data_7XZ5
# 
_entry.id   7XZ5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.359 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   7XZ5         pdb_00007xz5 10.2210/pdb7xz5/pdb 
WWPDB D_1300029961 ?            ?                   
EMDB  EMD-33525    ?            ?                   
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'GPR119-Gs-LPC complex' 
_pdbx_database_related.db_id          EMD-33525 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        7XZ5 
_pdbx_database_status.recvd_initial_deposition_date   2022-06-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xu, P.'    1 ? 
'Huang, S.' 2 ? 
'Jiang, Y.' 3 ? 
'Xu, H.E.'  4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nat.Struct.Mol.Biol. 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1545-9985 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119.' 
_citation.year                      2022 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41594-022-00816-5 
_citation.pdbx_database_id_PubMed   35970999 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xu, P.'    1  0000-0003-3590-4037 
primary 'Huang, S.' 2  0000-0001-5653-0260 
primary 'Guo, S.'   3  0000-0002-8086-5092 
primary 'Yun, Y.'   4  ?                   
primary 'Cheng, X.' 5  0000-0003-3735-645X 
primary 'He, X.'    6  0000-0001-7813-5480 
primary 'Cai, P.'   7  ?                   
primary 'Lan, Y.'   8  ?                   
primary 'Zhou, H.'  9  0000-0001-7006-4737 
primary 'Jiang, H.' 10 0000-0003-0656-6315 
primary 'Jiang, Y.' 11 0000-0002-0723-1413 
primary 'Xie, X.'   12 0000-0003-2314-4800 
primary 'Xu, H.E.'  13 0000-0002-6829-8144 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     7XZ5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         7XZ5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Guanine nucleotide-binding protein G(s) subunit alpha isoforms short'                                    
45699.434 1 ? ? ? ? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'                                        
37915.496 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'                                       
7861.143  1 ? ? ? ? 
4 polymer     man Nanobody35                                                                                                
15271.938 1 ? ? ? ? 
5 polymer     man 'Soluble cytochrome b562,Glucose-dependent insulinotropic receptor'                                       
53785.129 1 ? ? ? ? 
6 non-polymer syn '(4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide' 
522.675   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 'Transducin beta chain 1'                         
3 'G gamma-I'                                       
5 'Cytochrome b-562,G-protein coupled receptor 119' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKNTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQAALKLFDSIWNNKWLRDTSVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCSVDTENIRRVFNDCRDIIQRMHLRQYELL
;
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKNTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQAALKLFDSIWNNKWLRDTSVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCSVDTENIRRVFNDCRDIIQRMHLRQYELL
;
A ? 
2 'polypeptide(L)' no no 
;MGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWN
;
;MGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQ
DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN
QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF
PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV
SCLGVTDDGMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
4 'polypeptide(L)' no no 
;MQVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTL
YLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSSHHHHHHEPEA
;
;MQVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTL
YLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSSHHHHHHEPEA
;
N ? 
5 'polypeptide(L)' no no 
;DYKDDDDAKLQTMHHHHHHHHHHHHHHHADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKS
PDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLASENLYFQGGGGGSGTMESSFSFGVI
LAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAA
ASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLS
CVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVA
CQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISS
SEFDG
;
;DYKDDDDAKLQTMHHHHHHHHHHHHHHHADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKS
PDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLASENLYFQGGGGGSGTMESSFSFGVI
LAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAA
ASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLS
CVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVA
CQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISS
SEFDG
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   LEU n 
1 5   GLY n 
1 6   ASN n 
1 7   SER n 
1 8   LYS n 
1 9   THR n 
1 10  GLU n 
1 11  ASP n 
1 12  GLN n 
1 13  ARG n 
1 14  ASN n 
1 15  GLU n 
1 16  GLU n 
1 17  LYS n 
1 18  ALA n 
1 19  GLN n 
1 20  ARG n 
1 21  GLU n 
1 22  ALA n 
1 23  ASN n 
1 24  LYS n 
1 25  LYS n 
1 26  ILE n 
1 27  GLU n 
1 28  LYS n 
1 29  GLN n 
1 30  LEU n 
1 31  GLN n 
1 32  LYS n 
1 33  ASP n 
1 34  LYS n 
1 35  GLN n 
1 36  VAL n 
1 37  TYR n 
1 38  ARG n 
1 39  ALA n 
1 40  THR n 
1 41  HIS n 
1 42  ARG n 
1 43  LEU n 
1 44  LEU n 
1 45  LEU n 
1 46  LEU n 
1 47  GLY n 
1 48  ALA n 
1 49  GLY n 
1 50  GLU n 
1 51  SER n 
1 52  GLY n 
1 53  LYS n 
1 54  ASN n 
1 55  THR n 
1 56  ILE n 
1 57  VAL n 
1 58  LYS n 
1 59  GLN n 
1 60  MET n 
1 61  ARG n 
1 62  ILE n 
1 63  LEU n 
1 64  HIS n 
1 65  VAL n 
1 66  ASN n 
1 67  GLY n 
1 68  PHE n 
1 69  ASN n 
1 70  GLY n 
1 71  GLU n 
1 72  GLY n 
1 73  GLY n 
1 74  GLU n 
1 75  GLU n 
1 76  ASP n 
1 77  PRO n 
1 78  GLN n 
1 79  ALA n 
1 80  ALA n 
1 81  ARG n 
1 82  SER n 
1 83  ASN n 
1 84  SER n 
1 85  ASP n 
1 86  GLY n 
1 87  GLU n 
1 88  LYS n 
1 89  ALA n 
1 90  THR n 
1 91  LYS n 
1 92  VAL n 
1 93  GLN n 
1 94  ASP n 
1 95  ILE n 
1 96  LYS n 
1 97  ASN n 
1 98  ASN n 
1 99  LEU n 
1 100 LYS n 
1 101 GLU n 
1 102 ALA n 
1 103 ILE n 
1 104 GLU n 
1 105 THR n 
1 106 ILE n 
1 107 VAL n 
1 108 ALA n 
1 109 ALA n 
1 110 MET n 
1 111 SER n 
1 112 ASN n 
1 113 LEU n 
1 114 VAL n 
1 115 PRO n 
1 116 PRO n 
1 117 VAL n 
1 118 GLU n 
1 119 LEU n 
1 120 ALA n 
1 121 ASN n 
1 122 PRO n 
1 123 GLU n 
1 124 ASN n 
1 125 GLN n 
1 126 PHE n 
1 127 ARG n 
1 128 VAL n 
1 129 ASP n 
1 130 TYR n 
1 131 ILE n 
1 132 LEU n 
1 133 SER n 
1 134 VAL n 
1 135 MET n 
1 136 ASN n 
1 137 VAL n 
1 138 PRO n 
1 139 ASP n 
1 140 PHE n 
1 141 ASP n 
1 142 PHE n 
1 143 PRO n 
1 144 PRO n 
1 145 GLU n 
1 146 PHE n 
1 147 TYR n 
1 148 GLU n 
1 149 HIS n 
1 150 ALA n 
1 151 LYS n 
1 152 ALA n 
1 153 LEU n 
1 154 TRP n 
1 155 GLU n 
1 156 ASP n 
1 157 GLU n 
1 158 GLY n 
1 159 VAL n 
1 160 ARG n 
1 161 ALA n 
1 162 CYS n 
1 163 TYR n 
1 164 GLU n 
1 165 ARG n 
1 166 SER n 
1 167 ASN n 
1 168 GLU n 
1 169 TYR n 
1 170 GLN n 
1 171 LEU n 
1 172 ILE n 
1 173 ASP n 
1 174 CYS n 
1 175 ALA n 
1 176 GLN n 
1 177 TYR n 
1 178 PHE n 
1 179 LEU n 
1 180 ASP n 
1 181 LYS n 
1 182 ILE n 
1 183 ASP n 
1 184 VAL n 
1 185 ILE n 
1 186 LYS n 
1 187 GLN n 
1 188 ALA n 
1 189 ASP n 
1 190 TYR n 
1 191 VAL n 
1 192 PRO n 
1 193 SER n 
1 194 ASP n 
1 195 GLN n 
1 196 ASP n 
1 197 LEU n 
1 198 LEU n 
1 199 ARG n 
1 200 CYS n 
1 201 ARG n 
1 202 VAL n 
1 203 LEU n 
1 204 THR n 
1 205 SER n 
1 206 GLY n 
1 207 ILE n 
1 208 PHE n 
1 209 GLU n 
1 210 THR n 
1 211 LYS n 
1 212 PHE n 
1 213 GLN n 
1 214 VAL n 
1 215 ASP n 
1 216 LYS n 
1 217 VAL n 
1 218 ASN n 
1 219 PHE n 
1 220 HIS n 
1 221 MET n 
1 222 PHE n 
1 223 ASP n 
1 224 VAL n 
1 225 GLY n 
1 226 ALA n 
1 227 GLN n 
1 228 ARG n 
1 229 ASP n 
1 230 GLU n 
1 231 ARG n 
1 232 ARG n 
1 233 LYS n 
1 234 TRP n 
1 235 ILE n 
1 236 GLN n 
1 237 CYS n 
1 238 PHE n 
1 239 ASN n 
1 240 ASP n 
1 241 VAL n 
1 242 THR n 
1 243 ALA n 
1 244 ILE n 
1 245 ILE n 
1 246 PHE n 
1 247 VAL n 
1 248 VAL n 
1 249 ALA n 
1 250 SER n 
1 251 SER n 
1 252 SER n 
1 253 TYR n 
1 254 ASN n 
1 255 MET n 
1 256 VAL n 
1 257 ILE n 
1 258 ARG n 
1 259 GLU n 
1 260 ASP n 
1 261 ASN n 
1 262 GLN n 
1 263 THR n 
1 264 ASN n 
1 265 ARG n 
1 266 LEU n 
1 267 GLN n 
1 268 ALA n 
1 269 ALA n 
1 270 LEU n 
1 271 LYS n 
1 272 LEU n 
1 273 PHE n 
1 274 ASP n 
1 275 SER n 
1 276 ILE n 
1 277 TRP n 
1 278 ASN n 
1 279 ASN n 
1 280 LYS n 
1 281 TRP n 
1 282 LEU n 
1 283 ARG n 
1 284 ASP n 
1 285 THR n 
1 286 SER n 
1 287 VAL n 
1 288 ILE n 
1 289 LEU n 
1 290 PHE n 
1 291 LEU n 
1 292 ASN n 
1 293 LYS n 
1 294 GLN n 
1 295 ASP n 
1 296 LEU n 
1 297 LEU n 
1 298 ALA n 
1 299 GLU n 
1 300 LYS n 
1 301 VAL n 
1 302 LEU n 
1 303 ALA n 
1 304 GLY n 
1 305 LYS n 
1 306 SER n 
1 307 LYS n 
1 308 ILE n 
1 309 GLU n 
1 310 ASP n 
1 311 TYR n 
1 312 PHE n 
1 313 PRO n 
1 314 GLU n 
1 315 PHE n 
1 316 ALA n 
1 317 ARG n 
1 318 TYR n 
1 319 THR n 
1 320 THR n 
1 321 PRO n 
1 322 GLU n 
1 323 ASP n 
1 324 ALA n 
1 325 THR n 
1 326 PRO n 
1 327 GLU n 
1 328 PRO n 
1 329 GLY n 
1 330 GLU n 
1 331 ASP n 
1 332 PRO n 
1 333 ARG n 
1 334 VAL n 
1 335 THR n 
1 336 ARG n 
1 337 ALA n 
1 338 LYS n 
1 339 TYR n 
1 340 PHE n 
1 341 ILE n 
1 342 ARG n 
1 343 ASP n 
1 344 GLU n 
1 345 PHE n 
1 346 LEU n 
1 347 ARG n 
1 348 ILE n 
1 349 SER n 
1 350 THR n 
1 351 ALA n 
1 352 SER n 
1 353 GLY n 
1 354 ASP n 
1 355 GLY n 
1 356 ARG n 
1 357 HIS n 
1 358 TYR n 
1 359 CYS n 
1 360 TYR n 
1 361 PRO n 
1 362 HIS n 
1 363 PHE n 
1 364 THR n 
1 365 CYS n 
1 366 SER n 
1 367 VAL n 
1 368 ASP n 
1 369 THR n 
1 370 GLU n 
1 371 ASN n 
1 372 ILE n 
1 373 ARG n 
1 374 ARG n 
1 375 VAL n 
1 376 PHE n 
1 377 ASN n 
1 378 ASP n 
1 379 CYS n 
1 380 ARG n 
1 381 ASP n 
1 382 ILE n 
1 383 ILE n 
1 384 GLN n 
1 385 ARG n 
1 386 MET n 
1 387 HIS n 
1 388 LEU n 
1 389 ARG n 
1 390 GLN n 
1 391 TYR n 
1 392 GLU n 
1 393 LEU n 
1 394 LEU n 
2 1   MET n 
2 2   GLY n 
2 3   SER n 
2 4   LEU n 
2 5   LEU n 
2 6   GLN n 
2 7   SER n 
2 8   GLU n 
2 9   LEU n 
2 10  ASP n 
2 11  GLN n 
2 12  LEU n 
2 13  ARG n 
2 14  GLN n 
2 15  GLU n 
2 16  ALA n 
2 17  GLU n 
2 18  GLN n 
2 19  LEU n 
2 20  LYS n 
2 21  ASN n 
2 22  GLN n 
2 23  ILE n 
2 24  ARG n 
2 25  ASP n 
2 26  ALA n 
2 27  ARG n 
2 28  LYS n 
2 29  ALA n 
2 30  CYS n 
2 31  ALA n 
2 32  ASP n 
2 33  ALA n 
2 34  THR n 
2 35  LEU n 
2 36  SER n 
2 37  GLN n 
2 38  ILE n 
2 39  THR n 
2 40  ASN n 
2 41  ASN n 
2 42  ILE n 
2 43  ASP n 
2 44  PRO n 
2 45  VAL n 
2 46  GLY n 
2 47  ARG n 
2 48  ILE n 
2 49  GLN n 
2 50  MET n 
2 51  ARG n 
2 52  THR n 
2 53  ARG n 
2 54  ARG n 
2 55  THR n 
2 56  LEU n 
2 57  ARG n 
2 58  GLY n 
2 59  HIS n 
2 60  LEU n 
2 61  ALA n 
2 62  LYS n 
2 63  ILE n 
2 64  TYR n 
2 65  ALA n 
2 66  MET n 
2 67  HIS n 
2 68  TRP n 
2 69  GLY n 
2 70  THR n 
2 71  ASP n 
2 72  SER n 
2 73  ARG n 
2 74  LEU n 
2 75  LEU n 
2 76  VAL n 
2 77  SER n 
2 78  ALA n 
2 79  SER n 
2 80  GLN n 
2 81  ASP n 
2 82  GLY n 
2 83  LYS n 
2 84  LEU n 
2 85  ILE n 
2 86  ILE n 
2 87  TRP n 
2 88  ASP n 
2 89  SER n 
2 90  TYR n 
2 91  THR n 
2 92  THR n 
2 93  ASN n 
2 94  LYS n 
2 95  VAL n 
2 96  HIS n 
2 97  ALA n 
2 98  ILE n 
2 99  PRO n 
2 100 LEU n 
2 101 ARG n 
2 102 SER n 
2 103 SER n 
2 104 TRP n 
2 105 VAL n 
2 106 MET n 
2 107 THR n 
2 108 CYS n 
2 109 ALA n 
2 110 TYR n 
2 111 ALA n 
2 112 PRO n 
2 113 SER n 
2 114 GLY n 
2 115 ASN n 
2 116 TYR n 
2 117 VAL n 
2 118 ALA n 
2 119 CYS n 
2 120 GLY n 
2 121 GLY n 
2 122 LEU n 
2 123 ASP n 
2 124 ASN n 
2 125 ILE n 
2 126 CYS n 
2 127 SER n 
2 128 ILE n 
2 129 TYR n 
2 130 ASN n 
2 131 LEU n 
2 132 LYS n 
2 133 THR n 
2 134 ARG n 
2 135 GLU n 
2 136 GLY n 
2 137 ASN n 
2 138 VAL n 
2 139 ARG n 
2 140 VAL n 
2 141 SER n 
2 142 ARG n 
2 143 GLU n 
2 144 LEU n 
2 145 ALA n 
2 146 GLY n 
2 147 HIS n 
2 148 THR n 
2 149 GLY n 
2 150 TYR n 
2 151 LEU n 
2 152 SER n 
2 153 CYS n 
2 154 CYS n 
2 155 ARG n 
2 156 PHE n 
2 157 LEU n 
2 158 ASP n 
2 159 ASP n 
2 160 ASN n 
2 161 GLN n 
2 162 ILE n 
2 163 VAL n 
2 164 THR n 
2 165 SER n 
2 166 SER n 
2 167 GLY n 
2 168 ASP n 
2 169 THR n 
2 170 THR n 
2 171 CYS n 
2 172 ALA n 
2 173 LEU n 
2 174 TRP n 
2 175 ASP n 
2 176 ILE n 
2 177 GLU n 
2 178 THR n 
2 179 GLY n 
2 180 GLN n 
2 181 GLN n 
2 182 THR n 
2 183 THR n 
2 184 THR n 
2 185 PHE n 
2 186 THR n 
2 187 GLY n 
2 188 HIS n 
2 189 THR n 
2 190 GLY n 
2 191 ASP n 
2 192 VAL n 
2 193 MET n 
2 194 SER n 
2 195 LEU n 
2 196 SER n 
2 197 LEU n 
2 198 ALA n 
2 199 PRO n 
2 200 ASP n 
2 201 THR n 
2 202 ARG n 
2 203 LEU n 
2 204 PHE n 
2 205 VAL n 
2 206 SER n 
2 207 GLY n 
2 208 ALA n 
2 209 CYS n 
2 210 ASP n 
2 211 ALA n 
2 212 SER n 
2 213 ALA n 
2 214 LYS n 
2 215 LEU n 
2 216 TRP n 
2 217 ASP n 
2 218 VAL n 
2 219 ARG n 
2 220 GLU n 
2 221 GLY n 
2 222 MET n 
2 223 CYS n 
2 224 ARG n 
2 225 GLN n 
2 226 THR n 
2 227 PHE n 
2 228 THR n 
2 229 GLY n 
2 230 HIS n 
2 231 GLU n 
2 232 SER n 
2 233 ASP n 
2 234 ILE n 
2 235 ASN n 
2 236 ALA n 
2 237 ILE n 
2 238 CYS n 
2 239 PHE n 
2 240 PHE n 
2 241 PRO n 
2 242 ASN n 
2 243 GLY n 
2 244 ASN n 
2 245 ALA n 
2 246 PHE n 
2 247 ALA n 
2 248 THR n 
2 249 GLY n 
2 250 SER n 
2 251 ASP n 
2 252 ASP n 
2 253 ALA n 
2 254 THR n 
2 255 CYS n 
2 256 ARG n 
2 257 LEU n 
2 258 PHE n 
2 259 ASP n 
2 260 LEU n 
2 261 ARG n 
2 262 ALA n 
2 263 ASP n 
2 264 GLN n 
2 265 GLU n 
2 266 LEU n 
2 267 MET n 
2 268 THR n 
2 269 TYR n 
2 270 SER n 
2 271 HIS n 
2 272 ASP n 
2 273 ASN n 
2 274 ILE n 
2 275 ILE n 
2 276 CYS n 
2 277 GLY n 
2 278 ILE n 
2 279 THR n 
2 280 SER n 
2 281 VAL n 
2 282 SER n 
2 283 PHE n 
2 284 SER n 
2 285 LYS n 
2 286 SER n 
2 287 GLY n 
2 288 ARG n 
2 289 LEU n 
2 290 LEU n 
2 291 LEU n 
2 292 ALA n 
2 293 GLY n 
2 294 TYR n 
2 295 ASP n 
2 296 ASP n 
2 297 PHE n 
2 298 ASN n 
2 299 CYS n 
2 300 ASN n 
2 301 VAL n 
2 302 TRP n 
2 303 ASP n 
2 304 ALA n 
2 305 LEU n 
2 306 LYS n 
2 307 ALA n 
2 308 ASP n 
2 309 ARG n 
2 310 ALA n 
2 311 GLY n 
2 312 VAL n 
2 313 LEU n 
2 314 ALA n 
2 315 GLY n 
2 316 HIS n 
2 317 ASP n 
2 318 ASN n 
2 319 ARG n 
2 320 VAL n 
2 321 SER n 
2 322 CYS n 
2 323 LEU n 
2 324 GLY n 
2 325 VAL n 
2 326 THR n 
2 327 ASP n 
2 328 ASP n 
2 329 GLY n 
2 330 MET n 
2 331 ALA n 
2 332 VAL n 
2 333 ALA n 
2 334 THR n 
2 335 GLY n 
2 336 SER n 
2 337 TRP n 
2 338 ASP n 
2 339 SER n 
2 340 PHE n 
2 341 LEU n 
2 342 LYS n 
2 343 ILE n 
2 344 TRP n 
2 345 ASN n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   MET n 
4 2   GLN n 
4 3   VAL n 
4 4   GLN n 
4 5   LEU n 
4 6   GLN n 
4 7   GLU n 
4 8   SER n 
4 9   GLY n 
4 10  GLY n 
4 11  GLY n 
4 12  LEU n 
4 13  VAL n 
4 14  GLN n 
4 15  PRO n 
4 16  GLY n 
4 17  GLY n 
4 18  SER n 
4 19  LEU n 
4 20  ARG n 
4 21  LEU n 
4 22  SER n 
4 23  CYS n 
4 24  ALA n 
4 25  ALA n 
4 26  SER n 
4 27  GLY n 
4 28  PHE n 
4 29  THR n 
4 30  PHE n 
4 31  SER n 
4 32  ASN n 
4 33  TYR n 
4 34  LYS n 
4 35  MET n 
4 36  ASN n 
4 37  TRP n 
4 38  VAL n 
4 39  ARG n 
4 40  GLN n 
4 41  ALA n 
4 42  PRO n 
4 43  GLY n 
4 44  LYS n 
4 45  GLY n 
4 46  LEU n 
4 47  GLU n 
4 48  TRP n 
4 49  VAL n 
4 50  SER n 
4 51  ASP n 
4 52  ILE n 
4 53  SER n 
4 54  GLN n 
4 55  SER n 
4 56  GLY n 
4 57  ALA n 
4 58  SER n 
4 59  ILE n 
4 60  SER n 
4 61  TYR n 
4 62  THR n 
4 63  GLY n 
4 64  SER n 
4 65  VAL n 
4 66  LYS n 
4 67  GLY n 
4 68  ARG n 
4 69  PHE n 
4 70  THR n 
4 71  ILE n 
4 72  SER n 
4 73  ARG n 
4 74  ASP n 
4 75  ASN n 
4 76  ALA n 
4 77  LYS n 
4 78  ASN n 
4 79  THR n 
4 80  LEU n 
4 81  TYR n 
4 82  LEU n 
4 83  GLN n 
4 84  MET n 
4 85  ASN n 
4 86  SER n 
4 87  LEU n 
4 88  LYS n 
4 89  PRO n 
4 90  GLU n 
4 91  ASP n 
4 92  THR n 
4 93  ALA n 
4 94  VAL n 
4 95  TYR n 
4 96  TYR n 
4 97  CYS n 
4 98  ALA n 
4 99  ARG n 
4 100 CYS n 
4 101 PRO n 
4 102 ALA n 
4 103 PRO n 
4 104 PHE n 
4 105 THR n 
4 106 ARG n 
4 107 ASP n 
4 108 CYS n 
4 109 PHE n 
4 110 ASP n 
4 111 VAL n 
4 112 THR n 
4 113 SER n 
4 114 THR n 
4 115 THR n 
4 116 TYR n 
4 117 ALA n 
4 118 TYR n 
4 119 ARG n 
4 120 GLY n 
4 121 GLN n 
4 122 GLY n 
4 123 THR n 
4 124 GLN n 
4 125 VAL n 
4 126 THR n 
4 127 VAL n 
4 128 SER n 
4 129 SER n 
4 130 HIS n 
4 131 HIS n 
4 132 HIS n 
4 133 HIS n 
4 134 HIS n 
4 135 HIS n 
4 136 GLU n 
4 137 PRO n 
4 138 GLU n 
4 139 ALA n 
5 1   ASP n 
5 2   TYR n 
5 3   LYS n 
5 4   ASP n 
5 5   ASP n 
5 6   ASP n 
5 7   ASP n 
5 8   ALA n 
5 9   LYS n 
5 10  LEU n 
5 11  GLN n 
5 12  THR n 
5 13  MET n 
5 14  HIS n 
5 15  HIS n 
5 16  HIS n 
5 17  HIS n 
5 18  HIS n 
5 19  HIS n 
5 20  HIS n 
5 21  HIS n 
5 22  HIS n 
5 23  HIS n 
5 24  HIS n 
5 25  HIS n 
5 26  HIS n 
5 27  HIS n 
5 28  HIS n 
5 29  ALA n 
5 30  ASP n 
5 31  LEU n 
5 32  GLU n 
5 33  ASP n 
5 34  ASN n 
5 35  TRP n 
5 36  GLU n 
5 37  THR n 
5 38  LEU n 
5 39  ASN n 
5 40  ASP n 
5 41  ASN n 
5 42  LEU n 
5 43  LYS n 
5 44  VAL n 
5 45  ILE n 
5 46  GLU n 
5 47  LYS n 
5 48  ALA n 
5 49  ASP n 
5 50  ASN n 
5 51  ALA n 
5 52  ALA n 
5 53  GLN n 
5 54  VAL n 
5 55  LYS n 
5 56  ASP n 
5 57  ALA n 
5 58  LEU n 
5 59  THR n 
5 60  LYS n 
5 61  MET n 
5 62  ARG n 
5 63  ALA n 
5 64  ALA n 
5 65  ALA n 
5 66  LEU n 
5 67  ASP n 
5 68  ALA n 
5 69  GLN n 
5 70  LYS n 
5 71  ALA n 
5 72  THR n 
5 73  PRO n 
5 74  PRO n 
5 75  LYS n 
5 76  LEU n 
5 77  GLU n 
5 78  ASP n 
5 79  LYS n 
5 80  SER n 
5 81  PRO n 
5 82  ASP n 
5 83  SER n 
5 84  PRO n 
5 85  GLU n 
5 86  MET n 
5 87  LYS n 
5 88  ASP n 
5 89  PHE n 
5 90  ARG n 
5 91  HIS n 
5 92  GLY n 
5 93  PHE n 
5 94  ASP n 
5 95  ILE n 
5 96  LEU n 
5 97  VAL n 
5 98  GLY n 
5 99  GLN n 
5 100 ILE n 
5 101 ASP n 
5 102 ASP n 
5 103 ALA n 
5 104 LEU n 
5 105 LYS n 
5 106 LEU n 
5 107 ALA n 
5 108 ASN n 
5 109 GLU n 
5 110 GLY n 
5 111 LYS n 
5 112 VAL n 
5 113 LYS n 
5 114 GLU n 
5 115 ALA n 
5 116 GLN n 
5 117 ALA n 
5 118 ALA n 
5 119 ALA n 
5 120 GLU n 
5 121 GLN n 
5 122 LEU n 
5 123 LYS n 
5 124 THR n 
5 125 THR n 
5 126 ARG n 
5 127 ASN n 
5 128 ALA n 
5 129 TYR n 
5 130 ILE n 
5 131 GLN n 
5 132 LYS n 
5 133 TYR n 
5 134 LEU n 
5 135 ALA n 
5 136 SER n 
5 137 GLU n 
5 138 ASN n 
5 139 LEU n 
5 140 TYR n 
5 141 PHE n 
5 142 GLN n 
5 143 GLY n 
5 144 GLY n 
5 145 GLY n 
5 146 GLY n 
5 147 GLY n 
5 148 SER n 
5 149 GLY n 
5 150 THR n 
5 151 MET n 
5 152 GLU n 
5 153 SER n 
5 154 SER n 
5 155 PHE n 
5 156 SER n 
5 157 PHE n 
5 158 GLY n 
5 159 VAL n 
5 160 ILE n 
5 161 LEU n 
5 162 ALA n 
5 163 VAL n 
5 164 LEU n 
5 165 ALA n 
5 166 SER n 
5 167 LEU n 
5 168 ILE n 
5 169 ILE n 
5 170 ALA n 
5 171 THR n 
5 172 ASN n 
5 173 THR n 
5 174 LEU n 
5 175 VAL n 
5 176 ALA n 
5 177 VAL n 
5 178 ALA n 
5 179 VAL n 
5 180 LEU n 
5 181 LEU n 
5 182 LEU n 
5 183 ILE n 
5 184 HIS n 
5 185 LYS n 
5 186 ASN n 
5 187 ASP n 
5 188 GLY n 
5 189 VAL n 
5 190 SER n 
5 191 LEU n 
5 192 CYS n 
5 193 PHE n 
5 194 THR n 
5 195 LEU n 
5 196 ASN n 
5 197 LEU n 
5 198 ALA n 
5 199 VAL n 
5 200 ALA n 
5 201 ASP n 
5 202 THR n 
5 203 LEU n 
5 204 ILE n 
5 205 GLY n 
5 206 VAL n 
5 207 ALA n 
5 208 ILE n 
5 209 SER n 
5 210 GLY n 
5 211 LEU n 
5 212 LEU n 
5 213 THR n 
5 214 ASP n 
5 215 GLN n 
5 216 LEU n 
5 217 SER n 
5 218 SER n 
5 219 PRO n 
5 220 SER n 
5 221 ARG n 
5 222 PRO n 
5 223 THR n 
5 224 GLN n 
5 225 LYS n 
5 226 THR n 
5 227 LEU n 
5 228 CYS n 
5 229 SER n 
5 230 LEU n 
5 231 ARG n 
5 232 MET n 
5 233 ALA n 
5 234 PHE n 
5 235 VAL n 
5 236 THR n 
5 237 SER n 
5 238 SER n 
5 239 ALA n 
5 240 ALA n 
5 241 ALA n 
5 242 SER n 
5 243 VAL n 
5 244 LEU n 
5 245 THR n 
5 246 VAL n 
5 247 MET n 
5 248 LEU n 
5 249 ILE n 
5 250 THR n 
5 251 PHE n 
5 252 ASP n 
5 253 ARG n 
5 254 TYR n 
5 255 LEU n 
5 256 ALA n 
5 257 ILE n 
5 258 LYS n 
5 259 GLN n 
5 260 PRO n 
5 261 PHE n 
5 262 ARG n 
5 263 TYR n 
5 264 LEU n 
5 265 LYS n 
5 266 ILE n 
5 267 MET n 
5 268 SER n 
5 269 GLY n 
5 270 PHE n 
5 271 VAL n 
5 272 ALA n 
5 273 GLY n 
5 274 ALA n 
5 275 CYS n 
5 276 ILE n 
5 277 ALA n 
5 278 GLY n 
5 279 LEU n 
5 280 TRP n 
5 281 LEU n 
5 282 VAL n 
5 283 SER n 
5 284 TYR n 
5 285 LEU n 
5 286 ILE n 
5 287 GLY n 
5 288 PHE n 
5 289 LEU n 
5 290 PRO n 
5 291 LEU n 
5 292 GLY n 
5 293 ILE n 
5 294 PRO n 
5 295 MET n 
5 296 PHE n 
5 297 GLN n 
5 298 GLN n 
5 299 THR n 
5 300 ALA n 
5 301 TYR n 
5 302 LYS n 
5 303 GLY n 
5 304 GLN n 
5 305 CYS n 
5 306 SER n 
5 307 PHE n 
5 308 PHE n 
5 309 ALA n 
5 310 VAL n 
5 311 PHE n 
5 312 HIS n 
5 313 PRO n 
5 314 HIS n 
5 315 PHE n 
5 316 VAL n 
5 317 LEU n 
5 318 THR n 
5 319 LEU n 
5 320 SER n 
5 321 CYS n 
5 322 VAL n 
5 323 GLY n 
5 324 PHE n 
5 325 PHE n 
5 326 PRO n 
5 327 ALA n 
5 328 MET n 
5 329 LEU n 
5 330 LEU n 
5 331 PHE n 
5 332 VAL n 
5 333 PHE n 
5 334 PHE n 
5 335 TYR n 
5 336 CYS n 
5 337 ASP n 
5 338 MET n 
5 339 LEU n 
5 340 LYS n 
5 341 ILE n 
5 342 ALA n 
5 343 SER n 
5 344 MET n 
5 345 HIS n 
5 346 SER n 
5 347 GLN n 
5 348 GLN n 
5 349 ILE n 
5 350 ARG n 
5 351 LYS n 
5 352 MET n 
5 353 GLU n 
5 354 HIS n 
5 355 ALA n 
5 356 GLY n 
5 357 ALA n 
5 358 MET n 
5 359 ALA n 
5 360 GLY n 
5 361 GLY n 
5 362 TYR n 
5 363 ARG n 
5 364 SER n 
5 365 PRO n 
5 366 ARG n 
5 367 THR n 
5 368 PRO n 
5 369 SER n 
5 370 ASP n 
5 371 PHE n 
5 372 LYS n 
5 373 ALA n 
5 374 LEU n 
5 375 ARG n 
5 376 THR n 
5 377 VAL n 
5 378 SER n 
5 379 VAL n 
5 380 LEU n 
5 381 ILE n 
5 382 GLY n 
5 383 SER n 
5 384 PHE n 
5 385 ALA n 
5 386 LEU n 
5 387 SER n 
5 388 TRP n 
5 389 THR n 
5 390 PRO n 
5 391 PHE n 
5 392 LEU n 
5 393 ILE n 
5 394 THR n 
5 395 GLY n 
5 396 ILE n 
5 397 VAL n 
5 398 GLN n 
5 399 VAL n 
5 400 ALA n 
5 401 CYS n 
5 402 GLN n 
5 403 GLU n 
5 404 CYS n 
5 405 HIS n 
5 406 LEU n 
5 407 TYR n 
5 408 LEU n 
5 409 VAL n 
5 410 LEU n 
5 411 GLU n 
5 412 ARG n 
5 413 TYR n 
5 414 LEU n 
5 415 TRP n 
5 416 LEU n 
5 417 LEU n 
5 418 GLY n 
5 419 VAL n 
5 420 GLY n 
5 421 ASN n 
5 422 SER n 
5 423 LEU n 
5 424 LEU n 
5 425 ASN n 
5 426 PRO n 
5 427 LEU n 
5 428 ILE n 
5 429 TYR n 
5 430 ALA n 
5 431 TYR n 
5 432 TRP n 
5 433 GLN n 
5 434 LYS n 
5 435 GLU n 
5 436 VAL n 
5 437 ARG n 
5 438 LEU n 
5 439 GLN n 
5 440 LEU n 
5 441 TYR n 
5 442 HIS n 
5 443 MET n 
5 444 ALA n 
5 445 LEU n 
5 446 GLY n 
5 447 VAL n 
5 448 LYS n 
5 449 LYS n 
5 450 VAL n 
5 451 LEU n 
5 452 THR n 
5 453 SER n 
5 454 PHE n 
5 455 LEU n 
5 456 LEU n 
5 457 PHE n 
5 458 LEU n 
5 459 SER n 
5 460 ALA n 
5 461 ARG n 
5 462 ASN n 
5 463 CYS n 
5 464 GLY n 
5 465 PRO n 
5 466 GLU n 
5 467 ARG n 
5 468 PRO n 
5 469 ARG n 
5 470 GLU n 
5 471 SER n 
5 472 SER n 
5 473 CYS n 
5 474 HIS n 
5 475 ILE n 
5 476 VAL n 
5 477 THR n 
5 478 ILE n 
5 479 SER n 
5 480 SER n 
5 481 SER n 
5 482 GLU n 
5 483 PHE n 
5 484 ASP n 
5 485 GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   394 ?     ? ?      ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 'Trichoplusia ni'  
7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   345 human ? GNB1   ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 'Trichoplusia ni'  
7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  human ? GNG2   ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 'Trichoplusia ni'  
7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   139 ?     ? ?      ? ? ? ? ? ? 'Lama glama'       9844 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   150 ?     ? cybC   ? ? ? ? ? ? 'Escherichia coli' 562  ? ? ? ? ? ? ? ? 'Trichoplusia ni'  
7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 151 485 human ? GPR119 ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? ? 'Trichoplusia ni'  
7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 7XZ5        7XZ5   ? 1 ? 1  
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2  
3 UNP GBG2_HUMAN  P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1  
4 PDB 7XZ5        7XZ5   ? 4 ? 1  
5 UNP C562_ECOLX  P0ABE7 ? 5 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23 
6 UNP GP119_HUMAN Q8TDV5 ? 5 
;MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSL
RMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAV
FHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRE
SSCHIVTISSSEFDG
;
1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 7XZ5 A 1   ? 394 ? 7XZ5   1  ? 394 ? 1    394 
2 2 7XZ5 B 7   ? 345 ? P62873 2  ? 340 ? 2    340 
3 3 7XZ5 G 1   ? 71  ? P59768 1  ? 71  ? 1    71  
4 4 7XZ5 N 1   ? 139 ? 7XZ5   0  ? 138 ? 0    138 
5 5 7XZ5 R 29  ? 133 ? P0ABE7 23 ? 127 ? -121 -17 
6 6 7XZ5 R 151 ? 485 ? Q8TDV5 1  ? 335 ? 1    335 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 7XZ5 MET B 1   ? UNP P62873 ?   ?   'initiating methionine' -4   1  
2 7XZ5 GLY B 2   ? UNP P62873 ?   ?   'expression tag'        -3   2  
2 7XZ5 SER B 3   ? UNP P62873 ?   ?   'expression tag'        -2   3  
2 7XZ5 LEU B 4   ? UNP P62873 ?   ?   'expression tag'        -1   4  
2 7XZ5 LEU B 5   ? UNP P62873 ?   ?   'expression tag'        0    5  
2 7XZ5 GLN B 6   ? UNP P62873 ?   ?   'expression tag'        1    6  
5 7XZ5 ASP R 1   ? UNP P0ABE7 ?   ?   'expression tag'        -149 7  
5 7XZ5 TYR R 2   ? UNP P0ABE7 ?   ?   'expression tag'        -148 8  
5 7XZ5 LYS R 3   ? UNP P0ABE7 ?   ?   'expression tag'        -147 9  
5 7XZ5 ASP R 4   ? UNP P0ABE7 ?   ?   'expression tag'        -146 10 
5 7XZ5 ASP R 5   ? UNP P0ABE7 ?   ?   'expression tag'        -145 11 
5 7XZ5 ASP R 6   ? UNP P0ABE7 ?   ?   'expression tag'        -144 12 
5 7XZ5 ASP R 7   ? UNP P0ABE7 ?   ?   'expression tag'        -143 13 
5 7XZ5 ALA R 8   ? UNP P0ABE7 ?   ?   'expression tag'        -142 14 
5 7XZ5 LYS R 9   ? UNP P0ABE7 ?   ?   'expression tag'        -141 15 
5 7XZ5 LEU R 10  ? UNP P0ABE7 ?   ?   'expression tag'        -140 16 
5 7XZ5 GLN R 11  ? UNP P0ABE7 ?   ?   'expression tag'        -139 17 
5 7XZ5 THR R 12  ? UNP P0ABE7 ?   ?   'expression tag'        -138 18 
5 7XZ5 MET R 13  ? UNP P0ABE7 ?   ?   'expression tag'        -137 19 
5 7XZ5 HIS R 14  ? UNP P0ABE7 ?   ?   'expression tag'        -136 20 
5 7XZ5 HIS R 15  ? UNP P0ABE7 ?   ?   'expression tag'        -135 21 
5 7XZ5 HIS R 16  ? UNP P0ABE7 ?   ?   'expression tag'        -134 22 
5 7XZ5 HIS R 17  ? UNP P0ABE7 ?   ?   'expression tag'        -133 23 
5 7XZ5 HIS R 18  ? UNP P0ABE7 ?   ?   'expression tag'        -132 24 
5 7XZ5 HIS R 19  ? UNP P0ABE7 ?   ?   'expression tag'        -131 25 
5 7XZ5 HIS R 20  ? UNP P0ABE7 ?   ?   'expression tag'        -130 26 
5 7XZ5 HIS R 21  ? UNP P0ABE7 ?   ?   'expression tag'        -129 27 
5 7XZ5 HIS R 22  ? UNP P0ABE7 ?   ?   'expression tag'        -128 28 
5 7XZ5 HIS R 23  ? UNP P0ABE7 ?   ?   'expression tag'        -127 29 
5 7XZ5 HIS R 24  ? UNP P0ABE7 ?   ?   'expression tag'        -126 30 
5 7XZ5 HIS R 25  ? UNP P0ABE7 ?   ?   'expression tag'        -125 31 
5 7XZ5 HIS R 26  ? UNP P0ABE7 ?   ?   'expression tag'        -124 32 
5 7XZ5 HIS R 27  ? UNP P0ABE7 ?   ?   'expression tag'        -123 33 
5 7XZ5 HIS R 28  ? UNP P0ABE7 ?   ?   'expression tag'        -122 34 
5 7XZ5 TRP R 35  ? UNP P0ABE7 MET 29  conflict                -115 35 
5 7XZ5 ILE R 130 ? UNP P0ABE7 HIS 124 conflict                -20  36 
5 7XZ5 LEU R 134 ? UNP P0ABE7 ?   ?   linker                  -16  37 
5 7XZ5 ALA R 135 ? UNP P0ABE7 ?   ?   linker                  -15  38 
5 7XZ5 SER R 136 ? UNP P0ABE7 ?   ?   linker                  -14  39 
5 7XZ5 GLU R 137 ? UNP P0ABE7 ?   ?   linker                  -13  40 
5 7XZ5 ASN R 138 ? UNP P0ABE7 ?   ?   linker                  -12  41 
5 7XZ5 LEU R 139 ? UNP P0ABE7 ?   ?   linker                  -11  42 
5 7XZ5 TYR R 140 ? UNP P0ABE7 ?   ?   linker                  -10  43 
5 7XZ5 PHE R 141 ? UNP P0ABE7 ?   ?   linker                  -9   44 
5 7XZ5 GLN R 142 ? UNP P0ABE7 ?   ?   linker                  -8   45 
5 7XZ5 GLY R 143 ? UNP P0ABE7 ?   ?   linker                  -7   46 
5 7XZ5 GLY R 144 ? UNP P0ABE7 ?   ?   linker                  -6   47 
5 7XZ5 GLY R 145 ? UNP P0ABE7 ?   ?   linker                  -5   48 
5 7XZ5 GLY R 146 ? UNP P0ABE7 ?   ?   linker                  -4   49 
5 7XZ5 GLY R 147 ? UNP P0ABE7 ?   ?   linker                  -3   50 
5 7XZ5 SER R 148 ? UNP P0ABE7 ?   ?   linker                  -2   51 
5 7XZ5 GLY R 149 ? UNP P0ABE7 ?   ?   linker                  -1   52 
5 7XZ5 THR R 150 ? UNP P0ABE7 ?   ?   linker                  0    53 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE ? 'C2 H5 N O2'       75.067  
HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'   156.162 
ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'      131.173 
LSC non-polymer         . 
'(4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide' ? 'C26 H53 N O7 P 1' 
522.675 
LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2'      117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   7XZ5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 7XZ5 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002  ? 8429  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.406  ? 11403 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 41.136 ? 1162  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.037  ? 1289  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.002  ? 1450  ? f_plane_restr      ? ? 
# 
_struct.entry_id                                   7XZ5 
_struct.title                                      'GPR119-Gs-LPC complex' 
_struct.pdbx_structure_determination_methodology   ? 
_struct.pdbx_model_details                         ? 
_struct.pdbx_formula_weight                        ? 
_struct.pdbx_formula_weight_method                 ? 
_struct.pdbx_model_type_details                    ? 
_struct.pdbx_CASP_flag                             N 
# 
_struct_keywords.entry_id        7XZ5 
_struct_keywords.text            
;GPCR, Glucose-dependent insulinotropic receptor, GPR119, LysoPC, Lysophosphatidylcholine, G-protein, Gs, signaling complex, structure-function relationships, MEMBRANE PROTEIN
;
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 9   ? ALA A 39  ? THR A 9   ALA A 39  1 ? 31 
HELX_P HELX_P2  AA2 GLY A 52  ? ILE A 62  ? GLY A 52  ILE A 62  1 ? 11 
HELX_P HELX_P3  AA3 LYS A 233 ? ASN A 239 ? LYS A 233 ASN A 239 5 ? 7  
HELX_P HELX_P4  AA4 ASN A 264 ? ASN A 279 ? ASN A 264 ASN A 279 1 ? 16 
HELX_P HELX_P5  AA5 LYS A 293 ? ALA A 303 ? LYS A 293 ALA A 303 1 ? 11 
HELX_P HELX_P6  AA6 PHE A 312 ? TYR A 318 ? PHE A 312 TYR A 318 5 ? 7  
HELX_P HELX_P7  AA7 ASP A 331 ? ALA A 351 ? ASP A 331 ALA A 351 1 ? 21 
HELX_P HELX_P8  AA8 THR A 369 ? TYR A 391 ? THR A 369 TYR A 391 1 ? 23 
HELX_P HELX_P9  AA9 LEU B 9   ? CYS B 30  ? LEU B 4   CYS B 25  1 ? 22 
HELX_P HELX_P10 AB1 THR B 34  ? THR B 39  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P11 AB2 ALA C 7   ? ASN C 24  ? ALA G 7   ASN G 24  1 ? 18 
HELX_P HELX_P12 AB3 LYS C 29  ? HIS C 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P13 AB4 THR D 29  ? TYR D 33  ? THR N 28  TYR N 32  5 ? 5  
HELX_P HELX_P14 AB5 LYS D 88  ? THR D 92  ? LYS N 87  THR N 91  5 ? 5  
HELX_P HELX_P15 AB6 GLU E 152 ? ASN E 186 ? GLU R 2   ASN R 36  1 ? 35 
HELX_P HELX_P16 AB7 VAL E 189 ? LEU E 211 ? VAL R 39  LEU R 61  1 ? 23 
HELX_P HELX_P17 AB8 LEU E 211 ? LEU E 216 ? LEU R 61  LEU R 66  1 ? 6  
HELX_P HELX_P18 AB9 THR E 223 ? GLN E 259 ? THR R 73  GLN R 109 1 ? 37 
HELX_P HELX_P19 AC1 GLN E 259 ? MET E 267 ? GLN R 109 MET R 117 1 ? 9  
HELX_P HELX_P20 AC2 SER E 268 ? ILE E 293 ? SER R 118 ILE R 143 1 ? 26 
HELX_P HELX_P21 AC3 HIS E 312 ? VAL E 322 ? HIS R 162 VAL R 172 1 ? 11 
HELX_P HELX_P22 AC4 GLY E 323 ? GLY E 360 ? GLY R 173 GLY R 210 1 ? 38 
HELX_P HELX_P23 AC5 PHE E 371 ? CYS E 401 ? PHE R 221 CYS R 251 1 ? 31 
HELX_P HELX_P24 AC6 LEU E 406 ? GLU E 411 ? LEU R 256 GLU R 261 1 ? 6  
HELX_P HELX_P25 AC7 TYR E 413 ? TYR E 429 ? TYR R 263 TYR R 279 1 ? 17 
HELX_P HELX_P26 AC8 GLN E 433 ? LYS E 449 ? GLN R 283 LYS R 299 1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 23  SG ? ? ? 1_555 D CYS 97  SG ? ? N CYS 22  N CYS 96  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2 disulf ? ? D CYS 100 SG ? ? ? 1_555 D CYS 108 SG ? ? N CYS 99  N CYS 107 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf3 disulf ? ? E CYS 228 SG ? ? ? 1_555 E CYS 305 SG ? ? R CYS 78  R CYS 155 1_555 ? ? ? ? ? ? ? 2.045 ? ? 
disulf4 disulf ? ? E CYS 401 SG ? ? ? 1_555 E CYS 404 SG ? ? R CYS 251 R CYS 254 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 208 ? VAL A 214 ? PHE A 208 VAL A 214 
AA1 2 VAL A 217 ? ASP A 223 ? VAL A 217 ASP A 223 
AA1 3 THR A 40  ? LEU A 46  ? THR A 40  LEU A 46  
AA1 4 ALA A 243 ? ALA A 249 ? ALA A 243 ALA A 249 
AA1 5 SER A 286 ? ASN A 292 ? SER A 286 ASN A 292 
AA1 6 CYS A 359 ? PHE A 363 ? CYS A 359 PHE A 363 
AA2 1 ARG B 51  ? LEU B 56  ? ARG B 46  LEU B 51  
AA2 2 LEU B 341 ? ASN B 345 ? LEU B 336 ASN B 340 
AA2 3 VAL B 332 ? SER B 336 ? VAL B 327 SER B 331 
AA2 4 VAL B 320 ? VAL B 325 ? VAL B 315 VAL B 320 
AA3 1 ILE B 63  ? TRP B 68  ? ILE B 58  TRP B 63  
AA3 2 LEU B 74  ? SER B 79  ? LEU B 69  SER B 74  
AA3 3 LYS B 83  ? ASP B 88  ? LYS B 78  ASP B 83  
AA3 4 LYS B 94  ? PRO B 99  ? LYS B 89  PRO B 94  
AA4 1 VAL B 105 ? TYR B 110 ? VAL B 100 TYR B 105 
AA4 2 TYR B 116 ? GLY B 121 ? TYR B 111 GLY B 116 
AA4 3 CYS B 126 ? ASN B 130 ? CYS B 121 ASN B 125 
AA4 4 ARG B 139 ? LEU B 144 ? ARG B 134 LEU B 139 
AA5 1 LEU B 151 ? PHE B 156 ? LEU B 146 PHE B 151 
AA5 2 GLN B 161 ? SER B 166 ? GLN B 156 SER B 161 
AA5 3 CYS B 171 ? ASP B 175 ? CYS B 166 ASP B 170 
AA5 4 GLN B 180 ? PHE B 185 ? GLN B 175 PHE B 180 
AA6 1 SER B 194 ? LEU B 197 ? SER B 189 LEU B 192 
AA6 2 LEU B 203 ? GLY B 207 ? LEU B 198 GLY B 202 
AA6 3 ALA B 213 ? ASP B 217 ? ALA B 208 ASP B 212 
AA6 4 CYS B 223 ? PHE B 227 ? CYS B 218 PHE B 222 
AA7 1 ILE B 234 ? PHE B 239 ? ILE B 229 PHE B 234 
AA7 2 ALA B 245 ? SER B 250 ? ALA B 240 SER B 245 
AA7 3 CYS B 255 ? ASP B 259 ? CYS B 250 ASP B 254 
AA7 4 GLU B 265 ? TYR B 269 ? GLU B 260 TYR B 264 
AA8 1 ILE B 278 ? PHE B 283 ? ILE B 273 PHE B 278 
AA8 2 LEU B 289 ? TYR B 294 ? LEU B 284 TYR B 289 
AA8 3 CYS B 299 ? ASP B 303 ? CYS B 294 ASP B 298 
AA8 4 ARG B 309 ? LEU B 313 ? ARG B 304 LEU B 308 
AA9 1 GLN D 4   ? SER D 8   ? GLN N 3   SER N 7   
AA9 2 SER D 18  ? SER D 26  ? SER N 17  SER N 25  
AA9 3 THR D 79  ? ASN D 85  ? THR N 78  ASN N 84  
AA9 4 THR D 70  ? ASP D 74  ? THR N 69  ASP N 73  
AB1 1 GLY D 11  ? VAL D 13  ? GLY N 10  VAL N 12  
AB1 2 THR D 123 ? VAL D 127 ? THR N 122 VAL N 126 
AB1 3 ALA D 93  ? ARG D 99  ? ALA N 92  ARG N 98  
AB1 4 MET D 35  ? GLN D 40  ? MET N 34  GLN N 39  
AB1 5 LEU D 46  ? ILE D 52  ? LEU N 45  ILE N 51  
AB1 6 ILE D 59  ? TYR D 61  ? ILE N 58  TYR N 60  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 208 ? N PHE A 208 O ASP A 223 ? O ASP A 223 
AA1 2 3 O HIS A 220 ? O HIS A 220 N LEU A 43  ? N LEU A 43  
AA1 3 4 N LEU A 44  ? N LEU A 44  O ILE A 245 ? O ILE A 245 
AA1 4 5 N PHE A 246 ? N PHE A 246 O PHE A 290 ? O PHE A 290 
AA1 5 6 N LEU A 291 ? N LEU A 291 O HIS A 362 ? O HIS A 362 
AA2 1 2 N ARG B 53  ? N ARG B 48  O ILE B 343 ? O ILE B 338 
AA2 2 3 O TRP B 344 ? O TRP B 339 N VAL B 332 ? N VAL B 327 
AA2 3 4 O ALA B 333 ? O ALA B 328 N GLY B 324 ? N GLY B 319 
AA3 1 2 N ALA B 65  ? N ALA B 60  O ALA B 78  ? O ALA B 73  
AA3 2 3 N LEU B 75  ? N LEU B 70  O TRP B 87  ? O TRP B 82  
AA3 3 4 N LEU B 84  ? N LEU B 79  O ILE B 98  ? O ILE B 93  
AA4 1 2 N MET B 106 ? N MET B 101 O GLY B 120 ? O GLY B 115 
AA4 2 3 N VAL B 117 ? N VAL B 112 O TYR B 129 ? O TYR B 124 
AA4 3 4 N ILE B 128 ? N ILE B 123 O SER B 141 ? O SER B 136 
AA5 1 2 N CYS B 153 ? N CYS B 148 O SER B 165 ? O SER B 160 
AA5 2 3 N ILE B 162 ? N ILE B 157 O TRP B 174 ? O TRP B 169 
AA5 3 4 N CYS B 171 ? N CYS B 166 O PHE B 185 ? O PHE B 180 
AA6 1 2 N SER B 196 ? N SER B 191 O VAL B 205 ? O VAL B 200 
AA6 2 3 N PHE B 204 ? N PHE B 199 O TRP B 216 ? O TRP B 211 
AA6 3 4 N ALA B 213 ? N ALA B 208 O PHE B 227 ? O PHE B 222 
AA7 1 2 N ASN B 235 ? N ASN B 230 O GLY B 249 ? O GLY B 244 
AA7 2 3 N PHE B 246 ? N PHE B 241 O PHE B 258 ? O PHE B 253 
AA7 3 4 N CYS B 255 ? N CYS B 250 O TYR B 269 ? O TYR B 264 
AA8 1 2 N SER B 282 ? N SER B 277 O LEU B 291 ? O LEU B 286 
AA8 2 3 N LEU B 290 ? N LEU B 285 O TRP B 302 ? O TRP B 297 
AA8 3 4 N CYS B 299 ? N CYS B 294 O LEU B 313 ? O LEU B 308 
AA9 1 2 N GLN D 6   ? N GLN N 5   O ALA D 24  ? O ALA N 23  
AA9 2 3 N LEU D 19  ? N LEU N 18  O MET D 84  ? O MET N 83  
AA9 3 4 O TYR D 81  ? O TYR N 80  N SER D 72  ? N SER N 71  
AB1 1 2 N GLY D 11  ? N GLY N 10  O GLN D 124 ? O GLN N 123 
AB1 2 3 O THR D 123 ? O THR N 122 N TYR D 95  ? N TYR N 94  
AB1 3 4 O TYR D 96  ? O TYR N 95  N VAL D 38  ? N VAL N 37  
AB1 4 5 N TRP D 37  ? N TRP N 36  O VAL D 49  ? O VAL N 48  
AB1 5 6 N ASP D 51  ? N ASP N 50  O SER D 60  ? O SER N 59  
# 
_atom_sites.entry_id                    7XZ5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N    . THR A 1 9   ? 84.199  73.478  120.388 1.00 73.93  ?  9   THR A N    1 
ATOM   2     C CA   . THR A 1 9   ? 84.707  74.136  121.625 1.00 73.93  ?  9   THR A CA   1 
ATOM   3     C C    . THR A 1 9   ? 84.121  75.537  121.770 1.00 73.93  ?  9   THR A C    1 
ATOM   4     O O    . THR A 1 9   ? 84.798  76.534  121.522 1.00 73.93  ?  9   THR A O    1 
ATOM   5     C CB   . THR A 1 9   ? 86.245  74.228  121.623 1.00 73.93  ?  9   THR A CB   1 
ATOM   6     O OG1  . THR A 1 9   ? 86.695  74.756  120.369 1.00 73.93  ?  9   THR A OG1  1 
ATOM   7     C CG2  . THR A 1 9   ? 86.862  72.855  121.844 1.00 73.93  ?  9   THR A CG2  1 
ATOM   8     H H    . THR A 1 9   ? 83.309  73.463  120.404 1.00 73.93  ?  9   THR A H    1 
ATOM   9     H HA   . THR A 1 9   ? 84.437  73.614  122.396 1.00 73.93  ?  9   THR A HA   1 
ATOM   10    H HB   . THR A 1 9   ? 86.533  74.813  122.341 1.00 73.93  ?  9   THR A HB   1 
ATOM   11    H HG1  . THR A 1 9   ? 87.533  74.799  120.360 1.00 73.93  ?  9   THR A HG1  1 
ATOM   12    H HG21 . THR A 1 9   ? 87.830  72.924  121.853 1.00 73.93  ?  9   THR A HG21 1 
ATOM   13    H HG22 . THR A 1 9   ? 86.564  72.490  122.692 1.00 73.93  ?  9   THR A HG22 1 
ATOM   14    H HG23 . THR A 1 9   ? 86.596  72.253  121.131 1.00 73.93  ?  9   THR A HG23 1 
ATOM   15    N N    . GLU A 1 10  ? 82.850  75.603  122.176 1.00 74.15  ?  10  GLU A N    1 
ATOM   16    C CA   . GLU A 1 10  ? 82.189  76.894  122.332 1.00 74.15  ?  10  GLU A CA   1 
ATOM   17    C C    . GLU A 1 10  ? 82.798  77.706  123.468 1.00 74.15  ?  10  GLU A C    1 
ATOM   18    O O    . GLU A 1 10  ? 82.870  78.937  123.378 1.00 74.15  ?  10  GLU A O    1 
ATOM   19    C CB   . GLU A 1 10  ? 80.693  76.689  122.570 1.00 74.15  ?  10  GLU A CB   1 
ATOM   20    C CG   . GLU A 1 10  ? 79.967  76.050  121.397 1.00 74.15  ?  10  GLU A CG   1 
ATOM   21    C CD   . GLU A 1 10  ? 78.465  75.999  121.597 1.00 74.15  ?  10  GLU A CD   1 
ATOM   22    O OE1  . GLU A 1 10  ? 78.022  75.828  122.753 1.00 74.15  ?  10  GLU A OE1  1 
ATOM   23    O OE2  . GLU A 1 10  ? 77.726  76.131  120.599 1.00 74.15  -1 10  GLU A OE2  1 
ATOM   24    H H    . GLU A 1 10  ? 82.358  74.923  122.363 1.00 74.15  ?  10  GLU A H    1 
ATOM   25    H HA   . GLU A 1 10  ? 82.294  77.402  121.513 1.00 74.15  ?  10  GLU A HA   1 
ATOM   26    H HB2  . GLU A 1 10  ? 80.576  76.112  123.342 1.00 74.15  ?  10  GLU A HB2  1 
ATOM   27    H HB3  . GLU A 1 10  ? 80.283  77.551  122.739 1.00 74.15  ?  10  GLU A HB3  1 
ATOM   28    H HG2  . GLU A 1 10  ? 80.146  76.565  120.596 1.00 74.15  ?  10  GLU A HG2  1 
ATOM   29    H HG3  . GLU A 1 10  ? 80.285  75.140  121.285 1.00 74.15  ?  10  GLU A HG3  1 
ATOM   30    N N    . ASP A 1 11  ? 83.233  77.043  124.543 1.00 71.20  ?  11  ASP A N    1 
ATOM   31    C CA   . ASP A 1 11  ? 83.840  77.764  125.657 1.00 71.20  ?  11  ASP A CA   1 
ATOM   32    C C    . ASP A 1 11  ? 85.119  78.469  125.225 1.00 71.20  ?  11  ASP A C    1 
ATOM   33    O O    . ASP A 1 11  ? 85.401  79.590  125.666 1.00 71.20  ?  11  ASP A O    1 
ATOM   34    C CB   . ASP A 1 11  ? 84.123  76.801  126.810 1.00 71.20  ?  11  ASP A CB   1 
ATOM   35    C CG   . ASP A 1 11  ? 82.861  76.169  127.364 1.00 71.20  ?  11  ASP A CG   1 
ATOM   36    O OD1  . ASP A 1 11  ? 81.761  76.689  127.083 1.00 71.20  ?  11  ASP A OD1  1 
ATOM   37    O OD2  . ASP A 1 11  ? 82.969  75.151  128.080 1.00 71.20  -1 11  ASP A OD2  1 
ATOM   38    H H    . ASP A 1 11  ? 83.190  76.191  124.647 1.00 71.20  ?  11  ASP A H    1 
ATOM   39    H HA   . ASP A 1 11  ? 83.218  78.438  125.974 1.00 71.20  ?  11  ASP A HA   1 
ATOM   40    H HB2  . ASP A 1 11  ? 84.701  76.089  126.494 1.00 71.20  ?  11  ASP A HB2  1 
ATOM   41    H HB3  . ASP A 1 11  ? 84.556  77.286  127.530 1.00 71.20  ?  11  ASP A HB3  1 
ATOM   42    N N    . GLN A 1 12  ? 85.916  77.820  124.373 1.00 68.61  ?  12  GLN A N    1 
ATOM   43    C CA   . GLN A 1 12  ? 87.139  78.445  123.881 1.00 68.61  ?  12  GLN A CA   1 
ATOM   44    C C    . GLN A 1 12  ? 86.823  79.713  123.097 1.00 68.61  ?  12  GLN A C    1 
ATOM   45    O O    . GLN A 1 12  ? 87.480  80.745  123.270 1.00 68.61  ?  12  GLN A O    1 
ATOM   46    C CB   . GLN A 1 12  ? 87.919  77.453  123.017 1.00 68.61  ?  12  GLN A CB   1 
ATOM   47    C CG   . GLN A 1 12  ? 89.264  77.973  122.533 1.00 68.61  ?  12  GLN A CG   1 
ATOM   48    C CD   . GLN A 1 12  ? 90.033  76.942  121.731 1.00 68.61  ?  12  GLN A CD   1 
ATOM   49    O OE1  . GLN A 1 12  ? 89.549  75.834  121.497 1.00 68.61  ?  12  GLN A OE1  1 
ATOM   50    N NE2  . GLN A 1 12  ? 91.239  77.300  121.307 1.00 68.61  ?  12  GLN A NE2  1 
ATOM   51    H H    . GLN A 1 12  ? 85.771  77.028  124.069 1.00 68.61  ?  12  GLN A H    1 
ATOM   52    H HA   . GLN A 1 12  ? 87.697  78.686  124.637 1.00 68.61  ?  12  GLN A HA   1 
ATOM   53    H HB2  . GLN A 1 12  ? 88.083  76.650  123.537 1.00 68.61  ?  12  GLN A HB2  1 
ATOM   54    H HB3  . GLN A 1 12  ? 87.388  77.235  122.236 1.00 68.61  ?  12  GLN A HB3  1 
ATOM   55    H HG2  . GLN A 1 12  ? 89.121  78.747  121.966 1.00 68.61  ?  12  GLN A HG2  1 
ATOM   56    H HG3  . GLN A 1 12  ? 89.803  78.219  123.301 1.00 68.61  ?  12  GLN A HG3  1 
ATOM   57    H HE21 . GLN A 1 12  ? 91.544  78.083  121.490 1.00 68.61  ?  12  GLN A HE21 1 
ATOM   58    H HE22 . GLN A 1 12  ? 91.715  76.750  120.848 1.00 68.61  ?  12  GLN A HE22 1 
ATOM   59    N N    . ARG A 1 13  ? 85.810  79.655  122.231 1.00 67.95  ?  13  ARG A N    1 
ATOM   60    C CA   . ARG A 1 13  ? 85.426  80.841  121.471 1.00 67.95  ?  13  ARG A CA   1 
ATOM   61    C C    . ARG A 1 13  ? 84.891  81.934  122.389 1.00 67.95  ?  13  ARG A C    1 
ATOM   62    O O    . ARG A 1 13  ? 85.169  83.120  122.181 1.00 67.95  ?  13  ARG A O    1 
ATOM   63    C CB   . ARG A 1 13  ? 84.393  80.469  120.409 1.00 67.95  ?  13  ARG A CB   1 
ATOM   64    C CG   . ARG A 1 13  ? 84.923  79.507  119.356 1.00 67.95  ?  13  ARG A CG   1 
ATOM   65    C CD   . ARG A 1 13  ? 83.843  79.094  118.371 1.00 67.95  ?  13  ARG A CD   1 
ATOM   66    N NE   . ARG A 1 13  ? 84.356  78.180  117.354 1.00 67.95  ?  13  ARG A NE   1 
ATOM   67    C CZ   . ARG A 1 13  ? 83.618  77.632  116.394 1.00 67.95  ?  13  ARG A CZ   1 
ATOM   68    N NH1  . ARG A 1 13  ? 84.177  76.812  115.515 1.00 67.95  1  13  ARG A NH1  1 
ATOM   69    N NH2  . ARG A 1 13  ? 82.322  77.903  116.308 1.00 67.95  ?  13  ARG A NH2  1 
ATOM   70    H H    . ARG A 1 13  ? 85.338  78.955  122.068 1.00 67.95  ?  13  ARG A H    1 
ATOM   71    H HA   . ARG A 1 13  ? 86.209  81.189  121.017 1.00 67.95  ?  13  ARG A HA   1 
ATOM   72    H HB2  . ARG A 1 13  ? 83.635  80.046  120.843 1.00 67.95  ?  13  ARG A HB2  1 
ATOM   73    H HB3  . ARG A 1 13  ? 84.104  81.276  119.956 1.00 67.95  ?  13  ARG A HB3  1 
ATOM   74    H HG2  . ARG A 1 13  ? 85.636  79.938  118.861 1.00 67.95  ?  13  ARG A HG2  1 
ATOM   75    H HG3  . ARG A 1 13  ? 85.255  78.707  119.793 1.00 67.95  ?  13  ARG A HG3  1 
ATOM   76    H HD2  . ARG A 1 13  ? 83.129  78.645  118.850 1.00 67.95  ?  13  ARG A HD2  1 
ATOM   77    H HD3  . ARG A 1 13  ? 83.501  79.884  117.923 1.00 67.95  ?  13  ARG A HD3  1 
ATOM   78    H HE   . ARG A 1 13  ? 85.192  77.977  117.383 1.00 67.95  ?  13  ARG A HE   1 
ATOM   79    H HH11 . ARG A 1 13  ? 85.017  76.634  115.567 1.00 67.95  ?  13  ARG A HH11 1 
ATOM   80    H HH12 . ARG A 1 13  ? 83.700  76.458  114.893 1.00 67.95  ?  13  ARG A HH12 1 
ATOM   81    H HH21 . ARG A 1 13  ? 81.952  78.434  116.874 1.00 67.95  ?  13  ARG A HH21 1 
ATOM   82    H HH22 . ARG A 1 13  ? 81.850  77.545  115.684 1.00 67.95  ?  13  ARG A HH22 1 
ATOM   83    N N    . ASN A 1 14  ? 84.119  81.555  123.410 1.00 63.94  ?  14  ASN A N    1 
ATOM   84    C CA   . ASN A 1 14  ? 83.590  82.550  124.339 1.00 63.94  ?  14  ASN A CA   1 
ATOM   85    C C    . ASN A 1 14  ? 84.711  83.254  125.094 1.00 63.94  ?  14  ASN A C    1 
ATOM   86    O O    . ASN A 1 14  ? 84.710  84.486  125.216 1.00 63.94  ?  14  ASN A O    1 
ATOM   87    C CB   . ASN A 1 14  ? 82.621  81.886  125.317 1.00 63.94  ?  14  ASN A CB   1 
ATOM   88    C CG   . ASN A 1 14  ? 81.478  82.799  125.719 1.00 63.94  ?  14  ASN A CG   1 
ATOM   89    O OD1  . ASN A 1 14  ? 80.974  83.577  124.909 1.00 63.94  ?  14  ASN A OD1  1 
ATOM   90    N ND2  . ASN A 1 14  ? 81.063  82.707  126.978 1.00 63.94  ?  14  ASN A ND2  1 
ATOM   91    H H    . ASN A 1 14  ? 83.893  80.744  123.583 1.00 63.94  ?  14  ASN A H    1 
ATOM   92    H HA   . ASN A 1 14  ? 83.101  83.220  123.836 1.00 63.94  ?  14  ASN A HA   1 
ATOM   93    H HB2  . ASN A 1 14  ? 82.241  81.097  124.900 1.00 63.94  ?  14  ASN A HB2  1 
ATOM   94    H HB3  . ASN A 1 14  ? 83.103  81.637  126.121 1.00 63.94  ?  14  ASN A HB3  1 
ATOM   95    H HD21 . ASN A 1 14  ? 81.440  82.152  127.515 1.00 63.94  ?  14  ASN A HD21 1 
ATOM   96    H HD22 . ASN A 1 14  ? 80.418  83.204  127.255 1.00 63.94  ?  14  ASN A HD22 1 
ATOM   97    N N    . GLU A 1 15  ? 85.679  82.491  125.609 1.00 61.37  ?  15  GLU A N    1 
ATOM   98    C CA   . GLU A 1 15  ? 86.787  83.116  126.323 1.00 61.37  ?  15  GLU A CA   1 
ATOM   99    C C    . GLU A 1 15  ? 87.666  83.929  125.381 1.00 61.37  ?  15  GLU A C    1 
ATOM   100   O O    . GLU A 1 15  ? 88.209  84.961  125.786 1.00 61.37  ?  15  GLU A O    1 
ATOM   101   C CB   . GLU A 1 15  ? 87.616  82.065  127.067 1.00 61.37  ?  15  GLU A CB   1 
ATOM   102   C CG   . GLU A 1 15  ? 88.185  80.951  126.204 1.00 61.37  ?  15  GLU A CG   1 
ATOM   103   C CD   . GLU A 1 15  ? 89.486  81.333  125.520 1.00 61.37  ?  15  GLU A CD   1 
ATOM   104   O OE1  . GLU A 1 15  ? 90.147  82.289  125.978 1.00 61.37  ?  15  GLU A OE1  1 
ATOM   105   O OE2  . GLU A 1 15  ? 89.849  80.674  124.523 1.00 61.37  -1 15  GLU A OE2  1 
ATOM   106   H H    . GLU A 1 15  ? 85.712  81.633  125.561 1.00 61.37  ?  15  GLU A H    1 
ATOM   107   H HA   . GLU A 1 15  ? 86.424  83.726  126.985 1.00 61.37  ?  15  GLU A HA   1 
ATOM   108   H HB2  . GLU A 1 15  ? 88.357  82.509  127.507 1.00 61.37  ?  15  GLU A HB2  1 
ATOM   109   H HB3  . GLU A 1 15  ? 87.049  81.649  127.735 1.00 61.37  ?  15  GLU A HB3  1 
ATOM   110   H HG2  . GLU A 1 15  ? 88.362  80.181  126.766 1.00 61.37  ?  15  GLU A HG2  1 
ATOM   111   H HG3  . GLU A 1 15  ? 87.538  80.719  125.526 1.00 61.37  ?  15  GLU A HG3  1 
ATOM   112   N N    . GLU A 1 16  ? 87.810  83.497  124.125 1.00 55.42  ?  16  GLU A N    1 
ATOM   113   C CA   . GLU A 1 16  ? 88.541  84.304  123.154 1.00 55.42  ?  16  GLU A CA   1 
ATOM   114   C C    . GLU A 1 16  ? 87.838  85.634  122.906 1.00 55.42  ?  16  GLU A C    1 
ATOM   115   O O    . GLU A 1 16  ? 88.488  86.679  122.802 1.00 55.42  ?  16  GLU A O    1 
ATOM   116   C CB   . GLU A 1 16  ? 88.702  83.530  121.846 1.00 55.42  ?  16  GLU A CB   1 
ATOM   117   C CG   . GLU A 1 16  ? 89.765  84.098  120.917 1.00 55.42  ?  16  GLU A CG   1 
ATOM   118   C CD   . GLU A 1 16  ? 91.151  83.556  121.211 1.00 55.42  ?  16  GLU A CD   1 
ATOM   119   O OE1  . GLU A 1 16  ? 91.274  82.344  121.486 1.00 55.42  ?  16  GLU A OE1  1 
ATOM   120   O OE2  . GLU A 1 16  ? 92.120  84.344  121.166 1.00 55.42  -1 16  GLU A OE2  1 
ATOM   121   H H    . GLU A 1 16  ? 87.500  82.756  123.818 1.00 55.42  ?  16  GLU A H    1 
ATOM   122   H HA   . GLU A 1 16  ? 89.426  84.493  123.502 1.00 55.42  ?  16  GLU A HA   1 
ATOM   123   H HB2  . GLU A 1 16  ? 88.947  82.615  122.054 1.00 55.42  ?  16  GLU A HB2  1 
ATOM   124   H HB3  . GLU A 1 16  ? 87.857  83.542  121.370 1.00 55.42  ?  16  GLU A HB3  1 
ATOM   125   H HG2  . GLU A 1 16  ? 89.541  83.868  120.001 1.00 55.42  ?  16  GLU A HG2  1 
ATOM   126   H HG3  . GLU A 1 16  ? 89.793  85.062  121.019 1.00 55.42  ?  16  GLU A HG3  1 
ATOM   127   N N    . LYS A 1 17  ? 86.508  85.611  122.796 1.00 55.30  ?  17  LYS A N    1 
ATOM   128   C CA   . LYS A 1 17  ? 85.759  86.852  122.618 1.00 55.30  ?  17  LYS A CA   1 
ATOM   129   C C    . LYS A 1 17  ? 85.908  87.762  123.832 1.00 55.30  ?  17  LYS A C    1 
ATOM   130   O O    . LYS A 1 17  ? 86.059  88.983  123.692 1.00 55.30  ?  17  LYS A O    1 
ATOM   131   C CB   . LYS A 1 17  ? 84.285  86.537  122.362 1.00 55.30  ?  17  LYS A CB   1 
ATOM   132   C CG   . LYS A 1 17  ? 83.429  87.760  122.062 1.00 55.30  ?  17  LYS A CG   1 
ATOM   133   C CD   . LYS A 1 17  ? 82.016  87.408  121.583 1.00 55.30  ?  17  LYS A CD   1 
ATOM   134   C CE   . LYS A 1 17  ? 81.448  86.141  122.223 1.00 55.30  ?  17  LYS A CE   1 
ATOM   135   N NZ   . LYS A 1 17  ? 80.129  85.776  121.637 1.00 55.30  1  17  LYS A NZ   1 
ATOM   136   H H    . LYS A 1 17  ? 86.024  84.901  122.822 1.00 55.30  ?  17  LYS A H    1 
ATOM   137   H HA   . LYS A 1 17  ? 86.105  87.323  121.844 1.00 55.30  ?  17  LYS A HA   1 
ATOM   138   H HB2  . LYS A 1 17  ? 84.223  85.937  121.603 1.00 55.30  ?  17  LYS A HB2  1 
ATOM   139   H HB3  . LYS A 1 17  ? 83.925  86.106  123.153 1.00 55.30  ?  17  LYS A HB3  1 
ATOM   140   H HG2  . LYS A 1 17  ? 83.347  88.293  122.869 1.00 55.30  ?  17  LYS A HG2  1 
ATOM   141   H HG3  . LYS A 1 17  ? 83.859  88.281  121.366 1.00 55.30  ?  17  LYS A HG3  1 
ATOM   142   H HD2  . LYS A 1 17  ? 81.420  88.142  121.797 1.00 55.30  ?  17  LYS A HD2  1 
ATOM   143   H HD3  . LYS A 1 17  ? 82.037  87.271  120.622 1.00 55.30  ?  17  LYS A HD3  1 
ATOM   144   H HE2  . LYS A 1 17  ? 82.043  85.393  122.067 1.00 55.30  ?  17  LYS A HE2  1 
ATOM   145   H HE3  . LYS A 1 17  ? 81.330  86.286  123.174 1.00 55.30  ?  17  LYS A HE3  1 
ATOM   146   H HZ1  . LYS A 1 17  ? 79.817  85.038  122.025 1.00 55.30  ?  17  LYS A HZ1  1 
ATOM   147   H HZ2  . LYS A 1 17  ? 79.547  86.437  121.763 1.00 55.30  ?  17  LYS A HZ2  1 
ATOM   148   H HZ3  . LYS A 1 17  ? 80.215  85.629  120.763 1.00 55.30  ?  17  LYS A HZ3  1 
ATOM   149   N N    . ALA A 1 18  ? 85.856  87.186  125.035 1.00 49.02  ?  18  ALA A N    1 
ATOM   150   C CA   . ALA A 1 18  ? 86.063  87.984  126.240 1.00 49.02  ?  18  ALA A CA   1 
ATOM   151   C C    . ALA A 1 18  ? 87.458  88.597  126.255 1.00 49.02  ?  18  ALA A C    1 
ATOM   152   O O    . ALA A 1 18  ? 87.634  89.763  126.635 1.00 49.02  ?  18  ALA A O    1 
ATOM   153   C CB   . ALA A 1 18  ? 85.841  87.122  127.482 1.00 49.02  ?  18  ALA A CB   1 
ATOM   154   H H    . ALA A 1 18  ? 85.707  86.351  125.176 1.00 49.02  ?  18  ALA A H    1 
ATOM   155   H HA   . ALA A 1 18  ? 85.417  88.707  126.256 1.00 49.02  ?  18  ALA A HA   1 
ATOM   156   H HB1  . ALA A 1 18  ? 85.984  87.666  128.273 1.00 49.02  ?  18  ALA A HB1  1 
ATOM   157   H HB2  . ALA A 1 18  ? 84.933  86.783  127.473 1.00 49.02  ?  18  ALA A HB2  1 
ATOM   158   H HB3  . ALA A 1 18  ? 86.471  86.384  127.469 1.00 49.02  ?  18  ALA A HB3  1 
ATOM   159   N N    . GLN A 1 19  ? 88.465  87.823  125.847 1.00 40.48  ?  19  GLN A N    1 
ATOM   160   C CA   . GLN A 1 19  ? 89.826  88.342  125.780 1.00 40.48  ?  19  GLN A CA   1 
ATOM   161   C C    . GLN A 1 19  ? 89.934  89.466  124.760 1.00 40.48  ?  19  GLN A C    1 
ATOM   162   O O    . GLN A 1 19  ? 90.641  90.450  124.988 1.00 40.48  ?  19  GLN A O    1 
ATOM   163   C CB   . GLN A 1 19  ? 90.797  87.212  125.441 1.00 40.48  ?  19  GLN A CB   1 
ATOM   164   C CG   . GLN A 1 19  ? 92.260  87.619  125.472 1.00 40.48  ?  19  GLN A CG   1 
ATOM   165   C CD   . GLN A 1 19  ? 93.166  86.489  125.918 1.00 40.48  ?  19  GLN A CD   1 
ATOM   166   O OE1  . GLN A 1 19  ? 93.101  86.040  127.063 1.00 40.48  ?  19  GLN A OE1  1 
ATOM   167   N NE2  . GLN A 1 19  ? 94.015  86.019  125.013 1.00 40.48  ?  19  GLN A NE2  1 
ATOM   168   H H    . GLN A 1 19  ? 88.385  87.001  125.606 1.00 40.48  ?  19  GLN A H    1 
ATOM   169   H HA   . GLN A 1 19  ? 90.071  88.699  126.648 1.00 40.48  ?  19  GLN A HA   1 
ATOM   170   H HB2  . GLN A 1 19  ? 90.676  86.493  126.081 1.00 40.48  ?  19  GLN A HB2  1 
ATOM   171   H HB3  . GLN A 1 19  ? 90.600  86.891  124.547 1.00 40.48  ?  19  GLN A HB3  1 
ATOM   172   H HG2  . GLN A 1 19  ? 92.532  87.891  124.582 1.00 40.48  ?  19  GLN A HG2  1 
ATOM   173   H HG3  . GLN A 1 19  ? 92.370  88.355  126.094 1.00 40.48  ?  19  GLN A HG3  1 
ATOM   174   H HE21 . GLN A 1 19  ? 94.030  86.357  124.222 1.00 40.48  ?  19  GLN A HE21 1 
ATOM   175   H HE22 . GLN A 1 19  ? 94.550  85.377  125.217 1.00 40.48  ?  19  GLN A HE22 1 
ATOM   176   N N    . ARG A 1 20  ? 89.245  89.336  123.624 1.00 46.10  ?  20  ARG A N    1 
ATOM   177   C CA   . ARG A 1 20  ? 89.250  90.406  122.631 1.00 46.10  ?  20  ARG A CA   1 
ATOM   178   C C    . ARG A 1 20  ? 88.592  91.669  123.175 1.00 46.10  ?  20  ARG A C    1 
ATOM   179   O O    . ARG A 1 20  ? 89.065  92.782  122.917 1.00 46.10  ?  20  ARG A O    1 
ATOM   180   C CB   . ARG A 1 20  ? 88.548  89.947  121.354 1.00 46.10  ?  20  ARG A CB   1 
ATOM   181   C CG   . ARG A 1 20  ? 89.379  89.011  120.492 1.00 46.10  ?  20  ARG A CG   1 
ATOM   182   C CD   . ARG A 1 20  ? 88.745  88.807  119.124 1.00 46.10  ?  20  ARG A CD   1 
ATOM   183   N NE   . ARG A 1 20  ? 89.746  88.538  118.091 1.00 46.10  ?  20  ARG A NE   1 
ATOM   184   C CZ   . ARG A 1 20  ? 89.956  89.288  117.011 1.00 46.10  ?  20  ARG A CZ   1 
ATOM   185   N NH1  . ARG A 1 20  ? 90.897  88.936  116.145 1.00 46.10  1  20  ARG A NH1  1 
ATOM   186   N NH2  . ARG A 1 20  ? 89.242  90.385  116.783 1.00 46.10  ?  20  ARG A NH2  1 
ATOM   187   H H    . ARG A 1 20  ? 88.774  88.649  123.409 1.00 46.10  ?  20  ARG A H    1 
ATOM   188   H HA   . ARG A 1 20  ? 90.169  90.622  122.406 1.00 46.10  ?  20  ARG A HA   1 
ATOM   189   H HB2  . ARG A 1 20  ? 87.733  89.481  121.596 1.00 46.10  ?  20  ARG A HB2  1 
ATOM   190   H HB3  . ARG A 1 20  ? 88.333  90.729  120.822 1.00 46.10  ?  20  ARG A HB3  1 
ATOM   191   H HG2  . ARG A 1 20  ? 90.262  89.391  120.367 1.00 46.10  ?  20  ARG A HG2  1 
ATOM   192   H HG3  . ARG A 1 20  ? 89.443  88.147  120.929 1.00 46.10  ?  20  ARG A HG3  1 
ATOM   193   H HD2  . ARG A 1 20  ? 88.154  88.040  119.168 1.00 46.10  ?  20  ARG A HD2  1 
ATOM   194   H HD3  . ARG A 1 20  ? 88.238  89.598  118.890 1.00 46.10  ?  20  ARG A HD3  1 
ATOM   195   H HE   . ARG A 1 20  ? 90.249  87.849  118.198 1.00 46.10  ?  20  ARG A HE   1 
ATOM   196   H HH11 . ARG A 1 20  ? 91.365  88.228  116.284 1.00 46.10  ?  20  ARG A HH11 1 
ATOM   197   H HH12 . ARG A 1 20  ? 91.040  89.416  115.446 1.00 46.10  ?  20  ARG A HH12 1 
ATOM   198   H HH21 . ARG A 1 20  ? 88.628  90.631  117.330 1.00 46.10  ?  20  ARG A HH21 1 
ATOM   199   H HH22 . ARG A 1 20  ? 89.396  90.854  116.079 1.00 46.10  ?  20  ARG A HH22 1 
ATOM   200   N N    . GLU A 1 21  ? 87.494  91.522  123.918 1.00 44.14  ?  21  GLU A N    1 
ATOM   201   C CA   . GLU A 1 21  ? 86.865  92.689  124.532 1.00 44.14  ?  21  GLU A CA   1 
ATOM   202   C C    . GLU A 1 21  ? 87.797  93.358  125.535 1.00 44.14  ?  21  GLU A C    1 
ATOM   203   O O    . GLU A 1 21  ? 87.916  94.593  125.557 1.00 44.14  ?  21  GLU A O    1 
ATOM   204   C CB   . GLU A 1 21  ? 85.557  92.283  125.211 1.00 44.14  ?  21  GLU A CB   1 
ATOM   205   C CG   . GLU A 1 21  ? 84.502  93.377  125.234 1.00 44.14  ?  21  GLU A CG   1 
ATOM   206   C CD   . GLU A 1 21  ? 83.272  92.983  126.028 1.00 44.14  ?  21  GLU A CD   1 
ATOM   207   O OE1  . GLU A 1 21  ? 83.154  91.795  126.395 1.00 44.14  ?  21  GLU A OE1  1 
ATOM   208   O OE2  . GLU A 1 21  ? 82.422  93.862  126.286 1.00 44.14  -1 21  GLU A OE2  1 
ATOM   209   H H    . GLU A 1 21  ? 87.102  90.773  124.080 1.00 44.14  ?  21  GLU A H    1 
ATOM   210   H HA   . GLU A 1 21  ? 86.656  93.335  123.839 1.00 44.14  ?  21  GLU A HA   1 
ATOM   211   H HB2  . GLU A 1 21  ? 85.183  91.523  124.738 1.00 44.14  ?  21  GLU A HB2  1 
ATOM   212   H HB3  . GLU A 1 21  ? 85.747  92.035  126.130 1.00 44.14  ?  21  GLU A HB3  1 
ATOM   213   H HG2  . GLU A 1 21  ? 84.880  94.172  125.640 1.00 44.14  ?  21  GLU A HG2  1 
ATOM   214   H HG3  . GLU A 1 21  ? 84.224  93.568  124.324 1.00 44.14  ?  21  GLU A HG3  1 
ATOM   215   N N    . ALA A 1 22  ? 88.470  92.560  126.368 1.00 38.15  ?  22  ALA A N    1 
ATOM   216   C CA   . ALA A 1 22  ? 89.438  93.120  127.305 1.00 38.15  ?  22  ALA A CA   1 
ATOM   217   C C    . ALA A 1 22  ? 90.570  93.818  126.563 1.00 38.15  ?  22  ALA A C    1 
ATOM   218   O O    . ALA A 1 22  ? 91.046  94.875  126.991 1.00 38.15  ?  22  ALA A O    1 
ATOM   219   C CB   . ALA A 1 22  ? 89.988  92.020  128.212 1.00 38.15  ?  22  ALA A CB   1 
ATOM   220   H H    . ALA A 1 22  ? 88.384  91.705  126.409 1.00 38.15  ?  22  ALA A H    1 
ATOM   221   H HA   . ALA A 1 22  ? 88.994  93.777  127.864 1.00 38.15  ?  22  ALA A HA   1 
ATOM   222   H HB1  . ALA A 1 22  ? 90.630  92.409  128.826 1.00 38.15  ?  22  ALA A HB1  1 
ATOM   223   H HB2  . ALA A 1 22  ? 89.254  91.623  128.708 1.00 38.15  ?  22  ALA A HB2  1 
ATOM   224   H HB3  . ALA A 1 22  ? 90.420  91.346  127.664 1.00 38.15  ?  22  ALA A HB3  1 
ATOM   225   N N    . ASN A 1 23  ? 91.018  93.234  125.450 1.00 34.26  ?  23  ASN A N    1 
ATOM   226   C CA   . ASN A 1 23  ? 92.073  93.845  124.652 1.00 34.26  ?  23  ASN A CA   1 
ATOM   227   C C    . ASN A 1 23  ? 91.620  95.181  124.081 1.00 34.26  ?  23  ASN A C    1 
ATOM   228   O O    . ASN A 1 23  ? 92.390  96.142  124.040 1.00 34.26  ?  23  ASN A O    1 
ATOM   229   C CB   . ASN A 1 23  ? 92.493  92.895  123.529 1.00 34.26  ?  23  ASN A CB   1 
ATOM   230   C CG   . ASN A 1 23  ? 93.726  93.375  122.790 1.00 34.26  ?  23  ASN A CG   1 
ATOM   231   O OD1  . ASN A 1 23  ? 94.271  94.438  123.090 1.00 34.26  ?  23  ASN A OD1  1 
ATOM   232   N ND2  . ASN A 1 23  ? 94.172  92.593  121.814 1.00 34.26  ?  23  ASN A ND2  1 
ATOM   233   H H    . ASN A 1 23  ? 90.726  92.487  125.139 1.00 34.26  ?  23  ASN A H    1 
ATOM   234   H HA   . ASN A 1 23  ? 92.846  94.005  125.216 1.00 34.26  ?  23  ASN A HA   1 
ATOM   235   H HB2  . ASN A 1 23  ? 92.690  92.024  123.909 1.00 34.26  ?  23  ASN A HB2  1 
ATOM   236   H HB3  . ASN A 1 23  ? 91.768  92.822  122.889 1.00 34.26  ?  23  ASN A HB3  1 
ATOM   237   H HD21 . ASN A 1 23  ? 93.765  91.858  121.632 1.00 34.26  ?  23  ASN A HD21 1 
ATOM   238   H HD22 . ASN A 1 23  ? 94.868  92.822  121.364 1.00 34.26  ?  23  ASN A HD22 1 
ATOM   239   N N    . LYS A 1 24  ? 90.371  95.255  123.618 1.00 35.89  ?  24  LYS A N    1 
ATOM   240   C CA   . LYS A 1 24  ? 89.849  96.520  123.106 1.00 35.89  ?  24  LYS A CA   1 
ATOM   241   C C    . LYS A 1 24  ? 89.810  97.579  124.201 1.00 35.89  ?  24  LYS A C    1 
ATOM   242   O O    . LYS A 1 24  ? 90.198  98.735  123.979 1.00 35.89  ?  24  LYS A O    1 
ATOM   243   C CB   . LYS A 1 24  ? 88.453  96.312  122.518 1.00 35.89  ?  24  LYS A CB   1 
ATOM   244   C CG   . LYS A 1 24  ? 88.433  96.113  121.011 1.00 35.89  ?  24  LYS A CG   1 
ATOM   245   C CD   . LYS A 1 24  ? 87.052  95.703  120.516 1.00 35.89  ?  24  LYS A CD   1 
ATOM   246   C CE   . LYS A 1 24  ? 86.002  96.762  120.822 1.00 35.89  ?  24  LYS A CE   1 
ATOM   247   N NZ   . LYS A 1 24  ? 84.691  96.451  120.187 1.00 35.89  1  24  LYS A NZ   1 
ATOM   248   H H    . LYS A 1 24  ? 89.817  94.598  123.590 1.00 35.89  ?  24  LYS A H    1 
ATOM   249   H HA   . LYS A 1 24  ? 90.430  96.839  122.398 1.00 35.89  ?  24  LYS A HA   1 
ATOM   250   H HB2  . LYS A 1 24  ? 88.054  95.528  122.926 1.00 35.89  ?  24  LYS A HB2  1 
ATOM   251   H HB3  . LYS A 1 24  ? 87.917  97.094  122.721 1.00 35.89  ?  24  LYS A HB3  1 
ATOM   252   H HG2  . LYS A 1 24  ? 88.676  96.945  120.575 1.00 35.89  ?  24  LYS A HG2  1 
ATOM   253   H HG3  . LYS A 1 24  ? 89.061  95.413  120.772 1.00 35.89  ?  24  LYS A HG3  1 
ATOM   254   H HD2  . LYS A 1 24  ? 87.082  95.576  119.555 1.00 35.89  ?  24  LYS A HD2  1 
ATOM   255   H HD3  . LYS A 1 24  ? 86.787  94.879  120.954 1.00 35.89  ?  24  LYS A HD3  1 
ATOM   256   H HE2  . LYS A 1 24  ? 85.865  96.809  121.781 1.00 35.89  ?  24  LYS A HE2  1 
ATOM   257   H HE3  . LYS A 1 24  ? 86.306  97.619  120.485 1.00 35.89  ?  24  LYS A HE3  1 
ATOM   258   H HZ1  . LYS A 1 24  ? 84.783  96.412  119.303 1.00 35.89  ?  24  LYS A HZ1  1 
ATOM   259   H HZ2  . LYS A 1 24  ? 84.099  97.084  120.388 1.00 35.89  ?  24  LYS A HZ2  1 
ATOM   260   H HZ3  . LYS A 1 24  ? 84.389  95.668  120.482 1.00 35.89  ?  24  LYS A HZ3  1 
ATOM   261   N N    . LYS A 1 25  ? 89.339  97.203  125.393 1.00 35.39  ?  25  LYS A N    1 
ATOM   262   C CA   . LYS A 1 25  ? 89.315  98.155  126.500 1.00 35.39  ?  25  LYS A CA   1 
ATOM   263   C C    . LYS A 1 25  ? 90.724  98.627  126.847 1.00 35.39  ?  25  LYS A C    1 
ATOM   264   O O    . LYS A 1 25  ? 90.955  99.826  127.060 1.00 35.39  ?  25  LYS A O    1 
ATOM   265   C CB   . LYS A 1 25  ? 88.645  97.523  127.719 1.00 35.39  ?  25  LYS A CB   1 
ATOM   266   C CG   . LYS A 1 25  ? 88.260  98.522  128.802 1.00 35.39  ?  25  LYS A CG   1 
ATOM   267   C CD   . LYS A 1 25  ? 87.337  97.907  129.849 1.00 35.39  ?  25  LYS A CD   1 
ATOM   268   C CE   . LYS A 1 25  ? 86.012  97.459  129.250 1.00 35.39  ?  25  LYS A CE   1 
ATOM   269   N NZ   . LYS A 1 25  ? 84.891  97.571  130.223 1.00 35.39  1  25  LYS A NZ   1 
ATOM   270   H H    . LYS A 1 25  ? 89.035  96.421  125.581 1.00 35.39  ?  25  LYS A H    1 
ATOM   271   H HA   . LYS A 1 25  ? 88.794  98.931  126.239 1.00 35.39  ?  25  LYS A HA   1 
ATOM   272   H HB2  . LYS A 1 25  ? 87.841  97.068  127.424 1.00 35.39  ?  25  LYS A HB2  1 
ATOM   273   H HB3  . LYS A 1 25  ? 89.258  96.882  128.113 1.00 35.39  ?  25  LYS A HB3  1 
ATOM   274   H HG2  . LYS A 1 25  ? 89.062  98.831  129.251 1.00 35.39  ?  25  LYS A HG2  1 
ATOM   275   H HG3  . LYS A 1 25  ? 87.796  99.271  128.394 1.00 35.39  ?  25  LYS A HG3  1 
ATOM   276   H HD2  . LYS A 1 25  ? 87.771  97.132  130.238 1.00 35.39  ?  25  LYS A HD2  1 
ATOM   277   H HD3  . LYS A 1 25  ? 87.151  98.566  130.536 1.00 35.39  ?  25  LYS A HD3  1 
ATOM   278   H HE2  . LYS A 1 25  ? 85.804  98.017  128.484 1.00 35.39  ?  25  LYS A HE2  1 
ATOM   279   H HE3  . LYS A 1 25  ? 86.084  96.531  128.977 1.00 35.39  ?  25  LYS A HE3  1 
ATOM   280   H HZ1  . LYS A 1 25  ? 85.056  97.064  130.936 1.00 35.39  ?  25  LYS A HZ1  1 
ATOM   281   H HZ2  . LYS A 1 25  ? 84.132  97.301  129.845 1.00 35.39  ?  25  LYS A HZ2  1 
ATOM   282   H HZ3  . LYS A 1 25  ? 84.799  98.417  130.485 1.00 35.39  ?  25  LYS A HZ3  1 
ATOM   283   N N    . ILE A 1 26  ? 91.678  97.696  126.899 1.00 30.91  ?  26  ILE A N    1 
ATOM   284   C CA   . ILE A 1 26  ? 93.054  98.054  127.219 1.00 30.91  ?  26  ILE A CA   1 
ATOM   285   C C    . ILE A 1 26  ? 93.639  98.945  126.132 1.00 30.91  ?  26  ILE A C    1 
ATOM   286   O O    . ILE A 1 26  ? 94.411  99.863  126.417 1.00 30.91  ?  26  ILE A O    1 
ATOM   287   C CB   . ILE A 1 26  ? 93.899  96.785  127.429 1.00 30.91  ?  26  ILE A CB   1 
ATOM   288   C CG1  . ILE A 1 26  ? 93.526  96.116  128.754 1.00 30.91  ?  26  ILE A CG1  1 
ATOM   289   C CG2  . ILE A 1 26  ? 95.384  97.122  127.403 1.00 30.91  ?  26  ILE A CG2  1 
ATOM   290   C CD1  . ILE A 1 26  ? 93.986  94.677  128.866 1.00 30.91  ?  26  ILE A CD1  1 
ATOM   291   H H    . ILE A 1 26  ? 91.553  96.857  126.755 1.00 30.91  ?  26  ILE A H    1 
ATOM   292   H HA   . ILE A 1 26  ? 93.062  98.556  128.049 1.00 30.91  ?  26  ILE A HA   1 
ATOM   293   H HB   . ILE A 1 26  ? 93.711  96.166  126.706 1.00 30.91  ?  26  ILE A HB   1 
ATOM   294   H HG12 . ILE A 1 26  ? 93.933  96.614  129.480 1.00 30.91  ?  26  ILE A HG12 1 
ATOM   295   H HG13 . ILE A 1 26  ? 92.561  96.126  128.848 1.00 30.91  ?  26  ILE A HG13 1 
ATOM   296   H HG21 . ILE A 1 26  ? 95.670  97.236  126.483 1.00 30.91  ?  26  ILE A HG21 1 
ATOM   297   H HG22 . ILE A 1 26  ? 95.881  96.397  127.812 1.00 30.91  ?  26  ILE A HG22 1 
ATOM   298   H HG23 . ILE A 1 26  ? 95.531  97.941  127.902 1.00 30.91  ?  26  ILE A HG23 1 
ATOM   299   H HD11 . ILE A 1 26  ? 93.626  94.295  129.681 1.00 30.91  ?  26  ILE A HD11 1 
ATOM   300   H HD12 . ILE A 1 26  ? 94.955  94.654  128.890 1.00 30.91  ?  26  ILE A HD12 1 
ATOM   301   H HD13 . ILE A 1 26  ? 93.661  94.182  128.097 1.00 30.91  ?  26  ILE A HD13 1 
ATOM   302   N N    . GLU A 1 27  ? 93.292  98.685  124.870 1.00 32.05  ?  27  GLU A N    1 
ATOM   303   C CA   . GLU A 1 27  ? 93.778  99.524  123.780 1.00 32.05  ?  27  GLU A CA   1 
ATOM   304   C C    . GLU A 1 27  ? 93.246  100.943 123.903 1.00 32.05  ?  27  GLU A C    1 
ATOM   305   O O    . GLU A 1 27  ? 93.987  101.909 123.695 1.00 32.05  ?  27  GLU A O    1 
ATOM   306   C CB   . GLU A 1 27  ? 93.378  98.920  122.431 1.00 32.05  ?  27  GLU A CB   1 
ATOM   307   C CG   . GLU A 1 27  ? 94.219  97.728  121.980 1.00 32.05  ?  27  GLU A CG   1 
ATOM   308   C CD   . GLU A 1 27  ? 95.710  97.987  122.061 1.00 32.05  ?  27  GLU A CD   1 
ATOM   309   O OE1  . GLU A 1 27  ? 96.298  97.748  123.135 1.00 32.05  ?  27  GLU A OE1  1 
ATOM   310   O OE2  . GLU A 1 27  ? 96.293  98.434  121.050 1.00 32.05  -1 27  GLU A OE2  1 
ATOM   311   H H    . GLU A 1 27  ? 92.782  98.038  124.623 1.00 32.05  ?  27  GLU A H    1 
ATOM   312   H HA   . GLU A 1 27  ? 94.744  99.572  123.829 1.00 32.05  ?  27  GLU A HA   1 
ATOM   313   H HB2  . GLU A 1 27  ? 92.457  98.623  122.488 1.00 32.05  ?  27  GLU A HB2  1 
ATOM   314   H HB3  . GLU A 1 27  ? 93.457  99.607  121.751 1.00 32.05  ?  27  GLU A HB3  1 
ATOM   315   H HG2  . GLU A 1 27  ? 94.020  96.967  122.546 1.00 32.05  ?  27  GLU A HG2  1 
ATOM   316   H HG3  . GLU A 1 27  ? 94.001  97.519  121.058 1.00 32.05  ?  27  GLU A HG3  1 
ATOM   317   N N    . LYS A 1 28  ? 91.964  101.093 124.238 1.00 33.71  ?  28  LYS A N    1 
ATOM   318   C CA   . LYS A 1 28  ? 91.418  102.435 124.432 1.00 33.71  ?  28  LYS A CA   1 
ATOM   319   C C    . LYS A 1 28  ? 92.112  103.146 125.590 1.00 33.71  ?  28  LYS A C    1 
ATOM   320   O O    . LYS A 1 28  ? 92.485  104.327 125.481 1.00 33.71  ?  28  LYS A O    1 
ATOM   321   C CB   . LYS A 1 28  ? 89.911  102.356 124.674 1.00 33.71  ?  28  LYS A CB   1 
ATOM   322   C CG   . LYS A 1 28  ? 89.158  103.617 124.280 1.00 33.71  ?  28  LYS A CG   1 
ATOM   323   C CD   . LYS A 1 28  ? 87.922  103.836 125.141 1.00 33.71  ?  28  LYS A CD   1 
ATOM   324   C CE   . LYS A 1 28  ? 86.859  102.777 124.888 1.00 33.71  ?  28  LYS A CE   1 
ATOM   325   N NZ   . LYS A 1 28  ? 85.834  102.748 125.968 1.00 33.71  1  28  LYS A NZ   1 
ATOM   326   H H    . LYS A 1 28  ? 91.403  100.452 124.357 1.00 33.71  ?  28  LYS A H    1 
ATOM   327   H HA   . LYS A 1 28  ? 91.566  102.956 123.627 1.00 33.71  ?  28  LYS A HA   1 
ATOM   328   H HB2  . LYS A 1 28  ? 89.549  101.621 124.155 1.00 33.71  ?  28  LYS A HB2  1 
ATOM   329   H HB3  . LYS A 1 28  ? 89.755  102.200 125.618 1.00 33.71  ?  28  LYS A HB3  1 
ATOM   330   H HG2  . LYS A 1 28  ? 89.743  104.382 124.388 1.00 33.71  ?  28  LYS A HG2  1 
ATOM   331   H HG3  . LYS A 1 28  ? 88.873  103.542 123.356 1.00 33.71  ?  28  LYS A HG3  1 
ATOM   332   H HD2  . LYS A 1 28  ? 88.173  103.796 126.077 1.00 33.71  ?  28  LYS A HD2  1 
ATOM   333   H HD3  . LYS A 1 28  ? 87.540  104.704 124.935 1.00 33.71  ?  28  LYS A HD3  1 
ATOM   334   H HE2  . LYS A 1 28  ? 86.409  102.973 124.051 1.00 33.71  ?  28  LYS A HE2  1 
ATOM   335   H HE3  . LYS A 1 28  ? 87.276  101.903 124.846 1.00 33.71  ?  28  LYS A HE3  1 
ATOM   336   H HZ1  . LYS A 1 28  ? 85.228  102.120 125.795 1.00 33.71  ?  28  LYS A HZ1  1 
ATOM   337   H HZ2  . LYS A 1 28  ? 86.221  102.569 126.749 1.00 33.71  ?  28  LYS A HZ2  1 
ATOM   338   H HZ3  . LYS A 1 28  ? 85.426  103.538 126.021 1.00 33.71  ?  28  LYS A HZ3  1 
ATOM   339   N N    . GLN A 1 29  ? 92.305  102.439 126.706 1.00 32.99  ?  29  GLN A N    1 
ATOM   340   C CA   . GLN A 1 29  ? 92.968  103.046 127.856 1.00 32.99  ?  29  GLN A CA   1 
ATOM   341   C C    . GLN A 1 29  ? 94.398  103.447 127.513 1.00 32.99  ?  29  GLN A C    1 
ATOM   342   O O    . GLN A 1 29  ? 94.864  104.525 127.900 1.00 32.99  ?  29  GLN A O    1 
ATOM   343   C CB   . GLN A 1 29  ? 92.947  102.080 129.042 1.00 32.99  ?  29  GLN A CB   1 
ATOM   344   C CG   . GLN A 1 29  ? 93.601  102.626 130.303 1.00 32.99  ?  29  GLN A CG   1 
ATOM   345   C CD   . GLN A 1 29  ? 92.991  103.938 130.757 1.00 32.99  ?  29  GLN A CD   1 
ATOM   346   O OE1  . GLN A 1 29  ? 91.771  104.094 130.777 1.00 32.99  ?  29  GLN A OE1  1 
ATOM   347   N NE2  . GLN A 1 29  ? 93.841  104.890 131.125 1.00 32.99  ?  29  GLN A NE2  1 
ATOM   348   H H    . GLN A 1 29  ? 92.066  101.621 126.819 1.00 32.99  ?  29  GLN A H    1 
ATOM   349   H HA   . GLN A 1 29  ? 92.484  103.848 128.109 1.00 32.99  ?  29  GLN A HA   1 
ATOM   350   H HB2  . GLN A 1 29  ? 92.024  101.870 129.255 1.00 32.99  ?  29  GLN A HB2  1 
ATOM   351   H HB3  . GLN A 1 29  ? 93.418  101.270 128.792 1.00 32.99  ?  29  GLN A HB3  1 
ATOM   352   H HG2  . GLN A 1 29  ? 93.491  101.981 131.019 1.00 32.99  ?  29  GLN A HG2  1 
ATOM   353   H HG3  . GLN A 1 29  ? 94.545  102.775 130.135 1.00 32.99  ?  29  GLN A HG3  1 
ATOM   354   H HE21 . GLN A 1 29  ? 94.688  104.744 131.098 1.00 32.99  ?  29  GLN A HE21 1 
ATOM   355   H HE22 . GLN A 1 29  ? 93.544  105.652 131.390 1.00 32.99  ?  29  GLN A HE22 1 
ATOM   356   N N    . LEU A 1 30  ? 95.111  102.589 126.779 1.00 29.36  ?  30  LEU A N    1 
ATOM   357   C CA   . LEU A 1 30  ? 96.487  102.893 126.408 1.00 29.36  ?  30  LEU A CA   1 
ATOM   358   C C    . LEU A 1 30  ? 96.546  104.032 125.401 1.00 29.36  ?  30  LEU A C    1 
ATOM   359   O O    . LEU A 1 30  ? 97.510  104.799 125.386 1.00 29.36  ?  30  LEU A O    1 
ATOM   360   C CB   . LEU A 1 30  ? 97.169  101.645 125.845 1.00 29.36  ?  30  LEU A CB   1 
ATOM   361   C CG   . LEU A 1 30  ? 97.490  100.514 126.828 1.00 29.36  ?  30  LEU A CG   1 
ATOM   362   C CD1  . LEU A 1 30  ? 98.343  99.454  126.149 1.00 29.36  ?  30  LEU A CD1  1 
ATOM   363   C CD2  . LEU A 1 30  ? 98.188  101.035 128.076 1.00 29.36  ?  30  LEU A CD2  1 
ATOM   364   H H    . LEU A 1 30  ? 94.821  101.833 126.489 1.00 29.36  ?  30  LEU A H    1 
ATOM   365   H HA   . LEU A 1 30  ? 96.970  103.179 127.198 1.00 29.36  ?  30  LEU A HA   1 
ATOM   366   H HB2  . LEU A 1 30  ? 96.594  101.271 125.160 1.00 29.36  ?  30  LEU A HB2  1 
ATOM   367   H HB3  . LEU A 1 30  ? 98.008  101.917 125.442 1.00 29.36  ?  30  LEU A HB3  1 
ATOM   368   H HG   . LEU A 1 30  ? 96.663  100.093 127.108 1.00 29.36  ?  30  LEU A HG   1 
ATOM   369   H HD11 . LEU A 1 30  ? 97.863  99.109  125.380 1.00 29.36  ?  30  LEU A HD11 1 
ATOM   370   H HD12 . LEU A 1 30  ? 98.519  98.738  126.779 1.00 29.36  ?  30  LEU A HD12 1 
ATOM   371   H HD13 . LEU A 1 30  ? 99.178  99.857  125.864 1.00 29.36  ?  30  LEU A HD13 1 
ATOM   372   H HD21 . LEU A 1 30  ? 97.546  101.519 128.619 1.00 29.36  ?  30  LEU A HD21 1 
ATOM   373   H HD22 . LEU A 1 30  ? 98.540  100.282 128.577 1.00 29.36  ?  30  LEU A HD22 1 
ATOM   374   H HD23 . LEU A 1 30  ? 98.912  101.623 127.811 1.00 29.36  ?  30  LEU A HD23 1 
ATOM   375   N N    . GLN A 1 31  ? 95.529  104.158 124.547 1.00 32.41  ?  31  GLN A N    1 
ATOM   376   C CA   . GLN A 1 31  ? 95.479  105.298 123.638 1.00 32.41  ?  31  GLN A CA   1 
ATOM   377   C C    . GLN A 1 31  ? 95.325  106.600 124.411 1.00 32.41  ?  31  GLN A C    1 
ATOM   378   O O    . GLN A 1 31  ? 96.012  107.589 124.125 1.00 32.41  ?  31  GLN A O    1 
ATOM   379   C CB   . GLN A 1 31  ? 94.328  105.125 122.642 1.00 32.41  ?  31  GLN A CB   1 
ATOM   380   C CG   . GLN A 1 31  ? 94.457  105.903 121.325 1.00 32.41  ?  31  GLN A CG   1 
ATOM   381   C CD   . GLN A 1 31  ? 95.841  105.838 120.694 1.00 32.41  ?  31  GLN A CD   1 
ATOM   382   O OE1  . GLN A 1 31  ? 96.638  104.949 120.993 1.00 32.41  ?  31  GLN A OE1  1 
ATOM   383   N NE2  . GLN A 1 31  ? 96.129  106.789 119.813 1.00 32.41  ?  31  GLN A NE2  1 
ATOM   384   H H    . GLN A 1 31  ? 94.871  103.609 124.476 1.00 32.41  ?  31  GLN A H    1 
ATOM   385   H HA   . GLN A 1 31  ? 96.320  105.341 123.165 1.00 32.41  ?  31  GLN A HA   1 
ATOM   386   H HB2  . GLN A 1 31  ? 94.258  104.184 122.417 1.00 32.41  ?  31  GLN A HB2  1 
ATOM   387   H HB3  . GLN A 1 31  ? 93.508  105.416 123.070 1.00 32.41  ?  31  GLN A HB3  1 
ATOM   388   H HG2  . GLN A 1 31  ? 93.824  105.540 120.686 1.00 32.41  ?  31  GLN A HG2  1 
ATOM   389   H HG3  . GLN A 1 31  ? 94.254  106.836 121.494 1.00 32.41  ?  31  GLN A HG3  1 
ATOM   390   H HE21 . GLN A 1 31  ? 95.548  107.395 119.629 1.00 32.41  ?  31  GLN A HE21 1 
ATOM   391   H HE22 . GLN A 1 31  ? 96.898  106.799 119.428 1.00 32.41  ?  31  GLN A HE22 1 
ATOM   392   N N    . LYS A 1 32  ? 94.433  106.617 125.405 1.00 33.57  ?  32  LYS A N    1 
ATOM   393   C CA   . LYS A 1 32  ? 94.304  107.809 126.241 1.00 33.57  ?  32  LYS A CA   1 
ATOM   394   C C    . LYS A 1 32  ? 95.601  108.099 126.992 1.00 33.57  ?  32  LYS A C    1 
ATOM   395   O O    . LYS A 1 32  ? 96.031  109.259 127.093 1.00 33.57  ?  32  LYS A O    1 
ATOM   396   C CB   . LYS A 1 32  ? 93.141  107.643 127.219 1.00 33.57  ?  32  LYS A CB   1 
ATOM   397   C CG   . LYS A 1 32  ? 91.778  107.929 126.609 1.00 33.57  ?  32  LYS A CG   1 
ATOM   398   C CD   . LYS A 1 32  ? 90.713  106.981 127.139 1.00 33.57  ?  32  LYS A CD   1 
ATOM   399   C CE   . LYS A 1 32  ? 89.400  107.134 126.383 1.00 33.57  ?  32  LYS A CE   1 
ATOM   400   N NZ   . LYS A 1 32  ? 89.572  107.026 124.907 1.00 33.57  1  32  LYS A NZ   1 
ATOM   401   H H    . LYS A 1 32  ? 93.906  105.969 125.611 1.00 33.57  ?  32  LYS A H    1 
ATOM   402   H HA   . LYS A 1 32  ? 94.111  108.572 125.673 1.00 33.57  ?  32  LYS A HA   1 
ATOM   403   H HB2  . LYS A 1 32  ? 93.137  106.729 127.544 1.00 33.57  ?  32  LYS A HB2  1 
ATOM   404   H HB3  . LYS A 1 32  ? 93.268  108.255 127.961 1.00 33.57  ?  32  LYS A HB3  1 
ATOM   405   H HG2  . LYS A 1 32  ? 91.514  108.836 126.831 1.00 33.57  ?  32  LYS A HG2  1 
ATOM   406   H HG3  . LYS A 1 32  ? 91.835  107.822 125.647 1.00 33.57  ?  32  LYS A HG3  1 
ATOM   407   H HD2  . LYS A 1 32  ? 91.016  106.066 127.036 1.00 33.57  ?  32  LYS A HD2  1 
ATOM   408   H HD3  . LYS A 1 32  ? 90.548  107.177 128.075 1.00 33.57  ?  32  LYS A HD3  1 
ATOM   409   H HE2  . LYS A 1 32  ? 88.789  106.437 126.666 1.00 33.57  ?  32  LYS A HE2  1 
ATOM   410   H HE3  . LYS A 1 32  ? 89.023  108.006 126.578 1.00 33.57  ?  32  LYS A HE3  1 
ATOM   411   H HZ1  . LYS A 1 32  ? 89.904  107.786 124.584 1.00 33.57  ?  32  LYS A HZ1  1 
ATOM   412   H HZ2  . LYS A 1 32  ? 88.787  106.866 124.521 1.00 33.57  ?  32  LYS A HZ2  1 
ATOM   413   H HZ3  . LYS A 1 32  ? 90.130  106.361 124.714 1.00 33.57  ?  32  LYS A HZ3  1 
ATOM   414   N N    . ASP A 1 33  ? 96.237  107.054 127.528 1.00 32.64  ?  33  ASP A N    1 
ATOM   415   C CA   . ASP A 1 33  ? 97.498  107.233 128.238 1.00 32.64  ?  33  ASP A CA   1 
ATOM   416   C C    . ASP A 1 33  ? 98.582  107.777 127.317 1.00 32.64  ?  33  ASP A C    1 
ATOM   417   O O    . ASP A 1 33  ? 99.357  108.647 127.721 1.00 32.64  ?  33  ASP A O    1 
ATOM   418   C CB   . ASP A 1 33  ? 97.939  105.907 128.854 1.00 32.64  ?  33  ASP A CB   1 
ATOM   419   C CG   . ASP A 1 33  ? 97.155  105.556 130.104 1.00 32.64  ?  33  ASP A CG   1 
ATOM   420   O OD1  . ASP A 1 33  ? 96.362  106.401 130.569 1.00 32.64  ?  33  ASP A OD1  1 
ATOM   421   O OD2  . ASP A 1 33  ? 97.328  104.432 130.618 1.00 32.64  -1 33  ASP A OD2  1 
ATOM   422   H H    . ASP A 1 33  ? 95.959  106.241 127.494 1.00 32.64  ?  33  ASP A H    1 
ATOM   423   H HA   . ASP A 1 33  ? 97.367  107.865 128.959 1.00 32.64  ?  33  ASP A HA   1 
ATOM   424   H HB2  . ASP A 1 33  ? 97.806  105.197 128.206 1.00 32.64  ?  33  ASP A HB2  1 
ATOM   425   H HB3  . ASP A 1 33  ? 98.877  105.966 129.094 1.00 32.64  ?  33  ASP A HB3  1 
ATOM   426   N N    . LYS A 1 34  ? 98.651  107.278 126.083 1.00 30.88  ?  34  LYS A N    1 
ATOM   427   C CA   . LYS A 1 34  ? 99.604  107.792 125.108 1.00 30.88  ?  34  LYS A CA   1 
ATOM   428   C C    . LYS A 1 34  ? 99.331  109.256 124.795 1.00 30.88  ?  34  LYS A C    1 
ATOM   429   O O    . LYS A 1 34  ? 100.263 110.066 124.704 1.00 30.88  ?  34  LYS A O    1 
ATOM   430   C CB   . LYS A 1 34  ? 99.523  106.951 123.835 1.00 30.88  ?  34  LYS A CB   1 
ATOM   431   C CG   . LYS A 1 34  ? 100.595 107.228 122.802 1.00 30.88  ?  34  LYS A CG   1 
ATOM   432   C CD   . LYS A 1 34  ? 100.464 106.244 121.653 1.00 30.88  ?  34  LYS A CD   1 
ATOM   433   C CE   . LYS A 1 34  ? 101.640 106.307 120.702 1.00 30.88  ?  34  LYS A CE   1 
ATOM   434   N NZ   . LYS A 1 34  ? 101.522 105.262 119.650 1.00 30.88  1  34  LYS A NZ   1 
ATOM   435   H H    . LYS A 1 34  ? 98.155  106.640 125.788 1.00 30.88  ?  34  LYS A H    1 
ATOM   436   H HA   . LYS A 1 34  ? 100.502 107.719 125.466 1.00 30.88  ?  34  LYS A HA   1 
ATOM   437   H HB2  . LYS A 1 34  ? 99.592  106.015 124.082 1.00 30.88  ?  34  LYS A HB2  1 
ATOM   438   H HB3  . LYS A 1 34  ? 98.664  107.112 123.414 1.00 30.88  ?  34  LYS A HB3  1 
ATOM   439   H HG2  . LYS A 1 34  ? 100.486 108.126 122.454 1.00 30.88  ?  34  LYS A HG2  1 
ATOM   440   H HG3  . LYS A 1 34  ? 101.471 107.120 123.204 1.00 30.88  ?  34  LYS A HG3  1 
ATOM   441   H HD2  . LYS A 1 34  ? 100.414 105.343 122.010 1.00 30.88  ?  34  LYS A HD2  1 
ATOM   442   H HD3  . LYS A 1 34  ? 99.659  106.448 121.151 1.00 30.88  ?  34  LYS A HD3  1 
ATOM   443   H HE2  . LYS A 1 34  ? 101.659 107.176 120.270 1.00 30.88  ?  34  LYS A HE2  1 
ATOM   444   H HE3  . LYS A 1 34  ? 102.462 106.155 121.194 1.00 30.88  ?  34  LYS A HE3  1 
ATOM   445   H HZ1  . LYS A 1 34  ? 102.179 105.350 119.060 1.00 30.88  ?  34  LYS A HZ1  1 
ATOM   446   H HZ2  . LYS A 1 34  ? 100.742 105.344 119.228 1.00 30.88  ?  34  LYS A HZ2  1 
ATOM   447   H HZ3  . LYS A 1 34  ? 101.567 104.453 120.018 1.00 30.88  ?  34  LYS A HZ3  1 
ATOM   448   N N    . GLN A 1 35  ? 98.057  109.613 124.623 1.00 34.27  ?  35  GLN A N    1 
ATOM   449   C CA   . GLN A 1 35  ? 97.716  110.998 124.319 1.00 34.27  ?  35  GLN A CA   1 
ATOM   450   C C    . GLN A 1 35  ? 98.160  111.926 125.441 1.00 34.27  ?  35  GLN A C    1 
ATOM   451   O O    . GLN A 1 35  ? 98.738  112.991 125.191 1.00 34.27  ?  35  GLN A O    1 
ATOM   452   C CB   . GLN A 1 35  ? 96.212  111.127 124.077 1.00 34.27  ?  35  GLN A CB   1 
ATOM   453   C CG   . GLN A 1 35  ? 95.771  112.531 123.696 1.00 34.27  ?  35  GLN A CG   1 
ATOM   454   C CD   . GLN A 1 35  ? 94.383  112.562 123.089 1.00 34.27  ?  35  GLN A CD   1 
ATOM   455   O OE1  . GLN A 1 35  ? 93.595  111.632 123.262 1.00 34.27  ?  35  GLN A OE1  1 
ATOM   456   N NE2  . GLN A 1 35  ? 94.075  113.638 122.373 1.00 34.27  ?  35  GLN A NE2  1 
ATOM   457   H H    . GLN A 1 35  ? 97.384  109.081 124.676 1.00 34.27  ?  35  GLN A H    1 
ATOM   458   H HA   . GLN A 1 35  ? 98.175  111.267 123.508 1.00 34.27  ?  35  GLN A HA   1 
ATOM   459   H HB2  . GLN A 1 35  ? 95.959  110.530 123.356 1.00 34.27  ?  35  GLN A HB2  1 
ATOM   460   H HB3  . GLN A 1 35  ? 95.743  110.879 124.889 1.00 34.27  ?  35  GLN A HB3  1 
ATOM   461   H HG2  . GLN A 1 35  ? 95.764  113.087 124.491 1.00 34.27  ?  35  GLN A HG2  1 
ATOM   462   H HG3  . GLN A 1 35  ? 96.392  112.891 123.044 1.00 34.27  ?  35  GLN A HG3  1 
ATOM   463   H HE21 . GLN A 1 35  ? 94.652  114.268 122.274 1.00 34.27  ?  35  GLN A HE21 1 
ATOM   464   H HE22 . GLN A 1 35  ? 93.300  113.704 122.007 1.00 34.27  ?  35  GLN A HE22 1 
ATOM   465   N N    . VAL A 1 36  ? 97.900  111.540 126.692 1.00 31.80  ?  36  VAL A N    1 
ATOM   466   C CA   . VAL A 1 36  ? 98.304  112.390 127.812 1.00 31.80  ?  36  VAL A CA   1 
ATOM   467   C C    . VAL A 1 36  ? 99.824  112.409 127.953 1.00 31.80  ?  36  VAL A C    1 
ATOM   468   O O    . VAL A 1 36  ? 100.417 113.440 128.294 1.00 31.80  ?  36  VAL A O    1 
ATOM   469   C CB   . VAL A 1 36  ? 97.611  111.943 129.114 1.00 31.80  ?  36  VAL A CB   1 
ATOM   470   C CG1  . VAL A 1 36  ? 98.060  110.556 129.525 1.00 31.80  ?  36  VAL A CG1  1 
ATOM   471   C CG2  . VAL A 1 36  ? 97.880  112.946 130.229 1.00 31.80  ?  36  VAL A CG2  1 
ATOM   472   H H    . VAL A 1 36  ? 97.502  110.811 126.914 1.00 31.80  ?  36  VAL A H    1 
ATOM   473   H HA   . VAL A 1 36  ? 98.017  113.298 127.627 1.00 31.80  ?  36  VAL A HA   1 
ATOM   474   H HB   . VAL A 1 36  ? 96.653  111.914 128.966 1.00 31.80  ?  36  VAL A HB   1 
ATOM   475   H HG11 . VAL A 1 36  ? 97.610  110.312 130.349 1.00 31.80  ?  36  VAL A HG11 1 
ATOM   476   H HG12 . VAL A 1 36  ? 97.814  109.941 128.822 1.00 31.80  ?  36  VAL A HG12 1 
ATOM   477   H HG13 . VAL A 1 36  ? 99.020  110.549 129.661 1.00 31.80  ?  36  VAL A HG13 1 
ATOM   478   H HG21 . VAL A 1 36  ? 98.825  112.931 130.447 1.00 31.80  ?  36  VAL A HG21 1 
ATOM   479   H HG22 . VAL A 1 36  ? 97.357  112.699 131.007 1.00 31.80  ?  36  VAL A HG22 1 
ATOM   480   H HG23 . VAL A 1 36  ? 97.623  113.831 129.925 1.00 31.80  ?  36  VAL A HG23 1 
ATOM   481   N N    . TYR A 1 37  ? 100.478 111.274 127.694 1.00 28.12  ?  37  TYR A N    1 
ATOM   482   C CA   . TYR A 1 37  ? 101.923 111.180 127.876 1.00 28.12  ?  37  TYR A CA   1 
ATOM   483   C C    . TYR A 1 37  ? 102.669 112.047 126.869 1.00 28.12  ?  37  TYR A C    1 
ATOM   484   O O    . TYR A 1 37  ? 103.586 112.793 127.233 1.00 28.12  ?  37  TYR A O    1 
ATOM   485   C CB   . TYR A 1 37  ? 102.355 109.717 127.757 1.00 28.12  ?  37  TYR A CB   1 
ATOM   486   C CG   . TYR A 1 37  ? 103.851 109.496 127.751 1.00 28.12  ?  37  TYR A CG   1 
ATOM   487   C CD1  . TYR A 1 37  ? 104.566 109.414 128.938 1.00 28.12  ?  37  TYR A CD1  1 
ATOM   488   C CD2  . TYR A 1 37  ? 104.545 109.354 126.557 1.00 28.12  ?  37  TYR A CD2  1 
ATOM   489   C CE1  . TYR A 1 37  ? 105.932 109.206 128.935 1.00 28.12  ?  37  TYR A CE1  1 
ATOM   490   C CE2  . TYR A 1 37  ? 105.910 109.146 126.544 1.00 28.12  ?  37  TYR A CE2  1 
ATOM   491   C CZ   . TYR A 1 37  ? 106.599 109.072 127.736 1.00 28.12  ?  37  TYR A CZ   1 
ATOM   492   O OH   . TYR A 1 37  ? 107.959 108.865 127.728 1.00 28.12  ?  37  TYR A OH   1 
ATOM   493   H H    . TYR A 1 37  ? 100.109 110.550 127.414 1.00 28.12  ?  37  TYR A H    1 
ATOM   494   H HA   . TYR A 1 37  ? 102.152 111.490 128.767 1.00 28.12  ?  37  TYR A HA   1 
ATOM   495   H HB2  . TYR A 1 37  ? 101.989 109.225 128.509 1.00 28.12  ?  37  TYR A HB2  1 
ATOM   496   H HB3  . TYR A 1 37  ? 102.002 109.357 126.929 1.00 28.12  ?  37  TYR A HB3  1 
ATOM   497   H HD1  . TYR A 1 37  ? 104.119 109.504 129.748 1.00 28.12  ?  37  TYR A HD1  1 
ATOM   498   H HD2  . TYR A 1 37  ? 104.083 109.404 125.751 1.00 28.12  ?  37  TYR A HD2  1 
ATOM   499   H HE1  . TYR A 1 37  ? 106.399 109.155 129.738 1.00 28.12  ?  37  TYR A HE1  1 
ATOM   500   H HE2  . TYR A 1 37  ? 106.363 109.056 125.737 1.00 28.12  ?  37  TYR A HE2  1 
ATOM   501   H HH   . TYR A 1 37  ? 108.234 108.796 126.937 1.00 28.12  ?  37  TYR A HH   1 
ATOM   502   N N    . ARG A 1 38  ? 102.290 111.961 125.591 1.00 31.50  ?  38  ARG A N    1 
ATOM   503   C CA   . ARG A 1 38  ? 103.002 112.717 124.565 1.00 31.50  ?  38  ARG A CA   1 
ATOM   504   C C    . ARG A 1 38  ? 102.873 114.220 124.781 1.00 31.50  ?  38  ARG A C    1 
ATOM   505   O O    . ARG A 1 38  ? 103.727 114.985 124.319 1.00 31.50  ?  38  ARG A O    1 
ATOM   506   C CB   . ARG A 1 38  ? 102.481 112.337 123.176 1.00 31.50  ?  38  ARG A CB   1 
ATOM   507   C CG   . ARG A 1 38  ? 102.951 110.982 122.612 1.00 31.50  ?  38  ARG A CG   1 
ATOM   508   C CD   . ARG A 1 38  ? 104.463 110.740 122.689 1.00 31.50  ?  38  ARG A CD   1 
ATOM   509   N NE   . ARG A 1 38  ? 104.782 109.320 122.813 1.00 31.50  ?  38  ARG A NE   1 
ATOM   510   C CZ   . ARG A 1 38  ? 104.813 108.462 121.797 1.00 31.50  ?  38  ARG A CZ   1 
ATOM   511   N NH1  . ARG A 1 38  ? 105.115 107.190 122.015 1.00 31.50  1  38  ARG A NH1  1 
ATOM   512   N NH2  . ARG A 1 38  ? 104.541 108.870 120.563 1.00 31.50  ?  38  ARG A NH2  1 
ATOM   513   H H    . ARG A 1 38  ? 101.639 111.482 125.300 1.00 31.50  ?  38  ARG A H    1 
ATOM   514   H HA   . ARG A 1 38  ? 103.943 112.511 124.627 1.00 31.50  ?  38  ARG A HA   1 
ATOM   515   H HB2  . ARG A 1 38  ? 101.512 112.314 123.210 1.00 31.50  ?  38  ARG A HB2  1 
ATOM   516   H HB3  . ARG A 1 38  ? 102.763 113.022 122.549 1.00 31.50  ?  38  ARG A HB3  1 
ATOM   517   H HG2  . ARG A 1 38  ? 102.516 110.273 123.111 1.00 31.50  ?  38  ARG A HG2  1 
ATOM   518   H HG3  . ARG A 1 38  ? 102.693 110.929 121.679 1.00 31.50  ?  38  ARG A HG3  1 
ATOM   519   H HD2  . ARG A 1 38  ? 104.877 111.072 121.877 1.00 31.50  ?  38  ARG A HD2  1 
ATOM   520   H HD3  . ARG A 1 38  ? 104.848 111.184 123.455 1.00 31.50  ?  38  ARG A HD3  1 
ATOM   521   H HE   . ARG A 1 38  ? 105.004 109.026 123.591 1.00 31.50  ?  38  ARG A HE   1 
ATOM   522   H HH11 . ARG A 1 38  ? 105.291 106.921 122.813 1.00 31.50  ?  38  ARG A HH11 1 
ATOM   523   H HH12 . ARG A 1 38  ? 105.135 106.634 121.359 1.00 31.50  ?  38  ARG A HH12 1 
ATOM   524   H HH21 . ARG A 1 38  ? 104.344 109.692 120.411 1.00 31.50  ?  38  ARG A HH21 1 
ATOM   525   H HH22 . ARG A 1 38  ? 104.563 108.308 119.913 1.00 31.50  ?  38  ARG A HH22 1 
ATOM   526   N N    . ALA A 1 39  ? 101.823 114.661 125.474 1.00 31.47  ?  39  ALA A N    1 
ATOM   527   C CA   . ALA A 1 39  ? 101.623 116.081 125.732 1.00 31.47  ?  39  ALA A CA   1 
ATOM   528   C C    . ALA A 1 39  ? 102.401 116.583 126.941 1.00 31.47  ?  39  ALA A C    1 
ATOM   529   O O    . ALA A 1 39  ? 102.369 117.788 127.217 1.00 31.47  ?  39  ALA A O    1 
ATOM   530   C CB   . ALA A 1 39  ? 100.133 116.370 125.930 1.00 31.47  ?  39  ALA A CB   1 
ATOM   531   H H    . ALA A 1 39  ? 101.212 114.155 125.805 1.00 31.47  ?  39  ALA A H    1 
ATOM   532   H HA   . ALA A 1 39  ? 101.922 116.584 124.958 1.00 31.47  ?  39  ALA A HA   1 
ATOM   533   H HB1  . ALA A 1 39  ? 100.016 117.318 126.101 1.00 31.47  ?  39  ALA A HB1  1 
ATOM   534   H HB2  . ALA A 1 39  ? 99.653  116.117 125.126 1.00 31.47  ?  39  ALA A HB2  1 
ATOM   535   H HB3  . ALA A 1 39  ? 99.809  115.855 126.685 1.00 31.47  ?  39  ALA A HB3  1 
ATOM   536   N N    . THR A 1 40  ? 103.092 115.705 127.663 1.00 30.70  ?  40  THR A N    1 
ATOM   537   C CA   . THR A 1 40  ? 103.830 116.070 128.865 1.00 30.70  ?  40  THR A CA   1 
ATOM   538   C C    . THR A 1 40  ? 105.325 115.984 128.592 1.00 30.70  ?  40  THR A C    1 
ATOM   539   O O    . THR A 1 40  ? 105.785 115.058 127.915 1.00 30.70  ?  40  THR A O    1 
ATOM   540   C CB   . THR A 1 40  ? 103.458 115.158 130.036 1.00 30.70  ?  40  THR A CB   1 
ATOM   541   O OG1  . THR A 1 40  ? 102.043 115.214 130.260 1.00 30.70  ?  40  THR A OG1  1 
ATOM   542   C CG2  . THR A 1 40  ? 104.186 115.588 131.302 1.00 30.70  ?  40  THR A CG2  1 
ATOM   543   H H    . THR A 1 40  ? 103.149 114.869 127.470 1.00 30.70  ?  40  THR A H    1 
ATOM   544   H HA   . THR A 1 40  ? 103.617 116.984 129.112 1.00 30.70  ?  40  THR A HA   1 
ATOM   545   H HB   . THR A 1 40  ? 103.716 114.246 129.829 1.00 30.70  ?  40  THR A HB   1 
ATOM   546   H HG1  . THR A 1 40  ? 101.634 114.945 129.578 1.00 30.70  ?  40  THR A HG1  1 
ATOM   547   H HG21 . THR A 1 40  ? 103.819 115.120 132.068 1.00 30.70  ?  40  THR A HG21 1 
ATOM   548   H HG22 . THR A 1 40  ? 104.081 116.543 131.436 1.00 30.70  ?  40  THR A HG22 1 
ATOM   549   H HG23 . THR A 1 40  ? 105.131 115.382 131.230 1.00 30.70  ?  40  THR A HG23 1 
ATOM   550   N N    . HIS A 1 41  ? 106.075 116.949 129.118 1.00 29.27  ?  41  HIS A N    1 
ATOM   551   C CA   . HIS A 1 41  ? 107.522 117.002 128.961 1.00 29.27  ?  41  HIS A CA   1 
ATOM   552   C C    . HIS A 1 41  ? 108.190 116.656 130.285 1.00 29.27  ?  41  HIS A C    1 
ATOM   553   O O    . HIS A 1 41  ? 107.798 117.169 131.338 1.00 29.27  ?  41  HIS A O    1 
ATOM   554   C CB   . HIS A 1 41  ? 107.966 118.387 128.488 1.00 29.27  ?  41  HIS A CB   1 
ATOM   555   C CG   . HIS A 1 41  ? 107.613 118.676 127.063 1.00 29.27  ?  41  HIS A CG   1 
ATOM   556   N ND1  . HIS A 1 41  ? 108.241 118.060 126.002 1.00 29.27  ?  41  HIS A ND1  1 
ATOM   557   C CD2  . HIS A 1 41  ? 106.691 119.507 126.523 1.00 29.27  ?  41  HIS A CD2  1 
ATOM   558   C CE1  . HIS A 1 41  ? 107.725 118.504 124.869 1.00 29.27  ?  41  HIS A CE1  1 
ATOM   559   N NE2  . HIS A 1 41  ? 106.782 119.382 125.158 1.00 29.27  ?  41  HIS A NE2  1 
ATOM   560   H H    . HIS A 1 41  ? 105.758 117.600 129.581 1.00 29.27  ?  41  HIS A H    1 
ATOM   561   H HA   . HIS A 1 41  ? 107.801 116.350 128.299 1.00 29.27  ?  41  HIS A HA   1 
ATOM   562   H HB2  . HIS A 1 41  ? 107.540 119.059 129.042 1.00 29.27  ?  41  HIS A HB2  1 
ATOM   563   H HB3  . HIS A 1 41  ? 108.930 118.452 128.574 1.00 29.27  ?  41  HIS A HB3  1 
ATOM   564   H HD2  . HIS A 1 41  ? 106.106 120.060 126.989 1.00 29.27  ?  41  HIS A HD2  1 
ATOM   565   H HE1  . HIS A 1 41  ? 107.981 118.241 124.015 1.00 29.27  ?  41  HIS A HE1  1 
ATOM   566   H HE2  . HIS A 1 41  ? 106.303 119.807 124.584 1.00 29.27  ?  41  HIS A HE2  1 
ATOM   567   N N    . ARG A 1 42  ? 109.196 115.788 130.226 1.00 25.90  ?  42  ARG A N    1 
ATOM   568   C CA   . ARG A 1 42  ? 109.903 115.305 131.405 1.00 25.90  ?  42  ARG A CA   1 
ATOM   569   C C    . ARG A 1 42  ? 111.278 115.954 131.472 1.00 25.90  ?  42  ARG A C    1 
ATOM   570   O O    . ARG A 1 42  ? 112.000 115.993 130.470 1.00 25.90  ?  42  ARG A O    1 
ATOM   571   C CB   . ARG A 1 42  ? 110.036 113.782 131.370 1.00 25.90  ?  42  ARG A CB   1 
ATOM   572   C CG   . ARG A 1 42  ? 108.727 113.047 131.603 1.00 25.90  ?  42  ARG A CG   1 
ATOM   573   C CD   . ARG A 1 42  ? 108.778 111.632 131.050 1.00 25.90  ?  42  ARG A CD   1 
ATOM   574   N NE   . ARG A 1 42  ? 108.812 111.620 129.589 1.00 25.90  ?  42  ARG A NE   1 
ATOM   575   C CZ   . ARG A 1 42  ? 107.788 111.954 128.810 1.00 25.90  ?  42  ARG A CZ   1 
ATOM   576   N NH1  . ARG A 1 42  ? 107.918 111.913 127.491 1.00 25.90  1  42  ARG A NH1  1 
ATOM   577   N NH2  . ARG A 1 42  ? 106.632 112.328 129.343 1.00 25.90  ?  42  ARG A NH2  1 
ATOM   578   H H    . ARG A 1 42  ? 109.495 115.455 129.491 1.00 25.90  ?  42  ARG A H    1 
ATOM   579   H HA   . ARG A 1 42  ? 109.408 115.550 132.202 1.00 25.90  ?  42  ARG A HA   1 
ATOM   580   H HB2  . ARG A 1 42  ? 110.375 113.518 130.501 1.00 25.90  ?  42  ARG A HB2  1 
ATOM   581   H HB3  . ARG A 1 42  ? 110.657 113.507 132.063 1.00 25.90  ?  42  ARG A HB3  1 
ATOM   582   H HG2  . ARG A 1 42  ? 108.555 112.994 132.556 1.00 25.90  ?  42  ARG A HG2  1 
ATOM   583   H HG3  . ARG A 1 42  ? 108.009 113.525 131.159 1.00 25.90  ?  42  ARG A HG3  1 
ATOM   584   H HD2  . ARG A 1 42  ? 109.579 111.192 131.375 1.00 25.90  ?  42  ARG A HD2  1 
ATOM   585   H HD3  . ARG A 1 42  ? 107.989 111.148 131.339 1.00 25.90  ?  42  ARG A HD3  1 
ATOM   586   H HE   . ARG A 1 42  ? 109.540 111.369 129.207 1.00 25.90  ?  42  ARG A HE   1 
ATOM   587   H HH11 . ARG A 1 42  ? 108.665 111.670 127.141 1.00 25.90  ?  42  ARG A HH11 1 
ATOM   588   H HH12 . ARG A 1 42  ? 107.256 112.127 126.987 1.00 25.90  ?  42  ARG A HH12 1 
ATOM   589   H HH21 . ARG A 1 42  ? 106.537 112.358 130.197 1.00 25.90  ?  42  ARG A HH21 1 
ATOM   590   H HH22 . ARG A 1 42  ? 105.974 112.542 128.832 1.00 25.90  ?  42  ARG A HH22 1 
ATOM   591   N N    . LEU A 1 43  ? 111.634 116.460 132.651 1.00 26.48  ?  43  LEU A N    1 
ATOM   592   C CA   . LEU A 1 43  ? 112.906 117.131 132.871 1.00 26.48  ?  43  LEU A CA   1 
ATOM   593   C C    . LEU A 1 43  ? 113.625 116.485 134.045 1.00 26.48  ?  43  LEU A C    1 
ATOM   594   O O    . LEU A 1 43  ? 112.988 116.019 134.995 1.00 26.48  ?  43  LEU A O    1 
ATOM   595   C CB   . LEU A 1 43  ? 112.708 118.628 133.145 1.00 26.48  ?  43  LEU A CB   1 
ATOM   596   C CG   . LEU A 1 43  ? 111.884 119.399 132.113 1.00 26.48  ?  43  LEU A CG   1 
ATOM   597   C CD1  . LEU A 1 43  ? 111.446 120.741 132.678 1.00 26.48  ?  43  LEU A CD1  1 
ATOM   598   C CD2  . LEU A 1 43  ? 112.673 119.587 130.827 1.00 26.48  ?  43  LEU A CD2  1 
ATOM   599   H H    . LEU A 1 43  ? 111.141 116.423 133.355 1.00 26.48  ?  43  LEU A H    1 
ATOM   600   H HA   . LEU A 1 43  ? 113.464 117.036 132.083 1.00 26.48  ?  43  LEU A HA   1 
ATOM   601   H HB2  . LEU A 1 43  ? 112.263 118.724 134.001 1.00 26.48  ?  43  LEU A HB2  1 
ATOM   602   H HB3  . LEU A 1 43  ? 113.582 119.047 133.188 1.00 26.48  ?  43  LEU A HB3  1 
ATOM   603   H HG   . LEU A 1 43  ? 111.086 118.890 131.901 1.00 26.48  ?  43  LEU A HG   1 
ATOM   604   H HD11 . LEU A 1 43  ? 110.900 120.589 133.465 1.00 26.48  ?  43  LEU A HD11 1 
ATOM   605   H HD12 . LEU A 1 43  ? 112.234 121.255 132.916 1.00 26.48  ?  43  LEU A HD12 1 
ATOM   606   H HD13 . LEU A 1 43  ? 110.932 121.214 132.005 1.00 26.48  ?  43  LEU A HD13 1 
ATOM   607   H HD21 . LEU A 1 43  ? 112.895 118.716 130.463 1.00 26.48  ?  43  LEU A HD21 1 
ATOM   608   H HD22 . LEU A 1 43  ? 112.130 120.082 130.194 1.00 26.48  ?  43  LEU A HD22 1 
ATOM   609   H HD23 . LEU A 1 43  ? 113.484 120.081 131.025 1.00 26.48  ?  43  LEU A HD23 1 
ATOM   610   N N    . LEU A 1 44  ? 114.952 116.460 133.974 1.00 22.29  ?  44  LEU A N    1 
ATOM   611   C CA   . LEU A 1 44  ? 115.789 115.915 135.035 1.00 22.29  ?  44  LEU A CA   1 
ATOM   612   C C    . LEU A 1 44  ? 116.569 117.045 135.692 1.00 22.29  ?  44  LEU A C    1 
ATOM   613   O O    . LEU A 1 44  ? 117.248 117.818 135.008 1.00 22.29  ?  44  LEU A O    1 
ATOM   614   C CB   . LEU A 1 44  ? 116.749 114.858 134.484 1.00 22.29  ?  44  LEU A CB   1 
ATOM   615   C CG   . LEU A 1 44  ? 117.858 114.383 135.428 1.00 22.29  ?  44  LEU A CG   1 
ATOM   616   C CD1  . LEU A 1 44  ? 117.269 113.680 136.641 1.00 22.29  ?  44  LEU A CD1  1 
ATOM   617   C CD2  . LEU A 1 44  ? 118.828 113.469 134.698 1.00 22.29  ?  44  LEU A CD2  1 
ATOM   618   H H    . LEU A 1 44  ? 115.401 116.761 133.305 1.00 22.29  ?  44  LEU A H    1 
ATOM   619   H HA   . LEU A 1 44  ? 115.229 115.498 135.708 1.00 22.29  ?  44  LEU A HA   1 
ATOM   620   H HB2  . LEU A 1 44  ? 116.229 114.077 134.236 1.00 22.29  ?  44  LEU A HB2  1 
ATOM   621   H HB3  . LEU A 1 44  ? 117.180 115.221 133.695 1.00 22.29  ?  44  LEU A HB3  1 
ATOM   622   H HG   . LEU A 1 44  ? 118.363 115.148 135.744 1.00 22.29  ?  44  LEU A HG   1 
ATOM   623   H HD11 . LEU A 1 44  ? 116.714 114.306 137.131 1.00 22.29  ?  44  LEU A HD11 1 
ATOM   624   H HD12 . LEU A 1 44  ? 117.993 113.367 137.206 1.00 22.29  ?  44  LEU A HD12 1 
ATOM   625   H HD13 . LEU A 1 44  ? 116.735 112.928 136.341 1.00 22.29  ?  44  LEU A HD13 1 
ATOM   626   H HD21 . LEU A 1 44  ? 119.308 113.986 134.033 1.00 22.29  ?  44  LEU A HD21 1 
ATOM   627   H HD22 . LEU A 1 44  ? 118.328 112.758 134.267 1.00 22.29  ?  44  LEU A HD22 1 
ATOM   628   H HD23 . LEU A 1 44  ? 119.452 113.095 135.339 1.00 22.29  ?  44  LEU A HD23 1 
ATOM   629   N N    . LEU A 1 45  ? 116.471 117.135 137.015 1.00 27.46  ?  45  LEU A N    1 
ATOM   630   C CA   . LEU A 1 45  ? 117.203 118.125 137.793 1.00 27.46  ?  45  LEU A CA   1 
ATOM   631   C C    . LEU A 1 45  ? 118.407 117.455 138.439 1.00 27.46  ?  45  LEU A C    1 
ATOM   632   O O    . LEU A 1 45  ? 118.264 116.435 139.122 1.00 27.46  ?  45  LEU A O    1 
ATOM   633   C CB   . LEU A 1 45  ? 116.306 118.752 138.862 1.00 27.46  ?  45  LEU A CB   1 
ATOM   634   C CG   . LEU A 1 45  ? 116.926 119.897 139.666 1.00 27.46  ?  45  LEU A CG   1 
ATOM   635   C CD1  . LEU A 1 45  ? 117.107 121.132 138.796 1.00 27.46  ?  45  LEU A CD1  1 
ATOM   636   C CD2  . LEU A 1 45  ? 116.072 120.216 140.880 1.00 27.46  ?  45  LEU A CD2  1 
ATOM   637   H H    . LEU A 1 45  ? 115.974 116.622 137.494 1.00 27.46  ?  45  LEU A H    1 
ATOM   638   H HA   . LEU A 1 45  ? 117.521 118.829 137.207 1.00 27.46  ?  45  LEU A HA   1 
ATOM   639   H HB2  . LEU A 1 45  ? 115.511 119.100 138.428 1.00 27.46  ?  45  LEU A HB2  1 
ATOM   640   H HB3  . LEU A 1 45  ? 116.052 118.060 139.492 1.00 27.46  ?  45  LEU A HB3  1 
ATOM   641   H HG   . LEU A 1 45  ? 117.801 119.625 139.982 1.00 27.46  ?  45  LEU A HG   1 
ATOM   642   H HD11 . LEU A 1 45  ? 117.743 120.933 138.092 1.00 27.46  ?  45  LEU A HD11 1 
ATOM   643   H HD12 . LEU A 1 45  ? 117.439 121.858 139.346 1.00 27.46  ?  45  LEU A HD12 1 
ATOM   644   H HD13 . LEU A 1 45  ? 116.250 121.375 138.411 1.00 27.46  ?  45  LEU A HD13 1 
ATOM   645   H HD21 . LEU A 1 45  ? 116.020 119.429 141.444 1.00 27.46  ?  45  LEU A HD21 1 
ATOM   646   H HD22 . LEU A 1 45  ? 115.184 120.470 140.583 1.00 27.46  ?  45  LEU A HD22 1 
ATOM   647   H HD23 . LEU A 1 45  ? 116.480 120.948 141.369 1.00 27.46  ?  45  LEU A HD23 1 
ATOM   648   N N    . LEU A 1 46  ? 119.588 118.029 138.223 1.00 25.25  ?  46  LEU A N    1 
ATOM   649   C CA   . LEU A 1 46  ? 120.829 117.446 138.708 1.00 25.25  ?  46  LEU A CA   1 
ATOM   650   C C    . LEU A 1 46  ? 121.740 118.554 139.216 1.00 25.25  ?  46  LEU A C    1 
ATOM   651   O O    . LEU A 1 46  ? 121.543 119.735 138.923 1.00 25.25  ?  46  LEU A O    1 
ATOM   652   C CB   . LEU A 1 46  ? 121.535 116.640 137.608 1.00 25.25  ?  46  LEU A CB   1 
ATOM   653   C CG   . LEU A 1 46  ? 122.497 115.541 138.066 1.00 25.25  ?  46  LEU A CG   1 
ATOM   654   C CD1  . LEU A 1 46  ? 121.767 114.457 138.844 1.00 25.25  ?  46  LEU A CD1  1 
ATOM   655   C CD2  . LEU A 1 46  ? 123.219 114.950 136.869 1.00 25.25  ?  46  LEU A CD2  1 
ATOM   656   H H    . LEU A 1 46  ? 119.695 118.765 137.792 1.00 25.25  ?  46  LEU A H    1 
ATOM   657   H HA   . LEU A 1 46  ? 120.635 116.852 139.449 1.00 25.25  ?  46  LEU A HA   1 
ATOM   658   H HB2  . LEU A 1 46  ? 120.856 116.216 137.061 1.00 25.25  ?  46  LEU A HB2  1 
ATOM   659   H HB3  . LEU A 1 46  ? 122.046 117.258 137.062 1.00 25.25  ?  46  LEU A HB3  1 
ATOM   660   H HG   . LEU A 1 46  ? 123.165 115.930 138.652 1.00 25.25  ?  46  LEU A HG   1 
ATOM   661   H HD11 . LEU A 1 46  ? 121.514 114.805 139.713 1.00 25.25  ?  46  LEU A HD11 1 
ATOM   662   H HD12 . LEU A 1 46  ? 120.975 114.192 138.350 1.00 25.25  ?  46  LEU A HD12 1 
ATOM   663   H HD13 . LEU A 1 46  ? 122.358 113.696 138.954 1.00 25.25  ?  46  LEU A HD13 1 
ATOM   664   H HD21 . LEU A 1 46  ? 123.612 115.672 136.357 1.00 25.25  ?  46  LEU A HD21 1 
ATOM   665   H HD22 . LEU A 1 46  ? 122.582 114.464 136.323 1.00 25.25  ?  46  LEU A HD22 1 
ATOM   666   H HD23 . LEU A 1 46  ? 123.913 114.348 137.183 1.00 25.25  ?  46  LEU A HD23 1 
ATOM   667   N N    . GLY A 1 47  ? 122.746 118.152 139.989 1.00 32.78  ?  47  GLY A N    1 
ATOM   668   C CA   . GLY A 1 47  ? 123.695 119.091 140.554 1.00 32.78  ?  47  GLY A CA   1 
ATOM   669   C C    . GLY A 1 47  ? 124.123 118.707 141.955 1.00 32.78  ?  47  GLY A C    1 
ATOM   670   O O    . GLY A 1 47  ? 123.463 117.896 142.613 1.00 32.78  ?  47  GLY A O    1 
ATOM   671   H H    . GLY A 1 47  ? 122.898 117.333 140.201 1.00 32.78  ?  47  GLY A H    1 
ATOM   672   H HA2  . GLY A 1 47  ? 124.484 119.129 139.992 1.00 32.78  ?  47  GLY A HA2  1 
ATOM   673   H HA3  . GLY A 1 47  ? 123.298 119.975 140.587 1.00 32.78  ?  47  GLY A HA3  1 
ATOM   674   N N    . ALA A 1 48  ? 125.226 119.283 142.424 1.00 42.50  ?  48  ALA A N    1 
ATOM   675   C CA   . ALA A 1 48  ? 125.726 118.965 143.753 1.00 42.50  ?  48  ALA A CA   1 
ATOM   676   C C    . ALA A 1 48  ? 124.764 119.472 144.821 1.00 42.50  ?  48  ALA A C    1 
ATOM   677   O O    . ALA A 1 48  ? 124.012 120.428 144.612 1.00 42.50  ?  48  ALA A O    1 
ATOM   678   C CB   . ALA A 1 48  ? 127.112 119.574 143.961 1.00 42.50  ?  48  ALA A CB   1 
ATOM   679   H H    . ALA A 1 48  ? 125.700 119.858 141.994 1.00 42.50  ?  48  ALA A H    1 
ATOM   680   H HA   . ALA A 1 48  ? 125.800 118.002 143.844 1.00 42.50  ?  48  ALA A HA   1 
ATOM   681   H HB1  . ALA A 1 48  ? 127.424 119.350 144.852 1.00 42.50  ?  48  ALA A HB1  1 
ATOM   682   H HB2  . ALA A 1 48  ? 127.051 120.537 143.864 1.00 42.50  ?  48  ALA A HB2  1 
ATOM   683   H HB3  . ALA A 1 48  ? 127.719 119.211 143.297 1.00 42.50  ?  48  ALA A HB3  1 
ATOM   684   N N    . GLY A 1 49  ? 124.794 118.815 145.982 1.00 45.90  ?  49  GLY A N    1 
ATOM   685   C CA   . GLY A 1 49  ? 123.922 119.200 147.077 1.00 45.90  ?  49  GLY A CA   1 
ATOM   686   C C    . GLY A 1 49  ? 124.146 120.612 147.574 1.00 45.90  ?  49  GLY A C    1 
ATOM   687   O O    . GLY A 1 49  ? 123.180 121.285 147.949 1.00 45.90  ?  49  GLY A O    1 
ATOM   688   H H    . GLY A 1 49  ? 125.310 118.149 146.155 1.00 45.90  ?  49  GLY A H    1 
ATOM   689   H HA2  . GLY A 1 49  ? 122.999 119.123 146.790 1.00 45.90  ?  49  GLY A HA2  1 
ATOM   690   H HA3  . GLY A 1 49  ? 124.059 118.593 147.821 1.00 45.90  ?  49  GLY A HA3  1 
ATOM   691   N N    . GLU A 1 50  ? 125.397 121.077 147.584 1.00 46.80  ?  50  GLU A N    1 
ATOM   692   C CA   . GLU A 1 50  ? 125.681 122.438 148.021 1.00 46.80  ?  50  GLU A CA   1 
ATOM   693   C C    . GLU A 1 50  ? 125.136 123.480 147.054 1.00 46.80  ?  50  GLU A C    1 
ATOM   694   O O    . GLU A 1 50  ? 125.025 124.654 147.425 1.00 46.80  ?  50  GLU A O    1 
ATOM   695   C CB   . GLU A 1 50  ? 127.190 122.628 148.192 1.00 46.80  ?  50  GLU A CB   1 
ATOM   696   C CG   . GLU A 1 50  ? 127.602 123.918 148.899 1.00 46.80  ?  50  GLU A CG   1 
ATOM   697   C CD   . GLU A 1 50  ? 126.960 124.085 150.265 1.00 46.80  ?  50  GLU A CD   1 
ATOM   698   O OE1  . GLU A 1 50  ? 125.736 124.323 150.329 1.00 46.80  ?  50  GLU A OE1  1 
ATOM   699   O OE2  . GLU A 1 50  ? 127.684 123.978 151.278 1.00 46.80  -1 50  GLU A OE2  1 
ATOM   700   H H    . GLU A 1 50  ? 126.089 120.628 147.343 1.00 46.80  ?  50  GLU A H    1 
ATOM   701   H HA   . GLU A 1 50  ? 125.255 122.576 148.879 1.00 46.80  ?  50  GLU A HA   1 
ATOM   702   H HB2  . GLU A 1 50  ? 127.538 121.886 148.711 1.00 46.80  ?  50  GLU A HB2  1 
ATOM   703   H HB3  . GLU A 1 50  ? 127.602 122.632 147.313 1.00 46.80  ?  50  GLU A HB3  1 
ATOM   704   H HG2  . GLU A 1 50  ? 128.565 123.916 149.021 1.00 46.80  ?  50  GLU A HG2  1 
ATOM   705   H HG3  . GLU A 1 50  ? 127.340 124.675 148.352 1.00 46.80  ?  50  GLU A HG3  1 
ATOM   706   N N    . SER A 1 51  ? 124.793 123.083 145.832 1.00 40.84  ?  51  SER A N    1 
ATOM   707   C CA   . SER A 1 51  ? 124.256 124.023 144.860 1.00 40.84  ?  51  SER A CA   1 
ATOM   708   C C    . SER A 1 51  ? 122.849 124.455 145.255 1.00 40.84  ?  51  SER A C    1 
ATOM   709   O O    . SER A 1 51  ? 122.196 123.836 146.101 1.00 40.84  ?  51  SER A O    1 
ATOM   710   C CB   . SER A 1 51  ? 124.239 123.397 143.466 1.00 40.84  ?  51  SER A CB   1 
ATOM   711   O OG   . SER A 1 51  ? 124.109 124.390 142.464 1.00 40.84  ?  51  SER A OG   1 
ATOM   712   H H    . SER A 1 51  ? 124.862 122.276 145.542 1.00 40.84  ?  51  SER A H    1 
ATOM   713   H HA   . SER A 1 51  ? 124.820 124.812 144.833 1.00 40.84  ?  51  SER A HA   1 
ATOM   714   H HB2  . SER A 1 51  ? 125.070 122.916 143.327 1.00 40.84  ?  51  SER A HB2  1 
ATOM   715   H HB3  . SER A 1 51  ? 123.488 122.786 143.404 1.00 40.84  ?  51  SER A HB3  1 
ATOM   716   H HG   . SER A 1 51  ? 124.130 124.034 141.704 1.00 40.84  ?  51  SER A HG   1 
ATOM   717   N N    . GLY A 1 52  ? 122.382 125.532 144.629 1.00 40.01  ?  52  GLY A N    1 
ATOM   718   C CA   . GLY A 1 52  ? 121.076 126.079 144.937 1.00 40.01  ?  52  GLY A CA   1 
ATOM   719   C C    . GLY A 1 52  ? 119.936 125.377 144.226 1.00 40.01  ?  52  GLY A C    1 
ATOM   720   O O    . GLY A 1 52  ? 118.863 125.960 144.044 1.00 40.01  ?  52  GLY A O    1 
ATOM   721   H H    . GLY A 1 52  ? 122.809 125.963 144.020 1.00 40.01  ?  52  GLY A H    1 
ATOM   722   H HA2  . GLY A 1 52  ? 120.921 126.015 145.893 1.00 40.01  ?  52  GLY A HA2  1 
ATOM   723   H HA3  . GLY A 1 52  ? 121.056 127.016 144.689 1.00 40.01  ?  52  GLY A HA3  1 
ATOM   724   N N    . LYS A 1 53  ? 120.152 124.124 143.820 1.00 36.99  ?  53  LYS A N    1 
ATOM   725   C CA   . LYS A 1 53  ? 119.096 123.381 143.141 1.00 36.99  ?  53  LYS A CA   1 
ATOM   726   C C    . LYS A 1 53  ? 117.879 123.197 144.038 1.00 36.99  ?  53  LYS A C    1 
ATOM   727   O O    . LYS A 1 53  ? 116.741 123.257 143.559 1.00 36.99  ?  53  LYS A O    1 
ATOM   728   C CB   . LYS A 1 53  ? 119.623 122.023 142.674 1.00 36.99  ?  53  LYS A CB   1 
ATOM   729   C CG   . LYS A 1 53  ? 120.140 121.130 143.794 1.00 36.99  ?  53  LYS A CG   1 
ATOM   730   C CD   . LYS A 1 53  ? 120.629 119.789 143.263 1.00 36.99  ?  53  LYS A CD   1 
ATOM   731   C CE   . LYS A 1 53  ? 119.473 118.864 142.910 1.00 36.99  ?  53  LYS A CE   1 
ATOM   732   N NZ   . LYS A 1 53  ? 118.895 118.206 144.114 1.00 36.99  1  53  LYS A NZ   1 
ATOM   733   H H    . LYS A 1 53  ? 120.886 123.689 143.920 1.00 36.99  ?  53  LYS A H    1 
ATOM   734   H HA   . LYS A 1 53  ? 118.816 123.878 142.357 1.00 36.99  ?  53  LYS A HA   1 
ATOM   735   H HB2  . LYS A 1 53  ? 118.904 121.552 142.225 1.00 36.99  ?  53  LYS A HB2  1 
ATOM   736   H HB3  . LYS A 1 53  ? 120.354 122.171 142.054 1.00 36.99  ?  53  LYS A HB3  1 
ATOM   737   H HG2  . LYS A 1 53  ? 120.883 121.570 144.237 1.00 36.99  ?  53  LYS A HG2  1 
ATOM   738   H HG3  . LYS A 1 53  ? 119.425 120.960 144.426 1.00 36.99  ?  53  LYS A HG3  1 
ATOM   739   H HD2  . LYS A 1 53  ? 121.155 119.936 142.462 1.00 36.99  ?  53  LYS A HD2  1 
ATOM   740   H HD3  . LYS A 1 53  ? 121.168 119.355 143.942 1.00 36.99  ?  53  LYS A HD3  1 
ATOM   741   H HE2  . LYS A 1 53  ? 118.770 119.374 142.479 1.00 36.99  ?  53  LYS A HE2  1 
ATOM   742   H HE3  . LYS A 1 53  ? 119.794 118.170 142.313 1.00 36.99  ?  53  LYS A HE3  1 
ATOM   743   H HZ1  . LYS A 1 53  ? 118.224 117.672 143.876 1.00 36.99  ?  53  LYS A HZ1  1 
ATOM   744   H HZ2  . LYS A 1 53  ? 119.518 117.722 144.525 1.00 36.99  ?  53  LYS A HZ2  1 
ATOM   745   H HZ3  . LYS A 1 53  ? 118.587 118.822 144.678 1.00 36.99  ?  53  LYS A HZ3  1 
ATOM   746   N N    . ASN A 1 54  ? 118.094 122.973 145.336 1.00 42.21  ?  54  ASN A N    1 
ATOM   747   C CA   . ASN A 1 54  ? 116.971 122.809 146.252 1.00 42.21  ?  54  ASN A CA   1 
ATOM   748   C C    . ASN A 1 54  ? 116.116 124.068 146.322 1.00 42.21  ?  54  ASN A C    1 
ATOM   749   O O    . ASN A 1 54  ? 114.883 123.977 146.347 1.00 42.21  ?  54  ASN A O    1 
ATOM   750   C CB   . ASN A 1 54  ? 117.480 122.439 147.645 1.00 42.21  ?  54  ASN A CB   1 
ATOM   751   C CG   . ASN A 1 54  ? 117.791 120.962 147.778 1.00 42.21  ?  54  ASN A CG   1 
ATOM   752   O OD1  . ASN A 1 54  ? 116.888 120.124 147.786 1.00 42.21  ?  54  ASN A OD1  1 
ATOM   753   N ND2  . ASN A 1 54  ? 119.073 120.633 147.883 1.00 42.21  ?  54  ASN A ND2  1 
ATOM   754   H H    . ASN A 1 54  ? 118.869 122.913 145.704 1.00 42.21  ?  54  ASN A H    1 
ATOM   755   H HA   . ASN A 1 54  ? 116.410 122.084 145.936 1.00 42.21  ?  54  ASN A HA   1 
ATOM   756   H HB2  . ASN A 1 54  ? 118.294 122.935 147.826 1.00 42.21  ?  54  ASN A HB2  1 
ATOM   757   H HB3  . ASN A 1 54  ? 116.802 122.664 148.300 1.00 42.21  ?  54  ASN A HB3  1 
ATOM   758   H HD21 . ASN A 1 54  ? 119.676 121.246 147.873 1.00 42.21  ?  54  ASN A HD21 1 
ATOM   759   H HD22 . ASN A 1 54  ? 119.300 119.807 147.960 1.00 42.21  ?  54  ASN A HD22 1 
ATOM   760   N N    . THR A 1 55  ? 116.745 125.245 146.355 1.00 43.01  ?  55  THR A N    1 
ATOM   761   C CA   . THR A 1 55  ? 115.980 126.487 146.389 1.00 43.01  ?  55  THR A CA   1 
ATOM   762   C C    . THR A 1 55  ? 115.176 126.673 145.108 1.00 43.01  ?  55  THR A C    1 
ATOM   763   O O    . THR A 1 55  ? 114.065 127.214 145.139 1.00 43.01  ?  55  THR A O    1 
ATOM   764   C CB   . THR A 1 55  ? 116.917 127.676 146.608 1.00 43.01  ?  55  THR A CB   1 
ATOM   765   O OG1  . THR A 1 55  ? 117.576 127.542 147.873 1.00 43.01  ?  55  THR A OG1  1 
ATOM   766   C CG2  . THR A 1 55  ? 116.137 128.984 146.583 1.00 43.01  ?  55  THR A CG2  1 
ATOM   767   H H    . THR A 1 55  ? 117.599 125.348 146.358 1.00 43.01  ?  55  THR A H    1 
ATOM   768   H HA   . THR A 1 55  ? 115.358 126.455 147.131 1.00 43.01  ?  55  THR A HA   1 
ATOM   769   H HB   . THR A 1 55  ? 117.579 127.700 145.899 1.00 43.01  ?  55  THR A HB   1 
ATOM   770   H HG1  . THR A 1 55  ? 118.023 126.832 147.890 1.00 43.01  ?  55  THR A HG1  1 
ATOM   771   H HG21 . THR A 1 55  ? 116.678 129.697 146.959 1.00 43.01  ?  55  THR A HG21 1 
ATOM   772   H HG22 . THR A 1 55  ? 115.902 129.217 145.672 1.00 43.01  ?  55  THR A HG22 1 
ATOM   773   H HG23 . THR A 1 55  ? 115.326 128.896 147.108 1.00 43.01  ?  55  THR A HG23 1 
ATOM   774   N N    . ILE A 1 56  ? 115.723 126.236 143.972 1.00 39.46  ?  56  ILE A N    1 
ATOM   775   C CA   . ILE A 1 56  ? 115.001 126.346 142.706 1.00 39.46  ?  56  ILE A CA   1 
ATOM   776   C C    . ILE A 1 56  ? 113.721 125.520 142.756 1.00 39.46  ?  56  ILE A C    1 
ATOM   777   O O    . ILE A 1 56  ? 112.658 125.958 142.298 1.00 39.46  ?  56  ILE A O    1 
ATOM   778   C CB   . ILE A 1 56  ? 115.905 125.919 141.536 1.00 39.46  ?  56  ILE A CB   1 
ATOM   779   C CG1  . ILE A 1 56  ? 117.098 126.871 141.411 1.00 39.46  ?  56  ILE A CG1  1 
ATOM   780   C CG2  . ILE A 1 56  ? 115.108 125.871 140.241 1.00 39.46  ?  56  ILE A CG2  1 
ATOM   781   C CD1  . ILE A 1 56  ? 118.184 126.379 140.477 1.00 39.46  ?  56  ILE A CD1  1 
ATOM   782   H H    . ILE A 1 56  ? 116.502 125.877 143.908 1.00 39.46  ?  56  ILE A H    1 
ATOM   783   H HA   . ILE A 1 56  ? 114.752 127.273 142.566 1.00 39.46  ?  56  ILE A HA   1 
ATOM   784   H HB   . ILE A 1 56  ? 116.243 125.028 141.720 1.00 39.46  ?  56  ILE A HB   1 
ATOM   785   H HG12 . ILE A 1 56  ? 116.782 127.724 141.073 1.00 39.46  ?  56  ILE A HG12 1 
ATOM   786   H HG13 . ILE A 1 56  ? 117.496 126.993 142.287 1.00 39.46  ?  56  ILE A HG13 1 
ATOM   787   H HG21 . ILE A 1 56  ? 114.597 125.047 140.219 1.00 39.46  ?  56  ILE A HG21 1 
ATOM   788   H HG22 . ILE A 1 56  ? 115.718 125.897 139.487 1.00 39.46  ?  56  ILE A HG22 1 
ATOM   789   H HG23 . ILE A 1 56  ? 114.512 126.635 140.208 1.00 39.46  ?  56  ILE A HG23 1 
ATOM   790   H HD11 . ILE A 1 56  ? 118.981 126.916 140.609 1.00 39.46  ?  56  ILE A HD11 1 
ATOM   791   H HD12 . ILE A 1 56  ? 118.375 125.449 140.678 1.00 39.46  ?  56  ILE A HD12 1 
ATOM   792   H HD13 . ILE A 1 56  ? 117.877 126.462 139.561 1.00 39.46  ?  56  ILE A HD13 1 
ATOM   793   N N    . VAL A 1 57  ? 113.807 124.307 143.307 1.00 40.79  ?  57  VAL A N    1 
ATOM   794   C CA   . VAL A 1 57  ? 112.626 123.456 143.414 1.00 40.79  ?  57  VAL A CA   1 
ATOM   795   C C    . VAL A 1 57  ? 111.574 124.117 144.294 1.00 40.79  ?  57  VAL A C    1 
ATOM   796   O O    . VAL A 1 57  ? 110.383 124.130 143.960 1.00 40.79  ?  57  VAL A O    1 
ATOM   797   C CB   . VAL A 1 57  ? 113.015 122.066 143.951 1.00 40.79  ?  57  VAL A CB   1 
ATOM   798   C CG1  . VAL A 1 57  ? 111.773 121.212 144.165 1.00 40.79  ?  57  VAL A CG1  1 
ATOM   799   C CG2  . VAL A 1 57  ? 113.978 121.379 142.998 1.00 40.79  ?  57  VAL A CG2  1 
ATOM   800   H H    . VAL A 1 57  ? 114.528 123.960 143.622 1.00 40.79  ?  57  VAL A H    1 
ATOM   801   H HA   . VAL A 1 57  ? 112.243 123.338 142.531 1.00 40.79  ?  57  VAL A HA   1 
ATOM   802   H HB   . VAL A 1 57  ? 113.460 122.169 144.806 1.00 40.79  ?  57  VAL A HB   1 
ATOM   803   H HG11 . VAL A 1 57  ? 112.039 120.281 144.221 1.00 40.79  ?  57  VAL A HG11 1 
ATOM   804   H HG12 . VAL A 1 57  ? 111.340 121.482 144.989 1.00 40.79  ?  57  VAL A HG12 1 
ATOM   805   H HG13 . VAL A 1 57  ? 111.171 121.338 143.414 1.00 40.79  ?  57  VAL A HG13 1 
ATOM   806   H HG21 . VAL A 1 57  ? 114.196 120.501 143.350 1.00 40.79  ?  57  VAL A HG21 1 
ATOM   807   H HG22 . VAL A 1 57  ? 113.554 121.291 142.130 1.00 40.79  ?  57  VAL A HG22 1 
ATOM   808   H HG23 . VAL A 1 57  ? 114.783 121.913 142.921 1.00 40.79  ?  57  VAL A HG23 1 
ATOM   809   N N    . LYS A 1 58  ? 111.993 124.673 145.432 1.00 47.22  ?  58  LYS A N    1 
ATOM   810   C CA   . LYS A 1 58  ? 111.044 125.330 146.325 1.00 47.22  ?  58  LYS A CA   1 
ATOM   811   C C    . LYS A 1 58  ? 110.389 126.523 145.640 1.00 47.22  ?  58  LYS A C    1 
ATOM   812   O O    . LYS A 1 58  ? 109.175 126.729 145.750 1.00 47.22  ?  58  LYS A O    1 
ATOM   813   C CB   . LYS A 1 58  ? 111.753 125.767 147.609 1.00 47.22  ?  58  LYS A CB   1 
ATOM   814   C CG   . LYS A 1 58  ? 110.831 126.228 148.741 1.00 47.22  ?  58  LYS A CG   1 
ATOM   815   C CD   . LYS A 1 58  ? 109.667 125.276 148.992 1.00 47.22  ?  58  LYS A CD   1 
ATOM   816   C CE   . LYS A 1 58  ? 110.145 123.847 149.205 1.00 47.22  ?  58  LYS A CE   1 
ATOM   817   N NZ   . LYS A 1 58  ? 109.212 123.069 150.066 1.00 47.22  1  58  LYS A NZ   1 
ATOM   818   H H    . LYS A 1 58  ? 112.808 124.683 145.706 1.00 47.22  ?  58  LYS A H    1 
ATOM   819   H HA   . LYS A 1 58  ? 110.348 124.696 146.549 1.00 47.22  ?  58  LYS A HA   1 
ATOM   820   H HB2  . LYS A 1 58  ? 112.277 125.022 147.941 1.00 47.22  ?  58  LYS A HB2  1 
ATOM   821   H HB3  . LYS A 1 58  ? 112.343 126.508 147.396 1.00 47.22  ?  58  LYS A HB3  1 
ATOM   822   H HG2  . LYS A 1 58  ? 111.347 126.291 149.560 1.00 47.22  ?  58  LYS A HG2  1 
ATOM   823   H HG3  . LYS A 1 58  ? 110.463 127.096 148.513 1.00 47.22  ?  58  LYS A HG3  1 
ATOM   824   H HD2  . LYS A 1 58  ? 109.196 125.557 149.792 1.00 47.22  ?  58  LYS A HD2  1 
ATOM   825   H HD3  . LYS A 1 58  ? 109.065 125.289 148.231 1.00 47.22  ?  58  LYS A HD3  1 
ATOM   826   H HE2  . LYS A 1 58  ? 110.207 123.398 148.348 1.00 47.22  ?  58  LYS A HE2  1 
ATOM   827   H HE3  . LYS A 1 58  ? 111.013 123.863 149.637 1.00 47.22  ?  58  LYS A HE3  1 
ATOM   828   H HZ1  . LYS A 1 58  ? 109.518 122.241 150.174 1.00 47.22  ?  58  LYS A HZ1  1 
ATOM   829   H HZ2  . LYS A 1 58  ? 109.141 123.457 150.864 1.00 47.22  ?  58  LYS A HZ2  1 
ATOM   830   H HZ3  . LYS A 1 58  ? 108.407 123.034 149.688 1.00 47.22  ?  58  LYS A HZ3  1 
ATOM   831   N N    . GLN A 1 59  ? 111.183 127.323 144.924 1.00 47.37  ?  59  GLN A N    1 
ATOM   832   C CA   . GLN A 1 59  ? 110.630 128.482 144.232 1.00 47.37  ?  59  GLN A CA   1 
ATOM   833   C C    . GLN A 1 59  ? 109.629 128.070 143.161 1.00 47.37  ?  59  GLN A C    1 
ATOM   834   O O    . GLN A 1 59  ? 108.567 128.689 143.035 1.00 47.37  ?  59  GLN A O    1 
ATOM   835   C CB   . GLN A 1 59  ? 111.759 129.307 143.606 1.00 47.37  ?  59  GLN A CB   1 
ATOM   836   C CG   . GLN A 1 59  ? 112.396 130.355 144.522 1.00 47.37  ?  59  GLN A CG   1 
ATOM   837   C CD   . GLN A 1 59  ? 111.382 131.195 145.279 1.00 47.37  ?  59  GLN A CD   1 
ATOM   838   O OE1  . GLN A 1 59  ? 110.274 131.435 144.799 1.00 47.37  ?  59  GLN A OE1  1 
ATOM   839   N NE2  . GLN A 1 59  ? 111.760 131.646 146.469 1.00 47.37  ?  59  GLN A NE2  1 
ATOM   840   H H    . GLN A 1 59  ? 112.030 127.217 144.826 1.00 47.37  ?  59  GLN A H    1 
ATOM   841   H HA   . GLN A 1 59  ? 110.155 129.026 144.875 1.00 47.37  ?  59  GLN A HA   1 
ATOM   842   H HB2  . GLN A 1 59  ? 112.462 128.701 143.324 1.00 47.37  ?  59  GLN A HB2  1 
ATOM   843   H HB3  . GLN A 1 59  ? 111.405 129.774 142.833 1.00 47.37  ?  59  GLN A HB3  1 
ATOM   844   H HG2  . GLN A 1 59  ? 112.954 129.904 145.174 1.00 47.37  ?  59  GLN A HG2  1 
ATOM   845   H HG3  . GLN A 1 59  ? 112.936 130.955 143.984 1.00 47.37  ?  59  GLN A HG3  1 
ATOM   846   H HE21 . GLN A 1 59  ? 112.543 131.458 146.772 1.00 47.37  ?  59  GLN A HE21 1 
ATOM   847   H HE22 . GLN A 1 59  ? 111.222 132.127 146.937 1.00 47.37  ?  59  GLN A HE22 1 
ATOM   848   N N    . MET A 1 60  ? 109.945 127.033 142.383 1.00 42.11  ?  60  MET A N    1 
ATOM   849   C CA   . MET A 1 60  ? 109.038 126.600 141.326 1.00 42.11  ?  60  MET A CA   1 
ATOM   850   C C    . MET A 1 60  ? 107.785 125.935 141.881 1.00 42.11  ?  60  MET A C    1 
ATOM   851   O O    . MET A 1 60  ? 106.717 126.028 141.265 1.00 42.11  ?  60  MET A O    1 
ATOM   852   C CB   . MET A 1 60  ? 109.763 125.653 140.370 1.00 42.11  ?  60  MET A CB   1 
ATOM   853   C CG   . MET A 1 60  ? 110.826 126.342 139.529 1.00 42.11  ?  60  MET A CG   1 
ATOM   854   S SD   . MET A 1 60  ? 112.121 125.230 138.956 1.00 42.11  ?  60  MET A SD   1 
ATOM   855   C CE   . MET A 1 60  ? 112.324 125.785 137.266 1.00 42.11  ?  60  MET A CE   1 
ATOM   856   H H    . MET A 1 60  ? 110.668 126.571 142.446 1.00 42.11  ?  60  MET A H    1 
ATOM   857   H HA   . MET A 1 60  ? 108.770 127.380 140.814 1.00 42.11  ?  60  MET A HA   1 
ATOM   858   H HB2  . MET A 1 60  ? 110.198 124.957 140.888 1.00 42.11  ?  60  MET A HB2  1 
ATOM   859   H HB3  . MET A 1 60  ? 109.114 125.258 139.766 1.00 42.11  ?  60  MET A HB3  1 
ATOM   860   H HG2  . MET A 1 60  ? 110.403 126.731 138.749 1.00 42.11  ?  60  MET A HG2  1 
ATOM   861   H HG3  . MET A 1 60  ? 111.245 127.038 140.059 1.00 42.11  ?  60  MET A HG3  1 
ATOM   862   H HE1  . MET A 1 60  ? 113.016 125.255 136.841 1.00 42.11  ?  60  MET A HE1  1 
ATOM   863   H HE2  . MET A 1 60  ? 111.484 125.673 136.794 1.00 42.11  ?  60  MET A HE2  1 
ATOM   864   H HE3  . MET A 1 60  ? 112.579 126.721 137.270 1.00 42.11  ?  60  MET A HE3  1 
ATOM   865   N N    . ARG A 1 61  ? 107.888 125.264 143.030 1.00 46.64  ?  61  ARG A N    1 
ATOM   866   C CA   . ARG A 1 61  ? 106.709 124.667 143.647 1.00 46.64  ?  61  ARG A CA   1 
ATOM   867   C C    . ARG A 1 61  ? 105.758 125.723 144.194 1.00 46.64  ?  61  ARG A C    1 
ATOM   868   O O    . ARG A 1 61  ? 104.544 125.494 144.236 1.00 46.64  ?  61  ARG A O    1 
ATOM   869   C CB   . ARG A 1 61  ? 107.127 123.713 144.767 1.00 46.64  ?  61  ARG A CB   1 
ATOM   870   C CG   . ARG A 1 61  ? 107.751 122.416 144.278 1.00 46.64  ?  61  ARG A CG   1 
ATOM   871   C CD   . ARG A 1 61  ? 108.217 121.555 145.440 1.00 46.64  ?  61  ARG A CD   1 
ATOM   872   N NE   . ARG A 1 61  ? 107.099 120.979 146.182 1.00 46.64  ?  61  ARG A NE   1 
ATOM   873   C CZ   . ARG A 1 61  ? 107.231 120.129 147.196 1.00 46.64  ?  61  ARG A CZ   1 
ATOM   874   N NH1  . ARG A 1 61  ? 106.154 119.658 147.810 1.00 46.64  1  61  ARG A NH1  1 
ATOM   875   N NH2  . ARG A 1 61  ? 108.436 119.749 147.598 1.00 46.64  ?  61  ARG A NH2  1 
ATOM   876   H H    . ARG A 1 61  ? 108.620 125.143 143.465 1.00 46.64  ?  61  ARG A H    1 
ATOM   877   H HA   . ARG A 1 61  ? 106.231 124.153 142.978 1.00 46.64  ?  61  ARG A HA   1 
ATOM   878   H HB2  . ARG A 1 61  ? 107.777 124.160 145.330 1.00 46.64  ?  61  ARG A HB2  1 
ATOM   879   H HB3  . ARG A 1 61  ? 106.342 123.484 145.290 1.00 46.64  ?  61  ARG A HB3  1 
ATOM   880   H HG2  . ARG A 1 61  ? 107.092 121.914 143.774 1.00 46.64  ?  61  ARG A HG2  1 
ATOM   881   H HG3  . ARG A 1 61  ? 108.518 122.617 143.720 1.00 46.64  ?  61  ARG A HG3  1 
ATOM   882   H HD2  . ARG A 1 61  ? 108.760 120.827 145.099 1.00 46.64  ?  61  ARG A HD2  1 
ATOM   883   H HD3  . ARG A 1 61  ? 108.737 122.100 146.052 1.00 46.64  ?  61  ARG A HD3  1 
ATOM   884   H HE   . ARG A 1 61  ? 106.303 121.201 145.944 1.00 46.64  ?  61  ARG A HE   1 
ATOM   885   H HH11 . ARG A 1 61  ? 105.371 119.902 147.553 1.00 46.64  ?  61  ARG A HH11 1 
ATOM   886   H HH12 . ARG A 1 61  ? 106.240 119.109 148.466 1.00 46.64  ?  61  ARG A HH12 1 
ATOM   887   H HH21 . ARG A 1 61  ? 109.139 120.050 147.205 1.00 46.64  ?  61  ARG A HH21 1 
ATOM   888   H HH22 . ARG A 1 61  ? 108.515 119.199 148.255 1.00 46.64  ?  61  ARG A HH22 1 
ATOM   889   N N    . ILE A 1 62  ? 106.281 126.870 144.615 1.00 49.00  ?  62  ILE A N    1 
ATOM   890   C CA   . ILE A 1 62  ? 105.451 127.944 145.144 1.00 49.00  ?  62  ILE A CA   1 
ATOM   891   C C    . ILE A 1 62  ? 104.514 128.452 144.055 1.00 49.00  ?  62  ILE A C    1 
ATOM   892   O O    . ILE A 1 62  ? 104.869 128.474 142.877 1.00 49.00  ?  62  ILE A O    1 
ATOM   893   C CB   . ILE A 1 62  ? 106.317 129.088 145.704 1.00 49.00  ?  62  ILE A CB   1 
ATOM   894   C CG1  . ILE A 1 62  ? 106.961 128.666 147.025 1.00 49.00  ?  62  ILE A CG1  1 
ATOM   895   C CG2  . ILE A 1 62  ? 105.479 130.345 145.901 1.00 49.00  ?  62  ILE A CG2  1 
ATOM   896   C CD1  . ILE A 1 62  ? 108.150 129.515 147.425 1.00 49.00  ?  62  ILE A CD1  1 
ATOM   897   H H    . ILE A 1 62  ? 107.122 127.051 144.605 1.00 49.00  ?  62  ILE A H    1 
ATOM   898   H HA   . ILE A 1 62  ? 104.909 127.597 145.869 1.00 49.00  ?  62  ILE A HA   1 
ATOM   899   H HB   . ILE A 1 62  ? 107.020 129.283 145.065 1.00 49.00  ?  62  ILE A HB   1 
ATOM   900   H HG12 . ILE A 1 62  ? 106.299 128.733 147.731 1.00 49.00  ?  62  ILE A HG12 1 
ATOM   901   H HG13 . ILE A 1 62  ? 107.265 127.748 146.946 1.00 49.00  ?  62  ILE A HG13 1 
ATOM   902   H HG21 . ILE A 1 62  ? 105.359 130.785 145.045 1.00 49.00  ?  62  ILE A HG21 1 
ATOM   903   H HG22 . ILE A 1 62  ? 104.618 130.097 146.271 1.00 49.00  ?  62  ILE A HG22 1 
ATOM   904   H HG23 . ILE A 1 62  ? 105.942 130.940 146.511 1.00 49.00  ?  62  ILE A HG23 1 
ATOM   905   H HD11 . ILE A 1 62  ? 108.551 129.138 148.224 1.00 49.00  ?  62  ILE A HD11 1 
ATOM   906   H HD12 . ILE A 1 62  ? 108.794 129.516 146.700 1.00 49.00  ?  62  ILE A HD12 1 
ATOM   907   H HD13 . ILE A 1 62  ? 107.849 130.420 147.601 1.00 49.00  ?  62  ILE A HD13 1 
ATOM   908   N N    . THR A 1 204 ? 112.264 110.167 152.051 1.00 27.83  ?  204 THR A N    1 
ATOM   909   C CA   . THR A 1 204 ? 113.140 109.002 152.015 1.00 27.83  ?  204 THR A CA   1 
ATOM   910   C C    . THR A 1 204 ? 113.075 108.312 150.653 1.00 27.83  ?  204 THR A C    1 
ATOM   911   O O    . THR A 1 204 ? 113.869 107.417 150.363 1.00 27.83  ?  204 THR A O    1 
ATOM   912   C CB   . THR A 1 204 ? 112.770 107.987 153.115 1.00 27.83  ?  204 THR A CB   1 
ATOM   913   O OG1  . THR A 1 204 ? 112.628 108.666 154.369 1.00 27.83  ?  204 THR A OG1  1 
ATOM   914   C CG2  . THR A 1 204 ? 113.845 106.916 153.244 1.00 27.83  ?  204 THR A CG2  1 
ATOM   915   H H    . THR A 1 204 ? 111.432 109.983 151.938 1.00 27.83  ?  204 THR A H    1 
ATOM   916   H HA   . THR A 1 204 ? 114.054 109.288 152.164 1.00 27.83  ?  204 THR A HA   1 
ATOM   917   H HB   . THR A 1 204 ? 111.933 107.554 152.886 1.00 27.83  ?  204 THR A HB   1 
ATOM   918   H HG1  . THR A 1 204 ? 112.003 109.226 154.323 1.00 27.83  ?  204 THR A HG1  1 
ATOM   919   H HG21 . THR A 1 204 ? 113.725 106.427 154.073 1.00 27.83  ?  204 THR A HG21 1 
ATOM   920   H HG22 . THR A 1 204 ? 113.788 106.295 152.501 1.00 27.83  ?  204 THR A HG22 1 
ATOM   921   H HG23 . THR A 1 204 ? 114.724 107.327 153.246 1.00 27.83  ?  204 THR A HG23 1 
ATOM   922   N N    . SER A 1 205 ? 112.130 108.737 149.818 1.00 25.79  ?  205 SER A N    1 
ATOM   923   C CA   . SER A 1 205 ? 111.987 108.152 148.494 1.00 25.79  ?  205 SER A CA   1 
ATOM   924   C C    . SER A 1 205 ? 113.214 108.451 147.641 1.00 25.79  ?  205 SER A C    1 
ATOM   925   O O    . SER A 1 205 ? 113.916 109.446 147.845 1.00 25.79  ?  205 SER A O    1 
ATOM   926   C CB   . SER A 1 205 ? 110.730 108.686 147.808 1.00 25.79  ?  205 SER A CB   1 
ATOM   927   O OG   . SER A 1 205 ? 110.763 110.099 147.709 1.00 25.79  ?  205 SER A OG   1 
ATOM   928   H H    . SER A 1 205 ? 111.562 109.358 149.991 1.00 25.79  ?  205 SER A H    1 
ATOM   929   H HA   . SER A 1 205 ? 111.902 107.189 148.577 1.00 25.79  ?  205 SER A HA   1 
ATOM   930   H HB2  . SER A 1 205 ? 110.674 108.309 146.916 1.00 25.79  ?  205 SER A HB2  1 
ATOM   931   H HB3  . SER A 1 205 ? 109.953 108.424 148.326 1.00 25.79  ?  205 SER A HB3  1 
ATOM   932   H HG   . SER A 1 205 ? 111.418 110.339 147.241 1.00 25.79  ?  205 SER A HG   1 
ATOM   933   N N    . GLY A 1 206 ? 113.469 107.573 146.673 1.00 24.47  ?  206 GLY A N    1 
ATOM   934   C CA   . GLY A 1 206 ? 114.636 107.699 145.823 1.00 24.47  ?  206 GLY A CA   1 
ATOM   935   C C    . GLY A 1 206 ? 114.518 108.719 144.714 1.00 24.47  ?  206 GLY A C    1 
ATOM   936   O O    . GLY A 1 206 ? 115.495 108.934 143.990 1.00 24.47  ?  206 GLY A O    1 
ATOM   937   H H    . GLY A 1 206 ? 112.974 106.893 146.492 1.00 24.47  ?  206 GLY A H    1 
ATOM   938   H HA2  . GLY A 1 206 ? 115.399 107.940 146.370 1.00 24.47  ?  206 GLY A HA2  1 
ATOM   939   H HA3  . GLY A 1 206 ? 114.819 106.838 145.417 1.00 24.47  ?  206 GLY A HA3  1 
ATOM   940   N N    . ILE A 1 207 ? 113.357 109.353 144.554 1.00 25.01  ?  207 ILE A N    1 
ATOM   941   C CA   . ILE A 1 207 ? 113.170 110.368 143.525 1.00 25.01  ?  207 ILE A CA   1 
ATOM   942   C C    . ILE A 1 207 ? 111.991 111.234 143.933 1.00 25.01  ?  207 ILE A C    1 
ATOM   943   O O    . ILE A 1 207 ? 111.064 110.771 144.603 1.00 25.01  ?  207 ILE A O    1 
ATOM   944   C CB   . ILE A 1 207 ? 112.958 109.720 142.132 1.00 25.01  ?  207 ILE A CB   1 
ATOM   945   C CG1  . ILE A 1 207 ? 113.252 110.731 141.021 1.00 25.01  ?  207 ILE A CG1  1 
ATOM   946   C CG2  . ILE A 1 207 ? 111.541 109.177 142.003 1.00 25.01  ?  207 ILE A CG2  1 
ATOM   947   C CD1  . ILE A 1 207 ? 113.670 110.090 139.716 1.00 25.01  ?  207 ILE A CD1  1 
ATOM   948   H H    . ILE A 1 207 ? 112.658 109.211 145.035 1.00 25.01  ?  207 ILE A H    1 
ATOM   949   H HA   . ILE A 1 207 ? 113.960 110.929 143.486 1.00 25.01  ?  207 ILE A HA   1 
ATOM   950   H HB   . ILE A 1 207 ? 113.578 108.979 142.043 1.00 25.01  ?  207 ILE A HB   1 
ATOM   951   H HG12 . ILE A 1 207 ? 112.454 111.255 140.852 1.00 25.01  ?  207 ILE A HG12 1 
ATOM   952   H HG13 . ILE A 1 207 ? 113.973 111.314 141.306 1.00 25.01  ?  207 ILE A HG13 1 
ATOM   953   H HG21 . ILE A 1 207 ? 111.306 108.711 142.821 1.00 25.01  ?  207 ILE A HG21 1 
ATOM   954   H HG22 . ILE A 1 207 ? 110.929 109.914 141.854 1.00 25.01  ?  207 ILE A HG22 1 
ATOM   955   H HG23 . ILE A 1 207 ? 111.508 108.565 141.252 1.00 25.01  ?  207 ILE A HG23 1 
ATOM   956   H HD11 . ILE A 1 207 ? 113.915 110.785 139.087 1.00 25.01  ?  207 ILE A HD11 1 
ATOM   957   H HD12 . ILE A 1 207 ? 114.430 109.509 139.880 1.00 25.01  ?  207 ILE A HD12 1 
ATOM   958   H HD13 . ILE A 1 207 ? 112.927 109.573 139.368 1.00 25.01  ?  207 ILE A HD13 1 
ATOM   959   N N    . PHE A 1 208 ? 112.027 112.500 143.523 1.00 27.42  ?  208 PHE A N    1 
ATOM   960   C CA   . PHE A 1 208 ? 110.975 113.459 143.826 1.00 27.42  ?  208 PHE A CA   1 
ATOM   961   C C    . PHE A 1 208 ? 110.464 114.066 142.529 1.00 27.42  ?  208 PHE A C    1 
ATOM   962   O O    . PHE A 1 208 ? 111.244 114.337 141.611 1.00 27.42  ?  208 PHE A O    1 
ATOM   963   C CB   . PHE A 1 208 ? 111.480 114.565 144.760 1.00 27.42  ?  208 PHE A CB   1 
ATOM   964   C CG   . PHE A 1 208 ? 111.980 114.060 146.083 1.00 27.42  ?  208 PHE A CG   1 
ATOM   965   C CD1  . PHE A 1 208 ? 111.112 113.476 146.990 1.00 27.42  ?  208 PHE A CD1  1 
ATOM   966   C CD2  . PHE A 1 208 ? 113.319 114.168 146.419 1.00 27.42  ?  208 PHE A CD2  1 
ATOM   967   C CE1  . PHE A 1 208 ? 111.570 113.010 148.208 1.00 27.42  ?  208 PHE A CE1  1 
ATOM   968   C CE2  . PHE A 1 208 ? 113.782 113.704 147.636 1.00 27.42  ?  208 PHE A CE2  1 
ATOM   969   C CZ   . PHE A 1 208 ? 112.907 113.124 148.531 1.00 27.42  ?  208 PHE A CZ   1 
ATOM   970   H H    . PHE A 1 208 ? 112.669 112.833 143.057 1.00 27.42  ?  208 PHE A H    1 
ATOM   971   H HA   . PHE A 1 208 ? 110.237 113.005 144.261 1.00 27.42  ?  208 PHE A HA   1 
ATOM   972   H HB2  . PHE A 1 208 ? 112.211 115.032 144.326 1.00 27.42  ?  208 PHE A HB2  1 
ATOM   973   H HB3  . PHE A 1 208 ? 110.753 115.183 144.934 1.00 27.42  ?  208 PHE A HB3  1 
ATOM   974   H HD1  . PHE A 1 208 ? 110.210 113.396 146.778 1.00 27.42  ?  208 PHE A HD1  1 
ATOM   975   H HD2  . PHE A 1 208 ? 113.913 114.558 145.820 1.00 27.42  ?  208 PHE A HD2  1 
ATOM   976   H HE1  . PHE A 1 208 ? 110.977 112.620 148.810 1.00 27.42  ?  208 PHE A HE1  1 
ATOM   977   H HE2  . PHE A 1 208 ? 114.684 113.782 147.851 1.00 27.42  ?  208 PHE A HE2  1 
ATOM   978   H HZ   . PHE A 1 208 ? 113.217 112.811 149.350 1.00 27.42  ?  208 PHE A HZ   1 
ATOM   979   N N    . GLU A 1 209 ? 109.152 114.278 142.459 1.00 32.85  ?  209 GLU A N    1 
ATOM   980   C CA   . GLU A 1 209 ? 108.496 114.800 141.268 1.00 32.85  ?  209 GLU A CA   1 
ATOM   981   C C    . GLU A 1 209 ? 107.827 116.126 141.592 1.00 32.85  ?  209 GLU A C    1 
ATOM   982   O O    . GLU A 1 209 ? 107.075 116.226 142.568 1.00 32.85  ?  209 GLU A O    1 
ATOM   983   C CB   . GLU A 1 209 ? 107.461 113.808 140.732 1.00 32.85  ?  209 GLU A CB   1 
ATOM   984   C CG   . GLU A 1 209 ? 106.753 114.280 139.471 1.00 32.85  ?  209 GLU A CG   1 
ATOM   985   C CD   . GLU A 1 209 ? 106.418 113.145 138.522 1.00 32.85  ?  209 GLU A CD   1 
ATOM   986   O OE1  . GLU A 1 209 ? 106.379 111.980 138.972 1.00 32.85  ?  209 GLU A OE1  1 
ATOM   987   O OE2  . GLU A 1 209 ? 106.190 113.419 137.325 1.00 32.85  -1 209 GLU A OE2  1 
ATOM   988   H H    . GLU A 1 209 ? 108.609 114.122 143.108 1.00 32.85  ?  209 GLU A H    1 
ATOM   989   H HA   . GLU A 1 209 ? 109.157 114.953 140.576 1.00 32.85  ?  209 GLU A HA   1 
ATOM   990   H HB2  . GLU A 1 209 ? 107.910 112.973 140.528 1.00 32.85  ?  209 GLU A HB2  1 
ATOM   991   H HB3  . GLU A 1 209 ? 106.786 113.660 141.414 1.00 32.85  ?  209 GLU A HB3  1 
ATOM   992   H HG2  . GLU A 1 209 ? 105.923 114.717 139.720 1.00 32.85  ?  209 GLU A HG2  1 
ATOM   993   H HG3  . GLU A 1 209 ? 107.328 114.904 139.001 1.00 32.85  ?  209 GLU A HG3  1 
ATOM   994   N N    . THR A 1 210 ? 108.104 117.138 140.775 1.00 36.73  ?  210 THR A N    1 
ATOM   995   C CA   . THR A 1 210 ? 107.459 118.440 140.869 1.00 36.73  ?  210 THR A CA   1 
ATOM   996   C C    . THR A 1 210 ? 106.766 118.737 139.547 1.00 36.73  ?  210 THR A C    1 
ATOM   997   O O    . THR A 1 210 ? 107.399 118.690 138.486 1.00 36.73  ?  210 THR A O    1 
ATOM   998   C CB   . THR A 1 210 ? 108.474 119.538 141.196 1.00 36.73  ?  210 THR A CB   1 
ATOM   999   O OG1  . THR A 1 210 ? 109.045 119.297 142.488 1.00 36.73  ?  210 THR A OG1  1 
ATOM   1000  C CG2  . THR A 1 210 ? 107.807 120.908 141.187 1.00 36.73  ?  210 THR A CG2  1 
ATOM   1001  H H    . THR A 1 210 ? 108.682 117.090 140.139 1.00 36.73  ?  210 THR A H    1 
ATOM   1002  H HA   . THR A 1 210 ? 106.789 118.422 141.570 1.00 36.73  ?  210 THR A HA   1 
ATOM   1003  H HB   . THR A 1 210 ? 109.177 119.536 140.528 1.00 36.73  ?  210 THR A HB   1 
ATOM   1004  H HG1  . THR A 1 210 ? 109.430 118.551 142.498 1.00 36.73  ?  210 THR A HG1  1 
ATOM   1005  H HG21 . THR A 1 210 ? 108.382 121.559 141.617 1.00 36.73  ?  210 THR A HG21 1 
ATOM   1006  H HG22 . THR A 1 210 ? 106.964 120.868 141.665 1.00 36.73  ?  210 THR A HG22 1 
ATOM   1007  H HG23 . THR A 1 210 ? 107.638 121.191 140.275 1.00 36.73  ?  210 THR A HG23 1 
ATOM   1008  N N    . LYS A 1 211 ? 105.473 119.041 139.613 1.00 35.44  ?  211 LYS A N    1 
ATOM   1009  C CA   . LYS A 1 211 ? 104.658 119.287 138.431 1.00 35.44  ?  211 LYS A CA   1 
ATOM   1010  C C    . LYS A 1 211 ? 104.230 120.747 138.401 1.00 35.44  ?  211 LYS A C    1 
ATOM   1011  O O    . LYS A 1 211 ? 103.698 121.264 139.389 1.00 35.44  ?  211 LYS A O    1 
ATOM   1012  C CB   . LYS A 1 211 ? 103.430 118.374 138.418 1.00 35.44  ?  211 LYS A CB   1 
ATOM   1013  C CG   . LYS A 1 211 ? 103.765 116.896 138.292 1.00 35.44  ?  211 LYS A CG   1 
ATOM   1014  C CD   . LYS A 1 211 ? 102.540 116.070 137.930 1.00 35.44  ?  211 LYS A CD   1 
ATOM   1015  C CE   . LYS A 1 211 ? 101.650 115.831 139.139 1.00 35.44  ?  211 LYS A CE   1 
ATOM   1016  N NZ   . LYS A 1 211 ? 100.623 114.785 138.877 1.00 35.44  1  211 LYS A NZ   1 
ATOM   1017  H H    . LYS A 1 211 ? 105.037 119.113 140.350 1.00 35.44  ?  211 LYS A H    1 
ATOM   1018  H HA   . LYS A 1 211 ? 105.179 119.106 137.634 1.00 35.44  ?  211 LYS A HA   1 
ATOM   1019  H HB2  . LYS A 1 211 ? 102.939 118.498 139.245 1.00 35.44  ?  211 LYS A HB2  1 
ATOM   1020  H HB3  . LYS A 1 211 ? 102.869 118.617 137.664 1.00 35.44  ?  211 LYS A HB3  1 
ATOM   1021  H HG2  . LYS A 1 211 ? 104.428 116.777 137.595 1.00 35.44  ?  211 LYS A HG2  1 
ATOM   1022  H HG3  . LYS A 1 211 ? 104.109 116.574 139.140 1.00 35.44  ?  211 LYS A HG3  1 
ATOM   1023  H HD2  . LYS A 1 211 ? 102.022 116.541 137.259 1.00 35.44  ?  211 LYS A HD2  1 
ATOM   1024  H HD3  . LYS A 1 211 ? 102.826 115.208 137.589 1.00 35.44  ?  211 LYS A HD3  1 
ATOM   1025  H HE2  . LYS A 1 211 ? 102.196 115.538 139.885 1.00 35.44  ?  211 LYS A HE2  1 
ATOM   1026  H HE3  . LYS A 1 211 ? 101.191 116.655 139.364 1.00 35.44  ?  211 LYS A HE3  1 
ATOM   1027  H HZ1  . LYS A 1 211 ? 100.115 114.670 139.599 1.00 35.44  ?  211 LYS A HZ1  1 
ATOM   1028  H HZ2  . LYS A 1 211 ? 100.107 115.030 138.195 1.00 35.44  ?  211 LYS A HZ2  1 
ATOM   1029  H HZ3  . LYS A 1 211 ? 101.020 114.013 138.677 1.00 35.44  ?  211 LYS A HZ3  1 
ATOM   1030  N N    . PHE A 1 212 ? 104.464 121.404 137.268 1.00 34.59  ?  212 PHE A N    1 
ATOM   1031  C CA   . PHE A 1 212 ? 104.077 122.795 137.087 1.00 34.59  ?  212 PHE A CA   1 
ATOM   1032  C C    . PHE A 1 212 ? 103.656 123.000 135.640 1.00 34.59  ?  212 PHE A C    1 
ATOM   1033  O O    . PHE A 1 212 ? 104.102 122.289 134.736 1.00 34.59  ?  212 PHE A O    1 
ATOM   1034  C CB   . PHE A 1 212 ? 105.216 123.752 137.459 1.00 34.59  ?  212 PHE A CB   1 
ATOM   1035  C CG   . PHE A 1 212 ? 106.457 123.570 136.631 1.00 34.59  ?  212 PHE A CG   1 
ATOM   1036  C CD1  . PHE A 1 212 ? 107.306 122.498 136.855 1.00 34.59  ?  212 PHE A CD1  1 
ATOM   1037  C CD2  . PHE A 1 212 ? 106.776 124.471 135.629 1.00 34.59  ?  212 PHE A CD2  1 
ATOM   1038  C CE1  . PHE A 1 212 ? 108.447 122.329 136.095 1.00 34.59  ?  212 PHE A CE1  1 
ATOM   1039  C CE2  . PHE A 1 212 ? 107.916 124.306 134.866 1.00 34.59  ?  212 PHE A CE2  1 
ATOM   1040  C CZ   . PHE A 1 212 ? 108.753 123.234 135.100 1.00 34.59  ?  212 PHE A CZ   1 
ATOM   1041  H H    . PHE A 1 212 ? 104.852 121.060 136.582 1.00 34.59  ?  212 PHE A H    1 
ATOM   1042  H HA   . PHE A 1 212 ? 103.316 122.992 137.656 1.00 34.59  ?  212 PHE A HA   1 
ATOM   1043  H HB2  . PHE A 1 212 ? 104.910 124.664 137.336 1.00 34.59  ?  212 PHE A HB2  1 
ATOM   1044  H HB3  . PHE A 1 212 ? 105.456 123.608 138.387 1.00 34.59  ?  212 PHE A HB3  1 
ATOM   1045  H HD1  . PHE A 1 212 ? 107.104 121.885 137.525 1.00 34.59  ?  212 PHE A HD1  1 
ATOM   1046  H HD2  . PHE A 1 212 ? 106.215 125.195 135.467 1.00 34.59  ?  212 PHE A HD2  1 
ATOM   1047  H HE1  . PHE A 1 212 ? 109.009 121.605 136.255 1.00 34.59  ?  212 PHE A HE1  1 
ATOM   1048  H HE2  . PHE A 1 212 ? 108.120 124.918 134.195 1.00 34.59  ?  212 PHE A HE2  1 
ATOM   1049  H HZ   . PHE A 1 212 ? 109.521 123.121 134.587 1.00 34.59  ?  212 PHE A HZ   1 
ATOM   1050  N N    . GLN A 1 213 ? 102.789 123.986 135.431 1.00 36.39  ?  213 GLN A N    1 
ATOM   1051  C CA   . GLN A 1 213 ? 102.264 124.314 134.113 1.00 36.39  ?  213 GLN A CA   1 
ATOM   1052  C C    . GLN A 1 213 ? 102.725 125.708 133.713 1.00 36.39  ?  213 GLN A C    1 
ATOM   1053  O O    . GLN A 1 213 ? 102.619 126.652 134.504 1.00 36.39  ?  213 GLN A O    1 
ATOM   1054  C CB   . GLN A 1 213 ? 100.736 124.238 134.096 1.00 36.39  ?  213 GLN A CB   1 
ATOM   1055  C CG   . GLN A 1 213 ? 100.184 122.836 134.290 1.00 36.39  ?  213 GLN A CG   1 
ATOM   1056  C CD   . GLN A 1 213 ? 98.668  122.802 134.286 1.00 36.39  ?  213 GLN A CD   1 
ATOM   1057  O OE1  . GLN A 1 213 ? 98.013  123.841 134.203 1.00 36.39  ?  213 GLN A OE1  1 
ATOM   1058  N NE2  . GLN A 1 213 ? 98.103  121.604 134.376 1.00 36.39  ?  213 GLN A NE2  1 
ATOM   1059  H H    . GLN A 1 213 ? 102.482 124.492 136.056 1.00 36.39  ?  213 GLN A H    1 
ATOM   1060  H HA   . GLN A 1 213 ? 102.607 123.681 133.463 1.00 36.39  ?  213 GLN A HA   1 
ATOM   1061  H HB2  . GLN A 1 213 ? 100.388 124.795 134.810 1.00 36.39  ?  213 GLN A HB2  1 
ATOM   1062  H HB3  . GLN A 1 213 ? 100.417 124.566 133.240 1.00 36.39  ?  213 GLN A HB3  1 
ATOM   1063  H HG2  . GLN A 1 213 ? 100.499 122.270 133.569 1.00 36.39  ?  213 GLN A HG2  1 
ATOM   1064  H HG3  . GLN A 1 213 ? 100.490 122.491 135.143 1.00 36.39  ?  213 GLN A HG3  1 
ATOM   1065  H HE21 . GLN A 1 213 ? 98.594  120.900 134.432 1.00 36.39  ?  213 GLN A HE21 1 
ATOM   1066  H HE22 . GLN A 1 213 ? 97.246  121.532 134.378 1.00 36.39  ?  213 GLN A HE22 1 
ATOM   1067  N N    . VAL A 1 214 ? 103.234 125.831 132.491 1.00 34.69  ?  214 VAL A N    1 
ATOM   1068  C CA   . VAL A 1 214 ? 103.682 127.103 131.936 1.00 34.69  ?  214 VAL A CA   1 
ATOM   1069  C C    . VAL A 1 214 ? 102.946 127.314 130.622 1.00 34.69  ?  214 VAL A C    1 
ATOM   1070  O O    . VAL A 1 214 ? 103.092 126.514 129.689 1.00 34.69  ?  214 VAL A O    1 
ATOM   1071  C CB   . VAL A 1 214 ? 105.203 127.130 131.721 1.00 34.69  ?  214 VAL A CB   1 
ATOM   1072  C CG1  . VAL A 1 214 ? 105.651 128.508 131.253 1.00 34.69  ?  214 VAL A CG1  1 
ATOM   1073  C CG2  . VAL A 1 214 ? 105.929 126.724 132.992 1.00 34.69  ?  214 VAL A CG2  1 
ATOM   1074  H H    . VAL A 1 214 ? 103.333 125.171 131.948 1.00 34.69  ?  214 VAL A H    1 
ATOM   1075  H HA   . VAL A 1 214 ? 103.445 127.824 132.540 1.00 34.69  ?  214 VAL A HA   1 
ATOM   1076  H HB   . VAL A 1 214 ? 105.433 126.490 131.029 1.00 34.69  ?  214 VAL A HB   1 
ATOM   1077  H HG11 . VAL A 1 214 ? 106.620 128.529 131.220 1.00 34.69  ?  214 VAL A HG11 1 
ATOM   1078  H HG12 . VAL A 1 214 ? 105.287 128.679 130.370 1.00 34.69  ?  214 VAL A HG12 1 
ATOM   1079  H HG13 . VAL A 1 214 ? 105.328 129.174 131.880 1.00 34.69  ?  214 VAL A HG13 1 
ATOM   1080  H HG21 . VAL A 1 214 ? 105.689 127.339 133.703 1.00 34.69  ?  214 VAL A HG21 1 
ATOM   1081  H HG22 . VAL A 1 214 ? 106.884 126.758 132.830 1.00 34.69  ?  214 VAL A HG22 1 
ATOM   1082  H HG23 . VAL A 1 214 ? 105.669 125.821 133.233 1.00 34.69  ?  214 VAL A HG23 1 
ATOM   1083  N N    . ASP A 1 215 ? 102.163 128.389 130.545 1.00 35.57  ?  215 ASP A N    1 
ATOM   1084  C CA   . ASP A 1 215 ? 101.357 128.672 129.359 1.00 35.57  ?  215 ASP A CA   1 
ATOM   1085  C C    . ASP A 1 215 ? 100.495 127.466 128.996 1.00 35.57  ?  215 ASP A C    1 
ATOM   1086  O O    . ASP A 1 215 ? 100.351 127.103 127.826 1.00 35.57  ?  215 ASP A O    1 
ATOM   1087  C CB   . ASP A 1 215 ? 102.243 129.083 128.182 1.00 35.57  ?  215 ASP A CB   1 
ATOM   1088  C CG   . ASP A 1 215 ? 103.116 130.281 128.500 1.00 35.57  ?  215 ASP A CG   1 
ATOM   1089  O OD1  . ASP A 1 215 ? 102.931 130.883 129.578 1.00 35.57  ?  215 ASP A OD1  1 
ATOM   1090  O OD2  . ASP A 1 215 ? 103.987 130.620 127.672 1.00 35.57  -1 215 ASP A OD2  1 
ATOM   1091  H H    . ASP A 1 215 ? 102.081 128.974 131.170 1.00 35.57  ?  215 ASP A H    1 
ATOM   1092  H HA   . ASP A 1 215 ? 100.763 129.413 129.555 1.00 35.57  ?  215 ASP A HA   1 
ATOM   1093  H HB2  . ASP A 1 215 ? 102.823 128.342 127.948 1.00 35.57  ?  215 ASP A HB2  1 
ATOM   1094  H HB3  . ASP A 1 215 ? 101.679 129.315 127.427 1.00 35.57  ?  215 ASP A HB3  1 
ATOM   1095  N N    . LYS A 1 216 ? 99.917  126.835 130.018 1.00 36.36  ?  216 LYS A N    1 
ATOM   1096  C CA   . LYS A 1 216 ? 99.098  125.636 129.847 1.00 36.36  ?  216 LYS A CA   1 
ATOM   1097  C C    . LYS A 1 216 ? 99.883  124.509 129.182 1.00 36.36  ?  216 LYS A C    1 
ATOM   1098  O O    . LYS A 1 216 ? 99.337  123.741 128.385 1.00 36.36  ?  216 LYS A O    1 
ATOM   1099  C CB   . LYS A 1 216 ? 97.825  125.947 129.052 1.00 36.36  ?  216 LYS A CB   1 
ATOM   1100  C CG   . LYS A 1 216 ? 96.763  126.680 129.860 1.00 36.36  ?  216 LYS A CG   1 
ATOM   1101  C CD   . LYS A 1 216 ? 95.864  127.545 128.981 1.00 36.36  ?  216 LYS A CD   1 
ATOM   1102  C CE   . LYS A 1 216 ? 96.600  128.748 128.397 1.00 36.36  ?  216 LYS A CE   1 
ATOM   1103  N NZ   . LYS A 1 216 ? 97.403  129.486 129.411 1.00 36.36  1  216 LYS A NZ   1 
ATOM   1104  H H    . LYS A 1 216 ? 99.987  127.088 130.837 1.00 36.36  ?  216 LYS A H    1 
ATOM   1105  H HA   . LYS A 1 216 ? 98.824  125.324 130.723 1.00 36.36  ?  216 LYS A HA   1 
ATOM   1106  H HB2  . LYS A 1 216 ? 98.056  126.493 128.286 1.00 36.36  ?  216 LYS A HB2  1 
ATOM   1107  H HB3  . LYS A 1 216 ? 97.434  125.112 128.750 1.00 36.36  ?  216 LYS A HB3  1 
ATOM   1108  H HG2  . LYS A 1 216 ? 96.202  126.027 130.308 1.00 36.36  ?  216 LYS A HG2  1 
ATOM   1109  H HG3  . LYS A 1 216 ? 97.195  127.249 130.515 1.00 36.36  ?  216 LYS A HG3  1 
ATOM   1110  H HD2  . LYS A 1 216 ? 95.532  127.009 128.244 1.00 36.36  ?  216 LYS A HD2  1 
ATOM   1111  H HD3  . LYS A 1 216 ? 95.124  127.875 129.513 1.00 36.36  ?  216 LYS A HD3  1 
ATOM   1112  H HE2  . LYS A 1 216 ? 97.200  128.447 127.698 1.00 36.36  ?  216 LYS A HE2  1 
ATOM   1113  H HE3  . LYS A 1 216 ? 95.948  129.364 128.028 1.00 36.36  ?  216 LYS A HE3  1 
ATOM   1114  H HZ1  . LYS A 1 216 ? 97.732  130.233 129.054 1.00 36.36  ?  216 LYS A HZ1  1 
ATOM   1115  H HZ2  . LYS A 1 216 ? 96.892  129.700 130.108 1.00 36.36  ?  216 LYS A HZ2  1 
ATOM   1116  H HZ3  . LYS A 1 216 ? 98.078  128.980 129.693 1.00 36.36  ?  216 LYS A HZ3  1 
ATOM   1117  N N    . VAL A 1 217 ? 101.170 124.401 129.505 1.00 33.27  ?  217 VAL A N    1 
ATOM   1118  C CA   . VAL A 1 217 ? 102.029 123.322 129.030 1.00 33.27  ?  217 VAL A CA   1 
ATOM   1119  C C    . VAL A 1 217 ? 102.534 122.559 130.245 1.00 33.27  ?  217 VAL A C    1 
ATOM   1120  O O    . VAL A 1 217 ? 103.100 123.155 131.169 1.00 33.27  ?  217 VAL A O    1 
ATOM   1121  C CB   . VAL A 1 217 ? 103.200 123.857 128.188 1.00 33.27  ?  217 VAL A CB   1 
ATOM   1122  C CG1  . VAL A 1 217 ? 104.038 122.706 127.647 1.00 33.27  ?  217 VAL A CG1  1 
ATOM   1123  C CG2  . VAL A 1 217 ? 102.686 124.731 127.052 1.00 33.27  ?  217 VAL A CG2  1 
ATOM   1124  H H    . VAL A 1 217 ? 101.580 124.960 130.014 1.00 33.27  ?  217 VAL A H    1 
ATOM   1125  H HA   . VAL A 1 217 ? 101.512 122.713 128.480 1.00 33.27  ?  217 VAL A HA   1 
ATOM   1126  H HB   . VAL A 1 217 ? 103.772 124.401 128.751 1.00 33.27  ?  217 VAL A HB   1 
ATOM   1127  H HG11 . VAL A 1 217 ? 104.472 122.252 128.386 1.00 33.27  ?  217 VAL A HG11 1 
ATOM   1128  H HG12 . VAL A 1 217 ? 104.708 123.061 127.042 1.00 33.27  ?  217 VAL A HG12 1 
ATOM   1129  H HG13 . VAL A 1 217 ? 103.459 122.090 127.173 1.00 33.27  ?  217 VAL A HG13 1 
ATOM   1130  H HG21 . VAL A 1 217 ? 102.950 125.650 127.217 1.00 33.27  ?  217 VAL A HG21 1 
ATOM   1131  H HG22 . VAL A 1 217 ? 101.719 124.665 127.014 1.00 33.27  ?  217 VAL A HG22 1 
ATOM   1132  H HG23 . VAL A 1 217 ? 103.069 124.421 126.217 1.00 33.27  ?  217 VAL A HG23 1 
ATOM   1133  N N    . ASN A 1 218 ? 102.334 121.244 130.242 1.00 32.91  ?  218 ASN A N    1 
ATOM   1134  C CA   . ASN A 1 218 ? 102.677 120.406 131.383 1.00 32.91  ?  218 ASN A CA   1 
ATOM   1135  C C    . ASN A 1 218 ? 104.157 120.048 131.350 1.00 32.91  ?  218 ASN A C    1 
ATOM   1136  O O    . ASN A 1 218 ? 104.663 119.560 130.334 1.00 32.91  ?  218 ASN A O    1 
ATOM   1137  C CB   . ASN A 1 218 ? 101.827 119.134 131.388 1.00 32.91  ?  218 ASN A CB   1 
ATOM   1138  C CG   . ASN A 1 218 ? 100.349 119.422 131.559 1.00 32.91  ?  218 ASN A CG   1 
ATOM   1139  O OD1  . ASN A 1 218 ? 99.919  119.924 132.597 1.00 32.91  ?  218 ASN A OD1  1 
ATOM   1140  N ND2  . ASN A 1 218 ? 99.562  119.105 130.538 1.00 32.91  ?  218 ASN A ND2  1 
ATOM   1141  H H    . ASN A 1 218 ? 101.997 120.809 129.581 1.00 32.91  ?  218 ASN A H    1 
ATOM   1142  H HA   . ASN A 1 218 ? 102.500 120.893 132.203 1.00 32.91  ?  218 ASN A HA   1 
ATOM   1143  H HB2  . ASN A 1 218 ? 101.948 118.670 130.545 1.00 32.91  ?  218 ASN A HB2  1 
ATOM   1144  H HB3  . ASN A 1 218 ? 102.110 118.568 132.123 1.00 32.91  ?  218 ASN A HB3  1 
ATOM   1145  H HD21 . ASN A 1 218 ? 99.899  118.755 129.828 1.00 32.91  ?  218 ASN A HD21 1 
ATOM   1146  H HD22 . ASN A 1 218 ? 98.716  119.249 130.586 1.00 32.91  ?  218 ASN A HD22 1 
ATOM   1147  N N    . PHE A 1 219 ? 104.843 120.292 132.464 1.00 31.51  ?  219 PHE A N    1 
ATOM   1148  C CA   . PHE A 1 219 ? 106.248 119.947 132.628 1.00 31.51  ?  219 PHE A CA   1 
ATOM   1149  C C    . PHE A 1 219 ? 106.406 119.093 133.877 1.00 31.51  ?  219 PHE A C    1 
ATOM   1150  O O    . PHE A 1 219 ? 105.881 119.440 134.940 1.00 31.51  ?  219 PHE A O    1 
ATOM   1151  C CB   . PHE A 1 219 ? 107.120 121.201 132.735 1.00 31.51  ?  219 PHE A CB   1 
ATOM   1152  C CG   . PHE A 1 219 ? 107.235 121.973 131.452 1.00 31.51  ?  219 PHE A CG   1 
ATOM   1153  C CD1  . PHE A 1 219 ? 108.210 121.652 130.522 1.00 31.51  ?  219 PHE A CD1  1 
ATOM   1154  C CD2  . PHE A 1 219 ? 106.373 123.021 131.178 1.00 31.51  ?  219 PHE A CD2  1 
ATOM   1155  C CE1  . PHE A 1 219 ? 108.320 122.361 129.341 1.00 31.51  ?  219 PHE A CE1  1 
ATOM   1156  C CE2  . PHE A 1 219 ? 106.479 123.733 129.999 1.00 31.51  ?  219 PHE A CE2  1 
ATOM   1157  C CZ   . PHE A 1 219 ? 107.454 123.402 129.080 1.00 31.51  ?  219 PHE A CZ   1 
ATOM   1158  H H    . PHE A 1 219 ? 104.503 120.670 133.158 1.00 31.51  ?  219 PHE A H    1 
ATOM   1159  H HA   . PHE A 1 219 ? 106.548 119.430 131.864 1.00 31.51  ?  219 PHE A HA   1 
ATOM   1160  H HB2  . PHE A 1 219 ? 106.737 121.792 133.403 1.00 31.51  ?  219 PHE A HB2  1 
ATOM   1161  H HB3  . PHE A 1 219 ? 108.014 120.938 133.004 1.00 31.51  ?  219 PHE A HB3  1 
ATOM   1162  H HD1  . PHE A 1 219 ? 108.796 120.951 130.694 1.00 31.51  ?  219 PHE A HD1  1 
ATOM   1163  H HD2  . PHE A 1 219 ? 105.714 123.247 131.794 1.00 31.51  ?  219 PHE A HD2  1 
ATOM   1164  H HE1  . PHE A 1 219 ? 108.978 122.136 128.724 1.00 31.51  ?  219 PHE A HE1  1 
ATOM   1165  H HE2  . PHE A 1 219 ? 105.893 124.434 129.825 1.00 31.51  ?  219 PHE A HE2  1 
ATOM   1166  H HZ   . PHE A 1 219 ? 107.526 123.880 128.285 1.00 31.51  ?  219 PHE A HZ   1 
ATOM   1167  N N    . HIS A 1 220 ? 107.128 117.983 133.747 1.00 32.22  ?  220 HIS A N    1 
ATOM   1168  C CA   . HIS A 1 220 ? 107.427 117.094 134.862 1.00 32.22  ?  220 HIS A CA   1 
ATOM   1169  C C    . HIS A 1 220 ? 108.921 117.152 135.145 1.00 32.22  ?  220 HIS A C    1 
ATOM   1170  O O    . HIS A 1 220 ? 109.736 116.905 134.249 1.00 32.22  ?  220 HIS A O    1 
ATOM   1171  C CB   . HIS A 1 220 ? 106.990 115.661 134.557 1.00 32.22  ?  220 HIS A CB   1 
ATOM   1172  C CG   . HIS A 1 220 ? 105.512 115.446 134.654 1.00 32.22  ?  220 HIS A CG   1 
ATOM   1173  N ND1  . HIS A 1 220 ? 104.938 114.193 134.608 1.00 32.22  ?  220 HIS A ND1  1 
ATOM   1174  C CD2  . HIS A 1 220 ? 104.490 116.323 134.795 1.00 32.22  ?  220 HIS A CD2  1 
ATOM   1175  C CE1  . HIS A 1 220 ? 103.626 114.308 134.717 1.00 32.22  ?  220 HIS A CE1  1 
ATOM   1176  N NE2  . HIS A 1 220 ? 103.329 115.590 134.831 1.00 32.22  ?  220 HIS A NE2  1 
ATOM   1177  H H    . HIS A 1 220 ? 107.463 117.719 133.000 1.00 32.22  ?  220 HIS A H    1 
ATOM   1178  H HA   . HIS A 1 220 ? 106.955 117.395 135.654 1.00 32.22  ?  220 HIS A HA   1 
ATOM   1179  H HB2  . HIS A 1 220 ? 107.264 115.437 133.654 1.00 32.22  ?  220 HIS A HB2  1 
ATOM   1180  H HB3  . HIS A 1 220 ? 107.419 115.062 135.189 1.00 32.22  ?  220 HIS A HB3  1 
ATOM   1181  H HD2  . HIS A 1 220 ? 104.561 117.248 134.856 1.00 32.22  ?  220 HIS A HD2  1 
ATOM   1182  H HE1  . HIS A 1 220 ? 103.016 113.606 134.713 1.00 32.22  ?  220 HIS A HE1  1 
ATOM   1183  H HE2  . HIS A 1 220 ? 102.536 115.913 134.915 1.00 32.22  ?  220 HIS A HE2  1 
ATOM   1184  N N    . MET A 1 221 ? 109.273 117.478 136.384 1.00 31.76  ?  221 MET A N    1 
ATOM   1185  C CA   . MET A 1 221 ? 110.660 117.591 136.815 1.00 31.76  ?  221 MET A CA   1 
ATOM   1186  C C    . MET A 1 221 ? 110.952 116.515 137.849 1.00 31.76  ?  221 MET A C    1 
ATOM   1187  O O    . MET A 1 221 ? 110.183 116.337 138.799 1.00 31.76  ?  221 MET A O    1 
ATOM   1188  C CB   . MET A 1 221 ? 110.937 118.974 137.404 1.00 31.76  ?  221 MET A CB   1 
ATOM   1189  C CG   . MET A 1 221 ? 112.336 119.498 137.130 1.00 31.76  ?  221 MET A CG   1 
ATOM   1190  S SD   . MET A 1 221 ? 112.785 120.873 138.206 1.00 31.76  ?  221 MET A SD   1 
ATOM   1191  C CE   . MET A 1 221 ? 111.269 121.828 138.202 1.00 31.76  ?  221 MET A CE   1 
ATOM   1192  H H    . MET A 1 221 ? 108.709 117.642 137.012 1.00 31.76  ?  221 MET A H    1 
ATOM   1193  H HA   . MET A 1 221 ? 111.245 117.466 136.051 1.00 31.76  ?  221 MET A HA   1 
ATOM   1194  H HB2  . MET A 1 221 ? 110.305 119.602 137.022 1.00 31.76  ?  221 MET A HB2  1 
ATOM   1195  H HB3  . MET A 1 221 ? 110.819 118.933 138.366 1.00 31.76  ?  221 MET A HB3  1 
ATOM   1196  H HG2  . MET A 1 221 ? 112.975 118.783 137.274 1.00 31.76  ?  221 MET A HG2  1 
ATOM   1197  H HG3  . MET A 1 221 ? 112.384 119.806 136.211 1.00 31.76  ?  221 MET A HG3  1 
ATOM   1198  H HE1  . MET A 1 221 ? 111.044 122.060 137.287 1.00 31.76  ?  221 MET A HE1  1 
ATOM   1199  H HE2  . MET A 1 221 ? 111.405 122.632 138.724 1.00 31.76  ?  221 MET A HE2  1 
ATOM   1200  H HE3  . MET A 1 221 ? 110.557 121.301 138.597 1.00 31.76  ?  221 MET A HE3  1 
ATOM   1201  N N    . PHE A 1 222 ? 112.059 115.803 137.662 1.00 26.37  ?  222 PHE A N    1 
ATOM   1202  C CA   . PHE A 1 222 ? 112.465 114.726 138.552 1.00 26.37  ?  222 PHE A CA   1 
ATOM   1203  C C    . PHE A 1 222 ? 113.756 115.111 139.261 1.00 26.37  ?  222 PHE A C    1 
ATOM   1204  O O    . PHE A 1 222 ? 114.742 115.473 138.610 1.00 26.37  ?  222 PHE A O    1 
ATOM   1205  C CB   . PHE A 1 222 ? 112.655 113.421 137.776 1.00 26.37  ?  222 PHE A CB   1 
ATOM   1206  C CG   . PHE A 1 222 ? 111.387 112.887 137.175 1.00 26.37  ?  222 PHE A CG   1 
ATOM   1207  C CD1  . PHE A 1 222 ? 110.441 112.259 137.966 1.00 26.37  ?  222 PHE A CD1  1 
ATOM   1208  C CD2  . PHE A 1 222 ? 111.142 113.013 135.818 1.00 26.37  ?  222 PHE A CD2  1 
ATOM   1209  C CE1  . PHE A 1 222 ? 109.273 111.766 137.415 1.00 26.37  ?  222 PHE A CE1  1 
ATOM   1210  C CE2  . PHE A 1 222 ? 109.977 112.523 135.261 1.00 26.37  ?  222 PHE A CE2  1 
ATOM   1211  C CZ   . PHE A 1 222 ? 109.041 111.899 136.061 1.00 26.37  ?  222 PHE A CZ   1 
ATOM   1212  H H    . PHE A 1 222 ? 112.603 115.930 137.009 1.00 26.37  ?  222 PHE A H    1 
ATOM   1213  H HA   . PHE A 1 222 ? 111.779 114.583 139.223 1.00 26.37  ?  222 PHE A HA   1 
ATOM   1214  H HB2  . PHE A 1 222 ? 113.284 113.576 137.054 1.00 26.37  ?  222 PHE A HB2  1 
ATOM   1215  H HB3  . PHE A 1 222 ? 113.005 112.748 138.379 1.00 26.37  ?  222 PHE A HB3  1 
ATOM   1216  H HD1  . PHE A 1 222 ? 110.592 112.167 138.879 1.00 26.37  ?  222 PHE A HD1  1 
ATOM   1217  H HD2  . PHE A 1 222 ? 111.770 113.433 135.275 1.00 26.37  ?  222 PHE A HD2  1 
ATOM   1218  H HE1  . PHE A 1 222 ? 108.644 111.346 137.956 1.00 26.37  ?  222 PHE A HE1  1 
ATOM   1219  H HE2  . PHE A 1 222 ? 109.823 112.613 134.349 1.00 26.37  ?  222 PHE A HE2  1 
ATOM   1220  H HZ   . PHE A 1 222 ? 108.256 111.568 135.688 1.00 26.37  ?  222 PHE A HZ   1 
ATOM   1221  N N    . ASP A 1 223 ? 113.744 115.031 140.588 1.00 28.60  ?  223 ASP A N    1 
ATOM   1222  C CA   . ASP A 1 223 ? 114.918 115.286 141.413 1.00 28.60  ?  223 ASP A CA   1 
ATOM   1223  C C    . ASP A 1 223 ? 115.360 113.966 142.029 1.00 28.60  ?  223 ASP A C    1 
ATOM   1224  O O    . ASP A 1 223 ? 114.583 113.319 142.740 1.00 28.60  ?  223 ASP A O    1 
ATOM   1225  C CB   . ASP A 1 223 ? 114.613 116.319 142.499 1.00 28.60  ?  223 ASP A CB   1 
ATOM   1226  C CG   . ASP A 1 223 ? 115.783 116.544 143.436 1.00 28.60  ?  223 ASP A CG   1 
ATOM   1227  O OD1  . ASP A 1 223 ? 116.918 116.165 143.078 1.00 28.60  ?  223 ASP A OD1  1 
ATOM   1228  O OD2  . ASP A 1 223 ? 115.568 117.101 144.533 1.00 28.60  -1 223 ASP A OD2  1 
ATOM   1229  H H    . ASP A 1 223 ? 113.045 114.826 141.046 1.00 28.60  ?  223 ASP A H    1 
ATOM   1230  H HA   . ASP A 1 223 ? 115.639 115.625 140.860 1.00 28.60  ?  223 ASP A HA   1 
ATOM   1231  H HB2  . ASP A 1 223 ? 114.397 117.166 142.078 1.00 28.60  ?  223 ASP A HB2  1 
ATOM   1232  H HB3  . ASP A 1 223 ? 113.860 116.009 143.026 1.00 28.60  ?  223 ASP A HB3  1 
ATOM   1233  N N    . VAL A 1 224 ? 116.602 113.571 141.758 1.00 25.55  ?  224 VAL A N    1 
ATOM   1234  C CA   . VAL A 1 224 ? 117.105 112.272 142.189 1.00 25.55  ?  224 VAL A CA   1 
ATOM   1235  C C    . VAL A 1 224 ? 117.714 112.394 143.579 1.00 25.55  ?  224 VAL A C    1 
ATOM   1236  O O    . VAL A 1 224 ? 118.923 112.609 143.722 1.00 25.55  ?  224 VAL A O    1 
ATOM   1237  C CB   . VAL A 1 224 ? 118.131 111.710 141.188 1.00 25.55  ?  224 VAL A CB   1 
ATOM   1238  C CG1  . VAL A 1 224 ? 118.580 110.323 141.617 1.00 25.55  ?  224 VAL A CG1  1 
ATOM   1239  C CG2  . VAL A 1 224 ? 117.546 111.670 139.781 1.00 25.55  ?  224 VAL A CG2  1 
ATOM   1240  H H    . VAL A 1 224 ? 117.176 114.042 141.323 1.00 25.55  ?  224 VAL A H    1 
ATOM   1241  H HA   . VAL A 1 224 ? 116.364 111.648 142.240 1.00 25.55  ?  224 VAL A HA   1 
ATOM   1242  H HB   . VAL A 1 224 ? 118.910 112.287 141.174 1.00 25.55  ?  224 VAL A HB   1 
ATOM   1243  H HG11 . VAL A 1 224 ? 119.107 110.396 142.428 1.00 25.55  ?  224 VAL A HG11 1 
ATOM   1244  H HG12 . VAL A 1 224 ? 117.797 109.774 141.780 1.00 25.55  ?  224 VAL A HG12 1 
ATOM   1245  H HG13 . VAL A 1 224 ? 119.117 109.931 140.912 1.00 25.55  ?  224 VAL A HG13 1 
ATOM   1246  H HG21 . VAL A 1 224 ? 116.666 112.076 139.784 1.00 25.55  ?  224 VAL A HG21 1 
ATOM   1247  H HG22 . VAL A 1 224 ? 118.134 112.158 139.183 1.00 25.55  ?  224 VAL A HG22 1 
ATOM   1248  H HG23 . VAL A 1 224 ? 117.480 110.745 139.495 1.00 25.55  ?  224 VAL A HG23 1 
ATOM   1249  N N    . GLY A 1 225 ? 116.882 112.254 144.608 1.00 25.98  ?  225 GLY A N    1 
ATOM   1250  C CA   . GLY A 1 225 ? 117.379 112.272 145.966 1.00 25.98  ?  225 GLY A CA   1 
ATOM   1251  C C    . GLY A 1 225 ? 117.451 110.883 146.571 1.00 25.98  ?  225 GLY A C    1 
ATOM   1252  O O    . GLY A 1 225 ? 116.921 109.907 146.039 1.00 25.98  ?  225 GLY A O    1 
ATOM   1253  H H    . GLY A 1 225 ? 116.031 112.149 144.541 1.00 25.98  ?  225 GLY A H    1 
ATOM   1254  H HA2  . GLY A 1 225 ? 118.266 112.663 145.989 1.00 25.98  ?  225 GLY A HA2  1 
ATOM   1255  H HA3  . GLY A 1 225 ? 116.792 112.814 146.516 1.00 25.98  ?  225 GLY A HA3  1 
ATOM   1256  N N    . ALA A 1 226 ? 118.129 110.800 147.715 1.00 25.71  ?  226 ALA A N    1 
ATOM   1257  C CA   . ALA A 1 226 ? 118.264 109.544 148.454 1.00 25.71  ?  226 ALA A CA   1 
ATOM   1258  C C    . ALA A 1 226 ? 118.932 108.465 147.605 1.00 25.71  ?  226 ALA A C    1 
ATOM   1259  O O    . ALA A 1 226 ? 118.673 107.271 147.778 1.00 25.71  ?  226 ALA A O    1 
ATOM   1260  C CB   . ALA A 1 226 ? 116.906 109.059 148.964 1.00 25.71  ?  226 ALA A CB   1 
ATOM   1261  H H    . ALA A 1 226 ? 118.525 111.466 148.089 1.00 25.71  ?  226 ALA A H    1 
ATOM   1262  H HA   . ALA A 1 226 ? 118.829 109.700 149.227 1.00 25.71  ?  226 ALA A HA   1 
ATOM   1263  H HB1  . ALA A 1 226 ? 117.030 108.233 149.456 1.00 25.71  ?  226 ALA A HB1  1 
ATOM   1264  H HB2  . ALA A 1 226 ? 116.319 108.909 148.208 1.00 25.71  ?  226 ALA A HB2  1 
ATOM   1265  H HB3  . ALA A 1 226 ? 116.528 109.737 149.547 1.00 25.71  ?  226 ALA A HB3  1 
ATOM   1266  N N    . GLN A 1 227 ? 119.795 108.878 146.684 1.00 26.13  ?  227 GLN A N    1 
ATOM   1267  C CA   . GLN A 1 227 ? 120.543 107.962 145.836 1.00 26.13  ?  227 GLN A CA   1 
ATOM   1268  C C    . GLN A 1 227 ? 122.041 108.123 146.074 1.00 26.13  ?  227 GLN A C    1 
ATOM   1269  O O    . GLN A 1 227 ? 122.534 109.198 146.422 1.00 26.13  ?  227 GLN A O    1 
ATOM   1270  C CB   . GLN A 1 227 ? 120.211 108.198 144.359 1.00 26.13  ?  227 GLN A CB   1 
ATOM   1271  C CG   . GLN A 1 227 ? 118.791 107.823 143.967 1.00 26.13  ?  227 GLN A CG   1 
ATOM   1272  C CD   . GLN A 1 227 ? 118.501 106.348 144.164 1.00 26.13  ?  227 GLN A CD   1 
ATOM   1273  O OE1  . GLN A 1 227 ? 119.400 105.511 144.090 1.00 26.13  ?  227 GLN A OE1  1 
ATOM   1274  N NE2  . GLN A 1 227 ? 117.238 106.023 144.411 1.00 26.13  ?  227 GLN A NE2  1 
ATOM   1275  H H    . GLN A 1 227 ? 119.969 109.705 146.528 1.00 26.13  ?  227 GLN A H    1 
ATOM   1276  H HA   . GLN A 1 227 ? 120.303 107.049 146.058 1.00 26.13  ?  227 GLN A HA   1 
ATOM   1277  H HB2  . GLN A 1 227 ? 120.333 109.140 144.160 1.00 26.13  ?  227 GLN A HB2  1 
ATOM   1278  H HB3  . GLN A 1 227 ? 120.816 107.669 143.816 1.00 26.13  ?  227 GLN A HB3  1 
ATOM   1279  H HG2  . GLN A 1 227 ? 118.167 108.329 144.511 1.00 26.13  ?  227 GLN A HG2  1 
ATOM   1280  H HG3  . GLN A 1 227 ? 118.658 108.028 143.029 1.00 26.13  ?  227 GLN A HG3  1 
ATOM   1281  H HE21 . GLN A 1 227 ? 117.021 105.199 144.530 1.00 26.13  ?  227 GLN A HE21 1 
ATOM   1282  H HE22 . GLN A 1 227 ? 116.638 106.636 144.454 1.00 26.13  ?  227 GLN A HE22 1 
ATOM   1283  N N    . ARG A 1 228 ? 122.767 107.026 145.879 1.00 31.41  ?  228 ARG A N    1 
ATOM   1284  C CA   . ARG A 1 228 ? 124.209 107.040 146.051 1.00 31.41  ?  228 ARG A CA   1 
ATOM   1285  C C    . ARG A 1 228 ? 124.869 107.840 144.931 1.00 31.41  ?  228 ARG A C    1 
ATOM   1286  O O    . ARG A 1 228 ? 124.309 108.027 143.848 1.00 31.41  ?  228 ARG A O    1 
ATOM   1287  C CB   . ARG A 1 228 ? 124.760 105.613 146.082 1.00 31.41  ?  228 ARG A CB   1 
ATOM   1288  C CG   . ARG A 1 228 ? 124.504 104.891 147.397 1.00 31.41  ?  228 ARG A CG   1 
ATOM   1289  C CD   . ARG A 1 228 ? 124.987 103.449 147.362 1.00 31.41  ?  228 ARG A CD   1 
ATOM   1290  N NE   . ARG A 1 228 ? 126.420 103.351 147.082 1.00 31.41  ?  228 ARG A NE   1 
ATOM   1291  C CZ   . ARG A 1 228 ? 126.950 102.958 145.926 1.00 31.41  ?  228 ARG A CZ   1 
ATOM   1292  N NH1  . ARG A 1 228 ? 128.268 102.907 145.794 1.00 31.41  1  228 ARG A NH1  1 
ATOM   1293  N NH2  . ARG A 1 228 ? 126.179 102.618 144.900 1.00 31.41  ?  228 ARG A NH2  1 
ATOM   1294  H H    . ARG A 1 228 ? 122.445 106.263 145.647 1.00 31.41  ?  228 ARG A H    1 
ATOM   1295  H HA   . ARG A 1 228 ? 124.425 107.466 146.895 1.00 31.41  ?  228 ARG A HA   1 
ATOM   1296  H HB2  . ARG A 1 228 ? 124.340 105.100 145.374 1.00 31.41  ?  228 ARG A HB2  1 
ATOM   1297  H HB3  . ARG A 1 228 ? 125.719 105.645 145.942 1.00 31.41  ?  228 ARG A HB3  1 
ATOM   1298  H HG2  . ARG A 1 228 ? 124.975 105.351 148.109 1.00 31.41  ?  228 ARG A HG2  1 
ATOM   1299  H HG3  . ARG A 1 228 ? 123.550 104.886 147.576 1.00 31.41  ?  228 ARG A HG3  1 
ATOM   1300  H HD2  . ARG A 1 228 ? 124.830 103.050 148.231 1.00 31.41  ?  228 ARG A HD2  1 
ATOM   1301  H HD3  . ARG A 1 228 ? 124.492 102.963 146.687 1.00 31.41  ?  228 ARG A HD3  1 
ATOM   1302  H HE   . ARG A 1 228 ? 126.962 103.560 147.716 1.00 31.41  ?  228 ARG A HE   1 
ATOM   1303  H HH11 . ARG A 1 228 ? 128.775 103.126 146.454 1.00 31.41  ?  228 ARG A HH11 1 
ATOM   1304  H HH12 . ARG A 1 228 ? 128.616 102.656 145.049 1.00 31.41  ?  228 ARG A HH12 1 
ATOM   1305  H HH21 . ARG A 1 228 ? 125.324 102.645 144.965 1.00 31.41  ?  228 ARG A HH21 1 
ATOM   1306  H HH22 . ARG A 1 228 ? 126.542 102.368 144.161 1.00 31.41  ?  228 ARG A HH22 1 
ATOM   1307  N N    . ASP A 1 229 ? 126.083 108.315 145.210 1.00 35.57  ?  229 ASP A N    1 
ATOM   1308  C CA   . ASP A 1 229 ? 126.801 109.175 144.279 1.00 35.57  ?  229 ASP A CA   1 
ATOM   1309  C C    . ASP A 1 229 ? 127.235 108.455 143.008 1.00 35.57  ?  229 ASP A C    1 
ATOM   1310  O O    . ASP A 1 229 ? 127.674 109.119 142.063 1.00 35.57  ?  229 ASP A O    1 
ATOM   1311  C CB   . ASP A 1 229 ? 128.025 109.782 144.970 1.00 35.57  ?  229 ASP A CB   1 
ATOM   1312  C CG   . ASP A 1 229 ? 128.986 108.729 145.482 1.00 35.57  ?  229 ASP A CG   1 
ATOM   1313  O OD1  . ASP A 1 229 ? 128.577 107.554 145.596 1.00 35.57  ?  229 ASP A OD1  1 
ATOM   1314  O OD2  . ASP A 1 229 ? 130.149 109.077 145.775 1.00 35.57  -1 229 ASP A OD2  1 
ATOM   1315  H H    . ASP A 1 229 ? 126.511 108.151 145.937 1.00 35.57  ?  229 ASP A H    1 
ATOM   1316  H HA   . ASP A 1 229 ? 126.217 109.905 144.018 1.00 35.57  ?  229 ASP A HA   1 
ATOM   1317  H HB2  . ASP A 1 229 ? 128.501 110.341 144.337 1.00 35.57  ?  229 ASP A HB2  1 
ATOM   1318  H HB3  . ASP A 1 229 ? 127.730 110.313 145.726 1.00 35.57  ?  229 ASP A HB3  1 
ATOM   1319  N N    . GLU A 1 230 ? 127.132 107.129 142.959 1.00 32.50  ?  230 GLU A N    1 
ATOM   1320  C CA   . GLU A 1 230 ? 127.473 106.369 141.757 1.00 32.50  ?  230 GLU A CA   1 
ATOM   1321  C C    . GLU A 1 230 ? 126.336 106.530 140.756 1.00 32.50  ?  230 GLU A C    1 
ATOM   1322  O O    . GLU A 1 230 ? 125.358 105.780 140.780 1.00 32.50  ?  230 GLU A O    1 
ATOM   1323  C CB   . GLU A 1 230 ? 127.712 104.903 142.100 1.00 32.50  ?  230 GLU A CB   1 
ATOM   1324  C CG   . GLU A 1 230 ? 128.951 104.662 142.946 1.00 32.50  ?  230 GLU A CG   1 
ATOM   1325  C CD   . GLU A 1 230 ? 129.656 103.367 142.594 1.00 32.50  ?  230 GLU A CD   1 
ATOM   1326  O OE1  . GLU A 1 230 ? 128.981 102.318 142.532 1.00 32.50  ?  230 GLU A OE1  1 
ATOM   1327  O OE2  . GLU A 1 230 ? 130.886 103.398 142.379 1.00 32.50  -1 230 GLU A OE2  1 
ATOM   1328  H H    . GLU A 1 230 ? 126.865 106.640 143.614 1.00 32.50  ?  230 GLU A H    1 
ATOM   1329  H HA   . GLU A 1 230 ? 128.283 106.730 141.365 1.00 32.50  ?  230 GLU A HA   1 
ATOM   1330  H HB2  . GLU A 1 230 ? 126.946 104.569 142.593 1.00 32.50  ?  230 GLU A HB2  1 
ATOM   1331  H HB3  . GLU A 1 230 ? 127.815 104.403 141.275 1.00 32.50  ?  230 GLU A HB3  1 
ATOM   1332  H HG2  . GLU A 1 230 ? 129.576 105.390 142.809 1.00 32.50  ?  230 GLU A HG2  1 
ATOM   1333  H HG3  . GLU A 1 230 ? 128.693 104.618 143.880 1.00 32.50  ?  230 GLU A HG3  1 
ATOM   1334  N N    . ARG A 1 231 ? 126.464 107.516 139.866 1.00 25.04  ?  231 ARG A N    1 
ATOM   1335  C CA   . ARG A 1 231 ? 125.394 107.855 138.935 1.00 25.04  ?  231 ARG A CA   1 
ATOM   1336  C C    . ARG A 1 231 ? 125.467 107.084 137.624 1.00 25.04  ?  231 ARG A C    1 
ATOM   1337  O O    . ARG A 1 231 ? 124.540 107.190 136.815 1.00 25.04  ?  231 ARG A O    1 
ATOM   1338  C CB   . ARG A 1 231 ? 125.427 109.354 138.627 1.00 25.04  ?  231 ARG A CB   1 
ATOM   1339  C CG   . ARG A 1 231 ? 125.470 110.248 139.854 1.00 25.04  ?  231 ARG A CG   1 
ATOM   1340  C CD   . ARG A 1 231 ? 125.278 111.707 139.475 1.00 25.04  ?  231 ARG A CD   1 
ATOM   1341  N NE   . ARG A 1 231 ? 125.437 112.600 140.620 1.00 25.04  ?  231 ARG A NE   1 
ATOM   1342  C CZ   . ARG A 1 231 ? 126.610 112.992 141.109 1.00 25.04  ?  231 ARG A CZ   1 
ATOM   1343  N NH1  . ARG A 1 231 ? 126.652 113.808 142.153 1.00 25.04  1  231 ARG A NH1  1 
ATOM   1344  N NH2  . ARG A 1 231 ? 127.742 112.571 140.559 1.00 25.04  ?  231 ARG A NH2  1 
ATOM   1345  H H    . ARG A 1 231 ? 127.166 108.005 139.784 1.00 25.04  ?  231 ARG A H    1 
ATOM   1346  H HA   . ARG A 1 231 ? 124.543 107.654 139.350 1.00 25.04  ?  231 ARG A HA   1 
ATOM   1347  H HB2  . ARG A 1 231 ? 126.216 109.544 138.096 1.00 25.04  ?  231 ARG A HB2  1 
ATOM   1348  H HB3  . ARG A 1 231 ? 124.631 109.584 138.123 1.00 25.04  ?  231 ARG A HB3  1 
ATOM   1349  H HG2  . ARG A 1 231 ? 124.763 109.992 140.465 1.00 25.04  ?  231 ARG A HG2  1 
ATOM   1350  H HG3  . ARG A 1 231 ? 126.335 110.158 140.284 1.00 25.04  ?  231 ARG A HG3  1 
ATOM   1351  H HD2  . ARG A 1 231 ? 125.932 111.952 138.803 1.00 25.04  ?  231 ARG A HD2  1 
ATOM   1352  H HD3  . ARG A 1 231 ? 124.381 111.827 139.125 1.00 25.04  ?  231 ARG A HD3  1 
ATOM   1353  H HE   . ARG A 1 231 ? 124.725 112.924 140.978 1.00 25.04  ?  231 ARG A HE   1 
ATOM   1354  H HH11 . ARG A 1 231 ? 125.922 114.084 142.514 1.00 25.04  ?  231 ARG A HH11 1 
ATOM   1355  H HH12 . ARG A 1 231 ? 127.411 114.061 142.471 1.00 25.04  ?  231 ARG A HH12 1 
ATOM   1356  H HH21 . ARG A 1 231 ? 127.725 112.042 139.882 1.00 25.04  ?  231 ARG A HH21 1 
ATOM   1357  H HH22 . ARG A 1 231 ? 128.496 112.829 140.882 1.00 25.04  ?  231 ARG A HH22 1 
ATOM   1358  N N    . ARG A 1 232 ? 126.528 106.310 137.395 1.00 26.20  ?  232 ARG A N    1 
ATOM   1359  C CA   . ARG A 1 232 ? 126.756 105.739 136.072 1.00 26.20  ?  232 ARG A CA   1 
ATOM   1360  C C    . ARG A 1 232 ? 125.664 104.764 135.646 1.00 26.20  ?  232 ARG A C    1 
ATOM   1361  O O    . ARG A 1 232 ? 125.515 104.514 134.445 1.00 26.20  ?  232 ARG A O    1 
ATOM   1362  C CB   . ARG A 1 232 ? 128.119 105.048 136.039 1.00 26.20  ?  232 ARG A CB   1 
ATOM   1363  C CG   . ARG A 1 232 ? 128.217 103.797 136.894 1.00 26.20  ?  232 ARG A CG   1 
ATOM   1364  C CD   . ARG A 1 232 ? 129.568 103.141 136.711 1.00 26.20  ?  232 ARG A CD   1 
ATOM   1365  N NE   . ARG A 1 232 ? 129.757 101.982 137.579 1.00 26.20  ?  232 ARG A NE   1 
ATOM   1366  C CZ   . ARG A 1 232 ? 130.255 102.039 138.811 1.00 26.20  ?  232 ARG A CZ   1 
ATOM   1367  N NH1  . ARG A 1 232 ? 130.393 100.927 139.516 1.00 26.20  1  232 ARG A NH1  1 
ATOM   1368  N NH2  . ARG A 1 232 ? 130.605 103.201 139.346 1.00 26.20  ?  232 ARG A NH2  1 
ATOM   1369  H H    . ARG A 1 232 ? 127.122 106.102 137.981 1.00 26.20  ?  232 ARG A H    1 
ATOM   1370  H HA   . ARG A 1 232 ? 126.775 106.459 135.423 1.00 26.20  ?  232 ARG A HA   1 
ATOM   1371  H HB2  . ARG A 1 232 ? 128.315 104.794 135.123 1.00 26.20  ?  232 ARG A HB2  1 
ATOM   1372  H HB3  . ARG A 1 232 ? 128.791 105.672 136.354 1.00 26.20  ?  232 ARG A HB3  1 
ATOM   1373  H HG2  . ARG A 1 232 ? 128.113 104.034 137.829 1.00 26.20  ?  232 ARG A HG2  1 
ATOM   1374  H HG3  . ARG A 1 232 ? 127.535 103.163 136.626 1.00 26.20  ?  232 ARG A HG3  1 
ATOM   1375  H HD2  . ARG A 1 232 ? 129.643 102.837 135.792 1.00 26.20  ?  232 ARG A HD2  1 
ATOM   1376  H HD3  . ARG A 1 232 ? 130.263 103.788 136.901 1.00 26.20  ?  232 ARG A HD3  1 
ATOM   1377  H HE   . ARG A 1 232 ? 129.585 101.206 137.252 1.00 26.20  ?  232 ARG A HE   1 
ATOM   1378  H HH11 . ARG A 1 232 ? 130.166 100.174 139.172 1.00 26.20  ?  232 ARG A HH11 1 
ATOM   1379  H HH12 . ARG A 1 232 ? 130.710 100.958 140.315 1.00 26.20  ?  232 ARG A HH12 1 
ATOM   1380  H HH21 . ARG A 1 232 ? 130.520 103.930 138.900 1.00 26.20  ?  232 ARG A HH21 1 
ATOM   1381  H HH22 . ARG A 1 232 ? 130.922 103.224 140.145 1.00 26.20  ?  232 ARG A HH22 1 
ATOM   1382  N N    . LYS A 1 233 ? 124.900 104.210 136.587 1.00 24.03  ?  233 LYS A N    1 
ATOM   1383  C CA   . LYS A 1 233 ? 123.885 103.222 136.235 1.00 24.03  ?  233 LYS A CA   1 
ATOM   1384  C C    . LYS A 1 233 ? 122.490 103.830 136.128 1.00 24.03  ?  233 LYS A C    1 
ATOM   1385  O O    . LYS A 1 233 ? 121.845 103.720 135.080 1.00 24.03  ?  233 LYS A O    1 
ATOM   1386  C CB   . LYS A 1 233 ? 123.886 102.081 137.259 1.00 24.03  ?  233 LYS A CB   1 
ATOM   1387  C CG   . LYS A 1 233 ? 125.133 101.205 137.219 1.00 24.03  ?  233 LYS A CG   1 
ATOM   1388  C CD   . LYS A 1 233 ? 125.249 100.439 135.905 1.00 24.03  ?  233 LYS A CD   1 
ATOM   1389  C CE   . LYS A 1 233 ? 126.552 99.664  135.821 1.00 24.03  ?  233 LYS A CE   1 
ATOM   1390  N NZ   . LYS A 1 233 ? 126.702 98.960  134.518 1.00 24.03  1  233 LYS A NZ   1 
ATOM   1391  H H    . LYS A 1 233 ? 124.949 104.387 137.427 1.00 24.03  ?  233 LYS A H    1 
ATOM   1392  H HA   . LYS A 1 233 ? 124.099 102.848 135.368 1.00 24.03  ?  233 LYS A HA   1 
ATOM   1393  H HB2  . LYS A 1 233 ? 123.821 102.461 138.149 1.00 24.03  ?  233 LYS A HB2  1 
ATOM   1394  H HB3  . LYS A 1 233 ? 123.120 101.511 137.090 1.00 24.03  ?  233 LYS A HB3  1 
ATOM   1395  H HG2  . LYS A 1 233 ? 125.919 101.764 137.315 1.00 24.03  ?  233 LYS A HG2  1 
ATOM   1396  H HG3  . LYS A 1 233 ? 125.092 100.560 137.942 1.00 24.03  ?  233 LYS A HG3  1 
ATOM   1397  H HD2  . LYS A 1 233 ? 124.516 99.807  135.838 1.00 24.03  ?  233 LYS A HD2  1 
ATOM   1398  H HD3  . LYS A 1 233 ? 125.227 101.059 135.161 1.00 24.03  ?  233 LYS A HD3  1 
ATOM   1399  H HE2  . LYS A 1 233 ? 127.297 100.278 135.922 1.00 24.03  ?  233 LYS A HE2  1 
ATOM   1400  H HE3  . LYS A 1 233 ? 126.570 98.997  136.524 1.00 24.03  ?  233 LYS A HE3  1 
ATOM   1401  H HZ1  . LYS A 1 233 ? 127.473 98.517  134.499 1.00 24.03  ?  233 LYS A HZ1  1 
ATOM   1402  H HZ2  . LYS A 1 233 ? 126.034 98.383  134.406 1.00 24.03  ?  233 LYS A HZ2  1 
ATOM   1403  H HZ3  . LYS A 1 233 ? 126.690 99.549  133.851 1.00 24.03  ?  233 LYS A HZ3  1 
ATOM   1404  N N    . TRP A 1 234 ? 122.005 104.473 137.193 1.00 21.80  ?  234 TRP A N    1 
ATOM   1405  C CA   . TRP A 1 234 ? 120.642 104.991 137.172 1.00 21.80  ?  234 TRP A CA   1 
ATOM   1406  C C    . TRP A 1 234 ? 120.494 106.215 136.277 1.00 21.80  ?  234 TRP A C    1 
ATOM   1407  O O    . TRP A 1 234 ? 119.364 106.588 135.946 1.00 21.80  ?  234 TRP A O    1 
ATOM   1408  C CB   . TRP A 1 234 ? 120.176 105.318 138.594 1.00 21.80  ?  234 TRP A CB   1 
ATOM   1409  C CG   . TRP A 1 234 ? 120.984 106.367 139.298 1.00 21.80  ?  234 TRP A CG   1 
ATOM   1410  C CD1  . TRP A 1 234 ? 121.937 106.161 140.252 1.00 21.80  ?  234 TRP A CD1  1 
ATOM   1411  C CD2  . TRP A 1 234 ? 120.900 107.787 139.117 1.00 21.80  ?  234 TRP A CD2  1 
ATOM   1412  N NE1  . TRP A 1 234 ? 122.454 107.361 140.673 1.00 21.80  ?  234 TRP A NE1  1 
ATOM   1413  C CE2  . TRP A 1 234 ? 121.836 108.375 139.991 1.00 21.80  ?  234 TRP A CE2  1 
ATOM   1414  C CE3  . TRP A 1 234 ? 120.127 108.618 138.300 1.00 21.80  ?  234 TRP A CE3  1 
ATOM   1415  C CZ2  . TRP A 1 234 ? 122.020 109.754 140.069 1.00 21.80  ?  234 TRP A CZ2  1 
ATOM   1416  C CZ3  . TRP A 1 234 ? 120.313 109.986 138.379 1.00 21.80  ?  234 TRP A CZ3  1 
ATOM   1417  C CH2  . TRP A 1 234 ? 121.251 110.540 139.257 1.00 21.80  ?  234 TRP A CH2  1 
ATOM   1418  H H    . TRP A 1 234 ? 122.437 104.618 137.922 1.00 21.80  ?  234 TRP A H    1 
ATOM   1419  H HA   . TRP A 1 234 ? 120.056 104.301 136.823 1.00 21.80  ?  234 TRP A HA   1 
ATOM   1420  H HB2  . TRP A 1 234 ? 119.260 105.633 138.554 1.00 21.80  ?  234 TRP A HB2  1 
ATOM   1421  H HB3  . TRP A 1 234 ? 120.218 104.508 139.127 1.00 21.80  ?  234 TRP A HB3  1 
ATOM   1422  H HD1  . TRP A 1 234 ? 122.198 105.327 140.572 1.00 21.80  ?  234 TRP A HD1  1 
ATOM   1423  H HE1  . TRP A 1 234 ? 123.069 107.460 141.267 1.00 21.80  ?  234 TRP A HE1  1 
ATOM   1424  H HE3  . TRP A 1 234 ? 119.502 108.257 137.713 1.00 21.80  ?  234 TRP A HE3  1 
ATOM   1425  H HZ2  . TRP A 1 234 ? 122.643 110.125 140.652 1.00 21.80  ?  234 TRP A HZ2  1 
ATOM   1426  H HZ3  . TRP A 1 234 ? 119.804 110.548 137.840 1.00 21.80  ?  234 TRP A HZ3  1 
ATOM   1427  H HH2  . TRP A 1 234 ? 121.354 111.464 139.289 1.00 21.80  ?  234 TRP A HH2  1 
ATOM   1428  N N    . ILE A 1 235 ? 121.599 106.849 135.880 1.00 21.41  ?  235 ILE A N    1 
ATOM   1429  C CA   . ILE A 1 235 ? 121.503 107.989 134.974 1.00 21.41  ?  235 ILE A CA   1 
ATOM   1430  C C    . ILE A 1 235 ? 121.016 107.546 133.600 1.00 21.41  ?  235 ILE A C    1 
ATOM   1431  O O    . ILE A 1 235 ? 120.394 108.330 132.873 1.00 21.41  ?  235 ILE A O    1 
ATOM   1432  C CB   . ILE A 1 235 ? 122.858 108.717 134.882 1.00 21.41  ?  235 ILE A CB   1 
ATOM   1433  C CG1  . ILE A 1 235 ? 122.679 110.115 134.285 1.00 21.41  ?  235 ILE A CG1  1 
ATOM   1434  C CG2  . ILE A 1 235 ? 123.845 107.908 134.052 1.00 21.41  ?  235 ILE A CG2  1 
ATOM   1435  C CD1  . ILE A 1 235 ? 121.955 111.085 135.194 1.00 21.41  ?  235 ILE A CD1  1 
ATOM   1436  H H    . ILE A 1 235 ? 122.400 106.643 136.116 1.00 21.41  ?  235 ILE A H    1 
ATOM   1437  H HA   . ILE A 1 235 ? 120.851 108.612 135.331 1.00 21.41  ?  235 ILE A HA   1 
ATOM   1438  H HB   . ILE A 1 235 ? 123.213 108.816 135.778 1.00 21.41  ?  235 ILE A HB   1 
ATOM   1439  H HG12 . ILE A 1 235 ? 123.555 110.486 134.095 1.00 21.41  ?  235 ILE A HG12 1 
ATOM   1440  H HG13 . ILE A 1 235 ? 122.170 110.042 133.463 1.00 21.41  ?  235 ILE A HG13 1 
ATOM   1441  H HG21 . ILE A 1 235 ? 123.775 106.973 134.302 1.00 21.41  ?  235 ILE A HG21 1 
ATOM   1442  H HG22 . ILE A 1 235 ? 124.742 108.231 134.227 1.00 21.41  ?  235 ILE A HG22 1 
ATOM   1443  H HG23 . ILE A 1 235 ? 123.632 108.015 133.111 1.00 21.41  ?  235 ILE A HG23 1 
ATOM   1444  H HD11 . ILE A 1 235 ? 122.039 111.981 134.830 1.00 21.41  ?  235 ILE A HD11 1 
ATOM   1445  H HD12 . ILE A 1 235 ? 122.355 111.048 136.077 1.00 21.41  ?  235 ILE A HD12 1 
ATOM   1446  H HD13 . ILE A 1 235 ? 121.019 110.836 135.244 1.00 21.41  ?  235 ILE A HD13 1 
ATOM   1447  N N    . GLN A 1 236 ? 121.288 106.296 133.218 1.00 20.32  ?  236 GLN A N    1 
ATOM   1448  C CA   . GLN A 1 236 ? 120.881 105.819 131.901 1.00 20.32  ?  236 GLN A CA   1 
ATOM   1449  C C    . GLN A 1 236 ? 119.368 105.860 131.729 1.00 20.32  ?  236 GLN A C    1 
ATOM   1450  O O    . GLN A 1 236 ? 118.875 105.946 130.598 1.00 20.32  ?  236 GLN A O    1 
ATOM   1451  C CB   . GLN A 1 236 ? 121.396 104.397 131.679 1.00 20.32  ?  236 GLN A CB   1 
ATOM   1452  C CG   . GLN A 1 236 ? 122.905 104.258 131.787 1.00 20.32  ?  236 GLN A CG   1 
ATOM   1453  C CD   . GLN A 1 236 ? 123.378 102.838 131.549 1.00 20.32  ?  236 GLN A CD   1 
ATOM   1454  O OE1  . GLN A 1 236 ? 122.650 102.014 130.996 1.00 20.32  ?  236 GLN A OE1  1 
ATOM   1455  N NE2  . GLN A 1 236 ? 124.604 102.545 131.965 1.00 20.32  ?  236 GLN A NE2  1 
ATOM   1456  H H    . GLN A 1 236 ? 121.701 105.714 133.698 1.00 20.32  ?  236 GLN A H    1 
ATOM   1457  H HA   . GLN A 1 236 ? 121.275 106.390 131.223 1.00 20.32  ?  236 GLN A HA   1 
ATOM   1458  H HB2  . GLN A 1 236 ? 120.997 103.813 132.343 1.00 20.32  ?  236 GLN A HB2  1 
ATOM   1459  H HB3  . GLN A 1 236 ? 121.136 104.107 130.790 1.00 20.32  ?  236 GLN A HB3  1 
ATOM   1460  H HG2  . GLN A 1 236 ? 123.324 104.830 131.125 1.00 20.32  ?  236 GLN A HG2  1 
ATOM   1461  H HG3  . GLN A 1 236 ? 123.185 104.522 132.678 1.00 20.32  ?  236 GLN A HG3  1 
ATOM   1462  H HE21 . GLN A 1 236 ? 125.084 103.148 132.347 1.00 20.32  ?  236 GLN A HE21 1 
ATOM   1463  H HE22 . GLN A 1 236 ? 124.918 101.752 131.853 1.00 20.32  ?  236 GLN A HE22 1 
ATOM   1464  N N    . CYS A 1 237 ? 118.616 105.799 132.830 1.00 21.15  ?  237 CYS A N    1 
ATOM   1465  C CA   . CYS A 1 237 ? 117.161 105.794 132.730 1.00 21.15  ?  237 CYS A CA   1 
ATOM   1466  C C    . CYS A 1 237 ? 116.631 107.087 132.126 1.00 21.15  ?  237 CYS A C    1 
ATOM   1467  O O    . CYS A 1 237 ? 115.556 107.090 131.514 1.00 21.15  ?  237 CYS A O    1 
ATOM   1468  C CB   . CYS A 1 237 ? 116.544 105.566 134.111 1.00 21.15  ?  237 CYS A CB   1 
ATOM   1469  S SG   . CYS A 1 237 ? 117.118 104.068 134.943 1.00 21.15  ?  237 CYS A SG   1 
ATOM   1470  H H    . CYS A 1 237 ? 118.920 105.760 133.633 1.00 21.15  ?  237 CYS A H    1 
ATOM   1471  H HA   . CYS A 1 237 ? 116.887 105.061 132.156 1.00 21.15  ?  237 CYS A HA   1 
ATOM   1472  H HB2  . CYS A 1 237 ? 116.764 106.322 134.678 1.00 21.15  ?  237 CYS A HB2  1 
ATOM   1473  H HB3  . CYS A 1 237 ? 115.581 105.499 134.014 1.00 21.15  ?  237 CYS A HB3  1 
ATOM   1474  H HG   . CYS A 1 237 ? 118.307 104.136 135.095 1.00 21.15  ?  237 CYS A HG   1 
ATOM   1475  N N    . PHE A 1 238 ? 117.364 108.190 132.279 1.00 20.85  ?  238 PHE A N    1 
ATOM   1476  C CA   . PHE A 1 238 ? 116.925 109.498 131.812 1.00 20.85  ?  238 PHE A CA   1 
ATOM   1477  C C    . PHE A 1 238 ? 117.442 109.823 130.414 1.00 20.85  ?  238 PHE A C    1 
ATOM   1478  O O    . PHE A 1 238 ? 117.631 111.000 130.089 1.00 20.85  ?  238 PHE A O    1 
ATOM   1479  C CB   . PHE A 1 238 ? 117.366 110.579 132.799 1.00 20.85  ?  238 PHE A CB   1 
ATOM   1480  C CG   . PHE A 1 238 ? 116.860 110.365 134.196 1.00 20.85  ?  238 PHE A CG   1 
ATOM   1481  C CD1  . PHE A 1 238 ? 115.608 110.822 134.571 1.00 20.85  ?  238 PHE A CD1  1 
ATOM   1482  C CD2  . PHE A 1 238 ? 117.636 109.706 135.134 1.00 20.85  ?  238 PHE A CD2  1 
ATOM   1483  C CE1  . PHE A 1 238 ? 115.140 110.626 135.856 1.00 20.85  ?  238 PHE A CE1  1 
ATOM   1484  C CE2  . PHE A 1 238 ? 117.173 109.507 136.420 1.00 20.85  ?  238 PHE A CE2  1 
ATOM   1485  C CZ   . PHE A 1 238 ? 115.924 109.968 136.781 1.00 20.85  ?  238 PHE A CZ   1 
ATOM   1486  H H    . PHE A 1 238 ? 118.134 108.204 132.660 1.00 20.85  ?  238 PHE A H    1 
ATOM   1487  H HA   . PHE A 1 238 ? 115.956 109.508 131.777 1.00 20.85  ?  238 PHE A HA   1 
ATOM   1488  H HB2  . PHE A 1 238 ? 118.335 110.595 132.833 1.00 20.85  ?  238 PHE A HB2  1 
ATOM   1489  H HB3  . PHE A 1 238 ? 117.034 111.438 132.492 1.00 20.85  ?  238 PHE A HB3  1 
ATOM   1490  H HD1  . PHE A 1 238 ? 115.076 111.266 133.951 1.00 20.85  ?  238 PHE A HD1  1 
ATOM   1491  H HD2  . PHE A 1 238 ? 118.479 109.394 134.896 1.00 20.85  ?  238 PHE A HD2  1 
ATOM   1492  H HE1  . PHE A 1 238 ? 114.297 110.937 136.097 1.00 20.85  ?  238 PHE A HE1  1 
ATOM   1493  H HE2  . PHE A 1 238 ? 117.703 109.064 137.042 1.00 20.85  ?  238 PHE A HE2  1 
ATOM   1494  H HZ   . PHE A 1 238 ? 115.610 109.835 137.647 1.00 20.85  ?  238 PHE A HZ   1 
ATOM   1495  N N    . ASN A 1 239 ? 117.673 108.807 129.582 1.00 20.02  ?  239 ASN A N    1 
ATOM   1496  C CA   . ASN A 1 239 ? 118.164 109.039 128.230 1.00 20.02  ?  239 ASN A CA   1 
ATOM   1497  C C    . ASN A 1 239 ? 117.095 109.593 127.297 1.00 20.02  ?  239 ASN A C    1 
ATOM   1498  O O    . ASN A 1 239 ? 117.436 110.045 126.199 1.00 20.02  ?  239 ASN A O    1 
ATOM   1499  C CB   . ASN A 1 239 ? 118.723 107.740 127.648 1.00 20.02  ?  239 ASN A CB   1 
ATOM   1500  C CG   . ASN A 1 239 ? 117.640 106.844 127.080 1.00 20.02  ?  239 ASN A CG   1 
ATOM   1501  O OD1  . ASN A 1 239 ? 116.612 106.615 127.715 1.00 20.02  ?  239 ASN A OD1  1 
ATOM   1502  N ND2  . ASN A 1 239 ? 117.866 106.333 125.875 1.00 20.02  ?  239 ASN A ND2  1 
ATOM   1503  H H    . ASN A 1 239 ? 117.554 107.978 129.778 1.00 20.02  ?  239 ASN A H    1 
ATOM   1504  H HA   . ASN A 1 239 ? 118.888 109.683 128.267 1.00 20.02  ?  239 ASN A HA   1 
ATOM   1505  H HB2  . ASN A 1 239 ? 119.341 107.954 126.932 1.00 20.02  ?  239 ASN A HB2  1 
ATOM   1506  H HB3  . ASN A 1 239 ? 119.182 107.250 128.348 1.00 20.02  ?  239 ASN A HB3  1 
ATOM   1507  H HD21 . ASN A 1 239 ? 118.597 106.516 125.461 1.00 20.02  ?  239 ASN A HD21 1 
ATOM   1508  H HD22 . ASN A 1 239 ? 117.282 105.819 125.510 1.00 20.02  ?  239 ASN A HD22 1 
ATOM   1509  N N    . ASP A 1 240 ? 115.822 109.571 127.700 1.00 21.54  ?  240 ASP A N    1 
ATOM   1510  C CA   . ASP A 1 240 ? 114.726 110.033 126.855 1.00 21.54  ?  240 ASP A CA   1 
ATOM   1511  C C    . ASP A 1 240 ? 114.087 111.312 127.386 1.00 21.54  ?  240 ASP A C    1 
ATOM   1512  O O    . ASP A 1 240 ? 113.052 111.743 126.869 1.00 21.54  ?  240 ASP A O    1 
ATOM   1513  C CB   . ASP A 1 240 ? 113.668 108.938 126.709 1.00 21.54  ?  240 ASP A CB   1 
ATOM   1514  C CG   . ASP A 1 240 ? 113.184 108.411 128.047 1.00 21.54  ?  240 ASP A CG   1 
ATOM   1515  O OD1  . ASP A 1 240 ? 113.486 109.041 129.083 1.00 21.54  ?  240 ASP A OD1  1 
ATOM   1516  O OD2  . ASP A 1 240 ? 112.500 107.366 128.063 1.00 21.54  -1 240 ASP A OD2  1 
ATOM   1517  H H    . ASP A 1 240 ? 115.567 109.289 128.471 1.00 21.54  ?  240 ASP A H    1 
ATOM   1518  H HA   . ASP A 1 240 ? 115.071 110.225 125.969 1.00 21.54  ?  240 ASP A HA   1 
ATOM   1519  H HB2  . ASP A 1 240 ? 112.903 109.298 126.234 1.00 21.54  ?  240 ASP A HB2  1 
ATOM   1520  H HB3  . ASP A 1 240 ? 114.047 108.195 126.214 1.00 21.54  ?  240 ASP A HB3  1 
ATOM   1521  N N    . VAL A 1 241 ? 114.680 111.931 128.409 1.00 21.16  ?  241 VAL A N    1 
ATOM   1522  C CA   . VAL A 1 241 ? 114.121 113.170 128.937 1.00 21.16  ?  241 VAL A CA   1 
ATOM   1523  C C    . VAL A 1 241 ? 114.326 114.301 127.933 1.00 21.16  ?  241 VAL A C    1 
ATOM   1524  O O    . VAL A 1 241 ? 115.258 114.298 127.120 1.00 21.16  ?  241 VAL A O    1 
ATOM   1525  C CB   . VAL A 1 241 ? 114.744 113.517 130.299 1.00 21.16  ?  241 VAL A CB   1 
ATOM   1526  C CG1  . VAL A 1 241 ? 114.463 112.413 131.307 1.00 21.16  ?  241 VAL A CG1  1 
ATOM   1527  C CG2  . VAL A 1 241 ? 116.242 113.753 130.162 1.00 21.16  ?  241 VAL A CG2  1 
ATOM   1528  H H    . VAL A 1 241 ? 115.392 111.659 128.808 1.00 21.16  ?  241 VAL A H    1 
ATOM   1529  H HA   . VAL A 1 241 ? 113.167 113.055 129.066 1.00 21.16  ?  241 VAL A HA   1 
ATOM   1530  H HB   . VAL A 1 241 ? 114.341 114.335 130.631 1.00 21.16  ?  241 VAL A HB   1 
ATOM   1531  H HG11 . VAL A 1 241 ? 113.504 112.277 131.366 1.00 21.16  ?  241 VAL A HG11 1 
ATOM   1532  H HG12 . VAL A 1 241 ? 114.814 112.678 132.171 1.00 21.16  ?  241 VAL A HG12 1 
ATOM   1533  H HG13 . VAL A 1 241 ? 114.895 111.597 131.010 1.00 21.16  ?  241 VAL A HG13 1 
ATOM   1534  H HG21 . VAL A 1 241 ? 116.427 114.695 130.303 1.00 21.16  ?  241 VAL A HG21 1 
ATOM   1535  H HG22 . VAL A 1 241 ? 116.527 113.490 129.273 1.00 21.16  ?  241 VAL A HG22 1 
ATOM   1536  H HG23 . VAL A 1 241 ? 116.706 113.221 130.827 1.00 21.16  ?  241 VAL A HG23 1 
ATOM   1537  N N    . THR A 1 242 ? 113.429 115.288 127.994 1.00 22.99  ?  242 THR A N    1 
ATOM   1538  C CA   . THR A 1 242 ? 113.506 116.413 127.068 1.00 22.99  ?  242 THR A CA   1 
ATOM   1539  C C    . THR A 1 242 ? 114.809 117.182 127.250 1.00 22.99  ?  242 THR A C    1 
ATOM   1540  O O    . THR A 1 242 ? 115.477 117.537 126.272 1.00 22.99  ?  242 THR A O    1 
ATOM   1541  C CB   . THR A 1 242 ? 112.304 117.339 127.267 1.00 22.99  ?  242 THR A CB   1 
ATOM   1542  O OG1  . THR A 1 242 ? 111.097 116.634 126.953 1.00 22.99  ?  242 THR A OG1  1 
ATOM   1543  C CG2  . THR A 1 242 ? 112.418 118.568 126.375 1.00 22.99  ?  242 THR A CG2  1 
ATOM   1544  H H    . THR A 1 242 ? 112.778 115.328 128.554 1.00 22.99  ?  242 THR A H    1 
ATOM   1545  H HA   . THR A 1 242 ? 113.480 116.077 126.158 1.00 22.99  ?  242 THR A HA   1 
ATOM   1546  H HB   . THR A 1 242 ? 112.274 117.633 128.191 1.00 22.99  ?  242 THR A HB   1 
ATOM   1547  H HG1  . THR A 1 242 ? 110.433 117.138 127.062 1.00 22.99  ?  242 THR A HG1  1 
ATOM   1548  H HG21 . THR A 1 242 ? 111.559 119.015 126.317 1.00 22.99  ?  242 THR A HG21 1 
ATOM   1549  H HG22 . THR A 1 242 ? 112.697 118.306 125.484 1.00 22.99  ?  242 THR A HG22 1 
ATOM   1550  H HG23 . THR A 1 242 ? 113.070 119.187 126.740 1.00 22.99  ?  242 THR A HG23 1 
ATOM   1551  N N    . ALA A 1 243 ? 115.187 117.448 128.498 1.00 22.10  ?  243 ALA A N    1 
ATOM   1552  C CA   . ALA A 1 243 ? 116.417 118.168 128.787 1.00 22.10  ?  243 ALA A CA   1 
ATOM   1553  C C    . ALA A 1 243 ? 116.860 117.850 130.206 1.00 22.10  ?  243 ALA A C    1 
ATOM   1554  O O    . ALA A 1 243 ? 116.049 117.470 131.055 1.00 22.10  ?  243 ALA A O    1 
ATOM   1555  C CB   . ALA A 1 243 ? 116.239 119.681 128.615 1.00 22.10  ?  243 ALA A CB   1 
ATOM   1556  H H    . ALA A 1 243 ? 114.743 117.220 129.198 1.00 22.10  ?  243 ALA A H    1 
ATOM   1557  H HA   . ALA A 1 243 ? 117.111 117.872 128.178 1.00 22.10  ?  243 ALA A HA   1 
ATOM   1558  H HB1  . ALA A 1 243 ? 117.080 120.122 128.813 1.00 22.10  ?  243 ALA A HB1  1 
ATOM   1559  H HB2  . ALA A 1 243 ? 115.975 119.866 127.700 1.00 22.10  ?  243 ALA A HB2  1 
ATOM   1560  H HB3  . ALA A 1 243 ? 115.552 119.989 129.227 1.00 22.10  ?  243 ALA A HB3  1 
ATOM   1561  N N    . ILE A 1 244 ? 118.156 118.010 130.453 1.00 21.88  ?  244 ILE A N    1 
ATOM   1562  C CA   . ILE A 1 244 ? 118.744 117.811 131.772 1.00 21.88  ?  244 ILE A CA   1 
ATOM   1563  C C    . ILE A 1 244 ? 119.134 119.176 132.320 1.00 21.88  ?  244 ILE A C    1 
ATOM   1564  O O    . ILE A 1 244 ? 119.977 119.870 131.739 1.00 21.88  ?  244 ILE A O    1 
ATOM   1565  C CB   . ILE A 1 244 ? 119.958 116.871 131.711 1.00 21.88  ?  244 ILE A CB   1 
ATOM   1566  C CG1  . ILE A 1 244 ? 119.519 115.467 131.289 1.00 21.88  ?  244 ILE A CG1  1 
ATOM   1567  C CG2  . ILE A 1 244 ? 120.668 116.830 133.060 1.00 21.88  ?  244 ILE A CG2  1 
ATOM   1568  C CD1  . ILE A 1 244 ? 120.666 114.545 130.927 1.00 21.88  ?  244 ILE A CD1  1 
ATOM   1569  H H    . ILE A 1 244 ? 118.730 118.240 129.855 1.00 21.88  ?  244 ILE A H    1 
ATOM   1570  H HA   . ILE A 1 244 ? 118.085 117.420 132.366 1.00 21.88  ?  244 ILE A HA   1 
ATOM   1571  H HB   . ILE A 1 244 ? 120.579 117.212 131.047 1.00 21.88  ?  244 ILE A HB   1 
ATOM   1572  H HG12 . ILE A 1 244 ? 119.031 115.059 132.021 1.00 21.88  ?  244 ILE A HG12 1 
ATOM   1573  H HG13 . ILE A 1 244 ? 118.943 115.540 130.512 1.00 21.88  ?  244 ILE A HG13 1 
ATOM   1574  H HG21 . ILE A 1 244 ? 121.150 117.661 133.192 1.00 21.88  ?  244 ILE A HG21 1 
ATOM   1575  H HG22 . ILE A 1 244 ? 121.290 116.087 133.071 1.00 21.88  ?  244 ILE A HG22 1 
ATOM   1576  H HG23 . ILE A 1 244 ? 120.006 116.716 133.760 1.00 21.88  ?  244 ILE A HG23 1 
ATOM   1577  H HD11 . ILE A 1 244 ? 120.307 113.749 130.505 1.00 21.88  ?  244 ILE A HD11 1 
ATOM   1578  H HD12 . ILE A 1 244 ? 121.146 114.303 131.734 1.00 21.88  ?  244 ILE A HD12 1 
ATOM   1579  H HD13 . ILE A 1 244 ? 121.258 115.005 130.312 1.00 21.88  ?  244 ILE A HD13 1 
ATOM   1580  N N    . ILE A 1 245 ? 118.525 119.563 133.437 1.00 24.56  ?  245 ILE A N    1 
ATOM   1581  C CA   . ILE A 1 245 ? 118.806 120.844 134.074 1.00 24.56  ?  245 ILE A CA   1 
ATOM   1582  C C    . ILE A 1 245 ? 119.991 120.643 135.012 1.00 24.56  ?  245 ILE A C    1 
ATOM   1583  O O    . ILE A 1 245 ? 119.843 120.100 136.109 1.00 24.56  ?  245 ILE A O    1 
ATOM   1584  C CB   . ILE A 1 245 ? 117.583 121.382 134.826 1.00 24.56  ?  245 ILE A CB   1 
ATOM   1585  C CG1  . ILE A 1 245 ? 116.424 121.619 133.855 1.00 24.56  ?  245 ILE A CG1  1 
ATOM   1586  C CG2  . ILE A 1 245 ? 117.935 122.672 135.555 1.00 24.56  ?  245 ILE A CG2  1 
ATOM   1587  C CD1  . ILE A 1 245 ? 115.080 121.782 134.535 1.00 24.56  ?  245 ILE A CD1  1 
ATOM   1588  H H    . ILE A 1 245 ? 117.936 119.093 133.851 1.00 24.56  ?  245 ILE A H    1 
ATOM   1589  H HA   . ILE A 1 245 ? 119.058 121.492 133.398 1.00 24.56  ?  245 ILE A HA   1 
ATOM   1590  H HB   . ILE A 1 245 ? 117.308 120.721 135.481 1.00 24.56  ?  245 ILE A HB   1 
ATOM   1591  H HG12 . ILE A 1 245 ? 116.600 122.429 133.351 1.00 24.56  ?  245 ILE A HG12 1 
ATOM   1592  H HG13 . ILE A 1 245 ? 116.357 120.864 133.251 1.00 24.56  ?  245 ILE A HG13 1 
ATOM   1593  H HG21 . ILE A 1 245 ? 118.504 122.465 136.312 1.00 24.56  ?  245 ILE A HG21 1 
ATOM   1594  H HG22 . ILE A 1 245 ? 118.400 123.263 134.942 1.00 24.56  ?  245 ILE A HG22 1 
ATOM   1595  H HG23 . ILE A 1 245 ? 117.119 123.094 135.865 1.00 24.56  ?  245 ILE A HG23 1 
ATOM   1596  H HD11 . ILE A 1 245 ? 114.386 121.815 133.858 1.00 24.56  ?  245 ILE A HD11 1 
ATOM   1597  H HD12 . ILE A 1 245 ? 114.932 121.026 135.125 1.00 24.56  ?  245 ILE A HD12 1 
ATOM   1598  H HD13 . ILE A 1 245 ? 115.081 122.606 135.047 1.00 24.56  ?  245 ILE A HD13 1 
ATOM   1599  N N    . PHE A 1 246 ? 121.168 121.084 134.579 1.00 26.50  ?  246 PHE A N    1 
ATOM   1600  C CA   . PHE A 1 246 ? 122.392 120.966 135.360 1.00 26.50  ?  246 PHE A CA   1 
ATOM   1601  C C    . PHE A 1 246 ? 122.631 122.281 136.092 1.00 26.50  ?  246 PHE A C    1 
ATOM   1602  O O    . PHE A 1 246 ? 122.913 123.305 135.460 1.00 26.50  ?  246 PHE A O    1 
ATOM   1603  C CB   . PHE A 1 246 ? 123.577 120.621 134.458 1.00 26.50  ?  246 PHE A CB   1 
ATOM   1604  C CG   . PHE A 1 246 ? 124.844 120.319 135.207 1.00 26.50  ?  246 PHE A CG   1 
ATOM   1605  C CD1  . PHE A 1 246 ? 125.728 121.331 135.538 1.00 26.50  ?  246 PHE A CD1  1 
ATOM   1606  C CD2  . PHE A 1 246 ? 125.151 119.020 135.577 1.00 26.50  ?  246 PHE A CD2  1 
ATOM   1607  C CE1  . PHE A 1 246 ? 126.894 121.053 136.225 1.00 26.50  ?  246 PHE A CE1  1 
ATOM   1608  C CE2  . PHE A 1 246 ? 126.315 118.737 136.264 1.00 26.50  ?  246 PHE A CE2  1 
ATOM   1609  C CZ   . PHE A 1 246 ? 127.188 119.755 136.588 1.00 26.50  ?  246 PHE A CZ   1 
ATOM   1610  H H    . PHE A 1 246 ? 121.285 121.464 133.816 1.00 26.50  ?  246 PHE A H    1 
ATOM   1611  H HA   . PHE A 1 246 ? 122.291 120.261 136.019 1.00 26.50  ?  246 PHE A HA   1 
ATOM   1612  H HB2  . PHE A 1 246 ? 123.350 119.838 133.932 1.00 26.50  ?  246 PHE A HB2  1 
ATOM   1613  H HB3  . PHE A 1 246 ? 123.752 121.372 133.871 1.00 26.50  ?  246 PHE A HB3  1 
ATOM   1614  H HD1  . PHE A 1 246 ? 125.535 122.208 135.295 1.00 26.50  ?  246 PHE A HD1  1 
ATOM   1615  H HD2  . PHE A 1 246 ? 124.566 118.330 135.361 1.00 26.50  ?  246 PHE A HD2  1 
ATOM   1616  H HE1  . PHE A 1 246 ? 127.481 121.741 136.442 1.00 26.50  ?  246 PHE A HE1  1 
ATOM   1617  H HE2  . PHE A 1 246 ? 126.510 117.861 136.508 1.00 26.50  ?  246 PHE A HE2  1 
ATOM   1618  H HZ   . PHE A 1 246 ? 127.972 119.567 137.051 1.00 26.50  ?  246 PHE A HZ   1 
ATOM   1619  N N    . VAL A 1 247 ? 122.520 122.250 137.417 1.00 30.15  ?  247 VAL A N    1 
ATOM   1620  C CA   . VAL A 1 247 ? 122.655 123.436 138.256 1.00 30.15  ?  247 VAL A CA   1 
ATOM   1621  C C    . VAL A 1 247 ? 124.019 123.383 138.927 1.00 30.15  ?  247 VAL A C    1 
ATOM   1622  O O    . VAL A 1 247 ? 124.318 122.441 139.671 1.00 30.15  ?  247 VAL A O    1 
ATOM   1623  C CB   . VAL A 1 247 ? 121.530 123.523 139.298 1.00 30.15  ?  247 VAL A CB   1 
ATOM   1624  C CG1  . VAL A 1 247 ? 121.632 124.823 140.085 1.00 30.15  ?  247 VAL A CG1  1 
ATOM   1625  C CG2  . VAL A 1 247 ? 120.170 123.406 138.625 1.00 30.15  ?  247 VAL A CG2  1 
ATOM   1626  H H    . VAL A 1 247 ? 122.362 121.533 137.864 1.00 30.15  ?  247 VAL A H    1 
ATOM   1627  H HA   . VAL A 1 247 ? 122.618 124.230 137.701 1.00 30.15  ?  247 VAL A HA   1 
ATOM   1628  H HB   . VAL A 1 247 ? 121.620 122.787 139.923 1.00 30.15  ?  247 VAL A HB   1 
ATOM   1629  H HG11 . VAL A 1 247 ? 120.854 124.906 140.657 1.00 30.15  ?  247 VAL A HG11 1 
ATOM   1630  H HG12 . VAL A 1 247 ? 122.438 124.805 140.624 1.00 30.15  ?  247 VAL A HG12 1 
ATOM   1631  H HG13 . VAL A 1 247 ? 121.666 125.566 139.462 1.00 30.15  ?  247 VAL A HG13 1 
ATOM   1632  H HG21 . VAL A 1 247 ? 119.477 123.560 139.286 1.00 30.15  ?  247 VAL A HG21 1 
ATOM   1633  H HG22 . VAL A 1 247 ? 120.109 124.070 137.921 1.00 30.15  ?  247 VAL A HG22 1 
ATOM   1634  H HG23 . VAL A 1 247 ? 120.078 122.516 138.250 1.00 30.15  ?  247 VAL A HG23 1 
ATOM   1635  N N    . VAL A 1 248 ? 124.845 124.392 138.663 1.00 32.32  ?  248 VAL A N    1 
ATOM   1636  C CA   . VAL A 1 248 ? 126.187 124.490 139.222 1.00 32.32  ?  248 VAL A CA   1 
ATOM   1637  C C    . VAL A 1 248 ? 126.350 125.873 139.835 1.00 32.32  ?  248 VAL A C    1 
ATOM   1638  O O    . VAL A 1 248 ? 126.014 126.881 139.204 1.00 32.32  ?  248 VAL A O    1 
ATOM   1639  C CB   . VAL A 1 248 ? 127.272 124.239 138.156 1.00 32.32  ?  248 VAL A CB   1 
ATOM   1640  C CG1  . VAL A 1 248 ? 127.095 125.185 136.974 1.00 32.32  ?  248 VAL A CG1  1 
ATOM   1641  C CG2  . VAL A 1 248 ? 128.659 124.390 138.765 1.00 32.32  ?  248 VAL A CG2  1 
ATOM   1642  H H    . VAL A 1 248 ? 124.642 125.051 138.149 1.00 32.32  ?  248 VAL A H    1 
ATOM   1643  H HA   . VAL A 1 248 ? 126.293 123.831 139.925 1.00 32.32  ?  248 VAL A HA   1 
ATOM   1644  H HB   . VAL A 1 248 ? 127.187 123.331 137.829 1.00 32.32  ?  248 VAL A HB   1 
ATOM   1645  H HG11 . VAL A 1 248 ? 126.191 125.104 136.633 1.00 32.32  ?  248 VAL A HG11 1 
ATOM   1646  H HG12 . VAL A 1 248 ? 127.730 124.942 136.282 1.00 32.32  ?  248 VAL A HG12 1 
ATOM   1647  H HG13 . VAL A 1 248 ? 127.260 126.094 137.266 1.00 32.32  ?  248 VAL A HG13 1 
ATOM   1648  H HG21 . VAL A 1 248 ? 128.841 125.331 138.913 1.00 32.32  ?  248 VAL A HG21 1 
ATOM   1649  H HG22 . VAL A 1 248 ? 129.313 124.020 138.151 1.00 32.32  ?  248 VAL A HG22 1 
ATOM   1650  H HG23 . VAL A 1 248 ? 128.688 123.909 139.606 1.00 32.32  ?  248 VAL A HG23 1 
ATOM   1651  N N    . ALA A 1 249 ? 126.861 125.919 141.063 1.00 39.36  ?  249 ALA A N    1 
ATOM   1652  C CA   . ALA A 1 249 ? 127.122 127.183 141.742 1.00 39.36  ?  249 ALA A CA   1 
ATOM   1653  C C    . ALA A 1 249 ? 128.456 127.733 141.251 1.00 39.36  ?  249 ALA A C    1 
ATOM   1654  O O    . ALA A 1 249 ? 129.512 127.147 141.510 1.00 39.36  ?  249 ALA A O    1 
ATOM   1655  C CB   . ALA A 1 249 ? 127.127 126.986 143.255 1.00 39.36  ?  249 ALA A CB   1 
ATOM   1656  H H    . ALA A 1 249 ? 127.065 125.225 141.528 1.00 39.36  ?  249 ALA A H    1 
ATOM   1657  H HA   . ALA A 1 249 ? 126.426 127.820 141.518 1.00 39.36  ?  249 ALA A HA   1 
ATOM   1658  H HB1  . ALA A 1 249 ? 127.375 127.820 143.682 1.00 39.36  ?  249 ALA A HB1  1 
ATOM   1659  H HB2  . ALA A 1 249 ? 127.768 126.294 143.479 1.00 39.36  ?  249 ALA A HB2  1 
ATOM   1660  H HB3  . ALA A 1 249 ? 126.240 126.716 143.540 1.00 39.36  ?  249 ALA A HB3  1 
ATOM   1661  N N    . SER A 1 250 ? 128.409 128.862 140.539 1.00 41.67  ?  250 SER A N    1 
ATOM   1662  C CA   . SER A 1 250 ? 129.632 129.444 139.997 1.00 41.67  ?  250 SER A CA   1 
ATOM   1663  C C    . SER A 1 250 ? 130.597 129.832 141.110 1.00 41.67  ?  250 SER A C    1 
ATOM   1664  O O    . SER A 1 250 ? 131.809 129.615 140.996 1.00 41.67  ?  250 SER A O    1 
ATOM   1665  C CB   . SER A 1 250 ? 129.294 130.658 139.133 1.00 41.67  ?  250 SER A CB   1 
ATOM   1666  O OG   . SER A 1 250 ? 128.571 131.625 139.874 1.00 41.67  ?  250 SER A OG   1 
ATOM   1667  H H    . SER A 1 250 ? 127.692 129.302 140.360 1.00 41.67  ?  250 SER A H    1 
ATOM   1668  H HA   . SER A 1 250 ? 130.072 128.788 139.434 1.00 41.67  ?  250 SER A HA   1 
ATOM   1669  H HB2  . SER A 1 250 ? 130.118 131.057 138.813 1.00 41.67  ?  250 SER A HB2  1 
ATOM   1670  H HB3  . SER A 1 250 ? 128.753 130.369 138.381 1.00 41.67  ?  250 SER A HB3  1 
ATOM   1671  H HG   . SER A 1 250 ? 127.851 131.295 140.154 1.00 41.67  ?  250 SER A HG   1 
ATOM   1672  N N    . SER A 1 251 ? 130.079 130.408 142.194 1.00 45.41  ?  251 SER A N    1 
ATOM   1673  C CA   . SER A 1 251 ? 130.914 130.821 143.314 1.00 45.41  ?  251 SER A CA   1 
ATOM   1674  C C    . SER A 1 251 ? 131.239 129.634 144.210 1.00 45.41  ?  251 SER A C    1 
ATOM   1675  O O    . SER A 1 251 ? 130.886 129.629 145.394 1.00 45.41  ?  251 SER A O    1 
ATOM   1676  C CB   . SER A 1 251 ? 130.215 131.913 144.124 1.00 45.41  ?  251 SER A CB   1 
ATOM   1677  O OG   . SER A 1 251 ? 129.234 131.353 144.979 1.00 45.41  ?  251 SER A OG   1 
ATOM   1678  H H    . SER A 1 251 ? 129.242 130.570 142.303 1.00 45.41  ?  251 SER A H    1 
ATOM   1679  H HA   . SER A 1 251 ? 131.748 131.183 142.975 1.00 45.41  ?  251 SER A HA   1 
ATOM   1680  H HB2  . SER A 1 251 ? 130.873 132.381 144.660 1.00 45.41  ?  251 SER A HB2  1 
ATOM   1681  H HB3  . SER A 1 251 ? 129.784 132.529 143.513 1.00 45.41  ?  251 SER A HB3  1 
ATOM   1682  H HG   . SER A 1 251 ? 128.653 130.950 144.524 1.00 45.41  ?  251 SER A HG   1 
ATOM   1683  N N    . SER A 1 252 ? 131.913 128.622 143.654 1.00 46.15  ?  252 SER A N    1 
ATOM   1684  C CA   . SER A 1 252 ? 132.255 127.431 144.422 1.00 46.15  ?  252 SER A CA   1 
ATOM   1685  C C    . SER A 1 252 ? 133.751 127.133 144.387 1.00 46.15  ?  252 SER A C    1 
ATOM   1686  O O    . SER A 1 252 ? 134.199 126.182 145.040 1.00 46.15  ?  252 SER A O    1 
ATOM   1687  C CB   . SER A 1 252 ? 131.477 126.217 143.906 1.00 46.15  ?  252 SER A CB   1 
ATOM   1688  O OG   . SER A 1 252 ? 130.093 126.348 144.174 1.00 46.15  ?  252 SER A OG   1 
ATOM   1689  H H    . SER A 1 252 ? 132.183 128.606 142.838 1.00 46.15  ?  252 SER A H    1 
ATOM   1690  H HA   . SER A 1 252 ? 132.006 127.567 145.349 1.00 46.15  ?  252 SER A HA   1 
ATOM   1691  H HB2  . SER A 1 252 ? 131.608 126.139 142.948 1.00 46.15  ?  252 SER A HB2  1 
ATOM   1692  H HB3  . SER A 1 252 ? 131.807 125.423 144.351 1.00 46.15  ?  252 SER A HB3  1 
ATOM   1693  H HG   . SER A 1 252 ? 129.693 125.637 143.971 1.00 46.15  ?  252 SER A HG   1 
ATOM   1694  N N    . TYR A 1 253 ? 134.534 127.914 143.648 1.00 51.03  ?  253 TYR A N    1 
ATOM   1695  C CA   . TYR A 1 253 ? 135.975 127.717 143.631 1.00 51.03  ?  253 TYR A CA   1 
ATOM   1696  C C    . TYR A 1 253 ? 136.573 128.086 144.984 1.00 51.03  ?  253 TYR A C    1 
ATOM   1697  O O    . TYR A 1 253 ? 136.245 129.119 145.574 1.00 51.03  ?  253 TYR A O    1 
ATOM   1698  C CB   . TYR A 1 253 ? 136.629 128.555 142.527 1.00 51.03  ?  253 TYR A CB   1 
ATOM   1699  C CG   . TYR A 1 253 ? 136.495 130.056 142.700 1.00 51.03  ?  253 TYR A CG   1 
ATOM   1700  C CD1  . TYR A 1 253 ? 135.274 130.695 142.530 1.00 51.03  ?  253 TYR A CD1  1 
ATOM   1701  C CD2  . TYR A 1 253 ? 137.601 130.835 143.014 1.00 51.03  ?  253 TYR A CD2  1 
ATOM   1702  C CE1  . TYR A 1 253 ? 135.155 132.063 142.683 1.00 51.03  ?  253 TYR A CE1  1 
ATOM   1703  C CE2  . TYR A 1 253 ? 137.491 132.204 143.170 1.00 51.03  ?  253 TYR A CE2  1 
ATOM   1704  C CZ   . TYR A 1 253 ? 136.266 132.812 143.001 1.00 51.03  ?  253 TYR A CZ   1 
ATOM   1705  O OH   . TYR A 1 253 ? 136.151 134.175 143.153 1.00 51.03  ?  253 TYR A OH   1 
ATOM   1706  H H    . TYR A 1 253 ? 134.251 128.549 143.147 1.00 51.03  ?  253 TYR A H    1 
ATOM   1707  H HA   . TYR A 1 253 ? 136.168 126.783 143.457 1.00 51.03  ?  253 TYR A HA   1 
ATOM   1708  H HB2  . TYR A 1 253 ? 137.576 128.345 142.500 1.00 51.03  ?  253 TYR A HB2  1 
ATOM   1709  H HB3  . TYR A 1 253 ? 136.219 128.321 141.680 1.00 51.03  ?  253 TYR A HB3  1 
ATOM   1710  H HD1  . TYR A 1 253 ? 134.520 130.195 142.316 1.00 51.03  ?  253 TYR A HD1  1 
ATOM   1711  H HD2  . TYR A 1 253 ? 138.429 130.427 143.130 1.00 51.03  ?  253 TYR A HD2  1 
ATOM   1712  H HE1  . TYR A 1 253 ? 134.329 132.476 142.569 1.00 51.03  ?  253 TYR A HE1  1 
ATOM   1713  H HE2  . TYR A 1 253 ? 138.240 132.711 143.384 1.00 51.03  ?  253 TYR A HE2  1 
ATOM   1714  H HH   . TYR A 1 253 ? 135.366 134.417 142.977 1.00 51.03  ?  253 TYR A HH   1 
ATOM   1715  N N    . ASN A 1 254 ? 137.455 127.222 145.476 1.00 53.40  ?  254 ASN A N    1 
ATOM   1716  C CA   . ASN A 1 254 ? 138.071 127.417 146.784 1.00 53.40  ?  254 ASN A CA   1 
ATOM   1717  C C    . ASN A 1 254 ? 138.815 128.747 146.843 1.00 53.40  ?  254 ASN A C    1 
ATOM   1718  O O    . ASN A 1 254 ? 138.249 129.769 147.230 1.00 53.40  ?  254 ASN A O    1 
ATOM   1719  C CB   . ASN A 1 254 ? 139.027 126.265 147.100 1.00 53.40  ?  254 ASN A CB   1 
ATOM   1720  C CG   . ASN A 1 254 ? 139.426 126.222 148.562 1.00 53.40  ?  254 ASN A CG   1 
ATOM   1721  O OD1  . ASN A 1 254 ? 139.218 127.183 149.304 1.00 53.40  ?  254 ASN A OD1  1 
ATOM   1722  N ND2  . ASN A 1 254 ? 140.002 125.103 148.985 1.00 53.40  ?  254 ASN A ND2  1 
ATOM   1723  H H    . ASN A 1 254 ? 137.716 126.511 145.070 1.00 53.40  ?  254 ASN A H    1 
ATOM   1724  H HA   . ASN A 1 254 ? 137.378 127.429 147.462 1.00 53.40  ?  254 ASN A HA   1 
ATOM   1725  H HB2  . ASN A 1 254 ? 138.592 125.425 146.883 1.00 53.40  ?  254 ASN A HB2  1 
ATOM   1726  H HB3  . ASN A 1 254 ? 139.833 126.369 146.572 1.00 53.40  ?  254 ASN A HB3  1 
ATOM   1727  H HD21 . ASN A 1 254 ? 140.131 124.452 148.438 1.00 53.40  ?  254 ASN A HD21 1 
ATOM   1728  H HD22 . ASN A 1 254 ? 140.247 125.029 149.806 1.00 53.40  ?  254 ASN A HD22 1 
ATOM   1729  N N    . THR A 1 263 ? 136.974 120.976 149.002 1.00 46.34  ?  263 THR A N    1 
ATOM   1730  C CA   . THR A 1 263 ? 137.265 120.531 147.644 1.00 46.34  ?  263 THR A CA   1 
ATOM   1731  C C    . THR A 1 263 ? 136.797 121.562 146.622 1.00 46.34  ?  263 THR A C    1 
ATOM   1732  O O    . THR A 1 263 ? 135.836 122.293 146.860 1.00 46.34  ?  263 THR A O    1 
ATOM   1733  C CB   . THR A 1 263 ? 136.595 119.176 147.338 1.00 46.34  ?  263 THR A CB   1 
ATOM   1734  O OG1  . THR A 1 263 ? 137.030 118.701 146.058 1.00 46.34  ?  263 THR A OG1  1 
ATOM   1735  C CG2  . THR A 1 263 ? 135.077 119.308 147.341 1.00 46.34  ?  263 THR A CG2  1 
ATOM   1736  H H    . THR A 1 263 ? 136.189 121.315 149.098 1.00 46.34  ?  263 THR A H    1 
ATOM   1737  H HA   . THR A 1 263 ? 138.224 120.423 147.545 1.00 46.34  ?  263 THR A HA   1 
ATOM   1738  H HB   . THR A 1 263 ? 136.846 118.533 148.020 1.00 46.34  ?  263 THR A HB   1 
ATOM   1739  H HG1  . THR A 1 263 ? 136.657 117.969 145.881 1.00 46.34  ?  263 THR A HG1  1 
ATOM   1740  H HG21 . THR A 1 263 ? 134.670 118.427 147.355 1.00 46.34  ?  263 THR A HG21 1 
ATOM   1741  H HG22 . THR A 1 263 ? 134.780 119.778 146.547 1.00 46.34  ?  263 THR A HG22 1 
ATOM   1742  H HG23 . THR A 1 263 ? 134.788 119.798 148.127 1.00 46.34  ?  263 THR A HG23 1 
ATOM   1743  N N    . ASN A 1 264 ? 137.483 121.615 145.483 1.00 43.59  ?  264 ASN A N    1 
ATOM   1744  C CA   . ASN A 1 264 ? 137.119 122.527 144.401 1.00 43.59  ?  264 ASN A CA   1 
ATOM   1745  C C    . ASN A 1 264 ? 135.870 121.975 143.728 1.00 43.59  ?  264 ASN A C    1 
ATOM   1746  O O    . ASN A 1 264 ? 135.952 121.145 142.820 1.00 43.59  ?  264 ASN A O    1 
ATOM   1747  C CB   . ASN A 1 264 ? 138.271 122.674 143.412 1.00 43.59  ?  264 ASN A CB   1 
ATOM   1748  C CG   . ASN A 1 264 ? 137.958 123.644 142.287 1.00 43.59  ?  264 ASN A CG   1 
ATOM   1749  O OD1  . ASN A 1 264 ? 136.824 124.100 142.138 1.00 43.59  ?  264 ASN A OD1  1 
ATOM   1750  N ND2  . ASN A 1 264 ? 138.968 123.965 141.487 1.00 43.59  ?  264 ASN A ND2  1 
ATOM   1751  H H    . ASN A 1 264 ? 138.171 121.128 145.311 1.00 43.59  ?  264 ASN A H    1 
ATOM   1752  H HA   . ASN A 1 264 ? 136.913 123.401 144.767 1.00 43.59  ?  264 ASN A HA   1 
ATOM   1753  H HB2  . ASN A 1 264 ? 139.052 123.003 143.884 1.00 43.59  ?  264 ASN A HB2  1 
ATOM   1754  H HB3  . ASN A 1 264 ? 138.461 121.809 143.018 1.00 43.59  ?  264 ASN A HB3  1 
ATOM   1755  H HD21 . ASN A 1 264 ? 139.747 123.626 141.622 1.00 43.59  ?  264 ASN A HD21 1 
ATOM   1756  H HD22 . ASN A 1 264 ? 138.843 124.510 140.834 1.00 43.59  ?  264 ASN A HD22 1 
ATOM   1757  N N    . ARG A 1 265 ? 134.702 122.439 144.176 1.00 44.09  ?  265 ARG A N    1 
ATOM   1758  C CA   . ARG A 1 265 ? 133.449 121.911 143.647 1.00 44.09  ?  265 ARG A CA   1 
ATOM   1759  C C    . ARG A 1 265 ? 133.235 122.307 142.192 1.00 44.09  ?  265 ARG A C    1 
ATOM   1760  O O    . ARG A 1 265 ? 132.517 121.612 141.466 1.00 44.09  ?  265 ARG A O    1 
ATOM   1761  C CB   . ARG A 1 265 ? 132.276 122.390 144.502 1.00 44.09  ?  265 ARG A CB   1 
ATOM   1762  C CG   . ARG A 1 265 ? 132.211 121.750 145.878 1.00 44.09  ?  265 ARG A CG   1 
ATOM   1763  C CD   . ARG A 1 265 ? 130.909 122.089 146.586 1.00 44.09  ?  265 ARG A CD   1 
ATOM   1764  N NE   . ARG A 1 265 ? 130.810 121.448 147.894 1.00 44.09  ?  265 ARG A NE   1 
ATOM   1765  C CZ   . ARG A 1 265 ? 130.555 120.156 148.080 1.00 44.09  ?  265 ARG A CZ   1 
ATOM   1766  N NH1  . ARG A 1 265 ? 130.484 119.665 149.309 1.00 44.09  1  265 ARG A NH1  1 
ATOM   1767  N NH2  . ARG A 1 265 ? 130.369 119.353 147.040 1.00 44.09  ?  265 ARG A NH2  1 
ATOM   1768  H H    . ARG A 1 265 ? 134.610 123.048 144.775 1.00 44.09  ?  265 ARG A H    1 
ATOM   1769  H HA   . ARG A 1 265 ? 133.473 120.943 143.691 1.00 44.09  ?  265 ARG A HA   1 
ATOM   1770  H HB2  . ARG A 1 265 ? 132.356 123.347 144.628 1.00 44.09  ?  265 ARG A HB2  1 
ATOM   1771  H HB3  . ARG A 1 265 ? 131.448 122.187 144.040 1.00 44.09  ?  265 ARG A HB3  1 
ATOM   1772  H HG2  . ARG A 1 265 ? 132.266 120.786 145.786 1.00 44.09  ?  265 ARG A HG2  1 
ATOM   1773  H HG3  . ARG A 1 265 ? 132.946 122.078 146.420 1.00 44.09  ?  265 ARG A HG3  1 
ATOM   1774  H HD2  . ARG A 1 265 ? 130.860 123.049 146.717 1.00 44.09  ?  265 ARG A HD2  1 
ATOM   1775  H HD3  . ARG A 1 265 ? 130.163 121.788 146.043 1.00 44.09  ?  265 ARG A HD3  1 
ATOM   1776  H HE   . ARG A 1 265 ? 130.946 121.934 148.590 1.00 44.09  ?  265 ARG A HE   1 
ATOM   1777  H HH11 . ARG A 1 265 ? 130.604 120.181 149.986 1.00 44.09  ?  265 ARG A HH11 1 
ATOM   1778  H HH12 . ARG A 1 265 ? 130.319 118.829 149.430 1.00 44.09  ?  265 ARG A HH12 1 
ATOM   1779  H HH21 . ARG A 1 265 ? 130.413 119.662 146.239 1.00 44.09  ?  265 ARG A HH21 1 
ATOM   1780  H HH22 . ARG A 1 265 ? 130.204 118.518 147.168 1.00 44.09  ?  265 ARG A HH22 1 
ATOM   1781  N N    . LEU A 1 266 ? 133.834 123.413 141.747 1.00 39.11  ?  266 LEU A N    1 
ATOM   1782  C CA   . LEU A 1 266 ? 133.674 123.820 140.354 1.00 39.11  ?  266 LEU A CA   1 
ATOM   1783  C C    . LEU A 1 266 ? 134.321 122.815 139.409 1.00 39.11  ?  266 LEU A C    1 
ATOM   1784  O O    . LEU A 1 266 ? 133.752 122.482 138.362 1.00 39.11  ?  266 LEU A O    1 
ATOM   1785  C CB   . LEU A 1 266 ? 134.262 125.215 140.144 1.00 39.11  ?  266 LEU A CB   1 
ATOM   1786  C CG   . LEU A 1 266 ? 133.579 126.078 139.078 1.00 39.11  ?  266 LEU A CG   1 
ATOM   1787  C CD1  . LEU A 1 266 ? 132.143 126.402 139.469 1.00 39.11  ?  266 LEU A CD1  1 
ATOM   1788  C CD2  . LEU A 1 266 ? 134.368 127.355 138.839 1.00 39.11  ?  266 LEU A CD2  1 
ATOM   1789  H H    . LEU A 1 266 ? 134.328 123.934 142.221 1.00 39.11  ?  266 LEU A H    1 
ATOM   1790  H HA   . LEU A 1 266 ? 132.727 123.854 140.147 1.00 39.11  ?  266 LEU A HA   1 
ATOM   1791  H HB2  . LEU A 1 266 ? 134.210 125.698 140.983 1.00 39.11  ?  266 LEU A HB2  1 
ATOM   1792  H HB3  . LEU A 1 266 ? 135.192 125.118 139.885 1.00 39.11  ?  266 LEU A HB3  1 
ATOM   1793  H HG   . LEU A 1 266 ? 133.555 125.583 138.244 1.00 39.11  ?  266 LEU A HG   1 
ATOM   1794  H HD11 . LEU A 1 266 ? 131.598 125.606 139.368 1.00 39.11  ?  266 LEU A HD11 1 
ATOM   1795  H HD12 . LEU A 1 266 ? 131.810 127.104 138.888 1.00 39.11  ?  266 LEU A HD12 1 
ATOM   1796  H HD13 . LEU A 1 266 ? 132.127 126.702 140.391 1.00 39.11  ?  266 LEU A HD13 1 
ATOM   1797  H HD21 . LEU A 1 266 ? 133.899 127.898 138.186 1.00 39.11  ?  266 LEU A HD21 1 
ATOM   1798  H HD22 . LEU A 1 266 ? 134.447 127.838 139.676 1.00 39.11  ?  266 LEU A HD22 1 
ATOM   1799  H HD23 . LEU A 1 266 ? 135.248 127.123 138.505 1.00 39.11  ?  266 LEU A HD23 1 
ATOM   1800  N N    . GLN A 1 267 ? 135.511 122.321 139.757 1.00 36.00  ?  267 GLN A N    1 
ATOM   1801  C CA   . GLN A 1 267 ? 136.161 121.313 138.925 1.00 36.00  ?  267 GLN A CA   1 
ATOM   1802  C C    . GLN A 1 267 ? 135.348 120.025 138.893 1.00 36.00  ?  267 GLN A C    1 
ATOM   1803  O O    . GLN A 1 267 ? 135.215 119.390 137.840 1.00 36.00  ?  267 GLN A O    1 
ATOM   1804  C CB   . GLN A 1 267 ? 137.577 121.047 139.440 1.00 36.00  ?  267 GLN A CB   1 
ATOM   1805  C CG   . GLN A 1 267 ? 138.347 119.990 138.659 1.00 36.00  ?  267 GLN A CG   1 
ATOM   1806  C CD   . GLN A 1 267 ? 138.687 120.438 137.251 1.00 36.00  ?  267 GLN A CD   1 
ATOM   1807  O OE1  . GLN A 1 267 ? 139.798 120.894 136.984 1.00 36.00  ?  267 GLN A OE1  1 
ATOM   1808  N NE2  . GLN A 1 267 ? 137.729 120.307 136.341 1.00 36.00  ?  267 GLN A NE2  1 
ATOM   1809  H H    . GLN A 1 267 ? 135.954 122.549 140.458 1.00 36.00  ?  267 GLN A H    1 
ATOM   1810  H HA   . GLN A 1 267 ? 136.229 121.649 138.018 1.00 36.00  ?  267 GLN A HA   1 
ATOM   1811  H HB2  . GLN A 1 267 ? 138.083 121.873 139.395 1.00 36.00  ?  267 GLN A HB2  1 
ATOM   1812  H HB3  . GLN A 1 267 ? 137.521 120.749 140.362 1.00 36.00  ?  267 GLN A HB3  1 
ATOM   1813  H HG2  . GLN A 1 267 ? 139.180 119.806 139.121 1.00 36.00  ?  267 GLN A HG2  1 
ATOM   1814  H HG3  . GLN A 1 267 ? 137.818 119.180 138.600 1.00 36.00  ?  267 GLN A HG3  1 
ATOM   1815  H HE21 . GLN A 1 267 ? 136.964 119.984 136.565 1.00 36.00  ?  267 GLN A HE21 1 
ATOM   1816  H HE22 . GLN A 1 267 ? 137.873 120.547 135.528 1.00 36.00  ?  267 GLN A HE22 1 
ATOM   1817  N N    . ALA A 1 268 ? 134.800 119.621 140.041 1.00 33.75  ?  268 ALA A N    1 
ATOM   1818  C CA   . ALA A 1 268 ? 133.958 118.430 140.076 1.00 33.75  ?  268 ALA A CA   1 
ATOM   1819  C C    . ALA A 1 268 ? 132.716 118.616 139.215 1.00 33.75  ?  268 ALA A C    1 
ATOM   1820  O O    . ALA A 1 268 ? 132.295 117.692 138.511 1.00 33.75  ?  268 ALA A O    1 
ATOM   1821  C CB   . ALA A 1 268 ? 133.568 118.106 141.517 1.00 33.75  ?  268 ALA A CB   1 
ATOM   1822  H H    . ALA A 1 268 ? 134.900 120.012 140.800 1.00 33.75  ?  268 ALA A H    1 
ATOM   1823  H HA   . ALA A 1 268 ? 134.458 117.678 139.723 1.00 33.75  ?  268 ALA A HA   1 
ATOM   1824  H HB1  . ALA A 1 268 ? 133.009 117.313 141.522 1.00 33.75  ?  268 ALA A HB1  1 
ATOM   1825  H HB2  . ALA A 1 268 ? 133.081 118.857 141.889 1.00 33.75  ?  268 ALA A HB2  1 
ATOM   1826  H HB3  . ALA A 1 268 ? 134.374 117.946 142.033 1.00 33.75  ?  268 ALA A HB3  1 
ATOM   1827  N N    . ALA A 1 269 ? 132.112 119.805 139.263 1.00 31.12  ?  269 ALA A N    1 
ATOM   1828  C CA   . ALA A 1 269 ? 130.952 120.081 138.423 1.00 31.12  ?  269 ALA A CA   1 
ATOM   1829  C C    . ALA A 1 269 ? 131.320 120.024 136.946 1.00 31.12  ?  269 ALA A C    1 
ATOM   1830  O O    . ALA A 1 269 ? 130.555 119.500 136.129 1.00 31.12  ?  269 ALA A O    1 
ATOM   1831  C CB   . ALA A 1 269 ? 130.362 121.446 138.776 1.00 31.12  ?  269 ALA A CB   1 
ATOM   1832  H H    . ALA A 1 269 ? 132.352 120.459 139.768 1.00 31.12  ?  269 ALA A H    1 
ATOM   1833  H HA   . ALA A 1 269 ? 130.273 119.409 138.589 1.00 31.12  ?  269 ALA A HA   1 
ATOM   1834  H HB1  . ALA A 1 269 ? 129.594 121.614 138.208 1.00 31.12  ?  269 ALA A HB1  1 
ATOM   1835  H HB2  . ALA A 1 269 ? 131.036 122.128 138.631 1.00 31.12  ?  269 ALA A HB2  1 
ATOM   1836  H HB3  . ALA A 1 269 ? 130.091 121.441 139.707 1.00 31.12  ?  269 ALA A HB3  1 
ATOM   1837  N N    . LEU A 1 270 ? 132.483 120.568 136.583 1.00 31.13  ?  270 LEU A N    1 
ATOM   1838  C CA   . LEU A 1 270 ? 132.921 120.505 135.192 1.00 31.13  ?  270 LEU A CA   1 
ATOM   1839  C C    . LEU A 1 270 ? 133.120 119.062 134.742 1.00 31.13  ?  270 LEU A C    1 
ATOM   1840  O O    . LEU A 1 270 ? 132.694 118.682 133.644 1.00 31.13  ?  270 LEU A O    1 
ATOM   1841  C CB   . LEU A 1 270 ? 134.214 121.301 135.012 1.00 31.13  ?  270 LEU A CB   1 
ATOM   1842  C CG   . LEU A 1 270 ? 134.074 122.824 135.023 1.00 31.13  ?  270 LEU A CG   1 
ATOM   1843  C CD1  . LEU A 1 270 ? 135.429 123.482 135.231 1.00 31.13  ?  270 LEU A CD1  1 
ATOM   1844  C CD2  . LEU A 1 270 ? 133.432 123.315 133.736 1.00 31.13  ?  270 LEU A CD2  1 
ATOM   1845  H H    . LEU A 1 270 ? 133.027 120.971 137.113 1.00 31.13  ?  270 LEU A H    1 
ATOM   1846  H HA   . LEU A 1 270 ? 132.241 120.903 134.628 1.00 31.13  ?  270 LEU A HA   1 
ATOM   1847  H HB2  . LEU A 1 270 ? 134.821 121.061 135.729 1.00 31.13  ?  270 LEU A HB2  1 
ATOM   1848  H HB3  . LEU A 1 270 ? 134.608 121.054 134.161 1.00 31.13  ?  270 LEU A HB3  1 
ATOM   1849  H HG   . LEU A 1 270 ? 133.500 123.083 135.761 1.00 31.13  ?  270 LEU A HG   1 
ATOM   1850  H HD11 . LEU A 1 270 ? 135.791 123.197 136.085 1.00 31.13  ?  270 LEU A HD11 1 
ATOM   1851  H HD12 . LEU A 1 270 ? 135.316 124.445 135.225 1.00 31.13  ?  270 LEU A HD12 1 
ATOM   1852  H HD13 . LEU A 1 270 ? 136.024 123.213 134.514 1.00 31.13  ?  270 LEU A HD13 1 
ATOM   1853  H HD21 . LEU A 1 270 ? 132.532 122.959 133.675 1.00 31.13  ?  270 LEU A HD21 1 
ATOM   1854  H HD22 . LEU A 1 270 ? 133.404 124.285 133.748 1.00 31.13  ?  270 LEU A HD22 1 
ATOM   1855  H HD23 . LEU A 1 270 ? 133.961 123.010 132.983 1.00 31.13  ?  270 LEU A HD23 1 
ATOM   1856  N N    . LYS A 1 271 ? 133.764 118.244 135.578 1.00 31.85  ?  271 LYS A N    1 
ATOM   1857  C CA   . LYS A 1 271 ? 133.954 116.839 135.232 1.00 31.85  ?  271 LYS A CA   1 
ATOM   1858  C C    . LYS A 1 271 ? 132.622 116.109 135.108 1.00 31.85  ?  271 LYS A C    1 
ATOM   1859  O O    . LYS A 1 271 ? 132.441 115.304 134.187 1.00 31.85  ?  271 LYS A O    1 
ATOM   1860  C CB   . LYS A 1 271 ? 134.837 116.152 136.275 1.00 31.85  ?  271 LYS A CB   1 
ATOM   1861  C CG   . LYS A 1 271 ? 136.256 116.707 136.376 1.00 31.85  ?  271 LYS A CG   1 
ATOM   1862  C CD   . LYS A 1 271 ? 137.044 116.549 135.079 1.00 31.85  ?  271 LYS A CD   1 
ATOM   1863  C CE   . LYS A 1 271 ? 137.310 115.087 134.756 1.00 31.85  ?  271 LYS A CE   1 
ATOM   1864  N NZ   . LYS A 1 271 ? 138.200 114.929 133.573 1.00 31.85  1  271 LYS A NZ   1 
ATOM   1865  H H    . LYS A 1 271 ? 134.095 118.475 136.337 1.00 31.85  ?  271 LYS A H    1 
ATOM   1866  H HA   . LYS A 1 271 ? 134.397 116.783 134.372 1.00 31.85  ?  271 LYS A HA   1 
ATOM   1867  H HB2  . LYS A 1 271 ? 134.422 116.256 137.146 1.00 31.85  ?  271 LYS A HB2  1 
ATOM   1868  H HB3  . LYS A 1 271 ? 134.900 115.209 136.057 1.00 31.85  ?  271 LYS A HB3  1 
ATOM   1869  H HG2  . LYS A 1 271 ? 136.213 117.653 136.584 1.00 31.85  ?  271 LYS A HG2  1 
ATOM   1870  H HG3  . LYS A 1 271 ? 136.732 116.235 137.077 1.00 31.85  ?  271 LYS A HG3  1 
ATOM   1871  H HD2  . LYS A 1 271 ? 136.548 116.940 134.344 1.00 31.85  ?  271 LYS A HD2  1 
ATOM   1872  H HD3  . LYS A 1 271 ? 137.900 116.995 135.175 1.00 31.85  ?  271 LYS A HD3  1 
ATOM   1873  H HE2  . LYS A 1 271 ? 137.740 114.666 135.517 1.00 31.85  ?  271 LYS A HE2  1 
ATOM   1874  H HE3  . LYS A 1 271 ? 136.470 114.645 134.559 1.00 31.85  ?  271 LYS A HE3  1 
ATOM   1875  H HZ1  . LYS A 1 271 ? 138.343 114.066 133.413 1.00 31.85  ?  271 LYS A HZ1  1 
ATOM   1876  H HZ2  . LYS A 1 271 ? 137.822 115.297 132.856 1.00 31.85  ?  271 LYS A HZ2  1 
ATOM   1877  H HZ3  . LYS A 1 271 ? 138.981 115.328 133.725 1.00 31.85  ?  271 LYS A HZ3  1 
ATOM   1878  N N    . LEU A 1 272 ? 131.683 116.374 136.017 1.00 25.51  ?  272 LEU A N    1 
ATOM   1879  C CA   . LEU A 1 272 ? 130.371 115.743 135.929 1.00 25.51  ?  272 LEU A CA   1 
ATOM   1880  C C    . LEU A 1 272 ? 129.654 116.155 134.650 1.00 25.51  ?  272 LEU A C    1 
ATOM   1881  O O    . LEU A 1 272 ? 129.044 115.321 133.972 1.00 25.51  ?  272 LEU A O    1 
ATOM   1882  C CB   . LEU A 1 272 ? 129.535 116.105 137.158 1.00 25.51  ?  272 LEU A CB   1 
ATOM   1883  C CG   . LEU A 1 272 ? 128.130 115.500 137.230 1.00 25.51  ?  272 LEU A CG   1 
ATOM   1884  C CD1  . LEU A 1 272 ? 128.178 113.984 137.108 1.00 25.51  ?  272 LEU A CD1  1 
ATOM   1885  C CD2  . LEU A 1 272 ? 127.438 115.913 138.520 1.00 25.51  ?  272 LEU A CD2  1 
ATOM   1886  H H    . LEU A 1 272 ? 131.780 116.908 136.684 1.00 25.51  ?  272 LEU A H    1 
ATOM   1887  H HA   . LEU A 1 272 ? 130.486 114.780 135.913 1.00 25.51  ?  272 LEU A HA   1 
ATOM   1888  H HB2  . LEU A 1 272 ? 130.015 115.811 137.949 1.00 25.51  ?  272 LEU A HB2  1 
ATOM   1889  H HB3  . LEU A 1 272 ? 129.435 117.069 137.184 1.00 25.51  ?  272 LEU A HB3  1 
ATOM   1890  H HG   . LEU A 1 272 ? 127.604 115.840 136.490 1.00 25.51  ?  272 LEU A HG   1 
ATOM   1891  H HD11 . LEU A 1 272 ? 128.455 113.747 136.209 1.00 25.51  ?  272 LEU A HD11 1 
ATOM   1892  H HD12 . LEU A 1 272 ? 128.814 113.636 137.753 1.00 25.51  ?  272 LEU A HD12 1 
ATOM   1893  H HD13 . LEU A 1 272 ? 127.295 113.626 137.287 1.00 25.51  ?  272 LEU A HD13 1 
ATOM   1894  H HD21 . LEU A 1 272 ? 127.377 116.880 138.549 1.00 25.51  ?  272 LEU A HD21 1 
ATOM   1895  H HD22 . LEU A 1 272 ? 126.550 115.523 138.539 1.00 25.51  ?  272 LEU A HD22 1 
ATOM   1896  H HD23 . LEU A 1 272 ? 127.958 115.591 139.273 1.00 25.51  ?  272 LEU A HD23 1 
ATOM   1897  N N    . PHE A 1 273 ? 129.716 117.443 134.304 1.00 25.71  ?  273 PHE A N    1 
ATOM   1898  C CA   . PHE A 1 273 ? 129.086 117.909 133.074 1.00 25.71  ?  273 PHE A CA   1 
ATOM   1899  C C    . PHE A 1 273 ? 129.699 117.228 131.860 1.00 25.71  ?  273 PHE A C    1 
ATOM   1900  O O    . PHE A 1 273 ? 128.982 116.818 130.940 1.00 25.71  ?  273 PHE A O    1 
ATOM   1901  C CB   . PHE A 1 273 ? 129.220 119.428 132.963 1.00 25.71  ?  273 PHE A CB   1 
ATOM   1902  C CG   . PHE A 1 273 ? 128.585 120.007 131.730 1.00 25.71  ?  273 PHE A CG   1 
ATOM   1903  C CD1  . PHE A 1 273 ? 129.298 120.103 130.547 1.00 25.71  ?  273 PHE A CD1  1 
ATOM   1904  C CD2  . PHE A 1 273 ? 127.277 120.461 131.756 1.00 25.71  ?  273 PHE A CD2  1 
ATOM   1905  C CE1  . PHE A 1 273 ? 128.718 120.635 129.412 1.00 25.71  ?  273 PHE A CE1  1 
ATOM   1906  C CE2  . PHE A 1 273 ? 126.693 120.995 130.624 1.00 25.71  ?  273 PHE A CE2  1 
ATOM   1907  C CZ   . PHE A 1 273 ? 127.414 121.082 129.452 1.00 25.71  ?  273 PHE A CZ   1 
ATOM   1908  H H    . PHE A 1 273 ? 130.112 118.056 134.758 1.00 25.71  ?  273 PHE A H    1 
ATOM   1909  H HA   . PHE A 1 273 ? 128.141 117.690 133.098 1.00 25.71  ?  273 PHE A HA   1 
ATOM   1910  H HB2  . PHE A 1 273 ? 128.796 119.836 133.734 1.00 25.71  ?  273 PHE A HB2  1 
ATOM   1911  H HB3  . PHE A 1 273 ? 130.162 119.658 132.947 1.00 25.71  ?  273 PHE A HB3  1 
ATOM   1912  H HD1  . PHE A 1 273 ? 130.178 119.802 130.515 1.00 25.71  ?  273 PHE A HD1  1 
ATOM   1913  H HD2  . PHE A 1 273 ? 126.787 120.404 132.544 1.00 25.71  ?  273 PHE A HD2  1 
ATOM   1914  H HE1  . PHE A 1 273 ? 129.206 120.693 128.623 1.00 25.71  ?  273 PHE A HE1  1 
ATOM   1915  H HE2  . PHE A 1 273 ? 125.813 121.296 130.653 1.00 25.71  ?  273 PHE A HE2  1 
ATOM   1916  H HZ   . PHE A 1 273 ? 127.022 121.442 128.689 1.00 25.71  ?  273 PHE A HZ   1 
ATOM   1917  N N    . ASP A 1 274 ? 131.027 117.099 131.842 1.00 26.00  ?  274 ASP A N    1 
ATOM   1918  C CA   . ASP A 1 274 ? 131.684 116.391 130.749 1.00 26.00  ?  274 ASP A CA   1 
ATOM   1919  C C    . ASP A 1 274 ? 131.197 114.950 130.675 1.00 26.00  ?  274 ASP A C    1 
ATOM   1920  O O    . ASP A 1 274 ? 130.938 114.422 129.588 1.00 26.00  ?  274 ASP A O    1 
ATOM   1921  C CB   . ASP A 1 274 ? 133.202 116.440 130.936 1.00 26.00  ?  274 ASP A CB   1 
ATOM   1922  C CG   . ASP A 1 274 ? 133.956 115.751 129.812 1.00 26.00  ?  274 ASP A CG   1 
ATOM   1923  O OD1  . ASP A 1 274 ? 133.309 115.251 128.868 1.00 26.00  ?  274 ASP A OD1  1 
ATOM   1924  O OD2  . ASP A 1 274 ? 135.203 115.710 129.873 1.00 26.00  -1 274 ASP A OD2  1 
ATOM   1925  H H    . ASP A 1 274 ? 131.560 117.408 132.441 1.00 26.00  ?  274 ASP A H    1 
ATOM   1926  H HA   . ASP A 1 274 ? 131.465 116.825 129.910 1.00 26.00  ?  274 ASP A HA   1 
ATOM   1927  H HB2  . ASP A 1 274 ? 133.489 117.366 130.969 1.00 26.00  ?  274 ASP A HB2  1 
ATOM   1928  H HB3  . ASP A 1 274 ? 133.431 115.994 131.766 1.00 26.00  ?  274 ASP A HB3  1 
ATOM   1929  N N    . SER A 1 275 ? 131.066 114.298 131.831 1.00 25.72  ?  275 SER A N    1 
ATOM   1930  C CA   . SER A 1 275 ? 130.626 112.908 131.849 1.00 25.72  ?  275 SER A CA   1 
ATOM   1931  C C    . SER A 1 275 ? 129.215 112.764 131.288 1.00 25.72  ?  275 SER A C    1 
ATOM   1932  O O    . SER A 1 275 ? 128.953 111.871 130.474 1.00 25.72  ?  275 SER A O    1 
ATOM   1933  C CB   . SER A 1 275 ? 130.697 112.359 133.272 1.00 25.72  ?  275 SER A CB   1 
ATOM   1934  O OG   . SER A 1 275 ? 132.032 112.352 133.748 1.00 25.72  ?  275 SER A OG   1 
ATOM   1935  H H    . SER A 1 275 ? 131.224 114.634 132.607 1.00 25.72  ?  275 SER A H    1 
ATOM   1936  H HA   . SER A 1 275 ? 131.224 112.383 131.295 1.00 25.72  ?  275 SER A HA   1 
ATOM   1937  H HB2  . SER A 1 275 ? 130.156 112.915 133.854 1.00 25.72  ?  275 SER A HB2  1 
ATOM   1938  H HB3  . SER A 1 275 ? 130.361 111.452 133.271 1.00 25.72  ?  275 SER A HB3  1 
ATOM   1939  H HG   . SER A 1 275 ? 132.053 112.071 134.540 1.00 25.72  ?  275 SER A HG   1 
ATOM   1940  N N    . ILE A 1 276 ? 128.291 113.633 131.704 1.00 23.01  ?  276 ILE A N    1 
ATOM   1941  C CA   . ILE A 1 276 ? 126.927 113.552 131.179 1.00 23.01  ?  276 ILE A CA   1 
ATOM   1942  C C    . ILE A 1 276 ? 126.916 113.838 129.682 1.00 23.01  ?  276 ILE A C    1 
ATOM   1943  O O    . ILE A 1 276 ? 126.246 113.145 128.907 1.00 23.01  ?  276 ILE A O    1 
ATOM   1944  C CB   . ILE A 1 276 ? 125.978 114.499 131.941 1.00 23.01  ?  276 ILE A CB   1 
ATOM   1945  C CG1  . ILE A 1 276 ? 126.174 114.384 133.452 1.00 23.01  ?  276 ILE A CG1  1 
ATOM   1946  C CG2  . ILE A 1 276 ? 124.527 114.197 131.594 1.00 23.01  ?  276 ILE A CG2  1 
ATOM   1947  C CD1  . ILE A 1 276 ? 125.198 115.207 134.257 1.00 23.01  ?  276 ILE A CD1  1 
ATOM   1948  H H    . ILE A 1 276 ? 128.429 114.266 132.268 1.00 23.01  ?  276 ILE A H    1 
ATOM   1949  H HA   . ILE A 1 276 ? 126.601 112.648 131.307 1.00 23.01  ?  276 ILE A HA   1 
ATOM   1950  H HB   . ILE A 1 276 ? 126.175 115.410 131.674 1.00 23.01  ?  276 ILE A HB   1 
ATOM   1951  H HG12 . ILE A 1 276 ? 126.065 113.456 133.713 1.00 23.01  ?  276 ILE A HG12 1 
ATOM   1952  H HG13 . ILE A 1 276 ? 127.055 114.685 133.683 1.00 23.01  ?  276 ILE A HG13 1 
ATOM   1953  H HG21 . ILE A 1 276 ? 123.988 114.981 131.781 1.00 23.01  ?  276 ILE A HG21 1 
ATOM   1954  H HG22 . ILE A 1 276 ? 124.460 113.968 130.654 1.00 23.01  ?  276 ILE A HG22 1 
ATOM   1955  H HG23 . ILE A 1 276 ? 124.227 113.452 132.137 1.00 23.01  ?  276 ILE A HG23 1 
ATOM   1956  H HD11 . ILE A 1 276 ? 125.522 115.275 135.169 1.00 23.01  ?  276 ILE A HD11 1 
ATOM   1957  H HD12 . ILE A 1 276 ? 125.132 116.091 133.863 1.00 23.01  ?  276 ILE A HD12 1 
ATOM   1958  H HD13 . ILE A 1 276 ? 124.330 114.774 134.244 1.00 23.01  ?  276 ILE A HD13 1 
ATOM   1959  N N    . TRP A 1 277 ? 127.655 114.862 129.251 1.00 22.76  ?  277 TRP A N    1 
ATOM   1960  C CA   . TRP A 1 277 ? 127.621 115.244 127.843 1.00 22.76  ?  277 TRP A CA   1 
ATOM   1961  C C    . TRP A 1 277 ? 128.201 114.150 126.954 1.00 22.76  ?  277 TRP A C    1 
ATOM   1962  O O    . TRP A 1 277 ? 127.675 113.886 125.866 1.00 22.76  ?  277 TRP A O    1 
ATOM   1963  C CB   . TRP A 1 277 ? 128.375 116.557 127.639 1.00 22.76  ?  277 TRP A CB   1 
ATOM   1964  C CG   . TRP A 1 277 ? 128.271 117.084 126.243 1.00 22.76  ?  277 TRP A CG   1 
ATOM   1965  C CD1  . TRP A 1 277 ? 129.108 116.817 125.201 1.00 22.76  ?  277 TRP A CD1  1 
ATOM   1966  C CD2  . TRP A 1 277 ? 127.259 117.958 125.732 1.00 22.76  ?  277 TRP A CD2  1 
ATOM   1967  N NE1  . TRP A 1 277 ? 128.685 117.478 124.073 1.00 22.76  ?  277 TRP A NE1  1 
ATOM   1968  C CE2  . TRP A 1 277 ? 127.550 118.185 124.373 1.00 22.76  ?  277 TRP A CE2  1 
ATOM   1969  C CE3  . TRP A 1 277 ? 126.135 118.574 126.293 1.00 22.76  ?  277 TRP A CE3  1 
ATOM   1970  C CZ2  . TRP A 1 277 ? 126.760 119.001 123.566 1.00 22.76  ?  277 TRP A CZ2  1 
ATOM   1971  C CZ3  . TRP A 1 277 ? 125.353 119.384 125.491 1.00 22.76  ?  277 TRP A CZ3  1 
ATOM   1972  C CH2  . TRP A 1 277 ? 125.669 119.590 124.143 1.00 22.76  ?  277 TRP A CH2  1 
ATOM   1973  H H    . TRP A 1 277 ? 128.173 115.341 129.743 1.00 22.76  ?  277 TRP A H    1 
ATOM   1974  H HA   . TRP A 1 277 ? 126.699 115.385 127.579 1.00 22.76  ?  277 TRP A HA   1 
ATOM   1975  H HB2  . TRP A 1 277 ? 128.011 117.226 128.239 1.00 22.76  ?  277 TRP A HB2  1 
ATOM   1976  H HB3  . TRP A 1 277 ? 129.314 116.414 127.834 1.00 22.76  ?  277 TRP A HB3  1 
ATOM   1977  H HD1  . TRP A 1 277 ? 129.859 116.271 125.247 1.00 22.76  ?  277 TRP A HD1  1 
ATOM   1978  H HE1  . TRP A 1 277 ? 129.068 117.451 123.304 1.00 22.76  ?  277 TRP A HE1  1 
ATOM   1979  H HE3  . TRP A 1 277 ? 125.919 118.442 127.188 1.00 22.76  ?  277 TRP A HE3  1 
ATOM   1980  H HZ2  . TRP A 1 277 ? 126.968 119.140 122.671 1.00 22.76  ?  277 TRP A HZ2  1 
ATOM   1981  H HZ3  . TRP A 1 277 ? 124.604 119.799 125.853 1.00 22.76  ?  277 TRP A HZ3  1 
ATOM   1982  H HH2  . TRP A 1 277 ? 125.125 120.140 123.628 1.00 22.76  ?  277 TRP A HH2  1 
ATOM   1983  N N    . ASN A 1 278 ? 129.277 113.503 127.394 1.00 24.10  ?  278 ASN A N    1 
ATOM   1984  C CA   . ASN A 1 278 ? 129.968 112.507 126.586 1.00 24.10  ?  278 ASN A CA   1 
ATOM   1985  C C    . ASN A 1 278 ? 129.474 111.086 126.830 1.00 24.10  ?  278 ASN A C    1 
ATOM   1986  O O    . ASN A 1 278 ? 130.040 110.147 126.262 1.00 24.10  ?  278 ASN A O    1 
ATOM   1987  C CB   . ASN A 1 278 ? 131.475 112.573 126.850 1.00 24.10  ?  278 ASN A CB   1 
ATOM   1988  C CG   . ASN A 1 278 ? 132.074 113.914 126.478 1.00 24.10  ?  278 ASN A CG   1 
ATOM   1989  O OD1  . ASN A 1 278 ? 131.378 114.929 126.442 1.00 24.10  ?  278 ASN A OD1  1 
ATOM   1990  N ND2  . ASN A 1 278 ? 133.372 113.926 126.198 1.00 24.10  ?  278 ASN A ND2  1 
ATOM   1991  H H    . ASN A 1 278 ? 129.630 113.626 128.168 1.00 24.10  ?  278 ASN A H    1 
ATOM   1992  H HA   . ASN A 1 278 ? 129.824 112.711 125.649 1.00 24.10  ?  278 ASN A HA   1 
ATOM   1993  H HB2  . ASN A 1 278 ? 131.638 112.423 127.795 1.00 24.10  ?  278 ASN A HB2  1 
ATOM   1994  H HB3  . ASN A 1 278 ? 131.919 111.890 126.324 1.00 24.10  ?  278 ASN A HB3  1 
ATOM   1995  H HD21 . ASN A 1 278 ? 133.826 113.197 126.234 1.00 24.10  ?  278 ASN A HD21 1 
ATOM   1996  H HD22 . ASN A 1 278 ? 133.758 114.664 125.981 1.00 24.10  ?  278 ASN A HD22 1 
ATOM   1997  N N    . ASN A 1 279 ? 128.446 110.901 127.653 1.00 24.14  ?  279 ASN A N    1 
ATOM   1998  C CA   . ASN A 1 279 ? 127.941 109.561 127.918 1.00 24.14  ?  279 ASN A CA   1 
ATOM   1999  C C    . ASN A 1 279 ? 127.330 108.967 126.654 1.00 24.14  ?  279 ASN A C    1 
ATOM   2000  O O    . ASN A 1 279 ? 126.743 109.677 125.833 1.00 24.14  ?  279 ASN A O    1 
ATOM   2001  C CB   . ASN A 1 279 ? 126.907 109.593 129.041 1.00 24.14  ?  279 ASN A CB   1 
ATOM   2002  C CG   . ASN A 1 279 ? 126.281 108.235 129.294 1.00 24.14  ?  279 ASN A CG   1 
ATOM   2003  O OD1  . ASN A 1 279 ? 125.192 107.939 128.804 1.00 24.14  ?  279 ASN A OD1  1 
ATOM   2004  N ND2  . ASN A 1 279 ? 126.971 107.401 130.063 1.00 24.14  ?  279 ASN A ND2  1 
ATOM   2005  H H    . ASN A 1 279 ? 128.026 111.528 128.065 1.00 24.14  ?  279 ASN A H    1 
ATOM   2006  H HA   . ASN A 1 279 ? 128.676 108.992 128.195 1.00 24.14  ?  279 ASN A HA   1 
ATOM   2007  H HB2  . ASN A 1 279 ? 127.338 109.882 129.860 1.00 24.14  ?  279 ASN A HB2  1 
ATOM   2008  H HB3  . ASN A 1 279 ? 126.200 110.210 128.802 1.00 24.14  ?  279 ASN A HB3  1 
ATOM   2009  H HD21 . ASN A 1 279 ? 127.730 107.643 130.388 1.00 24.14  ?  279 ASN A HD21 1 
ATOM   2010  H HD22 . ASN A 1 279 ? 126.659 106.618 130.237 1.00 24.14  ?  279 ASN A HD22 1 
ATOM   2011  N N    . LYS A 1 280 ? 127.473 107.648 126.504 1.00 23.76  ?  280 LYS A N    1 
ATOM   2012  C CA   . LYS A 1 280 ? 127.020 106.986 125.285 1.00 23.76  ?  280 LYS A CA   1 
ATOM   2013  C C    . LYS A 1 280 ? 125.512 107.116 125.102 1.00 23.76  ?  280 LYS A C    1 
ATOM   2014  O O    . LYS A 1 280 ? 125.035 107.386 123.993 1.00 23.76  ?  280 LYS A O    1 
ATOM   2015  C CB   . LYS A 1 280 ? 127.428 105.512 125.316 1.00 23.76  ?  280 LYS A CB   1 
ATOM   2016  C CG   . LYS A 1 280 ? 127.002 104.716 124.090 1.00 23.76  ?  280 LYS A CG   1 
ATOM   2017  C CD   . LYS A 1 280 ? 127.413 103.255 124.200 1.00 23.76  ?  280 LYS A CD   1 
ATOM   2018  C CE   . LYS A 1 280 ? 128.922 103.086 124.115 1.00 23.76  ?  280 LYS A CE   1 
ATOM   2019  N NZ   . LYS A 1 280 ? 129.318 101.654 124.019 1.00 23.76  1  280 LYS A NZ   1 
ATOM   2020  H H    . LYS A 1 280 ? 127.825 107.123 127.086 1.00 23.76  ?  280 LYS A H    1 
ATOM   2021  H HA   . LYS A 1 280 ? 127.451 107.400 124.522 1.00 23.76  ?  280 LYS A HA   1 
ATOM   2022  H HB2  . LYS A 1 280 ? 128.394 105.462 125.381 1.00 23.76  ?  280 LYS A HB2  1 
ATOM   2023  H HB3  . LYS A 1 280 ? 127.025 105.094 126.093 1.00 23.76  ?  280 LYS A HB3  1 
ATOM   2024  H HG2  . LYS A 1 280 ? 126.037 104.748 124.002 1.00 23.76  ?  280 LYS A HG2  1 
ATOM   2025  H HG3  . LYS A 1 280 ? 127.424 105.092 123.302 1.00 23.76  ?  280 LYS A HG3  1 
ATOM   2026  H HD2  . LYS A 1 280 ? 127.117 102.903 125.054 1.00 23.76  ?  280 LYS A HD2  1 
ATOM   2027  H HD3  . LYS A 1 280 ? 127.011 102.754 123.474 1.00 23.76  ?  280 LYS A HD3  1 
ATOM   2028  H HE2  . LYS A 1 280 ? 129.250 103.544 123.325 1.00 23.76  ?  280 LYS A HE2  1 
ATOM   2029  H HE3  . LYS A 1 280 ? 129.331 103.458 124.912 1.00 23.76  ?  280 LYS A HE3  1 
ATOM   2030  H HZ1  . LYS A 1 280 ? 130.204 101.586 123.974 1.00 23.76  ?  280 LYS A HZ1  1 
ATOM   2031  H HZ2  . LYS A 1 280 ? 128.963 101.289 123.289 1.00 23.76  ?  280 LYS A HZ2  1 
ATOM   2032  H HZ3  . LYS A 1 280 ? 129.030 101.210 124.734 1.00 23.76  ?  280 LYS A HZ3  1 
ATOM   2033  N N    . TRP A 1 281 ? 124.745 106.927 126.175 1.00 20.00  ?  281 TRP A N    1 
ATOM   2034  C CA   . TRP A 1 281 ? 123.291 106.915 126.074 1.00 20.00  ?  281 TRP A CA   1 
ATOM   2035  C C    . TRP A 1 281 ? 122.667 108.295 126.231 1.00 20.00  ?  281 TRP A C    1 
ATOM   2036  O O    . TRP A 1 281 ? 121.511 108.488 125.839 1.00 20.00  ?  281 TRP A O    1 
ATOM   2037  C CB   . TRP A 1 281 ? 122.702 105.970 127.126 1.00 20.00  ?  281 TRP A CB   1 
ATOM   2038  C CG   . TRP A 1 281 ? 123.302 104.599 127.090 1.00 20.00  ?  281 TRP A CG   1 
ATOM   2039  C CD1  . TRP A 1 281 ? 124.107 104.031 128.033 1.00 20.00  ?  281 TRP A CD1  1 
ATOM   2040  C CD2  . TRP A 1 281 ? 123.147 103.623 126.054 1.00 20.00  ?  281 TRP A CD2  1 
ATOM   2041  N NE1  . TRP A 1 281 ? 124.461 102.760 127.649 1.00 20.00  ?  281 TRP A NE1  1 
ATOM   2042  C CE2  . TRP A 1 281 ? 123.885 102.486 126.437 1.00 20.00  ?  281 TRP A CE2  1 
ATOM   2043  C CE3  . TRP A 1 281 ? 122.454 103.600 124.839 1.00 20.00  ?  281 TRP A CE3  1 
ATOM   2044  C CZ2  . TRP A 1 281 ? 123.950 101.339 125.649 1.00 20.00  ?  281 TRP A CZ2  1 
ATOM   2045  C CZ3  . TRP A 1 281 ? 122.521 102.460 124.059 1.00 20.00  ?  281 TRP A CZ3  1 
ATOM   2046  C CH2  . TRP A 1 281 ? 123.263 101.346 124.467 1.00 20.00  ?  281 TRP A CH2  1 
ATOM   2047  H H    . TRP A 1 281 ? 125.045 106.803 126.972 1.00 20.00  ?  281 TRP A H    1 
ATOM   2048  H HA   . TRP A 1 281 ? 123.041 106.576 125.201 1.00 20.00  ?  281 TRP A HA   1 
ATOM   2049  H HB2  . TRP A 1 281 ? 122.861 106.343 128.007 1.00 20.00  ?  281 TRP A HB2  1 
ATOM   2050  H HB3  . TRP A 1 281 ? 121.748 105.883 126.971 1.00 20.00  ?  281 TRP A HB3  1 
ATOM   2051  H HD1  . TRP A 1 281 ? 124.376 104.443 128.822 1.00 20.00  ?  281 TRP A HD1  1 
ATOM   2052  H HE1  . TRP A 1 281 ? 124.964 102.224 128.096 1.00 20.00  ?  281 TRP A HE1  1 
ATOM   2053  H HE3  . TRP A 1 281 ? 121.959 104.337 124.561 1.00 20.00  ?  281 TRP A HE3  1 
ATOM   2054  H HZ2  . TRP A 1 281 ? 124.442 100.597 125.917 1.00 20.00  ?  281 TRP A HZ2  1 
ATOM   2055  H HZ3  . TRP A 1 281 ? 122.064 102.434 123.249 1.00 20.00  ?  281 TRP A HZ3  1 
ATOM   2056  H HH2  . TRP A 1 281 ? 123.289 100.593 123.922 1.00 20.00  ?  281 TRP A HH2  1 
ATOM   2057  N N    . LEU A 1 282 ? 123.399 109.258 126.789 1.00 21.38  ?  282 LEU A N    1 
ATOM   2058  C CA   . LEU A 1 282 ? 122.869 110.600 126.989 1.00 21.38  ?  282 LEU A CA   1 
ATOM   2059  C C    . LEU A 1 282 ? 123.208 111.550 125.848 1.00 21.38  ?  282 LEU A C    1 
ATOM   2060  O O    . LEU A 1 282 ? 122.897 112.742 125.946 1.00 21.38  ?  282 LEU A O    1 
ATOM   2061  C CB   . LEU A 1 282 ? 123.390 111.176 128.309 1.00 21.38  ?  282 LEU A CB   1 
ATOM   2062  C CG   . LEU A 1 282 ? 123.071 110.349 129.557 1.00 21.38  ?  282 LEU A CG   1 
ATOM   2063  C CD1  . LEU A 1 282 ? 123.747 110.943 130.780 1.00 21.38  ?  282 LEU A CD1  1 
ATOM   2064  C CD2  . LEU A 1 282 ? 121.568 110.252 129.772 1.00 21.38  ?  282 LEU A CD2  1 
ATOM   2065  H H    . LEU A 1 282 ? 124.208 109.156 127.061 1.00 21.38  ?  282 LEU A H    1 
ATOM   2066  H HA   . LEU A 1 282 ? 121.902 110.550 127.051 1.00 21.38  ?  282 LEU A HA   1 
ATOM   2067  H HB2  . LEU A 1 282 ? 124.354 111.258 128.249 1.00 21.38  ?  282 LEU A HB2  1 
ATOM   2068  H HB3  . LEU A 1 282 ? 122.999 112.054 128.435 1.00 21.38  ?  282 LEU A HB3  1 
ATOM   2069  H HG   . LEU A 1 282 ? 123.412 109.450 129.435 1.00 21.38  ?  282 LEU A HG   1 
ATOM   2070  H HD11 . LEU A 1 282 ? 124.686 111.087 130.584 1.00 21.38  ?  282 LEU A HD11 1 
ATOM   2071  H HD12 . LEU A 1 282 ? 123.653 110.326 131.523 1.00 21.38  ?  282 LEU A HD12 1 
ATOM   2072  H HD13 . LEU A 1 282 ? 123.319 111.786 130.993 1.00 21.38  ?  282 LEU A HD13 1 
ATOM   2073  H HD21 . LEU A 1 282 ? 121.179 109.727 129.055 1.00 21.38  ?  282 LEU A HD21 1 
ATOM   2074  H HD22 . LEU A 1 282 ? 121.400 109.822 130.625 1.00 21.38  ?  282 LEU A HD22 1 
ATOM   2075  H HD23 . LEU A 1 282 ? 121.191 111.145 129.772 1.00 21.38  ?  282 LEU A HD23 1 
ATOM   2076  N N    . ARG A 1 283 ? 123.832 111.060 124.775 1.00 25.00  ?  283 ARG A N    1 
ATOM   2077  C CA   . ARG A 1 283 ? 124.184 111.916 123.649 1.00 25.00  ?  283 ARG A CA   1 
ATOM   2078  C C    . ARG A 1 283 ? 122.965 112.476 122.928 1.00 25.00  ?  283 ARG A C    1 
ATOM   2079  O O    . ARG A 1 283 ? 123.110 113.436 122.163 1.00 25.00  ?  283 ARG A O    1 
ATOM   2080  C CB   . ARG A 1 283 ? 125.056 111.141 122.659 1.00 25.00  ?  283 ARG A CB   1 
ATOM   2081  C CG   . ARG A 1 283 ? 124.361 109.947 122.021 1.00 25.00  ?  283 ARG A CG   1 
ATOM   2082  C CD   . ARG A 1 283 ? 125.261 109.194 121.043 1.00 25.00  ?  283 ARG A CD   1 
ATOM   2083  N NE   . ARG A 1 283 ? 126.458 108.639 121.674 1.00 25.00  ?  283 ARG A NE   1 
ATOM   2084  C CZ   . ARG A 1 283 ? 127.604 109.295 121.841 1.00 25.00  ?  283 ARG A CZ   1 
ATOM   2085  N NH1  . ARG A 1 283 ? 128.628 108.693 122.430 1.00 25.00  1  283 ARG A NH1  1 
ATOM   2086  N NH2  . ARG A 1 283 ? 127.738 110.545 121.415 1.00 25.00  ?  283 ARG A NH2  1 
ATOM   2087  H H    . ARG A 1 283 ? 124.061 110.237 124.677 1.00 25.00  ?  283 ARG A H    1 
ATOM   2088  H HA   . ARG A 1 283 ? 124.704 112.666 123.979 1.00 25.00  ?  283 ARG A HA   1 
ATOM   2089  H HB2  . ARG A 1 283 ? 125.331 111.740 121.948 1.00 25.00  ?  283 ARG A HB2  1 
ATOM   2090  H HB3  . ARG A 1 283 ? 125.835 110.812 123.133 1.00 25.00  ?  283 ARG A HB3  1 
ATOM   2091  H HG2  . ARG A 1 283 ? 124.090 109.328 122.717 1.00 25.00  ?  283 ARG A HG2  1 
ATOM   2092  H HG3  . ARG A 1 283 ? 123.583 110.255 121.531 1.00 25.00  ?  283 ARG A HG3  1 
ATOM   2093  H HD2  . ARG A 1 283 ? 124.759 108.456 120.664 1.00 25.00  ?  283 ARG A HD2  1 
ATOM   2094  H HD3  . ARG A 1 283 ? 125.539 109.798 120.337 1.00 25.00  ?  283 ARG A HD3  1 
ATOM   2095  H HE   . ARG A 1 283 ? 126.415 107.832 121.968 1.00 25.00  ?  283 ARG A HE   1 
ATOM   2096  H HH11 . ARG A 1 283 ? 128.549 107.882 122.707 1.00 25.00  ?  283 ARG A HH11 1 
ATOM   2097  H HH12 . ARG A 1 283 ? 129.371 109.113 122.536 1.00 25.00  ?  283 ARG A HH12 1 
ATOM   2098  H HH21 . ARG A 1 283 ? 127.082 110.946 121.032 1.00 25.00  ?  283 ARG A HH21 1 
ATOM   2099  H HH22 . ARG A 1 283 ? 128.484 110.957 121.527 1.00 25.00  ?  283 ARG A HH22 1 
ATOM   2100  N N    . ASP A 1 284 ? 121.781 111.908 123.147 1.00 23.43  ?  284 ASP A N    1 
ATOM   2101  C CA   . ASP A 1 284 ? 120.557 112.375 122.513 1.00 23.43  ?  284 ASP A CA   1 
ATOM   2102  C C    . ASP A 1 284 ? 119.800 113.391 123.358 1.00 23.43  ?  284 ASP A C    1 
ATOM   2103  O O    . ASP A 1 284 ? 118.722 113.832 122.951 1.00 23.43  ?  284 ASP A O    1 
ATOM   2104  C CB   . ASP A 1 284 ? 119.638 111.186 122.207 1.00 23.43  ?  284 ASP A CB   1 
ATOM   2105  C CG   . ASP A 1 284 ? 120.207 110.266 121.146 1.00 23.43  ?  284 ASP A CG   1 
ATOM   2106  O OD1  . ASP A 1 284 ? 120.963 110.750 120.280 1.00 23.43  ?  284 ASP A OD1  1 
ATOM   2107  O OD2  . ASP A 1 284 ? 119.897 109.056 121.180 1.00 23.43  -1 284 ASP A OD2  1 
ATOM   2108  H H    . ASP A 1 284 ? 121.661 111.237 123.670 1.00 23.43  ?  284 ASP A H    1 
ATOM   2109  H HA   . ASP A 1 284 ? 120.782 112.801 121.671 1.00 23.43  ?  284 ASP A HA   1 
ATOM   2110  H HB2  . ASP A 1 284 ? 119.511 110.669 123.017 1.00 23.43  ?  284 ASP A HB2  1 
ATOM   2111  H HB3  . ASP A 1 284 ? 118.785 111.520 121.889 1.00 23.43  ?  284 ASP A HB3  1 
ATOM   2112  N N    . THR A 1 285 ? 120.333 113.771 124.516 1.00 21.98  ?  285 THR A N    1 
ATOM   2113  C CA   . THR A 1 285 ? 119.650 114.654 125.453 1.00 21.98  ?  285 THR A CA   1 
ATOM   2114  C C    . THR A 1 285 ? 120.399 115.978 125.537 1.00 21.98  ?  285 THR A C    1 
ATOM   2115  O O    . THR A 1 285 ? 121.620 115.994 125.723 1.00 21.98  ?  285 THR A O    1 
ATOM   2116  C CB   . THR A 1 285 ? 119.555 114.011 126.837 1.00 21.98  ?  285 THR A CB   1 
ATOM   2117  O OG1  . THR A 1 285 ? 119.088 112.661 126.710 1.00 21.98  ?  285 THR A OG1  1 
ATOM   2118  C CG2  . THR A 1 285 ? 118.602 114.794 127.728 1.00 21.98  ?  285 THR A CG2  1 
ATOM   2119  H H    . THR A 1 285 ? 121.111 113.524 124.788 1.00 21.98  ?  285 THR A H    1 
ATOM   2120  H HA   . THR A 1 285 ? 118.751 114.832 125.137 1.00 21.98  ?  285 THR A HA   1 
ATOM   2121  H HB   . THR A 1 285 ? 120.431 114.010 127.253 1.00 21.98  ?  285 THR A HB   1 
ATOM   2122  H HG1  . THR A 1 285 ? 118.328 112.652 126.353 1.00 21.98  ?  285 THR A HG1  1 
ATOM   2123  H HG21 . THR A 1 285 ? 118.524 114.357 128.590 1.00 21.98  ?  285 THR A HG21 1 
ATOM   2124  H HG22 . THR A 1 285 ? 118.936 115.694 127.862 1.00 21.98  ?  285 THR A HG22 1 
ATOM   2125  H HG23 . THR A 1 285 ? 117.725 114.840 127.317 1.00 21.98  ?  285 THR A HG23 1 
ATOM   2126  N N    . SER A 1 286 ? 119.666 117.079 125.400 1.00 22.34  ?  286 SER A N    1 
ATOM   2127  C CA   . SER A 1 286 ? 120.240 118.401 125.593 1.00 22.34  ?  286 SER A CA   1 
ATOM   2128  C C    . SER A 1 286 ? 120.320 118.724 127.080 1.00 22.34  ?  286 SER A C    1 
ATOM   2129  O O    . SER A 1 286 ? 119.535 118.221 127.890 1.00 22.34  ?  286 SER A O    1 
ATOM   2130  C CB   . SER A 1 286 ? 119.407 119.460 124.872 1.00 22.34  ?  286 SER A CB   1 
ATOM   2131  O OG   . SER A 1 286 ? 119.595 119.388 123.469 1.00 22.34  ?  286 SER A OG   1 
ATOM   2132  H H    . SER A 1 286 ? 118.831 117.085 125.195 1.00 22.34  ?  286 SER A H    1 
ATOM   2133  H HA   . SER A 1 286 ? 121.138 118.418 125.228 1.00 22.34  ?  286 SER A HA   1 
ATOM   2134  H HB2  . SER A 1 286 ? 118.469 119.314 125.071 1.00 22.34  ?  286 SER A HB2  1 
ATOM   2135  H HB3  . SER A 1 286 ? 119.678 120.339 125.181 1.00 22.34  ?  286 SER A HB3  1 
ATOM   2136  H HG   . SER A 1 286 ? 119.364 118.631 123.187 1.00 22.34  ?  286 SER A HG   1 
ATOM   2137  N N    . VAL A 1 287 ? 121.281 119.572 127.436 1.00 22.13  ?  287 VAL A N    1 
ATOM   2138  C CA   . VAL A 1 287 ? 121.547 119.928 128.826 1.00 22.13  ?  287 VAL A CA   1 
ATOM   2139  C C    . VAL A 1 287 ? 121.302 121.421 128.986 1.00 22.13  ?  287 VAL A C    1 
ATOM   2140  O O    . VAL A 1 287 ? 121.858 122.234 128.238 1.00 22.13  ?  287 VAL A O    1 
ATOM   2141  C CB   . VAL A 1 287 ? 122.979 119.556 129.246 1.00 22.13  ?  287 VAL A CB   1 
ATOM   2142  C CG1  . VAL A 1 287 ? 123.189 119.820 130.737 1.00 22.13  ?  287 VAL A CG1  1 
ATOM   2143  C CG2  . VAL A 1 287 ? 123.289 118.096 128.911 1.00 22.13  ?  287 VAL A CG2  1 
ATOM   2144  H H    . VAL A 1 287 ? 121.803 119.963 126.877 1.00 22.13  ?  287 VAL A H    1 
ATOM   2145  H HA   . VAL A 1 287 ? 120.930 119.455 129.405 1.00 22.13  ?  287 VAL A HA   1 
ATOM   2146  H HB   . VAL A 1 287 ? 123.604 120.113 128.755 1.00 22.13  ?  287 VAL A HB   1 
ATOM   2147  H HG11 . VAL A 1 287 ? 122.728 120.632 130.994 1.00 22.13  ?  287 VAL A HG11 1 
ATOM   2148  H HG12 . VAL A 1 287 ? 122.840 119.071 131.245 1.00 22.13  ?  287 VAL A HG12 1 
ATOM   2149  H HG13 . VAL A 1 287 ? 124.139 119.919 130.905 1.00 22.13  ?  287 VAL A HG13 1 
ATOM   2150  H HG21 . VAL A 1 287 ? 122.799 117.826 128.120 1.00 22.13  ?  287 VAL A HG21 1 
ATOM   2151  H HG22 . VAL A 1 287 ? 124.241 118.012 128.749 1.00 22.13  ?  287 VAL A HG22 1 
ATOM   2152  H HG23 . VAL A 1 287 ? 123.036 117.538 129.663 1.00 22.13  ?  287 VAL A HG23 1 
ATOM   2153  N N    . ILE A 1 288 ? 120.471 121.778 129.960 1.00 24.22  ?  288 ILE A N    1 
ATOM   2154  C CA   . ILE A 1 288 ? 120.243 123.171 130.325 1.00 24.22  ?  288 ILE A CA   1 
ATOM   2155  C C    . ILE A 1 288 ? 121.155 123.481 131.507 1.00 24.22  ?  288 ILE A C    1 
ATOM   2156  O O    . ILE A 1 288 ? 120.948 122.975 132.613 1.00 24.22  ?  288 ILE A O    1 
ATOM   2157  C CB   . ILE A 1 288 ? 118.771 123.431 130.668 1.00 24.22  ?  288 ILE A CB   1 
ATOM   2158  C CG1  . ILE A 1 288 ? 117.897 123.246 129.425 1.00 24.22  ?  288 ILE A CG1  1 
ATOM   2159  C CG2  . ILE A 1 288 ? 118.599 124.832 131.239 1.00 24.22  ?  288 ILE A CG2  1 
ATOM   2160  C CD1  . ILE A 1 288 ? 116.413 123.169 129.722 1.00 24.22  ?  288 ILE A CD1  1 
ATOM   2161  H H    . ILE A 1 288 ? 120.018 121.220 130.433 1.00 24.22  ?  288 ILE A H    1 
ATOM   2162  H HA   . ILE A 1 288 ? 120.491 123.747 129.586 1.00 24.22  ?  288 ILE A HA   1 
ATOM   2163  H HB   . ILE A 1 288 ? 118.493 122.788 131.340 1.00 24.22  ?  288 ILE A HB   1 
ATOM   2164  H HG12 . ILE A 1 288 ? 118.041 123.997 128.828 1.00 24.22  ?  288 ILE A HG12 1 
ATOM   2165  H HG13 . ILE A 1 288 ? 118.153 122.421 128.982 1.00 24.22  ?  288 ILE A HG13 1 
ATOM   2166  H HG21 . ILE A 1 288 ? 117.655 125.053 131.265 1.00 24.22  ?  288 ILE A HG21 1 
ATOM   2167  H HG22 . ILE A 1 288 ? 119.071 125.463 130.673 1.00 24.22  ?  288 ILE A HG22 1 
ATOM   2168  H HG23 . ILE A 1 288 ? 118.965 124.855 132.136 1.00 24.22  ?  288 ILE A HG23 1 
ATOM   2169  H HD11 . ILE A 1 288 ? 115.943 122.914 128.912 1.00 24.22  ?  288 ILE A HD11 1 
ATOM   2170  H HD12 . ILE A 1 288 ? 116.264 122.505 130.413 1.00 24.22  ?  288 ILE A HD12 1 
ATOM   2171  H HD13 . ILE A 1 288 ? 116.104 124.037 130.024 1.00 24.22  ?  288 ILE A HD13 1 
ATOM   2172  N N    . LEU A 1 289 ? 122.164 124.316 131.275 1.00 28.24  ?  289 LEU A N    1 
ATOM   2173  C CA   . LEU A 1 289 ? 123.192 124.610 132.272 1.00 28.24  ?  289 LEU A CA   1 
ATOM   2174  C C    . LEU A 1 289 ? 122.786 125.870 133.029 1.00 28.24  ?  289 LEU A C    1 
ATOM   2175  O O    . LEU A 1 289 ? 122.727 126.961 132.456 1.00 28.24  ?  289 LEU A O    1 
ATOM   2176  C CB   . LEU A 1 289 ? 124.554 124.770 131.604 1.00 28.24  ?  289 LEU A CB   1 
ATOM   2177  C CG   . LEU A 1 289 ? 125.696 125.273 132.489 1.00 28.24  ?  289 LEU A CG   1 
ATOM   2178  C CD1  . LEU A 1 289 ? 125.984 124.285 133.608 1.00 28.24  ?  289 LEU A CD1  1 
ATOM   2179  C CD2  . LEU A 1 289 ? 126.943 125.519 131.655 1.00 28.24  ?  289 LEU A CD2  1 
ATOM   2180  H H    . LEU A 1 289 ? 122.279 124.733 130.532 1.00 28.24  ?  289 LEU A H    1 
ATOM   2181  H HA   . LEU A 1 289 ? 123.247 123.877 132.905 1.00 28.24  ?  289 LEU A HA   1 
ATOM   2182  H HB2  . LEU A 1 289 ? 124.823 123.906 131.254 1.00 28.24  ?  289 LEU A HB2  1 
ATOM   2183  H HB3  . LEU A 1 289 ? 124.461 125.397 130.870 1.00 28.24  ?  289 LEU A HB3  1 
ATOM   2184  H HG   . LEU A 1 289 ? 125.440 126.117 132.893 1.00 28.24  ?  289 LEU A HG   1 
ATOM   2185  H HD11 . LEU A 1 289 ? 126.743 124.603 134.121 1.00 28.24  ?  289 LEU A HD11 1 
ATOM   2186  H HD12 . LEU A 1 289 ? 125.203 124.218 134.179 1.00 28.24  ?  289 LEU A HD12 1 
ATOM   2187  H HD13 . LEU A 1 289 ? 126.186 123.419 133.219 1.00 28.24  ?  289 LEU A HD13 1 
ATOM   2188  H HD21 . LEU A 1 289 ? 127.648 125.851 132.233 1.00 28.24  ?  289 LEU A HD21 1 
ATOM   2189  H HD22 . LEU A 1 289 ? 127.217 124.684 131.244 1.00 28.24  ?  289 LEU A HD22 1 
ATOM   2190  H HD23 . LEU A 1 289 ? 126.740 126.174 130.970 1.00 28.24  ?  289 LEU A HD23 1 
ATOM   2191  N N    . PHE A 1 290 ? 122.506 125.714 134.321 1.00 30.84  ?  290 PHE A N    1 
ATOM   2192  C CA   . PHE A 1 290 ? 122.169 126.833 135.194 1.00 30.84  ?  290 PHE A CA   1 
ATOM   2193  C C    . PHE A 1 290 ? 123.407 127.218 135.996 1.00 30.84  ?  290 PHE A C    1 
ATOM   2194  O O    . PHE A 1 290 ? 123.884 126.438 136.828 1.00 30.84  ?  290 PHE A O    1 
ATOM   2195  C CB   . PHE A 1 290 ? 121.013 126.468 136.122 1.00 30.84  ?  290 PHE A CB   1 
ATOM   2196  C CG   . PHE A 1 290 ? 119.649 126.732 135.540 1.00 30.84  ?  290 PHE A CG   1 
ATOM   2197  C CD1  . PHE A 1 290 ? 119.458 126.812 134.170 1.00 30.84  ?  290 PHE A CD1  1 
ATOM   2198  C CD2  . PHE A 1 290 ? 118.556 126.903 136.373 1.00 30.84  ?  290 PHE A CD2  1 
ATOM   2199  C CE1  . PHE A 1 290 ? 118.203 127.057 133.645 1.00 30.84  ?  290 PHE A CE1  1 
ATOM   2200  C CE2  . PHE A 1 290 ? 117.300 127.147 135.853 1.00 30.84  ?  290 PHE A CE2  1 
ATOM   2201  C CZ   . PHE A 1 290 ? 117.124 127.223 134.488 1.00 30.84  ?  290 PHE A CZ   1 
ATOM   2202  H H    . PHE A 1 290 ? 122.504 124.953 134.722 1.00 30.84  ?  290 PHE A H    1 
ATOM   2203  H HA   . PHE A 1 290 ? 121.915 127.601 134.659 1.00 30.84  ?  290 PHE A HA   1 
ATOM   2204  H HB2  . PHE A 1 290 ? 121.068 125.522 136.330 1.00 30.84  ?  290 PHE A HB2  1 
ATOM   2205  H HB3  . PHE A 1 290 ? 121.092 126.988 136.937 1.00 30.84  ?  290 PHE A HB3  1 
ATOM   2206  H HD1  . PHE A 1 290 ? 120.181 126.700 133.596 1.00 30.84  ?  290 PHE A HD1  1 
ATOM   2207  H HD2  . PHE A 1 290 ? 118.669 126.852 137.295 1.00 30.84  ?  290 PHE A HD2  1 
ATOM   2208  H HE1  . PHE A 1 290 ? 118.086 127.107 132.724 1.00 30.84  ?  290 PHE A HE1  1 
ATOM   2209  H HE2  . PHE A 1 290 ? 116.574 127.259 136.424 1.00 30.84  ?  290 PHE A HE2  1 
ATOM   2210  H HZ   . PHE A 1 290 ? 116.278 127.388 134.136 1.00 30.84  ?  290 PHE A HZ   1 
ATOM   2211  N N    . LEU A 1 291 ? 123.927 128.418 135.747 1.00 34.74  ?  291 LEU A N    1 
ATOM   2212  C CA   . LEU A 1 291 ? 125.048 128.960 136.514 1.00 34.74  ?  291 LEU A CA   1 
ATOM   2213  C C    . LEU A 1 291 ? 124.460 129.759 137.670 1.00 34.74  ?  291 LEU A C    1 
ATOM   2214  O O    . LEU A 1 291 ? 124.149 130.944 137.543 1.00 34.74  ?  291 LEU A O    1 
ATOM   2215  C CB   . LEU A 1 291 ? 125.949 129.811 135.629 1.00 34.74  ?  291 LEU A CB   1 
ATOM   2216  C CG   . LEU A 1 291 ? 126.623 129.062 134.477 1.00 34.74  ?  291 LEU A CG   1 
ATOM   2217  C CD1  . LEU A 1 291 ? 126.886 129.997 133.307 1.00 34.74  ?  291 LEU A CD1  1 
ATOM   2218  C CD2  . LEU A 1 291 ? 127.914 128.407 134.944 1.00 34.74  ?  291 LEU A CD2  1 
ATOM   2219  H H    . LEU A 1 291 ? 123.645 128.946 135.129 1.00 34.74  ?  291 LEU A H    1 
ATOM   2220  H HA   . LEU A 1 291 ? 125.575 128.232 136.879 1.00 34.74  ?  291 LEU A HA   1 
ATOM   2221  H HB2  . LEU A 1 291 ? 125.417 130.524 135.243 1.00 34.74  ?  291 LEU A HB2  1 
ATOM   2222  H HB3  . LEU A 1 291 ? 126.651 130.192 136.180 1.00 34.74  ?  291 LEU A HB3  1 
ATOM   2223  H HG   . LEU A 1 291 ? 126.029 128.360 134.169 1.00 34.74  ?  291 LEU A HG   1 
ATOM   2224  H HD11 . LEU A 1 291 ? 126.042 130.358 132.995 1.00 34.74  ?  291 LEU A HD11 1 
ATOM   2225  H HD12 . LEU A 1 291 ? 127.316 129.497 132.595 1.00 34.74  ?  291 LEU A HD12 1 
ATOM   2226  H HD13 . LEU A 1 291 ? 127.465 130.716 133.603 1.00 34.74  ?  291 LEU A HD13 1 
ATOM   2227  H HD21 . LEU A 1 291 ? 127.712 127.792 135.666 1.00 34.74  ?  291 LEU A HD21 1 
ATOM   2228  H HD22 . LEU A 1 291 ? 128.310 127.926 134.200 1.00 34.74  ?  291 LEU A HD22 1 
ATOM   2229  H HD23 . LEU A 1 291 ? 128.523 129.095 135.254 1.00 34.74  ?  291 LEU A HD23 1 
ATOM   2230  N N    . ASN A 1 292 ? 124.306 129.098 138.813 1.00 38.79  ?  292 ASN A N    1 
ATOM   2231  C CA   . ASN A 1 292 ? 123.617 129.663 139.961 1.00 38.79  ?  292 ASN A CA   1 
ATOM   2232  C C    . ASN A 1 292 ? 124.608 130.385 140.873 1.00 38.79  ?  292 ASN A C    1 
ATOM   2233  O O    . ASN A 1 292 ? 125.818 130.400 140.639 1.00 38.79  ?  292 ASN A O    1 
ATOM   2234  C CB   . ASN A 1 292 ? 122.870 128.561 140.717 1.00 38.79  ?  292 ASN A CB   1 
ATOM   2235  C CG   . ASN A 1 292 ? 121.702 129.093 141.525 1.00 38.79  ?  292 ASN A CG   1 
ATOM   2236  O OD1  . ASN A 1 292 ? 121.313 130.253 141.389 1.00 38.79  ?  292 ASN A OD1  1 
ATOM   2237  N ND2  . ASN A 1 292 ? 121.134 128.243 142.372 1.00 38.79  ?  292 ASN A ND2  1 
ATOM   2238  H H    . ASN A 1 292 ? 124.601 128.302 138.949 1.00 38.79  ?  292 ASN A H    1 
ATOM   2239  H HA   . ASN A 1 292 ? 122.966 130.308 139.649 1.00 38.79  ?  292 ASN A HA   1 
ATOM   2240  H HB2  . ASN A 1 292 ? 122.525 127.918 140.078 1.00 38.79  ?  292 ASN A HB2  1 
ATOM   2241  H HB3  . ASN A 1 292 ? 123.484 128.125 141.328 1.00 38.79  ?  292 ASN A HB3  1 
ATOM   2242  H HD21 . ASN A 1 292 ? 121.433 127.440 142.440 1.00 38.79  ?  292 ASN A HD21 1 
ATOM   2243  H HD22 . ASN A 1 292 ? 120.468 128.496 142.854 1.00 38.79  ?  292 ASN A HD22 1 
ATOM   2244  N N    . LYS A 1 293 ? 124.074 130.994 141.933 1.00 43.90  ?  293 LYS A N    1 
ATOM   2245  C CA   . LYS A 1 293 ? 124.883 131.707 142.921 1.00 43.90  ?  293 LYS A CA   1 
ATOM   2246  C C    . LYS A 1 293 ? 125.682 132.834 142.270 1.00 43.90  ?  293 LYS A C    1 
ATOM   2247  O O    . LYS A 1 293 ? 126.857 133.046 142.576 1.00 43.90  ?  293 LYS A O    1 
ATOM   2248  C CB   . LYS A 1 293 ? 125.812 130.744 143.664 1.00 43.90  ?  293 LYS A CB   1 
ATOM   2249  C CG   . LYS A 1 293 ? 125.090 129.599 144.359 1.00 43.90  ?  293 LYS A CG   1 
ATOM   2250  C CD   . LYS A 1 293 ? 124.156 130.100 145.449 1.00 43.90  ?  293 LYS A CD   1 
ATOM   2251  C CE   . LYS A 1 293 ? 123.613 128.953 146.284 1.00 43.90  ?  293 LYS A CE   1 
ATOM   2252  N NZ   . LYS A 1 293 ? 124.643 128.389 147.199 1.00 43.90  1  293 LYS A NZ   1 
ATOM   2253  H H    . LYS A 1 293 ? 123.232 131.012 142.103 1.00 43.90  ?  293 LYS A H    1 
ATOM   2254  H HA   . LYS A 1 293 ? 124.291 132.109 143.575 1.00 43.90  ?  293 LYS A HA   1 
ATOM   2255  H HB2  . LYS A 1 293 ? 126.436 130.358 143.029 1.00 43.90  ?  293 LYS A HB2  1 
ATOM   2256  H HB3  . LYS A 1 293 ? 126.298 131.240 144.341 1.00 43.90  ?  293 LYS A HB3  1 
ATOM   2257  H HG2  . LYS A 1 293 ? 124.562 129.111 143.708 1.00 43.90  ?  293 LYS A HG2  1 
ATOM   2258  H HG3  . LYS A 1 293 ? 125.744 129.011 144.768 1.00 43.90  ?  293 LYS A HG3  1 
ATOM   2259  H HD2  . LYS A 1 293 ? 124.642 130.701 146.035 1.00 43.90  ?  293 LYS A HD2  1 
ATOM   2260  H HD3  . LYS A 1 293 ? 123.406 130.561 145.042 1.00 43.90  ?  293 LYS A HD3  1 
ATOM   2261  H HE2  . LYS A 1 293 ? 122.873 129.274 146.823 1.00 43.90  ?  293 LYS A HE2  1 
ATOM   2262  H HE3  . LYS A 1 293 ? 123.313 128.244 145.694 1.00 43.90  ?  293 LYS A HE3  1 
ATOM   2263  H HZ1  . LYS A 1 293 ? 124.295 127.720 147.673 1.00 43.90  ?  293 LYS A HZ1  1 
ATOM   2264  H HZ2  . LYS A 1 293 ? 124.932 129.019 147.757 1.00 43.90  ?  293 LYS A HZ2  1 
ATOM   2265  H HZ3  . LYS A 1 293 ? 125.332 128.080 146.728 1.00 43.90  ?  293 LYS A HZ3  1 
ATOM   2266  N N    . GLN A 1 294 ? 125.035 133.566 141.360 1.00 42.31  ?  294 GLN A N    1 
ATOM   2267  C CA   . GLN A 1 294 ? 125.714 134.662 140.678 1.00 42.31  ?  294 GLN A CA   1 
ATOM   2268  C C    . GLN A 1 294 ? 126.013 135.820 141.621 1.00 42.31  ?  294 GLN A C    1 
ATOM   2269  O O    . GLN A 1 294 ? 127.062 136.461 141.495 1.00 42.31  ?  294 GLN A O    1 
ATOM   2270  C CB   . GLN A 1 294 ? 124.873 135.145 139.497 1.00 42.31  ?  294 GLN A CB   1 
ATOM   2271  C CG   . GLN A 1 294 ? 124.768 134.137 138.364 1.00 42.31  ?  294 GLN A CG   1 
ATOM   2272  C CD   . GLN A 1 294 ? 126.097 133.887 137.680 1.00 42.31  ?  294 GLN A CD   1 
ATOM   2273  O OE1  . GLN A 1 294 ? 126.598 134.736 136.943 1.00 42.31  ?  294 GLN A OE1  1 
ATOM   2274  N NE2  . GLN A 1 294 ? 126.677 132.718 137.923 1.00 42.31  ?  294 GLN A NE2  1 
ATOM   2275  H H    . GLN A 1 294 ? 124.216 133.449 141.125 1.00 42.31  ?  294 GLN A H    1 
ATOM   2276  H HA   . GLN A 1 294 ? 126.560 134.338 140.331 1.00 42.31  ?  294 GLN A HA   1 
ATOM   2277  H HB2  . GLN A 1 294 ? 123.975 135.335 139.809 1.00 42.31  ?  294 GLN A HB2  1 
ATOM   2278  H HB3  . GLN A 1 294 ? 125.274 135.953 139.138 1.00 42.31  ?  294 GLN A HB3  1 
ATOM   2279  H HG2  . GLN A 1 294 ? 124.453 133.292 138.722 1.00 42.31  ?  294 GLN A HG2  1 
ATOM   2280  H HG3  . GLN A 1 294 ? 124.145 134.470 137.700 1.00 42.31  ?  294 GLN A HG3  1 
ATOM   2281  H HE21 . GLN A 1 294 ? 126.298 132.149 138.444 1.00 42.31  ?  294 GLN A HE21 1 
ATOM   2282  H HE22 . GLN A 1 294 ? 127.433 132.529 137.558 1.00 42.31  ?  294 GLN A HE22 1 
ATOM   2283  N N    . ASP A 1 295 ? 125.110 136.113 142.559 1.00 48.55  ?  295 ASP A N    1 
ATOM   2284  C CA   . ASP A 1 295 ? 125.355 137.196 143.508 1.00 48.55  ?  295 ASP A CA   1 
ATOM   2285  C C    . ASP A 1 295 ? 126.554 136.882 144.396 1.00 48.55  ?  295 ASP A C    1 
ATOM   2286  O O    . ASP A 1 295 ? 127.373 137.762 144.694 1.00 48.55  ?  295 ASP A O    1 
ATOM   2287  C CB   . ASP A 1 295 ? 124.105 137.446 144.353 1.00 48.55  ?  295 ASP A CB   1 
ATOM   2288  C CG   . ASP A 1 295 ? 123.584 136.185 145.014 1.00 48.55  ?  295 ASP A CG   1 
ATOM   2289  O OD1  . ASP A 1 295 ? 124.035 135.870 146.134 1.00 48.55  ?  295 ASP A OD1  1 
ATOM   2290  O OD2  . ASP A 1 295 ? 122.724 135.508 144.412 1.00 48.55  -1 295 ASP A OD2  1 
ATOM   2291  H H    . ASP A 1 295 ? 124.359 135.707 142.661 1.00 48.55  ?  295 ASP A H    1 
ATOM   2292  H HA   . ASP A 1 295 ? 125.552 138.009 143.016 1.00 48.55  ?  295 ASP A HA   1 
ATOM   2293  H HB2  . ASP A 1 295 ? 124.317 138.085 145.051 1.00 48.55  ?  295 ASP A HB2  1 
ATOM   2294  H HB3  . ASP A 1 295 ? 123.403 137.797 143.783 1.00 48.55  ?  295 ASP A HB3  1 
ATOM   2295  N N    . LEU A 1 296 ? 126.667 135.627 144.839 1.00 48.28  ?  296 LEU A N    1 
ATOM   2296  C CA   . LEU A 1 296 ? 127.825 135.231 145.633 1.00 48.28  ?  296 LEU A CA   1 
ATOM   2297  C C    . LEU A 1 296 ? 129.114 135.409 144.843 1.00 48.28  ?  296 LEU A C    1 
ATOM   2298  O O    . LEU A 1 296 ? 130.108 135.918 145.372 1.00 48.28  ?  296 LEU A O    1 
ATOM   2299  C CB   . LEU A 1 296 ? 127.678 133.782 146.096 1.00 48.28  ?  296 LEU A CB   1 
ATOM   2300  C CG   . LEU A 1 296 ? 127.187 133.583 147.532 1.00 48.28  ?  296 LEU A CG   1 
ATOM   2301  C CD1  . LEU A 1 296 ? 125.786 134.143 147.711 1.00 48.28  ?  296 LEU A CD1  1 
ATOM   2302  C CD2  . LEU A 1 296 ? 127.231 132.111 147.912 1.00 48.28  ?  296 LEU A CD2  1 
ATOM   2303  H H    . LEU A 1 296 ? 126.097 135.000 144.694 1.00 48.28  ?  296 LEU A H    1 
ATOM   2304  H HA   . LEU A 1 296 ? 127.871 135.789 146.422 1.00 48.28  ?  296 LEU A HA   1 
ATOM   2305  H HB2  . LEU A 1 296 ? 127.051 133.330 145.509 1.00 48.28  ?  296 LEU A HB2  1 
ATOM   2306  H HB3  . LEU A 1 296 ? 128.546 133.357 146.031 1.00 48.28  ?  296 LEU A HB3  1 
ATOM   2307  H HG   . LEU A 1 296 ? 127.777 134.063 148.134 1.00 48.28  ?  296 LEU A HG   1 
ATOM   2308  H HD11 . LEU A 1 296 ? 125.820 135.109 147.627 1.00 48.28  ?  296 LEU A HD11 1 
ATOM   2309  H HD12 . LEU A 1 296 ? 125.459 133.899 148.591 1.00 48.28  ?  296 LEU A HD12 1 
ATOM   2310  H HD13 . LEU A 1 296 ? 125.207 133.770 147.028 1.00 48.28  ?  296 LEU A HD13 1 
ATOM   2311  H HD21 . LEU A 1 296 ? 126.921 132.011 148.825 1.00 48.28  ?  296 LEU A HD21 1 
ATOM   2312  H HD22 . LEU A 1 296 ? 126.657 131.613 147.310 1.00 48.28  ?  296 LEU A HD22 1 
ATOM   2313  H HD23 . LEU A 1 296 ? 128.145 131.794 147.836 1.00 48.28  ?  296 LEU A HD23 1 
ATOM   2314  N N    . LEU A 1 297 ? 129.115 135.005 143.571 1.00 46.87  ?  297 LEU A N    1 
ATOM   2315  C CA   . LEU A 1 297 ? 130.297 135.197 142.738 1.00 46.87  ?  297 LEU A CA   1 
ATOM   2316  C C    . LEU A 1 297 ? 130.623 136.677 142.588 1.00 46.87  ?  297 LEU A C    1 
ATOM   2317  O O    . LEU A 1 297 ? 131.791 137.076 142.666 1.00 46.87  ?  297 LEU A O    1 
ATOM   2318  C CB   . LEU A 1 297 ? 130.081 134.553 141.368 1.00 46.87  ?  297 LEU A CB   1 
ATOM   2319  C CG   . LEU A 1 297 ? 131.216 134.691 140.349 1.00 46.87  ?  297 LEU A CG   1 
ATOM   2320  C CD1  . LEU A 1 297 ? 132.256 133.602 140.554 1.00 46.87  ?  297 LEU A CD1  1 
ATOM   2321  C CD2  . LEU A 1 297 ? 130.666 134.651 138.932 1.00 46.87  ?  297 LEU A CD2  1 
ATOM   2322  H H    . LEU A 1 297 ? 128.454 134.624 143.174 1.00 46.87  ?  297 LEU A H    1 
ATOM   2323  H HA   . LEU A 1 297 ? 131.056 134.763 143.159 1.00 46.87  ?  297 LEU A HA   1 
ATOM   2324  H HB2  . LEU A 1 297 ? 129.929 133.604 141.500 1.00 46.87  ?  297 LEU A HB2  1 
ATOM   2325  H HB3  . LEU A 1 297 ? 129.290 134.950 140.970 1.00 46.87  ?  297 LEU A HB3  1 
ATOM   2326  H HG   . LEU A 1 297 ? 131.656 135.546 140.469 1.00 46.87  ?  297 LEU A HG   1 
ATOM   2327  H HD11 . LEU A 1 297 ? 132.968 133.719 139.906 1.00 46.87  ?  297 LEU A HD11 1 
ATOM   2328  H HD12 . LEU A 1 297 ? 132.613 133.672 141.454 1.00 46.87  ?  297 LEU A HD12 1 
ATOM   2329  H HD13 . LEU A 1 297 ? 131.835 132.736 140.431 1.00 46.87  ?  297 LEU A HD13 1 
ATOM   2330  H HD21 . LEU A 1 297 ? 131.404 134.719 138.306 1.00 46.87  ?  297 LEU A HD21 1 
ATOM   2331  H HD22 . LEU A 1 297 ? 130.195 133.813 138.800 1.00 46.87  ?  297 LEU A HD22 1 
ATOM   2332  H HD23 . LEU A 1 297 ? 130.057 135.396 138.809 1.00 46.87  ?  297 LEU A HD23 1 
ATOM   2333  N N    . ALA A 1 298 ? 129.601 137.507 142.368 1.00 50.64  ?  298 ALA A N    1 
ATOM   2334  C CA   . ALA A 1 298 ? 129.831 138.936 142.187 1.00 50.64  ?  298 ALA A CA   1 
ATOM   2335  C C    . ALA A 1 298 ? 130.459 139.549 143.431 1.00 50.64  ?  298 ALA A C    1 
ATOM   2336  O O    . ALA A 1 298 ? 131.428 140.311 143.340 1.00 50.64  ?  298 ALA A O    1 
ATOM   2337  C CB   . ALA A 1 298 ? 128.515 139.637 141.846 1.00 50.64  ?  298 ALA A CB   1 
ATOM   2338  H H    . ALA A 1 298 ? 128.777 137.269 142.319 1.00 50.64  ?  298 ALA A H    1 
ATOM   2339  H HA   . ALA A 1 298 ? 130.442 139.067 141.446 1.00 50.64  ?  298 ALA A HA   1 
ATOM   2340  H HB1  . ALA A 1 298 ? 128.684 140.585 141.731 1.00 50.64  ?  298 ALA A HB1  1 
ATOM   2341  H HB2  . ALA A 1 298 ? 127.887 139.498 142.572 1.00 50.64  ?  298 ALA A HB2  1 
ATOM   2342  H HB3  . ALA A 1 298 ? 128.161 139.261 141.025 1.00 50.64  ?  298 ALA A HB3  1 
ATOM   2343  N N    . GLU A 1 299 ? 129.922 139.224 144.609 1.00 52.25  ?  299 GLU A N    1 
ATOM   2344  C CA   . GLU A 1 299 ? 130.495 139.762 145.839 1.00 52.25  ?  299 GLU A CA   1 
ATOM   2345  C C    . GLU A 1 299 ? 131.862 139.163 146.145 1.00 52.25  ?  299 GLU A C    1 
ATOM   2346  O O    . GLU A 1 299 ? 132.667 139.808 146.826 1.00 52.25  ?  299 GLU A O    1 
ATOM   2347  C CB   . GLU A 1 299 ? 129.549 139.529 147.019 1.00 52.25  ?  299 GLU A CB   1 
ATOM   2348  C CG   . GLU A 1 299 ? 129.304 138.071 147.351 1.00 52.25  ?  299 GLU A CG   1 
ATOM   2349  C CD   . GLU A 1 299 ? 128.263 137.889 148.438 1.00 52.25  ?  299 GLU A CD   1 
ATOM   2350  O OE1  . GLU A 1 299 ? 127.866 138.898 149.057 1.00 52.25  ?  299 GLU A OE1  1 
ATOM   2351  O OE2  . GLU A 1 299 ? 127.842 136.737 148.675 1.00 52.25  -1 299 GLU A OE2  1 
ATOM   2352  H H    . GLU A 1 299 ? 129.244 138.708 144.720 1.00 52.25  ?  299 GLU A H    1 
ATOM   2353  H HA   . GLU A 1 299 ? 130.608 140.719 145.736 1.00 52.25  ?  299 GLU A HA   1 
ATOM   2354  H HB2  . GLU A 1 299 ? 129.927 139.950 147.807 1.00 52.25  ?  299 GLU A HB2  1 
ATOM   2355  H HB3  . GLU A 1 299 ? 128.691 139.932 146.814 1.00 52.25  ?  299 GLU A HB3  1 
ATOM   2356  H HG2  . GLU A 1 299 ? 128.986 137.624 146.553 1.00 52.25  ?  299 GLU A HG2  1 
ATOM   2357  H HG3  . GLU A 1 299 ? 130.132 137.667 147.654 1.00 52.25  ?  299 GLU A HG3  1 
ATOM   2358  N N    . LYS A 1 300 ? 132.143 137.951 145.661 1.00 53.78  ?  300 LYS A N    1 
ATOM   2359  C CA   . LYS A 1 300 ? 133.443 137.335 145.895 1.00 53.78  ?  300 LYS A CA   1 
ATOM   2360  C C    . LYS A 1 300 ? 134.533 137.927 145.010 1.00 53.78  ?  300 LYS A C    1 
ATOM   2361  O O    . LYS A 1 300 ? 135.668 138.101 145.469 1.00 53.78  ?  300 LYS A O    1 
ATOM   2362  C CB   . LYS A 1 300 ? 133.350 135.826 145.661 1.00 53.78  ?  300 LYS A CB   1 
ATOM   2363  C CG   . LYS A 1 300 ? 134.576 135.046 146.104 1.00 53.78  ?  300 LYS A CG   1 
ATOM   2364  C CD   . LYS A 1 300 ? 134.276 133.558 146.196 1.00 53.78  ?  300 LYS A CD   1 
ATOM   2365  C CE   . LYS A 1 300 ? 135.479 132.775 146.695 1.00 53.78  ?  300 LYS A CE   1 
ATOM   2366  N NZ   . LYS A 1 300 ? 135.128 131.368 147.033 1.00 53.78  1  300 LYS A NZ   1 
ATOM   2367  H H    . LYS A 1 300 ? 131.600 137.470 145.199 1.00 53.78  ?  300 LYS A H    1 
ATOM   2368  H HA   . LYS A 1 300 ? 133.698 137.479 146.819 1.00 53.78  ?  300 LYS A HA   1 
ATOM   2369  H HB2  . LYS A 1 300 ? 132.588 135.482 146.153 1.00 53.78  ?  300 LYS A HB2  1 
ATOM   2370  H HB3  . LYS A 1 300 ? 133.226 135.666 144.712 1.00 53.78  ?  300 LYS A HB3  1 
ATOM   2371  H HG2  . LYS A 1 300 ? 135.288 135.174 145.459 1.00 53.78  ?  300 LYS A HG2  1 
ATOM   2372  H HG3  . LYS A 1 300 ? 134.854 135.356 146.980 1.00 53.78  ?  300 LYS A HG3  1 
ATOM   2373  H HD2  . LYS A 1 300 ? 133.543 133.417 146.816 1.00 53.78  ?  300 LYS A HD2  1 
ATOM   2374  H HD3  . LYS A 1 300 ? 134.040 133.224 145.316 1.00 53.78  ?  300 LYS A HD3  1 
ATOM   2375  H HE2  . LYS A 1 300 ? 136.156 132.758 146.002 1.00 53.78  ?  300 LYS A HE2  1 
ATOM   2376  H HE3  . LYS A 1 300 ? 135.827 133.200 147.494 1.00 53.78  ?  300 LYS A HE3  1 
ATOM   2377  H HZ1  . LYS A 1 300 ? 135.851 130.934 147.316 1.00 53.78  ?  300 LYS A HZ1  1 
ATOM   2378  H HZ2  . LYS A 1 300 ? 134.806 130.954 146.314 1.00 53.78  ?  300 LYS A HZ2  1 
ATOM   2379  H HZ3  . LYS A 1 300 ? 134.512 131.354 147.675 1.00 53.78  ?  300 LYS A HZ3  1 
ATOM   2380  N N    . VAL A 1 301 ? 134.218 138.242 143.757 1.00 52.27  ?  301 VAL A N    1 
ATOM   2381  C CA   . VAL A 1 301 ? 135.212 138.728 142.807 1.00 52.27  ?  301 VAL A CA   1 
ATOM   2382  C C    . VAL A 1 301 ? 135.315 140.248 142.828 1.00 52.27  ?  301 VAL A C    1 
ATOM   2383  O O    . VAL A 1 301 ? 136.349 140.804 142.455 1.00 52.27  ?  301 VAL A O    1 
ATOM   2384  C CB   . VAL A 1 301 ? 134.895 138.215 141.385 1.00 52.27  ?  301 VAL A CB   1 
ATOM   2385  C CG1  . VAL A 1 301 ? 135.012 136.699 141.330 1.00 52.27  ?  301 VAL A CG1  1 
ATOM   2386  C CG2  . VAL A 1 301 ? 133.516 138.675 140.930 1.00 52.27  ?  301 VAL A CG2  1 
ATOM   2387  H H    . VAL A 1 301 ? 133.425 138.181 143.431 1.00 52.27  ?  301 VAL A H    1 
ATOM   2388  H HA   . VAL A 1 301 ? 136.079 138.373 143.059 1.00 52.27  ?  301 VAL A HA   1 
ATOM   2389  H HB   . VAL A 1 301 ? 135.547 138.584 140.769 1.00 52.27  ?  301 VAL A HB   1 
ATOM   2390  H HG11 . VAL A 1 301 ? 134.956 136.411 140.405 1.00 52.27  ?  301 VAL A HG11 1 
ATOM   2391  H HG12 . VAL A 1 301 ? 135.865 136.435 141.709 1.00 52.27  ?  301 VAL A HG12 1 
ATOM   2392  H HG13 . VAL A 1 301 ? 134.288 136.308 141.844 1.00 52.27  ?  301 VAL A HG13 1 
ATOM   2393  H HG21 . VAL A 1 301 ? 133.612 139.171 140.103 1.00 52.27  ?  301 VAL A HG21 1 
ATOM   2394  H HG22 . VAL A 1 301 ? 132.957 137.897 140.780 1.00 52.27  ?  301 VAL A HG22 1 
ATOM   2395  H HG23 . VAL A 1 301 ? 133.123 139.243 141.611 1.00 52.27  ?  301 VAL A HG23 1 
ATOM   2396  N N    . LEU A 1 302 ? 134.255 140.937 143.256 1.00 56.28  ?  302 LEU A N    1 
ATOM   2397  C CA   . LEU A 1 302 ? 134.303 142.394 143.311 1.00 56.28  ?  302 LEU A CA   1 
ATOM   2398  C C    . LEU A 1 302 ? 135.391 142.870 144.265 1.00 56.28  ?  302 LEU A C    1 
ATOM   2399  O O    . LEU A 1 302 ? 136.130 143.813 143.957 1.00 56.28  ?  302 LEU A O    1 
ATOM   2400  C CB   . LEU A 1 302 ? 132.941 142.949 143.729 1.00 56.28  ?  302 LEU A CB   1 
ATOM   2401  C CG   . LEU A 1 302 ? 132.784 144.469 143.652 1.00 56.28  ?  302 LEU A CG   1 
ATOM   2402  C CD1  . LEU A 1 302 ? 132.677 144.925 142.204 1.00 56.28  ?  302 LEU A CD1  1 
ATOM   2403  C CD2  . LEU A 1 302 ? 131.571 144.922 144.449 1.00 56.28  ?  302 LEU A CD2  1 
ATOM   2404  H H    . LEU A 1 302 ? 133.512 140.591 143.515 1.00 56.28  ?  302 LEU A H    1 
ATOM   2405  H HA   . LEU A 1 302 ? 134.509 142.737 142.427 1.00 56.28  ?  302 LEU A HA   1 
ATOM   2406  H HB2  . LEU A 1 302 ? 132.265 142.562 143.153 1.00 56.28  ?  302 LEU A HB2  1 
ATOM   2407  H HB3  . LEU A 1 302 ? 132.772 142.686 144.648 1.00 56.28  ?  302 LEU A HB3  1 
ATOM   2408  H HG   . LEU A 1 302 ? 133.568 144.889 144.039 1.00 56.28  ?  302 LEU A HG   1 
ATOM   2409  H HD11 . LEU A 1 302 ? 133.496 144.693 141.739 1.00 56.28  ?  302 LEU A HD11 1 
ATOM   2410  H HD12 . LEU A 1 302 ? 131.922 144.481 141.788 1.00 56.28  ?  302 LEU A HD12 1 
ATOM   2411  H HD13 . LEU A 1 302 ? 132.547 145.887 142.186 1.00 56.28  ?  302 LEU A HD13 1 
ATOM   2412  H HD21 . LEU A 1 302 ? 131.691 144.669 145.378 1.00 56.28  ?  302 LEU A HD21 1 
ATOM   2413  H HD22 . LEU A 1 302 ? 131.488 145.886 144.377 1.00 56.28  ?  302 LEU A HD22 1 
ATOM   2414  H HD23 . LEU A 1 302 ? 130.779 144.494 144.089 1.00 56.28  ?  302 LEU A HD23 1 
ATOM   2415  N N    . ALA A 1 303 ? 135.506 142.230 145.427 1.00 55.27  ?  303 ALA A N    1 
ATOM   2416  C CA   . ALA A 1 303 ? 136.545 142.572 146.395 1.00 55.27  ?  303 ALA A CA   1 
ATOM   2417  C C    . ALA A 1 303 ? 136.798 141.346 147.259 1.00 55.27  ?  303 ALA A C    1 
ATOM   2418  O O    . ALA A 1 303 ? 135.971 141.005 148.109 1.00 55.27  ?  303 ALA A O    1 
ATOM   2419  C CB   . ALA A 1 303 ? 136.133 143.770 147.246 1.00 55.27  ?  303 ALA A CB   1 
ATOM   2420  H H    . ALA A 1 303 ? 134.991 141.590 145.679 1.00 55.27  ?  303 ALA A H    1 
ATOM   2421  H HA   . ALA A 1 303 ? 137.365 142.794 145.926 1.00 55.27  ?  303 ALA A HA   1 
ATOM   2422  H HB1  . ALA A 1 303 ? 136.844 143.969 147.875 1.00 55.27  ?  303 ALA A HB1  1 
ATOM   2423  H HB2  . ALA A 1 303 ? 135.981 144.532 146.665 1.00 55.27  ?  303 ALA A HB2  1 
ATOM   2424  H HB3  . ALA A 1 303 ? 135.318 143.552 147.725 1.00 55.27  ?  303 ALA A HB3  1 
ATOM   2425  N N    . GLY A 1 304 ? 137.931 140.691 147.043 1.00 58.42  ?  304 GLY A N    1 
ATOM   2426  C CA   . GLY A 1 304 ? 138.263 139.508 147.812 1.00 58.42  ?  304 GLY A CA   1 
ATOM   2427  C C    . GLY A 1 304 ? 139.631 138.992 147.423 1.00 58.42  ?  304 GLY A C    1 
ATOM   2428  O O    . GLY A 1 304 ? 140.198 139.375 146.394 1.00 58.42  ?  304 GLY A O    1 
ATOM   2429  H H    . GLY A 1 304 ? 138.521 140.913 146.458 1.00 58.42  ?  304 GLY A H    1 
ATOM   2430  H HA2  . GLY A 1 304 ? 138.265 139.720 148.758 1.00 58.42  ?  304 GLY A HA2  1 
ATOM   2431  H HA3  . GLY A 1 304 ? 137.607 138.813 147.646 1.00 58.42  ?  304 GLY A HA3  1 
ATOM   2432  N N    . LYS A 1 305 ? 140.153 138.108 148.274 1.00 62.31  ?  305 LYS A N    1 
ATOM   2433  C CA   . LYS A 1 305 ? 141.464 137.512 148.056 1.00 62.31  ?  305 LYS A CA   1 
ATOM   2434  C C    . LYS A 1 305 ? 141.402 136.199 147.286 1.00 62.31  ?  305 LYS A C    1 
ATOM   2435  O O    . LYS A 1 305 ? 142.457 135.629 146.985 1.00 62.31  ?  305 LYS A O    1 
ATOM   2436  C CB   . LYS A 1 305 ? 142.161 137.281 149.399 1.00 62.31  ?  305 LYS A CB   1 
ATOM   2437  C CG   . LYS A 1 305 ? 142.378 138.550 150.208 1.00 62.31  ?  305 LYS A CG   1 
ATOM   2438  C CD   . LYS A 1 305 ? 143.090 138.261 151.518 1.00 62.31  ?  305 LYS A CD   1 
ATOM   2439  C CE   . LYS A 1 305 ? 143.209 139.514 152.372 1.00 62.31  ?  305 LYS A CE   1 
ATOM   2440  N NZ   . LYS A 1 305 ? 143.853 139.238 153.686 1.00 62.31  1  305 LYS A NZ   1 
ATOM   2441  H H    . LYS A 1 305 ? 139.761 137.837 148.990 1.00 62.31  ?  305 LYS A H    1 
ATOM   2442  H HA   . LYS A 1 305 ? 142.007 138.131 147.543 1.00 62.31  ?  305 LYS A HA   1 
ATOM   2443  H HB2  . LYS A 1 305 ? 141.619 136.679 149.932 1.00 62.31  ?  305 LYS A HB2  1 
ATOM   2444  H HB3  . LYS A 1 305 ? 143.030 136.883 149.235 1.00 62.31  ?  305 LYS A HB3  1 
ATOM   2445  H HG2  . LYS A 1 305 ? 142.922 139.167 149.695 1.00 62.31  ?  305 LYS A HG2  1 
ATOM   2446  H HG3  . LYS A 1 305 ? 141.518 138.950 150.411 1.00 62.31  ?  305 LYS A HG3  1 
ATOM   2447  H HD2  . LYS A 1 305 ? 142.588 137.599 152.018 1.00 62.31  ?  305 LYS A HD2  1 
ATOM   2448  H HD3  . LYS A 1 305 ? 143.984 137.935 151.332 1.00 62.31  ?  305 LYS A HD3  1 
ATOM   2449  H HE2  . LYS A 1 305 ? 143.749 140.169 151.903 1.00 62.31  ?  305 LYS A HE2  1 
ATOM   2450  H HE3  . LYS A 1 305 ? 142.322 139.870 152.539 1.00 62.31  ?  305 LYS A HE3  1 
ATOM   2451  H HZ1  . LYS A 1 305 ? 143.908 139.988 154.161 1.00 62.31  ?  305 LYS A HZ1  1 
ATOM   2452  H HZ2  . LYS A 1 305 ? 144.672 138.913 153.561 1.00 62.31  ?  305 LYS A HZ2  1 
ATOM   2453  H HZ3  . LYS A 1 305 ? 143.372 138.642 154.141 1.00 62.31  ?  305 LYS A HZ3  1 
ATOM   2454  N N    . SER A 1 306 ? 140.206 135.707 146.963 1.00 59.51  ?  306 SER A N    1 
ATOM   2455  C CA   . SER A 1 306 ? 140.049 134.435 146.258 1.00 59.51  ?  306 SER A CA   1 
ATOM   2456  C C    . SER A 1 306 ? 140.330 134.660 144.775 1.00 59.51  ?  306 SER A C    1 
ATOM   2457  O O    . SER A 1 306 ? 139.440 134.938 143.968 1.00 59.51  ?  306 SER A O    1 
ATOM   2458  C CB   . SER A 1 306 ? 138.655 133.865 146.485 1.00 59.51  ?  306 SER A CB   1 
ATOM   2459  O OG   . SER A 1 306 ? 137.657 134.770 146.046 1.00 59.51  ?  306 SER A OG   1 
ATOM   2460  H H    . SER A 1 306 ? 139.460 136.095 147.143 1.00 59.51  ?  306 SER A H    1 
ATOM   2461  H HA   . SER A 1 306 ? 140.697 133.798 146.598 1.00 59.51  ?  306 SER A HA   1 
ATOM   2462  H HB2  . SER A 1 306 ? 138.569 133.036 145.988 1.00 59.51  ?  306 SER A HB2  1 
ATOM   2463  H HB3  . SER A 1 306 ? 138.533 133.696 147.433 1.00 59.51  ?  306 SER A HB3  1 
ATOM   2464  H HG   . SER A 1 306 ? 137.735 134.907 145.221 1.00 59.51  ?  306 SER A HG   1 
ATOM   2465  N N    . LYS A 1 307 ? 141.605 134.535 144.415 1.00 59.85  ?  307 LYS A N    1 
ATOM   2466  C CA   . LYS A 1 307 ? 142.012 134.711 143.027 1.00 59.85  ?  307 LYS A CA   1 
ATOM   2467  C C    . LYS A 1 307 ? 141.571 133.515 142.194 1.00 59.85  ?  307 LYS A C    1 
ATOM   2468  O O    . LYS A 1 307 ? 141.800 132.362 142.575 1.00 59.85  ?  307 LYS A O    1 
ATOM   2469  C CB   . LYS A 1 307 ? 143.528 134.889 142.945 1.00 59.85  ?  307 LYS A CB   1 
ATOM   2470  C CG   . LYS A 1 307 ? 144.055 136.147 143.626 1.00 59.85  ?  307 LYS A CG   1 
ATOM   2471  C CD   . LYS A 1 307 ? 143.611 137.419 142.910 1.00 59.85  ?  307 LYS A CD   1 
ATOM   2472  C CE   . LYS A 1 307 ? 143.235 138.519 143.892 1.00 59.85  ?  307 LYS A CE   1 
ATOM   2473  N NZ   . LYS A 1 307 ? 142.339 139.534 143.276 1.00 59.85  1  307 LYS A NZ   1 
ATOM   2474  H H    . LYS A 1 307 ? 142.250 134.350 144.953 1.00 59.85  ?  307 LYS A H    1 
ATOM   2475  H HA   . LYS A 1 307 ? 141.584 135.502 142.667 1.00 59.85  ?  307 LYS A HA   1 
ATOM   2476  H HB2  . LYS A 1 307 ? 143.953 134.127 143.368 1.00 59.85  ?  307 LYS A HB2  1 
ATOM   2477  H HB3  . LYS A 1 307 ? 143.785 134.930 142.011 1.00 59.85  ?  307 LYS A HB3  1 
ATOM   2478  H HG2  . LYS A 1 307 ? 143.724 136.175 144.537 1.00 59.85  ?  307 LYS A HG2  1 
ATOM   2479  H HG3  . LYS A 1 307 ? 145.025 136.125 143.626 1.00 59.85  ?  307 LYS A HG3  1 
ATOM   2480  H HD2  . LYS A 1 307 ? 144.341 137.744 142.361 1.00 59.85  ?  307 LYS A HD2  1 
ATOM   2481  H HD3  . LYS A 1 307 ? 142.839 137.230 142.356 1.00 59.85  ?  307 LYS A HD3  1 
ATOM   2482  H HE2  . LYS A 1 307 ? 142.768 138.130 144.648 1.00 59.85  ?  307 LYS A HE2  1 
ATOM   2483  H HE3  . LYS A 1 307 ? 144.041 138.968 144.192 1.00 59.85  ?  307 LYS A HE3  1 
ATOM   2484  H HZ1  . LYS A 1 307 ? 142.141 140.166 143.871 1.00 59.85  ?  307 LYS A HZ1  1 
ATOM   2485  H HZ2  . LYS A 1 307 ? 142.741 139.911 142.577 1.00 59.85  ?  307 LYS A HZ2  1 
ATOM   2486  H HZ3  . LYS A 1 307 ? 141.585 139.148 143.002 1.00 59.85  ?  307 LYS A HZ3  1 
ATOM   2487  N N    . ILE A 1 308 ? 140.935 133.792 141.054 1.00 52.88  ?  308 ILE A N    1 
ATOM   2488  C CA   . ILE A 1 308 ? 140.508 132.718 140.162 1.00 52.88  ?  308 ILE A CA   1 
ATOM   2489  C C    . ILE A 1 308 ? 141.709 132.062 139.498 1.00 52.88  ?  308 ILE A C    1 
ATOM   2490  O O    . ILE A 1 308 ? 141.741 130.837 139.323 1.00 52.88  ?  308 ILE A O    1 
ATOM   2491  C CB   . ILE A 1 308 ? 139.514 133.256 139.113 1.00 52.88  ?  308 ILE A CB   1 
ATOM   2492  C CG1  . ILE A 1 308 ? 138.246 133.778 139.797 1.00 52.88  ?  308 ILE A CG1  1 
ATOM   2493  C CG2  . ILE A 1 308 ? 139.168 132.167 138.105 1.00 52.88  ?  308 ILE A CG2  1 
ATOM   2494  C CD1  . ILE A 1 308 ? 138.318 135.237 140.202 1.00 52.88  ?  308 ILE A CD1  1 
ATOM   2495  H H    . ILE A 1 308 ? 140.743 134.583 140.778 1.00 52.88  ?  308 ILE A H    1 
ATOM   2496  H HA   . ILE A 1 308 ? 140.052 132.040 140.684 1.00 52.88  ?  308 ILE A HA   1 
ATOM   2497  H HB   . ILE A 1 308 ? 139.935 133.990 138.639 1.00 52.88  ?  308 ILE A HB   1 
ATOM   2498  H HG12 . ILE A 1 308 ? 137.495 133.677 139.191 1.00 52.88  ?  308 ILE A HG12 1 
ATOM   2499  H HG13 . ILE A 1 308 ? 138.089 133.257 140.599 1.00 52.88  ?  308 ILE A HG13 1 
ATOM   2500  H HG21 . ILE A 1 308 ? 139.913 132.051 137.494 1.00 52.88  ?  308 ILE A HG21 1 
ATOM   2501  H HG22 . ILE A 1 308 ? 138.377 132.430 137.609 1.00 52.88  ?  308 ILE A HG22 1 
ATOM   2502  H HG23 . ILE A 1 308 ? 138.998 131.339 138.581 1.00 52.88  ?  308 ILE A HG23 1 
ATOM   2503  H HD11 . ILE A 1 308 ? 138.756 135.306 141.065 1.00 52.88  ?  308 ILE A HD11 1 
ATOM   2504  H HD12 . ILE A 1 308 ? 137.416 135.590 140.260 1.00 52.88  ?  308 ILE A HD12 1 
ATOM   2505  H HD13 . ILE A 1 308 ? 138.820 135.729 139.533 1.00 52.88  ?  308 ILE A HD13 1 
ATOM   2506  N N    . GLU A 1 309 ? 142.712 132.856 139.113 1.00 54.78  ?  309 GLU A N    1 
ATOM   2507  C CA   . GLU A 1 309 ? 143.878 132.307 138.432 1.00 54.78  ?  309 GLU A CA   1 
ATOM   2508  C C    . GLU A 1 309 ? 144.617 131.282 139.281 1.00 54.78  ?  309 GLU A C    1 
ATOM   2509  O O    . GLU A 1 309 ? 145.292 130.409 138.726 1.00 54.78  ?  309 GLU A O    1 
ATOM   2510  C CB   . GLU A 1 309 ? 144.842 133.427 138.029 1.00 54.78  ?  309 GLU A CB   1 
ATOM   2511  C CG   . GLU A 1 309 ? 145.236 134.376 139.158 1.00 54.78  ?  309 GLU A CG   1 
ATOM   2512  C CD   . GLU A 1 309 ? 144.282 135.547 139.316 1.00 54.78  ?  309 GLU A CD   1 
ATOM   2513  O OE1  . GLU A 1 309 ? 143.292 135.621 138.559 1.00 54.78  ?  309 GLU A OE1  1 
ATOM   2514  O OE2  . GLU A 1 309 ? 144.526 136.397 140.198 1.00 54.78  -1 309 GLU A OE2  1 
ATOM   2515  H H    . GLU A 1 309 ? 142.731 133.704 139.233 1.00 54.78  ?  309 GLU A H    1 
ATOM   2516  H HA   . GLU A 1 309 ? 143.585 131.863 137.621 1.00 54.78  ?  309 GLU A HA   1 
ATOM   2517  H HB2  . GLU A 1 309 ? 145.656 133.024 137.689 1.00 54.78  ?  309 GLU A HB2  1 
ATOM   2518  H HB3  . GLU A 1 309 ? 144.427 133.954 137.328 1.00 54.78  ?  309 GLU A HB3  1 
ATOM   2519  H HG2  . GLU A 1 309 ? 145.244 133.884 139.994 1.00 54.78  ?  309 GLU A HG2  1 
ATOM   2520  H HG3  . GLU A 1 309 ? 146.120 134.732 138.977 1.00 54.78  ?  309 GLU A HG3  1 
ATOM   2521  N N    . ASP A 1 310 ? 144.507 131.365 140.609 1.00 57.11  ?  310 ASP A N    1 
ATOM   2522  C CA   . ASP A 1 310 ? 145.161 130.381 141.463 1.00 57.11  ?  310 ASP A CA   1 
ATOM   2523  C C    . ASP A 1 310 ? 144.610 128.981 141.226 1.00 57.11  ?  310 ASP A C    1 
ATOM   2524  O O    . ASP A 1 310 ? 145.324 127.993 141.431 1.00 57.11  ?  310 ASP A O    1 
ATOM   2525  C CB   . ASP A 1 310 ? 145.000 130.772 142.932 1.00 57.11  ?  310 ASP A CB   1 
ATOM   2526  C CG   . ASP A 1 310 ? 145.790 132.014 143.294 1.00 57.11  ?  310 ASP A CG   1 
ATOM   2527  O OD1  . ASP A 1 310 ? 146.515 132.536 142.421 1.00 57.11  ?  310 ASP A OD1  1 
ATOM   2528  O OD2  . ASP A 1 310 ? 145.687 132.469 144.453 1.00 57.11  -1 310 ASP A OD2  1 
ATOM   2529  H H    . ASP A 1 310 ? 144.066 131.971 141.031 1.00 57.11  ?  310 ASP A H    1 
ATOM   2530  H HA   . ASP A 1 310 ? 146.109 130.367 141.259 1.00 57.11  ?  310 ASP A HA   1 
ATOM   2531  H HB2  . ASP A 1 310 ? 144.063 130.950 143.111 1.00 57.11  ?  310 ASP A HB2  1 
ATOM   2532  H HB3  . ASP A 1 310 ? 145.313 130.043 143.490 1.00 57.11  ?  310 ASP A HB3  1 
ATOM   2533  N N    . TYR A 1 311 ? 143.354 128.876 140.796 1.00 54.57  ?  311 TYR A N    1 
ATOM   2534  C CA   . TYR A 1 311 ? 142.729 127.591 140.510 1.00 54.57  ?  311 TYR A CA   1 
ATOM   2535  C C    . TYR A 1 311 ? 142.464 127.375 139.028 1.00 54.57  ?  311 TYR A C    1 
ATOM   2536  O O    . TYR A 1 311 ? 142.265 126.231 138.608 1.00 54.57  ?  311 TYR A O    1 
ATOM   2537  C CB   . TYR A 1 311 ? 141.410 127.467 141.280 1.00 54.57  ?  311 TYR A CB   1 
ATOM   2538  C CG   . TYR A 1 311 ? 141.512 127.913 142.720 1.00 54.57  ?  311 TYR A CG   1 
ATOM   2539  C CD1  . TYR A 1 311 ? 142.226 127.167 143.649 1.00 54.57  ?  311 TYR A CD1  1 
ATOM   2540  C CD2  . TYR A 1 311 ? 140.904 129.084 143.151 1.00 54.57  ?  311 TYR A CD2  1 
ATOM   2541  C CE1  . TYR A 1 311 ? 142.327 127.572 144.966 1.00 54.57  ?  311 TYR A CE1  1 
ATOM   2542  C CE2  . TYR A 1 311 ? 140.999 129.497 144.466 1.00 54.57  ?  311 TYR A CE2  1 
ATOM   2543  C CZ   . TYR A 1 311 ? 141.712 128.738 145.369 1.00 54.57  ?  311 TYR A CZ   1 
ATOM   2544  O OH   . TYR A 1 311 ? 141.809 129.145 146.680 1.00 54.57  ?  311 TYR A OH   1 
ATOM   2545  H H    . TYR A 1 311 ? 142.835 129.549 140.661 1.00 54.57  ?  311 TYR A H    1 
ATOM   2546  H HA   . TYR A 1 311 ? 143.314 126.880 140.812 1.00 54.57  ?  311 TYR A HA   1 
ATOM   2547  H HB2  . TYR A 1 311 ? 140.738 128.016 140.845 1.00 54.57  ?  311 TYR A HB2  1 
ATOM   2548  H HB3  . TYR A 1 311 ? 141.130 126.538 141.275 1.00 54.57  ?  311 TYR A HB3  1 
ATOM   2549  H HD1  . TYR A 1 311 ? 142.642 126.380 143.380 1.00 54.57  ?  311 TYR A HD1  1 
ATOM   2550  H HD2  . TYR A 1 311 ? 140.423 129.599 142.543 1.00 54.57  ?  311 TYR A HD2  1 
ATOM   2551  H HE1  . TYR A 1 311 ? 142.807 127.061 145.577 1.00 54.57  ?  311 TYR A HE1  1 
ATOM   2552  H HE2  . TYR A 1 311 ? 140.585 130.284 144.740 1.00 54.57  ?  311 TYR A HE2  1 
ATOM   2553  H HH   . TYR A 1 311 ? 141.389 129.864 146.789 1.00 54.57  ?  311 TYR A HH   1 
ATOM   2554  N N    . PHE A 1 312 ? 142.444 128.444 138.233 1.00 48.21  ?  312 PHE A N    1 
ATOM   2555  C CA   . PHE A 1 312 ? 142.284 128.348 136.783 1.00 48.21  ?  312 PHE A CA   1 
ATOM   2556  C C    . PHE A 1 312 ? 143.338 129.232 136.130 1.00 48.21  ?  312 PHE A C    1 
ATOM   2557  O O    . PHE A 1 312 ? 143.077 130.398 135.808 1.00 48.21  ?  312 PHE A O    1 
ATOM   2558  C CB   . PHE A 1 312 ? 140.876 128.755 136.349 1.00 48.21  ?  312 PHE A CB   1 
ATOM   2559  C CG   . PHE A 1 312 ? 139.817 127.762 136.729 1.00 48.21  ?  312 PHE A CG   1 
ATOM   2560  C CD1  . PHE A 1 312 ? 139.682 126.573 136.030 1.00 48.21  ?  312 PHE A CD1  1 
ATOM   2561  C CD2  . PHE A 1 312 ? 138.959 128.012 137.786 1.00 48.21  ?  312 PHE A CD2  1 
ATOM   2562  C CE1  . PHE A 1 312 ? 138.710 125.655 136.377 1.00 48.21  ?  312 PHE A CE1  1 
ATOM   2563  C CE2  . PHE A 1 312 ? 137.985 127.097 138.137 1.00 48.21  ?  312 PHE A CE2  1 
ATOM   2564  C CZ   . PHE A 1 312 ? 137.861 125.917 137.432 1.00 48.21  ?  312 PHE A CZ   1 
ATOM   2565  H H    . PHE A 1 312 ? 142.524 129.252 138.516 1.00 48.21  ?  312 PHE A H    1 
ATOM   2566  H HA   . PHE A 1 312 ? 142.422 127.431 136.503 1.00 48.21  ?  312 PHE A HA   1 
ATOM   2567  H HB2  . PHE A 1 312 ? 140.652 129.602 136.767 1.00 48.21  ?  312 PHE A HB2  1 
ATOM   2568  H HB3  . PHE A 1 312 ? 140.862 128.851 135.384 1.00 48.21  ?  312 PHE A HB3  1 
ATOM   2569  H HD1  . PHE A 1 312 ? 140.252 126.392 135.318 1.00 48.21  ?  312 PHE A HD1  1 
ATOM   2570  H HD2  . PHE A 1 312 ? 139.038 128.805 138.264 1.00 48.21  ?  312 PHE A HD2  1 
ATOM   2571  H HE1  . PHE A 1 312 ? 138.629 124.861 135.900 1.00 48.21  ?  312 PHE A HE1  1 
ATOM   2572  H HE2  . PHE A 1 312 ? 137.414 127.276 138.848 1.00 48.21  ?  312 PHE A HE2  1 
ATOM   2573  H HZ   . PHE A 1 312 ? 137.206 125.300 137.667 1.00 48.21  ?  312 PHE A HZ   1 
ATOM   2574  N N    . PRO A 1 313 ? 144.548 128.706 135.912 1.00 48.77  ?  313 PRO A N    1 
ATOM   2575  C CA   . PRO A 1 313 ? 145.633 129.563 135.405 1.00 48.77  ?  313 PRO A CA   1 
ATOM   2576  C C    . PRO A 1 313 ? 145.336 130.198 134.058 1.00 48.77  ?  313 PRO A C    1 
ATOM   2577  O O    . PRO A 1 313 ? 145.903 131.256 133.758 1.00 48.77  ?  313 PRO A O    1 
ATOM   2578  C CB   . PRO A 1 313 ? 146.829 128.604 135.320 1.00 48.77  ?  313 PRO A CB   1 
ATOM   2579  C CG   . PRO A 1 313 ? 146.223 127.250 135.203 1.00 48.77  ?  313 PRO A CG   1 
ATOM   2580  C CD   . PRO A 1 313 ? 144.971 127.299 136.026 1.00 48.77  ?  313 PRO A CD   1 
ATOM   2581  H HA   . PRO A 1 313 ? 145.832 130.261 136.048 1.00 48.77  ?  313 PRO A HA   1 
ATOM   2582  H HB2  . PRO A 1 313 ? 147.361 128.812 134.536 1.00 48.77  ?  313 PRO A HB2  1 
ATOM   2583  H HB3  . PRO A 1 313 ? 147.363 128.674 136.127 1.00 48.77  ?  313 PRO A HB3  1 
ATOM   2584  H HG2  . PRO A 1 313 ? 146.015 127.066 134.274 1.00 48.77  ?  313 PRO A HG2  1 
ATOM   2585  H HG3  . PRO A 1 313 ? 146.837 126.587 135.555 1.00 48.77  ?  313 PRO A HG3  1 
ATOM   2586  H HD2  . PRO A 1 313 ? 144.301 126.708 135.648 1.00 48.77  ?  313 PRO A HD2  1 
ATOM   2587  H HD3  . PRO A 1 313 ? 145.163 127.076 136.950 1.00 48.77  ?  313 PRO A HD3  1 
ATOM   2588  N N    . GLU A 1 314 ? 144.472 129.596 133.239 1.00 46.89  ?  314 GLU A N    1 
ATOM   2589  C CA   . GLU A 1 314 ? 144.138 130.190 131.950 1.00 46.89  ?  314 GLU A CA   1 
ATOM   2590  C C    . GLU A 1 314 ? 143.341 131.480 132.097 1.00 46.89  ?  314 GLU A C    1 
ATOM   2591  O O    . GLU A 1 314 ? 143.181 132.210 131.114 1.00 46.89  ?  314 GLU A O    1 
ATOM   2592  C CB   . GLU A 1 314 ? 143.353 129.192 131.093 1.00 46.89  ?  314 GLU A CB   1 
ATOM   2593  C CG   . GLU A 1 314 ? 142.071 128.675 131.734 1.00 46.89  ?  314 GLU A CG   1 
ATOM   2594  C CD   . GLU A 1 314 ? 142.281 127.391 132.513 1.00 46.89  ?  314 GLU A CD   1 
ATOM   2595  O OE1  . GLU A 1 314 ? 143.099 127.393 133.457 1.00 46.89  ?  314 GLU A OE1  1 
ATOM   2596  O OE2  . GLU A 1 314 ? 141.627 126.380 132.183 1.00 46.89  -1 314 GLU A OE2  1 
ATOM   2597  H H    . GLU A 1 314 ? 144.075 128.853 133.407 1.00 46.89  ?  314 GLU A H    1 
ATOM   2598  H HA   . GLU A 1 314 ? 144.960 130.402 131.481 1.00 46.89  ?  314 GLU A HA   1 
ATOM   2599  H HB2  . GLU A 1 314 ? 143.112 129.624 130.259 1.00 46.89  ?  314 GLU A HB2  1 
ATOM   2600  H HB3  . GLU A 1 314 ? 143.921 128.427 130.912 1.00 46.89  ?  314 GLU A HB3  1 
ATOM   2601  H HG2  . GLU A 1 314 ? 141.727 129.343 132.347 1.00 46.89  ?  314 GLU A HG2  1 
ATOM   2602  H HG3  . GLU A 1 314 ? 141.419 128.499 131.037 1.00 46.89  ?  314 GLU A HG3  1 
ATOM   2603  N N    . PHE A 1 315 ? 142.837 131.776 133.298 1.00 47.46  ?  315 PHE A N    1 
ATOM   2604  C CA   . PHE A 1 315 ? 142.074 133.003 133.499 1.00 47.46  ?  315 PHE A CA   1 
ATOM   2605  C C    . PHE A 1 315 ? 142.939 134.241 133.309 1.00 47.46  ?  315 PHE A C    1 
ATOM   2606  O O    . PHE A 1 315 ? 142.449 135.273 132.836 1.00 47.46  ?  315 PHE A O    1 
ATOM   2607  C CB   . PHE A 1 315 ? 141.448 133.005 134.894 1.00 47.46  ?  315 PHE A CB   1 
ATOM   2608  C CG   . PHE A 1 315 ? 140.552 134.183 135.154 1.00 47.46  ?  315 PHE A CG   1 
ATOM   2609  C CD1  . PHE A 1 315 ? 139.365 134.334 134.460 1.00 47.46  ?  315 PHE A CD1  1 
ATOM   2610  C CD2  . PHE A 1 315 ? 140.898 135.137 136.096 1.00 47.46  ?  315 PHE A CD2  1 
ATOM   2611  C CE1  . PHE A 1 315 ? 138.539 135.415 134.698 1.00 47.46  ?  315 PHE A CE1  1 
ATOM   2612  C CE2  . PHE A 1 315 ? 140.076 136.221 136.338 1.00 47.46  ?  315 PHE A CE2  1 
ATOM   2613  C CZ   . PHE A 1 315 ? 138.895 136.360 135.638 1.00 47.46  ?  315 PHE A CZ   1 
ATOM   2614  H H    . PHE A 1 315 ? 142.922 131.289 134.002 1.00 47.46  ?  315 PHE A H    1 
ATOM   2615  H HA   . PHE A 1 315 ? 141.355 133.037 132.848 1.00 47.46  ?  315 PHE A HA   1 
ATOM   2616  H HB2  . PHE A 1 315 ? 140.917 132.200 135.000 1.00 47.46  ?  315 PHE A HB2  1 
ATOM   2617  H HB3  . PHE A 1 315 ? 142.157 133.020 135.555 1.00 47.46  ?  315 PHE A HB3  1 
ATOM   2618  H HD1  . PHE A 1 315 ? 139.121 133.700 133.825 1.00 47.46  ?  315 PHE A HD1  1 
ATOM   2619  H HD2  . PHE A 1 315 ? 141.693 135.048 136.570 1.00 47.46  ?  315 PHE A HD2  1 
ATOM   2620  H HE1  . PHE A 1 315 ? 137.743 135.507 134.225 1.00 47.46  ?  315 PHE A HE1  1 
ATOM   2621  H HE2  . PHE A 1 315 ? 140.318 136.856 136.973 1.00 47.46  ?  315 PHE A HE2  1 
ATOM   2622  H HZ   . PHE A 1 315 ? 138.340 137.089 135.800 1.00 47.46  ?  315 PHE A HZ   1 
ATOM   2623  N N    . ALA A 1 316 ? 144.222 134.162 133.669 1.00 48.62  ?  316 ALA A N    1 
ATOM   2624  C CA   . ALA A 1 316 ? 145.107 135.315 133.555 1.00 48.62  ?  316 ALA A CA   1 
ATOM   2625  C C    . ALA A 1 316 ? 145.282 135.785 132.118 1.00 48.62  ?  316 ALA A C    1 
ATOM   2626  O O    . ALA A 1 316 ? 145.661 136.943 131.907 1.00 48.62  ?  316 ALA A O    1 
ATOM   2627  C CB   . ALA A 1 316 ? 146.474 134.983 134.156 1.00 48.62  ?  316 ALA A CB   1 
ATOM   2628  H H    . ALA A 1 316 ? 144.599 133.455 133.981 1.00 48.62  ?  316 ALA A H    1 
ATOM   2629  H HA   . ALA A 1 316 ? 144.730 136.050 134.064 1.00 48.62  ?  316 ALA A HA   1 
ATOM   2630  H HB1  . ALA A 1 316 ? 147.051 135.758 134.073 1.00 48.62  ?  316 ALA A HB1  1 
ATOM   2631  H HB2  . ALA A 1 316 ? 146.856 134.233 133.674 1.00 48.62  ?  316 ALA A HB2  1 
ATOM   2632  H HB3  . ALA A 1 316 ? 146.360 134.752 135.091 1.00 48.62  ?  316 ALA A HB3  1 
ATOM   2633  N N    . ARG A 1 317 ? 145.018 134.926 131.131 1.00 46.84  ?  317 ARG A N    1 
ATOM   2634  C CA   . ARG A 1 317 ? 145.155 135.280 129.722 1.00 46.84  ?  317 ARG A CA   1 
ATOM   2635  C C    . ARG A 1 317 ? 143.816 135.242 128.993 1.00 46.84  ?  317 ARG A C    1 
ATOM   2636  O O    . ARG A 1 317 ? 143.782 135.034 127.776 1.00 46.84  ?  317 ARG A O    1 
ATOM   2637  C CB   . ARG A 1 317 ? 146.157 134.349 129.036 1.00 46.84  ?  317 ARG A CB   1 
ATOM   2638  C CG   . ARG A 1 317 ? 147.593 134.516 129.524 1.00 46.84  ?  317 ARG A CG   1 
ATOM   2639  C CD   . ARG A 1 317 ? 148.575 133.605 128.783 1.00 46.84  ?  317 ARG A CD   1 
ATOM   2640  N NE   . ARG A 1 317 ? 149.948 133.694 129.278 1.00 46.84  ?  317 ARG A NE   1 
ATOM   2641  C CZ   . ARG A 1 317 ? 150.956 132.923 128.877 1.00 46.84  ?  317 ARG A CZ   1 
ATOM   2642  N NH1  . ARG A 1 317 ? 152.162 133.090 129.399 1.00 46.84  1  317 ARG A NH1  1 
ATOM   2643  N NH2  . ARG A 1 317 ? 150.772 131.998 127.943 1.00 46.84  ?  317 ARG A NH2  1 
ATOM   2644  H H    . ARG A 1 317 ? 144.753 134.118 131.258 1.00 46.84  ?  317 ARG A H    1 
ATOM   2645  H HA   . ARG A 1 317 ? 145.500 136.183 129.656 1.00 46.84  ?  317 ARG A HA   1 
ATOM   2646  H HB2  . ARG A 1 317 ? 145.893 133.431 129.202 1.00 46.84  ?  317 ARG A HB2  1 
ATOM   2647  H HB3  . ARG A 1 317 ? 146.132 134.530 128.085 1.00 46.84  ?  317 ARG A HB3  1 
ATOM   2648  H HG2  . ARG A 1 317 ? 147.868 135.436 129.401 1.00 46.84  ?  317 ARG A HG2  1 
ATOM   2649  H HG3  . ARG A 1 317 ? 147.631 134.286 130.465 1.00 46.84  ?  317 ARG A HG3  1 
ATOM   2650  H HD2  . ARG A 1 317 ? 148.283 132.685 128.881 1.00 46.84  ?  317 ARG A HD2  1 
ATOM   2651  H HD3  . ARG A 1 317 ? 148.581 133.850 127.845 1.00 46.84  ?  317 ARG A HD3  1 
ATOM   2652  H HE   . ARG A 1 317 ? 150.117 134.289 129.877 1.00 46.84  ?  317 ARG A HE   1 
ATOM   2653  H HH11 . ARG A 1 317 ? 152.289 133.690 130.004 1.00 46.84  ?  317 ARG A HH11 1 
ATOM   2654  H HH12 . ARG A 1 317 ? 152.816 132.598 129.138 1.00 46.84  ?  317 ARG A HH12 1 
ATOM   2655  H HH21 . ARG A 1 317 ? 149.998 131.880 127.592 1.00 46.84  ?  317 ARG A HH21 1 
ATOM   2656  H HH22 . ARG A 1 317 ? 151.433 131.511 127.689 1.00 46.84  ?  317 ARG A HH22 1 
ATOM   2657  N N    . TYR A 1 318 ? 142.714 135.440 129.712 1.00 45.28  ?  318 TYR A N    1 
ATOM   2658  C CA   . TYR A 1 318 ? 141.375 135.413 129.140 1.00 45.28  ?  318 TYR A CA   1 
ATOM   2659  C C    . TYR A 1 318 ? 140.766 136.806 129.213 1.00 45.28  ?  318 TYR A C    1 
ATOM   2660  O O    . TYR A 1 318 ? 140.892 137.490 130.234 1.00 45.28  ?  318 TYR A O    1 
ATOM   2661  C CB   . TYR A 1 318 ? 140.487 134.406 129.875 1.00 45.28  ?  318 TYR A CB   1 
ATOM   2662  C CG   . TYR A 1 318 ? 139.029 134.471 129.481 1.00 45.28  ?  318 TYR A CG   1 
ATOM   2663  C CD1  . TYR A 1 318 ? 138.545 133.728 128.412 1.00 45.28  ?  318 TYR A CD1  1 
ATOM   2664  C CD2  . TYR A 1 318 ? 138.135 135.275 130.176 1.00 45.28  ?  318 TYR A CD2  1 
ATOM   2665  C CE1  . TYR A 1 318 ? 137.214 133.783 128.047 1.00 45.28  ?  318 TYR A CE1  1 
ATOM   2666  C CE2  . TYR A 1 318 ? 136.803 135.338 129.818 1.00 45.28  ?  318 TYR A CE2  1 
ATOM   2667  C CZ   . TYR A 1 318 ? 136.347 134.590 128.753 1.00 45.28  ?  318 TYR A CZ   1 
ATOM   2668  O OH   . TYR A 1 318 ? 135.021 134.649 128.394 1.00 45.28  ?  318 TYR A OH   1 
ATOM   2669  H H    . TYR A 1 318 ? 142.719 135.596 130.557 1.00 45.28  ?  318 TYR A H    1 
ATOM   2670  H HA   . TYR A 1 318 ? 141.425 135.150 128.207 1.00 45.28  ?  318 TYR A HA   1 
ATOM   2671  H HB2  . TYR A 1 318 ? 140.806 133.510 129.684 1.00 45.28  ?  318 TYR A HB2  1 
ATOM   2672  H HB3  . TYR A 1 318 ? 140.544 134.578 130.828 1.00 45.28  ?  318 TYR A HB3  1 
ATOM   2673  H HD1  . TYR A 1 318 ? 139.128 133.183 127.934 1.00 45.28  ?  318 TYR A HD1  1 
ATOM   2674  H HD2  . TYR A 1 318 ? 138.439 135.781 130.894 1.00 45.28  ?  318 TYR A HD2  1 
ATOM   2675  H HE1  . TYR A 1 318 ? 136.904 133.280 127.329 1.00 45.28  ?  318 TYR A HE1  1 
ATOM   2676  H HE2  . TYR A 1 318 ? 136.216 135.881 130.293 1.00 45.28  ?  318 TYR A HE2  1 
ATOM   2677  H HH   . TYR A 1 318 ? 134.890 134.192 127.702 1.00 45.28  ?  318 TYR A HH   1 
ATOM   2678  N N    . THR A 1 319 ? 140.108 137.218 128.131 1.00 48.72  ?  319 THR A N    1 
ATOM   2679  C CA   . THR A 1 319 ? 139.445 138.512 128.053 1.00 48.72  ?  319 THR A CA   1 
ATOM   2680  C C    . THR A 1 319 ? 137.982 138.304 127.692 1.00 48.72  ?  319 THR A C    1 
ATOM   2681  O O    . THR A 1 319 ? 137.636 137.346 126.994 1.00 48.72  ?  319 THR A O    1 
ATOM   2682  C CB   . THR A 1 319 ? 140.114 139.427 127.018 1.00 48.72  ?  319 THR A CB   1 
ATOM   2683  O OG1  . THR A 1 319 ? 139.542 140.739 127.094 1.00 48.72  ?  319 THR A OG1  1 
ATOM   2684  C CG2  . THR A 1 319 ? 139.931 138.875 125.610 1.00 48.72  ?  319 THR A CG2  1 
ATOM   2685  H H    . THR A 1 319 ? 140.031 136.752 127.413 1.00 48.72  ?  319 THR A H    1 
ATOM   2686  H HA   . THR A 1 319 ? 139.485 138.950 128.918 1.00 48.72  ?  319 THR A HA   1 
ATOM   2687  H HB   . THR A 1 319 ? 141.065 139.481 127.203 1.00 48.72  ?  319 THR A HB   1 
ATOM   2688  H HG1  . THR A 1 319 ? 139.917 141.249 126.541 1.00 48.72  ?  319 THR A HG1  1 
ATOM   2689  H HG21 . THR A 1 319 ? 140.091 137.919 125.606 1.00 48.72  ?  319 THR A HG21 1 
ATOM   2690  H HG22 . THR A 1 319 ? 140.557 139.302 125.004 1.00 48.72  ?  319 THR A HG22 1 
ATOM   2691  H HG23 . THR A 1 319 ? 139.027 139.044 125.300 1.00 48.72  ?  319 THR A HG23 1 
ATOM   2692  N N    . THR A 1 320 ? 137.130 139.203 128.170 1.00 49.53  ?  320 THR A N    1 
ATOM   2693  C CA   . THR A 1 320 ? 135.701 139.076 127.925 1.00 49.53  ?  320 THR A CA   1 
ATOM   2694  C C    . THR A 1 320 ? 135.425 139.152 126.425 1.00 49.53  ?  320 THR A C    1 
ATOM   2695  O O    . THR A 1 320 ? 135.950 140.048 125.749 1.00 49.53  ?  320 THR A O    1 
ATOM   2696  C CB   . THR A 1 320 ? 134.932 140.176 128.655 1.00 49.53  ?  320 THR A CB   1 
ATOM   2697  O OG1  . THR A 1 320 ? 135.362 140.239 130.021 1.00 49.53  ?  320 THR A OG1  1 
ATOM   2698  C CG2  . THR A 1 320 ? 133.435 139.903 128.611 1.00 49.53  ?  320 THR A CG2  1 
ATOM   2699  H H    . THR A 1 320 ? 137.352 139.890 128.637 1.00 49.53  ?  320 THR A H    1 
ATOM   2700  H HA   . THR A 1 320 ? 135.403 138.220 128.266 1.00 49.53  ?  320 THR A HA   1 
ATOM   2701  H HB   . THR A 1 320 ? 135.101 141.028 128.224 1.00 49.53  ?  320 THR A HB   1 
ATOM   2702  H HG1  . THR A 1 320 ? 134.942 140.843 130.426 1.00 49.53  ?  320 THR A HG1  1 
ATOM   2703  H HG21 . THR A 1 320 ? 132.960 140.578 129.121 1.00 49.53  ?  320 THR A HG21 1 
ATOM   2704  H HG22 . THR A 1 320 ? 133.247 139.031 128.992 1.00 49.53  ?  320 THR A HG22 1 
ATOM   2705  H HG23 . THR A 1 320 ? 133.120 139.921 127.694 1.00 49.53  ?  320 THR A HG23 1 
ATOM   2706  N N    . PRO A 1 321 ? 134.618 138.248 125.868 1.00 52.20  ?  321 PRO A N    1 
ATOM   2707  C CA   . PRO A 1 321 ? 134.326 138.320 124.431 1.00 52.20  ?  321 PRO A CA   1 
ATOM   2708  C C    . PRO A 1 321 ? 133.585 139.600 124.078 1.00 52.20  ?  321 PRO A C    1 
ATOM   2709  O O    . PRO A 1 321 ? 132.799 140.125 124.870 1.00 52.20  ?  321 PRO A O    1 
ATOM   2710  C CB   . PRO A 1 321 ? 133.464 137.077 124.178 1.00 52.20  ?  321 PRO A CB   1 
ATOM   2711  C CG   . PRO A 1 321 ? 132.894 136.726 125.506 1.00 52.20  ?  321 PRO A CG   1 
ATOM   2712  C CD   . PRO A 1 321 ? 133.927 137.118 126.513 1.00 52.20  ?  321 PRO A CD   1 
ATOM   2713  H HA   . PRO A 1 321 ? 135.144 138.261 123.912 1.00 52.20  ?  321 PRO A HA   1 
ATOM   2714  H HB2  . PRO A 1 321 ? 132.758 137.291 123.548 1.00 52.20  ?  321 PRO A HB2  1 
ATOM   2715  H HB3  . PRO A 1 321 ? 134.019 136.357 123.841 1.00 52.20  ?  321 PRO A HB3  1 
ATOM   2716  H HG2  . PRO A 1 321 ? 132.073 137.222 125.649 1.00 52.20  ?  321 PRO A HG2  1 
ATOM   2717  H HG3  . PRO A 1 321 ? 132.726 135.771 125.545 1.00 52.20  ?  321 PRO A HG3  1 
ATOM   2718  H HD2  . PRO A 1 321 ? 133.502 137.405 127.336 1.00 52.20  ?  321 PRO A HD2  1 
ATOM   2719  H HD3  . PRO A 1 321 ? 134.545 136.387 126.667 1.00 52.20  ?  321 PRO A HD3  1 
ATOM   2720  N N    . GLU A 1 322 ? 133.845 140.103 122.869 1.00 60.95  ?  322 GLU A N    1 
ATOM   2721  C CA   . GLU A 1 322 ? 133.192 141.325 122.414 1.00 60.95  ?  322 GLU A CA   1 
ATOM   2722  C C    . GLU A 1 322 ? 131.685 141.157 122.269 1.00 60.95  ?  322 GLU A C    1 
ATOM   2723  O O    . GLU A 1 322 ? 130.947 142.133 122.443 1.00 60.95  ?  322 GLU A O    1 
ATOM   2724  C CB   . GLU A 1 322 ? 133.798 141.782 121.085 1.00 60.95  ?  322 GLU A CB   1 
ATOM   2725  C CG   . GLU A 1 322 ? 133.674 140.777 119.945 1.00 60.95  ?  322 GLU A CG   1 
ATOM   2726  C CD   . GLU A 1 322 ? 134.892 139.883 119.820 1.00 60.95  ?  322 GLU A CD   1 
ATOM   2727  O OE1  . GLU A 1 322 ? 135.498 139.551 120.861 1.00 60.95  ?  322 GLU A OE1  1 
ATOM   2728  O OE2  . GLU A 1 322 ? 135.245 139.512 118.680 1.00 60.95  -1 322 GLU A OE2  1 
ATOM   2729  H H    . GLU A 1 322 ? 134.390 139.757 122.302 1.00 60.95  ?  322 GLU A H    1 
ATOM   2730  H HA   . GLU A 1 322 ? 133.350 142.024 123.068 1.00 60.95  ?  322 GLU A HA   1 
ATOM   2731  H HB2  . GLU A 1 322 ? 133.352 142.598 120.806 1.00 60.95  ?  322 GLU A HB2  1 
ATOM   2732  H HB3  . GLU A 1 322 ? 134.743 141.957 121.220 1.00 60.95  ?  322 GLU A HB3  1 
ATOM   2733  H HG2  . GLU A 1 322 ? 132.903 140.210 120.094 1.00 60.95  ?  322 GLU A HG2  1 
ATOM   2734  H HG3  . GLU A 1 322 ? 133.572 141.260 119.110 1.00 60.95  ?  322 GLU A HG3  1 
ATOM   2735  N N    . ASP A 1 323 ? 131.214 139.955 121.958 1.00 57.61  ?  323 ASP A N    1 
ATOM   2736  C CA   . ASP A 1 323 ? 129.785 139.686 121.790 1.00 57.61  ?  323 ASP A CA   1 
ATOM   2737  C C    . ASP A 1 323 ? 129.146 139.267 123.109 1.00 57.61  ?  323 ASP A C    1 
ATOM   2738  O O    . ASP A 1 323 ? 128.559 138.191 123.226 1.00 57.61  ?  323 ASP A O    1 
ATOM   2739  C CB   . ASP A 1 323 ? 129.578 138.621 120.719 1.00 57.61  ?  323 ASP A CB   1 
ATOM   2740  C CG   . ASP A 1 323 ? 128.194 138.676 120.099 1.00 57.61  ?  323 ASP A CG   1 
ATOM   2741  O OD1  . ASP A 1 323 ? 127.396 139.554 120.491 1.00 57.61  ?  323 ASP A OD1  1 
ATOM   2742  O OD2  . ASP A 1 323 ? 127.904 137.840 119.218 1.00 57.61  -1 323 ASP A OD2  1 
ATOM   2743  H H    . ASP A 1 323 ? 131.710 139.264 121.836 1.00 57.61  ?  323 ASP A H    1 
ATOM   2744  H HA   . ASP A 1 323 ? 129.348 140.499 121.493 1.00 57.61  ?  323 ASP A HA   1 
ATOM   2745  H HB2  . ASP A 1 323 ? 130.227 138.756 120.012 1.00 57.61  ?  323 ASP A HB2  1 
ATOM   2746  H HB3  . ASP A 1 323 ? 129.696 137.744 121.115 1.00 57.61  ?  323 ASP A HB3  1 
ATOM   2747  N N    . ALA A 1 324 ? 129.257 140.125 124.120 1.00 55.55  ?  324 ALA A N    1 
ATOM   2748  C CA   . ALA A 1 324 ? 128.708 139.866 125.443 1.00 55.55  ?  324 ALA A CA   1 
ATOM   2749  C C    . ALA A 1 324 ? 127.840 141.039 125.870 1.00 55.55  ?  324 ALA A C    1 
ATOM   2750  O O    . ALA A 1 324 ? 128.210 142.200 125.673 1.00 55.55  ?  324 ALA A O    1 
ATOM   2751  C CB   . ALA A 1 324 ? 129.820 139.637 126.472 1.00 55.55  ?  324 ALA A CB   1 
ATOM   2752  H H    . ALA A 1 324 ? 129.658 140.883 124.061 1.00 55.55  ?  324 ALA A H    1 
ATOM   2753  H HA   . ALA A 1 324 ? 128.152 139.072 125.414 1.00 55.55  ?  324 ALA A HA   1 
ATOM   2754  H HB1  . ALA A 1 324 ? 129.421 139.537 127.350 1.00 55.55  ?  324 ALA A HB1  1 
ATOM   2755  H HB2  . ALA A 1 324 ? 130.310 138.833 126.236 1.00 55.55  ?  324 ALA A HB2  1 
ATOM   2756  H HB3  . ALA A 1 324 ? 130.416 140.402 126.468 1.00 55.55  ?  324 ALA A HB3  1 
ATOM   2757  N N    . THR A 1 325 ? 126.679 140.727 126.461 1.00 60.05  ?  325 THR A N    1 
ATOM   2758  C CA   . THR A 1 325 ? 125.754 141.754 126.928 1.00 60.05  ?  325 THR A CA   1 
ATOM   2759  C C    . THR A 1 325 ? 125.716 141.764 128.446 1.00 60.05  ?  325 THR A C    1 
ATOM   2760  O O    . THR A 1 325 ? 125.070 140.892 129.046 1.00 60.05  ?  325 THR A O    1 
ATOM   2761  C CB   . THR A 1 325 ? 124.352 141.500 126.382 1.00 60.05  ?  325 THR A CB   1 
ATOM   2762  O OG1  . THR A 1 325 ? 123.942 140.165 126.706 1.00 60.05  ?  325 THR A OG1  1 
ATOM   2763  C CG2  . THR A 1 325 ? 124.323 141.685 124.872 1.00 60.05  ?  325 THR A CG2  1 
ATOM   2764  H H    . THR A 1 325 ? 126.408 139.923 126.602 1.00 60.05  ?  325 THR A H    1 
ATOM   2765  H HA   . THR A 1 325 ? 126.043 142.622 126.610 1.00 60.05  ?  325 THR A HA   1 
ATOM   2766  H HB   . THR A 1 325 ? 123.733 142.132 126.781 1.00 60.05  ?  325 THR A HB   1 
ATOM   2767  H HG1  . THR A 1 325 ? 123.921 140.065 127.540 1.00 60.05  ?  325 THR A HG1  1 
ATOM   2768  H HG21 . THR A 1 325 ? 123.423 141.544 124.539 1.00 60.05  ?  325 THR A HG21 1 
ATOM   2769  H HG22 . THR A 1 325 ? 124.608 142.583 124.642 1.00 60.05  ?  325 THR A HG22 1 
ATOM   2770  H HG23 . THR A 1 325 ? 124.920 141.047 124.450 1.00 60.05  ?  325 THR A HG23 1 
ATOM   2771  N N    . PRO A 1 326 ? 126.376 142.711 129.107 1.00 62.18  ?  326 PRO A N    1 
ATOM   2772  C CA   . PRO A 1 326 ? 126.328 142.755 130.569 1.00 62.18  ?  326 PRO A CA   1 
ATOM   2773  C C    . PRO A 1 326 ? 125.129 143.535 131.082 1.00 62.18  ?  326 PRO A C    1 
ATOM   2774  O O    . PRO A 1 326 ? 124.665 144.497 130.466 1.00 62.18  ?  326 PRO A O    1 
ATOM   2775  C CB   . PRO A 1 326 ? 127.639 143.458 130.935 1.00 62.18  ?  326 PRO A CB   1 
ATOM   2776  C CG   . PRO A 1 326 ? 127.860 144.399 129.800 1.00 62.18  ?  326 PRO A CG   1 
ATOM   2777  C CD   . PRO A 1 326 ? 127.312 143.712 128.564 1.00 62.18  ?  326 PRO A CD   1 
ATOM   2778  H HA   . PRO A 1 326 ? 126.321 141.859 130.942 1.00 62.18  ?  326 PRO A HA   1 
ATOM   2779  H HB2  . PRO A 1 326 ? 127.536 143.939 131.771 1.00 62.18  ?  326 PRO A HB2  1 
ATOM   2780  H HB3  . PRO A 1 326 ? 128.356 142.808 130.991 1.00 62.18  ?  326 PRO A HB3  1 
ATOM   2781  H HG2  . PRO A 1 326 ? 127.383 145.227 129.968 1.00 62.18  ?  326 PRO A HG2  1 
ATOM   2782  H HG3  . PRO A 1 326 ? 128.810 144.568 129.702 1.00 62.18  ?  326 PRO A HG3  1 
ATOM   2783  H HD2  . PRO A 1 326 ? 126.840 144.350 128.006 1.00 62.18  ?  326 PRO A HD2  1 
ATOM   2784  H HD3  . PRO A 1 326 ? 128.027 143.275 128.076 1.00 62.18  ?  326 PRO A HD3  1 
ATOM   2785  N N    . GLU A 1 327 ? 124.631 143.101 132.232 1.00 65.36  ?  327 GLU A N    1 
ATOM   2786  C CA   . GLU A 1 327 ? 123.548 143.822 132.889 1.00 65.36  ?  327 GLU A CA   1 
ATOM   2787  C C    . GLU A 1 327 ? 124.060 145.191 133.325 1.00 65.36  ?  327 GLU A C    1 
ATOM   2788  O O    . GLU A 1 327 ? 125.171 145.285 133.860 1.00 65.36  ?  327 GLU A O    1 
ATOM   2789  C CB   . GLU A 1 327 ? 123.041 143.039 134.097 1.00 65.36  ?  327 GLU A CB   1 
ATOM   2790  C CG   . GLU A 1 327 ? 121.760 143.585 134.714 1.00 65.36  ?  327 GLU A CG   1 
ATOM   2791  C CD   . GLU A 1 327 ? 122.004 144.729 135.684 1.00 65.36  ?  327 GLU A CD   1 
ATOM   2792  O OE1  . GLU A 1 327 ? 123.087 144.777 136.305 1.00 65.36  ?  327 GLU A OE1  1 
ATOM   2793  O OE2  . GLU A 1 327 ? 121.106 145.586 135.819 1.00 65.36  -1 327 GLU A OE2  1 
ATOM   2794  H H    . GLU A 1 327 ? 124.901 142.401 132.651 1.00 65.36  ?  327 GLU A H    1 
ATOM   2795  H HA   . GLU A 1 327 ? 122.815 143.930 132.265 1.00 65.36  ?  327 GLU A HA   1 
ATOM   2796  H HB2  . GLU A 1 327 ? 122.874 142.124 133.822 1.00 65.36  ?  327 GLU A HB2  1 
ATOM   2797  H HB3  . GLU A 1 327 ? 123.724 143.061 134.782 1.00 65.36  ?  327 GLU A HB3  1 
ATOM   2798  H HG2  . GLU A 1 327 ? 121.177 143.897 134.008 1.00 65.36  ?  327 GLU A HG2  1 
ATOM   2799  H HG3  . GLU A 1 327 ? 121.324 142.876 135.212 1.00 65.36  ?  327 GLU A HG3  1 
ATOM   2800  N N    . PRO A 1 328 ? 123.297 146.272 133.116 1.00 66.87  ?  328 PRO A N    1 
ATOM   2801  C CA   . PRO A 1 328 ? 123.794 147.596 133.518 1.00 66.87  ?  328 PRO A CA   1 
ATOM   2802  C C    . PRO A 1 328 ? 124.138 147.666 134.997 1.00 66.87  ?  328 PRO A C    1 
ATOM   2803  O O    . PRO A 1 328 ? 123.258 147.557 135.857 1.00 66.87  ?  328 PRO A O    1 
ATOM   2804  C CB   . PRO A 1 328 ? 122.633 148.536 133.157 1.00 66.87  ?  328 PRO A CB   1 
ATOM   2805  C CG   . PRO A 1 328 ? 121.435 147.657 133.027 1.00 66.87  ?  328 PRO A CG   1 
ATOM   2806  C CD   . PRO A 1 328 ? 121.955 146.354 132.515 1.00 66.87  ?  328 PRO A CD   1 
ATOM   2807  H HA   . PRO A 1 328 ? 124.574 147.838 132.996 1.00 66.87  ?  328 PRO A HA   1 
ATOM   2808  H HB2  . PRO A 1 328 ? 122.504 149.188 133.864 1.00 66.87  ?  328 PRO A HB2  1 
ATOM   2809  H HB3  . PRO A 1 328 ? 122.823 148.978 132.315 1.00 66.87  ?  328 PRO A HB3  1 
ATOM   2810  H HG2  . PRO A 1 328 ? 121.013 147.544 133.894 1.00 66.87  ?  328 PRO A HG2  1 
ATOM   2811  H HG3  . PRO A 1 328 ? 120.814 148.048 132.393 1.00 66.87  ?  328 PRO A HG3  1 
ATOM   2812  H HD2  . PRO A 1 328 ? 121.393 145.628 132.821 1.00 66.87  ?  328 PRO A HD2  1 
ATOM   2813  H HD3  . PRO A 1 328 ? 122.017 146.371 131.547 1.00 66.87  ?  328 PRO A HD3  1 
ATOM   2814  N N    . GLY A 1 329 ? 125.421 147.850 135.299 1.00 65.44  ?  329 GLY A N    1 
ATOM   2815  C CA   . GLY A 1 329 ? 125.895 148.008 136.663 1.00 65.44  ?  329 GLY A CA   1 
ATOM   2816  C C    . GLY A 1 329 ? 126.937 147.004 137.111 1.00 65.44  ?  329 GLY A C    1 
ATOM   2817  O O    . GLY A 1 329 ? 127.580 147.236 138.146 1.00 65.44  ?  329 GLY A O    1 
ATOM   2818  H H    . GLY A 1 329 ? 126.048 147.885 134.711 1.00 65.44  ?  329 GLY A H    1 
ATOM   2819  H HA2  . GLY A 1 329 ? 126.283 148.893 136.755 1.00 65.44  ?  329 GLY A HA2  1 
ATOM   2820  H HA3  . GLY A 1 329 ? 125.144 147.947 137.273 1.00 65.44  ?  329 GLY A HA3  1 
ATOM   2821  N N    . GLU A 1 330 ? 127.150 145.898 136.400 1.00 61.91  ?  330 GLU A N    1 
ATOM   2822  C CA   . GLU A 1 330 ? 128.166 144.940 136.819 1.00 61.91  ?  330 GLU A CA   1 
ATOM   2823  C C    . GLU A 1 330 ? 129.558 145.451 136.468 1.00 61.91  ?  330 GLU A C    1 
ATOM   2824  O O    . GLU A 1 330 ? 129.777 146.009 135.388 1.00 61.91  ?  330 GLU A O    1 
ATOM   2825  C CB   . GLU A 1 330 ? 127.935 143.572 136.175 1.00 61.91  ?  330 GLU A CB   1 
ATOM   2826  C CG   . GLU A 1 330 ? 126.508 143.050 136.259 1.00 61.91  ?  330 GLU A CG   1 
ATOM   2827  C CD   . GLU A 1 330 ? 126.314 141.762 135.474 1.00 61.91  ?  330 GLU A CD   1 
ATOM   2828  O OE1  . GLU A 1 330 ? 127.327 141.147 135.079 1.00 61.91  ?  330 GLU A OE1  1 
ATOM   2829  O OE2  . GLU A 1 330 ? 125.154 141.355 135.259 1.00 61.91  -1 330 GLU A OE2  1 
ATOM   2830  H H    . GLU A 1 330 ? 126.727 145.686 135.682 1.00 61.91  ?  330 GLU A H    1 
ATOM   2831  H HA   . GLU A 1 330 ? 128.119 144.829 137.781 1.00 61.91  ?  330 GLU A HA   1 
ATOM   2832  H HB2  . GLU A 1 330 ? 128.172 143.634 135.236 1.00 61.91  ?  330 GLU A HB2  1 
ATOM   2833  H HB3  . GLU A 1 330 ? 128.508 142.924 136.615 1.00 61.91  ?  330 GLU A HB3  1 
ATOM   2834  H HG2  . GLU A 1 330 ? 126.288 142.874 137.187 1.00 61.91  ?  330 GLU A HG2  1 
ATOM   2835  H HG3  . GLU A 1 330 ? 125.905 143.717 135.895 1.00 61.91  ?  330 GLU A HG3  1 
ATOM   2836  N N    . ASP A 1 331 ? 130.497 145.259 137.388 1.00 57.40  ?  331 ASP A N    1 
ATOM   2837  C CA   . ASP A 1 331 ? 131.879 145.627 137.128 1.00 57.40  ?  331 ASP A CA   1 
ATOM   2838  C C    . ASP A 1 331 ? 132.455 144.733 136.030 1.00 57.40  ?  331 ASP A C    1 
ATOM   2839  O O    . ASP A 1 331 ? 132.062 143.569 135.910 1.00 57.40  ?  331 ASP A O    1 
ATOM   2840  C CB   . ASP A 1 331 ? 132.704 145.500 138.411 1.00 57.40  ?  331 ASP A CB   1 
ATOM   2841  C CG   . ASP A 1 331 ? 134.161 145.863 138.213 1.00 57.40  ?  331 ASP A CG   1 
ATOM   2842  O OD1  . ASP A 1 331 ? 134.878 145.107 137.525 1.00 57.40  ?  331 ASP A OD1  1 
ATOM   2843  O OD2  . ASP A 1 331 ? 134.593 146.907 138.747 1.00 57.40  -1 331 ASP A OD2  1 
ATOM   2844  H H    . ASP A 1 331 ? 130.360 144.919 138.166 1.00 57.40  ?  331 ASP A H    1 
ATOM   2845  H HA   . ASP A 1 331 ? 131.906 146.551 136.837 1.00 57.40  ?  331 ASP A HA   1 
ATOM   2846  H HB2  . ASP A 1 331 ? 132.335 146.098 139.080 1.00 57.40  ?  331 ASP A HB2  1 
ATOM   2847  H HB3  . ASP A 1 331 ? 132.660 144.584 138.726 1.00 57.40  ?  331 ASP A HB3  1 
ATOM   2848  N N    . PRO A 1 332 ? 133.378 145.245 135.208 1.00 56.38  ?  332 PRO A N    1 
ATOM   2849  C CA   . PRO A 1 332 ? 133.927 144.403 134.130 1.00 56.38  ?  332 PRO A CA   1 
ATOM   2850  C C    . PRO A 1 332 ? 134.549 143.107 134.623 1.00 56.38  ?  332 PRO A C    1 
ATOM   2851  O O    . PRO A 1 332 ? 134.497 142.096 133.913 1.00 56.38  ?  332 PRO A O    1 
ATOM   2852  C CB   . PRO A 1 332 ? 134.966 145.322 133.473 1.00 56.38  ?  332 PRO A CB   1 
ATOM   2853  C CG   . PRO A 1 332 ? 134.470 146.695 133.741 1.00 56.38  ?  332 PRO A CG   1 
ATOM   2854  C CD   . PRO A 1 332 ? 133.856 146.637 135.108 1.00 56.38  ?  332 PRO A CD   1 
ATOM   2855  H HA   . PRO A 1 332 ? 133.234 144.196 133.483 1.00 56.38  ?  332 PRO A HA   1 
ATOM   2856  H HB2  . PRO A 1 332 ? 135.835 145.184 133.883 1.00 56.38  ?  332 PRO A HB2  1 
ATOM   2857  H HB3  . PRO A 1 332 ? 135.002 145.149 132.519 1.00 56.38  ?  332 PRO A HB3  1 
ATOM   2858  H HG2  . PRO A 1 332 ? 135.213 147.319 133.725 1.00 56.38  ?  332 PRO A HG2  1 
ATOM   2859  H HG3  . PRO A 1 332 ? 133.806 146.937 133.077 1.00 56.38  ?  332 PRO A HG3  1 
ATOM   2860  H HD2  . PRO A 1 332 ? 134.529 146.818 135.781 1.00 56.38  ?  332 PRO A HD2  1 
ATOM   2861  H HD3  . PRO A 1 332 ? 133.115 147.259 135.168 1.00 56.38  ?  332 PRO A HD3  1 
ATOM   2862  N N    . ARG A 1 333 ? 135.147 143.106 135.817 1.00 54.49  ?  333 ARG A N    1 
ATOM   2863  C CA   . ARG A 1 333 ? 135.750 141.883 136.338 1.00 54.49  ?  333 ARG A CA   1 
ATOM   2864  C C    . ARG A 1 333 ? 134.700 140.805 136.585 1.00 54.49  ?  333 ARG A C    1 
ATOM   2865  O O    . ARG A 1 333 ? 134.938 139.623 136.309 1.00 54.49  ?  333 ARG A O    1 
ATOM   2866  C CB   . ARG A 1 333 ? 136.521 142.187 137.623 1.00 54.49  ?  333 ARG A CB   1 
ATOM   2867  C CG   . ARG A 1 333 ? 137.642 143.198 137.445 1.00 54.49  ?  333 ARG A CG   1 
ATOM   2868  C CD   . ARG A 1 333 ? 138.143 143.723 138.780 1.00 54.49  ?  333 ARG A CD   1 
ATOM   2869  N NE   . ARG A 1 333 ? 137.158 144.578 139.439 1.00 54.49  ?  333 ARG A NE   1 
ATOM   2870  C CZ   . ARG A 1 333 ? 137.117 144.811 140.748 1.00 54.49  ?  333 ARG A CZ   1 
ATOM   2871  N NH1  . ARG A 1 333 ? 136.180 145.604 141.249 1.00 54.49  1  333 ARG A NH1  1 
ATOM   2872  N NH2  . ARG A 1 333 ? 138.011 144.259 141.558 1.00 54.49  ?  333 ARG A NH2  1 
ATOM   2873  H H    . ARG A 1 333 ? 135.214 143.789 136.335 1.00 54.49  ?  333 ARG A H    1 
ATOM   2874  H HA   . ARG A 1 333 ? 136.381 141.541 135.686 1.00 54.49  ?  333 ARG A HA   1 
ATOM   2875  H HB2  . ARG A 1 333 ? 135.903 142.542 138.281 1.00 54.49  ?  333 ARG A HB2  1 
ATOM   2876  H HB3  . ARG A 1 333 ? 136.914 141.363 137.953 1.00 54.49  ?  333 ARG A HB3  1 
ATOM   2877  H HG2  . ARG A 1 333 ? 138.386 142.773 136.989 1.00 54.49  ?  333 ARG A HG2  1 
ATOM   2878  H HG3  . ARG A 1 333 ? 137.318 143.951 136.927 1.00 54.49  ?  333 ARG A HG3  1 
ATOM   2879  H HD2  . ARG A 1 333 ? 138.330 142.969 139.361 1.00 54.49  ?  333 ARG A HD2  1 
ATOM   2880  H HD3  . ARG A 1 333 ? 138.948 144.244 138.637 1.00 54.49  ?  333 ARG A HD3  1 
ATOM   2881  H HE   . ARG A 1 333 ? 136.575 144.971 138.944 1.00 54.49  ?  333 ARG A HE   1 
ATOM   2882  H HH11 . ARG A 1 333 ? 135.598 145.965 140.728 1.00 54.49  ?  333 ARG A HH11 1 
ATOM   2883  H HH12 . ARG A 1 333 ? 136.153 145.757 142.094 1.00 54.49  ?  333 ARG A HH12 1 
ATOM   2884  H HH21 . ARG A 1 333 ? 138.623 143.744 141.244 1.00 54.49  ?  333 ARG A HH21 1 
ATOM   2885  H HH22 . ARG A 1 333 ? 137.977 144.417 142.403 1.00 54.49  ?  333 ARG A HH22 1 
ATOM   2886  N N    . VAL A 1 334 ? 133.536 141.190 137.114 1.00 53.17  ?  334 VAL A N    1 
ATOM   2887  C CA   . VAL A 1 334 ? 132.477 140.215 137.354 1.00 53.17  ?  334 VAL A CA   1 
ATOM   2888  C C    . VAL A 1 334 ? 132.018 139.595 136.041 1.00 53.17  ?  334 VAL A C    1 
ATOM   2889  O O    . VAL A 1 334 ? 131.843 138.374 135.942 1.00 53.17  ?  334 VAL A O    1 
ATOM   2890  C CB   . VAL A 1 334 ? 131.304 140.869 138.107 1.00 53.17  ?  334 VAL A CB   1 
ATOM   2891  C CG1  . VAL A 1 334 ? 130.276 139.819 138.501 1.00 53.17  ?  334 VAL A CG1  1 
ATOM   2892  C CG2  . VAL A 1 334 ? 131.802 141.614 139.338 1.00 53.17  ?  334 VAL A CG2  1 
ATOM   2893  H H    . VAL A 1 334 ? 133.340 141.998 137.333 1.00 53.17  ?  334 VAL A H    1 
ATOM   2894  H HA   . VAL A 1 334 ? 132.827 139.503 137.912 1.00 53.17  ?  334 VAL A HA   1 
ATOM   2895  H HB   . VAL A 1 334 ? 130.870 141.510 137.522 1.00 53.17  ?  334 VAL A HB   1 
ATOM   2896  H HG11 . VAL A 1 334 ? 129.604 140.232 139.066 1.00 53.17  ?  334 VAL A HG11 1 
ATOM   2897  H HG12 . VAL A 1 334 ? 129.861 139.465 137.699 1.00 53.17  ?  334 VAL A HG12 1 
ATOM   2898  H HG13 . VAL A 1 334 ? 130.723 139.107 138.986 1.00 53.17  ?  334 VAL A HG13 1 
ATOM   2899  H HG21 . VAL A 1 334 ? 131.039 141.884 139.873 1.00 53.17  ?  334 VAL A HG21 1 
ATOM   2900  H HG22 . VAL A 1 334 ? 132.375 141.025 139.853 1.00 53.17  ?  334 VAL A HG22 1 
ATOM   2901  H HG23 . VAL A 1 334 ? 132.301 142.397 139.057 1.00 53.17  ?  334 VAL A HG23 1 
ATOM   2902  N N    . THR A 1 335 ? 131.811 140.424 135.016 1.00 51.44  ?  335 THR A N    1 
ATOM   2903  C CA   . THR A 1 335 ? 131.406 139.902 133.715 1.00 51.44  ?  335 THR A CA   1 
ATOM   2904  C C    . THR A 1 335 ? 132.483 138.996 133.134 1.00 51.44  ?  335 THR A C    1 
ATOM   2905  O O    . THR A 1 335 ? 132.179 137.953 132.542 1.00 51.44  ?  335 THR A O    1 
ATOM   2906  C CB   . THR A 1 335 ? 131.103 141.052 132.754 1.00 51.44  ?  335 THR A CB   1 
ATOM   2907  O OG1  . THR A 1 335 ? 132.325 141.701 132.379 1.00 51.44  ?  335 THR A OG1  1 
ATOM   2908  C CG2  . THR A 1 335 ? 130.167 142.067 133.400 1.00 51.44  ?  335 THR A CG2  1 
ATOM   2909  H H    . THR A 1 335 ? 131.905 141.278 135.049 1.00 51.44  ?  335 THR A H    1 
ATOM   2910  H HA   . THR A 1 335 ? 130.597 139.378 133.822 1.00 51.44  ?  335 THR A HA   1 
ATOM   2911  H HB   . THR A 1 335 ? 130.670 140.702 131.960 1.00 51.44  ?  335 THR A HB   1 
ATOM   2912  H HG1  . THR A 1 335 ? 132.725 141.979 133.063 1.00 51.44  ?  335 THR A HG1  1 
ATOM   2913  H HG21 . THR A 1 335 ? 129.832 142.681 132.728 1.00 51.44  ?  335 THR A HG21 1 
ATOM   2914  H HG22 . THR A 1 335 ? 130.639 142.574 134.078 1.00 51.44  ?  335 THR A HG22 1 
ATOM   2915  H HG23 . THR A 1 335 ? 129.416 141.610 133.810 1.00 51.44  ?  335 THR A HG23 1 
ATOM   2916  N N    . ARG A 1 336 ? 133.751 139.382 133.292 1.00 47.57  ?  336 ARG A N    1 
ATOM   2917  C CA   . ARG A 1 336 ? 134.842 138.557 132.789 1.00 47.57  ?  336 ARG A CA   1 
ATOM   2918  C C    . ARG A 1 336 ? 134.844 137.189 133.454 1.00 47.57  ?  336 ARG A C    1 
ATOM   2919  O O    . ARG A 1 336 ? 134.977 136.165 132.777 1.00 47.57  ?  336 ARG A O    1 
ATOM   2920  C CB   . ARG A 1 336 ? 136.179 139.265 133.013 1.00 47.57  ?  336 ARG A CB   1 
ATOM   2921  C CG   . ARG A 1 336 ? 137.388 138.481 132.523 1.00 47.57  ?  336 ARG A CG   1 
ATOM   2922  C CD   . ARG A 1 336 ? 138.646 139.335 132.545 1.00 47.57  ?  336 ARG A CD   1 
ATOM   2923  N NE   . ARG A 1 336 ? 139.862 138.521 132.602 1.00 47.57  ?  336 ARG A NE   1 
ATOM   2924  C CZ   . ARG A 1 336 ? 140.830 138.650 133.507 1.00 47.57  ?  336 ARG A CZ   1 
ATOM   2925  N NH1  . ARG A 1 336 ? 141.886 137.850 133.454 1.00 47.57  1  336 ARG A NH1  1 
ATOM   2926  N NH2  . ARG A 1 336 ? 140.761 139.569 134.463 1.00 47.57  ?  336 ARG A NH2  1 
ATOM   2927  H H    . ARG A 1 336 ? 134.001 140.107 133.682 1.00 47.57  ?  336 ARG A H    1 
ATOM   2928  H HA   . ARG A 1 336 ? 134.727 138.427 131.835 1.00 47.57  ?  336 ARG A HA   1 
ATOM   2929  H HB2  . ARG A 1 336 ? 136.166 140.112 132.542 1.00 47.57  ?  336 ARG A HB2  1 
ATOM   2930  H HB3  . ARG A 1 336 ? 136.294 139.420 133.964 1.00 47.57  ?  336 ARG A HB3  1 
ATOM   2931  H HG2  . ARG A 1 336 ? 137.531 137.716 133.102 1.00 47.57  ?  336 ARG A HG2  1 
ATOM   2932  H HG3  . ARG A 1 336 ? 137.233 138.189 131.612 1.00 47.57  ?  336 ARG A HG3  1 
ATOM   2933  H HD2  . ARG A 1 336 ? 138.680 139.863 131.732 1.00 47.57  ?  336 ARG A HD2  1 
ATOM   2934  H HD3  . ARG A 1 336 ? 138.609 139.918 133.316 1.00 47.57  ?  336 ARG A HD3  1 
ATOM   2935  H HE   . ARG A 1 336 ? 139.959 137.912 132.002 1.00 47.57  ?  336 ARG A HE   1 
ATOM   2936  H HH11 . ARG A 1 336 ? 141.943 137.251 132.839 1.00 47.57  ?  336 ARG A HH11 1 
ATOM   2937  H HH12 . ARG A 1 336 ? 142.515 137.929 134.035 1.00 47.57  ?  336 ARG A HH12 1 
ATOM   2938  H HH21 . ARG A 1 336 ? 140.087 140.098 134.516 1.00 47.57  ?  336 ARG A HH21 1 
ATOM   2939  H HH22 . ARG A 1 336 ? 141.398 139.635 135.036 1.00 47.57  ?  336 ARG A HH22 1 
ATOM   2940  N N    . ALA A 1 337 ? 134.690 137.149 134.779 1.00 46.50  ?  337 ALA A N    1 
ATOM   2941  C CA   . ALA A 1 337 ? 134.671 135.868 135.482 1.00 46.50  ?  337 ALA A CA   1 
ATOM   2942  C C    . ALA A 1 337 ? 133.466 135.032 135.065 1.00 46.50  ?  337 ALA A C    1 
ATOM   2943  O O    . ALA A 1 337 ? 133.581 133.820 134.831 1.00 46.50  ?  337 ALA A O    1 
ATOM   2944  C CB   . ALA A 1 337 ? 134.668 136.102 136.993 1.00 46.50  ?  337 ALA A CB   1 
ATOM   2945  H H    . ALA A 1 337 ? 134.596 137.838 135.285 1.00 46.50  ?  337 ALA A H    1 
ATOM   2946  H HA   . ALA A 1 337 ? 135.473 135.372 135.256 1.00 46.50  ?  337 ALA A HA   1 
ATOM   2947  H HB1  . ALA A 1 337 ? 134.654 135.244 137.445 1.00 46.50  ?  337 ALA A HB1  1 
ATOM   2948  H HB2  . ALA A 1 337 ? 135.469 136.592 137.238 1.00 46.50  ?  337 ALA A HB2  1 
ATOM   2949  H HB3  . ALA A 1 337 ? 133.880 136.615 137.231 1.00 46.50  ?  337 ALA A HB3  1 
ATOM   2950  N N    . LYS A 1 338 ? 132.295 135.666 134.966 1.00 44.97  ?  338 LYS A N    1 
ATOM   2951  C CA   . LYS A 1 338 ? 131.089 134.948 134.570 1.00 44.97  ?  338 LYS A CA   1 
ATOM   2952  C C    . LYS A 1 338 ? 131.263 134.311 133.199 1.00 44.97  ?  338 LYS A C    1 
ATOM   2953  O O    . LYS A 1 338 ? 130.975 133.123 133.007 1.00 44.97  ?  338 LYS A O    1 
ATOM   2954  C CB   . LYS A 1 338 ? 129.895 135.905 134.565 1.00 44.97  ?  338 LYS A CB   1 
ATOM   2955  C CG   . LYS A 1 338 ? 129.422 136.326 135.945 1.00 44.97  ?  338 LYS A CG   1 
ATOM   2956  C CD   . LYS A 1 338 ? 128.515 137.550 135.877 1.00 44.97  ?  338 LYS A CD   1 
ATOM   2957  C CE   . LYS A 1 338 ? 127.277 137.303 135.024 1.00 44.97  ?  338 LYS A CE   1 
ATOM   2958  N NZ   . LYS A 1 338 ? 126.397 138.502 134.963 1.00 44.97  1  338 LYS A NZ   1 
ATOM   2959  H H    . LYS A 1 338 ? 132.176 136.504 135.123 1.00 44.97  ?  338 LYS A H    1 
ATOM   2960  H HA   . LYS A 1 338 ? 130.911 134.244 135.212 1.00 44.97  ?  338 LYS A HA   1 
ATOM   2961  H HB2  . LYS A 1 338 ? 130.143 136.708 134.080 1.00 44.97  ?  338 LYS A HB2  1 
ATOM   2962  H HB3  . LYS A 1 338 ? 129.153 135.469 134.118 1.00 44.97  ?  338 LYS A HB3  1 
ATOM   2963  H HG2  . LYS A 1 338 ? 128.921 135.599 136.347 1.00 44.97  ?  338 LYS A HG2  1 
ATOM   2964  H HG3  . LYS A 1 338 ? 130.190 136.548 136.494 1.00 44.97  ?  338 LYS A HG3  1 
ATOM   2965  H HD2  . LYS A 1 338 ? 128.223 137.779 136.773 1.00 44.97  ?  338 LYS A HD2  1 
ATOM   2966  H HD3  . LYS A 1 338 ? 129.007 138.289 135.487 1.00 44.97  ?  338 LYS A HD3  1 
ATOM   2967  H HE2  . LYS A 1 338 ? 127.547 137.087 134.118 1.00 44.97  ?  338 LYS A HE2  1 
ATOM   2968  H HE3  . LYS A 1 338 ? 126.767 136.572 135.404 1.00 44.97  ?  338 LYS A HE3  1 
ATOM   2969  H HZ1  . LYS A 1 338 ? 126.129 138.724 135.782 1.00 44.97  ?  338 LYS A HZ1  1 
ATOM   2970  H HZ2  . LYS A 1 338 ? 126.840 139.187 134.608 1.00 44.97  ?  338 LYS A HZ2  1 
ATOM   2971  H HZ3  . LYS A 1 338 ? 125.682 138.329 134.461 1.00 44.97  ?  338 LYS A HZ3  1 
ATOM   2972  N N    . TYR A 1 339 ? 131.751 135.088 132.230 1.00 43.82  ?  339 TYR A N    1 
ATOM   2973  C CA   . TYR A 1 339 ? 131.899 134.559 130.881 1.00 43.82  ?  339 TYR A CA   1 
ATOM   2974  C C    . TYR A 1 339 ? 133.047 133.563 130.792 1.00 43.82  ?  339 TYR A C    1 
ATOM   2975  O O    . TYR A 1 339 ? 132.995 132.642 129.973 1.00 43.82  ?  339 TYR A O    1 
ATOM   2976  C CB   . TYR A 1 339 ? 132.088 135.702 129.887 1.00 43.82  ?  339 TYR A CB   1 
ATOM   2977  C CG   . TYR A 1 339 ? 130.774 136.255 129.382 1.00 43.82  ?  339 TYR A CG   1 
ATOM   2978  C CD1  . TYR A 1 339 ? 130.159 135.715 128.260 1.00 43.82  ?  339 TYR A CD1  1 
ATOM   2979  C CD2  . TYR A 1 339 ? 130.140 137.302 130.037 1.00 43.82  ?  339 TYR A CD2  1 
ATOM   2980  C CE1  . TYR A 1 339 ? 128.954 136.210 127.799 1.00 43.82  ?  339 TYR A CE1  1 
ATOM   2981  C CE2  . TYR A 1 339 ? 128.935 137.803 129.582 1.00 43.82  ?  339 TYR A CE2  1 
ATOM   2982  C CZ   . TYR A 1 339 ? 128.347 137.253 128.464 1.00 43.82  ?  339 TYR A CZ   1 
ATOM   2983  O OH   . TYR A 1 339 ? 127.147 137.749 128.007 1.00 43.82  ?  339 TYR A OH   1 
ATOM   2984  H H    . TYR A 1 339 ? 131.997 135.906 132.328 1.00 43.82  ?  339 TYR A H    1 
ATOM   2985  H HA   . TYR A 1 339 ? 131.084 134.091 130.641 1.00 43.82  ?  339 TYR A HA   1 
ATOM   2986  H HB2  . TYR A 1 339 ? 132.570 136.423 130.320 1.00 43.82  ?  339 TYR A HB2  1 
ATOM   2987  H HB3  . TYR A 1 339 ? 132.590 135.378 129.123 1.00 43.82  ?  339 TYR A HB3  1 
ATOM   2988  H HD1  . TYR A 1 339 ? 130.566 135.011 127.810 1.00 43.82  ?  339 TYR A HD1  1 
ATOM   2989  H HD2  . TYR A 1 339 ? 130.535 137.675 130.792 1.00 43.82  ?  339 TYR A HD2  1 
ATOM   2990  H HE1  . TYR A 1 339 ? 128.556 135.840 127.044 1.00 43.82  ?  339 TYR A HE1  1 
ATOM   2991  H HE2  . TYR A 1 339 ? 128.523 138.507 130.029 1.00 43.82  ?  339 TYR A HE2  1 
ATOM   2992  H HH   . TYR A 1 339 ? 126.893 137.313 127.336 1.00 43.82  ?  339 TYR A HH   1 
ATOM   2993  N N    . PHE A 1 340 ? 134.075 133.708 131.631 1.00 43.51  ?  340 PHE A N    1 
ATOM   2994  C CA   . PHE A 1 340 ? 135.126 132.699 131.678 1.00 43.51  ?  340 PHE A CA   1 
ATOM   2995  C C    . PHE A 1 340 ? 134.564 131.358 132.127 1.00 43.51  ?  340 PHE A C    1 
ATOM   2996  O O    . PHE A 1 340 ? 134.857 130.317 131.530 1.00 43.51  ?  340 PHE A O    1 
ATOM   2997  C CB   . PHE A 1 340 ? 136.246 133.151 132.615 1.00 43.51  ?  340 PHE A CB   1 
ATOM   2998  C CG   . PHE A 1 340 ? 137.272 132.089 132.887 1.00 43.51  ?  340 PHE A CG   1 
ATOM   2999  C CD1  . PHE A 1 340 ? 138.077 131.607 131.868 1.00 43.51  ?  340 PHE A CD1  1 
ATOM   3000  C CD2  . PHE A 1 340 ? 137.431 131.570 134.161 1.00 43.51  ?  340 PHE A CD2  1 
ATOM   3001  C CE1  . PHE A 1 340 ? 139.021 130.629 132.115 1.00 43.51  ?  340 PHE A CE1  1 
ATOM   3002  C CE2  . PHE A 1 340 ? 138.374 130.592 134.414 1.00 43.51  ?  340 PHE A CE2  1 
ATOM   3003  C CZ   . PHE A 1 340 ? 139.170 130.121 133.389 1.00 43.51  ?  340 PHE A CZ   1 
ATOM   3004  H H    . PHE A 1 340 ? 134.183 134.368 132.171 1.00 43.51  ?  340 PHE A H    1 
ATOM   3005  H HA   . PHE A 1 340 ? 135.501 132.587 130.791 1.00 43.51  ?  340 PHE A HA   1 
ATOM   3006  H HB2  . PHE A 1 340 ? 136.701 133.909 132.218 1.00 43.51  ?  340 PHE A HB2  1 
ATOM   3007  H HB3  . PHE A 1 340 ? 135.856 133.411 133.465 1.00 43.51  ?  340 PHE A HB3  1 
ATOM   3008  H HD1  . PHE A 1 340 ? 137.981 131.946 131.008 1.00 43.51  ?  340 PHE A HD1  1 
ATOM   3009  H HD2  . PHE A 1 340 ? 136.897 131.884 134.855 1.00 43.51  ?  340 PHE A HD2  1 
ATOM   3010  H HE1  . PHE A 1 340 ? 139.556 130.314 131.423 1.00 43.51  ?  340 PHE A HE1  1 
ATOM   3011  H HE2  . PHE A 1 340 ? 138.472 130.252 135.274 1.00 43.51  ?  340 PHE A HE2  1 
ATOM   3012  H HZ   . PHE A 1 340 ? 139.805 129.463 133.558 1.00 43.51  ?  340 PHE A HZ   1 
ATOM   3013  N N    . ILE A 1 341 ? 133.739 131.367 133.177 1.00 39.60  ?  341 ILE A N    1 
ATOM   3014  C CA   . ILE A 1 341 ? 133.118 130.126 133.638 1.00 39.60  ?  341 ILE A CA   1 
ATOM   3015  C C    . ILE A 1 341 ? 132.199 129.565 132.558 1.00 39.60  ?  341 ILE A C    1 
ATOM   3016  O O    . ILE A 1 341 ? 132.188 128.356 132.285 1.00 39.60  ?  341 ILE A O    1 
ATOM   3017  C CB   . ILE A 1 341 ? 132.362 130.361 134.958 1.00 39.60  ?  341 ILE A CB   1 
ATOM   3018  C CG1  . ILE A 1 341 ? 133.330 130.821 136.052 1.00 39.60  ?  341 ILE A CG1  1 
ATOM   3019  C CG2  . ILE A 1 341 ? 131.638 129.090 135.388 1.00 39.60  ?  341 ILE A CG2  1 
ATOM   3020  C CD1  . ILE A 1 341 ? 132.646 131.390 137.278 1.00 39.60  ?  341 ILE A CD1  1 
ATOM   3021  H H    . ILE A 1 341 ? 133.526 132.066 133.631 1.00 39.60  ?  341 ILE A H    1 
ATOM   3022  H HA   . ILE A 1 341 ? 133.814 129.471 133.806 1.00 39.60  ?  341 ILE A HA   1 
ATOM   3023  H HB   . ILE A 1 341 ? 131.703 131.058 134.816 1.00 39.60  ?  341 ILE A HB   1 
ATOM   3024  H HG12 . ILE A 1 341 ? 133.862 130.062 136.336 1.00 39.60  ?  341 ILE A HG12 1 
ATOM   3025  H HG13 . ILE A 1 341 ? 133.910 131.511 135.693 1.00 39.60  ?  341 ILE A HG13 1 
ATOM   3026  H HG21 . ILE A 1 341 ? 130.878 128.943 134.804 1.00 39.60  ?  341 ILE A HG21 1 
ATOM   3027  H HG22 . ILE A 1 341 ? 131.332 129.193 136.302 1.00 39.60  ?  341 ILE A HG22 1 
ATOM   3028  H HG23 . ILE A 1 341 ? 132.253 128.342 135.328 1.00 39.60  ?  341 ILE A HG23 1 
ATOM   3029  H HD11 . ILE A 1 341 ? 133.316 131.789 137.855 1.00 39.60  ?  341 ILE A HD11 1 
ATOM   3030  H HD12 . ILE A 1 341 ? 132.006 132.063 136.998 1.00 39.60  ?  341 ILE A HD12 1 
ATOM   3031  H HD13 . ILE A 1 341 ? 132.190 130.674 137.747 1.00 39.60  ?  341 ILE A HD13 1 
ATOM   3032  N N    . ARG A 1 342 ? 131.412 130.440 131.926 1.00 36.91  ?  342 ARG A N    1 
ATOM   3033  C CA   . ARG A 1 342 ? 130.484 129.990 130.894 1.00 36.91  ?  342 ARG A CA   1 
ATOM   3034  C C    . ARG A 1 342 ? 131.228 129.330 129.739 1.00 36.91  ?  342 ARG A C    1 
ATOM   3035  O O    . ARG A 1 342 ? 130.837 128.260 129.263 1.00 36.91  ?  342 ARG A O    1 
ATOM   3036  C CB   . ARG A 1 342 ? 129.651 131.171 130.394 1.00 36.91  ?  342 ARG A CB   1 
ATOM   3037  C CG   . ARG A 1 342 ? 128.481 130.777 129.507 1.00 36.91  ?  342 ARG A CG   1 
ATOM   3038  C CD   . ARG A 1 342 ? 128.072 131.920 128.592 1.00 36.91  ?  342 ARG A CD   1 
ATOM   3039  N NE   . ARG A 1 342 ? 129.081 132.186 127.569 1.00 36.91  ?  342 ARG A NE   1 
ATOM   3040  C CZ   . ARG A 1 342 ? 128.865 132.896 126.466 1.00 36.91  ?  342 ARG A CZ   1 
ATOM   3041  N NH1  . ARG A 1 342 ? 129.848 133.081 125.596 1.00 36.91  1  342 ARG A NH1  1 
ATOM   3042  N NH2  . ARG A 1 342 ? 127.670 133.422 126.229 1.00 36.91  ?  342 ARG A NH2  1 
ATOM   3043  H H    . ARG A 1 342 ? 131.398 131.286 132.076 1.00 36.91  ?  342 ARG A H    1 
ATOM   3044  H HA   . ARG A 1 342 ? 129.879 129.335 131.275 1.00 36.91  ?  342 ARG A HA   1 
ATOM   3045  H HB2  . ARG A 1 342 ? 129.294 131.645 131.161 1.00 36.91  ?  342 ARG A HB2  1 
ATOM   3046  H HB3  . ARG A 1 342 ? 130.226 131.762 129.882 1.00 36.91  ?  342 ARG A HB3  1 
ATOM   3047  H HG2  . ARG A 1 342 ? 128.732 130.021 128.955 1.00 36.91  ?  342 ARG A HG2  1 
ATOM   3048  H HG3  . ARG A 1 342 ? 127.720 130.548 130.064 1.00 36.91  ?  342 ARG A HG3  1 
ATOM   3049  H HD2  . ARG A 1 342 ? 127.242 131.688 128.147 1.00 36.91  ?  342 ARG A HD2  1 
ATOM   3050  H HD3  . ARG A 1 342 ? 127.956 132.725 129.119 1.00 36.91  ?  342 ARG A HD3  1 
ATOM   3051  H HE   . ARG A 1 342 ? 129.868 131.861 127.689 1.00 36.91  ?  342 ARG A HE   1 
ATOM   3052  H HH11 . ARG A 1 342 ? 130.624 132.742 125.745 1.00 36.91  ?  342 ARG A HH11 1 
ATOM   3053  H HH12 . ARG A 1 342 ? 129.709 133.541 124.882 1.00 36.91  ?  342 ARG A HH12 1 
ATOM   3054  H HH21 . ARG A 1 342 ? 127.027 133.307 126.788 1.00 36.91  ?  342 ARG A HH21 1 
ATOM   3055  H HH22 . ARG A 1 342 ? 127.538 133.880 125.513 1.00 36.91  ?  342 ARG A HH22 1 
ATOM   3056  N N    . ASP A 1 343 ? 132.316 129.951 129.280 1.00 37.85  ?  343 ASP A N    1 
ATOM   3057  C CA   . ASP A 1 343 ? 133.084 129.397 128.174 1.00 37.85  ?  343 ASP A CA   1 
ATOM   3058  C C    . ASP A 1 343 ? 133.845 128.140 128.574 1.00 37.85  ?  343 ASP A C    1 
ATOM   3059  O O    . ASP A 1 343 ? 134.010 127.241 127.743 1.00 37.85  ?  343 ASP A O    1 
ATOM   3060  C CB   . ASP A 1 343 ? 134.053 130.449 127.634 1.00 37.85  ?  343 ASP A CB   1 
ATOM   3061  C CG   . ASP A 1 343 ? 133.356 131.737 127.246 1.00 37.85  ?  343 ASP A CG   1 
ATOM   3062  O OD1  . ASP A 1 343 ? 132.162 131.684 126.884 1.00 37.85  ?  343 ASP A OD1  1 
ATOM   3063  O OD2  . ASP A 1 343 ? 134.003 132.804 127.302 1.00 37.85  -1 343 ASP A OD2  1 
ATOM   3064  H H    . ASP A 1 343 ? 132.626 130.690 129.592 1.00 37.85  ?  343 ASP A H    1 
ATOM   3065  H HA   . ASP A 1 343 ? 132.474 129.159 127.458 1.00 37.85  ?  343 ASP A HA   1 
ATOM   3066  H HB2  . ASP A 1 343 ? 134.716 130.652 128.312 1.00 37.85  ?  343 ASP A HB2  1 
ATOM   3067  H HB3  . ASP A 1 343 ? 134.481 130.100 126.839 1.00 37.85  ?  343 ASP A HB3  1 
ATOM   3068  N N    . GLU A 1 344 ? 134.310 128.055 129.823 1.00 35.14  ?  344 GLU A N    1 
ATOM   3069  C CA   . GLU A 1 344 ? 134.917 126.818 130.297 1.00 35.14  ?  344 GLU A CA   1 
ATOM   3070  C C    . GLU A 1 344 ? 133.918 125.671 130.260 1.00 35.14  ?  344 GLU A C    1 
ATOM   3071  O O    . GLU A 1 344 ? 134.275 124.549 129.885 1.00 35.14  ?  344 GLU A O    1 
ATOM   3072  C CB   . GLU A 1 344 ? 135.459 127.009 131.714 1.00 35.14  ?  344 GLU A CB   1 
ATOM   3073  C CG   . GLU A 1 344 ? 136.168 125.790 132.288 1.00 35.14  ?  344 GLU A CG   1 
ATOM   3074  C CD   . GLU A 1 344 ? 137.436 125.441 131.533 1.00 35.14  ?  344 GLU A CD   1 
ATOM   3075  O OE1  . GLU A 1 344 ? 138.032 126.350 130.918 1.00 35.14  ?  344 GLU A OE1  1 
ATOM   3076  O OE2  . GLU A 1 344 ? 137.836 124.259 131.555 1.00 35.14  -1 344 GLU A OE2  1 
ATOM   3077  H H    . GLU A 1 344 ? 134.285 128.689 130.404 1.00 35.14  ?  344 GLU A H    1 
ATOM   3078  H HA   . GLU A 1 344 ? 135.662 126.590 129.720 1.00 35.14  ?  344 GLU A HA   1 
ATOM   3079  H HB2  . GLU A 1 344 ? 136.093 127.743 131.708 1.00 35.14  ?  344 GLU A HB2  1 
ATOM   3080  H HB3  . GLU A 1 344 ? 134.718 127.222 132.303 1.00 35.14  ?  344 GLU A HB3  1 
ATOM   3081  H HG2  . GLU A 1 344 ? 136.410 125.972 133.209 1.00 35.14  ?  344 GLU A HG2  1 
ATOM   3082  H HG3  . GLU A 1 344 ? 135.574 125.024 132.249 1.00 35.14  ?  344 GLU A HG3  1 
ATOM   3083  N N    . PHE A 1 345 ? 132.669 125.929 130.653 1.00 30.68  ?  345 PHE A N    1 
ATOM   3084  C CA   . PHE A 1 345 ? 131.640 124.901 130.528 1.00 30.68  ?  345 PHE A CA   1 
ATOM   3085  C C    . PHE A 1 345 ? 131.343 124.587 129.065 1.00 30.68  ?  345 PHE A C    1 
ATOM   3086  O O    . PHE A 1 345 ? 131.158 123.421 128.699 1.00 30.68  ?  345 PHE A O    1 
ATOM   3087  C CB   . PHE A 1 345 ? 130.368 125.339 131.253 1.00 30.68  ?  345 PHE A CB   1 
ATOM   3088  C CG   . PHE A 1 345 ? 130.321 124.919 132.693 1.00 30.68  ?  345 PHE A CG   1 
ATOM   3089  C CD1  . PHE A 1 345 ? 129.798 123.687 133.051 1.00 30.68  ?  345 PHE A CD1  1 
ATOM   3090  C CD2  . PHE A 1 345 ? 130.803 125.751 133.689 1.00 30.68  ?  345 PHE A CD2  1 
ATOM   3091  C CE1  . PHE A 1 345 ? 129.754 123.296 134.375 1.00 30.68  ?  345 PHE A CE1  1 
ATOM   3092  C CE2  . PHE A 1 345 ? 130.762 125.364 135.014 1.00 30.68  ?  345 PHE A CE2  1 
ATOM   3093  C CZ   . PHE A 1 345 ? 130.237 124.135 135.357 1.00 30.68  ?  345 PHE A CZ   1 
ATOM   3094  H H    . PHE A 1 345 ? 132.399 126.674 130.987 1.00 30.68  ?  345 PHE A H    1 
ATOM   3095  H HA   . PHE A 1 345 ? 131.957 124.086 130.948 1.00 30.68  ?  345 PHE A HA   1 
ATOM   3096  H HB2  . PHE A 1 345 ? 130.307 126.306 131.223 1.00 30.68  ?  345 PHE A HB2  1 
ATOM   3097  H HB3  . PHE A 1 345 ? 129.603 124.947 130.805 1.00 30.68  ?  345 PHE A HB3  1 
ATOM   3098  H HD1  . PHE A 1 345 ? 129.471 123.118 132.392 1.00 30.68  ?  345 PHE A HD1  1 
ATOM   3099  H HD2  . PHE A 1 345 ? 131.158 126.580 133.463 1.00 30.68  ?  345 PHE A HD2  1 
ATOM   3100  H HE1  . PHE A 1 345 ? 129.399 122.467 134.603 1.00 30.68  ?  345 PHE A HE1  1 
ATOM   3101  H HE2  . PHE A 1 345 ? 131.088 125.932 135.675 1.00 30.68  ?  345 PHE A HE2  1 
ATOM   3102  H HZ   . PHE A 1 345 ? 130.208 123.873 136.249 1.00 30.68  ?  345 PHE A HZ   1 
ATOM   3103  N N    . LEU A 1 346 ? 131.292 125.616 128.214 1.00 31.86  ?  346 LEU A N    1 
ATOM   3104  C CA   . LEU A 1 346 ? 130.929 125.411 126.815 1.00 31.86  ?  346 LEU A CA   1 
ATOM   3105  C C    . LEU A 1 346 ? 131.971 124.592 126.063 1.00 31.86  ?  346 LEU A C    1 
ATOM   3106  O O    . LEU A 1 346 ? 131.610 123.748 125.234 1.00 31.86  ?  346 LEU A O    1 
ATOM   3107  C CB   . LEU A 1 346 ? 130.730 126.759 126.121 1.00 31.86  ?  346 LEU A CB   1 
ATOM   3108  C CG   . LEU A 1 346 ? 129.461 127.534 126.481 1.00 31.86  ?  346 LEU A CG   1 
ATOM   3109  C CD1  . LEU A 1 346 ? 129.478 128.912 125.839 1.00 31.86  ?  346 LEU A CD1  1 
ATOM   3110  C CD2  . LEU A 1 346 ? 128.224 126.760 126.051 1.00 31.86  ?  346 LEU A CD2  1 
ATOM   3111  H H    . LEU A 1 346 ? 131.463 126.433 128.422 1.00 31.86  ?  346 LEU A H    1 
ATOM   3112  H HA   . LEU A 1 346 ? 130.090 124.926 126.777 1.00 31.86  ?  346 LEU A HA   1 
ATOM   3113  H HB2  . LEU A 1 346 ? 131.485 127.327 126.340 1.00 31.86  ?  346 LEU A HB2  1 
ATOM   3114  H HB3  . LEU A 1 346 ? 130.711 126.607 125.163 1.00 31.86  ?  346 LEU A HB3  1 
ATOM   3115  H HG   . LEU A 1 346 ? 129.421 127.650 127.443 1.00 31.86  ?  346 LEU A HG   1 
ATOM   3116  H HD11 . LEU A 1 346 ? 130.255 129.398 126.157 1.00 31.86  ?  346 LEU A HD11 1 
ATOM   3117  H HD12 . LEU A 1 346 ? 129.521 128.810 124.876 1.00 31.86  ?  346 LEU A HD12 1 
ATOM   3118  H HD13 . LEU A 1 346 ? 128.668 129.385 126.087 1.00 31.86  ?  346 LEU A HD13 1 
ATOM   3119  H HD21 . LEU A 1 346 ? 128.070 126.037 126.679 1.00 31.86  ?  346 LEU A HD21 1 
ATOM   3120  H HD22 . LEU A 1 346 ? 128.370 126.402 125.162 1.00 31.86  ?  346 LEU A HD22 1 
ATOM   3121  H HD23 . LEU A 1 346 ? 127.463 127.359 126.045 1.00 31.86  ?  346 LEU A HD23 1 
ATOM   3122  N N    . ARG A 1 347 ? 133.259 124.823 126.327 1.00 32.71  ?  347 ARG A N    1 
ATOM   3123  C CA   . ARG A 1 347 ? 134.298 124.164 125.542 1.00 32.71  ?  347 ARG A CA   1 
ATOM   3124  C C    . ARG A 1 347 ? 134.190 122.646 125.596 1.00 32.71  ?  347 ARG A C    1 
ATOM   3125  O O    . ARG A 1 347 ? 134.645 121.973 124.665 1.00 32.71  ?  347 ARG A O    1 
ATOM   3126  C CB   . ARG A 1 347 ? 135.685 124.601 126.019 1.00 32.71  ?  347 ARG A CB   1 
ATOM   3127  C CG   . ARG A 1 347 ? 135.928 124.431 127.507 1.00 32.71  ?  347 ARG A CG   1 
ATOM   3128  C CD   . ARG A 1 347 ? 137.410 124.276 127.811 1.00 32.71  ?  347 ARG A CD   1 
ATOM   3129  N NE   . ARG A 1 347 ? 137.868 122.900 127.639 1.00 32.71  ?  347 ARG A NE   1 
ATOM   3130  C CZ   . ARG A 1 347 ? 137.600 121.909 128.485 1.00 32.71  ?  347 ARG A CZ   1 
ATOM   3131  N NH1  . ARG A 1 347 ? 138.061 120.689 128.242 1.00 32.71  1  347 ARG A NH1  1 
ATOM   3132  N NH2  . ARG A 1 347 ? 136.877 122.133 129.574 1.00 32.71  ?  347 ARG A NH2  1 
ATOM   3133  H H    . ARG A 1 347 ? 133.551 125.347 126.943 1.00 32.71  ?  347 ARG A H    1 
ATOM   3134  H HA   . ARG A 1 347 ? 134.206 124.433 124.615 1.00 32.71  ?  347 ARG A HA   1 
ATOM   3135  H HB2  . ARG A 1 347 ? 136.353 124.075 125.552 1.00 32.71  ?  347 ARG A HB2  1 
ATOM   3136  H HB3  . ARG A 1 347 ? 135.804 125.540 125.808 1.00 32.71  ?  347 ARG A HB3  1 
ATOM   3137  H HG2  . ARG A 1 347 ? 135.604 125.217 127.972 1.00 32.71  ?  347 ARG A HG2  1 
ATOM   3138  H HG3  . ARG A 1 347 ? 135.466 123.638 127.823 1.00 32.71  ?  347 ARG A HG3  1 
ATOM   3139  H HD2  . ARG A 1 347 ? 137.918 124.839 127.207 1.00 32.71  ?  347 ARG A HD2  1 
ATOM   3140  H HD3  . ARG A 1 347 ? 137.577 124.538 128.730 1.00 32.71  ?  347 ARG A HD3  1 
ATOM   3141  H HE   . ARG A 1 347 ? 138.402 122.735 126.986 1.00 32.71  ?  347 ARG A HE   1 
ATOM   3142  H HH11 . ARG A 1 347 ? 138.531 120.540 127.538 1.00 32.71  ?  347 ARG A HH11 1 
ATOM   3143  H HH12 . ARG A 1 347 ? 137.889 120.048 128.789 1.00 32.71  ?  347 ARG A HH12 1 
ATOM   3144  H HH21 . ARG A 1 347 ? 136.574 122.921 129.739 1.00 32.71  ?  347 ARG A HH21 1 
ATOM   3145  H HH22 . ARG A 1 347 ? 136.708 121.488 130.116 1.00 32.71  ?  347 ARG A HH22 1 
ATOM   3146  N N    . ILE A 1 348 ? 133.602 122.093 126.656 1.00 28.92  ?  348 ILE A N    1 
ATOM   3147  C CA   . ILE A 1 348 ? 133.387 120.652 126.720 1.00 28.92  ?  348 ILE A CA   1 
ATOM   3148  C C    . ILE A 1 348 ? 132.297 120.231 125.743 1.00 28.92  ?  348 ILE A C    1 
ATOM   3149  O O    . ILE A 1 348 ? 132.443 119.246 125.011 1.00 28.92  ?  348 ILE A O    1 
ATOM   3150  C CB   . ILE A 1 348 ? 133.044 120.228 128.160 1.00 28.92  ?  348 ILE A CB   1 
ATOM   3151  C CG1  . ILE A 1 348 ? 134.186 120.594 129.112 1.00 28.92  ?  348 ILE A CG1  1 
ATOM   3152  C CG2  . ILE A 1 348 ? 132.767 118.735 128.218 1.00 28.92  ?  348 ILE A CG2  1 
ATOM   3153  C CD1  . ILE A 1 348 ? 133.794 120.578 130.576 1.00 28.92  ?  348 ILE A CD1  1 
ATOM   3154  H H    . ILE A 1 348 ? 133.322 122.527 127.344 1.00 28.92  ?  348 ILE A H    1 
ATOM   3155  H HA   . ILE A 1 348 ? 134.206 120.201 126.464 1.00 28.92  ?  348 ILE A HA   1 
ATOM   3156  H HB   . ILE A 1 348 ? 132.245 120.702 128.440 1.00 28.92  ?  348 ILE A HB   1 
ATOM   3157  H HG12 . ILE A 1 348 ? 134.909 119.959 128.992 1.00 28.92  ?  348 ILE A HG12 1 
ATOM   3158  H HG13 . ILE A 1 348 ? 134.496 121.489 128.904 1.00 28.92  ?  348 ILE A HG13 1 
ATOM   3159  H HG21 . ILE A 1 348 ? 132.768 118.454 129.145 1.00 28.92  ?  348 ILE A HG21 1 
ATOM   3160  H HG22 . ILE A 1 348 ? 131.902 118.554 127.821 1.00 28.92  ?  348 ILE A HG22 1 
ATOM   3161  H HG23 . ILE A 1 348 ? 133.463 118.266 127.731 1.00 28.92  ?  348 ILE A HG23 1 
ATOM   3162  H HD11 . ILE A 1 348 ? 134.533 120.919 131.103 1.00 28.92  ?  348 ILE A HD11 1 
ATOM   3163  H HD12 . ILE A 1 348 ? 133.593 119.667 130.841 1.00 28.92  ?  348 ILE A HD12 1 
ATOM   3164  H HD13 . ILE A 1 348 ? 133.013 121.139 130.700 1.00 28.92  ?  348 ILE A HD13 1 
ATOM   3165  N N    . SER A 1 349 ? 131.187 120.972 125.717 1.00 27.05  ?  349 SER A N    1 
ATOM   3166  C CA   . SER A 1 349 ? 130.060 120.597 124.868 1.00 27.05  ?  349 SER A CA   1 
ATOM   3167  C C    . SER A 1 349 ? 130.370 120.838 123.395 1.00 27.05  ?  349 SER A C    1 
ATOM   3168  O O    . SER A 1 349 ? 130.100 119.982 122.545 1.00 27.05  ?  349 SER A O    1 
ATOM   3169  C CB   . SER A 1 349 ? 128.812 121.373 125.289 1.00 27.05  ?  349 SER A CB   1 
ATOM   3170  O OG   . SER A 1 349 ? 129.052 122.769 125.273 1.00 27.05  ?  349 SER A OG   1 
ATOM   3171  H H    . SER A 1 349 ? 131.064 121.688 126.176 1.00 27.05  ?  349 SER A H    1 
ATOM   3172  H HA   . SER A 1 349 ? 129.880 119.651 124.985 1.00 27.05  ?  349 SER A HA   1 
ATOM   3173  H HB2  . SER A 1 349 ? 128.092 121.171 124.672 1.00 27.05  ?  349 SER A HB2  1 
ATOM   3174  H HB3  . SER A 1 349 ? 128.563 121.106 126.188 1.00 27.05  ?  349 SER A HB3  1 
ATOM   3175  H HG   . SER A 1 349 ? 128.360 123.182 125.510 1.00 27.05  ?  349 SER A HG   1 
ATOM   3176  N N    . THR A 1 350 ? 130.935 122.004 123.073 1.00 30.75  ?  350 THR A N    1 
ATOM   3177  C CA   . THR A 1 350 ? 131.190 122.338 121.675 1.00 30.75  ?  350 THR A CA   1 
ATOM   3178  C C    . THR A 1 350 ? 132.223 121.401 121.060 1.00 30.75  ?  350 THR A C    1 
ATOM   3179  O O    . THR A 1 350 ? 132.242 121.202 119.839 1.00 30.75  ?  350 THR A O    1 
ATOM   3180  C CB   . THR A 1 350 ? 131.653 123.790 121.557 1.00 30.75  ?  350 THR A CB   1 
ATOM   3181  O OG1  . THR A 1 350 ? 132.837 123.985 122.341 1.00 30.75  ?  350 THR A OG1  1 
ATOM   3182  C CG2  . THR A 1 350 ? 130.564 124.740 122.038 1.00 30.75  ?  350 THR A CG2  1 
ATOM   3183  H H    . THR A 1 350 ? 131.176 122.607 123.636 1.00 30.75  ?  350 THR A H    1 
ATOM   3184  H HA   . THR A 1 350 ? 130.365 122.244 121.173 1.00 30.75  ?  350 THR A HA   1 
ATOM   3185  H HB   . THR A 1 350 ? 131.845 123.992 120.628 1.00 30.75  ?  350 THR A HB   1 
ATOM   3186  H HG1  . THR A 1 350 ? 132.675 123.827 123.149 1.00 30.75  ?  350 THR A HG1  1 
ATOM   3187  H HG21 . THR A 1 350 ? 130.853 125.659 121.924 1.00 30.75  ?  350 THR A HG21 1 
ATOM   3188  H HG22 . THR A 1 350 ? 130.377 124.582 122.976 1.00 30.75  ?  350 THR A HG22 1 
ATOM   3189  H HG23 . THR A 1 350 ? 129.752 124.599 121.526 1.00 30.75  ?  350 THR A HG23 1 
ATOM   3190  N N    . ALA A 1 351 ? 133.092 120.817 121.888 1.00 30.27  ?  351 ALA A N    1 
ATOM   3191  C CA   . ALA A 1 351 ? 134.143 119.949 121.371 1.00 30.27  ?  351 ALA A CA   1 
ATOM   3192  C C    . ALA A 1 351 ? 133.587 118.719 120.666 1.00 30.27  ?  351 ALA A C    1 
ATOM   3193  O O    . ALA A 1 351 ? 134.266 118.156 119.801 1.00 30.27  ?  351 ALA A O    1 
ATOM   3194  C CB   . ALA A 1 351 ? 135.071 119.519 122.507 1.00 30.27  ?  351 ALA A CB   1 
ATOM   3195  H H    . ALA A 1 351 ? 133.093 120.907 122.743 1.00 30.27  ?  351 ALA A H    1 
ATOM   3196  H HA   . ALA A 1 351 ? 134.671 120.447 120.727 1.00 30.27  ?  351 ALA A HA   1 
ATOM   3197  H HB1  . ALA A 1 351 ? 135.763 118.941 122.147 1.00 30.27  ?  351 ALA A HB1  1 
ATOM   3198  H HB2  . ALA A 1 351 ? 135.472 120.309 122.902 1.00 30.27  ?  351 ALA A HB2  1 
ATOM   3199  H HB3  . ALA A 1 351 ? 134.554 119.041 123.173 1.00 30.27  ?  351 ALA A HB3  1 
ATOM   3200  N N    . SER A 1 352 ? 132.373 118.286 121.015 1.00 32.34  ?  352 SER A N    1 
ATOM   3201  C CA   . SER A 1 352 ? 131.809 117.096 120.385 1.00 32.34  ?  352 SER A CA   1 
ATOM   3202  C C    . SER A 1 352 ? 131.621 117.289 118.885 1.00 32.34  ?  352 SER A C    1 
ATOM   3203  O O    . SER A 1 352 ? 132.007 116.417 118.098 1.00 32.34  ?  352 SER A O    1 
ATOM   3204  C CB   . SER A 1 352 ? 130.476 116.738 121.041 1.00 32.34  ?  352 SER A CB   1 
ATOM   3205  O OG   . SER A 1 352 ? 129.533 117.784 120.884 1.00 32.34  ?  352 SER A OG   1 
ATOM   3206  H H    . SER A 1 352 ? 131.866 118.656 121.603 1.00 32.34  ?  352 SER A H    1 
ATOM   3207  H HA   . SER A 1 352 ? 132.417 116.352 120.517 1.00 32.34  ?  352 SER A HA   1 
ATOM   3208  H HB2  . SER A 1 352 ? 130.127 115.934 120.626 1.00 32.34  ?  352 SER A HB2  1 
ATOM   3209  H HB3  . SER A 1 352 ? 130.622 116.585 121.988 1.00 32.34  ?  352 SER A HB3  1 
ATOM   3210  H HG   . SER A 1 352 ? 129.824 118.488 121.238 1.00 32.34  ?  352 SER A HG   1 
ATOM   3211  N N    . GLY A 1 353 ? 131.037 118.411 118.472 1.00 33.71  ?  353 GLY A N    1 
ATOM   3212  C CA   . GLY A 1 353 ? 130.843 118.699 117.067 1.00 33.71  ?  353 GLY A CA   1 
ATOM   3213  C C    . GLY A 1 353 ? 129.786 117.868 116.376 1.00 33.71  ?  353 GLY A C    1 
ATOM   3214  O O    . GLY A 1 353 ? 129.615 118.006 115.159 1.00 33.71  ?  353 GLY A O    1 
ATOM   3215  H H    . GLY A 1 353 ? 130.743 119.025 118.998 1.00 33.71  ?  353 GLY A H    1 
ATOM   3216  H HA2  . GLY A 1 353 ? 130.598 119.633 116.969 1.00 33.71  ?  353 GLY A HA2  1 
ATOM   3217  H HA3  . GLY A 1 353 ? 131.682 118.560 116.601 1.00 33.71  ?  353 GLY A HA3  1 
ATOM   3218  N N    . ASP A 1 354 ? 129.070 117.009 117.104 1.00 33.22  ?  354 ASP A N    1 
ATOM   3219  C CA   . ASP A 1 354 ? 128.056 116.167 116.479 1.00 33.22  ?  354 ASP A CA   1 
ATOM   3220  C C    . ASP A 1 354 ? 126.801 116.951 116.118 1.00 33.22  ?  354 ASP A C    1 
ATOM   3221  O O    . ASP A 1 354 ? 126.207 116.705 115.062 1.00 33.22  ?  354 ASP A O    1 
ATOM   3222  C CB   . ASP A 1 354 ? 127.694 115.006 117.407 1.00 33.22  ?  354 ASP A CB   1 
ATOM   3223  C CG   . ASP A 1 354 ? 128.797 113.970 117.503 1.00 33.22  ?  354 ASP A CG   1 
ATOM   3224  O OD1  . ASP A 1 354 ? 129.667 113.937 116.606 1.00 33.22  ?  354 ASP A OD1  1 
ATOM   3225  O OD2  . ASP A 1 354 ? 128.795 113.186 118.475 1.00 33.22  -1 354 ASP A OD2  1 
ATOM   3226  H H    . ASP A 1 354 ? 129.152 116.897 117.953 1.00 33.22  ?  354 ASP A H    1 
ATOM   3227  H HA   . ASP A 1 354 ? 128.419 115.795 115.660 1.00 33.22  ?  354 ASP A HA   1 
ATOM   3228  H HB2  . ASP A 1 354 ? 127.530 115.353 118.298 1.00 33.22  ?  354 ASP A HB2  1 
ATOM   3229  H HB3  . ASP A 1 354 ? 126.898 114.567 117.069 1.00 33.22  ?  354 ASP A HB3  1 
ATOM   3230  N N    . GLY A 1 355 ? 126.385 117.887 116.968 1.00 27.76  ?  355 GLY A N    1 
ATOM   3231  C CA   . GLY A 1 355 ? 125.170 118.635 116.719 1.00 27.76  ?  355 GLY A CA   1 
ATOM   3232  C C    . GLY A 1 355 ? 123.894 117.901 117.056 1.00 27.76  ?  355 GLY A C    1 
ATOM   3233  O O    . GLY A 1 355 ? 122.808 118.426 116.797 1.00 27.76  ?  355 GLY A O    1 
ATOM   3234  H H    . GLY A 1 355 ? 126.791 118.103 117.694 1.00 27.76  ?  355 GLY A H    1 
ATOM   3235  H HA2  . GLY A 1 355 ? 125.192 119.453 117.240 1.00 27.76  ?  355 GLY A HA2  1 
ATOM   3236  H HA3  . GLY A 1 355 ? 125.137 118.879 115.780 1.00 27.76  ?  355 GLY A HA3  1 
ATOM   3237  N N    . ARG A 1 356 ? 123.991 116.698 117.627 1.00 27.33  ?  356 ARG A N    1 
ATOM   3238  C CA   . ARG A 1 356 ? 122.792 115.950 117.989 1.00 27.33  ?  356 ARG A CA   1 
ATOM   3239  C C    . ARG A 1 356 ? 122.122 116.533 119.227 1.00 27.33  ?  356 ARG A C    1 
ATOM   3240  O O    . ARG A 1 356 ? 120.895 116.461 119.357 1.00 27.33  ?  356 ARG A O    1 
ATOM   3241  C CB   . ARG A 1 356 ? 123.148 114.482 118.215 1.00 27.33  ?  356 ARG A CB   1 
ATOM   3242  C CG   . ARG A 1 356 ? 122.062 113.507 117.793 1.00 27.33  ?  356 ARG A CG   1 
ATOM   3243  C CD   . ARG A 1 356 ? 122.430 112.042 118.048 1.00 27.33  ?  356 ARG A CD   1 
ATOM   3244  N NE   . ARG A 1 356 ? 123.637 111.607 117.343 1.00 27.33  ?  356 ARG A NE   1 
ATOM   3245  C CZ   . ARG A 1 356 ? 124.884 111.803 117.767 1.00 27.33  ?  356 ARG A CZ   1 
ATOM   3246  N NH1  . ARG A 1 356 ? 125.902 111.368 117.037 1.00 27.33  1  356 ARG A NH1  1 
ATOM   3247  N NH2  . ARG A 1 356 ? 125.123 112.402 118.926 1.00 27.33  ?  356 ARG A NH2  1 
ATOM   3248  H H    . ARG A 1 356 ? 124.730 116.299 117.812 1.00 27.33  ?  356 ARG A H    1 
ATOM   3249  H HA   . ARG A 1 356 ? 122.158 115.995 117.256 1.00 27.33  ?  356 ARG A HA   1 
ATOM   3250  H HB2  . ARG A 1 356 ? 123.944 114.281 117.699 1.00 27.33  ?  356 ARG A HB2  1 
ATOM   3251  H HB3  . ARG A 1 356 ? 123.321 114.346 119.159 1.00 27.33  ?  356 ARG A HB3  1 
ATOM   3252  H HG2  . ARG A 1 356 ? 121.254 113.703 118.291 1.00 27.33  ?  356 ARG A HG2  1 
ATOM   3253  H HG3  . ARG A 1 356 ? 121.898 113.612 116.843 1.00 27.33  ?  356 ARG A HG3  1 
ATOM   3254  H HD2  . ARG A 1 356 ? 122.581 111.919 118.998 1.00 27.33  ?  356 ARG A HD2  1 
ATOM   3255  H HD3  . ARG A 1 356 ? 121.696 111.479 117.756 1.00 27.33  ?  356 ARG A HD3  1 
ATOM   3256  H HE   . ARG A 1 356 ? 123.533 111.190 116.599 1.00 27.33  ?  356 ARG A HE   1 
ATOM   3257  H HH11 . ARG A 1 356 ? 125.756 110.974 116.287 1.00 27.33  ?  356 ARG A HH11 1 
ATOM   3258  H HH12 . ARG A 1 356 ? 126.709 111.485 117.311 1.00 27.33  ?  356 ARG A HH12 1 
ATOM   3259  H HH21 . ARG A 1 356 ? 124.473 112.686 119.410 1.00 27.33  ?  356 ARG A HH21 1 
ATOM   3260  H HH22 . ARG A 1 356 ? 125.933 112.515 119.190 1.00 27.33  ?  356 ARG A HH22 1 
ATOM   3261  N N    . HIS A 1 357 ? 122.904 117.108 120.139 1.00 22.31  ?  357 HIS A N    1 
ATOM   3262  C CA   . HIS A 1 357 ? 122.367 117.756 121.325 1.00 22.31  ?  357 HIS A CA   1 
ATOM   3263  C C    . HIS A 1 357 ? 123.147 119.038 121.570 1.00 22.31  ?  357 HIS A C    1 
ATOM   3264  O O    . HIS A 1 357 ? 124.303 119.165 121.155 1.00 22.31  ?  357 HIS A O    1 
ATOM   3265  C CB   . HIS A 1 357 ? 122.433 116.839 122.555 1.00 22.31  ?  357 HIS A CB   1 
ATOM   3266  C CG   . HIS A 1 357 ? 123.806 116.325 122.858 1.00 22.31  ?  357 HIS A CG   1 
ATOM   3267  N ND1  . HIS A 1 357 ? 124.582 115.674 121.923 1.00 22.31  ?  357 HIS A ND1  1 
ATOM   3268  C CD2  . HIS A 1 357 ? 124.539 116.360 123.996 1.00 22.31  ?  357 HIS A CD2  1 
ATOM   3269  C CE1  . HIS A 1 357 ? 125.735 115.334 122.471 1.00 22.31  ?  357 HIS A CE1  1 
ATOM   3270  N NE2  . HIS A 1 357 ? 125.734 115.738 123.728 1.00 22.31  ?  357 HIS A NE2  1 
ATOM   3271  H H    . HIS A 1 357 ? 123.762 117.134 120.088 1.00 22.31  ?  357 HIS A H    1 
ATOM   3272  H HA   . HIS A 1 357 ? 121.438 117.991 121.172 1.00 22.31  ?  357 HIS A HA   1 
ATOM   3273  H HB2  . HIS A 1 357 ? 122.124 117.334 123.330 1.00 22.31  ?  357 HIS A HB2  1 
ATOM   3274  H HB3  . HIS A 1 357 ? 121.857 116.073 122.404 1.00 22.31  ?  357 HIS A HB3  1 
ATOM   3275  H HD2  . HIS A 1 357 ? 124.282 116.736 124.807 1.00 22.31  ?  357 HIS A HD2  1 
ATOM   3276  H HE1  . HIS A 1 357 ? 126.429 114.885 122.044 1.00 22.31  ?  357 HIS A HE1  1 
ATOM   3277  H HE2  . HIS A 1 357 ? 126.378 115.630 124.288 1.00 22.31  ?  357 HIS A HE2  1 
ATOM   3278  N N    . TYR A 1 358 ? 122.505 119.987 122.247 1.00 23.48  ?  358 TYR A N    1 
ATOM   3279  C CA   . TYR A 1 358 ? 123.065 121.313 122.452 1.00 23.48  ?  358 TYR A CA   1 
ATOM   3280  C C    . TYR A 1 358 ? 122.974 121.694 123.923 1.00 23.48  ?  358 TYR A C    1 
ATOM   3281  O O    . TYR A 1 358 ? 122.124 121.197 124.666 1.00 23.48  ?  358 TYR A O    1 
ATOM   3282  C CB   . TYR A 1 358 ? 122.341 122.363 121.597 1.00 23.48  ?  358 TYR A CB   1 
ATOM   3283  C CG   . TYR A 1 358 ? 122.464 122.130 120.108 1.00 23.48  ?  358 TYR A CG   1 
ATOM   3284  C CD1  . TYR A 1 358 ? 123.630 122.452 119.428 1.00 23.48  ?  358 TYR A CD1  1 
ATOM   3285  C CD2  . TYR A 1 358 ? 121.412 121.587 119.383 1.00 23.48  ?  358 TYR A CD2  1 
ATOM   3286  C CE1  . TYR A 1 358 ? 123.746 122.239 118.068 1.00 23.48  ?  358 TYR A CE1  1 
ATOM   3287  C CE2  . TYR A 1 358 ? 121.518 121.371 118.023 1.00 23.48  ?  358 TYR A CE2  1 
ATOM   3288  C CZ   . TYR A 1 358 ? 122.687 121.699 117.370 1.00 23.48  ?  358 TYR A CZ   1 
ATOM   3289  O OH   . TYR A 1 358 ? 122.797 121.485 116.015 1.00 23.48  ?  358 TYR A OH   1 
ATOM   3290  H H    . TYR A 1 358 ? 121.729 119.882 122.603 1.00 23.48  ?  358 TYR A H    1 
ATOM   3291  H HA   . TYR A 1 358 ? 124.001 121.311 122.199 1.00 23.48  ?  358 TYR A HA   1 
ATOM   3292  H HB2  . TYR A 1 358 ? 121.398 122.352 121.822 1.00 23.48  ?  358 TYR A HB2  1 
ATOM   3293  H HB3  . TYR A 1 358 ? 122.715 123.237 121.792 1.00 23.48  ?  358 TYR A HB3  1 
ATOM   3294  H HD1  . TYR A 1 358 ? 124.346 122.817 119.896 1.00 23.48  ?  358 TYR A HD1  1 
ATOM   3295  H HD2  . TYR A 1 358 ? 120.622 121.364 119.821 1.00 23.48  ?  358 TYR A HD2  1 
ATOM   3296  H HE1  . TYR A 1 358 ? 124.533 122.460 117.625 1.00 23.48  ?  358 TYR A HE1  1 
ATOM   3297  H HE2  . TYR A 1 358 ? 120.805 121.006 117.550 1.00 23.48  ?  358 TYR A HE2  1 
ATOM   3298  H HH   . TYR A 1 358 ? 122.084 121.155 115.718 1.00 23.48  ?  358 TYR A HH   1 
ATOM   3299  N N    . CYS A 1 359 ? 123.868 122.589 124.333 1.00 24.56  ?  359 CYS A N    1 
ATOM   3300  C CA   . CYS A 1 359 ? 123.912 123.112 125.692 1.00 24.56  ?  359 CYS A CA   1 
ATOM   3301  C C    . CYS A 1 359 ? 123.399 124.544 125.690 1.00 24.56  ?  359 CYS A C    1 
ATOM   3302  O O    . CYS A 1 359 ? 123.655 125.298 124.744 1.00 24.56  ?  359 CYS A O    1 
ATOM   3303  C CB   . CYS A 1 359 ? 125.333 123.057 126.256 1.00 24.56  ?  359 CYS A CB   1 
ATOM   3304  S SG   . CYS A 1 359 ? 125.488 123.698 127.939 1.00 24.56  ?  359 CYS A SG   1 
ATOM   3305  H H    . CYS A 1 359 ? 124.478 122.918 123.824 1.00 24.56  ?  359 CYS A H    1 
ATOM   3306  H HA   . CYS A 1 359 ? 123.336 122.580 126.263 1.00 24.56  ?  359 CYS A HA   1 
ATOM   3307  H HB2  . CYS A 1 359 ? 125.630 122.134 126.263 1.00 24.56  ?  359 CYS A HB2  1 
ATOM   3308  H HB3  . CYS A 1 359 ? 125.915 123.583 125.685 1.00 24.56  ?  359 CYS A HB3  1 
ATOM   3309  H HG   . CYS A 1 359 ? 124.785 123.054 128.668 1.00 24.56  ?  359 CYS A HG   1 
ATOM   3310  N N    . TYR A 1 360 ? 122.676 124.917 126.747 1.00 24.51  ?  360 TYR A N    1 
ATOM   3311  C CA   . TYR A 1 360 ? 122.040 126.229 126.860 1.00 24.51  ?  360 TYR A CA   1 
ATOM   3312  C C    . TYR A 1 360 ? 122.445 126.867 128.183 1.00 24.51  ?  360 TYR A C    1 
ATOM   3313  O O    . TYR A 1 360 ? 121.695 126.796 129.170 1.00 24.51  ?  360 TYR A O    1 
ATOM   3314  C CB   . TYR A 1 360 ? 120.522 126.109 126.759 1.00 24.51  ?  360 TYR A CB   1 
ATOM   3315  C CG   . TYR A 1 360 ? 120.036 125.437 125.495 1.00 24.51  ?  360 TYR A CG   1 
ATOM   3316  C CD1  . TYR A 1 360 ? 120.042 124.054 125.374 1.00 24.51  ?  360 TYR A CD1  1 
ATOM   3317  C CD2  . TYR A 1 360 ? 119.567 126.185 124.423 1.00 24.51  ?  360 TYR A CD2  1 
ATOM   3318  C CE1  . TYR A 1 360 ? 119.598 123.435 124.221 1.00 24.51  ?  360 TYR A CE1  1 
ATOM   3319  C CE2  . TYR A 1 360 ? 119.120 125.575 123.267 1.00 24.51  ?  360 TYR A CE2  1 
ATOM   3320  C CZ   . TYR A 1 360 ? 119.138 124.200 123.171 1.00 24.51  ?  360 TYR A CZ   1 
ATOM   3321  O OH   . TYR A 1 360 ? 118.694 123.587 122.022 1.00 24.51  ?  360 TYR A OH   1 
ATOM   3322  H H    . TYR A 1 360 ? 122.536 124.412 127.429 1.00 24.51  ?  360 TYR A H    1 
ATOM   3323  H HA   . TYR A 1 360 ? 122.341 126.798 126.135 1.00 24.51  ?  360 TYR A HA   1 
ATOM   3324  H HB2  . TYR A 1 360 ? 120.196 125.594 127.514 1.00 24.51  ?  360 TYR A HB2  1 
ATOM   3325  H HB3  . TYR A 1 360 ? 120.144 127.002 126.782 1.00 24.51  ?  360 TYR A HB3  1 
ATOM   3326  H HD1  . TYR A 1 360 ? 120.352 123.535 126.080 1.00 24.51  ?  360 TYR A HD1  1 
ATOM   3327  H HD2  . TYR A 1 360 ? 119.554 127.113 124.485 1.00 24.51  ?  360 TYR A HD2  1 
ATOM   3328  H HE1  . TYR A 1 360 ? 119.608 122.507 124.154 1.00 24.51  ?  360 TYR A HE1  1 
ATOM   3329  H HE2  . TYR A 1 360 ? 118.809 126.089 122.557 1.00 24.51  ?  360 TYR A HE2  1 
ATOM   3330  H HH   . TYR A 1 360 ? 118.747 122.752 122.104 1.00 24.51  ?  360 TYR A HH   1 
ATOM   3331  N N    . PRO A 1 361 ? 123.616 127.499 128.257 1.00 28.44  ?  361 PRO A N    1 
ATOM   3332  C CA   . PRO A 1 361 ? 124.016 128.159 129.505 1.00 28.44  ?  361 PRO A CA   1 
ATOM   3333  C C    . PRO A 1 361 ? 123.102 129.327 129.840 1.00 28.44  ?  361 PRO A C    1 
ATOM   3334  O O    . PRO A 1 361 ? 122.558 129.994 128.955 1.00 28.44  ?  361 PRO A O    1 
ATOM   3335  C CB   . PRO A 1 361 ? 125.444 128.632 129.211 1.00 28.44  ?  361 PRO A CB   1 
ATOM   3336  C CG   . PRO A 1 361 ? 125.478 128.809 127.738 1.00 28.44  ?  361 PRO A CG   1 
ATOM   3337  C CD   . PRO A 1 361 ? 124.593 127.729 127.178 1.00 28.44  ?  361 PRO A CD   1 
ATOM   3338  H HA   . PRO A 1 361 ? 124.024 127.527 130.241 1.00 28.44  ?  361 PRO A HA   1 
ATOM   3339  H HB2  . PRO A 1 361 ? 125.612 129.473 129.664 1.00 28.44  ?  361 PRO A HB2  1 
ATOM   3340  H HB3  . PRO A 1 361 ? 126.079 127.955 129.492 1.00 28.44  ?  361 PRO A HB3  1 
ATOM   3341  H HG2  . PRO A 1 361 ? 125.132 129.686 127.508 1.00 28.44  ?  361 PRO A HG2  1 
ATOM   3342  H HG3  . PRO A 1 361 ? 126.388 128.708 127.420 1.00 28.44  ?  361 PRO A HG3  1 
ATOM   3343  H HD2  . PRO A 1 361 ? 124.148 128.044 126.376 1.00 28.44  ?  361 PRO A HD2  1 
ATOM   3344  H HD3  . PRO A 1 361 ? 125.107 126.924 127.009 1.00 28.44  ?  361 PRO A HD3  1 
ATOM   3345  N N    . HIS A 1 362 ? 122.937 129.571 131.138 1.00 31.27  ?  362 HIS A N    1 
ATOM   3346  C CA   . HIS A 1 362 ? 122.070 130.638 131.626 1.00 31.27  ?  362 HIS A CA   1 
ATOM   3347  C C    . HIS A 1 362 ? 122.573 131.099 132.984 1.00 31.27  ?  362 HIS A C    1 
ATOM   3348  O O    . HIS A 1 362 ? 122.637 130.302 133.925 1.00 31.27  ?  362 HIS A O    1 
ATOM   3349  C CB   . HIS A 1 362 ? 120.617 130.166 131.732 1.00 31.27  ?  362 HIS A CB   1 
ATOM   3350  C CG   . HIS A 1 362 ? 119.901 130.111 130.419 1.00 31.27  ?  362 HIS A CG   1 
ATOM   3351  N ND1  . HIS A 1 362 ? 119.359 131.227 129.819 1.00 31.27  ?  362 HIS A ND1  1 
ATOM   3352  C CD2  . HIS A 1 362 ? 119.632 129.072 129.592 1.00 31.27  ?  362 HIS A CD2  1 
ATOM   3353  C CE1  . HIS A 1 362 ? 118.790 130.880 128.678 1.00 31.27  ?  362 HIS A CE1  1 
ATOM   3354  N NE2  . HIS A 1 362 ? 118.942 129.577 128.517 1.00 31.27  ?  362 HIS A NE2  1 
ATOM   3355  H H    . HIS A 1 362 ? 123.323 129.125 131.764 1.00 31.27  ?  362 HIS A H    1 
ATOM   3356  H HA   . HIS A 1 362 ? 122.106 131.390 131.014 1.00 31.27  ?  362 HIS A HA   1 
ATOM   3357  H HB2  . HIS A 1 362 ? 120.605 129.275 132.113 1.00 31.27  ?  362 HIS A HB2  1 
ATOM   3358  H HB3  . HIS A 1 362 ? 120.131 130.777 132.309 1.00 31.27  ?  362 HIS A HB3  1 
ATOM   3359  H HD2  . HIS A 1 362 ? 119.871 128.184 129.727 1.00 31.27  ?  362 HIS A HD2  1 
ATOM   3360  H HE1  . HIS A 1 362 ? 118.357 131.454 128.089 1.00 31.27  ?  362 HIS A HE1  1 
ATOM   3361  H HE2  . HIS A 1 362 ? 118.655 129.120 127.848 1.00 31.27  ?  362 HIS A HE2  1 
ATOM   3362  N N    . PHE A 1 363 ? 122.929 132.377 133.086 1.00 38.01  ?  363 PHE A N    1 
ATOM   3363  C CA   . PHE A 1 363 ? 123.274 132.951 134.379 1.00 38.01  ?  363 PHE A CA   1 
ATOM   3364  C C    . PHE A 1 363 ? 122.012 133.085 135.222 1.00 38.01  ?  363 PHE A C    1 
ATOM   3365  O O    . PHE A 1 363 ? 121.046 133.736 134.812 1.00 38.01  ?  363 PHE A O    1 
ATOM   3366  C CB   . PHE A 1 363 ? 123.946 134.310 134.196 1.00 38.01  ?  363 PHE A CB   1 
ATOM   3367  C CG   . PHE A 1 363 ? 125.175 134.265 133.334 1.00 38.01  ?  363 PHE A CG   1 
ATOM   3368  C CD1  . PHE A 1 363 ? 126.292 133.550 133.732 1.00 38.01  ?  363 PHE A CD1  1 
ATOM   3369  C CD2  . PHE A 1 363 ? 125.212 134.934 132.122 1.00 38.01  ?  363 PHE A CD2  1 
ATOM   3370  C CE1  . PHE A 1 363 ? 127.423 133.506 132.940 1.00 38.01  ?  363 PHE A CE1  1 
ATOM   3371  C CE2  . PHE A 1 363 ? 126.340 134.894 131.326 1.00 38.01  ?  363 PHE A CE2  1 
ATOM   3372  C CZ   . PHE A 1 363 ? 127.447 134.178 131.735 1.00 38.01  ?  363 PHE A CZ   1 
ATOM   3373  H H    . PHE A 1 363 ? 122.977 132.928 132.427 1.00 38.01  ?  363 PHE A H    1 
ATOM   3374  H HA   . PHE A 1 363 ? 123.891 132.362 134.841 1.00 38.01  ?  363 PHE A HA   1 
ATOM   3375  H HB2  . PHE A 1 363 ? 123.315 134.919 133.782 1.00 38.01  ?  363 PHE A HB2  1 
ATOM   3376  H HB3  . PHE A 1 363 ? 124.208 134.649 135.067 1.00 38.01  ?  363 PHE A HB3  1 
ATOM   3377  H HD1  . PHE A 1 363 ? 126.281 133.095 134.543 1.00 38.01  ?  363 PHE A HD1  1 
ATOM   3378  H HD2  . PHE A 1 363 ? 124.468 135.418 131.842 1.00 38.01  ?  363 PHE A HD2  1 
ATOM   3379  H HE1  . PHE A 1 363 ? 128.168 133.023 133.218 1.00 38.01  ?  363 PHE A HE1  1 
ATOM   3380  H HE2  . PHE A 1 363 ? 126.354 135.348 130.514 1.00 38.01  ?  363 PHE A HE2  1 
ATOM   3381  H HZ   . PHE A 1 363 ? 128.207 134.150 131.200 1.00 38.01  ?  363 PHE A HZ   1 
ATOM   3382  N N    . THR A 1 364 ? 122.022 132.471 136.403 1.00 38.61  ?  364 THR A N    1 
ATOM   3383  C CA   . THR A 1 364 ? 120.813 132.309 137.195 1.00 38.61  ?  364 THR A CA   1 
ATOM   3384  C C    . THR A 1 364 ? 121.090 132.643 138.653 1.00 38.61  ?  364 THR A C    1 
ATOM   3385  O O    . THR A 1 364 ? 122.212 132.490 139.142 1.00 38.61  ?  364 THR A O    1 
ATOM   3386  C CB   . THR A 1 364 ? 120.271 130.873 137.084 1.00 38.61  ?  364 THR A CB   1 
ATOM   3387  O OG1  . THR A 1 364 ? 119.863 130.615 135.734 1.00 38.61  ?  364 THR A OG1  1 
ATOM   3388  C CG2  . THR A 1 364 ? 119.092 130.657 138.022 1.00 38.61  ?  364 THR A CG2  1 
ATOM   3389  H H    . THR A 1 364 ? 122.725 132.136 136.768 1.00 38.61  ?  364 THR A H    1 
ATOM   3390  H HA   . THR A 1 364 ? 120.130 132.916 136.870 1.00 38.61  ?  364 THR A HA   1 
ATOM   3391  H HB   . THR A 1 364 ? 120.972 130.249 137.329 1.00 38.61  ?  364 THR A HB   1 
ATOM   3392  H HG1  . THR A 1 364 ? 120.518 130.699 135.215 1.00 38.61  ?  364 THR A HG1  1 
ATOM   3393  H HG21 . THR A 1 364 ? 118.612 129.854 137.768 1.00 38.61  ?  364 THR A HG21 1 
ATOM   3394  H HG22 . THR A 1 364 ? 118.489 131.415 137.974 1.00 38.61  ?  364 THR A HG22 1 
ATOM   3395  H HG23 . THR A 1 364 ? 119.405 130.560 138.935 1.00 38.61  ?  364 THR A HG23 1 
ATOM   3396  N N    . CYS A 1 365 ? 120.049 133.110 139.337 1.00 42.94  ?  365 CYS A N    1 
ATOM   3397  C CA   . CYS A 1 365 ? 120.055 133.284 140.780 1.00 42.94  ?  365 CYS A CA   1 
ATOM   3398  C C    . CYS A 1 365 ? 118.956 132.421 141.383 1.00 42.94  ?  365 CYS A C    1 
ATOM   3399  O O    . CYS A 1 365 ? 117.909 132.200 140.766 1.00 42.94  ?  365 CYS A O    1 
ATOM   3400  C CB   . CYS A 1 365 ? 119.847 134.752 141.174 1.00 42.94  ?  365 CYS A CB   1 
ATOM   3401  S SG   . CYS A 1 365 ? 121.254 135.826 140.807 1.00 42.94  ?  365 CYS A SG   1 
ATOM   3402  H H    . CYS A 1 365 ? 119.305 133.340 138.971 1.00 42.94  ?  365 CYS A H    1 
ATOM   3403  H HA   . CYS A 1 365 ? 120.906 132.989 141.139 1.00 42.94  ?  365 CYS A HA   1 
ATOM   3404  H HB2  . CYS A 1 365 ? 119.077 135.098 140.698 1.00 42.94  ?  365 CYS A HB2  1 
ATOM   3405  H HB3  . CYS A 1 365 ? 119.686 134.796 142.130 1.00 42.94  ?  365 CYS A HB3  1 
ATOM   3406  H HG   . CYS A 1 365 ? 120.993 136.944 141.157 1.00 42.94  ?  365 CYS A HG   1 
ATOM   3407  N N    . SER A 1 366 ? 119.203 131.929 142.599 1.00 42.87  ?  366 SER A N    1 
ATOM   3408  C CA   . SER A 1 366 ? 118.256 131.015 143.228 1.00 42.87  ?  366 SER A CA   1 
ATOM   3409  C C    . SER A 1 366 ? 116.877 131.643 143.378 1.00 42.87  ?  366 SER A C    1 
ATOM   3410  O O    . SER A 1 366 ? 115.865 130.933 143.344 1.00 42.87  ?  366 SER A O    1 
ATOM   3411  C CB   . SER A 1 366 ? 118.786 130.570 144.591 1.00 42.87  ?  366 SER A CB   1 
ATOM   3412  H H    . SER A 1 366 ? 119.899 132.107 143.071 1.00 42.87  ?  366 SER A H    1 
ATOM   3413  H HA   . SER A 1 366 ? 118.165 130.226 142.671 1.00 42.87  ?  366 SER A HA   1 
ATOM   3414  H HB2  . SER A 1 366 ? 118.154 129.951 144.988 1.00 42.87  ?  366 SER A HB2  1 
ATOM   3415  H HB3  . SER A 1 366 ? 119.643 130.133 144.468 1.00 42.87  ?  366 SER A HB3  1 
ATOM   3416  N N    . VAL A 1 367 ? 116.811 132.966 143.541 1.00 45.51  ?  367 VAL A N    1 
ATOM   3417  C CA   . VAL A 1 367 ? 115.528 133.628 143.754 1.00 45.51  ?  367 VAL A CA   1 
ATOM   3418  C C    . VAL A 1 367 ? 114.896 134.110 142.453 1.00 45.51  ?  367 VAL A C    1 
ATOM   3419  O O    . VAL A 1 367 ? 113.733 134.535 142.461 1.00 45.51  ?  367 VAL A O    1 
ATOM   3420  C CB   . VAL A 1 367 ? 115.691 134.809 144.726 1.00 45.51  ?  367 VAL A CB   1 
ATOM   3421  C CG1  . VAL A 1 367 ? 116.494 135.933 144.080 1.00 45.51  ?  367 VAL A CG1  1 
ATOM   3422  C CG2  . VAL A 1 367 ? 114.332 135.312 145.196 1.00 45.51  ?  367 VAL A CG2  1 
ATOM   3423  H H    . VAL A 1 367 ? 117.489 133.495 143.533 1.00 45.51  ?  367 VAL A H    1 
ATOM   3424  H HA   . VAL A 1 367 ? 114.915 132.996 144.162 1.00 45.51  ?  367 VAL A HA   1 
ATOM   3425  H HB   . VAL A 1 367 ? 116.181 134.506 145.507 1.00 45.51  ?  367 VAL A HB   1 
ATOM   3426  H HG11 . VAL A 1 367 ? 116.772 136.556 144.769 1.00 45.51  ?  367 VAL A HG11 1 
ATOM   3427  H HG12 . VAL A 1 367 ? 117.273 135.557 143.642 1.00 45.51  ?  367 VAL A HG12 1 
ATOM   3428  H HG13 . VAL A 1 367 ? 115.937 136.389 143.429 1.00 45.51  ?  367 VAL A HG13 1 
ATOM   3429  H HG21 . VAL A 1 367 ? 114.458 135.876 145.975 1.00 45.51  ?  367 VAL A HG21 1 
ATOM   3430  H HG22 . VAL A 1 367 ? 113.918 135.823 144.483 1.00 45.51  ?  367 VAL A HG22 1 
ATOM   3431  H HG23 . VAL A 1 367 ? 113.776 134.551 145.427 1.00 45.51  ?  367 VAL A HG23 1 
ATOM   3432  N N    . ASP A 1 368 ? 115.618 134.054 141.336 1.00 43.09  ?  368 ASP A N    1 
ATOM   3433  C CA   . ASP A 1 368 ? 115.084 134.551 140.073 1.00 43.09  ?  368 ASP A CA   1 
ATOM   3434  C C    . ASP A 1 368 ? 113.812 133.802 139.697 1.00 43.09  ?  368 ASP A C    1 
ATOM   3435  O O    . ASP A 1 368 ? 113.794 132.567 139.658 1.00 43.09  ?  368 ASP A O    1 
ATOM   3436  C CB   . ASP A 1 368 ? 116.128 134.408 138.966 1.00 43.09  ?  368 ASP A CB   1 
ATOM   3437  C CG   . ASP A 1 368 ? 117.068 135.597 138.889 1.00 43.09  ?  368 ASP A CG   1 
ATOM   3438  O OD1  . ASP A 1 368 ? 116.647 136.720 139.238 1.00 43.09  ?  368 ASP A OD1  1 
ATOM   3439  O OD2  . ASP A 1 368 ? 118.231 135.407 138.474 1.00 43.09  -1 368 ASP A OD2  1 
ATOM   3440  H H    . ASP A 1 368 ? 116.415 133.736 141.282 1.00 43.09  ?  368 ASP A H    1 
ATOM   3441  H HA   . ASP A 1 368 ? 114.861 135.490 140.168 1.00 43.09  ?  368 ASP A HA   1 
ATOM   3442  H HB2  . ASP A 1 368 ? 116.660 133.614 139.133 1.00 43.09  ?  368 ASP A HB2  1 
ATOM   3443  H HB3  . ASP A 1 368 ? 115.674 134.329 138.112 1.00 43.09  ?  368 ASP A HB3  1 
ATOM   3444  N N    . THR A 1 369 ? 112.745 134.555 139.419 1.00 44.46  ?  369 THR A N    1 
ATOM   3445  C CA   . THR A 1 369 ? 111.496 133.948 138.975 1.00 44.46  ?  369 THR A CA   1 
ATOM   3446  C C    . THR A 1 369 ? 111.519 133.604 137.492 1.00 44.46  ?  369 THR A C    1 
ATOM   3447  O O    . THR A 1 369 ? 110.663 132.841 137.030 1.00 44.46  ?  369 THR A O    1 
ATOM   3448  C CB   . THR A 1 369 ? 110.322 134.886 139.266 1.00 44.46  ?  369 THR A CB   1 
ATOM   3449  O OG1  . THR A 1 369 ? 110.567 136.164 138.666 1.00 44.46  ?  369 THR A OG1  1 
ATOM   3450  C CG2  . THR A 1 369 ? 110.133 135.059 140.766 1.00 44.46  ?  369 THR A CG2  1 
ATOM   3451  H H    . THR A 1 369 ? 112.722 135.413 139.480 1.00 44.46  ?  369 THR A H    1 
ATOM   3452  H HA   . THR A 1 369 ? 111.352 133.126 139.470 1.00 44.46  ?  369 THR A HA   1 
ATOM   3453  H HB   . THR A 1 369 ? 109.509 134.507 138.897 1.00 44.46  ?  369 THR A HB   1 
ATOM   3454  H HG1  . THR A 1 369 ? 109.927 136.684 138.827 1.00 44.46  ?  369 THR A HG1  1 
ATOM   3455  H HG21 . THR A 1 369 ? 109.386 135.652 140.939 1.00 44.46  ?  369 THR A HG21 1 
ATOM   3456  H HG22 . THR A 1 369 ? 109.956 134.199 141.179 1.00 44.46  ?  369 THR A HG22 1 
ATOM   3457  H HG23 . THR A 1 369 ? 110.935 135.438 141.159 1.00 44.46  ?  369 THR A HG23 1 
ATOM   3458  N N    . GLU A 1 370 ? 112.476 134.148 136.736 1.00 42.39  ?  370 GLU A N    1 
ATOM   3459  C CA   . GLU A 1 370 ? 112.533 133.892 135.302 1.00 42.39  ?  370 GLU A CA   1 
ATOM   3460  C C    . GLU A 1 370 ? 112.946 132.461 134.982 1.00 42.39  ?  370 GLU A C    1 
ATOM   3461  O O    . GLU A 1 370 ? 112.855 132.050 133.820 1.00 42.39  ?  370 GLU A O    1 
ATOM   3462  C CB   . GLU A 1 370 ? 113.504 134.868 134.635 1.00 42.39  ?  370 GLU A CB   1 
ATOM   3463  C CG   . GLU A 1 370 ? 113.068 136.323 134.702 1.00 42.39  ?  370 GLU A CG   1 
ATOM   3464  C CD   . GLU A 1 370 ? 114.074 137.262 134.064 1.00 42.39  ?  370 GLU A CD   1 
ATOM   3465  O OE1  . GLU A 1 370 ? 115.166 136.793 133.679 1.00 42.39  ?  370 GLU A OE1  1 
ATOM   3466  O OE2  . GLU A 1 370 ? 113.772 138.468 133.948 1.00 42.39  -1 370 GLU A OE2  1 
ATOM   3467  H H    . GLU A 1 370 ? 113.099 134.664 137.029 1.00 42.39  ?  370 GLU A H    1 
ATOM   3468  H HA   . GLU A 1 370 ? 111.653 134.040 134.922 1.00 42.39  ?  370 GLU A HA   1 
ATOM   3469  H HB2  . GLU A 1 370 ? 114.366 134.798 135.073 1.00 42.39  ?  370 GLU A HB2  1 
ATOM   3470  H HB3  . GLU A 1 370 ? 113.592 134.629 133.699 1.00 42.39  ?  370 GLU A HB3  1 
ATOM   3471  H HG2  . GLU A 1 370 ? 112.225 136.422 134.233 1.00 42.39  ?  370 GLU A HG2  1 
ATOM   3472  H HG3  . GLU A 1 370 ? 112.964 136.580 135.631 1.00 42.39  ?  370 GLU A HG3  1 
ATOM   3473  N N    . ASN A 1 371 ? 113.394 131.696 135.981 1.00 39.18  ?  371 ASN A N    1 
ATOM   3474  C CA   . ASN A 1 371 ? 113.894 130.350 135.717 1.00 39.18  ?  371 ASN A CA   1 
ATOM   3475  C C    . ASN A 1 371 ? 112.859 129.507 134.983 1.00 39.18  ?  371 ASN A C    1 
ATOM   3476  O O    . ASN A 1 371 ? 113.201 128.751 134.066 1.00 39.18  ?  371 ASN A O    1 
ATOM   3477  C CB   . ASN A 1 371 ? 114.297 129.678 137.028 1.00 39.18  ?  371 ASN A CB   1 
ATOM   3478  C CG   . ASN A 1 371 ? 115.596 130.222 137.582 1.00 39.18  ?  371 ASN A CG   1 
ATOM   3479  O OD1  . ASN A 1 371 ? 116.494 130.596 136.829 1.00 39.18  ?  371 ASN A OD1  1 
ATOM   3480  N ND2  . ASN A 1 371 ? 115.704 130.268 138.905 1.00 39.18  ?  371 ASN A ND2  1 
ATOM   3481  H H    . ASN A 1 371 ? 113.419 131.930 136.808 1.00 39.18  ?  371 ASN A H    1 
ATOM   3482  H HA   . ASN A 1 371 ? 114.682 130.411 135.155 1.00 39.18  ?  371 ASN A HA   1 
ATOM   3483  H HB2  . ASN A 1 371 ? 113.602 129.829 137.688 1.00 39.18  ?  371 ASN A HB2  1 
ATOM   3484  H HB3  . ASN A 1 371 ? 114.410 128.727 136.875 1.00 39.18  ?  371 ASN A HB3  1 
ATOM   3485  H HD21 . ASN A 1 371 ? 115.054 129.998 139.399 1.00 39.18  ?  371 ASN A HD21 1 
ATOM   3486  H HD22 . ASN A 1 371 ? 116.423 130.570 139.268 1.00 39.18  ?  371 ASN A HD22 1 
ATOM   3487  N N    . ILE A 1 372 ? 111.589 129.620 135.373 1.00 38.15  ?  372 ILE A N    1 
ATOM   3488  C CA   . ILE A 1 372 ? 110.536 128.874 134.690 1.00 38.15  ?  372 ILE A CA   1 
ATOM   3489  C C    . ILE A 1 372 ? 110.455 129.300 133.229 1.00 38.15  ?  372 ILE A C    1 
ATOM   3490  O O    . ILE A 1 372 ? 110.381 128.464 132.319 1.00 38.15  ?  372 ILE A O    1 
ATOM   3491  C CB   . ILE A 1 372 ? 109.190 129.071 135.411 1.00 38.15  ?  372 ILE A CB   1 
ATOM   3492  C CG1  . ILE A 1 372 ? 109.271 128.527 136.840 1.00 38.15  ?  372 ILE A CG1  1 
ATOM   3493  C CG2  . ILE A 1 372 ? 108.071 128.391 134.642 1.00 38.15  ?  372 ILE A CG2  1 
ATOM   3494  C CD1  . ILE A 1 372 ? 109.386 129.605 137.900 1.00 38.15  ?  372 ILE A CD1  1 
ATOM   3495  H H    . ILE A 1 372 ? 111.315 130.116 136.019 1.00 38.15  ?  372 ILE A H    1 
ATOM   3496  H HA   . ILE A 1 372 ? 110.753 127.929 134.714 1.00 38.15  ?  372 ILE A HA   1 
ATOM   3497  H HB   . ILE A 1 372 ? 109.001 130.021 135.454 1.00 38.15  ?  372 ILE A HB   1 
ATOM   3498  H HG12 . ILE A 1 372 ? 108.474 128.008 137.029 1.00 38.15  ?  372 ILE A HG12 1 
ATOM   3499  H HG13 . ILE A 1 372 ? 110.055 127.961 136.910 1.00 38.15  ?  372 ILE A HG13 1 
ATOM   3500  H HG21 . ILE A 1 372 ? 107.279 128.353 135.201 1.00 38.15  ?  372 ILE A HG21 1 
ATOM   3501  H HG22 . ILE A 1 372 ? 107.880 128.902 133.840 1.00 38.15  ?  372 ILE A HG22 1 
ATOM   3502  H HG23 . ILE A 1 372 ? 108.352 127.494 134.406 1.00 38.15  ?  372 ILE A HG23 1 
ATOM   3503  H HD11 . ILE A 1 372 ? 110.211 130.097 137.765 1.00 38.15  ?  372 ILE A HD11 1 
ATOM   3504  H HD12 . ILE A 1 372 ? 109.391 129.188 138.775 1.00 38.15  ?  372 ILE A HD12 1 
ATOM   3505  H HD13 . ILE A 1 372 ? 108.627 130.205 137.824 1.00 38.15  ?  372 ILE A HD13 1 
ATOM   3506  N N    . ARG A 1 373 ? 110.479 130.612 132.984 1.00 37.53  ?  373 ARG A N    1 
ATOM   3507  C CA   . ARG A 1 373 ? 110.472 131.105 131.611 1.00 37.53  ?  373 ARG A CA   1 
ATOM   3508  C C    . ARG A 1 373 ? 111.721 130.657 130.865 1.00 37.53  ?  373 ARG A C    1 
ATOM   3509  O O    . ARG A 1 373 ? 111.658 130.325 129.676 1.00 37.53  ?  373 ARG A O    1 
ATOM   3510  C CB   . ARG A 1 373 ? 110.356 132.629 131.600 1.00 37.53  ?  373 ARG A CB   1 
ATOM   3511  C CG   . ARG A 1 373 ? 109.178 133.180 132.397 1.00 37.53  ?  373 ARG A CG   1 
ATOM   3512  C CD   . ARG A 1 373 ? 107.854 132.563 131.963 1.00 37.53  ?  373 ARG A CD   1 
ATOM   3513  N NE   . ARG A 1 373 ? 107.598 132.752 130.538 1.00 37.53  ?  373 ARG A NE   1 
ATOM   3514  C CZ   . ARG A 1 373 ? 106.471 132.404 129.925 1.00 37.53  ?  373 ARG A CZ   1 
ATOM   3515  N NH1  . ARG A 1 373 ? 106.332 132.615 128.623 1.00 37.53  1  373 ARG A NH1  1 
ATOM   3516  N NH2  . ARG A 1 373 ? 105.480 131.845 130.608 1.00 37.53  ?  373 ARG A NH2  1 
ATOM   3517  H H    . ARG A 1 373 ? 110.499 131.225 133.586 1.00 37.53  ?  373 ARG A H    1 
ATOM   3518  H HA   . ARG A 1 373 ? 109.703 130.739 131.147 1.00 37.53  ?  373 ARG A HA   1 
ATOM   3519  H HB2  . ARG A 1 373 ? 111.167 133.005 131.976 1.00 37.53  ?  373 ARG A HB2  1 
ATOM   3520  H HB3  . ARG A 1 373 ? 110.255 132.925 130.682 1.00 37.53  ?  373 ARG A HB3  1 
ATOM   3521  H HG2  . ARG A 1 373 ? 109.308 132.985 133.338 1.00 37.53  ?  373 ARG A HG2  1 
ATOM   3522  H HG3  . ARG A 1 373 ? 109.122 134.139 132.261 1.00 37.53  ?  373 ARG A HG3  1 
ATOM   3523  H HD2  . ARG A 1 373 ? 107.867 131.611 132.146 1.00 37.53  ?  373 ARG A HD2  1 
ATOM   3524  H HD3  . ARG A 1 373 ? 107.133 132.985 132.456 1.00 37.53  ?  373 ARG A HD3  1 
ATOM   3525  H HE   . ARG A 1 373 ? 108.192 133.170 130.076 1.00 37.53  ?  373 ARG A HE   1 
ATOM   3526  H HH11 . ARG A 1 373 ? 106.971 132.977 128.176 1.00 37.53  ?  373 ARG A HH11 1 
ATOM   3527  H HH12 . ARG A 1 373 ? 105.603 132.391 128.227 1.00 37.53  ?  373 ARG A HH12 1 
ATOM   3528  H HH21 . ARG A 1 373 ? 105.561 131.704 131.453 1.00 37.53  ?  373 ARG A HH21 1 
ATOM   3529  H HH22 . ARG A 1 373 ? 104.754 131.624 130.205 1.00 37.53  ?  373 ARG A HH22 1 
ATOM   3530  N N    . ARG A 1 374 ? 112.870 130.643 131.546 1.00 36.22  ?  374 ARG A N    1 
ATOM   3531  C CA   . ARG A 1 374 ? 114.091 130.159 130.912 1.00 36.22  ?  374 ARG A CA   1 
ATOM   3532  C C    . ARG A 1 374 ? 113.942 128.704 130.488 1.00 36.22  ?  374 ARG A C    1 
ATOM   3533  O O    . ARG A 1 374 ? 114.299 128.335 129.365 1.00 36.22  ?  374 ARG A O    1 
ATOM   3534  C CB   . ARG A 1 374 ? 115.279 130.321 131.861 1.00 36.22  ?  374 ARG A CB   1 
ATOM   3535  C CG   . ARG A 1 374 ? 115.635 131.763 132.181 1.00 36.22  ?  374 ARG A CG   1 
ATOM   3536  C CD   . ARG A 1 374 ? 117.049 131.873 132.730 1.00 36.22  ?  374 ARG A CD   1 
ATOM   3537  N NE   . ARG A 1 374 ? 117.129 132.801 133.859 1.00 36.22  ?  374 ARG A NE   1 
ATOM   3538  C CZ   . ARG A 1 374 ? 117.849 133.922 133.883 1.00 36.22  ?  374 ARG A CZ   1 
ATOM   3539  N NH1  . ARG A 1 374 ? 117.839 134.681 134.970 1.00 36.22  1  374 ARG A NH1  1 
ATOM   3540  N NH2  . ARG A 1 374 ? 118.577 134.295 132.837 1.00 36.22  ?  374 ARG A NH2  1 
ATOM   3541  H H    . ARG A 1 374 ? 112.966 130.906 132.359 1.00 36.22  ?  374 ARG A H    1 
ATOM   3542  H HA   . ARG A 1 374 ? 114.267 130.687 130.117 1.00 36.22  ?  374 ARG A HA   1 
ATOM   3543  H HB2  . ARG A 1 374 ? 115.070 129.876 132.697 1.00 36.22  ?  374 ARG A HB2  1 
ATOM   3544  H HB3  . ARG A 1 374 ? 116.058 129.907 131.456 1.00 36.22  ?  374 ARG A HB3  1 
ATOM   3545  H HG2  . ARG A 1 374 ? 115.578 132.296 131.373 1.00 36.22  ?  374 ARG A HG2  1 
ATOM   3546  H HG3  . ARG A 1 374 ? 115.024 132.103 132.852 1.00 36.22  ?  374 ARG A HG3  1 
ATOM   3547  H HD2  . ARG A 1 374 ? 117.330 131.000 133.045 1.00 36.22  ?  374 ARG A HD2  1 
ATOM   3548  H HD3  . ARG A 1 374 ? 117.636 132.169 132.021 1.00 36.22  ?  374 ARG A HD3  1 
ATOM   3549  H HE   . ARG A 1 374 ? 116.679 132.605 134.565 1.00 36.22  ?  374 ARG A HE   1 
ATOM   3550  H HH11 . ARG A 1 374 ? 117.371 134.448 135.653 1.00 36.22  ?  374 ARG A HH11 1 
ATOM   3551  H HH12 . ARG A 1 374 ? 118.301 135.406 134.993 1.00 36.22  ?  374 ARG A HH12 1 
ATOM   3552  H HH21 . ARG A 1 374 ? 118.597 133.819 132.123 1.00 36.22  ?  374 ARG A HH21 1 
ATOM   3553  H HH22 . ARG A 1 374 ? 119.033 135.023 132.875 1.00 36.22  ?  374 ARG A HH22 1 
ATOM   3554  N N    . VAL A 1 375 ? 113.407 127.862 131.375 1.00 31.56  ?  375 VAL A N    1 
ATOM   3555  C CA   . VAL A 1 375 ? 113.241 126.448 131.047 1.00 31.56  ?  375 VAL A CA   1 
ATOM   3556  C C    . VAL A 1 375 ? 112.278 126.288 129.878 1.00 31.56  ?  375 VAL A C    1 
ATOM   3557  O O    . VAL A 1 375 ? 112.498 125.466 128.979 1.00 31.56  ?  375 VAL A O    1 
ATOM   3558  C CB   . VAL A 1 375 ? 112.765 125.666 132.286 1.00 31.56  ?  375 VAL A CB   1 
ATOM   3559  C CG1  . VAL A 1 375 ? 112.477 124.214 131.925 1.00 31.56  ?  375 VAL A CG1  1 
ATOM   3560  C CG2  . VAL A 1 375 ? 113.803 125.750 133.396 1.00 31.56  ?  375 VAL A CG2  1 
ATOM   3561  H H    . VAL A 1 375 ? 113.136 128.082 132.161 1.00 31.56  ?  375 VAL A H    1 
ATOM   3562  H HA   . VAL A 1 375 ? 114.099 126.085 130.777 1.00 31.56  ?  375 VAL A HA   1 
ATOM   3563  H HB   . VAL A 1 375 ? 111.943 126.063 132.613 1.00 31.56  ?  375 VAL A HB   1 
ATOM   3564  H HG11 . VAL A 1 375 ? 111.660 124.170 131.403 1.00 31.56  ?  375 VAL A HG11 1 
ATOM   3565  H HG12 . VAL A 1 375 ? 112.372 123.701 132.742 1.00 31.56  ?  375 VAL A HG12 1 
ATOM   3566  H HG13 . VAL A 1 375 ? 113.220 123.864 131.409 1.00 31.56  ?  375 VAL A HG13 1 
ATOM   3567  H HG21 . VAL A 1 375 ? 114.553 126.283 133.090 1.00 31.56  ?  375 VAL A HG21 1 
ATOM   3568  H HG22 . VAL A 1 375 ? 113.399 126.163 134.175 1.00 31.56  ?  375 VAL A HG22 1 
ATOM   3569  H HG23 . VAL A 1 375 ? 114.104 124.854 133.616 1.00 31.56  ?  375 VAL A HG23 1 
ATOM   3570  N N    . PHE A 1 376 ? 111.193 127.064 129.877 1.00 32.09  ?  376 PHE A N    1 
ATOM   3571  C CA   . PHE A 1 376 ? 110.251 127.025 128.762 1.00 32.09  ?  376 PHE A CA   1 
ATOM   3572  C C    . PHE A 1 376 ? 110.945 127.389 127.454 1.00 32.09  ?  376 PHE A C    1 
ATOM   3573  O O    . PHE A 1 376 ? 110.751 126.729 126.424 1.00 32.09  ?  376 PHE A O    1 
ATOM   3574  C CB   . PHE A 1 376 ? 109.089 127.977 129.052 1.00 32.09  ?  376 PHE A CB   1 
ATOM   3575  C CG   . PHE A 1 376 ? 107.929 127.840 128.107 1.00 32.09  ?  376 PHE A CG   1 
ATOM   3576  C CD1  . PHE A 1 376 ? 107.962 128.431 126.855 1.00 32.09  ?  376 PHE A CD1  1 
ATOM   3577  C CD2  . PHE A 1 376 ? 106.794 127.144 128.483 1.00 32.09  ?  376 PHE A CD2  1 
ATOM   3578  C CE1  . PHE A 1 376 ? 106.890 128.313 125.990 1.00 32.09  ?  376 PHE A CE1  1 
ATOM   3579  C CE2  . PHE A 1 376 ? 105.720 127.022 127.623 1.00 32.09  ?  376 PHE A CE2  1 
ATOM   3580  C CZ   . PHE A 1 376 ? 105.767 127.610 126.376 1.00 32.09  ?  376 PHE A CZ   1 
ATOM   3581  H H    . PHE A 1 376 ? 110.981 127.613 130.504 1.00 32.09  ?  376 PHE A H    1 
ATOM   3582  H HA   . PHE A 1 376 ? 109.894 126.127 128.677 1.00 32.09  ?  376 PHE A HA   1 
ATOM   3583  H HB2  . PHE A 1 376 ? 108.760 127.803 129.948 1.00 32.09  ?  376 PHE A HB2  1 
ATOM   3584  H HB3  . PHE A 1 376 ? 109.412 128.890 128.994 1.00 32.09  ?  376 PHE A HB3  1 
ATOM   3585  H HD1  . PHE A 1 376 ? 108.716 128.906 126.590 1.00 32.09  ?  376 PHE A HD1  1 
ATOM   3586  H HD2  . PHE A 1 376 ? 106.757 126.746 129.323 1.00 32.09  ?  376 PHE A HD2  1 
ATOM   3587  H HE1  . PHE A 1 376 ? 106.924 128.709 125.150 1.00 32.09  ?  376 PHE A HE1  1 
ATOM   3588  H HE2  . PHE A 1 376 ? 104.965 126.547 127.886 1.00 32.09  ?  376 PHE A HE2  1 
ATOM   3589  H HZ   . PHE A 1 376 ? 105.046 127.528 125.796 1.00 32.09  ?  376 PHE A HZ   1 
ATOM   3590  N N    . ASN A 1 377 ? 111.768 128.440 127.480 1.00 32.57  ?  377 ASN A N    1 
ATOM   3591  C CA   . ASN A 1 377 ? 112.469 128.867 126.274 1.00 32.57  ?  377 ASN A CA   1 
ATOM   3592  C C    . ASN A 1 377 ? 113.448 127.802 125.794 1.00 32.57  ?  377 ASN A C    1 
ATOM   3593  O O    . ASN A 1 377 ? 113.549 127.546 124.589 1.00 32.57  ?  377 ASN A O    1 
ATOM   3594  C CB   . ASN A 1 377 ? 113.200 130.184 126.533 1.00 32.57  ?  377 ASN A CB   1 
ATOM   3595  C CG   . ASN A 1 377 ? 112.276 131.385 126.469 1.00 32.57  ?  377 ASN A CG   1 
ATOM   3596  O OD1  . ASN A 1 377 ? 111.787 131.751 125.401 1.00 32.57  ?  377 ASN A OD1  1 
ATOM   3597  N ND2  . ASN A 1 377 ? 112.034 132.007 127.617 1.00 32.57  ?  377 ASN A ND2  1 
ATOM   3598  H H    . ASN A 1 377 ? 111.932 128.918 128.176 1.00 32.57  ?  377 ASN A H    1 
ATOM   3599  H HA   . ASN A 1 377 ? 111.821 129.017 125.568 1.00 32.57  ?  377 ASN A HA   1 
ATOM   3600  H HB2  . ASN A 1 377 ? 113.599 130.158 127.417 1.00 32.57  ?  377 ASN A HB2  1 
ATOM   3601  H HB3  . ASN A 1 377 ? 113.888 130.301 125.860 1.00 32.57  ?  377 ASN A HB3  1 
ATOM   3602  H HD21 . ASN A 1 377 ? 112.395 131.723 128.344 1.00 32.57  ?  377 ASN A HD21 1 
ATOM   3603  H HD22 . ASN A 1 377 ? 111.517 132.694 127.634 1.00 32.57  ?  377 ASN A HD22 1 
ATOM   3604  N N    . ASP A 1 378 ? 114.186 127.177 126.716 1.00 30.05  ?  378 ASP A N    1 
ATOM   3605  C CA   . ASP A 1 378 ? 115.117 126.127 126.310 1.00 30.05  ?  378 ASP A CA   1 
ATOM   3606  C C    . ASP A 1 378 ? 114.379 124.927 125.731 1.00 30.05  ?  378 ASP A C    1 
ATOM   3607  O O    . ASP A 1 378 ? 114.846 124.316 124.765 1.00 30.05  ?  378 ASP A O    1 
ATOM   3608  C CB   . ASP A 1 378 ? 116.009 125.690 127.475 1.00 30.05  ?  378 ASP A CB   1 
ATOM   3609  C CG   . ASP A 1 378 ? 116.825 126.831 128.057 1.00 30.05  ?  378 ASP A CG   1 
ATOM   3610  O OD1  . ASP A 1 378 ? 117.905 127.122 127.506 1.00 30.05  ?  378 ASP A OD1  1 
ATOM   3611  O OD2  . ASP A 1 378 ? 116.395 127.447 129.049 1.00 30.05  -1 378 ASP A OD2  1 
ATOM   3612  H H    . ASP A 1 378 ? 114.166 127.338 127.561 1.00 30.05  ?  378 ASP A H    1 
ATOM   3613  H HA   . ASP A 1 378 ? 115.695 126.478 125.615 1.00 30.05  ?  378 ASP A HA   1 
ATOM   3614  H HB2  . ASP A 1 378 ? 115.449 125.332 128.182 1.00 30.05  ?  378 ASP A HB2  1 
ATOM   3615  H HB3  . ASP A 1 378 ? 116.626 125.010 127.163 1.00 30.05  ?  378 ASP A HB3  1 
ATOM   3616  N N    . CYS A 1 379 ? 113.234 124.562 126.311 1.00 28.61  ?  379 CYS A N    1 
ATOM   3617  C CA   . CYS A 1 379 ? 112.456 123.462 125.745 1.00 28.61  ?  379 CYS A CA   1 
ATOM   3618  C C    . CYS A 1 379 ? 111.980 123.797 124.336 1.00 28.61  ?  379 CYS A C    1 
ATOM   3619  O O    . CYS A 1 379 ? 112.068 122.960 123.425 1.00 28.61  ?  379 CYS A O    1 
ATOM   3620  C CB   . CYS A 1 379 ? 111.269 123.138 126.651 1.00 28.61  ?  379 CYS A CB   1 
ATOM   3621  S SG   . CYS A 1 379 ? 111.718 122.317 128.198 1.00 28.61  ?  379 CYS A SG   1 
ATOM   3622  H H    . CYS A 1 379 ? 112.894 124.924 127.013 1.00 28.61  ?  379 CYS A H    1 
ATOM   3623  H HA   . CYS A 1 379 ? 113.018 122.673 125.692 1.00 28.61  ?  379 CYS A HA   1 
ATOM   3624  H HB2  . CYS A 1 379 ? 110.816 123.966 126.878 1.00 28.61  ?  379 CYS A HB2  1 
ATOM   3625  H HB3  . CYS A 1 379 ? 110.662 122.554 126.172 1.00 28.61  ?  379 CYS A HB3  1 
ATOM   3626  H HG   . CYS A 1 379 ? 112.469 123.019 128.816 1.00 28.61  ?  379 CYS A HG   1 
ATOM   3627  N N    . ARG A 1 380 ? 111.480 125.020 124.137 1.00 28.35  ?  380 ARG A N    1 
ATOM   3628  C CA   . ARG A 1 380 ? 111.062 125.438 122.803 1.00 28.35  ?  380 ARG A CA   1 
ATOM   3629  C C    . ARG A 1 380 ? 112.226 125.372 121.823 1.00 28.35  ?  380 ARG A C    1 
ATOM   3630  O O    . ARG A 1 380 ? 112.083 124.871 120.702 1.00 28.35  ?  380 ARG A O    1 
ATOM   3631  C CB   . ARG A 1 380 ? 110.489 126.855 122.852 1.00 28.35  ?  380 ARG A CB   1 
ATOM   3632  C CG   . ARG A 1 380 ? 109.066 126.938 123.366 1.00 28.35  ?  380 ARG A CG   1 
ATOM   3633  C CD   . ARG A 1 380 ? 108.365 128.173 122.825 1.00 28.35  ?  380 ARG A CD   1 
ATOM   3634  N NE   . ARG A 1 380 ? 109.087 129.399 123.164 1.00 28.35  ?  380 ARG A NE   1 
ATOM   3635  C CZ   . ARG A 1 380 ? 109.856 130.090 122.325 1.00 28.35  ?  380 ARG A CZ   1 
ATOM   3636  N NH1  . ARG A 1 380 ? 110.462 131.192 122.747 1.00 28.35  1  380 ARG A NH1  1 
ATOM   3637  N NH2  . ARG A 1 380 ? 110.031 129.690 121.071 1.00 28.35  ?  380 ARG A NH2  1 
ATOM   3638  H H    . ARG A 1 380 ? 111.375 125.615 124.749 1.00 28.35  ?  380 ARG A H    1 
ATOM   3639  H HA   . ARG A 1 380 ? 110.367 124.841 122.486 1.00 28.35  ?  380 ARG A HA   1 
ATOM   3640  H HB2  . ARG A 1 380 ? 111.045 127.394 123.436 1.00 28.35  ?  380 ARG A HB2  1 
ATOM   3641  H HB3  . ARG A 1 380 ? 110.501 127.225 121.956 1.00 28.35  ?  380 ARG A HB3  1 
ATOM   3642  H HG2  . ARG A 1 380 ? 108.574 126.157 123.068 1.00 28.35  ?  380 ARG A HG2  1 
ATOM   3643  H HG3  . ARG A 1 380 ? 109.073 126.986 124.334 1.00 28.35  ?  380 ARG A HG3  1 
ATOM   3644  H HD2  . ARG A 1 380 ? 108.286 128.101 121.863 1.00 28.35  ?  380 ARG A HD2  1 
ATOM   3645  H HD3  . ARG A 1 380 ? 107.482 128.229 123.221 1.00 28.35  ?  380 ARG A HD3  1 
ATOM   3646  H HE   . ARG A 1 380 ? 109.017 129.691 123.970 1.00 28.35  ?  380 ARG A HE   1 
ATOM   3647  H HH11 . ARG A 1 380 ? 110.355 131.458 123.558 1.00 28.35  ?  380 ARG A HH11 1 
ATOM   3648  H HH12 . ARG A 1 380 ? 110.961 131.640 122.210 1.00 28.35  ?  380 ARG A HH12 1 
ATOM   3649  H HH21 . ARG A 1 380 ? 109.648 128.979 120.781 1.00 28.35  ?  380 ARG A HH21 1 
ATOM   3650  H HH22 . ARG A 1 380 ? 110.533 130.148 120.545 1.00 28.35  ?  380 ARG A HH22 1 
ATOM   3651  N N    . ASP A 1 381 ? 113.390 125.882 122.232 1.00 26.81  ?  381 ASP A N    1 
ATOM   3652  C CA   . ASP A 1 381 ? 114.550 125.878 121.349 1.00 26.81  ?  381 ASP A CA   1 
ATOM   3653  C C    . ASP A 1 381 ? 114.981 124.458 121.013 1.00 26.81  ?  381 ASP A C    1 
ATOM   3654  O O    . ASP A 1 381 ? 115.327 124.164 119.865 1.00 26.81  ?  381 ASP A O    1 
ATOM   3655  C CB   . ASP A 1 381 ? 115.701 126.649 121.995 1.00 26.81  ?  381 ASP A CB   1 
ATOM   3656  C CG   . ASP A 1 381 ? 115.363 128.106 122.237 1.00 26.81  ?  381 ASP A CG   1 
ATOM   3657  O OD1  . ASP A 1 381 ? 114.333 128.575 121.707 1.00 26.81  ?  381 ASP A OD1  1 
ATOM   3658  O OD2  . ASP A 1 381 ? 116.126 128.784 122.957 1.00 26.81  -1 381 ASP A OD2  1 
ATOM   3659  H H    . ASP A 1 381 ? 113.529 126.231 123.005 1.00 26.81  ?  381 ASP A H    1 
ATOM   3660  H HA   . ASP A 1 381 ? 114.318 126.325 120.520 1.00 26.81  ?  381 ASP A HA   1 
ATOM   3661  H HB2  . ASP A 1 381 ? 115.913 126.243 122.851 1.00 26.81  ?  381 ASP A HB2  1 
ATOM   3662  H HB3  . ASP A 1 381 ? 116.474 126.613 121.410 1.00 26.81  ?  381 ASP A HB3  1 
ATOM   3663  N N    . ILE A 1 382 ? 114.969 123.562 122.002 1.00 24.97  ?  382 ILE A N    1 
ATOM   3664  C CA   . ILE A 1 382 ? 115.373 122.181 121.757 1.00 24.97  ?  382 ILE A CA   1 
ATOM   3665  C C    . ILE A 1 382 ? 114.430 121.523 120.761 1.00 24.97  ?  382 ILE A C    1 
ATOM   3666  O O    . ILE A 1 382 ? 114.870 120.862 119.810 1.00 24.97  ?  382 ILE A O    1 
ATOM   3667  C CB   . ILE A 1 382 ? 115.429 121.399 123.083 1.00 24.97  ?  382 ILE A CB   1 
ATOM   3668  C CG1  . ILE A 1 382 ? 116.596 121.891 123.942 1.00 24.97  ?  382 ILE A CG1  1 
ATOM   3669  C CG2  . ILE A 1 382 ? 115.561 119.906 122.818 1.00 24.97  ?  382 ILE A CG2  1 
ATOM   3670  C CD1  . ILE A 1 382 ? 116.445 121.574 125.414 1.00 24.97  ?  382 ILE A CD1  1 
ATOM   3671  H H    . ILE A 1 382 ? 114.734 123.727 122.812 1.00 24.97  ?  382 ILE A H    1 
ATOM   3672  H HA   . ILE A 1 382 ? 116.263 122.178 121.372 1.00 24.97  ?  382 ILE A HA   1 
ATOM   3673  H HB   . ILE A 1 382 ? 114.603 121.554 123.568 1.00 24.97  ?  382 ILE A HB   1 
ATOM   3674  H HG12 . ILE A 1 382 ? 117.412 121.470 123.630 1.00 24.97  ?  382 ILE A HG12 1 
ATOM   3675  H HG13 . ILE A 1 382 ? 116.668 122.854 123.852 1.00 24.97  ?  382 ILE A HG13 1 
ATOM   3676  H HG21 . ILE A 1 382 ? 114.693 119.550 122.574 1.00 24.97  ?  382 ILE A HG21 1 
ATOM   3677  H HG22 . ILE A 1 382 ? 116.192 119.768 122.094 1.00 24.97  ?  382 ILE A HG22 1 
ATOM   3678  H HG23 . ILE A 1 382 ? 115.879 119.470 123.623 1.00 24.97  ?  382 ILE A HG23 1 
ATOM   3679  H HD11 . ILE A 1 382 ? 117.200 121.946 125.896 1.00 24.97  ?  382 ILE A HD11 1 
ATOM   3680  H HD12 . ILE A 1 382 ? 115.619 121.966 125.738 1.00 24.97  ?  382 ILE A HD12 1 
ATOM   3681  H HD13 . ILE A 1 382 ? 116.421 120.611 125.529 1.00 24.97  ?  382 ILE A HD13 1 
ATOM   3682  N N    . ILE A 1 383 ? 113.121 121.692 120.956 1.00 26.66  ?  383 ILE A N    1 
ATOM   3683  C CA   . ILE A 1 383 ? 112.159 121.076 120.044 1.00 26.66  ?  383 ILE A CA   1 
ATOM   3684  C C    . ILE A 1 383 ? 112.320 121.648 118.639 1.00 26.66  ?  383 ILE A C    1 
ATOM   3685  O O    . ILE A 1 383 ? 112.314 120.910 117.644 1.00 26.66  ?  383 ILE A O    1 
ATOM   3686  C CB   . ILE A 1 383 ? 110.724 121.261 120.568 1.00 26.66  ?  383 ILE A CB   1 
ATOM   3687  C CG1  . ILE A 1 383 ? 110.555 120.560 121.918 1.00 26.66  ?  383 ILE A CG1  1 
ATOM   3688  C CG2  . ILE A 1 383 ? 109.720 120.711 119.565 1.00 26.66  ?  383 ILE A CG2  1 
ATOM   3689  C CD1  . ILE A 1 383 ? 109.334 121.008 122.691 1.00 26.66  ?  383 ILE A CD1  1 
ATOM   3690  H H    . ILE A 1 383 ? 112.771 122.148 121.595 1.00 26.66  ?  383 ILE A H    1 
ATOM   3691  H HA   . ILE A 1 383 ? 112.338 120.124 119.998 1.00 26.66  ?  383 ILE A HA   1 
ATOM   3692  H HB   . ILE A 1 383 ? 110.557 122.209 120.687 1.00 26.66  ?  383 ILE A HB   1 
ATOM   3693  H HG12 . ILE A 1 383 ? 110.475 119.606 121.766 1.00 26.66  ?  383 ILE A HG12 1 
ATOM   3694  H HG13 . ILE A 1 383 ? 111.333 120.740 122.468 1.00 26.66  ?  383 ILE A HG13 1 
ATOM   3695  H HG21 . ILE A 1 383 ? 109.677 121.303 118.798 1.00 26.66  ?  383 ILE A HG21 1 
ATOM   3696  H HG22 . ILE A 1 383 ? 108.848 120.656 119.986 1.00 26.66  ?  383 ILE A HG22 1 
ATOM   3697  H HG23 . ILE A 1 383 ? 110.006 119.827 119.286 1.00 26.66  ?  383 ILE A HG23 1 
ATOM   3698  H HD11 . ILE A 1 383 ? 109.354 120.604 123.572 1.00 26.66  ?  383 ILE A HD11 1 
ATOM   3699  H HD12 . ILE A 1 383 ? 108.537 120.726 122.216 1.00 26.66  ?  383 ILE A HD12 1 
ATOM   3700  H HD13 . ILE A 1 383 ? 109.349 121.974 122.770 1.00 26.66  ?  383 ILE A HD13 1 
ATOM   3701  N N    . GLN A 1 384 ? 112.463 122.972 118.537 1.00 25.94  ?  384 GLN A N    1 
ATOM   3702  C CA   . GLN A 1 384 ? 112.594 123.604 117.229 1.00 25.94  ?  384 GLN A CA   1 
ATOM   3703  C C    . GLN A 1 384 ? 113.854 123.132 116.517 1.00 25.94  ?  384 GLN A C    1 
ATOM   3704  O O    . GLN A 1 384 ? 113.830 122.841 115.317 1.00 25.94  ?  384 GLN A O    1 
ATOM   3705  C CB   . GLN A 1 384 ? 112.599 125.125 117.384 1.00 25.94  ?  384 GLN A CB   1 
ATOM   3706  C CG   . GLN A 1 384 ? 111.222 125.726 117.615 1.00 25.94  ?  384 GLN A CG   1 
ATOM   3707  C CD   . GLN A 1 384 ? 111.246 127.241 117.644 1.00 25.94  ?  384 GLN A CD   1 
ATOM   3708  O OE1  . GLN A 1 384 ? 112.310 127.855 117.722 1.00 25.94  ?  384 GLN A OE1  1 
ATOM   3709  N NE2  . GLN A 1 384 ? 110.069 127.853 117.580 1.00 25.94  ?  384 GLN A NE2  1 
ATOM   3710  H H    . GLN A 1 384 ? 112.486 123.517 119.201 1.00 25.94  ?  384 GLN A H    1 
ATOM   3711  H HA   . GLN A 1 384 ? 111.831 123.360 116.682 1.00 25.94  ?  384 GLN A HA   1 
ATOM   3712  H HB2  . GLN A 1 384 ? 113.155 125.359 118.142 1.00 25.94  ?  384 GLN A HB2  1 
ATOM   3713  H HB3  . GLN A 1 384 ? 112.962 125.519 116.575 1.00 25.94  ?  384 GLN A HB3  1 
ATOM   3714  H HG2  . GLN A 1 384 ? 110.631 125.449 116.898 1.00 25.94  ?  384 GLN A HG2  1 
ATOM   3715  H HG3  . GLN A 1 384 ? 110.880 125.415 118.468 1.00 25.94  ?  384 GLN A HG3  1 
ATOM   3716  H HE21 . GLN A 1 384 ? 109.347 127.390 117.526 1.00 25.94  ?  384 GLN A HE21 1 
ATOM   3717  H HE22 . GLN A 1 384 ? 110.030 128.712 117.593 1.00 25.94  ?  384 GLN A HE22 1 
ATOM   3718  N N    . ARG A 1 385 ? 114.973 123.053 117.242 1.00 24.61  ?  385 ARG A N    1 
ATOM   3719  C CA   . ARG A 1 385 ? 116.215 122.591 116.636 1.00 24.61  ?  385 ARG A CA   1 
ATOM   3720  C C    . ARG A 1 385 ? 116.121 121.135 116.205 1.00 24.61  ?  385 ARG A C    1 
ATOM   3721  O O    . ARG A 1 385 ? 116.618 120.778 115.132 1.00 24.61  ?  385 ARG A O    1 
ATOM   3722  C CB   . ARG A 1 385 ? 117.378 122.784 117.610 1.00 24.61  ?  385 ARG A CB   1 
ATOM   3723  C CG   . ARG A 1 385 ? 117.772 124.238 117.811 1.00 24.61  ?  385 ARG A CG   1 
ATOM   3724  C CD   . ARG A 1 385 ? 119.018 124.369 118.668 1.00 24.61  ?  385 ARG A CD   1 
ATOM   3725  N NE   . ARG A 1 385 ? 119.258 125.751 119.073 1.00 24.61  ?  385 ARG A NE   1 
ATOM   3726  C CZ   . ARG A 1 385 ? 120.261 126.141 119.853 1.00 24.61  ?  385 ARG A CZ   1 
ATOM   3727  N NH1  . ARG A 1 385 ? 120.397 127.422 120.166 1.00 24.61  1  385 ARG A NH1  1 
ATOM   3728  N NH2  . ARG A 1 385 ? 121.130 125.255 120.321 1.00 24.61  ?  385 ARG A NH2  1 
ATOM   3729  H H    . ARG A 1 385 ? 115.035 123.259 118.075 1.00 24.61  ?  385 ARG A H    1 
ATOM   3730  H HA   . ARG A 1 385 ? 116.396 123.125 115.846 1.00 24.61  ?  385 ARG A HA   1 
ATOM   3731  H HB2  . ARG A 1 385 ? 117.125 122.423 118.474 1.00 24.61  ?  385 ARG A HB2  1 
ATOM   3732  H HB3  . ARG A 1 385 ? 118.153 122.311 117.269 1.00 24.61  ?  385 ARG A HB3  1 
ATOM   3733  H HG2  . ARG A 1 385 ? 117.956 124.640 116.947 1.00 24.61  ?  385 ARG A HG2  1 
ATOM   3734  H HG3  . ARG A 1 385 ? 117.048 124.709 118.252 1.00 24.61  ?  385 ARG A HG3  1 
ATOM   3735  H HD2  . ARG A 1 385 ? 118.911 123.833 119.470 1.00 24.61  ?  385 ARG A HD2  1 
ATOM   3736  H HD3  . ARG A 1 385 ? 119.787 124.063 118.162 1.00 24.61  ?  385 ARG A HD3  1 
ATOM   3737  H HE   . ARG A 1 385 ? 118.669 126.338 118.857 1.00 24.61  ?  385 ARG A HE   1 
ATOM   3738  H HH11 . ARG A 1 385 ? 119.835 128.000 119.865 1.00 24.61  ?  385 ARG A HH11 1 
ATOM   3739  H HH12 . ARG A 1 385 ? 121.045 127.676 120.671 1.00 24.61  ?  385 ARG A HH12 1 
ATOM   3740  H HH21 . ARG A 1 385 ? 121.049 124.422 120.123 1.00 24.61  ?  385 ARG A HH21 1 
ATOM   3741  H HH22 . ARG A 1 385 ? 121.777 125.514 120.825 1.00 24.61  ?  385 ARG A HH22 1 
ATOM   3742  N N    . MET A 1 386 ? 115.495 120.282 117.019 1.00 28.48  ?  386 MET A N    1 
ATOM   3743  C CA   . MET A 1 386 ? 115.324 118.889 116.620 1.00 28.48  ?  386 MET A CA   1 
ATOM   3744  C C    . MET A 1 386 ? 114.498 118.787 115.345 1.00 28.48  ?  386 MET A C    1 
ATOM   3745  O O    . MET A 1 386 ? 114.863 118.057 114.414 1.00 28.48  ?  386 MET A O    1 
ATOM   3746  C CB   . MET A 1 386 ? 114.665 118.098 117.749 1.00 28.48  ?  386 MET A CB   1 
ATOM   3747  C CG   . MET A 1 386 ? 114.688 116.591 117.541 1.00 28.48  ?  386 MET A CG   1 
ATOM   3748  S SD   . MET A 1 386 ? 113.092 115.909 117.046 1.00 28.48  ?  386 MET A SD   1 
ATOM   3749  C CE   . MET A 1 386 ? 112.080 116.309 118.470 1.00 28.48  ?  386 MET A CE   1 
ATOM   3750  H H    . MET A 1 386 ? 115.170 120.480 117.790 1.00 28.48  ?  386 MET A H    1 
ATOM   3751  H HA   . MET A 1 386 ? 116.198 118.502 116.457 1.00 28.48  ?  386 MET A HA   1 
ATOM   3752  H HB2  . MET A 1 386 ? 115.130 118.290 118.578 1.00 28.48  ?  386 MET A HB2  1 
ATOM   3753  H HB3  . MET A 1 386 ? 113.739 118.376 117.820 1.00 28.48  ?  386 MET A HB3  1 
ATOM   3754  H HG2  . MET A 1 386 ? 115.330 116.379 116.845 1.00 28.48  ?  386 MET A HG2  1 
ATOM   3755  H HG3  . MET A 1 386 ? 114.950 116.163 118.372 1.00 28.48  ?  386 MET A HG3  1 
ATOM   3756  H HE1  . MET A 1 386 ? 112.536 116.014 119.273 1.00 28.48  ?  386 MET A HE1  1 
ATOM   3757  H HE2  . MET A 1 386 ? 111.227 115.855 118.387 1.00 28.48  ?  386 MET A HE2  1 
ATOM   3758  H HE3  . MET A 1 386 ? 111.942 117.268 118.502 1.00 28.48  ?  386 MET A HE3  1 
ATOM   3759  N N    . HIS A 1 387 ? 113.387 119.523 115.276 1.00 27.56  ?  387 HIS A N    1 
ATOM   3760  C CA   . HIS A 1 387 ? 112.548 119.474 114.083 1.00 27.56  ?  387 HIS A CA   1 
ATOM   3761  C C    . HIS A 1 387 ? 113.295 120.008 112.865 1.00 27.56  ?  387 HIS A C    1 
ATOM   3762  O O    . HIS A 1 387 ? 113.203 119.440 111.771 1.00 27.56  ?  387 HIS A O    1 
ATOM   3763  C CB   . HIS A 1 387 ? 111.259 120.262 114.315 1.00 27.56  ?  387 HIS A CB   1 
ATOM   3764  C CG   . HIS A 1 387 ? 110.224 119.513 115.096 1.00 27.56  ?  387 HIS A CG   1 
ATOM   3765  N ND1  . HIS A 1 387 ? 109.385 120.127 116.001 1.00 27.56  ?  387 HIS A ND1  1 
ATOM   3766  C CD2  . HIS A 1 387 ? 109.890 118.200 115.106 1.00 27.56  ?  387 HIS A CD2  1 
ATOM   3767  C CE1  . HIS A 1 387 ? 108.581 119.226 116.535 1.00 27.56  ?  387 HIS A CE1  1 
ATOM   3768  N NE2  . HIS A 1 387 ? 108.867 118.049 116.009 1.00 27.56  ?  387 HIS A NE2  1 
ATOM   3769  H H    . HIS A 1 387 ? 113.103 120.049 115.895 1.00 27.56  ?  387 HIS A H    1 
ATOM   3770  H HA   . HIS A 1 387 ? 112.311 118.551 113.903 1.00 27.56  ?  387 HIS A HA   1 
ATOM   3771  H HB2  . HIS A 1 387 ? 111.469 121.075 114.801 1.00 27.56  ?  387 HIS A HB2  1 
ATOM   3772  H HB3  . HIS A 1 387 ? 110.873 120.483 113.453 1.00 27.56  ?  387 HIS A HB3  1 
ATOM   3773  H HD2  . HIS A 1 387 ? 110.282 117.528 114.597 1.00 27.56  ?  387 HIS A HD2  1 
ATOM   3774  H HE1  . HIS A 1 387 ? 107.925 119.392 117.173 1.00 27.56  ?  387 HIS A HE1  1 
ATOM   3775  H HE2  . HIS A 1 387 ? 108.475 117.307 116.201 1.00 27.56  ?  387 HIS A HE2  1 
ATOM   3776  N N    . LEU A 1 388 ? 114.042 121.101 113.035 1.00 26.17  ?  388 LEU A N    1 
ATOM   3777  C CA   . LEU A 1 388 ? 114.789 121.668 111.917 1.00 26.17  ?  388 LEU A CA   1 
ATOM   3778  C C    . LEU A 1 388 ? 115.849 120.697 111.415 1.00 26.17  ?  388 LEU A C    1 
ATOM   3779  O O    . LEU A 1 388 ? 116.019 120.525 110.203 1.00 26.17  ?  388 LEU A O    1 
ATOM   3780  C CB   . LEU A 1 388 ? 115.431 122.991 112.336 1.00 26.17  ?  388 LEU A CB   1 
ATOM   3781  C CG   . LEU A 1 388 ? 114.469 124.157 112.576 1.00 26.17  ?  388 LEU A CG   1 
ATOM   3782  C CD1  . LEU A 1 388 ? 115.174 125.288 113.309 1.00 26.17  ?  388 LEU A CD1  1 
ATOM   3783  C CD2  . LEU A 1 388 ? 113.881 124.653 111.266 1.00 26.17  ?  388 LEU A CD2  1 
ATOM   3784  H H    . LEU A 1 388 ? 114.130 121.526 113.777 1.00 26.17  ?  388 LEU A H    1 
ATOM   3785  H HA   . LEU A 1 388 ? 114.177 121.848 111.187 1.00 26.17  ?  388 LEU A HA   1 
ATOM   3786  H HB2  . LEU A 1 388 ? 115.919 122.845 113.161 1.00 26.17  ?  388 LEU A HB2  1 
ATOM   3787  H HB3  . LEU A 1 388 ? 116.048 123.264 111.639 1.00 26.17  ?  388 LEU A HB3  1 
ATOM   3788  H HG   . LEU A 1 388 ? 113.736 123.852 113.132 1.00 26.17  ?  388 LEU A HG   1 
ATOM   3789  H HD11 . LEU A 1 388 ? 114.544 126.010 113.454 1.00 26.17  ?  388 LEU A HD11 1 
ATOM   3790  H HD12 . LEU A 1 388 ? 115.917 125.600 112.769 1.00 26.17  ?  388 LEU A HD12 1 
ATOM   3791  H HD13 . LEU A 1 388 ? 115.500 124.956 114.160 1.00 26.17  ?  388 LEU A HD13 1 
ATOM   3792  H HD21 . LEU A 1 388 ? 113.289 123.973 110.909 1.00 26.17  ?  388 LEU A HD21 1 
ATOM   3793  H HD22 . LEU A 1 388 ? 113.384 125.469 111.433 1.00 26.17  ?  388 LEU A HD22 1 
ATOM   3794  H HD23 . LEU A 1 388 ? 114.602 124.828 110.641 1.00 26.17  ?  388 LEU A HD23 1 
ATOM   3795  N N    . ARG A 1 389 ? 116.573 120.051 112.333 1.00 28.18  ?  389 ARG A N    1 
ATOM   3796  C CA   . ARG A 1 389 ? 117.571 119.071 111.923 1.00 28.18  ?  389 ARG A CA   1 
ATOM   3797  C C    . ARG A 1 389 ? 116.922 117.874 111.243 1.00 28.18  ?  389 ARG A C    1 
ATOM   3798  O O    . ARG A 1 389 ? 117.511 117.289 110.327 1.00 28.18  ?  389 ARG A O    1 
ATOM   3799  C CB   . ARG A 1 389 ? 118.390 118.618 113.132 1.00 28.18  ?  389 ARG A CB   1 
ATOM   3800  C CG   . ARG A 1 389 ? 119.576 117.735 112.779 1.00 28.18  ?  389 ARG A CG   1 
ATOM   3801  C CD   . ARG A 1 389 ? 120.402 117.396 114.009 1.00 28.18  ?  389 ARG A CD   1 
ATOM   3802  N NE   . ARG A 1 389 ? 121.528 116.520 113.689 1.00 28.18  ?  389 ARG A NE   1 
ATOM   3803  C CZ   . ARG A 1 389 ? 121.495 115.191 113.743 1.00 28.18  ?  389 ARG A CZ   1 
ATOM   3804  N NH1  . ARG A 1 389 ? 122.578 114.492 113.432 1.00 28.18  1  389 ARG A NH1  1 
ATOM   3805  N NH2  . ARG A 1 389 ? 120.387 114.555 114.102 1.00 28.18  ?  389 ARG A NH2  1 
ATOM   3806  H H    . ARG A 1 389 ? 116.505 120.163 113.183 1.00 28.18  ?  389 ARG A H    1 
ATOM   3807  H HA   . ARG A 1 389 ? 118.177 119.484 111.289 1.00 28.18  ?  389 ARG A HA   1 
ATOM   3808  H HB2  . ARG A 1 389 ? 118.730 119.402 113.590 1.00 28.18  ?  389 ARG A HB2  1 
ATOM   3809  H HB3  . ARG A 1 389 ? 117.814 118.114 113.728 1.00 28.18  ?  389 ARG A HB3  1 
ATOM   3810  H HG2  . ARG A 1 389 ? 119.256 116.906 112.391 1.00 28.18  ?  389 ARG A HG2  1 
ATOM   3811  H HG3  . ARG A 1 389 ? 120.147 118.203 112.149 1.00 28.18  ?  389 ARG A HG3  1 
ATOM   3812  H HD2  . ARG A 1 389 ? 120.761 118.216 114.381 1.00 28.18  ?  389 ARG A HD2  1 
ATOM   3813  H HD3  . ARG A 1 389 ? 119.839 116.957 114.665 1.00 28.18  ?  389 ARG A HD3  1 
ATOM   3814  H HE   . ARG A 1 389 ? 122.267 116.891 113.452 1.00 28.18  ?  389 ARG A HE   1 
ATOM   3815  H HH11 . ARG A 1 389 ? 123.299 114.898 113.199 1.00 28.18  ?  389 ARG A HH11 1 
ATOM   3816  H HH12 . ARG A 1 389 ? 122.560 113.633 113.465 1.00 28.18  ?  389 ARG A HH12 1 
ATOM   3817  H HH21 . ARG A 1 389 ? 119.678 114.995 114.305 1.00 28.18  ?  389 ARG A HH21 1 
ATOM   3818  H HH22 . ARG A 1 389 ? 120.379 113.695 114.132 1.00 28.18  ?  389 ARG A HH22 1 
ATOM   3819  N N    . GLN A 1 390 ? 115.716 117.497 111.672 1.00 28.36  ?  390 GLN A N    1 
ATOM   3820  C CA   . GLN A 1 390 ? 114.991 116.434 110.985 1.00 28.36  ?  390 GLN A CA   1 
ATOM   3821  C C    . GLN A 1 390 ? 114.673 116.834 109.549 1.00 28.36  ?  390 GLN A C    1 
ATOM   3822  O O    . GLN A 1 390 ? 114.750 116.008 108.631 1.00 28.36  ?  390 GLN A O    1 
ATOM   3823  C CB   . GLN A 1 390 ? 113.709 116.097 111.748 1.00 28.36  ?  390 GLN A CB   1 
ATOM   3824  C CG   . GLN A 1 390 ? 113.045 114.806 111.299 1.00 28.36  ?  390 GLN A CG   1 
ATOM   3825  C CD   . GLN A 1 390 ? 111.732 114.548 112.011 1.00 28.36  ?  390 GLN A CD   1 
ATOM   3826  O OE1  . GLN A 1 390 ? 110.660 114.633 111.412 1.00 28.36  ?  390 GLN A OE1  1 
ATOM   3827  N NE2  . GLN A 1 390 ? 111.810 114.231 113.299 1.00 28.36  ?  390 GLN A NE2  1 
ATOM   3828  H H    . GLN A 1 390 ? 115.304 117.836 112.346 1.00 28.36  ?  390 GLN A H    1 
ATOM   3829  H HA   . GLN A 1 390 ? 115.544 115.638 110.960 1.00 28.36  ?  390 GLN A HA   1 
ATOM   3830  H HB2  . GLN A 1 390 ? 113.921 116.009 112.690 1.00 28.36  ?  390 GLN A HB2  1 
ATOM   3831  H HB3  . GLN A 1 390 ? 113.072 116.817 111.621 1.00 28.36  ?  390 GLN A HB3  1 
ATOM   3832  H HG2  . GLN A 1 390 ? 112.865 114.856 110.347 1.00 28.36  ?  390 GLN A HG2  1 
ATOM   3833  H HG3  . GLN A 1 390 ? 113.639 114.062 111.486 1.00 28.36  ?  390 GLN A HG3  1 
ATOM   3834  H HE21 . GLN A 1 390 ? 112.578 114.182 113.684 1.00 28.36  ?  390 GLN A HE21 1 
ATOM   3835  H HE22 . GLN A 1 390 ? 111.093 114.076 113.747 1.00 28.36  ?  390 GLN A HE22 1 
ATOM   3836  N N    . TYR A 1 391 ? 114.315 118.099 109.336 1.00 26.63  ?  391 TYR A N    1 
ATOM   3837  C CA   . TYR A 1 391 ? 113.986 118.611 108.012 1.00 26.63  ?  391 TYR A CA   1 
ATOM   3838  C C    . TYR A 1 391 ? 115.215 119.042 107.219 1.00 26.63  ?  391 TYR A C    1 
ATOM   3839  O O    . TYR A 1 391 ? 115.063 119.649 106.154 1.00 26.63  ?  391 TYR A O    1 
ATOM   3840  C CB   . TYR A 1 391 ? 113.015 119.790 108.134 1.00 26.63  ?  391 TYR A CB   1 
ATOM   3841  C CG   . TYR A 1 391 ? 111.769 119.489 108.940 1.00 26.63  ?  391 TYR A CG   1 
ATOM   3842  C CD1  . TYR A 1 391 ? 111.295 118.189 109.070 1.00 26.63  ?  391 TYR A CD1  1 
ATOM   3843  C CD2  . TYR A 1 391 ? 111.066 120.506 109.572 1.00 26.63  ?  391 TYR A CD2  1 
ATOM   3844  C CE1  . TYR A 1 391 ? 110.159 117.912 109.805 1.00 26.63  ?  391 TYR A CE1  1 
ATOM   3845  C CE2  . TYR A 1 391 ? 109.929 120.239 110.309 1.00 26.63  ?  391 TYR A CE2  1 
ATOM   3846  C CZ   . TYR A 1 391 ? 109.480 118.940 110.422 1.00 26.63  ?  391 TYR A CZ   1 
ATOM   3847  O OH   . TYR A 1 391 ? 108.348 118.668 111.155 1.00 26.63  ?  391 TYR A OH   1 
ATOM   3848  H H    . TYR A 1 391 ? 114.256 118.690 109.958 1.00 26.63  ?  391 TYR A H    1 
ATOM   3849  H HA   . TYR A 1 391 ? 113.543 117.911 107.507 1.00 26.63  ?  391 TYR A HA   1 
ATOM   3850  H HB2  . TYR A 1 391 ? 113.474 120.528 108.565 1.00 26.63  ?  391 TYR A HB2  1 
ATOM   3851  H HB3  . TYR A 1 391 ? 112.734 120.055 107.244 1.00 26.63  ?  391 TYR A HB3  1 
ATOM   3852  H HD1  . TYR A 1 391 ? 111.750 117.492 108.655 1.00 26.63  ?  391 TYR A HD1  1 
ATOM   3853  H HD2  . TYR A 1 391 ? 111.367 121.383 109.497 1.00 26.63  ?  391 TYR A HD2  1 
ATOM   3854  H HE1  . TYR A 1 391 ? 109.854 117.037 109.883 1.00 26.63  ?  391 TYR A HE1  1 
ATOM   3855  H HE2  . TYR A 1 391 ? 109.469 120.930 110.727 1.00 26.63  ?  391 TYR A HE2  1 
ATOM   3856  H HH   . TYR A 1 391 ? 108.039 119.378 111.480 1.00 26.63  ?  391 TYR A HH   1 
ATOM   3857  N N    . GLU A 1 392 ? 116.419 118.754 107.715 1.00 31.39  ?  392 GLU A N    1 
ATOM   3858  C CA   . GLU A 1 392 ? 117.669 119.075 107.022 1.00 31.39  ?  392 GLU A CA   1 
ATOM   3859  C C    . GLU A 1 392 ? 117.879 120.581 106.883 1.00 31.39  ?  392 GLU A C    1 
ATOM   3860  O O    . GLU A 1 392 ? 118.730 121.026 106.106 1.00 31.39  ?  392 GLU A O    1 
ATOM   3861  C CB   . GLU A 1 392 ? 117.728 118.402 105.644 1.00 31.39  ?  392 GLU A CB   1 
ATOM   3862  C CG   . GLU A 1 392 ? 118.300 116.994 105.670 1.00 31.39  ?  392 GLU A CG   1 
ATOM   3863  C CD   . GLU A 1 392 ? 119.808 116.978 105.832 1.00 31.39  ?  392 GLU A CD   1 
ATOM   3864  O OE1  . GLU A 1 392 ? 120.412 118.069 105.912 1.00 31.39  ?  392 GLU A OE1  1 
ATOM   3865  O OE2  . GLU A 1 392 ? 120.390 115.874 105.879 1.00 31.39  -1 392 GLU A OE2  1 
ATOM   3866  H H    . GLU A 1 392 ? 116.543 118.363 108.470 1.00 31.39  ?  392 GLU A H    1 
ATOM   3867  H HA   . GLU A 1 392 ? 118.407 118.726 107.547 1.00 31.39  ?  392 GLU A HA   1 
ATOM   3868  H HB2  . GLU A 1 392 ? 116.836 118.346 105.272 1.00 31.39  ?  392 GLU A HB2  1 
ATOM   3869  H HB3  . GLU A 1 392 ? 118.289 118.935 105.059 1.00 31.39  ?  392 GLU A HB3  1 
ATOM   3870  H HG2  . GLU A 1 392 ? 117.913 116.509 106.416 1.00 31.39  ?  392 GLU A HG2  1 
ATOM   3871  H HG3  . GLU A 1 392 ? 118.083 116.550 104.836 1.00 31.39  ?  392 GLU A HG3  1 
ATOM   3872  N N    . LEU A 1 393 ? 117.120 121.384 107.631 1.00 29.47  ?  393 LEU A N    1 
ATOM   3873  C CA   . LEU A 1 393 ? 117.318 122.830 107.591 1.00 29.47  ?  393 LEU A CA   1 
ATOM   3874  C C    . LEU A 1 393 ? 118.580 123.228 108.348 1.00 29.47  ?  393 LEU A C    1 
ATOM   3875  O O    . LEU A 1 393 ? 119.313 124.128 107.922 1.00 29.47  ?  393 LEU A O    1 
ATOM   3876  C CB   . LEU A 1 393 ? 116.093 123.543 108.165 1.00 29.47  ?  393 LEU A CB   1 
ATOM   3877  C CG   . LEU A 1 393 ? 114.844 123.506 107.281 1.00 29.47  ?  393 LEU A CG   1 
ATOM   3878  C CD1  . LEU A 1 393 ? 113.611 123.910 108.071 1.00 29.47  ?  393 LEU A CD1  1 
ATOM   3879  C CD2  . LEU A 1 393 ? 115.019 124.404 106.065 1.00 29.47  ?  393 LEU A CD2  1 
ATOM   3880  H H    . LEU A 1 393 ? 116.495 121.123 108.160 1.00 29.47  ?  393 LEU A H    1 
ATOM   3881  H HA   . LEU A 1 393 ? 117.424 123.108 106.668 1.00 29.47  ?  393 LEU A HA   1 
ATOM   3882  H HB2  . LEU A 1 393 ? 115.864 123.128 109.011 1.00 29.47  ?  393 LEU A HB2  1 
ATOM   3883  H HB3  . LEU A 1 393 ? 116.320 124.474 108.311 1.00 29.47  ?  393 LEU A HB3  1 
ATOM   3884  H HG   . LEU A 1 393 ? 114.711 122.599 106.964 1.00 29.47  ?  393 LEU A HG   1 
ATOM   3885  H HD11 . LEU A 1 393 ? 113.458 123.256 108.771 1.00 29.47  ?  393 LEU A HD11 1 
ATOM   3886  H HD12 . LEU A 1 393 ? 113.759 124.786 108.461 1.00 29.47  ?  393 LEU A HD12 1 
ATOM   3887  H HD13 . LEU A 1 393 ? 112.848 123.938 107.473 1.00 29.47  ?  393 LEU A HD13 1 
ATOM   3888  H HD21 . LEU A 1 393 ? 115.723 124.044 105.504 1.00 29.47  ?  393 LEU A HD21 1 
ATOM   3889  H HD22 . LEU A 1 393 ? 114.184 124.432 105.572 1.00 29.47  ?  393 LEU A HD22 1 
ATOM   3890  H HD23 . LEU A 1 393 ? 115.256 125.296 106.364 1.00 29.47  ?  393 LEU A HD23 1 
ATOM   3891  N N    . LEU A 1 394 ? 118.848 122.569 109.471 1.00 29.48  ?  394 LEU A N    1 
ATOM   3892  C CA   . LEU A 1 394 ? 120.055 122.829 110.250 1.00 29.48  ?  394 LEU A CA   1 
ATOM   3893  C C    . LEU A 1 394 ? 121.051 121.687 110.086 1.00 29.48  ?  394 LEU A C    1 
ATOM   3894  O O    . LEU A 1 394 ? 120.680 120.569 109.729 1.00 29.48  ?  394 LEU A O    1 
ATOM   3895  C CB   . LEU A 1 394 ? 119.713 123.019 111.729 1.00 29.48  ?  394 LEU A CB   1 
ATOM   3896  C CG   . LEU A 1 394 ? 118.941 124.288 112.096 1.00 29.48  ?  394 LEU A CG   1 
ATOM   3897  C CD1  . LEU A 1 394 ? 118.598 124.289 113.578 1.00 29.48  ?  394 LEU A CD1  1 
ATOM   3898  C CD2  . LEU A 1 394 ? 119.734 125.535 111.731 1.00 29.48  ?  394 LEU A CD2  1 
ATOM   3899  O OXT  . LEU A 1 394 ? 122.250 121.854 110.309 1.00 29.48  -1 394 LEU A OXT  1 
ATOM   3900  H H    . LEU A 1 394 ? 118.341 121.961 109.807 1.00 29.48  ?  394 LEU A H    1 
ATOM   3901  H HA   . LEU A 1 394 ? 120.478 123.640 109.929 1.00 29.48  ?  394 LEU A HA   1 
ATOM   3902  H HB2  . LEU A 1 394 ? 119.177 122.264 112.016 1.00 29.48  ?  394 LEU A HB2  1 
ATOM   3903  H HB3  . LEU A 1 394 ? 120.543 123.032 112.232 1.00 29.48  ?  394 LEU A HB3  1 
ATOM   3904  H HG   . LEU A 1 394 ? 118.110 124.307 111.597 1.00 29.48  ?  394 LEU A HG   1 
ATOM   3905  H HD11 . LEU A 1 394 ? 118.061 123.507 113.777 1.00 29.48  ?  394 LEU A HD11 1 
ATOM   3906  H HD12 . LEU A 1 394 ? 118.101 125.095 113.786 1.00 29.48  ?  394 LEU A HD12 1 
ATOM   3907  H HD13 . LEU A 1 394 ? 119.421 124.265 114.091 1.00 29.48  ?  394 LEU A HD13 1 
ATOM   3908  H HD21 . LEU A 1 394 ? 119.770 125.615 110.765 1.00 29.48  ?  394 LEU A HD21 1 
ATOM   3909  H HD22 . LEU A 1 394 ? 120.631 125.455 112.091 1.00 29.48  ?  394 LEU A HD22 1 
ATOM   3910  H HD23 . LEU A 1 394 ? 119.292 126.311 112.110 1.00 29.48  ?  394 LEU A HD23 1 
ATOM   3911  N N    . GLU B 2 8   ? 147.692 98.437  162.672 1.00 98.45  ?  3   GLU B N    1 
ATOM   3912  C CA   . GLU B 2 8   ? 146.818 97.230  162.619 1.00 98.45  ?  3   GLU B CA   1 
ATOM   3913  C C    . GLU B 2 8   ? 146.211 97.059  161.231 1.00 98.45  ?  3   GLU B C    1 
ATOM   3914  O O    . GLU B 2 8   ? 146.048 95.938  160.749 1.00 98.45  ?  3   GLU B O    1 
ATOM   3915  C CB   . GLU B 2 8   ? 145.709 97.326  163.668 1.00 98.45  ?  3   GLU B CB   1 
ATOM   3916  C CG   . GLU B 2 8   ? 146.211 97.309  165.103 1.00 98.45  ?  3   GLU B CG   1 
ATOM   3917  C CD   . GLU B 2 8   ? 145.180 96.766  166.073 1.00 98.45  ?  3   GLU B CD   1 
ATOM   3918  O OE1  . GLU B 2 8   ? 144.876 95.557  166.005 1.00 98.45  ?  3   GLU B OE1  1 
ATOM   3919  O OE2  . GLU B 2 8   ? 144.674 97.550  166.904 1.00 98.45  -1 3   GLU B OE2  1 
ATOM   3920  H H    . GLU B 2 8   ? 148.336 98.365  162.062 1.00 98.45  ?  3   GLU B H    1 
ATOM   3921  H HA   . GLU B 2 8   ? 147.351 96.444  162.815 1.00 98.45  ?  3   GLU B HA   1 
ATOM   3922  H HB2  . GLU B 2 8   ? 145.224 98.156  163.535 1.00 98.45  ?  3   GLU B HB2  1 
ATOM   3923  H HB3  . GLU B 2 8   ? 145.108 96.573  163.556 1.00 98.45  ?  3   GLU B HB3  1 
ATOM   3924  H HG2  . GLU B 2 8   ? 146.999 96.745  165.155 1.00 98.45  ?  3   GLU B HG2  1 
ATOM   3925  H HG3  . GLU B 2 8   ? 146.431 98.214  165.372 1.00 98.45  ?  3   GLU B HG3  1 
ATOM   3926  N N    . LEU B 2 9   ? 145.877 98.182  160.591 1.00 97.07  ?  4   LEU B N    1 
ATOM   3927  C CA   . LEU B 2 9   ? 145.281 98.121  159.260 1.00 97.07  ?  4   LEU B CA   1 
ATOM   3928  C C    . LEU B 2 9   ? 146.236 97.503  158.248 1.00 97.07  ?  4   LEU B C    1 
ATOM   3929  O O    . LEU B 2 9   ? 145.812 96.707  157.402 1.00 97.07  ?  4   LEU B O    1 
ATOM   3930  C CB   . LEU B 2 9   ? 144.864 99.521  158.808 1.00 97.07  ?  4   LEU B CB   1 
ATOM   3931  C CG   . LEU B 2 9   ? 144.134 99.611  157.466 1.00 97.07  ?  4   LEU B CG   1 
ATOM   3932  C CD1  . LEU B 2 9   ? 142.862 98.775  157.478 1.00 97.07  ?  4   LEU B CD1  1 
ATOM   3933  C CD2  . LEU B 2 9   ? 143.820 101.060 157.127 1.00 97.07  ?  4   LEU B CD2  1 
ATOM   3934  H H    . LEU B 2 9   ? 145.983 98.977  160.901 1.00 97.07  ?  4   LEU B H    1 
ATOM   3935  H HA   . LEU B 2 9   ? 144.487 97.567  159.300 1.00 97.07  ?  4   LEU B HA   1 
ATOM   3936  H HB2  . LEU B 2 9   ? 144.275 99.895  159.482 1.00 97.07  ?  4   LEU B HB2  1 
ATOM   3937  H HB3  . LEU B 2 9   ? 145.662 100.068 158.739 1.00 97.07  ?  4   LEU B HB3  1 
ATOM   3938  H HG   . LEU B 2 9   ? 144.711 99.262  156.769 1.00 97.07  ?  4   LEU B HG   1 
ATOM   3939  H HD11 . LEU B 2 9   ? 143.100 97.836  157.511 1.00 97.07  ?  4   LEU B HD11 1 
ATOM   3940  H HD12 . LEU B 2 9   ? 142.336 99.012  158.259 1.00 97.07  ?  4   LEU B HD12 1 
ATOM   3941  H HD13 . LEU B 2 9   ? 142.356 98.959  156.671 1.00 97.07  ?  4   LEU B HD13 1 
ATOM   3942  H HD21 . LEU B 2 9   ? 144.651 101.558 157.076 1.00 97.07  ?  4   LEU B HD21 1 
ATOM   3943  H HD22 . LEU B 2 9   ? 143.361 101.092 156.273 1.00 97.07  ?  4   LEU B HD22 1 
ATOM   3944  H HD23 . LEU B 2 9   ? 143.254 101.430 157.822 1.00 97.07  ?  4   LEU B HD23 1 
ATOM   3945  N N    . ASP B 2 10  ? 147.522 97.858  158.311 1.00 96.09  ?  5   ASP B N    1 
ATOM   3946  C CA   . ASP B 2 10  ? 148.490 97.275  157.388 1.00 96.09  ?  5   ASP B CA   1 
ATOM   3947  C C    . ASP B 2 10  ? 148.599 95.768  157.587 1.00 96.09  ?  5   ASP B C    1 
ATOM   3948  O O    . ASP B 2 10  ? 148.646 95.007  156.613 1.00 96.09  ?  5   ASP B O    1 
ATOM   3949  C CB   . ASP B 2 10  ? 149.854 97.939  157.571 1.00 96.09  ?  5   ASP B CB   1 
ATOM   3950  C CG   . ASP B 2 10  ? 150.826 97.591  156.460 1.00 96.09  ?  5   ASP B CG   1 
ATOM   3951  O OD1  . ASP B 2 10  ? 150.381 97.054  155.424 1.00 96.09  ?  5   ASP B OD1  1 
ATOM   3952  O OD2  . ASP B 2 10  ? 152.036 97.856  156.622 1.00 96.09  -1 5   ASP B OD2  1 
ATOM   3953  H H    . ASP B 2 10  ? 147.851 98.423  158.869 1.00 96.09  ?  5   ASP B H    1 
ATOM   3954  H HA   . ASP B 2 10  ? 148.195 97.437  156.478 1.00 96.09  ?  5   ASP B HA   1 
ATOM   3955  H HB2  . ASP B 2 10  ? 149.739 98.902  157.580 1.00 96.09  ?  5   ASP B HB2  1 
ATOM   3956  H HB3  . ASP B 2 10  ? 150.239 97.642  158.410 1.00 96.09  ?  5   ASP B HB3  1 
ATOM   3957  N N    . GLN B 2 11  ? 148.641 95.318  158.843 1.00 95.57  ?  6   GLN B N    1 
ATOM   3958  C CA   . GLN B 2 11  ? 148.702 93.885  159.109 1.00 95.57  ?  6   GLN B CA   1 
ATOM   3959  C C    . GLN B 2 11  ? 147.435 93.184  158.638 1.00 95.57  ?  6   GLN B C    1 
ATOM   3960  O O    . GLN B 2 11  ? 147.497 92.071  158.102 1.00 95.57  ?  6   GLN B O    1 
ATOM   3961  C CB   . GLN B 2 11  ? 148.930 93.638  160.600 1.00 95.57  ?  6   GLN B CB   1 
ATOM   3962  C CG   . GLN B 2 11  ? 150.288 94.101  161.099 1.00 95.57  ?  6   GLN B CG   1 
ATOM   3963  C CD   . GLN B 2 11  ? 150.475 93.860  162.583 1.00 95.57  ?  6   GLN B CD   1 
ATOM   3964  O OE1  . GLN B 2 11  ? 149.562 93.402  163.270 1.00 95.57  ?  6   GLN B OE1  1 
ATOM   3965  N NE2  . GLN B 2 11  ? 151.664 94.169  163.087 1.00 95.57  ?  6   GLN B NE2  1 
ATOM   3966  H H    . GLN B 2 11  ? 148.635 95.814  159.545 1.00 95.57  ?  6   GLN B H    1 
ATOM   3967  H HA   . GLN B 2 11  ? 149.452 93.506  158.624 1.00 95.57  ?  6   GLN B HA   1 
ATOM   3968  H HB2  . GLN B 2 11  ? 148.251 94.114  161.102 1.00 95.57  ?  6   GLN B HB2  1 
ATOM   3969  H HB3  . GLN B 2 11  ? 148.860 92.686  160.772 1.00 95.57  ?  6   GLN B HB3  1 
ATOM   3970  H HG2  . GLN B 2 11  ? 150.981 93.616  160.626 1.00 95.57  ?  6   GLN B HG2  1 
ATOM   3971  H HG3  . GLN B 2 11  ? 150.377 95.053  160.935 1.00 95.57  ?  6   GLN B HG3  1 
ATOM   3972  H HE21 . GLN B 2 11  ? 152.278 94.487  162.576 1.00 95.57  ?  6   GLN B HE21 1 
ATOM   3973  H HE22 . GLN B 2 11  ? 151.820 94.050  163.924 1.00 95.57  ?  6   GLN B HE22 1 
ATOM   3974  N N    . LEU B 2 12  ? 146.275 93.814  158.836 1.00 93.11  ?  7   LEU B N    1 
ATOM   3975  C CA   . LEU B 2 12  ? 145.028 93.224  158.360 1.00 93.11  ?  7   LEU B CA   1 
ATOM   3976  C C    . LEU B 2 12  ? 145.033 93.086  156.843 1.00 93.11  ?  7   LEU B C    1 
ATOM   3977  O O    . LEU B 2 12  ? 144.624 92.051  156.303 1.00 93.11  ?  7   LEU B O    1 
ATOM   3978  C CB   . LEU B 2 12  ? 143.842 94.074  158.816 1.00 93.11  ?  7   LEU B CB   1 
ATOM   3979  C CG   . LEU B 2 12  ? 143.337 93.815  160.236 1.00 93.11  ?  7   LEU B CG   1 
ATOM   3980  C CD1  . LEU B 2 12  ? 142.461 94.966  160.704 1.00 93.11  ?  7   LEU B CD1  1 
ATOM   3981  C CD2  . LEU B 2 12  ? 142.577 92.499  160.309 1.00 93.11  ?  7   LEU B CD2  1 
ATOM   3982  H H    . LEU B 2 12  ? 146.186 94.570  159.236 1.00 93.11  ?  7   LEU B H    1 
ATOM   3983  H HA   . LEU B 2 12  ? 144.930 92.338  158.742 1.00 93.11  ?  7   LEU B HA   1 
ATOM   3984  H HB2  . LEU B 2 12  ? 144.098 95.008  158.766 1.00 93.11  ?  7   LEU B HB2  1 
ATOM   3985  H HB3  . LEU B 2 12  ? 143.100 93.910  158.212 1.00 93.11  ?  7   LEU B HB3  1 
ATOM   3986  H HG   . LEU B 2 12  ? 144.097 93.754  160.835 1.00 93.11  ?  7   LEU B HG   1 
ATOM   3987  H HD11 . LEU B 2 12  ? 142.985 95.782  160.698 1.00 93.11  ?  7   LEU B HD11 1 
ATOM   3988  H HD12 . LEU B 2 12  ? 141.707 95.053  160.100 1.00 93.11  ?  7   LEU B HD12 1 
ATOM   3989  H HD13 . LEU B 2 12  ? 142.147 94.779  161.602 1.00 93.11  ?  7   LEU B HD13 1 
ATOM   3990  H HD21 . LEU B 2 12  ? 143.182 91.771  160.098 1.00 93.11  ?  7   LEU B HD21 1 
ATOM   3991  H HD22 . LEU B 2 12  ? 141.848 92.520  159.670 1.00 93.11  ?  7   LEU B HD22 1 
ATOM   3992  H HD23 . LEU B 2 12  ? 142.227 92.387  161.207 1.00 93.11  ?  7   LEU B HD23 1 
ATOM   3993  N N    . ARG B 2 13  ? 145.494 94.122  156.137 1.00 85.89  ?  8   ARG B N    1 
ATOM   3994  C CA   . ARG B 2 13  ? 145.557 94.051  154.681 1.00 85.89  ?  8   ARG B CA   1 
ATOM   3995  C C    . ARG B 2 13  ? 146.543 92.984  154.226 1.00 85.89  ?  8   ARG B C    1 
ATOM   3996  O O    . ARG B 2 13  ? 146.288 92.267  153.252 1.00 85.89  ?  8   ARG B O    1 
ATOM   3997  C CB   . ARG B 2 13  ? 145.938 95.412  154.102 1.00 85.89  ?  8   ARG B CB   1 
ATOM   3998  C CG   . ARG B 2 13  ? 145.941 95.449  152.582 1.00 85.89  ?  8   ARG B CG   1 
ATOM   3999  C CD   . ARG B 2 13  ? 145.904 96.873  152.055 1.00 85.89  ?  8   ARG B CD   1 
ATOM   4000  N NE   . ARG B 2 13  ? 147.161 97.579  152.293 1.00 85.89  ?  8   ARG B NE   1 
ATOM   4001  C CZ   . ARG B 2 13  ? 148.218 97.530  151.487 1.00 85.89  ?  8   ARG B CZ   1 
ATOM   4002  N NH1  . ARG B 2 13  ? 149.314 98.210  151.794 1.00 85.89  1  8   ARG B NH1  1 
ATOM   4003  N NH2  . ARG B 2 13  ? 148.186 96.805  150.376 1.00 85.89  ?  8   ARG B NH2  1 
ATOM   4004  H H    . ARG B 2 13  ? 145.772 94.863  156.473 1.00 85.89  ?  8   ARG B H    1 
ATOM   4005  H HA   . ARG B 2 13  ? 144.680 93.814  154.339 1.00 85.89  ?  8   ARG B HA   1 
ATOM   4006  H HB2  . ARG B 2 13  ? 145.302 96.074  154.415 1.00 85.89  ?  8   ARG B HB2  1 
ATOM   4007  H HB3  . ARG B 2 13  ? 146.830 95.643  154.406 1.00 85.89  ?  8   ARG B HB3  1 
ATOM   4008  H HG2  . ARG B 2 13  ? 146.749 95.024  152.254 1.00 85.89  ?  8   ARG B HG2  1 
ATOM   4009  H HG3  . ARG B 2 13  ? 145.158 94.981  152.249 1.00 85.89  ?  8   ARG B HG3  1 
ATOM   4010  H HD2  . ARG B 2 13  ? 145.734 96.857  151.101 1.00 85.89  ?  8   ARG B HD2  1 
ATOM   4011  H HD3  . ARG B 2 13  ? 145.198 97.359  152.508 1.00 85.89  ?  8   ARG B HD3  1 
ATOM   4012  H HE   . ARG B 2 13  ? 147.212 98.080  152.991 1.00 85.89  ?  8   ARG B HE   1 
ATOM   4013  H HH11 . ARG B 2 13  ? 149.341 98.681  152.513 1.00 85.89  ?  8   ARG B HH11 1 
ATOM   4014  H HH12 . ARG B 2 13  ? 149.999 98.179  151.275 1.00 85.89  ?  8   ARG B HH12 1 
ATOM   4015  H HH21 . ARG B 2 13  ? 147.481 96.360  150.167 1.00 85.89  ?  8   ARG B HH21 1 
ATOM   4016  H HH22 . ARG B 2 13  ? 148.875 96.780  149.862 1.00 85.89  ?  8   ARG B HH22 1 
ATOM   4017  N N    . GLN B 2 14  ? 147.683 92.870  154.912 1.00 89.71  ?  9   GLN B N    1 
ATOM   4018  C CA   . GLN B 2 14  ? 148.652 91.837  154.561 1.00 89.71  ?  9   GLN B CA   1 
ATOM   4019  C C    . GLN B 2 14  ? 148.066 90.445  154.763 1.00 89.71  ?  9   GLN B C    1 
ATOM   4020  O O    . GLN B 2 14  ? 148.255 89.556  153.925 1.00 89.71  ?  9   GLN B O    1 
ATOM   4021  C CB   . GLN B 2 14  ? 149.925 92.009  155.389 1.00 89.71  ?  9   GLN B CB   1 
ATOM   4022  C CG   . GLN B 2 14  ? 150.998 92.841  154.705 1.00 89.71  ?  9   GLN B CG   1 
ATOM   4023  C CD   . GLN B 2 14  ? 151.627 92.127  153.525 1.00 89.71  ?  9   GLN B CD   1 
ATOM   4024  O OE1  . GLN B 2 14  ? 151.653 90.897  153.471 1.00 89.71  ?  9   GLN B OE1  1 
ATOM   4025  N NE2  . GLN B 2 14  ? 152.139 92.897  152.572 1.00 89.71  ?  9   GLN B NE2  1 
ATOM   4026  H H    . GLN B 2 14  ? 147.915 93.373  155.570 1.00 89.71  ?  9   GLN B H    1 
ATOM   4027  H HA   . GLN B 2 14  ? 148.886 91.930  153.624 1.00 89.71  ?  9   GLN B HA   1 
ATOM   4028  H HB2  . GLN B 2 14  ? 149.699 92.448  156.224 1.00 89.71  ?  9   GLN B HB2  1 
ATOM   4029  H HB3  . GLN B 2 14  ? 150.300 91.134  155.570 1.00 89.71  ?  9   GLN B HB3  1 
ATOM   4030  H HG2  . GLN B 2 14  ? 150.601 93.665  154.381 1.00 89.71  ?  9   GLN B HG2  1 
ATOM   4031  H HG3  . GLN B 2 14  ? 151.700 93.041  155.345 1.00 89.71  ?  9   GLN B HG3  1 
ATOM   4032  H HE21 . GLN B 2 14  ? 152.102 93.753  152.644 1.00 89.71  ?  9   GLN B HE21 1 
ATOM   4033  H HE22 . GLN B 2 14  ? 152.507 92.539  151.881 1.00 89.71  ?  9   GLN B HE22 1 
ATOM   4034  N N    . GLU B 2 15  ? 147.352 90.237  155.872 1.00 88.50  ?  10  GLU B N    1 
ATOM   4035  C CA   . GLU B 2 15  ? 146.718 88.944  156.107 1.00 88.50  ?  10  GLU B CA   1 
ATOM   4036  C C    . GLU B 2 15  ? 145.671 88.650  155.041 1.00 88.50  ?  10  GLU B C    1 
ATOM   4037  O O    . GLU B 2 15  ? 145.577 87.520  154.545 1.00 88.50  ?  10  GLU B O    1 
ATOM   4038  C CB   . GLU B 2 15  ? 146.088 88.913  157.501 1.00 88.50  ?  10  GLU B CB   1 
ATOM   4039  C CG   . GLU B 2 15  ? 145.609 87.532  157.927 1.00 88.50  ?  10  GLU B CG   1 
ATOM   4040  C CD   . GLU B 2 15  ? 144.979 87.527  159.307 1.00 88.50  ?  10  GLU B CD   1 
ATOM   4041  O OE1  . GLU B 2 15  ? 145.076 88.553  160.013 1.00 88.50  ?  10  GLU B OE1  1 
ATOM   4042  O OE2  . GLU B 2 15  ? 144.387 86.494  159.686 1.00 88.50  -1 10  GLU B OE2  1 
ATOM   4043  H H    . GLU B 2 15  ? 147.221 90.819  156.491 1.00 88.50  ?  10  GLU B H    1 
ATOM   4044  H HA   . GLU B 2 15  ? 147.392 88.248  156.067 1.00 88.50  ?  10  GLU B HA   1 
ATOM   4045  H HB2  . GLU B 2 15  ? 146.746 89.211  158.148 1.00 88.50  ?  10  GLU B HB2  1 
ATOM   4046  H HB3  . GLU B 2 15  ? 145.323 89.509  157.513 1.00 88.50  ?  10  GLU B HB3  1 
ATOM   4047  H HG2  . GLU B 2 15  ? 144.943 87.220  157.294 1.00 88.50  ?  10  GLU B HG2  1 
ATOM   4048  H HG3  . GLU B 2 15  ? 146.365 86.926  157.940 1.00 88.50  ?  10  GLU B HG3  1 
ATOM   4049  N N    . ALA B 2 16  ? 144.871 89.655  154.678 1.00 85.28  ?  11  ALA B N    1 
ATOM   4050  C CA   . ALA B 2 16  ? 143.864 89.458  153.642 1.00 85.28  ?  11  ALA B CA   1 
ATOM   4051  C C    . ALA B 2 16  ? 144.511 89.102  152.311 1.00 85.28  ?  11  ALA B C    1 
ATOM   4052  O O    . ALA B 2 16  ? 144.035 88.210  151.601 1.00 85.28  ?  11  ALA B O    1 
ATOM   4053  C CB   . ALA B 2 16  ? 143.001 90.712  153.503 1.00 85.28  ?  11  ALA B CB   1 
ATOM   4054  H H    . ALA B 2 16  ? 144.895 90.449  155.009 1.00 85.28  ?  11  ALA B H    1 
ATOM   4055  H HA   . ALA B 2 16  ? 143.286 88.723  153.900 1.00 85.28  ?  11  ALA B HA   1 
ATOM   4056  H HB1  . ALA B 2 16  ? 142.337 90.561  152.812 1.00 85.28  ?  11  ALA B HB1  1 
ATOM   4057  H HB2  . ALA B 2 16  ? 143.567 91.461  153.260 1.00 85.28  ?  11  ALA B HB2  1 
ATOM   4058  H HB3  . ALA B 2 16  ? 142.562 90.889  154.350 1.00 85.28  ?  11  ALA B HB3  1 
ATOM   4059  N N    . GLU B 2 17  ? 145.599 89.788  151.954 1.00 83.31  ?  12  GLU B N    1 
ATOM   4060  C CA   . GLU B 2 17  ? 146.286 89.486  150.703 1.00 83.31  ?  12  GLU B CA   1 
ATOM   4061  C C    . GLU B 2 17  ? 146.878 88.082  150.726 1.00 83.31  ?  12  GLU B C    1 
ATOM   4062  O O    . GLU B 2 17  ? 146.796 87.351  149.732 1.00 83.31  ?  12  GLU B O    1 
ATOM   4063  C CB   . GLU B 2 17  ? 147.376 90.527  150.440 1.00 83.31  ?  12  GLU B CB   1 
ATOM   4064  C CG   . GLU B 2 17  ? 147.969 90.467  149.038 1.00 83.31  ?  12  GLU B CG   1 
ATOM   4065  C CD   . GLU B 2 17  ? 148.347 91.836  148.505 1.00 83.31  ?  12  GLU B CD   1 
ATOM   4066  O OE1  . GLU B 2 17  ? 149.035 92.588  149.226 1.00 83.31  ?  12  GLU B OE1  1 
ATOM   4067  O OE2  . GLU B 2 17  ? 147.955 92.160  147.364 1.00 83.31  -1 12  GLU B OE2  1 
ATOM   4068  H H    . GLU B 2 17  ? 145.951 90.425  152.412 1.00 83.31  ?  12  GLU B H    1 
ATOM   4069  H HA   . GLU B 2 17  ? 145.648 89.529  149.975 1.00 83.31  ?  12  GLU B HA   1 
ATOM   4070  H HB2  . GLU B 2 17  ? 146.998 91.411  150.563 1.00 83.31  ?  12  GLU B HB2  1 
ATOM   4071  H HB3  . GLU B 2 17  ? 148.098 90.387  151.071 1.00 83.31  ?  12  GLU B HB3  1 
ATOM   4072  H HG2  . GLU B 2 17  ? 148.769 89.919  149.054 1.00 83.31  ?  12  GLU B HG2  1 
ATOM   4073  H HG3  . GLU B 2 17  ? 147.314 90.082  148.434 1.00 83.31  ?  12  GLU B HG3  1 
ATOM   4074  N N    . GLN B 2 18  ? 147.473 87.682  151.854 1.00 83.95  ?  13  GLN B N    1 
ATOM   4075  C CA   . GLN B 2 18  ? 148.045 86.342  151.945 1.00 83.95  ?  13  GLN B CA   1 
ATOM   4076  C C    . GLN B 2 18  ? 146.964 85.276  151.818 1.00 83.95  ?  13  GLN B C    1 
ATOM   4077  O O    . GLN B 2 18  ? 147.157 84.261  151.139 1.00 83.95  ?  13  GLN B O    1 
ATOM   4078  C CB   . GLN B 2 18  ? 148.804 86.182  153.264 1.00 83.95  ?  13  GLN B CB   1 
ATOM   4079  C CG   . GLN B 2 18  ? 149.296 84.763  153.531 1.00 83.95  ?  13  GLN B CG   1 
ATOM   4080  C CD   . GLN B 2 18  ? 148.354 83.971  154.421 1.00 83.95  ?  13  GLN B CD   1 
ATOM   4081  O OE1  . GLN B 2 18  ? 147.806 84.499  155.389 1.00 83.95  ?  13  GLN B OE1  1 
ATOM   4082  N NE2  . GLN B 2 18  ? 148.159 82.699  154.093 1.00 83.95  ?  13  GLN B NE2  1 
ATOM   4083  H H    . GLN B 2 18  ? 147.547 88.154  152.568 1.00 83.95  ?  13  GLN B H    1 
ATOM   4084  H HA   . GLN B 2 18  ? 148.677 86.220  151.221 1.00 83.95  ?  13  GLN B HA   1 
ATOM   4085  H HB2  . GLN B 2 18  ? 149.577 86.767  153.252 1.00 83.95  ?  13  GLN B HB2  1 
ATOM   4086  H HB3  . GLN B 2 18  ? 148.214 86.433  153.993 1.00 83.95  ?  13  GLN B HB3  1 
ATOM   4087  H HG2  . GLN B 2 18  ? 149.373 84.294  152.687 1.00 83.95  ?  13  GLN B HG2  1 
ATOM   4088  H HG3  . GLN B 2 18  ? 150.162 84.804  153.967 1.00 83.95  ?  13  GLN B HG3  1 
ATOM   4089  H HE21 . GLN B 2 18  ? 148.557 82.364  153.409 1.00 83.95  ?  13  GLN B HE21 1 
ATOM   4090  H HE22 . GLN B 2 18  ? 147.633 82.211  154.567 1.00 83.95  ?  13  GLN B HE22 1 
ATOM   4091  N N    . LEU B 2 19  ? 145.816 85.489  152.459 1.00 80.26  ?  14  LEU B N    1 
ATOM   4092  C CA   . LEU B 2 19  ? 144.760 84.487  152.397 1.00 80.26  ?  14  LEU B CA   1 
ATOM   4093  C C    . LEU B 2 19  ? 144.100 84.473  151.022 1.00 80.26  ?  14  LEU B C    1 
ATOM   4094  O O    . LEU B 2 19  ? 143.665 83.418  150.548 1.00 80.26  ?  14  LEU B O    1 
ATOM   4095  C CB   . LEU B 2 19  ? 143.750 84.732  153.519 1.00 80.26  ?  14  LEU B CB   1 
ATOM   4096  C CG   . LEU B 2 19  ? 142.460 83.913  153.519 1.00 80.26  ?  14  LEU B CG   1 
ATOM   4097  C CD1  . LEU B 2 19  ? 142.735 82.563  154.153 1.00 80.26  ?  14  LEU B CD1  1 
ATOM   4098  C CD2  . LEU B 2 19  ? 141.382 84.623  154.312 1.00 80.26  ?  14  LEU B CD2  1 
ATOM   4099  H H    . LEU B 2 19  ? 145.630 86.188  152.926 1.00 80.26  ?  14  LEU B H    1 
ATOM   4100  H HA   . LEU B 2 19  ? 145.148 83.610  152.540 1.00 80.26  ?  14  LEU B HA   1 
ATOM   4101  H HB2  . LEU B 2 19  ? 144.191 84.553  154.363 1.00 80.26  ?  14  LEU B HB2  1 
ATOM   4102  H HB3  . LEU B 2 19  ? 143.492 85.667  153.485 1.00 80.26  ?  14  LEU B HB3  1 
ATOM   4103  H HG   . LEU B 2 19  ? 142.144 83.779  152.611 1.00 80.26  ?  14  LEU B HG   1 
ATOM   4104  H HD11 . LEU B 2 19  ? 143.397 82.102  153.618 1.00 80.26  ?  14  LEU B HD11 1 
ATOM   4105  H HD12 . LEU B 2 19  ? 141.912 82.050  154.180 1.00 80.26  ?  14  LEU B HD12 1 
ATOM   4106  H HD13 . LEU B 2 19  ? 143.072 82.703  155.052 1.00 80.26  ?  14  LEU B HD13 1 
ATOM   4107  H HD21 . LEU B 2 19  ? 141.645 84.653  155.245 1.00 80.26  ?  14  LEU B HD21 1 
ATOM   4108  H HD22 . LEU B 2 19  ? 140.554 84.132  154.219 1.00 80.26  ?  14  LEU B HD22 1 
ATOM   4109  H HD23 . LEU B 2 19  ? 141.278 85.522  153.972 1.00 80.26  ?  14  LEU B HD23 1 
ATOM   4110  N N    . LYS B 2 20  ? 144.042 85.624  150.347 1.00 79.38  ?  15  LYS B N    1 
ATOM   4111  C CA   . LYS B 2 20  ? 143.575 85.633  148.965 1.00 79.38  ?  15  LYS B CA   1 
ATOM   4112  C C    . LYS B 2 20  ? 144.538 84.870  148.066 1.00 79.38  ?  15  LYS B C    1 
ATOM   4113  O O    . LYS B 2 20  ? 144.116 84.166  147.141 1.00 79.38  ?  15  LYS B O    1 
ATOM   4114  C CB   . LYS B 2 20  ? 143.414 87.067  148.464 1.00 79.38  ?  15  LYS B CB   1 
ATOM   4115  C CG   . LYS B 2 20  ? 142.110 87.719  148.877 1.00 79.38  ?  15  LYS B CG   1 
ATOM   4116  C CD   . LYS B 2 20  ? 141.966 89.106  148.280 1.00 79.38  ?  15  LYS B CD   1 
ATOM   4117  C CE   . LYS B 2 20  ? 142.893 90.101  148.949 1.00 79.38  ?  15  LYS B CE   1 
ATOM   4118  N NZ   . LYS B 2 20  ? 142.676 91.481  148.444 1.00 79.38  1  15  LYS B NZ   1 
ATOM   4119  H H    . LYS B 2 20  ? 144.261 86.395  150.660 1.00 79.38  ?  15  LYS B H    1 
ATOM   4120  H HA   . LYS B 2 20  ? 142.708 85.201  148.919 1.00 79.38  ?  15  LYS B HA   1 
ATOM   4121  H HB2  . LYS B 2 20  ? 144.144 87.604  148.811 1.00 79.38  ?  15  LYS B HB2  1 
ATOM   4122  H HB3  . LYS B 2 20  ? 143.445 87.059  147.494 1.00 79.38  ?  15  LYS B HB3  1 
ATOM   4123  H HG2  . LYS B 2 20  ? 141.364 87.172  148.586 1.00 79.38  ?  15  LYS B HG2  1 
ATOM   4124  H HG3  . LYS B 2 20  ? 142.105 87.815  149.840 1.00 79.38  ?  15  LYS B HG3  1 
ATOM   4125  H HD2  . LYS B 2 20  ? 142.182 89.072  147.335 1.00 79.38  ?  15  LYS B HD2  1 
ATOM   4126  H HD3  . LYS B 2 20  ? 141.054 89.412  148.405 1.00 79.38  ?  15  LYS B HD3  1 
ATOM   4127  H HE2  . LYS B 2 20  ? 142.738 90.095  149.906 1.00 79.38  ?  15  LYS B HE2  1 
ATOM   4128  H HE3  . LYS B 2 20  ? 143.809 89.854  148.754 1.00 79.38  ?  15  LYS B HE3  1 
ATOM   4129  H HZ1  . LYS B 2 20  ? 143.213 92.049  148.871 1.00 79.38  ?  15  LYS B HZ1  1 
ATOM   4130  H HZ2  . LYS B 2 20  ? 141.831 91.722  148.582 1.00 79.38  ?  15  LYS B HZ2  1 
ATOM   4131  H HZ3  . LYS B 2 20  ? 142.850 91.518  147.572 1.00 79.38  ?  15  LYS B HZ3  1 
ATOM   4132  N N    . ASN B 2 21  ? 145.842 85.008  148.316 1.00 79.02  ?  16  ASN B N    1 
ATOM   4133  C CA   . ASN B 2 21  ? 146.826 84.234  147.566 1.00 79.02  ?  16  ASN B CA   1 
ATOM   4134  C C    . ASN B 2 21  ? 146.651 82.742  147.818 1.00 79.02  ?  16  ASN B C    1 
ATOM   4135  O O    . ASN B 2 21  ? 146.779 81.927  146.898 1.00 79.02  ?  16  ASN B O    1 
ATOM   4136  C CB   . ASN B 2 21  ? 148.240 84.678  147.946 1.00 79.02  ?  16  ASN B CB   1 
ATOM   4137  C CG   . ASN B 2 21  ? 148.840 85.650  146.945 1.00 79.02  ?  16  ASN B CG   1 
ATOM   4138  O OD1  . ASN B 2 21  ? 148.446 85.690  145.780 1.00 79.02  ?  16  ASN B OD1  1 
ATOM   4139  N ND2  . ASN B 2 21  ? 149.800 86.446  147.403 1.00 79.02  ?  16  ASN B ND2  1 
ATOM   4140  H H    . ASN B 2 21  ? 146.175 85.538  148.906 1.00 79.02  ?  16  ASN B H    1 
ATOM   4141  H HA   . ASN B 2 21  ? 146.696 84.393  146.619 1.00 79.02  ?  16  ASN B HA   1 
ATOM   4142  H HB2  . ASN B 2 21  ? 148.215 85.117  148.810 1.00 79.02  ?  16  ASN B HB2  1 
ATOM   4143  H HB3  . ASN B 2 21  ? 148.815 83.898  147.986 1.00 79.02  ?  16  ASN B HB3  1 
ATOM   4144  H HD21 . ASN B 2 21  ? 150.047 86.390  148.225 1.00 79.02  ?  16  ASN B HD21 1 
ATOM   4145  H HD22 . ASN B 2 21  ? 150.174 87.017  146.879 1.00 79.02  ?  16  ASN B HD22 1 
ATOM   4146  N N    . GLN B 2 22  ? 146.372 82.366  149.068 1.00 77.45  ?  17  GLN B N    1 
ATOM   4147  C CA   . GLN B 2 22  ? 146.089 80.965  149.373 1.00 77.45  ?  17  GLN B CA   1 
ATOM   4148  C C    . GLN B 2 22  ? 144.854 80.487  148.618 1.00 77.45  ?  17  GLN B C    1 
ATOM   4149  O O    . GLN B 2 22  ? 144.829 79.364  148.097 1.00 77.45  ?  17  GLN B O    1 
ATOM   4150  C CB   . GLN B 2 22  ? 145.911 80.787  150.883 1.00 77.45  ?  17  GLN B CB   1 
ATOM   4151  C CG   . GLN B 2 22  ? 146.160 79.368  151.398 1.00 77.45  ?  17  GLN B CG   1 
ATOM   4152  C CD   . GLN B 2 22  ? 145.019 78.403  151.115 1.00 77.45  ?  17  GLN B CD   1 
ATOM   4153  O OE1  . GLN B 2 22  ? 144.001 78.770  150.530 1.00 77.45  ?  17  GLN B OE1  1 
ATOM   4154  N NE2  . GLN B 2 22  ? 145.190 77.155  151.534 1.00 77.45  ?  17  GLN B NE2  1 
ATOM   4155  H H    . GLN B 2 22  ? 146.343 82.893  149.746 1.00 77.45  ?  17  GLN B H    1 
ATOM   4156  H HA   . GLN B 2 22  ? 146.842 80.422  149.093 1.00 77.45  ?  17  GLN B HA   1 
ATOM   4157  H HB2  . GLN B 2 22  ? 146.533 81.376  151.339 1.00 77.45  ?  17  GLN B HB2  1 
ATOM   4158  H HB3  . GLN B 2 22  ? 145.002 81.030  151.119 1.00 77.45  ?  17  GLN B HB3  1 
ATOM   4159  H HG2  . GLN B 2 22  ? 146.956 79.016  150.971 1.00 77.45  ?  17  GLN B HG2  1 
ATOM   4160  H HG3  . GLN B 2 22  ? 146.289 79.400  152.359 1.00 77.45  ?  17  GLN B HG3  1 
ATOM   4161  H HE21 . GLN B 2 22  ? 145.915 76.934  151.940 1.00 77.45  ?  17  GLN B HE21 1 
ATOM   4162  H HE22 . GLN B 2 22  ? 144.576 76.567  151.400 1.00 77.45  ?  17  GLN B HE22 1 
ATOM   4163  N N    . ILE B 2 23  ? 143.818 81.325  148.552 1.00 74.65  ?  18  ILE B N    1 
ATOM   4164  C CA   . ILE B 2 23  ? 142.617 80.976  147.797 1.00 74.65  ?  18  ILE B CA   1 
ATOM   4165  C C    . ILE B 2 23  ? 142.963 80.756  146.330 1.00 74.65  ?  18  ILE B C    1 
ATOM   4166  O O    . ILE B 2 23  ? 142.513 79.791  145.702 1.00 74.65  ?  18  ILE B O    1 
ATOM   4167  C CB   . ILE B 2 23  ? 141.545 82.069  147.958 1.00 74.65  ?  18  ILE B CB   1 
ATOM   4168  C CG1  . ILE B 2 23  ? 140.955 82.038  149.369 1.00 74.65  ?  18  ILE B CG1  1 
ATOM   4169  C CG2  . ILE B 2 23  ? 140.454 81.908  146.907 1.00 74.65  ?  18  ILE B CG2  1 
ATOM   4170  C CD1  . ILE B 2 23  ? 139.925 80.952  149.574 1.00 74.65  ?  18  ILE B CD1  1 
ATOM   4171  H H    . ILE B 2 23  ? 143.787 82.096  148.933 1.00 74.65  ?  18  ILE B H    1 
ATOM   4172  H HA   . ILE B 2 23  ? 142.256 80.146  148.146 1.00 74.65  ?  18  ILE B HA   1 
ATOM   4173  H HB   . ILE B 2 23  ? 141.969 82.932  147.826 1.00 74.65  ?  18  ILE B HB   1 
ATOM   4174  H HG12 . ILE B 2 23  ? 141.672 81.895  150.007 1.00 74.65  ?  18  ILE B HG12 1 
ATOM   4175  H HG13 . ILE B 2 23  ? 140.524 82.889  149.544 1.00 74.65  ?  18  ILE B HG13 1 
ATOM   4176  H HG21 . ILE B 2 23  ? 140.770 82.264  146.062 1.00 74.65  ?  18  ILE B HG21 1 
ATOM   4177  H HG22 . ILE B 2 23  ? 139.667 82.397  147.194 1.00 74.65  ?  18  ILE B HG22 1 
ATOM   4178  H HG23 . ILE B 2 23  ? 140.240 80.967  146.813 1.00 74.65  ?  18  ILE B HG23 1 
ATOM   4179  H HD11 . ILE B 2 23  ? 139.749 80.869  150.521 1.00 74.65  ?  18  ILE B HD11 1 
ATOM   4180  H HD12 . ILE B 2 23  ? 140.274 80.116  149.227 1.00 74.65  ?  18  ILE B HD12 1 
ATOM   4181  H HD13 . ILE B 2 23  ? 139.110 81.190  149.106 1.00 74.65  ?  18  ILE B HD13 1 
ATOM   4182  N N    . ARG B 2 24  ? 143.761 81.660  145.761 1.00 74.62  ?  19  ARG B N    1 
ATOM   4183  C CA   . ARG B 2 24  ? 144.148 81.531  144.361 1.00 74.62  ?  19  ARG B CA   1 
ATOM   4184  C C    . ARG B 2 24  ? 144.928 80.244  144.128 1.00 74.62  ?  19  ARG B C    1 
ATOM   4185  O O    . ARG B 2 24  ? 144.694 79.535  143.142 1.00 74.62  ?  19  ARG B O    1 
ATOM   4186  C CB   . ARG B 2 24  ? 144.978 82.744  143.936 1.00 74.62  ?  19  ARG B CB   1 
ATOM   4187  C CG   . ARG B 2 24  ? 145.310 82.794  142.450 1.00 74.62  ?  19  ARG B CG   1 
ATOM   4188  C CD   . ARG B 2 24  ? 146.644 83.483  142.203 1.00 74.62  ?  19  ARG B CD   1 
ATOM   4189  N NE   . ARG B 2 24  ? 146.676 84.841  142.740 1.00 74.62  ?  19  ARG B NE   1 
ATOM   4190  C CZ   . ARG B 2 24  ? 147.555 85.772  142.377 1.00 74.62  ?  19  ARG B CZ   1 
ATOM   4191  N NH1  . ARG B 2 24  ? 147.502 86.980  142.922 1.00 74.62  1  19  ARG B NH1  1 
ATOM   4192  N NH2  . ARG B 2 24  ? 148.489 85.499  141.476 1.00 74.62  ?  19  ARG B NH2  1 
ATOM   4193  H H    . ARG B 2 24  ? 144.087 82.349  146.160 1.00 74.62  ?  19  ARG B H    1 
ATOM   4194  H HA   . ARG B 2 24  ? 143.349 81.504  143.812 1.00 74.62  ?  19  ARG B HA   1 
ATOM   4195  H HB2  . ARG B 2 24  ? 144.483 83.550  144.153 1.00 74.62  ?  19  ARG B HB2  1 
ATOM   4196  H HB3  . ARG B 2 24  ? 145.815 82.734  144.424 1.00 74.62  ?  19  ARG B HB3  1 
ATOM   4197  H HG2  . ARG B 2 24  ? 145.363 81.894  142.095 1.00 74.62  ?  19  ARG B HG2  1 
ATOM   4198  H HG3  . ARG B 2 24  ? 144.621 83.296  141.986 1.00 74.62  ?  19  ARG B HG3  1 
ATOM   4199  H HD2  . ARG B 2 24  ? 147.350 82.972  142.630 1.00 74.62  ?  19  ARG B HD2  1 
ATOM   4200  H HD3  . ARG B 2 24  ? 146.800 83.532  141.247 1.00 74.62  ?  19  ARG B HD3  1 
ATOM   4201  H HE   . ARG B 2 24  ? 146.075 85.060  143.314 1.00 74.62  ?  19  ARG B HE   1 
ATOM   4202  H HH11 . ARG B 2 24  ? 146.899 87.162  143.507 1.00 74.62  ?  19  ARG B HH11 1 
ATOM   4203  H HH12 . ARG B 2 24  ? 148.071 87.581  142.689 1.00 74.62  ?  19  ARG B HH12 1 
ATOM   4204  H HH21 . ARG B 2 24  ? 148.532 84.719  141.117 1.00 74.62  ?  19  ARG B HH21 1 
ATOM   4205  H HH22 . ARG B 2 24  ? 149.054 86.106  141.248 1.00 74.62  ?  19  ARG B HH22 1 
ATOM   4206  N N    . ASP B 2 25  ? 145.860 79.925  145.029 1.00 74.59  ?  20  ASP B N    1 
ATOM   4207  C CA   . ASP B 2 25  ? 146.641 78.701  144.884 1.00 74.59  ?  20  ASP B CA   1 
ATOM   4208  C C    . ASP B 2 25  ? 145.748 77.470  144.955 1.00 74.59  ?  20  ASP B C    1 
ATOM   4209  O O    . ASP B 2 25  ? 145.912 76.528  144.172 1.00 74.59  ?  20  ASP B O    1 
ATOM   4210  C CB   . ASP B 2 25  ? 147.723 78.639  145.962 1.00 74.59  ?  20  ASP B CB   1 
ATOM   4211  C CG   . ASP B 2 25  ? 148.768 79.726  145.802 1.00 74.59  ?  20  ASP B CG   1 
ATOM   4212  O OD1  . ASP B 2 25  ? 148.813 80.357  144.725 1.00 74.59  ?  20  ASP B OD1  1 
ATOM   4213  O OD2  . ASP B 2 25  ? 149.547 79.947  146.753 1.00 74.59  -1 20  ASP B OD2  1 
ATOM   4214  H H    . ASP B 2 25  ? 146.054 80.394  145.723 1.00 74.59  ?  20  ASP B H    1 
ATOM   4215  H HA   . ASP B 2 25  ? 147.077 78.706  144.018 1.00 74.59  ?  20  ASP B HA   1 
ATOM   4216  H HB2  . ASP B 2 25  ? 147.309 78.745  146.833 1.00 74.59  ?  20  ASP B HB2  1 
ATOM   4217  H HB3  . ASP B 2 25  ? 148.172 77.781  145.909 1.00 74.59  ?  20  ASP B HB3  1 
ATOM   4218  N N    . ALA B 2 26  ? 144.796 77.457  145.892 1.00 70.75  ?  21  ALA B N    1 
ATOM   4219  C CA   . ALA B 2 26  ? 143.879 76.326  145.990 1.00 70.75  ?  21  ALA B CA   1 
ATOM   4220  C C    . ALA B 2 26  ? 143.039 76.191  144.727 1.00 70.75  ?  21  ALA B C    1 
ATOM   4221  O O    . ALA B 2 26  ? 142.839 75.082  144.219 1.00 70.75  ?  21  ALA B O    1 
ATOM   4222  C CB   . ALA B 2 26  ? 142.981 76.483  147.217 1.00 70.75  ?  21  ALA B CB   1 
ATOM   4223  H H    . ALA B 2 26  ? 144.664 78.079  146.471 1.00 70.75  ?  21  ALA B H    1 
ATOM   4224  H HA   . ALA B 2 26  ? 144.393 75.511  146.096 1.00 70.75  ?  21  ALA B HA   1 
ATOM   4225  H HB1  . ALA B 2 26  ? 142.382 75.722  147.267 1.00 70.75  ?  21  ALA B HB1  1 
ATOM   4226  H HB2  . ALA B 2 26  ? 142.469 77.302  147.130 1.00 70.75  ?  21  ALA B HB2  1 
ATOM   4227  H HB3  . ALA B 2 26  ? 143.536 76.520  148.011 1.00 70.75  ?  21  ALA B HB3  1 
ATOM   4228  N N    . ARG B 2 27  ? 142.538 77.313  144.204 1.00 67.23  ?  22  ARG B N    1 
ATOM   4229  C CA   . ARG B 2 27  ? 141.744 77.268  142.981 1.00 67.23  ?  22  ARG B CA   1 
ATOM   4230  C C    . ARG B 2 27  ? 142.580 76.792  141.800 1.00 67.23  ?  22  ARG B C    1 
ATOM   4231  O O    . ARG B 2 27  ? 142.108 76.004  140.972 1.00 67.23  ?  22  ARG B O    1 
ATOM   4232  C CB   . ARG B 2 27  ? 141.151 78.648  142.696 1.00 67.23  ?  22  ARG B CB   1 
ATOM   4233  C CG   . ARG B 2 27  ? 139.961 78.999  143.572 1.00 67.23  ?  22  ARG B CG   1 
ATOM   4234  C CD   . ARG B 2 27  ? 139.100 80.075  142.936 1.00 67.23  ?  22  ARG B CD   1 
ATOM   4235  N NE   . ARG B 2 27  ? 139.827 81.331  142.752 1.00 67.23  ?  22  ARG B NE   1 
ATOM   4236  C CZ   . ARG B 2 27  ? 139.610 82.449  143.441 1.00 67.23  ?  22  ARG B CZ   1 
ATOM   4237  N NH1  . ARG B 2 27  ? 140.333 83.530  143.182 1.00 67.23  1  22  ARG B NH1  1 
ATOM   4238  N NH2  . ARG B 2 27  ? 138.681 82.501  144.389 1.00 67.23  ?  22  ARG B NH2  1 
ATOM   4239  H H    . ARG B 2 27  ? 142.643 78.100  144.535 1.00 67.23  ?  22  ARG B H    1 
ATOM   4240  H HA   . ARG B 2 27  ? 141.011 76.644  143.101 1.00 67.23  ?  22  ARG B HA   1 
ATOM   4241  H HB2  . ARG B 2 27  ? 141.835 79.319  142.843 1.00 67.23  ?  22  ARG B HB2  1 
ATOM   4242  H HB3  . ARG B 2 27  ? 140.856 78.676  141.772 1.00 67.23  ?  22  ARG B HB3  1 
ATOM   4243  H HG2  . ARG B 2 27  ? 139.413 78.209  143.701 1.00 67.23  ?  22  ARG B HG2  1 
ATOM   4244  H HG3  . ARG B 2 27  ? 140.279 79.329  144.427 1.00 67.23  ?  22  ARG B HG3  1 
ATOM   4245  H HD2  . ARG B 2 27  ? 138.822 79.769  142.060 1.00 67.23  ?  22  ARG B HD2  1 
ATOM   4246  H HD3  . ARG B 2 27  ? 138.322 80.228  143.491 1.00 67.23  ?  22  ARG B HD3  1 
ATOM   4247  H HE   . ARG B 2 27  ? 140.437 81.351  142.146 1.00 67.23  ?  22  ARG B HE   1 
ATOM   4248  H HH11 . ARG B 2 27  ? 140.937 83.506  142.570 1.00 67.23  ?  22  ARG B HH11 1 
ATOM   4249  H HH12 . ARG B 2 27  ? 140.198 84.254  143.626 1.00 67.23  ?  22  ARG B HH12 1 
ATOM   4250  H HH21 . ARG B 2 27  ? 138.202 81.813  144.573 1.00 67.23  ?  22  ARG B HH21 1 
ATOM   4251  H HH22 . ARG B 2 27  ? 138.557 83.233  144.824 1.00 67.23  ?  22  ARG B HH22 1 
ATOM   4252  N N    . LYS B 2 28  ? 143.825 77.263  141.704 1.00 68.15  ?  23  LYS B N    1 
ATOM   4253  C CA   . LYS B 2 28  ? 144.690 76.848  140.605 1.00 68.15  ?  23  LYS B CA   1 
ATOM   4254  C C    . LYS B 2 28  ? 144.977 75.354  140.652 1.00 68.15  ?  23  LYS B C    1 
ATOM   4255  O O    . LYS B 2 28  ? 145.038 74.701  139.604 1.00 68.15  ?  23  LYS B O    1 
ATOM   4256  C CB   . LYS B 2 28  ? 145.997 77.640  140.643 1.00 68.15  ?  23  LYS B CB   1 
ATOM   4257  C CG   . LYS B 2 28  ? 146.927 77.353  139.473 1.00 68.15  ?  23  LYS B CG   1 
ATOM   4258  C CD   . LYS B 2 28  ? 147.645 78.613  138.999 1.00 68.15  ?  23  LYS B CD   1 
ATOM   4259  C CE   . LYS B 2 28  ? 148.156 78.479  137.570 1.00 68.15  ?  23  LYS B CE   1 
ATOM   4260  N NZ   . LYS B 2 28  ? 147.098 78.061  136.608 1.00 68.15  1  23  LYS B NZ   1 
ATOM   4261  H H    . LYS B 2 28  ? 144.187 77.815  142.256 1.00 68.15  ?  23  LYS B H    1 
ATOM   4262  H HA   . LYS B 2 28  ? 144.246 77.042  139.765 1.00 68.15  ?  23  LYS B HA   1 
ATOM   4263  H HB2  . LYS B 2 28  ? 145.785 78.586  140.635 1.00 68.15  ?  23  LYS B HB2  1 
ATOM   4264  H HB3  . LYS B 2 28  ? 146.472 77.418  141.459 1.00 68.15  ?  23  LYS B HB3  1 
ATOM   4265  H HG2  . LYS B 2 28  ? 147.598 76.710  139.752 1.00 68.15  ?  23  LYS B HG2  1 
ATOM   4266  H HG3  . LYS B 2 28  ? 146.406 76.995  138.739 1.00 68.15  ?  23  LYS B HG3  1 
ATOM   4267  H HD2  . LYS B 2 28  ? 147.031 79.363  139.026 1.00 68.15  ?  23  LYS B HD2  1 
ATOM   4268  H HD3  . LYS B 2 28  ? 148.405 78.782  139.577 1.00 68.15  ?  23  LYS B HD3  1 
ATOM   4269  H HE2  . LYS B 2 28  ? 148.504 79.337  137.278 1.00 68.15  ?  23  LYS B HE2  1 
ATOM   4270  H HE3  . LYS B 2 28  ? 148.860 77.812  137.548 1.00 68.15  ?  23  LYS B HE3  1 
ATOM   4271  H HZ1  . LYS B 2 28  ? 147.381 78.183  135.773 1.00 68.15  ?  23  LYS B HZ1  1 
ATOM   4272  H HZ2  . LYS B 2 28  ? 146.903 77.200  136.723 1.00 68.15  ?  23  LYS B HZ2  1 
ATOM   4273  H HZ3  . LYS B 2 28  ? 146.362 78.545  136.736 1.00 68.15  ?  23  LYS B HZ3  1 
ATOM   4274  N N    . ALA B 2 29  ? 145.159 74.796  141.852 1.00 68.59  ?  24  ALA B N    1 
ATOM   4275  C CA   . ALA B 2 29  ? 145.441 73.369  141.967 1.00 68.59  ?  24  ALA B CA   1 
ATOM   4276  C C    . ALA B 2 29  ? 144.312 72.524  141.393 1.00 68.59  ?  24  ALA B C    1 
ATOM   4277  O O    . ALA B 2 29  ? 144.560 71.422  140.890 1.00 68.59  ?  24  ALA B O    1 
ATOM   4278  C CB   . ALA B 2 29  ? 145.685 73.001  143.430 1.00 68.59  ?  24  ALA B CB   1 
ATOM   4279  H H    . ALA B 2 29  ? 145.124 75.216  142.601 1.00 68.59  ?  24  ALA B H    1 
ATOM   4280  H HA   . ALA B 2 29  ? 146.248 73.167  141.469 1.00 68.59  ?  24  ALA B HA   1 
ATOM   4281  H HB1  . ALA B 2 29  ? 145.871 72.051  143.490 1.00 68.59  ?  24  ALA B HB1  1 
ATOM   4282  H HB2  . ALA B 2 29  ? 146.444 73.508  143.760 1.00 68.59  ?  24  ALA B HB2  1 
ATOM   4283  H HB3  . ALA B 2 29  ? 144.893 73.217  143.946 1.00 68.59  ?  24  ALA B HB3  1 
ATOM   4284  N N    . CYS B 2 30  ? 143.073 73.015  141.457 1.00 65.79  ?  25  CYS B N    1 
ATOM   4285  C CA   . CYS B 2 30  ? 141.941 72.277  140.913 1.00 65.79  ?  25  CYS B CA   1 
ATOM   4286  C C    . CYS B 2 30  ? 141.813 72.426  139.403 1.00 65.79  ?  25  CYS B C    1 
ATOM   4287  O O    . CYS B 2 30  ? 141.011 71.712  138.791 1.00 65.79  ?  25  CYS B O    1 
ATOM   4288  C CB   . CYS B 2 30  ? 140.644 72.738  141.582 1.00 65.79  ?  25  CYS B CB   1 
ATOM   4289  S SG   . CYS B 2 30  ? 140.562 72.390  143.353 1.00 65.79  ?  25  CYS B SG   1 
ATOM   4290  H H    . CYS B 2 30  ? 142.866 73.771  141.810 1.00 65.79  ?  25  CYS B H    1 
ATOM   4291  H HA   . CYS B 2 30  ? 142.057 71.335  141.110 1.00 65.79  ?  25  CYS B HA   1 
ATOM   4292  H HB2  . CYS B 2 30  ? 140.557 73.697  141.465 1.00 65.79  ?  25  CYS B HB2  1 
ATOM   4293  H HB3  . CYS B 2 30  ? 139.897 72.287  141.157 1.00 65.79  ?  25  CYS B HB3  1 
ATOM   4294  H HG   . CYS B 2 30  ? 141.470 72.948  143.905 1.00 65.79  ?  25  CYS B HG   1 
ATOM   4295  N N    . ALA B 2 31  ? 142.581 73.329  138.790 1.00 65.32  ?  26  ALA B N    1 
ATOM   4296  C CA   . ALA B 2 31  ? 142.521 73.551  137.345 1.00 65.32  ?  26  ALA B CA   1 
ATOM   4297  C C    . ALA B 2 31  ? 143.394 72.513  136.637 1.00 65.32  ?  26  ALA B C    1 
ATOM   4298  O O    . ALA B 2 31  ? 144.397 72.819  135.989 1.00 65.32  ?  26  ALA B O    1 
ATOM   4299  C CB   . ALA B 2 31  ? 142.954 74.970  137.006 1.00 65.32  ?  26  ALA B CB   1 
ATOM   4300  H H    . ALA B 2 31  ? 143.150 73.832  139.193 1.00 65.32  ?  26  ALA B H    1 
ATOM   4301  H HA   . ALA B 2 31  ? 141.608 73.434  137.041 1.00 65.32  ?  26  ALA B HA   1 
ATOM   4302  H HB1  . ALA B 2 31  ? 142.887 75.100  136.047 1.00 65.32  ?  26  ALA B HB1  1 
ATOM   4303  H HB2  . ALA B 2 31  ? 143.871 75.098  137.295 1.00 65.32  ?  26  ALA B HB2  1 
ATOM   4304  H HB3  . ALA B 2 31  ? 142.372 75.595  137.467 1.00 65.32  ?  26  ALA B HB3  1 
ATOM   4305  N N    . ASP B 2 32  ? 142.985 71.250  136.775 1.00 63.99  ?  27  ASP B N    1 
ATOM   4306  C CA   . ASP B 2 32  ? 143.710 70.167  136.119 1.00 63.99  ?  27  ASP B CA   1 
ATOM   4307  C C    . ASP B 2 32  ? 143.600 70.270  134.602 1.00 63.99  ?  27  ASP B C    1 
ATOM   4308  O O    . ASP B 2 32  ? 144.582 70.039  133.887 1.00 63.99  ?  27  ASP B O    1 
ATOM   4309  C CB   . ASP B 2 32  ? 143.187 68.815  136.607 1.00 63.99  ?  27  ASP B CB   1 
ATOM   4310  C CG   . ASP B 2 32  ? 141.715 68.615  136.307 1.00 63.99  ?  27  ASP B CG   1 
ATOM   4311  O OD1  . ASP B 2 32  ? 141.020 69.617  136.035 1.00 63.99  ?  27  ASP B OD1  1 
ATOM   4312  O OD2  . ASP B 2 32  ? 141.253 67.456  136.344 1.00 63.99  -1 27  ASP B OD2  1 
ATOM   4313  H H    . ASP B 2 32  ? 142.303 71.000  137.236 1.00 63.99  ?  27  ASP B H    1 
ATOM   4314  H HA   . ASP B 2 32  ? 144.649 70.227  136.355 1.00 63.99  ?  27  ASP B HA   1 
ATOM   4315  H HB2  . ASP B 2 32  ? 143.683 68.107  136.167 1.00 63.99  ?  27  ASP B HB2  1 
ATOM   4316  H HB3  . ASP B 2 32  ? 143.308 68.758  137.568 1.00 63.99  ?  27  ASP B HB3  1 
ATOM   4317  N N    . ALA B 2 33  ? 142.418 70.614  134.095 1.00 63.57  ?  28  ALA B N    1 
ATOM   4318  C CA   . ALA B 2 33  ? 142.206 70.751  132.663 1.00 63.57  ?  28  ALA B CA   1 
ATOM   4319  C C    . ALA B 2 33  ? 141.117 71.784  132.419 1.00 63.57  ?  28  ALA B C    1 
ATOM   4320  O O    . ALA B 2 33  ? 140.295 72.061  133.297 1.00 63.57  ?  28  ALA B O    1 
ATOM   4321  C CB   . ALA B 2 33  ? 141.822 69.413  132.018 1.00 63.57  ?  28  ALA B CB   1 
ATOM   4322  H H    . ALA B 2 33  ? 141.718 70.774  134.568 1.00 63.57  ?  28  ALA B H    1 
ATOM   4323  H HA   . ALA B 2 33  ? 143.023 71.066  132.246 1.00 63.57  ?  28  ALA B HA   1 
ATOM   4324  H HB1  . ALA B 2 33  ? 141.691 69.548  131.067 1.00 63.57  ?  28  ALA B HB1  1 
ATOM   4325  H HB2  . ALA B 2 33  ? 141.002 69.091  132.424 1.00 63.57  ?  28  ALA B HB2  1 
ATOM   4326  H HB3  . ALA B 2 33  ? 142.538 68.775  132.167 1.00 63.57  ?  28  ALA B HB3  1 
ATOM   4327  N N    . THR B 2 34  ? 141.120 72.351  131.217 1.00 61.30  ?  29  THR B N    1 
ATOM   4328  C CA   . THR B 2 34  ? 140.155 73.371  130.838 1.00 61.30  ?  29  THR B CA   1 
ATOM   4329  C C    . THR B 2 34  ? 138.940 72.738  130.171 1.00 61.30  ?  29  THR B C    1 
ATOM   4330  O O    . THR B 2 34  ? 139.044 71.724  129.475 1.00 61.30  ?  29  THR B O    1 
ATOM   4331  C CB   . THR B 2 34  ? 140.787 74.393  129.890 1.00 61.30  ?  29  THR B CB   1 
ATOM   4332  O OG1  . THR B 2 34  ? 141.061 73.774  128.627 1.00 61.30  ?  29  THR B OG1  1 
ATOM   4333  C CG2  . THR B 2 34  ? 142.081 74.941  130.476 1.00 61.30  ?  29  THR B CG2  1 
ATOM   4334  H H    . THR B 2 34  ? 141.681 72.157  130.595 1.00 61.30  ?  29  THR B H    1 
ATOM   4335  H HA   . THR B 2 34  ? 139.855 73.840  131.632 1.00 61.30  ?  29  THR B HA   1 
ATOM   4336  H HB   . THR B 2 34  ? 140.174 75.133  129.759 1.00 61.30  ?  29  THR B HB   1 
ATOM   4337  H HG1  . THR B 2 34  ? 141.409 74.331  128.103 1.00 61.30  ?  29  THR B HG1  1 
ATOM   4338  H HG21 . THR B 2 34  ? 142.414 75.665  129.923 1.00 61.30  ?  29  THR B HG21 1 
ATOM   4339  H HG22 . THR B 2 34  ? 141.922 75.277  131.372 1.00 61.30  ?  29  THR B HG22 1 
ATOM   4340  H HG23 . THR B 2 34  ? 142.751 74.241  130.516 1.00 61.30  ?  29  THR B HG23 1 
ATOM   4341  N N    . LEU B 2 35  ? 137.775 73.353  130.394 1.00 53.90  ?  30  LEU B N    1 
ATOM   4342  C CA   . LEU B 2 35  ? 136.548 72.852  129.785 1.00 53.90  ?  30  LEU B CA   1 
ATOM   4343  C C    . LEU B 2 35  ? 136.628 72.872  128.264 1.00 53.90  ?  30  LEU B C    1 
ATOM   4344  O O    . LEU B 2 35  ? 136.031 72.017  127.600 1.00 53.90  ?  30  LEU B O    1 
ATOM   4345  C CB   . LEU B 2 35  ? 135.353 73.681  130.259 1.00 53.90  ?  30  LEU B CB   1 
ATOM   4346  C CG   . LEU B 2 35  ? 133.985 73.358  129.647 1.00 53.90  ?  30  LEU B CG   1 
ATOM   4347  C CD1  . LEU B 2 35  ? 133.674 71.869  129.704 1.00 53.90  ?  30  LEU B CD1  1 
ATOM   4348  C CD2  . LEU B 2 35  ? 132.893 74.155  130.343 1.00 53.90  ?  30  LEU B CD2  1 
ATOM   4349  H H    . LEU B 2 35  ? 137.673 74.050  130.886 1.00 53.90  ?  30  LEU B H    1 
ATOM   4350  H HA   . LEU B 2 35  ? 136.411 71.934  130.067 1.00 53.90  ?  30  LEU B HA   1 
ATOM   4351  H HB2  . LEU B 2 35  ? 135.269 73.566  131.218 1.00 53.90  ?  30  LEU B HB2  1 
ATOM   4352  H HB3  . LEU B 2 35  ? 135.538 74.613  130.065 1.00 53.90  ?  30  LEU B HB3  1 
ATOM   4353  H HG   . LEU B 2 35  ? 133.991 73.622  128.713 1.00 53.90  ?  30  LEU B HG   1 
ATOM   4354  H HD11 . LEU B 2 35  ? 134.389 71.371  129.281 1.00 53.90  ?  30  LEU B HD11 1 
ATOM   4355  H HD12 . LEU B 2 35  ? 132.839 71.705  129.240 1.00 53.90  ?  30  LEU B HD12 1 
ATOM   4356  H HD13 . LEU B 2 35  ? 133.591 71.606  130.633 1.00 53.90  ?  30  LEU B HD13 1 
ATOM   4357  H HD21 . LEU B 2 35  ? 132.756 73.792  131.232 1.00 53.90  ?  30  LEU B HD21 1 
ATOM   4358  H HD22 . LEU B 2 35  ? 132.075 74.084  129.827 1.00 53.90  ?  30  LEU B HD22 1 
ATOM   4359  H HD23 . LEU B 2 35  ? 133.168 75.083  130.402 1.00 53.90  ?  30  LEU B HD23 1 
ATOM   4360  N N    . SER B 2 36  ? 137.357 73.834  127.695 1.00 58.20  ?  31  SER B N    1 
ATOM   4361  C CA   . SER B 2 36  ? 137.455 73.922  126.241 1.00 58.20  ?  31  SER B CA   1 
ATOM   4362  C C    . SER B 2 36  ? 138.123 72.684  125.657 1.00 58.20  ?  31  SER B C    1 
ATOM   4363  O O    . SER B 2 36  ? 137.671 72.147  124.639 1.00 58.20  ?  31  SER B O    1 
ATOM   4364  C CB   . SER B 2 36  ? 138.224 75.182  125.846 1.00 58.20  ?  31  SER B CB   1 
ATOM   4365  O OG   . SER B 2 36  ? 137.699 76.325  126.500 1.00 58.20  ?  31  SER B OG   1 
ATOM   4366  H H    . SER B 2 36  ? 137.797 74.437  128.122 1.00 58.20  ?  31  SER B H    1 
ATOM   4367  H HA   . SER B 2 36  ? 136.562 73.985  125.868 1.00 58.20  ?  31  SER B HA   1 
ATOM   4368  H HB2  . SER B 2 36  ? 139.154 75.075  126.097 1.00 58.20  ?  31  SER B HB2  1 
ATOM   4369  H HB3  . SER B 2 36  ? 138.151 75.307  124.887 1.00 58.20  ?  31  SER B HB3  1 
ATOM   4370  H HG   . SER B 2 36  ? 138.141 77.006  126.287 1.00 58.20  ?  31  SER B HG   1 
ATOM   4371  N N    . GLN B 2 37  ? 139.202 72.216  126.287 1.00 61.13  ?  32  GLN B N    1 
ATOM   4372  C CA   . GLN B 2 37  ? 139.897 71.034  125.788 1.00 61.13  ?  32  GLN B CA   1 
ATOM   4373  C C    . GLN B 2 37  ? 139.006 69.800  125.869 1.00 61.13  ?  32  GLN B C    1 
ATOM   4374  O O    . GLN B 2 37  ? 138.987 68.973  124.950 1.00 61.13  ?  32  GLN B O    1 
ATOM   4375  C CB   . GLN B 2 37  ? 141.188 70.816  126.578 1.00 61.13  ?  32  GLN B CB   1 
ATOM   4376  C CG   . GLN B 2 37  ? 142.296 71.801  126.241 1.00 61.13  ?  32  GLN B CG   1 
ATOM   4377  C CD   . GLN B 2 37  ? 142.974 71.490  124.920 1.00 61.13  ?  32  GLN B CD   1 
ATOM   4378  O OE1  . GLN B 2 37  ? 142.988 72.316  124.007 1.00 61.13  ?  32  GLN B OE1  1 
ATOM   4379  N NE2  . GLN B 2 37  ? 143.543 70.295  124.813 1.00 61.13  ?  32  GLN B NE2  1 
ATOM   4380  H H    . GLN B 2 37  ? 139.547 72.562  126.995 1.00 61.13  ?  32  GLN B H    1 
ATOM   4381  H HA   . GLN B 2 37  ? 140.133 71.174  124.858 1.00 61.13  ?  32  GLN B HA   1 
ATOM   4382  H HB2  . GLN B 2 37  ? 140.992 70.905  127.524 1.00 61.13  ?  32  GLN B HB2  1 
ATOM   4383  H HB3  . GLN B 2 37  ? 141.518 69.922  126.396 1.00 61.13  ?  32  GLN B HB3  1 
ATOM   4384  H HG2  . GLN B 2 37  ? 141.919 72.693  126.182 1.00 61.13  ?  32  GLN B HG2  1 
ATOM   4385  H HG3  . GLN B 2 37  ? 142.969 71.771  126.938 1.00 61.13  ?  32  GLN B HG3  1 
ATOM   4386  H HE21 . GLN B 2 37  ? 143.513 69.744  125.473 1.00 61.13  ?  32  GLN B HE21 1 
ATOM   4387  H HE22 . GLN B 2 37  ? 143.940 70.071  124.084 1.00 61.13  ?  32  GLN B HE22 1 
ATOM   4388  N N    . ILE B 2 38  ? 138.258 69.661  126.965 1.00 57.65  ?  33  ILE B N    1 
ATOM   4389  C CA   . ILE B 2 38  ? 137.433 68.472  127.155 1.00 57.65  ?  33  ILE B CA   1 
ATOM   4390  C C    . ILE B 2 38  ? 136.305 68.433  126.132 1.00 57.65  ?  33  ILE B C    1 
ATOM   4391  O O    . ILE B 2 38  ? 135.933 67.360  125.640 1.00 57.65  ?  33  ILE B O    1 
ATOM   4392  C CB   . ILE B 2 38  ? 136.894 68.426  128.597 1.00 57.65  ?  33  ILE B CB   1 
ATOM   4393  C CG1  . ILE B 2 38  ? 138.051 68.491  129.600 1.00 57.65  ?  33  ILE B CG1  1 
ATOM   4394  C CG2  . ILE B 2 38  ? 136.079 67.159  128.820 1.00 57.65  ?  33  ILE B CG2  1 
ATOM   4395  C CD1  . ILE B 2 38  ? 137.615 68.459  131.052 1.00 57.65  ?  33  ILE B CD1  1 
ATOM   4396  H H    . ILE B 2 38  ? 138.212 70.235  127.603 1.00 57.65  ?  33  ILE B H    1 
ATOM   4397  H HA   . ILE B 2 38  ? 137.984 67.685  127.020 1.00 57.65  ?  33  ILE B HA   1 
ATOM   4398  H HB   . ILE B 2 38  ? 136.319 69.195  128.738 1.00 57.65  ?  33  ILE B HB   1 
ATOM   4399  H HG12 . ILE B 2 38  ? 138.634 67.730  129.451 1.00 57.65  ?  33  ILE B HG12 1 
ATOM   4400  H HG13 . ILE B 2 38  ? 138.545 69.314  129.462 1.00 57.65  ?  33  ILE B HG13 1 
ATOM   4401  H HG21 . ILE B 2 38  ? 135.696 67.179  129.711 1.00 57.65  ?  33  ILE B HG21 1 
ATOM   4402  H HG22 . ILE B 2 38  ? 135.368 67.115  128.163 1.00 57.65  ?  33  ILE B HG22 1 
ATOM   4403  H HG23 . ILE B 2 38  ? 136.663 66.390  128.728 1.00 57.65  ?  33  ILE B HG23 1 
ATOM   4404  H HD11 . ILE B 2 38  ? 138.372 68.690  131.613 1.00 57.65  ?  33  ILE B HD11 1 
ATOM   4405  H HD12 . ILE B 2 38  ? 136.900 69.103  131.180 1.00 57.65  ?  33  ILE B HD12 1 
ATOM   4406  H HD13 . ILE B 2 38  ? 137.300 67.568  131.270 1.00 57.65  ?  33  ILE B HD13 1 
ATOM   4407  N N    . THR B 2 39  ? 135.743 69.592  125.794 1.00 55.18  ?  34  THR B N    1 
ATOM   4408  C CA   . THR B 2 39  ? 134.605 69.662  124.885 1.00 55.18  ?  34  THR B CA   1 
ATOM   4409  C C    . THR B 2 39  ? 135.011 69.677  123.417 1.00 55.18  ?  34  THR B C    1 
ATOM   4410  O O    . THR B 2 39  ? 134.150 69.893  122.558 1.00 55.18  ?  34  THR B O    1 
ATOM   4411  C CB   . THR B 2 39  ? 133.764 70.906  125.188 1.00 55.18  ?  34  THR B CB   1 
ATOM   4412  O OG1  . THR B 2 39  ? 134.591 72.076  125.133 1.00 55.18  ?  34  THR B OG1  1 
ATOM   4413  C CG2  . THR B 2 39  ? 133.126 70.798  126.564 1.00 55.18  ?  34  THR B CG2  1 
ATOM   4414  H H    . THR B 2 39  ? 136.007 70.358  126.082 1.00 55.18  ?  34  THR B H    1 
ATOM   4415  H HA   . THR B 2 39  ? 134.044 68.884  125.028 1.00 55.18  ?  34  THR B HA   1 
ATOM   4416  H HB   . THR B 2 39  ? 133.055 70.983  124.529 1.00 55.18  ?  34  THR B HB   1 
ATOM   4417  H HG1  . THR B 2 39  ? 135.157 72.058  125.753 1.00 55.18  ?  34  THR B HG1  1 
ATOM   4418  H HG21 . THR B 2 39  ? 132.672 71.626  126.786 1.00 55.18  ?  34  THR B HG21 1 
ATOM   4419  H HG22 . THR B 2 39  ? 133.807 70.621  127.231 1.00 55.18  ?  34  THR B HG22 1 
ATOM   4420  H HG23 . THR B 2 39  ? 132.482 70.072  126.574 1.00 55.18  ?  34  THR B HG23 1 
ATOM   4421  N N    . ASN B 2 40  ? 136.290 69.464  123.105 1.00 56.89  ?  35  ASN B N    1 
ATOM   4422  C CA   . ASN B 2 40  ? 136.717 69.470  121.710 1.00 56.89  ?  35  ASN B CA   1 
ATOM   4423  C C    . ASN B 2 40  ? 136.084 68.332  120.918 1.00 56.89  ?  35  ASN B C    1 
ATOM   4424  O O    . ASN B 2 40  ? 135.961 68.426  119.691 1.00 56.89  ?  35  ASN B O    1 
ATOM   4425  C CB   . ASN B 2 40  ? 138.242 69.383  121.631 1.00 56.89  ?  35  ASN B CB   1 
ATOM   4426  C CG   . ASN B 2 40  ? 138.831 70.342  120.614 1.00 56.89  ?  35  ASN B CG   1 
ATOM   4427  O OD1  . ASN B 2 40  ? 138.157 70.761  119.673 1.00 56.89  ?  35  ASN B OD1  1 
ATOM   4428  N ND2  . ASN B 2 40  ? 140.098 70.694  120.799 1.00 56.89  ?  35  ASN B ND2  1 
ATOM   4429  H H    . ASN B 2 40  ? 136.919 69.317  123.673 1.00 56.89  ?  35  ASN B H    1 
ATOM   4430  H HA   . ASN B 2 40  ? 136.442 70.307  121.303 1.00 56.89  ?  35  ASN B HA   1 
ATOM   4431  H HB2  . ASN B 2 40  ? 138.619 69.599  122.498 1.00 56.89  ?  35  ASN B HB2  1 
ATOM   4432  H HB3  . ASN B 2 40  ? 138.494 68.482  121.374 1.00 56.89  ?  35  ASN B HB3  1 
ATOM   4433  H HD21 . ASN B 2 40  ? 140.538 70.381  121.468 1.00 56.89  ?  35  ASN B HD21 1 
ATOM   4434  H HD22 . ASN B 2 40  ? 140.479 71.236  120.250 1.00 56.89  ?  35  ASN B HD22 1 
ATOM   4435  N N    . ASN B 2 41  ? 135.678 67.254  121.592 1.00 56.38  ?  36  ASN B N    1 
ATOM   4436  C CA   . ASN B 2 41  ? 135.180 66.072  120.898 1.00 56.38  ?  36  ASN B CA   1 
ATOM   4437  C C    . ASN B 2 41  ? 133.691 66.142  120.581 1.00 56.38  ?  36  ASN B C    1 
ATOM   4438  O O    . ASN B 2 41  ? 133.249 65.503  119.621 1.00 56.38  ?  36  ASN B O    1 
ATOM   4439  C CB   . ASN B 2 41  ? 135.455 64.819  121.734 1.00 56.38  ?  36  ASN B CB   1 
ATOM   4440  C CG   . ASN B 2 41  ? 136.921 64.663  122.088 1.00 56.38  ?  36  ASN B CG   1 
ATOM   4441  O OD1  . ASN B 2 41  ? 137.739 65.535  121.795 1.00 56.38  ?  36  ASN B OD1  1 
ATOM   4442  N ND2  . ASN B 2 41  ? 137.261 63.547  122.724 1.00 56.38  ?  36  ASN B ND2  1 
ATOM   4443  H H    . ASN B 2 41  ? 135.681 67.184  122.450 1.00 56.38  ?  36  ASN B H    1 
ATOM   4444  H HA   . ASN B 2 41  ? 135.657 65.978  120.058 1.00 56.38  ?  36  ASN B HA   1 
ATOM   4445  H HB2  . ASN B 2 41  ? 134.949 64.871  122.560 1.00 56.38  ?  36  ASN B HB2  1 
ATOM   4446  H HB3  . ASN B 2 41  ? 135.184 64.036  121.228 1.00 56.38  ?  36  ASN B HB3  1 
ATOM   4447  H HD21 . ASN B 2 41  ? 136.661 62.959  122.912 1.00 56.38  ?  36  ASN B HD21 1 
ATOM   4448  H HD22 . ASN B 2 41  ? 138.080 63.411  122.947 1.00 56.38  ?  36  ASN B HD22 1 
ATOM   4449  N N    . ILE B 2 42  ? 132.910 66.897  121.356 1.00 50.86  ?  37  ILE B N    1 
ATOM   4450  C CA   . ILE B 2 42  ? 131.463 66.891  121.186 1.00 50.86  ?  37  ILE B CA   1 
ATOM   4451  C C    . ILE B 2 42  ? 131.093 67.518  119.848 1.00 50.86  ?  37  ILE B C    1 
ATOM   4452  O O    . ILE B 2 42  ? 131.770 68.432  119.357 1.00 50.86  ?  37  ILE B O    1 
ATOM   4453  C CB   . ILE B 2 42  ? 130.778 67.629  122.348 1.00 50.86  ?  37  ILE B CB   1 
ATOM   4454  C CG1  . ILE B 2 42  ? 129.271 67.365  122.331 1.00 50.86  ?  37  ILE B CG1  1 
ATOM   4455  C CG2  . ILE B 2 42  ? 131.039 69.123  122.259 1.00 50.86  ?  37  ILE B CG2  1 
ATOM   4456  C CD1  . ILE B 2 42  ? 128.617 67.520  123.683 1.00 50.86  ?  37  ILE B CD1  1 
ATOM   4457  H H    . ILE B 2 42  ? 133.193 67.413  121.982 1.00 50.86  ?  37  ILE B H    1 
ATOM   4458  H HA   . ILE B 2 42  ? 131.149 65.973  121.184 1.00 50.86  ?  37  ILE B HA   1 
ATOM   4459  H HB   . ILE B 2 42  ? 131.143 67.299  123.184 1.00 50.86  ?  37  ILE B HB   1 
ATOM   4460  H HG12 . ILE B 2 42  ? 128.847 67.989  121.721 1.00 50.86  ?  37  ILE B HG12 1 
ATOM   4461  H HG13 . ILE B 2 42  ? 129.115 66.456  122.030 1.00 50.86  ?  37  ILE B HG13 1 
ATOM   4462  H HG21 . ILE B 2 42  ? 131.971 69.261  122.038 1.00 50.86  ?  37  ILE B HG21 1 
ATOM   4463  H HG22 . ILE B 2 42  ? 130.837 69.532  123.115 1.00 50.86  ?  37  ILE B HG22 1 
ATOM   4464  H HG23 . ILE B 2 42  ? 130.477 69.507  121.568 1.00 50.86  ?  37  ILE B HG23 1 
ATOM   4465  H HD11 . ILE B 2 42  ? 129.013 66.884  124.298 1.00 50.86  ?  37  ILE B HD11 1 
ATOM   4466  H HD12 . ILE B 2 42  ? 127.666 67.350  123.594 1.00 50.86  ?  37  ILE B HD12 1 
ATOM   4467  H HD13 . ILE B 2 42  ? 128.764 68.425  124.001 1.00 50.86  ?  37  ILE B HD13 1 
ATOM   4468  N N    . ASP B 2 43  ? 130.014 67.024  119.254 1.00 51.67  ?  38  ASP B N    1 
ATOM   4469  C CA   . ASP B 2 43  ? 129.533 67.571  117.995 1.00 51.67  ?  38  ASP B CA   1 
ATOM   4470  C C    . ASP B 2 43  ? 129.068 69.012  118.204 1.00 51.67  ?  38  ASP B C    1 
ATOM   4471  O O    . ASP B 2 43  ? 128.232 69.264  119.082 1.00 51.67  ?  38  ASP B O    1 
ATOM   4472  C CB   . ASP B 2 43  ? 128.384 66.710  117.465 1.00 51.67  ?  38  ASP B CB   1 
ATOM   4473  C CG   . ASP B 2 43  ? 127.957 67.089  116.059 1.00 51.67  ?  38  ASP B CG   1 
ATOM   4474  O OD1  . ASP B 2 43  ? 128.523 68.043  115.491 1.00 51.67  ?  38  ASP B OD1  1 
ATOM   4475  O OD2  . ASP B 2 43  ? 127.049 66.425  115.517 1.00 51.67  -1 38  ASP B OD2  1 
ATOM   4476  H H    . ASP B 2 43  ? 129.544 66.371  119.559 1.00 51.67  ?  38  ASP B H    1 
ATOM   4477  H HA   . ASP B 2 43  ? 130.252 67.549  117.347 1.00 51.67  ?  38  ASP B HA   1 
ATOM   4478  H HB2  . ASP B 2 43  ? 128.669 65.782  117.450 1.00 51.67  ?  38  ASP B HB2  1 
ATOM   4479  H HB3  . ASP B 2 43  ? 127.617 66.811  118.050 1.00 51.67  ?  38  ASP B HB3  1 
ATOM   4480  N N    . PRO B 2 44  ? 129.576 69.977  117.437 1.00 48.96  ?  39  PRO B N    1 
ATOM   4481  C CA   . PRO B 2 44  ? 129.091 71.353  117.582 1.00 48.96  ?  39  PRO B CA   1 
ATOM   4482  C C    . PRO B 2 44  ? 127.647 71.499  117.128 1.00 48.96  ?  39  PRO B C    1 
ATOM   4483  O O    . PRO B 2 44  ? 127.145 70.752  116.286 1.00 48.96  ?  39  PRO B O    1 
ATOM   4484  C CB   . PRO B 2 44  ? 130.039 72.163  116.692 1.00 48.96  ?  39  PRO B CB   1 
ATOM   4485  C CG   . PRO B 2 44  ? 130.514 71.196  115.677 1.00 48.96  ?  39  PRO B CG   1 
ATOM   4486  C CD   . PRO B 2 44  ? 130.624 69.882  116.403 1.00 48.96  ?  39  PRO B CD   1 
ATOM   4487  H HA   . PRO B 2 44  ? 129.177 71.651  118.502 1.00 48.96  ?  39  PRO B HA   1 
ATOM   4488  H HB2  . PRO B 2 44  ? 129.549 72.887  116.271 1.00 48.96  ?  39  PRO B HB2  1 
ATOM   4489  H HB3  . PRO B 2 44  ? 130.776 72.508  117.217 1.00 48.96  ?  39  PRO B HB3  1 
ATOM   4490  H HG2  . PRO B 2 44  ? 129.867 71.136  114.957 1.00 48.96  ?  39  PRO B HG2  1 
ATOM   4491  H HG3  . PRO B 2 44  ? 131.379 71.476  115.339 1.00 48.96  ?  39  PRO B HG3  1 
ATOM   4492  H HD2  . PRO B 2 44  ? 130.457 69.149  115.795 1.00 48.96  ?  39  PRO B HD2  1 
ATOM   4493  H HD3  . PRO B 2 44  ? 131.497 69.801  116.819 1.00 48.96  ?  39  PRO B HD3  1 
ATOM   4494  N N    . VAL B 2 45  ? 126.978 72.496  117.712 1.00 41.95  ?  40  VAL B N    1 
ATOM   4495  C CA   . VAL B 2 45  ? 125.586 72.766  117.378 1.00 41.95  ?  40  VAL B CA   1 
ATOM   4496  C C    . VAL B 2 45  ? 125.438 73.219  115.933 1.00 41.95  ?  40  VAL B C    1 
ATOM   4497  O O    . VAL B 2 45  ? 124.342 73.138  115.367 1.00 41.95  ?  40  VAL B O    1 
ATOM   4498  C CB   . VAL B 2 45  ? 125.008 73.819  118.348 1.00 41.95  ?  40  VAL B CB   1 
ATOM   4499  C CG1  . VAL B 2 45  ? 123.593 74.217  117.938 1.00 41.95  ?  40  VAL B CG1  1 
ATOM   4500  C CG2  . VAL B 2 45  ? 125.037 73.294  119.777 1.00 41.95  ?  40  VAL B CG2  1 
ATOM   4501  H H    . VAL B 2 45  ? 127.309 73.027  118.302 1.00 41.95  ?  40  VAL B H    1 
ATOM   4502  H HA   . VAL B 2 45  ? 125.074 71.949  117.487 1.00 41.95  ?  40  VAL B HA   1 
ATOM   4503  H HB   . VAL B 2 45  ? 125.563 74.614  118.313 1.00 41.95  ?  40  VAL B HB   1 
ATOM   4504  H HG11 . VAL B 2 45  ? 123.633 74.775  117.146 1.00 41.95  ?  40  VAL B HG11 1 
ATOM   4505  H HG12 . VAL B 2 45  ? 123.182 74.710  118.665 1.00 41.95  ?  40  VAL B HG12 1 
ATOM   4506  H HG13 . VAL B 2 45  ? 123.081 73.414  117.754 1.00 41.95  ?  40  VAL B HG13 1 
ATOM   4507  H HG21 . VAL B 2 45  ? 125.602 73.872  120.313 1.00 41.95  ?  40  VAL B HG21 1 
ATOM   4508  H HG22 . VAL B 2 45  ? 125.393 72.392  119.775 1.00 41.95  ?  40  VAL B HG22 1 
ATOM   4509  H HG23 . VAL B 2 45  ? 124.135 73.292  120.132 1.00 41.95  ?  40  VAL B HG23 1 
ATOM   4510  N N    . GLY B 2 46  ? 126.519 73.689  115.314 1.00 46.25  ?  41  GLY B N    1 
ATOM   4511  C CA   . GLY B 2 46  ? 126.454 74.186  113.954 1.00 46.25  ?  41  GLY B CA   1 
ATOM   4512  C C    . GLY B 2 46  ? 125.889 75.588  113.880 1.00 46.25  ?  41  GLY B C    1 
ATOM   4513  O O    . GLY B 2 46  ? 126.454 76.521  114.460 1.00 46.25  ?  41  GLY B O    1 
ATOM   4514  H H    . GLY B 2 46  ? 127.303 73.729  115.665 1.00 46.25  ?  41  GLY B H    1 
ATOM   4515  H HA2  . GLY B 2 46  ? 127.345 74.193  113.571 1.00 46.25  ?  41  GLY B HA2  1 
ATOM   4516  H HA3  . GLY B 2 46  ? 125.894 73.600  113.421 1.00 46.25  ?  41  GLY B HA3  1 
ATOM   4517  N N    . ARG B 2 47  ? 124.776 75.752  113.169 1.00 45.05  ?  42  ARG B N    1 
ATOM   4518  C CA   . ARG B 2 47  ? 124.124 77.046  113.034 1.00 45.05  ?  42  ARG B CA   1 
ATOM   4519  C C    . ARG B 2 47  ? 122.623 76.876  113.203 1.00 45.05  ?  42  ARG B C    1 
ATOM   4520  O O    . ARG B 2 47  ? 122.014 76.005  112.577 1.00 45.05  ?  42  ARG B O    1 
ATOM   4521  C CB   . ARG B 2 47  ? 124.428 77.687  111.673 1.00 45.05  ?  42  ARG B CB   1 
ATOM   4522  C CG   . ARG B 2 47  ? 124.082 79.166  111.596 1.00 45.05  ?  42  ARG B CG   1 
ATOM   4523  C CD   . ARG B 2 47  ? 123.438 79.520  110.266 1.00 45.05  ?  42  ARG B CD   1 
ATOM   4524  N NE   . ARG B 2 47  ? 124.316 79.220  109.135 1.00 45.05  ?  42  ARG B NE   1 
ATOM   4525  C CZ   . ARG B 2 47  ? 124.128 78.236  108.258 1.00 45.05  ?  42  ARG B CZ   1 
ATOM   4526  N NH1  . ARG B 2 47  ? 124.997 78.064  107.271 1.00 45.05  1  42  ARG B NH1  1 
ATOM   4527  N NH2  . ARG B 2 47  ? 123.086 77.419  108.356 1.00 45.05  ?  42  ARG B NH2  1 
ATOM   4528  H H    . ARG B 2 47  ? 124.374 75.117  112.750 1.00 45.05  ?  42  ARG B H    1 
ATOM   4529  H HA   . ARG B 2 47  ? 124.442 77.642  113.729 1.00 45.05  ?  42  ARG B HA   1 
ATOM   4530  H HB2  . ARG B 2 47  ? 125.375 77.594  111.489 1.00 45.05  ?  42  ARG B HB2  1 
ATOM   4531  H HB3  . ARG B 2 47  ? 123.914 77.227  110.991 1.00 45.05  ?  42  ARG B HB3  1 
ATOM   4532  H HG2  . ARG B 2 47  ? 123.458 79.386  112.305 1.00 45.05  ?  42  ARG B HG2  1 
ATOM   4533  H HG3  . ARG B 2 47  ? 124.894 79.689  111.689 1.00 45.05  ?  42  ARG B HG3  1 
ATOM   4534  H HD2  . ARG B 2 47  ? 122.608 79.030  110.174 1.00 45.05  ?  42  ARG B HD2  1 
ATOM   4535  H HD3  . ARG B 2 47  ? 123.256 80.473  110.253 1.00 45.05  ?  42  ARG B HD3  1 
ATOM   4536  H HE   . ARG B 2 47  ? 125.010 79.718  109.030 1.00 45.05  ?  42  ARG B HE   1 
ATOM   4537  H HH11 . ARG B 2 47  ? 125.676 78.588  107.200 1.00 45.05  ?  42  ARG B HH11 1 
ATOM   4538  H HH12 . ARG B 2 47  ? 124.882 77.430  106.702 1.00 45.05  ?  42  ARG B HH12 1 
ATOM   4539  H HH21 . ARG B 2 47  ? 122.512 77.513  108.987 1.00 45.05  ?  42  ARG B HH21 1 
ATOM   4540  H HH22 . ARG B 2 47  ? 122.984 76.789  107.779 1.00 45.05  ?  42  ARG B HH22 1 
ATOM   4541  N N    . ILE B 2 48  ? 122.035 77.714  114.054 1.00 38.65  ?  43  ILE B N    1 
ATOM   4542  C CA   . ILE B 2 48  ? 120.595 77.743  114.274 1.00 38.65  ?  43  ILE B CA   1 
ATOM   4543  C C    . ILE B 2 48  ? 120.105 79.161  114.021 1.00 38.65  ?  43  ILE B C    1 
ATOM   4544  O O    . ILE B 2 48  ? 120.657 80.125  114.562 1.00 38.65  ?  43  ILE B O    1 
ATOM   4545  C CB   . ILE B 2 48  ? 120.222 77.275  115.698 1.00 38.65  ?  43  ILE B CB   1 
ATOM   4546  C CG1  . ILE B 2 48  ? 121.010 78.059  116.752 1.00 38.65  ?  43  ILE B CG1  1 
ATOM   4547  C CG2  . ILE B 2 48  ? 120.475 75.781  115.844 1.00 38.65  ?  43  ILE B CG2  1 
ATOM   4548  C CD1  . ILE B 2 48  ? 120.646 77.701  118.178 1.00 38.65  ?  43  ILE B CD1  1 
ATOM   4549  H H    . ILE B 2 48  ? 122.464 78.290  114.527 1.00 38.65  ?  43  ILE B H    1 
ATOM   4550  H HA   . ILE B 2 48  ? 120.160 77.154  113.638 1.00 38.65  ?  43  ILE B HA   1 
ATOM   4551  H HB   . ILE B 2 48  ? 119.276 77.440  115.837 1.00 38.65  ?  43  ILE B HB   1 
ATOM   4552  H HG12 . ILE B 2 48  ? 121.956 77.879  116.635 1.00 38.65  ?  43  ILE B HG12 1 
ATOM   4553  H HG13 . ILE B 2 48  ? 120.838 79.005  116.637 1.00 38.65  ?  43  ILE B HG13 1 
ATOM   4554  H HG21 . ILE B 2 48  ? 120.093 75.474  116.681 1.00 38.65  ?  43  ILE B HG21 1 
ATOM   4555  H HG22 . ILE B 2 48  ? 120.058 75.317  115.102 1.00 38.65  ?  43  ILE B HG22 1 
ATOM   4556  H HG23 . ILE B 2 48  ? 121.432 75.622  115.837 1.00 38.65  ?  43  ILE B HG23 1 
ATOM   4557  H HD11 . ILE B 2 48  ? 121.080 78.326  118.780 1.00 38.65  ?  43  ILE B HD11 1 
ATOM   4558  H HD12 . ILE B 2 48  ? 119.683 77.757  118.281 1.00 38.65  ?  43  ILE B HD12 1 
ATOM   4559  H HD13 . ILE B 2 48  ? 120.946 76.798  118.365 1.00 38.65  ?  43  ILE B HD13 1 
ATOM   4560  N N    . GLN B 2 49  ? 119.072 79.287  113.190 1.00 39.88  ?  44  GLN B N    1 
ATOM   4561  C CA   . GLN B 2 49  ? 118.541 80.584  112.774 1.00 39.88  ?  44  GLN B CA   1 
ATOM   4562  C C    . GLN B 2 49  ? 117.112 80.708  113.294 1.00 39.88  ?  44  GLN B C    1 
ATOM   4563  O O    . GLN B 2 49  ? 116.182 80.139  112.715 1.00 39.88  ?  44  GLN B O    1 
ATOM   4564  C CB   . GLN B 2 49  ? 118.592 80.739  111.257 1.00 39.88  ?  44  GLN B CB   1 
ATOM   4565  C CG   . GLN B 2 49  ? 119.922 80.343  110.633 1.00 39.88  ?  44  GLN B CG   1 
ATOM   4566  C CD   . GLN B 2 49  ? 119.883 80.368  109.118 1.00 39.88  ?  44  GLN B CD   1 
ATOM   4567  O OE1  . GLN B 2 49  ? 119.622 81.406  108.509 1.00 39.88  ?  44  GLN B OE1  1 
ATOM   4568  N NE2  . GLN B 2 49  ? 120.143 79.222  108.500 1.00 39.88  ?  44  GLN B NE2  1 
ATOM   4569  H H    . GLN B 2 49  ? 118.651 78.619  112.846 1.00 39.88  ?  44  GLN B H    1 
ATOM   4570  H HA   . GLN B 2 49  ? 119.071 81.293  113.170 1.00 39.88  ?  44  GLN B HA   1 
ATOM   4571  H HB2  . GLN B 2 49  ? 117.904 80.180  110.863 1.00 39.88  ?  44  GLN B HB2  1 
ATOM   4572  H HB3  . GLN B 2 49  ? 118.426 81.668  111.033 1.00 39.88  ?  44  GLN B HB3  1 
ATOM   4573  H HG2  . GLN B 2 49  ? 120.607 80.964  110.927 1.00 39.88  ?  44  GLN B HG2  1 
ATOM   4574  H HG3  . GLN B 2 49  ? 120.149 79.442  110.909 1.00 39.88  ?  44  GLN B HG3  1 
ATOM   4575  H HE21 . GLN B 2 49  ? 120.321 78.517  108.958 1.00 39.88  ?  44  GLN B HE21 1 
ATOM   4576  H HE22 . GLN B 2 49  ? 120.133 79.185  107.640 1.00 39.88  ?  44  GLN B HE22 1 
ATOM   4577  N N    . MET B 2 50  ? 116.943 81.452  114.382 1.00 29.81  ?  45  MET B N    1 
ATOM   4578  C CA   . MET B 2 50  ? 115.622 81.690  114.940 1.00 29.81  ?  45  MET B CA   1 
ATOM   4579  C C    . MET B 2 50  ? 114.938 82.838  114.206 1.00 29.81  ?  45  MET B C    1 
ATOM   4580  O O    . MET B 2 50  ? 115.592 83.716  113.635 1.00 29.81  ?  45  MET B O    1 
ATOM   4581  C CB   . MET B 2 50  ? 115.721 82.010  116.432 1.00 29.81  ?  45  MET B CB   1 
ATOM   4582  C CG   . MET B 2 50  ? 116.378 80.914  117.257 1.00 29.81  ?  45  MET B CG   1 
ATOM   4583  S SD   . MET B 2 50  ? 116.863 81.473  118.901 1.00 29.81  ?  45  MET B SD   1 
ATOM   4584  C CE   . MET B 2 50  ? 116.936 79.915  119.779 1.00 29.81  ?  45  MET B CE   1 
ATOM   4585  H H    . MET B 2 50  ? 117.581 81.832  114.816 1.00 29.81  ?  45  MET B H    1 
ATOM   4586  H HA   . MET B 2 50  ? 115.087 80.887  114.840 1.00 29.81  ?  45  MET B HA   1 
ATOM   4587  H HB2  . MET B 2 50  ? 116.244 82.819  116.544 1.00 29.81  ?  45  MET B HB2  1 
ATOM   4588  H HB3  . MET B 2 50  ? 114.826 82.147  116.781 1.00 29.81  ?  45  MET B HB3  1 
ATOM   4589  H HG2  . MET B 2 50  ? 115.752 80.181  117.364 1.00 29.81  ?  45  MET B HG2  1 
ATOM   4590  H HG3  . MET B 2 50  ? 117.175 80.604  116.799 1.00 29.81  ?  45  MET B HG3  1 
ATOM   4591  H HE1  . MET B 2 50  ? 116.965 80.089  120.733 1.00 29.81  ?  45  MET B HE1  1 
ATOM   4592  H HE2  . MET B 2 50  ? 116.148 79.394  119.560 1.00 29.81  ?  45  MET B HE2  1 
ATOM   4593  H HE3  . MET B 2 50  ? 117.734 79.436  119.504 1.00 29.81  ?  45  MET B HE3  1 
ATOM   4594  N N    . ARG B 2 51  ? 113.608 82.821  114.224 1.00 27.63  ?  46  ARG B N    1 
ATOM   4595  C CA   . ARG B 2 51  ? 112.804 83.831  113.553 1.00 27.63  ?  46  ARG B CA   1 
ATOM   4596  C C    . ARG B 2 51  ? 111.793 84.415  114.529 1.00 27.63  ?  46  ARG B C    1 
ATOM   4597  O O    . ARG B 2 51  ? 111.343 83.742  115.460 1.00 27.63  ?  46  ARG B O    1 
ATOM   4598  C CB   . ARG B 2 51  ? 112.074 83.250  112.335 1.00 27.63  ?  46  ARG B CB   1 
ATOM   4599  C CG   . ARG B 2 51  ? 112.899 83.264  111.058 1.00 27.63  ?  46  ARG B CG   1 
ATOM   4600  C CD   . ARG B 2 51  ? 112.351 82.283  110.031 1.00 27.63  ?  46  ARG B CD   1 
ATOM   4601  N NE   . ARG B 2 51  ? 110.911 82.431  109.836 1.00 27.63  ?  46  ARG B NE   1 
ATOM   4602  C CZ   . ARG B 2 51  ? 110.331 83.486  109.271 1.00 27.63  ?  46  ARG B CZ   1 
ATOM   4603  N NH1  . ARG B 2 51  ? 109.013 83.526  109.141 1.00 27.63  1  46  ARG B NH1  1 
ATOM   4604  N NH2  . ARG B 2 51  ? 111.064 84.500  108.827 1.00 27.63  ?  46  ARG B NH2  1 
ATOM   4605  H H    . ARG B 2 51  ? 113.141 82.222  114.627 1.00 27.63  ?  46  ARG B H    1 
ATOM   4606  H HA   . ARG B 2 51  ? 113.378 84.550  113.247 1.00 27.63  ?  46  ARG B HA   1 
ATOM   4607  H HB2  . ARG B 2 51  ? 111.837 82.328  112.524 1.00 27.63  ?  46  ARG B HB2  1 
ATOM   4608  H HB3  . ARG B 2 51  ? 111.271 83.770  112.175 1.00 27.63  ?  46  ARG B HB3  1 
ATOM   4609  H HG2  . ARG B 2 51  ? 112.880 84.154  110.676 1.00 27.63  ?  46  ARG B HG2  1 
ATOM   4610  H HG3  . ARG B 2 51  ? 113.811 83.008  111.265 1.00 27.63  ?  46  ARG B HG3  1 
ATOM   4611  H HD2  . ARG B 2 51  ? 112.789 82.438  109.180 1.00 27.63  ?  46  ARG B HD2  1 
ATOM   4612  H HD3  . ARG B 2 51  ? 112.523 81.378  110.334 1.00 27.63  ?  46  ARG B HD3  1 
ATOM   4613  H HE   . ARG B 2 51  ? 110.404 81.784  110.090 1.00 27.63  ?  46  ARG B HE   1 
ATOM   4614  H HH11 . ARG B 2 51  ? 108.533 82.871  109.425 1.00 27.63  ?  46  ARG B HH11 1 
ATOM   4615  H HH12 . ARG B 2 51  ? 108.637 84.206  108.773 1.00 27.63  ?  46  ARG B HH12 1 
ATOM   4616  H HH21 . ARG B 2 51  ? 111.920 84.484  108.905 1.00 27.63  ?  46  ARG B HH21 1 
ATOM   4617  H HH22 . ARG B 2 51  ? 110.680 85.177  108.461 1.00 27.63  ?  46  ARG B HH22 1 
ATOM   4618  N N    . THR B 2 52  ? 111.442 85.678  114.304 1.00 24.01  ?  47  THR B N    1 
ATOM   4619  C CA   . THR B 2 52  ? 110.475 86.369  115.152 1.00 24.01  ?  47  THR B CA   1 
ATOM   4620  C C    . THR B 2 52  ? 109.081 85.821  114.875 1.00 24.01  ?  47  THR B C    1 
ATOM   4621  O O    . THR B 2 52  ? 108.521 86.043  113.796 1.00 24.01  ?  47  THR B O    1 
ATOM   4622  C CB   . THR B 2 52  ? 110.529 87.872  114.897 1.00 24.01  ?  47  THR B CB   1 
ATOM   4623  O OG1  . THR B 2 52  ? 111.768 88.400  115.386 1.00 24.01  ?  47  THR B OG1  1 
ATOM   4624  C CG2  . THR B 2 52  ? 109.372 88.578  115.591 1.00 24.01  ?  47  THR B CG2  1 
ATOM   4625  H H    . THR B 2 52  ? 111.751 86.160  113.662 1.00 24.01  ?  47  THR B H    1 
ATOM   4626  H HA   . THR B 2 52  ? 110.690 86.207  116.084 1.00 24.01  ?  47  THR B HA   1 
ATOM   4627  H HB   . THR B 2 52  ? 110.462 88.040  113.944 1.00 24.01  ?  47  THR B HB   1 
ATOM   4628  H HG1  . THR B 2 52  ? 112.410 88.060  114.965 1.00 24.01  ?  47  THR B HG1  1 
ATOM   4629  H HG21 . THR B 2 52  ? 109.556 89.528  115.658 1.00 24.01  ?  47  THR B HG21 1 
ATOM   4630  H HG22 . THR B 2 52  ? 109.251 88.217  116.483 1.00 24.01  ?  47  THR B HG22 1 
ATOM   4631  H HG23 . THR B 2 52  ? 108.553 88.452  115.087 1.00 24.01  ?  47  THR B HG23 1 
ATOM   4632  N N    . ARG B 2 53  ? 108.517 85.103  115.846 1.00 28.02  ?  48  ARG B N    1 
ATOM   4633  C CA   . ARG B 2 53  ? 107.184 84.537  115.699 1.00 28.02  ?  48  ARG B CA   1 
ATOM   4634  C C    . ARG B 2 53  ? 106.082 85.482  116.155 1.00 28.02  ?  48  ARG B C    1 
ATOM   4635  O O    . ARG B 2 53  ? 104.986 85.451  115.584 1.00 28.02  ?  48  ARG B O    1 
ATOM   4636  C CB   . ARG B 2 53  ? 107.078 83.226  116.487 1.00 28.02  ?  48  ARG B CB   1 
ATOM   4637  C CG   . ARG B 2 53  ? 108.167 82.211  116.167 1.00 28.02  ?  48  ARG B CG   1 
ATOM   4638  C CD   . ARG B 2 53  ? 108.139 81.788  114.706 1.00 28.02  ?  48  ARG B CD   1 
ATOM   4639  N NE   . ARG B 2 53  ? 109.213 80.851  114.387 1.00 28.02  ?  48  ARG B NE   1 
ATOM   4640  C CZ   . ARG B 2 53  ? 109.346 80.232  113.218 1.00 28.02  ?  48  ARG B CZ   1 
ATOM   4641  N NH1  . ARG B 2 53  ? 110.356 79.396  113.022 1.00 28.02  1  48  ARG B NH1  1 
ATOM   4642  N NH2  . ARG B 2 53  ? 108.473 80.448  112.242 1.00 28.02  ?  48  ARG B NH2  1 
ATOM   4643  H H    . ARG B 2 53  ? 108.890 84.932  116.602 1.00 28.02  ?  48  ARG B H    1 
ATOM   4644  H HA   . ARG B 2 53  ? 107.030 84.336  114.763 1.00 28.02  ?  48  ARG B HA   1 
ATOM   4645  H HB2  . ARG B 2 53  ? 107.131 83.428  117.434 1.00 28.02  ?  48  ARG B HB2  1 
ATOM   4646  H HB3  . ARG B 2 53  ? 106.223 82.813  116.288 1.00 28.02  ?  48  ARG B HB3  1 
ATOM   4647  H HG2  . ARG B 2 53  ? 109.035 82.602  116.354 1.00 28.02  ?  48  ARG B HG2  1 
ATOM   4648  H HG3  . ARG B 2 53  ? 108.033 81.420  116.713 1.00 28.02  ?  48  ARG B HG3  1 
ATOM   4649  H HD2  . ARG B 2 53  ? 107.293 81.355  114.515 1.00 28.02  ?  48  ARG B HD2  1 
ATOM   4650  H HD3  . ARG B 2 53  ? 108.250 82.570  114.143 1.00 28.02  ?  48  ARG B HD3  1 
ATOM   4651  H HE   . ARG B 2 53  ? 109.814 80.712  114.986 1.00 28.02  ?  48  ARG B HE   1 
ATOM   4652  H HH11 . ARG B 2 53  ? 110.925 79.254  113.652 1.00 28.02  ?  48  ARG B HH11 1 
ATOM   4653  H HH12 . ARG B 2 53  ? 110.443 78.996  112.266 1.00 28.02  ?  48  ARG B HH12 1 
ATOM   4654  H HH21 . ARG B 2 53  ? 107.815 80.988  112.361 1.00 28.02  ?  48  ARG B HH21 1 
ATOM   4655  H HH22 . ARG B 2 53  ? 108.565 80.045  111.488 1.00 28.02  ?  48  ARG B HH22 1 
ATOM   4656  N N    . ARG B 2 54  ? 106.343 86.315  117.161 1.00 26.50  ?  49  ARG B N    1 
ATOM   4657  C CA   . ARG B 2 54  ? 105.350 87.254  117.659 1.00 26.50  ?  49  ARG B CA   1 
ATOM   4658  C C    . ARG B 2 54  ? 106.022 88.590  117.936 1.00 26.50  ?  49  ARG B C    1 
ATOM   4659  O O    . ARG B 2 54  ? 107.193 88.644  118.321 1.00 26.50  ?  49  ARG B O    1 
ATOM   4660  C CB   . ARG B 2 54  ? 104.669 86.738  118.933 1.00 26.50  ?  49  ARG B CB   1 
ATOM   4661  C CG   . ARG B 2 54  ? 104.003 85.378  118.785 1.00 26.50  ?  49  ARG B CG   1 
ATOM   4662  C CD   . ARG B 2 54  ? 102.729 85.464  117.961 1.00 26.50  ?  49  ARG B CD   1 
ATOM   4663  N NE   . ARG B 2 54  ? 101.915 84.256  118.085 1.00 26.50  ?  49  ARG B NE   1 
ATOM   4664  C CZ   . ARG B 2 54  ? 101.880 83.266  117.197 1.00 26.50  ?  49  ARG B CZ   1 
ATOM   4665  N NH1  . ARG B 2 54  ? 101.100 82.216  117.414 1.00 26.50  1  49  ARG B NH1  1 
ATOM   4666  N NH2  . ARG B 2 54  ? 102.620 83.311  116.095 1.00 26.50  ?  49  ARG B NH2  1 
ATOM   4667  H H    . ARG B 2 54  ? 107.096 86.353  117.574 1.00 26.50  ?  49  ARG B H    1 
ATOM   4668  H HA   . ARG B 2 54  ? 104.668 87.393  116.983 1.00 26.50  ?  49  ARG B HA   1 
ATOM   4669  H HB2  . ARG B 2 54  ? 105.336 86.664  119.632 1.00 26.50  ?  49  ARG B HB2  1 
ATOM   4670  H HB3  . ARG B 2 54  ? 103.986 87.373  119.199 1.00 26.50  ?  49  ARG B HB3  1 
ATOM   4671  H HG2  . ARG B 2 54  ? 104.612 84.766  118.342 1.00 26.50  ?  49  ARG B HG2  1 
ATOM   4672  H HG3  . ARG B 2 54  ? 103.772 85.040  119.664 1.00 26.50  ?  49  ARG B HG3  1 
ATOM   4673  H HD2  . ARG B 2 54  ? 102.200 86.210  118.284 1.00 26.50  ?  49  ARG B HD2  1 
ATOM   4674  H HD3  . ARG B 2 54  ? 102.956 85.604  117.030 1.00 26.50  ?  49  ARG B HD3  1 
ATOM   4675  H HE   . ARG B 2 54  ? 101.414 84.184  118.781 1.00 26.50  ?  49  ARG B HE   1 
ATOM   4676  H HH11 . ARG B 2 54  ? 100.618 82.178  118.126 1.00 26.50  ?  49  ARG B HH11 1 
ATOM   4677  H HH12 . ARG B 2 54  ? 101.075 81.573  116.844 1.00 26.50  ?  49  ARG B HH12 1 
ATOM   4678  H HH21 . ARG B 2 54  ? 103.131 83.984  115.939 1.00 26.50  ?  49  ARG B HH21 1 
ATOM   4679  H HH22 . ARG B 2 54  ? 102.586 82.662  115.532 1.00 26.50  ?  49  ARG B HH22 1 
ATOM   4680  N N    . THR B 2 55  ? 105.267 89.666  117.734 1.00 24.06  ?  50  THR B N    1 
ATOM   4681  C CA   . THR B 2 55  ? 105.711 91.019  118.040 1.00 24.06  ?  50  THR B CA   1 
ATOM   4682  C C    . THR B 2 55  ? 104.660 91.691  118.910 1.00 24.06  ?  50  THR B C    1 
ATOM   4683  O O    . THR B 2 55  ? 103.475 91.703  118.559 1.00 24.06  ?  50  THR B O    1 
ATOM   4684  C CB   . THR B 2 55  ? 105.945 91.832  116.763 1.00 24.06  ?  50  THR B CB   1 
ATOM   4685  O OG1  . THR B 2 55  ? 106.916 91.170  115.942 1.00 24.06  ?  50  THR B OG1  1 
ATOM   4686  C CG2  . THR B 2 55  ? 106.442 93.232  117.100 1.00 24.06  ?  50  THR B CG2  1 
ATOM   4687  H H    . THR B 2 55  ? 104.471 89.635  117.410 1.00 24.06  ?  50  THR B H    1 
ATOM   4688  H HA   . THR B 2 55  ? 106.543 90.984  118.537 1.00 24.06  ?  50  THR B HA   1 
ATOM   4689  H HB   . THR B 2 55  ? 105.111 91.913  116.274 1.00 24.06  ?  50  THR B HB   1 
ATOM   4690  H HG1  . THR B 2 55  ? 106.643 90.403  115.736 1.00 24.06  ?  50  THR B HG1  1 
ATOM   4691  H HG21 . THR B 2 55  ? 106.748 93.676  116.294 1.00 24.06  ?  50  THR B HG21 1 
ATOM   4692  H HG22 . THR B 2 55  ? 105.727 93.755  117.494 1.00 24.06  ?  50  THR B HG22 1 
ATOM   4693  H HG23 . THR B 2 55  ? 107.179 93.179  117.728 1.00 24.06  ?  50  THR B HG23 1 
ATOM   4694  N N    . LEU B 2 56  ? 105.093 92.247  120.038 1.00 23.14  ?  51  LEU B N    1 
ATOM   4695  C CA   . LEU B 2 56  ? 104.202 92.868  121.010 1.00 23.14  ?  51  LEU B CA   1 
ATOM   4696  C C    . LEU B 2 56  ? 104.371 94.379  120.936 1.00 23.14  ?  51  LEU B C    1 
ATOM   4697  O O    . LEU B 2 56  ? 105.498 94.885  120.991 1.00 23.14  ?  51  LEU B O    1 
ATOM   4698  C CB   . LEU B 2 56  ? 104.499 92.360  122.421 1.00 23.14  ?  51  LEU B CB   1 
ATOM   4699  C CG   . LEU B 2 56  ? 104.598 90.839  122.569 1.00 23.14  ?  51  LEU B CG   1 
ATOM   4700  C CD1  . LEU B 2 56  ? 104.897 90.456  124.009 1.00 23.14  ?  51  LEU B CD1  1 
ATOM   4701  C CD2  . LEU B 2 56  ? 103.326 90.161  122.087 1.00 23.14  ?  51  LEU B CD2  1 
ATOM   4702  H H    . LEU B 2 56  ? 105.921 92.276  120.267 1.00 23.14  ?  51  LEU B H    1 
ATOM   4703  H HA   . LEU B 2 56  ? 103.282 92.651  120.793 1.00 23.14  ?  51  LEU B HA   1 
ATOM   4704  H HB2  . LEU B 2 56  ? 105.343 92.738  122.711 1.00 23.14  ?  51  LEU B HB2  1 
ATOM   4705  H HB3  . LEU B 2 56  ? 103.791 92.663  123.010 1.00 23.14  ?  51  LEU B HB3  1 
ATOM   4706  H HG   . LEU B 2 56  ? 105.331 90.518  122.020 1.00 23.14  ?  51  LEU B HG   1 
ATOM   4707  H HD11 . LEU B 2 56  ? 105.735 90.864  124.277 1.00 23.14  ?  51  LEU B HD11 1 
ATOM   4708  H HD12 . LEU B 2 56  ? 104.964 89.490  124.071 1.00 23.14  ?  51  LEU B HD12 1 
ATOM   4709  H HD13 . LEU B 2 56  ? 104.177 90.774  124.576 1.00 23.14  ?  51  LEU B HD13 1 
ATOM   4710  H HD21 . LEU B 2 56  ? 103.248 90.282  121.128 1.00 23.14  ?  51  LEU B HD21 1 
ATOM   4711  H HD22 . LEU B 2 56  ? 102.565 90.562  122.536 1.00 23.14  ?  51  LEU B HD22 1 
ATOM   4712  H HD23 . LEU B 2 56  ? 103.375 89.215  122.297 1.00 23.14  ?  51  LEU B HD23 1 
ATOM   4713  N N    . ARG B 2 57  ? 103.255 95.094  120.813 1.00 25.21  ?  52  ARG B N    1 
ATOM   4714  C CA   . ARG B 2 57  ? 103.249 96.546  120.714 1.00 25.21  ?  52  ARG B CA   1 
ATOM   4715  C C    . ARG B 2 57  ? 102.228 97.122  121.684 1.00 25.21  ?  52  ARG B C    1 
ATOM   4716  O O    . ARG B 2 57  ? 101.221 96.478  121.996 1.00 25.21  ?  52  ARG B O    1 
ATOM   4717  C CB   . ARG B 2 57  ? 102.924 97.003  119.288 1.00 25.21  ?  52  ARG B CB   1 
ATOM   4718  C CG   . ARG B 2 57  ? 103.777 96.347  118.214 1.00 25.21  ?  52  ARG B CG   1 
ATOM   4719  C CD   . ARG B 2 57  ? 103.491 96.940  116.844 1.00 25.21  ?  52  ARG B CD   1 
ATOM   4720  N NE   . ARG B 2 57  ? 103.991 96.095  115.763 1.00 25.21  ?  52  ARG B NE   1 
ATOM   4721  C CZ   . ARG B 2 57  ? 105.255 96.069  115.350 1.00 25.21  ?  52  ARG B CZ   1 
ATOM   4722  N NH1  . ARG B 2 57  ? 105.610 95.265  114.358 1.00 25.21  1  52  ARG B NH1  1 
ATOM   4723  N NH2  . ARG B 2 57  ? 106.166 96.843  115.927 1.00 25.21  ?  52  ARG B NH2  1 
ATOM   4724  H H    . ARG B 2 57  ? 102.469 94.747  120.785 1.00 25.21  ?  52  ARG B H    1 
ATOM   4725  H HA   . ARG B 2 57  ? 104.124 96.890  120.953 1.00 25.21  ?  52  ARG B HA   1 
ATOM   4726  H HB2  . ARG B 2 57  ? 101.996 96.792  119.097 1.00 25.21  ?  52  ARG B HB2  1 
ATOM   4727  H HB3  . ARG B 2 57  ? 103.061 97.961  119.229 1.00 25.21  ?  52  ARG B HB3  1 
ATOM   4728  H HG2  . ARG B 2 57  ? 104.714 96.490  118.418 1.00 25.21  ?  52  ARG B HG2  1 
ATOM   4729  H HG3  . ARG B 2 57  ? 103.579 95.398  118.182 1.00 25.21  ?  52  ARG B HG3  1 
ATOM   4730  H HD2  . ARG B 2 57  ? 102.531 97.032  116.733 1.00 25.21  ?  52  ARG B HD2  1 
ATOM   4731  H HD3  . ARG B 2 57  ? 103.917 97.809  116.776 1.00 25.21  ?  52  ARG B HD3  1 
ATOM   4732  H HE   . ARG B 2 57  ? 103.430 95.577  115.367 1.00 25.21  ?  52  ARG B HE   1 
ATOM   4733  H HH11 . ARG B 2 57  ? 105.024 94.762  113.981 1.00 25.21  ?  52  ARG B HH11 1 
ATOM   4734  H HH12 . ARG B 2 57  ? 106.428 95.247  114.091 1.00 25.21  ?  52  ARG B HH12 1 
ATOM   4735  H HH21 . ARG B 2 57  ? 105.946 97.367  116.571 1.00 25.21  ?  52  ARG B HH21 1 
ATOM   4736  H HH22 . ARG B 2 57  ? 106.982 96.819  115.654 1.00 25.21  ?  52  ARG B HH22 1 
ATOM   4737  N N    . GLY B 2 58  ? 102.485 98.344  122.144 1.00 24.69  ?  53  GLY B N    1 
ATOM   4738  C CA   . GLY B 2 58  ? 101.597 99.008  123.078 1.00 24.69  ?  53  GLY B CA   1 
ATOM   4739  C C    . GLY B 2 58  ? 102.332 99.821  124.123 1.00 24.69  ?  53  GLY B C    1 
ATOM   4740  O O    . GLY B 2 58  ? 101.786 100.788 124.661 1.00 24.69  ?  53  GLY B O    1 
ATOM   4741  H H    . GLY B 2 58  ? 103.176 98.809  121.927 1.00 24.69  ?  53  GLY B H    1 
ATOM   4742  H HA2  . GLY B 2 58  ? 101.006 99.603  122.590 1.00 24.69  ?  53  GLY B HA2  1 
ATOM   4743  H HA3  . GLY B 2 58  ? 101.055 98.346  123.534 1.00 24.69  ?  53  GLY B HA3  1 
ATOM   4744  N N    . HIS B 2 59  ? 103.571 99.440  124.422 1.00 22.29  ?  54  HIS B N    1 
ATOM   4745  C CA   . HIS B 2 59  ? 104.385 100.214 125.349 1.00 22.29  ?  54  HIS B CA   1 
ATOM   4746  C C    . HIS B 2 59  ? 104.823 101.521 124.702 1.00 22.29  ?  54  HIS B C    1 
ATOM   4747  O O    . HIS B 2 59  ? 105.116 101.574 123.504 1.00 22.29  ?  54  HIS B O    1 
ATOM   4748  C CB   . HIS B 2 59  ? 105.604 99.405  125.789 1.00 22.29  ?  54  HIS B CB   1 
ATOM   4749  C CG   . HIS B 2 59  ? 105.312 98.416  126.874 1.00 22.29  ?  54  HIS B CG   1 
ATOM   4750  N ND1  . HIS B 2 59  ? 104.902 98.795  128.134 1.00 22.29  ?  54  HIS B ND1  1 
ATOM   4751  C CD2  . HIS B 2 59  ? 105.365 97.063  126.887 1.00 22.29  ?  54  HIS B CD2  1 
ATOM   4752  C CE1  . HIS B 2 59  ? 104.720 97.718  128.878 1.00 22.29  ?  54  HIS B CE1  1 
ATOM   4753  N NE2  . HIS B 2 59  ? 104.994 96.654  128.145 1.00 22.29  ?  54  HIS B NE2  1 
ATOM   4754  H H    . HIS B 2 59  ? 103.960 98.742  124.104 1.00 22.29  ?  54  HIS B H    1 
ATOM   4755  H HA   . HIS B 2 59  ? 103.860 100.425 126.136 1.00 22.29  ?  54  HIS B HA   1 
ATOM   4756  H HB2  . HIS B 2 59  ? 105.946 98.916  125.025 1.00 22.29  ?  54  HIS B HB2  1 
ATOM   4757  H HB3  . HIS B 2 59  ? 106.282 100.016 126.118 1.00 22.29  ?  54  HIS B HB3  1 
ATOM   4758  H HD2  . HIS B 2 59  ? 105.610 96.514  126.178 1.00 22.29  ?  54  HIS B HD2  1 
ATOM   4759  H HE1  . HIS B 2 59  ? 104.444 97.710  129.766 1.00 22.29  ?  54  HIS B HE1  1 
ATOM   4760  H HE2  . HIS B 2 59  ? 104.947 95.838  128.411 1.00 22.29  ?  54  HIS B HE2  1 
ATOM   4761  N N    . LEU B 2 60  ? 104.867 102.584 125.505 1.00 25.50  ?  55  LEU B N    1 
ATOM   4762  C CA   . LEU B 2 60  ? 105.195 103.911 125.000 1.00 25.50  ?  55  LEU B CA   1 
ATOM   4763  C C    . LEU B 2 60  ? 106.683 104.223 125.100 1.00 25.50  ?  55  LEU B C    1 
ATOM   4764  O O    . LEU B 2 60  ? 107.289 104.661 124.115 1.00 25.50  ?  55  LEU B O    1 
ATOM   4765  C CB   . LEU B 2 60  ? 104.396 104.973 125.759 1.00 25.50  ?  55  LEU B CB   1 
ATOM   4766  C CG   . LEU B 2 60  ? 102.903 104.687 125.934 1.00 25.50  ?  55  LEU B CG   1 
ATOM   4767  C CD1  . LEU B 2 60  ? 102.227 105.825 126.681 1.00 25.50  ?  55  LEU B CD1  1 
ATOM   4768  C CD2  . LEU B 2 60  ? 102.237 104.455 124.586 1.00 25.50  ?  55  LEU B CD2  1 
ATOM   4769  H H    . LEU B 2 60  ? 104.711 102.560 126.351 1.00 25.50  ?  55  LEU B H    1 
ATOM   4770  H HA   . LEU B 2 60  ? 104.944 103.962 124.064 1.00 25.50  ?  55  LEU B HA   1 
ATOM   4771  H HB2  . LEU B 2 60  ? 104.778 105.067 126.646 1.00 25.50  ?  55  LEU B HB2  1 
ATOM   4772  H HB3  . LEU B 2 60  ? 104.476 105.814 125.283 1.00 25.50  ?  55  LEU B HB3  1 
ATOM   4773  H HG   . LEU B 2 60  ? 102.797 103.880 126.462 1.00 25.50  ?  55  LEU B HG   1 
ATOM   4774  H HD11 . LEU B 2 60  ? 102.588 105.870 127.581 1.00 25.50  ?  55  LEU B HD11 1 
ATOM   4775  H HD12 . LEU B 2 60  ? 101.272 105.657 126.715 1.00 25.50  ?  55  LEU B HD12 1 
ATOM   4776  H HD13 . LEU B 2 60  ? 102.401 106.656 126.213 1.00 25.50  ?  55  LEU B HD13 1 
ATOM   4777  H HD21 . LEU B 2 60  ? 102.561 103.621 124.213 1.00 25.50  ?  55  LEU B HD21 1 
ATOM   4778  H HD22 . LEU B 2 60  ? 102.457 105.191 123.994 1.00 25.50  ?  55  LEU B HD22 1 
ATOM   4779  H HD23 . LEU B 2 60  ? 101.276 104.408 124.714 1.00 25.50  ?  55  LEU B HD23 1 
ATOM   4780  N N    . ALA B 2 61  ? 107.285 104.009 126.265 1.00 21.77  ?  56  ALA B N    1 
ATOM   4781  C CA   . ALA B 2 61  ? 108.684 104.324 126.493 1.00 21.77  ?  56  ALA B CA   1 
ATOM   4782  C C    . ALA B 2 61  ? 109.527 103.055 126.394 1.00 21.77  ?  56  ALA B C    1 
ATOM   4783  O O    . ALA B 2 61  ? 109.026 101.964 126.103 1.00 21.77  ?  56  ALA B O    1 
ATOM   4784  C CB   . ALA B 2 61  ? 108.852 105.009 127.850 1.00 21.77  ?  56  ALA B CB   1 
ATOM   4785  H H    . ALA B 2 61  ? 106.892 103.673 126.953 1.00 21.77  ?  56  ALA B H    1 
ATOM   4786  H HA   . ALA B 2 61  ? 108.988 104.940 125.808 1.00 21.77  ?  56  ALA B HA   1 
ATOM   4787  H HB1  . ALA B 2 61  ? 109.786 105.242 127.972 1.00 21.77  ?  56  ALA B HB1  1 
ATOM   4788  H HB2  . ALA B 2 61  ? 108.569 104.399 128.549 1.00 21.77  ?  56  ALA B HB2  1 
ATOM   4789  H HB3  . ALA B 2 61  ? 108.307 105.811 127.867 1.00 21.77  ?  56  ALA B HB3  1 
ATOM   4790  N N    . LYS B 2 62  ? 110.827 103.196 126.641 1.00 20.05  ?  57  LYS B N    1 
ATOM   4791  C CA   . LYS B 2 62  ? 111.738 102.064 126.542 1.00 20.05  ?  57  LYS B CA   1 
ATOM   4792  C C    . LYS B 2 62  ? 111.399 101.004 127.584 1.00 20.05  ?  57  LYS B C    1 
ATOM   4793  O O    . LYS B 2 62  ? 111.139 101.317 128.749 1.00 20.05  ?  57  LYS B O    1 
ATOM   4794  C CB   . LYS B 2 62  ? 113.184 102.535 126.714 1.00 20.05  ?  57  LYS B CB   1 
ATOM   4795  C CG   . LYS B 2 62  ? 113.433 103.394 127.946 1.00 20.05  ?  57  LYS B CG   1 
ATOM   4796  C CD   . LYS B 2 62  ? 114.892 103.807 128.039 1.00 20.05  ?  57  LYS B CD   1 
ATOM   4797  C CE   . LYS B 2 62  ? 115.179 104.550 129.332 1.00 20.05  ?  57  LYS B CE   1 
ATOM   4798  N NZ   . LYS B 2 62  ? 114.596 105.919 129.331 1.00 20.05  1  57  LYS B NZ   1 
ATOM   4799  H H    . LYS B 2 62  ? 111.200 103.937 126.862 1.00 20.05  ?  57  LYS B H    1 
ATOM   4800  H HA   . LYS B 2 62  ? 111.653 101.662 125.664 1.00 20.05  ?  57  LYS B HA   1 
ATOM   4801  H HB2  . LYS B 2 62  ? 113.757 101.757 126.786 1.00 20.05  ?  57  LYS B HB2  1 
ATOM   4802  H HB3  . LYS B 2 62  ? 113.435 103.057 125.936 1.00 20.05  ?  57  LYS B HB3  1 
ATOM   4803  H HG2  . LYS B 2 62  ? 112.896 104.199 127.897 1.00 20.05  ?  57  LYS B HG2  1 
ATOM   4804  H HG3  . LYS B 2 62  ? 113.208 102.886 128.742 1.00 20.05  ?  57  LYS B HG3  1 
ATOM   4805  H HD2  . LYS B 2 62  ? 115.451 103.015 128.013 1.00 20.05  ?  57  LYS B HD2  1 
ATOM   4806  H HD3  . LYS B 2 62  ? 115.107 104.394 127.297 1.00 20.05  ?  57  LYS B HD3  1 
ATOM   4807  H HE2  . LYS B 2 62  ? 114.791 104.058 130.071 1.00 20.05  ?  57  LYS B HE2  1 
ATOM   4808  H HE3  . LYS B 2 62  ? 116.139 104.629 129.449 1.00 20.05  ?  57  LYS B HE3  1 
ATOM   4809  H HZ1  . LYS B 2 62  ? 114.941 106.396 128.664 1.00 20.05  ?  57  LYS B HZ1  1 
ATOM   4810  H HZ2  . LYS B 2 62  ? 114.775 106.327 130.101 1.00 20.05  ?  57  LYS B HZ2  1 
ATOM   4811  H HZ3  . LYS B 2 62  ? 113.713 105.873 129.227 1.00 20.05  ?  57  LYS B HZ3  1 
ATOM   4812  N N    . ILE B 2 63  ? 111.403 99.746  127.153 1.00 19.18  ?  58  ILE B N    1 
ATOM   4813  C CA   . ILE B 2 63  ? 111.133 98.618  128.038 1.00 19.18  ?  58  ILE B CA   1 
ATOM   4814  C C    . ILE B 2 63  ? 112.458 98.137  128.613 1.00 19.18  ?  58  ILE B C    1 
ATOM   4815  O O    . ILE B 2 63  ? 113.435 97.961  127.878 1.00 19.18  ?  58  ILE B O    1 
ATOM   4816  C CB   . ILE B 2 63  ? 110.412 97.490  127.287 1.00 19.18  ?  58  ILE B CB   1 
ATOM   4817  C CG1  . ILE B 2 63  ? 109.064 97.986  126.760 1.00 19.18  ?  58  ILE B CG1  1 
ATOM   4818  C CG2  . ILE B 2 63  ? 110.216 96.280  128.193 1.00 19.18  ?  58  ILE B CG2  1 
ATOM   4819  C CD1  . ILE B 2 63  ? 108.409 97.043  125.783 1.00 19.18  ?  58  ILE B CD1  1 
ATOM   4820  H H    . ILE B 2 63  ? 111.563 99.517  126.340 1.00 19.18  ?  58  ILE B H    1 
ATOM   4821  H HA   . ILE B 2 63  ? 110.567 98.908  128.770 1.00 19.18  ?  58  ILE B HA   1 
ATOM   4822  H HB   . ILE B 2 63  ? 110.959 97.223  126.532 1.00 19.18  ?  58  ILE B HB   1 
ATOM   4823  H HG12 . ILE B 2 63  ? 108.460 98.097  127.510 1.00 19.18  ?  58  ILE B HG12 1 
ATOM   4824  H HG13 . ILE B 2 63  ? 109.192 98.836  126.312 1.00 19.18  ?  58  ILE B HG13 1 
ATOM   4825  H HG21 . ILE B 2 63  ? 111.078 95.878  128.380 1.00 19.18  ?  58  ILE B HG21 1 
ATOM   4826  H HG22 . ILE B 2 63  ? 109.799 96.570  129.019 1.00 19.18  ?  58  ILE B HG22 1 
ATOM   4827  H HG23 . ILE B 2 63  ? 109.647 95.637  127.744 1.00 19.18  ?  58  ILE B HG23 1 
ATOM   4828  H HD11 . ILE B 2 63  ? 107.742 97.530  125.275 1.00 19.18  ?  58  ILE B HD11 1 
ATOM   4829  H HD12 . ILE B 2 63  ? 107.988 96.324  126.278 1.00 19.18  ?  58  ILE B HD12 1 
ATOM   4830  H HD13 . ILE B 2 63  ? 109.085 96.687  125.185 1.00 19.18  ?  58  ILE B HD13 1 
ATOM   4831  N N    . TYR B 2 64  ? 112.497 97.924  129.928 1.00 20.26  ?  59  TYR B N    1 
ATOM   4832  C CA   . TYR B 2 64  ? 113.743 97.587  130.604 1.00 20.26  ?  59  TYR B CA   1 
ATOM   4833  C C    . TYR B 2 64  ? 113.804 96.146  131.092 1.00 20.26  ?  59  TYR B C    1 
ATOM   4834  O O    . TYR B 2 64  ? 114.881 95.542  131.052 1.00 20.26  ?  59  TYR B O    1 
ATOM   4835  C CB   . TYR B 2 64  ? 113.970 98.520  131.798 1.00 20.26  ?  59  TYR B CB   1 
ATOM   4836  C CG   . TYR B 2 64  ? 115.271 98.260  132.523 1.00 20.26  ?  59  TYR B CG   1 
ATOM   4837  C CD1  . TYR B 2 64  ? 116.481 98.679  131.984 1.00 20.26  ?  59  TYR B CD1  1 
ATOM   4838  C CD2  . TYR B 2 64  ? 115.294 97.588  133.735 1.00 20.26  ?  59  TYR B CD2  1 
ATOM   4839  C CE1  . TYR B 2 64  ? 117.675 98.443  132.637 1.00 20.26  ?  59  TYR B CE1  1 
ATOM   4840  C CE2  . TYR B 2 64  ? 116.486 97.346  134.395 1.00 20.26  ?  59  TYR B CE2  1 
ATOM   4841  C CZ   . TYR B 2 64  ? 117.672 97.776  133.842 1.00 20.26  ?  59  TYR B CZ   1 
ATOM   4842  O OH   . TYR B 2 64  ? 118.857 97.536  134.498 1.00 20.26  ?  59  TYR B OH   1 
ATOM   4843  H H    . TYR B 2 64  ? 111.814 97.970  130.450 1.00 20.26  ?  59  TYR B H    1 
ATOM   4844  H HA   . TYR B 2 64  ? 114.479 97.720  129.988 1.00 20.26  ?  59  TYR B HA   1 
ATOM   4845  H HB2  . TYR B 2 64  ? 113.982 99.437  131.483 1.00 20.26  ?  59  TYR B HB2  1 
ATOM   4846  H HB3  . TYR B 2 64  ? 113.246 98.399  132.433 1.00 20.26  ?  59  TYR B HB3  1 
ATOM   4847  H HD1  . TYR B 2 64  ? 116.486 99.131  131.171 1.00 20.26  ?  59  TYR B HD1  1 
ATOM   4848  H HD2  . TYR B 2 64  ? 114.495 97.296  134.112 1.00 20.26  ?  59  TYR B HD2  1 
ATOM   4849  H HE1  . TYR B 2 64  ? 118.477 98.732  132.265 1.00 20.26  ?  59  TYR B HE1  1 
ATOM   4850  H HE2  . TYR B 2 64  ? 116.486 96.896  135.209 1.00 20.26  ?  59  TYR B HE2  1 
ATOM   4851  H HH   . TYR B 2 64  ? 118.712 97.114  135.209 1.00 20.26  ?  59  TYR B HH   1 
ATOM   4852  N N    . ALA B 2 65  ? 112.691 95.578  131.553 1.00 18.05  ?  60  ALA B N    1 
ATOM   4853  C CA   . ALA B 2 65  ? 112.712 94.241  132.131 1.00 18.05  ?  60  ALA B CA   1 
ATOM   4854  C C    . ALA B 2 65  ? 111.429 93.502  131.780 1.00 18.05  ?  60  ALA B C    1 
ATOM   4855  O O    . ALA B 2 65  ? 110.389 94.108  131.513 1.00 18.05  ?  60  ALA B O    1 
ATOM   4856  C CB   . ALA B 2 65  ? 112.891 94.294  133.653 1.00 18.05  ?  60  ALA B CB   1 
ATOM   4857  H H    . ALA B 2 65  ? 111.913 95.946  131.542 1.00 18.05  ?  60  ALA B H    1 
ATOM   4858  H HA   . ALA B 2 65  ? 113.456 93.743  131.760 1.00 18.05  ?  60  ALA B HA   1 
ATOM   4859  H HB1  . ALA B 2 65  ? 112.902 93.389  134.001 1.00 18.05  ?  60  ALA B HB1  1 
ATOM   4860  H HB2  . ALA B 2 65  ? 112.152 94.789  134.040 1.00 18.05  ?  60  ALA B HB2  1 
ATOM   4861  H HB3  . ALA B 2 65  ? 113.730 94.738  133.856 1.00 18.05  ?  60  ALA B HB3  1 
ATOM   4862  N N    . MET B 2 66  ? 111.523 92.172  131.788 1.00 19.08  ?  61  MET B N    1 
ATOM   4863  C CA   . MET B 2 66  ? 110.380 91.297  131.568 1.00 19.08  ?  61  MET B CA   1 
ATOM   4864  C C    . MET B 2 66  ? 110.658 89.955  132.229 1.00 19.08  ?  61  MET B C    1 
ATOM   4865  O O    . MET B 2 66  ? 111.803 89.636  132.557 1.00 19.08  ?  61  MET B O    1 
ATOM   4866  C CB   . MET B 2 66  ? 110.086 91.111  130.068 1.00 19.08  ?  61  MET B CB   1 
ATOM   4867  C CG   . MET B 2 66  ? 111.209 90.469  129.258 1.00 19.08  ?  61  MET B CG   1 
ATOM   4868  S SD   . MET B 2 66  ? 111.386 88.688  129.493 1.00 19.08  ?  61  MET B SD   1 
ATOM   4869  C CE   . MET B 2 66  ? 110.037 88.081  128.484 1.00 19.08  ?  61  MET B CE   1 
ATOM   4870  H H    . MET B 2 66  ? 112.258 91.746  131.922 1.00 19.08  ?  61  MET B H    1 
ATOM   4871  H HA   . MET B 2 66  ? 109.597 91.696  131.977 1.00 19.08  ?  61  MET B HA   1 
ATOM   4872  H HB2  . MET B 2 66  ? 109.301 90.548  129.977 1.00 19.08  ?  61  MET B HB2  1 
ATOM   4873  H HB3  . MET B 2 66  ? 109.907 91.982  129.680 1.00 19.08  ?  61  MET B HB3  1 
ATOM   4874  H HG2  . MET B 2 66  ? 111.046 90.629  128.315 1.00 19.08  ?  61  MET B HG2  1 
ATOM   4875  H HG3  . MET B 2 66  ? 112.048 90.876  129.521 1.00 19.08  ?  61  MET B HG3  1 
ATOM   4876  H HE1  . MET B 2 66  ? 109.199 88.410  128.846 1.00 19.08  ?  61  MET B HE1  1 
ATOM   4877  H HE2  . MET B 2 66  ? 110.044 87.112  128.497 1.00 19.08  ?  61  MET B HE2  1 
ATOM   4878  H HE3  . MET B 2 66  ? 110.153 88.401  127.576 1.00 19.08  ?  61  MET B HE3  1 
ATOM   4879  N N    . HIS B 2 67  ? 109.599 89.170  132.422 1.00 20.22  ?  62  HIS B N    1 
ATOM   4880  C CA   . HIS B 2 67  ? 109.728 87.861  133.050 1.00 20.22  ?  62  HIS B CA   1 
ATOM   4881  C C    . HIS B 2 67  ? 108.700 86.911  132.458 1.00 20.22  ?  62  HIS B C    1 
ATOM   4882  O O    . HIS B 2 67  ? 107.531 87.277  132.302 1.00 20.22  ?  62  HIS B O    1 
ATOM   4883  C CB   . HIS B 2 67  ? 109.545 87.960  134.570 1.00 20.22  ?  62  HIS B CB   1 
ATOM   4884  C CG   . HIS B 2 67  ? 110.151 86.820  135.328 1.00 20.22  ?  62  HIS B CG   1 
ATOM   4885  N ND1  . HIS B 2 67  ? 109.585 86.307  136.476 1.00 20.22  ?  62  HIS B ND1  1 
ATOM   4886  C CD2  . HIS B 2 67  ? 111.272 86.094  135.105 1.00 20.22  ?  62  HIS B CD2  1 
ATOM   4887  C CE1  . HIS B 2 67  ? 110.331 85.314  136.926 1.00 20.22  ?  62  HIS B CE1  1 
ATOM   4888  N NE2  . HIS B 2 67  ? 111.360 85.164  136.113 1.00 20.22  ?  62  HIS B NE2  1 
ATOM   4889  H H    . HIS B 2 67  ? 108.795 89.375  132.198 1.00 20.22  ?  62  HIS B H    1 
ATOM   4890  H HA   . HIS B 2 67  ? 110.612 87.506  132.868 1.00 20.22  ?  62  HIS B HA   1 
ATOM   4891  H HB2  . HIS B 2 67  ? 109.962 88.778  134.882 1.00 20.22  ?  62  HIS B HB2  1 
ATOM   4892  H HB3  . HIS B 2 67  ? 108.596 87.978  134.769 1.00 20.22  ?  62  HIS B HB3  1 
ATOM   4893  H HD2  . HIS B 2 67  ? 111.870 86.204  134.401 1.00 20.22  ?  62  HIS B HD2  1 
ATOM   4894  H HE1  . HIS B 2 67  ? 110.160 84.807  137.687 1.00 20.22  ?  62  HIS B HE1  1 
ATOM   4895  H HE2  . HIS B 2 67  ? 111.985 84.580  136.200 1.00 20.22  ?  62  HIS B HE2  1 
ATOM   4896  N N    . TRP B 2 68  ? 109.139 85.697  132.135 1.00 21.89  ?  63  TRP B N    1 
ATOM   4897  C CA   . TRP B 2 68  ? 108.240 84.670  131.627 1.00 21.89  ?  63  TRP B CA   1 
ATOM   4898  C C    . TRP B 2 68  ? 107.471 84.015  132.765 1.00 21.89  ?  63  TRP B C    1 
ATOM   4899  O O    . TRP B 2 68  ? 107.965 83.910  133.892 1.00 21.89  ?  63  TRP B O    1 
ATOM   4900  C CB   . TRP B 2 68  ? 109.019 83.603  130.859 1.00 21.89  ?  63  TRP B CB   1 
ATOM   4901  C CG   . TRP B 2 68  ? 109.218 83.918  129.413 1.00 21.89  ?  63  TRP B CG   1 
ATOM   4902  C CD1  . TRP B 2 68  ? 110.364 84.355  128.818 1.00 21.89  ?  63  TRP B CD1  1 
ATOM   4903  C CD2  . TRP B 2 68  ? 108.239 83.817  128.373 1.00 21.89  ?  63  TRP B CD2  1 
ATOM   4904  N NE1  . TRP B 2 68  ? 110.161 84.532  127.471 1.00 21.89  ?  63  TRP B NE1  1 
ATOM   4905  C CE2  . TRP B 2 68  ? 108.863 84.209  127.172 1.00 21.89  ?  63  TRP B CE2  1 
ATOM   4906  C CE3  . TRP B 2 68  ? 106.895 83.434  128.340 1.00 21.89  ?  63  TRP B CE3  1 
ATOM   4907  C CZ2  . TRP B 2 68  ? 108.190 84.228  125.953 1.00 21.89  ?  63  TRP B CZ2  1 
ATOM   4908  C CZ3  . TRP B 2 68  ? 106.229 83.453  127.129 1.00 21.89  ?  63  TRP B CZ3  1 
ATOM   4909  C CH2  . TRP B 2 68  ? 106.876 83.848  125.953 1.00 21.89  ?  63  TRP B CH2  1 
ATOM   4910  H H    . TRP B 2 68  ? 109.958 85.444  132.201 1.00 21.89  ?  63  TRP B H    1 
ATOM   4911  H HA   . TRP B 2 68  ? 107.600 85.075  131.021 1.00 21.89  ?  63  TRP B HA   1 
ATOM   4912  H HB2  . TRP B 2 68  ? 109.895 83.503  131.263 1.00 21.89  ?  63  TRP B HB2  1 
ATOM   4913  H HB3  . TRP B 2 68  ? 108.535 82.764  130.914 1.00 21.89  ?  63  TRP B HB3  1 
ATOM   4914  H HD1  . TRP B 2 68  ? 111.168 84.509  129.260 1.00 21.89  ?  63  TRP B HD1  1 
ATOM   4915  H HE1  . TRP B 2 68  ? 110.751 84.802  126.907 1.00 21.89  ?  63  TRP B HE1  1 
ATOM   4916  H HE3  . TRP B 2 68  ? 106.458 83.170  129.117 1.00 21.89  ?  63  TRP B HE3  1 
ATOM   4917  H HZ2  . TRP B 2 68  ? 108.616 84.489  125.170 1.00 21.89  ?  63  TRP B HZ2  1 
ATOM   4918  H HZ3  . TRP B 2 68  ? 105.334 83.200  127.095 1.00 21.89  ?  63  TRP B HZ3  1 
ATOM   4919  H HH2  . TRP B 2 68  ? 106.403 83.852  125.152 1.00 21.89  ?  63  TRP B HH2  1 
ATOM   4920  N N    . GLY B 2 69  ? 106.253 83.572  132.462 1.00 25.43  ?  64  GLY B N    1 
ATOM   4921  C CA   . GLY B 2 69  ? 105.472 82.845  133.437 1.00 25.43  ?  64  GLY B CA   1 
ATOM   4922  C C    . GLY B 2 69  ? 105.894 81.393  133.548 1.00 25.43  ?  64  GLY B C    1 
ATOM   4923  O O    . GLY B 2 69  ? 106.526 80.823  132.659 1.00 25.43  ?  64  GLY B O    1 
ATOM   4924  H H    . GLY B 2 69  ? 105.865 83.682  131.703 1.00 25.43  ?  64  GLY B H    1 
ATOM   4925  H HA2  . GLY B 2 69  ? 105.582 83.259  134.305 1.00 25.43  ?  64  GLY B HA2  1 
ATOM   4926  H HA3  . GLY B 2 69  ? 104.533 82.878  133.194 1.00 25.43  ?  64  GLY B HA3  1 
ATOM   4927  N N    . THR B 2 70  ? 105.529 80.783  134.678 1.00 29.10  ?  65  THR B N    1 
ATOM   4928  C CA   . THR B 2 70  ? 105.835 79.373  134.890 1.00 29.10  ?  65  THR B CA   1 
ATOM   4929  C C    . THR B 2 70  ? 105.087 78.471  133.918 1.00 29.10  ?  65  THR B C    1 
ATOM   4930  O O    . THR B 2 70  ? 105.578 77.384  133.598 1.00 29.10  ?  65  THR B O    1 
ATOM   4931  C CB   . THR B 2 70  ? 105.502 78.968  136.326 1.00 29.10  ?  65  THR B CB   1 
ATOM   4932  O OG1  . THR B 2 70  ? 104.204 79.464  136.678 1.00 29.10  ?  65  THR B OG1  1 
ATOM   4933  C CG2  . THR B 2 70  ? 106.537 79.524  137.293 1.00 29.10  ?  65  THR B CG2  1 
ATOM   4934  H H    . THR B 2 70  ? 105.109 81.159  135.327 1.00 29.10  ?  65  THR B H    1 
ATOM   4935  H HA   . THR B 2 70  ? 106.785 79.234  134.753 1.00 29.10  ?  65  THR B HA   1 
ATOM   4936  H HB   . THR B 2 70  ? 105.506 78.001  136.397 1.00 29.10  ?  65  THR B HB   1 
ATOM   4937  H HG1  . THR B 2 70  ? 104.019 79.249  137.469 1.00 29.10  ?  65  THR B HG1  1 
ATOM   4938  H HG21 . THR B 2 70  ? 106.347 79.218  138.193 1.00 29.10  ?  65  THR B HG21 1 
ATOM   4939  H HG22 . THR B 2 70  ? 106.518 80.494  137.278 1.00 29.10  ?  65  THR B HG22 1 
ATOM   4940  H HG23 . THR B 2 70  ? 107.423 79.222  137.039 1.00 29.10  ?  65  THR B HG23 1 
ATOM   4941  N N    . ASP B 2 71  ? 103.917 78.896  133.444 1.00 29.61  ?  66  ASP B N    1 
ATOM   4942  C CA   . ASP B 2 71  ? 103.158 78.131  132.463 1.00 29.61  ?  66  ASP B CA   1 
ATOM   4943  C C    . ASP B 2 71  ? 103.603 78.399  131.031 1.00 29.61  ?  66  ASP B C    1 
ATOM   4944  O O    . ASP B 2 71  ? 103.076 77.768  130.109 1.00 29.61  ?  66  ASP B O    1 
ATOM   4945  C CB   . ASP B 2 71  ? 101.662 78.438  132.603 1.00 29.61  ?  66  ASP B CB   1 
ATOM   4946  C CG   . ASP B 2 71  ? 101.342 79.909  132.398 1.00 29.61  ?  66  ASP B CG   1 
ATOM   4947  O OD1  . ASP B 2 71  ? 102.229 80.662  131.944 1.00 29.61  ?  66  ASP B OD1  1 
ATOM   4948  O OD2  . ASP B 2 71  ? 100.197 80.312  132.692 1.00 29.61  -1 66  ASP B OD2  1 
ATOM   4949  H H    . ASP B 2 71  ? 103.540 79.631  133.680 1.00 29.61  ?  66  ASP B H    1 
ATOM   4950  H HA   . ASP B 2 71  ? 103.283 77.186  132.639 1.00 29.61  ?  66  ASP B HA   1 
ATOM   4951  H HB2  . ASP B 2 71  ? 101.172 77.929  131.938 1.00 29.61  ?  66  ASP B HB2  1 
ATOM   4952  H HB3  . ASP B 2 71  ? 101.371 78.188  133.494 1.00 29.61  ?  66  ASP B HB3  1 
ATOM   4953  N N    . SER B 2 72  ? 104.549 79.312  130.824 1.00 28.57  ?  67  SER B N    1 
ATOM   4954  C CA   . SER B 2 72  ? 105.063 79.674  129.507 1.00 28.57  ?  67  SER B CA   1 
ATOM   4955  C C    . SER B 2 72  ? 103.984 80.243  128.594 1.00 28.57  ?  67  SER B C    1 
ATOM   4956  O O    . SER B 2 72  ? 104.126 80.191  127.367 1.00 28.57  ?  67  SER B O    1 
ATOM   4957  C CB   . SER B 2 72  ? 105.739 78.477  128.828 1.00 28.57  ?  67  SER B CB   1 
ATOM   4958  O OG   . SER B 2 72  ? 106.850 78.031  129.586 1.00 28.57  ?  67  SER B OG   1 
ATOM   4959  H H    . SER B 2 72  ? 104.924 79.755  131.459 1.00 28.57  ?  67  SER B H    1 
ATOM   4960  H HA   . SER B 2 72  ? 105.737 80.362  129.621 1.00 28.57  ?  67  SER B HA   1 
ATOM   4961  H HB2  . SER B 2 72  ? 105.099 77.753  128.748 1.00 28.57  ?  67  SER B HB2  1 
ATOM   4962  H HB3  . SER B 2 72  ? 106.047 78.746  127.948 1.00 28.57  ?  67  SER B HB3  1 
ATOM   4963  H HG   . SER B 2 72  ? 107.196 77.359  129.221 1.00 28.57  ?  67  SER B HG   1 
ATOM   4964  N N    . ARG B 2 73  ? 102.910 80.787  129.162 1.00 27.77  ?  68  ARG B N    1 
ATOM   4965  C CA   . ARG B 2 73  ? 101.832 81.399  128.395 1.00 27.77  ?  68  ARG B CA   1 
ATOM   4966  C C    . ARG B 2 73  ? 101.734 82.895  128.642 1.00 27.77  ?  68  ARG B C    1 
ATOM   4967  O O    . ARG B 2 73  ? 101.664 83.674  127.684 1.00 27.77  ?  68  ARG B O    1 
ATOM   4968  C CB   . ARG B 2 73  ? 100.496 80.717  128.739 1.00 27.77  ?  68  ARG B CB   1 
ATOM   4969  C CG   . ARG B 2 73  ? 99.277  81.312  128.042 1.00 27.77  ?  68  ARG B CG   1 
ATOM   4970  C CD   . ARG B 2 73  ? 99.259  80.966  126.565 1.00 27.77  ?  68  ARG B CD   1 
ATOM   4971  N NE   . ARG B 2 73  ? 98.056  81.459  125.899 1.00 27.77  ?  68  ARG B NE   1 
ATOM   4972  C CZ   . ARG B 2 73  ? 96.874  80.852  125.932 1.00 27.77  ?  68  ARG B CZ   1 
ATOM   4973  N NH1  . ARG B 2 73  ? 95.840  81.382  125.293 1.00 27.77  1  68  ARG B NH1  1 
ATOM   4974  N NH2  . ARG B 2 73  ? 96.719  79.717  126.602 1.00 27.77  ?  68  ARG B NH2  1 
ATOM   4975  H H    . ARG B 2 73  ? 102.781 80.814  130.012 1.00 27.77  ?  68  ARG B H    1 
ATOM   4976  H HA   . ARG B 2 73  ? 101.999 81.265  127.449 1.00 27.77  ?  68  ARG B HA   1 
ATOM   4977  H HB2  . ARG B 2 73  ? 100.551 79.782  128.484 1.00 27.77  ?  68  ARG B HB2  1 
ATOM   4978  H HB3  . ARG B 2 73  ? 100.350 80.786  129.695 1.00 27.77  ?  68  ARG B HB3  1 
ATOM   4979  H HG2  . ARG B 2 73  ? 98.474  80.946  128.445 1.00 27.77  ?  68  ARG B HG2  1 
ATOM   4980  H HG3  . ARG B 2 73  ? 99.279  82.278  128.130 1.00 27.77  ?  68  ARG B HG3  1 
ATOM   4981  H HD2  . ARG B 2 73  ? 100.028 81.371  126.135 1.00 27.77  ?  68  ARG B HD2  1 
ATOM   4982  H HD3  . ARG B 2 73  ? 99.291  80.002  126.464 1.00 27.77  ?  68  ARG B HD3  1 
ATOM   4983  H HE   . ARG B 2 73  ? 98.123  82.181  125.435 1.00 27.77  ?  68  ARG B HE   1 
ATOM   4984  H HH11 . ARG B 2 73  ? 95.935  82.117  124.857 1.00 27.77  ?  68  ARG B HH11 1 
ATOM   4985  H HH12 . ARG B 2 73  ? 95.075  80.990  125.314 1.00 27.77  ?  68  ARG B HH12 1 
ATOM   4986  H HH21 . ARG B 2 73  ? 97.383  79.366  127.020 1.00 27.77  ?  68  ARG B HH21 1 
ATOM   4987  H HH22 . ARG B 2 73  ? 95.951  79.332  126.619 1.00 27.77  ?  68  ARG B HH22 1 
ATOM   4988  N N    . LEU B 2 74  ? 101.731 83.318  129.901 1.00 25.41  ?  69  LEU B N    1 
ATOM   4989  C CA   . LEU B 2 74  ? 101.647 84.728  130.248 1.00 25.41  ?  69  LEU B CA   1 
ATOM   4990  C C    . LEU B 2 74  ? 103.021 85.262  130.632 1.00 25.41  ?  69  LEU B C    1 
ATOM   4991  O O    . LEU B 2 74  ? 103.830 84.566  131.252 1.00 25.41  ?  69  LEU B O    1 
ATOM   4992  C CB   . LEU B 2 74  ? 100.666 84.941  131.402 1.00 25.41  ?  69  LEU B CB   1 
ATOM   4993  C CG   . LEU B 2 74  ? 99.252  84.393  131.194 1.00 25.41  ?  69  LEU B CG   1 
ATOM   4994  C CD1  . LEU B 2 74  ? 98.353  84.784  132.356 1.00 25.41  ?  69  LEU B CD1  1 
ATOM   4995  C CD2  . LEU B 2 74  ? 98.666  84.878  129.876 1.00 25.41  ?  69  LEU B CD2  1 
ATOM   4996  H H    . LEU B 2 74  ? 101.777 82.797  130.584 1.00 25.41  ?  69  LEU B H    1 
ATOM   4997  H HA   . LEU B 2 74  ? 101.331 85.232  129.482 1.00 25.41  ?  69  LEU B HA   1 
ATOM   4998  H HB2  . LEU B 2 74  ? 101.029 84.511  132.193 1.00 25.41  ?  69  LEU B HB2  1 
ATOM   4999  H HB3  . LEU B 2 74  ? 100.586 85.894  131.563 1.00 25.41  ?  69  LEU B HB3  1 
ATOM   5000  H HG   . LEU B 2 74  ? 99.293  83.424  131.162 1.00 25.41  ?  69  LEU B HG   1 
ATOM   5001  H HD11 . LEU B 2 74  ? 98.722  84.420  133.175 1.00 25.41  ?  69  LEU B HD11 1 
ATOM   5002  H HD12 . LEU B 2 74  ? 97.466  84.425  132.202 1.00 25.41  ?  69  LEU B HD12 1 
ATOM   5003  H HD13 . LEU B 2 74  ? 98.314  85.752  132.412 1.00 25.41  ?  69  LEU B HD13 1 
ATOM   5004  H HD21 . LEU B 2 74  ? 99.150  84.465  129.143 1.00 25.41  ?  69  LEU B HD21 1 
ATOM   5005  H HD22 . LEU B 2 74  ? 98.753  85.843  129.828 1.00 25.41  ?  69  LEU B HD22 1 
ATOM   5006  H HD23 . LEU B 2 74  ? 97.730  84.626  129.836 1.00 25.41  ?  69  LEU B HD23 1 
ATOM   5007  N N    . LEU B 2 75  ? 103.278 86.511  130.252 1.00 21.57  ?  70  LEU B N    1 
ATOM   5008  C CA   . LEU B 2 75  ? 104.532 87.170  130.580 1.00 21.57  ?  70  LEU B CA   1 
ATOM   5009  C C    . LEU B 2 75  ? 104.245 88.620  130.936 1.00 21.57  ?  70  LEU B C    1 
ATOM   5010  O O    . LEU B 2 75  ? 103.265 89.207  130.470 1.00 21.57  ?  70  LEU B O    1 
ATOM   5011  C CB   . LEU B 2 75  ? 105.535 87.087  129.421 1.00 21.57  ?  70  LEU B CB   1 
ATOM   5012  C CG   . LEU B 2 75  ? 105.159 87.807  128.122 1.00 21.57  ?  70  LEU B CG   1 
ATOM   5013  C CD1  . LEU B 2 75  ? 105.657 89.248  128.113 1.00 21.57  ?  70  LEU B CD1  1 
ATOM   5014  C CD2  . LEU B 2 75  ? 105.700 87.047  126.920 1.00 21.57  ?  70  LEU B CD2  1 
ATOM   5015  H H    . LEU B 2 75  ? 102.735 87.001  129.799 1.00 21.57  ?  70  LEU B H    1 
ATOM   5016  H HA   . LEU B 2 75  ? 104.928 86.741  131.355 1.00 21.57  ?  70  LEU B HA   1 
ATOM   5017  H HB2  . LEU B 2 75  ? 106.377 87.461  129.724 1.00 21.57  ?  70  LEU B HB2  1 
ATOM   5018  H HB3  . LEU B 2 75  ? 105.663 86.151  129.201 1.00 21.57  ?  70  LEU B HB3  1 
ATOM   5019  H HG   . LEU B 2 75  ? 104.192 87.828  128.046 1.00 21.57  ?  70  LEU B HG   1 
ATOM   5020  H HD11 . LEU B 2 75  ? 105.112 89.780  128.713 1.00 21.57  ?  70  LEU B HD11 1 
ATOM   5021  H HD12 . LEU B 2 75  ? 105.588 89.597  127.211 1.00 21.57  ?  70  LEU B HD12 1 
ATOM   5022  H HD13 . LEU B 2 75  ? 106.583 89.266  128.401 1.00 21.57  ?  70  LEU B HD13 1 
ATOM   5023  H HD21 . LEU B 2 75  ? 106.664 86.970  127.004 1.00 21.57  ?  70  LEU B HD21 1 
ATOM   5024  H HD22 . LEU B 2 75  ? 105.476 87.534  126.112 1.00 21.57  ?  70  LEU B HD22 1 
ATOM   5025  H HD23 . LEU B 2 75  ? 105.298 86.165  126.897 1.00 21.57  ?  70  LEU B HD23 1 
ATOM   5026  N N    . VAL B 2 76  ? 105.112 89.190  131.768 1.00 21.32  ?  71  VAL B N    1 
ATOM   5027  C CA   . VAL B 2 76  ? 104.977 90.567  132.225 1.00 21.32  ?  71  VAL B CA   1 
ATOM   5028  C C    . VAL B 2 76  ? 106.217 91.343  131.806 1.00 21.32  ?  71  VAL B C    1 
ATOM   5029  O O    . VAL B 2 76  ? 107.349 90.862  131.926 1.00 21.32  ?  71  VAL B O    1 
ATOM   5030  C CB   . VAL B 2 76  ? 104.770 90.643  133.753 1.00 21.32  ?  71  VAL B CB   1 
ATOM   5031  C CG1  . VAL B 2 76  ? 106.022 90.182  134.490 1.00 21.32  ?  71  VAL B CG1  1 
ATOM   5032  C CG2  . VAL B 2 76  ? 104.384 92.056  134.170 1.00 21.32  ?  71  VAL B CG2  1 
ATOM   5033  H H    . VAL B 2 76  ? 105.802 88.789  132.088 1.00 21.32  ?  71  VAL B H    1 
ATOM   5034  H HA   . VAL B 2 76  ? 104.208 90.973  131.796 1.00 21.32  ?  71  VAL B HA   1 
ATOM   5035  H HB   . VAL B 2 76  ? 104.043 90.050  134.001 1.00 21.32  ?  71  VAL B HB   1 
ATOM   5036  H HG11 . VAL B 2 76  ? 106.323 89.344  134.106 1.00 21.32  ?  71  VAL B HG11 1 
ATOM   5037  H HG12 . VAL B 2 76  ? 105.806 90.056  135.427 1.00 21.32  ?  71  VAL B HG12 1 
ATOM   5038  H HG13 . VAL B 2 76  ? 106.714 90.855  134.398 1.00 21.32  ?  71  VAL B HG13 1 
ATOM   5039  H HG21 . VAL B 2 76  ? 104.322 92.615  133.379 1.00 21.32  ?  71  VAL B HG21 1 
ATOM   5040  H HG22 . VAL B 2 76  ? 103.526 92.026  134.621 1.00 21.32  ?  71  VAL B HG22 1 
ATOM   5041  H HG23 . VAL B 2 76  ? 105.061 92.405  134.770 1.00 21.32  ?  71  VAL B HG23 1 
ATOM   5042  N N    . SER B 2 77  ? 105.993 92.556  131.306 1.00 19.48  ?  72  SER B N    1 
ATOM   5043  C CA   . SER B 2 77  ? 107.070 93.439  130.885 1.00 19.48  ?  72  SER B CA   1 
ATOM   5044  C C    . SER B 2 77  ? 106.842 94.818  131.484 1.00 19.48  ?  72  SER B C    1 
ATOM   5045  O O    . SER B 2 77  ? 105.708 95.299  131.558 1.00 19.48  ?  72  SER B O    1 
ATOM   5046  C CB   . SER B 2 77  ? 107.157 93.536  129.357 1.00 19.48  ?  72  SER B CB   1 
ATOM   5047  O OG   . SER B 2 77  ? 105.941 94.016  128.811 1.00 19.48  ?  72  SER B OG   1 
ATOM   5048  H H    . SER B 2 77  ? 105.209 92.894  131.199 1.00 19.48  ?  72  SER B H    1 
ATOM   5049  H HA   . SER B 2 77  ? 107.916 93.100  131.217 1.00 19.48  ?  72  SER B HA   1 
ATOM   5050  H HB2  . SER B 2 77  ? 107.872 94.147  129.119 1.00 19.48  ?  72  SER B HB2  1 
ATOM   5051  H HB3  . SER B 2 77  ? 107.339 92.655  128.994 1.00 19.48  ?  72  SER B HB3  1 
ATOM   5052  H HG   . SER B 2 77  ? 105.298 93.575  129.123 1.00 19.48  ?  72  SER B HG   1 
ATOM   5053  N N    . ALA B 2 78  ? 107.933 95.451  131.907 1.00 19.85  ?  73  ALA B N    1 
ATOM   5054  C CA   . ALA B 2 78  ? 107.888 96.748  132.566 1.00 19.85  ?  73  ALA B CA   1 
ATOM   5055  C C    . ALA B 2 78  ? 108.510 97.801  131.662 1.00 19.85  ?  73  ALA B C    1 
ATOM   5056  O O    . ALA B 2 78  ? 109.636 97.630  131.183 1.00 19.85  ?  73  ALA B O    1 
ATOM   5057  C CB   . ALA B 2 78  ? 108.622 96.709  133.909 1.00 19.85  ?  73  ALA B CB   1 
ATOM   5058  H H    . ALA B 2 78  ? 108.729 95.139  131.820 1.00 19.85  ?  73  ALA B H    1 
ATOM   5059  H HA   . ALA B 2 78  ? 106.966 96.997  132.730 1.00 19.85  ?  73  ALA B HA   1 
ATOM   5060  H HB1  . ALA B 2 78  ? 108.601 97.595  134.304 1.00 19.85  ?  73  ALA B HB1  1 
ATOM   5061  H HB2  . ALA B 2 78  ? 108.175 96.077  134.491 1.00 19.85  ?  73  ALA B HB2  1 
ATOM   5062  H HB3  . ALA B 2 78  ? 109.540 96.434  133.759 1.00 19.85  ?  73  ALA B HB3  1 
ATOM   5063  N N    . SER B 2 79  ? 107.775 98.886  131.437 1.00 20.57  ?  74  SER B N    1 
ATOM   5064  C CA   . SER B 2 79  ? 108.243 100.018 130.652 1.00 20.57  ?  74  SER B CA   1 
ATOM   5065  C C    . SER B 2 79  ? 108.319 101.245 131.548 1.00 20.57  ?  74  SER B C    1 
ATOM   5066  O O    . SER B 2 79  ? 107.477 101.432 132.432 1.00 20.57  ?  74  SER B O    1 
ATOM   5067  C CB   . SER B 2 79  ? 107.316 100.289 129.463 1.00 20.57  ?  74  SER B CB   1 
ATOM   5068  O OG   . SER B 2 79  ? 107.688 101.476 128.785 1.00 20.57  ?  74  SER B OG   1 
ATOM   5069  H H    . SER B 2 79  ? 106.977 98.990  131.740 1.00 20.57  ?  74  SER B H    1 
ATOM   5070  H HA   . SER B 2 79  ? 109.131 99.833  130.311 1.00 20.57  ?  74  SER B HA   1 
ATOM   5071  H HB2  . SER B 2 79  ? 107.372 99.544  128.845 1.00 20.57  ?  74  SER B HB2  1 
ATOM   5072  H HB3  . SER B 2 79  ? 106.407 100.380 129.788 1.00 20.57  ?  74  SER B HB3  1 
ATOM   5073  H HG   . SER B 2 79  ? 107.174 101.609 128.135 1.00 20.57  ?  74  SER B HG   1 
ATOM   5074  N N    . GLN B 2 80  ? 109.329 102.077 131.318 1.00 20.91  ?  75  GLN B N    1 
ATOM   5075  C CA   . GLN B 2 80  ? 109.554 103.243 132.169 1.00 20.91  ?  75  GLN B CA   1 
ATOM   5076  C C    . GLN B 2 80  ? 108.568 104.376 131.910 1.00 20.91  ?  75  GLN B C    1 
ATOM   5077  O O    . GLN B 2 80  ? 108.793 105.481 132.422 1.00 20.91  ?  75  GLN B O    1 
ATOM   5078  C CB   . GLN B 2 80  ? 110.989 103.741 131.994 1.00 20.91  ?  75  GLN B CB   1 
ATOM   5079  C CG   . GLN B 2 80  ? 112.036 102.679 132.293 1.00 20.91  ?  75  GLN B CG   1 
ATOM   5080  C CD   . GLN B 2 80  ? 113.265 103.243 132.978 1.00 20.91  ?  75  GLN B CD   1 
ATOM   5081  O OE1  . GLN B 2 80  ? 113.174 103.827 134.057 1.00 20.91  ?  75  GLN B OE1  1 
ATOM   5082  N NE2  . GLN B 2 80  ? 114.425 103.058 132.360 1.00 20.91  ?  75  GLN B NE2  1 
ATOM   5083  H H    . GLN B 2 80  ? 109.897 101.992 130.678 1.00 20.91  ?  75  GLN B H    1 
ATOM   5084  H HA   . GLN B 2 80  ? 109.451 102.970 133.093 1.00 20.91  ?  75  GLN B HA   1 
ATOM   5085  H HB2  . GLN B 2 80  ? 111.111 104.030 131.076 1.00 20.91  ?  75  GLN B HB2  1 
ATOM   5086  H HB3  . GLN B 2 80  ? 111.139 104.486 132.597 1.00 20.91  ?  75  GLN B HB3  1 
ATOM   5087  H HG2  . GLN B 2 80  ? 111.648 102.009 132.877 1.00 20.91  ?  75  GLN B HG2  1 
ATOM   5088  H HG3  . GLN B 2 80  ? 112.317 102.270 131.460 1.00 20.91  ?  75  GLN B HG3  1 
ATOM   5089  H HE21 . GLN B 2 80  ? 114.449 102.642 131.607 1.00 20.91  ?  75  GLN B HE21 1 
ATOM   5090  H HE22 . GLN B 2 80  ? 115.151 103.358 132.709 1.00 20.91  ?  75  GLN B HE22 1 
ATOM   5091  N N    . ASP B 2 81  ? 107.498 104.156 131.145 1.00 23.29  ?  76  ASP B N    1 
ATOM   5092  C CA   . ASP B 2 81  ? 106.446 105.154 131.003 1.00 23.29  ?  76  ASP B CA   1 
ATOM   5093  C C    . ASP B 2 81  ? 105.417 105.083 132.122 1.00 23.29  ?  76  ASP B C    1 
ATOM   5094  O O    . ASP B 2 81  ? 104.479 105.887 132.129 1.00 23.29  ?  76  ASP B O    1 
ATOM   5095  C CB   . ASP B 2 81  ? 105.737 104.989 129.655 1.00 23.29  ?  76  ASP B CB   1 
ATOM   5096  C CG   . ASP B 2 81  ? 104.937 103.705 129.571 1.00 23.29  ?  76  ASP B CG   1 
ATOM   5097  O OD1  . ASP B 2 81  ? 105.525 102.623 129.774 1.00 23.29  ?  76  ASP B OD1  1 
ATOM   5098  O OD2  . ASP B 2 81  ? 103.720 103.778 129.300 1.00 23.29  -1 76  ASP B OD2  1 
ATOM   5099  H H    . ASP B 2 81  ? 107.359 103.436 130.697 1.00 23.29  ?  76  ASP B H    1 
ATOM   5100  H HA   . ASP B 2 81  ? 106.846 106.037 131.021 1.00 23.29  ?  76  ASP B HA   1 
ATOM   5101  H HB2  . ASP B 2 81  ? 105.126 105.731 129.528 1.00 23.29  ?  76  ASP B HB2  1 
ATOM   5102  H HB3  . ASP B 2 81  ? 106.398 104.978 128.947 1.00 23.29  ?  76  ASP B HB3  1 
ATOM   5103  N N    . GLY B 2 82  ? 105.567 104.149 133.059 1.00 24.65  ?  77  GLY B N    1 
ATOM   5104  C CA   . GLY B 2 82  ? 104.621 104.000 134.145 1.00 24.65  ?  77  GLY B CA   1 
ATOM   5105  C C    . GLY B 2 82  ? 103.586 102.918 133.949 1.00 24.65  ?  77  GLY B C    1 
ATOM   5106  O O    . GLY B 2 82  ? 102.606 102.880 134.701 1.00 24.65  ?  77  GLY B O    1 
ATOM   5107  H H    . GLY B 2 82  ? 106.217 103.586 133.083 1.00 24.65  ?  77  GLY B H    1 
ATOM   5108  H HA2  . GLY B 2 82  ? 105.109 103.799 134.959 1.00 24.65  ?  77  GLY B HA2  1 
ATOM   5109  H HA3  . GLY B 2 82  ? 104.154 104.840 134.277 1.00 24.65  ?  77  GLY B HA3  1 
ATOM   5110  N N    . LYS B 2 83  ? 103.767 102.039 132.966 1.00 25.01  ?  78  LYS B N    1 
ATOM   5111  C CA   . LYS B 2 83  ? 102.808 100.988 132.660 1.00 25.01  ?  78  LYS B CA   1 
ATOM   5112  C C    . LYS B 2 83  ? 103.463 99.619  132.775 1.00 25.01  ?  78  LYS B C    1 
ATOM   5113  O O    . LYS B 2 83  ? 104.564 99.399  132.261 1.00 25.01  ?  78  LYS B O    1 
ATOM   5114  C CB   . LYS B 2 83  ? 102.232 101.169 131.252 1.00 25.01  ?  78  LYS B CB   1 
ATOM   5115  C CG   . LYS B 2 83  ? 100.833 100.590 131.059 1.00 25.01  ?  78  LYS B CG   1 
ATOM   5116  C CD   . LYS B 2 83  ? 99.772  101.322 131.875 1.00 25.01  ?  78  LYS B CD   1 
ATOM   5117  C CE   . LYS B 2 83  ? 99.577  102.754 131.405 1.00 25.01  ?  78  LYS B CE   1 
ATOM   5118  N NZ   . LYS B 2 83  ? 98.472  103.425 132.140 1.00 25.01  1  78  LYS B NZ   1 
ATOM   5119  H H    . LYS B 2 83  ? 104.455 102.033 132.451 1.00 25.01  ?  78  LYS B H    1 
ATOM   5120  H HA   . LYS B 2 83  ? 102.082 101.024 133.300 1.00 25.01  ?  78  LYS B HA   1 
ATOM   5121  H HB2  . LYS B 2 83  ? 102.197 102.116 131.048 1.00 25.01  ?  78  LYS B HB2  1 
ATOM   5122  H HB3  . LYS B 2 83  ? 102.820 100.724 130.622 1.00 25.01  ?  78  LYS B HB3  1 
ATOM   5123  H HG2  . LYS B 2 83  ? 100.590 100.656 130.122 1.00 25.01  ?  78  LYS B HG2  1 
ATOM   5124  H HG3  . LYS B 2 83  ? 100.835 99.660  131.336 1.00 25.01  ?  78  LYS B HG3  1 
ATOM   5125  H HD2  . LYS B 2 83  ? 98.925  100.859 131.777 1.00 25.01  ?  78  LYS B HD2  1 
ATOM   5126  H HD3  . LYS B 2 83  ? 100.031 101.342 132.808 1.00 25.01  ?  78  LYS B HD3  1 
ATOM   5127  H HE2  . LYS B 2 83  ? 100.390 103.258 131.561 1.00 25.01  ?  78  LYS B HE2  1 
ATOM   5128  H HE3  . LYS B 2 83  ? 99.358  102.754 130.460 1.00 25.01  ?  78  LYS B HE3  1 
ATOM   5129  H HZ1  . LYS B 2 83  ? 98.463  104.294 131.948 1.00 25.01  ?  78  LYS B HZ1  1 
ATOM   5130  H HZ2  . LYS B 2 83  ? 98.586  103.324 133.017 1.00 25.01  ?  78  LYS B HZ2  1 
ATOM   5131  H HZ3  . LYS B 2 83  ? 97.691  103.068 131.907 1.00 25.01  ?  78  LYS B HZ3  1 
ATOM   5132  N N    . LEU B 2 84  ? 102.776 98.704  133.456 1.00 23.83  ?  79  LEU B N    1 
ATOM   5133  C CA   . LEU B 2 84  ? 103.181 97.307  133.565 1.00 23.83  ?  79  LEU B CA   1 
ATOM   5134  C C    . LEU B 2 84  ? 102.095 96.469  132.900 1.00 23.83  ?  79  LEU B C    1 
ATOM   5135  O O    . LEU B 2 84  ? 100.943 96.470  133.347 1.00 23.83  ?  79  LEU B O    1 
ATOM   5136  C CB   . LEU B 2 84  ? 103.379 96.909  135.026 1.00 23.83  ?  79  LEU B CB   1 
ATOM   5137  C CG   . LEU B 2 84  ? 104.027 95.548  135.289 1.00 23.83  ?  79  LEU B CG   1 
ATOM   5138  C CD1  . LEU B 2 84  ? 105.496 95.565  134.904 1.00 23.83  ?  79  LEU B CD1  1 
ATOM   5139  C CD2  . LEU B 2 84  ? 103.861 95.157  136.748 1.00 23.83  ?  79  LEU B CD2  1 
ATOM   5140  H H    . LEU B 2 84  ? 102.047 98.878  133.877 1.00 23.83  ?  79  LEU B H    1 
ATOM   5141  H HA   . LEU B 2 84  ? 104.014 97.168  133.090 1.00 23.83  ?  79  LEU B HA   1 
ATOM   5142  H HB2  . LEU B 2 84  ? 103.939 97.579  135.448 1.00 23.83  ?  79  LEU B HB2  1 
ATOM   5143  H HB3  . LEU B 2 84  ? 102.512 96.900  135.458 1.00 23.83  ?  79  LEU B HB3  1 
ATOM   5144  H HG   . LEU B 2 84  ? 103.583 94.878  134.747 1.00 23.83  ?  79  LEU B HG   1 
ATOM   5145  H HD11 . LEU B 2 84  ? 105.569 95.710  133.949 1.00 23.83  ?  79  LEU B HD11 1 
ATOM   5146  H HD12 . LEU B 2 84  ? 105.894 94.712  135.140 1.00 23.83  ?  79  LEU B HD12 1 
ATOM   5147  H HD13 . LEU B 2 84  ? 105.940 96.281  135.384 1.00 23.83  ?  79  LEU B HD13 1 
ATOM   5148  H HD21 . LEU B 2 84  ? 102.925 94.968  136.920 1.00 23.83  ?  79  LEU B HD21 1 
ATOM   5149  H HD22 . LEU B 2 84  ? 104.159 95.892  137.308 1.00 23.83  ?  79  LEU B HD22 1 
ATOM   5150  H HD23 . LEU B 2 84  ? 104.396 94.368  136.925 1.00 23.83  ?  79  LEU B HD23 1 
ATOM   5151  N N    . ILE B 2 85  ? 102.461 95.758  131.837 1.00 23.93  ?  80  ILE B N    1 
ATOM   5152  C CA   . ILE B 2 85  ? 101.508 95.061  130.981 1.00 23.93  ?  80  ILE B CA   1 
ATOM   5153  C C    . ILE B 2 85  ? 101.793 93.567  131.042 1.00 23.93  ?  80  ILE B C    1 
ATOM   5154  O O    . ILE B 2 85  ? 102.955 93.148  130.995 1.00 23.93  ?  80  ILE B O    1 
ATOM   5155  C CB   . ILE B 2 85  ? 101.577 95.569  129.529 1.00 23.93  ?  80  ILE B CB   1 
ATOM   5156  C CG1  . ILE B 2 85  ? 101.140 97.035  129.464 1.00 23.93  ?  80  ILE B CG1  1 
ATOM   5157  C CG2  . ILE B 2 85  ? 100.710 94.703  128.620 1.00 23.93  ?  80  ILE B CG2  1 
ATOM   5158  C CD1  . ILE B 2 85  ? 101.304 97.670  128.097 1.00 23.93  ?  80  ILE B CD1  1 
ATOM   5159  H H    . ILE B 2 85  ? 103.278 95.662  131.586 1.00 23.93  ?  80  ILE B H    1 
ATOM   5160  H HA   . ILE B 2 85  ? 100.609 95.211  131.312 1.00 23.93  ?  80  ILE B HA   1 
ATOM   5161  H HB   . ILE B 2 85  ? 102.496 95.508  129.226 1.00 23.93  ?  80  ILE B HB   1 
ATOM   5162  H HG12 . ILE B 2 85  ? 100.202 97.091  129.704 1.00 23.93  ?  80  ILE B HG12 1 
ATOM   5163  H HG13 . ILE B 2 85  ? 101.671 97.547  130.093 1.00 23.93  ?  80  ILE B HG13 1 
ATOM   5164  H HG21 . ILE B 2 85  ? 101.126 93.833  128.515 1.00 23.93  ?  80  ILE B HG21 1 
ATOM   5165  H HG22 . ILE B 2 85  ? 99.832  94.604  129.022 1.00 23.93  ?  80  ILE B HG22 1 
ATOM   5166  H HG23 . ILE B 2 85  ? 100.630 95.128  127.753 1.00 23.93  ?  80  ILE B HG23 1 
ATOM   5167  H HD11 . ILE B 2 85  ? 101.262 98.635  128.191 1.00 23.93  ?  80  ILE B HD11 1 
ATOM   5168  H HD12 . ILE B 2 85  ? 102.164 97.411  127.731 1.00 23.93  ?  80  ILE B HD12 1 
ATOM   5169  H HD13 . ILE B 2 85  ? 100.591 97.362  127.516 1.00 23.93  ?  80  ILE B HD13 1 
ATOM   5170  N N    . ILE B 2 86  ? 100.730 92.772  131.143 1.00 24.24  ?  81  ILE B N    1 
ATOM   5171  C CA   . ILE B 2 86  ? 100.812 91.317  131.077 1.00 24.24  ?  81  ILE B CA   1 
ATOM   5172  C C    . ILE B 2 86  ? 100.313 90.884  129.707 1.00 24.24  ?  81  ILE B C    1 
ATOM   5173  O O    . ILE B 2 86  ? 99.223  91.286  129.279 1.00 24.24  ?  81  ILE B O    1 
ATOM   5174  C CB   . ILE B 2 86  ? 99.995  90.658  132.202 1.00 24.24  ?  81  ILE B CB   1 
ATOM   5175  C CG1  . ILE B 2 86  ? 100.472 91.164  133.567 1.00 24.24  ?  81  ILE B CG1  1 
ATOM   5176  C CG2  . ILE B 2 86  ? 100.109 89.139  132.125 1.00 24.24  ?  81  ILE B CG2  1 
ATOM   5177  C CD1  . ILE B 2 86  ? 99.677  90.627  134.739 1.00 24.24  ?  81  ILE B CD1  1 
ATOM   5178  H H    . ILE B 2 86  ? 99.928  93.062  131.255 1.00 24.24  ?  81  ILE B H    1 
ATOM   5179  H HA   . ILE B 2 86  ? 101.737 91.040  131.169 1.00 24.24  ?  81  ILE B HA   1 
ATOM   5180  H HB   . ILE B 2 86  ? 99.063  90.904  132.090 1.00 24.24  ?  81  ILE B HB   1 
ATOM   5181  H HG12 . ILE B 2 86  ? 101.397 90.899  133.691 1.00 24.24  ?  81  ILE B HG12 1 
ATOM   5182  H HG13 . ILE B 2 86  ? 100.403 92.131  133.585 1.00 24.24  ?  81  ILE B HG13 1 
ATOM   5183  H HG21 . ILE B 2 86  ? 99.593  88.743  132.843 1.00 24.24  ?  81  ILE B HG21 1 
ATOM   5184  H HG22 . ILE B 2 86  ? 99.764  88.834  131.271 1.00 24.24  ?  81  ILE B HG22 1 
ATOM   5185  H HG23 . ILE B 2 86  ? 101.043 88.889  132.212 1.00 24.24  ?  81  ILE B HG23 1 
ATOM   5186  H HD11 . ILE B 2 86  ? 99.908  91.132  135.534 1.00 24.24  ?  81  ILE B HD11 1 
ATOM   5187  H HD12 . ILE B 2 86  ? 98.731  90.723  134.548 1.00 24.24  ?  81  ILE B HD12 1 
ATOM   5188  H HD13 . ILE B 2 86  ? 99.895  89.690  134.867 1.00 24.24  ?  81  ILE B HD13 1 
ATOM   5189  N N    . TRP B 2 87  ? 101.103 90.066  129.019 1.00 23.82  ?  82  TRP B N    1 
ATOM   5190  C CA   . TRP B 2 87  ? 100.846 89.694  127.636 1.00 23.82  ?  82  TRP B CA   1 
ATOM   5191  C C    . TRP B 2 87  ? 100.476 88.221  127.535 1.00 23.82  ?  82  TRP B C    1 
ATOM   5192  O O    . TRP B 2 87  ? 101.024 87.382  128.257 1.00 23.82  ?  82  TRP B O    1 
ATOM   5193  C CB   . TRP B 2 87  ? 102.073 89.968  126.762 1.00 23.82  ?  82 