89.68  ? 28  SER L OG  1 
ATOM 1161 N N   . VAL B 2 29  ? 377.870 374.115 490.911 1.00 82.79  ? 29  VAL L N   1 
ATOM 1162 C CA  . VAL B 2 29  ? 376.431 374.330 490.972 1.00 82.79  ? 29  VAL L CA  1 
ATOM 1163 C C   . VAL B 2 29  ? 376.077 375.409 489.956 1.00 82.79  ? 29  VAL L C   1 
ATOM 1164 O O   . VAL B 2 29  ? 376.832 376.371 489.769 1.00 82.79  ? 29  VAL L O   1 
ATOM 1165 C CB  . VAL B 2 29  ? 375.976 374.681 492.408 1.00 82.79  ? 29  VAL L CB  1 
ATOM 1166 C CG1 . VAL B 2 29  ? 376.715 375.876 492.952 1.00 82.79  ? 29  VAL L CG1 1 
ATOM 1167 C CG2 . VAL B 2 29  ? 374.480 374.900 492.494 1.00 82.79  ? 29  VAL L CG2 1 
ATOM 1168 N N   . SER B 2 30  ? 374.973 375.205 489.241 1.00 79.36  ? 30  SER L N   1 
ATOM 1169 C CA  . SER B 2 30  ? 374.554 376.143 488.215 1.00 79.36  ? 30  SER L CA  1 
ATOM 1170 C C   . SER B 2 30  ? 374.130 377.463 488.834 1.00 79.36  ? 30  SER L C   1 
ATOM 1171 O O   . SER B 2 30  ? 373.748 377.532 490.001 1.00 79.36  ? 30  SER L O   1 
ATOM 1172 C CB  . SER B 2 30  ? 373.403 375.572 487.405 1.00 79.36  ? 30  SER L CB  1 
ATOM 1173 O OG  . SER B 2 30  ? 372.688 376.619 486.784 1.00 79.36  ? 30  SER L OG  1 
ATOM 1174 N N   . SER B 2 31  ? 374.197 378.520 488.032 1.00 77.98  ? 31  SER L N   1 
ATOM 1175 C CA  . SER B 2 31  ? 373.959 379.860 488.544 1.00 77.98  ? 31  SER L CA  1 
ATOM 1176 C C   . SER B 2 31  ? 372.502 380.121 488.851 1.00 77.98  ? 31  SER L C   1 
ATOM 1177 O O   . SER B 2 31  ? 372.205 381.034 489.619 1.00 77.98  ? 31  SER L O   1 
ATOM 1178 C CB  . SER B 2 31  ? 374.441 380.902 487.544 1.00 77.98  ? 31  SER L CB  1 
ATOM 1179 O OG  . SER B 2 31  ? 373.635 380.884 486.384 1.00 77.98  ? 31  SER L OG  1 
ATOM 1180 N N   . SER B 2 32  ? 371.591 379.353 488.275 1.00 74.75  ? 32  SER L N   1 
ATOM 1181 C CA  . SER B 2 32  ? 370.174 379.589 488.481 1.00 74.75  ? 32  SER L CA  1 
ATOM 1182 C C   . SER B 2 32  ? 369.623 378.854 489.682 1.00 74.75  ? 32  SER L C   1 
ATOM 1183 O O   . SER B 2 32  ? 368.527 379.181 490.137 1.00 74.75  ? 32  SER L O   1 
ATOM 1184 C CB  . SER B 2 32  ? 369.390 379.172 487.255 1.00 74.75  ? 32  SER L CB  1 
ATOM 1185 O OG  . SER B 2 32  ? 369.044 377.812 487.339 1.00 74.75  ? 32  SER L OG  1 
ATOM 1186 N N   . TYR B 2 33  ? 370.350 377.875 490.205 1.00 74.71  ? 33  TYR L N   1 
ATOM 1187 C CA  . TYR B 2 33  ? 369.860 377.045 491.293 1.00 74.71  ? 33  TYR L CA  1 
ATOM 1188 C C   . TYR B 2 33  ? 370.522 377.381 492.617 1.00 74.71  ? 33  TYR L C   1 
ATOM 1189 O O   . TYR B 2 33  ? 370.676 376.496 493.456 1.00 74.71  ? 33  TYR L O   1 
ATOM 1190 C CB  . TYR B 2 33  ? 370.080 375.568 490.985 1.00 74.71  ? 33  TYR L CB  1 
ATOM 1191 C CG  . TYR B 2 33  ? 369.320 375.050 489.804 1.00 74.71  ? 33  TYR L CG  1 
ATOM 1192 C CD1 . TYR B 2 33  ? 367.974 375.297 489.661 1.00 74.71  ? 33  TYR L CD1 1 
ATOM 1193 C CD2 . TYR B 2 33  ? 369.953 374.297 488.835 1.00 74.71  ? 33  TYR L CD2 1 
ATOM 1194 C CE1 . TYR B 2 33  ? 367.278 374.813 488.582 1.00 74.71  ? 33  TYR L CE1 1 
ATOM 1195 C CE2 . TYR B 2 33  ? 369.268 373.812 487.757 1.00 74.71  ? 33  TYR L CE2 1 
ATOM 1196 C CZ  . TYR B 2 33  ? 367.934 374.073 487.637 1.00 74.71  ? 33  TYR L CZ  1 
ATOM 1197 O OH  . TYR B 2 33  ? 367.246 373.591 486.558 1.00 74.71  ? 33  TYR L OH  1 
ATOM 1198 N N   . LEU B 2 34  ? 370.939 378.625 492.828 1.00 78.20  ? 34  LEU L N   1 
ATOM 1199 C CA  . LEU B 2 34  ? 371.502 379.030 494.109 1.00 78.20  ? 34  LEU L CA  1 
ATOM 1200 C C   . LEU B 2 34  ? 370.734 380.229 494.640 1.00 78.20  ? 34  LEU L C   1 
ATOM 1201 O O   . LEU B 2 34  ? 370.615 381.247 493.956 1.00 78.20  ? 34  LEU L O   1 
ATOM 1202 C CB  . LEU B 2 34  ? 372.994 379.323 493.991 1.00 78.20  ? 34  LEU L CB  1 
ATOM 1203 C CG  . LEU B 2 34  ? 373.686 379.451 495.342 1.00 78.20  ? 34  LEU L CG  1 
ATOM 1204 C CD1 . LEU B 2 34  ? 374.981 378.703 495.302 1.00 78.20  ? 34  LEU L CD1 1 
ATOM 1205 C CD2 . LEU B 2 34  ? 373.978 380.899 495.659 1.00 78.20  ? 34  LEU L CD2 1 
ATOM 1206 N N   . HIS B 2 35  ? 370.232 380.108 495.862 1.00 79.25  ? 35  HIS L N   1 
ATOM 1207 C CA  . HIS B 2 35  ? 369.330 381.074 496.458 1.00 79.25  ? 35  HIS L CA  1 
ATOM 1208 C C   . HIS B 2 35  ? 369.847 381.485 497.828 1.00 79.25  ? 35  HIS L C   1 
ATOM 1209 O O   . HIS B 2 35  ? 370.686 380.813 498.421 1.00 79.25  ? 35  HIS L O   1 
ATOM 1210 C CB  . HIS B 2 35  ? 367.926 380.484 496.585 1.00 79.25  ? 35  HIS L CB  1 
ATOM 1211 C CG  . HIS B 2 35  ? 367.470 379.738 495.371 1.00 79.25  ? 35  HIS L CG  1 
ATOM 1212 N ND1 . HIS B 2 35  ? 366.997 380.366 494.243 1.00 79.25  ? 35  HIS L ND1 1 
ATOM 1213 C CD2 . HIS B 2 35  ? 367.418 378.413 495.110 1.00 79.25  ? 35  HIS L CD2 1 
ATOM 1214 C CE1 . HIS B 2 35  ? 366.666 379.461 493.342 1.00 79.25  ? 35  HIS L CE1 1 
ATOM 1215 N NE2 . HIS B 2 35  ? 366.915 378.268 493.843 1.00 79.25  ? 35  HIS L NE2 1 
ATOM 1216 N N   . TRP B 2 36  ? 369.327 382.595 498.341 1.00 87.03  ? 36  TRP L N   1 
ATOM 1217 C CA  . TRP B 2 36  ? 369.699 383.106 499.653 1.00 87.03  ? 36  TRP L CA  1 
ATOM 1218 C C   . TRP B 2 36  ? 368.446 383.350 500.477 1.00 87.03  ? 36  TRP L C   1 
ATOM 1219 O O   . TRP B 2 36  ? 367.459 383.881 499.969 1.00 87.03  ? 36  TRP L O   1 
ATOM 1220 C CB  . TRP B 2 36  ? 370.486 384.408 499.550 1.00 87.03  ? 36  TRP L CB  1 
ATOM 1221 C CG  . TRP B 2 36  ? 371.856 384.262 499.007 1.00 87.03  ? 36  TRP L CG  1 
ATOM 1222 C CD1 . TRP B 2 36  ? 372.226 384.337 497.705 1.00 87.03  ? 36  TRP L CD1 1 
ATOM 1223 C CD2 . TRP B 2 36  ? 373.051 384.033 499.751 1.00 87.03  ? 36  TRP L CD2 1 
ATOM 1224 N NE1 . TRP B 2 36  ? 373.577 384.157 497.585 1.00 87.03  ? 36  TRP L NE1 1 
ATOM 1225 C CE2 . TRP B 2 36  ? 374.107 383.969 498.832 1.00 87.03  ? 36  TRP L CE2 1 
ATOM 1226 C CE3 . TRP B 2 36  ? 373.331 383.873 501.105 1.00 87.03  ? 36  TRP L CE3 1 
ATOM 1227 C CZ2 . TRP B 2 36  ? 375.419 383.754 499.224 1.00 87.03  ? 36  TRP L CZ2 1 
ATOM 1228 C CZ3 . TRP B 2 36  ? 374.633 383.656 501.488 1.00 87.03  ? 36  TRP L CZ3 1 
ATOM 1229 C CH2 . TRP B 2 36  ? 375.659 383.597 500.555 1.00 87.03  ? 36  TRP L CH2 1 
ATOM 1230 N N   . TYR B 2 37  ? 368.494 382.979 501.750 1.00 86.25  ? 37  TYR L N   1 
ATOM 1231 C CA  . TYR B 2 37  ? 367.369 383.125 502.660 1.00 86.25  ? 37  TYR L CA  1 
ATOM 1232 C C   . TYR B 2 37  ? 367.788 383.968 503.855 1.00 86.25  ? 37  TYR L C   1 
ATOM 1233 O O   . TYR B 2 37  ? 368.968 384.243 504.060 1.00 86.25  ? 37  TYR L O   1 
ATOM 1234 C CB  . TYR B 2 37  ? 366.864 381.762 503.136 1.00 86.25  ? 37  TYR L CB  1 
ATOM 1235 C CG  . TYR B 2 37  ? 366.273 380.902 502.053 1.00 86.25  ? 37  TYR L CG  1 
ATOM 1236 C CD1 . TYR B 2 37  ? 367.073 380.087 501.277 1.00 86.25  ? 37  TYR L CD1 1 
ATOM 1237 C CD2 . TYR B 2 37  ? 364.913 380.891 501.822 1.00 86.25  ? 37  TYR L CD2 1 
ATOM 1238 C CE1 . TYR B 2 37  ? 366.538 379.299 500.289 1.00 86.25  ? 37  TYR L CE1 1 
ATOM 1239 C CE2 . TYR B 2 37  ? 364.370 380.102 500.840 1.00 86.25  ? 37  TYR L CE2 1 
ATOM 1240 C CZ  . TYR B 2 37  ? 365.188 379.313 500.077 1.00 86.25  ? 37  TYR L CZ  1 
ATOM 1241 O OH  . TYR B 2 37  ? 364.652 378.526 499.094 1.00 86.25  ? 37  TYR L OH  1 
ATOM 1242 N N   . GLN B 2 38  ? 366.810 384.374 504.661 1.00 92.58  ? 38  GLN L N   1 
ATOM 1243 C CA  . GLN B 2 38  ? 367.079 385.171 505.852 1.00 92.58  ? 38  GLN L CA  1 
ATOM 1244 C C   . GLN B 2 38  ? 366.147 384.744 506.970 1.00 92.58  ? 38  GLN L C   1 
ATOM 1245 O O   . GLN B 2 38  ? 364.927 384.825 506.824 1.00 92.58  ? 38  GLN L O   1 
ATOM 1246 C CB  . GLN B 2 38  ? 366.910 386.663 505.580 1.00 92.58  ? 38  GLN L CB  1 
ATOM 1247 C CG  . GLN B 2 38  ? 366.951 387.494 506.846 1.00 92.58  ? 38  GLN L CG  1 
ATOM 1248 C CD  . GLN B 2 38  ? 366.450 388.895 506.645 1.00 92.58  ? 38  GLN L CD  1 
ATOM 1249 O OE1 . GLN B 2 38  ? 365.255 389.156 506.739 1.00 92.58  ? 38  GLN L OE1 1 
ATOM 1250 N NE2 . GLN B 2 38  ? 367.363 389.814 506.373 1.00 92.58  ? 38  GLN L NE2 1 
ATOM 1251 N N   . GLN B 2 39  ? 366.718 384.313 508.088 1.00 98.84  ? 39  GLN L N   1 
ATOM 1252 C CA  . GLN B 2 39  ? 365.954 383.876 509.248 1.00 98.84  ? 39  GLN L CA  1 
ATOM 1253 C C   . GLN B 2 39  ? 366.333 384.727 510.449 1.00 98.84  ? 39  GLN L C   1 
ATOM 1254 O O   . GLN B 2 39  ? 367.469 384.658 510.927 1.00 98.84  ? 39  GLN L O   1 
ATOM 1255 C CB  . GLN B 2 39  ? 366.204 382.403 509.556 1.00 98.84  ? 39  GLN L CB  1 
ATOM 1256 C CG  . GLN B 2 39  ? 365.487 381.936 510.798 1.00 98.84  ? 39  GLN L CG  1 
ATOM 1257 C CD  . GLN B 2 39  ? 365.684 380.469 511.074 1.00 98.84  ? 39  GLN L CD  1 
ATOM 1258 O OE1 . GLN B 2 39  ? 366.725 379.904 510.757 1.00 98.84  ? 39  GLN L OE1 1 
ATOM 1259 N NE2 . GLN B 2 39  ? 364.681 379.838 511.665 1.00 98.84  ? 39  GLN L NE2 1 
ATOM 1260 N N   . LYS B 2 40  ? 365.380 385.509 510.944 1.00 103.47 ? 40  LYS L N   1 
ATOM 1261 C CA  . LYS B 2 40  ? 365.587 386.282 512.154 1.00 103.47 ? 40  LYS L CA  1 
ATOM 1262 C C   . LYS B 2 40  ? 365.463 385.371 513.369 1.00 103.47 ? 40  LYS L C   1 
ATOM 1263 O O   . LYS B 2 40  ? 365.143 384.187 513.261 1.00 103.47 ? 40  LYS L O   1 
ATOM 1264 C CB  . LYS B 2 40  ? 364.599 387.439 512.213 1.00 103.47 ? 40  LYS L CB  1 
ATOM 1265 C CG  . LYS B 2 40  ? 365.009 388.596 511.334 1.00 103.47 ? 40  LYS L CG  1 
ATOM 1266 C CD  . LYS B 2 40  ? 364.078 389.772 511.443 1.00 103.47 ? 40  LYS L CD  1 
ATOM 1267 C CE  . LYS B 2 40  ? 364.595 390.913 510.600 1.00 103.47 ? 40  LYS L CE  1 
ATOM 1268 N NZ  . LYS B 2 40  ? 363.615 392.022 510.510 1.00 103.47 ? 40  LYS L NZ  1 
ATOM 1269 N N   . SER B 2 41  ? 365.726 385.917 514.549 1.00 106.51 ? 41  SER L N   1 
ATOM 1270 C CA  . SER B 2 41  ? 365.660 385.112 515.762 1.00 106.51 ? 41  SER L CA  1 
ATOM 1271 C C   . SER B 2 41  ? 364.202 384.921 516.150 1.00 106.51 ? 41  SER L C   1 
ATOM 1272 O O   . SER B 2 41  ? 363.468 385.895 516.338 1.00 106.51 ? 41  SER L O   1 
ATOM 1273 C CB  . SER B 2 41  ? 366.449 385.773 516.886 1.00 106.51 ? 41  SER L CB  1 
ATOM 1274 O OG  . SER B 2 41  ? 366.377 385.005 518.073 1.00 106.51 ? 41  SER L OG  1 
ATOM 1275 N N   . GLY B 2 42  ? 363.776 383.667 516.252 1.00 105.08 ? 42  GLY L N   1 
ATOM 1276 C CA  . GLY B 2 42  ? 362.399 383.383 516.596 1.00 105.08 ? 42  GLY L CA  1 
ATOM 1277 C C   . GLY B 2 42  ? 361.415 383.663 515.487 1.00 105.08 ? 42  GLY L C   1 
ATOM 1278 O O   . GLY B 2 42  ? 360.309 384.138 515.756 1.00 105.08 ? 42  GLY L O   1 
ATOM 1279 N N   . ALA B 2 43  ? 361.791 383.395 514.241 1.00 101.16 ? 43  ALA L N   1 
ATOM 1280 C CA  . ALA B 2 43  ? 360.902 383.565 513.104 1.00 101.16 ? 43  ALA L CA  1 
ATOM 1281 C C   . ALA B 2 43  ? 361.280 382.581 512.008 1.00 101.16 ? 43  ALA L C   1 
ATOM 1282 O O   . ALA B 2 43  ? 362.380 382.027 511.985 1.00 101.16 ? 43  ALA L O   1 
ATOM 1283 C CB  . ALA B 2 43  ? 360.942 384.999 512.568 1.00 101.16 ? 43  ALA L CB  1 
ATOM 1284 N N   . SER B 2 44  ? 360.339 382.366 511.098 1.00 97.66  ? 44  SER L N   1 
ATOM 1285 C CA  . SER B 2 44  ? 360.563 381.490 509.963 1.00 97.66  ? 44  SER L CA  1 
ATOM 1286 C C   . SER B 2 44  ? 361.466 382.182 508.944 1.00 97.66  ? 44  SER L C   1 
ATOM 1287 O O   . SER B 2 44  ? 361.577 383.409 508.944 1.00 97.66  ? 44  SER L O   1 
ATOM 1288 C CB  . SER B 2 44  ? 359.226 381.126 509.329 1.00 97.66  ? 44  SER L CB  1 
ATOM 1289 O OG  . SER B 2 44  ? 358.387 382.262 509.250 1.00 97.66  ? 44  SER L OG  1 
ATOM 1290 N N   . PRO B 2 45  ? 362.146 381.424 508.086 1.00 92.44  ? 45  PRO L N   1 
ATOM 1291 C CA  . PRO B 2 45  ? 362.957 382.055 507.043 1.00 92.44  ? 45  PRO L CA  1 
ATOM 1292 C C   . PRO B 2 45  ? 362.100 382.733 505.990 1.00 92.44  ? 45  PRO L C   1 
ATOM 1293 O O   . PRO B 2 45  ? 360.889 382.535 505.903 1.00 92.44  ? 45  PRO L O   1 
ATOM 1294 C CB  . PRO B 2 45  ? 363.738 380.885 506.442 1.00 92.44  ? 45  PRO L CB  1 
ATOM 1295 C CG  . PRO B 2 45  ? 363.747 379.872 507.487 1.00 92.44  ? 45  PRO L CG  1 
ATOM 1296 C CD  . PRO B 2 45  ? 362.444 379.988 508.186 1.00 92.44  ? 45  PRO L CD  1 
ATOM 1297 N N   . LYS B 2 46  ? 362.753 383.574 505.197 1.00 89.06  ? 46  LYS L N   1 
ATOM 1298 C CA  . LYS B 2 46  ? 362.115 384.256 504.085 1.00 89.06  ? 46  LYS L CA  1 
ATOM 1299 C C   . LYS B 2 46  ? 363.051 384.191 502.894 1.00 89.06  ? 46  LYS L C   1 
ATOM 1300 O O   . LYS B 2 46  ? 364.267 384.297 503.048 1.00 89.06  ? 46  LYS L O   1 
ATOM 1301 C CB  . LYS B 2 46  ? 361.801 385.720 504.410 1.00 89.06  ? 46  LYS L CB  1 
ATOM 1302 C CG  . LYS B 2 46  ? 360.827 385.926 505.551 1.00 89.06  ? 46  LYS L CG  1 
ATOM 1303 C CD  . LYS B 2 46  ? 360.647 387.394 505.864 1.00 89.06  ? 46  LYS L CD  1 
ATOM 1304 C CE  . LYS B 2 46  ? 359.702 388.050 504.889 1.00 89.06  ? 46  LYS L CE  1 
ATOM 1305 N NZ  . LYS B 2 46  ? 358.304 387.621 505.153 1.00 89.06  ? 46  LYS L NZ  1 
ATOM 1306 N N   . LEU B 2 47  ? 362.485 384.007 501.707 1.00 84.86  ? 47  LEU L N   1 
ATOM 1307 C CA  . LEU B 2 47  ? 363.305 384.002 500.506 1.00 84.86  ? 47  LEU L CA  1 
ATOM 1308 C C   . LEU B 2 47  ? 363.795 385.410 500.226 1.00 84.86  ? 47  LEU L C   1 
ATOM 1309 O O   . LEU B 2 47  ? 363.007 386.356 500.190 1.00 84.86  ? 47  LEU L O   1 
ATOM 1310 C CB  . LEU B 2 47  ? 362.522 383.473 499.312 1.00 84.86  ? 47  LEU L CB  1 
ATOM 1311 C CG  . LEU B 2 47  ? 363.295 383.486 497.998 1.00 84.86  ? 47  LEU L CG  1 
ATOM 1312 C CD1 . LEU B 2 47  ? 364.306 382.381 497.984 1.00 84.86  ? 47  LEU L CD1 1 
ATOM 1313 C CD2 . LEU B 2 47  ? 362.369 383.355 496.824 1.00 84.86  ? 47  LEU L CD2 1 
ATOM 1314 N N   . TRP B 2 48  ? 365.100 385.552 500.033 1.00 88.22  ? 48  TRP L N   1 
ATOM 1315 C CA  . TRP B 2 48  ? 365.725 386.857 499.921 1.00 88.22  ? 48  TRP L CA  1 
ATOM 1316 C C   . TRP B 2 48  ? 366.215 387.129 498.506 1.00 88.22  ? 48  TRP L C   1 
ATOM 1317 O O   . TRP B 2 48  ? 365.845 388.135 497.902 1.00 88.22  ? 48  TRP L O   1 
ATOM 1318 C CB  . TRP B 2 48  ? 366.872 386.936 500.932 1.00 88.22  ? 48  TRP L CB  1 
ATOM 1319 C CG  . TRP B 2 48  ? 367.109 388.277 501.516 1.00 88.22  ? 48  TRP L CG  1 
ATOM 1320 C CD1 . TRP B 2 48  ? 368.215 389.044 501.364 1.00 88.22  ? 48  TRP L CD1 1 
ATOM 1321 C CD2 . TRP B 2 48  ? 366.220 389.013 502.362 1.00 88.22  ? 48  TRP L CD2 1 
ATOM 1322 N NE1 . TRP B 2 48  ? 368.075 390.215 502.059 1.00 88.22  ? 48  TRP L NE1 1 
ATOM 1323 C CE2 . TRP B 2 48  ? 366.858 390.217 502.685 1.00 88.22  ? 48  TRP L CE2 1 
ATOM 1324 C CE3 . TRP B 2 48  ? 364.949 388.768 502.881 1.00 88.22  ? 48  TRP L CE3 1 
ATOM 1325 C CZ2 . TRP B 2 48  ? 366.266 391.178 503.490 1.00 88.22  ? 48  TRP L CZ2 1 
ATOM 1326 C CZ3 . TRP B 2 48  ? 364.367 389.718 503.679 1.00 88.22  ? 48  TRP L CZ3 1 
ATOM 1327 C CH2 . TRP B 2 48  ? 365.021 390.908 503.976 1.00 88.22  ? 48  TRP L CH2 1 
ATOM 1328 N N   . ILE B 2 49  ? 367.031 386.242 497.952 1.00 82.20  ? 49  ILE L N   1 
ATOM 1329 C CA  . ILE B 2 49  ? 367.562 386.379 496.605 1.00 82.20  ? 49  ILE L CA  1 
ATOM 1330 C C   . ILE B 2 49  ? 367.433 385.022 495.936 1.00 82.20  ? 49  ILE L C   1 
ATOM 1331 O O   . ILE B 2 49  ? 367.821 384.008 496.521 1.00 82.20  ? 49  ILE L O   1 
ATOM 1332 C CB  . ILE B 2 49  ? 369.023 386.855 496.626 1.00 82.20  ? 49  ILE L CB  1 
ATOM 1333 C CG1 . ILE B 2 49  ? 369.075 388.362 496.863 1.00 82.20  ? 49  ILE L CG1 1 
ATOM 1334 C CG2 . ILE B 2 49  ? 369.762 386.479 495.353 1.00 82.20  ? 49  ILE L CG2 1 
ATOM 1335 C CD1 . ILE B 2 49  ? 370.458 388.922 496.882 1.00 82.20  ? 49  ILE L CD1 1 
ATOM 1336 N N   . TYR B 2 50  ? 366.860 384.988 494.737 1.00 77.71  ? 50  TYR L N   1 
ATOM 1337 C CA  . TYR B 2 50  ? 366.732 383.740 494.006 1.00 77.71  ? 50  TYR L CA  1 
ATOM 1338 C C   . TYR B 2 50  ? 367.545 383.780 492.721 1.00 77.71  ? 50  TYR L C   1 
ATOM 1339 O O   . TYR B 2 50  ? 367.638 384.817 492.063 1.00 77.71  ? 50  TYR L O   1 
ATOM 1340 C CB  . TYR B 2 50  ? 365.267 383.416 493.705 1.00 77.71  ? 50  TYR L CB  1 
ATOM 1341 C CG  . TYR B 2 50  ? 364.567 384.324 492.736 1.00 77.71  ? 50  TYR L CG  1 
ATOM 1342 C CD1 . TYR B 2 50  ? 363.978 385.495 493.162 1.00 77.71  ? 50  TYR L CD1 1 
ATOM 1343 C CD2 . TYR B 2 50  ? 364.453 383.984 491.397 1.00 77.71  ? 50  TYR L CD2 1 
ATOM 1344 C CE1 . TYR B 2 50  ? 363.322 386.318 492.278 1.00 77.71  ? 50  TYR L CE1 1 
ATOM 1345 C CE2 . TYR B 2 50  ? 363.804 384.804 490.508 1.00 77.71  ? 50  TYR L CE2 1 
ATOM 1346 C CZ  . TYR B 2 50  ? 363.243 385.964 490.955 1.00 77.71  ? 50  TYR L CZ  1 
ATOM 1347 O OH  . TYR B 2 50  ? 362.596 386.776 490.065 1.00 77.71  ? 50  TYR L OH  1 
ATOM 1348 N N   . SER B 2 51  ? 368.141 382.628 492.396 1.00 78.45  ? 51  SER L N   1 
ATOM 1349 C CA  . SER B 2 51  ? 368.949 382.406 491.192 1.00 78.45  ? 51  SER L CA  1 
ATOM 1350 C C   . SER B 2 51  ? 370.132 383.359 491.114 1.00 78.45  ? 51  SER L C   1 
ATOM 1351 O O   . SER B 2 51  ? 370.402 383.940 490.066 1.00 78.45  ? 51  SER L O   1 
ATOM 1352 C CB  . SER B 2 51  ? 368.102 382.486 489.925 1.00 78.45  ? 51  SER L CB  1 
ATOM 1353 O OG  . SER B 2 51  ? 367.484 381.243 489.672 1.00 78.45  ? 51  SER L OG  1 
ATOM 1354 N N   . THR B 2 52  ? 370.749 383.600 492.273 1.00 83.64  ? 52  THR L N   1 
ATOM 1355 C CA  . THR B 2 52  ? 372.039 384.228 492.587 1.00 83.64  ? 52  THR L CA  1 
ATOM 1356 C C   . THR B 2 52  ? 372.149 385.703 492.227 1.00 83.64  ? 52  THR L C   1 
ATOM 1357 O O   . THR B 2 52  ? 373.129 386.349 492.601 1.00 83.64  ? 52  THR L O   1 
ATOM 1358 C CB  . THR B 2 52  ? 373.239 383.494 491.967 1.00 83.64  ? 52  THR L CB  1 
ATOM 1359 O OG1 . THR B 2 52  ? 374.408 383.925 492.658 1.00 83.64  ? 52  THR L OG1 1 
ATOM 1360 C CG2 . THR B 2 52  ? 373.511 383.882 490.527 1.00 83.64  ? 52  THR L CG2 1 
ATOM 1361 N N   . SER B 2 53  ? 371.162 386.268 491.552 1.00 80.62  ? 53  SER L N   1 
ATOM 1362 C CA  . SER B 2 53  ? 371.254 387.671 491.196 1.00 80.62  ? 53  SER L CA  1 
ATOM 1363 C C   . SER B 2 53  ? 369.948 388.433 491.305 1.00 80.62  ? 53  SER L C   1 
ATOM 1364 O O   . SER B 2 53  ? 369.967 389.656 491.158 1.00 80.62  ? 53  SER L O   1 
ATOM 1365 C CB  . SER B 2 53  ? 371.782 387.808 489.767 1.00 80.62  ? 53  SER L CB  1 
ATOM 1366 O OG  . SER B 2 53  ? 373.069 387.240 489.647 1.00 80.62  ? 53  SER L OG  1 
ATOM 1367 N N   . ASN B 2 54  ? 368.828 387.775 491.570 1.00 80.19  ? 54  ASN L N   1 
ATOM 1368 C CA  . ASN B 2 54  ? 367.523 388.404 491.455 1.00 80.19  ? 54  ASN L CA  1 
ATOM 1369 C C   . ASN B 2 54  ? 366.909 388.604 492.826 1.00 80.19  ? 54  ASN L C   1 
ATOM 1370 O O   . ASN B 2 54  ? 366.728 387.648 493.580 1.00 80.19  ? 54  ASN L O   1 
ATOM 1371 C CB  . ASN B 2 54  ? 366.585 387.572 490.589 1.00 80.19  ? 54  ASN L CB  1 
ATOM 1372 C CG  . ASN B 2 54  ? 367.129 387.347 489.207 1.00 80.19  ? 54  ASN L CG  1 
ATOM 1373 O OD1 . ASN B 2 54  ? 367.042 388.216 488.345 1.00 80.19  ? 54  ASN L OD1 1 
ATOM 1374 N ND2 . ASN B 2 54  ? 367.699 386.178 488.984 1.00 80.19  ? 54  ASN L ND2 1 
ATOM 1375 N N   . LEU B 2 55  ? 366.580 389.849 493.132 1.00 83.57  ? 55  LEU L N   1 
ATOM 1376 C CA  . LEU B 2 55  ? 365.977 390.184 494.406 1.00 83.57  ? 55  LEU L CA  1 
ATOM 1377 C C   . LEU B 2 55  ? 364.540 389.699 494.446 1.00 83.57  ? 55  LEU L C   1 
ATOM 1378 O O   . LEU B 2 55  ? 363.831 389.715 493.441 1.00 83.57  ? 55  LEU L O   1 
ATOM 1379 C CB  . LEU B 2 55  ? 366.019 391.691 494.634 1.00 83.57  ? 55  LEU L CB  1 
ATOM 1380 C CG  . LEU B 2 55  ? 367.160 392.252 495.479 1.00 83.57  ? 55  LEU L CG  1 
ATOM 1381 C CD1 . LEU B 2 55  ? 368.473 392.178 494.734 1.00 83.57  ? 55  LEU L CD1 1 
ATOM 1382 C CD2 . LEU B 2 55  ? 366.852 393.678 495.861 1.00 83.57  ? 55  LEU L CD2 1 
ATOM 1383 N N   . ALA B 2 56  ? 364.104 389.281 495.626 1.00 88.60  ? 56  ALA L N   1 
ATOM 1384 C CA  . ALA B 2 56  ? 362.754 388.767 495.793 1.00 88.60  ? 56  ALA L CA  1 
ATOM 1385 C C   . ALA B 2 56  ? 361.768 389.925 495.896 1.00 88.60  ? 56  ALA L C   1 
ATOM 1386 O O   . ALA B 2 56  ? 362.086 391.082 495.613 1.00 88.60  ? 56  ALA L O   1 
ATOM 1387 C CB  . ALA B 2 56  ? 362.680 387.860 497.012 1.00 88.60  ? 56  ALA L CB  1 
ATOM 1388 N N   . SER B 2 57  ? 360.543 389.629 496.298 1.00 96.67  ? 57  SER L N   1 
ATOM 1389 C CA  . SER B 2 57  ? 359.535 390.662 496.454 1.00 96.67  ? 57  SER L CA  1 
ATOM 1390 C C   . SER B 2 57  ? 359.687 391.304 497.824 1.00 96.67  ? 57  SER L C   1 
ATOM 1391 O O   . SER B 2 57  ? 359.962 390.616 498.811 1.00 96.67  ? 57  SER L O   1 
ATOM 1392 C CB  . SER B 2 57  ? 358.132 390.083 496.288 1.00 96.67  ? 57  SER L CB  1 
ATOM 1393 O OG  . SER B 2 57  ? 357.994 388.868 497.001 1.00 96.67  ? 57  SER L OG  1 
ATOM 1394 N N   . GLY B 2 58  ? 359.533 392.622 497.876 1.00 97.99  ? 58  GLY L N   1 
ATOM 1395 C CA  . GLY B 2 58  ? 359.524 393.330 499.137 1.00 97.99  ? 58  GLY L CA  1 
ATOM 1396 C C   . GLY B 2 58  ? 360.862 393.465 499.819 1.00 97.99  ? 58  GLY L C   1 
ATOM 1397 O O   . GLY B 2 58  ? 360.902 393.861 500.987 1.00 97.99  ? 58  GLY L O   1 
ATOM 1398 N N   . VAL B 2 59  ? 361.956 393.147 499.141 1.00 94.82  ? 59  VAL L N   1 
ATOM 1399 C CA  . VAL B 2 59  ? 363.281 393.216 499.747 1.00 94.82  ? 59  VAL L CA  1 
ATOM 1400 C C   . VAL B 2 59  ? 363.928 394.540 499.344 1.00 94.82  ? 59  VAL L C   1 
ATOM 1401 O O   . VAL B 2 59  ? 363.725 395.008 498.215 1.00 94.82  ? 59  VAL L O   1 
ATOM 1402 C CB  . VAL B 2 59  ? 364.098 391.964 499.371 1.00 94.82  ? 59  VAL L CB  1 
ATOM 1403 C CG1 . VAL B 2 59  ? 364.311 391.873 497.906 1.00 94.82  ? 59  VAL L CG1 1 
ATOM 1404 C CG2 . VAL B 2 59  ? 365.430 391.944 500.043 1.00 94.82  ? 59  VAL L CG2 1 
ATOM 1405 N N   . PRO B 2 60  ? 364.621 395.227 500.252 1.00 98.70  ? 60  PRO L N   1 
ATOM 1406 C CA  . PRO B 2 60  ? 365.251 396.500 499.892 1.00 98.70  ? 60  PRO L CA  1 
ATOM 1407 C C   . PRO B 2 60  ? 366.444 396.312 498.973 1.00 98.70  ? 60  PRO L C   1 
ATOM 1408 O O   . PRO B 2 60  ? 367.059 395.250 498.910 1.00 98.70  ? 60  PRO L O   1 
ATOM 1409 C CB  . PRO B 2 60  ? 365.687 397.074 501.240 1.00 98.70  ? 60  PRO L CB  1 
ATOM 1410 C CG  . PRO B 2 60  ? 364.799 396.434 502.218 1.00 98.70  ? 60  PRO L CG  1 
ATOM 1411 C CD  . PRO B 2 60  ? 364.553 395.057 501.711 1.00 98.70  ? 60  PRO L CD  1 
ATOM 1412 N N   . ALA B 2 61  ? 366.789 397.393 498.282 1.00 100.70 ? 61  ALA L N   1 
ATOM 1413 C CA  . ALA B 2 61  ? 367.733 397.361 497.175 1.00 100.70 ? 61  ALA L CA  1 
ATOM 1414 C C   . ALA B 2 61  ? 369.191 397.408 497.613 1.00 100.70 ? 61  ALA L C   1 
ATOM 1415 O O   . ALA B 2 61  ? 370.069 397.606 496.770 1.00 100.70 ? 61  ALA L O   1 
ATOM 1416 C CB  . ALA B 2 61  ? 367.445 398.518 496.219 1.00 100.70 ? 61  ALA L CB  1 
ATOM 1417 N N   . ARG B 2 62  ? 369.472 397.226 498.901 1.00 104.85 ? 62  ARG L N   1 
ATOM 1418 C CA  . ARG B 2 62  ? 370.845 397.320 499.379 1.00 104.85 ? 62  ARG L CA  1 
ATOM 1419 C C   . ARG B 2 62  ? 371.652 396.072 499.059 1.00 104.85 ? 62  ARG L C   1 
ATOM 1420 O O   . ARG B 2 62  ? 372.885 396.115 499.093 1.00 104.85 ? 62  ARG L O   1 
ATOM 1421 C CB  . ARG B 2 62  ? 370.854 397.574 500.885 1.00 104.85 ? 62  ARG L CB  1 
ATOM 1422 C CG  . ARG B 2 62  ? 369.909 398.672 501.319 1.00 104.85 ? 62  ARG L CG  1 
ATOM 1423 C CD  . ARG B 2 62  ? 369.961 398.888 502.812 1.00 104.85 ? 62  ARG L CD  1 
ATOM 1424 N NE  . ARG B 2 62  ? 369.472 397.740 503.566 1.00 104.85 ? 62  ARG L NE  1 
ATOM 1425 C CZ  . ARG B 2 62  ? 368.243 397.647 504.065 1.00 104.85 ? 62  ARG L CZ  1 
ATOM 1426 N NH1 . ARG B 2 62  ? 367.375 398.630 503.882 1.00 104.85 ? 62  ARG L NH1 1 
ATOM 1427 N NH2 . ARG B 2 62  ? 367.880 396.572 504.748 1.00 104.85 ? 62  ARG L NH2 1 
ATOM 1428 N N   . PHE B 2 63  ? 370.982 394.965 498.758 1.00 99.32  ? 63  PHE L N   1 
ATOM 1429 C CA  . PHE B 2 63  ? 371.650 393.690 498.547 1.00 99.32  ? 63  PHE L CA  1 
ATOM 1430 C C   . PHE B 2 63  ? 371.893 393.451 497.065 1.00 99.32  ? 63  PHE L C   1 
ATOM 1431 O O   . PHE B 2 63  ? 371.126 393.910 496.216 1.00 99.32  ? 63  PHE L O   1 
ATOM 1432 C CB  . PHE B 2 63  ? 370.804 392.542 499.094 1.00 99.32  ? 63  PHE L CB  1 
ATOM 1433 C CG  . PHE B 2 63  ? 370.352 392.724 500.510 1.00 99.32  ? 63  PHE L CG  1 
ATOM 1434 C CD1 . PHE B 2 63  ? 371.137 392.287 501.558 1.00 99.32  ? 63  PHE L CD1 1 
ATOM 1435 C CD2 . PHE B 2 63  ? 369.121 393.292 500.792 1.00 99.32  ? 63  PHE L CD2 1 
ATOM 1436 C CE1 . PHE B 2 63  ? 370.715 392.433 502.858 1.00 99.32  ? 63  PHE L CE1 1 
ATOM 1437 C CE2 . PHE B 2 63  ? 368.698 393.447 502.087 1.00 99.32  ? 63  PHE L CE2 1 
ATOM 1438 C CZ  . PHE B 2 63  ? 369.494 393.015 503.122 1.00 99.32  ? 63  PHE L CZ  1 
ATOM 1439 N N   . SER B 2 64  ? 372.949 392.703 496.759 1.00 98.75  ? 64  SER L N   1 
ATOM 1440 C CA  . SER B 2 64  ? 373.161 392.214 495.399 1.00 98.75  ? 64  SER L CA  1 
ATOM 1441 C C   . SER B 2 64  ? 374.021 390.968 495.472 1.00 98.75  ? 64  SER L C   1 
ATOM 1442 O O   . SER B 2 64  ? 375.156 391.032 495.950 1.00 98.75  ? 64  SER L O   1 
ATOM 1443 C CB  . SER B 2 64  ? 373.831 393.267 494.520 1.00 98.75  ? 64  SER L CB  1 
ATOM 1444 O OG  . SER B 2 64  ? 375.176 393.474 494.911 1.00 98.75  ? 64  SER L OG  1 
ATOM 1445 N N   . GLY B 2 65  ? 373.499 389.850 494.990 1.00 94.42  ? 65  GLY L N   1 
ATOM 1446 C CA  . GLY B 2 65  ? 374.256 388.624 494.920 1.00 94.42  ? 65  GLY L CA  1 
ATOM 1447 C C   . GLY B 2 65  ? 375.051 388.529 493.633 1.00 94.42  ? 65  GLY L C   1 
ATOM 1448 O O   . GLY B 2 65  ? 374.767 389.211 492.655 1.00 94.42  ? 65  GLY L O   1 
ATOM 1449 N N   . SER B 2 66  ? 376.048 387.655 493.642 1.00 94.91  ? 66  SER L N   1 
ATOM 1450 C CA  . SER B 2 66  ? 376.941 387.493 492.505 1.00 94.91  ? 66  SER L CA  1 
ATOM 1451 C C   . SER B 2 66  ? 377.585 386.117 492.595 1.00 94.91  ? 66  SER L C   1 
ATOM 1452 O O   . SER B 2 66  ? 377.122 385.244 493.333 1.00 94.91  ? 66  SER L O   1 
ATOM 1453 C CB  . SER B 2 66  ? 377.989 388.604 492.477 1.00 94.91  ? 66  SER L CB  1 
ATOM 1454 O OG  . SER B 2 66  ? 378.827 388.518 493.613 1.00 94.91  ? 66  SER L OG  1 
ATOM 1455 N N   . GLY B 2 67  ? 378.656 385.922 491.844 1.00 94.96  ? 67  GLY L N   1 
ATOM 1456 C CA  . GLY B 2 67  ? 379.382 384.674 491.881 1.00 94.96  ? 67  GLY L CA  1 
ATOM 1457 C C   . GLY B 2 67  ? 378.905 383.705 490.815 1.00 94.96  ? 67  GLY L C   1 
ATOM 1458 O O   . GLY B 2 67  ? 377.784 383.784 490.312 1.00 94.96  ? 67  GLY L O   1 
ATOM 1459 N N   . SER B 2 68  ? 379.792 382.787 490.449 1.00 95.45  ? 68  SER L N   1 
ATOM 1460 C CA  . SER B 2 68  ? 379.473 381.733 489.495 1.00 95.45  ? 68  SER L CA  1 
ATOM 1461 C C   . SER B 2 68  ? 380.348 380.527 489.803 1.00 95.45  ? 68  SER L C   1 
ATOM 1462 O O   . SER B 2 68  ? 381.211 380.572 490.683 1.00 95.45  ? 68  SER L O   1 
ATOM 1463 C CB  . SER B 2 68  ? 379.670 382.197 488.049 1.00 95.45  ? 68  SER L CB  1 
ATOM 1464 O OG  . SER B 2 68  ? 378.904 383.350 487.758 1.00 95.45  ? 68  SER L OG  1 
ATOM 1465 N N   . GLY B 2 69  ? 380.118 379.446 489.064 1.00 92.68  ? 69  GLY L N   1 
ATOM 1466 C CA  . GLY B 2 69  ? 380.925 378.248 489.176 1.00 92.68  ? 69  GLY L CA  1 
ATOM 1467 C C   . GLY B 2 69  ? 380.751 377.507 490.482 1.00 92.68  ? 69  GLY L C   1 
ATOM 1468 O O   . GLY B 2 69  ? 379.728 376.862 490.717 1.00 92.68  ? 69  GLY L O   1 
ATOM 1469 N N   . THR B 2 70  ? 381.763 377.585 491.334 1.00 96.77  ? 70  THR L N   1 
ATOM 1470 C CA  . THR B 2 70  ? 381.727 376.982 492.653 1.00 96.77  ? 70  THR L CA  1 
ATOM 1471 C C   . THR B 2 70  ? 381.955 377.983 493.771 1.00 96.77  ? 70  THR L C   1 
ATOM 1472 O O   . THR B 2 70  ? 382.195 377.571 494.909 1.00 96.77  ? 70  THR L O   1 
ATOM 1473 C CB  . THR B 2 70  ? 382.772 375.867 492.752 1.00 96.77  ? 70  THR L CB  1 
ATOM 1474 O OG1 . THR B 2 70  ? 382.689 375.245 494.038 1.00 96.77  ? 70  THR L OG1 1 
ATOM 1475 C CG2 . THR B 2 70  ? 384.168 376.425 492.541 1.00 96.77  ? 70  THR L CG2 1 
ATOM 1476 N N   . SER B 2 71  ? 381.879 379.280 493.489 1.00 96.91  ? 71  SER L N   1 
ATOM 1477 C CA  . SER B 2 71  ? 382.087 380.318 494.488 1.00 96.91  ? 71  SER L CA  1 
ATOM 1478 C C   . SER B 2 71  ? 381.020 381.380 494.314 1.00 96.91  ? 71  SER L C   1 
ATOM 1479 O O   . SER B 2 71  ? 380.945 382.011 493.256 1.00 96.91  ? 71  SER L O   1 
ATOM 1480 C CB  . SER B 2 71  ? 383.469 380.945 494.347 1.00 96.91  ? 71  SER L CB  1 
ATOM 1481 O OG  . SER B 2 71  ? 383.415 382.024 493.431 1.00 96.91  ? 71  SER L OG  1 
ATOM 1482 N N   . TYR B 2 72  ? 380.211 381.588 495.345 1.00 93.72  ? 72  TYR L N   1 
ATOM 1483 C CA  . TYR B 2 72  ? 379.117 382.543 495.301 1.00 93.72  ? 72  TYR L CA  1 
ATOM 1484 C C   . TYR B 2 72  ? 379.206 383.469 496.502 1.00 93.72  ? 72  TYR L C   1 
ATOM 1485 O O   . TYR B 2 72  ? 379.744 383.105 497.549 1.00 93.72  ? 72  TYR L O   1 
ATOM 1486 C CB  . TYR B 2 72  ? 377.766 381.829 495.275 1.00 93.72  ? 72  TYR L CB  1 
ATOM 1487 C CG  . TYR B 2 72  ? 377.487 381.160 493.959 1.00 93.72  ? 72  TYR L CG  1 
ATOM 1488 C CD1 . TYR B 2 72  ? 377.990 379.904 493.676 1.00 93.72  ? 72  TYR L CD1 1 
ATOM 1489 C CD2 . TYR B 2 72  ? 376.740 381.795 492.990 1.00 93.72  ? 72  TYR L CD2 1 
ATOM 1490 C CE1 . TYR B 2 72  ? 377.748 379.304 492.469 1.00 93.72  ? 72  TYR L CE1 1 
ATOM 1491 C CE2 . TYR B 2 72  ? 376.493 381.198 491.782 1.00 93.72  ? 72  TYR L CE2 1 
ATOM 1492 C CZ  . TYR B 2 72  ? 377.000 379.957 491.530 1.00 93.72  ? 72  TYR L CZ  1 
ATOM 1493 O OH  . TYR B 2 72  ? 376.754 379.360 490.326 1.00 93.72  ? 72  TYR L OH  1 
ATOM 1494 N N   . SER B 2 73  ? 378.668 384.675 496.347 1.00 96.22  ? 73  SER L N   1 
ATOM 1495 C CA  . SER B 2 73  ? 378.810 385.679 497.389 1.00 96.22  ? 73  SER L CA  1 
ATOM 1496 C C   . SER B 2 73  ? 377.558 386.535 497.470 1.00 96.22  ? 73  SER L C   1 
ATOM 1497 O O   . SER B 2 73  ? 376.683 386.470 496.605 1.00 96.22  ? 73  SER L O   1 
ATOM 1498 C CB  . SER B 2 73  ? 380.030 386.570 497.150 1.00 96.22  ? 73  SER L CB  1 
ATOM 1499 O OG  . SER B 2 73  ? 379.848 387.372 496.002 1.00 96.22  ? 73  SER L OG  1 
ATOM 1500 N N   . LEU B 2 74  ? 377.489 387.335 498.529 1.00 99.25  ? 74  LEU L N   1 
ATOM 1501 C CA  . LEU B 2 74  ? 376.371 388.227 498.803 1.00 99.25  ? 74  LEU L CA  1 
ATOM 1502 C C   . LEU B 2 74  ? 376.914 389.493 499.445 1.00 99.25  ? 74  LEU L C   1 
ATOM 1503 O O   . LEU B 2 74  ? 377.624 389.418 500.450 1.00 99.25  ? 74  LEU L O   1 
ATOM 1504 C CB  . LEU B 2 74  ? 375.362 387.558 499.726 1.00 99.25  ? 74  LEU L CB  1 
ATOM 1505 C CG  . LEU B 2 74  ? 374.353 388.506 500.343 1.00 99.25  ? 74  LEU L CG  1 
ATOM 1506 C CD1 . LEU B 2 74  ? 373.377 388.931 499.282 1.00 99.25  ? 74  LEU L CD1 1 
ATOM 1507 C CD2 . LEU B 2 74  ? 373.645 387.833 501.487 1.00 99.25  ? 74  LEU L CD2 1 
ATOM 1508 N N   . THR B 2 75  ? 376.581 390.650 498.879 1.00 104.52 ? 75  THR L N   1 
ATOM 1509 C CA  . THR B 2 75  ? 377.114 391.925 499.336 1.00 104.52 ? 75  THR L CA  1 
ATOM 1510 C C   . THR B 2 75  ? 375.999 392.823 499.843 1.00 104.52 ? 75  THR L C   1 
ATOM 1511 O O   . THR B 2 75  ? 374.942 392.929 499.218 1.00 104.52 ? 75  THR L O   1 
ATOM 1512 C CB  . THR B 2 75  ? 377.850 392.655 498.219 1.00 104.52 ? 75  THR L CB  1 
ATOM 1513 O OG1 . THR B 2 75  ? 376.920 392.984 497.182 1.00 104.52 ? 75  THR L OG1 1 
ATOM 1514 C CG2 . THR B 2 75  ? 378.945 391.781 497.644 1.00 104.52 ? 75  THR L CG2 1 
ATOM 1515 N N   . ILE B 2 76  ? 376.251 393.485 500.967 1.00 109.88 ? 76  ILE L N   1 
ATOM 1516 C CA  . ILE B 2 76  ? 375.352 394.492 501.514 1.00 109.88 ? 76  ILE L CA  1 
ATOM 1517 C C   . ILE B 2 76  ? 376.018 395.850 501.364 1.00 109.88 ? 76  ILE L C   1 
ATOM 1518 O O   . ILE B 2 76  ? 377.088 396.086 501.937 1.00 109.88 ? 76  ILE L O   1 
ATOM 1519 C CB  . ILE B 2 76  ? 375.022 394.204 502.984 1.00 109.88 ? 76  ILE L CB  1 
ATOM 1520 C CG1 . ILE B 2 76  ? 374.572 392.753 503.136 1.00 109.88 ? 76  ILE L CG1 1 
ATOM 1521 C CG2 . ILE B 2 76  ? 373.958 395.161 503.467 1.00 109.88 ? 76  ILE L CG2 1 
ATOM 1522 C CD1 . ILE B 2 76  ? 373.986 392.416 504.487 1.00 109.88 ? 76  ILE L CD1 1 
ATOM 1523 N N   . SER B 2 77  ? 375.383 396.747 500.604 1.00 112.17 ? 77  SER L N   1 
ATOM 1524 C CA  . SER B 2 77  ? 376.009 398.023 500.270 1.00 112.17 ? 77  SER L CA  1 
ATOM 1525 C C   . SER B 2 77  ? 376.055 398.953 501.475 1.00 112.17 ? 77  SER L C   1 
ATOM 1526 O O   . SER B 2 77  ? 377.061 399.631 501.710 1.00 112.17 ? 77  SER L O   1 
ATOM 1527 C CB  . SER B 2 77  ? 375.263 398.684 499.113 1.00 112.17 ? 77  SER L CB  1 
ATOM 1528 O OG  . SER B 2 77  ? 375.680 398.153 497.870 1.00 112.17 ? 77  SER L OG  1 
ATOM 1529 N N   . SER B 2 78  ? 374.971 399.009 502.240 1.00 115.72 ? 78  SER L N   1 
ATOM 1530 C CA  . SER B 2 78  ? 374.908 399.805 503.456 1.00 115.72 ? 78  SER L CA  1 
ATOM 1531 C C   . SER B 2 78  ? 374.131 399.025 504.501 1.00 115.72 ? 78  SER L C   1 
ATOM 1532 O O   . SER B 2 78  ? 372.994 398.615 504.253 1.00 115.72 ? 78  SER L O   1 
ATOM 1533 C CB  . SER B 2 78  ? 374.250 401.159 503.197 1.00 115.72 ? 78  SER L CB  1 
ATOM 1534 O OG  . SER B 2 78  ? 374.814 401.781 502.057 1.00 115.72 ? 78  SER L OG  1 
ATOM 1535 N N   . VAL B 2 79  ? 374.743 398.808 505.654 1.00 118.48 ? 79  VAL L N   1 
ATOM 1536 C CA  . VAL B 2 79  ? 374.160 397.972 506.695 1.00 118.48 ? 79  VAL L CA  1 
ATOM 1537 C C   . VAL B 2 79  ? 373.274 398.830 507.584 1.00 118.48 ? 79  VAL L C   1 
ATOM 1538 O O   . VAL B 2 79  ? 373.705 399.877 508.077 1.00 118.48 ? 79  VAL L O   1 
ATOM 1539 C CB  . VAL B 2 79  ? 375.259 397.281 507.514 1.00 118.48 ? 79  VAL L CB  1 
ATOM 1540 C CG1 . VAL B 2 79  ? 374.671 396.554 508.696 1.00 118.48 ? 79  VAL L CG1 1 
ATOM 1541 C CG2 . VAL B 2 79  ? 376.026 396.326 506.642 1.00 118.48 ? 79  VAL L CG2 1 
ATOM 1542 N N   . GLU B 2 80  ? 372.037 398.397 507.781 1.00 117.90 ? 80  GLU L N   1 
ATOM 1543 C CA  . GLU B 2 80  ? 371.102 399.054 508.681 1.00 117.90 ? 80  GLU L CA  1 
ATOM 1544 C C   . GLU B 2 80  ? 371.048 398.270 509.989 1.00 117.90 ? 80  GLU L C   1 
ATOM 1545 O O   . GLU B 2 80  ? 371.848 397.365 510.226 1.00 117.90 ? 80  GLU L O   1 
ATOM 1546 C CB  . GLU B 2 80  ? 369.725 399.184 508.032 1.00 117.90 ? 80  GLU L CB  1 
ATOM 1547 C CG  . GLU B 2 80  ? 369.765 399.636 506.587 1.00 117.90 ? 80  GLU L CG  1 
ATOM 1548 C CD  . GLU B 2 80  ? 370.652 400.842 506.382 1.00 117.90 ? 80  GLU L CD  1 
ATOM 1549 O OE1 . GLU B 2 80  ? 370.355 401.903 506.963 1.00 117.90 ? 80  GLU L OE1 1 
ATOM 1550 O OE2 . GLU B 2 80  ? 371.657 400.728 505.655 1.00 117.90 ? 80  GLU L OE2 1 
ATOM 1551 N N   . ALA B 2 81  ? 370.106 398.633 510.850 1.00 118.38 ? 81  ALA L N   1 
ATOM 1552 C CA  . ALA B 2 81  ? 369.972 397.970 512.137 1.00 118.38 ? 81  ALA L CA  1 
ATOM 1553 C C   . ALA B 2 81  ? 368.962 396.834 512.125 1.00 118.38 ? 81  ALA L C   1 
ATOM 1554 O O   . ALA B 2 81  ? 369.080 395.911 512.937 1.00 118.38 ? 81  ALA L O   1 
ATOM 1555 C CB  . ALA B 2 81  ? 369.577 398.986 513.210 1.00 118.38 ? 81  ALA L CB  1 
ATOM 1556 N N   . GLU B 2 82  ? 367.990 396.871 511.218 1.00 116.28 ? 82  GLU L N   1 
ATOM 1557 C CA  . GLU B 2 82  ? 366.869 395.943 511.213 1.00 116.28 ? 82  GLU L CA  1 
ATOM 1558 C C   . GLU B 2 82  ? 367.128 394.689 510.395 1.00 116.28 ? 82  GLU L C   1 
ATOM 1559 O O   . GLU B 2 82  ? 366.255 393.820 510.334 1.00 116.28 ? 82  GLU L O   1 
ATOM 1560 C CB  . GLU B 2 82  ? 365.619 396.640 510.670 1.00 116.28 ? 82  GLU L CB  1 
ATOM 1561 C CG  . GLU B 2 82  ? 365.706 397.025 509.198 1.00 116.28 ? 82  GLU L CG  1 
ATOM 1562 C CD  . GLU B 2 82  ? 366.389 398.363 508.957 1.00 116.28 ? 82  GLU L CD  1 
ATOM 1563 O OE1 . GLU B 2 82  ? 366.923 398.954 509.920 1.00 116.28 ? 82  GLU L OE1 1 
ATOM 1564 O OE2 . GLU B 2 82  ? 366.385 398.827 507.798 1.00 116.28 ? 82  GLU L OE2 1 
ATOM 1565 N N   . ASP B 2 83  ? 368.286 394.581 509.753 1.00 114.27 ? 83  ASP L N   1 
ATOM 1566 C CA  . ASP B 2 83  ? 368.624 393.422 508.934 1.00 114.27 ? 83  ASP L CA  1 
ATOM 1567 C C   . ASP B 2 83  ? 369.730 392.593 509.560 1.00 114.27 ? 83  ASP L C   1 
ATOM 1568 O O   . ASP B 2 83  ? 370.639 392.135 508.868 1.00 114.27 ? 83  ASP L O   1 
ATOM 1569 C CB  . ASP B 2 83  ? 369.012 393.863 507.530 1.00 114.27 ? 83  ASP L CB  1 
ATOM 1570 C CG  . ASP B 2 83  ? 369.945 395.037 507.536 1.00 114.27 ? 83  ASP L CG  1 
ATOM 1571 O OD1 . ASP B 2 83  ? 370.174 395.591 508.626 1.00 114.27 ? 83  ASP L OD1 1 
ATOM 1572 O OD2 . ASP B 2 83  ? 370.449 395.409 506.458 1.00 114.27 ? 83  ASP L OD2 1 
ATOM 1573 N N   . ALA B 2 84  ? 369.691 392.412 510.873 1.00 110.68 ? 84  ALA L N   1 
ATOM 1574 C CA  . ALA B 2 84  ? 370.620 391.534 511.577 1.00 110.68 ? 84  ALA L CA  1 
ATOM 1575 C C   . ALA B 2 84  ? 369.915 390.203 511.774 1.00 110.68 ? 84  ALA L C   1 
ATOM 1576 O O   . ALA B 2 84  ? 368.979 390.098 512.569 1.00 110.68 ? 84  ALA L O   1 
ATOM 1577 C CB  . ALA B 2 84  ? 371.050 392.141 512.905 1.00 110.68 ? 84  ALA L CB  1 
ATOM 1578 N N   . ALA B 2 85  ? 370.360 389.188 511.046 1.00 105.43 ? 85  ALA L N   1 
ATOM 1579 C CA  . ALA B 2 85  ? 369.747 387.870 511.099 1.00 105.43 ? 85  ALA L CA  1 
ATOM 1580 C C   . ALA B 2 85  ? 370.772 386.847 510.636 1.00 105.43 ? 85  ALA L C   1 
ATOM 1581 O O   . ALA B 2 85  ? 371.972 387.130 510.563 1.00 105.43 ? 85  ALA L O   1 
ATOM 1582 C CB  . ALA B 2 85  ? 368.480 387.811 510.244 1.00 105.43 ? 85  ALA L CB  1 
ATOM 1583 N N   . THR B 2 86  ? 370.294 385.649 510.331 1.00 101.69 ? 86  THR L N   1 
ATOM 1584 C CA  . THR B 2 86  ? 371.116 384.576 509.801 1.00 101.69 ? 86  THR L CA  1 
ATOM 1585 C C   . THR B 2 86  ? 370.792 384.404 508.325 1.00 101.69 ? 86  THR L C   1 
ATOM 1586 O O   . THR B 2 86  ? 369.624 384.466 507.936 1.00 101.69 ? 86  THR L O   1 
ATOM 1587 C CB  . THR B 2 86  ? 370.859 383.278 510.558 1.00 101.69 ? 86  THR L CB  1 
ATOM 1588 O OG1 . THR B 2 86  ? 370.683 383.570 511.947 1.00 101.69 ? 86  THR L OG1 1 
ATOM 1589 C CG2 . THR B 2 86  ? 372.036 382.345 510.403 1.00 101.69 ? 86  THR L CG2 1 
ATOM 1590 N N   . TYR B 2 87  ? 371.818 384.202 507.508 1.00 99.67  ? 87  TYR L N   1 
ATOM 1591 C CA  . TYR B 2 87  ? 371.654 384.084 506.068 1.00 99.67  ? 87  TYR L CA  1 
ATOM 1592 C C   . TYR B 2 87  ? 372.166 382.733 505.600 1.00 99.67  ? 87  TYR L C   1 
ATOM 1593 O O   . TYR B 2 87  ? 373.328 382.392 505.834 1.00 99.67  ? 87  TYR L O   1 
ATOM 1594 C CB  . TYR B 2 87  ? 372.388 385.210 505.345 1.00 99.67  ? 87  TYR L CB  1 
ATOM 1595 C CG  . TYR B 2 87  ? 371.844 386.577 505.676 1.00 99.67  ? 87  TYR L CG  1 
ATOM 1596 C CD1 . TYR B 2 87  ? 370.687 387.044 505.075 1.00 99.67  ? 87  TYR L CD1 1 
ATOM 1597 C CD2 . TYR B 2 87  ? 372.482 387.394 506.592 1.00 99.67  ? 87  TYR L CD2 1 
ATOM 1598 C CE1 . TYR B 2 87  ? 370.185 388.281 505.376 1.00 99.67  ? 87  TYR L CE1 1 
ATOM 1599 C CE2 . TYR B 2 87  ? 371.986 388.637 506.898 1.00 99.67  ? 87  TYR L CE2 1 
ATOM 1600 C CZ  . TYR B 2 87  ? 370.837 389.073 506.288 1.00 99.67  ? 87  TYR L CZ  1 
ATOM 1601 O OH  . TYR B 2 87  ? 370.333 390.314 506.589 1.00 99.67  ? 87  TYR L OH  1 
ATOM 1602 N N   . TYR B 2 88  ? 371.301 381.973 504.933 1.00 95.02  ? 88  TYR L N   1 
ATOM 1603 C CA  . TYR B 2 88  ? 371.630 380.652 504.427 1.00 95.02  ? 88  TYR L CA  1 
ATOM 1604 C C   . TYR B 2 88  ? 371.651 380.658 502.906 1.00 95.02  ? 88  TYR L C   1 
ATOM 1605 O O   . TYR B 2 88  ? 370.959 381.449 502.266 1.00 95.02  ? 88  TYR L O   1 
ATOM 1606 C CB  . TYR B 2 88  ? 370.619 379.615 504.896 1.00 95.02  ? 88  TYR L CB  1 
ATOM 1607 C CG  . TYR B 2 88  ? 370.436 379.518 506.385 1.00 95.02  ? 88  TYR L CG  1 
ATOM 1608 C CD1 . TYR B 2 88  ? 371.313 378.780 507.165 1.00 95.02  ? 88  TYR L CD1 1 
ATOM 1609 C CD2 . TYR B 2 88  ? 369.363 380.133 507.008 1.00 95.02  ? 88  TYR L CD2 1 
ATOM 1610 C CE1 . TYR B 2 88  ? 371.136 378.677 508.523 1.00 95.02  ? 88  TYR L CE1 1 
ATOM 1611 C CE2 . TYR B 2 88  ? 369.178 380.036 508.367 1.00 95.02  ? 88  TYR L CE2 1 
ATOM 1612 C CZ  . TYR B 2 88  ? 370.066 379.308 509.119 1.00 95.02  ? 88  TYR L CZ  1 
ATOM 1613 O OH  . TYR B 2 88  ? 369.880 379.211 510.475 1.00 95.02  ? 88  TYR L OH  1 
ATOM 1614 N N   . CYS B 2 89  ? 372.447 379.764 502.332 1.00 92.47  ? 89  CYS L N   1 
ATOM 1615 C CA  . CYS B 2 89  ? 372.490 379.557 500.895 1.00 92.47  ? 89  CYS L CA  1 
ATOM 1616 C C   . CYS B 2 89  ? 372.032 378.142 500.596 1.00 92.47  ? 89  CYS L C   1 
ATOM 1617 O O   . CYS B 2 89  ? 372.415 377.198 501.289 1.00 92.47  ? 89  CYS L O   1 
ATOM 1618 C CB  . CYS B 2 89  ? 373.892 379.796 500.307 1.00 92.47  ? 89  CYS L CB  1 
ATOM 1619 S SG  . CYS B 2 89  ? 375.283 379.036 501.180 1.00 92.47  ? 89  CYS L SG  1 
ATOM 1620 N N   . GLN B 2 90  ? 371.195 378.006 499.576 1.00 81.90  ? 90  GLN L N   1 
ATOM 1621 C CA  . GLN B 2 90  ? 370.664 376.730 499.135 1.00 81.90  ? 90  GLN L CA  1 
ATOM 1622 C C   . GLN B 2 90  ? 371.197 376.442 497.741 1.00 81.90  ? 90  GLN L C   1 
ATOM 1623 O O   . GLN B 2 90  ? 371.507 377.358 496.981 1.00 81.90  ? 90  GLN L O   1 
ATOM 1624 C CB  . GLN B 2 90  ? 369.138 376.761 499.122 1.00 81.90  ? 90  GLN L CB  1 
ATOM 1625 C CG  . GLN B 2 90  ? 368.460 375.422 499.024 1.00 81.90  ? 90  GLN L CG  1 
ATOM 1626 C CD  . GLN B 2 90  ? 367.173 375.503 498.249 1.00 81.90  ? 90  GLN L CD  1 
ATOM 1627 O OE1 . GLN B 2 90  ? 366.852 376.531 497.670 1.00 81.90  ? 90  GLN L OE1 1 
ATOM 1628 N NE2 . GLN B 2 90  ? 366.426 374.419 498.237 1.00 81.90  ? 90  GLN L NE2 1 
ATOM 1629 N N   . GLN B 2 91  ? 371.316 375.164 497.403 1.00 79.12  ? 91  GLN L N   1 
ATOM 1630 C CA  . GLN B 2 91  ? 371.747 374.774 496.074 1.00 79.12  ? 91  GLN L CA  1 
ATOM 1631 C C   . GLN B 2 91  ? 370.910 373.605 495.585 1.00 79.12  ? 91  GLN L C   1 
ATOM 1632 O O   . GLN B 2 91  ? 370.085 373.053 496.309 1.00 79.12  ? 91  GLN L O   1 
ATOM 1633 C CB  . GLN B 2 91  ? 373.229 374.408 496.052 1.00 79.12  ? 91  GLN L CB  1 
ATOM 1634 C CG  . GLN B 2 91  ? 373.594 373.324 497.021 1.00 79.12  ? 91  GLN L CG  1 
ATOM 1635 C CD  . GLN B 2 91  ? 373.659 371.970 496.374 1.00 79.12  ? 91  GLN L CD  1 
ATOM 1636 O OE1 . GLN B 2 91  ? 374.400 371.762 495.420 1.00 79.12  ? 91  GLN L OE1 1 
ATOM 1637 N NE2 . GLN B 2 91  ? 372.869 371.038 496.881 1.00 79.12  ? 91  GLN L NE2 1 
ATOM 1638 N N   . PHE B 2 92  ? 371.132 373.239 494.328 1.00 73.35  ? 92  PHE L N   1 
ATOM 1639 C CA  . PHE B 2 92  ? 370.612 371.991 493.783 1.00 73.35  ? 92  PHE L CA  1 
ATOM 1640 C C   . PHE B 2 92  ? 371.541 371.561 492.659 1.00 73.35  ? 92  PHE L C   1 
ATOM 1641 O O   . PHE B 2 92  ? 371.557 372.186 491.598 1.00 73.35  ? 92  PHE L O   1 
ATOM 1642 C CB  . PHE B 2 92  ? 369.191 372.145 493.275 1.00 73.35  ? 92  PHE L CB  1 
ATOM 1643 C CG  . PHE B 2 92  ? 368.759 371.024 492.382 1.00 73.35  ? 92  PHE L CG  1 
ATOM 1644 C CD1 . PHE B 2 92  ? 368.569 369.759 492.889 1.00 73.35  ? 92  PHE L CD1 1 
ATOM 1645 C CD2 . PHE B 2 92  ? 368.563 371.228 491.033 1.00 73.35  ? 92  PHE L CD2 1 
ATOM 1646 C CE1 . PHE B 2 92  ? 368.186 368.730 492.073 1.00 73.35  ? 92  PHE L CE1 1 
ATOM 1647 C CE2 . PHE B 2 92  ? 368.185 370.193 490.215 1.00 73.35  ? 92  PHE L CE2 1 
ATOM 1648 C CZ  . PHE B 2 92  ? 367.994 368.949 490.738 1.00 73.35  ? 92  PHE L CZ  1 
ATOM 1649 N N   . SER B 2 93  ? 372.321 370.522 492.899 0.00 75.81  ? 93  SER L N   1 
ATOM 1650 C CA  . SER B 2 93  ? 373.038 369.828 491.843 0.00 75.81  ? 93  SER L CA  1 
ATOM 1651 C C   . SER B 2 93  ? 372.407 368.492 491.512 0.00 75.81  ? 93  SER L C   1 
ATOM 1652 O O   . SER B 2 93  ? 372.211 368.171 490.341 0.00 75.81  ? 93  SER L O   1 
ATOM 1653 C CB  . SER B 2 93  ? 374.490 369.621 492.256 0.00 75.81  ? 93  SER L CB  1 
ATOM 1654 O OG  . SER B 2 93  ? 374.556 369.214 493.607 0.00 75.81  ? 93  SER L OG  1 
ATOM 1655 N N   . GLY B 2 94  ? 372.102 367.708 492.535 1.00 74.27  ? 94  GLY L N   1 
ATOM 1656 C CA  . GLY B 2 94  ? 371.159 366.616 492.442 1.00 74.27  ? 94  GLY L CA  1 
ATOM 1657 C C   . GLY B 2 94  ? 370.363 366.658 493.724 1.00 74.27  ? 94  GLY L C   1 
ATOM 1658 O O   . GLY B 2 94  ? 370.475 367.600 494.507 1.00 74.27  ? 94  GLY L O   1 
ATOM 1659 N N   . TYR B 2 95  ? 369.554 365.643 493.940 1.00 72.44  ? 95  TYR L N   1 
ATOM 1660 C CA  . TYR B 2 95  ? 368.857 365.572 495.208 1.00 72.44  ? 95  TYR L CA  1 
ATOM 1661 C C   . TYR B 2 95  ? 369.811 365.046 496.275 1.00 72.44  ? 95  TYR L C   1 
ATOM 1662 O O   . TYR B 2 95  ? 370.653 364.193 495.985 1.00 72.44  ? 95  TYR L O   1 
ATOM 1663 C CB  . TYR B 2 95  ? 367.630 364.682 495.094 1.00 72.44  ? 95  TYR L CB  1 
ATOM 1664 C CG  . TYR B 2 95  ? 366.599 365.255 494.174 1.00 72.44  ? 95  TYR L CG  1 
ATOM 1665 C CD1 . TYR B 2 95  ? 365.700 366.201 494.618 1.00 72.44  ? 95  TYR L CD1 1 
ATOM 1666 C CD2 . TYR B 2 95  ? 366.542 364.867 492.854 1.00 72.44  ? 95  TYR L CD2 1 
ATOM 1667 C CE1 . TYR B 2 95  ? 364.767 366.730 493.775 1.00 72.44  ? 95  TYR L CE1 1 
ATOM 1668 C CE2 . TYR B 2 95  ? 365.615 365.387 492.008 1.00 72.44  ? 95  TYR L CE2 1 
ATOM 1669 C CZ  . TYR B 2 95  ? 364.730 366.317 492.469 1.00 72.44  ? 95  TYR L CZ  1 
ATOM 1670 O OH  . TYR B 2 95  ? 363.801 366.832 491.607 1.00 72.44  ? 95  TYR L OH  1 
ATOM 1671 N N   . PRO B 2 96  ? 369.719 365.539 497.516 1.00 74.24  ? 96  PRO L N   1 
ATOM 1672 C CA  . PRO B 2 96  ? 368.763 366.486 498.085 1.00 74.24  ? 96  PRO L CA  1 
ATOM 1673 C C   . PRO B 2 96  ? 369.148 367.942 497.904 1.00 74.24  ? 96  PRO L C   1 
ATOM 1674 O O   . PRO B 2 96  ? 370.185 368.238 497.327 1.00 74.24  ? 96  PRO L O   1 
ATOM 1675 C CB  . PRO B 2 96  ? 368.785 366.124 499.555 1.00 74.24  ? 96  PRO L CB  1 
ATOM 1676 C CG  . PRO B 2 96  ? 370.184 365.732 499.780 1.00 74.24  ? 96  PRO L CG  1 
ATOM 1677 C CD  . PRO B 2 96  ? 370.663 365.063 498.537 1.00 74.24  ? 96  PRO L CD  1 
ATOM 1678 N N   . LEU B 2 97  ? 368.304 368.842 498.397 1.00 77.38  ? 97  LEU L N   1 
ATOM 1679 C CA  . LEU B 2 97  ? 368.596 370.268 498.401 1.00 77.38  ? 97  LEU L CA  1 
ATOM 1680 C C   . LEU B 2 97  ? 369.310 370.595 499.701 1.00 77.38  ? 97  LEU L C   1 
ATOM 1681 O O   . LEU B 2 97  ? 368.695 370.588 500.769 1.00 77.38  ? 97  LEU L O   1 
ATOM 1682 C CB  . LEU B 2 97  ? 367.322 371.090 498.273 1.00 77.38  ? 97  LEU L CB  1 
ATOM 1683 C CG  . LEU B 2 97  ? 366.227 370.568 497.364 1.00 77.38  ? 97  LEU L CG  1 
ATOM 1684 C CD1 . LEU B 2 97  ? 364.998 371.413 497.547 1.00 77.38  ? 97  LEU L CD1 1 
ATOM 1685 C CD2 . LEU B 2 97  ? 366.678 370.596 495.933 1.00 77.38  ? 97  LEU L CD2 1 
ATOM 1686 N N   . THR B 2 98  ? 370.597 370.884 499.617 1.00 82.35  ? 98  THR L N   1 
ATOM 1687 C CA  . THR B 2 98  ? 371.404 371.127 500.798 1.00 82.35  ? 98  THR L CA  1 
ATOM 1688 C C   . THR B 2 98  ? 371.452 372.614 501.093 1.00 82.35  ? 98  THR L C   1 
ATOM 1689 O O   . THR B 2 98  ? 371.483 373.436 500.176 1.00 82.35  ? 98  THR L O   1 
ATOM 1690 C CB  . THR B 2 98  ? 372.817 370.584 500.612 1.00 82.35  ? 98  THR L CB  1 
ATOM 1691 O OG1 . THR B 2 98  ? 373.261 370.882 499.288 1.00 82.35  ? 98  THR L OG1 1 
ATOM 1692 C CG2 . THR B 2 98  ? 372.839 369.081 500.809 1.00 82.35  ? 98  THR L CG2 1 
ATOM 1693 N N   . PHE B 2 99  ? 371.439 372.951 502.375 1.00 87.97  ? 99  PHE L N   1 
ATOM 1694 C CA  . PHE B 2 99  ? 371.540 374.331 502.816 1.00 87.97  ? 99  PHE L CA  1 
ATOM 1695 C C   . PHE B 2 99  ? 372.952 374.626 503.294 1.00 87.97  ? 99  PHE L C   1 
ATOM 1696 O O   . PHE B 2 99  ? 373.812 373.746 503.353 1.00 87.97  ? 99  PHE L O   1 
ATOM 1697 C CB  . PHE B 2 99  ? 370.545 374.623 503.932 1.00 87.97  ? 99  PHE L CB  1 
ATOM 1698 C CG  . PHE B 2 99  ? 369.132 374.710 503.469 1.00 87.97  ? 99  PHE L CG  1 
ATOM 1699 C CD1 . PHE B 2 99  ? 368.362 373.570 503.341 1.00 87.97  ? 99  PHE L CD1 1 
ATOM 1700 C CD2 . PHE B 2 99  ? 368.571 375.930 503.161 1.00 87.97  ? 99  PHE L CD2 1 
ATOM 1701 C CE1 . PHE B 2 99  ? 367.059 373.647 502.914 1.00 87.97  ? 99  PHE L CE1 1 
ATOM 1702 C CE2 . PHE B 2 99  ? 367.268 376.013 502.735 1.00 87.97  ? 99  PHE L CE2 1 
ATOM 1703 C CZ  . PHE B 2 99  ? 366.511 374.869 502.610 1.00 87.97  ? 99  PHE L CZ  1 
ATOM 1704 N N   . GLY B 2 100 ? 373.187 375.885 503.632 1.00 96.08  ? 100 GLY L N   1 
ATOM 1705 C CA  . GLY B 2 100 ? 374.468 376.288 504.159 1.00 96.08  ? 100 GLY L CA  1 
ATOM 1706 C C   . GLY B 2 100 ? 374.602 375.971 505.631 1.00 96.08  ? 100 GLY L C   1 
ATOM 1707 O O   . GLY B 2 100 ? 373.775 375.296 506.241 1.00 96.08  ? 100 GLY L O   1 
ATOM 1708 N N   . ALA B 2 101 ? 375.690 376.472 506.213 1.00 103.48 ? 101 ALA L N   1 
ATOM 1709 C CA  . ALA B 2 101 ? 375.889 376.323 507.648 1.00 103.48 ? 101 ALA L CA  1 
ATOM 1710 C C   . ALA B 2 101 ? 375.232 377.466 508.405 1.00 103.48 ? 101 ALA L C   1 
ATOM 1711 O O   . ALA B 2 101 ? 374.744 377.283 509.526 1.00 103.48 ? 101 ALA L O   1 
ATOM 1712 N N   . GLY B 2 102 ? 375.216 378.656 507.812 1.00 104.70 ? 102 GLY L N   1 
ATOM 1713 C CA  . GLY B 2 102 ? 374.639 379.815 508.461 1.00 104.70 ? 102 GLY L CA  1 
ATOM 1714 C C   . GLY B 2 102 ? 375.664 380.893 508.741 1.00 104.70 ? 102 GLY L C   1 
ATOM 1715 O O   . GLY B 2 102 ? 376.750 380.607 509.252 1.00 104.70 ? 102 GLY L O   1 
ATOM 1716 N N   . THR B 2 103 ? 375.341 382.135 508.399 1.00 107.58 ? 103 THR L N   1 
ATOM 1717 C CA  . THR B 2 103 ? 376.206 383.278 508.658 1.00 107.58 ? 103 THR L CA  1 
ATOM 1718 C C   . THR B 2 103 ? 375.427 384.291 509.477 1.00 107.58 ? 103 THR L C   1 
ATOM 1719 O O   . THR B 2 103 ? 374.426 384.836 509.004 1.00 107.58 ? 103 THR L O   1 
ATOM 1720 C CB  . THR B 2 103 ? 376.700 383.909 507.358 1.00 107.58 ? 103 THR L CB  1 
ATOM 1721 O OG1 . THR B 2 103 ? 377.580 383.003 506.685 1.00 107.58 ? 103 THR L OG1 1 
ATOM 1722 C CG2 . THR B 2 103 ? 377.436 385.197 507.644 1.00 107.58 ? 103 THR L CG2 1 
ATOM 1723 N N   . LYS B 2 104 ? 375.878 384.535 510.699 1.00 110.46 ? 104 LYS L N   1 
ATOM 1724 C CA  . LYS B 2 104 ? 375.175 385.403 511.629 1.00 110.46 ? 104 LYS L CA  1 
ATOM 1725 C C   . LYS B 2 104 ? 375.775 386.801 511.581 1.00 110.46 ? 104 LYS L C   1 
ATOM 1726 O O   . LYS B 2 104 ? 376.989 386.968 511.724 1.00 110.46 ? 104 LYS L O   1 
ATOM 1727 C CB  . LYS B 2 104 ? 375.238 384.834 513.046 1.00 110.46 ? 104 LYS L CB  1 
ATOM 1728 C CG  . LYS B 2 104 ? 374.606 385.713 514.102 1.00 110.46 ? 104 LYS L CG  1 
ATOM 1729 C CD  . LYS B 2 104 ? 373.160 386.030 513.787 1.00 110.46 ? 104 LYS L CD  1 
ATOM 1730 C CE  . LYS B 2 104 ? 372.511 386.774 514.934 1.00 110.46 ? 104 LYS L CE  1 
ATOM 1731 N NZ  . LYS B 2 104 ? 372.981 386.263 516.248 1.00 110.46 ? 104 LYS L NZ  1 
ATOM 1732 N N   . LEU B 2 105 ? 374.919 387.798 511.381 1.00 114.61 ? 105 LEU L N   1 
ATOM 1733 C CA  . LEU B 2 105 ? 375.321 389.196 511.299 1.00 114.61 ? 105 LEU L CA  1 
ATOM 1734 C C   . LEU B 2 105 ? 374.816 389.915 512.540 1.00 114.61 ? 105 LEU L C   1 
ATOM 1735 O O   . LEU B 2 105 ? 373.604 390.028 512.750 1.00 114.61 ? 105 LEU L O   1 
ATOM 1736 C CB  . LEU B 2 105 ? 374.774 389.849 510.035 1.00 114.61 ? 105 LEU L CB  1 
ATOM 1737 C CG  . LEU B 2 105 ? 374.848 391.373 510.002 1.00 114.61 ? 105 LEU L CG  1 
ATOM 1738 C CD1 . LEU B 2 105 ? 376.279 391.823 509.838 1.00 114.61 ? 105 LEU L CD1 1 
ATOM 1739 C CD2 . LEU B 2 105 ? 373.984 391.941 508.900 1.00 114.61 ? 105 LEU L CD2 1 
ATOM 1740 N N   . GLU B 2 106 ? 375.742 390.383 513.368 1.00 123.30 ? 106 GLU L N   1 
ATOM 1741 C CA  . GLU B 2 106 ? 375.425 391.216 514.518 1.00 123.30 ? 106 GLU L CA  1 
ATOM 1742 C C   . GLU B 2 106 ? 375.977 392.612 514.276 1.00 123.30 ? 106 GLU L C   1 
ATOM 1743 O O   . GLU B 2 106 ? 377.129 392.766 513.863 1.00 123.30 ? 106 GLU L O   1 
ATOM 1744 C CB  . GLU B 2 106 ? 376.004 390.623 515.805 1.00 123.30 ? 106 GLU L CB  1 
ATOM 1745 C CG  . GLU B 2 106 ? 375.792 391.476 517.061 1.00 123.30 ? 106 GLU L CG  1 
ATOM 1746 C CD  . GLU B 2 106 ? 374.343 391.565 517.503 1.00 123.30 ? 106 GLU L CD  1 
ATOM 1747 O OE1 . GLU B 2 106 ? 373.585 390.605 517.267 1.00 123.30 ? 106 GLU L OE1 1 
ATOM 1748 O OE2 . GLU B 2 106 ? 373.957 392.602 518.080 1.00 123.30 ? 106 GLU L OE2 1 
ATOM 1749 N N   . LEU B 2 107 ? 375.149 393.621 514.512 1.00 125.26 ? 107 LEU L N   1 
ATOM 1750 C CA  . LEU B 2 107 ? 375.578 395.000 514.351 1.00 125.26 ? 107 LEU L CA  1 
ATOM 1751 C C   . LEU B 2 107 ? 376.498 395.406 515.498 1.00 125.26 ? 107 LEU L C   1 
ATOM 1752 O O   . LEU B 2 107 ? 376.458 394.840 516.593 1.00 125.26 ? 107 LEU L O   1 
ATOM 1753 C CB  . LEU B 2 107 ? 374.374 395.942 514.291 1.00 125.26 ? 107 LEU L CB  1 
ATOM 1754 C CG  . LEU B 2 107 ? 373.631 396.372 515.565 1.00 125.26 ? 107 LEU L CG  1 
ATOM 1755 C CD1 . LEU B 2 107 ? 372.648 397.467 515.208 1.00 125.26 ? 107 LEU L CD1 1 
ATOM 1756 C CD2 . LEU B 2 107 ? 372.899 395.246 516.293 1.00 125.26 ? 107 LEU L CD2 1 
ATOM 1757 N N   . LYS B 2 108 ? 377.333 396.405 515.238 1.00 124.32 ? 108 LYS L N   1 
ATOM 1758 C CA  . LYS B 2 108 ? 378.328 396.836 516.213 1.00 124.32 ? 108 LYS L CA  1 
ATOM 1759 C C   . LYS B 2 108 ? 377.964 398.180 516.836 1.00 124.32 ? 108 LYS L C   1 
ATOM 1760 O O   . LYS B 2 108 ? 378.146 399.232 516.224 1.00 124.32 ? 108 LYS L O   1 
ATOM 1761 C CB  . LYS B 2 108 ? 379.707 396.913 515.558 1.00 124.32 ? 108 LYS L CB  1 
ATOM 1762 C CG  . LYS B 2 108 ? 380.835 397.298 516.493 1.00 124.32 ? 108 LYS L CG  1 
ATOM 1763 C CD  . LYS B 2 108 ? 382.174 397.253 515.779 1.00 124.32 ? 108 LYS L CD  1 
ATOM 1764 C CE  . LYS B 2 108 ? 382.544 395.830 515.407 1.00 124.32 ? 108 LYS L CE  1 
ATOM 1765 N NZ  . LYS B 2 108 ? 383.822 395.757 514.647 1.00 124.32 ? 108 LYS L NZ  1 
ATOM 1766 N N   . SER C 3 58  ? 380.928 366.960 446.764 1.00 81.30  ? 58  SER A N   1 
ATOM 1767 C CA  . SER C 3 58  ? 381.534 365.839 447.471 1.00 81.30  ? 58  SER A CA  1 
ATOM 1768 C C   . SER C 3 58  ? 380.548 365.170 448.420 1.00 81.30  ? 58  SER A C   1 
ATOM 1769 O O   . SER C 3 58  ? 380.485 365.513 449.596 1.00 81.30  ? 58  SER A O   1 
ATOM 1770 C CB  . SER C 3 58  ? 382.759 366.301 448.251 1.00 81.30  ? 58  SER A CB  1 
ATOM 1771 O OG  . SER C 3 58  ? 383.051 365.391 449.295 1.00 81.30  ? 58  SER A OG  1 
ATOM 1772 N N   . ARG C 3 59  ? 379.789 364.198 447.911 1.00 82.92  ? 59  ARG A N   1 
ATOM 1773 C CA  . ARG C 3 59  ? 378.722 363.567 448.678 1.00 82.92  ? 59  ARG A CA  1 
ATOM 1774 C C   . ARG C 3 59  ? 378.987 362.073 448.883 1.00 82.92  ? 59  ARG A C   1 
ATOM 1775 O O   . ARG C 3 59  ? 378.174 361.369 449.487 1.00 82.92  ? 59  ARG A O   1 
ATOM 1776 C CB  . ARG C 3 59  ? 377.387 363.819 447.969 1.00 82.92  ? 59  ARG A CB  1 
ATOM 1777 C CG  . ARG C 3 59  ? 376.118 363.714 448.817 1.00 82.92  ? 59  ARG A CG  1 
ATOM 1778 C CD  . ARG C 3 59  ? 374.904 363.950 447.952 1.00 82.92  ? 59  ARG A CD  1 
ATOM 1779 N NE  . ARG C 3 59  ? 374.769 362.871 446.982 1.00 82.92  ? 59  ARG A NE  1 
ATOM 1780 C CZ  . ARG C 3 59  ? 373.970 362.905 445.924 1.00 82.92  ? 59  ARG A CZ  1 
ATOM 1781 N NH1 . ARG C 3 59  ? 373.229 363.977 445.679 1.00 82.92  ? 59  ARG A NH1 1 
ATOM 1782 N NH2 . ARG C 3 59  ? 373.925 361.866 445.103 1.00 82.92  ? 59  ARG A NH2 1 
ATOM 1783 N N   . SER C 3 60  ? 380.134 361.577 448.424 1.00 74.58  ? 60  SER A N   1 
ATOM 1784 C CA  . SER C 3 60  ? 380.494 360.188 448.641 1.00 74.58  ? 60  SER A CA  1 
ATOM 1785 C C   . SER C 3 60  ? 381.228 359.974 449.948 1.00 74.58  ? 60  SER A C   1 
ATOM 1786 O O   . SER C 3 60  ? 381.431 358.824 450.338 1.00 74.58  ? 60  SER A O   1 
ATOM 1787 C CB  . SER C 3 60  ? 381.358 359.661 447.489 1.00 74.58  ? 60  SER A CB  1 
ATOM 1788 O OG  . SER C 3 60  ? 381.428 358.244 447.511 1.00 74.58  ? 60  SER A OG  1 
ATOM 1789 N N   . GLU C 3 61  ? 381.639 361.036 450.626 1.00 70.07  ? 61  GLU A N   1 
ATOM 1790 C CA  . GLU C 3 61  ? 382.212 360.894 451.953 1.00 70.07  ? 61  GLU A CA  1 
ATOM 1791 C C   . GLU C 3 61  ? 381.143 360.784 453.024 1.00 70.07  ? 61  GLU A C   1 
ATOM 1792 O O   . GLU C 3 61  ? 381.428 360.321 454.130 1.00 70.07  ? 61  GLU A O   1 
ATOM 1793 C CB  . GLU C 3 61  ? 383.144 362.074 452.242 1.00 70.07  ? 61  GLU A CB  1 
ATOM 1794 C CG  . GLU C 3 61  ? 384.128 361.843 453.383 1.00 70.07  ? 61  GLU A CG  1 
ATOM 1795 C CD  . GLU C 3 61  ? 385.501 362.403 453.114 1.00 70.07  ? 61  GLU A CD  1 
ATOM 1796 O OE1 . GLU C 3 61  ? 386.444 362.002 453.826 1.00 70.07  ? 61  GLU A OE1 1 
ATOM 1797 O OE2 . GLU C 3 61  ? 385.640 363.233 452.192 1.00 70.07  ? 61  GLU A OE2 1 
ATOM 1798 N N   . SER C 3 62  ? 379.914 361.167 452.716 1.00 64.39  ? 62  SER A N   1 
ATOM 1799 C CA  . SER C 3 62  ? 378.829 361.121 453.678 1.00 64.39  ? 62  SER A CA  1 
ATOM 1800 C C   . SER C 3 62  ? 377.945 359.899 453.521 1.00 64.39  ? 62  SER A C   1 
ATOM 1801 O O   . SER C 3 62  ? 376.871 359.860 454.118 1.00 64.39  ? 62  SER A O   1 
ATOM 1802 C CB  . SER C 3 62  ? 377.974 362.374 453.564 1.00 64.39  ? 62  SER A CB  1 
ATOM 1803 O OG  . SER C 3 62  ? 377.037 362.220 452.523 1.00 64.39  ? 62  SER A OG  1 
ATOM 1804 N N   . SER C 3 63  ? 378.357 358.909 452.739 1.00 60.95  ? 63  SER A N   1 
ATOM 1805 C CA  . SER C 3 63  ? 377.571 357.698 452.597 1.00 60.95  ? 63  SER A CA  1 
ATOM 1806 C C   . SER C 3 63  ? 377.659 356.859 453.862 1.00 60.95  ? 63  SER A C   1 
ATOM 1807 O O   . SER C 3 63  ? 378.432 357.148 454.770 1.00 60.95  ? 63  SER A O   1 
ATOM 1808 C CB  . SER C 3 63  ? 378.050 356.898 451.399 1.00 60.95  ? 63  SER A CB  1 
ATOM 1809 O OG  . SER C 3 63  ? 379.265 356.259 451.701 1.00 60.95  ? 63  SER A OG  1 
ATOM 1810 N N   . ILE C 3 64  ? 376.841 355.808 453.925 1.00 58.30  ? 64  ILE A N   1 
ATOM 1811 C CA  . ILE C 3 64  ? 376.816 354.990 455.134 1.00 58.30  ? 64  ILE A CA  1 
ATOM 1812 C C   . ILE C 3 64  ? 378.068 354.133 455.232 1.00 58.30  ? 64  ILE A C   1 
ATOM 1813 O O   . ILE C 3 64  ? 378.620 353.956 456.323 1.00 58.30  ? 64  ILE A O   1 
ATOM 1814 C CB  . ILE C 3 64  ? 375.527 354.149 455.177 1.00 58.30  ? 64  ILE A CB  1 
ATOM 1815 C CG1 . ILE C 3 64  ? 374.322 355.069 455.272 1.00 58.30  ? 64  ILE A CG1 1 
ATOM 1816 C CG2 . ILE C 3 64  ? 375.490 353.237 456.377 1.00 58.30  ? 64  ILE A CG2 1 
ATOM 1817 C CD1 . ILE C 3 64  ? 374.339 355.938 456.491 1.00 58.30  ? 64  ILE A CD1 1 
ATOM 1818 N N   . GLU C 3 65  ? 378.564 353.632 454.104 1.00 59.43  ? 65  GLU A N   1 
ATOM 1819 C CA  . GLU C 3 65  ? 379.781 352.835 454.129 1.00 59.43  ? 65  GLU A CA  1 
ATOM 1820 C C   . GLU C 3 65  ? 381.003 353.673 454.472 1.00 59.43  ? 65  GLU A C   1 
ATOM 1821 O O   . GLU C 3 65  ? 381.847 353.231 455.249 1.00 59.43  ? 65  GLU A O   1 
ATOM 1822 C CB  . GLU C 3 65  ? 379.971 352.141 452.789 1.00 59.43  ? 65  GLU A CB  1 
ATOM 1823 C CG  . GLU C 3 65  ? 381.185 351.239 452.704 1.00 59.43  ? 65  GLU A CG  1 
ATOM 1824 C CD  . GLU C 3 65  ? 380.933 349.845 453.237 1.00 59.43  ? 65  GLU A CD  1 
ATOM 1825 O OE1 . GLU C 3 65  ? 381.914 349.137 453.549 1.00 59.43  ? 65  GLU A OE1 1 
ATOM 1826 O OE2 . GLU C 3 65  ? 379.758 349.455 453.341 1.00 59.43  ? 65  GLU A OE2 1 
ATOM 1827 N N   . ASN C 3 66  ? 381.104 354.892 453.962 1.00 61.22  ? 66  ASN A N   1 
ATOM 1828 C CA  . ASN C 3 66  ? 382.248 355.736 454.269 1.00 61.22  ? 66  ASN A CA  1 
ATOM 1829 C C   . ASN C 3 66  ? 382.198 356.315 455.667 1.00 61.22  ? 66  ASN A C   1 
ATOM 1830 O O   . ASN C 3 66  ? 383.217 356.791 456.160 1.00 61.22  ? 66  ASN A O   1 
ATOM 1831 C CB  . ASN C 3 66  ? 382.356 356.868 453.262 1.00 61.22  ? 66  ASN A CB  1 
ATOM 1832 C CG  . ASN C 3 66  ? 382.611 356.375 451.881 1.00 61.22  ? 66  ASN A CG  1 
ATOM 1833 O OD1 . ASN C 3 66  ? 383.716 355.966 451.554 1.00 61.22  ? 66  ASN A OD1 1 
ATOM 1834 N ND2 . ASN C 3 66  ? 381.590 356.410 451.048 1.00 61.22  ? 66  ASN A ND2 1 
ATOM 1835 N N   . PHE C 3 67  ? 381.044 356.282 456.314 1.00 54.13  ? 67  PHE A N   1 
ATOM 1836 C CA  . PHE C 3 67  ? 380.890 356.774 457.672 1.00 54.13  ? 67  PHE A CA  1 
ATOM 1837 C C   . PHE C 3 67  ? 381.233 355.724 458.712 1.00 54.13  ? 67  PHE A C   1 
ATOM 1838 O O   . PHE C 3 67  ? 381.765 356.063 459.770 1.00 54.13  ? 67  PHE A O   1 
ATOM 1839 C CB  . PHE C 3 67  ? 379.448 357.252 457.870 1.00 54.13  ? 67  PHE A CB  1 
ATOM 1840 C CG  . PHE C 3 67  ? 379.179 357.890 459.192 1.00 54.13  ? 67  PHE A CG  1 
ATOM 1841 C CD1 . PHE C 3 67  ? 379.839 359.032 459.572 1.00 54.13  ? 67  PHE A CD1 1 
ATOM 1842 C CD2 . PHE C 3 67  ? 378.226 357.367 460.039 1.00 54.13  ? 67  PHE A CD2 1 
ATOM 1843 C CE1 . PHE C 3 67  ? 379.577 359.620 460.783 1.00 54.13  ? 67  PHE A CE1 1 
ATOM 1844 C CE2 . PHE C 3 67  ? 377.966 357.955 461.248 1.00 54.13  ? 67  PHE A CE2 1 
ATOM 1845 C CZ  . PHE C 3 67  ? 378.641 359.080 461.616 1.00 54.13  ? 67  PHE A CZ  1 
ATOM 1846 N N   . LEU C 3 68  ? 380.978 354.452 458.413 1.00 55.36  ? 68  LEU A N   1 
ATOM 1847 C CA  . LEU C 3 68  ? 381.043 353.394 459.404 1.00 55.36  ? 68  LEU A CA  1 
ATOM 1848 C C   . LEU C 3 68  ? 382.088 352.328 459.130 1.00 55.36  ? 68  LEU A C   1 
ATOM 1849 O O   . LEU C 3 68  ? 382.565 351.712 460.084 1.00 55.36  ? 68  LEU A O   1 
ATOM 1850 C CB  . LEU C 3 68  ? 379.677 352.717 459.531 1.00 55.36  ? 68  LEU A CB  1 
ATOM 1851 C CG  . LEU C 3 68  ? 378.633 353.543 460.263 1.00 55.36  ? 68  LEU A CG  1 
ATOM 1852 C CD1 . LEU C 3 68  ? 377.277 352.963 460.051 1.00 55.36  ? 68  LEU A CD1 1 
ATOM 1853 C CD2 . LEU C 3 68  ? 378.963 353.542 461.713 1.00 55.36  ? 68  LEU A CD2 1 
ATOM 1854 N N   . CYS C 3 69  ? 382.463 352.082 457.874 1.00 57.03  ? 69  CYS A N   1 
ATOM 1855 C CA  . CYS C 3 69  ? 383.504 351.094 457.579 1.00 57.03  ? 69  CYS A CA  1 
ATOM 1856 C C   . CYS C 3 69  ? 384.858 351.756 457.814 1.00 57.03  ? 69  CYS A C   1 
ATOM 1857 O O   . CYS C 3 69  ? 385.548 352.197 456.895 1.00 57.03  ? 69  CYS A O   1 
ATOM 1858 C CB  . CYS C 3 69  ? 383.357 350.556 456.161 1.00 57.03  ? 69  CYS A CB  1 
ATOM 1859 S SG  . CYS C 3 69  ? 384.645 349.462 455.514 1.00 57.03  ? 69  CYS A SG  1 
ATOM 1860 N N   . ARG C 3 70  ? 385.212 351.877 459.092 1.00 54.15  ? 70  ARG A N   1 
ATOM 1861 C CA  . ARG C 3 70  ? 386.493 352.394 459.546 1.00 54.15  ? 70  ARG A CA  1 
ATOM 1862 C C   . ARG C 3 70  ? 386.982 351.513 460.680 1.00 54.15  ? 70  ARG A C   1 
ATOM 1863 O O   . ARG C 3 70  ? 386.191 350.984 461.460 1.00 54.15  ? 70  ARG A O   1 
ATOM 1864 C CB  . ARG C 3 70  ? 386.400 353.843 460.040 1.00 54.15  ? 70  ARG A CB  1 
ATOM 1865 C CG  . ARG C 3 70  ? 385.728 354.815 459.116 1.00 54.15  ? 70  ARG A CG  1 
ATOM 1866 C CD  . ARG C 3 70  ? 386.726 355.642 458.377 1.00 54.15  ? 70  ARG A CD  1 
ATOM 1867 N NE  . ARG C 3 70  ? 386.070 356.489 457.396 1.00 54.15  ? 70  ARG A NE  1 
ATOM 1868 C CZ  . ARG C 3 70  ? 386.595 357.601 456.910 1.00 54.15  ? 70  ARG A CZ  1 
ATOM 1869 N NH1 . ARG C 3 70  ? 387.784 357.998 457.320 1.00 54.15  ? 70  ARG A NH1 1 
ATOM 1870 N NH2 . ARG C 3 70  ? 385.929 358.318 456.021 1.00 54.15  ? 70  ARG A NH2 1 
ATOM 1871 N N   . SER C 3 71  ? 388.296 351.373 460.793 1.00 52.66  ? 71  SER A N   1 
ATOM 1872 C CA  . SER C 3 71  ? 388.906 350.481 461.765 1.00 52.66  ? 71  SER A CA  1 
ATOM 1873 C C   . SER C 3 71  ? 389.033 351.179 463.108 1.00 52.66  ? 71  SER A C   1 
ATOM 1874 O O   . SER C 3 71  ? 389.262 352.386 463.163 1.00 52.66  ? 71  SER A O   1 
ATOM 1875 C CB  . SER C 3 71  ? 390.274 350.026 461.292 1.00 52.66  ? 71  SER A CB  1 
ATOM 1876 O OG  . SER C 3 71  ? 390.669 348.861 461.975 1.00 52.66  ? 71  SER A OG  1 
ATOM 1877 N N   . ALA C 3 72  ? 388.889 350.421 464.191 1.00 52.49  ? 72  ALA A N   1 
ATOM 1878 C CA  . ALA C 3 72  ? 388.888 351.006 465.523 1.00 52.49  ? 72  ALA A CA  1 
ATOM 1879 C C   . ALA C 3 72  ? 389.334 349.984 466.553 1.00 52.49  ? 72  ALA A C   1 
ATOM 1880 O O   . ALA C 3 72  ? 388.785 348.886 466.608 1.00 52.49  ? 72  ALA A O   1 
ATOM 1881 C CB  . ALA C 3 72  ? 387.498 351.522 465.888 1.00 52.49  ? 72  ALA A CB  1 
ATOM 1882 N N   . CYS C 3 73  ? 390.309 350.354 467.379 1.00 52.11  ? 73  CYS A N   1 
ATOM 1883 C CA  . CYS C 3 73  ? 390.767 349.475 468.448 1.00 52.11  ? 73  CYS A CA  1 
ATOM 1884 C C   . CYS C 3 73  ? 389.731 349.435 469.558 1.00 52.11  ? 73  CYS A C   1 
ATOM 1885 O O   . CYS C 3 73  ? 389.418 350.464 470.160 1.00 52.11  ? 73  CYS A O   1 
ATOM 1886 C CB  . CYS C 3 73  ? 392.109 349.948 468.992 1.00 52.11  ? 73  CYS A CB  1 
ATOM 1887 S SG  . CYS C 3 73  ? 392.603 349.204 470.555 1.00 52.11  ? 73  CYS A SG  1 
ATOM 1888 N N   . VAL C 3 74  ? 389.210 348.245 469.846 1.00 51.19  ? 74  VAL A N   1 
ATOM 1889 C CA  . VAL C 3 74  ? 388.110 348.104 470.778 1.00 51.19  ? 74  VAL A CA  1 
ATOM 1890 C C   . VAL C 3 74  ? 388.517 347.447 472.090 1.00 51.19  ? 74  VAL A C   1 
ATOM 1891 O O   . VAL C 3 74  ? 387.892 347.720 473.118 1.00 51.19  ? 74  VAL A O   1 
ATOM 1892 C CB  . VAL C 3 74  ? 386.953 347.333 470.125 1.00 51.19  ? 74  VAL A CB  1 
ATOM 1893 C CG1 . VAL C 3 74  ? 386.244 348.212 469.149 1.00 51.19  ? 74  VAL A CG1 1 
ATOM 1894 C CG2 . VAL C 3 74  ? 387.475 346.132 469.424 1.00 51.19  ? 74  VAL A CG2 1 
ATOM 1895 N N   . TYR C 3 75  ? 389.541 346.609 472.106 1.00 55.26  ? 75  TYR A N   1 
ATOM 1896 C CA  . TYR C 3 75  ? 389.880 345.894 473.321 1.00 55.26  ? 75  TYR A CA  1 
ATOM 1897 C C   . TYR C 3 75  ? 391.386 345.857 473.502 1.00 55.26  ? 75  TYR A C   1 
ATOM 1898 O O   . TYR C 3 75  ? 392.143 345.974 472.542 1.00 55.26  ? 75  TYR A O   1 
ATOM 1899 C CB  . TYR C 3 75  ? 389.313 344.482 473.295 1.00 55.26  ? 75  TYR A CB  1 
ATOM 1900 C CG  . TYR C 3 75  ? 389.320 343.783 474.625 1.00 55.26  ? 75  TYR A CG  1 
ATOM 1901 C CD1 . TYR C 3 75  ? 388.868 344.413 475.764 1.00 55.26  ? 75  TYR A CD1 1 
ATOM 1902 C CD2 . TYR C 3 75  ? 389.793 342.494 474.735 1.00 55.26  ? 75  TYR A CD2 1 
ATOM 1903 C CE1 . TYR C 3 75  ? 388.881 343.775 476.971 1.00 55.26  ? 75  TYR A CE1 1 
ATOM 1904 C CE2 . TYR C 3 75  ? 389.806 341.847 475.929 1.00 55.26  ? 75  TYR A CE2 1 
ATOM 1905 C CZ  . TYR C 3 75  ? 389.357 342.488 477.045 1.00 55.26  ? 75  TYR A CZ  1 
ATOM 1906 O OH  . TYR C 3 75  ? 389.381 341.823 478.244 1.00 55.26  ? 75  TYR A OH  1 
ATOM 1907 N N   . TYR C 3 76  ? 391.810 345.691 474.751 1.00 61.57  ? 76  TYR A N   1 
ATOM 1908 C CA  . TYR C 3 76  ? 393.227 345.677 475.093 1.00 61.57  ? 76  TYR A CA  1 
ATOM 1909 C C   . TYR C 3 76  ? 393.388 344.860 476.364 1.00 61.57  ? 76  TYR A C   1 
ATOM 1910 O O   . TYR C 3 76  ? 393.024 345.331 477.442 1.00 61.57  ? 76  TYR A O   1 
ATOM 1911 C CB  . TYR C 3 76  ? 393.730 347.090 475.292 1.00 61.57  ? 76  TYR A CB  1 
ATOM 1912 C CG  . TYR C 3 76  ? 395.140 347.185 475.799 1.00 61.57  ? 76  TYR A CG  1 
ATOM 1913 C CD1 . TYR C 3 76  ? 396.209 346.980 474.950 1.00 61.57  ? 76  TYR A CD1 1 
ATOM 1914 C CD2 . TYR C 3 76  ? 395.402 347.507 477.121 1.00 61.57  ? 76  TYR A CD2 1 
ATOM 1915 C CE1 . TYR C 3 76  ? 397.500 347.074 475.398 1.00 61.57  ? 76  TYR A CE1 1 
ATOM 1916 C CE2 . TYR C 3 76  ? 396.693 347.602 477.582 1.00 61.57  ? 76  TYR A CE2 1 
ATOM 1917 C CZ  . TYR C 3 76  ? 397.740 347.386 476.712 1.00 61.57  ? 76  TYR A CZ  1 
ATOM 1918 O OH  . TYR C 3 76  ? 399.038 347.480 477.152 1.00 61.57  ? 76  TYR A OH  1 
ATOM 1919 N N   . ALA C 3 77  ? 393.931 343.653 476.250 1.00 58.68  ? 77  ALA A N   1 
ATOM 1920 C CA  . ALA C 3 77  ? 394.103 342.803 477.415 1.00 58.68  ? 77  ALA A CA  1 
ATOM 1921 C C   . ALA C 3 77  ? 395.461 342.131 477.366 1.00 58.68  ? 77  ALA A C   1 
ATOM 1922 O O   . ALA C 3 77  ? 396.065 341.989 476.305 1.00 58.68  ? 77  ALA A O   1 
ATOM 1923 C CB  . ALA C 3 77  ? 393.011 341.743 477.508 1.00 58.68  ? 77  ALA A CB  1 
ATOM 1924 N N   . THR C 3 78  ? 395.939 341.723 478.535 1.00 59.72  ? 78  THR A N   1 
ATOM 1925 C CA  . THR C 3 78  ? 397.213 341.041 478.660 1.00 59.72  ? 78  THR A CA  1 
ATOM 1926 C C   . THR C 3 78  ? 396.996 339.645 479.217 1.00 59.72  ? 78  THR A C   1 
ATOM 1927 O O   . THR C 3 78  ? 395.964 339.363 479.827 1.00 59.72  ? 78  THR A O   1 
ATOM 1928 C CB  . THR C 3 78  ? 398.177 341.776 479.581 1.00 59.72  ? 78  THR A CB  1 
ATOM 1929 O OG1 . THR C 3 78  ? 397.960 341.351 480.926 1.00 59.72  ? 78  THR A OG1 1 
ATOM 1930 C CG2 . THR C 3 78  ? 397.963 343.268 479.517 1.00 59.72  ? 78  THR A CG2 1 
ATOM 1931 N N   . TYR C 3 79  ? 397.987 338.781 479.022 1.00 56.98  ? 79  TYR A N   1 
ATOM 1932 C CA  . TYR C 3 79  ? 397.947 337.423 479.541 1.00 56.98  ? 79  TYR A CA  1 
ATOM 1933 C C   . TYR C 3 79  ? 399.358 336.869 479.571 1.00 56.98  ? 79  TYR A C   1 
ATOM 1934 O O   . TYR C 3 79  ? 400.126 337.084 478.637 1.00 56.98  ? 79  TYR A O   1 
ATOM 1935 C CB  . TYR C 3 79  ? 397.040 336.513 478.703 1.00 56.98  ? 79  TYR A CB  1 
ATOM 1936 C CG  . TYR C 3 79  ? 397.358 336.433 477.230 1.00 56.98  ? 79  TYR A CG  1 
ATOM 1937 C CD1 . TYR C 3 79  ? 396.830 337.342 476.334 1.00 56.98  ? 79  TYR A CD1 1 
ATOM 1938 C CD2 . TYR C 3 79  ? 398.148 335.423 476.733 1.00 56.98  ? 79  TYR A CD2 1 
ATOM 1939 C CE1 . TYR C 3 79  ? 397.108 337.264 474.997 1.00 56.98  ? 79  TYR A CE1 1 
ATOM 1940 C CE2 . TYR C 3 79  ? 398.430 335.342 475.401 1.00 56.98  ? 79  TYR A CE2 1 
ATOM 1941 C CZ  . TYR C 3 79  ? 397.908 336.263 474.542 1.00 56.98  ? 79  TYR A CZ  1 
ATOM 1942 O OH  . TYR C 3 79  ? 398.192 336.174 473.209 1.00 56.98  ? 79  TYR A OH  1 
ATOM 1943 N N   . THR C 3 80  ? 399.699 336.165 480.639 1.00 64.12  ? 80  THR A N   1 
ATOM 1944 C CA  . THR C 3 80  ? 401.003 335.532 480.758 1.00 64.12  ? 80  THR A CA  1 
ATOM 1945 C C   . THR C 3 80  ? 400.871 334.021 480.872 1.00 64.12  ? 80  THR A C   1 
ATOM 1946 O O   . THR C 3 80  ? 399.883 333.493 481.377 1.00 64.12  ? 80  THR A O   1 
ATOM 1947 C CB  . THR C 3 80  ? 401.763 336.103 481.949 1.00 64.12  ? 80  THR A CB  1 
ATOM 1948 O OG1 . THR C 3 80  ? 402.952 335.341 482.174 1.00 64.12  ? 80  THR A OG1 1 
ATOM 1949 C CG2 . THR C 3 80  ? 400.915 336.122 483.162 1.00 64.12  ? 80  THR A CG2 1 
ATOM 1950 N N   . ASN C 3 81  ? 401.902 333.321 480.402 1.00 66.70  ? 81  ASN A N   1 
ATOM 1951 C CA  . ASN C 3 81  ? 401.810 331.894 480.125 1.00 66.70  ? 81  ASN A CA  1 
ATOM 1952 C C   . ASN C 3 81  ? 401.903 331.014 481.361 1.00 66.70  ? 81  ASN A C   1 
ATOM 1953 O O   . ASN C 3 81  ? 401.225 329.987 481.431 1.00 66.70  ? 81  ASN A O   1 
ATOM 1954 C CB  . ASN C 3 81  ? 402.898 331.479 479.136 1.00 66.70  ? 81  ASN A CB  1 
ATOM 1955 C CG  . ASN C 3 81  ? 404.250 331.972 479.531 1.00 66.70  ? 81  ASN A CG  1 
ATOM 1956 O OD1 . ASN C 3 81  ? 404.382 332.743 480.466 1.00 66.70  ? 81  ASN A OD1 1 
ATOM 1957 N ND2 . ASN C 3 81  ? 405.269 331.549 478.808 1.00 66.70  ? 81  ASN A ND2 1 
ATOM 1958 N N   . ASN C 3 82  ? 402.711 331.379 482.344 1.00 73.59  ? 82  ASN A N   1 
ATOM 1959 C CA  . ASN C 3 82  ? 402.947 330.479 483.460 1.00 73.59  ? 82  ASN A CA  1 
ATOM 1960 C C   . ASN C 3 82  ? 402.113 330.794 484.690 1.00 73.59  ? 82  ASN A C   1 
ATOM 1961 O O   . ASN C 3 82  ? 402.272 330.115 485.708 1.00 73.59  ? 82  ASN A O   1 
ATOM 1962 C CB  . ASN C 3 82  ? 404.427 330.495 483.843 1.00 73.59  ? 82  ASN A CB  1 
ATOM 1963 C CG  . ASN C 3 82  ? 404.844 331.792 484.479 1.00 73.59  ? 82  ASN A CG  1 
ATOM 1964 O OD1 . ASN C 3 82  ? 404.399 332.859 484.078 1.00 73.59  ? 82  ASN A OD1 1 
ATOM 1965 N ND2 . ASN C 3 82  ? 405.705 331.708 485.479 1.00 73.59  ? 82  ASN A ND2 1 
ATOM 1966 N N   . SER C 3 83  ? 401.233 331.783 484.638 1.00 77.47  ? 83  SER A N   1 
ATOM 1967 C CA  . SER C 3 83  ? 400.576 332.225 485.859 1.00 77.47  ? 83  SER A CA  1 
ATOM 1968 C C   . SER C 3 83  ? 399.241 331.551 486.120 1.00 77.47  ? 83  SER A C   1 
ATOM 1969 O O   . SER C 3 83  ? 398.571 331.956 487.072 1.00 77.47  ? 83  SER A O   1 
ATOM 1970 C CB  . SER C 3 83  ? 400.371 333.737 485.839 1.00 77.47  ? 83  SER A CB  1 
ATOM 1971 O OG  . SER C 3 83  ? 401.545 334.426 486.235 1.00 77.47  ? 83  SER A OG  1 
ATOM 1972 N N   . LYS C 3 84  ? 398.808 330.617 485.266 1.00 79.67  ? 84  LYS A N   1 
ATOM 1973 C CA  . LYS C 3 84  ? 397.639 329.739 485.432 1.00 79.67  ? 84  LYS A CA  1 
ATOM 1974 C C   . LYS C 3 84  ? 396.288 330.463 485.512 1.00 79.67  ? 84  LYS A C   1 
ATOM 1975 O O   . LYS C 3 84  ? 395.236 329.822 485.612 1.00 79.67  ? 84  LYS A O   1 
ATOM 1976 C CB  . LYS C 3 84  ? 397.853 328.801 486.640 1.00 79.67  ? 84  LYS A CB  1 
ATOM 1977 C CG  . LYS C 3 84  ? 397.267 329.207 487.992 1.00 79.67  ? 84  LYS A CG  1 
ATOM 1978 C CD  . LYS C 3 84  ? 397.606 328.191 489.054 1.00 79.67  ? 84  LYS A CD  1 
ATOM 1979 C CE  . LYS C 3 84  ? 399.086 328.240 489.391 1.00 79.67  ? 84  LYS A CE  1 
ATOM 1980 N NZ  . LYS C 3 84  ? 399.505 329.553 489.960 1.00 79.67  ? 84  LYS A NZ  1 
ATOM 1981 N N   . LYS C 3 85  ? 396.293 331.788 485.388 1.00 76.60  ? 85  LYS A N   1 
ATOM 1982 C CA  . LYS C 3 85  ? 395.092 332.602 485.271 1.00 76.60  ? 85  LYS A CA  1 
ATOM 1983 C C   . LYS C 3 85  ? 395.292 333.678 484.212 1.00 76.60  ? 85  LYS A C   1 
ATOM 1984 O O   . LYS C 3 85  ? 394.628 334.719 484.241 1.00 76.60  ? 85  LYS A O   1 
ATOM 1985 C CB  . LYS C 3 85  ? 394.733 333.221 486.612 1.00 76.60  ? 85  LYS A CB  1 
ATOM 1986 C CG  . LYS C 3 85  ? 395.921 333.899 487.235 1.00 76.60  ? 85  LYS A CG  1 
ATOM 1987 C CD  . LYS C 3 85  ? 395.760 334.116 488.716 1.00 76.60  ? 85  LYS A CD  1 
ATOM 1988 C CE  . LYS C 3 85  ? 397.090 334.524 489.312 1.00 76.60  ? 85  LYS A CE  1 
ATOM 1989 N NZ  . LYS C 3 85  ? 398.103 333.451 489.104 1.00 76.60  ? 85  LYS A NZ  1 
ATOM 1990 N N   . GLY C 3 86  ? 396.226 333.450 483.292 1.00 62.97  ? 86  GLY A N   1 
ATOM 1991 C CA  . GLY C 3 86  ? 396.420 334.314 482.155 1.00 62.97  ? 86  GLY A CA  1 
ATOM 1992 C C   . GLY C 3 86  ? 395.875 333.731 480.869 1.00 62.97  ? 86  GLY A C   1 
ATOM 1993 O O   . GLY C 3 86  ? 396.473 332.822 480.291 1.00 62.97  ? 86  GLY A O   1 
ATOM 1994 N N   . PHE C 3 87  ? 394.724 334.243 480.437 1.00 58.51  ? 87  PHE A N   1 
ATOM 1995 C CA  . PHE C 3 87  ? 394.163 334.045 479.108 1.00 58.51  ? 87  PHE A CA  1 
ATOM 1996 C C   . PHE C 3 87  ? 393.123 335.136 478.901 1.00 58.51  ? 87  PHE A C   1 
ATOM 1997 O O   . PHE C 3 87  ? 392.406 335.492 479.836 1.00 58.51  ? 87  PHE A O   1 
ATOM 1998 C CB  . PHE C 3 87  ? 393.554 332.647 478.924 1.00 58.51  ? 87  PHE A CB  1 
ATOM 1999 C CG  . PHE C 3 87  ? 392.291 332.408 479.693 1.00 58.51  ? 87  PHE A CG  1 
ATOM 2000 C CD1 . PHE C 3 87  ? 392.327 332.126 481.042 1.00 58.51  ? 87  PHE A CD1 1 
ATOM 2001 C CD2 . PHE C 3 87  ? 391.068 332.422 479.055 1.00 58.51  ? 87  PHE A CD2 1 
ATOM 2002 C CE1 . PHE C 3 87  ? 391.172 331.897 481.737 1.00 58.51  ? 87  PHE A CE1 1 
ATOM 2003 C CE2 . PHE C 3 87  ? 389.912 332.195 479.750 1.00 58.51  ? 87  PHE A CE2 1 
ATOM 2004 C CZ  . PHE C 3 87  ? 389.965 331.931 481.088 1.00 58.51  ? 87  PHE A CZ  1 
ATOM 2005 N N   . ALA C 3 88  ? 393.066 335.685 477.695 1.00 56.34  ? 88  ALA A N   1 
ATOM 2006 C CA  . ALA C 3 88  ? 392.228 336.845 477.446 1.00 56.34  ? 88  ALA A CA  1 
ATOM 2007 C C   . ALA C 3 88  ? 390.819 336.414 477.061 1.00 56.34  ? 88  ALA A C   1 
ATOM 2008 O O   . ALA C 3 88  ? 390.567 335.259 476.731 1.00 56.34  ? 88  ALA A O   1 
ATOM 2009 C CB  . ALA C 3 88  ? 392.849 337.719 476.367 1.00 56.34  ? 88  ALA A CB  1 
ATOM 2010 N N   . GLU C 3 89  ? 389.887 337.364 477.078 1.00 55.61  ? 89  GLU A N   1 
ATOM 2011 C CA  . GLU C 3 89  ? 388.475 337.064 476.886 1.00 55.61  ? 89  GLU A CA  1 
ATOM 2012 C C   . GLU C 3 89  ? 387.742 338.348 476.537 1.00 55.61  ? 89  GLU A C   1 
ATOM 2013 O O   . GLU C 3 89  ? 387.915 339.355 477.225 1.00 55.61  ? 89  GLU A O   1 
ATOM 2014 C CB  . GLU C 3 89  ? 387.892 336.440 478.152 1.00 55.61  ? 89  GLU A CB  1 
ATOM 2015 C CG  . GLU C 3 89  ? 386.397 336.525 478.275 1.00 55.61  ? 89  GLU A CG  1 
ATOM 2016 C CD  . GLU C 3 89  ? 385.912 336.124 479.650 1.00 55.61  ? 89  GLU A CD  1 
ATOM 2017 O OE1 . GLU C 3 89  ? 386.760 335.928 480.543 1.00 55.61  ? 89  GLU A OE1 1 
ATOM 2018 O OE2 . GLU C 3 89  ? 384.686 336.002 479.840 1.00 55.61  ? 89  GLU A OE2 1 
ATOM 2019 N N   . TRP C 3 90  ? 386.930 338.321 475.483 1.00 52.90  ? 90  TRP A N   1 
ATOM 2020 C CA  . TRP C 3 90  ? 386.189 339.517 475.089 1.00 52.90  ? 90  TRP A CA  1 
ATOM 2021 C C   . TRP C 3 90  ? 384.874 339.112 474.457 1.00 52.90  ? 90  TRP A C   1 
ATOM 2022 O O   . TRP C 3 90  ? 384.870 338.514 473.382 1.00 52.90  ? 90  TRP A O   1 
ATOM 2023 C CB  . TRP C 3 90  ? 386.983 340.359 474.115 1.00 52.90  ? 90  TRP A CB  1 
ATOM 2024 C CG  . TRP C 3 90  ? 386.288 341.622 473.743 1.00 52.90  ? 90  TRP A CG  1 
ATOM 2025 C CD1 . TRP C 3 90  ? 385.844 342.582 474.589 1.00 52.90  ? 90  TRP A CD1 1 
ATOM 2026 C CD2 . TRP C 3 90  ? 385.958 342.068 472.428 1.00 52.90  ? 90  TRP A CD2 1 
ATOM 2027 N NE1 . TRP C 3 90  ? 385.255 343.595 473.889 1.00 52.90  ? 90  TRP A NE1 1 
ATOM 2028 C CE2 . TRP C 3 90  ? 385.314 343.301 472.557 1.00 52.90  ? 90  TRP A CE2 1 
ATOM 2029 C CE3 . TRP C 3 90  ? 386.141 341.538 471.154 1.00 52.90  ? 90  TRP A CE3 1 
ATOM 2030 C CZ2 . TRP C 3 90  ? 384.851 344.008 471.471 1.00 52.90  ? 90  TRP A CZ2 1 
ATOM 2031 C CZ3 . TRP C 3 90  ? 385.680 342.248 470.078 1.00 52.90  ? 90  TRP A CZ3 1 
ATOM 2032 C CH2 . TRP C 3 90  ? 385.045 343.466 470.242 1.00 52.90  ? 90  TRP A CH2 1 
ATOM 2033 N N   . VAL C 3 91  ? 383.766 339.458 475.100 1.00 52.99  ? 91  VAL A N   1 
ATOM 2034 C CA  . VAL C 3 91  ? 382.442 339.237 474.531 1.00 52.99  ? 91  VAL A CA  1 
ATOM 2035 C C   . VAL C 3 91  ? 382.164 340.341 473.525 1.00 52.99  ? 91  VAL A C   1 
ATOM 2036 O O   . VAL C 3 91  ? 382.189 341.522 473.877 1.00 52.99  ? 91  VAL A O   1 
ATOM 2037 C CB  . VAL C 3 91  ? 381.376 339.215 475.626 1.00 52.99  ? 91  VAL A CB  1 
ATOM 2038 C CG1 . VAL C 3 91  ? 380.108 338.640 475.086 1.00 52.99  ? 91  VAL A CG1 1 
ATOM 2039 C CG2 . VAL C 3 91  ? 381.867 338.409 476.795 1.00 52.99  ? 91  VAL A CG2 1 
ATOM 2040 N N   . ILE C 3 92  ? 381.888 339.960 472.281 1.00 52.94  ? 92  ILE A N   1 
ATOM 2041 C CA  . ILE C 3 92  ? 381.842 340.923 471.187 1.00 52.94  ? 92  ILE A CA  1 
ATOM 2042 C C   . ILE C 3 92  ? 380.595 341.784 471.304 1.00 52.94  ? 92  ILE A C   1 
ATOM 2043 O O   . ILE C 3 92  ? 379.475 341.313 471.089 1.00 52.94  ? 92  ILE A O   1 
ATOM 2044 C CB  . ILE C 3 92  ? 381.881 340.222 469.828 1.00 52.94  ? 92  ILE A CB  1 
ATOM 2045 C CG1 . ILE C 3 92  ? 383.102 339.325 469.713 1.00 52.94  ? 92  ILE A CG1 1 
ATOM 2046 C CG2 . ILE C 3 92  ? 381.891 341.251 468.733 1.00 52.94  ? 92  ILE A CG2 1 
ATOM 2047 C CD1 . ILE C 3 92  ? 383.234 338.679 468.358 1.00 52.94  ? 92  ILE A CD1 1 
ATOM 2048 N N   . ASN C 3 93  ? 380.788 343.057 471.629 1.00 57.68  ? 93  ASN A N   1 
ATOM 2049 C CA  . ASN C 3 93  ? 379.707 344.021 471.709 1.00 57.68  ? 93  ASN A CA  1 
ATOM 2050 C C   . ASN C 3 93  ? 380.171 345.317 471.074 1.00 57.68  ? 93  ASN A C   1 
ATOM 2051 O O   . ASN C 3 93  ? 381.361 345.635 471.062 1.00 57.68  ? 93  ASN A O   1 
ATOM 2052 C CB  . ASN C 3 93  ? 379.281 344.261 473.153 1.00 57.68  ? 93  ASN A CB  1 
ATOM 2053 C CG  . ASN C 3 93  ? 380.410 344.760 473.999 1.00 57.68  ? 93  ASN A CG  1 
ATOM 2054 O OD1 . ASN C 3 93  ? 381.567 344.493 473.715 1.00 57.68  ? 93  ASN A OD1 1 
ATOM 2055 N ND2 . ASN C 3 93  ? 380.084 345.478 475.058 1.00 57.68  ? 93  ASN A ND2 1 
ATOM 2056 N N   . THR C 3 94  ? 379.220 346.081 470.554 1.00 59.90  ? 94  THR A N   1 
ATOM 2057 C CA  . THR C 3 94  ? 379.534 347.349 469.921 1.00 59.90  ? 94  THR A CA  1 
ATOM 2058 C C   . THR C 3 94  ? 379.622 348.503 470.904 1.00 59.90  ? 94  THR A C   1 
ATOM 2059 O O   . THR C 3 94  ? 380.001 349.604 470.507 1.00 59.90  ? 94  THR A O   1 
ATOM 2060 C CB  . THR C 3 94  ? 378.488 347.672 468.865 1.00 59.90  ? 94  THR A CB  1 
ATOM 2061 O OG1 . THR C 3 94  ? 377.272 348.052 469.512 1.00 59.90  ? 94  THR A OG1 1 
ATOM 2062 C CG2 . THR C 3 94  ? 378.237 346.461 468.007 1.00 59.90  ? 94  THR A CG2 1 
ATOM 2063 N N   . ARG C 3 95  ? 379.309 348.273 472.173 1.00 62.81  ? 95  ARG A N   1 
ATOM 2064 C CA  . ARG C 3 95  ? 379.234 349.324 473.174 1.00 62.81  ? 95  ARG A CA  1 
ATOM 2065 C C   . ARG C 3 95  ? 380.501 349.448 473.993 1.00 62.81  ? 95  ARG A C   1 
ATOM 2066 O O   . ARG C 3 95  ? 380.437 349.796 475.172 1.00 62.81  ? 95  ARG A O   1 
ATOM 2067 C CB  . ARG C 3 95  ? 378.037 349.072 474.085 1.00 62.81  ? 95  ARG A CB  1 
ATOM 2068 C CG  . ARG C 3 95  ? 376.739 348.958 473.326 1.00 62.81  ? 95  ARG A CG  1 
ATOM 2069 C CD  . ARG C 3 95  ? 375.646 348.347 474.162 1.00 62.81  ? 95  ARG A CD  1 
ATOM 2070 N NE  . ARG C 3 95  ? 374.368 348.977 473.866 1.00 62.81  ? 95  ARG A NE  1 
ATOM 2071 C CZ  . ARG C 3 95  ? 373.219 348.652 474.441 1.00 62.81  ? 95  ARG A CZ  1 
ATOM 2072 N NH1 . ARG C 3 95  ? 373.177 347.692 475.349 1.00 62.81  ? 95  ARG A NH1 1 
ATOM 2073 N NH2 . ARG C 3 95  ? 372.110 349.290 474.105 1.00 62.81  ? 95  ARG A NH2 1 
ATOM 2074 N N   . GLN C 3 96  ? 381.659 349.182 473.401 1.00 61.63  ? 96  GLN A N   1 
ATOM 2075 C CA  . GLN C 3 96  ? 382.905 349.162 474.158 1.00 61.63  ? 96  GLN A CA  1 
ATOM 2076 C C   . GLN C 3 96  ? 383.572 350.533 474.171 1.00 61.63  ? 96  GLN A C   1 
ATOM 2077 O O   . GLN C 3 96  ? 383.812 351.105 475.238 1.00 61.63  ? 96  GLN A O   1 
ATOM 2078 C CB  . GLN C 3 96  ? 383.844 348.103 473.576 1.00 61.63  ? 96  GLN A CB  1 
ATOM 2079 C CG  . GLN C 3 96  ? 384.906 347.650 474.529 1.00 61.63  ? 96  GLN A CG  1 
ATOM 2080 C CD  . GLN C 3 96  ? 384.328 346.991 475.748 1.00 61.63  ? 96  GLN A CD  1 
ATOM 2081 O OE1 . GLN C 3 96  ? 384.269 347.585 476.820 1.00 61.63  ? 96  GLN A OE1 1 
ATOM 2082 N NE2 . GLN C 3 96  ? 383.888 345.757 475.593 1.00 61.63  ? 96  GLN A NE2 1 
ATOM 2083 N N   . VAL C 3 97  ? 383.877 351.063 472.997 1.00 59.42  ? 97  VAL A N   1 
ATOM 2084 C CA  . VAL C 3 97  ? 384.455 352.390 472.853 1.00 59.42  ? 97  VAL A CA  1 
ATOM 2085 C C   . VAL C 3 97  ? 383.336 353.387 472.586 1.00 59.42  ? 97  VAL A C   1 
ATOM 2086 O O   . VAL C 3 97  ? 382.419 353.140 471.797 1.00 59.42  ? 97  VAL A O   1 
ATOM 2087 C CB  . VAL C 3 97  ? 385.544 352.390 471.756 1.00 59.42  ? 97  VAL A CB  1 
ATOM 2088 C CG1 . VAL C 3 97  ? 385.025 351.823 470.470 1.00 59.42  ? 97  VAL A CG1 1 
ATOM 2089 C CG2 . VAL C 3 97  ? 386.081 353.780 471.519 1.00 59.42  ? 97  VAL A CG2 1 
ATOM 2090 N N   . ALA C 3 98  ? 383.383 354.510 473.300 1.00 60.79  ? 98  ALA A N   1 
ATOM 2091 C CA  . ALA C 3 98  ? 382.287 355.465 473.286 1.00 60.79  ? 98  ALA A CA  1 
ATOM 2092 C C   . ALA C 3 98  ? 382.195 356.262 471.998 1.00 60.79  ? 98  ALA A C   1 
ATOM 2093 O O   . ALA C 3 98  ? 381.131 356.805 471.704 1.00 60.79  ? 98  ALA A O   1 
ATOM 2094 C CB  . ALA C 3 98  ? 382.422 356.426 474.463 1.00 60.79  ? 98  ALA A CB  1 
ATOM 2095 N N   . GLN C 3 99  ? 383.268 356.357 471.225 1.00 60.65  ? 99  GLN A N   1 
ATOM 2096 C CA  . GLN C 3 99  ? 383.188 357.134 470.000 1.00 60.65  ? 99  GLN A CA  1 
ATOM 2097 C C   . GLN C 3 99  ? 382.542 356.344 468.875 1.00 60.65  ? 99  GLN A C   1 
ATOM 2098 O O   . GLN C 3 99  ? 381.781 356.903 468.084 1.00 60.65  ? 99  GLN A O   1 
ATOM 2099 C CB  . GLN C 3 99  ? 384.575 357.607 469.594 1.00 60.65  ? 99  GLN A CB  1 
ATOM 2100 C CG  . GLN C 3 99  ? 384.980 358.910 470.242 1.00 60.65  ? 99  GLN A CG  1 
ATOM 2101 C CD  . GLN C 3 99  ? 384.630 360.115 469.400 1.00 60.65  ? 99  GLN A CD  1 
ATOM 2102 O OE1 . GLN C 3 99  ? 383.845 360.025 468.465 1.00 60.65  ? 99  GLN A OE1 1 
ATOM 2103 N NE2 . GLN C 3 99  ? 385.213 361.250 469.731 1.00 60.65  ? 99  GLN A NE2 1 
ATOM 2104 N N   . LEU C 3 100 ? 382.835 355.049 468.779 1.00 56.96  ? 100 LEU A N   1 
ATOM 2105 C CA  . LEU C 3 100 ? 382.174 354.216 467.783 1.00 56.96  ? 100 LEU A CA  1 
ATOM 2106 C C   . LEU C 3 100 ? 380.729 353.946 468.158 1.00 56.96  ? 100 LEU A C   1 
ATOM 2107 O O   . LEU C 3 100 ? 379.876 353.847 467.273 1.00 56.96  ? 100 LEU A O   1 
ATOM 2108 C CB  . LEU C 3 100 ? 382.931 352.903 467.611 1.00 56.96  ? 100 LEU A CB  1 
ATOM 2109 C CG  . LEU C 3 100 ? 382.290 351.747 466.848 1.00 56.96  ? 100 LEU A CG  1 
ATOM 2110 C CD1 . LEU C 3 100 ? 382.071 352.133 465.408 1.00 56.96  ? 100 LEU A CD1 1 
ATOM 2111 C CD2 . LEU C 3 100 ? 383.135 350.499 466.943 1.00 56.96  ? 100 LEU A CD2 1 
ATOM 2112 N N   . ARG C 3 101 ? 380.437 353.849 469.456 1.00 57.47  ? 101 ARG A N   1 
ATOM 2113 C CA  . ARG C 3 101 ? 379.082 353.563 469.918 1.00 57.47  ? 101 ARG A CA  1 
ATOM 2114 C C   . ARG C 3 101 ? 378.120 354.679 469.553 1.00 57.47  ? 101 ARG A C   1 
ATOM 2115 O O   . ARG C 3 101 ? 376.990 354.415 469.140 1.00 57.47  ? 101 ARG A O   1 
ATOM 2116 C CB  . ARG C 3 101 ? 379.090 353.344 471.424 1.00 57.47  ? 101 ARG A CB  1 
ATOM 2117 C CG  . ARG C 3 101 ? 377.746 353.105 472.038 1.00 57.47  ? 101 ARG A CG  1 
ATOM 2118 C CD  . ARG C 3 101 ? 377.887 352.851 473.514 1.00 57.47  ? 101 ARG A CD  1 
ATOM 2119 N NE  . ARG C 3 101 ? 376.595 352.660 474.150 1.00 57.47  ? 101 ARG A NE  1 
ATOM 2120 C CZ  . ARG C 3 101 ? 376.416 352.606 475.460 1.00 57.47  ? 101 ARG A CZ  1 
ATOM 2121 N NH1 . ARG C 3 101 ? 377.448 352.734 476.272 1.00 57.47  ? 101 ARG A NH1 1 
ATOM 2122 N NH2 . ARG C 3 101 ? 375.207 352.438 475.955 1.00 57.47  ? 101 ARG A NH2 1 
ATOM 2123 N N   . ARG C 3 102 ? 378.565 355.928 469.652 1.00 57.39  ? 102 ARG A N   1 
ATOM 2124 C CA  . ARG C 3 102 ? 377.709 357.058 469.321 1.00 57.39  ? 102 ARG A CA  1 
ATOM 2125 C C   . ARG C 3 102 ? 377.418 357.128 467.831 1.00 57.39  ? 102 ARG A C   1 
ATOM 2126 O O   . ARG C 3 102 ? 376.405 357.703 467.430 1.00 57.39  ? 102 ARG A O   1 
ATOM 2127 C CB  . ARG C 3 102 ? 378.364 358.347 469.797 1.00 57.39  ? 102 ARG A CB  1 
ATOM 2128 C CG  . ARG C 3 102 ? 377.439 359.516 469.945 1.00 57.39  ? 102 ARG A CG  1 
ATOM 2129 C CD  . ARG C 3 102 ? 378.236 360.777 470.109 1.00 57.39  ? 102 ARG A CD  1 
ATOM 2130 N NE  . ARG C 3 102 ? 377.394 361.940 470.338 1.00 57.39  ? 102 ARG A NE  1 
ATOM 2131 C CZ  . ARG C 3 102 ? 376.968 362.752 469.383 1.00 57.39  ? 102 ARG A CZ  1 
ATOM 2132 N NH1 . ARG C 3 102 ? 377.298 362.529 468.125 1.00 57.39  ? 102 ARG A NH1 1 
ATOM 2133 N NH2 . ARG C 3 102 ? 376.209 363.787 469.688 1.00 57.39  ? 102 ARG A NH2 1 
ATOM 2134 N N   . LYS C 3 103 ? 378.281 356.552 466.999 1.00 54.77  ? 103 LYS A N   1 
ATOM 2135 C CA  . LYS C 3 103 ? 378.022 356.512 465.569 1.00 54.77  ? 103 LYS A CA  1 
ATOM 2136 C C   . LYS C 3 103 ? 377.077 355.392 465.187 1.00 54.77  ? 103 LYS A C   1 
ATOM 2137 O O   . LYS C 3 103 ? 376.245 355.578 464.300 1.00 54.77  ? 103 LYS A O   1 
ATOM 2138 C CB  . LYS C 3 103 ? 379.327 356.354 464.796 1.00 54.77  ? 103 LYS A CB  1 
ATOM 2139 C CG  . LYS C 3 103 ? 380.324 357.440 465.084 1.00 54.77  ? 103 LYS A CG  1 
ATOM 2140 C CD  . LYS C 3 103 ? 381.635 357.196 464.391 1.00 54.77  ? 103 LYS A CD  1 
ATOM 2141 C CE  . LYS C 3 103 ? 381.485 357.273 462.910 1.00 54.77  ? 103 LYS A CE  1 
ATOM 2142 N NZ  . LYS C 3 103 ? 382.689 356.734 462.246 1.00 54.77  ? 103 LYS A NZ  1 
ATOM 2143 N N   . LEU C 3 104 ? 377.176 354.240 465.831 1.00 54.73  ? 104 LEU A N   1 
ATOM 2144 C CA  . LEU C 3 104 ? 376.275 353.145 465.531 1.00 54.73  ? 104 LEU A CA  1 
ATOM 2145 C C   . LEU C 3 104 ? 374.898 353.347 466.128 1.00 54.73  ? 104 LEU A C   1 
ATOM 2146 O O   . LEU C 3 104 ? 373.942 352.728 465.659 1.00 54.73  ? 104 LEU A O   1 
ATOM 2147 C CB  . LEU C 3 104 ? 376.856 351.823 466.037 1.00 54.73  ? 104 LEU A CB  1 
ATOM 2148 C CG  . LEU C 3 104 ? 378.167 351.365 465.410 1.00 54.73  ? 104 LEU A CG  1 
ATOM 2149 C CD1 . LEU C 3 104 ? 378.782 350.324 466.269 1.00 54.73  ? 104 LEU A CD1 1 
ATOM 2150 C CD2 . LEU C 3 104 ? 377.954 350.806 464.039 1.00 54.73  ? 104 LEU A CD2 1 
ATOM 2151 N N   . GLU C 3 105 ? 374.769 354.195 467.139 1.00 58.06  ? 105 GLU A N   1 
ATOM 2152 C CA  . GLU C 3 105 ? 373.481 354.518 467.724 1.00 58.06  ? 105 GLU A CA  1 
ATOM 2153 C C   . GLU C 3 105 ? 372.799 355.688 467.041 1.00 58.06  ? 105 GLU A C   1 
ATOM 2154 O O   . GLU C 3 105 ? 371.971 356.350 467.666 1.00 58.06  ? 105 GLU A O   1 
ATOM 2155 C CB  . GLU C 3 105 ? 373.635 354.828 469.205 1.00 58.06  ? 105 GLU A CB  1 
ATOM 2156 C CG  . GLU C 3 105 ? 373.939 353.638 470.065 1.00 58.06  ? 105 GLU A CG  1 
ATOM 2157 C CD  . GLU C 3 105 ? 373.988 354.002 471.530 1.00 58.06  ? 105 GLU A CD  1 
ATOM 2158 O OE1 . GLU C 3 105 ? 373.905 353.086 472.370 1.00 58.06  ? 105 GLU A OE1 1 
ATOM 2159 O OE2 . GLU C 3 105 ? 374.105 355.206 471.843 1.00 58.06  ? 105 GLU A OE2 1 
ATOM 2160 N N   . LEU C 3 106 ? 373.154 355.992 465.798 1.00 54.29  ? 106 LEU A N   1 
ATOM 2161 C CA  . LEU C 3 106 ? 372.333 356.905 465.022 1.00 54.29  ? 106 LEU A CA  1 
ATOM 2162 C C   . LEU C 3 106 ? 371.255 356.154 464.275 1.00 54.29  ? 106 LEU A C   1 
ATOM 2163 O O   . LEU C 3 106 ? 370.378 356.773 463.671 1.00 54.29  ? 106 LEU A O   1 
ATOM 2164 C CB  . LEU C 3 106 ? 373.171 357.685 464.023 1.00 54.29  ? 106 LEU A CB  1 
ATOM 2165 C CG  . LEU C 3 106 ? 374.334 358.541 464.491 1.00 54.29  ? 106 LEU A CG  1 
ATOM 2166 C CD1 . LEU C 3 106 ? 374.695 359.494 463.384 1.00 54.29  ? 106 LEU A CD1 1 
ATOM 2167 C CD2 . LEU C 3 106 ? 373.987 359.292 465.740 1.00 54.29  ? 106 LEU A CD2 1 
ATOM 2168 N N   . PHE C 3 107 ? 371.317 354.831 464.282 1.00 53.32  ? 107 PHE A N   1 
ATOM 2169 C CA  . PHE C 3 107 ? 370.392 353.990 463.551 1.00 53.32  ? 107 PHE A CA  1 
ATOM 2170 C C   . PHE C 3 107 ? 369.819 352.943 464.485 1.00 53.32  ? 107 PHE A C   1 
ATOM 2171 O O   . PHE C 3 107 ? 370.467 352.518 465.440 1.00 53.32  ? 107 PHE A O   1 
ATOM 2172 C CB  . PHE C 3 107 ? 371.085 353.311 462.379 1.00 53.32  ? 107 PHE A CB  1 
ATOM 2173 C CG  . PHE C 3 107 ? 371.868 354.247 461.527 1.00 53.32  ? 107 PHE A CG  1 
ATOM 2174 C CD1 . PHE C 3 107 ? 371.240 354.997 460.558 1.00 53.32  ? 107 PHE A CD1 1 
ATOM 2175 C CD2 . PHE C 3 107 ? 373.230 354.381 461.693 1.00 53.32  ? 107 PHE A CD2 1 
ATOM 2176 C CE1 . PHE C 3 107 ? 371.947 355.853 459.777 1.00 53.32  ? 107 PHE A CE1 1 
ATOM 2177 C CE2 . PHE C 3 107 ? 373.941 355.243 460.914 1.00 53.32  ? 107 PHE A CE2 1 
ATOM 2178 C CZ  . PHE C 3 107 ? 373.299 355.980 459.958 1.00 53.32  ? 107 PHE A CZ  1 
ATOM 2179 N N   . THR C 3 108 ? 368.595 352.517 464.202 1.00 53.10  ? 108 THR A N   1 
ATOM 2180 C CA  . THR C 3 108 ? 367.955 351.509 465.031 1.00 53.10  ? 108 THR A CA  1 
ATOM 2181 C C   . THR C 3 108 ? 368.404 350.104 464.672 1.00 53.10  ? 108 THR A C   1 
ATOM 2182 O O   . THR C 3 108 ? 368.808 349.344 465.549 1.00 53.10  ? 108 THR A O   1 
ATOM 2183 C CB  . THR C 3 108 ? 366.437 351.605 464.920 1.00 53.10  ? 108 THR A CB  1 
ATOM 2184 O OG1 . THR C 3 108 ? 366.037 352.969 465.046 1.00 53.10  ? 108 THR A OG1 1 
ATOM 2185 C CG2 . THR C 3 108 ? 365.797 350.819 466.015 1.00 53.10  ? 108 THR A CG2 1 
ATOM 2186 N N   . TYR C 3 109 ? 368.366 349.747 463.397 1.00 54.84  ? 109 TYR A N   1 
ATOM 2187 C CA  . TYR C 3 109 ? 368.719 348.410 462.954 1.00 54.84  ? 109 TYR A CA  1 
ATOM 2188 C C   . TYR C 3 109 ? 369.932 348.476 462.045 1.00 54.84  ? 109 TYR A C   1 
ATOM 2189 O O   . TYR C 3 109 ? 369.950 349.248 461.087 1.00 54.84  ? 109 TYR A O   1 
ATOM 2190 C CB  . TYR C 3 109 ? 367.550 347.753 462.227 1.00 54.84  ? 109 TYR A CB  1 
ATOM 2191 C CG  . TYR C 3 109 ? 366.313 347.663 463.069 1.00 54.84  ? 109 TYR A CG  1 
ATOM 2192 C CD1 . TYR C 3 109 ? 366.272 346.845 464.176 1.00 54.84  ? 109 TYR A CD1 1 
ATOM 2193 C CD2 . TYR C 3 109 ? 365.190 348.405 462.761 1.00 54.84  ? 109 TYR A CD2 1 
ATOM 2194 C CE1 . TYR C 3 109 ? 365.154 346.765 464.943 1.00 54.84  ? 109 TYR A CE1 1 
ATOM 2195 C CE2 . TYR C 3 109 ? 364.071 348.333 463.528 1.00 54.84  ? 109 TYR A CE2 1 
ATOM 2196 C CZ  . TYR C 3 109 ? 364.059 347.512 464.616 1.00 54.84  ? 109 TYR A CZ  1 
ATOM 2197 O OH  . TYR C 3 109 ? 362.936 347.433 465.391 1.00 54.84  ? 109 TYR A OH  1 
ATOM 2198 N N   . LEU C 3 110 ? 370.935 347.668 462.345 1.00 54.21  ? 110 LEU A N   1 
ATOM 2199 C CA  . LEU C 3 110 ? 372.141 347.584 461.546 1.00 54.21  ? 110 LEU A CA  1 
ATOM 2200 C C   . LEU C 3 110 ? 372.341 346.160 461.060 1.00 54.21  ? 110 LEU A C   1 
ATOM 2201 O O   . LEU C 3 110 ? 371.835 345.204 461.644 1.00 54.21  ? 110 LEU A O   1 
ATOM 2202 C CB  . LEU C 3 110 ? 373.356 348.030 462.347 1.00 54.21  ? 110 LEU A CB  1 
ATOM 2203 C CG  . LEU C 3 110 ? 373.502 349.527 462.494 1.00 54.21  ? 110 LEU A CG  1 
ATOM 2204 C CD1 . LEU C 3 110 ? 374.403 349.792 463.639 1.00 54.21  ? 110 LEU A CD1 1 
ATOM 2205 C CD2 . LEU C 3 110 ? 374.089 350.084 461.238 1.00 54.21  ? 110 LEU A CD2 1 
ATOM 2206 N N   . ARG C 3 111 ? 373.106 346.025 459.984 1.00 55.60  ? 111 ARG A N   1 
ATOM 2207 C CA  . ARG C 3 111 ? 373.400 344.712 459.425 1.00 55.60  ? 111 ARG A CA  1 
ATOM 2208 C C   . ARG C 3 111 ? 374.740 344.822 458.719 1.00 55.60  ? 111 ARG A C   1 
ATOM 2209 O O   . ARG C 3 111 ? 374.864 345.584 457.760 1.00 55.60  ? 111 ARG A O   1 
ATOM 2210 C CB  . ARG C 3 111 ? 372.305 344.277 458.472 1.00 55.60  ? 111 ARG A CB  1 
ATOM 2211 C CG  . ARG C 3 111 ? 372.412 342.855 458.040 1.00 55.60  ? 111 ARG A CG  1 
ATOM 2212 C CD  . ARG C 3 111 ? 371.506 342.547 456.885 1.00 55.60  ? 111 ARG A CD  1 
ATOM 2213 N NE  . ARG C 3 111 ? 371.826 341.248 456.314 1.00 55.60  ? 111 ARG A NE  1 
ATOM 2214 C CZ  . ARG C 3 111 ? 371.142 340.139 456.557 1.00 55.60  ? 111 ARG A CZ  1 
ATOM 2215 N NH1 . ARG C 3 111 ? 370.090 340.170 457.349 1.00 55.60  ? 111 ARG A NH1 1 
ATOM 2216 N NH2 . ARG C 3 111 ? 371.505 338.999 455.999 1.00 55.60  ? 111 ARG A NH2 1 
ATOM 2217 N N   . PHE C 3 112 ? 375.738 344.083 459.191 1.00 53.66  ? 112 PHE A N   1 
ATOM 2218 C CA  . PHE C 3 112 ? 377.072 344.206 458.633 1.00 53.66  ? 112 PHE A CA  1 
ATOM 2219 C C   . PHE C 3 112 ? 377.830 342.903 458.803 1.00 53.66  ? 112 PHE A C   1 
ATOM 2220 O O   . PHE C 3 112 ? 377.507 342.083 459.659 1.00 53.66  ? 112 PHE A O   1 
ATOM 2221 C CB  . PHE C 3 112 ? 377.856 345.351 459.282 1.00 53.66  ? 112 PHE A CB  1 
ATOM 2222 C CG  . PHE C 3 112 ? 377.830 345.355 460.783 1.00 53.66  ? 112 PHE A CG  1 
ATOM 2223 C CD1 . PHE C 3 112 ? 378.760 344.648 461.511 1.00 53.66  ? 112 PHE A CD1 1 
ATOM 2224 C CD2 . PHE C 3 112 ? 376.907 346.109 461.465 1.00 53.66  ? 112 PHE A CD2 1 
ATOM 2225 C CE1 . PHE C 3 112 ? 378.745 344.662 462.877 1.00 53.66  ? 112 PHE A CE1 1 
ATOM 2226 C CE2 . PHE C 3 112 ? 376.891 346.125 462.834 1.00 53.66  ? 112 PHE A CE2 1 
ATOM 2227 C CZ  . PHE C 3 112 ? 377.811 345.402 463.536 1.00 53.66  ? 112 PHE A CZ  1 
ATOM 2228 N N   . ASP C 3 113 ? 378.849 342.728 457.972 1.00 57.32  ? 113 ASP A N   1 
ATOM 2229 C CA  . ASP C 3 113 ? 379.833 341.684 458.180 1.00 57.32  ? 113 ASP A CA  1 
ATOM 2230 C C   . ASP C 3 113 ? 380.858 342.173 459.189 1.00 57.32  ? 113 ASP A C   1 
ATOM 2231 O O   . ASP C 3 113 ? 380.880 343.342 459.564 1.00 57.32  ? 113 ASP A O   1 
ATOM 2232 C CB  . ASP C 3 113 ? 380.506 341.312 456.868 1.00 57.32  ? 113 ASP A CB  1 
ATOM 2233 C CG  . ASP C 3 113 ? 379.540 340.757 455.867 1.00 57.32  ? 113 ASP A CG  1 
ATOM 2234 O OD1 . ASP C 3 113 ? 378.517 340.185 456.281 1.00 57.32  ? 113 ASP A OD1 1 
ATOM 2235 O OD2 . ASP C 3 113 ? 379.797 340.890 454.657 1.00 57.32  ? 113 ASP A OD2 1 
ATOM 2236 N N   . LEU C 3 114 ? 381.744 341.293 459.623 1.00 57.54  ? 114 LEU A N   1 
ATOM 2237 C CA  . LEU C 3 114 ? 382.697 341.675 460.646 1.00 57.54  ? 114 LEU A CA  1 
ATOM 2238 C C   . LEU C 3 114 ? 384.086 341.213 460.256 1.00 57.54  ? 114 LEU A C   1 
ATOM 2239 O O   . LEU C 3 114 ? 384.263 340.139 459.685 1.00 57.54  ? 114 LEU A O   1 
ATOM 2240 C CB  . LEU C 3 114 ? 382.316 341.095 462.005 1.00 57.54  ? 114 LEU A CB  1 
ATOM 2241 C CG  . LEU C 3 114 ? 382.886 341.824 463.211 1.00 57.54  ? 114 LEU A CG  1 
ATOM 2242 C CD1 . LEU C 3 114 ? 382.678 343.296 463.033 1.00 57.54  ? 114 LEU A CD1 1 
ATOM 2243 C CD2 . LEU C 3 114 ? 382.208 341.357 464.463 1.00 57.54  ? 114 LEU A CD2 1 
ATOM 2244 N N   . GLU C 3 115 ? 385.074 342.036 460.578 1.00 60.77  ? 115 GLU A N   1 
ATOM 2245 C CA  . GLU C 3 115 ? 386.453 341.774 460.204 1.00 60.77  ? 115 GLU A CA  1 
ATOM 2246 C C   . GLU C 3 115 ? 387.335 342.188 461.365 1.00 60.77  ? 115 GLU A C   1 
ATOM 2247 O O   . GLU C 3 115 ? 387.293 343.344 461.785 1.00 60.77  ? 115 GLU A O   1 
ATOM 2248 C CB  . GLU C 3 115 ? 386.816 342.546 458.943 1.00 60.77  ? 115 GLU A CB  1 
ATOM 2249 C CG  . GLU C 3 115 ? 388.110 342.149 458.324 1.00 60.77  ? 115 GLU A CG  1 
ATOM 2250 C CD  . GLU C 3 115 ? 388.742 343.290 457.561 1.00 60.77  ? 115 GLU A CD  1 
ATOM 2251 O OE1 . GLU C 3 115 ? 389.385 344.143 458.206 1.00 60.77  ? 115 GLU A OE1 1 
ATOM 2252 O OE2 . GLU C 3 115 ? 388.603 343.343 456.321 1.00 60.77  ? 115 GLU A OE2 1 
ATOM 2253 N N   . LEU C 3 116 ? 388.120 341.258 461.888 1.00 54.93  ? 116 LEU A N   1 
ATOM 2254 C CA  . LEU C 3 116 ? 388.905 341.501 463.085 1.00 54.93  ? 116 LEU A CA  1 
ATOM 2255 C C   . LEU C 3 116 ? 390.371 341.248 462.802 1.00 54.93  ? 116 LEU A C   1 
ATOM 2256 O O   . LEU C 3 116 ? 390.714 340.320 462.076 1.00 54.93  ? 116 LEU A O   1 
ATOM 2257 C CB  . LEU C 3 116 ? 388.447 340.617 464.240 1.00 54.93  ? 116 LEU A CB  1 
ATOM 2258 C CG  . LEU C 3 116 ? 387.051 340.904 464.785 1.00 54.93  ? 116 LEU A CG  1 
ATOM 2259 C CD1 . LEU C 3 116 ? 386.093 339.897 464.254 1.00 54.93  ? 116 LEU A CD1 1 
ATOM 2260 C CD2 . LEU C 3 116 ? 387.033 340.895 466.281 1.00 54.93  ? 116 LEU A CD2 1 
ATOM 2261 N N   . THR C 3 117 ? 391.233 342.072 463.388 1.00 51.82  ? 117 THR A N   1 
ATOM 2262 C CA  . THR C 3 117 ? 392.673 341.935 463.228 1.00 51.82  ? 117 THR A CA  1 
ATOM 2263 C C   . THR C 3 117 ? 393.331 342.109 464.583 1.00 51.82  ? 117 THR A C   1 
ATOM 2264 O O   . THR C 3 117 ? 392.933 342.980 465.356 1.00 51.82  ? 117 THR A O   1 
ATOM 2265 C CB  . THR C 3 117 ? 393.222 342.959 462.242 1.00 51.82  ? 117 THR A CB  1 
ATOM 2266 O OG1 . THR C 3 117 ? 392.355 343.035 461.110 1.00 51.82  ? 117 THR A OG1 1 
ATOM 2267 C CG2 . THR C 3 117 ? 394.573 342.541 461.763 1.00 51.82  ? 117 THR A CG2 1 
ATOM 2268 N N   . PHE C 3 118 ? 394.328 341.286 464.868 1.00 49.12  ? 118 PHE A N   1 
ATOM 2269 C CA  . PHE C 3 118 ? 394.916 341.179 466.190 1.00 49.12  ? 118 PHE A CA  1 
ATOM 2270 C C   . PHE C 3 118 ? 396.381 341.570 466.125 1.00 49.12  ? 118 PHE A C   1 
ATOM 2271 O O   . PHE C 3 118 ? 397.144 340.992 465.350 1.00 49.12  ? 118 PHE A O   1 
ATOM 2272 C CB  . PHE C 3 118 ? 394.785 339.753 466.723 1.00 49.12  ? 118 PHE A CB  1 
ATOM 2273 C CG  . PHE C 3 118 ? 393.382 339.253 466.771 1.00 49.12  ? 118 PHE A CG  1 
ATOM 2274 C CD1 . PHE C 3 118 ? 392.614 339.448 467.891 1.00 49.12  ? 118 PHE A CD1 1 
ATOM 2275 C CD2 . PHE C 3 118 ? 392.835 338.579 465.705 1.00 49.12  ? 118 PHE A CD2 1 
ATOM 2276 C CE1 . PHE C 3 118 ? 391.331 339.000 467.940 1.00 49.12  ? 118 PHE A CE1 1 
ATOM 2277 C CE2 . PHE C 3 118 ? 391.552 338.131 465.751 1.00 49.12  ? 118 PHE A CE2 1 
ATOM 2278 C CZ  . PHE C 3 118 ? 390.800 338.344 466.870 1.00 49.12  ? 118 PHE A CZ  1 
ATOM 2279 N N   . VAL C 3 119 ? 396.779 342.531 466.944 1.00 48.61  ? 119 VAL A N   1 
ATOM 2280 C CA  . VAL C 3 119 ? 398.160 342.994 466.979 1.00 48.61  ? 119 VAL A CA  1 
ATOM 2281 C C   . VAL C 3 119 ? 398.747 342.469 468.282 1.00 48.61  ? 119 VAL A C   1 
ATOM 2282 O O   . VAL C 3 119 ? 398.648 343.097 469.330 1.00 48.61  ? 119 VAL A O   1 
ATOM 2283 C CB  . VAL C 3 119 ? 398.254 344.511 466.867 1.00 48.61  ? 119 VAL A CB  1 
ATOM 2284 C CG1 . VAL C 3 119 ? 399.677 344.928 466.737 1.00 48.61  ? 119 VAL A CG1 1 
ATOM 2285 C CG2 . VAL C 3 119 ? 397.479 344.987 465.674 1.00 48.61  ? 119 VAL A CG2 1 
ATOM 2286 N N   . ILE C 3 120 ? 399.374 341.299 468.214 1.00 49.55  ? 120 ILE A N   1 
ATOM 2287 C CA  . ILE C 3 120 ? 399.903 340.623 469.390 1.00 49.55  ? 120 ILE A CA  1 
ATOM 2288 C C   . ILE C 3 120 ? 401.390 340.898 469.500 1.00 49.55  ? 120 ILE A C   1 
ATOM 2289 O O   . ILE C 3 120 ? 402.142 340.683 468.546 1.00 49.55  ? 120 ILE A O   1 
ATOM 2290 C CB  . ILE C 3 120 ? 399.638 339.115 469.336 1.00 49.55  ? 120 ILE A CB  1 
ATOM 2291 C CG1 . ILE C 3 120 ? 398.173 338.853 469.047 1.00 49.55  ? 120 ILE A CG1 1 
ATOM 2292 C CG2 . ILE C 3 120 ? 400.002 338.503 470.643 1.00 49.55  ? 120 ILE A CG2 1 
ATOM 2293 C CD1 . ILE C 3 120 ? 397.817 337.410 468.975 1.00 49.55  ? 120 ILE A CD1 1 
ATOM 2294 N N   . THR C 3 121 ? 401.811 341.387 470.660 1.00 55.99  ? 121 THR A N   1 
ATOM 2295 C CA  . THR C 3 121 ? 403.205 341.652 470.959 1.00 55.99  ? 121 THR A CA  1 
ATOM 2296 C C   . THR C 3 121 ? 403.603 340.823 472.161 1.00 55.99  ? 121 THR A C   1 
ATOM 2297 O O   . THR C 3 121 ? 402.804 340.060 472.690 1.00 55.99  ? 121 THR A O   1 
ATOM 2298 C CB  . THR C 3 121 ? 403.460 343.112 471.271 1.00 55.99  ? 121 THR A CB  1 
ATOM 2299 O OG1 . THR C 3 121 ? 402.934 343.400 472.569 1.00 55.99  ? 121 THR A OG1 1 
ATOM 2300 C CG2 . THR C 3 121 ? 402.805 344.004 470.243 1.00 55.99  ? 121 THR A CG2 1 
ATOM 2301 N N   . SER C 3 122 ? 404.847 340.970 472.588 1.00 59.61  ? 122 SER A N   1 
ATOM 2302 C CA  . SER C 3 122 ? 405.374 340.174 473.680 1.00 59.61  ? 122 SER A CA  1 
ATOM 2303 C C   . SER C 3 122 ? 406.317 341.008 474.532 1.00 59.61  ? 122 SER A C   1 
ATOM 2304 O O   . SER C 3 122 ? 406.724 342.107 474.153 1.00 59.61  ? 122 SER A O   1 
ATOM 2305 C CB  . SER C 3 122 ? 406.096 338.942 473.146 1.00 59.61  ? 122 SER A CB  1 
ATOM 2306 O OG  . SER C 3 122 ? 406.225 337.969 474.151 1.00 59.61  ? 122 SER A OG  1 
ATOM 2307 N N   . ALA C 3 123 ? 406.680 340.467 475.692 1.00 64.18  ? 123 ALA A N   1 
ATOM 2308 C CA  . ALA C 3 123 ? 407.632 341.116 476.584 1.00 64.18  ? 123 ALA A CA  1 
ATOM 2309 C C   . ALA C 3 123 ? 408.246 340.068 477.490 1.00 64.18  ? 123 ALA A C   1 
ATOM 2310 O O   . ALA C 3 123 ? 407.560 339.134 477.903 1.00 64.18  ? 123 ALA A O   1 
ATOM 2311 C CB  . ALA C 3 123 ? 406.964 342.198 477.428 1.00 64.18  ? 123 ALA A CB  1 
ATOM 2312 N N   . GLN C 3 124 ? 409.523 340.228 477.807 1.00 70.39  ? 124 GLN A N   1 
ATOM 2313 C CA  . GLN C 3 124 ? 410.206 339.280 478.669 1.00 70.39  ? 124 GLN A CA  1 
ATOM 2314 C C   . GLN C 3 124 ? 410.103 339.712 480.123 1.00 70.39  ? 124 GLN A C   1 
ATOM 2315 O O   . GLN C 3 124 ? 410.648 340.746 480.513 1.00 70.39  ? 124 GLN A O   1 
ATOM 2316 C CB  . GLN C 3 124 ? 411.668 339.158 478.267 1.00 70.39  ? 124 GLN A CB  1 
ATOM 2317 C CG  . GLN C 3 124 ? 412.434 338.172 479.107 1.00 70.39  ? 124 GLN A CG  1 
ATOM 2318 C CD  . GLN C 3 124 ? 413.912 338.448 479.118 1.00 70.39  ? 124 GLN A CD  1 
ATOM 2319 O OE1 . GLN C 3 124 ? 414.413 339.238 478.326 1.00 70.39  ? 124 GLN A OE1 1 
ATOM 2320 N NE2 . GLN C 3 124 ? 414.622 337.804 480.028 1.00 70.39  ? 124 GLN A NE2 1 
ATOM 2321 N N   . GLN C 3 125 ? 409.425 338.915 480.923 1.00 73.12  ? 125 GLN A N   1 
ATOM 2322 C CA  . GLN C 3 125 ? 409.256 339.190 482.334 1.00 73.12  ? 125 GLN A CA  1 
ATOM 2323 C C   . GLN C 3 125 ? 410.541 338.875 483.093 1.00 73.12  ? 125 GLN A C   1 
ATOM 2324 O O   . GLN C 3 125 ? 411.372 338.104 482.615 1.00 73.12  ? 125 GLN A O   1 
ATOM 2325 C CB  . GLN C 3 125 ? 408.100 338.361 482.868 1.00 73.12  ? 125 GLN A CB  1 
ATOM 2326 C CG  . GLN C 3 125 ? 406.778 338.802 482.342 1.00 73.12  ? 125 GLN A CG  1 
ATOM 2327 C CD  . GLN C 3 125 ? 406.385 340.132 482.888 1.00 73.12  ? 125 GLN A CD  1 
ATOM 2328 O OE1 . GLN C 3 125 ? 406.494 341.150 482.213 1.00 73.12  ? 125 GLN A OE1 1 
ATOM 2329 N NE2 . GLN C 3 125 ? 405.931 340.142 484.129 1.00 73.12  ? 125 GLN A NE2 1 
ATOM 2330 N N   . PRO C 3 126 ? 410.745 339.477 484.278 1.00 77.01  ? 126 PRO A N   1 
ATOM 2331 C CA  . PRO C 3 126 ? 411.967 339.187 485.038 1.00 77.01  ? 126 PRO A CA  1 
ATOM 2332 C C   . PRO C 3 126 ? 412.018 337.781 485.605 1.00 77.01  ? 126 PRO A C   1 
ATOM 2333 O O   . PRO C 3 126 ? 411.282 337.450 486.537 1.00 77.01  ? 126 PRO A O   1 
ATOM 2334 C CB  . PRO C 3 126 ? 411.935 340.228 486.162 1.00 77.01  ? 126 PRO A CB  1 
ATOM 2335 C CG  . PRO C 3 126 ? 410.524 340.663 486.239 1.00 77.01  ? 126 PRO A CG  1 
ATOM 2336 C CD  . PRO C 3 126 ? 410.039 340.638 484.843 1.00 77.01  ? 126 PRO A CD  1 
ATOM 2337 N N   . SER C 3 127 ? 412.890 336.951 485.042 1.00 86.47  ? 127 SER A N   1 
ATOM 2338 C CA  . SER C 3 127 ? 413.103 335.593 485.522 1.00 86.47  ? 127 SER A CA  1 
ATOM 2339 C C   . SER C 3 127 ? 414.247 335.586 486.527 1.00 86.47  ? 127 SER A C   1 
ATOM 2340 O O   . SER C 3 127 ? 414.706 336.634 486.985 1.00 86.47  ? 127 SER A O   1 
ATOM 2341 C CB  . SER C 3 127 ? 413.382 334.650 484.361 1.00 86.47  ? 127 SER A CB  1 
ATOM 2342 O OG  . SER C 3 127 ? 413.710 333.363 484.840 1.00 86.47  ? 127 SER A OG  1 
ATOM 2343 N N   . THR C 3 128 ? 414.736 334.397 486.875 1.00 92.95  ? 128 THR A N   1 
ATOM 2344 C CA  . THR C 3 128 ? 415.762 334.315 487.912 1.00 92.95  ? 128 THR A CA  1 
ATOM 2345 C C   . THR C 3 128 ? 417.145 334.630 487.358 1.00 92.95  ? 128 THR A C   1 
ATOM 2346 O O   . THR C 3 128 ? 417.693 335.704 487.628 1.00 92.95  ? 128 THR A O   1 
ATOM 2347 C CB  . THR C 3 128 ? 415.756 332.925 488.544 1.00 92.95  ? 128 THR A CB  1 
ATOM 2348 O OG1 . THR C 3 128 ? 416.402 332.005 487.654 1.00 92.95  ? 128 THR A OG1 1 
ATOM 2349 C CG2 . THR C 3 128 ? 414.332 332.471 488.798 1.00 92.95  ? 128 THR A CG2 1 
ATOM 2350 N N   . ALA C 3 129 ? 417.682 333.746 486.515 1.00 96.30  ? 129 ALA A N   1 
ATOM 2351 C CA  . ALA C 3 129 ? 419.066 333.845 486.040 1.00 96.30  ? 129 ALA A CA  1 
ATOM 2352 C C   . ALA C 3 129 ? 419.310 332.807 484.949 1.00 96.30  ? 129 ALA A C   1 
ATOM 2353 O O   . ALA C 3 129 ? 418.398 332.084 484.530 1.00 96.30  ? 129 ALA A O   1 
ATOM 2354 C CB  . ALA C 3 129 ? 420.078 333.646 487.174 1.00 96.30  ? 129 ALA A CB  1 
ATOM 2355 N N   . SER C 3 130 ? 420.578 332.729 484.530 1.00 97.99  ? 130 SER A N   1 
ATOM 2356 C CA  . SER C 3 130 ? 421.186 331.661 483.724 1.00 97.99  ? 130 SER A CA  1 
ATOM 2357 C C   . SER C 3 130 ? 420.523 331.491 482.356 1.00 97.99  ? 130 SER A C   1 
ATOM 2358 O O   . SER C 3 130 ? 419.913 330.463 482.061 1.00 97.99  ? 130 SER A O   1 
ATOM 2359 C CB  . SER C 3 130 ? 421.232 330.321 484.474 1.00 97.99  ? 130 SER A CB  1 
ATOM 2360 O OG  . SER C 3 130 ? 419.984 329.898 484.996 1.00 97.99  ? 130 SER A OG  1 
ATOM 2361 N N   . SER C 3 131 ? 420.669 332.529 481.529 1.00 93.93  ? 131 SER A N   1 
ATOM 2362 C CA  . SER C 3 131 ? 420.613 332.444 480.065 1.00 93.93  ? 131 SER A CA  1 
ATOM 2363 C C   . SER C 3 131 ? 419.254 331.960 479.552 1.00 93.93  ? 131 SER A C   1 
ATOM 2364 O O   . SER C 3 131 ? 419.112 330.866 479.012 1.00 93.93  ? 131 SER A O   1 
ATOM 2365 C CB  . SER C 3 131 ? 421.730 331.539 479.537 1.00 93.93  ? 131 SER A CB  1 
ATOM 2366 O OG  . SER C 3 131 ? 421.405 331.051 478.250 1.00 93.93  ? 131 SER A OG  1 
ATOM 2367 N N   . VAL C 3 132 ? 418.253 332.808 479.758 1.00 88.75  ? 132 VAL A N   1 
ATOM 2368 C CA  . VAL C 3 132 ? 416.946 332.570 479.167 1.00 88.75  ? 132 VAL A CA  1 
ATOM 2369 C C   . VAL C 3 132 ? 417.043 332.703 477.655 1.00 88.75  ? 132 VAL A C   1 
ATOM 2370 O O   . VAL C 3 132 ? 417.343 333.779 477.125 1.00 88.75  ? 132 VAL A O   1 
ATOM 2371 C CB  . VAL C 3 132 ? 415.913 333.547 479.740 1.00 88.75  ? 132 VAL A CB  1 
ATOM 2372 C CG1 . VAL C 3 132 ? 414.619 333.462 478.961 1.00 88.75  ? 132 VAL A CG1 1 
ATOM 2373 C CG2 . VAL C 3 132 ? 415.677 333.257 481.207 1.00 88.75  ? 132 VAL A CG2 1 
ATOM 2374 N N   . ASP C 3 133 ? 416.802 331.603 476.952 1.00 88.41  ? 133 ASP A N   1 
ATOM 2375 C CA  . ASP C 3 133 ? 416.722 331.612 475.500 1.00 88.41  ? 133 ASP A CA  1 
ATOM 2376 C C   . ASP C 3 133 ? 415.374 331.039 475.101 1.00 88.41  ? 133 ASP A C   1 
ATOM 2377 O O   . ASP C 3 133 ? 414.948 330.018 475.644 1.00 88.41  ? 133 ASP A O   1 
ATOM 2378 C CB  . ASP C 3 133 ? 417.866 330.811 474.874 1.00 88.41  ? 133 ASP A CB  1 
ATOM 2379 C CG  . ASP C 3 133 ? 417.704 330.626 473.379 1.00 88.41  ? 133 ASP A CG  1 
ATOM 2380 O OD1 . ASP C 3 133 ? 417.005 329.682 472.951 1.00 88.41  ? 133 ASP A OD1 1 
ATOM 2381 O OD2 . ASP C 3 133 ? 418.331 331.394 472.623 1.00 88.41  ? 133 ASP A OD2 1 
ATOM 2382 N N   . ALA C 3 134 ? 414.713 331.688 474.155 1.00 78.42  ? 134 ALA A N   1 
ATOM 2383 C CA  . ALA C 3 134 ? 413.349 331.324 473.834 1.00 78.42  ? 134 ALA A CA  1 
ATOM 2384 C C   . ALA C 3 134 ? 413.185 331.116 472.339 1.00 78.42  ? 134 ALA A C   1 
ATOM 2385 O O   . ALA C 3 134 ? 413.760 331.853 471.535 1.00 78.42  ? 134 ALA A O   1 
ATOM 2386 C CB  . ALA C 3 134 ? 412.373 332.407 474.304 1.00 78.42  ? 134 ALA A CB  1 
ATOM 2387 N N   . PRO C 3 135 ? 412.408 330.120 471.941 1.00 69.43  ? 135 PRO A N   1 
ATOM 2388 C CA  . PRO C 3 135 ? 412.032 329.998 470.531 1.00 69.43  ? 135 PRO A CA  1 
ATOM 2389 C C   . PRO C 3 135 ? 410.921 330.964 470.175 1.00 69.43  ? 135 PRO A C   1 
ATOM 2390 O O   . PRO C 3 135 ? 410.459 331.712 471.037 1.00 69.43  ? 135 PRO A O   1 
ATOM 2391 C CB  . PRO C 3 135 ? 411.566 328.543 470.419 1.00 69.43  ? 135 PRO A CB  1 
ATOM 2392 C CG  . PRO C 3 135 ? 412.053 327.876 471.662 1.00 69.43  ? 135 PRO A CG  1 
ATOM 2393 C CD  . PRO C 3 135 ? 412.038 328.923 472.704 1.00 69.43  ? 135 PRO A CD  1 
ATOM 2394 N N   . VAL C 3 136 ? 410.475 330.961 468.922 1.00 63.12  ? 136 VAL A N   1 
ATOM 2395 C CA  . VAL C 3 136 ? 409.384 331.841 468.528 1.00 63.12  ? 136 VAL A CA  1 
ATOM 2396 C C   . VAL C 3 136 ? 408.081 331.332 469.119 1.00 63.12  ? 136 VAL A C   1 
ATOM 2397 O O   . VAL C 3 136 ? 407.820 330.124 469.149 1.00 63.12  ? 136 VAL A O   1 
ATOM 2398 C CB  . VAL C 3 136 ? 409.302 331.950 466.999 1.00 63.12  ? 136 VAL A CB  1 
ATOM 2399 C CG1 . VAL C 3 136 ? 410.336 332.919 466.493 1.00 63.12  ? 136 VAL A CG1 1 
ATOM 2400 C CG2 . VAL C 3 136 ? 409.536 330.599 466.373 1.00 63.12  ? 136 VAL A CG2 1 
ATOM 2401 N N   . GLN C 3 137 ? 407.262 332.254 469.604 1.00 58.15  ? 137 GLN A N   1 
ATOM 2402 C CA  . GLN C 3 137 ? 406.052 331.911 470.326 1.00 58.15  ? 137 GLN A CA  1 
ATOM 2403 C C   . GLN C 3 137 ? 404.869 331.772 469.381 1.00 58.15  ? 137 GLN A C   1 
ATOM 2404 O O   . GLN C 3 137 ? 404.827 332.357 468.301 1.00 58.15  ? 137 GLN A O   1 
ATOM 2405 C CB  . GLN C 3 137 ? 405.758 332.964 471.378 1.00 58.15  ? 137 GLN A CB  1 
ATOM 2406 C CG  . GLN C 3 137 ? 406.888 333.180 472.319 1.00 58.15  ? 137 GLN A CG  1 
ATOM 2407 C CD  . GLN C 3 137 ? 407.094 332.004 473.212 1.00 58.15  ? 137 GLN A CD  1 
ATOM 2408 O OE1 . GLN C 3 137 ? 408.182 331.442 473.278 1.00 58.15  ? 137 GLN A OE1 1 
ATOM 2409 N NE2 . GLN C 3 137 ? 406.046 331.616 473.916 1.00 58.15  ? 137 GLN A NE2 1 
ATOM 2410 N N   . THR C 3 138 ? 403.886 330.992 469.816 1.00 54.29  ? 138 THR A N   1 
ATOM 2411 C CA  . THR C 3 138 ? 402.687 330.734 469.040 1.00 54.29  ? 138 THR A CA  1 
ATOM 2412 C C   . THR C 3 138 ? 401.494 330.945 469.950 1.00 54.29  ? 138 THR A C   1 
ATOM 2413 O O   . THR C 3 138 ? 401.532 330.537 471.112 1.00 54.29  ? 138 THR A O   1 
ATOM 2414 C CB  . THR C 3 138 ? 402.687 329.310 468.484 1.00 54.29  ? 138 THR A CB  1 
ATOM 2415 O OG1 . THR C 3 138 ? 403.935 329.052 467.839 1.00 54.29  ? 138 THR A OG1 1 
ATOM 2416 C CG2 . THR C 3 138 ? 401.581 329.113 467.483 1.00 54.29  ? 138 THR A CG2 1 
ATOM 2417 N N   . HIS C 3 139 ? 400.452 331.586 469.431 1.00 50.56  ? 139 HIS A N   1 
ATOM 2418 C CA  . HIS C 3 139 ? 399.255 331.899 470.189 1.00 50.56  ? 139 HIS A CA  1 
ATOM 2419 C C   . HIS C 3 139 ? 398.043 331.284 469.512 1.00 50.56  ? 139 HIS A C   1 
ATOM 2420 O O   . HIS C 3 139 ? 398.077 330.964 468.327 1.00 50.56  ? 139 HIS A O   1 
ATOM 2421 C CB  . HIS C 3 139 ? 399.058 333.401 470.315 1.00 50.56  ? 139 HIS A CB  1 
ATOM 2422 C CG  . HIS C 3 139 ? 400.295 334.151 470.692 1.00 50.56  ? 139 HIS A CG  1 
ATOM 2423 N ND1 . HIS C 3 139 ? 400.533 334.592 471.972 1.00 50.56  ? 139 HIS A ND1 1 
ATOM 2424 C CD2 . HIS C 3 139 ? 401.347 334.566 469.951 1.00 50.56  ? 139 HIS A CD2 1 
ATOM 2425 C CE1 . HIS C 3 139 ? 401.688 335.229 472.008 1.00 50.56  ? 139 HIS A CE1 1 
ATOM 2426 N NE2 . HIS C 3 139 ? 402.202 335.226 470.795 1.00 50.56  ? 139 HIS A NE2 1 
ATOM 2427 N N   . GLN C 3 140 ? 396.967 331.119 470.273 1.00 47.36  ? 140 GLN A N   1 
ATOM 2428 C CA  . GLN C 3 140 ? 395.713 330.589 469.758 1.00 47.36  ? 140 GLN A CA  1 
ATOM 2429 C C   . GLN C 3 140 ? 394.606 331.586 470.042 1.00 47.36  ? 140 GLN A C   1 
ATOM 2430 O O   . GLN C 3 140 ? 394.474 332.053 471.172 1.00 47.36  ? 140 GLN A O   1 
ATOM 2431 C CB  . GLN C 3 140 ? 395.374 329.243 470.388 1.00 47.36  ? 140 GLN A CB  1 
ATOM 2432 C CG  . GLN C 3 140 ? 394.040 328.727 469.937 1.00 47.36  ? 140 GLN A CG  1 
ATOM 2433 C CD  . GLN C 3 140 ? 393.702 327.400 470.498 1.00 47.36  ? 140 GLN A CD  1 
ATOM 2434 O OE1 . GLN C 3 140 ? 394.372 326.904 471.388 1.00 47.36  ? 140 GLN A OE1 1 
ATOM 2435 N NE2 . GLN C 3 140 ? 392.653 326.802 469.980 1.00 47.36  ? 140 GLN A NE2 1 
ATOM 2436 N N   . ILE C 3 141 ? 393.814 331.902 469.030 1.00 47.56  ? 141 ILE A N   1 
ATOM 2437 C CA  . ILE C 3 141 ? 392.729 332.873 469.140 1.00 47.56  ? 141 ILE A CA  1 
ATOM 2438 C C   . ILE C 3 141 ? 391.441 332.130 468.813 1.00 47.56  ? 141 ILE A C   1 
ATOM 2439 O O   . ILE C 3 141 ? 391.094 331.946 467.648 1.00 47.56  ? 141 ILE A O   1 
ATOM 2440 C CB  . ILE C 3 141 ? 392.933 334.069 468.213 1.00 47.56  ? 141 ILE A CB  1 
ATOM 2441 C CG1 . ILE C 3 141 ? 394.274 334.725 468.496 1.00 47.56  ? 141 ILE A CG1 1 
ATOM 2442 C CG2 . ILE C 3 141 ? 391.843 335.065 468.403 1.00 47.56  ? 141 ILE A CG2 1 
ATOM 2443 C CD1 . ILE C 3 141 ? 395.025 335.103 467.278 1.00 47.56  ? 141 ILE A CD1 1 
ATOM 2444 N N   . MET C 3 142 ? 390.714 331.697 469.833 1.00 50.94  ? 142 MET A N   1 
ATOM 2445 C CA  . MET C 3 142 ? 389.526 330.889 469.611 1.00 50.94  ? 142 MET A CA  1 
ATOM 2446 C C   . MET C 3 142 ? 388.280 331.748 469.604 1.00 50.94  ? 142 MET A C   1 
ATOM 2447 O O   . MET C 3 142 ? 388.112 332.628 470.444 1.00 50.94  ? 142 MET A O   1 
ATOM 2448 C CB  . MET C 3 142 ? 389.386 329.818 470.684 1.00 50.94  ? 142 MET A CB  1 
ATOM 2449 C CG  . MET C 3 142 ? 388.504 328.679 470.259 1.00 50.94  ? 142 MET A CG  1 
ATOM 2450 S SD  . MET C 3 142 ? 388.115 327.562 471.594 1.00 50.94  ? 142 MET A SD  1 
ATOM 2451 C CE  . MET C 3 142 ? 387.638 328.736 472.829 1.00 50.94  ? 142 MET A CE  1 
ATOM 2452 N N   . TYR C 3 143 ? 387.388 331.470 468.664 1.00 51.54  ? 143 TYR A N   1 
ATOM 2453 C CA  . TYR C 3 143 ? 386.146 332.213 468.525 1.00 51.54  ? 143 TYR A CA  1 
ATOM 2454 C C   . TYR C 3 143 ? 384.984 331.301 468.865 1.00 51.54  ? 143 TYR A C   1 
ATOM 2455 O O   . TYR C 3 143 ? 384.754 330.307 468.175 1.00 51.54  ? 143 TYR A O   1 
ATOM 2456 C CB  . TYR C 3 143 ? 385.990 332.761 467.113 1.00 51.54  ? 143 TYR A CB  1 
ATOM 2457 C CG  . TYR C 3 143 ? 384.600 333.236 466.801 1.00 51.54  ? 143 TYR A CG  1 
ATOM 2458 C CD1 . TYR C 3 143 ? 384.047 334.300 467.475 1.00 51.54  ? 143 TYR A CD1 1 
ATOM 2459 C CD2 . TYR C 3 143 ? 383.846 332.624 465.825 1.00 51.54  ? 143 TYR A CD2 1 
ATOM 2460 C CE1 . TYR C 3 143 ? 382.786 334.734 467.190 1.00 51.54  ? 143 TYR A CE1 1 
ATOM 2461 C CE2 . TYR C 3 143 ? 382.582 333.056 465.536 1.00 51.54  ? 143 TYR A CE2 1 
ATOM 2462 C CZ  . TYR C 3 143 ? 382.061 334.108 466.221 1.00 51.54  ? 143 TYR A CZ  1 
ATOM 2463 O OH  . TYR C 3 143 ? 380.798 334.538 465.934 1.00 51.54  ? 143 TYR A OH  1 
ATOM 2464 N N   . VAL C 3 144 ? 384.244 331.649 469.906 1.00 52.42  ? 144 VAL A N   1 
ATOM 2465 C CA  . VAL C 3 144 ? 383.102 330.870 470.369 1.00 52.42  ? 144 VAL A CA  1 
ATOM 2466 C C   . VAL C 3 144 ? 381.842 331.460 469.749 1.00 52.42  ? 144 VAL A C   1 
ATOM 2467 O O   . VAL C 3 144 ? 381.534 332.627 470.010 1.00 52.42  ? 144 VAL A O   1 
ATOM 2468 C CB  . VAL C 3 144 ? 383.012 330.889 471.896 1.00 52.42  ? 144 VAL A CB  1 
ATOM 2469 C CG1 . VAL C 3 144 ? 381.754 330.228 472.342 1.00 52.42  ? 144 VAL A CG1 1 
ATOM 2470 C CG2 . VAL C 3 144 ? 384.189 330.203 472.485 1.00 52.42  ? 144 VAL A CG2 1 
ATOM 2471 N N   . PRO C 3 145 ? 381.097 330.712 468.943 1.00 52.98  ? 145 PRO A N   1 
ATOM 2472 C CA  . PRO C 3 145 ? 379.849 331.221 468.385 1.00 52.98  ? 145 PRO A CA  1 
ATOM 2473 C C   . PRO C 3 145 ? 378.795 331.373 469.464 1.00 52.98  ? 145 PRO A C   1 
ATOM 2474 O O   . PRO C 3 145 ? 378.974 330.858 470.576 1.00 52.98  ? 145 PRO A O   1 
ATOM 2475 C CB  . PRO C 3 145 ? 379.458 330.136 467.376 1.00 52.98  ? 145 PRO A CB  1 
ATOM 2476 C CG  . PRO C 3 145 ? 380.700 329.492 467.037 1.00 52.98  ? 145 PRO A CG  1 
ATOM 2477 C CD  . PRO C 3 145 ? 381.498 329.470 468.282 1.00 52.98  ? 145 PRO A CD  1 
ATOM 2478 N N   . PRO C 3 146 ? 377.699 332.100 469.195 1.00 55.14  ? 146 PRO A N   1 
ATOM 2479 C CA  . PRO C 3 146 ? 376.648 332.246 470.205 1.00 55.14  ? 146 PRO A CA  1 
ATOM 2480 C C   . PRO C 3 146 ? 375.958 330.942 470.547 1.00 55.14  ? 146 PRO A C   1 
ATOM 2481 O O   . PRO C 3 146 ? 375.245 330.364 469.726 1.00 55.14  ? 146 PRO A O   1 
ATOM 2482 C CB  . PRO C 3 146 ? 375.676 333.230 469.551 1.00 55.14  ? 146 PRO A CB  1 
ATOM 2483 C CG  . PRO C 3 146 ? 376.036 333.246 468.134 1.00 55.14  ? 146 PRO A CG  1 
ATOM 2484 C CD  . PRO C 3 146 ? 377.490 333.052 468.101 1.00 55.14  ? 146 PRO A CD  1 
ATOM 2485 N N   . GLY C 3 147 ? 376.175 330.480 471.772 1.00 57.72  ? 147 GLY A N   1 
ATOM 2486 C CA  . GLY C 3 147 ? 375.644 329.214 472.219 1.00 57.72  ? 147 GLY A CA  1 
ATOM 2487 C C   . GLY C 3 147 ? 376.658 328.097 472.124 1.00 57.72  ? 147 GLY A C   1 
ATOM 2488 O O   . GLY C 3 147 ? 376.305 326.961 471.812 1.00 57.72  ? 147 GLY A O   1 
ATOM 2489 N N   . GLY C 3 148 ? 377.917 328.399 472.406 1.00 58.64  ? 148 GLY A N   1 
ATOM 2490 C CA  . GLY C 3 148 ? 378.958 327.407 472.356 1.00 58.64  ? 148 GLY A CA  1 
ATOM 2491 C C   . GLY C 3 148 ? 379.602 327.208 473.709 1.00 58.64  ? 148 GLY A C   1 
ATOM 2492 O O   . GLY C 3 148 ? 379.366 327.973 474.648 1.00 58.64  ? 148 GLY A O   1 
ATOM 2493 N N   . PRO C 3 149 ? 380.409 326.162 473.846 1.00 56.88  ? 149 PRO A N   1 
ATOM 2494 C CA  . PRO C 3 149 ? 381.105 325.929 475.111 1.00 56.88  ? 149 PRO A CA  1 
ATOM 2495 C C   . PRO C 3 149 ? 382.232 326.917 475.328 1.00 56.88  ? 149 PRO A C   1 
ATOM 2496 O O   . PRO C 3 149 ? 382.917 327.339 474.398 1.00 56.88  ? 149 PRO A O   1 
ATOM 2497 C CB  . PRO C 3 149 ? 381.641 324.505 474.960 1.00 56.88  ? 149 PRO A CB  1 
ATOM 2498 C CG  . PRO C 3 149 ? 381.691 324.278 473.519 1.00 56.88  ? 149 PRO A CG  1 
ATOM 2499 C CD  . PRO C 3 149 ? 380.552 325.023 472.931 1.00 56.88  ? 149 PRO A CD  1 
ATOM 2500 N N   . VAL C 3 150 ? 382.420 327.269 476.592 1.00 58.25  ? 150 VAL A N   1 
ATOM 2501 C CA  . VAL C 3 150 ? 383.239 328.398 477.013 1.00 58.25  ? 150 VAL A CA  1 
ATOM 2502 C C   . VAL C 3 150 ? 384.344 327.912 477.940 1.00 58.25  ? 150 VAL A C   1 
ATOM 2503 O O   . VAL C 3 150 ? 384.058 327.193 478.905 1.00 58.25  ? 150 VAL A O   1 
ATOM 2504 C CB  . VAL C 3 150 ? 382.360 329.452 477.698 1.00 58.25  ? 150 VAL A CB  1 
ATOM 2505 C CG1 . VAL C 3 150 ? 383.181 330.409 478.481 1.00 58.25  ? 150 VAL A CG1 1 
ATOM 2506 C CG2 . VAL C 3 150 ? 381.566 330.203 476.669 1.00 58.25  ? 150 VAL A CG2 1 
ATOM 2507 N N   . PRO C 3 151 ? 385.600 328.261 477.691 1.00 59.26  ? 151 PRO A N   1 
ATOM 2508 C CA  . PRO C 3 151 ? 386.673 327.874 478.603 1.00 59.26  ? 151 PRO A CA  1 
ATOM 2509 C C   . PRO C 3 151 ? 386.624 328.663 479.896 1.00 59.26  ? 151 PRO A C   1 
ATOM 2510 O O   . PRO C 3 151 ? 386.117 329.780 479.963 1.00 59.26  ? 151 PRO A O   1 
ATOM 2511 C CB  . PRO C 3 151 ? 387.944 328.215 477.825 1.00 59.26  ? 151 PRO A CB  1 
ATOM 2512 C CG  . PRO C 3 151 ? 387.515 328.483 476.475 1.00 59.26  ? 151 PRO A CG  1 
ATOM 2513 C CD  . PRO C 3 151 ? 386.129 328.968 476.526 1.00 59.26  ? 151 PRO A CD  1 
ATOM 2514 N N   . THR C 3 152 ? 387.177 328.055 480.932 1.00 64.65  ? 152 THR A N   1 
ATOM 2515 C CA  . THR C 3 152 ? 387.314 328.707 482.219 1.00 64.65  ? 152 THR A CA  1 
ATOM 2516 C C   . THR C 3 152 ? 388.689 328.550 482.831 1.00 64.65  ? 152 THR A C   1 
ATOM 2517 O O   . THR C 3 152 ? 388.961 329.189 483.851 1.00 64.65  ? 152 THR A O   1 
ATOM 2518 C CB  . THR C 3 152 ? 386.274 328.174 483.204 1.00 64.65  ? 152 THR A CB  1 
ATOM 2519 O OG1 . THR C 3 152 ? 386.488 328.774 484.483 1.00 64.65  ? 152 THR A OG1 1 
ATOM 2520 C CG2 . THR C 3 152 ? 386.400 326.679 483.330 1.00 64.65  ? 152 THR A CG2 1 
ATOM 2521 N N   . LYS C 3 153 ? 389.555 327.723 482.263 1.00 65.61  ? 153 LYS A N   1 
ATOM 2522 C CA  . LYS C 3 153 ? 390.936 327.597 482.682 1.00 65.61  ? 153 LYS A CA  1 
ATOM 2523 C C   . LYS C 3 153 ? 391.814 327.572 481.444 1.00 65.61  ? 153 LYS A C   1 
ATOM 2524 O O   . LYS C 3 153 ? 391.330 327.556 480.312 1.00 65.61  ? 153 LYS A O   1 
ATOM 2525 C CB  . LYS C 3 153 ? 391.156 326.335 483.513 1.00 65.61  ? 153 LYS A CB  1 
ATOM 2526 C CG  . LYS C 3 153 ? 390.531 326.363 484.880 1.00 65.61  ? 153 LYS A CG  1 
ATOM 2527 C CD  . LYS C 3 153 ? 390.341 324.959 485.394 1.00 65.61  ? 153 LYS A CD  1 
ATOM 2528 C CE  . LYS C 3 153 ? 389.346 324.225 484.530 1.00 65.61  ? 153 LYS A CE  1 
ATOM 2529 N NZ  . LYS C 3 153 ? 389.162 322.819 484.953 1.00 65.61  ? 153 LYS A NZ  1 
ATOM 2530 N N   . VAL C 3 154 ? 393.124 327.556 481.661 1.00 64.53  ? 154 VAL A N   1 
ATOM 2531 C CA  . VAL C 3 154 ? 394.057 327.533 480.544 1.00 64.53  ? 154 VAL A CA  1 
ATOM 2532 C C   . VAL C 3 154 ? 394.174 326.116 479.994 1.00 64.53  ? 154 VAL A C   1 
ATOM 2533 O O   . VAL C 3 154 ? 394.383 325.903 478.795 1.00 64.53  ? 154 VAL A O   1 
ATOM 2534 C CB  . VAL C 3 154 ? 395.415 328.094 480.988 1.00 64.53  ? 154 VAL A CB  1 
ATOM 2535 C CG1 . VAL C 3 154 ? 396.361 328.220 479.825 1.00 64.53  ? 154 VAL A CG1 1 
ATOM 2536 C CG2 . VAL C 3 154 ? 395.217 329.422 481.657 1.00 64.53  ? 154 VAL A CG2 1 
ATOM 2537 N N   . LYS C 3 155 ? 394.020 325.122 480.862 1.00 67.75  ? 155 LYS A N   1 
ATOM 2538 C CA  . LYS C 3 155 ? 393.983 323.722 480.448 1.00 67.75  ? 155 LYS A CA  1 
ATOM 2539 C C   . LYS C 3 155 ? 392.550 323.231 480.589 1.00 67.75  ? 155 LYS A C   1 
ATOM 2540 O O   . LYS C 3 155 ? 392.163 322.706 481.632 1.00 67.75  ? 155 LYS A O   1 
ATOM 2541 C CB  . LYS C 3 155 ? 394.942 322.885 481.284 1.00 67.75  ? 155 LYS A CB  1 
ATOM 2542 C CG  . LYS C 3 155 ? 396.253 322.550 480.594 1.00 67.75  ? 155 LYS A CG  1 
ATOM 2543 C CD  . LYS C 3 155 ? 397.283 323.645 480.799 1.00 67.75  ? 155 LYS A CD  1 
ATOM 2544 C CE  . LYS C 3 155 ? 398.489 323.453 479.897 1.00 67.75  ? 155 LYS A CE  1 
ATOM 2545 N NZ  . LYS C 3 155 ? 399.456 324.576 480.020 1.00 67.75  ? 155 LYS A NZ  1 
ATOM 2546 N N   . ASP C 3 156 ? 391.761 323.388 479.531 1.00 68.02  ? 156 ASP A N   1 
ATOM 2547 C CA  . ASP C 3 156 ? 390.351 323.036 479.573 1.00 68.02  ? 156 ASP A CA  1 
ATOM 2548 C C   . ASP C 3 156 ? 389.989 322.292 478.302 1.00 68.02  ? 156 ASP A C   1 
ATOM 2549 O O   . ASP C 3 156 ? 390.731 322.306 477.321 1.00 68.02  ? 156 ASP A O   1 
ATOM 2550 C CB  . ASP C 3 156 ? 389.472 324.274 479.732 1.00 68.02  ? 156 ASP A CB  1 
ATOM 2551 C CG  . ASP C 3 156 ? 388.170 323.973 480.418 1.00 68.02  ? 156 ASP A CG  1 
ATOM 2552 O OD1 . ASP C 3 156 ? 388.203 323.343 481.490 1.00 68.02  ? 156 ASP A OD1 1 
ATOM 2553 O OD2 . ASP C 3 156 ? 387.113 324.375 479.897 1.00 68.02  ? 156 ASP A OD2 1 
ATOM 2554 N N   . TYR C 3 157 ? 388.839 321.627 478.331 1.00 69.60  ? 157 TYR A N   1 
ATOM 2555 C CA  . TYR C 3 157 ? 388.415 320.863 477.169 1.00 69.60  ? 157 TYR A CA  1 
ATOM 2556 C C   . TYR C 3 157 ? 387.908 321.773 476.065 1.00 69.60  ? 157 TYR A C   1 
ATOM 2557 O O   . TYR C 3 157 ? 388.078 321.463 474.884 1.00 69.60  ? 157 TYR A O   1 
ATOM 2558 C CB  . TYR C 3 157 ? 387.345 319.846 477.575 1.00 69.60  ? 157 TYR A CB  1 
ATOM 2559 C CG  . TYR C 3 157 ? 386.402 319.444 476.462 1.00 69.60  ? 157 TYR A CG  1 
ATOM 2560 C CD1 . TYR C 3 157 ? 386.830 318.641 475.409 1.00 69.60  ? 157 TYR A CD1 1 
ATOM 2561 C CD2 . TYR C 3 157 ? 385.079 319.874 476.465 1.00 69.60  ? 157 TYR A CD2 1 
ATOM 2562 C CE1 . TYR C 3 157 ? 385.971 318.293 474.382 1.00 69.60  ? 157 TYR A CE1 1 
ATOM 2563 C CE2 . TYR C 3 157 ? 384.209 319.525 475.446 1.00 69.60  ? 157 TYR A CE2 1 
ATOM 2564 C CZ  . TYR C 3 157 ? 384.660 318.734 474.409 1.00 69.60  ? 157 TYR A CZ  1 
ATOM 2565 O OH  . TYR C 3 157 ? 383.796 318.384 473.398 1.00 69.60  ? 157 TYR A OH  1 
ATOM 2566 N N   . ALA C 3 158 ? 387.333 322.920 476.420 1.00 60.74  ? 158 ALA A N   1 
ATOM 2567 C CA  . ALA C 3 158 ? 386.626 323.731 475.440 1.00 60.74  ? 158 ALA A CA  1 
ATOM 2568 C C   . ALA C 3 158 ? 387.552 324.448 474.474 1.00 60.74  ? 158 ALA A C   1 
ATOM 2569 O O   . ALA C 3 158 ? 387.068 325.073 473.533 1.00 60.74  ? 158 ALA A O   1 
ATOM 2570 C CB  . ALA C 3 158 ? 385.744 324.749 476.146 1.00 60.74  ? 158 ALA A CB  1 
ATOM 2571 N N   . TRP C 3 159 ? 388.863 324.393 474.687 1.00 55.86  ? 159 TRP A N   1 
ATOM 2572 C CA  . TRP C 3 159 ? 389.788 324.871 473.674 1.00 55.86  ? 159 TRP A CA  1 
ATOM 2573 C C   . TRP C 3 159 ? 389.854 323.914 472.499 1.00 55.86  ? 159 TRP A C   1 
ATOM 2574 O O   . TRP C 3 159 ? 390.119 324.331 471.370 1.00 55.86  ? 159 TRP A O   1 
ATOM 2575 C CB  . TRP C 3 159 ? 391.177 325.044 474.269 1.00 55.86  ? 159 TRP A CB  1 
ATOM 2576 C CG  . TRP C 3 159 ? 391.247 326.054 475.319 1.00 55.86  ? 159 TRP A CG  1 
ATOM 2577 C CD1 . TRP C 3 159 ? 391.151 325.851 476.652 1.00 55.86  ? 159 TRP A CD1 1 
ATOM 2578 C CD2 . TRP C 3 159 ? 391.430 327.452 475.137 1.00 55.86  ? 159 TRP A CD2 1 
ATOM 2579 N NE1 . TRP C 3 159 ? 391.262 327.037 477.322 1.00 55.86  ? 159 TRP A NE1 1 
ATOM 2580 C CE2 . TRP C 3 159 ? 391.433 328.039 476.406 1.00 55.86  ? 159 TRP A CE2 1 
ATOM 2581 C CE3 . TRP C 3 159 ? 391.592 328.267 474.017 1.00 55.86  ? 159 TRP A CE3 1 
ATOM 2582 C CZ2 . TRP C 3 159 ? 391.595 329.395 476.588 1.00 55.86  ? 159 TRP A CZ2 1 
ATOM 2583 C CZ3 . TRP C 3 159 ? 391.749 329.599 474.200 1.00 55.86  ? 159 TRP A CZ3 1 
ATOM 2584 C CH2 . TRP C 3 159 ? 391.752 330.157 475.473 1.00 55.86  ? 159 TRP A CH2 1 
ATOM 2585 N N   . GLN C 3 160 ? 389.621 322.625 472.750 1.00 62.23  ? 160 GLN A N   1 
ATOM 2586 C CA  . GLN C 3 160 ? 389.838 321.569 471.771 1.00 62.23  ? 160 GLN A CA  1 
ATOM 2587 C C   . GLN C 3 160 ? 388.577 321.175 471.031 1.00 62.23  ? 160 GLN A C   1 
ATOM 2588 O O   . GLN C 3 160 ? 388.599 320.184 470.294 1.00 62.23  ? 160 GLN A O   1 
ATOM 2589 C CB  . GLN C 3 160 ? 390.436 320.339 472.449 1.00 62.23  ? 160 GLN A CB  1 
ATOM 2590 C CG  . GLN C 3 160 ? 391.927 320.371 472.549 1.00 62.23  ? 160 GLN A CG  1 
ATOM 2591 C CD  . GLN C 3 160 ? 392.396 320.950 473.852 1.00 62.23  ? 160 GLN A CD  1 
ATOM 2592 O OE1 . GLN C 3 160 ? 391.591 321.330 474.691 1.00 62.23  ? 160 GLN A OE1 1 
ATOM 2593 N NE2 . GLN C 3 160 ? 393.706 321.033 474.030 1.00 62.23  ? 160 GLN A NE2 1 
ATOM 2594 N N   . THR C 3 161 ? 387.481 321.910 471.201 1.00 61.04  ? 161 THR A N   1 
ATOM 2595 C CA  . THR C 3 161 ? 386.240 321.530 470.549 1.00 61.04  ? 161 THR A CA  1 
ATOM 2596 C C   . THR C 3 161 ? 386.305 321.839 469.061 1.00 61.04  ? 161 THR A C   1 
ATOM 2597 O O   . THR C 3 161 ? 387.003 322.746 468.614 1.00 61.04  ? 161 THR A O   1 
ATOM 2598 C CB  . THR C 3 161 ? 385.048 322.211 471.207 1.00 61.04  ? 161 THR A CB  1 
ATOM 2599 O OG1 . THR C 3 161 ? 383.855 321.859 470.503 1.00 61.04  ? 161 THR A OG1 1 
ATOM 2600 C CG2 . THR C 3 161 ? 385.208 323.671 471.188 1.00 61.04  ? 161 THR A CG2 1 
ATOM 2601 N N   . SER C 3 162 ? 385.579 321.051 468.281 1.00 61.77  ? 162 SER A N   1 
ATOM 2602 C CA  . SER C 3 162 ? 385.723 321.059 466.835 1.00 61.77  ? 162 SER A CA  1 
ATOM 2603 C C   . SER C 3 162 ? 384.829 322.062 466.143 1.00 61.77  ? 162 SER A C   1 
ATOM 2604 O O   . SER C 3 162 ? 384.913 322.206 464.922 1.00 61.77  ? 162 SER A O   1 
ATOM 2605 C CB  . SER C 3 162 ? 385.426 319.677 466.268 1.00 61.77  ? 162 SER A CB  1 
ATOM 2606 O OG  . SER C 3 162 ? 384.997 319.791 464.931 1.00 61.77  ? 162 SER A OG  1 
ATOM 2607 N N   . THR C 3 163 ? 383.965 322.745 466.885 1.00 59.62  ? 163 THR A N   1 
ATOM 2608 C CA  . THR C 3 163 ? 383.032 323.694 466.305 1.00 59.62  ? 163 THR A CA  1 
ATOM 2609 C C   . THR C 3 163 ? 383.400 325.131 466.622 1.00 59.62  ? 163 THR A C   1 
ATOM 2610 O O   . THR C 3 163 ? 382.738 326.049 466.139 1.00 59.62  ? 163 THR A O   1 
ATOM 2611 C CB  . THR C 3 163 ? 381.617 323.395 466.786 1.00 59.62  ? 163 THR A CB  1 
ATOM 2612 O OG1 . THR C 3 163 ? 381.531 323.660 468.188 1.00 59.62  ? 163 THR A OG1 1 
ATOM 2613 C CG2 . THR C 3 163 ? 381.281 321.939 466.546 1.00 59.62  ? 163 THR A CG2 1 
ATOM 2614 N N   . ASN C 3 164 ? 384.438 325.344 467.423 1.00 54.39  ? 164 ASN A N   1 
ATOM 2615 C CA  . ASN C 3 164 ? 384.916 326.685 467.739 1.00 54.39  ? 164 ASN A CA  1 
ATOM 2616 C C   . ASN C 3 164 ? 386.149 326.937 466.893 1.00 54.39  ? 164 ASN A C   1 
ATOM 2617 O O   . ASN C 3 164 ? 387.238 326.461 467.239 1.00 54.39  ? 164 ASN A O   1 
ATOM 2618 C CB  . ASN C 3 164 ? 385.260 326.823 469.223 1.00 54.39  ? 164 ASN A CB  1 
ATOM 2619 C CG  . ASN C 3 164 ? 384.048 326.795 470.122 1.00 54.39  ? 164 ASN A CG  1 
ATOM 2620 O OD1 . ASN C 3 164 ? 384.178 326.823 471.339 1.00 54.39  ? 164 ASN A OD1 1 
ATOM 2621 N ND2 . ASN C 3 164 ? 382.869 326.723 469.538 1.00 54.39  ? 164 ASN A ND2 1 
ATOM 2622 N N   . PRO C 3 165 ? 386.044 327.669 465.788 1.00 51.38  ? 165 PRO A N   1 
ATOM 2623 C CA  . PRO C 3 165 ? 387.191 327.809 464.889 1.00 51.38  ? 165 PRO A CA  1 
ATOM 2624 C C   . PRO C 3 165 ? 388.224 328.758 465.469 1.00 51.38  ? 165 PRO A C   1 
ATOM 2625 O O   . PRO C 3 165 ? 387.887 329.821 465.986 1.00 51.38  ? 165 PRO A O   1 
ATOM 2626 C CB  . PRO C 3 165 ? 386.565 328.368 463.614 1.00 51.38  ? 165 PRO A CB  1 
ATOM 2627 C CG  . PRO C 3 165 ? 385.375 329.088 464.077 1.00 51.38  ? 165 PRO A CG  1 
ATOM 2628 C CD  . PRO C 3 165 ? 384.871 328.403 465.295 1.00 51.38  ? 165 PRO A CD  1 
ATOM 2629 N N   . SER C 3 166 ? 389.485 328.361 465.402 1.00 48.86  ? 166 SER A N   1 
ATOM 2630 C CA  . SER C 3 166 ? 390.562 329.153 465.961 1.00 48.86  ? 166 SER A CA  1 
ATOM 2631 C C   . SER C 3 166 ? 391.681 329.277 464.948 1.00 48.86  ? 166 SER A C   1 
ATOM 2632 O O   . SER C 3 166 ? 391.852 328.419 464.084 1.00 48.86  ? 166 SER A O   1 
ATOM 2633 C CB  . SER C 3 166 ? 391.103 328.537 467.242 1.00 48.86  ? 166 SER A CB  1 
ATOM 2634 O OG  . SER C 3 166 ? 391.319 327.157 467.084 1.00 48.86  ? 166 SER A OG  1 
ATOM 2635 N N   . VAL C 3 167 ? 392.441 330.361 465.058 1.00 44.89  ? 167 VAL A N   1 
ATOM 2636 C CA  . VAL C 3 167 ? 393.631 330.545 464.245 1.00 44.89  ? 167 VAL A CA  1 
ATOM 2637 C C   . VAL C 3 167 ? 394.841 330.384 465.146 1.00 44.89  ? 167 VAL A C   1 
ATOM 2638 O O   . VAL C 3 167 ? 394.793 330.647 466.350 1.00 44.89  ? 167 VAL A O   1 
ATOM 2639 C CB  . VAL C 3 167 ? 393.658 331.896 463.497 1.00 44.89  ? 167 VAL A CB  1 
ATOM 2640 C CG1 . VAL C 3 167 ? 392.385 332.094 462.744 1.00 44.89  ? 167 VAL A CG1 1 
ATOM 2641 C CG2 . VAL C 3 167 ? 393.846 333.034 464.421 1.00 44.89  ? 167 VAL A CG2 1 
ATOM 2642 N N   . PHE C 3 168 ? 395.912 329.872 464.562 1.00 45.81  ? 168 PHE A N   1 
ATOM 2643 C CA  . PHE C 3 168 ? 397.184 329.701 465.240 1.00 45.81  ? 168 PHE A CA  1 
ATOM 2644 C C   . PHE C 3 168 ? 398.197 330.548 464.499 1.00 45.81  ? 168 PHE A C   1 
ATOM 2645 O O   . PHE C 3 168 ? 398.300 330.456 463.274 1.00 45.81  ? 168 PHE A O   1 
ATOM 2646 C CB  . PHE C 3 168 ? 397.636 328.246 465.242 1.00 45.81  ? 168 PHE A CB  1 
ATOM 2647 C CG  . PHE C 3 168 ? 396.788 327.335 466.070 1.00 45.81  ? 168 PHE A CG  1 
ATOM 2648 C CD1 . PHE C 3 168 ? 395.646 326.775 465.550 1.00 45.81  ? 168 PHE A CD1 1 
ATOM 2649 C CD2 . PHE C 3 168 ? 397.164 326.999 467.348 1.00 45.81  ? 168 PHE A CD2 1 
ATOM 2650 C CE1 . PHE C 3 168 ? 394.884 325.932 466.296 1.00 45.81  ? 168 PHE A CE1 1 
ATOM 2651 C CE2 . PHE C 3 168 ? 396.404 326.151 468.093 1.00 45.81  ? 168 PHE A CE2 1 
ATOM 2652 C CZ  . PHE C 3 168 ? 395.265 325.619 467.565 1.00 45.81  ? 168 PHE A CZ  1 
ATOM 2653 N N   . TRP C 3 169 ? 398.941 331.367 465.228 1.00 50.31  ? 169 TRP A N   1 
ATOM 2654 C CA  . TRP C 3 169 ? 399.797 332.358 464.599 1.00 50.31  ? 169 TRP A CA  1 
ATOM 2655 C C   . TRP C 3 169 ? 401.115 332.424 465.345 1.00 50.31  ? 169 TRP A C   1 
ATOM 2656 O O   . TRP C 3 169 ? 401.127 332.618 466.559 1.00 50.31  ? 169 TRP A O   1 
ATOM 2657 C CB  . TRP C 3 169 ? 399.105 333.714 464.583 1.00 50.31  ? 169 TRP A CB  1 
ATOM 2658 C CG  . TRP C 3 169 ? 399.971 334.834 464.176 1.00 50.31  ? 169 TRP A CG  1 
ATOM 2659 C CD1 . TRP C 3 169 ? 400.286 335.205 462.912 1.00 50.31  ? 169 TRP A CD1 1 
ATOM 2660 C CD2 . TRP C 3 169 ? 400.623 335.755 465.042 1.00 50.31  ? 169 TRP A CD2 1 
ATOM 2661 N NE1 . TRP C 3 169 ? 401.106 336.296 462.935 1.00 50.31  ? 169 TRP A NE1 1 
ATOM 2662 C CE2 . TRP C 3 169 ? 401.324 336.654 464.236 1.00 50.31  ? 169 TRP A CE2 1 
ATOM 2663 C CE3 . TRP C 3 169 ? 400.686 335.900 466.425 1.00 50.31  ? 169 TRP A CE3 1 
ATOM 2664 C CZ2 . TRP C 3 169 ? 402.078 337.677 464.762 1.00 50.31  ? 169 TRP A CZ2 1 
ATOM 2665 C CZ3 . TRP C 3 169 ? 401.428 336.908 466.940 1.00 50.31  ? 169 TRP A CZ3 1 
ATOM 2666 C CH2 . TRP C 3 169 ? 402.118 337.787 466.115 1.00 50.31  ? 169 TRP A CH2 1 
ATOM 2667 N N   . THR C 3 170 ? 402.212 332.251 464.620 1.00 53.10  ? 170 THR A N   1 
ATOM 2668 C CA  . THR C 3 170 ? 403.553 332.322 465.165 1.00 53.10  ? 170 THR A CA  1 
ATOM 2669 C C   . THR C 3 170 ? 404.078 333.745 465.036 1.00 53.10  ? 170 THR A C   1 
ATOM 2670 O O   . THR C 3 170 ? 403.850 334.416 464.033 1.00 53.10  ? 170 THR A O   1 
ATOM 2671 C CB  . THR C 3 170 ? 404.459 331.348 464.417 1.00 53.10  ? 170 THR A CB  1 
ATOM 2672 O OG1 . THR C 3 170 ? 403.851 330.054 464.410 1.00 53.10  ? 170 THR A OG1 1 
ATOM 2673 C CG2 . THR C 3 170 ? 405.810 331.220 465.077 1.00 53.10  ? 170 THR A CG2 1 
ATOM 2674 N N   . GLU C 3 171 ? 404.786 334.203 466.066 1.00 56.80  ? 171 GLU A N   1 
ATOM 2675 C CA  . GLU C 3 171 ? 405.242 335.583 466.163 1.00 56.80  ? 171 GLU A CA  1 
ATOM 2676 C C   . GLU C 3 171 ? 406.272 335.915 465.098 1.00 56.80  ? 171 GLU A C   1 
ATOM 2677 O O   . GLU C 3 171 ? 407.104 335.082 464.743 1.00 56.80  ? 171 GLU A O   1 
ATOM 2678 C CB  . GLU C 3 171 ? 405.848 335.852 467.534 1.00 56.80  ? 171 GLU A CB  1 
ATOM 2679 C CG  . GLU C 3 171 ? 404.857 336.292 468.574 1.00 56.80  ? 171 GLU A CG  1 
ATOM 2680 C CD  . GLU C 3 171 ? 405.494 337.148 469.639 1.00 56.80  ? 171 GLU A CD  1 
ATOM 2681 O OE1 . GLU C 3 171 ? 406.224 336.600 470.486 1.00 56.80  ? 171 GLU A OE1 1 
ATOM 2682 O OE2 . GLU C 3 171 ? 405.270 338.373 469.623 1.00 56.80  ? 171 GLU A OE2 1 
ATOM 2683 N N   . GLY C 3 172 ? 406.216 337.140 464.601 1.00 53.66  ? 172 GLY A N   1 
ATOM 2684 C CA  . GLY C 3 172 ? 407.114 337.581 463.563 1.00 53.66  ? 172 GLY A CA  1 
ATOM 2685 C C   . GLY C 3 172 ? 406.561 337.543 462.160 1.00 53.66  ? 172 GLY A C   1 
ATOM 2686 O O   . GLY C 3 172 ? 407.334 337.679 461.210 1.00 53.66  ? 172 GLY A O   1 
ATOM 2687 N N   . ASN C 3 173 ? 405.255 337.379 462.000 1.00 52.92  ? 173 ASN A N   1 
ATOM 2688 C CA  . ASN C 3 173 ? 404.632 337.333 460.687 1.00 52.92  ? 173 ASN A CA  1 
ATOM 2689 C C   . ASN C 3 173 ? 403.620 338.459 460.570 1.00 52.92  ? 173 ASN A C   1 
ATOM 2690 O O   . ASN C 3 173 ? 403.559 339.331 461.439 1.00 52.92  ? 173 ASN A O   1 
ATOM 2691 C CB  . ASN C 3 173 ? 403.942 335.992 460.458 1.00 52.92  ? 173 ASN A CB  1 
ATOM 2692 C CG  . ASN C 3 173 ? 404.910 334.852 460.285 1.00 52.92  ? 173 ASN A CG  1 
ATOM 2693 O OD1 . ASN C 3 173 ? 405.176 334.416 459.172 1.00 52.92  ? 173 ASN A OD1 1 
ATOM 2694 N ND2 . ASN C 3 173 ? 405.430 334.349 461.387 1.00 52.92  ? 173 ASN A ND2 1 
ATOM 2695 N N   . ALA C 3 174 ? 402.835 338.455 459.501 1.00 50.63  ? 174 ALA A N   1 
ATOM 2696 C CA  . ALA C 3 174 ? 401.729 339.384 459.380 1.00 50.63  ? 174 ALA A CA  1 
ATOM 2697 C C   . ALA C 3 174 ? 400.664 339.065 460.429 1.00 50.63  ? 174 ALA A C   1 
ATOM 2698 O O   . ALA C 3 174 ? 400.551 337.920 460.866 1.00 50.63  ? 174 ALA A O   1 
ATOM 2699 C CB  . ALA C 3 174 ? 401.132 339.306 457.982 1.00 50.63  ? 174 ALA A CB  1 
ATOM 2700 N N   . PRO C 3 175 ? 399.899 340.065 460.875 1.00 48.98  ? 175 PRO A N   1 
ATOM 2701 C CA  . PRO C 3 175 ? 398.947 339.828 461.960 1.00 48.98  ? 175 PRO A CA  1 
ATOM 2702 C C   . PRO C 3 175 ? 397.801 338.928 461.534 1.00 48.98  ? 175 PRO A C   1 
ATOM 2703 O O   . PRO C 3 175 ? 397.505 338.799 460.335 1.00 48.98  ? 175 PRO A O   1 
ATOM 2704 C CB  . PRO C 3 175 ? 398.454 341.245 462.308 1.00 48.98  ? 175 PRO A CB  1 
ATOM 2705 C CG  . PRO C 3 175 ? 398.977 342.119 461.257 1.00 48.98  ? 175 PRO A CG  1 
ATOM 2706 C CD  . PRO C 3 175 ? 400.203 341.493 460.753 1.00 48.98  ? 175 PRO A CD  1 
ATOM 2707 N N   . PRO C 3 176 ? 397.163 338.238 462.477 1.00 48.69  ? 176 PRO A N   1 
ATOM 2708 C CA  . PRO C 3 176 ? 396.138 337.248 462.126 1.00 48.69  ? 176 PRO A CA  1 
ATOM 2709 C C   . PRO C 3 176 ? 394.724 337.760 461.893 1.00 48.69  ? 176 PRO A C   1 
ATOM 2710 O O   . PRO C 3 176 ? 393.923 337.795 462.824 1.00 48.69  ? 176 PRO A O   1 
ATOM 2711 C CB  . PRO C 3 176 ? 396.175 336.297 463.323 1.00 48.69  ? 176 PRO A CB  1 
ATOM 2712 C CG  . PRO C 3 176 ? 396.676 337.093 464.417 1.00 48.69  ? 176 PRO A CG  1 
ATOM 2713 C CD  . PRO C 3 176 ? 397.619 338.069 463.863 1.00 48.69  ? 176 PRO A CD  1 
ATOM 2714 N N   . ARG C 3 177 ? 394.385 338.149 460.674 1.00 54.26  ? 177 ARG A N   1 
ATOM 2715 C CA  . ARG C 3 177 ? 393.018 338.553 460.376 1.00 54.26  ? 177 ARG A CA  1 
ATOM 2716 C C   . ARG C 3 177 ? 392.082 337.354 460.246 1.00 54.26  ? 177 ARG A C   1 
ATOM 2717 O O   . ARG C 3 177 ? 392.455 336.302 459.732 1.00 54.26  ? 177 ARG A O   1 
ATOM 2718 C CB  . ARG C 3 177 ? 392.981 339.354 459.081 1.00 54.26  ? 177 ARG A CB  1 
ATOM 2719 C CG  . ARG C 3 177 ? 391.767 340.217 458.940 1.00 54.26  ? 177 ARG A CG  1 
ATOM 2720 C CD  . ARG C 3 177 ? 391.605 340.746 457.551 1.00 54.26  ? 177 ARG A CD  1 
ATOM 2721 N NE  . ARG C 3 177 ? 392.716 341.585 457.136 1.00 54.26  ? 177 ARG A NE  1 
ATOM 2722 C CZ  . ARG C 3 177 ? 392.810 342.878 457.403 1.00 54.26  ? 177 ARG A CZ  1 
ATOM 2723 N NH1 . ARG C 3 177 ? 391.871 343.479 458.107 1.00 54.26  ? 177 ARG A NH1 1 
ATOM 2724 N NH2 . ARG C 3 177 ? 393.851 343.571 456.976 1.00 54.26  ? 177 ARG A NH2 1 
ATOM 2725 N N   . MET C 3 178 ? 390.846 337.529 460.715 1.00 59.43  ? 178 MET A N   1 
ATOM 2726 C CA  . MET C 3 178 ? 389.758 336.589 460.468 1.00 59.43  ? 178 MET A CA  1 
ATOM 2727 C C   . MET C 3 178 ? 388.473 337.383 460.286 1.00 59.43  ? 178 MET A C   1 
ATOM 2728 O O   . MET C 3 178 ? 388.372 338.532 460.712 1.00 59.43  ? 178 MET A O   1 
ATOM 2729 C CB  . MET C 3 178 ? 389.609 335.569 461.599 1.00 59.43  ? 178 MET A CB  1 
ATOM 2730 C CG  . MET C 3 178 ? 388.851 336.076 462.799 1.00 59.43  ? 178 MET A CG  1 
ATOM 2731 S SD  . MET C 3 178 ? 389.292 335.262 464.342 1.00 59.43  ? 178 MET A SD  1 
ATOM 2732 C CE  . MET C 3 178 ? 388.617 333.632 464.086 1.00 59.43  ? 178 MET A CE  1 
ATOM 2733 N N   . SER C 3 179 ? 387.486 336.767 459.644 1.00 58.84  ? 179 SER A N   1 
ATOM 2734 C CA  . SER C 3 179 ? 386.280 337.469 459.226 1.00 58.84  ? 179 SER A CA  1 
ATOM 2735 C C   . SER C 3 179 ? 385.036 336.694 459.619 1.00 58.84  ? 179 SER A C   1 
ATOM 2736 O O   . SER C 3 179 ? 384.980 335.477 459.435 1.00 58.84  ? 179 SER A O   1 
ATOM 2737 C CB  . SER C 3 179 ? 386.274 337.680 457.727 1.00 58.84  ? 179 SER A CB  1 
ATOM 2738 O OG  . SER C 3 179 ? 385.048 338.244 457.316 1.00 58.84  ? 179 SER A OG  1 
ATOM 2739 N N   . ILE C 3 180 ? 384.028 337.399 460.106 1.00 55.91  ? 180 ILE A N   1 
ATOM 2740 C CA  . ILE C 3 180 ? 382.839 336.798 460.706 1.00 55.91  ? 180 ILE A CA  1 
ATOM 2741 C C   . ILE C 3 180 ? 381.614 337.355 459.995 1.00 55.91  ? 180 ILE A C   1 
ATOM 2742 O O   . ILE C 3 180 ? 381.462 338.577 459.924 1.00 55.91  ? 180 ILE A O   1 
ATOM 2743 C CB  . ILE C 3 180 ? 382.775 337.089 462.215 1.00 55.91  ? 180 ILE A CB  1 
ATOM 2744 C CG1 . ILE C 3 180 ? 383.856 336.300 462.936 1.00 55.91  ? 180 ILE A CG1 1 
ATOM 2745 C CG2 . ILE C 3 180 ? 381.421 336.789 462.783 1.00 55.91  ? 180 ILE A CG2 1 
ATOM 2746 C CD1 . ILE C 3 180 ? 384.083 336.755 464.327 1.00 55.91  ? 180 ILE A CD1 1 
ATOM 2747 N N   . PRO C 3 181 ? 380.722 336.521 459.480 1.00 56.48  ? 181 PRO A N   1 
ATOM 2748 C CA  . PRO C 3 181 ? 379.583 337.014 458.705 1.00 56.48  ? 181 PRO A CA  1 
ATOM 2749 C C   . PRO C 3 181 ? 378.494 337.546 459.628 1.00 56.48  ? 181 PRO A C   1 
ATOM 2750 O O   . PRO C 3 181 ? 378.679 337.681 460.829 1.00 56.48  ? 181 PRO A O   1 
ATOM 2751 C CB  . PRO C 3 181 ? 379.124 335.771 457.963 1.00 56.48  ? 181 PRO A CB  1 
ATOM 2752 C CG  . PRO C 3 181 ? 379.391 334.696 458.920 1.00 56.48  ? 181 PRO A CG  1 
ATOM 2753 C CD  . PRO C 3 181 ? 380.658 335.063 459.640 1.00 56.48  ? 181 PRO A CD  1 
ATOM 2754 N N   . PHE C 3 182 ? 377.348 337.869 459.041 1.00 55.32  ? 182 PHE A N   1 
ATOM 2755 C CA  . PHE C 3 182 ? 376.225 338.367 459.827 1.00 55.32  ? 182 PHE A CA  1 
ATOM 2756 C C   . PHE C 3 182 ? 375.644 337.198 460.597 1.00 55.32  ? 182 PHE A C   1 
ATOM 2757 O O   . PHE C 3 182 ? 374.816 336.453 460.085 1.00 55.32  ? 182 PHE A O   1 
ATOM 2758 C CB  . PHE C 3 182 ? 375.173 339.012 458.940 1.00 55.32  ? 182 PHE A CB  1 
ATOM 2759 C CG  . PHE C 3 182 ? 373.943 339.409 459.681 1.00 55.32  ? 182 PHE A CG  1 
ATOM 2760 C CD1 . PHE C 3 182 ? 373.991 340.410 460.618 1.00 55.32  ? 182 PHE A CD1 1 
ATOM 2761 C CD2 . PHE C 3 182 ? 372.746 338.771 459.457 1.00 55.32  ? 182 PHE A CD2 1 
ATOM 2762 C CE1 . PHE C 3 182 ? 372.876 340.767 461.312 1.00 55.32  ? 182 PHE A CE1 1 
ATOM 2763 C CE2 . PHE C 3 182 ? 371.627 339.129 460.152 1.00 55.32  ? 182 PHE A CE2 1 
ATOM 2764 C CZ  . PHE C 3 182 ? 371.694 340.125 461.080 1.00 55.32  ? 182 PHE A CZ  1 
ATOM 2765 N N   . ILE C 3 183 ? 376.070 337.021 461.834 1.00 57.48  ? 183 ILE A N   1 
ATOM 2766 C CA  . ILE C 3 183 ? 375.752 335.814 462.575 1.00 57.48  ? 183 ILE A CA  1 
ATOM 2767 C C   . ILE C 3 183 ? 374.646 336.125 463.577 1.00 57.48  ? 183 ILE A C   1 
ATOM 2768 O O   . ILE C 3 183 ? 374.896 336.533 464.715 1.00 57.48  ? 183 ILE A O   1 
ATOM 2769 C CB  . ILE C 3 183 ? 377.016 335.198 463.199 1.00 57.48  ? 183 ILE A CB  1 
ATOM 2770 C CG1 . ILE C 3 183 ? 376.708 333.898 463.926 1.00 57.48  ? 183 ILE A CG1 1 
ATOM 2771 C CG2 . ILE C 3 183 ? 377.905 336.214 463.948 1.00 57.48  ? 183 ILE A CG2 1 
ATOM 2772 C CD1 . ILE C 3 183 ? 377.926 333.258 464.471 1.00 57.48  ? 183 ILE A CD1 1 
ATOM 2773 N N   . SER C 3 184 ? 373.406 335.929 463.141 1.00 58.36  ? 184 SER A N   1 
ATOM 2774 C CA  . SER C 3 184 ? 372.234 336.158 463.972 1.00 58.36  ? 184 SER A CA  1 
ATOM 2775 C C   . SER C 3 184 ? 371.045 335.477 463.324 1.00 58.36  ? 184 SER A C   1 
ATOM 2776 O O   . SER C 3 184 ? 371.102 335.067 462.164 1.00 58.36  ? 184 SER A O   1 
ATOM 2777 C CB  . SER C 3 184 ? 371.932 337.642 464.158 1.00 58.36  ? 184 SER A CB  1 
ATOM 2778 O OG  . SER C 3 184 ? 370.686 337.806 464.794 1.00 58.36  ? 184 SER A OG  1 
ATOM 2779 N N   . ILE C 3 185 ? 369.959 335.374 464.083 1.00 57.54  ? 185 ILE A N   1 
ATOM 2780 C CA  . ILE C 3 185 ? 368.759 334.742 463.554 1.00 57.54  ? 185 ILE A CA  1 
ATOM 2781 C C   . ILE C 3 185 ? 367.778 335.787 463.047 1.00 57.54  ? 185 ILE A C   1 
ATOM 2782 O O   . ILE C 3 185 ? 367.102 335.577 462.036 1.00 57.54  ? 185 ILE A O   1 
ATOM 2783 C CB  . ILE C 3 185 ? 368.132 333.838 464.620 1.00 57.54  ? 185 ILE A CB  1 
ATOM 2784 C CG1 . ILE C 3 185 ? 369.210 332.974 465.255 1.00 57.54  ? 185 ILE A CG1 1 
ATOM 2785 C CG2 . ILE C 3 185 ? 367.067 332.959 464.006 1.00 57.54  ? 185 ILE A CG2 1 
ATOM 2786 C CD1 . ILE C 3 185 ? 369.822 331.983 464.303 1.00 57.54  ? 185 ILE A CD1 1 
ATOM 2787 N N   . GLY C 3 186 ? 367.680 336.920 463.726 1.00 58.68  ? 186 GLY A N   1 
ATOM 2788 C CA  . GLY C 3 186 ? 366.882 338.014 463.224 1.00 58.68  ? 186 GLY A CA  1 
ATOM 2789 C C   . GLY C 3 186 ? 367.510 338.633 461.998 1.00 58.68  ? 186 GLY A C   1 
ATOM 2790 O O   . GLY C 3 186 ? 368.679 338.432 461.688 1.00 58.68  ? 186 GLY A O   1 
ATOM 2791 N N   . ASN C 3 187 ? 366.722 339.412 461.278 1.00 60.92  ? 187 ASN A N   1 
ATOM 2792 C CA  . ASN C 3 187 ? 367.206 339.909 460.003 1.00 60.92  ? 187 ASN A CA  1 
ATOM 2793 C C   . ASN C 3 187 ? 368.053 341.164 460.120 1.00 60.92  ? 187 ASN A C   1 
ATOM 2794 O O   . ASN C 3 187 ? 368.442 341.709 459.084 1.00 60.92  ? 187 ASN A O   1 
ATOM 2795 C CB  . ASN C 3 187 ? 366.031 340.170 459.078 1.00 60.92  ? 187 ASN A CB  1 
ATOM 2796 C CG  . ASN C 3 187 ? 365.077 339.015 459.036 1.00 60.92  ? 187 ASN A CG  1 
ATOM 2797 O OD1 . ASN C 3 187 ? 364.436 338.699 460.029 1.00 60.92  ? 187 ASN A OD1 1 
ATOM 2798 N ND2 . ASN C 3 187 ? 364.974 338.373 457.886 1.00 60.92  ? 187 ASN A ND2 1 
ATOM 2799 N N   . ALA C 3 188 ? 368.341 341.631 461.333 1.00 55.17  ? 188 ALA A N   1 
ATOM 2800 C CA  . ALA C 3 188 ? 369.176 342.801 461.551 1.00 55.17  ? 188 ALA A CA  1 
ATOM 2801 C C   . ALA C 3 188 ? 369.630 342.822 462.998 1.00 55.17  ? 188 ALA A C   1 
ATOM 2802 O O   . ALA C 3 188 ? 368.898 342.403 463.891 1.00 55.17  ? 188 ALA A O   1 
ATOM 2803 C CB  . ALA C 3 188 ? 368.430 344.094 461.238 1.00 55.17  ? 188 ALA A CB  1 
ATOM 2804 N N   . TYR C 3 189 ? 370.843 343.311 463.222 1.00 55.95  ? 189 TYR A N   1 
ATOM 2805 C CA  . TYR C 3 189 ? 371.248 343.639 464.574 1.00 55.95  ? 189 TYR A CA  1 
ATOM 2806 C C   . TYR C 3 189 ? 370.445 344.834 465.044 1.00 55.95  ? 189 TYR A C   1 
ATOM 2807 O O   . TYR C 3 189 ? 370.073 345.699 464.259 1.00 55.95  ? 189 TYR A O   1 
ATOM 2808 C CB  . TYR C 3 189 ? 372.733 343.980 464.643 1.00 55.95  ? 189 TYR A CB  1 
ATOM 2809 C CG  . TYR C 3 189 ? 373.662 342.811 464.479 1.00 55.95  ? 189 TYR A CG  1 
ATOM 2810 C CD1 . TYR C 3 189 ? 373.513 341.676 465.243 1.00 55.95  ? 189 TYR A CD1 1 
ATOM 2811 C CD2 . TYR C 3 189 ? 374.686 342.847 463.555 1.00 55.95  ? 189 TYR A CD2 1 
ATOM 2812 C CE1 . TYR C 3 189 ? 374.350 340.615 465.096 1.00 55.95  ? 189 TYR A CE1 1 
ATOM 2813 C CE2 . TYR C 3 189 ? 375.529 341.789 463.404 1.00 55.95  ? 189 TYR A CE2 1 
ATOM 2814 C CZ  . TYR C 3 189 ? 375.355 340.679 464.176 1.00 55.95  ? 189 TYR A CZ  1 
ATOM 2815 O OH  . TYR C 3 189 ? 376.201 339.615 464.024 1.00 55.95  ? 189 TYR A OH  1 
ATOM 2816 N N   . SER C 3 190 ? 370.173 344.885 466.335 1.00 58.98  ? 190 SER A N   1 
ATOM 2817 C CA  . SER C 3 190 ? 369.347 345.945 466.891 1.00 58.98  ? 190 SER A CA  1 
ATOM 2818 C C   . SER C 3 190 ? 370.160 346.682 467.938 1.00 58.98  ? 190 SER A C   1 
ATOM 2819 O O   . SER C 3 190 ? 370.679 346.066 468.872 1.00 58.98  ? 190 SER A O   1 
ATOM 2820 C CB  . SER C 3 190 ? 368.065 345.384 467.489 1.00 58.98  ? 190 SER A CB  1 
ATOM 2821 O OG  . SER C 3 190 ? 367.397 346.375 468.237 1.00 58.98  ? 190 SER A OG  1 
ATOM 2822 N N   . CYS C 3 191 ? 370.281 347.996 467.778 1.00 61.49  ? 191 CYS A N   1 
ATOM 2823 C CA  . CYS C 3 191 ? 370.993 348.795 468.760 1.00 61.49  ? 191 CYS A CA  1 
ATOM 2824 C C   . CYS C 3 191 ? 370.157 349.083 469.989 1.00 61.49  ? 191 CYS A C   1 
ATOM 2825 O O   . CYS C 3 191 ? 370.708 349.166 471.088 1.00 61.49  ? 191 CYS A O   1 
ATOM 2826 C CB  . CYS C 3 191 ? 371.442 350.111 468.140 1.00 61.49  ? 191 CYS A CB  1 
ATOM 2827 S SG  . CYS C 3 191 ? 372.457 349.912 466.684 1.00 61.49  ? 191 CYS A SG  1 
ATOM 2828 N N   . PHE C 3 192 ? 368.847 349.235 469.825 1.00 59.58  ? 192 PHE A N   1 
ATOM 2829 C CA  . PHE C 3 192 ? 367.940 349.526 470.919 1.00 59.58  ? 192 PHE A CA  1 
ATOM 2830 C C   . PHE C 3 192 ? 366.837 348.486 470.912 1.00 59.58  ? 192 PHE A C   1 
ATOM 2831 O O   . PHE C 3 192 ? 366.419 348.014 469.856 1.00 59.58  ? 192 PHE A O   1 
ATOM 2832 C CB  . PHE C 3 192 ? 367.338 350.921 470.794 1.00 59.58  ? 192 PHE A CB  1 
ATOM 2833 C CG  . PHE C 3 192 ? 368.341 352.022 470.886 1.00 59.58  ? 192 PHE A CG  1 
ATOM 2834 C CD1 . PHE C 3 192 ? 369.005 352.472 469.764 1.00 59.58  ? 192 PHE A CD1 1 
ATOM 2835 C CD2 . PHE C 3 192 ? 368.611 352.619 472.098 1.00 59.58  ? 192 PHE A CD2 1 
ATOM 2836 C CE1 . PHE C 3 192 ? 369.922 353.477 469.856 1.00 59.58  ? 192 PHE A CE1 1 
ATOM 2837 C CE2 . PHE C 3 192 ? 369.525 353.632 472.190 1.00 59.58  ? 192 PHE A CE2 1 
ATOM 2838 C CZ  . PHE C 3 192 ? 370.176 354.062 471.069 1.00 59.58  ? 192 PHE A CZ  1 
ATOM 2839 N N   . TYR C 3 193 ? 366.360 348.131 472.099 1.00 60.14  ? 193 TYR A N   1 
ATOM 2840 C CA  . TYR C 3 193 ? 365.337 347.099 472.219 1.00 60.14  ? 193 TYR A CA  1 
ATOM 2841 C C   . TYR C 3 193 ? 364.457 347.443 473.407 1.00 60.14  ? 193 TYR A C   1 
ATOM 2842 O O   . TYR C 3 193 ? 364.915 347.392 474.547 1.00 60.14  ? 193 TYR A O   1 
ATOM 2843 C CB  . TYR C 3 193 ? 365.970 345.732 472.389 1.00 60.14  ? 193 TYR A CB  1 
ATOM 2844 C CG  . TYR C 3 193 ? 364.993 344.617 472.621 1.00 60.14  ? 193 TYR A CG  1 
ATOM 2845 C CD1 . TYR C 3 193 ? 364.115 344.226 471.636 1.00 60.14  ? 193 TYR A CD1 1 
ATOM 2846 C CD2 . TYR C 3 193 ? 364.964 343.945 473.825 1.00 60.14  ? 193 TYR A CD2 1 
ATOM 2847 C CE1 . TYR C 3 193 ? 363.232 343.208 471.847 1.00 60.14  ? 193 TYR A CE1 1 
ATOM 2848 C CE2 . TYR C 3 193 ? 364.088 342.927 474.042 1.00 60.14  ? 193 TYR A CE2 1 
ATOM 2849 C CZ  . TYR C 3 193 ? 363.226 342.565 473.053 1.00 60.14  ? 193 TYR A CZ  1 
ATOM 2850 O OH  . TYR C 3 193 ? 362.344 341.546 473.272 1.00 60.14  ? 193 TYR A OH  1 
ATOM 2851 N N   . ASP C 3 194 ? 363.204 347.783 473.146 1.00 62.68  ? 194 ASP A N   1 
ATOM 2852 C CA  . ASP C 3 194 ? 362.275 348.183 474.196 1.00 62.68  ? 194 ASP A CA  1 
ATOM 2853 C C   . ASP C 3 194 ? 361.490 346.960 474.636 1.00 62.68  ? 194 ASP A C   1 
ATOM 2854 O O   . ASP C 3 194 ? 360.369 346.735 474.195 1.00 62.68  ? 194 ASP A O   1 
ATOM 2855 C CB  . ASP C 3 194 ? 361.344 349.277 473.710 1.00 62.68  ? 194 ASP A CB  1 
ATOM 2856 C CG  . ASP C 3 194 ? 360.565 349.916 474.835 1.00 62.68  ? 194 ASP A CG  1 
ATOM 2857 O OD1 . ASP C 3 194 ? 360.880 349.661 476.015 1.00 62.68  ? 194 ASP A OD1 1 
ATOM 2858 O OD2 . ASP C 3 194 ? 359.635 350.689 474.540 1.00 62.68  ? 194 ASP A OD2 1 
ATOM 2859 N N   . GLY C 3 195 ? 362.068 346.179 475.534 1.00 60.79  ? 195 GLY A N   1 
ATOM 2860 C CA  . GLY C 3 195 ? 361.366 345.019 476.024 1.00 60.79  ? 195 GLY A CA  1 
ATOM 2861 C C   . GLY C 3 195 ? 362.194 344.161 476.945 1.00 60.79  ? 195 GLY A C   1 
ATOM 2862 O O   . GLY C 3 195 ? 363.263 344.571 477.395 1.00 60.79  ? 195 GLY A O   1 
ATOM 2863 N N   . TRP C 3 196 ? 361.694 342.971 477.242 1.00 60.47  ? 196 TRP A N   1 
ATOM 2864 C CA  . TRP C 3 196 ? 362.386 342.009 478.076 1.00 60.47  ? 196 TRP A CA  1 
ATOM 2865 C C   . TRP C 3 196 ? 362.787 340.815 477.219 1.00 60.47  ? 196 TRP A C   1 
ATOM 2866 O O   . TRP C 3 196 ? 362.405 340.706 476.055 1.00 60.47  ? 196 TRP A O   1 
ATOM 2867 C CB  . TRP C 3 196 ? 361.500 341.607 479.247 1.00 60.47  ? 196 TRP A CB  1 
ATOM 2868 C CG  . TRP C 3 196 ? 361.212 342.728 480.188 1.00 60.47  ? 196 TRP A CG  1 
ATOM 2869 C CD1 . TRP C 3 196 ? 361.825 342.966 481.374 1.00 60.47  ? 196 TRP A CD1 1 
ATOM 2870 C CD2 . TRP C 3 196 ? 360.241 343.765 480.029 1.00 60.47  ? 196 TRP A CD2 1 
ATOM 2871 N NE1 . TRP C 3 196 ? 361.302 344.083 481.967 1.00 60.47  ? 196 TRP A NE1 1 
ATOM 2872 C CE2 . TRP C 3 196 ? 360.327 344.592 481.157 1.00 60.47  ? 196 TRP A CE2 1 
ATOM 2873 C CE3 . TRP C 3 196 ? 359.302 344.072 479.044 1.00 60.47  ? 196 TRP A CE3 1 
ATOM 2874 C CZ2 . TRP C 3 196 ? 359.523 345.699 481.324 1.00 60.47  ? 196 TRP A CZ2 1 
ATOM 2875 C CZ3 . TRP C 3 196 ? 358.509 345.168 479.211 1.00 60.47  ? 196 TRP A CZ3 1 
ATOM 2876 C CH2 . TRP C 3 196 ? 358.621 345.969 480.341 1.00 60.47  ? 196 TRP A CH2 1 
ATOM 2877 N N   . THR C 3 197 ? 363.562 339.906 477.788 1.00 56.68  ? 197 THR A N   1 
ATOM 2878 C CA  . THR C 3 197 ? 364.138 338.809 477.017 1.00 56.68  ? 197 THR A CA  1 
ATOM 2879 C C   . THR C 3 197 ? 363.131 337.736 476.608 1.00 56.68  ? 197 THR A C   1 
ATOM 2880 O O   . THR C 3 197 ? 363.023 337.375 475.434 1.00 56.68  ? 197 THR A O   1 
ATOM 2881 C CB  . THR C 3 197 ? 365.254 338.143 477.801 1.00 56.68  ? 197 THR A CB  1 
ATOM 2882 O OG1 . THR C 3 197 ? 366.153 339.145 478.278 1.00 56.68  ? 197 THR A OG1 1 
ATOM 2883 C CG2 . THR C 3 197 ? 366.011 337.199 476.921 1.00 56.68  ? 197 THR A CG2 1 
ATOM 2884 N N   . VAL C 3 204 ? 364.880 340.466 482.247 1.00 63.30  ? 204 VAL A N   1 
ATOM 2885 C CA  . VAL C 3 204 ? 365.791 341.599 482.309 1.00 63.30  ? 204 VAL A CA  1 
ATOM 2886 C C   . VAL C 3 204 ? 365.474 342.554 481.156 1.00 63.30  ? 204 VAL A C   1 
ATOM 2887 O O   . VAL C 3 204 ? 365.192 342.124 480.046 1.00 63.30  ? 204 VAL A O   1 
ATOM 2888 C CB  . VAL C 3 204 ? 367.260 341.110 482.315 1.00 63.30  ? 204 VAL A CB  1 
ATOM 2889 C CG1 . VAL C 3 204 ? 367.541 340.197 481.146 1.00 63.30  ? 204 VAL A CG1 1 
ATOM 2890 C CG2 . VAL C 3 204 ? 368.239 342.267 482.355 1.00 63.30  ? 204 VAL A CG2 1 
ATOM 2891 N N   . TYR C 3 205 ? 365.477 343.854 481.428 1.00 60.24  ? 205 TYR A N   1 
ATOM 2892 C CA  . TYR C 3 205 ? 364.917 344.842 480.518 1.00 60.24  ? 205 TYR A CA  1 
ATOM 2893 C C   . TYR C 3 205 ? 365.944 345.293 479.490 1.00 60.24  ? 205 TYR A C   1 
ATOM 2894 O O   . TYR C 3 205 ? 367.053 345.696 479.846 1.00 60.24  ? 205 TYR A O   1 
ATOM 2895 C CB  . TYR C 3 205 ? 364.395 346.053 481.291 1.00 60.24  ? 205 TYR A CB  1 
ATOM 2896 C CG  . TYR C 3 205 ? 363.956 347.182 480.399 1.00 60.24  ? 205 TYR A CG  1 
ATOM 2897 C CD1 . TYR C 3 205 ? 362.915 347.015 479.509 1.00 60.24  ? 205 TYR A CD1 1 
ATOM 2898 C CD2 . TYR C 3 205 ? 364.580 348.408 480.444 1.00 60.24  ? 205 TYR A CD2 1 
ATOM 2899 C CE1 . TYR C 3 205 ? 362.515 348.030 478.691 1.00 60.24  ? 205 TYR A CE1 1 
ATOM 2900 C CE2 . TYR C 3 205 ? 364.184 349.429 479.625 1.00 60.24  ? 205 TYR A CE2 1 
ATOM 2901 C CZ  . TYR C 3 205 ? 363.153 349.230 478.754 1.00 60.24  ? 205 TYR A CZ  1 
ATOM 2902 O OH  . TYR C 3 205 ? 362.752 350.247 477.936 1.00 60.24  ? 205 TYR A OH  1 
ATOM 2903 N N   . GLY C 3 206 ? 365.560 345.237 478.221 1.00 60.37  ? 206 GLY A N   1 
ATOM 2904 C CA  . GLY C 3 206 ? 366.324 345.834 477.145 1.00 60.37  ? 206 GLY A CA  1 
ATOM 2905 C C   . GLY C 3 206 ? 367.625 345.147 476.818 1.00 60.37  ? 206 GLY A C   1 
ATOM 2906 O O   . GLY C 3 206 ? 368.646 345.813 476.649 1.00 60.37  ? 206 GLY A O   1 
ATOM 2907 N N   . ILE C 3 207 ? 367.610 343.821 476.698 1.00 59.95  ? 207 ILE A N   1 
ATOM 2908 C CA  . ILE C 3 207 ? 368.816 343.035 476.477 1.00 59.95  ? 207 ILE A CA  1 
ATOM 2909 C C   . ILE C 3 207 ? 368.879 342.490 475.057 1.00 59.95  ? 207 ILE A C   1 
ATOM 2910 O O   . ILE C 3 207 ? 369.887 342.669 474.365 1.00 59.95  ? 207 ILE A O   1 
ATOM 2911 C CB  . ILE C 3 207 ? 368.947 341.901 477.513 1.00 59.95  ? 207 ILE A CB  1 
ATOM 2912 C CG1 . ILE C 3 207 ? 369.449 342.480 478.828 1.00 59.95  ? 207 ILE A CG1 1 
ATOM 2913 C CG2 . ILE C 3 207 ? 369.903 340.838 477.058 1.00 59.95  ? 207 ILE A CG2 1 
ATOM 2914 C CD1 . ILE C 3 207 ? 370.757 343.198 478.710 1.00 59.95  ? 207 ILE A CD1 1 
ATOM 2915 N N   . ASN C 3 208 ? 367.794 341.855 474.594 1.00 61.50  ? 208 ASN A N   1 
ATOM 2916 C CA  . ASN C 3 208 ? 367.670 341.290 473.244 1.00 61.50  ? 208 ASN A CA  1 
ATOM 2917 C C   . ASN C 3 208 ? 368.757 340.250 472.980 1.00 61.50  ? 208 ASN A C   1 
ATOM 2918 O O   . ASN C 3 208 ? 369.744 340.507 472.308 1.00 61.50  ? 208 ASN A O   1 
ATOM 2919 C CB  . ASN C 3 208 ? 367.681 342.357 472.141 1.00 61.50  ? 208 ASN A CB  1 
ATOM 2920 C CG  . ASN C 3 208 ? 367.311 341.793 470.783 1.00 61.50  ? 208 ASN A CG  1 
ATOM 2921 O OD1 . ASN C 3 208 ? 366.736 340.715 470.679 1.00 61.50  ? 208 ASN A OD1 1 
ATOM 2922 N ND2 . ASN C 3 208 ? 367.629 342.532 469.735 1.00 61.50  ? 208 ASN A ND2 1 
ATOM 2923 N N   . THR C 3 209 ? 368.568 339.081 473.553 1.00 61.60  ? 209 THR A N   1 
ATOM 2924 C CA  . THR C 3 209 ? 369.496 337.958 473.362 1.00 61.60  ? 209 THR A CA  1 
ATOM 2925 C C   . THR C 3 209 ? 369.634 337.476 471.887 1.00 61.60  ? 209 THR A C   1 
ATOM 2926 O O   . THR C 3 209 ? 370.313 336.484 471.655 1.00 61.60  ? 209 THR A O   1 
ATOM 2927 C CB  . THR C 3 209 ? 369.066 336.782 474.233 1.00 61.60  ? 209 THR A CB  1 
ATOM 2928 O OG1 . THR C 3 209 ? 370.084 335.777 474.210 1.00 61.60  ? 209 THR A OG1 1 
ATOM 2929 C CG2 . THR C 3 209 ? 367.769 336.192 473.721 1.00 61.60  ? 209 THR A CG2 1 
ATOM 2930 N N   . LEU C 3 210 ? 369.025 338.104 470.888 1.00 61.47  ? 210 LEU A N   1 
ATOM 2931 C CA  . LEU C 3 210 ? 369.165 337.661 469.515 1.00 61.47  ? 210 LEU A CA  1 
ATOM 2932 C C   . LEU C 3 210 ? 370.366 338.298 468.830 1.00 61.47  ? 210 LEU A C   1 
ATOM 2933 O O   . LEU C 3 210 ? 370.902 337.720 467.882 1.00 61.47  ? 210 LEU A O   1 
ATOM 2934 C CB  . LEU C 3 210 ? 367.883 337.975 468.751 1.00 61.47  ? 210 LEU A CB  1 
ATOM 2935 C CG  . LEU C 3 210 ? 367.370 336.968 467.732 1.00 61.47  ? 210 LEU A CG  1 
ATOM 2936 C CD1 . LEU C 3 210 ? 366.885 335.733 468.427 1.00 61.47  ? 210 LEU A CD1 1 
ATOM 2937 C CD2 . LEU C 3 210 ? 366.256 337.589 466.950 1.00 61.47  ? 210 LEU A CD2 1 
ATOM 2938 N N   . ASN C 3 211 ? 370.808 339.484 469.262 1.00 61.64  ? 211 ASN A N   1 
ATOM 2939 C CA  . ASN C 3 211 ? 371.982 340.095 468.629 1.00 61.64  ? 211 ASN A CA  1 
ATOM 2940 C C   . ASN C 3 211 ? 373.223 339.785 469.462 1.00 61.64  ? 211 ASN A C   1 
ATOM 2941 O O   . ASN C 3 211 ? 373.929 340.668 469.944 1.00 61.64  ? 211 ASN A O   1 
ATOM 2942 C CB  . ASN C 3 211 ? 371.782 341.587 468.362 1.00 61.64  ? 211 ASN A CB  1 
ATOM 2943 C CG  . ASN C 3 211 ? 371.460 342.415 469.589 1.00 61.64  ? 211 ASN A CG  1 
ATOM 2944 O OD1 . ASN C 3 211 ? 371.558 341.969 470.720 1.00 61.64  ? 211 ASN A OD1 1 
ATOM 2945 N ND2 . ASN C 3 211 ? 371.073 343.658 469.351 1.00 61.64  ? 211 ASN A ND2 1 
ATOM 2946 N N   . ASN C 3 212 ? 373.517 338.497 469.577 1.00 62.68  ? 212 ASN A N   1 
ATOM 2947 C CA  . ASN C 3 212 ? 374.679 337.986 470.287 1.00 62.68  ? 212 ASN A CA  1 
ATOM 2948 C C   . ASN C 3 212 ? 375.690 337.582 469.225 1.00 62.68  ? 212 ASN A C   1 
ATOM 2949 O O   . ASN C 3 212 ? 375.361 336.805 468.326 1.00 62.68  ? 212 ASN A O   1 
ATOM 2950 C CB  . ASN C 3 212 ? 374.278 336.804 471.164 1.00 62.68  ? 212 ASN A CB  1 
ATOM 2951 C CG  . ASN C 3 212 ? 375.347 336.408 472.133 1.00 62.68  ? 212 ASN A CG  1 
ATOM 2952 O OD1 . ASN C 3 212 ? 375.821 335.278 472.120 1.00 62.68  ? 212 ASN A OD1 1 
ATOM 2953 N ND2 . ASN C 3 212 ? 375.732 337.335 472.995 1.00 62.68  ? 212 ASN A ND2 1 
ATOM 2954 N N   . MET C 3 213 ? 376.907 338.119 469.301 1.00 56.74  ? 213 MET A N   1 
ATOM 2955 C CA  . MET C 3 213 ? 377.885 337.884 468.248 1.00 56.74  ? 213 MET A CA  1 
ATOM 2956 C C   . MET C 3 213 ? 378.983 336.899 468.618 1.00 56.74  ? 213 MET A C   1 
ATOM 2957 O O   . MET C 3 213 ? 379.714 336.462 467.729 1.00 56.74  ? 213 MET A O   1 
ATOM 2958 C CB  . MET C 3 213 ? 378.531 339.199 467.816 1.00 56.74  ? 213 MET A CB  1 
ATOM 2959 C CG  . MET C 3 213 ? 377.540 340.279 467.508 1.00 56.74  ? 213 MET A CG  1 
ATOM 2960 S SD  . MET C 3 213 ? 378.310 341.820 467.026 1.00 56.74  ? 213 MET A SD  1 
ATOM 2961 C CE  . MET C 3 213 ? 376.994 342.951 467.416 1.00 56.74  ? 213 MET A CE  1 
ATOM 2962 N N   . GLY C 3 214 ? 379.126 336.532 469.879 1.00 54.65  ? 214 GLY A N   1 
ATOM 2963 C CA  . GLY C 3 214 ? 380.078 335.515 470.267 1.00 54.65  ? 214 GLY A CA  1 
ATOM 2964 C C   . GLY C 3 214 ? 381.134 336.057 471.205 1.00 54.65  ? 214 GLY A C   1 
ATOM 2965 O O   . GLY C 3 214 ? 381.009 337.145 471.761 1.00 54.65  ? 214 GLY A O   1 
ATOM 2966 N N   . THR C 3 215 ? 382.186 335.262 471.387 1.00 51.40  ? 215 THR A N   1 
ATOM 2967 C CA  . THR C 3 215 ? 383.271 335.597 472.296 1.00 51.40  ? 215 THR A CA  1 
ATOM 2968 C C   . THR C 3 215 ? 384.596 335.209 471.649 1.00 51.40  ? 215 THR A C   1 
ATOM 2969 O O   . THR C 3 215 ? 384.632 334.388 470.737 1.00 51.40  ? 215 THR A O   1 
ATOM 2970 C CB  . THR C 3 215 ? 383.091 334.875 473.636 1.00 51.40  ? 215 THR A CB  1 
ATOM 2971 O OG1 . THR C 3 215 ? 381.701 334.801 473.950 1.00 51.40  ? 215 THR A OG1 1 
ATOM 2972 C CG2 . THR C 3 215 ? 383.732 335.646 474.755 1.00 51.40  ? 215 THR A CG2 1 
ATOM 2973 N N   . LEU C 3 216 ? 385.691 335.819 472.104 1.00 50.35  ? 216 LEU A N   1 
ATOM 2974 C CA  . LEU C 3 216 ? 387.033 335.501 471.639 1.00 50.35  ? 216 LEU A CA  1 
ATOM 2975 C C   . LEU C 3 216 ? 387.938 335.221 472.827 1.00 50.35  ? 216 LEU A C   1 
ATOM 2976 O O   . LEU C 3 216 ? 387.868 335.912 473.840 1.00 50.35  ? 216 LEU A O   1 
ATOM 2977 C CB  . LEU C 3 216 ? 387.637 336.638 470.828 1.00 50.35  ? 216 LEU A CB  1 
ATOM 2978 C CG  . LEU C 3 216 ? 387.071 336.997 469.462 1.00 50.35  ? 216 LEU A CG  1 
ATOM 2979 C CD1 . LEU C 3 216 ? 387.145 338.483 469.286 1.00 50.35  ? 216 LEU A CD1 1 
ATOM 2980 C CD2 . LEU C 3 216 ? 387.836 336.310 468.369 1.00 50.35  ? 216 LEU A CD2 1 
ATOM 2981 N N   . TYR C 3 217 ? 388.810 334.223 472.692 1.00 51.93  ? 217 TYR A N   1 
ATOM 2982 C CA  . TYR C 3 217 ? 389.702 333.814 473.770 1.00 51.93  ? 217 TYR A CA  1 
ATOM 2983 C C   . TYR C 3 217 ? 391.111 333.640 473.234 1.00 51.93  ? 217 TYR A C   1 
ATOM 2984 O O   . TYR C 3 217 ? 391.294 333.109 472.140 1.00 51.93  ? 217 TYR A O   1 
ATOM 2985 C CB  . TYR C 3 217 ? 389.244 332.507 474.404 1.00 51.93  ? 217 TYR A CB  1 
ATOM 2986 C CG  . TYR C 3 217 ? 387.951 332.633 475.137 1.00 51.93  ? 217 TYR A CG  1 
ATOM 2987 C CD1 . TYR C 3 217 ? 387.926 332.972 476.472 1.00 51.93  ? 217 TYR A CD1 1 
ATOM 2988 C CD2 . TYR C 3 217 ? 386.755 332.435 474.489 1.00 51.93  ? 217 TYR A CD2 1 
ATOM 2989 C CE1 . TYR C 3 217 ? 386.750 333.105 477.134 1.00 51.93  ? 217 TYR A CE1 1 
ATOM 2990 C CE2 . TYR C 3 217 ? 385.578 332.565 475.144 1.00 51.93  ? 217 TYR A CE2 1 
ATOM 2991 C CZ  . TYR C 3 217 ? 385.582 332.901 476.462 1.00 51.93  ? 217 TYR A CZ  1 
ATOM 2992 O OH  . TYR C 3 217 ? 384.396 333.041 477.110 1.00 51.93  ? 217 TYR A OH  1 
ATOM 2993 N N   . MET C 3 218 ? 392.104 334.075 474.006 1.00 53.33  ? 218 MET A N   1 
ATOM 2994 C CA  . MET C 3 218 ? 393.496 334.071 473.574 1.00 53.33  ? 218 MET A CA  1 
ATOM 2995 C C   . MET C 3 218 ? 394.364 333.375 474.607 1.00 53.33  ? 218 MET A C   1 
ATOM 2996 O O   . MET C 3 218 ? 394.114 333.504 475.804 1.00 53.33  ? 218 MET A O   1 
ATOM 2997 C CB  . MET C 3 218 ? 394.006 335.490 473.369 1.00 53.33  ? 218 MET A CB  1 
ATOM 2998 C CG  . MET C 3 218 ? 393.772 336.069 471.997 1.00 53.33  ? 218 MET A CG  1 
ATOM 2999 S SD  . MET C 3 218 ? 392.081 336.613 471.709 1.00 53.33  ? 218 MET A SD  1 
ATOM 3000 C CE  . MET C 3 218 ? 391.972 338.067 472.732 1.00 53.33  ? 218 MET A CE  1 
ATOM 3001 N N   . ARG C 3 219 ? 395.390 332.657 474.148 1.00 50.87  ? 219 ARG A N   1 
ATOM 3002 C CA  . ARG C 3 219 ? 396.353 332.014 475.036 1.00 50.87  ? 219 ARG A CA  1 
ATOM 3003 C C   . ARG C 3 219 ? 397.607 331.657 474.253 1.00 50.87  ? 219 ARG A C   1 
ATOM 3004 O O   . ARG C 3 219 ? 397.595 331.624 473.025 1.00 50.87  ? 219 ARG A O   1 
ATOM 3005 C CB  . ARG C 3 219 ? 395.778 330.754 475.680 1.00 50.87  ? 219 ARG A CB  1 
ATOM 3006 C CG  . ARG C 3 219 ? 395.648 329.612 474.726 1.00 50.87  ? 219 ARG A CG  1 
ATOM 3007 C CD  . ARG C 3 219 ? 395.041 328.414 475.375 1.00 50.87  ? 219 ARG A CD  1 
ATOM 3008 N NE  . ARG C 3 219 ? 394.969 327.302 474.443 1.00 50.87  ? 219 ARG A NE  1 
ATOM 3009 C CZ  . ARG C 3 219 ? 395.244 326.051 474.765 1.00 50.87  ? 219 ARG A CZ  1 
ATOM 3010 N NH1 . ARG C 3 219 ? 395.591 325.757 476.000 1.00 50.87  ? 219 ARG A NH1 1 
ATOM 3011 N NH2 . ARG C 3 219 ? 395.154 325.098 473.857 1.00 50.87  ? 219 ARG A NH2 1 
ATOM 3012 N N   . HIS C 3 220 ? 398.693 331.398 474.977 1.00 54.81  ? 220 HIS A N   1 
ATOM 3013 C CA  . HIS C 3 220 ? 399.878 330.806 474.375 1.00 54.81  ? 220 HIS A CA  1 
ATOM 3014 C C   . HIS C 3 220 ? 399.656 329.317 474.167 1.00 54.81  ? 220 HIS A C   1 
ATOM 3015 O O   . HIS C 3 220 ? 398.807 328.708 474.811 1.00 54.81  ? 220 HIS A O   1 
ATOM 3016 C CB  . HIS C 3 220 ? 401.107 330.990 475.261 1.00 54.81  ? 220 HIS A CB  1 
ATOM 3017 C CG  . HIS C 3 220 ? 401.427 332.412 475.592 1.00 54.81  ? 220 HIS A CG  1 
ATOM 3018 N ND1 . HIS C 3 220 ? 400.948 333.038 476.719 1.00 54.81  ? 220 HIS A ND1 1 
ATOM 3019 C CD2 . HIS C 3 220 ? 402.213 333.316 474.966 1.00 54.81  ? 220 HIS A CD2 1 
ATOM 3020 C CE1 . HIS C 3 220 ? 401.409 334.273 476.763 1.00 54.81  ? 220 HIS A CE1 1 
ATOM 3021 N NE2 . HIS C 3 220 ? 402.176 334.468 475.710 1.00 54.81  ? 220 HIS A NE2 1 
ATOM 3022 N N   . VAL C 3 221 ? 400.441 328.708 473.279 1.00 55.02  ? 221 VAL A N   1 
ATOM 3023 C CA  . VAL C 3 221 ? 400.339 327.258 473.146 1.00 55.02  ? 221 VAL A CA  1 
ATOM 3024 C C   . VAL C 3 221 ? 401.641 326.581 473.555 1.00 55.02  ? 221 VAL A C   1 
ATOM 3025 O O   . VAL C 3 221 ? 401.684 325.360 473.721 1.00 55.02  ? 221 VAL A O   1 
ATOM 3026 C CB  . VAL C 3 221 ? 399.932 326.829 471.726 1.00 55.02  ? 221 VAL A CB  1 
ATOM 3027 C CG1 . VAL C 3 221 ? 398.800 327.654 471.217 1.00 55.02  ? 221 VAL A CG1 1 
ATOM 3028 C CG2 . VAL C 3 221 ? 401.083 326.906 470.800 1.00 55.02  ? 221 VAL A CG2 1 
ATOM 3029 N N   . ASN C 3 222 ? 402.705 327.352 473.740 1.00 61.88  ? 222 ASN A N   1 
ATOM 3030 C CA  . ASN C 3 222 ? 403.978 326.816 474.201 1.00 61.88  ? 222 ASN A CA  1 
ATOM 3031 C C   . ASN C 3 222 ? 403.984 326.759 475.719 1.00 61.88  ? 222 ASN A C   1 
ATOM 3032 O O   . ASN C 3 222 ? 403.462 327.659 476.380 1.00 61.88  ? 222 ASN A O   1 
ATOM 3033 C CB  . ASN C 3 222 ? 405.146 327.672 473.728 1.00 61.88  ? 222 ASN A CB  1 
ATOM 3034 C CG  . ASN C 3 222 ? 405.052 328.026 472.287 1.00 61.88  ? 222 ASN A CG  1 
ATOM 3035 O OD1 . ASN C 3 222 ? 404.602 329.106 471.941 1.00 61.88  ? 222 ASN A OD1 1 
ATOM 3036 N ND2 . ASN C 3 222 ? 405.500 327.136 471.427 1.00 61.88  ? 222 ASN A ND2 1 
ATOM 3037 N N   . GLU C 3 223 ? 404.581 325.712 476.267 1.00 72.93  ? 223 GLU A N   1 
ATOM 3038 C CA  . GLU C 3 223 ? 404.786 325.622 477.701 1.00 72.93  ? 223 GLU A CA  1 
ATOM 3039 C C   . GLU C 3 223 ? 405.922 326.538 478.120 1.00 72.93  ? 223 GLU A C   1 
ATOM 3040 O O   . GLU C 3 223 ? 406.792 326.870 477.315 1.00 72.93  ? 223 GLU A O   1 
ATOM 3041 C CB  . GLU C 3 223 ? 405.085 324.180 478.103 1.00 72.93  ? 223 GLU A CB  1 
ATOM 3042 C CG  . GLU C 3 223 ? 403.863 323.388 478.536 1.00 72.93  ? 223 GLU A CG  1 
ATOM 3043 C CD  . GLU C 3 223 ? 403.017 322.865 477.389 1.00 72.93  ? 223 GLU A CD  1 
ATOM 3044 O OE1 . GLU C 3 223 ? 402.093 322.074 477.658 1.00 72.93  ? 223 GLU A OE1 1 
ATOM 3045 O OE2 . GLU C 3 223 ? 403.270 323.215 476.221 1.00 72.93  ? 223 GLU A OE2 1 
ATOM 3046 N N   . ALA C 3 224 ? 405.894 326.963 479.377 1.00 76.11  ? 224 ALA A N   1 
ATOM 3047 C CA  . ALA C 3 224 ? 406.906 327.874 479.883 1.00 76.11  ? 224 ALA A CA  1 
ATOM 3048 C C   . ALA C 3 224 ? 408.231 327.150 480.015 1.00 76.11  ? 224 ALA A C   1 
ATOM 3049 O O   . ALA C 3 224 ? 408.323 326.117 480.680 1.00 76.11  ? 224 ALA A O   1 
ATOM 3050 C CB  . ALA C 3 224 ? 406.486 328.447 481.231 1.00 76.11  ? 224 ALA A CB  1 
ATOM 3051 N N   . GLY C 3 225 ? 409.258 327.684 479.370 1.00 79.75  ? 225 GLY A N   1 
ATOM 3052 C CA  . GLY C 3 225 ? 410.510 326.968 479.345 1.00 79.75  ? 225 GLY A CA  1 
ATOM 3053 C C   . GLY C 3 225 ? 411.463 327.327 480.458 1.00 79.75  ? 225 GLY A C   1 
ATOM 3054 O O   . GLY C 3 225 ? 411.848 326.463 481.246 1.00 79.75  ? 225 GLY A O   1 
ATOM 3055 N N   . GLN C 3 226 ? 411.842 328.595 480.551 1.00 82.01  ? 226 GLN A N   1 
ATOM 3056 C CA  . GLN C 3 226 ? 412.772 329.030 481.581 1.00 82.01  ? 226 GLN A CA  1 
ATOM 3057 C C   . GLN C 3 226 ? 412.371 330.313 482.276 1.00 82.01  ? 226 GLN A C   1 
ATOM 3058 O O   . GLN C 3 226 ? 412.735 330.495 483.442 1.00 82.01  ? 226 GLN A O   1 
ATOM 3059 C CB  . GLN C 3 226 ? 414.175 329.213 480.994 1.00 82.01  ? 226 GLN A CB  1 
ATOM 3060 C CG  . GLN C 3 226 ? 414.941 327.925 480.828 1.00 82.01  ? 226 GLN A CG  1 
ATOM 3061 C CD  . GLN C 3 226 ? 414.981 327.109 482.093 1.00 82.01  ? 226 GLN A CD  1 
ATOM 3062 O OE1 . GLN C 3 226 ? 414.550 325.960 482.117 1.00 82.01  ? 226 GLN A OE1 1 
ATOM 3063 N NE2 . GLN C 3 226 ? 415.509 327.696 483.155 1.00 82.01  ? 226 GLN A NE2 1 
ATOM 3064 N N   . GLY C 3 227 ? 411.636 331.197 481.619 1.00 77.96  ? 227 GLY A N   1 
ATOM 3065 C CA  . GLY C 3 227 ? 411.253 332.451 482.208 1.00 77.96  ? 227 GLY A CA  1 
ATOM 3066 C C   . GLY C 3 227 ? 409.880 332.875 481.749 1.00 77.96  ? 227 GLY A C   1 
ATOM 3067 O O   . GLY C 3 227 ? 409.401 332.463 480.690 1.00 77.96  ? 227 GLY A O   1 
ATOM 3068 N N   . PRO C 3 228 ? 409.210 333.694 482.549 1.00 72.91  ? 228 PRO A N   1 
ATOM 3069 C CA  . PRO C 3 228 ? 407.862 334.127 482.189 1.00 72.91  ? 228 PRO A CA  1 
ATOM 3070 C C   . PRO C 3 228 ? 407.888 335.113 481.038 1.00 72.91  ? 228 PRO A C   1 
ATOM 3071 O O   . PRO C 3 228 ? 408.852 335.851 480.840 1.00 72.91  ? 228 PRO A O   1 
ATOM 3072 C CB  . PRO C 3 228 ? 407.343 334.782 483.473 1.00 72.91  ? 228 PRO A CB  1 
ATOM 3073 C CG  . PRO C 3 228 ? 408.292 334.367 484.545 1.00 72.91  ? 228 PRO A CG  1 
ATOM 3074 C CD  . PRO C 3 228 ? 409.600 334.176 483.878 1.00 72.91  ? 228 PRO A CD  1 
ATOM 3075 N N   . ILE C 3 229 ? 406.812 335.097 480.261 1.00 65.20  ? 229 ILE A N   1 
ATOM 3076 C CA  . ILE C 3 229 ? 406.647 335.950 479.093 1.00 65.20  ? 229 ILE A CA  1 
ATOM 3077 C C   . ILE C 3 229 ? 405.195 336.388 479.078 1.00 65.20  ? 229 ILE A C   1 
ATOM 3078 O O   . ILE C 3 229 ? 404.296 335.545 479.118 1.00 65.20  ? 229 ILE A O   1 
ATOM 3079 C CB  . ILE C 3 229 ? 407.012 335.216 477.791 1.00 65.20  ? 229 ILE A CB  1 
ATOM 3080 C CG1 . ILE C 3 229 ? 408.519 335.219 477.582 1.00 65.20  ? 229 ILE A CG1 1 
ATOM 3081 C CG2 . ILE C 3 229 ? 406.337 335.818 476.597 1.00 65.20  ? 229 ILE A CG2 1 
ATOM 3082 C CD1 . ILE C 3 229 ? 408.960 334.399 476.408 1.00 65.20  ? 229 ILE A CD1 1 
ATOM 3083 N N   . LYS C 3 230 ? 404.953 337.689 479.071 1.00 60.75  ? 230 LYS A N   1 
ATOM 3084 C CA  . LYS C 3 230 ? 403.586 338.174 479.052 1.00 60.75  ? 230 LYS A CA  1 
ATOM 3085 C C   . LYS C 3 230 ? 403.321 338.942 477.768 1.00 60.75  ? 230 LYS A C   1 
ATOM 3086 O O   . LYS C 3 230 ? 404.211 339.584 477.209 1.00 60.75  ? 230 LYS A O   1 
ATOM 3087 C CB  . LYS C 3 230 ? 403.279 339.022 480.282 1.00 60.75  ? 230 LYS A CB  1 
ATOM 3088 C CG  . LYS C 3 230 ? 403.723 340.439 480.259 1.00 60.75  ? 230 LYS A CG  1 
ATOM 3089 C CD  . LYS C 3 230 ? 402.968 341.221 481.303 1.00 60.75  ? 230 LYS A CD  1 
ATOM 3090 C CE  . LYS C 3 230 ? 401.484 341.115 481.071 1.00 60.75  ? 230 LYS A CE  1 
ATOM 3091 N NZ  . LYS C 3 230 ? 400.703 341.882 482.060 1.00 60.75  ? 230 LYS A NZ  1 
ATOM 3092 N N   . SER C 3 231 ? 402.093 338.827 477.281 1.00 56.83  ? 231 SER A N   1 
ATOM 3093 C CA  . SER C 3 231 ? 401.748 339.297 475.956 1.00 56.83  ? 231 SER A CA  1 
ATOM 3094 C C   . SER C 3 231 ? 400.484 340.121 476.034 1.00 56.83  ? 231 SER A C   1 
ATOM 3095 O O   . SER C 3 231 ? 399.603 339.840 476.839 1.00 56.83  ? 231 SER A O   1 
ATOM 3096 C CB  . SER C 3 231 ? 401.532 338.141 474.997 1.00 56.83  ? 231 SER A CB  1 
ATOM 3097 O OG  . SER C 3 231 ? 402.676 337.324 474.939 1.00 56.83  ? 231 SER A OG  1 
ATOM 3098 N N   . THR C 3 232 ? 400.407 341.140 475.194 1.00 56.24  ? 232 THR A N   1 
ATOM 3099 C CA  . THR C 3 232 ? 399.235 341.986 475.072 1.00 56.24  ? 232 THR A CA  1 
ATOM 3100 C C   . THR C 3 232 ? 398.627 341.818 473.691 1.00 56.24  ? 232 THR A C   1 
ATOM 3101 O O   . THR C 3 232 ? 399.289 341.400 472.745 1.00 56.24  ? 232 THR A O   1 
ATOM 3102 C CB  . THR C 3 232 ? 399.595 343.451 475.309 1.00 56.24  ? 232 THR A CB  1 
ATOM 3103 O OG1 . THR C 3 232 ? 400.385 343.917 474.215 1.00 56.24  ? 232 THR A OG1 1 
ATOM 3104 C CG2 . THR C 3 232 ? 400.387 343.607 476.584 1.00 56.24  ? 232 THR A CG2 1 
ATOM 3105 N N   . VAL C 3 233 ? 397.354 342.166 473.574 1.00 54.13  ? 233 VAL A N   1 
ATOM 3106 C CA  . VAL C 3 233 ? 396.633 342.010 472.317 1.00 54.13  ? 233 VAL A CA  1 
ATOM 3107 C C   . VAL C 3 233 ? 395.740 343.228 472.132 1.00 54.13  ? 233 VAL A C   1 
ATOM 3108 O O   . VAL C 3 233 ? 395.149 343.727 473.091 1.00 54.13  ? 233 VAL A O   1 
ATOM 3109 C CB  . VAL C 3 233 ? 395.853 340.674 472.290 1.00 54.13  ? 233 VAL A CB  1 
ATOM 3110 C CG1 . VAL C 3 233 ? 394.962 340.537 473.485 1.00 54.13  ? 233 VAL A CG1 1 
ATOM 3111 C CG2 . VAL C 3 233 ? 395.055 340.502 471.019 1.00 54.13  ? 233 VAL A CG2 1 
ATOM 3112 N N   . ARG C 3 234 ? 395.702 343.757 470.917 1.00 53.69  ? 234 ARG A N   1 
ATOM 3113 C CA  . ARG C 3 234 ? 394.832 344.869 470.563 1.00 53.69  ? 234 ARG A CA  1 
ATOM 3114 C C   . ARG C 3 234 ? 393.944 344.385 469.429 1.00 53.69  ? 234 ARG A C   1 
ATOM 3115 O O   . ARG C 3 234 ? 394.439 343.961 468.386 1.00 53.69  ? 234 ARG A O   1 
ATOM 3116 C CB  . ARG C 3 234 ? 395.633 346.092 470.156 1.00 53.69  ? 234 ARG A CB  1 
ATOM 3117 C CG  . ARG C 3 234 ? 396.632 346.545 471.178 1.00 53.69  ? 234 ARG A CG  1 
ATOM 3118 C CD  . ARG C 3 234 ? 397.700 347.394 470.536 1.00 53.69  ? 234 ARG A CD  1 
ATOM 3119 N NE  . ARG C 3 234 ? 398.894 347.443 471.363 1.00 53.69  ? 234 ARG A NE  1 
ATOM 3120 C CZ  . ARG C 3 234 ? 399.299 348.525 472.010 1.00 53.69  ? 234 ARG A CZ  1 
ATOM 3121 N NH1 . ARG C 3 234 ? 398.612 349.647 471.905 1.00 53.69  ? 234 ARG A NH1 1 
ATOM 3122 N NH2 . ARG C 3 234 ? 400.393 348.489 472.752 1.00 53.69  ? 234 ARG A NH2 1 
ATOM 3123 N N   . ILE C 3 235 ? 392.643 344.430 469.635 1.00 49.79  ? 235 ILE A N   1 
ATOM 3124 C CA  . ILE C 3 235 ? 391.701 343.915 468.656 1.00 49.79  ? 235 ILE A CA  1 
ATOM 3125 C C   . ILE C 3 235 ? 391.163 345.070 467.833 1.00 49.79  ? 235 ILE A C   1 
ATOM 3126 O O   . ILE C 3 235 ? 390.681 346.061 468.382 1.00 49.79  ? 235 ILE A O   1 
ATOM 3127 C CB  . ILE C 3 235 ? 390.568 343.159 469.356 1.00 49.79  ? 235 ILE A CB  1 
ATOM 3128 C CG1 . ILE C 3 235 ? 391.155 342.163 470.337 1.00 49.79  ? 235 ILE A CG1 1 
ATOM 3129 C CG2 . ILE C 3 235 ? 389.709 342.462 468.359 1.00 49.79  ? 235 ILE A CG2 1 
ATOM 3130 C CD1 . ILE C 3 235 ? 390.143 341.507 471.173 1.00 49.79  ? 235 ILE A CD1 1 
ATOM 3131 N N   . TYR C 3 236 ? 391.235 344.949 466.519 1.00 50.34  ? 236 TYR A N   1 
ATOM 3132 C CA  . TYR C 3 236 ? 390.715 345.983 465.644 1.00 50.34  ? 236 TYR A CA  1 
ATOM 3133 C C   . TYR C 3 236 ? 389.416 345.523 465.004 1.00 50.34  ? 236 TYR A C   1 
ATOM 3134 O O   . TYR C 3 236 ? 389.223 344.349 464.709 1.00 50.34  ? 236 TYR A O   1 
ATOM 3135 C CB  . TYR C 3 236 ? 391.745 346.360 464.584 1.00 50.34  ? 236 TYR A CB  1 
ATOM 3136 C CG  . TYR C 3 236 ? 392.786 347.296 465.125 1.00 50.34  ? 236 TYR A CG  1 
ATOM 3137 C CD1 . TYR C 3 236 ? 393.871 346.820 465.830 1.00 50.34  ? 236 TYR A CD1 1 
ATOM 3138 C CD2 . TYR C 3 236 ? 392.662 348.655 464.962 1.00 50.34  ? 236 TYR A CD2 1 
ATOM 3139 C CE1 . TYR C 3 236 ? 394.807 347.668 466.343 1.00 50.34  ? 236 TYR A CE1 1 
ATOM 3140 C CE2 . TYR C 3 236 ? 393.594 349.511 465.467 1.00 50.34  ? 236 TYR A CE2 1 
ATOM 3141 C CZ  . TYR C 3 236 ? 394.662 349.015 466.157 1.00 50.34  ? 236 TYR A CZ  1 
ATOM 3142 O OH  . TYR C 3 236 ? 395.591 349.884 466.657 1.00 50.34  ? 236 TYR A OH  1 
ATOM 3143 N N   . PHE C 3 237 ? 388.528 346.477 464.781 1.00 54.03  ? 237 PHE A N   1 
ATOM 3144 C CA  . PHE C 3 237 ? 387.126 346.211 464.517 1.00 54.03  ? 237 PHE A CA  1 
ATOM 3145 C C   . PHE C 3 237 ? 386.722 346.997 463.287 1.00 54.03  ? 237 PHE A C   1 
ATOM 3146 O O   . PHE C 3 237 ? 386.933 348.209 463.237 1.00 54.03  ? 237 PHE A O   1 
ATOM 3147 C CB  . PHE C 3 237 ? 386.306 346.637 465.734 1.00 54.03  ? 237 PHE A CB  1 
ATOM 3148 C CG  . PHE C 3 237 ? 384.860 346.266 465.687 1.00 54.03  ? 237 PHE A CG  1 
ATOM 3149 C CD1 . PHE C 3 237 ? 383.927 347.115 465.115 1.00 54.03  ? 237 PHE A CD1 1 
ATOM 3150 C CD2 . PHE C 3 237 ? 384.420 345.111 466.285 1.00 54.03  ? 237 PHE A CD2 1 
ATOM 3151 C CE1 . PHE C 3 237 ? 382.600 346.790 465.095 1.00 54.03  ? 237 PHE A CE1 1 
ATOM 3152 C CE2 . PHE C 3 237 ? 383.090 344.788 466.277 1.00 54.03  ? 237 PHE A CE2 1 
ATOM 3153 C CZ  . PHE C 3 237 ? 382.181 345.631 465.683 1.00 54.03  ? 237 PHE A CZ  1 
ATOM 3154 N N   . LYS C 3 238 ? 386.129 346.334 462.319 1.00 56.98  ? 238 LYS A N   1 
ATOM 3155 C CA  . LYS C 3 238 ? 385.779 347.032 461.093 1.00 56.98  ? 238 LYS A CA  1 
ATOM 3156 C C   . LYS C 3 238 ? 384.470 346.503 460.531 1.00 56.98  ? 238 LYS A C   1 
ATOM 3157 O O   . LYS C 3 238 ? 384.431 345.373 460.038 1.00 56.98  ? 238 LYS A O   1 
ATOM 3158 C CB  . LYS C 3 238 ? 386.899 346.868 460.079 1.00 56.98  ? 238 LYS A CB  1 
ATOM 3159 C CG  . LYS C 3 238 ? 386.690 347.552 458.764 1.00 56.98  ? 238 LYS A CG  1 
ATOM 3160 C CD  . LYS C 3 238 ? 388.008 347.583 458.024 1.00 56.98  ? 238 LYS A CD  1 
ATOM 3161 C CE  . LYS C 3 238 ? 387.931 348.339 456.730 1.00 56.98  ? 238 LYS A CE  1 
ATOM 3162 N NZ  . LYS C 3 238 ? 387.260 347.528 455.695 1.00 56.98  ? 238 LYS A NZ  1 
ATOM 3163 N N   . PRO C 3 239 ? 383.380 347.259 460.609 1.00 54.49  ? 239 PRO A N   1 
ATOM 3164 C CA  . PRO C 3 239 ? 382.139 346.824 459.975 1.00 54.49  ? 239 PRO A CA  1 
ATOM 3165 C C   . PRO C 3 239 ? 382.263 346.864 458.467 1.00 54.49  ? 239 PRO A C   1 
ATOM 3166 O O   . PRO C 3 239 ? 382.831 347.786 457.892 1.00 54.49  ? 239 PRO A O   1 
ATOM 3167 C CB  . PRO C 3 239 ? 381.115 347.845 460.467 1.00 54.49  ? 239 PRO A CB  1 
ATOM 3168 C CG  . PRO C 3 239 ? 381.718 348.455 461.645 1.00 54.49  ? 239 PRO A CG  1 
ATOM 3169 C CD  . PRO C 3 239 ? 383.175 348.473 461.404 1.00 54.49  ? 239 PRO A CD  1 
ATOM 3170 N N   . LYS C 3 240 ? 381.720 345.843 457.822 1.00 56.63  ? 240 LYS A N   1 
ATOM 3171 C CA  . LYS C 3 240 ? 381.852 345.730 456.381 1.00 56.63  ? 240 LYS A CA  1 
ATOM 3172 C C   . LYS C 3 240 ? 380.490 345.493 455.767 1.00 56.63  ? 240 LYS A C   1 
ATOM 3173 O O   . LYS C 3 240 ? 379.700 344.718 456.305 1.00 56.63  ? 240 LYS A O   1 
ATOM 3174 C CB  . LYS C 3 240 ? 382.778 344.587 455.991 1.00 56.63  ? 240 LYS A CB  1 
ATOM 3175 C CG  . LYS C 3 240 ? 384.232 344.904 456.066 1.00 56.63  ? 240 LYS A CG  1 
ATOM 3176 C CD  . LYS C 3 240 ? 385.000 344.093 455.047 1.00 56.63  ? 240 LYS A CD  1 
ATOM 3177 C CE  . LYS C 3 240 ? 384.681 342.606 455.148 1.00 56.63  ? 240 LYS A CE  1 
ATOM 3178 N NZ  . LYS C 3 240 ? 385.412 341.789 454.137 1.00 56.63  ? 240 LYS A NZ  1 
ATOM 3179 N N   . HIS C 3 241 ? 380.246 346.150 454.633 1.00 56.21  ? 241 HIS A N   1 
ATOM 3180 C CA  . HIS C 3 241 ? 379.022 346.034 453.845 1.00 56.21  ? 241 HIS A CA  1 
ATOM 3181 C C   . HIS C 3 241 ? 377.792 346.355 454.695 1.00 56.21  ? 241 HIS A C   1 
ATOM 3182 O O   . HIS C 3 241 ? 376.925 345.518 454.935 1.00 56.21  ? 241 HIS A O   1 
ATOM 3183 C CB  . HIS C 3 241 ? 378.930 344.655 453.188 1.00 56.21  ? 241 HIS A CB  1 
ATOM 3184 C CG  . HIS C 3 241 ? 380.179 344.250 452.467 1.00 56.21  ? 241 HIS A CG  1 
ATOM 3185 N ND1 . HIS C 3 241 ? 380.660 342.960 452.475 1.00 56.21  ? 241 HIS A ND1 1 
ATOM 3186 C CD2 . HIS C 3 241 ? 381.046 344.966 451.716 1.00 56.21  ? 241 HIS A CD2 1 
ATOM 3187 C CE1 . HIS C 3 241 ? 381.772 342.901 451.765 1.00 56.21  ? 241 HIS A CE1 1 
ATOM 3188 N NE2 . HIS C 3 241 ? 382.028 344.105 451.293 1.00 56.21  ? 241 HIS A NE2 1 
ATOM 3189 N N   . VAL C 3 242 ? 377.745 347.599 455.151 1.00 54.06  ? 242 VAL A N   1 
ATOM 3190 C CA  . VAL C 3 242 ? 376.801 348.021 456.174 1.00 54.06  ? 242 VAL A CA  1 
ATOM 3191 C C   . VAL C 3 242 ? 375.493 348.442 455.530 1.00 54.06  ? 242 VAL A C   1 
ATOM 3192 O O   . VAL C 3 242 ? 375.480 349.169 454.533 1.00 54.06  ? 242 VAL A O   1 
ATOM 3193 C CB  . VAL C 3 242 ? 377.396 349.170 457.000 1.00 54.06  ? 242 VAL A CB  1 
ATOM 3194 C CG1 . VAL C 3 242 ? 376.636 349.345 458.271 1.00 54.06  ? 242 VAL A CG1 1 
ATOM 3195 C CG2 . VAL C 3 242 ? 378.830 348.905 457.298 1.00 54.06  ? 242 VAL A CG2 1 
ATOM 3196 N N   . LYS C 3 243 ? 374.386 347.977 456.099 1.00 54.26  ? 243 LYS A N   1 
ATOM 3197 C CA  . LYS C 3 243 ? 373.059 348.485 455.800 1.00 54.26  ? 243 LYS A CA  1 
ATOM 3198 C C   . LYS C 3 243 ? 372.478 349.050 457.080 1.00 54.26  ? 243 LYS A C   1 
ATOM 3199 O O   . LYS C 3 243 ? 372.681 348.484 458.152 1.00 54.26  ? 243 LYS A O   1 
ATOM 3200 C CB  . LYS C 3 243 ? 372.148 347.406 455.265 1.00 54.26  ? 243 LYS A CB  1 
ATOM 3201 C CG  . LYS C 3 243 ? 372.755 346.573 454.187 1.00 54.26  ? 243 LYS A CG  1 
ATOM 3202 C CD  . LYS C 3 243 ? 371.874 345.399 453.873 1.00 54.26  ? 243 LYS A CD  1 
ATOM 3203 C CE  . LYS C 3 243 ? 372.418 344.612 452.712 1.00 54.26  ? 243 LYS A CE  1 
ATOM 3204 N NZ  . LYS C 3 243 ? 372.334 345.381 451.447 1.00 54.26  ? 243 LYS A NZ  1 
ATOM 3205 N N   . ALA C 3 244 ? 371.768 350.165 456.978 1.00 53.23  ? 244 ALA A N   1 
ATOM 3206 C CA  . ALA C 3 244 ? 371.221 350.821 458.150 1.00 53.23  ? 244 ALA A CA  1 
ATOM 3207 C C   . ALA C 3 244 ? 369.801 351.292 457.887 1.00 53.23  ? 244 ALA A C   1 
ATOM 3208 O O   . ALA C 3 244 ? 369.442 351.648 456.767 1.00 53.23  ? 244 ALA A O   1 
ATOM 3209 C CB  . ALA C 3 244 ? 372.091 351.997 458.564 1.00 53.23  ? 244 ALA A CB  1 
ATOM 3210 N N   . TRP C 3 245 ? 368.997 351.303 458.946 1.00 53.68  ? 245 TRP A N   1 
ATOM 3211 C CA  . TRP C 3 245 ? 367.579 351.605 458.851 1.00 53.68  ? 245 TRP A CA  1 
ATOM 3212 C C   . TRP C 3 245 ? 367.176 352.454 460.041 1.00 53.68  ? 245 TRP A C   1 
ATOM 3213 O O   . TRP C 3 245 ? 367.777 352.348 461.108 1.00 53.68  ? 245 TRP A O   1 
ATOM 3214 C CB  . TRP C 3 245 ? 366.724 350.340 458.857 1.00 53.68  ? 245 TRP A CB  1 
ATOM 3215 C CG  . TRP C 3 245 ? 366.846 349.480 457.670 1.00 53.68  ? 245 TRP A CG  1 
ATOM 3216 C CD1 . TRP C 3 245 ? 366.185 349.611 456.507 1.00 53.68  ? 245 TRP A CD1 1 
ATOM 3217 C CD2 . TRP C 3 245 ? 367.657 348.316 457.544 1.00 53.68  ? 245 TRP A CD2 1 
ATOM 3218 N NE1 . TRP C 3 245 ? 366.541 348.616 455.645 1.00 53.68  ? 245 TRP A NE1 1 
ATOM 3219 C CE2 . TRP C 3 245 ? 367.448 347.804 456.265 1.00 53.68  ? 245 TRP A CE2 1 
ATOM 3220 C CE3 . TRP C 3 245 ? 368.551 347.663 458.389 1.00 53.68  ? 245 TRP A CE3 1 
ATOM 3221 C CZ2 . TRP C 3 245 ? 368.095 346.677 455.809 1.00 53.68  ? 245 TRP A CZ2 1 
ATOM 3222 C CZ3 . TRP C 3 245 ? 369.185 346.555 457.936 1.00 53.68  ? 245 TRP A CZ3 1 
ATOM 3223 C CH2 . TRP C 3 245 ? 368.959 346.068 456.661 1.00 53.68  ? 245 TRP A CH2 1 
ATOM 3224 N N   . VAL C 3 246 ? 366.118 353.244 459.855 1.00 51.69  ? 246 VAL A N   1 
ATOM 3225 C CA  . VAL C 3 246 ? 365.427 354.019 460.890 1.00 51.69  ? 246 VAL A CA  1 
ATOM 3226 C C   . VAL C 3 246 ? 366.381 354.936 461.646 1.00 51.69  ? 246 VAL A C   1 
ATOM 3227 O O   . VAL C 3 246 ? 366.896 354.552 462.704 1.00 51.69  ? 246 VAL A O   1 
ATOM 3228 C CB  . VAL C 3 246 ? 364.655 353.100 461.847 1.00 51.69  ? 246 VAL A CB  1 
ATOM 3229 C CG1 . VAL C 3 246 ? 363.758 353.900 462.751 1.00 51.69  ? 246 VAL A CG1 1 
ATOM 3230 C CG2 . VAL C 3 246 ? 363.805 352.156 461.058 1.00 51.69  ? 246 VAL A CG2 1 
ATOM 3231 N N   . PRO C 3 247 ? 366.725 356.099 461.094 1.00 50.08  ? 247 PRO A N   1 
ATOM 3232 C CA  . PRO C 3 247 ? 367.626 357.014 461.796 1.00 50.08  ? 247 PRO A CA  1 
ATOM 3233 C C   . PRO C 3 247 ? 367.013 357.555 463.076 1.00 50.08  ? 247 PRO A C   1 
ATOM 3234 O O   . PRO C 3 247 ? 365.814 357.436 463.322 1.00 50.08  ? 247 PRO A O   1 
ATOM 3235 C CB  . PRO C 3 247 ? 367.858 358.128 460.781 1.00 50.08  ? 247 PRO A CB  1 
ATOM 3236 C CG  . PRO C 3 247 ? 366.694 358.094 459.917 1.00 50.08  ? 247 PRO A CG  1 
ATOM 3237 C CD  . PRO C 3 247 ? 366.178 356.701 459.873 1.00 50.08  ? 247 PRO A CD  1 
ATOM 3238 N N   . ARG C 3 248 ? 367.856 358.175 463.883 1.00 51.04  ? 248 ARG A N   1 
ATOM 3239 C CA  . ARG C 3 248 ? 367.617 358.386 465.296 1.00 51.04  ? 248 ARG A CA  1 
ATOM 3240 C C   . ARG C 3 248 ? 368.472 359.558 465.751 1.00 51.04  ? 248 ARG A C   1 
ATOM 3241 O O   . ARG C 3 248 ? 369.558 359.760 465.208 1.00 51.04  ? 248 ARG A O   1 
ATOM 3242 C CB  . ARG C 3 248 ? 367.984 357.092 466.033 1.00 51.04  ? 248 ARG A CB  1 
ATOM 3243 C CG  . ARG C 3 248 ? 367.821 357.044 467.506 1.00 51.04  ? 248 ARG A CG  1 
ATOM 3244 C CD  . ARG C 3 248 ? 367.869 355.624 467.959 1.00 51.04  ? 248 ARG A CD  1 
ATOM 3245 N NE  . ARG C 3 248 ? 366.610 354.935 467.742 1.00 51.04  ? 248 ARG A NE  1 
ATOM 3246 C CZ  . ARG C 3 248 ? 365.668 354.808 468.665 1.00 51.04  ? 248 ARG A CZ  1 
ATOM 3247 N NH1 . ARG C 3 248 ? 365.843 355.318 469.872 1.00 51.04  ? 248 ARG A NH1 1 
ATOM 3248 N NH2 . ARG C 3 248 ? 364.552 354.164 468.383 1.00 51.04  ? 248 ARG A NH2 1 
ATOM 3249 N N   . PRO C 3 249 ? 367.998 360.382 466.685 1.00 51.53  ? 249 PRO A N   1 
ATOM 3250 C CA  . PRO C 3 249 ? 368.761 361.566 467.076 1.00 51.53  ? 249 PRO A CA  1 
ATOM 3251 C C   . PRO C 3 249 ? 370.006 361.191 467.854 1.00 51.53  ? 249 PRO A C   1 
ATOM 3252 O O   . PRO C 3 249 ? 370.012 360.194 468.587 1.00 51.53  ? 249 PRO A O   1 
ATOM 3253 C CB  . PRO C 3 249 ? 367.773 362.345 467.950 1.00 51.53  ? 249 PRO A CB  1 
ATOM 3254 C CG  . PRO C 3 249 ? 366.812 361.362 468.393 1.00 51.53  ? 249 PRO A CG  1 
ATOM 3255 C CD  . PRO C 3 249 ? 366.655 360.418 467.277 1.00 51.53  ? 249 PRO A CD  1 
ATOM 3256 N N   . PRO C 3 250 ? 371.085 361.953 467.711 1.00 53.83  ? 250 PRO A N   1 
ATOM 3257 C CA  . PRO C 3 250 ? 372.336 361.576 468.360 1.00 53.83  ? 250 PRO A CA  1 
ATOM 3258 C C   . PRO C 3 250 ? 372.275 361.909 469.832 1.00 53.83  ? 250 PRO A C   1 
ATOM 3259 O O   . PRO C 3 250 ? 371.522 362.784 470.252 1.00 53.83  ? 250 PRO A O   1 
ATOM 3260 C CB  . PRO C 3 250 ? 373.382 362.431 467.641 1.00 53.83  ? 250 PRO A CB  1 
ATOM 3261 C CG  . PRO C 3 250 ? 372.647 363.156 466.568 1.00 53.83  ? 250 PRO A CG  1 
ATOM 3262 C CD  . PRO C 3 250 ? 371.236 363.218 466.994 1.00 53.83  ? 250 PRO A CD  1 
ATOM 3263 N N   . ARG C 3 251 ? 373.081 361.207 470.616 1.00 56.62  ? 251 ARG A N   1 
ATOM 3264 C CA  . ARG C 3 251 ? 372.985 361.311 472.060 1.00 56.62  ? 251 ARG A CA  1 
ATOM 3265 C C   . ARG C 3 251 ? 373.546 362.641 472.528 1.00 56.62  ? 251 ARG A C   1 
ATOM 3266 O O   . ARG C 3 251 ? 374.533 363.133 471.982 1.00 56.62  ? 251 ARG A O   1 
ATOM 3267 C CB  . ARG C 3 251 ? 373.727 360.169 472.732 1.00 56.62  ? 251 ARG A CB  1 
ATOM 3268 C CG  . ARG C 3 251 ? 373.393 360.066 474.185 1.00 56.62  ? 251 ARG A CG  1 
ATOM 3269 C CD  . ARG C 3 251 ? 374.119 358.958 474.811 1.00 56.62  ? 251 ARG A CD  1 
ATOM 3270 N NE  . ARG C 3 251 ? 373.810 358.801 476.219 1.00 56.62  ? 251 ARG A NE  1 
ATOM 3271 C CZ  . ARG C 3 251 ? 372.832 358.036 476.668 1.00 56.62  ? 251 ARG A CZ  1 
ATOM 3272 N NH1 . ARG C 3 251 ? 372.071 357.375 475.817 1.00 56.62  ? 251 ARG A NH1 1 
ATOM 3273 N NH2 . ARG C 3 251 ? 372.618 357.930 477.962 1.00 56.62  ? 251 ARG A NH2 1 
ATOM 3274 N N   . LEU C 3 252 ? 372.891 363.238 473.516 1.00 55.87  ? 252 LEU A N   1 
ATOM 3275 C CA  . LEU C 3 252 ? 373.347 364.471 474.127 1.00 55.87  ? 252 LEU A CA  1 
ATOM 3276 C C   . LEU C 3 252 ? 374.022 364.213 475.465 1.00 55.87  ? 252 LEU A C   1 
ATOM 3277 O O   . LEU C 3 252 ? 375.035 364.839 475.782 1.00 55.87  ? 252 LEU A O   1 
ATOM 3278 C CB  . LEU C 3 252 ? 372.166 365.419 474.286 1.00 55.87  ? 252 LEU A CB  1 
ATOM 3279 C CG  . LEU C 3 252 ? 372.216 366.532 475.318 1.00 55.87  ? 252 LEU A CG  1 
ATOM 3280 C CD1 . LEU C 3 252 ? 373.057 367.667 474.822 1.00 55.87  ? 252 LEU A CD1 1 
ATOM 3281 C CD2 . LEU C 3 252 ? 370.817 367.002 475.603 1.00 55.87  ? 252 LEU A CD2 1 
ATOM 3282 N N   . CYS C 3 253 ? 373.490 363.288 476.254 1.00 60.54  ? 253 CYS A N   1 
ATOM 3283 C CA  . CYS C 3 253 ? 374.062 363.014 477.560 1.00 60.54  ? 253 CYS A CA  1 
ATOM 3284 C C   . CYS C 3 253 ? 375.260 362.076 477.440 1.00 60.54  ? 253 CYS A C   1 
ATOM 3285 O O   . CYS C 3 253 ? 375.529 361.494 476.391 1.00 60.54  ? 253 CYS A O   1 
ATOM 3286 C CB  . CYS C 3 253 ? 373.013 362.410 478.483 1.00 60.54  ? 253 CYS A CB  1 
ATOM 3287 S SG  . CYS C 3 253 ? 371.439 363.254 478.449 1.00 60.54  ? 253 CYS A SG  1 
ATOM 3288 N N   . GLN C 3 254 ? 375.982 361.930 478.542 1.00 63.87  ? 254 GLN A N   1 
ATOM 3289 C CA  . GLN C 3 254 ? 377.163 361.088 478.569 1.00 63.87  ? 254 GLN A CA  1 
ATOM 3290 C C   . GLN C 3 254 ? 376.784 359.637 478.823 1.00 63.87  ? 254 GLN A C   1 
ATOM 3291 O O   . GLN C 3 254 ? 375.628 359.302 479.083 1.00 63.87  ? 254 GLN A O   1 
ATOM 3292 C CB  . GLN C 3 254 ? 378.127 361.557 479.645 1.00 63.87  ? 254 GLN A CB  1 
ATOM 3293 C CG  . GLN C 3 254 ? 378.268 363.048 479.725 1.00 63.87  ? 254 GLN A CG  1 
ATOM 3294 C CD  . GLN C 3 254 ? 379.360 363.459 480.677 1.00 63.87  ? 254 GLN A CD  1 
ATOM 3295 O OE1 . GLN C 3 254 ? 379.735 364.628 480.742 1.00 63.87  ? 254 GLN A OE1 1 
ATOM 3296 N NE2 . GLN C 3 254 ? 379.880 362.496 481.430 1.00 63.87  ? 254 GLN A NE2 1 
ATOM 3297 N N   . TYR C 3 255 ? 377.787 358.771 478.764 1.00 60.35  ? 255 TYR A N   1 
ATOM 3298 C CA  . TYR C 3 255 ? 377.602 357.333 478.885 1.00 60.35  ? 255 TYR A CA  1 
ATOM 3299 C C   . TYR C 3 255 ? 378.056 356.879 480.262 1.00 60.35  ? 255 TYR A C   1 
ATOM 3300 O O   . TYR C 3 255 ? 379.175 357.185 480.680 1.00 60.35  ? 255 TYR A O   1 
ATOM 3301 C CB  . TYR C 3 255 ? 378.394 356.610 477.806 1.00 60.35  ? 255 TYR A CB  1 
ATOM 3302 C CG  . TYR C 3 255 ? 377.740 356.619 476.459 1.00 60.35  ? 255 TYR A CG  1 
ATOM 3303 C CD1 . TYR C 3 255 ? 376.549 355.966 476.254 1.00 60.35  ? 255 TYR A CD1 1 
ATOM 3304 C CD2 . TYR C 3 255 ? 378.321 357.273 475.393 1.00 60.35  ? 255 TYR A CD2 1 
ATOM 3305 C CE1 . TYR C 3 255 ? 375.956 355.958 475.030 1.00 60.35  ? 255 TYR A CE1 1 
ATOM 3306 C CE2 . TYR C 3 255 ? 377.727 357.276 474.165 1.00 60.35  ? 255 TYR A CE2 1 
ATOM 3307 C CZ  . TYR C 3 255 ? 376.546 356.614 473.991 1.00 60.35  ? 255 TYR A CZ  1 
ATOM 3308 O OH  . TYR C 3 255 ? 375.930 356.611 472.770 1.00 60.35  ? 255 TYR A OH  1 
ATOM 3309 N N   . GLU C 3 256 ? 377.193 356.152 480.964 1.00 70.41  ? 256 GLU A N   1 
ATOM 3310 C CA  . GLU C 3 256 ? 377.487 355.681 482.312 1.00 70.41  ? 256 GLU A CA  1 
ATOM 3311 C C   . GLU C 3 256 ? 377.890 354.214 482.348 1.00 70.41  ? 256 GLU A C   1 
ATOM 3312 O O   . GLU C 3 256 ? 379.000 353.881 482.768 1.00 70.41  ? 256 GLU A O   1 
ATOM 3313 C CB  . GLU C 3 256 ? 376.265 355.893 483.206 1.00 70.41  ? 256 GLU A CB  1 
ATOM 3314 C CG  . GLU C 3 256 ? 375.637 357.258 483.062 1.00 70.41  ? 256 GLU A CG  1 
ATOM 3315 C CD  . GLU C 3 256 ? 376.096 358.221 484.128 1.00 70.41  ? 256 GLU A CD  1 
ATOM 3316 O OE1 . GLU C 3 256 ? 376.554 357.746 485.183 1.00 70.41  ? 256 GLU A OE1 1 
ATOM 3317 O OE2 . GLU C 3 256 ? 376.005 359.447 483.914 1.00 70.41  ? 256 GLU A OE2 1 
ATOM 3318 N N   . LYS C 3 257 ? 377.007 353.331 481.903 1.00 72.31  ? 257 LYS A N   1 
ATOM 3319 C CA  . LYS C 3 257 ? 377.235 351.898 481.933 1.00 72.31  ? 257 LYS A CA  1 
ATOM 3320 C C   . LYS C 3 257 ? 377.126 351.351 480.522 1.00 72.31  ? 257 LYS A C   1 
ATOM 3321 O O   . LYS C 3 257 ? 376.468 351.928 479.657 1.00 72.31  ? 257 LYS A O   1 
ATOM 3322 C CB  . LYS C 3 257 ? 376.231 351.193 482.852 1.00 72.31  ? 257 LYS A CB  1 
ATOM 3323 C CG  . LYS C 3 257 ? 376.151 351.771 484.252 1.00 72.31  ? 257 LYS A CG  1 
ATOM 3324 C CD  . LYS C 3 257 ? 377.078 351.049 485.198 1.00 72.31  ? 257 LYS A CD  1 
ATOM 3325 C CE  . LYS C 3 257 ? 376.937 351.587 486.601 1.00 72.31  ? 257 LYS A CE  1 
ATOM 3326 N NZ  . LYS C 3 257 ? 377.363 350.571 487.596 1.00 72.31  ? 257 LYS A NZ  1 
ATOM 3327 N N   . GLN C 3 258 ? 377.781 350.220 480.295 1.00 73.60  ? 258 GLN A N   1 
ATOM 3328 C CA  . GLN C 3 258 ? 377.843 349.652 478.959 1.00 73.60  ? 258 GLN A CA  1 
ATOM 3329 C C   . GLN C 3 258 ? 376.540 348.988 478.559 1.00 73.60  ? 258 GLN A C   1 
ATOM 3330 O O   . GLN C 3 258 ? 376.165 349.013 477.385 1.00 73.60  ? 258 GLN A O   1 
ATOM 3331 C CB  . GLN C 3 258 ? 378.979 348.635 478.877 1.00 73.60  ? 258 GLN A CB  1 
ATOM 3332 C CG  . GLN C 3 258 ? 380.278 349.214 478.393 1.00 73.60  ? 258 GLN A CG  1 
ATOM 3333 C CD  . GLN C 3 258 ? 380.975 350.040 479.446 1.00 73.60  ? 258 GLN A CD  1 
ATOM 3334 O OE1 . GLN C 3 258 ? 381.614 349.504 480.349 1.00 73.60  ? 258 GLN A OE1 1 
ATOM 3335 N NE2 . GLN C 3 258 ? 380.852 351.356 479.342 1.00 73.60  ? 258 GLN A NE2 1 
ATOM 3336 N N   . LYS C 3 259 ? 375.837 348.411 479.524 1.00 72.79  ? 259 LYS A N   1 
ATOM 3337 C CA  . LYS C 3 259 ? 374.726 347.525 479.217 1.00 72.79  ? 259 LYS A CA  1 
ATOM 3338 C C   . LYS C 3 259 ? 373.500 348.289 478.746 1.00 72.79  ? 259 LYS A C   1 
ATOM 3339 O O   . LYS C 3 259 ? 372.741 347.794 477.907 1.00 72.79  ? 259 LYS A O   1 
ATOM 3340 C CB  . LYS C 3 259 ? 374.372 346.711 480.456 1.00 72.79  ? 259 LYS A CB  1 
ATOM 3341 C CG  . LYS C 3 259 ? 375.515 345.905 481.003 1.00 72.79  ? 259 LYS A CG  1 
ATOM 3342 C CD  . LYS C 3 259 ? 375.080 345.164 482.245 1.00 72.79  ? 259 LYS A CD  1 
ATOM 3343 C CE  . LYS C 3 259 ? 374.850 346.132 483.380 1.00 72.79  ? 259 LYS A CE  1 
ATOM 3344 N NZ  . LYS C 3 259 ? 376.118 346.796 483.761 1.00 72.79  ? 259 LYS A NZ  1 
ATOM 3345 N N   . ASN C 3 260 ? 373.289 349.484 479.272 1.00 66.11  ? 260 ASN A N   1 
ATOM 3346 C CA  . ASN C 3 260 ? 371.992 350.124 479.192 1.00 66.11  ? 260 ASN A CA  1 
ATOM 3347 C C   . ASN C 3 260 ? 372.113 351.569 478.726 1.00 66.11  ? 260 ASN A C   1 
ATOM 3348 O O   . ASN C 3 260 ? 373.171 352.028 478.309 1.00 66.11  ? 260 ASN A O   1 
ATOM 3349 C CB  . ASN C 3 260 ? 371.296 349.992 480.540 1.00 66.11  ? 260 ASN A CB  1 
ATOM 3350 C CG  . ASN C 3 260 ? 372.166 350.421 481.676 1.00 66.11  ? 260 ASN A CG  1 
ATOM 3351 O OD1 . ASN C 3 260 ? 373.243 350.958 481.477 1.00 66.11  ? 260 ASN A OD1 1 
ATOM 3352 N ND2 . ASN C 3 260 ? 371.722 350.153 482.885 1.00 66.11  ? 260 ASN A ND2 1 
ATOM 3353 N N   . VAL C 3 261 ? 371.002 352.282 478.812 1.00 61.96  ? 261 VAL A N   1 
ATOM 3354 C CA  . VAL C 3 261 ? 370.853 353.593 478.206 1.00 61.96  ? 261 VAL A CA  1 
ATOM 3355 C C   . VAL C 3 261 ? 370.678 354.588 479.349 1.00 61.96  ? 261 VAL A C   1 
ATOM 3356 O O   . VAL C 3 261 ? 370.296 355.745 479.146 1.00 61.96  ? 261 VAL A O   1 
ATOM 3357 C CB  . VAL C 3 261 ? 369.665 353.560 477.224 1.00 61.96  ? 261 VAL A CB  1 
ATOM 3358 C CG1 . VAL C 3 261 ? 368.373 353.381 477.964 1.00 61.96  ? 261 VAL A CG1 1 
ATOM 3359 C CG2 . VAL C 3 261 ? 369.639 354.726 476.233 1.00 61.96  ? 261 VAL A CG2 1 
ATOM 3360 N N   . ASN C 3 262 ? 370.986 354.144 480.564 1.00 63.25  ? 262 ASN A N   1 
ATOM 3361 C CA  . ASN C 3 262 ? 370.777 354.959 481.749 1.00 63.25  ? 262 ASN A CA  1 
ATOM 3362 C C   . ASN C 3 262 ? 371.705 356.162 481.759 1.00 63.25  ? 262 ASN A C   1 
ATOM 3363 O O   . ASN C 3 262 ? 372.820 356.117 481.239 1.00 63.25  ? 262 ASN A O   1 
ATOM 3364 C CB  . ASN C 3 262 ? 370.998 354.140 483.008 1.00 63.25  ? 262 ASN A CB  1 
ATOM 3365 C CG  . ASN C 3 262 ? 369.821 353.293 483.346 1.00 63.25  ? 262 ASN A CG  1 
ATOM 3366 O OD1 . ASN C 3 262 ? 368.724 353.523 482.859 1.00 63.25  ? 262 ASN A OD1 1 
ATOM 3367 N ND2 . ASN C 3 262 ? 370.027 352.318 484.205 1.00 63.25  ? 262 ASN A ND2 1 
ATOM 3368 N N   . PHE C 3 263 ? 371.226 357.245 482.357 1.00 60.59  ? 263 PHE A N   1 
ATOM 3369 C CA  . PHE C 3 263 ? 371.856 358.548 482.211 1.00 60.59  ? 263 PHE A CA  1 
ATOM 3370 C C   . PHE C 3 263 ? 371.396 359.437 483.349 1.00 60.59  ? 263 PHE A C   1 
ATOM 3371 O O   . PHE C 3 263 ? 370.532 359.066 484.142 1.00 60.59  ? 263 PHE A O   1 
ATOM 3372 C CB  . PHE C 3 263 ? 371.515 359.184 480.862 1.00 60.59  ? 263 PHE A CB  1 
ATOM 3373 C CG  . PHE C 3 263 ? 370.091 359.652 480.743 1.00 60.59  ? 263 PHE A CG  1 
ATOM 3374 C CD1 . PHE C 3 263 ? 369.071 358.759 480.513 1.00 60.59  ? 263 PHE A CD1 1 
ATOM 3375 C CD2 . PHE C 3 263 ? 369.780 360.991 480.830 1.00 60.59  ? 263 PHE A CD2 1 
ATOM 3376 C CE1 . PHE C 3 263 ? 367.776 359.188 480.403 1.00 60.59  ? 263 PHE A CE1 1 
ATOM 3377 C CE2 . PHE C 3 263 ? 368.480 361.419 480.722 1.00 60.59  ? 263 PHE A CE2 1 
ATOM 3378 C CZ  . PHE C 3 263 ? 367.484 360.519 480.505 1.00 60.59  ? 263 PHE A CZ  1 
ATOM 3379 N N   . SER C 3 264 ? 371.993 360.618 483.419 1.00 60.87  ? 264 SER A N   1 
ATOM 3380 C CA  . SER C 3 264 ? 371.554 361.658 484.317 1.00 60.87  ? 264 SER A CA  1 
ATOM 3381 C C   . SER C 3 264 ? 371.371 362.937 483.518 1.00 60.87  ? 264 SER A C   1 
ATOM 3382 O O   . SER C 3 264 ? 372.156 363.199 482.605 1.00 60.87  ? 264 SER A O   1 
ATOM 3383 C CB  . SER C 3 264 ? 372.560 361.884 485.444 1.00 60.87  ? 264 SER A CB  1 
ATOM 3384 O OG  . SER C 3 264 ? 373.776 362.384 484.938 1.00 60.87  ? 264 SER A OG  1 
ATOM 3385 N N   . PRO C 3 265 ? 370.351 363.739 483.817 1.00 59.96  ? 265 PRO A N   1 
ATOM 3386 C CA  . PRO C 3 265 ? 369.932 364.772 482.869 1.00 59.96  ? 265 PRO A CA  1 
ATOM 3387 C C   . PRO C 3 265 ? 370.871 365.960 482.841 1.00 59.96  ? 265 PRO A C   1 
ATOM 3388 O O   . PRO C 3 265 ? 371.507 366.307 483.836 1.00 59.96  ? 265 PRO A O   1 
ATOM 3389 C CB  . PRO C 3 265 ? 368.546 365.173 483.379 1.00 59.96  ? 265 PRO A CB  1 
ATOM 3390 C CG  . PRO C 3 265 ? 368.146 364.089 484.289 1.00 59.96  ? 265 PRO A CG  1 
ATOM 3391 C CD  . PRO C 3 265 ? 369.401 363.640 484.927 1.00 59.96  ? 265 PRO A CD  1 
ATOM 3392 N N   . ILE C 3 266 ? 370.948 366.585 481.673 1.00 59.71  ? 266 ILE A N   1 
ATOM 3393 C CA  . ILE C 3 266 ? 371.842 367.700 481.423 1.00 59.71  ? 266 ILE A CA  1 
ATOM 3394 C C   . ILE C 3 266 ? 371.074 368.714 480.586 1.00 59.71  ? 266 ILE A C   1 
ATOM 3395 O O   . ILE C 3 266 ? 370.027 368.409 480.014 1.00 59.71  ? 266 ILE A O   1 
ATOM 3396 C CB  . ILE C 3 266 ? 373.134 367.224 480.718 1.00 59.71  ? 266 ILE A CB  1 
ATOM 3397 C CG1 . ILE C 3 266 ? 374.313 368.142 481.033 1.00 59.71  ? 266 ILE A CG1 1 
ATOM 3398 C CG2 . ILE C 3 266 ? 372.928 367.065 479.228 1.00 59.71  ? 266 ILE A CG2 1 
ATOM 3399 C CD1 . ILE C 3 266 ? 375.624 367.618 480.534 1.00 59.71  ? 266 ILE A CD1 1 
ATOM 3400 N N   . GLY C 3 267 ? 371.583 369.941 480.547 1.00 59.12  ? 267 GLY A N   1 
ATOM 3401 C CA  . GLY C 3 267 ? 370.955 370.972 479.752 1.00 59.12  ? 267 GLY A CA  1 
ATOM 3402 C C   . GLY C 3 267 ? 371.046 370.693 478.267 1.00 59.12  ? 267 GLY A C   1 
ATOM 3403 O O   . GLY C 3 267 ? 371.818 369.861 477.807 1.00 59.12  ? 267 GLY A O   1 
ATOM 3404 N N   . VAL C 3 268 ? 370.232 371.416 477.505 1.00 58.86  ? 268 VAL A N   1 
ATOM 3405 C CA  . VAL C 3 268 ? 370.088 371.128 476.084 1.00 58.86  ? 268 VAL A CA  1 
ATOM 3406 C C   . VAL C 3 268 ? 371.330 371.563 475.316 1.00 58.86  ? 268 VAL A C   1 
ATOM 3407 O O   . VAL C 3 268 ? 371.855 370.821 474.480 1.00 58.86  ? 268 VAL A O   1 
ATOM 3408 C CB  . VAL C 3 268 ? 368.813 371.792 475.544 1.00 58.86  ? 268 VAL A CB  1 
ATOM 3409 C CG1 . VAL C 3 268 ? 368.799 371.795 474.044 1.00 58.86  ? 268 VAL A CG1 1 
ATOM 3410 C CG2 . VAL C 3 268 ? 367.616 371.054 476.049 1.00 58.86  ? 268 VAL A CG2 1 
ATOM 3411 N N   . THR C 3 269 ? 371.833 372.755 475.602 1.00 65.21  ? 269 THR A N   1 
ATOM 3412 C CA  . THR C 3 269 ? 372.984 373.284 474.893 1.00 65.21  ? 269 THR A CA  1 
ATOM 3413 C C   . THR C 3 269 ? 373.733 374.231 475.814 1.00 65.21  ? 269 THR A C   1 
ATOM 3414 O O   . THR C 3 269 ? 373.237 374.610 476.874 1.00 65.21  ? 269 THR A O   1 
ATOM 3415 C CB  . THR C 3 269 ? 372.552 373.995 473.608 1.00 65.21  ? 269 THR A CB  1 
ATOM 3416 O OG1 . THR C 3 269 ? 373.692 374.276 472.791 1.00 65.21  ? 269 THR A OG1 1 
ATOM 3417 C CG2 . THR C 3 269 ? 371.857 375.280 473.936 1.00 65.21  ? 269 THR A CG2 1 
ATOM 3418 N N   . THR C 3 270 ? 374.948 374.588 475.420 1.00 67.10  ? 270 THR A N   1 
ATOM 3419 C CA  . THR C 3 270 ? 375.690 375.578 476.178 1.00 67.10  ? 270 THR A CA  1 
ATOM 3420 C C   . THR C 3 270 ? 375.049 376.940 475.997 1.00 67.10  ? 270 THR A C   1 
ATOM 3421 O O   . THR C 3 270 ? 374.466 377.240 474.957 1.00 67.10  ? 270 THR A O   1 
ATOM 3422 C CB  . THR C 3 270 ? 377.144 375.627 475.738 1.00 67.10  ? 270 THR A CB  1 
ATOM 3423 O OG1 . THR C 3 270 ? 377.238 376.346 474.506 1.00 67.10  ? 270 THR A OG1 1 
ATOM 3424 C CG2 . THR C 3 270 ? 377.672 374.230 475.540 1.00 67.10  ? 270 THR A CG2 1 
ATOM 3425 N N   . SER C 3 271 ? 375.158 377.766 477.022 1.00 63.75  ? 271 SER A N   1 
ATOM 3426 C CA  . SER C 3 271 ? 374.333 378.952 477.133 1.00 63.75  ? 271 SER A CA  1 
ATOM 3427 C C   . SER C 3 271 ? 375.100 380.220 476.795 1.00 63.75  ? 271 SER A C   1 
ATOM 3428 O O   . SER C 3 271 ? 376.323 380.223 476.669 1.00 63.75  ? 271 SER A O   1 
ATOM 3429 C CB  . SER C 3 271 ? 373.776 379.046 478.537 1.00 63.75  ? 271 SER A CB  1 
ATOM 3430 O OG  . SER C 3 271 ? 374.818 378.906 479.475 1.00 63.75  ? 271 SER A OG  1 
ATOM 3431 N N   . ARG C 3 272 ? 374.350 381.306 476.631 1.00 60.98  ? 272 ARG A N   1 
ATOM 3432 C CA  . ARG C 3 272 ? 374.901 382.634 476.431 1.00 60.98  ? 272 ARG A CA  1 
ATOM 3433 C C   . ARG C 3 272 ? 374.177 383.603 477.348 1.00 60.98  ? 272 ARG A C   1 
ATOM 3434 O O   . ARG C 3 272 ? 373.206 383.249 478.014 1.00 60.98  ? 272 ARG A O   1 
ATOM 3435 C CB  . ARG C 3 272 ? 374.784 383.092 474.976 1.00 60.98  ? 272 ARG A CB  1 
ATOM 3436 C CG  . ARG C 3 272 ? 373.382 383.070 474.432 1.00 60.98  ? 272 ARG A CG  1 
ATOM 3437 C CD  . ARG C 3 272 ? 373.339 383.568 473.010 1.00 60.98  ? 272 ARG A CD  1 
ATOM 3438 N NE  . ARG C 3 272 ? 372.060 383.269 472.388 1.00 60.98  ? 272 ARG A NE  1 
ATOM 3439 C CZ  . ARG C 3 272 ? 371.610 383.857 471.289 1.00 60.98  ? 272 ARG A CZ  1 
ATOM 3440 N NH1 . ARG C 3 272 ? 372.334 384.781 470.685 1.00 60.98  ? 272 ARG A NH1 1 
ATOM 3441 N NH2 . ARG C 3 272 ? 370.433 383.523 470.795 1.00 60.98  ? 272 ARG A NH2 1 
ATOM 3442 N N   . THR C 3 273 ? 374.650 384.846 477.365 1.00 64.42  ? 273 THR A N   1 
ATOM 3443 C CA  . THR C 3 273 ? 374.208 385.788 478.382 1.00 64.42  ? 273 THR A CA  1 
ATOM 3444 C C   . THR C 3 273 ? 372.842 386.384 478.079 1.00 64.42  ? 273 THR A C   1 
ATOM 3445 O O   . THR C 3 273 ? 371.970 386.397 478.952 1.00 64.42  ? 273 THR A O   1 
ATOM 3446 C CB  . THR C 3 273 ? 375.233 386.900 478.528 1.00 64.42  ? 273 THR A CB  1 
ATOM 3447 O OG1 . THR C 3 273 ? 376.507 386.320 478.816 1.00 64.42  ? 273 THR A OG1 1 
ATOM 3448 C CG2 . THR C 3 273 ? 374.852 387.817 479.664 1.00 64.42  ? 273 THR A CG2 1 
ATOM 3449 N N   . ASP C 3 274 ? 372.629 386.866 476.862 1.00 66.35  ? 274 ASP A N   1 
ATOM 3450 C CA  . ASP C 3 274 ? 371.369 387.490 476.499 1.00 66.35  ? 274 ASP A CA  1 
ATOM 3451 C C   . ASP C 3 274 ? 370.956 386.944 475.142 1.00 66.35  ? 274 ASP A C   1 
ATOM 3452 O O   . ASP C 3 274 ? 371.794 386.513 474.349 1.00 66.35  ? 274 ASP A O   1 
ATOM 3453 C CB  . ASP C 3 274 ? 371.508 389.016 476.498 1.00 66.35  ? 274 ASP A CB  1 
ATOM 3454 C CG  . ASP C 3 274 ? 370.192 389.733 476.255 1.00 66.35  ? 274 ASP A CG  1 
ATOM 3455 O OD1 . ASP C 3 274 ? 369.123 389.107 476.417 1.00 66.35  ? 274 ASP A OD1 1 
ATOM 3456 O OD2 . ASP C 3 274 ? 370.228 390.930 475.905 1.00 66.35  ? 274 ASP A OD2 1 
ATOM 3457 N N   . ILE C 3 275 ? 369.652 386.949 474.886 1.00 62.43  ? 275 ILE A N   1 
ATOM 3458 C CA  . ILE C 3 275 ? 369.133 386.435 473.629 1.00 62.43  ? 275 ILE A CA  1 
ATOM 3459 C C   . ILE C 3 275 ? 369.504 387.326 472.442 1.00 62.43  ? 275 ILE A C   1 
ATOM 3460 O O   . ILE C 3 275 ? 369.844 386.815 471.371 1.00 62.43  ? 275 ILE A O   1 
ATOM 3461 C CB  . ILE C 3 275 ? 367.612 386.233 473.754 1.00 62.43  ? 275 ILE A CB  1 
ATOM 3462 C CG1 . ILE C 3 275 ? 366.986 385.822 472.428 1.00 62.43  ? 275 ILE A CG1 1 
ATOM 3463 C CG2 . ILE C 3 275 ? 366.941 387.445 474.342 1.00 62.43  ? 275 ILE A CG2 1 
ATOM 3464 C CD1 . ILE C 3 275 ? 365.560 385.419 472.544 1.00 62.43  ? 275 ILE A CD1 1 
ATOM 3465 N N   . ILE C 3 276 ? 369.523 388.640 472.613 1.00 63.83  ? 276 ILE A N   1 
ATOM 3466 C CA  . ILE C 3 276 ? 369.898 389.518 471.519 1.00 63.83  ? 276 ILE A CA  1 
ATOM 3467 C C   . ILE C 3 276 ? 371.409 389.653 471.473 1.00 63.83  ? 276 ILE A C   1 
ATOM 3468 O O   . ILE C 3 276 ? 371.962 390.213 470.527 1.00 63.83  ? 276 ILE A O   1 
ATOM 3469 C CB  . ILE C 3 276 ? 369.239 390.886 471.645 1.00 63.83  ? 276 ILE A CB  1 
ATOM 3470 C CG1 . ILE C 3 276 ? 369.954 391.714 472.702 1.00 63.83  ? 276 ILE A CG1 1 
ATOM 3471 C CG2 . ILE C 3 276 ? 367.787 390.740 472.017 1.00 63.83  ? 276 ILE A CG2 1 
ATOM 3472 C CD1 . ILE C 3 276 ? 369.607 393.174 472.655 1.00 63.83  ? 276 ILE A CD1 1 
ATOM 3473 N N   . ARG D 4 14  ? 335.032 362.351 456.035 1.00 94.76  ? 14  ARG B N   1 
ATOM 3474 C CA  . ARG D 4 14  ? 333.947 362.658 456.955 1.00 94.76  ? 14  ARG B CA  1 
ATOM 3475 C C   . ARG D 4 14  ? 333.167 361.415 457.331 1.00 94.76  ? 14  ARG B C   1 
ATOM 3476 O O   . ARG D 4 14  ? 332.629 360.735 456.455 1.00 94.76  ? 14  ARG B O   1 
ATOM 3477 C CB  . ARG D 4 14  ? 332.992 363.678 456.347 1.00 94.76  ? 14  ARG B CB  1 
ATOM 3478 C CG  . ARG D 4 14  ? 333.653 364.875 455.722 1.00 94.76  ? 14  ARG B CG  1 
ATOM 3479 C CD  . ARG D 4 14  ? 332.730 366.059 455.826 1.00 94.76  ? 14  ARG B CD  1 
ATOM 3480 N NE  . ARG D 4 14  ? 332.388 366.307 457.216 1.00 94.76  ? 14  ARG B NE  1 
ATOM 3481 C CZ  . ARG D 4 14  ? 332.985 367.217 457.972 1.00 94.76  ? 14  ARG B CZ  1 
ATOM 3482 N NH1 . ARG D 4 14  ? 333.942 367.975 457.462 1.00 94.76  ? 14  ARG B NH1 1 
ATOM 3483 N NH2 . ARG D 4 14  ? 332.617 367.376 459.231 1.00 94.76  ? 14  ARG B NH2 1 
ATOM 3484 N N   . SER D 4 15  ? 333.106 361.154 458.639 1.00 93.26  ? 15  SER B N   1 
ATOM 3485 C CA  . SER D 4 15  ? 332.339 360.060 459.240 1.00 93.26  ? 15  SER B CA  1 
ATOM 3486 C C   . SER D 4 15  ? 332.759 358.700 458.680 1.00 93.26  ? 15  SER B C   1 
ATOM 3487 O O   . SER D 4 15  ? 331.991 358.003 458.020 1.00 93.26  ? 15  SER B O   1 
ATOM 3488 C CB  . SER D 4 15  ? 330.833 360.288 459.089 1.00 93.26  ? 15  SER B CB  1 
ATOM 3489 O OG  . SER D 4 15  ? 330.355 361.158 460.100 1.00 93.26  ? 15  SER B OG  1 
ATOM 3490 N N   . ILE D 4 16  ? 334.005 358.346 458.948 1.00 90.29  ? 16  ILE B N   1 
ATOM 3491 C CA  . ILE D 4 16  ? 334.529 357.041 458.572 1.00 90.29  ? 16  ILE B CA  1 
ATOM 3492 C C   . ILE D 4 16  ? 334.150 356.027 459.648 1.00 90.29  ? 16  ILE B C   1 
ATOM 3493 O O   . ILE D 4 16  ? 333.916 356.382 460.808 1.00 90.29  ? 16  ILE B O   1 
ATOM 3494 C CB  . ILE D 4 16  ? 336.053 357.139 458.344 1.00 90.29  ? 16  ILE B CB  1 
ATOM 3495 C CG1 . ILE D 4 16  ? 336.574 355.965 457.514 1.00 90.29  ? 16  ILE B CG1 1 
ATOM 3496 C CG2 . ILE D 4 16  ? 336.809 357.289 459.652 1.00 90.29  ? 16  ILE B CG2 1 
ATOM 3497 C CD1 . ILE D 4 16  ? 337.823 356.290 456.729 1.00 90.29  ? 16  ILE B CD1 1 
ATOM 3498 N N   . THR D 4 17  ? 334.027 354.758 459.263 1.00 90.76  ? 17  THR B N   1 
ATOM 3499 C CA  . THR D 4 17  ? 333.535 353.735 460.173 1.00 90.76  ? 17  THR B CA  1 
ATOM 3500 C C   . THR D 4 17  ? 334.285 352.424 459.991 1.00 90.76  ? 17  THR B C   1 
ATOM 3501 O O   . THR D 4 17  ? 334.740 352.088 458.895 1.00 90.76  ? 17  THR B O   1 
ATOM 3502 C CB  . THR D 4 17  ? 332.031 353.498 459.991 1.00 90.76  ? 17  THR B CB  1 
ATOM 3503 O OG1 . THR D 4 17  ? 331.622 352.381 460.789 1.00 90.76  ? 17  THR B OG1 1 
ATOM 3504 C CG2 . THR D 4 17  ? 331.686 353.245 458.538 1.00 90.76  ? 17  THR B CG2 1 
ATOM 3505 N N   . LEU D 4 18  ? 334.410 351.688 461.093 1.00 86.28  ? 18  LEU B N   1 
ATOM 3506 C CA  . LEU D 4 18  ? 335.096 350.401 461.117 1.00 86.28  ? 18  LEU B CA  1 
ATOM 3507 C C   . LEU D 4 18  ? 334.376 349.495 462.096 1.00 86.28  ? 18  LEU B C   1 
ATOM 3508 O O   . LEU D 4 18  ? 334.405 349.750 463.301 1.00 86.28  ? 18  LEU B O   1 
ATOM 3509 C CB  . LEU D 4 18  ? 336.553 350.551 461.531 1.00 86.28  ? 18  LEU B CB  1 
ATOM 3510 C CG  . LEU D 4 18  ? 337.583 351.000 460.512 1.00 86.28  ? 18  LEU B CG  1 
ATOM 3511 C CD1 . LEU D 4 18  ? 338.896 351.186 461.209 1.00 86.28  ? 18  LEU B CD1 1 
ATOM 3512 C CD2 . LEU D 4 18  ? 337.708 349.947 459.449 1.00 86.28  ? 18  LEU B CD2 1 
ATOM 3513 N N   . GLY D 4 19  ? 333.761 348.438 461.586 1.00 88.91  ? 19  GLY B N   1 
ATOM 3514 C CA  . GLY D 4 19  ? 333.040 347.511 462.429 1.00 88.91  ? 19  GLY B CA  1 
ATOM 3515 C C   . GLY D 4 19  ? 331.791 348.125 463.010 1.00 88.91  ? 19  GLY B C   1 
ATOM 3516 O O   . GLY D 4 19  ? 330.840 348.428 462.287 1.00 88.91  ? 19  GLY B O   1 
ATOM 3517 N N   . ASN D 4 20  ? 331.792 348.330 464.319 1.00 89.32  ? 20  ASN B N   1 
ATOM 3518 C CA  . ASN D 4 20  ? 330.654 348.900 465.019 1.00 89.32  ? 20  ASN B CA  1 
ATOM 3519 C C   . ASN D 4 20  ? 331.039 350.187 465.731 1.00 89.32  ? 20  ASN B C   1 
ATOM 3520 O O   . ASN D 4 20  ? 330.702 350.380 466.896 1.00 89.32  ? 20  ASN B O   1 
ATOM 3521 C CB  . ASN D 4 20  ? 330.078 347.895 466.007 1.00 89.32  ? 20  ASN B CB  1 
ATOM 3522 C CG  . ASN D 4 20  ? 331.134 347.289 466.880 1.00 89.32  ? 20  ASN B CG  1 
ATOM 3523 O OD1 . ASN D 4 20  ? 331.792 346.329 466.499 1.00 89.32  ? 20  ASN B OD1 1 
ATOM 3524 N ND2 . ASN D 4 20  ? 331.314 347.853 468.060 1.00 89.32  ? 20  ASN B ND2 1 
ATOM 3525 N N   . SER D 4 21  ? 331.759 351.066 465.048 1.00 89.06  ? 21  SER B N   1 
ATOM 3526 C CA  . SER D 4 21  ? 332.151 352.354 465.590 1.00 89.06  ? 21  SER B CA  1 
ATOM 3527 C C   . SER D 4 21  ? 332.216 353.365 464.457 1.00 89.06  ? 21  SER B C   1 
ATOM 3528 O O   . SER D 4 21  ? 332.383 352.996 463.293 1.00 89.06  ? 21  SER B O   1 
ATOM 3529 C CB  . SER D 4 21  ? 333.496 352.270 466.288 1.00 89.06  ? 21  SER B CB  1 
ATOM 3530 O OG  . SER D 4 21  ? 334.445 351.652 465.448 1.00 89.06  ? 21  SER B OG  1 
ATOM 3531 N N   . THR D 4 22  ? 332.081 354.644 464.797 1.00 91.73  ? 22  THR B N   1 
ATOM 3532 C CA  . THR D 4 22  ? 332.112 355.691 463.784 1.00 91.73  ? 22  THR B CA  1 
ATOM 3533 C C   . THR D 4 22  ? 332.671 356.969 464.385 1.00 91.73  ? 22  THR B C   1 
ATOM 3534 O O   . THR D 4 22  ? 332.109 357.490 465.350 1.00 91.73  ? 22  THR B O   1 
ATOM 3535 C CB  . THR D 4 22  ? 330.713 355.954 463.214 1.00 91.73  ? 22  THR B CB  1 
ATOM 3536 O OG1 . THR D 4 22  ? 330.243 354.793 462.523 1.00 91.73  ? 22  THR B OG1 1 
ATOM 3537 C CG2 . THR D 4 22  ? 330.736 357.118 462.248 1.00 91.73  ? 22  THR B CG2 1 
ATOM 3538 N N   . ILE D 4 23  ? 333.772 357.468 463.826 1.00 86.45  ? 23  ILE B N   1 
ATOM 3539 C CA  . ILE D 4 23  ? 334.288 358.784 464.167 1.00 86.45  ? 23  ILE B CA  1 
ATOM 3540 C C   . ILE D 4 23  ? 334.253 359.639 462.909 1.00 86.45  ? 23  ILE B C   1 
ATOM 3541 O O   . ILE D 4 23  ? 334.134 359.131 461.798 1.00 86.45  ? 23  ILE B O   1 
ATOM 3542 C CB  . ILE D 4 23  ? 335.712 358.739 464.750 1.00 86.45  ? 23  ILE B CB  1 
ATOM 3543 C CG1 . ILE D 4 23  ? 336.727 358.397 463.666 1.00 86.45  ? 23  ILE B CG1 1 
ATOM 3544 C CG2 . ILE D 4 23  ? 335.797 357.711 465.858 1.00 86.45  ? 23  ILE B CG2 1 
ATOM 3545 C CD1 . ILE D 4 23  ? 338.136 358.670 464.076 1.00 86.45  ? 23  ILE B CD1 1 
ATOM 3546 N N   . THR D 4 24  ? 334.367 360.951 463.092 1.00 91.57  ? 24  THR B N   1 
ATOM 3547 C CA  . THR D 4 24  ? 334.315 361.903 461.990 1.00 91.57  ? 24  THR B CA  1 
ATOM 3548 C C   . THR D 4 24  ? 335.582 362.750 461.947 1.00 91.57  ? 24  THR B C   1 
ATOM 3549 O O   . THR D 4 24  ? 336.193 363.024 462.985 1.00 91.57  ? 24  THR B O   1 
ATOM 3550 C CB  . THR D 4 24  ? 333.070 362.789 462.090 1.00 91.57  ? 24  THR B CB  1 
ATOM 3551 O OG1 . THR D 4 24  ? 333.046 363.707 460.991 1.00 91.57  ? 24  THR B OG1 1 
ATOM 3552 C CG2 . THR D 4 24  ? 333.015 363.549 463.409 1.00 91.57  ? 24  THR B CG2 1 
ATOM 3553 N N   . THR D 4 25  ? 335.992 363.128 460.741 1.00 94.25  ? 25  THR B N   1 
ATOM 3554 C CA  . THR D 4 25  ? 337.202 363.893 460.466 1.00 94.25  ? 25  THR B CA  1 
ATOM 3555 C C   . THR D 4 25  ? 336.876 364.881 459.335 1.00 94.25  ? 25  THR B C   1 
ATOM 3556 O O   . THR D 4 25  ? 335.856 364.746 458.660 1.00 94.25  ? 25  THR B O   1 
ATOM 3557 C CB  . THR D 4 25  ? 338.349 362.938 460.106 1.00 94.25  ? 25  THR B CB  1 
ATOM 3558 O OG1 . THR D 4 25  ? 338.288 361.777 460.938 1.00 94.25  ? 25  THR B OG1 1 
ATOM 3559 C CG2 . THR D 4 25  ? 339.709 363.575 460.331 1.00 94.25  ? 25  THR B CG2 1 
ATOM 3560 N N   . GLN D 4 26  ? 337.727 365.887 459.136 1.00 95.09  ? 26  GLN B N   1 
ATOM 3561 C CA  . GLN D 4 26  ? 337.558 366.813 458.014 1.00 95.09  ? 26  GLN B CA  1 
ATOM 3562 C C   . GLN D 4 26  ? 337.771 366.114 456.676 1.00 95.09  ? 26  GLN B C   1 
ATOM 3563 O O   . GLN D 4 26  ? 337.524 366.691 455.618 1.00 95.09  ? 26  GLN B O   1 
ATOM 3564 C CB  . GLN D 4 26  ? 338.513 368.011 458.134 1.00 95.09  ? 26  GLN B CB  1 
ATOM 3565 C CG  . GLN D 4 26  ? 340.005 367.686 457.952 1.00 95.09  ? 26  GLN B CG  1 
ATOM 3566 C CD  . GLN D 4 26  ? 340.542 367.959 456.544 1.00 95.09  ? 26  GLN B CD  1 
ATOM 3567 O OE1 . GLN D 4 26  ? 339.837 368.476 455.680 1.00 95.09  ? 26  GLN B OE1 1 
ATOM 3568 N NE2 . GLN D 4 26  ? 341.804 367.609 456.320 1.00 95.09  ? 26  GLN B NE2 1 
ATOM 3569 N N   . ASN D 4 30  ? 344.808 366.109 455.992 1.00 72.92  ? 30  ASN B N   1 
ATOM 3570 C CA  . ASN D 4 30  ? 346.258 366.184 456.115 1.00 72.92  ? 30  ASN B CA  1 
ATOM 3571 C C   . ASN D 4 30  ? 346.805 365.036 456.944 1.00 72.92  ? 30  ASN B C   1 
ATOM 3572 O O   . ASN D 4 30  ? 346.761 365.069 458.169 1.00 72.92  ? 30  ASN B O   1 
ATOM 3573 C CB  . ASN D 4 30  ? 346.674 367.510 456.740 1.00 72.92  ? 30  ASN B CB  1 
ATOM 3574 C CG  . ASN D 4 30  ? 348.155 367.761 456.625 1.00 72.92  ? 30  ASN B CG  1 
ATOM 3575 O OD1 . ASN D 4 30  ? 348.806 367.281 455.703 1.00 72.92  ? 30  ASN B OD1 1 
ATOM 3576 N ND2 . ASN D 4 30  ? 348.698 368.524 457.559 1.00 72.92  ? 30  ASN B ND2 1 
ATOM 3577 N N   . VAL D 4 31  ? 347.340 364.030 456.262 1.00 69.46  ? 31  VAL B N   1 
ATOM 3578 C CA  . VAL D 4 31  ? 347.838 362.817 456.892 1.00 69.46  ? 31  VAL B CA  1 
ATOM 3579 C C   . VAL D 4 31  ? 349.327 362.701 456.589 1.00 69.46  ? 31  VAL B C   1 
ATOM 3580 O O   . VAL D 4 31  ? 349.793 363.178 455.549 1.00 69.46  ? 31  VAL B O   1 
ATOM 3581 C CB  . VAL D 4 31  ? 347.041 361.581 456.417 1.00 69.46  ? 31  VAL B CB  1 
ATOM 3582 C CG1 . VAL D 4 31  ? 347.327 361.234 454.965 1.00 69.46  ? 31  VAL B CG1 1 
ATOM 3583 C CG2 . VAL D 4 31  ? 347.288 360.391 457.296 1.00 69.46  ? 31  VAL B CG2 1 
ATOM 3584 N N   . VAL D 4 32  ? 350.085 362.163 457.539 1.00 65.85  ? 32  VAL B N   1 
ATOM 3585 C CA  . VAL D 4 32  ? 351.485 361.814 457.335 1.00 65.85  ? 32  VAL B CA  1 
ATOM 3586 C C   . VAL D 4 32  ? 351.649 360.321 457.574 1.00 65.85  ? 32  VAL B C   1 
ATOM 3587 O O   . VAL D 4 32  ? 351.309 359.805 458.643 1.00 65.85  ? 32  VAL B O   1 
ATOM 3588 C CB  . VAL D 4 32  ? 352.424 362.667 458.209 1.00 65.85  ? 32  VAL B CB  1 
ATOM 3589 C CG1 . VAL D 4 32  ? 351.916 362.798 459.597 1.00 65.85  ? 32  VAL B CG1 1 
ATOM 3590 C CG2 . VAL D 4 32  ? 353.798 362.047 458.266 1.00 65.85  ? 32  VAL B CG2 1 
ATOM 3591 N N   . VAL D 4 33  ? 352.146 359.626 456.562 1.00 68.50  ? 33  VAL B N   1 
ATOM 3592 C CA  . VAL D 4 33  ? 352.221 358.175 456.569 1.00 68.50  ? 33  VAL B CA  1 
ATOM 3593 C C   . VAL D 4 33  ? 353.677 357.756 456.744 1.00 68.50  ? 33  VAL B C   1 
ATOM 3594 O O   . VAL D 4 33  ? 354.531 358.046 455.899 1.00 68.50  ? 33  VAL B O   1 
ATOM 3595 C CB  . VAL D 4 33  ? 351.569 357.573 455.315 1.00 68.50  ? 33  VAL B CB  1 
ATOM 3596 C CG1 . VAL D 4 33  ? 351.978 358.299 454.050 1.00 68.50  ? 33  VAL B CG1 1 
ATOM 3597 C CG2 . VAL D 4 33  ? 351.917 356.116 455.202 1.00 68.50  ? 33  VAL B CG2 1 
ATOM 3598 N N   . GLY D 4 34  ? 353.954 357.162 457.908 1.00 67.25  ? 34  GLY B N   1 
ATOM 3599 C CA  . GLY D 4 34  ? 355.124 356.366 458.243 1.00 67.25  ? 34  GLY B CA  1 
ATOM 3600 C C   . GLY D 4 34  ? 356.474 356.763 457.713 1.00 67.25  ? 34  GLY B C   1 
ATOM 3601 O O   . GLY D 4 34  ? 356.852 357.934 457.750 1.00 67.25  ? 34  GLY B O   1 
ATOM 3602 N N   . TYR D 4 35  ? 357.198 355.783 457.189 1.00 65.05  ? 35  TYR B N   1 
ATOM 3603 C CA  . TYR D 4 35  ? 358.424 356.025 456.451 1.00 65.05  ? 35  TYR B CA  1 
ATOM 3604 C C   . TYR D 4 35  ? 358.193 355.983 454.952 1.00 65.05  ? 35  TYR B C   1 
ATOM 3605 O O   . TYR D 4 35  ? 359.035 355.486 454.205 1.00 65.05  ? 35  TYR B O   1 
ATOM 3606 C CB  . TYR D 4 35  ? 359.489 355.023 456.867 1.00 65.05  ? 35  TYR B CB  1 
ATOM 3607 C CG  . TYR D 4 35  ? 360.060 355.356 458.208 1.00 65.05  ? 35  TYR B CG  1 
ATOM 3608 C CD1 . TYR D 4 35  ? 361.055 356.300 458.329 1.00 65.05  ? 35  TYR B CD1 1 
ATOM 3609 C CD2 . TYR D 4 35  ? 359.589 354.748 459.355 1.00 65.05  ? 35  TYR B CD2 1 
ATOM 3610 C CE1 . TYR D 4 35  ? 361.575 356.617 459.544 1.00 65.05  ? 35  TYR B CE1 1 
ATOM 3611 C CE2 . TYR D 4 35  ? 360.104 355.063 460.574 1.00 65.05  ? 35  TYR B CE2 1 
ATOM 3612 C CZ  . TYR D 4 35  ? 361.095 355.999 460.659 1.00 65.05  ? 35  TYR B CZ  1 
ATOM 3613 O OH  . TYR D 4 35  ? 361.627 356.332 461.870 1.00 65.05  ? 35  TYR B OH  1 
ATOM 3614 N N   . GLY D 4 36  ? 357.051 356.484 454.504 1.00 73.09  ? 36  GLY B N   1 
ATOM 3615 C CA  . GLY D 4 36  ? 356.698 356.498 453.107 1.00 73.09  ? 36  GLY B CA  1 
ATOM 3616 C C   . GLY D 4 36  ? 355.890 355.307 452.654 1.00 73.09  ? 36  GLY B C   1 
ATOM 3617 O O   . GLY D 4 36  ? 355.229 355.393 451.616 1.00 73.09  ? 36  GLY B O   1 
ATOM 3618 N N   . VAL D 4 37  ? 355.905 354.212 453.406 1.00 78.33  ? 37  VAL B N   1 
ATOM 3619 C CA  . VAL D 4 37  ? 355.254 352.975 453.000 1.00 78.33  ? 37  VAL B CA  1 
ATOM 3620 C C   . VAL D 4 37  ? 353.949 352.816 453.761 1.00 78.33  ? 37  VAL B C   1 
ATOM 3621 O O   . VAL D 4 37  ? 353.767 353.358 454.856 1.00 78.33  ? 37  VAL B O   1 
ATOM 3622 C CB  . VAL D 4 37  ? 356.164 351.753 453.225 1.00 78.33  ? 37  VAL B CB  1 
ATOM 3623 C CG1 . VAL D 4 37  ? 357.377 351.834 452.329 1.00 78.33  ? 37  VAL B CG1 1 
ATOM 3624 C CG2 . VAL D 4 37  ? 356.585 351.675 454.670 1.00 78.33  ? 37  VAL B CG2 1 
ATOM 3625 N N   . TRP D 4 38  ? 353.038 352.056 453.171 1.00 87.14  ? 38  TRP B N   1 
ATOM 3626 C CA  . TRP D 4 38  ? 351.698 351.779 453.652 1.00 87.14  ? 38  TRP B CA  1 
ATOM 3627 C C   . TRP D 4 38  ? 351.638 350.379 454.250 1.00 87.14  ? 38  TRP B C   1 
ATOM 3628 O O   . TRP D 4 38  ? 352.279 349.463 453.732 1.00 87.14  ? 38  TRP B O   1 
ATOM 3629 C CB  . TRP D 4 38  ? 350.696 351.893 452.504 1.00 87.14  ? 38  TRP B CB  1 
ATOM 3630 C CG  . TRP D 4 38  ? 349.308 352.113 452.961 1.00 87.14  ? 38  TRP B CG  1 
ATOM 3631 C CD1 . TRP D 4 38  ? 348.374 351.162 453.227 1.00 87.14  ? 38  TRP B CD1 1 
ATOM 3632 C CD2 . TRP D 4 38  ? 348.681 353.373 453.205 1.00 87.14  ? 38  TRP B CD2 1 
ATOM 3633 N NE1 . TRP D 4 38  ? 347.205 351.749 453.635 1.00 87.14  ? 38  TRP B NE1 1 
ATOM 3634 C CE2 . TRP D 4 38  ? 347.369 353.109 453.626 1.00 87.14  ? 38  TRP B CE2 1 
ATOM 3635 C CE3 . TRP D 4 38  ? 349.102 354.700 453.108 1.00 87.14  ? 38  TRP B CE3 1 
ATOM 3636 C CZ2 . TRP D 4 38  ? 346.477 354.121 453.952 1.00 87.14  ? 38  TRP B CZ2 1 
ATOM 3637 C CZ3 . TRP D 4 38  ? 348.213 355.700 453.431 1.00 87.14  ? 38  TRP B CZ3 1 
ATOM 3638 C CH2 . TRP D 4 38  ? 346.918 355.407 453.847 1.00 87.14  ? 38  TRP B CH2 1 
ATOM 3639 N N   . PRO D 4 39  ? 350.906 350.173 455.346 1.00 90.87  ? 39  PRO B N   1 
ATOM 3640 C CA  . PRO D 4 39  ? 350.872 348.844 455.979 1.00 90.87  ? 39  PRO B CA  1 
ATOM 3641 C C   . PRO D 4 39  ? 350.074 347.835 455.164 1.00 90.87  ? 39  PRO B C   1 
ATOM 3642 O O   . PRO D 4 39  ? 349.031 348.162 454.596 1.00 90.87  ? 39  PRO B O   1 
ATOM 3643 C CB  . PRO D 4 39  ? 350.206 349.114 457.333 1.00 90.87  ? 39  PRO B CB  1 
ATOM 3644 C CG  . PRO D 4 39  ? 350.339 350.570 457.552 1.00 90.87  ? 39  PRO B CG  1 
ATOM 3645 C CD  . PRO D 4 39  ? 350.302 351.202 456.204 1.00 90.87  ? 39  PRO B CD  1 
ATOM 3646 N N   . GLU D 4 40  ? 350.569 346.596 455.123 1.00 103.65 ? 40  GLU B N   1 
ATOM 3647 C CA  . GLU D 4 40  ? 349.925 345.509 454.396 1.00 103.65 ? 40  GLU B CA  1 
ATOM 3648 C C   . GLU D 4 40  ? 350.301 344.177 455.038 1.00 103.65 ? 40  GLU B C   1 
ATOM 3649 O O   . GLU D 4 40  ? 351.183 344.105 455.897 1.00 103.65 ? 40  GLU B O   1 
ATOM 3650 C CB  . GLU D 4 40  ? 350.308 345.531 452.907 1.00 103.65 ? 40  GLU B CB  1 
ATOM 3651 C CG  . GLU D 4 40  ? 351.626 344.844 452.544 1.00 103.65 ? 40  GLU B CG  1 
ATOM 3652 C CD  . GLU D 4 40  ? 352.854 345.433 453.215 1.00 103.65 ? 40  GLU B CD  1 
ATOM 3653 O OE1 . GLU D 4 40  ? 352.850 346.631 453.561 1.00 103.65 ? 40  GLU B OE1 1 
ATOM 3654 O OE2 . GLU D 4 40  ? 353.833 344.684 453.405 1.00 103.65 ? 40  GLU B OE2 1 
ATOM 3655 N N   . TYR D 4 41  ? 349.631 343.112 454.603 1.00 111.29 ? 41  TYR B N   1 
ATOM 3656 C CA  . TYR D 4 41  ? 349.814 341.781 455.174 1.00 111.29 ? 41  TYR B CA  1 
ATOM 3657 C C   . TYR D 4 41  ? 351.126 341.167 454.672 1.00 111.29 ? 41  TYR B C   1 
ATOM 3658 O O   . TYR D 4 41  ? 351.838 341.738 453.843 1.00 111.29 ? 41  TYR B O   1 
ATOM 3659 C CB  . TYR D 4 41  ? 348.617 340.894 454.840 1.00 111.29 ? 41  TYR B CB  1 
ATOM 3660 C CG  . TYR D 4 41  ? 347.279 341.425 455.314 1.00 111.29 ? 41  TYR B CG  1 
ATOM 3661 C CD1 . TYR D 4 41  ? 346.792 341.115 456.579 1.00 111.29 ? 41  TYR B CD1 1 
ATOM 3662 C CD2 . TYR D 4 41  ? 346.491 342.217 454.486 1.00 111.29 ? 41  TYR B CD2 1 
ATOM 3663 C CE1 . TYR D 4 41  ? 345.569 341.595 457.014 1.00 111.29 ? 41  TYR B CE1 1 
ATOM 3664 C CE2 . TYR D 4 41  ? 345.266 342.702 454.913 1.00 111.29 ? 41  TYR B CE2 1 
ATOM 3665 C CZ  . TYR D 4 41  ? 344.811 342.387 456.175 1.00 111.29 ? 41  TYR B CZ  1 
ATOM 3666 O OH  . TYR D 4 41  ? 343.594 342.870 456.590 1.00 111.29 ? 41  TYR B OH  1 
ATOM 3667 N N   . LEU D 4 42  ? 351.457 339.981 455.177 1.00 107.15 ? 42  LEU B N   1 
ATOM 3668 C CA  . LEU D 4 42  ? 352.656 339.254 454.749 1.00 107.15 ? 42  LEU B CA  1 
ATOM 3669 C C   . LEU D 4 42  ? 352.605 338.775 453.300 1.00 107.15 ? 42  LEU B C   1 
ATOM 3670 O O   . LEU D 4 42  ? 353.520 338.094 452.826 1.00 107.15 ? 42  LEU B O   1 
ATOM 3671 C CB  . LEU D 4 42  ? 352.896 338.051 455.656 1.00 107.15 ? 42  LEU B CB  1 
ATOM 3672 C CG  . LEU D 4 42  ? 353.539 338.297 457.009 1.00 107.15 ? 42  LEU B CG  1 
ATOM 3673 C CD1 . LEU D 4 42  ? 353.458 337.054 457.876 1.00 107.15 ? 42  LEU B CD1 1 
ATOM 3674 C CD2 . LEU D 4 42  ? 354.980 338.658 456.743 1.00 107.15 ? 42  LEU B CD2 1 
ATOM 3675 N N   . ASP D 4 51  ? 355.252 328.445 460.922 1.00 133.48 ? 51  ASP B N   1 
ATOM 3676 C CA  . ASP D 4 51  ? 354.166 327.749 460.241 1.00 133.48 ? 51  ASP B CA  1 
ATOM 3677 C C   . ASP D 4 51  ? 353.336 328.711 459.401 1.00 133.48 ? 51  ASP B C   1 
ATOM 3678 O O   . ASP D 4 51  ? 353.887 329.488 458.623 1.00 133.48 ? 51  ASP B O   1 
ATOM 3679 C CB  . ASP D 4 51  ? 353.291 327.003 461.254 1.00 133.48 ? 51  ASP B CB  1 
ATOM 3680 C CG  . ASP D 4 51  ? 352.955 327.840 462.470 1.00 133.48 ? 51  ASP B CG  1 
ATOM 3681 O OD1 . ASP D 4 51  ? 353.693 328.809 462.746 1.00 133.48 ? 51  ASP B OD1 1 
ATOM 3682 O OD2 . ASP D 4 51  ? 351.961 327.521 463.155 1.00 133.48 ? 51  ASP B OD2 1 
ATOM 3683 N N   . GLN D 4 52  ? 352.012 328.657 459.544 1.00 133.76 ? 52  GLN B N   1 
ATOM 3684 C CA  . GLN D 4 52  ? 351.141 329.499 458.746 1.00 133.76 ? 52  GLN B CA  1 
ATOM 3685 C C   . GLN D 4 52  ? 350.396 330.497 459.622 1.00 133.76 ? 52  GLN B C   1 
ATOM 3686 O O   . GLN D 4 52  ? 349.622 330.096 460.499 1.00 133.76 ? 52  GLN B O   1 
ATOM 3687 C CB  . GLN D 4 52  ? 350.124 328.654 457.956 1.00 133.76 ? 52  GLN B CB  1 
ATOM 3688 C CG  . GLN D 4 52  ? 349.142 329.431 457.062 1.00 133.76 ? 52  GLN B CG  1 
ATOM 3689 C CD  . GLN D 4 52  ? 349.750 330.598 456.291 1.00 133.76 ? 52  GLN B CD  1 
ATOM 3690 O OE1 . GLN D 4 52  ? 350.817 330.483 455.684 1.00 133.76 ? 52  GLN B OE1 1 
ATOM 3691 N NE2 . GLN D 4 52  ? 349.056 331.729 456.305 1.00 133.76 ? 52  GLN B NE2 1 
ATOM 3692 N N   . PRO D 4 53  ? 350.609 331.804 459.412 1.00 129.56 ? 53  PRO B N   1 
ATOM 3693 C CA  . PRO D 4 53  ? 349.810 332.802 460.130 1.00 129.56 ? 53  PRO B CA  1 
ATOM 3694 C C   . PRO D 4 53  ? 348.438 333.000 459.514 1.00 129.56 ? 53  PRO B C   1 
ATOM 3695 O O   . PRO D 4 53  ? 348.298 333.158 458.297 1.00 129.56 ? 53  PRO B O   1 
ATOM 3696 C CB  . PRO D 4 53  ? 350.660 334.072 460.027 1.00 129.56 ? 53  PRO B CB  1 
ATOM 3697 C CG  . PRO D 4 53  ? 351.456 333.893 458.801 1.00 129.56 ? 53  PRO B CG  1 
ATOM 3698 C CD  . PRO D 4 53  ? 351.719 332.419 458.664 1.00 129.56 ? 53  PRO B CD  1 
ATOM 3699 N N   . THR D 4 54  ? 347.421 333.007 460.365 1.00 126.63 ? 54  THR B N   1 
ATOM 3700 C CA  . THR D 4 54  ? 346.034 333.128 459.958 1.00 126.63 ? 54  THR B CA  1 
ATOM 3701 C C   . THR D 4 54  ? 345.678 334.610 459.983 1.00 126.63 ? 54  THR B C   1 
ATOM 3702 O O   . THR D 4 54  ? 346.333 335.399 460.667 1.00 126.63 ? 54  THR B O   1 
ATOM 3703 C CB  . THR D 4 54  ? 345.139 332.309 460.901 1.00 126.63 ? 54  THR B CB  1 
ATOM 3704 O OG1 . THR D 4 54  ? 345.747 331.032 461.115 1.00 126.63 ? 54  THR B OG1 1 
ATOM 3705 C CG2 . THR D 4 54  ? 343.766 332.043 460.291 1.00 126.63 ? 54  THR B CG2 1 
ATOM 3706 N N   . GLN D 4 55  ? 344.674 334.993 459.197 1.00 124.71 ? 55  GLN B N   1 
ATOM 3707 C CA  . GLN D 4 55  ? 344.270 336.390 459.035 1.00 124.71 ? 55  GLN B CA  1 
ATOM 3708 C C   . GLN D 4 55  ? 342.929 336.666 459.701 1.00 124.71 ? 55  GLN B C   1 
ATOM 3709 O O   . GLN D 4 55  ? 341.872 336.395 459.103 1.00 124.71 ? 55  GLN B O   1 
ATOM 3710 C CB  . GLN D 4 55  ? 344.192 336.738 457.551 1.00 124.71 ? 55  GLN B CB  1 
ATOM 3711 C CG  . GLN D 4 55  ? 344.250 338.214 457.247 1.00 124.71 ? 55  GLN B CG  1 
ATOM 3712 C CD  . GLN D 4 55  ? 344.006 338.505 455.780 1.00 124.71 ? 55  GLN B CD  1 
ATOM 3713 O OE1 . GLN D 4 55  ? 344.867 339.053 455.091 1.00 124.71 ? 55  GLN B OE1 1 
ATOM 3714 N NE2 . GLN D 4 55  ? 342.824 338.140 455.294 1.00 124.71 ? 55  GLN B NE2 1 
ATOM 3715 N N   . PRO D 4 56  ? 342.905 337.175 460.935 1.00 124.93 ? 56  PRO B N   1 
ATOM 3716 C CA  . PRO D 4 56  ? 341.677 337.795 461.447 1.00 124.93 ? 56  PRO B CA  1 
ATOM 3717 C C   . PRO D 4 56  ? 341.664 339.290 461.168 1.00 124.93 ? 56  PRO B C   1 
ATOM 3718 O O   . PRO D 4 56  ? 342.569 340.038 461.547 1.00 124.93 ? 56  PRO B O   1 
ATOM 3719 C CB  . PRO D 4 56  ? 341.740 337.495 462.950 1.00 124.93 ? 56  PRO B CB  1 
ATOM 3720 C CG  . PRO D 4 56  ? 343.195 337.327 463.245 1.00 124.93 ? 56  PRO B CG  1 
ATOM 3721 C CD  . PRO D 4 56  ? 343.946 337.084 461.970 1.00 124.93 ? 56  PRO B CD  1 
ATOM 3722 N N   . ASP D 4 57  ? 340.605 339.730 460.493 1.00 126.25 ? 57  ASP B N   1 
ATOM 3723 C CA  . ASP D 4 57  ? 340.578 341.061 459.900 1.00 126.25 ? 57  ASP B CA  1 
ATOM 3724 C C   . ASP D 4 57  ? 339.305 341.850 460.153 1.00 126.25 ? 57  ASP B C   1 
ATOM 3725 O O   . ASP D 4 57  ? 339.337 343.078 460.028 1.00 126.25 ? 57  ASP B O   1 
ATOM 3726 C CB  . ASP D 4 57  ? 340.802 340.961 458.383 1.00 126.25 ? 57  ASP B CB  1 
ATOM 3727 C CG  . ASP D 4 57  ? 340.106 339.758 457.770 1.00 126.25 ? 57  ASP B CG  1 
ATOM 3728 O OD1 . ASP D 4 57  ? 339.340 339.084 458.488 1.00 126.25 ? 57  ASP B OD1 1 
ATOM 3729 O OD2 . ASP D 4 57  ? 340.330 339.483 456.574 1.00 126.25 ? 57  ASP B OD2 1 
ATOM 3730 N N   . VAL D 4 58  ? 338.187 341.202 460.481 1.00 120.96 ? 58  VAL B N   1 
ATOM 3731 C CA  . VAL D 4 58  ? 336.935 341.935 460.620 1.00 120.96 ? 58  VAL B CA  1 
ATOM 3732 C C   . VAL D 4 58  ? 336.523 342.054 462.085 1.00 120.96 ? 58  VAL B C   1 
ATOM 3733 O O   . VAL D 4 58  ? 335.844 343.020 462.463 1.00 120.96 ? 58  VAL B O   1 
ATOM 3734 C CB  . VAL D 4 58  ? 335.862 341.244 459.755 1.00 120.96 ? 58  VAL B CB  1 
ATOM 3735 C CG1 . VAL D 4 58  ? 334.549 342.031 459.716 1.00 120.96 ? 58  VAL B CG1 1 
ATOM 3736 C CG2 . VAL D 4 58  ? 336.383 341.009 458.348 1.00 120.96 ? 58  VAL B CG2 1 
ATOM 3737 N N   . ALA D 4 59  ? 336.985 341.145 462.941 1.00 111.52 ? 59  ALA B N   1 
ATOM 3738 C CA  . ALA D 4 59  ? 336.474 341.041 464.297 1.00 111.52 ? 59  ALA B CA  1 
ATOM 3739 C C   . ALA D 4 59  ? 337.014 342.095 465.255 1.00 111.52 ? 59  ALA B C   1 
ATOM 3740 O O   . ALA D 4 59  ? 336.285 342.508 466.163 1.00 111.52 ? 59  ALA B O   1 
ATOM 3741 C CB  . ALA D 4 59  ? 336.771 339.646 464.855 1.00 111.52 ? 59  ALA B CB  1 
ATOM 3742 N N   . THR D 4 60  ? 338.254 342.556 465.081 1.00 101.01 ? 60  THR B N   1 
ATOM 3743 C CA  . THR D 4 60  ? 338.846 343.530 465.988 1.00 101.01 ? 60  THR B CA  1 
ATOM 3744 C C   . THR D 4 60  ? 339.282 344.815 465.310 1.00 101.01 ? 60  THR B C   1 
ATOM 3745 O O   . THR D 4 60  ? 339.748 345.723 466.001 1.00 101.01 ? 60  THR B O   1 
ATOM 3746 C CB  . THR D 4 60  ? 340.068 342.943 466.706 1.00 101.01 ? 60  THR B CB  1 
ATOM 3747 O OG1 . THR D 4 60  ? 341.036 342.523 465.738 1.00 101.01 ? 60  THR B OG1 1 
ATOM 3748 C CG2 . THR D 4 60  ? 339.679 341.770 467.566 1.00 101.01 ? 60  THR B CG2 1 
ATOM 3749 N N   . CYS D 4 61  ? 339.167 344.908 463.987 1.00 96.49  ? 61  CYS B N   1 
ATOM 3750 C CA  . CYS D 4 61  ? 339.531 346.121 463.261 1.00 96.49  ? 61  CYS B CA  1 
ATOM 3751 C C   . CYS D 4 61  ? 338.440 347.161 463.491 1.00 96.49  ? 61  CYS B C   1 
ATOM 3752 O O   . CYS D 4 61  ? 337.405 347.182 462.824 1.00 96.49  ? 61  CYS B O   1 
ATOM 3753 C CB  . CYS D 4 61  ? 339.720 345.817 461.783 1.00 96.49  ? 61  CYS B CB  1 
ATOM 3754 S SG  . CYS D 4 61  ? 340.783 346.959 460.879 1.00 96.49  ? 61  CYS B SG  1 
ATOM 3755 N N   . ARG D 4 62  ? 338.683 348.033 464.467 1.00 83.28  ? 62  ARG B N   1 
ATOM 3756 C CA  . ARG D 4 62  ? 337.783 349.133 464.778 1.00 83.28  ? 62  ARG B CA  1 
ATOM 3757 C C   . ARG D 4 62  ? 338.580 350.217 465.485 1.00 83.28  ? 62  ARG B C   1 
ATOM 3758 O O   . ARG D 4 62  ? 339.780 350.078 465.710 1.00 83.28  ? 62  ARG B O   1 
ATOM 3759 C CB  . ARG D 4 62  ? 336.601 348.669 465.627 1.00 83.28  ? 62  ARG B CB  1 
ATOM 3760 C CG  . ARG D 4 62  ? 337.002 347.859 466.812 1.00 83.28  ? 62  ARG B CG  1 
ATOM 3761 C CD  . ARG D 4 62  ? 335.820 347.199 467.458 1.00 83.28  ? 62  ARG B CD  1 
ATOM 3762 N NE  . ARG D 4 62  ? 334.912 348.147 468.087 1.00 83.28  ? 62  ARG B NE  1 
ATOM 3763 C CZ  . ARG D 4 62  ? 335.082 348.660 469.298 1.00 83.28  ? 62  ARG B CZ  1 
ATOM 3764 N NH1 . ARG D 4 62  ? 336.138 348.339 470.017 1.00 83.28  ? 62  ARG B NH1 1 
ATOM 3765 N NH2 . ARG D 4 62  ? 334.193 349.501 469.792 1.00 83.28  ? 62  ARG B NH2 1 
ATOM 3766 N N   . PHE D 4 63  ? 337.902 351.306 465.835 1.00 77.23  ? 63  PHE B N   1 
ATOM 3767 C CA  . PHE D 4 63  ? 338.549 352.459 466.449 1.00 77.23  ? 63  PHE B CA  1 
ATOM 3768 C C   . PHE D 4 63  ? 338.500 352.321 467.962 1.00 77.23  ? 63  PHE B C   1 
ATOM 3769 O O   . PHE D 4 63  ? 337.420 352.274 468.551 1.00 77.23  ? 63  PHE B O   1 
ATOM 3770 C CB  . PHE D 4 63  ? 337.874 353.752 466.017 1.00 77.23  ? 63  PHE B CB  1 
ATOM 3771 C CG  . PHE D 4 63  ? 338.129 354.122 464.601 1.00 77.23  ? 63  PHE B CG  1 
ATOM 3772 C CD1 . PHE D 4 63  ? 339.352 354.611 464.213 1.00 77.23  ? 63  PHE B CD1 1 
ATOM 3773 C CD2 . PHE D 4 63  ? 337.133 354.000 463.660 1.00 77.23  ? 63  PHE B CD2 1 
ATOM 3774 C CE1 . PHE D 4 63  ? 339.584 354.956 462.907 1.00 77.23  ? 63  PHE B CE1 1 
ATOM 3775 C CE2 . PHE D 4 63  ? 337.356 354.347 462.356 1.00 77.23  ? 63  PHE B CE2 1 
ATOM 3776 C CZ  . PHE D 4 63  ? 338.581 354.827 461.978 1.00 77.23  ? 63  PHE B CZ  1 
ATOM 3777 N N   . TYR D 4 64  ? 339.664 352.280 468.595 1.00 74.66  ? 64  TYR B N   1 
ATOM 3778 C CA  . TYR D 4 64  ? 339.754 352.143 470.043 1.00 74.66  ? 64  TYR B CA  1 
ATOM 3779 C C   . TYR D 4 64  ? 340.091 353.500 470.637 1.00 74.66  ? 64  TYR B C   1 
ATOM 3780 O O   . TYR D 4 64  ? 341.257 353.873 470.731 1.00 74.66  ? 64  TYR B O   1 
ATOM 3781 C CB  . TYR D 4 64  ? 340.798 351.103 470.420 1.00 74.66  ? 64  TYR B CB  1 
ATOM 3782 C CG  . TYR D 4 64  ? 340.369 349.690 470.143 1.00 74.66  ? 64  TYR B CG  1 
ATOM 3783 C CD1 . TYR D 4 64  ? 340.523 349.136 468.889 1.00 74.66  ? 64  TYR B CD1 1 
ATOM 3784 C CD2 . TYR D 4 64  ? 339.804 348.914 471.134 1.00 74.66  ? 64  TYR B CD2 1 
ATOM 3785 C CE1 . TYR D 4 64  ? 340.130 347.856 468.631 1.00 74.66  ? 64  TYR B CE1 1 
ATOM 3786 C CE2 . TYR D 4 64  ? 339.407 347.630 470.884 1.00 74.66  ? 64  TYR B CE2 1 
ATOM 3787 C CZ  . TYR D 4 64  ? 339.573 347.109 469.630 1.00 74.66  ? 64  TYR B CZ  1 
ATOM 3788 O OH  . TYR D 4 64  ? 339.180 345.825 469.367 1.00 74.66  ? 64  TYR B OH  1 
ATOM 3789 N N   . THR D 4 65  ? 339.072 354.237 471.055 1.00 65.54  ? 65  THR B N   1 
ATOM 3790 C CA  . THR D 4 65  ? 339.266 355.563 471.627 1.00 65.54  ? 65  THR B CA  1 
ATOM 3791 C C   . THR D 4 65  ? 339.689 355.422 473.079 1.00 65.54  ? 65  THR B C   1 
ATOM 3792 O O   . THR D 4 65  ? 338.910 354.961 473.915 1.00 65.54  ? 65  THR B O   1 
ATOM 3793 C CB  . THR D 4 65  ? 337.986 356.378 471.520 1.00 65.54  ? 65  THR B CB  1 
ATOM 3794 O OG1 . THR D 4 65  ? 337.687 356.613 470.144 1.00 65.54  ? 65  THR B OG1 1 
ATOM 3795 C CG2 . THR D 4 65  ? 338.149 357.700 472.204 1.00 65.54  ? 65  THR B CG2 1 
ATOM 3796 N N   . LEU D 4 66  ? 340.918 355.811 473.388 1.00 63.40  ? 66  LEU B N   1 
ATOM 3797 C CA  . LEU D 4 66  ? 341.341 355.840 474.776 1.00 63.40  ? 66  LEU B CA  1 
ATOM 3798 C C   . LEU D 4 66  ? 340.762 357.067 475.465 1.00 63.40  ? 66  LEU B C   1 
ATOM 3799 O O   . LEU D 4 66  ? 340.248 357.983 474.823 1.00 63.40  ? 66  LEU B O   1 
ATOM 3800 C CB  . LEU D 4 66  ? 342.859 355.858 474.878 1.00 63.40  ? 66  LEU B CB  1 
ATOM 3801 C CG  . LEU D 4 66  ? 343.600 355.036 473.840 1.00 63.40  ? 66  LEU B CG  1 
ATOM 3802 C CD1 . LEU D 4 66  ? 345.053 355.374 473.908 1.00 63.40  ? 66  LEU B CD1 1 
ATOM 3803 C CD2 . LEU D 4 66  ? 343.390 353.576 474.105 1.00 63.40  ? 66  LEU B CD2 1 
ATOM 3804 N N   . GLU D 4 67  ? 340.852 357.082 476.790 1.00 65.73  ? 67  GLU B N   1 
ATOM 3805 C CA  . GLU D 4 67  ? 340.274 358.187 477.530 1.00 65.73  ? 67  GLU B CA  1 
ATOM 3806 C C   . GLU D 4 67  ? 341.127 359.437 477.377 1.00 65.73  ? 67  GLU B C   1 
ATOM 3807 O O   . GLU D 4 67  ? 342.298 359.383 477.006 1.00 65.73  ? 67  GLU B O   1 
ATOM 3808 C CB  . GLU D 4 67  ? 340.117 357.839 479.002 1.00 65.73  ? 67  GLU B CB  1 
ATOM 3809 C CG  . GLU D 4 67  ? 341.406 357.690 479.740 1.00 65.73  ? 67  GLU B CG  1 
ATOM 3810 C CD  . GLU D 4 67  ? 341.191 357.602 481.232 1.00 65.73  ? 67  GLU B CD  1 
ATOM 3811 O OE1 . GLU D 4 67  ? 340.104 358.002 481.697 1.00 65.73  ? 67  GLU B OE1 1 
ATOM 3812 O OE2 . GLU D 4 67  ? 342.103 357.131 481.942 1.00 65.73  ? 67  GLU B OE2 1 
ATOM 3813 N N   . SER D 4 68  ? 340.514 360.577 477.653 1.00 60.01  ? 68  SER B N   1 
ATOM 3814 C CA  . SER D 4 68  ? 341.138 361.850 477.351 1.00 60.01  ? 68  SER B CA  1 
ATOM 3815 C C   . SER D 4 68  ? 342.073 362.277 478.465 1.00 60.01  ? 68  SER B C   1 
ATOM 3816 O O   . SER D 4 68  ? 341.819 362.024 479.643 1.00 60.01  ? 68  SER B O   1 
ATOM 3817 C CB  . SER D 4 68  ? 340.075 362.917 477.127 1.00 60.01  ? 68  SER B CB  1 
ATOM 3818 O OG  . SER D 4 68  ? 339.237 362.565 476.045 1.00 60.01  ? 68  SER B OG  1 
ATOM 3819 N N   . VAL D 4 69  ? 343.164 362.915 478.080 1.00 54.67  ? 69  VAL B N   1 
ATOM 3820 C CA  . VAL D 4 69  ? 344.056 363.563 479.009 1.00 54.67  ? 69  VAL B CA  1 
ATOM 3821 C C   . VAL D 4 69  ? 343.736 365.047 479.009 1.00 54.67  ? 69  VAL B C   1 
ATOM 3822 O O   . VAL D 4 69  ? 343.139 365.581 478.077 1.00 54.67  ? 69  VAL B O   1 
ATOM 3823 C CB  . VAL D 4 69  ? 345.527 363.303 478.652 1.00 54.67  ? 69  VAL B CB  1 
ATOM 3824 C CG1 . VAL D 4 69  ? 345.768 361.839 478.591 1.00 54.67  ? 69  VAL B CG1 1 
ATOM 3825 C CG2 . VAL D 4 69  ? 345.848 363.900 477.323 1.00 54.67  ? 69  VAL B CG2 1 
ATOM 3826 N N   . GLN D 4 70  ? 344.118 365.725 480.078 1.00 59.29  ? 70  GLN B N   1 
ATOM 3827 C CA  . GLN D 4 70  ? 343.799 367.128 480.259 1.00 59.29  ? 70  GLN B CA  1 
ATOM 3828 C C   . GLN D 4 70  ? 345.067 367.948 480.128 1.00 59.29  ? 70  GLN B C   1 
ATOM 3829 O O   . GLN D 4 70  ? 346.026 367.730 480.870 1.00 59.29  ? 70  GLN B O   1 
ATOM 3830 C CB  . GLN D 4 70  ? 343.172 367.367 481.624 1.00 59.29  ? 70  GLN B CB  1 
ATOM 3831 C CG  . GLN D 4 70  ? 341.915 366.597 481.855 1.00 59.29  ? 70  GLN B CG  1 
ATOM 3832 C CD  . GLN D 4 70  ? 341.268 366.974 483.158 1.00 59.29  ? 70  GLN B CD  1 
ATOM 3833 O OE1 . GLN D 4 70  ? 341.944 367.371 484.105 1.00 59.29  ? 70  GLN B OE1 1 
ATOM 3834 N NE2 . GLN D 4 70  ? 339.951 366.842 483.225 1.00 59.29  ? 70  GLN B NE2 1 
ATOM 3835 N N   . TRP D 4 71  ? 345.067 368.889 479.202 1.00 53.09  ? 71  TRP B N   1 
ATOM 3836 C CA  . TRP D 4 71  ? 346.206 369.763 478.976 1.00 53.09  ? 71  TRP B CA  1 
ATOM 3837 C C   . TRP D 4 71  ? 346.033 370.992 479.856 1.00 53.09  ? 71  TRP B C   1 
ATOM 3838 O O   . TRP D 4 71  ? 345.231 371.873 479.546 1.00 53.09  ? 71  TRP B O   1 
ATOM 3839 C CB  . TRP D 4 71  ? 346.299 370.124 477.498 1.00 53.09  ? 71  TRP B CB  1 
ATOM 3840 C CG  . TRP D 4 71  ? 347.462 370.941 477.089 1.00 53.09  ? 71  TRP B CG  1 
ATOM 3841 C CD1 . TRP D 4 71  ? 348.545 371.276 477.833 1.00 53.09  ? 71  TRP B CD1 1 
ATOM 3842 C CD2 . TRP D 4 71  ? 347.662 371.527 475.812 1.00 53.09  ? 71  TRP B CD2 1 
ATOM 3843 N NE1 . TRP D 4 71  ? 349.398 372.046 477.104 1.00 53.09  ? 71  TRP B NE1 1 
ATOM 3844 C CE2 . TRP D 4 71  ? 348.874 372.212 475.853 1.00 53.09  ? 71  TRP B CE2 1 
ATOM 3845 C CE3 . TRP D 4 71  ? 346.922 371.547 474.638 1.00 53.09  ? 71  TRP B CE3 1 
ATOM 3846 C CZ2 . TRP D 4 71  ? 349.365 372.899 474.771 1.00 53.09  ? 71  TRP B CZ2 1 
ATOM 3847 C CZ3 . TRP D 4 71  ? 347.410 372.229 473.571 1.00 53.09  ? 71  TRP B CZ3 1 
ATOM 3848 C CH2 . TRP D 4 71  ? 348.616 372.896 473.639 1.00 53.09  ? 71  TRP B CH2 1 
ATOM 3849 N N   . MET D 4 72  ? 346.784 371.050 480.947 1.00 59.77  ? 72  MET B N   1 
ATOM 3850 C CA  . MET D 4 72  ? 346.754 372.170 481.867 1.00 59.77  ? 72  MET B CA  1 
ATOM 3851 C C   . MET D 4 72  ? 347.871 373.139 481.521 1.00 59.77  ? 72  MET B C   1 
ATOM 3852 O O   . MET D 4 72  ? 348.518 373.021 480.483 1.00 59.77  ? 72  MET B O   1 
ATOM 3853 C CB  . MET D 4 72  ? 346.867 371.676 483.301 1.00 59.77  ? 72  MET B CB  1 
ATOM 3854 C CG  . MET D 4 72  ? 345.953 370.540 483.602 1.00 59.77  ? 72  MET B CG  1 
ATOM 3855 S SD  . MET D 4 72  ? 346.231 369.879 485.235 1.00 59.77  ? 72  MET B SD  1 
ATOM 3856 C CE  . MET D 4 72  ? 345.651 368.209 484.980 1.00 59.77  ? 72  MET B CE  1 
ATOM 3857 N N   . LYS D 4 73  ? 348.109 374.109 482.398 1.00 58.99  ? 73  LYS B N   1 
ATOM 3858 C CA  . LYS D 4 73  ? 349.096 375.139 482.105 1.00 58.99  ? 73  LYS B CA  1 
ATOM 3859 C C   . LYS D 4 73  ? 350.510 374.604 482.242 1.00 58.99  ? 73  LYS B C   1 
ATOM 3860 O O   . LYS D 4 73  ? 351.285 374.615 481.282 1.00 58.99  ? 73  LYS B O   1 
ATOM 3861 C CB  . LYS D 4 73  ? 348.889 376.340 483.019 1.00 58.99  ? 73  LYS B CB  1 
ATOM 3862 C CG  . LYS D 4 73  ? 348.306 377.526 482.305 1.00 58.99  ? 73  LYS B CG  1 
ATOM 3863 C CD  . LYS D 4 73  ? 348.385 378.775 483.135 1.00 58.99  ? 73  LYS B CD  1 
ATOM 3864 C CE  . LYS D 4 73  ? 347.780 379.932 482.379 1.00 58.99  ? 73  LYS B CE  1 
ATOM 3865 N NZ  . LYS D 4 73  ? 348.048 381.223 483.049 1.00 58.99  ? 73  LYS B NZ  1 
ATOM 3866 N N   . ASN D 4 74  ? 350.872 374.132 483.428 1.00 64.22  ? 74  ASN B N   1 
ATOM 3867 C CA  . ASN D 4 74  ? 352.222 373.621 483.641 1.00 64.22  ? 74  ASN B CA  1 
ATOM 3868 C C   . ASN D 4 74  ? 352.300 372.123 483.401 1.00 64.22  ? 74  ASN B C   1 
ATOM 3869 O O   . ASN D 4 74  ? 352.904 371.389 484.168 1.00 64.22  ? 74  ASN B O   1 
ATOM 3870 C CB  . ASN D 4 74  ? 352.679 373.965 485.048 1.00 64.22  ? 74  ASN B CB  1 
ATOM 3871 C CG  . ASN D 4 74  ? 352.470 375.412 485.378 1.00 64.22  ? 74  ASN B CG  1 
ATOM 3872 O OD1 . ASN D 4 74  ? 353.051 376.291 484.749 1.00 64.22  ? 74  ASN B OD1 1 
ATOM 3873 N ND2 . ASN D 4 74  ? 351.620 375.676 486.358 1.00 64.22  ? 74  ASN B ND2 1 
ATOM 3874 N N   . SER D 4 75  ? 351.730 371.668 482.301 1.00 59.33  ? 75  SER B N   1 
ATOM 3875 C CA  . SER D 4 75  ? 351.810 370.273 481.920 1.00 59.33  ? 75  SER B CA  1 
ATOM 3876 C C   . SER D 4 75  ? 353.116 370.036 481.183 1.00 59.33  ? 75  SER B C   1 
ATOM 3877 O O   . SER D 4 75  ? 353.759 370.970 480.710 1.00 59.33  ? 75  SER B O   1 
ATOM 3878 C CB  . SER D 4 75  ? 350.622 369.894 481.049 1.00 59.33  ? 75  SER B CB  1 
ATOM 3879 O OG  . SER D 4 75  ? 350.669 368.535 480.700 1.00 59.33  ? 75  SER B OG  1 
ATOM 3880 N N   . ALA D 4 76  ? 353.513 368.783 481.094 1.00 55.93  ? 76  ALA B N   1 
ATOM 3881 C CA  . ALA D 4 76  ? 354.834 368.483 480.565 1.00 55.93  ? 76  ALA B CA  1 
ATOM 3882 C C   . ALA D 4 76  ? 354.825 367.540 479.379 1.00 55.93  ? 76  ALA B C   1 
ATOM 3883 O O   . ALA D 4 76  ? 355.655 367.688 478.488 1.00 55.93  ? 76  ALA B O   1 
ATOM 3884 C CB  . ALA D 4 76  ? 355.710 367.900 481.669 1.00 55.93  ? 76  ALA B CB  1 
ATOM 3885 N N   . GLY D 4 77  ? 353.929 366.572 479.344 1.00 54.53  ? 77  GLY B N   1 
ATOM 3886 C CA  . GLY D 4 77  ? 353.881 365.626 478.247 1.00 54.53  ? 77  GLY B CA  1 
ATOM 3887 C C   . GLY D 4 77  ? 353.175 364.357 478.663 1.00 54.53  ? 77  GLY B C   1 
ATOM 3888 O O   . GLY D 4 77  ? 352.745 364.200 479.799 1.00 54.53  ? 77  GLY B O   1 
ATOM 3889 N N   . TRP D 4 78  ? 353.032 363.448 477.695 1.00 53.12  ? 78  TRP B N   1 
ATOM 3890 C CA  . TRP D 4 78  ? 352.397 362.151 477.897 1.00 53.12  ? 78  TRP B CA  1 
ATOM 3891 C C   . TRP D 4 78  ? 353.052 361.125 476.983 1.00 53.12  ? 78  TRP B C   1 
ATOM 3892 O O   . TRP D 4 78  ? 353.683 361.486 475.993 1.00 53.12  ? 78  TRP B O   1 
ATOM 3893 C CB  . TRP D 4 78  ? 350.889 362.199 477.620 1.00 53.12  ? 78  TRP B CB  1 
ATOM 3894 C CG  . TRP D 4 78  ? 350.148 363.159 478.473 1.00 53.12  ? 78  TRP B CG  1 
ATOM 3895 C CD1 . TRP D 4 78  ? 349.628 362.926 479.700 1.00 53.12  ? 78  TRP B CD1 1 
ATOM 3896 C CD2 . TRP D 4 78  ? 349.864 364.523 478.170 1.00 53.12  ? 78  TRP B CD2 1 
ATOM 3897 N NE1 . TRP D 4 78  ? 349.031 364.055 480.183 1.00 53.12  ? 78  TRP B NE1 1 
ATOM 3898 C CE2 . TRP D 4 78  ? 349.166 365.053 479.258 1.00 53.12  ? 78  TRP B CE2 1 
ATOM 3899 C CE3 . TRP D 4 78  ? 350.134 365.347 477.079 1.00 53.12  ? 78  TRP B CE3 1 
ATOM 3900 C CZ2 . TRP D 4 78  ? 348.734 366.360 479.287 1.00 53.12  ? 78  TRP B CZ2 1 
ATOM 3901 C CZ3 . TRP D 4 78  ? 349.705 366.638 477.113 1.00 53.12  ? 78  TRP B CZ3 1 
ATOM 3902 C CH2 . TRP D 4 78  ? 349.015 367.136 478.206 1.00 53.12  ? 78  TRP B CH2 1 
ATOM 3903 N N   . TRP D 4 79  ? 352.910 359.837 477.312 1.00 56.53  ? 79  TRP B N   1 
ATOM 3904 C CA  . TRP D 4 79  ? 353.329 358.805 476.370 1.00 56.53  ? 79  TRP B CA  1 
ATOM 3905 C C   . TRP D 4 79  ? 352.485 357.550 476.534 1.00 56.53  ? 79  TRP B C   1 
ATOM 3906 O O   . TRP D 4 79  ? 351.916 357.313 477.598 1.00 56.53  ? 79  TRP B O   1 
ATOM 3907 C CB  . TRP D 4 79  ? 354.821 358.435 476.489 1.00 56.53  ? 79  TRP B CB  1 
ATOM 3908 C CG  . TRP D 4 79  ? 355.255 357.526 477.607 1.00 56.53  ? 79  TRP B CG  1 
ATOM 3909 C CD1 . TRP D 4 79  ? 355.243 356.170 477.600 1.00 56.53  ? 79  TRP B CD1 1 
ATOM 3910 C CD2 . TRP D 4 79  ? 355.852 357.905 478.844 1.00 56.53  ? 79  TRP B CD2 1 
ATOM 3911 N NE1 . TRP D 4 79  ? 355.745 355.680 478.770 1.00 56.53  ? 79  TRP B NE1 1 
ATOM 3912 C CE2 . TRP D 4 79  ? 356.127 356.730 479.551 1.00 56.53  ? 79  TRP B CE2 1 
ATOM 3913 C CE3 . TRP D 4 79  ? 356.155 359.124 479.434 1.00 56.53  ? 79  TRP B CE3 1 
ATOM 3914 C CZ2 . TRP D 4 79  ? 356.691 356.739 480.811 1.00 56.53  ? 79  TRP B CZ2 1 
ATOM 3915 C CZ3 . TRP D 4 79  ? 356.714 359.127 480.686 1.00 56.53  ? 79  TRP B CZ3 1 
ATOM 3916 C CH2 . TRP D 4 79  ? 356.977 357.949 481.360 1.00 56.53  ? 79  TRP B CH2 1 
ATOM 3917 N N   . TRP D 4 80  ? 352.412 356.757 475.464 1.00 55.45  ? 80  TRP B N   1 
ATOM 3918 C CA  . TRP D 4 80  ? 351.743 355.462 475.429 1.00 55.45  ? 80  TRP B CA  1 
ATOM 3919 C C   . TRP D 4 80  ? 352.611 354.467 474.681 1.00 55.45  ? 80  TRP B C   1 
ATOM 3920 O O   . TRP D 4 80  ? 353.078 354.762 473.584 1.00 55.45  ? 80  TRP B O   1 
ATOM 3921 C CB  . TRP D 4 80  ? 350.404 355.514 474.698 1.00 55.45  ? 80  TRP B CB  1 
ATOM 3922 C CG  . TRP D 4 80  ? 349.339 356.336 475.298 1.00 55.45  ? 80  TRP B CG  1 
ATOM 3923 C CD1 . TRP D 4 80  ? 348.359 355.913 476.128 1.00 55.45  ? 80  TRP B CD1 1 
ATOM 3924 C CD2 . TRP D 4 80  ? 349.104 357.720 475.068 1.00 55.45  ? 80  TRP B CD2 1 
ATOM 3925 N NE1 . TRP D 4 80  ? 347.540 356.955 476.458 1.00 55.45  ? 80  TRP B NE1 1 
ATOM 3926 C CE2 . TRP D 4 80  ? 347.980 358.078 475.815 1.00 55.45  ? 80  TRP B CE2 1 
ATOM 3927 C CE3 . TRP D 4 80  ? 349.747 358.697 474.313 1.00 55.45  ? 80  TRP B CE3 1 
ATOM 3928 C CZ2 . TRP D 4 80  ? 347.486 359.364 475.830 1.00 55.45  ? 80  TRP B CZ2 1 
ATOM 3929 C CZ3 . TRP D 4 80  ? 349.258 359.966 474.330 1.00 55.45  ? 80  TRP B CZ3 1 
ATOM 3930 C CH2 . TRP D 4 80  ? 348.142 360.294 475.082 1.00 55.45  ? 80  TRP B CH2 1 
ATOM 3931 N N   . LYS D 4 81  ? 352.802 353.278 475.245 1.00 59.66  ? 81  LYS B N   1 
ATOM 3932 C CA  . LYS D 4 81  ? 353.462 352.190 474.531 1.00 59.66  ? 81  LYS B CA  1 
ATOM 3933 C C   . LYS D 4 81  ? 352.415 351.445 473.723 1.00 59.66  ? 81  LYS B C   1 
ATOM 3934 O O   . LYS D 4 81  ? 351.374 351.062 474.258 1.00 59.66  ? 81  LYS B O   1 
ATOM 3935 C CB  . LYS D 4 81  ? 354.160 351.242 475.496 1.00 59.66  ? 81  LYS B CB  1 
ATOM 3936 C CG  . LYS D 4 81  ? 355.171 351.907 476.380 1.00 59.66  ? 81  LYS B CG  1 
ATOM 3937 C CD  . LYS D 4 81  ? 356.507 351.999 475.711 1.00 59.66  ? 81  LYS B CD  1 
ATOM 3938 C CE  . LYS D 4 81  ? 357.546 352.479 476.685 1.00 59.66  ? 81  LYS B CE  1 
ATOM 3939 N NZ  . LYS D 4 81  ? 358.904 352.435 476.112 1.00 59.66  ? 81  LYS B NZ  1 
ATOM 3940 N N   . LEU D 4 82  ? 352.683 351.239 472.447 1.00 67.22  ? 82  LEU B N   1 
ATOM 3941 C CA  . LEU D 4 82  ? 351.551 351.052 471.548 1.00 67.22  ? 82  LEU B CA  1 
ATOM 3942 C C   . LEU D 4 82  ? 350.919 349.664 471.460 1.00 67.22  ? 82  LEU B C   1 
ATOM 3943 O O   . LEU D 4 82  ? 349.686 349.602 471.404 1.00 67.22  ? 82  LEU B O   1 
ATOM 3944 C CB  . LEU D 4 82  ? 351.909 351.530 470.143 1.00 67.22  ? 82  LEU B CB  1 
ATOM 3945 C CG  . LEU D 4 82  ? 350.705 351.981 469.320 1.00 67.22  ? 82  LEU B CG  1 
ATOM 3946 C CD1 . LEU D 4 82  ? 349.701 352.740 470.157 1.00 67.22  ? 82  LEU B CD1 1 
ATOM 3947 C CD2 . LEU D 4 82  ? 351.178 352.856 468.197 1.00 67.22  ? 82  LEU B CD2 1 
ATOM 3948 N N   . PRO D 4 83  ? 351.649 348.521 471.411 1.00 69.02  ? 83  PRO B N   1 
ATOM 3949 C CA  . PRO D 4 83  ? 350.915 347.250 471.497 1.00 69.02  ? 83  PRO B CA  1 
ATOM 3950 C C   . PRO D 4 83  ? 350.715 346.793 472.927 1.00 69.02  ? 83  PRO B C   1 
ATOM 3951 O O   . PRO D 4 83  ? 350.813 345.605 473.231 1.00 69.02  ? 83  PRO B O   1 
ATOM 3952 C CB  . PRO D 4 83  ? 351.809 346.284 470.727 1.00 69.02  ? 83  PRO B CB  1 
ATOM 3953 C CG  . PRO D 4 83  ? 353.147 346.767 471.036 1.00 69.02  ? 83  PRO B CG  1 
ATOM 3954 C CD  . PRO D 4 83  ? 353.073 348.269 471.134 1.00 69.02  ? 83  PRO B CD  1 
ATOM 3955 N N   . ASP D 4 84  ? 350.426 347.736 473.798 1.00 75.96  ? 84  ASP B N   1 
ATOM 3956 C CA  . ASP D 4 84  ? 350.102 347.519 475.198 1.00 75.96  ? 84  ASP B CA  1 
ATOM 3957 C C   . ASP D 4 84  ? 348.927 348.358 475.658 1.00 75.96  ? 84  ASP B C   1 
ATOM 3958 O O   . ASP D 4 84  ? 348.207 347.942 476.569 1.00 75.96  ? 84  ASP B O   1 
ATOM 3959 C CB  . ASP D 4 84  ? 351.321 347.848 476.064 1.00 75.96  ? 84  ASP B CB  1 
ATOM 3960 C CG  . ASP D 4 84  ? 351.096 347.575 477.529 1.00 75.96  ? 84  ASP B CG  1 
ATOM 3961 O OD1 . ASP D 4 84  ? 350.371 346.617 477.860 1.00 75.96  ? 84  ASP B OD1 1 
ATOM 3962 O OD2 . ASP D 4 84  ? 351.628 348.337 478.357 1.00 75.96  ? 84  ASP B OD2 1 
ATOM 3963 N N   . ALA D 4 85  ? 348.671 349.502 475.027 1.00 78.65  ? 85  ALA B N   1 
ATOM 3964 C CA  . ALA D 4 85  ? 347.479 350.273 475.323 1.00 78.65  ? 85  ALA B CA  1 
ATOM 3965 C C   . ALA D 4 85  ? 346.226 349.569 474.842 1.00 78.65  ? 85  ALA B C   1 
ATOM 3966 O O   . ALA D 4 85  ? 345.144 349.824 475.372 1.00 78.65  ? 85  ALA B O   1 
ATOM 3967 C CB  . ALA D 4 85  ? 347.580 351.653 474.688 1.00 78.65  ? 85  ALA B CB  1 
ATOM 3968 N N   . LEU D 4 86  ? 346.352 348.683 473.858 1.00 81.66  ? 86  LEU B N   1 
ATOM 3969 C CA  . LEU D 4 86  ? 345.254 347.852 473.393 1.00 81.66  ? 86  LEU B CA  1 
ATOM 3970 C C   . LEU D 4 86  ? 345.335 346.438 473.947 1.00 81.66  ? 86  LEU B C   1 
ATOM 3971 O O   . LEU D 4 86  ? 345.041 345.479 473.237 1.00 81.66  ? 86  LEU B O   1 
ATOM 3972 C CB  . LEU D 4 86  ? 345.227 347.826 471.870 1.00 81.66  ? 86  LEU B CB  1 
ATOM 3973 C CG  . LEU D 4 86  ? 345.353 349.189 471.202 1.00 81.66  ? 86  LEU B CG  1 
ATOM 3974 C CD1 . LEU D 4 86  ? 345.361 349.043 469.708 1.00 81.66  ? 86  LEU B CD1 1 
ATOM 3975 C CD2 . LEU D 4 86  ? 344.220 350.080 471.619 1.00 81.66  ? 86  LEU B CD2 1 
ATOM 3976 N N   . SER D 4 87  ? 345.760 346.283 475.198 1.00 87.02  ? 87  SER B N   1 
ATOM 3977 C CA  . SER D 4 87  ? 345.846 344.955 475.786 1.00 87.02  ? 87  SER B CA  1 
ATOM 3978 C C   . SER D 4 87  ? 344.676 344.639 476.699 1.00 87.02  ? 87  SER B C   1 
ATOM 3979 O O   . SER D 4 87  ? 344.317 343.469 476.838 1.00 87.02  ? 87  SER B O   1 
ATOM 3980 C CB  . SER D 4 87  ? 347.139 344.810 476.573 1.00 87.02  ? 87  SER B CB  1 
ATOM 3981 O OG  . SER D 4 87  ? 346.981 345.366 477.862 1.00 87.02  ? 87  SER B OG  1 
ATOM 3982 N N   . GLN D 4 88  ? 344.085 345.640 477.339 1.00 89.49  ? 88  GLN B N   1 
ATOM 3983 C CA  . GLN D 4 88  ? 342.833 345.453 478.059 1.00 89.49  ? 88  GLN B CA  1 
ATOM 3984 C C   . GLN D 4 88  ? 341.645 345.895 477.223 1.00 89.49  ? 88  GLN B C   1 
ATOM 3985 O O   . GLN D 4 88  ? 340.541 346.045 477.757 1.00 89.49  ? 88  GLN B O   1 
ATOM 3986 C CB  . GLN D 4 88  ? 342.850 346.219 479.384 1.00 89.49  ? 88  GLN B CB  1 
ATOM 3987 C CG  . GLN D 4 88  ? 343.773 345.659 480.453 1.00 89.49  ? 88  GLN B CG  1 
ATOM 3988 C CD  . GLN D 4 88  ? 345.215 346.115 480.304 1.00 89.49  ? 88  GLN B CD  1 
ATOM 3989 O OE1 . GLN D 4 88  ? 345.601 346.682 479.282 1.00 89.49  ? 88  GLN B OE1 1 
ATOM 3990 N NE2 . GLN D 4 88  ? 346.016 345.880 481.336 1.00 89.49  ? 88  GLN B NE2 1 
ATOM 3991 N N   . MET D 4 89  ? 341.845 346.109 475.927 1.00 91.01  ? 89  MET B N   1 
ATOM 3992 C CA  . MET D 4 89  ? 340.828 346.719 475.083 1.00 91.01  ? 89  MET B CA  1 
ATOM 3993 C C   . MET D 4 89  ? 340.067 345.629 474.338 1.00 91.01  ? 89  MET B C   1 
ATOM 3994 O O   . MET D 4 89  ? 340.285 345.368 473.154 1.00 91.01  ? 89  MET B O   1 
ATOM 3995 C CB  . MET D 4 89  ? 341.465 347.715 474.126 1.00 91.01  ? 89  MET B CB  1 
ATOM 3996 C CG  . MET D 4 89  ? 341.931 349.013 474.756 1.00 91.01  ? 89  MET B CG  1 
ATOM 3997 S SD  . MET D 4 89  ? 340.586 350.085 475.280 1.00 91.01  ? 89  MET B SD  1 
ATOM 3998 C CE  . MET D 4 89  ? 340.623 349.871 477.058 1.00 91.01  ? 89  MET B CE  1 
ATOM 3999 N N   . GLY D 4 90  ? 339.158 344.985 475.063 1.00 99.91  ? 90  GLY B N   1 
ATOM 4000 C CA  . GLY D 4 90  ? 338.088 344.228 474.429 1.00 99.91  ? 90  GLY B CA  1 
ATOM 4001 C C   . GLY D 4 90  ? 338.566 342.960 473.757 1.00 99.91  ? 90  GLY B C   1 
ATOM 4002 O O   . GLY D 4 90  ? 339.422 342.236 474.275 1.00 99.91  ? 90  GLY B O   1 
ATOM 4003 N N   . LEU D 4 91  ? 338.014 342.700 472.569 1.00 103.98 ? 91  LEU B N   1 
ATOM 4004 C CA  . LEU D 4 91  ? 338.334 341.492 471.818 1.00 103.98 ? 91  LEU B CA  1 
ATOM 4005 C C   . LEU D 4 91  ? 339.749 341.535 471.254 1.00 103.98 ? 91  LEU B C   1 
ATOM 4006 O O   . LEU D 4 91  ? 340.330 340.480 470.982 1.00 103.98 ? 91  LEU B O   1 
ATOM 4007 C CB  . LEU D 4 91  ? 337.294 341.290 470.712 1.00 103.98 ? 91  LEU B CB  1 
ATOM 4008 C CG  . LEU D 4 91  ? 337.245 339.999 469.894 1.00 103.98 ? 91  LEU B CG  1 
ATOM 4009 C CD1 . LEU D 4 91  ? 336.559 338.906 470.691 1.00 103.98 ? 91  LEU B CD1 1 
ATOM 4010 C CD2 . LEU D 4 91  ? 336.486 340.232 468.612 1.00 103.98 ? 91  LEU B CD2 1 
ATOM 4011 N N   . PHE D 4 92  ? 340.320 342.732 471.080 1.00 96.84  ? 92  PHE B N   1 
ATOM 4012 C CA  . PHE D 4 92  ? 341.743 342.838 470.787 1.00 96.84  ? 92  PHE B CA  1 
ATOM 4013 C C   . PHE D 4 92  ? 342.587 342.331 471.939 1.00 96.84  ? 92  PHE B C   1 
ATOM 4014 O O   . PHE D 4 92  ? 343.612 341.695 471.704 1.00 96.84  ? 92  PHE B O   1 
ATOM 4015 C CB  . PHE D 4 92  ? 342.124 344.281 470.474 1.00 96.84  ? 92  PHE B CB  1 
ATOM 4016 C CG  . PHE D 4 92  ? 343.366 344.418 469.643 1.00 96.84  ? 92  PHE B CG  1 
ATOM 4017 C CD1 . PHE D 4 92  ? 343.312 344.318 468.270 1.00 96.84  ? 92  PHE B CD1 1 
ATOM 4018 C CD2 . PHE D 4 92  ? 344.584 344.673 470.235 1.00 96.84  ? 92  PHE B CD2 1 
ATOM 4019 C CE1 . PHE D 4 92  ? 344.457 344.457 467.505 1.00 96.84  ? 92  PHE B CE1 1 
ATOM 4020 C CE2 . PHE D 4 92  ? 345.730 344.814 469.478 1.00 96.84  ? 92  PHE B CE2 1 
ATOM 4021 C CZ  . PHE D 4 92  ? 345.665 344.706 468.113 1.00 96.84  ? 92  PHE B CZ  1 
ATOM 4022 N N   . GLY D 4 93  ? 342.164 342.571 473.178 1.00 100.50 ? 93  GLY B N   1 
ATOM 4023 C CA  . GLY D 4 93  ? 342.851 341.977 474.304 1.00 100.50 ? 93  GLY B CA  1 
ATOM 4024 C C   . GLY D 4 93  ? 342.602 340.497 474.469 1.00 100.50 ? 93  GLY B C   1 
ATOM 4025 O O   . GLY D 4 93  ? 343.449 339.798 475.032 1.00 100.50 ? 93  GLY B O   1 
ATOM 4026 N N   . GLN D 4 94  ? 341.459 340.002 473.997 1.00 106.59 ? 94  GLN B N   1 
ATOM 4027 C CA  . GLN D 4 94  ? 341.205 338.567 473.983 1.00 106.59 ? 94  GLN B CA  1 
ATOM 4028 C C   . GLN D 4 94  ? 342.036 337.855 472.931 1.00 106.59 ? 94  GLN B C   1 
ATOM 4029 O O   . GLN D 4 94  ? 342.475 336.726 473.156 1.00 106.59 ? 94  GLN B O   1 
ATOM 4030 C CB  . GLN D 4 94  ? 339.724 338.281 473.733 1.00 106.59 ? 94  GLN B CB  1 
ATOM 4031 C CG  . GLN D 4 94  ? 338.777 339.033 474.631 1.00 106.59 ? 94  GLN B CG  1 
ATOM 4032 C CD  . GLN D 4 94  ? 337.534 338.235 474.927 1.00 106.59 ? 94  GLN B CD  1 
ATOM 4033 O OE1 . GLN D 4 94  ? 337.297 337.194 474.315 1.00 106.59 ? 94  GLN B OE1 1 
ATOM 4034 N NE2 . GLN D 4 94  ? 336.726 338.716 475.865 1.00 106.59 ? 94  GLN B NE2 1 
ATOM 4035 N N   . ASN D 4 95  ? 342.266 338.496 471.787 1.00 107.17 ? 95  ASN B N   1 
ATOM 4036 C CA  . ASN D 4 95  ? 343.109 337.910 470.759 1.00 107.17 ? 95  ASN B CA  1 
ATOM 4037 C C   . ASN D 4 95  ? 344.586 337.907 471.123 1.00 107.17 ? 95  ASN B C   1 
ATOM 4038 O O   . ASN D 4 95  ? 345.363 337.236 470.440 1.00 107.17 ? 95  ASN B O   1 
ATOM 4039 C CB  . ASN D 4 95  ? 342.923 338.636 469.427 1.00 107.17 ? 95  ASN B CB  1 
ATOM 4040 C CG  . ASN D 4 95  ? 341.740 338.109 468.633 1.00 107.17 ? 95  ASN B CG  1 
ATOM 4041 O OD1 . ASN D 4 95  ? 340.765 337.622 469.202 1.00 107.17 ? 95  ASN B OD1 1 
ATOM 4042 N ND2 . ASN D 4 95  ? 341.829 338.193 467.310 1.00 107.17 ? 95  ASN B ND2 1 
ATOM 4043 N N   . MET D 4 96  ? 344.999 338.625 472.171 1.00 105.57 ? 96  MET B N   1 
ATOM 4044 C CA  . MET D 4 96  ? 346.402 338.584 472.569 1.00 105.57 ? 96  MET B CA  1 
ATOM 4045 C C   . MET D 4 96  ? 346.713 337.412 473.484 1.00 105.57 ? 96  MET B C   1 
ATOM 4046 O O   . MET D 4 96  ? 347.782 336.811 473.361 1.00 105.57 ? 96  MET B O   1 
ATOM 4047 C CB  . MET D 4 96  ? 346.808 339.889 473.249 1.00 105.57 ? 96  MET B CB  1 
ATOM 4048 C CG  . MET D 4 96  ? 346.762 341.098 472.342 1.00 105.57 ? 96  MET B CG  1 
ATOM 4049 S SD  . MET D 4 96  ? 347.508 340.790 470.736 1.00 105.57 ? 96  MET B SD  1 
ATOM 4050 C CE  . MET D 4 96  ? 346.077 340.879 469.669 1.00 105.57 ? 96  MET B CE  1 
ATOM 4051 N N   . GLN D 4 97  ? 345.803 337.053 474.381 1.00 106.83 ? 97  GLN B N   1 
ATOM 4052 C CA  . GLN D 4 97  ? 346.045 335.925 475.270 1.00 106.83 ? 97  GLN B CA  1 
ATOM 4053 C C   . GLN D 4 97  ? 345.881 334.593 474.563 1.00 106.83 ? 97  GLN B C   1 
ATOM 4054 O O   . GLN D 4 97  ? 346.274 333.553 475.102 1.00 106.83 ? 97  GLN B O   1 
ATOM 4055 C CB  . GLN D 4 97  ? 345.097 335.980 476.468 1.00 106.83 ? 97  GLN B CB  1 
ATOM 4056 C CG  . GLN D 4 97  ? 345.148 337.282 477.225 1.00 106.83 ? 97  GLN B CG  1 
ATOM 4057 C CD  . GLN D 4 97  ? 344.922 337.095 478.699 1.00 106.83 ? 97  GLN B CD  1 
ATOM 4058 O OE1 . GLN D 4 97  ? 343.978 336.423 479.111 1.00 106.83 ? 97  GLN B OE1 1 
ATOM 4059 N NE2 . GLN D 4 97  ? 345.784 337.695 479.509 1.00 106.83 ? 97  GLN B NE2 1 
ATOM 4060 N N   . TYR D 4 98  ? 345.308 334.605 473.369 1.00 110.52 ? 98  TYR B N   1 
ATOM 4061 C CA  . TYR D 4 98  ? 345.072 333.368 472.650 1.00 110.52 ? 98  TYR B CA  1 
ATOM 4062 C C   . TYR D 4 98  ? 346.185 333.111 471.643 1.00 110.52 ? 98  TYR B C   1 
ATOM 4063 O O   . TYR D 4 98  ? 346.235 332.039 471.033 1.00 110.52 ? 98  TYR B O   1 
ATOM 4064 C CB  . TYR D 4 98  ? 343.715 333.425 471.943 1.00 110.52 ? 98  TYR B CB  1 
ATOM 4065 C CG  . TYR D 4 98  ? 342.482 333.182 472.804 1.00 110.52 ? 98  TYR B CG  1 
ATOM 4066 C CD1 . TYR D 4 98  ? 342.366 333.715 474.087 1.00 110.52 ? 98  TYR B CD1 1 
ATOM 4067 C CD2 . TYR D 4 98  ? 341.415 332.441 472.312 1.00 110.52 ? 98  TYR B CD2 1 
ATOM 4068 C CE1 . TYR D 4 98  ? 341.237 333.506 474.857 1.00 110.52 ? 98  TYR B CE1 1 
ATOM 4069 C CE2 . TYR D 4 98  ? 340.279 332.221 473.077 1.00 110.52 ? 98  TYR B CE2 1 
ATOM 4070 C CZ  . TYR D 4 98  ? 340.198 332.757 474.349 1.00 110.52 ? 98  TYR B CZ  1 
ATOM 4071 O OH  . TYR D 4 98  ? 339.075 332.544 475.115 1.00 110.52 ? 98  TYR B OH  1 
ATOM 4072 N N   . HIS D 4 99  ? 347.069 334.085 471.437 1.00 108.67 ? 99  HIS B N   1 
ATOM 4073 C CA  . HIS D 4 99  ? 348.054 334.031 470.367 1.00 108.67 ? 99  HIS B CA  1 
ATOM 4074 C C   . HIS D 4 99  ? 349.442 334.437 470.857 1.00 108.67 ? 99  HIS B C   1 
ATOM 4075 O O   . HIS D 4 99  ? 349.607 335.498 471.465 1.00 108.67 ? 99  HIS B O   1 
ATOM 4076 C CB  . HIS D 4 99  ? 347.632 334.944 469.220 1.00 108.67 ? 99  HIS B CB  1 
ATOM 4077 C CG  . HIS D 4 99  ? 346.247 334.688 468.711 1.00 108.67 ? 99  HIS B CG  1 
ATOM 4078 N ND1 . HIS D 4 99  ? 345.119 335.152 469.350 1.00 108.67 ? 99  HIS B ND1 1 
ATOM 4079 C CD2 . HIS D 4 99  ? 345.810 334.034 467.609 1.00 108.67 ? 99  HIS B CD2 1 
ATOM 4080 C CE1 . HIS D 4 99  ? 344.047 334.789 468.670 1.00 108.67 ? 99  HIS B CE1 1 
ATOM 4081 N NE2 . HIS D 4 99  ? 344.439 334.111 467.608 1.00 108.67 ? 99  HIS B NE2 1 
ATOM 4082 N N   . TYR D 4 100 ? 350.449 333.610 470.536 1.00 106.33 ? 100 TYR B N   1 
ATOM 4083 C CA  . TYR D 4 100 ? 351.821 333.821 471.011 1.00 106.33 ? 100 TYR B CA  1 
ATOM 4084 C C   . TYR D 4 100 ? 352.536 334.924 470.229 1.00 106.33 ? 100 TYR B C   1 
ATOM 4085 O O   . TYR D 4 100 ? 353.408 335.611 470.770 1.00 106.33 ? 100 TYR B O   1 
ATOM 4086 C CB  . TYR D 4 100 ? 352.609 332.501 470.926 1.00 106.33 ? 100 TYR B CB  1 
ATOM 4087 C CG  . TYR D 4 100 ? 353.943 332.424 471.689 1.00 106.33 ? 100 TYR B CG  1 
ATOM 4088 C CD1 . TYR D 4 100 ? 353.985 332.076 473.039 1.00 106.33 ? 100 TYR B CD1 1 
ATOM 4089 C CD2 . TYR D 4 100 ? 355.160 332.653 471.043 1.00 106.33 ? 100 TYR B CD2 1 
ATOM 4090 C CE1 . TYR D 4 100 ? 355.208 331.984 473.724 1.00 106.33 ? 100 TYR B CE1 1 
ATOM 4091 C CE2 . TYR D 4 100 ? 356.380 332.568 471.720 1.00 106.33 ? 100 TYR B CE2 1 
ATOM 4092 C CZ  . TYR D 4 100 ? 356.395 332.230 473.058 1.00 106.33 ? 100 TYR B CZ  1 
ATOM 4093 O OH  . TYR D 4 100 ? 357.589 332.142 473.734 1.00 106.33 ? 100 TYR B OH  1 
ATOM 4094 N N   . LEU D 4 101 ? 352.176 335.110 468.960 1.00 101.64 ? 101 LEU B N   1 
ATOM 4095 C CA  . LEU D 4 101 ? 352.882 335.967 468.019 1.00 101.64 ? 101 LEU B CA  1 
ATOM 4096 C C   . LEU D 4 101 ? 351.913 336.920 467.313 1.00 101.64 ? 101 LEU B C   1 
ATOM 4097 O O   . LEU D 4 101 ? 350.690 336.775 467.400 1.00 101.64 ? 101 LEU B O   1 
ATOM 4098 C CB  . LEU D 4 101 ? 353.632 335.087 467.020 1.00 101.64 ? 101 LEU B CB  1 
ATOM 4099 C CG  . LEU D 4 101 ? 354.750 334.180 467.526 1.00 101.64 ? 101 LEU B CG  1 
ATOM 4100 C CD1 . LEU D 4 101 ? 355.541 333.630 466.378 1.00 101.64 ? 101 LEU B CD1 1 
ATOM 4101 C CD2 . LEU D 4 101 ? 355.664 334.971 468.410 1.00 101.64 ? 101 LEU B CD2 1 
ATOM 4102 N N   . GLY D 4 102 ? 352.465 337.888 466.594 1.00 93.70  ? 102 GLY B N   1 
ATOM 4103 C CA  . GLY D 4 102 ? 351.654 338.786 465.797 1.00 93.70  ? 102 GLY B CA  1 
ATOM 4104 C C   . GLY D 4 102 ? 352.454 339.934 465.225 1.00 93.70  ? 102 GLY B C   1 
ATOM 4105 O O   . GLY D 4 102 ? 353.526 340.290 465.712 1.00 93.70  ? 102 GLY B O   1 
ATOM 4106 N N   . ARG D 4 103 ? 351.904 340.529 464.162 1.00 89.77  ? 103 ARG B N   1 
ATOM 4107 C CA  . ARG D 4 103 ? 352.480 341.714 463.537 1.00 89.77  ? 103 ARG B CA  1 
ATOM 4108 C C   . ARG D 4 103 ? 351.371 342.642 463.070 1.00 89.77  ? 103 ARG B C   1 
ATOM 4109 O O   . ARG D 4 103 ? 350.454 342.209 462.374 1.00 89.77  ? 103 ARG B O   1 
ATOM 4110 C CB  . ARG D 4 103 ? 353.377 341.343 462.363 1.00 89.77  ? 103 ARG B CB  1 
ATOM 4111 C CG  . ARG D 4 103 ? 352.877 340.220 461.503 1.00 89.77  ? 103 ARG B CG  1 
ATOM 4112 C CD  . ARG D 4 103 ? 353.684 340.161 460.222 1.00 89.77  ? 103 ARG B CD  1 
ATOM 4113 N NE  . ARG D 4 103 ? 353.539 341.375 459.427 1.00 89.77  ? 103 ARG B NE  1 
ATOM 4114 C CZ  . ARG D 4 103 ? 354.509 341.915 458.700 1.00 89.77  ? 103 ARG B CZ  1 
ATOM 4115 N NH1 . ARG D 4 103 ? 355.710 341.363 458.675 1.00 89.77  ? 103 ARG B NH1 1 
ATOM 4116 N NH2 . ARG D 4 103 ? 354.282 343.020 458.007 1.00 89.77  ? 103 ARG B NH2 1 
ATOM 4117 N N   . THR D 4 104 ? 351.463 343.916 463.439 1.00 85.04  ? 104 THR B N   1 
ATOM 4118 C CA  . THR D 4 104 ? 350.355 344.853 463.316 1.00 85.04  ? 104 THR B CA  1 
ATOM 4119 C C   . THR D 4 104 ? 350.861 346.247 462.949 1.00 85.04  ? 104 THR B C   1 
ATOM 4120 O O   . THR D 4 104 ? 351.813 346.758 463.540 1.00 85.04  ? 104 THR B O   1 
ATOM 4121 C CB  . THR D 4 104 ? 349.560 344.921 464.632 1.00 85.04  ? 104 THR B CB  1 
ATOM 4122 O OG1 . THR D 4 104 ? 349.352 343.605 465.155 1.00 85.04  ? 104 THR B OG1 1 
ATOM 4123 C CG2 . THR D 4 104 ? 348.225 345.589 464.426 1.00 85.04  ? 104 THR B CG2 1 
ATOM 4124 N N   . GLY D 4 105 ? 350.200 346.876 461.971 1.00 78.80  ? 105 GLY B N   1 
ATOM 4125 C CA  . GLY D 4 105 ? 350.376 348.284 461.695 1.00 78.80  ? 105 GLY B CA  1 
ATOM 4126 C C   . GLY D 4 105 ? 349.260 349.072 462.363 1.00 78.80  ? 105 GLY B C   1 
ATOM 4127 O O   . GLY D 4 105 ? 348.280 348.500 462.841 1.00 78.80  ? 105 GLY B O   1 
ATOM 4128 N N   . TYR D 4 106 ? 349.409 350.394 462.396 1.00 69.65  ? 106 TYR B N   1 
ATOM 4129 C CA  . TYR D 4 106 ? 348.482 351.220 463.153 1.00 69.65  ? 106 TYR B CA  1 
ATOM 4130 C C   . TYR D 4 106 ? 348.072 352.460 462.379 1.00 69.65  ? 106 TYR B C   1 
ATOM 4131 O O   . TYR D 4 106 ? 348.644 352.794 461.345 1.00 69.65  ? 106 TYR B O   1 
ATOM 4132 C CB  . TYR D 4 106 ? 349.083 351.646 464.480 1.00 69.65  ? 106 TYR B CB  1 
ATOM 4133 C CG  . TYR D 4 106 ? 349.316 350.506 465.411 1.00 69.65  ? 106 TYR B CG  1 
ATOM 4134 C CD1 . TYR D 4 106 ? 348.263 349.756 465.883 1.00 69.65  ? 106 TYR B CD1 1 
ATOM 4135 C CD2 . TYR D 4 106 ? 350.591 350.177 465.820 1.00 69.65  ? 106 TYR B CD2 1 
ATOM 4136 C CE1 . TYR D 4 106 ? 348.470 348.709 466.735 1.00 69.65  ? 106 TYR B CE1 1 
ATOM 4137 C CE2 . TYR D 4 106 ? 350.811 349.134 466.672 1.00 69.65  ? 106 TYR B CE2 1 
ATOM 4138 C CZ  . TYR D 4 106 ? 349.746 348.403 467.124 1.00 69.65  ? 106 TYR B CZ  1 
ATOM 4139 O OH  . TYR D 4 106 ? 349.965 347.358 467.979 1.00 69.65  ? 106 TYR B OH  1 
ATOM 4140 N N   . THR D 4 107 ? 347.061 353.140 462.913 1.00 65.18  ? 107 THR B N   1 
ATOM 4141 C CA  . THR D 4 107 ? 346.596 354.421 462.391 1.00 65.18  ? 107 THR B CA  1 
ATOM 4142 C C   . THR D 4 107 ? 346.121 355.232 463.582 1.00 65.18  ? 107 THR B C   1 
ATOM 4143 O O   . THR D 4 107 ? 345.171 354.833 464.250 1.00 65.18  ? 107 THR B O   1 
ATOM 4144 C CB  . THR D 4 107 ? 345.472 354.241 461.385 1.00 65.18  ? 107 THR B CB  1 
ATOM 4145 O OG1 . THR D 4 107 ? 345.946 353.507 460.255 1.00 65.18  ? 107 THR B OG1 1 
ATOM 4146 C CG2 . THR D 4 107 ? 344.973 355.576 460.924 1.00 65.18  ? 107 THR B CG2 1 
ATOM 4147 N N   . ILE D 4 108 ? 346.766 356.357 463.851 1.00 60.01  ? 108 ILE B N   1 
ATOM 4148 C CA  . ILE D 4 108 ? 346.556 357.110 465.079 1.00 60.01  ? 108 ILE B CA  1 
ATOM 4149 C C   . ILE D 4 108 ? 345.933 358.454 464.741 1.00 60.01  ? 108 ILE B C   1 
ATOM 4150 O O   . ILE D 4 108 ? 346.472 359.199 463.919 1.00 60.01  ? 108 ILE B O   1 
ATOM 4151 C CB  . ILE D 4 108 ? 347.876 357.296 465.839 1.00 60.01  ? 108 ILE B CB  1 
ATOM 4152 C CG1 . ILE D 4 108 ? 348.524 355.940 466.080 1.00 60.01  ? 108 ILE B CG1 1 
ATOM 4153 C CG2 . ILE D 4 108 ? 347.636 357.990 467.140 1.00 60.01  ? 108 ILE B CG2 1 
ATOM 4154 C CD1 . ILE D 4 108 ? 349.958 356.014 466.456 1.00 60.01  ? 108 ILE B CD1 1 
ATOM 4155 N N   . HIS D 4 109 ? 344.805 358.764 465.375 1.00 62.94  ? 109 HIS B N   1 
ATOM 4156 C CA  . HIS D 4 109 ? 344.125 360.044 465.232 1.00 62.94  ? 109 HIS B CA  1 
ATOM 4157 C C   . HIS D 4 109 ? 344.201 360.777 466.558 1.00 62.94  ? 109 HIS B C   1 
ATOM 4158 O O   . HIS D 4 109 ? 343.597 360.341 467.539 1.00 62.94  ? 109 HIS B O   1 
ATOM 4159 C CB  . HIS D 4 109 ? 342.658 359.861 464.848 1.00 62.94  ? 109 HIS B CB  1 
ATOM 4160 C CG  . HIS D 4 109 ? 342.434 359.446 463.431 1.00 62.94  ? 109 HIS B CG  1 
ATOM 4161 N ND1 . HIS D 4 109 ? 342.169 358.145 463.072 1.00 62.94  ? 109 HIS B ND1 1 
ATOM 4162 C CD2 . HIS D 4 109 ? 342.395 360.166 462.287 1.00 62.94  ? 109 HIS B CD2 1 
ATOM 4163 C CE1 . HIS D 4 109 ? 341.999 358.076 461.765 1.00 62.94  ? 109 HIS B CE1 1 
ATOM 4164 N NE2 . HIS D 4 109 ? 342.132 359.290 461.264 1.00 62.94  ? 109 HIS B NE2 1 
ATOM 4165 N N   . VAL D 4 110 ? 344.915 361.894 466.588 1.00 57.45  ? 110 VAL B N   1 
ATOM 4166 C CA  . VAL D 4 110 ? 345.025 362.726 467.778 1.00 57.45  ? 110 VAL B CA  1 
ATOM 4167 C C   . VAL D 4 110 ? 344.367 364.055 467.484 1.00 57.45  ? 110 VAL B C   1 
ATOM 4168 O O   . VAL D 4 110 ? 344.770 364.748 466.547 1.00 57.45  ? 110 VAL B O   1 
ATOM 4169 C CB  . VAL D 4 110 ? 346.485 362.953 468.190 1.00 57.45  ? 110 VAL B CB  1 
ATOM 4170 C CG1 . VAL D 4 110 ? 346.555 363.968 469.294 1.00 57.45  ? 110 VAL B CG1 1 
ATOM 4171 C CG2 . VAL D 4 110 ? 347.098 361.670 468.634 1.00 57.45  ? 110 VAL B CG2 1 
ATOM 4172 N N   . GLN D 4 111 ? 343.363 364.415 468.274 1.00 61.83  ? 111 GLN B N   1 
ATOM 4173 C CA  . GLN D 4 111 ? 342.799 365.750 468.162 1.00 61.83  ? 111 GLN B CA  1 
ATOM 4174 C C   . GLN D 4 111 ? 342.541 366.303 469.550 1.00 61.83  ? 111 GLN B C   1 
ATOM 4175 O O   . GLN D 4 111 ? 342.124 365.574 470.451 1.00 61.83  ? 111 GLN B O   1 
ATOM 4176 C CB  . GLN D 4 111 ? 341.522 365.756 467.327 1.00 61.83  ? 111 GLN B CB  1 
ATOM 4177 C CG  . GLN D 4 111 ? 340.370 364.976 467.857 1.00 61.83  ? 111 GLN B CG  1 
ATOM 4178 C CD  . GLN D 4 111 ? 339.063 365.562 467.400 1.00 61.83  ? 111 GLN B CD  1 
ATOM 4179 O OE1 . GLN D 4 111 ? 339.043 366.519 466.629 1.00 61.83  ? 111 GLN B OE1 1 
ATOM 4180 N NE2 . GLN D 4 111 ? 337.960 365.020 467.903 1.00 61.83  ? 111 GLN B NE2 1 
ATOM 4181 N N   . CYS D 4 112 ? 342.856 367.574 469.736 1.00 63.27  ? 112 CYS B N   1 
ATOM 4182 C CA  . CYS D 4 112 ? 342.462 368.319 470.914 1.00 63.27  ? 112 CYS B CA  1 
ATOM 4183 C C   . CYS D 4 112 ? 341.563 369.441 470.448 1.00 63.27  ? 112 CYS B C   1 
ATOM 4184 O O   . CYS D 4 112 ? 341.748 369.966 469.354 1.00 63.27  ? 112 CYS B O   1 
ATOM 4185 C CB  . CYS D 4 112 ? 343.659 368.879 471.673 1.00 63.27  ? 112 CYS B CB  1 
ATOM 4186 S SG  . CYS D 4 112 ? 344.583 370.159 470.830 1.00 63.27  ? 112 CYS B SG  1 
ATOM 4187 N N   . ASN D 4 113 ? 340.579 369.787 471.251 1.00 62.86  ? 113 ASN B N   1 
ATOM 4188 C CA  . ASN D 4 113 ? 339.571 370.748 470.836 1.00 62.86  ? 113 ASN B CA  1 
ATOM 4189 C C   . ASN D 4 113 ? 339.518 371.903 471.822 1.00 62.86  ? 113 ASN B C   1 
ATOM 4190 O O   . ASN D 4 113 ? 339.003 371.769 472.934 1.00 62.86  ? 113 ASN B O   1 
ATOM 4191 C CB  . ASN D 4 113 ? 338.223 370.061 470.645 1.00 62.86  ? 113 ASN B CB  1 
ATOM 4192 C CG  . ASN D 4 113 ? 337.903 369.094 471.739 1.00 62.86  ? 113 ASN B CG  1 
ATOM 4193 O OD1 . ASN D 4 113 ? 338.626 368.982 472.718 1.00 62.86  ? 113 ASN B OD1 1 
ATOM 4194 N ND2 . ASN D 4 113 ? 336.824 368.356 471.563 1.00 62.86  ? 113 ASN B ND2 1 
ATOM 4195 N N   . ALA D 4 114 ? 340.069 373.029 471.399 1.00 60.58  ? 114 ALA B N   1 
ATOM 4196 C CA  . ALA D 4 114 ? 340.059 374.271 472.138 1.00 60.58  ? 114 ALA B CA  1 
ATOM 4197 C C   . ALA D 4 114 ? 339.391 375.336 471.292 1.00 60.58  ? 114 ALA B C   1 
ATOM 4198 O O   . ALA D 4 114 ? 339.079 375.122 470.120 1.00 60.58  ? 114 ALA B O   1 
ATOM 4199 C CB  . ALA D 4 114 ? 341.471 374.715 472.494 1.00 60.58  ? 114 ALA B CB  1 
ATOM 4200 N N   . SER D 4 115 ? 339.204 376.500 471.891 1.00 59.49  ? 115 SER B N   1 
ATOM 4201 C CA  . SER D 4 115 ? 338.535 377.607 471.229 1.00 59.49  ? 115 SER B CA  1 
ATOM 4202 C C   . SER D 4 115 ? 339.527 378.366 470.356 1.00 59.49  ? 115 SER B C   1 
ATOM 4203 O O   . SER D 4 115 ? 340.634 377.903 470.078 1.00 59.49  ? 115 SER B O   1 
ATOM 4204 C CB  . SER D 4 115 ? 337.900 378.512 472.268 1.00 59.49  ? 115 SER B CB  1 
ATOM 4205 O OG  . SER D 4 115 ? 338.788 378.699 473.348 1.00 59.49  ? 115 SER B OG  1 
ATOM 4206 N N   . LYS D 4 116 ? 339.125 379.542 469.893 1.00 60.56  ? 116 LYS B N   1 
ATOM 4207 C CA  . LYS D 4 116 ? 340.045 380.463 469.247 1.00 60.56  ? 116 LYS B CA  1 
ATOM 4208 C C   . LYS D 4 116 ? 340.654 381.440 470.228 1.00 60.56  ? 116 LYS B C   1 
ATOM 4209 O O   . LYS D 4 116 ? 341.342 382.371 469.807 1.00 60.56  ? 116 LYS B O   1 
ATOM 4210 C CB  . LYS D 4 116 ? 339.337 381.234 468.137 1.00 60.56  ? 116 LYS B CB  1 
ATOM 4211 C CG  . LYS D 4 116 ? 339.362 380.537 466.799 1.00 60.56  ? 116 LYS B CG  1 
ATOM 4212 C CD  . LYS D 4 116 ? 337.982 380.500 466.180 1.00 60.56  ? 116 LYS B CD  1 
ATOM 4213 C CE  . LYS D 4 116 ? 337.658 381.808 465.485 1.00 60.56  ? 116 LYS B CE  1 
ATOM 4214 N NZ  . LYS D 4 116 ? 336.282 381.809 464.915 1.00 60.56  ? 116 LYS B NZ  1 
ATOM 4215 N N   . PHE D 4 117 ? 340.409 381.259 471.517 1.00 57.43  ? 117 PHE B N   1 
ATOM 4216 C CA  . PHE D 4 117 ? 340.937 382.139 472.540 1.00 57.43  ? 117 PHE B CA  1 
ATOM 4217 C C   . PHE D 4 117 ? 342.021 381.471 473.367 1.00 57.43  ? 117 PHE B C   1 
ATOM 4218 O O   . PHE D 4 117 ? 342.600 382.118 474.243 1.00 57.43  ? 117 PHE B O   1 
ATOM 4219 C CB  . PHE D 4 117 ? 339.802 382.630 473.442 1.00 57.43  ? 117 PHE B CB  1 
ATOM 4220 C CG  . PHE D 4 117 ? 338.891 383.621 472.778 1.00 57.43  ? 117 PHE B CG  1 
ATOM 4221 C CD1 . PHE D 4 117 ? 337.877 383.207 471.941 1.00 57.43  ? 117 PHE B CD1 1 
ATOM 4222 C CD2 . PHE D 4 117 ? 339.047 384.966 472.998 1.00 57.43  ? 117 PHE B CD2 1 
ATOM 4223 C CE1 . PHE D 4 117 ? 337.054 384.121 471.329 1.00 57.43  ? 117 PHE B CE1 1 
ATOM 4224 C CE2 . PHE D 4 117 ? 338.225 385.878 472.391 1.00 57.43  ? 117 PHE B CE2 1 
ATOM 4225 C CZ  . PHE D 4 117 ? 337.229 385.453 471.559 1.00 57.43  ? 117 PHE B CZ  1 
ATOM 4226 N N   . HIS D 4 118 ? 342.302 380.195 473.113 1.00 55.57  ? 118 HIS B N   1 
ATOM 4227 C CA  . HIS D 4 118 ? 343.426 379.478 473.687 1.00 55.57  ? 118 HIS B CA  1 
ATOM 4228 C C   . HIS D 4 118 ? 344.604 379.521 472.726 1.00 55.57  ? 118 HIS B C   1 
ATOM 4229 O O   . HIS D 4 118 ? 344.453 379.778 471.533 1.00 55.57  ? 118 HIS B O   1 
ATOM 4230 C CB  . HIS D 4 118 ? 343.052 378.028 473.968 1.00 55.57  ? 118 HIS B CB  1 
ATOM 4231 C CG  . HIS D 4 118 ? 342.053 377.850 475.063 1.00 55.57  ? 118 HIS B CG  1 
ATOM 4232 N ND1 . HIS D 4 118 ? 340.714 378.122 474.903 1.00 55.57  ? 118 HIS B ND1 1 
ATOM 4233 C CD2 . HIS D 4 118 ? 342.192 377.381 476.323 1.00 55.57  ? 118 HIS B CD2 1 
ATOM 4234 C CE1 . HIS D 4 118 ? 340.076 377.847 476.025 1.00 55.57  ? 118 HIS B CE1 1 
ATOM 4235 N NE2 . HIS D 4 118 ? 340.950 377.395 476.901 1.00 55.57  ? 118 HIS B NE2 1 
ATOM 4236 N N   . GLN D 4 119 ? 345.793 379.238 473.252 1.00 55.05  ? 119 GLN B N   1 
ATOM 4237 C CA  . GLN D 4 119 ? 346.988 379.227 472.423 1.00 55.05  ? 119 GLN B CA  1 
ATOM 4238 C C   . GLN D 4 119 ? 347.976 378.198 472.950 1.00 55.05  ? 119 GLN B C   1 
ATOM 4239 O O   . GLN D 4 119 ? 348.096 377.995 474.157 1.00 55.05  ? 119 GLN B O   1 
ATOM 4240 C CB  . GLN D 4 119 ? 347.635 380.600 472.379 1.00 55.05  ? 119 GLN B CB  1 
ATOM 4241 C CG  . GLN D 4 119 ? 347.738 381.239 473.714 1.00 55.05  ? 119 GLN B CG  1 
ATOM 4242 C CD  . GLN D 4 119 ? 348.344 382.603 473.644 1.00 55.05  ? 119 GLN B CD  1 
ATOM 4243 O OE1 . GLN D 4 119 ? 349.457 382.823 474.105 1.00 55.05  ? 119 GLN B OE1 1 
ATOM 4244 N NE2 . GLN D 4 119 ? 347.615 383.536 473.073 1.00 55.05  ? 119 GLN B NE2 1 
ATOM 4245 N N   . GLY D 4 120 ? 348.683 377.559 472.034 1.00 53.09  ? 120 GLY B N   1 
ATOM 4246 C CA  . GLY D 4 120 ? 349.618 376.514 472.391 1.00 53.09  ? 120 GLY B CA  1 
ATOM 4247 C C   . GLY D 4 120 ? 350.153 375.837 471.150 1.00 53.09  ? 120 GLY B C   1 
ATOM 4248 O O   . GLY D 4 120 ? 349.871 376.243 470.028 1.00 53.09  ? 120 GLY B O   1 
ATOM 4249 N N   . CYS D 4 121 ? 350.937 374.785 471.383 1.00 51.52  ? 121 CYS B N   1 
ATOM 4250 C CA  . CYS D 4 121 ? 351.564 374.034 470.301 1.00 51.52  ? 121 CYS B CA  1 
ATOM 4251 C C   . CYS D 4 121 ? 352.016 372.682 470.824 1.00 51.52  ? 121 CYS B C   1 
ATOM 4252 O O   . CYS D 4 121 ? 352.726 372.618 471.827 1.00 51.52  ? 121 CYS B O   1 
ATOM 4253 C CB  . CYS D 4 121 ? 352.759 374.786 469.728 1.00 51.52  ? 121 CYS B CB  1 
ATOM 4254 S SG  . CYS D 4 121 ? 353.460 374.034 468.273 1.00 51.52  ? 121 CYS B SG  1 
ATOM 4255 N N   . LEU D 4 122 ? 351.623 371.612 470.143 1.00 50.46  ? 122 LEU B N   1 
ATOM 4256 C CA  . LEU D 4 122 ? 351.973 370.254 470.527 1.00 50.46  ? 122 LEU B CA  1 
ATOM 4257 C C   . LEU D 4 122 ? 352.775 369.575 469.429 1.00 50.46  ? 122 LEU B C   1 
ATOM 4258 O O   . LEU D 4 122 ? 352.609 369.851 468.244 1.00 50.46  ? 122 LEU B O   1 
ATOM 4259 C CB  . LEU D 4 122 ? 350.725 369.422 470.807 1.00 50.46  ? 122 LEU B CB  1 
ATOM 4260 C CG  . LEU D 4 122 ? 349.845 369.689 472.008 1.00 50.46  ? 122 LEU B CG  1 
ATOM 4261 C CD1 . LEU D 4 122 ? 348.574 368.945 471.803 1.00 50.46  ? 122 LEU B CD1 1 
ATOM 4262 C CD2 . LEU D 4 122 ? 350.506 369.213 473.246 1.00 50.46  ? 122 LEU B CD2 1 
ATOM 4263 N N   . LEU D 4 123 ? 353.632 368.649 469.844 1.00 49.81  ? 123 LEU B N   1 
ATOM 4264 C CA  . LEU D 4 123 ? 354.358 367.776 468.934 1.00 49.81  ? 123 LEU B CA  1 
ATOM 4265 C C   . LEU D 4 123 ? 353.896 366.355 469.180 1.00 49.81  ? 123 LEU B C   1 
ATOM 4266 O O   . LEU D 4 123 ? 354.038 365.844 470.291 1.00 49.81  ? 123 LEU B O   1 
ATOM 4267 C CB  . LEU D 4 123 ? 355.866 367.878 469.140 1.00 49.81  ? 123 LEU B CB  1 
ATOM 4268 C CG  . LEU D 4 123 ? 356.703 366.803 468.457 1.00 49.81  ? 123 LEU B CG  1 
ATOM 4269 C CD1 . LEU D 4 123 ? 356.664 366.977 466.972 1.00 49.81  ? 123 LEU B CD1 1 
ATOM 4270 C CD2 . LEU D 4 123 ? 358.117 366.872 468.936 1.00 49.81  ? 123 LEU B CD2 1 
ATOM 4271 N N   . VAL D 4 124 ? 353.343 365.725 468.155 1.00 52.30  ? 124 VAL B N   1 
ATOM 4272 C CA  . VAL D 4 124 ? 352.814 364.372 468.238 1.00 52.30  ? 124 VAL B CA  1 
ATOM 4273 C C   . VAL D 4 124 ? 353.760 363.469 467.473 1.00 52.30  ? 124 VAL B C   1 
ATOM 4274 O O   . VAL D 4 124 ? 353.723 363.431 466.242 1.00 52.30  ? 124 VAL B O   1 
ATOM 4275 C CB  . VAL D 4 124 ? 351.400 364.292 467.665 1.00 52.30  ? 124 VAL B CB  1 
ATOM 4276 C CG1 . VAL D 4 124 ? 350.837 362.923 467.871 1.00 52.30  ? 124 VAL B CG1 1 
ATOM 4277 C CG2 . VAL D 4 124 ? 350.530 365.322 468.315 1.00 52.30  ? 124 VAL B CG2 1 
ATOM 4278 N N   . VAL D 4 125 ? 354.608 362.737 468.182 1.00 52.46  ? 125 VAL B N   1 
ATOM 4279 C CA  . VAL D 4 125 ? 355.686 362.001 467.543 1.00 52.46  ? 125 VAL B CA  1 
ATOM 4280 C C   . VAL D 4 125 ? 355.565 360.527 467.917 1.00 52.46  ? 125 VAL B C   1 
ATOM 4281 O O   . VAL D 4 125 ? 355.122 360.171 469.009 1.00 52.46  ? 125 VAL B O   1 
ATOM 4282 C CB  . VAL D 4 125 ? 357.062 362.604 467.915 1.00 52.46  ? 125 VAL B CB  1 
ATOM 4283 C CG1 . VAL D 4 125 ? 357.387 362.420 469.364 1.00 52.46  ? 125 VAL B CG1 1 
ATOM 4284 C CG2 . VAL D 4 125 ? 358.153 362.067 467.059 1.00 52.46  ? 125 VAL B CG2 1 
ATOM 4285 N N   . CYS D 4 126 ? 355.901 359.661 466.961 1.00 57.80  ? 126 CYS B N   1 
ATOM 4286 C CA  . CYS D 4 126 ? 355.715 358.218 467.096 1.00 57.80  ? 126 CYS B CA  1 
ATOM 4287 C C   . CYS D 4 126 ? 357.072 357.532 466.993 1.00 57.80  ? 126 CYS B C   1 
ATOM 4288 O O   . CYS D 4 126 ? 357.622 357.396 465.900 1.00 57.80  ? 126 CYS B O   1 
ATOM 4289 C CB  . CYS D 4 126 ? 354.758 357.705 466.039 1.00 57.80  ? 126 CYS B CB  1 
ATOM 4290 S SG  . CYS D 4 126 ? 353.995 356.156 466.465 1.00 57.80  ? 126 CYS B SG  1 
ATOM 4291 N N   . VAL D 4 127 ? 357.591 357.076 468.124 1.00 56.09  ? 127 VAL B N   1 
ATOM 4292 C CA  . VAL D 4 127 ? 358.982 356.630 468.213 1.00 56.09  ? 127 VAL B CA  1 
ATOM 4293 C C   . VAL D 4 127 ? 359.022 355.106 468.171 1.00 56.09  ? 127 VAL B C   1 
ATOM 4294 O O   . VAL D 4 127 ? 358.349 354.461 468.980 1.00 56.09  ? 127 VAL B O   1 
ATOM 4295 C CB  . VAL D 4 127 ? 359.619 357.149 469.492 1.00 56.09  ? 127 VAL B CB  1 
ATOM 4296 C CG1 . VAL D 4 127 ? 361.033 356.692 469.579 1.00 56.09  ? 127 VAL B CG1 1 
ATOM 4297 C CG2 . VAL D 4 127 ? 359.552 358.646 469.542 1.00 56.09  ? 127 VAL B CG2 1 
ATOM 4298 N N   . PRO D 4 128 ? 359.773 354.502 467.261 1.00 57.15  ? 128 PRO B N   1 
ATOM 4299 C CA  . PRO D 4 128 ? 360.027 353.062 467.359 1.00 57.15  ? 128 PRO B CA  1 
ATOM 4300 C C   . PRO D 4 128 ? 361.213 352.717 468.241 1.00 57.15  ? 128 PRO B C   1 
ATOM 4301 O O   . PRO D 4 128 ? 362.254 353.367 468.152 1.00 57.15  ? 128 PRO B O   1 
ATOM 4302 C CB  . PRO D 4 128 ? 360.290 352.660 465.907 1.00 57.15  ? 128 PRO B CB  1 
ATOM 4303 C CG  . PRO D 4 128 ? 360.750 353.872 465.260 1.00 57.15  ? 128 PRO B CG  1 
ATOM 4304 C CD  . PRO D 4 128 ? 360.046 355.008 465.911 1.00 57.15  ? 128 PRO B CD  1 
ATOM 4305 N N   . GLU D 4 129 ? 361.049 351.689 469.080 1.00 61.85  ? 129 GLU B N   1 
ATOM 4306 C CA  . GLU D 4 129 ? 362.073 351.130 469.970 1.00 61.85  ? 129 GLU B CA  1 
ATOM 4307 C C   . GLU D 4 129 ? 362.624 352.190 470.925 1.00 61.85  ? 129 GLU B C   1 
ATOM 4308 O O   . GLU D 4 129 ? 363.816 352.475 470.971 1.00 61.85  ? 129 GLU B O   1 
ATOM 4309 C CB  . GLU D 4 129 ? 363.212 350.475 469.185 1.00 61.85  ? 129 GLU B CB  1 
ATOM 4310 C CG  . GLU D 4 129 ? 362.777 349.519 468.109 1.00 61.85  ? 129 GLU B CG  1 
ATOM 4311 C CD  . GLU D 4 129 ? 362.792 348.085 468.566 1.00 61.85  ? 129 GLU B CD  1 
ATOM 4312 O OE1 . GLU D 4 129 ? 362.710 347.850 469.785 1.00 61.85  ? 129 GLU B OE1 1 
ATOM 4313 O OE2 . GLU D 4 129 ? 362.903 347.188 467.708 1.00 61.85  ? 129 GLU B OE2 1 
ATOM 4314 N N   . ALA D 4 130 ? 361.715 352.765 471.697 1.00 61.76  ? 130 ALA B N   1 
ATOM 4315 C CA  . ALA D 4 130 ? 362.078 353.817 472.638 1.00 61.76  ? 130 ALA B CA  1 
ATOM 4316 C C   . ALA D 4 130 ? 362.453 353.175 473.962 1.00 61.76  ? 130 ALA B C   1 
ATOM 4317 O O   . ALA D 4 130 ? 361.601 352.904 474.803 1.00 61.76  ? 130 ALA B O   1 
ATOM 4318 C CB  . ALA D 4 130 ? 360.933 354.801 472.804 1.00 61.76  ? 130 ALA B CB  1 
ATOM 4319 N N   . GLU D 4 131 ? 363.743 352.921 474.156 1.00 65.27  ? 131 GLU B N   1 
ATOM 4320 C CA  . GLU D 4 131 ? 364.225 352.503 475.465 1.00 65.27  ? 131 GLU B CA  1 
ATOM 4321 C C   . GLU D 4 131 ? 364.169 353.683 476.418 1.00 65.27  ? 131 GLU B C   1 
ATOM 4322 O O   . GLU D 4 131 ? 364.696 354.754 476.117 1.00 65.27  ? 131 GLU B O   1 
ATOM 4323 C CB  . GLU D 4 131 ? 365.651 351.973 475.398 1.00 65.27  ? 131 GLU B CB  1 
ATOM 4324 C CG  . GLU D 4 131 ? 365.795 350.555 474.937 1.00 65.27  ? 131 GLU B CG  1 
ATOM 4325 C CD  . GLU D 4 131 ? 367.170 350.001 475.243 1.00 65.27  ? 131 GLU B CD  1 
ATOM 4326 O OE1 . GLU D 4 131 ? 367.996 350.740 475.808 1.00 65.27  ? 131 GLU B OE1 1 
ATOM 4327 O OE2 . GLU D 4 131 ? 367.437 348.831 474.918 1.00 65.27  ? 131 GLU B OE2 1 
ATOM 4328 N N   . MET D 4 132 ? 363.540 353.492 477.560 1.00 66.29  ? 132 MET B N   1 
ATOM 4329 C CA  . MET D 4 132 ? 363.530 354.504 478.595 1.00 66.29  ? 132 MET B CA  1 
ATOM 4330 C C   . MET D 4 132 ? 364.726 354.304 479.510 1.00 66.29  ? 132 MET B C   1 
ATOM 4331 O O   . MET D 4 132 ? 365.375 353.262 479.498 1.00 66.29  ? 132 MET B O   1 
ATOM 4332 C CB  . MET D 4 132 ? 362.229 354.441 479.387 1.00 66.29  ? 132 MET B CB  1 
ATOM 4333 C CG  . MET D 4 132 ? 360.997 354.814 478.577 1.00 66.29  ? 132 MET B CG  1 
ATOM 4334 S SD  . MET D 4 132 ? 360.850 356.580 478.308 1.00 66.29  ? 132 MET B SD  1 
ATOM 4335 C CE  . MET D 4 132 ? 359.731 356.604 476.932 1.00 66.29  ? 132 MET B CE  1 
ATOM 4336 N N   . GLY D 4 133 ? 365.019 355.318 480.301 1.00 64.54  ? 133 GLY B N   1 
ATOM 4337 C CA  . GLY D 4 133 ? 366.152 355.287 481.211 1.00 64.54  ? 133 GLY B CA  1 
ATOM 4338 C C   . GLY D 4 133 ? 365.686 355.315 482.651 1.00 64.54  ? 133 GLY B C   1 
ATOM 4339 O O   . GLY D 4 133 ? 364.779 356.066 482.998 1.00 64.54  ? 133 GLY B O   1 
ATOM 4340 N N   . CYS D 4 134 ? 366.307 354.491 483.480 1.00 67.75  ? 134 CYS B N   1 
ATOM 4341 C CA  . CYS D 4 134 ? 365.926 354.441 484.876 1.00 67.75  ? 134 CYS B CA  1 
ATOM 4342 C C   . CYS D 4 134 ? 366.521 355.618 485.630 1.00 67.75  ? 134 CYS B C   1 
ATOM 4343 O O   . CYS D 4 134 ? 367.459 356.271 485.173 1.00 67.75  ? 134 CYS B O   1 
ATOM 4344 C CB  . CYS D 4 134 ? 366.384 353.139 485.512 1.00 67.75  ? 134 CYS B CB  1 
ATOM 4345 S SG  . CYS D 4 134 ? 365.717 352.863 487.143 1.00 67.75  ? 134 CYS B SG  1 
ATOM 4346 N N   . SER D 4 135 ? 365.955 355.892 486.801 1.00 68.34  ? 135 SER B N   1 
ATOM 4347 C CA  . SER D 4 135 ? 366.446 356.999 487.608 1.00 68.34  ? 135 SER B CA  1 
ATOM 4348 C C   . SER D 4 135 ? 367.707 356.606 488.360 1.00 68.34  ? 135 SER B C   1 
ATOM 4349 O O   . SER D 4 135 ? 368.649 357.395 488.463 1.00 68.34  ? 135 SER B O   1 
ATOM 4350 C CB  . SER D 4 135 ? 365.367 357.458 488.576 1.00 68.34  ? 135 SER B CB  1 
ATOM 4351 O OG  . SER D 4 135 ? 364.913 356.381 489.363 1.00 68.34  ? 135 SER B OG  1 
ATOM 4352 N N   . ASN D 4 136 ? 367.734 355.399 488.909 1.00 70.38  ? 136 ASN B N   1 
ATOM 4353 C CA  . ASN D 4 136 ? 368.969 354.864 489.453 1.00 70.38  ? 136 ASN B CA  1 
ATOM 4354 C C   . ASN D 4 136 ? 369.866 354.441 488.305 1.00 70.38  ? 136 ASN B C   1 
ATOM 4355 O O   . ASN D 4 136 ? 369.397 353.901 487.305 1.00 70.38  ? 136 ASN B O   1 
ATOM 4356 C CB  . ASN D 4 136 ? 368.675 353.685 490.370 1.00 70.38  ? 136 ASN B CB  1 
ATOM 4357 C CG  . ASN D 4 136 ? 369.851 353.310 491.227 1.00 70.38  ? 136 ASN B CG  1 
ATOM 4358 O OD1 . ASN D 4 136 ? 370.886 353.966 491.203 1.00 70.38  ? 136 ASN B OD1 1 
ATOM 4359 N ND2 . ASN D 4 136 ? 369.693 352.260 492.011 1.00 70.38  ? 136 ASN B ND2 1 
ATOM 4360 N N   . LEU D 4 137 ? 371.159 354.700 488.438 1.00 67.49  ? 137 LEU B N   1 
ATOM 4361 C CA  . LEU D 4 137 ? 372.049 354.500 487.306 1.00 67.49  ? 137 LEU B CA  1 
ATOM 4362 C C   . LEU D 4 137 ? 372.476 353.056 487.133 1.00 67.49  ? 137 LEU B C   1 
ATOM 4363 O O   . LEU D 4 137 ? 373.114 352.741 486.126 1.00 67.49  ? 137 LEU B O   1 
ATOM 4364 C CB  . LEU D 4 137 ? 373.297 355.371 487.430 1.00 67.49  ? 137 LEU B CB  1 
ATOM 4365 C CG  . LEU D 4 137 ? 373.269 356.828 486.966 1.00 67.49  ? 137 LEU B CG  1 
ATOM 4366 C CD1 . LEU D 4 137 ? 372.823 356.896 485.539 1.00 67.49  ? 137 LEU B CD1 1 
ATOM 4367 C CD2 . LEU D 4 137 ? 372.430 357.734 487.840 1.00 67.49  ? 137 LEU B CD2 1 
ATOM 4368 N N   . ASN D 4 138 ? 372.158 352.176 488.079 1.00 70.44  ? 138 ASN B N   1 
ATOM 4369 C CA  . ASN D 4 138 ? 372.506 350.771 487.959 1.00 70.44  ? 138 ASN B CA  1 
ATOM 4370 C C   . ASN D 4 138 ? 371.356 349.894 487.504 1.00 70.44  ? 138 ASN B C   1 
ATOM 4371 O O   . ASN D 4 138 ? 371.592 348.937 486.764 1.00 70.44  ? 138 ASN B O   1 
ATOM 4372 C CB  . ASN D 4 138 ? 373.023 350.227 489.296 1.00 70.44  ? 138 ASN B CB  1 
ATOM 4373 C CG  . ASN D 4 138 ? 374.270 350.928 489.765 1.00 70.44  ? 138 ASN B CG  1 
ATOM 4374 O OD1 . ASN D 4 138 ? 375.379 350.549 489.404 1.00 70.44  ? 138 ASN B OD1 1 
ATOM 4375 N ND2 . ASN D 4 138 ? 374.099 351.955 490.580 1.00 70.44  ? 138 ASN B ND2 1 
ATOM 4376 N N   . ASN D 4 139 ? 370.133 350.196 487.909 1.00 70.84  ? 139 ASN B N   1 
ATOM 4377 C CA  . ASN D 4 139 ? 368.997 349.325 487.684 1.00 70.84  ? 139 ASN B CA  1 
ATOM 4378 C C   . ASN D 4 139 ? 368.332 349.636 486.351 1.00 70.84  ? 139 ASN B C   1 
ATOM 4379 O O   . ASN D 4 139 ? 368.854 350.375 485.518 1.00 70.84  ? 139 ASN B O   1 
ATOM 4380 C CB  . ASN D 4 139 ? 368.001 349.464 488.828 1.00 70.84  ? 139 ASN B CB  1 
ATOM 4381 C CG  . ASN D 4 139 ? 368.622 349.170 490.156 1.00 70.84  ? 139 ASN B CG  1 
ATOM 4382 O OD1 . ASN D 4 139 ? 369.576 348.405 490.244 1.00 70.84  ? 139 ASN B OD1 1 
ATOM 4383 N ND2 . ASN D 4 139 ? 368.086 349.769 491.207 1.00 70.84  ? 139 ASN B ND2 1 
ATOM 4384 N N   . THR D 4 140 ? 367.162 349.036 486.146 1.00 68.78  ? 140 THR B N   1 
ATOM 4385 C CA  . THR D 4 140 ? 366.296 349.159 484.990 1.00 68.78  ? 140 THR B CA  1 
ATOM 4386 C C   . THR D 4 140 ? 364.849 349.299 485.447 1.00 68.78  ? 140 THR B C   1 
ATOM 4387 O O   . THR D 4 140 ? 364.486 348.732 486.479 1.00 68.78  ? 140 THR B O   1 
ATOM 4388 C CB  . THR D 4 140 ? 366.434 347.934 484.076 1.00 68.78  ? 140 THR B CB  1 
ATOM 4389 O OG1 . THR D 4 140 ? 366.232 346.745 484.843 1.00 68.78  ? 140 THR B OG1 1 
ATOM 4390 C CG2 . THR D 4 140 ? 367.794 347.891 483.405 1.00 68.78  ? 140 THR B CG2 1 
ATOM 4391 N N   . PRO D 4 141 ? 364.009 350.044 484.725 1.00 69.48  ? 141 PRO B N   1 
ATOM 4392 C CA  . PRO D 4 141 ? 362.650 350.303 485.211 1.00 69.48  ? 141 PRO B CA  1 
ATOM 4393 C C   . PRO D 4 141 ? 361.756 349.075 485.171 1.00 69.48  ? 141 PRO B C   1 
ATOM 4394 O O   . PRO D 4 141 ? 362.085 348.054 484.568 1.00 69.48  ? 141 PRO B O   1 
ATOM 4395 C CB  . PRO D 4 141 ? 362.139 351.379 484.252 1.00 69.48  ? 141 PRO B CB  1 
ATOM 4396 C CG  . PRO D 4 141 ? 362.937 351.207 483.047 1.00 69.48  ? 141 PRO B CG  1 
ATOM 4397 C CD  . PRO D 4 141 ? 364.286 350.819 483.506 1.00 69.48  ? 141 PRO B CD  1 
ATOM 4398 N N   . GLU D 4 142 ? 360.616 349.180 485.845 1.00 73.50  ? 142 GLU B N   1 
ATOM 4399 C CA  . GLU D 4 142 ? 359.700 348.059 485.950 1.00 73.50  ? 142 GLU B CA  1 
ATOM 4400 C C   . GLU D 4 142 ? 358.525 348.230 484.996 1.00 73.50  ? 142 GLU B C   1 
ATOM 4401 O O   . GLU D 4 142 ? 358.309 349.291 484.413 1.00 73.50  ? 142 GLU B O   1 
ATOM 4402 C CB  . GLU D 4 142 ? 359.211 347.910 487.382 1.00 73.50  ? 142 GLU B CB  1 
ATOM 4403 C CG  . GLU D 4 142 ? 358.731 349.193 487.980 1.00 73.50  ? 142 GLU B CG  1 
ATOM 4404 C CD  . GLU D 4 142 ? 358.315 349.029 489.415 1.00 73.50  ? 142 GLU B CD  1 
ATOM 4405 O OE1 . GLU D 4 142 ? 358.273 350.042 490.138 1.00 73.50  ? 142 GLU B OE1 1 
ATOM 4406 O OE2 . GLU D 4 142 ? 358.030 347.888 489.823 1.00 73.50  ? 142 GLU B OE2 1 
ATOM 4407 N N   . PHE D 4 143 ? 357.740 347.164 484.853 1.00 71.12  ? 143 PHE B N   1 
ATOM 4408 C CA  . PHE D 4 143 ? 356.688 347.128 483.847 1.00 71.12  ? 143 PHE B CA  1 
ATOM 4409 C C   . PHE D 4 143 ? 355.495 347.975 484.256 1.00 71.12  ? 143 PHE B C   1 
ATOM 4410 O O   . PHE D 4 143 ? 354.783 348.501 483.400 1.00 71.12  ? 143 PHE B O   1 
ATOM 4411 C CB  . PHE D 4 143 ? 356.270 345.682 483.602 1.00 71.12  ? 143 PHE B CB  1 
ATOM 4412 C CG  . PHE D 4 143 ? 355.160 345.526 482.615 1.00 71.12  ? 143 PHE B CG  1 
ATOM 4413 C CD1 . PHE D 4 143 ? 355.255 346.075 481.352 1.00 71.12  ? 143 PHE B CD1 1 
ATOM 4414 C CD2 . PHE D 4 143 ? 354.026 344.814 482.946 1.00 71.12  ? 143 PHE B CD2 1 
ATOM 4415 C CE1 . PHE D 4 143 ? 354.236 345.926 480.440 1.00 71.12  ? 143 PHE B CE1 1 
ATOM 4416 C CE2 . PHE D 4 143 ? 353.004 344.660 482.039 1.00 71.12  ? 143 PHE B CE2 1 
ATOM 4417 C CZ  . PHE D 4 143 ? 353.111 345.217 480.785 1.00 71.12  ? 143 PHE B CZ  1 
ATOM 4418 N N   . SER D 4 144 ? 355.267 348.127 485.557 1.00 71.61  ? 144 SER B N   1 
ATOM 4419 C CA  . SER D 4 144 ? 354.186 348.984 486.021 1.00 71.61  ? 144 SER B CA  1 
ATOM 4420 C C   . SER D 4 144 ? 354.504 350.453 485.831 1.00 71.61  ? 144 SER B C   1 
ATOM 4421 O O   . SER D 4 144 ? 353.586 351.273 485.763 1.00 71.61  ? 144 SER B O   1 
ATOM 4422 C CB  . SER D 4 144 ? 353.902 348.709 487.492 1.00 71.61  ? 144 SER B CB  1 
ATOM 4423 O OG  . SER D 4 144 ? 354.943 349.214 488.304 1.00 71.61  ? 144 SER B OG  1 
ATOM 4424 N N   . GLU D 4 145 ? 355.782 350.797 485.743 1.00 73.25  ? 145 GLU B N   1 
ATOM 4425 C CA  . GLU D 4 145 ? 356.225 352.171 485.604 1.00 73.25  ? 145 GLU B CA  1 
ATOM 4426 C C   . GLU D 4 145 ? 356.497 352.552 484.160 1.00 73.25  ? 145 GLU B C   1 
ATOM 4427 O O   . GLU D 4 145 ? 356.324 353.718 483.800 1.00 73.25  ? 145 GLU B O   1 
ATOM 4428 C CB  . GLU D 4 145 ? 357.483 352.381 486.450 1.00 73.25  ? 145 GLU B CB  1 
ATOM 4429 C CG  . GLU D 4 145 ? 357.997 353.788 486.519 1.00 73.25  ? 145 GLU B CG  1 
ATOM 4430 C CD  . GLU D 4 145 ? 357.089 354.703 487.297 1.00 73.25  ? 145 GLU B CD  1 
ATOM 4431 O OE1 . GLU D 4 145 ? 356.406 354.217 488.218 1.00 73.25  ? 145 GLU B OE1 1 
ATOM 4432 O OE2 . GLU D 4 145 ? 357.057 355.911 486.986 1.00 73.25  ? 145 GLU B OE2 1 
ATOM 4433 N N   . LEU D 4 146 ? 356.864 351.596 483.316 1.00 67.61  ? 146 LEU B N   1 
ATOM 4434 C CA  . LEU D 4 146 ? 357.136 351.906 481.922 1.00 67.61  ? 146 LEU B CA  1 
ATOM 4435 C C   . LEU D 4 146 ? 355.867 352.224 481.160 1.00 67.61  ? 146 LEU B C   1 
ATOM 4436 O O   . LEU D 4 146 ? 355.874 353.084 480.277 1.00 67.61  ? 146 LEU B O   1 
ATOM 4437 C CB  . LEU D 4 146 ? 357.838 350.740 481.244 1.00 67.61  ? 146 LEU B CB  1 
ATOM 4438 C CG  . LEU D 4 146 ? 359.344 350.671 481.358 1.00 67.61  ? 146 LEU B CG  1 
ATOM 4439 C CD1 . LEU D 4 146 ? 359.795 349.411 480.710 1.00 67.61  ? 146 LEU B CD1 1 
ATOM 4440 C CD2 . LEU D 4 146 ? 359.938 351.841 480.667 1.00 67.61  ? 146 LEU B CD2 1 
ATOM 4441 N N   . SER D 4 147 ? 354.775 351.541 481.472 1.00 72.11  ? 147 SER B N   1 
ATOM 4442 C CA  . SER D 4 147 ? 353.570 351.653 480.667 1.00 72.11  ? 147 SER B CA  1 
ATOM 4443 C C   . SER D 4 147 ? 352.347 351.361 481.512 1.00 72.11  ? 147 SER B C   1 
ATOM 4444 O O   . SER D 4 147 ? 352.177 350.238 481.989 1.00 72.11  ? 147 SER B O   1 
ATOM 4445 C CB  . SER D 4 147 ? 353.621 350.692 479.487 1.00 72.11  ? 147 SER B CB  1 
ATOM 4446 O OG  . SER D 4 147 ? 353.282 349.383 479.897 1.00 72.11  ? 147 SER B OG  1 
ATOM 4447 N N   . GLY D 4 148 ? 351.490 352.364 481.677 1.00 74.86  ? 148 GLY B N   1 
ATOM 4448 C CA  . GLY D 4 148 ? 350.155 352.110 482.175 1.00 74.86  ? 148 GLY B CA  1 
ATOM 4449 C C   . GLY D 4 148 ? 349.318 351.582 481.035 1.00 74.86  ? 148 GLY B C   1 
ATOM 4450 O O   . GLY D 4 148 ? 349.352 352.120 479.924 1.00 74.86  ? 148 GLY B O   1 
ATOM 4451 N N   . GLY D 4 149 ? 348.599 350.497 481.289 1.00 78.84  ? 149 GLY B N   1 
ATOM 4452 C CA  . GLY D 4 149 ? 347.755 349.920 480.271 1.00 78.84  ? 149 GLY B CA  1 
ATOM 4453 C C   . GLY D 4 149 ? 346.570 350.821 480.039 1.00 78.84  ? 149 GLY B C   1 
ATOM 4454 O O   . GLY D 4 149 ? 345.911 351.208 481.005 1.00 78.84  ? 149 GLY B O   1 
ATOM 4455 N N   . ASP D 4 150 ? 346.338 351.186 478.770 1.00 80.15  ? 150 ASP B N   1 
ATOM 4456 C CA  . ASP D 4 150 ? 345.342 352.130 478.242 1.00 80.15  ? 150 ASP B CA  1 
ATOM 4457 C C   . ASP D 4 150 ? 345.195 353.408 479.064 1.00 80.15  ? 150 ASP B C   1 
ATOM 4458 O O   . ASP D 4 150 ? 344.106 353.979 479.151 1.00 80.15  ? 150 ASP B O   1 
ATOM 4459 C CB  . ASP D 4 150 ? 343.974 351.434 478.037 1.00 80.15  ? 150 ASP B CB  1 
ATOM 4460 C CG  . ASP D 4 150 ? 343.370 350.810 479.314 1.00 80.15  ? 150 ASP B CG  1 
ATOM 4461 O OD1 . ASP D 4 150 ? 343.199 351.489 480.352 1.00 80.15  ? 150 ASP B OD1 1 
ATOM 4462 O OD2 . ASP D 4 150 ? 343.083 349.597 479.280 1.00 80.15  ? 150 ASP B OD2 1 
ATOM 4463 N N   . SER D 4 151 ? 346.302 353.882 479.624 1.00 71.04  ? 151 SER B N   1 
ATOM 4464 C CA  . SER D 4 151 ? 346.328 355.027 480.514 1.00 71.04  ? 151 SER B CA  1 
ATOM 4465 C C   . SER D 4 151 ? 347.652 355.736 480.311 1.00 71.04  ? 151 SER B C   1 
ATOM 4466 O O   . SER D 4 151 ? 348.695 355.093 480.206 1.00 71.04  ? 151 SER B O   1 
ATOM 4467 C CB  . SER D 4 151 ? 346.171 354.610 481.973 1.00 71.04  ? 151 SER B CB  1 
ATOM 4468 O OG  . SER D 4 151 ? 346.312 355.725 482.826 1.00 71.04  ? 151 SER B OG  1 
ATOM 4469 N N   . ALA D 4 152 ? 347.605 357.055 480.249 1.00 62.58  ? 152 ALA B N   1 
ATOM 4470 C CA  . ALA D 4 152 ? 348.772 357.826 479.864 1.00 62.58  ? 152 ALA B CA  1 
ATOM 4471 C C   . ALA D 4 152 ? 349.724 357.984 481.035 1.00 62.58  ? 152 ALA B C   1 
ATOM 4472 O O   . ALA D 4 152 ? 349.299 358.271 482.157 1.00 62.58  ? 152 ALA B O   1 
ATOM 4473 C CB  . ALA D 4 152 ? 348.345 359.192 479.347 1.00 62.58  ? 152 ALA B CB  1 
ATOM 4474 N N   . ARG D 4 153 ? 351.008 357.783 480.772 1.00 61.13  ? 153 ARG B N   1 
ATOM 4475 C CA  . ARG D 4 153 ? 352.046 358.122 481.723 1.00 61.13  ? 153 ARG B CA  1 
ATOM 4476 C C   . ARG D 4 153 ? 352.534 359.535 481.449 1.00 61.13  ? 153 ARG B C   1 
ATOM 4477 O O   . ARG D 4 153 ? 352.522 360.003 480.318 1.00 61.13  ? 153 ARG B O   1 
ATOM 4478 C CB  . ARG D 4 153 ? 353.199 357.136 481.620 1.00 61.13  ? 153 ARG B CB  1 
ATOM 4479 C CG  . ARG D 4 153 ? 352.918 355.797 482.217 1.00 61.13  ? 153 ARG B CG  1 
ATOM 4480 C CD  . ARG D 4 153 ? 353.069 355.859 483.707 1.00 61.13  ? 153 ARG B CD  1 
ATOM 4481 N NE  . ARG D 4 153 ? 352.773 354.581 484.338 1.00 61.13  ? 153 ARG B NE  1 
ATOM 4482 C CZ  . ARG D 4 153 ? 351.552 354.166 484.658 1.00 61.13  ? 153 ARG B CZ  1 
ATOM 4483 N NH1 . ARG D 4 153 ? 351.386 352.985 485.231 1.00 61.13  ? 153 ARG B NH1 1 
ATOM 4484 N NH2 . ARG D 4 153 ? 350.493 354.919 484.401 1.00 61.13  ? 153 ARG B NH2 1 
ATOM 4485 N N   . MET D 4 154 ? 352.974 360.220 482.491 1.00 57.36  ? 154 MET B N   1 
ATOM 4486 C CA  . MET D 4 154 ? 353.297 361.632 482.384 1.00 57.36  ? 154 MET B CA  1 
ATOM 4487 C C   . MET D 4 154 ? 354.795 361.860 482.442 1.00 57.36  ? 154 MET B C   1 
ATOM 4488 O O   . MET D 4 154 ? 355.487 361.270 483.273 1.00 57.36  ? 154 MET B O   1 
ATOM 4489 C CB  . MET D 4 154 ? 352.654 362.429 483.506 1.00 57.36  ? 154 MET B CB  1 
ATOM 4490 C CG  . MET D 4 154 ? 351.161 362.410 483.520 1.00 57.36  ? 154 MET B CG  1 
ATOM 4491 S SD  . MET D 4 154 ? 350.559 363.465 484.833 1.00 57.36  ? 154 MET B SD  1 
ATOM 4492 C CE  . MET D 4 154 ? 348.825 363.069 484.775 1.00 57.36  ? 154 MET B CE  1 
ATOM 4493 N N   . PHE D 4 155 ? 355.287 362.746 481.583 1.00 55.56  ? 155 PHE B N   1 
ATOM 4494 C CA  . PHE D 4 155 ? 356.585 363.351 481.806 1.00 55.56  ? 155 PHE B CA  1 
ATOM 4495 C C   . PHE D 4 155 ? 356.492 364.338 482.959 1.00 55.56  ? 155 PHE B C   1 
ATOM 4496 O O   . PHE D 4 155 ? 355.410 364.710 483.407 1.00 55.56  ? 155 PHE B O   1 
ATOM 4497 C CB  . PHE D 4 155 ? 357.067 364.084 480.564 1.00 55.56  ? 155 PHE B CB  1 
ATOM 4498 C CG  . PHE D 4 155 ? 357.478 363.194 479.454 1.00 55.56  ? 155 PHE B CG  1 
ATOM 4499 C CD1 . PHE D 4 155 ? 358.617 362.428 479.549 1.00 55.56  ? 155 PHE B CD1 1 
ATOM 4500 C CD2 . PHE D 4 155 ? 356.744 363.135 478.292 1.00 55.56  ? 155 PHE B CD2 1 
ATOM 4501 C CE1 . PHE D 4 155 ? 359.001 361.608 478.519 1.00 55.56  ? 155 PHE B CE1 1 
ATOM 4502 C CE2 . PHE D 4 155 ? 357.125 362.321 477.258 1.00 55.56  ? 155 PHE B CE2 1 
ATOM 4503 C CZ  . PHE D 4 155 ? 358.252 361.557 477.374 1.00 55.56  ? 155 PHE B CZ  1 
ATOM 4504 N N   . THR D 4 156 ? 357.642 364.777 483.443 1.00 61.36  ? 156 THR B N   1 
ATOM 4505 C CA  . THR D 4 156 ? 357.713 365.830 484.442 1.00 61.36  ? 156 THR B CA  1 
ATOM 4506 C C   . THR D 4 156 ? 358.682 366.900 483.971 1.00 61.36  ? 156 THR B C   1 
ATOM 4507 O O   . THR D 4 156 ? 359.494 366.684 483.074 1.00 61.36  ? 156 THR B O   1 
ATOM 4508 C CB  . THR D 4 156 ? 358.160 365.302 485.808 1.00 61.36  ? 156 THR B CB  1 
ATOM 4509 O OG1 . THR D 4 156 ? 359.423 364.648 485.671 1.00 61.36  ? 156 THR B OG1 1 
ATOM 4510 C CG2 . THR D 4 156 ? 357.152 364.339 486.386 1.00 61.36  ? 156 THR B CG2 1 
ATOM 4511 N N   . ASP D 4 157 ? 358.583 368.072 484.579 1.00 64.16  ? 157 ASP B N   1 
ATOM 4512 C CA  . ASP D 4 157 ? 359.527 369.144 484.324 1.00 64.16  ? 157 ASP B CA  1 
ATOM 4513 C C   . ASP D 4 157 ? 360.479 369.374 485.479 1.00 64.16  ? 157 ASP B C   1 
ATOM 4514 O O   . ASP D 4 157 ? 361.063 370.452 485.578 1.00 64.16  ? 157 ASP B O   1 
ATOM 4515 C CB  . ASP D 4 157 ? 358.784 370.426 483.985 1.00 64.16  ? 157 ASP B CB  1 
ATOM 4516 C CG  . ASP D 4 157 ? 357.719 370.747 484.979 1.00 64.16  ? 157 ASP B CG  1 
ATOM 4517 O OD1 . ASP D 4 157 ? 357.496 369.932 485.888 1.00 64.16  ? 157 ASP B OD1 1 
ATOM 4518 O OD2 . ASP D 4 157 ? 357.085 371.810 484.842 1.00 64.16  ? 157 ASP B OD2 1 
ATOM 4519 N N   . THR D 4 158 ? 360.612 368.404 486.368 1.00 66.01  ? 158 THR B N   1 
ATOM 4520 C CA  . THR D 4 158 ? 361.650 368.349 487.376 1.00 66.01  ? 158 THR B CA  1 
ATOM 4521 C C   . THR D 4 158 ? 362.395 367.038 487.206 1.00 66.01  ? 158 THR B C   1 
ATOM 4522 O O   . THR D 4 158 ? 362.064 366.222 486.350 1.00 66.01  ? 158 THR B O   1 
ATOM 4523 C CB  . THR D 4 158 ? 361.070 368.451 488.785 1.00 66.01  ? 158 THR B CB  1 
ATOM 4524 O OG1 . THR D 4 158 ? 360.056 367.459 488.950 1.00 66.01  ? 158 THR B OG1 1 
ATOM 4525 C CG2 . THR D 4 158 ? 360.459 369.793 488.996 1.00 66.01  ? 158 THR B CG2 1 
ATOM 4526 N N   . GLN D 4 159 ? 363.416 366.834 488.019 1.00 65.51  ? 159 GLN B N   1 
ATOM 4527 C CA  . GLN D 4 159 ? 364.138 365.583 487.922 1.00 65.51  ? 159 GLN B CA  1 
ATOM 4528 C C   . GLN D 4 159 ? 363.566 364.551 488.881 1.00 65.51  ? 159 GLN B C   1 
ATOM 4529 O O   . GLN D 4 159 ? 363.154 364.861 489.999 1.00 65.51  ? 159 GLN B O   1 
ATOM 4530 C CB  . GLN D 4 159 ? 365.608 365.790 488.228 1.00 65.51  ? 159 GLN B CB  1 
ATOM 4531 C CG  . GLN D 4 159 ? 366.337 366.541 487.184 1.00 65.51  ? 159 GLN B CG  1 
ATOM 4532 C CD  . GLN D 4 159 ? 367.813 366.338 487.291 1.00 65.51  ? 159 GLN B CD  1 
ATOM 4533 O OE1 . GLN D 4 159 ? 368.586 367.000 486.613 1.00 65.51  ? 159 GLN B OE1 1 
ATOM 4534 N NE2 . GLN D 4 159 ? 368.223 365.417 488.148 1.00 65.51  ? 159 GLN B NE2 1 
ATOM 4535 N N   . VAL D 4 160 ? 363.553 363.307 488.433 1.00 64.93  ? 160 VAL B N   1 
ATOM 4536 C CA  . VAL D 4 160 ? 363.258 362.172 489.292 1.00 64.93  ? 160 VAL B CA  1 
ATOM 4537 C C   . VAL D 4 160 ? 364.546 361.807 490.001 1.00 64.93  ? 160 VAL B C   1 
ATOM 4538 O O   . VAL D 4 160 ? 365.604 361.724 489.372 1.00 64.93  ? 160 VAL B O   1 
ATOM 4539 C CB  . VAL D 4 160 ? 362.707 360.987 488.484 1.00 64.93  ? 160 VAL B CB  1 
ATOM 4540 C CG1 . VAL D 4 160 ? 362.201 359.923 489.401 1.00 64.93  ? 160 VAL B CG1 1 
ATOM 4541 C CG2 . VAL D 4 160 ? 361.603 361.448 487.582 1.00 64.93  ? 160 VAL B CG2 1 
ATOM 4542 N N   . GLY D 4 161 ? 364.467 361.613 491.312 1.00 70.57  ? 161 GLY B N   1 
ATOM 4543 C CA  . GLY D 4 161 ? 365.666 361.458 492.104 1.00 70.57  ? 161 GLY B CA  1 
ATOM 4544 C C   . GLY D 4 161 ? 366.331 360.117 491.900 1.00 70.57  ? 161 GLY B C   1 
ATOM 4545 O O   . GLY D 4 161 ? 365.783 359.208 491.294 1.00 70.57  ? 161 GLY B O   1 
ATOM 4546 N N   . GLU D 4 162 ? 367.552 360.004 492.405 1.00 76.63  ? 162 GLU B N   1 
ATOM 4547 C CA  . GLU D 4 162 ? 368.301 358.763 492.277 1.00 76.63  ? 162 GLU B CA  1 
ATOM 4548 C C   . GLU D 4 162 ? 367.996 357.778 493.389 1.00 76.63  ? 162 GLU B C   1 
ATOM 4549 O O   . GLU D 4 162 ? 368.430 356.626 493.319 1.00 76.63  ? 162 GLU B O   1 
ATOM 4550 C CB  . GLU D 4 162 ? 369.799 359.048 492.283 1.00 76.63  ? 162 GLU B CB  1 
ATOM 4551 C CG  . GLU D 4 162 ? 370.304 359.832 491.098 1.00 76.63  ? 162 GLU B CG  1 
ATOM 4552 C CD  . GLU D 4 162 ? 371.779 360.148 491.218 1.00 76.63  ? 162 GLU B CD  1 
ATOM 4553 O OE1 . GLU D 4 162 ? 372.360 359.874 492.289 1.00 76.63  ? 162 GLU B OE1 1 
ATOM 4554 O OE2 . GLU D 4 162 ? 372.358 360.668 490.244 1.00 76.63  ? 162 GLU B OE2 1 
ATOM 4555 N N   . SER D 4 163 ? 367.270 358.210 494.417 1.00 80.16  ? 163 SER B N   1 
ATOM 4556 C CA  . SER D 4 163 ? 367.095 357.385 495.600 1.00 80.16  ? 163 SER B CA  1 
ATOM 4557 C C   . SER D 4 163 ? 366.117 356.248 495.377 1.00 80.16  ? 163 SER B C   1 
ATOM 4558 O O   . SER D 4 163 ? 366.310 355.167 495.939 1.00 80.16  ? 163 SER B O   1 
ATOM 4559 C CB  . SER D 4 163 ? 366.619 358.238 496.769 1.00 80.16  ? 163 SER B CB  1 
ATOM 4560 O OG  . SER D 4 163 ? 365.307 358.716 496.540 1.00 80.16  ? 163 SER B OG  1 
ATOM 4561 N N   . ASN D 4 164 ? 365.072 356.462 494.591 1.00 78.18  ? 164 ASN B N   1 
ATOM 4562 C CA  . ASN D 4 164 ? 364.115 355.399 494.348 1.00 78.18  ? 164 ASN B CA  1 
ATOM 4563 C C   . ASN D 4 164 ? 364.634 354.465 493.267 1.00 78.18  ? 164 ASN B C   1 
ATOM 4564 O O   . ASN D 4 164 ? 365.335 354.876 492.342 1.00 78.18  ? 164 ASN B O   1 
ATOM 4565 C CB  . ASN D 4 164 ? 362.755 355.981 493.978 1.00 78.18  ? 164 ASN B CB  1 
ATOM 4566 C CG  . ASN D 4 164 ? 362.876 357.192 493.114 1.00 78.18  ? 164 ASN B CG  1 
ATOM 4567 O OD1 . ASN D 4 164 ? 363.936 357.462 492.575 1.00 78.18  ? 164 ASN B OD1 1 
ATOM 4568 N ND2 . ASN D 4 164 ? 361.804 357.961 493.011 1.00 78.18  ? 164 ASN B ND2 1 
ATOM 4569 N N   . ALA D 4 165 ? 364.279 353.189 493.398 1.00 75.71  ? 165 ALA B N   1 
ATOM 4570 C CA  . ALA D 4 165 ? 365.025 352.143 492.715 1.00 75.71  ? 165 ALA B CA  1 
ATOM 4571 C C   . ALA D 4 165 ? 364.633 352.031 491.250 1.00 75.71  ? 165 ALA B C   1 
ATOM 4572 O O   . ALA D 4 165 ? 365.464 352.224 490.360 1.00 75.71  ? 165 ALA B O   1 
ATOM 4573 C CB  . ALA D 4 165 ? 364.820 350.812 493.434 1.00 75.71  ? 165 ALA B CB  1 
ATOM 4574 N N   . LYS D 4 166 ? 363.374 351.717 490.972 1.00 74.73  ? 166 LYS B N   1 
ATOM 4575 C CA  . LYS D 4 166 ? 363.019 351.355 489.600 1.00 74.73  ? 166 LYS B CA  1 
ATOM 4576 C C   . LYS D 4 166 ? 361.914 352.296 489.124 1.00 74.73  ? 166 LYS B C   1 
ATOM 4577 O O   . LYS D 4 166 ? 360.732 351.960 489.178 1.00 74.73  ? 166 LYS B O   1 
ATOM 4578 C CB  . LYS D 4 166 ? 362.595 349.898 489.519 1.00 74.73  ? 166 LYS B CB  1 
ATOM 4579 C CG  . LYS D 4 166 ? 363.725 348.930 489.826 1.00 74.73  ? 166 LYS B CG  1 
ATOM 4580 C CD  . LYS D 4 166 ? 363.235 347.512 489.997 1.00 74.73  ? 166 LYS B CD  1 
ATOM 4581 C CE  . LYS D 4 166 ? 362.832 346.906 488.672 1.00 74.73  ? 166 LYS B CE  1 
ATOM 4582 N NZ  . LYS D 4 166 ? 362.347 345.511 488.823 1.00 74.73  ? 166 LYS B NZ  1 
ATOM 4583 N N   . LYS D 4 167 ? 362.322 353.464 488.636 1.00 70.30  ? 167 LYS B N   1 
ATOM 4584 C CA  . LYS D 4 167 ? 361.409 354.460 488.104 1.00 70.30  ? 167 LYS B CA  1 
ATOM 4585 C C   . LYS D 4 167 ? 362.042 355.082 486.876 1.00 70.30  ? 167 LYS B C   1 
ATOM 4586 O O   . LYS D 4 167 ? 363.263 355.181 486.771 1.00 70.30  ? 167 LYS B O   1 
ATOM 4587 C CB  . LYS D 4 167 ? 361.092 355.554 489.122 1.00 70.30  ? 167 LYS B CB  1 
ATOM 4588 C CG  . LYS D 4 167 ? 360.150 355.128 490.215 1.00 70.30  ? 167 LYS B CG  1 
ATOM 4589 C CD  . LYS D 4 167 ? 359.648 356.312 490.994 1.00 70.30  ? 167 LYS B CD  1 
ATOM 4590 C CE  . LYS D 4 167 ? 358.786 357.195 490.131 1.00 70.30  ? 167 LYS B CE  1 
ATOM 4591 N NZ  . LYS D 4 167 ? 358.403 358.437 490.852 1.00 70.30  ? 167 LYS B NZ  1 
ATOM 4592 N N   . VAL D 4 168 ? 361.203 355.519 485.954 1.00 65.35  ? 168 VAL B N   1 
ATOM 4593 C CA  . VAL D 4 168 ? 361.681 356.067 484.693 1.00 65.35  ? 168 VAL B CA  1 
ATOM 4594 C C   . VAL D 4 168 ? 362.098 357.514 484.904 1.00 65.35  ? 168 VAL B C   1 
ATOM 4595 O O   . VAL D 4 168 ? 361.348 358.307 485.480 1.00 65.35  ? 168 VAL B O   1 
ATOM 4596 C CB  . VAL D 4 168 ? 360.595 355.953 483.619 1.00 65.35  ? 168 VAL B CB  1 
ATOM 4597 C CG1 . VAL D 4 168 ? 361.072 356.534 482.312 1.00 65.35  ? 168 VAL B CG1 1 
ATOM 4598 C CG2 . VAL D 4 168 ? 360.208 354.520 483.445 1.00 65.35  ? 168 VAL B CG2 1 
ATOM 4599 N N   . GLN D 4 169 ? 363.299 357.861 484.452 1.00 60.43  ? 169 GLN B N   1 
ATOM 4600 C CA  . GLN D 4 169 ? 363.753 359.244 484.516 1.00 60.43  ? 169 GLN B CA  1 
ATOM 4601 C C   . GLN D 4 169 ? 363.025 360.051 483.460 1.00 60.43  ? 169 GLN B C   1 
ATOM 4602 O O   . GLN D 4 169 ? 363.235 359.850 482.263 1.00 60.43  ? 169 GLN B O   1 
ATOM 4603 C CB  . GLN D 4 169 ? 365.254 359.330 484.300 1.00 60.43  ? 169 GLN B CB  1 
ATOM 4604 C CG  . GLN D 4 169 ? 365.753 360.739 484.209 1.00 60.43  ? 169 GLN B CG  1 
ATOM 4605 C CD  . GLN D 4 169 ? 365.827 361.395 485.551 1.00 60.43  ? 169 GLN B CD  1 
ATOM 4606 O OE1 . GLN D 4 169 ? 364.888 362.045 485.990 1.00 60.43  ? 169 GLN B OE1 1 
ATOM 4607 N NE2 . GLN D 4 169 ? 366.949 361.222 486.223 1.00 60.43  ? 169 GLN B NE2 1 
ATOM 4608 N N   . THR D 4 170 ? 362.183 360.979 483.897 1.00 60.36  ? 170 THR B N   1 
ATOM 4609 C CA  . THR D 4 170 ? 361.299 361.685 482.984 1.00 60.36  ? 170 THR B CA  1 
ATOM 4610 C C   . THR D 4 170 ? 361.572 363.179 482.955 1.00 60.36  ? 170 THR B C   1 
ATOM 4611 O O   . THR D 4 170 ? 360.643 363.979 483.078 1.00 60.36  ? 170 THR B O   1 
ATOM 4612 C CB  . THR D 4 170 ? 359.851 361.449 483.369 1.00 60.36  ? 170 THR B CB  1 
ATOM 4613 O OG1 . THR D 4 170 ? 359.671 361.829 484.732 1.00 60.36  ? 170 THR B OG1 1 
ATOM 4614 C CG2 . THR D 4 170 ? 359.490 360.011 483.208 1.00 60.36  ? 170 THR B CG2 1 
ATOM 4615 N N   . ALA D 4 171 ? 362.835 363.572 482.827 1.00 60.76  ? 171 ALA B N   1 
ATOM 4616 C CA  . ALA D 4 171 ? 363.167 364.958 482.534 1.00 60.76  ? 171 ALA B CA  1 
ATOM 4617 C C   . ALA D 4 171 ? 362.824 365.226 481.081 1.00 60.76  ? 171 ALA B C   1 
ATOM 4618 O O   . ALA D 4 171 ? 363.495 364.710 480.183 1.00 60.76  ? 171 ALA B O   1 
ATOM 4619 C CB  . ALA D 4 171 ? 364.641 365.227 482.801 1.00 60.76  ? 171 ALA B CB  1 
ATOM 4620 N N   . VAL D 4 172 ? 361.788 366.034 480.853 1.00 57.75  ? 172 VAL B N   1 
ATOM 4621 C CA  . VAL D 4 172 ? 361.138 366.096 479.550 1.00 57.75  ? 172 VAL B CA  1 
ATOM 4622 C C   . VAL D 4 172 ? 362.024 366.723 478.486 1.00 57.75  ? 172 VAL B C   1 
ATOM 4623 O O   . VAL D 4 172 ? 361.895 366.377 477.308 1.00 57.75  ? 172 VAL B O   1 
ATOM 4624 C CB  . VAL D 4 172 ? 359.796 366.834 479.692 1.00 57.75  ? 172 VAL B CB  1 
ATOM 4625 C CG1 . VAL D 4 172 ? 359.998 368.258 480.166 1.00 57.75  ? 172 VAL B CG1 1 
ATOM 4626 C CG2 . VAL D 4 172 ? 358.956 366.762 478.421 1.00 57.75  ? 172 VAL B CG2 1 
ATOM 4627 N N   . TRP D 4 173 ? 362.988 367.562 478.862 1.00 56.35  ? 173 TRP B N   1 
ATOM 4628 C CA  . TRP D 4 173 ? 363.899 368.102 477.865 1.00 56.35  ? 173 TRP B CA  1 
ATOM 4629 C C   . TRP D 4 173 ? 364.880 367.068 477.348 1.00 56.35  ? 173 TRP B C   1 
ATOM 4630 O O   . TRP D 4 173 ? 365.538 367.322 476.339 1.00 56.35  ? 173 TRP B O   1 
ATOM 4631 C CB  . TRP D 4 173 ? 364.666 369.293 478.419 1.00 56.35  ? 173 TRP B CB  1 
ATOM 4632 C CG  . TRP D 4 173 ? 365.483 368.986 479.592 1.00 56.35  ? 173 TRP B CG  1 
ATOM 4633 C CD1 . TRP D 4 173 ? 366.786 368.629 479.603 1.00 56.35  ? 173 TRP B CD1 1 
ATOM 4634 C CD2 . TRP D 4 173 ? 365.063 369.023 480.948 1.00 56.35  ? 173 TRP B CD2 1 
ATOM 4635 N NE1 . TRP D 4 173 ? 367.208 368.427 480.885 1.00 56.35  ? 173 TRP B NE1 1 
ATOM 4636 C CE2 . TRP D 4 173 ? 366.163 368.664 481.732 1.00 56.35  ? 173 TRP B CE2 1 
ATOM 4637 C CE3 . TRP D 4 173 ? 363.856 369.315 481.577 1.00 56.35  ? 173 TRP B CE3 1 
ATOM 4638 C CZ2 . TRP D 4 173 ? 366.096 368.591 483.107 1.00 56.35  ? 173 TRP B CZ2 1 
ATOM 4639 C CZ3 . TRP D 4 173 ? 363.791 369.245 482.938 1.00 56.35  ? 173 TRP B CZ3 1 
ATOM 4640 C CH2 . TRP D 4 173 ? 364.901 368.886 483.692 1.00 56.35  ? 173 TRP B CH2 1 
ATOM 4641 N N   . ASN D 4 174 ? 364.989 365.919 478.007 1.00 56.95  ? 174 ASN B N   1 
ATOM 4642 C CA  . ASN D 4 174 ? 365.757 364.798 477.504 1.00 56.95  ? 174 ASN B CA  1 
ATOM 4643 C C   . ASN D 4 174 ? 364.881 363.696 476.946 1.00 56.95  ? 174 ASN B C   1 
ATOM 4644 O O   . ASN D 4 174 ? 365.412 362.724 476.409 1.00 56.95  ? 174 ASN B O   1 
ATOM 4645 C CB  . ASN D 4 174 ? 366.652 364.234 478.601 1.00 56.95  ? 174 ASN B CB  1 
ATOM 4646 C CG  . ASN D 4 174 ? 367.838 365.107 478.870 1.00 56.95  ? 174 ASN B CG  1 
ATOM 4647 O OD1 . ASN D 4 174 ? 368.212 365.327 480.012 1.00 56.95  ? 174 ASN B OD1 1 
ATOM 4648 N ND2 . ASN D 4 174 ? 368.433 365.627 477.815 1.00 56.95  ? 174 ASN B ND2 1 
ATOM 4649 N N   . ALA D 4 175 ? 363.561 363.823 477.081 1.00 59.14  ? 175 ALA B N   1 
ATOM 4650 C CA  . ALA D 4 175 ? 362.542 362.901 476.577 1.00 59.14  ? 175 ALA B CA  1 
ATOM 4651 C C   . ALA D 4 175 ? 362.693 361.492 477.119 1.00 59.14  ? 175 ALA B C   1 
ATOM 4652 O O   . ALA D 4 175 ? 362.276 360.537 476.471 1.00 59.14  ? 175 ALA B O   1 
ATOM 4653 C CB  . ALA D 4 175 ? 362.506 362.869 475.047 1.00 59.14  ? 175 ALA B CB  1 
ATOM 4654 N N   . GLY D 4 176 ? 363.301 361.330 478.289 1.00 60.29  ? 176 GLY B N   1 
ATOM 4655 C CA  . GLY D 4 176 ? 363.452 360.032 478.909 1.00 60.29  ? 176 GLY B CA  1 
ATOM 4656 C C   . GLY D 4 176 ? 364.419 359.084 478.241 1.00 60.29  ? 176 GLY B C   1 
ATOM 4657 O O   . GLY D 4 176 ? 364.601 357.973 478.739 1.00 60.29  ? 176 GLY B O   1 
ATOM 4658 N N   . MET D 4 177 ? 365.044 359.474 477.132 1.00 62.42  ? 177 MET B N   1 
ATOM 4659 C CA  . MET D 4 177 ? 365.951 358.610 476.392 1.00 62.42  ? 177 MET B CA  1 
ATOM 4660 C C   . MET D 4 177 ? 367.358 359.174 476.320 1.00 62.42  ? 177 MET B C   1 
ATOM 4661 O O   . MET D 4 177 ? 368.203 358.601 475.633 1.00 62.42  ? 177 MET B O   1 
ATOM 4662 C CB  . MET D 4 177 ? 365.419 358.367 474.980 1.00 62.42  ? 177 MET B CB  1 
ATOM 4663 C CG  . MET D 4 177 ? 363.946 358.059 474.931 1.00 62.42  ? 177 MET B CG  1 
ATOM 4664 S SD  . MET D 4 177 ? 363.383 357.543 473.313 1.00 62.42  ? 177 MET B SD  1 
ATOM 4665 C CE  . MET D 4 177 ? 363.556 359.059 472.402 1.00 62.42  ? 177 MET B CE  1 
ATOM 4666 N N   . GLY D 4 178 ? 367.630 360.283 476.997 1.00 59.46  ? 178 GLY B N   1 
ATOM 4667 C CA  . GLY D 4 178 ? 368.970 360.832 477.021 1.00 59.46  ? 178 GLY B CA  1 
ATOM 4668 C C   . GLY D 4 178 ? 369.384 361.541 475.758 1.00 59.46  ? 178 GLY B C   1 
ATOM 4669 O O   . GLY D 4 178 ? 370.496 361.337 475.282 1.00 59.46  ? 178 GLY B O   1 
ATOM 4670 N N   . VAL D 4 179 ? 368.526 362.388 475.212 1.00 57.84  ? 179 VAL B N   1 
ATOM 4671 C CA  . VAL D 4 179 ? 368.705 362.917 473.873 1.00 57.84  ? 179 VAL B CA  1 
ATOM 4672 C C   . VAL D 4 179 ? 368.169 364.344 473.870 1.00 57.84  ? 179 VAL B C   1 
ATOM 4673 O O   . VAL D 4 179 ? 367.536 364.782 474.824 1.00 57.84  ? 179 VAL B O   1 
ATOM 4674 C CB  . VAL D 4 179 ? 367.978 362.019 472.855 1.00 57.84  ? 179 VAL B CB  1 
ATOM 4675 C CG1 . VAL D 4 179 ? 366.490 362.301 472.831 1.00 57.84  ? 179 VAL B CG1 1 
ATOM 4676 C CG2 . VAL D 4 179 ? 368.606 362.078 471.517 1.00 57.84  ? 179 VAL B CG2 1 
ATOM 4677 N N   . GLY D 4 180 ? 368.453 365.093 472.811 1.00 56.67  ? 180 GLY B N   1 
ATOM 4678 C CA  . GLY D 4 180 ? 367.848 366.406 472.680 1.00 56.67  ? 180 GLY B CA  1 
ATOM 4679 C C   . GLY D 4 180 ? 366.403 366.289 472.231 1.00 56.67  ? 180 GLY B C   1 
ATOM 4680 O O   . GLY D 4 180 ? 366.098 365.670 471.214 1.00 56.67  ? 180 GLY B O   1 
ATOM 4681 N N   . VAL D 4 181 ? 365.498 366.891 473.002 1.00 53.93  ? 181 VAL B N   1 
ATOM 4682 C CA  . VAL D 4 181 ? 364.078 366.747 472.696 1.00 53.93  ? 181 VAL B CA  1 
ATOM 4683 C C   . VAL D 4 181 ? 363.677 367.579 471.488 1.00 53.93  ? 181 VAL B C   1 
ATOM 4684 O O   . VAL D 4 181 ? 362.641 367.312 470.875 1.00 53.93  ? 181 VAL B O   1 
ATOM 4685 C CB  . VAL D 4 181 ? 363.223 367.093 473.930 1.00 53.93  ? 181 VAL B CB  1 
ATOM 4686 C CG1 . VAL D 4 181 ? 363.094 368.571 474.113 1.00 53.93  ? 181 VAL B CG1 1 
ATOM 4687 C CG2 . VAL D 4 181 ? 361.860 366.442 473.865 1.00 53.93  ? 181 VAL B CG2 1 
ATOM 4688 N N   . GLY D 4 182 ? 364.483 368.560 471.093 1.00 53.74  ? 182 GLY B N   1 
ATOM 4689 C CA  . GLY D 4 182 ? 364.183 369.283 469.878 1.00 53.74  ? 182 GLY B CA  1 
ATOM 4690 C C   . GLY D 4 182 ? 364.465 368.473 468.636 1.00 53.74  ? 182 GLY B C   1 
ATOM 4691 O O   . GLY D 4 182 ? 363.892 368.734 467.581 1.00 53.74  ? 182 GLY B O   1 
ATOM 4692 N N   . ASN D 4 183 ? 365.336 367.483 468.741 1.00 53.21  ? 183 ASN B N   1 
ATOM 4693 C CA  . ASN D 4 183 ? 365.699 366.638 467.618 1.00 53.21  ? 183 ASN B CA  1 
ATOM 4694 C C   . ASN D 4 183 ? 364.788 365.448 467.458 1.00 53.21  ? 183 ASN B C   1 
ATOM 4695 O O   . ASN D 4 183 ? 365.102 364.553 466.677 1.00 53.21  ? 183 ASN B O   1 
ATOM 4696 C CB  . ASN D 4 183 ? 367.132 366.148 467.770 1.00 53.21  ? 183 ASN B CB  1 
ATOM 4697 C CG  . ASN D 4 183 ? 368.100 367.268 467.916 1.00 53.21  ? 183 ASN B CG  1 
ATOM 4698 O OD1 . ASN D 4 183 ? 367.835 368.379 467.485 1.00 53.21  ? 183 ASN B OD1 1 
ATOM 4699 N ND2 . ASN D 4 183 ? 369.237 366.991 468.526 1.00 53.21  ? 183 ASN B ND2 1 
ATOM 4700 N N   . LEU D 4 184 ? 363.656 365.415 468.145 1.00 50.02  ? 184 LEU B N   1 
ATOM 4701 C CA  . LEU D 4 184 ? 362.724 364.309 468.016 1.00 50.02  ? 184 LEU B CA  1 
ATOM 4702 C C   . LEU D 4 184 ? 361.933 364.347 466.724 1.00 50.02  ? 184 LEU B C   1 
ATOM 4703 O O   . LEU D 4 184 ? 361.103 363.468 466.510 1.00 50.02  ? 184 LEU B O   1 
ATOM 4704 C CB  . LEU D 4 184 ? 361.754 364.300 469.190 1.00 50.02  ? 184 LEU B CB  1 
ATOM 4705 C CG  . LEU D 4 184 ? 362.150 363.487 470.410 1.00 50.02  ? 184 LEU B CG  1 
ATOM 4706 C CD1 . LEU D 4 184 ? 361.029 363.509 471.396 1.00 50.02  ? 184 LEU B CD1 1 
ATOM 4707 C CD2 . LEU D 4 184 ? 362.450 362.083 470.017 1.00 50.02  ? 184 LEU B CD2 1 
ATOM 4708 N N   . THR D 4 185 ? 362.162 365.321 465.859 1.00 52.17  ? 185 THR B N   1 
ATOM 4709 C CA  . THR D 4 185 ? 361.421 365.427 464.617 1.00 52.17  ? 185 THR B CA  1 
ATOM 4710 C C   . THR D 4 185 ? 361.946 364.505 463.532 1.00 52.17  ? 185 THR B C   1 
ATOM 4711 O O   . THR D 4 185 ? 361.440 364.553 462.411 1.00 52.17  ? 185 THR B O   1 
ATOM 4712 C CB  . THR D 4 185 ? 361.462 366.856 464.103 1.00 52.17  ? 185 THR B CB  1 
ATOM 4713 O OG1 . THR D 4 185 ? 362.792 367.160 463.690 1.00 52.17  ? 185 THR B OG1 1 
ATOM 4714 C CG2 . THR D 4 185 ? 361.081 367.815 465.195 1.00 52.17  ? 185 THR B CG2 1 
ATOM 4715 N N   . ILE D 4 186 ? 362.950 363.682 463.816 1.00 52.01  ? 186 ILE B N   1 
ATOM 4716 C CA  . ILE D 4 186 ? 363.416 362.760 462.794 1.00 52.01  ? 186 ILE B CA  1 
ATOM 4717 C C   . ILE D 4 186 ? 362.513 361.537 462.734 1.00 52.01  ? 186 ILE B C   1 
ATOM 4718 O O   . ILE D 4 186 ? 362.477 360.831 461.723 1.00 52.01  ? 186 ILE B O   1 
ATOM 4719 C CB  . ILE D 4 186 ? 364.887 362.406 463.047 1.00 52.01  ? 186 ILE B CB  1 
ATOM 4720 C CG1 . ILE D 4 186 ? 365.520 361.808 461.799 1.00 52.01  ? 186 ILE B CG1 1 
ATOM 4721 C CG2 . ILE D 4 186 ? 365.020 361.496 464.196 1.00 52.01  ? 186 ILE B CG2 1 
ATOM 4722 C CD1 . ILE D 4 186 ? 366.962 361.592 461.927 1.00 52.01  ? 186 ILE B CD1 1 
ATOM 4723 N N   . PHE D 4 187 ? 361.742 361.284 463.780 1.00 53.96  ? 187 PHE B N   1 
ATOM 4724 C CA  . PHE D 4 187 ? 360.734 360.256 463.722 1.00 53.96  ? 187 PHE B CA  1 
ATOM 4725 C C   . PHE D 4 187 ? 359.519 360.811 462.996 1.00 53.96  ? 187 PHE B C   1 
ATOM 4726 O O   . PHE D 4 187 ? 359.378 362.026 462.877 1.00 53.96  ? 187 PHE B O   1 
ATOM 4727 C CB  . PHE D 4 187 ? 360.389 359.805 465.131 1.00 53.96  ? 187 PHE B CB  1 
ATOM 4728 C CG  . PHE D 4 187 ? 361.549 359.240 465.874 1.00 53.96  ? 187 PHE B CG  1 
ATOM 4729 C CD1 . PHE D 4 187 ? 362.060 358.007 465.540 1.00 53.96  ? 187 PHE B CD1 1 
ATOM 4730 C CD2 . PHE D 4 187 ? 362.134 359.940 466.898 1.00 53.96  ? 187 PHE B CD2 1 
ATOM 4731 C CE1 . PHE D 4 187 ? 363.121 357.489 466.220 1.00 53.96  ? 187 PHE B CE1 1 
ATOM 4732 C CE2 . PHE D 4 187 ? 363.199 359.422 467.577 1.00 53.96  ? 187 PHE B CE2 1 
ATOM 4733 C CZ  . PHE D 4 187 ? 363.686 358.199 467.239 1.00 53.96  ? 187 PHE B CZ  1 
ATOM 4734 N N   . PRO D 4 188 ? 358.657 359.951 462.442 1.00 57.16  ? 188 PRO B N   1 
ATOM 4735 C CA  . PRO D 4 188 ? 357.420 360.454 461.831 1.00 57.16  ? 188 PRO B CA  1 
ATOM 4736 C C   . PRO D 4 188 ? 356.499 361.147 462.820 1.00 57.16  ? 188 PRO B C   1 
ATOM 4737 O O   . PRO D 4 188 ? 356.090 360.565 463.824 1.00 57.16  ? 188 PRO B O   1 
ATOM 4738 C CB  . PRO D 4 188 ? 356.786 359.192 461.239 1.00 57.16  ? 188 PRO B CB  1 
ATOM 4739 C CG  . PRO D 4 188 ? 357.452 358.082 461.887 1.00 57.16  ? 188 PRO B CG  1 
ATOM 4740 C CD  . PRO D 4 188 ? 358.831 358.519 462.166 1.00 57.16  ? 188 PRO B CD  1 
ATOM 4741 N N   . HIS D 4 189 ? 356.185 362.405 462.541 1.00 55.32  ? 189 HIS B N   1 
ATOM 4742 C CA  . HIS D 4 189 ? 355.587 363.305 463.510 1.00 55.32  ? 189 HIS B CA  1 
ATOM 4743 C C   . HIS D 4 189 ? 354.599 364.233 462.821 1.00 55.32  ? 189 HIS B C   1 
ATOM 4744 O O   . HIS D 4 189 ? 354.393 364.167 461.609 1.00 55.32  ? 189 HIS B O   1 
ATOM 4745 C CB  . HIS D 4 189 ? 356.665 364.118 464.225 1.00 55.32  ? 189 HIS B CB  1 
ATOM 4746 C CG  . HIS D 4 189 ? 357.310 365.152 463.360 1.00 55.32  ? 189 HIS B CG  1 
ATOM 4747 N ND1 . HIS D 4 189 ? 357.893 364.854 462.150 1.00 55.32  ? 189 HIS B ND1 1 
ATOM 4748 C CD2 . HIS D 4 189 ? 357.466 366.483 463.533 1.00 55.32  ? 189 HIS B CD2 1 
ATOM 4749 C CE1 . HIS D 4 189 ? 358.377 365.957 461.613 1.00 55.32  ? 189 HIS B CE1 1 
ATOM 4750 N NE2 . HIS D 4 189 ? 358.133 366.960 462.433 1.00 55.32  ? 189 HIS B NE2 1 
ATOM 4751 N N   . GLN D 4 190 ? 353.995 365.113 463.615 1.00 55.80  ? 190 GLN B N   1 
ATOM 4752 C CA  . GLN D 4 190 ? 353.046 366.107 463.134 1.00 55.80  ? 190 GLN B CA  1 
ATOM 4753 C C   . GLN D 4 190 ? 352.914 367.169 464.210 1.00 55.80  ? 190 GLN B C   1 
ATOM 4754 O O   . GLN D 4 190 ? 352.887 366.834 465.392 1.00 55.80  ? 190 GLN B O   1 
ATOM 4755 C CB  . GLN D 4 190 ? 351.686 365.477 462.842 1.00 55.80  ? 190 GLN B CB  1 
ATOM 4756 C CG  . GLN D 4 190 ? 350.649 366.429 462.292 1.00 55.80  ? 190 GLN B CG  1 
ATOM 4757 C CD  . GLN D 4 190 ? 350.701 366.577 460.797 1.00 55.80  ? 190 GLN B CD  1 
ATOM 4758 O OE1 . GLN D 4 190 ? 351.241 367.548 460.274 1.00 55.80  ? 190 GLN B OE1 1 
ATOM 4759 N NE2 . GLN D 4 190 ? 350.108 365.628 460.096 1.00 55.80  ? 190 GLN B NE2 1 
ATOM 4760 N N   . TRP D 4 191 ? 352.852 368.435 463.814 1.00 49.00  ? 191 TRP B N   1 
ATOM 4761 C CA  . TRP D 4 191 ? 352.672 369.521 464.763 1.00 49.00  ? 191 TRP B CA  1 
ATOM 4762 C C   . TRP D 4 191 ? 351.203 369.889 464.860 1.00 49.00  ? 191 TRP B C   1 
ATOM 4763 O O   . TRP D 4 191 ? 350.480 369.862 463.864 1.00 49.00  ? 191 TRP B O   1 
ATOM 4764 C CB  . TRP D 4 191 ? 353.476 370.752 464.350 1.00 49.00  ? 191 TRP B CB  1 
ATOM 4765 C CG  . TRP D 4 191 ? 354.937 370.608 464.524 1.00 49.00  ? 191 TRP B CG  1 
ATOM 4766 C CD1 . TRP D 4 191 ? 355.818 370.184 463.599 1.00 49.00  ? 191 TRP B CD1 1 
ATOM 4767 C CD2 . TRP D 4 191 ? 355.694 370.889 465.699 1.00 49.00  ? 191 TRP B CD2 1 
ATOM 4768 N NE1 . TRP D 4 191 ? 357.080 370.175 464.116 1.00 49.00  ? 191 TRP B NE1 1 
ATOM 4769 C CE2 . TRP D 4 191 ? 357.027 370.607 465.410 1.00 49.00  ? 191 TRP B CE2 1 
ATOM 4770 C CE3 . TRP D 4 191 ? 355.371 371.349 466.968 1.00 49.00  ? 191 TRP B CE3 1 
ATOM 4771 C CZ2 . TRP D 4 191 ? 358.032 370.763 466.339 1.00 49.00  ? 191 TRP B CZ2 1 
ATOM 4772 C CZ3 . TRP D 4 191 ? 356.374 371.506 467.886 1.00 49.00  ? 191 TRP B CZ3 1 
ATOM 4773 C CH2 . TRP D 4 191 ? 357.683 371.219 467.570 1.00 49.00  ? 191 TRP B CH2 1 
ATOM 4774 N N   . ILE D 4 192 ? 350.763 370.230 466.064 1.00 51.13  ? 192 ILE B N   1 
ATOM 4775 C CA  . ILE D 4 192 ? 349.421 370.740 466.299 1.00 51.13  ? 192 ILE B CA  1 
ATOM 4776 C C   . ILE D 4 192 ? 349.565 372.134 466.876 1.00 51.13  ? 192 ILE B C   1 
ATOM 4777 O O   . ILE D 4 192 ? 349.874 372.297 468.059 1.00 51.13  ? 192 ILE B O   1 
ATOM 4778 C CB  . ILE D 4 192 ? 348.614 369.847 467.240 1.00 51.13  ? 192 ILE B CB  1 
ATOM 4779 C CG1 . ILE D 4 192 ? 348.432 368.471 466.633 1.00 51.13  ? 192 ILE B CG1 1 
ATOM 4780 C CG2 . ILE D 4 192 ? 347.262 370.449 467.486 1.00 51.13  ? 192 ILE B CG2 1 
ATOM 4781 C CD1 . ILE D 4 192 ? 347.645 367.550 467.499 1.00 51.13  ? 192 ILE B CD1 1 
ATOM 4782 N N   . ASN D 4 193 ? 349.353 373.138 466.043 1.00 53.50  ? 193 ASN B N   1 
ATOM 4783 C CA  . ASN D 4 193 ? 349.374 374.532 466.449 1.00 53.50  ? 193 ASN B CA  1 
ATOM 4784 C C   . ASN D 4 193 ? 347.931 374.985 466.547 1.00 53.50  ? 193 ASN B C   1 
ATOM 4785 O O   . ASN D 4 193 ? 347.198 374.904 465.562 1.00 53.50  ? 193 ASN B O   1 
ATOM 4786 C CB  . ASN D 4 193 ? 350.147 375.364 465.433 1.00 53.50  ? 193 ASN B CB  1 
ATOM 4787 C CG  . ASN D 4 193 ? 350.388 376.764 465.892 1.00 53.50  ? 193 ASN B CG  1 
ATOM 4788 O OD1 . ASN D 4 193 ? 350.194 377.083 467.054 1.00 53.50  ? 193 ASN B OD1 1 
ATOM 4789 N ND2 . ASN D 4 193 ? 350.828 377.615 464.984 1.00 53.50  ? 193 ASN B ND2 1 
ATOM 4790 N N   . LEU D 4 194 ? 347.515 375.441 467.729 1.00 51.78  ? 194 LEU B N   1 
ATOM 4791 C CA  . LEU D 4 194 ? 346.111 375.769 467.949 1.00 51.78  ? 194 LEU B CA  1 
ATOM 4792 C C   . LEU D 4 194 ? 345.647 376.958 467.127 1.00 51.78  ? 194 LEU B C   1 
ATOM 4793 O O   . LEU D 4 194 ? 344.447 377.084 466.871 1.00 51.78  ? 194 LEU B O   1 
ATOM 4794 C CB  . LEU D 4 194 ? 345.860 376.056 469.422 1.00 51.78  ? 194 LEU B CB  1 
ATOM 4795 C CG  . LEU D 4 194 ? 345.880 374.881 470.380 1.00 51.78  ? 194 LEU B CG  1 
ATOM 4796 C CD1 . LEU D 4 194 ? 345.514 375.367 471.747 1.00 51.78  ? 194 LEU B CD1 1 
ATOM 4797 C CD2 . LEU D 4 194 ? 344.931 373.810 469.933 1.00 51.78  ? 194 LEU B CD2 1 
ATOM 4798 N N   . ARG D 4 195 ? 346.572 377.814 466.709 1.00 56.95  ? 195 ARG B N   1 
ATOM 4799 C CA  . ARG D 4 195 ? 346.237 378.963 465.884 1.00 56.95  ? 195 ARG B CA  1 
ATOM 4800 C C   . ARG D 4 195 ? 345.766 378.541 464.501 1.00 56.95  ? 195 ARG B C   1 
ATOM 4801 O O   . ARG D 4 195 ? 344.841 379.140 463.949 1.00 56.95  ? 195 ARG B O   1 
ATOM 4802 C CB  . ARG D 4 195 ? 347.458 379.864 465.797 1.00 56.95  ? 195 ARG B CB  1 
ATOM 4803 C CG  . ARG D 4 195 ? 347.331 381.002 464.872 1.00 56.95  ? 195 ARG B CG  1 
ATOM 4804 C CD  . ARG D 4 195 ? 348.668 381.580 464.603 1.00 56.95  ? 195 ARG B CD  1 
ATOM 4805 N NE  . ARG D 4 195 ? 348.565 382.648 463.633 1.00 56.95  ? 195 ARG B NE  1 
ATOM 4806 C CZ  . ARG D 4 195 ? 348.413 383.916 463.963 1.00 56.95  ? 195 ARG B CZ  1 
ATOM 4807 N NH1 . ARG D 4 195 ? 348.357 384.256 465.235 1.00 56.95  ? 195 ARG B NH1 1 
ATOM 4808 N NH2 . ARG D 4 195 ? 348.323 384.839 463.025 1.00 56.95  ? 195 ARG B NH2 1 
ATOM 4809 N N   . THR D 4 196 ? 346.359 377.499 463.940 1.00 58.89  ? 196 THR B N   1 
ATOM 4810 C CA  . THR D 4 196 ? 346.051 377.079 462.583 1.00 58.89  ? 196 THR B CA  1 
ATOM 4811 C C   . THR D 4 196 ? 345.509 375.669 462.462 1.00 58.89  ? 196 THR B C   1 
ATOM 4812 O O   . THR D 4 196 ? 344.741 375.403 461.541 1.00 58.89  ? 196 THR B O   1 
ATOM 4813 C CB  . THR D 4 196 ? 347.293 377.183 461.693 1.00 58.89  ? 196 THR B CB  1 
ATOM 4814 O OG1 . THR D 4 196 ? 347.050 376.494 460.466 1.00 58.89  ? 196 THR B OG1 1 
ATOM 4815 C CG2 . THR D 4 196 ? 348.488 376.577 462.361 1.00 58.89  ? 196 THR B CG2 1 
ATOM 4816 N N   . ASN D 4 197 ? 345.878 374.765 463.354 1.00 60.00  ? 197 ASN B N   1 
ATOM 4817 C CA  . ASN D 4 197 ? 345.607 373.348 463.196 1.00 60.00  ? 197 ASN B CA  1 
ATOM 4818 C C   . ASN D 4 197 ? 344.776 372.845 464.358 1.00 60.00  ? 197 ASN B C   1 
ATOM 4819 O O   . ASN D 4 197 ? 344.663 373.482 465.404 1.00 60.00  ? 197 ASN B O   1 
ATOM 4820 C CB  . ASN D 4 197 ? 346.910 372.558 463.113 1.00 60.00  ? 197 ASN B CB  1 
ATOM 4821 C CG  . ASN D 4 197 ? 346.761 371.317 462.318 1.00 60.00  ? 197 ASN B CG  1 
ATOM 4822 O OD1 . ASN D 4 197 ? 345.724 371.097 461.707 1.00 60.00  ? 197 ASN B OD1 1 
ATOM 4823 N ND2 . ASN D 4 197 ? 347.785 370.482 462.317 1.00 60.00  ? 197 ASN B ND2 1 
ATOM 4824 N N   . ASN D 4 198 ? 344.200 371.684 464.160 1.00 63.45  ? 198 ASN B N   1 
ATOM 4825 C CA  . ASN D 4 198 ? 343.301 371.120 465.152 1.00 63.45  ? 198 ASN B CA  1 
ATOM 4826 C C   . ASN D 4 198 ? 343.628 369.685 465.517 1.00 63.45  ? 198 ASN B C   1 
ATOM 4827 O O   . ASN D 4 198 ? 343.401 369.297 466.664 1.00 63.45  ? 198 ASN B O   1 
ATOM 4828 C CB  . ASN D 4 198 ? 341.872 371.167 464.621 1.00 63.45  ? 198 ASN B CB  1 
ATOM 4829 C CG  . ASN D 4 198 ? 340.854 371.043 465.698 1.00 63.45  ? 198 ASN B CG  1 
ATOM 4830 O OD1 . ASN D 4 198 ? 341.175 371.137 466.871 1.00 63.45  ? 198 ASN B OD1 1 
ATOM 4831 N ND2 . ASN D 4 198 ? 339.616 370.784 465.312 1.00 63.45  ? 198 ASN B ND2 1 
ATOM 4832 N N   . SER D 4 199 ? 344.183 368.898 464.603 1.00 60.00  ? 199 SER B N   1 
ATOM 4833 C CA  . SER D 4 199 ? 344.335 367.472 464.788 1.00 60.00  ? 199 SER B CA  1 
ATOM 4834 C C   . SER D 4 199 ? 345.621 367.001 464.136 1.00 60.00  ? 199 SER B C   1 
ATOM 4835 O O   . SER D 4 199 ? 346.290 367.745 463.422 1.00 60.00  ? 199 SER B O   1 
ATOM 4836 C CB  . SER D 4 199 ? 343.163 366.718 464.185 1.00 60.00  ? 199 SER B CB  1 
ATOM 4837 O OG  . SER D 4 199 ? 342.927 367.173 462.872 1.00 60.00  ? 199 SER B OG  1 
ATOM 4838 N N   . ALA D 4 200 ? 345.938 365.734 464.369 1.00 59.04  ? 200 ALA B N   1 
ATOM 4839 C CA  . ALA D 4 200 ? 347.062 365.069 463.738 1.00 59.04  ? 200 ALA B CA  1 
ATOM 4840 C C   . ALA D 4 200 ? 346.620 363.678 463.326 1.00 59.04  ? 200 ALA B C   1 
ATOM 4841 O O   . ALA D 4 200 ? 345.667 363.135 463.881 1.00 59.04  ? 200 ALA B O   1 
ATOM 4842 C CB  . ALA D 4 200 ? 348.257 364.983 464.678 1.00 59.04  ? 200 ALA B CB  1 
ATOM 4843 N N   . THR D 4 201 ? 347.292 363.109 462.331 1.00 63.78  ? 201 THR B N   1 
ATOM 4844 C CA  . THR D 4 201 ? 346.990 361.750 461.903 1.00 63.78  ? 201 THR B CA  1 
ATOM 4845 C C   . THR D 4 201 ? 348.261 361.064 461.436 1.00 63.78  ? 201 THR B C   1 
ATOM 4846 O O   . THR D 4 201 ? 348.967 361.591 460.577 1.00 63.78  ? 201 THR B O   1 
ATOM 4847 C CB  . THR D 4 201 ? 345.953 361.724 460.780 1.00 63.78  ? 201 THR B CB  1 
ATOM 4848 O OG1 . THR D 4 201 ? 344.817 362.516 461.145 1.00 63.78  ? 201 THR B OG1 1 
ATOM 4849 C CG2 . THR D 4 201 ? 345.489 360.303 460.535 1.00 63.78  ? 201 THR B CG2 1 
ATOM 4850 N N   . LEU D 4 202 ? 348.537 359.887 461.987 1.00 62.21  ? 202 LEU B N   1 
ATOM 4851 C CA  . LEU D 4 202 ? 349.732 359.121 461.675 1.00 62.21  ? 202 LEU B CA  1 
ATOM 4852 C C   . LEU D 4 202 ? 349.324 357.745 461.187 1.00 62.21  ? 202 LEU B C   1 
ATOM 4853 O O   . LEU D 4 202 ? 348.342 357.178 461.659 1.00 62.21  ? 202 LEU B O   1 
ATOM 4854 C CB  . LEU D 4 202 ? 350.626 358.963 462.898 1.00 62.21  ? 202 LEU B CB  1 
ATOM 4855 C CG  . LEU D 4 202 ? 351.177 360.212 463.570 1.00 62.21  ? 202 LEU B CG  1 
ATOM 4856 C CD1 . LEU D 4 202 ? 351.823 359.838 464.859 1.00 62.21  ? 202 LEU B CD1 1 
ATOM 4857 C CD2 . LEU D 4 202 ? 352.187 360.831 462.702 1.00 62.21  ? 202 LEU B CD2 1 
ATOM 4858 N N   . VAL D 4 203 ? 350.074 357.211 460.229 1.00 66.01  ? 203 VAL B N   1 
ATOM 4859 C CA  . VAL D 4 203 ? 349.890 355.848 459.741 1.00 66.01  ? 203 VAL B CA  1 
ATOM 4860 C C   . VAL D 4 203 ? 351.240 355.156 459.805 1.00 66.01  ? 203 VAL B C   1 
ATOM 4861 O O   . VAL D 4 203 ? 352.117 355.436 458.984 1.00 66.01  ? 203 VAL B O   1 
ATOM 4862 C CB  . VAL D 4 203 ? 349.341 355.811 458.309 1.00 66.01  ? 203 VAL B CB  1 
ATOM 4863 C CG1 . VAL D 4 203 ? 349.215 354.393 457.844 1.00 66.01  ? 203 VAL B CG1 1 
ATOM 4864 C CG2 . VAL D 4 203 ? 348.008 356.491 458.228 1.00 66.01  ? 203 VAL B CG2 1 
ATOM 4865 N N   . MET D 4 204 ? 351.410 354.252 460.762 1.00 67.59  ? 204 MET B N   1 
ATOM 4866 C CA  . MET D 4 204 ? 352.714 353.700 461.060 1.00 67.59  ? 204 MET B CA  1 
ATOM 4867 C C   . MET D 4 204 ? 352.813 352.251 460.613 1.00 67.59  ? 204 MET B C   1 
ATOM 4868 O O   . MET D 4 204 ? 352.041 351.410 461.088 1.00 67.59  ? 204 MET B O   1 
ATOM 4869 C CB  . MET D 4 204 ? 352.985 353.785 462.542 1.00 67.59  ? 204 MET B CB  1 
ATOM 4870 C CG  . MET D 4 204 ? 353.090 355.182 463.036 1.00 67.59  ? 204 MET B CG  1 
ATOM 4871 S SD  . MET D 4 204 ? 354.636 355.908 462.523 1.00 67.59  ? 204 MET B SD  1 
ATOM 4872 C CE  . MET D 4 204 ? 355.787 354.739 463.218 1.00 67.59  ? 204 MET B CE  1 
ATOM 4873 N N   . PRO D 4 205 ? 353.758 351.907 459.758 1.00 66.55  ? 205 PRO B N   1 
ATOM 4874 C CA  . PRO D 4 205 ? 353.881 350.531 459.288 1.00 66.55  ? 205 PRO B CA  1 
ATOM 4875 C C   . PRO D 4 205 ? 354.563 349.673 460.345 1.00 66.55  ? 205 PRO B C   1 
ATOM 4876 O O   . PRO D 4 205 ? 354.958 350.144 461.402 1.00 66.55  ? 205 PRO B O   1 
ATOM 4877 C CB  . PRO D 4 205 ? 354.740 350.683 458.042 1.00 66.55  ? 205 PRO B CB  1 
ATOM 4878 C CG  . PRO D 4 205 ? 355.608 351.811 458.362 1.00 66.55  ? 205 PRO B CG  1 
ATOM 4879 C CD  . PRO D 4 205 ? 354.826 352.754 459.214 1.00 66.55  ? 205 PRO B CD  1 
ATOM 4880 N N   . TYR D 4 206 ? 354.701 348.392 460.039 1.00 69.40  ? 206 TYR B N   1 
ATOM 4881 C CA  . TYR D 4 206 ? 355.280 347.447 460.980 1.00 69.40  ? 206 TYR B CA  1 
ATOM 4882 C C   . TYR D 4 206 ? 356.796 347.493 460.870 1.00 69.40  ? 206 TYR B C   1 
ATOM 4883 O O   . TYR D 4 206 ? 357.357 347.136 459.831 1.00 69.40  ? 206 TYR B O   1 
ATOM 4884 C CB  . TYR D 4 206 ? 354.767 346.039 460.717 1.00 69.40  ? 206 TYR B CB  1 
ATOM 4885 C CG  . TYR D 4 206 ? 355.325 345.037 461.678 1.00 69.40  ? 206 TYR B CG  1 
ATOM 4886 C CD1 . TYR D 4 206 ? 354.975 345.068 463.011 1.00 69.40  ? 206 TYR B CD1 1 
ATOM 4887 C CD2 . TYR D 4 206 ? 356.214 344.069 461.255 1.00 69.40  ? 206 TYR B CD2 1 
ATOM 4888 C CE1 . TYR D 4 206 ? 355.487 344.162 463.892 1.00 69.40  ? 206 TYR B CE1 1 
ATOM 4889 C CE2 . TYR D 4 206 ? 356.730 343.161 462.129 1.00 69.40  ? 206 TYR B CE2 1 
ATOM 4890 C CZ  . TYR D 4 206 ? 356.363 343.214 463.443 1.00 69.40  ? 206 TYR B CZ  1 
ATOM 4891 O OH  . TYR D 4 206 ? 356.880 342.307 464.323 1.00 69.40  ? 206 TYR B OH  1 
ATOM 4892 N N   . ILE D 4 207 ? 357.455 347.928 461.939 1.00 62.60  ? 207 ILE B N   1 
ATOM 4893 C CA  . ILE D 4 207 ? 358.899 348.120 461.962 1.00 62.60  ? 207 ILE B CA  1 
ATOM 4894 C C   . ILE D 4 207 ? 359.461 347.164 463.000 1.00 62.60  ? 207 ILE B C   1 
ATOM 4895 O O   . ILE D 4 207 ? 359.236 347.350 464.199 1.00 62.60  ? 207 ILE B O   1 
ATOM 4896 C CB  . ILE D 4 207 ? 359.280 349.565 462.287 1.00 62.60  ? 207 ILE B CB  1 
ATOM 4897 C CG1 . ILE D 4 207 ? 358.313 350.535 461.623 1.00 62.60  ? 207 ILE B CG1 1 
ATOM 4898 C CG2 . ILE D 4 207 ? 360.675 349.856 461.825 1.00 62.60  ? 207 ILE B CG2 1 
ATOM 4899 C CD1 . ILE D 4 207 ? 358.593 351.970 461.926 1.00 62.60  ? 207 ILE B CD1 1 
ATOM 4900 N N   . ASN D 4 208 ? 360.198 346.149 462.552 1.00 61.68  ? 208 ASN B N   1 
ATOM 4901 C CA  . ASN D 4 208 ? 360.876 345.225 463.452 1.00 61.68  ? 208 ASN B CA  1 
ATOM 4902 C C   . ASN D 4 208 ? 361.984 344.516 462.697 1.00 61.68  ? 208 ASN B C   1 
ATOM 4903 O O   . ASN D 4 208 ? 362.014 344.514 461.468 1.00 61.68  ? 208 ASN B O   1 
ATOM 4904 C CB  . ASN D 4 208 ? 359.923 344.194 464.045 1.00 61.68  ? 208 ASN B CB  1 
ATOM 4905 C CG  . ASN D 4 208 ? 360.355 343.740 465.398 1.00 61.68  ? 208 ASN B CG  1 
ATOM 4906 O OD1 . ASN D 4 208 ? 361.472 344.006 465.816 1.00 61.68  ? 208 ASN B OD1 1 
ATOM 4907 N ND2 . ASN D 4 208 ? 359.479 343.049 466.097 1.00 61.68  ? 208 ASN B ND2 1 
ATOM 4908 N N   . SER D 4 209 ? 362.893 343.899 463.452 1.00 60.31  ? 209 SER B N   1 
ATOM 4909 C CA  . SER D 4 209 ? 363.982 343.154 462.832 1.00 60.31  ? 209 SER B CA  1 
ATOM 4910 C C   . SER D 4 209 ? 363.536 341.758 462.426 1.00 60.31  ? 209 SER B C   1 
ATOM 4911 O O   . SER D 4 209 ? 363.894 341.276 461.350 1.00 60.31  ? 209 SER B O   1 
ATOM 4912 C CB  . SER D 4 209 ? 365.177 343.074 463.774 1.00 60.31  ? 209 SER B CB  1 
ATOM 4913 O OG  . SER D 4 209 ? 364.816 342.510 465.013 1.00 60.31  ? 209 SER B OG  1 
ATOM 4914 N N   . VAL D 4 210 ? 362.769 341.086 463.275 1.00 65.84  ? 210 VAL B N   1 
ATOM 4915 C CA  . VAL D 4 210 ? 362.206 339.781 462.943 1.00 65.84  ? 210 VAL B CA  1 
ATOM 4916 C C   . VAL D 4 210 ? 360.862 340.012 462.265 1.00 65.84  ? 210 VAL B C   1 
ATOM 4917 O O   . VAL D 4 210 ? 360.243 341.061 462.483 1.00 65.84  ? 210 VAL B O   1 
ATOM 4918 C CB  . VAL D 4 210 ? 362.079 338.908 464.196 1.00 65.84  ? 210 VAL B CB  1 
ATOM 4919 C CG1 . VAL D 4 210 ? 363.431 338.675 464.778 1.00 65.84  ? 210 VAL B CG1 1 
ATOM 4920 C CG2 . VAL D 4 210 ? 361.204 339.574 465.206 1.00 65.84  ? 210 VAL B CG2 1 
ATOM 4921 N N   . PRO D 4 211 ? 360.372 339.102 461.419 1.00 73.92  ? 211 PRO B N   1 
ATOM 4922 C CA  . PRO D 4 211 ? 359.088 339.351 460.757 1.00 73.92  ? 211 PRO B CA  1 
ATOM 4923 C C   . PRO D 4 211 ? 357.880 339.156 461.649 1.00 73.92  ? 211 PRO B C   1 
ATOM 4924 O O   . PRO D 4 211 ? 356.784 339.579 461.266 1.00 73.92  ? 211 PRO B O   1 
ATOM 4925 C CB  . PRO D 4 211 ? 359.088 338.331 459.621 1.00 73.92  ? 211 PRO B CB  1 
ATOM 4926 C CG  . PRO D 4 211 ? 359.900 337.234 460.134 1.00 73.92  ? 211 PRO B CG  1 
ATOM 4927 C CD  . PRO D 4 211 ? 361.000 337.876 460.903 1.00 73.92  ? 211 PRO B CD  1 
ATOM 4928 N N   . MET D 4 212 ? 358.044 338.538 462.816 1.00 87.22  ? 212 MET B N   1 
ATOM 4929 C CA  . MET D 4 212 ? 356.928 338.211 463.691 1.00 87.22  ? 212 MET B CA  1 
ATOM 4930 C C   . MET D 4 212 ? 357.499 337.907 465.068 1.00 87.22  ? 212 MET B C   1 
ATOM 4931 O O   . MET D 4 212 ? 358.295 336.977 465.205 1.00 87.22  ? 212 MET B O   1 
ATOM 4932 C CB  . MET D 4 212 ? 356.170 337.020 463.121 1.00 87.22  ? 212 MET B CB  1 
ATOM 4933 C CG  . MET D 4 212 ? 355.159 336.410 464.009 1.00 87.22  ? 212 MET B CG  1 
ATOM 4934 S SD  . MET D 4 212 ? 353.947 335.521 463.025 1.00 87.22  ? 212 MET B SD  1 
ATOM 4935 C CE  . MET D 4 212 ? 352.673 336.757 462.837 1.00 87.22  ? 212 MET B CE  1 
ATOM 4936 N N   . ASP D 4 213 ? 357.108 338.678 466.079 1.00 85.60  ? 213 ASP B N   1 
ATOM 4937 C CA  . ASP D 4 213 ? 357.806 338.695 467.359 1.00 85.60  ? 213 ASP B CA  1 
ATOM 4938 C C   . ASP D 4 213 ? 356.887 338.352 468.524 1.00 85.60  ? 213 ASP B C   1 
ATOM 4939 O O   . ASP D 4 213 ? 355.668 338.265 468.388 1.00 85.60  ? 213 ASP B O   1 
ATOM 4940 C CB  . ASP D 4 213 ? 358.424 340.070 467.619 1.00 85.60  ? 213 ASP B CB  1 
ATOM 4941 C CG  . ASP D 4 213 ? 357.377 341.159 467.741 1.00 85.60  ? 213 ASP B CG  1 
ATOM 4942 O OD1 . ASP D 4 213 ? 356.348 341.073 467.042 1.00 85.60  ? 213 ASP B OD1 1 
ATOM 4943 O OD2 . ASP D 4 213 ? 357.582 342.105 468.529 1.00 85.60  ? 213 ASP B OD2 1 
ATOM 4944 N N   . ASN D 4 214 ? 357.507 338.192 469.690 1.00 82.58  ? 214 ASN B N   1 
ATOM 4945 C CA  . ASN D 4 214 ? 356.791 338.009 470.944 1.00 82.58  ? 214 ASN B CA  1 
ATOM 4946 C C   . ASN D 4 214 ? 356.053 339.282 471.331 1.00 82.58  ? 214 ASN B C   1 
ATOM 4947 O O   . ASN D 4 214 ? 356.660 340.304 471.638 1.00 82.58  ? 214 ASN B O   1 
ATOM 4948 C CB  . ASN D 4 214 ? 357.777 337.641 472.053 1.00 82.58  ? 214 ASN B CB  1 
ATOM 4949 C CG  . ASN D 4 214 ? 357.106 337.083 473.288 1.00 82.58  ? 214 ASN B CG  1 
ATOM 4950 O OD1 . ASN D 4 214 ? 356.315 337.752 473.943 1.00 82.58  ? 214 ASN B OD1 1 
ATOM 4951 N ND2 . ASN D 4 214 ? 357.463 335.863 473.643 1.00 82.58  ? 214 ASN B ND2 1 
ATOM 4952 N N   . MET D 4 215 ? 354.731 339.204 471.370 1.00 81.76  ? 215 MET B N   1 
ATOM 4953 C CA  . MET D 4 215 ? 353.915 340.378 471.623 1.00 81.76  ? 215 MET B CA  1 
ATOM 4954 C C   . MET D 4 215 ? 353.744 340.689 473.099 1.00 81.76  ? 215 MET B C   1 
ATOM 4955 O O   . MET D 4 215 ? 353.212 341.750 473.431 1.00 81.76  ? 215 MET B O   1 
ATOM 4956 C CB  . MET D 4 215 ? 352.538 340.218 470.982 1.00 81.76  ? 215 MET B CB  1 
ATOM 4957 C CG  . MET D 4 215 ? 352.542 340.286 469.478 1.00 81.76  ? 215 MET B CG  1 
ATOM 4958 S SD  . MET D 4 215 ? 350.901 340.635 468.840 1.00 81.76  ? 215 MET B SD  1 
ATOM 4959 C CE  . MET D 4 215 ? 350.635 342.270 469.495 1.00 81.76  ? 215 MET B CE  1 
ATOM 4960 N N   . PHE D 4 216 ? 354.166 339.804 473.993 1.00 78.91  ? 216 PHE B N   1 
ATOM 4961 C CA  . PHE D 4 216 ? 354.046 340.039 475.425 1.00 78.91  ? 216 PHE B CA  1 
ATOM 4962 C C   . PHE D 4 216 ? 355.268 340.695 476.024 1.00 78.91  ? 216 PHE B C   1 
ATOM 4963 O O   . PHE D 4 216 ? 355.187 341.253 477.114 1.00 78.91  ? 216 PHE B O   1 
ATOM 4964 C CB  . PHE D 4 216 ? 353.801 338.731 476.169 1.00 78.91  ? 216 PHE B CB  1 
ATOM 4965 C CG  . PHE D 4 216 ? 352.435 338.169 475.978 1.00 78.91  ? 216 PHE B CG  1 
ATOM 4966 C CD1 . PHE D 4 216 ? 351.367 338.667 476.707 1.00 78.91  ? 216 PHE B CD1 1 
ATOM 4967 C CD2 . PHE D 4 216 ? 352.219 337.125 475.094 1.00 78.91  ? 216 PHE B CD2 1 
ATOM 4968 C CE1 . PHE D 4 216 ? 350.108 338.150 476.548 1.00 78.91  ? 216 PHE B CE1 1 
ATOM 4969 C CE2 . PHE D 4 216 ? 350.959 336.602 474.927 1.00 78.91  ? 216 PHE B CE2 1 
ATOM 4970 C CZ  . PHE D 4 216 ? 349.904 337.112 475.661 1.00 78.91  ? 216 PHE B CZ  1 
ATOM 4971 N N   . ARG D 4 217 ? 356.399 340.630 475.339 1.00 67.11  ? 217 ARG B N   1 
ATOM 4972 C CA  . ARG D 4 217 ? 357.642 341.143 475.879 1.00 67.11  ? 217 ARG B CA  1 
ATOM 4973 C C   . ARG D 4 217 ? 358.237 342.259 475.043 1.00 67.11  ? 217 ARG B C   1 
ATOM 4974 O O   . ARG D 4 217 ? 359.432 342.518 475.170 1.00 67.11  ? 217 ARG B O   1 
ATOM 4975 C CB  . ARG D 4 217 ? 358.664 340.018 475.988 1.00 67.11  ? 217 ARG B CB  1 
ATOM 4976 C CG  . ARG D 4 217 ? 358.242 338.870 476.861 1.00 67.11  ? 217 ARG B CG  1 
ATOM 4977 C CD  . ARG D 4 217 ? 359.096 338.800 478.092 1.00 67.11  ? 217 ARG B CD  1 
ATOM 4978 N NE  . ARG D 4 217 ? 358.819 337.625 478.903 1.00 67.11  ? 217 ARG B NE  1 
ATOM 4979 C CZ  . ARG D 4 217 ? 359.738 336.754 479.291 1.00 67.11  ? 217 ARG B CZ  1 
ATOM 4980 N NH1 . ARG D 4 217 ? 359.397 335.719 480.033 1.00 67.11  ? 217 ARG B NH1 1 
ATOM 4981 N NH2 . ARG D 4 217 ? 360.996 336.917 478.941 1.00 67.11  ? 217 ARG B NH2 1 
ATOM 4982 N N   . HIS D 4 218 ? 357.467 342.908 474.181 1.00 63.63  ? 218 HIS B N   1 
ATOM 4983 C CA  . HIS D 4 218 ? 358.044 343.897 473.288 1.00 63.63  ? 218 HIS B CA  1 
ATOM 4984 C C   . HIS D 4 218 ? 357.023 344.964 472.942 1.00 63.63  ? 218 HIS B C   1 
ATOM 4985 O O   . HIS D 4 218 ? 355.935 344.656 472.454 1.00 63.63  ? 218 HIS B O   1 
ATOM 4986 C CB  . HIS D 4 218 ? 358.558 343.235 472.016 1.00 63.63  ? 218 HIS B CB  1 
ATOM 4987 C CG  . HIS D 4 218 ? 359.446 344.113 471.200 1.00 63.63  ? 218 HIS B CG  1 
ATOM 4988 N ND1 . HIS D 4 218 ? 359.768 343.834 469.893 1.00 63.63  ? 218 HIS B ND1 1 
ATOM 4989 C CD2 . HIS D 4 218 ? 360.066 345.275 471.500 1.00 63.63  ? 218 HIS B CD2 1 
ATOM 4990 C CE1 . HIS D 4 218 ? 360.555 344.784 469.424 1.00 63.63  ? 218 HIS B CE1 1 
ATOM 4991 N NE2 . HIS D 4 218 ? 360.750 345.672 470.380 1.00 63.63  ? 218 HIS B NE2 1 
ATOM 4992 N N   . ASN D 4 219 ? 357.393 346.221 473.173 1.00 62.53  ? 219 ASN B N   1 
ATOM 4993 C CA  . ASN D 4 219 ? 356.561 347.384 472.872 1.00 62.53  ? 219 ASN B CA  1 
ATOM 4994 C C   . ASN D 4 219 ? 357.296 348.156 471.790 1.00 62.53  ? 219 ASN B C   1 
ATOM 4995 O O   . ASN D 4 219 ? 358.145 348.994 472.093 1.00 62.53  ? 219 ASN B O   1 
ATOM 4996 C CB  . ASN D 4 219 ? 356.348 348.234 474.096 1.00 62.53  ? 219 ASN B CB  1 
ATOM 4997 C CG  . ASN D 4 219 ? 355.801 347.457 475.250 1.00 62.53  ? 219 ASN B CG  1 
ATOM 4998 O OD1 . ASN D 4 219 ? 354.799 346.760 475.124 1.00 62.53  ? 219 ASN B OD1 1 
ATOM 4999 N ND2 . ASN D 4 219 ? 356.460 347.562 476.392 1.00 62.53  ? 219 ASN B ND2 1 
ATOM 5000 N N   . ASN D 4 220 ? 356.965 347.890 470.535 1.00 61.87  ? 220 ASN B N   1 
ATOM 5001 C CA  . ASN D 4 220 ? 357.814 348.359 469.455 1.00 61.87  ? 220 ASN B CA  1 
ATOM 5002 C C   . ASN D 4 220 ? 357.499 349.769 468.981 1.00 61.87  ? 220 ASN B C   1 
ATOM 5003 O O   . ASN D 4 220 ? 358.263 350.303 468.175 1.00 61.87  ? 220 ASN B O   1 
ATOM 5004 C CB  . ASN D 4 220 ? 357.734 347.390 468.288 1.00 61.87  ? 220 ASN B CB  1 
ATOM 5005 C CG  . ASN D 4 220 ? 356.334 346.999 467.976 1.00 61.87  ? 220 ASN B CG  1 
ATOM 5006 O OD1 . ASN D 4 220 ? 355.399 347.477 468.606 1.00 61.87  ? 220 ASN B OD1 1 
ATOM 5007 N ND2 . ASN D 4 220 ? 356.167 346.127 466.999 1.00 61.87  ? 220 ASN B ND2 1 
ATOM 5008 N N   . LEU D 4 221 ? 356.410 350.385 469.430 1.00 60.07  ? 221 LEU B N   1 
ATOM 5009 C CA  . LEU D 4 221 ? 356.147 351.790 469.148 1.00 60.07  ? 221 LEU B CA  1 
ATOM 5010 C C   . LEU D 4 221 ? 355.817 352.529 470.432 1.00 60.07  ? 221 LEU B C   1 
ATOM 5011 O O   . LEU D 4 221 ? 355.362 351.947 471.414 1.00 60.07  ? 221 LEU B O   1 
ATOM 5012 C CB  . LEU D 4 221 ? 355.010 351.984 468.143 1.00 60.07  ? 221 LEU B CB  1 
ATOM 5013 C CG  . LEU D 4 221 ? 355.352 352.029 466.657 1.00 60.07  ? 221 LEU B CG  1 
ATOM 5014 C CD1 . LEU D 4 221 ? 355.725 350.681 466.087 1.00 60.07  ? 221 LEU B CD1 1 
ATOM 5015 C CD2 . LEU D 4 221 ? 354.179 352.575 465.911 1.00 60.07  ? 221 LEU B CD2 1 
ATOM 5016 N N   . THR D 4 222 ? 356.045 353.837 470.408 1.00 55.65  ? 222 THR B N   1 
ATOM 5017 C CA  . THR D 4 222 ? 355.748 354.695 471.549 1.00 55.65  ? 222 THR B CA  1 
ATOM 5018 C C   . THR D 4 222 ? 355.219 356.005 471.006 1.00 55.65  ? 222 THR B C   1 
ATOM 5019 O O   . THR D 4 222 ? 355.874 356.633 470.175 1.00 55.65  ? 222 THR B O   1 
ATOM 5020 C CB  . THR D 4 222 ? 356.983 354.929 472.396 1.00 55.65  ? 222 THR B CB  1 
ATOM 5021 O OG1 . THR D 4 222 ? 357.424 353.681 472.932 1.00 55.65  ? 222 THR B OG1 1 
ATOM 5022 C CG2 . THR D 4 222 ? 356.675 355.855 473.534 1.00 55.65  ? 222 THR B CG2 1 
ATOM 5023 N N   . LEU D 4 223 ? 354.043 356.408 471.451 1.00 53.93  ? 223 LEU B N   1 
ATOM 5024 C CA  . LEU D 4 223 ? 353.409 357.628 470.985 1.00 53.93  ? 223 LEU B CA  1 
ATOM 5025 C C   . LEU D 4 223 ? 353.577 358.705 472.044 1.00 53.93  ? 223 LEU B C   1 
ATOM 5026 O O   . LEU D 4 223 ? 353.052 358.569 473.147 1.00 53.93  ? 223 LEU B O   1 
ATOM 5027 C CB  . LEU D 4 223 ? 351.934 357.380 470.699 1.00 53.93  ? 223 LEU B CB  1 
ATOM 5028 C CG  . LEU D 4 223 ? 351.099 358.610 470.401 1.00 53.93  ? 223 LEU B CG  1 
ATOM 5029 C CD1 . LEU D 4 223 ? 351.363 359.080 469.003 1.00 53.93  ? 223 LEU B CD1 1 
ATOM 5030 C CD2 . LEU D 4 223 ? 349.656 358.268 470.572 1.00 53.93  ? 223 LEU B CD2 1 
ATOM 5031 N N   . MET D 4 224 ? 354.296 359.770 471.711 1.00 53.46  ? 224 MET B N   1 
ATOM 5032 C CA  . MET D 4 224 ? 354.589 360.849 472.640 1.00 53.46  ? 224 MET B CA  1 
ATOM 5033 C C   . MET D 4 224 ? 353.891 362.122 472.199 1.00 53.46  ? 224 MET B C   1 
ATOM 5034 O O   . MET D 4 224 ? 353.847 362.427 471.009 1.00 53.46  ? 224 MET B O   1 
ATOM 5035 C CB  . MET D 4 224 ? 356.083 361.109 472.718 1.00 53.46  ? 224 MET B CB  1 
ATOM 5036 C CG  . MET D 4 224 ? 356.901 359.982 473.265 1.00 53.46  ? 224 MET B CG  1 
ATOM 5037 S SD  . MET D 4 224 ? 358.622 360.458 473.281 1.00 53.46  ? 224 MET B SD  1 
ATOM 5038 C CE  . MET D 4 224 ? 359.339 359.067 474.114 1.00 53.46  ? 224 MET B CE  1 
ATOM 5039 N N   . ILE D 4 225 ? 353.355 362.871 473.157 1.00 52.60  ? 225 ILE B N   1 
ATOM 5040 C CA  . ILE D 4 225 ? 352.740 364.169 472.903 1.00 52.60  ? 225 ILE B CA  1 
ATOM 5041 C C   . ILE D 4 225 ? 353.355 365.169 473.868 1.00 52.60  ? 225 ILE B C   1 
ATOM 5042 O O   . ILE D 4 225 ? 353.143 365.070 475.079 1.00 52.60  ? 225 ILE B O   1 
ATOM 5043 C CB  . ILE D 4 225 ? 351.216 364.134 473.076 1.00 52.60  ? 225 ILE B CB  1 
ATOM 5044 C CG1 . ILE D 4 225 ? 350.576 363.199 472.066 1.00 52.60  ? 225 ILE B CG1 1 
ATOM 5045 C CG2 . ILE D 4 225 ? 350.652 365.491 472.868 1.00 52.60  ? 225 ILE B CG2 1 
ATOM 5046 C CD1 . ILE D 4 225 ? 349.103 363.078 472.229 1.00 52.60  ? 225 ILE B CD1 1 
ATOM 5047 N N   . ILE D 4 226 ? 354.119 366.127 473.342 1.00 50.48  ? 226 ILE B N   1 
ATOM 5048 C CA  . ILE D 4 226 ? 354.897 367.045 474.159 1.00 50.48  ? 226 ILE B CA  1 
ATOM 5049 C C   . ILE D 4 226 ? 354.523 368.482 473.826 1.00 50.48  ? 226 ILE B C   1 
ATOM 5050 O O   . ILE D 4 226 ? 354.670 368.904 472.678 1.00 50.48  ? 226 ILE B O   1 
ATOM 5051 C CB  . ILE D 4 226 ? 356.411 366.848 473.971 1.00 50.48  ? 226 ILE B CB  1 
ATOM 5052 C CG1 . ILE D 4 226 ? 356.799 365.397 474.193 1.00 50.48  ? 226 ILE B CG1 1 
ATOM 5053 C CG2 . ILE D 4 226 ? 357.171 367.712 474.932 1.00 50.48  ? 226 ILE B CG2 1 
ATOM 5054 C CD1 . ILE D 4 226 ? 358.193 365.107 473.809 1.00 50.48  ? 226 ILE B CD1 1 
ATOM 5055 N N   . PRO D 4 227 ? 354.069 369.278 474.782 1.00 51.30  ? 227 PRO B N   1 
ATOM 5056 C CA  . PRO D 4 227 ? 353.753 370.683 474.511 1.00 51.30  ? 227 PRO B CA  1 
ATOM 5057 C C   . PRO D 4 227 ? 355.014 371.528 474.494 1.00 51.30  ? 227 PRO B C   1 
ATOM 5058 O O   . PRO D 4 227 ? 355.635 371.762 475.535 1.00 51.30  ? 227 PRO B O   1 
ATOM 5059 C CB  . PRO D 4 227 ? 352.836 371.062 475.682 1.00 51.30  ? 227 PRO B CB  1 
ATOM 5060 C CG  . PRO D 4 227 ? 352.588 369.831 476.423 1.00 51.30  ? 227 PRO B CG  1 
ATOM 5061 C CD  . PRO D 4 227 ? 353.705 368.919 476.151 1.00 51.30  ? 227 PRO B CD  1 
ATOM 5062 N N   . PHE D 4 228 ? 355.388 372.006 473.311 1.00 51.77  ? 228 PHE B N   1 
ATOM 5063 C CA  . PHE D 4 228 ? 356.543 372.885 473.219 1.00 51.77  ? 228 PHE B CA  1 
ATOM 5064 C C   . PHE D 4 228 ? 356.199 374.281 473.708 1.00 51.77  ? 228 PHE B C   1 
ATOM 5065 O O   . PHE D 4 228 ? 356.801 374.780 474.660 1.00 51.77  ? 228 PHE B O   1 
ATOM 5066 C CB  . PHE D 4 228 ? 357.061 372.918 471.789 1.00 51.77  ? 228 PHE B CB  1 
ATOM 5067 C CG  . PHE D 4 228 ? 358.178 371.971 471.551 1.00 51.77  ? 228 PHE B CG  1 
ATOM 5068 C CD1 . PHE D 4 228 ? 359.473 372.335 471.826 1.00 51.77  ? 228 PHE B CD1 1 
ATOM 5069 C CD2 . PHE D 4 228 ? 357.931 370.701 471.087 1.00 51.77  ? 228 PHE B CD2 1 
ATOM 5070 C CE1 . PHE D 4 228 ? 360.496 371.463 471.622 1.00 51.77  ? 228 PHE B CE1 1 
ATOM 5071 C CE2 . PHE D 4 228 ? 358.958 369.826 470.888 1.00 51.77  ? 228 PHE B CE2 1 
ATOM 5072 C CZ  . PHE D 4 228 ? 360.239 370.210 471.155 1.00 51.77  ? 228 PHE B CZ  1 
ATOM 5073 N N   . VAL D 4 229 ? 355.224 374.921 473.078 1.00 50.88  ? 229 VAL B N   1 
ATOM 5074 C CA  . VAL D 4 229 ? 354.689 376.193 473.552 1.00 50.88  ? 229 VAL B CA  1 
ATOM 5075 C C   . VAL D 4 229 ? 353.536 375.880 474.498 1.00 50.88  ? 229 VAL B C   1 
ATOM 5076 O O   . VAL D 4 229 ? 352.590 375.198 474.088 1.00 50.88  ? 229 VAL B O   1 
ATOM 5077 C CB  . VAL D 4 229 ? 354.225 377.071 472.391 1.00 50.88  ? 229 VAL B CB  1 
ATOM 5078 C CG1 . VAL D 4 229 ? 353.586 378.319 472.911 1.00 50.88  ? 229 VAL B CG1 1 
ATOM 5079 C CG2 . VAL D 4 229 ? 355.395 377.416 471.537 1.00 50.88  ? 229 VAL B CG2 1 
ATOM 5080 N N   . PRO D 4 230 ? 353.577 376.334 475.744 1.00 51.24  ? 230 PRO B N   1 
ATOM 5081 C CA  . PRO D 4 230 ? 352.594 375.886 476.728 1.00 51.24  ? 230 PRO B CA  1 
ATOM 5082 C C   . PRO D 4 230 ? 351.228 376.500 476.481 1.00 51.24  ? 230 PRO B C   1 
ATOM 5083 O O   . PRO D 4 230 ? 351.062 377.425 475.691 1.00 51.24  ? 230 PRO B O   1 
ATOM 5084 C CB  . PRO D 4 230 ? 353.193 376.367 478.045 1.00 51.24  ? 230 PRO B CB  1 
ATOM 5085 C CG  . PRO D 4 230 ? 353.987 377.522 477.671 1.00 51.24  ? 230 PRO B CG  1 
ATOM 5086 C CD  . PRO D 4 230 ? 354.573 377.225 476.347 1.00 51.24  ? 230 PRO B CD  1 
ATOM 5087 N N   . LEU D 4 231 ? 350.230 375.948 477.158 1.00 52.14  ? 231 LEU B N   1 
ATOM 5088 C CA  . LEU D 4 231 ? 348.878 376.458 477.017 1.00 52.14  ? 231 LEU B CA  1 
ATOM 5089 C C   . LEU D 4 231 ? 348.751 377.785 477.733 1.00 52.14  ? 231 LEU B C   1 
ATOM 5090 O O   . LEU D 4 231 ? 349.286 377.972 478.825 1.00 52.14  ? 231 LEU B O   1 
ATOM 5091 C CB  . LEU D 4 231 ? 347.868 375.470 477.583 1.00 52.14  ? 231 LEU B CB  1 
ATOM 5092 C CG  . LEU D 4 231 ? 346.386 375.755 477.368 1.00 52.14  ? 231 LEU B CG  1 
ATOM 5093 C CD1 . LEU D 4 231 ? 345.976 375.443 475.968 1.00 52.14  ? 231 LEU B CD1 1 
ATOM 5094 C CD2 . LEU D 4 231 ? 345.578 374.947 478.309 1.00 52.14  ? 231 LEU B CD2 1 
ATOM 5095 N N   . ASN D 4 232 ? 348.049 378.719 477.107 1.00 54.61  ? 232 ASN B N   1 
ATOM 5096 C CA  . ASN D 4 232 ? 347.752 379.975 477.760 1.00 54.61  ? 232 ASN B CA  1 
ATOM 5097 C C   . ASN D 4 232 ? 346.341 380.383 477.403 1.00 54.61  ? 232 ASN B C   1 
ATOM 5098 O O   . ASN D 4 232 ? 345.826 380.030 476.345 1.00 54.61  ? 232 ASN B O   1 
ATOM 5099 C CB  . ASN D 4 232 ? 348.736 381.061 477.367 1.00 54.61  ? 232 ASN B CB  1 
ATOM 5100 C CG  . ASN D 4 232 ? 349.045 381.978 478.503 1.00 54.61  ? 232 ASN B CG  1 
ATOM 5101 O OD1 . ASN D 4 232 ? 348.580 381.767 479.620 1.00 54.61  ? 232 ASN B OD1 1 
ATOM 5102 N ND2 . ASN D 4 232 ? 349.844 383.001 478.241 1.00 54.61  ? 232 ASN B ND2 1 
ATOM 5103 N N   . TYR D 4 233 ? 345.718 381.119 478.309 1.00 58.55  ? 233 TYR B N   1 
ATOM 5104 C CA  . TYR D 4 233 ? 344.350 381.572 478.141 1.00 58.55  ? 233 TYR B CA  1 
ATOM 5105 C C   . TYR D 4 233 ? 344.169 382.793 479.024 1.00 58.55  ? 233 TYR B C   1 
ATOM 5106 O O   . TYR D 4 233 ? 344.941 383.027 479.953 1.00 58.55  ? 233 TYR B O   1 
ATOM 5107 C CB  . TYR D 4 233 ? 343.345 380.472 478.494 1.00 58.55  ? 233 TYR B CB  1 
ATOM 5108 C CG  . TYR D 4 233 ? 343.608 379.796 479.811 1.00 58.55  ? 233 TYR B CG  1 
ATOM 5109 C CD1 . TYR D 4 233 ? 343.128 380.329 480.993 1.00 58.55  ? 233 TYR B CD1 1 
ATOM 5110 C CD2 . TYR D 4 233 ? 344.328 378.622 479.874 1.00 58.55  ? 233 TYR B CD2 1 
ATOM 5111 C CE1 . TYR D 4 233 ? 343.374 379.730 482.193 1.00 58.55  ? 233 TYR B CE1 1 
ATOM 5112 C CE2 . TYR D 4 233 ? 344.581 378.010 481.074 1.00 58.55  ? 233 TYR B CE2 1 
ATOM 5113 C CZ  . TYR D 4 233 ? 344.098 378.571 482.228 1.00 58.55  ? 233 TYR B CZ  1 
ATOM 5114 O OH  . TYR D 4 233 ? 344.328 377.969 483.435 1.00 58.55  ? 233 TYR B OH  1 
ATOM 5115 N N   . SER D 4 234 ? 343.137 383.564 478.733 1.00 62.28  ? 234 SER B N   1 
ATOM 5116 C CA  . SER D 4 234 ? 342.802 384.677 479.597 1.00 62.28  ? 234 SER B CA  1 
ATOM 5117 C C   . SER D 4 234 ? 341.876 384.199 480.702 1.00 62.28  ? 234 SER B C   1 
ATOM 5118 O O   . SER D 4 234 ? 341.392 383.069 480.693 1.00 62.28  ? 234 SER B O   1 
ATOM 5119 C CB  . SER D 4 234 ? 342.161 385.789 478.791 1.00 62.28  ? 234 SER B CB  1 
ATOM 5120 O OG  . SER D 4 234 ? 341.232 385.223 477.900 1.00 62.28  ? 234 SER B OG  1 
ATOM 5121 N N   . GLU D 4 235 ? 341.629 385.066 481.669 1.00 64.34  ? 235 GLU B N   1 
ATOM 5122 C CA  . GLU D 4 235 ? 340.745 384.743 482.776 1.00 64.34  ? 235 GLU B CA  1 
ATOM 5123 C C   . GLU D 4 235 ? 339.314 384.683 482.265 1.00 64.34  ? 235 GLU B C   1 
ATOM 5124 O O   . GLU D 4 235 ? 338.852 385.605 481.589 1.00 64.34  ? 235 GLU B O   1 
ATOM 5125 C CB  . GLU D 4 235 ? 340.901 385.783 483.880 1.00 64.34  ? 235 GLU B CB  1 
ATOM 5126 C CG  . GLU D 4 235 ? 339.763 385.859 484.867 1.00 64.34  ? 235 GLU B CG  1 
ATOM 5127 C CD  . GLU D 4 235 ? 339.530 384.557 485.581 1.00 64.34  ? 235 GLU B CD  1 
ATOM 5128 O OE1 . GLU D 4 235 ? 338.423 384.000 485.444 1.00 64.34  ? 235 GLU B OE1 1 
ATOM 5129 O OE2 . GLU D 4 235 ? 340.456 384.084 486.268 1.00 64.34  ? 235 GLU B OE2 1 
ATOM 5130 N N   . GLY D 4 236 ? 338.619 383.586 482.565 1.00 60.33  ? 236 GLY B N   1 
ATOM 5131 C CA  . GLY D 4 236 ? 337.262 383.354 482.106 1.00 60.33  ? 236 GLY B CA  1 
ATOM 5132 C C   . GLY D 4 236 ? 337.128 382.137 481.215 1.00 60.33  ? 236 GLY B C   1 
ATOM 5133 O O   . GLY D 4 236 ? 336.113 381.440 481.279 1.00 60.33  ? 236 GLY B O   1 
ATOM 5134 N N   . SER D 4 237 ? 338.137 381.866 480.391 1.00 60.22  ? 237 SER B N   1 
ATOM 5135 C CA  . SER D 4 237 ? 338.094 380.729 479.488 1.00 60.22  ? 237 SER B CA  1 
ATOM 5136 C C   . SER D 4 237 ? 338.281 379.431 480.261 1.00 60.22  ? 237 SER B C   1 
ATOM 5137 O O   . SER D 4 237 ? 338.624 379.425 481.443 1.00 60.22  ? 237 SER B O   1 
ATOM 5138 C CB  . SER D 4 237 ? 339.165 380.854 478.410 1.00 60.22  ? 237 SER B CB  1 
ATOM 5139 O OG  . SER D 4 237 ? 339.182 382.147 477.847 1.00 60.22  ? 237 SER B OG  1 
ATOM 5140 N N   . SER D 4 238 ? 338.056 378.323 479.574 1.00 58.77  ? 238 SER B N   1 
ATOM 5141 C CA  . SER D 4 238 ? 338.097 377.020 480.221 1.00 58.77  ? 238 SER B CA  1 
ATOM 5142 C C   . SER D 4 238 ? 339.534 376.648 480.554 1.00 58.77  ? 238 SER B C   1 
ATOM 5143 O O   . SER D 4 238 ? 340.368 376.569 479.652 1.00 58.77  ? 238 SER B O   1 
ATOM 5144 C CB  . SER D 4 238 ? 337.476 375.971 479.318 1.00 58.77  ? 238 SER B CB  1 
ATOM 5145 O OG  . SER D 4 238 ? 336.264 376.447 478.768 1.00 58.77  ? 238 SER B OG  1 
ATOM 5146 N N   . PRO D 4 239 ? 339.851 376.384 481.812 1.00 59.40  ? 239 PRO B N   1 
ATOM 5147 C CA  . PRO D 4 239 ? 341.253 376.374 482.236 1.00 59.40  ? 239 PRO B CA  1 
ATOM 5148 C C   . PRO D 4 239 ? 342.072 375.165 481.818 1.00 59.40  ? 239 PRO B C   1 
ATOM 5149 O O   . PRO D 4 239 ? 343.254 375.100 482.159 1.00 59.40  ? 239 PRO B O   1 
ATOM 5150 C CB  . PRO D 4 239 ? 341.139 376.449 483.759 1.00 59.40  ? 239 PRO B CB  1 
ATOM 5151 C CG  . PRO D 4 239 ? 339.864 375.825 484.051 1.00 59.40  ? 239 PRO B CG  1 
ATOM 5152 C CD  . PRO D 4 239 ? 338.942 376.191 482.947 1.00 59.40  ? 239 PRO B CD  1 
ATOM 5153 N N   . TYR D 4 240 ? 341.488 374.214 481.092 1.00 61.94  ? 240 TYR B N   1 
ATOM 5154 C CA  . TYR D 4 240 ? 342.251 373.101 480.547 1.00 61.94  ? 240 TYR B CA  1 
ATOM 5155 C C   . TYR D 4 240 ? 341.533 372.531 479.337 1.00 61.94  ? 240 TYR B C   1 
ATOM 5156 O O   . TYR D 4 240 ? 340.313 372.616 479.225 1.00 61.94  ? 240 TYR B O   1 
ATOM 5157 C CB  . TYR D 4 240 ? 342.500 371.998 481.579 1.00 61.94  ? 240 TYR B CB  1 
ATOM 5158 C CG  . TYR D 4 240 ? 341.282 371.488 482.292 1.00 61.94  ? 240 TYR B CG  1 
ATOM 5159 C CD1 . TYR D 4 240 ? 340.505 370.476 481.747 1.00 61.94  ? 240 TYR B CD1 1 
ATOM 5160 C CD2 . TYR D 4 240 ? 340.924 371.999 483.526 1.00 61.94  ? 240 TYR B CD2 1 
ATOM 5161 C CE1 . TYR D 4 240 ? 339.393 370.003 482.399 1.00 61.94  ? 240 TYR B CE1 1 
ATOM 5162 C CE2 . TYR D 4 240 ? 339.814 371.531 484.193 1.00 61.94  ? 240 TYR B CE2 1 
ATOM 5163 C CZ  . TYR D 4 240 ? 339.050 370.532 483.623 1.00 61.94  ? 240 TYR B CZ  1 
ATOM 5164 O OH  . TYR D 4 240 ? 337.939 370.057 484.280 1.00 61.94  ? 240 TYR B OH  1 
ATOM 5165 N N   . VAL D 4 241 ? 342.304 371.906 478.459 1.00 55.49  ? 241 VAL B N   1 
ATOM 5166 C CA  . VAL D 4 241 ? 341.837 371.473 477.150 1.00 55.49  ? 241 VAL B CA  1 
ATOM 5167 C C   . VAL D 4 241 ? 342.013 369.965 477.036 1.00 55.49  ? 241 VAL B C   1 
ATOM 5168 O O   . VAL D 4 241 ? 343.089 369.453 477.356 1.00 55.49  ? 241 VAL B O   1 
ATOM 5169 C CB  . VAL D 4 241 ? 342.605 372.216 476.053 1.00 55.49  ? 241 VAL B CB  1 
ATOM 5170 C CG1 . VAL D 4 241 ? 342.452 371.546 474.725 1.00 55.49  ? 241 VAL B CG1 1 
ATOM 5171 C CG2 . VAL D 4 241 ? 342.133 373.623 475.987 1.00 55.49  ? 241 VAL B CG2 1 
ATOM 5172 N N   . PRO D 4 242 ? 341.003 369.212 476.620 1.00 55.56  ? 242 PRO B N   1 
ATOM 5173 C CA  . PRO D 4 242 ? 341.169 367.767 476.493 1.00 55.56  ? 242 PRO B CA  1 
ATOM 5174 C C   . PRO D 4 242 ? 341.800 367.367 475.174 1.00 55.56  ? 242 PRO B C   1 
ATOM 5175 O O   . PRO D 4 242 ? 341.611 368.014 474.147 1.00 55.56  ? 242 PRO B O   1 
ATOM 5176 C CB  . PRO D 4 242 ? 339.733 367.250 476.586 1.00 55.56  ? 242 PRO B CB  1 
ATOM 5177 C CG  . PRO D 4 242 ? 338.926 368.347 476.086 1.00 55.56  ? 242 PRO B CG  1 
ATOM 5178 C CD  . PRO D 4 242 ? 339.596 369.609 476.494 1.00 55.56  ? 242 PRO B CD  1 
ATOM 5179 N N   . ILE D 4 243 ? 342.566 366.278 475.219 1.00 54.55  ? 243 ILE B N   1 
ATOM 5180 C CA  . ILE D 4 243 ? 343.188 365.674 474.045 1.00 54.55  ? 243 ILE B CA  1 
ATOM 5181 C C   . ILE D 4 243 ? 342.670 364.251 473.916 1.00 54.55  ? 243 ILE B C   1 
ATOM 5182 O O   . ILE D 4 243 ? 342.633 363.510 474.900 1.00 54.55  ? 243 ILE B O   1 
ATOM 5183 C CB  . ILE D 4 243 ? 344.724 365.681 474.148 1.00 54.55  ? 243 ILE B CB  1 
ATOM 5184 C CG1 . ILE D 4 243 ? 345.238 367.064 474.506 1.00 54.55  ? 243 ILE B CG1 1 
ATOM 5185 C CG2 . ILE D 4 243 ? 345.354 365.242 472.853 1.00 54.55  ? 243 ILE B CG2 1 
ATOM 5186 C CD1 . ILE D 4 243 ? 346.700 367.104 474.720 1.00 54.55  ? 243 ILE B CD1 1 
ATOM 5187 N N   . THR D 4 244 ? 342.277 363.861 472.708 1.00 58.98  ? 244 THR B N   1 
ATOM 5188 C CA  . THR D 4 244 ? 341.628 362.575 472.486 1.00 58.98  ? 244 THR B CA  1 
ATOM 5189 C C   . THR D 4 244 ? 342.411 361.774 471.462 1.00 58.98  ? 244 THR B C   1 
ATOM 5190 O O   . THR D 4 244 ? 342.584 362.220 470.327 1.00 58.98  ? 244 THR B O   1 
ATOM 5191 C CB  . THR D 4 244 ? 340.185 362.769 472.026 1.00 58.98  ? 244 THR B CB  1 
ATOM 5192 O OG1 . THR D 4 244 ? 339.417 363.313 473.101 1.00 58.98  ? 244 THR B OG1 1 
ATOM 5193 C CG2 . THR D 4 244 ? 339.574 361.459 471.620 1.00 58.98  ? 244 THR B CG2 1 
ATOM 5194 N N   . VAL D 4 245 ? 342.866 360.589 471.855 1.00 62.16  ? 245 VAL B N   1 
ATOM 5195 C CA  . VAL D 4 245 ? 343.671 359.717 471.010 1.00 62.16  ? 245 VAL B CA  1 
ATOM 5196 C C   . VAL D 4 245 ? 342.807 358.548 470.574 1.00 62.16  ? 245 VAL B C   1 
ATOM 5197 O O   . VAL D 4 245 ? 342.080 357.972 471.388 1.00 62.16  ? 245 VAL B O   1 
ATOM 5198 C CB  . VAL D 4 245 ? 344.921 359.220 471.752 1.00 62.16  ? 245 VAL B CB  1 
ATOM 5199 C CG1 . VAL D 4 245 ? 345.885 358.584 470.797 1.00 62.16  ? 245 VAL B CG1 1 
ATOM 5200 C CG2 . VAL D 4 245 ? 345.580 360.357 472.465 1.00 62.16  ? 245 VAL B CG2 1 
ATOM 5201 N N   . THR D 4 246 ? 342.887 358.197 469.296 1.00 65.34  ? 246 THR B N   1 
ATOM 5202 C CA  . THR D 4 246 ? 342.132 357.091 468.729 1.00 65.34  ? 246 THR B CA  1 
ATOM 5203 C C   . THR D 4 246 ? 343.081 356.242 467.904 1.00 65.34  ? 246 THR B C   1 
ATOM 5204 O O   . THR D 4 246 ? 343.723 356.752 466.985 1.00 65.34  ? 246 THR B O   1 
ATOM 5205 C CB  . THR D 4 246 ? 340.982 357.604 467.867 1.00 65.34  ? 246 THR B CB  1 
ATOM 5206 O OG1 . THR D 4 246 ? 339.997 358.208 468.703 1.00 65.34  ? 246 THR B OG1 1 
ATOM 5207 C CG2 . THR D 4 246 ? 340.340 356.490 467.118 1.00 65.34  ? 246 THR B CG2 1 
ATOM 5208 N N   . ILE D 4 247 ? 343.174 354.958 468.225 1.00 68.32  ? 247 ILE B N   1 
ATOM 5209 C CA  . ILE D 4 247 ? 344.056 354.034 467.527 1.00 68.32  ? 247 ILE B CA  1 
ATOM 5210 C C   . ILE D 4 247 ? 343.214 353.001 466.800 1.00 68.32  ? 247 ILE B C   1 
ATOM 5211 O O   . ILE D 4 247 ? 342.248 352.475 467.356 1.00 68.32  ? 247 ILE B O   1 
ATOM 5212 C CB  . ILE D 4 247 ? 345.027 353.352 468.503 1.00 68.32  ? 247 ILE B CB  1 
ATOM 5213 C CG1 . ILE D 4 247 ? 345.610 354.380 469.451 1.00 68.32  ? 247 ILE B CG1 1 
ATOM 5214 C CG2 . ILE D 4 247 ? 346.154 352.693 467.758 1.00 68.32  ? 247 ILE B CG2 1 
ATOM 5215 C CD1 . ILE D 4 247 ? 346.149 353.788 470.698 1.00 68.32  ? 247 ILE B CD1 1 
ATOM 5216 N N   . ALA D 4 248 ? 343.580 352.710 465.565 1.00 72.93  ? 248 ALA B N   1 
ATOM 5217 C CA  . ALA D 4 248 ? 342.912 351.687 464.780 1.00 72.93  ? 248 ALA B CA  1 
ATOM 5218 C C   . ALA D 4 248 ? 343.937 350.749 464.166 1.00 72.93  ? 248 ALA B C   1 
ATOM 5219 O O   . ALA D 4 248 ? 344.750 351.186 463.349 1.00 72.93  ? 248 ALA B O   1 
ATOM 5220 C CB  . ALA D 4 248 ? 342.073 352.320 463.680 1.00 72.93  ? 248 ALA B CB  1 
ATOM 5221 N N   . PRO D 4 249 ? 343.935 349.469 464.529 1.00 77.36  ? 249 PRO B N   1 
ATOM 5222 C CA  . PRO D 4 249 ? 344.936 348.549 463.987 1.00 77.36  ? 249 PRO B CA  1 
ATOM 5223 C C   . PRO D 4 249 ? 344.690 348.249 462.525 1.00 77.36  ? 249 PRO B C   1 
ATOM 5224 O O   . PRO D 4 249 ? 343.559 348.010 462.108 1.00 77.36  ? 249 PRO B O   1 
ATOM 5225 C CB  . PRO D 4 249 ? 344.756 347.292 464.837 1.00 77.36  ? 249 PRO B CB  1 
ATOM 5226 C CG  . PRO D 4 249 ? 344.031 347.741 466.032 1.00 77.36  ? 249 PRO B CG  1 
ATOM 5227 C CD  . PRO D 4 249 ? 343.157 348.846 465.604 1.00 77.36  ? 249 PRO B CD  1 
ATOM 5228 N N   . MET D 4 250 ? 345.764 348.268 461.746 1.00 88.21  ? 250 MET B N   1 
ATOM 5229 C CA  . MET D 4 250 ? 345.719 347.920 460.335 1.00 88.21  ? 250 MET B CA  1 
ATOM 5230 C C   . MET D 4 250 ? 346.594 346.698 460.121 1.00 88.21  ? 250 MET B C   1 
ATOM 5231 O O   . MET D 4 250 ? 347.683 346.617 460.693 1.00 88.21  ? 250 MET B O   1 
ATOM 5232 C CB  . MET D 4 250 ? 346.197 349.075 459.461 1.00 88.21  ? 250 MET B CB  1 
ATOM 5233 C CG  . MET D 4 250 ? 345.180 350.175 459.282 1.00 88.21  ? 250 MET B CG  1 
ATOM 5234 S SD  . MET D 4 250 ? 343.597 349.578 458.654 1.00 88.21  ? 250 MET B SD  1 
ATOM 5235 C CE  . MET D 4 250 ? 342.548 351.011 458.897 1.00 88.21  ? 250 MET B CE  1 
ATOM 5236 N N   . CYS D 4 251 ? 346.088 345.741 459.338 1.00 99.37  ? 251 CYS B N   1 
ATOM 5237 C CA  . CYS D 4 251 ? 346.795 344.533 458.887 1.00 99.37  ? 251 CYS B CA  1 
ATOM 5238 C C   . CYS D 4 251 ? 347.357 343.693 460.046 1.00 99.37  ? 251 CYS B C   1 
ATOM 5239 O O   . CYS D 4 251 ? 348.503 343.247 460.041 1.00 99.37  ? 251 CYS B O   1 
ATOM 5240 C CB  . CYS D 4 251 ? 347.861 344.890 457.833 1.00 99.37  ? 251 CYS B CB  1 
ATOM 5241 S SG  . CYS D 4 251 ? 349.473 345.635 458.286 1.00 99.37  ? 251 CYS B SG  1 
ATOM 5242 N N   . ALA D 4 252 ? 346.494 343.420 461.021 1.00 103.35 ? 252 ALA B N   1 
ATOM 5243 C CA  . ALA D 4 252 ? 346.839 342.557 462.144 1.00 103.35 ? 252 ALA B CA  1 
ATOM 5244 C C   . ALA D 4 252 ? 346.674 341.091 461.770 1.00 103.35 ? 252 ALA B C   1 
ATOM 5245 O O   . ALA D 4 252 ? 345.685 340.708 461.139 1.00 103.35 ? 252 ALA B O   1 
ATOM 5246 C CB  . ALA D 4 252 ? 345.962 342.869 463.355 1.00 103.35 ? 252 ALA B CB  1 
ATOM 5247 N N   . GLU D 4 253 ? 347.638 340.270 462.175 1.00 106.13 ? 253 GLU B N   1 
ATOM 5248 C CA  . GLU D 4 253 ? 347.541 338.829 461.982 1.00 106.13 ? 253 GLU B CA  1 
ATOM 5249 C C   . GLU D 4 253 ? 348.444 338.148 462.990 1.00 106.13 ? 253 GLU B C   1 
ATOM 5250 O O   . GLU D 4 253 ? 349.440 338.735 463.411 1.00 106.13 ? 253 GLU B O   1 
ATOM 5251 C CB  . GLU D 4 253 ? 347.945 338.412 460.573 1.00 106.13 ? 253 GLU B CB  1 
ATOM 5252 C CG  . GLU D 4 253 ? 349.195 339.062 460.083 1.00 106.13 ? 253 GLU B CG  1 
ATOM 5253 C CD  . GLU D 4 253 ? 349.493 338.681 458.665 1.00 106.13 ? 253 GLU B CD  1 
ATOM 5254 O OE1 . GLU D 4 253 ? 349.236 339.498 457.765 1.00 106.13 ? 253 GLU B OE1 1 
ATOM 5255 O OE2 . GLU D 4 253 ? 349.969 337.552 458.447 1.00 106.13 ? 253 GLU B OE2 1 
ATOM 5256 N N   . TYR D 4 254 ? 348.089 336.927 463.388 1.00 111.81 ? 254 TYR B N   1 
ATOM 5257 C CA  . TYR D 4 254 ? 348.794 336.200 464.434 1.00 111.81 ? 254 TYR B CA  1 
ATOM 5258 C C   . TYR D 4 254 ? 349.181 334.807 463.943 1.00 111.81 ? 254 TYR B C   1 
ATOM 5259 O O   . TYR D 4 254 ? 348.807 334.386 462.847 1.00 111.81 ? 254 TYR B O   1 
ATOM 5260 C CB  . TYR D 4 254 ? 347.933 336.141 465.696 1.00 111.81 ? 254 TYR B CB  1 
ATOM 5261 C CG  . TYR D 4 254 ? 347.157 337.406 465.928 1.00 111.81 ? 254 TYR B CG  1 
ATOM 5262 C CD1 . TYR D 4 254 ? 347.805 338.581 466.249 1.00 111.81 ? 254 TYR B CD1 1 
ATOM 5263 C CD2 . TYR D 4 254 ? 345.778 337.432 465.785 1.00 111.81 ? 254 TYR B CD2 1 
ATOM 5264 C CE1 . TYR D 4 254 ? 347.109 339.740 466.431 1.00 111.81 ? 254 TYR B CE1 1 
ATOM 5265 C CE2 . TYR D 4 254 ? 345.071 338.586 465.976 1.00 111.81 ? 254 TYR B CE2 1 
ATOM 5266 C CZ  . TYR D 4 254 ? 345.742 339.737 466.298 1.00 111.81 ? 254 TYR B CZ  1 
ATOM 5267 O OH  . TYR D 4 254 ? 345.044 340.902 466.490 1.00 111.81 ? 254 TYR B OH  1 
ATOM 5268 N N   . ASN D 4 255 ? 349.924 334.081 464.778 1.00 120.46 ? 255 ASN B N   1 
ATOM 5269 C CA  . ASN D 4 255 ? 350.499 332.786 464.414 1.00 120.46 ? 255 ASN B CA  1 
ATOM 5270 C C   . ASN D 4 255 ? 349.963 331.735 465.374 1.00 120.46 ? 255 ASN B C   1 
ATOM 5271 O O   . ASN D 4 255 ? 350.205 331.815 466.581 1.00 120.46 ? 255 ASN B O   1 
ATOM 5272 C CB  . ASN D 4 255 ? 352.025 332.834 464.471 1.00 120.46 ? 255 ASN B CB  1 
ATOM 5273 C CG  . ASN D 4 255 ? 352.683 331.785 463.602 1.00 120.46 ? 255 ASN B CG  1 
ATOM 5274 O OD1 . ASN D 4 255 ? 352.546 331.799 462.381 1.00 120.46 ? 255 ASN B OD1 1 
ATOM 5275 N ND2 . ASN D 4 255 ? 353.426 330.882 464.228 1.00 120.46 ? 255 ASN B ND2 1 
ATOM 5276 N N   . GLY D 4 256 ? 349.242 330.758 464.844 1.00 127.64 ? 256 GLY B N   1 
ATOM 5277 C CA  . GLY D 4 256 ? 348.740 329.683 465.673 1.00 127.64 ? 256 GLY B CA  1 
ATOM 5278 C C   . GLY D 4 256 ? 347.659 328.909 464.960 1.00 127.64 ? 256 GLY B C   1 
ATOM 5279 O O   . GLY D 4 256 ? 347.178 329.294 463.892 1.00 127.64 ? 256 GLY B O   1 
ATOM 5280 N N   . LEU D 4 257 ? 347.279 327.799 465.584 1.00 132.09 ? 257 LEU B N   1 
ATOM 5281 C CA  . LEU D 4 257 ? 346.235 326.925 465.064 1.00 132.09 ? 257 LEU B CA  1 
ATOM 5282 C C   . LEU D 4 257 ? 345.480 326.259 466.208 1.00 132.09 ? 257 LEU B C   1 
ATOM 5283 O O   . LEU D 4 257 ? 344.387 325.730 466.018 1.00 132.09 ? 257 LEU B O   1 
ATOM 5284 C CB  . LEU D 4 257 ? 346.829 325.862 464.136 1.00 132.09 ? 257 LEU B CB  1 
ATOM 5285 C CG  . LEU D 4 257 ? 346.941 326.187 462.646 1.00 132.09 ? 257 LEU B CG  1 
ATOM 5286 C CD1 . LEU D 4 257 ? 347.273 324.930 461.855 1.00 132.09 ? 257 LEU B CD1 1 
ATOM 5287 C CD2 . LEU D 4 257 ? 345.664 326.833 462.128 1.00 132.09 ? 257 LEU B CD2 1 
ATOM 5288 N N   . GLY E 5 1   ? 409.399 327.110 441.349 1.00 63.41  ? 1   GLY C N   1 
ATOM 5289 C CA  . GLY E 5 1   ? 408.015 327.453 441.090 1.00 63.41  ? 1   GLY C CA  1 
ATOM 5290 C C   . GLY E 5 1   ? 407.898 328.705 440.251 1.00 63.41  ? 1   GLY C C   1 
ATOM 5291 O O   . GLY E 5 1   ? 408.783 329.005 439.461 1.00 63.41  ? 1   GLY C O   1 
ATOM 5292 N N   . LEU E 5 2   ? 406.809 329.431 440.409 1.00 61.91  ? 2   LEU C N   1 
ATOM 5293 C CA  . LEU E 5 2   ? 406.672 330.706 439.733 1.00 61.91  ? 2   LEU C CA  1 
ATOM 5294 C C   . LEU E 5 2   ? 407.507 331.737 440.471 1.00 61.91  ? 2   LEU C C   1 
ATOM 5295 O O   . LEU E 5 2   ? 407.343 331.889 441.684 1.00 61.91  ? 2   LEU C O   1 
ATOM 5296 C CB  . LEU E 5 2   ? 405.221 331.137 439.697 1.00 61.91  ? 2   LEU C CB  1 
ATOM 5297 C CG  . LEU E 5 2   ? 404.943 332.307 438.766 1.00 61.91  ? 2   LEU C CG  1 
ATOM 5298 C CD1 . LEU E 5 2   ? 404.591 331.787 437.397 1.00 61.91  ? 2   LEU C CD1 1 
ATOM 5299 C CD2 . LEU E 5 2   ? 403.845 333.186 439.307 1.00 61.91  ? 2   LEU C CD2 1 
ATOM 5300 N N   . PRO E 5 3   ? 408.413 332.451 439.803 1.00 61.31  ? 3   PRO C N   1 
ATOM 5301 C CA  . PRO E 5 3   ? 409.296 333.392 440.504 1.00 61.31  ? 3   PRO C CA  1 
ATOM 5302 C C   . PRO E 5 3   ? 408.557 334.663 440.890 1.00 61.31  ? 3   PRO C C   1 
ATOM 5303 O O   . PRO E 5 3   ? 408.066 335.387 440.024 1.00 61.31  ? 3   PRO C O   1 
ATOM 5304 C CB  . PRO E 5 3   ? 410.390 333.676 439.473 1.00 61.31  ? 3   PRO C CB  1 
ATOM 5305 C CG  . PRO E 5 3   ? 410.252 332.616 438.458 1.00 61.31  ? 3   PRO C CG  1 
ATOM 5306 C CD  . PRO E 5 3   ? 408.819 332.275 438.409 1.00 61.31  ? 3   PRO C CD  1 
ATOM 5307 N N   . VAL E 5 4   ? 408.488 334.941 442.191 1.00 60.24  ? 4   VAL C N   1 
ATOM 5308 C CA  . VAL E 5 4   ? 407.874 336.169 442.683 1.00 60.24  ? 4   VAL C CA  1 
ATOM 5309 C C   . VAL E 5 4   ? 408.906 336.990 443.437 1.00 60.24  ? 4   VAL C C   1 
ATOM 5310 O O   . VAL E 5 4   ? 410.028 336.537 443.665 1.00 60.24  ? 4   VAL C O   1 
ATOM 5311 C CB  . VAL E 5 4   ? 406.663 335.877 443.579 1.00 60.24  ? 4   VAL C CB  1 
ATOM 5312 C CG1 . VAL E 5 4   ? 405.639 335.073 442.833 1.00 60.24  ? 4   VAL C CG1 1 
ATOM 5313 C CG2 . VAL E 5 4   ? 407.099 335.157 444.818 1.00 60.24  ? 4   VAL C CG2 1 
ATOM 5314 N N   . MET E 5 5   ? 408.524 338.193 443.850 1.00 59.73  ? 5   MET C N   1 
ATOM 5315 C CA  . MET E 5 5   ? 409.472 339.167 444.378 1.00 59.73  ? 5   MET C CA  1 
ATOM 5316 C C   . MET E 5 5   ? 408.682 340.137 445.239 1.00 59.73  ? 5   MET C C   1 
ATOM 5317 O O   . MET E 5 5   ? 407.893 340.914 444.704 1.00 59.73  ? 5   MET C O   1 
ATOM 5318 C CB  . MET E 5 5   ? 410.164 339.886 443.232 1.00 59.73  ? 5   MET C CB  1 
ATOM 5319 C CG  . MET E 5 5   ? 411.185 340.926 443.613 1.00 59.73  ? 5   MET C CG  1 
ATOM 5320 S SD  . MET E 5 5   ? 411.604 342.010 442.241 1.00 59.73  ? 5   MET C SD  1 
ATOM 5321 C CE  . MET E 5 5   ? 411.636 340.863 440.865 1.00 59.73  ? 5   MET C CE  1 
ATOM 5322 N N   . THR E 5 6   ? 408.886 340.100 446.553 1.00 52.89  ? 6   THR C N   1 
ATOM 5323 C CA  . THR E 5 6   ? 408.066 340.886 447.465 1.00 52.89  ? 6   THR C CA  1 
ATOM 5324 C C   . THR E 5 6   ? 408.607 342.299 447.616 1.00 52.89  ? 6   THR C C   1 
ATOM 5325 O O   . THR E 5 6   ? 409.804 342.497 447.822 1.00 52.89  ? 6   THR C O   1 
ATOM 5326 C CB  . THR E 5 6   ? 407.994 340.222 448.830 1.00 52.89  ? 6   THR C CB  1 
ATOM 5327 O OG1 . THR E 5 6   ? 409.200 340.489 449.542 1.00 52.89  ? 6   THR C OG1 1 
ATOM 5328 C CG2 . THR E 5 6   ? 407.838 338.743 448.679 1.00 52.89  ? 6   THR C CG2 1 
ATOM 5329 N N   . THR E 5 7   ? 407.711 343.273 447.545 1.00 50.48  ? 7   THR C N   1 
ATOM 5330 C CA  . THR E 5 7   ? 408.049 344.686 447.536 1.00 50.48  ? 7   THR C CA  1 
ATOM 5331 C C   . THR E 5 7   ? 407.991 345.247 448.952 1.00 50.48  ? 7   THR C C   1 
ATOM 5332 O O   . THR E 5 7   ? 407.536 344.569 449.868 1.00 50.48  ? 7   THR C O   1 
ATOM 5333 C CB  . THR E 5 7   ? 407.084 345.407 446.604 1.00 50.48  ? 7   THR C CB  1 
ATOM 5334 O OG1 . THR E 5 7   ? 405.750 345.029 446.933 1.00 50.48  ? 7   THR C OG1 1 
ATOM 5335 C CG2 . THR E 5 7   ? 407.361 345.018 445.186 1.00 50.48  ? 7   THR C CG2 1 
ATOM 5336 N N   . PRO E 5 8   ? 408.499 346.463 449.183 1.00 48.58  ? 8   PRO C N   1 
ATOM 5337 C CA  . PRO E 5 8   ? 408.309 347.090 450.490 1.00 48.58  ? 8   PRO C CA  1 
ATOM 5338 C C   . PRO E 5 8   ? 406.856 347.399 450.787 1.00 48.58  ? 8   PRO C C   1 
ATOM 5339 O O   . PRO E 5 8   ? 406.036 347.600 449.893 1.00 48.58  ? 8   PRO C O   1 
ATOM 5340 C CB  . PRO E 5 8   ? 409.133 348.376 450.391 1.00 48.58  ? 8   PRO C CB  1 
ATOM 5341 C CG  . PRO E 5 8   ? 409.492 348.509 449.000 1.00 48.58  ? 8   PRO C CG  1 
ATOM 5342 C CD  . PRO E 5 8   ? 409.590 347.141 448.473 1.00 48.58  ? 8   PRO C CD  1 
ATOM 5343 N N   . GLY E 5 9   ? 406.547 347.432 452.075 1.00 52.08  ? 9   GLY C N   1 
ATOM 5344 C CA  . GLY E 5 9   ? 405.173 347.498 452.508 1.00 52.08  ? 9   GLY C CA  1 
ATOM 5345 C C   . GLY E 5 9   ? 404.410 346.226 452.245 1.00 52.08  ? 9   GLY C C   1 
ATOM 5346 O O   . GLY E 5 9   ? 403.305 346.275 451.700 1.00 52.08  ? 9   GLY C O   1 
ATOM 5347 N N   . SER E 5 10  ? 404.986 345.071 452.574 1.00 51.41  ? 10  SER C N   1 
ATOM 5348 C CA  . SER E 5 10  ? 404.319 343.806 452.309 1.00 51.41  ? 10  SER C CA  1 
ATOM 5349 C C   . SER E 5 10  ? 403.593 343.254 453.529 1.00 51.41  ? 10  SER C C   1 
ATOM 5350 O O   . SER E 5 10  ? 402.363 343.178 453.536 1.00 51.41  ? 10  SER C O   1 
ATOM 5351 C CB  . SER E 5 10  ? 405.331 342.786 451.797 1.00 51.41  ? 10  SER C CB  1 
ATOM 5352 O OG  . SER E 5 10  ? 406.256 342.498 452.813 1.00 51.41  ? 10  SER C OG  1 
ATOM 5353 N N   . THR E 5 11  ? 404.322 342.899 454.578 1.00 52.29  ? 11  THR C N   1 
ATOM 5354 C CA  . THR E 5 11  ? 403.717 342.203 455.712 1.00 52.29  ? 11  THR C CA  1 
ATOM 5355 C C   . THR E 5 11  ? 403.366 343.184 456.822 1.00 52.29  ? 11  THR C C   1 
ATOM 5356 O O   . THR E 5 11  ? 403.774 343.040 457.968 1.00 52.29  ? 11  THR C O   1 
ATOM 5357 C CB  . THR E 5 11  ? 404.647 341.118 456.226 1.00 52.29  ? 11  THR C CB  1 
ATOM 5358 O OG1 . THR E 5 11  ? 405.713 341.720 456.964 1.00 52.29  ? 11  THR C OG1 1 
ATOM 5359 C CG2 . THR E 5 11  ? 405.220 340.336 455.086 1.00 52.29  ? 11  THR C CG2 1 
ATOM 5360 N N   . GLN E 5 12  ? 402.581 344.184 456.463 1.00 49.77  ? 12  GLN C N   1 
ATOM 5361 C CA  . GLN E 5 12  ? 402.250 345.269 457.364 1.00 49.77  ? 12  GLN C CA  1 
ATOM 5362 C C   . GLN E 5 12  ? 400.750 345.319 457.556 1.00 49.77  ? 12  GLN C C   1 
ATOM 5363 O O   . GLN E 5 12  ? 399.984 344.749 456.782 1.00 49.77  ? 12  GLN C O   1 
ATOM 5364 C CB  . GLN E 5 12  ? 402.741 346.609 456.826 1.00 49.77  ? 12  GLN C CB  1 
ATOM 5365 C CG  . GLN E 5 12  ? 402.121 346.957 455.508 1.00 49.77  ? 12  GLN C CG  1 
ATOM 5366 C CD  . GLN E 5 12  ? 402.349 348.378 455.131 1.00 49.77  ? 12  GLN C CD  1 
ATOM 5367 O OE1 . GLN E 5 12  ? 403.021 349.108 455.841 1.00 49.77  ? 12  GLN C OE1 1 
ATOM 5368 N NE2 . GLN E 5 12  ? 401.788 348.790 454.012 1.00 49.77  ? 12  GLN C NE2 1 
ATOM 5369 N N   . PHE E 5 13  ? 400.339 346.015 458.595 1.00 49.89  ? 13  PHE C N   1 
ATOM 5370 C CA  . PHE E 5 13  ? 398.934 346.206 458.897 1.00 49.89  ? 13  PHE C CA  1 
ATOM 5371 C C   . PHE E 5 13  ? 398.664 347.692 458.746 1.00 49.89  ? 13  PHE C C   1 
ATOM 5372 O O   . PHE E 5 13  ? 398.925 348.481 459.649 1.00 49.89  ? 13  PHE C O   1 
ATOM 5373 C CB  . PHE E 5 13  ? 398.608 345.706 460.283 1.00 49.89  ? 13  PHE C CB  1 
ATOM 5374 C CG  . PHE E 5 13  ? 397.191 345.919 460.685 1.00 49.89  ? 13  PHE C CG  1 
ATOM 5375 C CD1 . PHE E 5 13  ? 396.162 345.685 459.801 1.00 49.89  ? 13  PHE C CD1 1 
ATOM 5376 C CD2 . PHE E 5 13  ? 396.889 346.345 461.953 1.00 49.89  ? 13  PHE C CD2 1 
ATOM 5377 C CE1 . PHE E 5 13  ? 394.870 345.885 460.175 1.00 49.89  ? 13  PHE C CE1 1 
ATOM 5378 C CE2 . PHE E 5 13  ? 395.600 346.541 462.325 1.00 49.89  ? 13  PHE C CE2 1 
ATOM 5379 C CZ  . PHE E 5 13  ? 394.592 346.313 461.437 1.00 49.89  ? 13  PHE C CZ  1 
ATOM 5380 N N   . LEU E 5 14  ? 398.173 348.076 457.585 1.00 54.04  ? 14  LEU C N   1 
ATOM 5381 C CA  . LEU E 5 14  ? 397.667 349.420 457.405 1.00 54.04  ? 14  LEU C CA  1 
ATOM 5382 C C   . LEU E 5 14  ? 396.181 349.391 457.684 1.00 54.04  ? 14  LEU C C   1 
ATOM 5383 O O   . LEU E 5 14  ? 395.440 348.671 457.015 1.00 54.04  ? 14  LEU C O   1 
ATOM 5384 C CB  . LEU E 5 14  ? 397.947 349.906 455.989 1.00 54.04  ? 14  LEU C CB  1 
ATOM 5385 C CG  . LEU E 5 14  ? 397.381 351.242 455.538 1.00 54.04  ? 14  LEU C CG  1 
ATOM 5386 C CD1 . LEU E 5 14  ? 397.985 352.367 456.314 1.00 54.04  ? 14  LEU C CD1 1 
ATOM 5387 C CD2 . LEU E 5 14  ? 397.679 351.402 454.088 1.00 54.04  ? 14  LEU C CD2 1 
ATOM 5388 N N   . THR E 5 15  ? 395.739 350.170 458.670 1.00 56.28  ? 15  THR C N   1 
ATOM 5389 C CA  . THR E 5 15  ? 394.384 350.016 459.184 1.00 56.28  ? 15  THR C CA  1 
ATOM 5390 C C   . THR E 5 15  ? 393.311 350.497 458.222 1.00 56.28  ? 15  THR C C   1 
ATOM 5391 O O   . THR E 5 15  ? 392.130 350.249 458.465 1.00 56.28  ? 15  THR C O   1 
ATOM 5392 C CB  . THR E 5 15  ? 394.224 350.763 460.499 1.00 56.28  ? 15  THR C CB  1 
ATOM 5393 O OG1 . THR E 5 15  ? 394.239 352.165 460.244 1.00 56.28  ? 15  THR C OG1 1 
ATOM 5394 C CG2 . THR E 5 15  ? 395.354 350.431 461.420 1.00 56.28  ? 15  THR C CG2 1 
ATOM 5395 N N   . SER E 5 16  ? 393.683 351.157 457.138 1.00 62.83  ? 16  SER C N   1 
ATOM 5396 C CA  . SER E 5 16  ? 392.731 351.699 456.185 1.00 62.83  ? 16  SER C CA  1 
ATOM 5397 C C   . SER E 5 16  ? 392.828 351.017 454.828 1.00 62.83  ? 16  SER C C   1 
ATOM 5398 O O   . SER E 5 16  ? 392.778 351.673 453.793 1.00 62.83  ? 16  SER C O   1 
ATOM 5399 C CB  . SER E 5 16  ? 392.936 353.197 456.033 1.00 62.83  ? 16  SER C CB  1 
ATOM 5400 O OG  . SER E 5 16  ? 394.311 353.499 455.965 1.00 62.83  ? 16  SER C OG  1 
ATOM 5401 N N   . ASP E 5 17  ? 392.974 349.700 454.810 1.00 69.19  ? 17  ASP C N   1 
ATOM 5402 C CA  . ASP E 5 17  ? 393.074 348.979 453.551 1.00 69.19  ? 17  ASP C CA  1 
ATOM 5403 C C   . ASP E 5 17  ? 391.723 348.392 453.150 1.00 69.19  ? 17  ASP C C   1 
ATOM 5404 O O   . ASP E 5 17  ? 390.694 348.655 453.772 1.00 69.19  ? 17  ASP C O   1 
ATOM 5405 C CB  . ASP E 5 17  ? 394.160 347.911 453.636 1.00 69.19  ? 17  ASP C CB  1 
ATOM 5406 C CG  . ASP E 5 17  ? 393.997 346.973 454.820 1.00 69.19  ? 17  ASP C CG  1 
ATOM 5407 O OD1 . ASP E 5 17  ? 392.889 346.788 455.358 1.00 69.19  ? 17  ASP C OD1 1 
ATOM 5408 O OD2 . ASP E 5 17  ? 395.025 346.405 455.235 1.00 69.19  ? 17  ASP C OD2 1 
ATOM 5409 N N   . ASP E 5 18  ? 391.722 347.580 452.098 1.00 76.05  ? 18  ASP C N   1 
ATOM 5410 C CA  . ASP E 5 18  ? 390.553 346.783 451.740 1.00 76.05  ? 18  ASP C CA  1 
ATOM 5411 C C   . ASP E 5 18  ? 391.075 345.526 451.058 1.00 76.05  ? 18  ASP C C   1 
ATOM 5412 O O   . ASP E 5 18  ? 391.359 345.541 449.859 1.00 76.05  ? 18  ASP C O   1 
ATOM 5413 C CB  . ASP E 5 18  ? 389.600 347.546 450.839 1.00 76.05  ? 18  ASP C CB  1 
ATOM 5414 C CG  . ASP E 5 18  ? 388.228 346.913 450.785 1.00 76.05  ? 18  ASP C CG  1 
ATOM 5415 O OD1 . ASP E 5 18  ? 387.842 346.261 451.775 1.00 76.05  ? 18  ASP C OD1 1 
ATOM 5416 O OD2 . ASP E 5 18  ? 387.535 347.063 449.755 1.00 76.05  ? 18  ASP C OD2 1 
ATOM 5417 N N   . PHE E 5 19  ? 391.199 344.453 451.826 1.00 76.24  ? 19  PHE C N   1 
ATOM 5418 C CA  . PHE E 5 19  ? 391.719 343.201 451.318 1.00 76.24  ? 19  PHE C CA  1 
ATOM 5419 C C   . PHE E 5 19  ? 390.716 342.101 451.608 1.00 76.24  ? 19  PHE C C   1 
ATOM 5420 O O   . PHE E 5 19  ? 389.919 342.195 452.541 1.00 76.24  ? 19  PHE C O   1 
ATOM 5421 C CB  . PHE E 5 19  ? 393.060 342.857 451.956 1.00 76.24  ? 19  PHE C CB  1 
ATOM 5422 C CG  . PHE E 5 19  ? 394.193 343.682 451.458 1.00 76.24  ? 19  PHE C CG  1 
ATOM 5423 C CD1 . PHE E 5 19  ? 394.287 344.014 450.129 1.00 76.24  ? 19  PHE C CD1 1 
ATOM 5424 C CD2 . PHE E 5 19  ? 395.175 344.111 452.320 1.00 76.24  ? 19  PHE C CD2 1 
ATOM 5425 C CE1 . PHE E 5 19  ? 395.339 344.767 449.672 1.00 76.24  ? 19  PHE C CE1 1 
ATOM 5426 C CE2 . PHE E 5 19  ? 396.223 344.862 451.865 1.00 76.24  ? 19  PHE C CE2 1 
ATOM 5427 C CZ  . PHE E 5 19  ? 396.305 345.188 450.542 1.00 76.24  ? 19  PHE C CZ  1 
ATOM 5428 N N   . GLN E 5 20  ? 390.764 341.057 450.789 1.00 73.22  ? 20  GLN C N   1 
ATOM 5429 C CA  . GLN E 5 20  ? 389.959 339.876 451.040 1.00 73.22  ? 20  GLN C CA  1 
ATOM 5430 C C   . GLN E 5 20  ? 390.439 339.200 452.310 1.00 73.22  ? 20  GLN C C   1 
ATOM 5431 O O   . GLN E 5 20  ? 391.624 339.249 452.642 1.00 73.22  ? 20  GLN C O   1 
ATOM 5432 C CB  . GLN E 5 20  ? 390.050 338.912 449.869 1.00 73.22  ? 20  GLN C CB  1 
ATOM 5433 C CG  . GLN E 5 20  ? 389.465 339.447 448.597 1.00 73.22  ? 20  GLN C CG  1 
ATOM 5434 C CD  . GLN E 5 20  ? 388.093 338.889 448.316 1.00 73.22  ? 20  GLN C CD  1 
ATOM 5435 O OE1 . GLN E 5 20  ? 387.770 337.773 448.724 1.00 73.22  ? 20  GLN C OE1 1 
ATOM 5436 N NE2 . GLN E 5 20  ? 387.275 339.658 447.607 1.00 73.22  ? 20  GLN C NE2 1 
ATOM 5437 N N   . SER E 5 21  ? 389.515 338.586 453.029 1.00 67.70  ? 21  SER C N   1 
ATOM 5438 C CA  . SER E 5 21  ? 389.824 338.018 454.316 1.00 67.70  ? 21  SER C CA  1 
ATOM 5439 C C   . SER E 5 21  ? 389.262 336.610 454.433 1.00 67.70  ? 21  SER C C   1 
ATOM 5440 O O   . SER E 5 21  ? 388.191 336.327 453.892 1.00 67.70  ? 21  SER C O   1 
ATOM 5441 C CB  . SER E 5 21  ? 389.250 338.899 455.414 1.00 67.70  ? 21  SER C CB  1 
ATOM 5442 O OG  . SER E 5 21  ? 387.857 339.028 455.248 1.00 67.70  ? 21  SER C OG  1 
ATOM 5443 N N   . PRO E 5 22  ? 389.960 335.707 455.115 1.00 63.39  ? 22  PRO C N   1 
ATOM 5444 C CA  . PRO E 5 22  ? 389.449 334.339 455.257 1.00 63.39  ? 22  PRO C CA  1 
ATOM 5445 C C   . PRO E 5 22  ? 388.331 334.273 456.285 1.00 63.39  ? 22  PRO C C   1 
ATOM 5446 O O   . PRO E 5 22  ? 388.488 334.718 457.420 1.00 63.39  ? 22  PRO C O   1 
ATOM 5447 C CB  . PRO E 5 22  ? 390.679 333.552 455.711 1.00 63.39  ? 22  PRO C CB  1 
ATOM 5448 C CG  . PRO E 5 22  ? 391.561 334.568 456.342 1.00 63.39  ? 22  PRO C CG  1 
ATOM 5449 C CD  . PRO E 5 22  ? 391.326 335.852 455.638 1.00 63.39  ? 22  PRO C CD  1 
ATOM 5450 N N   . SER E 5 23  ? 387.200 333.703 455.882 1.00 60.99  ? 23  SER C N   1 
ATOM 5451 C CA  . SER E 5 23  ? 386.019 333.700 456.734 1.00 60.99  ? 23  SER C CA  1 
ATOM 5452 C C   . SER E 5 23  ? 386.137 332.663 457.836 1.00 60.99  ? 23  SER C C   1 
ATOM 5453 O O   . SER E 5 23  ? 386.487 331.509 457.585 1.00 60.99  ? 23  SER C O   1 
ATOM 5454 C CB  . SER E 5 23  ? 384.765 333.429 455.914 1.00 60.99  ? 23  SER C CB  1 
ATOM 5455 O OG  . SER E 5 23  ? 383.627 333.448 456.751 1.00 60.99  ? 23  SER C OG  1 
ATOM 5456 N N   . ALA E 5 24  ? 385.827 333.080 459.063 1.00 59.03  ? 24  ALA C N   1 
ATOM 5457 C CA  . ALA E 5 24  ? 385.977 332.202 460.214 1.00 59.03  ? 24  ALA C CA  1 
ATOM 5458 C C   . ALA E 5 24  ? 384.910 331.128 460.239 1.00 59.03  ? 24  ALA C C   1 
ATOM 5459 O O   . ALA E 5 24  ? 385.187 329.982 460.600 1.00 59.03  ? 24  ALA C O   1 
ATOM 5460 C CB  . ALA E 5 24  ? 385.925 333.006 461.506 1.00 59.03  ? 24  ALA C CB  1 
ATOM 5461 N N   . MET E 5 25  ? 383.684 331.482 459.871 1.00 63.40  ? 25  MET C N   1 
ATOM 5462 C CA  . MET E 5 25  ? 382.568 330.545 459.810 1.00 63.40  ? 25  MET C CA  1 
ATOM 5463 C C   . MET E 5 25  ? 382.087 330.488 458.372 1.00 63.40  ? 25  MET C C   1 
ATOM 5464 O O   . MET E 5 25  ? 381.273 331.317 457.948 1.00 63.40  ? 25  MET C O   1 
ATOM 5465 C CB  . MET E 5 25  ? 381.439 330.962 460.743 1.00 63.40  ? 25  MET C CB  1 
ATOM 5466 C CG  . MET E 5 25  ? 381.837 330.987 462.184 1.00 63.40  ? 25  MET C CG  1 
ATOM 5467 S SD  . MET E 5 25  ? 380.434 330.800 463.273 1.00 63.40  ? 25  MET C SD  1 
ATOM 5468 C CE  . MET E 5 25  ? 379.848 329.195 462.770 1.00 63.40  ? 25  MET C CE  1 
ATOM 5469 N N   . PRO E 5 26  ? 382.563 329.538 457.588 1.00 63.77  ? 26  PRO C N   1 
ATOM 5470 C CA  . PRO E 5 26  ? 381.895 329.193 456.339 1.00 63.77  ? 26  PRO C CA  1 
ATOM 5471 C C   . PRO E 5 26  ? 380.736 328.269 456.676 1.00 63.77  ? 26  PRO C C   1 
ATOM 5472 O O   . PRO E 5 26  ? 380.453 328.013 457.844 1.00 63.77  ? 26  PRO C O   1 
ATOM 5473 C CB  . PRO E 5 26  ? 382.975 328.461 455.548 1.00 63.77  ? 26  PRO C CB  1 
ATOM 5474 C CG  . PRO E 5 26  ? 384.218 328.580 456.358 1.00 63.77  ? 26  PRO C CG  1 
ATOM 5475 C CD  . PRO E 5 26  ? 383.781 328.746 457.757 1.00 63.77  ? 26  PRO C CD  1 
ATOM 5476 N N   . GLN E 5 27  ? 380.082 327.760 455.628 1.00 67.52  ? 27  GLN C N   1 
ATOM 5477 C CA  . GLN E 5 27  ? 378.980 326.792 455.663 1.00 67.52  ? 27  GLN C CA  1 
ATOM 5478 C C   . GLN E 5 27  ? 377.902 327.082 456.710 1.00 67.52  ? 27  GLN C C   1 
ATOM 5479 O O   . GLN E 5 27  ? 377.271 326.166 457.242 1.00 67.52  ? 27  GLN C O   1 
ATOM 5480 C CB  . GLN E 5 27  ? 379.529 325.357 455.810 1.00 67.52  ? 27  GLN C CB  1 
ATOM 5481 C CG  . GLN E 5 27  ? 380.223 324.929 457.098 1.00 67.52  ? 27  GLN C CG  1 
ATOM 5482 C CD  . GLN E 5 27  ? 381.342 323.963 456.842 1.00 67.52  ? 27  GLN C CD  1 
ATOM 5483 O OE1 . GLN E 5 27  ? 381.552 323.529 455.716 1.00 67.52  ? 27  GLN C OE1 1 
ATOM 5484 N NE2 . GLN E 5 27  ? 382.078 323.627 457.885 1.00 67.52  ? 27  GLN C NE2 1 
ATOM 5485 N N   . PHE E 5 28  ? 377.654 328.366 456.970 1.00 69.31  ? 28  PHE C N   1 
ATOM 5486 C CA  . PHE E 5 28  ? 376.730 328.778 458.012 1.00 69.31  ? 28  PHE C CA  1 
ATOM 5487 C C   . PHE E 5 28  ? 375.324 329.027 457.489 1.00 69.31  ? 28  PHE C C   1 
ATOM 5488 O O   . PHE E 5 28  ? 374.363 328.834 458.243 1.00 69.31  ? 28  PHE C O   1 
ATOM 5489 C CB  . PHE E 5 28  ? 377.263 330.029 458.713 1.00 69.31  ? 28  PHE C CB  1 
ATOM 5490 C CG  . PHE E 5 28  ? 376.356 330.555 459.775 1.00 69.31  ? 28  PHE C CG  1 
ATOM 5491 C CD1 . PHE E 5 28  ? 375.917 329.736 460.794 1.00 69.31  ? 28  PHE C CD1 1 
ATOM 5492 C CD2 . PHE E 5 28  ? 375.922 331.861 459.741 1.00 69.31  ? 28  PHE C CD2 1 
ATOM 5493 C CE1 . PHE E 5 28  ? 375.065 330.210 461.752 1.00 69.31  ? 28  PHE C CE1 1 
ATOM 5494 C CE2 . PHE E 5 28  ? 375.075 332.340 460.701 1.00 69.31  ? 28  PHE C CE2 1 
ATOM 5495 C CZ  . PHE E 5 28  ? 374.646 331.512 461.706 1.00 69.31  ? 28  PHE C CZ  1 
ATOM 5496 N N   . ASP E 5 29  ? 375.183 329.393 456.210 1.00 73.57  ? 29  ASP C N   1 
ATOM 5497 C CA  . ASP E 5 29  ? 373.900 329.701 455.565 1.00 73.57  ? 29  ASP C CA  1 
ATOM 5498 C C   . ASP E 5 29  ? 373.197 330.852 456.289 1.00 73.57  ? 29  ASP C C   1 
ATOM 5499 O O   . ASP E 5 29  ? 372.248 330.672 457.050 1.00 73.57  ? 29  ASP C O   1 
ATOM 5500 C CB  . ASP E 5 29  ? 372.991 328.469 455.443 1.00 73.57  ? 29  ASP C CB  1 
ATOM 5501 C CG  . ASP E 5 29  ? 372.175 328.475 454.169 1.00 73.57  ? 29  ASP C CG  1 
ATOM 5502 O OD1 . ASP E 5 29  ? 372.640 329.063 453.170 1.00 73.57  ? 29  ASP C OD1 1 
ATOM 5503 O OD2 . ASP E 5 29  ? 371.071 327.890 454.163 1.00 73.57  ? 29  ASP C OD2 1 
ATOM 5504 N N   . VAL E 5 30  ? 373.785 332.032 456.083 1.00 67.68  ? 30  VAL C N   1 
ATOM 5505 C CA  . VAL E 5 30  ? 373.355 333.279 456.697 1.00 67.68  ? 30  VAL C CA  1 
ATOM 5506 C C   . VAL E 5 30  ? 371.868 333.590 456.434 1.00 67.68  ? 30  VAL C C   1 
ATOM 5507 O O   . VAL E 5 30  ? 371.273 333.169 455.434 1.00 67.68  ? 30  VAL C O   1 
ATOM 5508 C CB  . VAL E 5 30  ? 374.290 334.382 456.172 1.00 67.68  ? 30  VAL C CB  1 
ATOM 5509 C CG1 . VAL E 5 30  ? 373.989 334.736 454.737 1.00 67.68  ? 30  VAL C CG1 1 
ATOM 5510 C CG2 . VAL E 5 30  ? 374.251 335.600 457.021 1.00 67.68  ? 30  VAL C CG2 1 
ATOM 5511 N N   . THR E 5 31  ? 371.257 334.273 457.398 1.00 65.07  ? 31  THR C N   1 
ATOM 5512 C CA  . THR E 5 31  ? 369.839 334.614 457.343 1.00 65.07  ? 31  THR C CA  1 
ATOM 5513 C C   . THR E 5 31  ? 369.580 335.595 456.208 1.00 65.07  ? 31  THR C C   1 
ATOM 5514 O O   . THR E 5 31  ? 370.352 336.541 456.035 1.00 65.07  ? 31  THR C O   1 
ATOM 5515 C CB  . THR E 5 31  ? 369.429 335.230 458.675 1.00 65.07  ? 31  THR C CB  1 
ATOM 5516 O OG1 . THR E 5 31  ? 369.941 334.427 459.741 1.00 65.07  ? 31  THR C OG1 1 
ATOM 5517 C CG2 . THR E 5 31  ? 367.933 335.325 458.808 1.00 65.07  ? 31  THR C CG2 1 
ATOM 5518 N N   . PRO E 5 32  ? 368.525 335.412 455.414 1.00 65.52  ? 32  PRO C N   1 
ATOM 5519 C CA  . PRO E 5 32  ? 368.295 336.325 454.290 1.00 65.52  ? 32  PRO C CA  1 
ATOM 5520 C C   . PRO E 5 32  ? 367.828 337.705 454.713 1.00 65.52  ? 32  PRO C C   1 
ATOM 5521 O O   . PRO E 5 32  ? 367.715 338.002 455.904 1.00 65.52  ? 32  PRO C O   1 
ATOM 5522 C CB  . PRO E 5 32  ? 367.220 335.602 453.474 1.00 65.52  ? 32  PRO C CB  1 
ATOM 5523 C CG  . PRO E 5 32  ? 366.542 334.743 454.446 1.00 65.52  ? 32  PRO C CG  1 
ATOM 5524 C CD  . PRO E 5 32  ? 367.611 334.264 455.357 1.00 65.52  ? 32  PRO C CD  1 
ATOM 5525 N N   . GLU E 5 33  ? 367.550 338.559 453.739 1.00 67.16  ? 33  GLU C N   1 
ATOM 5526 C CA  . GLU E 5 33  ? 367.164 339.927 454.027 1.00 67.16  ? 33  GLU C CA  1 
ATOM 5527 C C   . GLU E 5 33  ? 365.696 339.998 454.431 1.00 67.16  ? 33  GLU C C   1 
ATOM 5528 O O   . GLU E 5 33  ? 364.996 338.990 454.532 1.00 67.16  ? 33  GLU C O   1 
ATOM 5529 C CB  . GLU E 5 33  ? 367.421 340.807 452.814 1.00 67.16  ? 33  GLU C CB  1 
ATOM 5530 C CG  . GLU E 5 33  ? 368.814 340.697 452.269 1.00 67.16  ? 33  GLU C CG  1 
ATOM 5531 C CD  . GLU E 5 33  ? 369.727 341.728 452.859 1.00 67.16  ? 33  GLU C CD  1 
ATOM 5532 O OE1 . GLU E 5 33  ? 370.957 341.607 452.679 1.00 67.16  ? 33  GLU C OE1 1 
ATOM 5533 O OE2 . GLU E 5 33  ? 369.208 342.660 453.504 1.00 67.16  ? 33  GLU C OE2 1 
ATOM 5534 N N   . MET E 5 34  ? 365.228 341.222 454.647 1.00 67.70  ? 34  MET C N   1 
ATOM 5535 C CA  . MET E 5 34  ? 363.849 341.503 455.009 1.00 67.70  ? 34  MET C CA  1 
ATOM 5536 C C   . MET E 5 34  ? 363.603 342.976 454.739 1.00 67.70  ? 34  MET C C   1 
ATOM 5537 O O   . MET E 5 34  ? 364.453 343.809 455.048 1.00 67.70  ? 34  MET C O   1 
ATOM 5538 C CB  . MET E 5 34  ? 363.575 341.179 456.481 1.00 67.70  ? 34  MET C CB  1 
ATOM 5539 C CG  . MET E 5 34  ? 362.191 341.540 456.953 1.00 67.70  ? 34  MET C CG  1 
ATOM 5540 S SD  . MET E 5 34  ? 361.993 341.401 458.724 1.00 67.70  ? 34  MET C SD  1 
ATOM 5541 C CE  . MET E 5 34  ? 360.503 342.358 458.946 1.00 67.70  ? 34  MET C CE  1 
ATOM 5542 N N   . GLN E 5 35  ? 362.450 343.293 454.161 1.00 68.61  ? 35  GLN C N   1 
ATOM 5543 C CA  . GLN E 5 35  ? 362.128 344.687 453.902 1.00 68.61  ? 35  GLN C CA  1 
ATOM 5544 C C   . GLN E 5 35  ? 361.697 345.399 455.173 1.00 68.61  ? 35  GLN C C   1 
ATOM 5545 O O   . GLN E 5 35  ? 360.541 345.297 455.586 1.00 68.61  ? 35  GLN C O   1 
ATOM 5546 C CB  . GLN E 5 35  ? 361.039 344.793 452.840 1.00 68.61  ? 35  GLN C CB  1 
ATOM 5547 C CG  . GLN E 5 35  ? 361.406 344.092 451.555 1.00 68.61  ? 35  GLN C CG  1 
ATOM 5548 C CD  . GLN E 5 35  ? 362.122 344.997 450.584 1.00 68.61  ? 35  GLN C CD  1 
ATOM 5549 O OE1 . GLN E 5 35  ? 362.537 346.100 450.934 1.00 68.61  ? 35  GLN C OE1 1 
ATOM 5550 N NE2 . GLN E 5 35  ? 362.293 344.524 449.358 1.00 68.61  ? 35  GLN C NE2 1 
ATOM 5551 N N   . ILE E 5 36  ? 362.624 346.110 455.801 1.00 61.67  ? 36  ILE C N   1 
ATOM 5552 C CA  . ILE E 5 36  ? 362.329 346.964 456.945 1.00 61.67  ? 36  ILE C CA  1 
ATOM 5553 C C   . ILE E 5 36  ? 362.160 348.379 456.407 1.00 61.67  ? 36  ILE C C   1 
ATOM 5554 O O   . ILE E 5 36  ? 362.938 348.795 455.540 1.00 61.67  ? 36  ILE C O   1 
ATOM 5555 C CB  . ILE E 5 36  ? 363.441 346.879 457.999 1.00 61.67  ? 36  ILE C CB  1 
ATOM 5556 C CG1 . ILE E 5 36  ? 363.922 345.442 458.139 1.00 61.67  ? 36  ILE C CG1 1 
ATOM 5557 C CG2 . ILE E 5 36  ? 362.959 347.369 459.328 1.00 61.67  ? 36  ILE C CG2 1 
ATOM 5558 C CD1 . ILE E 5 36  ? 364.952 345.239 459.208 1.00 61.67  ? 36  ILE C CD1 1 
ATOM 5559 N N   . PRO E 5 37  ? 361.162 349.138 456.847 1.00 61.03  ? 37  PRO C N   1 
ATOM 5560 C CA  . PRO E 5 37  ? 360.982 350.487 456.313 1.00 61.03  ? 37  PRO C CA  1 
ATOM 5561 C C   . PRO E 5 37  ? 362.022 351.461 456.835 1.00 61.03  ? 37  PRO C C   1 
ATOM 5562 O O   . PRO E 5 37  ? 362.546 351.319 457.938 1.00 61.03  ? 37  PRO C O   1 
ATOM 5563 C CB  . PRO E 5 37  ? 359.585 350.877 456.804 1.00 61.03  ? 37  PRO C CB  1 
ATOM 5564 C CG  . PRO E 5 37  ? 358.949 349.635 457.199 1.00 61.03  ? 37  PRO C CG  1 
ATOM 5565 C CD  . PRO E 5 37  ? 360.016 348.739 457.672 1.00 61.03  ? 37  PRO C CD  1 
ATOM 5566 N N   . GLY E 5 38  ? 362.309 352.469 456.022 1.00 58.42  ? 38  GLY C N   1 
ATOM 5567 C CA  . GLY E 5 38  ? 363.103 353.587 456.472 1.00 58.42  ? 38  GLY C CA  1 
ATOM 5568 C C   . GLY E 5 38  ? 364.592 353.395 456.349 1.00 58.42  ? 38  GLY C C   1 
ATOM 5569 O O   . GLY E 5 38  ? 365.311 353.543 457.334 1.00 58.42  ? 38  GLY C O   1 
ATOM 5570 N N   . ARG E 5 39  ? 365.072 353.099 455.148 1.00 58.50  ? 39  ARG C N   1 
ATOM 5571 C CA  . ARG E 5 39  ? 366.483 352.831 454.925 1.00 58.50  ? 39  ARG C CA  1 
ATOM 5572 C C   . ARG E 5 39  ? 367.241 354.131 454.720 1.00 58.50  ? 39  ARG C C   1 
ATOM 5573 O O   . ARG E 5 39  ? 366.747 355.044 454.059 1.00 58.50  ? 39  ARG C O   1 
ATOM 5574 C CB  . ARG E 5 39  ? 366.677 351.918 453.719 1.00 58.50  ? 39  ARG C CB  1 
ATOM 5575 C CG  . ARG E 5 39  ? 368.084 351.388 453.615 1.00 58.50  ? 39  ARG C CG  1 
ATOM 5576 C CD  . ARG E 5 39  ? 368.192 350.184 452.733 1.00 58.50  ? 39  ARG C CD  1 
ATOM 5577 N NE  . ARG E 5 39  ? 369.581 349.778 452.595 1.00 58.50  ? 39  ARG C NE  1 
ATOM 5578 C CZ  . ARG E 5 39  ? 369.986 348.780 451.825 1.00 58.50  ? 39  ARG C CZ  1 
ATOM 5579 N NH1 . ARG E 5 39  ? 371.270 348.479 451.755 1.00 58.50  ? 39  ARG C NH1 1 
ATOM 5580 N NH2 . ARG E 5 39  ? 369.105 348.085 451.124 1.00 58.50  ? 39  ARG C NH2 1 
ATOM 5581 N N   . VAL E 5 40  ? 368.437 354.208 455.289 1.00 58.20  ? 40  VAL C N   1 
ATOM 5582 C CA  . VAL E 5 40  ? 369.314 355.360 455.148 1.00 58.20  ? 40  VAL C CA  1 
ATOM 5583 C C   . VAL E 5 40  ? 370.427 354.984 454.189 1.00 58.20  ? 40  VAL C C   1 
ATOM 5584 O O   . VAL E 5 40  ? 371.191 354.052 454.455 1.00 58.20  ? 40  VAL C O   1 
ATOM 5585 C CB  . VAL E 5 40  ? 369.892 355.787 456.503 1.00 58.20  ? 40  VAL C CB  1 
ATOM 5586 C CG1 . VAL E 5 40  ? 370.419 357.175 456.427 1.00 58.20  ? 40  VAL C CG1 1 
ATOM 5587 C CG2 . VAL E 5 40  ? 368.859 355.701 457.556 1.00 58.20  ? 40  VAL C CG2 1 
ATOM 5588 N N   . ASN E 5 41  ? 370.532 355.700 453.075 1.00 61.17  ? 41  ASN C N   1 
ATOM 5589 C CA  . ASN E 5 41  ? 371.628 355.482 452.147 1.00 61.17  ? 41  ASN C CA  1 
ATOM 5590 C C   . ASN E 5 41  ? 372.728 356.519 452.266 1.00 61.17  ? 41  ASN C C   1 
ATOM 5591 O O   . ASN E 5 41  ? 373.816 356.302 451.730 1.00 61.17  ? 41  ASN C O   1 
ATOM 5592 C CB  . ASN E 5 41  ? 371.121 355.477 450.706 1.00 61.17  ? 41  ASN C CB  1 
ATOM 5593 C CG  . ASN E 5 41  ? 370.281 354.268 450.389 1.00 61.17  ? 41  ASN C CG  1 
ATOM 5594 O OD1 . ASN E 5 41  ? 370.798 353.173 450.193 1.00 61.17  ? 41  ASN C OD1 1 
ATOM 5595 N ND2 . ASN E 5 41  ? 368.975 354.462 450.318 1.00 61.17  ? 41  ASN C ND2 1 
ATOM 5596 N N   . ASN E 5 42  ? 372.474 357.628 452.950 1.00 62.20  ? 42  ASN C N   1 
ATOM 5597 C CA  . ASN E 5 42  ? 373.407 358.739 453.024 1.00 62.20  ? 42  ASN C CA  1 
ATOM 5598 C C   . ASN E 5 42  ? 373.083 359.548 454.266 1.00 62.20  ? 42  ASN C C   1 
ATOM 5599 O O   . ASN E 5 42  ? 371.945 359.539 454.730 1.00 62.20  ? 42  ASN C O   1 
ATOM 5600 C CB  . ASN E 5 42  ? 373.309 359.615 451.778 1.00 62.20  ? 42  ASN C CB  1 
ATOM 5601 C CG  . ASN E 5 42  ? 374.542 360.436 451.549 1.00 62.20  ? 42  ASN C CG  1 
ATOM 5602 O OD1 . ASN E 5 42  ? 374.955 361.200 452.410 1.00 62.20  ? 42  ASN C OD1 1 
ATOM 5603 N ND2 . ASN E 5 42  ? 375.140 360.290 450.380 1.00 62.20  ? 42  ASN C ND2 1 
ATOM 5604 N N   . LEU E 5 43  ? 374.076 360.250 454.799 1.00 60.29  ? 43  LEU C N   1 
ATOM 5605 C CA  . LEU E 5 43  ? 373.835 361.060 455.983 1.00 60.29  ? 43  LEU C CA  1 
ATOM 5606 C C   . LEU E 5 43  ? 373.228 362.412 455.672 1.00 60.29  ? 43  LEU C C   1 
ATOM 5607 O O   . LEU E 5 43  ? 372.863 363.133 456.600 1.00 60.29  ? 43  LEU C O   1 
ATOM 5608 C CB  . LEU E 5 43  ? 375.120 361.289 456.761 1.00 60.29  ? 43  LEU C CB  1 
ATOM 5609 C CG  . LEU E 5 43  ? 375.770 360.109 457.449 1.00 60.29  ? 43  LEU C CG  1 
ATOM 5610 C CD1 . LEU E 5 43  ? 376.786 360.657 458.397 1.00 60.29  ? 43  LEU C CD1 1 
ATOM 5611 C CD2 . LEU E 5 43  ? 374.758 359.286 458.178 1.00 60.29  ? 43  LEU C CD2 1 
ATOM 5612 N N   . MET E 5 44  ? 373.129 362.789 454.403 1.00 66.35  ? 44  MET C N   1 
ATOM 5613 C CA  . MET E 5 44  ? 372.518 364.068 454.085 1.00 66.35  ? 44  MET C CA  1 
ATOM 5614 C C   . MET E 5 44  ? 371.003 363.994 454.153 1.00 66.35  ? 44  MET C C   1 
ATOM 5615 O O   . MET E 5 44  ? 370.336 365.030 454.185 1.00 66.35  ? 44  MET C O   1 
ATOM 5616 C CB  . MET E 5 44  ? 372.977 364.540 452.713 1.00 66.35  ? 44  MET C CB  1 
ATOM 5617 C CG  . MET E 5 44  ? 374.344 365.193 452.731 1.00 66.35  ? 44  MET C CG  1 
ATOM 5618 S SD  . MET E 5 44  ? 374.432 366.644 453.797 1.00 66.35  ? 44  MET C SD  1 
ATOM 5619 C CE  . MET E 5 44  ? 375.600 366.099 455.034 1.00 66.35  ? 44  MET C CE  1 
ATOM 5620 N N   . GLU E 5 45  ? 370.442 362.791 454.171 1.00 64.96  ? 45  GLU C N   1 
ATOM 5621 C CA  . GLU E 5 45  ? 369.017 362.643 454.404 1.00 64.96  ? 45  GLU C CA  1 
ATOM 5622 C C   . GLU E 5 45  ? 368.644 362.835 455.861 1.00 64.96  ? 45  GLU C C   1 
ATOM 5623 O O   . GLU E 5 45  ? 367.484 363.129 456.151 1.00 64.96  ? 45  GLU C O   1 
ATOM 5624 C CB  . GLU E 5 45  ? 368.561 361.271 453.935 1.00 64.96  ? 45  GLU C CB  1 
ATOM 5625 C CG  . GLU E 5 45  ? 369.084 360.900 452.572 1.00 64.96  ? 45  GLU C CG  1 
ATOM 5626 C CD  . GLU E 5 45  ? 368.730 359.487 452.190 1.00 64.96  ? 45  GLU C CD  1 
ATOM 5627 O OE1 . GLU E 5 45  ? 369.107 359.059 451.081 1.00 64.96  ? 45  GLU C OE1 1 
ATOM 5628 O OE2 . GLU E 5 45  ? 368.071 358.806 453.001 1.00 64.96  ? 45  GLU C OE2 1 
ATOM 5629 N N   . ILE E 5 46  ? 369.586 362.659 456.780 1.00 60.96  ? 46  ILE C N   1 
ATOM 5630 C CA  . ILE E 5 46  ? 369.329 362.971 458.177 1.00 60.96  ? 46  ILE C CA  1 
ATOM 5631 C C   . ILE E 5 46  ? 369.335 364.476 458.384 1.00 60.96  ? 46  ILE C C   1 
ATOM 5632 O O   . ILE E 5 46  ? 368.553 365.016 459.170 1.00 60.96  ? 46  ILE C O   1 
ATOM 5633 C CB  . ILE E 5 46  ? 370.370 362.259 459.057 1.00 60.96  ? 46  ILE C CB  1 
ATOM 5634 C CG1 . ILE E 5 46  ? 370.264 360.750 458.878 1.00 60.96  ? 46  ILE C CG1 1 
ATOM 5635 C CG2 . ILE E 5 46  ? 370.218 362.621 460.517 1.00 60.96  ? 46  ILE C CG2 1 
ATOM 5636 C CD1 . ILE E 5 46  ? 371.255 359.981 459.697 1.00 60.96  ? 46  ILE C CD1 1 
ATOM 5637 N N   . ALA E 5 47  ? 370.175 365.183 457.640 1.00 61.25  ? 47  ALA C N   1 
ATOM 5638 C CA  . ALA E 5 47  ? 370.313 366.621 457.792 1.00 61.25  ? 47  ALA C CA  1 
ATOM 5639 C C   . ALA E 5 47  ? 369.194 367.409 457.141 1.00 61.25  ? 47  ALA C C   1 
ATOM 5640 O O   . ALA E 5 47  ? 369.016 368.577 457.481 1.00 61.25  ? 47  ALA C O   1 
ATOM 5641 C CB  . ALA E 5 47  ? 371.643 367.078 457.207 1.00 61.25  ? 47  ALA C CB  1 
ATOM 5642 N N   . GLU E 5 48  ? 368.432 366.817 456.230 1.00 64.24  ? 48  GLU C N   1 
ATOM 5643 C CA  . GLU E 5 48  ? 367.441 367.584 455.493 1.00 64.24  ? 48  GLU C CA  1 
ATOM 5644 C C   . GLU E 5 48  ? 366.154 367.813 456.268 1.00 64.24  ? 48  GLU C C   1 
ATOM 5645 O O   . GLU E 5 48  ? 365.292 368.552 455.791 1.00 64.24  ? 48  GLU C O   1 
ATOM 5646 C CB  . GLU E 5 48  ? 367.114 366.889 454.179 1.00 64.24  ? 48  GLU C CB  1 
ATOM 5647 C CG  . GLU E 5 48  ? 366.239 365.672 454.349 1.00 64.24  ? 48  GLU C CG  1 
ATOM 5648 C CD  . GLU E 5 48  ? 365.880 365.025 453.031 1.00 64.24  ? 48  GLU C CD  1 
ATOM 5649 O OE1 . GLU E 5 48  ? 365.033 364.110 453.027 1.00 64.24  ? 48  GLU C OE1 1 
ATOM 5650 O OE2 . GLU E 5 48  ? 366.449 365.432 451.998 1.00 64.24  ? 48  GLU C OE2 1 
ATOM 5651 N N   . VAL E 5 49  ? 365.994 367.206 457.435 1.00 62.85  ? 49  VAL C N   1 
ATOM 5652 C CA  . VAL E 5 49  ? 364.762 367.368 458.195 1.00 62.85  ? 49  VAL C CA  1 
ATOM 5653 C C   . VAL E 5 49  ? 364.847 368.614 459.069 1.00 62.85  ? 49  VAL C C   1 
ATOM 5654 O O   . VAL E 5 49  ? 365.916 369.175 459.299 1.00 62.85  ? 49  VAL C O   1 
ATOM 5655 C CB  . VAL E 5 49  ? 364.470 366.115 459.032 1.00 62.85  ? 49  VAL C CB  1 
ATOM 5656 C CG1 . VAL E 5 49  ? 364.538 364.887 458.163 1.00 62.85  ? 49  VAL C CG1 1 
ATOM 5657 C CG2 . VAL E 5 49  ? 365.460 366.000 460.136 1.00 62.85  ? 49  VAL C CG2 1 
ATOM 5658 N N   . ASP E 5 50  ? 363.697 369.058 459.556 1.00 63.33  ? 50  ASP C N   1 
ATOM 5659 C CA  . ASP E 5 50  ? 363.614 370.281 460.340 1.00 63.33  ? 50  ASP C CA  1 
ATOM 5660 C C   . ASP E 5 50  ? 363.756 369.962 461.818 1.00 63.33  ? 50  ASP C C   1 
ATOM 5661 O O   . ASP E 5 50  ? 363.248 368.946 462.289 1.00 63.33  ? 50  ASP C O   1 
ATOM 5662 C CB  . ASP E 5 50  ? 362.292 371.001 460.092 1.00 63.33  ? 50  ASP C CB  1 
ATOM 5663 C CG  . ASP E 5 50  ? 362.105 371.399 458.641 1.00 63.33  ? 50  ASP C CG  1 
ATOM 5664 O OD1 . ASP E 5 50  ? 361.593 370.576 457.855 1.00 63.33  ? 50  ASP C OD1 1 
ATOM 5665 O OD2 . ASP E 5 50  ? 362.459 372.541 458.285 1.00 63.33  ? 50  ASP C OD2 1 
ATOM 5666 N N   . SER E 5 51  ? 364.454 370.824 462.547 1.00 55.95  ? 51  SER C N   1 
ATOM 5667 C CA  . SER E 5 51  ? 364.710 370.615 463.962 1.00 55.95  ? 51  SER C CA  1 
ATOM 5668 C C   . SER E 5 51  ? 364.640 371.938 464.695 1.00 55.95  ? 51  SER C C   1 
ATOM 5669 O O   . SER E 5 51  ? 365.015 372.976 464.155 1.00 55.95  ? 51  SER C O   1 
ATOM 5670 C CB  . SER E 5 51  ? 366.065 370.001 464.192 1.00 55.95  ? 51  SER C CB  1 
ATOM 5671 O OG  . SER E 5 51  ? 366.273 368.944 463.288 1.00 55.95  ? 51  SER C OG  1 
ATOM 5672 N N   . VAL E 5 52  ? 364.183 371.897 465.927 1.00 52.02  ? 52  VAL C N   1 
ATOM 5673 C CA  . VAL E 5 52  ? 363.942 373.120 466.676 1.00 52.02  ? 52  VAL C CA  1 
ATOM 5674 C C   . VAL E 5 52  ? 365.269 373.659 467.187 1.00 52.02  ? 52  VAL C C   1 
ATOM 5675 O O   . VAL E 5 52  ? 366.121 372.902 467.652 1.00 52.02  ? 52  VAL C O   1 
ATOM 5676 C CB  . VAL E 5 52  ? 362.954 372.853 467.821 1.00 52.02  ? 52  VAL C CB  1 
ATOM 5677 C CG1 . VAL E 5 52  ? 362.384 374.132 468.328 1.00 52.02  ? 52  VAL C CG1 1 
ATOM 5678 C CG2 . VAL E 5 52  ? 361.851 371.966 467.351 1.00 52.02  ? 52  VAL C CG2 1 
ATOM 5679 N N   . VAL E 5 53  ? 365.453 374.969 467.090 1.00 52.98  ? 53  VAL C N   1 
ATOM 5680 C CA  . VAL E 5 53  ? 366.707 375.628 467.439 1.00 52.98  ? 53  VAL C CA  1 
ATOM 5681 C C   . VAL E 5 53  ? 366.575 376.195 468.847 1.00 52.98  ? 53  VAL C C   1 
ATOM 5682 O O   . VAL E 5 53  ? 365.674 377.005 469.088 1.00 52.98  ? 53  VAL C O   1 
ATOM 5683 C CB  . VAL E 5 53  ? 367.049 376.741 466.444 1.00 52.98  ? 53  VAL C CB  1 
ATOM 5684 C CG1 . VAL E 5 53  ? 368.193 377.566 466.944 1.00 52.98  ? 53  VAL C CG1 1 
ATOM 5685 C CG2 . VAL E 5 53  ? 367.400 376.157 465.150 1.00 52.98  ? 53  VAL C CG2 1 
ATOM 5686 N N   . PRO E 5 54  ? 367.435 375.830 469.772 1.00 53.39  ? 54  PRO C N   1 
ATOM 5687 C CA  . PRO E 5 54  ? 367.378 376.433 471.102 1.00 53.39  ? 54  PRO C CA  1 
ATOM 5688 C C   . PRO E 5 54  ? 367.960 377.831 471.119 1.00 53.39  ? 54  PRO C C   1 
ATOM 5689 O O   . PRO E 5 54  ? 369.094 378.039 471.548 1.00 53.39  ? 54  PRO C O   1 
ATOM 5690 C CB  . PRO E 5 54  ? 368.206 375.469 471.950 1.00 53.39  ? 54  PRO C CB  1 
ATOM 5691 C CG  . PRO E 5 54  ? 369.133 374.851 471.008 1.00 53.39  ? 54  PRO C CG  1 
ATOM 5692 C CD  . PRO E 5 54  ? 368.474 374.800 469.676 1.00 53.39  ? 54  PRO C CD  1 
ATOM 5693 N N   . VAL E 5 55  ? 367.173 378.808 470.683 1.00 55.44  ? 55  VAL C N   1 
ATOM 5694 C CA  . VAL E 5 55  ? 367.663 380.154 470.437 1.00 55.44  ? 55  VAL C CA  1 
ATOM 5695 C C   . VAL E 5 55  ? 367.501 381.042 471.672 1.00 55.44  ? 55  VAL C C   1 
ATOM 5696 O O   . VAL E 5 55  ? 367.893 382.207 471.660 1.00 55.44  ? 55  VAL C O   1 
ATOM 5697 C CB  . VAL E 5 55  ? 366.953 380.728 469.195 1.00 55.44  ? 55  VAL C CB  1 
ATOM 5698 C CG1 . VAL E 5 55  ? 365.531 381.018 469.496 1.00 55.44  ? 55  VAL C CG1 1 
ATOM 5699 C CG2 . VAL E 5 55  ? 367.668 381.902 468.535 1.00 55.44  ? 55  VAL C CG2 1 
ATOM 5700 N N   . ASN E 5 56  ? 367.014 380.487 472.769 1.00 57.84  ? 56  ASN C N   1 
ATOM 5701 C CA  . ASN E 5 56  ? 366.709 381.225 473.989 1.00 57.84  ? 56  ASN C CA  1 
ATOM 5702 C C   . ASN E 5 56  ? 367.444 380.610 475.169 1.00 57.84  ? 56  ASN C C   1 
ATOM 5703 O O   . ASN E 5 56  ? 366.836 380.175 476.144 1.00 57.84  ? 56  ASN C O   1 
ATOM 5704 C CB  . ASN E 5 56  ? 365.207 381.258 474.235 1.00 57.84  ? 56  ASN C CB  1 
ATOM 5705 C CG  . ASN E 5 56  ? 364.806 382.263 475.285 1.00 57.84  ? 56  ASN C CG  1 
ATOM 5706 O OD1 . ASN E 5 56  ? 365.598 383.096 475.693 1.00 57.84  ? 56  ASN C OD1 1 
ATOM 5707 N ND2 . ASN E 5 56  ? 363.572 382.175 475.740 1.00 57.84  ? 56  ASN C ND2 1 
ATOM 5708 N N   . ASN E 5 57  ? 368.768 380.486 475.053 1.00 60.02  ? 57  ASN C N   1 
ATOM 5709 C CA  . ASN E 5 57  ? 369.588 379.822 476.062 1.00 60.02  ? 57  ASN C CA  1 
ATOM 5710 C C   . ASN E 5 57  ? 369.527 380.484 477.435 1.00 60.02  ? 57  ASN C C   1 
ATOM 5711 O O   . ASN E 5 57  ? 368.985 379.900 478.374 1.00 60.02  ? 57  ASN C O   1 
ATOM 5712 C CB  . ASN E 5 57  ? 371.046 379.783 475.618 1.00 60.02  ? 57  ASN C CB  1 
ATOM 5713 C CG  . ASN E 5 57  ? 371.216 379.354 474.192 1.00 60.02  ? 57  ASN C CG  1 
ATOM 5714 O OD1 . ASN E 5 57  ? 372.026 379.911 473.461 1.00 60.02  ? 57  ASN C OD1 1 
ATOM 5715 N ND2 . ASN E 5 57  ? 370.470 378.349 473.787 1.00 60.02  ? 57  ASN C ND2 1 
ATOM 5716 N N   . THR E 5 58  ? 370.065 381.698 477.553 1.00 65.76  ? 58  THR C N   1 
ATOM 5717 C CA  . THR E 5 58  ? 370.003 382.575 478.726 1.00 65.76  ? 58  THR C CA  1 
ATOM 5718 C C   . THR E 5 58  ? 370.322 381.960 480.085 1.00 65.76  ? 58  THR C C   1 
ATOM 5719 O O   . THR E 5 58  ? 369.842 382.470 481.100 1.00 65.76  ? 58  THR C O   1 
ATOM 5720 C CB  . THR E 5 58  ? 368.628 383.229 478.843 1.00 65.76  ? 58  THR C CB  1 
ATOM 5721 O OG1 . THR E 5 58  ? 367.643 382.235 479.138 1.00 65.76  ? 58  THR C OG1 1 
ATOM 5722 C CG2 . THR E 5 58  ? 368.269 383.941 477.564 1.00 65.76  ? 58  THR C CG2 1 
ATOM 5723 N N   . GLU E 5 59  ? 371.070 380.853 480.118 1.00 70.43  ? 59  GLU C N   1 
ATOM 5724 C CA  . GLU E 5 59  ? 371.733 380.309 481.307 1.00 70.43  ? 59  GLU C CA  1 
ATOM 5725 C C   . GLU E 5 59  ? 370.805 379.777 482.390 1.00 70.43  ? 59  GLU C C   1 
ATOM 5726 O O   . GLU E 5 59  ? 371.287 379.282 483.411 1.00 70.43  ? 59  GLU C O   1 
ATOM 5727 C CB  . GLU E 5 59  ? 372.680 381.353 481.918 1.00 70.43  ? 59  GLU C CB  1 
ATOM 5728 C CG  . GLU E 5 59  ? 373.870 381.686 481.032 1.00 70.43  ? 59  GLU C CG  1 
ATOM 5729 C CD  . GLU E 5 59  ? 374.739 382.782 481.582 1.00 70.43  ? 59  GLU C CD  1 
ATOM 5730 O OE1 . GLU E 5 59  ? 374.328 383.430 482.563 1.00 70.43  ? 59  GLU C OE1 1 
ATOM 5731 O OE2 . GLU E 5 59  ? 375.841 382.986 481.036 1.00 70.43  ? 59  GLU C OE2 1 
ATOM 5732 N N   . ASP E 5 60  ? 369.494 379.858 482.196 1.00 65.37  ? 60  ASP C N   1 
ATOM 5733 C CA  . ASP E 5 60  ? 368.553 379.204 483.088 1.00 65.37  ? 60  ASP C CA  1 
ATOM 5734 C C   . ASP E 5 60  ? 367.415 378.524 482.351 1.00 65.37  ? 60  ASP C C   1 
ATOM 5735 O O   . ASP E 5 60  ? 366.566 377.900 482.991 1.00 65.37  ? 60  ASP C O   1 
ATOM 5736 C CB  . ASP E 5 60  ? 367.991 380.197 484.108 1.00 65.37  ? 60  ASP C CB  1 
ATOM 5737 C CG  . ASP E 5 60  ? 367.520 381.471 483.494 1.00 65.37  ? 60  ASP C CG  1 
ATOM 5738 O OD1 . ASP E 5 60  ? 367.410 381.554 482.263 1.00 65.37  ? 60  ASP C OD1 1 
ATOM 5739 O OD2 . ASP E 5 60  ? 367.277 382.420 484.258 1.00 65.37  ? 60  ASP C OD2 1 
ATOM 5740 N N   . ASN E 5 61  ? 367.371 378.633 481.033 1.00 60.15  ? 61  ASN C N   1 
ATOM 5741 C CA  . ASN E 5 61  ? 366.383 377.958 480.225 1.00 60.15  ? 61  ASN C CA  1 
ATOM 5742 C C   . ASN E 5 61  ? 366.927 376.713 479.565 1.00 60.15  ? 61  ASN C C   1 
ATOM 5743 O O   . ASN E 5 61  ? 366.168 376.021 478.892 1.00 60.15  ? 61  ASN C O   1 
ATOM 5744 C CB  . ASN E 5 61  ? 365.849 378.900 479.149 1.00 60.15  ? 61  ASN C CB  1 
ATOM 5745 C CG  . ASN E 5 61  ? 365.280 380.157 479.724 1.00 60.15  ? 61  ASN C CG  1 
ATOM 5746 O OD1 . ASN E 5 61  ? 365.154 380.289 480.933 1.00 60.15  ? 61  ASN C OD1 1 
ATOM 5747 N ND2 . ASN E 5 61  ? 364.926 381.094 478.864 1.00 60.15  ? 61  ASN C ND2 1 
ATOM 5748 N N   . VAL E 5 62  ? 368.212 376.407 479.733 1.00 58.12  ? 62  VAL C N   1 
ATOM 5749 C CA  . VAL E 5 62  ? 368.792 375.303 478.979 1.00 58.12  ? 62  VAL C CA  1 
ATOM 5750 C C   . VAL E 5 62  ? 368.342 373.960 479.524 1.00 58.12  ? 62  VAL C C   1 
ATOM 5751 O O   . VAL E 5 62  ? 368.254 372.985 478.775 1.00 58.12  ? 62  VAL C O   1 
ATOM 5752 C CB  . VAL E 5 62  ? 370.319 375.410 478.952 1.00 58.12  ? 62  VAL C CB  1 
ATOM 5753 C CG1 . VAL E 5 62  ? 370.724 376.508 478.028 1.00 58.12  ? 62  VAL C CG1 1 
ATOM 5754 C CG2 . VAL E 5 62  ? 370.858 375.664 480.333 1.00 58.12  ? 62  VAL C CG2 1 
ATOM 5755 N N   . SER E 5 63  ? 368.057 373.875 480.813 1.00 58.93  ? 63  SER C N   1 
ATOM 5756 C CA  . SER E 5 63  ? 367.446 372.686 481.393 1.00 58.93  ? 63  SER C CA  1 
ATOM 5757 C C   . SER E 5 63  ? 365.943 372.845 481.470 1.00 58.93  ? 63  SER C C   1 
ATOM 5758 O O   . SER E 5 63  ? 365.351 372.720 482.533 1.00 58.93  ? 63  SER C O   1 
ATOM 5759 C CB  . SER E 5 63  ? 368.029 372.416 482.764 1.00 58.93  ? 63  SER C CB  1 
ATOM 5760 O OG  . SER E 5 63  ? 367.306 373.141 483.733 1.00 58.93  ? 63  SER C OG  1 
ATOM 5761 N N   . SER E 5 64  ? 365.317 373.136 480.338 1.00 55.89  ? 64  SER C N   1 
ATOM 5762 C CA  . SER E 5 64  ? 363.878 373.331 480.270 1.00 55.89  ? 64  SER C CA  1 
ATOM 5763 C C   . SER E 5 64  ? 363.431 373.168 478.829 1.00 55.89  ? 64  SER C C   1 
ATOM 5764 O O   . SER E 5 64  ? 364.243 372.985 477.922 1.00 55.89  ? 64  SER C O   1 
ATOM 5765 C CB  . SER E 5 64  ? 363.481 374.707 480.784 1.00 55.89  ? 64  SER C CB  1 
ATOM 5766 O OG  . SER E 5 64  ? 362.098 374.910 480.615 1.00 55.89  ? 64  SER C OG  1 
ATOM 5767 N N   . LEU E 5 65  ? 362.125 373.247 478.623 1.00 52.76  ? 65  LEU C N   1 
ATOM 5768 C CA  . LEU E 5 65  ? 361.560 373.395 477.294 1.00 52.76  ? 65  LEU C CA  1 
ATOM 5769 C C   . LEU E 5 65  ? 361.389 374.853 476.920 1.00 52.76  ? 65  LEU C C   1 
ATOM 5770 O O   . LEU E 5 65  ? 360.874 375.152 475.845 1.00 52.76  ? 65  LEU C O   1 
ATOM 5771 C CB  . LEU E 5 65  ? 360.222 372.671 477.203 1.00 52.76  ? 65  LEU C CB  1 
ATOM 5772 C CG  . LEU E 5 65  ? 360.240 371.234 476.704 1.00 52.76  ? 65  LEU C CG  1 
ATOM 5773 C CD1 . LEU E 5 65  ? 358.853 370.676 476.718 1.00 52.76  ? 65  LEU C CD1 1 
ATOM 5774 C CD2 . LEU E 5 65  ? 360.760 371.217 475.318 1.00 52.76  ? 65  LEU C CD2 1 
ATOM 5775 N N   . LYS E 5 66  ? 361.803 375.763 477.793 1.00 55.40  ? 66  LYS C N   1 
ATOM 5776 C CA  . LYS E 5 66  ? 361.766 377.192 477.539 1.00 55.40  ? 66  LYS C CA  1 
ATOM 5777 C C   . LYS E 5 66  ? 362.902 377.646 476.643 1.00 55.40  ? 66  LYS C C   1 
ATOM 5778 O O   . LYS E 5 66  ? 362.864 378.771 476.146 1.00 55.40  ? 66  LYS C O   1 
ATOM 5779 C CB  . LYS E 5 66  ? 361.814 377.947 478.870 1.00 55.40  ? 66  LYS C CB  1 
ATOM 5780 C CG  . LYS E 5 66  ? 361.240 379.341 478.856 1.00 55.40  ? 66  LYS C CG  1 
ATOM 5781 C CD  . LYS E 5 66  ? 359.751 379.335 479.067 1.00 55.40  ? 66  LYS C CD  1 
ATOM 5782 C CE  . LYS E 5 66  ? 359.213 380.751 479.129 1.00 55.40  ? 66  LYS C CE  1 
ATOM 5783 N NZ  . LYS E 5 66  ? 359.264 381.441 477.812 1.00 55.40  ? 66  LYS C NZ  1 
ATOM 5784 N N   . ALA E 5 67  ? 363.896 376.794 476.403 1.00 54.70  ? 67  ALA C N   1 
ATOM 5785 C CA  . ALA E 5 67  ? 365.012 377.161 475.546 1.00 54.70  ? 67  ALA C CA  1 
ATOM 5786 C C   . ALA E 5 67  ? 364.605 377.310 474.098 1.00 54.70  ? 67  ALA C C   1 
ATOM 5787 O O   . ALA E 5 67  ? 365.312 377.966 473.336 1.00 54.70  ? 67  ALA C O   1 
ATOM 5788 C CB  . ALA E 5 67  ? 366.119 376.123 475.633 1.00 54.70  ? 67  ALA C CB  1 
ATOM 5789 N N   . TYR E 5 68  ? 363.491 376.725 473.701 1.00 52.97  ? 68  TYR C N   1 
ATOM 5790 C CA  . TYR E 5 68  ? 363.067 376.762 472.320 1.00 52.97  ? 68  TYR C CA  1 
ATOM 5791 C C   . TYR E 5 68  ? 362.112 377.901 472.013 1.00 52.97  ? 68  TYR C C   1 
ATOM 5792 O O   . TYR E 5 68  ? 361.832 378.143 470.840 1.00 52.97  ? 68  TYR C O   1 
ATOM 5793 C CB  . TYR E 5 68  ? 362.411 375.434 471.956 1.00 52.97  ? 68  TYR C CB  1 
ATOM 5794 C CG  . TYR E 5 68  ? 363.303 374.250 472.191 1.00 52.97  ? 68  TYR C CG  1 
ATOM 5795 C CD1 . TYR E 5 68  ? 364.360 373.988 471.348 1.00 52.97  ? 68  TYR C CD1 1 
ATOM 5796 C CD2 . TYR E 5 68  ? 363.094 373.402 473.255 1.00 52.97  ? 68  TYR C CD2 1 
ATOM 5797 C CE1 . TYR E 5 68  ? 365.173 372.920 471.550 1.00 52.97  ? 68  TYR C CE1 1 
ATOM 5798 C CE2 . TYR E 5 68  ? 363.911 372.326 473.466 1.00 52.97  ? 68  TYR C CE2 1 
ATOM 5799 C CZ  . TYR E 5 68  ? 364.944 372.093 472.607 1.00 52.97  ? 68  TYR C CZ  1 
ATOM 5800 O OH  . TYR E 5 68  ? 365.764 371.021 472.806 1.00 52.97  ? 68  TYR C OH  1 
ATOM 5801 N N   . GLN E 5 69  ? 361.626 378.613 473.020 1.00 54.23  ? 69  GLN C N   1 
ATOM 5802 C CA  . GLN E 5 69  ? 360.565 379.591 472.853 1.00 54.23  ? 69  GLN C CA  1 
ATOM 5803 C C   . GLN E 5 69  ? 361.106 381.005 472.963 1.00 54.23  ? 69  GLN C C   1 
ATOM 5804 O O   . GLN E 5 69  ? 361.767 381.352 473.942 1.00 54.23  ? 69  GLN C O   1 
ATOM 5805 C CB  . GLN E 5 69  ? 359.481 379.382 473.896 1.00 54.23  ? 69  GLN C CB  1 
ATOM 5806 C CG  . GLN E 5 69  ? 359.006 377.972 473.958 1.00 54.23  ? 69  GLN C CG  1 
ATOM 5807 C CD  . GLN E 5 69  ? 358.268 377.680 475.223 1.00 54.23  ? 69  GLN C CD  1 
ATOM 5808 O OE1 . GLN E 5 69  ? 357.722 378.576 475.852 1.00 54.23  ? 69  GLN C OE1 1 
ATOM 5809 N NE2 . GLN E 5 69  ? 358.243 376.420 475.611 1.00 54.23  ? 69  GLN C NE2 1 
ATOM 5810 N N   . ILE E 5 70  ? 360.797 381.822 471.966 1.00 57.13  ? 70  ILE C N   1 
ATOM 5811 C CA  . ILE E 5 70  ? 361.199 383.224 471.929 1.00 57.13  ? 70  ILE C CA  1 
ATOM 5812 C C   . ILE E 5 70  ? 360.055 384.050 472.501 1.00 57.13  ? 70  ILE C C   1 
ATOM 5813 O O   . ILE E 5 70  ? 358.935 383.963 471.986 1.00 57.13  ? 70  ILE C O   1 
ATOM 5814 C CB  . ILE E 5 70  ? 361.529 383.670 470.502 1.00 57.13  ? 70  ILE C CB  1 
ATOM 5815 C CG1 . ILE E 5 70  ? 362.237 382.548 469.767 1.00 57.13  ? 70  ILE C CG1 1 
ATOM 5816 C CG2 . ILE E 5 70  ? 362.407 384.874 470.526 1.00 57.13  ? 70  ILE C CG2 1 
ATOM 5817 C CD1 . ILE E 5 70  ? 362.456 382.819 468.322 1.00 57.13  ? 70  ILE C CD1 1 
ATOM 5818 N N   . PRO E 5 71  ? 360.282 384.852 473.535 1.00 59.48  ? 71  PRO C N   1 
ATOM 5819 C CA  . PRO E 5 71  ? 359.181 385.611 474.129 1.00 59.48  ? 71  PRO C CA  1 
ATOM 5820 C C   . PRO E 5 71  ? 358.808 386.796 473.255 1.00 59.48  ? 71  PRO C C   1 
ATOM 5821 O O   . PRO E 5 71  ? 359.671 387.557 472.817 1.00 59.48  ? 71  PRO C O   1 
ATOM 5822 C CB  . PRO E 5 71  ? 359.749 386.068 475.476 1.00 59.48  ? 71  PRO C CB  1 
ATOM 5823 C CG  . PRO E 5 71  ? 361.069 385.404 475.610 1.00 59.48  ? 71  PRO C CG  1 
ATOM 5824 C CD  . PRO E 5 71  ? 361.539 385.101 474.242 1.00 59.48  ? 71  PRO C CD  1 
ATOM 5825 N N   . VAL E 5 72  ? 357.515 386.946 473.000 1.00 63.93  ? 72  VAL C N   1 
ATOM 5826 C CA  . VAL E 5 72  ? 356.985 388.071 472.244 1.00 63.93  ? 72  VAL C CA  1 
ATOM 5827 C C   . VAL E 5 72  ? 355.858 388.678 473.059 1.00 63.93  ? 72  VAL C C   1 
ATOM 5828 O O   . VAL E 5 72  ? 354.880 387.994 473.370 1.00 63.93  ? 72  VAL C O   1 
ATOM 5829 C CB  . VAL E 5 72  ? 356.482 387.646 470.859 1.00 63.93  ? 72  VAL C CB  1 
ATOM 5830 C CG1 . VAL E 5 72  ? 355.654 388.732 470.242 1.00 63.93  ? 72  VAL C CG1 1 
ATOM 5831 C CG2 . VAL E 5 72  ? 357.637 387.339 469.971 1.00 63.93  ? 72  VAL C CG2 1 
ATOM 5832 N N   . GLN E 5 73  ? 355.992 389.951 473.412 1.00 70.20  ? 73  GLN C N   1 
ATOM 5833 C CA  . GLN E 5 73  ? 354.959 390.635 474.165 1.00 70.20  ? 73  GLN C CA  1 
ATOM 5834 C C   . GLN E 5 73  ? 354.697 391.993 473.545 1.00 70.20  ? 73  GLN C C   1 
ATOM 5835 O O   . GLN E 5 73  ? 355.488 392.498 472.751 1.00 70.20  ? 73  GLN C O   1 
ATOM 5836 C CB  . GLN E 5 73  ? 355.337 390.802 475.634 1.00 70.20  ? 73  GLN C CB  1 
ATOM 5837 C CG  . GLN E 5 73  ? 356.502 391.721 475.865 1.00 70.20  ? 73  GLN C CG  1 
ATOM 5838 C CD  . GLN E 5 73  ? 357.782 390.965 476.098 1.00 70.20  ? 73  GLN C CD  1 
ATOM 5839 O OE1 . GLN E 5 73  ? 357.858 389.766 475.851 1.00 70.20  ? 73  GLN C OE1 1 
ATOM 5840 N NE2 . GLN E 5 73  ? 358.798 391.659 476.587 1.00 70.20  ? 73  GLN C NE2 1 
ATOM 5841 N N   . SER E 5 74  ? 353.567 392.581 473.924 1.00 77.54  ? 74  SER C N   1 
ATOM 5842 C CA  . SER E 5 74  ? 353.133 393.866 473.386 1.00 77.54  ? 74  SER C CA  1 
ATOM 5843 C C   . SER E 5 74  ? 353.666 394.972 474.284 1.00 77.54  ? 74  SER C C   1 
ATOM 5844 O O   . SER E 5 74  ? 353.050 395.323 475.291 1.00 77.54  ? 74  SER C O   1 
ATOM 5845 C CB  . SER E 5 74  ? 351.616 393.921 473.284 1.00 77.54  ? 74  SER C CB  1 
ATOM 5846 O OG  . SER E 5 74  ? 351.060 394.436 474.474 1.00 77.54  ? 74  SER C OG  1 
ATOM 5847 N N   . ASN E 5 75  ? 354.811 395.527 473.915 1.00 81.18  ? 75  ASN C N   1 
ATOM 5848 C CA  . ASN E 5 75  ? 355.449 396.589 474.673 1.00 81.18  ? 75  ASN C CA  1 
ATOM 5849 C C   . ASN E 5 75  ? 354.947 397.946 474.184 1.00 81.18  ? 75  ASN C C   1 
ATOM 5850 O O   . ASN E 5 75  ? 353.965 398.040 473.444 1.00 81.18  ? 75  ASN C O   1 
ATOM 5851 C CB  . ASN E 5 75  ? 356.962 396.457 474.567 1.00 81.18  ? 75  ASN C CB  1 
ATOM 5852 C CG  . ASN E 5 75  ? 357.414 396.165 473.162 1.00 81.18  ? 75  ASN C CG  1 
ATOM 5853 O OD1 . ASN E 5 75  ? 356.615 396.159 472.232 1.00 81.18  ? 75  ASN C OD1 1 
ATOM 5854 N ND2 . ASN E 5 75  ? 358.701 395.909 473.000 1.00 81.18  ? 75  ASN C ND2 1 
ATOM 5855 N N   . SER E 5 76  ? 355.620 399.018 474.600 1.00 88.14  ? 76  SER C N   1 
ATOM 5856 C CA  . SER E 5 76  ? 355.161 400.372 474.330 1.00 88.14  ? 76  SER C CA  1 
ATOM 5857 C C   . SER E 5 76  ? 356.058 401.161 473.388 1.00 88.14  ? 76  SER C C   1 
ATOM 5858 O O   . SER E 5 76  ? 355.663 402.250 472.961 1.00 88.14  ? 76  SER C O   1 
ATOM 5859 C CB  . SER E 5 76  ? 355.018 401.154 475.641 1.00 88.14  ? 76  SER C CB  1 
ATOM 5860 O OG  . SER E 5 76  ? 355.085 402.546 475.395 1.00 88.14  ? 76  SER C OG  1 
ATOM 5861 N N   . ASP E 5 77  ? 357.246 400.664 473.068 1.00 89.25  ? 77  ASP C N   1 
ATOM 5862 C CA  . ASP E 5 77  ? 358.148 401.355 472.158 1.00 89.25  ? 77  ASP C CA  1 
ATOM 5863 C C   . ASP E 5 77  ? 358.160 400.674 470.797 1.00 89.25  ? 77  ASP C C   1 
ATOM 5864 O O   . ASP E 5 77  ? 358.387 399.467 470.691 1.00 89.25  ? 77  ASP C O   1 
ATOM 5865 C CB  . ASP E 5 77  ? 359.562 401.404 472.736 1.00 89.25  ? 77  ASP C CB  1 
ATOM 5866 C CG  . ASP E 5 77  ? 359.904 400.170 473.542 1.00 89.25  ? 77  ASP C CG  1 
ATOM 5867 O OD1 . ASP E 5 77  ? 359.135 399.191 473.489 1.00 89.25  ? 77  ASP C OD1 1 
ATOM 5868 O OD2 . ASP E 5 77  ? 360.926 400.187 474.256 1.00 89.25  ? 77  ASP C OD2 1 
ATOM 5869 N N   . ASN E 5 78  ? 357.916 401.459 469.756 1.00 85.96  ? 78  ASN C N   1 
ATOM 5870 C CA  . ASN E 5 78  ? 357.842 400.952 468.393 1.00 85.96  ? 78  ASN C CA  1 
ATOM 5871 C C   . ASN E 5 78  ? 359.261 400.802 467.865 1.00 85.96  ? 78  ASN C C   1 
ATOM 5872 O O   . ASN E 5 78  ? 360.000 401.785 467.760 1.00 85.96  ? 78  ASN C O   1 
ATOM 5873 C CB  . ASN E 5 78  ? 357.017 401.883 467.511 1.00 85.96  ? 78  ASN C CB  1 
ATOM 5874 C CG  . ASN E 5 78  ? 356.573 401.227 466.218 1.00 85.96  ? 78  ASN C CG  1 
ATOM 5875 O OD1 . ASN E 5 78  ? 357.388 400.744 465.432 1.00 85.96  ? 78  ASN C OD1 1 
ATOM 5876 N ND2 . ASN E 5 78  ? 355.265 401.199 465.996 1.00 85.96  ? 78  ASN C ND2 1 
ATOM 5877 N N   . GLY E 5 79  ? 359.641 399.569 467.550 1.00 77.63  ? 79  GLY C N   1 
ATOM 5878 C CA  . GLY E 5 79  ? 360.952 399.279 467.016 1.00 77.63  ? 79  GLY C CA  1 
ATOM 5879 C C   . GLY E 5 79  ? 361.863 398.756 468.099 1.00 77.63  ? 79  GLY C C   1 
ATOM 5880 O O   . GLY E 5 79  ? 362.429 399.530 468.871 1.00 77.63  ? 79  GLY C O   1 
ATOM 5881 N N   . LYS E 5 80  ? 362.009 397.440 468.164 1.00 70.22  ? 80  LYS C N   1 
ATOM 5882 C CA  . LYS E 5 80  ? 362.865 396.790 469.141 1.00 70.22  ? 80  LYS C CA  1 
ATOM 5883 C C   . LYS E 5 80  ? 363.293 395.460 468.562 1.00 70.22  ? 80  LYS C C   1 
ATOM 5884 O O   . LYS E 5 80  ? 362.730 394.987 467.576 1.00 70.22  ? 80  LYS C O   1 
ATOM 5885 C CB  . LYS E 5 80  ? 362.161 396.581 470.480 1.00 70.22  ? 80  LYS C CB  1 
ATOM 5886 C CG  . LYS E 5 80  ? 362.511 397.601 471.527 1.00 70.22  ? 80  LYS C CG  1 
ATOM 5887 C CD  . LYS E 5 80  ? 361.813 397.282 472.824 1.00 70.22  ? 80  LYS C CD  1 
ATOM 5888 C CE  . LYS E 5 80  ? 362.321 395.987 473.425 1.00 70.22  ? 80  LYS C CE  1 
ATOM 5889 N NZ  . LYS E 5 80  ? 361.686 395.688 474.737 1.00 70.22  ? 80  LYS C NZ  1 
ATOM 5890 N N   . GLN E 5 81  ? 364.287 394.857 469.190 1.00 63.16  ? 81  GLN C N   1 
ATOM 5891 C CA  . GLN E 5 81  ? 364.805 393.583 468.729 1.00 63.16  ? 81  GLN C CA  1 
ATOM 5892 C C   . GLN E 5 81  ? 364.065 392.461 469.436 1.00 63.16  ? 81  GLN C C   1 
ATOM 5893 O O   . GLN E 5 81  ? 363.894 392.499 470.657 1.00 63.16  ? 81  GLN C O   1 
ATOM 5894 C CB  . GLN E 5 81  ? 366.300 393.488 468.986 1.00 63.16  ? 81  GLN C CB  1 
ATOM 5895 C CG  . GLN E 5 81  ? 367.005 392.610 468.010 1.00 63.16  ? 81  GLN C CG  1 
ATOM 5896 C CD  . GLN E 5 81  ? 368.483 392.618 468.221 1.00 63.16  ? 81  GLN C CD  1 
ATOM 5897 O OE1 . GLN E 5 81  ? 368.973 393.165 469.199 1.00 63.16  ? 81  GLN C OE1 1 
ATOM 5898 N NE2 . GLN E 5 81  ? 369.212 392.025 467.300 1.00 63.16  ? 81  GLN C NE2 1 
ATOM 5899 N N   . VAL E 5 82  ? 363.609 391.476 468.669 1.00 59.41  ? 82  VAL C N   1 
ATOM 5900 C CA  . VAL E 5 82  ? 363.042 390.280 469.273 1.00 59.41  ? 82  VAL C CA  1 
ATOM 5901 C C   . VAL E 5 82  ? 364.145 389.323 469.683 1.00 59.41  ? 82  VAL C C   1 
ATOM 5902 O O   . VAL E 5 82  ? 364.286 388.986 470.861 1.00 59.41  ? 82  VAL C O   1 
ATOM 5903 C CB  . VAL E 5 82  ? 362.051 389.611 468.311 1.00 59.41  ? 82  VAL C CB  1 
ATOM 5904 C CG1 . VAL E 5 82  ? 361.520 388.355 468.927 1.00 59.41  ? 82  VAL C CG1 1 
ATOM 5905 C CG2 . VAL E 5 82  ? 360.928 390.538 468.001 1.00 59.41  ? 82  VAL C CG2 1 
ATOM 5906 N N   . PHE E 5 83  ? 364.950 388.880 468.726 1.00 57.82  ? 83  PHE C N   1 
ATOM 5907 C CA  . PHE E 5 83  ? 366.100 388.044 469.013 1.00 57.82  ? 83  PHE C CA  1 
ATOM 5908 C C   . PHE E 5 83  ? 367.216 388.419 468.053 1.00 57.82  ? 83  PHE C C   1 
ATOM 5909 O O   . PHE E 5 83  ? 367.093 389.363 467.271 1.00 57.82  ? 83  PHE C O   1 
ATOM 5910 C CB  . PHE E 5 83  ? 365.740 386.559 468.921 1.00 57.82  ? 83  PHE C CB  1 
ATOM 5911 C CG  . PHE E 5 83  ? 365.297 386.108 467.562 1.00 57.82  ? 83  PHE C CG  1 
ATOM 5912 C CD1 . PHE E 5 83  ? 363.970 386.159 467.210 1.00 57.82  ? 83  PHE C CD1 1 
ATOM 5913 C CD2 . PHE E 5 83  ? 366.197 385.572 466.662 1.00 57.82  ? 83  PHE C CD2 1 
ATOM 5914 C CE1 . PHE E 5 83  ? 363.558 385.722 465.986 1.00 57.82  ? 83  PHE C CE1 1 
ATOM 5915 C CE2 . PHE E 5 83  ? 365.787 385.148 465.433 1.00 57.82  ? 83  PHE C CE2 1 
ATOM 5916 C CZ  . PHE E 5 83  ? 364.469 385.226 465.097 1.00 57.82  ? 83  PHE C CZ  1 
ATOM 5917 N N   . GLY E 5 84  ? 368.306 387.669 468.107 1.00 58.11  ? 84  GLY C N   1 
ATOM 5918 C CA  . GLY E 5 84  ? 369.391 387.833 467.167 1.00 58.11  ? 84  GLY C CA  1 
ATOM 5919 C C   . GLY E 5 84  ? 370.516 386.877 467.478 1.00 58.11  ? 84  GLY C C   1 
ATOM 5920 O O   . GLY E 5 84  ? 370.904 386.740 468.638 1.00 58.11  ? 84  GLY C O   1 
ATOM 5921 N N   . PHE E 5 85  ? 371.053 386.199 466.466 1.00 56.88  ? 85  PHE C N   1 
ATOM 5922 C CA  . PHE E 5 85  ? 372.107 385.252 466.740 1.00 56.88  ? 85  PHE C CA  1 
ATOM 5923 C C   . PHE E 5 85  ? 373.075 385.192 465.573 1.00 56.88  ? 85  PHE C C   1 
ATOM 5924 O O   . PHE E 5 85  ? 372.635 385.218 464.420 1.00 56.88  ? 85  PHE C O   1 
ATOM 5925 C CB  . PHE E 5 85  ? 371.554 383.854 467.046 1.00 56.88  ? 85  PHE C CB  1 
ATOM 5926 C CG  . PHE E 5 85  ? 370.762 383.225 465.937 1.00 56.88  ? 85  PHE C CG  1 
ATOM 5927 C CD1 . PHE E 5 85  ? 369.420 383.485 465.798 1.00 56.88  ? 85  PHE C CD1 1 
ATOM 5928 C CD2 . PHE E 5 85  ? 371.345 382.314 465.086 1.00 56.88  ? 85  PHE C CD2 1 
ATOM 5929 C CE1 . PHE E 5 85  ? 368.687 382.885 464.804 1.00 56.88  ? 85  PHE C CE1 1 
ATOM 5930 C CE2 . PHE E 5 85  ? 370.616 381.717 464.090 1.00 56.88  ? 85  PHE C CE2 1 
ATOM 5931 C CZ  . PHE E 5 85  ? 369.287 382.003 463.951 1.00 56.88  ? 85  PHE C CZ  1 
ATOM 5932 N N   . PRO E 5 86  ? 374.375 385.120 465.831 1.00 57.92  ? 86  PRO C N   1 
ATOM 5933 C CA  . PRO E 5 86  ? 375.352 385.112 464.744 1.00 57.92  ? 86  PRO C CA  1 
ATOM 5934 C C   . PRO E 5 86  ? 375.420 383.751 464.074 1.00 57.92  ? 86  PRO C C   1 
ATOM 5935 O O   . PRO E 5 86  ? 374.982 382.741 464.615 1.00 57.92  ? 86  PRO C O   1 
ATOM 5936 C CB  . PRO E 5 86  ? 376.656 385.428 465.464 1.00 57.92  ? 86  PRO C CB  1 
ATOM 5937 C CG  . PRO E 5 86  ? 376.469 384.827 466.781 1.00 57.92  ? 86  PRO C CG  1 
ATOM 5938 C CD  . PRO E 5 86  ? 375.037 385.030 467.140 1.00 57.92  ? 86  PRO C CD  1 
ATOM 5939 N N   . LEU E 5 87  ? 375.993 383.738 462.876 1.00 59.36  ? 87  LEU C N   1 
ATOM 5940 C CA  . LEU E 5 87  ? 376.199 382.498 462.145 1.00 59.36  ? 87  LEU C CA  1 
ATOM 5941 C C   . LEU E 5 87  ? 377.641 382.012 462.219 1.00 59.36  ? 87  LEU C C   1 
ATOM 5942 O O   . LEU E 5 87  ? 378.074 381.245 461.360 1.00 59.36  ? 87  LEU C O   1 
ATOM 5943 C CB  . LEU E 5 87  ? 375.776 382.661 460.690 1.00 59.36  ? 87  LEU C CB  1 
ATOM 5944 C CG  . LEU E 5 87  ? 374.290 382.846 460.427 1.00 59.36  ? 87  LEU C CG  1 
ATOM 5945 C CD1 . LEU E 5 87  ? 374.046 383.005 458.955 1.00 59.36  ? 87  LEU C CD1 1 
ATOM 5946 C CD2 . LEU E 5 87  ? 373.517 381.671 460.951 1.00 59.36  ? 87  LEU C CD2 1 
ATOM 5947 N N   . GLN E 5 88  ? 378.388 382.441 463.223 1.00 65.38  ? 88  GLN C N   1 
ATOM 5948 C CA  . GLN E 5 88  ? 379.768 382.017 463.396 1.00 65.38  ? 88  GLN C CA  1 
ATOM 5949 C C   . GLN E 5 88  ? 379.804 380.571 463.866 1.00 65.38  ? 88  GLN C C   1 
ATOM 5950 O O   . GLN E 5 88  ? 379.175 380.249 464.880 1.00 65.38  ? 88  GLN C O   1 
ATOM 5951 C CB  . GLN E 5 88  ? 380.465 382.920 464.404 1.00 65.38  ? 88  GLN C CB  1 
ATOM 5952 C CG  . GLN E 5 88  ? 381.918 382.584 464.671 1.00 65.38  ? 88  GLN C CG  1 
ATOM 5953 C CD  . GLN E 5 88  ? 382.811 382.867 463.494 1.00 65.38  ? 88  GLN C CD  1 
ATOM 5954 O OE1 . GLN E 5 88  ? 382.596 383.820 462.755 1.00 65.38  ? 88  GLN C OE1 1 
ATOM 5955 N NE2 . GLN E 5 88  ? 383.827 382.040 463.313 1.00 65.38  ? 88  GLN C NE2 1 
ATOM 5956 N N   . PRO E 5 89  ? 380.525 379.680 463.186 1.00 62.39  ? 89  PRO C N   1 
ATOM 5957 C CA  . PRO E 5 89  ? 380.383 378.245 463.452 1.00 62.39  ? 89  PRO C CA  1 
ATOM 5958 C C   . PRO E 5 89  ? 381.237 377.798 464.627 1.00 62.39  ? 89  PRO C C   1 
ATOM 5959 O O   . PRO E 5 89  ? 382.326 378.321 464.855 1.00 62.39  ? 89  PRO C O   1 
ATOM 5960 C CB  . PRO E 5 89  ? 380.851 377.598 462.145 1.00 62.39  ? 89  PRO C CB  1 
ATOM 5961 C CG  . PRO E 5 89  ? 381.102 378.724 461.203 1.00 62.39  ? 89  PRO C CG  1 
ATOM 5962 C CD  . PRO E 5 89  ? 381.393 379.910 462.032 1.00 62.39  ? 89  PRO C CD  1 
ATOM 5963 N N   . GLY E 5 90  ? 380.722 376.830 465.383 1.00 67.55  ? 90  GLY C N   1 
ATOM 5964 C CA  . GLY E 5 90  ? 381.500 376.101 466.358 1.00 67.55  ? 90  GLY C CA  1 
ATOM 5965 C C   . GLY E 5 90  ? 381.714 376.788 467.681 1.00 67.55  ? 90  GLY C C   1 
ATOM 5966 O O   . GLY E 5 90  ? 381.601 376.132 468.724 1.00 67.55  ? 90  GLY C O   1 
ATOM 5967 N N   . ALA E 5 91  ? 382.004 378.086 467.686 1.00 76.95  ? 91  ALA C N   1 
ATOM 5968 C CA  . ALA E 5 91  ? 382.259 378.829 468.919 1.00 76.95  ? 91  ALA C CA  1 
ATOM 5969 C C   . ALA E 5 91  ? 380.934 379.064 469.642 1.00 76.95  ? 91  ALA C C   1 
ATOM 5970 O O   . ALA E 5 91  ? 380.399 380.176 469.676 1.00 76.95  ? 91  ALA C O   1 
ATOM 5971 C CB  . ALA E 5 91  ? 382.972 380.141 468.617 1.00 76.95  ? 91  ALA C CB  1 
ATOM 5972 N N   . ASN E 5 92  ? 380.436 377.981 470.258 1.00 72.64  ? 92  ASN C N   1 
ATOM 5973 C CA  . ASN E 5 92  ? 379.203 377.876 471.052 1.00 72.64  ? 92  ASN C CA  1 
ATOM 5974 C C   . ASN E 5 92  ? 377.999 378.603 470.444 1.00 72.64  ? 92  ASN C C   1 
ATOM 5975 O O   . ASN E 5 92  ? 377.280 379.314 471.145 1.00 72.64  ? 92  ASN C O   1 
ATOM 5976 C CB  . ASN E 5 92  ? 379.428 378.307 472.515 1.00 72.64  ? 92  ASN C CB  1 
ATOM 5977 C CG  . ASN E 5 92  ? 379.954 379.722 472.666 1.00 72.64  ? 92  ASN C CG  1 
ATOM 5978 O OD1 . ASN E 5 92  ? 379.190 380.677 472.761 1.00 72.64  ? 92  ASN C OD1 1 
ATOM 5979 N ND2 . ASN E 5 92  ? 381.269 379.859 472.699 1.00 72.64  ? 92  ASN C ND2 1 
ATOM 5980 N N   . ASN E 5 93  ? 377.717 378.420 469.158 1.00 64.34  ? 93  ASN C N   1 
ATOM 5981 C CA  . ASN E 5 93  ? 376.505 379.008 468.604 1.00 64.34  ? 93  ASN C CA  1 
ATOM 5982 C C   . ASN E 5 93  ? 375.294 378.130 468.914 1.00 64.34  ? 93  ASN C C   1 
ATOM 5983 O O   . ASN E 5 93  ? 375.382 377.126 469.622 1.00 64.34  ? 93  ASN C O   1 
ATOM 5984 C CB  . ASN E 5 93  ? 376.634 379.263 467.111 1.00 64.34  ? 93  ASN C CB  1 
ATOM 5985 C CG  . ASN E 5 93  ? 376.935 378.034 466.339 1.00 64.34  ? 93  ASN C CG  1 
ATOM 5986 O OD1 . ASN E 5 93  ? 377.236 376.989 466.902 1.00 64.34  ? 93  ASN C OD1 1 
ATOM 5987 N ND2 . ASN E 5 93  ? 376.795 378.125 465.028 1.00 64.34  ? 93  ASN C ND2 1 
ATOM 5988 N N   . VAL E 5 94  ? 374.140 378.509 468.373 1.00 57.35  ? 94  VAL C N   1 
ATOM 5989 C CA  . VAL E 5 94  ? 372.893 377.850 468.728 1.00 57.35  ? 94  VAL C CA  1 
ATOM 5990 C C   . VAL E 5 94  ? 372.492 376.769 467.738 1.00 57.35  ? 94  VAL C C   1 
ATOM 5991 O O   . VAL E 5 94  ? 371.637 375.938 468.061 1.00 57.35  ? 94  VAL C O   1 
ATOM 5992 C CB  . VAL E 5 94  ? 371.769 378.886 468.865 1.00 57.35  ? 94  VAL C CB  1 
ATOM 5993 C CG1 . VAL E 5 94  ? 372.152 379.905 469.884 1.00 57.35  ? 94  VAL C CG1 1 
ATOM 5994 C CG2 . VAL E 5 94  ? 371.506 379.559 467.555 1.00 57.35  ? 94  VAL C CG2 1 
ATOM 5995 N N   . LEU E 5 95  ? 373.092 376.739 466.551 1.00 56.29  ? 95  LEU C N   1 
ATOM 5996 C CA  . LEU E 5 95  ? 372.837 375.684 465.587 1.00 56.29  ? 95  LEU C CA  1 
ATOM 5997 C C   . LEU E 5 95  ? 373.789 374.526 465.755 1.00 56.29  ? 95  LEU C C   1 
ATOM 5998 O O   . LEU E 5 95  ? 374.061 373.813 464.790 1.00 56.29  ? 95  LEU C O   1 
ATOM 5999 C CB  . LEU E 5 95  ? 372.946 376.214 464.161 1.00 56.29  ? 95  LEU C CB  1 
ATOM 6000 C CG  . LEU E 5 95  ? 372.216 377.477 463.740 1.00 56.29  ? 95  LEU C CG  1 
ATOM 6001 C CD1 . LEU E 5 95  ? 372.293 377.609 462.249 1.00 56.29  ? 95  LEU C CD1 1 
ATOM 6002 C CD2 . LEU E 5 95  ? 370.792 377.428 464.169 1.00 56.29  ? 95  LEU C CD2 1 
ATOM 6003 N N   . ASN E 5 96  ? 374.316 374.332 466.954 1.00 59.39  ? 96  ASN C N   1 
ATOM 6004 C CA  . ASN E 5 96  ? 375.442 373.436 467.132 1.00 59.39  ? 96  ASN C CA  1 
ATOM 6005 C C   . ASN E 5 96  ? 374.968 372.040 467.488 1.00 59.39  ? 96  ASN C C   1 
ATOM 6006 O O   . ASN E 5 96  ? 375.366 371.058 466.859 1.00 59.39  ? 96  ASN C O   1 
ATOM 6007 C CB  . ASN E 5 96  ? 376.353 373.983 468.219 1.00 59.39  ? 96  ASN C CB  1 
ATOM 6008 C CG  . ASN E 5 96  ? 377.762 373.580 468.025 1.00 59.39  ? 96  ASN C CG  1 
ATOM 6009 O OD1 . ASN E 5 96  ? 378.113 373.021 466.998 1.00 59.39  ? 96  ASN C OD1 1 
ATOM 6010 N ND2 . ASN E 5 96  ? 378.592 373.837 469.017 1.00 59.39  ? 96  ASN C ND2 1 
ATOM 6011 N N   . ARG E 5 97  ? 374.111 371.937 468.497 1.00 59.63  ? 97  ARG C N   1 
ATOM 6012 C CA  . ARG E 5 97  ? 373.586 370.661 468.947 1.00 59.63  ? 97  ARG C CA  1 
ATOM 6013 C C   . ARG E 5 97  ? 372.357 370.228 468.176 1.00 59.63  ? 97  ARG C C   1 
ATOM 6014 O O   . ARG E 5 97  ? 371.767 369.204 468.513 1.00 59.63  ? 97  ARG C O   1 
ATOM 6015 C CB  . ARG E 5 97  ? 373.235 370.718 470.431 1.00 59.63  ? 97  ARG C CB  1 
ATOM 6016 C CG  . ARG E 5 97  ? 374.307 371.285 471.336 1.00 59.63  ? 97  ARG C CG  1 
ATOM 6017 C CD  . ARG E 5 97  ? 375.603 370.539 471.206 1.00 59.63  ? 97  ARG C CD  1 
ATOM 6018 N NE  . ARG E 5 97  ? 375.446 369.115 471.459 1.00 59.63  ? 97  ARG C NE  1 
ATOM 6019 C CZ  . ARG E 5 97  ? 375.883 368.502 472.549 1.00 59.63  ? 97  ARG C CZ  1 
ATOM 6020 N NH1 . ARG E 5 97  ? 376.501 369.189 473.493 1.00 59.63  ? 97  ARG C NH1 1 
ATOM 6021 N NH2 . ARG E 5 97  ? 375.710 367.200 472.692 1.00 59.63  ? 97  ARG C NH2 1 
ATOM 6022 N N   . THR E 5 98  ? 371.946 370.976 467.164 1.00 56.61  ? 98  THR C N   1 
ATOM 6023 C CA  . THR E 5 98  ? 370.772 370.583 466.414 1.00 56.61  ? 98  THR C CA  1 
ATOM 6024 C C   . THR E 5 98  ? 371.115 369.439 465.475 1.00 56.61  ? 98  THR C C   1 
ATOM 6025 O O   . THR E 5 98  ? 372.268 369.049 465.323 1.00 56.61  ? 98  THR C O   1 
ATOM 6026 C CB  . THR E 5 98  ? 370.201 371.761 465.635 1.00 56.61  ? 98  THR C CB  1 
ATOM 6027 O OG1 . THR E 5 98  ? 369.044 371.327 464.925 1.00 56.61  ? 98  THR C OG1 1 
ATOM 6028 C CG2 . THR E 5 98  ? 371.183 372.253 464.643 1.00 56.61  ? 98  THR C CG2 1 
ATOM 6029 N N   . LEU E 5 99  ? 370.086 368.896 464.840 1.00 54.00  ? 99  LEU C N   1 
ATOM 6030 C CA  . LEU E 5 99  ? 370.227 367.655 464.094 1.00 54.00  ? 99  LEU C CA  1 
ATOM 6031 C C   . LEU E 5 99  ? 371.002 367.843 462.807 1.00 54.00  ? 99  LEU C C   1 
ATOM 6032 O O   . LEU E 5 99  ? 371.560 366.878 462.285 1.00 54.00  ? 99  LEU C O   1 
ATOM 6033 C CB  . LEU E 5 99  ? 368.843 367.098 463.809 1.00 54.00  ? 99  LEU C CB  1 
ATOM 6034 C CG  . LEU E 5 99  ? 368.608 365.680 463.349 1.00 54.00  ? 99  LEU C CG  1 
ATOM 6035 C CD1 . LEU E 5 99  ? 369.251 364.758 464.312 1.00 54.00  ? 99  LEU C CD1 1 
ATOM 6036 C CD2 . LEU E 5 99  ? 367.137 365.468 463.371 1.00 54.00  ? 99  LEU C CD2 1 
ATOM 6037 N N   . LEU E 5 100 ? 371.033 369.060 462.282 1.00 56.42  ? 100 LEU C N   1 
ATOM 6038 C CA  . LEU E 5 100 ? 371.959 369.395 461.212 1.00 56.42  ? 100 LEU C CA  1 
ATOM 6039 C C   . LEU E 5 100 ? 373.369 369.548 461.744 1.00 56.42  ? 100 LEU C C   1 
ATOM 6040 O O   . LEU E 5 100 ? 374.311 368.962 461.211 1.00 56.42  ? 100 LEU C O   1 
ATOM 6041 C CB  . LEU E 5 100 ? 371.513 370.682 460.540 1.00 56.42  ? 100 LEU C CB  1 
ATOM 6042 C CG  . LEU E 5 100 ? 372.474 371.317 459.557 1.00 56.42  ? 100 LEU C CG  1 
ATOM 6043 C CD1 . LEU E 5 100 ? 372.737 370.441 458.367 1.00 56.42  ? 100 LEU C CD1 1 
ATOM 6044 C CD2 . LEU E 5 100 ? 371.876 372.610 459.140 1.00 56.42  ? 100 LEU C CD2 1 
ATOM 6045 N N   . GLY E 5 101 ? 373.529 370.310 462.818 1.00 55.36  ? 101 GLY C N   1 
ATOM 6046 C CA  . GLY E 5 101 ? 374.838 370.604 463.356 1.00 55.36  ? 101 GLY C CA  1 
ATOM 6047 C C   . GLY E 5 101 ? 375.514 369.455 464.064 1.00 55.36  ? 101 GLY C C   1 
ATOM 6048 O O   . GLY E 5 101 ? 376.649 369.622 464.508 1.00 55.36  ? 101 GLY C O   1 
ATOM 6049 N N   . GLU E 5 102 ? 374.850 368.316 464.215 1.00 59.57  ? 102 GLU C N   1 
ATOM 6050 C CA  . GLU E 5 102 ? 375.505 367.132 464.744 1.00 59.57  ? 102 GLU C CA  1 
ATOM 6051 C C   . GLU E 5 102 ? 376.216 366.335 463.671 1.00 59.57  ? 102 GLU C C   1 
ATOM 6052 O O   . GLU E 5 102 ? 377.099 365.538 463.993 1.00 59.57  ? 102 GLU C O   1 
ATOM 6053 C CB  . GLU E 5 102 ? 374.495 366.222 465.441 1.00 59.57  ? 102 GLU C CB  1 
ATOM 6054 C CG  . GLU E 5 102 ? 374.048 366.705 466.795 1.00 59.57  ? 102 GLU C CG  1 
ATOM 6055 C CD  . GLU E 5 102 ? 374.950 366.246 467.918 1.00 59.57  ? 102 GLU C CD  1 
ATOM 6056 O OE1 . GLU E 5 102 ? 375.970 365.587 467.638 1.00 59.57  ? 102 GLU C OE1 1 
ATOM 6057 O OE2 . GLU E 5 102 ? 374.637 366.539 469.090 1.00 59.57  ? 102 GLU C OE2 1 
ATOM 6058 N N   . ILE E 5 103 ? 375.837 366.516 462.412 1.00 55.89  ? 103 ILE C N   1 
ATOM 6059 C CA  . ILE E 5 103 ? 376.516 365.839 461.320 1.00 55.89  ? 103 ILE C CA  1 
ATOM 6060 C C   . ILE E 5 103 ? 377.718 366.643 460.865 1.00 55.89  ? 103 ILE C C   1 
ATOM 6061 O O   . ILE E 5 103 ? 378.779 366.092 460.567 1.00 55.89  ? 103 ILE C O   1 
ATOM 6062 C CB  . ILE E 5 103 ? 375.519 365.592 460.182 1.00 55.89  ? 103 ILE C CB  1 
ATOM 6063 C CG1 . ILE E 5 103 ? 374.428 364.657 460.668 1.00 55.89  ? 103 ILE C CG1 1 
ATOM 6064 C CG2 . ILE E 5 103 ? 376.192 365.008 458.973 1.00 55.89  ? 103 ILE C CG2 1 
ATOM 6065 C CD1 . ILE E 5 103 ? 373.358 364.470 459.675 1.00 55.89  ? 103 ILE C CD1 1 
ATOM 6066 N N   . LEU E 5 104 ? 377.599 367.956 460.866 1.00 54.57  ? 104 LEU C N   1 
ATOM 6067 C CA  . LEU E 5 104 ? 378.684 368.818 460.444 1.00 54.57  ? 104 LEU C CA  1 
ATOM 6068 C C   . LEU E 5 104 ? 379.804 368.920 461.467 1.00 54.57  ? 104 LEU C C   1 
ATOM 6069 O O   . LEU E 5 104 ? 380.793 369.603 461.203 1.00 54.57  ? 104 LEU C O   1 
ATOM 6070 C CB  . LEU E 5 104 ? 378.141 370.207 460.137 1.00 54.57  ? 104 LEU C CB  1 
ATOM 6071 C CG  . LEU E 5 104 ? 376.935 370.255 459.211 1.00 54.57  ? 104 LEU C CG  1 
ATOM 6072 C CD1 . LEU E 5 104 ? 376.498 371.672 459.065 1.00 54.57  ? 104 LEU C CD1 1 
ATOM 6073 C CD2 . LEU E 5 104 ? 377.268 369.681 457.872 1.00 54.57  ? 104 LEU C CD2 1 
ATOM 6074 N N   . ASN E 5 105 ? 379.678 368.293 462.626 1.00 58.43  ? 105 ASN C N   1 
ATOM 6075 C CA  . ASN E 5 105 ? 380.790 368.181 463.548 1.00 58.43  ? 105 ASN C CA  1 
ATOM 6076 C C   . ASN E 5 105 ? 381.587 366.914 463.330 1.00 58.43  ? 105 ASN C C   1 
ATOM 6077 O O   . ASN E 5 105 ? 382.620 366.725 463.972 1.00 58.43  ? 105 ASN C O   1 
ATOM 6078 C CB  . ASN E 5 105 ? 380.300 368.240 464.985 1.00 58.43  ? 105 ASN C CB  1 
ATOM 6079 C CG  . ASN E 5 105 ? 380.044 369.643 465.438 1.00 58.43  ? 105 ASN C CG  1 
ATOM 6080 O OD1 . ASN E 5 105 ? 379.006 369.945 466.002 1.00 58.43  ? 105 ASN C OD1 1 
ATOM 6081 N ND2 . ASN E 5 105 ? 380.991 370.523 465.176 1.00 58.43  ? 105 ASN C ND2 1 
ATOM 6082 N N   . TYR E 5 106 ? 381.136 366.046 462.442 1.00 57.06  ? 106 TYR C N   1 
ATOM 6083 C CA  . TYR E 5 106 ? 381.910 364.877 462.078 1.00 57.06  ? 106 TYR C CA  1 
ATOM 6084 C C   . TYR E 5 106 ? 382.827 365.128 460.900 1.00 57.06  ? 106 TYR C C   1 
ATOM 6085 O O   . TYR E 5 106 ? 383.563 364.223 460.514 1.00 57.06  ? 106 TYR C O   1 
ATOM 6086 C CB  . TYR E 5 106 ? 380.985 363.708 461.754 1.00 57.06  ? 106 TYR C CB  1 
ATOM 6087 C CG  . TYR E 5 106 ? 380.539 362.950 462.973 1.00 57.06  ? 106 TYR C CG  1 
ATOM 6088 C CD1 . TYR E 5 106 ? 381.461 362.339 463.798 1.00 57.06  ? 106 TYR C CD1 1 
ATOM 6089 C CD2 . TYR E 5 106 ? 379.202 362.844 463.298 1.00 57.06  ? 106 TYR C CD2 1 
ATOM 6090 C CE1 . TYR E 5 106 ? 381.068 361.647 464.909 1.00 57.06  ? 106 TYR C CE1 1 
ATOM 6091 C CE2 . TYR E 5 106 ? 378.799 362.153 464.411 1.00 57.06  ? 106 TYR C CE2 1 
ATOM 6092 C CZ  . TYR E 5 106 ? 379.739 361.558 465.209 1.00 57.06  ? 106 TYR C CZ  1 
ATOM 6093 O OH  . TYR E 5 106 ? 379.356 360.861 466.321 1.00 57.06  ? 106 TYR C OH  1 
ATOM 6094 N N   . TYR E 5 107 ? 382.801 366.323 460.324 1.00 57.22  ? 107 TYR C N   1 
ATOM 6095 C CA  . TYR E 5 107 ? 383.630 366.678 459.188 1.00 57.22  ? 107 TYR C CA  1 
ATOM 6096 C C   . TYR E 5 107 ? 384.395 367.956 459.489 1.00 57.22  ? 107 TYR C C   1 
ATOM 6097 O O   . TYR E 5 107 ? 384.113 368.651 460.463 1.00 57.22  ? 107 TYR C O   1 
ATOM 6098 C CB  . TYR E 5 107 ? 382.777 366.843 457.942 1.00 57.22  ? 107 TYR C CB  1 
ATOM 6099 C CG  . TYR E 5 107 ? 382.131 365.555 457.534 1.00 57.22  ? 107 TYR C CG  1 
ATOM 6100 C CD1 . TYR E 5 107 ? 382.829 364.617 456.804 1.00 57.22  ? 107 TYR C CD1 1 
ATOM 6101 C CD2 . TYR E 5 107 ? 380.832 365.268 457.885 1.00 57.22  ? 107 TYR C CD2 1 
ATOM 6102 C CE1 . TYR E 5 107 ? 382.259 363.437 456.437 1.00 57.22  ? 107 TYR C CE1 1 
ATOM 6103 C CE2 . TYR E 5 107 ? 380.250 364.085 457.516 1.00 57.22  ? 107 TYR C CE2 1 
ATOM 6104 C CZ  . TYR E 5 107 ? 380.972 363.180 456.792 1.00 57.22  ? 107 TYR C CZ  1 
ATOM 6105 O OH  . TYR E 5 107 ? 380.408 361.996 456.423 1.00 57.22  ? 107 TYR C OH  1 
ATOM 6106 N N   . THR E 5 108 ? 385.389 368.263 458.656 1.00 58.90  ? 108 THR C N   1 
ATOM 6107 C CA  . THR E 5 108 ? 386.181 369.465 458.860 1.00 58.90  ? 108 THR C CA  1 
ATOM 6108 C C   . THR E 5 108 ? 385.859 370.590 457.898 1.00 58.90  ? 108 THR C C   1 
ATOM 6109 O O   . THR E 5 108 ? 386.026 371.752 458.269 1.00 58.90  ? 108 THR C O   1 
ATOM 6110 C CB  . THR E 5 108 ? 387.675 369.167 458.742 1.00 58.90  ? 108 THR C CB  1 
ATOM 6111 O OG1 . THR E 5 108 ? 387.972 368.820 457.392 1.00 58.90  ? 108 THR C OG1 1 
ATOM 6112 C CG2 . THR E 5 108 ? 388.067 368.040 459.639 1.00 58.90  ? 108 THR C CG2 1 
ATOM 6113 N N   . HIS E 5 109 ? 385.422 370.292 456.682 1.00 60.58  ? 109 HIS C N   1 
ATOM 6114 C CA  . HIS E 5 109 ? 385.084 371.325 455.716 1.00 60.58  ? 109 HIS C CA  1 
ATOM 6115 C C   . HIS E 5 109 ? 383.722 371.023 455.121 1.00 60.58  ? 109 HIS C C   1 
ATOM 6116 O O   . HIS E 5 109 ? 383.504 369.931 454.593 1.00 60.58  ? 109 HIS C O   1 
ATOM 6117 C CB  . HIS E 5 109 ? 386.143 371.421 454.625 1.00 60.58  ? 109 HIS C CB  1 
ATOM 6118 C CG  . HIS E 5 109 ? 387.447 371.966 455.110 1.00 60.58  ? 109 HIS C CG  1 
ATOM 6119 N ND1 . HIS E 5 109 ? 388.612 371.231 455.100 1.00 60.58  ? 109 HIS C ND1 1 
ATOM 6120 C CD2 . HIS E 5 109 ? 387.770 373.175 455.626 1.00 60.58  ? 109 HIS C CD2 1 
ATOM 6121 C CE1 . HIS E 5 109 ? 389.595 371.962 455.593 1.00 60.58  ? 109 HIS C CE1 1 
ATOM 6122 N NE2 . HIS E 5 109 ? 389.111 373.147 455.918 1.00 60.58  ? 109 HIS C NE2 1 
ATOM 6123 N N   . TRP E 5 110 ? 382.815 371.990 455.211 1.00 56.75  ? 110 TRP C N   1 
ATOM 6124 C CA  . TRP E 5 110 ? 381.465 371.874 454.689 1.00 56.75  ? 110 TRP C CA  1 
ATOM 6125 C C   . TRP E 5 110 ? 380.996 373.262 454.295 1.00 56.75  ? 110 TRP C C   1 
ATOM 6126 O O   . TRP E 5 110 ? 381.435 374.259 454.867 1.00 56.75  ? 110 TRP C O   1 
ATOM 6127 C CB  . TRP E 5 110 ? 380.525 371.261 455.718 1.00 56.75  ? 110 TRP C CB  1 
ATOM 6128 C CG  . TRP E 5 110 ? 380.775 371.713 457.103 1.00 56.75  ? 110 TRP C CG  1 
ATOM 6129 C CD1 . TRP E 5 110 ? 381.563 371.115 458.022 1.00 56.75  ? 110 TRP C CD1 1 
ATOM 6130 C CD2 . TRP E 5 110 ? 380.216 372.860 457.739 1.00 56.75  ? 110 TRP C CD2 1 
ATOM 6131 N NE1 . TRP E 5 110 ? 381.544 371.818 459.194 1.00 56.75  ? 110 TRP C NE1 1 
ATOM 6132 C CE2 . TRP E 5 110 ? 380.720 372.898 459.043 1.00 56.75  ? 110 TRP C CE2 1 
ATOM 6133 C CE3 . TRP E 5 110 ? 379.339 373.861 457.329 1.00 56.75  ? 110 TRP C CE3 1 
ATOM 6134 C CZ2 . TRP E 5 110 ? 380.381 373.893 459.937 1.00 56.75  ? 110 TRP C CZ2 1 
ATOM 6135 C CZ3 . TRP E 5 110 ? 379.007 374.840 458.212 1.00 56.75  ? 110 TRP C CZ3 1 
ATOM 6136 C CH2 . TRP E 5 110 ? 379.526 374.855 459.501 1.00 56.75  ? 110 TRP C CH2 1 
ATOM 6137 N N   . SER E 5 111 ? 380.097 373.326 453.317 1.00 61.55  ? 111 SER C N   1 
ATOM 6138 C CA  . SER E 5 111 ? 379.720 374.620 452.769 1.00 61.55  ? 111 SER C CA  1 
ATOM 6139 C C   . SER E 5 111 ? 378.410 374.529 452.008 1.00 61.55  ? 111 SER C C   1 
ATOM 6140 O O   . SER E 5 111 ? 378.365 373.901 450.955 1.00 61.55  ? 111 SER C O   1 
ATOM 6141 C CB  . SER E 5 111 ? 380.798 375.131 451.815 1.00 61.55  ? 111 SER C CB  1 
ATOM 6142 O OG  . SER E 5 111 ? 380.537 374.691 450.497 1.00 61.55  ? 111 SER C OG  1 
ATOM 6143 N N   . GLY E 5 112 ? 377.386 375.232 452.481 1.00 62.67  ? 112 GLY C N   1 
ATOM 6144 C CA  . GLY E 5 112 ? 376.149 375.311 451.726 1.00 62.67  ? 112 GLY C CA  1 
ATOM 6145 C C   . GLY E 5 112 ? 375.177 376.311 452.313 1.00 62.67  ? 112 GLY C C   1 
ATOM 6146 O O   . GLY E 5 112 ? 375.576 377.270 452.969 1.00 62.67  ? 112 GLY C O   1 
ATOM 6147 N N   . SER E 5 113 ? 373.895 376.077 452.049 1.00 66.61  ? 113 SER C N   1 
ATOM 6148 C CA  . SER E 5 113 ? 372.837 377.000 452.422 1.00 66.61  ? 113 SER C CA  1 
ATOM 6149 C C   . SER E 5 113 ? 371.850 376.338 453.372 1.00 66.61  ? 113 SER C C   1 
ATOM 6150 O O   . SER E 5 113 ? 371.761 375.115 453.460 1.00 66.61  ? 113 SER C O   1 
ATOM 6151 C CB  . SER E 5 113 ? 372.117 377.528 451.183 1.00 66.61  ? 113 SER C CB  1 
ATOM 6152 O OG  . SER E 5 113 ? 371.772 376.472 450.314 1.00 66.61  ? 113 SER C OG  1 
ATOM 6153 N N   . ILE E 5 114 ? 371.096 377.177 454.080 1.00 63.30  ? 114 ILE C N   1 
ATOM 6154 C CA  . ILE E 5 114 ? 370.332 376.797 455.265 1.00 63.30  ? 114 ILE C CA  1 
ATOM 6155 C C   . ILE E 5 114 ? 368.916 377.331 455.144 1.00 63.30  ? 114 ILE C C   1 
ATOM 6156 O O   . ILE E 5 114 ? 368.730 378.523 454.899 1.00 63.30  ? 114 ILE C O   1 
ATOM 6157 C CB  . ILE E 5 114 ? 370.982 377.370 456.538 1.00 63.30  ? 114 ILE C CB  1 
ATOM 6158 C CG1 . ILE E 5 114 ? 372.359 376.797 456.738 1.00 63.30  ? 114 ILE C CG1 1 
ATOM 6159 C CG2 . ILE E 5 114 ? 370.176 377.106 457.736 1.00 63.30  ? 114 ILE C CG2 1 
ATOM 6160 C CD1 . ILE E 5 114 ? 372.393 375.337 456.758 1.00 63.30  ? 114 ILE C CD1 1 
ATOM 6161 N N   . LYS E 5 115 ? 367.918 376.472 455.335 1.00 63.44  ? 115 LYS C N   1 
ATOM 6162 C CA  . LYS E 5 115 ? 366.560 376.954 455.539 1.00 63.44  ? 115 LYS C CA  1 
ATOM 6163 C C   . LYS E 5 115 ? 366.328 377.253 457.006 1.00 63.44  ? 115 LYS C C   1 
ATOM 6164 O O   . LYS E 5 115 ? 366.723 376.480 457.877 1.00 63.44  ? 115 LYS C O   1 
ATOM 6165 C CB  . LYS E 5 115 ? 365.527 375.937 455.076 1.00 63.44  ? 115 LYS C CB  1 
ATOM 6166 C CG  . LYS E 5 115 ? 365.354 375.845 453.591 1.00 63.44  ? 115 LYS C CG  1 
ATOM 6167 C CD  . LYS E 5 115 ? 364.394 374.735 453.245 1.00 63.44  ? 115 LYS C CD  1 
ATOM 6168 C CE  . LYS E 5 115 ? 362.994 375.084 453.684 1.00 63.44  ? 115 LYS C CE  1 
ATOM 6169 N NZ  . LYS E 5 115 ? 362.031 374.027 453.298 1.00 63.44  ? 115 LYS C NZ  1 
ATOM 6170 N N   . LEU E 5 116 ? 365.674 378.371 457.278 1.00 58.87  ? 116 LEU C N   1 
ATOM 6171 C CA  . LEU E 5 116 ? 365.306 378.766 458.632 1.00 58.87  ? 116 LEU C CA  1 
ATOM 6172 C C   . LEU E 5 116 ? 363.820 379.091 458.607 1.00 58.87  ? 116 LEU C C   1 
ATOM 6173 O O   . LEU E 5 116 ? 363.409 380.072 457.988 1.00 58.87  ? 116 LEU C O   1 
ATOM 6174 C CB  . LEU E 5 116 ? 366.127 379.957 459.095 1.00 58.87  ? 116 LEU C CB  1 
ATOM 6175 C CG  . LEU E 5 116 ? 367.484 379.681 459.725 1.00 58.87  ? 116 LEU C CG  1 
ATOM 6176 C CD1 . LEU E 5 116 ? 368.313 380.921 459.686 1.00 58.87  ? 116 LEU C CD1 1 
ATOM 6177 C CD2 . LEU E 5 116 ? 367.317 379.241 461.144 1.00 58.87  ? 116 LEU C CD2 1 
ATOM 6178 N N   . THR E 5 117 ? 363.012 378.268 459.257 1.00 58.98  ? 117 THR C N   1 
ATOM 6179 C CA  . THR E 5 117 ? 361.572 378.464 459.302 1.00 58.98  ? 117 THR C CA  1 
ATOM 6180 C C   . THR E 5 117 ? 361.175 378.930 460.691 1.00 58.98  ? 117 THR C C   1 
ATOM 6181 O O   . THR E 5 117 ? 361.633 378.369 461.687 1.00 58.98  ? 117 THR C O   1 
ATOM 6182 C CB  . THR E 5 117 ? 360.829 377.175 458.964 1.00 58.98  ? 117 THR C CB  1 
ATOM 6183 O OG1 . THR E 5 117 ? 361.469 376.523 457.864 1.00 58.98  ? 117 THR C OG1 1 
ATOM 6184 C CG2 . THR E 5 117 ? 359.409 377.472 458.587 1.00 58.98  ? 117 THR C CG2 1 
ATOM 6185 N N   . PHE E 5 118 ? 360.330 379.948 460.756 1.00 57.40  ? 118 PHE C N   1 
ATOM 6186 C CA  . PHE E 5 118 ? 359.799 380.446 462.012 1.00 57.40  ? 118 PHE C CA  1 
ATOM 6187 C C   . PHE E 5 118 ? 358.300 380.205 462.054 1.00 57.40  ? 118 PHE C C   1 
ATOM 6188 O O   . PHE E 5 118 ? 357.619 380.275 461.036 1.00 57.40  ? 118 PHE C O   1 
ATOM 6189 C CB  . PHE E 5 118 ? 360.094 381.933 462.179 1.00 57.40  ? 118 PHE C CB  1 
ATOM 6190 C CG  . PHE E 5 118 ? 361.540 382.265 462.105 1.00 57.40  ? 118 PHE C CG  1 
ATOM 6191 C CD1 . PHE E 5 118 ? 362.332 382.183 463.222 1.00 57.40  ? 118 PHE C CD1 1 
ATOM 6192 C CD2 . PHE E 5 118 ? 362.111 382.660 460.917 1.00 57.40  ? 118 PHE C CD2 1 
ATOM 6193 C CE1 . PHE E 5 118 ? 363.665 382.478 463.153 1.00 57.40  ? 118 PHE C CE1 1 
ATOM 6194 C CE2 . PHE E 5 118 ? 363.446 382.957 460.847 1.00 57.40  ? 118 PHE C CE2 1 
ATOM 6195 C CZ  . PHE E 5 118 ? 364.221 382.869 461.965 1.00 57.40  ? 118 PHE C CZ  1 
ATOM 6196 N N   . MET E 5 119 ? 357.786 379.919 463.244 1.00 56.79  ? 119 MET C N   1 
ATOM 6197 C CA  . MET E 5 119 ? 356.369 379.629 463.390 1.00 56.79  ? 119 MET C CA  1 
ATOM 6198 C C   . MET E 5 119 ? 355.832 380.387 464.587 1.00 56.79  ? 119 MET C C   1 
ATOM 6199 O O   . MET E 5 119 ? 356.388 380.286 465.680 1.00 56.79  ? 119 MET C O   1 
ATOM 6200 C CB  . MET E 5 119 ? 356.122 378.135 463.563 1.00 56.79  ? 119 MET C CB  1 
ATOM 6201 C CG  . MET E 5 119 ? 354.663 377.779 463.599 1.00 56.79  ? 119 MET C CG  1 
ATOM 6202 S SD  . MET E 5 119 ? 354.339 376.017 463.495 1.00 56.79  ? 119 MET C SD  1 
ATOM 6203 C CE  . MET E 5 119 ? 355.099 375.472 465.003 1.00 56.79  ? 119 MET C CE  1 
ATOM 6204 N N   . PHE E 5 120 ? 354.757 381.136 464.379 1.00 57.54  ? 120 PHE C N   1 
ATOM 6205 C CA  . PHE E 5 120 ? 354.180 381.974 465.421 1.00 57.54  ? 120 PHE C CA  1 
ATOM 6206 C C   . PHE E 5 120 ? 353.120 381.183 466.167 1.00 57.54  ? 120 PHE C C   1 
ATOM 6207 O O   . PHE E 5 120 ? 352.004 381.015 465.673 1.00 57.54  ? 120 PHE C O   1 
ATOM 6208 C CB  . PHE E 5 120 ? 353.579 383.234 464.821 1.00 57.54  ? 120 PHE C CB  1 
ATOM 6209 C CG  . PHE E 5 120 ? 353.016 384.168 465.831 1.00 57.54  ? 120 PHE C CG  1 
ATOM 6210 C CD1 . PHE E 5 120 ? 353.843 384.967 466.581 1.00 57.54  ? 120 PHE C CD1 1 
ATOM 6211 C CD2 . PHE E 5 120 ? 351.658 384.256 466.024 1.00 57.54  ? 120 PHE C CD2 1 
ATOM 6212 C CE1 . PHE E 5 120 ? 353.325 385.829 467.505 1.00 57.54  ? 120 PHE C CE1 1 
ATOM 6213 C CE2 . PHE E 5 120 ? 351.137 385.125 466.941 1.00 57.54  ? 120 PHE C CE2 1 
ATOM 6214 C CZ  . PHE E 5 120 ? 351.970 385.907 467.683 1.00 57.54  ? 120 PHE C CZ  1 
ATOM 6215 N N   . CYS E 5 121 ? 353.459 380.711 467.359 1.00 59.49  ? 121 CYS C N   1 
ATOM 6216 C CA  . CYS E 5 121 ? 352.517 379.960 468.181 1.00 59.49  ? 121 CYS C CA  1 
ATOM 6217 C C   . CYS E 5 121 ? 351.844 380.878 469.194 1.00 59.49  ? 121 CYS C C   1 
ATOM 6218 O O   . CYS E 5 121 ? 351.970 380.728 470.400 1.00 59.49  ? 121 CYS C O   1 
ATOM 6219 C CB  . CYS E 5 121 ? 353.226 378.808 468.870 1.00 59.49  ? 121 CYS C CB  1 
ATOM 6220 S SG  . CYS E 5 121 ? 354.133 377.745 467.762 1.00 59.49  ? 121 CYS C SG  1 
ATOM 6221 N N   . GLY E 5 122 ? 351.118 381.849 468.671 1.00 59.35  ? 122 GLY C N   1 
ATOM 6222 C CA  . GLY E 5 122 ? 350.337 382.723 469.510 1.00 59.35  ? 122 GLY C CA  1 
ATOM 6223 C C   . GLY E 5 122 ? 348.874 382.461 469.271 1.00 59.35  ? 122 GLY C C   1 
ATOM 6224 O O   . GLY E 5 122 ? 348.518 381.380 468.803 1.00 59.35  ? 122 GLY C O   1 
ATOM 6225 N N   . SER E 5 123 ? 348.017 383.426 469.578 1.00 58.39  ? 123 SER C N   1 
ATOM 6226 C CA  . SER E 5 123 ? 346.593 383.209 469.416 1.00 58.39  ? 123 SER C CA  1 
ATOM 6227 C C   . SER E 5 123 ? 346.199 383.371 467.960 1.00 58.39  ? 123 SER C C   1 
ATOM 6228 O O   . SER E 5 123 ? 346.968 383.855 467.133 1.00 58.39  ? 123 SER C O   1 
ATOM 6229 C CB  . SER E 5 123 ? 345.805 384.177 470.281 1.00 58.39  ? 123 SER C CB  1 
ATOM 6230 O OG  . SER E 5 123 ? 344.425 383.918 470.166 1.00 58.39  ? 123 SER C OG  1 
ATOM 6231 N N   . ALA E 5 124 ? 344.982 382.952 467.641 1.00 59.80  ? 124 ALA C N   1 
ATOM 6232 C CA  . ALA E 5 124 ? 344.464 383.138 466.297 1.00 59.80  ? 124 ALA C CA  1 
ATOM 6233 C C   . ALA E 5 124 ? 343.911 384.530 466.080 1.00 59.80  ? 124 ALA C C   1 
ATOM 6234 O O   . ALA E 5 124 ? 343.677 384.916 464.934 1.00 59.80  ? 124 ALA C O   1 
ATOM 6235 C CB  . ALA E 5 124 ? 343.374 382.113 465.991 1.00 59.80  ? 124 ALA C CB  1 
ATOM 6236 N N   . MET E 5 125 ? 343.711 385.286 467.151 1.00 62.80  ? 125 MET C N   1 
ATOM 6237 C CA  . MET E 5 125 ? 343.151 386.621 467.096 1.00 62.80  ? 125 MET C CA  1 
ATOM 6238 C C   . MET E 5 125 ? 344.204 387.711 467.204 1.00 62.80  ? 125 MET C C   1 
ATOM 6239 O O   . MET E 5 125 ? 343.859 388.889 467.097 1.00 62.80  ? 125 MET C O   1 
ATOM 6240 C CB  . MET E 5 125 ? 342.128 386.796 468.218 1.00 62.80  ? 125 MET C CB  1 
ATOM 6241 C CG  . MET E 5 125 ? 341.002 385.786 468.210 1.00 62.80  ? 125 MET C CG  1 
ATOM 6242 S SD  . MET E 5 125 ? 339.620 386.347 467.218 1.00 62.80  ? 125 MET C SD  1 
ATOM 6243 C CE  . MET E 5 125 ? 338.328 385.257 467.783 1.00 62.80  ? 125 MET C CE  1 
ATOM 6244 N N   . ALA E 5 126 ? 345.466 387.356 467.413 1.00 61.78  ? 126 ALA C N   1 
ATOM 6245 C CA  . ALA E 5 126 ? 346.535 388.334 467.531 1.00 61.78  ? 126 ALA C CA  1 
ATOM 6246 C C   . ALA E 5 126 ? 347.131 388.636 466.168 1.00 61.78  ? 126 ALA C C   1 
ATOM 6247 O O   . ALA E 5 126 ? 347.248 387.752 465.321 1.00 61.78  ? 126 ALA C O   1 
ATOM 6248 C CB  . ALA E 5 126 ? 347.628 387.836 468.468 1.00 61.78  ? 126 ALA C CB  1 
ATOM 6249 N N   . THR E 5 127 ? 347.502 389.893 465.964 1.00 63.96  ? 127 THR C N   1 
ATOM 6250 C CA  . THR E 5 127 ? 348.055 390.389 464.714 1.00 63.96  ? 127 THR C CA  1 
ATOM 6251 C C   . THR E 5 127 ? 349.326 391.172 465.000 1.00 63.96  ? 127 THR C C   1 
ATOM 6252 O O   . THR E 5 127 ? 349.602 391.546 466.136 1.00 63.96  ? 127 THR C O   1 
ATOM 6253 C CB  . THR E 5 127 ? 347.046 391.273 463.984 1.00 63.96  ? 127 THR C CB  1 
ATOM 6254 O OG1 . THR E 5 127 ? 346.442 392.163 464.922 1.00 63.96  ? 127 THR C OG1 1 
ATOM 6255 C CG2 . THR E 5 127 ? 345.969 390.438 463.337 1.00 63.96  ? 127 THR C CG2 1 
ATOM 6256 N N   . GLY E 5 128 ? 350.091 391.439 463.956 1.00 60.19  ? 128 GLY C N   1 
ATOM 6257 C CA  . GLY E 5 128 ? 351.318 392.192 464.103 1.00 60.19  ? 128 GLY C CA  1 
ATOM 6258 C C   . GLY E 5 128 ? 352.177 392.054 462.868 1.00 60.19  ? 128 GLY C C   1 
ATOM 6259 O O   . GLY E 5 128 ? 351.765 391.494 461.858 1.00 60.19  ? 128 GLY C O   1 
ATOM 6260 N N   . LYS E 5 129 ? 353.390 392.583 462.975 1.00 56.91  ? 129 LYS C N   1 
ATOM 6261 C CA  . LYS E 5 129 ? 354.352 392.503 461.891 1.00 56.91  ? 129 LYS C CA  1 
ATOM 6262 C C   . LYS E 5 129 ? 355.745 392.364 462.476 1.00 56.91  ? 129 LYS C C   1 
ATOM 6263 O O   . LYS E 5 129 ? 356.029 392.881 463.556 1.00 56.91  ? 129 LYS C O   1 
ATOM 6264 C CB  . LYS E 5 129 ? 354.293 393.731 460.985 1.00 56.91  ? 129 LYS C CB  1 
ATOM 6265 C CG  . LYS E 5 129 ? 353.306 393.617 459.862 1.00 56.91  ? 129 LYS C CG  1 
ATOM 6266 C CD  . LYS E 5 129 ? 353.449 394.753 458.906 1.00 56.91  ? 129 LYS C CD  1 
ATOM 6267 C CE  . LYS E 5 129 ? 352.147 395.024 458.206 1.00 56.91  ? 129 LYS C CE  1 
ATOM 6268 N NZ  . LYS E 5 129 ? 351.698 393.843 457.454 1.00 56.91  ? 129 LYS C NZ  1 
ATOM 6269 N N   . PHE E 5 130 ? 356.613 391.668 461.749 1.00 56.97  ? 130 PHE C N   1 
ATOM 6270 C CA  . PHE E 5 130 ? 357.996 391.483 462.154 1.00 56.97  ? 130 PHE C CA  1 
ATOM 6271 C C   . PHE E 5 130 ? 358.903 391.727 460.962 1.00 56.97  ? 130 PHE C C   1 
ATOM 6272 O O   . PHE E 5 130 ? 358.506 391.500 459.820 1.00 56.97  ? 130 PHE C O   1 
ATOM 6273 C CB  . PHE E 5 130 ? 358.244 390.073 462.687 1.00 56.97  ? 130 PHE C CB  1 
ATOM 6274 C CG  . PHE E 5 130 ? 357.581 389.790 463.991 1.00 56.97  ? 130 PHE C CG  1 
ATOM 6275 C CD1 . PHE E 5 130 ? 358.064 390.339 465.154 1.00 56.97  ? 130 PHE C CD1 1 
ATOM 6276 C CD2 . PHE E 5 130 ? 356.480 388.961 464.055 1.00 56.97  ? 130 PHE C CD2 1 
ATOM 6277 C CE1 . PHE E 5 130 ? 357.453 390.080 466.352 1.00 56.97  ? 130 PHE C CE1 1 
ATOM 6278 C CE2 . PHE E 5 130 ? 355.871 388.700 465.253 1.00 56.97  ? 130 PHE C CE2 1 
ATOM 6279 C CZ  . PHE E 5 130 ? 356.358 389.261 466.400 1.00 56.97  ? 130 PHE C CZ  1 
ATOM 6280 N N   . LEU E 5 131 ? 360.117 392.187 461.231 1.00 56.64  ? 131 LEU C N   1 
ATOM 6281 C CA  . LEU E 5 131 ? 361.172 392.211 460.232 1.00 56.64  ? 131 LEU C CA  1 
ATOM 6282 C C   . LEU E 5 131 ? 362.127 391.058 460.473 1.00 56.64  ? 131 LEU C C   1 
ATOM 6283 O O   . LEU E 5 131 ? 362.415 390.705 461.613 1.00 56.64  ? 131 LEU C O   1 
ATOM 6284 C CB  . LEU E 5 131 ? 361.950 393.518 460.287 1.00 56.64  ? 131 LEU C CB  1 
ATOM 6285 C CG  . LEU E 5 131 ? 361.518 394.648 459.378 1.00 56.64  ? 131 LEU C CG  1 
ATOM 6286 C CD1 . LEU E 5 131 ? 362.307 395.849 459.737 1.00 56.64  ? 131 LEU C CD1 1 
ATOM 6287 C CD2 . LEU E 5 131 ? 361.810 394.267 457.978 1.00 56.64  ? 131 LEU C CD2 1 
ATOM 6288 N N   . LEU E 5 132 ? 362.636 390.483 459.395 1.00 57.13  ? 132 LEU C N   1 
ATOM 6289 C CA  . LEU E 5 132 ? 363.557 389.350 459.487 1.00 57.13  ? 132 LEU C CA  1 
ATOM 6290 C C   . LEU E 5 132 ? 364.830 389.710 458.738 1.00 57.13  ? 132 LEU C C   1 
ATOM 6291 O O   . LEU E 5 132 ? 364.965 389.437 457.548 1.00 57.13  ? 132 LEU C O   1 
ATOM 6292 C CB  . LEU E 5 132 ? 362.925 388.100 458.946 1.00 57.13  ? 132 LEU C CB  1 
ATOM 6293 C CG  . LEU E 5 132 ? 362.070 387.350 459.951 1.00 57.13  ? 132 LEU C CG  1 
ATOM 6294 C CD1 . LEU E 5 132 ? 361.367 386.232 459.258 1.00 57.13  ? 132 LEU C CD1 1 
ATOM 6295 C CD2 . LEU E 5 132 ? 362.941 386.819 461.051 1.00 57.13  ? 132 LEU C CD2 1 
ATOM 6296 N N   . ALA E 5 133 ? 365.777 390.303 459.446 1.00 58.72  ? 133 ALA C N   1 
ATOM 6297 C CA  . ALA E 5 133 ? 366.975 390.835 458.823 1.00 58.72  ? 133 ALA C CA  1 
ATOM 6298 C C   . ALA E 5 133 ? 368.063 389.776 458.756 1.00 58.72  ? 133 ALA C C   1 
ATOM 6299 O O   . ALA E 5 133 ? 368.202 388.961 459.669 1.00 58.72  ? 133 ALA C O   1 
ATOM 6300 C CB  . ALA E 5 133 ? 367.477 392.051 459.594 1.00 58.72  ? 133 ALA C CB  1 
ATOM 6301 N N   . TYR E 5 134 ? 368.831 389.797 457.676 1.00 60.01  ? 134 TYR C N   1 
ATOM 6302 C CA  . TYR E 5 134 ? 370.008 388.957 457.518 1.00 60.01  ? 134 TYR C CA  1 
ATOM 6303 C C   . TYR E 5 134 ? 371.191 389.849 457.178 1.00 60.01  ? 134 TYR C C   1 
ATOM 6304 O O   . TYR E 5 134 ? 371.166 390.549 456.165 1.00 60.01  ? 134 TYR C O   1 
ATOM 6305 C CB  . TYR E 5 134 ? 369.787 387.919 456.424 1.00 60.01  ? 134 TYR C CB  1 
ATOM 6306 C CG  . TYR E 5 134 ? 371.053 387.297 455.903 1.00 60.01  ? 134 TYR C CG  1 
ATOM 6307 C CD1 . TYR E 5 134 ? 371.874 386.557 456.731 1.00 60.01  ? 134 TYR C CD1 1 
ATOM 6308 C CD2 . TYR E 5 134 ? 371.419 387.440 454.579 1.00 60.01  ? 134 TYR C CD2 1 
ATOM 6309 C CE1 . TYR E 5 134 ? 373.031 385.989 456.259 1.00 60.01  ? 134 TYR C CE1 1 
ATOM 6310 C CE2 . TYR E 5 134 ? 372.572 386.871 454.099 1.00 60.01  ? 134 TYR C CE2 1 
ATOM 6311 C CZ  . TYR E 5 134 ? 373.372 386.148 454.946 1.00 60.01  ? 134 TYR C CZ  1 
ATOM 6312 O OH  . TYR E 5 134 ? 374.522 385.574 454.478 1.00 60.01  ? 134 TYR C OH  1 
ATOM 6313 N N   . SER E 5 135 ? 372.214 389.826 458.017 1.00 60.46  ? 135 SER C N   1 
ATOM 6314 C CA  . SER E 5 135 ? 373.361 390.615 457.601 1.00 60.46  ? 135 SER C CA  1 
ATOM 6315 C C   . SER E 5 135 ? 374.390 389.730 456.926 1.00 60.46  ? 135 SER C C   1 
ATOM 6316 O O   . SER E 5 135 ? 374.709 388.659 457.438 1.00 60.46  ? 135 SER C O   1 
ATOM 6317 C CB  . SER E 5 135 ? 374.009 391.301 458.795 1.00 60.46  ? 135 SER C CB  1 
ATOM 6318 O OG  . SER E 5 135 ? 373.026 391.834 459.650 1.00 60.46  ? 135 SER C OG  1 
ATOM 6319 N N   . PRO E 5 136 ? 374.930 390.134 455.784 1.00 61.87  ? 136 PRO C N   1 
ATOM 6320 C CA  . PRO E 5 136 ? 375.918 389.315 455.100 1.00 61.87  ? 136 PRO C CA  1 
ATOM 6321 C C   . PRO E 5 136 ? 377.246 389.371 455.828 1.00 61.87  ? 136 PRO C C   1 
ATOM 6322 O O   . PRO E 5 136 ? 377.444 390.241 456.687 1.00 61.87  ? 136 PRO C O   1 
ATOM 6323 C CB  . PRO E 5 136 ? 376.010 389.966 453.713 1.00 61.87  ? 136 PRO C CB  1 
ATOM 6324 C CG  . PRO E 5 136 ? 374.846 390.857 453.619 1.00 61.87  ? 136 PRO C CG  1 
ATOM 6325 C CD  . PRO E 5 136 ? 374.595 391.324 455.000 1.00 61.87  ? 136 PRO C CD  1 
ATOM 6326 N N   . PRO E 5 137 ? 378.163 388.443 455.553 1.00 62.95  ? 137 PRO C N   1 
ATOM 6327 C CA  . PRO E 5 137 ? 379.480 388.506 456.193 1.00 62.95  ? 137 PRO C CA  1 
ATOM 6328 C C   . PRO E 5 137 ? 380.262 389.719 455.724 1.00 62.95  ? 137 PRO C C   1 
ATOM 6329 O O   . PRO E 5 137 ? 380.505 389.896 454.530 1.00 62.95  ? 137 PRO C O   1 
ATOM 6330 C CB  . PRO E 5 137 ? 380.149 387.200 455.757 1.00 62.95  ? 137 PRO C CB  1 
ATOM 6331 C CG  . PRO E 5 137 ? 379.358 386.725 454.613 1.00 62.95  ? 137 PRO C CG  1 
ATOM 6332 C CD  . PRO E 5 137 ? 377.973 387.157 454.870 1.00 62.95  ? 137 PRO C CD  1 
ATOM 6333 N N   . GLY E 5 138 ? 380.640 390.560 456.677 1.00 65.77  ? 138 GLY C N   1 
ATOM 6334 C CA  . GLY E 5 138 ? 381.335 391.793 456.380 1.00 65.77  ? 138 GLY C CA  1 
ATOM 6335 C C   . GLY E 5 138 ? 380.550 393.004 456.829 1.00 65.77  ? 138 GLY C C   1 
ATOM 6336 O O   . GLY E 5 138 ? 381.110 393.941 457.402 1.00 65.77  ? 138 GLY C O   1 
ATOM 6337 N N   . ALA E 5 139 ? 379.245 392.987 456.588 1.00 68.46  ? 139 ALA C N   1 
ATOM 6338 C CA  . ALA E 5 139 ? 378.371 394.033 457.084 1.00 68.46  ? 139 ALA C CA  1 
ATOM 6339 C C   . ALA E 5 139 ? 378.114 393.834 458.569 1.00 68.46  ? 139 ALA C C   1 
ATOM 6340 O O   . ALA E 5 139 ? 377.995 392.708 459.051 1.00 68.46  ? 139 ALA C O   1 
ATOM 6341 C CB  . ALA E 5 139 ? 377.051 394.034 456.320 1.00 68.46  ? 139 ALA C CB  1 
ATOM 6342 N N   . GLY E 5 140 ? 378.033 394.932 459.296 1.00 68.70  ? 140 GLY C N   1 
ATOM 6343 C CA  . GLY E 5 140 ? 377.846 394.848 460.727 1.00 68.70  ? 140 GLY C CA  1 
ATOM 6344 C C   . GLY E 5 140 ? 376.432 394.474 461.116 1.00 68.70  ? 140 GLY C C   1 
ATOM 6345 O O   . GLY E 5 140 ? 375.535 394.364 460.286 1.00 68.70  ? 140 GLY C O   1 
ATOM 6346 N N   . VAL E 5 141 ? 376.242 394.256 462.410 1.00 65.92  ? 141 VAL C N   1 
ATOM 6347 C CA  . VAL E 5 141 ? 374.894 394.005 462.927 1.00 65.92  ? 141 VAL C CA  1 
ATOM 6348 C C   . VAL E 5 141 ? 374.106 395.309 462.908 1.00 65.92  ? 141 VAL C C   1 
ATOM 6349 O O   . VAL E 5 141 ? 374.677 396.375 463.196 1.00 65.92  ? 141 VAL C O   1 
ATOM 6350 C CB  . VAL E 5 141 ? 374.970 393.394 464.335 1.00 65.92  ? 141 VAL C CB  1 
ATOM 6351 C CG1 . VAL E 5 141 ? 375.784 394.245 465.292 1.00 65.92  ? 141 VAL C CG1 1 
ATOM 6352 C CG2 . VAL E 5 141 ? 373.600 393.140 464.911 1.00 65.92  ? 141 VAL C CG2 1 
ATOM 6353 N N   . PRO E 5 142 ? 372.848 395.309 462.472 1.00 64.26  ? 142 PRO C N   1 
ATOM 6354 C CA  . PRO E 5 142 ? 372.074 396.551 462.491 1.00 64.26  ? 142 PRO C CA  1 
ATOM 6355 C C   . PRO E 5 142 ? 371.715 396.936 463.913 1.00 64.26  ? 142 PRO C C   1 
ATOM 6356 O O   . PRO E 5 142 ? 371.455 396.077 464.755 1.00 64.26  ? 142 PRO C O   1 
ATOM 6357 C CB  . PRO E 5 142 ? 370.832 396.209 461.667 1.00 64.26  ? 142 PRO C CB  1 
ATOM 6358 C CG  . PRO E 5 142 ? 370.754 394.755 461.688 1.00 64.26  ? 142 PRO C CG  1 
ATOM 6359 C CD  . PRO E 5 142 ? 372.147 394.254 461.732 1.00 64.26  ? 142 PRO C CD  1 
ATOM 6360 N N   . LYS E 5 143 ? 371.732 398.236 464.183 1.00 67.95  ? 143 LYS C N   1 
ATOM 6361 C CA  . LYS E 5 143 ? 371.422 398.758 465.501 1.00 67.95  ? 143 LYS C CA  1 
ATOM 6362 C C   . LYS E 5 143 ? 370.111 399.525 465.544 1.00 67.95  ? 143 LYS C C   1 
ATOM 6363 O O   . LYS E 5 143 ? 369.711 399.985 466.615 1.00 67.95  ? 143 LYS C O   1 
ATOM 6364 C CB  . LYS E 5 143 ? 372.565 399.638 465.985 1.00 67.95  ? 143 LYS C CB  1 
ATOM 6365 C CG  . LYS E 5 143 ? 372.856 400.810 465.092 1.00 67.95  ? 143 LYS C CG  1 
ATOM 6366 C CD  . LYS E 5 143 ? 373.965 401.641 465.693 1.00 67.95  ? 143 LYS C CD  1 
ATOM 6367 C CE  . LYS E 5 143 ? 375.292 400.906 465.626 1.00 67.95  ? 143 LYS C CE  1 
ATOM 6368 N NZ  . LYS E 5 143 ? 376.411 401.747 466.121 1.00 67.95  ? 143 LYS C NZ  1 
ATOM 6369 N N   . ASN E 5 144 ? 369.429 399.664 464.416 1.00 67.73  ? 144 ASN C N   1 
ATOM 6370 C CA  . ASN E 5 144 ? 368.104 400.259 464.402 1.00 67.73  ? 144 ASN C CA  1 
ATOM 6371 C C   . ASN E 5 144 ? 367.211 399.380 463.556 1.00 67.73  ? 144 ASN C C   1 
ATOM 6372 O O   . ASN E 5 144 ? 367.678 398.484 462.855 1.00 67.73  ? 144 ASN C O   1 
ATOM 6373 C CB  . ASN E 5 144 ? 368.099 401.681 463.839 1.00 67.73  ? 144 ASN C CB  1 
ATOM 6374 C CG  . ASN E 5 144 ? 368.704 402.679 464.776 1.00 67.73  ? 144 ASN C CG  1 
ATOM 6375 O OD1 . ASN E 5 144 ? 368.510 402.610 465.987 1.00 67.73  ? 144 ASN C OD1 1 
ATOM 6376 N ND2 . ASN E 5 144 ? 369.426 403.639 464.222 1.00 67.73  ? 144 ASN C ND2 1 
ATOM 6377 N N   . ARG E 5 145 ? 365.916 399.648 463.630 1.00 64.18  ? 145 ARG C N   1 
ATOM 6378 C CA  . ARG E 5 145 ? 365.010 399.010 462.694 1.00 64.18  ? 145 ARG C CA  1 
ATOM 6379 C C   . ARG E 5 145 ? 365.204 399.562 461.295 1.00 64.18  ? 145 ARG C C   1 
ATOM 6380 O O   . ARG E 5 145 ? 364.986 398.845 460.316 1.00 64.18  ? 145 ARG C O   1 
ATOM 6381 C CB  . ARG E 5 145 ? 363.574 399.206 463.157 1.00 64.18  ? 145 ARG C CB  1 
ATOM 6382 C CG  . ARG E 5 145 ? 362.549 398.394 462.422 1.00 64.18  ? 145 ARG C CG  1 
ATOM 6383 C CD  . ARG E 5 145 ? 361.269 399.167 462.323 1.00 64.18  ? 145 ARG C CD  1 
ATOM 6384 N NE  . ARG E 5 145 ? 361.466 400.435 461.644 1.00 64.18  ? 145 ARG C NE  1 
ATOM 6385 C CZ  . ARG E 5 145 ? 361.201 400.630 460.362 1.00 64.18  ? 145 ARG C CZ  1 
ATOM 6386 N NH1 . ARG E 5 145 ? 361.411 401.814 459.810 1.00 64.18  ? 145 ARG C NH1 1 
ATOM 6387 N NH2 . ARG E 5 145 ? 360.723 399.638 459.633 1.00 64.18  ? 145 ARG C NH2 1 
ATOM 6388 N N   . LYS E 5 146 ? 365.641 400.817 461.185 1.00 67.50  ? 146 LYS C N   1 
ATOM 6389 C CA  . LYS E 5 146 ? 365.692 401.476 459.887 1.00 67.50  ? 146 LYS C CA  1 
ATOM 6390 C C   . LYS E 5 146 ? 366.803 400.911 459.022 1.00 67.50  ? 146 LYS C C   1 
ATOM 6391 O O   . LYS E 5 146 ? 366.558 400.495 457.889 1.00 67.50  ? 146 LYS C O   1 
ATOM 6392 C CB  . LYS E 5 146 ? 365.871 402.977 460.062 1.00 67.50  ? 146 LYS C CB  1 
ATOM 6393 C CG  . LYS E 5 146 ? 365.916 403.719 458.752 1.00 67.50  ? 146 LYS C CG  1 
ATOM 6394 C CD  . LYS E 5 146 ? 366.439 405.127 458.921 1.00 67.50  ? 146 LYS C CD  1 
ATOM 6395 C CE  . LYS E 5 146 ? 366.542 405.814 457.576 1.00 67.50  ? 146 LYS C CE  1 
ATOM 6396 N NZ  . LYS E 5 146 ? 367.184 407.150 457.667 1.00 67.50  ? 146 LYS C NZ  1 
ATOM 6397 N N   . ASP E 5 147 ? 368.027 400.865 459.539 1.00 69.73  ? 147 ASP C N   1 
ATOM 6398 C CA  . ASP E 5 147 ? 369.126 400.311 458.761 1.00 69.73  ? 147 ASP C CA  1 
ATOM 6399 C C   . ASP E 5 147 ? 369.082 398.796 458.670 1.00 69.73  ? 147 ASP C C   1 
ATOM 6400 O O   . ASP E 5 147 ? 369.806 398.223 457.855 1.00 69.73  ? 147 ASP C O   1 
ATOM 6401 C CB  . ASP E 5 147 ? 370.472 400.758 459.327 1.00 69.73  ? 147 ASP C CB  1 
ATOM 6402 C CG  . ASP E 5 147 ? 370.615 400.465 460.790 1.00 69.73  ? 147 ASP C CG  1 
ATOM 6403 O OD1 . ASP E 5 147 ? 369.612 400.097 461.417 1.00 69.73  ? 147 ASP C OD1 1 
ATOM 6404 O OD2 . ASP E 5 147 ? 371.734 400.604 461.319 1.00 69.73  ? 147 ASP C OD2 1 
ATOM 6405 N N   . ALA E 5 148 ? 368.264 398.139 459.486 1.00 66.15  ? 148 ALA C N   1 
ATOM 6406 C CA  . ALA E 5 148 ? 367.946 396.744 459.241 1.00 66.15  ? 148 ALA C CA  1 
ATOM 6407 C C   . ALA E 5 148 ? 367.035 396.587 458.038 1.00 66.15  ? 148 ALA C C   1 
ATOM 6408 O O   . ALA E 5 148 ? 367.146 395.602 457.306 1.00 66.15  ? 148 ALA C O   1 
ATOM 6409 C CB  . ALA E 5 148 ? 367.287 396.135 460.470 1.00 66.15  ? 148 ALA C CB  1 
ATOM 6410 N N   . MET E 5 149 ? 366.133 397.543 457.824 1.00 67.15  ? 149 MET C N   1 
ATOM 6411 C CA  . MET E 5 149 ? 365.277 397.526 456.648 1.00 67.15  ? 149 MET C CA  1 
ATOM 6412 C C   . MET E 5 149 ? 366.060 397.822 455.382 1.00 67.15  ? 149 MET C C   1 
ATOM 6413 O O   . MET E 5 149 ? 365.715 397.311 454.315 1.00 67.15  ? 149 MET C O   1 
ATOM 6414 C CB  . MET E 5 149 ? 364.145 398.538 456.812 1.00 67.15  ? 149 MET C CB  1 
ATOM 6415 C CG  . MET E 5 149 ? 363.019 398.404 455.812 1.00 67.15  ? 149 MET C CG  1 
ATOM 6416 S SD  . MET E 5 149 ? 363.170 399.459 454.352 1.00 67.15  ? 149 MET C SD  1 
ATOM 6417 C CE  . MET E 5 149 ? 363.232 401.092 455.074 1.00 67.15  ? 149 MET C CE  1 
ATOM 6418 N N   . LEU E 5 150 ? 367.119 398.623 455.476 1.00 66.71  ? 150 LEU C N   1 
ATOM 6419 C CA  . LEU E 5 150 ? 367.856 399.012 454.283 1.00 66.71  ? 150 LEU C CA  1 
ATOM 6420 C C   . LEU E 5 150 ? 368.698 397.875 453.722 1.00 66.71  ? 150 LEU C C   1 
ATOM 6421 O O   . LEU E 5 150 ? 369.115 397.940 452.564 1.00 66.71  ? 150 LEU C O   1 
ATOM 6422 C CB  . LEU E 5 150 ? 368.732 400.220 454.587 1.00 66.71  ? 150 LEU C CB  1 
ATOM 6423 C CG  . LEU E 5 150 ? 367.972 401.462 455.046 1.00 66.71  ? 150 LEU C CG  1 
ATOM 6424 C CD1 . LEU E 5 150 ? 368.921 402.611 455.325 1.00 66.71  ? 150 LEU C CD1 1 
ATOM 6425 C CD2 . LEU E 5 150 ? 366.950 401.861 454.014 1.00 66.71  ? 150 LEU C CD2 1 
ATOM 6426 N N   . GLY E 5 151 ? 368.956 396.836 454.510 1.00 66.47  ? 151 GLY C N   1 
ATOM 6427 C CA  . GLY E 5 151 ? 369.564 395.629 453.998 1.00 66.47  ? 151 GLY C CA  1 
ATOM 6428 C C   . GLY E 5 151 ? 368.527 394.692 453.420 1.00 66.47  ? 151 GLY C C   1 
ATOM 6429 O O   . GLY E 5 151 ? 367.444 395.093 453.002 1.00 66.47  ? 151 GLY C O   1 
ATOM 6430 N N   . THR E 5 152 ? 368.872 393.410 453.388 1.00 61.96  ? 152 THR C N   1 
ATOM 6431 C CA  . THR E 5 152 ? 367.911 392.403 452.964 1.00 61.96  ? 152 THR C CA  1 
ATOM 6432 C C   . THR E 5 152 ? 367.056 391.946 454.138 1.00 61.96  ? 152 THR C C   1 
ATOM 6433 O O   . THR E 5 152 ? 367.527 391.868 455.273 1.00 61.96  ? 152 THR C O   1 
ATOM 6434 C CB  . THR E 5 152 ? 368.625 391.221 452.316 1.00 61.96  ? 152 THR C CB  1 
ATOM 6435 O OG1 . THR E 5 152 ? 367.680 390.182 452.040 1.00 61.96  ? 152 THR C OG1 1 
ATOM 6436 C CG2 . THR E 5 152 ? 369.735 390.701 453.182 1.00 61.96  ? 152 THR C CG2 1 
ATOM 6437 N N   . HIS E 5 153 ? 365.786 391.656 453.860 1.00 57.82  ? 153 HIS C N   1 
ATOM 6438 C CA  . HIS E 5 153 ? 364.807 391.419 454.911 1.00 57.82  ? 153 HIS C CA  1 
ATOM 6439 C C   . HIS E 5 153 ? 363.563 390.776 454.322 1.00 57.82  ? 153 HIS C C   1 
ATOM 6440 O O   . HIS E 5 153 ? 363.393 390.699 453.106 1.00 57.82  ? 153 HIS C O   1 
ATOM 6441 C CB  . HIS E 5 153 ? 364.426 392.716 455.619 1.00 57.82  ? 153 HIS C CB  1 
ATOM 6442 C CG  . HIS E 5 153 ? 363.838 393.745 454.711 1.00 57.82  ? 153 HIS C CG  1 
ATOM 6443 N ND1 . HIS E 5 153 ? 362.495 394.034 454.687 1.00 57.82  ? 153 HIS C ND1 1 
ATOM 6444 C CD2 . HIS E 5 153 ? 364.412 394.554 453.794 1.00 57.82  ? 153 HIS C CD2 1 
ATOM 6445 C CE1 . HIS E 5 153 ? 362.266 394.980 453.796 1.00 57.82  ? 153 HIS C CE1 1 
ATOM 6446 N NE2 . HIS E 5 153 ? 363.413 395.312 453.239 1.00 57.82  ? 153 HIS C NE2 1 
ATOM 6447 N N   . VAL E 5 154 ? 362.701 390.290 455.215 1.00 55.95  ? 154 VAL C N   1 
ATOM 6448 C CA  . VAL E 5 154 ? 361.341 389.856 454.902 1.00 55.95  ? 154 VAL C CA  1 
ATOM 6449 C C   . VAL E 5 154 ? 360.424 390.473 455.945 1.00 55.95  ? 154 VAL C C   1 
ATOM 6450 O O   . VAL E 5 154 ? 360.709 390.392 457.142 1.00 55.95  ? 154 VAL C O   1 
ATOM 6451 C CB  . VAL E 5 154 ? 361.167 388.326 454.916 1.00 55.95  ? 154 VAL C CB  1 
ATOM 6452 C CG1 . VAL E 5 154 ? 359.820 387.961 454.365 1.00 55.95  ? 154 VAL C CG1 1 
ATOM 6453 C CG2 . VAL E 5 154 ? 362.231 387.622 454.110 1.00 55.95  ? 154 VAL C CG2 1 
ATOM 6454 N N   . ILE E 5 155 ? 359.339 391.093 455.511 1.00 55.84  ? 155 ILE C N   1 
ATOM 6455 C CA  . ILE E 5 155 ? 358.328 391.592 456.433 1.00 55.84  ? 155 ILE C CA  1 
ATOM 6456 C C   . ILE E 5 155 ? 357.267 390.525 456.617 1.00 55.84  ? 155 ILE C C   1 
ATOM 6457 O O   . ILE E 5 155 ? 356.601 390.126 455.658 1.00 55.84  ? 155 ILE C O   1 
ATOM 6458 C CB  . ILE E 5 155 ? 357.711 392.897 455.928 1.00 55.84  ? 155 ILE C CB  1 
ATOM 6459 C CG1 . ILE E 5 155 ? 358.804 393.934 455.735 1.00 55.84  ? 155 ILE C CG1 1 
ATOM 6460 C CG2 . ILE E 5 155 ? 356.694 393.385 456.913 1.00 55.84  ? 155 ILE C CG2 1 
ATOM 6461 C CD1 . ILE E 5 155 ? 358.299 395.293 455.380 1.00 55.84  ? 155 ILE C CD1 1 
ATOM 6462 N N   . TRP E 5 156 ? 357.095 390.078 457.849 1.00 58.15  ? 156 TRP C N   1 
ATOM 6463 C CA  . TRP E 5 156 ? 356.299 388.903 458.171 1.00 58.15  ? 156 TRP C CA  1 
ATOM 6464 C C   . TRP E 5 156 ? 355.015 389.363 458.845 1.00 58.15  ? 156 TRP C C   1 
ATOM 6465 O O   . TRP E 5 156 ? 355.021 389.709 460.028 1.00 58.15  ? 156 TRP C O   1 
ATOM 6466 C CB  . TRP E 5 156 ? 357.110 387.970 459.063 1.00 58.15  ? 156 TRP C CB  1 
ATOM 6467 C CG  . TRP E 5 156 ? 356.433 386.725 459.491 1.00 58.15  ? 156 TRP C CG  1 
ATOM 6468 C CD1 . TRP E 5 156 ? 355.399 386.097 458.884 1.00 58.15  ? 156 TRP C CD1 1 
ATOM 6469 C CD2 . TRP E 5 156 ? 356.762 385.938 460.634 1.00 58.15  ? 156 TRP C CD2 1 
ATOM 6470 N NE1 . TRP E 5 156 ? 355.054 384.974 459.582 1.00 58.15  ? 156 TRP C NE1 1 
ATOM 6471 C CE2 . TRP E 5 156 ? 355.880 384.858 460.663 1.00 58.15  ? 156 TRP C CE2 1 
ATOM 6472 C CE3 . TRP E 5 156 ? 357.719 386.050 461.638 1.00 58.15  ? 156 TRP C CE3 1 
ATOM 6473 C CZ2 . TRP E 5 156 ? 355.924 383.905 461.649 1.00 58.15  ? 156 TRP C CZ2 1 
ATOM 6474 C CZ3 . TRP E 5 156 ? 357.759 385.107 462.608 1.00 58.15  ? 156 TRP C CZ3 1 
ATOM 6475 C CH2 . TRP E 5 156 ? 356.871 384.047 462.612 1.00 58.15  ? 156 TRP C CH2 1 
ATOM 6476 N N   . ASP E 5 157 ? 353.920 389.366 458.095 1.00 62.91  ? 157 ASP C N   1 
ATOM 6477 C CA  . ASP E 5 157 ? 352.615 389.689 458.644 1.00 62.91  ? 157 ASP C CA  1 
ATOM 6478 C C   . ASP E 5 157 ? 352.059 388.452 459.320 1.00 62.91  ? 157 ASP C C   1 
ATOM 6479 O O   . ASP E 5 157 ? 351.802 387.440 458.666 1.00 62.91  ? 157 ASP C O   1 
ATOM 6480 C CB  . ASP E 5 157 ? 351.656 390.161 457.557 1.00 62.91  ? 157 ASP C CB  1 
ATOM 6481 C CG  . ASP E 5 157 ? 350.453 390.904 458.112 1.00 62.91  ? 157 ASP C CG  1 
ATOM 6482 O OD1 . ASP E 5 157 ? 350.252 390.917 459.342 1.00 62.91  ? 157 ASP C OD1 1 
ATOM 6483 O OD2 . ASP E 5 157 ? 349.697 391.483 457.309 1.00 62.91  ? 157 ASP C OD2 1 
ATOM 6484 N N   . VAL E 5 158 ? 351.858 388.551 460.627 1.00 61.65  ? 158 VAL C N   1 
ATOM 6485 C CA  . VAL E 5 158 ? 351.423 387.418 461.426 1.00 61.65  ? 158 VAL C CA  1 
ATOM 6486 C C   . VAL E 5 158 ? 349.959 387.088 461.180 1.00 61.65  ? 158 VAL C C   1 
ATOM 6487 O O   . VAL E 5 158 ? 349.590 385.912 461.109 1.00 61.65  ? 158 VAL C O   1 
ATOM 6488 C CB  . VAL E 5 158 ? 351.728 387.744 462.892 1.00 61.65  ? 158 VAL C CB  1 
ATOM 6489 C CG1 . VAL E 5 158 ? 350.923 386.924 463.813 1.00 61.65  ? 158 VAL C CG1 1 
ATOM 6490 C CG2 . VAL E 5 158 ? 353.185 387.511 463.155 1.00 61.65  ? 158 VAL C CG2 1 
ATOM 6491 N N   . GLY E 5 159 ? 349.115 388.101 460.987 1.00 64.82  ? 159 GLY C N   1 
ATOM 6492 C CA  . GLY E 5 159 ? 347.700 387.854 460.783 1.00 64.82  ? 159 GLY C CA  1 
ATOM 6493 C C   . GLY E 5 159 ? 347.376 387.165 459.473 1.00 64.82  ? 159 GLY C C   1 
ATOM 6494 O O   . GLY E 5 159 ? 346.341 386.507 459.358 1.00 64.82  ? 159 GLY C O   1 
ATOM 6495 N N   . LEU E 5 160 ? 348.248 387.290 458.476 1.00 66.68  ? 160 LEU C N   1 
ATOM 6496 C CA  . LEU E 5 160 ? 347.995 386.616 457.208 1.00 66.68  ? 160 LEU C CA  1 
ATOM 6497 C C   . LEU E 5 160 ? 348.419 385.160 457.275 1.00 66.68  ? 160 LEU C C   1 
ATOM 6498 O O   . LEU E 5 160 ? 347.594 384.253 457.139 1.00 66.68  ? 160 LEU C O   1 
ATOM 6499 C CB  . LEU E 5 160 ? 348.725 387.322 456.069 1.00 66.68  ? 160 LEU C CB  1 
ATOM 6500 C CG  . LEU E 5 160 ? 348.339 388.752 455.713 1.00 66.68  ? 160 LEU C CG  1 
ATOM 6501 C CD1 . LEU E 5 160 ? 348.761 389.030 454.291 1.00 66.68  ? 160 LEU C CD1 1 
ATOM 6502 C CD2 . LEU E 5 160 ? 346.851 388.996 455.880 1.00 66.68  ? 160 LEU C CD2 1 
ATOM 6503 N N   . GLN E 5 161 ? 349.703 384.919 457.491 1.00 67.84  ? 161 GLN C N   1 
ATOM 6504 C CA  . GLN E 5 161 ? 350.233 383.574 457.596 1.00 67.84  ? 161 GLN C CA  1 
ATOM 6505 C C   . GLN E 5 161 ? 351.009 383.441 458.890 1.00 67.84  ? 161 GLN C C   1 
ATOM 6506 O O   . GLN E 5 161 ? 351.500 384.422 459.447 1.00 67.84  ? 161 GLN C O   1 
ATOM 6507 C CB  . GLN E 5 161 ? 351.135 383.239 456.419 1.00 67.84  ? 161 GLN C CB  1 
ATOM 6508 C CG  . GLN E 5 161 ? 352.291 384.177 456.270 1.00 67.84  ? 161 GLN C CG  1 
ATOM 6509 C CD  . GLN E 5 161 ? 352.978 383.996 454.952 1.00 67.84  ? 161 GLN C CD  1 
ATOM 6510 O OE1 . GLN E 5 161 ? 352.647 383.089 454.192 1.00 67.84  ? 161 GLN C OE1 1 
ATOM 6511 N NE2 . GLN E 5 161 ? 353.943 384.855 454.664 1.00 67.84  ? 161 GLN C NE2 1 
ATOM 6512 N N   . SER E 5 162 ? 351.122 382.208 459.366 1.00 63.81  ? 162 SER C N   1 
ATOM 6513 C CA  . SER E 5 162 ? 351.764 381.941 460.642 1.00 63.81  ? 162 SER C CA  1 
ATOM 6514 C C   . SER E 5 162 ? 353.092 381.213 460.486 1.00 63.81  ? 162 SER C C   1 
ATOM 6515 O O   . SER E 5 162 ? 353.503 380.496 461.398 1.00 63.81  ? 162 SER C O   1 
ATOM 6516 C CB  . SER E 5 162 ? 350.819 381.148 461.539 1.00 63.81  ? 162 SER C CB  1 
ATOM 6517 O OG  . SER E 5 162 ? 350.125 380.169 460.793 1.00 63.81  ? 162 SER C OG  1 
ATOM 6518 N N   . SER E 5 163 ? 353.781 381.403 459.363 1.00 65.33  ? 163 SER C N   1 
ATOM 6519 C CA  . SER E 5 163 ? 355.036 380.708 459.095 1.00 65.33  ? 163 SER C CA  1 
ATOM 6520 C C   . SER E 5 163 ? 355.779 381.448 457.999 1.00 65.33  ? 163 SER C C   1 
ATOM 6521 O O   . SER E 5 163 ? 355.214 381.679 456.930 1.00 65.33  ? 163 SER C O   1 
ATOM 6522 C CB  . SER E 5 163 ? 354.771 379.278 458.676 1.00 65.33  ? 163 SER C CB  1 
ATOM 6523 O OG  . SER E 5 163 ? 353.672 379.231 457.789 1.00 65.33  ? 163 SER C OG  1 
ATOM 6524 N N   . CYS E 5 164 ? 357.039 381.801 458.240 1.00 63.25  ? 164 CYS C N   1 
ATOM 6525 C CA  . CYS E 5 164 ? 357.833 382.547 457.271 1.00 63.25  ? 164 CYS C CA  1 
ATOM 6526 C C   . CYS E 5 164 ? 359.205 381.915 457.148 1.00 63.25  ? 164 CYS C C   1 
ATOM 6527 O O   . CYS E 5 164 ? 359.847 381.630 458.160 1.00 63.25  ? 164 CYS C O   1 
ATOM 6528 C CB  . CYS E 5 164 ? 357.968 384.010 457.675 1.00 63.25  ? 164 CYS C CB  1 
ATOM 6529 S SG  . CYS E 5 164 ? 359.079 384.949 456.638 1.00 63.25  ? 164 CYS C SG  1 
ATOM 6530 N N   . VAL E 5 165 ? 359.663 381.733 455.913 1.00 62.29  ? 165 VAL C N   1 
ATOM 6531 C CA  . VAL E 5 165 ? 360.886 381.002 455.604 1.00 62.29  ? 165 VAL C CA  1 
ATOM 6532 C C   . VAL E 5 165 ? 361.947 381.996 455.147 1.00 62.29  ? 165 VAL C C   1 
ATOM 6533 O O   . VAL E 5 165 ? 361.645 382.942 454.412 1.00 62.29  ? 165 VAL C O   1 
ATOM 6534 C CB  . VAL E 5 165 ? 360.615 379.936 454.529 1.00 62.29  ? 165 VAL C CB  1 
ATOM 6535 C CG1 . VAL E 5 165 ? 361.815 379.069 454.288 1.00 62.29  ? 165 VAL C CG1 1 
ATOM 6536 C CG2 . VAL E 5 165 ? 359.457 379.090 454.944 1.00 62.29  ? 165 VAL C CG2 1 
ATOM 6537 N N   . LEU E 5 166 ? 363.187 381.789 455.585 1.00 62.92  ? 166 LEU C N   1 
ATOM 6538 C CA  . LEU E 5 166 ? 364.303 382.659 455.248 1.00 62.92  ? 166 LEU C CA  1 
ATOM 6539 C C   . LEU E 5 166 ? 365.545 381.811 455.017 1.00 62.92  ? 166 LEU C C   1 
ATOM 6540 O O   . LEU E 5 166 ? 366.001 381.125 455.933 1.00 62.92  ? 166 LEU C O   1 
ATOM 6541 C CB  . LEU E 5 166 ? 364.539 383.661 456.372 1.00 62.92  ? 166 LEU C CB  1 
ATOM 6542 C CG  . LEU E 5 166 ? 365.813 384.489 456.351 1.00 62.92  ? 166 LEU C CG  1 
ATOM 6543 C CD1 . LEU E 5 166 ? 365.714 385.601 455.331 1.00 62.92  ? 166 LEU C CD1 1 
ATOM 6544 C CD2 . LEU E 5 166 ? 366.058 385.047 457.723 1.00 62.92  ? 166 LEU C CD2 1 
ATOM 6545 N N   . CYS E 5 167 ? 366.098 381.862 453.809 1.00 65.96  ? 167 CYS C N   1 
ATOM 6546 C CA  . CYS E 5 167 ? 367.192 380.986 453.409 1.00 65.96  ? 167 CYS C CA  1 
ATOM 6547 C C   . CYS E 5 167 ? 368.513 381.742 453.304 1.00 65.96  ? 167 CYS C C   1 
ATOM 6548 O O   . CYS E 5 167 ? 368.643 382.667 452.501 1.00 65.96  ? 167 CYS C O   1 
ATOM 6549 C CB  . CYS E 5 167 ? 366.882 380.318 452.075 1.00 65.96  ? 167 CYS C CB  1 
ATOM 6550 S SG  . CYS E 5 167 ? 368.192 379.268 451.468 1.00 65.96  ? 167 CYS C SG  1 
ATOM 6551 N N   . VAL E 5 168 ? 369.498 381.332 454.102 1.00 62.35  ? 168 VAL C N   1 
ATOM 6552 C CA  . VAL E 5 168 ? 370.798 382.001 454.175 1.00 62.35  ? 168 VAL C CA  1 
ATOM 6553 C C   . VAL E 5 168 ? 371.897 381.000 453.841 1.00 62.35  ? 168 VAL C C   1 
ATOM 6554 O O   . VAL E 5 168 ? 371.648 379.790 453.877 1.00 62.35  ? 168 VAL C O   1 
ATOM 6555 C CB  . VAL E 5 168 ? 371.035 382.619 455.562 1.00 62.35  ? 168 VAL C CB  1 
ATOM 6556 C CG1 . VAL E 5 168 ? 369.896 383.517 455.961 1.00 62.35  ? 168 VAL C CG1 1 
ATOM 6557 C CG2 . VAL E 5 168 ? 371.229 381.553 456.592 1.00 62.35  ? 168 VAL C CG2 1 
ATOM 6558 N N   . PRO E 5 169 ? 373.099 381.436 453.466 1.00 61.86  ? 169 PRO C N   1 
ATOM 6559 C CA  . PRO E 5 169 ? 374.207 380.488 453.319 1.00 61.86  ? 169 PRO C CA  1 
ATOM 6560 C C   . PRO E 5 169 ? 375.089 380.415 454.558 1.00 61.86  ? 169 PRO C C   1 
ATOM 6561 O O   . PRO E 5 169 ? 375.281 381.398 455.273 1.00 61.86  ? 169 PRO C O   1 
ATOM 6562 C CB  . PRO E 5 169 ? 374.981 381.042 452.121 1.00 61.86  ? 169 PRO C CB  1 
ATOM 6563 C CG  . PRO E 5 169 ? 374.740 382.476 452.177 1.00 61.86  ? 169 PRO C CG  1 
ATOM 6564 C CD  . PRO E 5 169 ? 373.357 382.675 452.715 1.00 61.86  ? 169 PRO C CD  1 
ATOM 6565 N N   . TRP E 5 170 ? 375.654 379.230 454.786 1.00 57.96  ? 170 TRP C N   1 
ATOM 6566 C CA  . TRP E 5 170 ? 376.466 378.934 455.960 1.00 57.96  ? 170 TRP C CA  1 
ATOM 6567 C C   . TRP E 5 170 ? 377.715 378.189 455.523 1.00 57.96  ? 170 TRP C C   1 
ATOM 6568 O O   . TRP E 5 170 ? 377.621 377.082 454.991 1.00 57.96  ? 170 TRP C O   1 
ATOM 6569 C CB  . TRP E 5 170 ? 375.678 378.084 456.949 1.00 57.96  ? 170 TRP C CB  1 
ATOM 6570 C CG  . TRP E 5 170 ? 376.122 378.087 458.364 1.00 57.96  ? 170 TRP C CG  1 
ATOM 6571 C CD1 . TRP E 5 170 ? 376.785 379.066 459.013 1.00 57.96  ? 170 TRP C CD1 1 
ATOM 6572 C CD2 . TRP E 5 170 ? 375.902 377.049 459.320 1.00 57.96  ? 170 TRP C CD2 1 
ATOM 6573 N NE1 . TRP E 5 170 ? 377.005 378.706 460.314 1.00 57.96  ? 170 TRP C NE1 1 
ATOM 6574 C CE2 . TRP E 5 170 ? 376.472 377.466 460.524 1.00 57.96  ? 170 TRP C CE2 1 
ATOM 6575 C CE3 . TRP E 5 170 ? 375.284 375.801 459.265 1.00 57.96  ? 170 TRP C CE3 1 
ATOM 6576 C CZ2 . TRP E 5 170 ? 376.444 376.687 461.664 1.00 57.96  ? 170 TRP C CZ2 1 
ATOM 6577 C CZ3 . TRP E 5 170 ? 375.256 375.030 460.392 1.00 57.96  ? 170 TRP C CZ3 1 
ATOM 6578 C CH2 . TRP E 5 170 ? 375.831 375.472 461.578 1.00 57.96  ? 170 TRP C CH2 1 
ATOM 6579 N N   . ILE E 5 171 ? 378.881 378.789 455.745 1.00 59.16  ? 171 ILE C N   1 
ATOM 6580 C CA  . ILE E 5 171 ? 380.149 378.241 455.291 1.00 59.16  ? 171 ILE C CA  1 
ATOM 6581 C C   . ILE E 5 171 ? 381.016 378.034 456.524 1.00 59.16  ? 171 ILE C C   1 
ATOM 6582 O O   . ILE E 5 171 ? 380.943 378.795 457.490 1.00 59.16  ? 171 ILE C O   1 
ATOM 6583 C CB  . ILE E 5 171 ? 380.850 379.178 454.282 1.00 59.16  ? 171 ILE C CB  1 
ATOM 6584 C CG1 . ILE E 5 171 ? 379.904 379.582 453.158 1.00 59.16  ? 171 ILE C CG1 1 
ATOM 6585 C CG2 . ILE E 5 171 ? 382.031 378.509 453.620 1.00 59.16  ? 171 ILE C CG2 1 
ATOM 6586 C CD1 . ILE E 5 171 ? 379.336 378.438 452.384 1.00 59.16  ? 171 ILE C CD1 1 
ATOM 6587 N N   . SER E 5 172 ? 381.816 376.972 456.501 1.00 57.83  ? 172 SER C N   1 
ATOM 6588 C CA  . SER E 5 172 ? 382.811 376.733 457.534 1.00 57.83  ? 172 SER C CA  1 
ATOM 6589 C C   . SER E 5 172 ? 383.851 377.845 457.558 1.00 57.83  ? 172 SER C C   1 
ATOM 6590 O O   . SER E 5 172 ? 384.988 377.642 457.971 1.00 57.83  ? 172 SER C O   1 
ATOM 6591 C CB  . SER E 5 172 ? 383.492 375.392 457.309 1.00 57.83  ? 172 SER C CB  1 
ATOM 6592 O OG  . SER E 5 172 ? 384.317 375.061 458.404 1.00 57.83  ? 172 SER C OG  1 
ATOM 6593 N N   . ALA E 5 186 ? 383.203 388.780 461.819 1.00 65.00  ? 186 ALA C N   1 
ATOM 6594 C CA  . ALA E 5 186 ? 381.826 388.807 461.355 1.00 65.00  ? 186 ALA C CA  1 
ATOM 6595 C C   . ALA E 5 186 ? 381.617 387.768 460.256 1.00 65.00  ? 186 ALA C C   1 
ATOM 6596 O O   . ALA E 5 186 ? 382.352 387.720 459.275 1.00 65.00  ? 186 ALA C O   1 
ATOM 6597 C CB  . ALA E 5 186 ? 381.454 390.200 460.867 1.00 65.00  ? 186 ALA C CB  1 
ATOM 6598 N N   . ALA E 5 187 ? 380.609 386.923 460.454 1.00 61.61  ? 187 ALA C N   1 
ATOM 6599 C CA  . ALA E 5 187 ? 380.240 385.913 459.479 1.00 61.61  ? 187 ALA C CA  1 
ATOM 6600 C C   . ALA E 5 187 ? 378.761 385.933 459.140 1.00 61.61  ? 187 ALA C C   1 
ATOM 6601 O O   . ALA E 5 187 ? 378.351 385.225 458.219 1.00 61.61  ? 187 ALA C O   1 
ATOM 6602 C CB  . ALA E 5 187 ? 380.616 384.521 459.986 1.00 61.61  ? 187 ALA C CB  1 
ATOM 6603 N N   . GLY E 5 188 ? 377.955 386.717 459.840 1.00 61.78  ? 188 GLY C N   1 
ATOM 6604 C CA  . GLY E 5 188 ? 376.537 386.817 459.568 1.00 61.78  ? 188 GLY C CA  1 
ATOM 6605 C C   . GLY E 5 188 ? 375.741 387.027 460.838 1.00 61.78  ? 188 GLY C C   1 
ATOM 6606 O O   . GLY E 5 188 ? 376.222 386.835 461.951 1.00 61.78  ? 188 GLY C O   1 
ATOM 6607 N N   . TYR E 5 189 ? 374.491 387.427 460.640 1.00 60.94  ? 189 TYR C N   1 
ATOM 6608 C CA  . TYR E 5 189 ? 373.571 387.668 461.736 1.00 60.94  ? 189 TYR C CA  1 
ATOM 6609 C C   . TYR E 5 189 ? 372.158 387.452 461.227 1.00 60.94  ? 189 TYR C C   1 
ATOM 6610 O O   . TYR E 5 189 ? 371.863 387.733 460.067 1.00 60.94  ? 189 TYR C O   1 
ATOM 6611 C CB  . TYR E 5 189 ? 373.706 389.080 462.282 1.00 60.94  ? 189 TYR C CB  1 
ATOM 6612 C CG  . TYR E 5 189 ? 374.816 389.286 463.260 1.00 60.94  ? 189 TYR C CG  1 
ATOM 6613 C CD1 . TYR E 5 189 ? 374.661 388.939 464.583 1.00 60.94  ? 189 TYR C CD1 1 
ATOM 6614 C CD2 . TYR E 5 189 ? 376.007 389.862 462.868 1.00 60.94  ? 189 TYR C CD2 1 
ATOM 6615 C CE1 . TYR E 5 189 ? 375.666 389.142 465.488 1.00 60.94  ? 189 TYR C CE1 1 
ATOM 6616 C CE2 . TYR E 5 189 ? 377.021 390.070 463.763 1.00 60.94  ? 189 TYR C CE2 1 
ATOM 6617 C CZ  . TYR E 5 189 ? 376.844 389.710 465.073 1.00 60.94  ? 189 TYR C CZ  1 
ATOM 6618 O OH  . TYR E 5 189 ? 377.852 389.912 465.980 1.00 60.94  ? 189 TYR C OH  1 
ATOM 6619 N N   . VAL E 5 190 ? 371.291 386.920 462.089 1.00 57.58  ? 190 VAL C N   1 
ATOM 6620 C CA  . VAL E 5 190 ? 369.916 386.618 461.701 1.00 57.58  ? 190 VAL C CA  1 
ATOM 6621 C C   . VAL E 5 190 ? 368.945 387.341 462.630 1.00 57.58  ? 190 VAL C C   1 
ATOM 6622 O O   . VAL E 5 190 ? 367.993 386.735 463.128 1.00 57.58  ? 190 VAL C O   1 
ATOM 6623 C CB  . VAL E 5 190 ? 369.625 385.105 461.678 1.00 57.58  ? 190 VAL C CB  1 
ATOM 6624 C CG1 . VAL E 5 190 ? 368.544 384.788 460.656 1.00 57.58  ? 190 VAL C CG1 1 
ATOM 6625 C CG2 . VAL E 5 190 ? 370.849 384.299 461.377 1.00 57.58  ? 190 VAL C CG2 1 
ATOM 6626 N N   . THR E 5 191 ? 369.230 388.598 462.961 1.00 58.55  ? 191 THR C N   1 
ATOM 6627 C CA  . THR E 5 191 ? 368.387 389.368 463.874 1.00 58.55  ? 191 THR C CA  1 
ATOM 6628 C C   . THR E 5 191 ? 366.960 389.541 463.350 1.00 58.55  ? 191 THR C C   1 
ATOM 6629 O O   . THR E 5 191 ? 366.692 389.410 462.157 1.00 58.55  ? 191 THR C O   1 
ATOM 6630 C CB  . THR E 5 191 ? 368.993 390.745 464.110 1.00 58.55  ? 191 THR C CB  1 
ATOM 6631 O OG1 . THR E 5 191 ? 368.648 391.599 463.020 1.00 58.55  ? 191 THR C OG1 1 
ATOM 6632 C CG2 . THR E 5 191 ? 370.487 390.657 464.184 1.00 58.55  ? 191 THR C CG2 1 
ATOM 6633 N N   . CYS E 5 192 ? 366.037 389.840 464.268 1.00 59.23  ? 192 CYS C N   1 
ATOM 6634 C CA  . CYS E 5 192 ? 364.624 390.029 463.961 1.00 59.23  ? 192 CYS C CA  1 
ATOM 6635 C C   . CYS E 5 192 ? 364.042 391.139 464.821 1.00 59.23  ? 192 CYS C C   1 
ATOM 6636 O O   . CYS E 5 192 ? 364.384 391.258 465.998 1.00 59.23  ? 192 CYS C O   1 
ATOM 6637 C CB  . CYS E 5 192 ? 363.846 388.748 464.182 1.00 59.23  ? 192 CYS C CB  1 
ATOM 6638 S SG  . CYS E 5 192 ? 362.064 388.906 464.275 1.00 59.23  ? 192 CYS C SG  1 
ATOM 6639 N N   . TRP E 5 193 ? 363.137 391.933 464.240 1.00 59.78  ? 193 TRP C N   1 
ATOM 6640 C CA  . TRP E 5 193 ? 362.735 393.213 464.809 1.00 59.78  ? 193 TRP C CA  1 
ATOM 6641 C C   . TRP E 5 193 ? 361.223 393.387 464.829 1.00 59.78  ? 193 TRP C C   1 
ATOM 6642 O O   . TRP E 5 193 ? 360.518 392.902 463.945 1.00 59.78  ? 193 TRP C O   1 
ATOM 6643 C CB  . TRP E 5 193 ? 363.327 394.367 464.019 1.00 59.78  ? 193 TRP C CB  1 
ATOM 6644 C CG  . TRP E 5 193 ? 364.793 394.358 463.952 1.00 59.78  ? 193 TRP C CG  1 
ATOM 6645 C CD1 . TRP E 5 193 ? 365.566 393.652 463.097 1.00 59.78  ? 193 TRP C CD1 1 
ATOM 6646 C CD2 . TRP E 5 193 ? 365.680 395.111 464.767 1.00 59.78  ? 193 TRP C CD2 1 
ATOM 6647 N NE1 . TRP E 5 193 ? 366.886 393.904 463.336 1.00 59.78  ? 193 TRP C NE1 1 
ATOM 6648 C CE2 . TRP E 5 193 ? 366.979 394.803 464.361 1.00 59.78  ? 193 TRP C CE2 1 
ATOM 6649 C CE3 . TRP E 5 193 ? 365.499 396.016 465.809 1.00 59.78  ? 193 TRP C CE3 1 
ATOM 6650 C CZ2 . TRP E 5 193 ? 368.085 395.361 464.955 1.00 59.78  ? 193 TRP C CZ2 1 
ATOM 6651 C CZ3 . TRP E 5 193 ? 366.594 396.565 466.392 1.00 59.78  ? 193 TRP C CZ3 1 
ATOM 6652 C CH2 . TRP E 5 193 ? 367.871 396.242 465.967 1.00 59.78  ? 193 TRP C CH2 1 
ATOM 6653 N N   . TYR E 5 194 ? 360.736 394.118 465.830 1.00 63.11  ? 194 TYR C N   1 
ATOM 6654 C CA  . TYR E 5 194 ? 359.336 394.527 465.867 1.00 63.11  ? 194 TYR C CA  1 
ATOM 6655 C C   . TYR E 5 194 ? 359.079 395.627 464.849 1.00 63.11  ? 194 TYR C C   1 
ATOM 6656 O O   . TYR E 5 194 ? 359.606 396.732 464.978 1.00 63.11  ? 194 TYR C O   1 
ATOM 6657 C CB  . TYR E 5 194 ? 358.960 395.064 467.244 1.00 63.11  ? 194 TYR C CB  1 
ATOM 6658 C CG  . TYR E 5 194 ? 358.739 394.057 468.329 1.00 63.11  ? 194 TYR C CG  1 
ATOM 6659 C CD1 . TYR E 5 194 ? 357.590 393.298 468.378 1.00 63.11  ? 194 TYR C CD1 1 
ATOM 6660 C CD2 . TYR E 5 194 ? 359.666 393.898 469.333 1.00 63.11  ? 194 TYR C CD2 1 
ATOM 6661 C CE1 . TYR E 5 194 ? 357.392 392.388 469.386 1.00 63.11  ? 194 TYR C CE1 1 
ATOM 6662 C CE2 . TYR E 5 194 ? 359.476 392.995 470.337 1.00 63.11  ? 194 TYR C CE2 1 
ATOM 6663 C CZ  . TYR E 5 194 ? 358.344 392.246 470.358 1.00 63.11  ? 194 TYR C CZ  1 
ATOM 6664 O OH  . TYR E 5 194 ? 358.174 391.351 471.373 1.00 63.11  ? 194 TYR C OH  1 
ATOM 6665 N N   . GLN E 5 195 ? 358.239 395.353 463.861 1.00 61.27  ? 195 GLN C N   1 
ATOM 6666 C CA  . GLN E 5 195 ? 357.807 396.427 462.978 1.00 61.27  ? 195 GLN C CA  1 
ATOM 6667 C C   . GLN E 5 195 ? 356.642 397.189 463.595 1.00 61.27  ? 195 GLN C C   1 
ATOM 6668 O O   . GLN E 5 195 ? 356.707 398.410 463.751 1.00 61.27  ? 195 GLN C O   1 
ATOM 6669 C CB  . GLN E 5 195 ? 357.433 395.873 461.607 1.00 61.27  ? 195 GLN C CB  1 
ATOM 6670 C CG  . GLN E 5 195 ? 356.671 396.835 460.739 1.00 61.27  ? 195 GLN C CG  1 
ATOM 6671 C CD  . GLN E 5 195 ? 357.568 397.790 460.006 1.00 61.27  ? 195 GLN C CD  1 
ATOM 6672 O OE1 . GLN E 5 195 ? 358.782 397.658 460.035 1.00 61.27  ? 195 GLN C OE1 1 
ATOM 6673 N NE2 . GLN E 5 195 ? 356.974 398.757 459.329 1.00 61.27  ? 195 GLN C NE2 1 
ATOM 6674 N N   . THR E 5 196 ? 355.567 396.485 463.941 1.00 61.48  ? 196 THR C N   1 
ATOM 6675 C CA  . THR E 5 196 ? 354.455 397.040 464.696 1.00 61.48  ? 196 THR C CA  1 
ATOM 6676 C C   . THR E 5 196 ? 354.263 396.210 465.955 1.00 61.48  ? 196 THR C C   1 
ATOM 6677 O O   . THR E 5 196 ? 354.861 395.148 466.115 1.00 61.48  ? 196 THR C O   1 
ATOM 6678 C CB  . THR E 5 196 ? 353.157 397.038 463.890 1.00 61.48  ? 196 THR C CB  1 
ATOM 6679 O OG1 . THR E 5 196 ? 352.764 395.690 463.642 1.00 61.48  ? 196 THR C OG1 1 
ATOM 6680 C CG2 . THR E 5 196 ? 353.346 397.724 462.566 1.00 61.48  ? 196 THR C CG2 1 
ATOM 6681 N N   . ASN E 5 197 ? 353.400 396.678 466.844 1.00 63.87  ? 197 ASN C N   1 
ATOM 6682 C CA  . ASN E 5 197 ? 353.132 395.945 468.070 1.00 63.87  ? 197 ASN C CA  1 
ATOM 6683 C C   . ASN E 5 197 ? 352.175 394.787 467.814 1.00 63.87  ? 197 ASN C C   1 
ATOM 6684 O O   . ASN E 5 197 ? 351.739 394.534 466.691 1.00 63.87  ? 197 ASN C O   1 
ATOM 6685 C CB  . ASN E 5 197 ? 352.568 396.873 469.135 1.00 63.87  ? 197 ASN C CB  1 
ATOM 6686 C CG  . ASN E 5 197 ? 353.641 397.609 469.866 1.00 63.87  ? 197 ASN C CG  1 
ATOM 6687 O OD1 . ASN E 5 197 ? 354.775 397.154 469.923 1.00 63.87  ? 197 ASN C OD1 1 
ATOM 6688 N ND2 . ASN E 5 197 ? 353.302 398.759 470.425 1.00 63.87  ? 197 ASN C ND2 1 
ATOM 6689 N N   . ILE E 5 198 ? 351.842 394.071 468.884 1.00 62.25  ? 198 ILE C N   1 
ATOM 6690 C CA  . ILE E 5 198 ? 350.898 392.965 468.822 1.00 62.25  ? 198 ILE C CA  1 
ATOM 6691 C C   . ILE E 5 198 ? 349.544 393.514 469.253 1.00 62.25  ? 198 ILE C C   1 
ATOM 6692 O O   . ILE E 5 198 ? 349.335 393.846 470.418 1.00 62.25  ? 198 ILE C O   1 
ATOM 6693 C CB  . ILE E 5 198 ? 351.344 391.794 469.694 1.00 62.25  ? 198 ILE C CB  1 
ATOM 6694 C CG1 . ILE E 5 198 ? 352.623 391.182 469.140 1.00 62.25  ? 198 ILE C CG1 1 
ATOM 6695 C CG2 . ILE E 5 198 ? 350.264 390.747 469.772 1.00 62.25  ? 198 ILE C CG2 1 
ATOM 6696 C CD1 . ILE E 5 198 ? 352.441 390.445 467.847 1.00 62.25  ? 198 ILE C CD1 1 
ATOM 6697 N N   . VAL E 5 199 ? 348.630 393.635 468.304 1.00 62.10  ? 199 VAL C N   1 
ATOM 6698 C CA  . VAL E 5 199 ? 347.291 394.128 468.592 1.00 62.10  ? 199 VAL C CA  1 
ATOM 6699 C C   . VAL E 5 199 ? 346.410 392.937 468.919 1.00 62.10  ? 199 VAL C C   1 
ATOM 6700 O O   . VAL E 5 199 ? 346.393 391.949 468.182 1.00 62.10  ? 199 VAL C O   1 
ATOM 6701 C CB  . VAL E 5 199 ? 346.741 394.920 467.401 1.00 62.10  ? 199 VAL C CB  1 
ATOM 6702 C CG1 . VAL E 5 199 ? 345.323 395.338 467.645 1.00 62.10  ? 199 VAL C CG1 1 
ATOM 6703 C CG2 . VAL E 5 199 ? 347.600 396.126 467.141 1.00 62.10  ? 199 VAL C CG2 1 
ATOM 6704 N N   . VAL E 5 200 ? 345.678 393.019 470.023 1.00 60.49  ? 200 VAL C N   1 
ATOM 6705 C CA  . VAL E 5 200 ? 344.991 391.844 470.538 1.00 60.49  ? 200 VAL C CA  1 
ATOM 6706 C C   . VAL E 5 200 ? 343.610 392.280 471.024 1.00 60.49  ? 200 VAL C C   1 
ATOM 6707 O O   . VAL E 5 200 ? 343.447 393.431 471.451 1.00 60.49  ? 200 VAL C O   1 
ATOM 6708 C CB  . VAL E 5 200 ? 345.857 391.173 471.622 1.00 60.49  ? 200 VAL C CB  1 
ATOM 6709 C CG1 . VAL E 5 200 ? 345.783 391.870 472.970 1.00 60.49  ? 200 VAL C CG1 1 
ATOM 6710 C CG2 . VAL E 5 200 ? 345.590 389.721 471.723 1.00 60.49  ? 200 VAL C CG2 1 
ATOM 6711 N N   . PRO E 5 201 ? 342.571 391.454 470.904 1.00 59.07  ? 201 PRO C N   1 
ATOM 6712 C CA  . PRO E 5 201 ? 341.263 391.858 471.424 1.00 59.07  ? 201 PRO C CA  1 
ATOM 6713 C C   . PRO E 5 201 ? 341.156 391.728 472.927 1.00 59.07  ? 201 PRO C C   1 
ATOM 6714 O O   . PRO E 5 201 ? 342.130 391.406 473.609 1.00 59.07  ? 201 PRO C O   1 
ATOM 6715 C CB  . PRO E 5 201 ? 340.295 390.895 470.736 1.00 59.07  ? 201 PRO C CB  1 
ATOM 6716 C CG  . PRO E 5 201 ? 341.010 390.356 469.623 1.00 59.07  ? 201 PRO C CG  1 
ATOM 6717 C CD  . PRO E 5 201 ? 342.438 390.311 469.997 1.00 59.07  ? 201 PRO C CD  1 
ATOM 6718 N N   . ALA E 5 202 ? 339.968 391.982 473.455 1.00 60.96  ? 202 ALA C N   1 
ATOM 6719 C CA  . ALA E 5 202 ? 339.730 391.759 474.866 1.00 60.96  ? 202 ALA C CA  1 
ATOM 6720 C C   . ALA E 5 202 ? 339.638 390.271 475.140 1.00 60.96  ? 202 ALA C C   1 
ATOM 6721 O O   . ALA E 5 202 ? 339.234 389.492 474.276 1.00 60.96  ? 202 ALA C O   1 
ATOM 6722 C CB  . ALA E 5 202 ? 338.446 392.453 475.305 1.00 60.96  ? 202 ALA C CB  1 
ATOM 6723 N N   . ASP E 5 203 ? 340.035 389.888 476.356 1.00 61.61  ? 203 ASP C N   1 
ATOM 6724 C CA  . ASP E 5 203 ? 340.030 388.503 476.843 1.00 61.61  ? 203 ASP C CA  1 
ATOM 6725 C C   . ASP E 5 203 ? 340.901 387.574 475.995 1.00 61.61  ? 203 ASP C C   1 
ATOM 6726 O O   . ASP E 5 203 ? 340.595 386.393 475.849 1.00 61.61  ? 203 ASP C O   1 
ATOM 6727 C CB  . ASP E 5 203 ? 338.604 387.943 476.960 1.00 61.61  ? 203 ASP C CB  1 
ATOM 6728 C CG  . ASP E 5 203 ? 337.735 388.746 477.908 1.00 61.61  ? 203 ASP C CG  1 
ATOM 6729 O OD1 . ASP E 5 203 ? 338.252 389.159 478.961 1.00 61.61  ? 203 ASP C OD1 1 
ATOM 6730 O OD2 . ASP E 5 203 ? 336.537 388.965 477.613 1.00 61.61  ? 203 ASP C OD2 1 
ATOM 6731 N N   . VAL E 5 204 ? 341.997 388.082 475.431 1.00 59.39  ? 204 VAL C N   1 
ATOM 6732 C CA  . VAL E 5 204 ? 343.016 387.269 474.775 1.00 59.39  ? 204 VAL C CA  1 
ATOM 6733 C C   . VAL E 5 204 ? 344.359 387.647 475.381 1.00 59.39  ? 204 VAL C C   1 
ATOM 6734 O O   . VAL E 5 204 ? 344.621 388.827 475.625 1.00 59.39  ? 204 VAL C O   1 
ATOM 6735 C CB  . VAL E 5 204 ? 343.044 387.481 473.248 1.00 59.39  ? 204 VAL C CB  1 
ATOM 6736 C CG1 . VAL E 5 204 ? 343.982 386.515 472.589 1.00 59.39  ? 204 VAL C CG1 1 
ATOM 6737 C CG2 . VAL E 5 204 ? 341.692 387.327 472.644 1.00 59.39  ? 204 VAL C CG2 1 
ATOM 6738 N N   . GLN E 5 205 ? 345.203 386.652 475.644 1.00 63.83  ? 205 GLN C N   1 
ATOM 6739 C CA  . GLN E 5 205 ? 346.515 386.910 476.217 1.00 63.83  ? 205 GLN C CA  1 
ATOM 6740 C C   . GLN E 5 205 ? 347.443 387.545 475.194 1.00 63.83  ? 205 GLN C C   1 
ATOM 6741 O O   . GLN E 5 205 ? 347.343 387.298 473.993 1.00 63.83  ? 205 GLN C O   1 
ATOM 6742 C CB  . GLN E 5 205 ? 347.131 385.619 476.729 1.00 63.83  ? 205 GLN C CB  1 
ATOM 6743 C CG  . GLN E 5 205 ? 346.634 385.216 478.079 1.00 63.83  ? 205 GLN C CG  1 
ATOM 6744 C CD  . GLN E 5 205 ? 347.382 385.897 479.185 1.00 63.83  ? 205 GLN C CD  1 
ATOM 6745 O OE1 . GLN E 5 205 ? 348.482 386.398 478.981 1.00 63.83  ? 205 GLN C OE1 1 
ATOM 6746 N NE2 . GLN E 5 205 ? 346.797 385.914 480.373 1.00 63.83  ? 205 GLN C NE2 1 
ATOM 6747 N N   . SER E 5 206 ? 348.368 388.361 475.686 1.00 66.70  ? 206 SER C N   1 
ATOM 6748 C CA  . SER E 5 206 ? 349.276 389.103 474.825 1.00 66.70  ? 206 SER C CA  1 
ATOM 6749 C C   . SER E 5 206 ? 350.675 388.521 474.751 1.00 66.70  ? 206 SER C C   1 
ATOM 6750 O O   . SER E 5 206 ? 351.432 388.892 473.856 1.00 66.70  ? 206 SER C O   1 
ATOM 6751 C CB  . SER E 5 206 ? 349.372 390.557 475.290 1.00 66.70  ? 206 SER C CB  1 
ATOM 6752 O OG  . SER E 5 206 ? 349.461 390.620 476.697 1.00 66.70  ? 206 SER C OG  1 
ATOM 6753 N N   . SER E 5 207 ? 351.039 387.623 475.658 1.00 65.66  ? 207 SER C N   1 
ATOM 6754 C CA  . SER E 5 207 ? 352.367 387.018 475.655 1.00 65.66  ? 207 SER C CA  1 
ATOM 6755 C C   . SER E 5 207 ? 352.348 385.788 474.760 1.00 65.66  ? 207 SER C C   1 
ATOM 6756 O O   . SER E 5 207 ? 351.834 384.738 475.138 1.00 65.66  ? 207 SER C O   1 
ATOM 6757 C CB  . SER E 5 207 ? 352.790 386.668 477.072 1.00 65.66  ? 207 SER C CB  1 
ATOM 6758 O OG  . SER E 5 207 ? 352.906 387.838 477.853 1.00 65.66  ? 207 SER C OG  1 
ATOM 6759 N N   . CYS E 5 208 ? 352.913 385.918 473.571 1.00 65.38  ? 208 CYS C N   1 
ATOM 6760 C CA  . CYS E 5 208 ? 352.966 384.854 472.586 1.00 65.38  ? 208 CYS C CA  1 
ATOM 6761 C C   . CYS E 5 208 ? 354.407 384.418 472.379 1.00 65.38  ? 208 CYS C C   1 
ATOM 6762 O O   . CYS E 5 208 ? 355.342 385.115 472.769 1.00 65.38  ? 208 CYS C O   1 
ATOM 6763 C CB  . CYS E 5 208 ? 352.368 385.332 471.267 1.00 65.38  ? 208 CYS C CB  1 
ATOM 6764 S SG  . CYS E 5 208 ? 350.648 385.845 471.405 1.00 65.38  ? 208 CYS C SG  1 
ATOM 6765 N N   . ASP E 5 209 ? 354.585 383.250 471.769 1.00 58.81  ? 209 ASP C N   1 
ATOM 6766 C CA  . ASP E 5 209 ? 355.902 382.669 471.554 1.00 58.81  ? 209 ASP C CA  1 
ATOM 6767 C C   . ASP E 5 209 ? 356.118 382.348 470.080 1.00 58.81  ? 209 ASP C C   1 
ATOM 6768 O O   . ASP E 5 209 ? 355.170 382.238 469.304 1.00 58.81  ? 209 ASP C O   1 
ATOM 6769 C CB  . ASP E 5 209 ? 356.090 381.394 472.383 1.00 58.81  ? 209 ASP C CB  1 
ATOM 6770 C CG  . ASP E 5 209 ? 356.051 381.643 473.885 1.00 58.81  ? 209 ASP C CG  1 
ATOM 6771 O OD1 . ASP E 5 209 ? 356.036 382.801 474.325 1.00 58.81  ? 209 ASP C OD1 1 
ATOM 6772 O OD2 . ASP E 5 209 ? 356.029 380.660 474.649 1.00 58.81  ? 209 ASP C OD2 1 
ATOM 6773 N N   . ILE E 5 210 ? 357.389 382.200 469.699 1.00 55.85  ? 210 ILE C N   1 
ATOM 6774 C CA  . ILE E 5 210 ? 357.796 381.827 468.346 1.00 55.85  ? 210 ILE C CA  1 
ATOM 6775 C C   . ILE E 5 210 ? 358.747 380.640 468.447 1.00 55.85  ? 210 ILE C C   1 
ATOM 6776 O O   . ILE E 5 210 ? 359.626 380.623 469.310 1.00 55.85  ? 210 ILE C O   1 
ATOM 6777 C CB  . ILE E 5 210 ? 358.490 382.991 467.609 1.00 55.85  ? 210 ILE C CB  1 
ATOM 6778 C CG1 . ILE E 5 210 ? 357.628 384.244 467.584 1.00 55.85  ? 210 ILE C CG1 1 
ATOM 6779 C CG2 . ILE E 5 210 ? 358.818 382.617 466.184 1.00 55.85  ? 210 ILE C CG2 1 
ATOM 6780 C CD1 . ILE E 5 210 ? 358.267 385.394 466.843 1.00 55.85  ? 210 ILE C CD1 1 
ATOM 6781 N N   . LEU E 5 211 ? 358.563 379.644 467.587 1.00 54.74  ? 211 LEU C N   1 
ATOM 6782 C CA  . LEU E 5 211 ? 359.503 378.543 467.446 1.00 54.74  ? 211 LEU C CA  1 
ATOM 6783 C C   . LEU E 5 211 ? 360.284 378.690 466.149 1.00 54.74  ? 211 LEU C C   1 
ATOM 6784 O O   . LEU E 5 211 ? 359.768 379.179 465.148 1.00 54.74  ? 211 LEU C O   1 
ATOM 6785 C CB  . LEU E 5 211 ? 358.779 377.199 467.447 1.00 54.74  ? 211 LEU C CB  1 
ATOM 6786 C CG  . LEU E 5 211 ? 358.103 376.672 468.702 1.00 54.74  ? 211 LEU C CG  1 
ATOM 6787 C CD1 . LEU E 5 211 ? 357.494 375.347 468.379 1.00 54.74  ? 211 LEU C CD1 1 
ATOM 6788 C CD2 . LEU E 5 211 ? 359.096 376.513 469.804 1.00 54.74  ? 211 LEU C CD2 1 
ATOM 6789 N N   . CYS E 5 212 ? 361.530 378.228 466.161 1.00 56.35  ? 212 CYS C N   1 
ATOM 6790 C CA  . CYS E 5 212 ? 362.398 378.379 465.004 1.00 56.35  ? 212 CYS C CA  1 
ATOM 6791 C C   . CYS E 5 212 ? 362.963 377.033 464.588 1.00 56.35  ? 212 CYS C C   1 
ATOM 6792 O O   . CYS E 5 212 ? 363.578 376.339 465.397 1.00 56.35  ? 212 CYS C O   1 
ATOM 6793 C CB  . CYS E 5 212 ? 363.543 379.344 465.297 1.00 56.35  ? 212 CYS C CB  1 
ATOM 6794 S SG  . CYS E 5 212 ? 364.884 379.268 464.109 1.00 56.35  ? 212 CYS C SG  1 
ATOM 6795 N N   . PHE E 5 213 ? 362.771 376.676 463.325 1.00 55.73  ? 213 PHE C N   1 
ATOM 6796 C CA  . PHE E 5 213 ? 363.244 375.415 462.784 1.00 55.73  ? 213 PHE C CA  1 
ATOM 6797 C C   . PHE E 5 213 ? 364.380 375.667 461.812 1.00 55.73  ? 213 PHE C C   1 
ATOM 6798 O O   . PHE E 5 213 ? 364.426 376.697 461.145 1.00 55.73  ? 213 PHE C O   1 
ATOM 6799 C CB  . PHE E 5 213 ? 362.134 374.661 462.061 1.00 55.73  ? 213 PHE C CB  1 
ATOM 6800 C CG  . PHE E 5 213 ? 360.933 374.419 462.897 1.00 55.73  ? 213 PHE C CG  1 
ATOM 6801 C CD1 . PHE E 5 213 ? 360.905 373.381 463.791 1.00 55.73  ? 213 PHE C CD1 1 
ATOM 6802 C CD2 . PHE E 5 213 ? 359.829 375.230 462.788 1.00 55.73  ? 213 PHE C CD2 1 
ATOM 6803 C CE1 . PHE E 5 213 ? 359.809 373.163 464.561 1.00 55.73  ? 213 PHE C CE1 1 
ATOM 6804 C CE2 . PHE E 5 213 ? 358.724 375.011 463.563 1.00 55.73  ? 213 PHE C CE2 1 
ATOM 6805 C CZ  . PHE E 5 213 ? 358.717 373.981 464.449 1.00 55.73  ? 213 PHE C CZ  1 
ATOM 6806 N N   . VAL E 5 214 ? 365.291 374.704 461.718 1.00 58.09  ? 214 VAL C N   1 
ATOM 6807 C CA  . VAL E 5 214 ? 366.448 374.820 460.844 1.00 58.09  ? 214 VAL C CA  1 
ATOM 6808 C C   . VAL E 5 214 ? 366.527 373.548 460.021 1.00 58.09  ? 214 VAL C C   1 
ATOM 6809 O O   . VAL E 5 214 ? 366.022 372.501 460.424 1.00 58.09  ? 214 VAL C O   1 
ATOM 6810 C CB  . VAL E 5 214 ? 367.739 375.070 461.657 1.00 58.09  ? 214 VAL C CB  1 
ATOM 6811 C CG1 . VAL E 5 214 ? 368.197 373.827 462.377 1.00 58.09  ? 214 VAL C CG1 1 
ATOM 6812 C CG2 . VAL E 5 214 ? 368.830 375.645 460.816 1.00 58.09  ? 214 VAL C CG2 1 
ATOM 6813 N N   . SER E 5 215 ? 367.124 373.641 458.847 1.00 62.99  ? 215 SER C N   1 
ATOM 6814 C CA  . SER E 5 215 ? 367.210 372.488 457.972 1.00 62.99  ? 215 SER C CA  1 
ATOM 6815 C C   . SER E 5 215 ? 368.438 372.639 457.096 1.00 62.99  ? 215 SER C C   1 
ATOM 6816 O O   . SER E 5 215 ? 369.236 373.564 457.265 1.00 62.99  ? 215 SER C O   1 
ATOM 6817 C CB  . SER E 5 215 ? 365.945 372.348 457.132 1.00 62.99  ? 215 SER C CB  1 
ATOM 6818 O OG  . SER E 5 215 ? 366.179 371.506 456.024 1.00 62.99  ? 215 SER C OG  1 
ATOM 6819 N N   . ALA E 5 216 ? 368.592 371.725 456.161 1.00 65.02  ? 216 ALA C N   1 
ATOM 6820 C CA  . ALA E 5 216 ? 369.599 371.834 455.129 1.00 65.02  ? 216 ALA C CA  1 
ATOM 6821 C C   . ALA E 5 216 ? 368.884 372.119 453.826 1.00 65.02  ? 216 ALA C C   1 
ATOM 6822 O O   . ALA E 5 216 ? 367.849 371.517 453.536 1.00 65.02  ? 216 ALA C O   1 
ATOM 6823 C CB  . ALA E 5 216 ? 370.417 370.562 455.016 1.00 65.02  ? 216 ALA C CB  1 
ATOM 6824 N N   . CYS E 5 217 ? 369.432 373.029 453.036 1.00 72.19  ? 217 CYS C N   1 
ATOM 6825 C CA  . CYS E 5 217 ? 368.780 373.434 451.803 1.00 72.19  ? 217 CYS C CA  1 
ATOM 6826 C C   . CYS E 5 217 ? 369.191 372.567 450.622 1.00 72.19  ? 217 CYS C C   1 
ATOM 6827 O O   . CYS E 5 217 ? 369.239 373.063 449.496 1.00 72.19  ? 217 CYS C O   1 
ATOM 6828 C CB  . CYS E 5 217 ? 369.061 374.905 451.521 1.00 72.19  ? 217 CYS C CB  1 
ATOM 6829 S SG  . CYS E 5 217 ? 367.769 375.740 450.592 1.00 72.19  ? 217 CYS C SG  1 
ATOM 6830 N N   . ASN E 5 218 ? 369.526 371.301 450.881 1.00 82.66  ? 218 ASN C N   1 
ATOM 6831 C CA  . ASN E 5 218 ? 369.572 370.130 450.002 1.00 82.66  ? 218 ASN C CA  1 
ATOM 6832 C C   . ASN E 5 218 ? 370.819 370.074 449.112 1.00 82.66  ? 218 ASN C C   1 
ATOM 6833 O O   . ASN E 5 218 ? 371.124 368.997 448.585 1.00 82.66  ? 218 ASN C O   1 
ATOM 6834 C CB  . ASN E 5 218 ? 368.275 370.057 449.158 1.00 82.66  ? 218 ASN C CB  1 
ATOM 6835 C CG  . ASN E 5 218 ? 368.193 368.852 448.243 1.00 82.66  ? 218 ASN C CG  1 
ATOM 6836 O OD1 . ASN E 5 218 ? 367.913 367.738 448.684 1.00 82.66  ? 218 ASN C OD1 1 
ATOM 6837 N ND2 . ASN E 5 218 ? 368.433 369.074 446.956 1.00 82.66  ? 218 ASN C ND2 1 
ATOM 6838 N N   . ASP E 5 219 ? 371.636 371.113 449.034 1.00 81.69  ? 219 ASP C N   1 
ATOM 6839 C CA  . ASP E 5 219 ? 372.635 371.109 447.973 1.00 81.69  ? 219 ASP C CA  1 
ATOM 6840 C C   . ASP E 5 219 ? 374.073 371.225 448.465 1.00 81.69  ? 219 ASP C C   1 
ATOM 6841 O O   . ASP E 5 219 ? 374.876 371.922 447.842 1.00 81.69  ? 219 ASP C O   1 
ATOM 6842 C CB  . ASP E 5 219 ? 372.361 372.217 446.951 1.00 81.69  ? 219 ASP C CB  1 
ATOM 6843 C CG  . ASP E 5 219 ? 372.195 373.600 447.583 1.00 81.69  ? 219 ASP C CG  1 
ATOM 6844 O OD1 . ASP E 5 219 ? 373.209 374.241 447.922 1.00 81.69  ? 219 ASP C OD1 1 
ATOM 6845 O OD2 . ASP E 5 219 ? 371.054 374.089 447.657 1.00 81.69  ? 219 ASP C OD2 1 
ATOM 6846 N N   . PHE E 5 220 ? 374.480 370.526 449.529 1.00 74.52  ? 220 PHE C N   1 
ATOM 6847 C CA  . PHE E 5 220 ? 375.854 370.734 449.963 1.00 74.52  ? 220 PHE C CA  1 
ATOM 6848 C C   . PHE E 5 220 ? 376.572 369.524 450.526 1.00 74.52  ? 220 PHE C C   1 
ATOM 6849 O O   . PHE E 5 220 ? 375.968 368.489 450.811 1.00 74.52  ? 220 PHE C O   1 
ATOM 6850 C CB  . PHE E 5 220 ? 375.947 371.861 450.950 1.00 74.52  ? 220 PHE C CB  1 
ATOM 6851 C CG  . PHE E 5 220 ? 375.479 371.572 452.336 1.00 74.52  ? 220 PHE C CG  1 
ATOM 6852 C CD1 . PHE E 5 220 ? 374.147 371.656 452.664 1.00 74.52  ? 220 PHE C CD1 1 
ATOM 6853 C CD2 . PHE E 5 220 ? 376.401 371.410 453.353 1.00 74.52  ? 220 PHE C CD2 1 
ATOM 6854 C CE1 . PHE E 5 220 ? 373.747 371.478 453.955 1.00 74.52  ? 220 PHE C CE1 1 
ATOM 6855 C CE2 . PHE E 5 220 ? 375.999 371.236 454.636 1.00 74.52  ? 220 PHE C CE2 1 
ATOM 6856 C CZ  . PHE E 5 220 ? 374.676 371.270 454.938 1.00 74.52  ? 220 PHE C CZ  1 
ATOM 6857 N N   . SER E 5 221 ? 377.879 369.716 450.696 1.00 71.16  ? 221 SER C N   1 
ATOM 6858 C CA  . SER E 5 221 ? 378.895 368.680 450.699 1.00 71.16  ? 221 SER C CA  1 
ATOM 6859 C C   . SER E 5 221 ? 379.834 368.828 451.883 1.00 71.16  ? 221 SER C C   1 
ATOM 6860 O O   . SER E 5 221 ? 380.095 369.928 452.364 1.00 71.16  ? 221 SER C O   1 
ATOM 6861 C CB  . SER E 5 221 ? 379.724 368.753 449.423 1.00 71.16  ? 221 SER C CB  1 
ATOM 6862 O OG  . SER E 5 221 ? 380.618 369.844 449.520 1.00 71.16  ? 221 SER C OG  1 
ATOM 6863 N N   . VAL E 5 222 ? 380.389 367.693 452.300 1.00 63.72  ? 222 VAL C N   1 
ATOM 6864 C CA  . VAL E 5 222 ? 381.261 367.588 453.455 1.00 63.72  ? 222 VAL C CA  1 
ATOM 6865 C C   . VAL E 5 222 ? 382.511 366.821 453.050 1.00 63.72  ? 222 VAL C C   1 
ATOM 6866 O O   . VAL E 5 222 ? 382.475 365.956 452.176 1.00 63.72  ? 222 VAL C O   1 
ATOM 6867 C CB  . VAL E 5 222 ? 380.552 366.892 454.628 1.00 63.72  ? 222 VAL C CB  1 
ATOM 6868 C CG1 . VAL E 5 222 ? 379.471 367.764 455.185 1.00 63.72  ? 222 VAL C CG1 1 
ATOM 6869 C CG2 . VAL E 5 222 ? 379.920 365.623 454.151 1.00 63.72  ? 222 VAL C CG2 1 
ATOM 6870 N N   . ARG E 5 223 ? 383.636 367.163 453.676 1.00 64.67  ? 223 ARG C N   1 
ATOM 6871 C CA  . ARG E 5 223 ? 384.904 366.516 453.354 1.00 64.67  ? 223 ARG C CA  1 
ATOM 6872 C C   . ARG E 5 223 ? 385.701 366.288 454.629 1.00 64.67  ? 223 ARG C C   1 
ATOM 6873 O O   . ARG E 5 223 ? 385.546 367.018 455.607 1.00 64.67  ? 223 ARG C O   1 
ATOM 6874 C CB  . ARG E 5 223 ? 385.725 367.346 452.360 1.00 64.67  ? 223 ARG C CB  1 
ATOM 6875 C CG  . ARG E 5 223 ? 385.172 367.370 450.945 1.00 64.67  ? 223 ARG C CG  1 
ATOM 6876 C CD  . ARG E 5 223 ? 385.832 368.404 450.086 1.00 64.67  ? 223 ARG C CD  1 
ATOM 6877 N NE  . ARG E 5 223 ? 387.198 368.040 449.744 1.00 64.67  ? 223 ARG C NE  1 
ATOM 6878 C CZ  . ARG E 5 223 ? 387.878 368.591 448.748 1.00 64.67  ? 223 ARG C CZ  1 
ATOM 6879 N NH1 . ARG E 5 223 ? 387.313 369.528 448.001 1.00 64.67  ? 223 ARG C NH1 1 
ATOM 6880 N NH2 . ARG E 5 223 ? 389.117 368.206 448.493 1.00 64.67  ? 223 ARG C NH2 1 
ATOM 6881 N N   . MET E 5 224 ? 386.564 365.264 454.592 1.00 60.78  ? 224 MET C N   1 
ATOM 6882 C CA  . MET E 5 224 ? 387.565 364.958 455.625 1.00 60.78  ? 224 MET C CA  1 
ATOM 6883 C C   . MET E 5 224 ? 386.923 364.669 456.986 1.00 60.78  ? 224 MET C C   1 
ATOM 6884 O O   . MET E 5 224 ? 386.890 365.513 457.875 1.00 60.78  ? 224 MET C O   1 
ATOM 6885 C CB  . MET E 5 224 ? 388.609 366.072 455.740 1.00 60.78  ? 224 MET C CB  1 
ATOM 6886 C CG  . MET E 5 224 ? 389.845 365.693 456.537 1.00 60.78  ? 224 MET C CG  1 
ATOM 6887 S SD  . MET E 5 224 ? 390.811 364.414 455.747 1.00 60.78  ? 224 MET C SD  1 
ATOM 6888 C CE  . MET E 5 224 ? 391.371 365.310 454.313 1.00 60.78  ? 224 MET C CE  1 
ATOM 6889 N N   . LEU E 5 225 ? 386.337 363.476 457.085 1.00 56.59  ? 225 LEU C N   1 
ATOM 6890 C CA  . LEU E 5 225 ? 385.706 363.031 458.324 1.00 56.59  ? 225 LEU C CA  1 
ATOM 6891 C C   . LEU E 5 225 ? 386.693 362.955 459.478 1.00 56.59  ? 225 LEU C C   1 
ATOM 6892 O O   . LEU E 5 225 ? 387.786 362.407 459.349 1.00 56.59  ? 225 LEU C O   1 
ATOM 6893 C CB  . LEU E 5 225 ? 385.054 361.665 458.116 1.00 56.59  ? 225 LEU C CB  1 
ATOM 6894 C CG  . LEU E 5 225 ? 384.164 361.025 459.185 1.00 56.59  ? 225 LEU C CG  1 
ATOM 6895 C CD1 . LEU E 5 225 ? 383.063 360.304 458.493 1.00 56.59  ? 225 LEU C CD1 1 
ATOM 6896 C CD2 . LEU E 5 225 ? 384.904 360.025 460.025 1.00 56.59  ? 225 LEU C CD2 1 
ATOM 6897 N N   . LYS E 5 226 ? 386.283 363.501 460.618 1.00 57.97  ? 226 LYS C N   1 
ATOM 6898 C CA  . LYS E 5 226 ? 387.021 363.431 461.868 1.00 57.97  ? 226 LYS C CA  1 
ATOM 6899 C C   . LYS E 5 226 ? 386.043 363.024 462.953 1.00 57.97  ? 226 LYS C C   1 
ATOM 6900 O O   . LYS E 5 226 ? 384.900 362.672 462.671 1.00 57.97  ? 226 LYS C O   1 
ATOM 6901 C CB  . LYS E 5 226 ? 387.687 364.765 462.200 1.00 57.97  ? 226 LYS C CB  1 
ATOM 6902 C CG  . LYS E 5 226 ? 386.715 365.903 462.413 1.00 57.97  ? 226 LYS C CG  1 
ATOM 6903 C CD  . LYS E 5 226 ? 387.361 367.041 463.162 1.00 57.97  ? 226 LYS C CD  1 
ATOM 6904 C CE  . LYS E 5 226 ? 386.395 368.182 463.349 1.00 57.97  ? 226 LYS C CE  1 
ATOM 6905 N NZ  . LYS E 5 226 ? 385.387 367.893 464.386 1.00 57.97  ? 226 LYS C NZ  1 
ATOM 6906 N N   . ASP E 5 227 ? 386.475 363.067 464.202 1.00 63.16  ? 227 ASP C N   1 
ATOM 6907 C CA  . ASP E 5 227 ? 385.566 362.708 465.276 1.00 63.16  ? 227 ASP C CA  1 
ATOM 6908 C C   . ASP E 5 227 ? 385.057 363.952 465.990 1.00 63.16  ? 227 ASP C C   1 
ATOM 6909 O O   . ASP E 5 227 ? 385.727 364.981 466.053 1.00 63.16  ? 227 ASP C O   1 
ATOM 6910 C CB  . ASP E 5 227 ? 386.239 361.771 466.269 1.00 63.16  ? 227 ASP C CB  1 
ATOM 6911 C CG  . ASP E 5 227 ? 387.509 362.335 466.818 1.00 63.16  ? 227 ASP C CG  1 
ATOM 6912 O OD1 . ASP E 5 227 ? 388.069 363.254 466.193 1.00 63.16  ? 227 ASP C OD1 1 
ATOM 6913 O OD2 . ASP E 5 227 ? 387.959 361.853 467.874 1.00 63.16  ? 227 ASP C OD2 1 
ATOM 6914 N N   . THR E 5 228 ? 383.908 363.841 466.520 1.00 63.20  ? 228 THR C N   1 
ATOM 6915 C CA  . THR E 5 228 ? 383.110 364.888 467.126 1.00 63.20  ? 228 THR C CA  1 
ATOM 6916 C C   . THR E 5 228 ? 383.770 365.414 468.394 1.00 63.20  ? 228 THR C C   1 
ATOM 6917 O O   . THR E 5 228 ? 384.464 364.674 469.095 1.00 63.20  ? 228 THR C O   1 
ATOM 6918 C CB  . THR E 5 228 ? 381.714 364.364 467.443 1.00 63.20  ? 228 THR C CB  1 
ATOM 6919 O OG1 . THR E 5 228 ? 380.993 365.332 468.204 1.00 63.20  ? 228 THR C OG1 1 
ATOM 6920 C CG2 . THR E 5 228 ? 381.779 363.073 468.216 1.00 63.20  ? 228 THR C CG2 1 
ATOM 6921 N N   . PRO E 5 229 ? 383.625 366.704 468.691 1.00 64.57  ? 229 PRO C N   1 
ATOM 6922 C CA  . PRO E 5 229 ? 384.116 367.243 469.965 1.00 64.57  ? 229 PRO C CA  1 
ATOM 6923 C C   . PRO E 5 229 ? 383.170 367.055 471.139 1.00 64.57  ? 229 PRO C C   1 
ATOM 6924 O O   . PRO E 5 229 ? 383.500 367.488 472.245 1.00 64.57  ? 229 PRO C O   1 
ATOM 6925 C CB  . PRO E 5 229 ? 384.272 368.730 469.644 1.00 64.57  ? 229 PRO C CB  1 
ATOM 6926 C CG  . PRO E 5 229 ? 383.230 368.982 468.648 1.00 64.57  ? 229 PRO C CG  1 
ATOM 6927 C CD  . PRO E 5 229 ? 383.189 367.777 467.785 1.00 64.57  ? 229 PRO C CD  1 
ATOM 6928 N N   . PHE E 5 230 ? 382.019 366.433 470.929 1.00 65.91  ? 230 PHE C N   1 
ATOM 6929 C CA  . PHE E 5 230 ? 381.069 366.156 471.999 1.00 65.91  ? 230 PHE C CA  1 
ATOM 6930 C C   . PHE E 5 230 ? 381.326 364.798 472.632 1.00 65.91  ? 230 PHE C C   1 
ATOM 6931 O O   . PHE E 5 230 ? 380.521 363.883 472.517 1.00 65.91  ? 230 PHE C O   1 
ATOM 6932 C CB  . PHE E 5 230 ? 379.652 366.236 471.457 1.00 65.91  ? 230 PHE C CB  1 
ATOM 6933 C CG  . PHE E 5 230 ? 379.349 367.516 470.760 1.00 65.91  ? 230 PHE C CG  1 
ATOM 6934 C CD1 . PHE E 5 230 ? 379.668 368.725 471.340 1.00 65.91  ? 230 PHE C CD1 1 
ATOM 6935 C CD2 . PHE E 5 230 ? 378.746 367.511 469.521 1.00 65.91  ? 230 PHE C CD2 1 
ATOM 6936 C CE1 . PHE E 5 230 ? 379.390 369.906 470.695 1.00 65.91  ? 230 PHE C CE1 1 
ATOM 6937 C CE2 . PHE E 5 230 ? 378.463 368.684 468.877 1.00 65.91  ? 230 PHE C CE2 1 
ATOM 6938 C CZ  . PHE E 5 230 ? 378.789 369.883 469.461 1.00 65.91  ? 230 PHE C CZ  1 
ATOM 6939 N N   . ILE E 5 231 ? 382.474 364.656 473.287 1.00 76.47  ? 231 ILE C N   1 
ATOM 6940 C CA  . ILE E 5 231 ? 382.821 363.464 474.052 1.00 76.47  ? 231 ILE C CA  1 
ATOM 6941 C C   . ILE E 5 231 ? 383.855 363.880 475.094 1.00 76.47  ? 231 ILE C C   1 
ATOM 6942 O O   . ILE E 5 231 ? 384.445 364.959 475.009 1.00 76.47  ? 231 ILE C O   1 
ATOM 6943 C CB  . ILE E 5 231 ? 383.337 362.325 473.144 1.00 76.47  ? 231 ILE C CB  1 
ATOM 6944 C CG1 . ILE E 5 231 ? 382.844 360.981 473.659 1.00 76.47  ? 231 ILE C CG1 1 
ATOM 6945 C CG2 . ILE E 5 231 ? 384.856 362.357 472.982 1.00 76.47  ? 231 ILE C CG2 1 
ATOM 6946 C CD1 . ILE E 5 231 ? 381.378 360.782 473.425 1.00 76.47  ? 231 ILE C CD1 1 
ATOM 6947 N N   . ARG E 5 232 ? 384.046 363.036 476.106 1.00 84.39  ? 232 ARG C N   1 
ATOM 6948 C CA  . ARG E 5 232 ? 384.944 363.334 477.221 1.00 84.39  ? 232 ARG C CA  1 
ATOM 6949 C C   . ARG E 5 232 ? 386.401 363.569 476.813 1.00 84.39  ? 232 ARG C C   1 
ATOM 6950 O O   . ARG E 5 232 ? 386.840 363.123 475.757 1.00 84.39  ? 232 ARG C O   1 
ATOM 6951 C CB  . ARG E 5 232 ? 384.873 362.204 478.252 1.00 84.39  ? 232 ARG C CB  1 
ATOM 6952 C CG  . ARG E 5 232 ? 385.068 360.796 477.691 1.00 84.39  ? 232 ARG C CG  1 
ATOM 6953 C CD  . ARG E 5 232 ? 386.503 360.310 477.841 1.00 84.39  ? 232 ARG C CD  1 
ATOM 6954 N NE  . ARG E 5 232 ? 386.650 358.886 477.582 1.00 84.39  ? 232 ARG C NE  1 
ATOM 6955 C CZ  . ARG E 5 232 ? 387.822 358.287 477.415 1.00 84.39  ? 232 ARG C CZ  1 
ATOM 6956 N NH1 . ARG E 5 232 ? 388.940 358.996 477.463 1.00 84.39  ? 232 ARG C NH1 1 
ATOM 6957 N NH2 . ARG E 5 232 ? 387.874 356.983 477.195 1.00 84.39  ? 232 ARG C NH2 1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   LYS 3   3   3   LYS LYS H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  GLN 13  13  13  GLN GLN H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  SER 19  19  19  SER SER H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  ALA 23  23  23  ALA ALA H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  THR 28  28  28  THR THR H . n 
A 1 29  PHE 29  29  29  PHE PHE H . n 
A 1 30  THR 30  30  30  THR THR H . n 
A 1 31  ASP 31  31  31  ASP ASP H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  TYR 33  33  33  TYR TYR H . n 
A 1 34  MET 34  34  34  MET MET H . n 
A 1 35  ASN 35  35  35  ASN ASN H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  PRO 40  40  40  PRO PRO H . n 
A 1 41  SER 41  41  41  SER SER H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  ALA 44  44  44  ALA ALA H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  TRP 47  47  47  TRP TRP H . n 
A 1 48  LEU 48  48  48  LEU LEU H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  PHE 50  50  50  PHE PHE H . n 
A 1 51  LEU 51  51  51  LEU LEU H . n 
A 1 52  ARG 52  52  52  ARG ARG H . n 
A 1 53  ASN 53  53  53  ASN ASN H . n 
A 1 54  LYS 54  54  54  LYS LYS H . n 
A 1 55  ALA 55  55  55  ALA ALA H . n 
A 1 56  ASN 56  56  56  ASN ASN H . n 
A 1 57  GLY 57  57  57  GLY GLY H . n 
A 1 58  TYR 58  58  58  TYR TYR H . n 
A 1 59  THR 59  59  59  THR THR H . n 
A 1 60  THR 60  60  60  THR THR H . n 
A 1 61  GLU 61  61  61  GLU GLU H . n 
A 1 62  TYR 62  62  62  TYR TYR H . n 
A 1 63  SER 63  63  63  SER SER H . n 
A 1 64  ALA 64  64  64  ALA ALA H . n 
A 1 65  SER 65  65  65  SER SER H . n 
A 1 66  VAL 66  66  66  VAL VAL H . n 
A 1 67  LYS 67  67  67  LYS LYS H . n 
A 1 68  GLY 68  68  68  GLY GLY H . n 
A 1 69  ARG 69  69  69  ARG ARG H . n 
A 1 70  PHE 70  70  70  PHE PHE H . n 
A 1 71  THR 71  71  71  THR THR H . n 
A 1 72  ILE 72  72  72  ILE ILE H . n 
A 1 73  SER 73  73  73  SER SER H . n 
A 1 74  ARG 74  74  74  ARG ARG H . n 
A 1 75  ASP 75  75  75  ASP ASP H . n 
A 1 76  ASN 76  76  76  ASN ASN H . n 
A 1 77  SER 77  77  77  SER SER H . n 
A 1 78  GLN 78  78  78  GLN GLN H . n 
A 1 79  SER 79  79  79  SER SER H . n 
A 1 80  ILE 80  80  80  ILE ILE H . n 
A 1 81  LEU 81  81  81  LEU LEU H . n 
A 1 82  TYR 82  82  82  TYR TYR H . n 
A 1 83  LEU 83  83  83  LEU LEU H . n 
A 1 84  GLN 84  84  84  GLN GLN H . n 
A 1 85  MET 85  85  85  MET MET H . n 
A 1 86  ASN 86  86  86  ASN ASN H . n 
A 1 87  ALA 87  87  87  ALA ALA H . n 
A 1 88  LEU 88  88  88  LEU LEU H . n 
A 1 89  ARG 89  89  89  ARG ARG H . n 
A 1 90  ALA 90  90  90  ALA ALA H . n 
A 1 91  GLU 91  91  91  GLU GLU H . n 
A 1 92  ASP 92  92  92  ASP ASP H . n 
A 1 93  SER 93  93  93  SER SER H . n 
A 1 94  ALA 94  94  94  ALA ALA H . n 
A 1 95  THR 95  95  95  THR THR H . n 
A 1 96  TYR 96  96  96  TYR TYR H . n 
A 1 97  TYR 97  97  97  TYR TYR H . n 
A 1 98  CYS 98  98  98  CYS CYS H . n 
A 1 99  ALA 99  99  99  ALA ALA H . n 
A 1 100 ARG 100 100 100 ARG ARG H . n 
A 1 101 SER 101 101 101 SER SER H . n 
A 1 102 ARG 102 102 102 ARG ARG H . n 
A 1 103 TYR 103 103 103 TYR TYR H . n 
A 1 104 TYR 104 104 104 TYR TYR H . n 
A 1 105 GLY 105 105 105 GLY GLY H . n 
A 1 106 GLY 106 106 106 GLY GLY H . n 
A 1 107 THR 107 107 107 THR THR H . n 
A 1 108 TYR 108 108 108 TYR TYR H . n 
A 1 109 ARG 109 109 109 ARG ARG H . n 
A 1 110 TYR 110 110 110 TYR TYR H . n 
A 1 111 ALA 111 111 111 ALA ALA H . n 
A 1 112 LEU 112 112 112 LEU LEU H . n 
A 1 113 ASP 113 113 113 ASP ASP H . n 
A 1 114 TYR 114 114 114 TYR TYR H . n 
A 1 115 TRP 115 115 115 TRP TRP H . n 
A 1 116 GLY 116 116 116 GLY GLY H . n 
A 1 117 GLN 117 117 117 GLN GLN H . n 
A 1 118 GLY 118 118 118 GLY GLY H . n 
A 1 119 THR 119 119 119 THR THR H . n 
A 1 120 SER 120 120 120 SER SER H . n 
A 1 121 VAL 121 121 121 VAL VAL H . n 
A 1 122 THR 122 122 122 THR THR H . n 
A 1 123 VAL 123 123 123 VAL VAL H . n 
A 1 124 SER 124 124 124 SER SER H . n 
B 2 1   GLU 1   1   ?   ?   ?   L . n 
B 2 2   ASN 2   2   2   ASN ASN L . n 
B 2 3   VAL 3   3   3   VAL VAL L . n 
B 2 4   LEU 4   4   4   LEU LEU L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   PRO 9   9   9   PRO PRO L . n 
B 2 10  ILE 10  10  10  ILE ILE L . n 
B 2 11  MET 11  11  11  MET MET L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  PRO 15  15  15  PRO PRO L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  GLU 17  17  17  GLU GLU L . n 
B 2 18  LYS 18  18  18  LYS LYS L . n 
B 2 19  VAL 19  19  19  VAL VAL L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  MET 21  21  21  MET MET L . n 
B 2 22  THR 22  22  22  THR THR L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  SER 27  27  27  SER SER L . n 
B 2 28  SER 28  28  28  SER SER L . n 
B 2 29  VAL 29  29  29  VAL VAL L . n 
B 2 30  SER 30  30  30  SER SER L . n 
B 2 31  SER 31  31  31  SER SER L . n 
B 2 32  SER 32  32  32  SER SER L . n 
B 2 33  TYR 33  33  33  TYR TYR L . n 
B 2 34  LEU 34  34  34  LEU LEU L . n 
B 2 35  HIS 35  35  35  HIS HIS L . n 
B 2 36  TRP 36  36  36  TRP TRP L . n 
B 2 37  TYR 37  37  37  TYR TYR L . n 
B 2 38  GLN 38  38  38  GLN GLN L . n 
B 2 39  GLN 39  39  39  GLN GLN L . n 
B 2 40  LYS 40  40  40  LYS LYS L . n 
B 2 41  SER 41  41  41  SER SER L . n 
B 2 42  GLY 42  42  42  GLY GLY L . n 
B 2 43  ALA 43  43  43  ALA ALA L . n 
B 2 44  SER 44  44  44  SER SER L . n 
B 2 45  PRO 45  45  45  PRO PRO L . n 
B 2 46  LYS 46  46  46  LYS LYS L . n 
B 2 47  LEU 47  47  47  LEU LEU L . n 
B 2 48  TRP 48  48  48  TRP TRP L . n 
B 2 49  ILE 49  49  49  ILE ILE L . n 
B 2 50  TYR 50  50  50  TYR TYR L . n 
B 2 51  SER 51  51  51  SER SER L . n 
B 2 52  THR 52  52  52  THR THR L . n 
B 2 53  SER 53  53  53  SER SER L . n 
B 2 54  ASN 54  54  54  ASN ASN L . n 
B 2 55  LEU 55  55  55  LEU LEU L . n 
B 2 56  ALA 56  56  56  ALA ALA L . n 
B 2 57  SER 57  57  57  SER SER L . n 
B 2 58  GLY 58  58  58  GLY GLY L . n 
B 2 59  VAL 59  59  59  VAL VAL L . n 
B 2 60  PRO 60  60  60  PRO PRO L . n 
B 2 61  ALA 61  61  61  ALA ALA L . n 
B 2 62  ARG 62  62  62  ARG ARG L . n 
B 2 63  PHE 63  63  63  PHE PHE L . n 
B 2 64  SER 64  64  64  SER SER L . n 
B 2 65  GLY 65  65  65  GLY GLY L . n 
B 2 66  SER 66  66  66  SER SER L . n 
B 2 67  GLY 67  67  67  GLY GLY L . n 
B 2 68  SER 68  68  68  SER SER L . n 
B 2 69  GLY 69  69  69  GLY GLY L . n 
B 2 70  THR 70  70  70  THR THR L . n 
B 2 71  SER 71  71  71  SER SER L . n 
B 2 72  TYR 72  72  72  TYR TYR L . n 
B 2 73  SER 73  73  73  SER SER L . n 
B 2 74  LEU 74  74  74  LEU LEU L . n 
B 2 75  THR 75  75  75  THR THR L . n 
B 2 76  ILE 76  76  76  ILE ILE L . n 
B 2 77  SER 77  77  77  SER SER L . n 
B 2 78  SER 78  78  78  SER SER L . n 
B 2 79  VAL 79  79  79  VAL VAL L . n 
B 2 80  GLU 80  80  80  GLU GLU L . n 
B 2 81  ALA 81  81  81  ALA ALA L . n 
B 2 82  GLU 82  82  82  GLU GLU L . n 
B 2 83  ASP 83  83  83  ASP ASP L . n 
B 2 84  ALA 84  84  84  ALA ALA L . n 
B 2 85  ALA 85  85  85  ALA ALA L . n 
B 2 86  THR 86  86  86  THR THR L . n 
B 2 87  TYR 87  87  87  TYR TYR L . n 
B 2 88  TYR 88  88  88  TYR TYR L . n 
B 2 89  CYS 89  89  89  CYS CYS L . n 
B 2 90  GLN 90  90  90  GLN GLN L . n 
B 2 91  GLN 91  91  91  GLN GLN L . n 
B 2 92  PHE 92  92  92  PHE PHE L . n 
B 2 93  SER 93  93  93  SER SER L . n 
B 2 94  GLY 94  94  94  GLY GLY L . n 
B 2 95  TYR 95  95  95  TYR TYR L . n 
B 2 96  PRO 96  96  96  PRO PRO L . n 
B 2 97  LEU 97  97  97  LEU LEU L . n 
B 2 98  THR 98  98  98  THR THR L . n 
B 2 99  PHE 99  99  99  PHE PHE L . n 
B 2 100 GLY 100 100 100 GLY GLY L . n 
B 2 101 ALA 101 101 101 ALA ALA L . n 
B 2 102 GLY 102 102 102 GLY GLY L . n 
B 2 103 THR 103 103 103 THR THR L . n 
B 2 104 LYS 104 104 104 LYS LYS L . n 
B 2 105 LEU 105 105 105 LEU LEU L . n 
B 2 106 GLU 106 106 106 GLU GLU L . n 
B 2 107 LEU 107 107 107 LEU LEU L . n 
B 2 108 LYS 108 108 108 LYS LYS L . n 
C 3 1   GLY 1   1   ?   ?   ?   A . n 
C 3 2   PRO 2   2   ?   ?   ?   A . n 
C 3 3   VAL 3   3   ?   ?   ?   A . n 
C 3 4   GLU 4   4   ?   ?   ?   A . n 
C 3 5   GLU 5   5   ?   ?   ?   A . n 
C 3 6   SER 6   6   ?   ?   ?   A . n 
C 3 7   VAL 7   7   ?   ?   ?   A . n 
C 3 8   ASP 8   8   ?   ?   ?   A . n 
C 3 9   ARG 9   9   ?   ?   ?   A . n 
C 3 10  ALA 10  10  ?   ?   ?   A . n 
C 3 11  VAL 11  11  ?   ?   ?   A . n 
C 3 12  ALA 12  12  ?   ?   ?   A . n 
C 3 13  ARG 13  13  ?   ?   ?   A . n 
C 3 14  VAL 14  14  ?   ?   ?   A . n 
C 3 15  ALA 15  15  ?   ?   ?   A . n 
C 3 16  ASP 16  16  ?   ?   ?   A . n 
C 3 17  THR 17  17  ?   ?   ?   A . n 
C 3 18  ILE 18  18  ?   ?   ?   A . n 
C 3 19  SER 19  19  ?   ?   ?   A . n 
C 3 20  SER 20  20  ?   ?   ?   A . n 
C 3 21  ARG 21  21  ?   ?   ?   A . n 
C 3 22  PRO 22  22  ?   ?   ?   A . n 
C 3 23  THR 23  23  ?   ?   ?   A . n 
C 3 24  ASN 24  24  ?   ?   ?   A . n 
C 3 25  SER 25  25  ?   ?   ?   A . n 
C 3 26  GLU 26  26  ?   ?   ?   A . n 
C 3 27  SER 27  27  ?   ?   ?   A . n 
C 3 28  ILE 28  28  ?   ?   ?   A . n 
C 3 29  PRO 29  29  ?   ?   ?   A . n 
C 3 30  ALA 30  30  ?   ?   ?   A . n 
C 3 31  LEU 31  31  ?   ?   ?   A . n 
C 3 32  THR 32  32  ?   ?   ?   A . n 
C 3 33  ALA 33  33  ?   ?   ?   A . n 
C 3 34  ALA 34  34  ?   ?   ?   A . n 
C 3 35  GLU 35  35  ?   ?   ?   A . n 
C 3 36  THR 36  36  ?   ?   ?   A . n 
C 3 37  GLY 37  37  ?   ?   ?   A . n 
C 3 38  HIS 38  38  ?   ?   ?   A . n 
C 3 39  THR 39  39  ?   ?   ?   A . n 
C 3 40  SER 40  40  ?   ?   ?   A . n 
C 3 41  GLN 41  41  ?   ?   ?   A . n 
C 3 42  VAL 42  42  ?   ?   ?   A . n 
C 3 43  VAL 43  43  ?   ?   ?   A . n 
C 3 44  PRO 44  44  ?   ?   ?   A . n 
C 3 45  SER 45  45  ?   ?   ?   A . n 
C 3 46  ASP 46  46  ?   ?   ?   A . n 
C 3 47  THR 47  47  ?   ?   ?   A . n 
C 3 48  MET 48  48  ?   ?   ?   A . n 
C 3 49  GLN 49  49  ?   ?   ?   A . n 
C 3 50  THR 50  50  ?   ?   ?   A . n 
C 3 51  ARG 51  51  ?   ?   ?   A . n 
C 3 52  HIS 52  52  ?   ?   ?   A . n 
C 3 53  VAL 53  53  ?   ?   ?   A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ASN 55  55  ?   ?   ?   A . n 
C 3 56  TYR 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  SER 58  58  58  SER SER A . n 
C 3 59  ARG 59  59  59  ARG ARG A . n 
C 3 60  SER 60  60  60  SER SER A . n 
C 3 61  GLU 61  61  61  GLU GLU A . n 
C 3 62  SER 62  62  62  SER SER A . n 
C 3 63  SER 63  63  63  SER SER A . n 
C 3 64  ILE 64  64  64  ILE ILE A . n 
C 3 65  GLU 65  65  65  GLU GLU A . n 
C 3 66  ASN 66  66  66  ASN ASN A . n 
C 3 67  PHE 67  67  67  PHE PHE A . n 
C 3 68  LEU 68  68  68  LEU LEU A . n 
C 3 69  CYS 69  69  69  CYS CYS A . n 
C 3 70  ARG 70  70  70  ARG ARG A . n 
C 3 71  SER 71  71  71  SER SER A . n 
C 3 72  ALA 72  72  72  ALA ALA A . n 
C 3 73  CYS 73  73  73  CYS CYS A . n 
C 3 74  VAL 74  74  74  VAL VAL A . n 
C 3 75  TYR 75  75  75  TYR TYR A . n 
C 3 76  TYR 76  76  76  TYR TYR A . n 
C 3 77  ALA 77  77  77  ALA ALA A . n 
C 3 78  THR 78  78  78  THR THR A . n 
C 3 79  TYR 79  79  79  TYR TYR A . n 
C 3 80  THR 80  80  80  THR THR A . n 
C 3 81  ASN 81  81  81  ASN ASN A . n 
C 3 82  ASN 82  82  82  ASN ASN A . n 
C 3 83  SER 83  83  83  SER SER A . n 
C 3 84  LYS 84  84  84  LYS LYS A . n 
C 3 85  LYS 85  85  85  LYS LYS A . n 
C 3 86  GLY 86  86  86  GLY GLY A . n 
C 3 87  PHE 87  87  87  PHE PHE A . n 
C 3 88  ALA 88  88  88  ALA ALA A . n 
C 3 89  GLU 89  89  89  GLU GLU A . n 
C 3 90  TRP 90  90  90  TRP TRP A . n 
C 3 91  VAL 91  91  91  VAL VAL A . n 
C 3 92  ILE 92  92  92  ILE ILE A . n 
C 3 93  ASN 93  93  93  ASN ASN A . n 
C 3 94  THR 94  94  94  THR THR A . n 
C 3 95  ARG 95  95  95  ARG ARG A . n 
C 3 96  GLN 96  96  96  GLN GLN A . n 
C 3 97  VAL 97  97  97  VAL VAL A . n 
C 3 98  ALA 98  98  98  ALA ALA A . n 
C 3 99  GLN 99  99  99  GLN GLN A . n 
C 3 100 LEU 100 100 100 LEU LEU A . n 
C 3 101 ARG 101 101 101 ARG ARG A . n 
C 3 102 ARG 102 102 102 ARG ARG A . n 
C 3 103 LYS 103 103 103 LYS LYS A . n 
C 3 104 LEU 104 104 104 LEU LEU A . n 
C 3 105 GLU 105 105 105 GLU GLU A . n 
C 3 106 LEU 106 106 106 LEU LEU A . n 
C 3 107 PHE 107 107 107 PHE PHE A . n 
C 3 108 THR 108 108 108 THR THR A . n 
C 3 109 TYR 109 109 109 TYR TYR A . n 
C 3 110 LEU 110 110 110 LEU LEU A . n 
C 3 111 ARG 111 111 111 ARG ARG A . n 
C 3 112 PHE 112 112 112 PHE PHE A . n 
C 3 113 ASP 113 113 113 ASP ASP A . n 
C 3 114 LEU 114 114 114 LEU LEU A . n 
C 3 115 GLU 115 115 115 GLU GLU A . n 
C 3 116 LEU 116 116 116 LEU LEU A . n 
C 3 117 THR 117 117 117 THR THR A . n 
C 3 118 PHE 118 118 118 PHE PHE A . n 
C 3 119 VAL 119 119 119 VAL VAL A . n 
C 3 120 ILE 120 120 120 ILE ILE A . n 
C 3 121 THR 121 121 121 THR THR A . n 
C 3 122 SER 122 122 122 SER SER A . n 
C 3 123 ALA 123 123 123 ALA ALA A . n 
C 3 124 GLN 124 124 124 GLN GLN A . n 
C 3 125 GLN 125 125 125 GLN GLN A . n 
C 3 126 PRO 126 126 126 PRO PRO A . n 
C 3 127 SER 127 127 127 SER SER A . n 
C 3 128 THR 128 128 128 THR THR A . n 
C 3 129 ALA 129 129 129 ALA ALA A . n 
C 3 130 SER 130 130 130 SER SER A . n 
C 3 131 SER 131 131 131 SER SER A . n 
C 3 132 VAL 132 132 132 VAL VAL A . n 
C 3 133 ASP 133 133 133 ASP ASP A . n 
C 3 134 ALA 134 134 134 ALA ALA A . n 
C 3 135 PRO 135 135 135 PRO PRO A . n 
C 3 136 VAL 136 136 136 VAL VAL A . n 
C 3 137 GLN 137 137 137 GLN GLN A . n 
C 3 138 THR 138 138 138 THR THR A . n 
C 3 139 HIS 139 139 139 HIS HIS A . n 
C 3 140 GLN 140 140 140 GLN GLN A . n 
C 3 141 ILE 141 141 141 ILE ILE A . n 
C 3 142 MET 142 142 142 MET MET A . n 
C 3 143 TYR 143 143 143 TYR TYR A . n 
C 3 144 VAL 144 144 144 VAL VAL A . n 
C 3 145 PRO 145 145 145 PRO PRO A . n 
C 3 146 PRO 146 146 146 PRO PRO A . n 
C 3 147 GLY 147 147 147 GLY GLY A . n 
C 3 148 GLY 148 148 148 GLY GLY A . n 
C 3 149 PRO 149 149 149 PRO PRO A . n 
C 3 150 VAL 150 150 150 VAL VAL A . n 
C 3 151 PRO 151 151 151 PRO PRO A . n 
C 3 152 THR 152 152 152 THR THR A . n 
C 3 153 LYS 153 153 153 LYS LYS A . n 
C 3 154 VAL 154 154 154 VAL VAL A . n 
C 3 155 LYS 155 155 155 LYS LYS A . n 
C 3 156 ASP 156 156 156 ASP ASP A . n 
C 3 157 TYR 157 157 157 TYR TYR A . n 
C 3 158 ALA 158 158 158 ALA ALA A . n 
C 3 159 TRP 159 159 159 TRP TRP A . n 
C 3 160 GLN 160 160 160 GLN GLN A . n 
C 3 161 THR 161 161 161 THR THR A . n 
C 3 162 SER 162 162 162 SER SER A . n 
C 3 163 THR 163 163 163 THR THR A . n 
C 3 164 ASN 164 164 164 ASN ASN A . n 
C 3 165 PRO 165 165 165 PRO PRO A . n 
C 3 166 SER 166 166 166 SER SER A . n 
C 3 167 VAL 167 167 167 VAL VAL A . n 
C 3 168 PHE 168 168 168 PHE PHE A . n 
C 3 169 TRP 169 169 169 TRP TRP A . n 
C 3 170 THR 170 170 170 THR THR A . n 
C 3 171 GLU 171 171 171 GLU GLU A . n 
C 3 172 GLY 172 172 172 GLY GLY A . n 
C 3 173 ASN 173 173 173 ASN ASN A . n 
C 3 174 ALA 174 174 174 ALA ALA A . n 
C 3 175 PRO 175 175 175 PRO PRO A . n 
C 3 176 PRO 176 176 176 PRO PRO A . n 
C 3 177 ARG 177 177 177 ARG ARG A . n 
C 3 178 MET 178 178 178 MET MET A . n 
C 3 179 SER 179 179 179 SER SER A . n 
C 3 180 ILE 180 180 180 ILE ILE A . n 
C 3 181 PRO 181 181 181 PRO PRO A . n 
C 3 182 PHE 182 182 182 PHE PHE A . n 
C 3 183 ILE 183 183 183 ILE ILE A . n 
C 3 184 SER 184 184 184 SER SER A . n 
C 3 185 ILE 185 185 185 ILE ILE A . n 
C 3 186 GLY 186 186 186 GLY GLY A . n 
C 3 187 ASN 187 187 187 ASN ASN A . n 
C 3 188 ALA 188 188 188 ALA ALA A . n 
C 3 189 TYR 189 189 189 TYR TYR A . n 
C 3 190 SER 190 190 190 SER SER A . n 
C 3 191 CYS 191 191 191 CYS CYS A . n 
C 3 192 PHE 192 192 192 PHE PHE A . n 
C 3 193 TYR 193 193 193 TYR TYR A . n 
C 3 194 ASP 194 194 194 ASP ASP A . n 
C 3 195 GLY 195 195 195 GLY GLY A . n 
C 3 196 TRP 196 196 196 TRP TRP A . n 
C 3 197 THR 197 197 197 THR THR A . n 
C 3 198 GLN 198 198 ?   ?   ?   A . n 
C 3 199 PHE 199 199 ?   ?   ?   A . n 
C 3 200 SER 200 200 ?   ?   ?   A . n 
C 3 201 ARG 201 201 ?   ?   ?   A . n 
C 3 202 ASN 202 202 ?   ?   ?   A . n 
C 3 203 GLY 203 203 ?   ?   ?   A . n 
C 3 204 VAL 204 204 204 VAL VAL A . n 
C 3 205 TYR 205 205 205 TYR TYR A . n 
C 3 206 GLY 206 206 206 GLY GLY A . n 
C 3 207 ILE 207 207 207 ILE ILE A . n 
C 3 208 ASN 208 208 208 ASN ASN A . n 
C 3 209 THR 209 209 209 THR THR A . n 
C 3 210 LEU 210 210 210 LEU LEU A . n 
C 3 211 ASN 211 211 211 ASN ASN A . n 
C 3 212 ASN 212 212 212 ASN ASN A . n 
C 3 213 MET 213 213 213 MET MET A . n 
C 3 214 GLY 214 214 214 GLY GLY A . n 
C 3 215 THR 215 215 215 THR THR A . n 
C 3 216 LEU 216 216 216 LEU LEU A . n 
C 3 217 TYR 217 217 217 TYR TYR A . n 
C 3 218 MET 218 218 218 MET MET A . n 
C 3 219 ARG 219 219 219 ARG ARG A . n 
C 3 220 HIS 220 220 220 HIS HIS A . n 
C 3 221 VAL 221 221 221 VAL VAL A . n 
C 3 222 ASN 222 222 222 ASN ASN A . n 
C 3 223 GLU 223 223 223 GLU GLU A . n 
C 3 224 ALA 224 224 224 ALA ALA A . n 
C 3 225 GLY 225 225 225 GLY GLY A . n 
C 3 226 GLN 226 226 226 GLN GLN A . n 
C 3 227 GLY 227 227 227 GLY GLY A . n 
C 3 228 PRO 228 228 228 PRO PRO A . n 
C 3 229 ILE 229 229 229 ILE ILE A . n 
C 3 230 LYS 230 230 230 LYS LYS A . n 
C 3 231 SER 231 231 231 SER SER A . n 
C 3 232 THR 232 232 232 THR THR A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 ARG 234 234 234 ARG ARG A . n 
C 3 235 ILE 235 235 235 ILE ILE A . n 
C 3 236 TYR 236 236 236 TYR TYR A . n 
C 3 237 PHE 237 237 237 PHE PHE A . n 
C 3 238 LYS 238 238 238 LYS LYS A . n 
C 3 239 PRO 239 239 239 PRO PRO A . n 
C 3 240 LYS 240 240 240 LYS LYS A . n 
C 3 241 HIS 241 241 241 HIS HIS A . n 
C 3 242 VAL 242 242 242 VAL VAL A . n 
C 3 243 LYS 243 243 243 LYS LYS A . n 
C 3 244 ALA 244 244 244 ALA ALA A . n 
C 3 245 TRP 245 245 245 TRP TRP A . n 
C 3 246 VAL 246 246 246 VAL VAL A . n 
C 3 247 PRO 247 247 247 PRO PRO A . n 
C 3 248 ARG 248 248 248 ARG ARG A . n 
C 3 249 PRO 249 249 249 PRO PRO A . n 
C 3 250 PRO 250 250 250 PRO PRO A . n 
C 3 251 ARG 251 251 251 ARG ARG A . n 
C 3 252 LEU 252 252 252 LEU LEU A . n 
C 3 253 CYS 253 253 253 CYS CYS A . n 
C 3 254 GLN 254 254 254 GLN GLN A . n 
C 3 255 TYR 255 255 255 TYR TYR A . n 
C 3 256 GLU 256 256 256 GLU GLU A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 GLN 258 258 258 GLN GLN A . n 
C 3 259 LYS 259 259 259 LYS LYS A . n 
C 3 260 ASN 260 260 260 ASN ASN A . n 
C 3 261 VAL 261 261 261 VAL VAL A . n 
C 3 262 ASN 262 262 262 ASN ASN A . n 
C 3 263 PHE 263 263 263 PHE PHE A . n 
C 3 264 SER 264 264 264 SER SER A . n 
C 3 265 PRO 265 265 265 PRO PRO A . n 
C 3 266 ILE 266 266 266 ILE ILE A . n 
C 3 267 GLY 267 267 267 GLY GLY A . n 
C 3 268 VAL 268 268 268 VAL VAL A . n 
C 3 269 THR 269 269 269 THR THR A . n 
C 3 270 THR 270 270 270 THR THR A . n 
C 3 271 SER 271 271 271 SER SER A . n 
C 3 272 ARG 272 272 272 ARG ARG A . n 
C 3 273 THR 273 273 273 THR THR A . n 
C 3 274 ASP 274 274 274 ASP ASP A . n 
C 3 275 ILE 275 275 275 ILE ILE A . n 
C 3 276 ILE 276 276 276 ILE ILE A . n 
C 3 277 THR 277 277 ?   ?   ?   A . n 
C 3 278 THR 278 278 ?   ?   ?   A . n 
D 4 1   SER 1   1   ?   ?   ?   B . n 
D 4 2   PRO 2   2   ?   ?   ?   B . n 
D 4 3   SER 3   3   ?   ?   ?   B . n 
D 4 4   ALA 4   4   ?   ?   ?   B . n 
D 4 5   GLU 5   5   ?   ?   ?   B . n 
D 4 6   GLU 6   6   ?   ?   ?   B . n 
D 4 7   CYS 7   7   ?   ?   ?   B . n 
D 4 8   GLY 8   8   ?   ?   ?   B . n 
D 4 9   TYR 9   9   ?   ?   ?   B . n 
D 4 10  SER 10  10  ?   ?   ?   B . n 
D 4 11  ASP 11  11  ?   ?   ?   B . n 
D 4 12  ARG 12  12  ?   ?   ?   B . n 
D 4 13  VAL 13  13  ?   ?   ?   B . n 
D 4 14  ARG 14  14  14  ARG ARG B . n 
D 4 15  SER 15  15  15  SER SER B . n 
D 4 16  ILE 16  16  16  ILE ILE B . n 
D 4 17  THR 17  17  17  THR THR B . n 
D 4 18  LEU 18  18  18  LEU LEU B . n 
D 4 19  GLY 19  19  19  GLY GLY B . n 
D 4 20  ASN 20  20  20  ASN ASN B . n 
D 4 21  SER 21  21  21  SER SER B . n 
D 4 22  THR 22  22  22  THR THR B . n 
D 4 23  ILE 23  23  23  ILE ILE B . n 
D 4 24  THR 24  24  24  THR THR B . n 
D 4 25  THR 25  25  25  THR THR B . n 
D 4 26  GLN 26  26  26  GLN GLN B . n 
D 4 27  GLU 27  27  ?   ?   ?   B . n 
D 4 28  CYS 28  28  ?   ?   ?   B . n 
D 4 29  ALA 29  29  ?   ?   ?   B . n 
D 4 30  ASN 30  30  30  ASN ASN B . n 
D 4 31  VAL 31  31  31  VAL VAL B . n 
D 4 32  VAL 32  32  32  VAL VAL B . n 
D 4 33  VAL 33  33  33  VAL VAL B . n 
D 4 34  GLY 34  34  34  GLY GLY B . n 
D 4 35  TYR 35  35  35  TYR TYR B . n 
D 4 36  GLY 36  36  36  GLY GLY B . n 
D 4 37  VAL 37  37  37  VAL VAL B . n 
D 4 38  TRP 38  38  38  TRP TRP B . n 
D 4 39  PRO 39  39  39  PRO PRO B . n 
D 4 40  GLU 40  40  40  GLU GLU B . n 
D 4 41  TYR 41  41  41  TYR TYR B . n 
D 4 42  LEU 42  42  42  LEU LEU B . n 
D 4 43  LYS 43  43  ?   ?   ?   B . n 
D 4 44  ASP 44  44  ?   ?   ?   B . n 
D 4 45  ASN 45  45  ?   ?   ?   B . n 
D 4 46  GLU 46  46  ?   ?   ?   B . n 
D 4 47  ALA 47  47  ?   ?   ?   B . n 
D 4 48  THR 48  48  ?   ?   ?   B . n 
D 4 49  ALA 49  49  ?   ?   ?   B . n 
D 4 50  GLU 50  50  ?   ?   ?   B . n 
D 4 51  ASP 51  51  51  ASP ASP B . n 
D 4 52  GLN 52  52  52  GLN GLN B . n 
D 4 53  PRO 53  53  53  PRO PRO B . n 
D 4 54  THR 54  54  54  THR THR B . n 
D 4 55  GLN 55  55  55  GLN GLN B . n 
D 4 56  PRO 56  56  56  PRO PRO B . n 
D 4 57  ASP 57  57  57  ASP ASP B . n 
D 4 58  VAL 58  58  58  VAL VAL B . n 
D 4 59  ALA 59  59  59  ALA ALA B . n 
D 4 60  THR 60  60  60  THR THR B . n 
D 4 61  CYS 61  61  61  CYS CYS B . n 
D 4 62  ARG 62  62  62  ARG ARG B . n 
D 4 63  PHE 63  63  63  PHE PHE B . n 
D 4 64  TYR 64  64  64  TYR TYR B . n 
D 4 65  THR 65  65  65  THR THR B . n 
D 4 66  LEU 66  66  66  LEU LEU B . n 
D 4 67  GLU 67  67  67  GLU GLU B . n 
D 4 68  SER 68  68  68  SER SER B . n 
D 4 69  VAL 69  69  69  VAL VAL B . n 
D 4 70  GLN 70  70  70  GLN GLN B . n 
D 4 71  TRP 71  71  71  TRP TRP B . n 
D 4 72  MET 72  72  72  MET MET B . n 
D 4 73  LYS 73  73  73  LYS LYS B . n 
D 4 74  ASN 74  74  74  ASN ASN B . n 
D 4 75  SER 75  75  75  SER SER B . n 
D 4 76  ALA 76  76  76  ALA ALA B . n 
D 4 77  GLY 77  77  77  GLY GLY B . n 
D 4 78  TRP 78  78  78  TRP TRP B . n 
D 4 79  TRP 79  79  79  TRP TRP B . n 
D 4 80  TRP 80  80  80  TRP TRP B . n 
D 4 81  LYS 81  81  81  LYS LYS B . n 
D 4 82  LEU 82  82  82  LEU LEU B . n 
D 4 83  PRO 83  83  83  PRO PRO B . n 
D 4 84  ASP 84  84  84  ASP ASP B . n 
D 4 85  ALA 85  85  85  ALA ALA B . n 
D 4 86  LEU 86  86  86  LEU LEU B . n 
D 4 87  SER 87  87  87  SER SER B . n 
D 4 88  GLN 88  88  88  GLN GLN B . n 
D 4 89  MET 89  89  89  MET MET B . n 
D 4 90  GLY 90  90  90  GLY GLY B . n 
D 4 91  LEU 91  91  91  LEU LEU B . n 
D 4 92  PHE 92  92  92  PHE PHE B . n 
D 4 93  GLY 93  93  93  GLY GLY B . n 
D 4 94  GLN 94  94  94  GLN GLN B . n 
D 4 95  ASN 95  95  95  ASN ASN B . n 
D 4 96  MET 96  96  96  MET MET B . n 
D 4 97  GLN 97  97  97  GLN GLN B . n 
D 4 98  TYR 98  98  98  TYR TYR B . n 
D 4 99  HIS 99  99  99  HIS HIS B . n 
D 4 100 TYR 100 100 100 TYR TYR B . n 
D 4 101 LEU 101 101 101 LEU LEU B . n 
D 4 102 GLY 102 102 102 GLY GLY B . n 
D 4 103 ARG 103 103 103 ARG ARG B . n 
D 4 104 THR 104 104 104 THR THR B . n 
D 4 105 GLY 105 105 105 GLY GLY B . n 
D 4 106 TYR 106 106 106 TYR TYR B . n 
D 4 107 THR 107 107 107 THR THR B . n 
D 4 108 ILE 108 108 108 ILE ILE B . n 
D 4 109 HIS 109 109 109 HIS HIS B . n 
D 4 110 VAL 110 110 110 VAL VAL B . n 
D 4 111 GLN 111 111 111 GLN GLN B . n 
D 4 112 CYS 112 112 112 CYS CYS B . n 
D 4 113 ASN 113 113 113 ASN ASN B . n 
D 4 114 ALA 114 114 114 ALA ALA B . n 
D 4 115 SER 115 115 115 SER SER B . n 
D 4 116 LYS 116 116 116 LYS LYS B . n 
D 4 117 PHE 117 117 117 PHE PHE B . n 
D 4 118 HIS 118 118 118 HIS HIS B . n 
D 4 119 GLN 119 119 119 GLN GLN B . n 
D 4 120 GLY 120 120 120 GLY GLY B . n 
D 4 121 CYS 121 121 121 CYS CYS B . n 
D 4 122 LEU 122 122 122 LEU LEU B . n 
D 4 123 LEU 123 123 123 LEU LEU B . n 
D 4 124 VAL 124 124 124 VAL VAL B . n 
D 4 125 VAL 125 125 125 VAL VAL B . n 
D 4 126 CYS 126 126 126 CYS CYS B . n 
D 4 127 VAL 127 127 127 VAL VAL B . n 
D 4 128 PRO 128 128 128 PRO PRO B . n 
D 4 129 GLU 129 129 129 GLU GLU B . n 
D 4 130 ALA 130 130 130 ALA ALA B . n 
D 4 131 GLU 131 131 131 GLU GLU B . n 
D 4 132 MET 132 132 132 MET MET B . n 
D 4 133 GLY 133 133 133 GLY GLY B . n 
D 4 134 CYS 134 134 134 CYS CYS B . n 
D 4 135 SER 135 135 135 SER SER B . n 
D 4 136 ASN 136 136 136 ASN ASN B . n 
D 4 137 LEU 137 137 137 LEU LEU B . n 
D 4 138 ASN 138 138 138 ASN ASN B . n 
D 4 139 ASN 139 139 139 ASN ASN B . n 
D 4 140 THR 140 140 140 THR THR B . n 
D 4 141 PRO 141 141 141 PRO PRO B . n 
D 4 142 GLU 142 142 142 GLU GLU B . n 
D 4 143 PHE 143 143 143 PHE PHE B . n 
D 4 144 SER 144 144 144 SER SER B . n 
D 4 145 GLU 145 145 145 GLU GLU B . n 
D 4 146 LEU 146 146 146 LEU LEU B . n 
D 4 147 SER 147 147 147 SER SER B . n 
D 4 148 GLY 148 148 148 GLY GLY B . n 
D 4 149 GLY 149 149 149 GLY GLY B . n 
D 4 150 ASP 150 150 150 ASP ASP B . n 
D 4 151 SER 151 151 151 SER SER B . n 
D 4 152 ALA 152 152 152 ALA ALA B . n 
D 4 153 ARG 153 153 153 ARG ARG B . n 
D 4 154 MET 154 154 154 MET MET B . n 
D 4 155 PHE 155 155 155 PHE PHE B . n 
D 4 156 THR 156 156 156 THR THR B . n 
D 4 157 ASP 157 157 157 ASP ASP B . n 
D 4 158 THR 158 158 158 THR THR B . n 
D 4 159 GLN 159 159 159 GLN GLN B . n 
D 4 160 VAL 160 160 160 VAL VAL B . n 
D 4 161 GLY 161 161 161 GLY GLY B . n 
D 4 162 GLU 162 162 162 GLU GLU B . n 
D 4 163 SER 163 163 163 SER SER B . n 
D 4 164 ASN 164 164 164 ASN ASN B . n 
D 4 165 ALA 165 165 165 ALA ALA B . n 
D 4 166 LYS 166 166 166 LYS LYS B . n 
D 4 167 LYS 167 167 167 LYS LYS B . n 
D 4 168 VAL 168 168 168 VAL VAL B . n 
D 4 169 GLN 169 169 169 GLN GLN B . n 
D 4 170 THR 170 170 170 THR THR B . n 
D 4 171 ALA 171 171 171 ALA ALA B . n 
D 4 172 VAL 172 172 172 VAL VAL B . n 
D 4 173 TRP 173 173 173 TRP TRP B . n 
D 4 174 ASN 174 174 174 ASN ASN B . n 
D 4 175 ALA 175 175 175 ALA ALA B . n 
D 4 176 GLY 176 176 176 GLY GLY B . n 
D 4 177 MET 177 177 177 MET MET B . n 
D 4 178 GLY 178 178 178 GLY GLY B . n 
D 4 179 VAL 179 179 179 VAL VAL B . n 
D 4 180 GLY 180 180 180 GLY GLY B . n 
D 4 181 VAL 181 181 181 VAL VAL B . n 
D 4 182 GLY 182 182 182 GLY GLY B . n 
D 4 183 ASN 183 183 183 ASN ASN B . n 
D 4 184 LEU 184 184 184 LEU LEU B . n 
D 4 185 THR 185 185 185 THR THR B . n 
D 4 186 ILE 186 186 186 ILE ILE B . n 
D 4 187 PHE 187 187 187 PHE PHE B . n 
D 4 188 PRO 188 188 188 PRO PRO B . n 
D 4 189 HIS 189 189 189 HIS HIS B . n 
D 4 190 GLN 190 190 190 GLN GLN B . n 
D 4 191 TRP 191 191 191 TRP TRP B . n 
D 4 192 ILE 192 192 192 ILE ILE B . n 
D 4 193 ASN 193 193 193 ASN ASN B . n 
D 4 194 LEU 194 194 194 LEU LEU B . n 
D 4 195 ARG 195 195 195 ARG ARG B . n 
D 4 196 THR 196 196 196 THR THR B . n 
D 4 197 ASN 197 197 197 ASN ASN B . n 
D 4 198 ASN 198 198 198 ASN ASN B . n 
D 4 199 SER 199 199 199 SER SER B . n 
D 4 200 ALA 200 200 200 ALA ALA B . n 
D 4 201 THR 201 201 201 THR THR B . n 
D 4 202 LEU 202 202 202 LEU LEU B . n 
D 4 203 VAL 203 203 203 VAL VAL B . n 
D 4 204 MET 204 204 204 MET MET B . n 
D 4 205 PRO 205 205 205 PRO PRO B . n 
D 4 206 TYR 206 206 206 TYR TYR B . n 
D 4 207 ILE 207 207 207 ILE ILE B . n 
D 4 208 ASN 208 208 208 ASN ASN B . n 
D 4 209 SER 209 209 209 SER SER B . n 
D 4 210 VAL 210 210 210 VAL VAL B . n 
D 4 211 PRO 211 211 211 PRO PRO B . n 
D 4 212 MET 212 212 212 MET MET B . n 
D 4 213 ASP 213 213 213 ASP ASP B . n 
D 4 214 ASN 214 214 214 ASN ASN B . n 
D 4 215 MET 215 215 215 MET MET B . n 
D 4 216 PHE 216 216 216 PHE PHE B . n 
D 4 217 ARG 217 217 217 ARG ARG B . n 
D 4 218 HIS 218 218 218 HIS HIS B . n 
D 4 219 ASN 219 219 219 ASN ASN B . n 
D 4 220 ASN 220 220 220 ASN ASN B . n 
D 4 221 LEU 221 221 221 LEU LEU B . n 
D 4 222 THR 222 222 222 THR THR B . n 
D 4 223 LEU 223 223 223 LEU LEU B . n 
D 4 224 MET 224 224 224 MET MET B . n 
D 4 225 ILE 225 225 225 ILE ILE B . n 
D 4 226 ILE 226 226 226 ILE ILE B . n 
D 4 227 PRO 227 227 227 PRO PRO B . n 
D 4 228 PHE 228 228 228 PHE PHE B . n 
D 4 229 VAL 229 229 229 VAL VAL B . n 
D 4 230 PRO 230 230 230 PRO PRO B . n 
D 4 231 LEU 231 231 231 LEU LEU B . n 
D 4 232 ASN 232 232 232 ASN ASN B . n 
D 4 233 TYR 233 233 233 TYR TYR B . n 
D 4 234 SER 234 234 234 SER SER B . n 
D 4 235 GLU 235 235 235 GLU GLU B . n 
D 4 236 GLY 236 236 236 GLY GLY B . n 
D 4 237 SER 237 237 237 SER SER B . n 
D 4 238 SER 238 238 238 SER SER B . n 
D 4 239 PRO 239 239 239 PRO PRO B . n 
D 4 240 TYR 240 240 240 TYR TYR B . n 
D 4 241 VAL 241 241 241 VAL VAL B . n 
D 4 242 PRO 242 242 242 PRO PRO B . n 
D 4 243 ILE 243 243 243 ILE ILE B . n 
D 4 244 THR 244 244 244 THR THR B . n 
D 4 245 VAL 245 245 245 VAL VAL B . n 
D 4 246 THR 246 246 246 THR THR B . n 
D 4 247 ILE 247 247 247 ILE ILE B . n 
D 4 248 ALA 248 248 248 ALA ALA B . n 
D 4 249 PRO 249 249 249 PRO PRO B . n 
D 4 250 MET 250 250 250 MET MET B . n 
D 4 251 CYS 251 251 251 CYS CYS B . n 
D 4 252 ALA 252 252 252 ALA ALA B . n 
D 4 253 GLU 253 253 253 GLU GLU B . n 
D 4 254 TYR 254 254 254 TYR TYR B . n 
D 4 255 ASN 255 255 255 ASN ASN B . n 
D 4 256 GLY 256 256 256 GLY GLY B . n 
D 4 257 LEU 257 257 257 LEU LEU B . n 
D 4 258 ARG 258 258 ?   ?   ?   B . n 
D 4 259 LEU 259 259 ?   ?   ?   B . n 
D 4 260 ALA 260 260 ?   ?   ?   B . n 
D 4 261 SER 261 261 ?   ?   ?   B . n 
D 4 262 ASN 262 262 ?   ?   ?   B . n 
D 4 263 GLN 263 263 ?   ?   ?   B . n 
E 5 1   GLY 1   1   1   GLY GLY C . n 
E 5 2   LEU 2   2   2   LEU LEU C . n 
E 5 3   PRO 3   3   3   PRO PRO C . n 
E 5 4   VAL 4   4   4   VAL VAL C . n 
E 5 5   MET 5   5   5   MET MET C . n 
E 5 6   THR 6   6   6   THR THR C . n 
E 5 7   THR 7   7   7   THR THR C . n 
E 5 8   PRO 8   8   8   PRO PRO C . n 
E 5 9   GLY 9   9   9   GLY GLY C . n 
E 5 10  SER 10  10  10  SER SER C . n 
E 5 11  THR 11  11  11  THR THR C . n 
E 5 12  GLN 12  12  12  GLN GLN C . n 
E 5 13  PHE 13  13  13  PHE PHE C . n 
E 5 14  LEU 14  14  14  LEU LEU C . n 
E 5 15  THR 15  15  15  THR THR C . n 
E 5 16  SER 16  16  16  SER SER C . n 
E 5 17  ASP 17  17  17  ASP ASP C . n 
E 5 18  ASP 18  18  18  ASP ASP C . n 
E 5 19  PHE 19  19  19  PHE PHE C . n 
E 5 20  GLN 20  20  20  GLN GLN C . n 
E 5 21  SER 21  21  21  SER SER C . n 
E 5 22  PRO 22  22  22  PRO PRO C . n 
E 5 23  SER 23  23  23  SER SER C . n 
E 5 24  ALA 24  24  24  ALA ALA C . n 
E 5 25  MET 25  25  25  MET MET C . n 
E 5 26  PRO 26  26  26  PRO PRO C . n 
E 5 27  GLN 27  27  27  GLN GLN C . n 
E 5 28  PHE 28  28  28  PHE PHE C . n 
E 5 29  ASP 29  29  29  ASP ASP C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  THR 31  31  31  THR THR C . n 
E 5 32  PRO 32  32  32  PRO PRO C . n 
E 5 33  GLU 33  33  33  GLU GLU C . n 
E 5 34  MET 34  34  34  MET MET C . n 
E 5 35  GLN 35  35  35  GLN GLN C . n 
E 5 36  ILE 36  36  36  ILE ILE C . n 
E 5 37  PRO 37  37  37  PRO PRO C . n 
E 5 38  GLY 38  38  38  GLY GLY C . n 
E 5 39  ARG 39  39  39  ARG ARG C . n 
E 5 40  VAL 40  40  40  VAL VAL C . n 
E 5 41  ASN 41  41  41  ASN ASN C . n 
E 5 42  ASN 42  42  42  ASN ASN C . n 
E 5 43  LEU 43  43  43  LEU LEU C . n 
E 5 44  MET 44  44  44  MET MET C . n 
E 5 45  GLU 45  45  45  GLU GLU C . n 
E 5 46  ILE 46  46  46  ILE ILE C . n 
E 5 47  ALA 47  47  47  ALA ALA C . n 
E 5 48  GLU 48  48  48  GLU GLU C . n 
E 5 49  VAL 49  49  49  VAL VAL C . n 
E 5 50  ASP 50  50  50  ASP ASP C . n 
E 5 51  SER 51  51  51  SER SER C . n 
E 5 52  VAL 52  52  52  VAL VAL C . n 
E 5 53  VAL 53  53  53  VAL VAL C . n 
E 5 54  PRO 54  54  54  PRO PRO C . n 
E 5 55  VAL 55  55  55  VAL VAL C . n 
E 5 56  ASN 56  56  56  ASN ASN C . n 
E 5 57  ASN 57  57  57  ASN ASN C . n 
E 5 58  THR 58  58  58  THR THR C . n 
E 5 59  GLU 59  59  59  GLU GLU C . n 
E 5 60  ASP 60  60  60  ASP ASP C . n 
E 5 61  ASN 61  61  61  ASN ASN C . n 
E 5 62  VAL 62  62  62  VAL VAL C . n 
E 5 63  SER 63  63  63  SER SER C . n 
E 5 64  SER 64  64  64  SER SER C . n 
E 5 65  LEU 65  65  65  LEU LEU C . n 
E 5 66  LYS 66  66  66  LYS LYS C . n 
E 5 67  ALA 67  67  67  ALA ALA C . n 
E 5 68  TYR 68  68  68  TYR TYR C . n 
E 5 69  GLN 69  69  69  GLN GLN C . n 
E 5 70  ILE 70  70  70  ILE ILE C . n 
E 5 71  PRO 71  71  71  PRO PRO C . n 
E 5 72  VAL 72  72  72  VAL VAL C . n 
E 5 73  GLN 73  73  73  GLN GLN C . n 
E 5 74  SER 74  74  74  SER SER C . n 
E 5 75  ASN 75  75  75  ASN ASN C . n 
E 5 76  SER 76  76  76  SER SER C . n 
E 5 77  ASP 77  77  77  ASP ASP C . n 
E 5 78  ASN 78  78  78  ASN ASN C . n 
E 5 79  GLY 79  79  79  GLY GLY C . n 
E 5 80  LYS 80  80  80  LYS LYS C . n 
E 5 81  GLN 81  81  81  GLN GLN C . n 
E 5 82  VAL 82  82  82  VAL VAL C . n 
E 5 83  PHE 83  83  83  PHE PHE C . n 
E 5 84  GLY 84  84  84  GLY GLY C . n 
E 5 85  PHE 85  85  85  PHE PHE C . n 
E 5 86  PRO 86  86  86  PRO PRO C . n 
E 5 87  LEU 87  87  87  LEU LEU C . n 
E 5 88  GLN 88  88  88  GLN GLN C . n 
E 5 89  PRO 89  89  89  PRO PRO C . n 
E 5 90  GLY 90  90  90  GLY GLY C . n 
E 5 91  ALA 91  91  91  ALA ALA C . n 
E 5 92  ASN 92  92  92  ASN ASN C . n 
E 5 93  ASN 93  93  93  ASN ASN C . n 
E 5 94  VAL 94  94  94  VAL VAL C . n 
E 5 95  LEU 95  95  95  LEU LEU C . n 
E 5 96  ASN 96  96  96  ASN ASN C . n 
E 5 97  ARG 97  97  97  ARG ARG C . n 
E 5 98  THR 98  98  98  THR THR C . n 
E 5 99  LEU 99  99  99  LEU LEU C . n 
E 5 100 LEU 100 100 100 LEU LEU C . n 
E 5 101 GLY 101 101 101 GLY GLY C . n 
E 5 102 GLU 102 102 102 GLU GLU C . n 
E 5 103 ILE 103 103 103 ILE ILE C . n 
E 5 104 LEU 104 104 104 LEU LEU C . n 
E 5 105 ASN 105 105 105 ASN ASN C . n 
E 5 106 TYR 106 106 106 TYR TYR C . n 
E 5 107 TYR 107 107 107 TYR TYR C . n 
E 5 108 THR 108 108 108 THR THR C . n 
E 5 109 HIS 109 109 109 HIS HIS C . n 
E 5 110 TRP 110 110 110 TRP TRP C . n 
E 5 111 SER 111 111 111 SER SER C . n 
E 5 112 GLY 112 112 112 GLY GLY C . n 
E 5 113 SER 113 113 113 SER SER C . n 
E 5 114 ILE 114 114 114 ILE ILE C . n 
E 5 115 LYS 115 115 115 LYS LYS C . n 
E 5 116 LEU 116 116 116 LEU LEU C . n 
E 5 117 THR 117 117 117 THR THR C . n 
E 5 118 PHE 118 118 118 PHE PHE C . n 
E 5 119 MET 119 119 119 MET MET C . n 
E 5 120 PHE 120 120 120 PHE PHE C . n 
E 5 121 CYS 121 121 121 CYS CYS C . n 
E 5 122 GLY 122 122 122 GLY GLY C . n 
E 5 123 SER 123 123 123 SER SER C . n 
E 5 124 ALA 124 124 124 ALA ALA C . n 
E 5 125 MET 125 125 125 MET MET C . n 
E 5 126 ALA 126 126 126 ALA ALA C . n 
E 5 127 THR 127 127 127 THR THR C . n 
E 5 128 GLY 128 128 128 GLY GLY C . n 
E 5 129 LYS 129 129 129 LYS LYS C . n 
E 5 130 PHE 130 130 130 PHE PHE C . n 
E 5 131 LEU 131 131 131 LEU LEU C . n 
E 5 132 LEU 132 132 132 LEU LEU C . n 
E 5 133 ALA 133 133 133 ALA ALA C . n 
E 5 134 TYR 134 134 134 TYR TYR C . n 
E 5 135 SER 135 135 135 SER SER C . n 
E 5 136 PRO 136 136 136 PRO PRO C . n 
E 5 137 PRO 137 137 137 PRO PRO C . n 
E 5 138 GLY 138 138 138 GLY GLY C . n 
E 5 139 ALA 139 139 139 ALA ALA C . n 
E 5 140 GLY 140 140 140 GLY GLY C . n 
E 5 141 VAL 141 141 141 VAL VAL C . n 
E 5 142 PRO 142 142 142 PRO PRO C . n 
E 5 143 LYS 143 143 143 LYS LYS C . n 
E 5 144 ASN 144 144 144 ASN ASN C . n 
E 5 145 ARG 145 145 145 ARG ARG C . n 
E 5 146 LYS 146 146 146 LYS LYS C . n 
E 5 147 ASP 147 147 147 ASP ASP C . n 
E 5 148 ALA 148 148 148 ALA ALA C . n 
E 5 149 MET 149 149 149 MET MET C . n 
E 5 150 LEU 150 150 150 LEU LEU C . n 
E 5 151 GLY 151 151 151 GLY GLY C . n 
E 5 152 THR 152 152 152 THR THR C . n 
E 5 153 HIS 153 153 153 HIS HIS C . n 
E 5 154 VAL 154 154 154 VAL VAL C . n 
E 5 155 ILE 155 155 155 ILE ILE C . n 
E 5 156 TRP 156 156 156 TRP TRP C . n 
E 5 157 ASP 157 157 157 ASP ASP C . n 
E 5 158 VAL 158 158 158 VAL VAL C . n 
E 5 159 GLY 159 159 159 GLY GLY C . n 
E 5 160 LEU 160 160 160 LEU LEU C . n 
E 5 161 GLN 161 161 161 GLN GLN C . n 
E 5 162 SER 162 162 162 SER SER C . n 
E 5 163 SER 163 163 163 SER SER C . n 
E 5 164 CYS 164 164 164 CYS CYS C . n 
E 5 165 VAL 165 165 165 VAL VAL C . n 
E 5 166 LEU 166 166 166 LEU LEU C . n 
E 5 167 CYS 167 167 167 CYS CYS C . n 
E 5 168 VAL 168 168 168 VAL VAL C . n 
E 5 169 PRO 169 169 169 PRO PRO C . n 
E 5 170 TRP 170 170 170 TRP TRP C . n 
E 5 171 ILE 171 171 171 ILE ILE C . n 
E 5 172 SER 172 172 172 SER SER C . n 
E 5 173 GLN 173 173 ?   ?   ?   C . n 
E 5 174 THR 174 174 ?   ?   ?   C . n 
E 5 175 HIS 175 175 ?   ?   ?   C . n 
E 5 176 TYR 176 176 ?   ?   ?   C . n 
E 5 177 ARG 177 177 ?   ?   ?   C . n 
E 5 178 TYR 178 178 ?   ?   ?   C . n 
E 5 179 VAL 179 179 ?   ?   ?   C . n 
E 5 180 VAL 180 180 ?   ?   ?   C . n 
E 5 181 GLU 181 181 ?   ?   ?   C . n 
E 5 182 ASP 182 182 ?   ?   ?   C . n 
E 5 183 GLU 183 183 ?   ?   ?   C . n 
E 5 184 TYR 184 184 ?   ?   ?   C . n 
E 5 185 THR 185 185 ?   ?   ?   C . n 
E 5 186 ALA 186 186 186 ALA ALA C . n 
E 5 187 ALA 187 187 187 ALA ALA C . n 
E 5 188 GLY 188 188 188 GLY GLY C . n 
E 5 189 TYR 189 189 189 TYR TYR C . n 
E 5 190 VAL 190 190 190 VAL VAL C . n 
E 5 191 THR 191 191 191 THR THR C . n 
E 5 192 CYS 192 192 192 CYS CYS C . n 
E 5 193 TRP 193 193 193 TRP TRP C . n 
E 5 194 TYR 194 194 194 TYR TYR C . n 
E 5 195 GLN 195 195 195 GLN GLN C . n 
E 5 196 THR 196 196 196 THR THR C . n 
E 5 197 ASN 197 197 197 ASN ASN C . n 
E 5 198 ILE 198 198 198 ILE ILE C . n 
E 5 199 VAL 199 199 199 VAL VAL C . n 
E 5 200 VAL 200 200 200 VAL VAL C . n 
E 5 201 PRO 201 201 201 PRO PRO C . n 
E 5 202 ALA 202 202 202 ALA ALA C . n 
E 5 203 ASP 203 203 203 ASP ASP C . n 
E 5 204 VAL 204 204 204 VAL VAL C . n 
E 5 205 GLN 205 205 205 GLN GLN C . n 
E 5 206 SER 206 206 206 SER SER C . n 
E 5 207 SER 207 207 207 SER SER C . n 
E 5 208 CYS 208 208 208 CYS CYS C . n 
E 5 209 ASP 209 209 209 ASP ASP C . n 
E 5 210 ILE 210 210 210 ILE ILE C . n 
E 5 211 LEU 211 211 211 LEU LEU C . n 
E 5 212 CYS 212 212 212 CYS CYS C . n 
E 5 213 PHE 213 213 213 PHE PHE C . n 
E 5 214 VAL 214 214 214 VAL VAL C . n 
E 5 215 SER 215 215 215 SER SER C . n 
E 5 216 ALA 216 216 216 ALA ALA C . n 
E 5 217 CYS 217 217 217 CYS CYS C . n 
E 5 218 ASN 218 218 218 ASN ASN C . n 
E 5 219 ASP 219 219 219 ASP ASP C . n 
E 5 220 PHE 220 220 220 PHE PHE C . n 
E 5 221 SER 221 221 221 SER SER C . n 
E 5 222 VAL 222 222 222 VAL VAL C . n 
E 5 223 ARG 223 223 223 ARG ARG C . n 
E 5 224 MET 224 224 224 MET MET C . n 
E 5 225 LEU 225 225 225 LEU LEU C . n 
E 5 226 LYS 226 226 226 LYS LYS C . n 
E 5 227 ASP 227 227 227 ASP ASP C . n 
E 5 228 THR 228 228 228 THR THR C . n 
E 5 229 PRO 229 229 229 PRO PRO C . n 
E 5 230 PHE 230 230 230 PHE PHE C . n 
E 5 231 ILE 231 231 231 ILE ILE C . n 
E 5 232 ARG 232 232 232 ARG ARG C . n 
E 5 233 GLN 233 233 ?   ?   ?   C . n 
E 5 234 ASP 234 234 ?   ?   ?   C . n 
E 5 235 THR 235 235 ?   ?   ?   C . n 
E 5 236 PHE 236 236 ?   ?   ?   C . n 
E 5 237 TYR 237 237 ?   ?   ?   C . n 
E 5 238 GLN 238 238 ?   ?   ?   C . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              abing0811@xmu.edu.cn 
_pdbx_contact_author.name_first         Qingbing 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7516-9965 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     -0.80901699 -0.30901699 0.50000000  207.10319  0.50000000  -0.80901699 0.30901699  
0.00000    0.30901699  0.50000000  0.80901699  -542.20320 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  335.10000  0.80901700  0.30901699  -0.50000000 
127.99682  0.30901699  0.50000000  0.80901700  -207.10319 
3  'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901700  335.10000  0.50000000  -0.80901700 -0.30901700 
542.20320  0.80901699  0.30901700  0.50000000  -207.10319 
4  'point symmetry operation' ?     ?     -0.30901700 0.50000000  0.80901700  0.00000    -0.50000000 -0.80901699 0.30901700  
670.20001  0.80901700  -0.30901699 0.50000000  0.00000    
5  'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901700  -207.10319 -0.80901699 0.30901700  0.50000000  
335.10000  0.30901700  -0.50000000 0.80901699  127.99681  
6  'point symmetry operation' ?     ?     -0.80901699 0.30901700  0.50000001  335.10000  0.30901699  -0.50000000 0.80901699  
127.99681  0.49999999  0.80901700  0.30901699  -207.10319 
7  'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
8  'point symmetry operation' ?     ?     0.80901700  0.30901699  -0.50000000 127.99682  0.30901699  0.50000000  0.80901699  
-207.10320 0.50000000  -0.80901700 0.30901699  335.10001  
9  'point symmetry operation' ?     ?     0.50000000  -0.80901700 -0.30901699 542.20320  0.80901699  0.30901699  0.50000000  
-207.10319 -0.30901700 -0.50000000 0.80901699  335.10001  
10 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901700  670.20001  0.80901699  -0.30901700 0.50000000  
0.00000    -0.30901700 0.50000000  0.80901699  0.00000    
11 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  670.20001  -0.80901700 0.30901699  -0.49999999 
670.20002  0.30901700  -0.50000001 -0.80901699 670.20002  
12 'point symmetry operation' ?     ?     -0.80901700 0.30901700  0.50000000  335.10001  -0.30901700 0.50000000  -0.80901699 
542.20320  -0.50000000 -0.80901700 -0.30901699 877.30321  
13 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
670.20002  -1.00000000 0.00000000  0.00000000  670.20001  
14 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 127.99682  -0.30901699 -0.50000000 -0.80901700 
877.30321  -0.50000000 0.80901700  -0.30901699 335.10001  
15 'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901700 542.20320  -0.80901699 -0.30901700 -0.50000000 
877.30321  0.30901700  0.50000000  -0.80901699 335.10001  
16 'point symmetry operation' ?     ?     0.30901699  0.49999999  -0.80901700 335.10001  0.50000001  -0.80901699 -0.30901700 
542.20320  -0.80901699 -0.30901699 -0.50000000 877.30321  
17 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901700 670.20002  -0.50000000 -0.80901699 0.30901699  
670.20001  -0.80901699 0.30901700  -0.50000000 670.20002  
18 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901700 877.30321  -0.80901700 0.30901699  0.50000000  
335.10001  -0.30901699 0.50000000  -0.80901699 542.20321  
19 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  670.20001  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 670.20002  
20 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901700 335.10001  0.80901699  0.30901700  -0.50000000 
127.99682  -0.30901700 -0.50000000 -0.80901699 877.30321  
21 'point symmetry operation' ?     ?     -0.49999999 -0.80901700 -0.30901699 877.30321  0.80901699  -0.30901700 -0.50000001 
335.10001  0.30901699  -0.50000000 0.80901699  127.99681  
22 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  670.20001  0.00000000  -1.00000000 0.00000000  
670.20002  0.00000000  0.00000000  1.00000000  0.00000    
23 'point symmetry operation' ?     ?     -0.50000000 0.80901700  -0.30901699 335.10001  -0.80901700 -0.30901699 0.50000000  
542.20320  0.30901699  0.50000000  0.80901699  -207.10319 
24 'point symmetry operation' ?     ?     0.30901700  0.50000000  -0.80901699 335.10001  -0.50000000 0.80901700  0.30901699  
127.99681  0.80901699  0.30901699  0.50000000  -207.10319 
25 'point symmetry operation' ?     ?     0.30901700  -0.50000000 -0.80901699 670.20001  0.50000000  0.80901699  -0.30901700 
0.00000    0.80901699  -0.30901700 0.50000000  0.00000    
26 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 670.20002  -1.00000000 0.00000000  0.00000000  
670.20001  0.00000000  1.00000000  0.00000000  0.00000    
27 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901700 877.30321  -0.50000000 0.80901699  -0.30901699 
335.10001  0.80901700  0.30901699  -0.50000000 127.99682  
28 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 -0.50000000 877.30321  0.30901699  0.50000000  -0.80901700 
335.10001  0.50000000  -0.80901700 -0.30901700 542.20321  
29 'point symmetry operation' ?     ?     -0.80901700 0.30901699  -0.50000000 670.20002  0.30901700  -0.50000000 -0.80901700 
670.20002  -0.50000000 -0.80901699 0.30901700  670.20001  
30 'point symmetry operation' ?     ?     -0.30901700 0.50000000  -0.80901699 542.20320  -0.50000000 -0.80901699 -0.30901700 
877.30321  -0.80901699 0.30901700  0.50000000  335.10000  
31 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  -207.10319 -0.30901699 -0.49999999 0.80901700  
335.10000  0.50000001  -0.80901699 -0.30901700 542.20320  
32 'point symmetry operation' ?     ?     0.80901699  -0.30901700 0.50000000  0.00000    -0.30901699 0.50000000  0.80901700  
0.00000    -0.50000000 -0.80901699 0.30901699  670.20001  
33 'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  127.99681  0.50000000  0.80901699  0.30901700  
-207.10319 -0.80901700 0.30901699  0.50000000  335.10001  
34 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
35 'point symmetry operation' ?     ?     0.30901700  0.50000000  0.80901699  -207.10320 0.50000000  -0.80901699 0.30901700  
335.10001  0.80901699  0.30901700  -0.50000000 127.99682  
36 'point symmetry operation' ?     ?     -0.30901700 0.50000001  0.80901699  0.00000    0.50000000  0.80901699  -0.30901699 
0.00000    -0.80901700 0.30901699  -0.49999999 670.20002  
37 'point symmetry operation' ?     ?     0.50000000  0.80901700  0.30901699  -207.10319 0.80901700  -0.30901700 -0.50000000 
335.10001  -0.30901700 0.50000000  -0.80901699 542.20320  
38 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
670.20001  0.00000000  0.00000000  -1.00000000 670.20002  
39 'point symmetry operation' ?     ?     0.50000000  -0.80901700 0.30901699  335.10001  -0.80901699 -0.30901699 0.50000000  
542.20320  -0.30901699 -0.50000000 -0.80901700 877.30321  
40 'point symmetry operation' ?     ?     -0.30901700 -0.50000000 0.80901699  335.10001  -0.50000000 0.80901699  0.30901700  
127.99681  -0.80901699 -0.30901700 -0.50000000 877.30321  
41 'point symmetry operation' ?     ?     -0.50000001 0.80901699  0.30901700  127.99681  -0.80901699 -0.30901699 -0.50000000 
877.30321  -0.30901699 -0.49999999 0.80901700  335.10000  
42 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000    -0.80901699 0.30901700  -0.50000000 
670.20001  -0.30901699 0.50000000  0.80901700  0.00000    
43 'point symmetry operation' ?     ?     0.80901700  -0.30901699 -0.50000000 335.10001  -0.30901699 0.50000000  -0.80901699 
542.20320  0.50000000  0.80901699  0.30901700  -207.10319 
44 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  670.20001  0.00000000  0.00000000  -1.00000000 
670.20002  1.00000000  0.00000000  0.00000000  0.00000    
45 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 0.50000000  542.20320  -0.30901700 -0.50000000 -0.80901699 
877.30321  0.50000000  -0.80901699 0.30901700  335.10001  
46 'point symmetry operation' ?     ?     0.80901700  -0.30901699 0.49999999  0.00000    0.30901700  -0.50000001 -0.80901699 
670.20002  0.50000000  0.80901699  -0.30901699 0.00000    
47 'point symmetry operation' ?     ?     0.30901700  -0.50000000 0.80901699  127.99681  -0.50000000 -0.80901700 -0.30901699 
877.30321  0.80901700  -0.30901700 -0.50000000 335.10001  
48 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
670.20001  0.00000000  -1.00000000 0.00000000  670.20001  
49 'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901700  -207.10320 -0.50000000 0.80901700  -0.30901699 
335.10001  -0.80901699 -0.30901699 0.50000000  542.20320  
50 'point symmetry operation' ?     ?     0.80901699  0.30901700  0.50000000  -207.10319 0.30901700  0.50000000  -0.80901699 
335.10001  -0.50000000 0.80901699  0.30901700  127.99681  
51 'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 542.20320  0.49999999  0.80901700  0.30901699  
-207.10319 0.80901699  -0.30901700 -0.50000001 335.10001  
52 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 670.20002  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  670.20002  
53 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 877.30321  0.50000000  -0.80901700 0.30901699  
335.10001  -0.80901700 -0.30901699 0.50000000  542.20320  
54 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 877.30321  -0.30901700 -0.50000000 0.80901699  
335.10001  -0.50000000 0.80901700  0.30901699  127.99681  
55 'point symmetry operation' ?     ?     -0.80901699 0.30901700  -0.50000000 670.20001  -0.30901700 0.50000000  0.80901699  
0.00000    0.50000000  0.80901699  -0.30901700 0.00000    
56 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  670.20001  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  670.20002  
57 'point symmetry operation' ?     ?     -0.80901700 -0.30901699 0.50000000  542.20320  0.30901699  0.50000000  0.80901700  
-207.10319 -0.50000000 0.80901699  -0.30901699 335.10001  
58 'point symmetry operation' ?     ?     -0.50000000 0.80901700  0.30901700  127.99681  0.80901699  0.30901700  0.50000000  
-207.10319 0.30901699  0.50000000  -0.80901700 335.10001  
59 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901700 0.00000    0.80901700  -0.30901699 0.50000000  
0.00000    0.30901700  -0.50000000 -0.80901700 670.20002  
60 'point symmetry operation' ?     ?     0.80901699  -0.30901700 -0.50000000 335.10001  0.30901700  -0.50000000 0.80901699  
127.99681  -0.50000000 -0.80901699 -0.30901700 877.30321  
# 
_pdbx_point_symmetry.entry_id             7X3Y 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2023-06-07 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          7X3Y 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    7X3Y 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.32 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               10464 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        7X3Y 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TECNAI F30' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1100 
_em_imaging.nominal_defocus_max             3300 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              7X3Y 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                7X3Y 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             B 
_pdbx_validate_rmsd_angle.auth_comp_id_1             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_1              251 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             B 
_pdbx_validate_rmsd_angle.auth_comp_id_2             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_2              251 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             SG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             B 
_pdbx_validate_rmsd_angle.auth_comp_id_3             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_3              251 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                122.25 
_pdbx_validate_rmsd_angle.angle_target_value         114.20 
_pdbx_validate_rmsd_angle.angle_deviation            8.05 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG H 89  ? ? -119.00 -169.63 
2  1 TYR H 110 ? ? -90.61  31.28   
3  1 THR L 52  ? ? 65.13   -6.75   
4  1 SER L 53  ? ? -141.17 -6.72   
5  1 ALA L 56  ? ? -79.75  -167.75 
6  1 ARG A 95  ? ? -96.97  33.04   
7  1 ALA A 129 ? ? -172.14 -174.21 
8  1 SER A 130 ? ? 60.36   65.62   
9  1 SER A 131 ? ? 62.10   67.33   
10 1 ASN A 208 ? ? 58.68   76.24   
11 1 THR A 209 ? ? -61.19  4.45    
12 1 VAL A 246 ? ? 55.10   80.63   
13 1 GLU A 256 ? ? -101.94 -60.27  
14 1 TYR B 35  ? ? -99.47  37.01   
15 1 ASN B 74  ? ? -92.57  46.94   
16 1 PRO B 83  ? ? -88.21  39.80   
17 1 MET B 212 ? ? -163.45 119.23  
18 1 SER C 10  ? ? -97.82  -64.92  
19 1 THR C 11  ? ? -96.84  55.71   
20 1 ASP C 29  ? ? 58.87   71.86   
21 1 THR C 58  ? ? 47.37   23.10   
22 1 GLU C 59  ? ? 67.23   -0.93   
23 1 SER C 63  ? ? -95.10  55.14   
24 1 SER C 111 ? ? -162.06 116.64  
25 1 ASN C 218 ? ? 78.75   -9.79   
26 1 MET C 224 ? ? 60.78   74.88   
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     L 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     ALA 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      101 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     CB 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    B 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    ALA 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     101 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    CB 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 L GLU 1   ? B GLU 1   
2   1 Y 1 A GLY 1   ? C GLY 1   
3   1 Y 1 A PRO 2   ? C PRO 2   
4   1 Y 1 A VAL 3   ? C VAL 3   
5   1 Y 1 A GLU 4   ? C GLU 4   
6   1 Y 1 A GLU 5   ? C GLU 5   
7   1 Y 1 A SER 6   ? C SER 6   
8   1 Y 1 A VAL 7   ? C VAL 7   
9   1 Y 1 A ASP 8   ? C ASP 8   
10  1 Y 1 A ARG 9   ? C ARG 9   
11  1 Y 1 A ALA 10  ? C ALA 10  
12  1 Y 1 A VAL 11  ? C VAL 11  
13  1 Y 1 A ALA 12  ? C ALA 12  
14  1 Y 1 A ARG 13  ? C ARG 13  
15  1 Y 1 A VAL 14  ? C VAL 14  
16  1 Y 1 A ALA 15  ? C ALA 15  
17  1 Y 1 A ASP 16  ? C ASP 16  
18  1 Y 1 A THR 17  ? C THR 17  
19  1 Y 1 A ILE 18  ? C ILE 18  
20  1 Y 1 A SER 19  ? C SER 19  
21  1 Y 1 A SER 20  ? C SER 20  
22  1 Y 1 A ARG 21  ? C ARG 21  
23  1 Y 1 A PRO 22  ? C PRO 22  
24  1 Y 1 A THR 23  ? C THR 23  
25  1 Y 1 A ASN 24  ? C ASN 24  
26  1 Y 1 A SER 25  ? C SER 25  
27  1 Y 1 A GLU 26  ? C GLU 26  
28  1 Y 1 A SER 27  ? C SER 27  
29  1 Y 1 A ILE 28  ? C ILE 28  
30  1 Y 1 A PRO 29  ? C PRO 29  
31  1 Y 1 A ALA 30  ? C ALA 30  
32  1 Y 1 A LEU 31  ? C LEU 31  
33  1 Y 1 A THR 32  ? C THR 32  
34  1 Y 1 A ALA 33  ? C ALA 33  
35  1 Y 1 A ALA 34  ? C ALA 34  
36  1 Y 1 A GLU 35  ? C GLU 35  
37  1 Y 1 A THR 36  ? C THR 36  
38  1 Y 1 A GLY 37  ? C GLY 37  
39  1 Y 1 A HIS 38  ? C HIS 38  
40  1 Y 1 A THR 39  ? C THR 39  
41  1 Y 1 A SER 40  ? C SER 40  
42  1 Y 1 A GLN 41  ? C GLN 41  
43  1 Y 1 A VAL 42  ? C VAL 42  
44  1 Y 1 A VAL 43  ? C VAL 43  
45  1 Y 1 A PRO 44  ? C PRO 44  
46  1 Y 1 A SER 45  ? C SER 45  
47  1 Y 1 A ASP 46  ? C ASP 46  
48  1 Y 1 A THR 47  ? C THR 47  
49  1 Y 1 A MET 48  ? C MET 48  
50  1 Y 1 A GLN 49  ? C GLN 49  
51  1 Y 1 A THR 50  ? C THR 50  
52  1 Y 1 A ARG 51  ? C ARG 51  
53  1 Y 1 A HIS 52  ? C HIS 52  
54  1 Y 1 A VAL 53  ? C VAL 53  
55  1 Y 1 A LYS 54  ? C LYS 54  
56  1 Y 1 A ASN 55  ? C ASN 55  
57  1 Y 1 A TYR 56  ? C TYR 56  
58  1 Y 1 A HIS 57  ? C HIS 57  
59  1 Y 1 A GLN 198 ? C GLN 198 
60  1 Y 1 A PHE 199 ? C PHE 199 
61  1 Y 1 A SER 200 ? C SER 200 
62  1 Y 1 A ARG 201 ? C ARG 201 
63  1 Y 1 A ASN 202 ? C ASN 202 
64  1 Y 1 A GLY 203 ? C GLY 203 
65  1 Y 1 A THR 277 ? C THR 277 
66  1 Y 1 A THR 278 ? C THR 278 
67  1 Y 1 B SER 1   ? D SER 1   
68  1 Y 1 B PRO 2   ? D PRO 2   
69  1 Y 1 B SER 3   ? D SER 3   
70  1 Y 1 B ALA 4   ? D ALA 4   
71  1 Y 1 B GLU 5   ? D GLU 5   
72  1 Y 1 B GLU 6   ? D GLU 6   
73  1 Y 1 B CYS 7   ? D CYS 7   
74  1 Y 1 B GLY 8   ? D GLY 8   
75  1 Y 1 B TYR 9   ? D TYR 9   
76  1 Y 1 B SER 10  ? D SER 10  
77  1 Y 1 B ASP 11  ? D ASP 11  
78  1 Y 1 B ARG 12  ? D ARG 12  
79  1 Y 1 B VAL 13  ? D VAL 13  
80  1 Y 1 B GLU 27  ? D GLU 27  
81  1 Y 1 B CYS 28  ? D CYS 28  
82  1 Y 1 B ALA 29  ? D ALA 29  
83  1 Y 1 B LYS 43  ? D LYS 43  
84  1 Y 1 B ASP 44  ? D ASP 44  
85  1 Y 1 B ASN 45  ? D ASN 45  
86  1 Y 1 B GLU 46  ? D GLU 46  
87  1 Y 1 B ALA 47  ? D ALA 47  
88  1 Y 1 B THR 48  ? D THR 48  
89  1 Y 1 B ALA 49  ? D ALA 49  
90  1 Y 1 B GLU 50  ? D GLU 50  
91  1 Y 1 B ARG 258 ? D ARG 258 
92  1 Y 1 B LEU 259 ? D LEU 259 
93  1 Y 1 B ALA 260 ? D ALA 260 
94  1 Y 1 B SER 261 ? D SER 261 
95  1 Y 1 B ASN 262 ? D ASN 262 
96  1 Y 1 B GLN 263 ? D GLN 263 
97  1 Y 1 C GLN 173 ? E GLN 173 
98  1 Y 1 C THR 174 ? E THR 174 
99  1 Y 1 C HIS 175 ? E HIS 175 
100 1 Y 1 C TYR 176 ? E TYR 176 
101 1 Y 1 C ARG 177 ? E ARG 177 
102 1 Y 1 C TYR 178 ? E TYR 178 
103 1 Y 1 C VAL 179 ? E VAL 179 
104 1 Y 1 C VAL 180 ? E VAL 180 
105 1 Y 1 C GLU 181 ? E GLU 181 
106 1 Y 1 C ASP 182 ? E ASP 182 
107 1 Y 1 C GLU 183 ? E GLU 183 
108 1 Y 1 C TYR 184 ? E TYR 184 
109 1 Y 1 C THR 185 ? E THR 185 
110 1 Y 1 C GLN 233 ? E GLN 233 
111 1 Y 1 C ASP 234 ? E ASP 234 
112 1 Y 1 C THR 235 ? E THR 235 
113 1 Y 1 C PHE 236 ? E PHE 236 
114 1 Y 1 C TYR 237 ? E TYR 237 
115 1 Y 1 C GLN 238 ? E GLN 238 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          12071 
_em_entity_assembly_naturalsource.organism             'Coxsackievirus B1' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          10029 
_em_entity_assembly_recombinant.organism             'Cricetulus griseus' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       INTEGRATING 
_em_image_recording.film_or_detector_model              'FEI FALCON II (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'CRYSTALLOGRAPHY MERGING'       ? 1  1 1 1 ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'PARTICLE SELECTION'            ? 14 1 1 1 ? ? 
'VOLUME SELECTION'              ? 15 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 16 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 17 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 18 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
