data_7X4K
# 
_entry.id   7X4K 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.360 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7X4K         pdb_00007x4k 10.2210/pdb7x4k/pdb 
WWPDB D_1300027924 ?            ?                   
EMDB  EMD-33004    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (classified from CVB1 mature virion in complex with 8A10 and 9A3)
;
_pdbx_database_related.db_id          EMD-33004 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7X4K 
_pdbx_database_status.recvd_initial_deposition_date   2022-03-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zheng, Q.' 1 ? 
'Zhu, R.'   2 ? 
'Sun, H.'   3 ? 
'Cheng, T.' 4 ? 
'Li, S.'    5 ? 
'Xia, N.'   6 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Host Microbe' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1934-6069 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            30 
_citation.language                  ? 
_citation.page_first                1279 
_citation.page_last                 1294.e6 
_citation.title                     
'Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.' 
_citation.year                      2022 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.chom.2022.08.001 
_citation.pdbx_database_id_PubMed   36002016 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zheng, Q.' 1  ? 
primary 'Zhu, R.'   2  ? 
primary 'Yin, Z.'   3  ? 
primary 'Xu, L.'    4  ? 
primary 'Sun, H.'   5  ? 
primary 'Yu, H.'    6  ? 
primary 'Wu, Y.'    7  ? 
primary 'Jiang, Y.' 8  ? 
primary 'Huang, Q.' 9  ? 
primary 'Huang, Y.' 10 ? 
primary 'Zhang, D.' 11 ? 
primary 'Liu, L.'   12 ? 
primary 'Yang, H.'  13 ? 
primary 'He, M.'    14 ? 
primary 'Zhou, Z.'  15 ? 
primary 'Jiang, Y.' 16 ? 
primary 'Chen, Z.'  17 ? 
primary 'Zhao, H.'  18 ? 
primary 'Que, Y.'   19 ? 
primary 'Kong, Z.'  20 ? 
primary 'Zhou, L.'  21 ? 
primary 'Li, T.'    22 ? 
primary 'Zhang, J.' 23 ? 
primary 'Luo, W.'   24 ? 
primary 'Gu, Y.'    25 ? 
primary 'Cheng, T.' 26 ? 
primary 'Li, S.'    27 ? 
primary 'Xia, N.'   28 ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7X4K 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         7X4K 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer nat '9A3 heavy chain'    13768.251 1 ?                                     ? ? ? 
2 polymer nat '9A3 light chain'    11472.680 1 ?                                     ? ? ? 
3 polymer nat 'Virion protein 1'   31207.117 1 ?                                     ? ? ? 
4 polymer nat 'Genome polyprotein' 29122.744 1 ?                                     ? ? ? 
5 polymer nat VP3                  26328.764 1 3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48 ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
3 'VP1, P1C,P1D' 
4 'CVB1 VP2'     
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVKLVESGGGLVQPGGSLSLSCAASGFTFTDYYMNWVRQPSGKALEWLGFLRNKANGYTTEYSASVKGRFTISRDNSQSI
LYLQMNALRAEDSATYYCARSRYYGGTYRYALDYWGQGTSVTVS
;
;EVKLVESGGGLVQPGGSLSLSCAASGFTFTDYYMNWVRQPSGKALEWLGFLRNKANGYTTEYSASVKGRFTISRDNSQSI
LYLQMNALRAEDSATYYCARSRYYGGTYRYALDYWGQGTSVTVS
;
H ? 
2 'polypeptide(L)' no no 
;ENVLTQSPPIMSASPGEKVTMTCRASSSVSSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGAGTKLELK
;
;ENVLTQSPPIMSASPGEKVTMTCRASSSVSSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE
AEDAATYYCQQFSGYPLTFGAGTKLELK
;
L ? 
3 'polypeptide(L)' no no 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSKKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
A ? 
4 'polypeptide(L)' no no 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
B ? 
5 'polypeptide(L)' no no 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   LYS n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  SER n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  ALA n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  THR n 
1 29  PHE n 
1 30  THR n 
1 31  ASP n 
1 32  TYR n 
1 33  TYR n 
1 34  MET n 
1 35  ASN n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  PRO n 
1 41  SER n 
1 42  GLY n 
1 43  LYS n 
1 44  ALA n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  LEU n 
1 49  GLY n 
1 50  PHE n 
1 51  LEU n 
1 52  ARG n 
1 53  ASN n 
1 54  LYS n 
1 55  ALA n 
1 56  ASN n 
1 57  GLY n 
1 58  TYR n 
1 59  THR n 
1 60  THR n 
1 61  GLU n 
1 62  TYR n 
1 63  SER n 
1 64  ALA n 
1 65  SER n 
1 66  VAL n 
1 67  LYS n 
1 68  GLY n 
1 69  ARG n 
1 70  PHE n 
1 71  THR n 
1 72  ILE n 
1 73  SER n 
1 74  ARG n 
1 75  ASP n 
1 76  ASN n 
1 77  SER n 
1 78  GLN n 
1 79  SER n 
1 80  ILE n 
1 81  LEU n 
1 82  TYR n 
1 83  LEU n 
1 84  GLN n 
1 85  MET n 
1 86  ASN n 
1 87  ALA n 
1 88  LEU n 
1 89  ARG n 
1 90  ALA n 
1 91  GLU n 
1 92  ASP n 
1 93  SER n 
1 94  ALA n 
1 95  THR n 
1 96  TYR n 
1 97  TYR n 
1 98  CYS n 
1 99  ALA n 
1 100 ARG n 
1 101 SER n 
1 102 ARG n 
1 103 TYR n 
1 104 TYR n 
1 105 GLY n 
1 106 GLY n 
1 107 THR n 
1 108 TYR n 
1 109 ARG n 
1 110 TYR n 
1 111 ALA n 
1 112 LEU n 
1 113 ASP n 
1 114 TYR n 
1 115 TRP n 
1 116 GLY n 
1 117 GLN n 
1 118 GLY n 
1 119 THR n 
1 120 SER n 
1 121 VAL n 
1 122 THR n 
1 123 VAL n 
1 124 SER n 
2 1   GLU n 
2 2   ASN n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   PRO n 
2 10  ILE n 
2 11  MET n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  PRO n 
2 16  GLY n 
2 17  GLU n 
2 18  LYS n 
2 19  VAL n 
2 20  THR n 
2 21  MET n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  SER n 
2 28  SER n 
2 29  VAL n 
2 30  SER n 
2 31  SER n 
2 32  SER n 
2 33  TYR n 
2 34  LEU n 
2 35  HIS n 
2 36  TRP n 
2 37  TYR n 
2 38  GLN n 
2 39  GLN n 
2 40  LYS n 
2 41  SER n 
2 42  GLY n 
2 43  ALA n 
2 44  SER n 
2 45  PRO n 
2 46  LYS n 
2 47  LEU n 
2 48  TRP n 
2 49  ILE n 
2 50  TYR n 
2 51  SER n 
2 52  THR n 
2 53  SER n 
2 54  ASN n 
2 55  LEU n 
2 56  ALA n 
2 57  SER n 
2 58  GLY n 
2 59  VAL n 
2 60  PRO n 
2 61  ALA n 
2 62  ARG n 
2 63  PHE n 
2 64  SER n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  SER n 
2 69  GLY n 
2 70  THR n 
2 71  SER n 
2 72  TYR n 
2 73  SER n 
2 74  LEU n 
2 75  THR n 
2 76  ILE n 
2 77  SER n 
2 78  SER n 
2 79  VAL n 
2 80  GLU n 
2 81  ALA n 
2 82  GLU n 
2 83  ASP n 
2 84  ALA n 
2 85  ALA n 
2 86  THR n 
2 87  TYR n 
2 88  TYR n 
2 89  CYS n 
2 90  GLN n 
2 91  GLN n 
2 92  PHE n 
2 93  SER n 
2 94  GLY n 
2 95  TYR n 
2 96  PRO n 
2 97  LEU n 
2 98  THR n 
2 99  PHE n 
2 100 GLY n 
2 101 ALA n 
2 102 GLY n 
2 103 THR n 
2 104 LYS n 
2 105 LEU n 
2 106 GLU n 
2 107 LEU n 
2 108 LYS n 
3 1   GLY n 
3 2   PRO n 
3 3   VAL n 
3 4   GLU n 
3 5   GLU n 
3 6   SER n 
3 7   VAL n 
3 8   ASP n 
3 9   ARG n 
3 10  ALA n 
3 11  VAL n 
3 12  ALA n 
3 13  ARG n 
3 14  VAL n 
3 15  ALA n 
3 16  ASP n 
3 17  THR n 
3 18  ILE n 
3 19  SER n 
3 20  SER n 
3 21  ARG n 
3 22  PRO n 
3 23  THR n 
3 24  ASN n 
3 25  SER n 
3 26  GLU n 
3 27  SER n 
3 28  ILE n 
3 29  PRO n 
3 30  ALA n 
3 31  LEU n 
3 32  THR n 
3 33  ALA n 
3 34  ALA n 
3 35  GLU n 
3 36  THR n 
3 37  GLY n 
3 38  HIS n 
3 39  THR n 
3 40  SER n 
3 41  GLN n 
3 42  VAL n 
3 43  VAL n 
3 44  PRO n 
3 45  SER n 
3 46  ASP n 
3 47  THR n 
3 48  MET n 
3 49  GLN n 
3 50  THR n 
3 51  ARG n 
3 52  HIS n 
3 53  VAL n 
3 54  LYS n 
3 55  ASN n 
3 56  TYR n 
3 57  HIS n 
3 58  SER n 
3 59  ARG n 
3 60  SER n 
3 61  GLU n 
3 62  SER n 
3 63  SER n 
3 64  ILE n 
3 65  GLU n 
3 66  ASN n 
3 67  PHE n 
3 68  LEU n 
3 69  CYS n 
3 70  ARG n 
3 71  SER n 
3 72  ALA n 
3 73  CYS n 
3 74  VAL n 
3 75  TYR n 
3 76  TYR n 
3 77  ALA n 
3 78  THR n 
3 79  TYR n 
3 80  THR n 
3 81  ASN n 
3 82  ASN n 
3 83  SER n 
3 84  LYS n 
3 85  LYS n 
3 86  GLY n 
3 87  PHE n 
3 88  ALA n 
3 89  GLU n 
3 90  TRP n 
3 91  VAL n 
3 92  ILE n 
3 93  ASN n 
3 94  THR n 
3 95  ARG n 
3 96  GLN n 
3 97  VAL n 
3 98  ALA n 
3 99  GLN n 
3 100 LEU n 
3 101 ARG n 
3 102 ARG n 
3 103 LYS n 
3 104 LEU n 
3 105 GLU n 
3 106 LEU n 
3 107 PHE n 
3 108 THR n 
3 109 TYR n 
3 110 LEU n 
3 111 ARG n 
3 112 PHE n 
3 113 ASP n 
3 114 LEU n 
3 115 GLU n 
3 116 LEU n 
3 117 THR n 
3 118 PHE n 
3 119 VAL n 
3 120 ILE n 
3 121 THR n 
3 122 SER n 
3 123 ALA n 
3 124 GLN n 
3 125 GLN n 
3 126 PRO n 
3 127 SER n 
3 128 THR n 
3 129 ALA n 
3 130 SER n 
3 131 SER n 
3 132 VAL n 
3 133 ASP n 
3 134 ALA n 
3 135 PRO n 
3 136 VAL n 
3 137 GLN n 
3 138 THR n 
3 139 HIS n 
3 140 GLN n 
3 141 ILE n 
3 142 MET n 
3 143 TYR n 
3 144 VAL n 
3 145 PRO n 
3 146 PRO n 
3 147 GLY n 
3 148 GLY n 
3 149 PRO n 
3 150 VAL n 
3 151 PRO n 
3 152 THR n 
3 153 LYS n 
3 154 VAL n 
3 155 LYS n 
3 156 ASP n 
3 157 TYR n 
3 158 ALA n 
3 159 TRP n 
3 160 GLN n 
3 161 THR n 
3 162 SER n 
3 163 THR n 
3 164 ASN n 
3 165 PRO n 
3 166 SER n 
3 167 VAL n 
3 168 PHE n 
3 169 TRP n 
3 170 THR n 
3 171 GLU n 
3 172 GLY n 
3 173 ASN n 
3 174 ALA n 
3 175 PRO n 
3 176 PRO n 
3 177 ARG n 
3 178 MET n 
3 179 SER n 
3 180 ILE n 
3 181 PRO n 
3 182 PHE n 
3 183 ILE n 
3 184 SER n 
3 185 ILE n 
3 186 GLY n 
3 187 ASN n 
3 188 ALA n 
3 189 TYR n 
3 190 SER n 
3 191 CYS n 
3 192 PHE n 
3 193 TYR n 
3 194 ASP n 
3 195 GLY n 
3 196 TRP n 
3 197 THR n 
3 198 GLN n 
3 199 PHE n 
3 200 SER n 
3 201 ARG n 
3 202 ASN n 
3 203 GLY n 
3 204 VAL n 
3 205 TYR n 
3 206 GLY n 
3 207 ILE n 
3 208 ASN n 
3 209 THR n 
3 210 LEU n 
3 211 ASN n 
3 212 ASN n 
3 213 MET n 
3 214 GLY n 
3 215 THR n 
3 216 LEU n 
3 217 TYR n 
3 218 MET n 
3 219 ARG n 
3 220 HIS n 
3 221 VAL n 
3 222 ASN n 
3 223 GLU n 
3 224 ALA n 
3 225 GLY n 
3 226 GLN n 
3 227 GLY n 
3 228 PRO n 
3 229 ILE n 
3 230 LYS n 
3 231 SER n 
3 232 THR n 
3 233 VAL n 
3 234 ARG n 
3 235 ILE n 
3 236 TYR n 
3 237 PHE n 
3 238 LYS n 
3 239 PRO n 
3 240 LYS n 
3 241 HIS n 
3 242 VAL n 
3 243 LYS n 
3 244 ALA n 
3 245 TRP n 
3 246 VAL n 
3 247 PRO n 
3 248 ARG n 
3 249 PRO n 
3 250 PRO n 
3 251 ARG n 
3 252 LEU n 
3 253 CYS n 
3 254 GLN n 
3 255 TYR n 
3 256 GLU n 
3 257 LYS n 
3 258 GLN n 
3 259 LYS n 
3 260 ASN n 
3 261 VAL n 
3 262 ASN n 
3 263 PHE n 
3 264 SER n 
3 265 PRO n 
3 266 ILE n 
3 267 GLY n 
3 268 VAL n 
3 269 THR n 
3 270 THR n 
3 271 SER n 
3 272 ARG n 
3 273 THR n 
3 274 ASP n 
3 275 ILE n 
3 276 ILE n 
3 277 THR n 
3 278 THR n 
4 1   SER n 
4 2   PRO n 
4 3   SER n 
4 4   ALA n 
4 5   GLU n 
4 6   GLU n 
4 7   CYS n 
4 8   GLY n 
4 9   TYR n 
4 10  SER n 
4 11  ASP n 
4 12  ARG n 
4 13  VAL n 
4 14  ARG n 
4 15  SER n 
4 16  ILE n 
4 17  THR n 
4 18  LEU n 
4 19  GLY n 
4 20  ASN n 
4 21  SER n 
4 22  THR n 
4 23  ILE n 
4 24  THR n 
4 25  THR n 
4 26  GLN n 
4 27  GLU n 
4 28  CYS n 
4 29  ALA n 
4 30  ASN n 
4 31  VAL n 
4 32  VAL n 
4 33  VAL n 
4 34  GLY n 
4 35  TYR n 
4 36  GLY n 
4 37  VAL n 
4 38  TRP n 
4 39  PRO n 
4 40  GLU n 
4 41  TYR n 
4 42  LEU n 
4 43  LYS n 
4 44  ASP n 
4 45  ASN n 
4 46  GLU n 
4 47  ALA n 
4 48  THR n 
4 49  ALA n 
4 50  GLU n 
4 51  ASP n 
4 52  GLN n 
4 53  PRO n 
4 54  THR n 
4 55  GLN n 
4 56  PRO n 
4 57  ASP n 
4 58  VAL n 
4 59  ALA n 
4 60  THR n 
4 61  CYS n 
4 62  ARG n 
4 63  PHE n 
4 64  TYR n 
4 65  THR n 
4 66  LEU n 
4 67  GLU n 
4 68  SER n 
4 69  VAL n 
4 70  GLN n 
4 71  TRP n 
4 72  MET n 
4 73  LYS n 
4 74  ASN n 
4 75  SER n 
4 76  ALA n 
4 77  GLY n 
4 78  TRP n 
4 79  TRP n 
4 80  TRP n 
4 81  LYS n 
4 82  LEU n 
4 83  PRO n 
4 84  ASP n 
4 85  ALA n 
4 86  LEU n 
4 87  SER n 
4 88  GLN n 
4 89  MET n 
4 90  GLY n 
4 91  LEU n 
4 92  PHE n 
4 93  GLY n 
4 94  GLN n 
4 95  ASN n 
4 96  MET n 
4 97  GLN n 
4 98  TYR n 
4 99  HIS n 
4 100 TYR n 
4 101 LEU n 
4 102 GLY n 
4 103 ARG n 
4 104 THR n 
4 105 GLY n 
4 106 TYR n 
4 107 THR n 
4 108 ILE n 
4 109 HIS n 
4 110 VAL n 
4 111 GLN n 
4 112 CYS n 
4 113 ASN n 
4 114 ALA n 
4 115 SER n 
4 116 LYS n 
4 117 PHE n 
4 118 HIS n 
4 119 GLN n 
4 120 GLY n 
4 121 CYS n 
4 122 LEU n 
4 123 LEU n 
4 124 VAL n 
4 125 VAL n 
4 126 CYS n 
4 127 VAL n 
4 128 PRO n 
4 129 GLU n 
4 130 ALA n 
4 131 GLU n 
4 132 MET n 
4 133 GLY n 
4 134 CYS n 
4 135 SER n 
4 136 ASN n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 THR n 
4 141 PRO n 
4 142 GLU n 
4 143 PHE n 
4 144 SER n 
4 145 GLU n 
4 146 LEU n 
4 147 SER n 
4 148 GLY n 
4 149 GLY n 
4 150 ASP n 
4 151 SER n 
4 152 ALA n 
4 153 ARG n 
4 154 MET n 
4 155 PHE n 
4 156 THR n 
4 157 ASP n 
4 158 THR n 
4 159 GLN n 
4 160 VAL n 
4 161 GLY n 
4 162 GLU n 
4 163 SER n 
4 164 ASN n 
4 165 ALA n 
4 166 LYS n 
4 167 LYS n 
4 168 VAL n 
4 169 GLN n 
4 170 THR n 
4 171 ALA n 
4 172 VAL n 
4 173 TRP n 
4 174 ASN n 
4 175 ALA n 
4 176 GLY n 
4 177 MET n 
4 178 GLY n 
4 179 VAL n 
4 180 GLY n 
4 181 VAL n 
4 182 GLY n 
4 183 ASN n 
4 184 LEU n 
4 185 THR n 
4 186 ILE n 
4 187 PHE n 
4 188 PRO n 
4 189 HIS n 
4 190 GLN n 
4 191 TRP n 
4 192 ILE n 
4 193 ASN n 
4 194 LEU n 
4 195 ARG n 
4 196 THR n 
4 197 ASN n 
4 198 ASN n 
4 199 SER n 
4 200 ALA n 
4 201 THR n 
4 202 LEU n 
4 203 VAL n 
4 204 MET n 
4 205 PRO n 
4 206 TYR n 
4 207 ILE n 
4 208 ASN n 
4 209 SER n 
4 210 VAL n 
4 211 PRO n 
4 212 MET n 
4 213 ASP n 
4 214 ASN n 
4 215 MET n 
4 216 PHE n 
4 217 ARG n 
4 218 HIS n 
4 219 ASN n 
4 220 ASN n 
4 221 LEU n 
4 222 THR n 
4 223 LEU n 
4 224 MET n 
4 225 ILE n 
4 226 ILE n 
4 227 PRO n 
4 228 PHE n 
4 229 VAL n 
4 230 PRO n 
4 231 LEU n 
4 232 ASN n 
4 233 TYR n 
4 234 SER n 
4 235 GLU n 
4 236 GLY n 
4 237 SER n 
4 238 SER n 
4 239 PRO n 
4 240 TYR n 
4 241 VAL n 
4 242 PRO n 
4 243 ILE n 
4 244 THR n 
4 245 VAL n 
4 246 THR n 
4 247 ILE n 
4 248 ALA n 
4 249 PRO n 
4 250 MET n 
4 251 CYS n 
4 252 ALA n 
4 253 GLU n 
4 254 TYR n 
4 255 ASN n 
4 256 GLY n 
4 257 LEU n 
4 258 ARG n 
4 259 LEU n 
4 260 ALA n 
4 261 SER n 
4 262 ASN n 
4 263 GLN n 
5 1   GLY n 
5 2   LEU n 
5 3   PRO n 
5 4   VAL n 
5 5   MET n 
5 6   THR n 
5 7   THR n 
5 8   PRO n 
5 9   GLY n 
5 10  SER n 
5 11  THR n 
5 12  GLN n 
5 13  PHE n 
5 14  LEU n 
5 15  THR n 
5 16  SER n 
5 17  ASP n 
5 18  ASP n 
5 19  PHE n 
5 20  GLN n 
5 21  SER n 
5 22  PRO n 
5 23  SER n 
5 24  ALA n 
5 25  MET n 
5 26  PRO n 
5 27  GLN n 
5 28  PHE n 
5 29  ASP n 
5 30  VAL n 
5 31  THR n 
5 32  PRO n 
5 33  GLU n 
5 34  MET n 
5 35  GLN n 
5 36  ILE n 
5 37  PRO n 
5 38  GLY n 
5 39  ARG n 
5 40  VAL n 
5 41  ASN n 
5 42  ASN n 
5 43  LEU n 
5 44  MET n 
5 45  GLU n 
5 46  ILE n 
5 47  ALA n 
5 48  GLU n 
5 49  VAL n 
5 50  ASP n 
5 51  SER n 
5 52  VAL n 
5 53  VAL n 
5 54  PRO n 
5 55  VAL n 
5 56  ASN n 
5 57  ASN n 
5 58  THR n 
5 59  GLU n 
5 60  ASP n 
5 61  ASN n 
5 62  VAL n 
5 63  SER n 
5 64  SER n 
5 65  LEU n 
5 66  LYS n 
5 67  ALA n 
5 68  TYR n 
5 69  GLN n 
5 70  ILE n 
5 71  PRO n 
5 72  VAL n 
5 73  GLN n 
5 74  SER n 
5 75  ASN n 
5 76  SER n 
5 77  ASP n 
5 78  ASN n 
5 79  GLY n 
5 80  LYS n 
5 81  GLN n 
5 82  VAL n 
5 83  PHE n 
5 84  GLY n 
5 85  PHE n 
5 86  PRO n 
5 87  LEU n 
5 88  GLN n 
5 89  PRO n 
5 90  GLY n 
5 91  ALA n 
5 92  ASN n 
5 93  ASN n 
5 94  VAL n 
5 95  LEU n 
5 96  ASN n 
5 97  ARG n 
5 98  THR n 
5 99  LEU n 
5 100 LEU n 
5 101 GLY n 
5 102 GLU n 
5 103 ILE n 
5 104 LEU n 
5 105 ASN n 
5 106 TYR n 
5 107 TYR n 
5 108 THR n 
5 109 HIS n 
5 110 TRP n 
5 111 SER n 
5 112 GLY n 
5 113 SER n 
5 114 ILE n 
5 115 LYS n 
5 116 LEU n 
5 117 THR n 
5 118 PHE n 
5 119 MET n 
5 120 PHE n 
5 121 CYS n 
5 122 GLY n 
5 123 SER n 
5 124 ALA n 
5 125 MET n 
5 126 ALA n 
5 127 THR n 
5 128 GLY n 
5 129 LYS n 
5 130 PHE n 
5 131 LEU n 
5 132 LEU n 
5 133 ALA n 
5 134 TYR n 
5 135 SER n 
5 136 PRO n 
5 137 PRO n 
5 138 GLY n 
5 139 ALA n 
5 140 GLY n 
5 141 VAL n 
5 142 PRO n 
5 143 LYS n 
5 144 ASN n 
5 145 ARG n 
5 146 LYS n 
5 147 ASP n 
5 148 ALA n 
5 149 MET n 
5 150 LEU n 
5 151 GLY n 
5 152 THR n 
5 153 HIS n 
5 154 VAL n 
5 155 ILE n 
5 156 TRP n 
5 157 ASP n 
5 158 VAL n 
5 159 GLY n 
5 160 LEU n 
5 161 GLN n 
5 162 SER n 
5 163 SER n 
5 164 CYS n 
5 165 VAL n 
5 166 LEU n 
5 167 CYS n 
5 168 VAL n 
5 169 PRO n 
5 170 TRP n 
5 171 ILE n 
5 172 SER n 
5 173 GLN n 
5 174 THR n 
5 175 HIS n 
5 176 TYR n 
5 177 ARG n 
5 178 TYR n 
5 179 VAL n 
5 180 VAL n 
5 181 GLU n 
5 182 ASP n 
5 183 GLU n 
5 184 TYR n 
5 185 THR n 
5 186 ALA n 
5 187 ALA n 
5 188 GLY n 
5 189 TYR n 
5 190 VAL n 
5 191 THR n 
5 192 CYS n 
5 193 TRP n 
5 194 TYR n 
5 195 GLN n 
5 196 THR n 
5 197 ASN n 
5 198 ILE n 
5 199 VAL n 
5 200 VAL n 
5 201 PRO n 
5 202 ALA n 
5 203 ASP n 
5 204 VAL n 
5 205 GLN n 
5 206 SER n 
5 207 SER n 
5 208 CYS n 
5 209 ASP n 
5 210 ILE n 
5 211 LEU n 
5 212 CYS n 
5 213 PHE n 
5 214 VAL n 
5 215 SER n 
5 216 ALA n 
5 217 CYS n 
5 218 ASN n 
5 219 ASP n 
5 220 PHE n 
5 221 SER n 
5 222 VAL n 
5 223 ARG n 
5 224 MET n 
5 225 LEU n 
5 226 LYS n 
5 227 ASP n 
5 228 THR n 
5 229 PRO n 
5 230 PHE n 
5 231 ILE n 
5 232 ARG n 
5 233 GLN n 
5 234 ASP n 
5 235 THR n 
5 236 PHE n 
5 237 TYR n 
5 238 GLN n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 124 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 108 ? 'Mus musculus'      10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 1 278 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 1 263 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 1 238 ? 'Coxsackievirus B1' 12071 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7X4K             7X4K       ? 1 ? 1   
2 PDB 7X4K             7X4K       ? 2 ? 1   
3 UNP W8GTF7_9ENTO     W8GTF7     ? 3 
;GPVEESVDRAVARVADTISSRPTNSESIPALTAAETGHTSQVVPSDTMQTRHVKNYHSRSESSIENFLCRSACVYYATYT
NNSEKGFAEWVINTRQVAQLRRKLELFTYLRFDLELTFVITSAQQPSTASSVDAPVQTHQIMYVPPGGPVPTKVKDYAWQ
TSTNPSVFWTEGNAPPRMSIPFISIGNAYSCFYDGWTQFSRNGVYGINTLNNMGTLYMRHVNEAGQGPIKSTVRIYFKPK
HVKAWVPRPPRLCQYEKQKNVNFSPIGVTTSRTDIITT
;
1   
4 UNP A0A7T7KAA0_9ENTO A0A7T7KAA0 ? 4 
;SPSAEECGYSDRVRSITLGNSTITTQECANVVVGYGVWPEYLKDNEATAEDQPTQPDVATCRFYTLESVQWMKNSAGWWW
KLPDALSQMGLFGQNMQYHYLGRTGYTIHVQCNASKFHQGCLLVVCVPEAEMGCSNLNNTPEFSELSGGDSARMFTDTQV
GESNAKKVQTAVWNAGMGVGVGNLTIFPHQWINLRTNNSATLVMPYINSVPMDNMFRHNNLTLMIIPFVPLNYSEGSSPY
VPITVTIAPMCAEYNGLRLASNQ
;
70  
5 UNP L7UV52_9ENTO     L7UV52     ? 5 
;GLPVMTTPGSTQFLTSDDFQSPSAMPQFDVTPEMQIPGRVNNLMEIAEVDSVVPVNNTEDNVSSLKAYQIPVQSNSDNGK
QVFGFPLQPGANNVLNRTLLGEILNYYTHWSGSIKLTFMFCGSAMATGKFLLAYSPPGAGVPKNRKDAMLGTHVIWDVGL
QSSCVLCVPWISQTHYRYVVEDEYTAAGYVTCWYQTNIVVPADVQSSCDILCFVSACNDFSVRMLKDTPFIRQDTFYQ
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7X4K H 1 ? 124 ? 7X4K       1   ? 124 ? 1 124 
2 2 7X4K L 1 ? 108 ? 7X4K       1   ? 108 ? 1 108 
3 3 7X4K A 1 ? 278 ? W8GTF7     1   ? 278 ? 1 278 
4 4 7X4K B 1 ? 263 ? A0A7T7KAA0 70  ? 332 ? 1 263 
5 5 7X4K C 1 ? 238 ? L7UV52     333 ? 570 ? 1 238 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             7X4K 
_struct_ref_seq_dif.mon_id                       LYS 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      84 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   W8GTF7 
_struct_ref_seq_dif.db_mon_id                    GLU 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          84 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            84 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7X4K 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     7X4K 
_struct.title                        
;Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (classified from CVB1 mature virion in complex with 8A10 and 9A3)
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        7X4K 
_struct_keywords.text            'Coxsackievirus B1, Neutralizing antibody, Cryo-EM, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 28  ? TYR A 32  ? THR H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2  AA2 ASN A 53  ? GLY A 57  ? ASN H 53  GLY H 57  5 ? 5 
HELX_P HELX_P3  AA3 ARG C 59  ? SER C 63  ? ARG A 59  SER A 63  5 ? 5 
HELX_P HELX_P4  AA4 ILE C 64  ? CYS C 69  ? ILE A 64  CYS A 69  1 ? 6 
HELX_P HELX_P5  AA5 VAL C 97  ? GLU C 105 ? VAL A 97  GLU A 105 1 ? 9 
HELX_P HELX_P6  AA6 ASP C 156 ? THR C 161 ? ASP A 156 THR A 161 5 ? 6 
HELX_P HELX_P7  AA7 LEU D 82  ? LEU D 86  ? LEU B 82  LEU B 86  1 ? 5 
HELX_P HELX_P8  AA8 LEU D 91  ? TYR D 98  ? LEU B 91  TYR B 98  1 ? 8 
HELX_P HELX_P9  AA9 GLU D 142 ? SER D 147 ? GLU B 142 SER B 147 1 ? 6 
HELX_P HELX_P10 AB1 ALA D 171 ? ALA D 175 ? ALA B 171 ALA B 175 5 ? 5 
HELX_P HELX_P11 AB2 VAL D 181 ? PHE D 187 ? VAL B 181 PHE B 187 5 ? 7 
HELX_P HELX_P12 AB3 GLU E 45  ? VAL E 49  ? GLU C 45  VAL C 49  5 ? 5 
HELX_P HELX_P13 AB4 SER E 64  ? TYR E 68  ? SER C 64  TYR C 68  5 ? 5 
HELX_P HELX_P14 AB5 THR E 98  ? LEU E 104 ? THR C 98  LEU C 104 1 ? 7 
HELX_P HELX_P15 AB6 ASN E 144 ? GLY E 151 ? ASN C 144 GLY C 151 1 ? 8 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22 SG ? ? ? 1_555 A CYS 98 SG ? ? H CYS 22 H CYS 98 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 89 SG ? ? L CYS 23 L CYS 89 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 7  B . ? SER 7  L PRO 8  B ? PRO 8  L 1 -8.14 
2 TYR 95 B . ? TYR 95 L PRO 96 B ? PRO 96 L 1 7.87  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 7 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 9 ? 
AB3 ? 5 ? 
AB4 ? 6 ? 
AB5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 6 ? anti-parallel 
AA8 2 4 ? anti-parallel 
AA8 2 5 ? anti-parallel 
AA8 2 6 ? anti-parallel 
AA8 3 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 6 ? parallel      
AB2 2 9 ? anti-parallel 
AB2 3 8 ? anti-parallel 
AB2 4 8 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB2 5 7 ? anti-parallel 
AB2 5 8 ? anti-parallel 
AB2 5 9 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB4 1 5 ? anti-parallel 
AB4 2 5 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 3 5 ? anti-parallel 
AB4 3 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 5   ? SER A 7   ? VAL H 5   SER H 7   
AA1 2 SER A 17  ? ALA A 23  ? SER H 17  ALA H 23  
AA1 3 ILE A 80  ? ASN A 86  ? ILE H 80  ASN H 86  
AA1 4 PHE A 70  ? ARG A 74  ? PHE H 70  ARG H 74  
AA2 1 TYR A 33  ? ASN A 35  ? TYR H 33  ASN H 35  
AA2 2 ALA A 99  ? SER A 101 ? ALA H 99  SER H 101 
AA2 3 TYR A 114 ? TRP A 115 ? TYR H 114 TRP H 115 
AA3 1 GLU A 46  ? TRP A 47  ? GLU H 46  TRP H 47  
AA3 2 VAL A 37  ? GLN A 39  ? VAL H 37  GLN H 39  
AA3 3 ALA A 94  ? TYR A 96  ? ALA H 94  TYR H 96  
AA3 4 THR A 119 ? VAL A 121 ? THR H 119 VAL H 121 
AA4 1 GLY A 49  ? LEU A 51  ? GLY H 49  LEU H 51  
AA4 2 THR A 60  ? TYR A 62  ? THR H 60  TYR H 62  
AA5 1 LEU B 4   ? SER B 7   ? LEU L 4   SER L 7   
AA5 2 VAL B 19  ? ALA B 25  ? VAL L 19  ALA L 25  
AA5 3 SER B 71  ? ILE B 76  ? SER L 71  ILE L 76  
AA5 4 SER B 64  ? SER B 68  ? SER L 64  SER L 68  
AA6 1 ILE B 10  ? ALA B 13  ? ILE L 10  ALA L 13  
AA6 2 LYS B 104 ? LEU B 107 ? LYS L 104 LEU L 107 
AA7 1 ASN B 54  ? LEU B 55  ? ASN L 54  LEU L 55  
AA7 2 LYS B 46  ? TYR B 50  ? LYS L 46  TYR L 50  
AA7 3 HIS B 35  ? GLN B 39  ? HIS L 35  GLN L 39  
AA7 4 THR B 86  ? GLN B 90  ? THR L 86  GLN L 90  
AA8 1 TYR C 75  ? THR C 80  ? TYR A 75  THR A 80  
AA8 2 PHE C 107 ? PHE C 118 ? PHE A 107 PHE A 118 
AA8 3 THR C 121 ? GLN C 124 ? THR A 121 GLN A 124 
AA8 4 MET C 178 ? ILE C 180 ? MET A 178 ILE A 180 
AA8 5 TYR C 189 ? SER C 190 ? TYR A 189 SER A 190 
AA8 6 ILE C 229 ? PRO C 247 ? ILE A 229 PRO A 247 
AA8 7 ARG E 39  ? VAL E 40  ? ARG C 39  VAL C 40  
AA9 1 ALA C 88  ? VAL C 91  ? ALA A 88  VAL A 91  
AA9 2 THR C 215 ? HIS C 220 ? THR A 215 HIS A 220 
AA9 3 THR C 138 ? VAL C 144 ? THR A 138 VAL A 144 
AA9 4 SER C 166 ? THR C 170 ? SER A 166 THR A 170 
AB1 1 ILE D 16  ? LEU D 18  ? ILE B 16  LEU B 18  
AB1 2 SER D 21  ? ILE D 23  ? SER B 21  ILE B 23  
AB2 1 VAL D 32  ? VAL D 33  ? VAL B 32  VAL B 33  
AB2 2 PRO D 53  ? THR D 54  ? PRO B 53  THR B 54  
AB2 3 TYR D 64  ? THR D 65  ? TYR B 64  THR B 65  
AB2 4 VAL D 69  ? TRP D 71  ? VAL B 69  TRP B 71  
AB2 5 LEU D 101 ? CYS D 112 ? LEU B 101 CYS B 112 
AB2 6 SER D 199 ? MET D 204 ? SER B 199 MET B 204 
AB2 7 ASP D 213 ? ASN D 214 ? ASP B 213 ASN B 214 
AB2 8 VAL D 241 ? ILE D 247 ? VAL B 241 ILE B 247 
AB2 9 MET D 250 ? ASN D 255 ? MET B 250 ASN B 255 
AB3 1 ARG D 153 ? MET D 154 ? ARG B 153 MET B 154 
AB3 2 TRP D 78  ? LYS D 81  ? TRP B 78  LYS B 81  
AB3 3 LEU D 221 ? PRO D 227 ? LEU B 221 PRO B 227 
AB3 4 CYS D 121 ? PRO D 128 ? CYS B 121 PRO B 128 
AB3 5 HIS D 189 ? ASN D 193 ? HIS B 189 ASN B 193 
AB4 1 SER E 51  ? VAL E 52  ? SER C 51  VAL C 52  
AB4 2 ILE E 70  ? VAL E 72  ? ILE C 70  VAL C 72  
AB4 3 TYR E 107 ? CYS E 121 ? TYR C 107 CYS C 121 
AB4 4 VAL E 165 ? ILE E 171 ? VAL C 165 ILE C 171 
AB4 5 CYS E 208 ? VAL E 214 ? CYS C 208 VAL C 214 
AB4 6 VAL E 222 ? LEU E 225 ? VAL C 222 LEU C 225 
AB5 1 GLN E 81  ? PHE E 83  ? GLN C 81  PHE C 83  
AB5 2 CYS E 192 ? TYR E 194 ? CYS C 192 TYR C 194 
AB5 3 LYS E 129 ? TYR E 134 ? LYS C 129 TYR C 134 
AB5 4 THR E 152 ? ASP E 157 ? THR C 152 ASP C 157 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 5   ? N VAL H 5   O ALA A 23  ? O ALA H 23  
AA1 2 3 N LEU A 18  ? N LEU H 18  O MET A 85  ? O MET H 85  
AA1 3 4 O GLN A 84  ? O GLN H 84  N THR A 71  ? N THR H 71  
AA2 1 2 N ASN A 35  ? N ASN H 35  O ALA A 99  ? O ALA H 99  
AA2 2 3 N ARG A 100 ? N ARG H 100 O TYR A 114 ? O TYR H 114 
AA3 1 2 O GLU A 46  ? O GLU H 46  N ARG A 38  ? N ARG H 38  
AA3 2 3 N GLN A 39  ? N GLN H 39  O THR A 95  ? O THR H 95  
AA3 3 4 N TYR A 96  ? N TYR H 96  O THR A 119 ? O THR H 119 
AA4 1 2 N PHE A 50  ? N PHE H 50  O GLU A 61  ? O GLU H 61  
AA5 1 2 N THR B 5   ? N THR L 5   O ARG B 24  ? O ARG L 24  
AA5 2 3 N CYS B 23  ? N CYS L 23  O TYR B 72  ? O TYR L 72  
AA5 3 4 O THR B 75  ? O THR L 75  N SER B 64  ? N SER L 64  
AA6 1 2 N ALA B 13  ? N ALA L 13  O GLU B 106 ? O GLU L 106 
AA7 1 2 O ASN B 54  ? O ASN L 54  N TYR B 50  ? N TYR L 50  
AA7 2 3 O ILE B 49  ? O ILE L 49  N TRP B 36  ? N TRP L 36  
AA7 3 4 N GLN B 39  ? N GLN L 39  O THR B 86  ? O THR L 86  
AA8 1 6 N TYR C 79  ? N TYR A 79  O SER C 231 ? O SER A 231 
AA8 2 4 N LEU C 116 ? N LEU A 116 O MET C 178 ? O MET A 178 
AA8 2 5 N LEU C 110 ? N LEU A 110 O TYR C 189 ? O TYR A 189 
AA8 2 6 N THR C 117 ? N THR A 117 O TYR C 236 ? O TYR A 236 
AA8 3 6 N THR C 121 ? N THR A 121 O THR C 232 ? O THR A 232 
AA8 6 7 N ALA C 244 ? N ALA A 244 O VAL E 40  ? O VAL C 40  
AA9 1 2 N TRP C 90  ? N TRP A 90  O LEU C 216 ? O LEU A 216 
AA9 2 3 O TYR C 217 ? O TYR A 217 N MET C 142 ? N MET A 142 
AA9 3 4 N HIS C 139 ? N HIS A 139 O TRP C 169 ? O TRP A 169 
AB1 1 2 N LEU D 18  ? N LEU B 18  O SER D 21  ? O SER B 21  
AB2 1 6 N VAL D 32  ? N VAL B 32  O THR D 201 ? O THR B 201 
AB2 2 9 N THR D 54  ? N THR B 54  O TYR D 254 ? O TYR B 254 
AB2 3 8 N TYR D 64  ? N TYR B 64  O ILE D 247 ? O ILE B 247 
AB2 4 8 N VAL D 69  ? N VAL B 69  O ILE D 243 ? O ILE B 243 
AB2 5 6 N VAL D 110 ? N VAL B 110 O ALA D 200 ? O ALA B 200 
AB2 5 7 N GLY D 102 ? N GLY B 102 O ASP D 213 ? O ASP B 213 
AB2 5 8 N HIS D 109 ? N HIS B 109 O THR D 246 ? O THR B 246 
AB2 5 9 N GLY D 105 ? N GLY B 105 O MET D 250 ? O MET B 250 
AB3 1 2 O ARG D 153 ? O ARG B 153 N TRP D 79  ? N TRP B 79  
AB3 2 3 N TRP D 80  ? N TRP B 80  O LEU D 223 ? O LEU B 223 
AB3 3 4 O MET D 224 ? O MET B 224 N VAL D 125 ? N VAL B 125 
AB3 4 5 N LEU D 122 ? N LEU B 122 O ILE D 192 ? O ILE B 192 
AB4 1 5 N SER E 51  ? N SER C 51  O VAL E 214 ? O VAL C 214 
AB4 2 5 N VAL E 72  ? N VAL C 72  O CYS E 208 ? O CYS C 208 
AB4 3 4 N GLY E 112 ? N GLY C 112 O TRP E 170 ? O TRP C 170 
AB4 3 5 N THR E 117 ? N THR C 117 O PHE E 213 ? O PHE C 213 
AB4 3 6 N HIS E 109 ? N HIS C 109 O ARG E 223 ? O ARG C 223 
AB5 1 2 N VAL E 82  ? N VAL C 82  O CYS E 192 ? O CYS C 192 
AB5 2 3 O TRP E 193 ? O TRP C 193 N LEU E 131 ? N LEU C 131 
AB5 3 4 N PHE E 130 ? N PHE C 130 O TRP E 156 ? O TRP C 156 
# 
_atom_sites.entry_id                    7X4K 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLU A 1 1   ? 325.302 365.010 478.857 1.00 185.03 ? 1   GLU H N   1 
ATOM 2    C CA  . GLU A 1 1   ? 326.517 364.856 479.645 1.00 185.03 ? 1   GLU H CA  1 
ATOM 3    C C   . GLU A 1 1   ? 326.592 363.463 480.238 1.00 185.03 ? 1   GLU H C   1 
ATOM 4    O O   . GLU A 1 1   ? 325.626 362.977 480.819 1.00 185.03 ? 1   GLU H O   1 
ATOM 5    C CB  . GLU A 1 1   ? 326.579 365.913 480.754 1.00 185.03 ? 1   GLU H CB  1 
ATOM 6    C CG  . GLU A 1 1   ? 327.533 365.607 481.911 1.00 185.03 ? 1   GLU H CG  1 
ATOM 7    C CD  . GLU A 1 1   ? 329.004 365.823 481.578 1.00 185.03 ? 1   GLU H CD  1 
ATOM 8    O OE1 . GLU A 1 1   ? 329.842 365.597 482.473 1.00 185.03 ? 1   GLU H OE1 1 
ATOM 9    O OE2 . GLU A 1 1   ? 329.334 366.242 480.450 1.00 185.03 ? 1   GLU H OE2 1 
ATOM 10   N N   . VAL A 1 2   ? 327.746 362.825 480.084 1.00 184.15 ? 2   VAL H N   1 
ATOM 11   C CA  . VAL A 1 2   ? 327.966 361.479 480.596 1.00 184.15 ? 2   VAL H CA  1 
ATOM 12   C C   . VAL A 1 2   ? 328.056 361.534 482.119 1.00 184.15 ? 2   VAL H C   1 
ATOM 13   O O   . VAL A 1 2   ? 328.512 362.529 482.695 1.00 184.15 ? 2   VAL H O   1 
ATOM 14   C CB  . VAL A 1 2   ? 329.217 360.846 479.965 1.00 184.15 ? 2   VAL H CB  1 
ATOM 15   C CG1 . VAL A 1 2   ? 329.102 360.880 478.456 1.00 184.15 ? 2   VAL H CG1 1 
ATOM 16   C CG2 . VAL A 1 2   ? 330.471 361.588 480.364 1.00 184.15 ? 2   VAL H CG2 1 
ATOM 17   N N   . LYS A 1 3   ? 327.542 360.497 482.772 1.00 183.44 ? 3   LYS H N   1 
ATOM 18   C CA  . LYS A 1 3   ? 327.557 360.373 484.226 1.00 183.44 ? 3   LYS H CA  1 
ATOM 19   C C   . LYS A 1 3   ? 327.497 358.890 484.547 1.00 183.44 ? 3   LYS H C   1 
ATOM 20   O O   . LYS A 1 3   ? 326.419 358.290 484.516 1.00 183.44 ? 3   LYS H O   1 
ATOM 21   C CB  . LYS A 1 3   ? 326.380 361.110 484.865 1.00 183.44 ? 3   LYS H CB  1 
ATOM 22   C CG  . LYS A 1 3   ? 326.697 362.501 485.388 1.00 183.44 ? 3   LYS H CG  1 
ATOM 23   C CD  . LYS A 1 3   ? 327.815 362.474 486.413 1.00 183.44 ? 3   LYS H CD  1 
ATOM 24   C CE  . LYS A 1 3   ? 327.927 363.809 487.128 1.00 183.44 ? 3   LYS H CE  1 
ATOM 25   N NZ  . LYS A 1 3   ? 326.686 364.128 487.883 1.00 183.44 ? 3   LYS H NZ  1 
ATOM 26   N N   . LEU A 1 4   ? 328.641 358.301 484.864 1.00 184.66 ? 4   LEU H N   1 
ATOM 27   C CA  . LEU A 1 4   ? 328.739 356.866 485.088 1.00 184.66 ? 4   LEU H CA  1 
ATOM 28   C C   . LEU A 1 4   ? 328.854 356.613 486.582 1.00 184.66 ? 4   LEU H C   1 
ATOM 29   O O   . LEU A 1 4   ? 329.853 356.991 487.205 1.00 184.66 ? 4   LEU H O   1 
ATOM 30   C CB  . LEU A 1 4   ? 329.936 356.281 484.340 1.00 184.66 ? 4   LEU H CB  1 
ATOM 31   C CG  . LEU A 1 4   ? 329.797 356.294 482.821 1.00 184.66 ? 4   LEU H CG  1 
ATOM 32   C CD1 . LEU A 1 4   ? 331.143 356.132 482.155 1.00 184.66 ? 4   LEU H CD1 1 
ATOM 33   C CD2 . LEU A 1 4   ? 328.871 355.191 482.395 1.00 184.66 ? 4   LEU H CD2 1 
ATOM 34   N N   . VAL A 1 5   ? 327.838 355.977 487.153 1.00 192.61 ? 5   VAL H N   1 
ATOM 35   C CA  . VAL A 1 5   ? 327.823 355.665 488.574 1.00 192.61 ? 5   VAL H CA  1 
ATOM 36   C C   . VAL A 1 5   ? 327.986 354.159 488.733 1.00 192.61 ? 5   VAL H C   1 
ATOM 37   O O   . VAL A 1 5   ? 327.466 353.364 487.944 1.00 192.61 ? 5   VAL H O   1 
ATOM 38   C CB  . VAL A 1 5   ? 326.541 356.205 489.263 1.00 192.61 ? 5   VAL H CB  1 
ATOM 39   C CG1 . VAL A 1 5   ? 325.270 355.570 488.703 1.00 192.61 ? 5   VAL H CG1 1 
ATOM 40   C CG2 . VAL A 1 5   ? 326.615 356.057 490.779 1.00 192.61 ? 5   VAL H CG2 1 
ATOM 41   N N   . GLU A 1 6   ? 328.786 353.774 489.725 1.00 196.47 ? 6   GLU H N   1 
ATOM 42   C CA  . GLU A 1 6   ? 329.133 352.382 489.959 1.00 196.47 ? 6   GLU H CA  1 
ATOM 43   C C   . GLU A 1 6   ? 328.947 352.054 491.431 1.00 196.47 ? 6   GLU H C   1 
ATOM 44   O O   . GLU A 1 6   ? 329.233 352.872 492.307 1.00 196.47 ? 6   GLU H O   1 
ATOM 45   C CB  . GLU A 1 6   ? 330.575 352.086 489.519 1.00 196.47 ? 6   GLU H CB  1 
ATOM 46   C CG  . GLU A 1 6   ? 331.611 353.080 490.032 1.00 196.47 ? 6   GLU H CG  1 
ATOM 47   C CD  . GLU A 1 6   ? 331.861 354.220 489.060 1.00 196.47 ? 6   GLU H CD  1 
ATOM 48   O OE1 . GLU A 1 6   ? 331.053 354.400 488.125 1.00 196.47 ? 6   GLU H OE1 1 
ATOM 49   O OE2 . GLU A 1 6   ? 332.862 354.941 489.228 1.00 196.47 ? 6   GLU H OE2 1 
ATOM 50   N N   . SER A 1 7   ? 328.455 350.848 491.694 1.00 198.37 ? 7   SER H N   1 
ATOM 51   C CA  . SER A 1 7   ? 328.182 350.429 493.062 1.00 198.37 ? 7   SER H CA  1 
ATOM 52   C C   . SER A 1 7   ? 328.559 348.964 493.210 1.00 198.37 ? 7   SER H C   1 
ATOM 53   O O   . SER A 1 7   ? 328.807 348.262 492.227 1.00 198.37 ? 7   SER H O   1 
ATOM 54   C CB  . SER A 1 7   ? 326.713 350.656 493.434 1.00 198.37 ? 7   SER H CB  1 
ATOM 55   O OG  . SER A 1 7   ? 326.264 351.935 493.021 1.00 198.37 ? 7   SER H OG  1 
ATOM 56   N N   . GLY A 1 8   ? 328.597 348.511 494.459 1.00 197.24 ? 8   GLY H N   1 
ATOM 57   C CA  . GLY A 1 8   ? 328.891 347.122 494.769 1.00 197.24 ? 8   GLY H CA  1 
ATOM 58   C C   . GLY A 1 8   ? 330.141 346.896 495.595 1.00 197.24 ? 8   GLY H C   1 
ATOM 59   O O   . GLY A 1 8   ? 330.453 345.736 495.900 1.00 197.24 ? 8   GLY H O   1 
ATOM 60   N N   . GLY A 1 9   ? 330.877 347.934 495.979 1.00 195.57 ? 9   GLY H N   1 
ATOM 61   C CA  . GLY A 1 9   ? 332.101 347.737 496.725 1.00 195.57 ? 9   GLY H CA  1 
ATOM 62   C C   . GLY A 1 9   ? 331.859 347.512 498.204 1.00 195.57 ? 9   GLY H C   1 
ATOM 63   O O   . GLY A 1 9   ? 330.910 348.015 498.806 1.00 195.57 ? 9   GLY H O   1 
ATOM 64   N N   . GLY A 1 10  ? 332.753 346.735 498.801 1.00 197.63 ? 10  GLY H N   1 
ATOM 65   C CA  . GLY A 1 10  ? 332.648 346.430 500.215 1.00 197.63 ? 10  GLY H CA  1 
ATOM 66   C C   . GLY A 1 10  ? 333.522 345.240 500.577 1.00 197.63 ? 10  GLY H C   1 
ATOM 67   O O   . GLY A 1 10  ? 334.422 344.864 499.830 1.00 197.63 ? 10  GLY H O   1 
ATOM 68   N N   . LEU A 1 11  ? 333.223 344.664 501.737 1.00 199.48 ? 11  LEU H N   1 
ATOM 69   C CA  . LEU A 1 11  ? 334.001 343.564 502.284 1.00 199.48 ? 11  LEU H CA  1 
ATOM 70   C C   . LEU A 1 11  ? 333.684 342.266 501.554 1.00 199.48 ? 11  LEU H C   1 
ATOM 71   O O   . LEU A 1 11  ? 332.536 342.021 501.171 1.00 199.48 ? 11  LEU H O   1 
ATOM 72   C CB  . LEU A 1 11  ? 333.713 343.395 503.778 1.00 199.48 ? 11  LEU H CB  1 
ATOM 73   C CG  . LEU A 1 11  ? 334.161 344.479 504.764 1.00 199.48 ? 11  LEU H CG  1 
ATOM 74   C CD1 . LEU A 1 11  ? 334.285 343.896 506.160 1.00 199.48 ? 11  LEU H CD1 1 
ATOM 75   C CD2 . LEU A 1 11  ? 335.469 345.125 504.353 1.00 199.48 ? 11  LEU H CD2 1 
ATOM 76   N N   . VAL A 1 12  ? 334.709 341.436 501.372 1.00 200.75 ? 12  VAL H N   1 
ATOM 77   C CA  . VAL A 1 12  ? 334.544 340.099 500.810 1.00 200.75 ? 12  VAL H CA  1 
ATOM 78   C C   . VAL A 1 12  ? 335.714 339.245 501.291 1.00 200.75 ? 12  VAL H C   1 
ATOM 79   O O   . VAL A 1 12  ? 336.839 339.732 501.439 1.00 200.75 ? 12  VAL H O   1 
ATOM 80   C CB  . VAL A 1 12  ? 334.425 340.149 499.263 1.00 200.75 ? 12  VAL H CB  1 
ATOM 81   C CG1 . VAL A 1 12  ? 335.645 340.798 498.617 1.00 200.75 ? 12  VAL H CG1 1 
ATOM 82   C CG2 . VAL A 1 12  ? 334.123 338.771 498.662 1.00 200.75 ? 12  VAL H CG2 1 
ATOM 83   N N   . GLN A 1 13  ? 335.423 337.980 501.592 1.00 202.03 ? 13  GLN H N   1 
ATOM 84   C CA  . GLN A 1 13  ? 336.451 337.039 502.009 1.00 202.03 ? 13  GLN H CA  1 
ATOM 85   C C   . GLN A 1 13  ? 337.201 336.497 500.790 1.00 202.03 ? 13  GLN H C   1 
ATOM 86   O O   . GLN A 1 13  ? 336.674 336.509 499.674 1.00 202.03 ? 13  GLN H O   1 
ATOM 87   C CB  . GLN A 1 13  ? 335.837 335.886 502.811 1.00 202.03 ? 13  GLN H CB  1 
ATOM 88   C CG  . GLN A 1 13  ? 335.095 334.821 502.006 1.00 202.03 ? 13  GLN H CG  1 
ATOM 89   C CD  . GLN A 1 13  ? 333.786 335.314 501.428 1.00 202.03 ? 13  GLN H CD  1 
ATOM 90   O OE1 . GLN A 1 13  ? 332.961 335.890 502.135 1.00 202.03 ? 13  GLN H OE1 1 
ATOM 91   N NE2 . GLN A 1 13  ? 333.592 335.099 500.133 1.00 202.03 ? 13  GLN H NE2 1 
ATOM 92   N N   . PRO A 1 14  ? 338.452 336.069 500.967 1.00 200.47 ? 14  PRO H N   1 
ATOM 93   C CA  . PRO A 1 14  ? 339.172 335.435 499.856 1.00 200.47 ? 14  PRO H CA  1 
ATOM 94   C C   . PRO A 1 14  ? 338.583 334.076 499.504 1.00 200.47 ? 14  PRO H C   1 
ATOM 95   O O   . PRO A 1 14  ? 338.184 333.304 500.378 1.00 200.47 ? 14  PRO H O   1 
ATOM 96   C CB  . PRO A 1 14  ? 340.602 335.302 500.389 1.00 200.47 ? 14  PRO H CB  1 
ATOM 97   C CG  . PRO A 1 14  ? 340.709 336.329 501.450 1.00 200.47 ? 14  PRO H CG  1 
ATOM 98   C CD  . PRO A 1 14  ? 339.356 336.403 502.080 1.00 200.47 ? 14  PRO H CD  1 
ATOM 99   N N   . GLY A 1 15  ? 338.540 333.790 498.203 1.00 198.11 ? 15  GLY H N   1 
ATOM 100  C CA  . GLY A 1 15  ? 337.985 332.557 497.689 1.00 198.11 ? 15  GLY H CA  1 
ATOM 101  C C   . GLY A 1 15  ? 336.546 332.636 497.225 1.00 198.11 ? 15  GLY H C   1 
ATOM 102  O O   . GLY A 1 15  ? 336.024 331.638 496.714 1.00 198.11 ? 15  GLY H O   1 
ATOM 103  N N   . GLY A 1 16  ? 335.892 333.787 497.370 1.00 201.15 ? 16  GLY H N   1 
ATOM 104  C CA  . GLY A 1 16  ? 334.493 333.931 497.038 1.00 201.15 ? 16  GLY H CA  1 
ATOM 105  C C   . GLY A 1 16  ? 334.272 334.592 495.689 1.00 201.15 ? 16  GLY H C   1 
ATOM 106  O O   . GLY A 1 16  ? 335.068 334.467 494.756 1.00 201.15 ? 16  GLY H O   1 
ATOM 107  N N   . SER A 1 17  ? 333.151 335.305 495.594 1.00 201.92 ? 17  SER H N   1 
ATOM 108  C CA  . SER A 1 17  ? 332.743 335.992 494.379 1.00 201.92 ? 17  SER H CA  1 
ATOM 109  C C   . SER A 1 17  ? 332.168 337.362 494.713 1.00 201.92 ? 17  SER H C   1 
ATOM 110  O O   . SER A 1 17  ? 331.876 337.672 495.871 1.00 201.92 ? 17  SER H O   1 
ATOM 111  C CB  . SER A 1 17  ? 331.707 335.178 493.600 1.00 201.92 ? 17  SER H CB  1 
ATOM 112  O OG  . SER A 1 17  ? 331.271 335.887 492.454 1.00 201.92 ? 17  SER H OG  1 
ATOM 113  N N   . LEU A 1 18  ? 331.999 338.176 493.670 1.00 203.34 ? 18  LEU H N   1 
ATOM 114  C CA  . LEU A 1 18  ? 331.471 339.528 493.802 1.00 203.34 ? 18  LEU H CA  1 
ATOM 115  C C   . LEU A 1 18  ? 330.970 339.974 492.434 1.00 203.34 ? 18  LEU H C   1 
ATOM 116  O O   . LEU A 1 18  ? 331.537 339.590 491.409 1.00 203.34 ? 18  LEU H O   1 
ATOM 117  C CB  . LEU A 1 18  ? 332.548 340.486 494.331 1.00 203.34 ? 18  LEU H CB  1 
ATOM 118  C CG  . LEU A 1 18  ? 332.263 341.972 494.539 1.00 203.34 ? 18  LEU H CG  1 
ATOM 119  C CD1 . LEU A 1 18  ? 330.949 342.197 495.269 1.00 203.34 ? 18  LEU H CD1 1 
ATOM 120  C CD2 . LEU A 1 18  ? 333.403 342.593 495.311 1.00 203.34 ? 18  LEU H CD2 1 
ATOM 121  N N   . SER A 1 19  ? 329.902 340.768 492.421 1.00 199.81 ? 19  SER H N   1 
ATOM 122  C CA  . SER A 1 19  ? 329.314 341.281 491.189 1.00 199.81 ? 19  SER H CA  1 
ATOM 123  C C   . SER A 1 19  ? 329.129 342.786 491.311 1.00 199.81 ? 19  SER H C   1 
ATOM 124  O O   . SER A 1 19  ? 328.318 343.249 492.119 1.00 199.81 ? 19  SER H O   1 
ATOM 125  C CB  . SER A 1 19  ? 327.976 340.603 490.903 1.00 199.81 ? 19  SER H CB  1 
ATOM 126  O OG  . SER A 1 19  ? 327.025 340.936 491.898 1.00 199.81 ? 19  SER H OG  1 
ATOM 127  N N   . LEU A 1 20  ? 329.871 343.544 490.509 1.00 192.78 ? 20  LEU H N   1 
ATOM 128  C CA  . LEU A 1 20  ? 329.732 344.991 490.485 1.00 192.78 ? 20  LEU H CA  1 
ATOM 129  C C   . LEU A 1 20  ? 328.676 345.407 489.467 1.00 192.78 ? 20  LEU H C   1 
ATOM 130  O O   . LEU A 1 20  ? 328.284 344.639 488.588 1.00 192.78 ? 20  LEU H O   1 
ATOM 131  C CB  . LEU A 1 20  ? 331.067 345.658 490.157 1.00 192.78 ? 20  LEU H CB  1 
ATOM 132  C CG  . LEU A 1 20  ? 332.194 345.596 491.188 1.00 192.78 ? 20  LEU H CG  1 
ATOM 133  C CD1 . LEU A 1 20  ? 333.176 346.724 490.942 1.00 192.78 ? 20  LEU H CD1 1 
ATOM 134  C CD2 . LEU A 1 20  ? 331.660 345.659 492.607 1.00 192.78 ? 20  LEU H CD2 1 
ATOM 135  N N   . SER A 1 21  ? 328.219 346.651 489.591 1.00 193.07 ? 21  SER H N   1 
ATOM 136  C CA  . SER A 1 21  ? 327.214 347.184 488.682 1.00 193.07 ? 21  SER H CA  1 
ATOM 137  C C   . SER A 1 21  ? 327.525 348.644 488.400 1.00 193.07 ? 21  SER H C   1 
ATOM 138  O O   . SER A 1 21  ? 327.678 349.439 489.331 1.00 193.07 ? 21  SER H O   1 
ATOM 139  C CB  . SER A 1 21  ? 325.807 347.042 489.266 1.00 193.07 ? 21  SER H CB  1 
ATOM 140  O OG  . SER A 1 21  ? 325.280 345.756 488.999 1.00 193.07 ? 21  SER H OG  1 
ATOM 141  N N   . CYS A 1 22  ? 327.610 348.986 487.118 1.00 193.67 ? 22  CYS H N   1 
ATOM 142  C CA  . CYS A 1 22  ? 327.974 350.325 486.675 1.00 193.67 ? 22  CYS H CA  1 
ATOM 143  C C   . CYS A 1 22  ? 326.909 350.822 485.710 1.00 193.67 ? 22  CYS H C   1 
ATOM 144  O O   . CYS A 1 22  ? 326.723 350.244 484.634 1.00 193.67 ? 22  CYS H O   1 
ATOM 145  C CB  . CYS A 1 22  ? 329.351 350.323 486.011 1.00 193.67 ? 22  CYS H CB  1 
ATOM 146  S SG  . CYS A 1 22  ? 330.043 351.955 485.700 1.00 193.67 ? 22  CYS H SG  1 
ATOM 147  N N   . ALA A 1 23  ? 326.218 351.892 486.091 1.00 193.67 ? 23  ALA H N   1 
ATOM 148  C CA  . ALA A 1 23  ? 325.099 352.420 485.324 1.00 193.67 ? 23  ALA H CA  1 
ATOM 149  C C   . ALA A 1 23  ? 325.560 353.547 484.408 1.00 193.67 ? 23  ALA H C   1 
ATOM 150  O O   . ALA A 1 23  ? 326.563 354.214 484.683 1.00 193.67 ? 23  ALA H O   1 
ATOM 151  C CB  . ALA A 1 23  ? 323.995 352.923 486.254 1.00 193.67 ? 23  ALA H CB  1 
ATOM 152  N N   . ALA A 1 24  ? 324.816 353.759 483.324 1.00 189.43 ? 24  ALA H N   1 
ATOM 153  C CA  . ALA A 1 24  ? 325.166 354.732 482.298 1.00 189.43 ? 24  ALA H CA  1 
ATOM 154  C C   . ALA A 1 24  ? 324.018 355.705 482.072 1.00 189.43 ? 24  ALA H C   1 
ATOM 155  O O   . ALA A 1 24  ? 322.850 355.308 482.058 1.00 189.43 ? 24  ALA H O   1 
ATOM 156  C CB  . ALA A 1 24  ? 325.517 354.038 480.985 1.00 189.43 ? 24  ALA H CB  1 
ATOM 157  N N   . SER A 1 25  ? 324.358 356.978 481.885 1.00 183.47 ? 25  SER H N   1 
ATOM 158  C CA  . SER A 1 25  ? 323.358 358.014 481.677 1.00 183.47 ? 25  SER H CA  1 
ATOM 159  C C   . SER A 1 25  ? 323.985 359.174 480.924 1.00 183.47 ? 25  SER H C   1 
ATOM 160  O O   . SER A 1 25  ? 325.101 359.594 481.235 1.00 183.47 ? 25  SER H O   1 
ATOM 161  C CB  . SER A 1 25  ? 322.782 358.515 483.002 1.00 183.47 ? 25  SER H CB  1 
ATOM 162  O OG  . SER A 1 25  ? 323.563 359.578 483.516 1.00 183.47 ? 25  SER H OG  1 
ATOM 163  N N   . GLY A 1 26  ? 323.253 359.696 479.944 1.00 179.05 ? 26  GLY H N   1 
ATOM 164  C CA  . GLY A 1 26  ? 323.701 360.826 479.157 1.00 179.05 ? 26  GLY H CA  1 
ATOM 165  C C   . GLY A 1 26  ? 324.117 360.492 477.744 1.00 179.05 ? 26  GLY H C   1 
ATOM 166  O O   . GLY A 1 26  ? 324.515 361.401 477.006 1.00 179.05 ? 26  GLY H O   1 
ATOM 167  N N   . PHE A 1 27  ? 324.040 359.229 477.339 1.00 177.78 ? 27  PHE H N   1 
ATOM 168  C CA  . PHE A 1 27  ? 324.437 358.832 475.997 1.00 177.78 ? 27  PHE H CA  1 
ATOM 169  C C   . PHE A 1 27  ? 323.699 357.556 475.629 1.00 177.78 ? 27  PHE H C   1 
ATOM 170  O O   . PHE A 1 27  ? 323.167 356.850 476.488 1.00 177.78 ? 27  PHE H O   1 
ATOM 171  C CB  . PHE A 1 27  ? 325.957 358.640 475.883 1.00 177.78 ? 27  PHE H CB  1 
ATOM 172  C CG  . PHE A 1 27  ? 326.526 357.602 476.820 1.00 177.78 ? 27  PHE H CG  1 
ATOM 173  C CD1 . PHE A 1 27  ? 326.925 357.950 478.099 1.00 177.78 ? 27  PHE H CD1 1 
ATOM 174  C CD2 . PHE A 1 27  ? 326.693 356.289 476.411 1.00 177.78 ? 27  PHE H CD2 1 
ATOM 175  C CE1 . PHE A 1 27  ? 327.454 357.007 478.953 1.00 177.78 ? 27  PHE H CE1 1 
ATOM 176  C CE2 . PHE A 1 27  ? 327.220 355.346 477.261 1.00 177.78 ? 27  PHE H CE2 1 
ATOM 177  C CZ  . PHE A 1 27  ? 327.603 355.706 478.531 1.00 177.78 ? 27  PHE H CZ  1 
ATOM 178  N N   . THR A 1 28  ? 323.680 357.268 474.333 1.00 184.95 ? 28  THR H N   1 
ATOM 179  C CA  . THR A 1 28  ? 323.200 355.983 473.849 1.00 184.95 ? 28  THR H CA  1 
ATOM 180  C C   . THR A 1 28  ? 324.260 354.937 474.156 1.00 184.95 ? 28  THR H C   1 
ATOM 181  O O   . THR A 1 28  ? 325.415 355.080 473.744 1.00 184.95 ? 28  THR H O   1 
ATOM 182  C CB  . THR A 1 28  ? 322.912 356.039 472.352 1.00 184.95 ? 28  THR H CB  1 
ATOM 183  O OG1 . THR A 1 28  ? 322.284 357.286 472.031 1.00 184.95 ? 28  THR H OG1 1 
ATOM 184  C CG2 . THR A 1 28  ? 321.997 354.895 471.952 1.00 184.95 ? 28  THR H CG2 1 
ATOM 185  N N   . PHE A 1 29  ? 323.870 353.895 474.882 1.00 183.24 ? 29  PHE H N   1 
ATOM 186  C CA  . PHE A 1 29  ? 324.836 352.949 475.419 1.00 183.24 ? 29  PHE H CA  1 
ATOM 187  C C   . PHE A 1 29  ? 325.468 352.064 474.358 1.00 183.24 ? 29  PHE H C   1 
ATOM 188  O O   . PHE A 1 29  ? 326.574 351.560 474.572 1.00 183.24 ? 29  PHE H O   1 
ATOM 189  C CB  . PHE A 1 29  ? 324.166 352.074 476.475 1.00 183.24 ? 29  PHE H CB  1 
ATOM 190  C CG  . PHE A 1 29  ? 325.129 351.345 477.348 1.00 183.24 ? 29  PHE H CG  1 
ATOM 191  C CD1 . PHE A 1 29  ? 326.254 351.984 477.831 1.00 183.24 ? 29  PHE H CD1 1 
ATOM 192  C CD2 . PHE A 1 29  ? 324.912 350.023 477.686 1.00 183.24 ? 29  PHE H CD2 1 
ATOM 193  C CE1 . PHE A 1 29  ? 327.147 351.320 478.636 1.00 183.24 ? 29  PHE H CE1 1 
ATOM 194  C CE2 . PHE A 1 29  ? 325.805 349.349 478.492 1.00 183.24 ? 29  PHE H CE2 1 
ATOM 195  C CZ  . PHE A 1 29  ? 326.925 350.000 478.967 1.00 183.24 ? 29  PHE H CZ  1 
ATOM 196  N N   . THR A 1 30  ? 324.809 351.873 473.218 1.00 168.23 ? 30  THR H N   1 
ATOM 197  C CA  . THR A 1 30  ? 325.247 350.895 472.233 1.00 168.23 ? 30  THR H CA  1 
ATOM 198  C C   . THR A 1 30  ? 326.146 351.491 471.160 1.00 168.23 ? 30  THR H C   1 
ATOM 199  O O   . THR A 1 30  ? 326.259 350.921 470.068 1.00 168.23 ? 30  THR H O   1 
ATOM 200  C CB  . THR A 1 30  ? 324.034 350.220 471.594 1.00 168.23 ? 30  THR H CB  1 
ATOM 201  O OG1 . THR A 1 30  ? 323.070 351.215 471.233 1.00 168.23 ? 30  THR H OG1 1 
ATOM 202  C CG2 . THR A 1 30  ? 323.399 349.245 472.574 1.00 168.23 ? 30  THR H CG2 1 
ATOM 203  N N   . ASP A 1 31  ? 326.796 352.619 471.436 1.00 162.14 ? 31  ASP H N   1 
ATOM 204  C CA  . ASP A 1 31  ? 327.695 353.227 470.468 1.00 162.14 ? 31  ASP H CA  1 
ATOM 205  C C   . ASP A 1 31  ? 329.080 353.540 471.005 1.00 162.14 ? 31  ASP H C   1 
ATOM 206  O O   . ASP A 1 31  ? 329.927 353.991 470.228 1.00 162.14 ? 31  ASP H O   1 
ATOM 207  C CB  . ASP A 1 31  ? 327.093 354.524 469.908 1.00 162.14 ? 31  ASP H CB  1 
ATOM 208  C CG  . ASP A 1 31  ? 325.941 354.270 468.964 1.00 162.14 ? 31  ASP H CG  1 
ATOM 209  O OD1 . ASP A 1 31  ? 325.931 353.206 468.311 1.00 162.14 ? 31  ASP H OD1 1 
ATOM 210  O OD2 . ASP A 1 31  ? 325.047 355.136 468.868 1.00 162.14 ? 31  ASP H OD2 1 
ATOM 211  N N   . TYR A 1 32  ? 329.345 353.324 472.286 1.00 161.66 ? 32  TYR H N   1 
ATOM 212  C CA  . TYR A 1 32  ? 330.641 353.649 472.852 1.00 161.66 ? 32  TYR H CA  1 
ATOM 213  C C   . TYR A 1 32  ? 331.221 352.439 473.566 1.00 161.66 ? 32  TYR H C   1 
ATOM 214  O O   . TYR A 1 32  ? 330.503 351.650 474.183 1.00 161.66 ? 32  TYR H O   1 
ATOM 215  C CB  . TYR A 1 32  ? 330.550 354.832 473.810 1.00 161.66 ? 32  TYR H CB  1 
ATOM 216  C CG  . TYR A 1 32  ? 329.967 356.059 473.169 1.00 161.66 ? 32  TYR H CG  1 
ATOM 217  C CD1 . TYR A 1 32  ? 330.544 356.608 472.037 1.00 161.66 ? 32  TYR H CD1 1 
ATOM 218  C CD2 . TYR A 1 32  ? 328.850 356.679 473.702 1.00 161.66 ? 32  TYR H CD2 1 
ATOM 219  C CE1 . TYR A 1 32  ? 330.016 357.735 471.442 1.00 161.66 ? 32  TYR H CE1 1 
ATOM 220  C CE2 . TYR A 1 32  ? 328.313 357.808 473.118 1.00 161.66 ? 32  TYR H CE2 1 
ATOM 221  C CZ  . TYR A 1 32  ? 328.902 358.332 471.989 1.00 161.66 ? 32  TYR H CZ  1 
ATOM 222  O OH  . TYR A 1 32  ? 328.373 359.456 471.402 1.00 161.66 ? 32  TYR H OH  1 
ATOM 223  N N   . TYR A 1 33  ? 332.537 352.308 473.465 1.00 154.82 ? 33  TYR H N   1 
ATOM 224  C CA  . TYR A 1 33  ? 333.241 351.209 474.103 1.00 154.82 ? 33  TYR H CA  1 
ATOM 225  C C   . TYR A 1 33  ? 333.315 351.443 475.608 1.00 154.82 ? 33  TYR H C   1 
ATOM 226  O O   . TYR A 1 33  ? 333.497 352.573 476.067 1.00 154.82 ? 33  TYR H O   1 
ATOM 227  C CB  . TYR A 1 33  ? 334.646 351.076 473.512 1.00 154.82 ? 33  TYR H CB  1 
ATOM 228  C CG  . TYR A 1 33  ? 334.724 350.431 472.138 1.00 154.82 ? 33  TYR H CG  1 
ATOM 229  C CD1 . TYR A 1 33  ? 334.117 351.010 471.030 1.00 154.82 ? 33  TYR H CD1 1 
ATOM 230  C CD2 . TYR A 1 33  ? 335.442 349.261 471.946 1.00 154.82 ? 33  TYR H CD2 1 
ATOM 231  C CE1 . TYR A 1 33  ? 334.199 350.425 469.782 1.00 154.82 ? 33  TYR H CE1 1 
ATOM 232  C CE2 . TYR A 1 33  ? 335.533 348.671 470.698 1.00 154.82 ? 33  TYR H CE2 1 
ATOM 233  C CZ  . TYR A 1 33  ? 334.910 349.259 469.622 1.00 154.82 ? 33  TYR H CZ  1 
ATOM 234  O OH  . TYR A 1 33  ? 334.995 348.677 468.379 1.00 154.82 ? 33  TYR H OH  1 
ATOM 235  N N   . MET A 1 34  ? 333.175 350.367 476.377 1.00 166.43 ? 34  MET H N   1 
ATOM 236  C CA  . MET A 1 34  ? 333.130 350.421 477.835 1.00 166.43 ? 34  MET H CA  1 
ATOM 237  C C   . MET A 1 34  ? 334.349 349.716 478.404 1.00 166.43 ? 34  MET H C   1 
ATOM 238  O O   . MET A 1 34  ? 334.539 348.523 478.161 1.00 166.43 ? 34  MET H O   1 
ATOM 239  C CB  . MET A 1 34  ? 331.857 349.759 478.355 1.00 166.43 ? 34  MET H CB  1 
ATOM 240  C CG  . MET A 1 34  ? 330.670 350.672 478.645 1.00 166.43 ? 34  MET H CG  1 
ATOM 241  S SD  . MET A 1 34  ? 330.881 351.846 480.000 1.00 166.43 ? 34  MET H SD  1 
ATOM 242  C CE  . MET A 1 34  ? 331.323 353.346 479.144 1.00 166.43 ? 34  MET H CE  1 
ATOM 243  N N   . ASN A 1 35  ? 335.149 350.434 479.184 1.00 171.04 ? 35  ASN H N   1 
ATOM 244  C CA  . ASN A 1 35  ? 336.381 349.891 479.729 1.00 171.04 ? 35  ASN H CA  1 
ATOM 245  C C   . ASN A 1 35  ? 336.285 349.741 481.246 1.00 171.04 ? 35  ASN H C   1 
ATOM 246  O O   . ASN A 1 35  ? 335.310 350.145 481.880 1.00 171.04 ? 35  ASN H O   1 
ATOM 247  C CB  . ASN A 1 35  ? 337.561 350.781 479.346 1.00 171.04 ? 35  ASN H CB  1 
ATOM 248  C CG  . ASN A 1 35  ? 337.983 350.594 477.910 1.00 171.04 ? 35  ASN H CG  1 
ATOM 249  O OD1 . ASN A 1 35  ? 339.030 350.016 477.631 1.00 171.04 ? 35  ASN H OD1 1 
ATOM 250  N ND2 . ASN A 1 35  ? 337.167 351.080 476.986 1.00 171.04 ? 35  ASN H ND2 1 
ATOM 251  N N   . TRP A 1 36  ? 337.328 349.157 481.833 1.00 175.02 ? 36  TRP H N   1 
ATOM 252  C CA  . TRP A 1 36  ? 337.393 348.926 483.273 1.00 175.02 ? 36  TRP H CA  1 
ATOM 253  C C   . TRP A 1 36  ? 338.848 348.984 483.704 1.00 175.02 ? 36  TRP H C   1 
ATOM 254  O O   . TRP A 1 36  ? 339.651 348.153 483.273 1.00 175.02 ? 36  TRP H O   1 
ATOM 255  C CB  . TRP A 1 36  ? 336.802 347.572 483.641 1.00 175.02 ? 36  TRP H CB  1 
ATOM 256  C CG  . TRP A 1 36  ? 335.329 347.518 483.626 1.00 175.02 ? 36  TRP H CG  1 
ATOM 257  C CD1 . TRP A 1 36  ? 334.542 347.177 482.578 1.00 175.02 ? 36  TRP H CD1 1 
ATOM 258  C CD2 . TRP A 1 36  ? 334.450 347.789 484.718 1.00 175.02 ? 36  TRP H CD2 1 
ATOM 259  N NE1 . TRP A 1 36  ? 333.223 347.219 482.942 1.00 175.02 ? 36  TRP H NE1 1 
ATOM 260  C CE2 . TRP A 1 36  ? 333.140 347.591 484.256 1.00 175.02 ? 36  TRP H CE2 1 
ATOM 261  C CE3 . TRP A 1 36  ? 334.644 348.169 486.046 1.00 175.02 ? 36  TRP H CE3 1 
ATOM 262  C CZ2 . TRP A 1 36  ? 332.028 347.774 485.067 1.00 175.02 ? 36  TRP H CZ2 1 
ATOM 263  C CZ3 . TRP A 1 36  ? 333.540 348.352 486.850 1.00 175.02 ? 36  TRP H CZ3 1 
ATOM 264  C CH2 . TRP A 1 36  ? 332.249 348.152 486.360 1.00 175.02 ? 36  TRP H CH2 1 
ATOM 265  N N   . VAL A 1 37  ? 339.190 349.950 484.552 1.00 178.98 ? 37  VAL H N   1 
ATOM 266  C CA  . VAL A 1 37  ? 340.561 350.144 485.009 1.00 178.98 ? 37  VAL H CA  1 
ATOM 267  C C   . VAL A 1 37  ? 340.561 350.136 486.528 1.00 178.98 ? 37  VAL H C   1 
ATOM 268  O O   . VAL A 1 37  ? 339.794 350.877 487.153 1.00 178.98 ? 37  VAL H O   1 
ATOM 269  C CB  . VAL A 1 37  ? 341.166 351.454 484.479 1.00 178.98 ? 37  VAL H CB  1 
ATOM 270  C CG1 . VAL A 1 37  ? 342.558 351.668 485.037 1.00 178.98 ? 37  VAL H CG1 1 
ATOM 271  C CG2 . VAL A 1 37  ? 341.216 351.445 482.966 1.00 178.98 ? 37  VAL H CG2 1 
ATOM 272  N N   . ARG A 1 38  ? 341.413 349.305 487.120 1.00 182.67 ? 38  ARG H N   1 
ATOM 273  C CA  . ARG A 1 38  ? 341.614 349.295 488.559 1.00 182.67 ? 38  ARG H CA  1 
ATOM 274  C C   . ARG A 1 38  ? 342.896 350.034 488.922 1.00 182.67 ? 38  ARG H C   1 
ATOM 275  O O   . ARG A 1 38  ? 343.849 350.103 488.143 1.00 182.67 ? 38  ARG H O   1 
ATOM 276  C CB  . ARG A 1 38  ? 341.655 347.864 489.106 1.00 182.67 ? 38  ARG H CB  1 
ATOM 277  C CG  . ARG A 1 38  ? 342.854 347.050 488.669 1.00 182.67 ? 38  ARG H CG  1 
ATOM 278  C CD  . ARG A 1 38  ? 342.907 345.713 489.379 1.00 182.67 ? 38  ARG H CD  1 
ATOM 279  N NE  . ARG A 1 38  ? 344.033 344.910 488.914 1.00 182.67 ? 38  ARG H NE  1 
ATOM 280  C CZ  . ARG A 1 38  ? 344.400 343.751 489.451 1.00 182.67 ? 38  ARG H CZ  1 
ATOM 281  N NH1 . ARG A 1 38  ? 343.732 343.252 490.482 1.00 182.67 ? 38  ARG H NH1 1 
ATOM 282  N NH2 . ARG A 1 38  ? 345.439 343.092 488.956 1.00 182.67 ? 38  ARG H NH2 1 
ATOM 283  N N   . GLN A 1 39  ? 342.899 350.608 490.126 1.00 186.63 ? 39  GLN H N   1 
ATOM 284  C CA  . GLN A 1 39  ? 344.063 351.311 490.610 1.00 186.63 ? 39  GLN H CA  1 
ATOM 285  C C   . GLN A 1 39  ? 344.296 350.909 492.057 1.00 186.63 ? 39  GLN H C   1 
ATOM 286  O O   . GLN A 1 39  ? 343.423 351.158 492.904 1.00 186.63 ? 39  GLN H O   1 
ATOM 287  C CB  . GLN A 1 39  ? 343.925 352.831 490.520 1.00 186.63 ? 39  GLN H CB  1 
ATOM 288  C CG  . GLN A 1 39  ? 345.177 353.574 490.967 1.00 186.63 ? 39  GLN H CG  1 
ATOM 289  C CD  . GLN A 1 39  ? 344.901 355.006 491.376 1.00 186.63 ? 39  GLN H CD  1 
ATOM 290  O OE1 . GLN A 1 39  ? 343.757 355.387 491.614 1.00 186.63 ? 39  GLN H OE1 1 
ATOM 291  N NE2 . GLN A 1 39  ? 345.955 355.807 491.464 1.00 186.63 ? 39  GLN H NE2 1 
ATOM 292  N N   . PRO A 1 40  ? 345.436 350.302 492.367 1.00 187.64 ? 40  PRO H N   1 
ATOM 293  C CA  . PRO A 1 40  ? 345.781 350.061 493.771 1.00 187.64 ? 40  PRO H CA  1 
ATOM 294  C C   . PRO A 1 40  ? 346.111 351.365 494.470 1.00 187.64 ? 40  PRO H C   1 
ATOM 295  O O   . PRO A 1 40  ? 346.444 352.353 493.808 1.00 187.64 ? 40  PRO H O   1 
ATOM 296  C CB  . PRO A 1 40  ? 347.002 349.135 493.684 1.00 187.64 ? 40  PRO H CB  1 
ATOM 297  C CG  . PRO A 1 40  ? 347.025 348.640 492.260 1.00 187.64 ? 40  PRO H CG  1 
ATOM 298  C CD  . PRO A 1 40  ? 346.436 349.737 491.450 1.00 187.64 ? 40  PRO H CD  1 
ATOM 299  N N   . SER A 1 41  ? 346.029 351.380 495.799 1.00 186.19 ? 41  SER H N   1 
ATOM 300  C CA  . SER A 1 41  ? 346.172 352.611 496.566 1.00 186.19 ? 41  SER H CA  1 
ATOM 301  C C   . SER A 1 41  ? 347.600 353.143 496.516 1.00 186.19 ? 41  SER H C   1 
ATOM 302  O O   . SER A 1 41  ? 348.502 352.589 497.151 1.00 186.19 ? 41  SER H O   1 
ATOM 303  C CB  . SER A 1 41  ? 345.740 352.379 498.015 1.00 186.19 ? 41  SER H CB  1 
ATOM 304  O OG  . SER A 1 41  ? 344.337 352.211 498.108 1.00 186.19 ? 41  SER H OG  1 
ATOM 305  N N   . GLY A 1 42  ? 347.809 354.212 495.752 1.00 186.54 ? 42  GLY H N   1 
ATOM 306  C CA  . GLY A 1 42  ? 349.128 354.804 495.625 1.00 186.54 ? 42  GLY H CA  1 
ATOM 307  C C   . GLY A 1 42  ? 350.051 354.094 494.660 1.00 186.54 ? 42  GLY H C   1 
ATOM 308  O O   . GLY A 1 42  ? 351.273 354.237 494.764 1.00 186.54 ? 42  GLY H O   1 
ATOM 309  N N   . LYS A 1 43  ? 349.504 353.340 493.716 1.00 181.34 ? 43  LYS H N   1 
ATOM 310  C CA  . LYS A 1 43  ? 350.296 352.565 492.773 1.00 181.34 ? 43  LYS H CA  1 
ATOM 311  C C   . LYS A 1 43  ? 349.845 352.904 491.349 1.00 181.34 ? 43  LYS H C   1 
ATOM 312  O O   . LYS A 1 43  ? 348.836 353.585 491.144 1.00 181.34 ? 43  LYS H O   1 
ATOM 313  C CB  . LYS A 1 43  ? 350.170 351.073 493.097 1.00 181.34 ? 43  LYS H CB  1 
ATOM 314  C CG  . LYS A 1 43  ? 351.369 350.220 492.704 1.00 181.34 ? 43  LYS H CG  1 
ATOM 315  C CD  . LYS A 1 43  ? 351.275 348.830 493.299 1.00 181.34 ? 43  LYS H CD  1 
ATOM 316  C CE  . LYS A 1 43  ? 352.340 347.927 492.716 1.00 181.34 ? 43  LYS H CE  1 
ATOM 317  N NZ  . LYS A 1 43  ? 353.707 348.448 492.979 1.00 181.34 ? 43  LYS H NZ  1 
ATOM 318  N N   . ALA A 1 44  ? 350.609 352.429 490.367 1.00 182.79 ? 44  ALA H N   1 
ATOM 319  C CA  . ALA A 1 44  ? 350.339 352.696 488.963 1.00 182.79 ? 44  ALA H CA  1 
ATOM 320  C C   . ALA A 1 44  ? 349.054 352.007 488.505 1.00 182.79 ? 44  ALA H C   1 
ATOM 321  O O   . ALA A 1 44  ? 348.544 351.084 489.146 1.00 182.79 ? 44  ALA H O   1 
ATOM 322  C CB  . ALA A 1 44  ? 351.514 352.239 488.100 1.00 182.79 ? 44  ALA H CB  1 
ATOM 323  N N   . LEU A 1 45  ? 348.532 352.474 487.376 1.00 179.16 ? 45  LEU H N   1 
ATOM 324  C CA  . LEU A 1 45  ? 347.269 351.984 486.851 1.00 179.16 ? 45  LEU H CA  1 
ATOM 325  C C   . LEU A 1 45  ? 347.470 350.700 486.051 1.00 179.16 ? 45  LEU H C   1 
ATOM 326  O O   . LEU A 1 45  ? 348.529 350.454 485.471 1.00 179.16 ? 45  LEU H O   1 
ATOM 327  C CB  . LEU A 1 45  ? 346.610 353.039 485.964 1.00 179.16 ? 45  LEU H CB  1 
ATOM 328  C CG  . LEU A 1 45  ? 345.528 353.928 486.578 1.00 179.16 ? 45  LEU H CG  1 
ATOM 329  C CD1 . LEU A 1 45  ? 346.122 354.867 487.607 1.00 179.16 ? 45  LEU H CD1 1 
ATOM 330  C CD2 . LEU A 1 45  ? 344.807 354.711 485.495 1.00 179.16 ? 45  LEU H CD2 1 
ATOM 331  N N   . GLU A 1 46  ? 346.423 349.879 486.025 1.00 175.58 ? 46  GLU H N   1 
ATOM 332  C CA  . GLU A 1 46  ? 346.387 348.672 485.214 1.00 175.58 ? 46  GLU H CA  1 
ATOM 333  C C   . GLU A 1 46  ? 345.005 348.535 484.598 1.00 175.58 ? 46  GLU H C   1 
ATOM 334  O O   . GLU A 1 46  ? 343.993 348.679 485.287 1.00 175.58 ? 46  GLU H O   1 
ATOM 335  C CB  . GLU A 1 46  ? 346.710 347.421 486.034 1.00 175.58 ? 46  GLU H CB  1 
ATOM 336  C CG  . GLU A 1 46  ? 348.178 347.234 486.358 1.00 175.58 ? 46  GLU H CG  1 
ATOM 337  C CD  . GLU A 1 46  ? 348.400 346.177 487.420 1.00 175.58 ? 46  GLU H CD  1 
ATOM 338  O OE1 . GLU A 1 46  ? 347.463 345.396 487.685 1.00 175.58 ? 46  GLU H OE1 1 
ATOM 339  O OE2 . GLU A 1 46  ? 349.508 346.128 487.995 1.00 175.58 ? 46  GLU H OE2 1 
ATOM 340  N N   . TRP A 1 47  ? 344.970 348.248 483.304 1.00 165.87 ? 47  TRP H N   1 
ATOM 341  C CA  . TRP A 1 47  ? 343.729 348.107 482.558 1.00 165.87 ? 47  TRP H CA  1 
ATOM 342  C C   . TRP A 1 47  ? 343.321 346.643 482.515 1.00 165.87 ? 47  TRP H C   1 
ATOM 343  O O   . TRP A 1 47  ? 344.163 345.759 482.338 1.00 165.87 ? 47  TRP H O   1 
ATOM 344  C CB  . TRP A 1 47  ? 343.904 348.656 481.145 1.00 165.87 ? 47  TRP H CB  1 
ATOM 345  C CG  . TRP A 1 47  ? 342.963 348.115 480.125 1.00 165.87 ? 47  TRP H CG  1 
ATOM 346  C CD1 . TRP A 1 47  ? 341.674 348.492 479.919 1.00 165.87 ? 47  TRP H CD1 1 
ATOM 347  C CD2 . TRP A 1 47  ? 343.247 347.107 479.151 1.00 165.87 ? 47  TRP H CD2 1 
ATOM 348  N NE1 . TRP A 1 47  ? 341.132 347.779 478.879 1.00 165.87 ? 47  TRP H NE1 1 
ATOM 349  C CE2 . TRP A 1 47  ? 342.080 346.920 478.391 1.00 165.87 ? 47  TRP H CE2 1 
ATOM 350  C CE3 . TRP A 1 47  ? 344.375 346.338 478.854 1.00 165.87 ? 47  TRP H CE3 1 
ATOM 351  C CZ2 . TRP A 1 47  ? 342.009 346.002 477.349 1.00 165.87 ? 47  TRP H CZ2 1 
ATOM 352  C CZ3 . TRP A 1 47  ? 344.305 345.431 477.818 1.00 165.87 ? 47  TRP H CZ3 1 
ATOM 353  C CH2 . TRP A 1 47  ? 343.129 345.267 477.081 1.00 165.87 ? 47  TRP H CH2 1 
ATOM 354  N N   . LEU A 1 48  ? 342.026 346.387 482.684 1.00 169.92 ? 48  LEU H N   1 
ATOM 355  C CA  . LEU A 1 48  ? 341.514 345.025 482.733 1.00 169.92 ? 48  LEU H CA  1 
ATOM 356  C C   . LEU A 1 48  ? 341.060 344.511 481.379 1.00 169.92 ? 48  LEU H C   1 
ATOM 357  O O   . LEU A 1 48  ? 341.598 343.521 480.878 1.00 169.92 ? 48  LEU H O   1 
ATOM 358  C CB  . LEU A 1 48  ? 340.345 344.933 483.720 1.00 169.92 ? 48  LEU H CB  1 
ATOM 359  C CG  . LEU A 1 48  ? 340.619 345.206 485.196 1.00 169.92 ? 48  LEU H CG  1 
ATOM 360  C CD1 . LEU A 1 48  ? 339.448 344.716 486.023 1.00 169.92 ? 48  LEU H CD1 1 
ATOM 361  C CD2 . LEU A 1 48  ? 341.912 344.547 485.648 1.00 169.92 ? 48  LEU H CD2 1 
ATOM 362  N N   . GLY A 1 49  ? 340.082 345.165 480.769 1.00 164.00 ? 49  GLY H N   1 
ATOM 363  C CA  . GLY A 1 49  ? 339.512 344.676 479.533 1.00 164.00 ? 49  GLY H CA  1 
ATOM 364  C C   . GLY A 1 49  ? 338.230 345.397 479.195 1.00 164.00 ? 49  GLY H C   1 
ATOM 365  O O   . GLY A 1 49  ? 337.571 345.935 480.087 1.00 164.00 ? 49  GLY H O   1 
ATOM 366  N N   . PHE A 1 50  ? 337.851 345.411 477.923 1.00 155.63 ? 50  PHE H N   1 
ATOM 367  C CA  . PHE A 1 50  ? 336.738 346.239 477.499 1.00 155.63 ? 50  PHE H CA  1 
ATOM 368  C C   . PHE A 1 50  ? 335.674 345.408 476.798 1.00 155.63 ? 50  PHE H C   1 
ATOM 369  O O   . PHE A 1 50  ? 335.747 344.179 476.728 1.00 155.63 ? 50  PHE H O   1 
ATOM 370  C CB  . PHE A 1 50  ? 337.205 347.396 476.599 1.00 155.63 ? 50  PHE H CB  1 
ATOM 371  C CG  . PHE A 1 50  ? 337.793 346.973 475.284 1.00 155.63 ? 50  PHE H CG  1 
ATOM 372  C CD1 . PHE A 1 50  ? 339.132 346.648 475.185 1.00 155.63 ? 50  PHE H CD1 1 
ATOM 373  C CD2 . PHE A 1 50  ? 337.020 346.957 474.135 1.00 155.63 ? 50  PHE H CD2 1 
ATOM 374  C CE1 . PHE A 1 50  ? 339.678 346.282 473.977 1.00 155.63 ? 50  PHE H CE1 1 
ATOM 375  C CE2 . PHE A 1 50  ? 337.560 346.587 472.929 1.00 155.63 ? 50  PHE H CE2 1 
ATOM 376  C CZ  . PHE A 1 50  ? 338.891 346.254 472.849 1.00 155.63 ? 50  PHE H CZ  1 
ATOM 377  N N   . LEU A 1 51  ? 334.667 346.115 476.292 1.00 155.97 ? 51  LEU H N   1 
ATOM 378  C CA  . LEU A 1 51  ? 333.524 345.523 475.617 1.00 155.97 ? 51  LEU H CA  1 
ATOM 379  C C   . LEU A 1 51  ? 333.128 346.434 474.466 1.00 155.97 ? 51  LEU H C   1 
ATOM 380  O O   . LEU A 1 51  ? 332.997 347.647 474.651 1.00 155.97 ? 51  LEU H O   1 
ATOM 381  C CB  . LEU A 1 51  ? 332.353 345.341 476.586 1.00 155.97 ? 51  LEU H CB  1 
ATOM 382  C CG  . LEU A 1 51  ? 330.960 345.057 476.025 1.00 155.97 ? 51  LEU H CG  1 
ATOM 383  C CD1 . LEU A 1 51  ? 330.935 343.789 475.177 1.00 155.97 ? 51  LEU H CD1 1 
ATOM 384  C CD2 . LEU A 1 51  ? 329.956 344.963 477.155 1.00 155.97 ? 51  LEU H CD2 1 
ATOM 385  N N   . ARG A 1 52  ? 332.935 345.853 473.288 1.00 145.38 ? 52  ARG H N   1 
ATOM 386  C CA  . ARG A 1 52  ? 332.605 346.638 472.112 1.00 145.38 ? 52  ARG H CA  1 
ATOM 387  C C   . ARG A 1 52  ? 331.112 346.950 472.067 1.00 145.38 ? 52  ARG H C   1 
ATOM 388  O O   . ARG A 1 52  ? 330.318 346.457 472.869 1.00 145.38 ? 52  ARG H O   1 
ATOM 389  C CB  . ARG A 1 52  ? 333.031 345.904 470.849 1.00 145.38 ? 52  ARG H CB  1 
ATOM 390  C CG  . ARG A 1 52  ? 334.308 345.123 471.015 1.00 145.38 ? 52  ARG H CG  1 
ATOM 391  C CD  . ARG A 1 52  ? 335.105 345.133 469.741 1.00 145.38 ? 52  ARG H CD  1 
ATOM 392  N NE  . ARG A 1 52  ? 336.030 344.012 469.663 1.00 145.38 ? 52  ARG H NE  1 
ATOM 393  C CZ  . ARG A 1 52  ? 337.137 344.031 468.935 1.00 145.38 ? 52  ARG H CZ  1 
ATOM 394  N NH1 . ARG A 1 52  ? 337.442 345.111 468.238 1.00 145.38 ? 52  ARG H NH1 1 
ATOM 395  N NH2 . ARG A 1 52  ? 337.936 342.978 468.899 1.00 145.38 ? 52  ARG H NH2 1 
ATOM 396  N N   . ASN A 1 53  ? 330.736 347.780 471.101 1.00 147.97 ? 53  ASN H N   1 
ATOM 397  C CA  . ASN A 1 53  ? 329.366 348.253 470.973 1.00 147.97 ? 53  ASN H CA  1 
ATOM 398  C C   . ASN A 1 53  ? 328.554 347.282 470.121 1.00 147.97 ? 53  ASN H C   1 
ATOM 399  O O   . ASN A 1 53  ? 328.971 346.153 469.852 1.00 147.97 ? 53  ASN H O   1 
ATOM 400  C CB  . ASN A 1 53  ? 329.354 349.666 470.406 1.00 147.97 ? 53  ASN H CB  1 
ATOM 401  C CG  . ASN A 1 53  ? 330.331 349.839 469.270 1.00 147.97 ? 53  ASN H CG  1 
ATOM 402  O OD1 . ASN A 1 53  ? 330.913 348.871 468.784 1.00 147.97 ? 53  ASN H OD1 1 
ATOM 403  N ND2 . ASN A 1 53  ? 330.533 351.081 468.851 1.00 147.97 ? 53  ASN H ND2 1 
ATOM 404  N N   . LYS A 1 54  ? 327.368 347.721 469.693 1.00 144.39 ? 54  LYS H N   1 
ATOM 405  C CA  . LYS A 1 54  ? 326.465 346.845 468.954 1.00 144.39 ? 54  LYS H CA  1 
ATOM 406  C C   . LYS A 1 54  ? 326.955 346.592 467.534 1.00 144.39 ? 54  LYS H C   1 
ATOM 407  O O   . LYS A 1 54  ? 326.755 345.497 466.998 1.00 144.39 ? 54  LYS H O   1 
ATOM 408  C CB  . LYS A 1 54  ? 325.059 347.446 468.937 1.00 144.39 ? 54  LYS H CB  1 
ATOM 409  C CG  . LYS A 1 54  ? 323.987 346.511 468.406 1.00 144.39 ? 54  LYS H CG  1 
ATOM 410  C CD  . LYS A 1 54  ? 322.774 347.265 467.892 1.00 144.39 ? 54  LYS H CD  1 
ATOM 411  C CE  . LYS A 1 54  ? 322.060 346.468 466.809 1.00 144.39 ? 54  LYS H CE  1 
ATOM 412  N NZ  . LYS A 1 54  ? 321.418 347.335 465.785 1.00 144.39 ? 54  LYS H NZ  1 
ATOM 413  N N   . ALA A 1 55  ? 327.621 347.569 466.922 1.00 132.25 ? 55  ALA H N   1 
ATOM 414  C CA  . ALA A 1 55  ? 328.071 347.427 465.545 1.00 132.25 ? 55  ALA H CA  1 
ATOM 415  C C   . ALA A 1 55  ? 329.287 346.523 465.393 1.00 132.25 ? 55  ALA H C   1 
ATOM 416  O O   . ALA A 1 55  ? 329.660 346.209 464.259 1.00 132.25 ? 55  ALA H O   1 
ATOM 417  C CB  . ALA A 1 55  ? 328.384 348.800 464.954 1.00 132.25 ? 55  ALA H CB  1 
ATOM 418  N N   . ASN A 1 56  ? 329.913 346.096 466.489 1.00 136.24 ? 56  ASN H N   1 
ATOM 419  C CA  . ASN A 1 56  ? 331.070 345.212 466.419 1.00 136.24 ? 56  ASN H CA  1 
ATOM 420  C C   . ASN A 1 56  ? 330.781 343.822 466.966 1.00 136.24 ? 56  ASN H C   1 
ATOM 421  O O   . ASN A 1 56  ? 331.702 343.004 467.061 1.00 136.24 ? 56  ASN H O   1 
ATOM 422  C CB  . ASN A 1 56  ? 332.258 345.828 467.159 1.00 136.24 ? 56  ASN H CB  1 
ATOM 423  C CG  . ASN A 1 56  ? 333.023 346.816 466.306 1.00 136.24 ? 56  ASN H CG  1 
ATOM 424  O OD1 . ASN A 1 56  ? 333.246 347.958 466.705 1.00 136.24 ? 56  ASN H OD1 1 
ATOM 425  N ND2 . ASN A 1 56  ? 333.430 346.380 465.121 1.00 136.24 ? 56  ASN H ND2 1 
ATOM 426  N N   . GLY A 1 57  ? 329.539 343.535 467.335 1.00 143.51 ? 57  GLY H N   1 
ATOM 427  C CA  . GLY A 1 57  ? 329.145 342.198 467.718 1.00 143.51 ? 57  GLY H CA  1 
ATOM 428  C C   . GLY A 1 57  ? 329.323 341.833 469.176 1.00 143.51 ? 57  GLY H C   1 
ATOM 429  O O   . GLY A 1 57  ? 329.297 340.637 469.491 1.00 143.51 ? 57  GLY H O   1 
ATOM 430  N N   . TYR A 1 58  ? 329.531 342.819 470.060 1.00 154.09 ? 58  TYR H N   1 
ATOM 431  C CA  . TYR A 1 58  ? 329.558 342.648 471.520 1.00 154.09 ? 58  TYR H CA  1 
ATOM 432  C C   . TYR A 1 58  ? 330.665 341.706 471.985 1.00 154.09 ? 58  TYR H C   1 
ATOM 433  O O   . TYR A 1 58  ? 330.411 340.770 472.743 1.00 154.09 ? 58  TYR H O   1 
ATOM 434  C CB  . TYR A 1 58  ? 328.206 342.168 472.056 1.00 154.09 ? 58  TYR H CB  1 
ATOM 435  C CG  . TYR A 1 58  ? 327.117 343.206 472.014 1.00 154.09 ? 58  TYR H CG  1 
ATOM 436  C CD1 . TYR A 1 58  ? 327.383 344.531 472.324 1.00 154.09 ? 58  TYR H CD1 1 
ATOM 437  C CD2 . TYR A 1 58  ? 325.821 342.859 471.661 1.00 154.09 ? 58  TYR H CD2 1 
ATOM 438  C CE1 . TYR A 1 58  ? 326.386 345.481 472.289 1.00 154.09 ? 58  TYR H CE1 1 
ATOM 439  C CE2 . TYR A 1 58  ? 324.817 343.801 471.619 1.00 154.09 ? 58  TYR H CE2 1 
ATOM 440  C CZ  . TYR A 1 58  ? 325.106 345.110 471.933 1.00 154.09 ? 58  TYR H CZ  1 
ATOM 441  O OH  . TYR A 1 58  ? 324.107 346.052 471.893 1.00 154.09 ? 58  TYR H OH  1 
ATOM 442  N N   . THR A 1 59  ? 331.895 341.931 471.538 1.00 154.46 ? 59  THR H N   1 
ATOM 443  C CA  . THR A 1 59  ? 332.993 341.070 471.945 1.00 154.46 ? 59  THR H CA  1 
ATOM 444  C C   . THR A 1 59  ? 333.800 341.718 473.069 1.00 154.46 ? 59  THR H C   1 
ATOM 445  O O   . THR A 1 59  ? 333.687 342.912 473.346 1.00 154.46 ? 59  THR H O   1 
ATOM 446  C CB  . THR A 1 59  ? 333.895 340.752 470.756 1.00 154.46 ? 59  THR H CB  1 
ATOM 447  O OG1 . THR A 1 59  ? 334.655 341.915 470.408 1.00 154.46 ? 59  THR H OG1 1 
ATOM 448  C CG2 . THR A 1 59  ? 333.058 340.324 469.561 1.00 154.46 ? 59  THR H CG2 1 
ATOM 449  N N   . THR A 1 60  ? 334.610 340.901 473.741 1.00 157.33 ? 60  THR H N   1 
ATOM 450  C CA  . THR A 1 60  ? 335.451 341.344 474.843 1.00 157.33 ? 60  THR H CA  1 
ATOM 451  C C   . THR A 1 60  ? 336.895 340.927 474.603 1.00 157.33 ? 60  THR H C   1 
ATOM 452  O O   . THR A 1 60  ? 337.164 339.929 473.930 1.00 157.33 ? 60  THR H O   1 
ATOM 453  C CB  . THR A 1 60  ? 334.984 340.764 476.181 1.00 157.33 ? 60  THR H CB  1 
ATOM 454  O OG1 . THR A 1 60  ? 335.025 339.335 476.121 1.00 157.33 ? 60  THR H OG1 1 
ATOM 455  C CG2 . THR A 1 60  ? 333.574 341.212 476.510 1.00 157.33 ? 60  THR H CG2 1 
ATOM 456  N N   . GLU A 1 61  ? 337.826 341.710 475.152 1.00 157.27 ? 61  GLU H N   1 
ATOM 457  C CA  . GLU A 1 61  ? 339.257 341.393 475.143 1.00 157.27 ? 61  GLU H CA  1 
ATOM 458  C C   . GLU A 1 61  ? 339.839 341.763 476.502 1.00 157.27 ? 61  GLU H C   1 
ATOM 459  O O   . GLU A 1 61  ? 340.056 342.943 476.786 1.00 157.27 ? 61  GLU H O   1 
ATOM 460  C CB  . GLU A 1 61  ? 340.002 342.122 474.026 1.00 157.27 ? 61  GLU H CB  1 
ATOM 461  C CG  . GLU A 1 61  ? 339.745 341.597 472.629 1.00 157.27 ? 61  GLU H CG  1 
ATOM 462  C CD  . GLU A 1 61  ? 338.532 342.218 471.984 1.00 157.27 ? 61  GLU H CD  1 
ATOM 463  O OE1 . GLU A 1 61  ? 337.962 343.160 472.567 1.00 157.27 ? 61  GLU H OE1 1 
ATOM 464  O OE2 . GLU A 1 61  ? 338.134 341.750 470.902 1.00 157.27 ? 61  GLU H OE2 1 
ATOM 465  N N   . TYR A 1 62  ? 340.101 340.757 477.332 1.00 162.14 ? 62  TYR H N   1 
ATOM 466  C CA  . TYR A 1 62  ? 340.692 340.972 478.643 1.00 162.14 ? 62  TYR H CA  1 
ATOM 467  C C   . TYR A 1 62  ? 342.200 341.173 478.534 1.00 162.14 ? 62  TYR H C   1 
ATOM 468  O O   . TYR A 1 62  ? 342.787 341.150 477.450 1.00 162.14 ? 62  TYR H O   1 
ATOM 469  C CB  . TYR A 1 62  ? 340.406 339.791 479.563 1.00 162.14 ? 62  TYR H CB  1 
ATOM 470  C CG  . TYR A 1 62  ? 338.954 339.427 479.651 1.00 162.14 ? 62  TYR H CG  1 
ATOM 471  C CD1 . TYR A 1 62  ? 338.096 340.138 480.470 1.00 162.14 ? 62  TYR H CD1 1 
ATOM 472  C CD2 . TYR A 1 62  ? 338.440 338.371 478.917 1.00 162.14 ? 62  TYR H CD2 1 
ATOM 473  C CE1 . TYR A 1 62  ? 336.765 339.810 480.557 1.00 162.14 ? 62  TYR H CE1 1 
ATOM 474  C CE2 . TYR A 1 62  ? 337.110 338.034 478.994 1.00 162.14 ? 62  TYR H CE2 1 
ATOM 475  C CZ  . TYR A 1 62  ? 336.277 338.757 479.816 1.00 162.14 ? 62  TYR H CZ  1 
ATOM 476  O OH  . TYR A 1 62  ? 334.945 338.427 479.900 1.00 162.14 ? 62  TYR H OH  1 
ATOM 477  N N   . SER A 1 63  ? 342.830 341.361 479.688 1.00 164.21 ? 63  SER H N   1 
ATOM 478  C CA  . SER A 1 63  ? 344.281 341.424 479.767 1.00 164.21 ? 63  SER H CA  1 
ATOM 479  C C   . SER A 1 63  ? 344.838 340.003 479.827 1.00 164.21 ? 63  SER H C   1 
ATOM 480  O O   . SER A 1 63  ? 344.105 339.016 479.730 1.00 164.21 ? 63  SER H O   1 
ATOM 481  C CB  . SER A 1 63  ? 344.709 342.265 480.965 1.00 164.21 ? 63  SER H CB  1 
ATOM 482  O OG  . SER A 1 63  ? 346.027 341.946 481.366 1.00 164.21 ? 63  SER H OG  1 
ATOM 483  N N   . ALA A 1 64  ? 346.152 339.881 479.994 1.00 168.44 ? 64  ALA H N   1 
ATOM 484  C CA  . ALA A 1 64  ? 346.788 338.570 479.995 1.00 168.44 ? 64  ALA H CA  1 
ATOM 485  C C   . ALA A 1 64  ? 346.873 337.966 481.389 1.00 168.44 ? 64  ALA H C   1 
ATOM 486  O O   . ALA A 1 64  ? 346.849 336.739 481.534 1.00 168.44 ? 64  ALA H O   1 
ATOM 487  C CB  . ALA A 1 64  ? 348.189 338.662 479.386 1.00 168.44 ? 64  ALA H CB  1 
ATOM 488  N N   . SER A 1 65  ? 346.978 338.799 482.422 1.00 167.32 ? 65  SER H N   1 
ATOM 489  C CA  . SER A 1 65  ? 347.145 338.278 483.771 1.00 167.32 ? 65  SER H CA  1 
ATOM 490  C C   . SER A 1 65  ? 345.814 337.963 484.440 1.00 167.32 ? 65  SER H C   1 
ATOM 491  O O   . SER A 1 65  ? 345.769 337.137 485.357 1.00 167.32 ? 65  SER H O   1 
ATOM 492  C CB  . SER A 1 65  ? 347.938 339.275 484.617 1.00 167.32 ? 65  SER H CB  1 
ATOM 493  O OG  . SER A 1 65  ? 349.193 339.566 484.027 1.00 167.32 ? 65  SER H OG  1 
ATOM 494  N N   . VAL A 1 66  ? 344.726 338.592 484.001 1.00 170.49 ? 66  VAL H N   1 
ATOM 495  C CA  . VAL A 1 66  ? 343.445 338.496 484.687 1.00 170.49 ? 66  VAL H CA  1 
ATOM 496  C C   . VAL A 1 66  ? 342.386 337.808 483.837 1.00 170.49 ? 66  VAL H C   1 
ATOM 497  O O   . VAL A 1 66  ? 341.190 337.960 484.106 1.00 170.49 ? 66  VAL H O   1 
ATOM 498  C CB  . VAL A 1 66  ? 342.959 339.879 485.142 1.00 170.49 ? 66  VAL H CB  1 
ATOM 499  C CG1 . VAL A 1 66  ? 343.866 340.413 486.229 1.00 170.49 ? 66  VAL H CG1 1 
ATOM 500  C CG2 . VAL A 1 66  ? 342.925 340.831 483.967 1.00 170.49 ? 66  VAL H CG2 1 
ATOM 501  N N   . LYS A 1 67  ? 342.790 337.053 482.819 1.00 163.93 ? 67  LYS H N   1 
ATOM 502  C CA  . LYS A 1 67  ? 341.828 336.368 481.965 1.00 163.93 ? 67  LYS H CA  1 
ATOM 503  C C   . LYS A 1 67  ? 341.228 335.179 482.704 1.00 163.93 ? 67  LYS H C   1 
ATOM 504  O O   . LYS A 1 67  ? 341.930 334.479 483.440 1.00 163.93 ? 67  LYS H O   1 
ATOM 505  C CB  . LYS A 1 67  ? 342.493 335.909 480.672 1.00 163.93 ? 67  LYS H CB  1 
ATOM 506  C CG  . LYS A 1 67  ? 341.511 335.442 479.608 1.00 163.93 ? 67  LYS H CG  1 
ATOM 507  C CD  . LYS A 1 67  ? 342.218 335.023 478.333 1.00 163.93 ? 67  LYS H CD  1 
ATOM 508  C CE  . LYS A 1 67  ? 341.459 333.916 477.613 1.00 163.93 ? 67  LYS H CE  1 
ATOM 509  N NZ  . LYS A 1 67  ? 340.533 334.451 476.578 1.00 163.93 ? 67  LYS H NZ  1 
ATOM 510  N N   . GLY A 1 68  ? 339.928 334.960 482.514 1.00 174.12 ? 68  GLY H N   1 
ATOM 511  C CA  . GLY A 1 68  ? 339.230 333.813 483.044 1.00 174.12 ? 68  GLY H CA  1 
ATOM 512  C C   . GLY A 1 68  ? 338.578 334.035 484.391 1.00 174.12 ? 68  GLY H C   1 
ATOM 513  O O   . GLY A 1 68  ? 337.425 333.630 484.580 1.00 174.12 ? 68  GLY H O   1 
ATOM 514  N N   . ARG A 1 69  ? 339.278 334.670 485.324 1.00 182.44 ? 69  ARG H N   1 
ATOM 515  C CA  . ARG A 1 69  ? 338.741 334.872 486.660 1.00 182.44 ? 69  ARG H CA  1 
ATOM 516  C C   . ARG A 1 69  ? 337.634 335.915 486.680 1.00 182.44 ? 69  ARG H C   1 
ATOM 517  O O   . ARG A 1 69  ? 336.808 335.925 487.599 1.00 182.44 ? 69  ARG H O   1 
ATOM 518  C CB  . ARG A 1 69  ? 339.864 335.275 487.616 1.00 182.44 ? 69  ARG H CB  1 
ATOM 519  C CG  . ARG A 1 69  ? 341.014 334.289 487.643 1.00 182.44 ? 69  ARG H CG  1 
ATOM 520  C CD  . ARG A 1 69  ? 341.662 334.231 489.011 1.00 182.44 ? 69  ARG H CD  1 
ATOM 521  N NE  . ARG A 1 69  ? 342.619 335.312 489.213 1.00 182.44 ? 69  ARG H NE  1 
ATOM 522  C CZ  . ARG A 1 69  ? 342.388 336.380 489.966 1.00 182.44 ? 69  ARG H CZ  1 
ATOM 523  N NH1 . ARG A 1 69  ? 341.226 336.514 490.589 1.00 182.44 ? 69  ARG H NH1 1 
ATOM 524  N NH2 . ARG A 1 69  ? 343.316 337.316 490.097 1.00 182.44 ? 69  ARG H NH2 1 
ATOM 525  N N   . PHE A 1 70  ? 337.600 336.797 485.690 1.00 180.44 ? 70  PHE H N   1 
ATOM 526  C CA  . PHE A 1 70  ? 336.577 337.826 485.602 1.00 180.44 ? 70  PHE H CA  1 
ATOM 527  C C   . PHE A 1 70  ? 335.754 337.620 484.338 1.00 180.44 ? 70  PHE H C   1 
ATOM 528  O O   . PHE A 1 70  ? 336.088 336.801 483.478 1.00 180.44 ? 70  PHE H O   1 
ATOM 529  C CB  . PHE A 1 70  ? 337.202 339.224 485.605 1.00 180.44 ? 70  PHE H CB  1 
ATOM 530  C CG  . PHE A 1 70  ? 338.154 339.459 486.740 1.00 180.44 ? 70  PHE H CG  1 
ATOM 531  C CD1 . PHE A 1 70  ? 337.864 339.005 488.021 1.00 180.44 ? 70  PHE H CD1 1 
ATOM 532  C CD2 . PHE A 1 70  ? 339.353 340.113 486.521 1.00 180.44 ? 70  PHE H CD2 1 
ATOM 533  C CE1 . PHE A 1 70  ? 338.751 339.201 489.058 1.00 180.44 ? 70  PHE H CE1 1 
ATOM 534  C CE2 . PHE A 1 70  ? 340.242 340.322 487.559 1.00 180.44 ? 70  PHE H CE2 1 
ATOM 535  C CZ  . PHE A 1 70  ? 339.938 339.866 488.830 1.00 180.44 ? 70  PHE H CZ  1 
ATOM 536  N N   . THR A 1 71  ? 334.661 338.370 484.238 1.00 181.73 ? 71  THR H N   1 
ATOM 537  C CA  . THR A 1 71  ? 333.781 338.278 483.078 1.00 181.73 ? 71  THR H CA  1 
ATOM 538  C C   . THR A 1 71  ? 333.054 339.601 482.916 1.00 181.73 ? 71  THR H C   1 
ATOM 539  O O   . THR A 1 71  ? 332.372 340.053 483.841 1.00 181.73 ? 71  THR H O   1 
ATOM 540  C CB  . THR A 1 71  ? 332.783 337.126 483.228 1.00 181.73 ? 71  THR H CB  1 
ATOM 541  O OG1 . THR A 1 71  ? 333.468 335.880 483.060 1.00 181.73 ? 71  THR H OG1 1 
ATOM 542  C CG2 . THR A 1 71  ? 331.678 337.223 482.188 1.00 181.73 ? 71  THR H CG2 1 
ATOM 543  N N   . ILE A 1 72  ? 333.202 340.215 481.746 1.00 175.78 ? 72  ILE H N   1 
ATOM 544  C CA  . ILE A 1 72  ? 332.515 341.451 481.401 1.00 175.78 ? 72  ILE H CA  1 
ATOM 545  C C   . ILE A 1 72  ? 331.254 341.088 480.638 1.00 175.78 ? 72  ILE H C   1 
ATOM 546  O O   . ILE A 1 72  ? 331.319 340.399 479.614 1.00 175.78 ? 72  ILE H O   1 
ATOM 547  C CB  . ILE A 1 72  ? 333.412 342.375 480.564 1.00 175.78 ? 72  ILE H CB  1 
ATOM 548  C CG1 . ILE A 1 72  ? 334.674 342.719 481.349 1.00 175.78 ? 72  ILE H CG1 1 
ATOM 549  C CG2 . ILE A 1 72  ? 332.648 343.620 480.142 1.00 175.78 ? 72  ILE H CG2 1 
ATOM 550  C CD1 . ILE A 1 72  ? 334.435 343.663 482.481 1.00 175.78 ? 72  ILE H CD1 1 
ATOM 551  N N   . SER A 1 73  ? 330.111 341.545 481.134 1.00 181.25 ? 73  SER H N   1 
ATOM 552  C CA  . SER A 1 73  ? 328.843 341.261 480.479 1.00 181.25 ? 73  SER H CA  1 
ATOM 553  C C   . SER A 1 73  ? 327.942 342.475 480.623 1.00 181.25 ? 73  SER H C   1 
ATOM 554  O O   . SER A 1 73  ? 328.013 343.216 481.604 1.00 181.25 ? 73  SER H O   1 
ATOM 555  C CB  . SER A 1 73  ? 328.174 340.017 481.064 1.00 181.25 ? 73  SER H CB  1 
ATOM 556  O OG  . SER A 1 73  ? 326.910 339.800 480.463 1.00 181.25 ? 73  SER H OG  1 
ATOM 557  N N   . ARG A 1 74  ? 327.080 342.657 479.631 1.00 185.17 ? 74  ARG H N   1 
ATOM 558  C CA  . ARG A 1 74  ? 326.153 343.772 479.607 1.00 185.17 ? 74  ARG H CA  1 
ATOM 559  C C   . ARG A 1 74  ? 324.730 343.244 479.639 1.00 185.17 ? 74  ARG H C   1 
ATOM 560  O O   . ARG A 1 74  ? 324.469 342.067 479.379 1.00 185.17 ? 74  ARG H O   1 
ATOM 561  C CB  . ARG A 1 74  ? 326.352 344.648 478.364 1.00 185.17 ? 74  ARG H CB  1 
ATOM 562  C CG  . ARG A 1 74  ? 325.985 343.957 477.064 1.00 185.17 ? 74  ARG H CG  1 
ATOM 563  C CD  . ARG A 1 74  ? 326.198 344.872 475.874 1.00 185.17 ? 74  ARG H CD  1 
ATOM 564  N NE  . ARG A 1 74  ? 325.303 346.023 475.898 1.00 185.17 ? 74  ARG H NE  1 
ATOM 565  C CZ  . ARG A 1 74  ? 324.080 346.026 475.380 1.00 185.17 ? 74  ARG H CZ  1 
ATOM 566  N NH1 . ARG A 1 74  ? 323.604 344.935 474.800 1.00 185.17 ? 74  ARG H NH1 1 
ATOM 567  N NH2 . ARG A 1 74  ? 323.331 347.118 475.442 1.00 185.17 ? 74  ARG H NH2 1 
ATOM 568  N N   . ASP A 1 75  ? 323.811 344.135 479.976 1.00 203.53 ? 75  ASP H N   1 
ATOM 569  C CA  . ASP A 1 75  ? 322.390 343.851 479.920 1.00 203.53 ? 75  ASP H CA  1 
ATOM 570  C C   . ASP A 1 75  ? 321.856 344.454 478.629 1.00 203.53 ? 75  ASP H C   1 
ATOM 571  O O   . ASP A 1 75  ? 322.305 345.521 478.201 1.00 203.53 ? 75  ASP H O   1 
ATOM 572  C CB  . ASP A 1 75  ? 321.678 344.444 481.140 1.00 203.53 ? 75  ASP H CB  1 
ATOM 573  C CG  . ASP A 1 75  ? 320.202 344.074 481.222 1.00 203.53 ? 75  ASP H CG  1 
ATOM 574  O OD1 . ASP A 1 75  ? 319.693 343.297 480.389 1.00 203.53 ? 75  ASP H OD1 1 
ATOM 575  O OD2 . ASP A 1 75  ? 319.539 344.577 482.151 1.00 203.53 ? 75  ASP H OD2 1 
ATOM 576  N N   . ASN A 1 76  ? 320.911 343.759 477.999 1.00 209.75 ? 76  ASN H N   1 
ATOM 577  C CA  . ASN A 1 76  ? 320.343 344.289 476.767 1.00 209.75 ? 76  ASN H CA  1 
ATOM 578  C C   . ASN A 1 76  ? 319.237 345.298 477.040 1.00 209.75 ? 76  ASN H C   1 
ATOM 579  O O   . ASN A 1 76  ? 318.961 346.152 476.190 1.00 209.75 ? 76  ASN H O   1 
ATOM 580  C CB  . ASN A 1 76  ? 319.818 343.153 475.887 1.00 209.75 ? 76  ASN H CB  1 
ATOM 581  C CG  . ASN A 1 76  ? 319.040 342.122 476.667 1.00 209.75 ? 76  ASN H CG  1 
ATOM 582  O OD1 . ASN A 1 76  ? 318.774 342.293 477.853 1.00 209.75 ? 76  ASN H OD1 1 
ATOM 583  N ND2 . ASN A 1 76  ? 318.664 341.040 476.000 1.00 209.75 ? 76  ASN H ND2 1 
ATOM 584  N N   . SER A 1 77  ? 318.612 345.233 478.215 1.00 208.81 ? 77  SER H N   1 
ATOM 585  C CA  . SER A 1 77  ? 317.428 346.045 478.467 1.00 208.81 ? 77  SER H CA  1 
ATOM 586  C C   . SER A 1 77  ? 317.789 347.500 478.752 1.00 208.81 ? 77  SER H C   1 
ATOM 587  O O   . SER A 1 77  ? 317.424 348.399 477.988 1.00 208.81 ? 77  SER H O   1 
ATOM 588  C CB  . SER A 1 77  ? 316.629 345.449 479.628 1.00 208.81 ? 77  SER H CB  1 
ATOM 589  O OG  . SER A 1 77  ? 317.396 345.448 480.817 1.00 208.81 ? 77  SER H OG  1 
ATOM 590  N N   . GLN A 1 78  ? 318.519 347.750 479.834 1.00 203.48 ? 78  GLN H N   1 
ATOM 591  C CA  . GLN A 1 78  ? 318.861 349.108 480.228 1.00 203.48 ? 78  GLN H CA  1 
ATOM 592  C C   . GLN A 1 78  ? 320.346 349.368 480.026 1.00 203.48 ? 78  GLN H C   1 
ATOM 593  O O   . GLN A 1 78  ? 321.155 348.451 479.865 1.00 203.48 ? 78  GLN H O   1 
ATOM 594  C CB  . GLN A 1 78  ? 318.479 349.380 481.688 1.00 203.48 ? 78  GLN H CB  1 
ATOM 595  C CG  . GLN A 1 78  ? 317.053 349.030 482.052 1.00 203.48 ? 78  GLN H CG  1 
ATOM 596  C CD  . GLN A 1 78  ? 316.963 347.765 482.870 1.00 203.48 ? 78  GLN H CD  1 
ATOM 597  O OE1 . GLN A 1 78  ? 317.733 346.828 482.665 1.00 203.48 ? 78  GLN H OE1 1 
ATOM 598  N NE2 . GLN A 1 78  ? 316.026 347.729 483.808 1.00 203.48 ? 78  GLN H NE2 1 
ATOM 599  N N   . SER A 1 79  ? 320.695 350.653 480.053 1.00 196.58 ? 79  SER H N   1 
ATOM 600  C CA  . SER A 1 79  ? 322.081 351.099 479.929 1.00 196.58 ? 79  SER H CA  1 
ATOM 601  C C   . SER A 1 79  ? 322.773 350.839 481.259 1.00 196.58 ? 79  SER H C   1 
ATOM 602  O O   . SER A 1 79  ? 322.939 351.734 482.089 1.00 196.58 ? 79  SER H O   1 
ATOM 603  C CB  . SER A 1 79  ? 322.137 352.569 479.539 1.00 196.58 ? 79  SER H CB  1 
ATOM 604  O OG  . SER A 1 79  ? 321.437 352.796 478.329 1.00 196.58 ? 79  SER H OG  1 
ATOM 605  N N   . ILE A 1 80  ? 323.185 349.590 481.463 1.00 192.82 ? 80  ILE H N   1 
ATOM 606  C CA  . ILE A 1 80  ? 323.816 349.170 482.705 1.00 192.82 ? 80  ILE H CA  1 
ATOM 607  C C   . ILE A 1 80  ? 324.885 348.148 482.348 1.00 192.82 ? 80  ILE H C   1 
ATOM 608  O O   . ILE A 1 80  ? 324.857 347.534 481.279 1.00 192.82 ? 80  ILE H O   1 
ATOM 609  C CB  . ILE A 1 80  ? 322.773 348.613 483.710 1.00 192.82 ? 80  ILE H CB  1 
ATOM 610  C CG1 . ILE A 1 80  ? 323.162 348.945 485.150 1.00 192.82 ? 80  ILE H CG1 1 
ATOM 611  C CG2 . ILE A 1 80  ? 322.565 347.114 483.547 1.00 192.82 ? 80  ILE H CG2 1 
ATOM 612  C CD1 . ILE A 1 80  ? 322.068 348.635 486.148 1.00 192.82 ? 80  ILE H CD1 1 
ATOM 613  N N   . LEU A 1 81  ? 325.859 347.995 483.238 1.00 191.05 ? 81  LEU H N   1 
ATOM 614  C CA  . LEU A 1 81  ? 327.001 347.130 482.992 1.00 191.05 ? 81  LEU H CA  1 
ATOM 615  C C   . LEU A 1 81  ? 327.277 346.281 484.219 1.00 191.05 ? 81  LEU H C   1 
ATOM 616  O O   . LEU A 1 81  ? 327.103 346.738 485.352 1.00 191.05 ? 81  LEU H O   1 
ATOM 617  C CB  . LEU A 1 81  ? 328.244 347.939 482.643 1.00 191.05 ? 81  LEU H CB  1 
ATOM 618  C CG  . LEU A 1 81  ? 329.334 347.186 481.883 1.00 191.05 ? 81  LEU H CG  1 
ATOM 619  C CD1 . LEU A 1 81  ? 328.747 346.363 480.746 1.00 191.05 ? 81  LEU H CD1 1 
ATOM 620  C CD2 . LEU A 1 81  ? 330.364 348.160 481.366 1.00 191.05 ? 81  LEU H CD2 1 
ATOM 621  N N   . TYR A 1 82  ? 327.706 345.046 483.990 1.00 189.99 ? 82  TYR H N   1 
ATOM 622  C CA  . TYR A 1 82  ? 328.032 344.125 485.065 1.00 189.99 ? 82  TYR H CA  1 
ATOM 623  C C   . TYR A 1 82  ? 329.516 343.800 485.033 1.00 189.99 ? 82  TYR H C   1 
ATOM 624  O O   . TYR A 1 82  ? 330.199 343.975 484.022 1.00 189.99 ? 82  TYR H O   1 
ATOM 625  C CB  . TYR A 1 82  ? 327.217 342.832 484.964 1.00 189.99 ? 82  TYR H CB  1 
ATOM 626  C CG  . TYR A 1 82  ? 325.726 343.040 484.928 1.00 189.99 ? 82  TYR H CG  1 
ATOM 627  C CD1 . TYR A 1 82  ? 325.123 344.048 485.673 1.00 189.99 ? 82  TYR H CD1 1 
ATOM 628  C CD2 . TYR A 1 82  ? 324.917 342.228 484.149 1.00 189.99 ? 82  TYR H CD2 1 
ATOM 629  C CE1 . TYR A 1 82  ? 323.756 344.242 485.637 1.00 189.99 ? 82  TYR H CE1 1 
ATOM 630  C CE2 . TYR A 1 82  ? 323.549 342.412 484.109 1.00 189.99 ? 82  TYR H CE2 1 
ATOM 631  C CZ  . TYR A 1 82  ? 322.975 343.420 484.854 1.00 189.99 ? 82  TYR H CZ  1 
ATOM 632  O OH  . TYR A 1 82  ? 321.613 343.602 484.813 1.00 189.99 ? 82  TYR H OH  1 
ATOM 633  N N   . LEU A 1 83  ? 330.008 343.316 486.167 1.00 192.48 ? 83  LEU H N   1 
ATOM 634  C CA  . LEU A 1 83  ? 331.382 342.835 486.263 1.00 192.48 ? 83  LEU H CA  1 
ATOM 635  C C   . LEU A 1 83  ? 331.389 341.685 487.255 1.00 192.48 ? 83  LEU H C   1 
ATOM 636  O O   . LEU A 1 83  ? 331.239 341.907 488.460 1.00 192.48 ? 83  LEU H O   1 
ATOM 637  C CB  . LEU A 1 83  ? 332.328 343.949 486.688 1.00 192.48 ? 83  LEU H CB  1 
ATOM 638  C CG  . LEU A 1 83  ? 333.804 343.555 486.740 1.00 192.48 ? 83  LEU H CG  1 
ATOM 639  C CD1 . LEU A 1 83  ? 334.647 344.589 486.074 1.00 192.48 ? 83  LEU H CD1 1 
ATOM 640  C CD2 . LEU A 1 83  ? 334.263 343.420 488.176 1.00 192.48 ? 83  LEU H CD2 1 
ATOM 641  N N   . GLN A 1 84  ? 331.567 340.472 486.754 1.00 196.03 ? 84  GLN H N   1 
ATOM 642  C CA  . GLN A 1 84  ? 331.546 339.280 487.584 1.00 196.03 ? 84  GLN H CA  1 
ATOM 643  C C   . GLN A 1 84  ? 332.967 338.972 488.037 1.00 196.03 ? 84  GLN H C   1 
ATOM 644  O O   . GLN A 1 84  ? 333.893 338.948 487.220 1.00 196.03 ? 84  GLN H O   1 
ATOM 645  C CB  . GLN A 1 84  ? 330.944 338.101 486.824 1.00 196.03 ? 84  GLN H CB  1 
ATOM 646  C CG  . GLN A 1 84  ? 330.789 336.862 487.669 1.00 196.03 ? 84  GLN H CG  1 
ATOM 647  C CD  . GLN A 1 84  ? 329.999 337.130 488.930 1.00 196.03 ? 84  GLN H CD  1 
ATOM 648  O OE1 . GLN A 1 84  ? 328.889 337.655 488.878 1.00 196.03 ? 84  GLN H OE1 1 
ATOM 649  N NE2 . GLN A 1 84  ? 330.574 336.783 490.074 1.00 196.03 ? 84  GLN H NE2 1 
ATOM 650  N N   . MET A 1 85  ? 333.138 338.758 489.336 1.00 200.83 ? 85  MET H N   1 
ATOM 651  C CA  . MET A 1 85  ? 334.414 338.369 489.913 1.00 200.83 ? 85  MET H CA  1 
ATOM 652  C C   . MET A 1 85  ? 334.315 336.945 490.438 1.00 200.83 ? 85  MET H C   1 
ATOM 653  O O   . MET A 1 85  ? 333.300 336.547 491.013 1.00 200.83 ? 85  MET H O   1 
ATOM 654  C CB  . MET A 1 85  ? 334.809 339.314 491.049 1.00 200.83 ? 85  MET H CB  1 
ATOM 655  C CG  . MET A 1 85  ? 334.586 340.778 490.732 1.00 200.83 ? 85  MET H CG  1 
ATOM 656  S SD  . MET A 1 85  ? 335.528 341.933 491.746 1.00 200.83 ? 85  MET H SD  1 
ATOM 657  C CE  . MET A 1 85  ? 337.204 341.425 491.407 1.00 200.83 ? 85  MET H CE  1 
ATOM 658  N N   . ASN A 1 86  ? 335.376 336.174 490.236 1.00 192.43 ? 86  ASN H N   1 
ATOM 659  C CA  . ASN A 1 86  ? 335.402 334.804 490.719 1.00 192.43 ? 86  ASN H CA  1 
ATOM 660  C C   . ASN A 1 86  ? 336.788 334.467 491.240 1.00 192.43 ? 86  ASN H C   1 
ATOM 661  O O   . ASN A 1 86  ? 337.795 334.745 490.581 1.00 192.43 ? 86  ASN H O   1 
ATOM 662  C CB  . ASN A 1 86  ? 335.004 333.814 489.625 1.00 192.43 ? 86  ASN H CB  1 
ATOM 663  C CG  . ASN A 1 86  ? 333.527 333.845 489.329 1.00 192.43 ? 86  ASN H CG  1 
ATOM 664  O OD1 . ASN A 1 86  ? 333.114 334.070 488.193 1.00 192.43 ? 86  ASN H OD1 1 
ATOM 665  N ND2 . ASN A 1 86  ? 332.717 333.618 490.351 1.00 192.43 ? 86  ASN H ND2 1 
ATOM 666  N N   . ALA A 1 87  ? 336.810 333.863 492.434 1.00 194.82 ? 87  ALA H N   1 
ATOM 667  C CA  . ALA A 1 87  ? 338.013 333.367 493.110 1.00 194.82 ? 87  ALA H CA  1 
ATOM 668  C C   . ALA A 1 87  ? 339.043 334.480 493.309 1.00 194.82 ? 87  ALA H C   1 
ATOM 669  O O   . ALA A 1 87  ? 340.139 334.464 492.744 1.00 194.82 ? 87  ALA H O   1 
ATOM 670  C CB  . ALA A 1 87  ? 338.616 332.171 492.364 1.00 194.82 ? 87  ALA H CB  1 
ATOM 671  N N   . LEU A 1 88  ? 338.656 335.464 494.117 1.00 198.07 ? 88  LEU H N   1 
ATOM 672  C CA  . LEU A 1 88  ? 339.523 336.600 494.392 1.00 198.07 ? 88  LEU H CA  1 
ATOM 673  C C   . LEU A 1 88  ? 340.728 336.175 495.219 1.00 198.07 ? 88  LEU H C   1 
ATOM 674  O O   . LEU A 1 88  ? 340.722 335.126 495.868 1.00 198.07 ? 88  LEU H O   1 
ATOM 675  C CB  . LEU A 1 88  ? 338.760 337.698 495.133 1.00 198.07 ? 88  LEU H CB  1 
ATOM 676  C CG  . LEU A 1 88  ? 337.417 338.195 494.597 1.00 198.07 ? 88  LEU H CG  1 
ATOM 677  C CD1 . LEU A 1 88  ? 336.256 337.508 495.284 1.00 198.07 ? 88  LEU H CD1 1 
ATOM 678  C CD2 . LEU A 1 88  ? 337.317 339.699 494.774 1.00 198.07 ? 88  LEU H CD2 1 
ATOM 679  N N   . ARG A 1 89  ? 341.768 336.991 495.183 1.00 201.56 ? 89  ARG H N   1 
ATOM 680  C CA  . ARG A 1 89  ? 342.949 336.792 496.001 1.00 201.56 ? 89  ARG H CA  1 
ATOM 681  C C   . ARG A 1 89  ? 343.125 337.987 496.932 1.00 201.56 ? 89  ARG H C   1 
ATOM 682  O O   . ARG A 1 89  ? 342.319 338.920 496.949 1.00 201.56 ? 89  ARG H O   1 
ATOM 683  C CB  . ARG A 1 89  ? 344.182 336.575 495.124 1.00 201.56 ? 89  ARG H CB  1 
ATOM 684  C CG  . ARG A 1 89  ? 345.062 335.415 495.572 1.00 201.56 ? 89  ARG H CG  1 
ATOM 685  C CD  . ARG A 1 89  ? 346.143 335.072 494.550 1.00 201.56 ? 89  ARG H CD  1 
ATOM 686  N NE  . ARG A 1 89  ? 345.612 334.661 493.251 1.00 201.56 ? 89  ARG H NE  1 
ATOM 687  C CZ  . ARG A 1 89  ? 345.613 335.423 492.161 1.00 201.56 ? 89  ARG H CZ  1 
ATOM 688  N NH1 . ARG A 1 89  ? 346.109 336.648 492.209 1.00 201.56 ? 89  ARG H NH1 1 
ATOM 689  N NH2 . ARG A 1 89  ? 345.112 334.961 491.025 1.00 201.56 ? 89  ARG H NH2 1 
ATOM 690  N N   . ALA A 1 90  ? 344.197 337.950 497.719 1.00 200.93 ? 90  ALA H N   1 
ATOM 691  C CA  . ALA A 1 90  ? 344.442 339.011 498.684 1.00 200.93 ? 90  ALA H CA  1 
ATOM 692  C C   . ALA A 1 90  ? 345.019 340.271 498.050 1.00 200.93 ? 90  ALA H C   1 
ATOM 693  O O   . ALA A 1 90  ? 345.031 341.322 498.701 1.00 200.93 ? 90  ALA H O   1 
ATOM 694  C CB  . ALA A 1 90  ? 345.375 338.514 499.788 1.00 200.93 ? 90  ALA H CB  1 
ATOM 695  N N   . GLU A 1 91  ? 345.492 340.198 496.806 1.00 204.42 ? 91  GLU H N   1 
ATOM 696  C CA  . GLU A 1 91  ? 346.160 341.324 496.163 1.00 204.42 ? 91  GLU H CA  1 
ATOM 697  C C   . GLU A 1 91  ? 345.255 342.119 495.232 1.00 204.42 ? 91  GLU H C   1 
ATOM 698  O O   . GLU A 1 91  ? 345.736 343.050 494.578 1.00 204.42 ? 91  GLU H O   1 
ATOM 699  C CB  . GLU A 1 91  ? 347.381 340.841 495.378 1.00 204.42 ? 91  GLU H CB  1 
ATOM 700  C CG  . GLU A 1 91  ? 347.041 339.936 494.218 1.00 204.42 ? 91  GLU H CG  1 
ATOM 701  C CD  . GLU A 1 91  ? 347.319 338.488 494.529 1.00 204.42 ? 91  GLU H CD  1 
ATOM 702  O OE1 . GLU A 1 91  ? 347.784 337.766 493.623 1.00 204.42 ? 91  GLU H OE1 1 
ATOM 703  O OE2 . GLU A 1 91  ? 347.083 338.074 495.681 1.00 204.42 ? 91  GLU H OE2 1 
ATOM 704  N N   . ASP A 1 92  ? 343.971 341.783 495.146 1.00 198.91 ? 92  ASP H N   1 
ATOM 705  C CA  . ASP A 1 92  ? 343.036 342.554 494.340 1.00 198.91 ? 92  ASP H CA  1 
ATOM 706  C C   . ASP A 1 92  ? 342.371 343.676 495.125 1.00 198.91 ? 92  ASP H C   1 
ATOM 707  O O   . ASP A 1 92  ? 341.293 344.136 494.737 1.00 198.91 ? 92  ASP H O   1 
ATOM 708  C CB  . ASP A 1 92  ? 341.977 341.635 493.732 1.00 198.91 ? 92  ASP H CB  1 
ATOM 709  C CG  . ASP A 1 92  ? 342.453 340.976 492.456 1.00 198.91 ? 92  ASP H CG  1 
ATOM 710  O OD1 . ASP A 1 92  ? 343.639 341.147 492.110 1.00 198.91 ? 92  ASP H OD1 1 
ATOM 711  O OD2 . ASP A 1 92  ? 341.644 340.293 491.796 1.00 198.91 ? 92  ASP H OD2 1 
ATOM 712  N N   . SER A 1 93  ? 342.988 344.124 496.216 1.00 198.93 ? 93  SER H N   1 
ATOM 713  C CA  . SER A 1 93  ? 342.485 345.256 496.983 1.00 198.93 ? 93  SER H CA  1 
ATOM 714  C C   . SER A 1 93  ? 342.794 346.534 496.217 1.00 198.93 ? 93  SER H C   1 
ATOM 715  O O   . SER A 1 93  ? 343.900 347.073 496.316 1.00 198.93 ? 93  SER H O   1 
ATOM 716  C CB  . SER A 1 93  ? 343.117 345.286 498.369 1.00 198.93 ? 93  SER H CB  1 
ATOM 717  O OG  . SER A 1 93  ? 344.501 345.567 498.279 1.00 198.93 ? 93  SER H OG  1 
ATOM 718  N N   . ALA A 1 94  ? 341.822 347.018 495.455 1.00 193.85 ? 94  ALA H N   1 
ATOM 719  C CA  . ALA A 1 94  ? 341.990 348.235 494.676 1.00 193.85 ? 94  ALA H CA  1 
ATOM 720  C C   . ALA A 1 94  ? 340.621 348.873 494.499 1.00 193.85 ? 94  ALA H C   1 
ATOM 721  O O   . ALA A 1 94  ? 339.603 348.339 494.947 1.00 193.85 ? 94  ALA H O   1 
ATOM 722  C CB  . ALA A 1 94  ? 342.656 347.938 493.332 1.00 193.85 ? 94  ALA H CB  1 
ATOM 723  N N   . THR A 1 95  ? 340.598 350.024 493.838 1.00 191.41 ? 95  THR H N   1 
ATOM 724  C CA  . THR A 1 95  ? 339.355 350.703 493.504 1.00 191.41 ? 95  THR H CA  1 
ATOM 725  C C   . THR A 1 95  ? 339.081 350.482 492.025 1.00 191.41 ? 95  THR H C   1 
ATOM 726  O O   . THR A 1 95  ? 340.017 350.303 491.240 1.00 191.41 ? 95  THR H O   1 
ATOM 727  C CB  . THR A 1 95  ? 339.417 352.190 493.852 1.00 191.41 ? 95  THR H CB  1 
ATOM 728  O OG1 . THR A 1 95  ? 338.159 352.806 493.552 1.00 191.41 ? 95  THR H OG1 1 
ATOM 729  C CG2 . THR A 1 95  ? 340.539 352.897 493.103 1.00 191.41 ? 95  THR H CG2 1 
ATOM 730  N N   . TYR A 1 96  ? 337.809 350.436 491.654 1.00 189.19 ? 96  TYR H N   1 
ATOM 731  C CA  . TYR A 1 96  ? 337.419 350.092 490.294 1.00 189.19 ? 96  TYR H CA  1 
ATOM 732  C C   . TYR A 1 96  ? 336.619 351.224 489.668 1.00 189.19 ? 96  TYR H C   1 
ATOM 733  O O   . TYR A 1 96  ? 335.632 351.688 490.247 1.00 189.19 ? 96  TYR H O   1 
ATOM 734  C CB  . TYR A 1 96  ? 336.620 348.791 490.281 1.00 189.19 ? 96  TYR H CB  1 
ATOM 735  C CG  . TYR A 1 96  ? 337.501 347.575 490.421 1.00 189.19 ? 96  TYR H CG  1 
ATOM 736  C CD1 . TYR A 1 96  ? 337.970 347.171 491.664 1.00 189.19 ? 96  TYR H CD1 1 
ATOM 737  C CD2 . TYR A 1 96  ? 337.880 346.842 489.309 1.00 189.19 ? 96  TYR H CD2 1 
ATOM 738  C CE1 . TYR A 1 96  ? 338.785 346.063 491.793 1.00 189.19 ? 96  TYR H CE1 1 
ATOM 739  C CE2 . TYR A 1 96  ? 338.692 345.733 489.429 1.00 189.19 ? 96  TYR H CE2 1 
ATOM 740  C CZ  . TYR A 1 96  ? 339.142 345.350 490.671 1.00 189.19 ? 96  TYR H CZ  1 
ATOM 741  O OH  . TYR A 1 96  ? 339.952 344.246 490.788 1.00 189.19 ? 96  TYR H OH  1 
ATOM 742  N N   . TYR A 1 97  ? 337.042 351.655 488.485 1.00 184.44 ? 97  TYR H N   1 
ATOM 743  C CA  . TYR A 1 97  ? 336.471 352.800 487.796 1.00 184.44 ? 97  TYR H CA  1 
ATOM 744  C C   . TYR A 1 97  ? 335.643 352.341 486.601 1.00 184.44 ? 97  TYR H C   1 
ATOM 745  O O   . TYR A 1 97  ? 335.534 351.152 486.310 1.00 184.44 ? 97  TYR H O   1 
ATOM 746  C CB  . TYR A 1 97  ? 337.578 353.756 487.357 1.00 184.44 ? 97  TYR H CB  1 
ATOM 747  C CG  . TYR A 1 97  ? 338.117 354.614 488.470 1.00 184.44 ? 97  TYR H CG  1 
ATOM 748  C CD1 . TYR A 1 97  ? 337.473 355.787 488.837 1.00 184.44 ? 97  TYR H CD1 1 
ATOM 749  C CD2 . TYR A 1 97  ? 339.272 354.257 489.149 1.00 184.44 ? 97  TYR H CD2 1 
ATOM 750  C CE1 . TYR A 1 97  ? 337.962 356.577 489.854 1.00 184.44 ? 97  TYR H CE1 1 
ATOM 751  C CE2 . TYR A 1 97  ? 339.769 355.043 490.167 1.00 184.44 ? 97  TYR H CE2 1 
ATOM 752  C CZ  . TYR A 1 97  ? 339.108 356.200 490.514 1.00 184.44 ? 97  TYR H CZ  1 
ATOM 753  O OH  . TYR A 1 97  ? 339.593 356.989 491.525 1.00 184.44 ? 97  TYR H OH  1 
ATOM 754  N N   . CYS A 1 98  ? 335.067 353.311 485.894 1.00 186.95 ? 98  CYS H N   1 
ATOM 755  C CA  . CYS A 1 98  ? 334.226 353.030 484.731 1.00 186.95 ? 98  CYS H CA  1 
ATOM 756  C C   . CYS A 1 98  ? 334.596 354.044 483.654 1.00 186.95 ? 98  CYS H C   1 
ATOM 757  O O   . CYS A 1 98  ? 334.287 355.228 483.792 1.00 186.95 ? 98  CYS H O   1 
ATOM 758  C CB  . CYS A 1 98  ? 332.749 353.120 485.084 1.00 186.95 ? 98  CYS H CB  1 
ATOM 759  S SG  . CYS A 1 98  ? 332.045 351.699 485.933 1.00 186.95 ? 98  CYS H SG  1 
ATOM 760  N N   . ALA A 1 99  ? 335.239 353.581 482.591 1.00 173.60 ? 99  ALA H N   1 
ATOM 761  C CA  . ALA A 1 99  ? 335.739 354.477 481.562 1.00 173.60 ? 99  ALA H CA  1 
ATOM 762  C C   . ALA A 1 99  ? 335.007 354.277 480.243 1.00 173.60 ? 99  ALA H C   1 
ATOM 763  O O   . ALA A 1 99  ? 334.556 353.179 479.915 1.00 173.60 ? 99  ALA H O   1 
ATOM 764  C CB  . ALA A 1 99  ? 337.239 354.272 481.352 1.00 173.60 ? 99  ALA H CB  1 
ATOM 765  N N   . ARG A 1 100 ? 334.905 355.364 479.484 1.00 161.25 ? 100 ARG H N   1 
ATOM 766  C CA  . ARG A 1 100 ? 334.328 355.377 478.149 1.00 161.25 ? 100 ARG H CA  1 
ATOM 767  C C   . ARG A 1 100 ? 335.400 355.702 477.120 1.00 161.25 ? 100 ARG H C   1 
ATOM 768  O O   . ARG A 1 100 ? 336.310 356.493 477.370 1.00 161.25 ? 100 ARG H O   1 
ATOM 769  C CB  . ARG A 1 100 ? 333.192 356.401 478.048 1.00 161.25 ? 100 ARG H CB  1 
ATOM 770  C CG  . ARG A 1 100 ? 332.217 356.122 476.923 1.00 161.25 ? 100 ARG H CG  1 
ATOM 771  C CD  . ARG A 1 100 ? 331.390 357.337 476.568 1.00 161.25 ? 100 ARG H CD  1 
ATOM 772  N NE  . ARG A 1 100 ? 332.211 358.470 476.163 1.00 161.25 ? 100 ARG H NE  1 
ATOM 773  C CZ  . ARG A 1 100 ? 331.770 359.469 475.408 1.00 161.25 ? 100 ARG H CZ  1 
ATOM 774  N NH1 . ARG A 1 100 ? 330.518 359.465 474.975 1.00 161.25 ? 100 ARG H NH1 1 
ATOM 775  N NH2 . ARG A 1 100 ? 332.577 360.467 475.082 1.00 161.25 ? 100 ARG H NH2 1 
ATOM 776  N N   . SER A 1 101 ? 335.279 355.088 475.948 1.00 155.14 ? 101 SER H N   1 
ATOM 777  C CA  . SER A 1 101 ? 336.173 355.368 474.838 1.00 155.14 ? 101 SER H CA  1 
ATOM 778  C C   . SER A 1 101 ? 335.349 355.719 473.610 1.00 155.14 ? 101 SER H C   1 
ATOM 779  O O   . SER A 1 101 ? 334.271 355.168 473.380 1.00 155.14 ? 101 SER H O   1 
ATOM 780  C CB  . SER A 1 101 ? 337.089 354.178 474.541 1.00 155.14 ? 101 SER H CB  1 
ATOM 781  O OG  . SER A 1 101 ? 337.620 354.275 473.235 1.00 155.14 ? 101 SER H OG  1 
ATOM 782  N N   . ARG A 1 102 ? 335.876 356.631 472.802 0.00 148.11 ? 102 ARG H N   1 
ATOM 783  C CA  . ARG A 1 102 ? 335.128 357.148 471.668 0.00 148.11 ? 102 ARG H CA  1 
ATOM 784  C C   . ARG A 1 102 ? 336.080 357.388 470.511 0.00 148.11 ? 102 ARG H C   1 
ATOM 785  O O   . ARG A 1 102 ? 337.301 357.396 470.679 0.00 148.11 ? 102 ARG H O   1 
ATOM 786  C CB  . ARG A 1 102 ? 334.401 358.445 472.026 0.00 148.11 ? 102 ARG H CB  1 
ATOM 787  C CG  . ARG A 1 102 ? 335.298 359.460 472.703 0.00 148.11 ? 102 ARG H CG  1 
ATOM 788  C CD  . ARG A 1 102 ? 334.803 360.875 472.486 0.00 148.11 ? 102 ARG H CD  1 
ATOM 789  N NE  . ARG A 1 102 ? 335.150 361.376 471.160 0.00 148.11 ? 102 ARG H NE  1 
ATOM 790  C CZ  . ARG A 1 102 ? 334.939 362.624 470.757 0.00 148.11 ? 102 ARG H CZ  1 
ATOM 791  N NH1 . ARG A 1 102 ? 334.381 363.502 471.578 0.00 148.11 ? 102 ARG H NH1 1 
ATOM 792  N NH2 . ARG A 1 102 ? 335.284 362.994 469.533 0.00 148.11 ? 102 ARG H NH2 1 
ATOM 793  N N   . TYR A 1 103 ? 335.505 357.591 469.330 1.00 137.05 ? 103 TYR H N   1 
ATOM 794  C CA  . TYR A 1 103 ? 336.282 357.887 468.135 1.00 137.05 ? 103 TYR H CA  1 
ATOM 795  C C   . TYR A 1 103 ? 336.643 359.365 468.133 1.00 137.05 ? 103 TYR H C   1 
ATOM 796  O O   . TYR A 1 103 ? 335.844 360.204 468.559 1.00 137.05 ? 103 TYR H O   1 
ATOM 797  C CB  . TYR A 1 103 ? 335.501 357.533 466.874 1.00 137.05 ? 103 TYR H CB  1 
ATOM 798  C CG  . TYR A 1 103 ? 334.977 356.122 466.833 1.00 137.05 ? 103 TYR H CG  1 
ATOM 799  C CD1 . TYR A 1 103 ? 335.835 355.051 466.639 1.00 137.05 ? 103 TYR H CD1 1 
ATOM 800  C CD2 . TYR A 1 103 ? 333.623 355.862 466.984 1.00 137.05 ? 103 TYR H CD2 1 
ATOM 801  C CE1 . TYR A 1 103 ? 335.360 353.760 466.592 1.00 137.05 ? 103 TYR H CE1 1 
ATOM 802  C CE2 . TYR A 1 103 ? 333.139 354.575 466.938 1.00 137.05 ? 103 TYR H CE2 1 
ATOM 803  C CZ  . TYR A 1 103 ? 334.012 353.529 466.743 1.00 137.05 ? 103 TYR H CZ  1 
ATOM 804  O OH  . TYR A 1 103 ? 333.535 352.243 466.699 1.00 137.05 ? 103 TYR H OH  1 
ATOM 805  N N   . TYR A 1 104 ? 337.847 359.682 467.664 1.00 148.61 ? 104 TYR H N   1 
ATOM 806  C CA  . TYR A 1 104 ? 338.285 361.071 467.610 1.00 148.61 ? 104 TYR H CA  1 
ATOM 807  C C   . TYR A 1 104 ? 338.163 361.649 466.205 1.00 148.61 ? 104 TYR H C   1 
ATOM 808  O O   . TYR A 1 104 ? 337.481 362.656 465.998 1.00 148.61 ? 104 TYR H O   1 
ATOM 809  C CB  . TYR A 1 104 ? 339.717 361.176 468.130 1.00 148.61 ? 104 TYR H CB  1 
ATOM 810  C CG  . TYR A 1 104 ? 339.781 360.901 469.602 1.00 148.61 ? 104 TYR H CG  1 
ATOM 811  C CD1 . TYR A 1 104 ? 339.468 361.893 470.522 1.00 148.61 ? 104 TYR H CD1 1 
ATOM 812  C CD2 . TYR A 1 104 ? 340.112 359.641 470.074 1.00 148.61 ? 104 TYR H CD2 1 
ATOM 813  C CE1 . TYR A 1 104 ? 339.509 361.644 471.871 1.00 148.61 ? 104 TYR H CE1 1 
ATOM 814  C CE2 . TYR A 1 104 ? 340.156 359.379 471.422 1.00 148.61 ? 104 TYR H CE2 1 
ATOM 815  C CZ  . TYR A 1 104 ? 339.853 360.385 472.315 1.00 148.61 ? 104 TYR H CZ  1 
ATOM 816  O OH  . TYR A 1 104 ? 339.890 360.130 473.660 1.00 148.61 ? 104 TYR H OH  1 
ATOM 817  N N   . GLY A 1 105 ? 338.817 361.027 465.234 1.00 135.31 ? 105 GLY H N   1 
ATOM 818  C CA  . GLY A 1 105 ? 338.604 361.402 463.854 1.00 135.31 ? 105 GLY H CA  1 
ATOM 819  C C   . GLY A 1 105 ? 337.527 360.513 463.285 1.00 135.31 ? 105 GLY H C   1 
ATOM 820  O O   . GLY A 1 105 ? 336.363 360.599 463.683 1.00 135.31 ? 105 GLY H O   1 
ATOM 821  N N   . GLY A 1 106 ? 337.903 359.655 462.351 1.00 126.09 ? 106 GLY H N   1 
ATOM 822  C CA  . GLY A 1 106 ? 337.063 358.553 461.952 1.00 126.09 ? 106 GLY H CA  1 
ATOM 823  C C   . GLY A 1 106 ? 337.570 357.217 462.425 1.00 126.09 ? 106 GLY H C   1 
ATOM 824  O O   . GLY A 1 106 ? 336.855 356.218 462.309 1.00 126.09 ? 106 GLY H O   1 
ATOM 825  N N   . THR A 1 107 ? 338.786 357.170 462.956 1.00 134.06 ? 107 THR H N   1 
ATOM 826  C CA  . THR A 1 107 ? 339.390 355.937 463.420 1.00 134.06 ? 107 THR H CA  1 
ATOM 827  C C   . THR A 1 107 ? 339.175 355.760 464.916 1.00 134.06 ? 107 THR H C   1 
ATOM 828  O O   . THR A 1 107 ? 338.520 356.565 465.582 1.00 134.06 ? 107 THR H O   1 
ATOM 829  C CB  . THR A 1 107 ? 340.880 355.921 463.106 1.00 134.06 ? 107 THR H CB  1 
ATOM 830  O OG1 . THR A 1 107 ? 341.439 354.670 463.521 1.00 134.06 ? 107 THR H OG1 1 
ATOM 831  C CG2 . THR A 1 107 ? 341.578 357.049 463.832 1.00 134.06 ? 107 THR H CG2 1 
ATOM 832  N N   . TYR A 1 108 ? 339.747 354.685 465.445 0.00 143.52 ? 108 TYR H N   1 
ATOM 833  C CA  . TYR A 1 108 ? 339.644 354.343 466.859 0.00 143.52 ? 108 TYR H CA  1 
ATOM 834  C C   . TYR A 1 108 ? 341.012 354.523 467.504 0.00 143.52 ? 108 TYR H C   1 
ATOM 835  O O   . TYR A 1 108 ? 341.914 353.707 467.317 0.00 143.52 ? 108 TYR H O   1 
ATOM 836  C CB  . TYR A 1 108 ? 339.143 352.922 467.052 0.00 143.52 ? 108 TYR H CB  1 
ATOM 837  C CG  . TYR A 1 108 ? 338.906 352.584 468.500 0.00 143.52 ? 108 TYR H CG  1 
ATOM 838  C CD1 . TYR A 1 108 ? 337.757 353.008 469.141 0.00 143.52 ? 108 TYR H CD1 1 
ATOM 839  C CD2 . TYR A 1 108 ? 339.834 351.855 469.230 0.00 143.52 ? 108 TYR H CD2 1 
ATOM 840  C CE1 . TYR A 1 108 ? 337.529 352.710 470.463 0.00 143.52 ? 108 TYR H CE1 1 
ATOM 841  C CE2 . TYR A 1 108 ? 339.615 351.557 470.559 0.00 143.52 ? 108 TYR H CE2 1 
ATOM 842  C CZ  . TYR A 1 108 ? 338.459 351.989 471.169 0.00 143.52 ? 108 TYR H CZ  1 
ATOM 843  O OH  . TYR A 1 108 ? 338.223 351.699 472.490 0.00 143.52 ? 108 TYR H OH  1 
ATOM 844  N N   . ARG A 1 109 ? 341.160 355.593 468.272 0.00 145.80 ? 109 ARG H N   1 
ATOM 845  C CA  . ARG A 1 109 ? 342.298 355.684 469.165 0.00 145.80 ? 109 ARG H CA  1 
ATOM 846  C C   . ARG A 1 109 ? 341.979 354.940 470.456 0.00 145.80 ? 109 ARG H C   1 
ATOM 847  O O   . ARG A 1 109 ? 340.846 354.519 470.694 0.00 145.80 ? 109 ARG H O   1 
ATOM 848  C CB  . ARG A 1 109 ? 342.653 357.142 469.450 0.00 145.80 ? 109 ARG H CB  1 
ATOM 849  C CG  . ARG A 1 109 ? 343.380 357.836 468.308 0.00 145.80 ? 109 ARG H CG  1 
ATOM 850  C CD  . ARG A 1 109 ? 342.408 358.544 467.380 0.00 145.80 ? 109 ARG H CD  1 
ATOM 851  N NE  . ARG A 1 109 ? 343.047 359.028 466.163 0.00 145.80 ? 109 ARG H NE  1 
ATOM 852  C CZ  . ARG A 1 109 ? 343.527 360.254 466.005 0.00 145.80 ? 109 ARG H CZ  1 
ATOM 853  N NH1 . ARG A 1 109 ? 344.086 360.601 464.857 0.00 145.80 ? 109 ARG H NH1 1 
ATOM 854  N NH2 . ARG A 1 109 ? 343.450 361.130 466.995 0.00 145.80 ? 109 ARG H NH2 1 
ATOM 855  N N   . TYR A 1 110 ? 342.991 354.777 471.299 0.00 150.31 ? 110 TYR H N   1 
ATOM 856  C CA  . TYR A 1 110 ? 342.870 353.933 472.485 0.00 150.31 ? 110 TYR H CA  1 
ATOM 857  C C   . TYR A 1 110 ? 342.883 354.735 473.773 0.00 150.31 ? 110 TYR H C   1 
ATOM 858  O O   . TYR A 1 110 ? 343.506 354.334 474.756 0.00 150.31 ? 110 TYR H O   1 
ATOM 859  C CB  . TYR A 1 110 ? 343.974 352.887 472.494 0.00 150.31 ? 110 TYR H CB  1 
ATOM 860  C CG  . TYR A 1 110 ? 343.661 351.696 471.632 0.00 150.31 ? 110 TYR H CG  1 
ATOM 861  C CD1 . TYR A 1 110 ? 343.721 351.783 470.251 0.00 150.31 ? 110 TYR H CD1 1 
ATOM 862  C CD2 . TYR A 1 110 ? 343.304 350.483 472.200 0.00 150.31 ? 110 TYR H CD2 1 
ATOM 863  C CE1 . TYR A 1 110 ? 343.431 350.698 469.461 0.00 150.31 ? 110 TYR H CE1 1 
ATOM 864  C CE2 . TYR A 1 110 ? 343.015 349.390 471.415 0.00 150.31 ? 110 TYR H CE2 1 
ATOM 865  C CZ  . TYR A 1 110 ? 343.078 349.507 470.049 0.00 150.31 ? 110 TYR H CZ  1 
ATOM 866  O OH  . TYR A 1 110 ? 342.796 348.425 469.260 0.00 150.31 ? 110 TYR H OH  1 
ATOM 867  N N   . ALA A 1 111 ? 342.210 355.877 473.795 0.67 156.37 ? 111 ALA H N   1 
ATOM 868  C CA  . ALA A 1 111 ? 342.144 356.675 475.005 0.67 156.37 ? 111 ALA H CA  1 
ATOM 869  C C   . ALA A 1 111 ? 340.814 356.460 475.725 0.67 156.37 ? 111 ALA H C   1 
ATOM 870  O O   . ALA A 1 111 ? 339.832 355.990 475.147 0.67 156.37 ? 111 ALA H O   1 
ATOM 871  C CB  . ALA A 1 111 ? 342.335 358.152 474.677 0.67 156.37 ? 111 ALA H CB  1 
ATOM 872  N N   . LEU A 1 112 ? 340.795 356.813 477.009 1.00 165.98 ? 112 LEU H N   1 
ATOM 873  C CA  . LEU A 1 112 ? 339.617 356.662 477.863 1.00 165.98 ? 112 LEU H CA  1 
ATOM 874  C C   . LEU A 1 112 ? 339.313 358.030 478.464 1.00 165.98 ? 112 LEU H C   1 
ATOM 875  O O   . LEU A 1 112 ? 339.946 358.430 479.445 1.00 165.98 ? 112 LEU H O   1 
ATOM 876  C CB  . LEU A 1 112 ? 339.861 355.629 478.955 1.00 165.98 ? 112 LEU H CB  1 
ATOM 877  C CG  . LEU A 1 112 ? 340.719 354.408 478.622 1.00 165.98 ? 112 LEU H CG  1 
ATOM 878  C CD1 . LEU A 1 112 ? 340.989 353.597 479.873 1.00 165.98 ? 112 LEU H CD1 1 
ATOM 879  C CD2 . LEU A 1 112 ? 340.036 353.544 477.583 1.00 165.98 ? 112 LEU H CD2 1 
ATOM 880  N N   . ASP A 1 113 ? 338.335 358.739 477.900 1.00 172.19 ? 113 ASP H N   1 
ATOM 881  C CA  . ASP A 1 113 ? 338.188 360.164 478.186 1.00 172.19 ? 113 ASP H CA  1 
ATOM 882  C C   . ASP A 1 113 ? 337.345 360.453 479.430 1.00 172.19 ? 113 ASP H C   1 
ATOM 883  O O   . ASP A 1 113 ? 337.699 361.323 480.231 1.00 172.19 ? 113 ASP H O   1 
ATOM 884  C CB  . ASP A 1 113 ? 337.642 360.891 476.946 1.00 172.19 ? 113 ASP H CB  1 
ATOM 885  C CG  . ASP A 1 113 ? 336.215 360.511 476.601 1.00 172.19 ? 113 ASP H CG  1 
ATOM 886  O OD1 . ASP A 1 113 ? 335.752 359.430 477.024 1.00 172.19 ? 113 ASP H OD1 1 
ATOM 887  O OD2 . ASP A 1 113 ? 335.561 361.295 475.885 1.00 172.19 ? 113 ASP H OD2 1 
ATOM 888  N N   . TYR A 1 114 ? 336.239 359.741 479.610 1.00 175.39 ? 114 TYR H N   1 
ATOM 889  C CA  . TYR A 1 114 ? 335.278 360.064 480.655 1.00 175.39 ? 114 TYR H CA  1 
ATOM 890  C C   . TYR A 1 114 ? 335.186 358.920 481.651 1.00 175.39 ? 114 TYR H C   1 
ATOM 891  O O   . TYR A 1 114 ? 334.918 357.777 481.270 1.00 175.39 ? 114 TYR H O   1 
ATOM 892  C CB  . TYR A 1 114 ? 333.919 360.377 480.043 1.00 175.39 ? 114 TYR H CB  1 
ATOM 893  C CG  . TYR A 1 114 ? 333.933 361.670 479.266 1.00 175.39 ? 114 TYR H CG  1 
ATOM 894  C CD1 . TYR A 1 114 ? 334.639 362.770 479.739 1.00 175.39 ? 114 TYR H CD1 1 
ATOM 895  C CD2 . TYR A 1 114 ? 333.248 361.795 478.064 1.00 175.39 ? 114 TYR H CD2 1 
ATOM 896  C CE1 . TYR A 1 114 ? 334.662 363.960 479.041 1.00 175.39 ? 114 TYR H CE1 1 
ATOM 897  C CE2 . TYR A 1 114 ? 333.263 362.986 477.356 1.00 175.39 ? 114 TYR H CE2 1 
ATOM 898  C CZ  . TYR A 1 114 ? 333.975 364.062 477.851 1.00 175.39 ? 114 TYR H CZ  1 
ATOM 899  O OH  . TYR A 1 114 ? 333.998 365.248 477.156 1.00 175.39 ? 114 TYR H OH  1 
ATOM 900  N N   . TRP A 1 115 ? 335.393 359.236 482.923 1.00 178.14 ? 115 TRP H N   1 
ATOM 901  C CA  . TRP A 1 115 ? 335.587 358.237 483.957 1.00 178.14 ? 115 TRP H CA  1 
ATOM 902  C C   . TRP A 1 115 ? 334.504 358.345 485.018 1.00 178.14 ? 115 TRP H C   1 
ATOM 903  O O   . TRP A 1 115 ? 333.896 359.401 485.208 1.00 178.14 ? 115 TRP H O   1 
ATOM 904  C CB  . TRP A 1 115 ? 336.965 358.390 484.604 1.00 178.14 ? 115 TRP H CB  1 
ATOM 905  C CG  . TRP A 1 115 ? 338.092 357.988 483.705 1.00 178.14 ? 115 TRP H CG  1 
ATOM 906  C CD1 . TRP A 1 115 ? 338.461 358.582 482.534 1.00 178.14 ? 115 TRP H CD1 1 
ATOM 907  C CD2 . TRP A 1 115 ? 338.999 356.903 483.905 1.00 178.14 ? 115 TRP H CD2 1 
ATOM 908  N NE1 . TRP A 1 115 ? 339.538 357.932 481.992 1.00 178.14 ? 115 TRP H NE1 1 
ATOM 909  C CE2 . TRP A 1 115 ? 339.889 356.897 482.816 1.00 178.14 ? 115 TRP H CE2 1 
ATOM 910  C CE3 . TRP A 1 115 ? 339.146 355.936 484.898 1.00 178.14 ? 115 TRP H CE3 1 
ATOM 911  C CZ2 . TRP A 1 115 ? 340.907 355.963 482.694 1.00 178.14 ? 115 TRP H CZ2 1 
ATOM 912  C CZ3 . TRP A 1 115 ? 340.155 355.011 484.775 1.00 178.14 ? 115 TRP H CZ3 1 
ATOM 913  C CH2 . TRP A 1 115 ? 341.023 355.030 483.682 1.00 178.14 ? 115 TRP H CH2 1 
ATOM 914  N N   . GLY A 1 116 ? 334.269 357.237 485.705 1.00 185.08 ? 116 GLY H N   1 
ATOM 915  C CA  . GLY A 1 116 ? 333.324 357.223 486.797 1.00 185.08 ? 116 GLY H CA  1 
ATOM 916  C C   . GLY A 1 116 ? 333.938 357.703 488.098 1.00 185.08 ? 116 GLY H C   1 
ATOM 917  O O   . GLY A 1 116 ? 335.075 358.168 488.154 1.00 185.08 ? 116 GLY H O   1 
ATOM 918  N N   . GLN A 1 117 ? 333.155 357.576 489.170 1.00 191.77 ? 117 GLN H N   1 
ATOM 919  C CA  . GLN A 1 117 ? 333.587 358.055 490.476 1.00 191.77 ? 117 GLN H CA  1 
ATOM 920  C C   . GLN A 1 117 ? 334.467 357.054 491.208 1.00 191.77 ? 117 GLN H C   1 
ATOM 921  O O   . GLN A 1 117 ? 335.244 357.455 492.079 1.00 191.77 ? 117 GLN H O   1 
ATOM 922  C CB  . GLN A 1 117 ? 332.375 358.400 491.345 1.00 191.77 ? 117 GLN H CB  1 
ATOM 923  C CG  . GLN A 1 117 ? 331.336 359.279 490.661 1.00 191.77 ? 117 GLN H CG  1 
ATOM 924  C CD  . GLN A 1 117 ? 330.233 358.472 490.005 1.00 191.77 ? 117 GLN H CD  1 
ATOM 925  O OE1 . GLN A 1 117 ? 329.712 357.524 490.589 1.00 191.77 ? 117 GLN H OE1 1 
ATOM 926  N NE2 . GLN A 1 117 ? 329.884 358.836 488.778 1.00 191.77 ? 117 GLN H NE2 1 
ATOM 927  N N   . GLY A 1 118 ? 334.359 355.771 490.886 1.00 191.83 ? 118 GLY H N   1 
ATOM 928  C CA  . GLY A 1 118 ? 335.231 354.778 491.474 1.00 191.83 ? 118 GLY H CA  1 
ATOM 929  C C   . GLY A 1 118 ? 334.687 354.166 492.745 1.00 191.83 ? 118 GLY H C   1 
ATOM 930  O O   . GLY A 1 118 ? 334.505 354.862 493.748 1.00 191.83 ? 118 GLY H O   1 
ATOM 931  N N   . THR A 1 119 ? 334.430 352.863 492.715 1.00 192.33 ? 119 THR H N   1 
ATOM 932  C CA  . THR A 1 119 ? 334.047 352.108 493.895 1.00 192.33 ? 119 THR H CA  1 
ATOM 933  C C   . THR A 1 119 ? 335.231 351.276 494.375 1.00 192.33 ? 119 THR H C   1 
ATOM 934  O O   . THR A 1 119 ? 336.065 350.828 493.586 1.00 192.33 ? 119 THR H O   1 
ATOM 935  C CB  . THR A 1 119 ? 332.834 351.216 493.609 1.00 192.33 ? 119 THR H CB  1 
ATOM 936  O OG1 . THR A 1 119 ? 332.602 350.346 494.722 1.00 192.33 ? 119 THR H OG1 1 
ATOM 937  C CG2 . THR A 1 119 ? 333.044 350.399 492.347 1.00 192.33 ? 119 THR H CG2 1 
ATOM 938  N N   . SER A 1 120 ? 335.304 351.086 495.689 1.00 190.02 ? 120 SER H N   1 
ATOM 939  C CA  . SER A 1 120 ? 336.458 350.470 496.329 1.00 190.02 ? 120 SER H CA  1 
ATOM 940  C C   . SER A 1 120 ? 336.146 349.033 496.713 1.00 190.02 ? 120 SER H C   1 
ATOM 941  O O   . SER A 1 120 ? 335.168 348.768 497.418 1.00 190.02 ? 120 SER H O   1 
ATOM 942  C CB  . SER A 1 120 ? 336.875 351.251 497.573 1.00 190.02 ? 120 SER H CB  1 
ATOM 943  O OG  . SER A 1 120 ? 335.848 351.225 498.548 1.00 190.02 ? 120 SER H OG  1 
ATOM 944  N N   . VAL A 1 121 ? 336.992 348.109 496.262 1.00 192.45 ? 121 VAL H N   1 
ATOM 945  C CA  . VAL A 1 121 ? 336.832 346.689 496.555 1.00 192.45 ? 121 VAL H CA  1 
ATOM 946  C C   . VAL A 1 121 ? 338.032 346.235 497.372 1.00 192.45 ? 121 VAL H C   1 
ATOM 947  O O   . VAL A 1 121 ? 339.167 346.266 496.885 1.00 192.45 ? 121 VAL H O   1 
ATOM 948  C CB  . VAL A 1 121 ? 336.700 345.838 495.281 1.00 192.45 ? 121 VAL H CB  1 
ATOM 949  C CG1 . VAL A 1 121 ? 336.691 344.367 495.633 1.00 192.45 ? 121 VAL H CG1 1 
ATOM 950  C CG2 . VAL A 1 121 ? 335.436 346.204 494.533 1.00 192.45 ? 121 VAL H CG2 1 
ATOM 951  N N   . THR A 1 122 ? 337.787 345.809 498.604 1.00 199.97 ? 122 THR H N   1 
ATOM 952  C CA  . THR A 1 122 ? 338.832 345.310 499.480 1.00 199.97 ? 122 THR H CA  1 
ATOM 953  C C   . THR A 1 122 ? 338.556 343.860 499.845 1.00 199.97 ? 122 THR H C   1 
ATOM 954  O O   . THR A 1 122 ? 337.435 343.366 499.701 1.00 199.97 ? 122 THR H O   1 
ATOM 955  C CB  . THR A 1 122 ? 338.946 346.144 500.758 1.00 199.97 ? 122 THR H CB  1 
ATOM 956  O OG1 . THR A 1 122 ? 339.990 345.612 501.583 1.00 199.97 ? 122 THR H OG1 1 
ATOM 957  C CG2 . THR A 1 122 ? 337.641 346.126 501.525 1.00 199.97 ? 122 THR H CG2 1 
ATOM 958  N N   . VAL A 1 123 ? 339.601 343.180 500.310 1.00 200.24 ? 123 VAL H N   1 
ATOM 959  C CA  . VAL A 1 123 ? 339.525 341.784 500.712 1.00 200.24 ? 123 VAL H CA  1 
ATOM 960  C C   . VAL A 1 123 ? 340.081 341.653 502.122 1.00 200.24 ? 123 VAL H C   1 
ATOM 961  O O   . VAL A 1 123 ? 340.636 342.597 502.688 1.00 200.24 ? 123 VAL H O   1 
ATOM 962  C CB  . VAL A 1 123 ? 340.292 340.861 499.748 1.00 200.24 ? 123 VAL H CB  1 
ATOM 963  C CG1 . VAL A 1 123 ? 339.644 340.859 498.377 1.00 200.24 ? 123 VAL H CG1 1 
ATOM 964  C CG2 . VAL A 1 123 ? 341.722 341.327 499.644 1.00 200.24 ? 123 VAL H CG2 1 
ATOM 965  N N   . SER A 1 124 ? 339.929 340.461 502.684 1.00 200.91 ? 124 SER H N   1 
ATOM 966  C CA  . SER A 1 124 ? 340.417 340.183 504.028 1.00 200.91 ? 124 SER H CA  1 
ATOM 967  C C   . SER A 1 124 ? 341.088 338.815 504.102 1.00 200.91 ? 124 SER H C   1 
ATOM 968  O O   . SER A 1 124 ? 340.633 337.925 504.819 1.00 200.91 ? 124 SER H O   1 
ATOM 969  C CB  . SER A 1 124 ? 339.271 340.268 505.037 1.00 200.91 ? 124 SER H CB  1 
ATOM 970  O OG  . SER A 1 124 ? 338.293 339.275 504.786 1.00 200.91 ? 124 SER H OG  1 
ATOM 971  N N   . ASN B 2 2   ? 355.461 345.698 476.745 1.00 174.98 ? 2   ASN L N   1 
ATOM 972  C CA  . ASN B 2 2   ? 356.067 347.024 476.741 1.00 174.98 ? 2   ASN L CA  1 
ATOM 973  C C   . ASN B 2 2   ? 355.900 347.706 478.092 1.00 174.98 ? 2   ASN L C   1 
ATOM 974  O O   . ASN B 2 2   ? 354.831 347.654 478.686 1.00 174.98 ? 2   ASN L O   1 
ATOM 975  C CB  . ASN B 2 2   ? 355.452 347.888 475.640 1.00 174.98 ? 2   ASN L CB  1 
ATOM 976  C CG  . ASN B 2 2   ? 356.183 349.202 475.450 1.00 174.98 ? 2   ASN L CG  1 
ATOM 977  O OD1 . ASN B 2 2   ? 357.298 349.385 475.936 1.00 174.98 ? 2   ASN L OD1 1 
ATOM 978  N ND2 . ASN B 2 2   ? 355.556 350.126 474.733 1.00 174.98 ? 2   ASN L ND2 1 
ATOM 979  N N   . VAL B 2 3   ? 356.961 348.350 478.573 1.00 175.53 ? 3   VAL L N   1 
ATOM 980  C CA  . VAL B 2 3   ? 356.913 349.096 479.822 1.00 175.53 ? 3   VAL L CA  1 
ATOM 981  C C   . VAL B 2 3   ? 357.263 350.547 479.534 1.00 175.53 ? 3   VAL L C   1 
ATOM 982  O O   . VAL B 2 3   ? 357.867 350.872 478.506 1.00 175.53 ? 3   VAL L O   1 
ATOM 983  C CB  . VAL B 2 3   ? 357.854 348.519 480.902 1.00 175.53 ? 3   VAL L CB  1 
ATOM 984  C CG1 . VAL B 2 3   ? 357.493 347.074 481.211 1.00 175.53 ? 3   VAL L CG1 1 
ATOM 985  C CG2 . VAL B 2 3   ? 359.305 348.643 480.481 1.00 175.53 ? 3   VAL L CG2 1 
ATOM 986  N N   . LEU B 2 4   ? 356.873 351.422 480.451 1.00 172.77 ? 4   LEU L N   1 
ATOM 987  C CA  . LEU B 2 4   ? 357.016 352.859 480.284 1.00 172.77 ? 4   LEU L CA  1 
ATOM 988  C C   . LEU B 2 4   ? 357.872 353.420 481.404 1.00 172.77 ? 4   LEU L C   1 
ATOM 989  O O   . LEU B 2 4   ? 357.476 353.381 482.573 1.00 172.77 ? 4   LEU L O   1 
ATOM 990  C CB  . LEU B 2 4   ? 355.648 353.533 480.281 1.00 172.77 ? 4   LEU L CB  1 
ATOM 991  C CG  . LEU B 2 4   ? 354.712 352.977 479.216 1.00 172.77 ? 4   LEU L CG  1 
ATOM 992  C CD1 . LEU B 2 4   ? 353.353 353.613 479.327 1.00 172.77 ? 4   LEU L CD1 1 
ATOM 993  C CD2 . LEU B 2 4   ? 355.313 353.217 477.847 1.00 172.77 ? 4   LEU L CD2 1 
ATOM 994  N N   . THR B 2 5   ? 359.033 353.955 481.046 1.00 178.65 ? 5   THR L N   1 
ATOM 995  C CA  . THR B 2 5   ? 359.949 354.533 482.017 1.00 178.65 ? 5   THR L CA  1 
ATOM 996  C C   . THR B 2 5   ? 359.740 356.037 482.032 1.00 178.65 ? 5   THR L C   1 
ATOM 997  O O   . THR B 2 5   ? 360.377 356.763 481.261 1.00 178.65 ? 5   THR L O   1 
ATOM 998  C CB  . THR B 2 5   ? 361.407 354.198 481.689 1.00 178.65 ? 5   THR L CB  1 
ATOM 999  O OG1 . THR B 2 5   ? 361.776 354.808 480.450 1.00 178.65 ? 5   THR L OG1 1 
ATOM 1000 C CG2 . THR B 2 5   ? 361.592 352.696 481.569 1.00 178.65 ? 5   THR L CG2 1 
ATOM 1001 N N   . GLN B 2 6   ? 358.845 356.499 482.895 1.00 185.79 ? 6   GLN L N   1 
ATOM 1002 C CA  . GLN B 2 6   ? 358.711 357.925 483.129 1.00 185.79 ? 6   GLN L CA  1 
ATOM 1003 C C   . GLN B 2 6   ? 359.875 358.403 483.981 1.00 185.79 ? 6   GLN L C   1 
ATOM 1004 O O   . GLN B 2 6   ? 360.430 357.655 484.790 1.00 185.79 ? 6   GLN L O   1 
ATOM 1005 C CB  . GLN B 2 6   ? 357.388 358.249 483.819 1.00 185.79 ? 6   GLN L CB  1 
ATOM 1006 C CG  . GLN B 2 6   ? 356.159 357.745 483.092 1.00 185.79 ? 6   GLN L CG  1 
ATOM 1007 C CD  . GLN B 2 6   ? 354.887 358.393 483.600 1.00 185.79 ? 6   GLN L CD  1 
ATOM 1008 O OE1 . GLN B 2 6   ? 353.784 357.943 483.299 1.00 185.79 ? 6   GLN L OE1 1 
ATOM 1009 N NE2 . GLN B 2 6   ? 355.036 359.459 484.377 1.00 185.79 ? 6   GLN L NE2 1 
ATOM 1010 N N   . SER B 2 7   ? 360.246 359.669 483.791 1.00 198.05 ? 7   SER L N   1 
ATOM 1011 C CA  . SER B 2 7   ? 361.430 360.190 484.442 1.00 198.05 ? 7   SER L CA  1 
ATOM 1012 C C   . SER B 2 7   ? 361.374 361.705 484.515 1.00 198.05 ? 7   SER L C   1 
ATOM 1013 O O   . SER B 2 7   ? 361.172 362.357 483.482 1.00 198.05 ? 7   SER L O   1 
ATOM 1014 C CB  . SER B 2 7   ? 362.702 359.771 483.700 1.00 198.05 ? 7   SER L CB  1 
ATOM 1015 O OG  . SER B 2 7   ? 363.008 360.690 482.666 1.00 198.05 ? 7   SER L OG  1 
ATOM 1016 N N   . PRO B 2 8   ? 361.552 362.294 485.704 1.00 202.51 ? 8   PRO L N   1 
ATOM 1017 C CA  . PRO B 2 8   ? 361.637 361.626 487.005 1.00 202.51 ? 8   PRO L CA  1 
ATOM 1018 C C   . PRO B 2 8   ? 360.290 361.620 487.725 1.00 202.51 ? 8   PRO L C   1 
ATOM 1019 O O   . PRO B 2 8   ? 359.407 362.387 487.343 1.00 202.51 ? 8   PRO L O   1 
ATOM 1020 C CB  . PRO B 2 8   ? 362.664 362.473 487.754 1.00 202.51 ? 8   PRO L CB  1 
ATOM 1021 C CG  . PRO B 2 8   ? 362.465 363.838 487.210 1.00 202.51 ? 8   PRO L CG  1 
ATOM 1022 C CD  . PRO B 2 8   ? 362.019 363.688 485.778 1.00 202.51 ? 8   PRO L CD  1 
ATOM 1023 N N   . PRO B 2 9   ? 360.119 360.754 488.729 1.00 200.43 ? 9   PRO L N   1 
ATOM 1024 C CA  . PRO B 2 9   ? 358.830 360.738 489.439 1.00 200.43 ? 9   PRO L CA  1 
ATOM 1025 C C   . PRO B 2 9   ? 358.598 361.947 490.327 1.00 200.43 ? 9   PRO L C   1 
ATOM 1026 O O   . PRO B 2 9   ? 357.457 362.412 490.431 1.00 200.43 ? 9   PRO L O   1 
ATOM 1027 C CB  . PRO B 2 9   ? 358.900 359.439 490.253 1.00 200.43 ? 9   PRO L CB  1 
ATOM 1028 C CG  . PRO B 2 9   ? 359.873 358.587 489.517 1.00 200.43 ? 9   PRO L CG  1 
ATOM 1029 C CD  . PRO B 2 9   ? 360.906 359.541 489.012 1.00 200.43 ? 9   PRO L CD  1 
ATOM 1030 N N   . ILE B 2 10  ? 359.636 362.485 490.959 1.00 202.64 ? 10  ILE L N   1 
ATOM 1031 C CA  . ILE B 2 10  ? 359.487 363.569 491.923 1.00 202.64 ? 10  ILE L CA  1 
ATOM 1032 C C   . ILE B 2 10  ? 360.023 364.854 491.310 1.00 202.64 ? 10  ILE L C   1 
ATOM 1033 O O   . ILE B 2 10  ? 361.198 364.926 490.932 1.00 202.64 ? 10  ILE L O   1 
ATOM 1034 C CB  . ILE B 2 10  ? 360.207 363.255 493.248 1.00 202.64 ? 10  ILE L CB  1 
ATOM 1035 C CG1 . ILE B 2 10  ? 359.436 362.202 494.042 1.00 202.64 ? 10  ILE L CG1 1 
ATOM 1036 C CG2 . ILE B 2 10  ? 360.358 364.516 494.095 1.00 202.64 ? 10  ILE L CG2 1 
ATOM 1037 C CD1 . ILE B 2 10  ? 358.033 362.625 494.420 1.00 202.64 ? 10  ILE L CD1 1 
ATOM 1038 N N   . MET B 2 11  ? 359.151 365.854 491.188 1.00 203.81 ? 11  MET L N   1 
ATOM 1039 C CA  . MET B 2 11  ? 359.543 367.213 490.834 1.00 203.81 ? 11  MET L CA  1 
ATOM 1040 C C   . MET B 2 11  ? 358.711 368.183 491.657 1.00 203.81 ? 11  MET L C   1 
ATOM 1041 O O   . MET B 2 11  ? 357.563 367.882 491.999 1.00 203.81 ? 11  MET L O   1 
ATOM 1042 C CB  . MET B 2 11  ? 359.342 367.533 489.345 1.00 203.81 ? 11  MET L CB  1 
ATOM 1043 C CG  . MET B 2 11  ? 359.949 366.581 488.342 1.00 203.81 ? 11  MET L CG  1 
ATOM 1044 S SD  . MET B 2 11  ? 359.824 367.279 486.692 1.00 203.81 ? 11  MET L SD  1 
ATOM 1045 C CE  . MET B 2 11  ? 359.094 365.912 485.823 1.00 203.81 ? 11  MET L CE  1 
ATOM 1046 N N   . SER B 2 12  ? 359.295 369.331 491.981 1.00 207.52 ? 12  SER L N   1 
ATOM 1047 C CA  . SER B 2 12  ? 358.557 370.467 492.507 1.00 207.52 ? 12  SER L CA  1 
ATOM 1048 C C   . SER B 2 12  ? 358.912 371.706 491.696 1.00 207.52 ? 12  SER L C   1 
ATOM 1049 O O   . SER B 2 12  ? 359.994 371.790 491.108 1.00 207.52 ? 12  SER L O   1 
ATOM 1050 C CB  . SER B 2 12  ? 358.853 370.688 493.988 1.00 207.52 ? 12  SER L CB  1 
ATOM 1051 O OG  . SER B 2 12  ? 358.084 369.800 494.779 1.00 207.52 ? 12  SER L OG  1 
ATOM 1052 N N   . ALA B 2 13  ? 357.995 372.667 491.659 1.00 206.59 ? 13  ALA L N   1 
ATOM 1053 C CA  . ALA B 2 13  ? 358.165 373.812 490.778 1.00 206.59 ? 13  ALA L CA  1 
ATOM 1054 C C   . ALA B 2 13  ? 357.520 375.049 491.385 1.00 206.59 ? 13  ALA L C   1 
ATOM 1055 O O   . ALA B 2 13  ? 356.479 374.959 492.040 1.00 206.59 ? 13  ALA L O   1 
ATOM 1056 C CB  . ALA B 2 13  ? 357.566 373.530 489.399 1.00 206.59 ? 13  ALA L CB  1 
ATOM 1057 N N   . SER B 2 14  ? 358.149 376.198 491.156 1.00 208.66 ? 14  SER L N   1 
ATOM 1058 C CA  . SER B 2 14  ? 357.611 377.486 491.557 1.00 208.66 ? 14  SER L CA  1 
ATOM 1059 C C   . SER B 2 14  ? 356.697 378.033 490.463 1.00 208.66 ? 14  SER L C   1 
ATOM 1060 O O   . SER B 2 14  ? 356.804 377.631 489.302 1.00 208.66 ? 14  SER L O   1 
ATOM 1061 C CB  . SER B 2 14  ? 358.753 378.459 491.839 1.00 208.66 ? 14  SER L CB  1 
ATOM 1062 O OG  . SER B 2 14  ? 359.502 378.050 492.968 1.00 208.66 ? 14  SER L OG  1 
ATOM 1063 N N   . PRO B 2 15  ? 355.764 378.925 490.812 1.00 206.09 ? 15  PRO L N   1 
ATOM 1064 C CA  . PRO B 2 15  ? 354.890 379.515 489.785 1.00 206.09 ? 15  PRO L CA  1 
ATOM 1065 C C   . PRO B 2 15  ? 355.652 380.417 488.822 1.00 206.09 ? 15  PRO L C   1 
ATOM 1066 O O   . PRO B 2 15  ? 356.328 381.361 489.234 1.00 206.09 ? 15  PRO L O   1 
ATOM 1067 C CB  . PRO B 2 15  ? 353.870 380.312 490.607 1.00 206.09 ? 15  PRO L CB  1 
ATOM 1068 C CG  . PRO B 2 15  ? 353.830 379.617 491.920 1.00 206.09 ? 15  PRO L CG  1 
ATOM 1069 C CD  . PRO B 2 15  ? 355.236 379.163 492.170 1.00 206.09 ? 15  PRO L CD  1 
ATOM 1070 N N   . GLY B 2 16  ? 355.532 380.117 487.528 1.00 204.25 ? 16  GLY L N   1 
ATOM 1071 C CA  . GLY B 2 16  ? 356.067 380.956 486.474 1.00 204.25 ? 16  GLY L CA  1 
ATOM 1072 C C   . GLY B 2 16  ? 357.124 380.317 485.596 1.00 204.25 ? 16  GLY L C   1 
ATOM 1073 O O   . GLY B 2 16  ? 357.679 381.012 484.735 1.00 204.25 ? 16  GLY L O   1 
ATOM 1074 N N   . GLU B 2 17  ? 357.424 379.033 485.766 1.00 204.94 ? 17  GLU L N   1 
ATOM 1075 C CA  . GLU B 2 17  ? 358.562 378.439 485.080 1.00 204.94 ? 17  GLU L CA  1 
ATOM 1076 C C   . GLU B 2 17  ? 358.131 377.473 483.974 1.00 204.94 ? 17  GLU L C   1 
ATOM 1077 O O   . GLU B 2 17  ? 356.948 377.199 483.766 1.00 204.94 ? 17  GLU L O   1 
ATOM 1078 C CB  . GLU B 2 17  ? 359.468 377.727 486.082 1.00 204.94 ? 17  GLU L CB  1 
ATOM 1079 C CG  . GLU B 2 17  ? 358.856 376.500 486.717 1.00 204.94 ? 17  GLU L CG  1 
ATOM 1080 C CD  . GLU B 2 17  ? 359.605 376.068 487.960 1.00 204.94 ? 17  GLU L CD  1 
ATOM 1081 O OE1 . GLU B 2 17  ? 359.600 376.821 488.955 1.00 204.94 ? 17  GLU L OE1 1 
ATOM 1082 O OE2 . GLU B 2 17  ? 360.207 374.977 487.944 1.00 204.94 ? 17  GLU L OE2 1 
ATOM 1083 N N   . LYS B 2 18  ? 359.132 376.950 483.268 1.00 196.44 ? 18  LYS L N   1 
ATOM 1084 C CA  . LYS B 2 18  ? 358.962 376.042 482.140 1.00 196.44 ? 18  LYS L CA  1 
ATOM 1085 C C   . LYS B 2 18  ? 359.342 374.634 482.578 1.00 196.44 ? 18  LYS L C   1 
ATOM 1086 O O   . LYS B 2 18  ? 360.516 374.366 482.848 1.00 196.44 ? 18  LYS L O   1 
ATOM 1087 C CB  . LYS B 2 18  ? 359.848 376.476 480.970 1.00 196.44 ? 18  LYS L CB  1 
ATOM 1088 C CG  . LYS B 2 18  ? 359.245 377.490 480.016 1.00 196.44 ? 18  LYS L CG  1 
ATOM 1089 C CD  . LYS B 2 18  ? 358.093 376.901 479.241 1.00 196.44 ? 18  LYS L CD  1 
ATOM 1090 C CE  . LYS B 2 18  ? 358.239 377.165 477.753 1.00 196.44 ? 18  LYS L CE  1 
ATOM 1091 N NZ  . LYS B 2 18  ? 357.067 376.671 476.976 1.00 196.44 ? 18  LYS L NZ  1 
ATOM 1092 N N   . VAL B 2 19  ? 358.359 373.734 482.628 1.00 192.86 ? 19  VAL L N   1 
ATOM 1093 C CA  . VAL B 2 19  ? 358.560 372.411 483.206 1.00 192.86 ? 19  VAL L CA  1 
ATOM 1094 C C   . VAL B 2 19  ? 358.241 371.338 482.167 1.00 192.86 ? 19  VAL L C   1 
ATOM 1095 O O   . VAL B 2 19  ? 357.274 371.430 481.407 1.00 192.86 ? 19  VAL L O   1 
ATOM 1096 C CB  . VAL B 2 19  ? 357.736 372.228 484.517 1.00 192.86 ? 19  VAL L CB  1 
ATOM 1097 C CG1 . VAL B 2 19  ? 356.234 372.386 484.293 1.00 192.86 ? 19  VAL L CG1 1 
ATOM 1098 C CG2 . VAL B 2 19  ? 358.055 370.902 485.202 1.00 192.86 ? 19  VAL L CG2 1 
ATOM 1099 N N   . THR B 2 20  ? 359.128 370.341 482.093 1.00 192.35 ? 20  THR L N   1 
ATOM 1100 C CA  . THR B 2 20  ? 358.973 369.222 481.174 1.00 192.35 ? 20  THR L CA  1 
ATOM 1101 C C   . THR B 2 20  ? 358.996 367.909 481.946 1.00 192.35 ? 20  THR L C   1 
ATOM 1102 O O   . THR B 2 20  ? 359.737 367.756 482.920 1.00 192.35 ? 20  THR L O   1 
ATOM 1103 C CB  . THR B 2 20  ? 360.072 369.180 480.100 1.00 192.35 ? 20  THR L CB  1 
ATOM 1104 O OG1 . THR B 2 20  ? 361.267 368.624 480.659 1.00 192.35 ? 20  THR L OG1 1 
ATOM 1105 C CG2 . THR B 2 20  ? 360.374 370.563 479.544 1.00 192.35 ? 20  THR L CG2 1 
ATOM 1106 N N   . MET B 2 21  ? 358.174 366.961 481.496 1.00 191.80 ? 21  MET L N   1 
ATOM 1107 C CA  . MET B 2 21  ? 358.263 365.570 481.915 1.00 191.80 ? 21  MET L CA  1 
ATOM 1108 C C   . MET B 2 21  ? 358.269 364.673 480.686 1.00 191.80 ? 21  MET L C   1 
ATOM 1109 O O   . MET B 2 21  ? 357.763 365.036 479.621 1.00 191.80 ? 21  MET L O   1 
ATOM 1110 C CB  . MET B 2 21  ? 357.125 365.152 482.853 1.00 191.80 ? 21  MET L CB  1 
ATOM 1111 C CG  . MET B 2 21  ? 355.750 365.218 482.256 1.00 191.80 ? 21  MET L CG  1 
ATOM 1112 S SD  . MET B 2 21  ? 355.364 366.927 481.885 1.00 191.80 ? 21  MET L SD  1 
ATOM 1113 C CE  . MET B 2 21  ? 355.199 367.526 483.560 1.00 191.80 ? 21  MET L CE  1 
ATOM 1114 N N   . THR B 2 22  ? 358.850 363.489 480.851 1.00 187.02 ? 22  THR L N   1 
ATOM 1115 C CA  . THR B 2 22  ? 359.119 362.588 479.746 1.00 187.02 ? 22  THR L CA  1 
ATOM 1116 C C   . THR B 2 22  ? 358.401 361.261 479.943 1.00 187.02 ? 22  THR L C   1 
ATOM 1117 O O   . THR B 2 22  ? 358.069 360.866 481.063 1.00 187.02 ? 22  THR L O   1 
ATOM 1118 C CB  . THR B 2 22  ? 360.621 362.331 479.601 1.00 187.02 ? 22  THR L CB  1 
ATOM 1119 O OG1 . THR B 2 22  ? 361.191 362.117 480.898 1.00 187.02 ? 22  THR L OG1 1 
ATOM 1120 C CG2 . THR B 2 22  ? 361.303 363.516 478.946 1.00 187.02 ? 22  THR L CG2 1 
ATOM 1121 N N   . CYS B 2 23  ? 358.179 360.570 478.827 1.00 181.15 ? 23  CYS L N   1 
ATOM 1122 C CA  . CYS B 2 23  ? 357.629 359.217 478.827 1.00 181.15 ? 23  CYS L CA  1 
ATOM 1123 C C   . CYS B 2 23  ? 358.404 358.418 477.790 1.00 181.15 ? 23  CYS L C   1 
ATOM 1124 O O   . CYS B 2 23  ? 358.253 358.645 476.586 1.00 181.15 ? 23  CYS L O   1 
ATOM 1125 C CB  . CYS B 2 23  ? 356.129 359.218 478.524 1.00 181.15 ? 23  CYS L CB  1 
ATOM 1126 S SG  . CYS B 2 23  ? 355.347 357.580 478.507 1.00 181.15 ? 23  CYS L SG  1 
ATOM 1127 N N   . ARG B 2 24  ? 359.244 357.501 478.256 1.00 175.35 ? 24  ARG L N   1 
ATOM 1128 C CA  . ARG B 2 24  ? 360.100 356.698 477.398 1.00 175.35 ? 24  ARG L CA  1 
ATOM 1129 C C   . ARG B 2 24  ? 359.616 355.255 477.389 1.00 175.35 ? 24  ARG L C   1 
ATOM 1130 O O   . ARG B 2 24  ? 359.404 354.655 478.447 1.00 175.35 ? 24  ARG L O   1 
ATOM 1131 C CB  . ARG B 2 24  ? 361.552 356.763 477.872 1.00 175.35 ? 24  ARG L CB  1 
ATOM 1132 C CG  . ARG B 2 24  ? 362.480 355.747 477.225 1.00 175.35 ? 24  ARG L CG  1 
ATOM 1133 C CD  . ARG B 2 24  ? 363.935 356.026 477.560 1.00 175.35 ? 24  ARG L CD  1 
ATOM 1134 N NE  . ARG B 2 24  ? 364.462 357.174 476.829 1.00 175.35 ? 24  ARG L NE  1 
ATOM 1135 C CZ  . ARG B 2 24  ? 364.622 358.386 477.350 1.00 175.35 ? 24  ARG L CZ  1 
ATOM 1136 N NH1 . ARG B 2 24  ? 364.288 358.620 478.611 1.00 175.35 ? 24  ARG L NH1 1 
ATOM 1137 N NH2 . ARG B 2 24  ? 365.110 359.369 476.609 1.00 175.35 ? 24  ARG L NH2 1 
ATOM 1138 N N   . ALA B 2 25  ? 359.445 354.700 476.196 1.00 171.91 ? 25  ALA L N   1 
ATOM 1139 C CA  . ALA B 2 25  ? 358.923 353.353 476.042 1.00 171.91 ? 25  ALA L CA  1 
ATOM 1140 C C   . ALA B 2 25  ? 360.056 352.357 475.848 1.00 171.91 ? 25  ALA L C   1 
ATOM 1141 O O   . ALA B 2 25  ? 361.140 352.698 475.372 1.00 171.91 ? 25  ALA L O   1 
ATOM 1142 C CB  . ALA B 2 25  ? 357.957 353.280 474.861 1.00 171.91 ? 25  ALA L CB  1 
ATOM 1143 N N   . SER B 2 26  ? 359.782 351.103 476.222 1.00 171.90 ? 26  SER L N   1 
ATOM 1144 C CA  . SER B 2 26  ? 360.766 350.035 476.066 1.00 171.90 ? 26  SER L CA  1 
ATOM 1145 C C   . SER B 2 26  ? 360.900 349.588 474.616 1.00 171.90 ? 26  SER L C   1 
ATOM 1146 O O   . SER B 2 26  ? 361.878 348.924 474.260 1.00 171.90 ? 26  SER L O   1 
ATOM 1147 C CB  . SER B 2 26  ? 360.398 348.840 476.943 1.00 171.90 ? 26  SER L CB  1 
ATOM 1148 O OG  . SER B 2 26  ? 361.299 347.770 476.736 1.00 171.90 ? 26  SER L OG  1 
ATOM 1149 N N   . SER B 2 27  ? 359.925 349.921 473.777 1.00 175.64 ? 27  SER L N   1 
ATOM 1150 C CA  . SER B 2 27  ? 359.953 349.624 472.352 1.00 175.64 ? 27  SER L CA  1 
ATOM 1151 C C   . SER B 2 27  ? 359.601 350.887 471.569 1.00 175.64 ? 27  SER L C   1 
ATOM 1152 O O   . SER B 2 27  ? 359.516 351.985 472.123 1.00 175.64 ? 27  SER L O   1 
ATOM 1153 C CB  . SER B 2 27  ? 358.999 348.475 472.015 1.00 175.64 ? 27  SER L CB  1 
ATOM 1154 O OG  . SER B 2 27  ? 359.043 348.158 470.635 1.00 175.64 ? 27  SER L OG  1 
ATOM 1155 N N   . SER B 2 28  ? 359.403 350.721 470.264 1.00 174.03 ? 28  SER L N   1 
ATOM 1156 C CA  . SER B 2 28  ? 359.047 351.834 469.390 1.00 174.03 ? 28  SER L CA  1 
ATOM 1157 C C   . SER B 2 28  ? 357.531 351.902 469.240 1.00 174.03 ? 28  SER L C   1 
ATOM 1158 O O   . SER B 2 28  ? 356.954 351.198 468.405 1.00 174.03 ? 28  SER L O   1 
ATOM 1159 C CB  . SER B 2 28  ? 359.718 351.670 468.027 1.00 174.03 ? 28  SER L CB  1 
ATOM 1160 O OG  . SER B 2 28  ? 359.762 352.895 467.321 1.00 174.03 ? 28  SER L OG  1 
ATOM 1161 N N   . VAL B 2 29  ? 356.887 352.754 470.035 1.00 165.62 ? 29  VAL L N   1 
ATOM 1162 C CA  . VAL B 2 29  ? 355.434 352.869 470.049 1.00 165.62 ? 29  VAL L CA  1 
ATOM 1163 C C   . VAL B 2 29  ? 355.036 353.990 469.098 1.00 165.62 ? 29  VAL L C   1 
ATOM 1164 O O   . VAL B 2 29  ? 355.807 354.932 468.873 1.00 165.62 ? 29  VAL L O   1 
ATOM 1165 C CB  . VAL B 2 29  ? 354.901 353.088 471.483 1.00 165.62 ? 29  VAL L CB  1 
ATOM 1166 C CG1 . VAL B 2 29  ? 355.152 354.498 471.987 1.00 165.62 ? 29  VAL L CG1 1 
ATOM 1167 C CG2 . VAL B 2 29  ? 353.430 352.728 471.582 1.00 165.62 ? 29  VAL L CG2 1 
ATOM 1168 N N   . SER B 2 30  ? 353.864 353.848 468.483 1.00 163.74 ? 30  SER L N   1 
ATOM 1169 C CA  . SER B 2 30  ? 353.400 354.817 467.501 1.00 163.74 ? 30  SER L CA  1 
ATOM 1170 C C   . SER B 2 30  ? 352.981 356.118 468.169 1.00 163.74 ? 30  SER L C   1 
ATOM 1171 O O   . SER B 2 30  ? 352.596 356.148 469.340 1.00 163.74 ? 30  SER L O   1 
ATOM 1172 C CB  . SER B 2 30  ? 352.223 354.260 466.708 1.00 163.74 ? 30  SER L CB  1 
ATOM 1173 O OG  . SER B 2 30  ? 351.444 355.319 466.181 1.00 163.74 ? 30  SER L OG  1 
ATOM 1174 N N   . SER B 2 31  ? 353.042 357.203 467.399 1.00 159.59 ? 31  SER L N   1 
ATOM 1175 C CA  . SER B 2 31  ? 352.632 358.505 467.902 1.00 159.59 ? 31  SER L CA  1 
ATOM 1176 C C   . SER B 2 31  ? 351.123 358.628 468.053 1.00 159.59 ? 31  SER L C   1 
ATOM 1177 O O   . SER B 2 31  ? 350.656 359.527 468.759 1.00 159.59 ? 31  SER L O   1 
ATOM 1178 C CB  . SER B 2 31  ? 353.137 359.607 466.975 1.00 159.59 ? 31  SER L CB  1 
ATOM 1179 O OG  . SER B 2 31  ? 352.897 359.263 465.623 1.00 159.59 ? 31  SER L OG  1 
ATOM 1180 N N   . SER B 2 32  ? 350.357 357.751 467.413 1.00 156.50 ? 32  SER L N   1 
ATOM 1181 C CA  . SER B 2 32  ? 348.904 357.796 467.472 1.00 156.50 ? 32  SER L CA  1 
ATOM 1182 C C   . SER B 2 32  ? 348.329 356.954 468.598 1.00 156.50 ? 32  SER L C   1 
ATOM 1183 O O   . SER B 2 32  ? 347.108 356.935 468.773 1.00 156.50 ? 32  SER L O   1 
ATOM 1184 C CB  . SER B 2 32  ? 348.312 357.326 466.144 1.00 156.50 ? 32  SER L CB  1 
ATOM 1185 O OG  . SER B 2 32  ? 348.997 356.182 465.670 1.00 156.50 ? 32  SER L OG  1 
ATOM 1186 N N   . TYR B 2 33  ? 349.169 356.262 469.364 1.00 155.39 ? 33  TYR L N   1 
ATOM 1187 C CA  . TYR B 2 33  ? 348.694 355.353 470.396 1.00 155.39 ? 33  TYR L CA  1 
ATOM 1188 C C   . TYR B 2 33  ? 349.224 355.715 471.774 1.00 155.39 ? 33  TYR L C   1 
ATOM 1189 O O   . TYR B 2 33  ? 349.316 354.844 472.642 1.00 155.39 ? 33  TYR L O   1 
ATOM 1190 C CB  . TYR B 2 33  ? 349.075 353.914 470.051 1.00 155.39 ? 33  TYR L CB  1 
ATOM 1191 C CG  . TYR B 2 33  ? 348.227 353.306 468.961 1.00 155.39 ? 33  TYR L CG  1 
ATOM 1192 C CD1 . TYR B 2 33  ? 346.902 353.688 468.796 1.00 155.39 ? 33  TYR L CD1 1 
ATOM 1193 C CD2 . TYR B 2 33  ? 348.751 352.356 468.092 1.00 155.39 ? 33  TYR L CD2 1 
ATOM 1194 C CE1 . TYR B 2 33  ? 346.122 353.143 467.804 1.00 155.39 ? 33  TYR L CE1 1 
ATOM 1195 C CE2 . TYR B 2 33  ? 347.977 351.804 467.094 1.00 155.39 ? 33  TYR L CE2 1 
ATOM 1196 C CZ  . TYR B 2 33  ? 346.662 352.203 466.958 1.00 155.39 ? 33  TYR L CZ  1 
ATOM 1197 O OH  . TYR B 2 33  ? 345.876 351.663 465.970 1.00 155.39 ? 33  TYR L OH  1 
ATOM 1198 N N   . LEU B 2 34  ? 349.575 356.977 472.001 1.00 165.45 ? 34  LEU L N   1 
ATOM 1199 C CA  . LEU B 2 34  ? 350.102 357.422 473.286 1.00 165.45 ? 34  LEU L CA  1 
ATOM 1200 C C   . LEU B 2 34  ? 349.341 358.662 473.729 1.00 165.45 ? 34  LEU L C   1 
ATOM 1201 O O   . LEU B 2 34  ? 349.232 359.632 472.973 1.00 165.45 ? 34  LEU L O   1 
ATOM 1202 C CB  . LEU B 2 34  ? 351.603 357.701 473.201 1.00 165.45 ? 34  LEU L CB  1 
ATOM 1203 C CG  . LEU B 2 34  ? 352.378 357.849 474.510 1.00 165.45 ? 34  LEU L CG  1 
ATOM 1204 C CD1 . LEU B 2 34  ? 353.712 357.144 474.382 1.00 165.45 ? 34  LEU L CD1 1 
ATOM 1205 C CD2 . LEU B 2 34  ? 352.597 359.308 474.863 1.00 165.45 ? 34  LEU L CD2 1 
ATOM 1206 N N   . HIS B 2 35  ? 348.816 358.627 474.947 1.00 166.53 ? 35  HIS L N   1 
ATOM 1207 C CA  . HIS B 2 35  ? 347.989 359.695 475.480 1.00 166.53 ? 35  HIS L CA  1 
ATOM 1208 C C   . HIS B 2 35  ? 348.463 360.062 476.878 1.00 166.53 ? 35  HIS L C   1 
ATOM 1209 O O   . HIS B 2 35  ? 349.278 359.368 477.487 1.00 166.53 ? 35  HIS L O   1 
ATOM 1210 C CB  . HIS B 2 35  ? 346.515 359.281 475.511 1.00 166.53 ? 35  HIS L CB  1 
ATOM 1211 C CG  . HIS B 2 35  ? 346.115 358.401 474.372 1.00 166.53 ? 35  HIS L CG  1 
ATOM 1212 N ND1 . HIS B 2 35  ? 346.173 358.814 473.060 1.00 166.53 ? 35  HIS L ND1 1 
ATOM 1213 C CD2 . HIS B 2 35  ? 345.680 357.120 474.345 1.00 166.53 ? 35  HIS L CD2 1 
ATOM 1214 C CE1 . HIS B 2 35  ? 345.774 357.831 472.274 1.00 166.53 ? 35  HIS L CE1 1 
ATOM 1215 N NE2 . HIS B 2 35  ? 345.466 356.793 473.029 1.00 166.53 ? 35  HIS L NE2 1 
ATOM 1216 N N   . TRP B 2 36  ? 347.936 361.170 477.388 1.00 173.81 ? 36  TRP L N   1 
ATOM 1217 C CA  . TRP B 2 36  ? 348.282 361.658 478.713 1.00 173.81 ? 36  TRP L CA  1 
ATOM 1218 C C   . TRP B 2 36  ? 347.025 361.800 479.553 1.00 173.81 ? 36  TRP L C   1 
ATOM 1219 O O   . TRP B 2 36  ? 345.937 362.041 479.025 1.00 173.81 ? 36  TRP L O   1 
ATOM 1220 C CB  . TRP B 2 36  ? 348.993 363.002 478.640 1.00 173.81 ? 36  TRP L CB  1 
ATOM 1221 C CG  . TRP B 2 36  ? 350.407 362.926 478.190 1.00 173.81 ? 36  TRP L CG  1 
ATOM 1222 C CD1 . TRP B 2 36  ? 350.884 363.223 476.953 1.00 173.81 ? 36  TRP L CD1 1 
ATOM 1223 C CD2 . TRP B 2 36  ? 351.539 362.554 478.980 1.00 173.81 ? 36  TRP L CD2 1 
ATOM 1224 N NE1 . TRP B 2 36  ? 352.244 363.053 476.918 1.00 173.81 ? 36  TRP L NE1 1 
ATOM 1225 C CE2 . TRP B 2 36  ? 352.671 362.643 478.152 1.00 173.81 ? 36  TRP L CE2 1 
ATOM 1226 C CE3 . TRP B 2 36  ? 351.706 362.152 480.306 1.00 173.81 ? 36  TRP L CE3 1 
ATOM 1227 C CZ2 . TRP B 2 36  ? 353.950 362.342 478.603 1.00 173.81 ? 36  TRP L CZ2 1 
ATOM 1228 C CZ3 . TRP B 2 36  ? 352.976 361.856 480.753 1.00 173.81 ? 36  TRP L CZ3 1 
ATOM 1229 C CH2 . TRP B 2 36  ? 354.082 361.950 479.904 1.00 173.81 ? 36  TRP L CH2 1 
ATOM 1230 N N   . TYR B 2 37  ? 347.181 361.660 480.862 1.00 172.13 ? 37  TYR L N   1 
ATOM 1231 C CA  . TYR B 2 37  ? 346.089 361.832 481.802 1.00 172.13 ? 37  TYR L CA  1 
ATOM 1232 C C   . TYR B 2 37  ? 346.531 362.740 482.938 1.00 172.13 ? 37  TYR L C   1 
ATOM 1233 O O   . TYR B 2 37  ? 347.711 363.065 483.084 1.00 172.13 ? 37  TYR L O   1 
ATOM 1234 C CB  . TYR B 2 37  ? 345.622 360.484 482.361 1.00 172.13 ? 37  TYR L CB  1 
ATOM 1235 C CG  . TYR B 2 37  ? 345.035 359.551 481.331 1.00 172.13 ? 37  TYR L CG  1 
ATOM 1236 C CD1 . TYR B 2 37  ? 343.710 359.670 480.934 1.00 172.13 ? 37  TYR L CD1 1 
ATOM 1237 C CD2 . TYR B 2 37  ? 345.800 358.541 480.766 1.00 172.13 ? 37  TYR L CD2 1 
ATOM 1238 C CE1 . TYR B 2 37  ? 343.168 358.814 479.998 1.00 172.13 ? 37  TYR L CE1 1 
ATOM 1239 C CE2 . TYR B 2 37  ? 345.266 357.681 479.827 1.00 172.13 ? 37  TYR L CE2 1 
ATOM 1240 C CZ  . TYR B 2 37  ? 343.951 357.823 479.448 1.00 172.13 ? 37  TYR L CZ  1 
ATOM 1241 O OH  . TYR B 2 37  ? 343.415 356.970 478.515 1.00 172.13 ? 37  TYR L OH  1 
ATOM 1242 N N   . GLN B 2 38  ? 345.561 363.154 483.748 1.00 176.63 ? 38  GLN L N   1 
ATOM 1243 C CA  . GLN B 2 38  ? 345.834 363.903 484.969 1.00 176.63 ? 38  GLN L CA  1 
ATOM 1244 C C   . GLN B 2 38  ? 344.841 363.464 486.029 1.00 176.63 ? 38  GLN L C   1 
ATOM 1245 O O   . GLN B 2 38  ? 343.638 363.397 485.763 1.00 176.63 ? 38  GLN L O   1 
ATOM 1246 C CB  . GLN B 2 38  ? 345.745 365.413 484.745 1.00 176.63 ? 38  GLN L CB  1 
ATOM 1247 C CG  . GLN B 2 38  ? 346.149 366.223 485.964 1.00 176.63 ? 38  GLN L CG  1 
ATOM 1248 C CD  . GLN B 2 38  ? 346.051 367.712 485.733 1.00 176.63 ? 38  GLN L CD  1 
ATOM 1249 O OE1 . GLN B 2 38  ? 345.096 368.194 485.130 1.00 176.63 ? 38  GLN L OE1 1 
ATOM 1250 N NE2 . GLN B 2 38  ? 347.039 368.451 486.217 1.00 176.63 ? 38  GLN L NE2 1 
ATOM 1251 N N   . GLN B 2 39  ? 345.345 363.162 487.219 1.00 184.68 ? 39  GLN L N   1 
ATOM 1252 C CA  . GLN B 2 39  ? 344.525 362.723 488.338 1.00 184.68 ? 39  GLN L CA  1 
ATOM 1253 C C   . GLN B 2 39  ? 344.833 363.599 489.540 1.00 184.68 ? 39  GLN L C   1 
ATOM 1254 O O   . GLN B 2 39  ? 345.992 363.704 489.954 1.00 184.68 ? 39  GLN L O   1 
ATOM 1255 C CB  . GLN B 2 39  ? 344.785 361.256 488.668 1.00 184.68 ? 39  GLN L CB  1 
ATOM 1256 C CG  . GLN B 2 39  ? 343.862 360.710 489.729 1.00 184.68 ? 39  GLN L CG  1 
ATOM 1257 C CD  . GLN B 2 39  ? 344.375 359.428 490.334 1.00 184.68 ? 39  GLN L CD  1 
ATOM 1258 O OE1 . GLN B 2 39  ? 345.583 359.196 490.387 1.00 184.68 ? 39  GLN L OE1 1 
ATOM 1259 N NE2 . GLN B 2 39  ? 343.462 358.583 490.795 1.00 184.68 ? 39  GLN L NE2 1 
ATOM 1260 N N   . LYS B 2 40  ? 343.798 364.214 490.104 1.00 188.83 ? 40  LYS L N   1 
ATOM 1261 C CA  . LYS B 2 40  ? 343.971 365.071 491.264 1.00 188.83 ? 40  LYS L CA  1 
ATOM 1262 C C   . LYS B 2 40  ? 344.055 364.230 492.536 1.00 188.83 ? 40  LYS L C   1 
ATOM 1263 O O   . LYS B 2 40  ? 344.119 362.999 492.499 1.00 188.83 ? 40  LYS L O   1 
ATOM 1264 C CB  . LYS B 2 40  ? 342.836 366.089 491.346 1.00 188.83 ? 40  LYS L CB  1 
ATOM 1265 C CG  . LYS B 2 40  ? 342.754 367.040 490.157 1.00 188.83 ? 40  LYS L CG  1 
ATOM 1266 C CD  . LYS B 2 40  ? 344.011 367.887 489.972 1.00 188.83 ? 40  LYS L CD  1 
ATOM 1267 C CE  . LYS B 2 40  ? 344.377 368.694 491.217 1.00 188.83 ? 40  LYS L CE  1 
ATOM 1268 N NZ  . LYS B 2 40  ? 345.478 369.659 490.950 1.00 188.83 ? 40  LYS L NZ  1 
ATOM 1269 N N   . SER B 2 41  ? 344.045 364.908 493.683 1.00 192.92 ? 41  SER L N   1 
ATOM 1270 C CA  . SER B 2 41  ? 344.256 364.249 494.970 1.00 192.92 ? 41  SER L CA  1 
ATOM 1271 C C   . SER B 2 41  ? 343.030 363.427 495.344 1.00 192.92 ? 41  SER L C   1 
ATOM 1272 O O   . SER B 2 41  ? 342.097 363.938 495.972 1.00 192.92 ? 41  SER L O   1 
ATOM 1273 C CB  . SER B 2 41  ? 344.558 365.286 496.045 1.00 192.92 ? 41  SER L CB  1 
ATOM 1274 O OG  . SER B 2 41  ? 344.265 364.771 497.331 1.00 192.92 ? 41  SER L OG  1 
ATOM 1275 N N   . GLY B 2 42  ? 343.041 362.150 494.973 1.00 193.15 ? 42  GLY L N   1 
ATOM 1276 C CA  . GLY B 2 42  ? 341.913 361.281 495.242 1.00 193.15 ? 42  GLY L CA  1 
ATOM 1277 C C   . GLY B 2 42  ? 340.695 361.562 494.393 1.00 193.15 ? 42  GLY L C   1 
ATOM 1278 O O   . GLY B 2 42  ? 339.567 361.348 494.848 1.00 193.15 ? 42  GLY L O   1 
ATOM 1279 N N   . ALA B 2 43  ? 340.890 362.034 493.166 1.00 189.78 ? 43  ALA L N   1 
ATOM 1280 C CA  . ALA B 2 43  ? 339.793 362.367 492.273 1.00 189.78 ? 43  ALA L CA  1 
ATOM 1281 C C   . ALA B 2 43  ? 339.837 361.454 491.057 1.00 189.78 ? 43  ALA L C   1 
ATOM 1282 O O   . ALA B 2 43  ? 340.752 360.644 490.888 1.00 189.78 ? 43  ALA L O   1 
ATOM 1283 C CB  . ALA B 2 43  ? 339.846 363.837 491.841 1.00 189.78 ? 43  ALA L CB  1 
ATOM 1284 N N   . SER B 2 44  ? 338.822 361.587 490.210 1.00 183.71 ? 44  SER L N   1 
ATOM 1285 C CA  . SER B 2 44  ? 338.756 360.787 489.002 1.00 183.71 ? 44  SER L CA  1 
ATOM 1286 C C   . SER B 2 44  ? 339.793 361.273 487.992 1.00 183.71 ? 44  SER L C   1 
ATOM 1287 O O   . SER B 2 44  ? 339.986 362.479 487.819 1.00 183.71 ? 44  SER L O   1 
ATOM 1288 C CB  . SER B 2 44  ? 337.360 360.861 488.392 1.00 183.71 ? 44  SER L CB  1 
ATOM 1289 O OG  . SER B 2 44  ? 336.390 360.325 489.274 1.00 183.71 ? 44  SER L OG  1 
ATOM 1290 N N   . PRO B 2 45  ? 340.489 360.356 487.327 1.00 179.02 ? 45  PRO L N   1 
ATOM 1291 C CA  . PRO B 2 45  ? 341.462 360.764 486.311 1.00 179.02 ? 45  PRO L CA  1 
ATOM 1292 C C   . PRO B 2 45  ? 340.774 361.284 485.062 1.00 179.02 ? 45  PRO L C   1 
ATOM 1293 O O   . PRO B 2 45  ? 339.705 360.822 484.662 1.00 179.02 ? 45  PRO L O   1 
ATOM 1294 C CB  . PRO B 2 45  ? 342.236 359.476 486.019 1.00 179.02 ? 45  PRO L CB  1 
ATOM 1295 C CG  . PRO B 2 45  ? 341.955 358.584 487.186 1.00 179.02 ? 45  PRO L CG  1 
ATOM 1296 C CD  . PRO B 2 45  ? 340.567 358.917 487.610 1.00 179.02 ? 45  PRO L CD  1 
ATOM 1297 N N   . LYS B 2 46  ? 341.420 362.262 484.438 1.00 172.08 ? 46  LYS L N   1 
ATOM 1298 C CA  . LYS B 2 46  ? 340.859 362.955 483.292 1.00 172.08 ? 46  LYS L CA  1 
ATOM 1299 C C   . LYS B 2 46  ? 341.896 362.986 482.182 1.00 172.08 ? 46  LYS L C   1 
ATOM 1300 O O   . LYS B 2 46  ? 343.089 363.163 482.437 1.00 172.08 ? 46  LYS L O   1 
ATOM 1301 C CB  . LYS B 2 46  ? 340.432 364.382 483.666 1.00 172.08 ? 46  LYS L CB  1 
ATOM 1302 C CG  . LYS B 2 46  ? 339.778 365.180 482.550 1.00 172.08 ? 46  LYS L CG  1 
ATOM 1303 C CD  . LYS B 2 46  ? 338.558 365.932 483.051 1.00 172.08 ? 46  LYS L CD  1 
ATOM 1304 C CE  . LYS B 2 46  ? 338.937 366.955 484.106 1.00 172.08 ? 46  LYS L CE  1 
ATOM 1305 N NZ  . LYS B 2 46  ? 337.790 367.834 484.455 1.00 172.08 ? 46  LYS L NZ  1 
ATOM 1306 N N   . LEU B 2 47  ? 341.432 362.786 480.951 1.00 167.45 ? 47  LEU L N   1 
ATOM 1307 C CA  . LEU B 2 47  ? 342.304 362.897 479.792 1.00 167.45 ? 47  LEU L CA  1 
ATOM 1308 C C   . LEU B 2 47  ? 342.741 364.346 479.626 1.00 167.45 ? 47  LEU L C   1 
ATOM 1309 O O   . LEU B 2 47  ? 341.942 365.270 479.796 1.00 167.45 ? 47  LEU L O   1 
ATOM 1310 C CB  . LEU B 2 47  ? 341.577 362.400 478.542 1.00 167.45 ? 47  LEU L CB  1 
ATOM 1311 C CG  . LEU B 2 47  ? 342.292 361.991 477.245 1.00 167.45 ? 47  LEU L CG  1 
ATOM 1312 C CD1 . LEU B 2 47  ? 341.291 361.278 476.395 1.00 167.45 ? 47  LEU L CD1 1 
ATOM 1313 C CD2 . LEU B 2 47  ? 342.889 363.129 476.423 1.00 167.45 ? 47  LEU L CD2 1 
ATOM 1314 N N   . TRP B 2 48  ? 344.014 364.543 479.296 1.00 171.24 ? 48  TRP L N   1 
ATOM 1315 C CA  . TRP B 2 48  ? 344.562 365.874 479.088 1.00 171.24 ? 48  TRP L CA  1 
ATOM 1316 C C   . TRP B 2 48  ? 345.054 366.067 477.661 1.00 171.24 ? 48  TRP L C   1 
ATOM 1317 O O   . TRP B 2 48  ? 344.671 367.036 477.002 1.00 171.24 ? 48  TRP L O   1 
ATOM 1318 C CB  . TRP B 2 48  ? 345.688 366.125 480.099 1.00 171.24 ? 48  TRP L CB  1 
ATOM 1319 C CG  . TRP B 2 48  ? 345.706 367.509 480.661 1.00 171.24 ? 48  TRP L CG  1 
ATOM 1320 C CD1 . TRP B 2 48  ? 346.669 368.451 480.482 1.00 171.24 ? 48  TRP L CD1 1 
ATOM 1321 C CD2 . TRP B 2 48  ? 344.710 368.109 481.495 1.00 171.24 ? 48  TRP L CD2 1 
ATOM 1322 N NE1 . TRP B 2 48  ? 346.342 369.597 481.153 1.00 171.24 ? 48  TRP L NE1 1 
ATOM 1323 C CE2 . TRP B 2 48  ? 345.140 369.415 481.781 1.00 171.24 ? 48  TRP L CE2 1 
ATOM 1324 C CE3 . TRP B 2 48  ? 343.498 367.668 482.029 1.00 171.24 ? 48  TRP L CE3 1 
ATOM 1325 C CZ2 . TRP B 2 48  ? 344.403 370.285 482.573 1.00 171.24 ? 48  TRP L CZ2 1 
ATOM 1326 C CZ3 . TRP B 2 48  ? 342.767 368.533 482.814 1.00 171.24 ? 48  TRP L CZ3 1 
ATOM 1327 C CH2 . TRP B 2 48  ? 343.220 369.827 483.078 1.00 171.24 ? 48  TRP L CH2 1 
ATOM 1328 N N   . ILE B 2 49  ? 345.901 365.170 477.160 1.00 166.85 ? 49  ILE L N   1 
ATOM 1329 C CA  . ILE B 2 49  ? 346.411 365.229 475.793 1.00 166.85 ? 49  ILE L CA  1 
ATOM 1330 C C   . ILE B 2 49  ? 346.289 363.840 475.187 1.00 166.85 ? 49  ILE L C   1 
ATOM 1331 O O   . ILE B 2 49  ? 346.791 362.867 475.761 1.00 166.85 ? 49  ILE L O   1 
ATOM 1332 C CB  . ILE B 2 49  ? 347.873 365.714 475.711 1.00 166.85 ? 49  ILE L CB  1 
ATOM 1333 C CG1 . ILE B 2 49  ? 348.056 367.125 476.280 1.00 166.85 ? 49  ILE L CG1 1 
ATOM 1334 C CG2 . ILE B 2 49  ? 348.376 365.677 474.276 1.00 166.85 ? 49  ILE L CG2 1 
ATOM 1335 C CD1 . ILE B 2 49  ? 348.456 367.187 477.731 1.00 166.85 ? 49  ILE L CD1 1 
ATOM 1336 N N   . TYR B 2 50  ? 345.636 363.746 474.032 1.00 163.01 ? 50  TYR L N   1 
ATOM 1337 C CA  . TYR B 2 50  ? 345.541 362.494 473.301 1.00 163.01 ? 50  TYR L CA  1 
ATOM 1338 C C   . TYR B 2 50  ? 346.334 362.576 472.005 1.00 163.01 ? 50  TYR L C   1 
ATOM 1339 O O   . TYR B 2 50  ? 346.418 363.636 471.379 1.00 163.01 ? 50  TYR L O   1 
ATOM 1340 C CB  . TYR B 2 50  ? 344.081 362.127 473.012 1.00 163.01 ? 50  TYR L CB  1 
ATOM 1341 C CG  . TYR B 2 50  ? 343.382 362.976 471.975 1.00 163.01 ? 50  TYR L CG  1 
ATOM 1342 C CD1 . TYR B 2 50  ? 342.853 364.212 472.307 1.00 163.01 ? 50  TYR L CD1 1 
ATOM 1343 C CD2 . TYR B 2 50  ? 343.218 362.521 470.672 1.00 163.01 ? 50  TYR L CD2 1 
ATOM 1344 C CE1 . TYR B 2 50  ? 342.199 364.982 471.367 1.00 163.01 ? 50  TYR L CE1 1 
ATOM 1345 C CE2 . TYR B 2 50  ? 342.575 363.287 469.725 1.00 163.01 ? 50  TYR L CE2 1 
ATOM 1346 C CZ  . TYR B 2 50  ? 342.062 364.512 470.080 1.00 163.01 ? 50  TYR L CZ  1 
ATOM 1347 O OH  . TYR B 2 50  ? 341.420 365.276 469.138 1.00 163.01 ? 50  TYR L OH  1 
ATOM 1348 N N   . SER B 2 51  ? 346.930 361.433 471.634 1.00 163.02 ? 51  SER L N   1 
ATOM 1349 C CA  . SER B 2 51  ? 347.720 361.247 470.407 1.00 163.02 ? 51  SER L CA  1 
ATOM 1350 C C   . SER B 2 51  ? 348.909 362.202 470.336 1.00 163.02 ? 51  SER L C   1 
ATOM 1351 O O   . SER B 2 51  ? 349.290 362.664 469.260 1.00 163.02 ? 51  SER L O   1 
ATOM 1352 C CB  . SER B 2 51  ? 346.855 361.364 469.151 1.00 163.02 ? 51  SER L CB  1 
ATOM 1353 O OG  . SER B 2 51  ? 347.515 360.793 468.037 1.00 163.02 ? 51  SER L OG  1 
ATOM 1354 N N   . THR B 2 52  ? 349.460 362.541 471.509 1.00 168.63 ? 52  THR L N   1 
ATOM 1355 C CA  . THR B 2 52  ? 350.725 363.248 471.740 1.00 168.63 ? 52  THR L CA  1 
ATOM 1356 C C   . THR B 2 52  ? 350.782 364.690 471.239 1.00 168.63 ? 52  THR L C   1 
ATOM 1357 O O   . THR B 2 52  ? 351.764 365.388 471.506 1.00 168.63 ? 52  THR L O   1 
ATOM 1358 C CB  . THR B 2 52  ? 351.922 362.490 471.141 1.00 168.63 ? 52  THR L CB  1 
ATOM 1359 O OG1 . THR B 2 52  ? 351.927 362.633 469.715 1.00 168.63 ? 52  THR L OG1 1 
ATOM 1360 C CG2 . THR B 2 52  ? 351.921 361.014 471.532 1.00 168.63 ? 52  THR L CG2 1 
ATOM 1361 N N   . SER B 2 53  ? 349.767 365.156 470.519 1.00 168.37 ? 53  SER L N   1 
ATOM 1362 C CA  . SER B 2 53  ? 349.776 366.528 470.038 1.00 168.37 ? 53  SER L CA  1 
ATOM 1363 C C   . SER B 2 53  ? 348.437 367.234 470.158 1.00 168.37 ? 53  SER L C   1 
ATOM 1364 O O   . SER B 2 53  ? 348.391 368.457 470.001 1.00 168.37 ? 53  SER L O   1 
ATOM 1365 C CB  . SER B 2 53  ? 350.232 366.567 468.572 1.00 168.37 ? 53  SER L CB  1 
ATOM 1366 O OG  . SER B 2 53  ? 349.593 365.550 467.822 1.00 168.37 ? 53  SER L OG  1 
ATOM 1367 N N   . ASN B 2 54  ? 347.356 366.518 470.432 1.00 168.58 ? 54  ASN L N   1 
ATOM 1368 C CA  . ASN B 2 54  ? 346.018 367.082 470.400 1.00 168.58 ? 54  ASN L CA  1 
ATOM 1369 C C   . ASN B 2 54  ? 345.497 367.232 471.820 1.00 168.58 ? 54  ASN L C   1 
ATOM 1370 O O   . ASN B 2 54  ? 345.432 366.257 472.574 1.00 168.58 ? 54  ASN L O   1 
ATOM 1371 C CB  . ASN B 2 54  ? 345.070 366.198 469.584 1.00 168.58 ? 54  ASN L CB  1 
ATOM 1372 C CG  . ASN B 2 54  ? 345.572 365.932 468.175 1.00 168.58 ? 54  ASN L CG  1 
ATOM 1373 O OD1 . ASN B 2 54  ? 346.639 366.394 467.782 1.00 168.58 ? 54  ASN L OD1 1 
ATOM 1374 N ND2 . ASN B 2 54  ? 344.800 365.171 467.411 1.00 168.58 ? 54  ASN L ND2 1 
ATOM 1375 N N   . LEU B 2 55  ? 345.135 368.457 472.181 1.00 172.31 ? 55  LEU L N   1 
ATOM 1376 C CA  . LEU B 2 55  ? 344.604 368.726 473.507 1.00 172.31 ? 55  LEU L CA  1 
ATOM 1377 C C   . LEU B 2 55  ? 343.191 368.173 473.630 1.00 172.31 ? 55  LEU L C   1 
ATOM 1378 O O   . LEU B 2 55  ? 342.500 367.948 472.634 1.00 172.31 ? 55  LEU L O   1 
ATOM 1379 C CB  . LEU B 2 55  ? 344.595 370.227 473.799 1.00 172.31 ? 55  LEU L CB  1 
ATOM 1380 C CG  . LEU B 2 55  ? 345.835 370.945 474.353 1.00 172.31 ? 55  LEU L CG  1 
ATOM 1381 C CD1 . LEU B 2 55  ? 346.230 370.386 475.708 1.00 172.31 ? 55  LEU L CD1 1 
ATOM 1382 C CD2 . LEU B 2 55  ? 347.015 370.931 473.391 1.00 172.31 ? 55  LEU L CD2 1 
ATOM 1383 N N   . ALA B 2 56  ? 342.761 367.963 474.868 1.00 172.59 ? 56  ALA L N   1 
ATOM 1384 C CA  . ALA B 2 56  ? 341.428 367.440 475.130 1.00 172.59 ? 56  ALA L CA  1 
ATOM 1385 C C   . ALA B 2 56  ? 340.419 368.587 475.116 1.00 172.59 ? 56  ALA L C   1 
ATOM 1386 O O   . ALA B 2 56  ? 340.731 369.722 474.748 1.00 172.59 ? 56  ALA L O   1 
ATOM 1387 C CB  . ALA B 2 56  ? 341.407 366.676 476.450 1.00 172.59 ? 56  ALA L CB  1 
ATOM 1388 N N   . SER B 2 57  ? 339.187 368.298 475.521 1.00 176.46 ? 57  SER L N   1 
ATOM 1389 C CA  . SER B 2 57  ? 338.136 369.304 475.573 1.00 176.46 ? 57  SER L CA  1 
ATOM 1390 C C   . SER B 2 57  ? 338.059 369.893 476.974 1.00 176.46 ? 57  SER L C   1 
ATOM 1391 O O   . SER B 2 57  ? 337.861 369.165 477.951 1.00 176.46 ? 57  SER L O   1 
ATOM 1392 C CB  . SER B 2 57  ? 336.789 368.699 475.180 1.00 176.46 ? 57  SER L CB  1 
ATOM 1393 O OG  . SER B 2 57  ? 336.896 367.950 473.983 1.00 176.46 ? 57  SER L OG  1 
ATOM 1394 N N   . GLY B 2 58  ? 338.220 371.210 477.068 1.00 177.52 ? 58  GLY L N   1 
ATOM 1395 C CA  . GLY B 2 58  ? 338.130 371.881 478.346 1.00 177.52 ? 58  GLY L CA  1 
ATOM 1396 C C   . GLY B 2 58  ? 339.441 372.079 479.070 1.00 177.52 ? 58  GLY L C   1 
ATOM 1397 O O   . GLY B 2 58  ? 339.440 372.161 480.303 1.00 177.52 ? 58  GLY L O   1 
ATOM 1398 N N   . VAL B 2 59  ? 340.557 372.149 478.353 1.00 176.42 ? 59  VAL L N   1 
ATOM 1399 C CA  . VAL B 2 59  ? 341.860 372.353 478.977 1.00 176.42 ? 59  VAL L CA  1 
ATOM 1400 C C   . VAL B 2 59  ? 342.425 373.696 478.533 1.00 176.42 ? 59  VAL L C   1 
ATOM 1401 O O   . VAL B 2 59  ? 342.105 374.163 477.430 1.00 176.42 ? 59  VAL L O   1 
ATOM 1402 C CB  . VAL B 2 59  ? 342.818 371.205 478.633 1.00 176.42 ? 59  VAL L CB  1 
ATOM 1403 C CG1 . VAL B 2 59  ? 342.456 369.976 479.434 1.00 176.42 ? 59  VAL L CG1 1 
ATOM 1404 C CG2 . VAL B 2 59  ? 342.758 370.906 477.150 1.00 176.42 ? 59  VAL L CG2 1 
ATOM 1405 N N   . PRO B 2 60  ? 343.236 374.360 479.356 1.00 178.59 ? 60  PRO L N   1 
ATOM 1406 C CA  . PRO B 2 60  ? 343.924 375.574 478.900 1.00 178.59 ? 60  PRO L CA  1 
ATOM 1407 C C   . PRO B 2 60  ? 344.962 375.271 477.829 1.00 178.59 ? 60  PRO L C   1 
ATOM 1408 O O   . PRO B 2 60  ? 345.417 374.138 477.659 1.00 178.59 ? 60  PRO L O   1 
ATOM 1409 C CB  . PRO B 2 60  ? 344.586 376.108 480.174 1.00 178.59 ? 60  PRO L CB  1 
ATOM 1410 C CG  . PRO B 2 60  ? 343.787 375.524 481.290 1.00 178.59 ? 60  PRO L CG  1 
ATOM 1411 C CD  . PRO B 2 60  ? 343.350 374.175 480.812 1.00 178.59 ? 60  PRO L CD  1 
ATOM 1412 N N   . ALA B 2 61  ? 345.342 376.317 477.102 1.00 178.30 ? 61  ALA L N   1 
ATOM 1413 C CA  . ALA B 2 61  ? 346.182 376.176 475.922 1.00 178.30 ? 61  ALA L CA  1 
ATOM 1414 C C   . ALA B 2 61  ? 347.672 376.223 476.231 1.00 178.30 ? 61  ALA L C   1 
ATOM 1415 O O   . ALA B 2 61  ? 348.477 376.327 475.302 1.00 178.30 ? 61  ALA L O   1 
ATOM 1416 C CB  . ALA B 2 61  ? 345.838 377.260 474.899 1.00 178.30 ? 61  ALA L CB  1 
ATOM 1417 N N   . ARG B 2 62  ? 348.061 376.153 477.501 1.00 183.61 ? 62  ARG L N   1 
ATOM 1418 C CA  . ARG B 2 62  ? 349.481 376.194 477.823 1.00 183.61 ? 62  ARG L CA  1 
ATOM 1419 C C   . ARG B 2 62  ? 350.169 374.859 477.576 1.00 183.61 ? 62  ARG L C   1 
ATOM 1420 O O   . ARG B 2 62  ? 351.353 374.832 477.228 1.00 183.61 ? 62  ARG L O   1 
ATOM 1421 C CB  . ARG B 2 62  ? 349.680 376.612 479.277 1.00 183.61 ? 62  ARG L CB  1 
ATOM 1422 C CG  . ARG B 2 62  ? 349.231 378.021 479.586 1.00 183.61 ? 62  ARG L CG  1 
ATOM 1423 C CD  . ARG B 2 62  ? 349.359 378.287 481.064 1.00 183.61 ? 62  ARG L CD  1 
ATOM 1424 N NE  . ARG B 2 62  ? 348.785 377.193 481.836 1.00 183.61 ? 62  ARG L NE  1 
ATOM 1425 C CZ  . ARG B 2 62  ? 347.514 377.147 482.218 1.00 183.61 ? 62  ARG L CZ  1 
ATOM 1426 N NH1 . ARG B 2 62  ? 346.695 378.140 481.904 1.00 183.61 ? 62  ARG L NH1 1 
ATOM 1427 N NH2 . ARG B 2 62  ? 347.063 376.117 482.920 1.00 183.61 ? 62  ARG L NH2 1 
ATOM 1428 N N   . PHE B 2 63  ? 349.452 373.755 477.737 1.00 185.89 ? 63  PHE L N   1 
ATOM 1429 C CA  . PHE B 2 63  ? 350.065 372.438 477.680 1.00 185.89 ? 63  PHE L CA  1 
ATOM 1430 C C   . PHE B 2 63  ? 350.243 371.990 476.237 1.00 185.89 ? 63  PHE L C   1 
ATOM 1431 O O   . PHE B 2 63  ? 349.343 372.145 475.409 1.00 185.89 ? 63  PHE L O   1 
ATOM 1432 C CB  . PHE B 2 63  ? 349.206 371.426 478.432 1.00 185.89 ? 63  PHE L CB  1 
ATOM 1433 C CG  . PHE B 2 63  ? 348.601 371.969 479.685 1.00 185.89 ? 63  PHE L CG  1 
ATOM 1434 C CD1 . PHE B 2 63  ? 349.358 372.090 480.834 1.00 185.89 ? 63  PHE L CD1 1 
ATOM 1435 C CD2 . PHE B 2 63  ? 347.275 372.366 479.715 1.00 185.89 ? 63  PHE L CD2 1 
ATOM 1436 C CE1 . PHE B 2 63  ? 348.806 372.594 481.996 1.00 185.89 ? 63  PHE L CE1 1 
ATOM 1437 C CE2 . PHE B 2 63  ? 346.717 372.870 480.872 1.00 185.89 ? 63  PHE L CE2 1 
ATOM 1438 C CZ  . PHE B 2 63  ? 347.484 372.983 482.014 1.00 185.89 ? 63  PHE L CZ  1 
ATOM 1439 N N   . SER B 2 64  ? 351.415 371.437 475.937 1.00 182.80 ? 64  SER L N   1 
ATOM 1440 C CA  . SER B 2 64  ? 351.692 370.885 474.612 1.00 182.80 ? 64  SER L CA  1 
ATOM 1441 C C   . SER B 2 64  ? 352.753 369.813 474.767 1.00 182.80 ? 64  SER L C   1 
ATOM 1442 O O   . SER B 2 64  ? 353.696 369.988 475.543 1.00 182.80 ? 64  SER L O   1 
ATOM 1443 C CB  . SER B 2 64  ? 352.166 371.959 473.629 1.00 182.80 ? 64  SER L CB  1 
ATOM 1444 O OG  . SER B 2 64  ? 351.341 373.111 473.633 1.00 182.80 ? 64  SER L OG  1 
ATOM 1445 N N   . GLY B 2 65  ? 352.602 368.712 474.038 1.00 180.14 ? 65  GLY L N   1 
ATOM 1446 C CA  . GLY B 2 65  ? 353.556 367.629 474.079 1.00 180.14 ? 65  GLY L CA  1 
ATOM 1447 C C   . GLY B 2 65  ? 354.157 367.321 472.721 1.00 180.14 ? 65  GLY L C   1 
ATOM 1448 O O   . GLY B 2 65  ? 353.623 367.700 471.682 1.00 180.14 ? 65  GLY L O   1 
ATOM 1449 N N   . SER B 2 66  ? 355.282 366.615 472.741 1.00 177.26 ? 66  SER L N   1 
ATOM 1450 C CA  . SER B 2 66  ? 355.975 366.253 471.512 1.00 177.26 ? 66  SER L CA  1 
ATOM 1451 C C   . SER B 2 66  ? 356.790 364.988 471.760 1.00 177.26 ? 66  SER L C   1 
ATOM 1452 O O   . SER B 2 66  ? 356.729 364.387 472.838 1.00 177.26 ? 66  SER L O   1 
ATOM 1453 C CB  . SER B 2 66  ? 356.859 367.401 471.019 1.00 177.26 ? 66  SER L CB  1 
ATOM 1454 O OG  . SER B 2 66  ? 357.769 366.944 470.035 1.00 177.26 ? 66  SER L OG  1 
ATOM 1455 N N   . GLY B 2 67  ? 357.565 364.594 470.757 1.00 180.13 ? 67  GLY L N   1 
ATOM 1456 C CA  . GLY B 2 67  ? 358.345 363.377 470.794 1.00 180.13 ? 67  GLY L CA  1 
ATOM 1457 C C   . GLY B 2 67  ? 357.891 362.377 469.744 1.00 180.13 ? 67  GLY L C   1 
ATOM 1458 O O   . GLY B 2 67  ? 356.765 362.416 469.243 1.00 180.13 ? 67  GLY L O   1 
ATOM 1459 N N   . SER B 2 68  ? 358.796 361.465 469.403 1.00 176.76 ? 68  SER L N   1 
ATOM 1460 C CA  . SER B 2 68  ? 358.502 360.412 468.441 1.00 176.76 ? 68  SER L CA  1 
ATOM 1461 C C   . SER B 2 68  ? 359.395 359.219 468.750 1.00 176.76 ? 68  SER L C   1 
ATOM 1462 O O   . SER B 2 68  ? 360.319 359.304 469.562 1.00 176.76 ? 68  SER L O   1 
ATOM 1463 C CB  . SER B 2 68  ? 358.695 360.894 467.001 1.00 176.76 ? 68  SER L CB  1 
ATOM 1464 O OG  . SER B 2 68  ? 358.205 359.931 466.085 1.00 176.76 ? 68  SER L OG  1 
ATOM 1465 N N   . GLY B 2 69  ? 359.111 358.103 468.087 1.00 171.88 ? 69  GLY L N   1 
ATOM 1466 C CA  . GLY B 2 69  ? 359.862 356.888 468.313 1.00 171.88 ? 69  GLY L CA  1 
ATOM 1467 C C   . GLY B 2 69  ? 359.569 356.254 469.656 1.00 171.88 ? 69  GLY L C   1 
ATOM 1468 O O   . GLY B 2 69  ? 358.462 355.759 469.892 1.00 171.88 ? 69  GLY L O   1 
ATOM 1469 N N   . THR B 2 70  ? 360.553 356.275 470.553 1.00 173.61 ? 70  THR L N   1 
ATOM 1470 C CA  . THR B 2 70  ? 360.432 355.617 471.842 1.00 173.61 ? 70  THR L CA  1 
ATOM 1471 C C   . THR B 2 70  ? 360.423 356.578 473.022 1.00 173.61 ? 70  THR L C   1 
ATOM 1472 O O   . THR B 2 70  ? 360.236 356.130 474.158 1.00 173.61 ? 70  THR L O   1 
ATOM 1473 C CB  . THR B 2 70  ? 361.566 354.604 472.026 1.00 173.61 ? 70  THR L CB  1 
ATOM 1474 O OG1 . THR B 2 70  ? 361.305 353.801 473.184 1.00 173.61 ? 70  THR L OG1 1 
ATOM 1475 C CG2 . THR B 2 70  ? 362.893 355.323 472.196 1.00 173.61 ? 70  THR L CG2 1 
ATOM 1476 N N   . SER B 2 71  ? 360.607 357.877 472.794 1.00 176.16 ? 71  SER L N   1 
ATOM 1477 C CA  . SER B 2 71  ? 360.636 358.866 473.866 1.00 176.16 ? 71  SER L CA  1 
ATOM 1478 C C   . SER B 2 71  ? 359.679 359.993 473.518 1.00 176.16 ? 71  SER L C   1 
ATOM 1479 O O   . SER B 2 71  ? 359.741 360.543 472.414 1.00 176.16 ? 71  SER L O   1 
ATOM 1480 C CB  . SER B 2 71  ? 362.045 359.419 474.072 1.00 176.16 ? 71  SER L CB  1 
ATOM 1481 O OG  . SER B 2 71  ? 362.261 360.543 473.239 1.00 176.16 ? 71  SER L OG  1 
ATOM 1482 N N   . TYR B 2 72  ? 358.799 360.332 474.454 1.00 178.55 ? 72  TYR L N   1 
ATOM 1483 C CA  . TYR B 2 72  ? 357.802 361.371 474.256 1.00 178.55 ? 72  TYR L CA  1 
ATOM 1484 C C   . TYR B 2 72  ? 357.798 362.295 475.465 1.00 178.55 ? 72  TYR L C   1 
ATOM 1485 O O   . TYR B 2 72  ? 357.973 361.856 476.604 1.00 178.55 ? 72  TYR L O   1 
ATOM 1486 C CB  . TYR B 2 72  ? 356.403 360.771 474.036 1.00 178.55 ? 72  TYR L CB  1 
ATOM 1487 C CG  . TYR B 2 72  ? 356.266 359.919 472.786 1.00 178.55 ? 72  TYR L CG  1 
ATOM 1488 C CD1 . TYR B 2 72  ? 356.668 358.586 472.775 1.00 178.55 ? 72  TYR L CD1 1 
ATOM 1489 C CD2 . TYR B 2 72  ? 355.724 360.444 471.624 1.00 178.55 ? 72  TYR L CD2 1 
ATOM 1490 C CE1 . TYR B 2 72  ? 356.548 357.811 471.643 1.00 178.55 ? 72  TYR L CE1 1 
ATOM 1491 C CE2 . TYR B 2 72  ? 355.592 359.671 470.486 1.00 178.55 ? 72  TYR L CE2 1 
ATOM 1492 C CZ  . TYR B 2 72  ? 356.008 358.357 470.503 1.00 178.55 ? 72  TYR L CZ  1 
ATOM 1493 O OH  . TYR B 2 72  ? 355.883 357.583 469.373 1.00 178.55 ? 72  TYR L OH  1 
ATOM 1494 N N   . SER B 2 73  ? 357.592 363.585 475.209 1.00 184.57 ? 73  SER L N   1 
ATOM 1495 C CA  . SER B 2 73  ? 357.720 364.588 476.255 1.00 184.57 ? 73  SER L CA  1 
ATOM 1496 C C   . SER B 2 73  ? 356.500 365.494 476.257 1.00 184.57 ? 73  SER L C   1 
ATOM 1497 O O   . SER B 2 73  ? 355.702 365.485 475.318 1.00 184.57 ? 73  SER L O   1 
ATOM 1498 C CB  . SER B 2 73  ? 358.985 365.431 476.078 1.00 184.57 ? 73  SER L CB  1 
ATOM 1499 O OG  . SER B 2 73  ? 358.855 366.670 476.752 1.00 184.57 ? 73  SER L OG  1 
ATOM 1500 N N   . LEU B 2 74  ? 356.365 366.273 477.329 1.00 186.22 ? 74  LEU L N   1 
ATOM 1501 C CA  . LEU B 2 74  ? 355.255 367.203 477.502 1.00 186.22 ? 74  LEU L CA  1 
ATOM 1502 C C   . LEU B 2 74  ? 355.809 368.499 478.075 1.00 186.22 ? 74  LEU L C   1 
ATOM 1503 O O   . LEU B 2 74  ? 356.659 368.465 478.969 1.00 186.22 ? 74  LEU L O   1 
ATOM 1504 C CB  . LEU B 2 74  ? 354.187 366.605 478.419 1.00 186.22 ? 74  LEU L CB  1 
ATOM 1505 C CG  . LEU B 2 74  ? 352.773 367.191 478.439 1.00 186.22 ? 74  LEU L CG  1 
ATOM 1506 C CD1 . LEU B 2 74  ? 351.827 366.093 478.826 1.00 186.22 ? 74  LEU L CD1 1 
ATOM 1507 C CD2 . LEU B 2 74  ? 352.604 368.356 479.393 1.00 186.22 ? 74  LEU L CD2 1 
ATOM 1508 N N   . THR B 2 75  ? 355.322 369.633 477.574 1.00 190.38 ? 75  THR L N   1 
ATOM 1509 C CA  . THR B 2 75  ? 355.830 370.946 477.953 1.00 190.38 ? 75  THR L CA  1 
ATOM 1510 C C   . THR B 2 75  ? 354.694 371.863 478.391 1.00 190.38 ? 75  THR L C   1 
ATOM 1511 O O   . THR B 2 75  ? 353.721 372.058 477.655 1.00 190.38 ? 75  THR L O   1 
ATOM 1512 C CB  . THR B 2 75  ? 356.594 371.582 476.786 1.00 190.38 ? 75  THR L CB  1 
ATOM 1513 O OG1 . THR B 2 75  ? 357.755 370.793 476.492 1.00 190.38 ? 75  THR L OG1 1 
ATOM 1514 C CG2 . THR B 2 75  ? 357.022 373.004 477.124 1.00 190.38 ? 75  THR L CG2 1 
ATOM 1515 N N   . ILE B 2 76  ? 354.829 372.433 479.590 1.00 194.29 ? 76  ILE L N   1 
ATOM 1516 C CA  . ILE B 2 76  ? 353.890 373.416 480.123 1.00 194.29 ? 76  ILE L CA  1 
ATOM 1517 C C   . ILE B 2 76  ? 354.574 374.774 480.082 1.00 194.29 ? 76  ILE L C   1 
ATOM 1518 O O   . ILE B 2 76  ? 355.755 374.888 480.431 1.00 194.29 ? 76  ILE L O   1 
ATOM 1519 C CB  . ILE B 2 76  ? 353.449 373.067 481.559 1.00 194.29 ? 76  ILE L CB  1 
ATOM 1520 C CG1 . ILE B 2 76  ? 352.822 371.678 481.645 1.00 194.29 ? 76  ILE L CG1 1 
ATOM 1521 C CG2 . ILE B 2 76  ? 352.424 374.059 482.084 1.00 194.29 ? 76  ILE L CG2 1 
ATOM 1522 C CD1 . ILE B 2 76  ? 353.761 370.598 482.109 1.00 194.29 ? 76  ILE L CD1 1 
ATOM 1523 N N   . SER B 2 77  ? 353.839 375.801 479.649 1.00 196.59 ? 77  SER L N   1 
ATOM 1524 C CA  . SER B 2 77  ? 354.415 377.137 479.541 1.00 196.59 ? 77  SER L CA  1 
ATOM 1525 C C   . SER B 2 77  ? 354.691 377.738 480.915 1.00 196.59 ? 77  SER L C   1 
ATOM 1526 O O   . SER B 2 77  ? 355.829 378.099 481.230 1.00 196.59 ? 77  SER L O   1 
ATOM 1527 C CB  . SER B 2 77  ? 353.481 378.046 478.748 1.00 196.59 ? 77  SER L CB  1 
ATOM 1528 O OG  . SER B 2 77  ? 352.473 378.570 479.594 1.00 196.59 ? 77  SER L OG  1 
ATOM 1529 N N   . SER B 2 78  ? 353.662 377.867 481.743 1.00 198.42 ? 78  SER L N   1 
ATOM 1530 C CA  . SER B 2 78  ? 353.803 378.503 483.044 1.00 198.42 ? 78  SER L CA  1 
ATOM 1531 C C   . SER B 2 78  ? 353.095 377.671 484.100 1.00 198.42 ? 78  SER L C   1 
ATOM 1532 O O   . SER B 2 78  ? 352.006 377.142 483.856 1.00 198.42 ? 78  SER L O   1 
ATOM 1533 C CB  . SER B 2 78  ? 353.240 379.926 483.027 1.00 198.42 ? 78  SER L CB  1 
ATOM 1534 O OG  . SER B 2 78  ? 353.722 380.672 484.129 1.00 198.42 ? 78  SER L OG  1 
ATOM 1535 N N   . VAL B 2 79  ? 353.712 377.564 485.264 1.00 199.61 ? 79  VAL L N   1 
ATOM 1536 C CA  . VAL B 2 79  ? 353.121 376.874 486.400 1.00 199.61 ? 79  VAL L CA  1 
ATOM 1537 C C   . VAL B 2 79  ? 352.042 377.771 486.990 1.00 199.61 ? 79  VAL L C   1 
ATOM 1538 O O   . VAL B 2 79  ? 352.270 378.964 487.216 1.00 199.61 ? 79  VAL L O   1 
ATOM 1539 C CB  . VAL B 2 79  ? 354.197 376.527 487.444 1.00 199.61 ? 79  VAL L CB  1 
ATOM 1540 C CG1 . VAL B 2 79  ? 353.577 375.975 488.723 1.00 199.61 ? 79  VAL L CG1 1 
ATOM 1541 C CG2 . VAL B 2 79  ? 355.190 375.545 486.857 1.00 199.61 ? 79  VAL L CG2 1 
ATOM 1542 N N   . GLU B 2 80  ? 350.868 377.203 487.227 1.00 193.22 ? 80  GLU L N   1 
ATOM 1543 C CA  . GLU B 2 80  ? 349.741 377.913 487.812 1.00 193.22 ? 80  GLU L CA  1 
ATOM 1544 C C   . GLU B 2 80  ? 349.409 377.293 489.167 1.00 193.22 ? 80  GLU L C   1 
ATOM 1545 O O   . GLU B 2 80  ? 350.149 376.460 489.689 1.00 193.22 ? 80  GLU L O   1 
ATOM 1546 C CB  . GLU B 2 80  ? 348.546 377.897 486.860 1.00 193.22 ? 80  GLU L CB  1 
ATOM 1547 C CG  . GLU B 2 80  ? 348.682 378.865 485.700 1.00 193.22 ? 80  GLU L CG  1 
ATOM 1548 C CD  . GLU B 2 80  ? 347.378 379.072 484.964 1.00 193.22 ? 80  GLU L CD  1 
ATOM 1549 O OE1 . GLU B 2 80  ? 347.225 380.119 484.300 1.00 193.22 ? 80  GLU L OE1 1 
ATOM 1550 O OE2 . GLU B 2 80  ? 346.507 378.183 485.047 1.00 193.22 ? 80  GLU L OE2 1 
ATOM 1551 N N   . ALA B 2 81  ? 348.285 377.710 489.741 1.00 197.39 ? 81  ALA L N   1 
ATOM 1552 C CA  . ALA B 2 81  ? 347.948 377.332 491.105 1.00 197.39 ? 81  ALA L CA  1 
ATOM 1553 C C   . ALA B 2 81  ? 347.185 376.019 491.214 1.00 197.39 ? 81  ALA L C   1 
ATOM 1554 O O   . ALA B 2 81  ? 347.144 375.439 492.304 1.00 197.39 ? 81  ALA L O   1 
ATOM 1555 C CB  . ALA B 2 81  ? 347.128 378.442 491.768 1.00 197.39 ? 81  ALA L CB  1 
ATOM 1556 N N   . GLU B 2 82  ? 346.583 375.532 490.132 1.00 194.08 ? 82  GLU L N   1 
ATOM 1557 C CA  . GLU B 2 82  ? 345.681 374.391 490.220 1.00 194.08 ? 82  GLU L CA  1 
ATOM 1558 C C   . GLU B 2 82  ? 346.237 373.111 489.611 1.00 194.08 ? 82  GLU L C   1 
ATOM 1559 O O   . GLU B 2 82  ? 345.546 372.088 489.638 1.00 194.08 ? 82  GLU L O   1 
ATOM 1560 C CB  . GLU B 2 82  ? 344.343 374.723 489.547 1.00 194.08 ? 82  GLU L CB  1 
ATOM 1561 C CG  . GLU B 2 82  ? 344.449 375.068 488.067 1.00 194.08 ? 82  GLU L CG  1 
ATOM 1562 C CD  . GLU B 2 82  ? 344.578 376.559 487.814 1.00 194.08 ? 82  GLU L CD  1 
ATOM 1563 O OE1 . GLU B 2 82  ? 343.954 377.053 486.852 1.00 194.08 ? 82  GLU L OE1 1 
ATOM 1564 O OE2 . GLU B 2 82  ? 345.300 377.239 488.574 1.00 194.08 ? 82  GLU L OE2 1 
ATOM 1565 N N   . ASP B 2 83  ? 347.452 373.132 489.067 1.00 197.12 ? 83  ASP L N   1 
ATOM 1566 C CA  . ASP B 2 83  ? 347.994 371.993 488.328 1.00 197.12 ? 83  ASP L CA  1 
ATOM 1567 C C   . ASP B 2 83  ? 349.137 371.306 489.062 1.00 197.12 ? 83  ASP L C   1 
ATOM 1568 O O   . ASP B 2 83  ? 350.143 370.936 488.452 1.00 197.12 ? 83  ASP L O   1 
ATOM 1569 C CB  . ASP B 2 83  ? 348.440 372.428 486.939 1.00 197.12 ? 83  ASP L CB  1 
ATOM 1570 C CG  . ASP B 2 83  ? 349.304 373.650 486.978 1.00 197.12 ? 83  ASP L CG  1 
ATOM 1571 O OD1 . ASP B 2 83  ? 349.059 374.505 487.848 1.00 197.12 ? 83  ASP L OD1 1 
ATOM 1572 O OD2 . ASP B 2 83  ? 350.224 373.756 486.144 1.00 197.12 ? 83  ASP L OD2 1 
ATOM 1573 N N   . ALA B 2 84  ? 349.025 371.142 490.374 1.00 200.85 ? 84  ALA L N   1 
ATOM 1574 C CA  . ALA B 2 84  ? 349.971 370.339 491.145 1.00 200.85 ? 84  ALA L CA  1 
ATOM 1575 C C   . ALA B 2 84  ? 349.291 369.011 491.459 1.00 200.85 ? 84  ALA L C   1 
ATOM 1576 O O   . ALA B 2 84  ? 348.525 368.907 492.420 1.00 200.85 ? 84  ALA L O   1 
ATOM 1577 C CB  . ALA B 2 84  ? 350.403 371.068 492.412 1.00 200.85 ? 84  ALA L CB  1 
ATOM 1578 N N   . ALA B 2 85  ? 349.572 367.998 490.647 1.00 192.83 ? 85  ALA L N   1 
ATOM 1579 C CA  . ALA B 2 85  ? 348.910 366.704 490.758 1.00 192.83 ? 85  ALA L CA  1 
ATOM 1580 C C   . ALA B 2 85  ? 349.793 365.647 490.106 1.00 192.83 ? 85  ALA L C   1 
ATOM 1581 O O   . ALA B 2 85  ? 350.984 365.871 489.863 1.00 192.83 ? 85  ALA L O   1 
ATOM 1582 C CB  . ALA B 2 85  ? 347.515 366.743 490.129 1.00 192.83 ? 85  ALA L CB  1 
ATOM 1583 N N   . THR B 2 86  ? 349.205 364.486 489.834 1.00 186.75 ? 86  THR L N   1 
ATOM 1584 C CA  . THR B 2 86  ? 349.905 363.345 489.260 1.00 186.75 ? 86  THR L CA  1 
ATOM 1585 C C   . THR B 2 86  ? 349.711 363.316 487.751 1.00 186.75 ? 86  THR L C   1 
ATOM 1586 O O   . THR B 2 86  ? 348.789 363.946 487.225 1.00 186.75 ? 86  THR L O   1 
ATOM 1587 C CB  . THR B 2 86  ? 349.403 362.038 489.873 1.00 186.75 ? 86  THR L CB  1 
ATOM 1588 O OG1 . THR B 2 86  ? 347.974 362.079 489.982 1.00 186.75 ? 86  THR L OG1 1 
ATOM 1589 C CG2 . THR B 2 86  ? 350.008 361.835 491.250 1.00 186.75 ? 86  THR L CG2 1 
ATOM 1590 N N   . TYR B 2 87  ? 350.589 362.594 487.062 1.00 187.61 ? 87  TYR L N   1 
ATOM 1591 C CA  . TYR B 2 87  ? 350.542 362.436 485.615 1.00 187.61 ? 87  TYR L CA  1 
ATOM 1592 C C   . TYR B 2 87  ? 350.843 360.987 485.261 1.00 187.61 ? 87  TYR L C   1 
ATOM 1593 O O   . TYR B 2 87  ? 351.654 360.338 485.929 1.00 187.61 ? 87  TYR L O   1 
ATOM 1594 C CB  . TYR B 2 87  ? 351.551 363.354 484.924 1.00 187.61 ? 87  TYR L CB  1 
ATOM 1595 C CG  . TYR B 2 87  ? 351.099 364.781 484.734 1.00 187.61 ? 87  TYR L CG  1 
ATOM 1596 C CD1 . TYR B 2 87  ? 351.133 365.688 485.784 1.00 187.61 ? 87  TYR L CD1 1 
ATOM 1597 C CD2 . TYR B 2 87  ? 350.667 365.228 483.494 1.00 187.61 ? 87  TYR L CD2 1 
ATOM 1598 C CE1 . TYR B 2 87  ? 350.728 366.996 485.609 1.00 187.61 ? 87  TYR L CE1 1 
ATOM 1599 C CE2 . TYR B 2 87  ? 350.263 366.534 483.308 1.00 187.61 ? 87  TYR L CE2 1 
ATOM 1600 C CZ  . TYR B 2 87  ? 350.296 367.412 484.368 1.00 187.61 ? 87  TYR L CZ  1 
ATOM 1601 O OH  . TYR B 2 87  ? 349.893 368.713 484.187 1.00 187.61 ? 87  TYR L OH  1 
ATOM 1602 N N   . TYR B 2 88  ? 350.195 360.485 484.213 1.00 184.51 ? 88  TYR L N   1 
ATOM 1603 C CA  . TYR B 2 88  ? 350.455 359.156 483.682 1.00 184.51 ? 88  TYR L CA  1 
ATOM 1604 C C   . TYR B 2 88  ? 350.416 359.177 482.159 1.00 184.51 ? 88  TYR L C   1 
ATOM 1605 O O   . TYR B 2 88  ? 349.626 359.904 481.552 1.00 184.51 ? 88  TYR L O   1 
ATOM 1606 C CB  . TYR B 2 88  ? 349.434 358.139 484.199 1.00 184.51 ? 88  TYR L CB  1 
ATOM 1607 C CG  . TYR B 2 88  ? 349.414 357.993 485.699 1.00 184.51 ? 88  TYR L CG  1 
ATOM 1608 C CD1 . TYR B 2 88  ? 350.447 357.349 486.366 1.00 184.51 ? 88  TYR L CD1 1 
ATOM 1609 C CD2 . TYR B 2 88  ? 348.362 358.494 486.448 1.00 184.51 ? 88  TYR L CD2 1 
ATOM 1610 C CE1 . TYR B 2 88  ? 350.433 357.212 487.740 1.00 184.51 ? 88  TYR L CE1 1 
ATOM 1611 C CE2 . TYR B 2 88  ? 348.338 358.362 487.822 1.00 184.51 ? 88  TYR L CE2 1 
ATOM 1612 C CZ  . TYR B 2 88  ? 349.375 357.721 488.461 1.00 184.51 ? 88  TYR L CZ  1 
ATOM 1613 O OH  . TYR B 2 88  ? 349.354 357.588 489.828 1.00 184.51 ? 88  TYR L OH  1 
ATOM 1614 N N   . CYS B 2 89  ? 351.272 358.368 481.543 1.00 182.91 ? 89  CYS L N   1 
ATOM 1615 C CA  . CYS B 2 89  ? 351.245 358.163 480.104 1.00 182.91 ? 89  CYS L CA  1 
ATOM 1616 C C   . CYS B 2 89  ? 350.845 356.724 479.810 1.00 182.91 ? 89  CYS L C   1 
ATOM 1617 O O   . CYS B 2 89  ? 351.193 355.807 480.559 1.00 182.91 ? 89  CYS L O   1 
ATOM 1618 C CB  . CYS B 2 89  ? 352.598 358.493 479.451 1.00 182.91 ? 89  CYS L CB  1 
ATOM 1619 S SG  . CYS B 2 89  ? 354.037 357.591 480.065 1.00 182.91 ? 89  CYS L SG  1 
ATOM 1620 N N   . GLN B 2 90  ? 350.099 356.541 478.727 1.00 171.38 ? 90  GLN L N   1 
ATOM 1621 C CA  . GLN B 2 90  ? 349.540 355.259 478.331 1.00 171.38 ? 90  GLN L CA  1 
ATOM 1622 C C   . GLN B 2 90  ? 350.035 354.914 476.932 1.00 171.38 ? 90  GLN L C   1 
ATOM 1623 O O   . GLN B 2 90  ? 350.292 355.797 476.116 1.00 171.38 ? 90  GLN L O   1 
ATOM 1624 C CB  . GLN B 2 90  ? 348.004 355.315 478.378 1.00 171.38 ? 90  GLN L CB  1 
ATOM 1625 C CG  . GLN B 2 90  ? 347.281 353.986 478.280 1.00 171.38 ? 90  GLN L CG  1 
ATOM 1626 C CD  . GLN B 2 90  ? 346.940 353.618 476.852 1.00 171.38 ? 90  GLN L CD  1 
ATOM 1627 O OE1 . GLN B 2 90  ? 347.080 354.433 475.943 1.00 171.38 ? 90  GLN L OE1 1 
ATOM 1628 N NE2 . GLN B 2 90  ? 346.483 352.391 476.648 1.00 171.38 ? 90  GLN L NE2 1 
ATOM 1629 N N   . GLN B 2 91  ? 350.179 353.619 476.656 1.00 166.05 ? 91  GLN L N   1 
ATOM 1630 C CA  . GLN B 2 91  ? 350.707 353.167 475.377 1.00 166.05 ? 91  GLN L CA  1 
ATOM 1631 C C   . GLN B 2 91  ? 349.860 352.024 474.838 1.00 166.05 ? 91  GLN L C   1 
ATOM 1632 O O   . GLN B 2 91  ? 349.100 351.385 475.569 1.00 166.05 ? 91  GLN L O   1 
ATOM 1633 C CB  . GLN B 2 91  ? 352.166 352.717 475.503 1.00 166.05 ? 91  GLN L CB  1 
ATOM 1634 C CG  . GLN B 2 91  ? 352.352 351.528 476.425 1.00 166.05 ? 91  GLN L CG  1 
ATOM 1635 C CD  . GLN B 2 91  ? 352.516 350.220 475.683 1.00 166.05 ? 91  GLN L CD  1 
ATOM 1636 O OE1 . GLN B 2 91  ? 352.781 350.202 474.483 1.00 166.05 ? 91  GLN L OE1 1 
ATOM 1637 N NE2 . GLN B 2 91  ? 352.357 349.113 476.397 1.00 166.05 ? 91  GLN L NE2 1 
ATOM 1638 N N   . PHE B 2 92  ? 350.010 351.768 473.538 1.00 151.33 ? 92  PHE L N   1 
ATOM 1639 C CA  . PHE B 2 92  ? 349.464 350.560 472.924 1.00 151.33 ? 92  PHE L CA  1 
ATOM 1640 C C   . PHE B 2 92  ? 350.285 350.229 471.687 1.00 151.33 ? 92  PHE L C   1 
ATOM 1641 O O   . PHE B 2 92  ? 350.092 350.844 470.636 1.00 151.33 ? 92  PHE L O   1 
ATOM 1642 C CB  . PHE B 2 92  ? 347.999 350.729 472.556 1.00 151.33 ? 92  PHE L CB  1 
ATOM 1643 C CG  . PHE B 2 92  ? 347.460 349.607 471.711 1.00 151.33 ? 92  PHE L CG  1 
ATOM 1644 C CD1 . PHE B 2 92  ? 347.548 348.290 472.137 1.00 151.33 ? 92  PHE L CD1 1 
ATOM 1645 C CD2 . PHE B 2 92  ? 346.880 349.866 470.485 1.00 151.33 ? 92  PHE L CD2 1 
ATOM 1646 C CE1 . PHE B 2 92  ? 347.057 347.262 471.358 1.00 151.33 ? 92  PHE L CE1 1 
ATOM 1647 C CE2 . PHE B 2 92  ? 346.394 348.835 469.704 1.00 151.33 ? 92  PHE L CE2 1 
ATOM 1648 C CZ  . PHE B 2 92  ? 346.482 347.536 470.143 1.00 151.33 ? 92  PHE L CZ  1 
ATOM 1649 N N   . SER B 2 93  ? 351.185 349.264 471.809 0.00 148.58 ? 93  SER L N   1 
ATOM 1650 C CA  . SER B 2 93  ? 351.708 348.557 470.650 0.00 148.58 ? 93  SER L CA  1 
ATOM 1651 C C   . SER B 2 93  ? 351.077 347.189 470.504 0.00 148.58 ? 93  SER L C   1 
ATOM 1652 O O   . SER B 2 93  ? 350.863 346.721 469.387 0.00 148.58 ? 93  SER L O   1 
ATOM 1653 C CB  . SER B 2 93  ? 353.229 348.405 470.743 0.00 148.58 ? 93  SER L CB  1 
ATOM 1654 O OG  . SER B 2 93  ? 353.707 347.523 469.743 0.00 148.58 ? 93  SER L OG  1 
ATOM 1655 N N   . GLY B 2 94  ? 350.776 346.553 471.631 1.00 141.08 ? 94  GLY L N   1 
ATOM 1656 C CA  . GLY B 2 94  ? 350.024 345.320 471.664 1.00 141.08 ? 94  GLY L CA  1 
ATOM 1657 C C   . GLY B 2 94  ? 349.314 345.252 472.996 1.00 141.08 ? 94  GLY L C   1 
ATOM 1658 O O   . GLY B 2 94  ? 349.441 346.144 473.836 1.00 141.08 ? 94  GLY L O   1 
ATOM 1659 N N   . TYR B 2 95  ? 348.551 344.190 473.175 1.00 139.84 ? 95  TYR L N   1 
ATOM 1660 C CA  . TYR B 2 95  ? 347.935 343.956 474.466 1.00 139.84 ? 95  TYR L CA  1 
ATOM 1661 C C   . TYR B 2 95  ? 348.961 343.347 475.416 1.00 139.84 ? 95  TYR L C   1 
ATOM 1662 O O   . TYR B 2 95  ? 349.734 342.474 475.014 1.00 139.84 ? 95  TYR L O   1 
ATOM 1663 C CB  . TYR B 2 95  ? 346.729 343.036 474.317 1.00 139.84 ? 95  TYR L CB  1 
ATOM 1664 C CG  . TYR B 2 95  ? 345.663 343.602 473.408 1.00 139.84 ? 95  TYR L CG  1 
ATOM 1665 C CD1 . TYR B 2 95  ? 344.727 344.510 473.884 1.00 139.84 ? 95  TYR L CD1 1 
ATOM 1666 C CD2 . TYR B 2 95  ? 345.597 343.231 472.074 1.00 139.84 ? 95  TYR L CD2 1 
ATOM 1667 C CE1 . TYR B 2 95  ? 343.758 345.026 473.059 1.00 139.84 ? 95  TYR L CE1 1 
ATOM 1668 C CE2 . TYR B 2 95  ? 344.630 343.742 471.244 1.00 139.84 ? 95  TYR L CE2 1 
ATOM 1669 C CZ  . TYR B 2 95  ? 343.717 344.637 471.742 1.00 139.84 ? 95  TYR L CZ  1 
ATOM 1670 O OH  . TYR B 2 95  ? 342.755 345.142 470.908 1.00 139.84 ? 95  TYR L OH  1 
ATOM 1671 N N   . PRO B 2 96  ? 348.991 343.772 476.687 1.00 148.75 ? 96  PRO L N   1 
ATOM 1672 C CA  . PRO B 2 96  ? 348.054 344.663 477.378 1.00 148.75 ? 96  PRO L CA  1 
ATOM 1673 C C   . PRO B 2 96  ? 348.335 346.151 477.204 1.00 148.75 ? 96  PRO L C   1 
ATOM 1674 O O   . PRO B 2 96  ? 349.393 346.524 476.707 1.00 148.75 ? 96  PRO L O   1 
ATOM 1675 C CB  . PRO B 2 96  ? 348.244 344.267 478.838 1.00 148.75 ? 96  PRO L CB  1 
ATOM 1676 C CG  . PRO B 2 96  ? 349.693 343.927 478.920 1.00 148.75 ? 96  PRO L CG  1 
ATOM 1677 C CD  . PRO B 2 96  ? 350.072 343.330 477.585 1.00 148.75 ? 96  PRO L CD  1 
ATOM 1678 N N   . LEU B 2 97  ? 347.380 346.983 477.616 1.00 160.47 ? 97  LEU L N   1 
ATOM 1679 C CA  . LEU B 2 97  ? 347.573 348.427 477.691 1.00 160.47 ? 97  LEU L CA  1 
ATOM 1680 C C   . LEU B 2 97  ? 348.287 348.740 478.998 1.00 160.47 ? 97  LEU L C   1 
ATOM 1681 O O   . LEU B 2 97  ? 347.686 348.665 480.074 1.00 160.47 ? 97  LEU L O   1 
ATOM 1682 C CB  . LEU B 2 97  ? 346.240 349.165 477.623 1.00 160.47 ? 97  LEU L CB  1 
ATOM 1683 C CG  . LEU B 2 97  ? 345.279 348.869 476.478 1.00 160.47 ? 97  LEU L CG  1 
ATOM 1684 C CD1 . LEU B 2 97  ? 343.966 349.593 476.699 1.00 160.47 ? 97  LEU L CD1 1 
ATOM 1685 C CD2 . LEU B 2 97  ? 345.893 349.294 475.186 1.00 160.47 ? 97  LEU L CD2 1 
ATOM 1686 N N   . THR B 2 98  ? 349.560 349.092 478.911 1.00 168.05 ? 98  THR L N   1 
ATOM 1687 C CA  . THR B 2 98  ? 350.377 349.307 480.093 1.00 168.05 ? 98  THR L CA  1 
ATOM 1688 C C   . THR B 2 98  ? 350.513 350.794 480.372 1.00 168.05 ? 98  THR L C   1 
ATOM 1689 O O   . THR B 2 98  ? 350.623 351.602 479.448 1.00 168.05 ? 98  THR L O   1 
ATOM 1690 C CB  . THR B 2 98  ? 351.754 348.678 479.916 1.00 168.05 ? 98  THR L CB  1 
ATOM 1691 O OG1 . THR B 2 98  ? 352.545 349.504 479.054 1.00 168.05 ? 98  THR L OG1 1 
ATOM 1692 C CG2 . THR B 2 98  ? 351.616 347.293 479.302 1.00 168.05 ? 98  THR L CG2 1 
ATOM 1693 N N   . PHE B 2 99  ? 350.503 351.146 481.649 1.00 173.51 ? 99  PHE L N   1 
ATOM 1694 C CA  . PHE B 2 99  ? 350.561 352.537 482.062 1.00 173.51 ? 99  PHE L CA  1 
ATOM 1695 C C   . PHE B 2 99  ? 351.948 352.886 482.583 1.00 173.51 ? 99  PHE L C   1 
ATOM 1696 O O   . PHE B 2 99  ? 352.821 352.028 482.726 1.00 173.51 ? 99  PHE L O   1 
ATOM 1697 C CB  . PHE B 2 99  ? 349.508 352.821 483.129 1.00 173.51 ? 99  PHE L CB  1 
ATOM 1698 C CG  . PHE B 2 99  ? 348.116 352.909 482.588 1.00 173.51 ? 99  PHE L CG  1 
ATOM 1699 C CD1 . PHE B 2 99  ? 347.365 351.767 482.380 1.00 173.51 ? 99  PHE L CD1 1 
ATOM 1700 C CD2 . PHE B 2 99  ? 347.559 354.135 482.281 1.00 173.51 ? 99  PHE L CD2 1 
ATOM 1701 C CE1 . PHE B 2 99  ? 346.082 351.848 481.879 1.00 173.51 ? 99  PHE L CE1 1 
ATOM 1702 C CE2 . PHE B 2 99  ? 346.277 354.221 481.783 1.00 173.51 ? 99  PHE L CE2 1 
ATOM 1703 C CZ  . PHE B 2 99  ? 345.540 353.076 481.581 1.00 173.51 ? 99  PHE L CZ  1 
ATOM 1704 N N   . GLY B 2 100 ? 352.142 354.172 482.863 1.00 182.78 ? 100 GLY L N   1 
ATOM 1705 C CA  . GLY B 2 100 ? 353.431 354.669 483.287 1.00 182.78 ? 100 GLY L CA  1 
ATOM 1706 C C   . GLY B 2 100 ? 353.611 354.636 484.790 1.00 182.78 ? 100 GLY L C   1 
ATOM 1707 O O   . GLY B 2 100 ? 352.714 354.286 485.555 1.00 182.78 ? 100 GLY L O   1 
ATOM 1708 N N   . ALA B 2 101 ? 354.815 355.020 485.215 1.00 187.20 ? 101 ALA L N   1 
ATOM 1709 C CA  . ALA B 2 101 ? 355.148 354.981 486.635 1.00 187.20 ? 101 ALA L CA  1 
ATOM 1710 C C   . ALA B 2 101 ? 354.465 356.112 487.389 1.00 187.20 ? 101 ALA L C   1 
ATOM 1711 O O   . ALA B 2 101 ? 353.818 355.884 488.417 1.00 187.20 ? 101 ALA L O   1 
ATOM 1712 N N   . GLY B 2 102 ? 354.594 357.338 486.895 1.00 192.71 ? 102 GLY L N   1 
ATOM 1713 C CA  . GLY B 2 102 ? 353.939 358.463 487.528 1.00 192.71 ? 102 GLY L CA  1 
ATOM 1714 C C   . GLY B 2 102 ? 354.838 359.663 487.720 1.00 192.71 ? 102 GLY L C   1 
ATOM 1715 O O   . GLY B 2 102 ? 356.022 359.515 488.031 1.00 192.71 ? 102 GLY L O   1 
ATOM 1716 N N   . THR B 2 103 ? 354.285 360.859 487.533 1.00 198.03 ? 103 THR L N   1 
ATOM 1717 C CA  . THR B 2 103 ? 355.003 362.112 487.727 1.00 198.03 ? 103 THR L CA  1 
ATOM 1718 C C   . THR B 2 103 ? 354.232 362.967 488.721 1.00 198.03 ? 103 THR L C   1 
ATOM 1719 O O   . THR B 2 103 ? 353.182 363.524 488.384 1.00 198.03 ? 103 THR L O   1 
ATOM 1720 C CB  . THR B 2 103 ? 355.175 362.855 486.405 1.00 198.03 ? 103 THR L CB  1 
ATOM 1721 O OG1 . THR B 2 103 ? 355.926 362.041 485.496 1.00 198.03 ? 103 THR L OG1 1 
ATOM 1722 C CG2 . THR B 2 103 ? 355.903 364.169 486.628 1.00 198.03 ? 103 THR L CG2 1 
ATOM 1723 N N   . LYS B 2 104 ? 354.749 363.067 489.939 1.00 200.90 ? 104 LYS L N   1 
ATOM 1724 C CA  . LYS B 2 104 ? 354.094 363.805 491.009 1.00 200.90 ? 104 LYS L CA  1 
ATOM 1725 C C   . LYS B 2 104 ? 354.669 365.211 491.083 1.00 200.90 ? 104 LYS L C   1 
ATOM 1726 O O   . LYS B 2 104 ? 355.891 365.387 491.091 1.00 200.90 ? 104 LYS L O   1 
ATOM 1727 C CB  . LYS B 2 104 ? 354.260 363.085 492.347 1.00 200.90 ? 104 LYS L CB  1 
ATOM 1728 C CG  . LYS B 2 104 ? 353.689 361.671 492.356 1.00 200.90 ? 104 LYS L CG  1 
ATOM 1729 C CD  . LYS B 2 104 ? 354.553 360.696 493.152 1.00 200.90 ? 104 LYS L CD  1 
ATOM 1730 C CE  . LYS B 2 104 ? 355.851 360.366 492.433 1.00 200.90 ? 104 LYS L CE  1 
ATOM 1731 N NZ  . LYS B 2 104 ? 356.544 359.191 493.028 1.00 200.90 ? 104 LYS L NZ  1 
ATOM 1732 N N   . LEU B 2 105 ? 353.787 366.204 491.138 1.00 203.00 ? 105 LEU L N   1 
ATOM 1733 C CA  . LEU B 2 105 ? 354.165 367.611 491.066 1.00 203.00 ? 105 LEU L CA  1 
ATOM 1734 C C   . LEU B 2 105 ? 353.577 368.344 492.265 1.00 203.00 ? 105 LEU L C   1 
ATOM 1735 O O   . LEU B 2 105 ? 352.362 368.303 492.489 1.00 203.00 ? 105 LEU L O   1 
ATOM 1736 C CB  . LEU B 2 105 ? 353.680 368.225 489.755 1.00 203.00 ? 105 LEU L CB  1 
ATOM 1737 C CG  . LEU B 2 105 ? 354.421 369.455 489.239 1.00 203.00 ? 105 LEU L CG  1 
ATOM 1738 C CD1 . LEU B 2 105 ? 355.853 369.104 488.867 1.00 203.00 ? 105 LEU L CD1 1 
ATOM 1739 C CD2 . LEU B 2 105 ? 353.682 370.042 488.053 1.00 203.00 ? 105 LEU L CD2 1 
ATOM 1740 N N   . GLU B 2 106 ? 354.434 369.010 493.035 1.00 208.75 ? 106 GLU L N   1 
ATOM 1741 C CA  . GLU B 2 106 ? 354.008 369.827 494.164 1.00 208.75 ? 106 GLU L CA  1 
ATOM 1742 C C   . GLU B 2 106 ? 354.433 371.271 493.927 1.00 208.75 ? 106 GLU L C   1 
ATOM 1743 O O   . GLU B 2 106 ? 355.551 371.524 493.466 1.00 208.75 ? 106 GLU L O   1 
ATOM 1744 C CB  . GLU B 2 106 ? 354.596 369.285 495.472 1.00 208.75 ? 106 GLU L CB  1 
ATOM 1745 C CG  . GLU B 2 106 ? 354.697 370.282 496.634 1.00 208.75 ? 106 GLU L CG  1 
ATOM 1746 C CD  . GLU B 2 106 ? 353.343 370.705 497.189 1.00 208.75 ? 106 GLU L CD  1 
ATOM 1747 O OE1 . GLU B 2 106 ? 352.385 369.909 497.107 1.00 208.75 ? 106 GLU L OE1 1 
ATOM 1748 O OE2 . GLU B 2 106 ? 353.236 371.836 497.709 1.00 208.75 ? 106 GLU L OE2 1 
ATOM 1749 N N   . LEU B 2 107 ? 353.530 372.207 494.215 1.00 209.49 ? 107 LEU L N   1 
ATOM 1750 C CA  . LEU B 2 107 ? 353.807 373.629 494.072 1.00 209.49 ? 107 LEU L CA  1 
ATOM 1751 C C   . LEU B 2 107 ? 354.888 374.089 495.047 1.00 209.49 ? 107 LEU L C   1 
ATOM 1752 O O   . LEU B 2 107 ? 355.133 373.476 496.088 1.00 209.49 ? 107 LEU L O   1 
ATOM 1753 C CB  . LEU B 2 107 ? 352.538 374.444 494.308 1.00 209.49 ? 107 LEU L CB  1 
ATOM 1754 C CG  . LEU B 2 107 ? 351.584 374.616 493.133 1.00 209.49 ? 107 LEU L CG  1 
ATOM 1755 C CD1 . LEU B 2 107 ? 350.157 374.780 493.625 1.00 209.49 ? 107 LEU L CD1 1 
ATOM 1756 C CD2 . LEU B 2 107 ? 352.019 375.825 492.325 1.00 209.49 ? 107 LEU L CD2 1 
ATOM 1757 N N   . LYS B 2 108 ? 355.533 375.195 494.697 1.00 205.93 ? 108 LYS L N   1 
ATOM 1758 C CA  . LYS B 2 108 ? 356.533 375.789 495.569 1.00 205.93 ? 108 LYS L CA  1 
ATOM 1759 C C   . LYS B 2 108 ? 356.164 377.227 495.913 1.00 205.93 ? 108 LYS L C   1 
ATOM 1760 O O   . LYS B 2 108 ? 355.080 377.494 496.433 1.00 205.93 ? 108 LYS L O   1 
ATOM 1761 C CB  . LYS B 2 108 ? 357.914 375.738 494.918 1.00 205.93 ? 108 LYS L CB  1 
ATOM 1762 C CG  . LYS B 2 108 ? 359.014 376.320 495.781 1.00 205.93 ? 108 LYS L CG  1 
ATOM 1763 C CD  . LYS B 2 108 ? 359.257 375.466 497.011 1.00 205.93 ? 108 LYS L CD  1 
ATOM 1764 C CE  . LYS B 2 108 ? 360.431 375.993 497.816 1.00 205.93 ? 108 LYS L CE  1 
ATOM 1765 N NZ  . LYS B 2 108 ? 360.128 377.327 498.405 1.00 205.93 ? 108 LYS L NZ  1 
ATOM 1766 N N   . SER C 3 58  ? 358.855 345.331 425.082 1.00 131.87 ? 58  SER A N   1 
ATOM 1767 C CA  . SER C 3 58  ? 359.541 344.147 425.581 1.00 131.87 ? 58  SER A CA  1 
ATOM 1768 C C   . SER C 3 58  ? 358.865 343.619 426.837 1.00 131.87 ? 58  SER A C   1 
ATOM 1769 O O   . SER C 3 58  ? 359.409 343.717 427.935 1.00 131.87 ? 58  SER A O   1 
ATOM 1770 C CB  . SER C 3 58  ? 361.011 344.453 425.865 1.00 131.87 ? 58  SER A CB  1 
ATOM 1771 O OG  . SER C 3 58  ? 361.694 344.813 424.678 1.00 131.87 ? 58  SER A OG  1 
ATOM 1772 N N   . ARG C 3 59  ? 357.670 343.053 426.662 1.00 123.59 ? 59  ARG A N   1 
ATOM 1773 C CA  . ARG C 3 59  ? 356.910 342.467 427.760 1.00 123.59 ? 59  ARG A CA  1 
ATOM 1774 C C   . ARG C 3 59  ? 357.220 340.983 427.930 1.00 123.59 ? 59  ARG A C   1 
ATOM 1775 O O   . ARG C 3 59  ? 356.697 340.344 428.848 1.00 123.59 ? 59  ARG A O   1 
ATOM 1776 C CB  . ARG C 3 59  ? 355.409 342.684 427.543 1.00 123.59 ? 59  ARG A CB  1 
ATOM 1777 C CG  . ARG C 3 59  ? 354.901 344.036 428.039 1.00 123.59 ? 59  ARG A CG  1 
ATOM 1778 C CD  . ARG C 3 59  ? 353.399 344.202 427.830 1.00 123.59 ? 59  ARG A CD  1 
ATOM 1779 N NE  . ARG C 3 59  ? 352.818 345.151 428.778 1.00 123.59 ? 59  ARG A NE  1 
ATOM 1780 C CZ  . ARG C 3 59  ? 352.188 346.273 428.443 1.00 123.59 ? 59  ARG A CZ  1 
ATOM 1781 N NH1 . ARG C 3 59  ? 352.046 346.610 427.170 1.00 123.59 ? 59  ARG A NH1 1 
ATOM 1782 N NH2 . ARG C 3 59  ? 351.706 347.061 429.394 1.00 123.59 ? 59  ARG A NH2 1 
ATOM 1783 N N   . SER C 3 60  ? 358.077 340.429 427.067 1.00 116.77 ? 60  SER A N   1 
ATOM 1784 C CA  . SER C 3 60  ? 358.450 339.025 427.116 1.00 116.77 ? 60  SER A CA  1 
ATOM 1785 C C   . SER C 3 60  ? 359.223 338.650 428.365 1.00 116.77 ? 60  SER A C   1 
ATOM 1786 O O   . SER C 3 60  ? 359.263 337.467 428.713 1.00 116.77 ? 60  SER A O   1 
ATOM 1787 C CB  . SER C 3 60  ? 359.287 338.651 425.885 1.00 116.77 ? 60  SER A CB  1 
ATOM 1788 O OG  . SER C 3 60  ? 359.712 337.303 425.954 1.00 116.77 ? 60  SER A OG  1 
ATOM 1789 N N   . GLU C 3 61  ? 359.834 339.612 429.046 1.00 118.70 ? 61  GLU A N   1 
ATOM 1790 C CA  . GLU C 3 61  ? 360.445 339.328 430.331 1.00 118.70 ? 61  GLU A CA  1 
ATOM 1791 C C   . GLU C 3 61  ? 359.423 339.223 431.450 1.00 118.70 ? 61  GLU A C   1 
ATOM 1792 O O   . GLU C 3 61  ? 359.710 338.600 432.475 1.00 118.70 ? 61  GLU A O   1 
ATOM 1793 C CB  . GLU C 3 61  ? 361.475 340.400 430.670 1.00 118.70 ? 61  GLU A CB  1 
ATOM 1794 C CG  . GLU C 3 61  ? 362.557 339.921 431.602 1.00 118.70 ? 61  GLU A CG  1 
ATOM 1795 C CD  . GLU C 3 61  ? 363.653 340.935 431.767 1.00 118.70 ? 61  GLU A CD  1 
ATOM 1796 O OE1 . GLU C 3 61  ? 363.732 341.854 430.928 1.00 118.70 ? 61  GLU A OE1 1 
ATOM 1797 O OE2 . GLU C 3 61  ? 364.432 340.821 432.736 1.00 118.70 ? 61  GLU A OE2 1 
ATOM 1798 N N   . SER C 3 62  ? 358.237 339.792 431.276 1.00 106.34 ? 62  SER A N   1 
ATOM 1799 C CA  . SER C 3 62  ? 357.208 339.739 432.299 1.00 106.34 ? 62  SER A CA  1 
ATOM 1800 C C   . SER C 3 62  ? 356.372 338.476 432.222 1.00 106.34 ? 62  SER A C   1 
ATOM 1801 O O   . SER C 3 62  ? 355.391 338.356 432.958 1.00 106.34 ? 62  SER A O   1 
ATOM 1802 C CB  . SER C 3 62  ? 356.301 340.962 432.198 1.00 106.34 ? 62  SER A CB  1 
ATOM 1803 O OG  . SER C 3 62  ? 355.876 341.166 430.864 1.00 106.34 ? 62  SER A OG  1 
ATOM 1804 N N   . SER C 3 63  ? 356.729 337.541 431.347 1.00 101.25 ? 63  SER A N   1 
ATOM 1805 C CA  . SER C 3 63  ? 356.033 336.270 431.273 1.00 101.25 ? 63  SER A CA  1 
ATOM 1806 C C   . SER C 3 63  ? 356.300 335.440 432.521 1.00 101.25 ? 63  SER A C   1 
ATOM 1807 O O   . SER C 3 63  ? 357.258 335.675 433.260 1.00 101.25 ? 63  SER A O   1 
ATOM 1808 C CB  . SER C 3 63  ? 356.471 335.492 430.040 1.00 101.25 ? 63  SER A CB  1 
ATOM 1809 O OG  . SER C 3 63  ? 355.875 334.212 430.031 1.00 101.25 ? 63  SER A OG  1 
ATOM 1810 N N   . ILE C 3 64  ? 355.427 334.455 432.748 1.00 95.89  ? 64  ILE A N   1 
ATOM 1811 C CA  . ILE C 3 64  ? 355.521 333.626 433.944 1.00 95.89  ? 64  ILE A CA  1 
ATOM 1812 C C   . ILE C 3 64  ? 356.775 332.776 433.913 1.00 95.89  ? 64  ILE A C   1 
ATOM 1813 O O   . ILE C 3 64  ? 357.452 332.619 434.937 1.00 95.89  ? 64  ILE A O   1 
ATOM 1814 C CB  . ILE C 3 64  ? 354.261 332.758 434.084 1.00 95.89  ? 64  ILE A CB  1 
ATOM 1815 C CG1 . ILE C 3 64  ? 353.026 333.640 434.076 1.00 95.89  ? 64  ILE A CG1 1 
ATOM 1816 C CG2 . ILE C 3 64  ? 354.290 331.972 435.368 1.00 95.89  ? 64  ILE A CG2 1 
ATOM 1817 C CD1 . ILE C 3 64  ? 352.989 334.610 435.221 1.00 95.89  ? 64  ILE A CD1 1 
ATOM 1818 N N   . GLU C 3 65  ? 357.128 332.253 432.739 1.00 100.88 ? 65  GLU A N   1 
ATOM 1819 C CA  . GLU C 3 65  ? 358.313 331.417 432.612 1.00 100.88 ? 65  GLU A CA  1 
ATOM 1820 C C   . GLU C 3 65  ? 359.587 332.206 432.866 1.00 100.88 ? 65  GLU A C   1 
ATOM 1821 O O   . GLU C 3 65  ? 360.536 331.672 433.440 1.00 100.88 ? 65  GLU A O   1 
ATOM 1822 C CB  . GLU C 3 65  ? 358.343 330.778 431.228 1.00 100.88 ? 65  GLU A CB  1 
ATOM 1823 C CG  . GLU C 3 65  ? 359.391 329.707 431.058 1.00 100.88 ? 65  GLU A CG  1 
ATOM 1824 C CD  . GLU C 3 65  ? 359.146 328.515 431.948 1.00 100.88 ? 65  GLU A CD  1 
ATOM 1825 O OE1 . GLU C 3 65  ? 359.766 328.441 433.026 1.00 100.88 ? 65  GLU A OE1 1 
ATOM 1826 O OE2 . GLU C 3 65  ? 358.332 327.650 431.572 1.00 100.88 ? 65  GLU A OE2 1 
ATOM 1827 N N   . ASN C 3 66  ? 359.616 333.479 432.500 1.00 102.63 ? 66  ASN A N   1 
ATOM 1828 C CA  . ASN C 3 66  ? 360.746 334.330 432.830 1.00 102.63 ? 66  ASN A CA  1 
ATOM 1829 C C   . ASN C 3 66  ? 360.660 334.901 434.232 1.00 102.63 ? 66  ASN A C   1 
ATOM 1830 O O   . ASN C 3 66  ? 361.538 335.672 434.623 1.00 102.63 ? 66  ASN A O   1 
ATOM 1831 C CB  . ASN C 3 66  ? 360.862 335.471 431.826 1.00 102.63 ? 66  ASN A CB  1 
ATOM 1832 C CG  . ASN C 3 66  ? 361.322 335.002 430.477 1.00 102.63 ? 66  ASN A CG  1 
ATOM 1833 O OD1 . ASN C 3 66  ? 362.491 334.680 430.291 1.00 102.63 ? 66  ASN A OD1 1 
ATOM 1834 N ND2 . ASN C 3 66  ? 360.406 334.955 429.522 1.00 102.63 ? 66  ASN A ND2 1 
ATOM 1835 N N   . PHE C 3 67  ? 359.632 334.549 434.995 1.00 92.39  ? 67  PHE A N   1 
ATOM 1836 C CA  . PHE C 3 67  ? 359.457 335.090 436.332 1.00 92.39  ? 67  PHE A CA  1 
ATOM 1837 C C   . PHE C 3 67  ? 359.808 334.102 437.425 1.00 92.39  ? 67  PHE A C   1 
ATOM 1838 O O   . PHE C 3 67  ? 360.265 334.516 438.492 1.00 92.39  ? 67  PHE A O   1 
ATOM 1839 C CB  . PHE C 3 67  ? 358.013 335.546 436.522 1.00 92.39  ? 67  PHE A CB  1 
ATOM 1840 C CG  . PHE C 3 67  ? 357.763 336.247 437.815 1.00 92.39  ? 67  PHE A CG  1 
ATOM 1841 C CD1 . PHE C 3 67  ? 358.401 337.432 438.107 1.00 92.39  ? 67  PHE A CD1 1 
ATOM 1842 C CD2 . PHE C 3 67  ? 356.878 335.725 438.737 1.00 92.39  ? 67  PHE A CD2 1 
ATOM 1843 C CE1 . PHE C 3 67  ? 358.158 338.084 439.295 1.00 92.39  ? 67  PHE A CE1 1 
ATOM 1844 C CE2 . PHE C 3 67  ? 356.635 336.370 439.926 1.00 92.39  ? 67  PHE A CE2 1 
ATOM 1845 C CZ  . PHE C 3 67  ? 357.276 337.550 440.205 1.00 92.39  ? 67  PHE A CZ  1 
ATOM 1846 N N   . LEU C 3 68  ? 359.614 332.806 437.185 1.00 91.45  ? 68  LEU A N   1 
ATOM 1847 C CA  . LEU C 3 68  ? 359.827 331.799 438.210 1.00 91.45  ? 68  LEU A CA  1 
ATOM 1848 C C   . LEU C 3 68  ? 360.975 330.846 437.922 1.00 91.45  ? 68  LEU A C   1 
ATOM 1849 O O   . LEU C 3 68  ? 361.517 330.268 438.867 1.00 91.45  ? 68  LEU A O   1 
ATOM 1850 C CB  . LEU C 3 68  ? 358.550 330.980 438.413 1.00 91.45  ? 68  LEU A CB  1 
ATOM 1851 C CG  . LEU C 3 68  ? 357.352 331.836 438.790 1.00 91.45  ? 68  LEU A CG  1 
ATOM 1852 C CD1 . LEU C 3 68  ? 356.091 331.019 438.763 1.00 91.45  ? 68  LEU A CD1 1 
ATOM 1853 C CD2 . LEU C 3 68  ? 357.576 332.415 440.157 1.00 91.45  ? 68  LEU A CD2 1 
ATOM 1854 N N   . CYS C 3 69  ? 361.371 330.675 436.661 1.00 92.70  ? 69  CYS A N   1 
ATOM 1855 C CA  . CYS C 3 69  ? 362.420 329.720 436.297 1.00 92.70  ? 69  CYS A CA  1 
ATOM 1856 C C   . CYS C 3 69  ? 363.780 330.302 436.666 1.00 92.70  ? 69  CYS A C   1 
ATOM 1857 O O   . CYS C 3 69  ? 364.561 330.740 435.820 1.00 92.70  ? 69  CYS A O   1 
ATOM 1858 C CB  . CYS C 3 69  ? 362.341 329.384 434.816 1.00 92.70  ? 69  CYS A CB  1 
ATOM 1859 S SG  . CYS C 3 69  ? 363.380 328.037 434.250 1.00 92.70  ? 69  CYS A SG  1 
ATOM 1860 N N   . ARG C 3 70  ? 364.063 330.300 437.963 1.00 93.63  ? 70  ARG A N   1 
ATOM 1861 C CA  . ARG C 3 70  ? 365.327 330.754 438.513 1.00 93.63  ? 70  ARG A CA  1 
ATOM 1862 C C   . ARG C 3 70  ? 365.872 329.671 439.428 1.00 93.63  ? 70  ARG A C   1 
ATOM 1863 O O   . ARG C 3 70  ? 365.383 328.542 439.446 1.00 93.63  ? 70  ARG A O   1 
ATOM 1864 C CB  . ARG C 3 70  ? 365.169 332.069 439.281 1.00 93.63  ? 70  ARG A CB  1 
ATOM 1865 C CG  . ARG C 3 70  ? 364.597 333.207 438.465 1.00 93.63  ? 70  ARG A CG  1 
ATOM 1866 C CD  . ARG C 3 70  ? 365.499 333.557 437.306 1.00 93.63  ? 70  ARG A CD  1 
ATOM 1867 N NE  . ARG C 3 70  ? 365.129 334.832 436.706 1.00 93.63  ? 70  ARG A NE  1 
ATOM 1868 C CZ  . ARG C 3 70  ? 365.505 335.222 435.494 1.00 93.63  ? 70  ARG A CZ  1 
ATOM 1869 N NH1 . ARG C 3 70  ? 366.260 334.432 434.746 1.00 93.63  ? 70  ARG A NH1 1 
ATOM 1870 N NH2 . ARG C 3 70  ? 365.122 336.401 435.028 1.00 93.63  ? 70  ARG A NH2 1 
ATOM 1871 N N   . SER C 3 71  ? 366.900 330.012 440.191 1.00 91.26  ? 71  SER A N   1 
ATOM 1872 C CA  . SER C 3 71  ? 367.500 329.081 441.133 1.00 91.26  ? 71  SER A CA  1 
ATOM 1873 C C   . SER C 3 71  ? 367.823 329.789 442.439 1.00 91.26  ? 71  SER A C   1 
ATOM 1874 O O   . SER C 3 71  ? 368.210 330.960 442.440 1.00 91.26  ? 71  SER A O   1 
ATOM 1875 C CB  . SER C 3 71  ? 368.760 328.457 440.542 1.00 91.26  ? 71  SER A CB  1 
ATOM 1876 O OG  . SER C 3 71  ? 368.538 328.056 439.204 1.00 91.26  ? 71  SER A OG  1 
ATOM 1877 N N   . ALA C 3 72  ? 367.675 329.076 443.552 1.00 84.55  ? 72  ALA A N   1 
ATOM 1878 C CA  . ALA C 3 72  ? 367.904 329.679 444.853 1.00 84.55  ? 72  ALA A CA  1 
ATOM 1879 C C   . ALA C 3 72  ? 368.320 328.616 445.852 1.00 84.55  ? 72  ALA A C   1 
ATOM 1880 O O   . ALA C 3 72  ? 367.768 327.516 445.858 1.00 84.55  ? 72  ALA A O   1 
ATOM 1881 C CB  . ALA C 3 72  ? 366.651 330.396 445.349 1.00 84.55  ? 72  ALA A CB  1 
ATOM 1882 N N   . CYS C 3 73  ? 369.296 328.951 446.691 1.00 85.66  ? 73  CYS A N   1 
ATOM 1883 C CA  . CYS C 3 73  ? 369.707 328.068 447.775 1.00 85.66  ? 73  CYS A CA  1 
ATOM 1884 C C   . CYS C 3 73  ? 368.599 328.003 448.808 1.00 85.66  ? 73  CYS A C   1 
ATOM 1885 O O   . CYS C 3 73  ? 368.341 328.985 449.507 1.00 85.66  ? 73  CYS A O   1 
ATOM 1886 C CB  . CYS C 3 73  ? 370.998 328.574 448.409 1.00 85.66  ? 73  CYS A CB  1 
ATOM 1887 S SG  . CYS C 3 73  ? 371.359 327.914 450.045 1.00 85.66  ? 73  CYS A SG  1 
ATOM 1888 N N   . VAL C 3 74  ? 367.935 326.855 448.907 1.00 81.36  ? 74  VAL A N   1 
ATOM 1889 C CA  . VAL C 3 74  ? 366.766 326.735 449.754 1.00 81.36  ? 74  VAL A CA  1 
ATOM 1890 C C   . VAL C 3 74  ? 367.029 325.931 451.020 1.00 81.36  ? 74  VAL A C   1 
ATOM 1891 O O   . VAL C 3 74  ? 366.175 325.916 451.912 1.00 81.36  ? 74  VAL A O   1 
ATOM 1892 C CB  . VAL C 3 74  ? 365.589 326.134 448.970 1.00 81.36  ? 74  VAL A CB  1 
ATOM 1893 C CG1 . VAL C 3 74  ? 365.168 327.073 447.888 1.00 81.36  ? 74  VAL A CG1 1 
ATOM 1894 C CG2 . VAL C 3 74  ? 365.994 324.823 448.383 1.00 81.36  ? 74  VAL A CG2 1 
ATOM 1895 N N   . TYR C 3 75  ? 368.171 325.267 451.134 1.00 84.67  ? 75  TYR A N   1 
ATOM 1896 C CA  . TYR C 3 75  ? 368.501 324.547 452.351 1.00 84.67  ? 75  TYR A CA  1 
ATOM 1897 C C   . TYR C 3 75  ? 370.008 324.455 452.482 1.00 84.67  ? 75  TYR A C   1 
ATOM 1898 O O   . TYR C 3 75  ? 370.735 324.559 451.495 1.00 84.67  ? 75  TYR A O   1 
ATOM 1899 C CB  . TYR C 3 75  ? 367.899 323.149 452.365 1.00 84.67  ? 75  TYR A CB  1 
ATOM 1900 C CG  . TYR C 3 75  ? 367.832 322.558 453.742 1.00 84.67  ? 75  TYR A CG  1 
ATOM 1901 C CD1 . TYR C 3 75  ? 367.233 323.252 454.781 1.00 84.67  ? 75  TYR A CD1 1 
ATOM 1902 C CD2 . TYR C 3 75  ? 368.390 321.321 454.011 1.00 84.67  ? 75  TYR A CD2 1 
ATOM 1903 C CE1 . TYR C 3 75  ? 367.174 322.723 456.049 1.00 84.67  ? 75  TYR A CE1 1 
ATOM 1904 C CE2 . TYR C 3 75  ? 368.334 320.781 455.273 1.00 84.67  ? 75  TYR A CE2 1 
ATOM 1905 C CZ  . TYR C 3 75  ? 367.728 321.488 456.290 1.00 84.67  ? 75  TYR A CZ  1 
ATOM 1906 O OH  . TYR C 3 75  ? 367.674 320.953 457.555 1.00 84.67  ? 75  TYR A OH  1 
ATOM 1907 N N   . TYR C 3 76  ? 370.468 324.243 453.711 1.00 87.79  ? 76  TYR A N   1 
ATOM 1908 C CA  . TYR C 3 76  ? 371.898 324.228 453.997 1.00 87.79  ? 76  TYR A CA  1 
ATOM 1909 C C   . TYR C 3 76  ? 372.093 323.465 455.298 1.00 87.79  ? 76  TYR A C   1 
ATOM 1910 O O   . TYR C 3 76  ? 371.675 323.939 456.356 1.00 87.79  ? 76  TYR A O   1 
ATOM 1911 C CB  . TYR C 3 76  ? 372.422 325.652 454.089 1.00 87.79  ? 76  TYR A CB  1 
ATOM 1912 C CG  . TYR C 3 76  ? 373.667 325.825 454.906 1.00 87.79  ? 76  TYR A CG  1 
ATOM 1913 C CD1 . TYR C 3 76  ? 374.877 325.309 454.477 1.00 87.79  ? 76  TYR A CD1 1 
ATOM 1914 C CD2 . TYR C 3 76  ? 373.636 326.527 456.098 1.00 87.79  ? 76  TYR A CD2 1 
ATOM 1915 C CE1 . TYR C 3 76  ? 376.023 325.475 455.220 1.00 87.79  ? 76  TYR A CE1 1 
ATOM 1916 C CE2 . TYR C 3 76  ? 374.774 326.698 456.848 1.00 87.79  ? 76  TYR A CE2 1 
ATOM 1917 C CZ  . TYR C 3 76  ? 375.965 326.170 456.404 1.00 87.79  ? 76  TYR A CZ  1 
ATOM 1918 O OH  . TYR C 3 76  ? 377.105 326.339 457.149 1.00 87.79  ? 76  TYR A OH  1 
ATOM 1919 N N   . ALA C 3 77  ? 372.711 322.290 455.224 1.00 87.69  ? 77  ALA A N   1 
ATOM 1920 C CA  . ALA C 3 77  ? 372.835 321.428 456.388 1.00 87.69  ? 77  ALA A CA  1 
ATOM 1921 C C   . ALA C 3 77  ? 374.179 320.724 456.379 1.00 87.69  ? 77  ALA A C   1 
ATOM 1922 O O   . ALA C 3 77  ? 374.787 320.518 455.329 1.00 87.69  ? 77  ALA A O   1 
ATOM 1923 C CB  . ALA C 3 77  ? 371.719 320.388 456.435 1.00 87.69  ? 77  ALA A CB  1 
ATOM 1924 N N   . THR C 3 78  ? 374.635 320.348 457.569 1.00 91.43  ? 78  THR A N   1 
ATOM 1925 C CA  . THR C 3 78  ? 375.886 319.628 457.738 1.00 91.43  ? 78  THR A CA  1 
ATOM 1926 C C   . THR C 3 78  ? 375.610 318.251 458.319 1.00 91.43  ? 78  THR A C   1 
ATOM 1927 O O   . THR C 3 78  ? 374.543 318.006 458.885 1.00 91.43  ? 78  THR A O   1 
ATOM 1928 C CB  . THR C 3 78  ? 376.855 320.367 458.665 1.00 91.43  ? 78  THR A CB  1 
ATOM 1929 O OG1 . THR C 3 78  ? 376.420 320.219 460.020 1.00 91.43  ? 78  THR A OG1 1 
ATOM 1930 C CG2 . THR C 3 78  ? 376.907 321.836 458.331 1.00 91.43  ? 78  THR A CG2 1 
ATOM 1931 N N   . TYR C 3 79  ? 376.590 317.359 458.185 1.00 87.90  ? 79  TYR A N   1 
ATOM 1932 C CA  . TYR C 3 79  ? 376.530 316.041 458.794 1.00 87.90  ? 79  TYR A CA  1 
ATOM 1933 C C   . TYR C 3 79  ? 377.930 315.464 458.874 1.00 87.90  ? 79  TYR A C   1 
ATOM 1934 O O   . TYR C 3 79  ? 378.725 315.627 457.950 1.00 87.90  ? 79  TYR A O   1 
ATOM 1935 C CB  . TYR C 3 79  ? 375.627 315.085 458.018 1.00 87.90  ? 79  TYR A CB  1 
ATOM 1936 C CG  . TYR C 3 79  ? 375.890 314.992 456.538 1.00 87.90  ? 79  TYR A CG  1 
ATOM 1937 C CD1 . TYR C 3 79  ? 375.258 315.841 455.649 1.00 87.90  ? 79  TYR A CD1 1 
ATOM 1938 C CD2 . TYR C 3 79  ? 376.726 314.016 456.025 1.00 87.90  ? 79  TYR A CD2 1 
ATOM 1939 C CE1 . TYR C 3 79  ? 375.476 315.740 454.297 1.00 87.90  ? 79  TYR A CE1 1 
ATOM 1940 C CE2 . TYR C 3 79  ? 376.947 313.911 454.675 1.00 87.90  ? 79  TYR A CE2 1 
ATOM 1941 C CZ  . TYR C 3 79  ? 376.321 314.774 453.819 1.00 87.90  ? 79  TYR A CZ  1 
ATOM 1942 O OH  . TYR C 3 79  ? 376.545 314.667 452.473 1.00 87.90  ? 79  TYR A OH  1 
ATOM 1943 N N   . THR C 3 80  ? 378.220 314.792 459.978 1.00 97.60  ? 80  THR A N   1 
ATOM 1944 C CA  . THR C 3 80  ? 379.500 314.138 460.188 1.00 97.60  ? 80  THR A CA  1 
ATOM 1945 C C   . THR C 3 80  ? 379.328 312.629 460.038 1.00 97.60  ? 80  THR A C   1 
ATOM 1946 O O   . THR C 3 80  ? 378.299 312.059 460.397 1.00 97.60  ? 80  THR A O   1 
ATOM 1947 C CB  . THR C 3 80  ? 380.050 314.499 461.570 1.00 97.60  ? 80  THR A CB  1 
ATOM 1948 O OG1 . THR C 3 80  ? 379.904 315.906 461.775 1.00 97.60  ? 80  THR A OG1 1 
ATOM 1949 C CG2 . THR C 3 80  ? 381.519 314.170 461.679 1.00 97.60  ? 80  THR A CG2 1 
ATOM 1950 N N   . ASN C 3 81  ? 380.356 311.981 459.497 1.00 102.39 ? 81  ASN A N   1 
ATOM 1951 C CA  . ASN C 3 81  ? 380.271 310.581 459.109 1.00 102.39 ? 81  ASN A CA  1 
ATOM 1952 C C   . ASN C 3 81  ? 380.307 309.615 460.282 1.00 102.39 ? 81  ASN A C   1 
ATOM 1953 O O   . ASN C 3 81  ? 379.782 308.506 460.171 1.00 102.39 ? 81  ASN A O   1 
ATOM 1954 C CB  . ASN C 3 81  ? 381.411 310.233 458.153 1.00 102.39 ? 81  ASN A CB  1 
ATOM 1955 C CG  . ASN C 3 81  ? 382.767 310.373 458.795 1.00 102.39 ? 81  ASN A CG  1 
ATOM 1956 O OD1 . ASN C 3 81  ? 382.941 311.124 459.752 1.00 102.39 ? 81  ASN A OD1 1 
ATOM 1957 N ND2 . ASN C 3 81  ? 383.742 309.652 458.267 1.00 102.39 ? 81  ASN A ND2 1 
ATOM 1958 N N   . ASN C 3 82  ? 380.916 309.992 461.400 1.00 109.74 ? 82  ASN A N   1 
ATOM 1959 C CA  . ASN C 3 82  ? 381.205 309.011 462.434 1.00 109.74 ? 82  ASN A CA  1 
ATOM 1960 C C   . ASN C 3 82  ? 380.383 309.179 463.703 1.00 109.74 ? 82  ASN A C   1 
ATOM 1961 O O   . ASN C 3 82  ? 380.519 308.359 464.614 1.00 109.74 ? 82  ASN A O   1 
ATOM 1962 C CB  . ASN C 3 82  ? 382.687 309.062 462.801 1.00 109.74 ? 82  ASN A CB  1 
ATOM 1963 C CG  . ASN C 3 82  ? 383.049 310.314 463.562 1.00 109.74 ? 82  ASN A CG  1 
ATOM 1964 O OD1 . ASN C 3 82  ? 382.554 311.398 463.261 1.00 109.74 ? 82  ASN A OD1 1 
ATOM 1965 N ND2 . ASN C 3 82  ? 383.911 310.173 464.560 1.00 109.74 ? 82  ASN A ND2 1 
ATOM 1966 N N   . SER C 3 83  ? 379.536 310.198 463.794 1.00 111.12 ? 83  SER A N   1 
ATOM 1967 C CA  . SER C 3 83  ? 378.866 310.505 465.054 1.00 111.12 ? 83  SER A CA  1 
ATOM 1968 C C   . SER C 3 83  ? 377.703 309.572 465.368 1.00 111.12 ? 83  SER A C   1 
ATOM 1969 O O   . SER C 3 83  ? 377.097 309.724 466.436 1.00 111.12 ? 83  SER A O   1 
ATOM 1970 C CB  . SER C 3 83  ? 378.364 311.951 465.047 1.00 111.12 ? 83  SER A CB  1 
ATOM 1971 O OG  . SER C 3 83  ? 377.305 312.129 464.121 1.00 111.12 ? 83  SER A OG  1 
ATOM 1972 N N   . LYS C 3 84  ? 377.366 308.649 464.459 1.00 108.94 ? 84  LYS A N   1 
ATOM 1973 C CA  . LYS C 3 84  ? 376.226 307.727 464.500 1.00 108.94 ? 84  LYS A CA  1 
ATOM 1974 C C   . LYS C 3 84  ? 374.867 308.431 464.536 1.00 108.94 ? 84  LYS A C   1 
ATOM 1975 O O   . LYS C 3 84  ? 373.845 307.776 464.774 1.00 108.94 ? 84  LYS A O   1 
ATOM 1976 C CB  . LYS C 3 84  ? 376.324 306.727 465.666 1.00 108.94 ? 84  LYS A CB  1 
ATOM 1977 C CG  . LYS C 3 84  ? 377.706 306.121 465.870 1.00 108.94 ? 84  LYS A CG  1 
ATOM 1978 C CD  . LYS C 3 84  ? 377.759 305.245 467.112 1.00 108.94 ? 84  LYS A CD  1 
ATOM 1979 C CE  . LYS C 3 84  ? 376.743 304.124 467.040 1.00 108.94 ? 84  LYS A CE  1 
ATOM 1980 N NZ  . LYS C 3 84  ? 377.008 303.228 465.885 1.00 108.94 ? 84  LYS A NZ  1 
ATOM 1981 N N   . LYS C 3 85  ? 374.824 309.749 464.313 1.00 104.53 ? 85  LYS A N   1 
ATOM 1982 C CA  . LYS C 3 85  ? 373.594 310.492 464.079 1.00 104.53 ? 85  LYS A CA  1 
ATOM 1983 C C   . LYS C 3 85  ? 373.818 311.573 463.033 1.00 104.53 ? 85  LYS A C   1 
ATOM 1984 O O   . LYS C 3 85  ? 373.123 312.593 463.029 1.00 104.53 ? 85  LYS A O   1 
ATOM 1985 C CB  . LYS C 3 85  ? 373.058 311.113 465.364 1.00 104.53 ? 85  LYS A CB  1 
ATOM 1986 C CG  . LYS C 3 85  ? 374.062 311.964 466.104 1.00 104.53 ? 85  LYS A CG  1 
ATOM 1987 C CD  . LYS C 3 85  ? 373.384 312.722 467.226 1.00 104.53 ? 85  LYS A CD  1 
ATOM 1988 C CE  . LYS C 3 85  ? 374.382 313.539 468.023 1.00 104.53 ? 85  LYS A CE  1 
ATOM 1989 N NZ  . LYS C 3 85  ? 373.730 314.217 469.173 1.00 104.53 ? 85  LYS A NZ  1 
ATOM 1990 N N   . GLY C 3 86  ? 374.798 311.377 462.160 1.00 91.91  ? 86  GLY A N   1 
ATOM 1991 C CA  . GLY C 3 86  ? 375.064 312.340 461.118 1.00 91.91  ? 86  GLY A CA  1 
ATOM 1992 C C   . GLY C 3 86  ? 374.480 311.954 459.778 1.00 91.91  ? 86  GLY A C   1 
ATOM 1993 O O   . GLY C 3 86  ? 375.066 311.154 459.047 1.00 91.91  ? 86  GLY A O   1 
ATOM 1994 N N   . PHE C 3 87  ? 373.328 312.530 459.451 1.00 83.02  ? 87  PHE A N   1 
ATOM 1995 C CA  . PHE C 3 87  ? 372.725 312.418 458.133 1.00 83.02  ? 87  PHE A CA  1 
ATOM 1996 C C   . PHE C 3 87  ? 371.740 313.563 457.980 1.00 83.02  ? 87  PHE A C   1 
ATOM 1997 O O   . PHE C 3 87  ? 371.019 313.893 458.921 1.00 83.02  ? 87  PHE A O   1 
ATOM 1998 C CB  . PHE C 3 87  ? 372.033 311.066 457.919 1.00 83.02  ? 87  PHE A CB  1 
ATOM 1999 C CG  . PHE C 3 87  ? 370.817 310.853 458.760 1.00 83.02  ? 87  PHE A CG  1 
ATOM 2000 C CD1 . PHE C 3 87  ? 370.932 310.465 460.077 1.00 83.02  ? 87  PHE A CD1 1 
ATOM 2001 C CD2 . PHE C 3 87  ? 369.558 311.011 458.222 1.00 83.02  ? 87  PHE A CD2 1 
ATOM 2002 C CE1 . PHE C 3 87  ? 369.815 310.264 460.849 1.00 83.02  ? 87  PHE A CE1 1 
ATOM 2003 C CE2 . PHE C 3 87  ? 368.440 310.812 458.988 1.00 83.02  ? 87  PHE A CE2 1 
ATOM 2004 C CZ  . PHE C 3 87  ? 368.569 310.436 460.303 1.00 83.02  ? 87  PHE A CZ  1 
ATOM 2005 N N   . ALA C 3 88  ? 371.726 314.176 456.806 1.00 85.82  ? 88  ALA A N   1 
ATOM 2006 C CA  . ALA C 3 88  ? 370.863 315.323 456.600 1.00 85.82  ? 88  ALA A CA  1 
ATOM 2007 C C   . ALA C 3 88  ? 369.461 314.861 456.229 1.00 85.82  ? 88  ALA A C   1 
ATOM 2008 O O   . ALA C 3 88  ? 369.236 313.708 455.859 1.00 85.82  ? 88  ALA A O   1 
ATOM 2009 C CB  . ALA C 3 88  ? 371.439 316.238 455.528 1.00 85.82  ? 88  ALA A CB  1 
ATOM 2010 N N   . GLU C 3 89  ? 368.507 315.783 456.313 1.00 89.99  ? 89  GLU A N   1 
ATOM 2011 C CA  . GLU C 3 89  ? 367.103 315.451 456.123 1.00 89.99  ? 89  GLU A CA  1 
ATOM 2012 C C   . GLU C 3 89  ? 366.336 316.730 455.849 1.00 89.99  ? 89  GLU A C   1 
ATOM 2013 O O   . GLU C 3 89  ? 366.342 317.639 456.680 1.00 89.99  ? 89  GLU A O   1 
ATOM 2014 C CB  . GLU C 3 89  ? 366.542 314.760 457.362 1.00 89.99  ? 89  GLU A CB  1 
ATOM 2015 C CG  . GLU C 3 89  ? 365.054 314.562 457.345 1.00 89.99  ? 89  GLU A CG  1 
ATOM 2016 C CD  . GLU C 3 89  ? 364.618 313.519 458.351 1.00 89.99  ? 89  GLU A CD  1 
ATOM 2017 O OE1 . GLU C 3 89  ? 365.291 313.383 459.393 1.00 89.99  ? 89  GLU A OE1 1 
ATOM 2018 O OE2 . GLU C 3 89  ? 363.624 312.812 458.085 1.00 89.99  ? 89  GLU A OE2 1 
ATOM 2019 N N   . TRP C 3 90  ? 365.667 316.796 454.704 1.00 82.69  ? 90  TRP A N   1 
ATOM 2020 C CA  . TRP C 3 90  ? 364.934 318.006 454.355 1.00 82.69  ? 90  TRP A CA  1 
ATOM 2021 C C   . TRP C 3 90  ? 363.619 317.622 453.709 1.00 82.69  ? 90  TRP A C   1 
ATOM 2022 O O   . TRP C 3 90  ? 363.612 316.908 452.705 1.00 82.69  ? 90  TRP A O   1 
ATOM 2023 C CB  . TRP C 3 90  ? 365.738 318.882 453.417 1.00 82.69  ? 90  TRP A CB  1 
ATOM 2024 C CG  . TRP C 3 90  ? 364.970 320.058 452.962 1.00 82.69  ? 90  TRP A CG  1 
ATOM 2025 C CD1 . TRP C 3 90  ? 364.360 320.978 453.747 1.00 82.69  ? 90  TRP A CD1 1 
ATOM 2026 C CD2 . TRP C 3 90  ? 364.713 320.447 451.613 1.00 82.69  ? 90  TRP A CD2 1 
ATOM 2027 N NE1 . TRP C 3 90  ? 363.741 321.925 452.975 1.00 82.69  ? 90  TRP A NE1 1 
ATOM 2028 C CE2 . TRP C 3 90  ? 363.946 321.619 451.657 1.00 82.69  ? 90  TRP A CE2 1 
ATOM 2029 C CE3 . TRP C 3 90  ? 365.061 319.920 450.371 1.00 82.69  ? 90  TRP A CE3 1 
ATOM 2030 C CZ2 . TRP C 3 90  ? 363.519 322.271 450.511 1.00 82.69  ? 90  TRP A CZ2 1 
ATOM 2031 C CZ3 . TRP C 3 90  ? 364.637 320.569 449.237 1.00 82.69  ? 90  TRP A CZ3 1 
ATOM 2032 C CH2 . TRP C 3 90  ? 363.876 321.730 449.313 1.00 82.69  ? 90  TRP A CH2 1 
ATOM 2033 N N   . VAL C 3 91  ? 362.517 318.091 454.279 1.00 82.51  ? 91  VAL A N   1 
ATOM 2034 C CA  . VAL C 3 91  ? 361.208 317.921 453.665 1.00 82.51  ? 91  VAL A CA  1 
ATOM 2035 C C   . VAL C 3 91  ? 361.079 318.959 452.564 1.00 82.51  ? 91  VAL A C   1 
ATOM 2036 O O   . VAL C 3 91  ? 361.404 320.131 452.768 1.00 82.51  ? 91  VAL A O   1 
ATOM 2037 C CB  . VAL C 3 91  ? 360.089 318.069 454.702 1.00 82.51  ? 91  VAL A CB  1 
ATOM 2038 C CG1 . VAL C 3 91  ? 358.750 317.739 454.088 1.00 82.51  ? 91  VAL A CG1 1 
ATOM 2039 C CG2 . VAL C 3 91  ? 360.363 317.176 455.887 1.00 82.51  ? 91  VAL A CG2 1 
ATOM 2040 N N   . ILE C 3 92  ? 360.620 318.533 451.392 1.00 83.60  ? 92  ILE A N   1 
ATOM 2041 C CA  . ILE C 3 92  ? 360.534 319.446 450.262 1.00 83.60  ? 92  ILE A CA  1 
ATOM 2042 C C   . ILE C 3 92  ? 359.273 320.283 450.395 1.00 83.60  ? 92  ILE A C   1 
ATOM 2043 O O   . ILE C 3 92  ? 358.166 319.747 450.509 1.00 83.60  ? 92  ILE A O   1 
ATOM 2044 C CB  . ILE C 3 92  ? 360.548 318.680 448.941 1.00 83.60  ? 92  ILE A CB  1 
ATOM 2045 C CG1 . ILE C 3 92  ? 361.861 317.931 448.796 1.00 83.60  ? 92  ILE A CG1 1 
ATOM 2046 C CG2 . ILE C 3 92  ? 360.376 319.625 447.788 1.00 83.60  ? 92  ILE A CG2 1 
ATOM 2047 C CD1 . ILE C 3 92  ? 361.868 316.984 447.646 1.00 83.60  ? 92  ILE A CD1 1 
ATOM 2048 N N   . ASN C 3 93  ? 359.436 321.602 450.385 1.00 88.78  ? 93  ASN A N   1 
ATOM 2049 C CA  . ASN C 3 93  ? 358.320 322.528 450.359 1.00 88.78  ? 93  ASN A CA  1 
ATOM 2050 C C   . ASN C 3 93  ? 358.806 323.832 449.753 1.00 88.78  ? 93  ASN A C   1 
ATOM 2051 O O   . ASN C 3 93  ? 359.987 323.990 449.442 1.00 88.78  ? 93  ASN A O   1 
ATOM 2052 C CB  . ASN C 3 93  ? 357.740 322.750 451.756 1.00 88.78  ? 93  ASN A CB  1 
ATOM 2053 C CG  . ASN C 3 93  ? 358.755 323.305 452.718 1.00 88.78  ? 93  ASN A CG  1 
ATOM 2054 O OD1 . ASN C 3 93  ? 359.956 323.110 452.547 1.00 88.78  ? 93  ASN A OD1 1 
ATOM 2055 N ND2 . ASN C 3 93  ? 358.280 323.992 453.748 1.00 88.78  ? 93  ASN A ND2 1 
ATOM 2056 N N   . THR C 3 94  ? 357.889 324.777 449.591 1.00 93.46  ? 94  THR A N   1 
ATOM 2057 C CA  . THR C 3 94  ? 358.225 326.077 449.035 1.00 93.46  ? 94  THR A CA  1 
ATOM 2058 C C   . THR C 3 94  ? 358.301 327.169 450.084 1.00 93.46  ? 94  THR A C   1 
ATOM 2059 O O   . THR C 3 94  ? 358.853 328.234 449.804 1.00 93.46  ? 94  THR A O   1 
ATOM 2060 C CB  . THR C 3 94  ? 357.198 326.491 447.978 1.00 93.46  ? 94  THR A CB  1 
ATOM 2061 O OG1 . THR C 3 94  ? 356.045 327.039 448.628 1.00 93.46  ? 94  THR A OG1 1 
ATOM 2062 C CG2 . THR C 3 94  ? 356.782 325.296 447.142 1.00 93.46  ? 94  THR A CG2 1 
ATOM 2063 N N   . ARG C 3 95  ? 357.783 326.930 451.285 1.00 95.54  ? 95  ARG A N   1 
ATOM 2064 C CA  . ARG C 3 95  ? 357.644 327.973 452.292 1.00 95.54  ? 95  ARG A CA  1 
ATOM 2065 C C   . ARG C 3 95  ? 358.886 328.128 453.154 1.00 95.54  ? 95  ARG A C   1 
ATOM 2066 O O   . ARG C 3 95  ? 358.796 328.645 454.274 1.00 95.54  ? 95  ARG A O   1 
ATOM 2067 C CB  . ARG C 3 95  ? 356.425 327.686 453.168 1.00 95.54  ? 95  ARG A CB  1 
ATOM 2068 C CG  . ARG C 3 95  ? 355.332 326.928 452.444 1.00 95.54  ? 95  ARG A CG  1 
ATOM 2069 C CD  . ARG C 3 95  ? 354.013 326.984 453.186 1.00 95.54  ? 95  ARG A CD  1 
ATOM 2070 N NE  . ARG C 3 95  ? 352.895 326.782 452.272 1.00 95.54  ? 95  ARG A NE  1 
ATOM 2071 C CZ  . ARG C 3 95  ? 351.663 327.229 452.482 1.00 95.54  ? 95  ARG A CZ  1 
ATOM 2072 N NH1 . ARG C 3 95  ? 351.378 327.912 453.580 1.00 95.54  ? 95  ARG A NH1 1 
ATOM 2073 N NH2 . ARG C 3 95  ? 350.713 326.997 451.589 1.00 95.54  ? 95  ARG A NH2 1 
ATOM 2074 N N   . GLN C 3 96  ? 360.049 327.707 452.665 1.00 98.12  ? 96  GLN A N   1 
ATOM 2075 C CA  . GLN C 3 96  ? 361.249 327.744 453.487 1.00 98.12  ? 96  GLN A CA  1 
ATOM 2076 C C   . GLN C 3 96  ? 361.855 329.140 453.513 1.00 98.12  ? 96  GLN A C   1 
ATOM 2077 O O   . GLN C 3 96  ? 361.864 329.800 454.554 1.00 98.12  ? 96  GLN A O   1 
ATOM 2078 C CB  . GLN C 3 96  ? 362.268 326.729 452.969 1.00 98.12  ? 96  GLN A CB  1 
ATOM 2079 C CG  . GLN C 3 96  ? 363.252 326.272 454.014 1.00 98.12  ? 96  GLN A CG  1 
ATOM 2080 C CD  . GLN C 3 96  ? 362.610 325.374 455.038 1.00 98.12  ? 96  GLN A CD  1 
ATOM 2081 O OE1 . GLN C 3 96  ? 362.775 325.567 456.240 1.00 98.12  ? 96  GLN A OE1 1 
ATOM 2082 N NE2 . GLN C 3 96  ? 361.870 324.381 454.567 1.00 98.12  ? 96  GLN A NE2 1 
ATOM 2083 N N   . VAL C 3 97  ? 362.326 329.609 452.382 1.00 96.32  ? 97  VAL A N   1 
ATOM 2084 C CA  . VAL C 3 97  ? 362.933 330.926 452.295 1.00 96.32  ? 97  VAL A CA  1 
ATOM 2085 C C   . VAL C 3 97  ? 361.840 331.914 451.921 1.00 96.32  ? 97  VAL A C   1 
ATOM 2086 O O   . VAL C 3 97  ? 360.851 331.560 451.272 1.00 96.32  ? 97  VAL A O   1 
ATOM 2087 C CB  . VAL C 3 97  ? 364.119 330.918 451.301 1.00 96.32  ? 97  VAL A CB  1 
ATOM 2088 C CG1 . VAL C 3 97  ? 363.657 330.789 449.872 1.00 96.32  ? 97  VAL A CG1 1 
ATOM 2089 C CG2 . VAL C 3 97  ? 365.012 332.135 451.485 1.00 96.32  ? 97  VAL A CG2 1 
ATOM 2090 N N   . ALA C 3 98  ? 361.976 333.153 452.390 1.00 93.34  ? 98  ALA A N   1 
ATOM 2091 C CA  . ALA C 3 98  ? 360.911 334.129 452.218 1.00 93.34  ? 98  ALA A CA  1 
ATOM 2092 C C   . ALA C 3 98  ? 360.784 334.628 450.790 1.00 93.34  ? 98  ALA A C   1 
ATOM 2093 O O   . ALA C 3 98  ? 359.660 334.805 450.315 1.00 93.34  ? 98  ALA A O   1 
ATOM 2094 C CB  . ALA C 3 98  ? 361.132 335.320 453.147 1.00 93.34  ? 98  ALA A CB  1 
ATOM 2095 N N   . GLN C 3 99  ? 361.902 334.843 450.099 1.00 96.91  ? 99  GLN A N   1 
ATOM 2096 C CA  . GLN C 3 99  ? 361.862 335.478 448.788 1.00 96.91  ? 99  GLN A CA  1 
ATOM 2097 C C   . GLN C 3 99  ? 361.252 334.573 447.730 1.00 96.91  ? 99  GLN A C   1 
ATOM 2098 O O   . GLN C 3 99  ? 360.543 335.052 446.841 1.00 96.91  ? 99  GLN A O   1 
ATOM 2099 C CB  . GLN C 3 99  ? 363.263 335.904 448.363 1.00 96.91  ? 99  GLN A CB  1 
ATOM 2100 C CG  . GLN C 3 99  ? 363.625 337.315 448.767 1.00 96.91  ? 99  GLN A CG  1 
ATOM 2101 C CD  . GLN C 3 99  ? 363.055 338.358 447.830 1.00 96.91  ? 99  GLN A CD  1 
ATOM 2102 O OE1 . GLN C 3 99  ? 362.432 338.032 446.822 1.00 96.91  ? 99  GLN A OE1 1 
ATOM 2103 N NE2 . GLN C 3 99  ? 363.275 339.624 448.155 1.00 96.91  ? 99  GLN A NE2 1 
ATOM 2104 N N   . LEU C 3 100 ? 361.512 333.269 447.801 1.00 90.93  ? 100 LEU A N   1 
ATOM 2105 C CA  . LEU C 3 100 ? 360.832 332.356 446.895 1.00 90.93  ? 100 LEU A CA  1 
ATOM 2106 C C   . LEU C 3 100 ? 359.378 332.180 447.290 1.00 90.93  ? 100 LEU A C   1 
ATOM 2107 O O   . LEU C 3 100 ? 358.536 331.883 446.437 1.00 90.93  ? 100 LEU A O   1 
ATOM 2108 C CB  . LEU C 3 100 ? 361.534 331.005 446.875 1.00 90.93  ? 100 LEU A CB  1 
ATOM 2109 C CG  . LEU C 3 100 ? 361.138 330.071 445.739 1.00 90.93  ? 100 LEU A CG  1 
ATOM 2110 C CD1 . LEU C 3 100 ? 361.617 330.639 444.427 1.00 90.93  ? 100 LEU A CD1 1 
ATOM 2111 C CD2 . LEU C 3 100 ? 361.684 328.679 445.966 1.00 90.93  ? 100 LEU A CD2 1 
ATOM 2112 N N   . ARG C 3 101 ? 359.064 332.371 448.569 1.00 92.90  ? 101 ARG A N   1 
ATOM 2113 C CA  . ARG C 3 101 ? 357.691 332.198 449.013 1.00 92.90  ? 101 ARG A CA  1 
ATOM 2114 C C   . ARG C 3 101 ? 356.801 333.309 448.491 1.00 92.90  ? 101 ARG A C   1 
ATOM 2115 O O   . ARG C 3 101 ? 355.732 333.039 447.939 1.00 92.90  ? 101 ARG A O   1 
ATOM 2116 C CB  . ARG C 3 101 ? 357.631 332.148 450.531 1.00 92.90  ? 101 ARG A CB  1 
ATOM 2117 C CG  . ARG C 3 101 ? 356.245 331.910 451.066 1.00 92.90  ? 101 ARG A CG  1 
ATOM 2118 C CD  . ARG C 3 101 ? 356.301 331.554 452.530 1.00 92.90  ? 101 ARG A CD  1 
ATOM 2119 N NE  . ARG C 3 101 ? 354.973 331.419 453.107 1.00 92.90  ? 101 ARG A NE  1 
ATOM 2120 C CZ  . ARG C 3 101 ? 354.752 331.111 454.375 1.00 92.90  ? 101 ARG A CZ  1 
ATOM 2121 N NH1 . ARG C 3 101 ? 355.773 330.914 455.191 1.00 92.90  ? 101 ARG A NH1 1 
ATOM 2122 N NH2 . ARG C 3 101 ? 353.514 331.010 454.830 1.00 92.90  ? 101 ARG A NH2 1 
ATOM 2123 N N   . ARG C 3 102 ? 357.247 334.557 448.621 1.00 93.00  ? 102 ARG A N   1 
ATOM 2124 C CA  . ARG C 3 102 ? 356.405 335.693 448.269 1.00 93.00  ? 102 ARG A CA  1 
ATOM 2125 C C   . ARG C 3 102 ? 356.156 335.778 446.773 1.00 93.00  ? 102 ARG A C   1 
ATOM 2126 O O   . ARG C 3 102 ? 355.082 336.212 446.352 1.00 93.00  ? 102 ARG A O   1 
ATOM 2127 C CB  . ARG C 3 102 ? 357.039 336.982 448.769 1.00 93.00  ? 102 ARG A CB  1 
ATOM 2128 C CG  . ARG C 3 102 ? 356.100 338.151 448.781 1.00 93.00  ? 102 ARG A CG  1 
ATOM 2129 C CD  . ARG C 3 102 ? 356.807 339.399 449.226 1.00 93.00  ? 102 ARG A CD  1 
ATOM 2130 N NE  . ARG C 3 102 ? 355.952 340.560 449.062 1.00 93.00  ? 102 ARG A NE  1 
ATOM 2131 C CZ  . ARG C 3 102 ? 355.841 341.241 447.931 1.00 93.00  ? 102 ARG A CZ  1 
ATOM 2132 N NH1 . ARG C 3 102 ? 356.536 340.885 446.864 1.00 93.00  ? 102 ARG A NH1 1 
ATOM 2133 N NH2 . ARG C 3 102 ? 355.035 342.283 447.870 1.00 93.00  ? 102 ARG A NH2 1 
ATOM 2134 N N   . LYS C 3 103 ? 357.108 335.347 445.957 1.00 88.96  ? 103 LYS A N   1 
ATOM 2135 C CA  . LYS C 3 103 ? 356.843 335.279 444.531 1.00 88.96  ? 103 LYS A CA  1 
ATOM 2136 C C   . LYS C 3 103 ? 355.945 334.112 444.163 1.00 88.96  ? 103 LYS A C   1 
ATOM 2137 O O   . LYS C 3 103 ? 355.357 334.124 443.079 1.00 88.96  ? 103 LYS A O   1 
ATOM 2138 C CB  . LYS C 3 103 ? 358.147 335.178 443.747 1.00 88.96  ? 103 LYS A CB  1 
ATOM 2139 C CG  . LYS C 3 103 ? 359.086 336.332 443.978 1.00 88.96  ? 103 LYS A CG  1 
ATOM 2140 C CD  . LYS C 3 103 ? 360.507 335.950 443.635 1.00 88.96  ? 103 LYS A CD  1 
ATOM 2141 C CE  . LYS C 3 103 ? 360.624 335.518 442.195 1.00 88.96  ? 103 LYS A CE  1 
ATOM 2142 N NZ  . LYS C 3 103 ? 362.027 335.198 441.852 1.00 88.96  ? 103 LYS A NZ  1 
ATOM 2143 N N   . LEU C 3 104 ? 355.822 333.109 445.028 1.00 89.36  ? 104 LEU A N   1 
ATOM 2144 C CA  . LEU C 3 104 ? 355.007 331.950 444.706 1.00 89.36  ? 104 LEU A CA  1 
ATOM 2145 C C   . LEU C 3 104 ? 353.612 332.003 445.300 1.00 89.36  ? 104 LEU A C   1 
ATOM 2146 O O   . LEU C 3 104 ? 352.735 331.272 444.833 1.00 89.36  ? 104 LEU A O   1 
ATOM 2147 C CB  . LEU C 3 104 ? 355.694 330.665 445.168 1.00 89.36  ? 104 LEU A CB  1 
ATOM 2148 C CG  . LEU C 3 104 ? 356.745 330.099 444.218 1.00 89.36  ? 104 LEU A CG  1 
ATOM 2149 C CD1 . LEU C 3 104 ? 357.144 328.717 444.661 1.00 89.36  ? 104 LEU A CD1 1 
ATOM 2150 C CD2 . LEU C 3 104 ? 356.226 330.063 442.807 1.00 89.36  ? 104 LEU A CD2 1 
ATOM 2151 N N   . GLU C 3 105 ? 353.374 332.833 446.307 1.00 94.14  ? 105 GLU A N   1 
ATOM 2152 C CA  . GLU C 3 105 ? 352.020 333.030 446.798 1.00 94.14  ? 105 GLU A CA  1 
ATOM 2153 C C   . GLU C 3 105 ? 351.312 334.166 446.088 1.00 94.14  ? 105 GLU A C   1 
ATOM 2154 O O   . GLU C 3 105 ? 350.282 334.637 446.571 1.00 94.14  ? 105 GLU A O   1 
ATOM 2155 C CB  . GLU C 3 105 ? 352.014 333.279 448.308 1.00 94.14  ? 105 GLU A CB  1 
ATOM 2156 C CG  . GLU C 3 105 ? 352.832 332.291 449.125 1.00 94.14  ? 105 GLU A CG  1 
ATOM 2157 C CD  . GLU C 3 105 ? 352.519 330.844 448.814 1.00 94.14  ? 105 GLU A CD  1 
ATOM 2158 O OE1 . GLU C 3 105 ? 351.328 330.483 448.769 1.00 94.14  ? 105 GLU A OE1 1 
ATOM 2159 O OE2 . GLU C 3 105 ? 353.468 330.061 448.612 1.00 94.14  ? 105 GLU A OE2 1 
ATOM 2160 N N   . LEU C 3 106 ? 351.844 334.628 444.961 1.00 87.49  ? 106 LEU A N   1 
ATOM 2161 C CA  . LEU C 3 106 ? 351.080 335.546 444.136 1.00 87.49  ? 106 LEU A CA  1 
ATOM 2162 C C   . LEU C 3 106 ? 349.967 334.818 443.403 1.00 87.49  ? 106 LEU A C   1 
ATOM 2163 O O   . LEU C 3 106 ? 348.974 335.439 443.016 1.00 87.49  ? 106 LEU A O   1 
ATOM 2164 C CB  . LEU C 3 106 ? 351.994 336.257 443.144 1.00 87.49  ? 106 LEU A CB  1 
ATOM 2165 C CG  . LEU C 3 106 ? 352.574 337.588 443.611 1.00 87.49  ? 106 LEU A CG  1 
ATOM 2166 C CD1 . LEU C 3 106 ? 353.366 338.238 442.514 1.00 87.49  ? 106 LEU A CD1 1 
ATOM 2167 C CD2 . LEU C 3 106 ? 351.467 338.496 444.037 1.00 87.49  ? 106 LEU A CD2 1 
ATOM 2168 N N   . PHE C 3 107 ? 350.110 333.514 443.204 1.00 86.57  ? 107 PHE A N   1 
ATOM 2169 C CA  . PHE C 3 107 ? 349.093 332.707 442.557 1.00 86.57  ? 107 PHE A CA  1 
ATOM 2170 C C   . PHE C 3 107 ? 348.584 331.656 443.525 1.00 86.57  ? 107 PHE A C   1 
ATOM 2171 O O   . PHE C 3 107 ? 349.169 331.420 444.582 1.00 86.57  ? 107 PHE A O   1 
ATOM 2172 C CB  . PHE C 3 107 ? 349.637 332.041 441.303 1.00 86.57  ? 107 PHE A CB  1 
ATOM 2173 C CG  . PHE C 3 107 ? 350.525 332.923 440.515 1.00 86.57  ? 107 PHE A CG  1 
ATOM 2174 C CD1 . PHE C 3 107 ? 350.000 333.965 439.788 1.00 86.57  ? 107 PHE A CD1 1 
ATOM 2175 C CD2 . PHE C 3 107 ? 351.884 332.731 440.521 1.00 86.57  ? 107 PHE A CD2 1 
ATOM 2176 C CE1 . PHE C 3 107 ? 350.815 334.794 439.064 1.00 86.57  ? 107 PHE A CE1 1 
ATOM 2177 C CE2 . PHE C 3 107 ? 352.705 333.557 439.801 1.00 86.57  ? 107 PHE A CE2 1 
ATOM 2178 C CZ  . PHE C 3 107 ? 352.169 334.591 439.071 1.00 86.57  ? 107 PHE A CZ  1 
ATOM 2179 N N   . THR C 3 108 ? 347.483 331.019 443.148 1.00 86.66  ? 108 THR A N   1 
ATOM 2180 C CA  . THR C 3 108 ? 346.849 330.031 444.002 1.00 86.66  ? 108 THR A CA  1 
ATOM 2181 C C   . THR C 3 108 ? 347.205 328.604 443.610 1.00 86.66  ? 108 THR A C   1 
ATOM 2182 O O   . THR C 3 108 ? 347.704 327.845 444.442 1.00 86.66  ? 108 THR A O   1 
ATOM 2183 C CB  . THR C 3 108 ? 345.335 330.229 443.980 1.00 86.66  ? 108 THR A CB  1 
ATOM 2184 O OG1 . THR C 3 108 ? 345.022 331.483 444.589 1.00 86.66  ? 108 THR A OG1 1 
ATOM 2185 C CG2 . THR C 3 108 ? 344.647 329.127 444.743 1.00 86.66  ? 108 THR A CG2 1 
ATOM 2186 N N   . TYR C 3 109 ? 346.974 328.215 442.364 1.00 90.28  ? 109 TYR A N   1 
ATOM 2187 C CA  . TYR C 3 109 ? 347.279 326.867 441.915 1.00 90.28  ? 109 TYR A CA  1 
ATOM 2188 C C   . TYR C 3 109 ? 348.431 326.895 440.930 1.00 90.28  ? 109 TYR A C   1 
ATOM 2189 O O   . TYR C 3 109 ? 348.379 327.614 439.930 1.00 90.28  ? 109 TYR A O   1 
ATOM 2190 C CB  . TYR C 3 109 ? 346.066 326.217 441.268 1.00 90.28  ? 109 TYR A CB  1 
ATOM 2191 C CG  . TYR C 3 109 ? 344.871 326.211 442.159 1.00 90.28  ? 109 TYR A CG  1 
ATOM 2192 C CD1 . TYR C 3 109 ? 344.901 325.557 443.373 1.00 90.28  ? 109 TYR A CD1 1 
ATOM 2193 C CD2 . TYR C 3 109 ? 343.712 326.860 441.789 1.00 90.28  ? 109 TYR A CD2 1 
ATOM 2194 C CE1 . TYR C 3 109 ? 343.810 325.549 444.192 1.00 90.28  ? 109 TYR A CE1 1 
ATOM 2195 C CE2 . TYR C 3 109 ? 342.618 326.861 442.599 1.00 90.28  ? 109 TYR A CE2 1 
ATOM 2196 C CZ  . TYR C 3 109 ? 342.672 326.205 443.799 1.00 90.28  ? 109 TYR A CZ  1 
ATOM 2197 O OH  . TYR C 3 109 ? 341.569 326.205 444.612 1.00 90.28  ? 109 TYR A OH  1 
ATOM 2198 N N   . LEU C 3 110 ? 349.453 326.101 441.207 1.00 84.87  ? 110 LEU A N   1 
ATOM 2199 C CA  . LEU C 3 110 ? 350.608 325.967 440.342 1.00 84.87  ? 110 LEU A CA  1 
ATOM 2200 C C   . LEU C 3 110 ? 350.737 324.527 439.878 1.00 84.87  ? 110 LEU A C   1 
ATOM 2201 O O   . LEU C 3 110 ? 350.160 323.604 440.455 1.00 84.87  ? 110 LEU A O   1 
ATOM 2202 C CB  . LEU C 3 110 ? 351.884 326.391 441.063 1.00 84.87  ? 110 LEU A CB  1 
ATOM 2203 C CG  . LEU C 3 110 ? 351.939 327.852 441.466 1.00 84.87  ? 110 LEU A CG  1 
ATOM 2204 C CD1 . LEU C 3 110 ? 353.042 328.059 442.466 1.00 84.87  ? 110 LEU A CD1 1 
ATOM 2205 C CD2 . LEU C 3 110 ? 352.171 328.686 440.242 1.00 84.87  ? 110 LEU A CD2 1 
ATOM 2206 N N   . ARG C 3 111 ? 351.521 324.345 438.823 1.00 90.62  ? 111 ARG A N   1 
ATOM 2207 C CA  . ARG C 3 111 ? 351.836 323.011 438.330 1.00 90.62  ? 111 ARG A CA  1 
ATOM 2208 C C   . ARG C 3 111 ? 353.187 323.102 437.644 1.00 90.62  ? 111 ARG A C   1 
ATOM 2209 O O   . ARG C 3 111 ? 353.308 323.767 436.614 1.00 90.62  ? 111 ARG A O   1 
ATOM 2210 C CB  . ARG C 3 111 ? 350.769 322.515 437.373 1.00 90.62  ? 111 ARG A CB  1 
ATOM 2211 C CG  . ARG C 3 111 ? 350.972 321.083 436.948 1.00 90.62  ? 111 ARG A CG  1 
ATOM 2212 C CD  . ARG C 3 111 ? 350.455 320.840 435.557 1.00 90.62  ? 111 ARG A CD  1 
ATOM 2213 N NE  . ARG C 3 111 ? 350.378 319.416 435.276 1.00 90.62  ? 111 ARG A NE  1 
ATOM 2214 C CZ  . ARG C 3 111 ? 349.267 318.704 435.392 1.00 90.62  ? 111 ARG A CZ  1 
ATOM 2215 N NH1 . ARG C 3 111 ? 348.147 319.292 435.774 1.00 90.62  ? 111 ARG A NH1 1 
ATOM 2216 N NH2 . ARG C 3 111 ? 349.275 317.409 435.122 1.00 90.62  ? 111 ARG A NH2 1 
ATOM 2217 N N   . PHE C 3 112 ? 354.193 322.443 438.205 1.00 89.60  ? 112 PHE A N   1 
ATOM 2218 C CA  . PHE C 3 112 ? 355.530 322.563 437.659 1.00 89.60  ? 112 PHE A CA  1 
ATOM 2219 C C   . PHE C 3 112 ? 356.271 321.253 437.835 1.00 89.60  ? 112 PHE A C   1 
ATOM 2220 O O   . PHE C 3 112 ? 355.952 320.451 438.712 1.00 89.60  ? 112 PHE A O   1 
ATOM 2221 C CB  . PHE C 3 112 ? 356.309 323.696 438.327 1.00 89.60  ? 112 PHE A CB  1 
ATOM 2222 C CG  . PHE C 3 112 ? 356.226 323.701 439.827 1.00 89.60  ? 112 PHE A CG  1 
ATOM 2223 C CD1 . PHE C 3 112 ? 357.067 322.914 440.593 1.00 89.60  ? 112 PHE A CD1 1 
ATOM 2224 C CD2 . PHE C 3 112 ? 355.336 324.526 440.472 1.00 89.60  ? 112 PHE A CD2 1 
ATOM 2225 C CE1 . PHE C 3 112 ? 356.996 322.932 441.965 1.00 89.60  ? 112 PHE A CE1 1 
ATOM 2226 C CE2 . PHE C 3 112 ? 355.268 324.549 441.847 1.00 89.60  ? 112 PHE A CE2 1 
ATOM 2227 C CZ  . PHE C 3 112 ? 356.100 323.751 442.590 1.00 89.60  ? 112 PHE A CZ  1 
ATOM 2228 N N   . ASP C 3 113 ? 357.284 321.058 437.005 1.00 89.87  ? 113 ASP A N   1 
ATOM 2229 C CA  . ASP C 3 113 ? 358.234 319.993 437.249 1.00 89.87  ? 113 ASP A CA  1 
ATOM 2230 C C   . ASP C 3 113 ? 359.364 320.550 438.105 1.00 89.87  ? 113 ASP A C   1 
ATOM 2231 O O   . ASP C 3 113 ? 359.443 321.753 438.354 1.00 89.87  ? 113 ASP A O   1 
ATOM 2232 C CB  . ASP C 3 113 ? 358.732 319.422 435.930 1.00 89.87  ? 113 ASP A CB  1 
ATOM 2233 C CG  . ASP C 3 113 ? 357.724 318.492 435.291 1.00 89.87  ? 113 ASP A CG  1 
ATOM 2234 O OD1 . ASP C 3 113 ? 357.317 317.514 435.945 1.00 89.87  ? 113 ASP A OD1 1 
ATOM 2235 O OD2 . ASP C 3 113 ? 357.307 318.758 434.145 1.00 89.87  ? 113 ASP A OD2 1 
ATOM 2236 N N   . LEU C 3 114 ? 360.260 319.688 438.567 1.00 86.05  ? 114 LEU A N   1 
ATOM 2237 C CA  . LEU C 3 114 ? 361.238 320.134 439.542 1.00 86.05  ? 114 LEU A CA  1 
ATOM 2238 C C   . LEU C 3 114 ? 362.640 319.739 439.114 1.00 86.05  ? 114 LEU A C   1 
ATOM 2239 O O   . LEU C 3 114 ? 362.846 318.705 438.478 1.00 86.05  ? 114 LEU A O   1 
ATOM 2240 C CB  . LEU C 3 114 ? 360.937 319.566 440.922 1.00 86.05  ? 114 LEU A CB  1 
ATOM 2241 C CG  . LEU C 3 114 ? 361.349 320.498 442.052 1.00 86.05  ? 114 LEU A CG  1 
ATOM 2242 C CD1 . LEU C 3 114 ? 360.695 321.834 441.843 1.00 86.05  ? 114 LEU A CD1 1 
ATOM 2243 C CD2 . LEU C 3 114 ? 360.944 319.921 443.381 1.00 86.05  ? 114 LEU A CD2 1 
ATOM 2244 N N   . GLU C 3 115 ? 363.603 320.580 439.475 1.00 90.29  ? 115 GLU A N   1 
ATOM 2245 C CA  . GLU C 3 115 ? 365.007 320.365 439.152 1.00 90.29  ? 115 GLU A CA  1 
ATOM 2246 C C   . GLU C 3 115 ? 365.833 320.601 440.396 1.00 90.29  ? 115 GLU A C   1 
ATOM 2247 O O   . GLU C 3 115 ? 365.721 321.656 441.022 1.00 90.29  ? 115 GLU A O   1 
ATOM 2248 C CB  . GLU C 3 115 ? 365.467 321.291 438.029 1.00 90.29  ? 115 GLU A CB  1 
ATOM 2249 C CG  . GLU C 3 115 ? 364.851 321.002 436.676 1.00 90.29  ? 115 GLU A CG  1 
ATOM 2250 C CD  . GLU C 3 115 ? 365.415 319.757 436.005 1.00 90.29  ? 115 GLU A CD  1 
ATOM 2251 O OE1 . GLU C 3 115 ? 366.345 319.127 436.545 1.00 90.29  ? 115 GLU A OE1 1 
ATOM 2252 O OE2 . GLU C 3 115 ? 364.912 319.390 434.926 1.00 90.29  ? 115 GLU A OE2 1 
ATOM 2253 N N   . LEU C 3 116 ? 366.658 319.632 440.748 1.00 81.21  ? 116 LEU A N   1 
ATOM 2254 C CA  . LEU C 3 116 ? 367.434 319.678 441.972 1.00 81.21  ? 116 LEU A CA  1 
ATOM 2255 C C   . LEU C 3 116 ? 368.909 319.538 441.647 1.00 81.21  ? 116 LEU A C   1 
ATOM 2256 O O   . LEU C 3 116 ? 369.289 318.743 440.789 1.00 81.21  ? 116 LEU A O   1 
ATOM 2257 C CB  . LEU C 3 116 ? 367.001 318.579 442.919 1.00 81.21  ? 116 LEU A CB  1 
ATOM 2258 C CG  . LEU C 3 116 ? 366.052 318.982 444.035 1.00 81.21  ? 116 LEU A CG  1 
ATOM 2259 C CD1 . LEU C 3 116 ? 364.736 319.456 443.510 1.00 81.21  ? 116 LEU A CD1 1 
ATOM 2260 C CD2 . LEU C 3 116 ? 365.833 317.786 444.896 1.00 81.21  ? 116 LEU A CD2 1 
ATOM 2261 N N   . THR C 3 117 ? 369.736 320.314 442.336 1.00 83.53  ? 117 THR A N   1 
ATOM 2262 C CA  . THR C 3 117 ? 371.177 320.270 442.154 1.00 83.53  ? 117 THR A CA  1 
ATOM 2263 C C   . THR C 3 117 ? 371.827 320.521 443.499 1.00 83.53  ? 117 THR A C   1 
ATOM 2264 O O   . THR C 3 117 ? 371.449 321.459 444.200 1.00 83.53  ? 117 THR A O   1 
ATOM 2265 C CB  . THR C 3 117 ? 371.634 321.314 441.138 1.00 83.53  ? 117 THR A CB  1 
ATOM 2266 O OG1 . THR C 3 117 ? 370.954 321.098 439.898 1.00 83.53  ? 117 THR A OG1 1 
ATOM 2267 C CG2 . THR C 3 117 ? 373.111 321.200 440.899 1.00 83.53  ? 117 THR A CG2 1 
ATOM 2268 N N   . PHE C 3 118 ? 372.784 319.683 443.866 1.00 79.67  ? 118 PHE A N   1 
ATOM 2269 C CA  . PHE C 3 118 ? 373.435 319.757 445.162 1.00 79.67  ? 118 PHE A CA  1 
ATOM 2270 C C   . PHE C 3 118 ? 374.905 320.073 444.963 1.00 79.67  ? 118 PHE A C   1 
ATOM 2271 O O   . PHE C 3 118 ? 375.543 319.506 444.077 1.00 79.67  ? 118 PHE A O   1 
ATOM 2272 C CB  . PHE C 3 118 ? 373.295 318.442 445.922 1.00 79.67  ? 118 PHE A CB  1 
ATOM 2273 C CG  . PHE C 3 118 ? 371.965 317.779 445.762 1.00 79.67  ? 118 PHE A CG  1 
ATOM 2274 C CD1 . PHE C 3 118 ? 370.926 318.090 446.606 1.00 79.67  ? 118 PHE A CD1 1 
ATOM 2275 C CD2 . PHE C 3 118 ? 371.765 316.812 444.797 1.00 79.67  ? 118 PHE A CD2 1 
ATOM 2276 C CE1 . PHE C 3 118 ? 369.712 317.472 446.474 1.00 79.67  ? 118 PHE A CE1 1 
ATOM 2277 C CE2 . PHE C 3 118 ? 370.553 316.197 444.662 1.00 79.67  ? 118 PHE A CE2 1 
ATOM 2278 C CZ  . PHE C 3 118 ? 369.528 316.524 445.500 1.00 79.67  ? 118 PHE A CZ  1 
ATOM 2279 N N   . VAL C 3 119 ? 375.445 320.965 445.785 1.00 78.37  ? 119 VAL A N   1 
ATOM 2280 C CA  . VAL C 3 119 ? 376.872 321.254 445.728 1.00 78.37  ? 119 VAL A CA  1 
ATOM 2281 C C   . VAL C 3 119 ? 377.558 320.791 447.005 1.00 78.37  ? 119 VAL A C   1 
ATOM 2282 O O   . VAL C 3 119 ? 377.693 321.536 447.978 1.00 78.37  ? 119 VAL A O   1 
ATOM 2283 C CB  . VAL C 3 119 ? 377.117 322.741 445.437 1.00 78.37  ? 119 VAL A CB  1 
ATOM 2284 C CG1 . VAL C 3 119 ? 376.947 322.984 443.976 1.00 78.37  ? 119 VAL A CG1 1 
ATOM 2285 C CG2 . VAL C 3 119 ? 376.086 323.589 446.144 1.00 78.37  ? 119 VAL A CG2 1 
ATOM 2286 N N   . ILE C 3 120 ? 378.039 319.560 446.985 1.00 82.09  ? 120 ILE A N   1 
ATOM 2287 C CA  . ILE C 3 120 ? 378.579 318.898 448.161 1.00 82.09  ? 120 ILE A CA  1 
ATOM 2288 C C   . ILE C 3 120 ? 380.052 319.241 448.295 1.00 82.09  ? 120 ILE A C   1 
ATOM 2289 O O   . ILE C 3 120 ? 380.832 319.028 447.362 1.00 82.09  ? 120 ILE A O   1 
ATOM 2290 C CB  . ILE C 3 120 ? 378.382 317.381 448.062 1.00 82.09  ? 120 ILE A CB  1 
ATOM 2291 C CG1 . ILE C 3 120 ? 376.897 317.063 447.945 1.00 82.09  ? 120 ILE A CG1 1 
ATOM 2292 C CG2 . ILE C 3 120 ? 378.998 316.693 449.249 1.00 82.09  ? 120 ILE A CG2 1 
ATOM 2293 C CD1 . ILE C 3 120 ? 376.607 315.599 447.868 1.00 82.09  ? 120 ILE A CD1 1 
ATOM 2294 N N   . THR C 3 121 ? 380.438 319.764 449.450 1.00 84.54  ? 121 THR A N   1 
ATOM 2295 C CA  . THR C 3 121 ? 381.838 319.979 449.764 1.00 84.54  ? 121 THR A CA  1 
ATOM 2296 C C   . THR C 3 121 ? 382.141 319.404 451.135 1.00 84.54  ? 121 THR A C   1 
ATOM 2297 O O   . THR C 3 121 ? 381.242 319.162 451.942 1.00 84.54  ? 121 THR A O   1 
ATOM 2298 C CB  . THR C 3 121 ? 382.213 321.455 449.726 1.00 84.54  ? 121 THR A CB  1 
ATOM 2299 O OG1 . THR C 3 121 ? 383.609 321.594 450.014 1.00 84.54  ? 121 THR A OG1 1 
ATOM 2300 C CG2 . THR C 3 121 ? 381.407 322.232 450.735 1.00 84.54  ? 121 THR A CG2 1 
ATOM 2301 N N   . SER C 3 122 ? 383.424 319.185 451.393 1.00 86.53  ? 122 SER A N   1 
ATOM 2302 C CA  . SER C 3 122 ? 383.861 318.505 452.599 1.00 86.53  ? 122 SER A CA  1 
ATOM 2303 C C   . SER C 3 122 ? 384.820 319.391 453.372 1.00 86.53  ? 122 SER A C   1 
ATOM 2304 O O   . SER C 3 122 ? 385.237 320.451 452.906 1.00 86.53  ? 122 SER A O   1 
ATOM 2305 C CB  . SER C 3 122 ? 384.532 317.171 452.271 1.00 86.53  ? 122 SER A CB  1 
ATOM 2306 O OG  . SER C 3 122 ? 383.785 316.463 451.302 1.00 86.53  ? 122 SER A OG  1 
ATOM 2307 N N   . ALA C 3 123 ? 385.173 318.928 454.565 1.00 93.67  ? 123 ALA A N   1 
ATOM 2308 C CA  . ALA C 3 123 ? 386.096 319.636 455.438 1.00 93.67  ? 123 ALA A CA  1 
ATOM 2309 C C   . ALA C 3 123 ? 386.660 318.640 456.433 1.00 93.67  ? 123 ALA A C   1 
ATOM 2310 O O   . ALA C 3 123 ? 385.945 317.738 456.875 1.00 93.67  ? 123 ALA A O   1 
ATOM 2311 C CB  . ALA C 3 123 ? 385.399 320.780 456.173 1.00 93.67  ? 123 ALA A CB  1 
ATOM 2312 N N   . GLN C 3 124 ? 387.929 318.799 456.782 1.00 103.59 ? 124 GLN A N   1 
ATOM 2313 C CA  . GLN C 3 124 ? 388.575 317.866 457.691 1.00 103.59 ? 124 GLN A CA  1 
ATOM 2314 C C   . GLN C 3 124 ? 388.349 318.287 459.135 1.00 103.59 ? 124 GLN A C   1 
ATOM 2315 O O   . GLN C 3 124 ? 388.628 319.428 459.508 1.00 103.59 ? 124 GLN A O   1 
ATOM 2316 C CB  . GLN C 3 124 ? 390.068 317.782 457.393 1.00 103.59 ? 124 GLN A CB  1 
ATOM 2317 C CG  . GLN C 3 124 ? 390.847 316.984 458.411 1.00 103.59 ? 124 GLN A CG  1 
ATOM 2318 C CD  . GLN C 3 124 ? 392.207 316.572 457.906 1.00 103.59 ? 124 GLN A CD  1 
ATOM 2319 O OE1 . GLN C 3 124 ? 392.543 316.797 456.745 1.00 103.59 ? 124 GLN A OE1 1 
ATOM 2320 N NE2 . GLN C 3 124 ? 393.001 315.961 458.775 1.00 103.59 ? 124 GLN A NE2 1 
ATOM 2321 N N   . GLN C 3 125 ? 387.840 317.372 459.940 1.00 106.02 ? 125 GLN A N   1 
ATOM 2322 C CA  . GLN C 3 125 ? 387.723 317.598 461.366 1.00 106.02 ? 125 GLN A CA  1 
ATOM 2323 C C   . GLN C 3 125 ? 389.060 317.333 462.043 1.00 106.02 ? 125 GLN A C   1 
ATOM 2324 O O   . GLN C 3 125 ? 389.875 316.565 461.531 1.00 106.02 ? 125 GLN A O   1 
ATOM 2325 C CB  . GLN C 3 125 ? 386.643 316.694 461.942 1.00 106.02 ? 125 GLN A CB  1 
ATOM 2326 C CG  . GLN C 3 125 ? 385.273 317.304 461.876 1.00 106.02 ? 125 GLN A CG  1 
ATOM 2327 C CD  . GLN C 3 125 ? 385.222 318.654 462.546 1.00 106.02 ? 125 GLN A CD  1 
ATOM 2328 O OE1 . GLN C 3 125 ? 385.193 319.690 461.884 1.00 106.02 ? 125 GLN A OE1 1 
ATOM 2329 N NE2 . GLN C 3 125 ? 385.208 318.653 463.872 1.00 106.02 ? 125 GLN A NE2 1 
ATOM 2330 N N   . PRO C 3 126 ? 389.328 317.976 463.194 1.00 112.03 ? 126 PRO A N   1 
ATOM 2331 C CA  . PRO C 3 126 ? 390.622 317.766 463.858 1.00 112.03 ? 126 PRO A CA  1 
ATOM 2332 C C   . PRO C 3 126 ? 390.774 316.373 464.441 1.00 112.03 ? 126 PRO A C   1 
ATOM 2333 O O   . PRO C 3 126 ? 390.161 316.034 465.456 1.00 112.03 ? 126 PRO A O   1 
ATOM 2334 C CB  . PRO C 3 126 ? 390.632 318.832 464.960 1.00 112.03 ? 126 PRO A CB  1 
ATOM 2335 C CG  . PRO C 3 126 ? 389.212 319.194 465.157 1.00 112.03 ? 126 PRO A CG  1 
ATOM 2336 C CD  . PRO C 3 126 ? 388.586 319.087 463.811 1.00 112.03 ? 126 PRO A CD  1 
ATOM 2337 N N   . SER C 3 127 ? 391.609 315.566 463.795 1.00 126.72 ? 127 SER A N   1 
ATOM 2338 C CA  . SER C 3 127 ? 391.876 314.205 464.236 1.00 126.72 ? 127 SER A CA  1 
ATOM 2339 C C   . SER C 3 127 ? 392.971 314.228 465.296 1.00 126.72 ? 127 SER A C   1 
ATOM 2340 O O   . SER C 3 127 ? 393.372 315.285 465.789 1.00 126.72 ? 127 SER A O   1 
ATOM 2341 C CB  . SER C 3 127 ? 392.270 313.328 463.055 1.00 126.72 ? 127 SER A CB  1 
ATOM 2342 O OG  . SER C 3 127 ? 393.672 313.376 462.852 1.00 126.72 ? 127 SER A OG  1 
ATOM 2343 N N   . THR C 3 128 ? 393.477 313.052 465.661 1.00 134.27 ? 128 THR A N   1 
ATOM 2344 C CA  . THR C 3 128 ? 394.506 313.010 466.695 1.00 134.27 ? 128 THR A CA  1 
ATOM 2345 C C   . THR C 3 128 ? 395.889 313.287 466.115 1.00 134.27 ? 128 THR A C   1 
ATOM 2346 O O   . THR C 3 128 ? 396.458 314.360 466.341 1.00 134.27 ? 128 THR A O   1 
ATOM 2347 C CB  . THR C 3 128 ? 394.481 311.653 467.400 1.00 134.27 ? 128 THR A CB  1 
ATOM 2348 O OG1 . THR C 3 128 ? 394.414 310.611 466.419 1.00 134.27 ? 128 THR A OG1 1 
ATOM 2349 C CG2 . THR C 3 128 ? 393.278 311.557 468.318 1.00 134.27 ? 128 THR A CG2 1 
ATOM 2350 N N   . ALA C 3 129 ? 396.406 312.361 465.310 1.00 134.08 ? 129 ALA A N   1 
ATOM 2351 C CA  . ALA C 3 129 ? 397.808 312.370 464.888 1.00 134.08 ? 129 ALA A CA  1 
ATOM 2352 C C   . ALA C 3 129 ? 398.020 311.285 463.838 1.00 134.08 ? 129 ALA A C   1 
ATOM 2353 O O   . ALA C 3 129 ? 397.065 310.690 463.324 1.00 134.08 ? 129 ALA A O   1 
ATOM 2354 C CB  . ALA C 3 129 ? 398.762 312.155 466.067 1.00 134.08 ? 129 ALA A CB  1 
ATOM 2355 N N   . SER C 3 130 ? 399.299 311.030 463.544 1.00 135.56 ? 130 SER A N   1 
ATOM 2356 C CA  . SER C 3 130 ? 399.825 309.839 462.860 1.00 135.56 ? 130 SER A CA  1 
ATOM 2357 C C   . SER C 3 130 ? 399.346 309.728 461.412 1.00 135.56 ? 130 SER A C   1 
ATOM 2358 O O   . SER C 3 130 ? 398.748 308.728 461.007 1.00 135.56 ? 130 SER A O   1 
ATOM 2359 C CB  . SER C 3 130 ? 399.524 308.540 463.632 1.00 135.56 ? 130 SER A CB  1 
ATOM 2360 O OG  . SER C 3 130 ? 398.151 308.316 463.912 1.00 135.56 ? 130 SER A OG  1 
ATOM 2361 N N   . SER C 3 131 ? 399.639 310.782 460.642 1.00 135.05 ? 131 SER A N   1 
ATOM 2362 C CA  . SER C 3 131 ? 399.704 310.765 459.175 1.00 135.05 ? 131 SER A CA  1 
ATOM 2363 C C   . SER C 3 131 ? 398.366 310.368 458.543 1.00 135.05 ? 131 SER A C   1 
ATOM 2364 O O   . SER C 3 131 ? 398.222 309.313 457.925 1.00 135.05 ? 131 SER A O   1 
ATOM 2365 C CB  . SER C 3 131 ? 400.828 309.837 458.698 1.00 135.05 ? 131 SER A CB  1 
ATOM 2366 O OG  . SER C 3 131 ? 400.614 309.420 457.361 1.00 135.05 ? 131 SER A OG  1 
ATOM 2367 N N   . VAL C 3 132 ? 397.383 311.244 458.734 1.00 125.94 ? 132 VAL A N   1 
ATOM 2368 C CA  . VAL C 3 132 ? 396.045 310.974 458.229 1.00 125.94 ? 132 VAL A CA  1 
ATOM 2369 C C   . VAL C 3 132 ? 396.030 311.128 456.712 1.00 125.94 ? 132 VAL A C   1 
ATOM 2370 O O   . VAL C 3 132 ? 396.591 312.080 456.156 1.00 125.94 ? 132 VAL A O   1 
ATOM 2371 C CB  . VAL C 3 132 ? 395.022 311.883 458.930 1.00 125.94 ? 132 VAL A CB  1 
ATOM 2372 C CG1 . VAL C 3 132 ? 395.447 313.350 458.891 1.00 125.94 ? 132 VAL A CG1 1 
ATOM 2373 C CG2 . VAL C 3 132 ? 393.632 311.698 458.348 1.00 125.94 ? 132 VAL A CG2 1 
ATOM 2374 N N   . ASP C 3 133 ? 395.439 310.152 456.031 1.00 126.89 ? 133 ASP A N   1 
ATOM 2375 C CA  . ASP C 3 133 ? 395.306 310.175 454.583 1.00 126.89 ? 133 ASP A CA  1 
ATOM 2376 C C   . ASP C 3 133 ? 394.066 309.376 454.224 1.00 126.89 ? 133 ASP A C   1 
ATOM 2377 O O   . ASP C 3 133 ? 393.821 308.311 454.796 1.00 126.89 ? 133 ASP A O   1 
ATOM 2378 C CB  . ASP C 3 133 ? 396.542 309.582 453.896 1.00 126.89 ? 133 ASP A CB  1 
ATOM 2379 C CG  . ASP C 3 133 ? 396.443 309.590 452.372 1.00 126.89 ? 133 ASP A CG  1 
ATOM 2380 O OD1 . ASP C 3 133 ? 395.584 310.298 451.799 1.00 126.89 ? 133 ASP A OD1 1 
ATOM 2381 O OD2 . ASP C 3 133 ? 397.238 308.865 451.738 1.00 126.89 ? 133 ASP A OD2 1 
ATOM 2382 N N   . ALA C 3 134 ? 393.304 309.882 453.263 1.00 114.23 ? 134 ALA A N   1 
ATOM 2383 C CA  . ALA C 3 134 ? 392.029 309.288 452.913 1.00 114.23 ? 134 ALA A CA  1 
ATOM 2384 C C   . ALA C 3 134 ? 391.865 309.248 451.404 1.00 114.23 ? 134 ALA A C   1 
ATOM 2385 O O   . ALA C 3 134 ? 392.432 310.078 450.689 1.00 114.23 ? 134 ALA A O   1 
ATOM 2386 C CB  . ALA C 3 134 ? 390.867 310.080 453.531 1.00 114.23 ? 134 ALA A CB  1 
ATOM 2387 N N   . PRO C 3 135 ? 391.098 308.290 450.894 1.00 105.52 ? 135 PRO A N   1 
ATOM 2388 C CA  . PRO C 3 135 ? 390.701 308.340 449.485 1.00 105.52 ? 135 PRO A CA  1 
ATOM 2389 C C   . PRO C 3 135 ? 389.537 309.291 449.282 1.00 105.52 ? 135 PRO A C   1 
ATOM 2390 O O   . PRO C 3 135 ? 389.144 309.998 450.214 1.00 105.52 ? 135 PRO A O   1 
ATOM 2391 C CB  . PRO C 3 135 ? 390.308 306.891 449.175 1.00 105.52 ? 135 PRO A CB  1 
ATOM 2392 C CG  . PRO C 3 135 ? 390.802 306.087 450.338 1.00 105.52 ? 135 PRO A CG  1 
ATOM 2393 C CD  . PRO C 3 135 ? 390.741 307.003 451.502 1.00 105.52 ? 135 PRO A CD  1 
ATOM 2394 N N   . VAL C 3 136 ? 388.980 309.321 448.072 1.00 99.02  ? 136 VAL A N   1 
ATOM 2395 C CA  . VAL C 3 136 ? 387.899 310.248 447.772 1.00 99.02  ? 136 VAL A CA  1 
ATOM 2396 C C   . VAL C 3 136 ? 386.632 309.825 448.497 1.00 99.02  ? 136 VAL A C   1 
ATOM 2397 O O   . VAL C 3 136 ? 386.450 308.651 448.842 1.00 99.02  ? 136 VAL A O   1 
ATOM 2398 C CB  . VAL C 3 136 ? 387.667 310.323 446.258 1.00 99.02  ? 136 VAL A CB  1 
ATOM 2399 C CG1 . VAL C 3 136 ? 388.850 310.979 445.590 1.00 99.02  ? 136 VAL A CG1 1 
ATOM 2400 C CG2 . VAL C 3 136 ? 387.438 308.934 445.700 1.00 99.02  ? 136 VAL A CG2 1 
ATOM 2401 N N   . GLN C 3 137 ? 385.757 310.787 448.747 1.00 96.46  ? 137 GLN A N   1 
ATOM 2402 C CA  . GLN C 3 137 ? 384.516 310.509 449.441 1.00 96.46  ? 137 GLN A CA  1 
ATOM 2403 C C   . GLN C 3 137 ? 383.378 310.313 448.452 1.00 96.46  ? 137 GLN A C   1 
ATOM 2404 O O   . GLN C 3 137 ? 383.380 310.846 447.342 1.00 96.46  ? 137 GLN A O   1 
ATOM 2405 C CB  . GLN C 3 137 ? 384.197 311.631 450.416 1.00 96.46  ? 137 GLN A CB  1 
ATOM 2406 C CG  . GLN C 3 137 ? 385.243 311.773 451.477 1.00 96.46  ? 137 GLN A CG  1 
ATOM 2407 C CD  . GLN C 3 137 ? 385.623 310.439 452.063 1.00 96.46  ? 137 GLN A CD  1 
ATOM 2408 O OE1 . GLN C 3 137 ? 386.748 309.976 451.899 1.00 96.46  ? 137 GLN A OE1 1 
ATOM 2409 N NE2 . GLN C 3 137 ? 384.684 309.808 452.754 1.00 96.46  ? 137 GLN A NE2 1 
ATOM 2410 N N   . THR C 3 138 ? 382.389 309.536 448.874 1.00 89.93  ? 138 THR A N   1 
ATOM 2411 C CA  . THR C 3 138 ? 381.257 309.193 448.029 1.00 89.93  ? 138 THR A CA  1 
ATOM 2412 C C   . THR C 3 138 ? 379.983 309.432 448.815 1.00 89.93  ? 138 THR A C   1 
ATOM 2413 O O   . THR C 3 138 ? 379.750 308.780 449.834 1.00 89.93  ? 138 THR A O   1 
ATOM 2414 C CB  . THR C 3 138 ? 381.332 307.735 447.581 1.00 89.93  ? 138 THR A CB  1 
ATOM 2415 O OG1 . THR C 3 138 ? 382.513 307.535 446.802 1.00 89.93  ? 138 THR A OG1 1 
ATOM 2416 C CG2 . THR C 3 138 ? 380.125 307.373 446.755 1.00 89.93  ? 138 THR A CG2 1 
ATOM 2417 N N   . HIS C 3 139 ? 379.165 310.358 448.347 1.00 80.45  ? 139 HIS A N   1 
ATOM 2418 C CA  . HIS C 3 139 ? 377.956 310.731 449.052 1.00 80.45  ? 139 HIS A CA  1 
ATOM 2419 C C   . HIS C 3 139 ? 376.759 310.103 448.362 1.00 80.45  ? 139 HIS A C   1 
ATOM 2420 O O   . HIS C 3 139 ? 376.674 310.087 447.134 1.00 80.45  ? 139 HIS A O   1 
ATOM 2421 C CB  . HIS C 3 139 ? 377.801 312.244 449.102 1.00 80.45  ? 139 HIS A CB  1 
ATOM 2422 C CG  . HIS C 3 139 ? 378.919 312.940 449.809 1.00 80.45  ? 139 HIS A CG  1 
ATOM 2423 N ND1 . HIS C 3 139 ? 378.760 313.539 451.038 1.00 80.45  ? 139 HIS A ND1 1 
ATOM 2424 C CD2 . HIS C 3 139 ? 380.210 313.138 449.459 1.00 80.45  ? 139 HIS A CD2 1 
ATOM 2425 C CE1 . HIS C 3 139 ? 379.907 314.067 451.420 1.00 80.45  ? 139 HIS A CE1 1 
ATOM 2426 N NE2 . HIS C 3 139 ? 380.802 313.842 450.477 1.00 80.45  ? 139 HIS A NE2 1 
ATOM 2427 N N   . GLN C 3 140 ? 375.839 309.573 449.159 1.00 75.21  ? 140 GLN A N   1 
ATOM 2428 C CA  . GLN C 3 140 ? 374.621 308.961 448.649 1.00 75.21  ? 140 GLN A CA  1 
ATOM 2429 C C   . GLN C 3 140 ? 373.451 309.854 449.006 1.00 75.21  ? 140 GLN A C   1 
ATOM 2430 O O   . GLN C 3 140 ? 373.248 310.164 450.181 1.00 75.21  ? 140 GLN A O   1 
ATOM 2431 C CB  . GLN C 3 140 ? 374.406 307.568 449.228 1.00 75.21  ? 140 GLN A CB  1 
ATOM 2432 C CG  . GLN C 3 140 ? 373.074 306.983 448.846 1.00 75.21  ? 140 GLN A CG  1 
ATOM 2433 C CD  . GLN C 3 140 ? 372.602 305.941 449.813 1.00 75.21  ? 140 GLN A CD  1 
ATOM 2434 O OE1 . GLN C 3 140 ? 373.248 305.675 450.820 1.00 75.21  ? 140 GLN A OE1 1 
ATOM 2435 N NE2 . GLN C 3 140 ? 371.463 305.342 449.518 1.00 75.21  ? 140 GLN A NE2 1 
ATOM 2436 N N   . ILE C 3 141 ? 372.681 310.251 448.008 1.00 77.58  ? 141 ILE A N   1 
ATOM 2437 C CA  . ILE C 3 141 ? 371.582 311.191 448.189 1.00 77.58  ? 141 ILE A CA  1 
ATOM 2438 C C   . ILE C 3 141 ? 370.297 310.442 447.870 1.00 77.58  ? 141 ILE A C   1 
ATOM 2439 O O   . ILE C 3 141 ? 369.926 310.275 446.708 1.00 77.58  ? 141 ILE A O   1 
ATOM 2440 C CB  . ILE C 3 141 ? 371.737 312.428 447.313 1.00 77.58  ? 141 ILE A CB  1 
ATOM 2441 C CG1 . ILE C 3 141 ? 373.097 313.059 447.560 1.00 77.58  ? 141 ILE A CG1 1 
ATOM 2442 C CG2 . ILE C 3 141 ? 370.644 313.410 447.604 1.00 77.58  ? 141 ILE A CG2 1 
ATOM 2443 C CD1 . ILE C 3 141 ? 373.422 314.150 446.606 1.00 77.58  ? 141 ILE A CD1 1 
ATOM 2444 N N   . MET C 3 142 ? 369.601 309.990 448.902 1.00 83.42  ? 142 MET A N   1 
ATOM 2445 C CA  . MET C 3 142 ? 368.384 309.224 448.705 1.00 83.42  ? 142 MET A CA  1 
ATOM 2446 C C   . MET C 3 142 ? 367.191 310.149 448.570 1.00 83.42  ? 142 MET A C   1 
ATOM 2447 O O   . MET C 3 142 ? 367.176 311.257 449.106 1.00 83.42  ? 142 MET A O   1 
ATOM 2448 C CB  . MET C 3 142 ? 368.146 308.252 449.859 1.00 83.42  ? 142 MET A CB  1 
ATOM 2449 C CG  . MET C 3 142 ? 367.395 307.007 449.441 1.00 83.42  ? 142 MET A CG  1 
ATOM 2450 S SD  . MET C 3 142 ? 367.187 305.807 450.756 1.00 83.42  ? 142 MET A SD  1 
ATOM 2451 C CE  . MET C 3 142 ? 365.972 306.632 451.762 1.00 83.42  ? 142 MET A CE  1 
ATOM 2452 N N   . TYR C 3 143 ? 366.188 309.681 447.843 1.00 82.64  ? 143 TYR A N   1 
ATOM 2453 C CA  . TYR C 3 143 ? 364.931 310.390 447.679 1.00 82.64  ? 143 TYR A CA  1 
ATOM 2454 C C   . TYR C 3 143 ? 363.813 309.451 448.090 1.00 82.64  ? 143 TYR A C   1 
ATOM 2455 O O   . TYR C 3 143 ? 363.882 308.251 447.816 1.00 82.64  ? 143 TYR A O   1 
ATOM 2456 C CB  . TYR C 3 143 ? 364.752 310.847 446.238 1.00 82.64  ? 143 TYR A CB  1 
ATOM 2457 C CG  . TYR C 3 143 ? 363.354 311.276 445.911 1.00 82.64  ? 143 TYR A CG  1 
ATOM 2458 C CD1 . TYR C 3 143 ? 362.810 312.407 446.484 1.00 82.64  ? 143 TYR A CD1 1 
ATOM 2459 C CD2 . TYR C 3 143 ? 362.581 310.552 445.027 1.00 82.64  ? 143 TYR A CD2 1 
ATOM 2460 C CE1 . TYR C 3 143 ? 361.538 312.806 446.187 1.00 82.64  ? 143 TYR A CE1 1 
ATOM 2461 C CE2 . TYR C 3 143 ? 361.307 310.945 444.724 1.00 82.64  ? 143 TYR A CE2 1 
ATOM 2462 C CZ  . TYR C 3 143 ? 360.795 312.072 445.305 1.00 82.64  ? 143 TYR A CZ  1 
ATOM 2463 O OH  . TYR C 3 143 ? 359.522 312.465 445.004 1.00 82.64  ? 143 TYR A OH  1 
ATOM 2464 N N   . VAL C 3 144 ? 362.799 309.984 448.757 1.00 84.20  ? 144 VAL A N   1 
ATOM 2465 C CA  . VAL C 3 144 ? 361.656 309.199 449.211 1.00 84.20  ? 144 VAL A CA  1 
ATOM 2466 C C   . VAL C 3 144 ? 360.398 309.797 448.594 1.00 84.20  ? 144 VAL A C   1 
ATOM 2467 O O   . VAL C 3 144 ? 360.112 310.976 448.834 1.00 84.20  ? 144 VAL A O   1 
ATOM 2468 C CB  . VAL C 3 144 ? 361.557 309.183 450.738 1.00 84.20  ? 144 VAL A CB  1 
ATOM 2469 C CG1 . VAL C 3 144 ? 360.300 308.491 451.163 1.00 84.20  ? 144 VAL A CG1 1 
ATOM 2470 C CG2 . VAL C 3 144 ? 362.743 308.479 451.317 1.00 84.20  ? 144 VAL A CG2 1 
ATOM 2471 N N   . PRO C 3 145 ? 359.637 309.044 447.810 1.00 83.77  ? 145 PRO A N   1 
ATOM 2472 C CA  . PRO C 3 145 ? 358.376 309.550 447.288 1.00 83.77  ? 145 PRO A CA  1 
ATOM 2473 C C   . PRO C 3 145 ? 357.352 309.647 448.401 1.00 83.77  ? 145 PRO A C   1 
ATOM 2474 O O   . PRO C 3 145 ? 357.543 309.043 449.466 1.00 83.77  ? 145 PRO A O   1 
ATOM 2475 C CB  . PRO C 3 145 ? 357.979 308.488 446.248 1.00 83.77  ? 145 PRO A CB  1 
ATOM 2476 C CG  . PRO C 3 145 ? 359.204 307.718 445.991 1.00 83.77  ? 145 PRO A CG  1 
ATOM 2477 C CD  . PRO C 3 145 ? 359.936 307.711 447.282 1.00 83.77  ? 145 PRO A CD  1 
ATOM 2478 N N   . PRO C 3 146 ? 356.271 310.415 448.215 1.00 91.26  ? 146 PRO A N   1 
ATOM 2479 C CA  . PRO C 3 146 ? 355.255 310.513 449.269 1.00 91.26  ? 146 PRO A CA  1 
ATOM 2480 C C   . PRO C 3 146 ? 354.554 309.194 449.527 1.00 91.26  ? 146 PRO A C   1 
ATOM 2481 O O   . PRO C 3 146 ? 353.936 308.620 448.628 1.00 91.26  ? 146 PRO A O   1 
ATOM 2482 C CB  . PRO C 3 146 ? 354.282 311.561 448.720 1.00 91.26  ? 146 PRO A CB  1 
ATOM 2483 C CG  . PRO C 3 146 ? 354.517 311.560 447.254 1.00 91.26  ? 146 PRO A CG  1 
ATOM 2484 C CD  . PRO C 3 146 ? 355.976 311.338 447.109 1.00 91.26  ? 146 PRO A CD  1 
ATOM 2485 N N   . GLY C 3 147 ? 354.664 308.699 450.752 1.00 95.97  ? 147 GLY A N   1 
ATOM 2486 C CA  . GLY C 3 147 ? 354.129 307.395 451.068 1.00 95.97  ? 147 GLY A CA  1 
ATOM 2487 C C   . GLY C 3 147 ? 355.160 306.300 450.908 1.00 95.97  ? 147 GLY A C   1 
ATOM 2488 O O   . GLY C 3 147 ? 354.933 305.323 450.194 1.00 95.97  ? 147 GLY A O   1 
ATOM 2489 N N   . GLY C 3 148 ? 356.305 306.462 451.556 1.00 92.25  ? 148 GLY A N   1 
ATOM 2490 C CA  . GLY C 3 148 ? 357.325 305.447 451.541 1.00 92.25  ? 148 GLY A CA  1 
ATOM 2491 C C   . GLY C 3 148 ? 357.908 305.233 452.920 1.00 92.25  ? 148 GLY A C   1 
ATOM 2492 O O   . GLY C 3 148 ? 357.440 305.804 453.908 1.00 92.25  ? 148 GLY A O   1 
ATOM 2493 N N   . PRO C 3 149 ? 358.938 304.402 453.017 1.00 87.19  ? 149 PRO A N   1 
ATOM 2494 C CA  . PRO C 3 149 ? 359.620 304.220 454.298 1.00 87.19  ? 149 PRO A CA  1 
ATOM 2495 C C   . PRO C 3 149 ? 360.467 305.426 454.660 1.00 87.19  ? 149 PRO A C   1 
ATOM 2496 O O   . PRO C 3 149 ? 360.622 306.371 453.886 1.00 87.19  ? 149 PRO A O   1 
ATOM 2497 C CB  . PRO C 3 149 ? 360.495 302.986 454.057 1.00 87.19  ? 149 PRO A CB  1 
ATOM 2498 C CG  . PRO C 3 149 ? 360.737 302.990 452.602 1.00 87.19  ? 149 PRO A CG  1 
ATOM 2499 C CD  . PRO C 3 149 ? 359.486 303.520 451.975 1.00 87.19  ? 149 PRO A CD  1 
ATOM 2500 N N   . VAL C 3 150 ? 361.015 305.384 455.867 1.00 91.92  ? 150 VAL A N   1 
ATOM 2501 C CA  . VAL C 3 150 ? 361.758 306.518 456.401 1.00 91.92  ? 150 VAL A CA  1 
ATOM 2502 C C   . VAL C 3 150 ? 362.966 305.993 457.174 1.00 91.92  ? 150 VAL A C   1 
ATOM 2503 O O   . VAL C 3 150 ? 362.882 304.941 457.825 1.00 91.92  ? 150 VAL A O   1 
ATOM 2504 C CB  . VAL C 3 150 ? 360.824 307.419 457.233 1.00 91.92  ? 150 VAL A CB  1 
ATOM 2505 C CG1 . VAL C 3 150 ? 360.352 306.744 458.516 1.00 91.92  ? 150 VAL A CG1 1 
ATOM 2506 C CG2 . VAL C 3 150 ? 361.467 308.748 457.542 1.00 91.92  ? 150 VAL A CG2 1 
ATOM 2507 N N   . PRO C 3 151 ? 364.130 306.620 457.054 1.00 89.64  ? 151 PRO A N   1 
ATOM 2508 C CA  . PRO C 3 151 ? 365.284 306.186 457.840 1.00 89.64  ? 151 PRO A CA  1 
ATOM 2509 C C   . PRO C 3 151 ? 365.409 306.976 459.130 1.00 89.64  ? 151 PRO A C   1 
ATOM 2510 O O   . PRO C 3 151 ? 365.218 308.190 459.170 1.00 89.64  ? 151 PRO A O   1 
ATOM 2511 C CB  . PRO C 3 151 ? 366.474 306.472 456.919 1.00 89.64  ? 151 PRO A CB  1 
ATOM 2512 C CG  . PRO C 3 151 ? 365.887 307.006 455.644 1.00 89.64  ? 151 PRO A CG  1 
ATOM 2513 C CD  . PRO C 3 151 ? 364.538 307.513 455.965 1.00 89.64  ? 151 PRO A CD  1 
ATOM 2514 N N   . THR C 3 152 ? 365.747 306.260 460.197 1.00 93.79  ? 152 THR A N   1 
ATOM 2515 C CA  . THR C 3 152 ? 365.952 306.882 461.497 1.00 93.79  ? 152 THR A CA  1 
ATOM 2516 C C   . THR C 3 152 ? 367.373 306.772 462.018 1.00 93.79  ? 152 THR A C   1 
ATOM 2517 O O   . THR C 3 152 ? 367.742 307.553 462.901 1.00 93.79  ? 152 THR A O   1 
ATOM 2518 C CB  . THR C 3 152 ? 365.009 306.279 462.545 1.00 93.79  ? 152 THR A CB  1 
ATOM 2519 O OG1 . THR C 3 152 ? 365.403 304.931 462.813 1.00 93.79  ? 152 THR A OG1 1 
ATOM 2520 C CG2 . THR C 3 152 ? 363.575 306.297 462.054 1.00 93.79  ? 152 THR A CG2 1 
ATOM 2521 N N   . LYS C 3 153 ? 368.175 305.840 461.520 1.00 98.48  ? 153 LYS A N   1 
ATOM 2522 C CA  . LYS C 3 153 ? 369.578 305.738 461.881 1.00 98.48  ? 153 LYS A CA  1 
ATOM 2523 C C   . LYS C 3 153 ? 370.408 305.775 460.609 1.00 98.48  ? 153 LYS A C   1 
ATOM 2524 O O   . LYS C 3 153 ? 369.876 305.762 459.497 1.00 98.48  ? 153 LYS A O   1 
ATOM 2525 C CB  . LYS C 3 153 ? 369.855 304.461 462.674 1.00 98.48  ? 153 LYS A CB  1 
ATOM 2526 C CG  . LYS C 3 153 ? 369.159 304.412 464.010 1.00 98.48  ? 153 LYS A CG  1 
ATOM 2527 C CD  . LYS C 3 153 ? 369.337 303.059 464.656 1.00 98.48  ? 153 LYS A CD  1 
ATOM 2528 C CE  . LYS C 3 153 ? 368.694 301.976 463.820 1.00 98.48  ? 153 LYS A CE  1 
ATOM 2529 N NZ  . LYS C 3 153 ? 368.887 300.637 464.431 1.00 98.48  ? 153 LYS A NZ  1 
ATOM 2530 N N   . VAL C 3 154 ? 371.727 305.825 460.771 1.00 94.02  ? 154 VAL A N   1 
ATOM 2531 C CA  . VAL C 3 154 ? 372.608 305.795 459.611 1.00 94.02  ? 154 VAL A CA  1 
ATOM 2532 C C   . VAL C 3 154 ? 372.601 304.410 458.986 1.00 94.02  ? 154 VAL A C   1 
ATOM 2533 O O   . VAL C 3 154 ? 372.179 304.229 457.840 1.00 94.02  ? 154 VAL A O   1 
ATOM 2534 C CB  . VAL C 3 154 ? 374.029 306.221 460.001 1.00 94.02  ? 154 VAL A CB  1 
ATOM 2535 C CG1 . VAL C 3 154 ? 374.904 306.270 458.778 1.00 94.02  ? 154 VAL A CG1 1 
ATOM 2536 C CG2 . VAL C 3 154 ? 373.993 307.562 460.682 1.00 94.02  ? 154 VAL A CG2 1 
ATOM 2537 N N   . LYS C 3 155 ? 373.040 303.409 459.738 1.00 99.78  ? 155 LYS A N   1 
ATOM 2538 C CA  . LYS C 3 155 ? 373.028 302.028 459.269 1.00 99.78  ? 155 LYS A CA  1 
ATOM 2539 C C   . LYS C 3 155 ? 371.626 301.484 459.498 1.00 99.78  ? 155 LYS A C   1 
ATOM 2540 O O   . LYS C 3 155 ? 371.246 301.172 460.627 1.00 99.78  ? 155 LYS A O   1 
ATOM 2541 C CB  . LYS C 3 155 ? 374.084 301.204 459.992 1.00 99.78  ? 155 LYS A CB  1 
ATOM 2542 C CG  . LYS C 3 155 ? 374.254 299.795 459.458 1.00 99.78  ? 155 LYS A CG  1 
ATOM 2543 C CD  . LYS C 3 155 ? 375.029 299.775 458.154 1.00 99.78  ? 155 LYS A CD  1 
ATOM 2544 C CE  . LYS C 3 155 ? 375.612 298.396 457.888 1.00 99.78  ? 155 LYS A CE  1 
ATOM 2545 N NZ  . LYS C 3 155 ? 374.565 297.338 457.853 1.00 99.78  ? 155 LYS A NZ  1 
ATOM 2546 N N   . ASP C 3 156 ? 370.849 301.376 458.427 1.00 105.60 ? 156 ASP A N   1 
ATOM 2547 C CA  . ASP C 3 156 ? 369.455 300.988 458.542 1.00 105.60 ? 156 ASP A CA  1 
ATOM 2548 C C   . ASP C 3 156 ? 369.034 300.286 457.262 1.00 105.60 ? 156 ASP A C   1 
ATOM 2549 O O   . ASP C 3 156 ? 369.669 300.431 456.216 1.00 105.60 ? 156 ASP A O   1 
ATOM 2550 C CB  . ASP C 3 156 ? 368.567 302.208 458.812 1.00 105.60 ? 156 ASP A CB  1 
ATOM 2551 C CG  . ASP C 3 156 ? 367.172 301.834 459.264 1.00 105.60 ? 156 ASP A CG  1 
ATOM 2552 O OD1 . ASP C 3 156 ? 366.345 301.491 458.392 1.00 105.60 ? 156 ASP A OD1 1 
ATOM 2553 O OD2 . ASP C 3 156 ? 366.909 301.870 460.482 1.00 105.60 ? 156 ASP A OD2 1 
ATOM 2554 N N   . TYR C 3 157 ? 367.951 299.513 457.362 1.00 108.96 ? 157 TYR A N   1 
ATOM 2555 C CA  . TYR C 3 157 ? 367.389 298.848 456.195 1.00 108.96 ? 157 TYR A CA  1 
ATOM 2556 C C   . TYR C 3 157 ? 366.822 299.844 455.195 1.00 108.96 ? 157 TYR A C   1 
ATOM 2557 O O   . TYR C 3 157 ? 366.891 299.604 453.985 1.00 108.96 ? 157 TYR A O   1 
ATOM 2558 C CB  . TYR C 3 157 ? 366.306 297.861 456.635 1.00 108.96 ? 157 TYR A CB  1 
ATOM 2559 C CG  . TYR C 3 157 ? 365.306 297.515 455.557 1.00 108.96 ? 157 TYR A CG  1 
ATOM 2560 C CD1 . TYR C 3 157 ? 365.668 296.710 454.484 1.00 108.96 ? 157 TYR A CD1 1 
ATOM 2561 C CD2 . TYR C 3 157 ? 364.004 297.998 455.607 1.00 108.96 ? 157 TYR A CD2 1 
ATOM 2562 C CE1 . TYR C 3 157 ? 364.764 296.397 453.491 1.00 108.96 ? 157 TYR A CE1 1 
ATOM 2563 C CE2 . TYR C 3 157 ? 363.094 297.688 454.619 1.00 108.96 ? 157 TYR A CE2 1 
ATOM 2564 C CZ  . TYR C 3 157 ? 363.481 296.887 453.565 1.00 108.96 ? 157 TYR A CZ  1 
ATOM 2565 O OH  . TYR C 3 157 ? 362.583 296.569 452.576 1.00 108.96 ? 157 TYR A OH  1 
ATOM 2566 N N   . ALA C 3 158 ? 366.302 300.977 455.676 1.00 96.08  ? 158 ALA A N   1 
ATOM 2567 C CA  . ALA C 3 158 ? 365.538 301.897 454.838 1.00 96.08  ? 158 ALA A CA  1 
ATOM 2568 C C   . ALA C 3 158 ? 366.364 302.544 453.734 1.00 96.08  ? 158 ALA A C   1 
ATOM 2569 O O   . ALA C 3 158 ? 365.789 303.053 452.769 1.00 96.08  ? 158 ALA A O   1 
ATOM 2570 C CB  . ALA C 3 158 ? 364.908 302.981 455.705 1.00 96.08  ? 158 ALA A CB  1 
ATOM 2571 N N   . TRP C 3 159 ? 367.689 302.532 453.844 1.00 90.95  ? 159 TRP A N   1 
ATOM 2572 C CA  . TRP C 3 159 ? 368.514 303.036 452.757 1.00 90.95  ? 159 TRP A CA  1 
ATOM 2573 C C   . TRP C 3 159 ? 368.602 302.037 451.615 1.00 90.95  ? 159 TRP A C   1 
ATOM 2574 O O   . TRP C 3 159 ? 368.688 302.429 450.448 1.00 90.95  ? 159 TRP A O   1 
ATOM 2575 C CB  . TRP C 3 159 ? 369.913 303.369 453.266 1.00 90.95  ? 159 TRP A CB  1 
ATOM 2576 C CG  . TRP C 3 159 ? 369.932 304.291 454.427 1.00 90.95  ? 159 TRP A CG  1 
ATOM 2577 C CD1 . TRP C 3 159 ? 369.855 303.951 455.737 1.00 90.95  ? 159 TRP A CD1 1 
ATOM 2578 C CD2 . TRP C 3 159 ? 370.047 305.710 454.387 1.00 90.95  ? 159 TRP A CD2 1 
ATOM 2579 N NE1 . TRP C 3 159 ? 369.912 305.071 456.520 1.00 90.95  ? 159 TRP A NE1 1 
ATOM 2580 C CE2 . TRP C 3 159 ? 370.032 306.166 455.710 1.00 90.95  ? 159 TRP A CE2 1 
ATOM 2581 C CE3 . TRP C 3 159 ? 370.161 306.639 453.360 1.00 90.95  ? 159 TRP A CE3 1 
ATOM 2582 C CZ2 . TRP C 3 159 ? 370.125 307.504 456.031 1.00 90.95  ? 159 TRP A CZ2 1 
ATOM 2583 C CZ3 . TRP C 3 159 ? 370.257 307.964 453.681 1.00 90.95  ? 159 TRP A CZ3 1 
ATOM 2584 C CH2 . TRP C 3 159 ? 370.237 308.387 455.003 1.00 90.95  ? 159 TRP A CH2 1 
ATOM 2585 N N   . GLN C 3 160 ? 368.577 300.744 451.926 1.00 96.07  ? 160 GLN A N   1 
ATOM 2586 C CA  . GLN C 3 160 ? 368.784 299.703 450.931 1.00 96.07  ? 160 GLN A CA  1 
ATOM 2587 C C   . GLN C 3 160 ? 367.487 299.218 450.307 1.00 96.07  ? 160 GLN A C   1 
ATOM 2588 O O   . GLN C 3 160 ? 367.416 298.065 449.869 1.00 96.07  ? 160 GLN A O   1 
ATOM 2589 C CB  . GLN C 3 160 ? 369.536 298.528 451.554 1.00 96.07  ? 160 GLN A CB  1 
ATOM 2590 C CG  . GLN C 3 160 ? 370.938 298.866 452.031 1.00 96.07  ? 160 GLN A CG  1 
ATOM 2591 C CD  . GLN C 3 160 ? 371.430 297.926 453.117 1.00 96.07  ? 160 GLN A CD  1 
ATOM 2592 O OE1 . GLN C 3 160 ? 370.774 296.937 453.439 1.00 96.07  ? 160 GLN A OE1 1 
ATOM 2593 N NE2 . GLN C 3 160 ? 372.592 298.230 453.683 1.00 96.07  ? 160 GLN A NE2 1 
ATOM 2594 N N   . THR C 3 161 ? 366.458 300.056 450.254 1.00 93.29  ? 161 THR A N   1 
ATOM 2595 C CA  . THR C 3 161 ? 365.173 299.611 449.743 1.00 93.29  ? 161 THR A CA  1 
ATOM 2596 C C   . THR C 3 161 ? 365.153 299.655 448.220 1.00 93.29  ? 161 THR A C   1 
ATOM 2597 O O   . THR C 3 161 ? 366.122 300.044 447.565 1.00 93.29  ? 161 THR A O   1 
ATOM 2598 C CB  . THR C 3 161 ? 364.043 300.456 450.309 1.00 93.29  ? 161 THR A CB  1 
ATOM 2599 O OG1 . THR C 3 161 ? 362.815 300.076 449.683 1.00 93.29  ? 161 THR A OG1 1 
ATOM 2600 C CG2 . THR C 3 161 ? 364.304 301.897 450.028 1.00 93.29  ? 161 THR A CG2 1 
ATOM 2601 N N   . SER C 3 162 ? 364.016 299.268 447.652 1.00 93.02  ? 162 SER A N   1 
ATOM 2602 C CA  . SER C 3 162 ? 363.923 298.980 446.228 1.00 93.02  ? 162 SER A CA  1 
ATOM 2603 C C   . SER C 3 162 ? 363.477 300.163 445.390 1.00 93.02  ? 162 SER A C   1 
ATOM 2604 O O   . SER C 3 162 ? 364.125 300.475 444.388 1.00 93.02  ? 162 SER A O   1 
ATOM 2605 C CB  . SER C 3 162 ? 362.949 297.822 445.994 1.00 93.02  ? 162 SER A CB  1 
ATOM 2606 O OG  . SER C 3 162 ? 363.396 296.645 446.639 1.00 93.02  ? 162 SER A OG  1 
ATOM 2607 N N   . THR C 3 163 ? 362.389 300.827 445.772 1.00 94.47  ? 163 THR A N   1 
ATOM 2608 C CA  . THR C 3 163 ? 361.766 301.845 444.942 1.00 94.47  ? 163 THR A CA  1 
ATOM 2609 C C   . THR C 3 163 ? 362.024 303.261 445.437 1.00 94.47  ? 163 THR A C   1 
ATOM 2610 O O   . THR C 3 163 ? 361.253 304.171 445.121 1.00 94.47  ? 163 THR A O   1 
ATOM 2611 C CB  . THR C 3 163 ? 360.268 301.587 444.843 1.00 94.47  ? 163 THR A CB  1 
ATOM 2612 O OG1 . THR C 3 163 ? 359.664 302.611 444.048 1.00 94.47  ? 163 THR A OG1 1 
ATOM 2613 C CG2 . THR C 3 163 ? 359.642 301.554 446.222 1.00 94.47  ? 163 THR A CG2 1 
ATOM 2614 N N   . ASN C 3 164 ? 363.095 303.473 446.188 1.00 88.38  ? 164 ASN A N   1 
ATOM 2615 C CA  . ASN C 3 164 ? 363.511 304.825 446.535 1.00 88.38  ? 164 ASN A CA  1 
ATOM 2616 C C   . ASN C 3 164 ? 364.724 305.167 445.693 1.00 88.38  ? 164 ASN A C   1 
ATOM 2617 O O   . ASN C 3 164 ? 365.833 304.704 445.993 1.00 88.38  ? 164 ASN A O   1 
ATOM 2618 C CB  . ASN C 3 164 ? 363.841 304.938 448.021 1.00 88.38  ? 164 ASN A CB  1 
ATOM 2619 C CG  . ASN C 3 164 ? 362.617 304.868 448.895 1.00 88.38  ? 164 ASN A CG  1 
ATOM 2620 O OD1 . ASN C 3 164 ? 362.722 304.835 450.116 1.00 88.38  ? 164 ASN A OD1 1 
ATOM 2621 N ND2 . ASN C 3 164 ? 361.445 304.844 448.278 1.00 88.38  ? 164 ASN A ND2 1 
ATOM 2622 N N   . PRO C 3 165 ? 364.573 305.948 444.628 1.00 83.62  ? 165 PRO A N   1 
ATOM 2623 C CA  . PRO C 3 165 ? 365.703 306.196 443.726 1.00 83.62  ? 165 PRO A CA  1 
ATOM 2624 C C   . PRO C 3 165 ? 366.726 307.119 444.366 1.00 83.62  ? 165 PRO A C   1 
ATOM 2625 O O   . PRO C 3 165 ? 366.381 308.159 444.926 1.00 83.62  ? 165 PRO A O   1 
ATOM 2626 C CB  . PRO C 3 165 ? 365.045 306.845 442.508 1.00 83.62  ? 165 PRO A CB  1 
ATOM 2627 C CG  . PRO C 3 165 ? 363.797 307.441 443.033 1.00 83.62  ? 165 PRO A CG  1 
ATOM 2628 C CD  . PRO C 3 165 ? 363.331 306.571 444.150 1.00 83.62  ? 165 PRO A CD  1 
ATOM 2629 N N   . SER C 3 166 ? 367.988 306.720 444.288 1.00 79.90  ? 166 SER A N   1 
ATOM 2630 C CA  . SER C 3 166 ? 369.070 307.433 444.941 1.00 79.90  ? 166 SER A CA  1 
ATOM 2631 C C   . SER C 3 166 ? 370.245 307.551 443.991 1.00 79.90  ? 166 SER A C   1 
ATOM 2632 O O   . SER C 3 166 ? 370.488 306.670 443.167 1.00 79.90  ? 166 SER A O   1 
ATOM 2633 C CB  . SER C 3 166 ? 369.512 306.714 446.205 1.00 79.90  ? 166 SER A CB  1 
ATOM 2634 O OG  . SER C 3 166 ? 369.817 305.369 445.907 1.00 79.90  ? 166 SER A OG  1 
ATOM 2635 N N   . VAL C 3 167 ? 370.986 308.641 444.121 1.00 75.02  ? 167 VAL A N   1 
ATOM 2636 C CA  . VAL C 3 167 ? 372.160 308.874 443.295 1.00 75.02  ? 167 VAL A CA  1 
ATOM 2637 C C   . VAL C 3 167 ? 373.395 308.579 444.125 1.00 75.02  ? 167 VAL A C   1 
ATOM 2638 O O   . VAL C 3 167 ? 373.334 308.477 445.353 1.00 75.02  ? 167 VAL A O   1 
ATOM 2639 C CB  . VAL C 3 167 ? 372.199 310.309 442.743 1.00 75.02  ? 167 VAL A CB  1 
ATOM 2640 C CG1 . VAL C 3 167 ? 370.865 310.660 442.148 1.00 75.02  ? 167 VAL A CG1 1 
ATOM 2641 C CG2 . VAL C 3 167 ? 372.561 311.284 443.827 1.00 75.02  ? 167 VAL A CG2 1 
ATOM 2642 N N   . PHE C 3 168 ? 374.519 308.404 443.447 1.00 72.86  ? 168 PHE A N   1 
ATOM 2643 C CA  . PHE C 3 168 ? 375.795 308.170 444.100 1.00 72.86  ? 168 PHE A CA  1 
ATOM 2644 C C   . PHE C 3 168 ? 376.838 309.051 443.445 1.00 72.86  ? 168 PHE A C   1 
ATOM 2645 O O   . PHE C 3 168 ? 377.128 308.893 442.257 1.00 72.86  ? 168 PHE A O   1 
ATOM 2646 C CB  . PHE C 3 168 ? 376.207 306.710 444.001 1.00 72.86  ? 168 PHE A CB  1 
ATOM 2647 C CG  . PHE C 3 168 ? 375.560 305.831 445.018 1.00 72.86  ? 168 PHE A CG  1 
ATOM 2648 C CD1 . PHE C 3 168 ? 374.272 305.378 444.839 1.00 72.86  ? 168 PHE A CD1 1 
ATOM 2649 C CD2 . PHE C 3 168 ? 376.249 305.448 446.148 1.00 72.86  ? 168 PHE A CD2 1 
ATOM 2650 C CE1 . PHE C 3 168 ? 373.680 304.567 445.772 1.00 72.86  ? 168 PHE A CE1 1 
ATOM 2651 C CE2 . PHE C 3 168 ? 375.661 304.637 447.084 1.00 72.86  ? 168 PHE A CE2 1 
ATOM 2652 C CZ  . PHE C 3 168 ? 374.377 304.196 446.894 1.00 72.86  ? 168 PHE A CZ  1 
ATOM 2653 N N   . TRP C 3 169 ? 377.410 309.963 444.218 1.00 78.12  ? 169 TRP A N   1 
ATOM 2654 C CA  . TRP C 3 169 ? 378.256 311.009 443.669 1.00 78.12  ? 169 TRP A CA  1 
ATOM 2655 C C   . TRP C 3 169 ? 379.571 311.022 444.420 1.00 78.12  ? 169 TRP A C   1 
ATOM 2656 O O   . TRP C 3 169 ? 379.579 311.128 445.648 1.00 78.12  ? 169 TRP A O   1 
ATOM 2657 C CB  . TRP C 3 169 ? 377.568 312.362 443.784 1.00 78.12  ? 169 TRP A CB  1 
ATOM 2658 C CG  . TRP C 3 169 ? 378.346 313.480 443.240 1.00 78.12  ? 169 TRP A CG  1 
ATOM 2659 C CD1 . TRP C 3 169 ? 378.370 313.900 441.955 1.00 78.12  ? 169 TRP A CD1 1 
ATOM 2660 C CD2 . TRP C 3 169 ? 379.199 314.358 443.966 1.00 78.12  ? 169 TRP A CD2 1 
ATOM 2661 N NE1 . TRP C 3 169 ? 379.193 314.983 441.826 1.00 78.12  ? 169 TRP A NE1 1 
ATOM 2662 C CE2 . TRP C 3 169 ? 379.716 315.283 443.052 1.00 78.12  ? 169 TRP A CE2 1 
ATOM 2663 C CE3 . TRP C 3 169 ? 379.586 314.443 445.298 1.00 78.12  ? 169 TRP A CE3 1 
ATOM 2664 C CZ2 . TRP C 3 169 ? 380.601 316.279 443.426 1.00 78.12  ? 169 TRP A CZ2 1 
ATOM 2665 C CZ3 . TRP C 3 169 ? 380.460 315.435 445.669 1.00 78.12  ? 169 TRP A CZ3 1 
ATOM 2666 C CH2 . TRP C 3 169 ? 380.959 316.340 444.739 1.00 78.12  ? 169 TRP A CH2 1 
ATOM 2667 N N   . THR C 3 170 ? 380.671 310.907 443.690 1.00 82.13  ? 170 THR A N   1 
ATOM 2668 C CA  . THR C 3 170 ? 381.979 311.047 444.298 1.00 82.13  ? 170 THR A CA  1 
ATOM 2669 C C   . THR C 3 170 ? 382.467 312.478 444.140 1.00 82.13  ? 170 THR A C   1 
ATOM 2670 O O   . THR C 3 170 ? 381.998 313.223 443.282 1.00 82.13  ? 170 THR A O   1 
ATOM 2671 C CB  . THR C 3 170 ? 382.977 310.103 443.654 1.00 82.13  ? 170 THR A CB  1 
ATOM 2672 O OG1 . THR C 3 170 ? 383.168 310.492 442.294 1.00 82.13  ? 170 THR A OG1 1 
ATOM 2673 C CG2 . THR C 3 170 ? 382.439 308.703 443.672 1.00 82.13  ? 170 THR A CG2 1 
ATOM 2674 N N   . GLU C 3 171 ? 383.429 312.857 444.966 1.00 90.60  ? 171 GLU A N   1 
ATOM 2675 C CA  . GLU C 3 171 ? 383.972 314.203 444.915 1.00 90.60  ? 171 GLU A CA  1 
ATOM 2676 C C   . GLU C 3 171 ? 384.854 314.377 443.690 1.00 90.60  ? 171 GLU A C   1 
ATOM 2677 O O   . GLU C 3 171 ? 385.249 313.401 443.050 1.00 90.60  ? 171 GLU A O   1 
ATOM 2678 C CB  . GLU C 3 171 ? 384.771 314.513 446.174 1.00 90.60  ? 171 GLU A CB  1 
ATOM 2679 C CG  . GLU C 3 171 ? 383.930 315.080 447.282 1.00 90.60  ? 171 GLU A CG  1 
ATOM 2680 C CD  . GLU C 3 171 ? 384.766 315.704 448.368 1.00 90.60  ? 171 GLU A CD  1 
ATOM 2681 O OE1 . GLU C 3 171 ? 384.865 315.110 449.460 1.00 90.60  ? 171 GLU A OE1 1 
ATOM 2682 O OE2 . GLU C 3 171 ? 385.336 316.786 448.126 1.00 90.60  ? 171 GLU A OE2 1 
ATOM 2683 N N   . GLY C 3 172 ? 385.149 315.626 443.362 1.00 88.02  ? 172 GLY A N   1 
ATOM 2684 C CA  . GLY C 3 172 ? 385.992 315.935 442.233 1.00 88.02  ? 172 GLY A CA  1 
ATOM 2685 C C   . GLY C 3 172 ? 385.323 315.846 440.883 1.00 88.02  ? 172 GLY A C   1 
ATOM 2686 O O   . GLY C 3 172 ? 386.026 315.802 439.870 1.00 88.02  ? 172 GLY A O   1 
ATOM 2687 N N   . ASN C 3 173 ? 383.997 315.816 440.833 1.00 86.45  ? 173 ASN A N   1 
ATOM 2688 C CA  . ASN C 3 173 ? 383.290 315.713 439.567 1.00 86.45  ? 173 ASN A CA  1 
ATOM 2689 C C   . ASN C 3 173 ? 382.291 316.848 439.438 1.00 86.45  ? 173 ASN A C   1 
ATOM 2690 O O   . ASN C 3 173 ? 382.315 317.793 440.229 1.00 86.45  ? 173 ASN A O   1 
ATOM 2691 C CB  . ASN C 3 173 ? 382.577 314.367 439.456 1.00 86.45  ? 173 ASN A CB  1 
ATOM 2692 C CG  . ASN C 3 173 ? 383.523 313.232 439.158 1.00 86.45  ? 173 ASN A CG  1 
ATOM 2693 O OD1 . ASN C 3 173 ? 383.544 312.706 438.049 1.00 86.45  ? 173 ASN A OD1 1 
ATOM 2694 N ND2 . ASN C 3 173 ? 384.317 312.848 440.144 1.00 86.45  ? 173 ASN A ND2 1 
ATOM 2695 N N   . ALA C 3 174 ? 381.425 316.774 438.437 1.00 85.76  ? 174 ALA A N   1 
ATOM 2696 C CA  . ALA C 3 174 ? 380.346 317.732 438.327 1.00 85.76  ? 174 ALA A CA  1 
ATOM 2697 C C   . ALA C 3 174 ? 379.311 317.470 439.421 1.00 85.76  ? 174 ALA A C   1 
ATOM 2698 O O   . ALA C 3 174 ? 379.190 316.344 439.907 1.00 85.76  ? 174 ALA A O   1 
ATOM 2699 C CB  . ALA C 3 174 ? 379.699 317.638 436.952 1.00 85.76  ? 174 ALA A CB  1 
ATOM 2700 N N   . PRO C 3 175 ? 378.579 318.501 439.851 1.00 81.89  ? 175 PRO A N   1 
ATOM 2701 C CA  . PRO C 3 175 ? 377.587 318.303 440.905 1.00 81.89  ? 175 PRO A CA  1 
ATOM 2702 C C   . PRO C 3 175 ? 376.409 317.478 440.424 1.00 81.89  ? 175 PRO A C   1 
ATOM 2703 O O   . PRO C 3 175 ? 376.006 317.564 439.251 1.00 81.89  ? 175 PRO A O   1 
ATOM 2704 C CB  . PRO C 3 175 ? 377.162 319.739 441.259 1.00 81.89  ? 175 PRO A CB  1 
ATOM 2705 C CG  . PRO C 3 175 ? 377.694 320.580 440.183 1.00 81.89  ? 175 PRO A CG  1 
ATOM 2706 C CD  . PRO C 3 175 ? 378.918 319.921 439.707 1.00 81.89  ? 175 PRO A CD  1 
ATOM 2707 N N   . PRO C 3 176 ? 375.814 316.660 441.301 1.00 76.11  ? 176 PRO A N   1 
ATOM 2708 C CA  . PRO C 3 176 ? 374.831 315.656 440.868 1.00 76.11  ? 176 PRO A CA  1 
ATOM 2709 C C   . PRO C 3 176 ? 373.403 316.144 440.680 1.00 76.11  ? 176 PRO A C   1 
ATOM 2710 O O   . PRO C 3 176 ? 372.594 316.063 441.605 1.00 76.11  ? 176 PRO A O   1 
ATOM 2711 C CB  . PRO C 3 176 ? 374.897 314.617 441.988 1.00 76.11  ? 176 PRO A CB  1 
ATOM 2712 C CG  . PRO C 3 176 ? 375.330 315.366 443.173 1.00 76.11  ? 176 PRO A CG  1 
ATOM 2713 C CD  . PRO C 3 176 ? 376.157 316.518 442.723 1.00 76.11  ? 176 PRO A CD  1 
ATOM 2714 N N   . ARG C 3 177 ? 373.073 316.650 439.501 1.00 81.91  ? 177 ARG A N   1 
ATOM 2715 C CA  . ARG C 3 177 ? 371.705 317.064 439.224 1.00 81.91  ? 177 ARG A CA  1 
ATOM 2716 C C   . ARG C 3 177 ? 370.772 315.862 439.110 1.00 81.91  ? 177 ARG A C   1 
ATOM 2717 O O   . ARG C 3 177 ? 371.139 314.812 438.586 1.00 81.91  ? 177 ARG A O   1 
ATOM 2718 C CB  . ARG C 3 177 ? 371.662 317.874 437.930 1.00 81.91  ? 177 ARG A CB  1 
ATOM 2719 C CG  . ARG C 3 177 ? 370.375 318.623 437.690 1.00 81.91  ? 177 ARG A CG  1 
ATOM 2720 C CD  . ARG C 3 177 ? 370.257 319.064 436.254 1.00 81.91  ? 177 ARG A CD  1 
ATOM 2721 N NE  . ARG C 3 177 ? 371.349 319.944 435.872 1.00 81.91  ? 177 ARG A NE  1 
ATOM 2722 C CZ  . ARG C 3 177 ? 371.347 321.254 436.071 1.00 81.91  ? 177 ARG A CZ  1 
ATOM 2723 N NH1 . ARG C 3 177 ? 370.307 321.836 436.646 1.00 81.91  ? 177 ARG A NH1 1 
ATOM 2724 N NH2 . ARG C 3 177 ? 372.382 321.984 435.691 1.00 81.91  ? 177 ARG A NH2 1 
ATOM 2725 N N   . MET C 3 178 ? 369.555 316.024 439.623 1.00 85.42  ? 178 MET A N   1 
ATOM 2726 C CA  . MET C 3 178 ? 368.469 315.079 439.407 1.00 85.42  ? 178 MET A CA  1 
ATOM 2727 C C   . MET C 3 178 ? 367.183 315.877 439.278 1.00 85.42  ? 178 MET A C   1 
ATOM 2728 O O   . MET C 3 178 ? 367.133 317.054 439.636 1.00 85.42  ? 178 MET A O   1 
ATOM 2729 C CB  . MET C 3 178 ? 368.364 314.062 440.545 1.00 85.42  ? 178 MET A CB  1 
ATOM 2730 C CG  . MET C 3 178 ? 367.573 314.548 441.740 1.00 85.42  ? 178 MET A CG  1 
ATOM 2731 S SD  . MET C 3 178 ? 367.874 313.603 443.240 1.00 85.42  ? 178 MET A SD  1 
ATOM 2732 C CE  . MET C 3 178 ? 367.274 312.000 442.748 1.00 85.42  ? 178 MET A CE  1 
ATOM 2733 N N   . SER C 3 179 ? 366.135 315.241 438.762 1.00 89.32  ? 179 SER A N   1 
ATOM 2734 C CA  . SER C 3 179 ? 364.878 315.944 438.531 1.00 89.32  ? 179 SER A CA  1 
ATOM 2735 C C   . SER C 3 179 ? 363.692 315.084 438.929 1.00 89.32  ? 179 SER A C   1 
ATOM 2736 O O   . SER C 3 179 ? 363.636 313.900 438.591 1.00 89.32  ? 179 SER A O   1 
ATOM 2737 C CB  . SER C 3 179 ? 364.730 316.348 437.071 1.00 89.32  ? 179 SER A CB  1 
ATOM 2738 O OG  . SER C 3 179 ? 364.529 315.210 436.265 1.00 89.32  ? 179 SER A OG  1 
ATOM 2739 N N   . ILE C 3 180 ? 362.738 315.695 439.611 1.00 85.03  ? 180 ILE A N   1 
ATOM 2740 C CA  . ILE C 3 180 ? 361.525 315.035 440.081 1.00 85.03  ? 180 ILE A CA  1 
ATOM 2741 C C   . ILE C 3 180 ? 360.368 315.542 439.237 1.00 85.03  ? 180 ILE A C   1 
ATOM 2742 O O   . ILE C 3 180 ? 360.214 316.759 439.094 1.00 85.03  ? 180 ILE A O   1 
ATOM 2743 C CB  . ILE C 3 180 ? 361.265 315.334 441.564 1.00 85.03  ? 180 ILE A CB  1 
ATOM 2744 C CG1 . ILE C 3 180 ? 362.458 314.916 442.402 1.00 85.03  ? 180 ILE A CG1 1 
ATOM 2745 C CG2 . ILE C 3 180 ? 360.037 314.616 442.044 1.00 85.03  ? 180 ILE A CG2 1 
ATOM 2746 C CD1 . ILE C 3 180 ? 362.377 315.414 443.808 1.00 85.03  ? 180 ILE A CD1 1 
ATOM 2747 N N   . PRO C 3 181 ? 359.539 314.677 438.678 1.00 88.05  ? 181 PRO A N   1 
ATOM 2748 C CA  . PRO C 3 181 ? 358.386 315.142 437.911 1.00 88.05  ? 181 PRO A CA  1 
ATOM 2749 C C   . PRO C 3 181 ? 357.252 315.539 438.847 1.00 88.05  ? 181 PRO A C   1 
ATOM 2750 O O   . PRO C 3 181 ? 357.371 315.494 440.066 1.00 88.05  ? 181 PRO A O   1 
ATOM 2751 C CB  . PRO C 3 181 ? 358.024 313.932 437.063 1.00 88.05  ? 181 PRO A CB  1 
ATOM 2752 C CG  . PRO C 3 181 ? 358.389 312.802 437.913 1.00 88.05  ? 181 PRO A CG  1 
ATOM 2753 C CD  . PRO C 3 181 ? 359.624 313.211 438.670 1.00 88.05  ? 181 PRO A CD  1 
ATOM 2754 N N   . PHE C 3 182 ? 356.132 315.922 438.248 1.00 94.47  ? 182 PHE A N   1 
ATOM 2755 C CA  . PHE C 3 182 ? 354.997 316.467 438.987 1.00 94.47  ? 182 PHE A CA  1 
ATOM 2756 C C   . PHE C 3 182 ? 354.264 315.324 439.681 1.00 94.47  ? 182 PHE A C   1 
ATOM 2757 O O   . PHE C 3 182 ? 353.572 314.537 439.039 1.00 94.47  ? 182 PHE A O   1 
ATOM 2758 C CB  . PHE C 3 182 ? 354.096 317.231 438.029 1.00 94.47  ? 182 PHE A CB  1 
ATOM 2759 C CG  . PHE C 3 182 ? 352.751 317.544 438.577 1.00 94.47  ? 182 PHE A CG  1 
ATOM 2760 C CD1 . PHE C 3 182 ? 352.617 318.298 439.724 1.00 94.47  ? 182 PHE A CD1 1 
ATOM 2761 C CD2 . PHE C 3 182 ? 351.617 317.110 437.925 1.00 94.47  ? 182 PHE A CD2 1 
ATOM 2762 C CE1 . PHE C 3 182 ? 351.373 318.593 440.219 1.00 94.47  ? 182 PHE A CE1 1 
ATOM 2763 C CE2 . PHE C 3 182 ? 350.372 317.403 438.415 1.00 94.47  ? 182 PHE A CE2 1 
ATOM 2764 C CZ  . PHE C 3 182 ? 350.249 318.144 439.563 1.00 94.47  ? 182 PHE A CZ  1 
ATOM 2765 N N   . ILE C 3 183 ? 354.402 315.232 441.000 1.00 94.85  ? 183 ILE A N   1 
ATOM 2766 C CA  . ILE C 3 183 ? 353.947 314.071 441.759 1.00 94.85  ? 183 ILE A CA  1 
ATOM 2767 C C   . ILE C 3 183 ? 352.810 314.483 442.688 1.00 94.85  ? 183 ILE A C   1 
ATOM 2768 O O   . ILE C 3 183 ? 353.034 314.864 443.843 1.00 94.85  ? 183 ILE A O   1 
ATOM 2769 C CB  . ILE C 3 183 ? 355.099 313.427 442.542 1.00 94.85  ? 183 ILE A CB  1 
ATOM 2770 C CG1 . ILE C 3 183 ? 356.065 314.491 443.066 1.00 94.85  ? 183 ILE A CG1 1 
ATOM 2771 C CG2 . ILE C 3 183 ? 355.855 312.458 441.674 1.00 94.85  ? 183 ILE A CG2 1 
ATOM 2772 C CD1 . ILE C 3 183 ? 356.732 314.107 444.348 1.00 94.85  ? 183 ILE A CD1 1 
ATOM 2773 N N   . SER C 3 184 ? 351.576 314.358 442.212 1.00 97.85  ? 184 SER A N   1 
ATOM 2774 C CA  . SER C 3 184 ? 350.426 314.592 443.072 1.00 97.85  ? 184 SER A CA  1 
ATOM 2775 C C   . SER C 3 184 ? 349.232 313.857 442.495 1.00 97.85  ? 184 SER A C   1 
ATOM 2776 O O   . SER C 3 184 ? 349.082 313.740 441.276 1.00 97.85  ? 184 SER A O   1 
ATOM 2777 C CB  . SER C 3 184 ? 350.110 316.081 443.215 1.00 97.85  ? 184 SER A CB  1 
ATOM 2778 O OG  . SER C 3 184 ? 349.324 316.307 444.367 1.00 97.85  ? 184 SER A OG  1 
ATOM 2779 N N   . ILE C 3 185 ? 348.382 313.361 443.393 1.00 97.70  ? 185 ILE A N   1 
ATOM 2780 C CA  . ILE C 3 185 ? 347.174 312.668 442.966 1.00 97.70  ? 185 ILE A CA  1 
ATOM 2781 C C   . ILE C 3 185 ? 346.203 313.646 442.323 1.00 97.70  ? 185 ILE A C   1 
ATOM 2782 O O   . ILE C 3 185 ? 345.612 313.355 441.279 1.00 97.70  ? 185 ILE A O   1 
ATOM 2783 C CB  . ILE C 3 185 ? 346.544 311.928 444.157 1.00 97.70  ? 185 ILE A CB  1 
ATOM 2784 C CG1 . ILE C 3 185 ? 347.545 310.940 444.765 1.00 97.70  ? 185 ILE A CG1 1 
ATOM 2785 C CG2 . ILE C 3 185 ? 345.276 311.207 443.738 1.00 97.70  ? 185 ILE A CG2 1 
ATOM 2786 C CD1 . ILE C 3 185 ? 347.772 309.684 443.947 1.00 97.70  ? 185 ILE A CD1 1 
ATOM 2787 N N   . GLY C 3 186 ? 346.062 314.832 442.901 1.00 99.05  ? 186 GLY A N   1 
ATOM 2788 C CA  . GLY C 3 186 ? 345.257 315.871 442.293 1.00 99.05  ? 186 GLY A CA  1 
ATOM 2789 C C   . GLY C 3 186 ? 345.910 316.465 441.058 1.00 99.05  ? 186 GLY A C   1 
ATOM 2790 O O   . GLY C 3 186 ? 346.970 316.044 440.598 1.00 99.05  ? 186 GLY A O   1 
ATOM 2791 N N   . ASN C 3 187 ? 345.260 317.485 440.511 1.00 100.41 ? 187 ASN A N   1 
ATOM 2792 C CA  . ASN C 3 187 ? 345.713 318.018 439.238 1.00 100.41 ? 187 ASN A CA  1 
ATOM 2793 C C   . ASN C 3 187 ? 346.695 319.169 439.366 1.00 100.41 ? 187 ASN A C   1 
ATOM 2794 O O   . ASN C 3 187 ? 347.343 319.506 438.373 1.00 100.41 ? 187 ASN A O   1 
ATOM 2795 C CB  . ASN C 3 187 ? 344.520 318.464 438.410 1.00 100.41 ? 187 ASN A CB  1 
ATOM 2796 C CG  . ASN C 3 187 ? 343.775 317.305 437.823 1.00 100.41 ? 187 ASN A CG  1 
ATOM 2797 O OD1 . ASN C 3 187 ? 343.263 316.454 438.547 1.00 100.41 ? 187 ASN A OD1 1 
ATOM 2798 N ND2 . ASN C 3 187 ? 343.714 317.251 436.504 1.00 100.41 ? 187 ASN A ND2 1 
ATOM 2799 N N   . ALA C 3 188 ? 346.836 319.772 440.541 1.00 93.13  ? 188 ALA A N   1 
ATOM 2800 C CA  . ALA C 3 188 ? 347.743 320.901 440.671 1.00 93.13  ? 188 ALA A CA  1 
ATOM 2801 C C   . ALA C 3 188 ? 348.191 321.023 442.115 1.00 93.13  ? 188 ALA A C   1 
ATOM 2802 O O   . ALA C 3 188 ? 347.514 320.549 443.027 1.00 93.13  ? 188 ALA A O   1 
ATOM 2803 C CB  . ALA C 3 188 ? 347.080 322.202 440.218 1.00 93.13  ? 188 ALA A CB  1 
ATOM 2804 N N   . TYR C 3 189 ? 349.339 321.661 442.313 1.00 95.29  ? 189 TYR A N   1 
ATOM 2805 C CA  . TYR C 3 189 ? 349.735 322.018 443.661 1.00 95.29  ? 189 TYR A CA  1 
ATOM 2806 C C   . TYR C 3 189 ? 348.884 323.177 444.153 1.00 95.29  ? 189 TYR A C   1 
ATOM 2807 O O   . TYR C 3 189 ? 348.592 324.122 443.421 1.00 95.29  ? 189 TYR A O   1 
ATOM 2808 C CB  . TYR C 3 189 ? 351.208 322.405 443.718 1.00 95.29  ? 189 TYR A CB  1 
ATOM 2809 C CG  . TYR C 3 189 ? 352.154 321.272 443.427 1.00 95.29  ? 189 TYR A CG  1 
ATOM 2810 C CD1 . TYR C 3 189 ? 351.814 319.964 443.718 1.00 95.29  ? 189 TYR A CD1 1 
ATOM 2811 C CD2 . TYR C 3 189 ? 353.392 321.514 442.863 1.00 95.29  ? 189 TYR A CD2 1 
ATOM 2812 C CE1 . TYR C 3 189 ? 352.681 318.932 443.452 1.00 95.29  ? 189 TYR A CE1 1 
ATOM 2813 C CE2 . TYR C 3 189 ? 354.263 320.489 442.591 1.00 95.29  ? 189 TYR A CE2 1 
ATOM 2814 C CZ  . TYR C 3 189 ? 353.902 319.202 442.886 1.00 95.29  ? 189 TYR A CZ  1 
ATOM 2815 O OH  . TYR C 3 189 ? 354.773 318.178 442.613 1.00 95.29  ? 189 TYR A OH  1 
ATOM 2816 N N   . SER C 3 190 ? 348.487 323.102 445.413 1.00 95.08  ? 190 SER A N   1 
ATOM 2817 C CA  . SER C 3 190 ? 347.598 324.090 446.008 1.00 95.08  ? 190 SER A CA  1 
ATOM 2818 C C   . SER C 3 190 ? 348.394 324.909 447.008 1.00 95.08  ? 190 SER A C   1 
ATOM 2819 O O   . SER C 3 190 ? 348.763 324.406 448.072 1.00 95.08  ? 190 SER A O   1 
ATOM 2820 C CB  . SER C 3 190 ? 346.409 323.415 446.680 1.00 95.08  ? 190 SER A CB  1 
ATOM 2821 O OG  . SER C 3 190 ? 345.622 322.726 445.728 1.00 95.08  ? 190 SER A OG  1 
ATOM 2822 N N   . CYS C 3 191 ? 348.652 326.168 446.673 1.00 92.16  ? 191 CYS A N   1 
ATOM 2823 C CA  . CYS C 3 191 ? 349.415 327.020 447.568 1.00 92.16  ? 191 CYS A CA  1 
ATOM 2824 C C   . CYS C 3 191 ? 348.594 327.513 448.749 1.00 92.16  ? 191 CYS A C   1 
ATOM 2825 O O   . CYS C 3 191 ? 349.174 327.978 449.733 1.00 92.16  ? 191 CYS A O   1 
ATOM 2826 C CB  . CYS C 3 191 ? 349.982 328.208 446.801 1.00 92.16  ? 191 CYS A CB  1 
ATOM 2827 S SG  . CYS C 3 191 ? 351.545 327.860 445.990 1.00 92.16  ? 191 CYS A SG  1 
ATOM 2828 N N   . PHE C 3 192 ? 347.271 327.426 448.678 1.00 92.92  ? 192 PHE A N   1 
ATOM 2829 C CA  . PHE C 3 192 ? 346.415 327.820 449.785 1.00 92.92  ? 192 PHE A CA  1 
ATOM 2830 C C   . PHE C 3 192 ? 345.313 326.793 449.951 1.00 92.92  ? 192 PHE A C   1 
ATOM 2831 O O   . PHE C 3 192 ? 344.928 326.109 449.002 1.00 92.92  ? 192 PHE A O   1 
ATOM 2832 C CB  . PHE C 3 192 ? 345.807 329.199 449.566 1.00 92.92  ? 192 PHE A CB  1 
ATOM 2833 C CG  . PHE C 3 192 ? 346.745 330.313 449.848 1.00 92.92  ? 192 PHE A CG  1 
ATOM 2834 C CD1 . PHE C 3 192 ? 347.572 330.800 448.862 1.00 92.92  ? 192 PHE A CD1 1 
ATOM 2835 C CD2 . PHE C 3 192 ? 346.805 330.875 451.103 1.00 92.92  ? 192 PHE A CD2 1 
ATOM 2836 C CE1 . PHE C 3 192 ? 348.443 331.826 449.124 1.00 92.92  ? 192 PHE A CE1 1 
ATOM 2837 C CE2 . PHE C 3 192 ? 347.673 331.906 451.368 1.00 92.92  ? 192 PHE A CE2 1 
ATOM 2838 C CZ  . PHE C 3 192 ? 348.491 332.382 450.376 1.00 92.92  ? 192 PHE A CZ  1 
ATOM 2839 N N   . TYR C 3 193 ? 344.793 326.701 451.170 1.00 99.24  ? 193 TYR A N   1 
ATOM 2840 C CA  . TYR C 3 193 ? 343.773 325.706 451.477 1.00 99.24  ? 193 TYR A CA  1 
ATOM 2841 C C   . TYR C 3 193 ? 342.991 326.172 452.691 1.00 99.24  ? 193 TYR A C   1 
ATOM 2842 O O   . TYR C 3 193 ? 343.547 326.261 453.785 1.00 99.24  ? 193 TYR A O   1 
ATOM 2843 C CB  . TYR C 3 193 ? 344.402 324.347 451.734 1.00 99.24  ? 193 TYR A CB  1 
ATOM 2844 C CG  . TYR C 3 193 ? 343.402 323.232 451.829 1.00 99.24  ? 193 TYR A CG  1 
ATOM 2845 C CD1 . TYR C 3 193 ? 342.909 322.626 450.687 1.00 99.24  ? 193 TYR A CD1 1 
ATOM 2846 C CD2 . TYR C 3 193 ? 342.963 322.773 453.059 1.00 99.24  ? 193 TYR A CD2 1 
ATOM 2847 C CE1 . TYR C 3 193 ? 342.003 321.599 450.767 1.00 99.24  ? 193 TYR A CE1 1 
ATOM 2848 C CE2 . TYR C 3 193 ? 342.058 321.750 453.147 1.00 99.24  ? 193 TYR A CE2 1 
ATOM 2849 C CZ  . TYR C 3 193 ? 341.581 321.168 452.000 1.00 99.24  ? 193 TYR A CZ  1 
ATOM 2850 O OH  . TYR C 3 193 ? 340.673 320.143 452.086 1.00 99.24  ? 193 TYR A OH  1 
ATOM 2851 N N   . ASP C 3 194 ? 341.709 326.457 452.505 1.00 98.94  ? 194 ASP A N   1 
ATOM 2852 C CA  . ASP C 3 194 ? 340.841 326.846 453.609 1.00 98.94  ? 194 ASP A CA  1 
ATOM 2853 C C   . ASP C 3 194 ? 339.935 325.667 453.928 1.00 98.94  ? 194 ASP A C   1 
ATOM 2854 O O   . ASP C 3 194 ? 338.817 325.564 453.426 1.00 98.94  ? 194 ASP A O   1 
ATOM 2855 C CB  . ASP C 3 194 ? 340.033 328.086 453.272 1.00 98.94  ? 194 ASP A CB  1 
ATOM 2856 C CG  . ASP C 3 194 ? 339.225 328.572 454.446 1.00 98.94  ? 194 ASP A CG  1 
ATOM 2857 O OD1 . ASP C 3 194 ? 339.643 328.314 455.593 1.00 98.94  ? 194 ASP A OD1 1 
ATOM 2858 O OD2 . ASP C 3 194 ? 338.172 329.205 454.229 1.00 98.94  ? 194 ASP A OD2 1 
ATOM 2859 N N   . GLY C 3 195 ? 340.422 324.778 454.779 1.00 98.19  ? 195 GLY A N   1 
ATOM 2860 C CA  . GLY C 3 195 ? 339.652 323.626 455.193 1.00 98.19  ? 195 GLY A CA  1 
ATOM 2861 C C   . GLY C 3 195 ? 340.502 322.690 456.017 1.00 98.19  ? 195 GLY A C   1 
ATOM 2862 O O   . GLY C 3 195 ? 341.705 322.913 456.158 1.00 98.19  ? 195 GLY A O   1 
ATOM 2863 N N   . TRP C 3 196 ? 339.908 321.642 456.563 1.00 97.02  ? 196 TRP A N   1 
ATOM 2864 C CA  . TRP C 3 196 ? 340.687 320.723 457.368 1.00 97.02  ? 196 TRP A CA  1 
ATOM 2865 C C   . TRP C 3 196 ? 341.283 319.638 456.481 1.00 97.02  ? 196 TRP A C   1 
ATOM 2866 O O   . TRP C 3 196 ? 341.052 319.590 455.273 1.00 97.02  ? 196 TRP A O   1 
ATOM 2867 C CB  . TRP C 3 196 ? 339.827 320.148 458.481 1.00 97.02  ? 196 TRP A CB  1 
ATOM 2868 C CG  . TRP C 3 196 ? 339.732 321.069 459.632 1.00 97.02  ? 196 TRP A CG  1 
ATOM 2869 C CD1 . TRP C 3 196 ? 340.423 320.990 460.799 1.00 97.02  ? 196 TRP A CD1 1 
ATOM 2870 C CD2 . TRP C 3 196 ? 338.915 322.235 459.726 1.00 97.02  ? 196 TRP A CD2 1 
ATOM 2871 N NE1 . TRP C 3 196 ? 340.079 322.028 461.624 1.00 97.02  ? 196 TRP A NE1 1 
ATOM 2872 C CE2 . TRP C 3 196 ? 339.153 322.808 460.986 1.00 97.02  ? 196 TRP A CE2 1 
ATOM 2873 C CE3 . TRP C 3 196 ? 337.998 322.846 458.871 1.00 97.02  ? 196 TRP A CE3 1 
ATOM 2874 C CZ2 . TRP C 3 196 ? 338.513 323.960 461.409 1.00 97.02  ? 196 TRP A CZ2 1 
ATOM 2875 C CZ3 . TRP C 3 196 ? 337.364 323.987 459.291 1.00 97.02  ? 196 TRP A CZ3 1 
ATOM 2876 C CH2 . TRP C 3 196 ? 337.623 324.535 460.549 1.00 97.02  ? 196 TRP A CH2 1 
ATOM 2877 N N   . THR C 3 197 ? 342.072 318.761 457.086 1.00 94.14  ? 197 THR A N   1 
ATOM 2878 C CA  . THR C 3 197 ? 342.747 317.712 456.338 1.00 94.14  ? 197 THR A CA  1 
ATOM 2879 C C   . THR C 3 197 ? 341.788 316.612 455.907 1.00 94.14  ? 197 THR A C   1 
ATOM 2880 O O   . THR C 3 197 ? 342.011 315.942 454.901 1.00 94.14  ? 197 THR A O   1 
ATOM 2881 C CB  . THR C 3 197 ? 343.861 317.087 457.159 1.00 94.14  ? 197 THR A CB  1 
ATOM 2882 O OG1 . THR C 3 197 ? 344.464 316.035 456.402 1.00 94.14  ? 197 THR A OG1 1 
ATOM 2883 C CG2 . THR C 3 197 ? 343.297 316.512 458.438 1.00 94.14  ? 197 THR A CG2 1 
ATOM 2884 N N   . VAL C 3 204 ? 343.217 318.784 461.713 1.00 95.71  ? 204 VAL A N   1 
ATOM 2885 C CA  . VAL C 3 204 ? 344.176 319.879 461.684 1.00 95.71  ? 204 VAL A CA  1 
ATOM 2886 C C   . VAL C 3 204 ? 343.808 320.819 460.528 1.00 95.71  ? 204 VAL A C   1 
ATOM 2887 O O   . VAL C 3 204 ? 343.315 320.384 459.490 1.00 95.71  ? 204 VAL A O   1 
ATOM 2888 C CB  . VAL C 3 204 ? 345.624 319.329 461.602 1.00 95.71  ? 204 VAL A CB  1 
ATOM 2889 C CG1 . VAL C 3 204 ? 345.837 318.527 460.337 1.00 95.71  ? 204 VAL A CG1 1 
ATOM 2890 C CG2 . VAL C 3 204 ? 346.662 320.433 461.745 1.00 95.71  ? 204 VAL A CG2 1 
ATOM 2891 N N   . TYR C 3 205 ? 343.998 322.118 460.736 1.00 93.97  ? 205 TYR A N   1 
ATOM 2892 C CA  . TYR C 3 205 ? 343.497 323.141 459.831 1.00 93.97  ? 205 TYR A CA  1 
ATOM 2893 C C   . TYR C 3 205 ? 344.607 323.658 458.935 1.00 93.97  ? 205 TYR A C   1 
ATOM 2894 O O   . TYR C 3 205 ? 345.692 323.989 459.415 1.00 93.97  ? 205 TYR A O   1 
ATOM 2895 C CB  . TYR C 3 205 ? 342.902 324.301 460.619 1.00 93.97  ? 205 TYR A CB  1 
ATOM 2896 C CG  . TYR C 3 205 ? 342.516 325.485 459.774 1.00 93.97  ? 205 TYR A CG  1 
ATOM 2897 C CD1 . TYR C 3 205 ? 341.474 325.401 458.868 1.00 93.97  ? 205 TYR A CD1 1 
ATOM 2898 C CD2 . TYR C 3 205 ? 343.179 326.694 459.900 1.00 93.97  ? 205 TYR A CD2 1 
ATOM 2899 C CE1 . TYR C 3 205 ? 341.108 326.485 458.103 1.00 93.97  ? 205 TYR A CE1 1 
ATOM 2900 C CE2 . TYR C 3 205 ? 342.818 327.784 459.139 1.00 93.97  ? 205 TYR A CE2 1 
ATOM 2901 C CZ  . TYR C 3 205 ? 341.782 327.673 458.244 1.00 93.97  ? 205 TYR A CZ  1 
ATOM 2902 O OH  . TYR C 3 205 ? 341.419 328.754 457.482 1.00 93.97  ? 205 TYR A OH  1 
ATOM 2903 N N   . GLY C 3 206 ? 344.318 323.749 457.643 1.00 92.62  ? 206 GLY A N   1 
ATOM 2904 C CA  . GLY C 3 206 ? 345.241 324.324 456.690 1.00 92.62  ? 206 GLY A CA  1 
ATOM 2905 C C   . GLY C 3 206 ? 346.496 323.510 456.473 1.00 92.62  ? 206 GLY A C   1 
ATOM 2906 O O   . GLY C 3 206 ? 347.606 324.041 456.556 1.00 92.62  ? 206 GLY A O   1 
ATOM 2907 N N   . ILE C 3 207 ? 346.341 322.220 456.196 1.00 94.82  ? 207 ILE A N   1 
ATOM 2908 C CA  . ILE C 3 207 ? 347.461 321.332 455.918 1.00 94.82  ? 207 ILE A CA  1 
ATOM 2909 C C   . ILE C 3 207 ? 347.441 320.850 454.476 1.00 94.82  ? 207 ILE A C   1 
ATOM 2910 O O   . ILE C 3 207 ? 348.426 321.015 453.748 1.00 94.82  ? 207 ILE A O   1 
ATOM 2911 C CB  . ILE C 3 207 ? 347.496 320.142 456.902 1.00 94.82  ? 207 ILE A CB  1 
ATOM 2912 C CG1 . ILE C 3 207 ? 348.116 320.591 458.222 1.00 94.82  ? 207 ILE A CG1 1 
ATOM 2913 C CG2 . ILE C 3 207 ? 348.311 318.979 456.358 1.00 94.82  ? 207 ILE A CG2 1 
ATOM 2914 C CD1 . ILE C 3 207 ? 349.560 321.030 458.097 1.00 94.82  ? 207 ILE A CD1 1 
ATOM 2915 N N   . ASN C 3 208 ? 346.313 320.276 454.038 1.00 97.21  ? 208 ASN A N   1 
ATOM 2916 C CA  . ASN C 3 208 ? 346.085 319.800 452.671 1.00 97.21  ? 208 ASN A CA  1 
ATOM 2917 C C   . ASN C 3 208 ? 347.133 318.764 452.261 1.00 97.21  ? 208 ASN A C   1 
ATOM 2918 O O   . ASN C 3 208 ? 348.045 319.034 451.491 1.00 97.21  ? 208 ASN A O   1 
ATOM 2919 C CB  . ASN C 3 208 ? 346.030 320.947 451.659 1.00 97.21  ? 208 ASN A CB  1 
ATOM 2920 C CG  . ASN C 3 208 ? 345.585 320.484 450.295 1.00 97.21  ? 208 ASN A CG  1 
ATOM 2921 O OD1 . ASN C 3 208 ? 344.800 319.547 450.175 1.00 97.21  ? 208 ASN A OD1 1 
ATOM 2922 N ND2 . ASN C 3 208 ? 346.093 321.128 449.257 1.00 97.21  ? 208 ASN A ND2 1 
ATOM 2923 N N   . THR C 3 209 ? 347.002 317.582 452.827 1.00 100.96 ? 209 THR A N   1 
ATOM 2924 C CA  . THR C 3 209 ? 347.950 316.487 452.600 1.00 100.96 ? 209 THR A CA  1 
ATOM 2925 C C   . THR C 3 209 ? 348.010 315.977 451.130 1.00 100.96 ? 209 THR A C   1 
ATOM 2926 O O   . THR C 3 209 ? 348.692 314.980 450.895 1.00 100.96 ? 209 THR A O   1 
ATOM 2927 C CB  . THR C 3 209 ? 347.613 315.323 453.526 1.00 100.96 ? 209 THR A CB  1 
ATOM 2928 O OG1 . THR C 3 209 ? 348.427 314.195 453.190 1.00 100.96 ? 209 THR A OG1 1 
ATOM 2929 C CG2 . THR C 3 209 ? 346.161 314.947 453.380 1.00 100.96 ? 209 THR A CG2 1 
ATOM 2930 N N   . LEU C 3 210 ? 347.330 316.579 450.156 1.00 101.75 ? 210 LEU A N   1 
ATOM 2931 C CA  . LEU C 3 210 ? 347.468 316.182 448.764 1.00 101.75 ? 210 LEU A CA  1 
ATOM 2932 C C   . LEU C 3 210 ? 348.829 316.556 448.190 1.00 101.75 ? 210 LEU A C   1 
ATOM 2933 O O   . LEU C 3 210 ? 349.486 315.716 447.571 1.00 101.75 ? 210 LEU A O   1 
ATOM 2934 C CB  . LEU C 3 210 ? 346.355 316.821 447.940 1.00 101.75 ? 210 LEU A CB  1 
ATOM 2935 C CG  . LEU C 3 210 ? 346.213 316.370 446.492 1.00 101.75 ? 210 LEU A CG  1 
ATOM 2936 C CD1 . LEU C 3 210 ? 345.918 314.888 446.434 1.00 101.75 ? 210 LEU A CD1 1 
ATOM 2937 C CD2 . LEU C 3 210 ? 345.116 317.167 445.811 1.00 101.75 ? 210 LEU A CD2 1 
ATOM 2938 N N   . ASN C 3 211 ? 349.274 317.800 448.366 1.00 100.45 ? 211 ASN A N   1 
ATOM 2939 C CA  . ASN C 3 211 ? 350.517 318.243 447.733 1.00 100.45 ? 211 ASN A CA  1 
ATOM 2940 C C   . ASN C 3 211 ? 351.675 318.019 448.696 1.00 100.45 ? 211 ASN A C   1 
ATOM 2941 O O   . ASN C 3 211 ? 352.189 318.945 449.321 1.00 100.45 ? 211 ASN A O   1 
ATOM 2942 C CB  . ASN C 3 211 ? 350.423 319.695 447.281 1.00 100.45 ? 211 ASN A CB  1 
ATOM 2943 C CG  . ASN C 3 211 ? 349.828 320.602 448.326 1.00 100.45 ? 211 ASN A CG  1 
ATOM 2944 O OD1 . ASN C 3 211 ? 349.574 320.186 449.442 1.00 100.45 ? 211 ASN A OD1 1 
ATOM 2945 N ND2 . ASN C 3 211 ? 349.609 321.856 447.967 1.00 100.45 ? 211 ASN A ND2 1 
ATOM 2946 N N   . ASN C 3 212 ? 352.107 316.769 448.797 1.00 98.96  ? 212 ASN A N   1 
ATOM 2947 C CA  . ASN C 3 212 ? 353.269 316.400 449.597 1.00 98.96  ? 212 ASN A CA  1 
ATOM 2948 C C   . ASN C 3 212 ? 354.298 315.805 448.653 1.00 98.96  ? 212 ASN A C   1 
ATOM 2949 O O   . ASN C 3 212 ? 354.020 314.813 447.975 1.00 98.96  ? 212 ASN A O   1 
ATOM 2950 C CB  . ASN C 3 212 ? 352.899 315.412 450.693 1.00 98.96  ? 212 ASN A CB  1 
ATOM 2951 C CG  . ASN C 3 212 ? 354.107 314.852 451.382 1.00 98.96  ? 212 ASN A CG  1 
ATOM 2952 O OD1 . ASN C 3 212 ? 354.345 313.648 451.361 1.00 98.96  ? 212 ASN A OD1 1 
ATOM 2953 N ND2 . ASN C 3 212 ? 354.898 315.727 451.986 1.00 98.96  ? 212 ASN A ND2 1 
ATOM 2954 N N   . MET C 3 213 ? 355.482 316.406 448.606 1.00 93.86  ? 213 MET A N   1 
ATOM 2955 C CA  . MET C 3 213 ? 356.430 316.112 447.545 1.00 93.86  ? 213 MET A CA  1 
ATOM 2956 C C   . MET C 3 213 ? 357.589 315.222 447.969 1.00 93.86  ? 213 MET A C   1 
ATOM 2957 O O   . MET C 3 213 ? 358.465 314.951 447.145 1.00 93.86  ? 213 MET A O   1 
ATOM 2958 C CB  . MET C 3 213 ? 356.975 317.418 446.972 1.00 93.86  ? 213 MET A CB  1 
ATOM 2959 C CG  . MET C 3 213 ? 355.907 318.249 446.297 1.00 93.86  ? 213 MET A CG  1 
ATOM 2960 S SD  . MET C 3 213 ? 356.515 319.789 445.586 1.00 93.86  ? 213 MET A SD  1 
ATOM 2961 C CE  . MET C 3 213 ? 356.710 320.794 447.053 1.00 93.86  ? 213 MET A CE  1 
ATOM 2962 N N   . GLY C 3 214 ? 357.632 314.770 449.212 1.00 83.72  ? 214 GLY A N   1 
ATOM 2963 C CA  . GLY C 3 214 ? 358.628 313.814 449.647 1.00 83.72  ? 214 GLY A CA  1 
ATOM 2964 C C   . GLY C 3 214 ? 359.837 314.488 450.261 1.00 83.72  ? 214 GLY A C   1 
ATOM 2965 O O   . GLY C 3 214 ? 359.928 315.710 450.347 1.00 83.72  ? 214 GLY A O   1 
ATOM 2966 N N   . THR C 3 215 ? 360.782 313.654 450.684 1.00 83.24  ? 215 THR A N   1 
ATOM 2967 C CA  . THR C 3 215 ? 361.944 314.098 451.437 1.00 83.24  ? 215 THR A CA  1 
ATOM 2968 C C   . THR C 3 215 ? 363.234 313.665 450.755 1.00 83.24  ? 215 THR A C   1 
ATOM 2969 O O   . THR C 3 215 ? 363.224 312.913 449.780 1.00 83.24  ? 215 THR A O   1 
ATOM 2970 C CB  . THR C 3 215 ? 361.923 313.538 452.856 1.00 83.24  ? 215 THR A CB  1 
ATOM 2971 O OG1 . THR C 3 215 ? 361.711 312.126 452.798 1.00 83.24  ? 215 THR A OG1 1 
ATOM 2972 C CG2 . THR C 3 215 ? 360.809 314.166 453.654 1.00 83.24  ? 215 THR A CG2 1 
ATOM 2973 N N   . LEU C 3 216 ? 364.351 314.145 451.293 1.00 80.36  ? 216 LEU A N   1 
ATOM 2974 C CA  . LEU C 3 216 ? 365.680 313.806 450.811 1.00 80.36  ? 216 LEU A CA  1 
ATOM 2975 C C   . LEU C 3 216 ? 366.542 313.341 451.972 1.00 80.36  ? 216 LEU A C   1 
ATOM 2976 O O   . LEU C 3 216 ? 366.310 313.715 453.122 1.00 80.36  ? 216 LEU A O   1 
ATOM 2977 C CB  . LEU C 3 216 ? 366.346 314.991 450.145 1.00 80.36  ? 216 LEU A CB  1 
ATOM 2978 C CG  . LEU C 3 216 ? 365.664 315.530 448.906 1.00 80.36  ? 216 LEU A CG  1 
ATOM 2979 C CD1 . LEU C 3 216 ? 366.513 316.624 448.351 1.00 80.36  ? 216 LEU A CD1 1 
ATOM 2980 C CD2 . LEU C 3 216 ? 365.513 314.437 447.901 1.00 80.36  ? 216 LEU A CD2 1 
ATOM 2981 N N   . TYR C 3 217 ? 367.543 312.521 451.670 1.00 85.87  ? 217 TYR A N   1 
ATOM 2982 C CA  . TYR C 3 217 ? 368.391 311.940 452.698 1.00 85.87  ? 217 TYR A CA  1 
ATOM 2983 C C   . TYR C 3 217 ? 369.804 311.772 452.173 1.00 85.87  ? 217 TYR A C   1 
ATOM 2984 O O   . TYR C 3 217 ? 370.006 311.218 451.092 1.00 85.87  ? 217 TYR A O   1 
ATOM 2985 C CB  . TYR C 3 217 ? 367.845 310.593 453.155 1.00 85.87  ? 217 TYR A CB  1 
ATOM 2986 C CG  . TYR C 3 217 ? 366.615 310.736 453.990 1.00 85.87  ? 217 TYR A CG  1 
ATOM 2987 C CD1 . TYR C 3 217 ? 366.709 311.122 455.306 1.00 85.87  ? 217 TYR A CD1 1 
ATOM 2988 C CD2 . TYR C 3 217 ? 365.360 310.522 453.455 1.00 85.87  ? 217 TYR A CD2 1 
ATOM 2989 C CE1 . TYR C 3 217 ? 365.601 311.264 456.072 1.00 85.87  ? 217 TYR A CE1 1 
ATOM 2990 C CE2 . TYR C 3 217 ? 364.235 310.673 454.219 1.00 85.87  ? 217 TYR A CE2 1 
ATOM 2991 C CZ  . TYR C 3 217 ? 364.365 311.047 455.529 1.00 85.87  ? 217 TYR A CZ  1 
ATOM 2992 O OH  . TYR C 3 217 ? 363.254 311.205 456.312 1.00 85.87  ? 217 TYR A OH  1 
ATOM 2993 N N   . MET C 3 218 ? 370.779 312.247 452.942 1.00 87.84  ? 218 MET A N   1 
ATOM 2994 C CA  . MET C 3 218 ? 372.173 312.240 452.529 1.00 87.84  ? 218 MET A CA  1 
ATOM 2995 C C   . MET C 3 218 ? 373.037 311.635 453.621 1.00 87.84  ? 218 MET A C   1 
ATOM 2996 O O   . MET C 3 218 ? 372.820 311.900 454.804 1.00 87.84  ? 218 MET A O   1 
ATOM 2997 C CB  . MET C 3 218 ? 372.660 313.649 452.226 1.00 87.84  ? 218 MET A CB  1 
ATOM 2998 C CG  . MET C 3 218 ? 372.105 314.225 450.954 1.00 87.84  ? 218 MET A CG  1 
ATOM 2999 S SD  . MET C 3 218 ? 370.515 315.020 451.208 1.00 87.84  ? 218 MET A SD  1 
ATOM 3000 C CE  . MET C 3 218 ? 371.033 316.690 451.557 1.00 87.84  ? 218 MET A CE  1 
ATOM 3001 N N   . ARG C 3 219 ? 374.026 310.843 453.217 1.00 85.09  ? 219 ARG A N   1 
ATOM 3002 C CA  . ARG C 3 219 ? 374.991 310.265 454.141 1.00 85.09  ? 219 ARG A CA  1 
ATOM 3003 C C   . ARG C 3 219 ? 376.208 309.830 453.349 1.00 85.09  ? 219 ARG A C   1 
ATOM 3004 O O   . ARG C 3 219 ? 376.153 309.693 452.126 1.00 85.09  ? 219 ARG A O   1 
ATOM 3005 C CB  . ARG C 3 219 ? 374.414 309.069 454.898 1.00 85.09  ? 219 ARG A CB  1 
ATOM 3006 C CG  . ARG C 3 219 ? 374.163 307.861 454.021 1.00 85.09  ? 219 ARG A CG  1 
ATOM 3007 C CD  . ARG C 3 219 ? 373.509 306.729 454.787 1.00 85.09  ? 219 ARG A CD  1 
ATOM 3008 N NE  . ARG C 3 219 ? 373.205 305.597 453.922 1.00 85.09  ? 219 ARG A NE  1 
ATOM 3009 C CZ  . ARG C 3 219 ? 373.867 304.449 453.939 1.00 85.09  ? 219 ARG A CZ  1 
ATOM 3010 N NH1 . ARG C 3 219 ? 374.872 304.277 454.780 1.00 85.09  ? 219 ARG A NH1 1 
ATOM 3011 N NH2 . ARG C 3 219 ? 373.524 303.471 453.119 1.00 85.09  ? 219 ARG A NH2 1 
ATOM 3012 N N   . HIS C 3 220 ? 377.309 309.607 454.057 1.00 88.08  ? 220 HIS A N   1 
ATOM 3013 C CA  . HIS C 3 220 ? 378.468 309.012 453.416 1.00 88.08  ? 220 HIS A CA  1 
ATOM 3014 C C   . HIS C 3 220 ? 378.260 307.516 453.240 1.00 88.08  ? 220 HIS A C   1 
ATOM 3015 O O   . HIS C 3 220 ? 377.321 306.927 453.773 1.00 88.08  ? 220 HIS A O   1 
ATOM 3016 C CB  . HIS C 3 220 ? 379.732 309.235 454.234 1.00 88.08  ? 220 HIS A CB  1 
ATOM 3017 C CG  . HIS C 3 220 ? 380.022 310.667 454.525 1.00 88.08  ? 220 HIS A CG  1 
ATOM 3018 N ND1 . HIS C 3 220 ? 379.510 311.317 455.623 1.00 88.08  ? 220 HIS A ND1 1 
ATOM 3019 C CD2 . HIS C 3 220 ? 380.786 311.570 453.872 1.00 88.08  ? 220 HIS A CD2 1 
ATOM 3020 C CE1 . HIS C 3 220 ? 379.946 312.563 455.634 1.00 88.08  ? 220 HIS A CE1 1 
ATOM 3021 N NE2 . HIS C 3 220 ? 380.718 312.743 454.579 1.00 88.08  ? 220 HIS A NE2 1 
ATOM 3022 N N   . VAL C 3 221 ? 379.158 306.894 452.486 1.00 87.84  ? 221 VAL A N   1 
ATOM 3023 C CA  . VAL C 3 221 ? 379.171 305.441 452.422 1.00 87.84  ? 221 VAL A CA  1 
ATOM 3024 C C   . VAL C 3 221 ? 380.556 304.952 452.812 1.00 87.84  ? 221 VAL A C   1 
ATOM 3025 O O   . VAL C 3 221 ? 380.772 303.751 452.996 1.00 87.84  ? 221 VAL A O   1 
ATOM 3026 C CB  . VAL C 3 221 ? 378.785 304.922 451.030 1.00 87.84  ? 221 VAL A CB  1 
ATOM 3027 C CG1 . VAL C 3 221 ? 377.364 305.285 450.698 1.00 87.84  ? 221 VAL A CG1 1 
ATOM 3028 C CG2 . VAL C 3 221 ? 379.714 305.472 450.010 1.00 87.84  ? 221 VAL A CG2 1 
ATOM 3029 N N   . ASN C 3 222 ? 381.499 305.874 452.947 1.00 95.62  ? 222 ASN A N   1 
ATOM 3030 C CA  . ASN C 3 222 ? 382.862 305.538 453.328 1.00 95.62  ? 222 ASN A CA  1 
ATOM 3031 C C   . ASN C 3 222 ? 382.983 305.543 454.841 1.00 95.62  ? 222 ASN A C   1 
ATOM 3032 O O   . ASN C 3 222 ? 382.824 306.588 455.476 1.00 95.62  ? 222 ASN A O   1 
ATOM 3033 C CB  . ASN C 3 222 ? 383.856 306.526 452.730 1.00 95.62  ? 222 ASN A CB  1 
ATOM 3034 C CG  . ASN C 3 222 ? 383.928 306.433 451.236 1.00 95.62  ? 222 ASN A CG  1 
ATOM 3035 O OD1 . ASN C 3 222 ? 383.855 307.440 450.538 1.00 95.62  ? 222 ASN A OD1 1 
ATOM 3036 N ND2 . ASN C 3 222 ? 384.068 305.217 450.728 1.00 95.62  ? 222 ASN A ND2 1 
ATOM 3037 N N   . GLU C 3 223 ? 383.269 304.382 455.409 1.00 105.07 ? 223 GLU A N   1 
ATOM 3038 C CA  . GLU C 3 223 ? 383.475 304.252 456.841 1.00 105.07 ? 223 GLU A CA  1 
ATOM 3039 C C   . GLU C 3 223 ? 384.781 304.928 457.231 1.00 105.07 ? 223 GLU A C   1 
ATOM 3040 O O   . GLU C 3 223 ? 385.766 304.871 456.492 1.00 105.07 ? 223 GLU A O   1 
ATOM 3041 C CB  . GLU C 3 223 ? 383.486 302.776 457.242 1.00 105.07 ? 223 GLU A CB  1 
ATOM 3042 C CG  . GLU C 3 223 ? 384.429 301.887 456.429 1.00 105.07 ? 223 GLU A CG  1 
ATOM 3043 C CD  . GLU C 3 223 ? 383.801 301.305 455.170 1.00 105.07 ? 223 GLU A CD  1 
ATOM 3044 O OE1 . GLU C 3 223 ? 383.005 302.006 454.511 1.00 105.07 ? 223 GLU A OE1 1 
ATOM 3045 O OE2 . GLU C 3 223 ? 384.107 300.145 454.835 1.00 105.07 ? 223 GLU A OE2 1 
ATOM 3046 N N   . ALA C 3 224 ? 384.773 305.599 458.378 1.00 112.07 ? 224 ALA A N   1 
ATOM 3047 C CA  . ALA C 3 224 ? 385.923 306.385 458.799 1.00 112.07 ? 224 ALA A CA  1 
ATOM 3048 C C   . ALA C 3 224 ? 387.067 305.477 459.215 1.00 112.07 ? 224 ALA A C   1 
ATOM 3049 O O   . ALA C 3 224 ? 386.872 304.512 459.954 1.00 112.07 ? 224 ALA A O   1 
ATOM 3050 C CB  . ALA C 3 224 ? 385.550 307.303 459.960 1.00 112.07 ? 224 ALA A CB  1 
ATOM 3051 N N   . GLY C 3 225 ? 388.261 305.778 458.720 1.00 120.44 ? 225 GLY A N   1 
ATOM 3052 C CA  . GLY C 3 225 ? 389.405 304.980 459.103 1.00 120.44 ? 225 GLY A CA  1 
ATOM 3053 C C   . GLY C 3 225 ? 390.327 305.631 460.112 1.00 120.44 ? 225 GLY A C   1 
ATOM 3054 O O   . GLY C 3 225 ? 390.719 304.998 461.095 1.00 120.44 ? 225 GLY A O   1 
ATOM 3055 N N   . GLN C 3 226 ? 390.677 306.896 459.892 1.00 128.46 ? 226 GLN A N   1 
ATOM 3056 C CA  . GLN C 3 226 ? 391.605 307.588 460.775 1.00 128.46 ? 226 GLN A CA  1 
ATOM 3057 C C   . GLN C 3 226 ? 391.173 308.988 461.173 1.00 128.46 ? 226 GLN A C   1 
ATOM 3058 O O   . GLN C 3 226 ? 391.534 309.427 462.270 1.00 128.46 ? 226 GLN A O   1 
ATOM 3059 C CB  . GLN C 3 226 ? 392.995 307.679 460.130 1.00 128.46 ? 226 GLN A CB  1 
ATOM 3060 C CG  . GLN C 3 226 ? 393.750 306.367 460.093 1.00 128.46 ? 226 GLN A CG  1 
ATOM 3061 C CD  . GLN C 3 226 ? 393.989 305.800 461.472 1.00 128.46 ? 226 GLN A CD  1 
ATOM 3062 O OE1 . GLN C 3 226 ? 393.508 304.720 461.805 1.00 128.46 ? 226 GLN A OE1 1 
ATOM 3063 N NE2 . GLN C 3 226 ? 394.744 306.525 462.282 1.00 128.46 ? 226 GLN A NE2 1 
ATOM 3064 N N   . GLY C 3 227 ? 390.417 309.696 460.345 1.00 116.51 ? 227 GLY A N   1 
ATOM 3065 C CA  . GLY C 3 227 ? 390.055 311.059 460.643 1.00 116.51 ? 227 GLY A CA  1 
ATOM 3066 C C   . GLY C 3 227 ? 388.623 311.354 460.266 1.00 116.51 ? 227 GLY A C   1 
ATOM 3067 O O   . GLY C 3 227 ? 388.184 311.061 459.151 1.00 116.51 ? 227 GLY A O   1 
ATOM 3068 N N   . PRO C 3 228 ? 387.862 311.925 461.196 1.00 105.97 ? 228 PRO A N   1 
ATOM 3069 C CA  . PRO C 3 228 ? 386.460 312.232 460.911 1.00 105.97 ? 228 PRO A CA  1 
ATOM 3070 C C   . PRO C 3 228 ? 386.347 313.357 459.902 1.00 105.97 ? 228 PRO A C   1 
ATOM 3071 O O   . PRO C 3 228 ? 387.205 314.237 459.821 1.00 105.97 ? 228 PRO A O   1 
ATOM 3072 C CB  . PRO C 3 228 ? 385.901 312.655 462.275 1.00 105.97 ? 228 PRO A CB  1 
ATOM 3073 C CG  . PRO C 3 228 ? 386.916 312.214 463.273 1.00 105.97 ? 228 PRO A CG  1 
ATOM 3074 C CD  . PRO C 3 228 ? 388.225 312.279 462.574 1.00 105.97 ? 228 PRO A CD  1 
ATOM 3075 N N   . ILE C 3 229 ? 385.287 313.303 459.105 1.00 98.15  ? 229 ILE A N   1 
ATOM 3076 C CA  . ILE C 3 229 ? 385.048 314.301 458.072 1.00 98.15  ? 229 ILE A CA  1 
ATOM 3077 C C   . ILE C 3 229 ? 383.593 314.725 458.162 1.00 98.15  ? 229 ILE A C   1 
ATOM 3078 O O   . ILE C 3 229 ? 382.695 313.878 458.121 1.00 98.15  ? 229 ILE A O   1 
ATOM 3079 C CB  . ILE C 3 229 ? 385.376 313.768 456.668 1.00 98.15  ? 229 ILE A CB  1 
ATOM 3080 C CG1 . ILE C 3 229 ? 386.884 313.805 456.438 1.00 98.15  ? 229 ILE A CG1 1 
ATOM 3081 C CG2 . ILE C 3 229 ? 384.678 314.579 455.594 1.00 98.15  ? 229 ILE A CG2 1 
ATOM 3082 C CD1 . ILE C 3 229 ? 387.304 313.422 455.042 1.00 98.15  ? 229 ILE A CD1 1 
ATOM 3083 N N   . LYS C 3 230 ? 383.356 316.021 458.317 1.00 89.84  ? 230 LYS A N   1 
ATOM 3084 C CA  . LYS C 3 230 ? 382.021 316.574 458.208 1.00 89.84  ? 230 LYS A CA  1 
ATOM 3085 C C   . LYS C 3 230 ? 381.900 317.288 456.874 1.00 89.84  ? 230 LYS A C   1 
ATOM 3086 O O   . LYS C 3 230 ? 382.893 317.733 456.297 1.00 89.84  ? 230 LYS A O   1 
ATOM 3087 C CB  . LYS C 3 230 ? 381.712 317.523 459.364 1.00 89.84  ? 230 LYS A CB  1 
ATOM 3088 C CG  . LYS C 3 230 ? 382.367 318.882 459.283 1.00 89.84  ? 230 LYS A CG  1 
ATOM 3089 C CD  . LYS C 3 230 ? 382.171 319.655 460.572 1.00 89.84  ? 230 LYS A CD  1 
ATOM 3090 C CE  . LYS C 3 230 ? 380.708 319.731 460.963 1.00 89.84  ? 230 LYS A CE  1 
ATOM 3091 N NZ  . LYS C 3 230 ? 380.537 320.111 462.388 1.00 89.84  ? 230 LYS A NZ  1 
ATOM 3092 N N   . SER C 3 231 ? 380.680 317.356 456.364 1.00 84.81  ? 231 SER A N   1 
ATOM 3093 C CA  . SER C 3 231 ? 380.449 317.869 455.027 1.00 84.81  ? 231 SER A CA  1 
ATOM 3094 C C   . SER C 3 231 ? 379.145 318.640 455.007 1.00 84.81  ? 231 SER A C   1 
ATOM 3095 O O   . SER C 3 231 ? 378.191 318.288 455.698 1.00 84.81  ? 231 SER A O   1 
ATOM 3096 C CB  . SER C 3 231 ? 380.388 316.746 453.998 1.00 84.81  ? 231 SER A CB  1 
ATOM 3097 O OG  . SER C 3 231 ? 381.422 315.803 454.204 1.00 84.81  ? 231 SER A OG  1 
ATOM 3098 N N   . THR C 3 232 ? 379.111 319.689 454.205 1.00 83.02  ? 232 THR A N   1 
ATOM 3099 C CA  . THR C 3 232 ? 377.916 320.495 454.050 1.00 83.02  ? 232 THR A CA  1 
ATOM 3100 C C   . THR C 3 232 ? 377.281 320.188 452.706 1.00 83.02  ? 232 THR A C   1 
ATOM 3101 O O   . THR C 3 232 ? 377.850 319.485 451.872 1.00 83.02  ? 232 THR A O   1 
ATOM 3102 C CB  . THR C 3 232 ? 378.238 321.985 454.150 1.00 83.02  ? 232 THR A CB  1 
ATOM 3103 O OG1 . THR C 3 232 ? 378.943 322.393 452.976 1.00 83.02  ? 232 THR A OG1 1 
ATOM 3104 C CG2 . THR C 3 232 ? 379.113 322.252 455.348 1.00 83.02  ? 232 THR A CG2 1 
ATOM 3105 N N   . VAL C 3 233 ? 376.093 320.736 452.503 1.00 81.86  ? 233 VAL A N   1 
ATOM 3106 C CA  . VAL C 3 233 ? 375.344 320.537 451.271 1.00 81.86  ? 233 VAL A CA  1 
ATOM 3107 C C   . VAL C 3 233 ? 374.392 321.712 451.107 1.00 81.86  ? 233 VAL A C   1 
ATOM 3108 O O   . VAL C 3 233 ? 373.804 322.187 452.082 1.00 81.86  ? 233 VAL A O   1 
ATOM 3109 C CB  . VAL C 3 233 ? 374.627 319.171 451.282 1.00 81.86  ? 233 VAL A CB  1 
ATOM 3110 C CG1 . VAL C 3 233 ? 373.768 319.016 452.507 1.00 81.86  ? 233 VAL A CG1 1 
ATOM 3111 C CG2 . VAL C 3 233 ? 373.805 318.972 450.035 1.00 81.86  ? 233 VAL A CG2 1 
ATOM 3112 N N   . ARG C 3 234 ? 374.302 322.242 449.894 1.00 85.80  ? 234 ARG A N   1 
ATOM 3113 C CA  . ARG C 3 234 ? 373.434 323.376 449.599 1.00 85.80  ? 234 ARG A CA  1 
ATOM 3114 C C   . ARG C 3 234 ? 372.499 322.959 448.477 1.00 85.80  ? 234 ARG A C   1 
ATOM 3115 O O   . ARG C 3 234 ? 372.877 322.993 447.306 1.00 85.80  ? 234 ARG A O   1 
ATOM 3116 C CB  . ARG C 3 234 ? 374.244 324.604 449.213 1.00 85.80  ? 234 ARG A CB  1 
ATOM 3117 C CG  . ARG C 3 234 ? 375.345 324.949 450.186 1.00 85.80  ? 234 ARG A CG  1 
ATOM 3118 C CD  . ARG C 3 234 ? 376.161 326.125 449.707 1.00 85.80  ? 234 ARG A CD  1 
ATOM 3119 N NE  . ARG C 3 234 ? 377.311 326.330 450.569 1.00 85.80  ? 234 ARG A NE  1 
ATOM 3120 C CZ  . ARG C 3 234 ? 377.281 327.059 451.675 1.00 85.80  ? 234 ARG A CZ  1 
ATOM 3121 N NH1 . ARG C 3 234 ? 376.158 327.658 452.039 1.00 85.80  ? 234 ARG A NH1 1 
ATOM 3122 N NH2 . ARG C 3 234 ? 378.370 327.191 452.417 1.00 85.80  ? 234 ARG A NH2 1 
ATOM 3123 N N   . ILE C 3 235 ? 371.282 322.583 448.836 1.00 80.39  ? 235 ILE A N   1 
ATOM 3124 C CA  . ILE C 3 235 ? 370.325 322.068 447.868 1.00 80.39  ? 235 ILE A CA  1 
ATOM 3125 C C   . ILE C 3 235 ? 369.762 323.220 447.056 1.00 80.39  ? 235 ILE A C   1 
ATOM 3126 O O   . ILE C 3 235 ? 369.247 324.192 447.615 1.00 80.39  ? 235 ILE A O   1 
ATOM 3127 C CB  . ILE C 3 235 ? 369.208 321.302 448.579 1.00 80.39  ? 235 ILE A CB  1 
ATOM 3128 C CG1 . ILE C 3 235 ? 369.815 320.215 449.450 1.00 80.39  ? 235 ILE A CG1 1 
ATOM 3129 C CG2 . ILE C 3 235 ? 368.267 320.704 447.577 1.00 80.39  ? 235 ILE A CG2 1 
ATOM 3130 C CD1 . ILE C 3 235 ? 368.816 319.510 450.308 1.00 80.39  ? 235 ILE A CD1 1 
ATOM 3131 N N   . TYR C 3 236 ? 369.850 323.114 445.739 1.00 80.86  ? 236 TYR A N   1 
ATOM 3132 C CA  . TYR C 3 236 ? 369.314 324.133 444.856 1.00 80.86  ? 236 TYR A CA  1 
ATOM 3133 C C   . TYR C 3 236 ? 367.988 323.661 444.288 1.00 80.86  ? 236 TYR A C   1 
ATOM 3134 O O   . TYR C 3 236 ? 367.560 322.531 444.515 1.00 80.86  ? 236 TYR A O   1 
ATOM 3135 C CB  . TYR C 3 236 ? 370.296 324.469 443.740 1.00 80.86  ? 236 TYR A CB  1 
ATOM 3136 C CG  . TYR C 3 236 ? 371.263 325.546 444.137 1.00 80.86  ? 236 TYR A CG  1 
ATOM 3137 C CD1 . TYR C 3 236 ? 372.032 325.421 445.280 1.00 80.86  ? 236 TYR A CD1 1 
ATOM 3138 C CD2 . TYR C 3 236 ? 371.407 326.687 443.376 1.00 80.86  ? 236 TYR A CD2 1 
ATOM 3139 C CE1 . TYR C 3 236 ? 372.912 326.399 445.655 1.00 80.86  ? 236 TYR A CE1 1 
ATOM 3140 C CE2 . TYR C 3 236 ? 372.291 327.675 443.743 1.00 80.86  ? 236 TYR A CE2 1 
ATOM 3141 C CZ  . TYR C 3 236 ? 373.040 327.524 444.885 1.00 80.86  ? 236 TYR A CZ  1 
ATOM 3142 O OH  . TYR C 3 236 ? 373.923 328.502 445.263 1.00 80.86  ? 236 TYR A OH  1 
ATOM 3143 N N   . PHE C 3 237 ? 367.337 324.543 443.544 1.00 82.33  ? 237 PHE A N   1 
ATOM 3144 C CA  . PHE C 3 237 ? 365.908 324.416 443.318 1.00 82.33  ? 237 PHE A CA  1 
ATOM 3145 C C   . PHE C 3 237 ? 365.518 325.214 442.090 1.00 82.33  ? 237 PHE A C   1 
ATOM 3146 O O   . PHE C 3 237 ? 365.858 326.393 441.993 1.00 82.33  ? 237 PHE A O   1 
ATOM 3147 C CB  . PHE C 3 237 ? 365.163 324.925 444.547 1.00 82.33  ? 237 PHE A CB  1 
ATOM 3148 C CG  . PHE C 3 237 ? 363.720 324.592 444.567 1.00 82.33  ? 237 PHE A CG  1 
ATOM 3149 C CD1 . PHE C 3 237 ? 363.290 323.372 445.043 1.00 82.33  ? 237 PHE A CD1 1 
ATOM 3150 C CD2 . PHE C 3 237 ? 362.786 325.512 444.140 1.00 82.33  ? 237 PHE A CD2 1 
ATOM 3151 C CE1 . PHE C 3 237 ? 361.954 323.068 445.073 1.00 82.33  ? 237 PHE A CE1 1 
ATOM 3152 C CE2 . PHE C 3 237 ? 361.451 325.215 444.168 1.00 82.33  ? 237 PHE A CE2 1 
ATOM 3153 C CZ  . PHE C 3 237 ? 361.033 323.995 444.641 1.00 82.33  ? 237 PHE A CZ  1 
ATOM 3154 N N   . LYS C 3 238 ? 364.803 324.590 441.167 1.00 86.29  ? 238 LYS A N   1 
ATOM 3155 C CA  . LYS C 3 238 ? 364.460 325.286 439.935 1.00 86.29  ? 238 LYS A CA  1 
ATOM 3156 C C   . LYS C 3 238 ? 363.184 324.735 439.320 1.00 86.29  ? 238 LYS A C   1 
ATOM 3157 O O   . LYS C 3 238 ? 363.183 323.619 438.792 1.00 86.29  ? 238 LYS A O   1 
ATOM 3158 C CB  . LYS C 3 238 ? 365.607 325.178 438.936 1.00 86.29  ? 238 LYS A CB  1 
ATOM 3159 C CG  . LYS C 3 238 ? 365.348 325.833 437.598 1.00 86.29  ? 238 LYS A CG  1 
ATOM 3160 C CD  . LYS C 3 238 ? 366.578 325.719 436.721 1.00 86.29  ? 238 LYS A CD  1 
ATOM 3161 C CE  . LYS C 3 238 ? 366.521 326.662 435.541 1.00 86.29  ? 238 LYS A CE  1 
ATOM 3162 N NZ  . LYS C 3 238 ? 365.452 326.280 434.590 1.00 86.29  ? 238 LYS A NZ  1 
ATOM 3163 N N   . PRO C 3 239 ? 362.085 325.475 439.368 1.00 81.21  ? 239 PRO A N   1 
ATOM 3164 C CA  . PRO C 3 239 ? 360.872 325.036 438.682 1.00 81.21  ? 239 PRO A CA  1 
ATOM 3165 C C   . PRO C 3 239 ? 361.019 325.159 437.178 1.00 81.21  ? 239 PRO A C   1 
ATOM 3166 O O   . PRO C 3 239 ? 361.738 326.015 436.665 1.00 81.21  ? 239 PRO A O   1 
ATOM 3167 C CB  . PRO C 3 239 ? 359.803 325.995 439.206 1.00 81.21  ? 239 PRO A CB  1 
ATOM 3168 C CG  . PRO C 3 239 ? 360.381 326.575 440.436 1.00 81.21  ? 239 PRO A CG  1 
ATOM 3169 C CD  . PRO C 3 239 ? 361.839 326.653 440.203 1.00 81.21  ? 239 PRO A CD  1 
ATOM 3170 N N   . LYS C 3 240 ? 360.323 324.280 436.467 1.00 87.87  ? 240 LYS A N   1 
ATOM 3171 C CA  . LYS C 3 240 ? 360.326 324.312 435.014 1.00 87.87  ? 240 LYS A CA  1 
ATOM 3172 C C   . LYS C 3 240 ? 358.927 324.011 434.513 1.00 87.87  ? 240 LYS A C   1 
ATOM 3173 O O   . LYS C 3 240 ? 358.200 323.237 435.140 1.00 87.87  ? 240 LYS A O   1 
ATOM 3174 C CB  . LYS C 3 240 ? 361.310 323.304 434.423 1.00 87.87  ? 240 LYS A CB  1 
ATOM 3175 C CG  . LYS C 3 240 ? 362.750 323.765 434.450 1.00 87.87  ? 240 LYS A CG  1 
ATOM 3176 C CD  . LYS C 3 240 ? 363.574 323.166 433.324 1.00 87.87  ? 240 LYS A CD  1 
ATOM 3177 C CE  . LYS C 3 240 ? 363.361 321.678 433.193 1.00 87.87  ? 240 LYS A CE  1 
ATOM 3178 N NZ  . LYS C 3 240 ? 364.231 321.109 432.136 1.00 87.87  ? 240 LYS A NZ  1 
ATOM 3179 N N   . HIS C 3 241 ? 358.573 324.629 433.383 1.00 89.99  ? 241 HIS A N   1 
ATOM 3180 C CA  . HIS C 3 241 ? 357.289 324.467 432.695 1.00 89.99  ? 241 HIS A CA  1 
ATOM 3181 C C   . HIS C 3 241 ? 356.118 324.805 433.614 1.00 89.99  ? 241 HIS A C   1 
ATOM 3182 O O   . HIS C 3 241 ? 355.240 323.987 433.881 1.00 89.99  ? 241 HIS A O   1 
ATOM 3183 C CB  . HIS C 3 241 ? 357.149 323.058 432.116 1.00 89.99  ? 241 HIS A CB  1 
ATOM 3184 C CG  . HIS C 3 241 ? 358.375 322.577 431.408 1.00 89.99  ? 241 HIS A CG  1 
ATOM 3185 N ND1 . HIS C 3 241 ? 359.066 321.452 431.800 1.00 89.99  ? 241 HIS A ND1 1 
ATOM 3186 C CD2 . HIS C 3 241 ? 359.030 323.064 430.329 1.00 89.99  ? 241 HIS A CD2 1 
ATOM 3187 C CE1 . HIS C 3 241 ? 360.097 321.271 430.996 1.00 89.99  ? 241 HIS A CE1 1 
ATOM 3188 N NE2 . HIS C 3 241 ? 360.098 322.235 430.095 1.00 89.99  ? 241 HIS A NE2 1 
ATOM 3189 N N   . VAL C 3 242 ? 356.124 326.034 434.094 1.00 87.48  ? 242 VAL A N   1 
ATOM 3190 C CA  . VAL C 3 242 ? 355.188 326.458 435.123 1.00 87.48  ? 242 VAL A CA  1 
ATOM 3191 C C   . VAL C 3 242 ? 353.900 326.946 434.483 1.00 87.48  ? 242 VAL A C   1 
ATOM 3192 O O   . VAL C 3 242 ? 353.920 327.642 433.464 1.00 87.48  ? 242 VAL A O   1 
ATOM 3193 C CB  . VAL C 3 242 ? 355.825 327.550 435.992 1.00 87.48  ? 242 VAL A CB  1 
ATOM 3194 C CG1 . VAL C 3 242 ? 355.032 327.753 437.249 1.00 87.48  ? 242 VAL A CG1 1 
ATOM 3195 C CG2 . VAL C 3 242 ? 357.235 327.163 436.327 1.00 87.48  ? 242 VAL A CG2 1 
ATOM 3196 N N   . LYS C 3 243 ? 352.773 326.565 435.072 1.00 89.53  ? 243 LYS A N   1 
ATOM 3197 C CA  . LYS C 3 243 ? 351.465 327.081 434.707 1.00 89.53  ? 243 LYS A CA  1 
ATOM 3198 C C   . LYS C 3 243 ? 350.784 327.591 435.963 1.00 89.53  ? 243 LYS A C   1 
ATOM 3199 O O   . LYS C 3 243 ? 350.768 326.904 436.985 1.00 89.53  ? 243 LYS A O   1 
ATOM 3200 C CB  . LYS C 3 243 ? 350.613 326.011 434.046 1.00 89.53  ? 243 LYS A CB  1 
ATOM 3201 C CG  . LYS C 3 243 ? 351.236 325.447 432.797 1.00 89.53  ? 243 LYS A CG  1 
ATOM 3202 C CD  . LYS C 3 243 ? 350.482 324.249 432.285 1.00 89.53  ? 243 LYS A CD  1 
ATOM 3203 C CE  . LYS C 3 243 ? 351.129 323.742 431.021 1.00 89.53  ? 243 LYS A CE  1 
ATOM 3204 N NZ  . LYS C 3 243 ? 351.198 324.819 430.007 1.00 89.53  ? 243 LYS A NZ  1 
ATOM 3205 N N   . ALA C 3 244 ? 350.226 328.792 435.891 1.00 92.48  ? 244 ALA A N   1 
ATOM 3206 C CA  . ALA C 3 244 ? 349.650 329.431 437.060 1.00 92.48  ? 244 ALA A CA  1 
ATOM 3207 C C   . ALA C 3 244 ? 348.156 329.642 436.880 1.00 92.48  ? 244 ALA A C   1 
ATOM 3208 O O   . ALA C 3 244 ? 347.637 329.658 435.763 1.00 92.48  ? 244 ALA A O   1 
ATOM 3209 C CB  . ALA C 3 244 ? 350.324 330.771 437.351 1.00 92.48  ? 244 ALA A CB  1 
ATOM 3210 N N   . TRP C 3 245 ? 347.470 329.819 438.004 1.00 90.13  ? 245 TRP A N   1 
ATOM 3211 C CA  . TRP C 3 245 ? 346.028 329.980 438.012 1.00 90.13  ? 245 TRP A CA  1 
ATOM 3212 C C   . TRP C 3 245 ? 345.634 330.824 439.212 1.00 90.13  ? 245 TRP A C   1 
ATOM 3213 O O   . TRP C 3 245 ? 346.250 330.719 440.274 1.00 90.13  ? 245 TRP A O   1 
ATOM 3214 C CB  . TRP C 3 245 ? 345.323 328.624 438.077 1.00 90.13  ? 245 TRP A CB  1 
ATOM 3215 C CG  . TRP C 3 245 ? 345.301 327.884 436.790 1.00 90.13  ? 245 TRP A CG  1 
ATOM 3216 C CD1 . TRP C 3 245 ? 344.643 328.239 435.664 1.00 90.13  ? 245 TRP A CD1 1 
ATOM 3217 C CD2 . TRP C 3 245 ? 345.961 326.656 436.497 1.00 90.13  ? 245 TRP A CD2 1 
ATOM 3218 N NE1 . TRP C 3 245 ? 344.853 327.314 434.677 1.00 90.13  ? 245 TRP A NE1 1 
ATOM 3219 C CE2 . TRP C 3 245 ? 345.661 326.328 435.169 1.00 90.13  ? 245 TRP A CE2 1 
ATOM 3220 C CE3 . TRP C 3 245 ? 346.779 325.802 437.228 1.00 90.13  ? 245 TRP A CE3 1 
ATOM 3221 C CZ2 . TRP C 3 245 ? 346.148 325.189 434.558 1.00 90.13  ? 245 TRP A CZ2 1 
ATOM 3222 C CZ3 . TRP C 3 245 ? 347.259 324.673 436.620 1.00 90.13  ? 245 TRP A CZ3 1 
ATOM 3223 C CH2 . TRP C 3 245 ? 346.944 324.374 435.300 1.00 90.13  ? 245 TRP A CH2 1 
ATOM 3224 N N   . VAL C 3 246 ? 344.585 331.629 439.032 1.00 83.74  ? 246 VAL A N   1 
ATOM 3225 C CA  . VAL C 3 246 ? 343.894 332.403 440.070 1.00 83.74  ? 246 VAL A CA  1 
ATOM 3226 C C   . VAL C 3 246 ? 344.856 333.309 440.837 1.00 83.74  ? 246 VAL A C   1 
ATOM 3227 O O   . VAL C 3 246 ? 345.357 332.919 441.901 1.00 83.74  ? 246 VAL A O   1 
ATOM 3228 C CB  . VAL C 3 246 ? 343.120 331.474 441.019 1.00 83.74  ? 246 VAL A CB  1 
ATOM 3229 C CG1 . VAL C 3 246 ? 342.230 332.270 441.959 1.00 83.74  ? 246 VAL A CG1 1 
ATOM 3230 C CG2 . VAL C 3 246 ? 342.286 330.507 440.229 1.00 83.74  ? 246 VAL A CG2 1 
ATOM 3231 N N   . PRO C 3 247 ? 345.229 334.462 440.287 1.00 79.71  ? 247 PRO A N   1 
ATOM 3232 C CA  . PRO C 3 247 ? 346.178 335.346 440.973 1.00 79.71  ? 247 PRO A CA  1 
ATOM 3233 C C   . PRO C 3 247 ? 345.621 335.910 442.269 1.00 79.71  ? 247 PRO A C   1 
ATOM 3234 O O   . PRO C 3 247 ? 344.411 336.001 442.464 1.00 79.71  ? 247 PRO A O   1 
ATOM 3235 C CB  . PRO C 3 247 ? 346.414 336.455 439.951 1.00 79.71  ? 247 PRO A CB  1 
ATOM 3236 C CG  . PRO C 3 247 ? 345.168 336.483 439.169 1.00 79.71  ? 247 PRO A CG  1 
ATOM 3237 C CD  . PRO C 3 247 ? 344.728 335.065 439.047 1.00 79.71  ? 247 PRO A CD  1 
ATOM 3238 N N   . ARG C 3 248 ? 346.531 336.295 443.157 1.00 83.93  ? 248 ARG A N   1 
ATOM 3239 C CA  . ARG C 3 248 ? 346.274 336.676 444.537 1.00 83.93  ? 248 ARG A CA  1 
ATOM 3240 C C   . ARG C 3 248 ? 347.029 337.958 444.851 1.00 83.93  ? 248 ARG A C   1 
ATOM 3241 O O   . ARG C 3 248 ? 348.126 338.164 444.330 1.00 83.93  ? 248 ARG A O   1 
ATOM 3242 C CB  . ARG C 3 248 ? 346.727 335.547 445.479 1.00 83.93  ? 248 ARG A CB  1 
ATOM 3243 C CG  . ARG C 3 248 ? 346.351 335.682 446.937 1.00 83.93  ? 248 ARG A CG  1 
ATOM 3244 C CD  . ARG C 3 248 ? 346.465 334.382 447.660 1.00 83.93  ? 248 ARG A CD  1 
ATOM 3245 N NE  . ARG C 3 248 ? 345.717 333.342 446.981 1.00 83.93  ? 248 ARG A NE  1 
ATOM 3246 C CZ  . ARG C 3 248 ? 344.517 332.936 447.361 1.00 83.93  ? 248 ARG A CZ  1 
ATOM 3247 N NH1 . ARG C 3 248 ? 343.937 333.487 448.413 1.00 83.93  ? 248 ARG A NH1 1 
ATOM 3248 N NH2 . ARG C 3 248 ? 343.900 331.979 446.689 1.00 83.93  ? 248 ARG A NH2 1 
ATOM 3249 N N   . PRO C 3 249 ? 346.468 338.848 445.667 1.00 78.60  ? 249 PRO A N   1 
ATOM 3250 C CA  . PRO C 3 249 ? 347.173 340.078 446.018 1.00 78.60  ? 249 PRO A CA  1 
ATOM 3251 C C   . PRO C 3 249 ? 348.347 339.789 446.934 1.00 78.60  ? 249 PRO A C   1 
ATOM 3252 O O   . PRO C 3 249 ? 348.313 338.813 447.694 1.00 78.60  ? 249 PRO A O   1 
ATOM 3253 C CB  . PRO C 3 249 ? 346.095 340.901 446.731 1.00 78.60  ? 249 PRO A CB  1 
ATOM 3254 C CG  . PRO C 3 249 ? 345.136 339.911 447.207 1.00 78.60  ? 249 PRO A CG  1 
ATOM 3255 C CD  . PRO C 3 249 ? 345.081 338.889 446.146 1.00 78.60  ? 249 PRO A CD  1 
ATOM 3256 N N   . PRO C 3 250 ? 349.397 340.613 446.893 1.00 83.68  ? 250 PRO A N   1 
ATOM 3257 C CA  . PRO C 3 250 ? 350.658 340.244 447.546 1.00 83.68  ? 250 PRO A CA  1 
ATOM 3258 C C   . PRO C 3 250 ? 350.589 340.399 449.053 1.00 83.68  ? 250 PRO A C   1 
ATOM 3259 O O   . PRO C 3 250 ? 349.984 341.336 449.571 1.00 83.68  ? 250 PRO A O   1 
ATOM 3260 C CB  . PRO C 3 250 ? 351.662 341.234 446.955 1.00 83.68  ? 250 PRO A CB  1 
ATOM 3261 C CG  . PRO C 3 250 ? 351.012 341.777 445.747 1.00 83.68  ? 250 PRO A CG  1 
ATOM 3262 C CD  . PRO C 3 250 ? 349.564 341.801 446.047 1.00 83.68  ? 250 PRO A CD  1 
ATOM 3263 N N   . ARG C 3 251 ? 351.259 339.489 449.752 1.00 89.89  ? 251 ARG A N   1 
ATOM 3264 C CA  . ARG C 3 251 ? 351.227 339.474 451.206 1.00 89.89  ? 251 ARG A CA  1 
ATOM 3265 C C   . ARG C 3 251 ? 352.006 340.647 451.778 1.00 89.89  ? 251 ARG A C   1 
ATOM 3266 O O   . ARG C 3 251 ? 353.217 340.763 451.579 1.00 89.89  ? 251 ARG A O   1 
ATOM 3267 C CB  . ARG C 3 251 ? 351.796 338.171 451.742 1.00 89.89  ? 251 ARG A CB  1 
ATOM 3268 C CG  . ARG C 3 251 ? 351.891 338.153 453.248 1.00 89.89  ? 251 ARG A CG  1 
ATOM 3269 C CD  . ARG C 3 251 ? 351.839 336.740 453.761 1.00 89.89  ? 251 ARG A CD  1 
ATOM 3270 N NE  . ARG C 3 251 ? 352.319 336.638 455.129 1.00 89.89  ? 251 ARG A NE  1 
ATOM 3271 C CZ  . ARG C 3 251 ? 351.529 336.409 456.165 1.00 89.89  ? 251 ARG A CZ  1 
ATOM 3272 N NH1 . ARG C 3 251 ? 350.229 336.260 455.978 1.00 89.89  ? 251 ARG A NH1 1 
ATOM 3273 N NH2 . ARG C 3 251 ? 352.036 336.325 457.382 1.00 89.89  ? 251 ARG A NH2 1 
ATOM 3274 N N   . LEU C 3 252 ? 351.306 341.499 452.513 1.00 90.78  ? 252 LEU A N   1 
ATOM 3275 C CA  . LEU C 3 252 ? 351.851 342.746 453.021 1.00 90.78  ? 252 LEU A CA  1 
ATOM 3276 C C   . LEU C 3 252 ? 352.555 342.567 454.358 1.00 90.78  ? 252 LEU A C   1 
ATOM 3277 O O   . LEU C 3 252 ? 353.660 343.078 454.549 1.00 90.78  ? 252 LEU A O   1 
ATOM 3278 C CB  . LEU C 3 252 ? 350.723 343.767 453.142 1.00 90.78  ? 252 LEU A CB  1 
ATOM 3279 C CG  . LEU C 3 252 ? 350.904 344.944 454.081 1.00 90.78  ? 252 LEU A CG  1 
ATOM 3280 C CD1 . LEU C 3 252 ? 351.886 345.919 453.497 1.00 90.78  ? 252 LEU A CD1 1 
ATOM 3281 C CD2 . LEU C 3 252 ? 349.567 345.605 454.299 1.00 90.78  ? 252 LEU A CD2 1 
ATOM 3282 N N   . CYS C 3 253 ? 351.934 341.847 455.288 1.00 98.26  ? 253 CYS A N   1 
ATOM 3283 C CA  . CYS C 3 253 ? 352.517 341.641 456.603 1.00 98.26  ? 253 CYS A CA  1 
ATOM 3284 C C   . CYS C 3 253 ? 353.676 340.652 456.527 1.00 98.26  ? 253 CYS A C   1 
ATOM 3285 O O   . CYS C 3 253 ? 353.962 340.062 455.484 1.00 98.26  ? 253 CYS A O   1 
ATOM 3286 C CB  . CYS C 3 253 ? 351.464 341.131 457.579 1.00 98.26  ? 253 CYS A CB  1 
ATOM 3287 S SG  . CYS C 3 253 ? 349.843 341.873 457.353 1.00 98.26  ? 253 CYS A SG  1 
ATOM 3288 N N   . GLN C 3 254 ? 354.336 340.455 457.661 1.00 99.36  ? 254 GLN A N   1 
ATOM 3289 C CA  . GLN C 3 254 ? 355.505 339.594 457.698 1.00 99.36  ? 254 GLN A CA  1 
ATOM 3290 C C   . GLN C 3 254 ? 355.106 338.121 457.742 1.00 99.36  ? 254 GLN A C   1 
ATOM 3291 O O   . GLN C 3 254 ? 353.930 337.760 457.687 1.00 99.36  ? 254 GLN A O   1 
ATOM 3292 C CB  . GLN C 3 254 ? 356.374 339.942 458.896 1.00 99.36  ? 254 GLN A CB  1 
ATOM 3293 C CG  . GLN C 3 254 ? 357.086 341.245 458.719 1.00 99.36  ? 254 GLN A CG  1 
ATOM 3294 C CD  . GLN C 3 254 ? 357.964 341.232 457.497 1.00 99.36  ? 254 GLN A CD  1 
ATOM 3295 O OE1 . GLN C 3 254 ? 358.757 340.313 457.302 1.00 99.36  ? 254 GLN A OE1 1 
ATOM 3296 N NE2 . GLN C 3 254 ? 357.817 342.242 456.653 1.00 99.36  ? 254 GLN A NE2 1 
ATOM 3297 N N   . TYR C 3 255 ? 356.116 337.263 457.830 1.00 96.54  ? 255 TYR A N   1 
ATOM 3298 C CA  . TYR C 3 255 ? 355.923 335.824 457.953 1.00 96.54  ? 255 TYR A CA  1 
ATOM 3299 C C   . TYR C 3 255 ? 356.423 335.392 459.320 1.00 96.54  ? 255 TYR A C   1 
ATOM 3300 O O   . TYR C 3 255 ? 357.477 335.851 459.767 1.00 96.54  ? 255 TYR A O   1 
ATOM 3301 C CB  . TYR C 3 255 ? 356.675 335.074 456.858 1.00 96.54  ? 255 TYR A CB  1 
ATOM 3302 C CG  . TYR C 3 255 ? 356.128 335.294 455.478 1.00 96.54  ? 255 TYR A CG  1 
ATOM 3303 C CD1 . TYR C 3 255 ? 356.545 336.369 454.711 1.00 96.54  ? 255 TYR A CD1 1 
ATOM 3304 C CD2 . TYR C 3 255 ? 355.201 334.424 454.937 1.00 96.54  ? 255 TYR A CD2 1 
ATOM 3305 C CE1 . TYR C 3 255 ? 356.048 336.571 453.446 1.00 96.54  ? 255 TYR A CE1 1 
ATOM 3306 C CE2 . TYR C 3 255 ? 354.703 334.616 453.674 1.00 96.54  ? 255 TYR A CE2 1 
ATOM 3307 C CZ  . TYR C 3 255 ? 355.128 335.692 452.934 1.00 96.54  ? 255 TYR A CZ  1 
ATOM 3308 O OH  . TYR C 3 255 ? 354.631 335.891 451.672 1.00 96.54  ? 255 TYR A OH  1 
ATOM 3309 N N   . GLU C 3 256 ? 355.665 334.532 459.994 1.00 103.77 ? 256 GLU A N   1 
ATOM 3310 C CA  . GLU C 3 256 ? 356.076 334.072 461.312 1.00 103.77 ? 256 GLU A CA  1 
ATOM 3311 C C   . GLU C 3 256 ? 356.226 332.560 461.405 1.00 103.77 ? 256 GLU A C   1 
ATOM 3312 O O   . GLU C 3 256 ? 357.220 332.073 461.946 1.00 103.77 ? 256 GLU A O   1 
ATOM 3313 C CB  . GLU C 3 256 ? 355.091 334.570 462.374 1.00 103.77 ? 256 GLU A CB  1 
ATOM 3314 C CG  . GLU C 3 256 ? 354.892 336.078 462.356 1.00 103.77 ? 256 GLU A CG  1 
ATOM 3315 C CD  . GLU C 3 256 ? 356.117 336.850 462.819 1.00 103.77 ? 256 GLU A CD  1 
ATOM 3316 O OE1 . GLU C 3 256 ? 356.967 336.277 463.534 1.00 103.77 ? 256 GLU A OE1 1 
ATOM 3317 O OE2 . GLU C 3 256 ? 356.238 338.040 462.462 1.00 103.77 ? 256 GLU A OE2 1 
ATOM 3318 N N   . LYS C 3 257 ? 355.264 331.806 460.896 1.00 103.69 ? 257 LYS A N   1 
ATOM 3319 C CA  . LYS C 3 257 ? 355.310 330.356 460.953 1.00 103.69 ? 257 LYS A CA  1 
ATOM 3320 C C   . LYS C 3 257 ? 355.512 329.797 459.555 1.00 103.69 ? 257 LYS A C   1 
ATOM 3321 O O   . LYS C 3 257 ? 355.210 330.443 458.551 1.00 103.69 ? 257 LYS A O   1 
ATOM 3322 C CB  . LYS C 3 257 ? 354.032 329.785 461.573 1.00 103.69 ? 257 LYS A CB  1 
ATOM 3323 C CG  . LYS C 3 257 ? 354.019 329.814 463.081 1.00 103.69 ? 257 LYS A CG  1 
ATOM 3324 C CD  . LYS C 3 257 ? 354.981 328.792 463.638 1.00 103.69 ? 257 LYS A CD  1 
ATOM 3325 C CE  . LYS C 3 257 ? 354.965 328.795 465.153 1.00 103.69 ? 257 LYS A CE  1 
ATOM 3326 N NZ  . LYS C 3 257 ? 355.880 327.762 465.718 1.00 103.69 ? 257 LYS A NZ  1 
ATOM 3327 N N   . GLN C 3 258 ? 356.024 328.573 459.496 1.00 98.47  ? 258 GLN A N   1 
ATOM 3328 C CA  . GLN C 3 258 ? 356.236 327.936 458.207 1.00 98.47  ? 258 GLN A CA  1 
ATOM 3329 C C   . GLN C 3 258 ? 354.973 327.280 457.674 1.00 98.47  ? 258 GLN A C   1 
ATOM 3330 O O   . GLN C 3 258 ? 354.592 327.510 456.522 1.00 98.47  ? 258 GLN A O   1 
ATOM 3331 C CB  . GLN C 3 258 ? 357.350 326.893 458.307 1.00 98.47  ? 258 GLN A CB  1 
ATOM 3332 C CG  . GLN C 3 258 ? 357.421 325.972 457.101 1.00 98.47  ? 258 GLN A CG  1 
ATOM 3333 C CD  . GLN C 3 258 ? 358.728 325.224 457.001 1.00 98.47  ? 258 GLN A CD  1 
ATOM 3334 O OE1 . GLN C 3 258 ? 358.874 324.320 456.180 1.00 98.47  ? 258 GLN A OE1 1 
ATOM 3335 N NE2 . GLN C 3 258 ? 359.691 325.598 457.834 1.00 98.47  ? 258 GLN A NE2 1 
ATOM 3336 N N   . LYS C 3 259 ? 354.307 326.481 458.500 1.00 98.76  ? 259 LYS A N   1 
ATOM 3337 C CA  . LYS C 3 259 ? 353.231 325.633 458.008 1.00 98.76  ? 259 LYS A CA  1 
ATOM 3338 C C   . LYS C 3 259 ? 351.952 326.418 457.747 1.00 98.76  ? 259 LYS A C   1 
ATOM 3339 O O   . LYS C 3 259 ? 351.121 325.995 456.939 1.00 98.76  ? 259 LYS A O   1 
ATOM 3340 C CB  . LYS C 3 259 ? 352.966 324.513 459.007 1.00 98.76  ? 259 LYS A CB  1 
ATOM 3341 C CG  . LYS C 3 259 ? 354.171 323.638 459.271 1.00 98.76  ? 259 LYS A CG  1 
ATOM 3342 C CD  . LYS C 3 259 ? 353.826 322.529 460.241 1.00 98.76  ? 259 LYS A CD  1 
ATOM 3343 C CE  . LYS C 3 259 ? 353.502 323.097 461.611 1.00 98.76  ? 259 LYS A CE  1 
ATOM 3344 N NZ  . LYS C 3 259 ? 354.676 323.765 462.229 1.00 98.76  ? 259 LYS A NZ  1 
ATOM 3345 N N   . ASN C 3 260 ? 351.768 327.548 458.416 1.00 95.90  ? 260 ASN A N   1 
ATOM 3346 C CA  . ASN C 3 260 ? 350.510 328.273 458.340 1.00 95.90  ? 260 ASN A CA  1 
ATOM 3347 C C   . ASN C 3 260 ? 350.754 329.731 457.957 1.00 95.90  ? 260 ASN A C   1 
ATOM 3348 O O   . ASN C 3 260 ? 351.860 330.126 457.587 1.00 95.90  ? 260 ASN A O   1 
ATOM 3349 C CB  . ASN C 3 260 ? 349.751 328.149 459.658 1.00 95.90  ? 260 ASN A CB  1 
ATOM 3350 C CG  . ASN C 3 260 ? 350.561 328.622 460.829 1.00 95.90  ? 260 ASN A CG  1 
ATOM 3351 O OD1 . ASN C 3 260 ? 350.563 329.804 461.154 1.00 95.90  ? 260 ASN A OD1 1 
ATOM 3352 N ND2 . ASN C 3 260 ? 351.262 327.701 461.474 1.00 95.90  ? 260 ASN A ND2 1 
ATOM 3353 N N   . VAL C 3 261 ? 349.696 330.531 458.061 1.00 88.27  ? 261 VAL A N   1 
ATOM 3354 C CA  . VAL C 3 261 ? 349.619 331.830 457.405 1.00 88.27  ? 261 VAL A CA  1 
ATOM 3355 C C   . VAL C 3 261 ? 349.417 332.926 458.451 1.00 88.27  ? 261 VAL A C   1 
ATOM 3356 O O   . VAL C 3 261 ? 349.081 334.071 458.123 1.00 88.27  ? 261 VAL A O   1 
ATOM 3357 C CB  . VAL C 3 261 ? 348.501 331.783 456.337 1.00 88.27  ? 261 VAL A CB  1 
ATOM 3358 C CG1 . VAL C 3 261 ? 347.109 331.819 456.964 1.00 88.27  ? 261 VAL A CG1 1 
ATOM 3359 C CG2 . VAL C 3 261 ? 348.690 332.827 455.225 1.00 88.27  ? 261 VAL A CG2 1 
ATOM 3360 N N   . ASN C 3 262 ? 349.681 332.593 459.714 1.00 94.11  ? 262 ASN A N   1 
ATOM 3361 C CA  . ASN C 3 262 ? 349.465 333.515 460.823 1.00 94.11  ? 262 ASN A CA  1 
ATOM 3362 C C   . ASN C 3 262 ? 350.372 334.734 460.724 1.00 94.11  ? 262 ASN A C   1 
ATOM 3363 O O   . ASN C 3 262 ? 351.436 334.695 460.103 1.00 94.11  ? 262 ASN A O   1 
ATOM 3364 C CB  . ASN C 3 262 ? 349.714 332.813 462.151 1.00 94.11  ? 262 ASN A CB  1 
ATOM 3365 C CG  . ASN C 3 262 ? 348.521 332.030 462.620 1.00 94.11  ? 262 ASN A CG  1 
ATOM 3366 O OD1 . ASN C 3 262 ? 347.386 332.487 462.515 1.00 94.11  ? 262 ASN A OD1 1 
ATOM 3367 N ND2 . ASN C 3 262 ? 348.767 330.838 463.142 1.00 94.11  ? 262 ASN A ND2 1 
ATOM 3368 N N   . PHE C 3 263 ? 349.932 335.830 461.333 1.00 91.41  ? 263 PHE A N   1 
ATOM 3369 C CA  . PHE C 3 263 ? 350.622 337.102 461.182 1.00 91.41  ? 263 PHE A CA  1 
ATOM 3370 C C   . PHE C 3 263 ? 350.270 338.010 462.347 1.00 91.41  ? 263 PHE A C   1 
ATOM 3371 O O   . PHE C 3 263 ? 349.397 337.707 463.161 1.00 91.41  ? 263 PHE A O   1 
ATOM 3372 C CB  . PHE C 3 263 ? 350.268 337.780 459.855 1.00 91.41  ? 263 PHE A CB  1 
ATOM 3373 C CG  . PHE C 3 263 ? 348.801 338.060 459.676 1.00 91.41  ? 263 PHE A CG  1 
ATOM 3374 C CD1 . PHE C 3 263 ? 347.959 337.099 459.155 1.00 91.41  ? 263 PHE A CD1 1 
ATOM 3375 C CD2 . PHE C 3 263 ? 348.273 339.299 459.986 1.00 91.41  ? 263 PHE A CD2 1 
ATOM 3376 C CE1 . PHE C 3 263 ? 346.623 337.358 458.983 1.00 91.41  ? 263 PHE A CE1 1 
ATOM 3377 C CE2 . PHE C 3 263 ? 346.936 339.558 459.815 1.00 91.41  ? 263 PHE A CE2 1 
ATOM 3378 C CZ  . PHE C 3 263 ? 346.113 338.588 459.310 1.00 91.41  ? 263 PHE A CZ  1 
ATOM 3379 N N   . SER C 3 264 ? 350.960 339.142 462.399 1.00 90.17  ? 264 SER A N   1 
ATOM 3380 C CA  . SER C 3 264 ? 350.625 340.248 463.266 1.00 90.17  ? 264 SER A CA  1 
ATOM 3381 C C   . SER C 3 264 ? 350.121 341.408 462.420 1.00 90.17  ? 264 SER A C   1 
ATOM 3382 O O   . SER C 3 264 ? 350.647 341.634 461.327 1.00 90.17  ? 264 SER A O   1 
ATOM 3383 C CB  . SER C 3 264 ? 351.840 340.697 464.081 1.00 90.17  ? 264 SER A CB  1 
ATOM 3384 O OG  . SER C 3 264 ? 351.634 341.986 464.624 1.00 90.17  ? 264 SER A OG  1 
ATOM 3385 N N   . PRO C 3 265 ? 349.103 342.137 462.873 1.00 88.13  ? 265 PRO A N   1 
ATOM 3386 C CA  . PRO C 3 265 ? 348.552 343.216 462.049 1.00 88.13  ? 265 PRO A CA  1 
ATOM 3387 C C   . PRO C 3 265 ? 349.515 344.379 461.963 1.00 88.13  ? 265 PRO A C   1 
ATOM 3388 O O   . PRO C 3 265 ? 350.265 344.656 462.899 1.00 88.13  ? 265 PRO A O   1 
ATOM 3389 C CB  . PRO C 3 265 ? 347.271 343.614 462.787 1.00 88.13  ? 265 PRO A CB  1 
ATOM 3390 C CG  . PRO C 3 265 ? 347.032 342.537 463.776 1.00 88.13  ? 265 PRO A CG  1 
ATOM 3391 C CD  . PRO C 3 265 ? 348.361 341.990 464.129 1.00 88.13  ? 265 PRO A CD  1 
ATOM 3392 N N   . ILE C 3 266 ? 349.503 345.054 460.819 1.00 87.94  ? 266 ILE A N   1 
ATOM 3393 C CA  . ILE C 3 266 ? 350.439 346.134 460.560 1.00 87.94  ? 266 ILE A CA  1 
ATOM 3394 C C   . ILE C 3 266 ? 349.718 347.168 459.708 1.00 87.94  ? 266 ILE A C   1 
ATOM 3395 O O   . ILE C 3 266 ? 348.678 346.891 459.107 1.00 87.94  ? 266 ILE A O   1 
ATOM 3396 C CB  . ILE C 3 266 ? 351.720 345.604 459.875 1.00 87.94  ? 266 ILE A CB  1 
ATOM 3397 C CG1 . ILE C 3 266 ? 352.912 346.531 460.104 1.00 87.94  ? 266 ILE A CG1 1 
ATOM 3398 C CG2 . ILE C 3 266 ? 351.501 345.416 458.394 1.00 87.94  ? 266 ILE A CG2 1 
ATOM 3399 C CD1 . ILE C 3 266 ? 354.236 345.900 459.755 1.00 87.94  ? 266 ILE A CD1 1 
ATOM 3400 N N   . GLY C 3 267 ? 350.256 348.384 459.697 1.00 93.90  ? 267 GLY A N   1 
ATOM 3401 C CA  . GLY C 3 267 ? 349.667 349.445 458.914 1.00 93.90  ? 267 GLY A CA  1 
ATOM 3402 C C   . GLY C 3 267 ? 349.787 349.201 457.425 1.00 93.90  ? 267 GLY A C   1 
ATOM 3403 O O   . GLY C 3 267 ? 350.527 348.337 456.958 1.00 93.90  ? 267 GLY A O   1 
ATOM 3404 N N   . VAL C 3 268 ? 349.033 349.991 456.665 1.00 97.25  ? 268 VAL A N   1 
ATOM 3405 C CA  . VAL C 3 268 ? 348.916 349.747 455.234 1.00 97.25  ? 268 VAL A CA  1 
ATOM 3406 C C   . VAL C 3 268 ? 350.148 350.251 454.499 1.00 97.25  ? 268 VAL A C   1 
ATOM 3407 O O   . VAL C 3 268 ? 350.755 349.527 453.705 1.00 97.25  ? 268 VAL A O   1 
ATOM 3408 C CB  . VAL C 3 268 ? 347.634 350.393 454.691 1.00 97.25  ? 268 VAL A CB  1 
ATOM 3409 C CG1 . VAL C 3 268 ? 347.557 350.201 453.206 1.00 97.25  ? 268 VAL A CG1 1 
ATOM 3410 C CG2 . VAL C 3 268 ? 346.429 349.790 455.361 1.00 97.25  ? 268 VAL A CG2 1 
ATOM 3411 N N   . THR C 3 269 ? 350.542 351.492 454.756 1.00 108.79 ? 269 THR A N   1 
ATOM 3412 C CA  . THR C 3 269 ? 351.593 352.134 453.985 1.00 108.79 ? 269 THR A CA  1 
ATOM 3413 C C   . THR C 3 269 ? 352.410 353.019 454.913 1.00 108.79 ? 269 THR A C   1 
ATOM 3414 O O   . THR C 3 269 ? 351.870 353.648 455.824 1.00 108.79 ? 269 THR A O   1 
ATOM 3415 C CB  . THR C 3 269 ? 350.971 352.921 452.816 1.00 108.79 ? 269 THR A CB  1 
ATOM 3416 O OG1 . THR C 3 269 ? 350.454 351.995 451.858 1.00 108.79 ? 269 THR A OG1 1 
ATOM 3417 C CG2 . THR C 3 269 ? 351.972 353.827 452.109 1.00 108.79 ? 269 THR A CG2 1 
ATOM 3418 N N   . THR C 3 270 ? 353.731 352.997 454.713 1.00 112.88 ? 270 THR A N   1 
ATOM 3419 C CA  . THR C 3 270 ? 354.637 353.933 455.363 1.00 112.88 ? 270 THR A CA  1 
ATOM 3420 C C   . THR C 3 270 ? 354.192 355.369 455.116 1.00 112.88 ? 270 THR A C   1 
ATOM 3421 O O   . THR C 3 270 ? 354.138 355.843 453.980 1.00 112.88 ? 270 THR A O   1 
ATOM 3422 C CB  . THR C 3 270 ? 356.057 353.750 454.838 1.00 112.88 ? 270 THR A CB  1 
ATOM 3423 O OG1 . THR C 3 270 ? 356.200 354.462 453.603 1.00 112.88 ? 270 THR A OG1 1 
ATOM 3424 C CG2 . THR C 3 270 ? 356.345 352.280 454.593 1.00 112.88 ? 270 THR A CG2 1 
ATOM 3425 N N   . SER C 3 271 ? 353.865 356.055 456.199 1.00 105.67 ? 271 SER A N   1 
ATOM 3426 C CA  . SER C 3 271 ? 353.090 357.280 456.129 1.00 105.67 ? 271 SER A CA  1 
ATOM 3427 C C   . SER C 3 271 ? 353.950 358.486 455.796 1.00 105.67 ? 271 SER A C   1 
ATOM 3428 O O   . SER C 3 271 ? 355.154 358.525 456.054 1.00 105.67 ? 271 SER A O   1 
ATOM 3429 C CB  . SER C 3 271 ? 352.355 357.531 457.439 1.00 105.67 ? 271 SER A CB  1 
ATOM 3430 O OG  . SER C 3 271 ? 351.719 358.794 457.405 1.00 105.67 ? 271 SER A OG  1 
ATOM 3431 N N   . ARG C 3 272 ? 353.293 359.484 455.219 1.00 99.06  ? 272 ARG A N   1 
ATOM 3432 C CA  . ARG C 3 272 ? 353.860 360.797 454.988 1.00 99.06  ? 272 ARG A CA  1 
ATOM 3433 C C   . ARG C 3 272 ? 353.232 361.757 455.981 1.00 99.06  ? 272 ARG A C   1 
ATOM 3434 O O   . ARG C 3 272 ? 352.257 361.431 456.660 1.00 99.06  ? 272 ARG A O   1 
ATOM 3435 C CB  . ARG C 3 272 ? 353.611 361.269 453.557 1.00 99.06  ? 272 ARG A CB  1 
ATOM 3436 C CG  . ARG C 3 272 ? 352.151 361.280 453.185 1.00 99.06  ? 272 ARG A CG  1 
ATOM 3437 C CD  . ARG C 3 272 ? 351.963 361.754 451.770 1.00 99.06  ? 272 ARG A CD  1 
ATOM 3438 N NE  . ARG C 3 272 ? 350.557 361.938 451.456 1.00 99.06  ? 272 ARG A NE  1 
ATOM 3439 C CZ  . ARG C 3 272 ? 350.115 362.770 450.527 1.00 99.06  ? 272 ARG A CZ  1 
ATOM 3440 N NH1 . ARG C 3 272 ? 350.974 363.493 449.830 1.00 99.06  ? 272 ARG A NH1 1 
ATOM 3441 N NH2 . ARG C 3 272 ? 348.819 362.884 450.297 1.00 99.06  ? 272 ARG A NH2 1 
ATOM 3442 N N   . THR C 3 273 ? 353.792 362.957 456.056 1.00 105.44 ? 273 THR A N   1 
ATOM 3443 C CA  . THR C 3 273 ? 353.430 363.844 457.149 1.00 105.44 ? 273 THR A CA  1 
ATOM 3444 C C   . THR C 3 273 ? 352.100 364.550 456.929 1.00 105.44 ? 273 THR A C   1 
ATOM 3445 O O   . THR C 3 273 ? 351.472 364.970 457.904 1.00 105.44 ? 273 THR A O   1 
ATOM 3446 C CB  . THR C 3 273 ? 354.542 364.865 457.381 1.00 105.44 ? 273 THR A CB  1 
ATOM 3447 O OG1 . THR C 3 273 ? 354.201 365.693 458.497 1.00 105.44 ? 273 THR A OG1 1 
ATOM 3448 C CG2 . THR C 3 273 ? 354.762 365.722 456.153 1.00 105.44 ? 273 THR A CG2 1 
ATOM 3449 N N   . ASP C 3 274 ? 351.639 364.680 455.689 1.00 107.23 ? 274 ASP A N   1 
ATOM 3450 C CA  . ASP C 3 274 ? 350.443 365.465 455.429 1.00 107.23 ? 274 ASP A CA  1 
ATOM 3451 C C   . ASP C 3 274 ? 349.747 364.956 454.178 1.00 107.23 ? 274 ASP A C   1 
ATOM 3452 O O   . ASP C 3 274 ? 350.284 364.146 453.418 1.00 107.23 ? 274 ASP A O   1 
ATOM 3453 C CB  . ASP C 3 274 ? 350.777 366.950 455.289 1.00 107.23 ? 274 ASP A CB  1 
ATOM 3454 C CG  . ASP C 3 274 ? 350.702 367.679 456.599 1.00 107.23 ? 274 ASP A CG  1 
ATOM 3455 O OD1 . ASP C 3 274 ? 349.733 367.445 457.348 1.00 107.23 ? 274 ASP A OD1 1 
ATOM 3456 O OD2 . ASP C 3 274 ? 351.614 368.477 456.887 1.00 107.23 ? 274 ASP A OD2 1 
ATOM 3457 N N   . ILE C 3 275 ? 348.535 365.458 453.969 1.00 103.26 ? 275 ILE A N   1 
ATOM 3458 C CA  . ILE C 3 275 ? 347.769 365.105 452.789 1.00 103.26 ? 275 ILE A CA  1 
ATOM 3459 C C   . ILE C 3 275 ? 348.178 365.950 451.585 1.00 103.26 ? 275 ILE A C   1 
ATOM 3460 O O   . ILE C 3 275 ? 348.227 365.442 450.462 1.00 103.26 ? 275 ILE A O   1 
ATOM 3461 C CB  . ILE C 3 275 ? 346.267 365.226 453.113 1.00 103.26 ? 275 ILE A CB  1 
ATOM 3462 C CG1 . ILE C 3 275 ? 345.390 364.976 451.890 1.00 103.26 ? 275 ILE A CG1 1 
ATOM 3463 C CG2 . ILE C 3 275 ? 345.947 366.558 453.760 1.00 103.26 ? 275 ILE A CG2 1 
ATOM 3464 C CD1 . ILE C 3 275 ? 343.937 364.843 452.222 1.00 103.26 ? 275 ILE A CD1 1 
ATOM 3465 N N   . ILE C 3 276 ? 348.551 367.206 451.797 1.00 100.45 ? 276 ILE A N   1 
ATOM 3466 C CA  . ILE C 3 276 ? 348.900 368.086 450.696 1.00 100.45 ? 276 ILE A CA  1 
ATOM 3467 C C   . ILE C 3 276 ? 350.405 368.154 450.507 1.00 100.45 ? 276 ILE A C   1 
ATOM 3468 O O   . ILE C 3 276 ? 350.893 368.851 449.620 1.00 100.45 ? 276 ILE A O   1 
ATOM 3469 C CB  . ILE C 3 276 ? 348.333 369.471 450.923 1.00 100.45 ? 276 ILE A CB  1 
ATOM 3470 C CG1 . ILE C 3 276 ? 349.093 370.158 452.053 1.00 100.45 ? 276 ILE A CG1 1 
ATOM 3471 C CG2 . ILE C 3 276 ? 346.874 369.370 451.289 1.00 100.45 ? 276 ILE A CG2 1 
ATOM 3472 C CD1 . ILE C 3 276 ? 348.583 371.538 452.381 1.00 100.45 ? 276 ILE A CD1 1 
ATOM 3473 N N   . ARG D 4 14  ? 313.888 341.174 434.595 1.00 110.50 ? 14  ARG B N   1 
ATOM 3474 C CA  . ARG D 4 14  ? 313.000 341.416 435.722 1.00 110.50 ? 14  ARG B CA  1 
ATOM 3475 C C   . ARG D 4 14  ? 312.126 340.212 436.035 1.00 110.50 ? 14  ARG B C   1 
ATOM 3476 O O   . ARG D 4 14  ? 311.665 339.520 435.126 1.00 110.50 ? 14  ARG B O   1 
ATOM 3477 C CB  . ARG D 4 14  ? 312.112 342.624 435.454 1.00 110.50 ? 14  ARG B CB  1 
ATOM 3478 C CG  . ARG D 4 14  ? 312.853 343.854 434.991 1.00 110.50 ? 14  ARG B CG  1 
ATOM 3479 C CD  . ARG D 4 14  ? 311.883 344.999 434.789 1.00 110.50 ? 14  ARG B CD  1 
ATOM 3480 N NE  . ARG D 4 14  ? 310.823 344.967 435.789 1.00 110.50 ? 14  ARG B NE  1 
ATOM 3481 C CZ  . ARG D 4 14  ? 310.879 345.603 436.950 1.00 110.50 ? 14  ARG B CZ  1 
ATOM 3482 N NH1 . ARG D 4 14  ? 311.941 346.330 437.255 1.00 110.50 ? 14  ARG B NH1 1 
ATOM 3483 N NH2 . ARG D 4 14  ? 309.870 345.516 437.802 1.00 110.50 ? 14  ARG B NH2 1 
ATOM 3484 N N   . SER D 4 15  ? 311.888 340.011 437.335 1.00 112.05 ? 15  SER B N   1 
ATOM 3485 C CA  . SER D 4 15  ? 311.073 338.927 437.896 1.00 112.05 ? 15  SER B CA  1 
ATOM 3486 C C   . SER D 4 15  ? 311.562 337.558 437.427 1.00 112.05 ? 15  SER B C   1 
ATOM 3487 O O   . SER D 4 15  ? 310.855 336.808 436.756 1.00 112.05 ? 15  SER B O   1 
ATOM 3488 C CB  . SER D 4 15  ? 309.583 339.111 437.584 1.00 112.05 ? 15  SER B CB  1 
ATOM 3489 O OG  . SER D 4 15  ? 309.318 339.058 436.194 1.00 112.05 ? 15  SER B OG  1 
ATOM 3490 N N   . ILE D 4 16  ? 312.792 337.254 437.784 1.00 108.47 ? 16  ILE B N   1 
ATOM 3491 C CA  . ILE D 4 16  ? 313.351 335.943 437.494 1.00 108.47 ? 16  ILE B CA  1 
ATOM 3492 C C   . ILE D 4 16  ? 312.725 334.907 438.417 1.00 108.47 ? 16  ILE B C   1 
ATOM 3493 O O   . ILE D 4 16  ? 312.587 335.109 439.628 1.00 108.47 ? 16  ILE B O   1 
ATOM 3494 C CB  . ILE D 4 16  ? 314.890 335.978 437.596 1.00 108.47 ? 16  ILE B CB  1 
ATOM 3495 C CG1 . ILE D 4 16  ? 315.487 334.607 437.276 1.00 108.47 ? 16  ILE B CG1 1 
ATOM 3496 C CG2 . ILE D 4 16  ? 315.367 336.545 438.926 1.00 108.47 ? 16  ILE B CG2 1 
ATOM 3497 C CD1 . ILE D 4 16  ? 315.269 334.164 435.849 1.00 108.47 ? 16  ILE B CD1 1 
ATOM 3498 N N   . THR D 4 17  ? 312.284 333.801 437.829 1.00 109.84 ? 17  THR B N   1 
ATOM 3499 C CA  . THR D 4 17  ? 311.677 332.717 438.581 1.00 109.84 ? 17  THR B CA  1 
ATOM 3500 C C   . THR D 4 17  ? 312.497 331.450 438.406 1.00 109.84 ? 17  THR B C   1 
ATOM 3501 O O   . THR D 4 17  ? 313.064 331.199 437.339 1.00 109.84 ? 17  THR B O   1 
ATOM 3502 C CB  . THR D 4 17  ? 310.228 332.472 438.154 1.00 109.84 ? 17  THR B CB  1 
ATOM 3503 O OG1 . THR D 4 17  ? 309.751 331.264 438.760 1.00 109.84 ? 17  THR B OG1 1 
ATOM 3504 C CG2 . THR D 4 17  ? 310.108 332.382 436.638 1.00 109.84 ? 17  THR B CG2 1 
ATOM 3505 N N   . LEU D 4 18  ? 312.559 330.659 439.472 1.00 106.03 ? 18  LEU B N   1 
ATOM 3506 C CA  . LEU D 4 18  ? 313.393 329.464 439.496 1.00 106.03 ? 18  LEU B CA  1 
ATOM 3507 C C   . LEU D 4 18  ? 312.928 328.583 440.640 1.00 106.03 ? 18  LEU B C   1 
ATOM 3508 O O   . LEU D 4 18  ? 312.840 329.048 441.779 1.00 106.03 ? 18  LEU B O   1 
ATOM 3509 C CB  . LEU D 4 18  ? 314.866 329.829 439.664 1.00 106.03 ? 18  LEU B CB  1 
ATOM 3510 C CG  . LEU D 4 18  ? 315.799 328.694 440.067 1.00 106.03 ? 18  LEU B CG  1 
ATOM 3511 C CD1 . LEU D 4 18  ? 316.035 327.780 438.886 1.00 106.03 ? 18  LEU B CD1 1 
ATOM 3512 C CD2 . LEU D 4 18  ? 317.110 329.228 440.597 1.00 106.03 ? 18  LEU B CD2 1 
ATOM 3513 N N   . GLY D 4 19  ? 312.644 327.321 440.343 1.00 109.47 ? 19  GLY B N   1 
ATOM 3514 C CA  . GLY D 4 19  ? 312.158 326.410 441.357 1.00 109.47 ? 19  GLY B CA  1 
ATOM 3515 C C   . GLY D 4 19  ? 310.760 326.767 441.805 1.00 109.47 ? 19  GLY B C   1 
ATOM 3516 O O   . GLY D 4 19  ? 309.796 326.592 441.057 1.00 109.47 ? 19  GLY B O   1 
ATOM 3517 N N   . ASN D 4 20  ? 310.634 327.276 443.026 1.00 108.43 ? 20  ASN B N   1 
ATOM 3518 C CA  . ASN D 4 20  ? 309.351 327.746 443.523 1.00 108.43 ? 20  ASN B CA  1 
ATOM 3519 C C   . ASN D 4 20  ? 309.508 329.062 444.268 1.00 108.43 ? 20  ASN B C   1 
ATOM 3520 O O   . ASN D 4 20  ? 308.584 329.509 444.948 1.00 108.43 ? 20  ASN B O   1 
ATOM 3521 C CB  . ASN D 4 20  ? 308.695 326.697 444.415 1.00 108.43 ? 20  ASN B CB  1 
ATOM 3522 C CG  . ASN D 4 20  ? 309.554 326.324 445.598 1.00 108.43 ? 20  ASN B CG  1 
ATOM 3523 O OD1 . ASN D 4 20  ? 310.573 325.655 445.450 1.00 108.43 ? 20  ASN B OD1 1 
ATOM 3524 N ND2 . ASN D 4 20  ? 309.141 326.747 446.785 1.00 108.43 ? 20  ASN B ND2 1 
ATOM 3525 N N   . SER D 4 21  ? 310.669 329.697 444.146 1.00 108.31 ? 21  SER B N   1 
ATOM 3526 C CA  . SER D 4 21  ? 310.926 330.977 444.783 1.00 108.31 ? 21  SER B CA  1 
ATOM 3527 C C   . SER D 4 21  ? 311.327 331.983 443.717 1.00 108.31 ? 21  SER B C   1 
ATOM 3528 O O   . SER D 4 21  ? 312.085 331.665 442.800 1.00 108.31 ? 21  SER B O   1 
ATOM 3529 C CB  . SER D 4 21  ? 312.019 330.865 445.842 1.00 108.31 ? 21  SER B CB  1 
ATOM 3530 O OG  . SER D 4 21  ? 311.926 331.917 446.784 1.00 108.31 ? 21  SER B OG  1 
ATOM 3531 N N   . THR D 4 22  ? 310.821 333.207 443.851 1.00 108.81 ? 22  THR B N   1 
ATOM 3532 C CA  . THR D 4 22  ? 310.908 334.192 442.781 1.00 108.81 ? 22  THR B CA  1 
ATOM 3533 C C   . THR D 4 22  ? 311.265 335.550 443.362 1.00 108.81 ? 22  THR B C   1 
ATOM 3534 O O   . THR D 4 22  ? 310.611 336.012 444.299 1.00 108.81 ? 22  THR B O   1 
ATOM 3535 C CB  . THR D 4 22  ? 309.579 334.272 442.023 1.00 108.81 ? 22  THR B CB  1 
ATOM 3536 O OG1 . THR D 4 22  ? 309.346 333.037 441.341 1.00 108.81 ? 22  THR B OG1 1 
ATOM 3537 C CG2 . THR D 4 22  ? 309.588 335.397 441.016 1.00 108.81 ? 22  THR B CG2 1 
ATOM 3538 N N   . ILE D 4 23  ? 312.301 336.181 442.814 1.00 107.58 ? 23  ILE B N   1 
ATOM 3539 C CA  . ILE D 4 23  ? 312.690 337.528 443.199 1.00 107.58 ? 23  ILE B CA  1 
ATOM 3540 C C   . ILE D 4 23  ? 312.797 338.387 441.944 1.00 107.58 ? 23  ILE B C   1 
ATOM 3541 O O   . ILE D 4 23  ? 312.644 337.908 440.822 1.00 107.58 ? 23  ILE B O   1 
ATOM 3542 C CB  . ILE D 4 23  ? 314.001 337.547 443.991 1.00 107.58 ? 23  ILE B CB  1 
ATOM 3543 C CG1 . ILE D 4 23  ? 315.038 336.677 443.295 1.00 107.58 ? 23  ILE B CG1 1 
ATOM 3544 C CG2 . ILE D 4 23  ? 313.760 337.058 445.402 1.00 107.58 ? 23  ILE B CG2 1 
ATOM 3545 C CD1 . ILE D 4 23  ? 316.341 336.624 444.027 1.00 107.58 ? 23  ILE B CD1 1 
ATOM 3546 N N   . THR D 4 24  ? 313.070 339.674 442.148 1.00 104.18 ? 24  THR B N   1 
ATOM 3547 C CA  . THR D 4 24  ? 312.955 340.673 441.094 1.00 104.18 ? 24  THR B CA  1 
ATOM 3548 C C   . THR D 4 24  ? 314.230 341.493 440.978 1.00 104.18 ? 24  THR B C   1 
ATOM 3549 O O   . THR D 4 24  ? 314.714 342.039 441.972 1.00 104.18 ? 24  THR B O   1 
ATOM 3550 C CB  . THR D 4 24  ? 311.779 341.604 441.365 1.00 104.18 ? 24  THR B CB  1 
ATOM 3551 O OG1 . THR D 4 24  ? 311.800 341.989 442.743 1.00 104.18 ? 24  THR B OG1 1 
ATOM 3552 C CG2 . THR D 4 24  ? 310.468 340.908 441.065 1.00 104.18 ? 24  THR B CG2 1 
ATOM 3553 N N   . THR D 4 25  ? 314.762 341.581 439.761 1.00 112.19 ? 25  THR B N   1 
ATOM 3554 C CA  . THR D 4 25  ? 315.889 342.431 439.392 1.00 112.19 ? 25  THR B CA  1 
ATOM 3555 C C   . THR D 4 25  ? 315.444 343.400 438.293 1.00 112.19 ? 25  THR B C   1 
ATOM 3556 O O   . THR D 4 25  ? 314.259 343.499 437.970 1.00 112.19 ? 25  THR B O   1 
ATOM 3557 C CB  . THR D 4 25  ? 317.085 341.597 438.926 1.00 112.19 ? 25  THR B CB  1 
ATOM 3558 O OG1 . THR D 4 25  ? 316.829 341.092 437.609 1.00 112.19 ? 25  THR B OG1 1 
ATOM 3559 C CG2 . THR D 4 25  ? 317.354 340.435 439.869 1.00 112.19 ? 25  THR B CG2 1 
ATOM 3560 N N   . GLN D 4 26  ? 316.403 344.123 437.721 1.00 110.33 ? 26  GLN B N   1 
ATOM 3561 C CA  . GLN D 4 26  ? 316.117 345.016 436.597 1.00 110.33 ? 26  GLN B CA  1 
ATOM 3562 C C   . GLN D 4 26  ? 316.853 344.587 435.332 1.00 110.33 ? 26  GLN B C   1 
ATOM 3563 O O   . GLN D 4 26  ? 317.341 345.425 434.572 1.00 110.33 ? 26  GLN B O   1 
ATOM 3564 C CB  . GLN D 4 26  ? 316.491 346.455 436.940 1.00 110.33 ? 26  GLN B CB  1 
ATOM 3565 C CG  . GLN D 4 26  ? 315.776 347.012 438.145 1.00 110.33 ? 26  GLN B CG  1 
ATOM 3566 C CD  . GLN D 4 26  ? 316.569 346.830 439.416 1.00 110.33 ? 26  GLN B CD  1 
ATOM 3567 O OE1 . GLN D 4 26  ? 317.152 345.773 439.651 1.00 110.33 ? 26  GLN B OE1 1 
ATOM 3568 N NE2 . GLN D 4 26  ? 316.601 347.864 440.245 1.00 110.33 ? 26  GLN B NE2 1 
ATOM 3569 N N   . ASN D 4 30  ? 323.536 344.888 435.700 1.00 111.08 ? 30  ASN B N   1 
ATOM 3570 C CA  . ASN D 4 30  ? 324.861 344.603 435.165 1.00 111.08 ? 30  ASN B CA  1 
ATOM 3571 C C   . ASN D 4 30  ? 325.576 343.553 436.008 1.00 111.08 ? 30  ASN B C   1 
ATOM 3572 O O   . ASN D 4 30  ? 325.887 343.790 437.171 1.00 111.08 ? 30  ASN B O   1 
ATOM 3573 C CB  . ASN D 4 30  ? 325.692 345.881 435.096 1.00 111.08 ? 30  ASN B CB  1 
ATOM 3574 C CG  . ASN D 4 30  ? 326.957 345.703 434.294 1.00 111.08 ? 30  ASN B CG  1 
ATOM 3575 O OD1 . ASN D 4 30  ? 327.074 344.774 433.499 1.00 111.08 ? 30  ASN B OD1 1 
ATOM 3576 N ND2 . ASN D 4 30  ? 327.914 346.598 434.493 1.00 111.08 ? 30  ASN B ND2 1 
ATOM 3577 N N   . VAL D 4 31  ? 325.845 342.395 435.410 1.00 102.40 ? 31  VAL B N   1 
ATOM 3578 C CA  . VAL D 4 31  ? 326.372 341.240 436.125 1.00 102.40 ? 31  VAL B CA  1 
ATOM 3579 C C   . VAL D 4 31  ? 327.811 340.991 435.692 1.00 102.40 ? 31  VAL B C   1 
ATOM 3580 O O   . VAL D 4 31  ? 328.110 340.936 434.494 1.00 102.40 ? 31  VAL B O   1 
ATOM 3581 C CB  . VAL D 4 31  ? 325.485 339.994 435.909 1.00 102.40 ? 31  VAL B CB  1 
ATOM 3582 C CG1 . VAL D 4 31  ? 325.115 339.813 434.450 1.00 102.40 ? 31  VAL B CG1 1 
ATOM 3583 C CG2 . VAL D 4 31  ? 326.161 338.747 436.424 1.00 102.40 ? 31  VAL B CG2 1 
ATOM 3584 N N   . VAL D 4 32  ? 328.709 340.877 436.666 1.00 97.80  ? 32  VAL B N   1 
ATOM 3585 C CA  . VAL D 4 32  ? 330.099 340.517 436.424 1.00 97.80  ? 32  VAL B CA  1 
ATOM 3586 C C   . VAL D 4 32  ? 330.233 339.013 436.605 1.00 97.80  ? 32  VAL B C   1 
ATOM 3587 O O   . VAL D 4 32  ? 329.791 338.456 437.616 1.00 97.80  ? 32  VAL B O   1 
ATOM 3588 C CB  . VAL D 4 32  ? 331.056 341.315 437.330 1.00 97.80  ? 32  VAL B CB  1 
ATOM 3589 C CG1 . VAL D 4 32  ? 330.613 341.304 438.784 1.00 97.80  ? 32  VAL B CG1 1 
ATOM 3590 C CG2 . VAL D 4 32  ? 332.465 340.780 437.211 1.00 97.80  ? 32  VAL B CG2 1 
ATOM 3591 N N   . VAL D 4 33  ? 330.785 338.347 435.599 1.00 101.80 ? 33  VAL B N   1 
ATOM 3592 C CA  . VAL D 4 33  ? 330.774 336.892 435.533 1.00 101.80 ? 33  VAL B CA  1 
ATOM 3593 C C   . VAL D 4 33  ? 332.206 336.380 435.676 1.00 101.80 ? 33  VAL B C   1 
ATOM 3594 O O   . VAL D 4 33  ? 332.994 336.391 434.721 1.00 101.80 ? 33  VAL B O   1 
ATOM 3595 C CB  . VAL D 4 33  ? 330.055 336.392 434.263 1.00 101.80 ? 33  VAL B CB  1 
ATOM 3596 C CG1 . VAL D 4 33  ? 330.482 337.147 432.982 1.00 101.80 ? 33  VAL B CG1 1 
ATOM 3597 C CG2 . VAL D 4 33  ? 330.185 334.880 434.105 1.00 101.80 ? 33  VAL B CG2 1 
ATOM 3598 N N   . GLY D 4 34  ? 332.545 336.000 436.913 1.00 95.01  ? 34  GLY B N   1 
ATOM 3599 C CA  . GLY D 4 34  ? 333.714 335.232 437.312 1.00 95.01  ? 34  GLY B CA  1 
ATOM 3600 C C   . GLY D 4 34  ? 335.037 335.525 436.650 1.00 95.01  ? 34  GLY B C   1 
ATOM 3601 O O   . GLY D 4 34  ? 335.512 336.661 436.650 1.00 95.01  ? 34  GLY B O   1 
ATOM 3602 N N   . TYR D 4 35  ? 335.626 334.496 436.052 1.00 95.48  ? 35  TYR B N   1 
ATOM 3603 C CA  . TYR D 4 35  ? 336.821 334.651 435.241 1.00 95.48  ? 35  TYR B CA  1 
ATOM 3604 C C   . TYR D 4 35  ? 336.533 334.458 433.759 1.00 95.48  ? 35  TYR B C   1 
ATOM 3605 O O   . TYR D 4 35  ? 337.392 333.976 433.014 1.00 95.48  ? 35  TYR B O   1 
ATOM 3606 C CB  . TYR D 4 35  ? 337.898 333.690 435.721 1.00 95.48  ? 35  TYR B CB  1 
ATOM 3607 C CG  . TYR D 4 35  ? 338.473 334.099 437.043 1.00 95.48  ? 35  TYR B CG  1 
ATOM 3608 C CD1 . TYR D 4 35  ? 339.506 335.015 437.112 1.00 95.48  ? 35  TYR B CD1 1 
ATOM 3609 C CD2 . TYR D 4 35  ? 337.976 333.581 438.221 1.00 95.48  ? 35  TYR B CD2 1 
ATOM 3610 C CE1 . TYR D 4 35  ? 340.037 335.396 438.316 1.00 95.48  ? 35  TYR B CE1 1 
ATOM 3611 C CE2 . TYR D 4 35  ? 338.499 333.957 439.431 1.00 95.48  ? 35  TYR B CE2 1 
ATOM 3612 C CZ  . TYR D 4 35  ? 339.529 334.863 439.471 1.00 95.48  ? 35  TYR B CZ  1 
ATOM 3613 O OH  . TYR D 4 35  ? 340.056 335.242 440.679 1.00 95.48  ? 35  TYR B OH  1 
ATOM 3614 N N   . GLY D 4 36  ? 335.332 334.823 433.321 1.00 112.51 ? 36  GLY B N   1 
ATOM 3615 C CA  . GLY D 4 36  ? 334.974 334.817 431.922 1.00 112.51 ? 36  GLY B CA  1 
ATOM 3616 C C   . GLY D 4 36  ? 334.139 333.638 431.475 1.00 112.51 ? 36  GLY B C   1 
ATOM 3617 O O   . GLY D 4 36  ? 333.439 333.750 430.463 1.00 112.51 ? 36  GLY B O   1 
ATOM 3618 N N   . VAL D 4 37  ? 334.172 332.528 432.199 1.00 121.01 ? 37  VAL B N   1 
ATOM 3619 C CA  . VAL D 4 37  ? 333.535 331.299 431.751 1.00 121.01 ? 37  VAL B CA  1 
ATOM 3620 C C   . VAL D 4 37  ? 332.202 331.122 432.472 1.00 121.01 ? 37  VAL B C   1 
ATOM 3621 O O   . VAL D 4 37  ? 332.064 331.406 433.668 1.00 121.01 ? 37  VAL B O   1 
ATOM 3622 C CB  . VAL D 4 37  ? 334.487 330.089 431.939 1.00 121.01 ? 37  VAL B CB  1 
ATOM 3623 C CG1 . VAL D 4 37  ? 334.879 329.881 433.400 1.00 121.01 ? 37  VAL B CG1 1 
ATOM 3624 C CG2 . VAL D 4 37  ? 333.902 328.814 431.336 1.00 121.01 ? 37  VAL B CG2 1 
ATOM 3625 N N   . TRP D 4 38  ? 331.194 330.710 431.710 1.00 131.69 ? 38  TRP B N   1 
ATOM 3626 C CA  . TRP D 4 38  ? 329.908 330.394 432.306 1.00 131.69 ? 38  TRP B CA  1 
ATOM 3627 C C   . TRP D 4 38  ? 329.952 329.015 432.947 1.00 131.69 ? 38  TRP B C   1 
ATOM 3628 O O   . TRP D 4 38  ? 330.568 328.098 432.394 1.00 131.69 ? 38  TRP B O   1 
ATOM 3629 C CB  . TRP D 4 38  ? 328.802 330.423 431.254 1.00 131.69 ? 38  TRP B CB  1 
ATOM 3630 C CG  . TRP D 4 38  ? 327.509 330.912 431.788 1.00 131.69 ? 38  TRP B CG  1 
ATOM 3631 C CD1 . TRP D 4 38  ? 326.494 330.159 432.293 1.00 131.69 ? 38  TRP B CD1 1 
ATOM 3632 C CD2 . TRP D 4 38  ? 327.086 332.273 431.878 1.00 131.69 ? 38  TRP B CD2 1 
ATOM 3633 N NE1 . TRP D 4 38  ? 325.462 330.968 432.694 1.00 131.69 ? 38  TRP B NE1 1 
ATOM 3634 C CE2 . TRP D 4 38  ? 325.801 332.272 432.448 1.00 131.69 ? 38  TRP B CE2 1 
ATOM 3635 C CE3 . TRP D 4 38  ? 327.669 333.494 431.529 1.00 131.69 ? 38  TRP B CE3 1 
ATOM 3636 C CZ2 . TRP D 4 38  ? 325.087 333.444 432.679 1.00 131.69 ? 38  TRP B CZ2 1 
ATOM 3637 C CZ3 . TRP D 4 38  ? 326.961 334.655 431.756 1.00 131.69 ? 38  TRP B CZ3 1 
ATOM 3638 C CH2 . TRP D 4 38  ? 325.683 334.623 432.326 1.00 131.69 ? 38  TRP B CH2 1 
ATOM 3639 N N   . PRO D 4 39  ? 329.321 328.848 434.110 1.00 133.45 ? 39  PRO B N   1 
ATOM 3640 C CA  . PRO D 4 39  ? 329.362 327.551 434.797 1.00 133.45 ? 39  PRO B CA  1 
ATOM 3641 C C   . PRO D 4 39  ? 328.570 326.491 434.047 1.00 133.45 ? 39  PRO B C   1 
ATOM 3642 O O   . PRO D 4 39  ? 327.414 326.701 433.677 1.00 133.45 ? 39  PRO B O   1 
ATOM 3643 C CB  . PRO D 4 39  ? 328.736 327.854 436.162 1.00 133.45 ? 39  PRO B CB  1 
ATOM 3644 C CG  . PRO D 4 39  ? 328.885 329.310 436.331 1.00 133.45 ? 39  PRO B CG  1 
ATOM 3645 C CD  . PRO D 4 39  ? 328.739 329.890 434.965 1.00 133.45 ? 39  PRO B CD  1 
ATOM 3646 N N   . GLU D 4 40  ? 329.209 325.346 433.828 1.00 150.46 ? 40  GLU B N   1 
ATOM 3647 C CA  . GLU D 4 40  ? 328.601 324.225 433.131 1.00 150.46 ? 40  GLU B CA  1 
ATOM 3648 C C   . GLU D 4 40  ? 328.997 322.937 433.838 1.00 150.46 ? 40  GLU B C   1 
ATOM 3649 O O   . GLU D 4 40  ? 329.880 322.920 434.699 1.00 150.46 ? 40  GLU B O   1 
ATOM 3650 C CB  . GLU D 4 40  ? 329.021 324.184 431.656 1.00 150.46 ? 40  GLU B CB  1 
ATOM 3651 C CG  . GLU D 4 40  ? 328.273 325.159 430.761 1.00 150.46 ? 40  GLU B CG  1 
ATOM 3652 C CD  . GLU D 4 40  ? 328.503 324.895 429.286 1.00 150.46 ? 40  GLU B CD  1 
ATOM 3653 O OE1 . GLU D 4 40  ? 327.679 325.347 428.464 1.00 150.46 ? 40  GLU B OE1 1 
ATOM 3654 O OE2 . GLU D 4 40  ? 329.507 324.237 428.947 1.00 150.46 ? 40  GLU B OE2 1 
ATOM 3655 N N   . TYR D 4 41  ? 328.341 321.849 433.452 1.00 159.07 ? 41  TYR B N   1 
ATOM 3656 C CA  . TYR D 4 41  ? 328.605 320.538 434.031 1.00 159.07 ? 41  TYR B CA  1 
ATOM 3657 C C   . TYR D 4 41  ? 329.859 319.939 433.392 1.00 159.07 ? 41  TYR B C   1 
ATOM 3658 O O   . TYR D 4 41  ? 330.613 320.603 432.675 1.00 159.07 ? 41  TYR B O   1 
ATOM 3659 C CB  . TYR D 4 41  ? 327.397 319.624 433.847 1.00 159.07 ? 41  TYR B CB  1 
ATOM 3660 C CG  . TYR D 4 41  ? 326.149 320.039 434.596 1.00 159.07 ? 41  TYR B CG  1 
ATOM 3661 C CD1 . TYR D 4 41  ? 325.252 320.951 434.048 1.00 159.07 ? 41  TYR B CD1 1 
ATOM 3662 C CD2 . TYR D 4 41  ? 325.857 319.504 435.843 1.00 159.07 ? 41  TYR B CD2 1 
ATOM 3663 C CE1 . TYR D 4 41  ? 324.103 321.326 434.729 1.00 159.07 ? 41  TYR B CE1 1 
ATOM 3664 C CE2 . TYR D 4 41  ? 324.707 319.868 436.529 1.00 159.07 ? 41  TYR B CE2 1 
ATOM 3665 C CZ  . TYR D 4 41  ? 323.838 320.781 435.968 1.00 159.07 ? 41  TYR B CZ  1 
ATOM 3666 O OH  . TYR D 4 41  ? 322.701 321.151 436.646 1.00 159.07 ? 41  TYR B OH  1 
ATOM 3667 N N   . LEU D 4 42  ? 330.091 318.657 433.650 1.00 155.14 ? 42  LEU B N   1 
ATOM 3668 C CA  . LEU D 4 42  ? 331.233 317.948 433.084 1.00 155.14 ? 42  LEU B CA  1 
ATOM 3669 C C   . LEU D 4 42  ? 331.072 317.713 431.582 1.00 155.14 ? 42  LEU B C   1 
ATOM 3670 O O   . LEU D 4 42  ? 331.893 317.042 430.955 1.00 155.14 ? 42  LEU B O   1 
ATOM 3671 C CB  . LEU D 4 42  ? 331.441 316.625 433.831 1.00 155.14 ? 42  LEU B CB  1 
ATOM 3672 C CG  . LEU D 4 42  ? 330.299 315.605 433.935 1.00 155.14 ? 42  LEU B CG  1 
ATOM 3673 C CD1 . LEU D 4 42  ? 330.296 314.563 432.816 1.00 155.14 ? 42  LEU B CD1 1 
ATOM 3674 C CD2 . LEU D 4 42  ? 330.339 314.934 435.292 1.00 155.14 ? 42  LEU B CD2 1 
ATOM 3675 N N   . ASP D 4 51  ? 333.390 306.508 439.079 1.00 180.77 ? 51  ASP B N   1 
ATOM 3676 C CA  . ASP D 4 51  ? 331.970 306.191 439.181 1.00 180.77 ? 51  ASP B CA  1 
ATOM 3677 C C   . ASP D 4 51  ? 331.107 307.181 438.407 1.00 180.77 ? 51  ASP B C   1 
ATOM 3678 O O   . ASP D 4 51  ? 331.623 308.035 437.687 1.00 180.77 ? 51  ASP B O   1 
ATOM 3679 C CB  . ASP D 4 51  ? 331.541 306.144 440.649 1.00 180.77 ? 51  ASP B CB  1 
ATOM 3680 C CG  . ASP D 4 51  ? 332.063 307.321 441.455 1.00 180.77 ? 51  ASP B CG  1 
ATOM 3681 O OD1 . ASP D 4 51  ? 332.656 308.251 440.869 1.00 180.77 ? 51  ASP B OD1 1 
ATOM 3682 O OD2 . ASP D 4 51  ? 331.884 307.311 442.690 1.00 180.77 ? 51  ASP B OD2 1 
ATOM 3683 N N   . GLN D 4 52  ? 329.789 307.064 438.563 1.00 189.52 ? 52  GLN B N   1 
ATOM 3684 C CA  . GLN D 4 52  ? 328.874 307.900 437.809 1.00 189.52 ? 52  GLN B CA  1 
ATOM 3685 C C   . GLN D 4 52  ? 328.233 308.946 438.711 1.00 189.52 ? 52  GLN B C   1 
ATOM 3686 O O   . GLN D 4 52  ? 327.612 308.596 439.721 1.00 189.52 ? 52  GLN B O   1 
ATOM 3687 C CB  . GLN D 4 52  ? 327.775 307.056 437.147 1.00 189.52 ? 52  GLN B CB  1 
ATOM 3688 C CG  . GLN D 4 52  ? 327.018 307.780 436.046 1.00 189.52 ? 52  GLN B CG  1 
ATOM 3689 C CD  . GLN D 4 52  ? 326.620 306.862 434.905 1.00 189.52 ? 52  GLN B CD  1 
ATOM 3690 O OE1 . GLN D 4 52  ? 326.739 305.640 435.004 1.00 189.52 ? 52  GLN B OE1 1 
ATOM 3691 N NE2 . GLN D 4 52  ? 326.144 307.448 433.814 1.00 189.52 ? 52  GLN B NE2 1 
ATOM 3692 N N   . PRO D 4 53  ? 328.366 310.231 438.380 1.00 184.56 ? 53  PRO B N   1 
ATOM 3693 C CA  . PRO D 4 53  ? 327.710 311.272 439.180 1.00 184.56 ? 53  PRO B CA  1 
ATOM 3694 C C   . PRO D 4 53  ? 326.305 311.591 438.685 1.00 184.56 ? 53  PRO B C   1 
ATOM 3695 O O   . PRO D 4 53  ? 325.990 311.375 437.511 1.00 184.56 ? 53  PRO B O   1 
ATOM 3696 C CB  . PRO D 4 53  ? 328.651 312.468 439.016 1.00 184.56 ? 53  PRO B CB  1 
ATOM 3697 C CG  . PRO D 4 53  ? 329.248 312.278 437.669 1.00 184.56 ? 53  PRO B CG  1 
ATOM 3698 C CD  . PRO D 4 53  ? 329.279 310.800 437.374 1.00 184.56 ? 53  PRO B CD  1 
ATOM 3699 N N   . THR D 4 54  ? 325.452 312.096 439.573 1.00 173.24 ? 54  THR B N   1 
ATOM 3700 C CA  . THR D 4 54  ? 324.087 312.472 439.237 1.00 173.24 ? 54  THR B CA  1 
ATOM 3701 C C   . THR D 4 54  ? 323.935 313.987 439.264 1.00 173.24 ? 54  THR B C   1 
ATOM 3702 O O   . THR D 4 54  ? 324.680 314.690 439.949 1.00 173.24 ? 54  THR B O   1 
ATOM 3703 C CB  . THR D 4 54  ? 323.078 311.820 440.192 1.00 173.24 ? 54  THR B CB  1 
ATOM 3704 O OG1 . THR D 4 54  ? 321.746 312.174 439.801 1.00 173.24 ? 54  THR B OG1 1 
ATOM 3705 C CG2 . THR D 4 54  ? 323.323 312.242 441.636 1.00 173.24 ? 54  THR B CG2 1 
ATOM 3706 N N   . GLN D 4 55  ? 322.972 314.489 438.495 1.00 165.20 ? 55  GLN B N   1 
ATOM 3707 C CA  . GLN D 4 55  ? 322.758 315.930 438.345 1.00 165.20 ? 55  GLN B CA  1 
ATOM 3708 C C   . GLN D 4 55  ? 321.347 316.339 438.761 1.00 165.20 ? 55  GLN B C   1 
ATOM 3709 O O   . GLN D 4 55  ? 320.456 316.505 437.908 1.00 165.20 ? 55  GLN B O   1 
ATOM 3710 C CB  . GLN D 4 55  ? 323.087 316.364 436.911 1.00 165.20 ? 55  GLN B CB  1 
ATOM 3711 C CG  . GLN D 4 55  ? 322.551 315.480 435.771 1.00 165.20 ? 55  GLN B CG  1 
ATOM 3712 C CD  . GLN D 4 55  ? 323.013 315.947 434.400 1.00 165.20 ? 55  GLN B CD  1 
ATOM 3713 O OE1 . GLN D 4 55  ? 323.686 316.970 434.272 1.00 165.20 ? 55  GLN B OE1 1 
ATOM 3714 N NE2 . GLN D 4 55  ? 322.656 315.194 433.367 1.00 165.20 ? 55  GLN B NE2 1 
ATOM 3715 N N   . PRO D 4 56  ? 321.096 316.536 440.056 1.00 162.20 ? 56  PRO B N   1 
ATOM 3716 C CA  . PRO D 4 56  ? 319.740 316.872 440.505 1.00 162.20 ? 56  PRO B CA  1 
ATOM 3717 C C   . PRO D 4 56  ? 319.402 318.339 440.287 1.00 162.20 ? 56  PRO B C   1 
ATOM 3718 O O   . PRO D 4 56  ? 320.181 319.245 440.593 1.00 162.20 ? 56  PRO B O   1 
ATOM 3719 C CB  . PRO D 4 56  ? 319.774 316.525 442.000 1.00 162.20 ? 56  PRO B CB  1 
ATOM 3720 C CG  . PRO D 4 56  ? 321.188 316.654 442.387 1.00 162.20 ? 56  PRO B CG  1 
ATOM 3721 C CD  . PRO D 4 56  ? 322.046 316.429 441.177 1.00 162.20 ? 56  PRO B CD  1 
ATOM 3722 N N   . ASP D 4 57  ? 318.203 318.563 439.746 1.00 159.54 ? 57  ASP B N   1 
ATOM 3723 C CA  . ASP D 4 57  ? 317.774 319.884 439.307 1.00 159.54 ? 57  ASP B CA  1 
ATOM 3724 C C   . ASP D 4 57  ? 316.441 320.321 439.896 1.00 159.54 ? 57  ASP B C   1 
ATOM 3725 O O   . ASP D 4 57  ? 316.260 321.520 440.135 1.00 159.54 ? 57  ASP B O   1 
ATOM 3726 C CB  . ASP D 4 57  ? 317.673 319.917 437.771 1.00 159.54 ? 57  ASP B CB  1 
ATOM 3727 C CG  . ASP D 4 57  ? 317.819 321.316 437.185 1.00 159.54 ? 57  ASP B CG  1 
ATOM 3728 O OD1 . ASP D 4 57  ? 317.874 322.308 437.938 1.00 159.54 ? 57  ASP B OD1 1 
ATOM 3729 O OD2 . ASP D 4 57  ? 317.915 321.417 435.945 1.00 159.54 ? 57  ASP B OD2 1 
ATOM 3730 N N   . VAL D 4 58  ? 315.517 319.400 440.170 1.00 153.97 ? 58  VAL B N   1 
ATOM 3731 C CA  . VAL D 4 58  ? 314.165 319.804 440.538 1.00 153.97 ? 58  VAL B CA  1 
ATOM 3732 C C   . VAL D 4 58  ? 314.028 320.188 442.008 1.00 153.97 ? 58  VAL B C   1 
ATOM 3733 O O   . VAL D 4 58  ? 313.096 320.922 442.359 1.00 153.97 ? 58  VAL B O   1 
ATOM 3734 C CB  . VAL D 4 58  ? 313.160 318.694 440.184 1.00 153.97 ? 58  VAL B CB  1 
ATOM 3735 C CG1 . VAL D 4 58  ? 313.124 318.482 438.685 1.00 153.97 ? 58  VAL B CG1 1 
ATOM 3736 C CG2 . VAL D 4 58  ? 313.524 317.395 440.885 1.00 153.97 ? 58  VAL B CG2 1 
ATOM 3737 N N   . ALA D 4 59  ? 314.918 319.726 442.881 1.00 138.04 ? 59  ALA B N   1 
ATOM 3738 C CA  . ALA D 4 59  ? 314.745 319.937 444.308 1.00 138.04 ? 59  ALA B CA  1 
ATOM 3739 C C   . ALA D 4 59  ? 315.747 320.904 444.918 1.00 138.04 ? 59  ALA B C   1 
ATOM 3740 O O   . ALA D 4 59  ? 315.630 321.217 446.108 1.00 138.04 ? 59  ALA B O   1 
ATOM 3741 C CB  . ALA D 4 59  ? 314.820 318.596 445.048 1.00 138.04 ? 59  ALA B CB  1 
ATOM 3742 N N   . THR D 4 60  ? 316.727 321.386 444.153 1.00 128.79 ? 60  THR B N   1 
ATOM 3743 C CA  . THR D 4 60  ? 317.798 322.200 444.709 1.00 128.79 ? 60  THR B CA  1 
ATOM 3744 C C   . THR D 4 60  ? 317.870 323.609 444.147 1.00 128.79 ? 60  THR B C   1 
ATOM 3745 O O   . THR D 4 60  ? 318.173 324.536 444.902 1.00 128.79 ? 60  THR B O   1 
ATOM 3746 C CB  . THR D 4 60  ? 319.161 321.526 444.487 1.00 128.79 ? 60  THR B CB  1 
ATOM 3747 O OG1 . THR D 4 60  ? 319.453 321.481 443.084 1.00 128.79 ? 60  THR B OG1 1 
ATOM 3748 C CG2 . THR D 4 60  ? 319.176 320.114 445.062 1.00 128.79 ? 60  THR B CG2 1 
ATOM 3749 N N   . CYS D 4 61  ? 317.600 323.797 442.855 1.00 121.28 ? 61  CYS B N   1 
ATOM 3750 C CA  . CYS D 4 61  ? 317.779 325.097 442.210 1.00 121.28 ? 61  CYS B CA  1 
ATOM 3751 C C   . CYS D 4 61  ? 316.663 326.026 442.670 1.00 121.28 ? 61  CYS B C   1 
ATOM 3752 O O   . CYS D 4 61  ? 315.580 326.096 442.089 1.00 121.28 ? 61  CYS B O   1 
ATOM 3753 C CB  . CYS D 4 61  ? 317.801 324.951 440.695 1.00 121.28 ? 61  CYS B CB  1 
ATOM 3754 S SG  . CYS D 4 61  ? 319.367 324.369 440.010 1.00 121.28 ? 61  CYS B SG  1 
ATOM 3755 N N   . ARG D 4 62  ? 316.936 326.732 443.760 1.00 105.32 ? 62  ARG B N   1 
ATOM 3756 C CA  . ARG D 4 62  ? 316.029 327.751 444.254 1.00 105.32 ? 62  ARG B CA  1 
ATOM 3757 C C   . ARG D 4 62  ? 316.851 328.827 444.941 1.00 105.32 ? 62  ARG B C   1 
ATOM 3758 O O   . ARG D 4 62  ? 317.973 328.592 445.390 1.00 105.32 ? 62  ARG B O   1 
ATOM 3759 C CB  . ARG D 4 62  ? 314.980 327.160 445.198 1.00 105.32 ? 62  ARG B CB  1 
ATOM 3760 C CG  . ARG D 4 62  ? 315.500 326.817 446.568 1.00 105.32 ? 62  ARG B CG  1 
ATOM 3761 C CD  . ARG D 4 62  ? 314.572 325.866 447.275 1.00 105.32 ? 62  ARG B CD  1 
ATOM 3762 N NE  . ARG D 4 62  ? 313.228 326.410 447.400 1.00 105.32 ? 62  ARG B NE  1 
ATOM 3763 C CZ  . ARG D 4 62  ? 312.823 327.152 448.421 1.00 105.32 ? 62  ARG B CZ  1 
ATOM 3764 N NH1 . ARG D 4 62  ? 313.661 327.440 449.404 1.00 105.32 ? 62  ARG B NH1 1 
ATOM 3765 N NH2 . ARG D 4 62  ? 311.582 327.606 448.464 1.00 105.32 ? 62  ARG B NH2 1 
ATOM 3766 N N   . PHE D 4 63  ? 316.286 330.022 445.008 1.00 101.88 ? 63  PHE B N   1 
ATOM 3767 C CA  . PHE D 4 63  ? 316.970 331.163 445.593 1.00 101.88 ? 63  PHE B CA  1 
ATOM 3768 C C   . PHE D 4 63  ? 316.848 331.085 447.107 1.00 101.88 ? 63  PHE B C   1 
ATOM 3769 O O   . PHE D 4 63  ? 315.829 331.487 447.673 1.00 101.88 ? 63  PHE B O   1 
ATOM 3770 C CB  . PHE D 4 63  ? 316.376 332.464 445.074 1.00 101.88 ? 63  PHE B CB  1 
ATOM 3771 C CG  . PHE D 4 63  ? 316.743 332.775 443.665 1.00 101.88 ? 63  PHE B CG  1 
ATOM 3772 C CD1 . PHE D 4 63  ? 317.902 333.465 443.379 1.00 101.88 ? 63  PHE B CD1 1 
ATOM 3773 C CD2 . PHE D 4 63  ? 315.923 332.390 442.625 1.00 101.88 ? 63  PHE B CD2 1 
ATOM 3774 C CE1 . PHE D 4 63  ? 318.243 333.764 442.079 1.00 101.88 ? 63  PHE B CE1 1 
ATOM 3775 C CE2 . PHE D 4 63  ? 316.258 332.686 441.323 1.00 101.88 ? 63  PHE B CE2 1 
ATOM 3776 C CZ  . PHE D 4 63  ? 317.420 333.371 441.050 1.00 101.88 ? 63  PHE B CZ  1 
ATOM 3777 N N   . TYR D 4 64  ? 317.883 330.584 447.765 1.00 100.71 ? 64  TYR B N   1 
ATOM 3778 C CA  . TYR D 4 64  ? 317.917 330.562 449.223 1.00 100.71 ? 64  TYR B CA  1 
ATOM 3779 C C   . TYR D 4 64  ? 318.261 331.962 449.696 1.00 100.71 ? 64  TYR B C   1 
ATOM 3780 O O   . TYR D 4 64  ? 319.398 332.412 449.557 1.00 100.71 ? 64  TYR B O   1 
ATOM 3781 C CB  . TYR D 4 64  ? 318.932 329.549 449.726 1.00 100.71 ? 64  TYR B CB  1 
ATOM 3782 C CG  . TYR D 4 64  ? 318.561 328.131 449.425 1.00 100.71 ? 64  TYR B CG  1 
ATOM 3783 C CD1 . TYR D 4 64  ? 317.673 327.445 450.232 1.00 100.71 ? 64  TYR B CD1 1 
ATOM 3784 C CD2 . TYR D 4 64  ? 319.096 327.478 448.331 1.00 100.71 ? 64  TYR B CD2 1 
ATOM 3785 C CE1 . TYR D 4 64  ? 317.329 326.144 449.959 1.00 100.71 ? 64  TYR B CE1 1 
ATOM 3786 C CE2 . TYR D 4 64  ? 318.760 326.178 448.050 1.00 100.71 ? 64  TYR B CE2 1 
ATOM 3787 C CZ  . TYR D 4 64  ? 317.876 325.516 448.867 1.00 100.71 ? 64  TYR B CZ  1 
ATOM 3788 O OH  . TYR D 4 64  ? 317.539 324.215 448.589 1.00 100.71 ? 64  TYR B OH  1 
ATOM 3789 N N   . THR D 4 65  ? 317.280 332.662 450.249 1.00 92.97  ? 65  THR B N   1 
ATOM 3790 C CA  . THR D 4 65  ? 317.507 334.012 450.745 1.00 92.97  ? 65  THR B CA  1 
ATOM 3791 C C   . THR D 4 65  ? 318.007 333.937 452.180 1.00 92.97  ? 65  THR B C   1 
ATOM 3792 O O   . THR D 4 65  ? 317.285 333.484 453.072 1.00 92.97  ? 65  THR B O   1 
ATOM 3793 C CB  . THR D 4 65  ? 316.231 334.837 450.655 1.00 92.97  ? 65  THR B CB  1 
ATOM 3794 O OG1 . THR D 4 65  ? 315.906 335.054 449.280 1.00 92.97  ? 65  THR B OG1 1 
ATOM 3795 C CG2 . THR D 4 65  ? 316.423 336.175 451.330 1.00 92.97  ? 65  THR B CG2 1 
ATOM 3796 N N   . LEU D 4 66  ? 319.240 334.379 452.406 1.00 90.39  ? 66  LEU B N   1 
ATOM 3797 C CA  . LEU D 4 66  ? 319.786 334.421 453.751 1.00 90.39  ? 66  LEU B CA  1 
ATOM 3798 C C   . LEU D 4 66  ? 319.124 335.527 454.558 1.00 90.39  ? 66  LEU B C   1 
ATOM 3799 O O   . LEU D 4 66  ? 318.419 336.383 454.023 1.00 90.39  ? 66  LEU B O   1 
ATOM 3800 C CB  . LEU D 4 66  ? 321.291 334.654 453.716 1.00 90.39  ? 66  LEU B CB  1 
ATOM 3801 C CG  . LEU D 4 66  ? 322.155 333.552 453.118 1.00 90.39  ? 66  LEU B CG  1 
ATOM 3802 C CD1 . LEU D 4 66  ? 323.609 333.803 453.443 1.00 90.39  ? 66  LEU B CD1 1 
ATOM 3803 C CD2 . LEU D 4 66  ? 321.727 332.201 453.637 1.00 90.39  ? 66  LEU B CD2 1 
ATOM 3804 N N   . GLU D 4 67  ? 319.364 335.511 455.862 1.00 95.26  ? 67  GLU B N   1 
ATOM 3805 C CA  . GLU D 4 67  ? 318.774 336.561 456.670 1.00 95.26  ? 67  GLU B CA  1 
ATOM 3806 C C   . GLU D 4 67  ? 319.605 337.831 456.555 1.00 95.26  ? 67  GLU B C   1 
ATOM 3807 O O   . GLU D 4 67  ? 320.794 337.805 456.234 1.00 95.26  ? 67  GLU B O   1 
ATOM 3808 C CB  . GLU D 4 67  ? 318.632 336.127 458.126 1.00 95.26  ? 67  GLU B CB  1 
ATOM 3809 C CG  . GLU D 4 67  ? 319.868 336.260 458.970 1.00 95.26  ? 67  GLU B CG  1 
ATOM 3810 C CD  . GLU D 4 67  ? 319.642 335.733 460.370 1.00 95.26  ? 67  GLU B CD  1 
ATOM 3811 O OE1 . GLU D 4 67  ? 318.702 334.933 460.554 1.00 95.26  ? 67  GLU B OE1 1 
ATOM 3812 O OE2 . GLU D 4 67  ? 320.391 336.123 461.290 1.00 95.26  ? 67  GLU B OE2 1 
ATOM 3813 N N   . SER D 4 68  ? 318.948 338.957 456.795 1.00 86.80  ? 68  SER B N   1 
ATOM 3814 C CA  . SER D 4 68  ? 319.525 340.250 456.477 1.00 86.80  ? 68  SER B CA  1 
ATOM 3815 C C   . SER D 4 68  ? 320.332 340.792 457.644 1.00 86.80  ? 68  SER B C   1 
ATOM 3816 O O   . SER D 4 68  ? 319.962 340.619 458.807 1.00 86.80  ? 68  SER B O   1 
ATOM 3817 C CB  . SER D 4 68  ? 318.424 341.236 456.117 1.00 86.80  ? 68  SER B CB  1 
ATOM 3818 O OG  . SER D 4 68  ? 317.912 341.833 457.290 1.00 86.80  ? 68  SER B OG  1 
ATOM 3819 N N   . VAL D 4 69  ? 321.434 341.455 457.324 1.00 81.61  ? 69  VAL B N   1 
ATOM 3820 C CA  . VAL D 4 69  ? 322.274 342.087 458.318 1.00 81.61  ? 69  VAL B CA  1 
ATOM 3821 C C   . VAL D 4 69  ? 322.012 343.581 458.293 1.00 81.61  ? 69  VAL B C   1 
ATOM 3822 O O   . VAL D 4 69  ? 321.550 344.143 457.300 1.00 81.61  ? 69  VAL B O   1 
ATOM 3823 C CB  . VAL D 4 69  ? 323.762 341.792 458.082 1.00 81.61  ? 69  VAL B CB  1 
ATOM 3824 C CG1 . VAL D 4 69  ? 324.045 340.344 458.352 1.00 81.61  ? 69  VAL B CG1 1 
ATOM 3825 C CG2 . VAL D 4 69  ? 324.124 342.133 456.667 1.00 81.61  ? 69  VAL B CG2 1 
ATOM 3826 N N   . GLN D 4 70  ? 322.316 344.237 459.402 1.00 89.17  ? 70  GLN B N   1 
ATOM 3827 C CA  . GLN D 4 70  ? 322.059 345.657 459.562 1.00 89.17  ? 70  GLN B CA  1 
ATOM 3828 C C   . GLN D 4 70  ? 323.369 346.417 459.498 1.00 89.17  ? 70  GLN B C   1 
ATOM 3829 O O   . GLN D 4 70  ? 324.313 346.094 460.222 1.00 89.17  ? 70  GLN B O   1 
ATOM 3830 C CB  . GLN D 4 70  ? 321.358 345.936 460.886 1.00 89.17  ? 70  GLN B CB  1 
ATOM 3831 C CG  . GLN D 4 70  ? 319.934 345.477 460.911 1.00 89.17  ? 70  GLN B CG  1 
ATOM 3832 C CD  . GLN D 4 70  ? 319.069 346.383 461.738 1.00 89.17  ? 70  GLN B CD  1 
ATOM 3833 O OE1 . GLN D 4 70  ? 319.556 347.325 462.360 1.00 89.17  ? 70  GLN B OE1 1 
ATOM 3834 N NE2 . GLN D 4 70  ? 317.773 346.113 461.748 1.00 89.17  ? 70  GLN B NE2 1 
ATOM 3835 N N   . TRP D 4 71  ? 323.418 347.426 458.648 1.00 83.84  ? 71  TRP B N   1 
ATOM 3836 C CA  . TRP D 4 71  ? 324.617 348.222 458.442 1.00 83.84  ? 71  TRP B CA  1 
ATOM 3837 C C   . TRP D 4 71  ? 324.494 349.474 459.295 1.00 83.84  ? 71  TRP B C   1 
ATOM 3838 O O   . TRP D 4 71  ? 323.787 350.413 458.926 1.00 83.84  ? 71  TRP B O   1 
ATOM 3839 C CB  . TRP D 4 71  ? 324.767 348.552 456.961 1.00 83.84  ? 71  TRP B CB  1 
ATOM 3840 C CG  . TRP D 4 71  ? 325.949 349.362 456.571 1.00 83.84  ? 71  TRP B CG  1 
ATOM 3841 C CD1 . TRP D 4 71  ? 327.060 349.615 457.308 1.00 83.84  ? 71  TRP B CD1 1 
ATOM 3842 C CD2 . TRP D 4 71  ? 326.143 350.010 455.319 1.00 83.84  ? 71  TRP B CD2 1 
ATOM 3843 N NE1 . TRP D 4 71  ? 327.930 350.396 456.597 1.00 83.84  ? 71  TRP B NE1 1 
ATOM 3844 C CE2 . TRP D 4 71  ? 327.386 350.650 455.369 1.00 83.84  ? 71  TRP B CE2 1 
ATOM 3845 C CE3 . TRP D 4 71  ? 325.382 350.115 454.162 1.00 83.84  ? 71  TRP B CE3 1 
ATOM 3846 C CZ2 . TRP D 4 71  ? 327.882 351.381 454.311 1.00 83.84  ? 71  TRP B CZ2 1 
ATOM 3847 C CZ3 . TRP D 4 71  ? 325.876 350.838 453.116 1.00 83.84  ? 71  TRP B CZ3 1 
ATOM 3848 C CH2 . TRP D 4 71  ? 327.111 351.466 453.194 1.00 83.84  ? 71  TRP B CH2 1 
ATOM 3849 N N   . MET D 4 72  ? 325.188 349.495 460.423 1.00 92.20  ? 72  MET B N   1 
ATOM 3850 C CA  . MET D 4 72  ? 325.174 350.640 461.313 1.00 92.20  ? 72  MET B CA  1 
ATOM 3851 C C   . MET D 4 72  ? 326.155 351.693 460.812 1.00 92.20  ? 72  MET B C   1 
ATOM 3852 O O   . MET D 4 72  ? 326.707 351.585 459.717 1.00 92.20  ? 72  MET B O   1 
ATOM 3853 C CB  . MET D 4 72  ? 325.490 350.199 462.738 1.00 92.20  ? 72  MET B CB  1 
ATOM 3854 C CG  . MET D 4 72  ? 324.268 349.798 463.518 1.00 92.20  ? 72  MET B CG  1 
ATOM 3855 S SD  . MET D 4 72  ? 323.209 351.225 463.806 1.00 92.20  ? 72  MET B SD  1 
ATOM 3856 C CE  . MET D 4 72  ? 321.754 350.453 464.506 1.00 92.20  ? 72  MET B CE  1 
ATOM 3857 N N   . LYS D 4 73  ? 326.376 352.732 461.616 1.00 92.46  ? 73  LYS B N   1 
ATOM 3858 C CA  . LYS D 4 73  ? 327.300 353.787 461.215 1.00 92.46  ? 73  LYS B CA  1 
ATOM 3859 C C   . LYS D 4 73  ? 328.741 353.308 461.270 1.00 92.46  ? 73  LYS B C   1 
ATOM 3860 O O   . LYS D 4 73  ? 329.465 353.362 460.273 1.00 92.46  ? 73  LYS B O   1 
ATOM 3861 C CB  . LYS D 4 73  ? 327.117 355.019 462.096 1.00 92.46  ? 73  LYS B CB  1 
ATOM 3862 C CG  . LYS D 4 73  ? 326.016 355.937 461.632 1.00 92.46  ? 73  LYS B CG  1 
ATOM 3863 C CD  . LYS D 4 73  ? 325.887 357.166 462.516 1.00 92.46  ? 73  LYS B CD  1 
ATOM 3864 C CE  . LYS D 4 73  ? 327.104 358.073 462.405 1.00 92.46  ? 73  LYS B CE  1 
ATOM 3865 N NZ  . LYS D 4 73  ? 327.197 358.743 461.083 1.00 92.46  ? 73  LYS B NZ  1 
ATOM 3866 N N   . ASN D 4 74  ? 329.180 352.846 462.432 1.00 106.17 ? 74  ASN B N   1 
ATOM 3867 C CA  . ASN D 4 74  ? 330.561 352.411 462.612 1.00 106.17 ? 74  ASN B CA  1 
ATOM 3868 C C   . ASN D 4 74  ? 330.719 350.911 462.397 1.00 106.17 ? 74  ASN B C   1 
ATOM 3869 O O   . ASN D 4 74  ? 331.297 350.208 463.220 1.00 106.17 ? 74  ASN B O   1 
ATOM 3870 C CB  . ASN D 4 74  ? 331.031 352.810 464.000 1.00 106.17 ? 74  ASN B CB  1 
ATOM 3871 C CG  . ASN D 4 74  ? 330.083 352.344 465.075 1.00 106.17 ? 74  ASN B CG  1 
ATOM 3872 O OD1 . ASN D 4 74  ? 328.995 352.891 465.239 1.00 106.17 ? 74  ASN B OD1 1 
ATOM 3873 N ND2 . ASN D 4 74  ? 330.481 351.312 465.801 1.00 106.17 ? 74  ASN B ND2 1 
ATOM 3874 N N   . SER D 4 75  ? 330.225 350.400 461.280 1.00 94.39  ? 75  SER B N   1 
ATOM 3875 C CA  . SER D 4 75  ? 330.300 348.969 461.052 1.00 94.39  ? 75  SER B CA  1 
ATOM 3876 C C   . SER D 4 75  ? 331.682 348.590 460.542 1.00 94.39  ? 75  SER B C   1 
ATOM 3877 O O   . SER D 4 75  ? 332.522 349.444 460.261 1.00 94.39  ? 75  SER B O   1 
ATOM 3878 C CB  . SER D 4 75  ? 329.231 348.520 460.066 1.00 94.39  ? 75  SER B CB  1 
ATOM 3879 O OG  . SER D 4 75  ? 329.292 347.120 459.895 1.00 94.39  ? 75  SER B OG  1 
ATOM 3880 N N   . ALA D 4 76  ? 331.916 347.292 460.435 1.00 87.41  ? 76  ALA B N   1 
ATOM 3881 C CA  . ALA D 4 76  ? 333.228 346.805 460.035 1.00 87.41  ? 76  ALA B CA  1 
ATOM 3882 C C   . ALA D 4 76  ? 333.219 345.975 458.768 1.00 87.41  ? 76  ALA B C   1 
ATOM 3883 O O   . ALA D 4 76  ? 334.003 346.245 457.863 1.00 87.41  ? 76  ALA B O   1 
ATOM 3884 C CB  . ALA D 4 76  ? 333.842 345.979 461.162 1.00 87.41  ? 76  ALA B CB  1 
ATOM 3885 N N   . GLY D 4 77  ? 332.364 344.976 458.676 1.00 86.26  ? 77  GLY B N   1 
ATOM 3886 C CA  . GLY D 4 77  ? 332.343 344.103 457.519 1.00 86.26  ? 77  GLY B CA  1 
ATOM 3887 C C   . GLY D 4 77  ? 331.938 342.702 457.914 1.00 86.26  ? 77  GLY B C   1 
ATOM 3888 O O   . GLY D 4 77  ? 332.045 342.298 459.067 1.00 86.26  ? 77  GLY B O   1 
ATOM 3889 N N   . TRP D 4 78  ? 331.465 341.951 456.923 1.00 82.77  ? 78  TRP B N   1 
ATOM 3890 C CA  . TRP D 4 78  ? 330.930 340.623 457.168 1.00 82.77  ? 78  TRP B CA  1 
ATOM 3891 C C   . TRP D 4 78  ? 331.471 339.642 456.142 1.00 82.77  ? 78  TRP B C   1 
ATOM 3892 O O   . TRP D 4 78  ? 331.952 340.032 455.078 1.00 82.77  ? 78  TRP B O   1 
ATOM 3893 C CB  . TRP D 4 78  ? 329.405 340.616 457.122 1.00 82.77  ? 78  TRP B CB  1 
ATOM 3894 C CG  . TRP D 4 78  ? 328.768 341.740 457.854 1.00 82.77  ? 78  TRP B CG  1 
ATOM 3895 C CD1 . TRP D 4 78  ? 328.309 341.725 459.130 1.00 82.77  ? 78  TRP B CD1 1 
ATOM 3896 C CD2 . TRP D 4 78  ? 328.505 343.046 457.349 1.00 82.77  ? 78  TRP B CD2 1 
ATOM 3897 N NE1 . TRP D 4 78  ? 327.779 342.943 459.458 1.00 82.77  ? 78  TRP B NE1 1 
ATOM 3898 C CE2 . TRP D 4 78  ? 327.889 343.773 458.377 1.00 82.77  ? 78  TRP B CE2 1 
ATOM 3899 C CE3 . TRP D 4 78  ? 328.735 343.673 456.128 1.00 82.77  ? 78  TRP B CE3 1 
ATOM 3900 C CZ2 . TRP D 4 78  ? 327.499 345.087 458.220 1.00 82.77  ? 78  TRP B CZ2 1 
ATOM 3901 C CZ3 . TRP D 4 78  ? 328.345 344.975 455.975 1.00 82.77  ? 78  TRP B CZ3 1 
ATOM 3902 C CH2 . TRP D 4 78  ? 327.737 345.670 457.014 1.00 82.77  ? 78  TRP B CH2 1 
ATOM 3903 N N   . TRP D 4 79  ? 331.379 338.354 456.466 1.00 87.91  ? 79  TRP B N   1 
ATOM 3904 C CA  . TRP D 4 79  ? 331.774 337.313 455.530 1.00 87.91  ? 79  TRP B CA  1 
ATOM 3905 C C   . TRP D 4 79  ? 330.892 336.089 455.706 1.00 87.91  ? 79  TRP B C   1 
ATOM 3906 O O   . TRP D 4 79  ? 330.426 335.809 456.811 1.00 87.91  ? 79  TRP B O   1 
ATOM 3907 C CB  . TRP D 4 79  ? 333.253 336.937 455.691 1.00 87.91  ? 79  TRP B CB  1 
ATOM 3908 C CG  . TRP D 4 79  ? 333.634 336.023 456.832 1.00 87.91  ? 79  TRP B CG  1 
ATOM 3909 C CD1 . TRP D 4 79  ? 333.471 334.672 456.900 1.00 87.91  ? 79  TRP B CD1 1 
ATOM 3910 C CD2 . TRP D 4 79  ? 334.330 336.392 458.019 1.00 87.91  ? 79  TRP B CD2 1 
ATOM 3911 N NE1 . TRP D 4 79  ? 333.969 334.191 458.074 1.00 87.91  ? 79  TRP B NE1 1 
ATOM 3912 C CE2 . TRP D 4 79  ? 334.512 335.228 458.777 1.00 87.91  ? 79  TRP B CE2 1 
ATOM 3913 C CE3 . TRP D 4 79  ? 334.804 337.599 458.525 1.00 87.91  ? 79  TRP B CE3 1 
ATOM 3914 C CZ2 . TRP D 4 79  ? 335.146 335.233 460.008 1.00 87.91  ? 79  TRP B CZ2 1 
ATOM 3915 C CZ3 . TRP D 4 79  ? 335.431 337.602 459.750 1.00 87.91  ? 79  TRP B CZ3 1 
ATOM 3916 C CH2 . TRP D 4 79  ? 335.595 336.428 460.478 1.00 87.91  ? 79  TRP B CH2 1 
ATOM 3917 N N   . TRP D 4 80  ? 330.709 335.339 454.625 1.00 88.03  ? 80  TRP B N   1 
ATOM 3918 C CA  . TRP D 4 80  ? 330.047 334.044 454.658 1.00 88.03  ? 80  TRP B CA  1 
ATOM 3919 C C   . TRP D 4 80  ? 330.888 333.026 453.907 1.00 88.03  ? 80  TRP B C   1 
ATOM 3920 O O   . TRP D 4 80  ? 331.360 333.301 452.802 1.00 88.03  ? 80  TRP B O   1 
ATOM 3921 C CB  . TRP D 4 80  ? 328.666 334.104 454.019 1.00 88.03  ? 80  TRP B CB  1 
ATOM 3922 C CG  . TRP D 4 80  ? 327.695 334.976 454.711 1.00 88.03  ? 80  TRP B CG  1 
ATOM 3923 C CD1 . TRP D 4 80  ? 326.898 334.637 455.753 1.00 88.03  ? 80  TRP B CD1 1 
ATOM 3924 C CD2 . TRP D 4 80  ? 327.388 336.334 454.397 1.00 88.03  ? 80  TRP B CD2 1 
ATOM 3925 N NE1 . TRP D 4 80  ? 326.118 335.699 456.118 1.00 88.03  ? 80  TRP B NE1 1 
ATOM 3926 C CE2 . TRP D 4 80  ? 326.402 336.757 455.299 1.00 88.03  ? 80  TRP B CE2 1 
ATOM 3927 C CE3 . TRP D 4 80  ? 327.858 337.235 453.444 1.00 88.03  ? 80  TRP B CE3 1 
ATOM 3928 C CZ2 . TRP D 4 80  ? 325.875 338.040 455.277 1.00 88.03  ? 80  TRP B CZ2 1 
ATOM 3929 C CZ3 . TRP D 4 80  ? 327.332 338.510 453.426 1.00 88.03  ? 80  TRP B CZ3 1 
ATOM 3930 C CH2 . TRP D 4 80  ? 326.354 338.900 454.336 1.00 88.03  ? 80  TRP B CH2 1 
ATOM 3931 N N   . LYS D 4 81  ? 331.077 331.852 454.496 1.00 92.72  ? 81  LYS B N   1 
ATOM 3932 C CA  . LYS D 4 81  ? 331.709 330.749 453.790 1.00 92.72  ? 81  LYS B CA  1 
ATOM 3933 C C   . LYS D 4 81  ? 330.648 330.058 452.953 1.00 92.72  ? 81  LYS B C   1 
ATOM 3934 O O   . LYS D 4 81  ? 329.553 329.782 453.447 1.00 92.72  ? 81  LYS B O   1 
ATOM 3935 C CB  . LYS D 4 81  ? 332.346 329.766 454.764 1.00 92.72  ? 81  LYS B CB  1 
ATOM 3936 C CG  . LYS D 4 81  ? 333.376 330.397 455.671 1.00 92.72  ? 81  LYS B CG  1 
ATOM 3937 C CD  . LYS D 4 81  ? 334.731 330.465 455.004 1.00 92.72  ? 81  LYS B CD  1 
ATOM 3938 C CE  . LYS D 4 81  ? 335.787 330.963 455.967 1.00 92.72  ? 81  LYS B CE  1 
ATOM 3939 N NZ  . LYS D 4 81  ? 337.103 331.080 455.302 1.00 92.72  ? 81  LYS B NZ  1 
ATOM 3940 N N   . LEU D 4 82  ? 330.959 329.792 451.693 1.00 96.23  ? 82  LEU B N   1 
ATOM 3941 C CA  . LEU D 4 82  ? 329.863 329.495 450.779 1.00 96.23  ? 82  LEU B CA  1 
ATOM 3942 C C   . LEU D 4 82  ? 329.314 328.068 450.823 1.00 96.23  ? 82  LEU B C   1 
ATOM 3943 O O   . LEU D 4 82  ? 328.088 327.925 450.854 1.00 96.23  ? 82  LEU B O   1 
ATOM 3944 C CB  . LEU D 4 82  ? 330.242 329.866 449.347 1.00 96.23  ? 82  LEU B CB  1 
ATOM 3945 C CG  . LEU D 4 82  ? 329.016 330.147 448.478 1.00 96.23  ? 82  LEU B CG  1 
ATOM 3946 C CD1 . LEU D 4 82  ? 327.992 331.008 449.195 1.00 96.23  ? 82  LEU B CD1 1 
ATOM 3947 C CD2 . LEU D 4 82  ? 329.446 330.831 447.214 1.00 96.23  ? 82  LEU B CD2 1 
ATOM 3948 N N   . PRO D 4 83  ? 330.114 326.972 450.823 1.00 99.02  ? 83  PRO B N   1 
ATOM 3949 C CA  . PRO D 4 83  ? 329.472 325.672 451.048 1.00 99.02  ? 83  PRO B CA  1 
ATOM 3950 C C   . PRO D 4 83  ? 329.367 325.327 452.523 1.00 99.02  ? 83  PRO B C   1 
ATOM 3951 O O   . PRO D 4 83  ? 329.599 324.183 452.920 1.00 99.02  ? 83  PRO B O   1 
ATOM 3952 C CB  . PRO D 4 83  ? 330.398 324.708 450.313 1.00 99.02  ? 83  PRO B CB  1 
ATOM 3953 C CG  . PRO D 4 83  ? 331.719 325.274 450.571 1.00 99.02  ? 83  PRO B CG  1 
ATOM 3954 C CD  . PRO D 4 83  ? 331.558 326.778 450.585 1.00 99.02  ? 83  PRO B CD  1 
ATOM 3955 N N   . ASP D 4 84  ? 329.018 326.313 453.342 1.00 106.14 ? 84  ASP B N   1 
ATOM 3956 C CA  . ASP D 4 84  ? 328.758 326.132 454.764 1.00 106.14 ? 84  ASP B CA  1 
ATOM 3957 C C   . ASP D 4 84  ? 327.485 326.812 455.237 1.00 106.14 ? 84  ASP B C   1 
ATOM 3958 O O   . ASP D 4 84  ? 326.811 326.272 456.118 1.00 106.14 ? 84  ASP B O   1 
ATOM 3959 C CB  . ASP D 4 84  ? 329.935 326.668 455.580 1.00 106.14 ? 84  ASP B CB  1 
ATOM 3960 C CG  . ASP D 4 84  ? 330.151 325.911 456.867 1.00 106.14 ? 84  ASP B CG  1 
ATOM 3961 O OD1 . ASP D 4 84  ? 329.173 325.411 457.453 1.00 106.14 ? 84  ASP B OD1 1 
ATOM 3962 O OD2 . ASP D 4 84  ? 331.315 325.817 457.302 1.00 106.14 ? 84  ASP B OD2 1 
ATOM 3963 N N   . ALA D 4 85  ? 327.110 327.956 454.672 1.00 110.66 ? 85  ALA B N   1 
ATOM 3964 C CA  . ALA D 4 85  ? 325.863 328.590 455.060 1.00 110.66 ? 85  ALA B CA  1 
ATOM 3965 C C   . ALA D 4 85  ? 324.664 327.883 454.461 1.00 110.66 ? 85  ALA B C   1 
ATOM 3966 O O   . ALA D 4 85  ? 323.543 328.086 454.932 1.00 110.66 ? 85  ALA B O   1 
ATOM 3967 C CB  . ALA D 4 85  ? 325.867 330.056 454.647 1.00 110.66 ? 85  ALA B CB  1 
ATOM 3968 N N   . LEU D 4 86  ? 324.872 327.057 453.439 1.00 114.99 ? 86  LEU B N   1 
ATOM 3969 C CA  . LEU D 4 86  ? 323.811 326.242 452.867 1.00 114.99 ? 86  LEU B CA  1 
ATOM 3970 C C   . LEU D 4 86  ? 323.787 324.838 453.454 1.00 114.99 ? 86  LEU B C   1 
ATOM 3971 O O   . LEU D 4 86  ? 323.319 323.900 452.803 1.00 114.99 ? 86  LEU B O   1 
ATOM 3972 C CB  . LEU D 4 86  ? 323.953 326.179 451.350 1.00 114.99 ? 86  LEU B CB  1 
ATOM 3973 C CG  . LEU D 4 86  ? 323.902 327.515 450.619 1.00 114.99 ? 86  LEU B CG  1 
ATOM 3974 C CD1 . LEU D 4 86  ? 323.781 327.277 449.134 1.00 114.99 ? 86  LEU B CD1 1 
ATOM 3975 C CD2 . LEU D 4 86  ? 322.743 328.346 451.113 1.00 114.99 ? 86  LEU B CD2 1 
ATOM 3976 N N   . SER D 4 87  ? 324.287 324.672 454.677 1.00 122.74 ? 87  SER B N   1 
ATOM 3977 C CA  . SER D 4 87  ? 324.308 323.354 455.291 1.00 122.74 ? 87  SER B CA  1 
ATOM 3978 C C   . SER D 4 87  ? 323.063 323.069 456.112 1.00 122.74 ? 87  SER B C   1 
ATOM 3979 O O   . SER D 4 87  ? 322.821 321.910 456.454 1.00 122.74 ? 87  SER B O   1 
ATOM 3980 C CB  . SER D 4 87  ? 325.547 323.200 456.171 1.00 122.74 ? 87  SER B CB  1 
ATOM 3981 O OG  . SER D 4 87  ? 325.314 323.701 457.471 1.00 122.74 ? 87  SER B OG  1 
ATOM 3982 N N   . GLN D 4 88  ? 322.276 324.089 456.441 1.00 124.54 ? 88  GLN B N   1 
ATOM 3983 C CA  . GLN D 4 88  ? 321.005 323.881 457.120 1.00 124.54 ? 88  GLN B CA  1 
ATOM 3984 C C   . GLN D 4 88  ? 319.824 324.234 456.236 1.00 124.54 ? 88  GLN B C   1 
ATOM 3985 O O   . GLN D 4 88  ? 318.675 324.055 456.651 1.00 124.54 ? 88  GLN B O   1 
ATOM 3986 C CB  . GLN D 4 88  ? 320.930 324.700 458.409 1.00 124.54 ? 88  GLN B CB  1 
ATOM 3987 C CG  . GLN D 4 88  ? 321.645 324.077 459.581 1.00 124.54 ? 88  GLN B CG  1 
ATOM 3988 C CD  . GLN D 4 88  ? 323.127 324.346 459.543 1.00 124.54 ? 88  GLN B CD  1 
ATOM 3989 O OE1 . GLN D 4 88  ? 323.935 323.425 459.419 1.00 124.54 ? 88  GLN B OE1 1 
ATOM 3990 N NE2 . GLN D 4 88  ? 323.499 325.616 459.639 1.00 124.54 ? 88  GLN B NE2 1 
ATOM 3991 N N   . MET D 4 89  ? 320.072 324.721 455.024 1.00 127.04 ? 89  MET B N   1 
ATOM 3992 C CA  . MET D 4 89  ? 319.009 325.256 454.181 1.00 127.04 ? 89  MET B CA  1 
ATOM 3993 C C   . MET D 4 89  ? 318.291 324.105 453.481 1.00 127.04 ? 89  MET B C   1 
ATOM 3994 O O   . MET D 4 89  ? 318.468 323.849 452.288 1.00 127.04 ? 89  MET B O   1 
ATOM 3995 C CB  . MET D 4 89  ? 319.576 326.260 453.187 1.00 127.04 ? 89  MET B CB  1 
ATOM 3996 C CG  . MET D 4 89  ? 319.939 327.599 453.798 1.00 127.04 ? 89  MET B CG  1 
ATOM 3997 S SD  . MET D 4 89  ? 318.522 328.410 454.544 1.00 127.04 ? 89  MET B SD  1 
ATOM 3998 C CE  . MET D 4 89  ? 319.309 329.819 455.308 1.00 127.04 ? 89  MET B CE  1 
ATOM 3999 N N   . GLY D 4 90  ? 317.480 323.393 454.259 1.00 138.90 ? 90  GLY B N   1 
ATOM 4000 C CA  . GLY D 4 90  ? 316.468 322.513 453.687 1.00 138.90 ? 90  GLY B CA  1 
ATOM 4001 C C   . GLY D 4 90  ? 317.035 321.260 453.048 1.00 138.90 ? 90  GLY B C   1 
ATOM 4002 O O   . GLY D 4 90  ? 317.782 320.493 453.667 1.00 138.90 ? 90  GLY B O   1 
ATOM 4003 N N   . LEU D 4 91  ? 316.663 321.053 451.781 1.00 142.90 ? 91  LEU B N   1 
ATOM 4004 C CA  . LEU D 4 91  ? 317.047 319.858 451.038 1.00 142.90 ? 91  LEU B CA  1 
ATOM 4005 C C   . LEU D 4 91  ? 318.533 319.825 450.726 1.00 142.90 ? 91  LEU B C   1 
ATOM 4006 O O   . LEU D 4 91  ? 319.099 318.740 450.549 1.00 142.90 ? 91  LEU B O   1 
ATOM 4007 C CB  . LEU D 4 91  ? 316.263 319.766 449.726 1.00 142.90 ? 91  LEU B CB  1 
ATOM 4008 C CG  . LEU D 4 91  ? 314.751 319.984 449.718 1.00 142.90 ? 91  LEU B CG  1 
ATOM 4009 C CD1 . LEU D 4 91  ? 314.395 321.416 449.330 1.00 142.90 ? 91  LEU B CD1 1 
ATOM 4010 C CD2 . LEU D 4 91  ? 314.092 318.992 448.776 1.00 142.90 ? 91  LEU B CD2 1 
ATOM 4011 N N   . PHE D 4 92  ? 319.171 320.992 450.631 1.00 140.13 ? 92  PHE B N   1 
ATOM 4012 C CA  . PHE D 4 92  ? 320.589 321.026 450.324 1.00 140.13 ? 92  PHE B CA  1 
ATOM 4013 C C   . PHE D 4 92  ? 321.430 320.498 451.471 1.00 140.13 ? 92  PHE B C   1 
ATOM 4014 O O   . PHE D 4 92  ? 322.473 319.886 451.224 1.00 140.13 ? 92  PHE B O   1 
ATOM 4015 C CB  . PHE D 4 92  ? 321.020 322.441 449.974 1.00 140.13 ? 92  PHE B CB  1 
ATOM 4016 C CG  . PHE D 4 92  ? 322.203 322.491 449.072 1.00 140.13 ? 92  PHE B CG  1 
ATOM 4017 C CD1 . PHE D 4 92  ? 322.039 322.458 447.703 1.00 140.13 ? 92  PHE B CD1 1 
ATOM 4018 C CD2 . PHE D 4 92  ? 323.480 322.544 449.590 1.00 140.13 ? 92  PHE B CD2 1 
ATOM 4019 C CE1 . PHE D 4 92  ? 323.127 322.503 446.865 1.00 140.13 ? 92  PHE B CE1 1 
ATOM 4020 C CE2 . PHE D 4 92  ? 324.576 322.581 448.757 1.00 140.13 ? 92  PHE B CE2 1 
ATOM 4021 C CZ  . PHE D 4 92  ? 324.398 322.559 447.392 1.00 140.13 ? 92  PHE B CZ  1 
ATOM 4022 N N   . GLY D 4 93  ? 320.984 320.696 452.714 1.00 141.79 ? 93  GLY B N   1 
ATOM 4023 C CA  . GLY D 4 93  ? 321.680 320.136 453.858 1.00 141.79 ? 93  GLY B CA  1 
ATOM 4024 C C   . GLY D 4 93  ? 321.621 318.629 453.949 1.00 141.79 ? 93  GLY B C   1 
ATOM 4025 O O   . GLY D 4 93  ? 322.435 318.030 454.658 1.00 141.79 ? 93  GLY B O   1 
ATOM 4026 N N   . GLN D 4 94  ? 320.674 318.004 453.252 1.00 145.12 ? 94  GLN B N   1 
ATOM 4027 C CA  . GLN D 4 94  ? 320.659 316.554 453.123 1.00 145.12 ? 94  GLN B CA  1 
ATOM 4028 C C   . GLN D 4 94  ? 321.596 316.097 452.017 1.00 145.12 ? 94  GLN B C   1 
ATOM 4029 O O   . GLN D 4 94  ? 322.367 315.153 452.209 1.00 145.12 ? 94  GLN B O   1 
ATOM 4030 C CB  . GLN D 4 94  ? 319.243 316.045 452.833 1.00 145.12 ? 94  GLN B CB  1 
ATOM 4031 C CG  . GLN D 4 94  ? 318.108 316.989 453.211 1.00 145.12 ? 94  GLN B CG  1 
ATOM 4032 C CD  . GLN D 4 94  ? 318.007 317.246 454.700 1.00 145.12 ? 94  GLN B CD  1 
ATOM 4033 O OE1 . GLN D 4 94  ? 317.999 316.314 455.502 1.00 145.12 ? 94  GLN B OE1 1 
ATOM 4034 N NE2 . GLN D 4 94  ? 317.934 318.517 455.077 1.00 145.12 ? 94  GLN B NE2 1 
ATOM 4035 N N   . ASN D 4 95  ? 321.562 316.775 450.868 1.00 147.47 ? 95  ASN B N   1 
ATOM 4036 C CA  . ASN D 4 95  ? 322.401 316.403 449.739 1.00 147.47 ? 95  ASN B CA  1 
ATOM 4037 C C   . ASN D 4 95  ? 323.873 316.701 449.969 1.00 147.47 ? 95  ASN B C   1 
ATOM 4038 O O   . ASN D 4 95  ? 324.718 316.113 449.288 1.00 147.47 ? 95  ASN B O   1 
ATOM 4039 C CB  . ASN D 4 95  ? 321.919 317.107 448.471 1.00 147.47 ? 95  ASN B CB  1 
ATOM 4040 C CG  . ASN D 4 95  ? 320.679 316.458 447.888 1.00 147.47 ? 95  ASN B CG  1 
ATOM 4041 O OD1 . ASN D 4 95  ? 319.895 315.842 448.607 1.00 147.47 ? 95  ASN B OD1 1 
ATOM 4042 N ND2 . ASN D 4 95  ? 320.497 316.589 446.579 1.00 147.47 ? 95  ASN B ND2 1 
ATOM 4043 N N   . MET D 4 96  ? 324.204 317.587 450.904 1.00 144.57 ? 96  MET B N   1 
ATOM 4044 C CA  . MET D 4 96  ? 325.588 317.689 451.342 1.00 144.57 ? 96  MET B CA  1 
ATOM 4045 C C   . MET D 4 96  ? 325.960 316.563 452.297 1.00 144.57 ? 96  MET B C   1 
ATOM 4046 O O   . MET D 4 96  ? 327.069 316.030 452.214 1.00 144.57 ? 96  MET B O   1 
ATOM 4047 C CB  . MET D 4 96  ? 325.842 319.037 452.015 1.00 144.57 ? 96  MET B CB  1 
ATOM 4048 C CG  . MET D 4 96  ? 326.134 320.175 451.062 1.00 144.57 ? 96  MET B CG  1 
ATOM 4049 S SD  . MET D 4 96  ? 326.104 321.759 451.920 1.00 144.57 ? 96  MET B SD  1 
ATOM 4050 C CE  . MET D 4 96  ? 327.156 321.397 453.321 1.00 144.57 ? 96  MET B CE  1 
ATOM 4051 N N   . GLN D 4 97  ? 325.055 316.185 453.198 1.00 145.68 ? 97  GLN B N   1 
ATOM 4052 C CA  . GLN D 4 97  ? 325.361 315.171 454.199 1.00 145.68 ? 97  GLN B CA  1 
ATOM 4053 C C   . GLN D 4 97  ? 325.281 313.753 453.660 1.00 145.68 ? 97  GLN B C   1 
ATOM 4054 O O   . GLN D 4 97  ? 326.084 312.904 454.059 1.00 145.68 ? 97  GLN B O   1 
ATOM 4055 C CB  . GLN D 4 97  ? 324.420 315.305 455.397 1.00 145.68 ? 97  GLN B CB  1 
ATOM 4056 C CG  . GLN D 4 97  ? 324.999 314.756 456.689 1.00 145.68 ? 97  GLN B CG  1 
ATOM 4057 C CD  . GLN D 4 97  ? 324.089 314.979 457.877 1.00 145.68 ? 97  GLN B CD  1 
ATOM 4058 O OE1 . GLN D 4 97  ? 323.034 314.355 457.993 1.00 145.68 ? 97  GLN B OE1 1 
ATOM 4059 N NE2 . GLN D 4 97  ? 324.492 315.874 458.770 1.00 145.68 ? 97  GLN B NE2 1 
ATOM 4060 N N   . TYR D 4 98  ? 324.328 313.470 452.774 1.00 147.59 ? 98  TYR B N   1 
ATOM 4061 C CA  . TYR D 4 98  ? 324.189 312.113 452.262 1.00 147.59 ? 98  TYR B CA  1 
ATOM 4062 C C   . TYR D 4 98  ? 325.242 311.935 451.181 1.00 147.59 ? 98  TYR B C   1 
ATOM 4063 O O   . TYR D 4 98  ? 325.713 310.818 450.950 1.00 147.59 ? 98  TYR B O   1 
ATOM 4064 C CB  . TYR D 4 98  ? 322.803 311.915 451.655 1.00 147.59 ? 98  TYR B CB  1 
ATOM 4065 C CG  . TYR D 4 98  ? 321.719 311.587 452.654 1.00 147.59 ? 98  TYR B CG  1 
ATOM 4066 C CD1 . TYR D 4 98  ? 321.312 312.518 453.601 1.00 147.59 ? 98  TYR B CD1 1 
ATOM 4067 C CD2 . TYR D 4 98  ? 321.095 310.349 452.641 1.00 147.59 ? 98  TYR B CD2 1 
ATOM 4068 C CE1 . TYR D 4 98  ? 320.318 312.225 454.509 1.00 147.59 ? 98  TYR B CE1 1 
ATOM 4069 C CE2 . TYR D 4 98  ? 320.098 310.045 453.546 1.00 147.59 ? 98  TYR B CE2 1 
ATOM 4070 C CZ  . TYR D 4 98  ? 319.715 310.986 454.477 1.00 147.59 ? 98  TYR B CZ  1 
ATOM 4071 O OH  . TYR D 4 98  ? 318.723 310.687 455.380 1.00 147.59 ? 98  TYR B OH  1 
ATOM 4072 N N   . HIS D 4 99  ? 325.528 313.007 450.451 1.00 144.95 ? 99  HIS B N   1 
ATOM 4073 C CA  . HIS D 4 99  ? 326.608 312.974 449.476 1.00 144.95 ? 99  HIS B CA  1 
ATOM 4074 C C   . HIS D 4 99  ? 327.817 313.816 449.853 1.00 144.95 ? 99  HIS B C   1 
ATOM 4075 O O   . HIS D 4 99  ? 327.790 315.040 449.736 1.00 144.95 ? 99  HIS B O   1 
ATOM 4076 C CB  . HIS D 4 99  ? 326.080 313.516 448.144 1.00 144.95 ? 99  HIS B CB  1 
ATOM 4077 C CG  . HIS D 4 99  ? 324.892 312.780 447.606 1.00 144.95 ? 99  HIS B CG  1 
ATOM 4078 N ND1 . HIS D 4 99  ? 324.962 311.488 447.131 1.00 144.95 ? 99  HIS B ND1 1 
ATOM 4079 C CD2 . HIS D 4 99  ? 323.603 313.166 447.452 1.00 144.95 ? 99  HIS B CD2 1 
ATOM 4080 C CE1 . HIS D 4 99  ? 323.766 311.106 446.719 1.00 144.95 ? 99  HIS B CE1 1 
ATOM 4081 N NE2 . HIS D 4 99  ? 322.924 312.106 446.902 1.00 144.95 ? 99  HIS B NE2 1 
ATOM 4082 N N   . TYR D 4 100 ? 328.862 313.161 450.347 1.00 147.29 ? 100 TYR B N   1 
ATOM 4083 C CA  . TYR D 4 100 ? 330.051 313.876 450.792 1.00 147.29 ? 100 TYR B CA  1 
ATOM 4084 C C   . TYR D 4 100 ? 330.745 314.645 449.675 1.00 147.29 ? 100 TYR B C   1 
ATOM 4085 O O   . TYR D 4 100 ? 331.008 315.841 449.798 1.00 147.29 ? 100 TYR B O   1 
ATOM 4086 C CB  . TYR D 4 100 ? 331.060 313.057 451.597 1.00 147.29 ? 100 TYR B CB  1 
ATOM 4087 C CG  . TYR D 4 100 ? 330.668 312.925 453.051 1.00 147.29 ? 100 TYR B CG  1 
ATOM 4088 C CD1 . TYR D 4 100 ? 330.207 311.721 453.561 1.00 147.29 ? 100 TYR B CD1 1 
ATOM 4089 C CD2 . TYR D 4 100 ? 330.739 314.015 453.907 1.00 147.29 ? 100 TYR B CD2 1 
ATOM 4090 C CE1 . TYR D 4 100 ? 329.839 311.603 454.887 1.00 147.29 ? 100 TYR B CE1 1 
ATOM 4091 C CE2 . TYR D 4 100 ? 330.375 313.907 455.234 1.00 147.29 ? 100 TYR B CE2 1 
ATOM 4092 C CZ  . TYR D 4 100 ? 329.925 312.700 455.720 1.00 147.29 ? 100 TYR B CZ  1 
ATOM 4093 O OH  . TYR D 4 100 ? 329.561 312.594 457.044 1.00 147.29 ? 100 TYR B OH  1 
ATOM 4094 N N   . LEU D 4 101 ? 331.026 313.951 448.581 1.00 140.42 ? 101 LEU B N   1 
ATOM 4095 C CA  . LEU D 4 101 ? 331.665 314.580 447.435 1.00 140.42 ? 101 LEU B CA  1 
ATOM 4096 C C   . LEU D 4 101 ? 330.630 315.408 446.696 1.00 140.42 ? 101 LEU B C   1 
ATOM 4097 O O   . LEU D 4 101 ? 329.436 315.139 446.800 1.00 140.42 ? 101 LEU B O   1 
ATOM 4098 C CB  . LEU D 4 101 ? 332.305 313.532 446.529 1.00 140.42 ? 101 LEU B CB  1 
ATOM 4099 C CG  . LEU D 4 101 ? 333.724 313.124 446.930 1.00 140.42 ? 101 LEU B CG  1 
ATOM 4100 C CD1 . LEU D 4 101 ? 333.728 312.403 448.267 1.00 140.42 ? 101 LEU B CD1 1 
ATOM 4101 C CD2 . LEU D 4 101 ? 334.354 312.254 445.856 1.00 140.42 ? 101 LEU B CD2 1 
ATOM 4102 N N   . GLY D 4 102 ? 331.074 316.425 445.972 1.00 139.08 ? 102 GLY B N   1 
ATOM 4103 C CA  . GLY D 4 102 ? 330.146 317.263 445.242 1.00 139.08 ? 102 GLY B CA  1 
ATOM 4104 C C   . GLY D 4 102 ? 330.909 318.386 444.582 1.00 139.08 ? 102 GLY B C   1 
ATOM 4105 O O   . GLY D 4 102 ? 332.072 318.655 444.886 1.00 139.08 ? 102 GLY B O   1 
ATOM 4106 N N   . ARG D 4 103 ? 330.228 319.051 443.647 1.00 132.32 ? 103 ARG B N   1 
ATOM 4107 C CA  . ARG D 4 103 ? 330.780 320.190 442.925 1.00 132.32 ? 103 ARG B CA  1 
ATOM 4108 C C   . ARG D 4 103 ? 329.631 321.035 442.401 1.00 132.32 ? 103 ARG B C   1 
ATOM 4109 O O   . ARG D 4 103 ? 328.715 320.512 441.763 1.00 132.32 ? 103 ARG B O   1 
ATOM 4110 C CB  . ARG D 4 103 ? 331.670 319.737 441.769 1.00 132.32 ? 103 ARG B CB  1 
ATOM 4111 C CG  . ARG D 4 103 ? 331.169 318.504 441.059 1.00 132.32 ? 103 ARG B CG  1 
ATOM 4112 C CD  . ARG D 4 103 ? 331.722 318.430 439.665 1.00 132.32 ? 103 ARG B CD  1 
ATOM 4113 N NE  . ARG D 4 103 ? 331.364 319.605 438.882 1.00 132.32 ? 103 ARG B NE  1 
ATOM 4114 C CZ  . ARG D 4 103 ? 332.001 319.975 437.778 1.00 132.32 ? 103 ARG B CZ  1 
ATOM 4115 N NH1 . ARG D 4 103 ? 333.021 319.257 437.335 1.00 132.32 ? 103 ARG B NH1 1 
ATOM 4116 N NH2 . ARG D 4 103 ? 331.617 321.056 437.117 1.00 132.32 ? 103 ARG B NH2 1 
ATOM 4117 N N   . THR D 4 104 ? 329.667 322.332 442.694 1.00 128.38 ? 104 THR B N   1 
ATOM 4118 C CA  . THR D 4 104 ? 328.581 323.251 442.377 1.00 128.38 ? 104 THR B CA  1 
ATOM 4119 C C   . THR D 4 104 ? 329.137 324.553 441.807 1.00 128.38 ? 104 THR B C   1 
ATOM 4120 O O   . THR D 4 104 ? 330.328 324.847 441.913 1.00 128.38 ? 104 THR B O   1 
ATOM 4121 C CB  . THR D 4 104 ? 327.721 323.574 443.617 1.00 128.38 ? 104 THR B CB  1 
ATOM 4122 O OG1 . THR D 4 104 ? 328.528 324.229 444.601 1.00 128.38 ? 104 THR B OG1 1 
ATOM 4123 C CG2 . THR D 4 104 ? 327.050 322.341 444.226 1.00 128.38 ? 104 THR B CG2 1 
ATOM 4124 N N   . GLY D 4 105 ? 328.245 325.334 441.189 1.00 117.17 ? 105 GLY B N   1 
ATOM 4125 C CA  . GLY D 4 105 ? 328.508 326.719 440.865 1.00 117.17 ? 105 GLY B CA  1 
ATOM 4126 C C   . GLY D 4 105 ? 327.463 327.600 441.535 1.00 117.17 ? 105 GLY B C   1 
ATOM 4127 O O   . GLY D 4 105 ? 326.420 327.124 441.989 1.00 117.17 ? 105 GLY B O   1 
ATOM 4128 N N   . TYR D 4 106 ? 327.751 328.894 441.601 1.00 102.67 ? 106 TYR B N   1 
ATOM 4129 C CA  . TYR D 4 106 ? 326.928 329.779 442.405 1.00 102.67 ? 106 TYR B CA  1 
ATOM 4130 C C   . TYR D 4 106 ? 326.517 331.019 441.633 1.00 102.67 ? 106 TYR B C   1 
ATOM 4131 O O   . TYR D 4 106 ? 327.002 331.294 440.535 1.00 102.67 ? 106 TYR B O   1 
ATOM 4132 C CB  . TYR D 4 106 ? 327.646 330.184 443.676 1.00 102.67 ? 106 TYR B CB  1 
ATOM 4133 C CG  . TYR D 4 106 ? 327.889 329.015 444.572 1.00 102.67 ? 106 TYR B CG  1 
ATOM 4134 C CD1 . TYR D 4 106 ? 326.910 328.578 445.438 1.00 102.67 ? 106 TYR B CD1 1 
ATOM 4135 C CD2 . TYR D 4 106 ? 329.092 328.335 444.540 1.00 102.67 ? 106 TYR B CD2 1 
ATOM 4136 C CE1 . TYR D 4 106 ? 327.123 327.505 446.258 1.00 102.67 ? 106 TYR B CE1 1 
ATOM 4137 C CE2 . TYR D 4 106 ? 329.318 327.263 445.354 1.00 102.67 ? 106 TYR B CE2 1 
ATOM 4138 C CZ  . TYR D 4 106 ? 328.329 326.854 446.213 1.00 102.67 ? 106 TYR B CZ  1 
ATOM 4139 O OH  . TYR D 4 106 ? 328.550 325.774 447.030 1.00 102.67 ? 106 TYR B OH  1 
ATOM 4140 N N   . THR D 4 107 ? 325.593 331.757 442.237 1.00 97.18  ? 107 THR B N   1 
ATOM 4141 C CA  . THR D 4 107 ? 325.070 332.996 441.674 1.00 97.18  ? 107 THR B CA  1 
ATOM 4142 C C   . THR D 4 107 ? 324.564 333.816 442.846 1.00 97.18  ? 107 THR B C   1 
ATOM 4143 O O   . THR D 4 107 ? 323.644 333.385 443.544 1.00 97.18  ? 107 THR B O   1 
ATOM 4144 C CB  . THR D 4 107 ? 323.951 332.730 440.682 1.00 97.18  ? 107 THR B CB  1 
ATOM 4145 O OG1 . THR D 4 107 ? 324.474 332.045 439.542 1.00 97.18  ? 107 THR B OG1 1 
ATOM 4146 C CG2 . THR D 4 107 ? 323.334 334.032 440.241 1.00 97.18  ? 107 THR B CG2 1 
ATOM 4147 N N   . ILE D 4 108 ? 325.163 334.979 443.072 1.00 86.73  ? 108 ILE B N   1 
ATOM 4148 C CA  . ILE D 4 108 ? 324.926 335.771 444.269 1.00 86.73  ? 108 ILE B CA  1 
ATOM 4149 C C   . ILE D 4 108 ? 324.228 337.063 443.876 1.00 86.73  ? 108 ILE B C   1 
ATOM 4150 O O   . ILE D 4 108 ? 324.560 337.665 442.852 1.00 86.73  ? 108 ILE B O   1 
ATOM 4151 C CB  . ILE D 4 108 ? 326.244 336.055 444.998 1.00 86.73  ? 108 ILE B CB  1 
ATOM 4152 C CG1 . ILE D 4 108 ? 327.089 334.791 445.028 1.00 86.73  ? 108 ILE B CG1 1 
ATOM 4153 C CG2 . ILE D 4 108 ? 325.985 336.515 446.396 1.00 86.73  ? 108 ILE B CG2 1 
ATOM 4154 C CD1 . ILE D 4 108 ? 328.488 335.011 445.489 1.00 86.73  ? 108 ILE B CD1 1 
ATOM 4155 N N   . HIS D 4 109 ? 323.257 337.481 444.679 1.00 84.52  ? 109 HIS B N   1 
ATOM 4156 C CA  . HIS D 4 109 ? 322.569 338.750 444.494 1.00 84.52  ? 109 HIS B CA  1 
ATOM 4157 C C   . HIS D 4 109 ? 322.656 339.531 445.790 1.00 84.52  ? 109 HIS B C   1 
ATOM 4158 O O   . HIS D 4 109 ? 322.125 339.090 446.813 1.00 84.52  ? 109 HIS B O   1 
ATOM 4159 C CB  . HIS D 4 109 ? 321.108 338.541 444.118 1.00 84.52  ? 109 HIS B CB  1 
ATOM 4160 C CG  . HIS D 4 109 ? 320.906 338.047 442.726 1.00 84.52  ? 109 HIS B CG  1 
ATOM 4161 N ND1 . HIS D 4 109 ? 321.399 336.840 442.287 1.00 84.52  ? 109 HIS B ND1 1 
ATOM 4162 C CD2 . HIS D 4 109 ? 320.251 338.592 441.676 1.00 84.52  ? 109 HIS B CD2 1 
ATOM 4163 C CE1 . HIS D 4 109 ? 321.060 336.663 441.023 1.00 84.52  ? 109 HIS B CE1 1 
ATOM 4164 N NE2 . HIS D 4 109 ? 320.364 337.713 440.628 1.00 84.52  ? 109 HIS B NE2 1 
ATOM 4165 N N   . VAL D 4 110 ? 323.311 340.682 445.753 1.00 81.19  ? 110 VAL B N   1 
ATOM 4166 C CA  . VAL D 4 110 ? 323.419 341.554 446.912 1.00 81.19  ? 110 VAL B CA  1 
ATOM 4167 C C   . VAL D 4 110 ? 322.819 342.898 446.551 1.00 81.19  ? 110 VAL B C   1 
ATOM 4168 O O   . VAL D 4 110 ? 323.236 343.523 445.570 1.00 81.19  ? 110 VAL B O   1 
ATOM 4169 C CB  . VAL D 4 110 ? 324.876 341.715 447.366 1.00 81.19  ? 110 VAL B CB  1 
ATOM 4170 C CG1 . VAL D 4 110 ? 324.979 342.783 448.420 1.00 81.19  ? 110 VAL B CG1 1 
ATOM 4171 C CG2 . VAL D 4 110 ? 325.385 340.411 447.901 1.00 81.19  ? 110 VAL B CG2 1 
ATOM 4172 N N   . GLN D 4 111 ? 321.841 343.338 447.335 1.00 86.79  ? 111 GLN B N   1 
ATOM 4173 C CA  . GLN D 4 111 ? 321.213 344.631 447.107 1.00 86.79  ? 111 GLN B CA  1 
ATOM 4174 C C   . GLN D 4 111 ? 320.846 345.246 448.445 1.00 86.79  ? 111 GLN B C   1 
ATOM 4175 O O   . GLN D 4 111 ? 320.215 344.599 449.282 1.00 86.79  ? 111 GLN B O   1 
ATOM 4176 C CB  . GLN D 4 111 ? 319.996 344.494 446.192 1.00 86.79  ? 111 GLN B CB  1 
ATOM 4177 C CG  . GLN D 4 111 ? 318.976 343.452 446.592 1.00 86.79  ? 111 GLN B CG  1 
ATOM 4178 C CD  . GLN D 4 111 ? 317.898 343.291 445.556 1.00 86.79  ? 111 GLN B CD  1 
ATOM 4179 O OE1 . GLN D 4 111 ? 317.859 344.025 444.572 1.00 86.79  ? 111 GLN B OE1 1 
ATOM 4180 N NE2 . GLN D 4 111 ? 317.025 342.314 445.756 1.00 86.79  ? 111 GLN B NE2 1 
ATOM 4181 N N   . CYS D 4 112 ? 321.295 346.471 448.669 1.00 93.37  ? 112 CYS B N   1 
ATOM 4182 C CA  . CYS D 4 112 ? 320.964 347.213 449.872 1.00 93.37  ? 112 CYS B CA  1 
ATOM 4183 C C   . CYS D 4 112 ? 320.077 348.390 449.510 1.00 93.37  ? 112 CYS B C   1 
ATOM 4184 O O   . CYS D 4 112 ? 320.373 349.138 448.580 1.00 93.37  ? 112 CYS B O   1 
ATOM 4185 C CB  . CYS D 4 112 ? 322.227 347.679 450.595 1.00 93.37  ? 112 CYS B CB  1 
ATOM 4186 S SG  . CYS D 4 112 ? 323.369 348.665 449.623 1.00 93.37  ? 112 CYS B SG  1 
ATOM 4187 N N   . ASN D 4 113 ? 318.988 348.549 450.242 1.00 88.71  ? 113 ASN B N   1 
ATOM 4188 C CA  . ASN D 4 113 ? 317.944 349.499 449.890 1.00 88.71  ? 113 ASN B CA  1 
ATOM 4189 C C   . ASN D 4 113 ? 317.932 350.664 450.871 1.00 88.71  ? 113 ASN B C   1 
ATOM 4190 O O   . ASN D 4 113 ? 317.746 350.478 452.075 1.00 88.71  ? 113 ASN B O   1 
ATOM 4191 C CB  . ASN D 4 113 ? 316.596 348.791 449.823 1.00 88.71  ? 113 ASN B CB  1 
ATOM 4192 C CG  . ASN D 4 113 ? 316.380 347.842 450.975 1.00 88.71  ? 113 ASN B CG  1 
ATOM 4193 O OD1 . ASN D 4 113 ? 317.228 347.706 451.852 1.00 88.71  ? 113 ASN B OD1 1 
ATOM 4194 N ND2 . ASN D 4 113 ? 315.240 347.169 450.974 1.00 88.71  ? 113 ASN B ND2 1 
ATOM 4195 N N   . ALA D 4 114 ? 318.142 351.865 450.349 1.00 90.34  ? 114 ALA B N   1 
ATOM 4196 C CA  . ALA D 4 114 ? 318.072 353.083 451.133 1.00 90.34  ? 114 ALA B CA  1 
ATOM 4197 C C   . ALA D 4 114 ? 317.493 354.209 450.291 1.00 90.34  ? 114 ALA B C   1 
ATOM 4198 O O   . ALA D 4 114 ? 317.193 354.039 449.109 1.00 90.34  ? 114 ALA B O   1 
ATOM 4199 C CB  . ALA D 4 114 ? 319.449 353.483 451.662 1.00 90.34  ? 114 ALA B CB  1 
ATOM 4200 N N   . SER D 4 115 ? 317.352 355.369 450.919 1.00 93.16  ? 115 SER B N   1 
ATOM 4201 C CA  . SER D 4 115 ? 316.761 356.531 450.275 1.00 93.16  ? 115 SER B CA  1 
ATOM 4202 C C   . SER D 4 115 ? 317.822 357.277 449.471 1.00 93.16  ? 115 SER B C   1 
ATOM 4203 O O   . SER D 4 115 ? 318.931 356.789 449.243 1.00 93.16  ? 115 SER B O   1 
ATOM 4204 C CB  . SER D 4 115 ? 316.127 357.440 451.317 1.00 93.16  ? 115 SER B CB  1 
ATOM 4205 O OG  . SER D 4 115 ? 317.090 358.346 451.821 1.00 93.16  ? 115 SER B OG  1 
ATOM 4206 N N   . LYS D 4 116 ? 317.489 358.483 449.029 1.00 95.55  ? 116 LYS B N   1 
ATOM 4207 C CA  . LYS D 4 116 ? 318.461 359.352 448.391 1.00 95.55  ? 116 LYS B CA  1 
ATOM 4208 C C   . LYS D 4 116 ? 319.227 360.206 449.385 1.00 95.55  ? 116 LYS B C   1 
ATOM 4209 O O   . LYS D 4 116 ? 320.032 361.040 448.966 1.00 95.55  ? 116 LYS B O   1 
ATOM 4210 C CB  . LYS D 4 116 ? 317.777 360.261 447.373 1.00 95.55  ? 116 LYS B CB  1 
ATOM 4211 C CG  . LYS D 4 116 ? 317.535 359.608 446.034 1.00 95.55  ? 116 LYS B CG  1 
ATOM 4212 C CD  . LYS D 4 116 ? 317.024 360.618 445.022 1.00 95.55  ? 116 LYS B CD  1 
ATOM 4213 C CE  . LYS D 4 116 ? 316.712 359.959 443.695 1.00 95.55  ? 116 LYS B CE  1 
ATOM 4214 N NZ  . LYS D 4 116 ? 317.853 359.138 443.218 1.00 95.55  ? 116 LYS B NZ  1 
ATOM 4215 N N   . PHE D 4 117 ? 319.001 360.027 450.683 1.00 90.71  ? 117 PHE B N   1 
ATOM 4216 C CA  . PHE D 4 117 ? 319.687 360.811 451.695 1.00 90.71  ? 117 PHE B CA  1 
ATOM 4217 C C   . PHE D 4 117 ? 320.716 360.012 452.471 1.00 90.71  ? 117 PHE B C   1 
ATOM 4218 O O   . PHE D 4 117 ? 321.223 360.504 453.482 1.00 90.71  ? 117 PHE B O   1 
ATOM 4219 C CB  . PHE D 4 117 ? 318.682 361.426 452.667 1.00 90.71  ? 117 PHE B CB  1 
ATOM 4220 C CG  . PHE D 4 117 ? 317.613 362.217 451.997 1.00 90.71  ? 117 PHE B CG  1 
ATOM 4221 C CD1 . PHE D 4 117 ? 317.929 363.361 451.295 1.00 90.71  ? 117 PHE B CD1 1 
ATOM 4222 C CD2 . PHE D 4 117 ? 316.297 361.807 452.045 1.00 90.71  ? 117 PHE B CD2 1 
ATOM 4223 C CE1 . PHE D 4 117 ? 316.950 364.095 450.669 1.00 90.71  ? 117 PHE B CE1 1 
ATOM 4224 C CE2 . PHE D 4 117 ? 315.312 362.538 451.422 1.00 90.71  ? 117 PHE B CE2 1 
ATOM 4225 C CZ  . PHE D 4 117 ? 315.641 363.683 450.732 1.00 90.71  ? 117 PHE B CZ  1 
ATOM 4226 N N   . HIS D 4 118 ? 321.025 358.798 452.044 1.00 86.82  ? 118 HIS B N   1 
ATOM 4227 C CA  . HIS D 4 118 ? 322.115 358.037 452.627 1.00 86.82  ? 118 HIS B CA  1 
ATOM 4228 C C   . HIS D 4 118 ? 323.332 358.102 451.718 1.00 86.82  ? 118 HIS B C   1 
ATOM 4229 O O   . HIS D 4 118 ? 323.258 358.530 450.567 1.00 86.82  ? 118 HIS B O   1 
ATOM 4230 C CB  . HIS D 4 118 ? 321.705 356.586 452.859 1.00 86.82  ? 118 HIS B CB  1 
ATOM 4231 C CG  . HIS D 4 118 ? 320.559 356.429 453.801 1.00 86.82  ? 118 HIS B CG  1 
ATOM 4232 N ND1 . HIS D 4 118 ? 319.254 356.635 453.419 1.00 86.82  ? 118 HIS B ND1 1 
ATOM 4233 C CD2 . HIS D 4 118 ? 320.522 356.089 455.109 1.00 86.82  ? 118 HIS B CD2 1 
ATOM 4234 C CE1 . HIS D 4 118 ? 318.460 356.422 454.451 1.00 86.82  ? 118 HIS B CE1 1 
ATOM 4235 N NE2 . HIS D 4 118 ? 319.204 356.093 455.490 1.00 86.82  ? 118 HIS B NE2 1 
ATOM 4236 N N   . GLN D 4 119 ? 324.465 357.666 452.252 1.00 87.91  ? 119 GLN B N   1 
ATOM 4237 C CA  . GLN D 4 119 ? 325.707 357.705 451.506 1.00 87.91  ? 119 GLN B CA  1 
ATOM 4238 C C   . GLN D 4 119 ? 326.643 356.645 452.052 1.00 87.91  ? 119 GLN B C   1 
ATOM 4239 O O   . GLN D 4 119 ? 326.672 356.385 453.256 1.00 87.91  ? 119 GLN B O   1 
ATOM 4240 C CB  . GLN D 4 119 ? 326.358 359.083 451.588 1.00 87.91  ? 119 GLN B CB  1 
ATOM 4241 C CG  . GLN D 4 119 ? 326.412 359.639 452.985 1.00 87.91  ? 119 GLN B CG  1 
ATOM 4242 C CD  . GLN D 4 119 ? 326.885 361.067 453.020 1.00 87.91  ? 119 GLN B CD  1 
ATOM 4243 O OE1 . GLN D 4 119 ? 327.903 361.375 453.629 1.00 87.91  ? 119 GLN B OE1 1 
ATOM 4244 N NE2 . GLN D 4 119 ? 326.146 361.952 452.366 1.00 87.91  ? 119 GLN B NE2 1 
ATOM 4245 N N   . GLY D 4 120 ? 327.404 356.037 451.161 1.00 83.38  ? 120 GLY B N   1 
ATOM 4246 C CA  . GLY D 4 120 ? 328.338 355.004 451.556 1.00 83.38  ? 120 GLY B CA  1 
ATOM 4247 C C   . GLY D 4 120 ? 328.735 354.174 450.359 1.00 83.38  ? 120 GLY B C   1 
ATOM 4248 O O   . GLY D 4 120 ? 328.127 354.244 449.294 1.00 83.38  ? 120 GLY B O   1 
ATOM 4249 N N   . CYS D 4 121 ? 329.786 353.387 450.554 1.00 81.40  ? 121 CYS B N   1 
ATOM 4250 C CA  . CYS D 4 121 ? 330.281 352.549 449.475 1.00 81.40  ? 121 CYS B CA  1 
ATOM 4251 C C   . CYS D 4 121 ? 330.593 351.174 450.025 1.00 81.40  ? 121 CYS B C   1 
ATOM 4252 O O   . CYS D 4 121 ? 331.271 351.052 451.046 1.00 81.40  ? 121 CYS B O   1 
ATOM 4253 C CB  . CYS D 4 121 ? 331.529 353.141 448.839 1.00 81.40  ? 121 CYS B CB  1 
ATOM 4254 S SG  . CYS D 4 121 ? 332.177 352.160 447.493 1.00 81.40  ? 121 CYS B SG  1 
ATOM 4255 N N   . LEU D 4 122 ? 330.104 350.150 449.350 1.00 78.68  ? 122 LEU B N   1 
ATOM 4256 C CA  . LEU D 4 122 ? 330.410 348.781 449.707 1.00 78.68  ? 122 LEU B CA  1 
ATOM 4257 C C   . LEU D 4 122 ? 331.342 348.180 448.674 1.00 78.68  ? 122 LEU B C   1 
ATOM 4258 O O   . LEU D 4 122 ? 331.410 348.617 447.525 1.00 78.68  ? 122 LEU B O   1 
ATOM 4259 C CB  . LEU D 4 122 ? 329.137 347.947 449.805 1.00 78.68  ? 122 LEU B CB  1 
ATOM 4260 C CG  . LEU D 4 122 ? 328.147 348.435 450.840 1.00 78.68  ? 122 LEU B CG  1 
ATOM 4261 C CD1 . LEU D 4 122 ? 326.955 347.518 450.847 1.00 78.68  ? 122 LEU B CD1 1 
ATOM 4262 C CD2 . LEU D 4 122 ? 328.820 348.454 452.183 1.00 78.68  ? 122 LEU B CD2 1 
ATOM 4263 N N   . LEU D 4 123 ? 332.058 347.154 449.102 1.00 76.49  ? 123 LEU B N   1 
ATOM 4264 C CA  . LEU D 4 123 ? 332.876 346.352 448.212 1.00 76.49  ? 123 LEU B CA  1 
ATOM 4265 C C   . LEU D 4 123 ? 332.438 344.914 448.382 1.00 76.49  ? 123 LEU B C   1 
ATOM 4266 O O   . LEU D 4 123 ? 332.643 344.329 449.446 1.00 76.49  ? 123 LEU B O   1 
ATOM 4267 C CB  . LEU D 4 123 ? 334.354 346.503 448.538 1.00 76.49  ? 123 LEU B CB  1 
ATOM 4268 C CG  . LEU D 4 123 ? 335.234 345.522 447.785 1.00 76.49  ? 123 LEU B CG  1 
ATOM 4269 C CD1 . LEU D 4 123 ? 335.572 346.085 446.436 1.00 76.49  ? 123 LEU B CD1 1 
ATOM 4270 C CD2 . LEU D 4 123 ? 336.478 345.231 448.576 1.00 76.49  ? 123 LEU B CD2 1 
ATOM 4271 N N   . VAL D 4 124 ? 331.805 344.360 447.362 1.00 77.76  ? 124 VAL B N   1 
ATOM 4272 C CA  . VAL D 4 124 ? 331.368 342.974 447.380 1.00 77.76  ? 124 VAL B CA  1 
ATOM 4273 C C   . VAL D 4 124 ? 332.383 342.187 446.581 1.00 77.76  ? 124 VAL B C   1 
ATOM 4274 O O   . VAL D 4 124 ? 332.572 342.448 445.390 1.00 77.76  ? 124 VAL B O   1 
ATOM 4275 C CB  . VAL D 4 124 ? 329.965 342.811 446.798 1.00 77.76  ? 124 VAL B CB  1 
ATOM 4276 C CG1 . VAL D 4 124 ? 329.676 341.356 446.562 1.00 77.76  ? 124 VAL B CG1 1 
ATOM 4277 C CG2 . VAL D 4 124 ? 328.960 343.393 447.740 1.00 77.76  ? 124 VAL B CG2 1 
ATOM 4278 N N   . VAL D 4 125 ? 333.050 341.238 447.224 1.00 76.65  ? 125 VAL B N   1 
ATOM 4279 C CA  . VAL D 4 125 ? 334.083 340.456 446.569 1.00 76.65  ? 125 VAL B CA  1 
ATOM 4280 C C   . VAL D 4 125 ? 333.919 339.008 447.011 1.00 76.65  ? 125 VAL B C   1 
ATOM 4281 O O   . VAL D 4 125 ? 333.423 338.721 448.101 1.00 76.65  ? 125 VAL B O   1 
ATOM 4282 C CB  . VAL D 4 125 ? 335.489 341.012 446.880 1.00 76.65  ? 125 VAL B CB  1 
ATOM 4283 C CG1 . VAL D 4 125 ? 335.874 340.790 448.323 1.00 76.65  ? 125 VAL B CG1 1 
ATOM 4284 C CG2 . VAL D 4 125 ? 336.533 340.476 445.926 1.00 76.65  ? 125 VAL B CG2 1 
ATOM 4285 N N   . CYS D 4 126 ? 334.284 338.087 446.124 1.00 87.32  ? 126 CYS B N   1 
ATOM 4286 C CA  . CYS D 4 126 ? 334.092 336.659 446.357 1.00 87.32  ? 126 CYS B CA  1 
ATOM 4287 C C   . CYS D 4 126 ? 335.435 335.970 446.155 1.00 87.32  ? 126 CYS B C   1 
ATOM 4288 O O   . CYS D 4 126 ? 335.796 335.607 445.035 1.00 87.32  ? 126 CYS B O   1 
ATOM 4289 C CB  . CYS D 4 126 ? 333.024 336.098 445.432 1.00 87.32  ? 126 CYS B CB  1 
ATOM 4290 S SG  . CYS D 4 126 ? 332.875 334.311 445.471 1.00 87.32  ? 126 CYS B SG  1 
ATOM 4291 N N   . VAL D 4 127 ? 336.170 335.793 447.244 1.00 84.13  ? 127 VAL B N   1 
ATOM 4292 C CA  . VAL D 4 127 ? 337.540 335.294 447.207 1.00 84.13  ? 127 VAL B CA  1 
ATOM 4293 C C   . VAL D 4 127 ? 337.558 333.770 447.230 1.00 84.13  ? 127 VAL B C   1 
ATOM 4294 O O   . VAL D 4 127 ? 336.830 333.150 448.015 1.00 84.13  ? 127 VAL B O   1 
ATOM 4295 C CB  . VAL D 4 127 ? 338.357 335.912 448.355 1.00 84.13  ? 127 VAL B CB  1 
ATOM 4296 C CG1 . VAL D 4 127 ? 337.637 335.778 449.675 1.00 84.13  ? 127 VAL B CG1 1 
ATOM 4297 C CG2 . VAL D 4 127 ? 339.704 335.259 448.468 1.00 84.13  ? 127 VAL B CG2 1 
ATOM 4298 N N   . PRO D 4 128 ? 338.316 333.123 446.354 1.00 86.01  ? 128 PRO B N   1 
ATOM 4299 C CA  . PRO D 4 128 ? 338.516 331.678 446.484 1.00 86.01  ? 128 PRO B CA  1 
ATOM 4300 C C   . PRO D 4 128 ? 339.726 331.349 447.335 1.00 86.01  ? 128 PRO B C   1 
ATOM 4301 O O   . PRO D 4 128 ? 340.736 332.054 447.269 1.00 86.01  ? 128 PRO B O   1 
ATOM 4302 C CB  . PRO D 4 128 ? 338.707 331.226 445.038 1.00 86.01  ? 128 PRO B CB  1 
ATOM 4303 C CG  . PRO D 4 128 ? 339.291 332.398 444.363 1.00 86.01  ? 128 PRO B CG  1 
ATOM 4304 C CD  . PRO D 4 128 ? 338.842 333.639 445.085 1.00 86.01  ? 128 PRO B CD  1 
ATOM 4305 N N   . GLU D 4 129 ? 339.613 330.283 448.134 1.00 97.07  ? 129 GLU B N   1 
ATOM 4306 C CA  . GLU D 4 129 ? 340.656 329.788 449.035 1.00 97.07  ? 129 GLU B CA  1 
ATOM 4307 C C   . GLU D 4 129 ? 341.105 330.880 450.009 1.00 97.07  ? 129 GLU B C   1 
ATOM 4308 O O   . GLU D 4 129 ? 342.231 331.371 449.976 1.00 97.07  ? 129 GLU B O   1 
ATOM 4309 C CB  . GLU D 4 129 ? 341.838 329.217 448.247 1.00 97.07  ? 129 GLU B CB  1 
ATOM 4310 C CG  . GLU D 4 129 ? 341.432 328.148 447.269 1.00 97.07  ? 129 GLU B CG  1 
ATOM 4311 C CD  . GLU D 4 129 ? 341.011 326.874 447.959 1.00 97.07  ? 129 GLU B CD  1 
ATOM 4312 O OE1 . GLU D 4 129 ? 341.615 326.537 448.997 1.00 97.07  ? 129 GLU B OE1 1 
ATOM 4313 O OE2 . GLU D 4 129 ? 340.074 326.211 447.472 1.00 97.07  ? 129 GLU B OE2 1 
ATOM 4314 N N   . ALA D 4 130 ? 340.166 331.272 450.859 1.00 93.94  ? 130 ALA B N   1 
ATOM 4315 C CA  . ALA D 4 130 ? 340.391 332.369 451.794 1.00 93.94  ? 130 ALA B CA  1 
ATOM 4316 C C   . ALA D 4 130 ? 340.850 331.792 453.122 1.00 93.94  ? 130 ALA B C   1 
ATOM 4317 O O   . ALA D 4 130 ? 340.053 331.550 454.025 1.00 93.94  ? 130 ALA B O   1 
ATOM 4318 C CB  . ALA D 4 130 ? 339.127 333.198 451.956 1.00 93.94  ? 130 ALA B CB  1 
ATOM 4319 N N   . GLU D 4 131 ? 342.152 331.580 453.250 1.00 98.02  ? 131 GLU B N   1 
ATOM 4320 C CA  . GLU D 4 131 ? 342.713 331.079 454.495 1.00 98.02  ? 131 GLU B CA  1 
ATOM 4321 C C   . GLU D 4 131 ? 342.864 332.234 455.470 1.00 98.02  ? 131 GLU B C   1 
ATOM 4322 O O   . GLU D 4 131 ? 343.452 333.260 455.125 1.00 98.02  ? 131 GLU B O   1 
ATOM 4323 C CB  . GLU D 4 131 ? 344.060 330.415 454.241 1.00 98.02  ? 131 GLU B CB  1 
ATOM 4324 C CG  . GLU D 4 131 ? 344.470 329.421 455.304 1.00 98.02  ? 131 GLU B CG  1 
ATOM 4325 C CD  . GLU D 4 131 ? 345.743 328.681 454.947 1.00 98.02  ? 131 GLU B CD  1 
ATOM 4326 O OE1 . GLU D 4 131 ? 346.691 328.700 455.759 1.00 98.02  ? 131 GLU B OE1 1 
ATOM 4327 O OE2 . GLU D 4 131 ? 345.796 328.083 453.852 1.00 98.02  ? 131 GLU B OE2 1 
ATOM 4328 N N   . MET D 4 132 ? 342.333 332.079 456.676 1.00 97.95  ? 132 MET B N   1 
ATOM 4329 C CA  . MET D 4 132 ? 342.442 333.109 457.696 1.00 97.95  ? 132 MET B CA  1 
ATOM 4330 C C   . MET D 4 132 ? 343.395 332.674 458.797 1.00 97.95  ? 132 MET B C   1 
ATOM 4331 O O   . MET D 4 132 ? 343.586 331.486 459.054 1.00 97.95  ? 132 MET B O   1 
ATOM 4332 C CB  . MET D 4 132 ? 341.077 333.434 458.290 1.00 97.95  ? 132 MET B CB  1 
ATOM 4333 C CG  . MET D 4 132 ? 340.142 334.093 457.318 1.00 97.95  ? 132 MET B CG  1 
ATOM 4334 S SD  . MET D 4 132 ? 338.694 334.749 458.142 1.00 97.95  ? 132 MET B SD  1 
ATOM 4335 C CE  . MET D 4 132 ? 337.733 335.262 456.727 1.00 97.95  ? 132 MET B CE  1 
ATOM 4336 N N   . GLY D 4 133 ? 343.983 333.657 459.457 1.00 97.25  ? 133 GLY B N   1 
ATOM 4337 C CA  . GLY D 4 133 ? 344.996 333.413 460.470 1.00 97.25  ? 133 GLY B CA  1 
ATOM 4338 C C   . GLY D 4 133 ? 344.440 333.622 461.862 1.00 97.25  ? 133 GLY B C   1 
ATOM 4339 O O   . GLY D 4 133 ? 343.600 334.494 462.076 1.00 97.25  ? 133 GLY B O   1 
ATOM 4340 N N   . CYS D 4 134 ? 344.918 332.820 462.806 1.00 105.59 ? 134 CYS B N   1 
ATOM 4341 C CA  . CYS D 4 134 ? 344.433 332.896 464.172 1.00 105.59 ? 134 CYS B CA  1 
ATOM 4342 C C   . CYS D 4 134 ? 345.001 334.119 464.879 1.00 105.59 ? 134 CYS B C   1 
ATOM 4343 O O   . CYS D 4 134 ? 345.899 334.798 464.381 1.00 105.59 ? 134 CYS B O   1 
ATOM 4344 C CB  . CYS D 4 134 ? 344.806 331.637 464.948 1.00 105.59 ? 134 CYS B CB  1 
ATOM 4345 S SG  . CYS D 4 134 ? 344.573 331.762 466.731 1.00 105.59 ? 134 CYS B SG  1 
ATOM 4346 N N   . SER D 4 135 ? 344.455 334.400 466.060 1.00 104.62 ? 135 SER B N   1 
ATOM 4347 C CA  . SER D 4 135 ? 345.003 335.469 466.881 1.00 104.62 ? 135 SER B CA  1 
ATOM 4348 C C   . SER D 4 135 ? 346.329 335.062 467.495 1.00 104.62 ? 135 SER B C   1 
ATOM 4349 O O   . SER D 4 135 ? 347.317 335.792 467.384 1.00 104.62 ? 135 SER B O   1 
ATOM 4350 C CB  . SER D 4 135 ? 344.020 335.850 467.979 1.00 104.62 ? 135 SER B CB  1 
ATOM 4351 O OG  . SER D 4 135 ? 343.873 334.785 468.896 1.00 104.62 ? 135 SER B OG  1 
ATOM 4352 N N   . ASN D 4 136 ? 346.369 333.911 468.153 1.00 107.38 ? 136 ASN B N   1 
ATOM 4353 C CA  . ASN D 4 136 ? 347.628 333.402 468.665 1.00 107.38 ? 136 ASN B CA  1 
ATOM 4354 C C   . ASN D 4 136 ? 348.475 332.877 467.518 1.00 107.38 ? 136 ASN B C   1 
ATOM 4355 O O   . ASN D 4 136 ? 347.973 332.207 466.614 1.00 107.38 ? 136 ASN B O   1 
ATOM 4356 C CB  . ASN D 4 136 ? 347.386 332.297 469.683 1.00 107.38 ? 136 ASN B CB  1 
ATOM 4357 C CG  . ASN D 4 136 ? 348.649 331.882 470.382 1.00 107.38 ? 136 ASN B CG  1 
ATOM 4358 O OD1 . ASN D 4 136 ? 349.618 332.635 470.425 1.00 107.38 ? 136 ASN B OD1 1 
ATOM 4359 N ND2 . ASN D 4 136 ? 348.654 330.680 470.935 1.00 107.38 ? 136 ASN B ND2 1 
ATOM 4360 N N   . LEU D 4 137 ? 349.768 333.176 467.560 1.00 102.64 ? 137 LEU B N   1 
ATOM 4361 C CA  . LEU D 4 137 ? 350.643 332.886 466.434 1.00 102.64 ? 137 LEU B CA  1 
ATOM 4362 C C   . LEU D 4 137 ? 350.996 331.414 466.302 1.00 102.64 ? 137 LEU B C   1 
ATOM 4363 O O   . LEU D 4 137 ? 351.532 331.020 465.263 1.00 102.64 ? 137 LEU B O   1 
ATOM 4364 C CB  . LEU D 4 137 ? 351.931 333.696 466.549 1.00 102.64 ? 137 LEU B CB  1 
ATOM 4365 C CG  . LEU D 4 137 ? 351.944 335.107 465.967 1.00 102.64 ? 137 LEU B CG  1 
ATOM 4366 C CD1 . LEU D 4 137 ? 351.255 336.103 466.879 1.00 102.64 ? 137 LEU B CD1 1 
ATOM 4367 C CD2 . LEU D 4 137 ? 353.372 335.533 465.720 1.00 102.64 ? 137 LEU B CD2 1 
ATOM 4368 N N   . ASN D 4 138 ? 350.717 330.592 467.313 1.00 108.22 ? 138 ASN B N   1 
ATOM 4369 C CA  . ASN D 4 138 ? 351.065 329.181 467.266 1.00 108.22 ? 138 ASN B CA  1 
ATOM 4370 C C   . ASN D 4 138 ? 349.880 328.260 467.030 1.00 108.22 ? 138 ASN B C   1 
ATOM 4371 O O   . ASN D 4 138 ? 350.090 327.103 466.658 1.00 108.22 ? 138 ASN B O   1 
ATOM 4372 C CB  . ASN D 4 138 ? 351.759 328.757 468.568 1.00 108.22 ? 138 ASN B CB  1 
ATOM 4373 C CG  . ASN D 4 138 ? 353.003 329.571 468.860 1.00 108.22 ? 138 ASN B CG  1 
ATOM 4374 O OD1 . ASN D 4 138 ? 354.094 329.243 468.399 1.00 108.22 ? 138 ASN B OD1 1 
ATOM 4375 N ND2 . ASN D 4 138 ? 352.847 330.633 469.636 1.00 108.22 ? 138 ASN B ND2 1 
ATOM 4376 N N   . ASN D 4 139 ? 348.656 328.730 467.234 1.00 109.45 ? 139 ASN B N   1 
ATOM 4377 C CA  . ASN D 4 139 ? 347.478 327.892 467.101 1.00 109.45 ? 139 ASN B CA  1 
ATOM 4378 C C   . ASN D 4 139 ? 346.832 328.087 465.736 1.00 109.45 ? 139 ASN B C   1 
ATOM 4379 O O   . ASN D 4 139 ? 347.350 328.775 464.857 1.00 109.45 ? 139 ASN B O   1 
ATOM 4380 C CB  . ASN D 4 139 ? 346.464 328.194 468.203 1.00 109.45 ? 139 ASN B CB  1 
ATOM 4381 C CG  . ASN D 4 139 ? 346.916 327.716 469.561 1.00 109.45 ? 139 ASN B CG  1 
ATOM 4382 O OD1 . ASN D 4 139 ? 347.530 326.659 469.685 1.00 109.45 ? 139 ASN B OD1 1 
ATOM 4383 N ND2 . ASN D 4 139 ? 346.584 328.475 470.595 1.00 109.45 ? 139 ASN B ND2 1 
ATOM 4384 N N   . THR D 4 140 ? 345.674 327.458 465.569 1.00 108.59 ? 140 THR B N   1 
ATOM 4385 C CA  . THR D 4 140 ? 344.794 327.559 464.425 1.00 108.59 ? 140 THR B CA  1 
ATOM 4386 C C   . THR D 4 140 ? 343.364 327.757 464.910 1.00 108.59 ? 140 THR B C   1 
ATOM 4387 O O   . THR D 4 140 ? 342.991 327.194 465.943 1.00 108.59 ? 140 THR B O   1 
ATOM 4388 C CB  . THR D 4 140 ? 344.872 326.295 463.568 1.00 108.59 ? 140 THR B CB  1 
ATOM 4389 O OG1 . THR D 4 140 ? 344.779 325.146 464.417 1.00 108.59 ? 140 THR B OG1 1 
ATOM 4390 C CG2 . THR D 4 140 ? 346.176 326.254 462.797 1.00 108.59 ? 140 THR B CG2 1 
ATOM 4391 N N   . PRO D 4 141 ? 342.550 328.546 464.214 1.00 106.08 ? 141 PRO B N   1 
ATOM 4392 C CA  . PRO D 4 141 ? 341.210 328.842 464.726 1.00 106.08 ? 141 PRO B CA  1 
ATOM 4393 C C   . PRO D 4 141 ? 340.267 327.660 464.585 1.00 106.08 ? 141 PRO B C   1 
ATOM 4394 O O   . PRO D 4 141 ? 340.370 326.861 463.653 1.00 106.08 ? 141 PRO B O   1 
ATOM 4395 C CB  . PRO D 4 141 ? 340.757 330.015 463.857 1.00 106.08 ? 141 PRO B CB  1 
ATOM 4396 C CG  . PRO D 4 141 ? 341.493 329.832 462.599 1.00 106.08 ? 141 PRO B CG  1 
ATOM 4397 C CD  . PRO D 4 141 ? 342.821 329.264 462.959 1.00 106.08 ? 141 PRO B CD  1 
ATOM 4398 N N   . GLU D 4 142 ? 339.334 327.558 465.529 1.00 108.27 ? 142 GLU B N   1 
ATOM 4399 C CA  . GLU D 4 142 ? 338.400 326.444 465.562 1.00 108.27 ? 142 GLU B CA  1 
ATOM 4400 C C   . GLU D 4 142 ? 337.322 326.615 464.498 1.00 108.27 ? 142 GLU B C   1 
ATOM 4401 O O   . GLU D 4 142 ? 337.260 327.623 463.791 1.00 108.27 ? 142 GLU B O   1 
ATOM 4402 C CB  . GLU D 4 142 ? 337.767 326.313 466.941 1.00 108.27 ? 142 GLU B CB  1 
ATOM 4403 C CG  . GLU D 4 142 ? 336.909 327.491 467.330 1.00 108.27 ? 142 GLU B CG  1 
ATOM 4404 C CD  . GLU D 4 142 ? 335.971 327.167 468.471 1.00 108.27 ? 142 GLU B CD  1 
ATOM 4405 O OE1 . GLU D 4 142 ? 335.761 328.036 469.342 1.00 108.27 ? 142 GLU B OE1 1 
ATOM 4406 O OE2 . GLU D 4 142 ? 335.437 326.039 468.490 1.00 108.27 ? 142 GLU B OE2 1 
ATOM 4407 N N   . PHE D 4 143 ? 336.438 325.620 464.397 1.00 106.70 ? 143 PHE B N   1 
ATOM 4408 C CA  . PHE D 4 143 ? 335.469 325.609 463.308 1.00 106.70 ? 143 PHE B CA  1 
ATOM 4409 C C   . PHE D 4 143 ? 334.331 326.586 463.543 1.00 106.70 ? 143 PHE B C   1 
ATOM 4410 O O   . PHE D 4 143 ? 333.864 327.233 462.600 1.00 106.70 ? 143 PHE B O   1 
ATOM 4411 C CB  . PHE D 4 143 ? 334.899 324.213 463.108 1.00 106.70 ? 143 PHE B CB  1 
ATOM 4412 C CG  . PHE D 4 143 ? 333.802 324.168 462.100 1.00 106.70 ? 143 PHE B CG  1 
ATOM 4413 C CD1 . PHE D 4 143 ? 334.075 324.395 460.765 1.00 106.70 ? 143 PHE B CD1 1 
ATOM 4414 C CD2 . PHE D 4 143 ? 332.495 323.929 462.483 1.00 106.70 ? 143 PHE B CD2 1 
ATOM 4415 C CE1 . PHE D 4 143 ? 333.068 324.365 459.825 1.00 106.70 ? 143 PHE B CE1 1 
ATOM 4416 C CE2 . PHE D 4 143 ? 331.480 323.899 461.546 1.00 106.70 ? 143 PHE B CE2 1 
ATOM 4417 C CZ  . PHE D 4 143 ? 331.768 324.117 460.216 1.00 106.70 ? 143 PHE B CZ  1 
ATOM 4418 N N   . SER D 4 144 ? 333.878 326.718 464.788 1.00 106.16 ? 144 SER B N   1 
ATOM 4419 C CA  . SER D 4 144 ? 332.725 327.562 465.070 1.00 106.16 ? 144 SER B CA  1 
ATOM 4420 C C   . SER D 4 144 ? 333.045 329.048 465.004 1.00 106.16 ? 144 SER B C   1 
ATOM 4421 O O   . SER D 4 144 ? 332.136 329.867 465.153 1.00 106.16 ? 144 SER B O   1 
ATOM 4422 C CB  . SER D 4 144 ? 332.151 327.235 466.443 1.00 106.16 ? 144 SER B CB  1 
ATOM 4423 O OG  . SER D 4 144 ? 331.275 328.262 466.864 1.00 106.16 ? 144 SER B OG  1 
ATOM 4424 N N   . GLU D 4 145 ? 334.304 329.415 464.803 1.00 106.13 ? 145 GLU B N   1 
ATOM 4425 C CA  . GLU D 4 145 ? 334.668 330.803 464.598 1.00 106.13 ? 145 GLU B CA  1 
ATOM 4426 C C   . GLU D 4 145 ? 334.852 331.158 463.134 1.00 106.13 ? 145 GLU B C   1 
ATOM 4427 O O   . GLU D 4 145 ? 334.614 332.310 462.762 1.00 106.13 ? 145 GLU B O   1 
ATOM 4428 C CB  . GLU D 4 145 ? 335.949 331.128 465.362 1.00 106.13 ? 145 GLU B CB  1 
ATOM 4429 C CG  . GLU D 4 145 ? 335.723 331.341 466.834 1.00 106.13 ? 145 GLU B CG  1 
ATOM 4430 C CD  . GLU D 4 145 ? 335.104 332.687 467.133 1.00 106.13 ? 145 GLU B CD  1 
ATOM 4431 O OE1 . GLU D 4 145 ? 335.214 333.597 466.287 1.00 106.13 ? 145 GLU B OE1 1 
ATOM 4432 O OE2 . GLU D 4 145 ? 334.503 332.839 468.215 1.00 106.13 ? 145 GLU B OE2 1 
ATOM 4433 N N   . LEU D 4 146 ? 335.255 330.206 462.294 1.00 102.27 ? 146 LEU B N   1 
ATOM 4434 C CA  . LEU D 4 146 ? 335.494 330.528 460.895 1.00 102.27 ? 146 LEU B CA  1 
ATOM 4435 C C   . LEU D 4 146 ? 334.201 330.666 460.112 1.00 102.27 ? 146 LEU B C   1 
ATOM 4436 O O   . LEU D 4 146 ? 334.131 331.456 459.166 1.00 102.27 ? 146 LEU B O   1 
ATOM 4437 C CB  . LEU D 4 146 ? 336.374 329.471 460.246 1.00 102.27 ? 146 LEU B CB  1 
ATOM 4438 C CG  . LEU D 4 146 ? 337.856 329.633 460.539 1.00 102.27 ? 146 LEU B CG  1 
ATOM 4439 C CD1 . LEU D 4 146 ? 338.642 328.525 459.882 1.00 102.27 ? 146 LEU B CD1 1 
ATOM 4440 C CD2 . LEU D 4 146 ? 338.317 330.975 460.036 1.00 102.27 ? 146 LEU B CD2 1 
ATOM 4441 N N   . SER D 4 147 ? 333.174 329.907 460.471 1.00 104.31 ? 147 SER B N   1 
ATOM 4442 C CA  . SER D 4 147 ? 331.931 329.934 459.718 1.00 104.31 ? 147 SER B CA  1 
ATOM 4443 C C   . SER D 4 147 ? 330.762 329.802 460.671 1.00 104.31 ? 147 SER B C   1 
ATOM 4444 O O   . SER D 4 147 ? 330.529 328.724 461.222 1.00 104.31 ? 147 SER B O   1 
ATOM 4445 C CB  . SER D 4 147 ? 331.887 328.811 458.689 1.00 104.31 ? 147 SER B CB  1 
ATOM 4446 O OG  . SER D 4 147 ? 331.345 327.639 459.266 1.00 104.31 ? 147 SER B OG  1 
ATOM 4447 N N   . GLY D 4 148 ? 330.021 330.890 460.855 1.00 104.73 ? 148 GLY B N   1 
ATOM 4448 C CA  . GLY D 4 148 ? 328.724 330.788 461.482 1.00 104.73 ? 148 GLY B CA  1 
ATOM 4449 C C   . GLY D 4 148 ? 327.774 330.134 460.505 1.00 104.73 ? 148 GLY B C   1 
ATOM 4450 O O   . GLY D 4 148 ? 327.724 330.507 459.328 1.00 104.73 ? 148 GLY B O   1 
ATOM 4451 N N   . GLY D 4 149 ? 327.046 329.130 460.979 1.00 109.98 ? 149 GLY B N   1 
ATOM 4452 C CA  . GLY D 4 149 ? 326.055 328.468 460.159 1.00 109.98 ? 149 GLY B CA  1 
ATOM 4453 C C   . GLY D 4 149 ? 324.921 329.402 459.801 1.00 109.98 ? 149 GLY B C   1 
ATOM 4454 O O   . GLY D 4 149 ? 324.193 329.857 460.689 1.00 109.98 ? 149 GLY B O   1 
ATOM 4455 N N   . ASP D 4 150 ? 324.786 329.686 458.496 1.00 112.35 ? 150 ASP B N   1 
ATOM 4456 C CA  . ASP D 4 150 ? 323.883 330.647 457.851 1.00 112.35 ? 150 ASP B CA  1 
ATOM 4457 C C   . ASP D 4 150 ? 323.732 331.963 458.606 1.00 112.35 ? 150 ASP B C   1 
ATOM 4458 O O   . ASP D 4 150 ? 322.641 332.536 458.664 1.00 112.35 ? 150 ASP B O   1 
ATOM 4459 C CB  . ASP D 4 150 ? 322.498 330.028 457.579 1.00 112.35 ? 150 ASP B CB  1 
ATOM 4460 C CG  . ASP D 4 150 ? 321.835 329.450 458.815 1.00 112.35 ? 150 ASP B CG  1 
ATOM 4461 O OD1 . ASP D 4 150 ? 321.222 330.214 459.587 1.00 112.35 ? 150 ASP B OD1 1 
ATOM 4462 O OD2 . ASP D 4 150 ? 321.942 328.224 459.022 1.00 112.35 ? 150 ASP B OD2 1 
ATOM 4463 N N   . SER D 4 151 ? 324.832 332.462 459.159 1.00 103.59 ? 151 SER B N   1 
ATOM 4464 C CA  . SER D 4 151 ? 324.843 333.721 459.883 1.00 103.59 ? 151 SER B CA  1 
ATOM 4465 C C   . SER D 4 151 ? 326.154 334.421 459.572 1.00 103.59 ? 151 SER B C   1 
ATOM 4466 O O   . SER D 4 151 ? 327.175 333.769 459.344 1.00 103.59 ? 151 SER B O   1 
ATOM 4467 C CB  . SER D 4 151 ? 324.693 333.514 461.393 1.00 103.59 ? 151 SER B CB  1 
ATOM 4468 O OG  . SER D 4 151 ? 323.683 332.565 461.682 1.00 103.59 ? 151 SER B OG  1 
ATOM 4469 N N   . ALA D 4 152 ? 326.120 335.744 459.557 1.00 93.07  ? 152 ALA B N   1 
ATOM 4470 C CA  . ALA D 4 152 ? 327.298 336.510 459.195 1.00 93.07  ? 152 ALA B CA  1 
ATOM 4471 C C   . ALA D 4 152 ? 328.246 336.629 460.373 1.00 93.07  ? 152 ALA B C   1 
ATOM 4472 O O   . ALA D 4 152 ? 327.883 337.165 461.421 1.00 93.07  ? 152 ALA B O   1 
ATOM 4473 C CB  . ALA D 4 152 ? 326.896 337.898 458.716 1.00 93.07  ? 152 ALA B CB  1 
ATOM 4474 N N   . ARG D 4 153 ? 329.461 336.135 460.201 1.00 94.39  ? 153 ARG B N   1 
ATOM 4475 C CA  . ARG D 4 153 ? 330.514 336.564 461.096 1.00 94.39  ? 153 ARG B CA  1 
ATOM 4476 C C   . ARG D 4 153 ? 330.881 338.006 460.775 1.00 94.39  ? 153 ARG B C   1 
ATOM 4477 O O   . ARG D 4 153 ? 330.688 338.482 459.656 1.00 94.39  ? 153 ARG B O   1 
ATOM 4478 C CB  . ARG D 4 153 ? 331.736 335.666 460.963 1.00 94.39  ? 153 ARG B CB  1 
ATOM 4479 C CG  . ARG D 4 153 ? 331.624 334.367 461.713 1.00 94.39  ? 153 ARG B CG  1 
ATOM 4480 C CD  . ARG D 4 153 ? 331.489 334.615 463.193 1.00 94.39  ? 153 ARG B CD  1 
ATOM 4481 N NE  . ARG D 4 153 ? 330.910 333.461 463.857 1.00 94.39  ? 153 ARG B NE  1 
ATOM 4482 C CZ  . ARG D 4 153 ? 329.605 333.244 463.955 1.00 94.39  ? 153 ARG B CZ  1 
ATOM 4483 N NH1 . ARG D 4 153 ? 329.153 332.164 464.575 1.00 94.39  ? 153 ARG B NH1 1 
ATOM 4484 N NH2 . ARG D 4 153 ? 328.749 334.112 463.437 1.00 94.39  ? 153 ARG B NH2 1 
ATOM 4485 N N   . MET D 4 154 ? 331.415 338.709 461.764 1.00 89.29  ? 154 MET B N   1 
ATOM 4486 C CA  . MET D 4 154 ? 331.683 340.129 461.621 1.00 89.29  ? 154 MET B CA  1 
ATOM 4487 C C   . MET D 4 154 ? 333.156 340.420 461.820 1.00 89.29  ? 154 MET B C   1 
ATOM 4488 O O   . MET D 4 154 ? 333.803 339.833 462.687 1.00 89.29  ? 154 MET B O   1 
ATOM 4489 C CB  . MET D 4 154 ? 330.870 340.947 462.611 1.00 89.29  ? 154 MET B CB  1 
ATOM 4490 C CG  . MET D 4 154 ? 329.386 340.850 462.378 1.00 89.29  ? 154 MET B CG  1 
ATOM 4491 S SD  . MET D 4 154 ? 328.420 341.940 463.427 1.00 89.29  ? 154 MET B SD  1 
ATOM 4492 C CE  . MET D 4 154 ? 326.766 341.405 463.001 1.00 89.29  ? 154 MET B CE  1 
ATOM 4493 N N   . PHE D 4 155 ? 333.673 341.337 461.013 1.00 90.13  ? 155 PHE B N   1 
ATOM 4494 C CA  . PHE D 4 155 ? 334.993 341.885 461.248 1.00 90.13  ? 155 PHE B CA  1 
ATOM 4495 C C   . PHE D 4 155 ? 334.966 342.801 462.464 1.00 90.13  ? 155 PHE B C   1 
ATOM 4496 O O   . PHE D 4 155 ? 333.911 343.169 462.981 1.00 90.13  ? 155 PHE B O   1 
ATOM 4497 C CB  . PHE D 4 155 ? 335.474 342.667 460.032 1.00 90.13  ? 155 PHE B CB  1 
ATOM 4498 C CG  . PHE D 4 155 ? 335.898 341.810 458.883 1.00 90.13  ? 155 PHE B CG  1 
ATOM 4499 C CD1 . PHE D 4 155 ? 336.880 340.861 459.041 1.00 90.13  ? 155 PHE B CD1 1 
ATOM 4500 C CD2 . PHE D 4 155 ? 335.325 341.968 457.640 1.00 90.13  ? 155 PHE B CD2 1 
ATOM 4501 C CE1 . PHE D 4 155 ? 337.276 340.082 457.981 1.00 90.13  ? 155 PHE B CE1 1 
ATOM 4502 C CE2 . PHE D 4 155 ? 335.719 341.189 456.580 1.00 90.13  ? 155 PHE B CE2 1 
ATOM 4503 C CZ  . PHE D 4 155 ? 336.692 340.247 456.752 1.00 90.13  ? 155 PHE B CZ  1 
ATOM 4504 N N   . THR D 4 156 ? 336.147 343.172 462.925 1.00 107.68 ? 156 THR B N   1 
ATOM 4505 C CA  . THR D 4 156 ? 336.280 344.185 463.954 1.00 107.68 ? 156 THR B CA  1 
ATOM 4506 C C   . THR D 4 156 ? 337.073 345.354 463.397 1.00 107.68 ? 156 THR B C   1 
ATOM 4507 O O   . THR D 4 156 ? 337.747 345.245 462.374 1.00 107.68 ? 156 THR B O   1 
ATOM 4508 C CB  . THR D 4 156 ? 336.974 343.633 465.200 1.00 107.68 ? 156 THR B CB  1 
ATOM 4509 O OG1 . THR D 4 156 ? 338.285 343.185 464.849 1.00 107.68 ? 156 THR B OG1 1 
ATOM 4510 C CG2 . THR D 4 156 ? 336.193 342.479 465.781 1.00 107.68 ? 156 THR B CG2 1 
ATOM 4511 N N   . ASP D 4 157 ? 336.995 346.482 464.086 1.00 116.03 ? 157 ASP B N   1 
ATOM 4512 C CA  . ASP D 4 157 ? 337.765 347.654 463.714 1.00 116.03 ? 157 ASP B CA  1 
ATOM 4513 C C   . ASP D 4 157 ? 338.996 347.844 464.581 1.00 116.03 ? 157 ASP B C   1 
ATOM 4514 O O   . ASP D 4 157 ? 339.723 348.820 464.392 1.00 116.03 ? 157 ASP B O   1 
ATOM 4515 C CB  . ASP D 4 157 ? 336.888 348.901 463.781 1.00 116.03 ? 157 ASP B CB  1 
ATOM 4516 C CG  . ASP D 4 157 ? 336.033 348.935 465.021 1.00 116.03 ? 157 ASP B CG  1 
ATOM 4517 O OD1 . ASP D 4 157 ? 336.036 347.938 465.767 1.00 116.03 ? 157 ASP B OD1 1 
ATOM 4518 O OD2 . ASP D 4 157 ? 335.357 349.957 465.250 1.00 116.03 ? 157 ASP B OD2 1 
ATOM 4519 N N   . THR D 4 158 ? 339.232 346.955 465.539 1.00 118.72 ? 158 THR B N   1 
ATOM 4520 C CA  . THR D 4 158 ? 340.437 346.963 466.351 1.00 118.72 ? 158 THR B CA  1 
ATOM 4521 C C   . THR D 4 158 ? 341.184 345.656 466.146 1.00 118.72 ? 158 THR B C   1 
ATOM 4522 O O   . THR D 4 158 ? 340.840 344.845 465.286 1.00 118.72 ? 158 THR B O   1 
ATOM 4523 C CB  . THR D 4 158 ? 340.125 347.135 467.839 1.00 118.72 ? 158 THR B CB  1 
ATOM 4524 O OG1 . THR D 4 158 ? 339.693 345.881 468.372 1.00 118.72 ? 158 THR B OG1 1 
ATOM 4525 C CG2 . THR D 4 158 ? 339.038 348.162 468.056 1.00 118.72 ? 158 THR B CG2 1 
ATOM 4526 N N   . GLN D 4 159 ? 342.218 345.455 466.951 1.00 116.89 ? 159 GLN B N   1 
ATOM 4527 C CA  . GLN D 4 159 ? 342.922 344.187 466.922 1.00 116.89 ? 159 GLN B CA  1 
ATOM 4528 C C   . GLN D 4 159 ? 342.287 343.202 467.889 1.00 116.89 ? 159 GLN B C   1 
ATOM 4529 O O   . GLN D 4 159 ? 341.821 343.563 468.971 1.00 116.89 ? 159 GLN B O   1 
ATOM 4530 C CB  . GLN D 4 159 ? 344.387 344.369 467.292 1.00 116.89 ? 159 GLN B CB  1 
ATOM 4531 C CG  . GLN D 4 159 ? 345.116 345.381 466.459 1.00 116.89 ? 159 GLN B CG  1 
ATOM 4532 C CD  . GLN D 4 159 ? 346.608 345.258 466.610 1.00 116.89 ? 159 GLN B CD  1 
ATOM 4533 O OE1 . GLN D 4 159 ? 347.335 346.241 466.511 1.00 116.89 ? 159 GLN B OE1 1 
ATOM 4534 N NE2 . GLN D 4 159 ? 347.076 344.043 466.857 1.00 116.89 ? 159 GLN B NE2 1 
ATOM 4535 N N   . VAL D 4 160 ? 342.287 341.941 467.494 1.00 112.64 ? 160 VAL B N   1 
ATOM 4536 C CA  . VAL D 4 160 ? 341.870 340.852 468.363 1.00 112.64 ? 160 VAL B CA  1 
ATOM 4537 C C   . VAL D 4 160 ? 343.040 340.555 469.283 1.00 112.64 ? 160 VAL B C   1 
ATOM 4538 O O   . VAL D 4 160 ? 344.200 340.627 468.861 1.00 112.64 ? 160 VAL B O   1 
ATOM 4539 C CB  . VAL D 4 160 ? 341.457 339.619 467.537 1.00 112.64 ? 160 VAL B CB  1 
ATOM 4540 C CG1 . VAL D 4 160 ? 340.962 338.491 468.423 1.00 112.64 ? 160 VAL B CG1 1 
ATOM 4541 C CG2 . VAL D 4 160 ? 340.393 340.002 466.545 1.00 112.64 ? 160 VAL B CG2 1 
ATOM 4542 N N   . GLY D 4 161 ? 342.744 340.250 470.546 1.00 118.69 ? 161 GLY B N   1 
ATOM 4543 C CA  . GLY D 4 161 ? 343.783 340.122 471.543 1.00 118.69 ? 161 GLY B CA  1 
ATOM 4544 C C   . GLY D 4 161 ? 344.681 338.921 471.326 1.00 118.69 ? 161 GLY B C   1 
ATOM 4545 O O   . GLY D 4 161 ? 344.468 338.084 470.451 1.00 118.69 ? 161 GLY B O   1 
ATOM 4546 N N   . GLU D 4 162 ? 345.734 338.865 472.134 1.00 121.75 ? 162 GLU B N   1 
ATOM 4547 C CA  . GLU D 4 162 ? 346.674 337.757 472.096 1.00 121.75 ? 162 GLU B CA  1 
ATOM 4548 C C   . GLU D 4 162 ? 346.373 336.720 473.161 1.00 121.75 ? 162 GLU B C   1 
ATOM 4549 O O   . GLU D 4 162 ? 346.637 335.531 472.955 1.00 121.75 ? 162 GLU B O   1 
ATOM 4550 C CB  . GLU D 4 162 ? 348.099 338.284 472.274 1.00 121.75 ? 162 GLU B CB  1 
ATOM 4551 C CG  . GLU D 4 162 ? 349.187 337.276 471.988 1.00 121.75 ? 162 GLU B CG  1 
ATOM 4552 C CD  . GLU D 4 162 ? 349.224 336.865 470.536 1.00 121.75 ? 162 GLU B CD  1 
ATOM 4553 O OE1 . GLU D 4 162 ? 348.949 337.717 469.667 1.00 121.75 ? 162 GLU B OE1 1 
ATOM 4554 O OE2 . GLU D 4 162 ? 349.523 335.685 470.261 1.00 121.75 ? 162 GLU B OE2 1 
ATOM 4555 N N   . SER D 4 163 ? 345.783 337.142 474.277 1.00 133.94 ? 163 SER B N   1 
ATOM 4556 C CA  . SER D 4 163 ? 345.595 336.255 475.414 1.00 133.94 ? 163 SER B CA  1 
ATOM 4557 C C   . SER D 4 163 ? 344.512 335.208 475.188 1.00 133.94 ? 163 SER B C   1 
ATOM 4558 O O   . SER D 4 163 ? 344.429 334.255 475.967 1.00 133.94 ? 163 SER B O   1 
ATOM 4559 C CB  . SER D 4 163 ? 345.267 337.076 476.657 1.00 133.94 ? 163 SER B CB  1 
ATOM 4560 O OG  . SER D 4 163 ? 343.885 337.359 476.716 1.00 133.94 ? 163 SER B OG  1 
ATOM 4561 N N   . ASN D 4 164 ? 343.685 335.352 474.158 1.00 122.76 ? 164 ASN B N   1 
ATOM 4562 C CA  . ASN D 4 164 ? 342.679 334.339 473.880 1.00 122.76 ? 164 ASN B CA  1 
ATOM 4563 C C   . ASN D 4 164 ? 343.306 333.153 473.160 1.00 122.76 ? 164 ASN B C   1 
ATOM 4564 O O   . ASN D 4 164 ? 344.351 333.269 472.515 1.00 122.76 ? 164 ASN B O   1 
ATOM 4565 C CB  . ASN D 4 164 ? 341.535 334.920 473.053 1.00 122.76 ? 164 ASN B CB  1 
ATOM 4566 C CG  . ASN D 4 164 ? 342.020 335.696 471.858 1.00 122.76 ? 164 ASN B CG  1 
ATOM 4567 O OD1 . ASN D 4 164 ? 343.219 335.812 471.626 1.00 122.76 ? 164 ASN B OD1 1 
ATOM 4568 N ND2 . ASN D 4 164 ? 341.089 336.241 471.090 1.00 122.76 ? 164 ASN B ND2 1 
ATOM 4569 N N   . ALA D 4 165 ? 342.655 331.998 473.280 1.00 114.15 ? 165 ALA B N   1 
ATOM 4570 C CA  . ALA D 4 165 ? 343.250 330.764 472.785 1.00 114.15 ? 165 ALA B CA  1 
ATOM 4571 C C   . ALA D 4 165 ? 343.062 330.617 471.282 1.00 114.15 ? 165 ALA B C   1 
ATOM 4572 O O   . ALA D 4 165 ? 344.036 330.587 470.521 1.00 114.15 ? 165 ALA B O   1 
ATOM 4573 C CB  . ALA D 4 165 ? 342.649 329.567 473.519 1.00 114.15 ? 165 ALA B CB  1 
ATOM 4574 N N   . LYS D 4 166 ? 341.811 330.517 470.832 1.00 105.58 ? 166 LYS B N   1 
ATOM 4575 C CA  . LYS D 4 166 ? 341.525 330.197 469.433 1.00 105.58 ? 166 LYS B CA  1 
ATOM 4576 C C   . LYS D 4 166 ? 340.434 331.151 468.949 1.00 105.58 ? 166 LYS B C   1 
ATOM 4577 O O   . LYS D 4 166 ? 339.244 330.880 469.110 1.00 105.58 ? 166 LYS B O   1 
ATOM 4578 C CB  . LYS D 4 166 ? 341.098 328.746 469.271 1.00 105.58 ? 166 LYS B CB  1 
ATOM 4579 C CG  . LYS D 4 166 ? 342.171 327.731 469.602 1.00 105.58 ? 166 LYS B CG  1 
ATOM 4580 C CD  . LYS D 4 166 ? 341.585 326.344 469.725 1.00 105.58 ? 166 LYS B CD  1 
ATOM 4581 C CE  . LYS D 4 166 ? 341.118 325.847 468.376 1.00 105.58 ? 166 LYS B CE  1 
ATOM 4582 N NZ  . LYS D 4 166 ? 340.546 324.479 468.444 1.00 105.58 ? 166 LYS B NZ  1 
ATOM 4583 N N   . LYS D 4 167 ? 340.853 332.260 468.353 1.00 107.09 ? 167 LYS B N   1 
ATOM 4584 C CA  . LYS D 4 167 ? 339.924 333.198 467.746 1.00 107.09 ? 167 LYS B CA  1 
ATOM 4585 C C   . LYS D 4 167 ? 340.569 333.789 466.505 1.00 107.09 ? 167 LYS B C   1 
ATOM 4586 O O   . LYS D 4 167 ? 341.784 333.976 466.441 1.00 107.09 ? 167 LYS B O   1 
ATOM 4587 C CB  . LYS D 4 167 ? 339.512 334.305 468.717 1.00 107.09 ? 167 LYS B CB  1 
ATOM 4588 C CG  . LYS D 4 167 ? 338.224 334.009 469.458 1.00 107.09 ? 167 LYS B CG  1 
ATOM 4589 C CD  . LYS D 4 167 ? 337.916 335.066 470.500 1.00 107.09 ? 167 LYS B CD  1 
ATOM 4590 C CE  . LYS D 4 167 ? 337.695 336.422 469.860 1.00 107.09 ? 167 LYS B CE  1 
ATOM 4591 N NZ  . LYS D 4 167 ? 337.322 337.452 470.865 1.00 107.09 ? 167 LYS B NZ  1 
ATOM 4592 N N   . VAL D 4 168 ? 339.737 334.078 465.516 1.00 102.99 ? 168 VAL B N   1 
ATOM 4593 C CA  . VAL D 4 168 ? 340.222 334.507 464.212 1.00 102.99 ? 168 VAL B CA  1 
ATOM 4594 C C   . VAL D 4 168 ? 340.673 335.955 464.300 1.00 102.99 ? 168 VAL B C   1 
ATOM 4595 O O   . VAL D 4 168 ? 339.981 336.796 464.881 1.00 102.99 ? 168 VAL B O   1 
ATOM 4596 C CB  . VAL D 4 168 ? 339.131 334.328 463.150 1.00 102.99 ? 168 VAL B CB  1 
ATOM 4597 C CG1 . VAL D 4 168 ? 339.695 334.531 461.766 1.00 102.99 ? 168 VAL B CG1 1 
ATOM 4598 C CG2 . VAL D 4 168 ? 338.513 332.961 463.277 1.00 102.99 ? 168 VAL B CG2 1 
ATOM 4599 N N   . GLN D 4 169 ? 341.843 336.246 463.741 1.00 102.50 ? 169 GLN B N   1 
ATOM 4600 C CA  . GLN D 4 169 ? 342.340 337.615 463.690 1.00 102.50 ? 169 GLN B CA  1 
ATOM 4601 C C   . GLN D 4 169 ? 341.522 338.403 462.678 1.00 102.50 ? 169 GLN B C   1 
ATOM 4602 O O   . GLN D 4 169 ? 341.654 338.199 461.469 1.00 102.50 ? 169 GLN B O   1 
ATOM 4603 C CB  . GLN D 4 169 ? 343.819 337.625 463.328 1.00 102.50 ? 169 GLN B CB  1 
ATOM 4604 C CG  . GLN D 4 169 ? 344.387 339.007 463.134 1.00 102.50 ? 169 GLN B CG  1 
ATOM 4605 C CD  . GLN D 4 169 ? 344.083 339.909 464.300 1.00 102.50 ? 169 GLN B CD  1 
ATOM 4606 O OE1 . GLN D 4 169 ? 343.244 340.801 464.205 1.00 102.50 ? 169 GLN B OE1 1 
ATOM 4607 N NE2 . GLN D 4 169 ? 344.756 339.677 465.416 1.00 102.50 ? 169 GLN B NE2 1 
ATOM 4608 N N   . THR D 4 170 ? 340.674 339.304 463.166 1.00 104.13 ? 170 THR B N   1 
ATOM 4609 C CA  . THR D 4 170 ? 339.725 339.980 462.295 1.00 104.13 ? 170 THR B CA  1 
ATOM 4610 C C   . THR D 4 170 ? 339.936 341.485 462.265 1.00 104.13 ? 170 THR B C   1 
ATOM 4611 O O   . THR D 4 170 ? 338.972 342.245 462.389 1.00 104.13 ? 170 THR B O   1 
ATOM 4612 C CB  . THR D 4 170 ? 338.295 339.690 462.734 1.00 104.13 ? 170 THR B CB  1 
ATOM 4613 O OG1 . THR D 4 170 ? 338.144 340.047 464.110 1.00 104.13 ? 170 THR B OG1 1 
ATOM 4614 C CG2 . THR D 4 170 ? 337.981 338.227 462.570 1.00 104.13 ? 170 THR B CG2 1 
ATOM 4615 N N   . ALA D 4 171 ? 341.176 341.933 462.117 1.00 101.86 ? 171 ALA B N   1 
ATOM 4616 C CA  . ALA D 4 171 ? 341.432 343.345 461.878 1.00 101.86 ? 171 ALA B CA  1 
ATOM 4617 C C   . ALA D 4 171 ? 341.053 343.663 460.440 1.00 101.86 ? 171 ALA B C   1 
ATOM 4618 O O   . ALA D 4 171 ? 341.517 342.995 459.512 1.00 101.86 ? 171 ALA B O   1 
ATOM 4619 C CB  . ALA D 4 171 ? 342.893 343.684 462.143 1.00 101.86 ? 171 ALA B CB  1 
ATOM 4620 N N   . VAL D 4 172 ? 340.211 344.678 460.254 1.00 94.25  ? 172 VAL B N   1 
ATOM 4621 C CA  . VAL D 4 172 ? 339.593 344.897 458.954 1.00 94.25  ? 172 VAL B CA  1 
ATOM 4622 C C   . VAL D 4 172 ? 340.572 345.442 457.920 1.00 94.25  ? 172 VAL B C   1 
ATOM 4623 O O   . VAL D 4 172 ? 340.466 345.087 456.741 1.00 94.25  ? 172 VAL B O   1 
ATOM 4624 C CB  . VAL D 4 172 ? 338.353 345.792 459.141 1.00 94.25  ? 172 VAL B CB  1 
ATOM 4625 C CG1 . VAL D 4 172 ? 338.721 347.142 459.726 1.00 94.25  ? 172 VAL B CG1 1 
ATOM 4626 C CG2 . VAL D 4 172 ? 337.575 345.950 457.849 1.00 94.25  ? 172 VAL B CG2 1 
ATOM 4627 N N   . TRP D 4 173 ? 341.577 346.220 458.324 1.00 90.60  ? 173 TRP B N   1 
ATOM 4628 C CA  . TRP D 4 173 ? 342.505 346.789 457.354 1.00 90.60  ? 173 TRP B CA  1 
ATOM 4629 C C   . TRP D 4 173 ? 343.487 345.777 456.790 1.00 90.60  ? 173 TRP B C   1 
ATOM 4630 O O   . TRP D 4 173 ? 344.267 346.131 455.905 1.00 90.60  ? 173 TRP B O   1 
ATOM 4631 C CB  . TRP D 4 173 ? 343.289 347.939 457.972 1.00 90.60  ? 173 TRP B CB  1 
ATOM 4632 C CG  . TRP D 4 173 ? 343.977 347.568 459.220 1.00 90.60  ? 173 TRP B CG  1 
ATOM 4633 C CD1 . TRP D 4 173 ? 345.189 346.971 459.341 1.00 90.60  ? 173 TRP B CD1 1 
ATOM 4634 C CD2 . TRP D 4 173 ? 343.502 347.782 460.542 1.00 90.60  ? 173 TRP B CD2 1 
ATOM 4635 N NE1 . TRP D 4 173 ? 345.498 346.789 460.661 1.00 90.60  ? 173 TRP B NE1 1 
ATOM 4636 C CE2 . TRP D 4 173 ? 344.474 347.284 461.420 1.00 90.60  ? 173 TRP B CE2 1 
ATOM 4637 C CE3 . TRP D 4 173 ? 342.345 348.348 461.069 1.00 90.60  ? 173 TRP B CE3 1 
ATOM 4638 C CZ2 . TRP D 4 173 ? 344.326 347.331 462.794 1.00 90.60  ? 173 TRP B CZ2 1 
ATOM 4639 C CZ3 . TRP D 4 173 ? 342.199 348.396 462.431 1.00 90.60  ? 173 TRP B CZ3 1 
ATOM 4640 C CH2 . TRP D 4 173 ? 343.182 347.890 463.281 1.00 90.60  ? 173 TRP B CH2 1 
ATOM 4641 N N   . ASN D 4 174 ? 343.491 344.546 457.288 1.00 93.52  ? 174 ASN B N   1 
ATOM 4642 C CA  . ASN D 4 174 ? 344.287 343.488 456.701 1.00 93.52  ? 174 ASN B CA  1 
ATOM 4643 C C   . ASN D 4 174 ? 343.457 342.308 456.236 1.00 93.52  ? 174 ASN B C   1 
ATOM 4644 O O   . ASN D 4 174 ? 344.032 341.323 455.765 1.00 93.52  ? 174 ASN B O   1 
ATOM 4645 C CB  . ASN D 4 174 ? 345.354 343.017 457.681 1.00 93.52  ? 174 ASN B CB  1 
ATOM 4646 C CG  . ASN D 4 174 ? 346.589 343.862 457.614 1.00 93.52  ? 174 ASN B CG  1 
ATOM 4647 O OD1 . ASN D 4 174 ? 346.992 344.476 458.595 1.00 93.52  ? 174 ASN B OD1 1 
ATOM 4648 N ND2 . ASN D 4 174 ? 347.197 343.911 456.442 1.00 93.52  ? 174 ASN B ND2 1 
ATOM 4649 N N   . ALA D 4 175 ? 342.133 342.377 456.382 1.00 90.36  ? 175 ALA B N   1 
ATOM 4650 C CA  . ALA D 4 175 ? 341.161 341.437 455.822 1.00 90.36  ? 175 ALA B CA  1 
ATOM 4651 C C   . ALA D 4 175 ? 341.362 340.004 456.291 1.00 90.36  ? 175 ALA B C   1 
ATOM 4652 O O   . ALA D 4 175 ? 340.948 339.069 455.609 1.00 90.36  ? 175 ALA B O   1 
ATOM 4653 C CB  . ALA D 4 175 ? 341.157 341.485 454.292 1.00 90.36  ? 175 ALA B CB  1 
ATOM 4654 N N   . GLY D 4 176 ? 342.015 339.795 457.429 1.00 97.33  ? 176 GLY B N   1 
ATOM 4655 C CA  . GLY D 4 176 ? 342.181 338.465 457.975 1.00 97.33  ? 176 GLY B CA  1 
ATOM 4656 C C   . GLY D 4 176 ? 343.219 337.586 457.309 1.00 97.33  ? 176 GLY B C   1 
ATOM 4657 O O   . GLY D 4 176 ? 343.691 336.638 457.944 1.00 97.33  ? 176 GLY B O   1 
ATOM 4658 N N   . MET D 4 177 ? 343.596 337.852 456.059 1.00 98.25  ? 177 MET B N   1 
ATOM 4659 C CA  . MET D 4 177 ? 344.513 336.990 455.328 1.00 98.25  ? 177 MET B CA  1 
ATOM 4660 C C   . MET D 4 177 ? 345.937 337.507 455.353 1.00 98.25  ? 177 MET B C   1 
ATOM 4661 O O   . MET D 4 177 ? 346.817 336.883 454.754 1.00 98.25  ? 177 MET B O   1 
ATOM 4662 C CB  . MET D 4 177 ? 344.077 336.851 453.872 1.00 98.25  ? 177 MET B CB  1 
ATOM 4663 C CG  . MET D 4 177 ? 342.747 336.203 453.667 1.00 98.25  ? 177 MET B CG  1 
ATOM 4664 S SD  . MET D 4 177 ? 342.410 336.088 451.910 1.00 98.25  ? 177 MET B SD  1 
ATOM 4665 C CE  . MET D 4 177 ? 342.108 337.807 451.531 1.00 98.25  ? 177 MET B CE  1 
ATOM 4666 N N   . GLY D 4 178 ? 346.187 338.629 456.013 1.00 95.47  ? 178 GLY B N   1 
ATOM 4667 C CA  . GLY D 4 178 ? 347.497 339.237 455.937 1.00 95.47  ? 178 GLY B CA  1 
ATOM 4668 C C   . GLY D 4 178 ? 347.785 339.864 454.596 1.00 95.47  ? 178 GLY B C   1 
ATOM 4669 O O   . GLY D 4 178 ? 348.840 339.610 454.014 1.00 95.47  ? 178 GLY B O   1 
ATOM 4670 N N   . VAL D 4 179 ? 346.863 340.662 454.078 1.00 89.43  ? 179 VAL B N   1 
ATOM 4671 C CA  . VAL D 4 179 ? 347.031 341.291 452.782 1.00 89.43  ? 179 VAL B CA  1 
ATOM 4672 C C   . VAL D 4 179 ? 346.551 342.729 452.914 1.00 89.43  ? 179 VAL B C   1 
ATOM 4673 O O   . VAL D 4 179 ? 345.840 343.078 453.855 1.00 89.43  ? 179 VAL B O   1 
ATOM 4674 C CB  . VAL D 4 179 ? 346.259 340.524 451.692 1.00 89.43  ? 179 VAL B CB  1 
ATOM 4675 C CG1 . VAL D 4 179 ? 344.782 340.819 451.756 1.00 89.43  ? 179 VAL B CG1 1 
ATOM 4676 C CG2 . VAL D 4 179 ? 346.824 340.775 450.330 1.00 89.43  ? 179 VAL B CG2 1 
ATOM 4677 N N   . GLY D 4 180 ? 346.996 343.583 451.998 1.00 87.58  ? 180 GLY B N   1 
ATOM 4678 C CA  . GLY D 4 180 ? 346.464 344.929 451.945 1.00 87.58  ? 180 GLY B CA  1 
ATOM 4679 C C   . GLY D 4 180 ? 345.001 344.905 451.546 1.00 87.58  ? 180 GLY B C   1 
ATOM 4680 O O   . GLY D 4 180 ? 344.608 344.232 450.595 1.00 87.58  ? 180 GLY B O   1 
ATOM 4681 N N   . VAL D 4 181 ? 344.181 345.635 452.302 1.00 84.60  ? 181 VAL B N   1 
ATOM 4682 C CA  . VAL D 4 181 ? 342.741 345.576 452.085 1.00 84.60  ? 181 VAL B CA  1 
ATOM 4683 C C   . VAL D 4 181 ? 342.326 346.300 450.810 1.00 84.60  ? 181 VAL B C   1 
ATOM 4684 O O   . VAL D 4 181 ? 341.341 345.907 450.175 1.00 84.60  ? 181 VAL B O   1 
ATOM 4685 C CB  . VAL D 4 181 ? 342.023 346.103 453.341 1.00 84.60  ? 181 VAL B CB  1 
ATOM 4686 C CG1 . VAL D 4 181 ? 342.319 347.563 453.577 1.00 84.60  ? 181 VAL B CG1 1 
ATOM 4687 C CG2 . VAL D 4 181 ? 340.527 345.850 453.277 1.00 84.60  ? 181 VAL B CG2 1 
ATOM 4688 N N   . GLY D 4 182 ? 343.080 347.308 450.377 1.00 86.11  ? 182 GLY B N   1 
ATOM 4689 C CA  . GLY D 4 182 ? 342.739 347.988 449.143 1.00 86.11  ? 182 GLY B CA  1 
ATOM 4690 C C   . GLY D 4 182 ? 343.029 347.165 447.907 1.00 86.11  ? 182 GLY B C   1 
ATOM 4691 O O   . GLY D 4 182 ? 342.400 347.363 446.867 1.00 86.11  ? 182 GLY B O   1 
ATOM 4692 N N   . ASN D 4 183 ? 343.956 346.221 448.004 1.00 84.28  ? 183 ASN B N   1 
ATOM 4693 C CA  . ASN D 4 183 ? 344.366 345.424 446.860 1.00 84.28  ? 183 ASN B CA  1 
ATOM 4694 C C   . ASN D 4 183 ? 343.465 344.234 446.607 1.00 84.28  ? 183 ASN B C   1 
ATOM 4695 O O   . ASN D 4 183 ? 343.835 343.367 445.816 1.00 84.28  ? 183 ASN B O   1 
ATOM 4696 C CB  . ASN D 4 183 ? 345.791 344.925 447.056 1.00 84.28  ? 183 ASN B CB  1 
ATOM 4697 C CG  . ASN D 4 183 ? 346.741 346.032 447.382 1.00 84.28  ? 183 ASN B CG  1 
ATOM 4698 O OD1 . ASN D 4 183 ? 346.760 347.060 446.716 1.00 84.28  ? 183 ASN B OD1 1 
ATOM 4699 N ND2 . ASN D 4 183 ? 347.535 345.841 448.425 1.00 84.28  ? 183 ASN B ND2 1 
ATOM 4700 N N   . LEU D 4 184 ? 342.305 344.156 447.247 1.00 75.63  ? 184 LEU B N   1 
ATOM 4701 C CA  . LEU D 4 184 ? 341.460 342.981 447.115 1.00 75.63  ? 184 LEU B CA  1 
ATOM 4702 C C   . LEU D 4 184 ? 340.682 342.943 445.813 1.00 75.63  ? 184 LEU B C   1 
ATOM 4703 O O   . LEU D 4 184 ? 340.057 341.921 445.520 1.00 75.63  ? 184 LEU B O   1 
ATOM 4704 C CB  . LEU D 4 184 ? 340.483 342.907 448.281 1.00 75.63  ? 184 LEU B CB  1 
ATOM 4705 C CG  . LEU D 4 184 ? 341.012 342.194 449.512 1.00 75.63  ? 184 LEU B CG  1 
ATOM 4706 C CD1 . LEU D 4 184 ? 339.996 342.255 450.623 1.00 75.63  ? 184 LEU B CD1 1 
ATOM 4707 C CD2 . LEU D 4 184 ? 341.324 340.768 449.158 1.00 75.63  ? 184 LEU B CD2 1 
ATOM 4708 N N   . THR D 4 185 ? 340.715 344.004 445.017 1.00 78.22  ? 185 THR B N   1 
ATOM 4709 C CA  . THR D 4 185 ? 339.880 344.082 443.829 1.00 78.22  ? 185 THR B CA  1 
ATOM 4710 C C   . THR D 4 185 ? 340.427 343.301 442.646 1.00 78.22  ? 185 THR B C   1 
ATOM 4711 O O   . THR D 4 185 ? 339.855 343.390 441.557 1.00 78.22  ? 185 THR B O   1 
ATOM 4712 C CB  . THR D 4 185 ? 339.693 345.534 443.422 1.00 78.22  ? 185 THR B CB  1 
ATOM 4713 O OG1 . THR D 4 185 ? 340.969 346.089 443.104 1.00 78.22  ? 185 THR B OG1 1 
ATOM 4714 C CG2 . THR D 4 185 ? 339.093 346.310 444.561 1.00 78.22  ? 185 THR B CG2 1 
ATOM 4715 N N   . ILE D 4 186 ? 341.517 342.560 442.819 1.00 79.98  ? 186 ILE B N   1 
ATOM 4716 C CA  . ILE D 4 186 ? 341.991 341.668 441.771 1.00 79.98  ? 186 ILE B CA  1 
ATOM 4717 C C   . ILE D 4 186 ? 341.036 340.494 441.588 1.00 79.98  ? 186 ILE B C   1 
ATOM 4718 O O   . ILE D 4 186 ? 340.821 340.028 440.464 1.00 79.98  ? 186 ILE B O   1 
ATOM 4719 C CB  . ILE D 4 186 ? 343.421 341.234 442.120 1.00 79.98  ? 186 ILE B CB  1 
ATOM 4720 C CG1 . ILE D 4 186 ? 343.888 340.049 441.288 1.00 79.98  ? 186 ILE B CG1 1 
ATOM 4721 C CG2 . ILE D 4 186 ? 343.520 340.941 443.572 1.00 79.98  ? 186 ILE B CG2 1 
ATOM 4722 C CD1 . ILE D 4 186 ? 345.316 339.677 441.547 1.00 79.98  ? 186 ILE B CD1 1 
ATOM 4723 N N   . PHE D 4 187 ? 340.387 340.060 442.663 1.00 82.38  ? 187 PHE B N   1 
ATOM 4724 C CA  . PHE D 4 187 ? 339.399 338.995 442.616 1.00 82.38  ? 187 PHE B CA  1 
ATOM 4725 C C   . PHE D 4 187 ? 338.124 339.469 441.905 1.00 82.38  ? 187 PHE B C   1 
ATOM 4726 O O   . PHE D 4 187 ? 337.972 340.661 441.630 1.00 82.38  ? 187 PHE B O   1 
ATOM 4727 C CB  . PHE D 4 187 ? 339.110 338.547 444.044 1.00 82.38  ? 187 PHE B CB  1 
ATOM 4728 C CG  . PHE D 4 187 ? 340.238 337.810 444.673 1.00 82.38  ? 187 PHE B CG  1 
ATOM 4729 C CD1 . PHE D 4 187 ? 340.867 336.791 443.996 1.00 82.38  ? 187 PHE B CD1 1 
ATOM 4730 C CD2 . PHE D 4 187 ? 340.681 338.144 445.933 1.00 82.38  ? 187 PHE B CD2 1 
ATOM 4731 C CE1 . PHE D 4 187 ? 341.908 336.113 444.570 1.00 82.38  ? 187 PHE B CE1 1 
ATOM 4732 C CE2 . PHE D 4 187 ? 341.725 337.471 446.508 1.00 82.38  ? 187 PHE B CE2 1 
ATOM 4733 C CZ  . PHE D 4 187 ? 342.337 336.452 445.828 1.00 82.38  ? 187 PHE B CZ  1 
ATOM 4734 N N   . PRO D 4 188 ? 337.197 338.545 441.546 1.00 80.35  ? 188 PRO B N   1 
ATOM 4735 C CA  . PRO D 4 188 ? 335.901 338.994 441.016 1.00 80.35  ? 188 PRO B CA  1 
ATOM 4736 C C   . PRO D 4 188 ? 335.096 339.779 442.031 1.00 80.35  ? 188 PRO B C   1 
ATOM 4737 O O   . PRO D 4 188 ? 334.743 339.265 443.093 1.00 80.35  ? 188 PRO B O   1 
ATOM 4738 C CB  . PRO D 4 188 ? 335.197 337.684 440.648 1.00 80.35  ? 188 PRO B CB  1 
ATOM 4739 C CG  . PRO D 4 188 ? 335.950 336.635 441.361 1.00 80.35  ? 188 PRO B CG  1 
ATOM 4740 C CD  . PRO D 4 188 ? 337.354 337.100 441.333 1.00 80.35  ? 188 PRO B CD  1 
ATOM 4741 N N   . HIS D 4 189 ? 334.801 341.030 441.705 1.00 79.89  ? 189 HIS B N   1 
ATOM 4742 C CA  . HIS D 4 189 ? 334.278 341.986 442.659 1.00 79.89  ? 189 HIS B CA  1 
ATOM 4743 C C   . HIS D 4 189 ? 333.228 342.851 441.990 1.00 79.89  ? 189 HIS B C   1 
ATOM 4744 O O   . HIS D 4 189 ? 332.965 342.730 440.794 1.00 79.89  ? 189 HIS B O   1 
ATOM 4745 C CB  . HIS D 4 189 ? 335.392 342.874 443.202 1.00 79.89  ? 189 HIS B CB  1 
ATOM 4746 C CG  . HIS D 4 189 ? 335.974 343.777 442.168 1.00 79.89  ? 189 HIS B CG  1 
ATOM 4747 N ND1 . HIS D 4 189 ? 336.740 343.312 441.124 1.00 79.89  ? 189 HIS B ND1 1 
ATOM 4748 C CD2 . HIS D 4 189 ? 335.880 345.114 441.999 1.00 79.89  ? 189 HIS B CD2 1 
ATOM 4749 C CE1 . HIS D 4 189 ? 337.106 344.326 440.363 1.00 79.89  ? 189 HIS B CE1 1 
ATOM 4750 N NE2 . HIS D 4 189 ? 336.598 345.432 440.873 1.00 79.89  ? 189 HIS B NE2 1 
ATOM 4751 N N   . GLN D 4 190 ? 332.646 343.751 442.777 1.00 82.28  ? 190 GLN B N   1 
ATOM 4752 C CA  . GLN D 4 190 ? 331.688 344.727 442.279 1.00 82.28  ? 190 GLN B CA  1 
ATOM 4753 C C   . GLN D 4 190 ? 331.566 345.835 443.308 1.00 82.28  ? 190 GLN B C   1 
ATOM 4754 O O   . GLN D 4 190 ? 331.595 345.563 444.509 1.00 82.28  ? 190 GLN B O   1 
ATOM 4755 C CB  . GLN D 4 190 ? 330.321 344.098 442.028 1.00 82.28  ? 190 GLN B CB  1 
ATOM 4756 C CG  . GLN D 4 190 ? 329.386 344.983 441.249 1.00 82.28  ? 190 GLN B CG  1 
ATOM 4757 C CD  . GLN D 4 190 ? 329.593 344.872 439.761 1.00 82.28  ? 190 GLN B CD  1 
ATOM 4758 O OE1 . GLN D 4 190 ? 330.560 345.400 439.215 1.00 82.28  ? 190 GLN B OE1 1 
ATOM 4759 N NE2 . GLN D 4 190 ? 328.679 344.185 439.090 1.00 82.28  ? 190 GLN B NE2 1 
ATOM 4760 N N   . TRP D 4 191 ? 331.438 347.069 442.845 1.00 77.65  ? 191 TRP B N   1 
ATOM 4761 C CA  . TRP D 4 191 ? 331.228 348.194 443.736 1.00 77.65  ? 191 TRP B CA  1 
ATOM 4762 C C   . TRP D 4 191 ? 329.745 348.463 443.891 1.00 77.65  ? 191 TRP B C   1 
ATOM 4763 O O   . TRP D 4 191 ? 328.994 348.442 442.915 1.00 77.65  ? 191 TRP B O   1 
ATOM 4764 C CB  . TRP D 4 191 ? 331.911 349.444 443.198 1.00 77.65  ? 191 TRP B CB  1 
ATOM 4765 C CG  . TRP D 4 191 ? 333.368 349.346 443.193 1.00 77.65  ? 191 TRP B CG  1 
ATOM 4766 C CD1 . TRP D 4 191 ? 334.167 349.116 442.121 1.00 77.65  ? 191 TRP B CD1 1 
ATOM 4767 C CD2 . TRP D 4 191 ? 334.226 349.472 444.318 1.00 77.65  ? 191 TRP B CD2 1 
ATOM 4768 N NE1 . TRP D 4 191 ? 335.479 349.091 442.510 1.00 77.65  ? 191 TRP B NE1 1 
ATOM 4769 C CE2 . TRP D 4 191 ? 335.540 349.309 443.859 1.00 77.65  ? 191 TRP B CE2 1 
ATOM 4770 C CE3 . TRP D 4 191 ? 334.012 349.709 445.670 1.00 77.65  ? 191 TRP B CE3 1 
ATOM 4771 C CZ2 . TRP D 4 191 ? 336.631 349.370 444.705 1.00 77.65  ? 191 TRP B CZ2 1 
ATOM 4772 C CZ3 . TRP D 4 191 ? 335.094 349.774 446.505 1.00 77.65  ? 191 TRP B CZ3 1 
ATOM 4773 C CH2 . TRP D 4 191 ? 336.388 349.606 446.024 1.00 77.65  ? 191 TRP B CH2 1 
ATOM 4774 N N   . ILE D 4 192 ? 329.327 348.724 445.120 1.00 78.77  ? 192 ILE B N   1 
ATOM 4775 C CA  . ILE D 4 192 ? 327.992 349.225 445.399 1.00 78.77  ? 192 ILE B CA  1 
ATOM 4776 C C   . ILE D 4 192 ? 328.155 350.658 445.861 1.00 78.77  ? 192 ILE B C   1 
ATOM 4777 O O   . ILE D 4 192 ? 328.655 350.914 446.962 1.00 78.77  ? 192 ILE B O   1 
ATOM 4778 C CB  . ILE D 4 192 ? 327.262 348.388 446.448 1.00 78.77  ? 192 ILE B CB  1 
ATOM 4779 C CG1 . ILE D 4 192 ? 327.104 346.962 445.952 1.00 78.77  ? 192 ILE B CG1 1 
ATOM 4780 C CG2 . ILE D 4 192 ? 325.912 348.981 446.716 1.00 78.77  ? 192 ILE B CG2 1 
ATOM 4781 C CD1 . ILE D 4 192 ? 326.459 346.061 446.945 1.00 78.77  ? 192 ILE B CD1 1 
ATOM 4782 N N   . ASN D 4 193 ? 327.754 351.593 445.017 1.00 85.84  ? 193 ASN B N   1 
ATOM 4783 C CA  . ASN D 4 193 ? 327.890 353.012 445.292 1.00 85.84  ? 193 ASN B CA  1 
ATOM 4784 C C   . ASN D 4 193 ? 326.499 353.588 445.477 1.00 85.84  ? 193 ASN B C   1 
ATOM 4785 O O   . ASN D 4 193 ? 325.787 353.812 444.494 1.00 85.84  ? 193 ASN B O   1 
ATOM 4786 C CB  . ASN D 4 193 ? 328.622 353.712 444.154 1.00 85.84  ? 193 ASN B CB  1 
ATOM 4787 C CG  . ASN D 4 193 ? 329.299 354.965 444.601 1.00 85.84  ? 193 ASN B CG  1 
ATOM 4788 O OD1 . ASN D 4 193 ? 329.031 355.469 445.686 1.00 85.84  ? 193 ASN B OD1 1 
ATOM 4789 N ND2 . ASN D 4 193 ? 330.205 355.472 443.780 1.00 85.84  ? 193 ASN B ND2 1 
ATOM 4790 N N   . LEU D 4 194 ? 326.128 353.851 446.731 1.00 84.43  ? 194 LEU B N   1 
ATOM 4791 C CA  . LEU D 4 194 ? 324.757 354.197 447.090 1.00 84.43  ? 194 LEU B CA  1 
ATOM 4792 C C   . LEU D 4 194 ? 324.291 355.523 446.521 1.00 84.43  ? 194 LEU B C   1 
ATOM 4793 O O   . LEU D 4 194 ? 323.092 355.805 446.569 1.00 84.43  ? 194 LEU B O   1 
ATOM 4794 C CB  . LEU D 4 194 ? 324.607 354.229 448.603 1.00 84.43  ? 194 LEU B CB  1 
ATOM 4795 C CG  . LEU D 4 194 ? 324.385 352.869 449.241 1.00 84.43  ? 194 LEU B CG  1 
ATOM 4796 C CD1 . LEU D 4 194 ? 324.231 353.015 450.726 1.00 84.43  ? 194 LEU B CD1 1 
ATOM 4797 C CD2 . LEU D 4 194 ? 323.148 352.265 448.654 1.00 84.43  ? 194 LEU B CD2 1 
ATOM 4798 N N   . ARG D 4 195 ? 325.200 356.344 446.007 1.00 91.04  ? 195 ARG B N   1 
ATOM 4799 C CA  . ARG D 4 195 ? 324.791 357.546 445.301 1.00 91.04  ? 195 ARG B CA  1 
ATOM 4800 C C   . ARG D 4 195 ? 324.086 357.207 443.994 1.00 91.04  ? 195 ARG B C   1 
ATOM 4801 O O   . ARG D 4 195 ? 323.019 357.756 443.699 1.00 91.04  ? 195 ARG B O   1 
ATOM 4802 C CB  . ARG D 4 195 ? 326.014 358.419 445.054 1.00 91.04  ? 195 ARG B CB  1 
ATOM 4803 C CG  . ARG D 4 195 ? 325.800 359.564 444.117 1.00 91.04  ? 195 ARG B CG  1 
ATOM 4804 C CD  . ARG D 4 195 ? 327.133 360.051 443.614 1.00 91.04  ? 195 ARG B CD  1 
ATOM 4805 N NE  . ARG D 4 195 ? 326.988 361.238 442.792 1.00 91.04  ? 195 ARG B NE  1 
ATOM 4806 C CZ  . ARG D 4 195 ? 326.975 362.470 443.276 1.00 91.04  ? 195 ARG B CZ  1 
ATOM 4807 N NH1 . ARG D 4 195 ? 327.103 362.668 444.578 1.00 91.04  ? 195 ARG B NH1 1 
ATOM 4808 N NH2 . ARG D 4 195 ? 326.836 363.501 442.460 1.00 91.04  ? 195 ARG B NH2 1 
ATOM 4809 N N   . THR D 4 196 ? 324.659 356.303 443.197 1.00 93.95  ? 196 THR B N   1 
ATOM 4810 C CA  . THR D 4 196 ? 324.087 355.920 441.912 1.00 93.95  ? 196 THR B CA  1 
ATOM 4811 C C   . THR D 4 196 ? 323.683 354.460 441.813 1.00 93.95  ? 196 THR B C   1 
ATOM 4812 O O   . THR D 4 196 ? 322.530 354.176 441.492 1.00 93.95  ? 196 THR B O   1 
ATOM 4813 C CB  . THR D 4 196 ? 325.075 356.191 440.771 1.00 93.95  ? 196 THR B CB  1 
ATOM 4814 O OG1 . THR D 4 196 ? 326.024 355.119 440.708 1.00 93.95  ? 196 THR B OG1 1 
ATOM 4815 C CG2 . THR D 4 196 ? 325.806 357.505 440.974 1.00 93.95  ? 196 THR B CG2 1 
ATOM 4816 N N   . ASN D 4 197 ? 324.592 353.533 442.072 1.00 91.82  ? 197 ASN B N   1 
ATOM 4817 C CA  . ASN D 4 197 ? 324.355 352.108 441.916 1.00 91.82  ? 197 ASN B CA  1 
ATOM 4818 C C   . ASN D 4 197 ? 323.494 351.609 443.065 1.00 91.82  ? 197 ASN B C   1 
ATOM 4819 O O   . ASN D 4 197 ? 323.369 352.261 444.101 1.00 91.82  ? 197 ASN B O   1 
ATOM 4820 C CB  . ASN D 4 197 ? 325.686 351.355 441.870 1.00 91.82  ? 197 ASN B CB  1 
ATOM 4821 C CG  . ASN D 4 197 ? 325.550 349.967 441.310 1.00 91.82  ? 197 ASN B CG  1 
ATOM 4822 O OD1 . ASN D 4 197 ? 324.459 349.546 440.935 1.00 91.82  ? 197 ASN B OD1 1 
ATOM 4823 N ND2 . ASN D 4 197 ? 326.659 349.243 441.244 1.00 91.82  ? 197 ASN B ND2 1 
ATOM 4824 N N   . ASN D 4 198 ? 322.870 350.452 442.871 1.00 89.18  ? 198 ASN B N   1 
ATOM 4825 C CA  . ASN D 4 198 ? 322.044 349.916 443.945 1.00 89.18  ? 198 ASN B CA  1 
ATOM 4826 C C   . ASN D 4 198 ? 322.258 348.437 444.237 1.00 89.18  ? 198 ASN B C   1 
ATOM 4827 O O   . ASN D 4 198 ? 322.079 348.031 445.388 1.00 89.18  ? 198 ASN B O   1 
ATOM 4828 C CB  . ASN D 4 198 ? 320.570 350.143 443.625 1.00 89.18  ? 198 ASN B CB  1 
ATOM 4829 C CG  . ASN D 4 198 ? 319.717 350.155 444.854 1.00 89.18  ? 198 ASN B CG  1 
ATOM 4830 O OD1 . ASN D 4 198 ? 320.225 350.118 445.963 1.00 89.18  ? 198 ASN B OD1 1 
ATOM 4831 N ND2 . ASN D 4 198 ? 318.406 350.199 444.669 1.00 89.18  ? 198 ASN B ND2 1 
ATOM 4832 N N   . SER D 4 199 ? 322.641 347.613 443.266 1.00 89.35  ? 199 SER B N   1 
ATOM 4833 C CA  . SER D 4 199 ? 322.726 346.177 443.478 1.00 89.35  ? 199 SER B CA  1 
ATOM 4834 C C   . SER D 4 199 ? 323.949 345.615 442.780 1.00 89.35  ? 199 SER B C   1 
ATOM 4835 O O   . SER D 4 199 ? 324.545 346.257 441.917 1.00 89.35  ? 199 SER B O   1 
ATOM 4836 C CB  . SER D 4 199 ? 321.490 345.453 442.962 1.00 89.35  ? 199 SER B CB  1 
ATOM 4837 O OG  . SER D 4 199 ? 321.661 344.056 443.099 1.00 89.35  ? 199 SER B OG  1 
ATOM 4838 N N   . ALA D 4 200 ? 324.298 344.388 443.149 1.00 89.70  ? 200 ALA B N   1 
ATOM 4839 C CA  . ALA D 4 200 ? 325.455 343.711 442.588 1.00 89.70  ? 200 ALA B CA  1 
ATOM 4840 C C   . ALA D 4 200 ? 325.121 342.249 442.353 1.00 89.70  ? 200 ALA B C   1 
ATOM 4841 O O   . ALA D 4 200 ? 324.292 341.667 443.054 1.00 89.70  ? 200 ALA B O   1 
ATOM 4842 C CB  . ALA D 4 200 ? 326.670 343.818 443.508 1.00 89.70  ? 200 ALA B CB  1 
ATOM 4843 N N   . THR D 4 201 ? 325.778 341.657 441.363 1.00 94.31  ? 201 THR B N   1 
ATOM 4844 C CA  . THR D 4 201 ? 325.534 340.271 440.999 1.00 94.31  ? 201 THR B CA  1 
ATOM 4845 C C   . THR D 4 201 ? 326.856 339.618 440.639 1.00 94.31  ? 201 THR B C   1 
ATOM 4846 O O   . THR D 4 201 ? 327.672 340.217 439.936 1.00 94.31  ? 201 THR B O   1 
ATOM 4847 C CB  . THR D 4 201 ? 324.559 340.174 439.823 1.00 94.31  ? 201 THR B CB  1 
ATOM 4848 O OG1 . THR D 4 201 ? 323.417 340.997 440.080 1.00 94.31  ? 201 THR B OG1 1 
ATOM 4849 C CG2 . THR D 4 201 ? 324.097 338.748 439.621 1.00 94.31  ? 201 THR B CG2 1 
ATOM 4850 N N   . LEU D 4 202 ? 327.072 338.402 441.122 1.00 91.38  ? 202 LEU B N   1 
ATOM 4851 C CA  . LEU D 4 202 ? 328.267 337.643 440.802 1.00 91.38  ? 202 LEU B CA  1 
ATOM 4852 C C   . LEU D 4 202 ? 327.871 336.284 440.259 1.00 91.38  ? 202 LEU B C   1 
ATOM 4853 O O   . LEU D 4 202 ? 326.822 335.743 440.607 1.00 91.38  ? 202 LEU B O   1 
ATOM 4854 C CB  . LEU D 4 202 ? 329.142 337.456 442.019 1.00 91.38  ? 202 LEU B CB  1 
ATOM 4855 C CG  . LEU D 4 202 ? 329.722 338.739 442.578 1.00 91.38  ? 202 LEU B CG  1 
ATOM 4856 C CD1 . LEU D 4 202 ? 330.027 338.542 444.037 1.00 91.38  ? 202 LEU B CD1 1 
ATOM 4857 C CD2 . LEU D 4 202 ? 330.971 339.094 441.813 1.00 91.38  ? 202 LEU B CD2 1 
ATOM 4858 N N   . VAL D 4 203 ? 328.715 335.740 439.393 1.00 95.36  ? 203 VAL B N   1 
ATOM 4859 C CA  . VAL D 4 203 ? 328.552 334.390 438.876 1.00 95.36  ? 203 VAL B CA  1 
ATOM 4860 C C   . VAL D 4 203 ? 329.890 333.690 439.027 1.00 95.36  ? 203 VAL B C   1 
ATOM 4861 O O   . VAL D 4 203 ? 330.872 334.093 438.398 1.00 95.36  ? 203 VAL B O   1 
ATOM 4862 C CB  . VAL D 4 203 ? 328.105 334.377 437.409 1.00 95.36  ? 203 VAL B CB  1 
ATOM 4863 C CG1 . VAL D 4 203 ? 328.094 332.976 436.903 1.00 95.36  ? 203 VAL B CG1 1 
ATOM 4864 C CG2 . VAL D 4 203 ? 326.730 334.971 437.259 1.00 95.36  ? 203 VAL B CG2 1 
ATOM 4865 N N   . MET D 4 204 ? 329.937 332.650 439.848 1.00 97.87  ? 204 MET B N   1 
ATOM 4866 C CA  . MET D 4 204 ? 331.202 332.032 440.178 1.00 97.87  ? 204 MET B CA  1 
ATOM 4867 C C   . MET D 4 204 ? 331.225 330.579 439.738 1.00 97.87  ? 204 MET B C   1 
ATOM 4868 O O   . MET D 4 204 ? 330.326 329.812 440.104 1.00 97.87  ? 204 MET B O   1 
ATOM 4869 C CB  . MET D 4 204 ? 331.459 332.117 441.670 1.00 97.87  ? 204 MET B CB  1 
ATOM 4870 C CG  . MET D 4 204 ? 331.703 333.515 442.130 1.00 97.87  ? 204 MET B CG  1 
ATOM 4871 S SD  . MET D 4 204 ? 333.205 334.173 441.402 1.00 97.87  ? 204 MET B SD  1 
ATOM 4872 C CE  . MET D 4 204 ? 334.439 333.175 442.226 1.00 97.87  ? 204 MET B CE  1 
ATOM 4873 N N   . PRO D 4 205 ? 332.218 330.161 438.972 1.00 98.98  ? 205 PRO B N   1 
ATOM 4874 C CA  . PRO D 4 205 ? 332.353 328.751 438.613 1.00 98.98  ? 205 PRO B CA  1 
ATOM 4875 C C   . PRO D 4 205 ? 333.058 327.986 439.726 1.00 98.98  ? 205 PRO B C   1 
ATOM 4876 O O   . PRO D 4 205 ? 333.536 328.556 440.700 1.00 98.98  ? 205 PRO B O   1 
ATOM 4877 C CB  . PRO D 4 205 ? 333.197 328.804 437.346 1.00 98.98  ? 205 PRO B CB  1 
ATOM 4878 C CG  . PRO D 4 205 ? 334.042 329.998 437.538 1.00 98.98  ? 205 PRO B CG  1 
ATOM 4879 C CD  . PRO D 4 205 ? 333.217 330.997 438.290 1.00 98.98  ? 205 PRO B CD  1 
ATOM 4880 N N   . TYR D 4 206 ? 333.122 326.672 439.558 1.00 107.64 ? 206 TYR B N   1 
ATOM 4881 C CA  . TYR D 4 206 ? 333.732 325.792 440.545 1.00 107.64 ? 206 TYR B CA  1 
ATOM 4882 C C   . TYR D 4 206 ? 335.242 325.811 440.364 1.00 107.64 ? 206 TYR B C   1 
ATOM 4883 O O   . TYR D 4 206 ? 335.763 325.230 439.407 1.00 107.64 ? 206 TYR B O   1 
ATOM 4884 C CB  . TYR D 4 206 ? 333.197 324.372 440.396 1.00 107.64 ? 206 TYR B CB  1 
ATOM 4885 C CG  . TYR D 4 206 ? 333.936 323.357 441.216 1.00 107.64 ? 206 TYR B CG  1 
ATOM 4886 C CD1 . TYR D 4 206 ? 333.839 323.355 442.597 1.00 107.64 ? 206 TYR B CD1 1 
ATOM 4887 C CD2 . TYR D 4 206 ? 334.728 322.397 440.610 1.00 107.64 ? 206 TYR B CD2 1 
ATOM 4888 C CE1 . TYR D 4 206 ? 334.514 322.424 443.354 1.00 107.64 ? 206 TYR B CE1 1 
ATOM 4889 C CE2 . TYR D 4 206 ? 335.406 321.463 441.357 1.00 107.64 ? 206 TYR B CE2 1 
ATOM 4890 C CZ  . TYR D 4 206 ? 335.293 321.480 442.727 1.00 107.64 ? 206 TYR B CZ  1 
ATOM 4891 O OH  . TYR D 4 206 ? 335.971 320.552 443.478 1.00 107.64 ? 206 TYR B OH  1 
ATOM 4892 N N   . ILE D 4 207 ? 335.943 326.464 441.283 1.00 103.63 ? 207 ILE B N   1 
ATOM 4893 C CA  . ILE D 4 207 ? 337.378 326.684 441.165 1.00 103.63 ? 207 ILE B CA  1 
ATOM 4894 C C   . ILE D 4 207 ? 338.067 325.821 442.209 1.00 103.63 ? 207 ILE B C   1 
ATOM 4895 O O   . ILE D 4 207 ? 338.200 326.224 443.369 1.00 103.63 ? 207 ILE B O   1 
ATOM 4896 C CB  . ILE D 4 207 ? 337.750 328.155 441.341 1.00 103.63 ? 207 ILE B CB  1 
ATOM 4897 C CG1 . ILE D 4 207 ? 336.849 329.027 440.481 1.00 103.63 ? 207 ILE B CG1 1 
ATOM 4898 C CG2 . ILE D 4 207 ? 339.184 328.372 440.955 1.00 103.63 ? 207 ILE B CG2 1 
ATOM 4899 C CD1 . ILE D 4 207 ? 337.036 330.495 440.725 1.00 103.63 ? 207 ILE B CD1 1 
ATOM 4900 N N   . ASN D 4 208 ? 338.521 324.641 441.803 1.00 105.18 ? 208 ASN B N   1 
ATOM 4901 C CA  . ASN D 4 208 ? 339.266 323.775 442.702 1.00 105.18 ? 208 ASN B CA  1 
ATOM 4902 C C   . ASN D 4 208 ? 340.153 322.862 441.876 1.00 105.18 ? 208 ASN B C   1 
ATOM 4903 O O   . ASN D 4 208 ? 339.929 322.658 440.682 1.00 105.18 ? 208 ASN B O   1 
ATOM 4904 C CB  . ASN D 4 208 ? 338.339 322.954 443.597 1.00 105.18 ? 208 ASN B CB  1 
ATOM 4905 C CG  . ASN D 4 208 ? 339.024 322.471 444.853 1.00 105.18 ? 208 ASN B CG  1 
ATOM 4906 O OD1 . ASN D 4 208 ? 340.246 322.545 444.973 1.00 105.18 ? 208 ASN B OD1 1 
ATOM 4907 N ND2 . ASN D 4 208 ? 338.243 321.963 445.796 1.00 105.18 ? 208 ASN B ND2 1 
ATOM 4908 N N   . SER D 4 209 ? 341.171 322.318 442.538 1.00 106.11 ? 209 SER B N   1 
ATOM 4909 C CA  . SER D 4 209 ? 342.115 321.442 441.861 1.00 106.11 ? 209 SER B CA  1 
ATOM 4910 C C   . SER D 4 209 ? 341.501 320.079 441.583 1.00 106.11 ? 209 SER B C   1 
ATOM 4911 O O   . SER D 4 209 ? 341.349 319.679 440.426 1.00 106.11 ? 209 SER B O   1 
ATOM 4912 C CB  . SER D 4 209 ? 343.366 321.302 442.715 1.00 106.11 ? 209 SER B CB  1 
ATOM 4913 O OG  . SER D 4 209 ? 343.003 321.147 444.072 1.00 106.11 ? 209 SER B OG  1 
ATOM 4914 N N   . VAL D 4 210 ? 341.143 319.355 442.634 1.00 115.79 ? 210 VAL B N   1 
ATOM 4915 C CA  . VAL D 4 210 ? 340.496 318.053 442.518 1.00 115.79 ? 210 VAL B CA  1 
ATOM 4916 C C   . VAL D 4 210 ? 339.083 318.251 441.976 1.00 115.79 ? 210 VAL B C   1 
ATOM 4917 O O   . VAL D 4 210 ? 338.370 319.157 442.429 1.00 115.79 ? 210 VAL B O   1 
ATOM 4918 C CB  . VAL D 4 210 ? 340.543 317.321 443.871 1.00 115.79 ? 210 VAL B CB  1 
ATOM 4919 C CG1 . VAL D 4 210 ? 340.102 318.233 444.998 1.00 115.79 ? 210 VAL B CG1 1 
ATOM 4920 C CG2 . VAL D 4 210 ? 339.681 316.070 443.861 1.00 115.79 ? 210 VAL B CG2 1 
ATOM 4921 N N   . PRO D 4 211 ? 338.658 317.482 440.968 1.00 119.24 ? 211 PRO B N   1 
ATOM 4922 C CA  . PRO D 4 211 ? 337.331 317.703 440.376 1.00 119.24 ? 211 PRO B CA  1 
ATOM 4923 C C   . PRO D 4 211 ? 336.170 317.345 441.281 1.00 119.24 ? 211 PRO B C   1 
ATOM 4924 O O   . PRO D 4 211 ? 335.133 318.016 441.215 1.00 119.24 ? 211 PRO B O   1 
ATOM 4925 C CB  . PRO D 4 211 ? 337.344 316.793 439.144 1.00 119.24 ? 211 PRO B CB  1 
ATOM 4926 C CG  . PRO D 4 211 ? 338.347 315.758 439.455 1.00 119.24 ? 211 PRO B CG  1 
ATOM 4927 C CD  . PRO D 4 211 ? 339.411 316.449 440.243 1.00 119.24 ? 211 PRO B CD  1 
ATOM 4928 N N   . MET D 4 212 ? 336.301 316.324 442.121 1.00 132.54 ? 212 MET B N   1 
ATOM 4929 C CA  . MET D 4 212 ? 335.233 315.970 443.046 1.00 132.54 ? 212 MET B CA  1 
ATOM 4930 C C   . MET D 4 212 ? 335.830 315.895 444.437 1.00 132.54 ? 212 MET B C   1 
ATOM 4931 O O   . MET D 4 212 ? 336.587 314.970 444.741 1.00 132.54 ? 212 MET B O   1 
ATOM 4932 C CB  . MET D 4 212 ? 334.574 314.645 442.670 1.00 132.54 ? 212 MET B CB  1 
ATOM 4933 C CG  . MET D 4 212 ? 333.805 314.688 441.369 1.00 132.54 ? 212 MET B CG  1 
ATOM 4934 S SD  . MET D 4 212 ? 332.661 313.309 441.232 1.00 132.54 ? 212 MET B SD  1 
ATOM 4935 C CE  . MET D 4 212 ? 331.368 313.876 442.331 1.00 132.54 ? 212 MET B CE  1 
ATOM 4936 N N   . ASP D 4 213 ? 335.488 316.865 445.270 1.00 128.96 ? 213 ASP B N   1 
ATOM 4937 C CA  . ASP D 4 213 ? 336.114 317.045 446.564 1.00 128.96 ? 213 ASP B CA  1 
ATOM 4938 C C   . ASP D 4 213 ? 335.056 316.887 447.646 1.00 128.96 ? 213 ASP B C   1 
ATOM 4939 O O   . ASP D 4 213 ? 333.857 317.017 447.389 1.00 128.96 ? 213 ASP B O   1 
ATOM 4940 C CB  . ASP D 4 213 ? 336.794 318.421 446.621 1.00 128.96 ? 213 ASP B CB  1 
ATOM 4941 C CG  . ASP D 4 213 ? 337.517 318.675 447.921 1.00 128.96 ? 213 ASP B CG  1 
ATOM 4942 O OD1 . ASP D 4 213 ? 338.202 317.753 448.410 1.00 128.96 ? 213 ASP B OD1 1 
ATOM 4943 O OD2 . ASP D 4 213 ? 337.410 319.797 448.447 1.00 128.96 ? 213 ASP B OD2 1 
ATOM 4944 N N   . ASN D 4 214 ? 335.512 316.567 448.854 1.00 130.36 ? 214 ASN B N   1 
ATOM 4945 C CA  . ASN D 4 214 ? 334.651 316.568 450.023 1.00 130.36 ? 214 ASN B CA  1 
ATOM 4946 C C   . ASN D 4 214 ? 334.089 317.960 450.268 1.00 130.36 ? 214 ASN B C   1 
ATOM 4947 O O   . ASN D 4 214 ? 334.760 318.972 450.061 1.00 130.36 ? 214 ASN B O   1 
ATOM 4948 C CB  . ASN D 4 214 ? 335.429 316.111 451.248 1.00 130.36 ? 214 ASN B CB  1 
ATOM 4949 C CG  . ASN D 4 214 ? 334.529 315.680 452.369 1.00 130.36 ? 214 ASN B CG  1 
ATOM 4950 O OD1 . ASN D 4 214 ? 333.853 316.499 452.991 1.00 130.36 ? 214 ASN B OD1 1 
ATOM 4951 N ND2 . ASN D 4 214 ? 334.512 314.385 452.641 1.00 130.36 ? 214 ASN B ND2 1 
ATOM 4952 N N   . MET D 4 215 ? 332.837 318.004 450.710 1.00 129.08 ? 215 MET B N   1 
ATOM 4953 C CA  . MET D 4 215 ? 332.148 319.262 450.938 1.00 129.08 ? 215 MET B CA  1 
ATOM 4954 C C   . MET D 4 215 ? 332.085 319.644 452.406 1.00 129.08 ? 215 MET B C   1 
ATOM 4955 O O   . MET D 4 215 ? 331.584 320.725 452.725 1.00 129.08 ? 215 MET B O   1 
ATOM 4956 C CB  . MET D 4 215 ? 330.727 319.199 450.373 1.00 129.08 ? 215 MET B CB  1 
ATOM 4957 C CG  . MET D 4 215 ? 330.655 318.868 448.901 1.00 129.08 ? 215 MET B CG  1 
ATOM 4958 S SD  . MET D 4 215 ? 328.950 318.766 448.326 1.00 129.08 ? 215 MET B SD  1 
ATOM 4959 C CE  . MET D 4 215 ? 328.526 320.499 448.196 1.00 129.08 ? 215 MET B CE  1 
ATOM 4960 N N   . PHE D 4 216 ? 332.576 318.800 453.305 1.00 118.41 ? 216 PHE B N   1 
ATOM 4961 C CA  . PHE D 4 216 ? 332.505 319.077 454.732 1.00 118.41 ? 216 PHE B CA  1 
ATOM 4962 C C   . PHE D 4 216 ? 333.807 319.596 455.306 1.00 118.41 ? 216 PHE B C   1 
ATOM 4963 O O   . PHE D 4 216 ? 333.790 320.437 456.205 1.00 118.41 ? 216 PHE B O   1 
ATOM 4964 C CB  . PHE D 4 216 ? 332.089 317.817 455.488 1.00 118.41 ? 216 PHE B CB  1 
ATOM 4965 C CG  . PHE D 4 216 ? 330.615 317.695 455.670 1.00 118.41 ? 216 PHE B CG  1 
ATOM 4966 C CD1 . PHE D 4 216 ? 329.985 318.314 456.734 1.00 118.41 ? 216 PHE B CD1 1 
ATOM 4967 C CD2 . PHE D 4 216 ? 329.854 316.981 454.766 1.00 118.41 ? 216 PHE B CD2 1 
ATOM 4968 C CE1 . PHE D 4 216 ? 328.618 318.211 456.903 1.00 118.41 ? 216 PHE B CE1 1 
ATOM 4969 C CE2 . PHE D 4 216 ? 328.489 316.876 454.929 1.00 118.41 ? 216 PHE B CE2 1 
ATOM 4970 C CZ  . PHE D 4 216 ? 327.870 317.491 455.998 1.00 118.41 ? 216 PHE B CZ  1 
ATOM 4971 N N   . ARG D 4 217 ? 334.934 319.112 454.806 1.00 105.16 ? 217 ARG B N   1 
ATOM 4972 C CA  . ARG D 4 217 ? 336.227 319.580 455.263 1.00 105.16 ? 217 ARG B CA  1 
ATOM 4973 C C   . ARG D 4 217 ? 336.817 320.641 454.351 1.00 105.16 ? 217 ARG B C   1 
ATOM 4974 O O   . ARG D 4 217 ? 338.028 320.867 454.396 1.00 105.16 ? 217 ARG B O   1 
ATOM 4975 C CB  . ARG D 4 217 ? 337.186 318.398 455.377 1.00 105.16 ? 217 ARG B CB  1 
ATOM 4976 C CG  . ARG D 4 217 ? 336.682 317.288 456.282 1.00 105.16 ? 217 ARG B CG  1 
ATOM 4977 C CD  . ARG D 4 217 ? 337.811 316.369 456.705 1.00 105.16 ? 217 ARG B CD  1 
ATOM 4978 N NE  . ARG D 4 217 ? 337.682 315.933 458.089 1.00 105.16 ? 217 ARG B NE  1 
ATOM 4979 C CZ  . ARG D 4 217 ? 338.654 315.345 458.774 1.00 105.16 ? 217 ARG B CZ  1 
ATOM 4980 N NH1 . ARG D 4 217 ? 338.459 314.980 460.031 1.00 105.16 ? 217 ARG B NH1 1 
ATOM 4981 N NH2 . ARG D 4 217 ? 339.827 315.126 458.200 1.00 105.16 ? 217 ARG B NH2 1 
ATOM 4982 N N   . HIS D 4 218 ? 335.999 321.289 453.527 1.00 101.73 ? 218 HIS B N   1 
ATOM 4983 C CA  . HIS D 4 218 ? 336.482 322.238 452.538 1.00 101.73 ? 218 HIS B CA  1 
ATOM 4984 C C   . HIS D 4 218 ? 335.520 323.409 452.432 1.00 101.73 ? 218 HIS B C   1 
ATOM 4985 O O   . HIS D 4 218 ? 334.303 323.226 452.455 1.00 101.73 ? 218 HIS B O   1 
ATOM 4986 C CB  . HIS D 4 218 ? 336.628 321.561 451.181 1.00 101.73 ? 218 HIS B CB  1 
ATOM 4987 C CG  . HIS D 4 218 ? 337.577 322.248 450.254 1.00 101.73 ? 218 HIS B CG  1 
ATOM 4988 N ND1 . HIS D 4 218 ? 338.603 321.579 449.624 1.00 101.73 ? 218 HIS B ND1 1 
ATOM 4989 C CD2 . HIS D 4 218 ? 337.635 323.525 449.815 1.00 101.73 ? 218 HIS B CD2 1 
ATOM 4990 C CE1 . HIS D 4 218 ? 339.266 322.421 448.854 1.00 101.73 ? 218 HIS B CE1 1 
ATOM 4991 N NE2 . HIS D 4 218 ? 338.701 323.609 448.953 1.00 101.73 ? 218 HIS B NE2 1 
ATOM 4992 N N   . ASN D 4 219 ? 336.074 324.612 452.316 1.00 99.84  ? 219 ASN B N   1 
ATOM 4993 C CA  . ASN D 4 219 ? 335.303 325.831 452.087 1.00 99.84  ? 219 ASN B CA  1 
ATOM 4994 C C   . ASN D 4 219 ? 335.941 326.532 450.896 1.00 99.84  ? 219 ASN B C   1 
ATOM 4995 O O   . ASN D 4 219 ? 336.860 327.336 451.060 1.00 99.84  ? 219 ASN B O   1 
ATOM 4996 C CB  . ASN D 4 219 ? 335.296 326.707 453.321 1.00 99.84  ? 219 ASN B CB  1 
ATOM 4997 C CG  . ASN D 4 219 ? 334.485 326.115 454.434 1.00 99.84  ? 219 ASN B CG  1 
ATOM 4998 O OD1 . ASN D 4 219 ? 333.456 325.490 454.193 1.00 99.84  ? 219 ASN B OD1 1 
ATOM 4999 N ND2 . ASN D 4 219 ? 334.945 326.291 455.664 1.00 99.84  ? 219 ASN B ND2 1 
ATOM 5000 N N   . ASN D 4 220 ? 335.445 326.240 449.699 1.00 90.98  ? 220 ASN B N   1 
ATOM 5001 C CA  . ASN D 4 220 ? 336.128 326.671 448.490 1.00 90.98  ? 220 ASN B CA  1 
ATOM 5002 C C   . ASN D 4 220 ? 335.842 328.113 448.094 1.00 90.98  ? 220 ASN B C   1 
ATOM 5003 O O   . ASN D 4 220 ? 336.442 328.592 447.129 1.00 90.98  ? 220 ASN B O   1 
ATOM 5004 C CB  . ASN D 4 220 ? 335.782 325.726 447.340 1.00 90.98  ? 220 ASN B CB  1 
ATOM 5005 C CG  . ASN D 4 220 ? 334.293 325.533 447.169 1.00 90.98  ? 220 ASN B CG  1 
ATOM 5006 O OD1 . ASN D 4 220 ? 333.488 326.164 447.848 1.00 90.98  ? 220 ASN B OD1 1 
ATOM 5007 N ND2 . ASN D 4 220 ? 333.917 324.639 446.267 1.00 90.98  ? 220 ASN B ND2 1 
ATOM 5008 N N   . LEU D 4 221 ? 334.962 328.817 448.796 1.00 87.43  ? 221 LEU B N   1 
ATOM 5009 C CA  . LEU D 4 221 ? 334.696 330.216 448.499 1.00 87.43  ? 221 LEU B CA  1 
ATOM 5010 C C   . LEU D 4 221 ? 334.464 330.980 449.790 1.00 87.43  ? 221 LEU B C   1 
ATOM 5011 O O   . LEU D 4 221 ? 334.353 330.398 450.870 1.00 87.43  ? 221 LEU B O   1 
ATOM 5012 C CB  . LEU D 4 221 ? 333.490 330.380 447.570 1.00 87.43  ? 221 LEU B CB  1 
ATOM 5013 C CG  . LEU D 4 221 ? 333.799 330.291 446.079 1.00 87.43  ? 221 LEU B CG  1 
ATOM 5014 C CD1 . LEU D 4 221 ? 332.579 330.573 445.245 1.00 87.43  ? 221 LEU B CD1 1 
ATOM 5015 C CD2 . LEU D 4 221 ? 334.899 331.252 445.724 1.00 87.43  ? 221 LEU B CD2 1 
ATOM 5016 N N   . THR D 4 222 ? 334.393 332.302 449.663 1.00 86.00  ? 222 THR B N   1 
ATOM 5017 C CA  . THR D 4 222 ? 334.121 333.187 450.793 1.00 86.00  ? 222 THR B CA  1 
ATOM 5018 C C   . THR D 4 222 ? 333.594 334.496 450.238 1.00 86.00  ? 222 THR B C   1 
ATOM 5019 O O   . THR D 4 222 ? 334.271 335.137 449.431 1.00 86.00  ? 222 THR B O   1 
ATOM 5020 C CB  . THR D 4 222 ? 335.373 333.429 451.625 1.00 86.00  ? 222 THR B CB  1 
ATOM 5021 O OG1 . THR D 4 222 ? 335.712 332.237 452.339 1.00 86.00  ? 222 THR B OG1 1 
ATOM 5022 C CG2 . THR D 4 222 ? 335.137 334.535 452.619 1.00 86.00  ? 222 THR B CG2 1 
ATOM 5023 N N   . LEU D 4 223 ? 332.402 334.892 450.655 1.00 80.59  ? 223 LEU B N   1 
ATOM 5024 C CA  . LEU D 4 223 ? 331.773 336.108 450.166 1.00 80.59  ? 223 LEU B CA  1 
ATOM 5025 C C   . LEU D 4 223 ? 331.927 337.207 451.207 1.00 80.59  ? 223 LEU B C   1 
ATOM 5026 O O   . LEU D 4 223 ? 331.303 337.147 452.269 1.00 80.59  ? 223 LEU B O   1 
ATOM 5027 C CB  . LEU D 4 223 ? 330.301 335.864 449.864 1.00 80.59  ? 223 LEU B CB  1 
ATOM 5028 C CG  . LEU D 4 223 ? 329.564 337.116 449.418 1.00 80.59  ? 223 LEU B CG  1 
ATOM 5029 C CD1 . LEU D 4 223 ? 329.912 337.410 447.987 1.00 80.59  ? 223 LEU B CD1 1 
ATOM 5030 C CD2 . LEU D 4 223 ? 328.076 336.944 449.578 1.00 80.59  ? 223 LEU B CD2 1 
ATOM 5031 N N   . MET D 4 224 ? 332.742 338.210 450.899 1.00 84.39  ? 224 MET B N   1 
ATOM 5032 C CA  . MET D 4 224 ? 333.047 339.292 451.822 1.00 84.39  ? 224 MET B CA  1 
ATOM 5033 C C   . MET D 4 224 ? 332.340 340.562 451.390 1.00 84.39  ? 224 MET B C   1 
ATOM 5034 O O   . MET D 4 224 ? 332.135 340.790 450.197 1.00 84.39  ? 224 MET B O   1 
ATOM 5035 C CB  . MET D 4 224 ? 334.544 339.556 451.885 1.00 84.39  ? 224 MET B CB  1 
ATOM 5036 C CG  . MET D 4 224 ? 335.325 338.446 452.523 1.00 84.39  ? 224 MET B CG  1 
ATOM 5037 S SD  . MET D 4 224 ? 337.085 338.782 452.577 1.00 84.39  ? 224 MET B SD  1 
ATOM 5038 C CE  . MET D 4 224 ? 337.634 337.444 453.625 1.00 84.39  ? 224 MET B CE  1 
ATOM 5039 N N   . ILE D 4 225 ? 331.964 341.385 452.363 1.00 78.39  ? 225 ILE B N   1 
ATOM 5040 C CA  . ILE D 4 225 ? 331.401 342.707 452.121 1.00 78.39  ? 225 ILE B CA  1 
ATOM 5041 C C   . ILE D 4 225 ? 332.077 343.663 453.086 1.00 78.39  ? 225 ILE B C   1 
ATOM 5042 O O   . ILE D 4 225 ? 331.919 343.525 454.302 1.00 78.39  ? 225 ILE B O   1 
ATOM 5043 C CB  . ILE D 4 225 ? 329.882 342.742 452.327 1.00 78.39  ? 225 ILE B CB  1 
ATOM 5044 C CG1 . ILE D 4 225 ? 329.167 341.940 451.253 1.00 78.39  ? 225 ILE B CG1 1 
ATOM 5045 C CG2 . ILE D 4 225 ? 329.385 344.157 452.289 1.00 78.39  ? 225 ILE B CG2 1 
ATOM 5046 C CD1 . ILE D 4 225 ? 327.718 341.729 451.547 1.00 78.39  ? 225 ILE B CD1 1 
ATOM 5047 N N   . ILE D 4 226 ? 332.838 344.621 452.557 1.00 76.99  ? 226 ILE B N   1 
ATOM 5048 C CA  . ILE D 4 226 ? 333.584 345.564 453.375 1.00 76.99  ? 226 ILE B CA  1 
ATOM 5049 C C   . ILE D 4 226 ? 333.130 346.981 453.049 1.00 76.99  ? 226 ILE B C   1 
ATOM 5050 O O   . ILE D 4 226 ? 333.144 347.378 451.882 1.00 76.99  ? 226 ILE B O   1 
ATOM 5051 C CB  . ILE D 4 226 ? 335.102 345.443 453.170 1.00 76.99  ? 226 ILE B CB  1 
ATOM 5052 C CG1 . ILE D 4 226 ? 335.529 343.986 453.171 1.00 76.99  ? 226 ILE B CG1 1 
ATOM 5053 C CG2 . ILE D 4 226 ? 335.825 346.174 454.263 1.00 76.99  ? 226 ILE B CG2 1 
ATOM 5054 C CD1 . ILE D 4 226 ? 336.986 343.800 452.907 1.00 76.99  ? 226 ILE B CD1 1 
ATOM 5055 N N   . PRO D 4 227 ? 332.720 347.774 454.023 1.00 76.67  ? 227 PRO B N   1 
ATOM 5056 C CA  . PRO D 4 227 ? 332.366 349.172 453.755 1.00 76.67  ? 227 PRO B CA  1 
ATOM 5057 C C   . PRO D 4 227 ? 333.611 350.041 453.733 1.00 76.67  ? 227 PRO B C   1 
ATOM 5058 O O   . PRO D 4 227 ? 334.321 350.154 454.735 1.00 76.67  ? 227 PRO B O   1 
ATOM 5059 C CB  . PRO D 4 227 ? 331.451 349.527 454.934 1.00 76.67  ? 227 PRO B CB  1 
ATOM 5060 C CG  . PRO D 4 227 ? 331.022 348.243 455.492 1.00 76.67  ? 227 PRO B CG  1 
ATOM 5061 C CD  . PRO D 4 227 ? 332.173 347.323 455.304 1.00 76.67  ? 227 PRO B CD  1 
ATOM 5062 N N   . PHE D 4 228 ? 333.877 350.665 452.589 1.00 78.76  ? 228 PHE B N   1 
ATOM 5063 C CA  . PHE D 4 228 ? 335.021 351.564 452.506 1.00 78.76  ? 228 PHE B CA  1 
ATOM 5064 C C   . PHE D 4 228 ? 334.679 352.946 453.039 1.00 78.76  ? 228 PHE B C   1 
ATOM 5065 O O   . PHE D 4 228 ? 335.282 353.417 454.007 1.00 78.76  ? 228 PHE B O   1 
ATOM 5066 C CB  . PHE D 4 228 ? 335.522 351.653 451.069 1.00 78.76  ? 228 PHE B CB  1 
ATOM 5067 C CG  . PHE D 4 228 ? 336.540 350.628 450.739 1.00 78.76  ? 228 PHE B CG  1 
ATOM 5068 C CD1 . PHE D 4 228 ? 337.760 350.635 451.374 1.00 78.76  ? 228 PHE B CD1 1 
ATOM 5069 C CD2 . PHE D 4 228 ? 336.280 349.656 449.806 1.00 78.76  ? 228 PHE B CD2 1 
ATOM 5070 C CE1 . PHE D 4 228 ? 338.702 349.692 451.083 1.00 78.76  ? 228 PHE B CE1 1 
ATOM 5071 C CE2 . PHE D 4 228 ? 337.221 348.709 449.509 1.00 78.76  ? 228 PHE B CE2 1 
ATOM 5072 C CZ  . PHE D 4 228 ? 338.434 348.726 450.150 1.00 78.76  ? 228 PHE B CZ  1 
ATOM 5073 N N   . VAL D 4 229 ? 333.726 353.618 452.410 1.00 79.04  ? 229 VAL B N   1 
ATOM 5074 C CA  . VAL D 4 229 ? 333.197 354.879 452.915 1.00 79.04  ? 229 VAL B CA  1 
ATOM 5075 C C   . VAL D 4 229 ? 332.031 354.548 453.837 1.00 79.04  ? 229 VAL B C   1 
ATOM 5076 O O   . VAL D 4 229 ? 331.037 353.979 453.368 1.00 79.04  ? 229 VAL B O   1 
ATOM 5077 C CB  . VAL D 4 229 ? 332.749 355.798 451.779 1.00 79.04  ? 229 VAL B CB  1 
ATOM 5078 C CG1 . VAL D 4 229 ? 332.331 357.130 452.339 1.00 79.04  ? 229 VAL B CG1 1 
ATOM 5079 C CG2 . VAL D 4 229 ? 333.869 355.964 450.789 1.00 79.04  ? 229 VAL B CG2 1 
ATOM 5080 N N   . PRO D 4 230 ? 332.107 354.875 455.120 1.00 82.38  ? 230 PRO B N   1 
ATOM 5081 C CA  . PRO D 4 230 ? 331.103 354.397 456.068 1.00 82.38  ? 230 PRO B CA  1 
ATOM 5082 C C   . PRO D 4 230 ? 329.788 355.130 455.890 1.00 82.38  ? 230 PRO B C   1 
ATOM 5083 O O   . PRO D 4 230 ? 329.704 356.168 455.237 1.00 82.38  ? 230 PRO B O   1 
ATOM 5084 C CB  . PRO D 4 230 ? 331.735 354.710 457.418 1.00 82.38  ? 230 PRO B CB  1 
ATOM 5085 C CG  . PRO D 4 230 ? 332.512 355.932 457.150 1.00 82.38  ? 230 PRO B CG  1 
ATOM 5086 C CD  . PRO D 4 230 ? 333.052 355.801 455.756 1.00 82.38  ? 230 PRO B CD  1 
ATOM 5087 N N   . LEU D 4 231 ? 328.747 354.551 456.474 1.00 86.80  ? 231 LEU B N   1 
ATOM 5088 C CA  . LEU D 4 231 ? 327.407 355.092 456.328 1.00 86.80  ? 231 LEU B CA  1 
ATOM 5089 C C   . LEU D 4 231 ? 327.275 356.391 457.102 1.00 86.80  ? 231 LEU B C   1 
ATOM 5090 O O   . LEU D 4 231 ? 327.700 356.493 458.253 1.00 86.80  ? 231 LEU B O   1 
ATOM 5091 C CB  . LEU D 4 231 ? 326.380 354.082 456.819 1.00 86.80  ? 231 LEU B CB  1 
ATOM 5092 C CG  . LEU D 4 231 ? 324.931 354.549 456.841 1.00 86.80  ? 231 LEU B CG  1 
ATOM 5093 C CD1 . LEU D 4 231 ? 324.492 354.925 455.454 1.00 86.80  ? 231 LEU B CD1 1 
ATOM 5094 C CD2 . LEU D 4 231 ? 324.041 353.474 457.405 1.00 86.80  ? 231 LEU B CD2 1 
ATOM 5095 N N   . ASN D 4 232 ? 326.704 357.397 456.451 1.00 87.60  ? 232 ASN B N   1 
ATOM 5096 C CA  . ASN D 4 232 ? 326.438 358.669 457.096 1.00 87.60  ? 232 ASN B CA  1 
ATOM 5097 C C   . ASN D 4 232 ? 325.060 359.139 456.670 1.00 87.60  ? 232 ASN B C   1 
ATOM 5098 O O   . ASN D 4 232 ? 324.591 358.809 455.581 1.00 87.60  ? 232 ASN B O   1 
ATOM 5099 C CB  . ASN D 4 232 ? 327.494 359.714 456.739 1.00 87.60  ? 232 ASN B CB  1 
ATOM 5100 C CG  . ASN D 4 232 ? 327.547 360.841 457.738 1.00 87.60  ? 232 ASN B CG  1 
ATOM 5101 O OD1 . ASN D 4 232 ? 327.049 360.711 458.852 1.00 87.60  ? 232 ASN B OD1 1 
ATOM 5102 N ND2 . ASN D 4 232 ? 328.151 361.955 457.349 1.00 87.60  ? 232 ASN B ND2 1 
ATOM 5103 N N   . TYR D 4 233 ? 324.417 359.907 457.539 1.00 87.65  ? 233 TYR B N   1 
ATOM 5104 C CA  . TYR D 4 233 ? 323.080 360.414 457.271 1.00 87.65  ? 233 TYR B CA  1 
ATOM 5105 C C   . TYR D 4 233 ? 322.833 361.594 458.191 1.00 87.65  ? 233 TYR B C   1 
ATOM 5106 O O   . TYR D 4 233 ? 323.617 361.872 459.097 1.00 87.65  ? 233 TYR B O   1 
ATOM 5107 C CB  . TYR D 4 233 ? 322.012 359.342 457.484 1.00 87.65  ? 233 TYR B CB  1 
ATOM 5108 C CG  . TYR D 4 233 ? 322.149 358.587 458.781 1.00 87.65  ? 233 TYR B CG  1 
ATOM 5109 C CD1 . TYR D 4 233 ? 321.564 359.055 459.948 1.00 87.65  ? 233 TYR B CD1 1 
ATOM 5110 C CD2 . TYR D 4 233 ? 322.842 357.396 458.834 1.00 87.65  ? 233 TYR B CD2 1 
ATOM 5111 C CE1 . TYR D 4 233 ? 321.687 358.369 461.126 1.00 87.65  ? 233 TYR B CE1 1 
ATOM 5112 C CE2 . TYR D 4 233 ? 322.963 356.704 460.005 1.00 87.65  ? 233 TYR B CE2 1 
ATOM 5113 C CZ  . TYR D 4 233 ? 322.388 357.195 461.147 1.00 87.65  ? 233 TYR B CZ  1 
ATOM 5114 O OH  . TYR D 4 233 ? 322.512 356.499 462.321 1.00 87.65  ? 233 TYR B OH  1 
ATOM 5115 N N   . SER D 4 234 ? 321.714 362.266 457.970 1.00 96.60  ? 234 SER B N   1 
ATOM 5116 C CA  . SER D 4 234 ? 321.330 363.333 458.873 1.00 96.60  ? 234 SER B CA  1 
ATOM 5117 C C   . SER D 4 234 ? 320.321 362.825 459.891 1.00 96.60  ? 234 SER B C   1 
ATOM 5118 O O   . SER D 4 234 ? 319.731 361.753 459.744 1.00 96.60  ? 234 SER B O   1 
ATOM 5119 C CB  . SER D 4 234 ? 320.776 364.515 458.093 1.00 96.60  ? 234 SER B CB  1 
ATOM 5120 O OG  . SER D 4 234 ? 321.647 364.829 457.032 1.00 96.60  ? 234 SER B OG  1 
ATOM 5121 N N   . GLU D 4 235 ? 320.128 363.614 460.941 1.00 103.26 ? 235 GLU B N   1 
ATOM 5122 C CA  . GLU D 4 235 ? 319.188 363.275 461.998 1.00 103.26 ? 235 GLU B CA  1 
ATOM 5123 C C   . GLU D 4 235 ? 317.771 363.390 461.460 1.00 103.26 ? 235 GLU B C   1 
ATOM 5124 O O   . GLU D 4 235 ? 317.366 364.452 460.980 1.00 103.26 ? 235 GLU B O   1 
ATOM 5125 C CB  . GLU D 4 235 ? 319.396 364.195 463.198 1.00 103.26 ? 235 GLU B CB  1 
ATOM 5126 C CG  . GLU D 4 235 ? 318.238 364.242 464.188 1.00 103.26 ? 235 GLU B CG  1 
ATOM 5127 C CD  . GLU D 4 235 ? 318.304 363.167 465.258 1.00 103.26 ? 235 GLU B CD  1 
ATOM 5128 O OE1 . GLU D 4 235 ? 318.984 362.140 465.057 1.00 103.26 ? 235 GLU B OE1 1 
ATOM 5129 O OE2 . GLU D 4 235 ? 317.670 363.357 466.316 1.00 103.26 ? 235 GLU B OE2 1 
ATOM 5130 N N   . GLY D 4 236 ? 317.022 362.290 461.522 1.00 96.58  ? 236 GLY B N   1 
ATOM 5131 C CA  . GLY D 4 236 ? 315.682 362.213 460.972 1.00 96.58  ? 236 GLY B CA  1 
ATOM 5132 C C   . GLY D 4 236 ? 315.478 361.022 460.059 1.00 96.58  ? 236 GLY B C   1 
ATOM 5133 O O   . GLY D 4 236 ? 314.359 360.515 459.949 1.00 96.58  ? 236 GLY B O   1 
ATOM 5134 N N   . SER D 4 237 ? 316.538 360.568 459.404 1.00 94.50  ? 237 SER B N   1 
ATOM 5135 C CA  . SER D 4 237 ? 316.440 359.355 458.618 1.00 94.50  ? 237 SER B CA  1 
ATOM 5136 C C   . SER D 4 237 ? 316.536 358.128 459.518 1.00 94.50  ? 237 SER B C   1 
ATOM 5137 O O   . SER D 4 237 ? 316.704 358.223 460.734 1.00 94.50  ? 237 SER B O   1 
ATOM 5138 C CB  . SER D 4 237 ? 317.534 359.308 457.563 1.00 94.50  ? 237 SER B CB  1 
ATOM 5139 O OG  . SER D 4 237 ? 317.498 358.065 456.895 1.00 94.50  ? 237 SER B OG  1 
ATOM 5140 N N   . SER D 4 238 ? 316.428 356.966 458.903 1.00 87.36  ? 238 SER B N   1 
ATOM 5141 C CA  . SER D 4 238 ? 316.512 355.724 459.653 1.00 87.36  ? 238 SER B CA  1 
ATOM 5142 C C   . SER D 4 238 ? 317.960 355.455 460.031 1.00 87.36  ? 238 SER B C   1 
ATOM 5143 O O   . SER D 4 238 ? 318.854 355.657 459.208 1.00 87.36  ? 238 SER B O   1 
ATOM 5144 C CB  . SER D 4 238 ? 315.971 354.574 458.830 1.00 87.36  ? 238 SER B CB  1 
ATOM 5145 O OG  . SER D 4 238 ? 316.800 354.360 457.707 1.00 87.36  ? 238 SER B OG  1 
ATOM 5146 N N   . PRO D 4 239 ? 318.230 355.001 461.237 1.00 88.39  ? 239 PRO B N   1 
ATOM 5147 C CA  . PRO D 4 239 ? 319.621 354.855 461.675 1.00 88.39  ? 239 PRO B CA  1 
ATOM 5148 C C   . PRO D 4 239 ? 320.276 353.535 461.301 1.00 88.39  ? 239 PRO B C   1 
ATOM 5149 O O   . PRO D 4 239 ? 321.316 353.196 461.868 1.00 88.39  ? 239 PRO B O   1 
ATOM 5150 C CB  . PRO D 4 239 ? 319.512 354.996 463.193 1.00 88.39  ? 239 PRO B CB  1 
ATOM 5151 C CG  . PRO D 4 239 ? 318.169 354.472 463.502 1.00 88.39  ? 239 PRO B CG  1 
ATOM 5152 C CD  . PRO D 4 239 ? 317.287 354.871 462.357 1.00 88.39  ? 239 PRO B CD  1 
ATOM 5153 N N   . TYR D 4 240 ? 319.693 352.772 460.382 1.00 88.16  ? 240 TYR B N   1 
ATOM 5154 C CA  . TYR D 4 240 ? 320.366 351.591 459.867 1.00 88.16  ? 240 TYR B CA  1 
ATOM 5155 C C   . TYR D 4 240 ? 319.910 351.350 458.439 1.00 88.16  ? 240 TYR B C   1 
ATOM 5156 O O   . TYR D 4 240 ? 318.818 351.758 458.048 1.00 88.16  ? 240 TYR B O   1 
ATOM 5157 C CB  . TYR D 4 240 ? 320.104 350.348 460.730 1.00 88.16  ? 240 TYR B CB  1 
ATOM 5158 C CG  . TYR D 4 240 ? 318.650 349.982 460.906 1.00 88.16  ? 240 TYR B CG  1 
ATOM 5159 C CD1 . TYR D 4 240 ? 318.004 349.147 460.000 1.00 88.16  ? 240 TYR B CD1 1 
ATOM 5160 C CD2 . TYR D 4 240 ? 317.926 350.449 461.990 1.00 88.16  ? 240 TYR B CD2 1 
ATOM 5161 C CE1 . TYR D 4 240 ? 316.679 348.811 460.153 1.00 88.16  ? 240 TYR B CE1 1 
ATOM 5162 C CE2 . TYR D 4 240 ? 316.592 350.113 462.154 1.00 88.16  ? 240 TYR B CE2 1 
ATOM 5163 C CZ  . TYR D 4 240 ? 315.979 349.292 461.229 1.00 88.16  ? 240 TYR B CZ  1 
ATOM 5164 O OH  . TYR D 4 240 ? 314.658 348.942 461.371 1.00 88.16  ? 240 TYR B OH  1 
ATOM 5165 N N   . VAL D 4 241 ? 320.747 350.668 457.670 1.00 83.35  ? 241 VAL B N   1 
ATOM 5166 C CA  . VAL D 4 241 ? 320.395 350.292 456.306 1.00 83.35  ? 241 VAL B CA  1 
ATOM 5167 C C   . VAL D 4 241 ? 320.482 348.779 456.185 1.00 83.35  ? 241 VAL B C   1 
ATOM 5168 O O   . VAL D 4 241 ? 321.560 348.210 456.387 1.00 83.35  ? 241 VAL B O   1 
ATOM 5169 C CB  . VAL D 4 241 ? 321.313 350.969 455.284 1.00 83.35  ? 241 VAL B CB  1 
ATOM 5170 C CG1 . VAL D 4 241 ? 321.066 350.395 453.913 1.00 83.35  ? 241 VAL B CG1 1 
ATOM 5171 C CG2 . VAL D 4 241 ? 321.083 352.457 455.284 1.00 83.35  ? 241 VAL B CG2 1 
ATOM 5172 N N   . PRO D 4 242 ? 319.398 348.090 455.867 1.00 83.87  ? 242 PRO B N   1 
ATOM 5173 C CA  . PRO D 4 242 ? 319.462 346.636 455.753 1.00 83.87  ? 242 PRO B CA  1 
ATOM 5174 C C   . PRO D 4 242 ? 320.080 346.190 454.441 1.00 83.87  ? 242 PRO B C   1 
ATOM 5175 O O   . PRO D 4 242 ? 319.901 346.810 453.393 1.00 83.87  ? 242 PRO B O   1 
ATOM 5176 C CB  . PRO D 4 242 ? 317.993 346.219 455.837 1.00 83.87  ? 242 PRO B CB  1 
ATOM 5177 C CG  . PRO D 4 242 ? 317.267 347.372 455.301 1.00 83.87  ? 242 PRO B CG  1 
ATOM 5178 C CD  . PRO D 4 242 ? 318.028 348.591 455.719 1.00 83.87  ? 242 PRO B CD  1 
ATOM 5179 N N   . ILE D 4 243 ? 320.823 345.094 454.519 1.00 83.59  ? 243 ILE B N   1 
ATOM 5180 C CA  . ILE D 4 243 ? 321.430 344.449 453.364 1.00 83.59  ? 243 ILE B CA  1 
ATOM 5181 C C   . ILE D 4 243 ? 320.882 343.038 453.277 1.00 83.59  ? 243 ILE B C   1 
ATOM 5182 O O   . ILE D 4 243 ? 320.957 342.281 454.248 1.00 83.59  ? 243 ILE B O   1 
ATOM 5183 C CB  . ILE D 4 243 ? 322.963 344.409 453.481 1.00 83.59  ? 243 ILE B CB  1 
ATOM 5184 C CG1 . ILE D 4 243 ? 323.543 345.811 453.476 1.00 83.59  ? 243 ILE B CG1 1 
ATOM 5185 C CG2 . ILE D 4 243 ? 323.559 343.603 452.363 1.00 83.59  ? 243 ILE B CG2 1 
ATOM 5186 C CD1 . ILE D 4 243 ? 325.037 345.825 453.594 1.00 83.59  ? 243 ILE B CD1 1 
ATOM 5187 N N   . THR D 4 244 ? 320.342 342.674 452.120 1.00 86.21  ? 244 THR B N   1 
ATOM 5188 C CA  . THR D 4 244 ? 319.892 341.307 451.899 1.00 86.21  ? 244 THR B CA  1 
ATOM 5189 C C   . THR D 4 244 ? 320.828 340.637 450.908 1.00 86.21  ? 244 THR B C   1 
ATOM 5190 O O   . THR D 4 244 ? 321.325 341.283 449.982 1.00 86.21  ? 244 THR B O   1 
ATOM 5191 C CB  . THR D 4 244 ? 318.441 341.258 451.414 1.00 86.21  ? 244 THR B CB  1 
ATOM 5192 O OG1 . THR D 4 244 ? 318.118 339.922 451.018 1.00 86.21  ? 244 THR B OG1 1 
ATOM 5193 C CG2 . THR D 4 244 ? 318.205 342.196 450.254 1.00 86.21  ? 244 THR B CG2 1 
ATOM 5194 N N   . VAL D 4 245 ? 321.095 339.356 451.125 1.00 85.69  ? 245 VAL B N   1 
ATOM 5195 C CA  . VAL D 4 245 ? 321.980 338.571 450.276 1.00 85.69  ? 245 VAL B CA  1 
ATOM 5196 C C   . VAL D 4 245 ? 321.265 337.282 449.891 1.00 85.69  ? 245 VAL B C   1 
ATOM 5197 O O   . VAL D 4 245 ? 320.679 336.604 450.741 1.00 85.69  ? 245 VAL B O   1 
ATOM 5198 C CB  . VAL D 4 245 ? 323.330 338.319 450.972 1.00 85.69  ? 245 VAL B CB  1 
ATOM 5199 C CG1 . VAL D 4 245 ? 323.144 337.788 452.376 1.00 85.69  ? 245 VAL B CG1 1 
ATOM 5200 C CG2 . VAL D 4 245 ? 324.172 337.356 450.173 1.00 85.69  ? 245 VAL B CG2 1 
ATOM 5201 N N   . THR D 4 246 ? 321.266 336.971 448.601 1.00 88.93  ? 246 THR B N   1 
ATOM 5202 C CA  . THR D 4 246 ? 320.528 335.833 448.079 1.00 88.93  ? 246 THR B CA  1 
ATOM 5203 C C   . THR D 4 246 ? 321.466 334.981 447.248 1.00 88.93  ? 246 THR B C   1 
ATOM 5204 O O   . THR D 4 246 ? 322.069 335.477 446.294 1.00 88.93  ? 246 THR B O   1 
ATOM 5205 C CB  . THR D 4 246 ? 319.344 336.300 447.240 1.00 88.93  ? 246 THR B CB  1 
ATOM 5206 O OG1 . THR D 4 246 ? 318.353 336.869 448.099 1.00 88.93  ? 246 THR B OG1 1 
ATOM 5207 C CG2 . THR D 4 246 ? 318.739 335.144 446.494 1.00 88.93  ? 246 THR B CG2 1 
ATOM 5208 N N   . ILE D 4 247 ? 321.590 333.709 447.606 1.00 92.03  ? 247 ILE B N   1 
ATOM 5209 C CA  . ILE D 4 247 ? 322.469 332.773 446.921 1.00 92.03  ? 247 ILE B CA  1 
ATOM 5210 C C   . ILE D 4 247 ? 321.615 331.801 446.129 1.00 92.03  ? 247 ILE B C   1 
ATOM 5211 O O   . ILE D 4 247 ? 320.503 331.462 446.543 1.00 92.03  ? 247 ILE B O   1 
ATOM 5212 C CB  . ILE D 4 247 ? 323.367 332.029 447.920 1.00 92.03  ? 247 ILE B CB  1 
ATOM 5213 C CG1 . ILE D 4 247 ? 323.785 332.974 449.035 1.00 92.03  ? 247 ILE B CG1 1 
ATOM 5214 C CG2 . ILE D 4 247 ? 324.598 331.510 447.241 1.00 92.03  ? 247 ILE B CG2 1 
ATOM 5215 C CD1 . ILE D 4 247 ? 324.622 332.325 450.092 1.00 92.03  ? 247 ILE B CD1 1 
ATOM 5216 N N   . ALA D 4 248 ? 322.129 331.357 444.995 1.00 101.33 ? 248 ALA B N   1 
ATOM 5217 C CA  . ALA D 4 248 ? 321.398 330.418 444.162 1.00 101.33 ? 248 ALA B CA  1 
ATOM 5218 C C   . ALA D 4 248 ? 322.349 329.392 443.572 1.00 101.33 ? 248 ALA B C   1 
ATOM 5219 O O   . ALA D 4 248 ? 323.223 329.757 442.780 1.00 101.33 ? 248 ALA B O   1 
ATOM 5220 C CB  . ALA D 4 248 ? 320.665 331.151 443.045 1.00 101.33 ? 248 ALA B CB  1 
ATOM 5221 N N   . PRO D 4 249 ? 322.222 328.117 443.927 1.00 105.11 ? 249 PRO B N   1 
ATOM 5222 C CA  . PRO D 4 249 ? 323.147 327.113 443.400 1.00 105.11 ? 249 PRO B CA  1 
ATOM 5223 C C   . PRO D 4 249 ? 322.915 326.849 441.926 1.00 105.11 ? 249 PRO B C   1 
ATOM 5224 O O   . PRO D 4 249 ? 321.827 327.073 441.396 1.00 105.11 ? 249 PRO B O   1 
ATOM 5225 C CB  . PRO D 4 249 ? 322.837 325.870 444.237 1.00 105.11 ? 249 PRO B CB  1 
ATOM 5226 C CG  . PRO D 4 249 ? 322.163 326.382 445.439 1.00 105.11 ? 249 PRO B CG  1 
ATOM 5227 C CD  . PRO D 4 249 ? 321.381 327.565 444.994 1.00 105.11 ? 249 PRO B CD  1 
ATOM 5228 N N   . MET D 4 250 ? 323.968 326.385 441.267 1.00 122.04 ? 250 MET B N   1 
ATOM 5229 C CA  . MET D 4 250 ? 323.934 325.992 439.868 1.00 122.04 ? 250 MET B CA  1 
ATOM 5230 C C   . MET D 4 250 ? 324.941 324.875 439.673 1.00 122.04 ? 250 MET B C   1 
ATOM 5231 O O   . MET D 4 250 ? 325.901 324.775 440.441 1.00 122.04 ? 250 MET B O   1 
ATOM 5232 C CB  . MET D 4 250 ? 324.263 327.164 438.950 1.00 122.04 ? 250 MET B CB  1 
ATOM 5233 C CG  . MET D 4 250 ? 323.056 327.908 438.440 1.00 122.04 ? 250 MET B CG  1 
ATOM 5234 S SD  . MET D 4 250 ? 323.515 329.435 437.608 1.00 122.04 ? 250 MET B SD  1 
ATOM 5235 C CE  . MET D 4 250 ? 324.970 328.907 436.707 1.00 122.04 ? 250 MET B CE  1 
ATOM 5236 N N   . CYS D 4 251 ? 324.701 324.039 438.658 1.00 140.37 ? 251 CYS B N   1 
ATOM 5237 C CA  . CYS D 4 251 ? 325.533 322.889 438.274 1.00 140.37 ? 251 CYS B CA  1 
ATOM 5238 C C   . CYS D 4 251 ? 325.832 321.966 439.463 1.00 140.37 ? 251 CYS B C   1 
ATOM 5239 O O   . CYS D 4 251 ? 326.932 321.439 439.632 1.00 140.37 ? 251 CYS B O   1 
ATOM 5240 C CB  . CYS D 4 251 ? 326.809 323.342 437.537 1.00 140.37 ? 251 CYS B CB  1 
ATOM 5241 S SG  . CYS D 4 251 ? 328.234 324.041 438.434 1.00 140.37 ? 251 CYS B SG  1 
ATOM 5242 N N   . ALA D 4 252 ? 324.801 321.747 440.274 1.00 150.18 ? 252 ALA B N   1 
ATOM 5243 C CA  . ALA D 4 252 ? 324.915 320.903 441.452 1.00 150.18 ? 252 ALA B CA  1 
ATOM 5244 C C   . ALA D 4 252 ? 324.976 319.439 441.045 1.00 150.18 ? 252 ALA B C   1 
ATOM 5245 O O   . ALA D 4 252 ? 324.089 318.936 440.350 1.00 150.18 ? 252 ALA B O   1 
ATOM 5246 C CB  . ALA D 4 252 ? 323.738 321.136 442.398 1.00 150.18 ? 252 ALA B CB  1 
ATOM 5247 N N   . GLU D 4 253 ? 326.033 318.759 441.479 1.00 154.75 ? 253 GLU B N   1 
ATOM 5248 C CA  . GLU D 4 253 ? 326.230 317.356 441.142 1.00 154.75 ? 253 GLU B CA  1 
ATOM 5249 C C   . GLU D 4 253 ? 326.903 316.663 442.311 1.00 154.75 ? 253 GLU B C   1 
ATOM 5250 O O   . GLU D 4 253 ? 327.757 317.258 442.972 1.00 154.75 ? 253 GLU B O   1 
ATOM 5251 C CB  . GLU D 4 253 ? 327.080 317.199 439.880 1.00 154.75 ? 253 GLU B CB  1 
ATOM 5252 C CG  . GLU D 4 253 ? 326.291 317.202 438.598 1.00 154.75 ? 253 GLU B CG  1 
ATOM 5253 C CD  . GLU D 4 253 ? 326.994 316.452 437.494 1.00 154.75 ? 253 GLU B CD  1 
ATOM 5254 O OE1 . GLU D 4 253 ? 326.419 316.337 436.393 1.00 154.75 ? 253 GLU B OE1 1 
ATOM 5255 O OE2 . GLU D 4 253 ? 328.121 315.970 437.729 1.00 154.75 ? 253 GLU B OE2 1 
ATOM 5256 N N   . TYR D 4 254 ? 326.525 315.415 442.561 1.00 153.94 ? 254 TYR B N   1 
ATOM 5257 C CA  . TYR D 4 254 ? 326.999 314.665 443.711 1.00 153.94 ? 254 TYR B CA  1 
ATOM 5258 C C   . TYR D 4 254 ? 327.507 313.289 443.293 1.00 153.94 ? 254 TYR B C   1 
ATOM 5259 O O   . TYR D 4 254 ? 327.630 312.979 442.105 1.00 153.94 ? 254 TYR B O   1 
ATOM 5260 C CB  . TYR D 4 254 ? 325.886 314.554 444.746 1.00 153.94 ? 254 TYR B CB  1 
ATOM 5261 C CG  . TYR D 4 254 ? 325.255 315.874 445.069 1.00 153.94 ? 254 TYR B CG  1 
ATOM 5262 C CD1 . TYR D 4 254 ? 326.013 316.911 445.592 1.00 153.94 ? 254 TYR B CD1 1 
ATOM 5263 C CD2 . TYR D 4 254 ? 323.912 316.094 444.834 1.00 153.94 ? 254 TYR B CD2 1 
ATOM 5264 C CE1 . TYR D 4 254 ? 325.447 318.126 445.877 1.00 153.94 ? 254 TYR B CE1 1 
ATOM 5265 C CE2 . TYR D 4 254 ? 323.339 317.301 445.120 1.00 153.94 ? 254 TYR B CE2 1 
ATOM 5266 C CZ  . TYR D 4 254 ? 324.107 318.312 445.639 1.00 153.94 ? 254 TYR B CZ  1 
ATOM 5267 O OH  . TYR D 4 254 ? 323.520 319.516 445.920 1.00 153.94 ? 254 TYR B OH  1 
ATOM 5268 N N   . ASN D 4 255 ? 327.791 312.452 444.290 1.00 160.89 ? 255 ASN B N   1 
ATOM 5269 C CA  . ASN D 4 255 ? 328.389 311.137 444.081 1.00 160.89 ? 255 ASN B CA  1 
ATOM 5270 C C   . ASN D 4 255 ? 327.651 310.165 444.988 1.00 160.89 ? 255 ASN B C   1 
ATOM 5271 O O   . ASN D 4 255 ? 327.567 310.387 446.199 1.00 160.89 ? 255 ASN B O   1 
ATOM 5272 C CB  . ASN D 4 255 ? 329.889 311.171 444.392 1.00 160.89 ? 255 ASN B CB  1 
ATOM 5273 C CG  . ASN D 4 255 ? 330.609 309.855 444.091 1.00 160.89 ? 255 ASN B CG  1 
ATOM 5274 O OD1 . ASN D 4 255 ? 330.289 308.793 444.626 1.00 160.89 ? 255 ASN B OD1 1 
ATOM 5275 N ND2 . ASN D 4 255 ? 331.611 309.938 443.224 1.00 160.89 ? 255 ASN B ND2 1 
ATOM 5276 N N   . GLY D 4 256 ? 327.132 309.091 444.409 1.00 165.15 ? 256 GLY B N   1 
ATOM 5277 C CA  . GLY D 4 256 ? 326.468 308.064 445.187 1.00 165.15 ? 256 GLY B CA  1 
ATOM 5278 C C   . GLY D 4 256 ? 325.771 307.084 444.274 1.00 165.15 ? 256 GLY B C   1 
ATOM 5279 O O   . GLY D 4 256 ? 325.169 307.453 443.261 1.00 165.15 ? 256 GLY B O   1 
ATOM 5280 N N   . LEU D 4 257 ? 325.858 305.814 444.653 1.00 167.67 ? 257 LEU B N   1 
ATOM 5281 C CA  . LEU D 4 257 ? 325.282 304.750 443.841 1.00 167.67 ? 257 LEU B CA  1 
ATOM 5282 C C   . LEU D 4 257 ? 323.828 304.501 444.221 1.00 167.67 ? 257 LEU B C   1 
ATOM 5283 O O   . LEU D 4 257 ? 322.913 304.871 443.484 1.00 167.67 ? 257 LEU B O   1 
ATOM 5284 C CB  . LEU D 4 257 ? 326.090 303.459 443.984 1.00 167.67 ? 257 LEU B CB  1 
ATOM 5285 C CG  . LEU D 4 257 ? 325.822 302.414 442.900 1.00 167.67 ? 257 LEU B CG  1 
ATOM 5286 C CD1 . LEU D 4 257 ? 326.646 302.727 441.666 1.00 167.67 ? 257 LEU B CD1 1 
ATOM 5287 C CD2 . LEU D 4 257 ? 326.107 301.004 443.398 1.00 167.67 ? 257 LEU B CD2 1 
ATOM 5288 N N   . GLY E 5 1   ? 388.081 305.749 420.286 1.00 111.66 ? 1   GLY C N   1 
ATOM 5289 C CA  . GLY E 5 1   ? 386.995 305.744 419.323 1.00 111.66 ? 1   GLY C CA  1 
ATOM 5290 C C   . GLY E 5 1   ? 386.856 307.073 418.614 1.00 111.66 ? 1   GLY C C   1 
ATOM 5291 O O   . GLY E 5 1   ? 387.770 307.506 417.919 1.00 111.66 ? 1   GLY C O   1 
ATOM 5292 N N   . LEU E 5 2   ? 385.711 307.713 418.783 1.00 108.05 ? 2   LEU C N   1 
ATOM 5293 C CA  . LEU E 5 2   ? 385.508 309.054 418.251 1.00 108.05 ? 2   LEU C CA  1 
ATOM 5294 C C   . LEU E 5 2   ? 386.339 310.043 419.055 1.00 108.05 ? 2   LEU C C   1 
ATOM 5295 O O   . LEU E 5 2   ? 386.299 310.004 420.290 1.00 108.05 ? 2   LEU C O   1 
ATOM 5296 C CB  . LEU E 5 2   ? 384.036 309.420 418.315 1.00 108.05 ? 2   LEU C CB  1 
ATOM 5297 C CG  . LEU E 5 2   ? 383.666 310.832 417.884 1.00 108.05 ? 2   LEU C CG  1 
ATOM 5298 C CD1 . LEU E 5 2   ? 383.787 310.979 416.389 1.00 108.05 ? 2   LEU C CD1 1 
ATOM 5299 C CD2 . LEU E 5 2   ? 382.264 311.148 418.332 1.00 108.05 ? 2   LEU C CD2 1 
ATOM 5300 N N   . PRO E 5 3   ? 387.117 310.920 418.419 1.00 102.37 ? 3   PRO C N   1 
ATOM 5301 C CA  . PRO E 5 3   ? 387.979 311.839 419.176 1.00 102.37 ? 3   PRO C CA  1 
ATOM 5302 C C   . PRO E 5 3   ? 387.228 313.114 419.524 1.00 102.37 ? 3   PRO C C   1 
ATOM 5303 O O   . PRO E 5 3   ? 386.586 313.719 418.666 1.00 102.37 ? 3   PRO C O   1 
ATOM 5304 C CB  . PRO E 5 3   ? 389.133 312.118 418.207 1.00 102.37 ? 3   PRO C CB  1 
ATOM 5305 C CG  . PRO E 5 3   ? 388.882 311.239 417.012 1.00 102.37 ? 3   PRO C CG  1 
ATOM 5306 C CD  . PRO E 5 3   ? 387.432 310.959 416.990 1.00 102.37 ? 3   PRO C CD  1 
ATOM 5307 N N   . VAL E 5 4   ? 387.309 313.524 420.787 1.00 102.96 ? 4   VAL C N   1 
ATOM 5308 C CA  . VAL E 5 4   ? 386.679 314.761 421.231 1.00 102.96 ? 4   VAL C CA  1 
ATOM 5309 C C   . VAL E 5 4   ? 387.705 315.620 421.947 1.00 102.96 ? 4   VAL C C   1 
ATOM 5310 O O   . VAL E 5 4   ? 388.878 315.250 422.048 1.00 102.96 ? 4   VAL C O   1 
ATOM 5311 C CB  . VAL E 5 4   ? 385.479 314.493 422.149 1.00 102.96 ? 4   VAL C CB  1 
ATOM 5312 C CG1 . VAL E 5 4   ? 384.367 313.809 421.394 1.00 102.96 ? 4   VAL C CG1 1 
ATOM 5313 C CG2 . VAL E 5 4   ? 385.917 313.653 423.311 1.00 102.96 ? 4   VAL C CG2 1 
ATOM 5314 N N   . MET E 5 5   ? 387.262 316.763 422.466 1.00 106.96 ? 5   MET C N   1 
ATOM 5315 C CA  . MET E 5 5   ? 388.158 317.726 423.101 1.00 106.96 ? 5   MET C CA  1 
ATOM 5316 C C   . MET E 5 5   ? 387.312 318.600 424.013 1.00 106.96 ? 5   MET C C   1 
ATOM 5317 O O   . MET E 5 5   ? 386.325 319.185 423.560 1.00 106.96 ? 5   MET C O   1 
ATOM 5318 C CB  . MET E 5 5   ? 388.876 318.558 422.054 1.00 106.96 ? 5   MET C CB  1 
ATOM 5319 C CG  . MET E 5 5   ? 389.843 319.569 422.617 1.00 106.96 ? 5   MET C CG  1 
ATOM 5320 S SD  . MET E 5 5   ? 390.449 320.684 421.344 1.00 106.96 ? 5   MET C SD  1 
ATOM 5321 C CE  . MET E 5 5   ? 390.668 319.552 419.975 1.00 106.96 ? 5   MET C CE  1 
ATOM 5322 N N   . THR E 5 6   ? 387.689 318.690 425.283 1.00 102.89 ? 6   THR C N   1 
ATOM 5323 C CA  . THR E 5 6   ? 386.882 319.415 426.253 1.00 102.89 ? 6   THR C CA  1 
ATOM 5324 C C   . THR E 5 6   ? 387.265 320.886 426.294 1.00 102.89 ? 6   THR C C   1 
ATOM 5325 O O   . THR E 5 6   ? 388.395 321.234 426.645 1.00 102.89 ? 6   THR C O   1 
ATOM 5326 C CB  . THR E 5 6   ? 387.046 318.806 427.638 1.00 102.89 ? 6   THR C CB  1 
ATOM 5327 O OG1 . THR E 5 6   ? 388.371 319.073 428.110 1.00 102.89 ? 6   THR C OG1 1 
ATOM 5328 C CG2 . THR E 5 6   ? 386.828 317.314 427.583 1.00 102.89 ? 6   THR C CG2 1 
ATOM 5329 N N   . THR E 5 7   ? 386.317 321.744 425.956 1.00 98.58  ? 7   THR C N   1 
ATOM 5330 C CA  . THR E 5 7   ? 386.486 323.181 426.055 1.00 98.58  ? 7   THR C CA  1 
ATOM 5331 C C   . THR E 5 7   ? 386.441 323.597 427.519 1.00 98.58  ? 7   THR C C   1 
ATOM 5332 O O   . THR E 5 7   ? 385.894 322.879 428.354 1.00 98.58  ? 7   THR C O   1 
ATOM 5333 C CB  . THR E 5 7   ? 385.393 323.863 425.236 1.00 98.58  ? 7   THR C CB  1 
ATOM 5334 O OG1 . THR E 5 7   ? 385.385 325.271 425.485 1.00 98.58  ? 7   THR C OG1 1 
ATOM 5335 C CG2 . THR E 5 7   ? 384.041 323.292 425.583 1.00 98.58  ? 7   THR C CG2 1 
ATOM 5336 N N   . PRO E 5 8   ? 387.053 324.729 427.875 1.00 95.86  ? 8   PRO C N   1 
ATOM 5337 C CA  . PRO E 5 8   ? 386.915 325.236 429.243 1.00 95.86  ? 8   PRO C CA  1 
ATOM 5338 C C   . PRO E 5 8   ? 385.491 325.651 429.551 1.00 95.86  ? 8   PRO C C   1 
ATOM 5339 O O   . PRO E 5 8   ? 384.710 325.996 428.665 1.00 95.86  ? 8   PRO C O   1 
ATOM 5340 C CB  . PRO E 5 8   ? 387.855 326.443 429.275 1.00 95.86  ? 8   PRO C CB  1 
ATOM 5341 C CG  . PRO E 5 8   ? 388.124 326.752 427.859 1.00 95.86  ? 8   PRO C CG  1 
ATOM 5342 C CD  . PRO E 5 8   ? 388.130 325.436 427.174 1.00 95.86  ? 8   PRO C CD  1 
ATOM 5343 N N   . GLY E 5 9   ? 385.167 325.620 430.836 1.00 95.46  ? 9   GLY C N   1 
ATOM 5344 C CA  . GLY E 5 9   ? 383.786 325.717 431.244 1.00 95.46  ? 9   GLY C CA  1 
ATOM 5345 C C   . GLY E 5 9   ? 383.058 324.410 431.062 1.00 95.46  ? 9   GLY C C   1 
ATOM 5346 O O   . GLY E 5 9   ? 381.956 324.391 430.506 1.00 95.46  ? 9   GLY C O   1 
ATOM 5347 N N   . SER E 5 10  ? 383.661 323.302 431.493 1.00 97.33  ? 10  SER C N   1 
ATOM 5348 C CA  . SER E 5 10  ? 383.096 321.977 431.273 1.00 97.33  ? 10  SER C CA  1 
ATOM 5349 C C   . SER E 5 10  ? 382.528 321.367 432.549 1.00 97.33  ? 10  SER C C   1 
ATOM 5350 O O   . SER E 5 10  ? 381.366 320.956 432.578 1.00 97.33  ? 10  SER C O   1 
ATOM 5351 C CB  . SER E 5 10  ? 384.159 321.061 430.668 1.00 97.33  ? 10  SER C CB  1 
ATOM 5352 O OG  . SER E 5 10  ? 384.966 320.508 431.684 1.00 97.33  ? 10  SER C OG  1 
ATOM 5353 N N   . THR E 5 11  ? 383.330 321.276 433.599 1.00 96.09  ? 11  THR C N   1 
ATOM 5354 C CA  . THR E 5 11  ? 382.847 320.776 434.884 1.00 96.09  ? 11  THR C CA  1 
ATOM 5355 C C   . THR E 5 11  ? 382.471 321.934 435.803 1.00 96.09  ? 11  THR C C   1 
ATOM 5356 O O   . THR E 5 11  ? 382.998 322.090 436.898 1.00 96.09  ? 11  THR C O   1 
ATOM 5357 C CB  . THR E 5 11  ? 383.891 319.874 435.538 1.00 96.09  ? 11  THR C CB  1 
ATOM 5358 O OG1 . THR E 5 11  ? 384.927 320.673 436.123 1.00 96.09  ? 11  THR C OG1 1 
ATOM 5359 C CG2 . THR E 5 11  ? 384.496 318.929 434.526 1.00 96.09  ? 11  THR C CG2 1 
ATOM 5360 N N   . GLN E 5 12  ? 381.542 322.757 435.343 1.00 86.62  ? 12  GLN C N   1 
ATOM 5361 C CA  . GLN E 5 12  ? 381.087 323.887 436.127 1.00 86.62  ? 12  GLN C CA  1 
ATOM 5362 C C   . GLN E 5 12  ? 379.578 323.829 436.287 1.00 86.62  ? 12  GLN C C   1 
ATOM 5363 O O   . GLN E 5 12  ? 378.880 323.115 435.566 1.00 86.62  ? 12  GLN C O   1 
ATOM 5364 C CB  . GLN E 5 12  ? 381.490 325.208 435.484 1.00 86.62  ? 12  GLN C CB  1 
ATOM 5365 C CG  . GLN E 5 12  ? 380.638 325.586 434.313 1.00 86.62  ? 12  GLN C CG  1 
ATOM 5366 C CD  . GLN E 5 12  ? 380.907 326.986 433.848 1.00 86.62  ? 12  GLN C CD  1 
ATOM 5367 O OE1 . GLN E 5 12  ? 381.886 327.605 434.253 1.00 86.62  ? 12  GLN C OE1 1 
ATOM 5368 N NE2 . GLN E 5 12  ? 380.037 327.502 432.995 1.00 86.62  ? 12  GLN C NE2 1 
ATOM 5369 N N   . PHE E 5 13  ? 379.083 324.589 437.250 1.00 79.33  ? 13  PHE C N   1 
ATOM 5370 C CA  . PHE E 5 13  ? 377.664 324.643 437.569 1.00 79.33  ? 13  PHE C CA  1 
ATOM 5371 C C   . PHE E 5 13  ? 377.245 326.102 437.525 1.00 79.33  ? 13  PHE C C   1 
ATOM 5372 O O   . PHE E 5 13  ? 377.605 326.891 438.396 1.00 79.33  ? 13  PHE C O   1 
ATOM 5373 C CB  . PHE E 5 13  ? 377.393 324.034 438.921 1.00 79.33  ? 13  PHE C CB  1 
ATOM 5374 C CG  . PHE E 5 13  ? 376.020 324.303 439.444 1.00 79.33  ? 13  PHE C CG  1 
ATOM 5375 C CD1 . PHE E 5 13  ? 374.904 324.030 438.681 1.00 79.33  ? 13  PHE C CD1 1 
ATOM 5376 C CD2 . PHE E 5 13  ? 375.846 324.809 440.712 1.00 79.33  ? 13  PHE C CD2 1 
ATOM 5377 C CE1 . PHE E 5 13  ? 373.650 324.280 439.166 1.00 79.33  ? 13  PHE C CE1 1 
ATOM 5378 C CE2 . PHE E 5 13  ? 374.592 325.052 441.204 1.00 79.33  ? 13  PHE C CE2 1 
ATOM 5379 C CZ  . PHE E 5 13  ? 373.494 324.787 440.431 1.00 79.33  ? 13  PHE C CZ  1 
ATOM 5380 N N   . LEU E 5 14  ? 376.474 326.455 436.508 1.00 83.62  ? 14  LEU C N   1 
ATOM 5381 C CA  . LEU E 5 14  ? 375.936 327.799 436.410 1.00 83.62  ? 14  LEU C CA  1 
ATOM 5382 C C   . LEU E 5 14  ? 374.534 327.818 436.988 1.00 83.62  ? 14  LEU C C   1 
ATOM 5383 O O   . LEU E 5 14  ? 373.760 326.883 436.779 1.00 83.62  ? 14  LEU C O   1 
ATOM 5384 C CB  . LEU E 5 14  ? 375.923 328.264 434.960 1.00 83.62  ? 14  LEU C CB  1 
ATOM 5385 C CG  . LEU E 5 14  ? 376.042 329.769 434.790 1.00 83.62  ? 14  LEU C CG  1 
ATOM 5386 C CD1 . LEU E 5 14  ? 377.248 330.278 435.541 1.00 83.62  ? 14  LEU C CD1 1 
ATOM 5387 C CD2 . LEU E 5 14  ? 376.157 330.109 433.329 1.00 83.62  ? 14  LEU C CD2 1 
ATOM 5388 N N   . THR E 5 15  ? 374.208 328.874 437.725 1.00 87.67  ? 15  THR C N   1 
ATOM 5389 C CA  . THR E 5 15  ? 372.919 328.932 438.394 1.00 87.67  ? 15  THR C CA  1 
ATOM 5390 C C   . THR E 5 15  ? 371.770 329.191 437.438 1.00 87.67  ? 15  THR C C   1 
ATOM 5391 O O   . THR E 5 15  ? 370.622 328.905 437.783 1.00 87.67  ? 15  THR C O   1 
ATOM 5392 C CB  . THR E 5 15  ? 372.929 330.013 439.467 1.00 87.67  ? 15  THR C CB  1 
ATOM 5393 O OG1 . THR E 5 15  ? 373.422 331.233 438.906 1.00 87.67  ? 15  THR C OG1 1 
ATOM 5394 C CG2 . THR E 5 15  ? 373.823 329.605 440.607 1.00 87.67  ? 15  THR C CG2 1 
ATOM 5395 N N   . SER E 5 16  ? 372.044 329.726 436.255 1.00 94.55  ? 16  SER C N   1 
ATOM 5396 C CA  . SER E 5 16  ? 371.015 330.024 435.268 1.00 94.55  ? 16  SER C CA  1 
ATOM 5397 C C   . SER E 5 16  ? 371.296 329.320 433.948 1.00 94.55  ? 16  SER C C   1 
ATOM 5398 O O   . SER E 5 16  ? 371.216 329.921 432.878 1.00 94.55  ? 16  SER C O   1 
ATOM 5399 C CB  . SER E 5 16  ? 370.890 331.526 435.047 1.00 94.55  ? 16  SER C CB  1 
ATOM 5400 O OG  . SER E 5 16  ? 371.768 331.954 434.024 1.00 94.55  ? 16  SER C OG  1 
ATOM 5401 N N   . ASP E 5 17  ? 371.652 328.046 434.010 1.00 100.18 ? 17  ASP C N   1 
ATOM 5402 C CA  . ASP E 5 17  ? 371.883 327.262 432.810 1.00 100.18 ? 17  ASP C CA  1 
ATOM 5403 C C   . ASP E 5 17  ? 370.587 326.567 432.406 1.00 100.18 ? 17  ASP C C   1 
ATOM 5404 O O   . ASP E 5 17  ? 369.599 326.577 433.143 1.00 100.18 ? 17  ASP C O   1 
ATOM 5405 C CB  . ASP E 5 17  ? 373.016 326.266 433.043 1.00 100.18 ? 17  ASP C CB  1 
ATOM 5406 C CG  . ASP E 5 17  ? 372.681 325.234 434.107 1.00 100.18 ? 17  ASP C CG  1 
ATOM 5407 O OD1 . ASP E 5 17  ? 371.859 325.530 435.000 1.00 100.18 ? 17  ASP C OD1 1 
ATOM 5408 O OD2 . ASP E 5 17  ? 373.249 324.123 434.057 1.00 100.18 ? 17  ASP C OD2 1 
ATOM 5409 N N   . ASP E 5 18  ? 370.580 325.939 431.232 1.00 108.59 ? 18  ASP C N   1 
ATOM 5410 C CA  . ASP E 5 18  ? 369.431 325.140 430.815 1.00 108.59 ? 18  ASP C CA  1 
ATOM 5411 C C   . ASP E 5 18  ? 369.954 323.970 429.990 1.00 108.59 ? 18  ASP C C   1 
ATOM 5412 O O   . ASP E 5 18  ? 370.120 324.090 428.774 1.00 108.59 ? 18  ASP C O   1 
ATOM 5413 C CB  . ASP E 5 18  ? 368.437 325.973 430.024 1.00 108.59 ? 18  ASP C CB  1 
ATOM 5414 C CG  . ASP E 5 18  ? 367.122 325.261 429.820 1.00 108.59 ? 18  ASP C CG  1 
ATOM 5415 O OD1 . ASP E 5 18  ? 366.885 324.241 430.497 1.00 108.59 ? 18  ASP C OD1 1 
ATOM 5416 O OD2 . ASP E 5 18  ? 366.320 325.724 428.986 1.00 108.59 ? 18  ASP C OD2 1 
ATOM 5417 N N   . PHE E 5 19  ? 370.189 322.845 430.655 1.00 106.92 ? 19  PHE C N   1 
ATOM 5418 C CA  . PHE E 5 19  ? 370.568 321.616 429.985 1.00 106.92 ? 19  PHE C CA  1 
ATOM 5419 C C   . PHE E 5 19  ? 369.544 320.555 430.333 1.00 106.92 ? 19  PHE C C   1 
ATOM 5420 O O   . PHE E 5 19  ? 368.855 320.647 431.350 1.00 106.92 ? 19  PHE C O   1 
ATOM 5421 C CB  . PHE E 5 19  ? 371.966 321.154 430.387 1.00 106.92 ? 19  PHE C CB  1 
ATOM 5422 C CG  . PHE E 5 19  ? 373.032 322.157 430.102 1.00 106.92 ? 19  PHE C CG  1 
ATOM 5423 C CD1 . PHE E 5 19  ? 373.437 322.399 428.805 1.00 106.92 ? 19  PHE C CD1 1 
ATOM 5424 C CD2 . PHE E 5 19  ? 373.627 322.860 431.130 1.00 106.92 ? 19  PHE C CD2 1 
ATOM 5425 C CE1 . PHE E 5 19  ? 374.420 323.322 428.539 1.00 106.92 ? 19  PHE C CE1 1 
ATOM 5426 C CE2 . PHE E 5 19  ? 374.610 323.786 430.871 1.00 106.92 ? 19  PHE C CE2 1 
ATOM 5427 C CZ  . PHE E 5 19  ? 375.007 324.017 429.573 1.00 106.92 ? 19  PHE C CZ  1 
ATOM 5428 N N   . GLN E 5 20  ? 369.443 319.552 429.471 1.00 112.19 ? 20  GLN C N   1 
ATOM 5429 C CA  . GLN E 5 20  ? 368.473 318.491 429.684 1.00 112.19 ? 20  GLN C CA  1 
ATOM 5430 C C   . GLN E 5 20  ? 368.908 317.639 430.867 1.00 112.19 ? 20  GLN C C   1 
ATOM 5431 O O   . GLN E 5 20  ? 370.096 317.354 431.034 1.00 112.19 ? 20  GLN C O   1 
ATOM 5432 C CB  . GLN E 5 20  ? 368.336 317.643 428.423 1.00 112.19 ? 20  GLN C CB  1 
ATOM 5433 C CG  . GLN E 5 20  ? 367.158 316.704 428.459 1.00 112.19 ? 20  GLN C CG  1 
ATOM 5434 C CD  . GLN E 5 20  ? 365.842 317.453 428.572 1.00 112.19 ? 20  GLN C CD  1 
ATOM 5435 O OE1 . GLN E 5 20  ? 365.244 317.521 429.645 1.00 112.19 ? 20  GLN C OE1 1 
ATOM 5436 N NE2 . GLN E 5 20  ? 365.386 318.020 427.463 1.00 112.19 ? 20  GLN C NE2 1 
ATOM 5437 N N   . SER E 5 21  ? 367.952 317.253 431.701 1.00 100.73 ? 21  SER C N   1 
ATOM 5438 C CA  . SER E 5 21  ? 368.282 316.647 432.972 1.00 100.73 ? 21  SER C CA  1 
ATOM 5439 C C   . SER E 5 21  ? 367.765 315.219 433.056 1.00 100.73 ? 21  SER C C   1 
ATOM 5440 O O   . SER E 5 21  ? 366.701 314.916 432.509 1.00 100.73 ? 21  SER C O   1 
ATOM 5441 C CB  . SER E 5 21  ? 367.685 317.464 434.109 1.00 100.73 ? 21  SER C CB  1 
ATOM 5442 O OG  . SER E 5 21  ? 367.525 316.672 435.268 1.00 100.73 ? 21  SER C OG  1 
ATOM 5443 N N   . PRO E 5 22  ? 368.485 314.322 433.730 1.00 98.92  ? 22  PRO C N   1 
ATOM 5444 C CA  . PRO E 5 22  ? 367.971 312.961 433.917 1.00 98.92  ? 22  PRO C CA  1 
ATOM 5445 C C   . PRO E 5 22  ? 366.847 312.949 434.940 1.00 98.92  ? 22  PRO C C   1 
ATOM 5446 O O   . PRO E 5 22  ? 366.897 313.661 435.944 1.00 98.92  ? 22  PRO C O   1 
ATOM 5447 C CB  . PRO E 5 22  ? 369.193 312.187 434.415 1.00 98.92  ? 22  PRO C CB  1 
ATOM 5448 C CG  . PRO E 5 22  ? 370.035 313.210 435.059 1.00 98.92  ? 22  PRO C CG  1 
ATOM 5449 C CD  . PRO E 5 22  ? 369.835 314.478 434.290 1.00 98.92  ? 22  PRO C CD  1 
ATOM 5450 N N   . SER E 5 23  ? 365.824 312.146 434.671 1.00 98.80  ? 23  SER C N   1 
ATOM 5451 C CA  . SER E 5 23  ? 364.705 312.029 435.591 1.00 98.80  ? 23  SER C CA  1 
ATOM 5452 C C   . SER E 5 23  ? 365.064 311.120 436.753 1.00 98.80  ? 23  SER C C   1 
ATOM 5453 O O   . SER E 5 23  ? 365.909 310.233 436.628 1.00 98.80  ? 23  SER C O   1 
ATOM 5454 C CB  . SER E 5 23  ? 363.471 311.488 434.879 1.00 98.80  ? 23  SER C CB  1 
ATOM 5455 O OG  . SER E 5 23  ? 362.601 310.878 435.815 1.00 98.80  ? 23  SER C OG  1 
ATOM 5456 N N   . ALA E 5 24  ? 364.422 311.352 437.893 1.00 97.78  ? 24  ALA C N   1 
ATOM 5457 C CA  . ALA E 5 24  ? 364.623 310.465 439.028 1.00 97.78  ? 24  ALA C CA  1 
ATOM 5458 C C   . ALA E 5 24  ? 363.623 309.325 439.014 1.00 97.78  ? 24  ALA C C   1 
ATOM 5459 O O   . ALA E 5 24  ? 363.993 308.168 439.231 1.00 97.78  ? 24  ALA C O   1 
ATOM 5460 C CB  . ALA E 5 24  ? 364.514 311.239 440.336 1.00 97.78  ? 24  ALA C CB  1 
ATOM 5461 N N   . MET E 5 25  ? 362.354 309.629 438.761 1.00 104.02 ? 25  MET C N   1 
ATOM 5462 C CA  . MET E 5 25  ? 361.298 308.625 438.716 1.00 104.02 ? 25  MET C CA  1 
ATOM 5463 C C   . MET E 5 25  ? 360.729 308.581 437.309 1.00 104.02 ? 25  MET C C   1 
ATOM 5464 O O   . MET E 5 25  ? 359.872 309.400 436.952 1.00 104.02 ? 25  MET C O   1 
ATOM 5465 C CB  . MET E 5 25  ? 360.204 308.928 439.729 1.00 104.02 ? 25  MET C CB  1 
ATOM 5466 C CG  . MET E 5 25  ? 360.671 308.883 441.155 1.00 104.02 ? 25  MET C CG  1 
ATOM 5467 S SD  . MET E 5 25  ? 359.299 308.650 442.294 1.00 104.02 ? 25  MET C SD  1 
ATOM 5468 C CE  . MET E 5 25  ? 358.652 307.085 441.718 1.00 104.02 ? 25  MET C CE  1 
ATOM 5469 N N   . PRO E 5 26  ? 361.174 307.655 436.480 1.00 103.41 ? 26  PRO C N   1 
ATOM 5470 C CA  . PRO E 5 26  ? 360.457 307.352 435.245 1.00 103.41 ? 26  PRO C CA  1 
ATOM 5471 C C   . PRO E 5 26  ? 359.272 306.450 435.565 1.00 103.41 ? 26  PRO C C   1 
ATOM 5472 O O   . PRO E 5 26  ? 359.027 306.106 436.718 1.00 103.41 ? 26  PRO C O   1 
ATOM 5473 C CB  . PRO E 5 26  ? 361.502 306.634 434.385 1.00 103.41 ? 26  PRO C CB  1 
ATOM 5474 C CG  . PRO E 5 26  ? 362.798 306.770 435.121 1.00 103.41 ? 26  PRO C CG  1 
ATOM 5475 C CD  . PRO E 5 26  ? 362.444 306.927 436.556 1.00 103.41 ? 26  PRO C CD  1 
ATOM 5476 N N   . GLN E 5 27  ? 358.548 306.074 434.506 1.00 112.11 ? 27  GLN C N   1 
ATOM 5477 C CA  . GLN E 5 27  ? 357.314 305.283 434.491 1.00 112.11 ? 27  GLN C CA  1 
ATOM 5478 C C   . GLN E 5 27  ? 356.298 305.685 435.563 1.00 112.11 ? 27  GLN C C   1 
ATOM 5479 O O   . GLN E 5 27  ? 355.561 304.844 436.085 1.00 112.11 ? 27  GLN C O   1 
ATOM 5480 C CB  . GLN E 5 27  ? 357.634 303.772 434.551 1.00 112.11 ? 27  GLN C CB  1 
ATOM 5481 C CG  . GLN E 5 27  ? 358.232 303.159 435.831 1.00 112.11 ? 27  GLN C CG  1 
ATOM 5482 C CD  . GLN E 5 27  ? 359.730 303.012 435.769 1.00 112.11 ? 27  GLN C CD  1 
ATOM 5483 O OE1 . GLN E 5 27  ? 360.376 303.536 434.866 1.00 112.11 ? 27  GLN C OE1 1 
ATOM 5484 N NE2 . GLN E 5 27  ? 360.295 302.294 436.733 1.00 112.11 ? 27  GLN C NE2 1 
ATOM 5485 N N   . PHE E 5 28  ? 356.192 306.977 435.851 1.00 109.89 ? 28  PHE C N   1 
ATOM 5486 C CA  . PHE E 5 28  ? 355.299 307.396 436.918 1.00 109.89 ? 28  PHE C CA  1 
ATOM 5487 C C   . PHE E 5 28  ? 353.862 307.590 436.457 1.00 109.89 ? 28  PHE C C   1 
ATOM 5488 O O   . PHE E 5 28  ? 352.957 307.540 437.296 1.00 109.89 ? 28  PHE C O   1 
ATOM 5489 C CB  . PHE E 5 28  ? 355.797 308.688 437.562 1.00 109.89 ? 28  PHE C CB  1 
ATOM 5490 C CG  . PHE E 5 28  ? 355.059 309.045 438.804 1.00 109.89 ? 28  PHE C CG  1 
ATOM 5491 C CD1 . PHE E 5 28  ? 355.216 308.290 439.948 1.00 109.89 ? 28  PHE C CD1 1 
ATOM 5492 C CD2 . PHE E 5 28  ? 354.157 310.089 438.810 1.00 109.89 ? 28  PHE C CD2 1 
ATOM 5493 C CE1 . PHE E 5 28  ? 354.518 308.595 441.094 1.00 109.89 ? 28  PHE C CE1 1 
ATOM 5494 C CE2 . PHE E 5 28  ? 353.451 310.398 439.951 1.00 109.89 ? 28  PHE C CE2 1 
ATOM 5495 C CZ  . PHE E 5 28  ? 353.634 309.650 441.096 1.00 109.89 ? 28  PHE C CZ  1 
ATOM 5496 N N   . ASP E 5 29  ? 353.649 307.775 435.146 1.00 121.00 ? 29  ASP C N   1 
ATOM 5497 C CA  . ASP E 5 29  ? 352.371 308.098 434.481 1.00 121.00 ? 29  ASP C CA  1 
ATOM 5498 C C   . ASP E 5 29  ? 351.615 309.210 435.223 1.00 121.00 ? 29  ASP C C   1 
ATOM 5499 O O   . ASP E 5 29  ? 350.597 309.002 435.882 1.00 121.00 ? 29  ASP C O   1 
ATOM 5500 C CB  . ASP E 5 29  ? 351.512 306.847 434.171 1.00 121.00 ? 29  ASP C CB  1 
ATOM 5501 C CG  . ASP E 5 29  ? 351.285 305.898 435.350 1.00 121.00 ? 29  ASP C CG  1 
ATOM 5502 O OD1 . ASP E 5 29  ? 350.666 306.269 436.364 1.00 121.00 ? 29  ASP C OD1 1 
ATOM 5503 O OD2 . ASP E 5 29  ? 351.620 304.706 435.195 1.00 121.00 ? 29  ASP C OD2 1 
ATOM 5504 N N   . VAL E 5 30  ? 352.215 310.405 435.116 1.00 106.44 ? 30  VAL C N   1 
ATOM 5505 C CA  . VAL E 5 30  ? 351.780 311.639 435.782 1.00 106.44 ? 30  VAL C CA  1 
ATOM 5506 C C   . VAL E 5 30  ? 350.285 311.933 435.580 1.00 106.44 ? 30  VAL C C   1 
ATOM 5507 O O   . VAL E 5 30  ? 349.680 311.582 434.560 1.00 106.44 ? 30  VAL C O   1 
ATOM 5508 C CB  . VAL E 5 30  ? 352.670 312.781 435.254 1.00 106.44 ? 30  VAL C CB  1 
ATOM 5509 C CG1 . VAL E 5 30  ? 352.495 312.971 433.758 1.00 106.44 ? 30  VAL C CG1 1 
ATOM 5510 C CG2 . VAL E 5 30  ? 352.448 314.090 435.984 1.00 106.44 ? 30  VAL C CG2 1 
ATOM 5511 N N   . THR E 5 31  ? 349.674 312.502 436.624 1.00 104.89 ? 31  THR C N   1 
ATOM 5512 C CA  . THR E 5 31  ? 348.272 312.908 436.589 1.00 104.89 ? 31  THR C CA  1 
ATOM 5513 C C   . THR E 5 31  ? 348.049 313.943 435.492 1.00 104.89 ? 31  THR C C   1 
ATOM 5514 O O   . THR E 5 31  ? 348.800 314.920 435.411 1.00 104.89 ? 31  THR C O   1 
ATOM 5515 C CB  . THR E 5 31  ? 347.874 313.478 437.951 1.00 104.89 ? 31  THR C CB  1 
ATOM 5516 O OG1 . THR E 5 31  ? 347.922 312.440 438.936 1.00 104.89 ? 31  THR C OG1 1 
ATOM 5517 C CG2 . THR E 5 31  ? 346.482 314.068 437.924 1.00 104.89 ? 31  THR C CG2 1 
ATOM 5518 N N   . PRO E 5 32  ? 347.049 313.759 434.626 1.00 107.32 ? 32  PRO C N   1 
ATOM 5519 C CA  . PRO E 5 32  ? 346.880 314.657 433.475 1.00 107.32 ? 32  PRO C CA  1 
ATOM 5520 C C   . PRO E 5 32  ? 346.421 316.064 433.820 1.00 107.32 ? 32  PRO C C   1 
ATOM 5521 O O   . PRO E 5 32  ? 346.316 316.442 434.989 1.00 107.32 ? 32  PRO C O   1 
ATOM 5522 C CB  . PRO E 5 32  ? 345.824 313.934 432.634 1.00 107.32 ? 32  PRO C CB  1 
ATOM 5523 C CG  . PRO E 5 32  ? 345.086 313.099 433.610 1.00 107.32 ? 32  PRO C CG  1 
ATOM 5524 C CD  . PRO E 5 32  ? 346.122 312.621 434.564 1.00 107.32 ? 32  PRO C CD  1 
ATOM 5525 N N   . GLU E 5 33  ? 346.147 316.849 432.786 1.00 113.28 ? 33  GLU C N   1 
ATOM 5526 C CA  . GLU E 5 33  ? 345.830 318.258 432.928 1.00 113.28 ? 33  GLU C CA  1 
ATOM 5527 C C   . GLU E 5 33  ? 344.325 318.454 433.098 1.00 113.28 ? 33  GLU C C   1 
ATOM 5528 O O   . GLU E 5 33  ? 343.529 317.521 432.976 1.00 113.28 ? 33  GLU C O   1 
ATOM 5529 C CB  . GLU E 5 33  ? 346.342 319.021 431.715 1.00 113.28 ? 33  GLU C CB  1 
ATOM 5530 C CG  . GLU E 5 33  ? 346.875 320.396 432.011 1.00 113.28 ? 33  GLU C CG  1 
ATOM 5531 C CD  . GLU E 5 33  ? 347.633 320.961 430.841 1.00 113.28 ? 33  GLU C CD  1 
ATOM 5532 O OE1 . GLU E 5 33  ? 347.177 320.773 429.696 1.00 113.28 ? 33  GLU C OE1 1 
ATOM 5533 O OE2 . GLU E 5 33  ? 348.689 321.583 431.063 1.00 113.28 ? 33  GLU C OE2 1 
ATOM 5534 N N   . MET E 5 34  ? 343.929 319.694 433.376 1.00 115.12 ? 34  MET C N   1 
ATOM 5535 C CA  . MET E 5 34  ? 342.527 320.043 433.547 1.00 115.12 ? 34  MET C CA  1 
ATOM 5536 C C   . MET E 5 34  ? 342.348 321.514 433.195 1.00 115.12 ? 34  MET C C   1 
ATOM 5537 O O   . MET E 5 34  ? 343.217 322.331 433.500 1.00 115.12 ? 34  MET C O   1 
ATOM 5538 C CB  . MET E 5 34  ? 342.077 319.762 434.985 1.00 115.12 ? 34  MET C CB  1 
ATOM 5539 C CG  . MET E 5 34  ? 340.686 320.237 435.334 1.00 115.12 ? 34  MET C CG  1 
ATOM 5540 S SD  . MET E 5 34  ? 340.475 320.512 437.091 1.00 115.12 ? 34  MET C SD  1 
ATOM 5541 C CE  . MET E 5 34  ? 339.863 318.911 437.556 1.00 115.12 ? 34  MET C CE  1 
ATOM 5542 N N   . GLN E 5 35  ? 341.234 321.846 432.544 1.00 111.60 ? 35  GLN C N   1 
ATOM 5543 C CA  . GLN E 5 35  ? 340.936 323.242 432.258 1.00 111.60 ? 35  GLN C CA  1 
ATOM 5544 C C   . GLN E 5 35  ? 340.446 323.977 433.499 1.00 111.60 ? 35  GLN C C   1 
ATOM 5545 O O   . GLN E 5 35  ? 339.240 324.170 433.672 1.00 111.60 ? 35  GLN C O   1 
ATOM 5546 C CB  . GLN E 5 35  ? 339.885 323.355 431.156 1.00 111.60 ? 35  GLN C CB  1 
ATOM 5547 C CG  . GLN E 5 35  ? 339.984 322.303 430.073 1.00 111.60 ? 35  GLN C CG  1 
ATOM 5548 C CD  . GLN E 5 35  ? 338.829 322.384 429.092 1.00 111.60 ? 35  GLN C CD  1 
ATOM 5549 O OE1 . GLN E 5 35  ? 338.239 323.446 428.900 1.00 111.60 ? 35  GLN C OE1 1 
ATOM 5550 N NE2 . GLN E 5 35  ? 338.503 321.262 428.466 1.00 111.60 ? 35  GLN C NE2 1 
ATOM 5551 N N   . ILE E 5 36  ? 341.362 324.401 434.358 1.00 100.34 ? 36  ILE C N   1 
ATOM 5552 C CA  . ILE E 5 36  ? 341.009 325.209 435.521 1.00 100.34 ? 36  ILE C CA  1 
ATOM 5553 C C   . ILE E 5 36  ? 340.796 326.637 435.043 1.00 100.34 ? 36  ILE C C   1 
ATOM 5554 O O   . ILE E 5 36  ? 341.634 327.164 434.301 1.00 100.34 ? 36  ILE C O   1 
ATOM 5555 C CB  . ILE E 5 36  ? 342.094 325.125 436.603 1.00 100.34 ? 36  ILE C CB  1 
ATOM 5556 C CG1 . ILE E 5 36  ? 342.134 323.722 437.191 1.00 100.34 ? 36  ILE C CG1 1 
ATOM 5557 C CG2 . ILE E 5 36  ? 341.873 326.141 437.698 1.00 100.34 ? 36  ILE C CG2 1 
ATOM 5558 C CD1 . ILE E 5 36  ? 343.309 323.484 438.087 1.00 100.34 ? 36  ILE C CD1 1 
ATOM 5559 N N   . PRO E 5 37  ? 339.701 327.290 435.417 1.00 95.36  ? 37  PRO C N   1 
ATOM 5560 C CA  . PRO E 5 37  ? 339.451 328.645 434.922 1.00 95.36  ? 37  PRO C CA  1 
ATOM 5561 C C   . PRO E 5 37  ? 340.336 329.672 435.602 1.00 95.36  ? 37  PRO C C   1 
ATOM 5562 O O   . PRO E 5 37  ? 340.723 329.527 436.761 1.00 95.36  ? 37  PRO C O   1 
ATOM 5563 C CB  . PRO E 5 37  ? 337.975 328.881 435.263 1.00 95.36  ? 37  PRO C CB  1 
ATOM 5564 C CG  . PRO E 5 37  ? 337.430 327.536 435.631 1.00 95.36  ? 37  PRO C CG  1 
ATOM 5565 C CD  . PRO E 5 37  ? 338.569 326.782 436.200 1.00 95.36  ? 37  PRO C CD  1 
ATOM 5566 N N   . GLY E 5 38  ? 340.650 330.724 434.859 1.00 93.50  ? 38  GLY C N   1 
ATOM 5567 C CA  . GLY E 5 38  ? 341.428 331.813 435.405 1.00 93.50  ? 38  GLY C CA  1 
ATOM 5568 C C   . GLY E 5 38  ? 342.920 331.614 435.294 1.00 93.50  ? 38  GLY C C   1 
ATOM 5569 O O   . GLY E 5 38  ? 343.627 331.625 436.303 1.00 93.50  ? 38  GLY C O   1 
ATOM 5570 N N   . ARG E 5 39  ? 343.416 331.428 434.078 1.00 93.04  ? 39  ARG C N   1 
ATOM 5571 C CA  . ARG E 5 39  ? 344.838 331.220 433.859 1.00 93.04  ? 39  ARG C CA  1 
ATOM 5572 C C   . ARG E 5 39  ? 345.510 332.539 433.516 1.00 93.04  ? 39  ARG C C   1 
ATOM 5573 O O   . ARG E 5 39  ? 344.980 333.325 432.729 1.00 93.04  ? 39  ARG C O   1 
ATOM 5574 C CB  . ARG E 5 39  ? 345.067 330.206 432.741 1.00 93.04  ? 39  ARG C CB  1 
ATOM 5575 C CG  . ARG E 5 39  ? 346.522 329.880 432.520 1.00 93.04  ? 39  ARG C CG  1 
ATOM 5576 C CD  . ARG E 5 39  ? 346.724 328.869 431.429 1.00 93.04  ? 39  ARG C CD  1 
ATOM 5577 N NE  . ARG E 5 39  ? 348.142 328.724 431.135 1.00 93.04  ? 39  ARG C NE  1 
ATOM 5578 C CZ  . ARG E 5 39  ? 348.659 327.717 430.446 1.00 93.04  ? 39  ARG C CZ  1 
ATOM 5579 N NH1 . ARG E 5 39  ? 349.962 327.663 430.228 1.00 93.04  ? 39  ARG C NH1 1 
ATOM 5580 N NH2 . ARG E 5 39  ? 347.872 326.762 429.978 1.00 93.04  ? 39  ARG C NH2 1 
ATOM 5581 N N   . VAL E 5 40  ? 346.672 332.779 434.112 1.00 94.74  ? 40  VAL C N   1 
ATOM 5582 C CA  . VAL E 5 40  ? 347.489 333.944 433.809 1.00 94.74  ? 40  VAL C CA  1 
ATOM 5583 C C   . VAL E 5 40  ? 348.713 333.476 433.026 1.00 94.74  ? 40  VAL C C   1 
ATOM 5584 O O   . VAL E 5 40  ? 349.292 332.426 433.324 1.00 94.74  ? 40  VAL C O   1 
ATOM 5585 C CB  . VAL E 5 40  ? 347.858 334.712 435.092 1.00 94.74  ? 40  VAL C CB  1 
ATOM 5586 C CG1 . VAL E 5 40  ? 348.586 333.843 436.094 1.00 94.74  ? 40  VAL C CG1 1 
ATOM 5587 C CG2 . VAL E 5 40  ? 348.676 335.940 434.776 1.00 94.74  ? 40  VAL C CG2 1 
ATOM 5588 N N   . ASN E 5 41  ? 349.054 334.199 431.960 1.00 97.18  ? 41  ASN C N   1 
ATOM 5589 C CA  . ASN E 5 41  ? 350.249 333.887 431.190 1.00 97.18  ? 41  ASN C CA  1 
ATOM 5590 C C   . ASN E 5 41  ? 351.203 335.060 431.064 1.00 97.18  ? 41  ASN C C   1 
ATOM 5591 O O   . ASN E 5 41  ? 352.250 334.918 430.428 1.00 97.18  ? 41  ASN C O   1 
ATOM 5592 C CB  . ASN E 5 41  ? 349.874 333.400 429.790 1.00 97.18  ? 41  ASN C CB  1 
ATOM 5593 C CG  . ASN E 5 41  ? 349.010 332.165 429.823 1.00 97.18  ? 41  ASN C CG  1 
ATOM 5594 O OD1 . ASN E 5 41  ? 349.374 331.155 430.424 1.00 97.18  ? 41  ASN C OD1 1 
ATOM 5595 N ND2 . ASN E 5 41  ? 347.860 332.230 429.163 1.00 97.18  ? 41  ASN C ND2 1 
ATOM 5596 N N   . ASN E 5 42  ? 350.868 336.206 431.638 1.00 98.84  ? 42  ASN C N   1 
ATOM 5597 C CA  . ASN E 5 42  ? 351.755 337.355 431.629 1.00 98.84  ? 42  ASN C CA  1 
ATOM 5598 C C   . ASN E 5 42  ? 351.451 338.196 432.854 1.00 98.84  ? 42  ASN C C   1 
ATOM 5599 O O   . ASN E 5 42  ? 350.285 338.427 433.177 1.00 98.84  ? 42  ASN C O   1 
ATOM 5600 C CB  . ASN E 5 42  ? 351.582 338.183 430.361 1.00 98.84  ? 42  ASN C CB  1 
ATOM 5601 C CG  . ASN E 5 42  ? 352.813 338.969 430.019 1.00 98.84  ? 42  ASN C CG  1 
ATOM 5602 O OD1 . ASN E 5 42  ? 353.575 339.357 430.898 1.00 98.84  ? 42  ASN C OD1 1 
ATOM 5603 N ND2 . ASN E 5 42  ? 353.017 339.219 428.735 1.00 98.84  ? 42  ASN C ND2 1 
ATOM 5604 N N   . LEU E 5 43  ? 352.498 338.669 433.522 1.00 99.34  ? 43  LEU C N   1 
ATOM 5605 C CA  . LEU E 5 43  ? 352.300 339.388 434.771 1.00 99.34  ? 43  LEU C CA  1 
ATOM 5606 C C   . LEU E 5 43  ? 351.782 340.802 434.585 1.00 99.34  ? 43  LEU C C   1 
ATOM 5607 O O   . LEU E 5 43  ? 351.483 341.464 435.581 1.00 99.34  ? 43  LEU C O   1 
ATOM 5608 C CB  . LEU E 5 43  ? 353.595 339.444 435.571 1.00 99.34  ? 43  LEU C CB  1 
ATOM 5609 C CG  . LEU E 5 43  ? 353.899 338.219 436.419 1.00 99.34  ? 43  LEU C CG  1 
ATOM 5610 C CD1 . LEU E 5 43  ? 355.051 338.528 437.336 1.00 99.34  ? 43  LEU C CD1 1 
ATOM 5611 C CD2 . LEU E 5 43  ? 352.685 337.804 437.217 1.00 99.34  ? 43  LEU C CD2 1 
ATOM 5612 N N   . MET E 5 44  ? 351.669 341.291 433.355 1.00 108.69 ? 44  MET C N   1 
ATOM 5613 C CA  . MET E 5 44  ? 351.036 342.585 433.165 1.00 108.69 ? 44  MET C CA  1 
ATOM 5614 C C   . MET E 5 44  ? 349.526 342.491 433.275 1.00 108.69 ? 44  MET C C   1 
ATOM 5615 O O   . MET E 5 44  ? 348.859 343.517 433.415 1.00 108.69 ? 44  MET C O   1 
ATOM 5616 C CB  . MET E 5 44  ? 351.442 343.179 431.825 1.00 108.69 ? 44  MET C CB  1 
ATOM 5617 C CG  . MET E 5 44  ? 352.888 343.630 431.775 1.00 108.69 ? 44  MET C CG  1 
ATOM 5618 S SD  . MET E 5 44  ? 353.233 344.982 432.916 1.00 108.69 ? 44  MET C SD  1 
ATOM 5619 C CE  . MET E 5 44  ? 354.206 344.167 434.177 1.00 108.69 ? 44  MET C CE  1 
ATOM 5620 N N   . GLU E 5 45  ? 348.972 341.279 433.223 1.00 106.77 ? 45  GLU C N   1 
ATOM 5621 C CA  . GLU E 5 45  ? 347.541 341.088 433.404 1.00 106.77 ? 45  GLU C CA  1 
ATOM 5622 C C   . GLU E 5 45  ? 347.076 341.426 434.813 1.00 106.77 ? 45  GLU C C   1 
ATOM 5623 O O   . GLU E 5 45  ? 345.940 341.881 434.975 1.00 106.77 ? 45  GLU C O   1 
ATOM 5624 C CB  . GLU E 5 45  ? 347.161 339.647 433.054 1.00 106.77 ? 45  GLU C CB  1 
ATOM 5625 C CG  . GLU E 5 45  ? 345.661 339.356 432.944 1.00 106.77 ? 45  GLU C CG  1 
ATOM 5626 C CD  . GLU E 5 45  ? 344.860 340.455 432.255 1.00 106.77 ? 45  GLU C CD  1 
ATOM 5627 O OE1 . GLU E 5 45  ? 343.806 340.845 432.800 1.00 106.77 ? 45  GLU C OE1 1 
ATOM 5628 O OE2 . GLU E 5 45  ? 345.237 340.889 431.145 1.00 106.77 ? 45  GLU C OE2 1 
ATOM 5629 N N   . ILE E 5 46  ? 347.920 341.232 435.824 1.00 99.16  ? 46  ILE C N   1 
ATOM 5630 C CA  . ILE E 5 46  ? 347.563 341.655 437.172 1.00 99.16  ? 46  ILE C CA  1 
ATOM 5631 C C   . ILE E 5 46  ? 347.512 343.173 437.260 1.00 99.16  ? 46  ILE C C   1 
ATOM 5632 O O   . ILE E 5 46  ? 346.622 343.738 437.903 1.00 99.16  ? 46  ILE C O   1 
ATOM 5633 C CB  . ILE E 5 46  ? 348.545 341.049 438.189 1.00 99.16  ? 46  ILE C CB  1 
ATOM 5634 C CG1 . ILE E 5 46  ? 348.476 339.529 438.125 1.00 99.16  ? 46  ILE C CG1 1 
ATOM 5635 C CG2 . ILE E 5 46  ? 348.242 341.516 439.599 1.00 99.16  ? 46  ILE C CG2 1 
ATOM 5636 C CD1 . ILE E 5 46  ? 349.367 338.838 439.123 1.00 99.16  ? 46  ILE C CD1 1 
ATOM 5637 N N   . ALA E 5 47  ? 348.410 343.863 436.565 1.00 104.80 ? 47  ALA C N   1 
ATOM 5638 C CA  . ALA E 5 47  ? 348.499 345.309 436.700 1.00 104.80 ? 47  ALA C CA  1 
ATOM 5639 C C   . ALA E 5 47  ? 347.384 346.069 435.994 1.00 104.80 ? 47  ALA C C   1 
ATOM 5640 O O   . ALA E 5 47  ? 347.308 347.288 436.152 1.00 104.80 ? 47  ALA C O   1 
ATOM 5641 C CB  . ALA E 5 47  ? 349.847 345.805 436.181 1.00 104.80 ? 47  ALA C CB  1 
ATOM 5642 N N   . GLU E 5 48  ? 346.516 345.408 435.231 1.00 108.92 ? 48  GLU C N   1 
ATOM 5643 C CA  . GLU E 5 48  ? 345.446 346.144 434.570 1.00 108.92 ? 48  GLU C CA  1 
ATOM 5644 C C   . GLU E 5 48  ? 344.260 346.415 435.477 1.00 108.92 ? 48  GLU C C   1 
ATOM 5645 O O   . GLU E 5 48  ? 343.452 347.295 435.164 1.00 108.92 ? 48  GLU C O   1 
ATOM 5646 C CB  . GLU E 5 48  ? 344.942 345.404 433.332 1.00 108.92 ? 48  GLU C CB  1 
ATOM 5647 C CG  . GLU E 5 48  ? 346.016 344.747 432.523 1.00 108.92 ? 48  GLU C CG  1 
ATOM 5648 C CD  . GLU E 5 48  ? 346.815 345.737 431.716 1.00 108.92 ? 48  GLU C CD  1 
ATOM 5649 O OE1 . GLU E 5 48  ? 346.301 346.841 431.447 1.00 108.92 ? 48  GLU C OE1 1 
ATOM 5650 O OE2 . GLU E 5 48  ? 347.965 345.414 431.357 1.00 108.92 ? 48  GLU C OE2 1 
ATOM 5651 N N   . VAL E 5 49  ? 344.116 345.678 436.570 1.00 97.81  ? 49  VAL C N   1 
ATOM 5652 C CA  . VAL E 5 49  ? 342.969 345.892 437.434 1.00 97.81  ? 49  VAL C CA  1 
ATOM 5653 C C   . VAL E 5 49  ? 343.206 347.119 438.307 1.00 97.81  ? 49  VAL C C   1 
ATOM 5654 O O   . VAL E 5 49  ? 344.328 347.604 438.459 1.00 97.81  ? 49  VAL C O   1 
ATOM 5655 C CB  . VAL E 5 49  ? 342.670 344.648 438.280 1.00 97.81  ? 49  VAL C CB  1 
ATOM 5656 C CG1 . VAL E 5 49  ? 342.642 343.424 437.398 1.00 97.81  ? 49  VAL C CG1 1 
ATOM 5657 C CG2 . VAL E 5 49  ? 343.699 344.493 439.357 1.00 97.81  ? 49  VAL C CG2 1 
ATOM 5658 N N   . ASP E 5 50  ? 342.124 347.634 438.872 1.00 96.19  ? 50  ASP C N   1 
ATOM 5659 C CA  . ASP E 5 50  ? 342.158 348.869 439.634 1.00 96.19  ? 50  ASP C CA  1 
ATOM 5660 C C   . ASP E 5 50  ? 342.332 348.553 441.109 1.00 96.19  ? 50  ASP C C   1 
ATOM 5661 O O   . ASP E 5 50  ? 341.788 347.568 441.608 1.00 96.19  ? 50  ASP C O   1 
ATOM 5662 C CB  . ASP E 5 50  ? 340.874 349.664 439.424 1.00 96.19  ? 50  ASP C CB  1 
ATOM 5663 C CG  . ASP E 5 50  ? 340.671 350.057 437.982 1.00 96.19  ? 50  ASP C CG  1 
ATOM 5664 O OD1 . ASP E 5 50  ? 341.669 350.134 437.251 1.00 96.19  ? 50  ASP C OD1 1 
ATOM 5665 O OD2 . ASP E 5 50  ? 339.516 350.295 437.578 1.00 96.19  ? 50  ASP C OD2 1 
ATOM 5666 N N   . SER E 5 51  ? 343.095 349.385 441.804 1.00 87.50  ? 51  SER C N   1 
ATOM 5667 C CA  . SER E 5 51  ? 343.351 349.184 443.218 1.00 87.50  ? 51  SER C CA  1 
ATOM 5668 C C   . SER E 5 51  ? 343.346 350.520 443.934 1.00 87.50  ? 51  SER C C   1 
ATOM 5669 O O   . SER E 5 51  ? 343.765 351.538 443.384 1.00 87.50  ? 51  SER C O   1 
ATOM 5670 C CB  . SER E 5 51  ? 344.668 348.490 443.435 1.00 87.50  ? 51  SER C CB  1 
ATOM 5671 O OG  . SER E 5 51  ? 344.794 347.422 442.527 1.00 87.50  ? 51  SER C OG  1 
ATOM 5672 N N   . VAL E 5 52  ? 342.880 350.502 445.164 1.00 81.96  ? 52  VAL C N   1 
ATOM 5673 C CA  . VAL E 5 52  ? 342.633 351.730 445.903 1.00 81.96  ? 52  VAL C CA  1 
ATOM 5674 C C   . VAL E 5 52  ? 343.946 352.276 446.435 1.00 81.96  ? 52  VAL C C   1 
ATOM 5675 O O   . VAL E 5 52  ? 344.790 351.526 446.930 1.00 81.96  ? 52  VAL C O   1 
ATOM 5676 C CB  . VAL E 5 52  ? 341.633 351.466 447.033 1.00 81.96  ? 52  VAL C CB  1 
ATOM 5677 C CG1 . VAL E 5 52  ? 341.077 352.759 447.541 1.00 81.96  ? 52  VAL C CG1 1 
ATOM 5678 C CG2 . VAL E 5 52  ? 340.523 350.582 446.532 1.00 81.96  ? 52  VAL C CG2 1 
ATOM 5679 N N   . VAL E 5 53  ? 344.124 353.585 446.337 1.00 82.94  ? 53  VAL C N   1 
ATOM 5680 C CA  . VAL E 5 53  ? 345.380 354.243 446.682 1.00 82.94  ? 53  VAL C CA  1 
ATOM 5681 C C   . VAL E 5 53  ? 345.273 354.781 448.103 1.00 82.94  ? 53  VAL C C   1 
ATOM 5682 O O   . VAL E 5 53  ? 344.374 355.585 448.378 1.00 82.94  ? 53  VAL C O   1 
ATOM 5683 C CB  . VAL E 5 53  ? 345.704 355.374 445.704 1.00 82.94  ? 53  VAL C CB  1 
ATOM 5684 C CG1 . VAL E 5 53  ? 347.016 355.992 446.068 1.00 82.94  ? 53  VAL C CG1 1 
ATOM 5685 C CG2 . VAL E 5 53  ? 345.746 354.842 444.298 1.00 82.94  ? 53  VAL C CG2 1 
ATOM 5686 N N   . PRO E 5 54  ? 346.154 354.402 449.004 1.00 83.39  ? 54  PRO C N   1 
ATOM 5687 C CA  . PRO E 5 54  ? 346.108 354.959 450.359 1.00 83.39  ? 54  PRO C CA  1 
ATOM 5688 C C   . PRO E 5 54  ? 346.658 356.371 450.412 1.00 83.39  ? 54  PRO C C   1 
ATOM 5689 O O   . PRO E 5 54  ? 347.787 356.589 450.856 1.00 83.39  ? 54  PRO C O   1 
ATOM 5690 C CB  . PRO E 5 54  ? 346.977 353.989 451.159 1.00 83.39  ? 54  PRO C CB  1 
ATOM 5691 C CG  . PRO E 5 54  ? 347.911 353.423 450.158 1.00 83.39  ? 54  PRO C CG  1 
ATOM 5692 C CD  . PRO E 5 54  ? 347.189 353.371 448.858 1.00 83.39  ? 54  PRO C CD  1 
ATOM 5693 N N   . VAL E 5 55  ? 345.860 357.347 449.989 1.00 85.30  ? 55  VAL C N   1 
ATOM 5694 C CA  . VAL E 5 55  ? 346.352 358.694 449.747 1.00 85.30  ? 55  VAL C CA  1 
ATOM 5695 C C   . VAL E 5 55  ? 346.196 359.593 450.974 1.00 85.30  ? 55  VAL C C   1 
ATOM 5696 O O   . VAL E 5 55  ? 346.583 360.763 450.942 1.00 85.30  ? 55  VAL C O   1 
ATOM 5697 C CB  . VAL E 5 55  ? 345.657 359.275 448.506 1.00 85.30  ? 55  VAL C CB  1 
ATOM 5698 C CG1 . VAL E 5 55  ? 344.297 359.792 448.846 1.00 85.30  ? 55  VAL C CG1 1 
ATOM 5699 C CG2 . VAL E 5 55  ? 346.509 360.308 447.798 1.00 85.30  ? 55  VAL C CG2 1 
ATOM 5700 N N   . ASN E 5 56  ? 345.709 359.055 452.082 1.00 93.28  ? 56  ASN C N   1 
ATOM 5701 C CA  . ASN E 5 56  ? 345.414 359.853 453.265 1.00 93.28  ? 56  ASN C CA  1 
ATOM 5702 C C   . ASN E 5 56  ? 346.124 359.291 454.487 1.00 93.28  ? 56  ASN C C   1 
ATOM 5703 O O   . ASN E 5 56  ? 345.508 359.025 455.520 1.00 93.28  ? 56  ASN C O   1 
ATOM 5704 C CB  . ASN E 5 56  ? 343.914 359.919 453.499 1.00 93.28  ? 56  ASN C CB  1 
ATOM 5705 C CG  . ASN E 5 56  ? 343.525 361.056 454.397 1.00 93.28  ? 56  ASN C CG  1 
ATOM 5706 O OD1 . ASN E 5 56  ? 344.259 362.027 454.527 1.00 93.28  ? 56  ASN C OD1 1 
ATOM 5707 N ND2 . ASN E 5 56  ? 342.378 360.934 455.044 1.00 93.28  ? 56  ASN C ND2 1 
ATOM 5708 N N   . ASN E 5 57  ? 347.436 359.070 454.368 1.00 96.86  ? 57  ASN C N   1 
ATOM 5709 C CA  . ASN E 5 57  ? 348.218 358.373 455.387 1.00 96.86  ? 57  ASN C CA  1 
ATOM 5710 C C   . ASN E 5 57  ? 348.265 359.091 456.729 1.00 96.86  ? 57  ASN C C   1 
ATOM 5711 O O   . ASN E 5 57  ? 347.720 358.591 457.717 1.00 96.86  ? 57  ASN C O   1 
ATOM 5712 C CB  . ASN E 5 57  ? 349.639 358.172 454.884 1.00 96.86  ? 57  ASN C CB  1 
ATOM 5713 C CG  . ASN E 5 57  ? 349.683 357.849 453.427 1.00 96.86  ? 57  ASN C CG  1 
ATOM 5714 O OD1 . ASN E 5 57  ? 350.253 358.590 452.634 1.00 96.86  ? 57  ASN C OD1 1 
ATOM 5715 N ND2 . ASN E 5 57  ? 349.067 356.743 453.053 1.00 96.86  ? 57  ASN C ND2 1 
ATOM 5716 N N   . THR E 5 58  ? 348.909 360.267 456.756 1.00 111.35 ? 58  THR C N   1 
ATOM 5717 C CA  . THR E 5 58  ? 349.098 361.221 457.862 1.00 111.35 ? 58  THR C CA  1 
ATOM 5718 C C   . THR E 5 58  ? 349.346 360.615 459.244 1.00 111.35 ? 58  THR C C   1 
ATOM 5719 O O   . THR E 5 58  ? 348.884 361.164 460.251 1.00 111.35 ? 58  THR C O   1 
ATOM 5720 C CB  . THR E 5 58  ? 347.939 362.245 457.956 1.00 111.35 ? 58  THR C CB  1 
ATOM 5721 O OG1 . THR E 5 58  ? 348.157 363.091 459.091 1.00 111.35 ? 58  THR C OG1 1 
ATOM 5722 C CG2 . THR E 5 58  ? 346.527 361.637 458.083 1.00 111.35 ? 58  THR C CG2 1 
ATOM 5723 N N   . GLU E 5 59  ? 350.043 359.474 459.302 1.00 118.70 ? 59  GLU C N   1 
ATOM 5724 C CA  . GLU E 5 59  ? 350.605 358.871 460.517 1.00 118.70 ? 59  GLU C CA  1 
ATOM 5725 C C   . GLU E 5 59  ? 349.591 358.419 461.563 1.00 118.70 ? 59  GLU C C   1 
ATOM 5726 O O   . GLU E 5 59  ? 349.977 357.857 462.591 1.00 118.70 ? 59  GLU C O   1 
ATOM 5727 C CB  . GLU E 5 59  ? 351.612 359.812 461.184 1.00 118.70 ? 59  GLU C CB  1 
ATOM 5728 C CG  . GLU E 5 59  ? 352.950 359.908 460.481 1.00 118.70 ? 59  GLU C CG  1 
ATOM 5729 C CD  . GLU E 5 59  ? 353.750 358.616 460.564 1.00 118.70 ? 59  GLU C CD  1 
ATOM 5730 O OE1 . GLU E 5 59  ? 353.572 357.859 461.546 1.00 118.70 ? 59  GLU C OE1 1 
ATOM 5731 O OE2 . GLU E 5 59  ? 354.575 358.367 459.664 1.00 118.70 ? 59  GLU C OE2 1 
ATOM 5732 N N   . ASP E 5 60  ? 348.307 358.645 461.324 1.00 117.75 ? 60  ASP C N   1 
ATOM 5733 C CA  . ASP E 5 60  ? 347.283 358.361 462.307 1.00 117.75 ? 60  ASP C CA  1 
ATOM 5734 C C   . ASP E 5 60  ? 346.161 357.526 461.725 1.00 117.75 ? 60  ASP C C   1 
ATOM 5735 O O   . ASP E 5 60  ? 345.570 356.717 462.446 1.00 117.75 ? 60  ASP C O   1 
ATOM 5736 C CB  . ASP E 5 60  ? 346.712 359.670 462.857 1.00 117.75 ? 60  ASP C CB  1 
ATOM 5737 C CG  . ASP E 5 60  ? 347.761 360.511 463.547 1.00 117.75 ? 60  ASP C CG  1 
ATOM 5738 O OD1 . ASP E 5 60  ? 348.694 359.939 464.139 1.00 117.75 ? 60  ASP C OD1 1 
ATOM 5739 O OD2 . ASP E 5 60  ? 347.670 361.753 463.475 1.00 117.75 ? 60  ASP C OD2 1 
ATOM 5740 N N   . ASN E 5 61  ? 345.858 357.694 460.445 1.00 103.01 ? 61  ASN C N   1 
ATOM 5741 C CA  . ASN E 5 61  ? 344.885 356.874 459.759 1.00 103.01 ? 61  ASN C CA  1 
ATOM 5742 C C   . ASN E 5 61  ? 345.542 355.763 458.969 1.00 103.01 ? 61  ASN C C   1 
ATOM 5743 O O   . ASN E 5 61  ? 344.930 355.239 458.034 1.00 103.01 ? 61  ASN C O   1 
ATOM 5744 C CB  . ASN E 5 61  ? 344.041 357.733 458.825 1.00 103.01 ? 61  ASN C CB  1 
ATOM 5745 C CG  . ASN E 5 61  ? 343.575 358.996 459.482 1.00 103.01 ? 61  ASN C CG  1 
ATOM 5746 O OD1 . ASN E 5 61  ? 343.663 359.140 460.698 1.00 103.01 ? 61  ASN C OD1 1 
ATOM 5747 N ND2 . ASN E 5 61  ? 343.075 359.927 458.686 1.00 103.01 ? 61  ASN C ND2 1 
ATOM 5748 N N   . VAL E 5 62  ? 346.780 355.406 459.303 1.00 99.95  ? 62  VAL C N   1 
ATOM 5749 C CA  . VAL E 5 62  ? 347.454 354.349 458.567 1.00 99.95  ? 62  VAL C CA  1 
ATOM 5750 C C   . VAL E 5 62  ? 346.885 352.979 458.923 1.00 99.95  ? 62  VAL C C   1 
ATOM 5751 O O   . VAL E 5 62  ? 346.605 352.169 458.032 1.00 99.95  ? 62  VAL C O   1 
ATOM 5752 C CB  . VAL E 5 62  ? 348.976 354.457 458.785 1.00 99.95  ? 62  VAL C CB  1 
ATOM 5753 C CG1 . VAL E 5 62  ? 349.325 354.606 460.257 1.00 99.95  ? 62  VAL C CG1 1 
ATOM 5754 C CG2 . VAL E 5 62  ? 349.673 353.251 458.216 1.00 99.95  ? 62  VAL C CG2 1 
ATOM 5755 N N   . SER E 5 63  ? 346.658 352.706 460.200 1.00 100.51 ? 63  SER C N   1 
ATOM 5756 C CA  . SER E 5 63  ? 346.133 351.411 460.621 1.00 100.51 ? 63  SER C CA  1 
ATOM 5757 C C   . SER E 5 63  ? 344.619 351.446 460.759 1.00 100.51 ? 63  SER C C   1 
ATOM 5758 O O   . SER E 5 63  ? 344.066 351.026 461.771 1.00 100.51 ? 63  SER C O   1 
ATOM 5759 C CB  . SER E 5 63  ? 346.790 350.987 461.923 1.00 100.51 ? 63  SER C CB  1 
ATOM 5760 O OG  . SER E 5 63  ? 346.875 352.085 462.809 1.00 100.51 ? 63  SER C OG  1 
ATOM 5761 N N   . SER E 5 64  ? 343.939 351.934 459.728 1.00 92.16  ? 64  SER C N   1 
ATOM 5762 C CA  . SER E 5 64  ? 342.484 351.936 459.673 1.00 92.16  ? 64  SER C CA  1 
ATOM 5763 C C   . SER E 5 64  ? 342.068 352.098 458.223 1.00 92.16  ? 64  SER C C   1 
ATOM 5764 O O   . SER E 5 64  ? 342.903 352.238 457.329 1.00 92.16  ? 64  SER C O   1 
ATOM 5765 C CB  . SER E 5 64  ? 341.873 353.049 460.522 1.00 92.16  ? 64  SER C CB  1 
ATOM 5766 O OG  . SER E 5 64  ? 340.544 353.297 460.105 1.00 92.16  ? 64  SER C OG  1 
ATOM 5767 N N   . LEU E 5 65  ? 340.760 352.103 458.000 1.00 89.23  ? 65  LEU C N   1 
ATOM 5768 C CA  . LEU E 5 65  ? 340.203 352.280 456.671 1.00 89.23  ? 65  LEU C CA  1 
ATOM 5769 C C   . LEU E 5 65  ? 340.034 353.741 456.295 1.00 89.23  ? 65  LEU C C   1 
ATOM 5770 O O   . LEU E 5 65  ? 339.424 354.037 455.265 1.00 89.23  ? 65  LEU C O   1 
ATOM 5771 C CB  . LEU E 5 65  ? 338.864 351.563 456.566 1.00 89.23  ? 65  LEU C CB  1 
ATOM 5772 C CG  . LEU E 5 65  ? 338.994 350.133 456.079 1.00 89.23  ? 65  LEU C CG  1 
ATOM 5773 C CD1 . LEU E 5 65  ? 337.671 349.422 456.226 1.00 89.23  ? 65  LEU C CD1 1 
ATOM 5774 C CD2 . LEU E 5 65  ? 339.444 350.147 454.644 1.00 89.23  ? 65  LEU C CD2 1 
ATOM 5775 N N   . LYS E 5 66  ? 340.544 354.660 457.104 1.00 95.80  ? 66  LYS C N   1 
ATOM 5776 C CA  . LYS E 5 66  ? 340.534 356.064 456.731 1.00 95.80  ? 66  LYS C CA  1 
ATOM 5777 C C   . LYS E 5 66  ? 341.729 356.445 455.878 1.00 95.80  ? 66  LYS C C   1 
ATOM 5778 O O   . LYS E 5 66  ? 341.904 357.629 455.581 1.00 95.80  ? 66  LYS C O   1 
ATOM 5779 C CB  . LYS E 5 66  ? 340.489 356.945 457.979 1.00 95.80  ? 66  LYS C CB  1 
ATOM 5780 C CG  . LYS E 5 66  ? 339.188 356.856 458.758 1.00 95.80  ? 66  LYS C CG  1 
ATOM 5781 C CD  . LYS E 5 66  ? 337.988 356.919 457.835 1.00 95.80  ? 66  LYS C CD  1 
ATOM 5782 C CE  . LYS E 5 66  ? 336.693 357.106 458.595 1.00 95.80  ? 66  LYS C CE  1 
ATOM 5783 N NZ  . LYS E 5 66  ? 336.495 356.055 459.623 1.00 95.80  ? 66  LYS C NZ  1 
ATOM 5784 N N   . ALA E 5 67  ? 342.555 355.480 455.485 1.00 91.49  ? 67  ALA C N   1 
ATOM 5785 C CA  . ALA E 5 67  ? 343.685 355.790 454.629 1.00 91.49  ? 67  ALA C CA  1 
ATOM 5786 C C   . ALA E 5 67  ? 343.272 355.977 453.181 1.00 91.49  ? 67  ALA C C   1 
ATOM 5787 O O   . ALA E 5 67  ? 344.009 356.605 452.418 1.00 91.49  ? 67  ALA C O   1 
ATOM 5788 C CB  . ALA E 5 67  ? 344.735 354.690 454.729 1.00 91.49  ? 67  ALA C CB  1 
ATOM 5789 N N   . TYR E 5 68  ? 342.116 355.456 452.787 1.00 87.81  ? 68  TYR C N   1 
ATOM 5790 C CA  . TYR E 5 68  ? 341.675 355.536 451.405 1.00 87.81  ? 68  TYR C CA  1 
ATOM 5791 C C   . TYR E 5 68  ? 340.637 356.616 451.163 1.00 87.81  ? 68  TYR C C   1 
ATOM 5792 O O   . TYR E 5 68  ? 340.188 356.774 450.026 1.00 87.81  ? 68  TYR C O   1 
ATOM 5793 C CB  . TYR E 5 68  ? 341.097 354.195 450.965 1.00 87.81  ? 68  TYR C CB  1 
ATOM 5794 C CG  . TYR E 5 68  ? 342.003 353.034 451.249 1.00 87.81  ? 68  TYR C CG  1 
ATOM 5795 C CD1 . TYR E 5 68  ? 343.155 352.838 450.509 1.00 87.81  ? 68  TYR C CD1 1 
ATOM 5796 C CD2 . TYR E 5 68  ? 341.713 352.136 452.256 1.00 87.81  ? 68  TYR C CD2 1 
ATOM 5797 C CE1 . TYR E 5 68  ? 343.989 351.777 450.761 1.00 87.81  ? 68  TYR C CE1 1 
ATOM 5798 C CE2 . TYR E 5 68  ? 342.542 351.074 452.513 1.00 87.81  ? 68  TYR C CE2 1 
ATOM 5799 C CZ  . TYR E 5 68  ? 343.676 350.901 451.762 1.00 87.81  ? 68  TYR C CZ  1 
ATOM 5800 O OH  . TYR E 5 68  ? 344.504 349.844 452.014 1.00 87.81  ? 68  TYR C OH  1 
ATOM 5801 N N   . GLN E 5 69  ? 340.244 357.354 452.188 1.00 90.30  ? 69  GLN C N   1 
ATOM 5802 C CA  . GLN E 5 69  ? 339.129 358.278 452.102 1.00 90.30  ? 69  GLN C CA  1 
ATOM 5803 C C   . GLN E 5 69  ? 339.616 359.704 452.287 1.00 90.30  ? 69  GLN C C   1 
ATOM 5804 O O   . GLN E 5 69  ? 340.230 360.032 453.305 1.00 90.30  ? 69  GLN C O   1 
ATOM 5805 C CB  . GLN E 5 69  ? 338.086 357.945 453.160 1.00 90.30  ? 69  GLN C CB  1 
ATOM 5806 C CG  . GLN E 5 69  ? 337.948 356.463 453.404 1.00 90.30  ? 69  GLN C CG  1 
ATOM 5807 C CD  . GLN E 5 69  ? 337.031 356.145 454.553 1.00 90.30  ? 69  GLN C CD  1 
ATOM 5808 O OE1 . GLN E 5 69  ? 336.260 356.993 454.994 1.00 90.30  ? 69  GLN C OE1 1 
ATOM 5809 N NE2 . GLN E 5 69  ? 337.121 354.923 455.062 1.00 90.30  ? 69  GLN C NE2 1 
ATOM 5810 N N   . ILE E 5 70  ? 339.332 360.551 451.310 1.00 87.13  ? 70  ILE C N   1 
ATOM 5811 C CA  . ILE E 5 70  ? 339.736 361.951 451.337 1.00 87.13  ? 70  ILE C CA  1 
ATOM 5812 C C   . ILE E 5 70  ? 338.550 362.767 451.831 1.00 87.13  ? 70  ILE C C   1 
ATOM 5813 O O   . ILE E 5 70  ? 337.503 362.767 451.171 1.00 87.13  ? 70  ILE C O   1 
ATOM 5814 C CB  . ILE E 5 70  ? 340.177 362.431 449.955 1.00 87.13  ? 70  ILE C CB  1 
ATOM 5815 C CG1 . ILE E 5 70  ? 340.998 361.352 449.277 1.00 87.13  ? 70  ILE C CG1 1 
ATOM 5816 C CG2 . ILE E 5 70  ? 340.981 363.687 450.089 1.00 87.13  ? 70  ILE C CG2 1 
ATOM 5817 C CD1 . ILE E 5 70  ? 341.206 361.606 447.825 1.00 87.13  ? 70  ILE C CD1 1 
ATOM 5818 N N   . PRO E 5 71  ? 338.657 363.453 452.961 1.00 90.17  ? 71  PRO C N   1 
ATOM 5819 C CA  . PRO E 5 71  ? 337.523 364.239 453.455 1.00 90.17  ? 71  PRO C CA  1 
ATOM 5820 C C   . PRO E 5 71  ? 337.290 365.466 452.589 1.00 90.17  ? 71  PRO C C   1 
ATOM 5821 O O   . PRO E 5 71  ? 338.231 366.155 452.195 1.00 90.17  ? 71  PRO C O   1 
ATOM 5822 C CB  . PRO E 5 71  ? 337.948 364.623 454.875 1.00 90.17  ? 71  PRO C CB  1 
ATOM 5823 C CG  . PRO E 5 71  ? 339.052 363.681 455.214 1.00 90.17  ? 71  PRO C CG  1 
ATOM 5824 C CD  . PRO E 5 71  ? 339.752 363.398 453.935 1.00 90.17  ? 71  PRO C CD  1 
ATOM 5825 N N   . VAL E 5 72  ? 336.024 365.713 452.269 1.00 99.29  ? 72  VAL C N   1 
ATOM 5826 C CA  . VAL E 5 72  ? 335.603 366.857 451.472 1.00 99.29  ? 72  VAL C CA  1 
ATOM 5827 C C   . VAL E 5 72  ? 334.399 367.473 452.165 1.00 99.29  ? 72  VAL C C   1 
ATOM 5828 O O   . VAL E 5 72  ? 333.382 366.797 452.361 1.00 99.29  ? 72  VAL C O   1 
ATOM 5829 C CB  . VAL E 5 72  ? 335.249 366.455 450.032 1.00 99.29  ? 72  VAL C CB  1 
ATOM 5830 C CG1 . VAL E 5 72  ? 334.498 367.567 449.336 1.00 99.29  ? 72  VAL C CG1 1 
ATOM 5831 C CG2 . VAL E 5 72  ? 336.493 366.098 449.255 1.00 99.29  ? 72  VAL C CG2 1 
ATOM 5832 N N   . GLN E 5 73  ? 334.508 368.743 452.543 1.00 106.24 ? 73  GLN C N   1 
ATOM 5833 C CA  . GLN E 5 73  ? 333.412 369.428 453.209 1.00 106.24 ? 73  GLN C CA  1 
ATOM 5834 C C   . GLN E 5 73  ? 333.333 370.862 452.714 1.00 106.24 ? 73  GLN C C   1 
ATOM 5835 O O   . GLN E 5 73  ? 334.290 371.407 452.163 1.00 106.24 ? 73  GLN C O   1 
ATOM 5836 C CB  . GLN E 5 73  ? 333.571 369.392 454.733 1.00 106.24 ? 73  GLN C CB  1 
ATOM 5837 C CG  . GLN E 5 73  ? 334.508 370.434 455.289 1.00 106.24 ? 73  GLN C CG  1 
ATOM 5838 C CD  . GLN E 5 73  ? 335.961 370.078 455.081 1.00 106.24 ? 73  GLN C CD  1 
ATOM 5839 O OE1 . GLN E 5 73  ? 336.289 368.965 454.676 1.00 106.24 ? 73  GLN C OE1 1 
ATOM 5840 N NE2 . GLN E 5 73  ? 336.845 371.026 455.361 1.00 106.24 ? 73  GLN C NE2 1 
ATOM 5841 N N   . SER E 5 74  ? 332.168 371.468 452.915 1.00 111.80 ? 74  SER C N   1 
ATOM 5842 C CA  . SER E 5 74  ? 331.886 372.810 452.414 1.00 111.80 ? 74  SER C CA  1 
ATOM 5843 C C   . SER E 5 74  ? 332.486 373.821 453.376 1.00 111.80 ? 74  SER C C   1 
ATOM 5844 O O   . SER E 5 74  ? 331.858 374.202 454.364 1.00 111.80 ? 74  SER C O   1 
ATOM 5845 C CB  . SER E 5 74  ? 330.386 373.019 452.268 1.00 111.80 ? 74  SER C CB  1 
ATOM 5846 O OG  . SER E 5 74  ? 329.718 372.675 453.468 1.00 111.80 ? 74  SER C OG  1 
ATOM 5847 N N   . ASN E 5 75  ? 333.695 374.271 453.083 1.00 115.53 ? 75  ASN C N   1 
ATOM 5848 C CA  . ASN E 5 75  ? 334.356 375.252 453.925 1.00 115.53 ? 75  ASN C CA  1 
ATOM 5849 C C   . ASN E 5 75  ? 333.898 376.651 453.528 1.00 115.53 ? 75  ASN C C   1 
ATOM 5850 O O   . ASN E 5 75  ? 333.020 376.826 452.681 1.00 115.53 ? 75  ASN C O   1 
ATOM 5851 C CB  . ASN E 5 75  ? 335.867 375.115 453.812 1.00 115.53 ? 75  ASN C CB  1 
ATOM 5852 C CG  . ASN E 5 75  ? 336.380 375.588 452.480 1.00 115.53 ? 75  ASN C CG  1 
ATOM 5853 O OD1 . ASN E 5 75  ? 335.795 375.291 451.442 1.00 115.53 ? 75  ASN C OD1 1 
ATOM 5854 N ND2 . ASN E 5 75  ? 337.463 376.347 452.499 1.00 115.53 ? 75  ASN C ND2 1 
ATOM 5855 N N   . SER E 5 76  ? 334.513 377.669 454.126 1.00 125.17 ? 76  SER C N   1 
ATOM 5856 C CA  . SER E 5 76  ? 334.186 379.054 453.834 1.00 125.17 ? 76  SER C CA  1 
ATOM 5857 C C   . SER E 5 76  ? 335.075 379.669 452.767 1.00 125.17 ? 76  SER C C   1 
ATOM 5858 O O   . SER E 5 76  ? 334.614 380.551 452.035 1.00 125.17 ? 76  SER C O   1 
ATOM 5859 C CB  . SER E 5 76  ? 334.282 379.902 455.108 1.00 125.17 ? 76  SER C CB  1 
ATOM 5860 O OG  . SER E 5 76  ? 335.636 380.094 455.478 1.00 125.17 ? 76  SER C OG  1 
ATOM 5861 N N   . ASP E 5 77  ? 336.325 379.235 452.654 1.00 124.94 ? 77  ASP C N   1 
ATOM 5862 C CA  . ASP E 5 77  ? 337.216 379.731 451.619 1.00 124.94 ? 77  ASP C CA  1 
ATOM 5863 C C   . ASP E 5 77  ? 336.899 379.037 450.304 1.00 124.94 ? 77  ASP C C   1 
ATOM 5864 O O   . ASP E 5 77  ? 336.658 377.828 450.269 1.00 124.94 ? 77  ASP C O   1 
ATOM 5865 C CB  . ASP E 5 77  ? 338.677 379.498 452.014 1.00 124.94 ? 77  ASP C CB  1 
ATOM 5866 C CG  . ASP E 5 77  ? 339.654 379.795 450.886 1.00 124.94 ? 77  ASP C CG  1 
ATOM 5867 O OD1 . ASP E 5 77  ? 339.914 378.903 450.053 1.00 124.94 ? 77  ASP C OD1 1 
ATOM 5868 O OD2 . ASP E 5 77  ? 340.167 380.931 450.832 1.00 124.94 ? 77  ASP C OD2 1 
ATOM 5869 N N   . ASN E 5 78  ? 336.906 379.805 449.220 1.00 122.45 ? 78  ASN C N   1 
ATOM 5870 C CA  . ASN E 5 78  ? 336.684 379.267 447.885 1.00 122.45 ? 78  ASN C CA  1 
ATOM 5871 C C   . ASN E 5 78  ? 338.035 379.017 447.230 1.00 122.45 ? 78  ASN C C   1 
ATOM 5872 O O   . ASN E 5 78  ? 338.659 379.942 446.700 1.00 122.45 ? 78  ASN C O   1 
ATOM 5873 C CB  . ASN E 5 78  ? 335.828 380.208 447.045 1.00 122.45 ? 78  ASN C CB  1 
ATOM 5874 C CG  . ASN E 5 78  ? 334.762 379.470 446.263 1.00 122.45 ? 78  ASN C CG  1 
ATOM 5875 O OD1 . ASN E 5 78  ? 334.897 378.280 445.983 1.00 122.45 ? 78  ASN C OD1 1 
ATOM 5876 N ND2 . ASN E 5 78  ? 333.690 380.169 445.913 1.00 122.45 ? 78  ASN C ND2 1 
ATOM 5877 N N   . GLY E 5 79  ? 338.479 377.766 447.267 1.00 115.67 ? 79  GLY C N   1 
ATOM 5878 C CA  . GLY E 5 79  ? 339.699 377.351 446.609 1.00 115.67 ? 79  GLY C CA  1 
ATOM 5879 C C   . GLY E 5 79  ? 340.816 376.986 447.560 1.00 115.67 ? 79  GLY C C   1 
ATOM 5880 O O   . GLY E 5 79  ? 341.582 377.840 448.009 1.00 115.67 ? 79  GLY C O   1 
ATOM 5881 N N   . LYS E 5 80  ? 340.944 375.692 447.824 1.00 102.74 ? 80  LYS C N   1 
ATOM 5882 C CA  . LYS E 5 80  ? 341.991 375.162 448.678 1.00 102.74 ? 80  LYS C CA  1 
ATOM 5883 C C   . LYS E 5 80  ? 342.354 373.793 448.143 1.00 102.74 ? 80  LYS C C   1 
ATOM 5884 O O   . LYS E 5 80  ? 341.559 373.151 447.457 1.00 102.74 ? 80  LYS C O   1 
ATOM 5885 C CB  . LYS E 5 80  ? 341.543 375.066 450.135 1.00 102.74 ? 80  LYS C CB  1 
ATOM 5886 C CG  . LYS E 5 80  ? 341.842 376.292 450.964 1.00 102.74 ? 80  LYS C CG  1 
ATOM 5887 C CD  . LYS E 5 80  ? 340.825 376.447 452.078 1.00 102.74 ? 80  LYS C CD  1 
ATOM 5888 C CE  . LYS E 5 80  ? 340.828 375.252 453.012 1.00 102.74 ? 80  LYS C CE  1 
ATOM 5889 N NZ  . LYS E 5 80  ? 339.874 375.428 454.141 1.00 102.74 ? 80  LYS C NZ  1 
ATOM 5890 N N   . GLN E 5 81  ? 343.564 373.356 448.458 1.00 99.88  ? 81  GLN C N   1 
ATOM 5891 C CA  . GLN E 5 81  ? 344.053 372.073 447.983 1.00 99.88  ? 81  GLN C CA  1 
ATOM 5892 C C   . GLN E 5 81  ? 343.313 370.958 448.705 1.00 99.88  ? 81  GLN C C   1 
ATOM 5893 O O   . GLN E 5 81  ? 343.427 370.818 449.925 1.00 99.88  ? 81  GLN C O   1 
ATOM 5894 C CB  . GLN E 5 81  ? 345.557 371.952 448.194 1.00 99.88  ? 81  GLN C CB  1 
ATOM 5895 C CG  . GLN E 5 81  ? 346.114 370.610 447.789 1.00 99.88  ? 81  GLN C CG  1 
ATOM 5896 C CD  . GLN E 5 81  ? 347.453 370.731 447.102 1.00 99.88  ? 81  GLN C CD  1 
ATOM 5897 O OE1 . GLN E 5 81  ? 347.862 371.822 446.711 1.00 99.88  ? 81  GLN C OE1 1 
ATOM 5898 N NE2 . GLN E 5 81  ? 348.146 369.611 446.953 1.00 99.88  ? 81  GLN C NE2 1 
ATOM 5899 N N   . VAL E 5 82  ? 342.536 370.188 447.952 1.00 94.68  ? 82  VAL C N   1 
ATOM 5900 C CA  . VAL E 5 82  ? 341.850 369.043 448.530 1.00 94.68  ? 82  VAL C CA  1 
ATOM 5901 C C   . VAL E 5 82  ? 342.846 367.955 448.884 1.00 94.68  ? 82  VAL C C   1 
ATOM 5902 O O   . VAL E 5 82  ? 342.922 367.515 450.034 1.00 94.68  ? 82  VAL C O   1 
ATOM 5903 C CB  . VAL E 5 82  ? 340.773 368.529 447.566 1.00 94.68  ? 82  VAL C CB  1 
ATOM 5904 C CG1 . VAL E 5 82  ? 340.106 367.312 448.142 1.00 94.68  ? 82  VAL C CG1 1 
ATOM 5905 C CG2 . VAL E 5 82  ? 339.760 369.610 447.310 1.00 94.68  ? 82  VAL C CG2 1 
ATOM 5906 N N   . PHE E 5 83  ? 343.630 367.514 447.908 1.00 93.00  ? 83  PHE C N   1 
ATOM 5907 C CA  . PHE E 5 83  ? 344.727 366.600 448.167 1.00 93.00  ? 83  PHE C CA  1 
ATOM 5908 C C   . PHE E 5 83  ? 345.807 366.853 447.130 1.00 93.00  ? 83  PHE C C   1 
ATOM 5909 O O   . PHE E 5 83  ? 345.654 367.690 446.238 1.00 93.00  ? 83  PHE C O   1 
ATOM 5910 C CB  . PHE E 5 83  ? 344.254 365.144 448.166 1.00 93.00  ? 83  PHE C CB  1 
ATOM 5911 C CG  . PHE E 5 83  ? 343.908 364.613 446.812 1.00 93.00  ? 83  PHE C CG  1 
ATOM 5912 C CD1 . PHE E 5 83  ? 342.670 364.856 446.261 1.00 93.00  ? 83  PHE C CD1 1 
ATOM 5913 C CD2 . PHE E 5 83  ? 344.806 363.835 446.104 1.00 93.00  ? 83  PHE C CD2 1 
ATOM 5914 C CE1 . PHE E 5 83  ? 342.341 364.353 445.022 1.00 93.00  ? 83  PHE C CE1 1 
ATOM 5915 C CE2 . PHE E 5 83  ? 344.482 363.339 444.862 1.00 93.00  ? 83  PHE C CE2 1 
ATOM 5916 C CZ  . PHE E 5 83  ? 343.251 363.599 444.324 1.00 93.00  ? 83  PHE C CZ  1 
ATOM 5917 N N   . GLY E 5 84  ? 346.899 366.114 447.243 1.00 93.82  ? 84  GLY C N   1 
ATOM 5918 C CA  . GLY E 5 84  ? 347.996 366.254 446.315 1.00 93.82  ? 84  GLY C CA  1 
ATOM 5919 C C   . GLY E 5 84  ? 349.140 365.338 446.675 1.00 93.82  ? 84  GLY C C   1 
ATOM 5920 O O   . GLY E 5 84  ? 349.447 365.158 447.853 1.00 93.82  ? 84  GLY C O   1 
ATOM 5921 N N   . PHE E 5 85  ? 349.780 364.752 445.672 1.00 91.98  ? 85  PHE C N   1 
ATOM 5922 C CA  . PHE E 5 85  ? 350.853 363.842 445.950 1.00 91.98  ? 85  PHE C CA  1 
ATOM 5923 C C   . PHE E 5 85  ? 351.794 363.849 444.762 1.00 91.98  ? 85  PHE C C   1 
ATOM 5924 O O   . PHE E 5 85  ? 351.329 363.963 443.622 1.00 91.98  ? 85  PHE C O   1 
ATOM 5925 C CB  . PHE E 5 85  ? 350.349 362.421 446.219 1.00 91.98  ? 85  PHE C CB  1 
ATOM 5926 C CG  . PHE E 5 85  ? 349.502 361.839 445.124 1.00 91.98  ? 85  PHE C CG  1 
ATOM 5927 C CD1 . PHE E 5 85  ? 348.140 362.048 445.101 1.00 91.98  ? 85  PHE C CD1 1 
ATOM 5928 C CD2 . PHE E 5 85  ? 350.062 361.034 444.151 1.00 91.98  ? 85  PHE C CD2 1 
ATOM 5929 C CE1 . PHE E 5 85  ? 347.363 361.494 444.119 1.00 91.98  ? 85  PHE C CE1 1 
ATOM 5930 C CE2 . PHE E 5 85  ? 349.287 360.483 443.165 1.00 91.98  ? 85  PHE C CE2 1 
ATOM 5931 C CZ  . PHE E 5 85  ? 347.936 360.712 443.151 1.00 91.98  ? 85  PHE C CZ  1 
ATOM 5932 N N   . PRO E 5 86  ? 353.095 363.731 444.979 1.00 90.77  ? 86  PRO C N   1 
ATOM 5933 C CA  . PRO E 5 86  ? 354.029 363.679 443.857 1.00 90.77  ? 86  PRO C CA  1 
ATOM 5934 C C   . PRO E 5 86  ? 354.019 362.304 443.212 1.00 90.77  ? 86  PRO C C   1 
ATOM 5935 O O   . PRO E 5 86  ? 353.343 361.381 443.656 1.00 90.77  ? 86  PRO C O   1 
ATOM 5936 C CB  . PRO E 5 86  ? 355.372 363.969 444.516 1.00 90.77  ? 86  PRO C CB  1 
ATOM 5937 C CG  . PRO E 5 86  ? 355.216 363.413 445.870 1.00 90.77  ? 86  PRO C CG  1 
ATOM 5938 C CD  . PRO E 5 86  ? 353.797 363.673 446.269 1.00 90.77  ? 86  PRO C CD  1 
ATOM 5939 N N   . LEU E 5 87  ? 354.802 362.180 442.145 1.00 95.68  ? 87  LEU C N   1 
ATOM 5940 C CA  . LEU E 5 87  ? 354.935 360.922 441.426 1.00 95.68  ? 87  LEU C CA  1 
ATOM 5941 C C   . LEU E 5 87  ? 356.374 360.431 441.378 1.00 95.68  ? 87  LEU C C   1 
ATOM 5942 O O   . LEU E 5 87  ? 356.825 359.953 440.333 1.00 95.68  ? 87  LEU C O   1 
ATOM 5943 C CB  . LEU E 5 87  ? 354.380 361.058 440.011 1.00 95.68  ? 87  LEU C CB  1 
ATOM 5944 C CG  . LEU E 5 87  ? 352.903 361.408 439.896 1.00 95.68  ? 87  LEU C CG  1 
ATOM 5945 C CD1 . LEU E 5 87  ? 352.475 361.359 438.447 1.00 95.68  ? 87  LEU C CD1 1 
ATOM 5946 C CD2 . LEU E 5 87  ? 352.073 360.461 440.724 1.00 95.68  ? 87  LEU C CD2 1 
ATOM 5947 N N   . GLN E 5 88  ? 357.102 360.543 442.479 1.00 106.99 ? 88  GLN C N   1 
ATOM 5948 C CA  . GLN E 5 88  ? 358.466 360.045 442.545 1.00 106.99 ? 88  GLN C CA  1 
ATOM 5949 C C   . GLN E 5 88  ? 358.462 358.523 442.518 1.00 106.99 ? 88  GLN C C   1 
ATOM 5950 O O   . GLN E 5 88  ? 357.634 357.904 443.200 1.00 106.99 ? 88  GLN C O   1 
ATOM 5951 C CB  . GLN E 5 88  ? 359.149 360.545 443.810 1.00 106.99 ? 88  GLN C CB  1 
ATOM 5952 C CG  . GLN E 5 88  ? 360.650 360.596 443.710 1.00 106.99 ? 88  GLN C CG  1 
ATOM 5953 C CD  . GLN E 5 88  ? 361.112 361.563 442.648 1.00 106.99 ? 88  GLN C CD  1 
ATOM 5954 O OE1 . GLN E 5 88  ? 360.557 362.651 442.503 1.00 106.99 ? 88  GLN C OE1 1 
ATOM 5955 N NE2 . GLN E 5 88  ? 362.129 361.172 441.892 1.00 106.99 ? 88  GLN C NE2 1 
ATOM 5956 N N   . PRO E 5 89  ? 359.338 357.885 441.745 1.00 103.27 ? 89  PRO C N   1 
ATOM 5957 C CA  . PRO E 5 89  ? 359.327 356.418 441.669 1.00 103.27 ? 89  PRO C CA  1 
ATOM 5958 C C   . PRO E 5 89  ? 359.972 355.795 442.897 1.00 103.27 ? 89  PRO C C   1 
ATOM 5959 O O   . PRO E 5 89  ? 361.124 356.083 443.223 1.00 103.27 ? 89  PRO C O   1 
ATOM 5960 C CB  . PRO E 5 89  ? 360.132 356.121 440.399 1.00 103.27 ? 89  PRO C CB  1 
ATOM 5961 C CG  . PRO E 5 89  ? 360.241 357.429 439.680 1.00 103.27 ? 89  PRO C CG  1 
ATOM 5962 C CD  . PRO E 5 89  ? 360.216 358.477 440.728 1.00 103.27 ? 89  PRO C CD  1 
ATOM 5963 N N   . GLY E 5 90  ? 359.211 354.952 443.592 1.00 104.67 ? 90  GLY C N   1 
ATOM 5964 C CA  . GLY E 5 90  ? 359.745 354.071 444.610 1.00 104.67 ? 90  GLY C CA  1 
ATOM 5965 C C   . GLY E 5 90  ? 360.078 354.696 445.948 1.00 104.67 ? 90  GLY C C   1 
ATOM 5966 O O   . GLY E 5 90  ? 360.155 353.967 446.945 1.00 104.67 ? 90  GLY C O   1 
ATOM 5967 N N   . ALA E 5 91  ? 360.273 356.010 446.022 1.00 109.73 ? 91  ALA C N   1 
ATOM 5968 C CA  . ALA E 5 91  ? 360.741 356.645 447.252 1.00 109.73 ? 91  ALA C CA  1 
ATOM 5969 C C   . ALA E 5 91  ? 359.550 356.934 448.162 1.00 109.73 ? 91  ALA C C   1 
ATOM 5970 O O   . ALA E 5 91  ? 359.090 358.071 448.294 1.00 109.73 ? 91  ALA C O   1 
ATOM 5971 C CB  . ALA E 5 91  ? 361.524 357.911 446.933 1.00 109.73 ? 91  ALA C CB  1 
ATOM 5972 N N   . ASN E 5 92  ? 359.042 355.859 448.782 1.00 104.22 ? 92  ASN C N   1 
ATOM 5973 C CA  . ASN E 5 92  ? 358.022 355.843 449.849 1.00 104.22 ? 92  ASN C CA  1 
ATOM 5974 C C   . ASN E 5 92  ? 356.739 356.615 449.502 1.00 104.22 ? 92  ASN C C   1 
ATOM 5975 O O   . ASN E 5 92  ? 355.959 356.968 450.392 1.00 104.22 ? 92  ASN C O   1 
ATOM 5976 C CB  . ASN E 5 92  ? 358.611 356.310 451.197 1.00 104.22 ? 92  ASN C CB  1 
ATOM 5977 C CG  . ASN E 5 92  ? 358.760 357.829 451.322 1.00 104.22 ? 92  ASN C CG  1 
ATOM 5978 O OD1 . ASN E 5 92  ? 357.857 358.521 451.792 1.00 104.22 ? 92  ASN C OD1 1 
ATOM 5979 N ND2 . ASN E 5 92  ? 359.923 358.341 450.946 1.00 104.22 ? 92  ASN C ND2 1 
ATOM 5980 N N   . ASN E 5 93  ? 356.449 356.809 448.218 1.00 101.31 ? 93  ASN C N   1 
ATOM 5981 C CA  . ASN E 5 93  ? 355.279 357.571 447.804 1.00 101.31 ? 93  ASN C CA  1 
ATOM 5982 C C   . ASN E 5 93  ? 354.015 356.737 448.004 1.00 101.31 ? 93  ASN C C   1 
ATOM 5983 O O   . ASN E 5 93  ? 354.053 355.590 448.456 1.00 101.31 ? 93  ASN C O   1 
ATOM 5984 C CB  . ASN E 5 93  ? 355.433 358.030 446.360 1.00 101.31 ? 93  ASN C CB  1 
ATOM 5985 C CG  . ASN E 5 93  ? 355.673 356.885 445.415 1.00 101.31 ? 93  ASN C CG  1 
ATOM 5986 O OD1 . ASN E 5 93  ? 356.322 355.905 445.768 1.00 101.31 ? 93  ASN C OD1 1 
ATOM 5987 N ND2 . ASN E 5 93  ? 355.155 357.000 444.202 1.00 101.31 ? 93  ASN C ND2 1 
ATOM 5988 N N   . VAL E 5 94  ? 352.867 357.309 447.656 1.00 96.74  ? 94  VAL C N   1 
ATOM 5989 C CA  . VAL E 5 94  ? 351.601 356.674 447.981 1.00 96.74  ? 94  VAL C CA  1 
ATOM 5990 C C   . VAL E 5 94  ? 351.232 355.543 447.035 1.00 96.74  ? 94  VAL C C   1 
ATOM 5991 O O   . VAL E 5 94  ? 350.400 354.703 447.391 1.00 96.74  ? 94  VAL C O   1 
ATOM 5992 C CB  . VAL E 5 94  ? 350.483 357.721 447.999 1.00 96.74  ? 94  VAL C CB  1 
ATOM 5993 C CG1 . VAL E 5 94  ? 350.606 358.574 449.233 1.00 96.74  ? 94  VAL C CG1 1 
ATOM 5994 C CG2 . VAL E 5 94  ? 350.579 358.572 446.769 1.00 96.74  ? 94  VAL C CG2 1 
ATOM 5995 N N   . LEU E 5 95  ? 351.828 355.485 445.849 1.00 94.73  ? 95  LEU C N   1 
ATOM 5996 C CA  . LEU E 5 95  ? 351.565 354.407 444.909 1.00 94.73  ? 95  LEU C CA  1 
ATOM 5997 C C   . LEU E 5 95  ? 352.469 353.208 445.122 1.00 94.73  ? 95  LEU C C   1 
ATOM 5998 O O   . LEU E 5 95  ? 352.659 352.416 444.197 1.00 94.73  ? 95  LEU C O   1 
ATOM 5999 C CB  . LEU E 5 95  ? 351.725 354.906 443.478 1.00 94.73  ? 95  LEU C CB  1 
ATOM 6000 C CG  . LEU E 5 95  ? 350.950 356.163 443.130 1.00 94.73  ? 95  LEU C CG  1 
ATOM 6001 C CD1 . LEU E 5 95  ? 351.248 356.559 441.711 1.00 94.73  ? 95  LEU C CD1 1 
ATOM 6002 C CD2 . LEU E 5 95  ? 349.487 355.885 443.296 1.00 94.73  ? 95  LEU C CD2 1 
ATOM 6003 N N   . ASN E 5 96  ? 353.049 353.062 446.306 1.00 95.86  ? 96  ASN C N   1 
ATOM 6004 C CA  . ASN E 5 96  ? 354.087 352.060 446.476 1.00 95.86  ? 96  ASN C CA  1 
ATOM 6005 C C   . ASN E 5 96  ? 353.494 350.700 446.806 1.00 95.86  ? 96  ASN C C   1 
ATOM 6006 O O   . ASN E 5 96  ? 353.901 349.682 446.241 1.00 95.86  ? 96  ASN C O   1 
ATOM 6007 C CB  . ASN E 5 96  ? 355.059 352.504 447.562 1.00 95.86  ? 96  ASN C CB  1 
ATOM 6008 C CG  . ASN E 5 96  ? 356.482 352.167 447.224 1.00 95.86  ? 96  ASN C CG  1 
ATOM 6009 O OD1 . ASN E 5 96  ? 356.753 351.548 446.198 1.00 95.86  ? 96  ASN C OD1 1 
ATOM 6010 N ND2 . ASN E 5 96  ? 357.409 352.586 448.074 1.00 95.86  ? 96  ASN C ND2 1 
ATOM 6011 N N   . ARG E 5 97  ? 352.528 350.662 447.715 1.00 95.29  ? 97  ARG C N   1 
ATOM 6012 C CA  . ARG E 5 97  ? 352.000 349.395 448.198 1.00 95.29  ? 97  ARG C CA  1 
ATOM 6013 C C   . ARG E 5 97  ? 350.731 348.968 447.479 1.00 95.29  ? 97  ARG C C   1 
ATOM 6014 O O   . ARG E 5 97  ? 350.099 347.996 447.897 1.00 95.29  ? 97  ARG C O   1 
ATOM 6015 C CB  . ARG E 5 97  ? 351.727 349.458 449.704 1.00 95.29  ? 97  ARG C CB  1 
ATOM 6016 C CG  . ARG E 5 97  ? 352.872 349.967 450.565 1.00 95.29  ? 97  ARG C CG  1 
ATOM 6017 C CD  . ARG E 5 97  ? 354.209 349.347 450.201 1.00 95.29  ? 97  ARG C CD  1 
ATOM 6018 N NE  . ARG E 5 97  ? 354.262 347.916 450.457 1.00 95.29  ? 97  ARG C NE  1 
ATOM 6019 C CZ  . ARG E 5 97  ? 354.732 347.383 451.576 1.00 95.29  ? 97  ARG C CZ  1 
ATOM 6020 N NH1 . ARG E 5 97  ? 355.182 348.166 452.546 1.00 95.29  ? 97  ARG C NH1 1 
ATOM 6021 N NH2 . ARG E 5 97  ? 354.755 346.067 451.721 1.00 95.29  ? 97  ARG C NH2 1 
ATOM 6022 N N   . THR E 5 98  ? 350.343 349.660 446.416 1.00 92.43  ? 98  THR C N   1 
ATOM 6023 C CA  . THR E 5 98  ? 349.211 349.212 445.629 1.00 92.43  ? 98  THR C CA  1 
ATOM 6024 C C   . THR E 5 98  ? 349.613 348.044 444.737 1.00 92.43  ? 98  THR C C   1 
ATOM 6025 O O   . THR E 5 98  ? 350.758 347.589 444.734 1.00 92.43  ? 98  THR C O   1 
ATOM 6026 C CB  . THR E 5 98  ? 348.667 350.342 444.772 1.00 92.43  ? 98  THR C CB  1 
ATOM 6027 O OG1 . THR E 5 98  ? 347.659 349.820 443.906 1.00 92.43  ? 98  THR C OG1 1 
ATOM 6028 C CG2 . THR E 5 98  ? 349.758 350.916 443.932 1.00 92.43  ? 98  THR C CG2 1 
ATOM 6029 N N   . LEU E 5 99  ? 348.647 347.564 443.955 1.00 90.16  ? 99  LEU C N   1 
ATOM 6030 C CA  . LEU E 5 99  ? 348.889 346.385 443.136 1.00 90.16  ? 99  LEU C CA  1 
ATOM 6031 C C   . LEU E 5 99  ? 349.791 346.677 441.950 1.00 90.16  ? 99  LEU C C   1 
ATOM 6032 O O   . LEU E 5 99  ? 350.538 345.791 441.528 1.00 90.16  ? 99  LEU C O   1 
ATOM 6033 C CB  . LEU E 5 99  ? 347.569 345.799 442.653 1.00 90.16  ? 99  LEU C CB  1 
ATOM 6034 C CG  . LEU E 5 99  ? 347.575 344.382 442.091 1.00 90.16  ? 99  LEU C CG  1 
ATOM 6035 C CD1 . LEU E 5 99  ? 348.475 343.485 442.904 1.00 90.16  ? 99  LEU C CD1 1 
ATOM 6036 C CD2 . LEU E 5 99  ? 346.175 343.836 442.092 1.00 90.16  ? 99  LEU C CD2 1 
ATOM 6037 N N   . LEU E 5 100 ? 349.747 347.890 441.409 1.00 93.45  ? 100 LEU C N   1 
ATOM 6038 C CA  . LEU E 5 100 ? 350.705 348.254 440.375 1.00 93.45  ? 100 LEU C CA  1 
ATOM 6039 C C   . LEU E 5 100 ? 352.103 348.377 440.960 1.00 93.45  ? 100 LEU C C   1 
ATOM 6040 O O   . LEU E 5 100 ? 353.090 347.976 440.335 1.00 93.45  ? 100 LEU C O   1 
ATOM 6041 C CB  . LEU E 5 100 ? 350.286 349.559 439.712 1.00 93.45  ? 100 LEU C CB  1 
ATOM 6042 C CG  . LEU E 5 100 ? 351.234 350.056 438.633 1.00 93.45  ? 100 LEU C CG  1 
ATOM 6043 C CD1 . LEU E 5 100 ? 351.195 349.099 437.474 1.00 93.45  ? 100 LEU C CD1 1 
ATOM 6044 C CD2 . LEU E 5 100 ? 350.857 351.444 438.197 1.00 93.45  ? 100 LEU C CD2 1 
ATOM 6045 N N   . GLY E 5 101 ? 352.203 348.902 442.175 1.00 94.61  ? 101 GLY C N   1 
ATOM 6046 C CA  . GLY E 5 101 ? 353.499 349.122 442.778 1.00 94.61  ? 101 GLY C CA  1 
ATOM 6047 C C   . GLY E 5 101 ? 354.208 347.868 443.223 1.00 94.61  ? 101 GLY C C   1 
ATOM 6048 O O   . GLY E 5 101 ? 355.439 347.823 443.151 1.00 94.61  ? 101 GLY C O   1 
ATOM 6049 N N   . GLU E 5 102 ? 353.477 346.850 443.659 1.00 96.69  ? 102 GLU C N   1 
ATOM 6050 C CA  . GLU E 5 102 ? 354.128 345.656 444.168 1.00 96.69  ? 102 GLU C CA  1 
ATOM 6051 C C   . GLU E 5 102 ? 354.729 344.794 443.073 1.00 96.69  ? 102 GLU C C   1 
ATOM 6052 O O   . GLU E 5 102 ? 355.609 343.979 443.362 1.00 96.69  ? 102 GLU C O   1 
ATOM 6053 C CB  . GLU E 5 102 ? 353.148 344.817 444.989 1.00 96.69  ? 102 GLU C CB  1 
ATOM 6054 C CG  . GLU E 5 102 ? 352.830 345.391 446.364 1.00 96.69  ? 102 GLU C CG  1 
ATOM 6055 C CD  . GLU E 5 102 ? 353.983 345.288 447.353 1.00 96.69  ? 102 GLU C CD  1 
ATOM 6056 O OE1 . GLU E 5 102 ? 354.922 344.500 447.117 1.00 96.69  ? 102 GLU C OE1 1 
ATOM 6057 O OE2 . GLU E 5 102 ? 353.943 345.993 448.385 1.00 96.69  ? 102 GLU C OE2 1 
ATOM 6058 N N   . ILE E 5 103 ? 354.284 344.949 441.831 1.00 90.94  ? 103 ILE C N   1 
ATOM 6059 C CA  . ILE E 5 103 ? 354.943 344.252 440.737 1.00 90.94  ? 103 ILE C CA  1 
ATOM 6060 C C   . ILE E 5 103 ? 356.135 345.050 440.242 1.00 90.94  ? 103 ILE C C   1 
ATOM 6061 O O   . ILE E 5 103 ? 357.213 344.498 440.010 1.00 90.94  ? 103 ILE C O   1 
ATOM 6062 C CB  . ILE E 5 103 ? 353.942 343.970 439.610 1.00 90.94  ? 103 ILE C CB  1 
ATOM 6063 C CG1 . ILE E 5 103 ? 352.762 343.186 440.157 1.00 90.94  ? 103 ILE C CG1 1 
ATOM 6064 C CG2 . ILE E 5 103 ? 354.597 343.191 438.506 1.00 90.94  ? 103 ILE C CG2 1 
ATOM 6065 C CD1 . ILE E 5 103 ? 351.716 342.905 439.128 1.00 90.94  ? 103 ILE C CD1 1 
ATOM 6066 N N   . LEU E 5 104 ? 355.990 346.365 440.130 1.00 93.51  ? 104 LEU C N   1 
ATOM 6067 C CA  . LEU E 5 104 ? 357.057 347.191 439.586 1.00 93.51  ? 104 LEU C CA  1 
ATOM 6068 C C   . LEU E 5 104 ? 358.191 347.448 440.563 1.00 93.51  ? 104 LEU C C   1 
ATOM 6069 O O   . LEU E 5 104 ? 359.079 348.243 440.248 1.00 93.51  ? 104 LEU C O   1 
ATOM 6070 C CB  . LEU E 5 104 ? 356.500 348.524 439.105 1.00 93.51  ? 104 LEU C CB  1 
ATOM 6071 C CG  . LEU E 5 104 ? 355.477 348.438 437.982 1.00 93.51  ? 104 LEU C CG  1 
ATOM 6072 C CD1 . LEU E 5 104 ? 355.263 349.808 437.392 1.00 93.51  ? 104 LEU C CD1 1 
ATOM 6073 C CD2 . LEU E 5 104 ? 355.914 347.463 436.910 1.00 93.51  ? 104 LEU C CD2 1 
ATOM 6074 N N   . ASN E 5 105 ? 358.185 346.831 441.736 1.00 95.89  ? 105 ASN C N   1 
ATOM 6075 C CA  . ASN E 5 105 ? 359.363 346.812 442.580 1.00 95.89  ? 105 ASN C CA  1 
ATOM 6076 C C   . ASN E 5 105 ? 360.205 345.575 442.355 1.00 95.89  ? 105 ASN C C   1 
ATOM 6077 O O   . ASN E 5 105 ? 361.094 345.292 443.159 1.00 95.89  ? 105 ASN C O   1 
ATOM 6078 C CB  . ASN E 5 105 ? 358.970 346.916 444.048 1.00 95.89  ? 105 ASN C CB  1 
ATOM 6079 C CG  . ASN E 5 105 ? 358.607 348.319 444.441 1.00 95.89  ? 105 ASN C CG  1 
ATOM 6080 O OD1 . ASN E 5 105 ? 357.539 348.568 444.991 1.00 95.89  ? 105 ASN C OD1 1 
ATOM 6081 N ND2 . ASN E 5 105 ? 359.490 349.256 444.142 1.00 95.89  ? 105 ASN C ND2 1 
ATOM 6082 N N   . TYR E 5 106 ? 359.941 344.828 441.289 1.00 96.86  ? 106 TYR C N   1 
ATOM 6083 C CA  . TYR E 5 106 ? 360.794 343.710 440.929 1.00 96.86  ? 106 TYR C CA  1 
ATOM 6084 C C   . TYR E 5 106 ? 361.727 344.028 439.776 1.00 96.86  ? 106 TYR C C   1 
ATOM 6085 O O   . TYR E 5 106 ? 362.680 343.278 439.545 1.00 96.86  ? 106 TYR C O   1 
ATOM 6086 C CB  . TYR E 5 106 ? 359.952 342.487 440.572 1.00 96.86  ? 106 TYR C CB  1 
ATOM 6087 C CG  . TYR E 5 106 ? 359.374 341.788 441.775 1.00 96.86  ? 106 TYR C CG  1 
ATOM 6088 C CD1 . TYR E 5 106 ? 360.198 341.255 442.749 1.00 96.86  ? 106 TYR C CD1 1 
ATOM 6089 C CD2 . TYR E 5 106 ? 358.006 341.651 441.930 1.00 96.86  ? 106 TYR C CD2 1 
ATOM 6090 C CE1 . TYR E 5 106 ? 359.676 340.617 443.845 1.00 96.86  ? 106 TYR C CE1 1 
ATOM 6091 C CE2 . TYR E 5 106 ? 357.476 341.013 443.022 1.00 96.86  ? 106 TYR C CE2 1 
ATOM 6092 C CZ  . TYR E 5 106 ? 358.315 340.502 443.974 1.00 96.86  ? 106 TYR C CZ  1 
ATOM 6093 O OH  . TYR E 5 106 ? 357.786 339.867 445.064 1.00 96.86  ? 106 TYR C OH  1 
ATOM 6094 N N   . TYR E 5 107 ? 361.489 345.114 439.057 1.00 98.58  ? 107 TYR C N   1 
ATOM 6095 C CA  . TYR E 5 107 ? 362.293 345.476 437.905 1.00 98.58  ? 107 TYR C CA  1 
ATOM 6096 C C   . TYR E 5 107 ? 362.913 346.846 438.127 1.00 98.58  ? 107 TYR C C   1 
ATOM 6097 O O   . TYR E 5 107 ? 362.569 347.556 439.071 1.00 98.58  ? 107 TYR C O   1 
ATOM 6098 C CB  . TYR E 5 107 ? 361.453 345.475 436.634 1.00 98.58  ? 107 TYR C CB  1 
ATOM 6099 C CG  . TYR E 5 107 ? 360.726 344.176 436.392 1.00 98.58  ? 107 TYR C CG  1 
ATOM 6100 C CD1 . TYR E 5 107 ? 361.342 343.134 435.726 1.00 98.58  ? 107 TYR C CD1 1 
ATOM 6101 C CD2 . TYR E 5 107 ? 359.423 343.997 436.822 1.00 98.58  ? 107 TYR C CD2 1 
ATOM 6102 C CE1 . TYR E 5 107 ? 360.683 341.950 435.499 1.00 98.58  ? 107 TYR C CE1 1 
ATOM 6103 C CE2 . TYR E 5 107 ? 358.759 342.817 436.602 1.00 98.58  ? 107 TYR C CE2 1 
ATOM 6104 C CZ  . TYR E 5 107 ? 359.393 341.800 435.939 1.00 98.58  ? 107 TYR C CZ  1 
ATOM 6105 O OH  . TYR E 5 107 ? 358.733 340.621 435.713 1.00 98.58  ? 107 TYR C OH  1 
ATOM 6106 N N   . THR E 5 108 ? 363.845 347.218 437.251 1.00 101.13 ? 108 THR C N   1 
ATOM 6107 C CA  . THR E 5 108 ? 364.529 348.492 437.398 1.00 101.13 ? 108 THR C CA  1 
ATOM 6108 C C   . THR E 5 108 ? 364.209 349.501 436.309 1.00 101.13 ? 108 THR C C   1 
ATOM 6109 O O   . THR E 5 108 ? 364.376 350.700 436.542 1.00 101.13 ? 108 THR C O   1 
ATOM 6110 C CB  . THR E 5 108 ? 366.049 348.296 437.429 1.00 101.13 ? 108 THR C CB  1 
ATOM 6111 O OG1 . THR E 5 108 ? 366.526 348.113 436.095 1.00 101.13 ? 108 THR C OG1 1 
ATOM 6112 C CG2 . THR E 5 108 ? 366.422 347.091 438.259 1.00 101.13 ? 108 THR C CG2 1 
ATOM 6113 N N   . HIS E 5 109 ? 363.767 349.064 435.134 1.00 101.63 ? 109 HIS C N   1 
ATOM 6114 C CA  . HIS E 5 109 ? 363.445 349.974 434.041 1.00 101.63 ? 109 HIS C CA  1 
ATOM 6115 C C   . HIS E 5 109 ? 362.005 349.748 433.624 1.00 101.63 ? 109 HIS C C   1 
ATOM 6116 O O   . HIS E 5 109 ? 361.631 348.622 433.289 1.00 101.63 ? 109 HIS C O   1 
ATOM 6117 C CB  . HIS E 5 109 ? 364.370 349.754 432.846 1.00 101.63 ? 109 HIS C CB  1 
ATOM 6118 C CG  . HIS E 5 109 ? 365.759 350.268 433.046 1.00 101.63 ? 109 HIS C CG  1 
ATOM 6119 N ND1 . HIS E 5 109 ? 366.743 350.135 432.091 1.00 101.63 ? 109 HIS C ND1 1 
ATOM 6120 C CD2 . HIS E 5 109 ? 366.332 350.912 434.089 1.00 101.63 ? 109 HIS C CD2 1 
ATOM 6121 C CE1 . HIS E 5 109 ? 367.862 350.676 432.536 1.00 101.63 ? 109 HIS C CE1 1 
ATOM 6122 N NE2 . HIS E 5 109 ? 367.640 351.154 433.747 1.00 101.63 ? 109 HIS C NE2 1 
ATOM 6123 N N   . TRP E 5 110 ? 361.206 350.810 433.625 1.00 100.81 ? 110 TRP C N   1 
ATOM 6124 C CA  . TRP E 5 110 ? 359.833 350.733 433.152 1.00 100.81 ? 110 TRP C CA  1 
ATOM 6125 C C   . TRP E 5 110 ? 359.376 352.131 432.777 1.00 100.81 ? 110 TRP C C   1 
ATOM 6126 O O   . TRP E 5 110 ? 359.830 353.120 433.353 1.00 100.81 ? 110 TRP C O   1 
ATOM 6127 C CB  . TRP E 5 110 ? 358.909 350.138 434.208 1.00 100.81 ? 110 TRP C CB  1 
ATOM 6128 C CG  . TRP E 5 110 ? 359.303 350.496 435.580 1.00 100.81 ? 110 TRP C CG  1 
ATOM 6129 C CD1 . TRP E 5 110 ? 360.098 349.781 436.413 1.00 100.81 ? 110 TRP C CD1 1 
ATOM 6130 C CD2 . TRP E 5 110 ? 358.912 351.661 436.298 1.00 100.81 ? 110 TRP C CD2 1 
ATOM 6131 N NE1 . TRP E 5 110 ? 360.234 350.429 437.611 1.00 100.81 ? 110 TRP C NE1 1 
ATOM 6132 C CE2 . TRP E 5 110 ? 359.512 351.589 437.564 1.00 100.81 ? 110 TRP C CE2 1 
ATOM 6133 C CE3 . TRP E 5 110 ? 358.110 352.759 435.994 1.00 100.81 ? 110 TRP C CE3 1 
ATOM 6134 C CZ2 . TRP E 5 110 ? 359.341 352.571 438.522 1.00 100.81 ? 110 TRP C CZ2 1 
ATOM 6135 C CZ3 . TRP E 5 110 ? 357.941 353.732 436.943 1.00 100.81 ? 110 TRP C CZ3 1 
ATOM 6136 C CH2 . TRP E 5 110 ? 358.552 353.634 438.194 1.00 100.81 ? 110 TRP C CH2 1 
ATOM 6137 N N   . SER E 5 111 ? 358.467 352.210 431.809 1.00 105.98 ? 111 SER C N   1 
ATOM 6138 C CA  . SER E 5 111 ? 358.138 353.511 431.247 1.00 105.98 ? 111 SER C CA  1 
ATOM 6139 C C   . SER E 5 111 ? 356.791 353.473 430.551 1.00 105.98 ? 111 SER C C   1 
ATOM 6140 O O   . SER E 5 111 ? 356.683 352.922 429.456 1.00 105.98 ? 111 SER C O   1 
ATOM 6141 C CB  . SER E 5 111 ? 359.202 353.939 430.238 1.00 105.98 ? 111 SER C CB  1 
ATOM 6142 O OG  . SER E 5 111 ? 358.882 353.460 428.946 1.00 105.98 ? 111 SER C OG  1 
ATOM 6143 N N   . GLY E 5 112 ? 355.795 354.129 431.139 1.00 99.84  ? 112 GLY C N   1 
ATOM 6144 C CA  . GLY E 5 112 ? 354.503 354.215 430.483 1.00 99.84  ? 112 GLY C CA  1 
ATOM 6145 C C   . GLY E 5 112 ? 353.509 355.034 431.280 1.00 99.84  ? 112 GLY C C   1 
ATOM 6146 O O   . GLY E 5 112 ? 353.886 355.901 432.066 1.00 99.84  ? 112 GLY C O   1 
ATOM 6147 N N   . SER E 5 113 ? 352.235 354.734 431.062 1.00 97.79  ? 113 SER C N   1 
ATOM 6148 C CA  . SER E 5 113 ? 351.144 355.599 431.471 1.00 97.79  ? 113 SER C CA  1 
ATOM 6149 C C   . SER E 5 113 ? 350.275 354.935 432.531 1.00 97.79  ? 113 SER C C   1 
ATOM 6150 O O   . SER E 5 113 ? 350.358 353.733 432.784 1.00 97.79  ? 113 SER C O   1 
ATOM 6151 C CB  . SER E 5 113 ? 350.303 356.000 430.258 1.00 97.79  ? 113 SER C CB  1 
ATOM 6152 O OG  . SER E 5 113 ? 350.156 354.904 429.379 1.00 97.79  ? 113 SER C OG  1 
ATOM 6153 N N   . ILE E 5 114 ? 349.427 355.753 433.149 1.00 89.84  ? 114 ILE C N   1 
ATOM 6154 C CA  . ILE E 5 114 ? 348.666 355.385 434.335 1.00 89.84  ? 114 ILE C CA  1 
ATOM 6155 C C   . ILE E 5 114 ? 347.274 355.985 434.216 1.00 89.84  ? 114 ILE C C   1 
ATOM 6156 O O   . ILE E 5 114 ? 347.133 357.172 433.909 1.00 89.84  ? 114 ILE C O   1 
ATOM 6157 C CB  . ILE E 5 114 ? 349.367 355.890 435.611 1.00 89.84  ? 114 ILE C CB  1 
ATOM 6158 C CG1 . ILE E 5 114 ? 350.481 354.947 436.018 1.00 89.84  ? 114 ILE C CG1 1 
ATOM 6159 C CG2 . ILE E 5 114 ? 348.404 356.054 436.766 1.00 89.84  ? 114 ILE C CG2 1 
ATOM 6160 C CD1 . ILE E 5 114 ? 351.196 355.395 437.251 1.00 89.84  ? 114 ILE C CD1 1 
ATOM 6161 N N   . LYS E 5 115 ? 346.245 355.173 434.437 1.00 88.70  ? 115 LYS C N   1 
ATOM 6162 C CA  . LYS E 5 115 ? 344.902 355.703 434.597 1.00 88.70  ? 115 LYS C CA  1 
ATOM 6163 C C   . LYS E 5 115 ? 344.615 355.950 436.066 1.00 88.70  ? 115 LYS C C   1 
ATOM 6164 O O   . LYS E 5 115 ? 344.695 355.036 436.887 1.00 88.70  ? 115 LYS C O   1 
ATOM 6165 C CB  . LYS E 5 115 ? 343.868 354.736 434.038 1.00 88.70  ? 115 LYS C CB  1 
ATOM 6166 C CG  . LYS E 5 115 ? 343.961 354.506 432.548 1.00 88.70  ? 115 LYS C CG  1 
ATOM 6167 C CD  . LYS E 5 115 ? 342.591 354.214 431.972 1.00 88.70  ? 115 LYS C CD  1 
ATOM 6168 C CE  . LYS E 5 115 ? 341.908 353.082 432.719 1.00 88.70  ? 115 LYS C CE  1 
ATOM 6169 N NZ  . LYS E 5 115 ? 340.430 353.228 432.696 1.00 88.70  ? 115 LYS C NZ  1 
ATOM 6170 N N   . LEU E 5 116 ? 344.272 357.184 436.395 1.00 84.92  ? 116 LEU C N   1 
ATOM 6171 C CA  . LEU E 5 116 ? 343.914 357.561 437.758 1.00 84.92  ? 116 LEU C CA  1 
ATOM 6172 C C   . LEU E 5 116 ? 342.408 357.766 437.810 1.00 84.92  ? 116 LEU C C   1 
ATOM 6173 O O   . LEU E 5 116 ? 341.928 358.894 437.690 1.00 84.92  ? 116 LEU C O   1 
ATOM 6174 C CB  . LEU E 5 116 ? 344.652 358.816 438.187 1.00 84.92  ? 116 LEU C CB  1 
ATOM 6175 C CG  . LEU E 5 116 ? 345.962 358.607 438.925 1.00 84.92  ? 116 LEU C CG  1 
ATOM 6176 C CD1 . LEU E 5 116 ? 346.798 359.848 438.841 1.00 84.92  ? 116 LEU C CD1 1 
ATOM 6177 C CD2 . LEU E 5 116 ? 345.667 358.290 440.360 1.00 84.92  ? 116 LEU C CD2 1 
ATOM 6178 N N   . THR E 5 117 ? 341.661 356.689 438.001 1.00 87.06  ? 117 THR C N   1 
ATOM 6179 C CA  . THR E 5 117 ? 340.209 356.750 438.033 1.00 87.06  ? 117 THR C CA  1 
ATOM 6180 C C   . THR E 5 117 ? 339.754 357.213 439.406 1.00 87.06  ? 117 THR C C   1 
ATOM 6181 O O   . THR E 5 117 ? 340.104 356.599 440.416 1.00 87.06  ? 117 THR C O   1 
ATOM 6182 C CB  . THR E 5 117 ? 339.602 355.387 437.709 1.00 87.06  ? 117 THR C CB  1 
ATOM 6183 O OG1 . THR E 5 117 ? 339.803 355.096 436.323 1.00 87.06  ? 117 THR C OG1 1 
ATOM 6184 C CG2 . THR E 5 117 ? 338.118 355.374 438.001 1.00 87.06  ? 117 THR C CG2 1 
ATOM 6185 N N   . PHE E 5 118 ? 338.987 358.293 439.443 1.00 82.35  ? 118 PHE C N   1 
ATOM 6186 C CA  . PHE E 5 118 ? 338.437 358.809 440.682 1.00 82.35  ? 118 PHE C CA  1 
ATOM 6187 C C   . PHE E 5 118 ? 336.977 358.416 440.807 1.00 82.35  ? 118 PHE C C   1 
ATOM 6188 O O   . PHE E 5 118 ? 336.350 357.968 439.848 1.00 82.35  ? 118 PHE C O   1 
ATOM 6189 C CB  . PHE E 5 118 ? 338.567 360.325 440.752 1.00 82.35  ? 118 PHE C CB  1 
ATOM 6190 C CG  . PHE E 5 118 ? 339.945 360.784 441.031 1.00 82.35  ? 118 PHE C CG  1 
ATOM 6191 C CD1 . PHE E 5 118 ? 340.534 360.520 442.245 1.00 82.35  ? 118 PHE C CD1 1 
ATOM 6192 C CD2 . PHE E 5 118 ? 340.659 361.471 440.078 1.00 82.35  ? 118 PHE C CD2 1 
ATOM 6193 C CE1 . PHE E 5 118 ? 341.810 360.939 442.507 1.00 82.35  ? 118 PHE C CE1 1 
ATOM 6194 C CE2 . PHE E 5 118 ? 341.935 361.894 440.334 1.00 82.35  ? 118 PHE C CE2 1 
ATOM 6195 C CZ  . PHE E 5 118 ? 342.511 361.626 441.550 1.00 82.35  ? 118 PHE C CZ  1 
ATOM 6196 N N   . MET E 5 119 ? 336.443 358.595 442.010 1.00 90.99  ? 119 MET C N   1 
ATOM 6197 C CA  . MET E 5 119 ? 335.041 358.315 442.270 1.00 90.99  ? 119 MET C CA  1 
ATOM 6198 C C   . MET E 5 119 ? 334.595 359.129 443.468 1.00 90.99  ? 119 MET C C   1 
ATOM 6199 O O   . MET E 5 119 ? 335.242 359.088 444.516 1.00 90.99  ? 119 MET C O   1 
ATOM 6200 C CB  . MET E 5 119 ? 334.806 356.830 442.533 1.00 90.99  ? 119 MET C CB  1 
ATOM 6201 C CG  . MET E 5 119 ? 333.355 356.494 442.776 1.00 90.99  ? 119 MET C CG  1 
ATOM 6202 S SD  . MET E 5 119 ? 332.980 354.757 442.510 1.00 90.99  ? 119 MET C SD  1 
ATOM 6203 C CE  . MET E 5 119 ? 334.113 354.010 443.666 1.00 90.99  ? 119 MET C CE  1 
ATOM 6204 N N   . PHE E 5 120 ? 333.501 359.863 443.308 1.00 88.18  ? 120 PHE C N   1 
ATOM 6205 C CA  . PHE E 5 120 ? 332.926 360.655 444.387 1.00 88.18  ? 120 PHE C CA  1 
ATOM 6206 C C   . PHE E 5 120 ? 331.861 359.821 445.075 1.00 88.18  ? 120 PHE C C   1 
ATOM 6207 O O   . PHE E 5 120 ? 330.824 359.518 444.481 1.00 88.18  ? 120 PHE C O   1 
ATOM 6208 C CB  . PHE E 5 120 ? 332.336 361.950 443.845 1.00 88.18  ? 120 PHE C CB  1 
ATOM 6209 C CG  . PHE E 5 120 ? 331.762 362.852 444.896 1.00 88.18  ? 120 PHE C CG  1 
ATOM 6210 C CD1 . PHE E 5 120 ? 332.568 363.742 445.570 1.00 88.18  ? 120 PHE C CD1 1 
ATOM 6211 C CD2 . PHE E 5 120 ? 330.411 362.842 445.179 1.00 88.18  ? 120 PHE C CD2 1 
ATOM 6212 C CE1 . PHE E 5 120 ? 332.042 364.587 446.522 1.00 88.18  ? 120 PHE C CE1 1 
ATOM 6213 C CE2 . PHE E 5 120 ? 329.883 363.684 446.131 1.00 88.18  ? 120 PHE C CE2 1 
ATOM 6214 C CZ  . PHE E 5 120 ? 330.702 364.557 446.800 1.00 88.18  ? 120 PHE C CZ  1 
ATOM 6215 N N   . CYS E 5 121 ? 332.112 359.444 446.319 1.00 91.91  ? 121 CYS C N   1 
ATOM 6216 C CA  . CYS E 5 121 ? 331.113 358.740 447.114 1.00 91.91  ? 121 CYS C CA  1 
ATOM 6217 C C   . CYS E 5 121 ? 330.505 359.662 448.163 1.00 91.91  ? 121 CYS C C   1 
ATOM 6218 O O   . CYS E 5 121 ? 330.907 359.693 449.319 1.00 91.91  ? 121 CYS C O   1 
ATOM 6219 C CB  . CYS E 5 121 ? 331.718 357.513 447.763 1.00 91.91  ? 121 CYS C CB  1 
ATOM 6220 S SG  . CYS E 5 121 ? 330.439 356.519 448.486 1.00 91.91  ? 121 CYS C SG  1 
ATOM 6221 N N   . GLY E 5 122 ? 329.511 360.417 447.732 1.00 95.08  ? 122 GLY C N   1 
ATOM 6222 C CA  . GLY E 5 122 ? 328.776 361.265 448.640 1.00 95.08  ? 122 GLY C CA  1 
ATOM 6223 C C   . GLY E 5 122 ? 327.301 361.026 448.460 1.00 95.08  ? 122 GLY C C   1 
ATOM 6224 O O   . GLY E 5 122 ? 326.909 359.981 447.938 1.00 95.08  ? 122 GLY C O   1 
ATOM 6225 N N   . SER E 5 123 ? 326.472 361.981 448.866 1.00 93.93  ? 123 SER C N   1 
ATOM 6226 C CA  . SER E 5 123 ? 325.045 361.830 448.661 1.00 93.93  ? 123 SER C CA  1 
ATOM 6227 C C   . SER E 5 123 ? 324.690 362.030 447.194 1.00 93.93  ? 123 SER C C   1 
ATOM 6228 O O   . SER E 5 123 ? 325.513 362.435 446.370 1.00 93.93  ? 123 SER C O   1 
ATOM 6229 C CB  . SER E 5 123 ? 324.269 362.822 449.509 1.00 93.93  ? 123 SER C CB  1 
ATOM 6230 O OG  . SER E 5 123 ? 322.896 362.731 449.194 1.00 93.93  ? 123 SER C OG  1 
ATOM 6231 N N   . ALA E 5 124 ? 323.437 361.744 446.868 1.00 97.07  ? 124 ALA C N   1 
ATOM 6232 C CA  . ALA E 5 124 ? 322.969 361.903 445.503 1.00 97.07  ? 124 ALA C CA  1 
ATOM 6233 C C   . ALA E 5 124 ? 322.347 363.264 445.245 1.00 97.07  ? 124 ALA C C   1 
ATOM 6234 O O   . ALA E 5 124 ? 321.949 363.539 444.110 1.00 97.07  ? 124 ALA C O   1 
ATOM 6235 C CB  . ALA E 5 124 ? 321.960 360.807 445.156 1.00 97.07  ? 124 ALA C CB  1 
ATOM 6236 N N   . MET E 5 125 ? 322.257 364.118 446.260 1.00 96.78  ? 125 MET C N   1 
ATOM 6237 C CA  . MET E 5 125 ? 321.678 365.442 446.106 1.00 96.78  ? 125 MET C CA  1 
ATOM 6238 C C   . MET E 5 125 ? 322.714 366.552 446.098 1.00 96.78  ? 125 MET C C   1 
ATOM 6239 O O   . MET E 5 125 ? 322.368 367.692 445.782 1.00 96.78  ? 125 MET C O   1 
ATOM 6240 C CB  . MET E 5 125 ? 320.673 365.713 447.226 1.00 96.78  ? 125 MET C CB  1 
ATOM 6241 C CG  . MET E 5 125 ? 319.318 365.088 447.009 1.00 96.78  ? 125 MET C CG  1 
ATOM 6242 S SD  . MET E 5 125 ? 318.429 365.872 445.659 1.00 96.78  ? 125 MET C SD  1 
ATOM 6243 C CE  . MET E 5 125 ? 316.762 365.317 445.991 1.00 96.78  ? 125 MET C CE  1 
ATOM 6244 N N   . ALA E 5 126 ? 323.961 366.258 446.438 1.00 94.35  ? 126 ALA C N   1 
ATOM 6245 C CA  . ALA E 5 126 ? 324.983 367.285 446.555 1.00 94.35  ? 126 ALA C CA  1 
ATOM 6246 C C   . ALA E 5 126 ? 325.694 367.483 445.227 1.00 94.35  ? 126 ALA C C   1 
ATOM 6247 O O   . ALA E 5 126 ? 325.947 366.524 444.498 1.00 94.35  ? 126 ALA C O   1 
ATOM 6248 C CB  . ALA E 5 126 ? 325.998 366.911 447.631 1.00 94.35  ? 126 ALA C CB  1 
ATOM 6249 N N   . THR E 5 127 ? 326.005 368.734 444.913 1.00 91.88  ? 127 THR C N   1 
ATOM 6250 C CA  . THR E 5 127 ? 326.758 369.075 443.716 1.00 91.88  ? 127 THR C CA  1 
ATOM 6251 C C   . THR E 5 127 ? 328.050 369.776 444.106 1.00 91.88  ? 127 THR C C   1 
ATOM 6252 O O   . THR E 5 127 ? 328.370 369.941 445.283 1.00 91.88  ? 127 THR C O   1 
ATOM 6253 C CB  . THR E 5 127 ? 325.964 369.979 442.775 1.00 91.88  ? 127 THR C CB  1 
ATOM 6254 O OG1 . THR E 5 127 ? 326.065 371.331 443.232 1.00 91.88  ? 127 THR C OG1 1 
ATOM 6255 C CG2 . THR E 5 127 ? 324.506 369.574 442.717 1.00 91.88  ? 127 THR C CG2 1 
ATOM 6256 N N   . GLY E 5 128 ? 328.775 370.209 443.090 1.00 90.53  ? 128 GLY C N   1 
ATOM 6257 C CA  . GLY E 5 128 ? 330.062 370.841 443.282 1.00 90.53  ? 128 GLY C CA  1 
ATOM 6258 C C   . GLY E 5 128 ? 330.888 370.692 442.026 1.00 90.53  ? 128 GLY C C   1 
ATOM 6259 O O   . GLY E 5 128 ? 330.470 370.074 441.051 1.00 90.53  ? 128 GLY C O   1 
ATOM 6260 N N   . LYS E 5 129 ? 332.080 371.270 442.072 1.00 88.78  ? 129 LYS C N   1 
ATOM 6261 C CA  . LYS E 5 129 ? 332.987 371.181 440.942 1.00 88.78  ? 129 LYS C CA  1 
ATOM 6262 C C   . LYS E 5 129 ? 334.409 371.086 441.462 1.00 88.78  ? 129 LYS C C   1 
ATOM 6263 O O   . LYS E 5 129 ? 334.758 371.748 442.438 1.00 88.78  ? 129 LYS C O   1 
ATOM 6264 C CB  . LYS E 5 129 ? 332.835 372.387 440.018 1.00 88.78  ? 129 LYS C CB  1 
ATOM 6265 C CG  . LYS E 5 129 ? 331.787 372.218 438.945 1.00 88.78  ? 129 LYS C CG  1 
ATOM 6266 C CD  . LYS E 5 129 ? 331.400 373.551 438.357 1.00 88.78  ? 129 LYS C CD  1 
ATOM 6267 C CE  . LYS E 5 129 ? 330.310 373.390 437.329 1.00 88.78  ? 129 LYS C CE  1 
ATOM 6268 N NZ  . LYS E 5 129 ? 330.790 372.604 436.170 1.00 88.78  ? 129 LYS C NZ  1 
ATOM 6269 N N   . PHE E 5 130 ? 335.224 370.268 440.808 1.00 84.06  ? 130 PHE C N   1 
ATOM 6270 C CA  . PHE E 5 130 ? 336.600 370.071 441.227 1.00 84.06  ? 130 PHE C CA  1 
ATOM 6271 C C   . PHE E 5 130 ? 337.530 370.224 440.038 1.00 84.06  ? 130 PHE C C   1 
ATOM 6272 O O   . PHE E 5 130 ? 337.194 369.816 438.925 1.00 84.06  ? 130 PHE C O   1 
ATOM 6273 C CB  . PHE E 5 130 ? 336.807 368.693 441.843 1.00 84.06  ? 130 PHE C CB  1 
ATOM 6274 C CG  . PHE E 5 130 ? 336.100 368.495 443.140 1.00 84.06  ? 130 PHE C CG  1 
ATOM 6275 C CD1 . PHE E 5 130 ? 336.166 369.448 444.131 1.00 84.06  ? 130 PHE C CD1 1 
ATOM 6276 C CD2 . PHE E 5 130 ? 335.393 367.338 443.380 1.00 84.06  ? 130 PHE C CD2 1 
ATOM 6277 C CE1 . PHE E 5 130 ? 335.519 369.257 445.332 1.00 84.06  ? 130 PHE C CE1 1 
ATOM 6278 C CE2 . PHE E 5 130 ? 334.747 367.143 444.577 1.00 84.06  ? 130 PHE C CE2 1 
ATOM 6279 C CZ  . PHE E 5 130 ? 334.811 368.103 445.553 1.00 84.06  ? 130 PHE C CZ  1 
ATOM 6280 N N   . LEU E 5 131 ? 338.697 370.810 440.281 1.00 86.21  ? 131 LEU C N   1 
ATOM 6281 C CA  . LEU E 5 131 ? 339.772 370.841 439.304 1.00 86.21  ? 131 LEU C CA  1 
ATOM 6282 C C   . LEU E 5 131 ? 340.726 369.690 439.559 1.00 86.21  ? 131 LEU C C   1 
ATOM 6283 O O   . LEU E 5 131 ? 341.026 369.358 440.704 1.00 86.21  ? 131 LEU C O   1 
ATOM 6284 C CB  . LEU E 5 131 ? 340.542 372.154 439.376 1.00 86.21  ? 131 LEU C CB  1 
ATOM 6285 C CG  . LEU E 5 131 ? 339.954 373.311 438.588 1.00 86.21  ? 131 LEU C CG  1 
ATOM 6286 C CD1 . LEU E 5 131 ? 340.718 374.578 438.866 1.00 86.21  ? 131 LEU C CD1 1 
ATOM 6287 C CD2 . LEU E 5 131 ? 340.005 372.979 437.126 1.00 86.21  ? 131 LEU C CD2 1 
ATOM 6288 N N   . LEU E 5 132 ? 341.206 369.082 438.484 1.00 83.51  ? 132 LEU C N   1 
ATOM 6289 C CA  . LEU E 5 132 ? 342.177 367.993 438.566 1.00 83.51  ? 132 LEU C CA  1 
ATOM 6290 C C   . LEU E 5 132 ? 343.367 368.407 437.722 1.00 83.51  ? 132 LEU C C   1 
ATOM 6291 O O   . LEU E 5 132 ? 343.451 368.080 436.540 1.00 83.51  ? 132 LEU C O   1 
ATOM 6292 C CB  . LEU E 5 132 ? 341.590 366.688 438.094 1.00 83.51  ? 132 LEU C CB  1 
ATOM 6293 C CG  . LEU E 5 132 ? 340.318 366.224 438.780 1.00 83.51  ? 132 LEU C CG  1 
ATOM 6294 C CD1 . LEU E 5 132 ? 339.883 364.902 438.205 1.00 83.51  ? 132 LEU C CD1 1 
ATOM 6295 C CD2 . LEU E 5 132 ? 340.559 366.099 440.251 1.00 83.51  ? 132 LEU C CD2 1 
ATOM 6296 N N   . ALA E 5 133 ? 344.291 369.129 438.328 1.00 87.94  ? 133 ALA C N   1 
ATOM 6297 C CA  . ALA E 5 133 ? 345.439 369.634 437.602 1.00 87.94  ? 133 ALA C CA  1 
ATOM 6298 C C   . ALA E 5 133 ? 346.578 368.637 437.686 1.00 87.94  ? 133 ALA C C   1 
ATOM 6299 O O   . ALA E 5 133 ? 346.888 368.131 438.766 1.00 87.94  ? 133 ALA C O   1 
ATOM 6300 C CB  . ALA E 5 133 ? 345.883 370.982 438.159 1.00 87.94  ? 133 ALA C CB  1 
ATOM 6301 N N   . TYR E 5 134 ? 347.190 368.355 436.548 1.00 93.86  ? 134 TYR C N   1 
ATOM 6302 C CA  . TYR E 5 134 ? 348.418 367.580 436.480 1.00 93.86  ? 134 TYR C CA  1 
ATOM 6303 C C   . TYR E 5 134 ? 349.569 368.505 436.132 1.00 93.86  ? 134 TYR C C   1 
ATOM 6304 O O   . TYR E 5 134 ? 349.488 369.259 435.160 1.00 93.86  ? 134 TYR C O   1 
ATOM 6305 C CB  . TYR E 5 134 ? 348.318 366.460 435.453 1.00 93.86  ? 134 TYR C CB  1 
ATOM 6306 C CG  . TYR E 5 134 ? 349.661 365.865 435.162 1.00 93.86  ? 134 TYR C CG  1 
ATOM 6307 C CD1 . TYR E 5 134 ? 350.354 365.176 436.137 1.00 93.86  ? 134 TYR C CD1 1 
ATOM 6308 C CD2 . TYR E 5 134 ? 350.237 365.985 433.906 1.00 93.86  ? 134 TYR C CD2 1 
ATOM 6309 C CE1 . TYR E 5 134 ? 351.593 364.641 435.883 1.00 93.86  ? 134 TYR C CE1 1 
ATOM 6310 C CE2 . TYR E 5 134 ? 351.469 365.442 433.637 1.00 93.86  ? 134 TYR C CE2 1 
ATOM 6311 C CZ  . TYR E 5 134 ? 352.138 364.769 434.627 1.00 93.86  ? 134 TYR C CZ  1 
ATOM 6312 O OH  . TYR E 5 134 ? 353.370 364.225 434.365 1.00 93.86  ? 134 TYR C OH  1 
ATOM 6313 N N   . SER E 5 135 ? 350.631 368.443 436.916 1.00 95.55  ? 135 SER C N   1 
ATOM 6314 C CA  . SER E 5 135 ? 351.717 369.289 436.458 1.00 95.55  ? 135 SER C CA  1 
ATOM 6315 C C   . SER E 5 135 ? 352.777 368.461 435.755 1.00 95.55  ? 135 SER C C   1 
ATOM 6316 O O   . SER E 5 135 ? 353.146 367.391 436.240 1.00 95.55  ? 135 SER C O   1 
ATOM 6317 C CB  . SER E 5 135 ? 352.350 370.037 437.625 1.00 95.55  ? 135 SER C CB  1 
ATOM 6318 O OG  . SER E 5 135 ? 351.451 371.008 438.116 1.00 95.55  ? 135 SER C OG  1 
ATOM 6319 N N   . PRO E 5 136 ? 353.264 368.932 434.614 1.00 98.91  ? 136 PRO C N   1 
ATOM 6320 C CA  . PRO E 5 136 ? 354.340 368.233 433.912 1.00 98.91  ? 136 PRO C CA  1 
ATOM 6321 C C   . PRO E 5 136 ? 355.629 368.300 434.709 1.00 98.91  ? 136 PRO C C   1 
ATOM 6322 O O   . PRO E 5 136 ? 355.791 369.191 435.554 1.00 98.91  ? 136 PRO C O   1 
ATOM 6323 C CB  . PRO E 5 136 ? 354.456 369.011 432.591 1.00 98.91  ? 136 PRO C CB  1 
ATOM 6324 C CG  . PRO E 5 136 ? 353.176 369.761 432.465 1.00 98.91  ? 136 PRO C CG  1 
ATOM 6325 C CD  . PRO E 5 136 ? 352.784 370.096 433.856 1.00 98.91  ? 136 PRO C CD  1 
ATOM 6326 N N   . PRO E 5 137 ? 356.561 367.370 434.491 1.00 102.70 ? 137 PRO C N   1 
ATOM 6327 C CA  . PRO E 5 137 ? 357.801 367.384 435.274 1.00 102.70 ? 137 PRO C CA  1 
ATOM 6328 C C   . PRO E 5 137 ? 358.701 368.532 434.848 1.00 102.70 ? 137 PRO C C   1 
ATOM 6329 O O   . PRO E 5 137 ? 358.785 368.871 433.666 1.00 102.70 ? 137 PRO C O   1 
ATOM 6330 C CB  . PRO E 5 137 ? 358.434 366.025 434.965 1.00 102.70 ? 137 PRO C CB  1 
ATOM 6331 C CG  . PRO E 5 137 ? 357.916 365.684 433.628 1.00 102.70 ? 137 PRO C CG  1 
ATOM 6332 C CD  . PRO E 5 137 ? 356.512 366.211 433.584 1.00 102.70 ? 137 PRO C CD  1 
ATOM 6333 N N   . GLY E 5 138 ? 359.359 369.139 435.827 1.00 109.95 ? 138 GLY C N   1 
ATOM 6334 C CA  . GLY E 5 138 ? 360.209 370.281 435.577 1.00 109.95 ? 138 GLY C CA  1 
ATOM 6335 C C   . GLY E 5 138 ? 359.530 371.564 435.997 1.00 109.95 ? 138 GLY C C   1 
ATOM 6336 O O   . GLY E 5 138 ? 360.153 372.434 436.610 1.00 109.95 ? 138 GLY C O   1 
ATOM 6337 N N   . ALA E 5 139 ? 358.246 371.685 435.683 1.00 109.37 ? 139 ALA C N   1 
ATOM 6338 C CA  . ALA E 5 139 ? 357.470 372.820 436.147 1.00 109.37 ? 139 ALA C CA  1 
ATOM 6339 C C   . ALA E 5 139 ? 357.176 372.669 437.631 1.00 109.37 ? 139 ALA C C   1 
ATOM 6340 O O   . ALA E 5 139 ? 357.121 371.558 438.164 1.00 109.37 ? 139 ALA C O   1 
ATOM 6341 C CB  . ALA E 5 139 ? 356.166 372.944 435.362 1.00 109.37 ? 139 ALA C CB  1 
ATOM 6342 N N   . GLY E 5 140 ? 356.998 373.800 438.299 1.00 106.63 ? 140 GLY C N   1 
ATOM 6343 C CA  . GLY E 5 140 ? 356.791 373.785 439.729 1.00 106.63 ? 140 GLY C CA  1 
ATOM 6344 C C   . GLY E 5 140 ? 355.407 373.321 440.113 1.00 106.63 ? 140 GLY C C   1 
ATOM 6345 O O   . GLY E 5 140 ? 354.511 373.176 439.284 1.00 106.63 ? 140 GLY C O   1 
ATOM 6346 N N   . VAL E 5 141 ? 355.244 373.061 441.401 1.00 105.01 ? 141 VAL C N   1 
ATOM 6347 C CA  . VAL E 5 141 ? 353.914 372.750 441.931 1.00 105.01 ? 141 VAL C CA  1 
ATOM 6348 C C   . VAL E 5 141 ? 353.072 374.021 441.941 1.00 105.01 ? 141 VAL C C   1 
ATOM 6349 O O   . VAL E 5 141 ? 353.587 375.098 442.286 1.00 105.01 ? 141 VAL C O   1 
ATOM 6350 C CB  . VAL E 5 141 ? 354.036 372.121 443.327 1.00 105.01 ? 141 VAL C CB  1 
ATOM 6351 C CG1 . VAL E 5 141 ? 354.893 372.968 444.263 1.00 105.01 ? 141 VAL C CG1 1 
ATOM 6352 C CG2 . VAL E 5 141 ? 352.673 371.878 443.947 1.00 105.01 ? 141 VAL C CG2 1 
ATOM 6353 N N   . PRO E 5 142 ? 351.823 373.984 441.479 1.00 103.06 ? 142 PRO C N   1 
ATOM 6354 C CA  . PRO E 5 142 ? 351.006 375.200 441.509 1.00 103.06 ? 142 PRO C CA  1 
ATOM 6355 C C   . PRO E 5 142 ? 350.566 375.506 442.929 1.00 103.06 ? 142 PRO C C   1 
ATOM 6356 O O   . PRO E 5 142 ? 350.073 374.635 443.646 1.00 103.06 ? 142 PRO C O   1 
ATOM 6357 C CB  . PRO E 5 142 ? 349.819 374.859 440.606 1.00 103.06 ? 142 PRO C CB  1 
ATOM 6358 C CG  . PRO E 5 142 ? 349.752 373.387 440.613 1.00 103.06 ? 142 PRO C CG  1 
ATOM 6359 C CD  . PRO E 5 142 ? 351.149 372.887 440.771 1.00 103.06 ? 142 PRO C CD  1 
ATOM 6360 N N   . LYS E 5 143 ? 350.775 376.749 443.339 1.00 102.78 ? 143 LYS C N   1 
ATOM 6361 C CA  . LYS E 5 143 ? 350.424 377.197 444.674 1.00 102.78 ? 143 LYS C CA  1 
ATOM 6362 C C   . LYS E 5 143 ? 349.164 378.038 444.681 1.00 102.78 ? 143 LYS C C   1 
ATOM 6363 O O   . LYS E 5 143 ? 348.935 378.789 445.632 1.00 102.78 ? 143 LYS C O   1 
ATOM 6364 C CB  . LYS E 5 143 ? 351.581 377.986 445.274 1.00 102.78 ? 143 LYS C CB  1 
ATOM 6365 C CG  . LYS E 5 143 ? 352.075 379.093 444.377 1.00 102.78 ? 143 LYS C CG  1 
ATOM 6366 C CD  . LYS E 5 143 ? 353.438 379.566 444.824 1.00 102.78 ? 143 LYS C CD  1 
ATOM 6367 C CE  . LYS E 5 143 ? 354.490 378.497 444.594 1.00 102.78 ? 143 LYS C CE  1 
ATOM 6368 N NZ  . LYS E 5 143 ? 354.705 378.230 443.147 1.00 102.78 ? 143 LYS C NZ  1 
ATOM 6369 N N   . ASN E 5 144 ? 348.344 377.930 443.646 1.00 102.11 ? 144 ASN C N   1 
ATOM 6370 C CA  . ASN E 5 144 ? 347.205 378.816 443.496 1.00 102.11 ? 144 ASN C CA  1 
ATOM 6371 C C   . ASN E 5 144 ? 346.180 378.135 442.608 1.00 102.11 ? 144 ASN C C   1 
ATOM 6372 O O   . ASN E 5 144 ? 346.504 377.228 441.841 1.00 102.11 ? 144 ASN C O   1 
ATOM 6373 C CB  . ASN E 5 144 ? 347.636 380.157 442.906 1.00 102.11 ? 144 ASN C CB  1 
ATOM 6374 C CG  . ASN E 5 144 ? 346.638 381.239 443.159 1.00 102.11 ? 144 ASN C CG  1 
ATOM 6375 O OD1 . ASN E 5 144 ? 345.799 381.122 444.049 1.00 102.11 ? 144 ASN C OD1 1 
ATOM 6376 N ND2 . ASN E 5 144 ? 346.711 382.305 442.378 1.00 102.11 ? 144 ASN C ND2 1 
ATOM 6377 N N   . ARG E 5 145 ? 344.932 378.572 442.731 1.00 103.74 ? 145 ARG C N   1 
ATOM 6378 C CA  . ARG E 5 145 ? 343.896 378.020 441.872 1.00 103.74 ? 145 ARG C CA  1 
ATOM 6379 C C   . ARG E 5 145 ? 344.025 378.530 440.447 1.00 103.74 ? 145 ARG C C   1 
ATOM 6380 O O   . ARG E 5 145 ? 343.660 377.823 439.504 1.00 103.74 ? 145 ARG C O   1 
ATOM 6381 C CB  . ARG E 5 145 ? 342.521 378.361 442.432 1.00 103.74 ? 145 ARG C CB  1 
ATOM 6382 C CG  . ARG E 5 145 ? 341.390 377.572 441.824 1.00 103.74 ? 145 ARG C CG  1 
ATOM 6383 C CD  . ARG E 5 145 ? 340.058 378.219 442.128 1.00 103.74 ? 145 ARG C CD  1 
ATOM 6384 N NE  . ARG E 5 145 ? 339.888 379.478 441.417 1.00 103.74 ? 145 ARG C NE  1 
ATOM 6385 C CZ  . ARG E 5 145 ? 339.426 379.575 440.177 1.00 103.74 ? 145 ARG C CZ  1 
ATOM 6386 N NH1 . ARG E 5 145 ? 339.299 380.763 439.609 1.00 103.74 ? 145 ARG C NH1 1 
ATOM 6387 N NH2 . ARG E 5 145 ? 339.091 378.485 439.504 1.00 103.74 ? 145 ARG C NH2 1 
ATOM 6388 N N   . LYS E 5 146 ? 344.562 379.735 440.270 1.00 105.32 ? 146 LYS C N   1 
ATOM 6389 C CA  . LYS E 5 146 ? 344.528 380.374 438.961 1.00 105.32 ? 146 LYS C CA  1 
ATOM 6390 C C   . LYS E 5 146 ? 345.508 379.725 437.998 1.00 105.32 ? 146 LYS C C   1 
ATOM 6391 O O   . LYS E 5 146 ? 345.139 379.365 436.876 1.00 105.32 ? 146 LYS C O   1 
ATOM 6392 C CB  . LYS E 5 146 ? 344.821 381.864 439.091 1.00 105.32 ? 146 LYS C CB  1 
ATOM 6393 C CG  . LYS E 5 146 ? 344.917 382.568 437.760 1.00 105.32 ? 146 LYS C CG  1 
ATOM 6394 C CD  . LYS E 5 146 ? 345.417 383.979 437.925 1.00 105.32 ? 146 LYS C CD  1 
ATOM 6395 C CE  . LYS E 5 146 ? 345.659 384.628 436.581 1.00 105.32 ? 146 LYS C CE  1 
ATOM 6396 N NZ  . LYS E 5 146 ? 346.332 385.942 436.733 1.00 105.32 ? 146 LYS C NZ  1 
ATOM 6397 N N   . ASP E 5 147 ? 346.759 379.560 438.411 1.00 110.51 ? 147 ASP C N   1 
ATOM 6398 C CA  . ASP E 5 147 ? 347.740 378.978 437.509 1.00 110.51 ? 147 ASP C CA  1 
ATOM 6399 C C   . ASP E 5 147 ? 347.548 377.483 437.316 1.00 110.51 ? 147 ASP C C   1 
ATOM 6400 O O   . ASP E 5 147 ? 348.052 376.939 436.330 1.00 110.51 ? 147 ASP C O   1 
ATOM 6401 C CB  . ASP E 5 147 ? 349.156 379.248 438.008 1.00 110.51 ? 147 ASP C CB  1 
ATOM 6402 C CG  . ASP E 5 147 ? 349.376 378.746 439.405 1.00 110.51 ? 147 ASP C CG  1 
ATOM 6403 O OD1 . ASP E 5 147 ? 348.375 378.513 440.108 1.00 110.51 ? 147 ASP C OD1 1 
ATOM 6404 O OD2 . ASP E 5 147 ? 350.548 378.578 439.800 1.00 110.51 ? 147 ASP C OD2 1 
ATOM 6405 N N   . ALA E 5 148 ? 346.836 376.812 438.222 1.00 101.33 ? 148 ALA C N   1 
ATOM 6406 C CA  . ALA E 5 148 ? 346.475 375.422 437.985 1.00 101.33 ? 148 ALA C CA  1 
ATOM 6407 C C   . ALA E 5 148 ? 345.512 375.292 436.821 1.00 101.33 ? 148 ALA C C   1 
ATOM 6408 O O   . ALA E 5 148 ? 345.535 374.286 436.110 1.00 101.33 ? 148 ALA C O   1 
ATOM 6409 C CB  . ALA E 5 148 ? 345.858 374.812 439.239 1.00 101.33 ? 148 ALA C CB  1 
ATOM 6410 N N   . MET E 5 149 ? 344.677 376.302 436.610 1.00 106.28 ? 149 MET C N   1 
ATOM 6411 C CA  . MET E 5 149 ? 343.843 376.361 435.421 1.00 106.28 ? 149 MET C CA  1 
ATOM 6412 C C   . MET E 5 149 ? 344.669 376.631 434.168 1.00 106.28 ? 149 MET C C   1 
ATOM 6413 O O   . MET E 5 149 ? 344.264 376.250 433.064 1.00 106.28 ? 149 MET C O   1 
ATOM 6414 C CB  . MET E 5 149 ? 342.775 377.436 435.619 1.00 106.28 ? 149 MET C CB  1 
ATOM 6415 C CG  . MET E 5 149 ? 341.717 377.516 434.556 1.00 106.28 ? 149 MET C CG  1 
ATOM 6416 S SD  . MET E 5 149 ? 342.051 378.901 433.466 1.00 106.28 ? 149 MET C SD  1 
ATOM 6417 C CE  . MET E 5 149 ? 342.251 380.207 434.668 1.00 106.28 ? 149 MET C CE  1 
ATOM 6418 N N   . LEU E 5 150 ? 345.839 377.251 434.316 1.00 107.08 ? 150 LEU C N   1 
ATOM 6419 C CA  . LEU E 5 150 ? 346.665 377.550 433.154 1.00 107.08 ? 150 LEU C CA  1 
ATOM 6420 C C   . LEU E 5 150 ? 347.397 376.325 432.636 1.00 107.08 ? 150 LEU C C   1 
ATOM 6421 O O   . LEU E 5 150 ? 347.700 376.254 431.442 1.00 107.08 ? 150 LEU C O   1 
ATOM 6422 C CB  . LEU E 5 150 ? 347.668 378.648 433.490 1.00 107.08 ? 150 LEU C CB  1 
ATOM 6423 C CG  . LEU E 5 150 ? 347.061 380.014 433.797 1.00 107.08 ? 150 LEU C CG  1 
ATOM 6424 C CD1 . LEU E 5 150 ? 348.149 381.059 433.882 1.00 107.08 ? 150 LEU C CD1 1 
ATOM 6425 C CD2 . LEU E 5 150 ? 346.039 380.403 432.750 1.00 107.08 ? 150 LEU C CD2 1 
ATOM 6426 N N   . GLY E 5 151 ? 347.686 375.355 433.498 1.00 104.71 ? 151 GLY C N   1 
ATOM 6427 C CA  . GLY E 5 151 ? 348.300 374.120 433.062 1.00 104.71 ? 151 GLY C CA  1 
ATOM 6428 C C   . GLY E 5 151 ? 347.297 373.186 432.418 1.00 104.71 ? 151 GLY C C   1 
ATOM 6429 O O   . GLY E 5 151 ? 346.169 373.552 432.094 1.00 104.71 ? 151 GLY C O   1 
ATOM 6430 N N   . THR E 5 152 ? 347.723 371.945 432.217 1.00 96.24  ? 152 THR C N   1 
ATOM 6431 C CA  . THR E 5 152 ? 346.777 370.938 431.768 1.00 96.24  ? 152 THR C CA  1 
ATOM 6432 C C   . THR E 5 152 ? 345.899 370.502 432.929 1.00 96.24  ? 152 THR C C   1 
ATOM 6433 O O   . THR E 5 152 ? 346.377 370.247 434.036 1.00 96.24  ? 152 THR C O   1 
ATOM 6434 C CB  . THR E 5 152 ? 347.494 369.746 431.139 1.00 96.24  ? 152 THR C CB  1 
ATOM 6435 O OG1 . THR E 5 152 ? 346.562 368.675 430.959 1.00 96.24  ? 152 THR C OG1 1 
ATOM 6436 C CG2 . THR E 5 152 ? 348.663 369.284 431.969 1.00 96.24  ? 152 THR C CG2 1 
ATOM 6437 N N   . HIS E 5 153 ? 344.599 370.450 432.680 1.00 91.74  ? 153 HIS C N   1 
ATOM 6438 C CA  . HIS E 5 153 ? 343.637 370.260 433.751 1.00 91.74  ? 153 HIS C CA  1 
ATOM 6439 C C   . HIS E 5 153 ? 342.343 369.742 433.156 1.00 91.74  ? 153 HIS C C   1 
ATOM 6440 O O   . HIS E 5 153 ? 342.119 369.809 431.948 1.00 91.74  ? 153 HIS C O   1 
ATOM 6441 C CB  . HIS E 5 153 ? 343.381 371.560 434.496 1.00 91.74  ? 153 HIS C CB  1 
ATOM 6442 C CG  . HIS E 5 153 ? 342.626 372.558 433.686 1.00 91.74  ? 153 HIS C CG  1 
ATOM 6443 N ND1 . HIS E 5 153 ? 341.293 372.826 433.889 1.00 91.74  ? 153 HIS C ND1 1 
ATOM 6444 C CD2 . HIS E 5 153 ? 343.012 373.331 432.646 1.00 91.74  ? 153 HIS C CD2 1 
ATOM 6445 C CE1 . HIS E 5 153 ? 340.892 373.737 433.021 1.00 91.74  ? 153 HIS C CE1 1 
ATOM 6446 N NE2 . HIS E 5 153 ? 341.917 374.060 432.254 1.00 91.74  ? 153 HIS C NE2 1 
ATOM 6447 N N   . VAL E 5 154 ? 341.484 369.238 434.033 1.00 84.17  ? 154 VAL C N   1 
ATOM 6448 C CA  . VAL E 5 154 ? 340.161 368.764 433.658 1.00 84.17  ? 154 VAL C CA  1 
ATOM 6449 C C   . VAL E 5 154 ? 339.190 369.112 434.777 1.00 84.17  ? 154 VAL C C   1 
ATOM 6450 O O   . VAL E 5 154 ? 339.426 368.781 435.942 1.00 84.17  ? 154 VAL C O   1 
ATOM 6451 C CB  . VAL E 5 154 ? 340.157 367.258 433.339 1.00 84.17  ? 154 VAL C CB  1 
ATOM 6452 C CG1 . VAL E 5 154 ? 340.924 366.465 434.372 1.00 84.17  ? 154 VAL C CG1 1 
ATOM 6453 C CG2 . VAL E 5 154 ? 338.740 366.743 433.259 1.00 84.17  ? 154 VAL C CG2 1 
ATOM 6454 N N   . ILE E 5 155 ? 338.135 369.829 434.441 1.00 85.48  ? 155 ILE C N   1 
ATOM 6455 C CA  . ILE E 5 155 ? 337.145 370.232 435.425 1.00 85.48  ? 155 ILE C CA  1 
ATOM 6456 C C   . ILE E 5 155 ? 336.145 369.097 435.594 1.00 85.48  ? 155 ILE C C   1 
ATOM 6457 O O   . ILE E 5 155 ? 335.743 368.452 434.620 1.00 85.48  ? 155 ILE C O   1 
ATOM 6458 C CB  . ILE E 5 155 ? 336.476 371.557 435.019 1.00 85.48  ? 155 ILE C CB  1 
ATOM 6459 C CG1 . ILE E 5 155 ? 335.491 372.021 436.085 1.00 85.48  ? 155 ILE C CG1 1 
ATOM 6460 C CG2 . ILE E 5 155 ? 335.860 371.495 433.630 1.00 85.48  ? 155 ILE C CG2 1 
ATOM 6461 C CD1 . ILE E 5 155 ? 335.058 373.438 435.909 1.00 85.48  ? 155 ILE C CD1 1 
ATOM 6462 N N   . TRP E 5 156 ? 335.809 368.793 436.838 1.00 91.17  ? 156 TRP C N   1 
ATOM 6463 C CA  . TRP E 5 156 ? 335.041 367.604 437.176 1.00 91.17  ? 156 TRP C CA  1 
ATOM 6464 C C   . TRP E 5 156 ? 333.741 368.029 437.830 1.00 91.17  ? 156 TRP C C   1 
ATOM 6465 O O   . TRP E 5 156 ? 333.738 368.465 438.983 1.00 91.17  ? 156 TRP C O   1 
ATOM 6466 C CB  . TRP E 5 156 ? 335.842 366.705 438.107 1.00 91.17  ? 156 TRP C CB  1 
ATOM 6467 C CG  . TRP E 5 156 ? 335.156 365.455 438.499 1.00 91.17  ? 156 TRP C CG  1 
ATOM 6468 C CD1 . TRP E 5 156 ? 334.239 364.765 437.779 1.00 91.17  ? 156 TRP C CD1 1 
ATOM 6469 C CD2 . TRP E 5 156 ? 335.351 364.725 439.707 1.00 91.17  ? 156 TRP C CD2 1 
ATOM 6470 N NE1 . TRP E 5 156 ? 333.839 363.650 438.468 1.00 91.17  ? 156 TRP C NE1 1 
ATOM 6471 C CE2 . TRP E 5 156 ? 334.510 363.607 439.658 1.00 91.17  ? 156 TRP C CE2 1 
ATOM 6472 C CE3 . TRP E 5 156 ? 336.155 364.913 440.830 1.00 91.17  ? 156 TRP C CE3 1 
ATOM 6473 C CZ2 . TRP E 5 156 ? 334.449 362.683 440.684 1.00 91.17  ? 156 TRP C CZ2 1 
ATOM 6474 C CZ3 . TRP E 5 156 ? 336.093 363.996 441.844 1.00 91.17  ? 156 TRP C CZ3 1 
ATOM 6475 C CH2 . TRP E 5 156 ? 335.248 362.894 441.767 1.00 91.17  ? 156 TRP C CH2 1 
ATOM 6476 N N   . ASP E 5 157 ? 332.642 367.889 437.105 1.00 96.12  ? 157 ASP C N   1 
ATOM 6477 C CA  . ASP E 5 157 ? 331.326 368.138 437.665 1.00 96.12  ? 157 ASP C CA  1 
ATOM 6478 C C   . ASP E 5 157 ? 330.949 366.964 438.549 1.00 96.12  ? 157 ASP C C   1 
ATOM 6479 O O   . ASP E 5 157 ? 331.367 365.835 438.294 1.00 96.12  ? 157 ASP C O   1 
ATOM 6480 C CB  . ASP E 5 157 ? 330.292 368.325 436.561 1.00 96.12  ? 157 ASP C CB  1 
ATOM 6481 C CG  . ASP E 5 157 ? 328.964 368.807 437.091 1.00 96.12  ? 157 ASP C CG  1 
ATOM 6482 O OD1 . ASP E 5 157 ? 328.199 367.980 437.632 1.00 96.12  ? 157 ASP C OD1 1 
ATOM 6483 O OD2 . ASP E 5 157 ? 328.688 370.019 436.978 1.00 96.12  ? 157 ASP C OD2 1 
ATOM 6484 N N   . VAL E 5 158 ? 330.165 367.228 439.588 1.00 92.27  ? 158 VAL C N   1 
ATOM 6485 C CA  . VAL E 5 158 ? 329.773 366.141 440.468 1.00 92.27  ? 158 VAL C CA  1 
ATOM 6486 C C   . VAL E 5 158 ? 328.343 365.709 440.185 1.00 92.27  ? 158 VAL C C   1 
ATOM 6487 O O   . VAL E 5 158 ? 328.022 364.518 440.256 1.00 92.27  ? 158 VAL C O   1 
ATOM 6488 C CB  . VAL E 5 158 ? 329.970 366.574 441.925 1.00 92.27  ? 158 VAL C CB  1 
ATOM 6489 C CG1 . VAL E 5 158 ? 329.621 365.468 442.873 1.00 92.27  ? 158 VAL C CG1 1 
ATOM 6490 C CG2 . VAL E 5 158 ? 331.390 366.986 442.137 1.00 92.27  ? 158 VAL C CG2 1 
ATOM 6491 N N   . GLY E 5 159 ? 327.470 366.650 439.829 1.00 99.61  ? 159 GLY C N   1 
ATOM 6492 C CA  . GLY E 5 159 ? 326.078 366.307 439.603 1.00 99.61  ? 159 GLY C CA  1 
ATOM 6493 C C   . GLY E 5 159 ? 325.846 365.514 438.335 1.00 99.61  ? 159 GLY C C   1 
ATOM 6494 O O   . GLY E 5 159 ? 324.913 364.711 438.266 1.00 99.61  ? 159 GLY C O   1 
ATOM 6495 N N   . LEU E 5 160 ? 326.685 365.713 437.322 1.00 101.43 ? 160 LEU C N   1 
ATOM 6496 C CA  . LEU E 5 160 ? 326.498 365.005 436.063 1.00 101.43 ? 160 LEU C CA  1 
ATOM 6497 C C   . LEU E 5 160 ? 327.058 363.591 436.133 1.00 101.43 ? 160 LEU C C   1 
ATOM 6498 O O   . LEU E 5 160 ? 326.342 362.614 435.895 1.00 101.43 ? 160 LEU C O   1 
ATOM 6499 C CB  . LEU E 5 160 ? 327.156 365.780 434.925 1.00 101.43 ? 160 LEU C CB  1 
ATOM 6500 C CG  . LEU E 5 160 ? 326.559 367.149 434.636 1.00 101.43 ? 160 LEU C CG  1 
ATOM 6501 C CD1 . LEU E 5 160 ? 327.443 367.909 433.675 1.00 101.43 ? 160 LEU C CD1 1 
ATOM 6502 C CD2 . LEU E 5 160 ? 325.172 366.986 434.065 1.00 101.43 ? 160 LEU C CD2 1 
ATOM 6503 N N   . GLN E 5 161 ? 328.339 363.466 436.446 1.00 101.94 ? 161 GLN C N   1 
ATOM 6504 C CA  . GLN E 5 161 ? 329.013 362.182 436.489 1.00 101.94 ? 161 GLN C CA  1 
ATOM 6505 C C   . GLN E 5 161 ? 329.652 361.990 437.855 1.00 101.94 ? 161 GLN C C   1 
ATOM 6506 O O   . GLN E 5 161 ? 329.781 362.929 438.638 1.00 101.94 ? 161 GLN C O   1 
ATOM 6507 C CB  . GLN E 5 161 ? 330.077 362.091 435.403 1.00 101.94 ? 161 GLN C CB  1 
ATOM 6508 C CG  . GLN E 5 161 ? 331.042 363.246 435.443 1.00 101.94 ? 161 GLN C CG  1 
ATOM 6509 C CD  . GLN E 5 161 ? 331.861 363.349 434.186 1.00 101.94 ? 161 GLN C CD  1 
ATOM 6510 O OE1 . GLN E 5 161 ? 331.539 362.733 433.174 1.00 101.94 ? 161 GLN C OE1 1 
ATOM 6511 N NE2 . GLN E 5 161 ? 332.933 364.128 434.240 1.00 101.94 ? 161 GLN C NE2 1 
ATOM 6512 N N   . SER E 5 162 ? 330.069 360.759 438.132 1.00 100.68 ? 162 SER C N   1 
ATOM 6513 C CA  . SER E 5 162 ? 330.648 360.429 439.427 1.00 100.68 ? 162 SER C CA  1 
ATOM 6514 C C   . SER E 5 162 ? 332.024 359.791 439.301 1.00 100.68 ? 162 SER C C   1 
ATOM 6515 O O   . SER E 5 162 ? 332.517 359.210 440.270 1.00 100.68 ? 162 SER C O   1 
ATOM 6516 C CB  . SER E 5 162 ? 329.711 359.507 440.205 1.00 100.68 ? 162 SER C CB  1 
ATOM 6517 O OG  . SER E 5 162 ? 329.203 358.490 439.364 1.00 100.68 ? 162 SER C OG  1 
ATOM 6518 N N   . SER E 5 163 ? 332.654 359.891 438.133 1.00 98.96  ? 163 SER C N   1 
ATOM 6519 C CA  . SER E 5 163 ? 333.964 359.283 437.914 1.00 98.96  ? 163 SER C CA  1 
ATOM 6520 C C   . SER E 5 163 ? 334.611 359.950 436.715 1.00 98.96  ? 163 SER C C   1 
ATOM 6521 O O   . SER E 5 163 ? 334.097 359.828 435.600 1.00 98.96  ? 163 SER C O   1 
ATOM 6522 C CB  . SER E 5 163 ? 333.830 357.786 437.676 1.00 98.96  ? 163 SER C CB  1 
ATOM 6523 O OG  . SER E 5 163 ? 332.721 357.515 436.844 1.00 98.96  ? 163 SER C OG  1 
ATOM 6524 N N   . CYS E 5 164 ? 335.734 360.632 436.924 1.00 94.27  ? 164 CYS C N   1 
ATOM 6525 C CA  . CYS E 5 164 ? 336.458 361.278 435.836 1.00 94.27  ? 164 CYS C CA  1 
ATOM 6526 C C   . CYS E 5 164 ? 337.853 360.687 435.757 1.00 94.27  ? 164 CYS C C   1 
ATOM 6527 O O   . CYS E 5 164 ? 338.641 360.820 436.696 1.00 94.27  ? 164 CYS C O   1 
ATOM 6528 C CB  . CYS E 5 164 ? 336.530 362.789 436.028 1.00 94.27  ? 164 CYS C CB  1 
ATOM 6529 S SG  . CYS E 5 164 ? 336.715 363.696 434.480 1.00 94.27  ? 164 CYS C SG  1 
ATOM 6530 N N   . VAL E 5 165 ? 338.161 360.069 434.627 1.00 92.28  ? 165 VAL C N   1 
ATOM 6531 C CA  . VAL E 5 165 ? 339.370 359.280 434.445 1.00 92.28  ? 165 VAL C CA  1 
ATOM 6532 C C   . VAL E 5 165 ? 340.454 360.180 433.875 1.00 92.28  ? 165 VAL C C   1 
ATOM 6533 O O   . VAL E 5 165 ? 340.218 360.906 432.904 1.00 92.28  ? 165 VAL C O   1 
ATOM 6534 C CB  . VAL E 5 165 ? 339.092 358.081 433.522 1.00 92.28  ? 165 VAL C CB  1 
ATOM 6535 C CG1 . VAL E 5 165 ? 340.370 357.386 433.111 1.00 92.28  ? 165 VAL C CG1 1 
ATOM 6536 C CG2 . VAL E 5 165 ? 338.151 357.106 434.199 1.00 92.28  ? 165 VAL C CG2 1 
ATOM 6537 N N   . LEU E 5 166 ? 341.641 360.137 434.474 1.00 91.27  ? 166 LEU C N   1 
ATOM 6538 C CA  . LEU E 5 166 ? 342.770 360.950 434.048 1.00 91.27  ? 166 LEU C CA  1 
ATOM 6539 C C   . LEU E 5 166 ? 343.925 360.046 433.641 1.00 91.27  ? 166 LEU C C   1 
ATOM 6540 O O   . LEU E 5 166 ? 344.233 359.079 434.343 1.00 91.27  ? 166 LEU C O   1 
ATOM 6541 C CB  . LEU E 5 166 ? 343.196 361.892 435.170 1.00 91.27  ? 166 LEU C CB  1 
ATOM 6542 C CG  . LEU E 5 166 ? 344.251 362.931 434.833 1.00 91.27  ? 166 LEU C CG  1 
ATOM 6543 C CD1 . LEU E 5 166 ? 343.786 363.771 433.674 1.00 91.27  ? 166 LEU C CD1 1 
ATOM 6544 C CD2 . LEU E 5 166 ? 344.510 363.796 436.035 1.00 91.27  ? 166 LEU C CD2 1 
ATOM 6545 N N   . CYS E 5 167 ? 344.563 360.356 432.514 1.00 98.01  ? 167 CYS C N   1 
ATOM 6546 C CA  . CYS E 5 167 ? 345.703 359.600 432.011 1.00 98.01  ? 167 CYS C CA  1 
ATOM 6547 C C   . CYS E 5 167 ? 346.979 360.418 432.156 1.00 98.01  ? 167 CYS C C   1 
ATOM 6548 O O   . CYS E 5 167 ? 346.985 361.622 431.893 1.00 98.01  ? 167 CYS C O   1 
ATOM 6549 C CB  . CYS E 5 167 ? 345.504 359.220 430.546 1.00 98.01  ? 167 CYS C CB  1 
ATOM 6550 S SG  . CYS E 5 167 ? 343.824 358.736 430.144 1.00 98.01  ? 167 CYS C SG  1 
ATOM 6551 N N   . VAL E 5 168 ? 348.063 359.760 432.556 1.00 92.65  ? 168 VAL C N   1 
ATOM 6552 C CA  . VAL E 5 168 ? 349.301 360.453 432.905 1.00 92.65  ? 168 VAL C CA  1 
ATOM 6553 C C   . VAL E 5 168 ? 350.486 359.501 432.766 1.00 92.65  ? 168 VAL C C   1 
ATOM 6554 O O   . VAL E 5 168 ? 350.415 358.357 433.234 1.00 92.65  ? 168 VAL C O   1 
ATOM 6555 C CB  . VAL E 5 168 ? 349.200 361.054 434.318 1.00 92.65  ? 168 VAL C CB  1 
ATOM 6556 C CG1 . VAL E 5 168 ? 348.572 360.077 435.282 1.00 92.65  ? 168 VAL C CG1 1 
ATOM 6557 C CG2 . VAL E 5 168 ? 350.555 361.437 434.840 1.00 92.65  ? 168 VAL C CG2 1 
ATOM 6558 N N   . PRO E 5 169 ? 351.574 359.905 432.112 1.00 93.99  ? 169 PRO C N   1 
ATOM 6559 C CA  . PRO E 5 169 ? 352.739 359.024 432.005 1.00 93.99  ? 169 PRO C CA  1 
ATOM 6560 C C   . PRO E 5 169 ? 353.553 358.988 433.286 1.00 93.99  ? 169 PRO C C   1 
ATOM 6561 O O   . PRO E 5 169 ? 353.546 359.927 434.083 1.00 93.99  ? 169 PRO C O   1 
ATOM 6562 C CB  . PRO E 5 169 ? 353.544 359.647 430.864 1.00 93.99  ? 169 PRO C CB  1 
ATOM 6563 C CG  . PRO E 5 169 ? 353.187 361.077 430.917 1.00 93.99  ? 169 PRO C CG  1 
ATOM 6564 C CD  . PRO E 5 169 ? 351.740 361.128 431.312 1.00 93.99  ? 169 PRO C CD  1 
ATOM 6565 N N   . TRP E 5 170 ? 354.282 357.889 433.464 1.00 95.60  ? 170 TRP C N   1 
ATOM 6566 C CA  . TRP E 5 170 ? 355.059 357.651 434.672 1.00 95.60  ? 170 TRP C CA  1 
ATOM 6567 C C   . TRP E 5 170 ? 356.350 356.942 434.301 1.00 95.60  ? 170 TRP C C   1 
ATOM 6568 O O   . TRP E 5 170 ? 356.320 355.889 433.658 1.00 95.60  ? 170 TRP C O   1 
ATOM 6569 C CB  . TRP E 5 170 ? 354.257 356.816 435.668 1.00 95.60  ? 170 TRP C CB  1 
ATOM 6570 C CG  . TRP E 5 170 ? 354.670 356.977 437.084 1.00 95.60  ? 170 TRP C CG  1 
ATOM 6571 C CD1 . TRP E 5 170 ? 354.948 358.144 437.722 1.00 95.60  ? 170 TRP C CD1 1 
ATOM 6572 C CD2 . TRP E 5 170 ? 354.768 355.947 438.069 1.00 95.60  ? 170 TRP C CD2 1 
ATOM 6573 N NE1 . TRP E 5 170 ? 355.253 357.903 439.035 1.00 95.60  ? 170 TRP C NE1 1 
ATOM 6574 C CE2 . TRP E 5 170 ? 355.146 356.560 439.273 1.00 95.60  ? 170 TRP C CE2 1 
ATOM 6575 C CE3 . TRP E 5 170 ? 354.595 354.565 438.045 1.00 95.60  ? 170 TRP C CE3 1 
ATOM 6576 C CZ2 . TRP E 5 170 ? 355.350 355.841 440.440 1.00 95.60  ? 170 TRP C CZ2 1 
ATOM 6577 C CZ3 . TRP E 5 170 ? 354.794 353.856 439.204 1.00 95.60  ? 170 TRP C CZ3 1 
ATOM 6578 C CH2 . TRP E 5 170 ? 355.168 354.492 440.384 1.00 95.60  ? 170 TRP C CH2 1 
ATOM 6579 N N   . ILE E 5 171 ? 357.479 357.511 434.715 1.00 98.16  ? 171 ILE C N   1 
ATOM 6580 C CA  . ILE E 5 171 ? 358.791 357.065 434.273 1.00 98.16  ? 171 ILE C CA  1 
ATOM 6581 C C   . ILE E 5 171 ? 359.538 356.508 435.477 1.00 98.16  ? 171 ILE C C   1 
ATOM 6582 O O   . ILE E 5 171 ? 359.148 356.719 436.626 1.00 98.16  ? 171 ILE C O   1 
ATOM 6583 C CB  . ILE E 5 171 ? 359.574 358.221 433.608 1.00 98.16  ? 171 ILE C CB  1 
ATOM 6584 C CG1 . ILE E 5 171 ? 360.484 357.708 432.499 1.00 98.16  ? 171 ILE C CG1 1 
ATOM 6585 C CG2 . ILE E 5 171 ? 360.336 359.058 434.628 1.00 98.16  ? 171 ILE C CG2 1 
ATOM 6586 C CD1 . ILE E 5 171 ? 359.739 357.419 431.239 1.00 98.16  ? 171 ILE C CD1 1 
ATOM 6587 N N   . SER E 5 172 ? 360.609 355.770 435.207 1.00 97.74  ? 172 SER C N   1 
ATOM 6588 C CA  . SER E 5 172 ? 361.432 355.235 436.283 1.00 97.74  ? 172 SER C CA  1 
ATOM 6589 C C   . SER E 5 172 ? 362.281 356.331 436.902 1.00 97.74  ? 172 SER C C   1 
ATOM 6590 O O   . SER E 5 172 ? 363.320 356.700 436.357 1.00 97.74  ? 172 SER C O   1 
ATOM 6591 C CB  . SER E 5 172 ? 362.333 354.117 435.777 1.00 97.74  ? 172 SER C CB  1 
ATOM 6592 O OG  . SER E 5 172 ? 363.558 354.643 435.304 1.00 97.74  ? 172 SER C OG  1 
ATOM 6593 N N   . ALA E 5 186 ? 361.966 367.823 439.824 1.00 100.79 ? 186 ALA C N   1 
ATOM 6594 C CA  . ALA E 5 186 ? 360.566 367.497 440.045 1.00 100.79 ? 186 ALA C CA  1 
ATOM 6595 C C   . ALA E 5 186 ? 360.133 366.371 439.119 1.00 100.79 ? 186 ALA C C   1 
ATOM 6596 O O   . ALA E 5 186 ? 360.814 366.058 438.145 1.00 100.79 ? 186 ALA C O   1 
ATOM 6597 C CB  . ALA E 5 186 ? 359.697 368.722 439.837 1.00 100.79 ? 186 ALA C CB  1 
ATOM 6598 N N   . ALA E 5 187 ? 358.992 365.762 439.433 1.00 100.17 ? 187 ALA C N   1 
ATOM 6599 C CA  . ALA E 5 187 ? 358.483 364.652 438.644 1.00 100.17 ? 187 ALA C CA  1 
ATOM 6600 C C   . ALA E 5 187 ? 357.006 364.768 438.308 1.00 100.17 ? 187 ALA C C   1 
ATOM 6601 O O   . ALA E 5 187 ? 356.529 364.008 437.462 1.00 100.17 ? 187 ALA C O   1 
ATOM 6602 C CB  . ALA E 5 187 ? 358.726 363.325 439.375 1.00 100.17 ? 187 ALA C CB  1 
ATOM 6603 N N   . GLY E 5 188 ? 356.271 365.679 438.932 1.00 93.86  ? 188 GLY C N   1 
ATOM 6604 C CA  . GLY E 5 188 ? 354.863 365.866 438.653 1.00 93.86  ? 188 GLY C CA  1 
ATOM 6605 C C   . GLY E 5 188 ? 354.042 365.924 439.924 1.00 93.86  ? 188 GLY C C   1 
ATOM 6606 O O   . GLY E 5 188 ? 354.430 365.434 440.980 1.00 93.86  ? 188 GLY C O   1 
ATOM 6607 N N   . TYR E 5 189 ? 352.887 366.565 439.798 1.00 96.34  ? 189 TYR C N   1 
ATOM 6608 C CA  . TYR E 5 189 ? 351.934 366.644 440.891 1.00 96.34  ? 189 TYR C CA  1 
ATOM 6609 C C   . TYR E 5 189 ? 350.544 366.446 440.318 1.00 96.34  ? 189 TYR C C   1 
ATOM 6610 O O   . TYR E 5 189 ? 350.259 366.864 439.195 1.00 96.34  ? 189 TYR C O   1 
ATOM 6611 C CB  . TYR E 5 189 ? 352.021 367.981 441.623 1.00 96.34  ? 189 TYR C CB  1 
ATOM 6612 C CG  . TYR E 5 189 ? 353.215 368.108 442.528 1.00 96.34  ? 189 TYR C CG  1 
ATOM 6613 C CD1 . TYR E 5 189 ? 354.442 368.516 442.034 1.00 96.34  ? 189 TYR C CD1 1 
ATOM 6614 C CD2 . TYR E 5 189 ? 353.111 367.838 443.880 1.00 96.34  ? 189 TYR C CD2 1 
ATOM 6615 C CE1 . TYR E 5 189 ? 355.537 368.636 442.857 1.00 96.34  ? 189 TYR C CE1 1 
ATOM 6616 C CE2 . TYR E 5 189 ? 354.200 367.957 444.715 1.00 96.34  ? 189 TYR C CE2 1 
ATOM 6617 C CZ  . TYR E 5 189 ? 355.411 368.357 444.197 1.00 96.34  ? 189 TYR C CZ  1 
ATOM 6618 O OH  . TYR E 5 189 ? 356.503 368.479 445.022 1.00 96.34  ? 189 TYR C OH  1 
ATOM 6619 N N   . VAL E 5 190 ? 349.683 365.784 441.084 1.00 92.08  ? 190 VAL C N   1 
ATOM 6620 C CA  . VAL E 5 190 ? 348.351 365.447 440.597 1.00 92.08  ? 190 VAL C CA  1 
ATOM 6621 C C   . VAL E 5 190 ? 347.366 366.147 441.530 1.00 92.08  ? 190 VAL C C   1 
ATOM 6622 O O   . VAL E 5 190 ? 346.384 365.554 441.987 1.00 92.08  ? 190 VAL C O   1 
ATOM 6623 C CB  . VAL E 5 190 ? 348.130 363.923 440.519 1.00 92.08  ? 190 VAL C CB  1 
ATOM 6624 C CG1 . VAL E 5 190 ? 346.957 363.573 439.589 1.00 92.08  ? 190 VAL C CG1 1 
ATOM 6625 C CG2 . VAL E 5 190 ? 349.379 363.210 440.059 1.00 92.08  ? 190 VAL C CG2 1 
ATOM 6626 N N   . THR E 5 191 ? 347.696 367.379 441.910 1.00 92.88  ? 191 THR C N   1 
ATOM 6627 C CA  . THR E 5 191 ? 346.905 368.148 442.864 1.00 92.88  ? 191 THR C CA  1 
ATOM 6628 C C   . THR E 5 191 ? 345.470 368.374 442.395 1.00 92.88  ? 191 THR C C   1 
ATOM 6629 O O   . THR E 5 191 ? 345.154 368.287 441.208 1.00 92.88  ? 191 THR C O   1 
ATOM 6630 C CB  . THR E 5 191 ? 347.562 369.499 443.114 1.00 92.88  ? 191 THR C CB  1 
ATOM 6631 O OG1 . THR E 5 191 ? 346.698 370.298 443.925 1.00 92.88  ? 191 THR C OG1 1 
ATOM 6632 C CG2 . THR E 5 191 ? 347.814 370.217 441.802 1.00 92.88  ? 191 THR C CG2 1 
ATOM 6633 N N   . CYS E 5 192 ? 344.598 368.669 443.357 1.00 94.56  ? 192 CYS C N   1 
ATOM 6634 C CA  . CYS E 5 192 ? 343.170 368.831 443.134 1.00 94.56  ? 192 CYS C CA  1 
ATOM 6635 C C   . CYS E 5 192 ? 342.632 369.970 443.980 1.00 94.56  ? 192 CYS C C   1 
ATOM 6636 O O   . CYS E 5 192 ? 342.847 370.003 445.192 1.00 94.56  ? 192 CYS C O   1 
ATOM 6637 C CB  . CYS E 5 192 ? 342.422 367.556 443.471 1.00 94.56  ? 192 CYS C CB  1 
ATOM 6638 S SG  . CYS E 5 192 ? 340.644 367.736 443.521 1.00 94.56  ? 192 CYS C SG  1 
ATOM 6639 N N   . TRP E 5 193 ? 341.903 370.883 443.350 1.00 93.02  ? 193 TRP C N   1 
ATOM 6640 C CA  . TRP E 5 193 ? 341.514 372.127 443.992 1.00 93.02  ? 193 TRP C CA  1 
ATOM 6641 C C   . TRP E 5 193 ? 340.004 372.260 444.066 1.00 93.02  ? 193 TRP C C   1 
ATOM 6642 O O   . TRP E 5 193 ? 339.274 371.740 443.222 1.00 93.02  ? 193 TRP C O   1 
ATOM 6643 C CB  . TRP E 5 193 ? 342.076 373.325 443.247 1.00 93.02  ? 193 TRP C CB  1 
ATOM 6644 C CG  . TRP E 5 193 ? 343.539 373.308 443.166 1.00 93.02  ? 193 TRP C CG  1 
ATOM 6645 C CD1 . TRP E 5 193 ? 344.293 372.782 442.173 1.00 93.02  ? 193 TRP C CD1 1 
ATOM 6646 C CD2 . TRP E 5 193 ? 344.445 373.833 444.126 1.00 93.02  ? 193 TRP C CD2 1 
ATOM 6647 N NE1 . TRP E 5 193 ? 345.621 372.951 442.449 1.00 93.02  ? 193 TRP C NE1 1 
ATOM 6648 C CE2 . TRP E 5 193 ? 345.739 373.596 443.648 1.00 93.02  ? 193 TRP C CE2 1 
ATOM 6649 C CE3 . TRP E 5 193 ? 344.287 374.488 445.344 1.00 93.02  ? 193 TRP C CE3 1 
ATOM 6650 C CZ2 . TRP E 5 193 ? 346.868 373.985 444.345 1.00 93.02  ? 193 TRP C CZ2 1 
ATOM 6651 C CZ3 . TRP E 5 193 ? 345.404 374.870 446.035 1.00 93.02  ? 193 TRP C CZ3 1 
ATOM 6652 C CH2 . TRP E 5 193 ? 346.680 374.621 445.535 1.00 93.02  ? 193 TRP C CH2 1 
ATOM 6653 N N   . TYR E 5 194 ? 339.550 372.976 445.089 1.00 91.19  ? 194 TYR C N   1 
ATOM 6654 C CA  . TYR E 5 194 ? 338.146 373.337 445.194 1.00 91.19  ? 194 TYR C CA  1 
ATOM 6655 C C   . TYR E 5 194 ? 337.810 374.373 444.140 1.00 91.19  ? 194 TYR C C   1 
ATOM 6656 O O   . TYR E 5 194 ? 338.444 375.427 444.076 1.00 91.19  ? 194 TYR C O   1 
ATOM 6657 C CB  . TYR E 5 194 ? 337.845 373.918 446.569 1.00 91.19  ? 194 TYR C CB  1 
ATOM 6658 C CG  . TYR E 5 194 ? 337.349 372.944 447.600 1.00 91.19  ? 194 TYR C CG  1 
ATOM 6659 C CD1 . TYR E 5 194 ? 336.177 372.239 447.411 1.00 91.19  ? 194 TYR C CD1 1 
ATOM 6660 C CD2 . TYR E 5 194 ? 338.038 372.766 448.785 1.00 91.19  ? 194 TYR C CD2 1 
ATOM 6661 C CE1 . TYR E 5 194 ? 335.723 371.365 448.363 1.00 91.19  ? 194 TYR C CE1 1 
ATOM 6662 C CE2 . TYR E 5 194 ? 337.593 371.899 449.740 1.00 91.19  ? 194 TYR C CE2 1 
ATOM 6663 C CZ  . TYR E 5 194 ? 336.437 371.203 449.526 1.00 91.19  ? 194 TYR C CZ  1 
ATOM 6664 O OH  . TYR E 5 194 ? 336.002 370.334 450.494 1.00 91.19  ? 194 TYR C OH  1 
ATOM 6665 N N   . GLN E 5 195 ? 336.812 374.086 443.314 1.00 90.60  ? 195 GLN C N   1 
ATOM 6666 C CA  . GLN E 5 195 ? 336.338 375.099 442.382 1.00 90.60  ? 195 GLN C CA  1 
ATOM 6667 C C   . GLN E 5 195 ? 335.161 375.862 442.974 1.00 90.60  ? 195 GLN C C   1 
ATOM 6668 O O   . GLN E 5 195 ? 335.142 377.095 442.962 1.00 90.60  ? 195 GLN C O   1 
ATOM 6669 C CB  . GLN E 5 195 ? 335.962 374.459 441.047 1.00 90.60  ? 195 GLN C CB  1 
ATOM 6670 C CG  . GLN E 5 195 ? 335.113 375.338 440.170 1.00 90.60  ? 195 GLN C CG  1 
ATOM 6671 C CD  . GLN E 5 195 ? 335.902 376.434 439.505 1.00 90.60  ? 195 GLN C CD  1 
ATOM 6672 O OE1 . GLN E 5 195 ? 337.128 376.402 439.470 1.00 90.60  ? 195 GLN C OE1 1 
ATOM 6673 N NE2 . GLN E 5 195 ? 335.199 377.413 438.957 1.00 90.60  ? 195 GLN C NE2 1 
ATOM 6674 N N   . THR E 5 196 ? 334.175 375.141 443.491 1.00 93.37  ? 196 THR C N   1 
ATOM 6675 C CA  . THR E 5 196 ? 333.060 375.724 444.217 1.00 93.37  ? 196 THR C CA  1 
ATOM 6676 C C   . THR E 5 196 ? 332.977 375.080 445.590 1.00 93.37  ? 196 THR C C   1 
ATOM 6677 O O   . THR E 5 196 ? 333.839 374.297 445.988 1.00 93.37  ? 196 THR C O   1 
ATOM 6678 C CB  . THR E 5 196 ? 331.737 375.524 443.479 1.00 93.37  ? 196 THR C CB  1 
ATOM 6679 O OG1 . THR E 5 196 ? 331.531 374.126 443.259 1.00 93.37  ? 196 THR C OG1 1 
ATOM 6680 C CG2 . THR E 5 196 ? 331.758 376.238 442.151 1.00 93.37  ? 196 THR C CG2 1 
ATOM 6681 N N   . ASN E 5 197 ? 331.921 375.415 446.317 1.00 95.90  ? 197 ASN C N   1 
ATOM 6682 C CA  . ASN E 5 197 ? 331.619 374.719 447.553 1.00 95.90  ? 197 ASN C CA  1 
ATOM 6683 C C   . ASN E 5 197 ? 330.815 373.464 447.244 1.00 95.90  ? 197 ASN C C   1 
ATOM 6684 O O   . ASN E 5 197 ? 330.719 373.017 446.101 1.00 95.90  ? 197 ASN C O   1 
ATOM 6685 C CB  . ASN E 5 197 ? 330.858 375.626 448.510 1.00 95.90  ? 197 ASN C CB  1 
ATOM 6686 C CG  . ASN E 5 197 ? 331.563 376.931 448.749 1.00 95.90  ? 197 ASN C CG  1 
ATOM 6687 O OD1 . ASN E 5 197 ? 332.772 377.033 448.567 1.00 95.90  ? 197 ASN C OD1 1 
ATOM 6688 N ND2 . ASN E 5 197 ? 330.811 377.943 449.164 1.00 95.90  ? 197 ASN C ND2 1 
ATOM 6689 N N   . ILE E 5 198 ? 330.237 372.873 448.283 1.00 94.17  ? 198 ILE C N   1 
ATOM 6690 C CA  . ILE E 5 198 ? 329.359 371.724 448.127 1.00 94.17  ? 198 ILE C CA  1 
ATOM 6691 C C   . ILE E 5 198 ? 327.946 372.195 448.446 1.00 94.17  ? 198 ILE C C   1 
ATOM 6692 O O   . ILE E 5 198 ? 327.605 372.441 449.600 1.00 94.17  ? 198 ILE C O   1 
ATOM 6693 C CB  . ILE E 5 198 ? 329.784 370.563 449.021 1.00 94.17  ? 198 ILE C CB  1 
ATOM 6694 C CG1 . ILE E 5 198 ? 331.211 370.147 448.691 1.00 94.17  ? 198 ILE C CG1 1 
ATOM 6695 C CG2 . ILE E 5 198 ? 328.851 369.400 448.833 1.00 94.17  ? 198 ILE C CG2 1 
ATOM 6696 C CD1 . ILE E 5 198 ? 331.405 369.770 447.247 1.00 94.17  ? 198 ILE C CD1 1 
ATOM 6697 N N   . VAL E 5 199 ? 327.121 372.324 447.418 1.00 91.22  ? 199 VAL C N   1 
ATOM 6698 C CA  . VAL E 5 199 ? 325.741 372.750 447.603 1.00 91.22  ? 199 VAL C CA  1 
ATOM 6699 C C   . VAL E 5 199 ? 324.895 371.544 447.980 1.00 91.22  ? 199 VAL C C   1 
ATOM 6700 O O   . VAL E 5 199 ? 324.783 370.586 447.209 1.00 91.22  ? 199 VAL C O   1 
ATOM 6701 C CB  . VAL E 5 199 ? 325.210 373.414 446.329 1.00 91.22  ? 199 VAL C CB  1 
ATOM 6702 C CG1 . VAL E 5 199 ? 323.754 373.762 446.495 1.00 91.22  ? 199 VAL C CG1 1 
ATOM 6703 C CG2 . VAL E 5 199 ? 326.026 374.638 446.013 1.00 91.22  ? 199 VAL C CG2 1 
ATOM 6704 N N   . VAL E 5 200 ? 324.301 371.581 449.167 1.00 92.00  ? 200 VAL C N   1 
ATOM 6705 C CA  . VAL E 5 200 ? 323.472 370.475 449.635 1.00 92.00  ? 200 VAL C CA  1 
ATOM 6706 C C   . VAL E 5 200 ? 322.084 371.003 449.971 1.00 92.00  ? 200 VAL C C   1 
ATOM 6707 O O   . VAL E 5 200 ? 321.926 372.198 450.249 1.00 92.00  ? 200 VAL C O   1 
ATOM 6708 C CB  . VAL E 5 200 ? 324.095 369.776 450.854 1.00 92.00  ? 200 VAL C CB  1 
ATOM 6709 C CG1 . VAL E 5 200 ? 325.453 369.203 450.512 1.00 92.00  ? 200 VAL C CG1 1 
ATOM 6710 C CG2 . VAL E 5 200 ? 324.209 370.728 452.028 1.00 92.00  ? 200 VAL C CG2 1 
ATOM 6711 N N   . PRO E 5 201 ? 321.058 370.179 449.926 1.00 92.12  ? 201 PRO C N   1 
ATOM 6712 C CA  . PRO E 5 201 ? 319.780 370.583 450.512 1.00 92.12  ? 201 PRO C CA  1 
ATOM 6713 C C   . PRO E 5 201 ? 319.800 370.309 451.999 1.00 92.12  ? 201 PRO C C   1 
ATOM 6714 O O   . PRO E 5 201 ? 320.765 369.723 452.494 1.00 92.12  ? 201 PRO C O   1 
ATOM 6715 C CB  . PRO E 5 201 ? 318.758 369.701 449.787 1.00 92.12  ? 201 PRO C CB  1 
ATOM 6716 C CG  . PRO E 5 201 ? 319.508 369.088 448.645 1.00 92.12  ? 201 PRO C CG  1 
ATOM 6717 C CD  . PRO E 5 201 ? 320.912 368.971 449.111 1.00 92.12  ? 201 PRO C CD  1 
ATOM 6718 N N   . ALA E 5 202 ? 318.761 370.715 452.721 1.00 95.57  ? 202 ALA C N   1 
ATOM 6719 C CA  . ALA E 5 202 ? 318.703 370.424 454.144 1.00 95.57  ? 202 ALA C CA  1 
ATOM 6720 C C   . ALA E 5 202 ? 318.415 368.946 454.368 1.00 95.57  ? 202 ALA C C   1 
ATOM 6721 O O   . ALA E 5 202 ? 317.983 368.235 453.459 1.00 95.57  ? 202 ALA C O   1 
ATOM 6722 C CB  . ALA E 5 202 ? 317.642 371.280 454.825 1.00 95.57  ? 202 ALA C CB  1 
ATOM 6723 N N   . ASP E 5 203 ? 318.697 368.492 455.596 1.00 99.17  ? 203 ASP C N   1 
ATOM 6724 C CA  . ASP E 5 203 ? 318.608 367.088 456.024 1.00 99.17  ? 203 ASP C CA  1 
ATOM 6725 C C   . ASP E 5 203 ? 319.504 366.168 455.199 1.00 99.17  ? 203 ASP C C   1 
ATOM 6726 O O   . ASP E 5 203 ? 319.222 364.978 455.065 1.00 99.17  ? 203 ASP C O   1 
ATOM 6727 C CB  . ASP E 5 203 ? 317.165 366.571 456.011 1.00 99.17  ? 203 ASP C CB  1 
ATOM 6728 C CG  . ASP E 5 203 ? 316.250 367.383 456.895 1.00 99.17  ? 203 ASP C CG  1 
ATOM 6729 O OD1 . ASP E 5 203 ? 316.698 367.814 457.976 1.00 99.17  ? 203 ASP C OD1 1 
ATOM 6730 O OD2 . ASP E 5 203 ? 315.082 367.594 456.511 1.00 99.17  ? 203 ASP C OD2 1 
ATOM 6731 N N   . VAL E 5 204 ? 320.589 366.705 454.641 1.00 93.40  ? 204 VAL C N   1 
ATOM 6732 C CA  . VAL E 5 204 ? 321.620 365.929 453.961 1.00 93.40  ? 204 VAL C CA  1 
ATOM 6733 C C   . VAL E 5 204 ? 322.951 366.305 454.589 1.00 93.40  ? 204 VAL C C   1 
ATOM 6734 O O   . VAL E 5 204 ? 323.225 367.489 454.806 1.00 93.40  ? 204 VAL C O   1 
ATOM 6735 C CB  . VAL E 5 204 ? 321.663 366.194 452.442 1.00 93.40  ? 204 VAL C CB  1 
ATOM 6736 C CG1 . VAL E 5 204 ? 322.604 365.232 451.771 1.00 93.40  ? 204 VAL C CG1 1 
ATOM 6737 C CG2 . VAL E 5 204 ? 320.294 366.096 451.819 1.00 93.40  ? 204 VAL C CG2 1 
ATOM 6738 N N   . GLN E 5 205 ? 323.774 365.310 454.896 1.00 99.38  ? 205 GLN C N   1 
ATOM 6739 C CA  . GLN E 5 205 ? 325.087 365.607 455.443 1.00 99.38  ? 205 GLN C CA  1 
ATOM 6740 C C   . GLN E 5 205 ? 326.006 366.143 454.358 1.00 99.38  ? 205 GLN C C   1 
ATOM 6741 O O   . GLN E 5 205 ? 325.741 366.004 453.164 1.00 99.38  ? 205 GLN C O   1 
ATOM 6742 C CB  . GLN E 5 205 ? 325.702 364.370 456.082 1.00 99.38  ? 205 GLN C CB  1 
ATOM 6743 C CG  . GLN E 5 205 ? 325.300 364.203 457.522 1.00 99.38  ? 205 GLN C CG  1 
ATOM 6744 C CD  . GLN E 5 205 ? 325.358 365.505 458.291 1.00 99.38  ? 205 GLN C CD  1 
ATOM 6745 O OE1 . GLN E 5 205 ? 326.421 366.107 458.434 1.00 99.38  ? 205 GLN C OE1 1 
ATOM 6746 N NE2 . GLN E 5 205 ? 324.211 365.953 458.784 1.00 99.38  ? 205 GLN C NE2 1 
ATOM 6747 N N   . SER E 5 206 ? 327.101 366.763 454.788 1.00 100.85 ? 206 SER C N   1 
ATOM 6748 C CA  . SER E 5 206 ? 328.001 367.454 453.877 1.00 100.85 ? 206 SER C CA  1 
ATOM 6749 C C   . SER E 5 206 ? 329.364 366.800 453.730 1.00 100.85 ? 206 SER C C   1 
ATOM 6750 O O   . SER E 5 206 ? 329.977 366.927 452.672 1.00 100.85 ? 206 SER C O   1 
ATOM 6751 C CB  . SER E 5 206 ? 328.196 368.903 454.336 1.00 100.85 ? 206 SER C CB  1 
ATOM 6752 O OG  . SER E 5 206 ? 328.883 368.950 455.571 1.00 100.85 ? 206 SER C OG  1 
ATOM 6753 N N   . SER E 5 207 ? 329.855 366.110 454.753 1.00 104.54 ? 207 SER C N   1 
ATOM 6754 C CA  . SER E 5 207 ? 331.225 365.601 454.755 1.00 104.54 ? 207 SER C CA  1 
ATOM 6755 C C   . SER E 5 207 ? 331.308 364.364 453.875 1.00 104.54 ? 207 SER C C   1 
ATOM 6756 O O   . SER E 5 207 ? 331.335 363.237 454.370 1.00 104.54 ? 207 SER C O   1 
ATOM 6757 C CB  . SER E 5 207 ? 331.670 365.286 456.176 1.00 104.54 ? 207 SER C CB  1 
ATOM 6758 O OG  . SER E 5 207 ? 330.774 364.382 456.796 1.00 104.54 ? 207 SER C OG  1 
ATOM 6759 N N   . CYS E 5 208 ? 331.377 364.568 452.569 1.00 103.99 ? 208 CYS C N   1 
ATOM 6760 C CA  . CYS E 5 208 ? 331.481 363.469 451.624 1.00 103.99 ? 208 CYS C CA  1 
ATOM 6761 C C   . CYS E 5 208 ? 332.941 363.123 451.375 1.00 103.99 ? 208 CYS C C   1 
ATOM 6762 O O   . CYS E 5 208 ? 333.842 363.927 451.613 1.00 103.99 ? 208 CYS C O   1 
ATOM 6763 C CB  . CYS E 5 208 ? 330.794 363.825 450.309 1.00 103.99 ? 208 CYS C CB  1 
ATOM 6764 S SG  . CYS E 5 208 ? 329.211 364.661 450.499 1.00 103.99 ? 208 CYS C SG  1 
ATOM 6765 N N   . ASP E 5 209 ? 333.171 361.896 450.916 1.00 100.24 ? 209 ASP C N   1 
ATOM 6766 C CA  . ASP E 5 209 ? 334.514 361.371 450.734 1.00 100.24 ? 209 ASP C CA  1 
ATOM 6767 C C   . ASP E 5 209 ? 334.777 361.093 449.260 1.00 100.24 ? 209 ASP C C   1 
ATOM 6768 O O   . ASP E 5 209 ? 333.871 361.141 448.427 1.00 100.24 ? 209 ASP C O   1 
ATOM 6769 C CB  . ASP E 5 209 ? 334.727 360.089 451.548 1.00 100.24 ? 209 ASP C CB  1 
ATOM 6770 C CG  . ASP E 5 209 ? 334.686 360.325 453.056 1.00 100.24 ? 209 ASP C CG  1 
ATOM 6771 O OD1 . ASP E 5 209 ? 334.010 361.265 453.516 1.00 100.24 ? 209 ASP C OD1 1 
ATOM 6772 O OD2 . ASP E 5 209 ? 335.327 359.552 453.794 1.00 100.24 ? 209 ASP C OD2 1 
ATOM 6773 N N   . ILE E 5 210 ? 336.036 360.803 448.942 1.00 89.16  ? 210 ILE C N   1 
ATOM 6774 C CA  . ILE E 5 210 ? 336.483 360.579 447.572 1.00 89.16  ? 210 ILE C CA  1 
ATOM 6775 C C   . ILE E 5 210 ? 337.423 359.385 447.563 1.00 89.16  ? 210 ILE C C   1 
ATOM 6776 O O   . ILE E 5 210 ? 338.398 359.358 448.319 1.00 89.16  ? 210 ILE C O   1 
ATOM 6777 C CB  . ILE E 5 210 ? 337.193 361.820 446.996 1.00 89.16  ? 210 ILE C CB  1 
ATOM 6778 C CG1 . ILE E 5 210 ? 336.184 362.898 446.627 1.00 89.16  ? 210 ILE C CG1 1 
ATOM 6779 C CG2 . ILE E 5 210 ? 338.015 361.472 445.772 1.00 89.16  ? 210 ILE C CG2 1 
ATOM 6780 C CD1 . ILE E 5 210 ? 336.815 364.127 446.039 1.00 89.16  ? 210 ILE C CD1 1 
ATOM 6781 N N   . LEU E 5 211 ? 337.138 358.404 446.716 1.00 87.05  ? 211 LEU C N   1 
ATOM 6782 C CA  . LEU E 5 211 ? 338.041 357.286 446.499 1.00 87.05  ? 211 LEU C CA  1 
ATOM 6783 C C   . LEU E 5 211 ? 338.893 357.527 445.262 1.00 87.05  ? 211 LEU C C   1 
ATOM 6784 O O   . LEU E 5 211 ? 338.518 358.278 444.362 1.00 87.05  ? 211 LEU C O   1 
ATOM 6785 C CB  . LEU E 5 211 ? 337.263 355.984 446.345 1.00 87.05  ? 211 LEU C CB  1 
ATOM 6786 C CG  . LEU E 5 211 ? 336.464 355.557 447.565 1.00 87.05  ? 211 LEU C CG  1 
ATOM 6787 C CD1 . LEU E 5 211 ? 335.834 354.213 447.314 1.00 87.05  ? 211 LEU C CD1 1 
ATOM 6788 C CD2 . LEU E 5 211 ? 337.361 355.502 448.771 1.00 87.05  ? 211 LEU C CD2 1 
ATOM 6789 N N   . CYS E 5 212 ? 340.047 356.867 445.222 1.00 87.79  ? 212 CYS C N   1 
ATOM 6790 C CA  . CYS E 5 212 ? 340.979 357.010 444.115 1.00 87.79  ? 212 CYS C CA  1 
ATOM 6791 C C   . CYS E 5 212 ? 341.504 355.649 443.695 1.00 87.79  ? 212 CYS C C   1 
ATOM 6792 O O   . CYS E 5 212 ? 341.802 354.807 444.543 1.00 87.79  ? 212 CYS C O   1 
ATOM 6793 C CB  . CYS E 5 212 ? 342.152 357.901 444.490 1.00 87.79  ? 212 CYS C CB  1 
ATOM 6794 S SG  . CYS E 5 212 ? 343.554 357.717 443.392 1.00 87.79  ? 212 CYS C SG  1 
ATOM 6795 N N   . PHE E 5 213 ? 341.640 355.444 442.392 1.00 85.56  ? 213 PHE C N   1 
ATOM 6796 C CA  . PHE E 5 213 ? 342.131 354.185 441.862 1.00 85.56  ? 213 PHE C CA  1 
ATOM 6797 C C   . PHE E 5 213 ? 343.319 354.417 440.946 1.00 85.56  ? 213 PHE C C   1 
ATOM 6798 O O   . PHE E 5 213 ? 343.504 355.500 440.392 1.00 85.56  ? 213 PHE C O   1 
ATOM 6799 C CB  . PHE E 5 213 ? 341.052 353.446 441.088 1.00 85.56  ? 213 PHE C CB  1 
ATOM 6800 C CG  . PHE E 5 213 ? 339.834 353.183 441.880 1.00 85.56  ? 213 PHE C CG  1 
ATOM 6801 C CD1 . PHE E 5 213 ? 339.811 352.174 442.808 1.00 85.56  ? 213 PHE C CD1 1 
ATOM 6802 C CD2 . PHE E 5 213 ? 338.716 353.962 441.714 1.00 85.56  ? 213 PHE C CD2 1 
ATOM 6803 C CE1 . PHE E 5 213 ? 338.688 351.937 443.544 1.00 85.56  ? 213 PHE C CE1 1 
ATOM 6804 C CE2 . PHE E 5 213 ? 337.587 353.726 442.446 1.00 85.56  ? 213 PHE C CE2 1 
ATOM 6805 C CZ  . PHE E 5 213 ? 337.574 352.714 443.362 1.00 85.56  ? 213 PHE C CZ  1 
ATOM 6806 N N   . VAL E 5 214 ? 344.114 353.366 440.778 1.00 87.00  ? 214 VAL C N   1 
ATOM 6807 C CA  . VAL E 5 214 ? 345.295 353.409 439.931 1.00 87.00  ? 214 VAL C CA  1 
ATOM 6808 C C   . VAL E 5 214 ? 345.304 352.134 439.104 1.00 87.00  ? 214 VAL C C   1 
ATOM 6809 O O   . VAL E 5 214 ? 344.754 351.106 439.507 1.00 87.00  ? 214 VAL C O   1 
ATOM 6810 C CB  . VAL E 5 214 ? 346.576 353.595 440.780 1.00 87.00  ? 214 VAL C CB  1 
ATOM 6811 C CG1 . VAL E 5 214 ? 346.915 352.344 441.551 1.00 87.00  ? 214 VAL C CG1 1 
ATOM 6812 C CG2 . VAL E 5 214 ? 347.749 354.044 439.932 1.00 87.00  ? 214 VAL C CG2 1 
ATOM 6813 N N   . SER E 5 215 ? 345.872 352.218 437.912 1.00 90.11  ? 215 SER C N   1 
ATOM 6814 C CA  . SER E 5 215 ? 345.814 351.112 436.976 1.00 90.11  ? 215 SER C CA  1 
ATOM 6815 C C   . SER E 5 215 ? 347.028 351.180 436.070 1.00 90.11  ? 215 SER C C   1 
ATOM 6816 O O   . SER E 5 215 ? 347.955 351.961 436.297 1.00 90.11  ? 215 SER C O   1 
ATOM 6817 C CB  . SER E 5 215 ? 344.531 351.158 436.153 1.00 90.11  ? 215 SER C CB  1 
ATOM 6818 O OG  . SER E 5 215 ? 344.669 350.410 434.961 1.00 90.11  ? 215 SER C OG  1 
ATOM 6819 N N   . ALA E 5 216 ? 347.022 350.350 435.041 1.00 100.65 ? 216 ALA C N   1 
ATOM 6820 C CA  . ALA E 5 216 ? 347.983 350.427 433.960 1.00 100.65 ? 216 ALA C CA  1 
ATOM 6821 C C   . ALA E 5 216 ? 347.221 350.703 432.679 1.00 100.65 ? 216 ALA C C   1 
ATOM 6822 O O   . ALA E 5 216 ? 346.101 350.216 432.501 1.00 100.65 ? 216 ALA C O   1 
ATOM 6823 C CB  . ALA E 5 216 ? 348.769 349.132 433.831 1.00 100.65 ? 216 ALA C CB  1 
ATOM 6824 N N   . CYS E 5 217 ? 347.821 351.475 431.784 1.00 110.12 ? 217 CYS C N   1 
ATOM 6825 C CA  . CYS E 5 217 ? 347.173 351.777 430.520 1.00 110.12 ? 217 CYS C CA  1 
ATOM 6826 C C   . CYS E 5 217 ? 347.626 350.835 429.418 1.00 110.12 ? 217 CYS C C   1 
ATOM 6827 O O   . CYS E 5 217 ? 347.634 351.224 428.246 1.00 110.12 ? 217 CYS C O   1 
ATOM 6828 C CB  . CYS E 5 217 ? 347.432 353.231 430.129 1.00 110.12 ? 217 CYS C CB  1 
ATOM 6829 S SG  . CYS E 5 217 ? 346.122 353.982 429.139 1.00 110.12 ? 217 CYS C SG  1 
ATOM 6830 N N   . ASN E 5 218 ? 347.948 349.589 429.776 1.00 119.02 ? 218 ASN C N   1 
ATOM 6831 C CA  . ASN E 5 218 ? 348.446 348.450 428.990 1.00 119.02 ? 218 ASN C CA  1 
ATOM 6832 C C   . ASN E 5 218 ? 349.497 348.822 427.951 1.00 119.02 ? 218 ASN C C   1 
ATOM 6833 O O   . ASN E 5 218 ? 349.480 348.248 426.859 1.00 119.02 ? 218 ASN C O   1 
ATOM 6834 C CB  . ASN E 5 218 ? 347.356 347.613 428.282 1.00 119.02 ? 218 ASN C CB  1 
ATOM 6835 C CG  . ASN E 5 218 ? 346.256 348.441 427.619 1.00 119.02 ? 218 ASN C CG  1 
ATOM 6836 O OD1 . ASN E 5 218 ? 345.460 349.106 428.283 1.00 119.02 ? 218 ASN C OD1 1 
ATOM 6837 N ND2 . ASN E 5 218 ? 346.211 348.394 426.293 1.00 119.02 ? 218 ASN C ND2 1 
ATOM 6838 N N   . ASP E 5 219 ? 350.402 349.748 428.236 1.00 120.20 ? 219 ASP C N   1 
ATOM 6839 C CA  . ASP E 5 219 ? 351.385 350.163 427.248 1.00 120.20 ? 219 ASP C CA  1 
ATOM 6840 C C   . ASP E 5 219 ? 352.750 350.455 427.864 1.00 120.20 ? 219 ASP C C   1 
ATOM 6841 O O   . ASP E 5 219 ? 353.370 351.476 427.559 1.00 120.20 ? 219 ASP C O   1 
ATOM 6842 C CB  . ASP E 5 219 ? 350.877 351.376 426.476 1.00 120.20 ? 219 ASP C CB  1 
ATOM 6843 C CG  . ASP E 5 219 ? 350.353 352.464 427.384 1.00 120.20 ? 219 ASP C CG  1 
ATOM 6844 O OD1 . ASP E 5 219 ? 350.317 352.251 428.613 1.00 120.20 ? 219 ASP C OD1 1 
ATOM 6845 O OD2 . ASP E 5 219 ? 349.969 353.533 426.871 1.00 120.20 ? 219 ASP C OD2 1 
ATOM 6846 N N   . PHE E 5 220 ? 353.250 349.581 428.738 1.00 114.86 ? 220 PHE C N   1 
ATOM 6847 C CA  . PHE E 5 220 ? 354.613 349.729 429.230 1.00 114.86 ? 220 PHE C CA  1 
ATOM 6848 C C   . PHE E 5 220 ? 355.253 348.388 429.536 1.00 114.86 ? 220 PHE C C   1 
ATOM 6849 O O   . PHE E 5 220 ? 354.584 347.445 429.963 1.00 114.86 ? 220 PHE C O   1 
ATOM 6850 C CB  . PHE E 5 220 ? 354.686 350.631 430.462 1.00 114.86 ? 220 PHE C CB  1 
ATOM 6851 C CG  . PHE E 5 220 ? 354.102 350.064 431.705 1.00 114.86 ? 220 PHE C CG  1 
ATOM 6852 C CD1 . PHE E 5 220 ? 352.753 350.162 431.944 1.00 114.86 ? 220 PHE C CD1 1 
ATOM 6853 C CD2 . PHE E 5 220 ? 354.917 349.545 432.689 1.00 114.86 ? 220 PHE C CD2 1 
ATOM 6854 C CE1 . PHE E 5 220 ? 352.225 349.679 433.108 1.00 114.86 ? 220 PHE C CE1 1 
ATOM 6855 C CE2 . PHE E 5 220 ? 354.391 349.062 433.853 1.00 114.86 ? 220 PHE C CE2 1 
ATOM 6856 C CZ  . PHE E 5 220 ? 353.045 349.130 434.061 1.00 114.86 ? 220 PHE C CZ  1 
ATOM 6857 N N   . SER E 5 221 ? 356.564 348.341 429.352 1.00 112.95 ? 221 SER C N   1 
ATOM 6858 C CA  . SER E 5 221 ? 357.359 347.134 429.468 1.00 112.95 ? 221 SER C CA  1 
ATOM 6859 C C   . SER E 5 221 ? 358.381 347.280 430.584 1.00 112.95 ? 221 SER C C   1 
ATOM 6860 O O   . SER E 5 221 ? 358.742 348.388 430.985 1.00 112.95 ? 221 SER C O   1 
ATOM 6861 C CB  . SER E 5 221 ? 358.070 346.841 428.150 1.00 112.95 ? 221 SER C CB  1 
ATOM 6862 O OG  . SER E 5 221 ? 358.623 348.033 427.622 1.00 112.95 ? 221 SER C OG  1 
ATOM 6863 N N   . VAL E 5 222 ? 358.848 346.139 431.086 1.00 105.48 ? 222 VAL C N   1 
ATOM 6864 C CA  . VAL E 5 222 ? 359.824 346.113 432.163 1.00 105.48 ? 222 VAL C CA  1 
ATOM 6865 C C   . VAL E 5 222 ? 361.039 345.308 431.730 1.00 105.48 ? 222 VAL C C   1 
ATOM 6866 O O   . VAL E 5 222 ? 360.951 344.394 430.909 1.00 105.48 ? 222 VAL C O   1 
ATOM 6867 C CB  . VAL E 5 222 ? 359.235 345.547 433.468 1.00 105.48 ? 222 VAL C CB  1 
ATOM 6868 C CG1 . VAL E 5 222 ? 358.162 346.462 433.995 1.00 105.48 ? 222 VAL C CG1 1 
ATOM 6869 C CG2 . VAL E 5 222 ? 358.660 344.175 433.234 1.00 105.48 ? 222 VAL C CG2 1 
ATOM 6870 N N   . ARG E 5 223 ? 362.199 345.697 432.263 1.00 104.00 ? 223 ARG C N   1 
ATOM 6871 C CA  . ARG E 5 223 ? 363.462 345.018 432.000 1.00 104.00 ? 223 ARG C CA  1 
ATOM 6872 C C   . ARG E 5 223 ? 364.210 344.853 433.314 1.00 104.00 ? 223 ARG C C   1 
ATOM 6873 O O   . ARG E 5 223 ? 363.905 345.523 434.302 1.00 104.00 ? 223 ARG C O   1 
ATOM 6874 C CB  . ARG E 5 223 ? 364.341 345.786 430.999 1.00 104.00 ? 223 ARG C CB  1 
ATOM 6875 C CG  . ARG E 5 223 ? 363.614 346.475 429.845 1.00 104.00 ? 223 ARG C CG  1 
ATOM 6876 C CD  . ARG E 5 223 ? 364.561 347.187 428.897 1.00 104.00 ? 223 ARG C CD  1 
ATOM 6877 N NE  . ARG E 5 223 ? 365.243 346.258 428.008 1.00 104.00 ? 223 ARG C NE  1 
ATOM 6878 C CZ  . ARG E 5 223 ? 366.541 345.993 428.069 1.00 104.00 ? 223 ARG C CZ  1 
ATOM 6879 N NH1 . ARG E 5 223 ? 367.296 346.590 428.979 1.00 104.00 ? 223 ARG C NH1 1 
ATOM 6880 N NH2 . ARG E 5 223 ? 367.086 345.132 427.221 1.00 104.00 ? 223 ARG C NH2 1 
ATOM 6881 N N   . MET E 5 224 ? 365.200 343.950 433.299 1.00 104.74 ? 224 MET C N   1 
ATOM 6882 C CA  . MET E 5 224 ? 366.224 343.798 434.341 1.00 104.74 ? 224 MET C CA  1 
ATOM 6883 C C   . MET E 5 224 ? 365.616 343.453 435.704 1.00 104.74 ? 224 MET C C   1 
ATOM 6884 O O   . MET E 5 224 ? 365.541 344.286 436.607 1.00 104.74 ? 224 MET C O   1 
ATOM 6885 C CB  . MET E 5 224 ? 367.101 345.052 434.438 1.00 104.74 ? 224 MET C CB  1 
ATOM 6886 C CG  . MET E 5 224 ? 368.435 344.830 435.128 1.00 104.74 ? 224 MET C CG  1 
ATOM 6887 S SD  . MET E 5 224 ? 369.517 343.766 434.167 1.00 104.74 ? 224 MET C SD  1 
ATOM 6888 C CE  . MET E 5 224 ? 369.503 344.615 432.592 1.00 104.74 ? 224 MET C CE  1 
ATOM 6889 N N   . LEU E 5 225 ? 365.122 342.219 435.793 1.00 98.98  ? 225 LEU C N   1 
ATOM 6890 C CA  . LEU E 5 225 ? 364.519 341.703 437.020 1.00 98.98  ? 225 LEU C CA  1 
ATOM 6891 C C   . LEU E 5 225 ? 365.482 341.757 438.202 1.00 98.98  ? 225 LEU C C   1 
ATOM 6892 O O   . LEU E 5 225 ? 366.697 341.638 438.042 1.00 98.98  ? 225 LEU C O   1 
ATOM 6893 C CB  . LEU E 5 225 ? 364.063 340.262 436.802 1.00 98.98  ? 225 LEU C CB  1 
ATOM 6894 C CG  . LEU E 5 225 ? 363.086 339.630 437.793 1.00 98.98  ? 225 LEU C CG  1 
ATOM 6895 C CD1 . LEU E 5 225 ? 362.092 338.790 437.035 1.00 98.98  ? 225 LEU C CD1 1 
ATOM 6896 C CD2 . LEU E 5 225 ? 363.794 338.777 438.827 1.00 98.98  ? 225 LEU C CD2 1 
ATOM 6897 N N   . LYS E 5 226 ? 364.922 341.950 439.396 1.00 100.19 ? 226 LYS C N   1 
ATOM 6898 C CA  . LYS E 5 226 ? 365.664 341.890 440.646 1.00 100.19 ? 226 LYS C CA  1 
ATOM 6899 C C   . LYS E 5 226 ? 364.725 341.385 441.734 1.00 100.19 ? 226 LYS C C   1 
ATOM 6900 O O   . LYS E 5 226 ? 363.625 340.906 441.451 1.00 100.19 ? 226 LYS C O   1 
ATOM 6901 C CB  . LYS E 5 226 ? 366.268 343.253 441.001 1.00 100.19 ? 226 LYS C CB  1 
ATOM 6902 C CG  . LYS E 5 226 ? 365.276 344.345 441.357 1.00 100.19 ? 226 LYS C CG  1 
ATOM 6903 C CD  . LYS E 5 226 ? 365.936 345.340 442.292 1.00 100.19 ? 226 LYS C CD  1 
ATOM 6904 C CE  . LYS E 5 226 ? 365.033 346.508 442.596 1.00 100.19 ? 226 LYS C CE  1 
ATOM 6905 N NZ  . LYS E 5 226 ? 363.741 346.061 443.163 1.00 100.19 ? 226 LYS C NZ  1 
ATOM 6906 N N   . ASP E 5 227 ? 365.162 341.467 442.985 1.00 105.12 ? 227 ASP C N   1 
ATOM 6907 C CA  . ASP E 5 227 ? 364.287 341.139 444.099 1.00 105.12 ? 227 ASP C CA  1 
ATOM 6908 C C   . ASP E 5 227 ? 363.714 342.406 444.725 1.00 105.12 ? 227 ASP C C   1 
ATOM 6909 O O   . ASP E 5 227 ? 364.195 343.516 444.494 1.00 105.12 ? 227 ASP C O   1 
ATOM 6910 C CB  . ASP E 5 227 ? 365.028 340.335 445.160 1.00 105.12 ? 227 ASP C CB  1 
ATOM 6911 C CG  . ASP E 5 227 ? 366.253 341.050 445.676 1.00 105.12 ? 227 ASP C CG  1 
ATOM 6912 O OD1 . ASP E 5 227 ? 366.739 341.976 444.997 1.00 105.12 ? 227 ASP C OD1 1 
ATOM 6913 O OD2 . ASP E 5 227 ? 366.722 340.700 446.778 1.00 105.12 ? 227 ASP C OD2 1 
ATOM 6914 N N   . THR E 5 228 ? 362.702 342.225 445.526 1.00 100.74 ? 228 THR C N   1 
ATOM 6915 C CA  . THR E 5 228 ? 362.019 343.305 446.216 1.00 100.74 ? 228 THR C CA  1 
ATOM 6916 C C   . THR E 5 228 ? 362.768 343.689 447.486 1.00 100.74 ? 228 THR C C   1 
ATOM 6917 O O   . THR E 5 228 ? 363.507 342.876 448.047 1.00 100.74 ? 228 THR C O   1 
ATOM 6918 C CB  . THR E 5 228 ? 360.593 342.887 446.562 1.00 100.74 ? 228 THR C CB  1 
ATOM 6919 O OG1 . THR E 5 228 ? 359.953 343.909 447.332 1.00 100.74 ? 228 THR C OG1 1 
ATOM 6920 C CG2 . THR E 5 228 ? 360.588 341.588 447.342 1.00 100.74 ? 228 THR C CG2 1 
ATOM 6921 N N   . PRO E 5 229 ? 362.648 344.931 447.946 1.00 100.24 ? 229 PRO C N   1 
ATOM 6922 C CA  . PRO E 5 229 ? 363.189 345.300 449.260 1.00 100.24 ? 229 PRO C CA  1 
ATOM 6923 C C   . PRO E 5 229 ? 362.198 345.226 450.413 1.00 100.24 ? 229 PRO C C   1 
ATOM 6924 O O   . PRO E 5 229 ? 362.546 345.657 451.515 1.00 100.24 ? 229 PRO C O   1 
ATOM 6925 C CB  . PRO E 5 229 ? 363.622 346.750 449.030 1.00 100.24 ? 229 PRO C CB  1 
ATOM 6926 C CG  . PRO E 5 229 ? 362.631 347.258 448.083 1.00 100.24 ? 229 PRO C CG  1 
ATOM 6927 C CD  . PRO E 5 229 ? 362.337 346.124 447.143 1.00 100.24 ? 229 PRO C CD  1 
ATOM 6928 N N   . PHE E 5 230 ? 360.990 344.711 450.206 1.00 101.23 ? 230 PHE C N   1 
ATOM 6929 C CA  . PHE E 5 230 ? 359.990 344.653 451.273 1.00 101.23 ? 230 PHE C CA  1 
ATOM 6930 C C   . PHE E 5 230 ? 360.014 343.318 452.008 1.00 101.23 ? 230 PHE C C   1 
ATOM 6931 O O   . PHE E 5 230 ? 358.986 342.666 452.179 1.00 101.23 ? 230 PHE C O   1 
ATOM 6932 C CB  . PHE E 5 230 ? 358.610 344.927 450.698 1.00 101.23 ? 230 PHE C CB  1 
ATOM 6933 C CG  . PHE E 5 230 ? 358.537 346.180 449.896 1.00 101.23 ? 230 PHE C CG  1 
ATOM 6934 C CD1 . PHE E 5 230 ? 359.085 347.357 450.376 1.00 101.23 ? 230 PHE C CD1 1 
ATOM 6935 C CD2 . PHE E 5 230 ? 357.934 346.181 448.652 1.00 101.23 ? 230 PHE C CD2 1 
ATOM 6936 C CE1 . PHE E 5 230 ? 359.024 348.517 449.630 1.00 101.23 ? 230 PHE C CE1 1 
ATOM 6937 C CE2 . PHE E 5 230 ? 357.869 347.336 447.902 1.00 101.23 ? 230 PHE C CE2 1 
ATOM 6938 C CZ  . PHE E 5 230 ? 358.416 348.505 448.390 1.00 101.23 ? 230 PHE C CZ  1 
ATOM 6939 N N   . ILE E 5 231 ? 361.196 342.913 452.467 1.00 101.74 ? 231 ILE C N   1 
ATOM 6940 C CA  . ILE E 5 231 ? 361.388 341.651 453.167 1.00 101.74 ? 231 ILE C CA  1 
ATOM 6941 C C   . ILE E 5 231 ? 362.678 341.755 453.973 1.00 101.74 ? 231 ILE C C   1 
ATOM 6942 O O   . ILE E 5 231 ? 363.507 342.637 453.742 1.00 101.74 ? 231 ILE C O   1 
ATOM 6943 C CB  . ILE E 5 231 ? 361.414 340.453 452.189 1.00 101.74 ? 231 ILE C CB  1 
ATOM 6944 C CG1 . ILE E 5 231 ? 360.780 339.230 452.841 1.00 101.74 ? 231 ILE C CG1 1 
ATOM 6945 C CG2 . ILE E 5 231 ? 362.822 340.165 451.675 1.00 101.74 ? 231 ILE C CG2 1 
ATOM 6946 C CD1 . ILE E 5 231 ? 359.317 339.427 453.141 1.00 101.74 ? 231 ILE C CD1 1 
ATOM 6947 N N   . ARG E 5 232 ? 362.832 340.871 454.956 1.00 99.79  ? 232 ARG C N   1 
ATOM 6948 C CA  . ARG E 5 232 ? 364.023 340.861 455.798 1.00 99.79  ? 232 ARG C CA  1 
ATOM 6949 C C   . ARG E 5 232 ? 365.259 340.441 455.009 1.00 99.79  ? 232 ARG C C   1 
ATOM 6950 O O   . ARG E 5 232 ? 365.159 339.700 454.033 1.00 99.79  ? 232 ARG C O   1 
ATOM 6951 C CB  . ARG E 5 232 ? 363.826 339.927 456.994 1.00 99.79  ? 232 ARG C CB  1 
ATOM 6952 C CG  . ARG E 5 232 ? 363.492 338.494 456.616 1.00 99.79  ? 232 ARG C CG  1 
ATOM 6953 C CD  . ARG E 5 232 ? 364.648 337.557 456.908 1.00 99.79  ? 232 ARG C CD  1 
ATOM 6954 N NE  . ARG E 5 232 ? 364.373 336.201 456.450 1.00 99.79  ? 232 ARG C NE  1 
ATOM 6955 C CZ  . ARG E 5 232 ? 365.253 335.208 456.492 1.00 99.79  ? 232 ARG C CZ  1 
ATOM 6956 N NH1 . ARG E 5 232 ? 366.465 335.417 456.983 1.00 99.79  ? 232 ARG C NH1 1 
ATOM 6957 N NH2 . ARG E 5 232 ? 364.920 334.004 456.050 1.00 99.79  ? 232 ARG C NH2 1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   LYS 3   3   3   LYS LYS H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  GLN 13  13  13  GLN GLN H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  SER 19  19  19  SER SER H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  ALA 23  23  23  ALA ALA H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  THR 28  28  28  THR THR H . n 
A 1 29  PHE 29  29  29  PHE PHE H . n 
A 1 30  THR 30  30  30  THR THR H . n 
A 1 31  ASP 31  31  31  ASP ASP H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  TYR 33  33  33  TYR TYR H . n 
A 1 34  MET 34  34  34  MET MET H . n 
A 1 35  ASN 35  35  35  ASN ASN H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  PRO 40  40  40  PRO PRO H . n 
A 1 41  SER 41  41  41  SER SER H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  ALA 44  44  44  ALA ALA H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  TRP 47  47  47  TRP TRP H . n 
A 1 48  LEU 48  48  48  LEU LEU H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  PHE 50  50  50  PHE PHE H . n 
A 1 51  LEU 51  51  51  LEU LEU H . n 
A 1 52  ARG 52  52  52  ARG ARG H . n 
A 1 53  ASN 53  53  53  ASN ASN H . n 
A 1 54  LYS 54  54  54  LYS LYS H . n 
A 1 55  ALA 55  55  55  ALA ALA H . n 
A 1 56  ASN 56  56  56  ASN ASN H . n 
A 1 57  GLY 57  57  57  GLY GLY H . n 
A 1 58  TYR 58  58  58  TYR TYR H . n 
A 1 59  THR 59  59  59  THR THR H . n 
A 1 60  THR 60  60  60  THR THR H . n 
A 1 61  GLU 61  61  61  GLU GLU H . n 
A 1 62  TYR 62  62  62  TYR TYR H . n 
A 1 63  SER 63  63  63  SER SER H . n 
A 1 64  ALA 64  64  64  ALA ALA H . n 
A 1 65  SER 65  65  65  SER SER H . n 
A 1 66  VAL 66  66  66  VAL VAL H . n 
A 1 67  LYS 67  67  67  LYS LYS H . n 
A 1 68  GLY 68  68  68  GLY GLY H . n 
A 1 69  ARG 69  69  69  ARG ARG H . n 
A 1 70  PHE 70  70  70  PHE PHE H . n 
A 1 71  THR 71  71  71  THR THR H . n 
A 1 72  ILE 72  72  72  ILE ILE H . n 
A 1 73  SER 73  73  73  SER SER H . n 
A 1 74  ARG 74  74  74  ARG ARG H . n 
A 1 75  ASP 75  75  75  ASP ASP H . n 
A 1 76  ASN 76  76  76  ASN ASN H . n 
A 1 77  SER 77  77  77  SER SER H . n 
A 1 78  GLN 78  78  78  GLN GLN H . n 
A 1 79  SER 79  79  79  SER SER H . n 
A 1 80  ILE 80  80  80  ILE ILE H . n 
A 1 81  LEU 81  81  81  LEU LEU H . n 
A 1 82  TYR 82  82  82  TYR TYR H . n 
A 1 83  LEU 83  83  83  LEU LEU H . n 
A 1 84  GLN 84  84  84  GLN GLN H . n 
A 1 85  MET 85  85  85  MET MET H . n 
A 1 86  ASN 86  86  86  ASN ASN H . n 
A 1 87  ALA 87  87  87  ALA ALA H . n 
A 1 88  LEU 88  88  88  LEU LEU H . n 
A 1 89  ARG 89  89  89  ARG ARG H . n 
A 1 90  ALA 90  90  90  ALA ALA H . n 
A 1 91  GLU 91  91  91  GLU GLU H . n 
A 1 92  ASP 92  92  92  ASP ASP H . n 
A 1 93  SER 93  93  93  SER SER H . n 
A 1 94  ALA 94  94  94  ALA ALA H . n 
A 1 95  THR 95  95  95  THR THR H . n 
A 1 96  TYR 96  96  96  TYR TYR H . n 
A 1 97  TYR 97  97  97  TYR TYR H . n 
A 1 98  CYS 98  98  98  CYS CYS H . n 
A 1 99  ALA 99  99  99  ALA ALA H . n 
A 1 100 ARG 100 100 100 ARG ARG H . n 
A 1 101 SER 101 101 101 SER SER H . n 
A 1 102 ARG 102 102 102 ARG ARG H . n 
A 1 103 TYR 103 103 103 TYR TYR H . n 
A 1 104 TYR 104 104 104 TYR TYR H . n 
A 1 105 GLY 105 105 105 GLY GLY H . n 
A 1 106 GLY 106 106 106 GLY GLY H . n 
A 1 107 THR 107 107 107 THR THR H . n 
A 1 108 TYR 108 108 108 TYR TYR H . n 
A 1 109 ARG 109 109 109 ARG ARG H . n 
A 1 110 TYR 110 110 110 TYR TYR H . n 
A 1 111 ALA 111 111 111 ALA ALA H . n 
A 1 112 LEU 112 112 112 LEU LEU H . n 
A 1 113 ASP 113 113 113 ASP ASP H . n 
A 1 114 TYR 114 114 114 TYR TYR H . n 
A 1 115 TRP 115 115 115 TRP TRP H . n 
A 1 116 GLY 116 116 116 GLY GLY H . n 
A 1 117 GLN 117 117 117 GLN GLN H . n 
A 1 118 GLY 118 118 118 GLY GLY H . n 
A 1 119 THR 119 119 119 THR THR H . n 
A 1 120 SER 120 120 120 SER SER H . n 
A 1 121 VAL 121 121 121 VAL VAL H . n 
A 1 122 THR 122 122 122 THR THR H . n 
A 1 123 VAL 123 123 123 VAL VAL H . n 
A 1 124 SER 124 124 124 SER SER H . n 
B 2 1   GLU 1   1   ?   ?   ?   L . n 
B 2 2   ASN 2   2   2   ASN ASN L . n 
B 2 3   VAL 3   3   3   VAL VAL L . n 
B 2 4   LEU 4   4   4   LEU LEU L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   PRO 9   9   9   PRO PRO L . n 
B 2 10  ILE 10  10  10  ILE ILE L . n 
B 2 11  MET 11  11  11  MET MET L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  PRO 15  15  15  PRO PRO L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  GLU 17  17  17  GLU GLU L . n 
B 2 18  LYS 18  18  18  LYS LYS L . n 
B 2 19  VAL 19  19  19  VAL VAL L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  MET 21  21  21  MET MET L . n 
B 2 22  THR 22  22  22  THR THR L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  SER 27  27  27  SER SER L . n 
B 2 28  SER 28  28  28  SER SER L . n 
B 2 29  VAL 29  29  29  VAL VAL L . n 
B 2 30  SER 30  30  30  SER SER L . n 
B 2 31  SER 31  31  31  SER SER L . n 
B 2 32  SER 32  32  32  SER SER L . n 
B 2 33  TYR 33  33  33  TYR TYR L . n 
B 2 34  LEU 34  34  34  LEU LEU L . n 
B 2 35  HIS 35  35  35  HIS HIS L . n 
B 2 36  TRP 36  36  36  TRP TRP L . n 
B 2 37  TYR 37  37  37  TYR TYR L . n 
B 2 38  GLN 38  38  38  GLN GLN L . n 
B 2 39  GLN 39  39  39  GLN GLN L . n 
B 2 40  LYS 40  40  40  LYS LYS L . n 
B 2 41  SER 41  41  41  SER SER L . n 
B 2 42  GLY 42  42  42  GLY GLY L . n 
B 2 43  ALA 43  43  43  ALA ALA L . n 
B 2 44  SER 44  44  44  SER SER L . n 
B 2 45  PRO 45  45  45  PRO PRO L . n 
B 2 46  LYS 46  46  46  LYS LYS L . n 
B 2 47  LEU 47  47  47  LEU LEU L . n 
B 2 48  TRP 48  48  48  TRP TRP L . n 
B 2 49  ILE 49  49  49  ILE ILE L . n 
B 2 50  TYR 50  50  50  TYR TYR L . n 
B 2 51  SER 51  51  51  SER SER L . n 
B 2 52  THR 52  52  52  THR THR L . n 
B 2 53  SER 53  53  53  SER SER L . n 
B 2 54  ASN 54  54  54  ASN ASN L . n 
B 2 55  LEU 55  55  55  LEU LEU L . n 
B 2 56  ALA 56  56  56  ALA ALA L . n 
B 2 57  SER 57  57  57  SER SER L . n 
B 2 58  GLY 58  58  58  GLY GLY L . n 
B 2 59  VAL 59  59  59  VAL VAL L . n 
B 2 60  PRO 60  60  60  PRO PRO L . n 
B 2 61  ALA 61  61  61  ALA ALA L . n 
B 2 62  ARG 62  62  62  ARG ARG L . n 
B 2 63  PHE 63  63  63  PHE PHE L . n 
B 2 64  SER 64  64  64  SER SER L . n 
B 2 65  GLY 65  65  65  GLY GLY L . n 
B 2 66  SER 66  66  66  SER SER L . n 
B 2 67  GLY 67  67  67  GLY GLY L . n 
B 2 68  SER 68  68  68  SER SER L . n 
B 2 69  GLY 69  69  69  GLY GLY L . n 
B 2 70  THR 70  70  70  THR THR L . n 
B 2 71  SER 71  71  71  SER SER L . n 
B 2 72  TYR 72  72  72  TYR TYR L . n 
B 2 73  SER 73  73  73  SER SER L . n 
B 2 74  LEU 74  74  74  LEU LEU L . n 
B 2 75  THR 75  75  75  THR THR L . n 
B 2 76  ILE 76  76  76  ILE ILE L . n 
B 2 77  SER 77  77  77  SER SER L . n 
B 2 78  SER 78  78  78  SER SER L . n 
B 2 79  VAL 79  79  79  VAL VAL L . n 
B 2 80  GLU 80  80  80  GLU GLU L . n 
B 2 81  ALA 81  81  81  ALA ALA L . n 
B 2 82  GLU 82  82  82  GLU GLU L . n 
B 2 83  ASP 83  83  83  ASP ASP L . n 
B 2 84  ALA 84  84  84  ALA ALA L . n 
B 2 85  ALA 85  85  85  ALA ALA L . n 
B 2 86  THR 86  86  86  THR THR L . n 
B 2 87  TYR 87  87  87  TYR TYR L . n 
B 2 88  TYR 88  88  88  TYR TYR L . n 
B 2 89  CYS 89  89  89  CYS CYS L . n 
B 2 90  GLN 90  90  90  GLN GLN L . n 
B 2 91  GLN 91  91  91  GLN GLN L . n 
B 2 92  PHE 92  92  92  PHE PHE L . n 
B 2 93  SER 93  93  93  SER SER L . n 
B 2 94  GLY 94  94  94  GLY GLY L . n 
B 2 95  TYR 95  95  95  TYR TYR L . n 
B 2 96  PRO 96  96  96  PRO PRO L . n 
B 2 97  LEU 97  97  97  LEU LEU L . n 
B 2 98  THR 98  98  98  THR THR L . n 
B 2 99  PHE 99  99  99  PHE PHE L . n 
B 2 100 GLY 100 100 100 GLY GLY L . n 
B 2 101 ALA 101 101 101 ALA ALA L . n 
B 2 102 GLY 102 102 102 GLY GLY L . n 
B 2 103 THR 103 103 103 THR THR L . n 
B 2 104 LYS 104 104 104 LYS LYS L . n 
B 2 105 LEU 105 105 105 LEU LEU L . n 
B 2 106 GLU 106 106 106 GLU GLU L . n 
B 2 107 LEU 107 107 107 LEU LEU L . n 
B 2 108 LYS 108 108 108 LYS LYS L . n 
C 3 1   GLY 1   1   ?   ?   ?   A . n 
C 3 2   PRO 2   2   ?   ?   ?   A . n 
C 3 3   VAL 3   3   ?   ?   ?   A . n 
C 3 4   GLU 4   4   ?   ?   ?   A . n 
C 3 5   GLU 5   5   ?   ?   ?   A . n 
C 3 6   SER 6   6   ?   ?   ?   A . n 
C 3 7   VAL 7   7   ?   ?   ?   A . n 
C 3 8   ASP 8   8   ?   ?   ?   A . n 
C 3 9   ARG 9   9   ?   ?   ?   A . n 
C 3 10  ALA 10  10  ?   ?   ?   A . n 
C 3 11  VAL 11  11  ?   ?   ?   A . n 
C 3 12  ALA 12  12  ?   ?   ?   A . n 
C 3 13  ARG 13  13  ?   ?   ?   A . n 
C 3 14  VAL 14  14  ?   ?   ?   A . n 
C 3 15  ALA 15  15  ?   ?   ?   A . n 
C 3 16  ASP 16  16  ?   ?   ?   A . n 
C 3 17  THR 17  17  ?   ?   ?   A . n 
C 3 18  ILE 18  18  ?   ?   ?   A . n 
C 3 19  SER 19  19  ?   ?   ?   A . n 
C 3 20  SER 20  20  ?   ?   ?   A . n 
C 3 21  ARG 21  21  ?   ?   ?   A . n 
C 3 22  PRO 22  22  ?   ?   ?   A . n 
C 3 23  THR 23  23  ?   ?   ?   A . n 
C 3 24  ASN 24  24  ?   ?   ?   A . n 
C 3 25  SER 25  25  ?   ?   ?   A . n 
C 3 26  GLU 26  26  ?   ?   ?   A . n 
C 3 27  SER 27  27  ?   ?   ?   A . n 
C 3 28  ILE 28  28  ?   ?   ?   A . n 
C 3 29  PRO 29  29  ?   ?   ?   A . n 
C 3 30  ALA 30  30  ?   ?   ?   A . n 
C 3 31  LEU 31  31  ?   ?   ?   A . n 
C 3 32  THR 32  32  ?   ?   ?   A . n 
C 3 33  ALA 33  33  ?   ?   ?   A . n 
C 3 34  ALA 34  34  ?   ?   ?   A . n 
C 3 35  GLU 35  35  ?   ?   ?   A . n 
C 3 36  THR 36  36  ?   ?   ?   A . n 
C 3 37  GLY 37  37  ?   ?   ?   A . n 
C 3 38  HIS 38  38  ?   ?   ?   A . n 
C 3 39  THR 39  39  ?   ?   ?   A . n 
C 3 40  SER 40  40  ?   ?   ?   A . n 
C 3 41  GLN 41  41  ?   ?   ?   A . n 
C 3 42  VAL 42  42  ?   ?   ?   A . n 
C 3 43  VAL 43  43  ?   ?   ?   A . n 
C 3 44  PRO 44  44  ?   ?   ?   A . n 
C 3 45  SER 45  45  ?   ?   ?   A . n 
C 3 46  ASP 46  46  ?   ?   ?   A . n 
C 3 47  THR 47  47  ?   ?   ?   A . n 
C 3 48  MET 48  48  ?   ?   ?   A . n 
C 3 49  GLN 49  49  ?   ?   ?   A . n 
C 3 50  THR 50  50  ?   ?   ?   A . n 
C 3 51  ARG 51  51  ?   ?   ?   A . n 
C 3 52  HIS 52  52  ?   ?   ?   A . n 
C 3 53  VAL 53  53  ?   ?   ?   A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ASN 55  55  ?   ?   ?   A . n 
C 3 56  TYR 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  SER 58  58  58  SER SER A . n 
C 3 59  ARG 59  59  59  ARG ARG A . n 
C 3 60  SER 60  60  60  SER SER A . n 
C 3 61  GLU 61  61  61  GLU GLU A . n 
C 3 62  SER 62  62  62  SER SER A . n 
C 3 63  SER 63  63  63  SER SER A . n 
C 3 64  ILE 64  64  64  ILE ILE A . n 
C 3 65  GLU 65  65  65  GLU GLU A . n 
C 3 66  ASN 66  66  66  ASN ASN A . n 
C 3 67  PHE 67  67  67  PHE PHE A . n 
C 3 68  LEU 68  68  68  LEU LEU A . n 
C 3 69  CYS 69  69  69  CYS CYS A . n 
C 3 70  ARG 70  70  70  ARG ARG A . n 
C 3 71  SER 71  71  71  SER SER A . n 
C 3 72  ALA 72  72  72  ALA ALA A . n 
C 3 73  CYS 73  73  73  CYS CYS A . n 
C 3 74  VAL 74  74  74  VAL VAL A . n 
C 3 75  TYR 75  75  75  TYR TYR A . n 
C 3 76  TYR 76  76  76  TYR TYR A . n 
C 3 77  ALA 77  77  77  ALA ALA A . n 
C 3 78  THR 78  78  78  THR THR A . n 
C 3 79  TYR 79  79  79  TYR TYR A . n 
C 3 80  THR 80  80  80  THR THR A . n 
C 3 81  ASN 81  81  81  ASN ASN A . n 
C 3 82  ASN 82  82  82  ASN ASN A . n 
C 3 83  SER 83  83  83  SER SER A . n 
C 3 84  LYS 84  84  84  LYS LYS A . n 
C 3 85  LYS 85  85  85  LYS LYS A . n 
C 3 86  GLY 86  86  86  GLY GLY A . n 
C 3 87  PHE 87  87  87  PHE PHE A . n 
C 3 88  ALA 88  88  88  ALA ALA A . n 
C 3 89  GLU 89  89  89  GLU GLU A . n 
C 3 90  TRP 90  90  90  TRP TRP A . n 
C 3 91  VAL 91  91  91  VAL VAL A . n 
C 3 92  ILE 92  92  92  ILE ILE A . n 
C 3 93  ASN 93  93  93  ASN ASN A . n 
C 3 94  THR 94  94  94  THR THR A . n 
C 3 95  ARG 95  95  95  ARG ARG A . n 
C 3 96  GLN 96  96  96  GLN GLN A . n 
C 3 97  VAL 97  97  97  VAL VAL A . n 
C 3 98  ALA 98  98  98  ALA ALA A . n 
C 3 99  GLN 99  99  99  GLN GLN A . n 
C 3 100 LEU 100 100 100 LEU LEU A . n 
C 3 101 ARG 101 101 101 ARG ARG A . n 
C 3 102 ARG 102 102 102 ARG ARG A . n 
C 3 103 LYS 103 103 103 LYS LYS A . n 
C 3 104 LEU 104 104 104 LEU LEU A . n 
C 3 105 GLU 105 105 105 GLU GLU A . n 
C 3 106 LEU 106 106 106 LEU LEU A . n 
C 3 107 PHE 107 107 107 PHE PHE A . n 
C 3 108 THR 108 108 108 THR THR A . n 
C 3 109 TYR 109 109 109 TYR TYR A . n 
C 3 110 LEU 110 110 110 LEU LEU A . n 
C 3 111 ARG 111 111 111 ARG ARG A . n 
C 3 112 PHE 112 112 112 PHE PHE A . n 
C 3 113 ASP 113 113 113 ASP ASP A . n 
C 3 114 LEU 114 114 114 LEU LEU A . n 
C 3 115 GLU 115 115 115 GLU GLU A . n 
C 3 116 LEU 116 116 116 LEU LEU A . n 
C 3 117 THR 117 117 117 THR THR A . n 
C 3 118 PHE 118 118 118 PHE PHE A . n 
C 3 119 VAL 119 119 119 VAL VAL A . n 
C 3 120 ILE 120 120 120 ILE ILE A . n 
C 3 121 THR 121 121 121 THR THR A . n 
C 3 122 SER 122 122 122 SER SER A . n 
C 3 123 ALA 123 123 123 ALA ALA A . n 
C 3 124 GLN 124 124 124 GLN GLN A . n 
C 3 125 GLN 125 125 125 GLN GLN A . n 
C 3 126 PRO 126 126 126 PRO PRO A . n 
C 3 127 SER 127 127 127 SER SER A . n 
C 3 128 THR 128 128 128 THR THR A . n 
C 3 129 ALA 129 129 129 ALA ALA A . n 
C 3 130 SER 130 130 130 SER SER A . n 
C 3 131 SER 131 131 131 SER SER A . n 
C 3 132 VAL 132 132 132 VAL VAL A . n 
C 3 133 ASP 133 133 133 ASP ASP A . n 
C 3 134 ALA 134 134 134 ALA ALA A . n 
C 3 135 PRO 135 135 135 PRO PRO A . n 
C 3 136 VAL 136 136 136 VAL VAL A . n 
C 3 137 GLN 137 137 137 GLN GLN A . n 
C 3 138 THR 138 138 138 THR THR A . n 
C 3 139 HIS 139 139 139 HIS HIS A . n 
C 3 140 GLN 140 140 140 GLN GLN A . n 
C 3 141 ILE 141 141 141 ILE ILE A . n 
C 3 142 MET 142 142 142 MET MET A . n 
C 3 143 TYR 143 143 143 TYR TYR A . n 
C 3 144 VAL 144 144 144 VAL VAL A . n 
C 3 145 PRO 145 145 145 PRO PRO A . n 
C 3 146 PRO 146 146 146 PRO PRO A . n 
C 3 147 GLY 147 147 147 GLY GLY A . n 
C 3 148 GLY 148 148 148 GLY GLY A . n 
C 3 149 PRO 149 149 149 PRO PRO A . n 
C 3 150 VAL 150 150 150 VAL VAL A . n 
C 3 151 PRO 151 151 151 PRO PRO A . n 
C 3 152 THR 152 152 152 THR THR A . n 
C 3 153 LYS 153 153 153 LYS LYS A . n 
C 3 154 VAL 154 154 154 VAL VAL A . n 
C 3 155 LYS 155 155 155 LYS LYS A . n 
C 3 156 ASP 156 156 156 ASP ASP A . n 
C 3 157 TYR 157 157 157 TYR TYR A . n 
C 3 158 ALA 158 158 158 ALA ALA A . n 
C 3 159 TRP 159 159 159 TRP TRP A . n 
C 3 160 GLN 160 160 160 GLN GLN A . n 
C 3 161 THR 161 161 161 THR THR A . n 
C 3 162 SER 162 162 162 SER SER A . n 
C 3 163 THR 163 163 163 THR THR A . n 
C 3 164 ASN 164 164 164 ASN ASN A . n 
C 3 165 PRO 165 165 165 PRO PRO A . n 
C 3 166 SER 166 166 166 SER SER A . n 
C 3 167 VAL 167 167 167 VAL VAL A . n 
C 3 168 PHE 168 168 168 PHE PHE A . n 
C 3 169 TRP 169 169 169 TRP TRP A . n 
C 3 170 THR 170 170 170 THR THR A . n 
C 3 171 GLU 171 171 171 GLU GLU A . n 
C 3 172 GLY 172 172 172 GLY GLY A . n 
C 3 173 ASN 173 173 173 ASN ASN A . n 
C 3 174 ALA 174 174 174 ALA ALA A . n 
C 3 175 PRO 175 175 175 PRO PRO A . n 
C 3 176 PRO 176 176 176 PRO PRO A . n 
C 3 177 ARG 177 177 177 ARG ARG A . n 
C 3 178 MET 178 178 178 MET MET A . n 
C 3 179 SER 179 179 179 SER SER A . n 
C 3 180 ILE 180 180 180 ILE ILE A . n 
C 3 181 PRO 181 181 181 PRO PRO A . n 
C 3 182 PHE 182 182 182 PHE PHE A . n 
C 3 183 ILE 183 183 183 ILE ILE A . n 
C 3 184 SER 184 184 184 SER SER A . n 
C 3 185 ILE 185 185 185 ILE ILE A . n 
C 3 186 GLY 186 186 186 GLY GLY A . n 
C 3 187 ASN 187 187 187 ASN ASN A . n 
C 3 188 ALA 188 188 188 ALA ALA A . n 
C 3 189 TYR 189 189 189 TYR TYR A . n 
C 3 190 SER 190 190 190 SER SER A . n 
C 3 191 CYS 191 191 191 CYS CYS A . n 
C 3 192 PHE 192 192 192 PHE PHE A . n 
C 3 193 TYR 193 193 193 TYR TYR A . n 
C 3 194 ASP 194 194 194 ASP ASP A . n 
C 3 195 GLY 195 195 195 GLY GLY A . n 
C 3 196 TRP 196 196 196 TRP TRP A . n 
C 3 197 THR 197 197 197 THR THR A . n 
C 3 198 GLN 198 198 ?   ?   ?   A . n 
C 3 199 PHE 199 199 ?   ?   ?   A . n 
C 3 200 SER 200 200 ?   ?   ?   A . n 
C 3 201 ARG 201 201 ?   ?   ?   A . n 
C 3 202 ASN 202 202 ?   ?   ?   A . n 
C 3 203 GLY 203 203 ?   ?   ?   A . n 
C 3 204 VAL 204 204 204 VAL VAL A . n 
C 3 205 TYR 205 205 205 TYR TYR A . n 
C 3 206 GLY 206 206 206 GLY GLY A . n 
C 3 207 ILE 207 207 207 ILE ILE A . n 
C 3 208 ASN 208 208 208 ASN ASN A . n 
C 3 209 THR 209 209 209 THR THR A . n 
C 3 210 LEU 210 210 210 LEU LEU A . n 
C 3 211 ASN 211 211 211 ASN ASN A . n 
C 3 212 ASN 212 212 212 ASN ASN A . n 
C 3 213 MET 213 213 213 MET MET A . n 
C 3 214 GLY 214 214 214 GLY GLY A . n 
C 3 215 THR 215 215 215 THR THR A . n 
C 3 216 LEU 216 216 216 LEU LEU A . n 
C 3 217 TYR 217 217 217 TYR TYR A . n 
C 3 218 MET 218 218 218 MET MET A . n 
C 3 219 ARG 219 219 219 ARG ARG A . n 
C 3 220 HIS 220 220 220 HIS HIS A . n 
C 3 221 VAL 221 221 221 VAL VAL A . n 
C 3 222 ASN 222 222 222 ASN ASN A . n 
C 3 223 GLU 223 223 223 GLU GLU A . n 
C 3 224 ALA 224 224 224 ALA ALA A . n 
C 3 225 GLY 225 225 225 GLY GLY A . n 
C 3 226 GLN 226 226 226 GLN GLN A . n 
C 3 227 GLY 227 227 227 GLY GLY A . n 
C 3 228 PRO 228 228 228 PRO PRO A . n 
C 3 229 ILE 229 229 229 ILE ILE A . n 
C 3 230 LYS 230 230 230 LYS LYS A . n 
C 3 231 SER 231 231 231 SER SER A . n 
C 3 232 THR 232 232 232 THR THR A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 ARG 234 234 234 ARG ARG A . n 
C 3 235 ILE 235 235 235 ILE ILE A . n 
C 3 236 TYR 236 236 236 TYR TYR A . n 
C 3 237 PHE 237 237 237 PHE PHE A . n 
C 3 238 LYS 238 238 238 LYS LYS A . n 
C 3 239 PRO 239 239 239 PRO PRO A . n 
C 3 240 LYS 240 240 240 LYS LYS A . n 
C 3 241 HIS 241 241 241 HIS HIS A . n 
C 3 242 VAL 242 242 242 VAL VAL A . n 
C 3 243 LYS 243 243 243 LYS LYS A . n 
C 3 244 ALA 244 244 244 ALA ALA A . n 
C 3 245 TRP 245 245 245 TRP TRP A . n 
C 3 246 VAL 246 246 246 VAL VAL A . n 
C 3 247 PRO 247 247 247 PRO PRO A . n 
C 3 248 ARG 248 248 248 ARG ARG A . n 
C 3 249 PRO 249 249 249 PRO PRO A . n 
C 3 250 PRO 250 250 250 PRO PRO A . n 
C 3 251 ARG 251 251 251 ARG ARG A . n 
C 3 252 LEU 252 252 252 LEU LEU A . n 
C 3 253 CYS 253 253 253 CYS CYS A . n 
C 3 254 GLN 254 254 254 GLN GLN A . n 
C 3 255 TYR 255 255 255 TYR TYR A . n 
C 3 256 GLU 256 256 256 GLU GLU A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 GLN 258 258 258 GLN GLN A . n 
C 3 259 LYS 259 259 259 LYS LYS A . n 
C 3 260 ASN 260 260 260 ASN ASN A . n 
C 3 261 VAL 261 261 261 VAL VAL A . n 
C 3 262 ASN 262 262 262 ASN ASN A . n 
C 3 263 PHE 263 263 263 PHE PHE A . n 
C 3 264 SER 264 264 264 SER SER A . n 
C 3 265 PRO 265 265 265 PRO PRO A . n 
C 3 266 ILE 266 266 266 ILE ILE A . n 
C 3 267 GLY 267 267 267 GLY GLY A . n 
C 3 268 VAL 268 268 268 VAL VAL A . n 
C 3 269 THR 269 269 269 THR THR A . n 
C 3 270 THR 270 270 270 THR THR A . n 
C 3 271 SER 271 271 271 SER SER A . n 
C 3 272 ARG 272 272 272 ARG ARG A . n 
C 3 273 THR 273 273 273 THR THR A . n 
C 3 274 ASP 274 274 274 ASP ASP A . n 
C 3 275 ILE 275 275 275 ILE ILE A . n 
C 3 276 ILE 276 276 276 ILE ILE A . n 
C 3 277 THR 277 277 ?   ?   ?   A . n 
C 3 278 THR 278 278 ?   ?   ?   A . n 
D 4 1   SER 1   1   ?   ?   ?   B . n 
D 4 2   PRO 2   2   ?   ?   ?   B . n 
D 4 3   SER 3   3   ?   ?   ?   B . n 
D 4 4   ALA 4   4   ?   ?   ?   B . n 
D 4 5   GLU 5   5   ?   ?   ?   B . n 
D 4 6   GLU 6   6   ?   ?   ?   B . n 
D 4 7   CYS 7   7   ?   ?   ?   B . n 
D 4 8   GLY 8   8   ?   ?   ?   B . n 
D 4 9   TYR 9   9   ?   ?   ?   B . n 
D 4 10  SER 10  10  ?   ?   ?   B . n 
D 4 11  ASP 11  11  ?   ?   ?   B . n 
D 4 12  ARG 12  12  ?   ?   ?   B . n 
D 4 13  VAL 13  13  ?   ?   ?   B . n 
D 4 14  ARG 14  14  14  ARG ARG B . n 
D 4 15  SER 15  15  15  SER SER B . n 
D 4 16  ILE 16  16  16  ILE ILE B . n 
D 4 17  THR 17  17  17  THR THR B . n 
D 4 18  LEU 18  18  18  LEU LEU B . n 
D 4 19  GLY 19  19  19  GLY GLY B . n 
D 4 20  ASN 20  20  20  ASN ASN B . n 
D 4 21  SER 21  21  21  SER SER B . n 
D 4 22  THR 22  22  22  THR THR B . n 
D 4 23  ILE 23  23  23  ILE ILE B . n 
D 4 24  THR 24  24  24  THR THR B . n 
D 4 25  THR 25  25  25  THR THR B . n 
D 4 26  GLN 26  26  26  GLN GLN B . n 
D 4 27  GLU 27  27  ?   ?   ?   B . n 
D 4 28  CYS 28  28  ?   ?   ?   B . n 
D 4 29  ALA 29  29  ?   ?   ?   B . n 
D 4 30  ASN 30  30  30  ASN ASN B . n 
D 4 31  VAL 31  31  31  VAL VAL B . n 
D 4 32  VAL 32  32  32  VAL VAL B . n 
D 4 33  VAL 33  33  33  VAL VAL B . n 
D 4 34  GLY 34  34  34  GLY GLY B . n 
D 4 35  TYR 35  35  35  TYR TYR B . n 
D 4 36  GLY 36  36  36  GLY GLY B . n 
D 4 37  VAL 37  37  37  VAL VAL B . n 
D 4 38  TRP 38  38  38  TRP TRP B . n 
D 4 39  PRO 39  39  39  PRO PRO B . n 
D 4 40  GLU 40  40  40  GLU GLU B . n 
D 4 41  TYR 41  41  41  TYR TYR B . n 
D 4 42  LEU 42  42  42  LEU LEU B . n 
D 4 43  LYS 43  43  ?   ?   ?   B . n 
D 4 44  ASP 44  44  ?   ?   ?   B . n 
D 4 45  ASN 45  45  ?   ?   ?   B . n 
D 4 46  GLU 46  46  ?   ?   ?   B . n 
D 4 47  ALA 47  47  ?   ?   ?   B . n 
D 4 48  THR 48  48  ?   ?   ?   B . n 
D 4 49  ALA 49  49  ?   ?   ?   B . n 
D 4 50  GLU 50  50  ?   ?   ?   B . n 
D 4 51  ASP 51  51  51  ASP ASP B . n 
D 4 52  GLN 52  52  52  GLN GLN B . n 
D 4 53  PRO 53  53  53  PRO PRO B . n 
D 4 54  THR 54  54  54  THR THR B . n 
D 4 55  GLN 55  55  55  GLN GLN B . n 
D 4 56  PRO 56  56  56  PRO PRO B . n 
D 4 57  ASP 57  57  57  ASP ASP B . n 
D 4 58  VAL 58  58  58  VAL VAL B . n 
D 4 59  ALA 59  59  59  ALA ALA B . n 
D 4 60  THR 60  60  60  THR THR B . n 
D 4 61  CYS 61  61  61  CYS CYS B . n 
D 4 62  ARG 62  62  62  ARG ARG B . n 
D 4 63  PHE 63  63  63  PHE PHE B . n 
D 4 64  TYR 64  64  64  TYR TYR B . n 
D 4 65  THR 65  65  65  THR THR B . n 
D 4 66  LEU 66  66  66  LEU LEU B . n 
D 4 67  GLU 67  67  67  GLU GLU B . n 
D 4 68  SER 68  68  68  SER SER B . n 
D 4 69  VAL 69  69  69  VAL VAL B . n 
D 4 70  GLN 70  70  70  GLN GLN B . n 
D 4 71  TRP 71  71  71  TRP TRP B . n 
D 4 72  MET 72  72  72  MET MET B . n 
D 4 73  LYS 73  73  73  LYS LYS B . n 
D 4 74  ASN 74  74  74  ASN ASN B . n 
D 4 75  SER 75  75  75  SER SER B . n 
D 4 76  ALA 76  76  76  ALA ALA B . n 
D 4 77  GLY 77  77  77  GLY GLY B . n 
D 4 78  TRP 78  78  78  TRP TRP B . n 
D 4 79  TRP 79  79  79  TRP TRP B . n 
D 4 80  TRP 80  80  80  TRP TRP B . n 
D 4 81  LYS 81  81  81  LYS LYS B . n 
D 4 82  LEU 82  82  82  LEU LEU B . n 
D 4 83  PRO 83  83  83  PRO PRO B . n 
D 4 84  ASP 84  84  84  ASP ASP B . n 
D 4 85  ALA 85  85  85  ALA ALA B . n 
D 4 86  LEU 86  86  86  LEU LEU B . n 
D 4 87  SER 87  87  87  SER SER B . n 
D 4 88  GLN 88  88  88  GLN GLN B . n 
D 4 89  MET 89  89  89  MET MET B . n 
D 4 90  GLY 90  90  90  GLY GLY B . n 
D 4 91  LEU 91  91  91  LEU LEU B . n 
D 4 92  PHE 92  92  92  PHE PHE B . n 
D 4 93  GLY 93  93  93  GLY GLY B . n 
D 4 94  GLN 94  94  94  GLN GLN B . n 
D 4 95  ASN 95  95  95  ASN ASN B . n 
D 4 96  MET 96  96  96  MET MET B . n 
D 4 97  GLN 97  97  97  GLN GLN B . n 
D 4 98  TYR 98  98  98  TYR TYR B . n 
D 4 99  HIS 99  99  99  HIS HIS B . n 
D 4 100 TYR 100 100 100 TYR TYR B . n 
D 4 101 LEU 101 101 101 LEU LEU B . n 
D 4 102 GLY 102 102 102 GLY GLY B . n 
D 4 103 ARG 103 103 103 ARG ARG B . n 
D 4 104 THR 104 104 104 THR THR B . n 
D 4 105 GLY 105 105 105 GLY GLY B . n 
D 4 106 TYR 106 106 106 TYR TYR B . n 
D 4 107 THR 107 107 107 THR THR B . n 
D 4 108 ILE 108 108 108 ILE ILE B . n 
D 4 109 HIS 109 109 109 HIS HIS B . n 
D 4 110 VAL 110 110 110 VAL VAL B . n 
D 4 111 GLN 111 111 111 GLN GLN B . n 
D 4 112 CYS 112 112 112 CYS CYS B . n 
D 4 113 ASN 113 113 113 ASN ASN B . n 
D 4 114 ALA 114 114 114 ALA ALA B . n 
D 4 115 SER 115 115 115 SER SER B . n 
D 4 116 LYS 116 116 116 LYS LYS B . n 
D 4 117 PHE 117 117 117 PHE PHE B . n 
D 4 118 HIS 118 118 118 HIS HIS B . n 
D 4 119 GLN 119 119 119 GLN GLN B . n 
D 4 120 GLY 120 120 120 GLY GLY B . n 
D 4 121 CYS 121 121 121 CYS CYS B . n 
D 4 122 LEU 122 122 122 LEU LEU B . n 
D 4 123 LEU 123 123 123 LEU LEU B . n 
D 4 124 VAL 124 124 124 VAL VAL B . n 
D 4 125 VAL 125 125 125 VAL VAL B . n 
D 4 126 CYS 126 126 126 CYS CYS B . n 
D 4 127 VAL 127 127 127 VAL VAL B . n 
D 4 128 PRO 128 128 128 PRO PRO B . n 
D 4 129 GLU 129 129 129 GLU GLU B . n 
D 4 130 ALA 130 130 130 ALA ALA B . n 
D 4 131 GLU 131 131 131 GLU GLU B . n 
D 4 132 MET 132 132 132 MET MET B . n 
D 4 133 GLY 133 133 133 GLY GLY B . n 
D 4 134 CYS 134 134 134 CYS CYS B . n 
D 4 135 SER 135 135 135 SER SER B . n 
D 4 136 ASN 136 136 136 ASN ASN B . n 
D 4 137 LEU 137 137 137 LEU LEU B . n 
D 4 138 ASN 138 138 138 ASN ASN B . n 
D 4 139 ASN 139 139 139 ASN ASN B . n 
D 4 140 THR 140 140 140 THR THR B . n 
D 4 141 PRO 141 141 141 PRO PRO B . n 
D 4 142 GLU 142 142 142 GLU GLU B . n 
D 4 143 PHE 143 143 143 PHE PHE B . n 
D 4 144 SER 144 144 144 SER SER B . n 
D 4 145 GLU 145 145 145 GLU GLU B . n 
D 4 146 LEU 146 146 146 LEU LEU B . n 
D 4 147 SER 147 147 147 SER SER B . n 
D 4 148 GLY 148 148 148 GLY GLY B . n 
D 4 149 GLY 149 149 149 GLY GLY B . n 
D 4 150 ASP 150 150 150 ASP ASP B . n 
D 4 151 SER 151 151 151 SER SER B . n 
D 4 152 ALA 152 152 152 ALA ALA B . n 
D 4 153 ARG 153 153 153 ARG ARG B . n 
D 4 154 MET 154 154 154 MET MET B . n 
D 4 155 PHE 155 155 155 PHE PHE B . n 
D 4 156 THR 156 156 156 THR THR B . n 
D 4 157 ASP 157 157 157 ASP ASP B . n 
D 4 158 THR 158 158 158 THR THR B . n 
D 4 159 GLN 159 159 159 GLN GLN B . n 
D 4 160 VAL 160 160 160 VAL VAL B . n 
D 4 161 GLY 161 161 161 GLY GLY B . n 
D 4 162 GLU 162 162 162 GLU GLU B . n 
D 4 163 SER 163 163 163 SER SER B . n 
D 4 164 ASN 164 164 164 ASN ASN B . n 
D 4 165 ALA 165 165 165 ALA ALA B . n 
D 4 166 LYS 166 166 166 LYS LYS B . n 
D 4 167 LYS 167 167 167 LYS LYS B . n 
D 4 168 VAL 168 168 168 VAL VAL B . n 
D 4 169 GLN 169 169 169 GLN GLN B . n 
D 4 170 THR 170 170 170 THR THR B . n 
D 4 171 ALA 171 171 171 ALA ALA B . n 
D 4 172 VAL 172 172 172 VAL VAL B . n 
D 4 173 TRP 173 173 173 TRP TRP B . n 
D 4 174 ASN 174 174 174 ASN ASN B . n 
D 4 175 ALA 175 175 175 ALA ALA B . n 
D 4 176 GLY 176 176 176 GLY GLY B . n 
D 4 177 MET 177 177 177 MET MET B . n 
D 4 178 GLY 178 178 178 GLY GLY B . n 
D 4 179 VAL 179 179 179 VAL VAL B . n 
D 4 180 GLY 180 180 180 GLY GLY B . n 
D 4 181 VAL 181 181 181 VAL VAL B . n 
D 4 182 GLY 182 182 182 GLY GLY B . n 
D 4 183 ASN 183 183 183 ASN ASN B . n 
D 4 184 LEU 184 184 184 LEU LEU B . n 
D 4 185 THR 185 185 185 THR THR B . n 
D 4 186 ILE 186 186 186 ILE ILE B . n 
D 4 187 PHE 187 187 187 PHE PHE B . n 
D 4 188 PRO 188 188 188 PRO PRO B . n 
D 4 189 HIS 189 189 189 HIS HIS B . n 
D 4 190 GLN 190 190 190 GLN GLN B . n 
D 4 191 TRP 191 191 191 TRP TRP B . n 
D 4 192 ILE 192 192 192 ILE ILE B . n 
D 4 193 ASN 193 193 193 ASN ASN B . n 
D 4 194 LEU 194 194 194 LEU LEU B . n 
D 4 195 ARG 195 195 195 ARG ARG B . n 
D 4 196 THR 196 196 196 THR THR B . n 
D 4 197 ASN 197 197 197 ASN ASN B . n 
D 4 198 ASN 198 198 198 ASN ASN B . n 
D 4 199 SER 199 199 199 SER SER B . n 
D 4 200 ALA 200 200 200 ALA ALA B . n 
D 4 201 THR 201 201 201 THR THR B . n 
D 4 202 LEU 202 202 202 LEU LEU B . n 
D 4 203 VAL 203 203 203 VAL VAL B . n 
D 4 204 MET 204 204 204 MET MET B . n 
D 4 205 PRO 205 205 205 PRO PRO B . n 
D 4 206 TYR 206 206 206 TYR TYR B . n 
D 4 207 ILE 207 207 207 ILE ILE B . n 
D 4 208 ASN 208 208 208 ASN ASN B . n 
D 4 209 SER 209 209 209 SER SER B . n 
D 4 210 VAL 210 210 210 VAL VAL B . n 
D 4 211 PRO 211 211 211 PRO PRO B . n 
D 4 212 MET 212 212 212 MET MET B . n 
D 4 213 ASP 213 213 213 ASP ASP B . n 
D 4 214 ASN 214 214 214 ASN ASN B . n 
D 4 215 MET 215 215 215 MET MET B . n 
D 4 216 PHE 216 216 216 PHE PHE B . n 
D 4 217 ARG 217 217 217 ARG ARG B . n 
D 4 218 HIS 218 218 218 HIS HIS B . n 
D 4 219 ASN 219 219 219 ASN ASN B . n 
D 4 220 ASN 220 220 220 ASN ASN B . n 
D 4 221 LEU 221 221 221 LEU LEU B . n 
D 4 222 THR 222 222 222 THR THR B . n 
D 4 223 LEU 223 223 223 LEU LEU B . n 
D 4 224 MET 224 224 224 MET MET B . n 
D 4 225 ILE 225 225 225 ILE ILE B . n 
D 4 226 ILE 226 226 226 ILE ILE B . n 
D 4 227 PRO 227 227 227 PRO PRO B . n 
D 4 228 PHE 228 228 228 PHE PHE B . n 
D 4 229 VAL 229 229 229 VAL VAL B . n 
D 4 230 PRO 230 230 230 PRO PRO B . n 
D 4 231 LEU 231 231 231 LEU LEU B . n 
D 4 232 ASN 232 232 232 ASN ASN B . n 
D 4 233 TYR 233 233 233 TYR TYR B . n 
D 4 234 SER 234 234 234 SER SER B . n 
D 4 235 GLU 235 235 235 GLU GLU B . n 
D 4 236 GLY 236 236 236 GLY GLY B . n 
D 4 237 SER 237 237 237 SER SER B . n 
D 4 238 SER 238 238 238 SER SER B . n 
D 4 239 PRO 239 239 239 PRO PRO B . n 
D 4 240 TYR 240 240 240 TYR TYR B . n 
D 4 241 VAL 241 241 241 VAL VAL B . n 
D 4 242 PRO 242 242 242 PRO PRO B . n 
D 4 243 ILE 243 243 243 ILE ILE B . n 
D 4 244 THR 244 244 244 THR THR B . n 
D 4 245 VAL 245 245 245 VAL VAL B . n 
D 4 246 THR 246 246 246 THR THR B . n 
D 4 247 ILE 247 247 247 ILE ILE B . n 
D 4 248 ALA 248 248 248 ALA ALA B . n 
D 4 249 PRO 249 249 249 PRO PRO B . n 
D 4 250 MET 250 250 250 MET MET B . n 
D 4 251 CYS 251 251 251 CYS CYS B . n 
D 4 252 ALA 252 252 252 ALA ALA B . n 
D 4 253 GLU 253 253 253 GLU GLU B . n 
D 4 254 TYR 254 254 254 TYR TYR B . n 
D 4 255 ASN 255 255 255 ASN ASN B . n 
D 4 256 GLY 256 256 256 GLY GLY B . n 
D 4 257 LEU 257 257 257 LEU LEU B . n 
D 4 258 ARG 258 258 ?   ?   ?   B . n 
D 4 259 LEU 259 259 ?   ?   ?   B . n 
D 4 260 ALA 260 260 ?   ?   ?   B . n 
D 4 261 SER 261 261 ?   ?   ?   B . n 
D 4 262 ASN 262 262 ?   ?   ?   B . n 
D 4 263 GLN 263 263 ?   ?   ?   B . n 
E 5 1   GLY 1   1   1   GLY GLY C . n 
E 5 2   LEU 2   2   2   LEU LEU C . n 
E 5 3   PRO 3   3   3   PRO PRO C . n 
E 5 4   VAL 4   4   4   VAL VAL C . n 
E 5 5   MET 5   5   5   MET MET C . n 
E 5 6   THR 6   6   6   THR THR C . n 
E 5 7   THR 7   7   7   THR THR C . n 
E 5 8   PRO 8   8   8   PRO PRO C . n 
E 5 9   GLY 9   9   9   GLY GLY C . n 
E 5 10  SER 10  10  10  SER SER C . n 
E 5 11  THR 11  11  11  THR THR C . n 
E 5 12  GLN 12  12  12  GLN GLN C . n 
E 5 13  PHE 13  13  13  PHE PHE C . n 
E 5 14  LEU 14  14  14  LEU LEU C . n 
E 5 15  THR 15  15  15  THR THR C . n 
E 5 16  SER 16  16  16  SER SER C . n 
E 5 17  ASP 17  17  17  ASP ASP C . n 
E 5 18  ASP 18  18  18  ASP ASP C . n 
E 5 19  PHE 19  19  19  PHE PHE C . n 
E 5 20  GLN 20  20  20  GLN GLN C . n 
E 5 21  SER 21  21  21  SER SER C . n 
E 5 22  PRO 22  22  22  PRO PRO C . n 
E 5 23  SER 23  23  23  SER SER C . n 
E 5 24  ALA 24  24  24  ALA ALA C . n 
E 5 25  MET 25  25  25  MET MET C . n 
E 5 26  PRO 26  26  26  PRO PRO C . n 
E 5 27  GLN 27  27  27  GLN GLN C . n 
E 5 28  PHE 28  28  28  PHE PHE C . n 
E 5 29  ASP 29  29  29  ASP ASP C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  THR 31  31  31  THR THR C . n 
E 5 32  PRO 32  32  32  PRO PRO C . n 
E 5 33  GLU 33  33  33  GLU GLU C . n 
E 5 34  MET 34  34  34  MET MET C . n 
E 5 35  GLN 35  35  35  GLN GLN C . n 
E 5 36  ILE 36  36  36  ILE ILE C . n 
E 5 37  PRO 37  37  37  PRO PRO C . n 
E 5 38  GLY 38  38  38  GLY GLY C . n 
E 5 39  ARG 39  39  39  ARG ARG C . n 
E 5 40  VAL 40  40  40  VAL VAL C . n 
E 5 41  ASN 41  41  41  ASN ASN C . n 
E 5 42  ASN 42  42  42  ASN ASN C . n 
E 5 43  LEU 43  43  43  LEU LEU C . n 
E 5 44  MET 44  44  44  MET MET C . n 
E 5 45  GLU 45  45  45  GLU GLU C . n 
E 5 46  ILE 46  46  46  ILE ILE C . n 
E 5 47  ALA 47  47  47  ALA ALA C . n 
E 5 48  GLU 48  48  48  GLU GLU C . n 
E 5 49  VAL 49  49  49  VAL VAL C . n 
E 5 50  ASP 50  50  50  ASP ASP C . n 
E 5 51  SER 51  51  51  SER SER C . n 
E 5 52  VAL 52  52  52  VAL VAL C . n 
E 5 53  VAL 53  53  53  VAL VAL C . n 
E 5 54  PRO 54  54  54  PRO PRO C . n 
E 5 55  VAL 55  55  55  VAL VAL C . n 
E 5 56  ASN 56  56  56  ASN ASN C . n 
E 5 57  ASN 57  57  57  ASN ASN C . n 
E 5 58  THR 58  58  58  THR THR C . n 
E 5 59  GLU 59  59  59  GLU GLU C . n 
E 5 60  ASP 60  60  60  ASP ASP C . n 
E 5 61  ASN 61  61  61  ASN ASN C . n 
E 5 62  VAL 62  62  62  VAL VAL C . n 
E 5 63  SER 63  63  63  SER SER C . n 
E 5 64  SER 64  64  64  SER SER C . n 
E 5 65  LEU 65  65  65  LEU LEU C . n 
E 5 66  LYS 66  66  66  LYS LYS C . n 
E 5 67  ALA 67  67  67  ALA ALA C . n 
E 5 68  TYR 68  68  68  TYR TYR C . n 
E 5 69  GLN 69  69  69  GLN GLN C . n 
E 5 70  ILE 70  70  70  ILE ILE C . n 
E 5 71  PRO 71  71  71  PRO PRO C . n 
E 5 72  VAL 72  72  72  VAL VAL C . n 
E 5 73  GLN 73  73  73  GLN GLN C . n 
E 5 74  SER 74  74  74  SER SER C . n 
E 5 75  ASN 75  75  75  ASN ASN C . n 
E 5 76  SER 76  76  76  SER SER C . n 
E 5 77  ASP 77  77  77  ASP ASP C . n 
E 5 78  ASN 78  78  78  ASN ASN C . n 
E 5 79  GLY 79  79  79  GLY GLY C . n 
E 5 80  LYS 80  80  80  LYS LYS C . n 
E 5 81  GLN 81  81  81  GLN GLN C . n 
E 5 82  VAL 82  82  82  VAL VAL C . n 
E 5 83  PHE 83  83  83  PHE PHE C . n 
E 5 84  GLY 84  84  84  GLY GLY C . n 
E 5 85  PHE 85  85  85  PHE PHE C . n 
E 5 86  PRO 86  86  86  PRO PRO C . n 
E 5 87  LEU 87  87  87  LEU LEU C . n 
E 5 88  GLN 88  88  88  GLN GLN C . n 
E 5 89  PRO 89  89  89  PRO PRO C . n 
E 5 90  GLY 90  90  90  GLY GLY C . n 
E 5 91  ALA 91  91  91  ALA ALA C . n 
E 5 92  ASN 92  92  92  ASN ASN C . n 
E 5 93  ASN 93  93  93  ASN ASN C . n 
E 5 94  VAL 94  94  94  VAL VAL C . n 
E 5 95  LEU 95  95  95  LEU LEU C . n 
E 5 96  ASN 96  96  96  ASN ASN C . n 
E 5 97  ARG 97  97  97  ARG ARG C . n 
E 5 98  THR 98  98  98  THR THR C . n 
E 5 99  LEU 99  99  99  LEU LEU C . n 
E 5 100 LEU 100 100 100 LEU LEU C . n 
E 5 101 GLY 101 101 101 GLY GLY C . n 
E 5 102 GLU 102 102 102 GLU GLU C . n 
E 5 103 ILE 103 103 103 ILE ILE C . n 
E 5 104 LEU 104 104 104 LEU LEU C . n 
E 5 105 ASN 105 105 105 ASN ASN C . n 
E 5 106 TYR 106 106 106 TYR TYR C . n 
E 5 107 TYR 107 107 107 TYR TYR C . n 
E 5 108 THR 108 108 108 THR THR C . n 
E 5 109 HIS 109 109 109 HIS HIS C . n 
E 5 110 TRP 110 110 110 TRP TRP C . n 
E 5 111 SER 111 111 111 SER SER C . n 
E 5 112 GLY 112 112 112 GLY GLY C . n 
E 5 113 SER 113 113 113 SER SER C . n 
E 5 114 ILE 114 114 114 ILE ILE C . n 
E 5 115 LYS 115 115 115 LYS LYS C . n 
E 5 116 LEU 116 116 116 LEU LEU C . n 
E 5 117 THR 117 117 117 THR THR C . n 
E 5 118 PHE 118 118 118 PHE PHE C . n 
E 5 119 MET 119 119 119 MET MET C . n 
E 5 120 PHE 120 120 120 PHE PHE C . n 
E 5 121 CYS 121 121 121 CYS CYS C . n 
E 5 122 GLY 122 122 122 GLY GLY C . n 
E 5 123 SER 123 123 123 SER SER C . n 
E 5 124 ALA 124 124 124 ALA ALA C . n 
E 5 125 MET 125 125 125 MET MET C . n 
E 5 126 ALA 126 126 126 ALA ALA C . n 
E 5 127 THR 127 127 127 THR THR C . n 
E 5 128 GLY 128 128 128 GLY GLY C . n 
E 5 129 LYS 129 129 129 LYS LYS C . n 
E 5 130 PHE 130 130 130 PHE PHE C . n 
E 5 131 LEU 131 131 131 LEU LEU C . n 
E 5 132 LEU 132 132 132 LEU LEU C . n 
E 5 133 ALA 133 133 133 ALA ALA C . n 
E 5 134 TYR 134 134 134 TYR TYR C . n 
E 5 135 SER 135 135 135 SER SER C . n 
E 5 136 PRO 136 136 136 PRO PRO C . n 
E 5 137 PRO 137 137 137 PRO PRO C . n 
E 5 138 GLY 138 138 138 GLY GLY C . n 
E 5 139 ALA 139 139 139 ALA ALA C . n 
E 5 140 GLY 140 140 140 GLY GLY C . n 
E 5 141 VAL 141 141 141 VAL VAL C . n 
E 5 142 PRO 142 142 142 PRO PRO C . n 
E 5 143 LYS 143 143 143 LYS LYS C . n 
E 5 144 ASN 144 144 144 ASN ASN C . n 
E 5 145 ARG 145 145 145 ARG ARG C . n 
E 5 146 LYS 146 146 146 LYS LYS C . n 
E 5 147 ASP 147 147 147 ASP ASP C . n 
E 5 148 ALA 148 148 148 ALA ALA C . n 
E 5 149 MET 149 149 149 MET MET C . n 
E 5 150 LEU 150 150 150 LEU LEU C . n 
E 5 151 GLY 151 151 151 GLY GLY C . n 
E 5 152 THR 152 152 152 THR THR C . n 
E 5 153 HIS 153 153 153 HIS HIS C . n 
E 5 154 VAL 154 154 154 VAL VAL C . n 
E 5 155 ILE 155 155 155 ILE ILE C . n 
E 5 156 TRP 156 156 156 TRP TRP C . n 
E 5 157 ASP 157 157 157 ASP ASP C . n 
E 5 158 VAL 158 158 158 VAL VAL C . n 
E 5 159 GLY 159 159 159 GLY GLY C . n 
E 5 160 LEU 160 160 160 LEU LEU C . n 
E 5 161 GLN 161 161 161 GLN GLN C . n 
E 5 162 SER 162 162 162 SER SER C . n 
E 5 163 SER 163 163 163 SER SER C . n 
E 5 164 CYS 164 164 164 CYS CYS C . n 
E 5 165 VAL 165 165 165 VAL VAL C . n 
E 5 166 LEU 166 166 166 LEU LEU C . n 
E 5 167 CYS 167 167 167 CYS CYS C . n 
E 5 168 VAL 168 168 168 VAL VAL C . n 
E 5 169 PRO 169 169 169 PRO PRO C . n 
E 5 170 TRP 170 170 170 TRP TRP C . n 
E 5 171 ILE 171 171 171 ILE ILE C . n 
E 5 172 SER 172 172 172 SER SER C . n 
E 5 173 GLN 173 173 ?   ?   ?   C . n 
E 5 174 THR 174 174 ?   ?   ?   C . n 
E 5 175 HIS 175 175 ?   ?   ?   C . n 
E 5 176 TYR 176 176 ?   ?   ?   C . n 
E 5 177 ARG 177 177 ?   ?   ?   C . n 
E 5 178 TYR 178 178 ?   ?   ?   C . n 
E 5 179 VAL 179 179 ?   ?   ?   C . n 
E 5 180 VAL 180 180 ?   ?   ?   C . n 
E 5 181 GLU 181 181 ?   ?   ?   C . n 
E 5 182 ASP 182 182 ?   ?   ?   C . n 
E 5 183 GLU 183 183 ?   ?   ?   C . n 
E 5 184 TYR 184 184 ?   ?   ?   C . n 
E 5 185 THR 185 185 ?   ?   ?   C . n 
E 5 186 ALA 186 186 186 ALA ALA C . n 
E 5 187 ALA 187 187 187 ALA ALA C . n 
E 5 188 GLY 188 188 188 GLY GLY C . n 
E 5 189 TYR 189 189 189 TYR TYR C . n 
E 5 190 VAL 190 190 190 VAL VAL C . n 
E 5 191 THR 191 191 191 THR THR C . n 
E 5 192 CYS 192 192 192 CYS CYS C . n 
E 5 193 TRP 193 193 193 TRP TRP C . n 
E 5 194 TYR 194 194 194 TYR TYR C . n 
E 5 195 GLN 195 195 195 GLN GLN C . n 
E 5 196 THR 196 196 196 THR THR C . n 
E 5 197 ASN 197 197 197 ASN ASN C . n 
E 5 198 ILE 198 198 198 ILE ILE C . n 
E 5 199 VAL 199 199 199 VAL VAL C . n 
E 5 200 VAL 200 200 200 VAL VAL C . n 
E 5 201 PRO 201 201 201 PRO PRO C . n 
E 5 202 ALA 202 202 202 ALA ALA C . n 
E 5 203 ASP 203 203 203 ASP ASP C . n 
E 5 204 VAL 204 204 204 VAL VAL C . n 
E 5 205 GLN 205 205 205 GLN GLN C . n 
E 5 206 SER 206 206 206 SER SER C . n 
E 5 207 SER 207 207 207 SER SER C . n 
E 5 208 CYS 208 208 208 CYS CYS C . n 
E 5 209 ASP 209 209 209 ASP ASP C . n 
E 5 210 ILE 210 210 210 ILE ILE C . n 
E 5 211 LEU 211 211 211 LEU LEU C . n 
E 5 212 CYS 212 212 212 CYS CYS C . n 
E 5 213 PHE 213 213 213 PHE PHE C . n 
E 5 214 VAL 214 214 214 VAL VAL C . n 
E 5 215 SER 215 215 215 SER SER C . n 
E 5 216 ALA 216 216 216 ALA ALA C . n 
E 5 217 CYS 217 217 217 CYS CYS C . n 
E 5 218 ASN 218 218 218 ASN ASN C . n 
E 5 219 ASP 219 219 219 ASP ASP C . n 
E 5 220 PHE 220 220 220 PHE PHE C . n 
E 5 221 SER 221 221 221 SER SER C . n 
E 5 222 VAL 222 222 222 VAL VAL C . n 
E 5 223 ARG 223 223 223 ARG ARG C . n 
E 5 224 MET 224 224 224 MET MET C . n 
E 5 225 LEU 225 225 225 LEU LEU C . n 
E 5 226 LYS 226 226 226 LYS LYS C . n 
E 5 227 ASP 227 227 227 ASP ASP C . n 
E 5 228 THR 228 228 228 THR THR C . n 
E 5 229 PRO 229 229 229 PRO PRO C . n 
E 5 230 PHE 230 230 230 PHE PHE C . n 
E 5 231 ILE 231 231 231 ILE ILE C . n 
E 5 232 ARG 232 232 232 ARG ARG C . n 
E 5 233 GLN 233 233 ?   ?   ?   C . n 
E 5 234 ASP 234 234 ?   ?   ?   C . n 
E 5 235 THR 235 235 ?   ?   ?   C . n 
E 5 236 PHE 236 236 ?   ?   ?   C . n 
E 5 237 TYR 237 237 ?   ?   ?   C . n 
E 5 238 GLN 238 238 ?   ?   ?   C . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              abing0811@xmu.edu.cn 
_pdbx_contact_author.name_first         Qingbing 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7516-9965 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     -0.80901699 -0.30901699 0.50000000  193.81546  0.50000000  -0.80901699 0.30901699  
0.00000    0.30901699  0.50000000  0.80901699  -507.41547 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  313.60001  0.80901700  0.30901699  -0.50000000 
119.78455  0.30901699  0.50000000  0.80901700  -193.81546 
3  'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901700  313.60000  0.50000000  -0.80901700 -0.30901700 
507.41547  0.80901699  0.30901700  0.50000000  -193.81546 
4  'point symmetry operation' ?     ?     -0.30901700 0.50000000  0.80901700  0.00000    -0.50000000 -0.80901699 0.30901700  
627.20001  0.80901700  -0.30901699 0.50000000  0.00000    
5  'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901700  -193.81546 -0.80901699 0.30901700  0.50000000  
313.60000  0.30901700  -0.50000000 0.80901699  119.78454  
6  'point symmetry operation' ?     ?     -0.80901699 0.30901700  0.50000001  313.60000  0.30901699  -0.50000000 0.80901699  
119.78454  0.49999999  0.80901700  0.30901699  -193.81546 
7  'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
8  'point symmetry operation' ?     ?     0.80901700  0.30901699  -0.50000000 119.78455  0.30901699  0.50000000  0.80901699  
-193.81547 0.50000000  -0.80901700 0.30901699  313.60001  
9  'point symmetry operation' ?     ?     0.50000000  -0.80901700 -0.30901699 507.41547  0.80901699  0.30901699  0.50000000  
-193.81546 -0.30901700 -0.50000000 0.80901699  313.60001  
10 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901700  627.20001  0.80901699  -0.30901700 0.50000000  
0.00000    -0.30901700 0.50000000  0.80901699  0.00000    
11 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  627.20001  -0.80901700 0.30901699  -0.49999999 
627.20002  0.30901700  -0.50000001 -0.80901699 627.20002  
12 'point symmetry operation' ?     ?     -0.80901700 0.30901700  0.50000000  313.60001  -0.30901700 0.50000000  -0.80901699 
507.41547  -0.50000000 -0.80901700 -0.30901699 821.01548  
13 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
627.20002  -1.00000000 0.00000000  0.00000000  627.20001  
14 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 119.78455  -0.30901699 -0.50000000 -0.80901700 
821.01548  -0.50000000 0.80901700  -0.30901699 313.60001  
15 'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901700 507.41547  -0.80901699 -0.30901700 -0.50000000 
821.01548  0.30901700  0.50000000  -0.80901699 313.60001  
16 'point symmetry operation' ?     ?     0.30901699  0.49999999  -0.80901700 313.60001  0.50000001  -0.80901699 -0.30901700 
507.41547  -0.80901699 -0.30901699 -0.50000000 821.01548  
17 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901700 627.20002  -0.50000000 -0.80901699 0.30901699  
627.20001  -0.80901699 0.30901700  -0.50000000 627.20002  
18 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901700 821.01548  -0.80901700 0.30901699  0.50000000  
313.60001  -0.30901699 0.50000000  -0.80901699 507.41548  
19 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  627.20001  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 627.20002  
20 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901700 313.60001  0.80901699  0.30901700  -0.50000000 
119.78455  -0.30901700 -0.50000000 -0.80901699 821.01548  
21 'point symmetry operation' ?     ?     -0.49999999 -0.80901700 -0.30901699 821.01548  0.80901699  -0.30901700 -0.50000001 
313.60001  0.30901699  -0.50000000 0.80901699  119.78454  
22 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  627.20001  0.00000000  -1.00000000 0.00000000  
627.20002  0.00000000  0.00000000  1.00000000  0.00000    
23 'point symmetry operation' ?     ?     -0.50000000 0.80901700  -0.30901699 313.60001  -0.80901700 -0.30901699 0.50000000  
507.41547  0.30901699  0.50000000  0.80901699  -193.81546 
24 'point symmetry operation' ?     ?     0.30901700  0.50000000  -0.80901699 313.60001  -0.50000000 0.80901700  0.30901699  
119.78454  0.80901699  0.30901699  0.50000000  -193.81546 
25 'point symmetry operation' ?     ?     0.30901700  -0.50000000 -0.80901699 627.20002  0.50000000  0.80901699  -0.30901700 
0.00000    0.80901699  -0.30901700 0.50000000  0.00000    
26 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 627.20002  -1.00000000 0.00000000  0.00000000  
627.20002  0.00000000  1.00000000  0.00000000  0.00000    
27 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901700 821.01548  -0.50000000 0.80901699  -0.30901699 
313.60001  0.80901700  0.30901699  -0.50000000 119.78455  
28 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 -0.50000000 821.01548  0.30901699  0.50000000  -0.80901700 
313.60001  0.50000000  -0.80901700 -0.30901700 507.41548  
29 'point symmetry operation' ?     ?     -0.80901700 0.30901699  -0.50000000 627.20002  0.30901700  -0.50000000 -0.80901700 
627.20002  -0.50000000 -0.80901699 0.30901700  627.20001  
30 'point symmetry operation' ?     ?     -0.30901700 0.50000000  -0.80901699 507.41547  -0.50000000 -0.80901699 -0.30901700 
821.01548  -0.80901699 0.30901700  0.50000000  313.60001  
31 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  -193.81546 -0.30901699 -0.49999999 0.80901700  
313.60000  0.50000001  -0.80901699 -0.30901700 507.41547  
32 'point symmetry operation' ?     ?     0.80901699  -0.30901700 0.50000000  0.00000    -0.30901699 0.50000000  0.80901700  
0.00000    -0.50000000 -0.80901699 0.30901699  627.20002  
33 'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  119.78454  0.50000000  0.80901699  0.30901700  
-193.81546 -0.80901700 0.30901699  0.50000000  313.60001  
34 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
35 'point symmetry operation' ?     ?     0.30901700  0.50000000  0.80901699  -193.81547 0.50000000  -0.80901699 0.30901700  
313.60001  0.80901699  0.30901700  -0.50000000 119.78455  
36 'point symmetry operation' ?     ?     -0.30901700 0.50000001  0.80901699  0.00000    0.50000000  0.80901699  -0.30901699 
0.00000    -0.80901700 0.30901699  -0.49999999 627.20002  
37 'point symmetry operation' ?     ?     0.50000000  0.80901700  0.30901699  -193.81546 0.80901700  -0.30901700 -0.50000000 
313.60001  -0.30901700 0.50000000  -0.80901699 507.41547  
38 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
627.20001  0.00000000  0.00000000  -1.00000000 627.20002  
39 'point symmetry operation' ?     ?     0.50000000  -0.80901700 0.30901699  313.60001  -0.80901699 -0.30901699 0.50000000  
507.41547  -0.30901699 -0.50000000 -0.80901700 821.01548  
40 'point symmetry operation' ?     ?     -0.30901700 -0.50000000 0.80901699  313.60001  -0.50000000 0.80901699  0.30901700  
119.78454  -0.80901699 -0.30901700 -0.50000000 821.01548  
41 'point symmetry operation' ?     ?     -0.50000001 0.80901699  0.30901700  119.78454  -0.80901699 -0.30901699 -0.50000000 
821.01548  -0.30901699 -0.49999999 0.80901700  313.60000  
42 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000    -0.80901699 0.30901700  -0.50000000 
627.20001  -0.30901699 0.50000000  0.80901700  0.00000    
43 'point symmetry operation' ?     ?     0.80901700  -0.30901699 -0.50000000 313.60001  -0.30901699 0.50000000  -0.80901699 
507.41547  0.50000000  0.80901699  0.30901700  -193.81546 
44 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  627.20001  0.00000000  0.00000000  -1.00000000 
627.20002  1.00000000  0.00000000  0.00000000  0.00000    
45 'point symmetry operation' ?     ?     -0.80901699 -0.30901700 0.50000000  507.41547  -0.30901700 -0.50000000 -0.80901699 
821.01548  0.50000000  -0.80901699 0.30901700  313.60001  
46 'point symmetry operation' ?     ?     0.80901700  -0.30901699 0.49999999  0.00000    0.30901700  -0.50000001 -0.80901699 
627.20002  0.50000000  0.80901699  -0.30901699 0.00000    
47 'point symmetry operation' ?     ?     0.30901700  -0.50000000 0.80901699  119.78454  -0.50000000 -0.80901700 -0.30901699 
821.01548  0.80901700  -0.30901700 -0.50000000 313.60001  
48 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
627.20001  0.00000000  -1.00000000 0.00000000  627.20002  
49 'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901700  -193.81546 -0.50000000 0.80901700  -0.30901699 
313.60001  -0.80901699 -0.30901699 0.50000000  507.41547  
50 'point symmetry operation' ?     ?     0.80901699  0.30901700  0.50000000  -193.81546 0.30901700  0.50000000  -0.80901699 
313.60001  -0.50000000 0.80901699  0.30901700  119.78454  
51 'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 507.41547  0.49999999  0.80901700  0.30901699  
-193.81546 0.80901699  -0.30901700 -0.50000001 313.60001  
52 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 627.20002  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  627.20002  
53 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 821.01548  0.50000000  -0.80901700 0.30901699  
313.60001  -0.80901700 -0.30901699 0.50000000  507.41547  
54 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 821.01548  -0.30901700 -0.50000000 0.80901699  
313.60001  -0.50000000 0.80901700  0.30901699  119.78454  
55 'point symmetry operation' ?     ?     -0.80901699 0.30901700  -0.50000000 627.20001  -0.30901700 0.50000000  0.80901699  
0.00000    0.50000000  0.80901699  -0.30901700 0.00000    
56 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  627.20002  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  627.20002  
57 'point symmetry operation' ?     ?     -0.80901700 -0.30901699 0.50000000  507.41547  0.30901699  0.50000000  0.80901700  
-193.81546 -0.50000000 0.80901699  -0.30901699 313.60001  
58 'point symmetry operation' ?     ?     -0.50000000 0.80901700  0.30901700  119.78454  0.80901699  0.30901700  0.50000000  
-193.81546 0.30901699  0.50000000  -0.80901700 313.60001  
59 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901700 0.00000    0.80901700  -0.30901699 0.50000000  
0.00000    0.30901700  -0.50000000 -0.80901700 627.20002  
60 'point symmetry operation' ?     ?     0.80901699  -0.30901700 -0.50000000 313.60001  0.30901700  -0.50000000 0.80901699  
119.78454  -0.50000000 -0.80901699 -0.30901700 821.01548  
# 
_pdbx_point_symmetry.entry_id             7X4K 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2022-09-28 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.14_3259: 
_software.pdbx_ordinal           1 
# 
_em_3d_fitting.entry_id          7X4K 
_em_3d_fitting.id                1 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_protocol      ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.method            ? 
# 
_em_3d_reconstruction.entry_id                    7X4K 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.num_particles               2038 
_em_3d_reconstruction.resolution                  3.82 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.symmetry_type               POINT 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.magnification_calibration   ? 
# 
_em_buffer.id            1 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.details              ? 
_em_entity_assembly.name                 
;Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (classified from CVB1 mature virion in complex with 8A10 and 9A3)
;
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
# 
_em_imaging.id                              1 
_em_imaging.entry_id                        7X4K 
_em_imaging.accelerating_voltage            300 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.cryogen                         ? 
_em_imaging.details                         ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.microscope_model                'FEI TECNAI F30' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_max             2900 
_em_imaging.nominal_defocus_min             1100 
_em_imaging.nominal_magnification           ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.specimen_id                     1 
_em_imaging.citation_id                     ? 
_em_imaging.date                            ? 
_em_imaging.temperature                     ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.astigmatism                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.specimen_holder_type            ? 
# 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.details               ? 
_em_vitrification.humidity              ? 
_em_vitrification.instrument            ? 
_em_vitrification.entry_id              7X4K 
_em_vitrification.citation_id           ? 
_em_vitrification.method                ? 
_em_vitrification.temp                  ? 
_em_vitrification.time_resolved_state   ? 
# 
_em_experiment.entry_id                7X4K 
_em_experiment.id                      1 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.entity_assembly_id      1 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             B 
_pdbx_validate_rmsd_angle.auth_comp_id_1             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_1              251 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             B 
_pdbx_validate_rmsd_angle.auth_comp_id_2             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_2              251 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             SG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             B 
_pdbx_validate_rmsd_angle.auth_comp_id_3             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_3              251 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                121.63 
_pdbx_validate_rmsd_angle.angle_target_value         114.20 
_pdbx_validate_rmsd_angle.angle_deviation            7.43 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU H 48  ? ? -92.68  -60.63  
2  1 THR L 52  ? ? 64.98   -6.97   
3  1 ARG A 70  ? ? -128.39 -168.72 
4  1 LYS A 85  ? ? -142.33 25.50   
5  1 ALA A 129 ? ? -172.80 -168.68 
6  1 SER A 131 ? ? 60.36   66.20   
7  1 ASN A 173 ? ? -125.53 -169.74 
8  1 ASN A 208 ? ? 57.60   72.89   
9  1 THR A 209 ? ? -63.65  5.40    
10 1 VAL A 246 ? ? 55.36   79.61   
11 1 TYR B 41  ? ? -79.83  -168.74 
12 1 ASN B 74  ? ? -94.15  51.32   
13 1 ALA B 76  ? ? -120.29 -50.83  
14 1 PRO B 83  ? ? -87.81  41.53   
15 1 ASP B 84  ? ? -133.33 -33.67  
16 1 ASP B 150 ? ? 39.92   39.52   
17 1 THR C 11  ? ? -96.69  58.56   
18 1 THR C 58  ? ? 38.43   34.29   
19 1 GLU C 59  ? ? 64.15   -2.42   
20 1 SER C 63  ? ? -94.56  50.58   
21 1 SER C 163 ? ? -160.72 116.35  
22 1 CYS C 217 ? ? -95.47  31.75   
23 1 ASP C 219 ? ? -143.12 46.25   
24 1 MET C 224 ? ? 60.77   71.15   
25 1 PHE C 230 ? ? -93.89  51.95   
# 
_pdbx_unobs_or_zero_occ_atoms.id               1 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id     L 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id     ALA 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id      101 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id     CB 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id     ? 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id    B 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id    ALA 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id     101 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id    CB 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 L GLU 1   ? B GLU 1   
2   1 Y 1 A GLY 1   ? C GLY 1   
3   1 Y 1 A PRO 2   ? C PRO 2   
4   1 Y 1 A VAL 3   ? C VAL 3   
5   1 Y 1 A GLU 4   ? C GLU 4   
6   1 Y 1 A GLU 5   ? C GLU 5   
7   1 Y 1 A SER 6   ? C SER 6   
8   1 Y 1 A VAL 7   ? C VAL 7   
9   1 Y 1 A ASP 8   ? C ASP 8   
10  1 Y 1 A ARG 9   ? C ARG 9   
11  1 Y 1 A ALA 10  ? C ALA 10  
12  1 Y 1 A VAL 11  ? C VAL 11  
13  1 Y 1 A ALA 12  ? C ALA 12  
14  1 Y 1 A ARG 13  ? C ARG 13  
15  1 Y 1 A VAL 14  ? C VAL 14  
16  1 Y 1 A ALA 15  ? C ALA 15  
17  1 Y 1 A ASP 16  ? C ASP 16  
18  1 Y 1 A THR 17  ? C THR 17  
19  1 Y 1 A ILE 18  ? C ILE 18  
20  1 Y 1 A SER 19  ? C SER 19  
21  1 Y 1 A SER 20  ? C SER 20  
22  1 Y 1 A ARG 21  ? C ARG 21  
23  1 Y 1 A PRO 22  ? C PRO 22  
24  1 Y 1 A THR 23  ? C THR 23  
25  1 Y 1 A ASN 24  ? C ASN 24  
26  1 Y 1 A SER 25  ? C SER 25  
27  1 Y 1 A GLU 26  ? C GLU 26  
28  1 Y 1 A SER 27  ? C SER 27  
29  1 Y 1 A ILE 28  ? C ILE 28  
30  1 Y 1 A PRO 29  ? C PRO 29  
31  1 Y 1 A ALA 30  ? C ALA 30  
32  1 Y 1 A LEU 31  ? C LEU 31  
33  1 Y 1 A THR 32  ? C THR 32  
34  1 Y 1 A ALA 33  ? C ALA 33  
35  1 Y 1 A ALA 34  ? C ALA 34  
36  1 Y 1 A GLU 35  ? C GLU 35  
37  1 Y 1 A THR 36  ? C THR 36  
38  1 Y 1 A GLY 37  ? C GLY 37  
39  1 Y 1 A HIS 38  ? C HIS 38  
40  1 Y 1 A THR 39  ? C THR 39  
41  1 Y 1 A SER 40  ? C SER 40  
42  1 Y 1 A GLN 41  ? C GLN 41  
43  1 Y 1 A VAL 42  ? C VAL 42  
44  1 Y 1 A VAL 43  ? C VAL 43  
45  1 Y 1 A PRO 44  ? C PRO 44  
46  1 Y 1 A SER 45  ? C SER 45  
47  1 Y 1 A ASP 46  ? C ASP 46  
48  1 Y 1 A THR 47  ? C THR 47  
49  1 Y 1 A MET 48  ? C MET 48  
50  1 Y 1 A GLN 49  ? C GLN 49  
51  1 Y 1 A THR 50  ? C THR 50  
52  1 Y 1 A ARG 51  ? C ARG 51  
53  1 Y 1 A HIS 52  ? C HIS 52  
54  1 Y 1 A VAL 53  ? C VAL 53  
55  1 Y 1 A LYS 54  ? C LYS 54  
56  1 Y 1 A ASN 55  ? C ASN 55  
57  1 Y 1 A TYR 56  ? C TYR 56  
58  1 Y 1 A HIS 57  ? C HIS 57  
59  1 Y 1 A GLN 198 ? C GLN 198 
60  1 Y 1 A PHE 199 ? C PHE 199 
61  1 Y 1 A SER 200 ? C SER 200 
62  1 Y 1 A ARG 201 ? C ARG 201 
63  1 Y 1 A ASN 202 ? C ASN 202 
64  1 Y 1 A GLY 203 ? C GLY 203 
65  1 Y 1 A THR 277 ? C THR 277 
66  1 Y 1 A THR 278 ? C THR 278 
67  1 Y 1 B SER 1   ? D SER 1   
68  1 Y 1 B PRO 2   ? D PRO 2   
69  1 Y 1 B SER 3   ? D SER 3   
70  1 Y 1 B ALA 4   ? D ALA 4   
71  1 Y 1 B GLU 5   ? D GLU 5   
72  1 Y 1 B GLU 6   ? D GLU 6   
73  1 Y 1 B CYS 7   ? D CYS 7   
74  1 Y 1 B GLY 8   ? D GLY 8   
75  1 Y 1 B TYR 9   ? D TYR 9   
76  1 Y 1 B SER 10  ? D SER 10  
77  1 Y 1 B ASP 11  ? D ASP 11  
78  1 Y 1 B ARG 12  ? D ARG 12  
79  1 Y 1 B VAL 13  ? D VAL 13  
80  1 Y 1 B GLU 27  ? D GLU 27  
81  1 Y 1 B CYS 28  ? D CYS 28  
82  1 Y 1 B ALA 29  ? D ALA 29  
83  1 Y 1 B LYS 43  ? D LYS 43  
84  1 Y 1 B ASP 44  ? D ASP 44  
85  1 Y 1 B ASN 45  ? D ASN 45  
86  1 Y 1 B GLU 46  ? D GLU 46  
87  1 Y 1 B ALA 47  ? D ALA 47  
88  1 Y 1 B THR 48  ? D THR 48  
89  1 Y 1 B ALA 49  ? D ALA 49  
90  1 Y 1 B GLU 50  ? D GLU 50  
91  1 Y 1 B ARG 258 ? D ARG 258 
92  1 Y 1 B LEU 259 ? D LEU 259 
93  1 Y 1 B ALA 260 ? D ALA 260 
94  1 Y 1 B SER 261 ? D SER 261 
95  1 Y 1 B ASN 262 ? D ASN 262 
96  1 Y 1 B GLN 263 ? D GLN 263 
97  1 Y 1 C GLN 173 ? E GLN 173 
98  1 Y 1 C THR 174 ? E THR 174 
99  1 Y 1 C HIS 175 ? E HIS 175 
100 1 Y 1 C TYR 176 ? E TYR 176 
101 1 Y 1 C ARG 177 ? E ARG 177 
102 1 Y 1 C TYR 178 ? E TYR 178 
103 1 Y 1 C VAL 179 ? E VAL 179 
104 1 Y 1 C VAL 180 ? E VAL 180 
105 1 Y 1 C GLU 181 ? E GLU 181 
106 1 Y 1 C ASP 182 ? E ASP 182 
107 1 Y 1 C GLU 183 ? E GLU 183 
108 1 Y 1 C TYR 184 ? E TYR 184 
109 1 Y 1 C THR 185 ? E THR 185 
110 1 Y 1 C GLN 233 ? E GLN 233 
111 1 Y 1 C ASP 234 ? E ASP 234 
112 1 Y 1 C THR 235 ? E THR 235 
113 1 Y 1 C PHE 236 ? E PHE 236 
114 1 Y 1 C TYR 237 ? E TYR 237 
115 1 Y 1 C GLN 238 ? E GLN 238 
# 
_em_ctf_correction.id                       1 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
_em_ctf_correction.details                  ? 
# 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.ncbi_tax_id          12071 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organism             'Coxsackievirus B1' 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.ncbi_tax_id          10029 
_em_entity_assembly_recombinant.organism             'Cricetulus griseus' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
_em_image_processing.details              ? 
# 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       INTEGRATING 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
# 
loop_
_em_software.id 
_em_software.category 
_em_software.details 
_em_software.name 
_em_software.version 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
1  'PARTICLE SELECTION'       ? ? ? 1 ? ? 
2  'IMAGE ACQUISITION'        ? ? ? ? ? 1 
3  MASKING                    ? ? ? ? ? ? 
4  'CTF CORRECTION'           ? ? ? 1 ? ? 
5  'LAYERLINE INDEXING'       ? ? ? ? ? ? 
6  'DIFFRACTION INDEXING'     ? ? ? ? ? ? 
7  'MODEL FITTING'            ? ? ? ? ? ? 
8  'MODEL REFINEMENT'         ? ? ? ? ? ? 
9  OTHER                      ? ? ? ? ? ? 
10 'INITIAL EULER ASSIGNMENT' ? ? ? 1 ? ? 
11 'FINAL EULER ASSIGNMENT'   ? ? ? 1 ? ? 
12 CLASSIFICATION             ? ? ? 1 ? ? 
13 RECONSTRUCTION             ? ? ? 1 ? ? 
# 
_em_specimen.id                      1 
_em_specimen.experiment_id           1 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
