data_8BE5
# 
_entry.id   8BE5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.380 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8BE5         pdb_00008be5 10.2210/pdb8be5/pdb 
WWPDB D_1292126210 ?            ?                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8BE5 
_pdbx_database_status.recvd_initial_deposition_date   2022-10-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fischer, B.'   1 ? 
'Wohlkonig, A.' 2 ? 
'Steyaert, J.'  3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fischer, B.'   1 ? 
primary 'Wohlkonig, A.' 2 ? 
primary 'Steyaert, J.'  3 ? 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8BE5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     124.080 
_cell.length_a_esd                 ? 
_cell.length_b                     124.080 
_cell.length_b_esd                 ? 
_cell.length_c                     408.815 
_cell.length_c_esd                 ? 
_cell.volume                       6294052.946 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8BE5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                97 
_symmetry.space_group_name_Hall            'I 4 2' 
_symmetry.space_group_name_H-M             'I 4 2 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Son of sevenless homolog 1' 59348.816 1  ?       ?    ? ? 
2 polymer man Nanobody75                   14658.214 1  ?       ?    ? ? 
3 polymer man 'Isoform 2B of GTPase KRas'  21675.314 1  3.6.5.2 G12V ? ? 
4 polymer man Nanobody22                   13892.469 1  ?       ?    ? ? 
5 water   nat water                        18.015    19 ?       ?    ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 SOS-1                             
3 'K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGSSHHHHHHSSGLVPRGSHMEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPN
FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFY
DFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPI
EIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVF
QELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEE
GNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPK
PLPRFPKKYSYPLKSPGVRPSNPRPGT
;
;MGSSHHHHHHSSGLVPRGSHMEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPN
FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFY
DFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPI
EIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVF
QELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEE
GNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPK
PLPRFPKKYSYPLKSPGVRPSNPRPGT
;
AAZA ? 
2 'polypeptide(L)' no no 
;QVQLVESGGGLVQAGGSLRLSCAASGNILPINVMGWYRQTPGSQRELVATIVTSGGSTAGNTNYVDSVKGRFTISGDNAK
NTVYLQMSSLKPEDTAVYYCNLKTRRAPWATPNNYWGQGTQVTVSSHHHHHHEPEA
;
;QVQLVESGGGLVQAGGSLRLSCAASGNILPINVMGWYRQTPGSQRELVATIVTSGGSTAGNTNYVDSVKGRFTISGDNAK
NTVYLQMSSLKPEDTAVYYCNLKTRRAPWATPNNYWGQGTQVTVSSHHHHHHEPEA
;
C    ? 
3 'polypeptide(L)' no no 
;MGSSHHHHHHSSGENLYFQGSMTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTA
GQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGI
PFIETSAKTRQGVDDAFYTLVREIRKHKEK
;
;MGSSHHHHHHSSGENLYFQGSMTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTA
GQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGI
PFIETSAKTRQGVDDAFYTLVREIRKHKEK
;
R    ? 
4 'polypeptide(L)' no no 
;QVQLVESGGGLVQAEGSLRLSCLVSGDIVRSNLMGWYRQAPGKQREFVARINPTGSANYADSVRGRFTISKDNSKKTLYL
QMGSLQPEDTAVYYCRLIQNRDYWGQGTQVTVSSHHHHHHEPEA
;
;QVQLVESGGGLVQAEGSLRLSCLVSGDIVRSNLMGWYRQAPGKQREFVARINPTGSANYADSVRGRFTISKDNSKKTLYL
QMGSLQPEDTAVYYCRLIQNRDYWGQGTQVTVSSHHHHHHEPEA
;
N    ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  GLU n 
1 23  GLU n 
1 24  GLN n 
1 25  MET n 
1 26  ARG n 
1 27  LEU n 
1 28  PRO n 
1 29  SER n 
1 30  ALA n 
1 31  ASP n 
1 32  VAL n 
1 33  TYR n 
1 34  ARG n 
1 35  PHE n 
1 36  ALA n 
1 37  GLU n 
1 38  PRO n 
1 39  ASP n 
1 40  SER n 
1 41  GLU n 
1 42  GLU n 
1 43  ASN n 
1 44  ILE n 
1 45  ILE n 
1 46  PHE n 
1 47  GLU n 
1 48  GLU n 
1 49  ASN n 
1 50  MET n 
1 51  GLN n 
1 52  PRO n 
1 53  LYS n 
1 54  ALA n 
1 55  GLY n 
1 56  ILE n 
1 57  PRO n 
1 58  ILE n 
1 59  ILE n 
1 60  LYS n 
1 61  ALA n 
1 62  GLY n 
1 63  THR n 
1 64  VAL n 
1 65  ILE n 
1 66  LYS n 
1 67  LEU n 
1 68  ILE n 
1 69  GLU n 
1 70  ARG n 
1 71  LEU n 
1 72  THR n 
1 73  TYR n 
1 74  HIS n 
1 75  MET n 
1 76  TYR n 
1 77  ALA n 
1 78  ASP n 
1 79  PRO n 
1 80  ASN n 
1 81  PHE n 
1 82  VAL n 
1 83  ARG n 
1 84  THR n 
1 85  PHE n 
1 86  LEU n 
1 87  THR n 
1 88  THR n 
1 89  TYR n 
1 90  ARG n 
1 91  SER n 
1 92  PHE n 
1 93  CYS n 
1 94  LYS n 
1 95  PRO n 
1 96  GLN n 
1 97  GLU n 
1 98  LEU n 
1 99  LEU n 
1 100 SER n 
1 101 LEU n 
1 102 ILE n 
1 103 ILE n 
1 104 GLU n 
1 105 ARG n 
1 106 PHE n 
1 107 GLU n 
1 108 ILE n 
1 109 PRO n 
1 110 GLU n 
1 111 PRO n 
1 112 GLU n 
1 113 PRO n 
1 114 THR n 
1 115 GLU n 
1 116 ALA n 
1 117 ASP n 
1 118 ARG n 
1 119 ILE n 
1 120 ALA n 
1 121 ILE n 
1 122 GLU n 
1 123 ASN n 
1 124 GLY n 
1 125 ASP n 
1 126 GLN n 
1 127 PRO n 
1 128 LEU n 
1 129 SER n 
1 130 ALA n 
1 131 GLU n 
1 132 LEU n 
1 133 LYS n 
1 134 ARG n 
1 135 PHE n 
1 136 ARG n 
1 137 LYS n 
1 138 GLU n 
1 139 TYR n 
1 140 ILE n 
1 141 GLN n 
1 142 PRO n 
1 143 VAL n 
1 144 GLN n 
1 145 LEU n 
1 146 ARG n 
1 147 VAL n 
1 148 LEU n 
1 149 ASN n 
1 150 VAL n 
1 151 CYS n 
1 152 ARG n 
1 153 HIS n 
1 154 TRP n 
1 155 VAL n 
1 156 GLU n 
1 157 HIS n 
1 158 HIS n 
1 159 PHE n 
1 160 TYR n 
1 161 ASP n 
1 162 PHE n 
1 163 GLU n 
1 164 ARG n 
1 165 ASP n 
1 166 ALA n 
1 167 TYR n 
1 168 LEU n 
1 169 LEU n 
1 170 GLN n 
1 171 ARG n 
1 172 MET n 
1 173 GLU n 
1 174 GLU n 
1 175 PHE n 
1 176 ILE n 
1 177 GLY n 
1 178 THR n 
1 179 VAL n 
1 180 ARG n 
1 181 GLY n 
1 182 LYS n 
1 183 ALA n 
1 184 MET n 
1 185 LYS n 
1 186 LYS n 
1 187 TRP n 
1 188 VAL n 
1 189 GLU n 
1 190 SER n 
1 191 ILE n 
1 192 THR n 
1 193 LYS n 
1 194 ILE n 
1 195 ILE n 
1 196 GLN n 
1 197 ARG n 
1 198 LYS n 
1 199 LYS n 
1 200 ILE n 
1 201 ALA n 
1 202 ARG n 
1 203 ASP n 
1 204 ASN n 
1 205 GLY n 
1 206 PRO n 
1 207 GLY n 
1 208 HIS n 
1 209 ASN n 
1 210 ILE n 
1 211 THR n 
1 212 PHE n 
1 213 GLN n 
1 214 SER n 
1 215 SER n 
1 216 PRO n 
1 217 PRO n 
1 218 THR n 
1 219 VAL n 
1 220 GLU n 
1 221 TRP n 
1 222 HIS n 
1 223 ILE n 
1 224 SER n 
1 225 ARG n 
1 226 PRO n 
1 227 GLY n 
1 228 HIS n 
1 229 ILE n 
1 230 GLU n 
1 231 THR n 
1 232 PHE n 
1 233 ASP n 
1 234 LEU n 
1 235 LEU n 
1 236 THR n 
1 237 LEU n 
1 238 HIS n 
1 239 PRO n 
1 240 ILE n 
1 241 GLU n 
1 242 ILE n 
1 243 ALA n 
1 244 ARG n 
1 245 GLN n 
1 246 LEU n 
1 247 THR n 
1 248 LEU n 
1 249 LEU n 
1 250 GLU n 
1 251 SER n 
1 252 ASP n 
1 253 LEU n 
1 254 TYR n 
1 255 ARG n 
1 256 ALA n 
1 257 VAL n 
1 258 GLN n 
1 259 PRO n 
1 260 SER n 
1 261 GLU n 
1 262 LEU n 
1 263 VAL n 
1 264 GLY n 
1 265 SER n 
1 266 VAL n 
1 267 TRP n 
1 268 THR n 
1 269 LYS n 
1 270 GLU n 
1 271 ASP n 
1 272 LYS n 
1 273 GLU n 
1 274 ILE n 
1 275 ASN n 
1 276 SER n 
1 277 PRO n 
1 278 ASN n 
1 279 LEU n 
1 280 LEU n 
1 281 LYS n 
1 282 MET n 
1 283 ILE n 
1 284 ARG n 
1 285 HIS n 
1 286 THR n 
1 287 THR n 
1 288 ASN n 
1 289 LEU n 
1 290 THR n 
1 291 LEU n 
1 292 TRP n 
1 293 PHE n 
1 294 GLU n 
1 295 LYS n 
1 296 CYS n 
1 297 ILE n 
1 298 VAL n 
1 299 GLU n 
1 300 THR n 
1 301 GLU n 
1 302 ASN n 
1 303 LEU n 
1 304 GLU n 
1 305 GLU n 
1 306 ARG n 
1 307 VAL n 
1 308 ALA n 
1 309 VAL n 
1 310 VAL n 
1 311 SER n 
1 312 ARG n 
1 313 ILE n 
1 314 ILE n 
1 315 GLU n 
1 316 ILE n 
1 317 LEU n 
1 318 GLN n 
1 319 VAL n 
1 320 PHE n 
1 321 GLN n 
1 322 GLU n 
1 323 LEU n 
1 324 ASN n 
1 325 ASN n 
1 326 PHE n 
1 327 ASN n 
1 328 GLY n 
1 329 VAL n 
1 330 LEU n 
1 331 GLU n 
1 332 VAL n 
1 333 VAL n 
1 334 SER n 
1 335 ALA n 
1 336 MET n 
1 337 ASN n 
1 338 SER n 
1 339 SER n 
1 340 PRO n 
1 341 VAL n 
1 342 TYR n 
1 343 ARG n 
1 344 LEU n 
1 345 ASP n 
1 346 HIS n 
1 347 THR n 
1 348 PHE n 
1 349 GLU n 
1 350 GLN n 
1 351 ILE n 
1 352 PRO n 
1 353 SER n 
1 354 ARG n 
1 355 GLN n 
1 356 LYS n 
1 357 LYS n 
1 358 ILE n 
1 359 LEU n 
1 360 GLU n 
1 361 GLU n 
1 362 ALA n 
1 363 HIS n 
1 364 GLU n 
1 365 LEU n 
1 366 SER n 
1 367 GLU n 
1 368 ASP n 
1 369 HIS n 
1 370 TYR n 
1 371 LYS n 
1 372 LYS n 
1 373 TYR n 
1 374 LEU n 
1 375 ALA n 
1 376 LYS n 
1 377 LEU n 
1 378 ARG n 
1 379 SER n 
1 380 ILE n 
1 381 ASN n 
1 382 PRO n 
1 383 PRO n 
1 384 CYS n 
1 385 VAL n 
1 386 PRO n 
1 387 PHE n 
1 388 PHE n 
1 389 GLY n 
1 390 ILE n 
1 391 TYR n 
1 392 LEU n 
1 393 THR n 
1 394 ASN n 
1 395 ILE n 
1 396 LEU n 
1 397 LYS n 
1 398 THR n 
1 399 GLU n 
1 400 GLU n 
1 401 GLY n 
1 402 ASN n 
1 403 PRO n 
1 404 GLU n 
1 405 VAL n 
1 406 LEU n 
1 407 LYS n 
1 408 ARG n 
1 409 HIS n 
1 410 GLY n 
1 411 LYS n 
1 412 GLU n 
1 413 LEU n 
1 414 ILE n 
1 415 ASN n 
1 416 PHE n 
1 417 SER n 
1 418 LYS n 
1 419 ARG n 
1 420 ARG n 
1 421 LYS n 
1 422 VAL n 
1 423 ALA n 
1 424 GLU n 
1 425 ILE n 
1 426 THR n 
1 427 GLY n 
1 428 GLU n 
1 429 ILE n 
1 430 GLN n 
1 431 GLN n 
1 432 TYR n 
1 433 GLN n 
1 434 ASN n 
1 435 GLN n 
1 436 PRO n 
1 437 TYR n 
1 438 CYS n 
1 439 LEU n 
1 440 ARG n 
1 441 VAL n 
1 442 GLU n 
1 443 SER n 
1 444 ASP n 
1 445 ILE n 
1 446 LYS n 
1 447 ARG n 
1 448 PHE n 
1 449 PHE n 
1 450 GLU n 
1 451 ASN n 
1 452 LEU n 
1 453 ASN n 
1 454 PRO n 
1 455 MET n 
1 456 GLY n 
1 457 ASN n 
1 458 SER n 
1 459 MET n 
1 460 GLU n 
1 461 LYS n 
1 462 GLU n 
1 463 PHE n 
1 464 THR n 
1 465 ASP n 
1 466 TYR n 
1 467 LEU n 
1 468 PHE n 
1 469 ASN n 
1 470 LYS n 
1 471 SER n 
1 472 LEU n 
1 473 GLU n 
1 474 ILE n 
1 475 GLU n 
1 476 PRO n 
1 477 ARG n 
1 478 ASN n 
1 479 PRO n 
1 480 LYS n 
1 481 PRO n 
1 482 LEU n 
1 483 PRO n 
1 484 ARG n 
1 485 PHE n 
1 486 PRO n 
1 487 LYS n 
1 488 LYS n 
1 489 TYR n 
1 490 SER n 
1 491 TYR n 
1 492 PRO n 
1 493 LEU n 
1 494 LYS n 
1 495 SER n 
1 496 PRO n 
1 497 GLY n 
1 498 VAL n 
1 499 ARG n 
1 500 PRO n 
1 501 SER n 
1 502 ASN n 
1 503 PRO n 
1 504 ARG n 
1 505 PRO n 
1 506 GLY n 
1 507 THR n 
2 1   GLN n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLU n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  LEU n 
2 12  VAL n 
2 13  GLN n 
2 14  ALA n 
2 15  GLY n 
2 16  GLY n 
2 17  SER n 
2 18  LEU n 
2 19  ARG n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  ALA n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  ASN n 
2 28  ILE n 
2 29  LEU n 
2 30  PRO n 
2 31  ILE n 
2 32  ASN n 
2 33  VAL n 
2 34  MET n 
2 35  GLY n 
2 36  TRP n 
2 37  TYR n 
2 38  ARG n 
2 39  GLN n 
2 40  THR n 
2 41  PRO n 
2 42  GLY n 
2 43  SER n 
2 44  GLN n 
2 45  ARG n 
2 46  GLU n 
2 47  LEU n 
2 48  VAL n 
2 49  ALA n 
2 50  THR n 
2 51  ILE n 
2 52  VAL n 
2 53  THR n 
2 54  SER n 
2 55  GLY n 
2 56  GLY n 
2 57  SER n 
2 58  THR n 
2 59  ALA n 
2 60  GLY n 
2 61  ASN n 
2 62  THR n 
2 63  ASN n 
2 64  TYR n 
2 65  VAL n 
2 66  ASP n 
2 67  SER n 
2 68  VAL n 
2 69  LYS n 
2 70  GLY n 
2 71  ARG n 
2 72  PHE n 
2 73  THR n 
2 74  ILE n 
2 75  SER n 
2 76  GLY n 
2 77  ASP n 
2 78  ASN n 
2 79  ALA n 
2 80  LYS n 
2 81  ASN n 
2 82  THR n 
2 83  VAL n 
2 84  TYR n 
2 85  LEU n 
2 86  GLN n 
2 87  MET n 
2 88  SER n 
2 89  SER n 
2 90  LEU n 
2 91  LYS n 
2 92  PRO n 
2 93  GLU n 
2 94  ASP n 
2 95  THR n 
2 96  ALA n 
2 97  VAL n 
2 98  TYR n 
2 99  TYR n 
2 100 CYS n 
2 101 ASN n 
2 102 LEU n 
2 103 LYS n 
2 104 THR n 
2 105 ARG n 
2 106 ARG n 
2 107 ALA n 
2 108 PRO n 
2 109 TRP n 
2 110 ALA n 
2 111 THR n 
2 112 PRO n 
2 113 ASN n 
2 114 ASN n 
2 115 TYR n 
2 116 TRP n 
2 117 GLY n 
2 118 GLN n 
2 119 GLY n 
2 120 THR n 
2 121 GLN n 
2 122 VAL n 
2 123 THR n 
2 124 VAL n 
2 125 SER n 
2 126 SER n 
2 127 HIS n 
2 128 HIS n 
2 129 HIS n 
2 130 HIS n 
2 131 HIS n 
2 132 HIS n 
2 133 GLU n 
2 134 PRO n 
2 135 GLU n 
2 136 ALA n 
3 1   MET n 
3 2   GLY n 
3 3   SER n 
3 4   SER n 
3 5   HIS n 
3 6   HIS n 
3 7   HIS n 
3 8   HIS n 
3 9   HIS n 
3 10  HIS n 
3 11  SER n 
3 12  SER n 
3 13  GLY n 
3 14  GLU n 
3 15  ASN n 
3 16  LEU n 
3 17  TYR n 
3 18  PHE n 
3 19  GLN n 
3 20  GLY n 
3 21  SER n 
3 22  MET n 
3 23  THR n 
3 24  GLU n 
3 25  TYR n 
3 26  LYS n 
3 27  LEU n 
3 28  VAL n 
3 29  VAL n 
3 30  VAL n 
3 31  GLY n 
3 32  ALA n 
3 33  VAL n 
3 34  GLY n 
3 35  VAL n 
3 36  GLY n 
3 37  LYS n 
3 38  SER n 
3 39  ALA n 
3 40  LEU n 
3 41  THR n 
3 42  ILE n 
3 43  GLN n 
3 44  LEU n 
3 45  ILE n 
3 46  GLN n 
3 47  ASN n 
3 48  HIS n 
3 49  PHE n 
3 50  VAL n 
3 51  ASP n 
3 52  GLU n 
3 53  TYR n 
3 54  ASP n 
3 55  PRO n 
3 56  THR n 
3 57  ILE n 
3 58  GLU n 
3 59  ASP n 
3 60  SER n 
3 61  TYR n 
3 62  ARG n 
3 63  LYS n 
3 64  GLN n 
3 65  VAL n 
3 66  VAL n 
3 67  ILE n 
3 68  ASP n 
3 69  GLY n 
3 70  GLU n 
3 71  THR n 
3 72  CYS n 
3 73  LEU n 
3 74  LEU n 
3 75  ASP n 
3 76  ILE n 
3 77  LEU n 
3 78  ASP n 
3 79  THR n 
3 80  ALA n 
3 81  GLY n 
3 82  GLN n 
3 83  GLU n 
3 84  GLU n 
3 85  TYR n 
3 86  SER n 
3 87  ALA n 
3 88  MET n 
3 89  ARG n 
3 90  ASP n 
3 91  GLN n 
3 92  TYR n 
3 93  MET n 
3 94  ARG n 
3 95  THR n 
3 96  GLY n 
3 97  GLU n 
3 98  GLY n 
3 99  PHE n 
3 100 LEU n 
3 101 CYS n 
3 102 VAL n 
3 103 PHE n 
3 104 ALA n 
3 105 ILE n 
3 106 ASN n 
3 107 ASN n 
3 108 THR n 
3 109 LYS n 
3 110 SER n 
3 111 PHE n 
3 112 GLU n 
3 113 ASP n 
3 114 ILE n 
3 115 HIS n 
3 116 HIS n 
3 117 TYR n 
3 118 ARG n 
3 119 GLU n 
3 120 GLN n 
3 121 ILE n 
3 122 LYS n 
3 123 ARG n 
3 124 VAL n 
3 125 LYS n 
3 126 ASP n 
3 127 SER n 
3 128 GLU n 
3 129 ASP n 
3 130 VAL n 
3 131 PRO n 
3 132 MET n 
3 133 VAL n 
3 134 LEU n 
3 135 VAL n 
3 136 GLY n 
3 137 ASN n 
3 138 LYS n 
3 139 CYS n 
3 140 ASP n 
3 141 LEU n 
3 142 PRO n 
3 143 SER n 
3 144 ARG n 
3 145 THR n 
3 146 VAL n 
3 147 ASP n 
3 148 THR n 
3 149 LYS n 
3 150 GLN n 
3 151 ALA n 
3 152 GLN n 
3 153 ASP n 
3 154 LEU n 
3 155 ALA n 
3 156 ARG n 
3 157 SER n 
3 158 TYR n 
3 159 GLY n 
3 160 ILE n 
3 161 PRO n 
3 162 PHE n 
3 163 ILE n 
3 164 GLU n 
3 165 THR n 
3 166 SER n 
3 167 ALA n 
3 168 LYS n 
3 169 THR n 
3 170 ARG n 
3 171 GLN n 
3 172 GLY n 
3 173 VAL n 
3 174 ASP n 
3 175 ASP n 
3 176 ALA n 
3 177 PHE n 
3 178 TYR n 
3 179 THR n 
3 180 LEU n 
3 181 VAL n 
3 182 ARG n 
3 183 GLU n 
3 184 ILE n 
3 185 ARG n 
3 186 LYS n 
3 187 HIS n 
3 188 LYS n 
3 189 GLU n 
3 190 LYS n 
4 1   GLN n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  ALA n 
4 15  GLU n 
4 16  GLY n 
4 17  SER n 
4 18  LEU n 
4 19  ARG n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  LEU n 
4 24  VAL n 
4 25  SER n 
4 26  GLY n 
4 27  ASP n 
4 28  ILE n 
4 29  VAL n 
4 30  ARG n 
4 31  SER n 
4 32  ASN n 
4 33  LEU n 
4 34  MET n 
4 35  GLY n 
4 36  TRP n 
4 37  TYR n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLY n 
4 43  LYS n 
4 44  GLN n 
4 45  ARG n 
4 46  GLU n 
4 47  PHE n 
4 48  VAL n 
4 49  ALA n 
4 50  ARG n 
4 51  ILE n 
4 52  ASN n 
4 53  PRO n 
4 54  THR n 
4 55  GLY n 
4 56  SER n 
4 57  ALA n 
4 58  ASN n 
4 59  TYR n 
4 60  ALA n 
4 61  ASP n 
4 62  SER n 
4 63  VAL n 
4 64  ARG n 
4 65  GLY n 
4 66  ARG n 
4 67  PHE n 
4 68  THR n 
4 69  ILE n 
4 70  SER n 
4 71  LYS n 
4 72  ASP n 
4 73  ASN n 
4 74  SER n 
4 75  LYS n 
4 76  LYS n 
4 77  THR n 
4 78  LEU n 
4 79  TYR n 
4 80  LEU n 
4 81  GLN n 
4 82  MET n 
4 83  GLY n 
4 84  SER n 
4 85  LEU n 
4 86  GLN n 
4 87  PRO n 
4 88  GLU n 
4 89  ASP n 
4 90  THR n 
4 91  ALA n 
4 92  VAL n 
4 93  TYR n 
4 94  TYR n 
4 95  CYS n 
4 96  ARG n 
4 97  LEU n 
4 98  ILE n 
4 99  GLN n 
4 100 ASN n 
4 101 ARG n 
4 102 ASP n 
4 103 TYR n 
4 104 TRP n 
4 105 GLY n 
4 106 GLN n 
4 107 GLY n 
4 108 THR n 
4 109 GLN n 
4 110 VAL n 
4 111 THR n 
4 112 VAL n 
4 113 SER n 
4 114 SER n 
4 115 HIS n 
4 116 HIS n 
4 117 HIS n 
4 118 HIS n 
4 119 HIS n 
4 120 HIS n 
4 121 GLU n 
4 122 PRO n 
4 123 GLU n 
4 124 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 507 human ? SOS1                 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 136 ?     ? ?                    ? ? ? ? ? ? 'Lama glama'   9844 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 190 human ? 'KRAS, KRAS2, RASK2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 124 ?     ? ?                    ? ? ? ? ? ? 'Lama glama'   9844 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP SOS1_HUMAN Q07889   ? 1 
;EEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSL
IIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG
KAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSE
LVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPV
YRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRK
VAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPS
NPRPGT
;
564 
2 PDB 8BE5       8BE5     ? 2 ? 1   
3 UNP RASK_HUMAN P01116-2 ? 3 
;MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLC
VFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLV
REIRKHKEK
;
1   
4 PDB 8BE5       8BE5     ? 4 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8BE5 AAZA 22 ? 507 ? Q07889   564 ? 1049 ? 564 1049 
2 2 8BE5 C    1  ? 136 ? 8BE5     1   ? 136  ? 1   136  
3 3 8BE5 R    22 ? 190 ? P01116-2 1   ? 169  ? 1   169  
4 4 8BE5 N    1  ? 124 ? 8BE5     1   ? 124  ? 1   124  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8BE5 MET AAZA 1  ? UNP Q07889   ?   ?  'initiating methionine' 543 1  
1 8BE5 GLY AAZA 2  ? UNP Q07889   ?   ?  'expression tag'        544 2  
1 8BE5 SER AAZA 3  ? UNP Q07889   ?   ?  'expression tag'        545 3  
1 8BE5 SER AAZA 4  ? UNP Q07889   ?   ?  'expression tag'        546 4  
1 8BE5 HIS AAZA 5  ? UNP Q07889   ?   ?  'expression tag'        547 5  
1 8BE5 HIS AAZA 6  ? UNP Q07889   ?   ?  'expression tag'        548 6  
1 8BE5 HIS AAZA 7  ? UNP Q07889   ?   ?  'expression tag'        549 7  
1 8BE5 HIS AAZA 8  ? UNP Q07889   ?   ?  'expression tag'        550 8  
1 8BE5 HIS AAZA 9  ? UNP Q07889   ?   ?  'expression tag'        551 9  
1 8BE5 HIS AAZA 10 ? UNP Q07889   ?   ?  'expression tag'        552 10 
1 8BE5 SER AAZA 11 ? UNP Q07889   ?   ?  'expression tag'        553 11 
1 8BE5 SER AAZA 12 ? UNP Q07889   ?   ?  'expression tag'        554 12 
1 8BE5 GLY AAZA 13 ? UNP Q07889   ?   ?  'expression tag'        555 13 
1 8BE5 LEU AAZA 14 ? UNP Q07889   ?   ?  'expression tag'        556 14 
1 8BE5 VAL AAZA 15 ? UNP Q07889   ?   ?  'expression tag'        557 15 
1 8BE5 PRO AAZA 16 ? UNP Q07889   ?   ?  'expression tag'        558 16 
1 8BE5 ARG AAZA 17 ? UNP Q07889   ?   ?  'expression tag'        559 17 
1 8BE5 GLY AAZA 18 ? UNP Q07889   ?   ?  'expression tag'        560 18 
1 8BE5 SER AAZA 19 ? UNP Q07889   ?   ?  'expression tag'        561 19 
1 8BE5 HIS AAZA 20 ? UNP Q07889   ?   ?  'expression tag'        562 20 
1 8BE5 MET AAZA 21 ? UNP Q07889   ?   ?  'expression tag'        563 21 
3 8BE5 MET R    1  ? UNP P01116-2 ?   ?  'initiating methionine' -20 22 
3 8BE5 GLY R    2  ? UNP P01116-2 ?   ?  'expression tag'        -19 23 
3 8BE5 SER R    3  ? UNP P01116-2 ?   ?  'expression tag'        -18 24 
3 8BE5 SER R    4  ? UNP P01116-2 ?   ?  'expression tag'        -17 25 
3 8BE5 HIS R    5  ? UNP P01116-2 ?   ?  'expression tag'        -16 26 
3 8BE5 HIS R    6  ? UNP P01116-2 ?   ?  'expression tag'        -15 27 
3 8BE5 HIS R    7  ? UNP P01116-2 ?   ?  'expression tag'        -14 28 
3 8BE5 HIS R    8  ? UNP P01116-2 ?   ?  'expression tag'        -13 29 
3 8BE5 HIS R    9  ? UNP P01116-2 ?   ?  'expression tag'        -12 30 
3 8BE5 HIS R    10 ? UNP P01116-2 ?   ?  'expression tag'        -11 31 
3 8BE5 SER R    11 ? UNP P01116-2 ?   ?  'expression tag'        -10 32 
3 8BE5 SER R    12 ? UNP P01116-2 ?   ?  'expression tag'        -9  33 
3 8BE5 GLY R    13 ? UNP P01116-2 ?   ?  'expression tag'        -8  34 
3 8BE5 GLU R    14 ? UNP P01116-2 ?   ?  'expression tag'        -7  35 
3 8BE5 ASN R    15 ? UNP P01116-2 ?   ?  'expression tag'        -6  36 
3 8BE5 LEU R    16 ? UNP P01116-2 ?   ?  'expression tag'        -5  37 
3 8BE5 TYR R    17 ? UNP P01116-2 ?   ?  'expression tag'        -4  38 
3 8BE5 PHE R    18 ? UNP P01116-2 ?   ?  'expression tag'        -3  39 
3 8BE5 GLN R    19 ? UNP P01116-2 ?   ?  'expression tag'        -2  40 
3 8BE5 GLY R    20 ? UNP P01116-2 ?   ?  'expression tag'        -1  41 
3 8BE5 SER R    21 ? UNP P01116-2 ?   ?  'expression tag'        0   42 
3 8BE5 VAL R    33 ? UNP P01116-2 GLY 12 'engineered mutation'   12  43 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8BE5 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.65 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          66.28 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp            293 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '10% PEG 4000, 0.1 M sodium citrate, pH 5.5 and 0.2 M sodium acetate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2017-12-15 
_diffrn_detector.pdbx_frequency               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.96858 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I24' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.96858 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I24 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          99.89 
_reflns.entry_id                                       8BE5 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.13 
_reflns.d_resolution_low                               30 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     28523 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.3 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                10.8 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          13.65 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
_reflns.pdbx_CC_split_method                           ? 
# 
_reflns_shell.d_res_high                                    3.13 
_reflns_shell.d_res_low                                     3.32 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4364 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.77 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               93.56 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8BE5 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.13 
_refine.ls_d_res_low                             29.91 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     28506 
_refine.ls_number_reflns_R_free                  1426 
_refine.ls_number_reflns_R_work                  27080 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.45 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2286 
_refine.ls_R_factor_R_free                       0.2779 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2260 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      1BKD 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 30.5399 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.5141 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.13 
_refine_hist.d_res_low                        29.91 
_refine_hist.number_atoms_solvent             19 
_refine_hist.number_atoms_total               6443 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6424 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0113  ? 6553 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.3814  ? 8854 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0796  ? 978  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0124  ? 1138 ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 16.8551 ? 2482 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
'X-RAY DIFFRACTION' 3.13 3.24  . . 133 2526 94.96  . . . 0.3959 . 0.3854 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.24 3.37  . . 141 2675 99.79  . . . 0.3470 . 0.3008 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.37 3.53  . . 140 2668 99.96  . . . 0.3625 . 0.2825 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.53 3.71  . . 141 2678 99.96  . . . 0.3244 . 0.2787 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.71 3.95  . . 141 2680 99.96  . . . 0.2872 . 0.2335 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 3.95 4.25  . . 142 2697 100.00 . . . 0.2653 . 0.2115 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 4.25 4.68  . . 143 2716 100.00 . . . 0.2465 . 0.1849 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 4.68 5.35  . . 145 2747 100.00 . . . 0.2435 . 0.1977 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 5.35 6.73  . . 146 2777 99.97  . . . 0.2984 . 0.2470 . . . . . . . . . . . 
'X-RAY DIFFRACTION' 6.73 29.91 . . 154 2916 99.84  . . . 0.2539 . 0.2019 . . . . . . . . . . . 
# 
_struct.entry_id                     8BE5 
_struct.title                        'Crystal structure of SOS1-KRasG12V-Nanobody22-Nanobody75' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8BE5 
_struct_keywords.text            'Complex, Stabilizer, SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TYR A 33  ? GLU A 37  ? TYR AAZA 575  GLU AAZA 579  5 ? 5  
HELX_P HELX_P2  AA2 THR A 63  ? THR A 72  ? THR AAZA 605  THR AAZA 614  1 ? 10 
HELX_P HELX_P3  AA3 ASP A 78  ? TYR A 89  ? ASP AAZA 620  TYR AAZA 631  1 ? 12 
HELX_P HELX_P4  AA4 ARG A 90  ? PHE A 92  ? ARG AAZA 632  PHE AAZA 634  5 ? 3  
HELX_P HELX_P5  AA5 LYS A 94  ? ARG A 105 ? LYS AAZA 636  ARG AAZA 647  1 ? 12 
HELX_P HELX_P6  AA6 LYS A 133 ? GLU A 138 ? LYS AAZA 675  GLU AAZA 680  1 ? 6  
HELX_P HELX_P7  AA7 TYR A 139 ? HIS A 158 ? TYR AAZA 681  HIS AAZA 700  1 ? 20 
HELX_P HELX_P8  AA8 PHE A 159 ? ARG A 164 ? PHE AAZA 701  ARG AAZA 706  1 ? 6  
HELX_P HELX_P9  AA9 ASP A 165 ? VAL A 179 ? ASP AAZA 707  VAL AAZA 721  1 ? 15 
HELX_P HELX_P10 AB1 LYS A 186 ? LYS A 199 ? LYS AAZA 728  LYS AAZA 741  1 ? 14 
HELX_P HELX_P11 AB2 HIS A 228 ? PHE A 232 ? HIS AAZA 770  PHE AAZA 774  5 ? 5  
HELX_P HELX_P12 AB3 HIS A 238 ? ALA A 256 ? HIS AAZA 780  ALA AAZA 798  1 ? 19 
HELX_P HELX_P13 AB4 VAL A 257 ? LEU A 262 ? VAL AAZA 799  LEU AAZA 804  5 ? 6  
HELX_P HELX_P14 AB5 SER A 265 ? LYS A 269 ? SER AAZA 807  LYS AAZA 811  5 ? 5  
HELX_P HELX_P15 AB6 ASP A 271 ? SER A 276 ? ASP AAZA 813  SER AAZA 818  1 ? 6  
HELX_P HELX_P16 AB7 SER A 276 ? GLU A 299 ? SER AAZA 818  GLU AAZA 841  1 ? 24 
HELX_P HELX_P17 AB8 ASN A 302 ? LEU A 323 ? ASN AAZA 844  LEU AAZA 865  1 ? 22 
HELX_P HELX_P18 AB9 ASN A 325 ? SER A 338 ? ASN AAZA 867  SER AAZA 880  1 ? 14 
HELX_P HELX_P19 AC1 SER A 338 ? ARG A 343 ? SER AAZA 880  ARG AAZA 885  1 ? 6  
HELX_P HELX_P20 AC2 LEU A 344 ? GLU A 349 ? LEU AAZA 886  GLU AAZA 891  1 ? 6  
HELX_P HELX_P21 AC3 PRO A 352 ? ILE A 380 ? PRO AAZA 894  ILE AAZA 922  1 ? 29 
HELX_P HELX_P22 AC4 PHE A 388 ? GLY A 401 ? PHE AAZA 930  GLY AAZA 943  1 ? 14 
HELX_P HELX_P23 AC5 PHE A 416 ? TYR A 432 ? PHE AAZA 958  TYR AAZA 974  1 ? 17 
HELX_P HELX_P24 AC6 GLU A 442 ? ASN A 451 ? GLU AAZA 984  ASN AAZA 993  1 ? 10 
HELX_P HELX_P25 AC7 MET A 459 ? GLU A 475 ? MET AAZA 1001 GLU AAZA 1017 1 ? 17 
HELX_P HELX_P26 AC8 GLY C 36  ? GLN C 46  ? GLY R    15   GLN R    25   1 ? 11 
HELX_P HELX_P27 AC9 ILE C 57  ? SER C 60  ? ILE R    36   SER R    39   5 ? 4  
HELX_P HELX_P28 AD1 TYR C 85  ? ALA C 87  ? TYR R    64   ALA R    66   5 ? 3  
HELX_P HELX_P29 AD2 MET C 88  ? THR C 95  ? MET R    67   THR R    74   1 ? 8  
HELX_P HELX_P30 AD3 ASN C 107 ? ASP C 113 ? ASN R    86   ASP R    92   1 ? 7  
HELX_P HELX_P31 AD4 ASP C 113 ? ASP C 126 ? ASP R    92   ASP R    105  1 ? 14 
HELX_P HELX_P32 AD5 ASP C 147 ? GLY C 159 ? ASP R    126  GLY R    138  1 ? 13 
HELX_P HELX_P33 AD6 LYS C 168 ? ARG C 170 ? LYS R    147  ARG R    149  5 ? 3  
HELX_P HELX_P34 AD7 GLY C 172 ? ARG C 185 ? GLY R    151  ARG R    164  1 ? 14 
HELX_P HELX_P35 AD8 ASP D 61  ? ARG D 64  ? ASP N    61   ARG N    64   5 ? 4  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? B CYS 22 SG ? ? ? 1_555 B CYS 100 SG ? ? C CYS 22 C CYS 100 1_555 ? ? ? ? ? ? ? 2.018 ? ? 
disulf2 disulf ? ? D CYS 22 SG ? ? ? 1_555 D CYS 95  SG ? ? N CYS 22 N CYS 95  1_555 ? ? ? ? ? ? ? 2.014 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          PRO 
_struct_mon_prot_cis.label_seq_id           382 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           PRO 
_struct_mon_prot_cis.auth_seq_id            924 
_struct_mon_prot_cis.auth_asym_id           AAZA 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    383 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     925 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    AAZA 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       23.26 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 6 ? 
AA7 ? 2 ? 
AA8 ? 3 ? 
AA9 ? 5 ? 
AB1 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA6 4 5 ? parallel      
AA6 5 6 ? parallel      
AA7 1 2 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 44  ? PHE A 46  ? ILE AAZA 586 PHE AAZA 588 
AA1 2 ILE A 59  ? GLY A 62  ? ILE AAZA 601 GLY AAZA 604 
AA1 3 ILE A 414 ? ASN A 415 ? ILE AAZA 956 ASN AAZA 957 
AA2 1 LYS A 407 ? ARG A 408 ? LYS AAZA 949 ARG AAZA 950 
AA2 2 LYS A 411 ? GLU A 412 ? LYS AAZA 953 GLU AAZA 954 
AA3 1 GLN B 3   ? LEU B 4   ? GLN C    3   LEU C    4   
AA3 2 ALA B 24  ? SER B 25  ? ALA C    24  SER C    25  
AA4 1 THR B 62  ? TYR B 64  ? THR C    62  TYR C    64  
AA4 2 GLU B 46  ? THR B 53  ? GLU C    46  THR C    53  
AA4 3 ILE B 31  ? ARG B 38  ? ILE C    31  ARG C    38  
AA4 4 TYR B 99  ? CYS B 100 ? TYR C    99  CYS C    100 
AA5 1 THR B 62  ? TYR B 64  ? THR C    62  TYR C    64  
AA5 2 GLU B 46  ? THR B 53  ? GLU C    46  THR C    53  
AA5 3 ILE B 31  ? ARG B 38  ? ILE C    31  ARG C    38  
AA5 4 LYS B 103 ? ARG B 105 ? LYS C    103 ARG C    105 
AA6 1 ARG C 62  ? ILE C 67  ? ARG R    41  ILE R    46  
AA6 2 GLU C 70  ? ASP C 78  ? GLU R    49  ASP R    57  
AA6 3 THR C 23  ? GLY C 31  ? THR R    2   GLY R    10  
AA6 4 GLY C 98  ? ALA C 104 ? GLY R    77  ALA R    83  
AA6 5 MET C 132 ? LYS C 138 ? MET R    111 LYS R    117 
AA6 6 PHE C 162 ? SER C 166 ? PHE R    141 SER R    145 
AA7 1 VAL D 12  ? GLN D 13  ? VAL N    12  GLN N    13  
AA7 2 VAL D 112 ? SER D 113 ? VAL N    112 SER N    113 
AA8 1 ARG D 19  ? LEU D 20  ? ARG N    19  LEU N    20  
AA8 2 LEU D 78  ? MET D 82  ? LEU N    78  MET N    82  
AA8 3 PHE D 67  ? LYS D 71  ? PHE N    67  LYS N    71  
AA9 1 ALA D 57  ? TYR D 59  ? ALA N    57  TYR N    59  
AA9 2 GLU D 46  ? ILE D 51  ? GLU N    46  ILE N    51  
AA9 3 LEU D 33  ? GLN D 39  ? LEU N    33  GLN N    39  
AA9 4 ALA D 91  ? ILE D 98  ? ALA N    91  ILE N    98  
AA9 5 ASP D 102 ? TYR D 103 ? ASP N    102 TYR N    103 
AB1 1 ALA D 57  ? TYR D 59  ? ALA N    57  TYR N    59  
AB1 2 GLU D 46  ? ILE D 51  ? GLU N    46  ILE N    51  
AB1 3 LEU D 33  ? GLN D 39  ? LEU N    33  GLN N    39  
AB1 4 ALA D 91  ? ILE D 98  ? ALA N    91  ILE N    98  
AB1 5 THR D 108 ? VAL D 110 ? THR N    108 VAL N    110 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 45  ? N ILE AAZA 587 O LYS A 60  ? O LYS AAZA 602 
AA1 2 3 N GLY A 62  ? N GLY AAZA 604 O ILE A 414 ? O ILE AAZA 956 
AA2 1 2 N ARG A 408 ? N ARG AAZA 950 O LYS A 411 ? O LYS AAZA 953 
AA3 1 2 N GLN B 3   ? N GLN C    3   O SER B 25  ? O SER C    25  
AA4 1 2 O ASN B 63  ? O ASN C    63  N THR B 50  ? N THR C    50  
AA4 2 3 O ALA B 49  ? O ALA C    49  N TRP B 36  ? N TRP C    36  
AA4 3 4 N TYR B 37  ? N TYR C    37  O TYR B 99  ? O TYR C    99  
AA5 1 2 O ASN B 63  ? O ASN C    63  N THR B 50  ? N THR C    50  
AA5 2 3 O ALA B 49  ? O ALA C    49  N TRP B 36  ? N TRP C    36  
AA5 3 4 N VAL B 33  ? N VAL C    33  O LYS B 103 ? O LYS C    103 
AA6 1 2 N LYS C 63  ? N LYS R    42  O LEU C 74  ? O LEU R    53  
AA6 2 3 O LEU C 77  ? O LEU R    56  N LEU C 27  ? N LEU R    6   
AA6 3 4 N VAL C 30  ? N VAL R    9   O VAL C 102 ? O VAL R    81  
AA6 4 5 N PHE C 103 ? N PHE R    82  O ASN C 137 ? O ASN R    116 
AA6 5 6 N GLY C 136 ? N GLY R    115 O THR C 165 ? O THR R    144 
AA7 1 2 N VAL D 12  ? N VAL N    12  O SER D 113 ? O SER N    113 
AA8 1 2 N LEU D 20  ? N LEU N    20  O LEU D 80  ? O LEU N    80  
AA8 2 3 O GLN D 81  ? O GLN N    81  N THR D 68  ? N THR N    68  
AA9 1 2 O ASN D 58  ? O ASN N    58  N ARG D 50  ? N ARG N    50  
AA9 2 3 O ALA D 49  ? O ALA N    49  N TRP D 36  ? N TRP N    36  
AA9 3 4 N TYR D 37  ? N TYR N    37  O TYR D 94  ? O TYR N    94  
AA9 4 5 N LEU D 97  ? N LEU N    97  O TYR D 103 ? O TYR N    103 
AB1 1 2 O ASN D 58  ? O ASN N    58  N ARG D 50  ? N ARG N    50  
AB1 2 3 O ALA D 49  ? O ALA N    49  N TRP D 36  ? N TRP N    36  
AB1 3 4 N TYR D 37  ? N TYR N    37  O TYR D 94  ? O TYR N    94  
AB1 4 5 N TYR D 93  ? N TYR N    93  O THR D 108 ? O THR N    108 
# 
_atom_sites.entry_id                    8BE5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   0.008059 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008059 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.002446 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C   ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N   ? ? 6.96715 ?       ? ? 11.43723 ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O   ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O1- ? ? 5.12366 3.84317 ? ? 3.49406  27.47979 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S   ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . PRO A 1 28  ? 47.15700 37.71400 113.69400 1.000 123.08000 ?  570  PRO AAZA N   1 
ATOM   2    C CA  . PRO A 1 28  ? 48.48300 38.35100 113.80200 1.000 118.95000 ?  570  PRO AAZA CA  1 
ATOM   3    C C   . PRO A 1 28  ? 48.45000 39.86500 113.62200 1.000 112.23000 ?  570  PRO AAZA C   1 
ATOM   4    O O   . PRO A 1 28  ? 47.40700 40.48600 113.42600 1.000 106.40000 ?  570  PRO AAZA O   1 
ATOM   5    C CB  . PRO A 1 28  ? 49.30300 37.71300 112.67300 1.000 109.55000 ?  570  PRO AAZA CB  1 
ATOM   6    C CG  . PRO A 1 28  ? 48.52100 36.56500 112.21000 1.000 114.70000 ?  570  PRO AAZA CG  1 
ATOM   7    C CD  . PRO A 1 28  ? 47.07100 36.82900 112.52400 1.000 118.06000 ?  570  PRO AAZA CD  1 
ATOM   8    N N   . SER A 1 29  ? 49.64000 40.46700 113.68300 1.000 114.45000 ?  571  SER AAZA N   1 
ATOM   9    C CA  . SER A 1 29  ? 49.74600 41.94600 113.58900 1.000 124.23000 ?  571  SER AAZA CA  1 
ATOM   10   C C   . SER A 1 29  ? 49.36000 42.43500 112.19700 1.000 123.95000 ?  571  SER AAZA C   1 
ATOM   11   O O   . SER A 1 29  ? 49.54400 41.67700 111.23300 1.000 122.00000 ?  571  SER AAZA O   1 
ATOM   12   C CB  . SER A 1 29  ? 51.13200 42.40500 113.92900 1.000 129.88000 ?  571  SER AAZA CB  1 
ATOM   13   O OG  . SER A 1 29  ? 51.35000 43.72600 113.45600 1.000 135.01000 ?  571  SER AAZA OG  1 
ATOM   14   N N   . ALA A 1 30  ? 48.88900 43.67700 112.10800 1.000 123.22000 ?  572  ALA AAZA N   1 
ATOM   15   C CA  . ALA A 1 30  ? 48.44700 44.23200 110.81200 1.000 125.91000 ?  572  ALA AAZA CA  1 
ATOM   16   C C   . ALA A 1 30  ? 49.64000 44.85600 110.08800 1.000 131.10000 ?  572  ALA AAZA C   1 
ATOM   17   O O   . ALA A 1 30  ? 49.44900 45.34500 108.96200 1.000 124.00000 ?  572  ALA AAZA O   1 
ATOM   18   C CB  . ALA A 1 30  ? 47.36800 45.25100 111.05800 1.000 120.11000 ?  572  ALA AAZA CB  1 
ATOM   19   N N   . ASP A 1 31  ? 50.82100 44.83800 110.70900 1.000 134.57000 ?  573  ASP AAZA N   1 
ATOM   20   C CA  . ASP A 1 31  ? 51.98600 45.52600 110.09300 1.000 134.53000 ?  573  ASP AAZA CA  1 
ATOM   21   C C   . ASP A 1 31  ? 53.12500 44.57600 109.72000 1.000 128.45000 ?  573  ASP AAZA C   1 
ATOM   22   O O   . ASP A 1 31  ? 53.77500 44.83100 108.69400 1.000 124.32000 ?  573  ASP AAZA O   1 
ATOM   23   C CB  . ASP A 1 31  ? 52.55400 46.59700 111.02400 1.000 137.08000 ?  573  ASP AAZA CB  1 
ATOM   24   C CG  . ASP A 1 31  ? 51.51800 47.62900 111.43000 1.000 143.69000 ?  573  ASP AAZA CG  1 
ATOM   25   O OD1 . ASP A 1 31  ? 50.96600 48.28800 110.52800 1.000 145.40000 ?  573  ASP AAZA OD1 1 
ATOM   26   O OD2 . ASP A 1 31  ? 51.26600 47.76000 112.64300 1.000 145.11000 ?  573  ASP AAZA OD2 1 
ATOM   27   N N   . VAL A 1 32  ? 53.37000 43.53300 110.51600 1.000 127.93000 ?  574  VAL AAZA N   1 
ATOM   28   C CA  . VAL A 1 32  ? 54.51500 42.68800 110.17700 1.000 126.54000 ?  574  VAL AAZA CA  1 
ATOM   29   C C   . VAL A 1 32  ? 53.98500 41.60000 109.24400 1.000 123.44000 ?  574  VAL AAZA C   1 
ATOM   30   O O   . VAL A 1 32  ? 54.74700 40.75400 108.76100 1.000 121.00000 ?  574  VAL AAZA O   1 
ATOM   31   C CB  . VAL A 1 32  ? 55.20300 42.08600 111.41800 1.000 120.77000 ?  574  VAL AAZA CB  1 
ATOM   32   C CG1 . VAL A 1 32  ? 55.76800 43.19900 112.26100 1.000 121.55000 ?  574  VAL AAZA CG1 1 
ATOM   33   C CG2 . VAL A 1 32  ? 54.22300 41.23300 112.23600 1.000 117.64000 ?  574  VAL AAZA CG2 1 
ATOM   34   N N   . TYR A 1 33  ? 52.68200 41.62500 108.96800 1.000 118.17000 ?  575  TYR AAZA N   1 
ATOM   35   C CA  . TYR A 1 33  ? 52.06500 40.67600 108.04600 1.000 110.20000 ?  575  TYR AAZA CA  1 
ATOM   36   C C   . TYR A 1 33  ? 50.90900 41.42100 107.38500 1.000 114.56000 ?  575  TYR AAZA C   1 
ATOM   37   O O   . TYR A 1 33  ? 49.87700 41.65300 108.02100 1.000 116.40000 ?  575  TYR AAZA O   1 
ATOM   38   C CB  . TYR A 1 33  ? 51.60300 39.42400 108.77400 1.000 106.27000 ?  575  TYR AAZA CB  1 
ATOM   39   C CG  . TYR A 1 33  ? 51.13000 38.31500 107.87700 1.000 101.82000 ?  575  TYR AAZA CG  1 
ATOM   40   C CD1 . TYR A 1 33  ? 52.04000 37.51200 107.20300 1.000 104.60000 ?  575  TYR AAZA CD1 1 
ATOM   41   C CD2 . TYR A 1 33  ? 49.77700 38.04200 107.73100 1.000 100.13000 ?  575  TYR AAZA CD2 1 
ATOM   42   C CE1 . TYR A 1 33  ? 51.62000 36.48000 106.38700 1.000 102.09000 ?  575  TYR AAZA CE1 1 
ATOM   43   C CE2 . TYR A 1 33  ? 49.34300 37.00800 106.91800 1.000 103.49000 ?  575  TYR AAZA CE2 1 
ATOM   44   C CZ  . TYR A 1 33  ? 50.27300 36.23100 106.24100 1.000 103.84000 ?  575  TYR AAZA CZ  1 
ATOM   45   O OH  . TYR A 1 33  ? 49.85500 35.20700 105.41200 1.000 101.32000 ?  575  TYR AAZA OH  1 
ATOM   46   N N   . ARG A 1 34  ? 51.09600 41.79500 106.11400 1.000 110.04000 ?  576  ARG AAZA N   1 
ATOM   47   C CA  . ARG A 1 34  ? 50.17000 42.70200 105.45200 1.000 97.49000  ?  576  ARG AAZA CA  1 
ATOM   48   C C   . ARG A 1 34  ? 48.86400 42.03600 105.04700 1.000 96.88000  ?  576  ARG AAZA C   1 
ATOM   49   O O   . ARG A 1 34  ? 47.87400 42.74000 104.82300 1.000 94.86000  ?  576  ARG AAZA O   1 
ATOM   50   C CB  . ARG A 1 34  ? 50.83500 43.29300 104.23600 1.000 89.95000  ?  576  ARG AAZA CB  1 
ATOM   51   C CG  . ARG A 1 34  ? 52.13400 43.94600 104.52000 1.000 96.72000  ?  576  ARG AAZA CG  1 
ATOM   52   C CD  . ARG A 1 34  ? 52.48900 44.73200 103.29800 1.000 107.85000 ?  576  ARG AAZA CD  1 
ATOM   53   N NE  . ARG A 1 34  ? 52.89400 43.90000 102.16900 1.000 106.20000 ?  576  ARG AAZA NE  1 
ATOM   54   C CZ  . ARG A 1 34  ? 52.80800 44.30200 100.91100 1.000 99.15000  ?  576  ARG AAZA CZ  1 
ATOM   55   N NH1 . ARG A 1 34  ? 52.18500 45.42700 100.60000 1.000 91.76000  ?  576  ARG AAZA NH1 1 
ATOM   56   N NH2 . ARG A 1 34  ? 53.33900 43.54900 99.94500  1.000 92.67000  ?  576  ARG AAZA NH2 1 
ATOM   57   N N   . PHE A 1 35  ? 48.88300 40.70700 104.95700 1.000 94.78000  ?  577  PHE AAZA N   1 
ATOM   58   C CA  . PHE A 1 35  ? 47.68500 39.93700 104.54800 1.000 93.49000  ?  577  PHE AAZA CA  1 
ATOM   59   C C   . PHE A 1 35  ? 46.69800 39.85600 105.70800 1.000 106.38000 ?  577  PHE AAZA C   1 
ATOM   60   O O   . PHE A 1 35  ? 45.77300 39.03200 105.65200 1.000 107.16000 ?  577  PHE AAZA O   1 
ATOM   61   C CB  . PHE A 1 35  ? 48.12300 38.56300 104.04800 1.000 95.63000  ?  577  PHE AAZA CB  1 
ATOM   62   C CG  . PHE A 1 35  ? 49.03000 38.59400 102.84500 1.000 101.35000 ?  577  PHE AAZA CG  1 
ATOM   63   C CD1 . PHE A 1 35  ? 48.54400 38.94900 101.59800 1.000 92.14000  ?  577  PHE AAZA CD1 1 
ATOM   64   C CD2 . PHE A 1 35  ? 50.37700 38.30000 102.96500 1.000 100.24000 ?  577  PHE AAZA CD2 1 
ATOM   65   C CE1 . PHE A 1 35  ? 49.37900 38.98300 100.49400 1.000 84.77000  ?  577  PHE AAZA CE1 1 
ATOM   66   C CE2 . PHE A 1 35  ? 51.21300 38.34000 101.86100 1.000 96.86000  ?  577  PHE AAZA CE2 1 
ATOM   67   C CZ  . PHE A 1 35  ? 50.71300 38.68000 100.62800 1.000 88.34000  ?  577  PHE AAZA CZ  1 
ATOM   68   N N   . ALA A 1 36  ? 46.90800 40.68200 106.73200 1.000 111.68000 ?  578  ALA AAZA N   1 
ATOM   69   C CA  . ALA A 1 36  ? 45.99800 40.70000 107.89700 1.000 105.37000 ?  578  ALA AAZA CA  1 
ATOM   70   C C   . ALA A 1 36  ? 44.97600 41.83200 107.89100 1.000 117.18000 ?  578  ALA AAZA C   1 
ATOM   71   O O   . ALA A 1 36  ? 43.90300 41.66200 108.49500 1.000 120.44000 ?  578  ALA AAZA O   1 
ATOM   72   C CB  . ALA A 1 36  ? 46.82200 40.94000 109.12800 1.000 101.48000 ?  578  ALA AAZA CB  1 
ATOM   73   N N   . GLU A 1 37  ? 45.31300 42.94000 107.23200 1.000 112.73000 ?  579  GLU AAZA N   1 
ATOM   74   C CA  . GLU A 1 37  ? 44.40800 44.11500 107.19800 1.000 110.13000 ?  579  GLU AAZA CA  1 
ATOM   75   C C   . GLU A 1 37  ? 43.00900 43.55000 106.97300 1.000 117.56000 ?  579  GLU AAZA C   1 
ATOM   76   O O   . GLU A 1 37  ? 42.81500 42.82500 105.98600 1.000 120.79000 ?  579  GLU AAZA O   1 
ATOM   77   C CB  . GLU A 1 37  ? 44.83500 45.01100 106.03900 1.000 117.37000 ?  579  GLU AAZA CB  1 
ATOM   78   C CG  . GLU A 1 37  ? 44.02100 46.28600 105.93400 1.000 125.90000 ?  579  GLU AAZA CG  1 
ATOM   79   C CD  . GLU A 1 37  ? 44.12200 47.19100 107.14900 1.000 128.78000 ?  579  GLU AAZA CD  1 
ATOM   80   O OE1 . GLU A 1 37  ? 45.24900 47.60500 107.48300 1.000 126.01000 ?  579  GLU AAZA OE1 1 
ATOM   81   O OE2 . GLU A 1 37  ? 43.07200 47.48200 107.75600 1.000 130.14000 ?  579  GLU AAZA OE2 1 
ATOM   82   N N   . PRO A 1 38  ? 42.02900 43.85800 107.84100 1.000 119.87000 ?  580  PRO AAZA N   1 
ATOM   83   C CA  . PRO A 1 38  ? 40.69800 43.26400 107.72700 1.000 116.84000 ?  580  PRO AAZA CA  1 
ATOM   84   C C   . PRO A 1 38  ? 39.97800 43.62800 106.42300 1.000 113.06000 ?  580  PRO AAZA C   1 
ATOM   85   O O   . PRO A 1 38  ? 40.28800 44.65200 105.85200 1.000 108.91000 ?  580  PRO AAZA O   1 
ATOM   86   C CB  . PRO A 1 38  ? 39.94800 43.88000 108.91600 1.000 119.22000 ?  580  PRO AAZA CB  1 
ATOM   87   C CG  . PRO A 1 38  ? 40.70100 45.15500 109.21500 1.000 113.08000 ?  580  PRO AAZA CG  1 
ATOM   88   C CD  . PRO A 1 38  ? 42.14700 44.79700 108.95400 1.000 112.77000 ?  580  PRO AAZA CD  1 
ATOM   89   N N   . ASP A 1 39  ? 39.04200 42.77800 105.99200 1.000 108.84000 ?  581  ASP AAZA N   1 
ATOM   90   C CA  . ASP A 1 39  ? 38.25400 43.06500 104.76800 1.000 100.56000 ?  581  ASP AAZA CA  1 
ATOM   91   C C   . ASP A 1 39  ? 37.55100 44.40800 104.95200 1.000 101.40000 ?  581  ASP AAZA C   1 
ATOM   92   O O   . ASP A 1 39  ? 37.43200 44.85200 106.10500 1.000 109.13000 ?  581  ASP AAZA O   1 
ATOM   93   C CB  . ASP A 1 39  ? 37.23800 41.96100 104.47200 1.000 92.85000  ?  581  ASP AAZA CB  1 
ATOM   94   C CG  . ASP A 1 39  ? 37.83500 40.56600 104.43500 1.000 101.97000 ?  581  ASP AAZA CG  1 
ATOM   95   O OD1 . ASP A 1 39  ? 39.02600 40.43100 104.76300 1.000 102.47000 ?  581  ASP AAZA OD1 1 
ATOM   96   O OD2 . ASP A 1 39  ? 37.10500 39.62800 104.06500 1.000 101.15000 ?  581  ASP AAZA OD2 1 
ATOM   97   N N   . SER A 1 40  ? 37.08900 45.01100 103.85800 1.000 100.67000 ?  582  SER AAZA N   1 
ATOM   98   C CA  . SER A 1 40  ? 36.41700 46.30400 103.93300 1.000 100.17000 ?  582  SER AAZA CA  1 
ATOM   99   C C   . SER A 1 40  ? 36.02300 46.71600 102.52000 1.000 104.39000 ?  582  SER AAZA C   1 
ATOM   100  O O   . SER A 1 40  ? 36.49300 46.14600 101.52900 1.000 103.76000 ?  582  SER AAZA O   1 
ATOM   101  C CB  . SER A 1 40  ? 37.29100 47.37200 104.56600 1.000 100.11000 ?  582  SER AAZA CB  1 
ATOM   102  O OG  . SER A 1 40  ? 38.30800 47.76900 103.67900 1.000 97.61000  ?  582  SER AAZA OG  1 
ATOM   103  N N   . GLU A 1 41  ? 35.16200 47.72700 102.43300 1.000 107.01000 ?  583  GLU AAZA N   1 
ATOM   104  C CA  . GLU A 1 41  ? 34.64400 48.13500 101.13400 1.000 106.57000 ?  583  GLU AAZA CA  1 
ATOM   105  C C   . GLU A 1 41  ? 35.64800 48.92400 100.32400 1.000 100.82000 ?  583  GLU AAZA C   1 
ATOM   106  O O   . GLU A 1 41  ? 35.30000 49.40900 99.24700  1.000 105.92000 ?  583  GLU AAZA O   1 
ATOM   107  C CB  . GLU A 1 41  ? 33.37100 48.95400 101.29600 1.000 112.62000 ?  583  GLU AAZA CB  1 
ATOM   108  C CG  . GLU A 1 41  ? 32.30600 48.21600 102.03700 1.000 123.50000 ?  583  GLU AAZA CG  1 
ATOM   109  C CD  . GLU A 1 41  ? 30.99600 48.94300 101.99400 1.000 141.94000 ?  583  GLU AAZA CD  1 
ATOM   110  O OE1 . GLU A 1 41  ? 30.97400 50.13600 102.38000 1.000 146.56000 ?  583  GLU AAZA OE1 1 
ATOM   111  O OE2 . GLU A 1 41  ? 29.99600 48.32100 101.56600 1.000 146.55000 ?  583  GLU AAZA OE2 1 
ATOM   112  N N   . GLU A 1 42  ? 36.86300 49.08900 100.82400 1.000 97.06000  ?  584  GLU AAZA N   1 
ATOM   113  C CA  . GLU A 1 42  ? 37.97100 49.61000 100.04100 1.000 97.46000  ?  584  GLU AAZA CA  1 
ATOM   114  C C   . GLU A 1 42  ? 39.07300 48.56600 99.84500  1.000 92.50000  ?  584  GLU AAZA C   1 
ATOM   115  O O   . GLU A 1 42  ? 40.17900 48.90200 99.41500  1.000 86.53000  ?  584  GLU AAZA O   1 
ATOM   116  C CB  . GLU A 1 42  ? 38.49500 50.89000 100.70000 1.000 101.07000 ?  584  GLU AAZA CB  1 
ATOM   117  C CG  . GLU A 1 42  ? 38.77700 50.74800 102.20000 1.000 108.31000 ?  584  GLU AAZA CG  1 
ATOM   118  C CD  . GLU A 1 42  ? 38.70000 52.07400 102.96200 1.000 120.60000 ?  584  GLU AAZA CD  1 
ATOM   119  O OE1 . GLU A 1 42  ? 37.62500 52.72200 102.94600 1.000 125.01000 ?  584  GLU AAZA OE1 1 
ATOM   120  O OE2 . GLU A 1 42  ? 39.72200 52.45500 103.59000 1.000 117.89000 ?  584  GLU AAZA OE2 1 
ATOM   121  N N   . ASN A 1 43  ? 38.77800 47.31900 100.20900 1.000 92.54000  ?  585  ASN AAZA N   1 
ATOM   122  C CA  . ASN A 1 43  ? 39.80400 46.25100 100.11600 1.000 89.69000  ?  585  ASN AAZA CA  1 
ATOM   123  C C   . ASN A 1 43  ? 39.29900 45.14000 99.20000  1.000 89.46000  ?  585  ASN AAZA C   1 
ATOM   124  O O   . ASN A 1 43  ? 40.12200 44.56800 98.47200  1.000 86.66000  ?  585  ASN AAZA O   1 
ATOM   125  C CB  . ASN A 1 43  ? 40.15600 45.67300 101.48700 1.000 91.61000  ?  585  ASN AAZA CB  1 
ATOM   126  C CG  . ASN A 1 43  ? 40.97300 46.61300 102.34400 1.000 98.37000  ?  585  ASN AAZA CG  1 
ATOM   127  O OD1 . ASN A 1 43  ? 40.58700 46.93200 103.46600 1.000 107.74000 ?  585  ASN AAZA OD1 1 
ATOM   128  N ND2 . ASN A 1 43  ? 42.11600 47.04300 101.83500 1.000 95.95000  ?  585  ASN AAZA ND2 1 
ATOM   129  N N   . ILE A 1 44  ? 37.99900 44.85200 99.24000  1.000 86.86000  ?  586  ILE AAZA N   1 
ATOM   130  C CA  . ILE A 1 44  ? 37.48500 43.70400 98.44200  1.000 82.73000  ?  586  ILE AAZA CA  1 
ATOM   131  C C   . ILE A 1 44  ? 35.97600 43.82900 98.23500  1.000 81.49000  ?  586  ILE AAZA C   1 
ATOM   132  O O   . ILE A 1 44  ? 35.28700 44.22200 99.18600  1.000 87.19000  ?  586  ILE AAZA O   1 
ATOM   133  C CB  . ILE A 1 44  ? 37.86800 42.37800 99.12800  1.000 81.45000  ?  586  ILE AAZA CB  1 
ATOM   134  C CG1 . ILE A 1 44  ? 37.53700 41.16500 98.25700  1.000 82.47000  ?  586  ILE AAZA CG1 1 
ATOM   135  C CG2 . ILE A 1 44  ? 37.23100 42.27600 100.50500 1.000 86.68000  ?  586  ILE AAZA CG2 1 
ATOM   136  C CD1 . ILE A 1 44  ? 38.11600 39.87300 98.77400  1.000 83.99000  ?  586  ILE AAZA CD1 1 
ATOM   137  N N   . ILE A 1 45  ? 35.49500 43.52800 97.02900  1.000 83.23000  ?  587  ILE AAZA N   1 
ATOM   138  C CA  . ILE A 1 45  ? 34.06900 43.53000 96.73200  1.000 83.31000  ?  587  ILE AAZA CA  1 
ATOM   139  C C   . ILE A 1 45  ? 33.69800 42.15700 96.20600  1.000 84.16000  ?  587  ILE AAZA C   1 
ATOM   140  O O   . ILE A 1 45  ? 34.41700 41.58900 95.37700  1.000 89.09000  ?  587  ILE AAZA O   1 
ATOM   141  C CB  . ILE A 1 45  ? 33.70300 44.59900 95.68500  1.000 82.06000  ?  587  ILE AAZA CB  1 
ATOM   142  C CG1 . ILE A 1 45  ? 34.32300 45.93400 96.04400  1.000 83.83000  ?  587  ILE AAZA CG1 1 
ATOM   143  C CG2 . ILE A 1 45  ? 32.20300 44.69900 95.50400  1.000 91.17000  ?  587  ILE AAZA CG2 1 
ATOM   144  C CD1 . ILE A 1 45  ? 33.87900 47.01700 95.13600  1.000 89.63000  ?  587  ILE AAZA CD1 1 
ATOM   145  N N   . PHE A 1 46  ? 32.57600 41.63100 96.65900  1.000 81.88000  ?  588  PHE AAZA N   1 
ATOM   146  C CA  . PHE A 1 46  ? 32.15900 40.32000 96.20300  1.000 86.82000  ?  588  PHE AAZA CA  1 
ATOM   147  C C   . PHE A 1 46  ? 31.01500 40.48100 95.21600  1.000 91.71000  ?  588  PHE AAZA C   1 
ATOM   148  O O   . PHE A 1 46  ? 30.46100 41.57200 95.05600  1.000 93.74000  ?  588  PHE AAZA O   1 
ATOM   149  C CB  . PHE A 1 46  ? 31.79200 39.42800 97.39300  1.000 82.58000  ?  588  PHE AAZA CB  1 
ATOM   150  C CG  . PHE A 1 46  ? 32.95100 39.16900 98.30500  1.000 82.50000  ?  588  PHE AAZA CG  1 
ATOM   151  C CD1 . PHE A 1 46  ? 33.39400 40.14800 99.18400  1.000 84.74000  ?  588  PHE AAZA CD1 1 
ATOM   152  C CD2 . PHE A 1 46  ? 33.63500 37.96800 98.25400  1.000 87.38000  ?  588  PHE AAZA CD2 1 
ATOM   153  C CE1 . PHE A 1 46  ? 34.48800 39.92900 100.00900 1.000 84.24000  ?  588  PHE AAZA CE1 1 
ATOM   154  C CE2 . PHE A 1 46  ? 34.73000 37.73600 99.08500  1.000 90.15000  ?  588  PHE AAZA CE2 1 
ATOM   155  C CZ  . PHE A 1 46  ? 35.15400 38.71900 99.96400  1.000 87.40000  ?  588  PHE AAZA CZ  1 
ATOM   156  N N   . GLU A 1 47  ? 30.70600 39.40200 94.50400  1.000 92.47000  ?  589  GLU AAZA N   1 
ATOM   157  C CA  . GLU A 1 47  ? 29.59600 39.45700 93.57300  1.000 104.07000 ?  589  GLU AAZA CA  1 
ATOM   158  C C   . GLU A 1 47  ? 28.33300 39.09000 94.36200  1.000 113.75000 ?  589  GLU AAZA C   1 
ATOM   159  O O   . GLU A 1 47  ? 28.40500 38.75400 95.54900  1.000 112.25000 ?  589  GLU AAZA O   1 
ATOM   160  C CB  . GLU A 1 47  ? 29.86000 38.51700 92.39500  1.000 107.32000 ?  589  GLU AAZA CB  1 
ATOM   161  C CG  . GLU A 1 47  ? 29.29600 38.94900 91.02100  1.000 115.70000 ?  589  GLU AAZA CG  1 
ATOM   162  C CD  . GLU A 1 47  ? 30.13300 40.06600 90.35200  1.000 115.07000 ?  589  GLU AAZA CD  1 
ATOM   163  O OE1 . GLU A 1 47  ? 31.37700 39.90100 90.28000  1.000 108.98000 ?  589  GLU AAZA OE1 1 
ATOM   164  O OE2 . GLU A 1 47  ? 29.56600 41.08900 89.88500  1.000 125.96000 -1 589  GLU AAZA OE2 1 
ATOM   165  N N   . GLU A 1 48  ? 27.15400 39.15000 93.73600  1.000 122.21000 ?  590  GLU AAZA N   1 
ATOM   166  C CA  . GLU A 1 48  ? 25.91500 38.83400 94.44600  1.000 131.86000 ?  590  GLU AAZA CA  1 
ATOM   167  C C   . GLU A 1 48  ? 25.22400 37.59500 93.87900  1.000 138.11000 ?  590  GLU AAZA C   1 
ATOM   168  O O   . GLU A 1 48  ? 25.36900 37.26900 92.69200  1.000 133.17000 ?  590  GLU AAZA O   1 
ATOM   169  C CB  . GLU A 1 48  ? 24.95100 40.02900 94.44900  1.000 127.59000 ?  590  GLU AAZA CB  1 
ATOM   170  C CG  . GLU A 1 48  ? 25.30400 41.09200 95.50200  1.000 135.14000 ?  590  GLU AAZA CG  1 
ATOM   171  C CD  . GLU A 1 48  ? 25.32300 40.55300 96.95500  1.000 142.90000 ?  590  GLU AAZA CD  1 
ATOM   172  O OE1 . GLU A 1 48  ? 26.36400 40.01000 97.40000  1.000 138.72000 ?  590  GLU AAZA OE1 1 
ATOM   173  O OE2 . GLU A 1 48  ? 24.29800 40.69400 97.66300  1.000 146.64000 -1 590  GLU AAZA OE2 1 
ATOM   174  N N   . ASN A 1 49  ? 24.46900 36.92400 94.76600  1.000 137.61000 ?  591  ASN AAZA N   1 
ATOM   175  C CA  . ASN A 1 49  ? 23.82900 35.60900 94.56700  1.000 136.19000 ?  591  ASN AAZA CA  1 
ATOM   176  C C   . ASN A 1 49  ? 24.83200 34.48800 94.84800  1.000 136.42000 ?  591  ASN AAZA C   1 
ATOM   177  O O   . ASN A 1 49  ? 24.56700 33.58900 95.65400  1.000 138.64000 ?  591  ASN AAZA O   1 
ATOM   178  C CB  . ASN A 1 49  ? 23.23500 35.46400 93.15500  1.000 136.67000 ?  591  ASN AAZA CB  1 
ATOM   179  C CG  . ASN A 1 49  ? 22.76100 34.05400 92.85500  1.000 140.00000 ?  591  ASN AAZA CG  1 
ATOM   180  O OD1 . ASN A 1 49  ? 22.42100 33.28800 93.75900  1.000 144.91000 ?  591  ASN AAZA OD1 1 
ATOM   181  N ND2 . ASN A 1 49  ? 22.75100 33.69900 91.57600  1.000 133.57000 ?  591  ASN AAZA ND2 1 
ATOM   182  N N   . ALA A 1 54  ? 23.88400 28.64400 97.89300  1.000 113.82000 ?  596  ALA AAZA N   1 
ATOM   183  C CA  . ALA A 1 54  ? 24.48400 29.99300 98.01200  1.000 124.92000 ?  596  ALA AAZA CA  1 
ATOM   184  C C   . ALA A 1 54  ? 25.37100 30.03900 99.25900  1.000 127.95000 ?  596  ALA AAZA C   1 
ATOM   185  O O   . ALA A 1 54  ? 24.90700 30.53700 100.30000 1.000 121.96000 ?  596  ALA AAZA O   1 
ATOM   186  C CB  . ALA A 1 54  ? 23.40200 31.04400 98.05000  1.000 107.35000 ?  596  ALA AAZA CB  1 
ATOM   187  N N   . GLY A 1 55  ? 26.59700 29.52200 99.15000  1.000 127.74000 ?  597  GLY AAZA N   1 
ATOM   188  C CA  . GLY A 1 55  ? 27.52000 29.51200 100.29100 1.000 119.18000 ?  597  GLY AAZA CA  1 
ATOM   189  C C   . GLY A 1 55  ? 28.97600 29.34700 99.85100  1.000 118.91000 ?  597  GLY AAZA C   1 
ATOM   190  O O   . GLY A 1 55  ? 29.54700 28.29400 100.17100 1.000 116.51000 ?  597  GLY AAZA O   1 
ATOM   191  N N   . ILE A 1 56  ? 29.52600 30.27400 99.07700  1.000 124.64000 ?  598  ILE AAZA N   1 
ATOM   192  C CA  . ILE A 1 56  ? 30.97300 30.22700 98.73900  1.000 115.42000 ?  598  ILE AAZA CA  1 
ATOM   193  C C   . ILE A 1 56  ? 31.23400 31.59000 98.05900  1.000 103.88000 ?  598  ILE AAZA C   1 
ATOM   194  O O   . ILE A 1 56  ? 30.59300 31.83900 97.02700  1.000 101.06000 ?  598  ILE AAZA O   1 
ATOM   195  C CB  . ILE A 1 56  ? 31.27300 29.06300 97.79700  1.000 117.11000 ?  598  ILE AAZA CB  1 
ATOM   196  C CG1 . ILE A 1 56  ? 32.56100 29.28100 96.99800  1.000 110.79000 ?  598  ILE AAZA CG1 1 
ATOM   197  C CG2 . ILE A 1 56  ? 30.08400 28.78900 96.88800  1.000 111.74000 ?  598  ILE AAZA CG2 1 
ATOM   198  C CD1 . ILE A 1 56  ? 33.81100 29.30100 97.84500  1.000 102.89000 ?  598  ILE AAZA CD1 1 
ATOM   199  N N   . PRO A 1 57  ? 32.12300 32.47700 98.55000  1.000 98.75000  ?  599  PRO AAZA N   1 
ATOM   200  C CA  . PRO A 1 57  ? 32.14000 33.85300 98.02900  1.000 98.21000  ?  599  PRO AAZA CA  1 
ATOM   201  C C   . PRO A 1 57  ? 32.82900 33.95600 96.67400  1.000 99.91000  ?  599  PRO AAZA C   1 
ATOM   202  O O   . PRO A 1 57  ? 33.71700 33.16300 96.33400  1.000 98.58000  ?  599  PRO AAZA O   1 
ATOM   203  C CB  . PRO A 1 57  ? 32.92400 34.63200 99.09400  1.000 89.11000  ?  599  PRO AAZA CB  1 
ATOM   204  C CG  . PRO A 1 57  ? 33.02300 33.71200 100.26500 1.000 98.55000  ?  599  PRO AAZA CG  1 
ATOM   205  C CD  . PRO A 1 57  ? 33.01800 32.32300 99.70300  1.000 98.08000  ?  599  PRO AAZA CD  1 
ATOM   206  N N   . ILE A 1 58  ? 32.41900 34.96700 95.90200  1.000 92.83000  ?  600  ILE AAZA N   1 
ATOM   207  C CA  . ILE A 1 58  ? 32.95600 35.21500 94.56300  1.000 95.28000  ?  600  ILE AAZA CA  1 
ATOM   208  C C   . ILE A 1 58  ? 33.40800 36.66900 94.45100  1.000 91.60000  ?  600  ILE AAZA C   1 
ATOM   209  O O   . ILE A 1 58  ? 32.59600 37.59200 94.60300  1.000 90.51000  ?  600  ILE AAZA O   1 
ATOM   210  C CB  . ILE A 1 58  ? 31.93700 34.87500 93.46700  1.000 89.75000  ?  600  ILE AAZA CB  1 
ATOM   211  C CG1 . ILE A 1 58  ? 31.80800 33.36200 93.36500  1.000 89.47000  ?  600  ILE AAZA CG1 1 
ATOM   212  C CG2 . ILE A 1 58  ? 32.34200 35.49700 92.13700  1.000 80.06000  ?  600  ILE AAZA CG2 1 
ATOM   213  C CD1 . ILE A 1 58  ? 30.42300 32.90700 93.05800  1.000 100.07000 ?  600  ILE AAZA CD1 1 
ATOM   214  N N   . ILE A 1 59  ? 34.69200 36.86700 94.14600  1.000 84.24000  ?  601  ILE AAZA N   1 
ATOM   215  C CA  . ILE A 1 59  ? 35.30600 38.18700 94.19500  1.000 80.14000  ?  601  ILE AAZA CA  1 
ATOM   216  C C   . ILE A 1 59  ? 34.94800 38.98900 92.95600  1.000 85.77000  ?  601  ILE AAZA C   1 
ATOM   217  O O   . ILE A 1 59  ? 35.05500 38.49700 91.82100  1.000 87.43000  ?  601  ILE AAZA O   1 
ATOM   218  C CB  . ILE A 1 59  ? 36.82100 38.06800 94.33600  1.000 75.42000  ?  601  ILE AAZA CB  1 
ATOM   219  C CG1 . ILE A 1 59  ? 37.14100 37.30800 95.60400  1.000 80.93000  ?  601  ILE AAZA CG1 1 
ATOM   220  C CG2 . ILE A 1 59  ? 37.45400 39.42600 94.29900  1.000 74.61000  ?  601  ILE AAZA CG2 1 
ATOM   221  C CD1 . ILE A 1 59  ? 38.58100 37.25300 95.88100  1.000 86.22000  ?  601  ILE AAZA CD1 1 
ATOM   222  N N   . LYS A 1 60  ? 34.53800 40.23600 93.17100  1.000 80.33000  ?  602  LYS AAZA N   1 
ATOM   223  C CA  . LYS A 1 60  ? 34.30200 41.14000 92.06400  1.000 78.95000  ?  602  LYS AAZA CA  1 
ATOM   224  C C   . LYS A 1 60  ? 35.54500 41.96400 91.80900  1.000 80.81000  ?  602  LYS AAZA C   1 
ATOM   225  O O   . LYS A 1 60  ? 36.03600 42.03500 90.67800  1.000 84.48000  ?  602  LYS AAZA O   1 
ATOM   226  C CB  . LYS A 1 60  ? 33.10900 42.05200 92.34700  1.000 83.64000  ?  602  LYS AAZA CB  1 
ATOM   227  C CG  . LYS A 1 60  ? 32.68000 42.86700 91.14800  1.000 82.14000  ?  602  LYS AAZA CG  1 
ATOM   228  C CD  . LYS A 1 60  ? 31.53800 43.79900 91.45100  1.000 77.92000  ?  602  LYS AAZA CD  1 
ATOM   229  C CE  . LYS A 1 60  ? 31.01400 44.41900 90.17600  1.000 90.12000  ?  602  LYS AAZA CE  1 
ATOM   230  N NZ  . LYS A 1 60  ? 29.86400 45.34900 90.38400  1.000 98.17000  ?  602  LYS AAZA NZ  1 
ATOM   231  N N   . ALA A 1 61  ? 36.07800 42.57400 92.85700  1.000 78.40000  ?  603  ALA AAZA N   1 
ATOM   232  C CA  . ALA A 1 61  ? 37.29700 43.35300 92.74200  1.000 79.48000  ?  603  ALA AAZA CA  1 
ATOM   233  C C   . ALA A 1 61  ? 38.04400 43.20300 94.05100  1.000 80.02000  ?  603  ALA AAZA C   1 
ATOM   234  O O   . ALA A 1 61  ? 37.55500 42.58900 94.99600  1.000 79.58000  ?  603  ALA AAZA O   1 
ATOM   235  C CB  . ALA A 1 61  ? 37.00300 44.81800 92.41100  1.000 75.37000  ?  603  ALA AAZA CB  1 
ATOM   236  N N   . GLY A 1 62  ? 39.24300 43.74700 94.09900  1.000 78.37000  ?  604  GLY AAZA N   1 
ATOM   237  C CA  . GLY A 1 62  ? 40.04300 43.63800 95.28900  1.000 75.13000  ?  604  GLY AAZA CA  1 
ATOM   238  C C   . GLY A 1 62  ? 41.41600 44.17400 94.99100  1.000 80.13000  ?  604  GLY AAZA C   1 
ATOM   239  O O   . GLY A 1 62  ? 41.90700 44.02500 93.86700  1.000 83.10000  ?  604  GLY AAZA O   1 
ATOM   240  N N   . THR A 1 63  ? 42.03400 44.81800 95.97600  1.000 77.52000  ?  605  THR AAZA N   1 
ATOM   241  C CA  . THR A 1 63  ? 43.43400 45.18300 95.87100  1.000 75.70000  ?  605  THR AAZA CA  1 
ATOM   242  C C   . THR A 1 63  ? 44.24900 43.94100 95.55800  1.000 78.45000  ?  605  THR AAZA C   1 
ATOM   243  O O   . THR A 1 63  ? 43.76200 42.81800 95.71100  1.000 76.66000  ?  605  THR AAZA O   1 
ATOM   244  C CB  . THR A 1 63  ? 43.90800 45.80900 97.16900  1.000 80.53000  ?  605  THR AAZA CB  1 
ATOM   245  O OG1 . THR A 1 63  ? 44.35000 44.76900 98.04700  1.000 88.09000  ?  605  THR AAZA OG1 1 
ATOM   246  C CG2 . THR A 1 63  ? 42.75900 46.50500 97.83000  1.000 85.05000  ?  605  THR AAZA CG2 1 
ATOM   247  N N   . VAL A 1 64  ? 45.49300 44.11500 95.12500  1.000 81.54000  ?  606  VAL AAZA N   1 
ATOM   248  C CA  . VAL A 1 64  ? 46.29800 42.94100 94.80400  1.000 79.59000  ?  606  VAL AAZA CA  1 
ATOM   249  C C   . VAL A 1 64  ? 46.58300 42.11600 96.06200  1.000 80.49000  ?  606  VAL AAZA C   1 
ATOM   250  O O   . VAL A 1 64  ? 46.52900 40.88000 96.02900  1.000 80.80000  ?  606  VAL AAZA O   1 
ATOM   251  C CB  . VAL A 1 64  ? 47.57800 43.37200 94.06900  1.000 73.02000  ?  606  VAL AAZA CB  1 
ATOM   252  C CG1 . VAL A 1 64  ? 48.28400 44.41500 94.88000  1.000 89.13000  ?  606  VAL AAZA CG1 1 
ATOM   253  C CG2 . VAL A 1 64  ? 48.47600 42.19200 93.80900  1.000 61.90000  ?  606  VAL AAZA CG2 1 
ATOM   254  N N   . ILE A 1 65  ? 46.83500 42.77300 97.20000  1.000 81.34000  ?  607  ILE AAZA N   1 
ATOM   255  C CA  . ILE A 1 65  ? 47.15700 42.03100 98.42300  1.000 84.11000  ?  607  ILE AAZA CA  1 
ATOM   256  C C   . ILE A 1 65  ? 45.96900 41.16600 98.83200  1.000 82.13000  ?  607  ILE AAZA C   1 
ATOM   257  O O   . ILE A 1 65  ? 46.08700 39.94200 98.98000  1.000 83.68000  ?  607  ILE AAZA O   1 
ATOM   258  C CB  . ILE A 1 65  ? 47.56300 42.98300 99.56300  1.000 80.28000  ?  607  ILE AAZA CB  1 
ATOM   259  C CG1 . ILE A 1 65  ? 48.62100 43.96900 99.08900  1.000 91.41000  ?  607  ILE AAZA CG1 1 
ATOM   260  C CG2 . ILE A 1 65  ? 48.28000 42.20300 100.63800 1.000 66.24000  ?  607  ILE AAZA CG2 1 
ATOM   261  C CD1 . ILE A 1 65  ? 48.03500 45.30600 98.60100  1.000 93.58000  ?  607  ILE AAZA CD1 1 
ATOM   262  N N   . LYS A 1 66  ? 44.80500 41.80000 99.00900  1.000 76.31000  ?  608  LYS AAZA N   1 
ATOM   263  C CA  . LYS A 1 66  ? 43.56300 41.07600 99.26000  1.000 76.23000  ?  608  LYS AAZA CA  1 
ATOM   264  C C   . LYS A 1 66  ? 43.36100 39.92700 98.27800  1.000 80.64000  ?  608  LYS AAZA C   1 
ATOM   265  O O   . LYS A 1 66  ? 42.92600 38.83500 98.66000  1.000 82.35000  ?  608  LYS AAZA O   1 
ATOM   266  C CB  . LYS A 1 66  ? 42.38900 42.04800 99.18200  1.000 78.26000  ?  608  LYS AAZA CB  1 
ATOM   267  C CG  . LYS A 1 66  ? 41.92400 42.54700 100.52800 1.000 90.97000  ?  608  LYS AAZA CG  1 
ATOM   268  C CD  . LYS A 1 66  ? 41.56400 41.38300 101.41600 1.000 94.75000  ?  608  LYS AAZA CD  1 
ATOM   269  C CE  . LYS A 1 66  ? 41.50600 41.75400 102.86800 1.000 98.16000  ?  608  LYS AAZA CE  1 
ATOM   270  N NZ  . LYS A 1 66  ? 41.18300 40.52100 103.65300 1.000 100.24000 ?  608  LYS AAZA NZ  1 
ATOM   271  N N   . LEU A 1 67  ? 43.67100 40.15500 97.00100  1.000 83.71000  ?  609  LEU AAZA N   1 
ATOM   272  C CA  . LEU A 1 67  ? 43.44200 39.13400 95.98400  1.000 77.55000  ?  609  LEU AAZA CA  1 
ATOM   273  C C   . LEU A 1 67  ? 44.34300 37.93000 96.19400  1.000 82.21000  ?  609  LEU AAZA C   1 
ATOM   274  O O   . LEU A 1 67  ? 43.92200 36.80000 95.92400  1.000 82.84000  ?  609  LEU AAZA O   1 
ATOM   275  C CB  . LEU A 1 67  ? 43.65300 39.72800 94.60200  1.000 73.82000  ?  609  LEU AAZA CB  1 
ATOM   276  C CG  . LEU A 1 67  ? 42.44500 40.34600 93.90700  1.000 73.60000  ?  609  LEU AAZA CG  1 
ATOM   277  C CD1 . LEU A 1 67  ? 42.81600 40.59100 92.47400  1.000 72.56000  ?  609  LEU AAZA CD1 1 
ATOM   278  C CD2 . LEU A 1 67  ? 41.24500 39.42000 93.98200  1.000 68.95000  ?  609  LEU AAZA CD2 1 
ATOM   279  N N   . ILE A 1 68  ? 45.57400 38.14800 96.67800  1.000 83.55000  ?  610  ILE AAZA N   1 
ATOM   280  C CA  . ILE A 1 68  ? 46.44200 37.02800 97.03900  1.000 82.28000  ?  610  ILE AAZA CA  1 
ATOM   281  C C   . ILE A 1 68  ? 45.89400 36.32400 98.26700  1.000 85.54000  ?  610  ILE AAZA C   1 
ATOM   282  O O   . ILE A 1 68  ? 45.82800 35.09000 98.32000  1.000 85.89000  ?  610  ILE AAZA O   1 
ATOM   283  C CB  . ILE A 1 68  ? 47.88800 37.49400 97.28300  1.000 79.93000  ?  610  ILE AAZA CB  1 
ATOM   284  C CG1 . ILE A 1 68  ? 48.41600 38.28100 96.10000  1.000 81.75000  ?  610  ILE AAZA CG1 1 
ATOM   285  C CG2 . ILE A 1 68  ? 48.80100 36.29200 97.51500  1.000 80.92000  ?  610  ILE AAZA CG2 1 
ATOM   286  C CD1 . ILE A 1 68  ? 49.20400 37.44400 95.12900  1.000 79.00000  ?  610  ILE AAZA CD1 1 
ATOM   287  N N   . GLU A 1 69  ? 45.51800 37.10200 99.28400  1.000 87.30000  ?  611  GLU AAZA N   1 
ATOM   288  C CA  . GLU A 1 69  ? 44.97400 36.51800 100.50400 1.000 90.01000  ?  611  GLU AAZA CA  1 
ATOM   289  C C   . GLU A 1 69  ? 43.85200 35.54500 100.18800 1.000 89.65000  ?  611  GLU AAZA C   1 
ATOM   290  O O   . GLU A 1 69  ? 43.83600 34.41800 100.69200 1.000 93.79000  ?  611  GLU AAZA O   1 
ATOM   291  C CB  . GLU A 1 69  ? 44.47500 37.61200 101.44400 1.000 91.59000  ?  611  GLU AAZA CB  1 
ATOM   292  C CG  . GLU A 1 69  ? 43.79000 37.06800 102.68600 1.000 97.50000  ?  611  GLU AAZA CG  1 
ATOM   293  C CD  . GLU A 1 69  ? 43.03000 38.14200 103.44300 1.000 106.13000 ?  611  GLU AAZA CD  1 
ATOM   294  O OE1 . GLU A 1 69  ? 43.45800 39.32600 103.40400 1.000 104.68000 ?  611  GLU AAZA OE1 1 
ATOM   295  O OE2 . GLU A 1 69  ? 41.97800 37.80000 104.04100 1.000 108.44000 ?  611  GLU AAZA OE2 1 
ATOM   296  N N   . ARG A 1 70  ? 42.90700 35.95700 99.34200  1.000 82.85000  ?  612  ARG AAZA N   1 
ATOM   297  C CA  . ARG A 1 70  ? 41.82300 35.05200 99.00000  1.000 83.09000  ?  612  ARG AAZA CA  1 
ATOM   298  C C   . ARG A 1 70  ? 42.30000 33.89400 98.13800  1.000 82.58000  ?  612  ARG AAZA C   1 
ATOM   299  O O   . ARG A 1 70  ? 41.70600 32.81600 98.18400  1.000 83.72000  ?  612  ARG AAZA O   1 
ATOM   300  C CB  . ARG A 1 70  ? 40.70600 35.82600 98.31500  1.000 83.89000  ?  612  ARG AAZA CB  1 
ATOM   301  C CG  . ARG A 1 70  ? 39.90700 36.67100 99.27700  1.000 90.73000  ?  612  ARG AAZA CG  1 
ATOM   302  C CD  . ARG A 1 70  ? 38.76200 35.87600 99.91000  1.000 97.78000  ?  612  ARG AAZA CD  1 
ATOM   303  N NE  . ARG A 1 70  ? 38.20600 36.56400 101.07200 1.000 99.18000  ?  612  ARG AAZA NE  1 
ATOM   304  C CZ  . ARG A 1 70  ? 37.10000 36.19400 101.70400 1.000 101.14000 ?  612  ARG AAZA CZ  1 
ATOM   305  N NH1 . ARG A 1 70  ? 36.37100 35.17200 101.28100 1.000 105.17000 ?  612  ARG AAZA NH1 1 
ATOM   306  N NH2 . ARG A 1 70  ? 36.71400 36.86500 102.78600 1.000 103.77000 ?  612  ARG AAZA NH2 1 
ATOM   307  N N   . LEU A 1 71  ? 43.38300 34.07300 97.38600  1.000 83.17000  ?  613  LEU AAZA N   1 
ATOM   308  C CA  . LEU A 1 71  ? 43.97500 32.96600 96.64200  1.000 83.79000  ?  613  LEU AAZA CA  1 
ATOM   309  C C   . LEU A 1 71  ? 44.59200 31.91100 97.56800  1.000 80.19000  ?  613  LEU AAZA C   1 
ATOM   310  O O   . LEU A 1 71  ? 44.81200 30.76700 97.15300  1.000 75.74000  ?  613  LEU AAZA O   1 
ATOM   311  C CB  . LEU A 1 71  ? 45.01200 33.54000 95.65500  1.000 82.12000  ?  613  LEU AAZA CB  1 
ATOM   312  C CG  . LEU A 1 71  ? 45.71600 32.65700 94.62200  1.000 73.74000  ?  613  LEU AAZA CG  1 
ATOM   313  C CD1 . LEU A 1 71  ? 44.69500 32.14700 93.65500  1.000 67.00000  ?  613  LEU AAZA CD1 1 
ATOM   314  C CD2 . LEU A 1 71  ? 46.85700 33.42100 93.93900  1.000 59.64000  ?  613  LEU AAZA CD2 1 
ATOM   315  N N   . THR A 1 72  ? 44.86100 32.26900 98.81600  1.000 83.42000  ?  614  THR AAZA N   1 
ATOM   316  C CA  . THR A 1 72  ? 45.44900 31.37300 99.78800  1.000 86.49000  ?  614  THR AAZA CA  1 
ATOM   317  C C   . THR A 1 72  ? 44.69800 31.54300 101.11100 1.000 92.84000  ?  614  THR AAZA C   1 
ATOM   318  O O   . THR A 1 72  ? 45.22600 32.01700 102.11500 1.000 95.93000  ?  614  THR AAZA O   1 
ATOM   319  C CB  . THR A 1 72  ? 46.93400 31.67900 99.93800  1.000 87.29000  ?  614  THR AAZA CB  1 
ATOM   320  O OG1 . THR A 1 72  ? 47.09100 33.08300 100.17600 1.000 82.96000  ?  614  THR AAZA OG1 1 
ATOM   321  C CG2 . THR A 1 72  ? 47.70200 31.28400 98.67400  1.000 81.50000  ?  614  THR AAZA CG2 1 
ATOM   322  N N   . TYR A 1 73  ? 43.42000 31.17800 101.11700 1.000 89.79000  ?  615  TYR AAZA N   1 
ATOM   323  C CA  . TYR A 1 73  ? 42.57100 31.42400 102.27400 1.000 94.97000  ?  615  TYR AAZA CA  1 
ATOM   324  C C   . TYR A 1 73  ? 42.58800 30.23500 103.22600 1.000 102.02000 ?  615  TYR AAZA C   1 
ATOM   325  O O   . TYR A 1 73  ? 42.50300 29.08200 102.79600 1.000 104.60000 ?  615  TYR AAZA O   1 
ATOM   326  C CB  . TYR A 1 73  ? 41.14600 31.72900 101.81400 1.000 95.19000  ?  615  TYR AAZA CB  1 
ATOM   327  C CG  . TYR A 1 73  ? 40.37600 32.67600 102.71400 1.000 99.74000  ?  615  TYR AAZA CG  1 
ATOM   328  C CD1 . TYR A 1 73  ? 41.00600 33.74000 103.36000 1.000 99.25000  ?  615  TYR AAZA CD1 1 
ATOM   329  C CD2 . TYR A 1 73  ? 39.00500 32.52900 102.87900 1.000 99.72000  ?  615  TYR AAZA CD2 1 
ATOM   330  C CE1 . TYR A 1 73  ? 40.29400 34.60300 104.17200 1.000 100.67000 ?  615  TYR AAZA CE1 1 
ATOM   331  C CE2 . TYR A 1 73  ? 38.28400 33.38600 103.68100 1.000 101.04000 ?  615  TYR AAZA CE2 1 
ATOM   332  C CZ  . TYR A 1 73  ? 38.93000 34.41900 104.32600 1.000 104.02000 ?  615  TYR AAZA CZ  1 
ATOM   333  O OH  . TYR A 1 73  ? 38.19700 35.26700 105.12600 1.000 107.61000 ?  615  TYR AAZA OH  1 
ATOM   334  N N   . HIS A 1 74  ? 42.69100 30.52200 104.52800 1.000 100.71000 ?  616  HIS AAZA N   1 
ATOM   335  C CA  . HIS A 1 74  ? 42.71700 29.45300 105.52700 1.000 104.59000 ?  616  HIS AAZA CA  1 
ATOM   336  C C   . HIS A 1 74  ? 41.44200 28.60800 105.48700 1.000 104.83000 ?  616  HIS AAZA C   1 
ATOM   337  O O   . HIS A 1 74  ? 41.49700 27.37300 105.51900 1.000 105.41000 ?  616  HIS AAZA O   1 
ATOM   338  C CB  . HIS A 1 74  ? 42.89400 30.04900 106.91800 1.000 107.26000 ?  616  HIS AAZA CB  1 
ATOM   339  C CG  . HIS A 1 74  ? 41.82700 31.03800 107.27100 1.000 114.62000 ?  616  HIS AAZA CG  1 
ATOM   340  N ND1 . HIS A 1 74  ? 41.86900 32.35900 106.87300 1.000 115.93000 ?  616  HIS AAZA ND1 1 
ATOM   341  C CD2 . HIS A 1 74  ? 40.66900 30.88800 107.95600 1.000 112.50000 ?  616  HIS AAZA CD2 1 
ATOM   342  C CE1 . HIS A 1 74  ? 40.78900 32.98300 107.31100 1.000 113.88000 ?  616  HIS AAZA CE1 1 
ATOM   343  N NE2 . HIS A 1 74  ? 40.04200 32.11100 107.96600 1.000 113.04000 ?  616  HIS AAZA NE2 1 
ATOM   344  N N   . MET A 1 75  ? 40.28000 29.26200 105.40800 1.000 102.80000 ?  617  MET AAZA N   1 
ATOM   345  C CA  . MET A 1 75  ? 39.00400 28.58300 105.62300 1.000 105.13000 ?  617  MET AAZA CA  1 
ATOM   346  C C   . MET A 1 75  ? 38.68100 27.57900 104.51600 1.000 100.79000 ?  617  MET AAZA C   1 
ATOM   347  O O   . MET A 1 75  ? 38.13600 26.50100 104.78500 1.000 102.78000 ?  617  MET AAZA O   1 
ATOM   348  C CB  . MET A 1 75  ? 37.88400 29.62000 105.75300 1.000 108.48000 ?  617  MET AAZA CB  1 
ATOM   349  C CG  . MET A 1 75  ? 37.65800 30.14300 107.17400 1.000 108.79000 ?  617  MET AAZA CG  1 
ATOM   350  S SD  . MET A 1 75  ? 36.63100 31.63100 107.23600 1.000 120.58000 ?  617  MET AAZA SD  1 
ATOM   351  C CE  . MET A 1 75  ? 36.63300 32.00100 108.99200 1.000 119.87000 ?  617  MET AAZA CE  1 
ATOM   352  N N   . TYR A 1 76  ? 38.98900 27.90900 103.26700 1.000 104.40000 ?  618  TYR AAZA N   1 
ATOM   353  C CA  . TYR A 1 76  ? 38.63800 27.02500 102.15900 1.000 110.16000 ?  618  TYR AAZA CA  1 
ATOM   354  C C   . TYR A 1 76  ? 39.58100 27.26200 100.99400 1.000 101.80000 ?  618  TYR AAZA C   1 
ATOM   355  O O   . TYR A 1 76  ? 40.23300 28.30500 100.89000 1.000 100.28000 ?  618  TYR AAZA O   1 
ATOM   356  C CB  . TYR A 1 76  ? 37.18700 27.22300 101.70200 1.000 104.89000 ?  618  TYR AAZA CB  1 
ATOM   357  C CG  . TYR A 1 76  ? 36.85800 28.66700 101.44800 1.000 101.65000 ?  618  TYR AAZA CG  1 
ATOM   358  C CD1 . TYR A 1 76  ? 36.58100 29.51700 102.50200 1.000 101.76000 ?  618  TYR AAZA CD1 1 
ATOM   359  C CD2 . TYR A 1 76  ? 36.80300 29.17600 100.17000 1.000 97.72000  ?  618  TYR AAZA CD2 1 
ATOM   360  C CE1 . TYR A 1 76  ? 36.29000 30.82800 102.29400 1.000 101.40000 ?  618  TYR AAZA CE1 1 
ATOM   361  C CE2 . TYR A 1 76  ? 36.50100 30.49200 99.95600  1.000 99.73000  ?  618  TYR AAZA CE2 1 
ATOM   362  C CZ  . TYR A 1 76  ? 36.24400 31.31300 101.02500 1.000 98.93000  ?  618  TYR AAZA CZ  1 
ATOM   363  O OH  . TYR A 1 76  ? 35.94400 32.63800 100.84500 1.000 103.98000 ?  618  TYR AAZA OH  1 
ATOM   364  N N   . ALA A 1 77  ? 39.65400 26.26500 100.13000 1.000 97.67000  ?  619  ALA AAZA N   1 
ATOM   365  C CA  . ALA A 1 77  ? 40.35700 26.39900 98.86900  1.000 102.50000 ?  619  ALA AAZA CA  1 
ATOM   366  C C   . ALA A 1 77  ? 39.35000 26.75800 97.79000  1.000 99.04000  ?  619  ALA AAZA C   1 
ATOM   367  O O   . ALA A 1 77  ? 38.19300 26.33300 97.83300  1.000 104.50000 ?  619  ALA AAZA O   1 
ATOM   368  C CB  . ALA A 1 77  ? 41.09400 25.10900 98.49800  1.000 104.87000 ?  619  ALA AAZA CB  1 
ATOM   369  N N   . ASP A 1 78  ? 39.79000 27.56500 96.83300  1.000 93.56000  ?  620  ASP AAZA N   1 
ATOM   370  C CA  . ASP A 1 78  ? 38.92200 27.99700 95.73800  1.000 93.26000  ?  620  ASP AAZA CA  1 
ATOM   371  C C   . ASP A 1 78  ? 39.56900 27.60400 94.41000  1.000 92.64000  ?  620  ASP AAZA C   1 
ATOM   372  O O   . ASP A 1 78  ? 40.45600 28.31700 93.90900  1.000 92.39000  ?  620  ASP AAZA O   1 
ATOM   373  C CB  . ASP A 1 78  ? 38.68100 29.50400 95.82100  1.000 87.33000  ?  620  ASP AAZA CB  1 
ATOM   374  C CG  . ASP A 1 78  ? 37.59400 29.96200 94.89000  1.000 95.96000  ?  620  ASP AAZA CG  1 
ATOM   375  O OD1 . ASP A 1 78  ? 37.17300 29.14500 94.03300  1.000 93.09000  ?  620  ASP AAZA OD1 1 
ATOM   376  O OD2 . ASP A 1 78  ? 37.16300 31.13500 95.00800  1.000 102.49000 ?  620  ASP AAZA OD2 1 
ATOM   377  N N   . PRO A 1 79  ? 39.19100 26.48000 93.80200  1.000 89.06000  ?  621  PRO AAZA N   1 
ATOM   378  C CA  . PRO A 1 79  ? 39.93600 26.03500 92.62000  1.000 89.03000  ?  621  PRO AAZA CA  1 
ATOM   379  C C   . PRO A 1 79  ? 39.69000 26.91100 91.41200  1.000 93.38000  ?  621  PRO AAZA C   1 
ATOM   380  O O   . PRO A 1 79  ? 40.62000 27.12200 90.62700  1.000 92.24000  ?  621  PRO AAZA O   1 
ATOM   381  C CB  . PRO A 1 79  ? 39.42900 24.60300 92.39000  1.000 91.42000  ?  621  PRO AAZA CB  1 
ATOM   382  C CG  . PRO A 1 79  ? 38.61000 24.27200 93.58900  1.000 95.15000  ?  621  PRO AAZA CG  1 
ATOM   383  C CD  . PRO A 1 79  ? 38.09600 25.55900 94.12500  1.000 93.01000  ?  621  PRO AAZA CD  1 
ATOM   384  N N   . ASN A 1 80  ? 38.46500 27.42500 91.23500  1.000 96.11000  ?  622  ASN AAZA N   1 
ATOM   385  C CA  . ASN A 1 80  ? 38.16600 28.25300 90.06800  1.000 91.14000  ?  622  ASN AAZA CA  1 
ATOM   386  C C   . ASN A 1 80  ? 38.83800 29.60800 90.16600  1.000 86.24000  ?  622  ASN AAZA C   1 
ATOM   387  O O   . ASN A 1 80  ? 39.24200 30.17600 89.14700  1.000 87.05000  ?  622  ASN AAZA O   1 
ATOM   388  C CB  . ASN A 1 80  ? 36.66200 28.43500 89.91700  1.000 95.05000  ?  622  ASN AAZA CB  1 
ATOM   389  C CG  . ASN A 1 80  ? 35.96000 27.14400 89.63800  1.000 100.19000 ?  622  ASN AAZA CG  1 
ATOM   390  O OD1 . ASN A 1 80  ? 36.19500 26.50800 88.60900  1.000 100.97000 ?  622  ASN AAZA OD1 1 
ATOM   391  N ND2 . ASN A 1 80  ? 35.11400 26.72100 90.57000  1.000 106.70000 ?  622  ASN AAZA ND2 1 
ATOM   392  N N   . PHE A 1 81  ? 38.93300 30.15600 91.37600  1.000 83.40000  ?  623  PHE AAZA N   1 
ATOM   393  C CA  . PHE A 1 81  ? 39.72800 31.35700 91.58000  1.000 78.76000  ?  623  PHE AAZA CA  1 
ATOM   394  C C   . PHE A 1 81  ? 41.18100 31.09400 91.22000  1.000 81.35000  ?  623  PHE AAZA C   1 
ATOM   395  O O   . PHE A 1 81  ? 41.78300 31.84400 90.44500  1.000 80.37000  ?  623  PHE AAZA O   1 
ATOM   396  C CB  . PHE A 1 81  ? 39.61000 31.82300 93.02600  1.000 74.93000  ?  623  PHE AAZA CB  1 
ATOM   397  C CG  . PHE A 1 81  ? 40.25200 33.13900 93.29800  1.000 74.14000  ?  623  PHE AAZA CG  1 
ATOM   398  C CD1 . PHE A 1 81  ? 39.66600 34.31100 92.85800  1.000 76.54000  ?  623  PHE AAZA CD1 1 
ATOM   399  C CD2 . PHE A 1 81  ? 41.44000 33.21500 93.99800  1.000 76.62000  ?  623  PHE AAZA CD2 1 
ATOM   400  C CE1 . PHE A 1 81  ? 40.24700 35.53900 93.11500  1.000 71.10000  ?  623  PHE AAZA CE1 1 
ATOM   401  C CE2 . PHE A 1 81  ? 42.02800 34.44300 94.25700  1.000 77.30000  ?  623  PHE AAZA CE2 1 
ATOM   402  C CZ  . PHE A 1 81  ? 41.42500 35.60600 93.81200  1.000 75.93000  ?  623  PHE AAZA CZ  1 
ATOM   403  N N   . VAL A 1 82  ? 41.76400 30.01900 91.75600  1.000 82.59000  ?  624  VAL AAZA N   1 
ATOM   404  C CA  . VAL A 1 82  ? 43.15800 29.73500 91.44300  1.000 76.54000  ?  624  VAL AAZA CA  1 
ATOM   405  C C   . VAL A 1 82  ? 43.34000 29.59600 89.94400  1.000 71.64000  ?  624  VAL AAZA C   1 
ATOM   406  O O   . VAL A 1 82  ? 44.25100 30.19200 89.36900  1.000 74.46000  ?  624  VAL AAZA O   1 
ATOM   407  C CB  . VAL A 1 82  ? 43.66100 28.49500 92.20000  1.000 81.56000  ?  624  VAL AAZA CB  1 
ATOM   408  C CG1 . VAL A 1 82  ? 45.01000 28.04400 91.63700  1.000 79.37000  ?  624  VAL AAZA CG1 1 
ATOM   409  C CG2 . VAL A 1 82  ? 43.81800 28.82000 93.66900  1.000 77.22000  ?  624  VAL AAZA CG2 1 
ATOM   410  N N   . ARG A 1 83  ? 42.45100 28.84200 89.30800  1.000 77.21000  ?  625  ARG AAZA N   1 
ATOM   411  C CA  . ARG A 1 83  ? 42.54300 28.61800 87.84400  1.000 80.98000  ?  625  ARG AAZA CA  1 
ATOM   412  C C   . ARG A 1 83  ? 42.44400 29.95800 87.12500  1.000 76.61000  ?  625  ARG AAZA C   1 
ATOM   413  O O   . ARG A 1 83  ? 43.30400 30.24400 86.28300  1.000 77.92000  ?  625  ARG AAZA O   1 
ATOM   414  C CB  . ARG A 1 83  ? 41.39000 27.72500 87.38800  1.000 83.56000  ?  625  ARG AAZA CB  1 
ATOM   415  C CG  . ARG A 1 83  ? 41.61200 27.03000 86.05400  1.000 92.10000  ?  625  ARG AAZA CG  1 
ATOM   416  C CD  . ARG A 1 83  ? 40.38100 26.22900 85.67500  1.000 97.84000  ?  625  ARG AAZA CD  1 
ATOM   417  N NE  . ARG A 1 83  ? 39.72800 25.62400 86.82900  1.000 107.60000 ?  625  ARG AAZA NE  1 
ATOM   418  C CZ  . ARG A 1 83  ? 40.29000 24.73900 87.64400  1.000 114.79000 ?  625  ARG AAZA CZ  1 
ATOM   419  N NH1 . ARG A 1 83  ? 41.42800 24.15700 87.31000  1.000 106.13000 ?  625  ARG AAZA NH1 1 
ATOM   420  N NH2 . ARG A 1 83  ? 39.70800 24.43500 88.79100  1.000 107.60000 ?  625  ARG AAZA NH2 1 
ATOM   421  N N   . THR A 1 84  ? 41.41800 30.73800 87.44700  1.000 74.34000  ?  626  THR AAZA N   1 
ATOM   422  C CA  . THR A 1 84  ? 41.21900 32.01600 86.77000  1.000 73.22000  ?  626  THR AAZA CA  1 
ATOM   423  C C   . THR A 1 84  ? 42.39900 32.96100 87.00600  1.000 72.22000  ?  626  THR AAZA C   1 
ATOM   424  O O   . THR A 1 84  ? 42.90100 33.58700 86.06800  1.000 70.64000  ?  626  THR AAZA O   1 
ATOM   425  C CB  . THR A 1 84  ? 39.90900 32.64700 87.24500  1.000 73.76000  ?  626  THR AAZA CB  1 
ATOM   426  O OG1 . THR A 1 84  ? 38.80700 31.86900 86.77100  1.000 75.25000  ?  626  THR AAZA OG1 1 
ATOM   427  C CG2 . THR A 1 84  ? 39.76100 34.05300 86.73900  1.000 73.27000  ?  626  THR AAZA CG2 1 
ATOM   428  N N   . PHE A 1 85  ? 42.86600 33.05800 88.25000  1.000 75.04000  ?  627  PHE AAZA N   1 
ATOM   429  C CA  . PHE A 1 85  ? 43.93600 33.98900 88.60800  1.000 72.19000  ?  627  PHE AAZA CA  1 
ATOM   430  C C   . PHE A 1 85  ? 45.23500 33.68600 87.85000  1.000 72.43000  ?  627  PHE AAZA C   1 
ATOM   431  O O   . PHE A 1 85  ? 45.80300 34.56400 87.18700  1.000 70.62000  ?  627  PHE AAZA O   1 
ATOM   432  C CB  . PHE A 1 85  ? 44.15600 33.94000 90.12600  1.000 67.82000  ?  627  PHE AAZA CB  1 
ATOM   433  C CG  . PHE A 1 85  ? 45.16700 34.92000 90.62900  1.000 65.05000  ?  627  PHE AAZA CG  1 
ATOM   434  C CD1 . PHE A 1 85  ? 46.52300 34.67300 90.49700  1.000 59.53000  ?  627  PHE AAZA CD1 1 
ATOM   435  C CD2 . PHE A 1 85  ? 44.76000 36.08700 91.24200  1.000 65.06000  ?  627  PHE AAZA CD2 1 
ATOM   436  C CE1 . PHE A 1 85  ? 47.43900 35.57400 90.94600  1.000 56.53000  ?  627  PHE AAZA CE1 1 
ATOM   437  C CE2 . PHE A 1 85  ? 45.67900 36.98600 91.70300  1.000 61.06000  ?  627  PHE AAZA CE2 1 
ATOM   438  C CZ  . PHE A 1 85  ? 47.01700 36.72100 91.55900  1.000 59.35000  ?  627  PHE AAZA CZ  1 
ATOM   439  N N   . LEU A 1 86  ? 45.74700 32.45500 87.96200  1.000 70.22000  ?  628  LEU AAZA N   1 
ATOM   440  C CA  . LEU A 1 86  ? 46.97800 32.12200 87.25400  1.000 69.40000  ?  628  LEU AAZA CA  1 
ATOM   441  C C   . LEU A 1 86  ? 46.85400 32.29400 85.73000  1.000 72.03000  ?  628  LEU AAZA C   1 
ATOM   442  O O   . LEU A 1 86  ? 47.87800 32.47900 85.05700  1.000 70.44000  ?  628  LEU AAZA O   1 
ATOM   443  C CB  . LEU A 1 86  ? 47.41200 30.69600 87.60400  1.000 65.32000  ?  628  LEU AAZA CB  1 
ATOM   444  C CG  . LEU A 1 86  ? 47.99000 30.44600 88.98900  1.000 61.17000  ?  628  LEU AAZA CG  1 
ATOM   445  C CD1 . LEU A 1 86  ? 48.31500 28.98900 89.12900  1.000 66.04000  ?  628  LEU AAZA CD1 1 
ATOM   446  C CD2 . LEU A 1 86  ? 49.22500 31.28100 89.24000  1.000 62.30000  ?  628  LEU AAZA CD2 1 
ATOM   447  N N   . THR A 1 87  ? 45.63000 32.25800 85.17000  1.000 68.67000  ?  629  THR AAZA N   1 
ATOM   448  C CA  . THR A 1 87  ? 45.43600 32.52900 83.74300  1.000 68.72000  ?  629  THR AAZA CA  1 
ATOM   449  C C   . THR A 1 87  ? 45.45700 34.02700 83.41500  1.000 69.16000  ?  629  THR AAZA C   1 
ATOM   450  O O   . THR A 1 87  ? 45.78700 34.40000 82.28200  1.000 71.65000  ?  629  THR AAZA O   1 
ATOM   451  C CB  . THR A 1 87  ? 44.11300 31.90000 83.23900  1.000 67.91000  ?  629  THR AAZA CB  1 
ATOM   452  O OG1 . THR A 1 87  ? 44.20600 30.47400 83.24400  1.000 72.35000  ?  629  THR AAZA OG1 1 
ATOM   453  C CG2 . THR A 1 87  ? 43.75800 32.33400 81.81400  1.000 64.06000  ?  629  THR AAZA CG2 1 
ATOM   454  N N   . THR A 1 88  ? 45.11400 34.91200 84.35300  1.000 63.09000  ?  630  THR AAZA N   1 
ATOM   455  C CA  . THR A 1 88  ? 44.86400 36.28500 83.93900  1.000 65.55000  ?  630  THR AAZA CA  1 
ATOM   456  C C   . THR A 1 88  ? 45.59900 37.35600 84.74700  1.000 65.90000  ?  630  THR AAZA C   1 
ATOM   457  O O   . THR A 1 88  ? 45.34200 38.54400 84.53900  1.000 67.31000  ?  630  THR AAZA O   1 
ATOM   458  C CB  . THR A 1 88  ? 43.34600 36.56800 83.93700  1.000 68.01000  ?  630  THR AAZA CB  1 
ATOM   459  O OG1 . THR A 1 88  ? 42.83800 36.71800 85.26900  1.000 68.20000  ?  630  THR AAZA OG1 1 
ATOM   460  C CG2 . THR A 1 88  ? 42.58800 35.44000 83.26500  1.000 66.35000  ?  630  THR AAZA CG2 1 
ATOM   461  N N   . TYR A 1 89  ? 46.52500 36.99600 85.63100  1.000 65.64000  ?  631  TYR AAZA N   1 
ATOM   462  C CA  . TYR A 1 89  ? 47.07200 38.00900 86.53700  1.000 66.92000  ?  631  TYR AAZA CA  1 
ATOM   463  C C   . TYR A 1 89  ? 48.05900 38.95800 85.86100  1.000 69.50000  ?  631  TYR AAZA C   1 
ATOM   464  O O   . TYR A 1 89  ? 48.28900 40.06400 86.37200  1.000 67.99000  ?  631  TYR AAZA O   1 
ATOM   465  C CB  . TYR A 1 89  ? 47.74700 37.34400 87.74100  1.000 60.31000  ?  631  TYR AAZA CB  1 
ATOM   466  C CG  . TYR A 1 89  ? 49.07000 36.67900 87.42300  1.000 58.81000  ?  631  TYR AAZA CG  1 
ATOM   467  C CD1 . TYR A 1 89  ? 50.26500 37.38600 87.48000  1.000 56.68000  ?  631  TYR AAZA CD1 1 
ATOM   468  C CD2 . TYR A 1 89  ? 49.11200 35.34800 87.03900  1.000 57.29000  ?  631  TYR AAZA CD2 1 
ATOM   469  C CE1 . TYR A 1 89  ? 51.45400 36.77900 87.18400  1.000 58.18000  ?  631  TYR AAZA CE1 1 
ATOM   470  C CE2 . TYR A 1 89  ? 50.29000 34.73800 86.74200  1.000 56.97000  ?  631  TYR AAZA CE2 1 
ATOM   471  C CZ  . TYR A 1 89  ? 51.46700 35.44400 86.82500  1.000 59.25000  ?  631  TYR AAZA CZ  1 
ATOM   472  O OH  . TYR A 1 89  ? 52.65500 34.80000 86.52700  1.000 59.36000  ?  631  TYR AAZA OH  1 
ATOM   473  N N   . ARG A 1 90  ? 48.66300 38.55000 84.73700  1.000 69.87000  ?  632  ARG AAZA N   1 
ATOM   474  C CA  . ARG A 1 90  ? 49.84300 39.26000 84.25100  1.000 68.76000  ?  632  ARG AAZA CA  1 
ATOM   475  C C   . ARG A 1 90  ? 49.52400 40.67200 83.78900  1.000 72.83000  ?  632  ARG AAZA C   1 
ATOM   476  O O   . ARG A 1 90  ? 50.44800 41.48600 83.63400  1.000 73.57000  ?  632  ARG AAZA O   1 
ATOM   477  C CB  . ARG A 1 90  ? 50.50300 38.44900 83.15400  1.000 58.31000  ?  632  ARG AAZA CB  1 
ATOM   478  C CG  . ARG A 1 90  ? 51.06800 37.18100 83.65900  1.000 56.04000  ?  632  ARG AAZA CG  1 
ATOM   479  C CD  . ARG A 1 90  ? 51.42800 36.24300 82.56600  1.000 62.95000  ?  632  ARG AAZA CD  1 
ATOM   480  N NE  . ARG A 1 90  ? 51.45900 34.87200 83.03800  1.000 62.94000  ?  632  ARG AAZA NE  1 
ATOM   481  C CZ  . ARG A 1 90  ? 50.37400 34.13400 83.18200  1.000 67.05000  ?  632  ARG AAZA CZ  1 
ATOM   482  N NH1 . ARG A 1 90  ? 49.17500 34.62700 82.91400  1.000 67.71000  ?  632  ARG AAZA NH1 1 
ATOM   483  N NH2 . ARG A 1 90  ? 50.49200 32.88400 83.62800  1.000 64.02000  ?  632  ARG AAZA NH2 1 
ATOM   484  N N   . SER A 1 91  ? 48.24200 40.97700 83.63100  1.000 67.97000  ?  633  SER AAZA N   1 
ATOM   485  C CA  . SER A 1 91  ? 47.75300 42.27800 83.24200  1.000 66.98000  ?  633  SER AAZA CA  1 
ATOM   486  C C   . SER A 1 91  ? 47.61600 43.22900 84.40100  1.000 71.39000  ?  633  SER AAZA C   1 
ATOM   487  O O   . SER A 1 91  ? 47.29700 44.39500 84.16400  1.000 79.27000  ?  633  SER AAZA O   1 
ATOM   488  C CB  . SER A 1 91  ? 46.39100 42.14300 82.57300  1.000 77.44000  ?  633  SER AAZA CB  1 
ATOM   489  O OG  . SER A 1 91  ? 45.52400 41.38500 83.38400  1.000 75.85000  ?  633  SER AAZA OG  1 
ATOM   490  N N   . PHE A 1 92  ? 47.78900 42.75600 85.65000  1.000 75.69000  ?  634  PHE AAZA N   1 
ATOM   491  C CA  . PHE A 1 92  ? 47.72600 43.64400 86.80900  1.000 73.42000  ?  634  PHE AAZA CA  1 
ATOM   492  C C   . PHE A 1 92  ? 48.83100 43.41200 87.82400  1.000 71.06000  ?  634  PHE AAZA C   1 
ATOM   493  O O   . PHE A 1 92  ? 48.87700 44.13800 88.82300  1.000 71.14000  ?  634  PHE AAZA O   1 
ATOM   494  C CB  . PHE A 1 92  ? 46.35600 43.55300 87.51400  1.000 74.50000  ?  634  PHE AAZA CB  1 
ATOM   495  C CG  . PHE A 1 92  ? 46.04600 42.20500 88.12700  1.000 75.52000  ?  634  PHE AAZA CG  1 
ATOM   496  C CD1 . PHE A 1 92  ? 46.68200 41.78300 89.29300  1.000 73.60000  ?  634  PHE AAZA CD1 1 
ATOM   497  C CD2 . PHE A 1 92  ? 45.08700 41.37700 87.55900  1.000 73.70000  ?  634  PHE AAZA CD2 1 
ATOM   498  C CE1 . PHE A 1 92  ? 46.39300 40.55800 89.85400  1.000 69.99000  ?  634  PHE AAZA CE1 1 
ATOM   499  C CE2 . PHE A 1 92  ? 44.79400 40.14800 88.12300  1.000 72.59000  ?  634  PHE AAZA CE2 1 
ATOM   500  C CZ  . PHE A 1 92  ? 45.45000 39.73700 89.27600  1.000 67.95000  ?  634  PHE AAZA CZ  1 
ATOM   501  N N   . CYS A 1 93  ? 49.72000 42.44500 87.59300  1.000 72.69000  ?  635  CYS AAZA N   1 
ATOM   502  C CA  . CYS A 1 93  ? 50.78200 42.09000 88.53400  1.000 78.74000  ?  635  CYS AAZA CA  1 
ATOM   503  C C   . CYS A 1 93  ? 51.80400 41.24600 87.78900  1.000 74.82000  ?  635  CYS AAZA C   1 
ATOM   504  O O   . CYS A 1 93  ? 51.45700 40.18000 87.26200  1.000 68.01000  ?  635  CYS AAZA O   1 
ATOM   505  C CB  . CYS A 1 93  ? 50.20500 41.32500 89.74600  1.000 76.97000  ?  635  CYS AAZA CB  1 
ATOM   506  S SG  . CYS A 1 93  ? 51.42200 40.55800 90.84100  1.000 74.73000  ?  635  CYS AAZA SG  1 
ATOM   507  N N   . LYS A 1 94  ? 53.05400 41.71300 87.75100  1.000 78.34000  ?  636  LYS AAZA N   1 
ATOM   508  C CA  . LYS A 1 94  ? 54.08400 41.04300 86.96400  1.000 82.43000  ?  636  LYS AAZA CA  1 
ATOM   509  C C   . LYS A 1 94  ? 54.50700 39.73600 87.64300  1.000 79.09000  ?  636  LYS AAZA C   1 
ATOM   510  O O   . LYS A 1 94  ? 54.42400 39.61500 88.86800  1.000 80.29000  ?  636  LYS AAZA O   1 
ATOM   511  C CB  . LYS A 1 94  ? 55.28900 41.97300 86.76200  1.000 85.09000  ?  636  LYS AAZA CB  1 
ATOM   512  C CG  . LYS A 1 94  ? 54.91300 43.47200 86.66900  1.000 91.57000  ?  636  LYS AAZA CG  1 
ATOM   513  C CD  . LYS A 1 94  ? 53.95200 43.76800 85.47600  1.000 98.91000  ?  636  LYS AAZA CD  1 
ATOM   514  C CE  . LYS A 1 94  ? 52.94100 44.91300 85.78500  1.000 97.13000  ?  636  LYS AAZA CE  1 
ATOM   515  N NZ  . LYS A 1 94  ? 51.82700 45.00900 84.76000  1.000 81.99000  ?  636  LYS AAZA NZ  1 
ATOM   516  N N   . PRO A 1 95  ? 54.94500 38.73300 86.86900  1.000 73.16000  ?  637  PRO AAZA N   1 
ATOM   517  C CA  . PRO A 1 95  ? 55.12700 37.38500 87.44900  1.000 76.39000  ?  637  PRO AAZA CA  1 
ATOM   518  C C   . PRO A 1 95  ? 56.11400 37.33100 88.59900  1.000 75.29000  ?  637  PRO AAZA C   1 
ATOM   519  O O   . PRO A 1 95  ? 56.00900 36.44900 89.45700  1.000 73.51000  ?  637  PRO AAZA O   1 
ATOM   520  C CB  . PRO A 1 95  ? 55.61800 36.55000 86.25800  1.000 64.12000  ?  637  PRO AAZA CB  1 
ATOM   521  C CG  . PRO A 1 95  ? 55.06300 37.23700 85.11600  1.000 70.52000  ?  637  PRO AAZA CG  1 
ATOM   522  C CD  . PRO A 1 95  ? 55.08200 38.70700 85.41500  1.000 69.07000  ?  637  PRO AAZA CD  1 
ATOM   523  N N   . GLN A 1 96  ? 57.07500 38.24300 88.64400  1.000 75.29000  ?  638  GLN AAZA N   1 
ATOM   524  C CA  . GLN A 1 96  ? 58.02200 38.20700 89.74000  1.000 74.35000  ?  638  GLN AAZA CA  1 
ATOM   525  C C   . GLN A 1 96  ? 57.42800 38.81900 91.00900  1.000 80.99000  ?  638  GLN AAZA C   1 
ATOM   526  O O   . GLN A 1 96  ? 57.70400 38.34400 92.11800  1.000 77.67000  ?  638  GLN AAZA O   1 
ATOM   527  C CB  . GLN A 1 96  ? 59.30700 38.88600 89.29800  1.000 65.97000  ?  638  GLN AAZA CB  1 
ATOM   528  C CG  . GLN A 1 96  ? 60.46600 38.38500 90.06200  1.000 83.25000  ?  638  GLN AAZA CG  1 
ATOM   529  C CD  . GLN A 1 96  ? 61.63700 38.03700 89.19600  1.000 90.07000  ?  638  GLN AAZA CD  1 
ATOM   530  O OE1 . GLN A 1 96  ? 61.56200 37.15500 88.33200  1.000 79.53000  ?  638  GLN AAZA OE1 1 
ATOM   531  N NE2 . GLN A 1 96  ? 62.72200 38.78000 89.37400  1.000 100.21000 ?  638  GLN AAZA NE2 1 
ATOM   532  N N   . GLU A 1 97  ? 56.59300 39.85200 90.85100  1.000 83.55000  ?  639  GLU AAZA N   1 
ATOM   533  C CA  . GLU A 1 97  ? 55.75400 40.35100 91.93600  1.000 79.87000  ?  639  GLU AAZA CA  1 
ATOM   534  C C   . GLU A 1 97  ? 54.93000 39.23800 92.55800  1.000 78.63000  ?  639  GLU AAZA C   1 
ATOM   535  O O   . GLU A 1 97  ? 54.86900 39.10900 93.78400  1.000 85.88000  ?  639  GLU AAZA O   1 
ATOM   536  C CB  . GLU A 1 97  ? 54.81900 41.43600 91.41000  1.000 87.63000  ?  639  GLU AAZA CB  1 
ATOM   537  C CG  . GLU A 1 97  ? 54.34300 42.44200 92.43800  1.000 104.53000 ?  639  GLU AAZA CG  1 
ATOM   538  C CD  . GLU A 1 97  ? 53.73500 43.69700 91.80100  1.000 119.63000 ?  639  GLU AAZA CD  1 
ATOM   539  O OE1 . GLU A 1 97  ? 53.53500 43.72600 90.54800  1.000 109.29000 ?  639  GLU AAZA OE1 1 
ATOM   540  O OE2 . GLU A 1 97  ? 53.39600 44.62500 92.57800  1.000 129.02000 ?  639  GLU AAZA OE2 1 
ATOM   541  N N   . LEU A 1 98  ? 54.24900 38.45200 91.72400  1.000 76.99000  ?  640  LEU AAZA N   1 
ATOM   542  C CA  . LEU A 1 98  ? 53.44700 37.34200 92.22600  1.000 74.56000  ?  640  LEU AAZA CA  1 
ATOM   543  C C   . LEU A 1 98  ? 54.25500 36.43800 93.14300  1.000 76.50000  ?  640  LEU AAZA C   1 
ATOM   544  O O   . LEU A 1 98  ? 53.84500 36.17300 94.27600  1.000 81.96000  ?  640  LEU AAZA O   1 
ATOM   545  C CB  . LEU A 1 98  ? 52.87900 36.53300 91.06900  1.000 73.36000  ?  640  LEU AAZA CB  1 
ATOM   546  C CG  . LEU A 1 98  ? 51.96700 35.44300 91.59100  1.000 66.35000  ?  640  LEU AAZA CG  1 
ATOM   547  C CD1 . LEU A 1 98  ? 50.85500 36.14200 92.24400  1.000 64.82000  ?  640  LEU AAZA CD1 1 
ATOM   548  C CD2 . LEU A 1 98  ? 51.44700 34.58800 90.46800  1.000 62.85000  ?  640  LEU AAZA CD2 1 
ATOM   549  N N   . LEU A 1 99  ? 55.41300 35.95800 92.67300  1.000 72.38000  ?  641  LEU AAZA N   1 
ATOM   550  C CA  . LEU A 1 99  ? 56.24300 35.10900 93.52000  1.000 76.50000  ?  641  LEU AAZA CA  1 
ATOM   551  C C   . LEU A 1 99  ? 56.55800 35.76900 94.86000  1.000 80.72000  ?  641  LEU AAZA C   1 
ATOM   552  O O   . LEU A 1 99  ? 56.53400 35.11200 95.90700  1.000 82.06000  ?  641  LEU AAZA O   1 
ATOM   553  C CB  . LEU A 1 99  ? 57.54400 34.75400 92.82000  1.000 74.23000  ?  641  LEU AAZA CB  1 
ATOM   554  C CG  . LEU A 1 99  ? 58.26100 33.75400 93.72200  1.000 73.39000  ?  641  LEU AAZA CG  1 
ATOM   555  C CD1 . LEU A 1 99  ? 57.38100 32.54100 93.87400  1.000 81.79000  ?  641  LEU AAZA CD1 1 
ATOM   556  C CD2 . LEU A 1 99  ? 59.57700 33.35100 93.18000  1.000 74.50000  ?  641  LEU AAZA CD2 1 
ATOM   557  N N   . SER A 1 100 ? 56.86400 37.06400 94.84800  1.000 77.19000  ?  642  SER AAZA N   1 
ATOM   558  C CA  . SER A 1 100 ? 57.15200 37.76100 96.09100  1.000 74.53000  ?  642  SER AAZA CA  1 
ATOM   559  C C   . SER A 1 100 ? 55.94500 37.76200 97.01500  1.000 83.71000  ?  642  SER AAZA C   1 
ATOM   560  O O   . SER A 1 100 ? 56.07000 37.48300 98.21500  1.000 91.45000  ?  642  SER AAZA O   1 
ATOM   561  C CB  . SER A 1 100 ? 57.61500 39.18400 95.80600  1.000 74.20000  ?  642  SER AAZA CB  1 
ATOM   562  O OG  . SER A 1 100 ? 58.89000 39.15700 95.20500  1.000 75.51000  ?  642  SER AAZA OG  1 
ATOM   563  N N   . LEU A 1 101 ? 54.78000 38.08500 96.47300  1.000 77.11000  ?  643  LEU AAZA N   1 
ATOM   564  C CA  . LEU A 1 101 ? 53.56400 38.06900 97.31700  1.000 83.40000  ?  643  LEU AAZA CA  1 
ATOM   565  C C   . LEU A 1 101 ? 53.38500 36.65500 97.87400  1.000 87.72000  ?  643  LEU AAZA C   1 
ATOM   566  O O   . LEU A 1 101 ? 53.25700 36.52100 99.09900  1.000 90.74000  ?  643  LEU AAZA O   1 
ATOM   567  C CB  . LEU A 1 101 ? 52.38200 38.52400 96.46300  1.000 77.92000  ?  643  LEU AAZA CB  1 
ATOM   568  C CG  . LEU A 1 101 ? 52.55700 39.89500 95.81500  1.000 83.86000  ?  643  LEU AAZA CG  1 
ATOM   569  C CD1 . LEU A 1 101 ? 51.23000 40.43200 95.30900  1.000 83.84000  ?  643  LEU AAZA CD1 1 
ATOM   570  C CD2 . LEU A 1 101 ? 53.18900 40.87400 96.79100  1.000 87.43000  ?  643  LEU AAZA CD2 1 
ATOM   571  N N   . ILE A 1 102 ? 53.41800 35.64000 97.01200  1.000 82.89000  ?  644  ILE AAZA N   1 
ATOM   572  C CA  . ILE A 1 102 ? 53.25200 34.25900 97.44700  1.000 79.95000  ?  644  ILE AAZA CA  1 
ATOM   573  C C   . ILE A 1 102 ? 54.23600 33.86000 98.54300  1.000 83.87000  ?  644  ILE AAZA C   1 
ATOM   574  O O   . ILE A 1 102 ? 53.94800 32.95900 99.34100  1.000 85.96000  ?  644  ILE AAZA O   1 
ATOM   575  C CB  . ILE A 1 102 ? 53.33900 33.34500 96.21900  1.000 73.50000  ?  644  ILE AAZA CB  1 
ATOM   576  C CG1 . ILE A 1 102 ? 51.99000 33.29700 95.56700  1.000 76.33000  ?  644  ILE AAZA CG1 1 
ATOM   577  C CG2 . ILE A 1 102 ? 53.85900 31.96400 96.52000  1.000 79.32000  ?  644  ILE AAZA CG2 1 
ATOM   578  C CD1 . ILE A 1 102 ? 52.06300 32.54100 94.30100  1.000 89.50000  ?  644  ILE AAZA CD1 1 
ATOM   579  N N   . ILE A 1 103 ? 55.39500 34.50500 98.62900  1.000 82.55000  ?  645  ILE AAZA N   1 
ATOM   580  C CA  . ILE A 1 103 ? 56.26100 34.20100 99.76600  1.000 88.18000  ?  645  ILE AAZA CA  1 
ATOM   581  C C   . ILE A 1 103 ? 55.86800 35.02300 100.98700 1.000 93.80000  ?  645  ILE AAZA C   1 
ATOM   582  O O   . ILE A 1 103 ? 55.74400 34.47600 102.09000 1.000 90.31000  ?  645  ILE AAZA O   1 
ATOM   583  C CB  . ILE A 1 103 ? 57.74500 34.37300 99.40900  1.000 86.18000  ?  645  ILE AAZA CB  1 
ATOM   584  C CG1 . ILE A 1 103 ? 58.15300 33.29100 98.40300  1.000 87.99000  ?  645  ILE AAZA CG1 1 
ATOM   585  C CG2 . ILE A 1 103 ? 58.58500 34.35300 100.66300 1.000 83.07000  ?  645  ILE AAZA CG2 1 
ATOM   586  C CD1 . ILE A 1 103 ? 59.62900 33.20000 98.16400  1.000 86.03000  ?  645  ILE AAZA CD1 1 
ATOM   587  N N   . GLU A 1 104 ? 55.65400 36.33700 100.81900 1.000 94.71000  ?  646  GLU AAZA N   1 
ATOM   588  C CA  . GLU A 1 104 ? 55.08300 37.11900 101.91400 1.000 93.30000  ?  646  GLU AAZA CA  1 
ATOM   589  C C   . GLU A 1 104 ? 53.90000 36.40000 102.54500 1.000 90.51000  ?  646  GLU AAZA C   1 
ATOM   590  O O   . GLU A 1 104 ? 53.77500 36.34800 103.76900 1.000 94.21000  ?  646  GLU AAZA O   1 
ATOM   591  C CB  . GLU A 1 104 ? 54.63400 38.49400 101.43800 1.000 91.40000  ?  646  GLU AAZA CB  1 
ATOM   592  C CG  . GLU A 1 104 ? 55.66900 39.57800 101.49800 1.000 96.59000  ?  646  GLU AAZA CG  1 
ATOM   593  C CD  . GLU A 1 104 ? 55.00300 40.95100 101.64800 1.000 109.81000 ?  646  GLU AAZA CD  1 
ATOM   594  O OE1 . GLU A 1 104 ? 53.82100 40.99300 102.08600 1.000 100.37000 ?  646  GLU AAZA OE1 1 
ATOM   595  O OE2 . GLU A 1 104 ? 55.64100 41.97900 101.31500 1.000 118.61000 ?  646  GLU AAZA OE2 1 
ATOM   596  N N   . ARG A 1 105 ? 53.02900 35.82600 101.72000 1.000 90.52000  ?  647  ARG AAZA N   1 
ATOM   597  C CA  . ARG A 1 105 ? 51.90200 35.07100 102.24400 1.000 91.65000  ?  647  ARG AAZA CA  1 
ATOM   598  C C   . ARG A 1 105 ? 52.34800 33.87200 103.06300 1.000 96.92000  ?  647  ARG AAZA C   1 
ATOM   599  O O   . ARG A 1 105 ? 51.61000 33.44200 103.95100 1.000 106.09000 ?  647  ARG AAZA O   1 
ATOM   600  C CB  . ARG A 1 105 ? 50.99800 34.60700 101.10800 1.000 90.23000  ?  647  ARG AAZA CB  1 
ATOM   601  C CG  . ARG A 1 105 ? 49.70700 34.01200 101.58400 1.000 90.73000  ?  647  ARG AAZA CG  1 
ATOM   602  C CD  . ARG A 1 105 ? 48.78100 35.08300 102.13300 1.000 94.21000  ?  647  ARG AAZA CD  1 
ATOM   603  N NE  . ARG A 1 105 ? 47.43800 34.55200 102.36100 1.000 99.32000  ?  647  ARG AAZA NE  1 
ATOM   604  C CZ  . ARG A 1 105 ? 46.88000 34.42400 103.56000 1.000 97.09000  ?  647  ARG AAZA CZ  1 
ATOM   605  N NH1 . ARG A 1 105 ? 47.51100 34.81000 104.65800 1.000 95.32000  ?  647  ARG AAZA NH1 1 
ATOM   606  N NH2 . ARG A 1 105 ? 45.66200 33.89200 103.65800 1.000 91.55000  ?  647  ARG AAZA NH2 1 
ATOM   607  N N   . PHE A 1 106 ? 53.54200 33.32600 102.79800 1.000 94.11000  ?  648  PHE AAZA N   1 
ATOM   608  C CA  . PHE A 1 106 ? 54.01800 32.09500 103.44400 1.000 96.96000  ?  648  PHE AAZA CA  1 
ATOM   609  C C   . PHE A 1 106 ? 54.77400 32.33900 104.74800 1.000 99.06000  ?  648  PHE AAZA C   1 
ATOM   610  O O   . PHE A 1 106 ? 54.83500 31.42900 105.58200 1.000 99.25000  ?  648  PHE AAZA O   1 
ATOM   611  C CB  . PHE A 1 106 ? 54.90900 31.32900 102.45900 1.000 93.91000  ?  648  PHE AAZA CB  1 
ATOM   612  C CG  . PHE A 1 106 ? 55.25500 29.90200 102.85100 1.000 92.20000  ?  648  PHE AAZA CG  1 
ATOM   613  C CD1 . PHE A 1 106 ? 54.49500 28.83500 102.37900 1.000 91.12000  ?  648  PHE AAZA CD1 1 
ATOM   614  C CD2 . PHE A 1 106 ? 56.38800 29.62200 103.60300 1.000 91.22000  ?  648  PHE AAZA CD2 1 
ATOM   615  C CE1 . PHE A 1 106 ? 54.83800 27.51700 102.67300 1.000 90.42000  ?  648  PHE AAZA CE1 1 
ATOM   616  C CE2 . PHE A 1 106 ? 56.73800 28.31200 103.89800 1.000 92.00000  ?  648  PHE AAZA CE2 1 
ATOM   617  C CZ  . PHE A 1 106 ? 55.96100 27.25800 103.43100 1.000 94.13000  ?  648  PHE AAZA CZ  1 
ATOM   618  N N   . GLU A 1 107 ? 55.33000 33.53900 104.94900 1.000 100.66000 ?  649  GLU AAZA N   1 
ATOM   619  C CA  . GLU A 1 107 ? 56.14200 33.85500 106.12900 1.000 101.03000 ?  649  GLU AAZA CA  1 
ATOM   620  C C   . GLU A 1 107 ? 55.24200 34.40000 107.23800 1.000 104.03000 ?  649  GLU AAZA C   1 
ATOM   621  O O   . GLU A 1 107 ? 55.28800 35.57400 107.60700 1.000 107.11000 ?  649  GLU AAZA O   1 
ATOM   622  C CB  . GLU A 1 107 ? 57.23200 34.87100 105.79100 1.000 99.51000  ?  649  GLU AAZA CB  1 
ATOM   623  C CG  . GLU A 1 107 ? 57.91900 34.74700 104.43400 1.000 99.45000  ?  649  GLU AAZA CG  1 
ATOM   624  C CD  . GLU A 1 107 ? 58.72900 33.47100 104.21800 1.000 100.92000 ?  649  GLU AAZA CD  1 
ATOM   625  O OE1 . GLU A 1 107 ? 58.19100 32.36300 104.48000 1.000 94.09000  ?  649  GLU AAZA OE1 1 
ATOM   626  O OE2 . GLU A 1 107 ? 59.89200 33.58800 103.73200 1.000 100.35000 ?  649  GLU AAZA OE2 1 
ATOM   627  N N   . ILE A 1 108 ? 54.41200 33.51900 107.77000 1.000 106.29000 ?  650  ILE AAZA N   1 
ATOM   628  C CA  . ILE A 1 108 ? 53.47300 33.93900 108.81500 1.000 110.73000 ?  650  ILE AAZA CA  1 
ATOM   629  C C   . ILE A 1 108 ? 54.26300 34.27800 110.07600 1.000 115.03000 ?  650  ILE AAZA C   1 
ATOM   630  O O   . ILE A 1 108 ? 55.15200 33.50400 110.46100 1.000 115.45000 ?  650  ILE AAZA O   1 
ATOM   631  C CB  . ILE A 1 108 ? 52.46800 32.82700 109.09700 1.000 107.76000 ?  650  ILE AAZA CB  1 
ATOM   632  C CG1 . ILE A 1 108 ? 52.01600 32.14600 107.81400 1.000 105.63000 ?  650  ILE AAZA CG1 1 
ATOM   633  C CG2 . ILE A 1 108 ? 51.20600 33.43100 109.65700 1.000 111.08000 ?  650  ILE AAZA CG2 1 
ATOM   634  C CD1 . ILE A 1 108 ? 51.44300 33.07500 106.84900 1.000 104.28000 ?  650  ILE AAZA CD1 1 
ATOM   635  N N   . PRO A 1 109 ? 54.01000 35.39900 110.74400 1.000 120.12000 ?  651  PRO AAZA N   1 
ATOM   636  C CA  . PRO A 1 109 ? 54.60800 35.62700 112.06000 1.000 124.47000 ?  651  PRO AAZA CA  1 
ATOM   637  C C   . PRO A 1 109 ? 53.70700 35.13500 113.19500 1.000 135.47000 ?  651  PRO AAZA C   1 
ATOM   638  O O   . PRO A 1 109 ? 52.53500 34.78300 113.00000 1.000 129.83000 ?  651  PRO AAZA O   1 
ATOM   639  C CB  . PRO A 1 109 ? 54.79100 37.15100 112.09400 1.000 119.70000 ?  651  PRO AAZA CB  1 
ATOM   640  C CG  . PRO A 1 109 ? 53.67100 37.66800 111.29500 1.000 117.48000 ?  651  PRO AAZA CG  1 
ATOM   641  C CD  . PRO A 1 109 ? 53.39600 36.63000 110.21600 1.000 122.08000 ?  651  PRO AAZA CD  1 
ATOM   642  N N   . GLU A 1 110 ? 54.30200 35.09900 114.41200 1.000 143.16000 ?  652  GLU AAZA N   1 
ATOM   643  C CA  . GLU A 1 110 ? 53.71300 34.56100 115.64200 1.000 141.90000 ?  652  GLU AAZA CA  1 
ATOM   644  C C   . GLU A 1 110 ? 53.33000 35.68600 116.59700 1.000 145.23000 ?  652  GLU AAZA C   1 
ATOM   645  O O   . GLU A 1 110 ? 54.14400 36.58800 116.83600 1.000 149.48000 ?  652  GLU AAZA O   1 
ATOM   646  C CB  . GLU A 1 110 ? 54.70100 33.60600 116.33100 1.000 141.18000 ?  652  GLU AAZA CB  1 
ATOM   647  C CG  . GLU A 1 110 ? 54.87200 32.23700 115.66300 1.000 142.24000 ?  652  GLU AAZA CG  1 
ATOM   648  C CD  . GLU A 1 110 ? 53.80100 31.22200 116.08000 1.000 146.22000 ?  652  GLU AAZA CD  1 
ATOM   649  O OE1 . GLU A 1 110 ? 52.59000 31.50700 115.92800 1.000 142.48000 ?  652  GLU AAZA OE1 1 
ATOM   650  O OE2 . GLU A 1 110 ? 54.17400 30.12700 116.56400 1.000 147.74000 ?  652  GLU AAZA OE2 1 
ATOM   651  N N   . PRO A 1 111 ? 52.11400 35.66300 117.17900 1.000 151.25000 ?  653  PRO AAZA N   1 
ATOM   652  C CA  . PRO A 1 111 ? 51.62600 36.70500 118.09800 1.000 153.82000 ?  653  PRO AAZA CA  1 
ATOM   653  C C   . PRO A 1 111 ? 52.55200 36.97800 119.28300 1.000 151.46000 ?  653  PRO AAZA C   1 
ATOM   654  O O   . PRO A 1 111 ? 52.79500 36.06200 120.06900 1.000 156.20000 ?  653  PRO AAZA O   1 
ATOM   655  C CB  . PRO A 1 111 ? 50.27900 36.14100 118.57900 1.000 159.46000 ?  653  PRO AAZA CB  1 
ATOM   656  C CG  . PRO A 1 111 ? 49.84800 35.20600 117.48100 1.000 153.74000 ?  653  PRO AAZA CG  1 
ATOM   657  C CD  . PRO A 1 111 ? 51.12400 34.58500 116.99600 1.000 152.79000 ?  653  PRO AAZA CD  1 
ATOM   658  N N   . SER A 1 129 ? 49.08400 30.72700 123.85000 1.000 145.07000 ?  671  SER AAZA N   1 
ATOM   659  C CA  . SER A 1 129 ? 49.59000 29.39400 123.53500 1.000 152.50000 ?  671  SER AAZA CA  1 
ATOM   660  C C   . SER A 1 129 ? 48.45700 28.37100 123.39900 1.000 158.04000 ?  671  SER AAZA C   1 
ATOM   661  O O   . SER A 1 129 ? 48.63100 27.31900 122.77400 1.000 157.12000 ?  671  SER AAZA O   1 
ATOM   662  C CB  . SER A 1 129 ? 50.59100 28.92700 124.60100 1.000 146.37000 ?  671  SER AAZA CB  1 
ATOM   663  O OG  . SER A 1 129 ? 51.10000 27.63300 124.30600 1.000 135.63000 ?  671  SER AAZA OG  1 
ATOM   664  N N   . ALA A 1 130 ? 47.29800 28.67700 123.98800 1.000 159.61000 ?  672  ALA AAZA N   1 
ATOM   665  C CA  . ALA A 1 130 ? 46.15100 27.77500 123.92700 1.000 159.97000 ?  672  ALA AAZA CA  1 
ATOM   666  C C   . ALA A 1 130 ? 45.28800 28.05300 122.69900 1.000 157.99000 ?  672  ALA AAZA C   1 
ATOM   667  O O   . ALA A 1 130 ? 44.93100 27.12800 121.95900 1.000 152.04000 ?  672  ALA AAZA O   1 
ATOM   668  C CB  . ALA A 1 130 ? 45.32100 27.89000 125.21100 1.000 158.33000 ?  672  ALA AAZA CB  1 
ATOM   669  N N   . GLU A 1 131 ? 44.94000 29.32300 122.48500 1.000 159.64000 ?  673  GLU AAZA N   1 
ATOM   670  C CA  . GLU A 1 131 ? 44.36200 29.79500 121.23500 1.000 157.43000 ?  673  GLU AAZA CA  1 
ATOM   671  C C   . GLU A 1 131 ? 45.41800 30.42800 120.32700 1.000 153.06000 ?  673  GLU AAZA C   1 
ATOM   672  O O   . GLU A 1 131 ? 45.07800 31.18300 119.40800 1.000 149.47000 ?  673  GLU AAZA O   1 
ATOM   673  C CB  . GLU A 1 131 ? 43.20600 30.75900 121.52300 1.000 160.07000 ?  673  GLU AAZA CB  1 
ATOM   674  C CG  . GLU A 1 131 ? 41.99100 30.06500 122.15900 1.000 156.06000 ?  673  GLU AAZA CG  1 
ATOM   675  C CD  . GLU A 1 131 ? 40.94600 31.03600 122.69000 1.000 163.54000 ?  673  GLU AAZA CD  1 
ATOM   676  O OE1 . GLU A 1 131 ? 41.32300 32.12400 123.17900 1.000 162.00000 ?  673  GLU AAZA OE1 1 
ATOM   677  O OE2 . GLU A 1 131 ? 39.74300 30.70600 122.62100 1.000 164.26000 ?  673  GLU AAZA OE2 1 
ATOM   678  N N   . LEU A 1 132 ? 46.69700 30.15200 120.59500 1.000 154.38000 ?  674  LEU AAZA N   1 
ATOM   679  C CA  . LEU A 1 132 ? 47.73800 30.21000 119.58100 1.000 153.40000 ?  674  LEU AAZA CA  1 
ATOM   680  C C   . LEU A 1 132 ? 48.09300 28.83000 119.04500 1.000 147.46000 ?  674  LEU AAZA C   1 
ATOM   681  O O   . LEU A 1 132 ? 48.80000 28.73900 118.03700 1.000 144.58000 ?  674  LEU AAZA O   1 
ATOM   682  C CB  . LEU A 1 132 ? 49.00300 30.89900 120.11800 1.000 152.28000 ?  674  LEU AAZA CB  1 
ATOM   683  C CG  . LEU A 1 132 ? 48.77500 32.21600 120.86500 1.000 157.37000 ?  674  LEU AAZA CG  1 
ATOM   684  C CD1 . LEU A 1 132 ? 50.08500 32.74300 121.44100 1.000 157.45000 ?  674  LEU AAZA CD1 1 
ATOM   685  C CD2 . LEU A 1 132 ? 48.09400 33.26000 119.97500 1.000 151.81000 ?  674  LEU AAZA CD2 1 
ATOM   686  N N   . LYS A 1 133 ? 47.63000 27.75800 119.69600 1.000 146.81000 ?  675  LYS AAZA N   1 
ATOM   687  C CA  . LYS A 1 133 ? 47.71900 26.43500 119.08700 1.000 146.11000 ?  675  LYS AAZA CA  1 
ATOM   688  C C   . LYS A 1 133 ? 46.76400 26.31700 117.90700 1.000 141.85000 ?  675  LYS AAZA C   1 
ATOM   689  O O   . LYS A 1 133 ? 47.12700 25.74900 116.86900 1.000 138.53000 ?  675  LYS AAZA O   1 
ATOM   690  C CB  . LYS A 1 133 ? 47.43200 25.34300 120.12400 1.000 150.50000 ?  675  LYS AAZA CB  1 
ATOM   691  C CG  . LYS A 1 133 ? 46.66400 24.11900 119.58200 1.000 148.05000 ?  675  LYS AAZA CG  1 
ATOM   692  C CD  . LYS A 1 133 ? 47.49500 23.26500 118.60200 1.000 144.75000 ?  675  LYS AAZA CD  1 
ATOM   693  C CE  . LYS A 1 133 ? 46.62800 22.73000 117.46100 1.000 135.70000 ?  675  LYS AAZA CE  1 
ATOM   694  N NZ  . LYS A 1 133 ? 47.43800 22.10400 116.38600 1.000 125.83000 ?  675  LYS AAZA NZ  1 
ATOM   695  N N   . ARG A 1 134 ? 45.56100 26.87400 118.02200 1.000 144.75000 ?  676  ARG AAZA N   1 
ATOM   696  C CA  . ARG A 1 134 ? 44.67300 26.86400 116.83100 1.000 143.82000 ?  676  ARG AAZA CA  1 
ATOM   697  C C   . ARG A 1 134 ? 45.41400 27.59300 115.71400 1.000 141.73000 ?  676  ARG AAZA C   1 
ATOM   698  O O   . ARG A 1 134 ? 45.33600 27.14000 114.55500 1.000 133.72000 ?  676  ARG AAZA O   1 
ATOM   699  C CB  . ARG A 1 134 ? 43.34900 27.56000 117.15000 1.000 142.58000 ?  676  ARG AAZA CB  1 
ATOM   700  C CG  . ARG A 1 134 ? 43.49900 28.99100 117.64500 1.000 145.84000 ?  676  ARG AAZA CG  1 
ATOM   701  C CD  . ARG A 1 134 ? 42.16100 29.68100 117.82600 1.000 149.76000 ?  676  ARG AAZA CD  1 
ATOM   702  N NE  . ARG A 1 134 ? 42.28900 30.98400 118.46400 1.000 160.78000 ?  676  ARG AAZA NE  1 
ATOM   703  C CZ  . ARG A 1 134 ? 41.90200 32.13300 117.92200 1.000 161.38000 ?  676  ARG AAZA CZ  1 
ATOM   704  N NH1 . ARG A 1 134 ? 41.52600 32.17500 116.65600 1.000 157.04000 ?  676  ARG AAZA NH1 1 
ATOM   705  N NH2 . ARG A 1 134 ? 41.89400 33.23700 118.64800 1.000 152.79000 ?  676  ARG AAZA NH2 1 
ATOM   706  N N   . PHE A 1 135 ? 46.12000 28.66500 116.06600 1.000 141.97000 ?  677  PHE AAZA N   1 
ATOM   707  C CA  . PHE A 1 135 ? 46.85900 29.47300 115.10700 1.000 135.67000 ?  677  PHE AAZA CA  1 
ATOM   708  C C   . PHE A 1 135 ? 47.98200 28.68900 114.43200 1.000 127.61000 ?  677  PHE AAZA C   1 
ATOM   709  O O   . PHE A 1 135 ? 49.03000 29.25000 114.10900 1.000 125.12000 ?  677  PHE AAZA O   1 
ATOM   710  C CB  . PHE A 1 135 ? 47.39400 30.71100 115.83200 1.000 138.73000 ?  677  PHE AAZA CB  1 
ATOM   711  C CG  . PHE A 1 135 ? 47.98300 31.73700 114.92700 1.000 141.00000 ?  677  PHE AAZA CG  1 
ATOM   712  C CD1 . PHE A 1 135 ? 47.19400 32.40100 114.00300 1.000 139.29000 ?  677  PHE AAZA CD1 1 
ATOM   713  C CD2 . PHE A 1 135 ? 49.33300 32.05100 115.01300 1.000 139.04000 ?  677  PHE AAZA CD2 1 
ATOM   714  C CE1 . PHE A 1 135 ? 47.74900 33.34700 113.16800 1.000 136.94000 ?  677  PHE AAZA CE1 1 
ATOM   715  C CE2 . PHE A 1 135 ? 49.89500 32.99200 114.18400 1.000 135.69000 ?  677  PHE AAZA CE2 1 
ATOM   716  C CZ  . PHE A 1 135 ? 49.10900 33.63800 113.26300 1.000 134.71000 ?  677  PHE AAZA CZ  1 
ATOM   717  N N   . ARG A 1 136 ? 47.75100 27.40100 114.22000 1.000 125.38000 ?  678  ARG AAZA N   1 
ATOM   718  C CA  . ARG A 1 136 ? 48.77400 26.56000 113.56000 1.000 118.91000 ?  678  ARG AAZA CA  1 
ATOM   719  C C   . ARG A 1 136 ? 48.02100 25.42500 112.88500 1.000 118.83000 ?  678  ARG AAZA C   1 
ATOM   720  O O   . ARG A 1 136 ? 48.30300 25.13000 111.71600 1.000 119.31000 ?  678  ARG AAZA O   1 
ATOM   721  C CB  . ARG A 1 136 ? 49.74800 26.01900 114.60500 1.000 122.91000 ?  678  ARG AAZA CB  1 
ATOM   722  C CG  . ARG A 1 136 ? 51.17600 25.84100 114.11100 1.000 128.12000 ?  678  ARG AAZA CG  1 
ATOM   723  C CD  . ARG A 1 136 ? 51.94200 27.14900 114.12500 1.000 140.22000 ?  678  ARG AAZA CD  1 
ATOM   724  N NE  . ARG A 1 136 ? 53.36100 26.95900 113.85900 1.000 145.37000 ?  678  ARG AAZA NE  1 
ATOM   725  C CZ  . ARG A 1 136 ? 54.25400 27.94000 113.79800 1.000 143.71000 ?  678  ARG AAZA CZ  1 
ATOM   726  N NH1 . ARG A 1 136 ? 53.85400 29.19800 113.79100 1.000 138.21000 ?  678  ARG AAZA NH1 1 
ATOM   727  N NH2 . ARG A 1 136 ? 55.54400 27.65800 113.73900 1.000 138.79000 ?  678  ARG AAZA NH2 1 
ATOM   728  N N   . LYS A 1 137 ? 47.08500 24.83400 113.62000 1.000 125.05000 ?  679  LYS AAZA N   1 
ATOM   729  C CA  . LYS A 1 137 ? 46.26800 23.73800 113.05200 1.000 130.32000 ?  679  LYS AAZA CA  1 
ATOM   730  C C   . LYS A 1 137 ? 45.29100 24.35300 112.05700 1.000 129.86000 ?  679  LYS AAZA C   1 
ATOM   731  O O   . LYS A 1 137 ? 45.09400 23.76100 110.98200 1.000 122.54000 ?  679  LYS AAZA O   1 
ATOM   732  C CB  . LYS A 1 137 ? 45.49900 23.03100 114.16700 1.000 134.26000 ?  679  LYS AAZA CB  1 
ATOM   733  C CG  . LYS A 1 137 ? 44.41800 22.06600 113.69900 1.000 137.79000 ?  679  LYS AAZA CG  1 
ATOM   734  C CD  . LYS A 1 137 ? 44.96400 20.77600 113.12800 1.000 139.47000 ?  679  LYS AAZA CD  1 
ATOM   735  C CE  . LYS A 1 137 ? 45.67600 19.93000 114.16200 1.000 140.55000 ?  679  LYS AAZA CE  1 
ATOM   736  N NZ  . LYS A 1 137 ? 46.06800 18.60800 113.61800 1.000 136.86000 ?  679  LYS AAZA NZ  1 
ATOM   737  N N   . GLU A 1 138 ? 44.70600 25.49800 112.41100 1.000 130.65000 ?  680  GLU AAZA N   1 
ATOM   738  C CA  . GLU A 1 138 ? 43.66700 26.07000 111.51400 1.000 127.63000 ?  680  GLU AAZA CA  1 
ATOM   739  C C   . GLU A 1 138 ? 44.14900 27.19000 110.59200 1.000 127.09000 ?  680  GLU AAZA C   1 
ATOM   740  O O   . GLU A 1 138 ? 43.45200 27.44800 109.59800 1.000 127.41000 ?  680  GLU AAZA O   1 
ATOM   741  C CB  . GLU A 1 138 ? 42.56500 26.71100 112.35700 1.000 137.07000 ?  680  GLU AAZA CB  1 
ATOM   742  C CG  . GLU A 1 138 ? 42.97600 28.03700 112.97000 1.000 138.61000 ?  680  GLU AAZA CG  1 
ATOM   743  C CD  . GLU A 1 138 ? 41.88600 28.75700 113.74400 1.000 141.99000 ?  680  GLU AAZA CD  1 
ATOM   744  O OE1 . GLU A 1 138 ? 40.76900 28.21400 113.83200 1.000 145.33000 ?  680  GLU AAZA OE1 1 
ATOM   745  O OE2 . GLU A 1 138 ? 42.15700 29.86300 114.25100 1.000 141.20000 ?  680  GLU AAZA OE2 1 
ATOM   746  N N   . TYR A 1 139 ? 45.25000 27.86600 110.91300 1.000 123.22000 ?  681  TYR AAZA N   1 
ATOM   747  C CA  . TYR A 1 139 ? 45.62300 29.02400 110.06000 1.000 118.72000 ?  681  TYR AAZA CA  1 
ATOM   748  C C   . TYR A 1 139 ? 46.91000 28.68600 109.31200 1.000 111.90000 ?  681  TYR AAZA C   1 
ATOM   749  O O   . TYR A 1 139 ? 46.83700 28.16000 108.18600 1.000 103.56000 ?  681  TYR AAZA O   1 
ATOM   750  C CB  . TYR A 1 139 ? 45.82800 30.31500 110.85200 1.000 109.16000 ?  681  TYR AAZA CB  1 
ATOM   751  C CG  . TYR A 1 139 ? 45.73100 31.57600 110.03200 1.000 114.79000 ?  681  TYR AAZA CG  1 
ATOM   752  C CD1 . TYR A 1 139 ? 45.34500 31.53800 108.70300 1.000 107.37000 ?  681  TYR AAZA CD1 1 
ATOM   753  C CD2 . TYR A 1 139 ? 46.03800 32.80900 110.58000 1.000 115.48000 ?  681  TYR AAZA CD2 1 
ATOM   754  C CE1 . TYR A 1 139 ? 45.25300 32.69300 107.94500 1.000 103.71000 ?  681  TYR AAZA CE1 1 
ATOM   755  C CE2 . TYR A 1 139 ? 45.95700 33.97300 109.83500 1.000 110.48000 ?  681  TYR AAZA CE2 1 
ATOM   756  C CZ  . TYR A 1 139 ? 45.56300 33.91600 108.51200 1.000 107.91000 ?  681  TYR AAZA CZ  1 
ATOM   757  O OH  . TYR A 1 139 ? 45.48100 35.06800 107.77000 1.000 104.25000 ?  681  TYR AAZA OH  1 
ATOM   758  N N   . ILE A 1 140 ? 48.05300 28.97600 109.92900 1.000 110.92000 ?  682  ILE AAZA N   1 
ATOM   759  C CA  . ILE A 1 140 ? 49.34300 28.80100 109.19100 1.000 105.95000 ?  682  ILE AAZA CA  1 
ATOM   760  C C   . ILE A 1 140 ? 49.32800 27.51600 108.35900 1.000 103.26000 ?  682  ILE AAZA C   1 
ATOM   761  O O   . ILE A 1 140 ? 49.84700 27.55200 107.23300 1.000 102.97000 ?  682  ILE AAZA O   1 
ATOM   762  C CB  . ILE A 1 140 ? 50.53900 28.83600 110.16100 1.000 100.56000 ?  682  ILE AAZA CB  1 
ATOM   763  C CG1 . ILE A 1 140 ? 51.85800 29.07600 109.42600 1.000 100.83000 ?  682  ILE AAZA CG1 1 
ATOM   764  C CG2 . ILE A 1 140 ? 50.59100 27.57400 111.00400 1.000 93.57000  ?  682  ILE AAZA CG2 1 
ATOM   765  C CD1 . ILE A 1 140 ? 53.05500 29.17800 110.34100 1.000 109.27000 ?  682  ILE AAZA CD1 1 
ATOM   766  N N   . GLN A 1 141 ? 48.77600 26.42600 108.88100 1.000 103.36000 ?  683  GLN AAZA N   1 
ATOM   767  C CA  . GLN A 1 141 ? 48.86200 25.16000 108.10900 1.000 105.49000 ?  683  GLN AAZA CA  1 
ATOM   768  C C   . GLN A 1 141 ? 48.08800 25.32300 106.79900 1.000 107.65000 ?  683  GLN AAZA C   1 
ATOM   769  O O   . GLN A 1 141 ? 48.73300 25.24200 105.74100 1.000 108.32000 ?  683  GLN AAZA O   1 
ATOM   770  C CB  . GLN A 1 141 ? 48.36200 23.95800 108.91000 1.000 112.20000 ?  683  GLN AAZA CB  1 
ATOM   771  C CG  . GLN A 1 141 ? 48.52800 22.64000 108.16800 1.000 110.20000 ?  683  GLN AAZA CG  1 
ATOM   772  C CD  . GLN A 1 141 ? 48.10700 21.45600 109.00100 1.000 116.54000 ?  683  GLN AAZA CD  1 
ATOM   773  O OE1 . GLN A 1 141 ? 48.18000 20.30900 108.56500 1.000 126.70000 ?  683  GLN AAZA OE1 1 
ATOM   774  N NE2 . GLN A 1 141 ? 47.66000 21.72700 110.21600 1.000 108.21000 ?  683  GLN AAZA NE2 1 
ATOM   775  N N   . PRO A 1 142 ? 46.75600 25.54200 106.79100 1.000 105.43000 ?  684  PRO AAZA N   1 
ATOM   776  C CA  . PRO A 1 142 ? 46.03400 25.77200 105.52500 1.000 108.48000 ?  684  PRO AAZA CA  1 
ATOM   777  C C   . PRO A 1 142 ? 46.66000 26.81000 104.58600 1.000 104.52000 ?  684  PRO AAZA C   1 
ATOM   778  O O   . PRO A 1 142 ? 46.77500 26.54900 103.38300 1.000 100.29000 ?  684  PRO AAZA O   1 
ATOM   779  C CB  . PRO A 1 142 ? 44.64700 26.22400 106.00100 1.000 107.43000 ?  684  PRO AAZA CB  1 
ATOM   780  C CG  . PRO A 1 142 ? 44.46500 25.54300 107.26500 1.000 108.29000 ?  684  PRO AAZA CG  1 
ATOM   781  C CD  . PRO A 1 142 ? 45.81300 25.45700 107.92200 1.000 108.96000 ?  684  PRO AAZA CD  1 
ATOM   782  N N   . VAL A 1 143 ? 47.02300 27.99300 105.10000 1.000 102.95000 ?  685  VAL AAZA N   1 
ATOM   783  C CA  . VAL A 1 143 ? 47.64500 29.01700 104.26000 1.000 91.44000  ?  685  VAL AAZA CA  1 
ATOM   784  C C   . VAL A 1 143 ? 48.85600 28.43300 103.55500 1.000 92.51000  ?  685  VAL AAZA C   1 
ATOM   785  O O   . VAL A 1 143 ? 48.86600 28.26100 102.33300 1.000 96.54000  ?  685  VAL AAZA O   1 
ATOM   786  C CB  . VAL A 1 143 ? 48.01400 30.25800 105.09200 1.000 94.25000  ?  685  VAL AAZA CB  1 
ATOM   787  C CG1 . VAL A 1 143 ? 49.01800 31.10900 104.37400 1.000 92.32000  ?  685  VAL AAZA CG1 1 
ATOM   788  C CG2 . VAL A 1 143 ? 46.78100 31.08800 105.35500 1.000 102.60000 ?  685  VAL AAZA CG2 1 
ATOM   789  N N   . GLN A 1 144 ? 49.87800 28.07000 104.33000 1.000 95.50000  ?  686  GLN AAZA N   1 
ATOM   790  C CA  . GLN A 1 144 ? 51.10100 27.51100 103.76100 1.000 98.51000  ?  686  GLN AAZA CA  1 
ATOM   791  C C   . GLN A 1 144 ? 50.81000 26.33900 102.82900 1.000 95.25000  ?  686  GLN AAZA C   1 
ATOM   792  O O   . GLN A 1 144 ? 51.48000 26.16600 101.80300 1.000 89.09000  ?  686  GLN AAZA O   1 
ATOM   793  C CB  . GLN A 1 144 ? 52.03400 27.07200 104.89200 1.000 97.96000  ?  686  GLN AAZA CB  1 
ATOM   794  C CG  . GLN A 1 144 ? 52.74100 28.21000 105.60500 1.000 94.41000  ?  686  GLN AAZA CG  1 
ATOM   795  C CD  . GLN A 1 144 ? 53.87600 27.69500 106.46300 1.000 99.74000  ?  686  GLN AAZA CD  1 
ATOM   796  O OE1 . GLN A 1 144 ? 54.29500 26.55000 106.32000 1.000 96.96000  ?  686  GLN AAZA OE1 1 
ATOM   797  N NE2 . GLN A 1 144 ? 54.36400 28.52600 107.37600 1.000 108.67000 ?  686  GLN AAZA NE2 1 
ATOM   798  N N   . LEU A 1 145 ? 49.81500 25.52900 103.16100 1.000 96.89000  ?  687  LEU AAZA N   1 
ATOM   799  C CA  . LEU A 1 145 ? 49.48900 24.44100 102.26900 1.000 95.24000  ?  687  LEU AAZA CA  1 
ATOM   800  C C   . LEU A 1 145 ? 48.82000 24.95700 101.00500 1.000 92.94000  ?  687  LEU AAZA C   1 
ATOM   801  O O   . LEU A 1 145 ? 48.86500 24.27800 99.97300  1.000 95.63000  ?  687  LEU AAZA O   1 
ATOM   802  C CB  . LEU A 1 145 ? 48.58300 23.44100 102.97500 1.000 96.33000  ?  687  LEU AAZA CB  1 
ATOM   803  C CG  . LEU A 1 145 ? 48.84600 22.01100 102.55000 1.000 99.70000  ?  687  LEU AAZA CG  1 
ATOM   804  C CD1 . LEU A 1 145 ? 50.33000 21.73600 102.78000 1.000 102.96000 ?  687  LEU AAZA CD1 1 
ATOM   805  C CD2 . LEU A 1 145 ? 47.95700 21.05700 103.30500 1.000 102.80000 ?  687  LEU AAZA CD2 1 
ATOM   806  N N   . ARG A 1 146 ? 48.19900 26.14300 101.05700 1.000 91.38000  ?  688  ARG AAZA N   1 
ATOM   807  C CA  . ARG A 1 146 ? 47.55700 26.69900 99.87500  1.000 89.15000  ?  688  ARG AAZA CA  1 
ATOM   808  C C   . ARG A 1 146 ? 48.46400 27.61300 99.06700  1.000 89.87000  ?  688  ARG AAZA C   1 
ATOM   809  O O   . ARG A 1 146 ? 48.20700 27.80800 97.87400  1.000 92.73000  ?  688  ARG AAZA O   1 
ATOM   810  C CB  . ARG A 1 146 ? 46.25500 27.41800 100.23400 1.000 84.02000  ?  688  ARG AAZA CB  1 
ATOM   811  C CG  . ARG A 1 146 ? 45.07400 26.45900 100.12400 1.000 92.70000  ?  688  ARG AAZA CG  1 
ATOM   812  C CD  . ARG A 1 146 ? 43.73500 27.13000 100.29500 1.000 98.81000  ?  688  ARG AAZA CD  1 
ATOM   813  N NE  . ARG A 1 146 ? 43.24900 27.08100 101.67100 1.000 108.14000 ?  688  ARG AAZA NE  1 
ATOM   814  C CZ  . ARG A 1 146 ? 42.52900 26.09300 102.18600 1.000 104.31000 ?  688  ARG AAZA CZ  1 
ATOM   815  N NH1 . ARG A 1 146 ? 42.18300 25.04100 101.46000 1.000 102.43000 ?  688  ARG AAZA NH1 1 
ATOM   816  N NH2 . ARG A 1 146 ? 42.13900 26.16800 103.45900 1.000 100.72000 ?  688  ARG AAZA NH2 1 
ATOM   817  N N   . VAL A 1 147 ? 49.53000 28.14800 99.65800  1.000 82.37000  ?  689  VAL AAZA N   1 
ATOM   818  C CA  . VAL A 1 147 ? 50.61400 28.67300 98.83600  1.000 80.41000  ?  689  VAL AAZA CA  1 
ATOM   819  C C   . VAL A 1 147 ? 51.20600 27.55300 97.98200  1.000 81.12000  ?  689  VAL AAZA C   1 
ATOM   820  O O   . VAL A 1 147 ? 51.21500 27.62500 96.75200  1.000 83.73000  ?  689  VAL AAZA O   1 
ATOM   821  C CB  . VAL A 1 147 ? 51.67900 29.36100 99.70800  1.000 83.85000  ?  689  VAL AAZA CB  1 
ATOM   822  C CG1 . VAL A 1 147 ? 53.00400 29.47500 98.97500  1.000 73.97000  ?  689  VAL AAZA CG1 1 
ATOM   823  C CG2 . VAL A 1 147 ? 51.19100 30.74200 100.16300 1.000 84.73000  ?  689  VAL AAZA CG2 1 
ATOM   824  N N   . LEU A 1 148 ? 51.65200 26.47000 98.60900  1.000 84.24000  ?  690  LEU AAZA N   1 
ATOM   825  C CA  . LEU A 1 148 ? 52.25300 25.39900 97.82000  1.000 86.64000  ?  690  LEU AAZA CA  1 
ATOM   826  C C   . LEU A 1 148 ? 51.29800 24.81700 96.78000  1.000 89.04000  ?  690  LEU AAZA C   1 
ATOM   827  O O   . LEU A 1 148 ? 51.76000 24.30900 95.75300  1.000 91.99000  ?  690  LEU AAZA O   1 
ATOM   828  C CB  . LEU A 1 148 ? 52.79100 24.28200 98.71600  1.000 93.29000  ?  690  LEU AAZA CB  1 
ATOM   829  C CG  . LEU A 1 148 ? 54.01400 24.61600 99.56700  1.000 100.57000 ?  690  LEU AAZA CG  1 
ATOM   830  C CD1 . LEU A 1 148 ? 54.72300 23.33300 99.89400  1.000 111.13000 ?  690  LEU AAZA CD1 1 
ATOM   831  C CD2 . LEU A 1 148 ? 54.96100 25.57100 98.85200  1.000 96.26000  ?  690  LEU AAZA CD2 1 
ATOM   832  N N   . ASN A 1 149 ? 49.97900 24.87200 96.99100  1.000 85.43000  ?  691  ASN AAZA N   1 
ATOM   833  C CA  . ASN A 1 149 ? 49.11600 24.38900 95.91600  1.000 89.02000  ?  691  ASN AAZA CA  1 
ATOM   834  C C   . ASN A 1 149 ? 49.15300 25.34700 94.72900  1.000 93.37000  ?  691  ASN AAZA C   1 
ATOM   835  O O   . ASN A 1 149 ? 49.14600 24.91600 93.56100  1.000 90.27000  ?  691  ASN AAZA O   1 
ATOM   836  C CB  . ASN A 1 149 ? 47.67400 24.20700 96.37500  1.000 90.08000  ?  691  ASN AAZA CB  1 
ATOM   837  C CG  . ASN A 1 149 ? 46.74800 23.79600 95.21600  1.000 95.51000  ?  691  ASN AAZA CG  1 
ATOM   838  O OD1 . ASN A 1 149 ? 46.85100 22.68300 94.68600  1.000 92.74000  ?  691  ASN AAZA OD1 1 
ATOM   839  N ND2 . ASN A 1 149 ? 45.86800 24.70300 94.80400  1.000 95.60000  ?  691  ASN AAZA ND2 1 
ATOM   840  N N   . VAL A 1 150 ? 49.16800 26.65400 95.01300  1.000 90.17000  ?  692  VAL AAZA N   1 
ATOM   841  C CA  . VAL A 1 150 ? 49.40400 27.63900 93.96500  1.000 80.93000  ?  692  VAL AAZA CA  1 
ATOM   842  C C   . VAL A 1 150 ? 50.67000 27.29500 93.20000  1.000 81.73000  ?  692  VAL AAZA C   1 
ATOM   843  O O   . VAL A 1 150 ? 50.62700 27.02900 91.99400  1.000 85.05000  ?  692  VAL AAZA O   1 
ATOM   844  C CB  . VAL A 1 150 ? 49.44800 29.05900 94.55600  1.000 75.80000  ?  692  VAL AAZA CB  1 
ATOM   845  C CG1 . VAL A 1 150 ? 50.04800 29.97100 93.58900  1.000 74.80000  ?  692  VAL AAZA CG1 1 
ATOM   846  C CG2 . VAL A 1 150 ? 48.03600 29.55800 94.79900  1.000 77.43000  ?  692  VAL AAZA CG2 1 
ATOM   847  N N   . CYS A 1 151 ? 51.80600 27.24600 93.89900  1.000 82.90000  ?  693  CYS AAZA N   1 
ATOM   848  C CA  . CYS A 1 151 ? 53.08300 26.96600 93.24700  1.000 78.47000  ?  693  CYS AAZA CA  1 
ATOM   849  C C   . CYS A 1 151 ? 53.01100 25.73000 92.37200  1.000 80.04000  ?  693  CYS AAZA C   1 
ATOM   850  O O   . CYS A 1 151 ? 53.58500 25.71300 91.28400  1.000 82.65000  ?  693  CYS AAZA O   1 
ATOM   851  C CB  . CYS A 1 151 ? 54.18300 26.80400 94.28700  1.000 81.83000  ?  693  CYS AAZA CB  1 
ATOM   852  S SG  . CYS A 1 151 ? 54.64800 28.36700 95.03800  1.000 96.91000  ?  693  CYS AAZA SG  1 
ATOM   853  N N   . ARG A 1 152 ? 52.30300 24.68700 92.81300  1.000 82.82000  ?  694  ARG AAZA N   1 
ATOM   854  C CA  . ARG A 1 152 ? 52.19400 23.50400 91.96900  1.000 84.66000  ?  694  ARG AAZA CA  1 
ATOM   855  C C   . ARG A 1 152 ? 51.36200 23.79600 90.72600  1.000 85.99000  ?  694  ARG AAZA C   1 
ATOM   856  O O   . ARG A 1 152 ? 51.77400 23.47800 89.60600  1.000 84.81000  ?  694  ARG AAZA O   1 
ATOM   857  C CB  . ARG A 1 152 ? 51.59700 22.32400 92.73000  1.000 90.51000  ?  694  ARG AAZA CB  1 
ATOM   858  C CG  . ARG A 1 152 ? 51.50500 21.09200 91.82600  1.000 96.94000  ?  694  ARG AAZA CG  1 
ATOM   859  C CD  . ARG A 1 152 ? 51.00900 19.83300 92.52600  1.000 103.70000 ?  694  ARG AAZA CD  1 
ATOM   860  N NE  . ARG A 1 152 ? 49.64700 19.98700 93.02700  1.000 112.03000 ?  694  ARG AAZA NE  1 
ATOM   861  C CZ  . ARG A 1 152 ? 48.55600 20.01900 92.26600  1.000 113.29000 ?  694  ARG AAZA CZ  1 
ATOM   862  N NH1 . ARG A 1 152 ? 48.63000 19.96300 90.94200  1.000 107.10000 ?  694  ARG AAZA NH1 1 
ATOM   863  N NH2 . ARG A 1 152 ? 47.36000 20.11400 92.84800  1.000 115.16000 ?  694  ARG AAZA NH2 1 
ATOM   864  N N   . HIS A 1 153 ? 50.18000 24.39200 90.90000  1.000 88.35000  ?  695  HIS AAZA N   1 
ATOM   865  C CA  . HIS A 1 153 ? 49.37600 24.74100 89.73100  1.000 86.72000  ?  695  HIS AAZA CA  1 
ATOM   866  C C   . HIS A 1 153 ? 50.12800 25.68200 88.81400  1.000 78.76000  ?  695  HIS AAZA C   1 
ATOM   867  O O   . HIS A 1 153 ? 50.13200 25.49900 87.59600  1.000 82.30000  ?  695  HIS AAZA O   1 
ATOM   868  C CB  . HIS A 1 153 ? 48.05300 25.37200 90.15400  1.000 90.76000  ?  695  HIS AAZA CB  1 
ATOM   869  C CG  . HIS A 1 153 ? 47.00400 24.37300 90.51400  1.000 97.27000  ?  695  HIS AAZA CG  1 
ATOM   870  N ND1 . HIS A 1 153 ? 46.76100 23.98300 91.81400  1.000 98.91000  ?  695  HIS AAZA ND1 1 
ATOM   871  C CD2 . HIS A 1 153 ? 46.15400 23.66000 89.73800  1.000 98.18000  ?  695  HIS AAZA CD2 1 
ATOM   872  C CE1 . HIS A 1 153 ? 45.78700 23.09000 91.82400  1.000 105.89000 ?  695  HIS AAZA CE1 1 
ATOM   873  N NE2 . HIS A 1 153 ? 45.40600 22.87100 90.57700  1.000 103.36000 ?  695  HIS AAZA NE2 1 
ATOM   874  N N   . TRP A 1 154 ? 50.77900 26.68800 89.38800  1.000 76.96000  ?  696  TRP AAZA N   1 
ATOM   875  C CA  . TRP A 1 154 ? 51.55200 27.64300 88.60700  1.000 77.15000  ?  696  TRP AAZA CA  1 
ATOM   876  C C   . TRP A 1 154 ? 52.57400 26.94200 87.72800  1.000 77.61000  ?  696  TRP AAZA C   1 
ATOM   877  O O   . TRP A 1 154 ? 52.55000 27.05800 86.49800  1.000 74.81000  ?  696  TRP AAZA O   1 
ATOM   878  C CB  . TRP A 1 154 ? 52.24200 28.61900 89.55800  1.000 73.77000  ?  696  TRP AAZA CB  1 
ATOM   879  C CG  . TRP A 1 154 ? 52.93300 29.74500 88.87600  1.000 73.71000  ?  696  TRP AAZA CG  1 
ATOM   880  C CD1 . TRP A 1 154 ? 53.12000 29.91300 87.53600  1.000 71.13000  ?  696  TRP AAZA CD1 1 
ATOM   881  C CD2 . TRP A 1 154 ? 53.50000 30.89100 89.50500  1.000 71.97000  ?  696  TRP AAZA CD2 1 
ATOM   882  N NE1 . TRP A 1 154 ? 53.79000 31.07500 87.30200  1.000 67.84000  ?  696  TRP AAZA NE1 1 
ATOM   883  C CE2 . TRP A 1 154 ? 54.03100 31.69700 88.49800  1.000 67.89000  ?  696  TRP AAZA CE2 1 
ATOM   884  C CE3 . TRP A 1 154 ? 53.62000 31.30800 90.83400  1.000 81.35000  ?  696  TRP AAZA CE3 1 
ATOM   885  C CZ2 . TRP A 1 154 ? 54.67400 32.89900 88.77400  1.000 71.96000  ?  696  TRP AAZA CZ2 1 
ATOM   886  C CZ3 . TRP A 1 154 ? 54.27000 32.51400 91.10500  1.000 78.89000  ?  696  TRP AAZA CZ3 1 
ATOM   887  C CH2 . TRP A 1 154 ? 54.78500 33.28800 90.08200  1.000 70.75000  ?  696  TRP AAZA CH2 1 
ATOM   888  N N   . VAL A 1 155 ? 53.47000 26.19100 88.35700  1.000 78.73000  ?  697  VAL AAZA N   1 
ATOM   889  C CA  . VAL A 1 155 ? 54.67700 25.70600 87.71400  1.000 78.61000  ?  697  VAL AAZA CA  1 
ATOM   890  C C   . VAL A 1 155 ? 54.28500 24.57200 86.78200  1.000 78.26000  ?  697  VAL AAZA C   1 
ATOM   891  O O   . VAL A 1 155 ? 55.13500 23.98400 86.11800  1.000 84.48000  ?  697  VAL AAZA O   1 
ATOM   892  C CB  . VAL A 1 155 ? 55.70800 25.23800 88.76200  1.000 78.58000  ?  697  VAL AAZA CB  1 
ATOM   893  C CG1 . VAL A 1 155 ? 55.27600 23.93700 89.39000  1.000 80.71000  ?  697  VAL AAZA CG1 1 
ATOM   894  C CG2 . VAL A 1 155 ? 57.10200 25.14600 88.18500  1.000 86.18000  ?  697  VAL AAZA CG2 1 
ATOM   895  N N   . GLU A 1 156 ? 53.00700 24.25400 86.71200  1.000 79.61000  ?  698  GLU AAZA N   1 
ATOM   896  C CA  . GLU A 1 156 ? 52.59200 23.07400 85.97100  1.000 88.00000  ?  698  GLU AAZA CA  1 
ATOM   897  C C   . GLU A 1 156 ? 51.58600 23.32800 84.86800  1.000 88.51000  ?  698  GLU AAZA C   1 
ATOM   898  O O   . GLU A 1 156 ? 51.44900 22.48300 83.98200  1.000 91.57000  ?  698  GLU AAZA O   1 
ATOM   899  C CB  . GLU A 1 156 ? 51.95300 22.03800 86.88800  1.000 97.02000  ?  698  GLU AAZA CB  1 
ATOM   900  C CG  . GLU A 1 156 ? 52.05100 20.66200 86.28100  1.000 107.75000 ?  698  GLU AAZA CG  1 
ATOM   901  C CD  . GLU A 1 156 ? 50.79900 19.85000 86.45900  1.000 110.12000 ?  698  GLU AAZA CD  1 
ATOM   902  O OE1 . GLU A 1 156 ? 50.19800 19.88700 87.56800  1.000 109.17000 ?  698  GLU AAZA OE1 1 
ATOM   903  O OE2 . GLU A 1 156 ? 50.45800 19.14900 85.47300  1.000 107.87000 ?  698  GLU AAZA OE2 1 
ATOM   904  N N   . HIS A 1 157 ? 50.83100 24.42100 84.92700  1.000 85.73000  ?  699  HIS AAZA N   1 
ATOM   905  C CA  . HIS A 1 157 ? 49.89500 24.75700 83.86800  1.000 86.97000  ?  699  HIS AAZA CA  1 
ATOM   906  C C   . HIS A 1 157 ? 50.21300 26.08100 83.19800  1.000 84.28000  ?  699  HIS AAZA C   1 
ATOM   907  O O   . HIS A 1 157 ? 49.55400 26.44000 82.21100  1.000 81.43000  ?  699  HIS AAZA O   1 
ATOM   908  C CB  . HIS A 1 157 ? 48.47900 24.78600 84.42800  1.000 85.20000  ?  699  HIS AAZA CB  1 
ATOM   909  C CG  . HIS A 1 157 ? 48.00600 23.44800 84.87700  1.000 89.39000  ?  699  HIS AAZA CG  1 
ATOM   910  N ND1 . HIS A 1 157 ? 47.75000 23.15800 86.19700  1.000 98.75000  ?  699  HIS AAZA ND1 1 
ATOM   911  C CD2 . HIS A 1 157 ? 47.78100 22.30800 84.18800  1.000 92.23000  ?  699  HIS AAZA CD2 1 
ATOM   912  C CE1 . HIS A 1 157 ? 47.36500 21.90000 86.30100  1.000 100.90000 ?  699  HIS AAZA CE1 1 
ATOM   913  N NE2 . HIS A 1 157 ? 47.37600 21.36200 85.09600  1.000 98.11000  ?  699  HIS AAZA NE2 1 
ATOM   914  N N   . HIS A 1 158 ? 51.21600 26.79400 83.69900  1.000 78.82000  ?  700  HIS AAZA N   1 
ATOM   915  C CA  . HIS A 1 158 ? 51.65400 28.07100 83.17600  1.000 73.01000  ?  700  HIS AAZA CA  1 
ATOM   916  C C   . HIS A 1 158 ? 53.15400 28.15400 83.21100  1.000 69.49000  ?  700  HIS AAZA C   1 
ATOM   917  O O   . HIS A 1 158 ? 53.72800 29.20500 83.49900  1.000 69.02000  ?  700  HIS AAZA O   1 
ATOM   918  C CB  . HIS A 1 158 ? 51.02800 29.20100 83.96300  1.000 74.06000  ?  700  HIS AAZA CB  1 
ATOM   919  C CG  . HIS A 1 158 ? 49.54400 29.11300 84.01000  1.000 73.92000  ?  700  HIS AAZA CG  1 
ATOM   920  N ND1 . HIS A 1 158 ? 48.87000 28.45300 85.01300  1.000 73.21000  ?  700  HIS AAZA ND1 1 
ATOM   921  C CD2 . HIS A 1 158 ? 48.60000 29.61600 83.18400  1.000 71.92000  ?  700  HIS AAZA CD2 1 
ATOM   922  C CE1 . HIS A 1 158 ? 47.57200 28.54300 84.79700  1.000 72.39000  ?  700  HIS AAZA CE1 1 
ATOM   923  N NE2 . HIS A 1 158 ? 47.38300 29.25000 83.69800  1.000 76.09000  ?  700  HIS AAZA NE2 1 
ATOM   924  N N   . PHE A 1 159 ? 53.81400 27.04300 82.89600  1.000 72.38000  ?  701  PHE AAZA N   1 
ATOM   925  C CA  . PHE A 1 159 ? 55.26500 26.99500 83.00200  1.000 74.05000  ?  701  PHE AAZA CA  1 
ATOM   926  C C   . PHE A 1 159 ? 55.96400 27.98300 82.08700  1.000 73.23000  ?  701  PHE AAZA C   1 
ATOM   927  O O   . PHE A 1 159 ? 57.13500 28.29100 82.33200  1.000 70.78000  ?  701  PHE AAZA O   1 
ATOM   928  C CB  . PHE A 1 159 ? 55.77400 25.59600 82.70200  1.000 79.91000  ?  701  PHE AAZA CB  1 
ATOM   929  C CG  . PHE A 1 159 ? 57.20600 25.39500 83.06900  1.000 82.13000  ?  701  PHE AAZA CG  1 
ATOM   930  C CD1 . PHE A 1 159 ? 57.61100 25.42500 84.38900  1.000 85.13000  ?  701  PHE AAZA CD1 1 
ATOM   931  C CD2 . PHE A 1 159 ? 58.14800 25.15800 82.10200  1.000 84.87000  ?  701  PHE AAZA CD2 1 
ATOM   932  C CE1 . PHE A 1 159 ? 58.94400 25.23100 84.72300  1.000 84.32000  ?  701  PHE AAZA CE1 1 
ATOM   933  C CE2 . PHE A 1 159 ? 59.47200 24.95000 82.44100  1.000 84.54000  ?  701  PHE AAZA CE2 1 
ATOM   934  C CZ  . PHE A 1 159 ? 59.86500 24.98200 83.74400  1.000 79.41000  ?  701  PHE AAZA CZ  1 
ATOM   935  N N   . TYR A 1 160 ? 55.27600 28.47900 81.04100  1.000 74.22000  ?  702  TYR AAZA N   1 
ATOM   936  C CA  . TYR A 1 160 ? 55.83800 29.49900 80.15900  1.000 67.21000  ?  702  TYR AAZA CA  1 
ATOM   937  C C   . TYR A 1 160 ? 56.36100 30.70700 80.92800  1.000 68.62000  ?  702  TYR AAZA C   1 
ATOM   938  O O   . TYR A 1 160 ? 57.24400 31.41300 80.42800  1.000 64.03000  ?  702  TYR AAZA O   1 
ATOM   939  C CB  . TYR A 1 160 ? 54.81100 29.97900 79.12900  1.000 63.70000  ?  702  TYR AAZA CB  1 
ATOM   940  C CG  . TYR A 1 160 ? 53.51400 30.63300 79.60200  1.000 62.37000  ?  702  TYR AAZA CG  1 
ATOM   941  C CD1 . TYR A 1 160 ? 53.40300 32.02600 79.74000  1.000 57.49000  ?  702  TYR AAZA CD1 1 
ATOM   942  C CD2 . TYR A 1 160 ? 52.37000 29.87000 79.79800  1.000 67.58000  ?  702  TYR AAZA CD2 1 
ATOM   943  C CE1 . TYR A 1 160 ? 52.19200 32.63200 80.12800  1.000 59.83000  ?  702  TYR AAZA CE1 1 
ATOM   944  C CE2 . TYR A 1 160 ? 51.15800 30.45300 80.19200  1.000 70.22000  ?  702  TYR AAZA CE2 1 
ATOM   945  C CZ  . TYR A 1 160 ? 51.06800 31.83000 80.36000  1.000 72.82000  ?  702  TYR AAZA CZ  1 
ATOM   946  O OH  . TYR A 1 160 ? 49.82700 32.35500 80.74100  1.000 75.98000  ?  702  TYR AAZA OH  1 
ATOM   947  N N   . ASP A 1 161 ? 55.82700 30.96300 82.12800  1.000 68.34000  ?  703  ASP AAZA N   1 
ATOM   948  C CA  . ASP A 1 161 ? 56.36600 32.01900 82.96900  1.000 65.62000  ?  703  ASP AAZA CA  1 
ATOM   949  C C   . ASP A 1 161 ? 57.82400 31.76500 83.29700  1.000 69.50000  ?  703  ASP AAZA C   1 
ATOM   950  O O   . ASP A 1 161 ? 58.61100 32.70800 83.41700  1.000 72.98000  ?  703  ASP AAZA O   1 
ATOM   951  C CB  . ASP A 1 161 ? 55.56600 32.13600 84.26300  1.000 67.82000  ?  703  ASP AAZA CB  1 
ATOM   952  C CG  . ASP A 1 161 ? 54.30400 32.96400 84.11200  1.000 71.69000  ?  703  ASP AAZA CG  1 
ATOM   953  O OD1 . ASP A 1 161 ? 54.24200 33.81700 83.19400  1.000 72.73000  ?  703  ASP AAZA OD1 1 
ATOM   954  O OD2 . ASP A 1 161 ? 53.40200 32.81500 84.96800  1.000 70.24000  ?  703  ASP AAZA OD2 1 
ATOM   955  N N   . PHE A 1 162 ? 58.20300 30.50700 83.45900  1.000 68.18000  ?  704  PHE AAZA N   1 
ATOM   956  C CA  . PHE A 1 162 ? 59.56200 30.18600 83.84800  1.000 68.50000  ?  704  PHE AAZA CA  1 
ATOM   957  C C   . PHE A 1 162 ? 60.45200 29.87900 82.66000  1.000 73.22000  ?  704  PHE AAZA C   1 
ATOM   958  O O   . PHE A 1 162 ? 61.67300 30.02500 82.77900  1.000 75.25000  ?  704  PHE AAZA O   1 
ATOM   959  C CB  . PHE A 1 162 ? 59.55500 29.02000 84.85400  1.000 72.60000  ?  704  PHE AAZA CB  1 
ATOM   960  C CG  . PHE A 1 162 ? 58.58700 29.22800 86.01300  1.000 76.18000  ?  704  PHE AAZA CG  1 
ATOM   961  C CD1 . PHE A 1 162 ? 58.95700 29.99500 87.12000  1.000 72.12000  ?  704  PHE AAZA CD1 1 
ATOM   962  C CD2 . PHE A 1 162 ? 57.30000 28.69300 85.97900  1.000 73.95000  ?  704  PHE AAZA CD2 1 
ATOM   963  C CE1 . PHE A 1 162 ? 58.08400 30.20100 88.16300  1.000 68.63000  ?  704  PHE AAZA CE1 1 
ATOM   964  C CE2 . PHE A 1 162 ? 56.42000 28.91000 87.02700  1.000 72.83000  ?  704  PHE AAZA CE2 1 
ATOM   965  C CZ  . PHE A 1 162 ? 56.81400 29.66600 88.11600  1.000 70.04000  ?  704  PHE AAZA CZ  1 
ATOM   966  N N   . GLU A 1 163 ? 59.87200 29.47800 81.51800  1.000 76.86000  ?  705  GLU AAZA N   1 
ATOM   967  C CA  . GLU A 1 163 ? 60.63800 29.38300 80.27500  1.000 70.43000  ?  705  GLU AAZA CA  1 
ATOM   968  C C   . GLU A 1 163 ? 61.24100 30.74200 79.92500  1.000 73.08000  ?  705  GLU AAZA C   1 
ATOM   969  O O   . GLU A 1 163 ? 62.42000 30.83800 79.55300  1.000 74.79000  ?  705  GLU AAZA O   1 
ATOM   970  C CB  . GLU A 1 163 ? 59.74300 28.90700 79.12500  1.000 68.88000  ?  705  GLU AAZA CB  1 
ATOM   971  C CG  . GLU A 1 163 ? 59.10300 27.52800 79.26300  1.000 79.72000  ?  705  GLU AAZA CG  1 
ATOM   972  C CD  . GLU A 1 163 ? 58.39600 27.03700 77.97100  1.000 90.73000  ?  705  GLU AAZA CD  1 
ATOM   973  O OE1 . GLU A 1 163 ? 59.10600 26.57500 77.05300  1.000 106.28000 ?  705  GLU AAZA OE1 1 
ATOM   974  O OE2 . GLU A 1 163 ? 57.14300 27.15900 77.84500  1.000 81.81000  ?  705  GLU AAZA OE2 1 
ATOM   975  N N   . ARG A 1 164 ? 60.45000 31.80800 80.06200  1.000 67.65000  ?  706  ARG AAZA N   1 
ATOM   976  C CA  . ARG A 1 164 ? 60.83700 33.13800 79.62100  1.000 67.70000  ?  706  ARG AAZA CA  1 
ATOM   977  C C   . ARG A 1 164 ? 61.60800 33.91700 80.65900  1.000 74.18000  ?  706  ARG AAZA C   1 
ATOM   978  O O   . ARG A 1 164 ? 61.87700 35.10200 80.43800  1.000 78.11000  ?  706  ARG AAZA O   1 
ATOM   979  C CB  . ARG A 1 164 ? 59.60700 33.94700 79.23100  1.000 65.87000  ?  706  ARG AAZA CB  1 
ATOM   980  C CG  . ARG A 1 164 ? 58.73100 33.26300 78.23900  1.000 68.18000  ?  706  ARG AAZA CG  1 
ATOM   981  C CD  . ARG A 1 164 ? 57.55500 34.11600 77.89300  1.000 62.54000  ?  706  ARG AAZA CD  1 
ATOM   982  N NE  . ARG A 1 164 ? 56.66300 33.39700 76.99900  1.000 66.61000  ?  706  ARG AAZA NE  1 
ATOM   983  C CZ  . ARG A 1 164 ? 55.41700 33.77100 76.77000  1.000 67.92000  ?  706  ARG AAZA CZ  1 
ATOM   984  N NH1 . ARG A 1 164 ? 54.90300 34.83000 77.38400  1.000 62.20000  ?  706  ARG AAZA NH1 1 
ATOM   985  N NH2 . ARG A 1 164 ? 54.67000 33.06300 75.91600  1.000 66.46000  ?  706  ARG AAZA NH2 1 
ATOM   986  N N   . ASP A 1 165 ? 61.94000 33.30000 81.79600  1.000 79.60000  ?  707  ASP AAZA N   1 
ATOM   987  C CA  . ASP A 1 165 ? 62.57000 34.02400 82.90700  1.000 76.97000  ?  707  ASP AAZA CA  1 
ATOM   988  C C   . ASP A 1 165 ? 63.26800 32.99000 83.79100  1.000 83.06000  ?  707  ASP AAZA C   1 
ATOM   989  O O   . ASP A 1 165 ? 62.61100 32.34300 84.61000  1.000 86.51000  ?  707  ASP AAZA O   1 
ATOM   990  C CB  . ASP A 1 165 ? 61.54600 34.82500 83.69700  1.000 69.77000  ?  707  ASP AAZA CB  1 
ATOM   991  C CG  . ASP A 1 165 ? 62.17900 35.92000 84.52000  1.000 76.99000  ?  707  ASP AAZA CG  1 
ATOM   992  O OD1 . ASP A 1 165 ? 63.40600 35.84600 84.75000  1.000 78.92000  ?  707  ASP AAZA OD1 1 
ATOM   993  O OD2 . ASP A 1 165 ? 61.45800 36.86000 84.94200  1.000 81.66000  ?  707  ASP AAZA OD2 1 
ATOM   994  N N   . ALA A 1 166 ? 64.59000 32.84400 83.62000  1.000 84.48000  ?  708  ALA AAZA N   1 
ATOM   995  C CA  . ALA A 1 166 ? 65.32400 31.86900 84.42600  1.000 82.66000  ?  708  ALA AAZA CA  1 
ATOM   996  C C   . ALA A 1 166 ? 65.35100 32.27800 85.89500  1.000 81.45000  ?  708  ALA AAZA C   1 
ATOM   997  O O   . ALA A 1 166 ? 65.21900 31.42800 86.77500  1.000 84.16000  ?  708  ALA AAZA O   1 
ATOM   998  C CB  . ALA A 1 166 ? 66.74600 31.68300 83.89200  1.000 78.20000  ?  708  ALA AAZA CB  1 
ATOM   999  N N   . TYR A 1 167 ? 65.50000 33.57300 86.17800  1.000 80.27000  ?  709  TYR AAZA N   1 
ATOM   1000 C CA  . TYR A 1 167 ? 65.57400 34.01800 87.56300  1.000 81.03000  ?  709  TYR AAZA CA  1 
ATOM   1001 C C   . TYR A 1 167 ? 64.26900 33.75200 88.30500  1.000 87.48000  ?  709  TYR AAZA C   1 
ATOM   1002 O O   . TYR A 1 167 ? 64.28900 33.34900 89.47500  1.000 88.87000  ?  709  TYR AAZA O   1 
ATOM   1003 C CB  . TYR A 1 167 ? 65.95500 35.49500 87.62100  1.000 77.86000  ?  709  TYR AAZA CB  1 
ATOM   1004 C CG  . TYR A 1 167 ? 66.00700 36.06200 89.01600  1.000 84.98000  ?  709  TYR AAZA CG  1 
ATOM   1005 C CD1 . TYR A 1 167 ? 66.71000 35.41400 90.04400  1.000 89.01000  ?  709  TYR AAZA CD1 1 
ATOM   1006 C CD2 . TYR A 1 167 ? 65.39500 37.26400 89.30900  1.000 87.73000  ?  709  TYR AAZA CD2 1 
ATOM   1007 C CE1 . TYR A 1 167 ? 66.76100 35.95000 91.34100  1.000 83.56000  ?  709  TYR AAZA CE1 1 
ATOM   1008 C CE2 . TYR A 1 167 ? 65.44400 37.80600 90.59700  1.000 95.01000  ?  709  TYR AAZA CE2 1 
ATOM   1009 C CZ  . TYR A 1 167 ? 66.12700 37.14800 91.59900  1.000 88.71000  ?  709  TYR AAZA CZ  1 
ATOM   1010 O OH  . TYR A 1 167 ? 66.15100 37.72100 92.84500  1.000 95.82000  ?  709  TYR AAZA OH  1 
ATOM   1011 N N   . LEU A 1 168 ? 63.12200 33.95200 87.64800  1.000 83.93000  ?  710  LEU AAZA N   1 
ATOM   1012 C CA  . LEU A 1 168 ? 61.87200 33.55200 88.28300  1.000 80.74000  ?  710  LEU AAZA CA  1 
ATOM   1013 C C   . LEU A 1 168 ? 61.92200 32.08200 88.67800  1.000 84.85000  ?  710  LEU AAZA C   1 
ATOM   1014 O O   . LEU A 1 168 ? 61.54600 31.72800 89.79900  1.000 86.90000  ?  710  LEU AAZA O   1 
ATOM   1015 C CB  . LEU A 1 168 ? 60.67700 33.81200 87.37200  1.000 74.78000  ?  710  LEU AAZA CB  1 
ATOM   1016 C CG  . LEU A 1 168 ? 59.30600 33.62000 88.03400  1.000 71.87000  ?  710  LEU AAZA CG  1 
ATOM   1017 C CD1 . LEU A 1 168 ? 58.94600 34.82000 88.89600  1.000 68.28000  ?  710  LEU AAZA CD1 1 
ATOM   1018 C CD2 . LEU A 1 168 ? 58.23600 33.36400 87.01000  1.000 70.55000  ?  710  LEU AAZA CD2 1 
ATOM   1019 N N   . LEU A 1 169 ? 62.40200 31.20600 87.78700  1.000 81.54000  ?  711  LEU AAZA N   1 
ATOM   1020 C CA  . LEU A 1 169 ? 62.53600 29.80600 88.17800  1.000 79.15000  ?  711  LEU AAZA CA  1 
ATOM   1021 C C   . LEU A 1 169 ? 63.53800 29.63100 89.31000  1.000 83.55000  ?  711  LEU AAZA C   1 
ATOM   1022 O O   . LEU A 1 169 ? 63.37100 28.75400 90.15500  1.000 91.71000  ?  711  LEU AAZA O   1 
ATOM   1023 C CB  . LEU A 1 169 ? 62.93700 28.94200 86.98900  1.000 73.74000  ?  711  LEU AAZA CB  1 
ATOM   1024 C CG  . LEU A 1 169 ? 62.88500 27.44900 87.31000  1.000 77.82000  ?  711  LEU AAZA CG  1 
ATOM   1025 C CD1 . LEU A 1 169 ? 61.62800 27.13600 88.06900  1.000 87.27000  ?  711  LEU AAZA CD1 1 
ATOM   1026 C CD2 . LEU A 1 169 ? 62.87000 26.64400 86.05900  1.000 84.92000  ?  711  LEU AAZA CD2 1 
ATOM   1027 N N   . GLN A 1 170 ? 64.57600 30.45500 89.35200  1.000 81.93000  ?  712  GLN AAZA N   1 
ATOM   1028 C CA  . GLN A 1 170 ? 65.58900 30.32700 90.38800  1.000 82.70000  ?  712  GLN AAZA CA  1 
ATOM   1029 C C   . GLN A 1 170 ? 64.96900 30.55900 91.75600  1.000 86.71000  ?  712  GLN AAZA C   1 
ATOM   1030 O O   . GLN A 1 170 ? 64.98600 29.68400 92.62700  1.000 85.38000  ?  712  GLN AAZA O   1 
ATOM   1031 C CB  . GLN A 1 170 ? 66.69000 31.34400 90.10500  1.000 89.79000  ?  712  GLN AAZA CB  1 
ATOM   1032 C CG  . GLN A 1 170 ? 68.04600 31.04900 90.66200  1.000 99.50000  ?  712  GLN AAZA CG  1 
ATOM   1033 C CD  . GLN A 1 170 ? 69.10900 31.81500 89.89600  1.000 110.98000 ?  712  GLN AAZA CD  1 
ATOM   1034 O OE1 . GLN A 1 170 ? 69.69400 31.29900 88.92500  1.000 116.09000 ?  712  GLN AAZA OE1 1 
ATOM   1035 N NE2 . GLN A 1 170 ? 69.35600 33.05700 90.30900  1.000 107.14000 ?  712  GLN AAZA NE2 1 
ATOM   1036 N N   . ARG A 1 171 ? 64.37700 31.73900 91.93700  1.000 87.64000  ?  713  ARG AAZA N   1 
ATOM   1037 C CA  . ARG A 1 171 ? 63.67500 32.07900 93.16300  1.000 80.91000  ?  713  ARG AAZA CA  1 
ATOM   1038 C C   . ARG A 1 171 ? 62.72400 30.96600 93.59100  1.000 83.63000  ?  713  ARG AAZA C   1 
ATOM   1039 O O   . ARG A 1 171 ? 62.60900 30.67500 94.78100  1.000 95.57000  ?  713  ARG AAZA O   1 
ATOM   1040 C CB  . ARG A 1 171 ? 62.90900 33.38200 92.95800  1.000 76.90000  ?  713  ARG AAZA CB  1 
ATOM   1041 C CG  . ARG A 1 171 ? 63.74000 34.63700 92.92100  1.000 81.48000  ?  713  ARG AAZA CG  1 
ATOM   1042 C CD  . ARG A 1 171 ? 62.86000 35.85600 92.67000  1.000 83.02000  ?  713  ARG AAZA CD  1 
ATOM   1043 N NE  . ARG A 1 171 ? 61.81100 35.96800 93.67800  1.000 88.67000  ?  713  ARG AAZA NE  1 
ATOM   1044 C CZ  . ARG A 1 171 ? 61.09400 37.06200 93.90400  1.000 90.62000  ?  713  ARG AAZA CZ  1 
ATOM   1045 N NH1 . ARG A 1 171 ? 61.24200 38.15000 93.16100  1.000 93.15000  ?  713  ARG AAZA NH1 1 
ATOM   1046 N NH2 . ARG A 1 171 ? 60.20300 37.06700 94.90100  1.000 83.66000  ?  713  ARG AAZA NH2 1 
ATOM   1047 N N   . MET A 1 172 ? 62.04000 30.31900 92.64600  1.000 79.40000  ?  714  MET AAZA N   1 
ATOM   1048 C CA  . MET A 1 172 ? 61.08800 29.28300 93.03200  1.000 79.59000  ?  714  MET AAZA CA  1 
ATOM   1049 C C   . MET A 1 172 ? 61.79500 28.07900 93.62500  1.000 88.68000  ?  714  MET AAZA C   1 
ATOM   1050 O O   . MET A 1 172 ? 61.31300 27.49100 94.60000  1.000 99.18000  ?  714  MET AAZA O   1 
ATOM   1051 C CB  . MET A 1 172 ? 60.25000 28.82100 91.84800  1.000 83.67000  ?  714  MET AAZA CB  1 
ATOM   1052 C CG  . MET A 1 172 ? 59.26200 27.69600 92.19100  1.000 79.94000  ?  714  MET AAZA CG  1 
ATOM   1053 S SD  . MET A 1 172 ? 57.72600 28.36000 92.87700  1.000 75.99000  ?  714  MET AAZA SD  1 
ATOM   1054 C CE  . MET A 1 172 ? 56.54000 27.68600 91.71600  1.000 82.18000  ?  714  MET AAZA CE  1 
ATOM   1055 N N   . GLU A 1 173 ? 62.92100 27.67100 93.04700  1.000 86.50000  ?  715  GLU AAZA N   1 
ATOM   1056 C CA  . GLU A 1 173 ? 63.62200 26.52700 93.61400  1.000 89.84000  ?  715  GLU AAZA CA  1 
ATOM   1057 C C   . GLU A 1 173 ? 64.28200 26.89600 94.93700  1.000 94.81000  ?  715  GLU AAZA C   1 
ATOM   1058 O O   . GLU A 1 173 ? 64.25400 26.10300 95.88300  1.000 99.90000  ?  715  GLU AAZA O   1 
ATOM   1059 C CB  . GLU A 1 173 ? 64.61200 25.97300 92.60100  1.000 84.27000  ?  715  GLU AAZA CB  1 
ATOM   1060 C CG  . GLU A 1 173 ? 63.94600 25.87600 91.25300  1.000 91.40000  ?  715  GLU AAZA CG  1 
ATOM   1061 C CD  . GLU A 1 173 ? 64.65200 24.96100 90.26400  1.000 106.27000 ?  715  GLU AAZA CD  1 
ATOM   1062 O OE1 . GLU A 1 173 ? 65.68400 25.36300 89.66300  1.000 108.28000 ?  715  GLU AAZA OE1 1 
ATOM   1063 O OE2 . GLU A 1 173 ? 64.14500 23.82900 90.07500  1.000 109.43000 ?  715  GLU AAZA OE2 1 
ATOM   1064 N N   . GLU A 1 174 ? 64.84900 28.10300 95.03300  1.000 91.71000  ?  716  GLU AAZA N   1 
ATOM   1065 C CA  . GLU A 1 174 ? 65.20800 28.66300 96.33200  1.000 87.78000  ?  716  GLU AAZA CA  1 
ATOM   1066 C C   . GLU A 1 174 ? 64.03600 28.54200 97.29600  1.000 95.31000  ?  716  GLU AAZA C   1 
ATOM   1067 O O   . GLU A 1 174 ? 64.12200 27.84100 98.30900  1.000 101.81000 ?  716  GLU AAZA O   1 
ATOM   1068 C CB  . GLU A 1 174 ? 65.64000 30.12600 96.17600  1.000 87.96000  ?  716  GLU AAZA CB  1 
ATOM   1069 C CG  . GLU A 1 174 ? 67.08800 30.46000 96.55500  1.000 95.65000  ?  716  GLU AAZA CG  1 
ATOM   1070 C CD  . GLU A 1 174 ? 67.41900 31.96900 96.39900  1.000 112.32000 ?  716  GLU AAZA CD  1 
ATOM   1071 O OE1 . GLU A 1 174 ? 66.47800 32.79900 96.43200  1.000 113.38000 ?  716  GLU AAZA OE1 1 
ATOM   1072 O OE2 . GLU A 1 174 ? 68.61700 32.33300 96.24700  1.000 111.43000 ?  716  GLU AAZA OE2 1 
ATOM   1073 N N   . PHE A 1 175 ? 62.90800 29.18200 96.96600  1.000 94.37000  ?  717  PHE AAZA N   1 
ATOM   1074 C CA  . PHE A 1 175 ? 61.78300 29.21600 97.89700  1.000 95.94000  ?  717  PHE AAZA CA  1 
ATOM   1075 C C   . PHE A 1 175 ? 61.33800 27.81600 98.28800  1.000 97.79000  ?  717  PHE AAZA C   1 
ATOM   1076 O O   . PHE A 1 175 ? 61.07300 27.55000 99.46100  1.000 104.74000 ?  717  PHE AAZA O   1 
ATOM   1077 C CB  . PHE A 1 175 ? 60.59400 29.97700 97.32000  1.000 92.34000  ?  717  PHE AAZA CB  1 
ATOM   1078 C CG  . PHE A 1 175 ? 59.29200 29.61400 97.97800  1.000 100.69000 ?  717  PHE AAZA CG  1 
ATOM   1079 C CD1 . PHE A 1 175 ? 58.95800 30.14000 99.22700  1.000 93.72000  ?  717  PHE AAZA CD1 1 
ATOM   1080 C CD2 . PHE A 1 175 ? 58.42200 28.69600 97.38300  1.000 100.41000 ?  717  PHE AAZA CD2 1 
ATOM   1081 C CE1 . PHE A 1 175 ? 57.76400 29.79200 99.85400  1.000 87.05000  ?  717  PHE AAZA CE1 1 
ATOM   1082 C CE2 . PHE A 1 175 ? 57.22900 28.33100 98.01100  1.000 98.69000  ?  717  PHE AAZA CE2 1 
ATOM   1083 C CZ  . PHE A 1 175 ? 56.90200 28.88600 99.25000  1.000 90.59000  ?  717  PHE AAZA CZ  1 
ATOM   1084 N N   . ILE A 1 176 ? 61.22600 26.90300 97.32800  1.000 92.75000  ?  718  ILE AAZA N   1 
ATOM   1085 C CA  . ILE A 1 176 ? 60.82700 25.55800 97.71500  1.000 101.18000 ?  718  ILE AAZA CA  1 
ATOM   1086 C C   . ILE A 1 176 ? 61.93400 24.78200 98.41600  1.000 108.61000 ?  718  ILE AAZA C   1 
ATOM   1087 O O   . ILE A 1 176 ? 61.64200 23.78800 99.09700  1.000 113.91000 ?  718  ILE AAZA O   1 
ATOM   1088 C CB  . ILE A 1 176 ? 60.20800 24.88300 96.48000  1.000 99.21000  ?  718  ILE AAZA CB  1 
ATOM   1089 C CG1 . ILE A 1 176 ? 58.86600 25.55000 96.25300  1.000 98.24000  ?  718  ILE AAZA CG1 1 
ATOM   1090 C CG2 . ILE A 1 176 ? 60.08500 23.37900 96.60600  1.000 104.80000 ?  718  ILE AAZA CG2 1 
ATOM   1091 C CD1 . ILE A 1 176 ? 57.93500 24.70800 95.51400  1.000 102.20000 ?  718  ILE AAZA CD1 1 
ATOM   1092 N N   . GLY A 1 177 ? 63.13300 25.34900 98.43900  1.000 106.03000 ?  719  GLY AAZA N   1 
ATOM   1093 C CA  . GLY A 1 177 ? 64.16900 24.71400 99.26900  1.000 109.37000 ?  719  GLY AAZA CA  1 
ATOM   1094 C C   . GLY A 1 177 ? 63.87000 25.04700 100.72000 1.000 112.65000 ?  719  GLY AAZA C   1 
ATOM   1095 O O   . GLY A 1 177 ? 63.81100 24.11500 101.53800 1.000 114.93000 ?  719  GLY AAZA O   1 
ATOM   1096 N N   . THR A 1 178 ? 63.63300 26.32900 101.01200 1.000 108.49000 ?  720  THR AAZA N   1 
ATOM   1097 C CA  . THR A 1 178 ? 63.33600 26.77600 102.39700 1.000 111.76000 ?  720  THR AAZA CA  1 
ATOM   1098 C C   . THR A 1 178 ? 62.16700 25.97300 102.96600 1.000 117.26000 ?  720  THR AAZA C   1 
ATOM   1099 O O   . THR A 1 178 ? 62.03000 25.92500 104.20000 1.000 123.78000 ?  720  THR AAZA O   1 
ATOM   1100 C CB  . THR A 1 178 ? 62.98300 28.26500 102.43000 1.000 112.03000 ?  720  THR AAZA CB  1 
ATOM   1101 O OG1 . THR A 1 178 ? 61.66400 28.40700 101.90500 1.000 131.25000 ?  720  THR AAZA OG1 1 
ATOM   1102 C CG2 . THR A 1 178 ? 63.95000 29.11600 101.63800 1.000 103.70000 ?  720  THR AAZA CG2 1 
ATOM   1103 N N   . VAL A 1 179 ? 61.35000 25.38600 102.09500 1.000 116.50000 ?  721  VAL AAZA N   1 
ATOM   1104 C CA  . VAL A 1 179 ? 60.14800 24.65400 102.58000 1.000 124.30000 ?  721  VAL AAZA CA  1 
ATOM   1105 C C   . VAL A 1 179 ? 60.62300 23.43900 103.37100 1.000 139.62000 ?  721  VAL AAZA C   1 
ATOM   1106 O O   . VAL A 1 179 ? 61.30600 22.58500 102.78300 1.000 143.03000 ?  721  VAL AAZA O   1 
ATOM   1107 C CB  . VAL A 1 179 ? 59.21200 24.23200 101.43400 1.000 124.74000 ?  721  VAL AAZA CB  1 
ATOM   1108 C CG1 . VAL A 1 179 ? 57.97200 23.53400 101.97000 1.000 125.21000 ?  721  VAL AAZA CG1 1 
ATOM   1109 C CG2 . VAL A 1 179 ? 58.82000 25.41700 100.56700 1.000 119.76000 ?  721  VAL AAZA CG2 1 
ATOM   1110 N N   . ARG A 1 180 ? 60.27100 23.38100 104.65300 1.000 142.57000 ?  722  ARG AAZA N   1 
ATOM   1111 C CA  . ARG A 1 180 ? 60.62700 22.21100 105.49600 1.000 144.04000 ?  722  ARG AAZA CA  1 
ATOM   1112 C C   . ARG A 1 180 ? 59.39000 21.84500 106.31700 1.000 141.53000 ?  722  ARG AAZA C   1 
ATOM   1113 O O   . ARG A 1 180 ? 58.41200 22.61400 106.27500 1.000 138.40000 ?  722  ARG AAZA O   1 
ATOM   1114 C CB  . ARG A 1 180 ? 61.84000 22.53100 106.37200 1.000 140.96000 ?  722  ARG AAZA CB  1 
ATOM   1115 C CG  . ARG A 1 180 ? 63.09700 22.86400 105.58200 1.000 138.24000 ?  722  ARG AAZA CG  1 
ATOM   1116 C CD  . ARG A 1 180 ? 64.21300 23.39700 106.45900 1.000 138.44000 ?  722  ARG AAZA CD  1 
ATOM   1117 N NE  . ARG A 1 180 ? 64.52300 22.48700 107.55100 1.000 153.19000 ?  722  ARG AAZA NE  1 
ATOM   1118 C CZ  . ARG A 1 180 ? 65.46500 22.70000 108.46200 1.000 152.93000 ?  722  ARG AAZA CZ  1 
ATOM   1119 N NH1 . ARG A 1 180 ? 66.28200 23.73000 108.34100 1.000 150.19000 ?  722  ARG AAZA NH1 1 
ATOM   1120 N NH2 . ARG A 1 180 ? 65.58700 21.87800 109.49000 1.000 140.15000 ?  722  ARG AAZA NH2 1 
ATOM   1121 N N   . GLY A 1 181 ? 59.43200 20.72500 107.03500 1.000 141.26000 ?  723  GLY AAZA N   1 
ATOM   1122 C CA  . GLY A 1 181 ? 58.23200 20.26800 107.75900 1.000 143.62000 ?  723  GLY AAZA CA  1 
ATOM   1123 C C   . GLY A 1 181 ? 57.64600 19.08400 107.02500 1.000 135.90000 ?  723  GLY AAZA C   1 
ATOM   1124 O O   . GLY A 1 181 ? 57.24300 19.25700 105.86200 1.000 135.56000 ?  723  GLY AAZA O   1 
ATOM   1125 N N   . LYS A 1 182 ? 57.60400 17.92000 107.66800 1.000 133.98000 ?  724  LYS AAZA N   1 
ATOM   1126 C CA  . LYS A 1 182 ? 57.17300 16.75100 106.91800 1.000 134.65000 ?  724  LYS AAZA CA  1 
ATOM   1127 C C   . LYS A 1 182 ? 55.72500 16.83200 106.44200 1.000 132.89000 ?  724  LYS AAZA C   1 
ATOM   1128 O O   . LYS A 1 182 ? 55.25700 15.89500 105.78100 1.000 128.08000 ?  724  LYS AAZA O   1 
ATOM   1129 C CB  . LYS A 1 182 ? 57.38500 15.49700 107.76800 1.000 140.88000 ?  724  LYS AAZA CB  1 
ATOM   1130 C CG  . LYS A 1 182 ? 58.82300 15.34300 108.28500 1.000 144.67000 ?  724  LYS AAZA CG  1 
ATOM   1131 C CD  . LYS A 1 182 ? 59.86700 15.80100 107.26600 1.000 141.75000 ?  724  LYS AAZA CD  1 
ATOM   1132 C CE  . LYS A 1 182 ? 61.28400 15.76100 107.84100 1.000 145.51000 ?  724  LYS AAZA CE  1 
ATOM   1133 N NZ  . LYS A 1 182 ? 62.03600 14.53300 107.43900 1.000 143.80000 ?  724  LYS AAZA NZ  1 
ATOM   1134 N N   . ALA A 1 183 ? 55.04400 17.93800 106.72900 1.000 132.61000 ?  725  ALA AAZA N   1 
ATOM   1135 C CA  . ALA A 1 183 ? 53.66600 18.09900 106.21400 1.000 135.76000 ?  725  ALA AAZA CA  1 
ATOM   1136 C C   . ALA A 1 183 ? 53.72200 18.45300 104.72700 1.000 137.04000 ?  725  ALA AAZA C   1 
ATOM   1137 O O   . ALA A 1 183 ? 52.84300 17.99500 103.97600 1.000 131.35000 ?  725  ALA AAZA O   1 
ATOM   1138 C CB  . ALA A 1 183 ? 52.95300 19.16600 106.99900 1.000 125.40000 ?  725  ALA AAZA CB  1 
ATOM   1139 N N   . MET A 1 184 ? 54.72700 19.23000 104.32400 1.000 131.78000 ?  726  MET AAZA N   1 
ATOM   1140 C CA  . MET A 1 184 ? 54.81300 19.68900 102.91800 1.000 124.63000 ?  726  MET AAZA CA  1 
ATOM   1141 C C   . MET A 1 184 ? 56.05400 19.08800 102.26300 1.000 126.26000 ?  726  MET AAZA C   1 
ATOM   1142 O O   . MET A 1 184 ? 56.19200 19.22700 101.03600 1.000 127.82000 ?  726  MET AAZA O   1 
ATOM   1143 C CB  . MET A 1 184 ? 54.95100 21.21000 102.88700 1.000 126.08000 ?  726  MET AAZA CB  1 
ATOM   1144 C CG  . MET A 1 184 ? 53.64600 21.94800 103.06300 1.000 126.80000 ?  726  MET AAZA CG  1 
ATOM   1145 S SD  . MET A 1 184 ? 53.35000 22.35200 104.79600 1.000 135.37000 ?  726  MET AAZA SD  1 
ATOM   1146 C CE  . MET A 1 184 ? 54.39200 23.79900 104.97000 1.000 112.56000 ?  726  MET AAZA CE  1 
ATOM   1147 N N   . LYS A 1 185 ? 56.93100 18.47100 103.05300 1.000 129.21000 ?  727  LYS AAZA N   1 
ATOM   1148 C CA  . LYS A 1 185 ? 58.18900 17.96700 102.49900 1.000 130.92000 ?  727  LYS AAZA CA  1 
ATOM   1149 C C   . LYS A 1 185 ? 57.75900 16.90400 101.47900 1.000 127.30000 ?  727  LYS AAZA C   1 
ATOM   1150 O O   . LYS A 1 185 ? 58.58100 16.13600 100.96500 1.000 128.94000 ?  727  LYS AAZA O   1 
ATOM   1151 C CB  . LYS A 1 185 ? 59.17700 17.47400 103.56800 1.000 134.62000 ?  727  LYS AAZA CB  1 
ATOM   1152 C CG  . LYS A 1 185 ? 60.61600 17.30700 103.08600 1.000 130.99000 ?  727  LYS AAZA CG  1 
ATOM   1153 C CD  . LYS A 1 185 ? 61.56500 16.97900 104.22300 1.000 136.85000 ?  727  LYS AAZA CD  1 
ATOM   1154 C CE  . LYS A 1 185 ? 61.67900 15.45300 104.39300 1.000 145.02000 ?  727  LYS AAZA CE  1 
ATOM   1155 N NZ  . LYS A 1 185 ? 62.64600 14.76300 103.48100 1.000 149.36000 ?  727  LYS AAZA NZ  1 
ATOM   1156 N N   . LYS A 1 186 ? 56.45900 16.86800 101.18200 1.000 123.34000 ?  728  LYS AAZA N   1 
ATOM   1157 C CA  . LYS A 1 186 ? 55.84200 15.98300 100.20700 1.000 124.54000 ?  728  LYS AAZA CA  1 
ATOM   1158 C C   . LYS A 1 186 ? 55.10400 16.73700 99.10600  1.000 122.47000 ?  728  LYS AAZA C   1 
ATOM   1159 O O   . LYS A 1 186 ? 54.91300 16.20700 98.00500  1.000 114.57000 ?  728  LYS AAZA O   1 
ATOM   1160 C CB  . LYS A 1 186 ? 54.89300 15.07000 100.98300 1.000 130.70000 ?  728  LYS AAZA CB  1 
ATOM   1161 C CG  . LYS A 1 186 ? 53.84800 15.78700 101.84300 1.000 129.93000 ?  728  LYS AAZA CG  1 
ATOM   1162 C CD  . LYS A 1 186 ? 53.52100 14.96400 103.10700 1.000 133.69000 ?  728  LYS AAZA CD  1 
ATOM   1163 C CE  . LYS A 1 186 ? 52.98900 13.56100 102.74100 1.000 132.76000 ?  728  LYS AAZA CE  1 
ATOM   1164 N NZ  . LYS A 1 186 ? 52.15700 12.87600 103.78400 1.000 120.48000 ?  728  LYS AAZA NZ  1 
ATOM   1165 N N   . TRP A 1 187 ? 54.66400 17.96900 99.40400  1.000 125.58000 ?  729  TRP AAZA N   1 
ATOM   1166 C CA  . TRP A 1 187 ? 54.30500 18.89600 98.33100  1.000 120.06000 ?  729  TRP AAZA CA  1 
ATOM   1167 C C   . TRP A 1 187 ? 55.54100 19.31100 97.55200  1.000 115.59000 ?  729  TRP AAZA C   1 
ATOM   1168 O O   . TRP A 1 187 ? 55.50400 19.39100 96.31800  1.000 112.14000 ?  729  TRP AAZA O   1 
ATOM   1169 C CB  . TRP A 1 187 ? 53.60500 20.14900 98.87100  1.000 115.41000 ?  729  TRP AAZA CB  1 
ATOM   1170 C CG  . TRP A 1 187 ? 52.13500 20.00900 99.14100  1.000 118.37000 ?  729  TRP AAZA CG  1 
ATOM   1171 C CD1 . TRP A 1 187 ? 51.54600 19.70600 100.33800 1.000 123.20000 ?  729  TRP AAZA CD1 1 
ATOM   1172 C CD2 . TRP A 1 187 ? 51.06400 20.14800 98.19400  1.000 112.98000 ?  729  TRP AAZA CD2 1 
ATOM   1173 N NE1 . TRP A 1 187 ? 50.17600 19.66600 100.19800 1.000 121.58000 ?  729  TRP AAZA NE1 1 
ATOM   1174 C CE2 . TRP A 1 187 ? 49.85500 19.92800 98.89200  1.000 117.63000 ?  729  TRP AAZA CE2 1 
ATOM   1175 C CE3 . TRP A 1 187 ? 51.00900 20.43700 96.82800  1.000 110.92000 ?  729  TRP AAZA CE3 1 
ATOM   1176 C CZ2 . TRP A 1 187 ? 48.60600 19.99200 98.26800  1.000 116.51000 ?  729  TRP AAZA CZ2 1 
ATOM   1177 C CZ3 . TRP A 1 187 ? 49.76500 20.49700 96.20800  1.000 110.27000 ?  729  TRP AAZA CZ3 1 
ATOM   1178 C CH2 . TRP A 1 187 ? 48.58300 20.27400 96.92700  1.000 114.58000 ?  729  TRP AAZA CH2 1 
ATOM   1179 N N   . VAL A 1 188 ? 56.64600 19.58200 98.25500  1.000 114.46000 ?  730  VAL AAZA N   1 
ATOM   1180 C CA  . VAL A 1 188 ? 57.86300 19.97200 97.56400  1.000 112.56000 ?  730  VAL AAZA CA  1 
ATOM   1181 C C   . VAL A 1 188 ? 58.42700 18.80500 96.77500  1.000 110.51000 ?  730  VAL AAZA C   1 
ATOM   1182 O O   . VAL A 1 188 ? 59.14500 19.01700 95.79800  1.000 114.04000 ?  730  VAL AAZA O   1 
ATOM   1183 C CB  . VAL A 1 188 ? 58.92300 20.52800 98.53400  1.000 111.12000 ?  730  VAL AAZA CB  1 
ATOM   1184 C CG1 . VAL A 1 188 ? 58.35900 21.69900 99.30500  1.000 111.04000 ?  730  VAL AAZA CG1 1 
ATOM   1185 C CG2 . VAL A 1 188 ? 59.45700 19.45400 99.43600  1.000 115.83000 ?  730  VAL AAZA CG2 1 
ATOM   1186 N N   . GLU A 1 189 ? 58.12300 17.57000 97.16500  1.000 114.52000 ?  731  GLU AAZA N   1 
ATOM   1187 C CA  . GLU A 1 189 ? 58.50900 16.43900 96.32800  1.000 117.81000 ?  731  GLU AAZA CA  1 
ATOM   1188 C C   . GLU A 1 189 ? 57.72400 16.43600 95.02300  1.000 110.50000 ?  731  GLU AAZA C   1 
ATOM   1189 O O   . GLU A 1 189 ? 58.20500 15.92500 94.00600  1.000 107.99000 ?  731  GLU AAZA O   1 
ATOM   1190 C CB  . GLU A 1 189 ? 58.29500 15.11800 97.08100  1.000 131.32000 ?  731  GLU AAZA CB  1 
ATOM   1191 C CG  . GLU A 1 189 ? 59.46900 14.67900 97.98300  1.000 137.59000 ?  731  GLU AAZA CG  1 
ATOM   1192 C CD  . GLU A 1 189 ? 59.39700 13.21000 98.43200  1.000 144.89000 ?  731  GLU AAZA CD  1 
ATOM   1193 O OE1 . GLU A 1 189 ? 58.45600 12.48500 98.03500  1.000 147.64000 ?  731  GLU AAZA OE1 1 
ATOM   1194 O OE2 . GLU A 1 189 ? 60.29900 12.77800 99.18500  1.000 149.13000 ?  731  GLU AAZA OE2 1 
ATOM   1195 N N   . SER A 1 190 ? 56.52400 17.01500 95.04400  1.000 113.30000 ?  732  SER AAZA N   1 
ATOM   1196 C CA  . SER A 1 190 ? 55.63400 17.03200 93.89200  1.000 108.76000 ?  732  SER AAZA CA  1 
ATOM   1197 C C   . SER A 1 190 ? 55.97200 18.17700 92.94300  1.000 106.71000 ?  732  SER AAZA C   1 
ATOM   1198 O O   . SER A 1 190 ? 55.93100 18.00800 91.72000  1.000 104.91000 ?  732  SER AAZA O   1 
ATOM   1199 C CB  . SER A 1 190 ? 54.18600 17.13800 94.37600  1.000 109.10000 ?  732  SER AAZA CB  1 
ATOM   1200 O OG  . SER A 1 190 ? 53.27300 17.03900 93.30200  1.000 107.44000 ?  732  SER AAZA OG  1 
ATOM   1201 N N   . ILE A 1 191 ? 56.31400 19.34600 93.48700  1.000 105.80000 ?  733  ILE AAZA N   1 
ATOM   1202 C CA  . ILE A 1 191 ? 56.61400 20.49600 92.64200  1.000 99.81000  ?  733  ILE AAZA CA  1 
ATOM   1203 C C   . ILE A 1 191 ? 57.95500 20.32400 91.94800  1.000 101.31000 ?  733  ILE AAZA C   1 
ATOM   1204 O O   . ILE A 1 191 ? 58.09500 20.63200 90.76100  1.000 103.54000 ?  733  ILE AAZA O   1 
ATOM   1205 C CB  . ILE A 1 191 ? 56.56600 21.79300 93.46600  1.000 97.22000  ?  733  ILE AAZA CB  1 
ATOM   1206 C CG1 . ILE A 1 191 ? 55.12400 22.06600 93.91000  1.000 94.70000  ?  733  ILE AAZA CG1 1 
ATOM   1207 C CG2 . ILE A 1 191 ? 57.15900 22.93300 92.67100  1.000 89.70000  ?  733  ILE AAZA CG2 1 
ATOM   1208 C CD1 . ILE A 1 191 ? 54.95300 23.22300 94.87900  1.000 91.76000  ?  733  ILE AAZA CD1 1 
ATOM   1209 N N   . THR A 1 192 ? 58.96200 19.82200 92.66500  1.000 104.33000 ?  734  THR AAZA N   1 
ATOM   1210 C CA  . THR A 1 192 ? 60.28700 19.68100 92.06700  1.000 103.52000 ?  734  THR AAZA CA  1 
ATOM   1211 C C   . THR A 1 192 ? 60.30900 18.59100 90.99800  1.000 103.14000 ?  734  THR AAZA C   1 
ATOM   1212 O O   . THR A 1 192 ? 61.02600 18.71900 89.99700  1.000 102.40000 ?  734  THR AAZA O   1 
ATOM   1213 C CB  . THR A 1 192 ? 61.33100 19.39500 93.14400  1.000 100.45000 ?  734  THR AAZA CB  1 
ATOM   1214 O OG1 . THR A 1 192 ? 60.93200 18.23100 93.86600  1.000 112.58000 ?  734  THR AAZA OG1 1 
ATOM   1215 C CG2 . THR A 1 192 ? 61.44600 20.56000 94.11700  1.000 96.43000  ?  734  THR AAZA CG2 1 
ATOM   1216 N N   . LYS A 1 193 ? 59.54800 17.50600 91.18200  1.000 100.58000 ?  735  LYS AAZA N   1 
ATOM   1217 C CA  . LYS A 1 193 ? 59.38400 16.56900 90.07300  1.000 104.48000 ?  735  LYS AAZA CA  1 
ATOM   1218 C C   . LYS A 1 193 ? 58.81200 17.27200 88.85100  1.000 106.78000 ?  735  LYS AAZA C   1 
ATOM   1219 O O   . LYS A 1 193 ? 59.38600 17.20100 87.75600  1.000 104.28000 ?  735  LYS AAZA O   1 
ATOM   1220 C CB  . LYS A 1 193 ? 58.49800 15.38500 90.46100  1.000 106.50000 ?  735  LYS AAZA CB  1 
ATOM   1221 C CG  . LYS A 1 193 ? 59.20400 14.32100 91.26600  1.000 115.74000 ?  735  LYS AAZA CG  1 
ATOM   1222 C CD  . LYS A 1 193 ? 58.44700 12.99900 91.16900  1.000 124.81000 ?  735  LYS AAZA CD  1 
ATOM   1223 C CE  . LYS A 1 193 ? 59.20600 11.87000 91.86100  1.000 128.05000 ?  735  LYS AAZA CE  1 
ATOM   1224 N NZ  . LYS A 1 193 ? 58.58200 10.54100 91.58700  1.000 130.89000 ?  735  LYS AAZA NZ  1 
ATOM   1225 N N   . ILE A 1 194 ? 57.67300 17.95400 89.02800  1.000 108.09000 ?  736  ILE AAZA N   1 
ATOM   1226 C CA  . ILE A 1 194 ? 57.03900 18.71200 87.94600  1.000 103.68000 ?  736  ILE AAZA CA  1 
ATOM   1227 C C   . ILE A 1 194 ? 58.06700 19.57900 87.23400  1.000 100.92000 ?  736  ILE AAZA C   1 
ATOM   1228 O O   . ILE A 1 194 ? 58.19900 19.53100 86.00700  1.000 103.29000 ?  736  ILE AAZA O   1 
ATOM   1229 C CB  . ILE A 1 194 ? 55.87700 19.55900 88.50200  1.000 102.72000 ?  736  ILE AAZA CB  1 
ATOM   1230 C CG1 . ILE A 1 194 ? 54.62300 18.71500 88.67400  1.000 104.99000 ?  736  ILE AAZA CG1 1 
ATOM   1231 C CG2 . ILE A 1 194 ? 55.55700 20.73800 87.59900  1.000 99.09000  ?  736  ILE AAZA CG2 1 
ATOM   1232 C CD1 . ILE A 1 194 ? 53.48200 19.48900 89.28400  1.000 103.75000 ?  736  ILE AAZA CD1 1 
ATOM   1233 N N   . ILE A 1 195 ? 58.82700 20.36600 88.00400  1.000 100.29000 ?  737  ILE AAZA N   1 
ATOM   1234 C CA  . ILE A 1 195 ? 59.83000 21.26000 87.42800  1.000 96.28000  ?  737  ILE AAZA CA  1 
ATOM   1235 C C   . ILE A 1 195 ? 60.75500 20.49600 86.48900  1.000 105.55000 ?  737  ILE AAZA C   1 
ATOM   1236 O O   . ILE A 1 195 ? 60.92300 20.86000 85.31600  1.000 109.07000 ?  737  ILE AAZA O   1 
ATOM   1237 C CB  . ILE A 1 195 ? 60.62500 21.95700 88.54000  1.000 91.95000  ?  737  ILE AAZA CB  1 
ATOM   1238 C CG1 . ILE A 1 195 ? 59.74000 22.97100 89.25000  1.000 88.08000  ?  737  ILE AAZA CG1 1 
ATOM   1239 C CG2 . ILE A 1 195 ? 61.83000 22.63200 87.94300  1.000 90.87000  ?  737  ILE AAZA CG2 1 
ATOM   1240 C CD1 . ILE A 1 195 ? 60.50200 23.97400 90.06900  1.000 81.17000  ?  737  ILE AAZA CD1 1 
ATOM   1241 N N   . GLN A 1 196 ? 61.35300 19.40900 86.98300  1.000 105.89000 ?  738  GLN AAZA N   1 
ATOM   1242 C CA  . GLN A 1 196 ? 62.26200 18.63800 86.14200  1.000 106.50000 ?  738  GLN AAZA CA  1 
ATOM   1243 C C   . GLN A 1 196 ? 61.56300 18.08300 84.90200  1.000 105.52000 ?  738  GLN AAZA C   1 
ATOM   1244 O O   . GLN A 1 196 ? 62.09100 18.20300 83.79100  1.000 108.60000 ?  738  GLN AAZA O   1 
ATOM   1245 C CB  . GLN A 1 196 ? 62.90900 17.53200 86.96000  1.000 111.58000 ?  738  GLN AAZA CB  1 
ATOM   1246 C CG  . GLN A 1 196 ? 63.78800 18.08400 88.07200  1.000 119.31000 ?  738  GLN AAZA CG  1 
ATOM   1247 C CD  . GLN A 1 196 ? 64.43700 16.98400 88.89300  1.000 135.36000 ?  738  GLN AAZA CD  1 
ATOM   1248 O OE1 . GLN A 1 196 ? 64.36900 15.80300 88.53700  1.000 142.35000 ?  738  GLN AAZA OE1 1 
ATOM   1249 N NE2 . GLN A 1 196 ? 65.07600 17.36400 89.99600  1.000 130.88000 ?  738  GLN AAZA NE2 1 
ATOM   1250 N N   . ARG A 1 197 ? 60.37400 17.48900 85.05900  1.000 105.10000 ?  739  ARG AAZA N   1 
ATOM   1251 C CA  . ARG A 1 197 ? 59.63500 17.00700 83.89100  1.000 103.38000 ?  739  ARG AAZA CA  1 
ATOM   1252 C C   . ARG A 1 197 ? 59.50500 18.09700 82.84300  1.000 108.35000 ?  739  ARG AAZA C   1 
ATOM   1253 O O   . ARG A 1 197 ? 59.69800 17.85400 81.64900  1.000 109.52000 ?  739  ARG AAZA O   1 
ATOM   1254 C CB  . ARG A 1 197 ? 58.23200 16.54000 84.27000  1.000 105.27000 ?  739  ARG AAZA CB  1 
ATOM   1255 C CG  . ARG A 1 197 ? 57.47300 15.90900 83.09800  1.000 106.91000 ?  739  ARG AAZA CG  1 
ATOM   1256 C CD  . ARG A 1 197 ? 55.97200 16.04800 83.28500  1.000 110.75000 ?  739  ARG AAZA CD  1 
ATOM   1257 N NE  . ARG A 1 197 ? 55.56700 15.68100 84.63600  1.000 125.04000 ?  739  ARG AAZA NE  1 
ATOM   1258 C CZ  . ARG A 1 197 ? 54.64300 16.32400 85.34300  1.000 125.28000 ?  739  ARG AAZA CZ  1 
ATOM   1259 N NH1 . ARG A 1 197 ? 53.98500 17.36300 84.84100  1.000 120.24000 ?  739  ARG AAZA NH1 1 
ATOM   1260 N NH2 . ARG A 1 197 ? 54.37400 15.91800 86.58600  1.000 120.15000 ?  739  ARG AAZA NH2 1 
ATOM   1261 N N   . LYS A 1 198 ? 59.15100 19.31400 83.27700  1.000 109.51000 ?  740  LYS AAZA N   1 
ATOM   1262 C CA  . LYS A 1 198 ? 58.87600 20.40800 82.34900  1.000 107.53000 ?  740  LYS AAZA CA  1 
ATOM   1263 C C   . LYS A 1 198 ? 60.13600 20.92200 81.66300  1.000 111.64000 ?  740  LYS AAZA C   1 
ATOM   1264 O O   . LYS A 1 198 ? 60.02500 21.65100 80.66800  1.000 110.91000 ?  740  LYS AAZA O   1 
ATOM   1265 C CB  . LYS A 1 198 ? 58.15800 21.54500 83.08300  1.000 95.42000  ?  740  LYS AAZA CB  1 
ATOM   1266 C CG  . LYS A 1 198 ? 56.64500 21.32000 83.25700  1.000 95.01000  ?  740  LYS AAZA CG  1 
ATOM   1267 C CD  . LYS A 1 198 ? 55.84600 21.77000 82.05300  1.000 96.41000  ?  740  LYS AAZA CD  1 
ATOM   1268 C CE  . LYS A 1 198 ? 54.34700 21.61700 82.27000  1.000 100.45000 ?  740  LYS AAZA CE  1 
ATOM   1269 N NZ  . LYS A 1 198 ? 53.53700 22.23500 81.16500  1.000 110.11000 ?  740  LYS AAZA NZ  1 
ATOM   1270 N N   . LYS A 1 199 ? 61.31300 20.52400 82.13300  1.000 111.02000 ?  741  LYS AAZA N   1 
ATOM   1271 C CA  . LYS A 1 199 ? 62.59000 20.94600 81.55700  1.000 110.75000 ?  741  LYS AAZA CA  1 
ATOM   1272 C C   . LYS A 1 199 ? 63.16000 19.93500 80.55700  1.000 118.39000 ?  741  LYS AAZA C   1 
ATOM   1273 O O   . LYS A 1 199 ? 64.34700 19.61600 80.64500  1.000 117.78000 ?  741  LYS AAZA O   1 
ATOM   1274 C CB  . LYS A 1 199 ? 63.59000 21.20700 82.67300  1.000 96.57000  ?  741  LYS AAZA CB  1 
ATOM   1275 C CG  . LYS A 1 199 ? 63.15600 22.25900 83.62500  1.000 91.93000  ?  741  LYS AAZA CG  1 
ATOM   1276 C CD  . LYS A 1 199 ? 64.36000 22.94900 84.25900  1.000 92.75000  ?  741  LYS AAZA CD  1 
ATOM   1277 C CE  . LYS A 1 199 ? 64.54900 22.62800 85.74500  1.000 98.59000  ?  741  LYS AAZA CE  1 
ATOM   1278 N NZ  . LYS A 1 199 ? 65.59200 23.47100 86.44300  1.000 84.63000  ?  741  LYS AAZA NZ  1 
ATOM   1279 N N   . ILE A 1 200 ? 62.30900 19.32700 79.73200  1.000 118.87000 ?  742  ILE AAZA N   1 
ATOM   1280 C CA  . ILE A 1 200 ? 62.82100 18.25100 78.83300  1.000 119.04000 ?  742  ILE AAZA CA  1 
ATOM   1281 C C   . ILE A 1 200 ? 62.25600 18.47600 77.43200  1.000 125.14000 ?  742  ILE AAZA C   1 
ATOM   1282 O O   . ILE A 1 200 ? 61.99600 17.48000 76.73200  1.000 128.42000 ?  742  ILE AAZA O   1 
ATOM   1283 C CB  . ILE A 1 200 ? 62.46100 16.85800 79.38100  1.000 120.23000 ?  742  ILE AAZA CB  1 
ATOM   1284 C CG1 . ILE A 1 200 ? 60.95100 16.60900 79.34900  1.000 123.22000 ?  742  ILE AAZA CG1 1 
ATOM   1285 C CG2 . ILE A 1 200 ? 63.03500 16.65700 80.77400  1.000 113.12000 ?  742  ILE AAZA CG2 1 
ATOM   1286 C CD1 . ILE A 1 200 ? 60.53600 15.28500 79.94500  1.000 122.36000 ?  742  ILE AAZA CD1 1 
ATOM   1287 N N   . ALA A 1 201 ? 62.09200 19.74000 77.04300  1.000 128.96000 ?  743  ALA AAZA N   1 
ATOM   1288 C CA  . ALA A 1 201 ? 61.58800 20.05900 75.68800  1.000 129.40000 ?  743  ALA AAZA CA  1 
ATOM   1289 C C   . ALA A 1 201 ? 62.31600 19.19500 74.65000  1.000 119.79000 ?  743  ALA AAZA C   1 
ATOM   1290 O O   . ALA A 1 201 ? 63.51400 18.92600 74.86300  1.000 105.74000 ?  743  ALA AAZA O   1 
ATOM   1291 C CB  . ALA A 1 201 ? 61.77000 21.53100 75.41900  1.000 118.65000 ?  743  ALA AAZA CB  1 
ATOM   1292 N N   . ILE A 1 210 ? 50.11900 6.84200  66.68100  1.000 146.50000 ?  752  ILE AAZA N   1 
ATOM   1293 C CA  . ILE A 1 210 ? 48.97000 7.79100  66.73800  1.000 145.99000 ?  752  ILE AAZA CA  1 
ATOM   1294 C C   . ILE A 1 210 ? 47.96200 7.27700  67.76800  1.000 147.48000 ?  752  ILE AAZA C   1 
ATOM   1295 O O   . ILE A 1 210 ? 47.32900 8.11400  68.43700  1.000 148.46000 ?  752  ILE AAZA O   1 
ATOM   1296 C CB  . ILE A 1 210 ? 48.32900 7.95000  65.34800  1.000 146.49000 ?  752  ILE AAZA CB  1 
ATOM   1297 C CG1 . ILE A 1 210 ? 49.37400 8.27000  64.27700  1.000 148.37000 ?  752  ILE AAZA CG1 1 
ATOM   1298 C CG2 . ILE A 1 210 ? 47.22000 8.99100  65.38400  1.000 141.30000 ?  752  ILE AAZA CG2 1 
ATOM   1299 C CD1 . ILE A 1 210 ? 48.79000 8.56000  62.91400  1.000 136.77000 ?  752  ILE AAZA CD1 1 
ATOM   1300 N N   . THR A 1 211 ? 47.82400 5.95500  67.88300  1.000 149.93000 ?  753  THR AAZA N   1 
ATOM   1301 C CA  . THR A 1 211 ? 46.91100 5.36300  68.89500  1.000 152.12000 ?  753  THR AAZA CA  1 
ATOM   1302 C C   . THR A 1 211 ? 45.46900 5.78800  68.61100  1.000 151.04000 ?  753  THR AAZA C   1 
ATOM   1303 O O   . THR A 1 211 ? 44.86000 6.42600  69.48900  1.000 152.71000 ?  753  THR AAZA O   1 
ATOM   1304 C CB  . THR A 1 211 ? 47.31900 5.77300  70.31600  1.000 152.46000 ?  753  THR AAZA CB  1 
ATOM   1305 O OG1 . THR A 1 211 ? 48.73800 5.66400  70.42400  1.000 153.93000 ?  753  THR AAZA OG1 1 
ATOM   1306 C CG2 . THR A 1 211 ? 46.65800 4.93100  71.38600  1.000 145.14000 ?  753  THR AAZA CG2 1 
ATOM   1307 N N   . PHE A 1 212 ? 44.94800 5.45500  67.43000  1.000 148.92000 ?  754  PHE AAZA N   1 
ATOM   1308 C CA  . PHE A 1 212 ? 43.52000 5.75200  67.15600  1.000 146.91000 ?  754  PHE AAZA CA  1 
ATOM   1309 C C   . PHE A 1 212 ? 42.66100 4.88500  68.07900  1.000 150.22000 ?  754  PHE AAZA C   1 
ATOM   1310 O O   . PHE A 1 212 ? 42.93900 3.67800  68.19300  1.000 148.88000 ?  754  PHE AAZA O   1 
ATOM   1311 C CB  . PHE A 1 212 ? 43.15400 5.47000  65.69900  1.000 143.66000 ?  754  PHE AAZA CB  1 
ATOM   1312 C CG  . PHE A 1 212 ? 44.01300 6.14700  64.66200  1.000 144.43000 ?  754  PHE AAZA CG  1 
ATOM   1313 C CD1 . PHE A 1 212 ? 45.32800 5.76000  64.46100  1.000 145.84000 ?  754  PHE AAZA CD1 1 
ATOM   1314 C CD2 . PHE A 1 212 ? 43.50600 7.17700  63.88700  1.000 137.19000 ?  754  PHE AAZA CD2 1 
ATOM   1315 C CE1 . PHE A 1 212 ? 46.11000 6.37900  63.50000  1.000 144.24000 ?  754  PHE AAZA CE1 1 
ATOM   1316 C CE2 . PHE A 1 212 ? 44.29100 7.79900  62.93100  1.000 124.12000 ?  754  PHE AAZA CE2 1 
ATOM   1317 C CZ  . PHE A 1 212 ? 45.59100 7.40000  62.74000  1.000 132.50000 ?  754  PHE AAZA CZ  1 
ATOM   1318 N N   . GLN A 1 213 ? 41.65400 5.48500  68.71600  1.000 156.77000 ?  755  GLN AAZA N   1 
ATOM   1319 C CA  . GLN A 1 213 ? 40.74600 4.72100  69.61100  1.000 154.82000 ?  755  GLN AAZA CA  1 
ATOM   1320 C C   . GLN A 1 213 ? 39.96600 3.70200  68.77700  1.000 152.49000 ?  755  GLN AAZA C   1 
ATOM   1321 O O   . GLN A 1 213 ? 39.95700 2.51400  69.15100  1.000 157.33000 ?  755  GLN AAZA O   1 
ATOM   1322 C CB  . GLN A 1 213 ? 39.77800 5.66400  70.32500  1.000 151.88000 ?  755  GLN AAZA CB  1 
ATOM   1323 C CG  . GLN A 1 213 ? 38.77000 4.94000  71.20500  1.000 154.98000 ?  755  GLN AAZA CG  1 
ATOM   1324 C CD  . GLN A 1 213 ? 39.44200 3.99300  72.16900  1.000 160.31000 ?  755  GLN AAZA CD  1 
ATOM   1325 O OE1 . GLN A 1 213 ? 40.25500 4.39400  72.99900  1.000 155.58000 ?  755  GLN AAZA OE1 1 
ATOM   1326 N NE2 . GLN A 1 213 ? 39.10600 2.71800  72.06200  1.000 158.32000 ?  755  GLN AAZA NE2 1 
ATOM   1327 N N   . SER A 1 214 ? 39.35000 4.15800  67.68700  1.000 142.80000 ?  756  SER AAZA N   1 
ATOM   1328 C CA  . SER A 1 214 ? 38.57700 3.24700  66.80800  1.000 137.16000 ?  756  SER AAZA CA  1 
ATOM   1329 C C   . SER A 1 214 ? 39.36100 3.02600  65.51500  1.000 135.05000 ?  756  SER AAZA C   1 
ATOM   1330 O O   . SER A 1 214 ? 40.54900 3.39100  65.48100  1.000 136.39000 ?  756  SER AAZA O   1 
ATOM   1331 C CB  . SER A 1 214 ? 37.20900 3.80500  66.52900  1.000 134.01000 ?  756  SER AAZA CB  1 
ATOM   1332 O OG  . SER A 1 214 ? 36.48400 2.96100  65.64800  1.000 130.55000 ?  756  SER AAZA OG  1 
ATOM   1333 N N   . SER A 1 215 ? 38.71600 2.45300  64.50000  1.000 128.51000 ?  757  SER AAZA N   1 
ATOM   1334 C CA  . SER A 1 215 ? 39.38700 2.26400  63.19100  1.000 121.83000 ?  757  SER AAZA CA  1 
ATOM   1335 C C   . SER A 1 215 ? 39.03300 3.43100  62.27200  1.000 119.05000 ?  757  SER AAZA C   1 
ATOM   1336 O O   . SER A 1 215 ? 37.83800 3.62000  61.99700  1.000 121.59000 ?  757  SER AAZA O   1 
ATOM   1337 C CB  . SER A 1 215 ? 38.99600 0.95500  62.57300  1.000 118.38000 ?  757  SER AAZA CB  1 
ATOM   1338 O OG  . SER A 1 215 ? 39.55900 0.82700  61.27700  1.000 118.28000 ?  757  SER AAZA OG  1 
ATOM   1339 N N   . PRO A 1 216 ? 40.01200 4.20500  61.76700  1.000 115.06000 ?  758  PRO AAZA N   1 
ATOM   1340 C CA  . PRO A 1 216 ? 39.71400 5.27300  60.80400  1.000 112.13000 ?  758  PRO AAZA CA  1 
ATOM   1341 C C   . PRO A 1 216 ? 39.06300 4.70400  59.55900  1.000 112.22000 ?  758  PRO AAZA C   1 
ATOM   1342 O O   . PRO A 1 216 ? 39.16100 3.49400  59.31300  1.000 115.66000 ?  758  PRO AAZA O   1 
ATOM   1343 C CB  . PRO A 1 216 ? 41.09900 5.85400  60.48200  1.000 115.66000 ?  758  PRO AAZA CB  1 
ATOM   1344 C CG  . PRO A 1 216 ? 42.01400 5.33500  61.55700  1.000 118.63000 ?  758  PRO AAZA CG  1 
ATOM   1345 C CD  . PRO A 1 216 ? 41.45800 4.02000  61.95900  1.000 119.66000 ?  758  PRO AAZA CD  1 
ATOM   1346 N N   . PRO A 1 217 ? 38.38200 5.52300  58.75700  1.000 111.21000 ?  759  PRO AAZA N   1 
ATOM   1347 C CA  . PRO A 1 217 ? 37.85000 5.03100  57.48600  1.000 107.96000 ?  759  PRO AAZA CA  1 
ATOM   1348 C C   . PRO A 1 217 ? 38.94100 4.94000  56.42800  1.000 104.24000 ?  759  PRO AAZA C   1 
ATOM   1349 O O   . PRO A 1 217 ? 40.05000 5.45400  56.56500  1.000 104.60000 ?  759  PRO AAZA O   1 
ATOM   1350 C CB  . PRO A 1 217 ? 36.78600 6.06500  57.10600  1.000 99.55000  ?  759  PRO AAZA CB  1 
ATOM   1351 C CG  . PRO A 1 217 ? 37.23800 7.28900  57.72000  1.000 103.12000 ?  759  PRO AAZA CG  1 
ATOM   1352 C CD  . PRO A 1 217 ? 37.92700 6.89700  59.02200  1.000 111.66000 ?  759  PRO AAZA CD  1 
ATOM   1353 N N   . THR A 1 218 ? 38.60100 4.23000  55.37100  1.000 101.10000 ?  760  THR AAZA N   1 
ATOM   1354 C CA  . THR A 1 218 ? 39.52100 4.01400  54.27600  1.000 102.67000 ?  760  THR AAZA CA  1 
ATOM   1355 C C   . THR A 1 218 ? 39.72800 5.32300  53.51200  1.000 102.12000 ?  760  THR AAZA C   1 
ATOM   1356 O O   . THR A 1 218 ? 38.81100 6.14200  53.39300  1.000 104.96000 ?  760  THR AAZA O   1 
ATOM   1357 C CB  . THR A 1 218 ? 38.96000 2.87300  53.40700  1.000 111.41000 ?  760  THR AAZA CB  1 
ATOM   1358 O OG1 . THR A 1 218 ? 39.80200 2.61400  52.27900  1.000 109.98000 ?  760  THR AAZA OG1 1 
ATOM   1359 C CG2 . THR A 1 218 ? 37.51100 3.15300  52.96900  1.000 115.59000 ?  760  THR AAZA CG2 1 
ATOM   1360 N N   . VAL A 1 219 ? 40.94900 5.51800  53.00600  1.000 98.19000  ?  761  VAL AAZA N   1 
ATOM   1361 C CA  . VAL A 1 219 ? 41.41300 6.80500  52.47300  1.000 91.65000  ?  761  VAL AAZA CA  1 
ATOM   1362 C C   . VAL A 1 219 ? 41.05300 6.93600  50.99300  1.000 92.01000  ?  761  VAL AAZA C   1 
ATOM   1363 O O   . VAL A 1 219 ? 41.73000 6.37100  50.13200  1.000 92.65000  ?  761  VAL AAZA O   1 
ATOM   1364 C CB  . VAL A 1 219 ? 42.92400 6.95200  52.66700  1.000 87.38000  ?  761  VAL AAZA CB  1 
ATOM   1365 C CG1 . VAL A 1 219 ? 43.42900 8.27600  52.11700  1.000 81.87000  ?  761  VAL AAZA CG1 1 
ATOM   1366 C CG2 . VAL A 1 219 ? 43.26400 6.77800  54.12100  1.000 98.16000  ?  761  VAL AAZA CG2 1 
ATOM   1367 N N   . GLU A 1 220 ? 40.04300 7.75600  50.69200  1.000 92.79000  ?  762  GLU AAZA N   1 
ATOM   1368 C CA  . GLU A 1 220 ? 39.51300 7.87400  49.33300  1.000 95.30000  ?  762  GLU AAZA CA  1 
ATOM   1369 C C   . GLU A 1 220 ? 40.50100 8.50300  48.35500  1.000 93.96000  ?  762  GLU AAZA C   1 
ATOM   1370 O O   . GLU A 1 220 ? 41.02000 9.59600  48.60000  1.000 92.05000  ?  762  GLU AAZA O   1 
ATOM   1371 C CB  . GLU A 1 220 ? 38.25100 8.71900  49.35800  1.000 94.53000  ?  762  GLU AAZA CB  1 
ATOM   1372 C CG  . GLU A 1 220 ? 37.24700 8.20400  50.30900  1.000 100.65000 ?  762  GLU AAZA CG  1 
ATOM   1373 C CD  . GLU A 1 220 ? 36.43400 7.10200  49.69500  1.000 113.86000 ?  762  GLU AAZA CD  1 
ATOM   1374 O OE1 . GLU A 1 220 ? 36.49900 6.94700  48.44900  1.000 112.82000 ?  762  GLU AAZA OE1 1 
ATOM   1375 O OE2 . GLU A 1 220 ? 35.75200 6.38500  50.46200  1.000 121.46000 ?  762  GLU AAZA OE2 1 
ATOM   1376 N N   . TRP A 1 221 ? 40.63300 7.85200  47.19900  1.000 90.81000  ?  763  TRP AAZA N   1 
ATOM   1377 C CA  . TRP A 1 221 ? 41.44600 8.43200  46.10600  1.000 88.63000  ?  763  TRP AAZA CA  1 
ATOM   1378 C C   . TRP A 1 221 ? 40.55000 8.50400  44.86900  1.000 89.10000  ?  763  TRP AAZA C   1 
ATOM   1379 O O   . TRP A 1 221 ? 39.75300 7.57400  44.67900  1.000 95.48000  ?  763  TRP AAZA O   1 
ATOM   1380 C CB  . TRP A 1 221 ? 42.71700 7.62000  45.85200  1.000 86.88000  ?  763  TRP AAZA CB  1 
ATOM   1381 C CG  . TRP A 1 221 ? 43.73300 7.70400  46.94700  1.000 84.34000  ?  763  TRP AAZA CG  1 
ATOM   1382 C CD1 . TRP A 1 221 ? 43.70300 7.06500  48.15100  1.000 83.41000  ?  763  TRP AAZA CD1 1 
ATOM   1383 C CD2 . TRP A 1 221 ? 44.92800 8.50300  46.94700  1.000 89.77000  ?  763  TRP AAZA CD2 1 
ATOM   1384 N NE1 . TRP A 1 221 ? 44.80400 7.39600  48.89100  1.000 91.46000  ?  763  TRP AAZA NE1 1 
ATOM   1385 C CE2 . TRP A 1 221 ? 45.57300 8.27900  48.18100  1.000 93.34000  ?  763  TRP AAZA CE2 1 
ATOM   1386 C CE3 . TRP A 1 221 ? 45.51800 9.37700  46.02800  1.000 93.02000  ?  763  TRP AAZA CE3 1 
ATOM   1387 C CZ2 . TRP A 1 221 ? 46.77500 8.89800  48.51400  1.000 91.63000  ?  763  TRP AAZA CZ2 1 
ATOM   1388 C CZ3 . TRP A 1 221 ? 46.70500 9.98900  46.35900  1.000 90.02000  ?  763  TRP AAZA CZ3 1 
ATOM   1389 C CH2 . TRP A 1 221 ? 47.32300 9.75100  47.58600  1.000 91.07000  ?  763  TRP AAZA CH2 1 
ATOM   1390 N N   . HIS A 1 222 ? 40.65500 9.57000  44.08400  1.000 89.84000  ?  764  HIS AAZA N   1 
ATOM   1391 C CA  . HIS A 1 222 ? 39.86400 9.79800  42.88800  1.000 91.55000  ?  764  HIS AAZA CA  1 
ATOM   1392 C C   . HIS A 1 222 ? 40.44500 9.79300  41.47700  1.000 93.21000  ?  764  HIS AAZA C   1 
ATOM   1393 O O   . HIS A 1 222 ? 40.29800 8.79700  40.76700  1.000 97.63000  ?  764  HIS AAZA O   1 
ATOM   1394 C CB  . HIS A 1 222 ? 39.16500 11.15800 42.97100  1.000 89.34000  ?  764  HIS AAZA CB  1 
ATOM   1395 C CG  . HIS A 1 222 ? 38.42700 11.53600 41.72800  1.000 91.17000  ?  764  HIS AAZA CG  1 
ATOM   1396 N ND1 . HIS A 1 222 ? 38.74100 12.66000 40.99400  1.000 87.69000  ?  764  HIS AAZA ND1 1 
ATOM   1397 C CD2 . HIS A 1 222 ? 37.42200 10.92100 41.06500  1.000 91.30000  ?  764  HIS AAZA CD2 1 
ATOM   1398 C CE1 . HIS A 1 222 ? 37.93200 12.74500 39.95500  1.000 85.59000  ?  764  HIS AAZA CE1 1 
ATOM   1399 N NE2 . HIS A 1 222 ? 37.12400 11.70300 39.97500  1.000 91.54000  ?  764  HIS AAZA NE2 1 
ATOM   1400 N N   . ILE A 1 223 ? 41.26300 10.75700 41.10100  1.000 87.72000  ?  765  ILE AAZA N   1 
ATOM   1401 C CA  . ILE A 1 223 ? 41.98500 10.67100 39.83700  1.000 85.24000  ?  765  ILE AAZA CA  1 
ATOM   1402 C C   . ILE A 1 223 ? 43.42100 10.44000 40.26900  1.000 91.91000  ?  765  ILE AAZA C   1 
ATOM   1403 O O   . ILE A 1 223 ? 44.02700 9.41800  39.93000  1.000 99.42000  ?  765  ILE AAZA O   1 
ATOM   1404 C CB  . ILE A 1 223 ? 41.88400 11.92000 38.95300  1.000 83.18000  ?  765  ILE AAZA CB  1 
ATOM   1405 C CG1 . ILE A 1 223 ? 40.52200 11.98000 38.26700  1.000 85.17000  ?  765  ILE AAZA CG1 1 
ATOM   1406 C CG2 . ILE A 1 223 ? 43.00300 11.89700 37.92500  1.000 72.93000  ?  765  ILE AAZA CG2 1 
ATOM   1407 C CD1 . ILE A 1 223 ? 40.34300 13.16600 37.29500  1.000 84.37000  ?  765  ILE AAZA CD1 1 
ATOM   1408 N N   . SER A 1 224 ? 43.98900 11.39000 41.01300  1.000 91.35000  ?  766  SER AAZA N   1 
ATOM   1409 C CA  . SER A 1 224 ? 45.40400 11.30700 41.34300  1.000 94.06000  ?  766  SER AAZA CA  1 
ATOM   1410 C C   . SER A 1 224 ? 45.67300 10.02400 42.10300  1.000 97.17000  ?  766  SER AAZA C   1 
ATOM   1411 O O   . SER A 1 224 ? 44.94400 9.68900  43.04200  1.000 98.24000  ?  766  SER AAZA O   1 
ATOM   1412 C CB  . SER A 1 224 ? 45.84500 12.52000 42.15900  1.000 91.19000  ?  766  SER AAZA CB  1 
ATOM   1413 O OG  . SER A 1 224 ? 45.86100 13.69500 41.36800  1.000 87.30000  ?  766  SER AAZA OG  1 
ATOM   1414 N N   . ARG A 1 225 ? 46.69200 9.28100  41.65300  1.000 96.85000  ?  767  ARG AAZA N   1 
ATOM   1415 C CA  . ARG A 1 225 ? 47.20300 8.02000  42.17800  1.000 100.15000 ?  767  ARG AAZA CA  1 
ATOM   1416 C C   . ARG A 1 225 ? 48.15600 8.28200  43.34000  1.000 102.31000 ?  767  ARG AAZA C   1 
ATOM   1417 O O   . ARG A 1 225 ? 48.95800 9.22100  43.27900  1.000 105.03000 ?  767  ARG AAZA O   1 
ATOM   1418 C CB  . ARG A 1 225 ? 47.94900 7.24400  41.09600  1.000 110.78000 ?  767  ARG AAZA CB  1 
ATOM   1419 C CG  . ARG A 1 225 ? 47.25300 6.01800  40.52400  1.000 110.12000 ?  767  ARG AAZA CG  1 
ATOM   1420 C CD  . ARG A 1 225 ? 48.26000 5.25500  39.65700  1.000 124.39000 ?  767  ARG AAZA CD  1 
ATOM   1421 N NE  . ARG A 1 225 ? 47.66500 4.50500  38.55400  1.000 139.20000 ?  767  ARG AAZA NE  1 
ATOM   1422 C CZ  . ARG A 1 225 ? 48.19000 4.42700  37.33700  1.000 139.68000 ?  767  ARG AAZA CZ  1 
ATOM   1423 N NH1 . ARG A 1 225 ? 49.32700 5.03500  37.03400  1.000 139.12000 ?  767  ARG AAZA NH1 1 
ATOM   1424 N NH2 . ARG A 1 225 ? 47.55900 3.72100  36.40200  1.000 136.60000 ?  767  ARG AAZA NH2 1 
ATOM   1425 N N   . PRO A 1 226 ? 48.09300 7.46300  44.39100  1.000 97.53000  ?  768  PRO AAZA N   1 
ATOM   1426 C CA  . PRO A 1 226 ? 49.03100 7.61900  45.51000  1.000 97.66000  ?  768  PRO AAZA CA  1 
ATOM   1427 C C   . PRO A 1 226 ? 50.47500 7.68100  45.03300  1.000 99.79000  ?  768  PRO AAZA C   1 
ATOM   1428 O O   . PRO A 1 226 ? 50.89600 6.91500  44.16600  1.000 102.77000 ?  768  PRO AAZA O   1 
ATOM   1429 C CB  . PRO A 1 226 ? 48.76400 6.37600  46.36200  1.000 89.90000  ?  768  PRO AAZA CB  1 
ATOM   1430 C CG  . PRO A 1 226 ? 47.35300 6.06700  46.09800  1.000 87.14000  ?  768  PRO AAZA CG  1 
ATOM   1431 C CD  . PRO A 1 226 ? 47.10200 6.41100  44.65900  1.000 92.70000  ?  768  PRO AAZA CD  1 
ATOM   1432 N N   . GLY A 1 227 ? 51.22400 8.62900  45.58700  1.000 98.56000  ?  769  GLY AAZA N   1 
ATOM   1433 C CA  . GLY A 1 227 ? 52.60700 8.82900  45.23400  1.000 104.61000 ?  769  GLY AAZA CA  1 
ATOM   1434 C C   . GLY A 1 227 ? 52.86000 9.77900  44.08600  1.000 110.44000 ?  769  GLY AAZA C   1 
ATOM   1435 O O   . GLY A 1 227 ? 54.02300 9.96600  43.70600  1.000 119.19000 ?  769  GLY AAZA O   1 
ATOM   1436 N N   . HIS A 1 228 ? 51.82500 10.37600 43.50800  1.000 108.90000 ?  770  HIS AAZA N   1 
ATOM   1437 C CA  . HIS A 1 228 ? 51.98900 11.25700 42.35000  1.000 116.68000 ?  770  HIS AAZA CA  1 
ATOM   1438 C C   . HIS A 1 228 ? 51.64500 12.68900 42.74000  1.000 113.45000 ?  770  HIS AAZA C   1 
ATOM   1439 O O   . HIS A 1 228 ? 50.66200 13.27000 42.27500  1.000 111.11000 ?  770  HIS AAZA O   1 
ATOM   1440 C CB  . HIS A 1 228 ? 51.12600 10.77900 41.15600  1.000 118.62000 ?  770  HIS AAZA CB  1 
ATOM   1441 C CG  . HIS A 1 228 ? 51.59400 9.50000  40.52700  1.000 126.00000 ?  770  HIS AAZA CG  1 
ATOM   1442 N ND1 . HIS A 1 228 ? 52.51700 8.66100  41.12100  1.000 122.38000 ?  770  HIS AAZA ND1 1 
ATOM   1443 C CD2 . HIS A 1 228 ? 51.25300 8.91500  39.35100  1.000 129.06000 ?  770  HIS AAZA CD2 1 
ATOM   1444 C CE1 . HIS A 1 228 ? 52.72400 7.61600  40.33800  1.000 127.43000 ?  770  HIS AAZA CE1 1 
ATOM   1445 N NE2 . HIS A 1 228 ? 51.96800 7.74500  39.25900  1.000 134.95000 ?  770  HIS AAZA NE2 1 
ATOM   1446 N N   . ILE A 1 229 ? 52.50300 13.27800 43.57500  1.000 110.39000 ?  771  ILE AAZA N   1 
ATOM   1447 C CA  . ILE A 1 229 ? 52.22200 14.59900 44.11000  1.000 108.30000 ?  771  ILE AAZA CA  1 
ATOM   1448 C C   . ILE A 1 229 ? 52.07400 15.63200 43.00200  1.000 106.12000 ?  771  ILE AAZA C   1 
ATOM   1449 O O   . ILE A 1 229 ? 51.42300 16.66300 43.19600  1.000 104.99000 ?  771  ILE AAZA O   1 
ATOM   1450 C CB  . ILE A 1 229 ? 53.34400 15.00700 45.06500  1.000 106.35000 ?  771  ILE AAZA CB  1 
ATOM   1451 C CG1 . ILE A 1 229 ? 53.73500 13.81100 45.90600  1.000 108.15000 ?  771  ILE AAZA CG1 1 
ATOM   1452 C CG2 . ILE A 1 229 ? 52.84400 16.10800 46.00100  1.000 104.53000 ?  771  ILE AAZA CG2 1 
ATOM   1453 C CD1 . ILE A 1 229 ? 55.05500 13.99600 46.58400  1.000 113.65000 ?  771  ILE AAZA CD1 1 
ATOM   1454 N N   . GLU A 1 230 ? 52.66800 15.37900 41.83800  1.000 106.33000 ?  772  GLU AAZA N   1 
ATOM   1455 C CA  . GLU A 1 230 ? 52.69500 16.37000 40.77100  1.000 111.87000 ?  772  GLU AAZA CA  1 
ATOM   1456 C C   . GLU A 1 230 ? 51.34200 16.54000 40.09100  1.000 109.99000 ?  772  GLU AAZA C   1 
ATOM   1457 O O   . GLU A 1 230 ? 51.11500 17.57100 39.44800  1.000 109.57000 ?  772  GLU AAZA O   1 
ATOM   1458 C CB  . GLU A 1 230 ? 53.74700 16.00700 39.71000  1.000 116.23000 ?  772  GLU AAZA CB  1 
ATOM   1459 C CG  . GLU A 1 230 ? 53.68500 14.56500 39.20800  1.000 118.26000 ?  772  GLU AAZA CG  1 
ATOM   1460 C CD  . GLU A 1 230 ? 54.29900 13.55300 40.17100  1.000 128.55000 ?  772  GLU AAZA CD  1 
ATOM   1461 O OE1 . GLU A 1 230 ? 54.94000 13.97400 41.16800  1.000 122.95000 ?  772  GLU AAZA OE1 1 
ATOM   1462 O OE2 . GLU A 1 230 ? 54.10100 12.33300 39.94600  1.000 131.18000 ?  772  GLU AAZA OE2 1 
ATOM   1463 N N   . THR A 1 231 ? 50.44500 15.56100 40.20500  1.000 104.85000 ?  773  THR AAZA N   1 
ATOM   1464 C CA  . THR A 1 231 ? 49.10100 15.70100 39.65600  1.000 102.38000 ?  773  THR AAZA CA  1 
ATOM   1465 C C   . THR A 1 231 ? 48.09000 16.25200 40.64900  1.000 99.80000  ?  773  THR AAZA C   1 
ATOM   1466 O O   . THR A 1 231 ? 46.98500 16.61200 40.22600  1.000 92.79000  ?  773  THR AAZA O   1 
ATOM   1467 C CB  . THR A 1 231 ? 48.57900 14.36000 39.15600  1.000 100.08000 ?  773  THR AAZA CB  1 
ATOM   1468 O OG1 . THR A 1 231 ? 48.74700 13.38700 40.19400  1.000 106.10000 ?  773  THR AAZA OG1 1 
ATOM   1469 C CG2 . THR A 1 231 ? 49.28300 13.92800 37.88000  1.000 97.18000  ?  773  THR AAZA CG2 1 
ATOM   1470 N N   . PHE A 1 232 ? 48.44400 16.30100 41.94400  1.000 103.41000 ?  774  PHE AAZA N   1 
ATOM   1471 C CA  . PHE A 1 232 ? 47.56100 16.77300 43.01200  1.000 94.96000  ?  774  PHE AAZA CA  1 
ATOM   1472 C C   . PHE A 1 232 ? 47.03300 18.17200 42.71400  1.000 90.96000  ?  774  PHE AAZA C   1 
ATOM   1473 O O   . PHE A 1 232 ? 47.81400 19.10900 42.54100  1.000 97.21000  ?  774  PHE AAZA O   1 
ATOM   1474 C CB  . PHE A 1 232 ? 48.31800 16.78300 44.34500  1.000 96.47000  ?  774  PHE AAZA CB  1 
ATOM   1475 C CG  . PHE A 1 232 ? 48.43200 15.42700 45.02000  1.000 101.75000 ?  774  PHE AAZA CG  1 
ATOM   1476 C CD1 . PHE A 1 232 ? 47.90700 14.28500 44.43400  1.000 99.33000  ?  774  PHE AAZA CD1 1 
ATOM   1477 C CD2 . PHE A 1 232 ? 49.08100 15.30500 46.25100  1.000 100.42000 ?  774  PHE AAZA CD2 1 
ATOM   1478 C CE1 . PHE A 1 232 ? 48.02100 13.05400 45.06300  1.000 98.73000  ?  774  PHE AAZA CE1 1 
ATOM   1479 C CE2 . PHE A 1 232 ? 49.19800 14.08300 46.87600  1.000 97.39000  ?  774  PHE AAZA CE2 1 
ATOM   1480 C CZ  . PHE A 1 232 ? 48.66800 12.95900 46.28200  1.000 100.94000 ?  774  PHE AAZA CZ  1 
ATOM   1481 N N   . ASP A 1 233 ? 45.71100 18.31000 42.65100  1.000 86.14000  ?  775  ASP AAZA N   1 
ATOM   1482 C CA  . ASP A 1 233 ? 45.04900 19.59900 42.48100  1.000 85.95000  ?  775  ASP AAZA CA  1 
ATOM   1483 C C   . ASP A 1 233 ? 43.62200 19.44700 42.99100  1.000 82.33000  ?  775  ASP AAZA C   1 
ATOM   1484 O O   . ASP A 1 233 ? 43.20000 18.35800 43.39200  1.000 80.36000  ?  775  ASP AAZA O   1 
ATOM   1485 C CB  . ASP A 1 233 ? 45.08500 20.08500 41.01900  1.000 88.24000  ?  775  ASP AAZA CB  1 
ATOM   1486 C CG  . ASP A 1 233 ? 44.88100 21.61500 40.88400  1.000 97.39000  ?  775  ASP AAZA CG  1 
ATOM   1487 O OD1 . ASP A 1 233 ? 45.11900 22.37000 41.86700  1.000 95.53000  ?  775  ASP AAZA OD1 1 
ATOM   1488 O OD2 . ASP A 1 233 ? 44.46500 22.06400 39.78800  1.000 102.00000 ?  775  ASP AAZA OD2 1 
ATOM   1489 N N   . LEU A 1 234 ? 42.88600 20.56200 42.97300  1.000 83.56000  ?  776  LEU AAZA N   1 
ATOM   1490 C CA  . LEU A 1 234 ? 41.53100 20.60100 43.51400  1.000 79.62000  ?  776  LEU AAZA CA  1 
ATOM   1491 C C   . LEU A 1 234 ? 40.65900 19.52600 42.88500  1.000 83.54000  ?  776  LEU AAZA C   1 
ATOM   1492 O O   . LEU A 1 234 ? 39.98300 18.76500 43.58900  1.000 83.00000  ?  776  LEU AAZA O   1 
ATOM   1493 C CB  . LEU A 1 234 ? 40.90800 21.96300 43.24000  1.000 75.71000  ?  776  LEU AAZA CB  1 
ATOM   1494 C CG  . LEU A 1 234 ? 39.74600 22.45900 44.08100  1.000 77.62000  ?  776  LEU AAZA CG  1 
ATOM   1495 C CD1 . LEU A 1 234 ? 39.45900 23.88100 43.65600  1.000 83.07000  ?  776  LEU AAZA CD1 1 
ATOM   1496 C CD2 . LEU A 1 234 ? 38.51600 21.62500 43.99800  1.000 87.30000  ?  776  LEU AAZA CD2 1 
ATOM   1497 N N   . LEU A 1 235 ? 40.64500 19.47400 41.54200  1.000 84.04000  ?  777  LEU AAZA N   1 
ATOM   1498 C CA  . LEU A 1 235 ? 39.68000 18.66500 40.80500  1.000 81.29000  ?  777  LEU AAZA CA  1 
ATOM   1499 C C   . LEU A 1 235 ? 40.09500 17.20400 40.67200  1.000 83.01000  ?  777  LEU AAZA C   1 
ATOM   1500 O O   . LEU A 1 235 ? 39.23800 16.36400 40.37700  1.000 79.89000  ?  777  LEU AAZA O   1 
ATOM   1501 C CB  . LEU A 1 235 ? 39.45700 19.26000 39.42200  1.000 76.81000  ?  777  LEU AAZA CB  1 
ATOM   1502 C CG  . LEU A 1 235 ? 38.40000 20.35500 39.37400  1.000 78.84000  ?  777  LEU AAZA CG  1 
ATOM   1503 C CD1 . LEU A 1 235 ? 38.00600 20.58700 37.94100  1.000 82.90000  ?  777  LEU AAZA CD1 1 
ATOM   1504 C CD2 . LEU A 1 235 ? 37.19900 20.04400 40.21900  1.000 69.09000  ?  777  LEU AAZA CD2 1 
ATOM   1505 N N   . THR A 1 236 ? 41.37400 16.88300 40.90100  1.000 84.52000  ?  778  THR AAZA N   1 
ATOM   1506 C CA  . THR A 1 236 ? 41.87800 15.52300 40.76300  1.000 82.37000  ?  778  THR AAZA CA  1 
ATOM   1507 C C   . THR A 1 236 ? 42.04300 14.78100 42.08800  1.000 82.51000  ?  778  THR AAZA C   1 
ATOM   1508 O O   . THR A 1 236 ? 42.05300 13.54600 42.08800  1.000 84.77000  ?  778  THR AAZA O   1 
ATOM   1509 C CB  . THR A 1 236 ? 43.21900 15.52400 40.00900  1.000 81.87000  ?  778  THR AAZA CB  1 
ATOM   1510 O OG1 . THR A 1 236 ? 44.28900 15.76600 40.91900  1.000 81.71000  ?  778  THR AAZA OG1 1 
ATOM   1511 C CG2 . THR A 1 236 ? 43.23500 16.58500 38.92000  1.000 81.36000  ?  778  THR AAZA CG2 1 
ATOM   1512 N N   . LEU A 1 237 ? 42.18000 15.47600 43.21000  1.000 80.02000  ?  779  LEU AAZA N   1 
ATOM   1513 C CA  . LEU A 1 237 ? 42.11500 14.73300 44.45500  1.000 82.17000  ?  779  LEU AAZA CA  1 
ATOM   1514 C C   . LEU A 1 237 ? 40.66500 14.39600 44.77600  1.000 81.62000  ?  779  LEU AAZA C   1 
ATOM   1515 O O   . LEU A 1 237 ? 39.72600 14.97000 44.21700  1.000 78.90000  ?  779  LEU AAZA O   1 
ATOM   1516 C CB  . LEU A 1 237 ? 42.75300 15.51900 45.59400  1.000 82.13000  ?  779  LEU AAZA CB  1 
ATOM   1517 C CG  . LEU A 1 237 ? 44.27600 15.53500 45.51400  1.000 84.24000  ?  779  LEU AAZA CG  1 
ATOM   1518 C CD1 . LEU A 1 237 ? 44.84800 16.66400 46.30400  1.000 78.37000  ?  779  LEU AAZA CD1 1 
ATOM   1519 C CD2 . LEU A 1 237 ? 44.81600 14.21900 46.02500  1.000 90.47000  ?  779  LEU AAZA CD2 1 
ATOM   1520 N N   . HIS A 1 238 ? 40.48000 13.44500 45.66500  1.000 80.00000  ?  780  HIS AAZA N   1 
ATOM   1521 C CA  . HIS A 1 238 ? 39.11800 13.07300 45.99100  1.000 84.26000  ?  780  HIS AAZA CA  1 
ATOM   1522 C C   . HIS A 1 238 ? 38.51000 14.10600 46.93000  1.000 85.16000  ?  780  HIS AAZA C   1 
ATOM   1523 O O   . HIS A 1 238 ? 39.06100 14.34600 48.01200  1.000 84.28000  ?  780  HIS AAZA O   1 
ATOM   1524 C CB  . HIS A 1 238 ? 39.04300 11.68700 46.60800  1.000 87.89000  ?  780  HIS AAZA CB  1 
ATOM   1525 C CG  . HIS A 1 238 ? 37.66600 11.10000 46.55200  1.000 90.00000  ?  780  HIS AAZA CG  1 
ATOM   1526 N ND1 . HIS A 1 238 ? 36.63800 11.54400 47.35500  1.000 89.11000  ?  780  HIS AAZA ND1 1 
ATOM   1527 C CD2 . HIS A 1 238 ? 37.13000 10.15400 45.74600  1.000 94.57000  ?  780  HIS AAZA CD2 1 
ATOM   1528 C CE1 . HIS A 1 238 ? 35.53700 10.87200 47.07200  1.000 91.74000  ?  780  HIS AAZA CE1 1 
ATOM   1529 N NE2 . HIS A 1 238 ? 35.80700 10.02600 46.09600  1.000 95.53000  ?  780  HIS AAZA NE2 1 
ATOM   1530 N N   . PRO A 1 239 ? 37.38000 14.72500 46.56300  1.000 84.23000  ?  781  PRO AAZA N   1 
ATOM   1531 C CA  . PRO A 1 239 ? 36.76400 15.73700 47.44000  1.000 82.60000  ?  781  PRO AAZA CA  1 
ATOM   1532 C C   . PRO A 1 239 ? 36.61500 15.30700 48.88600  1.000 82.39000  ?  781  PRO AAZA C   1 
ATOM   1533 O O   . PRO A 1 239 ? 36.84400 16.12800 49.77500  1.000 84.57000  ?  781  PRO AAZA O   1 
ATOM   1534 C CB  . PRO A 1 239 ? 35.39600 15.98500 46.77600  1.000 82.03000  ?  781  PRO AAZA CB  1 
ATOM   1535 C CG  . PRO A 1 239 ? 35.20800 14.87000 45.79400  1.000 81.32000  ?  781  PRO AAZA CG  1 
ATOM   1536 C CD  . PRO A 1 239 ? 36.58800 14.51000 45.34700  1.000 83.98000  ?  781  PRO AAZA CD  1 
ATOM   1537 N N   . ILE A 1 240 ? 36.24500 14.05500 49.15500  1.000 81.44000  ?  782  ILE AAZA N   1 
ATOM   1538 C CA  . ILE A 1 240 ? 36.15900 13.60300 50.53700  1.000 80.21000  ?  782  ILE AAZA CA  1 
ATOM   1539 C C   . ILE A 1 240 ? 37.52500 13.64100 51.18900  1.000 82.40000  ?  782  ILE AAZA C   1 
ATOM   1540 O O   . ILE A 1 240 ? 37.64900 13.95300 52.37700  1.000 85.58000  ?  782  ILE AAZA O   1 
ATOM   1541 C CB  . ILE A 1 240 ? 35.56200 12.19100 50.62200  1.000 87.81000  ?  782  ILE AAZA CB  1 
ATOM   1542 C CG1 . ILE A 1 240 ? 34.07000 12.21600 50.31900  1.000 92.84000  ?  782  ILE AAZA CG1 1 
ATOM   1543 C CG2 . ILE A 1 240 ? 35.83400 11.57800 51.99600  1.000 86.12000  ?  782  ILE AAZA CG2 1 
ATOM   1544 C CD1 . ILE A 1 240 ? 33.42900 10.88300 50.49300  1.000 96.07000  ?  782  ILE AAZA CD1 1 
ATOM   1545 N N   . GLU A 1 241 ? 38.57300 13.31300 50.44200  1.000 77.90000  ?  783  GLU AAZA N   1 
ATOM   1546 C CA  . GLU A 1 241 ? 39.85700 13.27900 51.11800  1.000 81.60000  ?  783  GLU AAZA CA  1 
ATOM   1547 C C   . GLU A 1 241 ? 40.45900 14.66100 51.27000  1.000 82.34000  ?  783  GLU AAZA C   1 
ATOM   1548 O O   . GLU A 1 241 ? 41.30400 14.86600 52.14700  1.000 83.36000  ?  783  GLU AAZA O   1 
ATOM   1549 C CB  . GLU A 1 241 ? 40.83500 12.34200 50.41600  1.000 78.78000  ?  783  GLU AAZA CB  1 
ATOM   1550 C CG  . GLU A 1 241 ? 41.79100 11.69400 51.41200  1.000 81.70000  ?  783  GLU AAZA CG  1 
ATOM   1551 C CD  . GLU A 1 241 ? 41.05700 11.02800 52.60400  1.000 92.51000  ?  783  GLU AAZA CD  1 
ATOM   1552 O OE1 . GLU A 1 241 ? 39.94700 10.46700 52.39500  1.000 94.10000  ?  783  GLU AAZA OE1 1 
ATOM   1553 O OE2 . GLU A 1 241 ? 41.58000 11.07900 53.75400  1.000 85.20000  ?  783  GLU AAZA OE2 1 
ATOM   1554 N N   . ILE A 1 242 ? 40.01900 15.62200 50.46500  1.000 83.90000  ?  784  ILE AAZA N   1 
ATOM   1555 C CA  . ILE A 1 242 ? 40.43500 17.00600 50.67400  1.000 82.21000  ?  784  ILE AAZA CA  1 
ATOM   1556 C C   . ILE A 1 242 ? 39.89700 17.52800 52.00000  1.000 77.44000  ?  784  ILE AAZA C   1 
ATOM   1557 O O   . ILE A 1 242 ? 40.65500 17.99400 52.85500  1.000 78.95000  ?  784  ILE AAZA O   1 
ATOM   1558 C CB  . ILE A 1 242 ? 39.99400 17.88100 49.49000  1.000 78.22000  ?  784  ILE AAZA CB  1 
ATOM   1559 C CG1 . ILE A 1 242 ? 40.53800 17.27900 48.19400  1.000 75.84000  ?  784  ILE AAZA CG1 1 
ATOM   1560 C CG2 . ILE A 1 242 ? 40.40500 19.29900 49.71700  1.000 76.36000  ?  784  ILE AAZA CG2 1 
ATOM   1561 C CD1 . ILE A 1 242 ? 40.69700 18.25700 47.10000  1.000 78.19000  ?  784  ILE AAZA CD1 1 
ATOM   1562 N N   . ALA A 1 243 ? 38.58400 17.44100 52.19500  1.000 74.78000  ?  785  ALA AAZA N   1 
ATOM   1563 C CA  . ALA A 1 243 ? 37.99500 17.94400 53.42500  1.000 75.36000  ?  785  ALA AAZA CA  1 
ATOM   1564 C C   . ALA A 1 243 ? 38.54800 17.20900 54.63700  1.000 80.11000  ?  785  ALA AAZA C   1 
ATOM   1565 O O   . ALA A 1 243 ? 38.82100 17.83100 55.66700  1.000 78.60000  ?  785  ALA AAZA O   1 
ATOM   1566 C CB  . ALA A 1 243 ? 36.47400 17.83100 53.36500  1.000 75.91000  ?  785  ALA AAZA CB  1 
ATOM   1567 N N   . ARG A 1 244 ? 38.74400 15.89000 54.52800  1.000 83.64000  ?  786  ARG AAZA N   1 
ATOM   1568 C CA  . ARG A 1 244 ? 39.36500 15.13300 55.61700  1.000 84.40000  ?  786  ARG AAZA CA  1 
ATOM   1569 C C   . ARG A 1 244 ? 40.74500 15.68700 55.95700  1.000 81.76000  ?  786  ARG AAZA C   1 
ATOM   1570 O O   . ARG A 1 244 ? 41.04500 15.99400 57.11800  1.000 73.85000  ?  786  ARG AAZA O   1 
ATOM   1571 C CB  . ARG A 1 244 ? 39.45000 13.65000 55.24100  1.000 83.74000  ?  786  ARG AAZA CB  1 
ATOM   1572 C CG  . ARG A 1 244 ? 38.13800 12.89700 55.41800  1.000 91.95000  ?  786  ARG AAZA CG  1 
ATOM   1573 C CD  . ARG A 1 244 ? 38.17700 11.51300 54.78200  1.000 96.39000  ?  786  ARG AAZA CD  1 
ATOM   1574 N NE  . ARG A 1 244 ? 37.05300 10.66800 55.18100  1.000 103.61000 ?  786  ARG AAZA NE  1 
ATOM   1575 C CZ  . ARG A 1 244 ? 36.78800 9.48200  54.64600  1.000 105.77000 ?  786  ARG AAZA CZ  1 
ATOM   1576 N NH1 . ARG A 1 244 ? 37.47700 9.02300  53.61100  1.000 98.86000  ?  786  ARG AAZA NH1 1 
ATOM   1577 N NH2 . ARG A 1 244 ? 35.79100 8.75000  55.14400  1.000 105.59000 ?  786  ARG AAZA NH2 1 
ATOM   1578 N N   . GLN A 1 245 ? 41.59300 15.84400 54.94500  1.000 83.04000  ?  787  GLN AAZA N   1 
ATOM   1579 C CA  . GLN A 1 245 ? 42.96500 16.25000 55.20500  1.000 82.49000  ?  787  GLN AAZA CA  1 
ATOM   1580 C C   . GLN A 1 245 ? 43.03700 17.69400 55.69400  1.000 80.79000  ?  787  GLN AAZA C   1 
ATOM   1581 O O   . GLN A 1 245 ? 43.78000 17.99900 56.63500  1.000 78.29000  ?  787  GLN AAZA O   1 
ATOM   1582 C CB  . GLN A 1 245 ? 43.81000 16.02800 53.95200  1.000 81.68000  ?  787  GLN AAZA CB  1 
ATOM   1583 C CG  . GLN A 1 245 ? 43.92800 14.54800 53.57200  1.000 83.56000  ?  787  GLN AAZA CG  1 
ATOM   1584 C CD  . GLN A 1 245 ? 44.53500 13.69700 54.68200  1.000 89.21000  ?  787  GLN AAZA CD  1 
ATOM   1585 O OE1 . GLN A 1 245 ? 45.36400 14.18100 55.45300  1.000 92.37000  ?  787  GLN AAZA OE1 1 
ATOM   1586 N NE2 . GLN A 1 245 ? 44.14800 12.41900 54.75000  1.000 85.04000  ?  787  GLN AAZA NE2 1 
ATOM   1587 N N   . LEU A 1 246 ? 42.27300 18.60200 55.07500  1.000 82.03000  ?  788  LEU AAZA N   1 
ATOM   1588 C CA  . LEU A 1 246 ? 42.26000 19.98000 55.56300  1.000 79.71000  ?  788  LEU AAZA CA  1 
ATOM   1589 C C   . LEU A 1 246 ? 41.81600 20.00900 57.01000  1.000 79.50000  ?  788  LEU AAZA C   1 
ATOM   1590 O O   . LEU A 1 246 ? 42.58400 20.40800 57.89400  1.000 80.12000  ?  788  LEU AAZA O   1 
ATOM   1591 C CB  . LEU A 1 246 ? 41.35600 20.86800 54.71000  1.000 76.52000  ?  788  LEU AAZA CB  1 
ATOM   1592 C CG  . LEU A 1 246 ? 41.82800 21.09900 53.27900  1.000 75.40000  ?  788  LEU AAZA CG  1 
ATOM   1593 C CD1 . LEU A 1 246 ? 40.77500 21.87900 52.54200  1.000 77.30000  ?  788  LEU AAZA CD1 1 
ATOM   1594 C CD2 . LEU A 1 246 ? 43.17100 21.76800 53.21900  1.000 70.19000  ?  788  LEU AAZA CD2 1 
ATOM   1595 N N   . THR A 1 247 ? 40.58900 19.53000 57.27000  1.000 78.81000  ?  789  THR AAZA N   1 
ATOM   1596 C CA  . THR A 1 247 ? 40.03500 19.34500 58.61400  1.000 77.46000  ?  789  THR AAZA CA  1 
ATOM   1597 C C   . THR A 1 247 ? 41.06000 18.75600 59.56600  1.000 73.82000  ?  789  THR AAZA C   1 
ATOM   1598 O O   . THR A 1 247 ? 41.16000 19.19400 60.70700  1.000 72.86000  ?  789  THR AAZA O   1 
ATOM   1599 C CB  . THR A 1 247 ? 38.82000 18.42000 58.58100  1.000 77.81000  ?  789  THR AAZA CB  1 
ATOM   1600 O OG1 . THR A 1 247 ? 37.68100 19.12200 58.07000  1.000 79.25000  ?  789  THR AAZA OG1 1 
ATOM   1601 C CG2 . THR A 1 247 ? 38.52100 17.86400 59.95700  1.000 72.13000  ?  789  THR AAZA CG2 1 
ATOM   1602 N N   . LEU A 1 248 ? 41.83400 17.77600 59.09600  1.000 77.78000  ?  790  LEU AAZA N   1 
ATOM   1603 C CA  . LEU A 1 248 ? 42.85600 17.17000 59.94200  1.000 77.58000  ?  790  LEU AAZA CA  1 
ATOM   1604 C C   . LEU A 1 248 ? 43.88400 18.19800 60.37900  1.000 75.14000  ?  790  LEU AAZA C   1 
ATOM   1605 O O   . LEU A 1 248 ? 44.10900 18.39400 61.57500  1.000 78.58000  ?  790  LEU AAZA O   1 
ATOM   1606 C CB  . LEU A 1 248 ? 43.54700 16.01400 59.22200  1.000 78.77000  ?  790  LEU AAZA CB  1 
ATOM   1607 C CG  . LEU A 1 248 ? 43.09800 14.59700 59.61200  1.000 80.83000  ?  790  LEU AAZA CG  1 
ATOM   1608 C CD1 . LEU A 1 248 ? 44.12600 13.62100 59.11900  1.000 87.57000  ?  790  LEU AAZA CD1 1 
ATOM   1609 C CD2 . LEU A 1 248 ? 42.76200 14.36400 61.09800  1.000 79.13000  ?  790  LEU AAZA CD2 1 
ATOM   1610 N N   . LEU A 1 249 ? 44.52400 18.87000 59.43200  1.000 75.66000  ?  791  LEU AAZA N   1 
ATOM   1611 C CA  . LEU A 1 249 ? 45.50000 19.86800 59.84800  1.000 78.40000  ?  791  LEU AAZA CA  1 
ATOM   1612 C C   . LEU A 1 249 ? 44.85600 21.13600 60.42000  1.000 79.40000  ?  791  LEU AAZA C   1 
ATOM   1613 O O   . LEU A 1 249 ? 45.42400 21.75100 61.33000  1.000 79.53000  ?  791  LEU AAZA O   1 
ATOM   1614 C CB  . LEU A 1 249 ? 46.46900 20.14800 58.69700  1.000 74.18000  ?  791  LEU AAZA CB  1 
ATOM   1615 C CG  . LEU A 1 249 ? 46.05000 20.62500 57.32300  1.000 72.91000  ?  791  LEU AAZA CG  1 
ATOM   1616 C CD1 . LEU A 1 249 ? 45.83600 22.07800 57.34200  1.000 85.36000  ?  791  LEU AAZA CD1 1 
ATOM   1617 C CD2 . LEU A 1 249 ? 47.23900 20.35500 56.45000  1.000 69.18000  ?  791  LEU AAZA CD2 1 
ATOM   1618 N N   . GLU A 1 250 ? 43.65700 21.50800 59.96800  1.000 78.80000  ?  792  GLU AAZA N   1 
ATOM   1619 C CA  . GLU A 1 250 ? 42.97100 22.65400 60.56000  1.000 74.09000  ?  792  GLU AAZA CA  1 
ATOM   1620 C C   . GLU A 1 250 ? 42.68900 22.43900 62.04200  1.000 76.46000  ?  792  GLU AAZA C   1 
ATOM   1621 O O   . GLU A 1 250 ? 42.80100 23.37500 62.84400  1.000 76.84000  ?  792  GLU AAZA O   1 
ATOM   1622 C CB  . GLU A 1 250 ? 41.68800 22.93700 59.78500  1.000 70.71000  ?  792  GLU AAZA CB  1 
ATOM   1623 C CG  . GLU A 1 250 ? 42.04500 23.46000 58.41900  1.000 80.34000  ?  792  GLU AAZA CG  1 
ATOM   1624 C CD  . GLU A 1 250 ? 40.92100 24.17400 57.69900  1.000 85.29000  ?  792  GLU AAZA CD  1 
ATOM   1625 O OE1 . GLU A 1 250 ? 39.97000 24.66000 58.37900  1.000 79.31000  ?  792  GLU AAZA OE1 1 
ATOM   1626 O OE2 . GLU A 1 250 ? 41.03100 24.26000 56.44000  1.000 85.07000  ?  792  GLU AAZA OE2 1 
ATOM   1627 N N   . SER A 1 251 ? 42.30600 21.21600 62.42100  1.000 79.26000  ?  793  SER AAZA N   1 
ATOM   1628 C CA  . SER A 1 251 ? 42.11700 20.89000 63.83100  1.000 76.24000  ?  793  SER AAZA CA  1 
ATOM   1629 C C   . SER A 1 251 ? 43.42900 20.97500 64.57700  1.000 79.11000  ?  793  SER AAZA C   1 
ATOM   1630 O O   . SER A 1 251 ? 43.49400 21.52300 65.68200  1.000 79.08000  ?  793  SER AAZA O   1 
ATOM   1631 C CB  . SER A 1 251 ? 41.52900 19.49100 63.98300  1.000 74.90000  ?  793  SER AAZA CB  1 
ATOM   1632 O OG  . SER A 1 251 ? 41.47100 19.12300 65.34300  1.000 80.61000  ?  793  SER AAZA OG  1 
ATOM   1633 N N   . ASP A 1 252 ? 44.48900 20.44600 63.98100  1.000 79.92000  ?  794  ASP AAZA N   1 
ATOM   1634 C CA  . ASP A 1 252 ? 45.77300 20.48500 64.65500  1.000 84.06000  ?  794  ASP AAZA CA  1 
ATOM   1635 C C   . ASP A 1 252 ? 46.27100 21.91300 64.81700  1.000 78.68000  ?  794  ASP AAZA C   1 
ATOM   1636 O O   . ASP A 1 252 ? 46.89500 22.23600 65.83100  1.000 74.98000  ?  794  ASP AAZA O   1 
ATOM   1637 C CB  . ASP A 1 252 ? 46.76300 19.60200 63.89900  1.000 86.04000  ?  794  ASP AAZA CB  1 
ATOM   1638 C CG  . ASP A 1 252 ? 46.63100 18.12800 64.29400  1.000 95.70000  ?  794  ASP AAZA CG  1 
ATOM   1639 O OD1 . ASP A 1 252 ? 45.69900 17.78700 65.07400  1.000 94.08000  ?  794  ASP AAZA OD1 1 
ATOM   1640 O OD2 . ASP A 1 252 ? 47.45700 17.31100 63.82700  1.000 106.51000 ?  794  ASP AAZA OD2 1 
ATOM   1641 N N   . LEU A 1 253 ? 45.96700 22.78700 63.85500  1.000 78.33000  ?  795  LEU AAZA N   1 
ATOM   1642 C CA  . LEU A 1 253 ? 46.26400 24.20700 64.01600  1.000 75.19000  ?  795  LEU AAZA CA  1 
ATOM   1643 C C   . LEU A 1 253 ? 45.47200 24.80500 65.17200  1.000 77.07000  ?  795  LEU AAZA C   1 
ATOM   1644 O O   . LEU A 1 253 ? 46.01300 25.54700 66.00400  1.000 74.03000  ?  795  LEU AAZA O   1 
ATOM   1645 C CB  . LEU A 1 253 ? 45.93900 24.94100 62.72800  1.000 67.61000  ?  795  LEU AAZA CB  1 
ATOM   1646 C CG  . LEU A 1 253 ? 47.11200 24.86500 61.78800  1.000 67.44000  ?  795  LEU AAZA CG  1 
ATOM   1647 C CD1 . LEU A 1 253 ? 46.73600 25.53300 60.51500  1.000 72.22000  ?  795  LEU AAZA CD1 1 
ATOM   1648 C CD2 . LEU A 1 253 ? 48.29000 25.52800 62.41900  1.000 72.32000  ?  795  LEU AAZA CD2 1 
ATOM   1649 N N   . TYR A 1 254 ? 44.17200 24.49900 65.21800  1.000 78.21000  ?  796  TYR AAZA N   1 
ATOM   1650 C CA  . TYR A 1 254 ? 43.30200 25.02100 66.25800  1.000 73.77000  ?  796  TYR AAZA CA  1 
ATOM   1651 C C   . TYR A 1 254 ? 43.76900 24.59600 67.63600  1.000 76.35000  ?  796  TYR AAZA C   1 
ATOM   1652 O O   . TYR A 1 254 ? 43.79500 25.40500 68.56800  1.000 77.73000  ?  796  TYR AAZA O   1 
ATOM   1653 C CB  . TYR A 1 254 ? 41.89300 24.52800 66.02300  1.000 70.29000  ?  796  TYR AAZA CB  1 
ATOM   1654 C CG  . TYR A 1 254 ? 41.01200 24.79400 67.18900  1.000 69.88000  ?  796  TYR AAZA CG  1 
ATOM   1655 C CD1 . TYR A 1 254 ? 40.54000 26.06400 67.43000  1.000 68.69000  ?  796  TYR AAZA CD1 1 
ATOM   1656 C CD2 . TYR A 1 254 ? 40.63500 23.78200 68.03500  1.000 71.13000  ?  796  TYR AAZA CD2 1 
ATOM   1657 C CE1 . TYR A 1 254 ? 39.72900 26.32100 68.47000  1.000 67.48000  ?  796  TYR AAZA CE1 1 
ATOM   1658 C CE2 . TYR A 1 254 ? 39.80700 24.02700 69.08800  1.000 72.16000  ?  796  TYR AAZA CE2 1 
ATOM   1659 C CZ  . TYR A 1 254 ? 39.36200 25.30000 69.30700  1.000 74.41000  ?  796  TYR AAZA CZ  1 
ATOM   1660 O OH  . TYR A 1 254 ? 38.53000 25.55200 70.37500  1.000 79.68000  ?  796  TYR AAZA OH  1 
ATOM   1661 N N   . ARG A 1 255 ? 44.13900 23.32600 67.78300  1.000 77.94000  ?  797  ARG AAZA N   1 
ATOM   1662 C CA  . ARG A 1 255 ? 44.51200 22.80000 69.08300  1.000 72.74000  ?  797  ARG AAZA CA  1 
ATOM   1663 C C   . ARG A 1 255 ? 45.81300 23.39200 69.60000  1.000 73.21000  ?  797  ARG AAZA C   1 
ATOM   1664 O O   . ARG A 1 255 ? 46.06500 23.33300 70.80500  1.000 80.11000  ?  797  ARG AAZA O   1 
ATOM   1665 C CB  . ARG A 1 255 ? 44.60400 21.27600 69.01500  1.000 74.97000  ?  797  ARG AAZA CB  1 
ATOM   1666 C CG  . ARG A 1 255 ? 43.24200 20.59400 68.77200  1.000 81.42000  ?  797  ARG AAZA CG  1 
ATOM   1667 C CD  . ARG A 1 255 ? 43.36300 19.10800 68.41400  1.000 85.00000  ?  797  ARG AAZA CD  1 
ATOM   1668 N NE  . ARG A 1 255 ? 43.71200 18.29800 69.58000  1.000 93.57000  ?  797  ARG AAZA NE  1 
ATOM   1669 C CZ  . ARG A 1 255 ? 44.10800 17.03200 69.53500  1.000 94.31000  ?  797  ARG AAZA CZ  1 
ATOM   1670 N NH1 . ARG A 1 255 ? 44.21200 16.38400 68.39000  1.000 99.47000  ?  797  ARG AAZA NH1 1 
ATOM   1671 N NH2 . ARG A 1 255 ? 44.43100 16.41000 70.66600  1.000 95.68000  ?  797  ARG AAZA NH2 1 
ATOM   1672 N N   . ALA A 1 256 ? 46.63600 23.97700 68.73600  1.000 70.61000  ?  798  ALA AAZA N   1 
ATOM   1673 C CA  . ALA A 1 256 ? 47.94000 24.47000 69.16000  1.000 68.69000  ?  798  ALA AAZA CA  1 
ATOM   1674 C C   . ALA A 1 256 ? 47.86800 25.78300 69.91200  1.000 74.87000  ?  798  ALA AAZA C   1 
ATOM   1675 O O   . ALA A 1 256 ? 48.88900 26.22800 70.44600  1.000 76.92000  ?  798  ALA AAZA O   1 
ATOM   1676 C CB  . ALA A 1 256 ? 48.85700 24.65800 67.95300  1.000 72.92000  ?  798  ALA AAZA CB  1 
ATOM   1677 N N   . VAL A 1 257 ? 46.70700 26.42500 69.95300  1.000 74.80000  ?  799  VAL AAZA N   1 
ATOM   1678 C CA  . VAL A 1 257 ? 46.62300 27.78400 70.46500  1.000 72.45000  ?  799  VAL AAZA CA  1 
ATOM   1679 C C   . VAL A 1 257 ? 46.55100 27.71500 71.98400  1.000 81.81000  ?  799  VAL AAZA C   1 
ATOM   1680 O O   . VAL A 1 257 ? 45.59500 27.17900 72.55300  1.000 84.19000  ?  799  VAL AAZA O   1 
ATOM   1681 C CB  . VAL A 1 257 ? 45.43000 28.53100 69.87400  1.000 71.41000  ?  799  VAL AAZA CB  1 
ATOM   1682 C CG1 . VAL A 1 257 ? 45.64500 30.01500 70.00400  1.000 70.42000  ?  799  VAL AAZA CG1 1 
ATOM   1683 C CG2 . VAL A 1 257 ? 45.28800 28.16900 68.41500  1.000 73.52000  ?  799  VAL AAZA CG2 1 
ATOM   1684 N N   . GLN A 1 258 ? 47.57900 28.24200 72.64200  1.000 83.55000  ?  800  GLN AAZA N   1 
ATOM   1685 C CA  . GLN A 1 258 ? 47.71500 28.34200 74.08400  1.000 79.89000  ?  800  GLN AAZA CA  1 
ATOM   1686 C C   . GLN A 1 258 ? 47.11000 29.65400 74.57200  1.000 76.00000  ?  800  GLN AAZA C   1 
ATOM   1687 O O   . GLN A 1 258 ? 47.23800 30.68300 73.89400  1.000 70.95000  ?  800  GLN AAZA O   1 
ATOM   1688 C CB  . GLN A 1 258 ? 49.18600 28.26300 74.47800  1.000 81.88000  ?  800  GLN AAZA CB  1 
ATOM   1689 C CG  . GLN A 1 258 ? 49.70300 26.85200 74.36600  1.000 88.50000  ?  800  GLN AAZA CG  1 
ATOM   1690 C CD  . GLN A 1 258 ? 48.77500 25.85800 75.04700  1.000 92.22000  ?  800  GLN AAZA CD  1 
ATOM   1691 O OE1 . GLN A 1 258 ? 48.63600 25.85500 76.28600  1.000 90.73000  ?  800  GLN AAZA OE1 1 
ATOM   1692 N NE2 . GLN A 1 258 ? 48.08800 25.04500 74.23800  1.000 84.45000  ?  800  GLN AAZA NE2 1 
ATOM   1693 N N   . PRO A 1 259 ? 46.43900 29.63900 75.73400  1.000 76.01000  ?  801  PRO AAZA N   1 
ATOM   1694 C CA  . PRO A 1 259 ? 45.80800 30.86800 76.23200  1.000 68.28000  ?  801  PRO AAZA CA  1 
ATOM   1695 C C   . PRO A 1 259 ? 46.80600 31.95100 76.56100  1.000 66.21000  ?  801  PRO AAZA C   1 
ATOM   1696 O O   . PRO A 1 259 ? 46.40100 33.10700 76.76700  1.000 60.73000  ?  801  PRO AAZA O   1 
ATOM   1697 C CB  . PRO A 1 259 ? 45.05900 30.39900 77.48100  1.000 60.87000  ?  801  PRO AAZA CB  1 
ATOM   1698 C CG  . PRO A 1 259 ? 44.97000 28.92900 77.36500  1.000 67.00000  ?  801  PRO AAZA CG  1 
ATOM   1699 C CD  . PRO A 1 259 ? 46.22500 28.52100 76.66200  1.000 76.24000  ?  801  PRO AAZA CD  1 
ATOM   1700 N N   . SER A 1 260 ? 48.09900 31.62600 76.60600  1.000 65.68000  ?  802  SER AAZA N   1 
ATOM   1701 C CA  . SER A 1 260 ? 49.07300 32.69100 76.74900  1.000 64.05000  ?  802  SER AAZA CA  1 
ATOM   1702 C C   . SER A 1 260 ? 48.98900 33.65500 75.57900  1.000 65.86000  ?  802  SER AAZA C   1 
ATOM   1703 O O   . SER A 1 260 ? 49.28700 34.84600 75.74600  1.000 65.06000  ?  802  SER AAZA O   1 
ATOM   1704 C CB  . SER A 1 260 ? 50.47400 32.11200 76.89800  1.000 62.51000  ?  802  SER AAZA CB  1 
ATOM   1705 O OG  . SER A 1 260 ? 50.99000 31.63700 75.68500  1.000 71.05000  ?  802  SER AAZA OG  1 
ATOM   1706 N N   . GLU A 1 261 ? 48.51400 33.16700 74.41000  1.000 67.60000  ?  803  GLU AAZA N   1 
ATOM   1707 C CA  . GLU A 1 261 ? 48.44400 33.90500 73.15000  1.000 64.15000  ?  803  GLU AAZA CA  1 
ATOM   1708 C C   . GLU A 1 261 ? 47.18300 34.74000 72.98000  1.000 63.65000  ?  803  GLU AAZA C   1 
ATOM   1709 O O   . GLU A 1 261 ? 47.11100 35.51900 72.02800  1.000 65.55000  ?  803  GLU AAZA O   1 
ATOM   1710 C CB  . GLU A 1 261 ? 48.51400 32.95900 71.95200  1.000 65.67000  ?  803  GLU AAZA CB  1 
ATOM   1711 C CG  . GLU A 1 261 ? 49.47200 31.77700 72.05700  1.000 76.42000  ?  803  GLU AAZA CG  1 
ATOM   1712 C CD  . GLU A 1 261 ? 49.79000 31.15800 70.66200  1.000 84.60000  ?  803  GLU AAZA CD  1 
ATOM   1713 O OE1 . GLU A 1 261 ? 49.49000 31.83100 69.64400  1.000 80.82000  ?  803  GLU AAZA OE1 1 
ATOM   1714 O OE2 . GLU A 1 261 ? 50.33200 30.01800 70.57400  1.000 86.81000  ?  803  GLU AAZA OE2 1 
ATOM   1715 N N   . LEU A 1 262 ? 46.17200 34.56700 73.82800  1.000 64.71000  ?  804  LEU AAZA N   1 
ATOM   1716 C CA  . LEU A 1 262 ? 44.92900 35.32600 73.74100  1.000 63.64000  ?  804  LEU AAZA CA  1 
ATOM   1717 C C   . LEU A 1 262 ? 44.77600 36.35400 74.84700  1.000 62.14000  ?  804  LEU AAZA C   1 
ATOM   1718 O O   . LEU A 1 262 ? 44.39800 37.49800 74.58900  1.000 61.27000  ?  804  LEU AAZA O   1 
ATOM   1719 C CB  . LEU A 1 262 ? 43.72600 34.37900 73.77800  1.000 56.63000  ?  804  LEU AAZA CB  1 
ATOM   1720 C CG  . LEU A 1 262 ? 43.91500 33.22800 72.83200  1.000 57.26000  ?  804  LEU AAZA CG  1 
ATOM   1721 C CD1 . LEU A 1 262 ? 42.73400 32.37900 72.93500  1.000 62.27000  ?  804  LEU AAZA CD1 1 
ATOM   1722 C CD2 . LEU A 1 262 ? 44.00200 33.80700 71.45600  1.000 61.81000  ?  804  LEU AAZA CD2 1 
ATOM   1723 N N   . VAL A 1 263 ? 45.02700 35.94800 76.08900  1.000 66.73000  ?  805  VAL AAZA N   1 
ATOM   1724 C CA  . VAL A 1 263 ? 44.77900 36.82900 77.21500  1.000 63.12000  ?  805  VAL AAZA CA  1 
ATOM   1725 C C   . VAL A 1 263 ? 45.64100 38.06500 77.08700  1.000 63.17000  ?  805  VAL AAZA C   1 
ATOM   1726 O O   . VAL A 1 263 ? 46.85800 37.97800 76.87200  1.000 63.83000  ?  805  VAL AAZA O   1 
ATOM   1727 C CB  . VAL A 1 263 ? 45.01600 36.08000 78.52500  1.000 58.90000  ?  805  VAL AAZA CB  1 
ATOM   1728 C CG1 . VAL A 1 263 ? 44.84700 37.02700 79.64700  1.000 66.89000  ?  805  VAL AAZA CG1 1 
ATOM   1729 C CG2 . VAL A 1 263 ? 43.99700 34.97000 78.64000  1.000 55.33000  ?  805  VAL AAZA CG2 1 
ATOM   1730 N N   . GLY A 1 264 ? 45.00400 39.22200 77.18900  1.000 57.74000  ?  806  GLY AAZA N   1 
ATOM   1731 C CA  . GLY A 1 264 ? 45.68900 40.47200 76.98600  1.000 63.21000  ?  806  GLY AAZA CA  1 
ATOM   1732 C C   . GLY A 1 264 ? 45.63300 41.00400 75.57800  1.000 65.06000  ?  806  GLY AAZA C   1 
ATOM   1733 O O   . GLY A 1 264 ? 46.41200 41.90700 75.24400  1.000 66.35000  ?  806  GLY AAZA O   1 
ATOM   1734 N N   . SER A 1 265 ? 44.74500 40.46300 74.73800  1.000 66.40000  ?  807  SER AAZA N   1 
ATOM   1735 C CA  . SER A 1 265 ? 44.60900 40.82800 73.31700  1.000 66.76000  ?  807  SER AAZA CA  1 
ATOM   1736 C C   . SER A 1 265 ? 45.94500 40.86000 72.57800  1.000 64.74000  ?  807  SER AAZA C   1 
ATOM   1737 O O   . SER A 1 265 ? 46.07700 41.52400 71.55500  1.000 64.95000  ?  807  SER AAZA O   1 
ATOM   1738 C CB  . SER A 1 265 ? 43.89300 42.16600 73.15400  1.000 66.23000  ?  807  SER AAZA CB  1 
ATOM   1739 O OG  . SER A 1 265 ? 42.55600 42.05100 73.61000  1.000 77.08000  ?  807  SER AAZA OG  1 
ATOM   1740 N N   . VAL A 1 266 ? 46.93800 40.11400 73.06000  1.000 65.90000  ?  808  VAL AAZA N   1 
ATOM   1741 C CA  . VAL A 1 266 ? 48.31200 40.33200 72.65700  1.000 66.23000  ?  808  VAL AAZA CA  1 
ATOM   1742 C C   . VAL A 1 266 ? 48.55300 40.02000 71.18900  1.000 68.01000  ?  808  VAL AAZA C   1 
ATOM   1743 O O   . VAL A 1 266 ? 49.60900 40.37200 70.65400  1.000 70.78000  ?  808  VAL AAZA O   1 
ATOM   1744 C CB  . VAL A 1 266 ? 49.21600 39.51400 73.59600  1.000 61.08000  ?  808  VAL AAZA CB  1 
ATOM   1745 C CG1 . VAL A 1 266 ? 48.82400 39.84200 74.99200  1.000 60.32000  ?  808  VAL AAZA CG1 1 
ATOM   1746 C CG2 . VAL A 1 266 ? 49.04000 38.01900 73.35800  1.000 62.97000  ?  808  VAL AAZA CG2 1 
ATOM   1747 N N   . TRP A 1 267 ? 47.59600 39.38200 70.52200  1.000 62.15000  ?  809  TRP AAZA N   1 
ATOM   1748 C CA  . TRP A 1 267 ? 47.73700 39.14600 69.09700  1.000 63.75000  ?  809  TRP AAZA CA  1 
ATOM   1749 C C   . TRP A 1 267 ? 47.43400 40.38600 68.27400  1.000 63.97000  ?  809  TRP AAZA C   1 
ATOM   1750 O O   . TRP A 1 267 ? 47.52700 40.32100 67.04400  1.000 65.47000  ?  809  TRP AAZA O   1 
ATOM   1751 C CB  . TRP A 1 267 ? 46.83500 37.97900 68.66600  1.000 63.37000  ?  809  TRP AAZA CB  1 
ATOM   1752 C CG  . TRP A 1 267 ? 45.40300 38.34900 68.48600  1.000 60.75000  ?  809  TRP AAZA CG  1 
ATOM   1753 C CD1 . TRP A 1 267 ? 44.79600 38.71900 67.33800  1.000 57.68000  ?  809  TRP AAZA CD1 1 
ATOM   1754 C CD2 . TRP A 1 267 ? 44.39500 38.39600 69.50700  1.000 65.23000  ?  809  TRP AAZA CD2 1 
ATOM   1755 N NE1 . TRP A 1 267 ? 43.46100 38.99700 67.56200  1.000 56.54000  ?  809  TRP AAZA NE1 1 
ATOM   1756 C CE2 . TRP A 1 267 ? 43.18900 38.81100 68.88700  1.000 61.28000  ?  809  TRP AAZA CE2 1 
ATOM   1757 C CE3 . TRP A 1 267 ? 44.39000 38.12300 70.88100  1.000 59.23000  ?  809  TRP AAZA CE3 1 
ATOM   1758 C CZ2 . TRP A 1 267 ? 41.99500 38.95800 69.59100  1.000 60.28000  ?  809  TRP AAZA CZ2 1 
ATOM   1759 C CZ3 . TRP A 1 267 ? 43.19600 38.25800 71.57200  1.000 58.09000  ?  809  TRP AAZA CZ3 1 
ATOM   1760 C CH2 . TRP A 1 267 ? 42.02000 38.67800 70.93000  1.000 59.30000  ?  809  TRP AAZA CH2 1 
ATOM   1761 N N   . THR A 1 268 ? 47.08300 41.50900 68.91800  1.000 62.93000  ?  810  THR AAZA N   1 
ATOM   1762 C CA  . THR A 1 268 ? 46.70200 42.72700 68.21400  1.000 61.26000  ?  810  THR AAZA CA  1 
ATOM   1763 C C   . THR A 1 268 ? 47.69100 43.85700 68.47000  1.000 65.86000  ?  810  THR AAZA C   1 
ATOM   1764 O O   . THR A 1 268 ? 47.35700 45.03100 68.26100  1.000 65.41000  ?  810  THR AAZA O   1 
ATOM   1765 C CB  . THR A 1 268 ? 45.30200 43.20400 68.60600  1.000 57.04000  ?  810  THR AAZA CB  1 
ATOM   1766 O OG1 . THR A 1 268 ? 45.38700 43.98200 69.80300  1.000 59.42000  ?  810  THR AAZA OG1 1 
ATOM   1767 C CG2 . THR A 1 268 ? 44.36600 42.04000 68.83900  1.000 55.02000  ?  810  THR AAZA CG2 1 
ATOM   1768 N N   . LYS A 1 269 ? 48.90700 43.54200 68.90700  1.000 67.21000  ?  811  LYS AAZA N   1 
ATOM   1769 C CA  . LYS A 1 269 ? 49.88500 44.58500 69.17700  1.000 69.79000  ?  811  LYS AAZA CA  1 
ATOM   1770 C C   . LYS A 1 269 ? 51.28800 44.17500 68.74700  1.000 74.44000  ?  811  LYS AAZA C   1 
ATOM   1771 O O   . LYS A 1 269 ? 51.51500 43.07200 68.23400  1.000 75.13000  ?  811  LYS AAZA O   1 
ATOM   1772 C CB  . LYS A 1 269 ? 49.78500 45.00500 70.63400  1.000 63.07000  ?  811  LYS AAZA CB  1 
ATOM   1773 C CG  . LYS A 1 269 ? 49.56200 43.90100 71.59100  1.000 63.99000  ?  811  LYS AAZA CG  1 
ATOM   1774 C CD  . LYS A 1 269 ? 48.90200 44.60300 72.77000  1.000 69.70000  ?  811  LYS AAZA CD  1 
ATOM   1775 C CE  . LYS A 1 269 ? 47.60600 45.25600 72.27000  1.000 62.88000  ?  811  LYS AAZA CE  1 
ATOM   1776 N NZ  . LYS A 1 269 ? 46.90700 46.06500 73.27600  1.000 66.73000  ?  811  LYS AAZA NZ  1 
ATOM   1777 N N   . GLU A 1 270 ? 52.22200 45.11200 68.96600  1.000 75.86000  ?  812  GLU AAZA N   1 
ATOM   1778 C CA  . GLU A 1 270 ? 53.52800 45.11900 68.31100  1.000 78.00000  ?  812  GLU AAZA CA  1 
ATOM   1779 C C   . GLU A 1 270 ? 54.22400 43.76800 68.35200  1.000 80.58000  ?  812  GLU AAZA C   1 
ATOM   1780 O O   . GLU A 1 270 ? 54.89600 43.38000 67.38700  1.000 85.54000  ?  812  GLU AAZA O   1 
ATOM   1781 C CB  . GLU A 1 270 ? 54.41800 46.18100 68.95800  1.000 86.75000  ?  812  GLU AAZA CB  1 
ATOM   1782 C CG  . GLU A 1 270 ? 54.04400 47.62600 68.63500  1.000 88.75000  ?  812  GLU AAZA CG  1 
ATOM   1783 C CD  . GLU A 1 270 ? 55.21900 48.58900 68.81800  1.000 102.82000 ?  812  GLU AAZA CD  1 
ATOM   1784 O OE1 . GLU A 1 270 ? 56.14500 48.27300 69.61200  1.000 104.27000 ?  812  GLU AAZA OE1 1 
ATOM   1785 O OE2 . GLU A 1 270 ? 55.23400 49.64900 68.14900  1.000 110.65000 ?  812  GLU AAZA OE2 1 
ATOM   1786 N N   . ASP A 1 271 ? 54.08400 43.03100 69.45100  1.000 72.44000  ?  813  ASP AAZA N   1 
ATOM   1787 C CA  . ASP A 1 271 ? 54.76100 41.74200 69.55600  1.000 76.35000  ?  813  ASP AAZA CA  1 
ATOM   1788 C C   . ASP A 1 271 ? 53.89100 40.54400 69.29200  1.000 75.08000  ?  813  ASP AAZA C   1 
ATOM   1789 O O   . ASP A 1 271 ? 54.17300 39.45800 69.81000  1.000 73.20000  ?  813  ASP AAZA O   1 
ATOM   1790 C CB  . ASP A 1 271 ? 55.43600 41.62700 70.92900  1.000 83.15000  ?  813  ASP AAZA CB  1 
ATOM   1791 C CG  . ASP A 1 271 ? 56.53500 42.64900 71.13800  1.000 90.30000  ?  813  ASP AAZA CG  1 
ATOM   1792 O OD1 . ASP A 1 271 ? 57.08400 43.18400 70.13400  1.000 89.60000  ?  813  ASP AAZA OD1 1 
ATOM   1793 O OD2 . ASP A 1 271 ? 56.86800 42.88100 72.32200  1.000 89.84000  ?  813  ASP AAZA OD2 1 
ATOM   1794 N N   . LYS A 1 272 ? 52.83500 40.69600 68.48100  1.000 74.86000  ?  814  LYS AAZA N   1 
ATOM   1795 C CA  . LYS A 1 272 ? 51.97500 39.53700 68.17000  1.000 70.12000  ?  814  LYS AAZA CA  1 
ATOM   1796 C C   . LYS A 1 272 ? 52.78900 38.36100 67.67400  1.000 71.78000  ?  814  LYS AAZA C   1 
ATOM   1797 O O   . LYS A 1 272 ? 52.45300 37.21200 67.96700  1.000 71.37000  ?  814  LYS AAZA O   1 
ATOM   1798 C CB  . LYS A 1 272 ? 50.91600 39.91100 67.16000  1.000 68.47000  ?  814  LYS AAZA CB  1 
ATOM   1799 C CG  . LYS A 1 272 ? 51.47300 40.60400 65.94900  1.000 72.98000  ?  814  LYS AAZA CG  1 
ATOM   1800 C CD  . LYS A 1 272 ? 50.46100 40.85300 64.87300  1.000 66.58000  ?  814  LYS AAZA CD  1 
ATOM   1801 C CE  . LYS A 1 272 ? 51.12400 41.69200 63.83800  1.000 75.48000  ?  814  LYS AAZA CE  1 
ATOM   1802 N NZ  . LYS A 1 272 ? 51.01100 41.08200 62.46000  1.000 91.13000  ?  814  LYS AAZA NZ  1 
ATOM   1803 N N   . GLU A 1 273 ? 53.87400 38.61700 66.95000  1.000 74.02000  ?  815  GLU AAZA N   1 
ATOM   1804 C CA  . GLU A 1 273 ? 54.65300 37.52200 66.39000  1.000 78.15000  ?  815  GLU AAZA CA  1 
ATOM   1805 C C   . GLU A 1 273 ? 55.46900 36.77000 67.43700  1.000 79.02000  ?  815  GLU AAZA C   1 
ATOM   1806 O O   . GLU A 1 273 ? 55.72100 35.57300 67.27500  1.000 77.49000  ?  815  GLU AAZA O   1 
ATOM   1807 C CB  . GLU A 1 273 ? 55.57000 38.05600 65.30200  1.000 81.36000  ?  815  GLU AAZA CB  1 
ATOM   1808 C CG  . GLU A 1 273 ? 54.81600 38.62600 64.15100  1.000 82.70000  ?  815  GLU AAZA CG  1 
ATOM   1809 C CD  . GLU A 1 273 ? 54.10700 37.56200 63.32600  1.000 83.30000  ?  815  GLU AAZA CD  1 
ATOM   1810 O OE1 . GLU A 1 273 ? 54.22200 36.34200 63.62800  1.000 81.43000  ?  815  GLU AAZA OE1 1 
ATOM   1811 O OE2 . GLU A 1 273 ? 53.44600 37.96500 62.34500  1.000 83.56000  ?  815  GLU AAZA OE2 1 
ATOM   1812 N N   . ILE A 1 274 ? 55.91100 37.45300 68.49200  1.000 81.12000  ?  816  ILE AAZA N   1 
ATOM   1813 C CA  . ILE A 1 274 ? 56.61100 36.79100 69.59000  1.000 74.83000  ?  816  ILE AAZA CA  1 
ATOM   1814 C C   . ILE A 1 274 ? 55.62000 35.99900 70.44000  1.000 72.70000  ?  816  ILE AAZA C   1 
ATOM   1815 O O   . ILE A 1 274 ? 55.88900 34.85900 70.83800  1.000 67.68000  ?  816  ILE AAZA O   1 
ATOM   1816 C CB  . ILE A 1 274 ? 57.38000 37.84600 70.41400  1.000 70.64000  ?  816  ILE AAZA CB  1 
ATOM   1817 C CG1 . ILE A 1 274 ? 58.58700 38.37800 69.63500  1.000 85.58000  ?  816  ILE AAZA CG1 1 
ATOM   1818 C CG2 . ILE A 1 274 ? 57.92200 37.27100 71.62500  1.000 68.83000  ?  816  ILE AAZA CG2 1 
ATOM   1819 C CD1 . ILE A 1 274 ? 58.54500 39.87600 69.25400  1.000 87.80000  ?  816  ILE AAZA CD1 1 
ATOM   1820 N N   . ASN A 1 275 ? 54.42900 36.56300 70.66200  1.000 72.40000  ?  817  ASN AAZA N   1 
ATOM   1821 C CA  . ASN A 1 275 ? 53.46700 36.06300 71.63600  1.000 67.86000  ?  817  ASN AAZA CA  1 
ATOM   1822 C C   . ASN A 1 275 ? 52.31500 35.27300 71.04500  1.000 69.73000  ?  817  ASN AAZA C   1 
ATOM   1823 O O   . ASN A 1 275 ? 51.71600 34.46600 71.75600  1.000 70.94000  ?  817  ASN AAZA O   1 
ATOM   1824 C CB  . ASN A 1 275 ? 52.84000 37.21200 72.41100  1.000 66.35000  ?  817  ASN AAZA CB  1 
ATOM   1825 C CG  . ASN A 1 275 ? 53.82000 37.94200 73.23300  1.000 67.67000  ?  817  ASN AAZA CG  1 
ATOM   1826 O OD1 . ASN A 1 275 ? 54.65000 37.34700 73.92400  1.000 65.88000  ?  817  ASN AAZA OD1 1 
ATOM   1827 N ND2 . ASN A 1 275 ? 53.73100 39.26300 73.18500  1.000 73.67000  ?  817  ASN AAZA ND2 1 
ATOM   1828 N N   . SER A 1 276 ? 51.93100 35.50800 69.80800  1.000 71.05000  ?  818  SER AAZA N   1 
ATOM   1829 C CA  . SER A 1 276 ? 50.72900 34.81100 69.36700  1.000 69.51000  ?  818  SER AAZA CA  1 
ATOM   1830 C C   . SER A 1 276 ? 51.03300 34.01400 68.11600  1.000 69.83000  ?  818  SER AAZA C   1 
ATOM   1831 O O   . SER A 1 276 ? 50.32100 34.14200 67.11400  1.000 69.16000  ?  818  SER AAZA O   1 
ATOM   1832 C CB  . SER A 1 276 ? 49.58900 35.79100 69.09500  1.000 68.90000  ?  818  SER AAZA CB  1 
ATOM   1833 O OG  . SER A 1 276 ? 49.13600 36.40400 70.28100  1.000 66.55000  ?  818  SER AAZA OG  1 
ATOM   1834 N N   . PRO A 1 277 ? 52.03500 33.15800 68.14400  1.000 70.41000  ?  819  PRO AAZA N   1 
ATOM   1835 C CA  . PRO A 1 277 ? 52.54000 32.58700 66.89900  1.000 72.56000  ?  819  PRO AAZA CA  1 
ATOM   1836 C C   . PRO A 1 277 ? 51.65900 31.47100 66.34000  1.000 72.34000  ?  819  PRO AAZA C   1 
ATOM   1837 O O   . PRO A 1 277 ? 51.47400 31.37300 65.12200  1.000 69.92000  ?  819  PRO AAZA O   1 
ATOM   1838 C CB  . PRO A 1 277 ? 53.92100 32.08500 67.31300  1.000 69.96000  ?  819  PRO AAZA CB  1 
ATOM   1839 C CG  . PRO A 1 277 ? 53.73800 31.70600 68.69200  1.000 75.21000  ?  819  PRO AAZA CG  1 
ATOM   1840 C CD  . PRO A 1 277 ? 52.69100 32.55600 69.30400  1.000 73.84000  ?  819  PRO AAZA CD  1 
ATOM   1841 N N   . ASN A 1 278 ? 51.09600 30.62400 67.19100  1.000 70.13000  ?  820  ASN AAZA N   1 
ATOM   1842 C CA  . ASN A 1 278 ? 50.29000 29.53900 66.64300  1.000 74.58000  ?  820  ASN AAZA CA  1 
ATOM   1843 C C   . ASN A 1 278 ? 48.89000 29.98300 66.26100  1.000 73.59000  ?  820  ASN AAZA C   1 
ATOM   1844 O O   . ASN A 1 278 ? 48.23700 29.31200 65.45100  1.000 71.37000  ?  820  ASN AAZA O   1 
ATOM   1845 C CB  . ASN A 1 278 ? 50.21500 28.39300 67.63900  1.000 77.04000  ?  820  ASN AAZA CB  1 
ATOM   1846 C CG  . ASN A 1 278 ? 51.56200 28.01300 68.14800  1.000 80.52000  ?  820  ASN AAZA CG  1 
ATOM   1847 O OD1 . ASN A 1 278 ? 52.54500 28.02100 67.39900  1.000 84.68000  ?  820  ASN AAZA OD1 1 
ATOM   1848 N ND2 . ASN A 1 278 ? 51.63800 27.69600 69.42900  1.000 88.25000  ?  820  ASN AAZA ND2 1 
ATOM   1849 N N   . LEU A 1 279 ? 48.40500 31.06800 66.86600  1.000 70.99000  ?  821  LEU AAZA N   1 
ATOM   1850 C CA  . LEU A 1 279 ? 47.14200 31.65000 66.45600  1.000 64.57000  ?  821  LEU AAZA CA  1 
ATOM   1851 C C   . LEU A 1 279 ? 47.29800 32.25800 65.07900  1.000 60.77000  ?  821  LEU AAZA C   1 
ATOM   1852 O O   . LEU A 1 279 ? 46.51400 31.97100 64.17400  1.000 63.15000  ?  821  LEU AAZA O   1 
ATOM   1853 C CB  . LEU A 1 279 ? 46.69400 32.69600 67.48000  1.000 62.55000  ?  821  LEU AAZA CB  1 
ATOM   1854 C CG  . LEU A 1 279 ? 45.53100 33.62500 67.12400  1.000 61.29000  ?  821  LEU AAZA CG  1 
ATOM   1855 C CD1 . LEU A 1 279 ? 44.25700 32.80000 67.01300  1.000 59.67000  ?  821  LEU AAZA CD1 1 
ATOM   1856 C CD2 . LEU A 1 279 ? 45.35900 34.76000 68.11000  1.000 58.88000  ?  821  LEU AAZA CD2 1 
ATOM   1857 N N   . LEU A 1 280 ? 48.34200 33.06300 64.89100  1.000 59.59000  ?  822  LEU AAZA N   1 
ATOM   1858 C CA  . LEU A 1 280 ? 48.60700 33.64300 63.58200  1.000 63.50000  ?  822  LEU AAZA CA  1 
ATOM   1859 C C   . LEU A 1 280 ? 48.79600 32.55800 62.52600  1.000 66.27000  ?  822  LEU AAZA C   1 
ATOM   1860 O O   . LEU A 1 280 ? 48.19400 32.61500 61.44700  1.000 62.29000  ?  822  LEU AAZA O   1 
ATOM   1861 C CB  . LEU A 1 280 ? 49.82800 34.54500 63.66400  1.000 60.31000  ?  822  LEU AAZA CB  1 
ATOM   1862 C CG  . LEU A 1 280 ? 49.62300 35.74900 64.55900  1.000 61.99000  ?  822  LEU AAZA CG  1 
ATOM   1863 C CD1 . LEU A 1 280 ? 50.57800 36.86100 64.19300  1.000 69.19000  ?  822  LEU AAZA CD1 1 
ATOM   1864 C CD2 . LEU A 1 280 ? 48.18600 36.22300 64.47700  1.000 65.08000  ?  822  LEU AAZA CD2 1 
ATOM   1865 N N   . LYS A 1 281 ? 49.61500 31.54500 62.82700  1.000 66.57000  ?  823  LYS AAZA N   1 
ATOM   1866 C CA  . LYS A 1 281 ? 49.75000 30.41900 61.91000  1.000 65.32000  ?  823  LYS AAZA CA  1 
ATOM   1867 C C   . LYS A 1 281 ? 48.39800 29.83200 61.54900  1.000 67.35000  ?  823  LYS AAZA C   1 
ATOM   1868 O O   . LYS A 1 281 ? 48.15300 29.47600 60.39000  1.000 69.63000  ?  823  LYS AAZA O   1 
ATOM   1869 C CB  . LYS A 1 281 ? 50.65100 29.34200 62.50400  1.000 69.25000  ?  823  LYS AAZA CB  1 
ATOM   1870 C CG  . LYS A 1 281 ? 52.09000 29.77700 62.62000  1.000 76.12000  ?  823  LYS AAZA CG  1 
ATOM   1871 C CD  . LYS A 1 281 ? 52.96100 28.67300 63.16000  1.000 82.91000  ?  823  LYS AAZA CD  1 
ATOM   1872 C CE  . LYS A 1 281 ? 54.34600 29.20300 63.50300  1.000 88.80000  ?  823  LYS AAZA CE  1 
ATOM   1873 N NZ  . LYS A 1 281 ? 55.13400 28.10400 64.13000  1.000 100.28000 ?  823  LYS AAZA NZ  1 
ATOM   1874 N N   . MET A 1 282 ? 47.50100 29.74700 62.52100  1.000 66.87000  ?  824  MET AAZA N   1 
ATOM   1875 C CA  . MET A 1 282 ? 46.17400 29.20700 62.26400  1.000 66.10000  ?  824  MET AAZA CA  1 
ATOM   1876 C C   . MET A 1 282 ? 45.33700 30.16800 61.41500  1.000 68.86000  ?  824  MET AAZA C   1 
ATOM   1877 O O   . MET A 1 282 ? 44.64800 29.74400 60.47800  1.000 67.02000  ?  824  MET AAZA O   1 
ATOM   1878 C CB  . MET A 1 282 ? 45.52200 28.90900 63.60600  1.000 65.99000  ?  824  MET AAZA CB  1 
ATOM   1879 C CG  . MET A 1 282 ? 44.29300 28.12000 63.57600  1.000 67.28000  ?  824  MET AAZA CG  1 
ATOM   1880 S SD  . MET A 1 282 ? 42.88200 29.18400 63.42700  1.000 92.26000  ?  824  MET AAZA SD  1 
ATOM   1881 C CE  . MET A 1 282 ? 41.64600 27.87400 63.20900  1.000 85.58000  ?  824  MET AAZA CE  1 
ATOM   1882 N N   . ILE A 1 283 ? 45.40500 31.47100 61.70200  1.000 67.55000  ?  825  ILE AAZA N   1 
ATOM   1883 C CA  . ILE A 1 283 ? 44.66100 32.42600 60.89400  1.000 62.15000  ?  825  ILE AAZA CA  1 
ATOM   1884 C C   . ILE A 1 283 ? 45.24400 32.49600 59.49400  1.000 66.81000  ?  825  ILE AAZA C   1 
ATOM   1885 O O   . ILE A 1 283 ? 44.50900 32.64000 58.51000  1.000 67.71000  ?  825  ILE AAZA O   1 
ATOM   1886 C CB  . ILE A 1 283 ? 44.63600 33.81300 61.55300  1.000 56.35000  ?  825  ILE AAZA CB  1 
ATOM   1887 C CG1 . ILE A 1 283 ? 44.02500 33.70400 62.95000  1.000 58.73000  ?  825  ILE AAZA CG1 1 
ATOM   1888 C CG2 . ILE A 1 283 ? 43.80600 34.76400 60.67800  1.000 55.00000  ?  825  ILE AAZA CG2 1 
ATOM   1889 C CD1 . ILE A 1 283 ? 44.04600 34.97100 63.76900  1.000 52.63000  ?  825  ILE AAZA CD1 1 
ATOM   1890 N N   . ARG A 1 284 ? 46.57000 32.40500 59.36700  1.000 64.20000  ?  826  ARG AAZA N   1 
ATOM   1891 C CA  . ARG A 1 284 ? 47.13700 32.53700 58.03100  1.000 62.24000  ?  826  ARG AAZA CA  1 
ATOM   1892 C C   . ARG A 1 284 ? 46.83800 31.31600 57.19200  1.000 65.06000  ?  826  ARG AAZA C   1 
ATOM   1893 O O   . ARG A 1 284 ? 46.72400 31.41400 55.96600  1.000 62.41000  ?  826  ARG AAZA O   1 
ATOM   1894 C CB  . ARG A 1 284 ? 48.63400 32.75700 58.10400  1.000 62.84000  ?  826  ARG AAZA CB  1 
ATOM   1895 C CG  . ARG A 1 284 ? 48.99100 33.91100 58.93400  1.000 66.01000  ?  826  ARG AAZA CG  1 
ATOM   1896 C CD  . ARG A 1 284 ? 50.15800 34.64400 58.38900  1.000 74.51000  ?  826  ARG AAZA CD  1 
ATOM   1897 N NE  . ARG A 1 284 ? 50.46300 35.77000 59.26500  1.000 82.77000  ?  826  ARG AAZA NE  1 
ATOM   1898 C CZ  . ARG A 1 284 ? 51.34400 35.72700 60.25900  1.000 76.50000  ?  826  ARG AAZA CZ  1 
ATOM   1899 N NH1 . ARG A 1 284 ? 52.06200 34.63000 60.51000  1.000 66.54000  ?  826  ARG AAZA NH1 1 
ATOM   1900 N NH2 . ARG A 1 284 ? 51.50600 36.80700 61.01900  1.000 74.91000  ?  826  ARG AAZA NH2 1 
ATOM   1901 N N   . HIS A 1 285 ? 46.70000 30.15800 57.83400  1.000 68.09000  ?  827  HIS AAZA N   1 
ATOM   1902 C CA  . HIS A 1 285 ? 46.27200 28.98300 57.09400  1.000 67.24000  ?  827  HIS AAZA CA  1 
ATOM   1903 C C   . HIS A 1 285 ? 44.89500 29.19000 56.49200  1.000 68.05000  ?  827  HIS AAZA C   1 
ATOM   1904 O O   . HIS A 1 285 ? 44.68800 28.96700 55.29400  1.000 68.59000  ?  827  HIS AAZA O   1 
ATOM   1905 C CB  . HIS A 1 285 ? 46.22700 27.74800 57.96500  1.000 64.11000  ?  827  HIS AAZA CB  1 
ATOM   1906 C CG  . HIS A 1 285 ? 45.65600 26.58600 57.23400  1.000 69.66000  ?  827  HIS AAZA CG  1 
ATOM   1907 N ND1 . HIS A 1 285 ? 44.35200 26.17600 57.39600  1.000 75.67000  ?  827  HIS AAZA ND1 1 
ATOM   1908 C CD2 . HIS A 1 285 ? 46.19200 25.78400 56.28500  1.000 72.21000  ?  827  HIS AAZA CD2 1 
ATOM   1909 C CE1 . HIS A 1 285 ? 44.10900 25.16000 56.58800  1.000 76.08000  ?  827  HIS AAZA CE1 1 
ATOM   1910 N NE2 . HIS A 1 285 ? 45.20900 24.90400 55.90300  1.000 79.96000  ?  827  HIS AAZA NE2 1 
ATOM   1911 N N   . THR A 1 286 ? 43.92200 29.58500 57.31000  1.000 65.32000  ?  828  THR AAZA N   1 
ATOM   1912 C CA  . THR A 1 286 ? 42.60700 29.68100 56.70800  1.000 69.55000  ?  828  THR AAZA CA  1 
ATOM   1913 C C   . THR A 1 286 ? 42.54900 30.84200 55.72200  1.000 67.56000  ?  828  THR AAZA C   1 
ATOM   1914 O O   . THR A 1 286 ? 41.74600 30.79500 54.78600  1.000 70.94000  ?  828  THR AAZA O   1 
ATOM   1915 C CB  . THR A 1 286 ? 41.50900 29.79000 57.76300  1.000 66.34000  ?  828  THR AAZA CB  1 
ATOM   1916 O OG1 . THR A 1 286 ? 41.35200 31.14300 58.15800  1.000 64.19000  ?  828  THR AAZA OG1 1 
ATOM   1917 C CG2 . THR A 1 286 ? 41.95400 29.04700 58.96900  1.000 72.27000  ?  828  THR AAZA CG2 1 
ATOM   1918 N N   . THR A 1 287 ? 43.41300 31.85400 55.85800  1.000 61.60000  ?  829  THR AAZA N   1 
ATOM   1919 C CA  . THR A 1 287 ? 43.40400 32.88600 54.83400  1.000 62.03000  ?  829  THR AAZA CA  1 
ATOM   1920 C C   . THR A 1 287 ? 43.88800 32.32900 53.51700  1.000 64.96000  ?  829  THR AAZA C   1 
ATOM   1921 O O   . THR A 1 287 ? 43.36700 32.69200 52.45900  1.000 67.45000  ?  829  THR AAZA O   1 
ATOM   1922 C CB  . THR A 1 287 ? 44.23300 34.09500 55.23200  1.000 61.81000  ?  829  THR AAZA CB  1 
ATOM   1923 O OG1 . THR A 1 287 ? 43.51100 34.84600 56.19700  1.000 65.85000  ?  829  THR AAZA OG1 1 
ATOM   1924 C CG2 . THR A 1 287 ? 44.41100 35.00400 54.05400  1.000 58.18000  ?  829  THR AAZA CG2 1 
ATOM   1925 N N   . ASN A 1 288 ? 44.83900 31.40100 53.55500  1.000 67.96000  ?  830  ASN AAZA N   1 
ATOM   1926 C CA  . ASN A 1 288 ? 45.39100 30.90600 52.29800  1.000 69.28000  ?  830  ASN AAZA CA  1 
ATOM   1927 C C   . ASN A 1 288 ? 44.41600 30.00000 51.55400  1.000 72.60000  ?  830  ASN AAZA C   1 
ATOM   1928 O O   . ASN A 1 288 ? 44.25800 30.13500 50.32900  1.000 71.25000  ?  830  ASN AAZA O   1 
ATOM   1929 C CB  . ASN A 1 288 ? 46.71200 30.21300 52.54600  1.000 65.57000  ?  830  ASN AAZA CB  1 
ATOM   1930 C CG  . ASN A 1 288 ? 47.85300 31.16900 52.39600  1.000 77.66000  ?  830  ASN AAZA CG  1 
ATOM   1931 O OD1 . ASN A 1 288 ? 48.67800 31.01300 51.49400  1.000 85.29000  ?  830  ASN AAZA OD1 1 
ATOM   1932 N ND2 . ASN A 1 288 ? 47.87200 32.22600 53.23200  1.000 71.60000  ?  830  ASN AAZA ND2 1 
ATOM   1933 N N   . LEU A 1 289 ? 43.73000 29.09200 52.25500  1.000 68.66000  ?  831  LEU AAZA N   1 
ATOM   1934 C CA  . LEU A 1 289 ? 42.76200 28.26700 51.54100  1.000 69.84000  ?  831  LEU AAZA CA  1 
ATOM   1935 C C   . LEU A 1 289 ? 41.65100 29.10700 50.93400  1.000 73.15000  ?  831  LEU AAZA C   1 
ATOM   1936 O O   . LEU A 1 289 ? 41.25200 28.88100 49.78500  1.000 75.23000  ?  831  LEU AAZA O   1 
ATOM   1937 C CB  . LEU A 1 289 ? 42.17400 27.20500 52.43200  1.000 67.68000  ?  831  LEU AAZA CB  1 
ATOM   1938 C CG  . LEU A 1 289 ? 42.91100 25.92800 52.13200  1.000 72.55000  ?  831  LEU AAZA CG  1 
ATOM   1939 C CD1 . LEU A 1 289 ? 44.39600 26.02700 52.49200  1.000 71.58000  ?  831  LEU AAZA CD1 1 
ATOM   1940 C CD2 . LEU A 1 289 ? 42.22300 24.92800 52.94300  1.000 81.72000  ?  831  LEU AAZA CD2 1 
ATOM   1941 N N   . THR A 1 290 ? 41.13900 30.08900 51.68200  1.000 69.01000  ?  832  THR AAZA N   1 
ATOM   1942 C CA  . THR A 1 290 ? 40.12700 30.96700 51.10800  1.000 66.67000  ?  832  THR AAZA CA  1 
ATOM   1943 C C   . THR A 1 290 ? 40.62400 31.59300 49.80800  1.000 68.67000  ?  832  THR AAZA C   1 
ATOM   1944 O O   . THR A 1 290 ? 39.89800 31.63700 48.81100  1.000 64.79000  ?  832  THR AAZA O   1 
ATOM   1945 C CB  . THR A 1 290 ? 39.73400 32.02000 52.13100  1.000 60.48000  ?  832  THR AAZA CB  1 
ATOM   1946 O OG1 . THR A 1 290 ? 39.31600 31.34200 53.31200  1.000 72.54000  ?  832  THR AAZA OG1 1 
ATOM   1947 C CG2 . THR A 1 290 ? 38.59100 32.83100 51.65300  1.000 60.78000  ?  832  THR AAZA CG2 1 
ATOM   1948 N N   . LEU A 1 291 ? 41.88300 32.02500 49.78300  1.000 69.34000  ?  833  LEU AAZA N   1 
ATOM   1949 C CA  . LEU A 1 291 ? 42.42700 32.62200 48.57400  1.000 65.00000  ?  833  LEU AAZA CA  1 
ATOM   1950 C C   . LEU A 1 291 ? 42.66200 31.57900 47.50400  1.000 67.78000  ?  833  LEU AAZA C   1 
ATOM   1951 O O   . LEU A 1 291 ? 42.50800 31.86300 46.30800  1.000 67.74000  ?  833  LEU AAZA O   1 
ATOM   1952 C CB  . LEU A 1 291 ? 43.73200 33.34300 48.88400  1.000 61.71000  ?  833  LEU AAZA CB  1 
ATOM   1953 C CG  . LEU A 1 291 ? 43.49900 34.64500 49.61400  1.000 56.95000  ?  833  LEU AAZA CG  1 
ATOM   1954 C CD1 . LEU A 1 291 ? 44.72200 35.46000 49.45800  1.000 58.11000  ?  833  LEU AAZA CD1 1 
ATOM   1955 C CD2 . LEU A 1 291 ? 42.28200 35.35100 49.05800  1.000 53.77000  ?  833  LEU AAZA CD2 1 
ATOM   1956 N N   . TRP A 1 292 ? 43.05900 30.37600 47.91000  1.000 68.37000  ?  834  TRP AAZA N   1 
ATOM   1957 C CA  . TRP A 1 292 ? 43.26000 29.31900 46.93200  1.000 69.55000  ?  834  TRP AAZA CA  1 
ATOM   1958 C C   . TRP A 1 292 ? 41.94400 28.97400 46.24300  1.000 69.65000  ?  834  TRP AAZA C   1 
ATOM   1959 O O   . TRP A 1 292 ? 41.84000 29.03700 45.01100  1.000 69.23000  ?  834  TRP AAZA O   1 
ATOM   1960 C CB  . TRP A 1 292 ? 43.86400 28.12300 47.63300  1.000 66.18000  ?  834  TRP AAZA CB  1 
ATOM   1961 C CG  . TRP A 1 292 ? 44.15900 26.98200 46.76800  1.000 69.18000  ?  834  TRP AAZA CG  1 
ATOM   1962 C CD1 . TRP A 1 292 ? 45.15100 26.88500 45.83600  1.000 66.75000  ?  834  TRP AAZA CD1 1 
ATOM   1963 C CD2 . TRP A 1 292 ? 43.49700 25.72300 46.78600  1.000 72.86000  ?  834  TRP AAZA CD2 1 
ATOM   1964 N NE1 . TRP A 1 292 ? 45.14400 25.63800 45.27600  1.000 64.70000  ?  834  TRP AAZA NE1 1 
ATOM   1965 C CE2 . TRP A 1 292 ? 44.13300 24.90700 45.84000  1.000 68.05000  ?  834  TRP AAZA CE2 1 
ATOM   1966 C CE3 . TRP A 1 292 ? 42.42200 25.20500 47.51600  1.000 74.17000  ?  834  TRP AAZA CE3 1 
ATOM   1967 C CZ2 . TRP A 1 292 ? 43.72400 23.61600 45.59700  1.000 73.57000  ?  834  TRP AAZA CZ2 1 
ATOM   1968 C CZ3 . TRP A 1 292 ? 42.03100 23.91900 47.28100  1.000 68.64000  ?  834  TRP AAZA CZ3 1 
ATOM   1969 C CH2 . TRP A 1 292 ? 42.67900 23.13600 46.33700  1.000 71.15000  ?  834  TRP AAZA CH2 1 
ATOM   1970 N N   . PHE A 1 293 ? 40.91600 28.65100 47.03400  1.000 66.85000  ?  835  PHE AAZA N   1 
ATOM   1971 C CA  . PHE A 1 293 ? 39.55900 28.51400 46.51300  1.000 64.65000  ?  835  PHE AAZA CA  1 
ATOM   1972 C C   . PHE A 1 293 ? 39.21100 29.61700 45.52600  1.000 63.85000  ?  835  PHE AAZA C   1 
ATOM   1973 O O   . PHE A 1 293 ? 38.64500 29.35500 44.46500  1.000 68.82000  ?  835  PHE AAZA O   1 
ATOM   1974 C CB  . PHE A 1 293 ? 38.56500 28.50700 47.66400  1.000 62.74000  ?  835  PHE AAZA CB  1 
ATOM   1975 C CG  . PHE A 1 293 ? 38.57800 27.23800 48.44600  1.000 69.45000  ?  835  PHE AAZA CG  1 
ATOM   1976 C CD1 . PHE A 1 293 ? 38.73600 26.02500 47.80300  1.000 67.05000  ?  835  PHE AAZA CD1 1 
ATOM   1977 C CD2 . PHE A 1 293 ? 38.48100 27.25200 49.83000  1.000 67.10000  ?  835  PHE AAZA CD2 1 
ATOM   1978 C CE1 . PHE A 1 293 ? 38.74600 24.86000 48.52400  1.000 65.83000  ?  835  PHE AAZA CE1 1 
ATOM   1979 C CE2 . PHE A 1 293 ? 38.50900 26.08500 50.54700  1.000 64.90000  ?  835  PHE AAZA CE2 1 
ATOM   1980 C CZ  . PHE A 1 293 ? 38.62800 24.89300 49.90100  1.000 63.87000  ?  835  PHE AAZA CZ  1 
ATOM   1981 N N   . GLU A 1 294 ? 39.52400 30.86100 45.85900  1.000 63.74000  ?  836  GLU AAZA N   1 
ATOM   1982 C CA  . GLU A 1 294 ? 39.20700 31.95400 44.94900  1.000 61.71000  ?  836  GLU AAZA CA  1 
ATOM   1983 C C   . GLU A 1 294 ? 40.03600 31.87100 43.67300  1.000 68.55000  ?  836  GLU AAZA C   1 
ATOM   1984 O O   . GLU A 1 294 ? 39.51000 32.06400 42.56400  1.000 68.30000  ?  836  GLU AAZA O   1 
ATOM   1985 C CB  . GLU A 1 294 ? 39.43600 33.28500 45.64200  1.000 57.00000  ?  836  GLU AAZA CB  1 
ATOM   1986 C CG  . GLU A 1 294 ? 38.39800 33.70300 46.60400  1.000 58.60000  ?  836  GLU AAZA CG  1 
ATOM   1987 C CD  . GLU A 1 294 ? 38.73800 35.07500 47.16900  1.000 72.08000  ?  836  GLU AAZA CD  1 
ATOM   1988 O OE1 . GLU A 1 294 ? 39.34100 35.89800 46.41200  1.000 65.51000  ?  836  GLU AAZA OE1 1 
ATOM   1989 O OE2 . GLU A 1 294 ? 38.39800 35.34400 48.35900  1.000 71.19000  ?  836  GLU AAZA OE2 1 
ATOM   1990 N N   . LYS A 1 295 ? 41.34100 31.60800 43.81200  1.000 66.94000  ?  837  LYS AAZA N   1 
ATOM   1991 C CA  . LYS A 1 295 ? 42.20600 31.53000 42.64100  1.000 66.41000  ?  837  LYS AAZA CA  1 
ATOM   1992 C C   . LYS A 1 295 ? 41.79300 30.35700 41.74800  1.000 70.90000  ?  837  LYS AAZA C   1 
ATOM   1993 O O   . LYS A 1 295 ? 41.82400 30.46200 40.51600  1.000 69.05000  ?  837  LYS AAZA O   1 
ATOM   1994 C CB  . LYS A 1 295 ? 43.66500 31.43000 43.09700  1.000 66.57000  ?  837  LYS AAZA CB  1 
ATOM   1995 C CG  . LYS A 1 295 ? 44.68500 31.10900 42.02100  1.000 70.98000  ?  837  LYS AAZA CG  1 
ATOM   1996 C CD  . LYS A 1 295 ? 46.03900 31.75200 42.33400  1.000 70.68000  ?  837  LYS AAZA CD  1 
ATOM   1997 C CE  . LYS A 1 295 ? 47.23000 30.94800 41.79300  1.000 71.59000  ?  837  LYS AAZA CE  1 
ATOM   1998 N NZ  . LYS A 1 295 ? 47.55500 29.70100 42.56300  1.000 79.96000  ?  837  LYS AAZA NZ  1 
ATOM   1999 N N   . CYS A 1 296 ? 41.31800 29.28100 42.36500  1.000 68.67000  ?  838  CYS AAZA N   1 
ATOM   2000 C CA  . CYS A 1 296 ? 40.86600 28.10800 41.57700  1.000 68.77000  ?  838  CYS AAZA CA  1 
ATOM   2001 C C   . CYS A 1 296 ? 39.60100 28.47000 40.79100  1.000 67.41000  ?  838  CYS AAZA C   1 
ATOM   2002 O O   . CYS A 1 296 ? 39.45400 27.96700 39.67300  1.000 69.86000  ?  838  CYS AAZA O   1 
ATOM   2003 C CB  . CYS A 1 296 ? 40.62700 26.92000 42.49600  1.000 66.20000  ?  838  CYS AAZA CB  1 
ATOM   2004 S SG  . CYS A 1 296 ? 42.10500 26.42900 43.41700  1.000 79.42000  ?  838  CYS AAZA SG  1 
ATOM   2005 N N   . ILE A 1 297 ? 38.72700 29.31100 41.34600  1.000 66.02000  ?  839  ILE AAZA N   1 
ATOM   2006 C CA  . ILE A 1 297 ? 37.49600 29.62400 40.64300  1.000 65.26000  ?  839  ILE AAZA CA  1 
ATOM   2007 C C   . ILE A 1 297 ? 37.77300 30.55500 39.47600  1.000 64.84000  ?  839  ILE AAZA C   1 
ATOM   2008 O O   . ILE A 1 297 ? 37.49400 30.20200 38.33000  1.000 64.89000  ?  839  ILE AAZA O   1 
ATOM   2009 C CB  . ILE A 1 297 ? 36.44700 30.20100 41.60200  1.000 64.16000  ?  839  ILE AAZA CB  1 
ATOM   2010 C CG1 . ILE A 1 297 ? 35.82800 29.06200 42.41600  1.000 62.63000  ?  839  ILE AAZA CG1 1 
ATOM   2011 C CG2 . ILE A 1 297 ? 35.36800 30.91800 40.81900  1.000 54.31000  ?  839  ILE AAZA CG2 1 
ATOM   2012 C CD1 . ILE A 1 297 ? 34.95000 29.54200 43.56800  1.000 59.76000  ?  839  ILE AAZA CD1 1 
ATOM   2013 N N   . VAL A 1 298 ? 38.35900 31.73100 39.73600  1.000 63.95000  ?  840  VAL AAZA N   1 
ATOM   2014 C CA  . VAL A 1 298 ? 38.43500 32.75600 38.68800  1.000 64.20000  ?  840  VAL AAZA CA  1 
ATOM   2015 C C   . VAL A 1 298 ? 39.55700 32.51100 37.68500  1.000 67.93000  ?  840  VAL AAZA C   1 
ATOM   2016 O O   . VAL A 1 298 ? 39.55100 33.10600 36.59700  1.000 64.65000  ?  840  VAL AAZA O   1 
ATOM   2017 C CB  . VAL A 1 298 ? 38.59000 34.16900 39.27000  1.000 62.24000  ?  840  VAL AAZA CB  1 
ATOM   2018 C CG1 . VAL A 1 298 ? 37.48600 34.43800 40.22800  1.000 66.11000  ?  840  VAL AAZA CG1 1 
ATOM   2019 C CG2 . VAL A 1 298 ? 39.92600 34.34300 39.93300  1.000 60.91000  ?  840  VAL AAZA CG2 1 
ATOM   2020 N N   . GLU A 1 299 ? 40.52400 31.66500 38.01500  1.000 73.12000  ?  841  GLU AAZA N   1 
ATOM   2021 C CA  . GLU A 1 299 ? 41.55200 31.28400 37.06000  1.000 73.38000  ?  841  GLU AAZA CA  1 
ATOM   2022 C C   . GLU A 1 299 ? 41.11900 30.11100 36.19500  1.000 71.20000  ?  841  GLU AAZA C   1 
ATOM   2023 O O   . GLU A 1 299 ? 41.85000 29.73100 35.28500  1.000 77.48000  ?  841  GLU AAZA O   1 
ATOM   2024 C CB  . GLU A 1 299 ? 42.86400 30.95700 37.78900  1.000 73.22000  ?  841  GLU AAZA CB  1 
ATOM   2025 C CG  . GLU A 1 299 ? 43.82500 32.14000 37.96800  1.000 68.31000  ?  841  GLU AAZA CG  1 
ATOM   2026 C CD  . GLU A 1 299 ? 45.21500 31.67100 38.36200  1.000 76.29000  ?  841  GLU AAZA CD  1 
ATOM   2027 O OE1 . GLU A 1 299 ? 45.35600 30.45800 38.65600  1.000 79.18000  ?  841  GLU AAZA OE1 1 
ATOM   2028 O OE2 . GLU A 1 299 ? 46.17300 32.48600 38.34300  1.000 74.12000  ?  841  GLU AAZA OE2 1 
ATOM   2029 N N   . THR A 1 300 ? 39.96700 29.51300 36.47200  1.000 69.65000  ?  842  THR AAZA N   1 
ATOM   2030 C CA  . THR A 1 300 ? 39.30200 28.61500 35.52900  1.000 69.99000  ?  842  THR AAZA CA  1 
ATOM   2031 C C   . THR A 1 300 ? 38.46500 29.51000 34.61100  1.000 71.94000  ?  842  THR AAZA C   1 
ATOM   2032 O O   . THR A 1 300 ? 37.30400 29.84100 34.89100  1.000 69.58000  ?  842  THR AAZA O   1 
ATOM   2033 C CB  . THR A 1 300 ? 38.46700 27.56300 36.25900  1.000 70.67000  ?  842  THR AAZA CB  1 
ATOM   2034 O OG1 . THR A 1 300 ? 39.31800 26.68200 36.99000  1.000 73.42000  ?  842  THR AAZA OG1 1 
ATOM   2035 C CG2 . THR A 1 300 ? 37.75100 26.73200 35.30000  1.000 73.88000  ?  842  THR AAZA CG2 1 
ATOM   2036 N N   . GLU A 1 301 ? 39.07500 29.92300 33.49600  1.000 70.70000  ?  843  GLU AAZA N   1 
ATOM   2037 C CA  . GLU A 1 301 ? 38.44000 30.89000 32.60300  1.000 73.14000  ?  843  GLU AAZA CA  1 
ATOM   2038 C C   . GLU A 1 301 ? 37.22600 30.30800 31.85400  1.000 78.32000  ?  843  GLU AAZA C   1 
ATOM   2039 O O   . GLU A 1 301 ? 36.27300 31.04300 31.57100  1.000 75.79000  ?  843  GLU AAZA O   1 
ATOM   2040 C CB  . GLU A 1 301 ? 39.49300 31.41700 31.63500  1.000 68.64000  ?  843  GLU AAZA CB  1 
ATOM   2041 C CG  . GLU A 1 301 ? 40.66200 32.18700 32.28700  1.000 76.44000  ?  843  GLU AAZA CG  1 
ATOM   2042 C CD  . GLU A 1 301 ? 41.95700 31.34900 32.44600  1.000 83.92000  ?  843  GLU AAZA CD  1 
ATOM   2043 O OE1 . GLU A 1 301 ? 41.91900 30.11200 32.22200  1.000 84.67000  ?  843  GLU AAZA OE1 1 
ATOM   2044 O OE2 . GLU A 1 301 ? 43.03000 31.94000 32.74500  1.000 81.94000  ?  843  GLU AAZA OE2 1 
ATOM   2045 N N   . ASN A 1 302 ? 37.22700 29.00100 31.54800  1.000 76.55000  ?  844  ASN AAZA N   1 
ATOM   2046 C CA  . ASN A 1 302 ? 36.15000 28.35100 30.80100  1.000 72.96000  ?  844  ASN AAZA CA  1 
ATOM   2047 C C   . ASN A 1 302 ? 34.89700 28.19500 31.65900  1.000 74.53000  ?  844  ASN AAZA C   1 
ATOM   2048 O O   . ASN A 1 302 ? 34.98300 27.73600 32.79700  1.000 76.93000  ?  844  ASN AAZA O   1 
ATOM   2049 C CB  . ASN A 1 302 ? 36.62700 26.97400 30.32300  1.000 78.56000  ?  844  ASN AAZA CB  1 
ATOM   2050 C CG  . ASN A 1 302 ? 35.47400 26.04100 29.90700  1.000 82.77000  ?  844  ASN AAZA CG  1 
ATOM   2051 O OD1 . ASN A 1 302 ? 34.86500 25.36000 30.75300  1.000 78.41000  ?  844  ASN AAZA OD1 1 
ATOM   2052 N ND2 . ASN A 1 302 ? 35.21000 25.97000 28.59400  1.000 75.66000  ?  844  ASN AAZA ND2 1 
ATOM   2053 N N   . LEU A 1 303 ? 33.72200 28.52900 31.10000  1.000 69.84000  ?  845  LEU AAZA N   1 
ATOM   2054 C CA  . LEU A 1 303 ? 32.51300 28.54200 31.92500  1.000 68.23000  ?  845  LEU AAZA CA  1 
ATOM   2055 C C   . LEU A 1 303 ? 32.14700 27.15700 32.41300  1.000 74.07000  ?  845  LEU AAZA C   1 
ATOM   2056 O O   . LEU A 1 303 ? 31.65700 27.00000 33.53600  1.000 75.92000  ?  845  LEU AAZA O   1 
ATOM   2057 C CB  . LEU A 1 303 ? 31.31900 29.12800 31.18700  1.000 69.74000  ?  845  LEU AAZA CB  1 
ATOM   2058 C CG  . LEU A 1 303 ? 30.04000 29.13000 32.04900  1.000 65.54000  ?  845  LEU AAZA CG  1 
ATOM   2059 C CD1 . LEU A 1 303 ? 30.28200 29.84500 33.33600  1.000 75.42000  ?  845  LEU AAZA CD1 1 
ATOM   2060 C CD2 . LEU A 1 303 ? 28.83900 29.76400 31.38200  1.000 76.95000  ?  845  LEU AAZA CD2 1 
ATOM   2061 N N   . GLU A 1 304 ? 32.35000 26.13700 31.59000  1.000 78.84000  ?  846  GLU AAZA N   1 
ATOM   2062 C CA  . GLU A 1 304 ? 31.96100 24.80900 32.05000  1.000 82.58000  ?  846  GLU AAZA CA  1 
ATOM   2063 C C   . GLU A 1 304 ? 32.93000 24.26000 33.09400  1.000 76.83000  ?  846  GLU AAZA C   1 
ATOM   2064 O O   . GLU A 1 304 ? 32.48800 23.67400 34.08900  1.000 75.05000  ?  846  GLU AAZA O   1 
ATOM   2065 C CB  . GLU A 1 304 ? 31.82800 23.85000 30.87300  1.000 88.11000  ?  846  GLU AAZA CB  1 
ATOM   2066 C CG  . GLU A 1 304 ? 31.04100 22.60200 31.21300  1.000 96.09000  ?  846  GLU AAZA CG  1 
ATOM   2067 C CD  . GLU A 1 304 ? 30.90700 21.66800 30.03300  1.000 108.68000 ?  846  GLU AAZA CD  1 
ATOM   2068 O OE1 . GLU A 1 304 ? 30.61000 22.14400 28.90900  1.000 119.39000 ?  846  GLU AAZA OE1 1 
ATOM   2069 O OE2 . GLU A 1 304 ? 31.15300 20.45700 30.22400  1.000 112.92000 ?  846  GLU AAZA OE2 1 
ATOM   2070 N N   . GLU A 1 305 ? 34.24600 24.43700 32.89400  1.000 72.39000  ?  847  GLU AAZA N   1 
ATOM   2071 C CA  . GLU A 1 305 ? 35.20200 23.96800 33.89500  1.000 75.76000  ?  847  GLU AAZA CA  1 
ATOM   2072 C C   . GLU A 1 305 ? 35.03400 24.69800 35.22600  1.000 76.87000  ?  847  GLU AAZA C   1 
ATOM   2073 O O   . GLU A 1 305 ? 35.25700 24.11500 36.29600  1.000 73.96000  ?  847  GLU AAZA O   1 
ATOM   2074 C CB  . GLU A 1 305 ? 36.63200 24.13700 33.38700  1.000 76.25000  ?  847  GLU AAZA CB  1 
ATOM   2075 C CG  . GLU A 1 305 ? 36.95100 23.45900 32.07500  1.000 82.76000  ?  847  GLU AAZA CG  1 
ATOM   2076 C CD  . GLU A 1 305 ? 38.43200 23.59500 31.67600  1.000 91.49000  ?  847  GLU AAZA CD  1 
ATOM   2077 O OE1 . GLU A 1 305 ? 38.98100 24.73500 31.68100  1.000 91.36000  ?  847  GLU AAZA OE1 1 
ATOM   2078 O OE2 . GLU A 1 305 ? 39.05100 22.54600 31.36700  1.000 91.24000  ?  847  GLU AAZA OE2 1 
ATOM   2079 N N   . ARG A 1 306 ? 34.65100 25.97300 35.17700  1.000 76.51000  ?  848  ARG AAZA N   1 
ATOM   2080 C CA  . ARG A 1 306 ? 34.45900 26.75000 36.39300  1.000 72.99000  ?  848  ARG AAZA CA  1 
ATOM   2081 C C   . ARG A 1 306 ? 33.27400 26.21300 37.19400  1.000 76.19000  ?  848  ARG AAZA C   1 
ATOM   2082 O O   . ARG A 1 306 ? 33.36400 26.02800 38.41600  1.000 73.75000  ?  848  ARG AAZA O   1 
ATOM   2083 C CB  . ARG A 1 306 ? 34.26600 28.22400 36.02400  1.000 67.58000  ?  848  ARG AAZA CB  1 
ATOM   2084 C CG  . ARG A 1 306 ? 34.04800 29.13900 37.18500  1.000 66.98000  ?  848  ARG AAZA CG  1 
ATOM   2085 C CD  . ARG A 1 306 ? 34.44900 30.54600 36.85300  1.000 65.57000  ?  848  ARG AAZA CD  1 
ATOM   2086 N NE  . ARG A 1 306 ? 33.55400 31.14800 35.87300  1.000 72.82000  ?  848  ARG AAZA NE  1 
ATOM   2087 C CZ  . ARG A 1 306 ? 33.89500 31.39400 34.61200  1.000 81.61000  ?  848  ARG AAZA CZ  1 
ATOM   2088 N NH1 . ARG A 1 306 ? 35.10600 31.08900 34.15400  1.000 79.43000  ?  848  ARG AAZA NH1 1 
ATOM   2089 N NH2 . ARG A 1 306 ? 33.00200 31.95600 33.78800  1.000 70.46000  ?  848  ARG AAZA NH2 1 
ATOM   2090 N N   . VAL A 1 307 ? 32.15600 25.91900 36.52100  1.000 77.00000  ?  849  VAL AAZA N   1 
ATOM   2091 C CA  . VAL A 1 307 ? 31.01500 25.38800 37.25700  1.000 73.69000  ?  849  VAL AAZA CA  1 
ATOM   2092 C C   . VAL A 1 307 ? 31.39700 24.05400 37.88500  1.000 74.74000  ?  849  VAL AAZA C   1 
ATOM   2093 O O   . VAL A 1 307 ? 30.88700 23.69000 38.95200  1.000 76.32000  ?  849  VAL AAZA O   1 
ATOM   2094 C CB  . VAL A 1 307 ? 29.78200 25.24900 36.34900  1.000 70.59000  ?  849  VAL AAZA CB  1 
ATOM   2095 C CG1 . VAL A 1 307 ? 28.60800 24.80700 37.17100  1.000 75.07000  ?  849  VAL AAZA CG1 1 
ATOM   2096 C CG2 . VAL A 1 307 ? 29.47400 26.53400 35.64100  1.000 72.31000  ?  849  VAL AAZA CG2 1 
ATOM   2097 N N   . ALA A 1 308 ? 32.33500 23.32900 37.25800  1.000 72.14000  ?  850  ALA AAZA N   1 
ATOM   2098 C CA  . ALA A 1 308 ? 32.87200 22.10400 37.84000  1.000 72.11000  ?  850  ALA AAZA CA  1 
ATOM   2099 C C   . ALA A 1 308 ? 33.72000 22.38500 39.08300  1.000 76.98000  ?  850  ALA AAZA C   1 
ATOM   2100 O O   . ALA A 1 308 ? 33.70100 21.60100 40.04400  1.000 75.51000  ?  850  ALA AAZA O   1 
ATOM   2101 C CB  . ALA A 1 308 ? 33.69000 21.36000 36.79500  1.000 72.37000  ?  850  ALA AAZA CB  1 
ATOM   2102 N N   . VAL A 1 309 ? 34.48000 23.48400 39.08500  1.000 76.56000  ?  851  VAL AAZA N   1 
ATOM   2103 C CA  . VAL A 1 309 ? 35.31100 23.79800 40.24500  1.000 76.18000  ?  851  VAL AAZA CA  1 
ATOM   2104 C C   . VAL A 1 309 ? 34.45000 24.30400 41.39100  1.000 74.78000  ?  851  VAL AAZA C   1 
ATOM   2105 O O   . VAL A 1 309 ? 34.59400 23.85500 42.53400  1.000 78.18000  ?  851  VAL AAZA O   1 
ATOM   2106 C CB  . VAL A 1 309 ? 36.40500 24.81700 39.88700  1.000 78.57000  ?  851  VAL AAZA CB  1 
ATOM   2107 C CG1 . VAL A 1 309 ? 36.95700 25.48900 41.16900  1.000 70.05000  ?  851  VAL AAZA CG1 1 
ATOM   2108 C CG2 . VAL A 1 309 ? 37.51900 24.14900 39.05500  1.000 77.40000  ?  851  VAL AAZA CG2 1 
ATOM   2109 N N   . VAL A 1 310 ? 33.54300 25.24300 41.10600  1.000 70.93000  ?  852  VAL AAZA N   1 
ATOM   2110 C CA  . VAL A 1 310 ? 32.62300 25.72400 42.14100  1.000 72.73000  ?  852  VAL AAZA CA  1 
ATOM   2111 C C   . VAL A 1 310 ? 31.84400 24.56100 42.72700  1.000 75.13000  ?  852  VAL AAZA C   1 
ATOM   2112 O O   . VAL A 1 310 ? 31.65900 24.45500 43.94600  1.000 71.53000  ?  852  VAL AAZA O   1 
ATOM   2113 C CB  . VAL A 1 310 ? 31.66500 26.78700 41.57700  1.000 71.43000  ?  852  VAL AAZA CB  1 
ATOM   2114 C CG1 . VAL A 1 310 ? 30.60500 27.12100 42.60200  1.000 65.56000  ?  852  VAL AAZA CG1 1 
ATOM   2115 C CG2 . VAL A 1 310 ? 32.41800 28.03600 41.14900  1.000 70.22000  ?  852  VAL AAZA CG2 1 
ATOM   2116 N N   . SER A 1 311 ? 31.36500 23.67800 41.85500  1.000 78.71000  ?  853  SER AAZA N   1 
ATOM   2117 C CA  . SER A 1 311 ? 30.64500 22.50000 42.30600  1.000 78.22000  ?  853  SER AAZA CA  1 
ATOM   2118 C C   . SER A 1 311 ? 31.50700 21.66900 43.25700  1.000 81.98000  ?  853  SER AAZA C   1 
ATOM   2119 O O   . SER A 1 311 ? 31.05100 21.26500 44.33600  1.000 80.98000  ?  853  SER AAZA O   1 
ATOM   2120 C CB  . SER A 1 311 ? 30.20200 21.69000 41.08900  1.000 76.29000  ?  853  SER AAZA CB  1 
ATOM   2121 O OG  . SER A 1 311 ? 29.20500 20.75200 41.43000  1.000 93.07000  ?  853  SER AAZA OG  1 
ATOM   2122 N N   . ARG A 1 312 ? 32.77100 21.41800 42.88400  1.000 80.17000  ?  854  ARG AAZA N   1 
ATOM   2123 C CA  . ARG A 1 312 ? 33.60100 20.56100 43.72100  1.000 78.33000  ?  854  ARG AAZA CA  1 
ATOM   2124 C C   . ARG A 1 312 ? 33.89600 21.22300 45.05500  1.000 78.51000  ?  854  ARG AAZA C   1 
ATOM   2125 O O   . ARG A 1 312 ? 34.04100 20.52800 46.07000  1.000 79.88000  ?  854  ARG AAZA O   1 
ATOM   2126 C CB  . ARG A 1 312 ? 34.90300 20.19600 43.01100  1.000 77.05000  ?  854  ARG AAZA CB  1 
ATOM   2127 C CG  . ARG A 1 312 ? 35.63100 18.97800 43.59000  1.000 73.12000  ?  854  ARG AAZA CG  1 
ATOM   2128 C CD  . ARG A 1 312 ? 34.95200 17.70100 43.16300  1.000 78.94000  ?  854  ARG AAZA CD  1 
ATOM   2129 N NE  . ARG A 1 312 ? 35.00700 17.53000 41.71800  1.000 81.59000  ?  854  ARG AAZA NE  1 
ATOM   2130 C CZ  . ARG A 1 312 ? 36.03800 16.98300 41.08700  1.000 81.70000  ?  854  ARG AAZA CZ  1 
ATOM   2131 N NH1 . ARG A 1 312 ? 37.11400 16.58300 41.74200  1.000 80.40000  ?  854  ARG AAZA NH1 1 
ATOM   2132 N NH2 . ARG A 1 312 ? 35.99600 16.84400 39.76700  1.000 80.57000  ?  854  ARG AAZA NH2 1 
ATOM   2133 N N   . ILE A 1 313 ? 33.96100 22.55800 45.08500  1.000 78.27000  ?  855  ILE AAZA N   1 
ATOM   2134 C CA  . ILE A 1 313 ? 34.21000 23.25600 46.34400  1.000 74.19000  ?  855  ILE AAZA CA  1 
ATOM   2135 C C   . ILE A 1 313 ? 33.00000 23.14900 47.26800  1.000 76.35000  ?  855  ILE AAZA C   1 
ATOM   2136 O O   . ILE A 1 313 ? 33.14700 22.82700 48.45200  1.000 78.54000  ?  855  ILE AAZA O   1 
ATOM   2137 C CB  . ILE A 1 313 ? 34.61000 24.71700 46.09100  1.000 70.01000  ?  855  ILE AAZA CB  1 
ATOM   2138 C CG1 . ILE A 1 313 ? 35.86600 24.80000 45.21200  1.000 68.80000  ?  855  ILE AAZA CG1 1 
ATOM   2139 C CG2 . ILE A 1 313 ? 34.87100 25.40200 47.39400  1.000 68.45000  ?  855  ILE AAZA CG2 1 
ATOM   2140 C CD1 . ILE A 1 313 ? 36.38300 26.22400 45.00200  1.000 59.34000  ?  855  ILE AAZA CD1 1 
ATOM   2141 N N   . ILE A 1 314 ? 31.78600 23.39000 46.74300  1.000 75.30000  ?  856  ILE AAZA N   1 
ATOM   2142 C CA  . ILE A 1 314 ? 30.55900 23.16800 47.52400  1.000 74.71000  ?  856  ILE AAZA CA  1 
ATOM   2143 C C   . ILE A 1 314 ? 30.48000 21.74200 48.05200  1.000 79.97000  ?  856  ILE AAZA C   1 
ATOM   2144 O O   . ILE A 1 314 ? 30.03100 21.49900 49.18300  1.000 84.62000  ?  856  ILE AAZA O   1 
ATOM   2145 C CB  . ILE A 1 314 ? 29.31000 23.52600 46.69600  1.000 74.89000  ?  856  ILE AAZA CB  1 
ATOM   2146 C CG1 . ILE A 1 314 ? 29.33700 25.00900 46.29600  1.000 75.24000  ?  856  ILE AAZA CG1 1 
ATOM   2147 C CG2 . ILE A 1 314 ? 28.03300 23.10200 47.40100  1.000 73.71000  ?  856  ILE AAZA CG2 1 
ATOM   2148 C CD1 . ILE A 1 314 ? 28.20600 25.43200 45.41500  1.000 69.99000  ?  856  ILE AAZA CD1 1 
ATOM   2149 N N   . GLU A 1 315 ? 30.92200 20.77400 47.25700  1.000 83.23000  ?  857  GLU AAZA N   1 
ATOM   2150 C CA  . GLU A 1 315 ? 30.95900 19.40500 47.75800  1.000 86.29000  ?  857  GLU AAZA CA  1 
ATOM   2151 C C   . GLU A 1 315 ? 31.92900 19.25600 48.92000  1.000 78.59000  ?  857  GLU AAZA C   1 
ATOM   2152 O O   . GLU A 1 315 ? 31.62000 18.58600 49.90600  1.000 80.57000  ?  857  GLU AAZA O   1 
ATOM   2153 C CB  . GLU A 1 315 ? 31.32700 18.44600 46.63200  1.000 88.53000  ?  857  GLU AAZA CB  1 
ATOM   2154 C CG  . GLU A 1 315 ? 30.21400 18.25500 45.63000  1.000 89.80000  ?  857  GLU AAZA CG  1 
ATOM   2155 C CD  . GLU A 1 315 ? 30.67500 17.42600 44.46300  1.000 98.34000  ?  857  GLU AAZA CD  1 
ATOM   2156 O OE1 . GLU A 1 315 ? 31.63700 16.64100 44.67000  1.000 98.06000  ?  857  GLU AAZA OE1 1 
ATOM   2157 O OE2 . GLU A 1 315 ? 30.11600 17.58900 43.34400  1.000 101.73000 ?  857  GLU AAZA OE2 1 
ATOM   2158 N N   . ILE A 1 316 ? 33.10900 19.86400 48.80800  1.000 78.81000  ?  858  ILE AAZA N   1 
ATOM   2159 C CA  . ILE A 1 316 ? 34.06800 19.82500 49.95100  1.000 78.66000  ?  858  ILE AAZA CA  1 
ATOM   2160 C C   . ILE A 1 316 ? 33.33600 20.40400 51.15900  1.000 79.87000  ?  858  ILE AAZA C   1 
ATOM   2161 O O   . ILE A 1 316 ? 33.26500 19.71900 52.19000  1.000 73.65000  ?  858  ILE AAZA O   1 
ATOM   2162 C CB  . ILE A 1 316 ? 35.35700 20.59300 49.61000  1.000 30.00000  ?  858  ILE AAZA CB  1 
ATOM   2163 C CG1 . ILE A 1 316 ? 36.10100 19.94300 48.44200  1.000 30.00000  ?  858  ILE AAZA CG1 1 
ATOM   2164 C CG2 . ILE A 1 316 ? 36.24300 20.72500 50.83500  1.000 30.00000  ?  858  ILE AAZA CG2 1 
ATOM   2165 C CD1 . ILE A 1 316 ? 37.19300 20.80400 47.86100  1.000 30.00000  ?  858  ILE AAZA CD1 1 
ATOM   2166 N N   . LEU A 1 317 ? 32.80500 21.61600 51.02300  1.000 80.54000  ?  859  LEU AAZA N   1 
ATOM   2167 C CA  . LEU A 1 317 ? 32.00300 22.21100 52.08600  1.000 77.92000  ?  859  LEU AAZA CA  1 
ATOM   2168 C C   . LEU A 1 317 ? 31.14300 21.14200 52.74200  1.000 81.75000  ?  859  LEU AAZA C   1 
ATOM   2169 O O   . LEU A 1 317 ? 31.19400 20.95600 53.96000  1.000 80.18000  ?  859  LEU AAZA O   1 
ATOM   2170 C CB  . LEU A 1 317 ? 31.12800 23.33400 51.52200  1.000 74.46000  ?  859  LEU AAZA CB  1 
ATOM   2171 C CG  . LEU A 1 317 ? 30.68400 24.51000 52.38900  1.000 74.99000  ?  859  LEU AAZA CG  1 
ATOM   2172 C CD1 . LEU A 1 317 ? 29.80100 25.40500 51.57200  1.000 80.69000  ?  859  LEU AAZA CD1 1 
ATOM   2173 C CD2 . LEU A 1 317 ? 29.92900 24.06600 53.59500  1.000 79.18000  ?  859  LEU AAZA CD2 1 
ATOM   2174 N N   . GLN A 1 318 ? 30.34100 20.42900 51.94100  1.000 83.91000  ?  860  GLN AAZA N   1 
ATOM   2175 C CA  . GLN A 1 318 ? 29.47700 19.35000 52.41700  1.000 88.78000  ?  860  GLN AAZA CA  1 
ATOM   2176 C C   . GLN A 1 318 ? 30.18700 18.35400 53.42600  1.000 81.86000  ?  860  GLN AAZA C   1 
ATOM   2177 O O   . GLN A 1 318 ? 29.67500 18.14200 54.52800  1.000 79.59000  ?  860  GLN AAZA O   1 
ATOM   2178 C CB  . GLN A 1 318 ? 29.07400 18.43100 51.28900  1.000 89.82000  ?  860  GLN AAZA CB  1 
ATOM   2179 C CG  . GLN A 1 318 ? 27.74400 18.74300 50.69400  1.000 90.54000  ?  860  GLN AAZA CG  1 
ATOM   2180 C CD  . GLN A 1 318 ? 27.07200 17.46900 50.26000  1.000 96.80000  ?  860  GLN AAZA CD  1 
ATOM   2181 O OE1 . GLN A 1 318 ? 27.11400 17.08800 49.08800  1.000 104.86000 ?  860  GLN AAZA OE1 1 
ATOM   2182 N NE2 . GLN A 1 318 ? 26.48000 16.77500 51.21600  1.000 92.53000  ?  860  GLN AAZA NE2 1 
ATOM   2183 N N   . VAL A 1 319 ? 31.31400 17.76400 53.02700  1.000 75.12000  ?  861  VAL AAZA N   1 
ATOM   2184 C CA  . VAL A 1 319 ? 32.02400 16.92700 53.89700  1.000 82.08000  ?  861  VAL AAZA CA  1 
ATOM   2185 C C   . VAL A 1 319 ? 32.54900 17.73300 55.11000  1.000 85.37000  ?  861  VAL AAZA C   1 
ATOM   2186 O O   . VAL A 1 319 ? 32.57100 17.25800 56.25800  1.000 79.78000  ?  861  VAL AAZA O   1 
ATOM   2187 C CB  . VAL A 1 319 ? 33.25300 16.28400 53.14500  1.000 80.49000  ?  861  VAL AAZA CB  1 
ATOM   2188 C CG1 . VAL A 1 319 ? 34.10700 15.43400 54.04000  1.000 77.55000  ?  861  VAL AAZA CG1 1 
ATOM   2189 C CG2 . VAL A 1 319 ? 32.71300 15.45400 52.03700  1.000 82.04000  ?  861  VAL AAZA CG2 1 
ATOM   2190 N N   . PHE A 1 320 ? 32.89500 18.98800 54.84700  1.000 85.65000  ?  862  PHE AAZA N   1 
ATOM   2191 C CA  . PHE A 1 320 ? 33.33800 19.87500 55.94800  1.000 79.44000  ?  862  PHE AAZA CA  1 
ATOM   2192 C C   . PHE A 1 320 ? 32.21700 19.94200 56.98500  1.000 77.72000  ?  862  PHE AAZA C   1 
ATOM   2193 O O   . PHE A 1 320 ? 32.48900 19.72400 58.17300  1.000 77.70000  ?  862  PHE AAZA O   1 
ATOM   2194 C CB  . PHE A 1 320 ? 33.71600 21.24700 55.39100  1.000 81.71000  ?  862  PHE AAZA CB  1 
ATOM   2195 C CG  . PHE A 1 320 ? 35.18500 21.44500 55.12700  1.000 78.53000  ?  862  PHE AAZA CG  1 
ATOM   2196 C CD1 . PHE A 1 320 ? 36.12000 20.55300 55.62300  1.000 74.56000  ?  862  PHE AAZA CD1 1 
ATOM   2197 C CD2 . PHE A 1 320 ? 35.63500 22.54000 54.41000  1.000 75.94000  ?  862  PHE AAZA CD2 1 
ATOM   2198 C CE1 . PHE A 1 320 ? 37.47200 20.74300 55.38900  1.000 71.04000  ?  862  PHE AAZA CE1 1 
ATOM   2199 C CE2 . PHE A 1 320 ? 36.98700 22.72400 54.17100  1.000 78.99000  ?  862  PHE AAZA CE2 1 
ATOM   2200 C CZ  . PHE A 1 320 ? 37.90300 21.82700 54.66300  1.000 75.29000  ?  862  PHE AAZA CZ  1 
ATOM   2201 N N   . GLN A 1 321 ? 30.99200 20.22100 56.53500  1.000 78.79000  ?  863  GLN AAZA N   1 
ATOM   2202 C CA  . GLN A 1 321 ? 29.86700 20.32600 57.47300  1.000 81.94000  ?  863  GLN AAZA CA  1 
ATOM   2203 C C   . GLN A 1 321 ? 29.56400 18.97900 58.12600  1.000 85.58000  ?  863  GLN AAZA C   1 
ATOM   2204 O O   . GLN A 1 321 ? 29.04400 18.93700 59.24800  1.000 82.33000  ?  863  GLN AAZA O   1 
ATOM   2205 C CB  . GLN A 1 321 ? 28.60200 20.87400 56.78200  1.000 76.16000  ?  863  GLN AAZA CB  1 
ATOM   2206 C CG  . GLN A 1 321 ? 28.36200 22.40600 56.93900  1.000 84.42000  ?  863  GLN AAZA CG  1 
ATOM   2207 C CD  . GLN A 1 321 ? 27.01600 22.95500 56.32700  1.000 101.50000 ?  863  GLN AAZA CD  1 
ATOM   2208 O OE1 . GLN A 1 321 ? 26.60400 22.59000 55.19800  1.000 94.96000  ?  863  GLN AAZA OE1 1 
ATOM   2209 N NE2 . GLN A 1 321 ? 26.38000 23.89600 57.05400  1.000 94.69000  ?  863  GLN AAZA NE2 1 
ATOM   2210 N N   . GLU A 1 322 ? 29.89700 17.87400 57.44800  1.000 87.75000  ?  864  GLU AAZA N   1 
ATOM   2211 C CA  . GLU A 1 322 ? 29.70700 16.54500 58.02600  1.000 84.98000  ?  864  GLU AAZA CA  1 
ATOM   2212 C C   . GLU A 1 322 ? 30.70200 16.27600 59.15000  1.000 84.65000  ?  864  GLU AAZA C   1 
ATOM   2213 O O   . GLU A 1 322 ? 30.37000 15.60500 60.13800  1.000 82.14000  ?  864  GLU AAZA O   1 
ATOM   2214 C CB  . GLU A 1 322 ? 29.84400 15.47700 56.93900  1.000 85.36000  ?  864  GLU AAZA CB  1 
ATOM   2215 C CG  . GLU A 1 322 ? 28.94500 15.65400 55.72200  1.000 91.11000  ?  864  GLU AAZA CG  1 
ATOM   2216 C CD  . GLU A 1 322 ? 29.06100 14.48200 54.73800  1.000 96.78000  ?  864  GLU AAZA CD  1 
ATOM   2217 O OE1 . GLU A 1 322 ? 30.07000 13.72800 54.84500  1.000 95.10000  ?  864  GLU AAZA OE1 1 
ATOM   2218 O OE2 . GLU A 1 322 ? 28.15200 14.31600 53.87500  1.000 91.88000  ?  864  GLU AAZA OE2 1 
ATOM   2219 N N   . LEU A 1 323 ? 31.93300 16.77200 59.00300  1.000 85.37000  ?  865  LEU AAZA N   1 
ATOM   2220 C CA  . LEU A 1 323 ? 33.00700 16.58900 59.97500  1.000 82.06000  ?  865  LEU AAZA CA  1 
ATOM   2221 C C   . LEU A 1 323 ? 32.97500 17.59300 61.12700  1.000 80.66000  ?  865  LEU AAZA C   1 
ATOM   2222 O O   . LEU A 1 323 ? 33.83200 17.51000 62.01200  1.000 75.88000  ?  865  LEU AAZA O   1 
ATOM   2223 C CB  . LEU A 1 323 ? 34.35000 16.68900 59.26100  1.000 77.45000  ?  865  LEU AAZA CB  1 
ATOM   2224 C CG  . LEU A 1 323 ? 34.66900 15.49100 58.39000  1.000 79.14000  ?  865  LEU AAZA CG  1 
ATOM   2225 C CD1 . LEU A 1 323 ? 35.72300 15.83500 57.32300  1.000 79.66000  ?  865  LEU AAZA CD1 1 
ATOM   2226 C CD2 . LEU A 1 323 ? 35.14300 14.35600 59.29300  1.000 72.58000  ?  865  LEU AAZA CD2 1 
ATOM   2227 N N   . ASN A 1 324 ? 32.03200 18.53400 61.14100  1.000 77.64000  ?  866  ASN AAZA N   1 
ATOM   2228 C CA  . ASN A 1 324 ? 32.05300 19.62000 62.10700  1.000 82.20000  ?  866  ASN AAZA CA  1 
ATOM   2229 C C   . ASN A 1 324 ? 33.39200 20.35600 62.10500  1.000 85.34000  ?  866  ASN AAZA C   1 
ATOM   2230 O O   . ASN A 1 324 ? 34.04800 20.53200 63.14400  1.000 86.67000  ?  866  ASN AAZA O   1 
ATOM   2231 C CB  . ASN A 1 324 ? 31.71600 19.10300 63.49700  1.000 87.46000  ?  866  ASN AAZA CB  1 
ATOM   2232 C CG  . ASN A 1 324 ? 30.30000 18.70000 63.60600  1.000 84.61000  ?  866  ASN AAZA CG  1 
ATOM   2233 O OD1 . ASN A 1 324 ? 29.46000 19.19200 62.85200  1.000 83.26000  ?  866  ASN AAZA OD1 1 
ATOM   2234 N ND2 . ASN A 1 324 ? 30.00100 17.81500 64.55300  1.000 86.59000  ?  866  ASN AAZA ND2 1 
ATOM   2235 N N   . ASN A 1 325 ? 33.79300 20.79900 60.91700  1.000 77.90000  ?  867  ASN AAZA N   1 
ATOM   2236 C CA  . ASN A 1 325 ? 34.93700 21.68800 60.76800  1.000 77.81000  ?  867  ASN AAZA CA  1 
ATOM   2237 C C   . ASN A 1 325 ? 34.39200 23.04200 60.33200  1.000 77.89000  ?  867  ASN AAZA C   1 
ATOM   2238 O O   . ASN A 1 325 ? 34.39100 23.38900 59.14600  1.000 78.19000  ?  867  ASN AAZA O   1 
ATOM   2239 C CB  . ASN A 1 325 ? 35.94400 21.16800 59.79100  1.000 79.55000  ?  867  ASN AAZA CB  1 
ATOM   2240 C CG  . ASN A 1 325 ? 37.10300 22.13300 59.59200  1.000 80.68000  ?  867  ASN AAZA CG  1 
ATOM   2241 O OD1 . ASN A 1 325 ? 37.28400 23.07500 60.37400  1.000 80.75000  ?  867  ASN AAZA OD1 1 
ATOM   2242 N ND2 . ASN A 1 325 ? 37.90100 21.89800 58.55500  1.000 80.73000  ?  867  ASN AAZA ND2 1 
ATOM   2243 N N   . PHE A 1 326 ? 33.93700 23.81900 61.31700  1.000 76.20000  ?  868  PHE AAZA N   1 
ATOM   2244 C CA  . PHE A 1 326 ? 33.36000 25.12200 61.02100  1.000 76.11000  ?  868  PHE AAZA CA  1 
ATOM   2245 C C   . PHE A 1 326 ? 34.39900 26.09200 60.48900  1.000 80.06000  ?  868  PHE AAZA C   1 
ATOM   2246 O O   . PHE A 1 326 ? 34.05400 27.01500 59.72900  1.000 78.48000  ?  868  PHE AAZA O   1 
ATOM   2247 C CB  . PHE A 1 326 ? 32.67500 25.67000 62.25700  1.000 69.16000  ?  868  PHE AAZA CB  1 
ATOM   2248 C CG  . PHE A 1 326 ? 31.55100 24.83100 62.69200  1.000 72.16000  ?  868  PHE AAZA CG  1 
ATOM   2249 C CD1 . PHE A 1 326 ? 30.32300 24.94100 62.07100  1.000 69.26000  ?  868  PHE AAZA CD1 1 
ATOM   2250 C CD2 . PHE A 1 326 ? 31.72100 23.88800 63.69500  1.000 82.76000  ?  868  PHE AAZA CD2 1 
ATOM   2251 C CE1 . PHE A 1 326 ? 29.26600 24.14400 62.45400  1.000 76.35000  ?  868  PHE AAZA CE1 1 
ATOM   2252 C CE2 . PHE A 1 326 ? 30.66700 23.07800 64.09600  1.000 83.22000  ?  868  PHE AAZA CE2 1 
ATOM   2253 C CZ  . PHE A 1 326 ? 29.44000 23.20100 63.47500  1.000 83.75000  ?  868  PHE AAZA CZ  1 
ATOM   2254 N N   . ASN A 1 327 ? 35.66900 25.90100 60.85000  1.000 74.35000  ?  869  ASN AAZA N   1 
ATOM   2255 C CA  . ASN A 1 327 ? 36.68700 26.74000 60.25100  1.000 71.35000  ?  869  ASN AAZA CA  1 
ATOM   2256 C C   . ASN A 1 327 ? 36.72900 26.53800 58.74400  1.000 77.07000  ?  869  ASN AAZA C   1 
ATOM   2257 O O   . ASN A 1 327 ? 36.63100 27.49800 57.97500  1.000 79.52000  ?  869  ASN AAZA O   1 
ATOM   2258 C CB  . ASN A 1 327 ? 38.04000 26.46500 60.86500  1.000 72.02000  ?  869  ASN AAZA CB  1 
ATOM   2259 C CG  . ASN A 1 327 ? 39.03800 27.50300 60.45900  1.000 84.34000  ?  869  ASN AAZA CG  1 
ATOM   2260 O OD1 . ASN A 1 327 ? 39.52200 27.48600 59.31000  1.000 78.41000  ?  869  ASN AAZA OD1 1 
ATOM   2261 N ND2 . ASN A 1 327 ? 39.30400 28.47200 61.36200  1.000 85.04000  ?  869  ASN AAZA ND2 1 
ATOM   2262 N N   . GLY A 1 328 ? 36.83700 25.28700 58.30400  1.000 77.28000  ?  870  GLY AAZA N   1 
ATOM   2263 C CA  . GLY A 1 328 ? 36.87900 25.01600 56.88000  1.000 75.56000  ?  870  GLY AAZA CA  1 
ATOM   2264 C C   . GLY A 1 328 ? 35.58800 25.35100 56.17100  1.000 75.78000  ?  870  GLY AAZA C   1 
ATOM   2265 O O   . GLY A 1 328 ? 35.60700 25.73100 54.99400  1.000 75.35000  ?  870  GLY AAZA O   1 
ATOM   2266 N N   . VAL A 1 329 ? 34.45200 25.20400 56.86100  1.000 73.75000  ?  871  VAL AAZA N   1 
ATOM   2267 C CA  . VAL A 1 329 ? 33.18500 25.66600 56.29400  1.000 78.53000  ?  871  VAL AAZA CA  1 
ATOM   2268 C C   . VAL A 1 329 ? 33.25200 27.16400 55.99000  1.000 75.47000  ?  871  VAL AAZA C   1 
ATOM   2269 O O   . VAL A 1 329 ? 32.81800 27.62300 54.91900  1.000 72.90000  ?  871  VAL AAZA O   1 
ATOM   2270 C CB  . VAL A 1 329 ? 32.01600 25.30900 57.23700  1.000 75.36000  ?  871  VAL AAZA CB  1 
ATOM   2271 C CG1 . VAL A 1 329 ? 30.70900 25.94500 56.77500  1.000 72.23000  ?  871  VAL AAZA CG1 1 
ATOM   2272 C CG2 . VAL A 1 329 ? 31.84900 23.82100 57.27600  1.000 70.85000  ?  871  VAL AAZA CG2 1 
ATOM   2273 N N   . LEU A 1 330 ? 33.83500 27.94300 56.90100  1.000 72.23000  ?  872  LEU AAZA N   1 
ATOM   2274 C CA  . LEU A 1 330 ? 33.91100 29.38000 56.67400  1.000 71.60000  ?  872  LEU AAZA CA  1 
ATOM   2275 C C   . LEU A 1 330 ? 34.98900 29.77700 55.68200  1.000 66.68000  ?  872  LEU AAZA C   1 
ATOM   2276 O O   . LEU A 1 330 ? 34.85700 30.82500 55.05300  1.000 67.31000  ?  872  LEU AAZA O   1 
ATOM   2277 C CB  . LEU A 1 330 ? 34.13100 30.10900 57.98500  1.000 75.72000  ?  872  LEU AAZA CB  1 
ATOM   2278 C CG  . LEU A 1 330 ? 32.87300 30.02800 58.83300  1.000 71.54000  ?  872  LEU AAZA CG  1 
ATOM   2279 C CD1 . LEU A 1 330 ? 33.10600 30.87900 60.04800  1.000 73.18000  ?  872  LEU AAZA CD1 1 
ATOM   2280 C CD2 . LEU A 1 330 ? 31.65300 30.50300 58.04500  1.000 67.73000  ?  872  LEU AAZA CD2 1 
ATOM   2281 N N   . GLU A 1 331 ? 36.05900 28.99000 55.53200  1.000 69.80000  ?  873  GLU AAZA N   1 
ATOM   2282 C CA  . GLU A 1 331 ? 37.00400 29.23800 54.44100  1.000 68.91000  ?  873  GLU AAZA CA  1 
ATOM   2283 C C   . GLU A 1 331 ? 36.27000 29.28600 53.12000  1.000 70.52000  ?  873  GLU AAZA C   1 
ATOM   2284 O O   . GLU A 1 331 ? 36.49800 30.17700 52.29000  1.000 69.85000  ?  873  GLU AAZA O   1 
ATOM   2285 C CB  . GLU A 1 331 ? 38.06400 28.14800 54.37300  1.000 65.89000  ?  873  GLU AAZA CB  1 
ATOM   2286 C CG  . GLU A 1 331 ? 38.80700 27.91400 55.63900  1.000 77.09000  ?  873  GLU AAZA CG  1 
ATOM   2287 C CD  . GLU A 1 331 ? 39.88700 26.85500 55.47700  1.000 85.93000  ?  873  GLU AAZA CD  1 
ATOM   2288 O OE1 . GLU A 1 331 ? 39.71100 25.97200 54.58500  1.000 79.46000  ?  873  GLU AAZA OE1 1 
ATOM   2289 O OE2 . GLU A 1 331 ? 40.88100 26.88800 56.26300  1.000 82.92000  ?  873  GLU AAZA OE2 1 
ATOM   2290 N N   . VAL A 1 332 ? 35.36600 28.32700 52.92100  1.000 68.89000  ?  874  VAL AAZA N   1 
ATOM   2291 C CA  . VAL A 1 332 ? 34.61300 28.24800 51.68000  1.000 66.72000  ?  874  VAL AAZA CA  1 
ATOM   2292 C C   . VAL A 1 332 ? 33.58600 29.36700 51.59400  1.000 68.60000  ?  874  VAL AAZA C   1 
ATOM   2293 O O   . VAL A 1 332 ? 33.45000 30.01600 50.54900  1.000 68.19000  ?  874  VAL AAZA O   1 
ATOM   2294 C CB  . VAL A 1 332 ? 33.96000 26.86900 51.54500  1.000 67.11000  ?  874  VAL AAZA CB  1 
ATOM   2295 C CG1 . VAL A 1 332 ? 33.25600 26.78000 50.23900  1.000 68.11000  ?  874  VAL AAZA CG1 1 
ATOM   2296 C CG2 . VAL A 1 332 ? 35.02800 25.81700 51.60600  1.000 69.68000  ?  874  VAL AAZA CG2 1 
ATOM   2297 N N   . VAL A 1 333 ? 32.84100 29.61300 52.67200  1.000 64.90000  ?  875  VAL AAZA N   1 
ATOM   2298 C CA  . VAL A 1 333 ? 31.85400 30.68600 52.59500  1.000 66.83000  ?  875  VAL AAZA CA  1 
ATOM   2299 C C   . VAL A 1 333 ? 32.52800 32.02300 52.26000  1.000 68.82000  ?  875  VAL AAZA C   1 
ATOM   2300 O O   . VAL A 1 333 ? 32.04900 32.76800 51.39200  1.000 65.27000  ?  875  VAL AAZA O   1 
ATOM   2301 C CB  . VAL A 1 333 ? 31.01200 30.74300 53.88100  1.000 66.00000  ?  875  VAL AAZA CB  1 
ATOM   2302 C CG1 . VAL A 1 333 ? 30.27200 32.05900 53.99400  1.000 68.50000  ?  875  VAL AAZA CG1 1 
ATOM   2303 C CG2 . VAL A 1 333 ? 30.01800 29.63000 53.85300  1.000 68.74000  ?  875  VAL AAZA CG2 1 
ATOM   2304 N N   . SER A 1 334 ? 33.67200 32.32700 52.89400  1.000 67.45000  ?  876  SER AAZA N   1 
ATOM   2305 C CA  . SER A 1 334 ? 34.37900 33.56400 52.56800  1.000 61.84000  ?  876  SER AAZA CA  1 
ATOM   2306 C C   . SER A 1 334 ? 34.80400 33.58500 51.11600  1.000 63.72000  ?  876  SER AAZA C   1 
ATOM   2307 O O   . SER A 1 334 ? 34.64700 34.60400 50.43400  1.000 66.26000  ?  876  SER AAZA O   1 
ATOM   2308 C CB  . SER A 1 334 ? 35.60100 33.76000 53.44700  1.000 61.62000  ?  876  SER AAZA CB  1 
ATOM   2309 O OG  . SER A 1 334 ? 35.24200 33.81500 54.78800  1.000 68.10000  ?  876  SER AAZA OG  1 
ATOM   2310 N N   . ALA A 1 335 ? 35.38600 32.48500 50.63300  1.000 63.59000  ?  877  ALA AAZA N   1 
ATOM   2311 C CA  . ALA A 1 335 ? 35.72700 32.40700 49.21700  1.000 65.14000  ?  877  ALA AAZA CA  1 
ATOM   2312 C C   . ALA A 1 335 ? 34.53000 32.80900 48.38100  1.000 63.44000  ?  877  ALA AAZA C   1 
ATOM   2313 O O   . ALA A 1 335 ? 34.55700 33.81700 47.67700  1.000 64.38000  ?  877  ALA AAZA O   1 
ATOM   2314 C CB  . ALA A 1 335 ? 36.19800 31.00100 48.84300  1.000 62.87000  ?  877  ALA AAZA CB  1 
ATOM   2315 N N   . MET A 1 336 ? 33.43100 32.08300 48.53800  1.000 65.58000  ?  878  MET AAZA N   1 
ATOM   2316 C CA  . MET A 1 336 ? 32.21400 32.36400 47.79400  1.000 67.81000  ?  878  MET AAZA CA  1 
ATOM   2317 C C   . MET A 1 336 ? 31.67800 33.76700 48.00300  1.000 68.70000  ?  878  MET AAZA C   1 
ATOM   2318 O O   . MET A 1 336 ? 30.78700 34.17300 47.25200  1.000 68.93000  ?  878  MET AAZA O   1 
ATOM   2319 C CB  . MET A 1 336 ? 31.13100 31.37100 48.19100  1.000 72.00000  ?  878  MET AAZA CB  1 
ATOM   2320 C CG  . MET A 1 336 ? 31.52400 29.95000 47.93700  1.000 72.81000  ?  878  MET AAZA CG  1 
ATOM   2321 S SD  . MET A 1 336 ? 31.60700 29.59900 46.16300  1.000 71.67000  ?  878  MET AAZA SD  1 
ATOM   2322 C CE  . MET A 1 336 ? 32.60600 28.11500 46.29300  1.000 69.89000  ?  878  MET AAZA CE  1 
ATOM   2323 N N   . ASN A 1 337 ? 32.15100 34.50500 49.01200  1.000 69.98000  ?  879  ASN AAZA N   1 
ATOM   2324 C CA  . ASN A 1 337 ? 31.61800 35.83900 49.26300  1.000 68.75000  ?  879  ASN AAZA CA  1 
ATOM   2325 C C   . ASN A 1 337 ? 32.52100 36.95000 48.77100  1.000 64.55000  ?  879  ASN AAZA C   1 
ATOM   2326 O O   . ASN A 1 337 ? 32.06900 38.09400 48.68300  1.000 63.71000  ?  879  ASN AAZA O   1 
ATOM   2327 C CB  . ASN A 1 337 ? 31.34900 36.05000 50.74800  1.000 65.92000  ?  879  ASN AAZA CB  1 
ATOM   2328 C CG  . ASN A 1 337 ? 29.97300 35.63700 51.12300  1.000 67.52000  ?  879  ASN AAZA CG  1 
ATOM   2329 O OD1 . ASN A 1 337 ? 29.01400 36.30900 50.78000  1.000 73.20000  ?  879  ASN AAZA OD1 1 
ATOM   2330 N ND2 . ASN A 1 337 ? 29.85600 34.54300 51.84900  1.000 69.79000  ?  879  ASN AAZA ND2 1 
ATOM   2331 N N   . SER A 1 338 ? 33.76700 36.63800 48.44200  1.000 64.90000  ?  880  SER AAZA N   1 
ATOM   2332 C CA  . SER A 1 338 ? 34.69400 37.65200 47.97700  1.000 67.55000  ?  880  SER AAZA CA  1 
ATOM   2333 C C   . SER A 1 338 ? 34.12400 38.38400 46.78400  1.000 67.18000  ?  880  SER AAZA C   1 
ATOM   2334 O O   . SER A 1 338 ? 33.28800 37.87100 46.03900  1.000 64.90000  ?  880  SER AAZA O   1 
ATOM   2335 C CB  . SER A 1 338 ? 36.02900 37.03500 47.59200  1.000 67.56000  ?  880  SER AAZA CB  1 
ATOM   2336 O OG  . SER A 1 338 ? 35.85600 35.76300 47.00300  1.000 67.14000  ?  880  SER AAZA OG  1 
ATOM   2337 N N   . SER A 1 339 ? 34.58300 39.61400 46.61300  1.000 69.53000  ?  881  SER AAZA N   1 
ATOM   2338 C CA  . SER A 1 339 ? 34.06000 40.40700 45.51200  1.000 72.31000  ?  881  SER AAZA CA  1 
ATOM   2339 C C   . SER A 1 339 ? 34.43500 39.87100 44.12500  1.000 71.38000  ?  881  SER AAZA C   1 
ATOM   2340 O O   . SER A 1 339 ? 33.69100 40.17900 43.18100  1.000 71.72000  ?  881  SER AAZA O   1 
ATOM   2341 C CB  . SER A 1 339 ? 34.44300 41.88500 45.73000  1.000 69.19000  ?  881  SER AAZA CB  1 
ATOM   2342 O OG  . SER A 1 339 ? 35.79500 42.02300 46.11800  1.000 73.19000  ?  881  SER AAZA OG  1 
ATOM   2343 N N   . PRO A 1 340 ? 35.50800 39.02600 43.91800  1.000 72.12000  ?  882  PRO AAZA N   1 
ATOM   2344 C CA  . PRO A 1 340 ? 35.63700 38.34600 42.61900  1.000 65.45000  ?  882  PRO AAZA CA  1 
ATOM   2345 C C   . PRO A 1 340 ? 34.61000 37.24500 42.42000  1.000 68.68000  ?  882  PRO AAZA C   1 
ATOM   2346 O O   . PRO A 1 340 ? 33.97600 37.18000 41.37000  1.000 66.95000  ?  882  PRO AAZA O   1 
ATOM   2347 C CB  . PRO A 1 340 ? 37.04100 37.73900 42.67100  1.000 63.48000  ?  882  PRO AAZA CB  1 
ATOM   2348 C CG  . PRO A 1 340 ? 37.76200 38.50400 43.63300  1.000 66.27000  ?  882  PRO AAZA CG  1 
ATOM   2349 C CD  . PRO A 1 340 ? 36.76500 38.89300 44.68600  1.000 71.71000  ?  882  PRO AAZA CD  1 
ATOM   2350 N N   . VAL A 1 341 ? 34.45900 36.36000 43.41400  1.000 71.53000  ?  883  VAL AAZA N   1 
ATOM   2351 C CA  . VAL A 1 341 ? 33.64100 35.15800 43.24400  1.000 68.03000  ?  883  VAL AAZA CA  1 
ATOM   2352 C C   . VAL A 1 341 ? 32.15300 35.48200 43.25300  1.000 72.23000  ?  883  VAL AAZA C   1 
ATOM   2353 O O   . VAL A 1 341 ? 31.38000 34.89400 42.49300  1.000 76.20000  ?  883  VAL AAZA O   1 
ATOM   2354 C CB  . VAL A 1 341 ? 33.98100 34.12500 44.32400  1.000 65.36000  ?  883  VAL AAZA CB  1 
ATOM   2355 C CG1 . VAL A 1 341 ? 33.00200 32.97300 44.26900  1.000 65.99000  ?  883  VAL AAZA CG1 1 
ATOM   2356 C CG2 . VAL A 1 341 ? 35.39600 33.63100 44.13500  1.000 69.45000  ?  883  VAL AAZA CG2 1 
ATOM   2357 N N   . TYR A 1 342 ? 31.72500 36.41300 44.10900  1.000 73.36000  ?  884  TYR AAZA N   1 
ATOM   2358 C CA  . TYR A 1 342 ? 30.29900 36.67700 44.30100  1.000 70.64000  ?  884  TYR AAZA CA  1 
ATOM   2359 C C   . TYR A 1 342 ? 29.61500 37.18700 43.03100  1.000 71.40000  ?  884  TYR AAZA C   1 
ATOM   2360 O O   . TYR A 1 342 ? 28.42900 36.91000 42.82200  1.000 78.25000  ?  884  TYR AAZA O   1 
ATOM   2361 C CB  . TYR A 1 342 ? 30.14400 37.66600 45.45800  1.000 67.94000  ?  884  TYR AAZA CB  1 
ATOM   2362 C CG  . TYR A 1 342 ? 28.75900 37.93500 46.01200  1.000 67.60000  ?  884  TYR AAZA CG  1 
ATOM   2363 C CD1 . TYR A 1 342 ? 28.20400 37.10700 46.96600  1.000 70.84000  ?  884  TYR AAZA CD1 1 
ATOM   2364 C CD2 . TYR A 1 342 ? 28.06100 39.08500 45.67100  1.000 67.86000  ?  884  TYR AAZA CD2 1 
ATOM   2365 C CE1 . TYR A 1 342 ? 26.95500 37.37700 47.50600  1.000 78.97000  ?  884  TYR AAZA CE1 1 
ATOM   2366 C CE2 . TYR A 1 342 ? 26.81500 39.37000 46.21700  1.000 69.40000  ?  884  TYR AAZA CE2 1 
ATOM   2367 C CZ  . TYR A 1 342 ? 26.26500 38.51600 47.13200  1.000 76.29000  ?  884  TYR AAZA CZ  1 
ATOM   2368 O OH  . TYR A 1 342 ? 25.02200 38.77400 47.69000  1.000 78.88000  ?  884  TYR AAZA OH  1 
ATOM   2369 N N   . ARG A 1 343 ? 30.33600 37.89900 42.16200  1.000 66.15000  ?  885  ARG AAZA N   1 
ATOM   2370 C CA  . ARG A 1 343 ? 29.70800 38.55900 41.02000  1.000 73.80000  ?  885  ARG AAZA CA  1 
ATOM   2371 C C   . ARG A 1 343 ? 29.45400 37.64400 39.82000  1.000 76.47000  ?  885  ARG AAZA C   1 
ATOM   2372 O O   . ARG A 1 343 ? 28.80100 38.06800 38.86500  1.000 76.93000  ?  885  ARG AAZA O   1 
ATOM   2373 C CB  . ARG A 1 343 ? 30.56700 39.73500 40.57300  1.000 70.70000  ?  885  ARG AAZA CB  1 
ATOM   2374 C CG  . ARG A 1 343 ? 31.91300 39.34200 40.03800  1.000 66.85000  ?  885  ARG AAZA CG  1 
ATOM   2375 C CD  . ARG A 1 343 ? 32.59800 40.53700 39.51900  1.000 62.69000  ?  885  ARG AAZA CD  1 
ATOM   2376 N NE  . ARG A 1 343 ? 31.77500 41.06500 38.45500  1.000 74.14000  ?  885  ARG AAZA NE  1 
ATOM   2377 C CZ  . ARG A 1 343 ? 31.93300 40.76100 37.17800  1.000 78.70000  ?  885  ARG AAZA CZ  1 
ATOM   2378 N NH1 . ARG A 1 343 ? 32.93500 39.99800 36.76900  1.000 73.57000  ?  885  ARG AAZA NH1 1 
ATOM   2379 N NH2 . ARG A 1 343 ? 31.06000 41.23100 36.29200  1.000 79.64000  ?  885  ARG AAZA NH2 1 
ATOM   2380 N N   . LEU A 1 344 ? 29.93900 36.40900 39.83600  1.000 73.07000  ?  886  LEU AAZA N   1 
ATOM   2381 C CA  . LEU A 1 344 ? 29.84700 35.52400 38.68300  1.000 72.72000  ?  886  LEU AAZA CA  1 
ATOM   2382 C C   . LEU A 1 344 ? 28.44300 34.93600 38.63000  1.000 82.58000  ?  886  LEU AAZA C   1 
ATOM   2383 O O   . LEU A 1 344 ? 28.20800 33.79600 39.04500  1.000 86.45000  ?  886  LEU AAZA O   1 
ATOM   2384 C CB  . LEU A 1 344 ? 30.88600 34.41600 38.79200  1.000 68.43000  ?  886  LEU AAZA CB  1 
ATOM   2385 C CG  . LEU A 1 344 ? 32.29000 34.81200 39.21400  1.000 64.79000  ?  886  LEU AAZA CG  1 
ATOM   2386 C CD1 . LEU A 1 344 ? 33.05600 33.58700 39.56400  1.000 62.52000  ?  886  LEU AAZA CD1 1 
ATOM   2387 C CD2 . LEU A 1 344 ? 32.98500 35.59300 38.11800  1.000 64.81000  ?  886  LEU AAZA CD2 1 
ATOM   2388 N N   . ASP A 1 345 ? 27.48300 35.71200 38.10100  1.000 81.73000  ?  887  ASP AAZA N   1 
ATOM   2389 C CA  . ASP A 1 345 ? 26.10900 35.20200 38.08200  1.000 80.91000  ?  887  ASP AAZA CA  1 
ATOM   2390 C C   . ASP A 1 345 ? 25.97600 33.98700 37.16900  1.000 82.64000  ?  887  ASP AAZA C   1 
ATOM   2391 O O   . ASP A 1 345 ? 25.36900 32.98400 37.56100  1.000 79.88000  ?  887  ASP AAZA O   1 
ATOM   2392 C CB  . ASP A 1 345 ? 25.11600 36.29200 37.69400  1.000 84.35000  ?  887  ASP AAZA CB  1 
ATOM   2393 C CG  . ASP A 1 345 ? 24.75300 37.19500 38.86200  1.000 89.89000  ?  887  ASP AAZA CG  1 
ATOM   2394 O OD1 . ASP A 1 345 ? 24.58200 36.68200 39.98900  1.000 92.51000  ?  887  ASP AAZA OD1 1 
ATOM   2395 O OD2 . ASP A 1 345 ? 24.62200 38.42000 38.65400  1.000 92.46000  ?  887  ASP AAZA OD2 1 
ATOM   2396 N N   . HIS A 1 346 ? 26.57000 34.04300 35.96100  1.000 81.69000  ?  888  HIS AAZA N   1 
ATOM   2397 C CA  . HIS A 1 346 ? 26.48100 32.93000 35.01000  1.000 79.93000  ?  888  HIS AAZA CA  1 
ATOM   2398 C C   . HIS A 1 346 ? 26.93900 31.60500 35.62100  1.000 82.19000  ?  888  HIS AAZA C   1 
ATOM   2399 O O   . HIS A 1 346 ? 26.39900 30.54000 35.29500  1.000 83.90000  ?  888  HIS AAZA O   1 
ATOM   2400 C CB  . HIS A 1 346 ? 27.31900 33.22800 33.76100  1.000 75.63000  ?  888  HIS AAZA CB  1 
ATOM   2401 C CG  . HIS A 1 346 ? 26.82600 34.39000 32.95800  1.000 81.13000  ?  888  HIS AAZA CG  1 
ATOM   2402 N ND1 . HIS A 1 346 ? 25.48700 34.68600 32.81500  1.000 84.71000  ?  888  HIS AAZA ND1 1 
ATOM   2403 C CD2 . HIS A 1 346 ? 27.49800 35.34400 32.27000  1.000 78.50000  ?  888  HIS AAZA CD2 1 
ATOM   2404 C CE1 . HIS A 1 346 ? 25.35700 35.76600 32.06500  1.000 83.29000  ?  888  HIS AAZA CE1 1 
ATOM   2405 N NE2 . HIS A 1 346 ? 26.56200 36.19000 31.72800  1.000 77.46000  ?  888  HIS AAZA NE2 1 
ATOM   2406 N N   . THR A 1 347 ? 27.92900 31.64500 36.50600  1.000 76.77000  ?  889  THR AAZA N   1 
ATOM   2407 C CA  . THR A 1 347 ? 28.50900 30.41100 37.01300  1.000 75.22000  ?  889  THR AAZA CA  1 
ATOM   2408 C C   . THR A 1 347 ? 27.63200 29.76700 38.08300  1.000 82.45000  ?  889  THR AAZA C   1 
ATOM   2409 O O   . THR A 1 347 ? 27.56200 28.53500 38.17200  1.000 84.40000  ?  889  THR AAZA O   1 
ATOM   2410 C CB  . THR A 1 347 ? 29.90100 30.70000 37.56200  1.000 73.76000  ?  889  THR AAZA CB  1 
ATOM   2411 O OG1 . THR A 1 347 ? 30.68400 31.34100 36.54300  1.000 72.54000  ?  889  THR AAZA OG1 1 
ATOM   2412 C CG2 . THR A 1 347 ? 30.58500 29.40900 38.04200  1.000 67.59000  ?  889  THR AAZA CG2 1 
ATOM   2413 N N   . PHE A 1 348 ? 26.97200 30.57100 38.92000  1.000 79.32000  ?  890  PHE AAZA N   1 
ATOM   2414 C CA  . PHE A 1 348 ? 26.04700 30.00100 39.89000  1.000 77.62000  ?  890  PHE AAZA CA  1 
ATOM   2415 C C   . PHE A 1 348 ? 24.73400 29.58700 39.25800  1.000 80.71000  ?  890  PHE AAZA C   1 
ATOM   2416 O O   . PHE A 1 348 ? 24.05900 28.69100 39.78900  1.000 78.10000  ?  890  PHE AAZA O   1 
ATOM   2417 C CB  . PHE A 1 348 ? 25.76500 30.99400 41.01700  1.000 82.47000  ?  890  PHE AAZA CB  1 
ATOM   2418 C CG  . PHE A 1 348 ? 26.94900 31.28800 41.86800  1.000 76.78000  ?  890  PHE AAZA CG  1 
ATOM   2419 C CD1 . PHE A 1 348 ? 27.46000 30.31700 42.69800  1.000 71.10000  ?  890  PHE AAZA CD1 1 
ATOM   2420 C CD2 . PHE A 1 348 ? 27.53400 32.53900 41.85600  1.000 76.66000  ?  890  PHE AAZA CD2 1 
ATOM   2421 C CE1 . PHE A 1 348 ? 28.54400 30.58200 43.48000  1.000 73.91000  ?  890  PHE AAZA CE1 1 
ATOM   2422 C CE2 . PHE A 1 348 ? 28.61700 32.81500 42.64500  1.000 73.29000  ?  890  PHE AAZA CE2 1 
ATOM   2423 C CZ  . PHE A 1 348 ? 29.12600 31.83800 43.45300  1.000 73.18000  ?  890  PHE AAZA CZ  1 
ATOM   2424 N N   . GLU A 1 349 ? 24.37000 30.22700 38.14000  1.000 80.12000  ?  891  GLU AAZA N   1 
ATOM   2425 C CA  . GLU A 1 349 ? 23.13600 29.91900 37.42900  1.000 82.05000  ?  891  GLU AAZA CA  1 
ATOM   2426 C C   . GLU A 1 349 ? 23.02700 28.43800 37.08600  1.000 85.14000  ?  891  GLU AAZA C   1 
ATOM   2427 O O   . GLU A 1 349 ? 21.90600 27.92400 36.94700  1.000 84.56000  ?  891  GLU AAZA O   1 
ATOM   2428 C CB  . GLU A 1 349 ? 23.06100 30.75200 36.15200  1.000 83.89000  ?  891  GLU AAZA CB  1 
ATOM   2429 C CG  . GLU A 1 349 ? 21.66400 30.99100 35.63800  1.000 93.38000  ?  891  GLU AAZA CG  1 
ATOM   2430 C CD  . GLU A 1 349 ? 21.48700 32.38800 35.03200  1.000 110.17000 ?  891  GLU AAZA CD  1 
ATOM   2431 O OE1 . GLU A 1 349 ? 22.42500 32.90800 34.35400  1.000 99.32000  ?  891  GLU AAZA OE1 1 
ATOM   2432 O OE2 . GLU A 1 349 ? 20.40600 32.98000 35.28200  1.000 119.81000 ?  891  GLU AAZA OE2 1 
ATOM   2433 N N   . GLN A 1 350 ? 24.16600 27.74100 36.97700  1.000 80.25000  ?  892  GLN AAZA N   1 
ATOM   2434 C CA  . GLN A 1 350 ? 24.22900 26.34500 36.56700  1.000 74.34000  ?  892  GLN AAZA CA  1 
ATOM   2435 C C   . GLN A 1 350 ? 24.56900 25.39200 37.69900  1.000 73.21000  ?  892  GLN AAZA C   1 
ATOM   2436 O O   . GLN A 1 350 ? 24.84200 24.21900 37.45800  1.000 70.73000  ?  892  GLN AAZA O   1 
ATOM   2437 C CB  . GLN A 1 350 ? 25.22600 26.21600 35.42400  1.000 75.76000  ?  892  GLN AAZA CB  1 
ATOM   2438 C CG  . GLN A 1 350 ? 24.80200 27.09200 34.27100  1.000 86.59000  ?  892  GLN AAZA CG  1 
ATOM   2439 C CD  . GLN A 1 350 ? 25.76700 27.08900 33.12400  1.000 90.13000  ?  892  GLN AAZA CD  1 
ATOM   2440 O OE1 . GLN A 1 350 ? 26.06500 28.14900 32.55700  1.000 88.89000  ?  892  GLN AAZA OE1 1 
ATOM   2441 N NE2 . GLN A 1 350 ? 26.28600 25.90800 32.78000  1.000 85.26000  ?  892  GLN AAZA NE2 1 
ATOM   2442 N N   . ILE A 1 351 ? 24.53900 25.84700 38.93000  1.000 80.28000  ?  893  ILE AAZA N   1 
ATOM   2443 C CA  . ILE A 1 351 ? 24.84000 24.93200 40.02400  1.000 82.99000  ?  893  ILE AAZA CA  1 
ATOM   2444 C C   . ILE A 1 351 ? 23.59800 24.09000 40.30200  1.000 84.34000  ?  893  ILE AAZA C   1 
ATOM   2445 O O   . ILE A 1 351 ? 22.48100 24.63400 40.30500  1.000 84.41000  ?  893  ILE AAZA O   1 
ATOM   2446 C CB  . ILE A 1 351 ? 25.29600 25.70400 41.25800  1.000 81.46000  ?  893  ILE AAZA CB  1 
ATOM   2447 C CG1 . ILE A 1 351 ? 26.55100 26.50200 40.91800  1.000 76.99000  ?  893  ILE AAZA CG1 1 
ATOM   2448 C CG2 . ILE A 1 351 ? 25.66100 24.76000 42.37700  1.000 83.57000  ?  893  ILE AAZA CG2 1 
ATOM   2449 C CD1 . ILE A 1 351 ? 27.69400 25.62800 40.47200  1.000 74.06000  ?  893  ILE AAZA CD1 1 
ATOM   2450 N N   . PRO A 1 352 ? 23.74000 22.77300 40.46100  1.000 84.87000  ?  894  PRO AAZA N   1 
ATOM   2451 C CA  . PRO A 1 352 ? 22.60000 21.94800 40.86800  1.000 80.76000  ?  894  PRO AAZA CA  1 
ATOM   2452 C C   . PRO A 1 352 ? 21.90300 22.57800 42.05700  1.000 86.84000  ?  894  PRO AAZA C   1 
ATOM   2453 O O   . PRO A 1 352 ? 22.54700 22.97700 43.03100  1.000 92.25000  ?  894  PRO AAZA O   1 
ATOM   2454 C CB  . PRO A 1 352 ? 23.25300 20.62000 41.24900  1.000 84.89000  ?  894  PRO AAZA CB  1 
ATOM   2455 C CG  . PRO A 1 352 ? 24.50700 20.56900 40.45300  1.000 85.00000  ?  894  PRO AAZA CG  1 
ATOM   2456 C CD  . PRO A 1 352 ? 24.97400 21.98100 40.29800  1.000 84.26000  ?  894  PRO AAZA CD  1 
ATOM   2457 N N   . SER A 1 353 ? 20.57700 22.67900 41.98300  1.000 89.38000  ?  895  SER AAZA N   1 
ATOM   2458 C CA  . SER A 1 353 ? 19.85300 23.33600 43.06800  1.000 90.10000  ?  895  SER AAZA CA  1 
ATOM   2459 C C   . SER A 1 353 ? 20.09300 22.66200 44.41700  1.000 85.99000  ?  895  SER AAZA C   1 
ATOM   2460 O O   . SER A 1 353 ? 20.09400 23.34400 45.44200  1.000 83.53000  ?  895  SER AAZA O   1 
ATOM   2461 C CB  . SER A 1 353 ? 18.36800 23.40600 42.73900  1.000 89.30000  ?  895  SER AAZA CB  1 
ATOM   2462 O OG  . SER A 1 353 ? 18.21300 23.67600 41.35400  1.000 105.81000 ?  895  SER AAZA OG  1 
ATOM   2463 N N   . ARG A 1 354 ? 20.34400 21.34900 44.44600  1.000 87.36000  ?  896  ARG AAZA N   1 
ATOM   2464 C CA  . ARG A 1 354 ? 20.66300 20.73000 45.72800  1.000 92.74000  ?  896  ARG AAZA CA  1 
ATOM   2465 C C   . ARG A 1 354 ? 21.94000 21.32100 46.30800  1.000 94.29000  ?  896  ARG AAZA C   1 
ATOM   2466 O O   . ARG A 1 354 ? 22.05400 21.47600 47.53200  1.000 96.16000  ?  896  ARG AAZA O   1 
ATOM   2467 C CB  . ARG A 1 354 ? 20.80700 19.20400 45.61900  1.000 96.60000  ?  896  ARG AAZA CB  1 
ATOM   2468 C CG  . ARG A 1 354 ? 21.28500 18.55900 46.95600  1.000 102.78000 ?  896  ARG AAZA CG  1 
ATOM   2469 C CD  . ARG A 1 354 ? 21.99000 17.21100 46.81100  1.000 110.07000 ?  896  ARG AAZA CD  1 
ATOM   2470 N NE  . ARG A 1 354 ? 23.08900 17.28900 45.85400  1.000 117.79000 ?  896  ARG AAZA NE  1 
ATOM   2471 C CZ  . ARG A 1 354 ? 23.25300 16.47600 44.81700  1.000 122.40000 ?  896  ARG AAZA CZ  1 
ATOM   2472 N NH1 . ARG A 1 354 ? 22.47700 15.41200 44.63900  1.000 119.56000 ?  896  ARG AAZA NH1 1 
ATOM   2473 N NH2 . ARG A 1 354 ? 24.22300 16.73300 43.93800  1.000 111.54000 ?  896  ARG AAZA NH2 1 
ATOM   2474 N N   . GLN A 1 355 ? 22.89800 21.67700 45.44700  1.000 90.95000  ?  897  GLN AAZA N   1 
ATOM   2475 C CA  . GLN A 1 355 ? 24.15100 22.26000 45.92200  1.000 90.60000  ?  897  GLN AAZA CA  1 
ATOM   2476 C C   . GLN A 1 355 ? 23.95300 23.68800 46.41900  1.000 94.49000  ?  897  GLN AAZA C   1 
ATOM   2477 O O   . GLN A 1 355 ? 24.48300 24.06000 47.47700  1.000 91.35000  ?  897  GLN AAZA O   1 
ATOM   2478 C CB  . GLN A 1 355 ? 25.19000 22.22600 44.81300  1.000 85.42000  ?  897  GLN AAZA CB  1 
ATOM   2479 C CG  . GLN A 1 355 ? 25.30700 20.89200 44.13800  1.000 89.96000  ?  897  GLN AAZA CG  1 
ATOM   2480 C CD  . GLN A 1 355 ? 26.74500 20.51200 43.88500  1.000 91.81000  ?  897  GLN AAZA CD  1 
ATOM   2481 O OE1 . GLN A 1 355 ? 27.25800 20.73000 42.79000  1.000 92.76000  ?  897  GLN AAZA OE1 1 
ATOM   2482 N NE2 . GLN A 1 355 ? 27.41000 19.94500 44.89400  1.000 89.33000  ?  897  GLN AAZA NE2 1 
ATOM   2483 N N   . LYS A 1 356 ? 23.20000 24.50400 45.66400  1.000 94.82000  ?  898  LYS AAZA N   1 
ATOM   2484 C CA  . LYS A 1 356 ? 22.89300 25.86200 46.11000  1.000 92.11000  ?  898  LYS AAZA CA  1 
ATOM   2485 C C   . LYS A 1 356 ? 22.30700 25.86700 47.51900  1.000 93.05000  ?  898  LYS AAZA C   1 
ATOM   2486 O O   . LYS A 1 356 ? 22.62500 26.74800 48.32300  1.000 96.95000  ?  898  LYS AAZA O   1 
ATOM   2487 C CB  . LYS A 1 356 ? 21.94200 26.54700 45.12500  1.000 83.69000  ?  898  LYS AAZA CB  1 
ATOM   2488 C CG  . LYS A 1 356 ? 22.63500 27.03300 43.89500  1.000 79.11000  ?  898  LYS AAZA CG  1 
ATOM   2489 C CD  . LYS A 1 356 ? 21.70100 27.19100 42.73100  1.000 79.85000  ?  898  LYS AAZA CD  1 
ATOM   2490 C CE  . LYS A 1 356 ? 21.37100 28.63300 42.46700  1.000 82.54000  ?  898  LYS AAZA CE  1 
ATOM   2491 N NZ  . LYS A 1 356 ? 20.91800 28.79500 41.04500  1.000 90.65000  ?  898  LYS AAZA NZ  1 
ATOM   2492 N N   . LYS A 1 357 ? 21.47000 24.87900 47.85100  1.000 93.46000  ?  899  LYS AAZA N   1 
ATOM   2493 C CA  . LYS A 1 357 ? 20.97100 24.78800 49.21700  1.000 93.06000  ?  899  LYS AAZA CA  1 
ATOM   2494 C C   . LYS A 1 357 ? 22.09400 24.49900 50.20800  1.000 94.78000  ?  899  LYS AAZA C   1 
ATOM   2495 O O   . LYS A 1 357 ? 22.12600 25.09000 51.29500  1.000 93.38000  ?  899  LYS AAZA O   1 
ATOM   2496 C CB  . LYS A 1 357 ? 19.87000 23.73700 49.31800  1.000 95.03000  ?  899  LYS AAZA CB  1 
ATOM   2497 C CG  . LYS A 1 357 ? 19.30100 23.63400 50.73500  1.000 106.35000 ?  899  LYS AAZA CG  1 
ATOM   2498 C CD  . LYS A 1 357 ? 18.96800 25.02100 51.31600  1.000 106.04000 ?  899  LYS AAZA CD  1 
ATOM   2499 C CE  . LYS A 1 357 ? 18.93900 24.99600 52.85000  1.000 110.02000 ?  899  LYS AAZA CE  1 
ATOM   2500 N NZ  . LYS A 1 357 ? 18.93000 26.35800 53.49000  1.000 104.76000 ?  899  LYS AAZA NZ  1 
ATOM   2501 N N   . ILE A 1 358 ? 23.02700 23.60500 49.85400  1.000 95.58000  ?  900  ILE AAZA N   1 
ATOM   2502 C CA  . ILE A 1 358 ? 24.13500 23.27300 50.75500  1.000 91.23000  ?  900  ILE AAZA CA  1 
ATOM   2503 C C   . ILE A 1 358 ? 24.92900 24.52400 51.11200  1.000 91.37000  ?  900  ILE AAZA C   1 
ATOM   2504 O O   . ILE A 1 358 ? 25.34400 24.70700 52.26500  1.000 90.70000  ?  900  ILE AAZA O   1 
ATOM   2505 C CB  . ILE A 1 358 ? 25.05100 22.20400 50.12600  1.000 87.75000  ?  900  ILE AAZA CB  1 
ATOM   2506 C CG1 . ILE A 1 358 ? 24.25200 21.00400 49.61500  1.000 93.43000  ?  900  ILE AAZA CG1 1 
ATOM   2507 C CG2 . ILE A 1 358 ? 26.11100 21.76300 51.10600  1.000 87.45000  ?  900  ILE AAZA CG2 1 
ATOM   2508 C CD1 . ILE A 1 358 ? 23.46300 20.27100 50.64800  1.000 100.95000 ?  900  ILE AAZA CD1 1 
ATOM   2509 N N   . LEU A 1 359 ? 25.16300 25.39900 50.12500  1.000 87.63000  ?  901  LEU AAZA N   1 
ATOM   2510 C CA  . LEU A 1 359 ? 25.93600 26.61600 50.35300  1.000 86.15000  ?  901  LEU AAZA CA  1 
ATOM   2511 C C   . LEU A 1 359 ? 25.11300 27.66600 51.08300  1.000 86.53000  ?  901  LEU AAZA C   1 
ATOM   2512 O O   . LEU A 1 359 ? 25.61900 28.33400 51.99200  1.000 86.20000  ?  901  LEU AAZA O   1 
ATOM   2513 C CB  . LEU A 1 359 ? 26.43600 27.17500 49.02200  1.000 85.89000  ?  901  LEU AAZA CB  1 
ATOM   2514 C CG  . LEU A 1 359 ? 27.25800 28.46800 49.07700  1.000 79.87000  ?  901  LEU AAZA CG  1 
ATOM   2515 C CD1 . LEU A 1 359 ? 28.51700 28.25400 49.88900  1.000 72.19000  ?  901  LEU AAZA CD1 1 
ATOM   2516 C CD2 . LEU A 1 359 ? 27.60500 28.96000 47.68600  1.000 74.01000  ?  901  LEU AAZA CD2 1 
ATOM   2517 N N   . GLU A 1 360 ? 23.85700 27.84000 50.65800  1.000 89.38000  ?  902  GLU AAZA N   1 
ATOM   2518 C CA  . GLU A 1 360 ? 22.88800 28.69300 51.34400  1.000 86.77000  ?  902  GLU AAZA CA  1 
ATOM   2519 C C   . GLU A 1 360 ? 22.80700 28.37800 52.83800  1.000 92.24000  ?  902  GLU AAZA C   1 
ATOM   2520 O O   . GLU A 1 360 ? 22.79800 29.28300 53.68300  1.000 86.48000  ?  902  GLU AAZA O   1 
ATOM   2521 C CB  . GLU A 1 360 ? 21.55200 28.50000 50.63300  1.000 85.99000  ?  902  GLU AAZA CB  1 
ATOM   2522 C CG  . GLU A 1 360 ? 20.26600 28.88200 51.30500  1.000 101.39000 ?  902  GLU AAZA CG  1 
ATOM   2523 C CD  . GLU A 1 360 ? 19.93100 30.34200 51.10100  1.000 109.73000 ?  902  GLU AAZA CD  1 
ATOM   2524 O OE1 . GLU A 1 360 ? 20.88300 31.09800 50.82400  1.000 107.56000 ?  902  GLU AAZA OE1 1 
ATOM   2525 O OE2 . GLU A 1 360 ? 18.72700 30.71300 51.13100  1.000 114.21000 ?  902  GLU AAZA OE2 1 
ATOM   2526 N N   . GLU A 1 361 ? 22.75700 27.09400 53.18000  1.000 92.60000  ?  903  GLU AAZA N   1 
ATOM   2527 C CA  . GLU A 1 361 ? 22.85100 26.68400 54.57100  1.000 89.90000  ?  903  GLU AAZA CA  1 
ATOM   2528 C C   . GLU A 1 361 ? 24.07300 27.28400 55.25100  1.000 89.99000  ?  903  GLU AAZA C   1 
ATOM   2529 O O   . GLU A 1 361 ? 23.95900 27.93800 56.29000  1.000 91.31000  ?  903  GLU AAZA O   1 
ATOM   2530 C CB  . GLU A 1 361 ? 22.88800 25.16300 54.63100  1.000 96.78000  ?  903  GLU AAZA CB  1 
ATOM   2531 C CG  . GLU A 1 361 ? 21.60000 24.54500 55.10900  1.000 103.77000 ?  903  GLU AAZA CG  1 
ATOM   2532 C CD  . GLU A 1 361 ? 21.49500 24.60000 56.61500  1.000 114.54000 ?  903  GLU AAZA CD  1 
ATOM   2533 O OE1 . GLU A 1 361 ? 22.51700 24.96800 57.25700  1.000 112.78000 ?  903  GLU AAZA OE1 1 
ATOM   2534 O OE2 . GLU A 1 361 ? 20.40800 24.27600 57.15200  1.000 118.82000 ?  903  GLU AAZA OE2 1 
ATOM   2535 N N   . ALA A 1 362 ? 25.25700 27.07200 54.67300  1.000 91.22000  ?  904  ALA AAZA N   1 
ATOM   2536 C CA  . ALA A 1 362 ? 26.49500 27.48700 55.32900  1.000 85.58000  ?  904  ALA AAZA CA  1 
ATOM   2537 C C   . ALA A 1 362 ? 26.57100 29.00100 55.46200  1.000 79.83000  ?  904  ALA AAZA C   1 
ATOM   2538 O O   . ALA A 1 362 ? 26.92700 29.52500 56.51800  1.000 80.41000  ?  904  ALA AAZA O   1 
ATOM   2539 C CB  . ALA A 1 362 ? 27.70300 26.95100 54.55600  1.000 82.37000  ?  904  ALA AAZA CB  1 
ATOM   2540 N N   . HIS A 1 363 ? 26.24100 29.72100 54.39800  1.000 82.69000  ?  905  HIS AAZA N   1 
ATOM   2541 C CA  . HIS A 1 363 ? 26.27600 31.17600 54.44500  1.000 83.10000  ?  905  HIS AAZA CA  1 
ATOM   2542 C C   . HIS A 1 363 ? 25.32000 31.73900 55.49900  1.000 86.17000  ?  905  HIS AAZA C   1 
ATOM   2543 O O   . HIS A 1 363 ? 25.59100 32.79800 56.07700  1.000 84.64000  ?  905  HIS AAZA O   1 
ATOM   2544 C CB  . HIS A 1 363 ? 25.93200 31.72500 53.06700  1.000 80.78000  ?  905  HIS AAZA CB  1 
ATOM   2545 C CG  . HIS A 1 363 ? 25.75600 33.20400 53.03700  1.000 80.11000  ?  905  HIS AAZA CG  1 
ATOM   2546 N ND1 . HIS A 1 363 ? 26.81800 34.08000 52.99700  1.000 78.71000  ?  905  HIS AAZA ND1 1 
ATOM   2547 C CD2 . HIS A 1 363 ? 24.63900 33.96300 53.10400  1.000 79.84000  ?  905  HIS AAZA CD2 1 
ATOM   2548 C CE1 . HIS A 1 363 ? 26.35900 35.31700 52.99500  1.000 82.53000  ?  905  HIS AAZA CE1 1 
ATOM   2549 N NE2 . HIS A 1 363 ? 25.04000 35.27400 53.07100  1.000 81.62000  ?  905  HIS AAZA NE2 1 
ATOM   2550 N N   . GLU A 1 364 ? 24.20000 31.05500 55.76200  1.000 86.91000  ?  906  GLU AAZA N   1 
ATOM   2551 C CA  . GLU A 1 364 ? 23.23700 31.56100 56.74000  1.000 87.17000  ?  906  GLU AAZA CA  1 
ATOM   2552 C C   . GLU A 1 364 ? 23.75700 31.42500 58.16900  1.000 82.39000  ?  906  GLU AAZA C   1 
ATOM   2553 O O   . GLU A 1 364 ? 23.36900 32.21000 59.04200  1.000 79.44000  ?  906  GLU AAZA O   1 
ATOM   2554 C CB  . GLU A 1 364 ? 21.89800 30.83600 56.58500  1.000 95.95000  ?  906  GLU AAZA CB  1 
ATOM   2555 C CG  . GLU A 1 364 ? 21.06900 31.29000 55.37000  1.000 105.02000 ?  906  GLU AAZA CG  1 
ATOM   2556 C CD  . GLU A 1 364 ? 19.63100 30.75900 55.38900  1.000 112.47000 ?  906  GLU AAZA CD  1 
ATOM   2557 O OE1 . GLU A 1 364 ? 18.77400 31.40000 56.04300  1.000 121.35000 ?  906  GLU AAZA OE1 1 
ATOM   2558 O OE2 . GLU A 1 364 ? 19.36200 29.69700 54.76400  1.000 98.36000  ?  906  GLU AAZA OE2 1 
ATOM   2559 N N   . LEU A 1 365 ? 24.61400 30.43200 58.43000  1.000 82.47000  ?  907  LEU AAZA N   1 
ATOM   2560 C CA  . LEU A 1 365 ? 25.37600 30.40200 59.67600  1.000 79.06000  ?  907  LEU AAZA CA  1 
ATOM   2561 C C   . LEU A 1 365 ? 25.92000 31.77500 60.00600  1.000 82.11000  ?  907  LEU AAZA C   1 
ATOM   2562 O O   . LEU A 1 365 ? 25.68700 32.30700 61.09700  1.000 80.05000  ?  907  LEU AAZA O   1 
ATOM   2563 C CB  . LEU A 1 365 ? 26.54700 29.43700 59.57300  1.000 73.76000  ?  907  LEU AAZA CB  1 
ATOM   2564 C CG  . LEU A 1 365 ? 26.31600 27.97500 59.32200  1.000 74.66000  ?  907  LEU AAZA CG  1 
ATOM   2565 C CD1 . LEU A 1 365 ? 27.66900 27.35900 59.27900  1.000 72.46000  ?  907  LEU AAZA CD1 1 
ATOM   2566 C CD2 . LEU A 1 365 ? 25.52600 27.43400 60.48300  1.000 81.46000  ?  907  LEU AAZA CD2 1 
ATOM   2567 N N   . SER A 1 366 ? 26.65300 32.36000 59.05600  1.000 81.13000  ?  908  SER AAZA N   1 
ATOM   2568 C CA  . SER A 1 366 ? 27.32800 33.62300 59.30400  1.000 77.91000  ?  908  SER AAZA CA  1 
ATOM   2569 C C   . SER A 1 366 ? 26.32900 34.74700 59.56700  1.000 78.95000  ?  908  SER AAZA C   1 
ATOM   2570 O O   . SER A 1 366 ? 26.58100 35.62600 60.39600  1.000 77.20000  ?  908  SER AAZA O   1 
ATOM   2571 C CB  . SER A 1 366 ? 28.24000 33.94800 58.12100  1.000 78.69000  ?  908  SER AAZA CB  1 
ATOM   2572 O OG  . SER A 1 366 ? 27.48800 34.44700 57.02500  1.000 85.47000  ?  908  SER AAZA OG  1 
ATOM   2573 N N   . GLU A 1 367 ? 25.18300 34.72000 58.89400  1.000 81.47000  ?  909  GLU AAZA N   1 
ATOM   2574 C CA  . GLU A 1 367 ? 24.22900 35.81800 58.95800  1.000 81.39000  ?  909  GLU AAZA CA  1 
ATOM   2575 C C   . GLU A 1 367 ? 23.79300 36.07500 60.38800  1.000 84.80000  ?  909  GLU AAZA C   1 
ATOM   2576 O O   . GLU A 1 367 ? 23.80300 35.17100 61.23000  1.000 91.69000  ?  909  GLU AAZA O   1 
ATOM   2577 C CB  . GLU A 1 367 ? 23.01900 35.49500 58.09900  1.000 87.63000  ?  909  GLU AAZA CB  1 
ATOM   2578 C CG  . GLU A 1 367 ? 23.25700 35.73200 56.60000  1.000 100.28000 ?  909  GLU AAZA CG  1 
ATOM   2579 C CD  . GLU A 1 367 ? 22.09500 35.23700 55.73100  1.000 110.65000 ?  909  GLU AAZA CD  1 
ATOM   2580 O OE1 . GLU A 1 367 ? 21.02300 34.89500 56.29600  1.000 111.29000 ?  909  GLU AAZA OE1 1 
ATOM   2581 O OE2 . GLU A 1 367 ? 22.25400 35.20900 54.48500  1.000 110.73000 ?  909  GLU AAZA OE2 1 
ATOM   2582 N N   . ASP A 1 368 ? 23.41500 37.32900 60.66400  1.000 84.60000  ?  910  ASP AAZA N   1 
ATOM   2583 C CA  . ASP A 1 368 ? 22.92200 37.74100 61.98000  1.000 84.35000  ?  910  ASP AAZA CA  1 
ATOM   2584 C C   . ASP A 1 368 ? 23.95200 37.56100 63.08500  1.000 78.52000  ?  910  ASP AAZA C   1 
ATOM   2585 O O   . ASP A 1 368 ? 23.69000 36.85900 64.05800  1.000 84.33000  ?  910  ASP AAZA O   1 
ATOM   2586 C CB  . ASP A 1 368 ? 21.65800 36.96700 62.37500  1.000 93.73000  ?  910  ASP AAZA CB  1 
ATOM   2587 C CG  . ASP A 1 368 ? 20.40200 37.48800 61.69900  1.000 107.43000 ?  910  ASP AAZA CG  1 
ATOM   2588 O OD1 . ASP A 1 368 ? 20.34200 37.52600 60.44700  1.000 115.69000 ?  910  ASP AAZA OD1 1 
ATOM   2589 O OD2 . ASP A 1 368 ? 19.45800 37.84300 62.44000  1.000 112.83000 ?  910  ASP AAZA OD2 1 
ATOM   2590 N N   . HIS A 1 369 ? 25.11200 38.18200 62.95000  1.000 75.69000  ?  911  HIS AAZA N   1 
ATOM   2591 C CA  . HIS A 1 369 ? 26.14900 38.13000 63.97200  1.000 69.92000  ?  911  HIS AAZA CA  1 
ATOM   2592 C C   . HIS A 1 369 ? 26.42900 36.69100 64.40500  1.000 66.83000  ?  911  HIS AAZA C   1 
ATOM   2593 O O   . HIS A 1 369 ? 26.63800 36.39100 65.57400  1.000 70.43000  ?  911  HIS AAZA O   1 
ATOM   2594 C CB  . HIS A 1 369 ? 25.78100 39.04000 65.14100  1.000 70.47000  ?  911  HIS AAZA CB  1 
ATOM   2595 C CG  . HIS A 1 369 ? 25.77500 40.49700 64.78200  1.000 73.25000  ?  911  HIS AAZA CG  1 
ATOM   2596 N ND1 . HIS A 1 369 ? 26.83000 41.33900 65.06600  1.000 75.82000  ?  911  HIS AAZA ND1 1 
ATOM   2597 C CD2 . HIS A 1 369 ? 24.83800 41.26600 64.17700  1.000 73.72000  ?  911  HIS AAZA CD2 1 
ATOM   2598 C CE1 . HIS A 1 369 ? 26.55100 42.55700 64.63200  1.000 73.27000  ?  911  HIS AAZA CE1 1 
ATOM   2599 N NE2 . HIS A 1 369 ? 25.34500 42.54100 64.09500  1.000 70.33000  ?  911  HIS AAZA NE2 1 
ATOM   2600 N N   . TYR A 1 370 ? 26.43800 35.79300 63.43100  1.000 69.19000  ?  912  TYR AAZA N   1 
ATOM   2601 C CA  . TYR A 1 370 ? 26.79000 34.38500 63.62300  1.000 76.90000  ?  912  TYR AAZA CA  1 
ATOM   2602 C C   . TYR A 1 370 ? 25.81000 33.65200 64.52700  1.000 79.17000  ?  912  TYR AAZA C   1 
ATOM   2603 O O   . TYR A 1 370 ? 26.18900 32.68200 65.19500  1.000 74.13000  ?  912  TYR AAZA O   1 
ATOM   2604 C CB  . TYR A 1 370 ? 28.21400 34.21100 64.16400  1.000 73.51000  ?  912  TYR AAZA CB  1 
ATOM   2605 C CG  . TYR A 1 370 ? 29.31400 34.39600 63.14800  1.000 71.40000  ?  912  TYR AAZA CG  1 
ATOM   2606 C CD1 . TYR A 1 370 ? 29.44300 33.54200 62.08000  1.000 73.94000  ?  912  TYR AAZA CD1 1 
ATOM   2607 C CD2 . TYR A 1 370 ? 30.21800 35.42600 63.26400  1.000 71.97000  ?  912  TYR AAZA CD2 1 
ATOM   2608 C CE1 . TYR A 1 370 ? 30.44200 33.71000 61.16400  1.000 72.29000  ?  912  TYR AAZA CE1 1 
ATOM   2609 C CE2 . TYR A 1 370 ? 31.20800 35.59600 62.36200  1.000 67.59000  ?  912  TYR AAZA CE2 1 
ATOM   2610 C CZ  . TYR A 1 370 ? 31.31600 34.73700 61.32100  1.000 68.84000  ?  912  TYR AAZA CZ  1 
ATOM   2611 O OH  . TYR A 1 370 ? 32.31300 34.92000 60.41900  1.000 76.66000  ?  912  TYR AAZA OH  1 
ATOM   2612 N N   . LYS A 1 371 ? 24.53900 34.07000 64.51700  1.000 83.06000  ?  913  LYS AAZA N   1 
ATOM   2613 C CA  . LYS A 1 371 ? 23.56500 33.47100 65.42400  1.000 82.22000  ?  913  LYS AAZA CA  1 
ATOM   2614 C C   . LYS A 1 371 ? 23.38800 31.98500 65.14200  1.000 81.45000  ?  913  LYS AAZA C   1 
ATOM   2615 O O   . LYS A 1 371 ? 23.55700 31.14900 66.04200  1.000 79.44000  ?  913  LYS AAZA O   1 
ATOM   2616 C CB  . LYS A 1 371 ? 22.22700 34.20600 65.34100  1.000 85.54000  ?  913  LYS AAZA CB  1 
ATOM   2617 C CG  . LYS A 1 371 ? 21.19600 33.65600 66.31300  1.000 92.79000  ?  913  LYS AAZA CG  1 
ATOM   2618 C CD  . LYS A 1 371 ? 19.83000 34.30700 66.14900  1.000 100.07000 ?  913  LYS AAZA CD  1 
ATOM   2619 C CE  . LYS A 1 371 ? 19.87600 35.74800 66.63700  1.000 109.50000 ?  913  LYS AAZA CE  1 
ATOM   2620 N NZ  . LYS A 1 371 ? 18.52200 36.34600 66.79300  1.000 115.97000 ?  913  LYS AAZA NZ  1 
ATOM   2621 N N   . LYS A 1 372 ? 23.07700 31.63300 63.88900  1.000 76.76000  ?  914  LYS AAZA N   1 
ATOM   2622 C CA  . LYS A 1 372 ? 22.86100 30.23000 63.55900  1.000 72.46000  ?  914  LYS AAZA CA  1 
ATOM   2623 C C   . LYS A 1 372 ? 24.12700 29.41000 63.78400  1.000 75.97000  ?  914  LYS AAZA C   1 
ATOM   2624 O O   . LYS A 1 372 ? 24.05900 28.27600 64.27800  1.000 74.62000  ?  914  LYS AAZA O   1 
ATOM   2625 C CB  . LYS A 1 372 ? 22.38500 30.12200 62.12200  1.000 71.28000  ?  914  LYS AAZA CB  1 
ATOM   2626 C CG  . LYS A 1 372 ? 21.02800 30.71200 61.90800  1.000 72.60000  ?  914  LYS AAZA CG  1 
ATOM   2627 C CD  . LYS A 1 372 ? 20.37000 30.13000 60.68100  1.000 84.61000  ?  914  LYS AAZA CD  1 
ATOM   2628 C CE  . LYS A 1 372 ? 18.89400 30.50700 60.56300  1.000 91.67000  ?  914  LYS AAZA CE  1 
ATOM   2629 N NZ  . LYS A 1 372 ? 18.34000 30.06400 59.24100  1.000 97.73000  ?  914  LYS AAZA NZ  1 
ATOM   2630 N N   . TYR A 1 373 ? 25.29300 29.98100 63.44400  1.000 78.74000  ?  915  TYR AAZA N   1 
ATOM   2631 C CA  . TYR A 1 373 ? 26.57800 29.33100 63.70800  1.000 75.06000  ?  915  TYR AAZA CA  1 
ATOM   2632 C C   . TYR A 1 373 ? 26.76600 29.05100 65.19000  1.000 72.42000  ?  915  TYR AAZA C   1 
ATOM   2633 O O   . TYR A 1 373 ? 27.23000 27.97300 65.57700  1.000 70.73000  ?  915  TYR AAZA O   1 
ATOM   2634 C CB  . TYR A 1 373 ? 27.74000 30.20600 63.25400  1.000 74.28000  ?  915  TYR AAZA CB  1 
ATOM   2635 C CG  . TYR A 1 373 ? 29.04100 29.73700 63.88100  1.000 69.53000  ?  915  TYR AAZA CG  1 
ATOM   2636 C CD1 . TYR A 1 373 ? 29.65300 28.58700 63.45400  1.000 68.22000  ?  915  TYR AAZA CD1 1 
ATOM   2637 C CD2 . TYR A 1 373 ? 29.58300 30.37700 64.97400  1.000 69.69000  ?  915  TYR AAZA CD2 1 
ATOM   2638 C CE1 . TYR A 1 373 ? 30.82200 28.13700 64.03900  1.000 74.48000  ?  915  TYR AAZA CE1 1 
ATOM   2639 C CE2 . TYR A 1 373 ? 30.73300 29.91600 65.58000  1.000 67.58000  ?  915  TYR AAZA CE2 1 
ATOM   2640 C CZ  . TYR A 1 373 ? 31.35100 28.80000 65.10900  1.000 69.64000  ?  915  TYR AAZA CZ  1 
ATOM   2641 O OH  . TYR A 1 373 ? 32.50900 28.35100 65.70300  1.000 69.33000  ?  915  TYR AAZA OH  1 
ATOM   2642 N N   . LEU A 1 374 ? 26.50800 30.06100 66.02800  1.000 70.31000  ?  916  LEU AAZA N   1 
ATOM   2643 C CA  . LEU A 1 374 ? 26.70600 29.90700 67.46700  1.000 70.31000  ?  916  LEU AAZA CA  1 
ATOM   2644 C C   . LEU A 1 374 ? 25.80400 28.81600 68.01100  1.000 72.87000  ?  916  LEU AAZA C   1 
ATOM   2645 O O   . LEU A 1 374 ? 26.25300 27.93800 68.75900  1.000 72.70000  ?  916  LEU AAZA O   1 
ATOM   2646 C CB  . LEU A 1 374 ? 26.45900 31.23800 68.17900  1.000 63.10000  ?  916  LEU AAZA CB  1 
ATOM   2647 C CG  . LEU A 1 374 ? 27.59100 32.26400 68.14600  1.000 57.70000  ?  916  LEU AAZA CG  1 
ATOM   2648 C CD1 . LEU A 1 374 ? 27.16500 33.60500 68.70200  1.000 59.09000  ?  916  LEU AAZA CD1 1 
ATOM   2649 C CD2 . LEU A 1 374 ? 28.80400 31.74800 68.87600  1.000 56.48000  ?  916  LEU AAZA CD2 1 
ATOM   2650 N N   . ALA A 1 375 ? 24.53100 28.84000 67.61000  1.000 73.80000  ?  917  ALA AAZA N   1 
ATOM   2651 C CA  . ALA A 1 375 ? 23.60500 27.76500 67.94500  1.000 76.78000  ?  917  ALA AAZA CA  1 
ATOM   2652 C C   . ALA A 1 375 ? 24.19700 26.40100 67.61100  1.000 82.16000  ?  917  ALA AAZA C   1 
ATOM   2653 O O   . ALA A 1 375 ? 24.45400 25.57800 68.50100  1.000 81.36000  ?  917  ALA AAZA O   1 
ATOM   2654 C CB  . ALA A 1 375 ? 22.28900 27.96900 67.20000  1.000 71.75000  ?  917  ALA AAZA CB  1 
ATOM   2655 N N   . LYS A 1 376 ? 24.44400 26.16400 66.32000  1.000 80.14000  ?  918  LYS AAZA N   1 
ATOM   2656 C CA  . LYS A 1 376 ? 24.87300 24.84500 65.87600  1.000 81.34000  ?  918  LYS AAZA CA  1 
ATOM   2657 C C   . LYS A 1 376 ? 26.09800 24.34000 66.65300  1.000 86.38000  ?  918  LYS AAZA C   1 
ATOM   2658 O O   . LYS A 1 376 ? 26.14200 23.16900 67.03700  1.000 91.47000  ?  918  LYS AAZA O   1 
ATOM   2659 C CB  . LYS A 1 376 ? 25.12900 24.87300 64.36800  1.000 76.04000  ?  918  LYS AAZA CB  1 
ATOM   2660 C CG  . LYS A 1 376 ? 25.95600 23.71100 63.87900  1.000 78.10000  ?  918  LYS AAZA CG  1 
ATOM   2661 C CD  . LYS A 1 376 ? 25.51300 23.24900 62.52200  1.000 86.07000  ?  918  LYS AAZA CD  1 
ATOM   2662 C CE  . LYS A 1 376 ? 24.30700 22.34300 62.65500  1.000 96.37000  ?  918  LYS AAZA CE  1 
ATOM   2663 N NZ  . LYS A 1 376 ? 24.14800 21.46200 61.47200  1.000 99.22000  ?  918  LYS AAZA NZ  1 
ATOM   2664 N N   . LEU A 1 377 ? 27.08700 25.20300 66.93300  1.000 81.39000  ?  919  LEU AAZA N   1 
ATOM   2665 C CA  . LEU A 1 377 ? 28.28200 24.72300 67.62600  1.000 78.89000  ?  919  LEU AAZA CA  1 
ATOM   2666 C C   . LEU A 1 377 ? 27.94800 24.24500 69.03400  1.000 86.15000  ?  919  LEU AAZA C   1 
ATOM   2667 O O   . LEU A 1 377 ? 28.56400 23.29500 69.53800  1.000 85.52000  ?  919  LEU AAZA O   1 
ATOM   2668 C CB  . LEU A 1 377 ? 29.36100 25.80600 67.68500  1.000 78.21000  ?  919  LEU AAZA CB  1 
ATOM   2669 C CG  . LEU A 1 377 ? 30.55400 25.57500 68.65300  1.000 77.93000  ?  919  LEU AAZA CG  1 
ATOM   2670 C CD1 . LEU A 1 377 ? 31.36500 24.33000 68.36300  1.000 75.81000  ?  919  LEU AAZA CD1 1 
ATOM   2671 C CD2 . LEU A 1 377 ? 31.48600 26.75900 68.72600  1.000 80.49000  ?  919  LEU AAZA CD2 1 
ATOM   2672 N N   . ARG A 1 378 ? 26.98200 24.89200 69.69600  1.000 89.40000  ?  920  ARG AAZA N   1 
ATOM   2673 C CA  . ARG A 1 378 ? 26.67800 24.47900 71.06500  1.000 95.78000  ?  920  ARG AAZA CA  1 
ATOM   2674 C C   . ARG A 1 378 ? 25.87100 23.19300 71.08900  1.000 94.02000  ?  920  ARG AAZA C   1 
ATOM   2675 O O   . ARG A 1 378 ? 25.81300 22.52200 72.12700  1.000 98.07000  ?  920  ARG AAZA O   1 
ATOM   2676 C CB  . ARG A 1 378 ? 25.93700 25.58100 71.83400  1.000 100.37000 ?  920  ARG AAZA CB  1 
ATOM   2677 C CG  . ARG A 1 378 ? 26.07900 25.44300 73.36000  1.000 110.80000 ?  920  ARG AAZA CG  1 
ATOM   2678 C CD  . ARG A 1 378 ? 25.37800 26.55700 74.13700  1.000 121.67000 ?  920  ARG AAZA CD  1 
ATOM   2679 N NE  . ARG A 1 378 ? 23.93000 26.36600 74.15800  1.000 137.66000 ?  920  ARG AAZA NE  1 
ATOM   2680 C CZ  . ARG A 1 378 ? 23.28700 25.52200 74.95900  1.000 139.64000 ?  920  ARG AAZA CZ  1 
ATOM   2681 N NH1 . ARG A 1 378 ? 23.93600 24.77200 75.83900  1.000 132.70000 ?  920  ARG AAZA NH1 1 
ATOM   2682 N NH2 . ARG A 1 378 ? 21.96100 25.42400 74.87300  1.000 141.03000 ?  920  ARG AAZA NH2 1 
ATOM   2683 N N   . SER A 1 379 ? 25.38800 22.78700 69.91600  1.000 90.40000  ?  921  SER AAZA N   1 
ATOM   2684 C CA  . SER A 1 379 ? 24.62600 21.52100 69.80700  1.000 89.77000  ?  921  SER AAZA CA  1 
ATOM   2685 C C   . SER A 1 379 ? 25.44200 20.32900 69.31100  1.000 91.67000  ?  921  SER AAZA C   1 
ATOM   2686 O O   . SER A 1 379 ? 25.28100 19.23700 69.87500  1.000 101.77000 ?  921  SER AAZA O   1 
ATOM   2687 C CB  . SER A 1 379 ? 23.52500 21.67000 68.80500  1.000 86.27000  ?  921  SER AAZA CB  1 
ATOM   2688 O OG  . SER A 1 379 ? 24.05200 21.85400 67.50100  1.000 85.94000  ?  921  SER AAZA OG  1 
ATOM   2689 N N   . ILE A 1 380 ? 26.28400 20.54000 68.30200  1.000 89.37000  ?  922  ILE AAZA N   1 
ATOM   2690 C CA  . ILE A 1 380 ? 27.06900 19.43100 67.68100  1.000 91.49000  ?  922  ILE AAZA CA  1 
ATOM   2691 C C   . ILE A 1 380 ? 27.94900 18.81500 68.77000  1.000 96.15000  ?  922  ILE AAZA C   1 
ATOM   2692 O O   . ILE A 1 380 ? 28.20200 19.49100 69.78300  1.000 95.12000  ?  922  ILE AAZA O   1 
ATOM   2693 C CB  . ILE A 1 380 ? 27.91100 19.97700 66.51200  1.000 92.47000  ?  922  ILE AAZA CB  1 
ATOM   2694 C CG1 . ILE A 1 380 ? 28.81800 21.13000 66.94600  1.000 91.07000  ?  922  ILE AAZA CG1 1 
ATOM   2695 C CG2 . ILE A 1 380 ? 27.01500 20.37700 65.35100  1.000 92.62000  ?  922  ILE AAZA CG2 1 
ATOM   2696 C CD1 . ILE A 1 380 ? 30.11400 20.69100 67.58400  1.000 90.70000  ?  922  ILE AAZA CD1 1 
ATOM   2697 N N   . ASN A 1 381 ? 28.42300 17.58600 68.54100  1.000 102.50000 ?  923  ASN AAZA N   1 
ATOM   2698 C CA  . ASN A 1 381 ? 29.28200 16.90500 69.49500  1.000 99.37000  ?  923  ASN AAZA CA  1 
ATOM   2699 C C   . ASN A 1 381 ? 30.66700 16.63600 68.90800  1.000 100.04000 ?  923  ASN AAZA C   1 
ATOM   2700 O O   . ASN A 1 381 ? 30.78600 16.16100 67.76800  1.000 100.10000 ?  923  ASN AAZA O   1 
ATOM   2701 C CB  . ASN A 1 381 ? 28.63900 15.58400 69.93400  1.000 99.13000  ?  923  ASN AAZA CB  1 
ATOM   2702 C CG  . ASN A 1 381 ? 27.48700 15.79900 70.91500  1.000 111.78000 ?  923  ASN AAZA CG  1 
ATOM   2703 O OD1 . ASN A 1 381 ? 27.60000 16.56200 71.89000  1.000 113.72000 ?  923  ASN AAZA OD1 1 
ATOM   2704 N ND2 . ASN A 1 381 ? 26.36700 15.13000 70.65600  1.000 114.62000 ?  923  ASN AAZA ND2 1 
ATOM   2705 N N   . PRO A 1 382 ? 31.75200 16.95300 69.64900  1.000 96.72000  ?  924  PRO AAZA N   1 
ATOM   2706 C CA  . PRO A 1 382 ? 33.10500 16.78500 69.12600  1.000 98.96000  ?  924  PRO AAZA CA  1 
ATOM   2707 C C   . PRO A 1 382 ? 33.34600 15.38100 68.56100  1.000 99.02000  ?  924  PRO AAZA C   1 
ATOM   2708 O O   . PRO A 1 382 ? 32.72300 14.45300 69.02400  1.000 100.24000 ?  924  PRO AAZA O   1 
ATOM   2709 C CB  . PRO A 1 382 ? 33.97100 17.00900 70.36900  1.000 97.59000  ?  924  PRO AAZA CB  1 
ATOM   2710 C CG  . PRO A 1 382 ? 33.17300 17.98400 71.19000  1.000 93.89000  ?  924  PRO AAZA CG  1 
ATOM   2711 C CD  . PRO A 1 382 ? 31.74900 17.51100 71.00800  1.000 89.87000  ?  924  PRO AAZA CD  1 
ATOM   2712 N N   . PRO A 1 383 ? 34.24700 15.21700 67.56900  1.000 102.91000 ?  925  PRO AAZA N   1 
ATOM   2713 C CA  . PRO A 1 383 ? 35.33600 16.16500 67.34300  1.000 98.71000  ?  925  PRO AAZA CA  1 
ATOM   2714 C C   . PRO A 1 383 ? 34.80500 17.42700 66.65500  1.000 97.76000  ?  925  PRO AAZA C   1 
ATOM   2715 O O   . PRO A 1 383 ? 33.72500 17.36400 66.10900  1.000 95.33000  ?  925  PRO AAZA O   1 
ATOM   2716 C CB  . PRO A 1 383 ? 36.27100 15.38700 66.41400  1.000 96.51000  ?  925  PRO AAZA CB  1 
ATOM   2717 C CG  . PRO A 1 383 ? 35.33900 14.50200 65.62400  1.000 100.07000 ?  925  PRO AAZA CG  1 
ATOM   2718 C CD  . PRO A 1 383 ? 34.26100 14.10900 66.61200  1.000 108.52000 ?  925  PRO AAZA CD  1 
ATOM   2719 N N   . CYS A 1 384 ? 35.56200 18.52700 66.69800  1.000 97.20000  ?  926  CYS AAZA N   1 
ATOM   2720 C CA  . CYS A 1 384 ? 35.03700 19.80100 66.14500  1.000 89.92000  ?  926  CYS AAZA CA  1 
ATOM   2721 C C   . CYS A 1 384 ? 36.15000 20.82600 65.94800  1.000 87.50000  ?  926  CYS AAZA C   1 
ATOM   2722 O O   . CYS A 1 384 ? 37.06600 20.84800 66.78200  1.000 85.77000  ?  926  CYS AAZA O   1 
ATOM   2723 C CB  . CYS A 1 384 ? 34.04200 20.40700 67.12400  1.000 88.20000  ?  926  CYS AAZA CB  1 
ATOM   2724 S SG  . CYS A 1 384 ? 33.27100 21.93300 66.53300  1.000 95.16000  ?  926  CYS AAZA SG  1 
ATOM   2725 N N   . VAL A 1 385 ? 36.09600 21.61000 64.86900  1.000 81.69000  ?  927  VAL AAZA N   1 
ATOM   2726 C CA  . VAL A 1 385 ? 37.02900 22.72700 64.69500  1.000 75.51000  ?  927  VAL AAZA CA  1 
ATOM   2727 C C   . VAL A 1 385 ? 36.21000 24.00300 64.65600  1.000 76.38000  ?  927  VAL AAZA C   1 
ATOM   2728 O O   . VAL A 1 385 ? 35.51600 24.27000 63.66300  1.000 75.44000  ?  927  VAL AAZA O   1 
ATOM   2729 C CB  . VAL A 1 385 ? 37.88700 22.62900 63.43100  1.000 69.13000  ?  927  VAL AAZA CB  1 
ATOM   2730 C CG1 . VAL A 1 385 ? 38.83000 23.78500 63.40700  1.000 67.59000  ?  927  VAL AAZA CG1 1 
ATOM   2731 C CG2 . VAL A 1 385 ? 38.63300 21.35200 63.39400  1.000 76.83000  ?  927  VAL AAZA CG2 1 
ATOM   2732 N N   . PRO A 1 386 ? 36.24500 24.80700 65.70400  1.000 74.08000  ?  928  PRO AAZA N   1 
ATOM   2733 C CA  . PRO A 1 386 ? 35.43200 26.01600 65.71300  1.000 71.99000  ?  928  PRO AAZA CA  1 
ATOM   2734 C C   . PRO A 1 386 ? 36.10200 27.14000 64.94000  1.000 70.55000  ?  928  PRO AAZA C   1 
ATOM   2735 O O   . PRO A 1 386 ? 37.29100 27.10000 64.60500  1.000 69.55000  ?  928  PRO AAZA O   1 
ATOM   2736 C CB  . PRO A 1 386 ? 35.29600 26.33700 67.20500  1.000 72.42000  ?  928  PRO AAZA CB  1 
ATOM   2737 C CG  . PRO A 1 386 ? 36.42900 25.67400 67.84600  1.000 69.12000  ?  928  PRO AAZA CG  1 
ATOM   2738 C CD  . PRO A 1 386 ? 36.93600 24.58400 66.98200  1.000 70.44000  ?  928  PRO AAZA CD  1 
ATOM   2739 N N   . PHE A 1 387 ? 35.29100 28.13700 64.61700  1.000 68.99000  ?  929  PHE AAZA N   1 
ATOM   2740 C CA  . PHE A 1 387 ? 35.80700 29.34300 63.99500  1.000 70.30000  ?  929  PHE AAZA CA  1 
ATOM   2741 C C   . PHE A 1 387 ? 36.37700 30.26400 65.06300  1.000 71.37000  ?  929  PHE AAZA C   1 
ATOM   2742 O O   . PHE A 1 387 ? 35.64400 30.74700 65.93600  1.000 70.98000  ?  929  PHE AAZA O   1 
ATOM   2743 C CB  . PHE A 1 387 ? 34.72200 30.05700 63.20600  1.000 71.64000  ?  929  PHE AAZA CB  1 
ATOM   2744 C CG  . PHE A 1 387 ? 35.16800 31.38400 62.67400  1.000 77.31000  ?  929  PHE AAZA CG  1 
ATOM   2745 C CD1 . PHE A 1 387 ? 36.31000 31.48300 61.89000  1.000 71.42000  ?  929  PHE AAZA CD1 1 
ATOM   2746 C CD2 . PHE A 1 387 ? 34.46600 32.54300 62.97900  1.000 74.82000  ?  929  PHE AAZA CD2 1 
ATOM   2747 C CE1 . PHE A 1 387 ? 36.72300 32.71100 61.41700  1.000 66.68000  ?  929  PHE AAZA CE1 1 
ATOM   2748 C CE2 . PHE A 1 387 ? 34.88400 33.76900 62.49200  1.000 70.88000  ?  929  PHE AAZA CE2 1 
ATOM   2749 C CZ  . PHE A 1 387 ? 36.01000 33.84800 61.71300  1.000 63.88000  ?  929  PHE AAZA CZ  1 
ATOM   2750 N N   . PHE A 1 388 ? 37.68200 30.52700 64.97700  1.000 72.03000  ?  930  PHE AAZA N   1 
ATOM   2751 C CA  . PHE A 1 388 ? 38.37700 31.19300 66.07400  1.000 68.60000  ?  930  PHE AAZA CA  1 
ATOM   2752 C C   . PHE A 1 388 ? 38.02100 32.67600 66.14600  1.000 68.98000  ?  930  PHE AAZA C   1 
ATOM   2753 O O   . PHE A 1 388 ? 38.01800 33.27300 67.23300  1.000 67.09000  ?  930  PHE AAZA O   1 
ATOM   2754 C CB  . PHE A 1 388 ? 39.88000 31.04900 65.87800  1.000 62.15000  ?  930  PHE AAZA CB  1 
ATOM   2755 C CG  . PHE A 1 388 ? 40.61200 30.80900 67.11600  1.000 59.39000  ?  930  PHE AAZA CG  1 
ATOM   2756 C CD1 . PHE A 1 388 ? 40.92900 31.83300 67.95600  1.000 66.31000  ?  930  PHE AAZA CD1 1 
ATOM   2757 C CD2 . PHE A 1 388 ? 40.86800 29.52000 67.52300  1.000 72.44000  ?  930  PHE AAZA CD2 1 
ATOM   2758 C CE1 . PHE A 1 388 ? 41.58300 31.58500 69.17000  1.000 73.12000  ?  930  PHE AAZA CE1 1 
ATOM   2759 C CE2 . PHE A 1 388 ? 41.54400 29.25000 68.72700  1.000 73.37000  ?  930  PHE AAZA CE2 1 
ATOM   2760 C CZ  . PHE A 1 388 ? 41.89500 30.28800 69.55600  1.000 68.50000  ?  930  PHE AAZA CZ  1 
ATOM   2761 N N   . GLY A 1 389 ? 37.70600 33.27500 64.99300  1.000 68.15000  ?  931  GLY AAZA N   1 
ATOM   2762 C CA  . GLY A 1 389 ? 37.51600 34.71400 64.87600  1.000 67.89000  ?  931  GLY AAZA CA  1 
ATOM   2763 C C   . GLY A 1 389 ? 36.49300 35.30100 65.82100  1.000 65.11000  ?  931  GLY AAZA C   1 
ATOM   2764 O O   . GLY A 1 389 ? 36.61300 36.47300 66.19400  1.000 60.43000  ?  931  GLY AAZA O   1 
ATOM   2765 N N   . ILE A 1 390 ? 35.48300 34.52400 66.21200  1.000 68.78000  ?  932  ILE AAZA N   1 
ATOM   2766 C CA  . ILE A 1 390 ? 34.49900 35.05600 67.15200  1.000 67.05000  ?  932  ILE AAZA CA  1 
ATOM   2767 C C   . ILE A 1 390 ? 35.08300 35.19000 68.54100  1.000 62.36000  ?  932  ILE AAZA C   1 
ATOM   2768 O O   . ILE A 1 390 ? 34.84300 36.19700 69.21400  1.000 59.68000  ?  932  ILE AAZA O   1 
ATOM   2769 C CB  . ILE A 1 390 ? 33.22300 34.21300 67.16500  1.000 65.06000  ?  932  ILE AAZA CB  1 
ATOM   2770 C CG1 . ILE A 1 390 ? 32.92800 33.76700 65.74800  1.000 69.07000  ?  932  ILE AAZA CG1 1 
ATOM   2771 C CG2 . ILE A 1 390 ? 32.06800 34.99800 67.77900  1.000 66.99000  ?  932  ILE AAZA CG2 1 
ATOM   2772 C CD1 . ILE A 1 390 ? 31.60500 33.13900 65.63800  1.000 74.63000  ?  932  ILE AAZA CD1 1 
ATOM   2773 N N   . TYR A 1 391 ? 35.87000 34.20200 68.99000  1.000 61.57000  ?  933  TYR AAZA N   1 
ATOM   2774 C CA  . TYR A 1 391 ? 36.47200 34.35800 70.30500  1.000 64.86000  ?  933  TYR AAZA CA  1 
ATOM   2775 C C   . TYR A 1 391 ? 37.47000 35.49700 70.30800  1.000 65.45000  ?  933  TYR AAZA C   1 
ATOM   2776 O O   . TYR A 1 391 ? 37.76300 36.06100 71.36900  1.000 59.49000  ?  933  TYR AAZA O   1 
ATOM   2777 C CB  . TYR A 1 391 ? 37.21200 33.11900 70.76900  1.000 66.29000  ?  933  TYR AAZA CB  1 
ATOM   2778 C CG  . TYR A 1 391 ? 36.37600 31.89300 70.84200  1.000 68.15000  ?  933  TYR AAZA CG  1 
ATOM   2779 C CD1 . TYR A 1 391 ? 35.28600 31.82500 71.67400  1.000 68.44000  ?  933  TYR AAZA CD1 1 
ATOM   2780 C CD2 . TYR A 1 391 ? 36.77600 30.73900 70.19400  1.000 70.38000  ?  933  TYR AAZA CD2 1 
ATOM   2781 C CE1 . TYR A 1 391 ? 34.53700 30.68500 71.73900  1.000 72.49000  ?  933  TYR AAZA CE1 1 
ATOM   2782 C CE2 . TYR A 1 391 ? 36.05500 29.59200 70.28900  1.000 69.89000  ?  933  TYR AAZA CE2 1 
ATOM   2783 C CZ  . TYR A 1 391 ? 34.93800 29.57200 71.05400  1.000 70.27000  ?  933  TYR AAZA CZ  1 
ATOM   2784 O OH  . TYR A 1 391 ? 34.20600 28.42900 71.13600  1.000 78.46000  ?  933  TYR AAZA OH  1 
ATOM   2785 N N   . LEU A 1 392 ? 38.02400 35.82600 69.14400  1.000 65.73000  ?  934  LEU AAZA N   1 
ATOM   2786 C CA  . LEU A 1 392 ? 38.96400 36.92600 69.10000  1.000 60.81000  ?  934  LEU AAZA CA  1 
ATOM   2787 C C   . LEU A 1 392 ? 38.26400 38.23500 69.40600  1.000 61.05000  ?  934  LEU AAZA C   1 
ATOM   2788 O O   . LEU A 1 392 ? 38.73500 39.00600 70.24600  1.000 64.41000  ?  934  LEU AAZA O   1 
ATOM   2789 C CB  . LEU A 1 392 ? 39.68400 36.96900 67.75400  1.000 59.15000  ?  934  LEU AAZA CB  1 
ATOM   2790 C CG  . LEU A 1 392 ? 40.61000 35.76300 67.55100  1.000 58.58000  ?  934  LEU AAZA CG  1 
ATOM   2791 C CD1 . LEU A 1 392 ? 41.71300 36.07800 66.56700  1.000 57.39000  ?  934  LEU AAZA CD1 1 
ATOM   2792 C CD2 . LEU A 1 392 ? 41.19900 35.28600 68.85900  1.000 58.86000  ?  934  LEU AAZA CD2 1 
ATOM   2793 N N   . THR A 1 393 ? 37.11500 38.48400 68.77800  1.000 61.38000  ?  935  THR AAZA N   1 
ATOM   2794 C CA  . THR A 1 393 ? 36.40800 39.73600 69.03100  1.000 60.21000  ?  935  THR AAZA CA  1 
ATOM   2795 C C   . THR A 1 393 ? 35.83600 39.76800 70.44000  1.000 67.01000  ?  935  THR AAZA C   1 
ATOM   2796 O O   . THR A 1 393 ? 35.90700 40.79600 71.12100  1.000 68.02000  ?  935  THR AAZA O   1 
ATOM   2797 C CB  . THR A 1 393 ? 35.29500 39.95400 68.01000  1.000 59.56000  ?  935  THR AAZA CB  1 
ATOM   2798 O OG1 . THR A 1 393 ? 35.81700 39.94400 66.67300  1.000 60.91000  ?  935  THR AAZA OG1 1 
ATOM   2799 C CG2 . THR A 1 393 ? 34.65100 41.26500 68.26000  1.000 56.64000  ?  935  THR AAZA CG2 1 
ATOM   2800 N N   . ASN A 1 394 ? 35.28700 38.64500 70.90900  1.000 68.33000  ?  936  ASN AAZA N   1 
ATOM   2801 C CA  . ASN A 1 394 ? 34.75400 38.59800 72.26700  1.000 65.66000  ?  936  ASN AAZA CA  1 
ATOM   2802 C C   . ASN A 1 394 ? 35.82000 38.88100 73.31100  1.000 67.57000  ?  936  ASN AAZA C   1 
ATOM   2803 O O   . ASN A 1 394 ? 35.50900 39.43600 74.36800  1.000 72.86000  ?  936  ASN AAZA O   1 
ATOM   2804 C CB  . ASN A 1 394 ? 34.13800 37.24100 72.55900  1.000 65.02000  ?  936  ASN AAZA CB  1 
ATOM   2805 C CG  . ASN A 1 394 ? 32.76500 37.11700 72.02500  1.000 72.42000  ?  936  ASN AAZA CG  1 
ATOM   2806 O OD1 . ASN A 1 394 ? 32.10500 38.12000 71.68900  1.000 72.87000  ?  936  ASN AAZA OD1 1 
ATOM   2807 N ND2 . ASN A 1 394 ? 32.30200 35.87800 71.93300  1.000 73.25000  ?  936  ASN AAZA ND2 1 
ATOM   2808 N N   . ILE A 1 395 ? 37.07100 38.52400 73.03900  1.000 65.14000  ?  937  ILE AAZA N   1 
ATOM   2809 C CA  . ILE A 1 395 ? 38.11900 38.70800 74.08400  1.000 66.75000  ?  937  ILE AAZA CA  1 
ATOM   2810 C C   . ILE A 1 395 ? 38.52700 40.18000 74.09500  1.000 70.62000  ?  937  ILE AAZA C   1 
ATOM   2811 O O   . ILE A 1 395 ? 38.70800 40.72900 75.18500  1.000 72.28000  ?  937  ILE AAZA O   1 
ATOM   2812 C CB  . ILE A 1 395 ? 39.32200 37.77800 73.85100  1.000 65.54000  ?  937  ILE AAZA CB  1 
ATOM   2813 C CG1 . ILE A 1 395 ? 38.96600 36.31700 74.13500  1.000 60.36000  ?  937  ILE AAZA CG1 1 
ATOM   2814 C CG2 . ILE A 1 395 ? 40.51900 38.23100 74.67000  1.000 62.98000  ?  937  ILE AAZA CG2 1 
ATOM   2815 C CD1 . ILE A 1 395 ? 40.10800 35.35800 73.91300  1.000 61.76000  ?  937  ILE AAZA CD1 1 
ATOM   2816 N N   . LEU A 1 396 ? 38.63300 40.79500 72.91900  1.000 67.62000  ?  938  LEU AAZA N   1 
ATOM   2817 C CA  . LEU A 1 396 ? 38.99100 42.23400 72.83500  1.000 69.56000  ?  938  LEU AAZA CA  1 
ATOM   2818 C C   . LEU A 1 396 ? 37.87500 43.05700 73.47300  1.000 72.37000  ?  938  LEU AAZA C   1 
ATOM   2819 O O   . LEU A 1 396 ? 38.14100 43.73800 74.47300  1.000 74.54000  ?  938  LEU AAZA O   1 
ATOM   2820 C CB  . LEU A 1 396 ? 39.15700 42.61400 71.36300  1.000 68.23000  ?  938  LEU AAZA CB  1 
ATOM   2821 C CG  . LEU A 1 396 ? 40.47300 43.29300 70.99400  1.000 65.39000  ?  938  LEU AAZA CG  1 
ATOM   2822 C CD1 . LEU A 1 396 ? 40.37900 43.92400 69.61600  1.000 61.89000  ?  938  LEU AAZA CD1 1 
ATOM   2823 C CD2 . LEU A 1 396 ? 40.85000 44.33700 72.03100  1.000 72.14000  ?  938  LEU AAZA CD2 1 
ATOM   2824 N N   . LYS A 1 397 ? 36.67000 42.97400 72.91700  1.000 68.85000  ?  939  LYS AAZA N   1 
ATOM   2825 C CA  . LYS A 1 397 ? 35.53200 43.76800 73.43800  1.000 72.97000  ?  939  LYS AAZA CA  1 
ATOM   2826 C C   . LYS A 1 397 ? 35.50100 43.64000 74.96100  1.000 72.60000  ?  939  LYS AAZA C   1 
ATOM   2827 O O   . LYS A 1 397 ? 35.37700 44.67200 75.63400  1.000 76.21000  ?  939  LYS AAZA O   1 
ATOM   2828 C CB  . LYS A 1 397 ? 34.22900 43.27000 72.81400  1.000 74.53000  ?  939  LYS AAZA CB  1 
ATOM   2829 C CG  . LYS A 1 397 ? 34.17100 43.28000 71.29400  1.000 66.97000  ?  939  LYS AAZA CG  1 
ATOM   2830 C CD  . LYS A 1 397 ? 33.36500 44.42900 70.73600  1.000 75.61000  ?  939  LYS AAZA CD  1 
ATOM   2831 C CE  . LYS A 1 397 ? 32.81700 44.14500 69.35500  1.000 75.83000  ?  939  LYS AAZA CE  1 
ATOM   2832 N NZ  . LYS A 1 397 ? 31.89900 42.98200 69.36000  1.000 70.41000  ?  939  LYS AAZA NZ  1 
ATOM   2833 N N   . THR A 1 398 ? 35.61700 42.41800 75.47600  1.000 68.17000  ?  940  THR AAZA N   1 
ATOM   2834 C CA  . THR A 1 398 ? 35.55200 42.21700 76.92300  1.000 69.99000  ?  940  THR AAZA CA  1 
ATOM   2835 C C   . THR A 1 398 ? 36.65100 42.96400 77.65600  1.000 68.61000  ?  940  THR AAZA C   1 
ATOM   2836 O O   . THR A 1 398 ? 36.41300 43.55400 78.70800  1.000 72.47000  ?  940  THR AAZA O   1 
ATOM   2837 C CB  . THR A 1 398 ? 35.65100 40.74200 77.26200  1.000 68.98000  ?  940  THR AAZA CB  1 
ATOM   2838 O OG1 . THR A 1 398 ? 34.53800 40.06300 76.68300  1.000 75.70000  ?  940  THR AAZA OG1 1 
ATOM   2839 C CG2 . THR A 1 398 ? 35.60400 40.56200 78.74700  1.000 65.82000  ?  940  THR AAZA CG2 1 
ATOM   2840 N N   . GLU A 1 399 ? 37.86600 42.91400 77.14600  1.000 73.64000  ?  941  GLU AAZA N   1 
ATOM   2841 C CA  . GLU A 1 399 ? 38.97500 43.58800 77.79900  1.000 74.74000  ?  941  GLU AAZA CA  1 
ATOM   2842 C C   . GLU A 1 399 ? 38.91300 45.09000 77.62200  1.000 75.37000  ?  941  GLU AAZA C   1 
ATOM   2843 O O   . GLU A 1 399 ? 39.63000 45.80600 78.32500  1.000 81.22000  ?  941  GLU AAZA O   1 
ATOM   2844 C CB  . GLU A 1 399 ? 40.30200 43.10500 77.22600  1.000 75.11000  ?  941  GLU AAZA CB  1 
ATOM   2845 C CG  . GLU A 1 399 ? 40.53100 41.61800 77.26200  1.000 73.58000  ?  941  GLU AAZA CG  1 
ATOM   2846 C CD  . GLU A 1 399 ? 41.98300 41.25800 77.50700  1.000 82.19000  ?  941  GLU AAZA CD  1 
ATOM   2847 O OE1 . GLU A 1 399 ? 42.83100 41.77400 76.72100  1.000 82.02000  ?  941  GLU AAZA OE1 1 
ATOM   2848 O OE2 . GLU A 1 399 ? 42.26300 40.38900 78.38700  1.000 75.15000  ?  941  GLU AAZA OE2 1 
ATOM   2849 N N   . GLU A 1 400 ? 38.10800 45.58100 76.68000  1.000 73.36000  ?  942  GLU AAZA N   1 
ATOM   2850 C CA  . GLU A 1 400 ? 38.07000 47.00400 76.36200  1.000 83.07000  ?  942  GLU AAZA CA  1 
ATOM   2851 C C   . GLU A 1 400 ? 36.73700 47.66200 76.68700  1.000 81.72000  ?  942  GLU AAZA C   1 
ATOM   2852 O O   . GLU A 1 400 ? 36.56200 48.85000 76.39400  1.000 86.86000  ?  942  GLU AAZA O   1 
ATOM   2853 C CB  . GLU A 1 400 ? 38.43200 47.23700 74.88800  1.000 81.05000  ?  942  GLU AAZA CB  1 
ATOM   2854 C CG  . GLU A 1 400 ? 39.77400 46.60400 74.52500  1.000 91.44000  ?  942  GLU AAZA CG  1 
ATOM   2855 C CD  . GLU A 1 400 ? 40.64500 47.49700 73.64500  1.000 106.92000 ?  942  GLU AAZA CD  1 
ATOM   2856 O OE1 . GLU A 1 400 ? 40.05500 48.32300 72.90000  1.000 112.69000 ?  942  GLU AAZA OE1 1 
ATOM   2857 O OE2 . GLU A 1 400 ? 41.90500 47.37300 73.70700  1.000 106.65000 ?  942  GLU AAZA OE2 1 
ATOM   2858 N N   . GLY A 1 401 ? 35.80900 46.94200 77.30100  1.000 77.45000  ?  943  GLY AAZA N   1 
ATOM   2859 C CA  . GLY A 1 401 ? 34.52100 47.50700 77.63900  1.000 80.18000  ?  943  GLY AAZA CA  1 
ATOM   2860 C C   . GLY A 1 401 ? 34.27500 47.35700 79.12100  1.000 83.87000  ?  943  GLY AAZA C   1 
ATOM   2861 O O   . GLY A 1 401 ? 33.18400 47.62700 79.63800  1.000 92.55000  ?  943  GLY AAZA O   1 
ATOM   2862 N N   . ASN A 1 402 ? 35.30400 46.90200 79.81000  1.000 73.49000  ?  944  ASN AAZA N   1 
ATOM   2863 C CA  . ASN A 1 402 ? 35.24700 46.76400 81.23800  1.000 77.30000  ?  944  ASN AAZA CA  1 
ATOM   2864 C C   . ASN A 1 402 ? 36.49900 47.40000 81.81500  1.000 79.57000  ?  944  ASN AAZA C   1 
ATOM   2865 O O   . ASN A 1 402 ? 37.59200 47.23700 81.26300  1.000 79.10000  ?  944  ASN AAZA O   1 
ATOM   2866 C CB  . ASN A 1 402 ? 35.12800 45.29500 81.64900  1.000 79.15000  ?  944  ASN AAZA CB  1 
ATOM   2867 C CG  . ASN A 1 402 ? 33.88200 44.63900 81.09200  1.000 83.47000  ?  944  ASN AAZA CG  1 
ATOM   2868 O OD1 . ASN A 1 402 ? 32.77000 44.93600 81.52000  1.000 93.44000  ?  944  ASN AAZA OD1 1 
ATOM   2869 N ND2 . ASN A 1 402 ? 34.05600 43.76900 80.11700  1.000 82.06000  ?  944  ASN AAZA ND2 1 
ATOM   2870 N N   . PRO A 1 403 ? 36.36500 48.16000 82.89300  1.000 79.02000  ?  945  PRO AAZA N   1 
ATOM   2871 C CA  . PRO A 1 403 ? 37.48700 48.97200 83.35100  1.000 78.10000  ?  945  PRO AAZA CA  1 
ATOM   2872 C C   . PRO A 1 403 ? 38.56700 48.08100 83.93800  1.000 77.64000  ?  945  PRO AAZA C   1 
ATOM   2873 O O   . PRO A 1 403 ? 38.32700 46.95100 84.36100  1.000 77.22000  ?  945  PRO AAZA O   1 
ATOM   2874 C CB  . PRO A 1 403 ? 36.85800 49.88500 84.40200  1.000 79.24000  ?  945  PRO AAZA CB  1 
ATOM   2875 C CG  . PRO A 1 403 ? 35.70500 49.09100 84.92200  1.000 87.15000  ?  945  PRO AAZA CG  1 
ATOM   2876 C CD  . PRO A 1 403 ? 35.20500 48.24100 83.79600  1.000 79.93000  ?  945  PRO AAZA CD  1 
ATOM   2877 N N   . GLU A 1 404 ? 39.78700 48.59100 83.92100  1.000 77.89000  ?  946  GLU AAZA N   1 
ATOM   2878 C CA  . GLU A 1 404 ? 40.88100 47.77700 84.41400  1.000 79.60000  ?  946  GLU AAZA CA  1 
ATOM   2879 C C   . GLU A 1 404 ? 40.96500 47.79600 85.93800  1.000 83.34000  ?  946  GLU AAZA C   1 
ATOM   2880 O O   . GLU A 1 404 ? 41.27700 46.76400 86.54800  1.000 77.42000  ?  946  GLU AAZA O   1 
ATOM   2881 C CB  . GLU A 1 404 ? 42.18000 48.24500 83.78000  1.000 78.20000  ?  946  GLU AAZA CB  1 
ATOM   2882 C CG  . GLU A 1 404 ? 43.20400 47.17000 83.72200  1.000 88.59000  ?  946  GLU AAZA CG  1 
ATOM   2883 C CD  . GLU A 1 404 ? 43.98600 47.15700 82.42400  1.000 105.84000 ?  946  GLU AAZA CD  1 
ATOM   2884 O OE1 . GLU A 1 404 ? 44.80900 48.08700 82.18700  1.000 114.78000 ?  946  GLU AAZA OE1 1 
ATOM   2885 O OE2 . GLU A 1 404 ? 43.79700 46.19100 81.65500  1.000 111.39000 ?  946  GLU AAZA OE2 1 
ATOM   2886 N N   . VAL A 1 405 ? 40.64000 48.94300 86.54100  1.000 87.34000  ?  947  VAL AAZA N   1 
ATOM   2887 C CA  . VAL A 1 405 ? 40.75000 49.09300 88.02000  1.000 78.48000  ?  947  VAL AAZA CA  1 
ATOM   2888 C C   . VAL A 1 405 ? 39.48900 49.76100 88.56000  1.000 82.13000  ?  947  VAL AAZA C   1 
ATOM   2889 O O   . VAL A 1 405 ? 39.52800 50.97500 88.79200  1.000 92.59000  ?  947  VAL AAZA O   1 
ATOM   2890 C CB  . VAL A 1 405 ? 41.98800 49.92100 88.40100  1.000 81.15000  ?  947  VAL AAZA CB  1 
ATOM   2891 C CG1 . VAL A 1 405 ? 43.19400 49.03700 88.67100  1.000 80.68000  ?  947  VAL AAZA CG1 1 
ATOM   2892 C CG2 . VAL A 1 405 ? 42.31500 50.96300 87.34500  1.000 93.23000  ?  947  VAL AAZA CG2 1 
ATOM   2893 N N   . LEU A 1 406 ? 38.42200 48.99600 88.76200  1.000 79.87000  ?  948  LEU AAZA N   1 
ATOM   2894 C CA  . LEU A 1 406 ? 37.20500 49.56500 89.39100  1.000 94.97000  ?  948  LEU AAZA CA  1 
ATOM   2895 C C   . LEU A 1 406 ? 37.62400 50.30500 90.66300  1.000 87.58000  ?  948  LEU AAZA C   1 
ATOM   2896 O O   . LEU A 1 406 ? 38.27600 49.68500 91.51300  1.000 76.20000  ?  948  LEU AAZA O   1 
ATOM   2897 C CB  . LEU A 1 406 ? 36.24400 48.41700 89.70600  1.000 83.08000  ?  948  LEU AAZA CB  1 
ATOM   2898 C CG  . LEU A 1 406 ? 34.97200 48.80300 90.45200  1.000 75.04000  ?  948  LEU AAZA CG  1 
ATOM   2899 C CD1 . LEU A 1 406 ? 34.25600 49.94000 89.74200  1.000 88.83000  ?  948  LEU AAZA CD1 1 
ATOM   2900 C CD2 . LEU A 1 406 ? 34.05300 47.60100 90.59200  1.000 68.85000  ?  948  LEU AAZA CD2 1 
ATOM   2901 N N   . LYS A 1 407 ? 37.27300 51.58600 90.77700  1.000 95.42000  ?  949  LYS AAZA N   1 
ATOM   2902 C CA  . LYS A 1 407 ? 37.68000 52.40200 91.95000  1.000 92.41000  ?  949  LYS AAZA CA  1 
ATOM   2903 C C   . LYS A 1 407 ? 36.49600 52.53000 92.90400  1.000 90.44000  ?  949  LYS AAZA C   1 
ATOM   2904 O O   . LYS A 1 407 ? 35.36700 52.69400 92.42000  1.000 88.21000  ?  949  LYS AAZA O   1 
ATOM   2905 C CB  . LYS A 1 407 ? 38.13600 53.79100 91.50100  1.000 92.34000  ?  949  LYS AAZA CB  1 
ATOM   2906 C CG  . LYS A 1 407 ? 39.62800 54.05700 91.62800  1.000 101.38000 ?  949  LYS AAZA CG  1 
ATOM   2907 C CD  . LYS A 1 407 ? 39.95400 55.17200 92.59400  1.000 102.99000 ?  949  LYS AAZA CD  1 
ATOM   2908 C CE  . LYS A 1 407 ? 41.13900 56.00600 92.15700  1.000 109.15000 ?  949  LYS AAZA CE  1 
ATOM   2909 N NZ  . LYS A 1 407 ? 42.18100 56.07000 93.20900  1.000 110.79000 ?  949  LYS AAZA NZ  1 
ATOM   2910 N N   . ARG A 1 408 ? 36.75900 52.50500 94.21300  1.000 95.51000  ?  950  ARG AAZA N   1 
ATOM   2911 C CA  . ARG A 1 408 ? 35.68400 52.63900 95.23300  1.000 99.10000  ?  950  ARG AAZA CA  1 
ATOM   2912 C C   . ARG A 1 408 ? 36.23600 53.31000 96.49300  1.000 100.88000 ?  950  ARG AAZA C   1 
ATOM   2913 O O   . ARG A 1 408 ? 37.31700 52.89900 96.94400  1.000 99.56000  ?  950  ARG AAZA O   1 
ATOM   2914 C CB  . ARG A 1 408 ? 35.11600 51.27100 95.61900  1.000 97.66000  ?  950  ARG AAZA CB  1 
ATOM   2915 C CG  . ARG A 1 408 ? 33.73200 50.97100 95.06500  1.000 94.95000  ?  950  ARG AAZA CG  1 
ATOM   2916 C CD  . ARG A 1 408 ? 33.78800 50.31800 93.69900  1.000 96.64000  ?  950  ARG AAZA CD  1 
ATOM   2917 N NE  . ARG A 1 408 ? 32.60300 49.51800 93.43500  1.000 98.29000  ?  950  ARG AAZA NE  1 
ATOM   2918 C CZ  . ARG A 1 408 ? 31.77100 49.71700 92.42200  1.000 99.00000  ?  950  ARG AAZA CZ  1 
ATOM   2919 N NH1 . ARG A 1 408 ? 31.85500 50.82300 91.70600  1.000 92.38000  ?  950  ARG AAZA NH1 1 
ATOM   2920 N NH2 . ARG A 1 408 ? 30.85600 48.80900 92.12800  1.000 101.21000 ?  950  ARG AAZA NH2 1 
ATOM   2921 N N   . HIS A 1 409 ? 35.53300 54.31500 97.01900  1.000 103.99000 ?  951  HIS AAZA N   1 
ATOM   2922 C CA  . HIS A 1 409 ? 35.93900 54.99000 98.28300  1.000 110.94000 ?  951  HIS AAZA CA  1 
ATOM   2923 C C   . HIS A 1 409 ? 37.21400 55.81100 98.08500  1.000 105.45000 ?  951  HIS AAZA C   1 
ATOM   2924 O O   . HIS A 1 409 ? 37.64700 56.47100 99.04800  1.000 100.13000 ?  951  HIS AAZA O   1 
ATOM   2925 C CB  . HIS A 1 409 ? 36.10700 53.97300 99.41300  1.000 116.93000 ?  951  HIS AAZA CB  1 
ATOM   2926 C CG  . HIS A 1 409 ? 35.13800 54.17300 100.52600 1.000 125.04000 ?  951  HIS AAZA CG  1 
ATOM   2927 N ND1 . HIS A 1 409 ? 35.52700 54.45200 101.81800 1.000 129.09000 ?  951  HIS AAZA ND1 1 
ATOM   2928 C CD2 . HIS A 1 409 ? 33.80100 54.14600 100.53800 1.000 129.53000 ?  951  HIS AAZA CD2 1 
ATOM   2929 C CE1 . HIS A 1 409 ? 34.45100 54.58000 102.57800 1.000 137.92000 ?  951  HIS AAZA CE1 1 
ATOM   2930 N NE2 . HIS A 1 409 ? 33.39100 54.39800 101.82000 1.000 143.92000 ?  951  HIS AAZA NE2 1 
ATOM   2931 N N   . GLY A 1 410 ? 37.79000 55.78300 96.88500  1.000 103.12000 ?  952  GLY AAZA N   1 
ATOM   2932 C CA  . GLY A 1 410 ? 38.97200 56.61900 96.60700  1.000 100.40000 ?  952  GLY AAZA CA  1 
ATOM   2933 C C   . GLY A 1 410 ? 40.21300 55.79400 96.33500  1.000 100.86000 ?  952  GLY AAZA C   1 
ATOM   2934 O O   . GLY A 1 410 ? 41.27700 56.38800 96.09900  1.000 97.62000  ?  952  GLY AAZA O   1 
ATOM   2935 N N   . LYS A 1 411 ? 40.07400 54.47100 96.35700  1.000 98.10000  ?  953  LYS AAZA N   1 
ATOM   2936 C CA  . LYS A 1 411 ? 41.23000 53.59000 96.07000  1.000 105.07000 ?  953  LYS AAZA CA  1 
ATOM   2937 C C   . LYS A 1 411 ? 40.88700 52.67200 94.89900  1.000 100.79000 ?  953  LYS AAZA C   1 
ATOM   2938 O O   . LYS A 1 411 ? 39.69500 52.37800 94.71300  1.000 94.36000  ?  953  LYS AAZA O   1 
ATOM   2939 C CB  . LYS A 1 411 ? 41.60300 52.78200 97.31300  1.000 107.53000 ?  953  LYS AAZA CB  1 
ATOM   2940 C CG  . LYS A 1 411 ? 42.86300 51.94200 97.15700  1.000 108.86000 ?  953  LYS AAZA CG  1 
ATOM   2941 C CD  . LYS A 1 411 ? 44.01500 52.73200 96.57400  1.000 103.76000 ?  953  LYS AAZA CD  1 
ATOM   2942 C CE  . LYS A 1 411 ? 45.09600 51.85700 95.97700  1.000 101.17000 ?  953  LYS AAZA CE  1 
ATOM   2943 N NZ  . LYS A 1 411 ? 44.57700 51.04200 94.85300  1.000 94.21000  ?  953  LYS AAZA NZ  1 
ATOM   2944 N N   . GLU A 1 412 ? 41.90100 52.25400 94.13900  1.000 97.57000  ?  954  GLU AAZA N   1 
ATOM   2945 C CA  . GLU A 1 412 ? 41.66400 51.38000 93.01500  1.000 97.13000  ?  954  GLU AAZA CA  1 
ATOM   2946 C C   . GLU A 1 412 ? 41.61300 49.94200 93.48500  1.000 92.34000  ?  954  GLU AAZA C   1 
ATOM   2947 O O   . GLU A 1 412 ? 42.25200 49.56700 94.46900  1.000 89.26000  ?  954  GLU AAZA O   1 
ATOM   2948 C CB  . GLU A 1 412 ? 42.77100 51.54700 91.98100  1.000 100.98000 ?  954  GLU AAZA CB  1 
ATOM   2949 C CG  . GLU A 1 412 ? 43.00200 52.97200 91.59100  1.000 100.38000 ?  954  GLU AAZA CG  1 
ATOM   2950 C CD  . GLU A 1 412 ? 44.34600 53.16700 90.96200  1.000 107.25000 ?  954  GLU AAZA CD  1 
ATOM   2951 O OE1 . GLU A 1 412 ? 45.18500 52.24000 91.06400  1.000 104.75000 ?  954  GLU AAZA OE1 1 
ATOM   2952 O OE2 . GLU A 1 412 ? 44.55900 54.24700 90.36800  1.000 117.97000 ?  954  GLU AAZA OE2 1 
ATOM   2953 N N   . LEU A 1 413 ? 40.76900 49.16000 92.82900  1.000 88.17000  ?  955  LEU AAZA N   1 
ATOM   2954 C CA  . LEU A 1 413 ? 40.74300 47.71100 93.12000  1.000 82.36000  ?  955  LEU AAZA CA  1 
ATOM   2955 C C   . LEU A 1 413 ? 41.12500 47.05500 91.79500  1.000 81.24000  ?  955  LEU AAZA C   1 
ATOM   2956 O O   . LEU A 1 413 ? 41.18500 47.77900 90.80400  1.000 82.55000  ?  955  LEU AAZA O   1 
ATOM   2957 C CB  . LEU A 1 413 ? 39.34200 47.32600 93.59400  1.000 81.01000  ?  955  LEU AAZA CB  1 
ATOM   2958 C CG  . LEU A 1 413 ? 39.03000 47.67000 95.05000  1.000 81.36000  ?  955  LEU AAZA CG  1 
ATOM   2959 C CD1 . LEU A 1 413 ? 38.77600 49.15800 95.21900  1.000 89.40000  ?  955  LEU AAZA CD1 1 
ATOM   2960 C CD2 . LEU A 1 413 ? 37.84000 46.87200 95.55400  1.000 78.04000  ?  955  LEU AAZA CD2 1 
ATOM   2961 N N   . ILE A 1 414 ? 41.46900 45.77700 91.77100  1.000 73.23000  ?  956  ILE AAZA N   1 
ATOM   2962 C CA  . ILE A 1 414 ? 41.78000 45.19400 90.44100  1.000 72.65000  ?  956  ILE AAZA CA  1 
ATOM   2963 C C   . ILE A 1 414 ? 40.48000 44.58900 89.93500  1.000 75.62000  ?  956  ILE AAZA C   1 
ATOM   2964 O O   . ILE A 1 414 ? 39.91600 43.75000 90.64600  1.000 75.21000  ?  956  ILE AAZA O   1 
ATOM   2965 C CB  . ILE A 1 414 ? 42.91800 44.16800 90.54600  1.000 72.03000  ?  956  ILE AAZA CB  1 
ATOM   2966 C CG1 . ILE A 1 414 ? 44.19700 44.81900 91.07300  1.000 68.32000  ?  956  ILE AAZA CG1 1 
ATOM   2967 C CG2 . ILE A 1 414 ? 43.13800 43.48000 89.21200  1.000 70.47000  ?  956  ILE AAZA CG2 1 
ATOM   2968 C CD1 . ILE A 1 414 ? 45.30500 43.84300 91.36400  1.000 77.98000  ?  956  ILE AAZA CD1 1 
ATOM   2969 N N   . ASN A 1 415 ? 39.95600 45.02100 88.78700  1.000 75.86000  ?  957  ASN AAZA N   1 
ATOM   2970 C CA  . ASN A 1 415 ? 38.71700 44.38500 88.26400  1.000 73.46000  ?  957  ASN AAZA CA  1 
ATOM   2971 C C   . ASN A 1 415 ? 39.00600 42.93100 87.91100  1.000 72.39000  ?  957  ASN AAZA C   1 
ATOM   2972 O O   . ASN A 1 415 ? 39.58800 42.69700 86.84900  1.000 73.73000  ?  957  ASN AAZA O   1 
ATOM   2973 C CB  . ASN A 1 415 ? 38.11600 45.11800 87.06600  1.000 75.06000  ?  957  ASN AAZA CB  1 
ATOM   2974 C CG  . ASN A 1 415 ? 36.71100 44.66000 86.74400  1.000 74.71000  ?  957  ASN AAZA CG  1 
ATOM   2975 O OD1 . ASN A 1 415 ? 36.17900 43.77100 87.40200  1.000 76.44000  ?  957  ASN AAZA OD1 1 
ATOM   2976 N ND2 . ASN A 1 415 ? 36.10300 45.26300 85.73700  1.000 71.69000  ?  957  ASN AAZA ND2 1 
ATOM   2977 N N   . PHE A 1 416 ? 38.59700 42.00600 88.77200  1.000 74.35000  ?  958  PHE AAZA N   1 
ATOM   2978 C CA  . PHE A 1 416 ? 38.85700 40.59400 88.55200  1.000 68.24000  ?  958  PHE AAZA CA  1 
ATOM   2979 C C   . PHE A 1 416 ? 37.53700 40.19400 87.94300  1.000 69.00000  ?  958  PHE AAZA C   1 
ATOM   2980 O O   . PHE A 1 416 ? 37.61500 39.13000 87.32500  1.000 68.20000  ?  958  PHE AAZA O   1 
ATOM   2981 C CB  . PHE A 1 416 ? 38.99900 39.97800 89.93700  1.000 66.12000  ?  958  PHE AAZA CB  1 
ATOM   2982 C CG  . PHE A 1 416 ? 39.53200 38.60800 89.73400  1.000 62.90000  ?  958  PHE AAZA CG  1 
ATOM   2983 C CD1 . PHE A 1 416 ? 40.87800 38.40600 89.55100  1.000 58.45000  ?  958  PHE AAZA CD1 1 
ATOM   2984 C CD2 . PHE A 1 416 ? 38.68300 37.50800 89.76200  1.000 68.77000  ?  958  PHE AAZA CD2 1 
ATOM   2985 C CE1 . PHE A 1 416 ? 41.37400 37.13500 89.38300  1.000 69.18000  ?  958  PHE AAZA CE1 1 
ATOM   2986 C CE2 . PHE A 1 416 ? 39.16900 36.22200 89.59500  1.000 69.41000  ?  958  PHE AAZA CE2 1 
ATOM   2987 C CZ  . PHE A 1 416 ? 40.51900 36.03300 89.40400  1.000 71.97000  ?  958  PHE AAZA CZ  1 
ATOM   2988 N N   . SER A 1 417 ? 36.40600 40.88600 88.04100  1.000 72.26000  ?  959  SER AAZA N   1 
ATOM   2989 C CA  . SER A 1 417 ? 35.21000 40.43200 87.34600  1.000 74.70000  ?  959  SER AAZA CA  1 
ATOM   2990 C C   . SER A 1 417 ? 35.44800 40.42200 85.83500  1.000 74.18000  ?  959  SER AAZA C   1 
ATOM   2991 O O   . SER A 1 417 ? 35.07800 39.46800 85.13700  1.000 70.07000  ?  959  SER AAZA O   1 
ATOM   2992 C CB  . SER A 1 417 ? 34.03800 41.33900 87.73500  1.000 80.76000  ?  959  SER AAZA CB  1 
ATOM   2993 O OG  . SER A 1 417 ? 32.79400 40.65200 87.74300  1.000 91.45000  ?  959  SER AAZA OG  1 
ATOM   2994 N N   . LYS A 1 418 ? 36.12200 41.46300 85.32900  1.000 77.23000  ?  960  LYS AAZA N   1 
ATOM   2995 C CA  . LYS A 1 418 ? 36.50300 41.53300 83.92000  1.000 73.10000  ?  960  LYS AAZA CA  1 
ATOM   2996 C C   . LYS A 1 418 ? 37.45000 40.40700 83.53800  1.000 68.27000  ?  960  LYS AAZA C   1 
ATOM   2997 O O   . LYS A 1 418 ? 37.31700 39.82600 82.45900  1.000 68.64000  ?  960  LYS AAZA O   1 
ATOM   2998 C CB  . LYS A 1 418 ? 37.12900 42.89800 83.63200  1.000 72.63000  ?  960  LYS AAZA CB  1 
ATOM   2999 C CG  . LYS A 1 418 ? 38.12000 42.97300 82.50600  1.000 68.77000  ?  960  LYS AAZA CG  1 
ATOM   3000 C CD  . LYS A 1 418 ? 38.70200 44.38000 82.44400  1.000 73.94000  ?  960  LYS AAZA CD  1 
ATOM   3001 C CE  . LYS A 1 418 ? 39.89800 44.47900 81.50600  1.000 81.53000  ?  960  LYS AAZA CE  1 
ATOM   3002 N NZ  . LYS A 1 418 ? 40.53700 45.82400 81.54900  1.000 81.38000  ?  960  LYS AAZA NZ  1 
ATOM   3003 N N   . ARG A 1 419 ? 38.40600 40.08000 84.41300  1.000 68.52000  ?  961  ARG AAZA N   1 
ATOM   3004 C CA  . ARG A 1 419 ? 39.32300 38.97300 84.15300  1.000 66.03000  ?  961  ARG AAZA CA  1 
ATOM   3005 C C   . ARG A 1 419 ? 38.59100 37.64100 84.14300  1.000 68.05000  ?  961  ARG AAZA C   1 
ATOM   3006 O O   . ARG A 1 419 ? 38.89800 36.77000 83.32900  1.000 69.58000  ?  961  ARG AAZA O   1 
ATOM   3007 C CB  . ARG A 1 419 ? 40.43700 38.93900 85.19300  1.000 59.21000  ?  961  ARG AAZA CB  1 
ATOM   3008 C CG  . ARG A 1 419 ? 41.61600 39.80300 84.84100  1.000 66.13000  ?  961  ARG AAZA CG  1 
ATOM   3009 C CD  . ARG A 1 419 ? 41.27700 41.29300 85.01100  1.000 72.12000  ?  961  ARG AAZA CD  1 
ATOM   3010 N NE  . ARG A 1 419 ? 42.38100 42.18600 84.66900  1.000 78.85000  ?  961  ARG AAZA NE  1 
ATOM   3011 C CZ  . ARG A 1 419 ? 42.54700 43.41600 85.14700  1.000 83.77000  ?  961  ARG AAZA CZ  1 
ATOM   3012 N NH1 . ARG A 1 419 ? 41.68400 43.95900 85.99700  1.000 80.50000  ?  961  ARG AAZA NH1 1 
ATOM   3013 N NH2 . ARG A 1 419 ? 43.61500 44.11900 84.77100  1.000 85.85000  ?  961  ARG AAZA NH2 1 
ATOM   3014 N N   . ARG A 1 420 ? 37.62200 37.45500 85.03200  1.000 67.35000  ?  962  ARG AAZA N   1 
ATOM   3015 C CA  . ARG A 1 420 ? 36.90100 36.19000 85.03400  1.000 69.64000  ?  962  ARG AAZA CA  1 
ATOM   3016 C C   . ARG A 1 420 ? 36.21900 35.94200 83.69800  1.000 69.54000  ?  962  ARG AAZA C   1 
ATOM   3017 O O   . ARG A 1 420 ? 36.16500 34.80200 83.23400  1.000 68.90000  ?  962  ARG AAZA O   1 
ATOM   3018 C CB  . ARG A 1 420 ? 35.87400 36.16100 86.15900  1.000 73.11000  ?  962  ARG AAZA CB  1 
ATOM   3019 C CG  . ARG A 1 420 ? 35.16700 34.83000 86.31100  1.000 71.31000  ?  962  ARG AAZA CG  1 
ATOM   3020 C CD  . ARG A 1 420 ? 34.02500 34.92700 87.31100  1.000 77.74000  ?  962  ARG AAZA CD  1 
ATOM   3021 N NE  . ARG A 1 420 ? 34.37300 35.77900 88.43900  1.000 76.19000  ?  962  ARG AAZA NE  1 
ATOM   3022 C CZ  . ARG A 1 420 ? 35.27400 35.46700 89.35700  1.000 81.32000  ?  962  ARG AAZA CZ  1 
ATOM   3023 N NH1 . ARG A 1 420 ? 35.96500 34.32900 89.29000  1.000 74.33000  ?  962  ARG AAZA NH1 1 
ATOM   3024 N NH2 . ARG A 1 420 ? 35.52000 36.33800 90.33900  1.000 79.39000  ?  962  ARG AAZA NH2 1 
ATOM   3025 N N   . LYS A 1 421 ? 35.69900 36.99800 83.06000  1.000 71.80000  ?  963  LYS AAZA N   1 
ATOM   3026 C CA  . LYS A 1 421 ? 34.98600 36.82300 81.79000  1.000 75.64000  ?  963  LYS AAZA CA  1 
ATOM   3027 C C   . LYS A 1 421 ? 35.93600 36.37700 80.67900  1.000 74.52000  ?  963  LYS AAZA C   1 
ATOM   3028 O O   . LYS A 1 421 ? 35.61400 35.46800 79.89900  1.000 70.05000  ?  963  LYS AAZA O   1 
ATOM   3029 C CB  . LYS A 1 421 ? 34.27300 38.12100 81.39300  1.000 74.16000  ?  963  LYS AAZA CB  1 
ATOM   3030 C CG  . LYS A 1 421 ? 33.14800 38.55900 82.33400  1.000 82.59000  ?  963  LYS AAZA CG  1 
ATOM   3031 C CD  . LYS A 1 421 ? 32.27800 39.66600 81.71800  1.000 96.57000  ?  963  LYS AAZA CD  1 
ATOM   3032 C CE  . LYS A 1 421 ? 31.54800 40.49900 82.77900  1.000 99.03000  ?  963  LYS AAZA CE  1 
ATOM   3033 N NZ  . LYS A 1 421 ? 32.45100 41.47400 83.47800  1.000 91.82000  ?  963  LYS AAZA NZ  1 
ATOM   3034 N N   . VAL A 1 422 ? 37.11100 37.01300 80.59900  1.000 74.14000  ?  964  VAL AAZA N   1 
ATOM   3035 C CA  . VAL A 1 422 ? 38.14600 36.61000 79.65200  1.000 69.41000  ?  964  VAL AAZA CA  1 
ATOM   3036 C C   . VAL A 1 422 ? 38.52600 35.15300 79.86100  1.000 69.98000  ?  964  VAL AAZA C   1 
ATOM   3037 O O   . VAL A 1 422 ? 38.64700 34.38700 78.90200  1.000 69.85000  ?  964  VAL AAZA O   1 
ATOM   3038 C CB  . VAL A 1 422 ? 39.36900 37.52800 79.79600  1.000 67.97000  ?  964  VAL AAZA CB  1 
ATOM   3039 C CG1 . VAL A 1 422 ? 40.48500 37.09000 78.85600  1.000 63.05000  ?  964  VAL AAZA CG1 1 
ATOM   3040 C CG2 . VAL A 1 422 ? 38.95900 38.96400 79.56000  1.000 68.22000  ?  964  VAL AAZA CG2 1 
ATOM   3041 N N   . ALA A 1 423 ? 38.72900 34.75100 81.11900  1.000 72.36000  ?  965  ALA AAZA N   1 
ATOM   3042 C CA  . ALA A 1 423 ? 39.04100 33.36000 81.43400  1.000 67.02000  ?  965  ALA AAZA CA  1 
ATOM   3043 C C   . ALA A 1 423 ? 37.97700 32.40900 80.91000  1.000 70.74000  ?  965  ALA AAZA C   1 
ATOM   3044 O O   . ALA A 1 423 ? 38.31600 31.31700 80.43900  1.000 70.96000  ?  965  ALA AAZA O   1 
ATOM   3045 C CB  . ALA A 1 423 ? 39.20100 33.19300 82.94500  1.000 69.49000  ?  965  ALA AAZA CB  1 
ATOM   3046 N N   . GLU A 1 424 ? 36.69100 32.80500 80.97500  1.000 71.06000  ?  966  GLU AAZA N   1 
ATOM   3047 C CA  . GLU A 1 424 ? 35.61200 31.92500 80.52600  1.000 70.85000  ?  966  GLU AAZA CA  1 
ATOM   3048 C C   . GLU A 1 424 ? 35.68500 31.67500 79.02100  1.000 75.48000  ?  966  GLU AAZA C   1 
ATOM   3049 O O   . GLU A 1 424 ? 35.46500 30.54400 78.55900  1.000 77.29000  ?  966  GLU AAZA O   1 
ATOM   3050 C CB  . GLU A 1 424 ? 34.25000 32.50300 80.91500  1.000 72.00000  ?  966  GLU AAZA CB  1 
ATOM   3051 C CG  . GLU A 1 424 ? 34.08400 32.77200 82.43100  1.000 85.88000  ?  966  GLU AAZA CG  1 
ATOM   3052 C CD  . GLU A 1 424 ? 32.65900 33.21200 82.86600  1.000 95.89000  ?  966  GLU AAZA CD  1 
ATOM   3053 O OE1 . GLU A 1 424 ? 31.69400 32.94100 82.10700  1.000 102.55000 ?  966  GLU AAZA OE1 1 
ATOM   3054 O OE2 . GLU A 1 424 ? 32.50900 33.81800 83.97200  1.000 91.48000  ?  966  GLU AAZA OE2 1 
ATOM   3055 N N   . ILE A 1 425 ? 36.01200 32.71200 78.24100  1.000 72.85000  ?  967  ILE AAZA N   1 
ATOM   3056 C CA  . ILE A 1 425 ? 36.18600 32.54800 76.79900  1.000 67.02000  ?  967  ILE AAZA CA  1 
ATOM   3057 C C   . ILE A 1 425 ? 37.36800 31.64300 76.50100  1.000 68.67000  ?  967  ILE AAZA C   1 
ATOM   3058 O O   . ILE A 1 425 ? 37.26800 30.73000 75.68300  1.000 74.82000  ?  967  ILE AAZA O   1 
ATOM   3059 C CB  . ILE A 1 425 ? 36.33800 33.91200 76.11400  1.000 62.72000  ?  967  ILE AAZA CB  1 
ATOM   3060 C CG1 . ILE A 1 425 ? 35.09000 34.76400 76.37000  1.000 60.28000  ?  967  ILE AAZA CG1 1 
ATOM   3061 C CG2 . ILE A 1 425 ? 36.68700 33.70900 74.64900  1.000 63.73000  ?  967  ILE AAZA CG2 1 
ATOM   3062 C CD1 . ILE A 1 425 ? 35.20200 36.19900 75.94900  1.000 60.17000  ?  967  ILE AAZA CD1 1 
ATOM   3063 N N   . THR A 1 426 ? 38.50900 31.88800 77.14100  1.000 66.88000  ?  968  THR AAZA N   1 
ATOM   3064 C CA  . THR A 1 426 ? 39.63200 30.96400 77.03100  1.000 68.46000  ?  968  THR AAZA CA  1 
ATOM   3065 C C   . THR A 1 426 ? 39.25200 29.53700 77.38800  1.000 75.63000  ?  968  THR AAZA C   1 
ATOM   3066 O O   . THR A 1 426 ? 39.60700 28.59100 76.67500  1.000 76.91000  ?  968  THR AAZA O   1 
ATOM   3067 C CB  . THR A 1 426 ? 40.76800 31.41300 77.92500  1.000 67.53000  ?  968  THR AAZA CB  1 
ATOM   3068 O OG1 . THR A 1 426 ? 41.37000 32.57800 77.37500  1.000 66.15000  ?  968  THR AAZA OG1 1 
ATOM   3069 C CG2 . THR A 1 426 ? 41.76300 30.30000 78.09200  1.000 77.80000  ?  968  THR AAZA CG2 1 
ATOM   3070 N N   . GLY A 1 427 ? 38.57900 29.35200 78.52000  1.000 74.28000  ?  969  GLY AAZA N   1 
ATOM   3071 C CA  . GLY A 1 427 ? 38.18000 28.01100 78.89300  1.000 74.65000  ?  969  GLY AAZA CA  1 
ATOM   3072 C C   . GLY A 1 427 ? 37.37000 27.34200 77.80300  1.000 74.50000  ?  969  GLY AAZA C   1 
ATOM   3073 O O   . GLY A 1 427 ? 37.61300 26.18000 77.45900  1.000 72.04000  ?  969  GLY AAZA O   1 
ATOM   3074 N N   . GLU A 1 428 ? 36.41700 28.08200 77.22600  1.000 72.63000  ?  970  GLU AAZA N   1 
ATOM   3075 C CA  . GLU A 1 428 ? 35.54900 27.52300 76.19900  1.000 74.57000  ?  970  GLU AAZA CA  1 
ATOM   3076 C C   . GLU A 1 428 ? 36.33300 27.06800 74.98100  1.000 74.73000  ?  970  GLU AAZA C   1 
ATOM   3077 O O   . GLU A 1 428 ? 35.98100 26.06500 74.35600  1.000 74.70000  ?  970  GLU AAZA O   1 
ATOM   3078 C CB  . GLU A 1 428 ? 34.50300 28.54900 75.80100  1.000 75.15000  ?  970  GLU AAZA CB  1 
ATOM   3079 C CG  . GLU A 1 428 ? 33.40600 27.93500 75.00600  1.000 83.29000  ?  970  GLU AAZA CG  1 
ATOM   3080 C CD  . GLU A 1 428 ? 32.47000 28.95200 74.42100  1.000 89.36000  ?  970  GLU AAZA CD  1 
ATOM   3081 O OE1 . GLU A 1 428 ? 31.92000 29.74500 75.23000  1.000 85.96000  ?  970  GLU AAZA OE1 1 
ATOM   3082 O OE2 . GLU A 1 428 ? 32.24800 28.91700 73.17600  1.000 91.03000  ?  970  GLU AAZA OE2 1 
ATOM   3083 N N   . ILE A 1 429 ? 37.41100 27.78300 74.64800  1.000 78.31000  ?  971  ILE AAZA N   1 
ATOM   3084 C CA  . ILE A 1 429 ? 38.27300 27.41300 73.52700  1.000 77.57000  ?  971  ILE AAZA CA  1 
ATOM   3085 C C   . ILE A 1 429 ? 38.92700 26.06900 73.77900  1.000 77.30000  ?  971  ILE AAZA C   1 
ATOM   3086 O O   . ILE A 1 429 ? 39.11700 25.27200 72.85900  1.000 80.25000  ?  971  ILE AAZA O   1 
ATOM   3087 C CB  . ILE A 1 429 ? 39.32200 28.51300 73.29300  1.000 75.09000  ?  971  ILE AAZA CB  1 
ATOM   3088 C CG1 . ILE A 1 429 ? 38.62800 29.85600 73.01400  1.000 75.02000  ?  971  ILE AAZA CG1 1 
ATOM   3089 C CG2 . ILE A 1 429 ? 40.26300 28.10800 72.18300  1.000 75.73000  ?  971  ILE AAZA CG2 1 
ATOM   3090 C CD1 . ILE A 1 429 ? 39.49500 30.91200 72.37300  1.000 72.94000  ?  971  ILE AAZA CD1 1 
ATOM   3091 N N   . GLN A 1 430 ? 39.27900 25.79600 75.03100  1.000 79.96000  ?  972  GLN AAZA N   1 
ATOM   3092 C CA  . GLN A 1 430 ? 39.94400 24.54900 75.36800  1.000 78.11000  ?  972  GLN AAZA CA  1 
ATOM   3093 C C   . GLN A 1 430 ? 39.00000 23.35100 75.32900  1.000 81.44000  ?  972  GLN AAZA C   1 
ATOM   3094 O O   . GLN A 1 430 ? 39.45000 22.23500 75.03500  1.000 83.31000  ?  972  GLN AAZA O   1 
ATOM   3095 C CB  . GLN A 1 430 ? 40.60500 24.70300 76.73400  1.000 76.33000  ?  972  GLN AAZA CB  1 
ATOM   3096 C CG  . GLN A 1 430 ? 41.65900 25.81900 76.72700  1.000 81.59000  ?  972  GLN AAZA CG  1 
ATOM   3097 C CD  . GLN A 1 430 ? 42.21100 26.17700 78.10100  1.000 79.18000  ?  972  GLN AAZA CD  1 
ATOM   3098 O OE1 . GLN A 1 430 ? 43.40900 26.03400 78.35000  1.000 82.15000  ?  972  GLN AAZA OE1 1 
ATOM   3099 N NE2 . GLN A 1 430 ? 41.33800 26.65200 78.99400  1.000 70.21000  ?  972  GLN AAZA NE2 1 
ATOM   3100 N N   . GLN A 1 431 ? 37.69600 23.54000 75.60000  1.000 79.78000  ?  973  GLN AAZA N   1 
ATOM   3101 C CA  . GLN A 1 431 ? 36.84400 22.35400 75.66800  1.000 80.12000  ?  973  GLN AAZA CA  1 
ATOM   3102 C C   . GLN A 1 431 ? 36.75800 21.68800 74.31800  1.000 82.93000  ?  973  GLN AAZA C   1 
ATOM   3103 O O   . GLN A 1 431 ? 36.50700 20.48400 74.24300  1.000 90.14000  ?  973  GLN AAZA O   1 
ATOM   3104 C CB  . GLN A 1 431 ? 35.41600 22.63400 76.16900  1.000 79.54000  ?  973  GLN AAZA CB  1 
ATOM   3105 C CG  . GLN A 1 431 ? 34.40900 23.11600 75.11100  1.000 89.48000  ?  973  GLN AAZA CG  1 
ATOM   3106 C CD  . GLN A 1 431 ? 32.91900 22.97700 75.54400  1.000 96.81000  ?  973  GLN AAZA CD  1 
ATOM   3107 O OE1 . GLN A 1 431 ? 32.22200 23.97600 75.80200  1.000 92.99000  ?  973  GLN AAZA OE1 1 
ATOM   3108 N NE2 . GLN A 1 431 ? 32.42700 21.72000 75.58300  1.000 92.69000  ?  973  GLN AAZA NE2 1 
ATOM   3109 N N   . TYR A 1 432 ? 36.99400 22.44400 73.25900  1.000 82.51000  ?  974  TYR AAZA N   1 
ATOM   3110 C CA  . TYR A 1 432 ? 36.96100 21.95700 71.89400  1.000 79.82000  ?  974  TYR AAZA CA  1 
ATOM   3111 C C   . TYR A 1 432 ? 38.33400 21.52600 71.39100  1.000 76.35000  ?  974  TYR AAZA C   1 
ATOM   3112 O O   . TYR A 1 432 ? 38.45700 21.11200 70.24200  1.000 76.63000  ?  974  TYR AAZA O   1 
ATOM   3113 C CB  . TYR A 1 432 ? 36.35600 23.04700 71.02300  1.000 78.78000  ?  974  TYR AAZA CB  1 
ATOM   3114 C CG  . TYR A 1 432 ? 34.87500 23.26800 71.30000  1.000 82.26000  ?  974  TYR AAZA CG  1 
ATOM   3115 C CD1 . TYR A 1 432 ? 33.98500 22.21100 71.23700  1.000 84.17000  ?  974  TYR AAZA CD1 1 
ATOM   3116 C CD2 . TYR A 1 432 ? 34.37000 24.52500 71.63400  1.000 81.16000  ?  974  TYR AAZA CD2 1 
ATOM   3117 C CE1 . TYR A 1 432 ? 32.63100 22.39400 71.47000  1.000 85.72000  ?  974  TYR AAZA CE1 1 
ATOM   3118 C CE2 . TYR A 1 432 ? 33.00700 24.71400 71.88100  1.000 82.28000  ?  974  TYR AAZA CE2 1 
ATOM   3119 C CZ  . TYR A 1 432 ? 32.14400 23.63800 71.79300  1.000 83.16000  ?  974  TYR AAZA CZ  1 
ATOM   3120 O OH  . TYR A 1 432 ? 30.78600 23.77700 72.01100  1.000 80.96000  ?  974  TYR AAZA OH  1 
ATOM   3121 N N   . GLN A 1 433 ? 39.34800 21.55800 72.24600  1.000 79.16000  ?  975  GLN AAZA N   1 
ATOM   3122 C CA  . GLN A 1 433 ? 40.72000 21.25000 71.87400  1.000 83.38000  ?  975  GLN AAZA CA  1 
ATOM   3123 C C   . GLN A 1 433 ? 41.16800 19.86200 72.31200  1.000 93.64000  ?  975  GLN AAZA C   1 
ATOM   3124 O O   . GLN A 1 433 ? 42.31100 19.47500 72.02500  1.000 88.40000  ?  975  GLN AAZA O   1 
ATOM   3125 C CB  . GLN A 1 433 ? 41.67800 22.27800 72.49500  1.000 78.73000  ?  975  GLN AAZA CB  1 
ATOM   3126 C CG  . GLN A 1 433 ? 41.90800 23.52300 71.68800  1.000 76.00000  ?  975  GLN AAZA CG  1 
ATOM   3127 C CD  . GLN A 1 433 ? 42.95200 24.40700 72.31600  1.000 78.22000  ?  975  GLN AAZA CD  1 
ATOM   3128 O OE1 . GLN A 1 433 ? 43.21900 24.29700 73.51100  1.000 82.79000  ?  975  GLN AAZA OE1 1 
ATOM   3129 N NE2 . GLN A 1 433 ? 43.54700 25.29900 71.51900  1.000 73.66000  ?  975  GLN AAZA NE2 1 
ATOM   3130 N N   . ASN A 1 434 ? 40.32200 19.12100 73.02800  1.000 97.42000  ?  976  ASN AAZA N   1 
ATOM   3131 C CA  . ASN A 1 434 ? 40.73400 17.87700 73.66900  1.000 97.27000  ?  976  ASN AAZA CA  1 
ATOM   3132 C C   . ASN A 1 434 ? 40.34300 16.64500 72.89000  1.000 100.98000 ?  976  ASN AAZA C   1 
ATOM   3133 O O   . ASN A 1 434 ? 41.11300 15.68200 72.83900  1.000 102.97000 ?  976  ASN AAZA O   1 
ATOM   3134 C CB  . ASN A 1 434 ? 40.14200 17.77300 75.06900  1.000 98.76000  ?  976  ASN AAZA CB  1 
ATOM   3135 C CG  . ASN A 1 434 ? 40.92200 18.56200 76.05800  1.000 106.98000 ?  976  ASN AAZA CG  1 
ATOM   3136 O OD1 . ASN A 1 434 ? 42.09200 18.25000 76.31800  1.000 111.22000 ?  976  ASN AAZA OD1 1 
ATOM   3137 N ND2 . ASN A 1 434 ? 40.30600 19.60900 76.61000  1.000 102.74000 ?  976  ASN AAZA ND2 1 
ATOM   3138 N N   . GLN A 1 435 ? 39.15900 16.64100 72.31000  1.000 98.76000  ?  977  GLN AAZA N   1 
ATOM   3139 C CA  . GLN A 1 435 ? 38.75500 15.51400 71.50800  1.000 101.66000 ?  977  GLN AAZA CA  1 
ATOM   3140 C C   . GLN A 1 435 ? 39.40500 15.60800 70.13500  1.000 100.20000 ?  977  GLN AAZA C   1 
ATOM   3141 O O   . GLN A 1 435 ? 39.12100 16.55400 69.39800  1.000 102.42000 ?  977  GLN AAZA O   1 
ATOM   3142 C CB  . GLN A 1 435 ? 37.24600 15.47200 71.37900  1.000 104.88000 ?  977  GLN AAZA CB  1 
ATOM   3143 C CG  . GLN A 1 435 ? 36.75600 14.08500 71.02600  1.000 110.53000 ?  977  GLN AAZA CG  1 
ATOM   3144 C CD  . GLN A 1 435 ? 37.50800 12.99900 71.79800  1.000 116.02000 ?  977  GLN AAZA CD  1 
ATOM   3145 O OE1 . GLN A 1 435 ? 37.66000 13.07500 73.03500  1.000 109.37000 ?  977  GLN AAZA OE1 1 
ATOM   3146 N NE2 . GLN A 1 435 ? 38.00000 11.98600 71.06300  1.000 111.40000 ?  977  GLN AAZA NE2 1 
ATOM   3147 N N   . PRO A 1 436 ? 40.29000 14.66500 69.75800  1.000 96.38000  ?  978  PRO AAZA N   1 
ATOM   3148 C CA  . PRO A 1 436 ? 40.85300 14.67800 68.40400  1.000 97.05000  ?  978  PRO AAZA CA  1 
ATOM   3149 C C   . PRO A 1 436 ? 39.97800 13.93600 67.39900  1.000 97.33000  ?  978  PRO AAZA C   1 
ATOM   3150 O O   . PRO A 1 436 ? 38.86900 13.50600 67.73600  1.000 100.17000 ?  978  PRO AAZA O   1 
ATOM   3151 C CB  . PRO A 1 436 ? 42.20800 13.99300 68.59000  1.000 90.83000  ?  978  PRO AAZA CB  1 
ATOM   3152 C CG  . PRO A 1 436 ? 42.00800 13.09000 69.69200  1.000 92.90000  ?  978  PRO AAZA CG  1 
ATOM   3153 C CD  . PRO A 1 436 ? 40.91300 13.62400 70.58200  1.000 98.94000  ?  978  PRO AAZA CD  1 
ATOM   3154 N N   . TYR A 1 437 ? 40.47100 13.76900 66.17300  1.000 89.34000  ?  979  TYR AAZA N   1 
ATOM   3155 C CA  . TYR A 1 437 ? 39.67100 13.31700 65.04100  1.000 96.11000  ?  979  TYR AAZA CA  1 
ATOM   3156 C C   . TYR A 1 437 ? 40.05700 11.89900 64.63100  1.000 103.46000 ?  979  TYR AAZA C   1 
ATOM   3157 O O   . TYR A 1 437 ? 41.24600 11.56000 64.58400  1.000 105.81000 ?  979  TYR AAZA O   1 
ATOM   3158 C CB  . TYR A 1 437 ? 39.85700 14.25100 63.84100  1.000 97.58000  ?  979  TYR AAZA CB  1 
ATOM   3159 C CG  . TYR A 1 437 ? 38.79100 15.31900 63.67100  1.000 92.42000  ?  979  TYR AAZA CG  1 
ATOM   3160 C CD1 . TYR A 1 437 ? 38.94800 16.57900 64.23300  1.000 89.47000  ?  979  TYR AAZA CD1 1 
ATOM   3161 C CD2 . TYR A 1 437 ? 37.66100 15.08200 62.91000  1.000 87.08000  ?  979  TYR AAZA CD2 1 
ATOM   3162 C CE1 . TYR A 1 437 ? 37.99800 17.55700 64.06700  1.000 87.43000  ?  979  TYR AAZA CE1 1 
ATOM   3163 C CE2 . TYR A 1 437 ? 36.70200 16.04900 62.74100  1.000 87.41000  ?  979  TYR AAZA CE2 1 
ATOM   3164 C CZ  . TYR A 1 437 ? 36.86900 17.28800 63.32200  1.000 91.27000  ?  979  TYR AAZA CZ  1 
ATOM   3165 O OH  . TYR A 1 437 ? 35.90200 18.26400 63.14800  1.000 91.01000  ?  979  TYR AAZA OH  1 
ATOM   3166 N N   . CYS A 1 438 ? 39.05300 11.08400 64.28300  1.000 102.10000 ?  980  CYS AAZA N   1 
ATOM   3167 C CA  . CYS A 1 438 ? 39.26800 9.67200  63.93800  1.000 102.76000 ?  980  CYS AAZA CA  1 
ATOM   3168 C C   . CYS A 1 438 ? 39.44000 9.53100  62.42000  1.000 108.66000 ?  980  CYS AAZA C   1 
ATOM   3169 O O   . CYS A 1 438 ? 38.59700 8.99200  61.69300  1.000 110.05000 ?  980  CYS AAZA O   1 
ATOM   3170 C CB  . CYS A 1 438 ? 38.11200 8.82900  64.47400  1.000 107.96000 ?  980  CYS AAZA CB  1 
ATOM   3171 S SG  . CYS A 1 438 ? 37.99000 7.10000  63.88900  1.000 122.52000 ?  980  CYS AAZA SG  1 
ATOM   3172 N N   . LEU A 1 439 ? 40.56500 10.05100 61.93500  1.000 102.94000 ?  981  LEU AAZA N   1 
ATOM   3173 C CA  . LEU A 1 439 ? 40.86900 10.02000 60.51100  1.000 98.14000  ?  981  LEU AAZA CA  1 
ATOM   3174 C C   . LEU A 1 439 ? 42.37100 9.87300  60.35600  1.000 100.11000 ?  981  LEU AAZA C   1 
ATOM   3175 O O   . LEU A 1 439 ? 43.13900 10.29800 61.22100  1.000 106.49000 ?  981  LEU AAZA O   1 
ATOM   3176 C CB  . LEU A 1 439 ? 40.39100 11.27900 59.77800  1.000 95.62000  ?  981  LEU AAZA CB  1 
ATOM   3177 C CG  . LEU A 1 439 ? 38.89800 11.64600 59.71100  1.000 98.95000  ?  981  LEU AAZA CG  1 
ATOM   3178 C CD1 . LEU A 1 439 ? 38.67800 12.91100 58.89300  1.000 89.82000  ?  981  LEU AAZA CD1 1 
ATOM   3179 C CD2 . LEU A 1 439 ? 38.01200 10.52800 59.17300  1.000 107.54000 ?  981  LEU AAZA CD2 1 
ATOM   3180 N N   . ARG A 1 440 ? 42.78800 9.27200  59.25200  1.000 97.24000  ?  982  ARG AAZA N   1 
ATOM   3181 C CA  . ARG A 1 440 ? 44.18000 8.89200  59.06600  1.000 98.31000  ?  982  ARG AAZA CA  1 
ATOM   3182 C C   . ARG A 1 440 ? 44.90600 9.93700  58.22400  1.000 93.98000  ?  982  ARG AAZA C   1 
ATOM   3183 O O   . ARG A 1 440 ? 44.34300 10.47900 57.27000  1.000 95.61000  ?  982  ARG AAZA O   1 
ATOM   3184 C CB  . ARG A 1 440 ? 44.24500 7.49000  58.43200  1.000 108.61000 ?  982  ARG AAZA CB  1 
ATOM   3185 C CG  . ARG A 1 440 ? 45.58700 7.06000  57.82500  1.000 112.46000 ?  982  ARG AAZA CG  1 
ATOM   3186 C CD  . ARG A 1 440 ? 45.70200 5.54300  57.67400  1.000 111.95000 ?  982  ARG AAZA CD  1 
ATOM   3187 N NE  . ARG A 1 440 ? 46.27100 4.95600  58.88300  1.000 119.93000 ?  982  ARG AAZA NE  1 
ATOM   3188 C CZ  . ARG A 1 440 ? 45.61600 4.15400  59.71100  1.000 125.59000 ?  982  ARG AAZA CZ  1 
ATOM   3189 N NH1 . ARG A 1 440 ? 44.37000 3.77600  59.46100  1.000 126.94000 ?  982  ARG AAZA NH1 1 
ATOM   3190 N NH2 . ARG A 1 440 ? 46.22400 3.72700  60.82000  1.000 119.63000 ?  982  ARG AAZA NH2 1 
ATOM   3191 N N   . VAL A 1 441 ? 46.15200 10.23200 58.58700  1.000 89.10000  ?  983  VAL AAZA N   1 
ATOM   3192 C CA  . VAL A 1 441 ? 46.93900 11.21200 57.84100  1.000 92.51000  ?  983  VAL AAZA CA  1 
ATOM   3193 C C   . VAL A 1 441 ? 47.42200 10.59800 56.53200  1.000 97.48000  ?  983  VAL AAZA C   1 
ATOM   3194 O O   . VAL A 1 441 ? 48.02300 9.51700  56.52200  1.000 103.16000 ?  983  VAL AAZA O   1 
ATOM   3195 C CB  . VAL A 1 441 ? 48.12900 11.71900 58.67400  1.000 90.93000  ?  983  VAL AAZA CB  1 
ATOM   3196 C CG1 . VAL A 1 441 ? 49.15400 12.41700 57.78800  1.000 90.57000  ?  983  VAL AAZA CG1 1 
ATOM   3197 C CG2 . VAL A 1 441 ? 47.66000 12.67300 59.73700  1.000 99.07000  ?  983  VAL AAZA CG2 1 
ATOM   3198 N N   . GLU A 1 442 ? 47.17400 11.29300 55.42400  1.000 95.17000  ?  984  GLU AAZA N   1 
ATOM   3199 C CA  . GLU A 1 442 ? 47.82100 10.98600 54.15000  1.000 98.12000  ?  984  GLU AAZA CA  1 
ATOM   3200 C C   . GLU A 1 442 ? 48.93500 12.02200 53.97400  1.000 98.26000  ?  984  GLU AAZA C   1 
ATOM   3201 O O   . GLU A 1 442 ? 48.71200 13.13100 53.49000  1.000 96.07000  ?  984  GLU AAZA O   1 
ATOM   3202 C CB  . GLU A 1 442 ? 46.80900 11.00300 53.00500  1.000 94.71000  ?  984  GLU AAZA CB  1 
ATOM   3203 C CG  . GLU A 1 442 ? 47.12500 10.01900 51.88500  1.000 97.19000  ?  984  GLU AAZA CG  1 
ATOM   3204 C CD  . GLU A 1 442 ? 48.38900 10.39000 51.13200  1.000 103.73000 ?  984  GLU AAZA CD  1 
ATOM   3205 O OE1 . GLU A 1 442 ? 48.69500 11.60000 51.08600  1.000 101.79000 ?  984  GLU AAZA OE1 1 
ATOM   3206 O OE2 . GLU A 1 442 ? 49.08000 9.48600  50.60100  1.000 104.98000 ?  984  GLU AAZA OE2 1 
ATOM   3207 N N   . SER A 1 443 ? 50.15400 11.65200 54.37200  1.000 98.41000  ?  985  SER AAZA N   1 
ATOM   3208 C CA  . SER A 1 443 ? 51.22000 12.64500 54.48100  1.000 100.59000 ?  985  SER AAZA CA  1 
ATOM   3209 C C   . SER A 1 443 ? 51.54200 13.30600 53.14500  1.000 100.18000 ?  985  SER AAZA C   1 
ATOM   3210 O O   . SER A 1 443 ? 52.03000 14.43900 53.13400  1.000 100.93000 ?  985  SER AAZA O   1 
ATOM   3211 C CB  . SER A 1 443 ? 52.47700 12.01400 55.09900  1.000 107.12000 ?  985  SER AAZA CB  1 
ATOM   3212 O OG  . SER A 1 443 ? 53.00600 10.97300 54.29200  1.000 119.66000 ?  985  SER AAZA OG  1 
ATOM   3213 N N   . ASP A 1 444 ? 51.27800 12.62900 52.01700  1.000 103.89000 ?  986  ASP AAZA N   1 
ATOM   3214 C CA  . ASP A 1 444 ? 51.50800 13.23000 50.69600  1.000 106.04000 ?  986  ASP AAZA CA  1 
ATOM   3215 C C   . ASP A 1 444 ? 50.58100 14.41200 50.44400  1.000 102.02000 ?  986  ASP AAZA C   1 
ATOM   3216 O O   . ASP A 1 444 ? 50.99400 15.43600 49.87800  1.000 96.06000  ?  986  ASP AAZA O   1 
ATOM   3217 C CB  . ASP A 1 444 ? 51.30400 12.19000 49.59300  1.000 107.08000 ?  986  ASP AAZA CB  1 
ATOM   3218 C CG  . ASP A 1 444 ? 52.59600 11.61500 49.08500  1.000 114.84000 ?  986  ASP AAZA CG  1 
ATOM   3219 O OD1 . ASP A 1 444 ? 53.65800 12.21500 49.37100  1.000 114.89000 ?  986  ASP AAZA OD1 1 
ATOM   3220 O OD2 . ASP A 1 444 ? 52.54200 10.56800 48.39500  1.000 118.04000 ?  986  ASP AAZA OD2 1 
ATOM   3221 N N   . ILE A 1 445 ? 49.31000 14.26300 50.81800  1.000 100.71000 ?  987  ILE AAZA N   1 
ATOM   3222 C CA  . ILE A 1 445 ? 48.32600 15.32400 50.65300  1.000 95.44000  ?  987  ILE AAZA CA  1 
ATOM   3223 C C   . ILE A 1 445 ? 48.56600 16.43900 51.65100  1.000 94.13000  ?  987  ILE AAZA C   1 
ATOM   3224 O O   . ILE A 1 445 ? 48.49900 17.62000 51.29400  1.000 95.09000  ?  987  ILE AAZA O   1 
ATOM   3225 C CB  . ILE A 1 445 ? 46.90800 14.76200 50.80800  1.000 92.85000  ?  987  ILE AAZA CB  1 
ATOM   3226 C CG1 . ILE A 1 445 ? 46.50900 13.93500 49.58100  1.000 91.06000  ?  987  ILE AAZA CG1 1 
ATOM   3227 C CG2 . ILE A 1 445 ? 45.96000 15.89700 51.10500  1.000 84.82000  ?  987  ILE AAZA CG2 1 
ATOM   3228 C CD1 . ILE A 1 445 ? 45.31600 13.03700 49.83300  1.000 87.49000  ?  987  ILE AAZA CD1 1 
ATOM   3229 N N   . LYS A 1 446 ? 48.80600 16.07600 52.92000  1.000 94.77000  ?  988  LYS AAZA N   1 
ATOM   3230 C CA  . LYS A 1 446 ? 49.14000 17.05800 53.94900  1.000 90.47000  ?  988  LYS AAZA CA  1 
ATOM   3231 C C   . LYS A 1 446 ? 50.26200 17.97700 53.49700  1.000 92.11000  ?  988  LYS AAZA C   1 
ATOM   3232 O O   . LYS A 1 446 ? 50.19200 19.19600 53.68800  1.000 91.74000  ?  988  LYS AAZA O   1 
ATOM   3233 C CB  . LYS A 1 446 ? 49.53200 16.35300 55.24100  1.000 93.09000  ?  988  LYS AAZA CB  1 
ATOM   3234 C CG  . LYS A 1 446 ? 49.75200 17.28200 56.41600  1.000 92.55000  ?  988  LYS AAZA CG  1 
ATOM   3235 C CD  . LYS A 1 446 ? 50.26800 16.50600 57.62900  1.000 92.57000  ?  988  LYS AAZA CD  1 
ATOM   3236 C CE  . LYS A 1 446 ? 50.82500 17.44400 58.68800  1.000 93.06000  ?  988  LYS AAZA CE  1 
ATOM   3237 N NZ  . LYS A 1 446 ? 51.40100 16.73200 59.85700  1.000 90.29000  ?  988  LYS AAZA NZ  1 
ATOM   3238 N N   . ARG A 1 447 ? 51.30400 17.41300 52.88300  1.000 96.81000  ?  989  ARG AAZA N   1 
ATOM   3239 C CA  . ARG A 1 447 ? 52.35900 18.24400 52.31600  1.000 92.43000  ?  989  ARG AAZA CA  1 
ATOM   3240 C C   . ARG A 1 447 ? 51.81900 19.13900 51.20900  1.000 87.10000  ?  989  ARG AAZA C   1 
ATOM   3241 O O   . ARG A 1 447 ? 52.26400 20.28100 51.06500  1.000 84.70000  ?  989  ARG AAZA O   1 
ATOM   3242 C CB  . ARG A 1 447 ? 53.49800 17.37500 51.78900  1.000 96.44000  ?  989  ARG AAZA CB  1 
ATOM   3243 C CG  . ARG A 1 447 ? 54.81000 18.11600 51.58100  1.000 100.67000 ?  989  ARG AAZA CG  1 
ATOM   3244 C CD  . ARG A 1 447 ? 55.89200 17.19000 51.03800  1.000 111.95000 ?  989  ARG AAZA CD  1 
ATOM   3245 N NE  . ARG A 1 447 ? 55.86900 15.87400 51.67100  1.000 120.32000 ?  989  ARG AAZA NE  1 
ATOM   3246 C CZ  . ARG A 1 447 ? 55.46200 14.76200 51.06800  1.000 120.01000 ?  989  ARG AAZA CZ  1 
ATOM   3247 N NH1 . ARG A 1 447 ? 55.06200 14.76600 49.80400  1.000 116.99000 ?  989  ARG AAZA NH1 1 
ATOM   3248 N NH2 . ARG A 1 447 ? 55.45300 13.61800 51.75100  1.000 118.64000 ?  989  ARG AAZA NH2 1 
ATOM   3249 N N   . PHE A 1 448 ? 50.86000 18.64800 50.41200  1.000 87.07000  ?  990  PHE AAZA N   1 
ATOM   3250 C CA  . PHE A 1 448 ? 50.36500 19.47500 49.31400  1.000 89.52000  ?  990  PHE AAZA CA  1 
ATOM   3251 C C   . PHE A 1 448 ? 49.65900 20.71100 49.83300  1.000 88.63000  ?  990  PHE AAZA C   1 
ATOM   3252 O O   . PHE A 1 448 ? 49.89600 21.82200 49.34100  1.000 89.01000  ?  990  PHE AAZA O   1 
ATOM   3253 C CB  . PHE A 1 448 ? 49.42100 18.71100 48.38800  1.000 89.17000  ?  990  PHE AAZA CB  1 
ATOM   3254 C CG  . PHE A 1 448 ? 48.82800 19.58400 47.30700  1.000 85.81000  ?  990  PHE AAZA CG  1 
ATOM   3255 C CD1 . PHE A 1 448 ? 49.64600 20.32800 46.47600  1.000 87.15000  ?  990  PHE AAZA CD1 1 
ATOM   3256 C CD2 . PHE A 1 448 ? 47.46200 19.68700 47.14100  1.000 87.46000  ?  990  PHE AAZA CD2 1 
ATOM   3257 C CE1 . PHE A 1 448 ? 49.10900 21.15800 45.48800  1.000 92.71000  ?  990  PHE AAZA CE1 1 
ATOM   3258 C CE2 . PHE A 1 448 ? 46.91900 20.50000 46.14300  1.000 87.78000  ?  990  PHE AAZA CE2 1 
ATOM   3259 C CZ  . PHE A 1 448 ? 47.74600 21.24100 45.31800  1.000 87.57000  ?  990  PHE AAZA CZ  1 
ATOM   3260 N N   . PHE A 1 449 ? 48.79200 20.54100 50.82700  1.000 91.85000  ?  991  PHE AAZA N   1 
ATOM   3261 C CA  . PHE A 1 449 ? 48.06900 21.68600 51.35800  1.000 90.20000  ?  991  PHE AAZA CA  1 
ATOM   3262 C C   . PHE A 1 449 ? 48.95100 22.55800 52.23100  1.000 86.00000  ?  991  PHE AAZA C   1 
ATOM   3263 O O   . PHE A 1 449 ? 48.82700 23.78400 52.17400  1.000 88.98000  ?  991  PHE AAZA O   1 
ATOM   3264 C CB  . PHE A 1 449 ? 46.82700 21.21700 52.10400  1.000 85.48000  ?  991  PHE AAZA CB  1 
ATOM   3265 C CG  . PHE A 1 449 ? 45.71100 20.89100 51.18100  1.000 87.69000  ?  991  PHE AAZA CG  1 
ATOM   3266 C CD1 . PHE A 1 449 ? 45.14100 21.88600 50.41200  1.000 84.15000  ?  991  PHE AAZA CD1 1 
ATOM   3267 C CD2 . PHE A 1 449 ? 45.26300 19.59100 51.03400  1.000 90.80000  ?  991  PHE AAZA CD2 1 
ATOM   3268 C CE1 . PHE A 1 449 ? 44.12200 21.60000 49.52800  1.000 87.25000  ?  991  PHE AAZA CE1 1 
ATOM   3269 C CE2 . PHE A 1 449 ? 44.23300 19.29400 50.15400  1.000 87.37000  ?  991  PHE AAZA CE2 1 
ATOM   3270 C CZ  . PHE A 1 449 ? 43.66500 20.30100 49.40000  1.000 87.60000  ?  991  PHE AAZA CZ  1 
ATOM   3271 N N   . GLU A 1 450 ? 49.86800 21.95600 52.99600  1.000 81.01000  ?  992  GLU AAZA N   1 
ATOM   3272 C CA  . GLU A 1 450 ? 50.85200 22.73400 53.74000  1.000 83.30000  ?  992  GLU AAZA CA  1 
ATOM   3273 C C   . GLU A 1 450 ? 51.61000 23.73200 52.85900  1.000 86.49000  ?  992  GLU AAZA C   1 
ATOM   3274 O O   . GLU A 1 450 ? 51.97000 24.81800 53.32400  1.000 87.62000  ?  992  GLU AAZA O   1 
ATOM   3275 C CB  . GLU A 1 450 ? 51.83100 21.79400 54.43500  1.000 89.44000  ?  992  GLU AAZA CB  1 
ATOM   3276 C CG  . GLU A 1 450 ? 51.36200 21.35400 55.82400  1.000 99.05000  ?  992  GLU AAZA CG  1 
ATOM   3277 C CD  . GLU A 1 450 ? 52.46200 20.72200 56.68200  1.000 102.92000 ?  992  GLU AAZA CD  1 
ATOM   3278 O OE1 . GLU A 1 450 ? 53.66300 20.79400 56.30500  1.000 106.27000 ?  992  GLU AAZA OE1 1 
ATOM   3279 O OE2 . GLU A 1 450 ? 52.10500 20.15000 57.73900  1.000 94.23000  ?  992  GLU AAZA OE2 1 
ATOM   3280 N N   . ASN A 1 451 ? 51.84100 23.40500 51.58600  1.000 88.47000  ?  993  ASN AAZA N   1 
ATOM   3281 C CA  . ASN A 1 451 ? 52.67300 24.23600 50.72400  1.000 84.25000  ?  993  ASN AAZA CA  1 
ATOM   3282 C C   . ASN A 1 451 ? 51.89600 25.24300 49.89800  1.000 80.44000  ?  993  ASN AAZA C   1 
ATOM   3283 O O   . ASN A 1 451 ? 52.52400 26.05500 49.21500  1.000 81.30000  ?  993  ASN AAZA O   1 
ATOM   3284 C CB  . ASN A 1 451 ? 53.48900 23.38000 49.75300  1.000 87.49000  ?  993  ASN AAZA CB  1 
ATOM   3285 C CG  . ASN A 1 451 ? 54.41700 22.43000 50.45800  1.000 89.70000  ?  993  ASN AAZA CG  1 
ATOM   3286 O OD1 . ASN A 1 451 ? 54.29500 22.22000 51.66700  1.000 90.95000  ?  993  ASN AAZA OD1 1 
ATOM   3287 N ND2 . ASN A 1 451 ? 55.37000 21.86400 49.71800  1.000 89.62000  ?  993  ASN AAZA ND2 1 
ATOM   3288 N N   . LEU A 1 452 ? 50.56800 25.20100 49.91200  1.000 80.31000  ?  994  LEU AAZA N   1 
ATOM   3289 C CA  . LEU A 1 452 ? 49.79100 26.11900 49.08800  1.000 81.46000  ?  994  LEU AAZA CA  1 
ATOM   3290 C C   . LEU A 1 452 ? 50.25600 27.55100 49.27500  1.000 76.91000  ?  994  LEU AAZA C   1 
ATOM   3291 O O   . LEU A 1 452 ? 50.12700 28.10800 50.36700  1.000 80.46000  ?  994  LEU AAZA O   1 
ATOM   3292 C CB  . LEU A 1 452 ? 48.31300 26.03800 49.43700  1.000 77.25000  ?  994  LEU AAZA CB  1 
ATOM   3293 C CG  . LEU A 1 452 ? 47.50200 24.90400 48.85100  1.000 76.25000  ?  994  LEU AAZA CG  1 
ATOM   3294 C CD1 . LEU A 1 452 ? 46.06700 25.18000 49.20600  1.000 75.47000  ?  994  LEU AAZA CD1 1 
ATOM   3295 C CD2 . LEU A 1 452 ? 47.70700 24.81600 47.35500  1.000 71.54000  ?  994  LEU AAZA CD2 1 
ATOM   3296 N N   . ASN A 1 453 ? 50.81200 28.16900 48.24600  1.000 68.32000  ?  995  ASN AAZA N   1 
ATOM   3297 C CA  . ASN A 1 453 ? 51.13200 29.58700 48.32600  1.000 75.15000  ?  995  ASN AAZA CA  1 
ATOM   3298 C C   . ASN A 1 453 ? 50.43200 30.30600 47.18200  1.000 77.93000  ?  995  ASN AAZA C   1 
ATOM   3299 O O   . ASN A 1 453 ? 51.08300 30.80900 46.25600  1.000 79.11000  ?  995  ASN AAZA O   1 
ATOM   3300 C CB  . ASN A 1 453 ? 52.63500 29.84700 48.31600  1.000 75.21000  ?  995  ASN AAZA CB  1 
ATOM   3301 C CG  . ASN A 1 453 ? 52.97400 31.28100 48.72000  1.000 88.30000  ?  995  ASN AAZA CG  1 
ATOM   3302 O OD1 . ASN A 1 453 ? 52.64100 31.73000 49.82700  1.000 94.23000  ?  995  ASN AAZA OD1 1 
ATOM   3303 N ND2 . ASN A 1 453 ? 53.63800 32.00600 47.82800  1.000 87.06000  ?  995  ASN AAZA ND2 1 
ATOM   3304 N N   . PRO A 1 454 ? 49.10200 30.39200 47.22900  1.000 75.60000  ?  996  PRO AAZA N   1 
ATOM   3305 C CA  . PRO A 1 454 ? 48.37800 31.03100 46.12500  1.000 74.77000  ?  996  PRO AAZA CA  1 
ATOM   3306 C C   . PRO A 1 454 ? 48.79500 32.46200 45.86900  1.000 78.56000  ?  996  PRO AAZA C   1 
ATOM   3307 O O   . PRO A 1 454 ? 48.70800 32.91500 44.72000  1.000 78.86000  ?  996  PRO AAZA O   1 
ATOM   3308 C CB  . PRO A 1 454 ? 46.91700 30.92900 46.57300  1.000 73.89000  ?  996  PRO AAZA CB  1 
ATOM   3309 C CG  . PRO A 1 454 ? 46.98400 30.80700 48.02700  1.000 70.14000  ?  996  PRO AAZA CG  1 
ATOM   3310 C CD  . PRO A 1 454 ? 48.19800 30.01900 48.32600  1.000 71.51000  ?  996  PRO AAZA CD  1 
ATOM   3311 N N   . MET A 1 455 ? 49.28200 33.17900 46.88400  1.000 78.30000  ?  997  MET AAZA N   1 
ATOM   3312 C CA  . MET A 1 455 ? 49.67900 34.56700 46.66600  1.000 77.56000  ?  997  MET AAZA CA  1 
ATOM   3313 C C   . MET A 1 455 ? 51.00500 34.69800 45.91700  1.000 78.89000  ?  997  MET AAZA C   1 
ATOM   3314 O O   . MET A 1 455 ? 51.35400 35.80900 45.50200  1.000 79.90000  ?  997  MET AAZA O   1 
ATOM   3315 C CB  . MET A 1 455 ? 49.74800 35.28800 48.01600  1.000 82.68000  ?  997  MET AAZA CB  1 
ATOM   3316 C CG  . MET A 1 455 ? 48.65000 36.32600 48.25100  1.000 80.37000  ?  997  MET AAZA CG  1 
ATOM   3317 S SD  . MET A 1 455 ? 48.74200 37.14900 49.87900  1.000 90.59000  ?  997  MET AAZA SD  1 
ATOM   3318 C CE  . MET A 1 455 ? 50.29400 38.03000 49.72300  1.000 86.63000  ?  997  MET AAZA CE  1 
ATOM   3319 N N   . GLY A 1 456 ? 51.74500 33.60700 45.73300  1.000 75.16000  ?  998  GLY AAZA N   1 
ATOM   3320 C CA  . GLY A 1 456 ? 53.02200 33.69900 45.04500  1.000 78.89000  ?  998  GLY AAZA CA  1 
ATOM   3321 C C   . GLY A 1 456 ? 54.02700 34.55300 45.80300  1.000 85.34000  ?  998  GLY AAZA C   1 
ATOM   3322 O O   . GLY A 1 456 ? 54.24200 34.39100 47.01100  1.000 88.66000  ?  998  GLY AAZA O   1 
ATOM   3323 N N   . ASN A 1 457 ? 54.68600 35.45800 45.08100  1.000 87.17000  ?  999  ASN AAZA N   1 
ATOM   3324 C CA  . ASN A 1 457 ? 55.54300 36.46800 45.68600  1.000 84.04000  ?  999  ASN AAZA CA  1 
ATOM   3325 C C   . ASN A 1 457 ? 54.87100 37.83000 45.68600  1.000 87.36000  ?  999  ASN AAZA C   1 
ATOM   3326 O O   . ASN A 1 457 ? 55.51900 38.83600 46.01200  1.000 86.17000  ?  999  ASN AAZA O   1 
ATOM   3327 C CB  . ASN A 1 457 ? 56.88000 36.55100 44.94900  1.000 88.10000  ?  999  ASN AAZA CB  1 
ATOM   3328 C CG  . ASN A 1 457 ? 57.67800 35.25400 45.02800  1.000 96.51000  ?  999  ASN AAZA CG  1 
ATOM   3329 O OD1 . ASN A 1 457 ? 57.64100 34.54100 46.04000  1.000 96.12000  ?  999  ASN AAZA OD1 1 
ATOM   3330 N ND2 . ASN A 1 457 ? 58.42000 34.95000 43.95900  1.000 99.80000  ?  999  ASN AAZA ND2 1 
ATOM   3331 N N   . SER A 1 458 ? 53.59000 37.87300 45.31000  1.000 83.15000  ?  1000 SER AAZA N   1 
ATOM   3332 C CA  . SER A 1 458 ? 52.84700 39.11200 45.17600  1.000 77.39000  ?  1000 SER AAZA CA  1 
ATOM   3333 C C   . SER A 1 458 ? 52.48000 39.63800 46.54900  1.000 80.57000  ?  1000 SER AAZA C   1 
ATOM   3334 O O   . SER A 1 458 ? 52.25700 38.87100 47.49300  1.000 81.19000  ?  1000 SER AAZA O   1 
ATOM   3335 C CB  . SER A 1 458 ? 51.56700 38.87800 44.37900  1.000 78.60000  ?  1000 SER AAZA CB  1 
ATOM   3336 O OG  . SER A 1 458 ? 51.82500 38.23900 43.14500  1.000 83.78000  ?  1000 SER AAZA OG  1 
ATOM   3337 N N   . MET A 1 459 ? 52.40600 40.95600 46.66900  1.000 78.56000  ?  1001 MET AAZA N   1 
ATOM   3338 C CA  . MET A 1 459 ? 51.82200 41.47100 47.89100  1.000 81.46000  ?  1001 MET AAZA CA  1 
ATOM   3339 C C   . MET A 1 459 ? 50.31200 41.23900 47.83200  1.000 79.70000  ?  1001 MET AAZA C   1 
ATOM   3340 O O   . MET A 1 459 ? 49.76600 40.76700 46.83700  1.000 78.16000  ?  1001 MET AAZA O   1 
ATOM   3341 C CB  . MET A 1 459 ? 52.18700 42.94500 48.09800  1.000 86.86000  ?  1001 MET AAZA CB  1 
ATOM   3342 C CG  . MET A 1 459 ? 53.69100 43.20800 48.14700  1.000 86.37000  ?  1001 MET AAZA CG  1 
ATOM   3343 S SD  . MET A 1 459 ? 54.57500 41.92600 49.05900  1.000 97.40000  ?  1001 MET AAZA SD  1 
ATOM   3344 C CE  . MET A 1 459 ? 56.30100 42.37400 48.79600  1.000 94.86000  ?  1001 MET AAZA CE  1 
ATOM   3345 N N   . GLU A 1 460 ? 49.62200 41.56400 48.91700  1.000 84.59000  ?  1002 GLU AAZA N   1 
ATOM   3346 C CA  . GLU A 1 460 ? 48.20500 41.23700 48.99400  1.000 81.00000  ?  1002 GLU AAZA CA  1 
ATOM   3347 C C   . GLU A 1 460 ? 47.37400 42.11800 48.05200  1.000 75.03000  ?  1002 GLU AAZA C   1 
ATOM   3348 O O   . GLU A 1 460 ? 46.41200 41.63600 47.45500  1.000 76.26000  ?  1002 GLU AAZA O   1 
ATOM   3349 C CB  . GLU A 1 460 ? 47.73200 41.37500 50.44200  1.000 86.39000  ?  1002 GLU AAZA CB  1 
ATOM   3350 C CG  . GLU A 1 460 ? 46.42000 40.68900 50.81000  1.000 81.72000  ?  1002 GLU AAZA CG  1 
ATOM   3351 C CD  . GLU A 1 460 ? 45.66600 41.43500 51.94200  1.000 92.91000  ?  1002 GLU AAZA CD  1 
ATOM   3352 O OE1 . GLU A 1 460 ? 46.29600 42.01700 52.87300  1.000 86.95000  ?  1002 GLU AAZA OE1 1 
ATOM   3353 O OE2 . GLU A 1 460 ? 44.41400 41.42200 51.89800  1.000 98.50000  ?  1002 GLU AAZA OE2 1 
ATOM   3354 N N   . LYS A 1 461 ? 47.69600 43.41400 47.92300  1.000 71.02000  ?  1003 LYS AAZA N   1 
ATOM   3355 C CA  . LYS A 1 461 ? 47.00300 44.23900 46.92600  1.000 73.53000  ?  1003 LYS AAZA CA  1 
ATOM   3356 C C   . LYS A 1 461 ? 47.12600 43.67800 45.52600  1.000 78.60000  ?  1003 LYS AAZA C   1 
ATOM   3357 O O   . LYS A 1 461 ? 46.11600 43.46600 44.84600  1.000 73.54000  ?  1003 LYS AAZA O   1 
ATOM   3358 C CB  . LYS A 1 461 ? 47.51400 45.67500 46.89500  1.000 83.47000  ?  1003 LYS AAZA CB  1 
ATOM   3359 C CG  . LYS A 1 461 ? 46.87000 46.61400 47.82900  1.000 97.47000  ?  1003 LYS AAZA CG  1 
ATOM   3360 C CD  . LYS A 1 461 ? 45.53200 46.94900 47.17000  1.000 103.58000 ?  1003 LYS AAZA CD  1 
ATOM   3361 C CE  . LYS A 1 461 ? 45.68500 47.55400 45.78900  1.000 82.38000  ?  1003 LYS AAZA CE  1 
ATOM   3362 N NZ  . LYS A 1 461 ? 46.50800 48.77900 45.75900  1.000 89.29000  ?  1003 LYS AAZA NZ  1 
ATOM   3363 N N   . GLU A 1 462 ? 48.36700 43.54200 45.04300  1.000 83.81000  ?  1004 GLU AAZA N   1 
ATOM   3364 C CA  . GLU A 1 462 ? 48.61300 43.02200 43.70700  1.000 80.72000  ?  1004 GLU AAZA CA  1 
ATOM   3365 C C   . GLU A 1 462 ? 47.76800 41.78600 43.44900  1.000 77.96000  ?  1004 GLU AAZA C   1 
ATOM   3366 O O   . GLU A 1 462 ? 47.10200 41.66300 42.41000  1.000 76.36000  ?  1004 GLU AAZA O   1 
ATOM   3367 C CB  . GLU A 1 462 ? 50.09700 42.70200 43.56700  1.000 80.68000  ?  1004 GLU AAZA CB  1 
ATOM   3368 C CG  . GLU A 1 462 ? 50.97700 43.88700 43.85500  1.000 95.99000  ?  1004 GLU AAZA CG  1 
ATOM   3369 C CD  . GLU A 1 462 ? 51.96900 44.13000 42.73200  1.000 126.33000 ?  1004 GLU AAZA CD  1 
ATOM   3370 O OE1 . GLU A 1 462 ? 52.21700 43.18200 41.94700  1.000 125.63000 ?  1004 GLU AAZA OE1 1 
ATOM   3371 O OE2 . GLU A 1 462 ? 52.49400 45.26700 42.63000  1.000 134.53000 ?  1004 GLU AAZA OE2 1 
ATOM   3372 N N   . PHE A 1 463 ? 47.75100 40.87800 44.41100  1.000 71.76000  ?  1005 PHE AAZA N   1 
ATOM   3373 C CA  . PHE A 1 463 ? 47.07200 39.62500 44.18800  1.000 64.75000  ?  1005 PHE AAZA CA  1 
ATOM   3374 C C   . PHE A 1 463 ? 45.57100 39.79200 44.27000  1.000 63.41000  ?  1005 PHE AAZA C   1 
ATOM   3375 O O   . PHE A 1 463 ? 44.84800 39.28600 43.42500  1.000 63.41000  ?  1005 PHE AAZA O   1 
ATOM   3376 C CB  . PHE A 1 463 ? 47.54300 38.59000 45.18400  1.000 65.90000  ?  1005 PHE AAZA CB  1 
ATOM   3377 C CG  . PHE A 1 463 ? 47.06600 37.24200 44.85600  1.000 65.39000  ?  1005 PHE AAZA CG  1 
ATOM   3378 C CD1 . PHE A 1 463 ? 47.66100 36.52500 43.85000  1.000 72.00000  ?  1005 PHE AAZA CD1 1 
ATOM   3379 C CD2 . PHE A 1 463 ? 45.96300 36.72000 45.48700  1.000 66.43000  ?  1005 PHE AAZA CD2 1 
ATOM   3380 C CE1 . PHE A 1 463 ? 47.20200 35.29000 43.51900  1.000 72.25000  ?  1005 PHE AAZA CE1 1 
ATOM   3381 C CE2 . PHE A 1 463 ? 45.50000 35.49200 45.17200  1.000 67.04000  ?  1005 PHE AAZA CE2 1 
ATOM   3382 C CZ  . PHE A 1 463 ? 46.11200 34.77300 44.18100  1.000 72.60000  ?  1005 PHE AAZA CZ  1 
ATOM   3383 N N   . THR A 1 464 ? 45.07200 40.46000 45.30300  1.000 73.64000  ?  1006 THR AAZA N   1 
ATOM   3384 C CA  . THR A 1 464 ? 43.63400 40.69800 45.37900  1.000 70.02000  ?  1006 THR AAZA CA  1 
ATOM   3385 C C   . THR A 1 464 ? 43.14100 41.36500 44.11400  1.000 68.92000  ?  1006 THR AAZA C   1 
ATOM   3386 O O   . THR A 1 464 ? 42.12700 40.95900 43.54100  1.000 65.52000  ?  1006 THR AAZA O   1 
ATOM   3387 C CB  . THR A 1 464 ? 43.28100 41.57200 46.57300  1.000 67.54000  ?  1006 THR AAZA CB  1 
ATOM   3388 O OG1 . THR A 1 464 ? 43.91800 41.06900 47.74400  1.000 68.50000  ?  1006 THR AAZA OG1 1 
ATOM   3389 C CG2 . THR A 1 464 ? 41.79600 41.56200 46.76800  1.000 83.24000  ?  1006 THR AAZA CG2 1 
ATOM   3390 N N   . ASP A 1 465 ? 43.85600 42.39800 43.66600  1.000 71.16000  ?  1007 ASP AAZA N   1 
ATOM   3391 C CA  . ASP A 1 465 ? 43.49100 43.09300 42.43900  1.000 69.46000  ?  1007 ASP AAZA CA  1 
ATOM   3392 C C   . ASP A 1 465 ? 43.46800 42.12900 41.26700  1.000 69.79000  ?  1007 ASP AAZA C   1 
ATOM   3393 O O   . ASP A 1 465 ? 42.48300 42.06800 40.52400  1.000 68.08000  ?  1007 ASP AAZA O   1 
ATOM   3394 C CB  . ASP A 1 465 ? 44.46600 44.24100 42.20300  1.000 74.98000  ?  1007 ASP AAZA CB  1 
ATOM   3395 C CG  . ASP A 1 465 ? 44.13300 45.47400 43.04400  1.000 84.86000  ?  1007 ASP AAZA CG  1 
ATOM   3396 O OD1 . ASP A 1 465 ? 43.09000 45.46800 43.74500  1.000 86.27000  ?  1007 ASP AAZA OD1 1 
ATOM   3397 O OD2 . ASP A 1 465 ? 44.94400 46.43000 43.04600  1.000 87.36000  ?  1007 ASP AAZA OD2 1 
ATOM   3398 N N   . TYR A 1 466 ? 44.52600 41.32300 41.12300  1.000 72.89000  ?  1008 TYR AAZA N   1 
ATOM   3399 C CA  . TYR A 1 466 ? 44.58000 40.32700 40.05500  1.000 67.58000  ?  1008 TYR AAZA CA  1 
ATOM   3400 C C   . TYR A 1 466 ? 43.35800 39.42300 40.07900  1.000 63.89000  ?  1008 TYR AAZA C   1 
ATOM   3401 O O   . TYR A 1 466 ? 42.69000 39.25200 39.06500  1.000 69.36000  ?  1008 TYR AAZA O   1 
ATOM   3402 C CB  . TYR A 1 466 ? 45.85000 39.49200 40.17400  1.000 66.70000  ?  1008 TYR AAZA CB  1 
ATOM   3403 C CG  . TYR A 1 466 ? 45.79700 38.24200 39.34300  1.000 69.24000  ?  1008 TYR AAZA CG  1 
ATOM   3404 C CD1 . TYR A 1 466 ? 46.04000 38.29000 37.96700  1.000 67.14000  ?  1008 TYR AAZA CD1 1 
ATOM   3405 C CD2 . TYR A 1 466 ? 45.51700 37.01200 39.91900  1.000 67.00000  ?  1008 TYR AAZA CD2 1 
ATOM   3406 C CE1 . TYR A 1 466 ? 45.99900 37.14500 37.18100  1.000 70.48000  ?  1008 TYR AAZA CE1 1 
ATOM   3407 C CE2 . TYR A 1 466 ? 45.47200 35.85500 39.13600  1.000 77.54000  ?  1008 TYR AAZA CE2 1 
ATOM   3408 C CZ  . TYR A 1 466 ? 45.70900 35.93000 37.76200  1.000 73.14000  ?  1008 TYR AAZA CZ  1 
ATOM   3409 O OH  . TYR A 1 466 ? 45.66600 34.79300 36.98400  1.000 65.80000  ?  1008 TYR AAZA OH  1 
ATOM   3410 N N   . LEU A 1 467 ? 43.04100 38.84400 41.23700  1.000 65.47000  ?  1009 LEU AAZA N   1 
ATOM   3411 C CA  . LEU A 1 467 ? 41.86800 37.98400 41.35100  1.000 64.70000  ?  1009 LEU AAZA CA  1 
ATOM   3412 C C   . LEU A 1 467 ? 40.59200 38.70600 40.92700  1.000 68.78000  ?  1009 LEU AAZA C   1 
ATOM   3413 O O   . LEU A 1 467 ? 39.66100 38.07500 40.41000  1.000 69.86000  ?  1009 LEU AAZA O   1 
ATOM   3414 C CB  . LEU A 1 467 ? 41.72400 37.46800 42.77600  1.000 52.96000  ?  1009 LEU AAZA CB  1 
ATOM   3415 C CG  . LEU A 1 467 ? 42.64200 36.35400 43.25800  1.000 55.79000  ?  1009 LEU AAZA CG  1 
ATOM   3416 C CD1 . LEU A 1 467 ? 42.02700 35.73400 44.48700  1.000 63.29000  ?  1009 LEU AAZA CD1 1 
ATOM   3417 C CD2 . LEU A 1 467 ? 42.89100 35.29200 42.23800  1.000 59.33000  ?  1009 LEU AAZA CD2 1 
ATOM   3418 N N   . PHE A 1 468 ? 40.52100 40.02000 41.11600  1.000 67.63000  ?  1010 PHE AAZA N   1 
ATOM   3419 C CA  . PHE A 1 468 ? 39.31700 40.70900 40.67300  1.000 66.89000  ?  1010 PHE AAZA CA  1 
ATOM   3420 C C   . PHE A 1 468 ? 39.33700 40.94900 39.17100  1.000 69.20000  ?  1010 PHE AAZA C   1 
ATOM   3421 O O   . PHE A 1 468 ? 38.34100 40.70200 38.48600  1.000 69.76000  ?  1010 PHE AAZA O   1 
ATOM   3422 C CB  . PHE A 1 468 ? 39.13500 42.01800 41.42600  1.000 63.82000  ?  1010 PHE AAZA CB  1 
ATOM   3423 C CG  . PHE A 1 468 ? 37.81800 42.66300 41.16100  1.000 66.19000  ?  1010 PHE AAZA CG  1 
ATOM   3424 C CD1 . PHE A 1 468 ? 36.69300 42.26800 41.85400  1.000 68.81000  ?  1010 PHE AAZA CD1 1 
ATOM   3425 C CD2 . PHE A 1 468 ? 37.70200 43.68200 40.24300  1.000 65.76000  ?  1010 PHE AAZA CD2 1 
ATOM   3426 C CE1 . PHE A 1 468 ? 35.47900 42.85700 41.60300  1.000 66.33000  ?  1010 PHE AAZA CE1 1 
ATOM   3427 C CE2 . PHE A 1 468 ? 36.49700 44.27900 40.00600  1.000 65.29000  ?  1010 PHE AAZA CE2 1 
ATOM   3428 C CZ  . PHE A 1 468 ? 35.38900 43.86900 40.68300  1.000 62.60000  ?  1010 PHE AAZA CZ  1 
ATOM   3429 N N   . ASN A 1 469 ? 40.46100 41.43100 38.64300  1.000 67.47000  ?  1011 ASN AAZA N   1 
ATOM   3430 C CA  . ASN A 1 469 ? 40.58700 41.59700 37.20600  1.000 65.04000  ?  1011 ASN AAZA CA  1 
ATOM   3431 C C   . ASN A 1 469 ? 40.25300 40.30800 36.47700  1.000 67.33000  ?  1011 ASN AAZA C   1 
ATOM   3432 O O   . ASN A 1 469 ? 39.58700 40.32500 35.44000  1.000 70.07000  ?  1011 ASN AAZA O   1 
ATOM   3433 C CB  . ASN A 1 469 ? 42.00100 42.05900 36.87300  1.000 64.36000  ?  1011 ASN AAZA CB  1 
ATOM   3434 C CG  . ASN A 1 469 ? 42.26800 43.46600 37.34100  1.000 67.09000  ?  1011 ASN AAZA CG  1 
ATOM   3435 O OD1 . ASN A 1 469 ? 41.34600 44.27500 37.45000  1.000 67.47000  ?  1011 ASN AAZA OD1 1 
ATOM   3436 N ND2 . ASN A 1 469 ? 43.53200 43.78700 37.57300  1.000 69.05000  ?  1011 ASN AAZA ND2 1 
ATOM   3437 N N   . LYS A 1 470 ? 40.67700 39.17600 37.02800  1.000 68.37000  ?  1012 LYS AAZA N   1 
ATOM   3438 C CA  . LYS A 1 470 ? 40.37400 37.88800 36.42200  1.000 69.83000  ?  1012 LYS AAZA CA  1 
ATOM   3439 C C   . LYS A 1 470 ? 38.87100 37.60800 36.40200  1.000 69.00000  ?  1012 LYS AAZA C   1 
ATOM   3440 O O   . LYS A 1 470 ? 38.32900 37.15600 35.39300  1.000 68.69000  ?  1012 LYS AAZA O   1 
ATOM   3441 C CB  . LYS A 1 470 ? 41.15700 36.78900 37.14600  1.000 67.02000  ?  1012 LYS AAZA CB  1 
ATOM   3442 C CG  . LYS A 1 470 ? 41.62000 35.69400 36.20000  1.000 77.14000  ?  1012 LYS AAZA CG  1 
ATOM   3443 C CD  . LYS A 1 470 ? 42.70600 36.15000 35.21900  1.000 74.50000  ?  1012 LYS AAZA CD  1 
ATOM   3444 C CE  . LYS A 1 470 ? 43.10100 35.00600 34.28400  1.000 71.83000  ?  1012 LYS AAZA CE  1 
ATOM   3445 N NZ  . LYS A 1 470 ? 44.53500 35.12200 33.88900  1.000 79.51000  ?  1012 LYS AAZA NZ  1 
ATOM   3446 N N   . SER A 1 471 ? 38.16900 37.88100 37.49200  1.000 71.61000  ?  1013 SER AAZA N   1 
ATOM   3447 C CA  . SER A 1 471 ? 36.71800 37.70900 37.43800  1.000 72.29000  ?  1013 SER AAZA CA  1 
ATOM   3448 C C   . SER A 1 471 ? 36.07500 38.68000 36.46200  1.000 68.25000  ?  1013 SER AAZA C   1 
ATOM   3449 O O   . SER A 1 471 ? 34.99200 38.41400 35.94500  1.000 69.31000  ?  1013 SER AAZA O   1 
ATOM   3450 C CB  . SER A 1 471 ? 36.08200 37.89000 38.82500  1.000 71.48000  ?  1013 SER AAZA CB  1 
ATOM   3451 O OG  . SER A 1 471 ? 34.70200 38.22900 38.70500  1.000 69.54000  ?  1013 SER AAZA OG  1 
ATOM   3452 N N   . LEU A 1 472 ? 36.69600 39.82600 36.23700  1.000 70.47000  ?  1014 LEU AAZA N   1 
ATOM   3453 C CA  . LEU A 1 472 ? 36.12500 40.77500 35.29700  1.000 74.19000  ?  1014 LEU AAZA CA  1 
ATOM   3454 C C   . LEU A 1 472 ? 36.22100 40.22200 33.88000  1.000 78.31000  ?  1014 LEU AAZA C   1 
ATOM   3455 O O   . LEU A 1 472 ? 35.24500 40.26300 33.11600  1.000 77.01000  ?  1014 LEU AAZA O   1 
ATOM   3456 C CB  . LEU A 1 472 ? 36.85500 42.11900 35.40000  1.000 71.12000  ?  1014 LEU AAZA CB  1 
ATOM   3457 C CG  . LEU A 1 472 ? 36.25800 43.09700 36.39800  1.000 65.98000  ?  1014 LEU AAZA CG  1 
ATOM   3458 C CD1 . LEU A 1 472 ? 37.02600 44.40000 36.37800  1.000 69.76000  ?  1014 LEU AAZA CD1 1 
ATOM   3459 C CD2 . LEU A 1 472 ? 34.76100 43.25900 36.24200  1.000 61.24000  ?  1014 LEU AAZA CD2 1 
ATOM   3460 N N   . GLU A 1 473 ? 37.38600 39.66000 33.52900  1.000 77.26000  ?  1015 GLU AAZA N   1 
ATOM   3461 C CA  . GLU A 1 473 ? 37.57900 39.18900 32.16900  1.000 74.62000  ?  1015 GLU AAZA CA  1 
ATOM   3462 C C   . GLU A 1 473 ? 36.62000 38.04300 31.85800  1.000 76.62000  ?  1015 GLU AAZA C   1 
ATOM   3463 O O   . GLU A 1 473 ? 35.93500 38.06700 30.83300  1.000 80.46000  ?  1015 GLU AAZA O   1 
ATOM   3464 C CB  . GLU A 1 473 ? 39.05600 38.82400 31.94400  1.000 75.76000  ?  1015 GLU AAZA CB  1 
ATOM   3465 C CG  . GLU A 1 473 ? 39.56500 37.46300 32.42000  1.000 80.66000  ?  1015 GLU AAZA CG  1 
ATOM   3466 C CD  . GLU A 1 473 ? 40.96500 37.05900 31.83100  1.000 92.33000  ?  1015 GLU AAZA CD  1 
ATOM   3467 O OE1 . GLU A 1 473 ? 41.42600 37.60000 30.76500  1.000 75.11000  ?  1015 GLU AAZA OE1 1 
ATOM   3468 O OE2 . GLU A 1 473 ? 41.58300 36.15000 32.44700  1.000 92.60000  ?  1015 GLU AAZA OE2 1 
ATOM   3469 N N   . ILE A 1 474 ? 36.45100 37.10200 32.78800  1.000 76.45000  ?  1016 ILE AAZA N   1 
ATOM   3470 C CA  . ILE A 1 474 ? 35.72100 35.87200 32.48600  1.000 75.81000  ?  1016 ILE AAZA CA  1 
ATOM   3471 C C   . ILE A 1 474 ? 34.20300 35.97300 32.59300  1.000 78.13000  ?  1016 ILE AAZA C   1 
ATOM   3472 O O   . ILE A 1 474 ? 33.52100 34.98300 32.29400  1.000 81.26000  ?  1016 ILE AAZA O   1 
ATOM   3473 C CB  . ILE A 1 474 ? 36.24800 34.73900 33.39000  1.000 78.03000  ?  1016 ILE AAZA CB  1 
ATOM   3474 C CG1 . ILE A 1 474 ? 35.88400 34.95700 34.86600  1.000 67.92000  ?  1016 ILE AAZA CG1 1 
ATOM   3475 C CG2 . ILE A 1 474 ? 37.74700 34.58500 33.18600  1.000 77.10000  ?  1016 ILE AAZA CG2 1 
ATOM   3476 C CD1 . ILE A 1 474 ? 36.44000 33.88500 35.74700  1.000 65.22000  ?  1016 ILE AAZA CD1 1 
ATOM   3477 N N   . GLU A 1 475 ? 33.64400 37.12200 33.00100  1.000 76.97000  ?  1017 GLU AAZA N   1 
ATOM   3478 C CA  . GLU A 1 475 ? 32.20100 37.38400 33.01400  1.000 78.17000  ?  1017 GLU AAZA CA  1 
ATOM   3479 C C   . GLU A 1 475 ? 31.99600 38.89700 32.99400  1.000 80.09000  ?  1017 GLU AAZA C   1 
ATOM   3480 O O   . GLU A 1 475 ? 31.89600 39.52200 34.05600  1.000 81.34000  ?  1017 GLU AAZA O   1 
ATOM   3481 C CB  . GLU A 1 475 ? 31.50000 36.78000 34.23900  1.000 68.25000  ?  1017 GLU AAZA CB  1 
ATOM   3482 C CG  . GLU A 1 475 ? 31.47000 35.27700 34.34300  1.000 70.24000  ?  1017 GLU AAZA CG  1 
ATOM   3483 C CD  . GLU A 1 475 ? 30.28900 34.74200 35.16300  1.000 79.32000  ?  1017 GLU AAZA CD  1 
ATOM   3484 O OE1 . GLU A 1 475 ? 29.26300 35.45400 35.30000  1.000 83.82000  ?  1017 GLU AAZA OE1 1 
ATOM   3485 O OE2 . GLU A 1 475 ? 30.38200 33.59800 35.67700  1.000 73.75000  ?  1017 GLU AAZA OE2 1 
ATOM   3486 N N   . PRO A 1 476 ? 31.96300 39.52900 31.83100  1.000 77.55000  ?  1018 PRO AAZA N   1 
ATOM   3487 C CA  . PRO A 1 476 ? 31.95600 40.99500 31.78100  1.000 76.83000  ?  1018 PRO AAZA CA  1 
ATOM   3488 C C   . PRO A 1 476 ? 30.61400 41.62100 32.16400  1.000 77.20000  ?  1018 PRO AAZA C   1 
ATOM   3489 O O   . PRO A 1 476 ? 29.58500 40.95300 32.26700  1.000 76.64000  ?  1018 PRO AAZA O   1 
ATOM   3490 C CB  . PRO A 1 476 ? 32.32700 41.27900 30.31500  1.000 81.31000  ?  1018 PRO AAZA CB  1 
ATOM   3491 C CG  . PRO A 1 476 ? 33.06900 40.05200 29.87000  1.000 75.14000  ?  1018 PRO AAZA CG  1 
ATOM   3492 C CD  . PRO A 1 476 ? 32.34900 38.93300 30.54100  1.000 76.91000  ?  1018 PRO AAZA CD  1 
ATOM   3493 N N   . ARG A 1 477 ? 30.65400 42.94800 32.35900  1.000 81.83000  ?  1019 ARG AAZA N   1 
ATOM   3494 C CA  . ARG A 1 477 ? 29.50700 43.76100 32.76300  1.000 90.54000  ?  1019 ARG AAZA CA  1 
ATOM   3495 C C   . ARG A 1 477 ? 28.37300 43.71200 31.74400  1.000 92.76000  ?  1019 ARG AAZA C   1 
ATOM   3496 O O   . ARG A 1 477 ? 28.54100 43.28100 30.61900  1.000 97.34000  ?  1019 ARG AAZA O   1 
ATOM   3497 C CB  . ARG A 1 477 ? 29.87800 45.23300 32.82700  1.000 101.42000 ?  1019 ARG AAZA CB  1 
ATOM   3498 C CG  . ARG A 1 477 ? 30.61200 45.67600 34.05800  1.000 99.30000  ?  1019 ARG AAZA CG  1 
ATOM   3499 C CD  . ARG A 1 477 ? 29.74500 46.50000 34.96000  1.000 101.57000 ?  1019 ARG AAZA CD  1 
ATOM   3500 N NE  . ARG A 1 477 ? 30.50700 46.91000 36.13600  1.000 120.98000 ?  1019 ARG AAZA NE  1 
ATOM   3501 C CZ  . ARG A 1 477 ? 30.73500 46.17800 37.22000  1.000 112.33000 ?  1019 ARG AAZA CZ  1 
ATOM   3502 N NH1 . ARG A 1 477 ? 30.24200 44.95600 37.34800  1.000 108.28000 ?  1019 ARG AAZA NH1 1 
ATOM   3503 N NH2 . ARG A 1 477 ? 31.50100 46.68000 38.18700  1.000 96.87000  ?  1019 ARG AAZA NH2 1 
ATOM   3504 N N   . ASN A 1 478 ? 27.21000 44.21900 32.13700  1.000 93.09000  ?  1020 ASN AAZA N   1 
ATOM   3505 C CA  . ASN A 1 478 ? 26.02300 44.04700 31.29900  1.000 94.75000  ?  1020 ASN AAZA CA  1 
ATOM   3506 C C   . ASN A 1 478 ? 26.18300 44.33900 29.82200  1.000 103.74000 ?  1020 ASN AAZA C   1 
ATOM   3507 O O   . ASN A 1 478 ? 25.70300 43.53300 29.00800  1.000 113.82000 ?  1020 ASN AAZA O   1 
ATOM   3508 C CB  . ASN A 1 478 ? 24.82800 44.88800 31.74900  1.000 105.70000 ?  1020 ASN AAZA CB  1 
ATOM   3509 C CG  . ASN A 1 478 ? 23.58500 44.64000 30.86500  1.000 104.80000 ?  1020 ASN AAZA CG  1 
ATOM   3510 O OD1 . ASN A 1 478 ? 22.76000 45.54300 30.65500  1.000 101.96000 ?  1020 ASN AAZA OD1 1 
ATOM   3511 N ND2 . ASN A 1 478 ? 23.45400 43.40900 30.34800  1.000 95.73000  ?  1020 ASN AAZA ND2 1 
ATOM   3512 N N   . PRO A 1 479 ? 26.72800 45.47100 29.40100  1.000 105.98000 ?  1021 PRO AAZA N   1 
ATOM   3513 C CA  . PRO A 1 479 ? 26.77900 45.72900 27.94700  1.000 95.99000  ?  1021 PRO AAZA CA  1 
ATOM   3514 C C   . PRO A 1 479 ? 27.56900 44.63100 27.23100  1.000 94.20000  ?  1021 PRO AAZA C   1 
ATOM   3515 O O   . PRO A 1 479 ? 26.96600 43.76600 26.58900  1.000 83.19000  ?  1021 PRO AAZA O   1 
ATOM   3516 C CB  . PRO A 1 479 ? 27.45700 47.10600 27.84900  1.000 95.08000  ?  1021 PRO AAZA CB  1 
ATOM   3517 C CG  . PRO A 1 479 ? 28.23500 47.24100 29.17500  1.000 108.77000 ?  1021 PRO AAZA CG  1 
ATOM   3518 C CD  . PRO A 1 479 ? 27.38000 46.53300 30.19800  1.000 100.20000 ?  1021 PRO AAZA CD  1 
ATOM   3519 N N   . LYS A 1 480 ? 28.90000 44.61700 27.40700  1.000 99.09000  ?  1022 LYS AAZA N   1 
ATOM   3520 C CA  . LYS A 1 480 ? 29.77400 43.71100 26.67200  1.000 88.19000  ?  1022 LYS AAZA CA  1 
ATOM   3521 C C   . LYS A 1 480 ? 29.39700 42.26400 26.96100  1.000 89.12000  ?  1022 LYS AAZA C   1 
ATOM   3522 O O   . LYS A 1 480 ? 29.13700 41.90200 28.11500  1.000 86.10000  ?  1022 LYS AAZA O   1 
ATOM   3523 C CB  . LYS A 1 480 ? 31.23900 43.95200 27.04200  1.000 80.55000  ?  1022 LYS AAZA CB  1 
ATOM   3524 C CG  . LYS A 1 480 ? 31.64000 45.41300 27.05500  1.000 82.01000  ?  1022 LYS AAZA CG  1 
ATOM   3525 C CD  . LYS A 1 480 ? 31.56300 46.01000 25.68500  1.000 90.65000  ?  1022 LYS AAZA CD  1 
ATOM   3526 C CE  . LYS A 1 480 ? 32.12200 47.42400 25.62100  1.000 93.04000  ?  1022 LYS AAZA CE  1 
ATOM   3527 N NZ  . LYS A 1 480 ? 32.01700 47.97000 24.21500  1.000 108.78000 ?  1022 LYS AAZA NZ  1 
ATOM   3528 N N   . PRO A 1 481 ? 29.35400 41.41100 25.94600  1.000 90.23000  ?  1023 PRO AAZA N   1 
ATOM   3529 C CA  . PRO A 1 481 ? 28.82300 40.06200 26.12700  1.000 88.27000  ?  1023 PRO AAZA CA  1 
ATOM   3530 C C   . PRO A 1 481 ? 29.89800 39.04500 26.47100  1.000 79.26000  ?  1023 PRO AAZA C   1 
ATOM   3531 O O   . PRO A 1 481 ? 31.09700 39.25400 26.27800  1.000 76.18000  ?  1023 PRO AAZA O   1 
ATOM   3532 C CB  . PRO A 1 481 ? 28.19900 39.75600 24.76000  1.000 82.22000  ?  1023 PRO AAZA CB  1 
ATOM   3533 C CG  . PRO A 1 481 ? 29.11300 40.47400 23.81600  1.000 84.67000  ?  1023 PRO AAZA CG  1 
ATOM   3534 C CD  . PRO A 1 481 ? 29.62000 41.71000 24.53000  1.000 84.10000  ?  1023 PRO AAZA CD  1 
ATOM   3535 N N   . LEU A 1 482 ? 29.42200 37.92300 26.95200  1.000 78.33000  ?  1024 LEU AAZA N   1 
ATOM   3536 C CA  . LEU A 1 482 ? 30.21300 36.87200 27.55500  1.000 76.38000  ?  1024 LEU AAZA CA  1 
ATOM   3537 C C   . LEU A 1 482 ? 31.06400 36.17900 26.51000  1.000 78.69000  ?  1024 LEU AAZA C   1 
ATOM   3538 O O   . LEU A 1 482 ? 30.52600 35.40700 25.71100  1.000 81.77000  ?  1024 LEU AAZA O   1 
ATOM   3539 C CB  . LEU A 1 482 ? 29.28500 35.86600 28.23000  1.000 71.81000  ?  1024 LEU AAZA CB  1 
ATOM   3540 C CG  . LEU A 1 482 ? 29.93000 34.64900 28.84700  1.000 73.49000  ?  1024 LEU AAZA CG  1 
ATOM   3541 C CD1 . LEU A 1 482 ? 30.70100 35.13300 30.04200  1.000 79.97000  ?  1024 LEU AAZA CD1 1 
ATOM   3542 C CD2 . LEU A 1 482 ? 28.86300 33.67600 29.26600  1.000 74.38000  ?  1024 LEU AAZA CD2 1 
ATOM   3543 N N   . PRO A 1 483 ? 32.37600 36.41200 26.47600  1.000 78.64000  ?  1025 PRO AAZA N   1 
ATOM   3544 C CA  . PRO A 1 483 ? 33.23800 35.63700 25.58100  1.000 81.32000  ?  1025 PRO AAZA CA  1 
ATOM   3545 C C   . PRO A 1 483 ? 33.36800 34.20200 26.06200  1.000 83.77000  ?  1025 PRO AAZA C   1 
ATOM   3546 O O   . PRO A 1 483 ? 33.02700 33.86000 27.19700  1.000 83.47000  ?  1025 PRO AAZA O   1 
ATOM   3547 C CB  . PRO A 1 483 ? 34.57500 36.37700 25.64600  1.000 77.99000  ?  1025 PRO AAZA CB  1 
ATOM   3548 C CG  . PRO A 1 483 ? 34.58500 37.01100 26.92600  1.000 72.97000  ?  1025 PRO AAZA CG  1 
ATOM   3549 C CD  . PRO A 1 483 ? 33.16400 37.32300 27.31700  1.000 75.49000  ?  1025 PRO AAZA CD  1 
ATOM   3550 N N   . ARG A 1 484 ? 33.85600 33.34500 25.16800  1.000 83.88000  ?  1026 ARG AAZA N   1 
ATOM   3551 C CA  . ARG A 1 484 ? 34.09200 31.94700 25.49600  1.000 83.44000  ?  1026 ARG AAZA CA  1 
ATOM   3552 C C   . ARG A 1 484 ? 35.59000 31.66500 25.47500  1.000 82.53000  ?  1026 ARG AAZA C   1 
ATOM   3553 O O   . ARG A 1 484 ? 36.32900 32.24300 24.67100  1.000 87.88000  ?  1026 ARG AAZA O   1 
ATOM   3554 C CB  . ARG A 1 484 ? 33.31400 31.02000 24.55500  1.000 89.24000  ?  1026 ARG AAZA CB  1 
ATOM   3555 C CG  . ARG A 1 484 ? 33.92400 30.64900 23.21600  1.000 101.05000 ?  1026 ARG AAZA CG  1 
ATOM   3556 C CD  . ARG A 1 484 ? 33.12100 29.46600 22.62800  1.000 107.89000 ?  1026 ARG AAZA CD  1 
ATOM   3557 N NE  . ARG A 1 484 ? 33.60100 29.03700 21.32000  1.000 124.08000 ?  1026 ARG AAZA NE  1 
ATOM   3558 C CZ  . ARG A 1 484 ? 33.15200 27.96900 20.67600  1.000 130.89000 ?  1026 ARG AAZA CZ  1 
ATOM   3559 N NH1 . ARG A 1 484 ? 32.23900 27.17500 21.21400  1.000 128.46000 ?  1026 ARG AAZA NH1 1 
ATOM   3560 N NH2 . ARG A 1 484 ? 33.61700 27.70200 19.45300  1.000 131.68000 ?  1026 ARG AAZA NH2 1 
ATOM   3561 N N   . PHE A 1 485 ? 36.03500 30.80600 26.39400  1.000 78.29000  ?  1027 PHE AAZA N   1 
ATOM   3562 C CA  . PHE A 1 485 ? 37.42900 30.66500 26.79000  1.000 74.76000  ?  1027 PHE AAZA CA  1 
ATOM   3563 C C   . PHE A 1 485 ? 37.86400 29.21000 26.66600  1.000 71.41000  ?  1027 PHE AAZA C   1 
ATOM   3564 O O   . PHE A 1 485 ? 37.05800 28.29700 26.87000  1.000 70.48000  ?  1027 PHE AAZA O   1 
ATOM   3565 C CB  . PHE A 1 485 ? 37.63000 31.15300 28.24600  1.000 71.82000  ?  1027 PHE AAZA CB  1 
ATOM   3566 C CG  . PHE A 1 485 ? 37.59800 32.66700 28.42400  1.000 71.11000  ?  1027 PHE AAZA CG  1 
ATOM   3567 C CD1 . PHE A 1 485 ? 38.71600 33.45000 28.14100  1.000 75.39000  ?  1027 PHE AAZA CD1 1 
ATOM   3568 C CD2 . PHE A 1 485 ? 36.45400 33.30900 28.86400  1.000 70.57000  ?  1027 PHE AAZA CD2 1 
ATOM   3569 C CE1 . PHE A 1 485 ? 38.69300 34.85300 28.30900  1.000 70.82000  ?  1027 PHE AAZA CE1 1 
ATOM   3570 C CE2 . PHE A 1 485 ? 36.42900 34.69200 29.01900  1.000 71.72000  ?  1027 PHE AAZA CE2 1 
ATOM   3571 C CZ  . PHE A 1 485 ? 37.55400 35.46000 28.74000  1.000 69.29000  ?  1027 PHE AAZA CZ  1 
ATOM   3572 N N   . PRO A 1 486 ? 39.13600 28.96400 26.34800  1.000 71.75000  ?  1028 PRO AAZA N   1 
ATOM   3573 C CA  . PRO A 1 486 ? 39.63000 27.58600 26.24600  1.000 75.07000  ?  1028 PRO AAZA CA  1 
ATOM   3574 C C   . PRO A 1 486 ? 39.53600 26.79300 27.54200  1.000 74.84000  ?  1028 PRO AAZA C   1 
ATOM   3575 O O   . PRO A 1 486 ? 39.53200 27.33800 28.64300  1.000 82.00000  ?  1028 PRO AAZA O   1 
ATOM   3576 C CB  . PRO A 1 486 ? 41.09200 27.77300 25.82200  1.000 78.93000  ?  1028 PRO AAZA CB  1 
ATOM   3577 C CG  . PRO A 1 486 ? 41.45100 29.12900 26.23000  1.000 75.44000  ?  1028 PRO AAZA CG  1 
ATOM   3578 C CD  . PRO A 1 486 ? 40.19300 29.93500 26.03400  1.000 75.65000  ?  1028 PRO AAZA CD  1 
ATOM   3579 N N   . LYS A 1 487 ? 39.44100 25.47500 27.39000  1.000 77.24000  ?  1029 LYS AAZA N   1 
ATOM   3580 C CA  . LYS A 1 487 ? 39.63200 24.56700 28.50600  1.000 76.65000  ?  1029 LYS AAZA CA  1 
ATOM   3581 C C   . LYS A 1 487 ? 41.10800 24.47400 28.84500  1.000 84.35000  ?  1029 LYS AAZA C   1 
ATOM   3582 O O   . LYS A 1 487 ? 41.97300 24.64600 27.97400  1.000 85.76000  ?  1029 LYS AAZA O   1 
ATOM   3583 C CB  . LYS A 1 487 ? 39.08200 23.18200 28.18500  1.000 74.25000  ?  1029 LYS AAZA CB  1 
ATOM   3584 C CG  . LYS A 1 487 ? 37.58200 23.11900 28.20800  1.000 75.26000  ?  1029 LYS AAZA CG  1 
ATOM   3585 C CD  . LYS A 1 487 ? 37.08000 21.79800 27.68700  1.000 77.33000  ?  1029 LYS AAZA CD  1 
ATOM   3586 C CE  . LYS A 1 487 ? 37.80400 20.58500 28.26600  1.000 82.50000  ?  1029 LYS AAZA CE  1 
ATOM   3587 N NZ  . LYS A 1 487 ? 37.05800 19.94400 29.38100  1.000 87.63000  ?  1029 LYS AAZA NZ  1 
ATOM   3588 N N   . LYS A 1 488 ? 41.38800 24.23900 30.13900  1.000 84.77000  ?  1030 LYS AAZA N   1 
ATOM   3589 C CA  . LYS A 1 488 ? 42.74200 24.05200 30.64700  1.000 87.22000  ?  1030 LYS AAZA CA  1 
ATOM   3590 C C   . LYS A 1 488 ? 42.91700 22.72800 31.35100  1.000 87.70000  ?  1030 LYS AAZA C   1 
ATOM   3591 O O   . LYS A 1 488 ? 44.03300 22.20100 31.40300  1.000 90.84000  ?  1030 LYS AAZA O   1 
ATOM   3592 C CB  . LYS A 1 488 ? 43.13000 25.17200 31.63000  1.000 90.99000  ?  1030 LYS AAZA CB  1 
ATOM   3593 C CG  . LYS A 1 488 ? 42.37900 25.19400 32.97900  1.000 92.62000  ?  1030 LYS AAZA CG  1 
ATOM   3594 C CD  . LYS A 1 488 ? 42.50400 26.57100 33.64100  1.000 91.11000  ?  1030 LYS AAZA CD  1 
ATOM   3595 C CE  . LYS A 1 488 ? 43.96000 26.97400 33.88900  1.000 94.06000  ?  1030 LYS AAZA CE  1 
ATOM   3596 N NZ  . LYS A 1 488 ? 44.18400 28.46900 33.86000  1.000 88.63000  ?  1030 LYS AAZA NZ  1 
ATOM   3597 N N   . TYR A 1 489 ? 41.84700 22.19700 31.91500  1.000 87.40000  ?  1031 TYR AAZA N   1 
ATOM   3598 C CA  . TYR A 1 489 ? 41.86600 20.87700 32.50800  1.000 91.90000  ?  1031 TYR AAZA CA  1 
ATOM   3599 C C   . TYR A 1 489 ? 41.71600 19.85600 31.39600  1.000 95.97000  ?  1031 TYR AAZA C   1 
ATOM   3600 O O   . TYR A 1 489 ? 40.88000 20.01500 30.50200  1.000 92.57000  ?  1031 TYR AAZA O   1 
ATOM   3601 C CB  . TYR A 1 489 ? 40.74900 20.75400 33.54400  1.000 93.06000  ?  1031 TYR AAZA CB  1 
ATOM   3602 C CG  . TYR A 1 489 ? 40.84400 21.79800 34.64500  1.000 89.51000  ?  1031 TYR AAZA CG  1 
ATOM   3603 C CD1 . TYR A 1 489 ? 42.03000 21.99100 35.33500  1.000 90.77000  ?  1031 TYR AAZA CD1 1 
ATOM   3604 C CD2 . TYR A 1 489 ? 39.78300 22.63900 34.92800  1.000 83.71000  ?  1031 TYR AAZA CD2 1 
ATOM   3605 C CE1 . TYR A 1 489 ? 42.14000 22.94200 36.32100  1.000 96.22000  ?  1031 TYR AAZA CE1 1 
ATOM   3606 C CE2 . TYR A 1 489 ? 39.88600 23.60300 35.90600  1.000 90.73000  ?  1031 TYR AAZA CE2 1 
ATOM   3607 C CZ  . TYR A 1 489 ? 41.06700 23.75400 36.60400  1.000 97.20000  ?  1031 TYR AAZA CZ  1 
ATOM   3608 O OH  . TYR A 1 489 ? 41.18000 24.71400 37.59300  1.000 100.62000 ?  1031 TYR AAZA OH  1 
ATOM   3609 N N   . SER A 1 490 ? 42.55600 18.82800 31.44000  1.000 102.32000 ?  1032 SER AAZA N   1 
ATOM   3610 C CA  . SER A 1 490 ? 42.62700 17.81200 30.40400  1.000 96.45000  ?  1032 SER AAZA CA  1 
ATOM   3611 C C   . SER A 1 490 ? 41.93700 16.51700 30.80300  1.000 95.84000  ?  1032 SER AAZA C   1 
ATOM   3612 O O   . SER A 1 490 ? 41.69200 15.67500 29.93200  1.000 101.23000 ?  1032 SER AAZA O   1 
ATOM   3613 C CB  . SER A 1 490 ? 44.09100 17.53400 30.07700  1.000 93.76000  ?  1032 SER AAZA CB  1 
ATOM   3614 O OG  . SER A 1 490 ? 44.74600 18.75800 29.79000  1.000 99.01000  ?  1032 SER AAZA OG  1 
ATOM   3615 N N   . TYR A 1 491 ? 41.62800 16.34500 32.10200  1.000 95.31000  ?  1033 TYR AAZA N   1 
ATOM   3616 C CA  . TYR A 1 491 ? 40.94500 15.20900 32.71000  1.000 90.56000  ?  1033 TYR AAZA CA  1 
ATOM   3617 C C   . TYR A 1 491 ? 39.43500 15.42200 32.66600  1.000 89.81000  ?  1033 TYR AAZA C   1 
ATOM   3618 O O   . TYR A 1 491 ? 38.98100 16.48800 32.23400  1.000 94.12000  ?  1033 TYR AAZA O   1 
ATOM   3619 C CB  . TYR A 1 491 ? 41.42200 15.00700 34.15500  1.000 93.93000  ?  1033 TYR AAZA CB  1 
ATOM   3620 C CG  . TYR A 1 491 ? 41.81500 16.26600 34.91300  1.000 94.58000  ?  1033 TYR AAZA CG  1 
ATOM   3621 C CD1 . TYR A 1 491 ? 40.88200 16.99300 35.63800  1.000 91.73000  ?  1033 TYR AAZA CD1 1 
ATOM   3622 C CD2 . TYR A 1 491 ? 43.12600 16.71400 34.91200  1.000 95.37000  ?  1033 TYR AAZA CD2 1 
ATOM   3623 C CE1 . TYR A 1 491 ? 41.24700 18.13500 36.33300  1.000 91.57000  ?  1033 TYR AAZA CE1 1 
ATOM   3624 C CE2 . TYR A 1 491 ? 43.49900 17.84600 35.60900  1.000 95.69000  ?  1033 TYR AAZA CE2 1 
ATOM   3625 C CZ  . TYR A 1 491 ? 42.56100 18.56000 36.31500  1.000 96.08000  ?  1033 TYR AAZA CZ  1 
ATOM   3626 O OH  . TYR A 1 491 ? 42.96400 19.69500 37.00100  1.000 96.22000  ?  1033 TYR AAZA OH  1 
ATOM   3627 N N   . PRO A 1 492 ? 38.62600 14.43600 33.06300  1.000 88.25000  ?  1034 PRO AAZA N   1 
ATOM   3628 C CA  . PRO A 1 492 ? 37.17200 14.63700 33.11600  1.000 94.40000  ?  1034 PRO AAZA CA  1 
ATOM   3629 C C   . PRO A 1 492 ? 36.65100 15.25400 34.41200  1.000 103.16000 ?  1034 PRO AAZA C   1 
ATOM   3630 O O   . PRO A 1 492 ? 37.12500 14.98000 35.52300  1.000 100.33000 ?  1034 PRO AAZA O   1 
ATOM   3631 C CB  . PRO A 1 492 ? 36.64100 13.21000 32.94200  1.000 90.31000  ?  1034 PRO AAZA CB  1 
ATOM   3632 C CG  . PRO A 1 492 ? 37.67800 12.38000 33.58200  1.000 89.89000  ?  1034 PRO AAZA CG  1 
ATOM   3633 C CD  . PRO A 1 492 ? 38.96500 13.00600 33.15000  1.000 89.92000  ?  1034 PRO AAZA CD  1 
ATOM   3634 N N   . LEU A 1 493 ? 35.61800 16.08500 34.25100  1.000 100.28000 ?  1035 LEU AAZA N   1 
ATOM   3635 C CA  . LEU A 1 493 ? 35.11700 16.93100 35.33100  1.000 96.14000  ?  1035 LEU AAZA CA  1 
ATOM   3636 C C   . LEU A 1 493 ? 33.77700 16.40200 35.82900  1.000 101.93000 ?  1035 LEU AAZA C   1 
ATOM   3637 O O   . LEU A 1 493 ? 32.71500 16.98600 35.62300  1.000 110.81000 ?  1035 LEU AAZA O   1 
ATOM   3638 C CB  . LEU A 1 493 ? 35.00500 18.37200 34.85300  1.000 95.78000  ?  1035 LEU AAZA CB  1 
ATOM   3639 C CG  . LEU A 1 493 ? 36.20200 18.87300 34.04400  1.000 97.71000  ?  1035 LEU AAZA CG  1 
ATOM   3640 C CD1 . LEU A 1 493 ? 35.99100 20.31700 33.60900  1.000 89.36000  ?  1035 LEU AAZA CD1 1 
ATOM   3641 C CD2 . LEU A 1 493 ? 37.51100 18.71000 34.83600  1.000 93.81000  ?  1035 LEU AAZA CD2 1 
ATOM   3642 N N   . LYS A 1 494 ? 33.84600 15.25600 36.49300  1.000 99.40000  ?  1036 LYS AAZA N   1 
ATOM   3643 C CA  . LYS A 1 494 ? 32.67700 14.65700 37.11700  1.000 99.17000  ?  1036 LYS AAZA CA  1 
ATOM   3644 C C   . LYS A 1 494 ? 33.05200 14.35200 38.55500  1.000 100.58000 ?  1036 LYS AAZA C   1 
ATOM   3645 O O   . LYS A 1 494 ? 34.08500 13.71700 38.81000  1.000 100.51000 ?  1036 LYS AAZA O   1 
ATOM   3646 C CB  . LYS A 1 494 ? 32.23500 13.39100 36.37800  1.000 96.44000  ?  1036 LYS AAZA CB  1 
ATOM   3647 C CG  . LYS A 1 494 ? 30.88300 12.88600 36.82500  1.000 102.73000 ?  1036 LYS AAZA CG  1 
ATOM   3648 C CD  . LYS A 1 494 ? 30.77000 11.37600 36.68200  1.000 101.30000 ?  1036 LYS AAZA CD  1 
ATOM   3649 C CE  . LYS A 1 494 ? 29.54300 10.85500 37.42500  1.000 112.43000 ?  1036 LYS AAZA CE  1 
ATOM   3650 N NZ  . LYS A 1 494 ? 28.32900 11.71100 37.17400  1.000 118.64000 ?  1036 LYS AAZA NZ  1 
ATOM   3651 N N   . SER A 1 495 ? 32.22500 14.79600 39.49900  1.000 94.65000  ?  1037 SER AAZA N   1 
ATOM   3652 C CA  . SER A 1 495 ? 32.58400 14.62000 40.92700  1.000 95.10000  ?  1037 SER AAZA CA  1 
ATOM   3653 C C   . SER A 1 495 ? 32.47300 13.15000 41.31400  1.000 94.58000  ?  1037 SER AAZA C   1 
ATOM   3654 O O   . SER A 1 495 ? 31.41700 12.55400 41.06500  1.000 102.59000 ?  1037 SER AAZA O   1 
ATOM   3655 C CB  . SER A 1 495 ? 31.71200 15.45900 41.80700  1.000 99.43000  ?  1037 SER AAZA CB  1 
ATOM   3656 O OG  . SER A 1 495 ? 30.38200 14.96800 41.80600  1.000 105.00000 ?  1037 SER AAZA OG  1 
ATOM   3657 N N   . PRO A 1 496 ? 33.49900 12.55400 41.94400  1.000 87.61000  ?  1038 PRO AAZA N   1 
ATOM   3658 C CA  . PRO A 1 496 ? 33.40500 11.17600 42.39800  1.000 91.16000  ?  1038 PRO AAZA CA  1 
ATOM   3659 C C   . PRO A 1 496 ? 32.29600 11.04800 43.44600  1.000 91.69000  ?  1038 PRO AAZA C   1 
ATOM   3660 O O   . PRO A 1 496 ? 31.92800 9.94100  43.76900  1.000 94.70000  ?  1038 PRO AAZA O   1 
ATOM   3661 C CB  . PRO A 1 496 ? 34.76900 10.91900 43.04300  1.000 91.14000  ?  1038 PRO AAZA CB  1 
ATOM   3662 C CG  . PRO A 1 496 ? 35.29800 12.29200 43.37000  1.000 94.78000  ?  1038 PRO AAZA CG  1 
ATOM   3663 C CD  . PRO A 1 496 ? 34.78200 13.17500 42.25500  1.000 91.35000  ?  1038 PRO AAZA CD  1 
ATOM   3664 N N   . GLY A 1 497 ? 31.80300 12.17900 43.94800  1.000 94.52000  ?  1039 GLY AAZA N   1 
ATOM   3665 C CA  . GLY A 1 497 ? 30.72600 12.15900 44.95400  1.000 95.62000  ?  1039 GLY AAZA CA  1 
ATOM   3666 C C   . GLY A 1 497 ? 31.28000 12.26900 46.35900  1.000 96.87000  ?  1039 GLY AAZA C   1 
ATOM   3667 O O   . GLY A 1 497 ? 32.51200 12.27200 46.50000  1.000 91.98000  ?  1039 GLY AAZA O   1 
ATOM   3668 N N   . VAL A 1 498 ? 30.40500 12.34700 47.36500  1.000 102.49000 ?  1040 VAL AAZA N   1 
ATOM   3669 C CA  . VAL A 1 498 ? 30.87900 12.53000 48.73400  1.000 97.09000  ?  1040 VAL AAZA CA  1 
ATOM   3670 C C   . VAL A 1 498 ? 30.33200 11.45900 49.67900  1.000 102.56000 ?  1040 VAL AAZA C   1 
ATOM   3671 O O   . VAL A 1 498 ? 29.84100 11.77900 50.77000  1.000 99.30000  ?  1040 VAL AAZA O   1 
ATOM   3672 C CB  . VAL A 1 498 ? 30.50300 13.93600 49.23100  1.000 93.22000  ?  1040 VAL AAZA CB  1 
ATOM   3673 C CG1 . VAL A 1 498 ? 31.49100 14.95500 48.70800  1.000 88.12000  ?  1040 VAL AAZA CG1 1 
ATOM   3674 C CG2 . VAL A 1 498 ? 29.08400 14.28800 48.77900  1.000 97.41000  ?  1040 VAL AAZA CG2 1 
ATOM   3675 N N   . ARG A 1 499 ? 30.43000 10.18600 49.28200  1.000 105.72000 ?  1041 ARG AAZA N   1 
ATOM   3676 C CA  . ARG A 1 499 ? 30.08400 9.04800  50.12200  1.000 107.31000 ?  1041 ARG AAZA CA  1 
ATOM   3677 C C   . ARG A 1 499 ? 31.23900 8.05800  50.16800  1.000 109.70000 ?  1041 ARG AAZA C   1 
ATOM   3678 O O   . ARG A 1 499 ? 31.98400 7.93600  49.19400  1.000 115.63000 ?  1041 ARG AAZA O   1 
ATOM   3679 C CB  . ARG A 1 499 ? 28.82500 8.35100  49.60400  1.000 105.39000 ?  1041 ARG AAZA CB  1 
ATOM   3680 C CG  . ARG A 1 499 ? 27.64000 9.28300  49.48200  1.000 110.01000 ?  1041 ARG AAZA CG  1 
ATOM   3681 C CD  . ARG A 1 499 ? 26.41300 8.55200  48.96100  1.000 124.56000 ?  1041 ARG AAZA CD  1 
ATOM   3682 N NE  . ARG A 1 499 ? 26.62300 8.01600  47.61700  1.000 141.86000 ?  1041 ARG AAZA NE  1 
ATOM   3683 C CZ  . ARG A 1 499 ? 25.99700 8.43600  46.52300  1.000 143.86000 ?  1041 ARG AAZA CZ  1 
ATOM   3684 N NH1 . ARG A 1 499 ? 25.07700 9.39000  46.57400  1.000 144.95000 ?  1041 ARG AAZA NH1 1 
ATOM   3685 N NH2 . ARG A 1 499 ? 26.30000 7.88500  45.34600  1.000 130.50000 ?  1041 ARG AAZA NH2 1 
ATOM   3686 N N   . PRO A 1 500 ? 31.49100 7.37200  51.30100  1.000 106.96000 ?  1042 PRO AAZA N   1 
ATOM   3687 C CA  . PRO A 1 500 ? 32.69300 6.53800  51.41500  1.000 118.24000 ?  1042 PRO AAZA CA  1 
ATOM   3688 C C   . PRO A 1 500 ? 32.65200 5.15200  50.75900  1.000 124.74000 ?  1042 PRO AAZA C   1 
ATOM   3689 O O   . PRO A 1 500 ? 31.86200 4.95600  49.86100  1.000 125.95000 ?  1042 PRO AAZA O   1 
ATOM   3690 C CB  . PRO A 1 500 ? 32.78800 6.35400  52.93400  1.000 127.34000 ?  1042 PRO AAZA CB  1 
ATOM   3691 C CG  . PRO A 1 500 ? 31.34800 6.31200  53.38200  1.000 121.63000 ?  1042 PRO AAZA CG  1 
ATOM   3692 C CD  . PRO A 1 500 ? 30.65800 7.33600  52.50900  1.000 110.21000 ?  1042 PRO AAZA CD  1 
ATOM   3693 N N   . SER A 1 501 ? 33.51500 4.24300  51.22300  1.000 126.38000 ?  1043 SER AAZA N   1 
ATOM   3694 C CA  . SER A 1 501 ? 33.58700 2.87500  50.64700  1.000 130.92000 ?  1043 SER AAZA CA  1 
ATOM   3695 C C   . SER A 1 501 ? 33.55400 2.96300  49.11900  1.000 140.28000 ?  1043 SER AAZA C   1 
ATOM   3696 O O   . SER A 1 501 ? 34.25900 3.84000  48.59000  1.000 139.77000 ?  1043 SER AAZA O   1 
ATOM   3697 C CB  . SER A 1 501 ? 32.48300 1.99900  51.17900  1.000 130.92000 ?  1043 SER AAZA CB  1 
ATOM   3698 O OG  . SER A 1 501 ? 32.63000 1.79000  52.57500  1.000 132.98000 ?  1043 SER AAZA OG  1 
ATOM   3699 N N   . VAL B 2 2   ? 6.56600  41.10600 50.45500  1.000 145.01000 ?  2    VAL C    N   1 
ATOM   3700 C CA  . VAL B 2 2   ? 6.63900  42.45300 49.81200  1.000 142.29000 ?  2    VAL C    CA  1 
ATOM   3701 C C   . VAL B 2 2   ? 5.33700  42.70400 49.05000  1.000 139.34000 ?  2    VAL C    C   1 
ATOM   3702 O O   . VAL B 2 2   ? 4.54900  41.75300 48.89600  1.000 130.85000 ?  2    VAL C    O   1 
ATOM   3703 C CB  . VAL B 2 2   ? 7.86200  42.59400 48.88400  1.000 137.49000 ?  2    VAL C    CB  1 
ATOM   3704 C CG1 . VAL B 2 2   ? 9.09500  41.90700 49.44900  1.000 130.82000 ?  2    VAL C    CG1 1 
ATOM   3705 C CG2 . VAL B 2 2   ? 7.57000  42.12000 47.46900  1.000 130.78000 ?  2    VAL C    CG2 1 
ATOM   3706 N N   . GLN B 2 3   ? 5.13400  43.93700 48.58600  1.000 138.32000 ?  3    GLN C    N   1 
ATOM   3707 C CA  . GLN B 2 3   ? 3.85700  44.27200 47.90900  1.000 139.64000 ?  3    GLN C    CA  1 
ATOM   3708 C C   . GLN B 2 3   ? 4.13100  44.87100 46.53000  1.000 139.50000 ?  3    GLN C    C   1 
ATOM   3709 O O   . GLN B 2 3   ? 4.78000  45.92900 46.47000  1.000 144.05000 ?  3    GLN C    O   1 
ATOM   3710 C CB  . GLN B 2 3   ? 3.05400  45.25900 48.75600  1.000 141.74000 ?  3    GLN C    CB  1 
ATOM   3711 C CG  . GLN B 2 3   ? 1.68500  45.57700 48.17500  1.000 145.84000 ?  3    GLN C    CG  1 
ATOM   3712 C CD  . GLN B 2 3   ? 0.95700  44.32900 47.73900  1.000 143.07000 ?  3    GLN C    CD  1 
ATOM   3713 O OE1 . GLN B 2 3   ? 0.54700  43.51000 48.55800  1.000 141.25000 ?  3    GLN C    OE1 1 
ATOM   3714 N NE2 . GLN B 2 3   ? 0.79100  44.17400 46.43600  1.000 137.21000 ?  3    GLN C    NE2 1 
ATOM   3715 N N   . LEU B 2 4   ? 3.65700  44.21400 45.47200  1.000 135.09000 ?  4    LEU C    N   1 
ATOM   3716 C CA  . LEU B 2 4   ? 3.78200  44.78800 44.11100  1.000 131.16000 ?  4    LEU C    CA  1 
ATOM   3717 C C   . LEU B 2 4   ? 2.39800  45.30000 43.71500  1.000 133.38000 ?  4    LEU C    C   1 
ATOM   3718 O O   . LEU B 2 4   ? 1.45600  44.49000 43.74600  1.000 134.45000 ?  4    LEU C    O   1 
ATOM   3719 C CB  . LEU B 2 4   ? 4.23500  43.68300 43.15700  1.000 126.62000 ?  4    LEU C    CB  1 
ATOM   3720 C CG  . LEU B 2 4   ? 5.53500  42.97100 43.52100  1.000 129.94000 ?  4    LEU C    CG  1 
ATOM   3721 C CD1 . LEU B 2 4   ? 5.33700  41.46600 43.48300  1.000 129.09000 ?  4    LEU C    CD1 1 
ATOM   3722 C CD2 . LEU B 2 4   ? 6.64800  43.37500 42.56900  1.000 134.72000 ?  4    LEU C    CD2 1 
ATOM   3723 N N   . VAL B 2 5   ? 2.25900  46.58500 43.38100  1.000 131.12000 ?  5    VAL C    N   1 
ATOM   3724 C CA  . VAL B 2 5   ? 0.91400  47.06300 43.08900  1.000 130.59000 ?  5    VAL C    CA  1 
ATOM   3725 C C   . VAL B 2 5   ? 0.96800  47.75900 41.74000  1.000 131.66000 ?  5    VAL C    C   1 
ATOM   3726 O O   . VAL B 2 5   ? 1.67300  48.76200 41.58700  1.000 130.67000 ?  5    VAL C    O   1 
ATOM   3727 C CB  . VAL B 2 5   ? 0.37700  48.00700 44.17900  1.000 132.39000 ?  5    VAL C    CB  1 
ATOM   3728 C CG1 . VAL B 2 5   ? -0.76200 48.85600 43.63500  1.000 134.94000 ?  5    VAL C    CG1 1 
ATOM   3729 C CG2 . VAL B 2 5   ? -0.09100 47.20700 45.39400  1.000 131.64000 ?  5    VAL C    CG2 1 
ATOM   3730 N N   . GLU B 2 6   ? 0.24700  47.21000 40.76100  1.000 140.40000 ?  6    GLU C    N   1 
ATOM   3731 C CA  . GLU B 2 6   ? 0.22700  47.68800 39.38300  1.000 143.54000 ?  6    GLU C    CA  1 
ATOM   3732 C C   . GLU B 2 6   ? -0.61400 48.96000 39.27200  1.000 141.55000 ?  6    GLU C    C   1 
ATOM   3733 O O   . GLU B 2 6   ? -1.30500 49.36700 40.21200  1.000 138.17000 ?  6    GLU C    O   1 
ATOM   3734 C CB  . GLU B 2 6   ? -0.32200 46.60300 38.44600  1.000 141.54000 ?  6    GLU C    CB  1 
ATOM   3735 C CG  . GLU B 2 6   ? 0.62200  45.43000 38.17300  1.000 135.93000 ?  6    GLU C    CG  1 
ATOM   3736 C CD  . GLU B 2 6   ? -0.07500 44.08600 38.36300  1.000 137.68000 ?  6    GLU C    CD  1 
ATOM   3737 O OE1 . GLU B 2 6   ? -1.30700 44.07900 38.56900  1.000 138.42000 ?  6    GLU C    OE1 1 
ATOM   3738 O OE2 . GLU B 2 6   ? 0.59800  43.03800 38.32100  1.000 132.27000 -1 6    GLU C    OE2 1 
ATOM   3739 N N   . SER B 2 7   ? -0.54700 49.59000 38.10300  1.000 141.05000 ?  7    SER C    N   1 
ATOM   3740 C CA  . SER B 2 7   ? -1.27400 50.83000 37.86000  1.000 142.61000 ?  7    SER C    CA  1 
ATOM   3741 C C   . SER B 2 7   ? -1.35600 51.05600 36.35300  1.000 144.51000 ?  7    SER C    C   1 
ATOM   3742 O O   . SER B 2 7   ? -1.11700 50.13400 35.56300  1.000 141.91000 ?  7    SER C    O   1 
ATOM   3743 C CB  . SER B 2 7   ? -0.60900 52.00700 38.59500  1.000 138.22000 ?  7    SER C    CB  1 
ATOM   3744 O OG  . SER B 2 7   ? -1.20700 52.22400 39.86300  1.000 133.61000 ?  7    SER C    OG  1 
ATOM   3745 N N   . GLY B 2 8   ? -1.69300 52.28500 35.96000  1.000 144.87000 ?  8    GLY C    N   1 
ATOM   3746 C CA  . GLY B 2 8   ? -1.92300 52.61600 34.56900  1.000 142.25000 ?  8    GLY C    CA  1 
ATOM   3747 C C   . GLY B 2 8   ? -3.21500 52.02600 34.04600  1.000 148.60000 ?  8    GLY C    C   1 
ATOM   3748 O O   . GLY B 2 8   ? -4.13000 52.75800 33.65200  1.000 150.13000 ?  8    GLY C    O   1 
ATOM   3749 N N   . GLY B 2 9   ? -3.30200 50.69600 34.05500  1.000 148.83000 ?  9    GLY C    N   1 
ATOM   3750 C CA  . GLY B 2 9   ? -4.45200 49.98800 33.53200  1.000 147.64000 ?  9    GLY C    CA  1 
ATOM   3751 C C   . GLY B 2 9   ? -4.07500 49.10000 32.36400  1.000 145.15000 ?  9    GLY C    C   1 
ATOM   3752 O O   . GLY B 2 9   ? -3.10100 48.34900 32.44100  1.000 138.58000 ?  9    GLY C    O   1 
ATOM   3753 N N   . GLY B 2 10  ? -4.82900 49.18900 31.27400  1.000 146.42000 ?  10   GLY C    N   1 
ATOM   3754 C CA  . GLY B 2 10  ? -4.55500 48.40400 30.08700  1.000 139.45000 ?  10   GLY C    CA  1 
ATOM   3755 C C   . GLY B 2 10  ? -4.90900 49.14200 28.80800  1.000 144.85000 ?  10   GLY C    C   1 
ATOM   3756 O O   . GLY B 2 10  ? -6.08300 49.29900 28.46100  1.000 142.73000 ?  10   GLY C    O   1 
ATOM   3757 N N   . ARG B 2 19  ? 2.32700  50.48200 28.01300  1.000 150.77000 ?  19   ARG C    N   1 
ATOM   3758 C CA  . ARG B 2 19  ? 3.33500  50.63800 29.09400  1.000 152.26000 ?  19   ARG C    CA  1 
ATOM   3759 C C   . ARG B 2 19  ? 2.67100  50.37000 30.44500  1.000 152.85000 ?  19   ARG C    C   1 
ATOM   3760 O O   . ARG B 2 19  ? 2.02100  51.29300 30.96800  1.000 153.69000 ?  19   ARG C    O   1 
ATOM   3761 C CB  . ARG B 2 19  ? 3.93800  52.04600 29.07200  1.000 144.20000 ?  19   ARG C    CB  1 
ATOM   3762 C CG  . ARG B 2 19  ? 5.10100  52.23500 30.03500  1.000 142.69000 ?  19   ARG C    CG  1 
ATOM   3763 C CD  . ARG B 2 19  ? 5.82500  53.55000 29.82000  1.000 144.05000 ?  19   ARG C    CD  1 
ATOM   3764 N NE  . ARG B 2 19  ? 5.14500  54.70800 30.38600  1.000 148.45000 ?  19   ARG C    NE  1 
ATOM   3765 C CZ  . ARG B 2 19  ? 4.95000  54.91700 31.68300  1.000 145.73000 ?  19   ARG C    CZ  1 
ATOM   3766 N NH1 . ARG B 2 19  ? 5.17000  53.94800 32.55400  1.000 147.31000 ?  19   ARG C    NH1 1 
ATOM   3767 N NH2 . ARG B 2 19  ? 4.54000  56.10000 32.10700  1.000 135.06000 ?  19   ARG C    NH2 1 
ATOM   3768 N N   . LEU B 2 20  ? 2.79100  49.14800 30.96400  1.000 153.24000 ?  20   LEU C    N   1 
ATOM   3769 C CA  . LEU B 2 20  ? 2.27800  48.86800 32.32900  1.000 150.02000 ?  20   LEU C    CA  1 
ATOM   3770 C C   . LEU B 2 20  ? 3.32400  49.39700 33.31700  1.000 153.13000 ?  20   LEU C    C   1 
ATOM   3771 O O   . LEU B 2 20  ? 4.33700  49.94700 32.85000  1.000 157.73000 ?  20   LEU C    O   1 
ATOM   3772 C CB  . LEU B 2 20  ? 2.06700  47.36000 32.48700  1.000 144.18000 ?  20   LEU C    CB  1 
ATOM   3773 C CG  . LEU B 2 20  ? 0.98800  46.73800 31.60200  1.000 141.45000 ?  20   LEU C    CG  1 
ATOM   3774 C CD1 . LEU B 2 20  ? 1.50500  46.50900 30.19100  1.000 134.53000 ?  20   LEU C    CD1 1 
ATOM   3775 C CD2 . LEU B 2 20  ? 0.49100  45.43100 32.20000  1.000 144.87000 ?  20   LEU C    CD2 1 
ATOM   3776 N N   . SER B 2 21  ? 3.09700  49.24200 34.62200  1.000 151.51000 ?  21   SER C    N   1 
ATOM   3777 C CA  . SER B 2 21  ? 4.06300  49.67100 35.59700  1.000 148.78000 ?  21   SER C    CA  1 
ATOM   3778 C C   . SER B 2 21  ? 4.06200  48.81500 36.89900  1.000 147.14000 ?  21   SER C    C   1 
ATOM   3779 O O   . SER B 2 21  ? 2.94900  48.40300 37.27800  1.000 146.63000 ?  21   SER C    O   1 
ATOM   3780 C CB  . SER B 2 21  ? 3.83700  51.08400 36.06900  1.000 141.84000 ?  21   SER C    CB  1 
ATOM   3781 O OG  . SER B 2 21  ? 3.77700  51.95500 34.94900  1.000 140.18000 ?  21   SER C    OG  1 
ATOM   3782 N N   . CYS B 2 22  ? 5.19200  48.43000 37.46700  1.000 138.12000 ?  22   CYS C    N   1 
ATOM   3783 C CA  . CYS B 2 22  ? 5.04900  47.66500 38.70400  1.000 137.20000 ?  22   CYS C    CA  1 
ATOM   3784 C C   . CYS B 2 22  ? 6.26500  47.78700 39.70700  1.000 140.59000 ?  22   CYS C    C   1 
ATOM   3785 O O   . CYS B 2 22  ? 6.64300  46.74500 40.27000  1.000 139.39000 ?  22   CYS C    O   1 
ATOM   3786 C CB  . CYS B 2 22  ? 4.98200  46.20700 38.31800  1.000 134.38000 ?  22   CYS C    CB  1 
ATOM   3787 S SG  . CYS B 2 22  ? 4.69500  45.09500 39.71700  1.000 152.52000 ?  22   CYS C    SG  1 
ATOM   3788 N N   . ALA B 2 23  ? 6.84400  48.97900 39.91200  1.000 142.87000 ?  23   ALA C    N   1 
ATOM   3789 C CA  . ALA B 2 23  ? 7.85500  49.03200 40.96400  1.000 131.23000 ?  23   ALA C    CA  1 
ATOM   3790 C C   . ALA B 2 23  ? 7.21900  48.49600 42.25100  1.000 130.70000 ?  23   ALA C    C   1 
ATOM   3791 O O   . ALA B 2 23  ? 5.99900  48.30900 42.33500  1.000 128.96000 ?  23   ALA C    O   1 
ATOM   3792 C CB  . ALA B 2 23  ? 8.41600  50.45400 41.13200  1.000 108.46000 ?  23   ALA C    CB  1 
ATOM   3793 N N   . ALA B 2 24  ? 8.05000  48.19000 43.24500  1.000 123.10000 ?  24   ALA C    N   1 
ATOM   3794 C CA  . ALA B 2 24  ? 7.49700  47.64700 44.48400  1.000 122.22000 ?  24   ALA C    CA  1 
ATOM   3795 C C   . ALA B 2 24  ? 8.05200  48.34300 45.72400  1.000 131.07000 ?  24   ALA C    C   1 
ATOM   3796 O O   . ALA B 2 24  ? 8.71400  49.38200 45.61200  1.000 134.75000 ?  24   ALA C    O   1 
ATOM   3797 C CB  . ALA B 2 24  ? 7.76000  46.14700 44.55900  1.000 120.89000 ?  24   ALA C    CB  1 
ATOM   3798 N N   . SER B 2 25  ? 7.76200  47.79700 46.90900  1.000 128.50000 ?  25   SER C    N   1 
ATOM   3799 C CA  . SER B 2 25  ? 8.41200  48.18200 48.16200  1.000 126.29000 ?  25   SER C    CA  1 
ATOM   3800 C C   . SER B 2 25  ? 8.03600  47.16800 49.23300  1.000 129.42000 ?  25   SER C    C   1 
ATOM   3801 O O   . SER B 2 25  ? 6.94100  46.59700 49.19900  1.000 132.59000 ?  25   SER C    O   1 
ATOM   3802 C CB  . SER B 2 25  ? 8.02800  49.59700 48.60400  1.000 122.51000 ?  25   SER C    CB  1 
ATOM   3803 O OG  . SER B 2 25  ? 6.68800  49.87000 48.25000  1.000 132.58000 ?  25   SER C    OG  1 
ATOM   3804 N N   . GLY B 2 26  ? 8.95500  46.94300 50.17000  1.000 122.72000 ?  26   GLY C    N   1 
ATOM   3805 C CA  . GLY B 2 26  ? 8.77100  45.92500 51.18700  1.000 117.42000 ?  26   GLY C    CA  1 
ATOM   3806 C C   . GLY B 2 26  ? 10.01700 45.10400 51.41700  1.000 115.36000 ?  26   GLY C    C   1 
ATOM   3807 O O   . GLY B 2 26  ? 10.03600 44.24200 52.28600  1.000 119.63000 ?  26   GLY C    O   1 
ATOM   3808 N N   . ILE B 2 28  ? 15.83300 45.88500 49.81300  1.000 119.40000 ?  28   ILE C    N   1 
ATOM   3809 C CA  . ILE B 2 28  ? 16.55800 45.24100 50.90600  1.000 130.75000 ?  28   ILE C    CA  1 
ATOM   3810 C C   . ILE B 2 28  ? 17.42700 44.06900 50.35900  1.000 132.29000 ?  28   ILE C    C   1 
ATOM   3811 O O   . ILE B 2 28  ? 18.49400 43.77600 50.91300  1.000 131.59000 ?  28   ILE C    O   1 
ATOM   3812 C CB  . ILE B 2 28  ? 15.55200 44.80500 52.06500  1.000 128.32000 ?  28   ILE C    CB  1 
ATOM   3813 C CG1 . ILE B 2 28  ? 14.54800 45.93600 52.37300  1.000 120.20000 ?  28   ILE C    CG1 1 
ATOM   3814 C CG2 . ILE B 2 28  ? 16.28600 44.38100 53.36300  1.000 114.00000 ?  28   ILE C    CG2 1 
ATOM   3815 C CD1 . ILE B 2 28  ? 13.59800 45.66000 53.53300  1.000 112.19000 ?  28   ILE C    CD1 1 
ATOM   3816 N N   . LEU B 2 29  ? 16.95600 43.41000 49.29600  1.000 134.52000 ?  29   LEU C    N   1 
ATOM   3817 C CA  . LEU B 2 29  ? 17.68700 42.23300 48.74900  1.000 131.67000 ?  29   LEU C    CA  1 
ATOM   3818 C C   . LEU B 2 29  ? 18.64200 42.68900 47.64500  1.000 130.78000 ?  29   LEU C    C   1 
ATOM   3819 O O   . LEU B 2 29  ? 18.18900 43.40300 46.73300  1.000 131.26000 ?  29   LEU C    O   1 
ATOM   3820 C CB  . LEU B 2 29  ? 16.66300 41.21600 48.23700  1.000 126.60000 ?  29   LEU C    CB  1 
ATOM   3821 C CG  . LEU B 2 29  ? 15.82000 40.56700 49.33200  1.000 127.55000 ?  29   LEU C    CG  1 
ATOM   3822 C CD1 . LEU B 2 29  ? 15.44500 39.14500 48.95600  1.000 126.98000 ?  29   LEU C    CD1 1 
ATOM   3823 C CD2 . LEU B 2 29  ? 16.55900 40.58200 50.66000  1.000 121.08000 ?  29   LEU C    CD2 1 
ATOM   3824 N N   . PRO B 2 30  ? 19.93400 42.29900 47.67500  1.000 128.36000 ?  30   PRO C    N   1 
ATOM   3825 C CA  . PRO B 2 30  ? 20.92200 42.79600 46.70600  1.000 133.85000 ?  30   PRO C    CA  1 
ATOM   3826 C C   . PRO B 2 30  ? 20.84300 42.16400 45.30600  1.000 126.89000 ?  30   PRO C    C   1 
ATOM   3827 O O   . PRO B 2 30  ? 21.66300 42.50500 44.47600  1.000 120.03000 ?  30   PRO C    O   1 
ATOM   3828 C CB  . PRO B 2 30  ? 22.27200 42.43000 47.34900  1.000 124.60000 ?  30   PRO C    CB  1 
ATOM   3829 C CG  . PRO B 2 30  ? 21.93200 41.95300 48.74800  1.000 121.07000 ?  30   PRO C    CG  1 
ATOM   3830 C CD  . PRO B 2 30  ? 20.52900 41.39500 48.65200  1.000 117.79000 ?  30   PRO C    CD  1 
ATOM   3831 N N   . ILE B 2 31  ? 19.88200 41.26800 45.08200  1.000 119.95000 ?  31   ILE C    N   1 
ATOM   3832 C CA  . ILE B 2 31  ? 19.73900 40.59400 43.76000  1.000 120.25000 ?  31   ILE C    CA  1 
ATOM   3833 C C   . ILE B 2 31  ? 18.24700 40.50300 43.45400  1.000 126.42000 ?  31   ILE C    C   1 
ATOM   3834 O O   . ILE B 2 31  ? 17.51600 40.03200 44.34200  1.000 127.79000 ?  31   ILE C    O   1 
ATOM   3835 C CB  . ILE B 2 31  ? 20.40600 39.20900 43.80100  1.000 118.33000 ?  31   ILE C    CB  1 
ATOM   3836 C CG1 . ILE B 2 31  ? 21.90700 39.31400 44.07900  1.000 111.18000 ?  31   ILE C    CG1 1 
ATOM   3837 C CG2 . ILE B 2 31  ? 20.12400 38.43700 42.52200  1.000 124.83000 ?  31   ILE C    CG2 1 
ATOM   3838 C CD1 . ILE B 2 31  ? 22.61600 37.98400 44.11600  1.000 101.91000 ?  31   ILE C    CD1 1 
ATOM   3839 N N   . ASN B 2 32  ? 17.80800 40.90900 42.25400  1.000 127.63000 ?  32   ASN C    N   1 
ATOM   3840 C CA  . ASN B 2 32  ? 16.36100 40.93400 42.04100  1.000 121.96000 ?  32   ASN C    CA  1 
ATOM   3841 C C   . ASN B 2 32  ? 15.99900 40.82000 40.56800  1.000 119.79000 ?  32   ASN C    C   1 
ATOM   3842 O O   . ASN B 2 32  ? 16.54100 41.55200 39.73900  1.000 113.07000 ?  32   ASN C    O   1 
ATOM   3843 C CB  . ASN B 2 32  ? 15.78500 42.22700 42.59300  1.000 124.98000 ?  32   ASN C    CB  1 
ATOM   3844 C CG  . ASN B 2 32  ? 15.98400 42.34300 44.07300  1.000 132.21000 ?  32   ASN C    CG  1 
ATOM   3845 O OD1 . ASN B 2 32  ? 15.26400 41.72500 44.86800  1.000 132.11000 ?  32   ASN C    OD1 1 
ATOM   3846 N ND2 . ASN B 2 32  ? 17.02300 43.09400 44.46000  1.000 130.19000 ?  32   ASN C    ND2 1 
ATOM   3847 N N   . VAL B 2 33  ? 15.04000 39.94600 40.26200  1.000 129.58000 ?  33   VAL C    N   1 
ATOM   3848 C CA  . VAL B 2 33  ? 14.54400 39.72700 38.89500  1.000 130.03000 ?  33   VAL C    CA  1 
ATOM   3849 C C   . VAL B 2 33  ? 13.03300 39.96700 38.90300  1.000 129.94000 ?  33   VAL C    C   1 
ATOM   3850 O O   . VAL B 2 33  ? 12.24100 39.06000 39.19000  1.000 123.79000 ?  33   VAL C    O   1 
ATOM   3851 C CB  . VAL B 2 33  ? 14.86400 38.32400 38.36700  1.000 125.60000 ?  33   VAL C    CB  1 
ATOM   3852 C CG1 . VAL B 2 33  ? 14.77700 38.30900 36.84000  1.000 123.47000 ?  33   VAL C    CG1 1 
ATOM   3853 C CG2 . VAL B 2 33  ? 16.22300 37.82800 38.86600  1.000 122.73000 ?  33   VAL C    CG2 1 
ATOM   3854 N N   . MET B 2 34  ? 12.61300 41.18500 38.55100  1.000 132.32000 ?  34   MET C    N   1 
ATOM   3855 C CA  . MET B 2 34  ? 11.20000 41.47700 38.34200  1.000 131.03000 ?  34   MET C    CA  1 
ATOM   3856 C C   . MET B 2 34  ? 10.80000 41.15200 36.90900  1.000 132.81000 ?  34   MET C    C   1 
ATOM   3857 O O   . MET B 2 34  ? 11.58400 41.33400 35.97100  1.000 127.73000 ?  34   MET C    O   1 
ATOM   3858 C CB  . MET B 2 34  ? 10.87700 42.94200 38.63400  1.000 130.22000 ?  34   MET C    CB  1 
ATOM   3859 C CG  . MET B 2 34  ? 10.07300 43.13900 39.89900  1.000 129.39000 ?  34   MET C    CG  1 
ATOM   3860 S SD  . MET B 2 34  ? 9.81800  44.86600 40.26100  1.000 126.91000 ?  34   MET C    SD  1 
ATOM   3861 C CE  . MET B 2 34  ? 11.53700 45.40500 40.41700  1.000 127.08000 ?  34   MET C    CE  1 
ATOM   3862 N N   . GLY B 2 35  ? 9.55400  40.68600 36.74400  1.000 137.01000 ?  35   GLY C    N   1 
ATOM   3863 C CA  . GLY B 2 35  ? 9.08400  40.24300 35.44700  1.000 135.91000 ?  35   GLY C    CA  1 
ATOM   3864 C C   . GLY B 2 35  ? 7.60100  40.44900 35.20500  1.000 134.84000 ?  35   GLY C    C   1 
ATOM   3865 O O   . GLY B 2 35  ? 6.82200  40.74200 36.11200  1.000 133.03000 ?  35   GLY C    O   1 
ATOM   3866 N N   . TRP B 2 36  ? 7.23000  40.28900 33.93300  1.000 143.58000 ?  36   TRP C    N   1 
ATOM   3867 C CA  . TRP B 2 36  ? 5.84700  40.28700 33.45700  1.000 143.47000 ?  36   TRP C    CA  1 
ATOM   3868 C C   . TRP B 2 36  ? 5.54100  38.86300 33.00600  1.000 143.32000 ?  36   TRP C    C   1 
ATOM   3869 O O   . TRP B 2 36  ? 6.04700  38.41200 31.97800  1.000 142.44000 ?  36   TRP C    O   1 
ATOM   3870 C CB  . TRP B 2 36  ? 5.66000  41.29700 32.32600  1.000 137.34000 ?  36   TRP C    CB  1 
ATOM   3871 C CG  . TRP B 2 36  ? 5.50100  42.67200 32.86500  1.000 140.87000 ?  36   TRP C    CG  1 
ATOM   3872 C CD1 . TRP B 2 36  ? 6.38700  43.69600 32.75400  1.000 136.61000 ?  36   TRP C    CD1 1 
ATOM   3873 C CD2 . TRP B 2 36  ? 4.38400  43.18400 33.60200  1.000 144.13000 ?  36   TRP C    CD2 1 
ATOM   3874 N NE1 . TRP B 2 36  ? 5.90500  44.81000 33.39200  1.000 132.72000 ?  36   TRP C    NE1 1 
ATOM   3875 C CE2 . TRP B 2 36  ? 4.67100  44.52300 33.91300  1.000 140.54000 ?  36   TRP C    CE2 1 
ATOM   3876 C CE3 . TRP B 2 36  ? 3.16500  42.64100 34.02300  1.000 144.48000 ?  36   TRP C    CE3 1 
ATOM   3877 C CZ2 . TRP B 2 36  ? 3.78600  45.32800 34.62900  1.000 144.11000 ?  36   TRP C    CZ2 1 
ATOM   3878 C CZ3 . TRP B 2 36  ? 2.29100  43.43700 34.73900  1.000 143.82000 ?  36   TRP C    CZ3 1 
ATOM   3879 C CH2 . TRP B 2 36  ? 2.60500  44.76600 35.03500  1.000 145.89000 ?  36   TRP C    CH2 1 
ATOM   3880 N N   . TYR B 2 37  ? 4.75500  38.14400 33.80800  1.000 146.32000 ?  37   TYR C    N   1 
ATOM   3881 C CA  . TYR B 2 37  ? 4.26100  36.81000 33.47000  1.000 148.98000 ?  37   TYR C    CA  1 
ATOM   3882 C C   . TYR B 2 37  ? 2.82400  36.96400 32.97000  1.000 148.11000 ?  37   TYR C    C   1 
ATOM   3883 O O   . TYR B 2 37  ? 1.90300  37.17400 33.76900  1.000 145.74000 ?  37   TYR C    O   1 
ATOM   3884 C CB  . TYR B 2 37  ? 4.30800  35.87800 34.68200  1.000 145.90000 ?  37   TYR C    CB  1 
ATOM   3885 C CG  . TYR B 2 37  ? 5.48900  34.93200 34.76200  1.000 144.15000 ?  37   TYR C    CG  1 
ATOM   3886 C CD1 . TYR B 2 37  ? 6.79300  35.41300 34.81300  1.000 143.89000 ?  37   TYR C    CD1 1 
ATOM   3887 C CD2 . TYR B 2 37  ? 5.29300  33.55300 34.78400  1.000 145.19000 ?  37   TYR C    CD2 1 
ATOM   3888 C CE1 . TYR B 2 37  ? 7.86600  34.54600 34.90100  1.000 146.34000 ?  37   TYR C    CE1 1 
ATOM   3889 C CE2 . TYR B 2 37  ? 6.35800  32.67900 34.85800  1.000 147.68000 ?  37   TYR C    CE2 1 
ATOM   3890 C CZ  . TYR B 2 37  ? 7.64400  33.18100 34.91100  1.000 150.42000 ?  37   TYR C    CZ  1 
ATOM   3891 O OH  . TYR B 2 37  ? 8.70800  32.31200 34.98500  1.000 155.59000 ?  37   TYR C    OH  1 
ATOM   3892 N N   . ARG B 2 38  ? 2.63000  36.86300 31.65800  1.000 147.69000 ?  38   ARG C    N   1 
ATOM   3893 C CA  . ARG B 2 38  ? 1.31000  37.09000 31.06100  1.000 148.29000 ?  38   ARG C    CA  1 
ATOM   3894 C C   . ARG B 2 38  ? 0.53200  35.80600 30.81700  1.000 145.30000 ?  38   ARG C    C   1 
ATOM   3895 O O   . ARG B 2 38  ? 1.09900  34.72300 30.84500  1.000 148.48000 ?  38   ARG C    O   1 
ATOM   3896 C CB  . ARG B 2 38  ? 1.44900  37.86400 29.75100  1.000 147.57000 ?  38   ARG C    CB  1 
ATOM   3897 C CG  . ARG B 2 38  ? 1.48400  36.99200 28.50800  1.000 147.91000 ?  38   ARG C    CG  1 
ATOM   3898 C CD  . ARG B 2 38  ? 0.93800  37.70900 27.28500  1.000 144.06000 ?  38   ARG C    CD  1 
ATOM   3899 N NE  . ARG B 2 38  ? 0.72700  36.79700 26.16400  1.000 142.60000 ?  38   ARG C    NE  1 
ATOM   3900 C CZ  . ARG B 2 38  ? 1.55600  36.66400 25.13500  1.000 142.08000 ?  38   ARG C    CZ  1 
ATOM   3901 N NH1 . ARG B 2 38  ? 2.65900  37.38800 25.03300  1.000 138.41000 ?  38   ARG C    NH1 1 
ATOM   3902 N NH2 . ARG B 2 38  ? 1.26700  35.79000 24.17600  1.000 143.16000 ?  38   ARG C    NH2 1 
ATOM   3903 N N   . SER B 2 43  ? -6.84600 30.00200 29.68700  1.000 154.60000 ?  43   SER C    N   1 
ATOM   3904 C CA  . SER B 2 43  ? -5.47800 29.78700 29.21800  1.000 160.78000 ?  43   SER C    CA  1 
ATOM   3905 C C   . SER B 2 43  ? -4.59000 29.22800 30.33800  1.000 163.33000 ?  43   SER C    C   1 
ATOM   3906 O O   . SER B 2 43  ? -5.10600 28.69300 31.31700  1.000 166.82000 ?  43   SER C    O   1 
ATOM   3907 C CB  . SER B 2 43  ? -4.90200 31.09300 28.67900  1.000 157.07000 ?  43   SER C    CB  1 
ATOM   3908 O OG  . SER B 2 43  ? -5.91000 31.85000 28.03600  1.000 155.51000 ?  43   SER C    OG  1 
ATOM   3909 N N   . GLN B 2 44  ? -3.27000 29.38100 30.15900  1.000 163.03000 ?  44   GLN C    N   1 
ATOM   3910 C CA  . GLN B 2 44  ? -2.26100 28.97900 31.17800  1.000 168.62000 ?  44   GLN C    CA  1 
ATOM   3911 C C   . GLN B 2 44  ? -1.12800 30.00700 31.06200  1.000 169.67000 ?  44   GLN C    C   1 
ATOM   3912 O O   . GLN B 2 44  ? -0.56500 30.11600 29.95600  1.000 163.32000 ?  44   GLN C    O   1 
ATOM   3913 C CB  . GLN B 2 44  ? -1.77500 27.55300 30.92100  1.000 162.91000 ?  44   GLN C    CB  1 
ATOM   3914 C CG  . GLN B 2 44  ? -0.40900 27.24900 31.52000  1.000 166.93000 ?  44   GLN C    CG  1 
ATOM   3915 C CD  . GLN B 2 44  ? -0.38100 27.35900 33.02500  1.000 169.86000 ?  44   GLN C    CD  1 
ATOM   3916 O OE1 . GLN B 2 44  ? -0.57500 28.42900 33.59700  1.000 170.37000 ?  44   GLN C    OE1 1 
ATOM   3917 N NE2 . GLN B 2 44  ? -0.11500 26.24200 33.68300  1.000 162.02000 ?  44   GLN C    NE2 1 
ATOM   3918 N N   . ARG B 2 45  ? -0.79700 30.73700 32.13300  1.000 167.47000 ?  45   ARG C    N   1 
ATOM   3919 C CA  . ARG B 2 45  ? 0.19000  31.85300 32.03000  1.000 163.22000 ?  45   ARG C    CA  1 
ATOM   3920 C C   . ARG B 2 45  ? 1.62500  31.36200 31.79400  1.000 165.66000 ?  45   ARG C    C   1 
ATOM   3921 O O   . ARG B 2 45  ? 1.90300  30.19600 32.12600  1.000 166.39000 ?  45   ARG C    O   1 
ATOM   3922 C CB  . ARG B 2 45  ? 0.14200  32.70600 33.30000  1.000 160.55000 ?  45   ARG C    CB  1 
ATOM   3923 C CG  . ARG B 2 45  ? 0.68000  32.01000 34.54100  1.000 156.45000 ?  45   ARG C    CG  1 
ATOM   3924 C CD  . ARG B 2 45  ? 0.53000  32.87400 35.77800  1.000 151.43000 ?  45   ARG C    CD  1 
ATOM   3925 N NE  . ARG B 2 45  ? 0.99400  32.20600 36.98400  1.000 148.09000 ?  45   ARG C    NE  1 
ATOM   3926 C CZ  . ARG B 2 45  ? 0.93300  32.72900 38.20300  1.000 137.20000 ?  45   ARG C    CZ  1 
ATOM   3927 N NH1 . ARG B 2 45  ? 0.30600  33.87500 38.40000  1.000 131.00000 ?  45   ARG C    NH1 1 
ATOM   3928 N NH2 . ARG B 2 45  ? 1.49300  32.09900 39.22100  1.000 130.21000 ?  45   ARG C    NH2 1 
ATOM   3929 N N   . GLU B 2 46  ? 2.49800  32.23500 31.26600  1.000 162.26000 ?  46   GLU C    N   1 
ATOM   3930 C CA  . GLU B 2 46  ? 3.92800  31.88400 31.02200  1.000 158.51000 ?  46   GLU C    CA  1 
ATOM   3931 C C   . GLU B 2 46  ? 4.78300  33.15500 30.92600  1.000 155.28000 ?  46   GLU C    C   1 
ATOM   3932 O O   . GLU B 2 46  ? 4.22600  34.24800 31.13800  1.000 153.08000 ?  46   GLU C    O   1 
ATOM   3933 C CB  . GLU B 2 46  ? 4.06600  31.04900 29.75000  1.000 160.63000 ?  46   GLU C    CB  1 
ATOM   3934 C CG  . GLU B 2 46  ? 3.85600  29.56500 29.98300  1.000 166.90000 ?  46   GLU C    CG  1 
ATOM   3935 C CD  . GLU B 2 46  ? 4.68000  28.98700 31.12100  1.000 165.74000 ?  46   GLU C    CD  1 
ATOM   3936 O OE1 . GLU B 2 46  ? 5.92300  29.05100 31.04200  1.000 160.94000 ?  46   GLU C    OE1 1 
ATOM   3937 O OE2 . GLU B 2 46  ? 4.07800  28.47600 32.08500  1.000 164.94000 ?  46   GLU C    OE2 1 
ATOM   3938 N N   . LEU B 2 47  ? 6.09200  33.00500 30.72000  1.000 153.35000 ?  47   LEU C    N   1 
ATOM   3939 C CA  . LEU B 2 47  ? 6.99300  34.18800 30.74800  1.000 149.90000 ?  47   LEU C    CA  1 
ATOM   3940 C C   . LEU B 2 47  ? 6.68400  35.11600 29.57400  1.000 145.16000 ?  47   LEU C    C   1 
ATOM   3941 O O   . LEU B 2 47  ? 6.47500  34.61000 28.45900  1.000 146.30000 ?  47   LEU C    O   1 
ATOM   3942 C CB  . LEU B 2 47  ? 8.45000  33.71400 30.70300  1.000 150.28000 ?  47   LEU C    CB  1 
ATOM   3943 C CG  . LEU B 2 47  ? 9.51100  34.80500 30.84500  1.000 144.32000 ?  47   LEU C    CG  1 
ATOM   3944 C CD1 . LEU B 2 47  ? 9.77900  35.49200 29.51400  1.000 135.41000 ?  47   LEU C    CD1 1 
ATOM   3945 C CD2 . LEU B 2 47  ? 9.10500  35.82400 31.89700  1.000 143.92000 ?  47   LEU C    CD2 1 
ATOM   3946 N N   . VAL B 2 48  ? 6.64900  36.41900 29.83500  1.000 139.83000 ?  48   VAL C    N   1 
ATOM   3947 C CA  . VAL B 2 48  ? 6.46000  37.39600 28.72900  1.000 140.13000 ?  48   VAL C    CA  1 
ATOM   3948 C C   . VAL B 2 48  ? 7.58300  38.42700 28.84200  1.000 140.77000 ?  48   VAL C    C   1 
ATOM   3949 O O   . VAL B 2 48  ? 7.89500  39.07100 27.82400  1.000 137.67000 ?  48   VAL C    O   1 
ATOM   3950 C CB  . VAL B 2 48  ? 5.07200  38.05600 28.78300  1.000 144.56000 ?  48   VAL C    CB  1 
ATOM   3951 C CG1 . VAL B 2 48  ? 5.11000  39.40200 29.48800  1.000 144.01000 ?  48   VAL C    CG1 1 
ATOM   3952 C CG2 . VAL B 2 48  ? 4.48700  38.21700 27.39000  1.000 147.80000 ?  48   VAL C    CG2 1 
ATOM   3953 N N   . ALA B 2 49  ? 8.17300  38.55700 30.03600  1.000 143.22000 ?  49   ALA C    N   1 
ATOM   3954 C CA  . ALA B 2 49  ? 9.22500  39.58100 30.23500  1.000 137.36000 ?  49   ALA C    CA  1 
ATOM   3955 C C   . ALA B 2 49  ? 9.91700  39.46700 31.59700  1.000 136.44000 ?  49   ALA C    C   1 
ATOM   3956 O O   . ALA B 2 49  ? 9.21400  39.20500 32.58500  1.000 138.88000 ?  49   ALA C    O   1 
ATOM   3957 C CB  . ALA B 2 49  ? 8.62300  40.95100 30.05500  1.000 134.34000 ?  49   ALA C    CB  1 
ATOM   3958 N N   . THR B 2 50  ? 11.24000 39.63600 31.63600  1.000 134.59000 ?  50   THR C    N   1 
ATOM   3959 C CA  . THR B 2 50  ? 12.04200 39.66500 32.85800  1.000 129.84000 ?  50   THR C    CA  1 
ATOM   3960 C C   . THR B 2 50  ? 13.27800 40.53100 32.62200  1.000 126.60000 ?  50   THR C    C   1 
ATOM   3961 O O   . THR B 2 50  ? 13.92300 40.44500 31.57100  1.000 125.11000 ?  50   THR C    O   1 
ATOM   3962 C CB  . THR B 2 50  ? 12.49900 38.27200 33.34200  1.000 133.31000 ?  50   THR C    CB  1 
ATOM   3963 O OG1 . THR B 2 50  ? 12.80400 37.42600 32.22400  1.000 133.55000 ?  50   THR C    OG1 1 
ATOM   3964 C CG2 . THR B 2 50  ? 11.47100 37.61000 34.27900  1.000 133.38000 ?  50   THR C    CG2 1 
ATOM   3965 N N   . ILE B 2 51  ? 13.60100 41.35400 33.61900  1.000 122.80000 ?  51   ILE C    N   1 
ATOM   3966 C CA  . ILE B 2 51  ? 14.80600 42.17000 33.65800  1.000 115.88000 ?  51   ILE C    CA  1 
ATOM   3967 C C   . ILE B 2 51  ? 15.42600 41.95200 35.03700  1.000 122.31000 ?  51   ILE C    C   1 
ATOM   3968 O O   . ILE B 2 51  ? 14.74500 41.54400 35.98300  1.000 122.64000 ?  51   ILE C    O   1 
ATOM   3969 C CB  . ILE B 2 51  ? 14.47300 43.65900 33.39400  1.000 105.08000 ?  51   ILE C    CB  1 
ATOM   3970 C CG1 . ILE B 2 51  ? 15.63600 44.57200 33.72600  1.000 102.54000 ?  51   ILE C    CG1 1 
ATOM   3971 C CG2 . ILE B 2 51  ? 13.25200 44.07600 34.18400  1.000 103.36000 ?  51   ILE C    CG2 1 
ATOM   3972 C CD1 . ILE B 2 51  ? 15.35600 45.96500 33.41000  1.000 92.59000  ?  51   ILE C    CD1 1 
ATOM   3973 N N   . VAL B 2 52  ? 16.74200 42.18900 35.11000  1.000 119.80000 ?  52   VAL C    N   1 
ATOM   3974 C CA  . VAL B 2 52  ? 17.49500 42.01000 36.38500  1.000 121.36000 ?  52   VAL C    CA  1 
ATOM   3975 C C   . VAL B 2 52  ? 17.93300 43.38600 36.88800  1.000 115.71000 ?  52   VAL C    C   1 
ATOM   3976 O O   . VAL B 2 52  ? 18.36200 44.21100 36.06500  1.000 105.63000 ?  52   VAL C    O   1 
ATOM   3977 C CB  . VAL B 2 52  ? 18.71000 41.08600 36.18800  1.000 113.98000 ?  52   VAL C    CB  1 
ATOM   3978 C CG1 . VAL B 2 52  ? 18.28700 39.67800 35.80500  1.000 108.55000 ?  52   VAL C    CG1 1 
ATOM   3979 C CG2 . VAL B 2 52  ? 19.68700 41.64600 35.16700  1.000 104.68000 ?  52   VAL C    CG2 1 
ATOM   3980 N N   . THR B 2 53  ? 17.82900 43.60800 38.19700  1.000 122.84000 ?  53   THR C    N   1 
ATOM   3981 C CA  . THR B 2 53  ? 18.18200 44.92600 38.77700  1.000 120.92000 ?  53   THR C    CA  1 
ATOM   3982 C C   . THR B 2 53  ? 19.18700 44.73800 39.91300  1.000 118.46000 ?  53   THR C    C   1 
ATOM   3983 O O   . THR B 2 53  ? 18.83300 44.06800 40.90100  1.000 116.83000 ?  53   THR C    O   1 
ATOM   3984 C CB  . THR B 2 53  ? 16.92900 45.64500 39.27900  1.000 125.78000 ?  53   THR C    CB  1 
ATOM   3985 O OG1 . THR B 2 53  ? 15.90900 45.49600 38.29100  1.000 118.41000 ?  53   THR C    OG1 1 
ATOM   3986 C CG2 . THR B 2 53  ? 17.17200 47.11100 39.56500  1.000 125.00000 ?  53   THR C    CG2 1 
ATOM   3987 N N   . SER B 2 54  ? 20.38600 45.29900 39.76500  1.000 120.44000 ?  54   SER C    N   1 
ATOM   3988 C CA  . SER B 2 54  ? 21.42500 45.23700 40.82900  1.000 117.64000 ?  54   SER C    CA  1 
ATOM   3989 C C   . SER B 2 54  ? 21.84000 43.80200 41.17000  1.000 108.60000 ?  54   SER C    C   1 
ATOM   3990 O O   . SER B 2 54  ? 21.08300 43.12300 41.88700  1.000 106.03000 ?  54   SER C    O   1 
ATOM   3991 C CB  . SER B 2 54  ? 20.98900 45.99100 42.05400  1.000 113.14000 ?  54   SER C    CB  1 
ATOM   3992 O OG  . SER B 2 54  ? 20.81800 47.36900 41.75700  1.000 106.34000 ?  54   SER C    OG  1 
ATOM   3993 N N   . GLY B 2 55  ? 22.98800 43.36000 40.65700  1.000 98.06000  ?  55   GLY C    N   1 
ATOM   3994 C CA  . GLY B 2 55  ? 23.56200 42.05100 41.01200  1.000 95.07000  ?  55   GLY C    CA  1 
ATOM   3995 C C   . GLY B 2 55  ? 24.99900 41.92500 40.55300  1.000 95.16000  ?  55   GLY C    C   1 
ATOM   3996 O O   . GLY B 2 55  ? 25.78400 42.84800 40.82500  1.000 89.34000  ?  55   GLY C    O   1 
ATOM   3997 N N   . GLY B 2 56  ? 25.32800 40.83100 39.86600  1.000 95.54000  ?  56   GLY C    N   1 
ATOM   3998 C CA  . GLY B 2 56  ? 26.70600 40.58900 39.47600  1.000 89.06000  ?  56   GLY C    CA  1 
ATOM   3999 C C   . GLY B 2 56  ? 27.03500 40.85900 38.02000  1.000 88.36000  ?  56   GLY C    C   1 
ATOM   4000 O O   . GLY B 2 56  ? 27.17600 42.01400 37.61100  1.000 91.05000  ?  56   GLY C    O   1 
ATOM   4001 N N   . SER B 2 57  ? 27.21000 39.79000 37.23700  1.000 93.28000  ?  57   SER C    N   1 
ATOM   4002 C CA  . SER B 2 57  ? 27.40200 39.91800 35.79400  1.000 86.88000  ?  57   SER C    CA  1 
ATOM   4003 C C   . SER B 2 57  ? 26.10500 40.21500 35.08500  1.000 89.23000  ?  57   SER C    C   1 
ATOM   4004 O O   . SER B 2 57  ? 26.07200 41.05300 34.18000  1.000 97.36000  ?  57   SER C    O   1 
ATOM   4005 C CB  . SER B 2 57  ? 27.99000 38.64600 35.20500  1.000 82.69000  ?  57   SER C    CB  1 
ATOM   4006 O OG  . SER B 2 57  ? 29.35300 38.55600 35.52200  1.000 86.93000  ?  57   SER C    OG  1 
ATOM   4007 N N   . THR B 2 58  ? 25.05500 39.49700 35.46800  1.000 84.97000  ?  58   THR C    N   1 
ATOM   4008 C CA  . THR B 2 58  ? 23.71900 39.77500 34.89900  1.000 89.31000  ?  58   THR C    CA  1 
ATOM   4009 C C   . THR B 2 58  ? 23.34400 41.09900 35.55800  1.000 95.14000  ?  58   THR C    C   1 
ATOM   4010 O O   . THR B 2 58  ? 22.53400 41.07300 36.48600  1.000 96.65000  ?  58   THR C    O   1 
ATOM   4011 C CB  . THR B 2 58  ? 22.74900 38.65300 35.26600  1.000 87.40000  ?  58   THR C    CB  1 
ATOM   4012 O OG1 . THR B 2 58  ? 22.71800 38.56200 36.69000  1.000 90.09000  ?  58   THR C    OG1 1 
ATOM   4013 C CG2 . THR B 2 58  ? 23.15000 37.31800 34.68200  1.000 88.32000  ?  58   THR C    CG2 1 
ATOM   4014 N N   . ALA B 2 59  ? 23.95300 42.20200 35.12200  1.000 97.20000  ?  59   ALA C    N   1 
ATOM   4015 C CA  . ALA B 2 59  ? 23.70900 43.51100 35.76700  1.000 96.84000  ?  59   ALA C    CA  1 
ATOM   4016 C C   . ALA B 2 59  ? 22.34000 43.97900 35.28100  1.000 99.04000  ?  59   ALA C    C   1 
ATOM   4017 O O   . ALA B 2 59  ? 21.43700 44.11600 36.12300  1.000 87.80000  ?  59   ALA C    O   1 
ATOM   4018 C CB  . ALA B 2 59  ? 24.77100 44.50200 35.37800  1.000 95.63000  ?  59   ALA C    CB  1 
ATOM   4019 N N   . GLY B 2 60  ? 22.19500 44.20600 33.97600  1.000 103.93000 ?  60   GLY C    N   1 
ATOM   4020 C CA  . GLY B 2 60  ? 20.92500 44.74200 33.44900  1.000 99.19000  ?  60   GLY C    CA  1 
ATOM   4021 C C   . GLY B 2 60  ? 20.34900 43.86700 32.35600  1.000 97.79000  ?  60   GLY C    C   1 
ATOM   4022 O O   . GLY B 2 60  ? 19.54000 44.37300 31.56400  1.000 93.30000  ?  60   GLY C    O   1 
ATOM   4023 N N   . ASN B 2 61  ? 20.75700 42.59900 32.30900  1.000 101.22000 ?  61   ASN C    N   1 
ATOM   4024 C CA  . ASN B 2 61  ? 20.28400 41.74100 31.23000  1.000 101.22000 ?  61   ASN C    CA  1 
ATOM   4025 C C   . ASN B 2 61  ? 18.75900 41.77300 31.16000  1.000 108.99000 ?  61   ASN C    C   1 
ATOM   4026 O O   . ASN B 2 61  ? 18.06600 42.13400 32.12000  1.000 110.57000 ?  61   ASN C    O   1 
ATOM   4027 C CB  . ASN B 2 61  ? 20.77700 40.30600 31.42800  1.000 92.54000  ?  61   ASN C    CB  1 
ATOM   4028 C CG  . ASN B 2 61  ? 22.29300 40.17200 31.26800  1.000 98.71000  ?  61   ASN C    CG  1 
ATOM   4029 O OD1 . ASN B 2 61  ? 22.97600 41.06700 30.74400  1.000 99.59000  ?  61   ASN C    OD1 1 
ATOM   4030 N ND2 . ASN B 2 61  ? 22.82800 39.04100 31.73300  1.000 90.61000  ?  61   ASN C    ND2 1 
ATOM   4031 N N   . THR B 2 62  ? 18.23700 41.39300 29.99600  1.000 111.24000 ?  62   THR C    N   1 
ATOM   4032 C CA  . THR B 2 62  ? 16.82600 41.56900 29.66100  1.000 113.12000 ?  62   THR C    CA  1 
ATOM   4033 C C   . THR B 2 62  ? 16.36200 40.36900 28.84300  1.000 117.82000 ?  62   THR C    C   1 
ATOM   4034 O O   . THR B 2 62  ? 16.89000 40.13300 27.75300  1.000 123.33000 ?  62   THR C    O   1 
ATOM   4035 C CB  . THR B 2 62  ? 16.62300 42.88100 28.88100  1.000 108.14000 ?  62   THR C    CB  1 
ATOM   4036 O OG1 . THR B 2 62  ? 17.50500 42.91300 27.75300  1.000 104.73000 ?  62   THR C    OG1 1 
ATOM   4037 C CG2 . THR B 2 62  ? 16.92500 44.09900 29.75400  1.000 102.66000 ?  62   THR C    CG2 1 
ATOM   4038 N N   . ASN B 2 63  ? 15.37000 39.62200 29.34800  1.000 119.90000 ?  63   ASN C    N   1 
ATOM   4039 C CA  . ASN B 2 63  ? 14.95000 38.33800 28.77000  1.000 127.41000 ?  63   ASN C    CA  1 
ATOM   4040 C C   . ASN B 2 63  ? 13.46600 38.35600 28.39200  1.000 133.31000 ?  63   ASN C    C   1 
ATOM   4041 O O   . ASN B 2 63  ? 12.60300 38.30900 29.27500  1.000 135.41000 ?  63   ASN C    O   1 
ATOM   4042 C CB  . ASN B 2 63  ? 15.22600 37.19400 29.75200  1.000 130.48000 ?  63   ASN C    CB  1 
ATOM   4043 C CG  . ASN B 2 63  ? 14.66300 35.84700 29.27900  1.000 131.00000 ?  63   ASN C    CG  1 
ATOM   4044 O OD1 . ASN B 2 63  ? 14.81200 35.46600 28.11500  1.000 128.76000 ?  63   ASN C    OD1 1 
ATOM   4045 N ND2 . ASN B 2 63  ? 14.00800 35.12600 30.18900  1.000 131.68000 ?  63   ASN C    ND2 1 
ATOM   4046 N N   . TYR B 2 64  ? 13.16900 38.36100 27.08400  1.000 132.59000 ?  64   TYR C    N   1 
ATOM   4047 C CA  . TYR B 2 64  ? 11.81000 38.37400 26.54200  1.000 126.88000 ?  64   TYR C    CA  1 
ATOM   4048 C C   . TYR B 2 64  ? 11.50200 36.96000 26.03900  1.000 126.71000 ?  64   TYR C    C   1 
ATOM   4049 O O   . TYR B 2 64  ? 12.39700 36.13100 25.87900  1.000 128.52000 ?  64   TYR C    O   1 
ATOM   4050 C CB  . TYR B 2 64  ? 11.70100 39.39600 25.40000  1.000 119.59000 ?  64   TYR C    CB  1 
ATOM   4051 C CG  . TYR B 2 64  ? 12.00200 40.83900 25.78000  1.000 116.90000 ?  64   TYR C    CG  1 
ATOM   4052 C CD1 . TYR B 2 64  ? 10.99400 41.68300 26.23500  1.000 118.01000 ?  64   TYR C    CD1 1 
ATOM   4053 C CD2 . TYR B 2 64  ? 13.29000 41.35800 25.68900  1.000 117.28000 ?  64   TYR C    CD2 1 
ATOM   4054 C CE1 . TYR B 2 64  ? 11.25700 43.01400 26.58000  1.000 111.84000 ?  64   TYR C    CE1 1 
ATOM   4055 C CE2 . TYR B 2 64  ? 13.56300 42.69000 26.03800  1.000 116.93000 ?  64   TYR C    CE2 1 
ATOM   4056 C CZ  . TYR B 2 64  ? 12.53900 43.51100 26.48300  1.000 108.05000 ?  64   TYR C    CZ  1 
ATOM   4057 O OH  . TYR B 2 64  ? 12.79000 44.82200 26.83200  1.000 97.27000  ?  64   TYR C    OH  1 
ATOM   4058 N N   . VAL B 2 65  ? 10.20900 36.69200 25.78500  1.000 133.04000 ?  65   VAL C    N   1 
ATOM   4059 C CA  . VAL B 2 65  ? 9.75800  35.37000 25.30400  1.000 135.82000 ?  65   VAL C    CA  1 
ATOM   4060 C C   . VAL B 2 65  ? 9.67800  35.26200 23.78100  1.000 142.39000 ?  65   VAL C    C   1 
ATOM   4061 O O   . VAL B 2 65  ? 10.36900 34.43700 23.17300  1.000 149.98000 ?  65   VAL C    O   1 
ATOM   4062 C CB  . VAL B 2 65  ? 8.35600  35.01500 25.83300  1.000 30.00000  ?  65   VAL C    CB  1 
ATOM   4063 C CG1 . VAL B 2 65  ? 7.32700  36.01400 25.32800  1.000 30.00000  ?  65   VAL C    CG1 1 
ATOM   4064 C CG2 . VAL B 2 65  ? 7.97700  33.59900 25.42900  1.000 30.00000  ?  65   VAL C    CG2 1 
ATOM   4065 N N   . ASP B 2 66  ? 8.81800  36.08200 23.15700  1.000 144.49000 ?  66   ASP C    N   1 
ATOM   4066 C CA  . ASP B 2 66  ? 8.76200  36.24600 21.69900  1.000 145.42000 ?  66   ASP C    CA  1 
ATOM   4067 C C   . ASP B 2 66  ? 8.14000  37.55400 21.20700  1.000 141.13000 ?  66   ASP C    C   1 
ATOM   4068 O O   . ASP B 2 66  ? 7.04300  37.54400 20.63300  1.000 135.73000 ?  66   ASP C    O   1 
ATOM   4069 C CB  . ASP B 2 66  ? 8.04600  35.06200 21.02700  1.000 143.63000 ?  66   ASP C    CB  1 
ATOM   4070 C CG  . ASP B 2 66  ? 8.92300  33.82000 20.92800  1.000 150.75000 ?  66   ASP C    CG  1 
ATOM   4071 O OD1 . ASP B 2 66  ? 9.98100  33.88400 20.25500  1.000 150.69000 -1 66   ASP C    OD1 1 
ATOM   4072 O OD2 . ASP B 2 66  ? 8.55400  32.78200 21.52000  1.000 153.02000 ?  66   ASP C    OD2 1 
ATOM   4073 N N   . SER B 2 67  ? 8.84200  38.67300 21.40800  1.000 134.62000 ?  67   SER C    N   1 
ATOM   4074 C CA  . SER B 2 67  ? 8.34100  39.99700 21.02900  1.000 127.94000 ?  67   SER C    CA  1 
ATOM   4075 C C   . SER B 2 67  ? 9.45500  40.93300 20.53800  1.000 123.67000 ?  67   SER C    C   1 
ATOM   4076 O O   . SER B 2 67  ? 10.32500 40.54100 19.75300  1.000 113.90000 ?  67   SER C    O   1 
ATOM   4077 C CB  . SER B 2 67  ? 7.61000  40.64000 22.20900  1.000 117.05000 ?  67   SER C    CB  1 
ATOM   4078 O OG  . SER B 2 67  ? 6.48300  39.86800 22.57900  1.000 113.45000 ?  67   SER C    OG  1 
ATOM   4079 N N   . ALA B 2 96  ? -5.10600 36.50500 28.11000  1.000 153.47000 ?  96   ALA C    N   1 
ATOM   4080 C CA  . ALA B 2 96  ? -3.94200 37.36400 28.28300  1.000 154.52000 ?  96   ALA C    CA  1 
ATOM   4081 C C   . ALA B 2 96  ? -4.05400 38.23700 29.53700  1.000 144.33000 ?  96   ALA C    C   1 
ATOM   4082 O O   . ALA B 2 96  ? -4.18800 39.45200 29.41400  1.000 143.02000 ?  96   ALA C    O   1 
ATOM   4083 C CB  . ALA B 2 96  ? -3.74300 38.24500 27.03300  1.000 144.83000 ?  96   ALA C    CB  1 
ATOM   4084 N N   . VAL B 2 97  ? -3.97500 37.62900 30.72500  1.000 142.86000 ?  97   VAL C    N   1 
ATOM   4085 C CA  . VAL B 2 97  ? -4.08200 38.34500 32.00400  1.000 150.54000 ?  97   VAL C    CA  1 
ATOM   4086 C C   . VAL B 2 97  ? -2.68100 38.55200 32.59400  1.000 146.97000 ?  97   VAL C    C   1 
ATOM   4087 O O   . VAL B 2 97  ? -2.11900 37.67000 33.25300  1.000 143.19000 ?  97   VAL C    O   1 
ATOM   4088 C CB  . VAL B 2 97  ? -5.02500 37.63000 32.98400  1.000 146.97000 ?  97   VAL C    CB  1 
ATOM   4089 C CG1 . VAL B 2 97  ? -4.64800 36.15300 33.17300  1.000 148.70000 ?  97   VAL C    CG1 1 
ATOM   4090 C CG2 . VAL B 2 97  ? -5.01200 38.34400 34.32900  1.000 136.12000 ?  97   VAL C    CG2 1 
ATOM   4091 N N   . TYR B 2 98  ? -2.12600 39.74900 32.38600  1.000 144.57000 ?  98   TYR C    N   1 
ATOM   4092 C CA  . TYR B 2 98  ? -0.75900 40.03400 32.80800  1.000 143.89000 ?  98   TYR C    CA  1 
ATOM   4093 C C   . TYR B 2 98  ? -0.63100 40.00900 34.31700  1.000 142.63000 ?  98   TYR C    C   1 
ATOM   4094 O O   . TYR B 2 98  ? -1.47900 40.53800 35.03600  1.000 145.74000 ?  98   TYR C    O   1 
ATOM   4095 C CB  . TYR B 2 98  ? -0.29900 41.40100 32.30600  1.000 144.21000 ?  98   TYR C    CB  1 
ATOM   4096 C CG  . TYR B 2 98  ? 0.12600  41.45400 30.86100  1.000 144.42000 ?  98   TYR C    CG  1 
ATOM   4097 C CD1 . TYR B 2 98  ? -0.53000 40.71300 29.87900  1.000 143.56000 ?  98   TYR C    CD1 1 
ATOM   4098 C CD2 . TYR B 2 98  ? 1.17100  42.27800 30.47100  1.000 144.61000 ?  98   TYR C    CD2 1 
ATOM   4099 C CE1 . TYR B 2 98  ? -0.13800 40.77800 28.55200  1.000 142.74000 ?  98   TYR C    CE1 1 
ATOM   4100 C CE2 . TYR B 2 98  ? 1.56500  42.35300 29.15100  1.000 145.81000 ?  98   TYR C    CE2 1 
ATOM   4101 C CZ  . TYR B 2 98  ? 0.91300  41.60400 28.20000  1.000 141.23000 ?  98   TYR C    CZ  1 
ATOM   4102 O OH  . TYR B 2 98  ? 1.32600  41.70200 26.90000  1.000 130.45000 ?  98   TYR C    OH  1 
ATOM   4103 N N   . TYR B 2 99  ? 0.45500  39.41500 34.79000  1.000 140.60000 ?  99   TYR C    N   1 
ATOM   4104 C CA  . TYR B 2 99  ? 0.81000  39.44200 36.19600  1.000 143.28000 ?  99   TYR C    CA  1 
ATOM   4105 C C   . TYR B 2 99  ? 2.17700  40.10300 36.33600  1.000 147.24000 ?  99   TYR C    C   1 
ATOM   4106 O O   . TYR B 2 99  ? 2.96800  40.13700 35.38700  1.000 142.47000 ?  99   TYR C    O   1 
ATOM   4107 C CB  . TYR B 2 99  ? 0.82400  38.02400 36.79000  1.000 142.05000 ?  99   TYR C    CB  1 
ATOM   4108 C CG  . TYR B 2 99  ? -0.52500 37.34000 36.72800  1.000 144.72000 ?  99   TYR C    CG  1 
ATOM   4109 C CD1 . TYR B 2 99  ? -1.60100 37.79400 37.48900  1.000 139.00000 ?  99   TYR C    CD1 1 
ATOM   4110 C CD2 . TYR B 2 99  ? -0.72800 36.25100 35.88900  1.000 145.25000 ?  99   TYR C    CD2 1 
ATOM   4111 C CE1 . TYR B 2 99  ? -2.82800 37.17800 37.42100  1.000 135.34000 ?  99   TYR C    CE1 1 
ATOM   4112 C CE2 . TYR B 2 99  ? -1.95300 35.63000 35.81700  1.000 144.62000 ?  99   TYR C    CE2 1 
ATOM   4113 C CZ  . TYR B 2 99  ? -2.99600 36.09700 36.58400  1.000 141.69000 ?  99   TYR C    CZ  1 
ATOM   4114 O OH  . TYR B 2 99  ? -4.21300 35.47100 36.50700  1.000 147.95000 ?  99   TYR C    OH  1 
ATOM   4115 N N   . CYS B 2 100 ? 2.44600  40.65000 37.52200  1.000 151.10000 ?  100  CYS C    N   1 
ATOM   4116 C CA  . CYS B 2 100 ? 3.75400  41.20500 37.85000  1.000 144.90000 ?  100  CYS C    CA  1 
ATOM   4117 C C   . CYS B 2 100 ? 4.52000  40.21600 38.72500  1.000 137.05000 ?  100  CYS C    C   1 
ATOM   4118 O O   . CYS B 2 100 ? 3.94400  39.57000 39.60200  1.000 132.25000 ?  100  CYS C    O   1 
ATOM   4119 C CB  . CYS B 2 100 ? 3.63300  42.55800 38.56300  1.000 143.34000 ?  100  CYS C    CB  1 
ATOM   4120 S SG  . CYS B 2 100 ? 5.24100  43.28700 39.00600  1.000 150.75000 ?  100  CYS C    SG  1 
ATOM   4121 N N   . ASN B 2 101 ? 5.81700  40.09600 38.46800  1.000 138.00000 ?  101  ASN C    N   1 
ATOM   4122 C CA  . ASN B 2 101 ? 6.70100  39.16600 39.15300  1.000 138.35000 ?  101  ASN C    CA  1 
ATOM   4123 C C   . ASN B 2 101 ? 7.71300  39.93800 39.99800  1.000 133.06000 ?  101  ASN C    C   1 
ATOM   4124 O O   . ASN B 2 101 ? 7.90500  41.14800 39.84300  1.000 125.37000 ?  101  ASN C    O   1 
ATOM   4125 C CB  . ASN B 2 101 ? 7.41400  38.25700 38.12800  1.000 137.56000 ?  101  ASN C    CB  1 
ATOM   4126 C CG  . ASN B 2 101 ? 7.84900  36.90500 38.70600  1.000 136.79000 ?  101  ASN C    CG  1 
ATOM   4127 O OD1 . ASN B 2 101 ? 7.23700  36.37000 39.63500  1.000 132.46000 ?  101  ASN C    OD1 1 
ATOM   4128 N ND2 . ASN B 2 101 ? 8.90600  36.33700 38.12400  1.000 137.18000 ?  101  ASN C    ND2 1 
ATOM   4129 N N   . LEU B 2 102 ? 8.31800  39.22300 40.94000  1.000 127.64000 ?  102  LEU C    N   1 
ATOM   4130 C CA  . LEU B 2 102 ? 9.54300  39.68500 41.58000  1.000 128.22000 ?  102  LEU C    CA  1 
ATOM   4131 C C   . LEU B 2 102 ? 10.14800 38.46600 42.25300  1.000 129.34000 ?  102  LEU C    C   1 
ATOM   4132 O O   . LEU B 2 102 ? 9.56600  37.94100 43.20500  1.000 129.51000 ?  102  LEU C    O   1 
ATOM   4133 C CB  . LEU B 2 102 ? 9.28800  40.82500 42.57300  1.000 121.53000 ?  102  LEU C    CB  1 
ATOM   4134 C CG  . LEU B 2 102 ? 10.44000 41.40800 43.41600  1.000 106.90000 ?  102  LEU C    CG  1 
ATOM   4135 C CD1 . LEU B 2 102 ? 11.74700 41.57000 42.68800  1.000 105.31000 ?  102  LEU C    CD1 1 
ATOM   4136 C CD2 . LEU B 2 102 ? 10.01500 42.74900 43.89300  1.000 110.71000 ?  102  LEU C    CD2 1 
ATOM   4137 N N   . LYS B 2 103 ? 11.26200 37.98400 41.71000  1.000 127.18000 ?  103  LYS C    N   1 
ATOM   4138 C CA  . LYS B 2 103 ? 12.12400 37.05900 42.42100  1.000 119.63000 ?  103  LYS C    CA  1 
ATOM   4139 C C   . LYS B 2 103 ? 13.09000 37.86700 43.27900  1.000 121.11000 ?  103  LYS C    C   1 
ATOM   4140 O O   . LYS B 2 103 ? 13.70300 38.83200 42.80700  1.000 116.81000 ?  103  LYS C    O   1 
ATOM   4141 C CB  . LYS B 2 103 ? 12.87600 36.15200 41.45300  1.000 129.95000 ?  103  LYS C    CB  1 
ATOM   4142 C CG  . LYS B 2 103 ? 11.98800 35.16500 40.69400  1.000 137.00000 ?  103  LYS C    CG  1 
ATOM   4143 C CD  . LYS B 2 103 ? 12.83000 34.32600 39.73400  1.000 141.46000 ?  103  LYS C    CD  1 
ATOM   4144 C CE  . LYS B 2 103 ? 11.99600 33.31200 38.97800  1.000 153.05000 ?  103  LYS C    CE  1 
ATOM   4145 N NZ  . LYS B 2 103 ? 12.85500 32.54200 38.03000  1.000 159.16000 ?  103  LYS C    NZ  1 
ATOM   4146 N N   . THR B 2 104 ? 13.17700 37.49900 44.55500  1.000 127.29000 ?  104  THR C    N   1 
ATOM   4147 C CA  . THR B 2 104 ? 13.99100 38.19200 45.54400  1.000 125.21000 ?  104  THR C    CA  1 
ATOM   4148 C C   . THR B 2 104 ? 14.98600 37.21600 46.13900  1.000 119.66000 ?  104  THR C    C   1 
ATOM   4149 O O   . THR B 2 104 ? 14.64600 36.06200 46.42100  1.000 115.41000 ?  104  THR C    O   1 
ATOM   4150 C CB  . THR B 2 104 ? 13.14100 38.80000 46.66000  1.000 122.12000 ?  104  THR C    CB  1 
ATOM   4151 O OG1 . THR B 2 104 ? 12.67100 37.76300 47.53500  1.000 118.15000 ?  104  THR C    OG1 1 
ATOM   4152 C CG2 . THR B 2 104 ? 11.98500 39.56400 46.08300  1.000 121.49000 ?  104  THR C    CG2 1 
ATOM   4153 N N   . ARG B 2 105 ? 16.21900 37.68100 46.31100  1.000 114.52000 ?  105  ARG C    N   1 
ATOM   4154 C CA  . ARG B 2 105 ? 17.30400 36.79100 46.67900  1.000 117.20000 ?  105  ARG C    CA  1 
ATOM   4155 C C   . ARG B 2 105 ? 18.40800 37.62800 47.28700  1.000 115.10000 ?  105  ARG C    C   1 
ATOM   4156 O O   . ARG B 2 105 ? 18.70400 38.70800 46.77300  1.000 121.16000 ?  105  ARG C    O   1 
ATOM   4157 C CB  . ARG B 2 105 ? 17.87600 36.03500 45.46800  1.000 121.56000 ?  105  ARG C    CB  1 
ATOM   4158 C CG  . ARG B 2 105 ? 16.91900 35.22000 44.60600  1.000 123.28000 ?  105  ARG C    CG  1 
ATOM   4159 C CD  . ARG B 2 105 ? 17.58700 33.99000 44.03000  1.000 120.35000 ?  105  ARG C    CD  1 
ATOM   4160 N NE  . ARG B 2 105 ? 18.22300 34.14000 42.72800  1.000 117.37000 ?  105  ARG C    NE  1 
ATOM   4161 C CZ  . ARG B 2 105 ? 18.80900 33.13200 42.09200  1.000 117.87000 ?  105  ARG C    CZ  1 
ATOM   4162 N NH1 . ARG B 2 105 ? 18.85700 31.91200 42.62000  1.000 108.41000 ?  105  ARG C    NH1 1 
ATOM   4163 N NH2 . ARG B 2 105 ? 19.34800 33.34600 40.89400  1.000 117.30000 ?  105  ARG C    NH2 1 
ATOM   4164 N N   . ARG B 2 106 ? 19.03200 37.08800 48.33700  1.000 106.19000 ?  106  ARG C    N   1 
ATOM   4165 C CA  . ARG B 2 106 ? 20.11700 37.80500 49.05000  1.000 111.17000 ?  106  ARG C    CA  1 
ATOM   4166 C C   . ARG B 2 106 ? 21.45900 37.52600 48.37900  1.000 109.91000 ?  106  ARG C    C   1 
ATOM   4167 O O   . ARG B 2 106 ? 22.25800 38.46800 48.24700  1.000 98.52000  ?  106  ARG C    O   1 
ATOM   4168 C CB  . ARG B 2 106 ? 20.19400 37.29100 50.48700  1.000 114.76000 ?  106  ARG C    CB  1 
ATOM   4169 C CG  . ARG B 2 106 ? 18.83500 37.02100 51.11700  1.000 117.27000 ?  106  ARG C    CG  1 
ATOM   4170 C CD  . ARG B 2 106 ? 18.83300 37.12300 52.63100  1.000 126.29000 ?  106  ARG C    CD  1 
ATOM   4171 N NE  . ARG B 2 106 ? 19.48500 36.00700 53.30000  1.000 130.17000 ?  106  ARG C    NE  1 
ATOM   4172 C CZ  . ARG B 2 106 ? 19.06400 34.74900 53.25600  1.000 119.50000 ?  106  ARG C    CZ  1 
ATOM   4173 N NH1 . ARG B 2 106 ? 17.86800 34.46800 52.77000  1.000 105.17000 ?  106  ARG C    NH1 1 
ATOM   4174 N NH2 . ARG B 2 106 ? 19.83600 33.77600 53.70900  1.000 118.90000 ?  106  ARG C    NH2 1 
ATOM   4175 N N   . ALA B 2 107 ? 21.70800 36.26400 48.02600  1.000 111.05000 ?  107  ALA C    N   1 
ATOM   4176 C CA  . ALA B 2 107 ? 22.99100 35.88000 47.39900  1.000 99.24000  ?  107  ALA C    CA  1 
ATOM   4177 C C   . ALA B 2 107 ? 22.70500 35.04300 46.15400  1.000 92.60000  ?  107  ALA C    C   1 
ATOM   4178 O O   . ALA B 2 107 ? 21.63100 34.42100 46.09900  1.000 92.92000  ?  107  ALA C    O   1 
ATOM   4179 C CB  . ALA B 2 107 ? 23.82400 35.12400 48.39100  1.000 101.80000 ?  107  ALA C    CB  1 
ATOM   4180 N N   . PRO B 2 108 ? 23.62200 34.96500 45.17200  1.000 83.98000  ?  108  PRO C    N   1 
ATOM   4181 C CA  . PRO B 2 108 ? 23.32500 34.26600 43.92400  1.000 86.81000  ?  108  PRO C    CA  1 
ATOM   4182 C C   . PRO B 2 108 ? 22.97800 32.79000 44.14900  1.000 86.94000  ?  108  PRO C    C   1 
ATOM   4183 O O   . PRO B 2 108 ? 22.56300 32.15200 43.21000  1.000 89.91000  ?  108  PRO C    O   1 
ATOM   4184 C CB  . PRO B 2 108 ? 24.64300 34.38100 43.15000  1.000 83.89000  ?  108  PRO C    CB  1 
ATOM   4185 C CG  . PRO B 2 108 ? 25.33100 35.58700 43.74400  1.000 85.32000  ?  108  PRO C    CG  1 
ATOM   4186 C CD  . PRO B 2 108 ? 24.96400 35.54100 45.21000  1.000 79.13000  ?  108  PRO C    CD  1 
ATOM   4187 N N   . TRP B 2 109 ? 23.13900 32.29400 45.37400  1.000 85.48000  ?  109  TRP C    N   1 
ATOM   4188 C CA  . TRP B 2 109 ? 22.91900 30.85300 45.65500  1.000 86.62000  ?  109  TRP C    CA  1 
ATOM   4189 C C   . TRP B 2 109 ? 21.73300 30.66800 46.59700  1.000 86.80000  ?  109  TRP C    C   1 
ATOM   4190 O O   . TRP B 2 109 ? 21.51000 29.53000 47.03700  1.000 81.23000  ?  109  TRP C    O   1 
ATOM   4191 C CB  . TRP B 2 109 ? 24.19400 30.27500 46.26500  1.000 84.65000  ?  109  TRP C    CB  1 
ATOM   4192 C CG  . TRP B 2 109 ? 24.64500 30.99900 47.49400  1.000 83.74000  ?  109  TRP C    CG  1 
ATOM   4193 C CD1 . TRP B 2 109 ? 24.05200 30.98800 48.72200  1.000 85.65000  ?  109  TRP C    CD1 1 
ATOM   4194 C CD2 . TRP B 2 109 ? 25.77200 31.88400 47.60100  1.000 81.35000  ?  109  TRP C    CD2 1 
ATOM   4195 N NE1 . TRP B 2 109 ? 24.74500 31.78600 49.59000  1.000 82.45000  ?  109  TRP C    NE1 1 
ATOM   4196 C CE2 . TRP B 2 109 ? 25.80400 32.35000 48.93100  1.000 79.46000  ?  109  TRP C    CE2 1 
ATOM   4197 C CE3 . TRP B 2 109 ? 26.75700 32.31900 46.71000  1.000 80.38000  ?  109  TRP C    CE3 1 
ATOM   4198 C CZ2 . TRP B 2 109 ? 26.78300 33.22900 49.38700  1.000 77.17000  ?  109  TRP C    CZ2 1 
ATOM   4199 C CZ3 . TRP B 2 109 ? 27.72500 33.18700 47.16100  1.000 82.96000  ?  109  TRP C    CZ3 1 
ATOM   4200 C CH2 . TRP B 2 109 ? 27.73500 33.63500 48.48100  1.000 79.00000  ?  109  TRP C    CH2 1 
ATOM   4201 N N   . ALA B 2 110 ? 21.00600 31.74300 46.88900  1.000 87.67000  ?  110  ALA C    N   1 
ATOM   4202 C CA  . ALA B 2 110 ? 19.90100 31.66900 47.84000  1.000 97.02000  ?  110  ALA C    CA  1 
ATOM   4203 C C   . ALA B 2 110 ? 18.59800 31.38500 47.11600  1.000 109.23000 ?  110  ALA C    C   1 
ATOM   4204 O O   . ALA B 2 110 ? 18.35100 31.91200 46.02600  1.000 107.20000 ?  110  ALA C    O   1 
ATOM   4205 C CB  . ALA B 2 110 ? 19.75200 32.96200 48.64800  1.000 99.59000  ?  110  ALA C    CB  1 
ATOM   4206 N N   . THR B 2 111 ? 17.76100 30.55800 47.73400  1.000 110.40000 ?  111  THR C    N   1 
ATOM   4207 C CA  . THR B 2 111 ? 16.46300 30.27800 47.14700  1.000 112.29000 ?  111  THR C    CA  1 
ATOM   4208 C C   . THR B 2 111 ? 15.65600 31.57400 47.07100  1.000 111.22000 ?  111  THR C    C   1 
ATOM   4209 O O   . THR B 2 111 ? 15.69400 32.38500 48.00200  1.000 112.56000 ?  111  THR C    O   1 
ATOM   4210 C CB  . THR B 2 111 ? 15.73500 29.22100 47.97300  1.000 110.00000 ?  111  THR C    CB  1 
ATOM   4211 O OG1 . THR B 2 111 ? 15.36700 29.78000 49.23300  1.000 116.01000 ?  111  THR C    OG1 1 
ATOM   4212 C CG2 . THR B 2 111 ? 16.68100 28.05200 48.23200  1.000 107.95000 ?  111  THR C    CG2 1 
ATOM   4213 N N   . PRO B 2 112 ? 14.96600 31.83300 45.95900  1.000 118.89000 ?  112  PRO C    N   1 
ATOM   4214 C CA  . PRO B 2 112 ? 14.25700 33.11400 45.81600  1.000 122.45000 ?  112  PRO C    CA  1 
ATOM   4215 C C   . PRO B 2 112 ? 13.00900 33.20100 46.68800  1.000 124.71000 ?  112  PRO C    C   1 
ATOM   4216 O O   . PRO B 2 112 ? 12.69800 32.26600 47.43500  1.000 124.83000 ?  112  PRO C    O   1 
ATOM   4217 C CB  . PRO B 2 112 ? 13.88900 33.15500 44.32300  1.000 123.36000 ?  112  PRO C    CB  1 
ATOM   4218 C CG  . PRO B 2 112 ? 14.73300 32.09800 43.65600  1.000 120.27000 ?  112  PRO C    CG  1 
ATOM   4219 C CD  . PRO B 2 112 ? 14.94000 31.04500 44.71300  1.000 119.26000 ?  112  PRO C    CD  1 
ATOM   4220 N N   . ASN B 2 113 ? 12.29200 34.33100 46.61000  1.000 125.26000 ?  113  ASN C    N   1 
ATOM   4221 C CA  . ASN B 2 113 ? 10.94100 34.48800 47.17600  1.000 127.19000 ?  113  ASN C    CA  1 
ATOM   4222 C C   . ASN B 2 113 ? 10.15400 35.18200 46.06100  1.000 128.97000 ?  113  ASN C    C   1 
ATOM   4223 O O   . ASN B 2 113 ? 10.21100 36.40900 45.93500  1.000 127.89000 ?  113  ASN C    O   1 
ATOM   4224 C CB  . ASN B 2 113 ? 10.93700 35.29800 48.47600  1.000 125.24000 ?  113  ASN C    CB  1 
ATOM   4225 C CG  . ASN B 2 113 ? 11.58100 34.57600 49.64500  1.000 124.18000 ?  113  ASN C    CG  1 
ATOM   4226 O OD1 . ASN B 2 113 ? 12.65000 34.97500 50.11900  1.000 126.24000 ?  113  ASN C    OD1 1 
ATOM   4227 N ND2 . ASN B 2 113 ? 10.91500 33.53800 50.14600  1.000 123.40000 ?  113  ASN C    ND2 1 
ATOM   4228 N N   . ASN B 2 114 ? 9.42200  34.41100 45.25000  1.000 129.52000 ?  114  ASN C    N   1 
ATOM   4229 C CA  . ASN B 2 114 ? 8.66000  35.04900 44.18300  1.000 130.89000 ?  114  ASN C    CA  1 
ATOM   4230 C C   . ASN B 2 114 ? 7.35600  35.62400 44.72400  1.000 130.39000 ?  114  ASN C    C   1 
ATOM   4231 O O   . ASN B 2 114 ? 6.69100  35.03200 45.58100  1.000 126.40000 ?  114  ASN C    O   1 
ATOM   4232 C CB  . ASN B 2 114 ? 8.39300  34.11700 42.98300  1.000 131.30000 ?  114  ASN C    CB  1 
ATOM   4233 C CG  . ASN B 2 114 ? 7.68400  32.82600 43.34500  1.000 130.00000 ?  114  ASN C    CG  1 
ATOM   4234 O OD1 . ASN B 2 114 ? 7.22400  32.64300 44.46500  1.000 137.14000 ?  114  ASN C    OD1 1 
ATOM   4235 N ND2 . ASN B 2 114 ? 7.54000  31.94300 42.36100  1.000 128.48000 ?  114  ASN C    ND2 1 
ATOM   4236 N N   . TYR B 2 115 ? 7.03600  36.82100 44.24400  1.000 134.91000 ?  115  TYR C    N   1 
ATOM   4237 C CA  . TYR B 2 115 ? 5.80300  37.52800 44.54800  1.000 134.01000 ?  115  TYR C    CA  1 
ATOM   4238 C C   . TYR B 2 115 ? 5.11600  37.86700 43.23200  1.000 134.90000 ?  115  TYR C    C   1 
ATOM   4239 O O   . TYR B 2 115 ? 5.76700  38.36900 42.31000  1.000 137.33000 ?  115  TYR C    O   1 
ATOM   4240 C CB  . TYR B 2 115 ? 6.07500  38.82000 45.32700  1.000 131.65000 ?  115  TYR C    CB  1 
ATOM   4241 C CG  . TYR B 2 115 ? 6.97800  38.73500 46.53300  1.000 128.87000 ?  115  TYR C    CG  1 
ATOM   4242 C CD1 . TYR B 2 115 ? 6.46300  38.41500 47.78100  1.000 132.62000 ?  115  TYR C    CD1 1 
ATOM   4243 C CD2 . TYR B 2 115 ? 8.32900  39.02400 46.44000  1.000 124.94000 ?  115  TYR C    CD2 1 
ATOM   4244 C CE1 . TYR B 2 115 ? 7.26900  38.36000 48.90300  1.000 133.05000 ?  115  TYR C    CE1 1 
ATOM   4245 C CE2 . TYR B 2 115 ? 9.14100  38.97900 47.56600  1.000 131.53000 ?  115  TYR C    CE2 1 
ATOM   4246 C CZ  . TYR B 2 115 ? 8.60700  38.64700 48.79800  1.000 133.55000 ?  115  TYR C    CZ  1 
ATOM   4247 O OH  . TYR B 2 115 ? 9.40500  38.59800 49.92600  1.000 128.62000 ?  115  TYR C    OH  1 
ATOM   4248 N N   . TRP B 2 116 ? 3.81500  37.60100 43.14100  1.000 136.89000 ?  116  TRP C    N   1 
ATOM   4249 C CA  . TRP B 2 116 ? 3.04800  37.94300 41.95100  1.000 137.93000 ?  116  TRP C    CA  1 
ATOM   4250 C C   . TRP B 2 116 ? 2.24900  39.22900 42.17200  1.000 139.90000 ?  116  TRP C    C   1 
ATOM   4251 O O   . TRP B 2 116 ? 2.27600  39.84000 43.24300  1.000 136.65000 ?  116  TRP C    O   1 
ATOM   4252 C CB  . TRP B 2 116 ? 2.15100  36.77900 41.52400  1.000 132.53000 ?  116  TRP C    CB  1 
ATOM   4253 C CG  . TRP B 2 116 ? 2.92200  35.51900 41.34000  1.000 133.03000 ?  116  TRP C    CG  1 
ATOM   4254 C CD1 . TRP B 2 116 ? 3.35100  34.65800 42.31300  1.000 131.28000 ?  116  TRP C    CD1 1 
ATOM   4255 C CD2 . TRP B 2 116 ? 3.39800  34.99200 40.09800  1.000 137.10000 ?  116  TRP C    CD2 1 
ATOM   4256 N NE1 . TRP B 2 116 ? 4.05000  33.61600 41.75000  1.000 131.48000 ?  116  TRP C    NE1 1 
ATOM   4257 C CE2 . TRP B 2 116 ? 4.09500  33.79800 40.39100  1.000 139.93000 ?  116  TRP C    CE2 1 
ATOM   4258 C CE3 . TRP B 2 116 ? 3.29400  35.40700 38.76500  1.000 133.17000 ?  116  TRP C    CE3 1 
ATOM   4259 C CZ2 . TRP B 2 116 ? 4.68400  33.01300 39.39600  1.000 138.19000 ?  116  TRP C    CZ2 1 
ATOM   4260 C CZ3 . TRP B 2 116 ? 3.87800  34.63100 37.78400  1.000 136.53000 ?  116  TRP C    CZ3 1 
ATOM   4261 C CH2 . TRP B 2 116 ? 4.56500  33.44600 38.10300  1.000 138.84000 ?  116  TRP C    CH2 1 
ATOM   4262 N N   . GLY B 2 117 ? 1.55200  39.65800 41.13000  1.000 140.20000 ?  117  GLY C    N   1 
ATOM   4263 C CA  . GLY B 2 117 ? 0.79200  40.89700 41.15500  1.000 135.53000 ?  117  GLY C    CA  1 
ATOM   4264 C C   . GLY B 2 117 ? -0.66100 40.66500 41.49700  1.000 130.69000 ?  117  GLY C    C   1 
ATOM   4265 O O   . GLY B 2 117 ? -0.99600 39.82100 42.33500  1.000 125.92000 ?  117  GLY C    O   1 
ATOM   4266 N N   . GLN B 2 118 ? -1.53100 41.43000 40.85100  1.000 129.72000 ?  118  GLN C    N   1 
ATOM   4267 C CA  . GLN B 2 118 ? -2.97100 41.21900 40.91400  1.000 127.45000 ?  118  GLN C    CA  1 
ATOM   4268 C C   . GLN B 2 118 ? -3.54900 40.72700 39.59700  1.000 128.19000 ?  118  GLN C    C   1 
ATOM   4269 O O   . GLN B 2 118 ? -4.38900 39.82700 39.58800  1.000 121.84000 ?  118  GLN C    O   1 
ATOM   4270 C CB  . GLN B 2 118 ? -3.67000 42.51900 41.32600  1.000 126.90000 ?  118  GLN C    CB  1 
ATOM   4271 C CG  . GLN B 2 118 ? -5.12100 42.37200 41.79600  1.000 118.05000 ?  118  GLN C    CG  1 
ATOM   4272 C CD  . GLN B 2 118 ? -5.82100 43.72500 41.91400  1.000 111.33000 ?  118  GLN C    CD  1 
ATOM   4273 O OE1 . GLN B 2 118 ? -5.44700 44.55400 42.74200  1.000 109.17000 ?  118  GLN C    OE1 1 
ATOM   4274 N NE2 . GLN B 2 118 ? -6.79800 43.97500 41.03500  1.000 105.19000 ?  118  GLN C    NE2 1 
ATOM   4275 N N   . GLY B 2 119 ? -3.09100 41.27900 38.48000  1.000 134.01000 ?  119  GLY C    N   1 
ATOM   4276 C CA  . GLY B 2 119 ? -3.64200 40.96000 37.18000  1.000 137.10000 ?  119  GLY C    CA  1 
ATOM   4277 C C   . GLY B 2 119 ? -3.91100 42.22800 36.39500  1.000 139.67000 ?  119  GLY C    C   1 
ATOM   4278 O O   . GLY B 2 119 ? -4.37700 43.22000 36.96100  1.000 141.83000 ?  119  GLY C    O   1 
ATOM   4279 N N   . THR B 2 120 ? -3.60100 42.23700 35.10700  1.000 137.41000 ?  120  THR C    N   1 
ATOM   4280 C CA  . THR B 2 120 ? -3.88500 43.41600 34.31400  1.000 139.52000 ?  120  THR C    CA  1 
ATOM   4281 C C   . THR B 2 120 ? -4.23100 42.97200 32.89900  1.000 148.30000 ?  120  THR C    C   1 
ATOM   4282 O O   . THR B 2 120 ? -3.61600 43.38600 31.91900  1.000 154.13000 ?  120  THR C    O   1 
ATOM   4283 C CB  . THR B 2 120 ? -2.71100 44.40000 34.31700  1.000 140.39000 ?  120  THR C    CB  1 
ATOM   4284 O OG1 . THR B 2 120 ? -2.16300 44.51500 35.63200  1.000 144.01000 ?  120  THR C    OG1 1 
ATOM   4285 C CG2 . THR B 2 120 ? -3.18500 45.76300 33.88800  1.000 139.60000 ?  120  THR C    CG2 1 
ATOM   4286 N N   . GLN B 2 121 ? -5.24000 42.11100 32.77100  1.000 148.78000 ?  121  GLN C    N   1 
ATOM   4287 C CA  . GLN B 2 121 ? -5.66400 41.68200 31.44400  1.000 149.74000 ?  121  GLN C    CA  1 
ATOM   4288 C C   . GLN B 2 121 ? -6.15200 42.87600 30.63000  1.000 147.91000 ?  121  GLN C    C   1 
ATOM   4289 O O   . GLN B 2 121 ? -6.77800 43.80200 31.16100  1.000 144.19000 ?  121  GLN C    O   1 
ATOM   4290 C CB  . GLN B 2 121 ? -6.76600 40.62700 31.54100  1.000 148.77000 ?  121  GLN C    CB  1 
ATOM   4291 C CG  . GLN B 2 121 ? -6.96500 39.84800 30.24900  1.000 145.42000 ?  121  GLN C    CG  1 
ATOM   4292 C CD  . GLN B 2 121 ? -8.30500 39.17700 30.15900  1.000 139.94000 ?  121  GLN C    CD  1 
ATOM   4293 O OE1 . GLN B 2 121 ? -8.39800 37.94800 30.07200  1.000 131.70000 ?  121  GLN C    OE1 1 
ATOM   4294 N NE2 . GLN B 2 121 ? -9.35900 39.97900 30.17600  1.000 136.55000 ?  121  GLN C    NE2 1 
ATOM   4295 N N   . VAL B 2 122 ? -5.83700 42.86100 29.33400  1.000 146.79000 ?  122  VAL C    N   1 
ATOM   4296 C CA  . VAL B 2 122 ? -6.31800 43.89200 28.42000  1.000 151.82000 ?  122  VAL C    CA  1 
ATOM   4297 C C   . VAL B 2 122 ? -6.35600 43.33200 27.00700  1.000 147.77000 ?  122  VAL C    C   1 
ATOM   4298 O O   . VAL B 2 122 ? -5.63000 42.38700 26.67700  1.000 145.72000 ?  122  VAL C    O   1 
ATOM   4299 C CB  . VAL B 2 122 ? -5.45800 45.18000 28.50100  1.000 146.76000 ?  122  VAL C    CB  1 
ATOM   4300 C CG1 . VAL B 2 122 ? -4.15300 45.02300 27.71500  1.000 134.25000 ?  122  VAL C    CG1 1 
ATOM   4301 C CG2 . VAL B 2 122 ? -6.26700 46.33700 27.95000  1.000 140.00000 ?  122  VAL C    CG2 1 
ATOM   4302 N N   . THR B 2 123 ? -7.23600 43.90700 26.17800  1.000 144.06000 ?  123  THR C    N   1 
ATOM   4303 C CA  . THR B 2 123 ? -7.19800 43.74600 24.72000  1.000 145.84000 ?  123  THR C    CA  1 
ATOM   4304 C C   . THR B 2 123 ? -7.96100 44.88800 24.02800  1.000 137.00000 ?  123  THR C    C   1 
ATOM   4305 O O   . THR B 2 123 ? -7.36300 45.79900 23.43600  1.000 127.93000 ?  123  THR C    O   1 
ATOM   4306 C CB  . THR B 2 123 ? -7.78400 42.38900 24.27300  1.000 140.38000 ?  123  THR C    CB  1 
ATOM   4307 O OG1 . THR B 2 123 ? -7.45300 42.14700 22.89300  1.000 135.62000 ?  123  THR C    OG1 1 
ATOM   4308 C CG2 . THR B 2 123 ? -9.29300 42.38900 24.45100  1.000 132.15000 ?  123  THR C    CG2 1 
ATOM   4309 N N   . MET C 3 22  ? 9.31800  50.59700 61.88900  1.000 106.16000 ?  1    MET R    N   1 
ATOM   4310 C CA  . MET C 3 22  ? 10.60300 51.22500 62.20700  1.000 105.69000 ?  1    MET R    CA  1 
ATOM   4311 C C   . MET C 3 22  ? 11.74900 50.85900 61.27400  1.000 109.72000 ?  1    MET R    C   1 
ATOM   4312 O O   . MET C 3 22  ? 11.97600 49.68200 60.98800  1.000 108.54000 ?  1    MET R    O   1 
ATOM   4313 C CB  . MET C 3 22  ? 11.04400 50.87200 63.61300  1.000 103.12000 ?  1    MET R    CB  1 
ATOM   4314 C CG  . MET C 3 22  ? 12.31800 51.58600 63.98100  1.000 103.30000 ?  1    MET R    CG  1 
ATOM   4315 S SD  . MET C 3 22  ? 12.69300 51.48500 65.73500  1.000 117.01000 ?  1    MET R    SD  1 
ATOM   4316 C CE  . MET C 3 22  ? 12.92400 49.71300 65.93900  1.000 111.24000 ?  1    MET R    CE  1 
ATOM   4317 N N   . THR C 3 23  ? 12.49400 51.87500 60.84400  1.000 106.50000 ?  2    THR R    N   1 
ATOM   4318 C CA  . THR C 3 23  ? 13.66600 51.67000 60.00600  1.000 99.97000  ?  2    THR R    CA  1 
ATOM   4319 C C   . THR C 3 23  ? 14.84100 51.12700 60.81500  1.000 103.07000 ?  2    THR R    C   1 
ATOM   4320 O O   . THR C 3 23  ? 15.03000 51.45000 61.99400  1.000 99.41000  ?  2    THR R    O   1 
ATOM   4321 C CB  . THR C 3 23  ? 14.07700 52.97600 59.32500  1.000 98.79000  ?  2    THR R    CB  1 
ATOM   4322 O OG1 . THR C 3 23  ? 12.91700 53.63900 58.81900  1.000 98.16000  ?  2    THR R    OG1 1 
ATOM   4323 C CG2 . THR C 3 23  ? 15.04000 52.72100 58.19100  1.000 97.36000  ?  2    THR R    CG2 1 
ATOM   4324 N N   . GLU C 3 24  ? 15.64900 50.30900 60.14700  1.000 103.01000 ?  3    GLU R    N   1 
ATOM   4325 C CA  . GLU C 3 24  ? 16.82600 49.68300 60.72600  1.000 94.53000  ?  3    GLU R    CA  1 
ATOM   4326 C C   . GLU C 3 24  ? 18.01300 49.94800 59.80900  1.000 95.81000  ?  3    GLU R    C   1 
ATOM   4327 O O   . GLU C 3 24  ? 17.91200 49.76400 58.59200  1.000 101.64000 ?  3    GLU R    O   1 
ATOM   4328 C CB  . GLU C 3 24  ? 16.57700 48.19100 60.89300  1.000 93.88000  ?  3    GLU R    CB  1 
ATOM   4329 C CG  . GLU C 3 24  ? 17.69600 47.41700 61.48900  1.000 97.78000  ?  3    GLU R    CG  1 
ATOM   4330 C CD  . GLU C 3 24  ? 17.35400 45.94400 61.58400  1.000 108.98000 ?  3    GLU R    CD  1 
ATOM   4331 O OE1 . GLU C 3 24  ? 16.43300 45.49800 60.86400  1.000 116.59000 ?  3    GLU R    OE1 1 
ATOM   4332 O OE2 . GLU C 3 24  ? 17.97900 45.23500 62.40000  1.000 107.25000 ?  3    GLU R    OE2 1 
ATOM   4333 N N   . TYR C 3 25  ? 19.11900 50.41200 60.37600  1.000 89.35000  ?  4    TYR R    N   1 
ATOM   4334 C CA  . TYR C 3 25  ? 20.31800 50.72000 59.61000  1.000 85.15000  ?  4    TYR R    CA  1 
ATOM   4335 C C   . TYR C 3 25  ? 21.43800 49.80400 60.06700  1.000 83.02000  ?  4    TYR R    C   1 
ATOM   4336 O O   . TYR C 3 25  ? 21.74300 49.75200 61.26200  1.000 80.73000  ?  4    TYR R    O   1 
ATOM   4337 C CB  . TYR C 3 25  ? 20.75300 52.16400 59.80100  1.000 82.34000  ?  4    TYR R    CB  1 
ATOM   4338 C CG  . TYR C 3 25  ? 19.73300 53.19200 59.41500  1.000 88.59000  ?  4    TYR R    CG  1 
ATOM   4339 C CD1 . TYR C 3 25  ? 19.46400 53.46500 58.09300  1.000 90.82000  ?  4    TYR R    CD1 1 
ATOM   4340 C CD2 . TYR C 3 25  ? 19.04500 53.90600 60.38100  1.000 95.12000  ?  4    TYR R    CD2 1 
ATOM   4341 C CE1 . TYR C 3 25  ? 18.54000 54.42900 57.73800  1.000 93.75000  ?  4    TYR R    CE1 1 
ATOM   4342 C CE2 . TYR C 3 25  ? 18.10900 54.86300 60.03400  1.000 96.70000  ?  4    TYR R    CE2 1 
ATOM   4343 C CZ  . TYR C 3 25  ? 17.86300 55.12100 58.70800  1.000 93.80000  ?  4    TYR R    CZ  1 
ATOM   4344 O OH  . TYR C 3 25  ? 16.94200 56.07900 58.34900  1.000 94.63000  ?  4    TYR R    OH  1 
ATOM   4345 N N   . LYS C 3 26  ? 22.06200 49.10600 59.12500  1.000 77.77000  ?  5    LYS R    N   1 
ATOM   4346 C CA  . LYS C 3 26  ? 23.17200 48.22100 59.43500  1.000 74.74000  ?  5    LYS R    CA  1 
ATOM   4347 C C   . LYS C 3 26  ? 24.46500 48.93400 59.08800  1.000 75.95000  ?  5    LYS R    C   1 
ATOM   4348 O O   . LYS C 3 26  ? 24.70400 49.25200 57.91900  1.000 75.67000  ?  5    LYS R    O   1 
ATOM   4349 C CB  . LYS C 3 26  ? 23.03000 46.89900 58.69700  1.000 72.40000  ?  5    LYS R    CB  1 
ATOM   4350 C CG  . LYS C 3 26  ? 21.72100 46.25300 59.05500  1.000 83.67000  ?  5    LYS R    CG  1 
ATOM   4351 C CD  . LYS C 3 26  ? 21.50300 44.88700 58.46100  1.000 87.19000  ?  5    LYS R    CD  1 
ATOM   4352 C CE  . LYS C 3 26  ? 20.13500 44.38000 58.90700  1.000 102.65000 ?  5    LYS R    CE  1 
ATOM   4353 N NZ  . LYS C 3 26  ? 19.79800 43.01600 58.41000  1.000 119.97000 ?  5    LYS R    NZ  1 
ATOM   4354 N N   . LEU C 3 27  ? 25.27700 49.20700 60.11400  1.000 73.20000  ?  6    LEU R    N   1 
ATOM   4355 C CA  . LEU C 3 27  ? 26.50000 49.99100 60.00100  1.000 69.42000  ?  6    LEU R    CA  1 
ATOM   4356 C C   . LEU C 3 27  ? 27.72000 49.10600 60.23900  1.000 71.68000  ?  6    LEU R    C   1 
ATOM   4357 O O   . LEU C 3 27  ? 27.70800 48.24200 61.12500  1.000 71.16000  ?  6    LEU R    O   1 
ATOM   4358 C CB  . LEU C 3 27  ? 26.48400 51.14000 61.00300  1.000 68.90000  ?  6    LEU R    CB  1 
ATOM   4359 C CG  . LEU C 3 27  ? 25.21000 51.97200 61.12000  1.000 73.63000  ?  6    LEU R    CG  1 
ATOM   4360 C CD1 . LEU C 3 27  ? 25.30100 52.93700 62.28000  1.000 69.61000  ?  6    LEU R    CD1 1 
ATOM   4361 C CD2 . LEU C 3 27  ? 25.02500 52.74600 59.83800  1.000 76.20000  ?  6    LEU R    CD2 1 
ATOM   4362 N N   . VAL C 3 28  ? 28.77300 49.30200 59.44200  1.000 66.49000  ?  7    VAL R    N   1 
ATOM   4363 C CA  . VAL C 3 28  ? 29.98200 48.49400 59.56600  1.000 68.45000  ?  7    VAL R    CA  1 
ATOM   4364 C C   . VAL C 3 28  ? 31.15000 49.41000 59.90100  1.000 66.09000  ?  7    VAL R    C   1 
ATOM   4365 O O   . VAL C 3 28  ? 31.37900 50.41300 59.21900  1.000 64.67000  ?  7    VAL R    O   1 
ATOM   4366 C CB  . VAL C 3 28  ? 30.28500 47.68600 58.29100  1.000 69.22000  ?  7    VAL R    CB  1 
ATOM   4367 C CG1 . VAL C 3 28  ? 31.61900 46.97500 58.44800  1.000 66.69000  ?  7    VAL R    CG1 1 
ATOM   4368 C CG2 . VAL C 3 28  ? 29.17800 46.68400 57.97500  1.000 68.10000  ?  7    VAL R    CG2 1 
ATOM   4369 N N   . VAL C 3 29  ? 31.88000 49.07200 60.95300  1.000 66.49000  ?  8    VAL R    N   1 
ATOM   4370 C CA  . VAL C 3 29  ? 33.03600 49.84800 61.38300  1.000 65.15000  ?  8    VAL R    CA  1 
ATOM   4371 C C   . VAL C 3 29  ? 34.27300 49.16900 60.82400  1.000 69.64000  ?  8    VAL R    C   1 
ATOM   4372 O O   . VAL C 3 29  ? 34.62900 48.05900 61.24300  1.000 77.41000  ?  8    VAL R    O   1 
ATOM   4373 C CB  . VAL C 3 29  ? 33.11400 49.97000 62.90900  1.000 60.55000  ?  8    VAL R    CB  1 
ATOM   4374 C CG1 . VAL C 3 29  ? 34.02300 51.09000 63.25900  1.000 60.27000  ?  8    VAL R    CG1 1 
ATOM   4375 C CG2 . VAL C 3 29  ? 31.76000 50.22800 63.46200  1.000 59.36000  ?  8    VAL R    CG2 1 
ATOM   4376 N N   . VAL C 3 30  ? 34.93700 49.82400 59.88400  1.000 62.61000  ?  9    VAL R    N   1 
ATOM   4377 C CA  . VAL C 3 30  ? 36.18000 49.29700 59.35800  1.000 62.44000  ?  9    VAL R    CA  1 
ATOM   4378 C C   . VAL C 3 30  ? 37.30400 50.24300 59.73700  1.000 62.10000  ?  9    VAL R    C   1 
ATOM   4379 O O   . VAL C 3 30  ? 37.09100 51.44200 59.96500  1.000 57.12000  ?  9    VAL R    O   1 
ATOM   4380 C CB  . VAL C 3 30  ? 36.12000 49.08200 57.83800  1.000 62.83000  ?  9    VAL R    CB  1 
ATOM   4381 C CG1 . VAL C 3 30  ? 34.94600 48.20100 57.50300  1.000 63.56000  ?  9    VAL R    CG1 1 
ATOM   4382 C CG2 . VAL C 3 30  ? 36.05700 50.41800 57.11400  1.000 58.99000  ?  9    VAL R    CG2 1 
ATOM   4383 N N   . GLY C 3 31  ? 38.50500 49.67900 59.82200  1.000 58.17000  ?  10   GLY R    N   1 
ATOM   4384 C CA  . GLY C 3 31  ? 39.68900 50.44000 60.14300  1.000 57.85000  ?  10   GLY R    CA  1 
ATOM   4385 C C   . GLY C 3 31  ? 40.83000 49.49600 60.40200  1.000 57.92000  ?  10   GLY R    C   1 
ATOM   4386 O O   . GLY C 3 31  ? 40.65900 48.27500 60.43000  1.000 61.15000  ?  10   GLY R    O   1 
ATOM   4387 N N   . ALA C 3 32  ? 42.01200 50.08700 60.58900  1.000 56.74000  ?  11   ALA R    N   1 
ATOM   4388 C CA  . ALA C 3 32  ? 43.18100 49.31800 60.97100  1.000 51.38000  ?  11   ALA R    CA  1 
ATOM   4389 C C   . ALA C 3 32  ? 43.07700 48.87500 62.42200  1.000 65.39000  ?  11   ALA R    C   1 
ATOM   4390 O O   . ALA C 3 32  ? 42.25900 49.36900 63.21100  1.000 68.88000  ?  11   ALA R    O   1 
ATOM   4391 C CB  . ALA C 3 32  ? 44.44600 50.13000 60.79400  1.000 50.82000  ?  11   ALA R    CB  1 
ATOM   4392 N N   . VAL C 3 33  ? 43.93500 47.92900 62.78500  1.000 67.95000  ?  12   VAL R    N   1 
ATOM   4393 C CA  . VAL C 3 33  ? 43.90000 47.40800 64.14200  1.000 70.08000  ?  12   VAL R    CA  1 
ATOM   4394 C C   . VAL C 3 33  ? 44.41600 48.47800 65.10300  1.000 67.79000  ?  12   VAL R    C   1 
ATOM   4395 O O   . VAL C 3 33  ? 45.32400 49.25300 64.78000  1.000 64.41000  ?  12   VAL R    O   1 
ATOM   4396 C CB  . VAL C 3 33  ? 44.69400 46.08700 64.22300  1.000 62.32000  ?  12   VAL R    CB  1 
ATOM   4397 C CG1 . VAL C 3 33  ? 46.16100 46.32500 64.22700  1.000 61.73000  ?  12   VAL R    CG1 1 
ATOM   4398 C CG2 . VAL C 3 33  ? 44.31200 45.31900 65.45200  1.000 67.36000  ?  12   VAL R    CG2 1 
ATOM   4399 N N   . GLY C 3 34  ? 43.79000 48.57400 66.27000  1.000 73.07000  ?  13   GLY R    N   1 
ATOM   4400 C CA  . GLY C 3 34  ? 44.30300 49.46700 67.29200  1.000 72.68000  ?  13   GLY R    CA  1 
ATOM   4401 C C   . GLY C 3 34  ? 43.99900 50.92500 67.07700  1.000 73.06000  ?  13   GLY R    C   1 
ATOM   4402 O O   . GLY C 3 34  ? 44.71400 51.78300 67.60300  1.000 79.83000  ?  13   GLY R    O   1 
ATOM   4403 N N   . VAL C 3 35  ? 42.97200 51.24000 66.29100  1.000 70.01000  ?  14   VAL R    N   1 
ATOM   4404 C CA  . VAL C 3 35  ? 42.49000 52.61100 66.22900  1.000 69.82000  ?  14   VAL R    CA  1 
ATOM   4405 C C   . VAL C 3 35  ? 41.33000 52.81200 67.18100  1.000 67.57000  ?  14   VAL R    C   1 
ATOM   4406 O O   . VAL C 3 35  ? 40.92700 53.95800 67.42200  1.000 67.20000  ?  14   VAL R    O   1 
ATOM   4407 C CB  . VAL C 3 35  ? 42.08800 52.99400 64.78700  1.000 69.76000  ?  14   VAL R    CB  1 
ATOM   4408 C CG1 . VAL C 3 35  ? 43.24500 52.79500 63.85400  1.000 67.40000  ?  14   VAL R    CG1 1 
ATOM   4409 C CG2 . VAL C 3 35  ? 40.90100 52.17100 64.30300  1.000 67.86000  ?  14   VAL R    CG2 1 
ATOM   4410 N N   . GLY C 3 36  ? 40.78000 51.73700 67.72900  1.000 69.17000  ?  15   GLY R    N   1 
ATOM   4411 C CA  . GLY C 3 36  ? 39.72000 51.85700 68.70600  1.000 77.77000  ?  15   GLY R    CA  1 
ATOM   4412 C C   . GLY C 3 36  ? 38.33900 51.84500 68.09200  1.000 77.51000  ?  15   GLY R    C   1 
ATOM   4413 O O   . GLY C 3 36  ? 37.44700 52.59400 68.51700  1.000 74.99000  ?  15   GLY R    O   1 
ATOM   4414 N N   . LYS C 3 37  ? 38.15500 50.97400 67.10500  1.000 74.45000  ?  16   LYS R    N   1 
ATOM   4415 C CA  . LYS C 3 37  ? 36.82400 50.84400 66.47100  1.000 74.20000  ?  16   LYS R    CA  1 
ATOM   4416 C C   . LYS C 3 37  ? 35.90600 50.12400 67.45800  1.000 73.17000  ?  16   LYS R    C   1 
ATOM   4417 O O   . LYS C 3 37  ? 34.71700 50.46900 67.50900  1.000 73.15000  ?  16   LYS R    O   1 
ATOM   4418 C CB  . LYS C 3 37  ? 36.94800 50.11100 65.13400  1.000 75.40000  ?  16   LYS R    CB  1 
ATOM   4419 C CG  . LYS C 3 37  ? 38.25000 49.36100 64.90600  1.000 72.79000  ?  16   LYS R    CG  1 
ATOM   4420 C CD  . LYS C 3 37  ? 38.24300 48.57700 63.61600  1.000 60.13000  ?  16   LYS R    CD  1 
ATOM   4421 C CE  . LYS C 3 37  ? 39.50900 47.77700 63.40500  1.000 57.10000  ?  16   LYS R    CE  1 
ATOM   4422 N NZ  . LYS C 3 37  ? 39.37500 46.84400 62.26200  1.000 68.34000  ?  16   LYS R    NZ  1 
ATOM   4423 N N   . SER C 3 38  ? 36.44400 49.17200 68.21900  1.000 75.48000  ?  17   SER R    N   1 
ATOM   4424 C CA  . SER C 3 38  ? 35.62600 48.51100 69.23800  1.000 77.34000  ?  17   SER R    CA  1 
ATOM   4425 C C   . SER C 3 38  ? 35.29900 49.46900 70.37300  1.000 74.22000  ?  17   SER R    C   1 
ATOM   4426 O O   . SER C 3 38  ? 34.19000 49.43700 70.91400  1.000 75.52000  ?  17   SER R    O   1 
ATOM   4427 C CB  . SER C 3 38  ? 36.31700 47.25800 69.78100  1.000 71.08000  ?  17   SER R    CB  1 
ATOM   4428 O OG  . SER C 3 38  ? 37.52400 47.61100 70.42200  1.000 81.40000  ?  17   SER R    OG  1 
ATOM   4429 N N   . ALA C 3 39  ? 36.24600 50.34000 70.73100  1.000 74.89000  ?  18   ALA R    N   1 
ATOM   4430 C CA  . ALA C 3 39  ? 35.98600 51.35200 71.75100  1.000 70.74000  ?  18   ALA R    CA  1 
ATOM   4431 C C   . ALA C 3 39  ? 34.84200 52.26500 71.34300  1.000 71.45000  ?  18   ALA R    C   1 
ATOM   4432 O O   . ALA C 3 39  ? 33.98200 52.60200 72.16100  1.000 73.48000  ?  18   ALA R    O   1 
ATOM   4433 C CB  . ALA C 3 39  ? 37.24200 52.17800 71.98800  1.000 74.47000  ?  18   ALA R    CB  1 
ATOM   4434 N N   . LEU C 3 40  ? 34.83000 52.67800 70.07800  1.000 74.78000  ?  19   LEU R    N   1 
ATOM   4435 C CA  . LEU C 3 40  ? 33.79000 53.54500 69.53100  1.000 72.13000  ?  19   LEU R    CA  1 
ATOM   4436 C C   . LEU C 3 40  ? 32.40000 52.92700 69.59600  1.000 73.44000  ?  19   LEU R    C   1 
ATOM   4437 O O   . LEU C 3 40  ? 31.41000 53.65800 69.71800  1.000 74.06000  ?  19   LEU R    O   1 
ATOM   4438 C CB  . LEU C 3 40  ? 34.12100 53.86900 68.08200  1.000 65.94000  ?  19   LEU R    CB  1 
ATOM   4439 C CG  . LEU C 3 40  ? 34.75500 55.18600 67.73200  1.000 62.34000  ?  19   LEU R    CG  1 
ATOM   4440 C CD1 . LEU C 3 40  ? 35.00700 55.10600 66.28200  1.000 73.80000  ?  19   LEU R    CD1 1 
ATOM   4441 C CD2 . LEU C 3 40  ? 33.73900 56.24500 67.96100  1.000 61.63000  ?  19   LEU R    CD2 1 
ATOM   4442 N N   . THR C 3 41  ? 32.28900 51.60700 69.45600  1.000 72.16000  ?  20   THR R    N   1 
ATOM   4443 C CA  . THR C 3 41  ? 30.96000 51.01800 69.38400  1.000 71.48000  ?  20   THR R    CA  1 
ATOM   4444 C C   . THR C 3 41  ? 30.37500 50.86300 70.77100  1.000 68.85000  ?  20   THR R    C   1 
ATOM   4445 O O   . THR C 3 41  ? 29.24000 51.26100 71.02700  1.000 72.75000  ?  20   THR R    O   1 
ATOM   4446 C CB  . THR C 3 41  ? 31.00100 49.66500 68.67500  1.000 75.29000  ?  20   THR R    CB  1 
ATOM   4447 O OG1 . THR C 3 41  ? 31.76700 49.77600 67.46800  1.000 68.81000  ?  20   THR R    OG1 1 
ATOM   4448 C CG2 . THR C 3 41  ? 29.56500 49.21800 68.34400  1.000 70.36000  ?  20   THR R    CG2 1 
ATOM   4449 N N   . ILE C 3 42  ? 31.13800 50.27400 71.67000  1.000 73.78000  ?  21   ILE R    N   1 
ATOM   4450 C CA  . ILE C 3 42  ? 30.80300 50.20300 73.08400  1.000 76.74000  ?  21   ILE R    CA  1 
ATOM   4451 C C   . ILE C 3 42  ? 30.27800 51.55200 73.56100  1.000 78.49000  ?  21   ILE R    C   1 
ATOM   4452 O O   . ILE C 3 42  ? 29.17300 51.64100 74.10200  1.000 85.37000  ?  21   ILE R    O   1 
ATOM   4453 C CB  . ILE C 3 42  ? 32.03800 49.74700 73.87300  1.000 71.80000  ?  21   ILE R    CB  1 
ATOM   4454 C CG1 . ILE C 3 42  ? 32.37900 48.32500 73.45400  1.000 69.26000  ?  21   ILE R    CG1 1 
ATOM   4455 C CG2 . ILE C 3 42  ? 31.79500 49.86900 75.33300  1.000 78.76000  ?  21   ILE R    CG2 1 
ATOM   4456 C CD1 . ILE C 3 42  ? 33.77900 47.94500 73.70500  1.000 74.34000  ?  21   ILE R    CD1 1 
ATOM   4457 N N   . GLN C 3 43  ? 31.03300 52.61800 73.30400  1.000 72.99000  ?  22   GLN R    N   1 
ATOM   4458 C CA  . GLN C 3 43  ? 30.61900 53.94800 73.71600  1.000 72.64000  ?  22   GLN R    CA  1 
ATOM   4459 C C   . GLN C 3 43  ? 29.39900 54.47500 72.98400  1.000 75.06000  ?  22   GLN R    C   1 
ATOM   4460 O O   . GLN C 3 43  ? 28.87800 55.52300 73.36000  1.000 77.51000  ?  22   GLN R    O   1 
ATOM   4461 C CB  . GLN C 3 43  ? 31.76000 54.91100 73.53300  1.000 69.36000  ?  22   GLN R    CB  1 
ATOM   4462 C CG  . GLN C 3 43  ? 32.65200 54.87200 74.71700  1.000 81.74000  ?  22   GLN R    CG  1 
ATOM   4463 C CD  . GLN C 3 43  ? 33.82500 55.80400 74.58700  1.000 89.99000  ?  22   GLN R    CD  1 
ATOM   4464 O OE1 . GLN C 3 43  ? 34.12500 56.31300 73.49700  1.000 91.89000  ?  22   GLN R    OE1 1 
ATOM   4465 N NE2 . GLN C 3 43  ? 34.49600 56.05600 75.70600  1.000 93.79000  ?  22   GLN R    NE2 1 
ATOM   4466 N N   . LEU C 3 44  ? 28.93700 53.81100 71.94400  1.000 78.81000  ?  23   LEU R    N   1 
ATOM   4467 C CA  . LEU C 3 44  ? 27.67400 54.24800 71.37900  1.000 80.14000  ?  23   LEU R    CA  1 
ATOM   4468 C C   . LEU C 3 44  ? 26.51900 53.59500 72.11400  1.000 83.11000  ?  23   LEU R    C   1 
ATOM   4469 O O   . LEU C 3 44  ? 25.51500 54.25200 72.39300  1.000 89.61000  ?  23   LEU R    O   1 
ATOM   4470 C CB  . LEU C 3 44  ? 27.57700 53.90200 69.89400  1.000 75.41000  ?  23   LEU R    CB  1 
ATOM   4471 C CG  . LEU C 3 44  ? 26.26300 54.39200 69.30200  1.000 71.89000  ?  23   LEU R    CG  1 
ATOM   4472 C CD1 . LEU C 3 44  ? 26.21800 55.92200 69.35300  1.000 80.89000  ?  23   LEU R    CD1 1 
ATOM   4473 C CD2 . LEU C 3 44  ? 26.01400 53.86500 67.95200  1.000 70.67000  ?  23   LEU R    CD2 1 
ATOM   4474 N N   . ILE C 3 45  ? 26.67500 52.31800 72.46000  1.000 78.51000  ?  24   ILE R    N   1 
ATOM   4475 C CA  . ILE C 3 45  ? 25.59400 51.54100 73.04900  1.000 83.94000  ?  24   ILE R    CA  1 
ATOM   4476 C C   . ILE C 3 45  ? 25.42400 51.84400 74.53500  1.000 92.22000  ?  24   ILE R    C   1 
ATOM   4477 O O   . ILE C 3 45  ? 24.34200 52.24100 74.98300  1.000 94.96000  ?  24   ILE R    O   1 
ATOM   4478 C CB  . ILE C 3 45  ? 25.83000 50.05200 72.76700  1.000 80.24000  ?  24   ILE R    CB  1 
ATOM   4479 C CG1 . ILE C 3 45  ? 25.56400 49.80600 71.29500  1.000 81.17000  ?  24   ILE R    CG1 1 
ATOM   4480 C CG2 . ILE C 3 45  ? 25.01600 49.17700 73.67100  1.000 99.39000  ?  24   ILE R    CG2 1 
ATOM   4481 C CD1 . ILE C 3 45  ? 26.45200 48.82100 70.70600  1.000 92.16000  ?  24   ILE R    CD1 1 
ATOM   4482 N N   . GLN C 3 46  ? 26.47200 51.63700 75.31300  1.000 91.11000  ?  25   GLN R    N   1 
ATOM   4483 C CA  . GLN C 3 46  ? 26.52000 51.95000 76.74600  1.000 100.60000 ?  25   GLN R    CA  1 
ATOM   4484 C C   . GLN C 3 46  ? 25.81900 53.26400 77.21100  1.000 104.87000 ?  25   GLN R    C   1 
ATOM   4485 O O   . GLN C 3 46  ? 26.25500 54.39200 76.91500  1.000 103.26000 ?  25   GLN R    O   1 
ATOM   4486 C CB  . GLN C 3 46  ? 27.99300 51.97000 77.13000  1.000 102.81000 ?  25   GLN R    CB  1 
ATOM   4487 C CG  . GLN C 3 46  ? 28.46500 50.76800 77.90800  1.000 102.98000 ?  25   GLN R    CG  1 
ATOM   4488 C CD  . GLN C 3 46  ? 29.91800 50.92700 78.34300  1.000 115.01000 ?  25   GLN R    CD  1 
ATOM   4489 O OE1 . GLN C 3 46  ? 30.41100 52.04800 78.51600  1.000 124.64000 ?  25   GLN R    OE1 1 
ATOM   4490 N NE2 . GLN C 3 46  ? 30.60200 49.80100 78.55200  1.000 110.76000 ?  25   GLN R    NE2 1 
ATOM   4491 N N   . GLU C 3 52  ? 29.29200 47.15600 83.67300  1.000 105.59000 ?  31   GLU R    N   1 
ATOM   4492 C CA  . GLU C 3 52  ? 29.77100 45.93300 83.02100  1.000 113.73000 ?  31   GLU R    CA  1 
ATOM   4493 C C   . GLU C 3 52  ? 29.26600 45.75600 81.57600  1.000 115.34000 ?  31   GLU R    C   1 
ATOM   4494 O O   . GLU C 3 52  ? 28.05300 45.81100 81.33300  1.000 121.31000 ?  31   GLU R    O   1 
ATOM   4495 C CB  . GLU C 3 52  ? 29.35600 44.69800 83.82800  1.000 115.08000 ?  31   GLU R    CB  1 
ATOM   4496 C CG  . GLU C 3 52  ? 29.32800 43.41500 82.97300  1.000 116.61000 ?  31   GLU R    CG  1 
ATOM   4497 C CD  . GLU C 3 52  ? 28.77800 42.20000 83.71400  1.000 126.11000 ?  31   GLU R    CD  1 
ATOM   4498 O OE1 . GLU C 3 52  ? 28.71000 42.25100 84.96300  1.000 129.26000 ?  31   GLU R    OE1 1 
ATOM   4499 O OE2 . GLU C 3 52  ? 28.42400 41.19300 83.04500  1.000 121.23000 ?  31   GLU R    OE2 1 
ATOM   4500 N N   . TYR C 3 53  ? 30.19200 45.50100 80.63800  1.000 107.56000 ?  32   TYR R    N   1 
ATOM   4501 C CA  . TYR C 3 53  ? 29.88800 45.24000 79.22600  1.000 100.63000 ?  32   TYR R    CA  1 
ATOM   4502 C C   . TYR C 3 53  ? 30.12200 43.77200 78.87600  1.000 99.88000  ?  32   TYR R    C   1 
ATOM   4503 O O   . TYR C 3 53  ? 31.24200 43.26500 79.01800  1.000 97.75000  ?  32   TYR R    O   1 
ATOM   4504 C CB  . TYR C 3 53  ? 30.74000 46.12900 78.31900  1.000 90.81000  ?  32   TYR R    CB  1 
ATOM   4505 C CG  . TYR C 3 53  ? 30.45700 45.97900 76.83100  1.000 90.14000  ?  32   TYR R    CG  1 
ATOM   4506 C CD1 . TYR C 3 53  ? 31.13400 45.04300 76.05900  1.000 89.45000  ?  32   TYR R    CD1 1 
ATOM   4507 C CD2 . TYR C 3 53  ? 29.51700 46.77700 76.19700  1.000 94.49000  ?  32   TYR R    CD2 1 
ATOM   4508 C CE1 . TYR C 3 53  ? 30.88100 44.91100 74.69600  1.000 85.24000  ?  32   TYR R    CE1 1 
ATOM   4509 C CE2 . TYR C 3 53  ? 29.25600 46.65200 74.84200  1.000 86.31000  ?  32   TYR R    CE2 1 
ATOM   4510 C CZ  . TYR C 3 53  ? 29.93800 45.71900 74.10000  1.000 91.20000  ?  32   TYR R    CZ  1 
ATOM   4511 O OH  . TYR C 3 53  ? 29.65900 45.60500 72.75300  1.000 103.67000 ?  32   TYR R    OH  1 
ATOM   4512 N N   . ASP C 3 54  ? 29.08100 43.10100 78.38100  1.000 97.87000  ?  33   ASP R    N   1 
ATOM   4513 C CA  . ASP C 3 54  ? 29.21400 41.73200 77.88700  1.000 96.73000  ?  33   ASP R    CA  1 
ATOM   4514 C C   . ASP C 3 54  ? 28.86200 41.65600 76.41000  1.000 98.85000  ?  33   ASP R    C   1 
ATOM   4515 O O   . ASP C 3 54  ? 27.70700 41.92500 76.04000  1.000 101.77000 ?  33   ASP R    O   1 
ATOM   4516 C CB  . ASP C 3 54  ? 28.35000 40.76500 78.68900  1.000 103.47000 ?  33   ASP R    CB  1 
ATOM   4517 C CG  . ASP C 3 54  ? 28.70200 39.31600 78.41800  1.000 101.75000 ?  33   ASP R    CG  1 
ATOM   4518 O OD1 . ASP C 3 54  ? 28.58300 38.87300 77.26600  1.000 96.60000  ?  33   ASP R    OD1 1 
ATOM   4519 O OD2 . ASP C 3 54  ? 29.18800 38.63800 79.34200  1.000 112.81000 ?  33   ASP R    OD2 1 
ATOM   4520 N N   . PRO C 3 55  ? 29.81000 41.27400 75.53600  1.000 95.98000  ?  34   PRO R    N   1 
ATOM   4521 C CA  . PRO C 3 55  ? 29.56400 41.32800 74.09400  1.000 90.59000  ?  34   PRO R    CA  1 
ATOM   4522 C C   . PRO C 3 55  ? 28.97000 40.05500 73.50300  1.000 97.39000  ?  34   PRO R    C   1 
ATOM   4523 O O   . PRO C 3 55  ? 28.97100 39.87300 72.27900  1.000 104.29000 ?  34   PRO R    O   1 
ATOM   4524 C CB  . PRO C 3 55  ? 30.96300 41.59800 73.54100  1.000 88.70000  ?  34   PRO R    CB  1 
ATOM   4525 C CG  . PRO C 3 55  ? 31.86100 40.89200 74.47500  1.000 78.65000  ?  34   PRO R    CG  1 
ATOM   4526 C CD  . PRO C 3 55  ? 31.21800 40.95900 75.83200  1.000 93.45000  ?  34   PRO R    CD  1 
ATOM   4527 N N   . THR C 3 56  ? 28.46800 39.16300 74.35600  1.000 99.03000  ?  35   THR R    N   1 
ATOM   4528 C CA  . THR C 3 56  ? 27.72700 38.00200 73.87300  1.000 99.97000  ?  35   THR R    CA  1 
ATOM   4529 C C   . THR C 3 56  ? 26.26700 38.33900 73.61800  1.000 102.60000 ?  35   THR R    C   1 
ATOM   4530 O O   . THR C 3 56  ? 25.67700 37.87000 72.63900  1.000 107.85000 ?  35   THR R    O   1 
ATOM   4531 C CB  . THR C 3 56  ? 27.83400 36.85800 74.87800  1.000 99.70000  ?  35   THR R    CB  1 
ATOM   4532 O OG1 . THR C 3 56  ? 29.19400 36.74100 75.31600  1.000 99.64000  ?  35   THR R    OG1 1 
ATOM   4533 C CG2 . THR C 3 56  ? 27.34600 35.53900 74.27100  1.000 104.38000 ?  35   THR R    CG2 1 
ATOM   4534 N N   . ILE C 3 57  ? 25.69000 39.17600 74.47500  1.000 103.68000 ?  36   ILE R    N   1 
ATOM   4535 C CA  . ILE C 3 57  ? 24.27100 39.46100 74.39900  1.000 106.47000 ?  36   ILE R    CA  1 
ATOM   4536 C C   . ILE C 3 57  ? 23.94900 40.19600 73.09800  1.000 106.83000 ?  36   ILE R    C   1 
ATOM   4537 O O   . ILE C 3 57  ? 24.80200 40.87300 72.50800  1.000 98.71000  ?  36   ILE R    O   1 
ATOM   4538 C CB  . ILE C 3 57  ? 23.86400 40.29300 75.62300  1.000 104.98000 ?  36   ILE R    CB  1 
ATOM   4539 C CG1 . ILE C 3 57  ? 24.55700 39.72500 76.87200  1.000 101.64000 ?  36   ILE R    CG1 1 
ATOM   4540 C CG2 . ILE C 3 57  ? 22.35300 40.25400 75.77500  1.000 113.18000 ?  36   ILE R    CG2 1 
ATOM   4541 C CD1 . ILE C 3 57  ? 24.54900 40.65700 78.07800  1.000 105.95000 ?  36   ILE R    CD1 1 
ATOM   4542 N N   . GLU C 3 58  ? 22.69900 40.05400 72.64400  1.000 110.38000 ?  37   GLU R    N   1 
ATOM   4543 C CA  . GLU C 3 58  ? 22.27000 40.75300 71.43600  1.000 105.46000 ?  37   GLU R    CA  1 
ATOM   4544 C C   . GLU C 3 58  ? 22.24000 42.26000 71.65300  1.000 101.08000 ?  37   GLU R    C   1 
ATOM   4545 O O   . GLU C 3 58  ? 22.62500 43.03000 70.76400  1.000 96.39000  ?  37   GLU R    O   1 
ATOM   4546 C CB  . GLU C 3 58  ? 20.89400 40.25700 71.00600  1.000 106.99000 ?  37   GLU R    CB  1 
ATOM   4547 C CG  . GLU C 3 58  ? 20.20000 41.17100 70.01400  1.000 107.56000 ?  37   GLU R    CG  1 
ATOM   4548 C CD  . GLU C 3 58  ? 18.69800 40.92900 69.93400  1.000 120.23000 ?  37   GLU R    CD  1 
ATOM   4549 O OE1 . GLU C 3 58  ? 18.14200 40.18500 70.78300  1.000 121.48000 ?  37   GLU R    OE1 1 
ATOM   4550 O OE2 . GLU C 3 58  ? 18.06800 41.49400 69.01400  1.000 122.82000 ?  37   GLU R    OE2 1 
ATOM   4551 N N   . ASP C 3 59  ? 21.79600 42.70100 72.83400  1.000 105.33000 ?  38   ASP R    N   1 
ATOM   4552 C CA  . ASP C 3 59  ? 21.73100 44.13200 73.13000  1.000 110.03000 ?  38   ASP R    CA  1 
ATOM   4553 C C   . ASP C 3 59  ? 23.07900 44.83400 73.03300  1.000 108.17000 ?  38   ASP R    C   1 
ATOM   4554 O O   . ASP C 3 59  ? 23.11800 46.07000 73.10900  1.000 104.56000 ?  38   ASP R    O   1 
ATOM   4555 C CB  . ASP C 3 59  ? 21.16100 44.38600 74.53000  1.000 109.38000 ?  38   ASP R    CB  1 
ATOM   4556 C CG  . ASP C 3 59  ? 20.44600 45.73200 74.63000  1.000 113.31000 ?  38   ASP R    CG  1 
ATOM   4557 O OD1 . ASP C 3 59  ? 19.25700 45.82700 74.24600  1.000 112.26000 ?  38   ASP R    OD1 1 
ATOM   4558 O OD2 . ASP C 3 59  ? 21.09900 46.71100 75.06000  1.000 116.14000 ?  38   ASP R    OD2 1 
ATOM   4559 N N   . SER C 3 60  ? 24.17500 44.09000 72.87400  1.000 106.46000 ?  39   SER R    N   1 
ATOM   4560 C CA  . SER C 3 60  ? 25.50100 44.68900 72.87100  1.000 99.54000  ?  39   SER R    CA  1 
ATOM   4561 C C   . SER C 3 60  ? 25.84800 45.34900 71.55100  1.000 96.10000  ?  39   SER R    C   1 
ATOM   4562 O O   . SER C 3 60  ? 26.87200 46.03600 71.48800  1.000 96.21000  ?  39   SER R    O   1 
ATOM   4563 C CB  . SER C 3 60  ? 26.55900 43.63500 73.20800  1.000 99.93000  ?  39   SER R    CB  1 
ATOM   4564 O OG  . SER C 3 60  ? 26.75800 42.74500 72.12200  1.000 102.84000 ?  39   SER R    OG  1 
ATOM   4565 N N   . TYR C 3 61  ? 25.03500 45.14300 70.49900  1.000 93.31000  ?  40   TYR R    N   1 
ATOM   4566 C CA  . TYR C 3 61  ? 25.30500 45.77000 69.21200  1.000 88.57000  ?  40   TYR R    CA  1 
ATOM   4567 C C   . TYR C 3 61  ? 24.07200 46.33400 68.51200  1.000 91.55000  ?  40   TYR R    C   1 
ATOM   4568 O O   . TYR C 3 61  ? 24.18400 46.73800 67.34500  1.000 88.34000  ?  40   TYR R    O   1 
ATOM   4569 C CB  . TYR C 3 61  ? 26.00800 44.79400 68.28100  1.000 82.55000  ?  40   TYR R    CB  1 
ATOM   4570 C CG  . TYR C 3 61  ? 25.28200 43.50500 68.07100  1.000 80.61000  ?  40   TYR R    CG  1 
ATOM   4571 C CD1 . TYR C 3 61  ? 24.07100 43.47100 67.41100  1.000 83.24000  ?  40   TYR R    CD1 1 
ATOM   4572 C CD2 . TYR C 3 61  ? 25.83800 42.31100 68.48800  1.000 80.96000  ?  40   TYR R    CD2 1 
ATOM   4573 C CE1 . TYR C 3 61  ? 23.41200 42.29200 67.21000  1.000 86.65000  ?  40   TYR R    CE1 1 
ATOM   4574 C CE2 . TYR C 3 61  ? 25.19900 41.12100 68.28300  1.000 78.56000  ?  40   TYR R    CE2 1 
ATOM   4575 C CZ  . TYR C 3 61  ? 23.98300 41.11700 67.64800  1.000 84.15000  ?  40   TYR R    CZ  1 
ATOM   4576 O OH  . TYR C 3 61  ? 23.32300 39.93700 67.43600  1.000 88.73000  ?  40   TYR R    OH  1 
ATOM   4577 N N   . ARG C 3 62  ? 22.90100 46.34900 69.15300  1.000 92.27000  ?  41   ARG R    N   1 
ATOM   4578 C CA  . ARG C 3 62  ? 21.74800 47.09200 68.66100  1.000 88.90000  ?  41   ARG R    CA  1 
ATOM   4579 C C   . ARG C 3 62  ? 21.42400 48.19900 69.63900  1.000 92.14000  ?  41   ARG R    C   1 
ATOM   4580 O O   . ARG C 3 62  ? 21.55300 48.02100 70.85500  1.000 98.68000  ?  41   ARG R    O   1 
ATOM   4581 C CB  . ARG C 3 62  ? 20.50000 46.24900 68.52200  1.000 94.28000  ?  41   ARG R    CB  1 
ATOM   4582 C CG  . ARG C 3 62  ? 20.58600 45.09600 67.60700  1.000 96.91000  ?  41   ARG R    CG  1 
ATOM   4583 C CD  . ARG C 3 62  ? 19.27700 44.35500 67.65300  1.000 98.81000  ?  41   ARG R    CD  1 
ATOM   4584 N NE  . ARG C 3 62  ? 19.30500 43.27000 66.69000  1.000 106.61000 ?  41   ARG R    NE  1 
ATOM   4585 C CZ  . ARG C 3 62  ? 18.95100 43.40700 65.42200  1.000 109.09000 ?  41   ARG R    CZ  1 
ATOM   4586 N NH1 . ARG C 3 62  ? 18.51200 44.56600 64.95100  1.000 104.03000 ?  41   ARG R    NH1 1 
ATOM   4587 N NH2 . ARG C 3 62  ? 19.05800 42.36200 64.60300  1.000 110.27000 ?  41   ARG R    NH2 1 
ATOM   4588 N N   . LYS C 3 63  ? 20.96300 49.32300 69.11400  1.000 84.46000  ?  42   LYS R    N   1 
ATOM   4589 C CA  . LYS C 3 63  ? 20.57400 50.41500 69.98600  1.000 89.47000  ?  42   LYS R    CA  1 
ATOM   4590 C C   . LYS C 3 63  ? 19.46500 51.14500 69.27300  1.000 90.81000  ?  42   LYS R    C   1 
ATOM   4591 O O   . LYS C 3 63  ? 19.60200 51.48000 68.09400  1.000 86.50000  ?  42   LYS R    O   1 
ATOM   4592 C CB  . LYS C 3 63  ? 21.74900 51.36300 70.30300  1.000 90.34000  ?  42   LYS R    CB  1 
ATOM   4593 C CG  . LYS C 3 63  ? 21.45700 52.53800 71.26800  1.000 87.79000  ?  42   LYS R    CG  1 
ATOM   4594 C CD  . LYS C 3 63  ? 22.68300 53.45300 71.37600  1.000 90.94000  ?  42   LYS R    CD  1 
ATOM   4595 C CE  . LYS C 3 63  ? 22.43900 54.77400 72.14800  1.000 99.98000  ?  42   LYS R    CE  1 
ATOM   4596 N NZ  . LYS C 3 63  ? 23.50900 55.86500 71.93100  1.000 91.25000  ?  42   LYS R    NZ  1 
ATOM   4597 N N   . GLN C 3 64  ? 18.35900 51.33100 69.97500  1.000 95.31000  ?  43   GLN R    N   1 
ATOM   4598 C CA  . GLN C 3 64  ? 17.32900 52.24800 69.52900  1.000 91.53000  ?  43   GLN R    CA  1 
ATOM   4599 C C   . GLN C 3 64  ? 17.81500 53.66200 69.78100  1.000 88.77000  ?  43   GLN R    C   1 
ATOM   4600 O O   . GLN C 3 64  ? 18.25500 53.97900 70.89000  1.000 89.31000  ?  43   GLN R    O   1 
ATOM   4601 C CB  . GLN C 3 64  ? 16.03400 51.96300 70.26900  1.000 89.98000  ?  43   GLN R    CB  1 
ATOM   4602 C CG  . GLN C 3 64  ? 14.82300 52.56400 69.61700  1.000 101.79000 ?  43   GLN R    CG  1 
ATOM   4603 C CD  . GLN C 3 64  ? 13.65800 51.60300 69.58200  1.000 106.04000 ?  43   GLN R    CD  1 
ATOM   4604 O OE1 . GLN C 3 64  ? 13.42100 50.85600 70.54100  1.000 105.39000 ?  43   GLN R    OE1 1 
ATOM   4605 N NE2 . GLN C 3 64  ? 12.89800 51.64100 68.49200  1.000 100.44000 ?  43   GLN R    NE2 1 
ATOM   4606 N N   . VAL C 3 65  ? 17.80000 54.49700 68.74800  1.000 86.62000  ?  44   VAL R    N   1 
ATOM   4607 C CA  . VAL C 3 65  ? 18.17400 55.89400 68.90300  1.000 94.25000  ?  44   VAL R    CA  1 
ATOM   4608 C C   . VAL C 3 65  ? 17.14700 56.71500 68.13900  1.000 96.76000  ?  44   VAL R    C   1 
ATOM   4609 O O   . VAL C 3 65  ? 16.37800 56.18300 67.33500  1.000 93.43000  ?  44   VAL R    O   1 
ATOM   4610 C CB  . VAL C 3 65  ? 19.61000 56.20800 68.40300  1.000 88.65000  ?  44   VAL R    CB  1 
ATOM   4611 C CG1 . VAL C 3 65  ? 20.64000 55.27500 69.04700  1.000 83.84000  ?  44   VAL R    CG1 1 
ATOM   4612 C CG2 . VAL C 3 65  ? 19.67700 56.15400 66.89400  1.000 86.74000  ?  44   VAL R    CG2 1 
ATOM   4613 N N   . VAL C 3 66  ? 17.12700 58.02200 68.41300  1.000 97.96000  ?  45   VAL R    N   1 
ATOM   4614 C CA  . VAL C 3 66  ? 16.28600 58.96700 67.67500  1.000 100.17000 ?  45   VAL R    CA  1 
ATOM   4615 C C   . VAL C 3 66  ? 17.18300 60.01200 67.02800  1.000 98.46000  ?  45   VAL R    C   1 
ATOM   4616 O O   . VAL C 3 66  ? 17.80000 60.83600 67.71900  1.000 94.63000  ?  45   VAL R    O   1 
ATOM   4617 C CB  . VAL C 3 66  ? 15.22300 59.62500 68.56000  1.000 101.79000 ?  45   VAL R    CB  1 
ATOM   4618 C CG1 . VAL C 3 66  ? 14.45600 60.63600 67.74700  1.000 94.77000  ?  45   VAL R    CG1 1 
ATOM   4619 C CG2 . VAL C 3 66  ? 14.25900 58.57000 69.09800  1.000 100.73000 ?  45   VAL R    CG2 1 
ATOM   4620 N N   . ILE C 3 67  ? 17.25100 59.98200 65.70100  1.000 96.04000  ?  46   ILE R    N   1 
ATOM   4621 C CA  . ILE C 3 67  ? 18.08100 60.89400 64.93400  1.000 95.18000  ?  46   ILE R    CA  1 
ATOM   4622 C C   . ILE C 3 67  ? 17.15500 61.76500 64.11800  1.000 97.63000  ?  46   ILE R    C   1 
ATOM   4623 O O   . ILE C 3 67  ? 16.37500 61.25000 63.31000  1.000 101.81000 ?  46   ILE R    O   1 
ATOM   4624 C CB  . ILE C 3 67  ? 19.06300 60.15400 64.01900  1.000 93.82000  ?  46   ILE R    CB  1 
ATOM   4625 C CG1 . ILE C 3 67  ? 19.94600 59.20900 64.83200  1.000 90.86000  ?  46   ILE R    CG1 1 
ATOM   4626 C CG2 . ILE C 3 67  ? 19.91300 61.16300 63.26700  1.000 91.42000  ?  46   ILE R    CG2 1 
ATOM   4627 C CD1 . ILE C 3 67  ? 20.85700 58.36200 63.99600  1.000 86.00000  ?  46   ILE R    CD1 1 
ATOM   4628 N N   . ASP C 3 68  ? 17.24400 63.08100 64.32600  1.000 99.16000  ?  47   ASP R    N   1 
ATOM   4629 C CA  . ASP C 3 68  ? 16.44100 64.06900 63.59500  1.000 100.87000 ?  47   ASP R    CA  1 
ATOM   4630 C C   . ASP C 3 68  ? 14.94700 63.80100 63.74500  1.000 103.82000 ?  47   ASP R    C   1 
ATOM   4631 O O   . ASP C 3 68  ? 14.18700 63.80900 62.77000  1.000 99.13000  ?  47   ASP R    O   1 
ATOM   4632 C CB  . ASP C 3 68  ? 16.83300 64.12100 62.12200  1.000 99.36000  ?  47   ASP R    CB  1 
ATOM   4633 C CG  . ASP C 3 68  ? 18.24800 64.57600 61.93700  1.000 105.58000 ?  47   ASP R    CG  1 
ATOM   4634 O OD1 . ASP C 3 68  ? 18.89300 64.84700 62.98100  1.000 103.86000 ?  47   ASP R    OD1 1 
ATOM   4635 O OD2 . ASP C 3 68  ? 18.70500 64.67600 60.77000  1.000 105.56000 ?  47   ASP R    OD2 1 
ATOM   4636 N N   . GLY C 3 69  ? 14.52800 63.57100 64.98900  1.000 101.89000 ?  48   GLY R    N   1 
ATOM   4637 C CA  . GLY C 3 69  ? 13.14200 63.27800 65.27000  1.000 98.19000  ?  48   GLY R    CA  1 
ATOM   4638 C C   . GLY C 3 69  ? 12.77200 61.84800 64.94200  1.000 102.45000 ?  48   GLY R    C   1 
ATOM   4639 O O   . GLY C 3 69  ? 12.05100 61.20500 65.71300  1.000 107.07000 ?  48   GLY R    O   1 
ATOM   4640 N N   . GLU C 3 70  ? 13.25900 61.32800 63.81400  1.000 101.21000 ?  49   GLU R    N   1 
ATOM   4641 C CA  . GLU C 3 70  ? 12.89500 59.97700 63.40500  1.000 103.89000 ?  49   GLU R    CA  1 
ATOM   4642 C C   . GLU C 3 70  ? 13.60600 58.92600 64.25500  1.000 104.40000 ?  49   GLU R    C   1 
ATOM   4643 O O   . GLU C 3 70  ? 14.83500 58.93400 64.38400  1.000 104.42000 ?  49   GLU R    O   1 
ATOM   4644 C CB  . GLU C 3 70  ? 13.21000 59.76000 61.93000  1.000 103.44000 ?  49   GLU R    CB  1 
ATOM   4645 C CG  . GLU C 3 70  ? 12.93700 58.32300 61.50800  1.000 114.68000 ?  49   GLU R    CG  1 
ATOM   4646 C CD  . GLU C 3 70  ? 13.11800 58.09100 60.02000  1.000 117.36000 ?  49   GLU R    CD  1 
ATOM   4647 O OE1 . GLU C 3 70  ? 13.07500 59.08700 59.25600  1.000 114.36000 ?  49   GLU R    OE1 1 
ATOM   4648 O OE2 . GLU C 3 70  ? 13.32700 56.91100 59.63200  1.000 113.47000 ?  49   GLU R    OE2 1 
ATOM   4649 N N   . THR C 3 71  ? 12.82600 58.01800 64.83100  1.000 100.98000 ?  50   THR R    N   1 
ATOM   4650 C CA  . THR C 3 71  ? 13.36100 56.93100 65.63400  1.000 102.87000 ?  50   THR R    CA  1 
ATOM   4651 C C   . THR C 3 71  ? 13.75500 55.76000 64.73300  1.000 106.94000 ?  50   THR R    C   1 
ATOM   4652 O O   . THR C 3 71  ? 13.01500 55.38000 63.81600  1.000 107.19000 ?  50   THR R    O   1 
ATOM   4653 C CB  . THR C 3 71  ? 12.33800 56.50300 66.70000  1.000 106.66000 ?  50   THR R    CB  1 
ATOM   4654 O OG1 . THR C 3 71  ? 12.75400 55.29200 67.36000  1.000 101.64000 ?  50   THR R    OG1 1 
ATOM   4655 C CG2 . THR C 3 71  ? 10.94800 56.32800 66.08100  1.000 113.51000 ?  50   THR R    CG2 1 
ATOM   4656 N N   . CYS C 3 72  ? 14.94600 55.20900 64.99200  1.000 104.95000 ?  51   CYS R    N   1 
ATOM   4657 C CA  . CYS C 3 72  ? 15.49700 54.10000 64.22400  1.000 96.66000  ?  51   CYS R    CA  1 
ATOM   4658 C C   . CYS C 3 72  ? 16.30100 53.19600 65.14900  1.000 95.63000  ?  51   CYS R    C   1 
ATOM   4659 O O   . CYS C 3 72  ? 16.49700 53.48600 66.33700  1.000 92.88000  ?  51   CYS R    O   1 
ATOM   4660 C CB  . CYS C 3 72  ? 16.36600 54.61000 63.08500  1.000 95.42000  ?  51   CYS R    CB  1 
ATOM   4661 S SG  . CYS C 3 72  ? 17.60300 55.76100 63.68700  1.000 98.84000  ?  51   CYS R    SG  1 
ATOM   4662 N N   . LEU C 3 73  ? 16.77200 52.08800 64.58300  1.000 97.03000  ?  52   LEU R    N   1 
ATOM   4663 C CA  . LEU C 3 73  ? 17.48500 51.06600 65.33600  1.000 92.18000  ?  52   LEU R    CA  1 
ATOM   4664 C C   . LEU C 3 73  ? 18.80000 50.76500 64.63400  1.000 87.57000  ?  52   LEU R    C   1 
ATOM   4665 O O   . LEU C 3 73  ? 18.80800 50.25400 63.51200  1.000 87.90000  ?  52   LEU R    O   1 
ATOM   4666 C CB  . LEU C 3 73  ? 16.64600 49.80000 65.47200  1.000 89.15000  ?  52   LEU R    CB  1 
ATOM   4667 C CG  . LEU C 3 73  ? 17.50300 48.59400 65.81200  1.000 92.61000  ?  52   LEU R    CG  1 
ATOM   4668 C CD1 . LEU C 3 73  ? 18.12000 48.77000 67.19200  1.000 93.85000  ?  52   LEU R    CD1 1 
ATOM   4669 C CD2 . LEU C 3 73  ? 16.68700 47.32500 65.72800  1.000 102.04000 ?  52   LEU R    CD2 1 
ATOM   4670 N N   . LEU C 3 74  ? 19.90000 51.06400 65.30900  1.000 85.46000  ?  53   LEU R    N   1 
ATOM   4671 C CA  . LEU C 3 74  ? 21.23300 50.91800 64.75600  1.000 79.70000  ?  53   LEU R    CA  1 
ATOM   4672 C C   . LEU C 3 74  ? 21.74300 49.50600 65.02300  1.000 82.32000  ?  53   LEU R    C   1 
ATOM   4673 O O   . LEU C 3 74  ? 21.86600 49.10300 66.18400  1.000 83.48000  ?  53   LEU R    O   1 
ATOM   4674 C CB  . LEU C 3 74  ? 22.15800 51.96100 65.37400  1.000 72.79000  ?  53   LEU R    CB  1 
ATOM   4675 C CG  . LEU C 3 74  ? 22.22200 53.30500 64.65100  1.000 77.44000  ?  53   LEU R    CG  1 
ATOM   4676 C CD1 . LEU C 3 74  ? 20.88200 53.72200 64.11900  1.000 85.09000  ?  53   LEU R    CD1 1 
ATOM   4677 C CD2 . LEU C 3 74  ? 22.80300 54.38400 65.52300  1.000 66.15000  ?  53   LEU R    CD2 1 
ATOM   4678 N N   . ASP C 3 75  ? 22.03100 48.75300 63.94900  1.000 83.37000  ?  54   ASP R    N   1 
ATOM   4679 C CA  . ASP C 3 75  ? 22.64600 47.42300 64.03400  1.000 83.41000  ?  54   ASP R    CA  1 
ATOM   4680 C C   . ASP C 3 75  ? 24.11400 47.54400 63.63700  1.000 79.50000  ?  54   ASP R    C   1 
ATOM   4681 O O   . ASP C 3 75  ? 24.42900 47.73000 62.45800  1.000 78.13000  ?  54   ASP R    O   1 
ATOM   4682 C CB  . ASP C 3 75  ? 21.94500 46.42000 63.12100  1.000 87.42000  ?  54   ASP R    CB  1 
ATOM   4683 C CG  . ASP C 3 75  ? 22.45500 44.99200 63.31100  1.000 91.58000  ?  54   ASP R    CG  1 
ATOM   4684 O OD1 . ASP C 3 75  ? 23.52600 44.78700 63.92400  1.000 89.95000  ?  54   ASP R    OD1 1 
ATOM   4685 O OD2 . ASP C 3 75  ? 21.77500 44.05800 62.83500  1.000 99.66000  ?  54   ASP R    OD2 1 
ATOM   4686 N N   . ILE C 3 76  ? 25.01500 47.37700 64.60000  1.000 76.38000  ?  55   ILE R    N   1 
ATOM   4687 C CA  . ILE C 3 76  ? 26.40000 47.77100 64.41900  1.000 70.40000  ?  55   ILE R    CA  1 
ATOM   4688 C C   . ILE C 3 76  ? 27.30900 46.55100 64.40300  1.000 72.12000  ?  55   ILE R    C   1 
ATOM   4689 O O   . ILE C 3 76  ? 27.37500 45.79300 65.37700  1.000 69.61000  ?  55   ILE R    O   1 
ATOM   4690 C CB  . ILE C 3 76  ? 26.80600 48.78000 65.48100  1.000 66.19000  ?  55   ILE R    CB  1 
ATOM   4691 C CG1 . ILE C 3 76  ? 25.75800 49.87700 65.42600  1.000 66.48000  ?  55   ILE R    CG1 1 
ATOM   4692 C CG2 . ILE C 3 76  ? 28.18400 49.28800 65.18900  1.000 69.56000  ?  55   ILE R    CG2 1 
ATOM   4693 C CD1 . ILE C 3 76  ? 26.21000 51.17900 65.88600  1.000 69.56000  ?  55   ILE R    CD1 1 
ATOM   4694 N N   . LEU C 3 77  ? 28.01400 46.37300 63.27400  1.000 76.41000  ?  56   LEU R    N   1 
ATOM   4695 C CA  . LEU C 3 77  ? 28.95800 45.27600 63.06100  1.000 73.74000  ?  56   LEU R    CA  1 
ATOM   4696 C C   . LEU C 3 77  ? 30.37200 45.80800 63.22300  1.000 72.83000  ?  56   LEU R    C   1 
ATOM   4697 O O   . LEU C 3 77  ? 30.83700 46.62100 62.41600  1.000 68.91000  ?  56   LEU R    O   1 
ATOM   4698 C CB  . LEU C 3 77  ? 28.79700 44.65100 61.68100  1.000 74.67000  ?  56   LEU R    CB  1 
ATOM   4699 C CG  . LEU C 3 77  ? 29.96700 43.74300 61.30200  1.000 71.21000  ?  56   LEU R    CG  1 
ATOM   4700 C CD1 . LEU C 3 77  ? 29.90900 42.53500 62.19200  1.000 65.23000  ?  56   LEU R    CD1 1 
ATOM   4701 C CD2 . LEU C 3 77  ? 29.90400 43.34800 59.81600  1.000 68.43000  ?  56   LEU R    CD2 1 
ATOM   4702 N N   . ASP C 3 78  ? 31.04200 45.34400 64.27000  1.000 73.97000  ?  57   ASP R    N   1 
ATOM   4703 C CA  . ASP C 3 78  ? 32.41900 45.68600 64.57200  1.000 70.46000  ?  57   ASP R    CA  1 
ATOM   4704 C C   . ASP C 3 78  ? 33.14500 44.36900 64.78400  1.000 70.63000  ?  57   ASP R    C   1 
ATOM   4705 O O   . ASP C 3 78  ? 32.66400 43.52100 65.53900  1.000 72.32000  ?  57   ASP R    O   1 
ATOM   4706 C CB  . ASP C 3 78  ? 32.46900 46.57700 65.81100  1.000 76.25000  ?  57   ASP R    CB  1 
ATOM   4707 C CG  . ASP C 3 78  ? 33.81800 46.56800 66.50400  1.000 82.44000  ?  57   ASP R    CG  1 
ATOM   4708 O OD1 . ASP C 3 78  ? 34.85900 46.65300 65.79900  1.000 81.58000  ?  57   ASP R    OD1 1 
ATOM   4709 O OD2 . ASP C 3 78  ? 33.82400 46.49100 67.76400  1.000 80.33000  ?  57   ASP R    OD2 1 
ATOM   4710 N N   . THR C 3 79  ? 34.26500 44.17200 64.08400  1.000 69.98000  ?  58   THR R    N   1 
ATOM   4711 C CA  . THR C 3 79  ? 34.92700 42.86900 64.04300  1.000 70.86000  ?  58   THR R    CA  1 
ATOM   4712 C C   . THR C 3 79  ? 36.32800 42.90100 64.63900  1.000 68.47000  ?  58   THR R    C   1 
ATOM   4713 O O   . THR C 3 79  ? 37.11200 41.96900 64.40900  1.000 67.40000  ?  58   THR R    O   1 
ATOM   4714 C CB  . THR C 3 79  ? 35.01400 42.33000 62.60900  1.000 73.26000  ?  58   THR R    CB  1 
ATOM   4715 O OG1 . THR C 3 79  ? 35.91300 43.15300 61.84400  1.000 80.98000  ?  58   THR R    OG1 1 
ATOM   4716 C CG2 . THR C 3 79  ? 33.64300 42.25300 61.94700  1.000 66.66000  ?  58   THR R    CG2 1 
ATOM   4717 N N   . ALA C 3 80  ? 36.65300 43.95500 65.38600  1.000 67.21000  ?  59   ALA R    N   1 
ATOM   4718 C CA  . ALA C 3 80  ? 38.01100 44.17800 65.85500  1.000 63.49000  ?  59   ALA R    CA  1 
ATOM   4719 C C   . ALA C 3 80  ? 38.58500 42.89000 66.41600  1.000 61.46000  ?  59   ALA R    C   1 
ATOM   4720 O O   . ALA C 3 80  ? 37.89900 42.13300 67.10300  1.000 64.95000  ?  59   ALA R    O   1 
ATOM   4721 C CB  . ALA C 3 80  ? 38.01900 45.29000 66.90700  1.000 65.43000  ?  59   ALA R    CB  1 
ATOM   4722 N N   . GLY C 3 81  ? 39.82100 42.60000 66.06000  1.000 59.57000  ?  60   GLY R    N   1 
ATOM   4723 C CA  . GLY C 3 81  ? 40.43500 41.36500 66.45400  1.000 62.43000  ?  60   GLY R    CA  1 
ATOM   4724 C C   . GLY C 3 81  ? 40.49600 40.32300 65.35600  1.000 65.51000  ?  60   GLY R    C   1 
ATOM   4725 O O   . GLY C 3 81  ? 41.34200 39.42000 65.41600  1.000 69.27000  ?  60   GLY R    O   1 
ATOM   4726 N N   . GLN C 3 82  ? 39.61100 40.41200 64.36600  1.000 60.88000  ?  61   GLN R    N   1 
ATOM   4727 C CA  . GLN C 3 82  ? 39.64900 39.52300 63.22100  1.000 58.93000  ?  61   GLN R    CA  1 
ATOM   4728 C C   . GLN C 3 82  ? 40.34500 40.15300 62.03800  1.000 64.04000  ?  61   GLN R    C   1 
ATOM   4729 O O   . GLN C 3 82  ? 40.13500 39.71100 60.89700  1.000 65.89000  ?  61   GLN R    O   1 
ATOM   4730 C CB  . GLN C 3 82  ? 38.24100 39.11000 62.82600  1.000 63.19000  ?  61   GLN R    CB  1 
ATOM   4731 C CG  . GLN C 3 82  ? 37.34500 38.79100 63.97800  1.000 67.45000  ?  61   GLN R    CG  1 
ATOM   4732 C CD  . GLN C 3 82  ? 36.02300 38.24900 63.51200  1.000 66.90000  ?  61   GLN R    CD  1 
ATOM   4733 O OE1 . GLN C 3 82  ? 35.95500 37.22300 62.84000  1.000 63.56000  ?  61   GLN R    OE1 1 
ATOM   4734 N NE2 . GLN C 3 82  ? 34.95400 38.93900 63.87100  1.000 71.34000  ?  61   GLN R    NE2 1 
ATOM   4735 N N   . GLU C 3 83  ? 41.15900 41.18500 62.28300  1.000 66.33000  ?  62   GLU R    N   1 
ATOM   4736 C CA  . GLU C 3 83  ? 41.80400 41.90200 61.18600  1.000 65.96000  ?  62   GLU R    CA  1 
ATOM   4737 C C   . GLU C 3 83  ? 42.72200 40.98500 60.39600  1.000 66.69000  ?  62   GLU R    C   1 
ATOM   4738 O O   . GLU C 3 83  ? 42.79300 41.09300 59.16600  1.000 68.57000  ?  62   GLU R    O   1 
ATOM   4739 C CB  . GLU C 3 83  ? 42.57500 43.10900 61.71500  1.000 60.19000  ?  62   GLU R    CB  1 
ATOM   4740 C CG  . GLU C 3 83  ? 41.69500 44.25700 62.13700  1.000 65.45000  ?  62   GLU R    CG  1 
ATOM   4741 C CD  . GLU C 3 83  ? 41.54200 44.31900 63.64400  1.000 71.81000  ?  62   GLU R    CD  1 
ATOM   4742 O OE1 . GLU C 3 83  ? 41.94200 43.32600 64.30200  1.000 68.76000  ?  62   GLU R    OE1 1 
ATOM   4743 O OE2 . GLU C 3 83  ? 41.02400 45.34400 64.17000  1.000 74.65000  ?  62   GLU R    OE2 1 
ATOM   4744 N N   . GLU C 3 84  ? 43.41200 40.05700 61.07700  1.000 64.05000  ?  63   GLU R    N   1 
ATOM   4745 C CA  . GLU C 3 84  ? 44.32300 39.14300 60.39000  1.000 66.90000  ?  63   GLU R    CA  1 
ATOM   4746 C C   . GLU C 3 84  ? 43.59400 38.19500 59.44100  1.000 64.40000  ?  63   GLU R    C   1 
ATOM   4747 O O   . GLU C 3 84  ? 44.23100 37.59200 58.57300  1.000 64.08000  ?  63   GLU R    O   1 
ATOM   4748 C CB  . GLU C 3 84  ? 45.12800 38.34100 61.41400  1.000 71.07000  ?  63   GLU R    CB  1 
ATOM   4749 C CG  . GLU C 3 84  ? 45.89600 39.19200 62.41000  1.000 79.69000  ?  63   GLU R    CG  1 
ATOM   4750 C CD  . GLU C 3 84  ? 47.22200 39.74700 61.85700  1.000 83.55000  ?  63   GLU R    CD  1 
ATOM   4751 O OE1 . GLU C 3 84  ? 47.80200 39.12600 60.93000  1.000 83.02000  ?  63   GLU R    OE1 1 
ATOM   4752 O OE2 . GLU C 3 84  ? 47.66800 40.82000 62.34400  1.000 81.57000  ?  63   GLU R    OE2 1 
ATOM   4753 N N   . TYR C 3 85  ? 42.28300 38.04000 59.59800  1.000 56.87000  ?  64   TYR R    N   1 
ATOM   4754 C CA  . TYR C 3 85  ? 41.46900 37.28100 58.66500  1.000 58.19000  ?  64   TYR R    CA  1 
ATOM   4755 C C   . TYR C 3 85  ? 41.15700 38.17100 57.45400  1.000 63.55000  ?  64   TYR R    C   1 
ATOM   4756 O O   . TYR C 3 85  ? 40.01300 38.54800 57.21000  1.000 65.99000  ?  64   TYR R    O   1 
ATOM   4757 C CB  . TYR C 3 85  ? 40.18500 36.84200 59.35200  1.000 57.48000  ?  64   TYR R    CB  1 
ATOM   4758 C CG  . TYR C 3 85  ? 40.23400 35.63700 60.27000  1.000 55.32000  ?  64   TYR R    CG  1 
ATOM   4759 C CD1 . TYR C 3 85  ? 40.24800 34.37300 59.76900  1.000 50.31000  ?  64   TYR R    CD1 1 
ATOM   4760 C CD2 . TYR C 3 85  ? 40.16900 35.79100 61.66800  1.000 66.30000  ?  64   TYR R    CD2 1 
ATOM   4761 C CE1 . TYR C 3 85  ? 40.25500 33.29300 60.58900  1.000 57.58000  ?  64   TYR R    CE1 1 
ATOM   4762 C CE2 . TYR C 3 85  ? 40.16500 34.68900 62.53600  1.000 59.23000  ?  64   TYR R    CE2 1 
ATOM   4763 C CZ  . TYR C 3 85  ? 40.20300 33.43900 61.97600  1.000 61.32000  ?  64   TYR R    CZ  1 
ATOM   4764 O OH  . TYR C 3 85  ? 40.18800 32.31200 62.76000  1.000 63.79000  ?  64   TYR R    OH  1 
ATOM   4765 N N   . SER C 3 86  ? 42.20200 38.49600 56.67100  1.000 66.63000  ?  65   SER R    N   1 
ATOM   4766 C CA  . SER C 3 86  ? 42.07500 39.49500 55.59500  1.000 61.80000  ?  65   SER R    CA  1 
ATOM   4767 C C   . SER C 3 86  ? 41.05500 39.07600 54.55100  1.000 59.52000  ?  65   SER R    C   1 
ATOM   4768 O O   . SER C 3 86  ? 40.29500 39.91700 54.07300  1.000 62.61000  ?  65   SER R    O   1 
ATOM   4769 C CB  . SER C 3 86  ? 43.42100 39.76800 54.92900  1.000 60.25000  ?  65   SER R    CB  1 
ATOM   4770 O OG  . SER C 3 86  ? 44.07500 38.56600 54.59500  1.000 64.64000  ?  65   SER R    OG  1 
ATOM   4771 N N   . ALA C 3 87  ? 41.00100 37.78600 54.19700  1.000 63.23000  ?  66   ALA R    N   1 
ATOM   4772 C CA  . ALA C 3 87  ? 40.11100 37.34200 53.12600  1.000 60.31000  ?  66   ALA R    CA  1 
ATOM   4773 C C   . ALA C 3 87  ? 38.64400 37.49800 53.47600  1.000 61.26000  ?  66   ALA R    C   1 
ATOM   4774 O O   . ALA C 3 87  ? 37.81600 37.55200 52.55900  1.000 64.78000  ?  66   ALA R    O   1 
ATOM   4775 C CB  . ALA C 3 87  ? 40.36900 35.88600 52.76400  1.000 59.55000  ?  66   ALA R    CB  1 
ATOM   4776 N N   . MET C 3 88  ? 38.31100 37.56400 54.77300  1.000 57.00000  ?  67   MET R    N   1 
ATOM   4777 C CA  . MET C 3 88  ? 36.95000 37.64200 55.28600  1.000 55.04000  ?  67   MET R    CA  1 
ATOM   4778 C C   . MET C 3 88  ? 36.35200 39.04700 55.19400  1.000 61.31000  ?  67   MET R    C   1 
ATOM   4779 O O   . MET C 3 88  ? 35.13600 39.23000 55.37100  1.000 57.48000  ?  67   MET R    O   1 
ATOM   4780 C CB  . MET C 3 88  ? 36.96700 37.16600 56.72700  1.000 56.38000  ?  67   MET R    CB  1 
ATOM   4781 C CG  . MET C 3 88  ? 35.91700 36.17500 57.12000  1.000 59.85000  ?  67   MET R    CG  1 
ATOM   4782 S SD  . MET C 3 88  ? 36.48500 35.19400 58.50900  1.000 63.12000  ?  67   MET R    SD  1 
ATOM   4783 C CE  . MET C 3 88  ? 36.84600 33.61000 57.69900  1.000 59.97000  ?  67   MET R    CE  1 
ATOM   4784 N N   . ARG C 3 89  ? 37.18300 40.03800 54.89900  1.000 62.04000  ?  68   ARG R    N   1 
ATOM   4785 C CA  . ARG C 3 89  ? 36.75200 41.42700 54.89700  1.000 61.53000  ?  68   ARG R    CA  1 
ATOM   4786 C C   . ARG C 3 89  ? 35.60500 41.67200 53.90000  1.000 66.49000  ?  68   ARG R    C   1 
ATOM   4787 O O   . ARG C 3 89  ? 34.61600 42.33400 54.23500  1.000 59.68000  ?  68   ARG R    O   1 
ATOM   4788 C CB  . ARG C 3 89  ? 37.97900 42.28600 54.59000  1.000 67.07000  ?  68   ARG R    CB  1 
ATOM   4789 C CG  . ARG C 3 89  ? 37.86400 43.75200 54.89600  1.000 70.69000  ?  68   ARG R    CG  1 
ATOM   4790 C CD  . ARG C 3 89  ? 39.23200 44.39500 55.12400  1.000 73.14000  ?  68   ARG R    CD  1 
ATOM   4791 N NE  . ARG C 3 89  ? 40.30200 43.93800 54.23600  1.000 72.89000  ?  68   ARG R    NE  1 
ATOM   4792 C CZ  . ARG C 3 89  ? 41.40300 43.31600 54.65000  1.000 77.96000  ?  68   ARG R    CZ  1 
ATOM   4793 N NH1 . ARG C 3 89  ? 41.57900 42.99300 55.92700  1.000 78.68000  ?  68   ARG R    NH1 1 
ATOM   4794 N NH2 . ARG C 3 89  ? 42.36200 43.02500 53.76800  1.000 69.66000  ?  68   ARG R    NH2 1 
ATOM   4795 N N   . ASP C 3 90  ? 35.71700 41.15800 52.66000  1.000 70.02000  ?  69   ASP R    N   1 
ATOM   4796 C CA  . ASP C 3 90  ? 34.65800 41.38100 51.66500  1.000 69.33000  ?  69   ASP R    CA  1 
ATOM   4797 C C   . ASP C 3 90  ? 33.29400 40.88800 52.17100  1.000 72.01000  ?  69   ASP R    C   1 
ATOM   4798 O O   . ASP C 3 90  ? 32.28200 41.58700 52.04700  1.000 68.65000  ?  69   ASP R    O   1 
ATOM   4799 C CB  . ASP C 3 90  ? 34.99400 40.70100 50.32500  1.000 70.41000  ?  69   ASP R    CB  1 
ATOM   4800 C CG  . ASP C 3 90  ? 36.19000 41.34600 49.57700  1.000 83.98000  ?  69   ASP R    CG  1 
ATOM   4801 O OD1 . ASP C 3 90  ? 36.30400 42.59900 49.52600  1.000 86.17000  ?  69   ASP R    OD1 1 
ATOM   4802 O OD2 . ASP C 3 90  ? 36.97200 40.59100 48.94000  1.000 81.32000  ?  69   ASP R    OD2 1 
ATOM   4803 N N   . GLN C 3 91  ? 33.25300 39.68000 52.74700  1.000 71.61000  ?  70   GLN R    N   1 
ATOM   4804 C CA  . GLN C 3 91  ? 32.01700 39.14500 53.30800  1.000 68.39000  ?  70   GLN R    CA  1 
ATOM   4805 C C   . GLN C 3 91  ? 31.40200 40.07400 54.35400  1.000 72.19000  ?  70   GLN R    C   1 
ATOM   4806 O O   . GLN C 3 91  ? 30.23200 40.45200 54.24100  1.000 75.98000  ?  70   GLN R    O   1 
ATOM   4807 C CB  . GLN C 3 91  ? 32.27200 37.77300 53.91800  1.000 72.59000  ?  70   GLN R    CB  1 
ATOM   4808 C CG  . GLN C 3 91  ? 31.23300 37.39600 54.95000  1.000 71.68000  ?  70   GLN R    CG  1 
ATOM   4809 C CD  . GLN C 3 91  ? 31.26800 35.93100 55.32500  1.000 78.13000  ?  70   GLN R    CD  1 
ATOM   4810 O OE1 . GLN C 3 91  ? 31.97800 35.12500 54.72000  1.000 71.51000  ?  70   GLN R    OE1 1 
ATOM   4811 N NE2 . GLN C 3 91  ? 30.52000 35.58400 56.36300  1.000 89.58000  ?  70   GLN R    NE2 1 
ATOM   4812 N N   . TYR C 3 92  ? 32.16400 40.43400 55.39900  1.000 69.67000  ?  71   TYR R    N   1 
ATOM   4813 C CA  . TYR C 3 92  ? 31.61100 41.28100 56.46300  1.000 65.74000  ?  71   TYR R    CA  1 
ATOM   4814 C C   . TYR C 3 92  ? 31.11700 42.60500 55.89900  1.000 70.40000  ?  71   TYR R    C   1 
ATOM   4815 O O   . TYR C 3 92  ? 29.99700 43.03600 56.18800  1.000 77.02000  ?  71   TYR R    O   1 
ATOM   4816 C CB  . TYR C 3 92  ? 32.65800 41.56800 57.54300  1.000 62.95000  ?  71   TYR R    CB  1 
ATOM   4817 C CG  . TYR C 3 92  ? 32.99300 40.41900 58.45200  1.000 62.02000  ?  71   TYR R    CG  1 
ATOM   4818 C CD1 . TYR C 3 92  ? 32.05600 39.90100 59.32100  1.000 61.64000  ?  71   TYR R    CD1 1 
ATOM   4819 C CD2 . TYR C 3 92  ? 34.26100 39.85800 58.44200  1.000 56.58000  ?  71   TYR R    CD2 1 
ATOM   4820 C CE1 . TYR C 3 92  ? 32.36000 38.84200 60.14400  1.000 62.81000  ?  71   TYR R    CE1 1 
ATOM   4821 C CE2 . TYR C 3 92  ? 34.57500 38.79300 59.25200  1.000 61.64000  ?  71   TYR R    CE2 1 
ATOM   4822 C CZ  . TYR C 3 92  ? 33.61500 38.28400 60.11000  1.000 64.36000  ?  71   TYR R    CZ  1 
ATOM   4823 O OH  . TYR C 3 92  ? 33.90400 37.22700 60.95500  1.000 60.63000  ?  71   TYR R    OH  1 
ATOM   4824 N N   . MET C 3 93  ? 31.95200 43.27300 55.09200  1.000 68.88000  ?  72   MET R    N   1 
ATOM   4825 C CA  . MET C 3 93  ? 31.61000 44.60100 54.60200  1.000 64.70000  ?  72   MET R    CA  1 
ATOM   4826 C C   . MET C 3 93  ? 30.30400 44.57700 53.86100  1.000 65.73000  ?  72   MET R    C   1 
ATOM   4827 O O   . MET C 3 93  ? 29.57300 45.56500 53.86300  1.000 66.87000  ?  72   MET R    O   1 
ATOM   4828 C CB  . MET C 3 93  ? 32.69400 45.12200 53.67600  1.000 63.06000  ?  72   MET R    CB  1 
ATOM   4829 C CG  . MET C 3 93  ? 33.87700 45.66500 54.38300  1.000 65.48000  ?  72   MET R    CG  1 
ATOM   4830 S SD  . MET C 3 93  ? 35.13300 46.12200 53.20300  1.000 71.40000  ?  72   MET R    SD  1 
ATOM   4831 C CE  . MET C 3 93  ? 36.38300 46.83400 54.23000  1.000 67.75000  ?  72   MET R    CE  1 
ATOM   4832 N N   . ARG C 3 94  ? 29.99600 43.45100 53.22300  1.000 71.01000  ?  73   ARG R    N   1 
ATOM   4833 C CA  . ARG C 3 94  ? 28.81900 43.38000 52.36600  1.000 76.29000  ?  73   ARG R    CA  1 
ATOM   4834 C C   . ARG C 3 94  ? 27.53800 43.52600 53.17100  1.000 77.75000  ?  73   ARG R    C   1 
ATOM   4835 O O   . ARG C 3 94  ? 26.54700 44.07000 52.65800  1.000 76.12000  ?  73   ARG R    O   1 
ATOM   4836 C CB  . ARG C 3 94  ? 28.82800 42.06500 51.58100  1.000 73.88000  ?  73   ARG R    CB  1 
ATOM   4837 C CG  . ARG C 3 94  ? 27.61200 41.83100 50.73100  1.000 71.84000  ?  73   ARG R    CG  1 
ATOM   4838 C CD  . ARG C 3 94  ? 27.84700 40.75700 49.66700  1.000 74.55000  ?  73   ARG R    CD  1 
ATOM   4839 N NE  . ARG C 3 94  ? 28.67100 41.25100 48.57100  1.000 72.86000  ?  73   ARG R    NE  1 
ATOM   4840 C CZ  . ARG C 3 94  ? 29.84900 40.74300 48.24100  1.000 72.89000  ?  73   ARG R    CZ  1 
ATOM   4841 N NH1 . ARG C 3 94  ? 30.33200 39.67100 48.85500  1.000 70.25000  ?  73   ARG R    NH1 1 
ATOM   4842 N NH2 . ARG C 3 94  ? 30.55700 41.32100 47.27000  1.000 70.39000  ?  73   ARG R    NH2 1 
ATOM   4843 N N   . THR C 3 95  ? 27.55100 43.09300 54.44500  1.000 73.76000  ?  74   THR R    N   1 
ATOM   4844 C CA  . THR C 3 95  ? 26.31900 43.05700 55.23200  1.000 74.76000  ?  74   THR R    CA  1 
ATOM   4845 C C   . THR C 3 95  ? 25.81700 44.43400 55.61800  1.000 73.19000  ?  74   THR R    C   1 
ATOM   4846 O O   . THR C 3 95  ? 24.73200 44.52800 56.19800  1.000 74.90000  ?  74   THR R    O   1 
ATOM   4847 C CB  . THR C 3 95  ? 26.49100 42.26600 56.51900  1.000 70.77000  ?  74   THR R    CB  1 
ATOM   4848 O OG1 . THR C 3 95  ? 27.08700 43.11300 57.51000  1.000 73.26000  ?  74   THR R    OG1 1 
ATOM   4849 C CG2 . THR C 3 95  ? 27.37100 41.06700 56.27800  1.000 73.96000  ?  74   THR R    CG2 1 
ATOM   4850 N N   . GLY C 3 96  ? 26.56400 45.48900 55.32900  1.000 68.73000  ?  75   GLY R    N   1 
ATOM   4851 C CA  . GLY C 3 96  ? 26.19800 46.78500 55.85100  1.000 72.10000  ?  75   GLY R    CA  1 
ATOM   4852 C C   . GLY C 3 96  ? 25.96600 47.84000 54.79800  1.000 70.46000  ?  75   GLY R    C   1 
ATOM   4853 O O   . GLY C 3 96  ? 26.53500 47.78500 53.70700  1.000 66.22000  ?  75   GLY R    O   1 
ATOM   4854 N N   . GLU C 3 97  ? 25.15900 48.83900 55.14100  1.000 71.70000  ?  76   GLU R    N   1 
ATOM   4855 C CA  . GLU C 3 97  ? 24.78100 49.86900 54.19500  1.000 74.30000  ?  76   GLU R    CA  1 
ATOM   4856 C C   . GLU C 3 97  ? 25.39600 51.22900 54.47200  1.000 75.63000  ?  76   GLU R    C   1 
ATOM   4857 O O   . GLU C 3 97  ? 25.35600 52.08800 53.58200  1.000 79.82000  ?  76   GLU R    O   1 
ATOM   4858 C CB  . GLU C 3 97  ? 23.25300 49.97900 54.11600  1.000 79.89000  ?  76   GLU R    CB  1 
ATOM   4859 C CG  . GLU C 3 97  ? 22.55200 50.22500 55.41500  1.000 85.60000  ?  76   GLU R    CG  1 
ATOM   4860 C CD  . GLU C 3 97  ? 21.04200 50.30000 55.22900  1.000 95.96000  ?  76   GLU R    CD  1 
ATOM   4861 O OE1 . GLU C 3 97  ? 20.61300 50.75200 54.13400  1.000 100.28000 ?  76   GLU R    OE1 1 
ATOM   4862 O OE2 . GLU C 3 97  ? 20.29500 49.87300 56.15800  1.000 90.85000  ?  76   GLU R    OE2 1 
ATOM   4863 N N   . GLY C 3 98  ? 25.99600 51.44500 55.64300  1.000 72.12000  ?  77   GLY R    N   1 
ATOM   4864 C CA  . GLY C 3 98  ? 26.87000 52.58000 55.84400  1.000 71.39000  ?  77   GLY R    CA  1 
ATOM   4865 C C   . GLY C 3 98  ? 28.16800 52.13800 56.49600  1.000 73.87000  ?  77   GLY R    C   1 
ATOM   4866 O O   . GLY C 3 98  ? 28.23800 51.07500 57.12300  1.000 77.24000  ?  77   GLY R    O   1 
ATOM   4867 N N   . PHE C 3 99  ? 29.20100 52.97500 56.36600  1.000 71.30000  ?  78   PHE R    N   1 
ATOM   4868 C CA  . PHE C 3 99  ? 30.50800 52.59200 56.89500  1.000 68.73000  ?  78   PHE R    CA  1 
ATOM   4869 C C   . PHE C 3 99  ? 31.17400 53.72900 57.65600  1.000 65.80000  ?  78   PHE R    C   1 
ATOM   4870 O O   . PHE C 3 99  ? 31.31400 54.83000 57.12300  1.000 70.03000  ?  78   PHE R    O   1 
ATOM   4871 C CB  . PHE C 3 99  ? 31.39400 52.10700 55.74900  1.000 64.24000  ?  78   PHE R    CB  1 
ATOM   4872 C CG  . PHE C 3 99  ? 30.82300 50.93400 55.05800  1.000 63.02000  ?  78   PHE R    CG  1 
ATOM   4873 C CD1 . PHE C 3 99  ? 31.03400 49.67000 55.55100  1.000 62.02000  ?  78   PHE R    CD1 1 
ATOM   4874 C CD2 . PHE C 3 99  ? 29.98100 51.10000 53.97300  1.000 66.46000  ?  78   PHE R    CD2 1 
ATOM   4875 C CE1 . PHE C 3 99  ? 30.47100 48.58600 54.93600  1.000 66.67000  ?  78   PHE R    CE1 1 
ATOM   4876 C CE2 . PHE C 3 99  ? 29.40500 50.01800 53.35100  1.000 65.36000  ?  78   PHE R    CE2 1 
ATOM   4877 C CZ  . PHE C 3 99  ? 29.64600 48.76300 53.83200  1.000 66.87000  ?  78   PHE R    CZ  1 
ATOM   4878 N N   . LEU C 3 100 ? 31.58900 53.46700 58.89300  1.000 60.11000  ?  79   LEU R    N   1 
ATOM   4879 C CA  . LEU C 3 100 ? 32.55700 54.33100 59.56000  1.000 60.85000  ?  79   LEU R    CA  1 
ATOM   4880 C C   . LEU C 3 100 ? 33.95800 53.84900 59.19800  1.000 59.85000  ?  79   LEU R    C   1 
ATOM   4881 O O   . LEU C 3 100 ? 34.36200 52.74800 59.57200  1.000 62.06000  ?  79   LEU R    O   1 
ATOM   4882 C CB  . LEU C 3 100 ? 32.37100 54.34900 61.07200  1.000 62.39000  ?  79   LEU R    CB  1 
ATOM   4883 C CG  . LEU C 3 100 ? 31.46200 55.37200 61.77500  1.000 68.40000  ?  79   LEU R    CG  1 
ATOM   4884 C CD1 . LEU C 3 100 ? 30.04700 55.07500 61.58300  1.000 70.89000  ?  79   LEU R    CD1 1 
ATOM   4885 C CD2 . LEU C 3 100 ? 31.74100 55.43000 63.28300  1.000 75.95000  ?  79   LEU R    CD2 1 
ATOM   4886 N N   . CYS C 3 101 ? 34.69100 54.66000 58.45300  1.000 57.55000  ?  80   CYS R    N   1 
ATOM   4887 C CA  . CYS C 3 101 ? 36.08100 54.37700 58.11800  1.000 58.43000  ?  80   CYS R    CA  1 
ATOM   4888 C C   . CYS C 3 101 ? 36.92700 55.08400 59.15600  1.000 62.63000  ?  80   CYS R    C   1 
ATOM   4889 O O   . CYS C 3 101 ? 37.13400 56.29300 59.04200  1.000 64.22000  ?  80   CYS R    O   1 
ATOM   4890 C CB  . CYS C 3 101 ? 36.43000 54.87600 56.72100  1.000 58.73000  ?  80   CYS R    CB  1 
ATOM   4891 S SG  . CYS C 3 101 ? 35.77700 53.84000 55.41200  1.000 67.42000  ?  80   CYS R    SG  1 
ATOM   4892 N N   . VAL C 3 102 ? 37.42500 54.32200 60.17700  1.000 58.45000  ?  81   VAL R    N   1 
ATOM   4893 C CA  . VAL C 3 102 ? 38.08400 54.88400 61.35900  1.000 51.46000  ?  81   VAL R    CA  1 
ATOM   4894 C C   . VAL C 3 102 ? 39.58900 54.80600 61.20000  1.000 57.29000  ?  81   VAL R    C   1 
ATOM   4895 O O   . VAL C 3 102 ? 40.11900 53.80000 60.71000  1.000 57.39000  ?  81   VAL R    O   1 
ATOM   4896 C CB  . VAL C 3 102 ? 37.64100 54.16600 62.64700  1.000 55.72000  ?  81   VAL R    CB  1 
ATOM   4897 C CG1 . VAL C 3 102 ? 38.38900 54.72000 63.85400  1.000 58.20000  ?  81   VAL R    CG1 1 
ATOM   4898 C CG2 . VAL C 3 102 ? 36.13900 54.29200 62.86200  1.000 56.27000  ?  81   VAL R    CG2 1 
ATOM   4899 N N   . PHE C 3 103 ? 40.28600 55.86600 61.62200  1.000 61.13000  ?  82   PHE R    N   1 
ATOM   4900 C CA  . PHE C 3 103 ? 41.73400 55.82200 61.79900  1.000 64.30000  ?  82   PHE R    CA  1 
ATOM   4901 C C   . PHE C 3 103 ? 42.09100 56.47300 63.13100  1.000 64.92000  ?  82   PHE R    C   1 
ATOM   4902 O O   . PHE C 3 103 ? 41.30300 57.22200 63.71300  1.000 64.82000  ?  82   PHE R    O   1 
ATOM   4903 C CB  . PHE C 3 103 ? 42.48200 56.48600 60.62300  1.000 64.78000  ?  82   PHE R    CB  1 
ATOM   4904 C CG  . PHE C 3 103 ? 42.34800 57.98400 60.56200  1.000 67.47000  ?  82   PHE R    CG  1 
ATOM   4905 C CD1 . PHE C 3 103 ? 41.30200 58.56900 59.87200  1.000 62.72000  ?  82   PHE R    CD1 1 
ATOM   4906 C CD2 . PHE C 3 103 ? 43.27500 58.81200 61.19800  1.000 70.80000  ?  82   PHE R    CD2 1 
ATOM   4907 C CE1 . PHE C 3 103 ? 41.17500 59.94600 59.82100  1.000 65.89000  ?  82   PHE R    CE1 1 
ATOM   4908 C CE2 . PHE C 3 103 ? 43.15400 60.18900 61.15400  1.000 68.46000  ?  82   PHE R    CE2 1 
ATOM   4909 C CZ  . PHE C 3 103 ? 42.09900 60.75700 60.46400  1.000 67.75000  ?  82   PHE R    CZ  1 
ATOM   4910 N N   . ALA C 3 104 ? 43.27200 56.14500 63.63400  1.000 64.52000  ?  83   ALA R    N   1 
ATOM   4911 C CA  . ALA C 3 104 ? 43.77800 56.77500 64.84200  1.000 68.54000  ?  83   ALA R    CA  1 
ATOM   4912 C C   . ALA C 3 104 ? 44.56700 58.01800 64.47200  1.000 71.86000  ?  83   ALA R    C   1 
ATOM   4913 O O   . ALA C 3 104 ? 45.18400 58.08500 63.41000  1.000 77.46000  ?  83   ALA R    O   1 
ATOM   4914 C CB  . ALA C 3 104 ? 44.66500 55.81500 65.62700  1.000 74.49000  ?  83   ALA R    CB  1 
ATOM   4915 N N   . ILE C 3 105 ? 44.55300 59.00500 65.35300  1.000 73.03000  ?  84   ILE R    N   1 
ATOM   4916 C CA  . ILE C 3 105 ? 45.25500 60.25200 65.06400  1.000 73.81000  ?  84   ILE R    CA  1 
ATOM   4917 C C   . ILE C 3 105 ? 46.74100 60.18300 65.41600  1.000 72.43000  ?  84   ILE R    C   1 
ATOM   4918 O O   . ILE C 3 105 ? 47.56100 60.85500 64.79500  1.000 72.22000  ?  84   ILE R    O   1 
ATOM   4919 C CB  . ILE C 3 105 ? 44.55800 61.40300 65.79500  1.000 73.36000  ?  84   ILE R    CB  1 
ATOM   4920 C CG1 . ILE C 3 105 ? 43.20800 61.63900 65.16100  1.000 72.20000  ?  84   ILE R    CG1 1 
ATOM   4921 C CG2 . ILE C 3 105 ? 45.36300 62.65200 65.73000  1.000 75.62000  ?  84   ILE R    CG2 1 
ATOM   4922 C CD1 . ILE C 3 105 ? 42.49900 62.75500 65.82000  1.000 78.64000  ?  84   ILE R    CD1 1 
ATOM   4923 N N   . ASN C 3 106 ? 47.11900 59.39600 66.40100  1.000 74.17000  ?  85   ASN R    N   1 
ATOM   4924 C CA  . ASN C 3 106 ? 48.53300 59.24400 66.65900  1.000 76.05000  ?  85   ASN R    CA  1 
ATOM   4925 C C   . ASN C 3 106 ? 49.18300 58.31200 65.66000  1.000 77.81000  ?  85   ASN R    C   1 
ATOM   4926 O O   . ASN C 3 106 ? 50.41100 58.24100 65.60700  1.000 84.09000  ?  85   ASN R    O   1 
ATOM   4927 C CB  . ASN C 3 106 ? 48.73900 58.72800 68.07700  1.000 82.91000  ?  85   ASN R    CB  1 
ATOM   4928 C CG  . ASN C 3 106 ? 47.83200 57.56700 68.38900  1.000 90.82000  ?  85   ASN R    CG  1 
ATOM   4929 O OD1 . ASN C 3 106 ? 46.64900 57.76200 68.67000  1.000 93.92000  ?  85   ASN R    OD1 1 
ATOM   4930 N ND2 . ASN C 3 106 ? 48.36200 56.34600 68.30900  1.000 94.85000  ?  85   ASN R    ND2 1 
ATOM   4931 N N   . ASN C 3 107 ? 48.39600 57.60300 64.87200  1.000 76.05000  ?  86   ASN R    N   1 
ATOM   4932 C CA  . ASN C 3 107 ? 48.90100 56.59100 63.95300  1.000 76.31000  ?  86   ASN R    CA  1 
ATOM   4933 C C   . ASN C 3 107 ? 48.82100 57.13500 62.53600  1.000 71.33000  ?  86   ASN R    C   1 
ATOM   4934 O O   . ASN C 3 107 ? 47.72200 57.29500 62.00700  1.000 71.76000  ?  86   ASN R    O   1 
ATOM   4935 C CB  . ASN C 3 107 ? 48.10000 55.29900 64.10200  1.000 74.05000  ?  86   ASN R    CB  1 
ATOM   4936 C CG  . ASN C 3 107 ? 48.60800 54.19100 63.19600  1.000 78.72000  ?  86   ASN R    CG  1 
ATOM   4937 O OD1 . ASN C 3 107 ? 48.95000 54.42900 62.03600  1.000 75.43000  ?  86   ASN R    OD1 1 
ATOM   4938 N ND2 . ASN C 3 107 ? 48.68600 52.97600 63.73000  1.000 81.55000  ?  86   ASN R    ND2 1 
ATOM   4939 N N   . THR C 3 108 ? 49.97800 57.39300 61.90900  1.000 70.45000  ?  87   THR R    N   1 
ATOM   4940 C CA  . THR C 3 108 ? 49.92100 57.94400 60.55500  1.000 73.60000  ?  87   THR R    CA  1 
ATOM   4941 C C   . THR C 3 108 ? 49.64400 56.86000 59.52200  1.000 73.46000  ?  87   THR R    C   1 
ATOM   4942 O O   . THR C 3 108 ? 48.81900 57.06700 58.62100  1.000 66.67000  ?  87   THR R    O   1 
ATOM   4943 C CB  . THR C 3 108 ? 51.20600 58.68200 60.19700  1.000 71.62000  ?  87   THR R    CB  1 
ATOM   4944 O OG1 . THR C 3 108 ? 51.64200 59.42500 61.33500  1.000 81.10000  ?  87   THR R    OG1 1 
ATOM   4945 C CG2 . THR C 3 108 ? 50.94600 59.64800 59.06000  1.000 68.63000  ?  87   THR R    CG2 1 
ATOM   4946 N N   . LYS C 3 109 ? 50.31800 55.70600 59.66000  1.000 74.57000  ?  88   LYS R    N   1 
ATOM   4947 C CA  . LYS C 3 109 ? 50.07400 54.55300 58.79600  1.000 67.64000  ?  88   LYS R    CA  1 
ATOM   4948 C C   . LYS C 3 109 ? 48.58700 54.32700 58.61400  1.000 68.97000  ?  88   LYS R    C   1 
ATOM   4949 O O   . LYS C 3 109 ? 48.11700 54.16200 57.48900  1.000 73.10000  ?  88   LYS R    O   1 
ATOM   4950 C CB  . LYS C 3 109 ? 50.71900 53.30400 59.39500  1.000 68.75000  ?  88   LYS R    CB  1 
ATOM   4951 C CG  . LYS C 3 109 ? 51.70400 52.53400 58.51700  1.000 79.52000  ?  88   LYS R    CG  1 
ATOM   4952 C CD  . LYS C 3 109 ? 51.04800 51.45800 57.63100  1.000 97.13000  ?  88   LYS R    CD  1 
ATOM   4953 C CE  . LYS C 3 109 ? 52.10500 50.60900 56.86900  1.000 105.18000 ?  88   LYS R    CE  1 
ATOM   4954 N NZ  . LYS C 3 109 ? 51.51400 49.67800 55.84500  1.000 104.62000 ?  88   LYS R    NZ  1 
ATOM   4955 N N   . SER C 3 110 ? 47.81800 54.37000 59.70700  1.000 70.61000  ?  89   SER R    N   1 
ATOM   4956 C CA  . SER C 3 110 ? 46.39500 54.05700 59.62700  1.000 66.63000  ?  89   SER R    CA  1 
ATOM   4957 C C   . SER C 3 110 ? 45.65200 55.09000 58.81200  1.000 66.60000  ?  89   SER R    C   1 
ATOM   4958 O O   . SER C 3 110 ? 44.70000 54.75300 58.10100  1.000 68.80000  ?  89   SER R    O   1 
ATOM   4959 C CB  . SER C 3 110 ? 45.77900 53.96900 61.01500  1.000 60.40000  ?  89   SER R    CB  1 
ATOM   4960 O OG  . SER C 3 110 ? 45.82200 55.22600 61.62800  1.000 63.35000  ?  89   SER R    OG  1 
ATOM   4961 N N   . PHE C 3 111 ? 46.06000 56.34900 58.91000  1.000 66.58000  ?  90   PHE R    N   1 
ATOM   4962 C CA  . PHE C 3 111 ? 45.47300 57.36300 58.05200  1.000 66.17000  ?  90   PHE R    CA  1 
ATOM   4963 C C   . PHE C 3 111 ? 45.77800 57.08600 56.58400  1.000 71.33000  ?  90   PHE R    C   1 
ATOM   4964 O O   . PHE C 3 111 ? 44.88700 57.18000 55.72700  1.000 70.76000  ?  90   PHE R    O   1 
ATOM   4965 C CB  . PHE C 3 111 ? 45.97800 58.73300 58.46600  1.000 66.73000  ?  90   PHE R    CB  1 
ATOM   4966 C CG  . PHE C 3 111 ? 45.43600 59.83300 57.63900  1.000 64.89000  ?  90   PHE R    CG  1 
ATOM   4967 C CD1 . PHE C 3 111 ? 44.11100 60.13700 57.67100  1.000 70.49000  ?  90   PHE R    CD1 1 
ATOM   4968 C CD2 . PHE C 3 111 ? 46.25500 60.57600 56.84100  1.000 67.38000  ?  90   PHE R    CD2 1 
ATOM   4969 C CE1 . PHE C 3 111 ? 43.60500 61.15000 56.90200  1.000 74.09000  ?  90   PHE R    CE1 1 
ATOM   4970 C CE2 . PHE C 3 111 ? 45.75000 61.59300 56.08500  1.000 71.88000  ?  90   PHE R    CE2 1 
ATOM   4971 C CZ  . PHE C 3 111 ? 44.42400 61.87700 56.11600  1.000 71.57000  ?  90   PHE R    CZ  1 
ATOM   4972 N N   . GLU C 3 112 ? 47.03100 56.72700 56.28100  1.000 70.44000  ?  91   GLU R    N   1 
ATOM   4973 C CA  . GLU C 3 112 ? 47.39400 56.38700 54.91500  1.000 65.56000  ?  91   GLU R    CA  1 
ATOM   4974 C C   . GLU C 3 112 ? 46.61000 55.18700 54.42300  1.000 70.35000  ?  91   GLU R    C   1 
ATOM   4975 O O   . GLU C 3 112 ? 46.10100 55.19600 53.29800  1.000 82.61000  ?  91   GLU R    O   1 
ATOM   4976 C CB  . GLU C 3 112 ? 48.89200 56.14200 54.81700  1.000 69.38000  ?  91   GLU R    CB  1 
ATOM   4977 C CG  . GLU C 3 112 ? 49.70900 57.32900 55.34700  1.000 78.83000  ?  91   GLU R    CG  1 
ATOM   4978 C CD  . GLU C 3 112 ? 51.21000 57.02400 55.55100  1.000 88.15000  ?  91   GLU R    CD  1 
ATOM   4979 O OE1 . GLU C 3 112 ? 51.63600 55.84200 55.39000  1.000 80.66000  ?  91   GLU R    OE1 1 
ATOM   4980 O OE2 . GLU C 3 112 ? 51.94900 57.98800 55.89600  1.000 88.70000  ?  91   GLU R    OE2 1 
ATOM   4981 N N   . ASP C 3 113 ? 46.45500 54.17000 55.25900  1.000 65.07000  ?  92   ASP R    N   1 
ATOM   4982 C CA  . ASP C 3 113 ? 45.68100 52.98900 54.90100  1.000 67.47000  ?  92   ASP R    CA  1 
ATOM   4983 C C   . ASP C 3 113 ? 44.20200 53.26200 54.72400  1.000 67.76000  ?  92   ASP R    C   1 
ATOM   4984 O O   . ASP C 3 113 ? 43.46000 52.33000 54.43900  1.000 69.52000  ?  92   ASP R    O   1 
ATOM   4985 C CB  . ASP C 3 113 ? 45.83900 51.90800 55.96700  1.000 74.37000  ?  92   ASP R    CB  1 
ATOM   4986 C CG  . ASP C 3 113 ? 47.22000 51.23300 55.93400  1.000 92.86000  ?  92   ASP R    CG  1 
ATOM   4987 O OD1 . ASP C 3 113 ? 48.12800 51.71100 55.17600  1.000 90.16000  ?  92   ASP R    OD1 1 
ATOM   4988 O OD2 . ASP C 3 113 ? 47.39700 50.24900 56.71100  1.000 93.64000  ?  92   ASP R    OD2 1 
ATOM   4989 N N   . ILE C 3 114 ? 43.72200 54.48600 54.89400  1.000 73.06000  ?  93   ILE R    N   1 
ATOM   4990 C CA  . ILE C 3 114 ? 42.27300 54.67900 54.86900  1.000 75.29000  ?  93   ILE R    CA  1 
ATOM   4991 C C   . ILE C 3 114 ? 41.73100 54.50600 53.46100  1.000 72.36000  ?  93   ILE R    C   1 
ATOM   4992 O O   . ILE C 3 114 ? 40.66100 53.92300 53.27300  1.000 71.84000  ?  93   ILE R    O   1 
ATOM   4993 C CB  . ILE C 3 114 ? 41.86800 56.03800 55.48200  1.000 70.35000  ?  93   ILE R    CB  1 
ATOM   4994 C CG1 . ILE C 3 114 ? 41.93900 55.96200 56.99700  1.000 69.50000  ?  93   ILE R    CG1 1 
ATOM   4995 C CG2 . ILE C 3 114 ? 40.42400 56.35000 55.19600  1.000 64.21000  ?  93   ILE R    CG2 1 
ATOM   4996 C CD1 . ILE C 3 114 ? 40.86500 55.06500 57.57600  1.000 66.22000  ?  93   ILE R    CD1 1 
ATOM   4997 N N   . HIS C 3 115 ? 42.45300 54.97600 52.44900  1.000 68.89000  ?  94   HIS R    N   1 
ATOM   4998 C CA  . HIS C 3 115 ? 41.85400 54.95800 51.12000  1.000 78.00000  ?  94   HIS R    CA  1 
ATOM   4999 C C   . HIS C 3 115 ? 41.59100 53.53400 50.64600  1.000 73.96000  ?  94   HIS R    C   1 
ATOM   5000 O O   . HIS C 3 115 ? 40.60800 53.28300 49.94100  1.000 70.89000  ?  94   HIS R    O   1 
ATOM   5001 C CB  . HIS C 3 115 ? 42.73800 55.73600 50.14500  1.000 86.90000  ?  94   HIS R    CB  1 
ATOM   5002 C CG  . HIS C 3 115 ? 44.03000 55.06700 49.82200  1.000 87.04000  ?  94   HIS R    CG  1 
ATOM   5003 N ND1 . HIS C 3 115 ? 45.11500 55.10100 50.67600  1.000 88.97000  ?  94   HIS R    ND1 1 
ATOM   5004 C CD2 . HIS C 3 115 ? 44.44000 54.41300 48.71000  1.000 84.96000  ?  94   HIS R    CD2 1 
ATOM   5005 C CE1 . HIS C 3 115 ? 46.12500 54.44800 50.12600  1.000 88.14000  ?  94   HIS R    CE1 1 
ATOM   5006 N NE2 . HIS C 3 115 ? 45.74200 54.02600 48.93100  1.000 91.59000  ?  94   HIS R    NE2 1 
ATOM   5007 N N   . HIS C 3 116 ? 42.42100 52.59300 51.08800  1.000 72.15000  ?  95   HIS R    N   1 
ATOM   5008 C CA  . HIS C 3 116 ? 42.26800 51.18600 50.74000  1.000 71.61000  ?  95   HIS R    CA  1 
ATOM   5009 C C   . HIS C 3 116 ? 40.93000 50.62900 51.20800  1.000 74.64000  ?  95   HIS R    C   1 
ATOM   5010 O O   . HIS C 3 116 ? 40.27000 49.88000 50.47400  1.000 70.05000  ?  95   HIS R    O   1 
ATOM   5011 C CB  . HIS C 3 116 ? 43.43100 50.42600 51.35100  1.000 71.72000  ?  95   HIS R    CB  1 
ATOM   5012 C CG  . HIS C 3 116 ? 44.71500 50.66500 50.63900  1.000 76.88000  ?  95   HIS R    CG  1 
ATOM   5013 N ND1 . HIS C 3 116 ? 45.93800 50.31700 51.16500  1.000 81.89000  ?  95   HIS R    ND1 1 
ATOM   5014 C CD2 . HIS C 3 116 ? 44.95800 51.13800 49.39400  1.000 80.22000  ?  95   HIS R    CD2 1 
ATOM   5015 C CE1 . HIS C 3 116 ? 46.88700 50.63500 50.30100  1.000 93.46000  ?  95   HIS R    CE1 1 
ATOM   5016 N NE2 . HIS C 3 116 ? 46.31900 51.12300 49.21200  1.000 88.56000  ?  95   HIS R    NE2 1 
ATOM   5017 N N   . TYR C 3 117 ? 40.51100 50.98100 52.43300  1.000 75.70000  ?  96   TYR R    N   1 
ATOM   5018 C CA  . TYR C 3 117 ? 39.19700 50.56000 52.91300  1.000 68.91000  ?  96   TYR R    CA  1 
ATOM   5019 C C   . TYR C 3 117 ? 38.09300 51.16600 52.05500  1.000 69.40000  ?  96   TYR R    C   1 
ATOM   5020 O O   . TYR C 3 117 ? 37.16600 50.46500 51.64500  1.000 71.12000  ?  96   TYR R    O   1 
ATOM   5021 C CB  . TYR C 3 117 ? 39.02500 50.93800 54.38100  1.000 68.73000  ?  96   TYR R    CB  1 
ATOM   5022 C CG  . TYR C 3 117 ? 39.96800 50.14800 55.26600  1.000 74.29000  ?  96   TYR R    CG  1 
ATOM   5023 C CD1 . TYR C 3 117 ? 39.59200 48.91900 55.79400  1.000 70.48000  ?  96   TYR R    CD1 1 
ATOM   5024 C CD2 . TYR C 3 117 ? 41.22800 50.64400 55.59200  1.000 73.04000  ?  96   TYR R    CD2 1 
ATOM   5025 C CE1 . TYR C 3 117 ? 40.45300 48.18400 56.58300  1.000 68.09000  ?  96   TYR R    CE1 1 
ATOM   5026 C CE2 . TYR C 3 117 ? 42.09500 49.92200 56.40300  1.000 67.68000  ?  96   TYR R    CE2 1 
ATOM   5027 C CZ  . TYR C 3 117 ? 41.70500 48.68700 56.88600  1.000 69.13000  ?  96   TYR R    CZ  1 
ATOM   5028 O OH  . TYR C 3 117 ? 42.56700 47.93300 57.66700  1.000 72.33000  ?  96   TYR R    OH  1 
ATOM   5029 N N   . ARG C 3 118 ? 38.20400 52.45700 51.72300  1.000 65.53000  ?  97   ARG R    N   1 
ATOM   5030 C CA  . ARG C 3 118 ? 37.21500 53.06100 50.84000  1.000 68.28000  ?  97   ARG R    CA  1 
ATOM   5031 C C   . ARG C 3 118 ? 37.21300 52.39200 49.47400  1.000 75.15000  ?  97   ARG R    C   1 
ATOM   5032 O O   . ARG C 3 118 ? 36.13900 52.17000 48.89400  1.000 75.54000  ?  97   ARG R    O   1 
ATOM   5033 C CB  . ARG C 3 118 ? 37.45300 54.56100 50.68800  1.000 73.80000  ?  97   ARG R    CB  1 
ATOM   5034 C CG  . ARG C 3 118 ? 36.59900 55.18400 49.57300  1.000 79.98000  ?  97   ARG R    CG  1 
ATOM   5035 C CD  . ARG C 3 118 ? 36.45900 56.69200 49.68800  1.000 80.47000  ?  97   ARG R    CD  1 
ATOM   5036 N NE  . ARG C 3 118 ? 35.95200 57.26000 48.44500  1.000 85.84000  ?  97   ARG R    NE  1 
ATOM   5037 C CZ  . ARG C 3 118 ? 34.68200 57.57800 48.22300  1.000 90.08000  ?  97   ARG R    CZ  1 
ATOM   5038 N NH1 . ARG C 3 118 ? 33.75700 57.44300 49.16500  1.000 83.70000  ?  97   ARG R    NH1 1 
ATOM   5039 N NH2 . ARG C 3 118 ? 34.33000 58.05000 47.02600  1.000 93.10000  ?  97   ARG R    NH2 1 
ATOM   5040 N N   . GLU C 3 119 ? 38.40000 52.05600 48.94000  1.000 73.09000  ?  98   GLU R    N   1 
ATOM   5041 C CA  . GLU C 3 119 ? 38.43200 51.38700 47.64000  1.000 72.15000  ?  98   GLU R    CA  1 
ATOM   5042 C C   . GLU C 3 119 ? 37.73100 50.04300 47.72000  1.000 73.36000  ?  98   GLU R    C   1 
ATOM   5043 O O   . GLU C 3 119 ? 36.91600 49.70200 46.85300  1.000 69.64000  ?  98   GLU R    O   1 
ATOM   5044 C CB  . GLU C 3 119 ? 39.86300 51.19300 47.12900  1.000 72.89000  ?  98   GLU R    CB  1 
ATOM   5045 C CG  . GLU C 3 119 ? 40.64600 52.48400 46.82500  1.000 86.47000  ?  98   GLU R    CG  1 
ATOM   5046 C CD  . GLU C 3 119 ? 39.84200 53.54500 46.02800  1.000 102.30000 ?  98   GLU R    CD  1 
ATOM   5047 O OE1 . GLU C 3 119 ? 38.99000 53.18500 45.17000  1.000 101.28000 ?  98   GLU R    OE1 1 
ATOM   5048 O OE2 . GLU C 3 119 ? 40.07400 54.76200 46.27600  1.000 107.77000 ?  98   GLU R    OE2 1 
ATOM   5049 N N   . GLN C 3 120 ? 38.00800 49.29000 48.79100  1.000 72.94000  ?  99   GLN R    N   1 
ATOM   5050 C CA  . GLN C 3 120 ? 37.42400 47.97100 48.97500  1.000 66.88000  ?  99   GLN R    CA  1 
ATOM   5051 C C   . GLN C 3 120 ? 35.92300 48.03700 49.22900  1.000 67.59000  ?  99   GLN R    C   1 
ATOM   5052 O O   . GLN C 3 120 ? 35.18800 47.10100 48.88700  1.000 66.52000  ?  99   GLN R    O   1 
ATOM   5053 C CB  . GLN C 3 120 ? 38.11000 47.28300 50.13400  1.000 65.33000  ?  99   GLN R    CB  1 
ATOM   5054 C CG  . GLN C 3 120 ? 37.57500 45.90600 50.38700  1.000 72.62000  ?  99   GLN R    CG  1 
ATOM   5055 C CD  . GLN C 3 120 ? 38.51800 45.07100 51.20000  1.000 75.64000  ?  99   GLN R    CD  1 
ATOM   5056 O OE1 . GLN C 3 120 ? 39.58700 45.53900 51.60500  1.000 78.08000  ?  99   GLN R    OE1 1 
ATOM   5057 N NE2 . GLN C 3 120 ? 38.13200 43.82500 51.45500  1.000 71.94000  ?  99   GLN R    NE2 1 
ATOM   5058 N N   . ILE C 3 121 ? 35.48300 49.04900 49.96700  1.000 66.59000  ?  100  ILE R    N   1 
ATOM   5059 C CA  . ILE C 3 121 ? 34.03500 49.08500 50.31700  1.000 68.62000  ?  100  ILE R    CA  1 
ATOM   5060 C C   . ILE C 3 121 ? 33.30100 49.34900 49.01000  1.000 68.66000  ?  100  ILE R    C   1 
ATOM   5061 O O   . ILE C 3 121 ? 32.32000 48.62600 48.70900  1.000 67.35000  ?  100  ILE R    O   1 
ATOM   5062 C CB  . ILE C 3 121 ? 33.73800 50.14400 51.39200  1.000 65.39000  ?  100  ILE R    CB  1 
ATOM   5063 C CG1 . ILE C 3 121 ? 34.46100 49.83200 52.70300  1.000 63.43000  ?  100  ILE R    CG1 1 
ATOM   5064 C CG2 . ILE C 3 121 ? 32.24200 50.28900 51.59600  1.000 60.58000  ?  100  ILE R    CG2 1 
ATOM   5065 C CD1 . ILE C 3 121 ? 34.24600 50.86300 53.78000  1.000 64.71000  ?  100  ILE R    CD1 1 
ATOM   5066 N N   . LYS C 3 122 ? 33.80000 50.32200 48.25100  1.000 67.69000  ?  101  LYS R    N   1 
ATOM   5067 C CA  . LYS C 3 122 ? 33.20400 50.58400 46.92100  1.000 71.09000  ?  101  LYS R    CA  1 
ATOM   5068 C C   . LYS C 3 122 ? 33.15700 49.26100 46.16100  1.000 72.68000  ?  101  LYS R    C   1 
ATOM   5069 O O   . LYS C 3 122 ? 32.10300 48.75900 46.03400  1.000 70.01000  ?  101  LYS R    O   1 
ATOM   5070 C CB  . LYS C 3 122 ? 33.98500 51.66700 46.17500  1.000 68.12000  ?  101  LYS R    CB  1 
ATOM   5071 C CG  . LYS C 3 122 ? 33.72700 53.08900 46.65200  1.000 75.41000  ?  101  LYS R    CG  1 
ATOM   5072 C CD  . LYS C 3 122 ? 34.86900 54.03300 46.35900  1.000 85.55000  ?  101  LYS R    CD  1 
ATOM   5073 C CE  . LYS C 3 122 ? 35.27300 54.04700 44.90100  1.000 87.35000  ?  101  LYS R    CE  1 
ATOM   5074 N NZ  . LYS C 3 122 ? 36.48900 54.86400 44.68100  1.000 90.33000  ?  101  LYS R    NZ  1 
ATOM   5075 N N   . ARG C 3 123 ? 34.27400 48.64300 45.81900  1.000 68.07000  ?  102  ARG R    N   1 
ATOM   5076 C CA  . ARG C 3 123 ? 34.18700 47.40800 44.99600  1.000 62.67000  ?  102  ARG R    CA  1 
ATOM   5077 C C   . ARG C 3 123 ? 33.00600 46.54400 45.44600  1.000 67.58000  ?  102  ARG R    C   1 
ATOM   5078 O O   . ARG C 3 123 ? 32.16400 46.24700 44.56500  1.000 71.70000  ?  102  ARG R    O   1 
ATOM   5079 C CB  . ARG C 3 123 ? 35.46400 46.58400 45.16600  1.000 65.32000  ?  102  ARG R    CB  1 
ATOM   5080 C CG  . ARG C 3 123 ? 35.57400 45.39700 44.22300  1.000 63.19000  ?  102  ARG R    CG  1 
ATOM   5081 C CD  . ARG C 3 123 ? 36.80800 45.50400 43.34900  1.000 66.26000  ?  102  ARG R    CD  1 
ATOM   5082 N NE  . ARG C 3 123 ? 38.04600 45.37600 44.10000  1.000 68.31000  ?  102  ARG R    NE  1 
ATOM   5083 C CZ  . ARG C 3 123 ? 39.25800 45.43400 43.56200  1.000 73.89000  ?  102  ARG R    CZ  1 
ATOM   5084 N NH1 . ARG C 3 123 ? 39.40100 45.72600 42.28300  1.000 73.91000  ?  102  ARG R    NH1 1 
ATOM   5085 N NH2 . ARG C 3 123 ? 40.32400 45.20200 44.30600  1.000 80.38000  ?  102  ARG R    NH2 1 
ATOM   5086 N N   . VAL C 3 124 ? 32.92100 46.20000 46.73800  1.000 70.83000  ?  103  VAL R    N   1 
ATOM   5087 C CA  . VAL C 3 124 ? 31.89400 45.23500 47.25300  1.000 69.22000  ?  103  VAL R    CA  1 
ATOM   5088 C C   . VAL C 3 124 ? 30.46000 45.76600 47.14300  1.000 72.42000  ?  103  VAL R    C   1 
ATOM   5089 O O   . VAL C 3 124 ? 29.66300 45.09900 46.47500  1.000 77.89000  ?  103  VAL R    O   1 
ATOM   5090 C CB  . VAL C 3 124 ? 32.21500 44.79600 48.69500  1.000 66.27000  ?  103  VAL R    CB  1 
ATOM   5091 C CG1 . VAL C 3 124 ? 33.61800 44.22300 48.80300  1.000 68.29000  ?  103  VAL R    CG1 1 
ATOM   5092 C CG2 . VAL C 3 124 ? 32.02300 45.91200 49.70500  1.000 71.87000  ?  103  VAL R    CG2 1 
ATOM   5093 N N   . LYS C 3 125 ? 30.12000 46.89200 47.76900  1.000 71.29000  ?  104  LYS R    N   1 
ATOM   5094 C CA  . LYS C 3 125 ? 28.73800 47.40900 47.57400  1.000 72.39000  ?  104  LYS R    CA  1 
ATOM   5095 C C   . LYS C 3 125 ? 28.46800 47.57600 46.07300  1.000 75.88000  ?  104  LYS R    C   1 
ATOM   5096 O O   . LYS C 3 125 ? 27.28600 47.53600 45.67900  1.000 81.74000  ?  104  LYS R    O   1 
ATOM   5097 C CB  . LYS C 3 125 ? 28.56000 48.70000 48.37300  1.000 66.20000  ?  104  LYS R    CB  1 
ATOM   5098 C CG  . LYS C 3 125 ? 28.64500 48.54700 49.88500  1.000 63.23000  ?  104  LYS R    CG  1 
ATOM   5099 C CD  . LYS C 3 125 ? 27.38500 47.99400 50.51500  1.000 61.34000  ?  104  LYS R    CD  1 
ATOM   5100 C CE  . LYS C 3 125 ? 27.20500 46.50500 50.31400  1.000 68.29000  ?  104  LYS R    CE  1 
ATOM   5101 N NZ  . LYS C 3 125 ? 25.92900 46.02700 50.89500  1.000 69.88000  ?  104  LYS R    NZ  1 
ATOM   5102 N N   . ASP C 3 126 ? 29.51200 47.77000 45.27400  1.000 69.37000  ?  105  ASP R    N   1 
ATOM   5103 C CA  . ASP C 3 126 ? 29.41800 47.89100 43.79300  1.000 73.40000  ?  105  ASP R    CA  1 
ATOM   5104 C C   . ASP C 3 126 ? 28.89300 49.27600 43.46500  1.000 77.06000  ?  105  ASP R    C   1 
ATOM   5105 O O   . ASP C 3 126 ? 27.82500 49.33300 42.82700  1.000 82.26000  ?  105  ASP R    O   1 
ATOM   5106 C CB  . ASP C 3 126 ? 28.54300 46.81400 43.15800  1.000 77.27000  ?  105  ASP R    CB  1 
ATOM   5107 C CG  . ASP C 3 126 ? 28.69500 46.74400 41.64800  1.000 94.15000  ?  105  ASP R    CG  1 
ATOM   5108 O OD1 . ASP C 3 126 ? 29.50800 47.51800 41.10500  1.000 88.70000  ?  105  ASP R    OD1 1 
ATOM   5109 O OD2 . ASP C 3 126 ? 27.99700 45.92000 41.02500  1.000 101.23000 ?  105  ASP R    OD2 1 
ATOM   5110 N N   . SER C 3 127 ? 29.67700 50.31000 43.77300  1.000 73.27000  ?  106  SER R    N   1 
ATOM   5111 C CA  . SER C 3 127 ? 29.15300 51.65700 43.64400  1.000 80.19000  ?  106  SER R    CA  1 
ATOM   5112 C C   . SER C 3 127 ? 30.32100 52.59200 43.82500  1.000 84.77000  ?  106  SER R    C   1 
ATOM   5113 O O   . SER C 3 127 ? 31.30100 52.22200 44.46800  1.000 87.06000  ?  106  SER R    O   1 
ATOM   5114 C CB  . SER C 3 127 ? 27.99700 51.91100 44.59900  1.000 82.20000  ?  106  SER R    CB  1 
ATOM   5115 O OG  . SER C 3 127 ? 27.69300 53.28900 44.62000  1.000 89.69000  ?  106  SER R    OG  1 
ATOM   5116 N N   . GLU C 3 128 ? 30.20200 53.82100 43.33300  1.000 88.51000  ?  107  GLU R    N   1 
ATOM   5117 C CA  . GLU C 3 128 ? 31.20500 54.83200 43.62900  1.000 93.68000  ?  107  GLU R    CA  1 
ATOM   5118 C C   . GLU C 3 128 ? 30.69000 55.82000 44.66100  1.000 97.51000  ?  107  GLU R    C   1 
ATOM   5119 O O   . GLU C 3 128 ? 31.45100 56.68900 45.09800  1.000 102.62000 ?  107  GLU R    O   1 
ATOM   5120 C CB  . GLU C 3 128 ? 31.65200 55.56500 42.36500  1.000 95.68000  ?  107  GLU R    CB  1 
ATOM   5121 C CG  . GLU C 3 128 ? 32.08800 54.62700 41.24300  1.000 102.18000 ?  107  GLU R    CG  1 
ATOM   5122 C CD  . GLU C 3 128 ? 33.45100 53.99300 41.54700  1.000 111.11000 ?  107  GLU R    CD  1 
ATOM   5123 O OE1 . GLU C 3 128 ? 34.38600 54.75600 41.92100  1.000 113.54000 ?  107  GLU R    OE1 1 
ATOM   5124 O OE2 . GLU C 3 128 ? 33.58700 52.74400 41.41200  1.000 113.18000 ?  107  GLU R    OE2 1 
ATOM   5125 N N   . ASP C 3 129 ? 29.43700 55.68400 45.08300  1.000 93.59000  ?  108  ASP R    N   1 
ATOM   5126 C CA  . ASP C 3 129 ? 28.81400 56.58200 46.04600  1.000 94.24000  ?  108  ASP R    CA  1 
ATOM   5127 C C   . ASP C 3 129 ? 28.12900 55.75700 47.14500  1.000 94.37000  ?  108  ASP R    C   1 
ATOM   5128 O O   . ASP C 3 129 ? 26.91700 55.78100 47.36100  1.000 98.25000  ?  108  ASP R    O   1 
ATOM   5129 C CB  . ASP C 3 129 ? 27.91100 57.55800 45.28400  1.000 109.23000 ?  108  ASP R    CB  1 
ATOM   5130 C CG  . ASP C 3 129 ? 27.09900 56.87300 44.17100  1.000 122.61000 ?  108  ASP R    CG  1 
ATOM   5131 O OD1 . ASP C 3 129 ? 27.00000 55.61800 44.20600  1.000 120.32000 ?  108  ASP R    OD1 1 
ATOM   5132 O OD2 . ASP C 3 129 ? 26.59100 57.58300 43.25400  1.000 119.07000 ?  108  ASP R    OD2 1 
ATOM   5133 N N   . VAL C 3 130 ? 28.96100 55.00500 47.84700  1.000 88.61000  ?  109  VAL R    N   1 
ATOM   5134 C CA  . VAL C 3 130 ? 28.54200 54.26000 49.03300  1.000 78.47000  ?  109  VAL R    CA  1 
ATOM   5135 C C   . VAL C 3 130 ? 28.54000 55.21500 50.22500  1.000 79.36000  ?  109  VAL R    C   1 
ATOM   5136 O O   . VAL C 3 130 ? 29.49400 56.00300 50.36800  1.000 83.70000  ?  109  VAL R    O   1 
ATOM   5137 C CB  . VAL C 3 130 ? 29.49500 53.09300 49.26100  1.000 77.02000  ?  109  VAL R    CB  1 
ATOM   5138 C CG1 . VAL C 3 130 ? 29.23700 52.41600 50.57800  1.000 71.83000  ?  109  VAL R    CG1 1 
ATOM   5139 C CG2 . VAL C 3 130 ? 29.39300 52.11300 48.10700  1.000 74.75000  ?  109  VAL R    CG2 1 
ATOM   5140 N N   . PRO C 3 131 ? 27.48300 55.19300 51.10700  1.000 73.56000  ?  110  PRO R    N   1 
ATOM   5141 C CA  . PRO C 3 131 ? 27.44200 56.11500 52.25100  1.000 74.36000  ?  110  PRO R    CA  1 
ATOM   5142 C C   . PRO C 3 131 ? 28.54300 55.82800 53.25700  1.000 75.10000  ?  110  PRO R    C   1 
ATOM   5143 O O   . PRO C 3 131 ? 28.53100 54.78100 53.92100  1.000 73.95000  ?  110  PRO R    O   1 
ATOM   5144 C CB  . PRO C 3 131 ? 26.07300 55.84200 52.88500  1.000 67.89000  ?  110  PRO R    CB  1 
ATOM   5145 C CG  . PRO C 3 131 ? 25.29900 55.25400 51.89300  1.000 70.06000  ?  110  PRO R    CG  1 
ATOM   5146 C CD  . PRO C 3 131 ? 26.22300 54.45600 51.00300  1.000 76.25000  ?  110  PRO R    CD  1 
ATOM   5147 N N   . MET C 3 132 ? 29.49700 56.74100 53.39300  1.000 72.98000  ?  111  MET R    N   1 
ATOM   5148 C CA  . MET C 3 132 ? 30.53700 56.54300 54.38200  1.000 73.52000  ?  111  MET R    CA  1 
ATOM   5149 C C   . MET C 3 132 ? 30.96500 57.88700 54.93600  1.000 74.78000  ?  111  MET R    C   1 
ATOM   5150 O O   . MET C 3 132 ? 30.92000 58.90500 54.24300  1.000 79.44000  ?  111  MET R    O   1 
ATOM   5151 C CB  . MET C 3 132 ? 31.76400 55.81400 53.82500  1.000 73.58000  ?  111  MET R    CB  1 
ATOM   5152 C CG  . MET C 3 132 ? 32.38900 56.40700 52.59100  1.000 74.22000  ?  111  MET R    CG  1 
ATOM   5153 S SD  . MET C 3 132 ? 33.75600 55.38000 51.99800  1.000 83.50000  ?  111  MET R    SD  1 
ATOM   5154 C CE  . MET C 3 132 ? 33.04000 53.75600 52.11000  1.000 78.31000  ?  111  MET R    CE  1 
ATOM   5155 N N   . VAL C 3 133 ? 31.38200 57.86700 56.19500  1.000 71.34000  ?  112  VAL R    N   1 
ATOM   5156 C CA  . VAL C 3 133 ? 31.95200 59.01000 56.89000  1.000 70.58000  ?  112  VAL R    CA  1 
ATOM   5157 C C   . VAL C 3 133 ? 33.31300 58.60300 57.44900  1.000 67.22000  ?  112  VAL R    C   1 
ATOM   5158 O O   . VAL C 3 133 ? 33.50800 57.45200 57.84400  1.000 67.92000  ?  112  VAL R    O   1 
ATOM   5159 C CB  . VAL C 3 133 ? 30.98400 59.50400 57.98300  1.000 70.68000  ?  112  VAL R    CB  1 
ATOM   5160 C CG1 . VAL C 3 133 ? 30.57500 58.36400 58.84700  1.000 73.06000  ?  112  VAL R    CG1 1 
ATOM   5161 C CG2 . VAL C 3 133 ? 31.68200 60.50400 58.87600  1.000 75.98000  ?  112  VAL R    CG2 1 
ATOM   5162 N N   . LEU C 3 134 ? 34.26800 59.52600 57.43100  1.000 65.82000  ?  113  LEU R    N   1 
ATOM   5163 C CA  . LEU C 3 134 ? 35.64200 59.26700 57.85100  1.000 64.49000  ?  113  LEU R    CA  1 
ATOM   5164 C C   . LEU C 3 134 ? 35.82000 59.72900 59.28600  1.000 65.65000  ?  113  LEU R    C   1 
ATOM   5165 O O   . LEU C 3 134 ? 35.63900 60.91200 59.58000  1.000 69.25000  ?  113  LEU R    O   1 
ATOM   5166 C CB  . LEU C 3 134 ? 36.63200 60.00100 56.95100  1.000 67.03000  ?  113  LEU R    CB  1 
ATOM   5167 C CG  . LEU C 3 134 ? 38.04100 60.21800 57.49500  1.000 64.13000  ?  113  LEU R    CG  1 
ATOM   5168 C CD1 . LEU C 3 134 ? 38.82300 58.94300 57.44200  1.000 64.72000  ?  113  LEU R    CD1 1 
ATOM   5169 C CD2 . LEU C 3 134 ? 38.75300 61.29400 56.71900  1.000 68.85000  ?  113  LEU R    CD2 1 
ATOM   5170 N N   . VAL C 3 135 ? 36.19800 58.80700 60.16700  1.000 64.03000  ?  114  VAL R    N   1 
ATOM   5171 C CA  . VAL C 3 135 ? 36.25300 59.05300 61.60400  1.000 61.07000  ?  114  VAL R    CA  1 
ATOM   5172 C C   . VAL C 3 135 ? 37.70000 58.98800 62.06200  1.000 62.22000  ?  114  VAL R    C   1 
ATOM   5173 O O   . VAL C 3 135 ? 38.37700 57.97200 61.86700  1.000 60.49000  ?  114  VAL R    O   1 
ATOM   5174 C CB  . VAL C 3 135 ? 35.39200 58.05300 62.38400  1.000 57.50000  ?  114  VAL R    CB  1 
ATOM   5175 C CG1 . VAL C 3 135 ? 35.65100 58.17600 63.84600  1.000 60.80000  ?  114  VAL R    CG1 1 
ATOM   5176 C CG2 . VAL C 3 135 ? 33.96300 58.33000 62.11900  1.000 67.47000  ?  114  VAL R    CG2 1 
ATOM   5177 N N   . GLY C 3 136 ? 38.16400 60.06600 62.68800  1.000 66.70000  ?  115  GLY R    N   1 
ATOM   5178 C CA  . GLY C 3 136 ? 39.50400 60.12700 63.23700  1.000 67.61000  ?  115  GLY R    CA  1 
ATOM   5179 C C   . GLY C 3 136 ? 39.49000 60.10600 64.74700  1.000 69.27000  ?  115  GLY R    C   1 
ATOM   5180 O O   . GLY C 3 136 ? 38.98200 61.02600 65.38500  1.000 71.38000  ?  115  GLY R    O   1 
ATOM   5181 N N   . ASN C 3 137 ? 40.05900 59.06400 65.32900  1.000 70.80000  ?  116  ASN R    N   1 
ATOM   5182 C CA  . ASN C 3 137 ? 39.89600 58.77800 66.74200  1.000 69.95000  ?  116  ASN R    CA  1 
ATOM   5183 C C   . ASN C 3 137 ? 41.10200 59.21800 67.54000  1.000 70.87000  ?  116  ASN R    C   1 
ATOM   5184 O O   . ASN C 3 137 ? 42.23900 59.10300 67.08300  1.000 72.94000  ?  116  ASN R    O   1 
ATOM   5185 C CB  . ASN C 3 137 ? 39.68300 57.29300 66.96200  1.000 74.58000  ?  116  ASN R    CB  1 
ATOM   5186 C CG  . ASN C 3 137 ? 38.89900 57.02700 68.18200  1.000 74.08000  ?  116  ASN R    CG  1 
ATOM   5187 O OD1 . ASN C 3 137 ? 38.04700 57.82000 68.54300  1.000 75.51000  ?  116  ASN R    OD1 1 
ATOM   5188 N ND2 . ASN C 3 137 ? 39.18200 55.91800 68.84700  1.000 78.60000  ?  116  ASN R    ND2 1 
ATOM   5189 N N   . LYS C 3 138 ? 40.84800 59.68600 68.75200  1.000 80.99000  ?  117  LYS R    N   1 
ATOM   5190 C CA  . LYS C 3 138 ? 41.91300 60.10100 69.65900  1.000 87.97000  ?  117  LYS R    CA  1 
ATOM   5191 C C   . LYS C 3 138 ? 42.10500 59.00500 70.71300  1.000 92.66000  ?  117  LYS R    C   1 
ATOM   5192 O O   . LYS C 3 138 ? 41.39300 58.94500 71.71200  1.000 88.07000  ?  117  LYS R    O   1 
ATOM   5193 C CB  . LYS C 3 138 ? 41.60100 61.46000 70.27900  1.000 77.47000  ?  117  LYS R    CB  1 
ATOM   5194 C CG  . LYS C 3 138 ? 42.80100 62.01700 70.96800  1.000 88.83000  ?  117  LYS R    CG  1 
ATOM   5195 C CD  . LYS C 3 138 ? 42.47300 63.14200 71.90000  1.000 87.00000  ?  117  LYS R    CD  1 
ATOM   5196 C CE  . LYS C 3 138 ? 43.73100 63.56300 72.61800  1.000 92.60000  ?  117  LYS R    CE  1 
ATOM   5197 N NZ  . LYS C 3 138 ? 43.42300 64.61500 73.60500  1.000 103.09000 ?  117  LYS R    NZ  1 
ATOM   5198 N N   . CYS C 3 139 ? 43.02800 58.08300 70.43100  1.000 101.10000 ?  118  CYS R    N   1 
ATOM   5199 C CA  . CYS C 3 139 ? 43.70800 57.29700 71.45900  1.000 106.26000 ?  118  CYS R    CA  1 
ATOM   5200 C C   . CYS C 3 139 ? 44.79800 58.20300 72.00100  1.000 113.66000 ?  118  CYS R    C   1 
ATOM   5201 O O   . CYS C 3 139 ? 45.77700 58.49900 71.30800  1.000 112.66000 ?  118  CYS R    O   1 
ATOM   5202 C CB  . CYS C 3 139 ? 44.30000 56.01300 70.88700  1.000 111.67000 ?  118  CYS R    CB  1 
ATOM   5203 S SG  . CYS C 3 139 ? 43.14600 54.62600 70.71000  1.000 123.93000 ?  118  CYS R    SG  1 
ATOM   5204 N N   . ASP C 3 140 ? 44.62000 58.65500 73.24100  1.000 124.04000 ?  119  ASP R    N   1 
ATOM   5205 C CA  . ASP C 3 140 ? 45.38100 59.76300 73.81200  1.000 127.02000 ?  119  ASP R    CA  1 
ATOM   5206 C C   . ASP C 3 140 ? 46.87100 59.41900 73.97800  1.000 127.36000 ?  119  ASP R    C   1 
ATOM   5207 O O   . ASP C 3 140 ? 47.68200 60.26900 74.36700  1.000 124.57000 ?  119  ASP R    O   1 
ATOM   5208 C CB  . ASP C 3 140 ? 44.71500 60.15000 75.15400  1.000 129.32000 ?  119  ASP R    CB  1 
ATOM   5209 C CG  . ASP C 3 140 ? 45.32500 61.39500 75.79200  1.000 140.96000 ?  119  ASP R    CG  1 
ATOM   5210 O OD1 . ASP C 3 140 ? 45.93400 62.20400 75.04700  1.000 146.03000 ?  119  ASP R    OD1 1 
ATOM   5211 O OD2 . ASP C 3 140 ? 45.18200 61.55900 77.03000  1.000 131.72000 ?  119  ASP R    OD2 1 
ATOM   5212 N N   . LEU C 3 141 ? 47.24000 58.18500 73.62600  1.000 127.27000 ?  120  LEU R    N   1 
ATOM   5213 C CA  . LEU C 3 141 ? 48.46500 57.50900 74.02000  1.000 122.83000 ?  120  LEU R    CA  1 
ATOM   5214 C C   . LEU C 3 141 ? 49.76600 58.22700 73.60600  1.000 116.33000 ?  120  LEU R    C   1 
ATOM   5215 O O   . LEU C 3 141 ? 50.50000 58.66100 74.50300  1.000 108.55000 ?  120  LEU R    O   1 
ATOM   5216 C CB  . LEU C 3 141 ? 48.41600 56.07000 73.47600  1.000 127.26000 ?  120  LEU R    CB  1 
ATOM   5217 C CG  . LEU C 3 141 ? 47.04300 55.35400 73.50300  1.000 130.02000 ?  120  LEU R    CG  1 
ATOM   5218 C CD1 . LEU C 3 141 ? 47.11800 54.00300 72.76200  1.000 126.44000 ?  120  LEU R    CD1 1 
ATOM   5219 C CD2 . LEU C 3 141 ? 46.46100 55.20600 74.92700  1.000 124.13000 ?  120  LEU R    CD2 1 
ATOM   5220 N N   . PRO C 3 142 ? 50.13400 58.40200 72.26300  1.000 120.00000 ?  121  PRO R    N   1 
ATOM   5221 C CA  . PRO C 3 142 ? 51.26800 59.29900 71.95000  1.000 113.91000 ?  121  PRO R    CA  1 
ATOM   5222 C C   . PRO C 3 142 ? 50.68800 60.61600 71.46700  1.000 104.99000 ?  121  PRO R    C   1 
ATOM   5223 O O   . PRO C 3 142 ? 49.47500 60.83000 71.56700  1.000 108.19000 ?  121  PRO R    O   1 
ATOM   5224 C CB  . PRO C 3 142 ? 52.04700 58.60100 70.82400  1.000 110.60000 ?  121  PRO R    CB  1 
ATOM   5225 C CG  . PRO C 3 142 ? 51.30000 57.29800 70.52400  1.000 114.22000 ?  121  PRO R    CG  1 
ATOM   5226 C CD  . PRO C 3 142 ? 49.92300 57.48100 71.12200  1.000 117.65000 ?  121  PRO R    CD  1 
ATOM   5227 N N   . SER C 3 143 ? 51.50600 61.50000 70.92300  1.000 92.19000  ?  122  SER R    N   1 
ATOM   5228 C CA  . SER C 3 143 ? 50.93300 62.76500 70.50700  1.000 97.35000  ?  122  SER R    CA  1 
ATOM   5229 C C   . SER C 3 143 ? 50.38000 62.65400 69.08900  1.000 98.71000  ?  122  SER R    C   1 
ATOM   5230 O O   . SER C 3 143 ? 50.86500 61.86100 68.27400  1.000 96.16000  ?  122  SER R    O   1 
ATOM   5231 C CB  . SER C 3 143 ? 51.95500 63.89800 70.59000  1.000 105.20000 ?  122  SER R    CB  1 
ATOM   5232 O OG  . SER C 3 143 ? 51.36800 65.11400 70.13000  1.000 107.57000 ?  122  SER R    OG  1 
ATOM   5233 N N   . ARG C 3 144 ? 49.33400 63.44500 68.81900  1.000 93.32000  ?  123  ARG R    N   1 
ATOM   5234 C CA  . ARG C 3 144 ? 48.73100 63.51900 67.49300  1.000 82.74000  ?  123  ARG R    CA  1 
ATOM   5235 C C   . ARG C 3 144 ? 49.79500 63.68300 66.42700  1.000 83.83000  ?  123  ARG R    C   1 
ATOM   5236 O O   . ARG C 3 144 ? 50.71200 64.48900 66.58900  1.000 92.43000  ?  123  ARG R    O   1 
ATOM   5237 C CB  . ARG C 3 144 ? 47.77900 64.70600 67.41700  1.000 88.21000  ?  123  ARG R    CB  1 
ATOM   5238 C CG  . ARG C 3 144 ? 47.63700 65.24300 66.00000  1.000 80.73000  ?  123  ARG R    CG  1 
ATOM   5239 C CD  . ARG C 3 144 ? 46.73200 66.43000 65.92700  1.000 80.02000  ?  123  ARG R    CD  1 
ATOM   5240 N NE  . ARG C 3 144 ? 45.39800 66.09500 66.39600  1.000 82.14000  ?  123  ARG R    NE  1 
ATOM   5241 C CZ  . ARG C 3 144 ? 44.29300 66.13800 65.65900  1.000 91.81000  ?  123  ARG R    CZ  1 
ATOM   5242 N NH1 . ARG C 3 144 ? 44.33100 66.37600 64.35100  1.000 92.72000  ?  123  ARG R    NH1 1 
ATOM   5243 N NH2 . ARG C 3 144 ? 43.11400 65.92000 66.24500  1.000 91.54000  ?  123  ARG R    NH2 1 
ATOM   5244 N N   . THR C 3 145 ? 49.66400 62.91900 65.32400  1.000 83.81000  ?  124  THR R    N   1 
ATOM   5245 C CA  . THR C 3 145 ? 50.55200 63.03800 64.16800  1.000 76.59000  ?  124  THR R    CA  1 
ATOM   5246 C C   . THR C 3 145 ? 49.79400 63.07700 62.84600  1.000 75.43000  ?  124  THR R    C   1 
ATOM   5247 O O   . THR C 3 145 ? 50.37400 62.73900 61.81100  1.000 80.97000  ?  124  THR R    O   1 
ATOM   5248 C CB  . THR C 3 145 ? 51.59000 61.90100 64.12200  1.000 75.83000  ?  124  THR R    CB  1 
ATOM   5249 O OG1 . THR C 3 145 ? 50.97200 60.68100 63.71100  1.000 74.54000  ?  124  THR R    OG1 1 
ATOM   5250 C CG2 . THR C 3 145 ? 52.26300 61.67500 65.48100  1.000 84.89000  ?  124  THR R    CG2 1 
ATOM   5251 N N   . VAL C 3 146 ? 48.51800 63.47500 62.84500  1.000 79.40000  ?  125  VAL R    N   1 
ATOM   5252 C CA  . VAL C 3 146 ? 47.71900 63.60700 61.61800  1.000 79.58000  ?  125  VAL R    CA  1 
ATOM   5253 C C   . VAL C 3 146 ? 46.95700 64.91900 61.73600  1.000 81.05000  ?  125  VAL R    C   1 
ATOM   5254 O O   . VAL C 3 146 ? 46.04800 65.03200 62.56100  1.000 84.95000  ?  125  VAL R    O   1 
ATOM   5255 C CB  . VAL C 3 146 ? 46.73100 62.44400 61.41000  1.000 71.59000  ?  125  VAL R    CB  1 
ATOM   5256 C CG1 . VAL C 3 146 ? 45.77000 62.75800 60.27400  1.000 67.88000  ?  125  VAL R    CG1 1 
ATOM   5257 C CG2 . VAL C 3 146 ? 47.44000 61.11100 61.19300  1.000 66.59000  ?  125  VAL R    CG2 1 
ATOM   5258 N N   . ASP C 3 147 ? 47.31800 65.90900 60.93200  1.000 86.84000  ?  126  ASP R    N   1 
ATOM   5259 C CA  . ASP C 3 147 ? 46.63500 67.19400 61.05100  1.000 93.44000  ?  126  ASP R    CA  1 
ATOM   5260 C C   . ASP C 3 147 ? 45.20600 67.12600 60.55800  1.000 89.80000  ?  126  ASP R    C   1 
ATOM   5261 O O   . ASP C 3 147 ? 44.94000 66.73300 59.41600  1.000 86.77000  ?  126  ASP R    O   1 
ATOM   5262 C CB  . ASP C 3 147 ? 47.38100 68.31400 60.33100  1.000 98.50000  ?  126  ASP R    CB  1 
ATOM   5263 C CG  . ASP C 3 147 ? 48.43200 68.95300 61.22200  1.000 115.88000 ?  126  ASP R    CG  1 
ATOM   5264 O OD1 . ASP C 3 147 ? 48.55400 68.51500 62.39500  1.000 106.89000 ?  126  ASP R    OD1 1 
ATOM   5265 O OD2 . ASP C 3 147 ? 49.09500 69.92000 60.76600  1.000 131.23000 ?  126  ASP R    OD2 1 
ATOM   5266 N N   . THR C 3 148 ? 44.29400 67.55000 61.43600  1.000 88.44000  ?  127  THR R    N   1 
ATOM   5267 C CA  . THR C 3 148 ? 42.89000 67.67700 61.06900  1.000 90.00000  ?  127  THR R    CA  1 
ATOM   5268 C C   . THR C 3 148 ? 42.70400 68.33700 59.70200  1.000 84.50000  ?  127  THR R    C   1 
ATOM   5269 O O   . THR C 3 148 ? 41.72800 68.04000 59.00000  1.000 79.42000  ?  127  THR R    O   1 
ATOM   5270 C CB  . THR C 3 148 ? 42.14300 68.42200 62.18900  1.000 87.74000  ?  127  THR R    CB  1 
ATOM   5271 O OG1 . THR C 3 148 ? 40.75400 68.55300 61.85300  1.000 89.54000  ?  127  THR R    OG1 1 
ATOM   5272 C CG2 . THR C 3 148 ? 42.75900 69.78200 62.50300  1.000 88.98000  ?  127  THR R    CG2 1 
ATOM   5273 N N   . LYS C 3 149 ? 43.63100 69.21100 59.29900  1.000 83.01000  ?  128  LYS R    N   1 
ATOM   5274 C CA  . LYS C 3 149 ? 43.62900 69.71200 57.93100  1.000 84.99000  ?  128  LYS R    CA  1 
ATOM   5275 C C   . LYS C 3 149 ? 43.64300 68.56800 56.92100  1.000 85.90000  ?  128  LYS R    C   1 
ATOM   5276 O O   . LYS C 3 149 ? 42.72100 68.41700 56.11200  1.000 84.21000  ?  128  LYS R    O   1 
ATOM   5277 C CB  . LYS C 3 149 ? 44.83100 70.62100 57.69000  1.000 93.98000  ?  128  LYS R    CB  1 
ATOM   5278 C CG  . LYS C 3 149 ? 44.95900 71.01900 56.20700  1.000 97.72000  ?  128  LYS R    CG  1 
ATOM   5279 C CD  . LYS C 3 149 ? 46.09300 72.00800 55.93600  1.000 102.04000 ?  128  LYS R    CD  1 
ATOM   5280 C CE  . LYS C 3 149 ? 46.08700 72.40000 54.47200  1.000 96.05000  ?  128  LYS R    CE  1 
ATOM   5281 N NZ  . LYS C 3 149 ? 44.68900 72.85100 54.16800  1.000 87.60000  ?  128  LYS R    NZ  1 
ATOM   5282 N N   . GLN C 3 150 ? 44.70600 67.76400 56.95200  1.000 84.57000  ?  129  GLN R    N   1 
ATOM   5283 C CA  . GLN C 3 150 ? 44.82500 66.61800 56.06000  1.000 82.60000  ?  129  GLN R    CA  1 
ATOM   5284 C C   . GLN C 3 150 ? 43.54600 65.80200 56.00700  1.000 81.71000  ?  129  GLN R    C   1 
ATOM   5285 O O   . GLN C 3 150 ? 43.01300 65.52800 54.92600  1.000 78.84000  ?  129  GLN R    O   1 
ATOM   5286 C CB  . GLN C 3 150 ? 45.98800 65.74800 56.51500  1.000 83.46000  ?  129  GLN R    CB  1 
ATOM   5287 C CG  . GLN C 3 150 ? 47.29700 66.44200 56.34200  1.000 92.57000  ?  129  GLN R    CG  1 
ATOM   5288 C CD  . GLN C 3 150 ? 48.44000 65.64500 56.88100  1.000 97.27000  ?  129  GLN R    CD  1 
ATOM   5289 O OE1 . GLN C 3 150 ? 48.26600 64.83400 57.78700  1.000 99.37000  ?  129  GLN R    OE1 1 
ATOM   5290 N NE2 . GLN C 3 150 ? 49.61700 65.83100 56.29700  1.000 107.36000 ?  129  GLN R    NE2 1 
ATOM   5291 N N   . ALA C 3 151 ? 43.03000 65.41200 57.17400  1.000 85.08000  ?  130  ALA R    N   1 
ATOM   5292 C CA  . ALA C 3 151 ? 41.84600 64.55900 57.20400  1.000 83.19000  ?  130  ALA R    CA  1 
ATOM   5293 C C   . ALA C 3 151 ? 40.66700 65.20900 56.48200  1.000 83.34000  ?  130  ALA R    C   1 
ATOM   5294 O O   . ALA C 3 151 ? 40.01000 64.56800 55.65200  1.000 81.75000  ?  130  ALA R    O   1 
ATOM   5295 C CB  . ALA C 3 151 ? 41.49200 64.21600 58.64300  1.000 74.84000  ?  130  ALA R    CB  1 
ATOM   5296 N N   . GLN C 3 152 ? 40.39200 66.48800 56.76400  1.000 82.44000  ?  131  GLN R    N   1 
ATOM   5297 C CA  . GLN C 3 152 ? 39.32600 67.17900 56.04000  1.000 81.64000  ?  131  GLN R    CA  1 
ATOM   5298 C C   . GLN C 3 152 ? 39.61100 67.25700 54.55200  1.000 84.12000  ?  131  GLN R    C   1 
ATOM   5299 O O   . GLN C 3 152 ? 38.71800 67.02000 53.72900  1.000 84.74000  ?  131  GLN R    O   1 
ATOM   5300 C CB  . GLN C 3 152 ? 39.13100 68.58000 56.57800  1.000 82.97000  ?  131  GLN R    CB  1 
ATOM   5301 C CG  . GLN C 3 152 ? 38.42600 68.65000 57.86900  1.000 85.00000  ?  131  GLN R    CG  1 
ATOM   5302 C CD  . GLN C 3 152 ? 38.85000 69.85500 58.61200  1.000 86.58000  ?  131  GLN R    CD  1 
ATOM   5303 O OE1 . GLN C 3 152 ? 39.82800 70.50200 58.22700  1.000 86.24000  ?  131  GLN R    OE1 1 
ATOM   5304 N NE2 . GLN C 3 152 ? 38.11400 70.19800 59.67100  1.000 88.08000  ?  131  GLN R    NE2 1 
ATOM   5305 N N   . ASP C 3 153 ? 40.83900 67.64100 54.19200  1.000 80.71000  ?  132  ASP R    N   1 
ATOM   5306 C CA  . ASP C 3 153 ? 41.23500 67.68400 52.79000  1.000 81.77000  ?  132  ASP R    CA  1 
ATOM   5307 C C   . ASP C 3 153 ? 41.00500 66.34200 52.11400  1.000 84.67000  ?  132  ASP R    C   1 
ATOM   5308 O O   . ASP C 3 153 ? 40.44200 66.27000 51.01100  1.000 88.43000  ?  132  ASP R    O   1 
ATOM   5309 C CB  . ASP C 3 153 ? 42.70000 68.08400 52.68700  1.000 87.78000  ?  132  ASP R    CB  1 
ATOM   5310 C CG  . ASP C 3 153 ? 42.89300 69.58000 52.68300  1.000 95.52000  ?  132  ASP R    CG  1 
ATOM   5311 O OD1 . ASP C 3 153 ? 41.91600 70.32200 52.99200  1.000 95.00000  ?  132  ASP R    OD1 1 
ATOM   5312 O OD2 . ASP C 3 153 ? 44.04000 69.99400 52.38700  1.000 93.51000  ?  132  ASP R    OD2 1 
ATOM   5313 N N   . LEU C 3 154 ? 41.44800 65.26600 52.76200  1.000 81.39000  ?  133  LEU R    N   1 
ATOM   5314 C CA  . LEU C 3 154 ? 41.12900 63.92900 52.28300  1.000 78.04000  ?  133  LEU R    CA  1 
ATOM   5315 C C   . LEU C 3 154 ? 39.62500 63.72100 52.20600  1.000 77.90000  ?  133  LEU R    C   1 
ATOM   5316 O O   . LEU C 3 154 ? 39.10200 63.23700 51.19900  1.000 77.95000  ?  133  LEU R    O   1 
ATOM   5317 C CB  . LEU C 3 154 ? 41.75800 62.88800 53.19500  1.000 73.43000  ?  133  LEU R    CB  1 
ATOM   5318 C CG  . LEU C 3 154 ? 41.63800 61.46100 52.69900  1.000 67.14000  ?  133  LEU R    CG  1 
ATOM   5319 C CD1 . LEU C 3 154 ? 42.37100 61.28700 51.40800  1.000 66.83000  ?  133  LEU R    CD1 1 
ATOM   5320 C CD2 . LEU C 3 154 ? 42.23200 60.58300 53.75400  1.000 73.54000  ?  133  LEU R    CD2 1 
ATOM   5321 N N   . ALA C 3 155 ? 38.90600 64.07800 53.26400  1.000 79.44000  ?  134  ALA R    N   1 
ATOM   5322 C CA  . ALA C 3 155 ? 37.47700 63.80900 53.26100  1.000 80.99000  ?  134  ALA R    CA  1 
ATOM   5323 C C   . ALA C 3 155 ? 36.75800 64.63500 52.21200  1.000 79.97000  ?  134  ALA R    C   1 
ATOM   5324 O O   . ALA C 3 155 ? 35.72400 64.18800 51.70000  1.000 77.73000  ?  134  ALA R    O   1 
ATOM   5325 C CB  . ALA C 3 155 ? 36.87200 64.05400 54.64300  1.000 80.25000  ?  134  ALA R    CB  1 
ATOM   5326 N N   . ARG C 3 156 ? 37.28800 65.82400 51.87000  1.000 79.18000  ?  135  ARG R    N   1 
ATOM   5327 C CA  . ARG C 3 156 ? 36.64300 66.65200 50.84800  1.000 82.24000  ?  135  ARG R    CA  1 
ATOM   5328 C C   . ARG C 3 156 ? 36.69300 65.97000 49.48400  1.000 87.83000  ?  135  ARG R    C   1 
ATOM   5329 O O   . ARG C 3 156 ? 35.67300 65.87200 48.78100  1.000 83.13000  ?  135  ARG R    O   1 
ATOM   5330 C CB  . ARG C 3 156 ? 37.28400 68.03900 50.76000  1.000 76.50000  ?  135  ARG R    CB  1 
ATOM   5331 C CG  . ARG C 3 156 ? 36.55500 68.92500 49.72700  1.000 85.31000  ?  135  ARG R    CG  1 
ATOM   5332 C CD  . ARG C 3 156 ? 36.81900 70.41100 49.88100  1.000 82.13000  ?  135  ARG R    CD  1 
ATOM   5333 N NE  . ARG C 3 156 ? 35.93100 70.98200 50.88000  1.000 83.70000  ?  135  ARG R    NE  1 
ATOM   5334 C CZ  . ARG C 3 156 ? 36.33200 71.34200 52.09600  1.000 91.58000  ?  135  ARG R    CZ  1 
ATOM   5335 N NH1 . ARG C 3 156 ? 37.59600 71.19900 52.48500  1.000 89.40000  ?  135  ARG R    NH1 1 
ATOM   5336 N NH2 . ARG C 3 156 ? 35.44200 71.83000 52.95400  1.000 89.41000  ?  135  ARG R    NH2 1 
ATOM   5337 N N   . SER C 3 157 ? 37.88700 65.49400 49.10000  1.000 82.55000  ?  136  SER R    N   1 
ATOM   5338 C CA  . SER C 3 157 ? 38.06000 64.72500 47.87600  1.000 77.68000  ?  136  SER R    CA  1 
ATOM   5339 C C   . SER C 3 157 ? 37.08300 63.55700 47.78100  1.000 78.23000  ?  136  SER R    C   1 
ATOM   5340 O O   . SER C 3 157 ? 36.41700 63.37800 46.76000  1.000 86.19000  ?  136  SER R    O   1 
ATOM   5341 C CB  . SER C 3 157 ? 39.48900 64.21900 47.80500  1.000 80.46000  ?  136  SER R    CB  1 
ATOM   5342 O OG  . SER C 3 157 ? 39.86500 63.67800 49.04300  1.000 78.55000  ?  136  SER R    OG  1 
ATOM   5343 N N   . TYR C 3 158 ? 36.99500 62.72900 48.81900  1.000 78.10000  ?  137  TYR R    N   1 
ATOM   5344 C CA  . TYR C 3 158 ? 36.05900 61.61300 48.71100  1.000 80.51000  ?  137  TYR R    CA  1 
ATOM   5345 C C   . TYR C 3 158 ? 34.59900 62.07300 48.75500  1.000 81.48000  ?  137  TYR R    C   1 
ATOM   5346 O O   . TYR C 3 158 ? 33.70600 61.27000 48.44200  1.000 80.22000  ?  137  TYR R    O   1 
ATOM   5347 C CB  . TYR C 3 158 ? 36.33600 60.56600 49.81300  1.000 82.41000  ?  137  TYR R    CB  1 
ATOM   5348 C CG  . TYR C 3 158 ? 37.70900 59.91800 49.70700  1.000 80.48000  ?  137  TYR R    CG  1 
ATOM   5349 C CD1 . TYR C 3 158 ? 38.31900 59.77800 48.47400  1.000 87.30000  ?  137  TYR R    CD1 1 
ATOM   5350 C CD2 . TYR C 3 158 ? 38.39600 59.44800 50.84000  1.000 76.14000  ?  137  TYR R    CD2 1 
ATOM   5351 C CE1 . TYR C 3 158 ? 39.57500 59.20600 48.34900  1.000 92.90000  ?  137  TYR R    CE1 1 
ATOM   5352 C CE2 . TYR C 3 158 ? 39.66700 58.86000 50.73600  1.000 72.97000  ?  137  TYR R    CE2 1 
ATOM   5353 C CZ  . TYR C 3 158 ? 40.24900 58.74800 49.46700  1.000 89.47000  ?  137  TYR R    CZ  1 
ATOM   5354 O OH  . TYR C 3 158 ? 41.49500 58.19900 49.23900  1.000 89.07000  ?  137  TYR R    OH  1 
ATOM   5355 N N   . GLY C 3 159 ? 34.34000 63.33400 49.10500  1.000 77.28000  ?  138  GLY R    N   1 
ATOM   5356 C CA  . GLY C 3 159 ? 32.98200 63.85900 49.14200  1.000 76.77000  ?  138  GLY R    CA  1 
ATOM   5357 C C   . GLY C 3 159 ? 32.13300 63.34700 50.29000  1.000 81.00000  ?  138  GLY R    C   1 
ATOM   5358 O O   . GLY C 3 159 ? 30.92800 63.10800 50.10900  1.000 78.67000  ?  138  GLY R    O   1 
ATOM   5359 N N   . ILE C 3 160 ? 32.73100 63.20400 51.47400  1.000 79.93000  ?  139  ILE R    N   1 
ATOM   5360 C CA  . ILE C 3 160 ? 32.12900 62.56600 52.64600  1.000 73.55000  ?  139  ILE R    CA  1 
ATOM   5361 C C   . ILE C 3 160 ? 32.42900 63.40100 53.89000  1.000 72.57000  ?  139  ILE R    C   1 
ATOM   5362 O O   . ILE C 3 160 ? 33.39500 64.17100 53.91700  1.000 72.46000  ?  139  ILE R    O   1 
ATOM   5363 C CB  . ILE C 3 160 ? 32.66400 61.13400 52.83600  1.000 72.72000  ?  139  ILE R    CB  1 
ATOM   5364 C CG1 . ILE C 3 160 ? 34.17800 61.17400 53.02100  1.000 75.83000  ?  139  ILE R    CG1 1 
ATOM   5365 C CG2 . ILE C 3 160 ? 32.29500 60.25600 51.67900  1.000 76.47000  ?  139  ILE R    CG2 1 
ATOM   5366 C CD1 . ILE C 3 160 ? 34.78900 59.82900 53.19300  1.000 73.40000  ?  139  ILE R    CD1 1 
ATOM   5367 N N   . PRO C 3 161 ? 31.61200 63.24700 54.94200  1.000 74.35000  ?  140  PRO R    N   1 
ATOM   5368 C CA  . PRO C 3 161 ? 31.88000 63.96100 56.20400  1.000 69.74000  ?  140  PRO R    CA  1 
ATOM   5369 C C   . PRO C 3 161 ? 33.11000 63.43500 56.90800  1.000 70.05000  ?  140  PRO R    C   1 
ATOM   5370 O O   . PRO C 3 161 ? 33.49300 62.27900 56.75200  1.000 73.77000  ?  140  PRO R    O   1 
ATOM   5371 C CB  . PRO C 3 161 ? 30.63200 63.69400 57.05400  1.000 63.63000  ?  140  PRO R    CB  1 
ATOM   5372 C CG  . PRO C 3 161 ? 29.62900 63.13600 56.14800  1.000 72.71000  ?  140  PRO R    CG  1 
ATOM   5373 C CD  . PRO C 3 161 ? 30.34800 62.49700 55.00700  1.000 78.42000  ?  140  PRO R    CD  1 
ATOM   5374 N N   . PHE C 3 162 ? 33.71100 64.30300 57.72100  1.000 71.31000  ?  141  PHE R    N   1 
ATOM   5375 C CA  . PHE C 3 162 ? 34.84300 63.96200 58.58100  1.000 68.54000  ?  141  PHE R    CA  1 
ATOM   5376 C C   . PHE C 3 162 ? 34.52300 64.35200 60.01700  1.000 72.77000  ?  141  PHE R    C   1 
ATOM   5377 O O   . PHE C 3 162 ? 34.14300 65.49700 60.28100  1.000 80.85000  ?  141  PHE R    O   1 
ATOM   5378 C CB  . PHE C 3 162 ? 36.10400 64.68900 58.14500  1.000 68.18000  ?  141  PHE R    CB  1 
ATOM   5379 C CG  . PHE C 3 162 ? 37.20500 64.65200 59.16400  1.000 69.93000  ?  141  PHE R    CG  1 
ATOM   5380 C CD1 . PHE C 3 162 ? 37.76000 63.45400 59.56200  1.000 71.28000  ?  141  PHE R    CD1 1 
ATOM   5381 C CD2 . PHE C 3 162 ? 37.65900 65.81400 59.75200  1.000 72.44000  ?  141  PHE R    CD2 1 
ATOM   5382 C CE1 . PHE C 3 162 ? 38.77900 63.41900 60.49400  1.000 68.26000  ?  141  PHE R    CE1 1 
ATOM   5383 C CE2 . PHE C 3 162 ? 38.68100 65.78900 60.69000  1.000 73.58000  ?  141  PHE R    CE2 1 
ATOM   5384 C CZ  . PHE C 3 162 ? 39.23000 64.58800 61.06500  1.000 72.73000  ?  141  PHE R    CZ  1 
ATOM   5385 N N   . ILE C 3 163 ? 34.69800 63.42300 60.94800  1.000 72.80000  ?  142  ILE R    N   1 
ATOM   5386 C CA  . ILE C 3 163 ? 34.35700 63.66100 62.34800  1.000 74.41000  ?  142  ILE R    CA  1 
ATOM   5387 C C   . ILE C 3 163 ? 35.47900 63.12700 63.23100  1.000 75.44000  ?  142  ILE R    C   1 
ATOM   5388 O O   . ILE C 3 163 ? 35.88200 61.96900 63.08400  1.000 71.84000  ?  142  ILE R    O   1 
ATOM   5389 C CB  . ILE C 3 163 ? 33.02400 62.98700 62.69800  1.000 74.87000  ?  142  ILE R    CB  1 
ATOM   5390 C CG1 . ILE C 3 163 ? 31.90600 63.66700 61.91100  1.000 79.04000  ?  142  ILE R    CG1 1 
ATOM   5391 C CG2 . ILE C 3 163 ? 32.78000 63.03000 64.19500  1.000 75.14000  ?  142  ILE R    CG2 1 
ATOM   5392 C CD1 . ILE C 3 163 ? 30.59600 62.94300 61.95700  1.000 81.06000  ?  142  ILE R    CD1 1 
ATOM   5393 N N   . GLU C 3 164 ? 35.98700 63.96700 64.14500  1.000 76.61000  ?  143  GLU R    N   1 
ATOM   5394 C CA  . GLU C 3 164 ? 37.07800 63.60500 65.05200  1.000 76.15000  ?  143  GLU R    CA  1 
ATOM   5395 C C   . GLU C 3 164 ? 36.47500 63.22400 66.40000  1.000 75.47000  ?  143  GLU R    C   1 
ATOM   5396 O O   . GLU C 3 164 ? 35.73200 64.01400 66.97600  1.000 79.49000  ?  143  GLU R    O   1 
ATOM   5397 C CB  . GLU C 3 164 ? 38.05400 64.77100 65.21500  1.000 79.14000  ?  143  GLU R    CB  1 
ATOM   5398 C CG  . GLU C 3 164 ? 39.39800 64.59200 64.52500  1.000 84.14000  ?  143  GLU R    CG  1 
ATOM   5399 C CD  . GLU C 3 164 ? 40.40000 65.73600 64.79000  1.000 96.28000  ?  143  GLU R    CD  1 
ATOM   5400 O OE1 . GLU C 3 164 ? 40.44000 66.28000 65.93600  1.000 94.44000  ?  143  GLU R    OE1 1 
ATOM   5401 O OE2 . GLU C 3 164 ? 41.15100 66.07700 63.83200  1.000 90.81000  ?  143  GLU R    OE2 1 
ATOM   5402 N N   . THR C 3 165 ? 36.78300 62.02400 66.89500  1.000 71.89000  ?  144  THR R    N   1 
ATOM   5403 C CA  . THR C 3 165 ? 36.15000 61.48000 68.09400  1.000 74.10000  ?  144  THR R    CA  1 
ATOM   5404 C C   . THR C 3 165 ? 37.18000 61.19800 69.18200  1.000 69.33000  ?  144  THR R    C   1 
ATOM   5405 O O   . THR C 3 165 ? 38.37500 61.11200 68.92400  1.000 77.81000  ?  144  THR R    O   1 
ATOM   5406 C CB  . THR C 3 165 ? 35.34200 60.19900 67.77300  1.000 73.69000  ?  144  THR R    CB  1 
ATOM   5407 O OG1 . THR C 3 165 ? 36.21400 59.11500 67.42400  1.000 71.97000  ?  144  THR R    OG1 1 
ATOM   5408 C CG2 . THR C 3 165 ? 34.42400 60.44700 66.61900  1.000 73.36000  ?  144  THR R    CG2 1 
ATOM   5409 N N   . SER C 3 166 ? 36.71800 61.07500 70.41500  1.000 62.76000  ?  145  SER R    N   1 
ATOM   5410 C CA  . SER C 3 166 ? 37.60400 60.74000 71.52400  1.000 75.21000  ?  145  SER R    CA  1 
ATOM   5411 C C   . SER C 3 166 ? 36.97800 59.60500 72.32600  1.000 83.28000  ?  145  SER R    C   1 
ATOM   5412 O O   . SER C 3 166 ? 35.92800 59.78300 72.95800  1.000 79.87000  ?  145  SER R    O   1 
ATOM   5413 C CB  . SER C 3 166 ? 37.88400 61.94900 72.42300  1.000 74.65000  ?  145  SER R    CB  1 
ATOM   5414 O OG  . SER C 3 166 ? 38.70700 61.59600 73.54000  1.000 71.70000  ?  145  SER R    OG  1 
ATOM   5415 N N   . ALA C 3 167 ? 37.65900 58.47500 72.43400  1.000 85.84000  ?  146  ALA R    N   1 
ATOM   5416 C CA  . ALA C 3 167 ? 37.10800 57.39700 73.28000  1.000 86.25000  ?  146  ALA R    CA  1 
ATOM   5417 C C   . ALA C 3 167 ? 36.97100 57.86600 74.72900  1.000 84.36000  ?  146  ALA R    C   1 
ATOM   5418 O O   . ALA C 3 167 ? 35.83600 57.94600 75.20900  1.000 84.06000  ?  146  ALA R    O   1 
ATOM   5419 C CB  . ALA C 3 167 ? 38.00700 56.19600 73.19600  1.000 88.51000  ?  146  ALA R    CB  1 
ATOM   5420 N N   . LYS C 3 168 ? 38.08100 58.19400 75.38500  1.000 81.68000  ?  147  LYS R    N   1 
ATOM   5421 C CA  . LYS C 3 168 ? 38.05700 58.53000 76.83300  1.000 77.94000  ?  147  LYS R    CA  1 
ATOM   5422 C C   . LYS C 3 168 ? 37.18600 59.74800 77.16000  1.000 80.66000  ?  147  LYS R    C   1 
ATOM   5423 O O   . LYS C 3 168 ? 37.40600 60.32200 78.23600  1.000 81.07000  ?  147  LYS R    O   1 
ATOM   5424 C CB  . LYS C 3 168 ? 39.48800 58.78700 77.30700  1.000 81.89000  ?  147  LYS R    CB  1 
ATOM   5425 C CG  . LYS C 3 168 ? 40.45800 57.63800 77.06600  1.000 95.40000  ?  147  LYS R    CG  1 
ATOM   5426 C CD  . LYS C 3 168 ? 41.88000 57.94300 77.48100  1.000 110.71000 ?  147  LYS R    CD  1 
ATOM   5427 C CE  . LYS C 3 168 ? 42.02800 58.18400 78.96800  1.000 117.38000 ?  147  LYS R    CE  1 
ATOM   5428 N NZ  . LYS C 3 168 ? 43.44100 58.42100 79.34300  1.000 123.30000 ?  147  LYS R    NZ  1 
ATOM   5429 N N   . THR C 3 169 ? 36.24200 60.13400 76.30200  1.000 80.67000  ?  148  THR R    N   1 
ATOM   5430 C CA  . THR C 3 169 ? 35.45900 61.37200 76.58500  1.000 71.49000  ?  148  THR R    CA  1 
ATOM   5431 C C   . THR C 3 169 ? 34.11000 61.31400 75.87000  1.000 72.97000  ?  148  THR R    C   1 
ATOM   5432 O O   . THR C 3 169 ? 33.32900 62.25700 76.03600  1.000 68.52000  ?  148  THR R    O   1 
ATOM   5433 C CB  . THR C 3 169 ? 36.14100 62.67000 76.14300  1.000 66.35000  ?  148  THR R    CB  1 
ATOM   5434 O OG1 . THR C 3 169 ? 36.24200 62.63400 74.72100  1.000 68.59000  ?  148  THR R    OG1 1 
ATOM   5435 C CG2 . THR C 3 169 ? 37.50800 62.88900 76.75100  1.000 65.67000  ?  148  THR R    CG2 1 
ATOM   5436 N N   . ARG C 3 170 ? 33.84500 60.25300 75.12000  1.000 71.15000  ?  149  ARG R    N   1 
ATOM   5437 C CA  . ARG C 3 170 ? 32.62600 60.08800 74.33100  1.000 70.91000  ?  149  ARG R    CA  1 
ATOM   5438 C C   . ARG C 3 170 ? 32.38100 61.26900 73.40500  1.000 68.10000  ?  149  ARG R    C   1 
ATOM   5439 O O   . ARG C 3 170 ? 31.31000 61.35100 72.79500  1.000 70.67000  ?  149  ARG R    O   1 
ATOM   5440 C CB  . ARG C 3 170 ? 31.39000 59.87900 75.22200  1.000 75.23000  ?  149  ARG R    CB  1 
ATOM   5441 C CG  . ARG C 3 170 ? 30.37400 58.77000 74.86300  1.000 73.56000  ?  149  ARG R    CG  1 
ATOM   5442 C CD  . ARG C 3 170 ? 29.26500 58.87600 75.91500  1.000 85.88000  ?  149  ARG R    CD  1 
ATOM   5443 N NE  . ARG C 3 170 ? 28.04400 58.07800 75.78300  1.000 103.40000 ?  149  ARG R    NE  1 
ATOM   5444 C CZ  . ARG C 3 170 ? 27.16300 58.10200 74.78800  1.000 104.28000 ?  149  ARG R    CZ  1 
ATOM   5445 N NH1 . ARG C 3 170 ? 27.39800 58.75300 73.65800  1.000 92.76000  ?  149  ARG R    NH1 1 
ATOM   5446 N NH2 . ARG C 3 170 ? 26.01800 57.43400 74.93000  1.000 110.10000 ?  149  ARG R    NH2 1 
ATOM   5447 N N   . GLN C 3 171 ? 33.33900 62.19600 73.28200  1.000 67.99000  ?  150  GLN R    N   1 
ATOM   5448 C CA  . GLN C 3 171 ? 33.12000 63.40600 72.49600  1.000 63.91000  ?  150  GLN R    CA  1 
ATOM   5449 C C   . GLN C 3 171 ? 33.01000 63.04700 71.03800  1.000 67.12000  ?  150  GLN R    C   1 
ATOM   5450 O O   . GLN C 3 171 ? 33.93400 62.47500 70.46100  1.000 68.99000  ?  150  GLN R    O   1 
ATOM   5451 C CB  . GLN C 3 171 ? 34.22700 64.42200 72.71200  1.000 59.86000  ?  150  GLN R    CB  1 
ATOM   5452 C CG  . GLN C 3 171 ? 34.19100 65.02400 74.07800  1.000 60.73000  ?  150  GLN R    CG  1 
ATOM   5453 C CD  . GLN C 3 171 ? 35.24200 66.07400 74.28700  1.000 62.87000  ?  150  GLN R    CD  1 
ATOM   5454 O OE1 . GLN C 3 171 ? 36.38100 65.78200 74.67100  1.000 63.54000  ?  150  GLN R    OE1 1 
ATOM   5455 N NE2 . GLN C 3 171 ? 34.87500 67.32000 74.01700  1.000 62.19000  ?  150  GLN R    NE2 1 
ATOM   5456 N N   . GLY C 3 172 ? 31.83900 63.30800 70.47500  1.000 80.18000  ?  151  GLY R    N   1 
ATOM   5457 C CA  . GLY C 3 172 ? 31.51300 63.08500 69.07000  1.000 81.88000  ?  151  GLY R    CA  1 
ATOM   5458 C C   . GLY C 3 172 ? 31.40200 61.62100 68.64200  1.000 73.47000  ?  151  GLY R    C   1 
ATOM   5459 O O   . GLY C 3 172 ? 31.36500 61.35000 67.45300  1.000 76.35000  ?  151  GLY R    O   1 
ATOM   5460 N N   . VAL C 3 173 ? 31.29400 60.66700 69.56900  1.000 78.02000  ?  152  VAL R    N   1 
ATOM   5461 C CA  . VAL C 3 173 ? 30.93400 59.30500 69.17400  1.000 75.76000  ?  152  VAL R    CA  1 
ATOM   5462 C C   . VAL C 3 173 ? 29.50000 59.31300 68.66300  1.000 78.30000  ?  152  VAL R    C   1 
ATOM   5463 O O   . VAL C 3 173 ? 29.21500 58.89000 67.54100  1.000 74.16000  ?  152  VAL R    O   1 
ATOM   5464 C CB  . VAL C 3 173 ? 31.08400 58.32800 70.35300  1.000 71.10000  ?  152  VAL R    CB  1 
ATOM   5465 C CG1 . VAL C 3 173 ? 30.57500 56.91800 69.96800  1.000 69.34000  ?  152  VAL R    CG1 1 
ATOM   5466 C CG2 . VAL C 3 173 ? 32.51500 58.30200 70.86000  1.000 70.35000  ?  152  VAL R    CG2 1 
ATOM   5467 N N   . ASP C 3 174 ? 28.58500 59.86500 69.45200  1.000 84.02000  ?  153  ASP R    N   1 
ATOM   5468 C CA  . ASP C 3 174 ? 27.18100 59.97200 68.98200  1.000 83.84000  ?  153  ASP R    CA  1 
ATOM   5469 C C   . ASP C 3 174 ? 27.15100 60.73800 67.66100  1.000 77.48000  ?  153  ASP R    C   1 
ATOM   5470 O O   . ASP C 3 174 ? 26.19400 60.55400 66.90200  1.000 80.69000  ?  153  ASP R    O   1 
ATOM   5471 C CB  . ASP C 3 174 ? 26.28400 60.65000 70.01700  1.000 30.00000  ?  153  ASP R    CB  1 
ATOM   5472 C CG  . ASP C 3 174 ? 25.90500 59.75600 71.18200  1.000 30.00000  ?  153  ASP R    CG  1 
ATOM   5473 O OD1 . ASP C 3 174 ? 26.33700 58.58900 71.18800  1.000 30.00000  ?  153  ASP R    OD1 1 
ATOM   5474 O OD2 . ASP C 3 174 ? 25.18000 60.23600 72.07300  1.000 30.00000  ?  153  ASP R    OD2 1 
ATOM   5475 N N   . ASP C 3 175 ? 28.15700 61.57000 67.40400  1.000 79.13000  ?  154  ASP R    N   1 
ATOM   5476 C CA  . ASP C 3 175 ? 28.13700 62.39000 66.19700  1.000 82.59000  ?  154  ASP R    CA  1 
ATOM   5477 C C   . ASP C 3 175 ? 28.54200 61.64000 64.93000  1.000 78.77000  ?  154  ASP R    C   1 
ATOM   5478 O O   . ASP C 3 175 ? 27.89600 61.77400 63.88900  1.000 77.27000  ?  154  ASP R    O   1 
ATOM   5479 C CB  . ASP C 3 175 ? 29.06700 63.57000 66.41000  1.000 86.08000  ?  154  ASP R    CB  1 
ATOM   5480 C CG  . ASP C 3 175 ? 28.69000 64.75000 65.57600  1.000 92.62000  ?  154  ASP R    CG  1 
ATOM   5481 O OD1 . ASP C 3 175 ? 28.09500 64.55900 64.49400  1.000 84.81000  ?  154  ASP R    OD1 1 
ATOM   5482 O OD2 . ASP C 3 175 ? 29.03400 65.87400 65.99600  1.000 108.65000 ?  154  ASP R    OD2 1 
ATOM   5483 N N   . ALA C 3 176 ? 29.64400 60.89000 64.98700  1.000 75.35000  ?  155  ALA R    N   1 
ATOM   5484 C CA  . ALA C 3 176 ? 30.00100 59.98600 63.90200  1.000 73.65000  ?  155  ALA R    CA  1 
ATOM   5485 C C   . ALA C 3 176 ? 28.81300 59.11000 63.48100  1.000 77.10000  ?  155  ALA R    C   1 
ATOM   5486 O O   . ALA C 3 176 ? 28.36500 59.16300 62.33000  1.000 76.69000  ?  155  ALA R    O   1 
ATOM   5487 C CB  . ALA C 3 176 ? 31.20100 59.13900 64.32700  1.000 65.23000  ?  155  ALA R    CB  1 
ATOM   5488 N N   . PHE C 3 177 ? 28.26400 58.31800 64.40900  1.000 73.49000  ?  156  PHE R    N   1 
ATOM   5489 C CA  . PHE C 3 177 ? 27.22400 57.36200 64.04000  1.000 69.41000  ?  156  PHE R    CA  1 
ATOM   5490 C C   . PHE C 3 177 ? 25.98100 58.04600 63.48500  1.000 76.76000  ?  156  PHE R    C   1 
ATOM   5491 O O   . PHE C 3 177 ? 25.48900 57.67200 62.41400  1.000 78.27000  ?  156  PHE R    O   1 
ATOM   5492 C CB  . PHE C 3 177 ? 26.89000 56.47800 65.22800  1.000 68.46000  ?  156  PHE R    CB  1 
ATOM   5493 C CG  . PHE C 3 177 ? 27.96800 55.49700 65.54500  1.000 70.89000  ?  156  PHE R    CG  1 
ATOM   5494 C CD1 . PHE C 3 177 ? 29.04300 55.85700 66.31700  1.000 72.41000  ?  156  PHE R    CD1 1 
ATOM   5495 C CD2 . PHE C 3 177 ? 27.90800 54.20500 65.06400  1.000 71.16000  ?  156  PHE R    CD2 1 
ATOM   5496 C CE1 . PHE C 3 177 ? 30.04500 54.95500 66.60000  1.000 69.13000  ?  156  PHE R    CE1 1 
ATOM   5497 C CE2 . PHE C 3 177 ? 28.90200 53.30300 65.35300  1.000 68.53000  ?  156  PHE R    CE2 1 
ATOM   5498 C CZ  . PHE C 3 177 ? 29.96900 53.68100 66.12300  1.000 68.49000  ?  156  PHE R    CZ  1 
ATOM   5499 N N   . TYR C 3 178 ? 25.46100 59.05600 64.18500  1.000 79.11000  ?  157  TYR R    N   1 
ATOM   5500 C CA  . TYR C 3 178 ? 24.27300 59.76200 63.69500  1.000 82.19000  ?  157  TYR R    CA  1 
ATOM   5501 C C   . TYR C 3 178 ? 24.51000 60.38700 62.31200  1.000 78.70000  ?  157  TYR R    C   1 
ATOM   5502 O O   . TYR C 3 178 ? 23.62100 60.36500 61.45200  1.000 76.40000  ?  157  TYR R    O   1 
ATOM   5503 C CB  . TYR C 3 178 ? 23.84700 60.84400 64.69300  1.000 82.91000  ?  157  TYR R    CB  1 
ATOM   5504 C CG  . TYR C 3 178 ? 23.24300 60.34800 65.98900  1.000 82.42000  ?  157  TYR R    CG  1 
ATOM   5505 C CD1 . TYR C 3 178 ? 23.34200 59.01300 66.37100  1.000 83.38000  ?  157  TYR R    CD1 1 
ATOM   5506 C CD2 . TYR C 3 178 ? 22.62600 61.23200 66.86300  1.000 85.02000  ?  157  TYR R    CD2 1 
ATOM   5507 C CE1 . TYR C 3 178 ? 22.81400 58.56700 67.58800  1.000 88.09000  ?  157  TYR R    CE1 1 
ATOM   5508 C CE2 . TYR C 3 178 ? 22.09600 60.79500 68.07700  1.000 95.35000  ?  157  TYR R    CE2 1 
ATOM   5509 C CZ  . TYR C 3 178 ? 22.19600 59.46200 68.43100  1.000 94.88000  ?  157  TYR R    CZ  1 
ATOM   5510 O OH  . TYR C 3 178 ? 21.67200 59.02800 69.62500  1.000 98.31000  ?  157  TYR R    OH  1 
ATOM   5511 N N   . THR C 3 179 ? 25.69400 60.96400 62.08700  1.000 74.80000  ?  158  THR R    N   1 
ATOM   5512 C CA  . THR C 3 179 ? 26.01900 61.51400 60.77400  1.000 73.41000  ?  158  THR R    CA  1 
ATOM   5513 C C   . THR C 3 179 ? 26.04100 60.44300 59.69000  1.000 77.43000  ?  158  THR R    C   1 
ATOM   5514 O O   . THR C 3 179 ? 25.63000 60.70100 58.55400  1.000 77.04000  ?  158  THR R    O   1 
ATOM   5515 C CB  . THR C 3 179 ? 27.36000 62.23000 60.82000  1.000 71.22000  ?  158  THR R    CB  1 
ATOM   5516 O OG1 . THR C 3 179 ? 27.21200 63.48400 61.48000  1.000 72.15000  ?  158  THR R    OG1 1 
ATOM   5517 C CG2 . THR C 3 179 ? 27.89300 62.45900 59.44800  1.000 77.45000  ?  158  THR R    CG2 1 
ATOM   5518 N N   . LEU C 3 180 ? 26.53500 59.24500 60.00400  1.000 74.98000  ?  159  LEU R    N   1 
ATOM   5519 C CA  . LEU C 3 180 ? 26.49100 58.17300 59.01500  1.000 75.04000  ?  159  LEU R    CA  1 
ATOM   5520 C C   . LEU C 3 180 ? 25.05300 57.85600 58.61700  1.000 77.17000  ?  159  LEU R    C   1 
ATOM   5521 O O   . LEU C 3 180 ? 24.73000 57.77700 57.42800  1.000 77.69000  ?  159  LEU R    O   1 
ATOM   5522 C CB  . LEU C 3 180 ? 27.17700 56.91700 59.54700  1.000 73.53000  ?  159  LEU R    CB  1 
ATOM   5523 C CG  . LEU C 3 180 ? 27.16900 55.75000 58.55300  1.000 70.60000  ?  159  LEU R    CG  1 
ATOM   5524 C CD1 . LEU C 3 180 ? 27.68300 56.16700 57.17400  1.000 70.21000  ?  159  LEU R    CD1 1 
ATOM   5525 C CD2 . LEU C 3 180 ? 27.93000 54.56700 59.05600  1.000 64.81000  ?  159  LEU R    CD2 1 
ATOM   5526 N N   . VAL C 3 181 ? 24.17900 57.65300 59.60600  1.000 75.95000  ?  160  VAL R    N   1 
ATOM   5527 C CA  . VAL C 3 181 ? 22.75000 57.49700 59.33800  1.000 79.48000  ?  160  VAL R    CA  1 
ATOM   5528 C C   . VAL C 3 181 ? 22.22100 58.63100 58.46600  1.000 81.37000  ?  160  VAL R    C   1 
ATOM   5529 O O   . VAL C 3 181 ? 21.35900 58.41500 57.61200  1.000 84.36000  ?  160  VAL R    O   1 
ATOM   5530 C CB  . VAL C 3 181 ? 21.96600 57.39400 60.66900  1.000 86.19000  ?  160  VAL R    CB  1 
ATOM   5531 C CG1 . VAL C 3 181 ? 20.48300 57.31000 60.41200  1.000 84.06000  ?  160  VAL R    CG1 1 
ATOM   5532 C CG2 . VAL C 3 181 ? 22.42500 56.17100 61.50000  1.000 82.30000  ?  160  VAL R    CG2 1 
ATOM   5533 N N   . ARG C 3 182 ? 22.73700 59.84600 58.63900  1.000 80.81000  ?  161  ARG R    N   1 
ATOM   5534 C CA  . ARG C 3 182 ? 22.29300 60.94700 57.78600  1.000 82.46000  ?  161  ARG R    CA  1 
ATOM   5535 C C   . ARG C 3 182 ? 22.72900 60.75200 56.32800  1.000 88.30000  ?  161  ARG R    C   1 
ATOM   5536 O O   . ARG C 3 182 ? 21.94000 60.99900 55.40700  1.000 92.61000  ?  161  ARG R    O   1 
ATOM   5537 C CB  . ARG C 3 182 ? 22.80100 62.27400 58.35100  1.000 79.42000  ?  161  ARG R    CB  1 
ATOM   5538 C CG  . ARG C 3 182 ? 22.26000 62.54700 59.72700  1.000 76.66000  ?  161  ARG R    CG  1 
ATOM   5539 C CD  . ARG C 3 182 ? 22.50500 63.95500 60.22600  1.000 83.99000  ?  161  ARG R    CD  1 
ATOM   5540 N NE  . ARG C 3 182 ? 21.79600 64.15700 61.49000  1.000 95.35000  ?  161  ARG R    NE  1 
ATOM   5541 C CZ  . ARG C 3 182 ? 22.36000 64.34500 62.68200  1.000 92.08000  ?  161  ARG R    CZ  1 
ATOM   5542 N NH1 . ARG C 3 182 ? 23.67100 64.46300 62.82600  1.000 87.89000  ?  161  ARG R    NH1 1 
ATOM   5543 N NH2 . ARG C 3 182 ? 21.58600 64.41300 63.75900  1.000 92.69000  ?  161  ARG R    NH2 1 
ATOM   5544 N N   . GLU C 3 183 ? 23.97500 60.31500 56.09300  1.000 83.69000  ?  162  GLU R    N   1 
ATOM   5545 C CA  . GLU C 3 183 ? 24.42200 60.04400 54.73000  1.000 77.59000  ?  162  GLU R    CA  1 
ATOM   5546 C C   . GLU C 3 183 ? 23.62500 58.90100 54.12400  1.000 83.59000  ?  162  GLU R    C   1 
ATOM   5547 O O   . GLU C 3 183 ? 23.35000 58.89000 52.91900  1.000 86.84000  ?  162  GLU R    O   1 
ATOM   5548 C CB  . GLU C 3 183 ? 25.89800 59.67700 54.71600  1.000 78.12000  ?  162  GLU R    CB  1 
ATOM   5549 C CG  . GLU C 3 183 ? 26.79000 60.74500 55.25600  1.000 87.17000  ?  162  GLU R    CG  1 
ATOM   5550 C CD  . GLU C 3 183 ? 26.74400 62.01600 54.47800  1.000 90.98000  ?  162  GLU R    CD  1 
ATOM   5551 O OE1 . GLU C 3 183 ? 27.27100 62.03000 53.35000  1.000 97.20000  ?  162  GLU R    OE1 1 
ATOM   5552 O OE2 . GLU C 3 183 ? 26.14300 62.99000 54.98400  1.000 96.54000  ?  162  GLU R    OE2 1 
ATOM   5553 N N   . ILE C 3 184 ? 23.26900 57.90600 54.93800  1.000 81.85000  ?  163  ILE R    N   1 
ATOM   5554 C CA  . ILE C 3 184 ? 22.44600 56.80700 54.43800  1.000 84.09000  ?  163  ILE R    CA  1 
ATOM   5555 C C   . ILE C 3 184 ? 21.10300 57.33300 53.96600  1.000 82.70000  ?  163  ILE R    C   1 
ATOM   5556 O O   . ILE C 3 184 ? 20.57100 56.88300 52.94700  1.000 83.79000  ?  163  ILE R    O   1 
ATOM   5557 C CB  . ILE C 3 184 ? 22.29000 55.72000 55.51900  1.000 83.62000  ?  163  ILE R    CB  1 
ATOM   5558 C CG1 . ILE C 3 184 ? 23.65700 55.08500 55.78700  1.000 80.04000  ?  163  ILE R    CG1 1 
ATOM   5559 C CG2 . ILE C 3 184 ? 21.20500 54.69800 55.14600  1.000 72.81000  ?  163  ILE R    CG2 1 
ATOM   5560 C CD1 . ILE C 3 184 ? 23.68100 54.13000 56.93600  1.000 80.35000  ?  163  ILE R    CD1 1 
ATOM   5561 N N   . ARG C 3 185 ? 20.57600 58.31100 54.69600  1.000 82.95000  ?  164  ARG R    N   1 
ATOM   5562 C CA  . ARG C 3 185 ? 19.23500 58.85500 54.37100  1.000 83.34000  ?  164  ARG R    CA  1 
ATOM   5563 C C   . ARG C 3 185 ? 19.32200 59.73800 53.12700  1.000 84.38000  ?  164  ARG R    C   1 
ATOM   5564 O O   . ARG C 3 185 ? 18.57700 60.72200 53.05500  1.000 94.43000  ?  164  ARG R    O   1 
ATOM   5565 C CB  . ARG C 3 185 ? 18.71000 59.64100 55.57400  1.000 86.39000  ?  164  ARG R    CB  1 
ATOM   5566 C CG  . ARG C 3 185 ? 18.31200 58.77400 56.75900  1.000 88.76000  ?  164  ARG R    CG  1 
ATOM   5567 C CD  . ARG C 3 185 ? 17.86600 59.61000 57.94300  1.000 91.88000  ?  164  ARG R    CD  1 
ATOM   5568 N NE  . ARG C 3 185 ? 17.34900 58.80600 59.04000  1.000 98.08000  ?  164  ARG R    NE  1 
ATOM   5569 C CZ  . ARG C 3 185 ? 16.92100 59.30000 60.19500  1.000 99.69000  ?  164  ARG R    CZ  1 
ATOM   5570 N NH1 . ARG C 3 185 ? 17.09800 60.57900 60.47300  1.000 94.85000  ?  164  ARG R    NH1 1 
ATOM   5571 N NH2 . ARG C 3 185 ? 16.32100 58.51200 61.06900  1.000 91.40000  ?  164  ARG R    NH2 1 
ATOM   5572 N N   . GLN D 4 3   ? 39.93200 58.00400 29.36100  1.000 122.85000 ?  3    GLN N    N   1 
ATOM   5573 C CA  . GLN D 4 3   ? 40.75100 56.95300 28.74200  1.000 128.09000 ?  3    GLN N    CA  1 
ATOM   5574 C C   . GLN D 4 3   ? 40.06400 56.15800 27.60600  1.000 127.73000 ?  3    GLN N    C   1 
ATOM   5575 O O   . GLN D 4 3   ? 38.90800 55.75100 27.75500  1.000 129.16000 ?  3    GLN N    O   1 
ATOM   5576 C CB  . GLN D 4 3   ? 41.18000 55.95300 29.78900  1.000 119.73000 ?  3    GLN N    CB  1 
ATOM   5577 C CG  . GLN D 4 3   ? 41.65900 54.70700 29.13300  1.000 114.01000 ?  3    GLN N    CG  1 
ATOM   5578 C CD  . GLN D 4 3   ? 41.78600 53.60300 30.08600  1.000 114.83000 ?  3    GLN N    CD  1 
ATOM   5579 O OE1 . GLN D 4 3   ? 41.90300 53.82600 31.28900  1.000 121.30000 ?  3    GLN N    OE1 1 
ATOM   5580 N NE2 . GLN D 4 3   ? 41.75200 52.38300 29.57600  1.000 112.80000 ?  3    GLN N    NE2 1 
ATOM   5581 N N   . LEU D 4 4   ? 40.78100 55.88500 26.50500  1.000 122.48000 ?  4    LEU N    N   1 
ATOM   5582 C CA  . LEU D 4 4   ? 40.20500 55.18700 25.35900  1.000 120.10000 ?  4    LEU N    CA  1 
ATOM   5583 C C   . LEU D 4 4   ? 41.13400 54.07100 24.86900  1.000 116.78000 ?  4    LEU N    C   1 
ATOM   5584 O O   . LEU D 4 4   ? 42.30700 53.99200 25.24800  1.000 118.61000 ?  4    LEU N    O   1 
ATOM   5585 C CB  . LEU D 4 4   ? 39.91600 56.18100 24.22600  1.000 126.72000 ?  4    LEU N    CB  1 
ATOM   5586 C CG  . LEU D 4 4   ? 39.05500 57.41300 24.54500  1.000 122.87000 ?  4    LEU N    CG  1 
ATOM   5587 C CD1 . LEU D 4 4   ? 38.83000 58.24700 23.28800  1.000 124.84000 ?  4    LEU N    CD1 1 
ATOM   5588 C CD2 . LEU D 4 4   ? 37.72500 57.02300 25.17200  1.000 112.55000 ?  4    LEU N    CD2 1 
ATOM   5589 N N   . VAL D 4 5   ? 40.58800 53.21300 23.99900  1.000 114.28000 ?  5    VAL N    N   1 
ATOM   5590 C CA  . VAL D 4 5   ? 41.29900 52.09800 23.36900  1.000 119.58000 ?  5    VAL N    CA  1 
ATOM   5591 C C   . VAL D 4 5   ? 41.03100 52.08300 21.85500  1.000 122.91000 ?  5    VAL N    C   1 
ATOM   5592 O O   . VAL D 4 5   ? 39.89000 52.27500 21.41400  1.000 117.83000 ?  5    VAL N    O   1 
ATOM   5593 C CB  . VAL D 4 5   ? 40.90400 50.75700 24.03700  1.000 108.63000 ?  5    VAL N    CB  1 
ATOM   5594 C CG1 . VAL D 4 5   ? 41.27700 49.61100 23.17500  1.000 108.96000 ?  5    VAL N    CG1 1 
ATOM   5595 C CG2 . VAL D 4 5   ? 41.63200 50.59400 25.34100  1.000 98.30000  ?  5    VAL N    CG2 1 
ATOM   5596 N N   . GLU D 4 6   ? 42.07900 51.81700 21.05500  1.000 126.42000 ?  6    GLU N    N   1 
ATOM   5597 C CA  . GLU D 4 6   ? 42.08600 52.04700 19.60300  1.000 124.34000 ?  6    GLU N    CA  1 
ATOM   5598 C C   . GLU D 4 6   ? 42.53400 50.78500 18.85000  1.000 117.20000 ?  6    GLU N    C   1 
ATOM   5599 O O   . GLU D 4 6   ? 42.88600 49.77000 19.45400  1.000 121.12000 ?  6    GLU N    O   1 
ATOM   5600 C CB  . GLU D 4 6   ? 42.98000 53.25200 19.28900  1.000 126.77000 ?  6    GLU N    CB  1 
ATOM   5601 C CG  . GLU D 4 6   ? 42.50100 54.52300 20.02300  1.000 138.26000 ?  6    GLU N    CG  1 
ATOM   5602 C CD  . GLU D 4 6   ? 43.47300 55.70300 19.93300  1.000 147.06000 ?  6    GLU N    CD  1 
ATOM   5603 O OE1 . GLU D 4 6   ? 44.64600 55.48600 19.55400  1.000 145.86000 ?  6    GLU N    OE1 1 
ATOM   5604 O OE2 . GLU D 4 6   ? 43.06200 56.85000 20.23900  1.000 150.48000 -1 6    GLU N    OE2 1 
ATOM   5605 N N   . SER D 4 7   ? 42.50400 50.83400 17.51600  1.000 115.13000 ?  7    SER N    N   1 
ATOM   5606 C CA  . SER D 4 7   ? 42.79600 49.64300 16.71500  1.000 118.20000 ?  7    SER N    CA  1 
ATOM   5607 C C   . SER D 4 7   ? 43.28600 50.02800 15.30600  1.000 116.90000 ?  7    SER N    C   1 
ATOM   5608 O O   . SER D 4 7   ? 42.91200 51.07300 14.76400  1.000 114.91000 ?  7    SER N    O   1 
ATOM   5609 C CB  . SER D 4 7   ? 41.56100 48.71700 16.64600  1.000 116.70000 ?  7    SER N    CB  1 
ATOM   5610 O OG  . SER D 4 7   ? 40.96400 48.46200 17.92400  1.000 106.10000 ?  7    SER N    OG  1 
ATOM   5611 N N   . GLY D 4 8   ? 44.13900 49.17400 14.72400  1.000 111.23000 ?  8    GLY N    N   1 
ATOM   5612 C CA  . GLY D 4 8   ? 44.64800 49.38800 13.37900  1.000 108.56000 ?  8    GLY N    CA  1 
ATOM   5613 C C   . GLY D 4 8   ? 44.99600 48.09800 12.65500  1.000 111.70000 ?  8    GLY N    C   1 
ATOM   5614 O O   . GLY D 4 8   ? 45.93300 47.41300 13.07000  1.000 111.67000 ?  8    GLY N    O   1 
ATOM   5615 N N   . GLY D 4 9   ? 44.26900 47.76300 11.57400  1.000 110.76000 ?  9    GLY N    N   1 
ATOM   5616 C CA  . GLY D 4 9   ? 44.37400 46.47500 10.88700  1.000 107.38000 ?  9    GLY N    CA  1 
ATOM   5617 C C   . GLY D 4 9   ? 43.93400 46.48800 9.42900   1.000 114.87000 ?  9    GLY N    C   1 
ATOM   5618 O O   . GLY D 4 9   ? 44.60200 47.14200 8.62700   1.000 125.70000 ?  9    GLY N    O   1 
ATOM   5619 N N   . GLY D 4 10  ? 42.84100 45.79400 9.08500   1.000 107.63000 ?  10   GLY N    N   1 
ATOM   5620 C CA  . GLY D 4 10  ? 42.31500 45.86200 7.70500   1.000 108.77000 ?  10   GLY N    CA  1 
ATOM   5621 C C   . GLY D 4 10  ? 41.94300 44.51100 7.11600   1.000 115.60000 ?  10   GLY N    C   1 
ATOM   5622 O O   . GLY D 4 10  ? 41.56900 43.62200 7.89300   1.000 114.49000 ?  10   GLY N    O   1 
ATOM   5623 N N   . LEU D 4 11  ? 42.02200 44.37000 5.78600   1.000 125.63000 ?  11   LEU N    N   1 
ATOM   5624 C CA  . LEU D 4 11  ? 41.67000 43.09700 5.09300   1.000 125.53000 ?  11   LEU N    CA  1 
ATOM   5625 C C   . LEU D 4 11  ? 42.88700 42.58100 4.32100   1.000 122.53000 ?  11   LEU N    C   1 
ATOM   5626 O O   . LEU D 4 11  ? 43.63900 43.41700 3.78900   1.000 121.89000 ?  11   LEU N    O   1 
ATOM   5627 C CB  . LEU D 4 11  ? 40.49700 43.34600 4.14000   1.000 126.87000 ?  11   LEU N    CB  1 
ATOM   5628 C CG  . LEU D 4 11  ? 40.21800 42.24600 3.11400   1.000 120.47000 ?  11   LEU N    CG  1 
ATOM   5629 C CD1 . LEU D 4 11  ? 38.76200 42.27800 2.67800   1.000 125.67000 ?  11   LEU N    CD1 1 
ATOM   5630 C CD2 . LEU D 4 11  ? 41.12000 42.38900 1.89900   1.000 110.14000 ?  11   LEU N    CD2 1 
ATOM   5631 N N   . VAL D 4 12  ? 43.05500 41.25800 4.24500   1.000 113.82000 ?  12   VAL N    N   1 
ATOM   5632 C CA  . VAL D 4 12  ? 44.25600 40.67900 3.57800   1.000 117.71000 ?  12   VAL N    CA  1 
ATOM   5633 C C   . VAL D 4 12  ? 43.97100 39.22300 3.22300   1.000 115.91000 ?  12   VAL N    C   1 
ATOM   5634 O O   . VAL D 4 12  ? 43.05300 38.65100 3.81900   1.000 110.14000 ?  12   VAL N    O   1 
ATOM   5635 C CB  . VAL D 4 12  ? 45.49800 40.78600 4.47800   1.000 123.51000 ?  12   VAL N    CB  1 
ATOM   5636 C CG1 . VAL D 4 12  ? 45.37200 39.90200 5.70800   1.000 116.58000 ?  12   VAL N    CG1 1 
ATOM   5637 C CG2 . VAL D 4 12  ? 46.77600 40.46700 3.72000   1.000 119.67000 ?  12   VAL N    CG2 1 
ATOM   5638 N N   . GLN D 4 13  ? 44.75700 38.64800 2.31200   1.000 117.19000 ?  13   GLN N    N   1 
ATOM   5639 C CA  . GLN D 4 13  ? 44.51000 37.28500 1.84900   1.000 114.54000 ?  13   GLN N    CA  1 
ATOM   5640 C C   . GLN D 4 13  ? 45.23500 36.25100 2.69800   1.000 117.44000 ?  13   GLN N    C   1 
ATOM   5641 O O   . GLN D 4 13  ? 46.17300 36.56900 3.43200   1.000 119.24000 ?  13   GLN N    O   1 
ATOM   5642 C CB  . GLN D 4 13  ? 44.98500 37.11900 0.41200   1.000 125.19000 ?  13   GLN N    CB  1 
ATOM   5643 C CG  . GLN D 4 13  ? 46.48000 36.75600 0.31200   1.000 124.38000 ?  13   GLN N    CG  1 
ATOM   5644 C CD  . GLN D 4 13  ? 47.16800 37.36600 -0.90500  1.000 130.25000 ?  13   GLN N    CD  1 
ATOM   5645 O OE1 . GLN D 4 13  ? 46.81600 37.06500 -2.05200  1.000 131.49000 ?  13   GLN N    OE1 1 
ATOM   5646 N NE2 . GLN D 4 13  ? 48.16400 38.22100 -0.65700  1.000 125.85000 ?  13   GLN N    NE2 1 
ATOM   5647 N N   . ALA D 4 14  ? 44.83500 34.97900 2.51500   1.000 117.67000 ?  14   ALA N    N   1 
ATOM   5648 C CA  . ALA D 4 14  ? 45.34100 33.83600 3.28100   1.000 112.63000 ?  14   ALA N    CA  1 
ATOM   5649 C C   . ALA D 4 14  ? 46.86300 33.70300 3.31500   1.000 113.65000 ?  14   ALA N    C   1 
ATOM   5650 O O   . ALA D 4 14  ? 47.56000 34.11200 2.38100   1.000 120.62000 ?  14   ALA N    O   1 
ATOM   5651 C CB  . ALA D 4 14  ? 44.80800 32.52800 2.69500   1.000 99.78000  ?  14   ALA N    CB  1 
ATOM   5652 N N   . GLU D 4 15  ? 47.38800 33.16200 4.40900   1.000 110.15000 ?  15   GLU N    N   1 
ATOM   5653 C CA  . GLU D 4 15  ? 48.82600 33.05200 4.67100   1.000 121.16000 ?  15   GLU N    CA  1 
ATOM   5654 C C   . GLU D 4 15  ? 49.45500 34.42900 4.93600   1.000 124.29000 ?  15   GLU N    C   1 
ATOM   5655 O O   . GLU D 4 15  ? 50.68300 34.57900 4.84200   1.000 127.17000 ?  15   GLU N    O   1 
ATOM   5656 C CB  . GLU D 4 15  ? 49.60400 32.33300 3.56400   1.000 121.06000 ?  15   GLU N    CB  1 
ATOM   5657 C CG  . GLU D 4 15  ? 49.11300 30.92200 3.27800   1.000 121.72000 ?  15   GLU N    CG  1 
ATOM   5658 C CD  . GLU D 4 15  ? 49.19200 30.01000 4.49400   1.000 125.67000 ?  15   GLU N    CD  1 
ATOM   5659 O OE1 . GLU D 4 15  ? 50.31500 29.62200 4.89800   1.000 124.41000 ?  15   GLU N    OE1 1 
ATOM   5660 O OE2 . GLU D 4 15  ? 48.11100 29.66000 5.02500   1.000 123.53000 ?  15   GLU N    OE2 1 
ATOM   5661 N N   . GLY D 4 16  ? 48.64900 35.43000 5.30000   1.000 120.12000 ?  16   GLY N    N   1 
ATOM   5662 C CA  . GLY D 4 16  ? 49.11600 36.79500 5.43800   1.000 117.33000 ?  16   GLY N    CA  1 
ATOM   5663 C C   . GLY D 4 16  ? 49.83900 37.06100 6.74600   1.000 115.85000 ?  16   GLY N    C   1 
ATOM   5664 O O   . GLY D 4 16  ? 50.18300 36.15900 7.51400   1.000 115.69000 ?  16   GLY N    O   1 
ATOM   5665 N N   . SER D 4 17  ? 50.07300 38.34800 6.99200   1.000 112.17000 ?  17   SER N    N   1 
ATOM   5666 C CA  . SER D 4 17  ? 50.85000 38.79800 8.13600   1.000 116.29000 ?  17   SER N    CA  1 
ATOM   5667 C C   . SER D 4 17  ? 50.28600 40.12600 8.64900   1.000 120.07000 ?  17   SER N    C   1 
ATOM   5668 O O   . SER D 4 17  ? 50.97100 41.14400 8.74400   1.000 122.74000 ?  17   SER N    O   1 
ATOM   5669 C CB  . SER D 4 17  ? 52.33500 38.91700 7.78300   1.000 117.12000 ?  17   SER N    CB  1 
ATOM   5670 O OG  . SER D 4 17  ? 52.98600 37.65900 7.83800   1.000 117.53000 ?  17   SER N    OG  1 
ATOM   5671 N N   . LEU D 4 18  ? 49.00900 40.11300 9.01900   1.000 114.93000 ?  18   LEU N    N   1 
ATOM   5672 C CA  . LEU D 4 18  ? 48.36900 41.31400 9.54300   1.000 114.12000 ?  18   LEU N    CA  1 
ATOM   5673 C C   . LEU D 4 18  ? 48.78100 41.61400 10.99100  1.000 116.35000 ?  18   LEU N    C   1 
ATOM   5674 O O   . LEU D 4 18  ? 48.81400 40.71800 11.84500  1.000 115.53000 ?  18   LEU N    O   1 
ATOM   5675 C CB  . LEU D 4 18  ? 46.85900 41.16100 9.40900   1.000 108.91000 ?  18   LEU N    CB  1 
ATOM   5676 C CG  . LEU D 4 18  ? 46.03300 42.43400 9.43700   1.000 111.51000 ?  18   LEU N    CG  1 
ATOM   5677 C CD1 . LEU D 4 18  ? 46.66700 43.54800 8.65100   1.000 114.72000 ?  18   LEU N    CD1 1 
ATOM   5678 C CD2 . LEU D 4 18  ? 44.72900 42.06100 8.77700   1.000 107.55000 ?  18   LEU N    CD2 1 
ATOM   5679 N N   . ARG D 4 19  ? 49.10700 42.88500 11.25900  1.000 110.78000 ?  19   ARG N    N   1 
ATOM   5680 C CA  . ARG D 4 19  ? 49.45700 43.36200 12.59600  1.000 108.21000 ?  19   ARG N    CA  1 
ATOM   5681 C C   . ARG D 4 19  ? 48.44000 44.38300 13.09300  1.000 110.44000 ?  19   ARG N    C   1 
ATOM   5682 O O   . ARG D 4 19  ? 48.00600 45.26100 12.34100  1.000 116.17000 ?  19   ARG N    O   1 
ATOM   5683 C CB  . ARG D 4 19  ? 50.84500 43.97700 12.62100  1.000 105.19000 ?  19   ARG N    CB  1 
ATOM   5684 C CG  . ARG D 4 19  ? 51.46700 44.06700 13.97900  1.000 99.17000  ?  19   ARG N    CG  1 
ATOM   5685 C CD  . ARG D 4 19  ? 52.18600 45.38700 14.10800  1.000 104.92000 ?  19   ARG N    CD  1 
ATOM   5686 N NE  . ARG D 4 19  ? 53.45700 45.25400 14.81300  1.000 109.94000 ?  19   ARG N    NE  1 
ATOM   5687 C CZ  . ARG D 4 19  ? 54.21300 46.28300 15.17700  1.000 114.78000 ?  19   ARG N    CZ  1 
ATOM   5688 N NH1 . ARG D 4 19  ? 53.89700 47.52600 14.83200  1.000 117.26000 ?  19   ARG N    NH1 1 
ATOM   5689 N NH2 . ARG D 4 19  ? 55.31400 46.06100 15.89800  1.000 107.99000 ?  19   ARG N    NH2 1 
ATOM   5690 N N   . LEU D 4 20  ? 48.07600 44.25900 14.37300  1.000 108.69000 ?  20   LEU N    N   1 
ATOM   5691 C CA  . LEU D 4 20  ? 47.00500 45.01300 15.01000  1.000 101.73000 ?  20   LEU N    CA  1 
ATOM   5692 C C   . LEU D 4 20  ? 47.56300 45.87500 16.13400  1.000 104.61000 ?  20   LEU N    C   1 
ATOM   5693 O O   . LEU D 4 20  ? 48.54300 45.49800 16.78300  1.000 100.14000 ?  20   LEU N    O   1 
ATOM   5694 C CB  . LEU D 4 20  ? 45.95100 44.07100 15.57400  1.000 94.76000  ?  20   LEU N    CB  1 
ATOM   5695 C CG  . LEU D 4 20  ? 44.99600 43.25500 14.71300  1.000 89.72000  ?  20   LEU N    CG  1 
ATOM   5696 C CD1 . LEU D 4 20  ? 44.22500 44.19800 13.87200  1.000 94.52000  ?  20   LEU N    CD1 1 
ATOM   5697 C CD2 . LEU D 4 20  ? 45.75100 42.28100 13.85800  1.000 101.98000 ?  20   LEU N    CD2 1 
ATOM   5698 N N   . SER D 4 21  ? 46.91900 47.02400 16.38300  1.000 101.94000 ?  21   SER N    N   1 
ATOM   5699 C CA  . SER D 4 21  ? 47.40300 47.97700 17.37900  1.000 107.52000 ?  21   SER N    CA  1 
ATOM   5700 C C   . SER D 4 21  ? 46.31100 48.39700 18.37500  1.000 114.88000 ?  21   SER N    C   1 
ATOM   5701 O O   . SER D 4 21  ? 45.11100 48.27100 18.10000  1.000 111.11000 ?  21   SER N    O   1 
ATOM   5702 C CB  . SER D 4 21  ? 47.98700 49.20900 16.68300  1.000 101.47000 ?  21   SER N    CB  1 
ATOM   5703 O OG  . SER D 4 21  ? 48.85700 48.80100 15.65700  1.000 107.07000 ?  21   SER N    OG  1 
ATOM   5704 N N   . CYS D 4 22  ? 46.77300 48.95100 19.50100  1.000 110.23000 ?  22   CYS N    N   1 
ATOM   5705 C CA  . CYS D 4 22  ? 45.86000 49.48200 20.53800  1.000 110.28000 ?  22   CYS N    CA  1 
ATOM   5706 C C   . CYS D 4 22  ? 46.56600 50.66200 21.19700  1.000 108.64000 ?  22   CYS N    C   1 
ATOM   5707 O O   . CYS D 4 22  ? 47.75500 50.51500 21.51400  1.000 105.64000 ?  22   CYS N    O   1 
ATOM   5708 C CB  . CYS D 4 22  ? 45.67600 48.48800 21.66700  1.000 105.76000 ?  22   CYS N    CB  1 
ATOM   5709 S SG  . CYS D 4 22  ? 44.70500 47.03300 21.22300  1.000 123.02000 ?  22   CYS N    SG  1 
ATOM   5710 N N   . LEU D 4 23  ? 45.87800 51.78500 21.38500  1.000 111.67000 ?  23   LEU N    N   1 
ATOM   5711 C CA  . LEU D 4 23  ? 46.50200 52.89800 22.14600  1.000 120.05000 ?  23   LEU N    CA  1 
ATOM   5712 C C   . LEU D 4 23  ? 45.73100 53.03900 23.45700  1.000 119.56000 ?  23   LEU N    C   1 
ATOM   5713 O O   . LEU D 4 23  ? 44.52300 53.32200 23.39800  1.000 124.24000 ?  23   LEU N    O   1 
ATOM   5714 C CB  . LEU D 4 23  ? 46.46600 54.18200 21.31700  1.000 120.72000 ?  23   LEU N    CB  1 
ATOM   5715 C CG  . LEU D 4 23  ? 47.52500 54.27400 20.22100  1.000 109.27000 ?  23   LEU N    CG  1 
ATOM   5716 C CD1 . LEU D 4 23  ? 47.84600 55.72500 19.90300  1.000 106.43000 ?  23   LEU N    CD1 1 
ATOM   5717 C CD2 . LEU D 4 23  ? 48.78600 53.52500 20.62400  1.000 108.40000 ?  23   LEU N    CD2 1 
ATOM   5718 N N   . VAL D 4 24  ? 46.40500 52.85400 24.59100  1.000 112.85000 ?  24   VAL N    N   1 
ATOM   5719 C CA  . VAL D 4 24  ? 45.66800 52.84100 25.88600  1.000 118.41000 ?  24   VAL N    CA  1 
ATOM   5720 C C   . VAL D 4 24  ? 45.47300 54.26900 26.39500  1.000 120.82000 ?  24   VAL N    C   1 
ATOM   5721 O O   . VAL D 4 24  ? 44.83600 54.42600 27.45000  1.000 111.63000 ?  24   VAL N    O   1 
ATOM   5722 C CB  . VAL D 4 24  ? 46.39700 51.97400 26.92500  1.000 121.20000 ?  24   VAL N    CB  1 
ATOM   5723 C CG1 . VAL D 4 24  ? 46.70500 50.59100 26.37500  1.000 125.66000 ?  24   VAL N    CG1 1 
ATOM   5724 C CG2 . VAL D 4 24  ? 47.66600 52.64500 27.42200  1.000 122.99000 ?  24   VAL N    CG2 1 
ATOM   5725 N N   . SER D 4 25  ? 45.98200 55.26700 25.67600  1.000 128.18000 ?  25   SER N    N   1 
ATOM   5726 C CA  . SER D 4 25  ? 45.72100 56.66300 26.10400  1.000 123.90000 ?  25   SER N    CA  1 
ATOM   5727 C C   . SER D 4 25  ? 45.85600 56.76700 27.62800  1.000 118.88000 ?  25   SER N    C   1 
ATOM   5728 O O   . SER D 4 25  ? 44.82300 57.01400 28.28300  1.000 114.93000 ?  25   SER N    O   1 
ATOM   5729 C CB  . SER D 4 25  ? 44.35900 57.10200 25.65200  1.000 117.84000 ?  25   SER N    CB  1 
ATOM   5730 O OG  . SER D 4 25  ? 43.34900 56.28100 26.21800  1.000 119.12000 ?  25   SER N    OG  1 
ATOM   5731 N N   . ARG D 4 30  ? 48.35100 49.67600 36.31000  1.000 80.57000  ?  30   ARG N    N   1 
ATOM   5732 C CA  . ARG D 4 30  ? 49.63200 48.96400 36.46400  1.000 101.31000 ?  30   ARG N    CA  1 
ATOM   5733 C C   . ARG D 4 30  ? 49.53700 47.47100 36.81900  1.000 104.51000 ?  30   ARG N    C   1 
ATOM   5734 O O   . ARG D 4 30  ? 50.18500 46.62300 36.20100  1.000 102.29000 ?  30   ARG N    O   1 
ATOM   5735 C CB  . ARG D 4 30  ? 50.49200 49.61600 37.54200  1.000 114.41000 ?  30   ARG N    CB  1 
ATOM   5736 C CG  . ARG D 4 30  ? 51.66200 48.70700 37.90800  1.000 122.83000 ?  30   ARG N    CG  1 
ATOM   5737 C CD  . ARG D 4 30  ? 52.93900 49.44500 38.23300  1.000 135.33000 ?  30   ARG N    CD  1 
ATOM   5738 N NE  . ARG D 4 30  ? 53.94800 48.54100 38.78600  1.000 144.34000 ?  30   ARG N    NE  1 
ATOM   5739 C CZ  . ARG D 4 30  ? 54.02800 48.16300 40.05900  1.000 145.22000 ?  30   ARG N    CZ  1 
ATOM   5740 N NH1 . ARG D 4 30  ? 53.17500 48.60600 40.97100  1.000 135.25000 ?  30   ARG N    NH1 1 
ATOM   5741 N NH2 . ARG D 4 30  ? 54.99000 47.31900 40.42500  1.000 144.85000 ?  30   ARG N    NH2 1 
ATOM   5742 N N   . SER D 4 31  ? 48.79900 47.16100 37.88300  1.000 105.91000 ?  31   SER N    N   1 
ATOM   5743 C CA  . SER D 4 31  ? 48.38600 45.78300 38.15000  1.000 104.26000 ?  31   SER N    CA  1 
ATOM   5744 C C   . SER D 4 31  ? 47.14700 45.53800 37.28300  1.000 101.24000 ?  31   SER N    C   1 
ATOM   5745 O O   . SER D 4 31  ? 45.99500 45.59000 37.74200  1.000 91.81000  ?  31   SER N    O   1 
ATOM   5746 C CB  . SER D 4 31  ? 48.12100 45.57200 39.64400  1.000 104.95000 ?  31   SER N    CB  1 
ATOM   5747 O OG  . SER D 4 31  ? 47.83000 44.21500 39.98600  1.000 92.55000  ?  31   SER N    OG  1 
ATOM   5748 N N   . ASN D 4 32  ? 47.41900 45.31400 35.99000  1.000 100.25000 ?  32   ASN N    N   1 
ATOM   5749 C CA  . ASN D 4 32  ? 46.32000 45.15400 35.00700  1.000 90.14000  ?  32   ASN N    CA  1 
ATOM   5750 C C   . ASN D 4 32  ? 46.52300 43.91500 34.14300  1.000 85.60000  ?  32   ASN N    C   1 
ATOM   5751 O O   . ASN D 4 32  ? 47.51000 43.19600 34.35800  1.000 89.58000  ?  32   ASN N    O   1 
ATOM   5752 C CB  . ASN D 4 32  ? 46.30700 46.31600 34.02400  1.000 83.17000  ?  32   ASN N    CB  1 
ATOM   5753 C CG  . ASN D 4 32  ? 47.61500 46.45600 33.27500  1.000 90.48000  ?  32   ASN N    CG  1 
ATOM   5754 O OD1 . ASN D 4 32  ? 48.02600 45.55200 32.55200  1.000 87.92000  ?  32   ASN N    OD1 1 
ATOM   5755 N ND2 . ASN D 4 32  ? 48.27900 47.58800 33.44300  1.000 97.39000  ?  32   ASN N    ND2 1 
ATOM   5756 N N   . LEU D 4 33  ? 45.62400 43.70800 33.18300  1.000 80.14000  ?  33   LEU N    N   1 
ATOM   5757 C CA  . LEU D 4 33  ? 45.73800 42.55800 32.25400  1.000 86.41000  ?  33   LEU N    CA  1 
ATOM   5758 C C   . LEU D 4 33  ? 45.02900 42.93900 30.95300  1.000 80.63000  ?  33   LEU N    C   1 
ATOM   5759 O O   . LEU D 4 33  ? 43.93700 43.52400 31.03000  1.000 77.91000  ?  33   LEU N    O   1 
ATOM   5760 C CB  . LEU D 4 33  ? 45.12500 41.32200 32.92200  1.000 80.15000  ?  33   LEU N    CB  1 
ATOM   5761 C CG  . LEU D 4 33  ? 43.62200 41.11900 32.75400  1.000 65.58000  ?  33   LEU N    CG  1 
ATOM   5762 C CD1 . LEU D 4 33  ? 43.33000 40.31200 31.49900  1.000 78.79000  ?  33   LEU N    CD1 1 
ATOM   5763 C CD2 . LEU D 4 33  ? 43.04200 40.42100 33.97200  1.000 65.53000  ?  33   LEU N    CD2 1 
ATOM   5764 N N   . MET D 4 34  ? 45.65200 42.66300 29.80600  1.000 80.82000  ?  34   MET N    N   1 
ATOM   5765 C CA  . MET D 4 34  ? 45.04700 43.04200 28.53400  1.000 82.53000  ?  34   MET N    CA  1 
ATOM   5766 C C   . MET D 4 34  ? 45.17800 41.93200 27.50000  1.000 81.72000  ?  34   MET N    C   1 
ATOM   5767 O O   . MET D 4 34  ? 46.07600 41.08900 27.56700  1.000 83.49000  ?  34   MET N    O   1 
ATOM   5768 C CB  . MET D 4 34  ? 45.65700 44.31200 27.94700  1.000 85.71000  ?  34   MET N    CB  1 
ATOM   5769 C CG  . MET D 4 34  ? 47.17700 44.38500 27.96300  1.000 95.54000  ?  34   MET N    CG  1 
ATOM   5770 S SD  . MET D 4 34  ? 47.69600 46.12000 27.85400  1.000 107.04000 ?  34   MET N    SD  1 
ATOM   5771 C CE  . MET D 4 34  ? 46.44500 46.73100 26.71600  1.000 83.82000  ?  34   MET N    CE  1 
ATOM   5772 N N   . GLY D 4 35  ? 44.27300 41.96800 26.52800  1.000 81.73000  ?  35   GLY N    N   1 
ATOM   5773 C CA  . GLY D 4 35  ? 44.21800 40.93800 25.51200  1.000 84.69000  ?  35   GLY N    CA  1 
ATOM   5774 C C   . GLY D 4 35  ? 43.38900 41.30200 24.28200  1.000 84.92000  ?  35   GLY N    C   1 
ATOM   5775 O O   . GLY D 4 35  ? 43.03000 42.46500 24.05200  1.000 79.52000  ?  35   GLY N    O   1 
ATOM   5776 N N   . TRP D 4 36  ? 43.12000 40.26100 23.48200  1.000 84.09000  ?  36   TRP N    N   1 
ATOM   5777 C CA  . TRP D 4 36  ? 42.41300 40.36100 22.21400  1.000 81.96000  ?  36   TRP N    CA  1 
ATOM   5778 C C   . TRP D 4 36  ? 41.25800 39.38300 22.22500  1.000 81.46000  ?  36   TRP N    C   1 
ATOM   5779 O O   . TRP D 4 36  ? 41.32900 38.31300 22.83000  1.000 80.91000  ?  36   TRP N    O   1 
ATOM   5780 C CB  . TRP D 4 36  ? 43.31600 40.06400 20.99300  1.000 76.56000  ?  36   TRP N    CB  1 
ATOM   5781 C CG  . TRP D 4 36  ? 44.40300 41.04000 20.78600  1.000 80.39000  ?  36   TRP N    CG  1 
ATOM   5782 C CD1 . TRP D 4 36  ? 45.67800 40.94600 21.24200  1.000 84.88000  ?  36   TRP N    CD1 1 
ATOM   5783 C CD2 . TRP D 4 36  ? 44.31000 42.29400 20.09300  1.000 81.22000  ?  36   TRP N    CD2 1 
ATOM   5784 N NE1 . TRP D 4 36  ? 46.39200 42.06200 20.87100  1.000 89.42000  ?  36   TRP N    NE1 1 
ATOM   5785 C CE2 . TRP D 4 36  ? 45.57400 42.90300 20.16600  1.000 85.31000  ?  36   TRP N    CE2 1 
ATOM   5786 C CE3 . TRP D 4 36  ? 43.27600 42.96200 19.42600  1.000 81.18000  ?  36   TRP N    CE3 1 
ATOM   5787 C CZ2 . TRP D 4 36  ? 45.83600 44.14400 19.59600  1.000 88.88000  ?  36   TRP N    CZ2 1 
ATOM   5788 C CZ3 . TRP D 4 36  ? 43.53600 44.19500 18.86500  1.000 77.21000  ?  36   TRP N    CZ3 1 
ATOM   5789 C CH2 . TRP D 4 36  ? 44.80600 44.77400 18.95400  1.000 83.66000  ?  36   TRP N    CH2 1 
ATOM   5790 N N   . TYR D 4 37  ? 40.18800 39.77000 21.55300  1.000 84.19000  ?  37   TYR N    N   1 
ATOM   5791 C CA  . TYR D 4 37  ? 39.01900 38.92700 21.37900  1.000 86.96000  ?  37   TYR N    CA  1 
ATOM   5792 C C   . TYR D 4 37  ? 38.54800 39.15200 19.95900  1.000 89.64000  ?  37   TYR N    C   1 
ATOM   5793 O O   . TYR D 4 37  ? 38.77300 40.22400 19.39900  1.000 92.26000  ?  37   TYR N    O   1 
ATOM   5794 C CB  . TYR D 4 37  ? 37.90300 39.26000 22.40100  1.000 86.05000  ?  37   TYR N    CB  1 
ATOM   5795 C CG  . TYR D 4 37  ? 38.33400 39.13500 23.85800  1.000 83.93000  ?  37   TYR N    CG  1 
ATOM   5796 C CD1 . TYR D 4 37  ? 39.17300 40.07800 24.44000  1.000 79.55000  ?  37   TYR N    CD1 1 
ATOM   5797 C CD2 . TYR D 4 37  ? 37.87500 38.09500 24.65300  1.000 80.41000  ?  37   TYR N    CD2 1 
ATOM   5798 C CE1 . TYR D 4 37  ? 39.58000 39.96500 25.74800  1.000 79.84000  ?  37   TYR N    CE1 1 
ATOM   5799 C CE2 . TYR D 4 37  ? 38.26900 37.97900 25.97100  1.000 80.83000  ?  37   TYR N    CE2 1 
ATOM   5800 C CZ  . TYR D 4 37  ? 39.12600 38.92100 26.52400  1.000 83.36000  ?  37   TYR N    CZ  1 
ATOM   5801 O OH  . TYR D 4 37  ? 39.52800 38.82700 27.85700  1.000 83.32000  ?  37   TYR N    OH  1 
ATOM   5802 N N   . ARG D 4 38  ? 37.92500 38.13800 19.36500  1.000 89.59000  ?  38   ARG N    N   1 
ATOM   5803 C CA  . ARG D 4 38  ? 37.38500 38.28400 18.02500  1.000 93.83000  ?  38   ARG N    CA  1 
ATOM   5804 C C   . ARG D 4 38  ? 35.95700 37.76600 17.99400  1.000 93.67000  ?  38   ARG N    C   1 
ATOM   5805 O O   . ARG D 4 38  ? 35.61200 36.81500 18.70100  1.000 91.28000  ?  38   ARG N    O   1 
ATOM   5806 C CB  . ARG D 4 38  ? 38.23400 37.55100 16.99500  1.000 92.78000  ?  38   ARG N    CB  1 
ATOM   5807 C CG  . ARG D 4 38  ? 38.42900 36.12300 17.33900  1.000 91.65000  ?  38   ARG N    CG  1 
ATOM   5808 C CD  . ARG D 4 38  ? 39.03500 35.32700 16.21300  1.000 92.51000  ?  38   ARG N    CD  1 
ATOM   5809 N NE  . ARG D 4 38  ? 38.94300 33.90600 16.51800  1.000 96.93000  ?  38   ARG N    NE  1 
ATOM   5810 C CZ  . ARG D 4 38  ? 39.77700 32.99100 16.05000  1.000 98.40000  ?  38   ARG N    CZ  1 
ATOM   5811 N NH1 . ARG D 4 38  ? 40.78400 33.32000 15.25700  1.000 92.98000  ?  38   ARG N    NH1 1 
ATOM   5812 N NH2 . ARG D 4 38  ? 39.63000 31.72400 16.43200  1.000 99.97000  ?  38   ARG N    NH2 1 
ATOM   5813 N N   . GLN D 4 39  ? 35.12300 38.41200 17.17600  1.000 93.78000  ?  39   GLN N    N   1 
ATOM   5814 C CA  . GLN D 4 39  ? 33.74000 37.98700 16.96500  1.000 96.77000  ?  39   GLN N    CA  1 
ATOM   5815 C C   . GLN D 4 39  ? 33.54700 37.65500 15.49000  1.000 98.90000  ?  39   GLN N    C   1 
ATOM   5816 O O   . GLN D 4 39  ? 33.45100 38.55400 14.64800  1.000 96.85000  ?  39   GLN N    O   1 
ATOM   5817 C CB  . GLN D 4 39  ? 32.75000 39.05400 17.41200  1.000 98.95000  ?  39   GLN N    CB  1 
ATOM   5818 C CG  . GLN D 4 39  ? 31.29600 38.65200 17.21000  1.000 100.67000 ?  39   GLN N    CG  1 
ATOM   5819 C CD  . GLN D 4 39  ? 30.45200 38.96400 18.42600  1.000 101.51000 ?  39   GLN N    CD  1 
ATOM   5820 O OE1 . GLN D 4 39  ? 30.67400 39.96400 19.10600  1.000 99.83000  ?  39   GLN N    OE1 1 
ATOM   5821 N NE2 . GLN D 4 39  ? 29.48200 38.10200 18.71400  1.000 102.47000 ?  39   GLN N    NE2 1 
ATOM   5822 N N   . ALA D 4 40  ? 33.50400 36.35000 15.19000  1.000 101.17000 ?  40   ALA N    N   1 
ATOM   5823 C CA  . ALA D 4 40  ? 33.09800 35.80200 13.90700  1.000 100.05000 ?  40   ALA N    CA  1 
ATOM   5824 C C   . ALA D 4 40  ? 31.58400 35.92400 13.76300  1.000 107.00000 ?  40   ALA N    C   1 
ATOM   5825 O O   . ALA D 4 40  ? 30.84900 35.66700 14.72300  1.000 103.57000 ?  40   ALA N    O   1 
ATOM   5826 C CB  . ALA D 4 40  ? 33.51500 34.33900 13.79000  1.000 99.72000  ?  40   ALA N    CB  1 
ATOM   5827 N N   . PRO D 4 41  ? 31.09800 36.32300 12.58600  1.000 113.51000 ?  41   PRO N    N   1 
ATOM   5828 C CA  . PRO D 4 41  ? 29.67400 36.66600 12.45400  1.000 109.87000 ?  41   PRO N    CA  1 
ATOM   5829 C C   . PRO D 4 41  ? 28.77600 35.45600 12.65400  1.000 106.54000 ?  41   PRO N    C   1 
ATOM   5830 O O   . PRO D 4 41  ? 29.05400 34.35900 12.16400  1.000 103.52000 ?  41   PRO N    O   1 
ATOM   5831 C CB  . PRO D 4 41  ? 29.57300 37.21900 11.02900  1.000 102.65000 ?  41   PRO N    CB  1 
ATOM   5832 C CG  . PRO D 4 41  ? 30.78700 36.68900 10.33300  1.000 104.44000 ?  41   PRO N    CG  1 
ATOM   5833 C CD  . PRO D 4 41  ? 31.85700 36.58300 11.35100  1.000 102.54000 ?  41   PRO N    CD  1 
ATOM   5834 N N   . GLY D 4 42  ? 27.69400 35.66900 13.39900  1.000 107.15000 ?  42   GLY N    N   1 
ATOM   5835 C CA  . GLY D 4 42  ? 26.78400 34.60000 13.75200  1.000 111.27000 ?  42   GLY N    CA  1 
ATOM   5836 C C   . GLY D 4 42  ? 27.27200 33.67900 14.84300  1.000 112.24000 ?  42   GLY N    C   1 
ATOM   5837 O O   . GLY D 4 42  ? 26.54800 32.74700 15.21700  1.000 112.31000 ?  42   GLY N    O   1 
ATOM   5838 N N   . LYS D 4 43  ? 28.46700 33.91600 15.37600  1.000 115.59000 ?  43   LYS N    N   1 
ATOM   5839 C CA  . LYS D 4 43  ? 29.06700 33.07600 16.39900  1.000 114.90000 ?  43   LYS N    CA  1 
ATOM   5840 C C   . LYS D 4 43  ? 29.35100 33.91000 17.65400  1.000 111.36000 ?  43   LYS N    C   1 
ATOM   5841 O O   . LYS D 4 43  ? 29.36300 35.14900 17.61800  1.000 105.96000 ?  43   LYS N    O   1 
ATOM   5842 C CB  . LYS D 4 43  ? 30.34000 32.40600 15.83800  1.000 108.59000 ?  43   LYS N    CB  1 
ATOM   5843 C CG  . LYS D 4 43  ? 31.01600 31.38500 16.74600  1.000 110.13000 ?  43   LYS N    CG  1 
ATOM   5844 C CD  . LYS D 4 43  ? 31.99200 30.49700 15.95600  1.000 119.54000 ?  43   LYS N    CD  1 
ATOM   5845 C CE  . LYS D 4 43  ? 32.36100 31.07800 14.58100  1.000 109.31000 ?  43   LYS N    CE  1 
ATOM   5846 N NZ  . LYS D 4 43  ? 33.63300 30.49700 14.06400  1.000 99.70000  ?  43   LYS N    NZ  1 
ATOM   5847 N N   . GLN D 4 44  ? 29.54500 33.20900 18.77600  1.000 104.70000 ?  44   GLN N    N   1 
ATOM   5848 C CA  . GLN D 4 44  ? 29.77700 33.84600 20.06800  1.000 96.64000  ?  44   GLN N    CA  1 
ATOM   5849 C C   . GLN D 4 44  ? 31.15700 34.47000 20.12600  1.000 94.58000  ?  44   GLN N    C   1 
ATOM   5850 O O   . GLN D 4 44  ? 32.10600 33.98100 19.51000  1.000 97.45000  ?  44   GLN N    O   1 
ATOM   5851 C CB  . GLN D 4 44  ? 29.64700 32.82300 21.19000  1.000 98.56000  ?  44   GLN N    CB  1 
ATOM   5852 C CG  . GLN D 4 44  ? 30.12700 33.29900 22.54400  1.000 93.14000  ?  44   GLN N    CG  1 
ATOM   5853 C CD  . GLN D 4 44  ? 30.15800 32.19300 23.59000  1.000 99.32000  ?  44   GLN N    CD  1 
ATOM   5854 O OE1 . GLN D 4 44  ? 30.27000 31.00100 23.27200  1.000 105.96000 ?  44   GLN N    OE1 1 
ATOM   5855 N NE2 . GLN D 4 44  ? 30.02700 32.58500 24.85100  1.000 94.36000  ?  44   GLN N    NE2 1 
ATOM   5856 N N   . ARG D 4 45  ? 31.27000 35.56000 20.87800  1.000 91.32000  ?  45   ARG N    N   1 
ATOM   5857 C CA  . ARG D 4 45  ? 32.57300 36.18500 21.03700  1.000 91.95000  ?  45   ARG N    CA  1 
ATOM   5858 C C   . ARG D 4 45  ? 33.55300 35.19900 21.65800  1.000 89.16000  ?  45   ARG N    C   1 
ATOM   5859 O O   . ARG D 4 45  ? 33.17500 34.33100 22.44700  1.000 92.35000  ?  45   ARG N    O   1 
ATOM   5860 C CB  . ARG D 4 45  ? 32.46900 37.44800 21.88200  1.000 86.78000  ?  45   ARG N    CB  1 
ATOM   5861 C CG  . ARG D 4 45  ? 33.69700 38.32300 21.79600  1.000 86.52000  ?  45   ARG N    CG  1 
ATOM   5862 C CD  . ARG D 4 45  ? 33.49300 39.50200 22.66400  1.000 87.20000  ?  45   ARG N    CD  1 
ATOM   5863 N NE  . ARG D 4 45  ? 32.34000 40.28000 22.23000  1.000 88.49000  ?  45   ARG N    NE  1 
ATOM   5864 C CZ  . ARG D 4 45  ? 32.41200 41.53200 21.80100  1.000 89.00000  ?  45   ARG N    CZ  1 
ATOM   5865 N NH1 . ARG D 4 45  ? 33.55500 42.19200 21.79100  1.000 87.45000  ?  45   ARG N    NH1 1 
ATOM   5866 N NH2 . ARG D 4 45  ? 31.30100 42.15400 21.42400  1.000 88.10000  ?  45   ARG N    NH2 1 
ATOM   5867 N N   . GLU D 4 46  ? 34.82000 35.32600 21.27500  1.000 85.34000  ?  46   GLU N    N   1 
ATOM   5868 C CA  . GLU D 4 46  ? 35.84200 34.32700 21.55000  1.000 85.12000  ?  46   GLU N    CA  1 
ATOM   5869 C C   . GLU D 4 46  ? 37.07000 35.04100 22.08500  1.000 84.38000  ?  46   GLU N    C   1 
ATOM   5870 O O   . GLU D 4 46  ? 37.40500 36.14800 21.64900  1.000 82.21000  ?  46   GLU N    O   1 
ATOM   5871 C CB  . GLU D 4 46  ? 36.21100 33.54800 20.26700  1.000 95.32000  ?  46   GLU N    CB  1 
ATOM   5872 C CG  . GLU D 4 46  ? 37.05500 32.25100 20.37000  1.000 96.90000  ?  46   GLU N    CG  1 
ATOM   5873 C CD  . GLU D 4 46  ? 37.34800 31.62600 18.95400  1.000 110.62000 ?  46   GLU N    CD  1 
ATOM   5874 O OE1 . GLU D 4 46  ? 36.44900 30.99100 18.35000  1.000 117.64000 ?  46   GLU N    OE1 1 
ATOM   5875 O OE2 . GLU D 4 46  ? 38.48800 31.77500 18.43500  1.000 101.76000 -1 46   GLU N    OE2 1 
ATOM   5876 N N   . PHE D 4 47  ? 37.71700 34.40800 23.04700  1.000 83.76000  ?  47   PHE N    N   1 
ATOM   5877 C CA  . PHE D 4 47  ? 39.02000 34.83800 23.51800  1.000 82.84000  ?  47   PHE N    CA  1 
ATOM   5878 C C   . PHE D 4 47  ? 40.06300 34.35800 22.52700  1.000 83.96000  ?  47   PHE N    C   1 
ATOM   5879 O O   . PHE D 4 47  ? 39.98000 33.22600 22.03600  1.000 84.36000  ?  47   PHE N    O   1 
ATOM   5880 C CB  . PHE D 4 47  ? 39.27000 34.23900 24.90500  1.000 80.49000  ?  47   PHE N    CB  1 
ATOM   5881 C CG  . PHE D 4 47  ? 40.70900 34.22300 25.33900  1.000 76.77000  ?  47   PHE N    CG  1 
ATOM   5882 C CD1 . PHE D 4 47  ? 41.33800 35.38000 25.75400  1.000 76.14000  ?  47   PHE N    CD1 1 
ATOM   5883 C CD2 . PHE D 4 47  ? 41.42100 33.04400 25.35300  1.000 73.29000  ?  47   PHE N    CD2 1 
ATOM   5884 C CE1 . PHE D 4 47  ? 42.65700 35.35700 26.16500  1.000 75.37000  ?  47   PHE N    CE1 1 
ATOM   5885 C CE2 . PHE D 4 47  ? 42.73500 33.02400 25.75100  1.000 77.75000  ?  47   PHE N    CE2 1 
ATOM   5886 C CZ  . PHE D 4 47  ? 43.35300 34.18100 26.16500  1.000 75.45000  ?  47   PHE N    CZ  1 
ATOM   5887 N N   . VAL D 4 48  ? 41.04200 35.20800 22.21400  1.000 79.50000  ?  48   VAL N    N   1 
ATOM   5888 C CA  . VAL D 4 48  ? 42.17800 34.78900 21.40400  1.000 83.45000  ?  48   VAL N    CA  1 
ATOM   5889 C C   . VAL D 4 48  ? 43.47300 34.75800 22.21500  1.000 82.92000  ?  48   VAL N    C   1 
ATOM   5890 O O   . VAL D 4 48  ? 44.18700 33.75400 22.20200  1.000 85.81000  ?  48   VAL N    O   1 
ATOM   5891 C CB  . VAL D 4 48  ? 42.33100 35.64800 20.12600  1.000 87.51000  ?  48   VAL N    CB  1 
ATOM   5892 C CG1 . VAL D 4 48  ? 41.28200 35.28200 19.10000  1.000 85.29000  ?  48   VAL N    CG1 1 
ATOM   5893 C CG2 . VAL D 4 48  ? 42.21200 37.03700 20.41800  1.000 87.46000  ?  48   VAL N    CG2 1 
ATOM   5894 N N   . ALA D 4 49  ? 43.78500 35.83100 22.94700  1.000 85.20000  ?  49   ALA N    N   1 
ATOM   5895 C CA  . ALA D 4 49  ? 45.03200 35.81400 23.71300  1.000 86.93000  ?  49   ALA N    CA  1 
ATOM   5896 C C   . ALA D 4 49  ? 45.09300 36.95700 24.74400  1.000 92.52000  ?  49   ALA N    C   1 
ATOM   5897 O O   . ALA D 4 49  ? 44.31400 37.91700 24.68500  1.000 85.17000  ?  49   ALA N    O   1 
ATOM   5898 C CB  . ALA D 4 49  ? 46.21700 35.84100 22.75400  1.000 83.93000  ?  49   ALA N    CB  1 
ATOM   5899 N N   . ARG D 4 50  ? 46.01900 36.82000 25.71000  1.000 96.79000  ?  50   ARG N    N   1 
ATOM   5900 C CA  . ARG D 4 50  ? 46.17600 37.75400 26.82900  1.000 89.79000  ?  50   ARG N    CA  1 
ATOM   5901 C C   . ARG D 4 50  ? 47.63900 37.84100 27.24900  1.000 92.53000  ?  50   ARG N    C   1 
ATOM   5902 O O   . ARG D 4 50  ? 48.42900 36.93500 26.97100  1.000 94.73000  ?  50   ARG N    O   1 
ATOM   5903 C CB  . ARG D 4 50  ? 45.35700 37.31300 28.04500  1.000 93.79000  ?  50   ARG N    CB  1 
ATOM   5904 C CG  . ARG D 4 50  ? 46.10800 36.36700 29.01100  1.000 92.76000  ?  50   ARG N    CG  1 
ATOM   5905 C CD  . ARG D 4 50  ? 45.43600 36.32000 30.36500  1.000 83.86000  ?  50   ARG N    CD  1 
ATOM   5906 N NE  . ARG D 4 50  ? 44.04200 35.92000 30.24400  1.000 69.19000  ?  50   ARG N    NE  1 
ATOM   5907 C CZ  . ARG D 4 50  ? 43.65400 34.66600 30.09400  1.000 72.06000  ?  50   ARG N    CZ  1 
ATOM   5908 N NH1 . ARG D 4 50  ? 44.52500 33.67200 30.09200  1.000 74.66000  ?  50   ARG N    NH1 1 
ATOM   5909 N NH2 . ARG D 4 50  ? 42.36000 34.40000 29.95700  1.000 69.61000  ?  50   ARG N    NH2 1 
ATOM   5910 N N   . ILE D 4 51  ? 47.99400 38.93000 27.95200  1.000 98.18000  ?  51   ILE N    N   1 
ATOM   5911 C CA  . ILE D 4 51  ? 49.27600 39.02900 28.67300  1.000 104.69000 ?  51   ILE N    CA  1 
ATOM   5912 C C   . ILE D 4 51  ? 48.84500 39.46800 30.06900  1.000 108.62000 ?  51   ILE N    C   1 
ATOM   5913 O O   . ILE D 4 51  ? 48.54000 40.64600 30.29300  1.000 103.86000 ?  51   ILE N    O   1 
ATOM   5914 C CB  . ILE D 4 51  ? 50.29000 39.99300 28.04700  1.000 104.71000 ?  51   ILE N    CB  1 
ATOM   5915 C CG1 . ILE D 4 51  ? 50.49900 39.80900 26.56700  1.000 104.74000 ?  51   ILE N    CG1 1 
ATOM   5916 C CG2 . ILE D 4 51  ? 51.62600 39.84500 28.73700  1.000 113.57000 ?  51   ILE N    CG2 1 
ATOM   5917 C CD1 . ILE D 4 51  ? 49.40000 40.50600 25.83600  1.000 107.76000 ?  51   ILE N    CD1 1 
ATOM   5918 N N   . ASN D 4 52  ? 48.82900 38.54400 31.00600  1.000 114.58000 ?  52   ASN N    N   1 
ATOM   5919 C CA  . ASN D 4 52  ? 49.00600 38.93600 32.39400  1.000 119.71000 ?  52   ASN N    CA  1 
ATOM   5920 C C   . ASN D 4 52  ? 50.48200 39.30700 32.54900  1.000 125.59000 ?  52   ASN N    C   1 
ATOM   5921 O O   . ASN D 4 52  ? 51.34800 38.44000 32.34500  1.000 125.59000 ?  52   ASN N    O   1 
ATOM   5922 C CB  . ASN D 4 52  ? 48.56000 37.77000 33.28500  1.000 118.49000 ?  52   ASN N    CB  1 
ATOM   5923 C CG  . ASN D 4 52  ? 48.83300 36.38700 32.64700  1.000 118.97000 ?  52   ASN N    CG  1 
ATOM   5924 O OD1 . ASN D 4 52  ? 49.59700 36.27100 31.68400  1.000 112.64000 ?  52   ASN N    OD1 1 
ATOM   5925 N ND2 . ASN D 4 52  ? 48.16900 35.34600 33.16400  1.000 115.05000 ?  52   ASN N    ND2 1 
ATOM   5926 N N   . PRO D 4 53  ? 50.82900 40.58900 32.79600  1.000 130.05000 ?  53   PRO N    N   1 
ATOM   5927 C CA  . PRO D 4 53  ? 52.23300 40.98200 32.84700  1.000 132.52000 ?  53   PRO N    CA  1 
ATOM   5928 C C   . PRO D 4 53  ? 52.97700 40.01700 33.77400  1.000 139.40000 ?  53   PRO N    C   1 
ATOM   5929 O O   . PRO D 4 53  ? 54.19100 39.97200 33.71900  1.000 140.59000 ?  53   PRO N    O   1 
ATOM   5930 C CB  . PRO D 4 53  ? 52.17300 42.39200 33.44500  1.000 123.68000 ?  53   PRO N    CB  1 
ATOM   5931 C CG  . PRO D 4 53  ? 50.83100 42.92200 33.00200  1.000 113.78000 ?  53   PRO N    CG  1 
ATOM   5932 C CD  . PRO D 4 53  ? 49.92000 41.71400 33.05000  1.000 120.79000 ?  53   PRO N    CD  1 
ATOM   5933 N N   . THR D 4 54  ? 52.23200 39.25600 34.57700  1.000 136.59000 ?  54   THR N    N   1 
ATOM   5934 C CA  . THR D 4 54  ? 52.87000 38.35400 35.56900  1.000 136.51000 ?  54   THR N    CA  1 
ATOM   5935 C C   . THR D 4 54  ? 53.28800 37.03800 34.91200  1.000 135.65000 ?  54   THR N    C   1 
ATOM   5936 O O   . THR D 4 54  ? 52.54500 36.04900 35.05400  1.000 131.66000 ?  54   THR N    O   1 
ATOM   5937 C CB  . THR D 4 54  ? 51.92100 38.08700 36.74100  1.000 134.38000 ?  54   THR N    CB  1 
ATOM   5938 O OG1 . THR D 4 54  ? 52.41300 36.95500 37.45900  1.000 129.04000 ?  54   THR N    OG1 1 
ATOM   5939 C CG2 . THR D 4 54  ? 50.49600 37.83400 36.29900  1.000 129.83000 ?  54   THR N    CG2 1 
ATOM   5940 N N   . GLY D 4 55  ? 54.43400 37.02400 34.23200  1.000 134.48000 ?  55   GLY N    N   1 
ATOM   5941 C CA  . GLY D 4 55  ? 54.92500 35.75400 33.66800  1.000 133.78000 ?  55   GLY N    CA  1 
ATOM   5942 C C   . GLY D 4 55  ? 54.99600 35.76700 32.15400  1.000 136.63000 ?  55   GLY N    C   1 
ATOM   5943 O O   . GLY D 4 55  ? 56.10300 35.98300 31.62900  1.000 140.68000 ?  55   GLY N    O   1 
ATOM   5944 N N   . SER D 4 56  ? 53.87200 35.53600 31.46800  1.000 126.59000 ?  56   SER N    N   1 
ATOM   5945 C CA  . SER D 4 56  ? 53.94300 35.43100 30.01400  1.000 123.73000 ?  56   SER N    CA  1 
ATOM   5946 C C   . SER D 4 56  ? 52.50800 35.50700 29.48500  1.000 120.77000 ?  56   SER N    C   1 
ATOM   5947 O O   . SER D 4 56  ? 51.59900 35.93500 30.20700  1.000 116.41000 ?  56   SER N    O   1 
ATOM   5948 C CB  . SER D 4 56  ? 54.41100 34.01400 29.62800  1.000 131.52000 ?  56   SER N    CB  1 
ATOM   5949 O OG  . SER D 4 56  ? 54.83000 33.91300 28.26700  1.000 131.94000 ?  56   SER N    OG  1 
ATOM   5950 N N   . ALA D 4 57  ? 52.30500 35.10500 28.22000  1.000 118.87000 ?  57   ALA N    N   1 
ATOM   5951 C CA  . ALA D 4 57  ? 51.01200 35.16700 27.54500  1.000 103.99000 ?  57   ALA N    CA  1 
ATOM   5952 C C   . ALA D 4 57  ? 50.39300 33.83300 27.14200  1.000 99.10000  ?  57   ALA N    C   1 
ATOM   5953 O O   . ALA D 4 57  ? 51.09900 32.86600 26.85500  1.000 97.33000  ?  57   ALA N    O   1 
ATOM   5954 C CB  . ALA D 4 57  ? 51.30100 35.99100 26.29500  1.000 95.86000  ?  57   ALA N    CB  1 
ATOM   5955 N N   . ASN D 4 58  ? 49.06700 33.79600 27.12400  1.000 100.13000 ?  58   ASN N    N   1 
ATOM   5956 C CA  . ASN D 4 58  ? 48.29100 32.60700 26.80500  1.000 98.16000  ?  58   ASN N    CA  1 
ATOM   5957 C C   . ASN D 4 58  ? 47.55300 32.87500 25.50200  1.000 100.87000 ?  58   ASN N    C   1 
ATOM   5958 O O   . ASN D 4 58  ? 47.14100 34.01400 25.25300  1.000 98.55000  ?  58   ASN N    O   1 
ATOM   5959 C CB  . ASN D 4 58  ? 47.27200 32.30100 27.90800  1.000 97.73000  ?  58   ASN N    CB  1 
ATOM   5960 C CG  . ASN D 4 58  ? 47.87400 32.38100 29.30300  1.000 102.47000 ?  58   ASN N    CG  1 
ATOM   5961 O OD1 . ASN D 4 58  ? 47.53000 33.27700 30.09900  1.000 95.60000  ?  58   ASN N    OD1 1 
ATOM   5962 N ND2 . ASN D 4 58  ? 48.79400 31.46200 29.60200  1.000 105.68000 ?  58   ASN N    ND2 1 
ATOM   5963 N N   . TYR D 4 59  ? 47.38300 31.83600 24.67300  1.000 96.76000  ?  59   TYR N    N   1 
ATOM   5964 C CA  . TYR D 4 59  ? 46.70200 31.95400 23.38900  1.000 88.56000  ?  59   TYR N    CA  1 
ATOM   5965 C C   . TYR D 4 59  ? 45.50600 31.01100 23.34900  1.000 89.38000  ?  59   TYR N    C   1 
ATOM   5966 O O   . TYR D 4 59  ? 45.44600 30.03000 24.09300  1.000 88.58000  ?  59   TYR N    O   1 
ATOM   5967 C CB  . TYR D 4 59  ? 47.65800 31.65300 22.22900  1.000 91.16000  ?  59   TYR N    CB  1 
ATOM   5968 C CG  . TYR D 4 59  ? 48.82700 32.60400 22.14100  1.000 90.88000  ?  59   TYR N    CG  1 
ATOM   5969 C CD1 . TYR D 4 59  ? 48.68000 33.85100 21.55200  1.000 93.61000  ?  59   TYR N    CD1 1 
ATOM   5970 C CD2 . TYR D 4 59  ? 50.06700 32.27200 22.67300  1.000 87.59000  ?  59   TYR N    CD2 1 
ATOM   5971 C CE1 . TYR D 4 59  ? 49.73500 34.74100 21.47400  1.000 93.95000  ?  59   TYR N    CE1 1 
ATOM   5972 C CE2 . TYR D 4 59  ? 51.13400 33.15300 22.59900  1.000 88.21000  ?  59   TYR N    CE2 1 
ATOM   5973 C CZ  . TYR D 4 59  ? 50.95600 34.38800 21.99600  1.000 96.13000  ?  59   TYR N    CZ  1 
ATOM   5974 O OH  . TYR D 4 59  ? 51.99300 35.28700 21.91100  1.000 99.66000  ?  59   TYR N    OH  1 
ATOM   5975 N N   . ALA D 4 60  ? 44.54100 31.32500 22.48200  1.000 91.05000  ?  60   ALA N    N   1 
ATOM   5976 C CA  . ALA D 4 60  ? 43.43600 30.40400 22.25200  1.000 89.26000  ?  60   ALA N    CA  1 
ATOM   5977 C C   . ALA D 4 60  ? 43.92600 29.18800 21.47600  1.000 100.27000 ?  60   ALA N    C   1 
ATOM   5978 O O   . ALA D 4 60  ? 44.92800 29.24000 20.74500  1.000 101.39000 ?  60   ALA N    O   1 
ATOM   5979 C CB  . ALA D 4 60  ? 42.29900 31.08000 21.48900  1.000 78.93000  ?  60   ALA N    CB  1 
ATOM   5980 N N   . ASP D 4 61  ? 43.19200 28.08000 21.62900  1.000 102.04000 ?  61   ASP N    N   1 
ATOM   5981 C CA  . ASP D 4 61  ? 43.62400 26.82800 21.00300  1.000 111.90000 ?  61   ASP N    CA  1 
ATOM   5982 C C   . ASP D 4 61  ? 43.63800 26.92100 19.47700  1.000 106.87000 ?  61   ASP N    C   1 
ATOM   5983 O O   . ASP D 4 61  ? 44.53200 26.36500 18.82600  1.000 105.44000 ?  61   ASP N    O   1 
ATOM   5984 C CB  . ASP D 4 61  ? 42.74400 25.67800 21.47900  1.000 106.70000 ?  61   ASP N    CB  1 
ATOM   5985 C CG  . ASP D 4 61  ? 43.27300 25.05900 22.75800  1.000 118.57000 ?  61   ASP N    CG  1 
ATOM   5986 O OD1 . ASP D 4 61  ? 44.51900 24.99100 22.90300  1.000 119.34000 ?  61   ASP N    OD1 1 
ATOM   5987 O OD2 . ASP D 4 61  ? 42.45600 24.66300 23.62300  1.000 119.37000 ?  61   ASP N    OD2 1 
ATOM   5988 N N   . SER D 4 62  ? 42.67500 27.64000 18.89900  1.000 102.77000 ?  62   SER N    N   1 
ATOM   5989 C CA  . SER D 4 62  ? 42.64300 27.86000 17.46100  1.000 100.99000 ?  62   SER N    CA  1 
ATOM   5990 C C   . SER D 4 62  ? 43.95300 28.39500 16.91500  1.000 103.66000 ?  62   SER N    C   1 
ATOM   5991 O O   . SER D 4 62  ? 44.29700 28.11800 15.76100  1.000 114.73000 ?  62   SER N    O   1 
ATOM   5992 C CB  . SER D 4 62  ? 41.52900 28.84700 17.10500  1.000 104.57000 ?  62   SER N    CB  1 
ATOM   5993 O OG  . SER D 4 62  ? 40.25000 28.34500 17.45700  1.000 114.50000 ?  62   SER N    OG  1 
ATOM   5994 N N   . VAL D 4 63  ? 44.69400 29.16700 17.70200  1.000 100.10000 ?  63   VAL N    N   1 
ATOM   5995 C CA  . VAL D 4 63  ? 45.66300 30.06600 17.08800  1.000 103.68000 ?  63   VAL N    CA  1 
ATOM   5996 C C   . VAL D 4 63  ? 47.08000 29.88200 17.62300  1.000 109.89000 ?  63   VAL N    C   1 
ATOM   5997 O O   . VAL D 4 63  ? 47.89200 30.81600 17.55300  1.000 107.71000 ?  63   VAL N    O   1 
ATOM   5998 C CB  . VAL D 4 63  ? 45.18600 31.51000 17.28500  1.000 98.81000  ?  63   VAL N    CB  1 
ATOM   5999 C CG1 . VAL D 4 63  ? 43.80200 31.65400 16.72600  1.000 100.45000 ?  63   VAL N    CG1 1 
ATOM   6000 C CG2 . VAL D 4 63  ? 45.16900 31.86000 18.74900  1.000 98.84000  ?  63   VAL N    CG2 1 
ATOM   6001 N N   . ARG D 4 64  ? 47.40200 28.65900 18.07800  1.000 108.59000 ?  64   ARG N    N   1 
ATOM   6002 C CA  . ARG D 4 64  ? 48.55600 28.42200 18.95000  1.000 110.20000 ?  64   ARG N    CA  1 
ATOM   6003 C C   . ARG D 4 64  ? 49.83700 29.07900 18.41100  1.000 111.13000 ?  64   ARG N    C   1 
ATOM   6004 O O   . ARG D 4 64  ? 50.40100 29.98600 19.03900  1.000 102.92000 ?  64   ARG N    O   1 
ATOM   6005 C CB  . ARG D 4 64  ? 48.75100 26.89800 19.17800  1.000 118.86000 ?  64   ARG N    CB  1 
ATOM   6006 C CG  . ARG D 4 64  ? 49.75200 26.15900 18.22900  1.000 120.85000 ?  64   ARG N    CG  1 
ATOM   6007 C CD  . ARG D 4 64  ? 50.30000 24.81100 18.68800  1.000 121.86000 ?  64   ARG N    CD  1 
ATOM   6008 N NE  . ARG D 4 64  ? 49.39200 23.69800 18.44600  1.000 132.05000 ?  64   ARG N    NE  1 
ATOM   6009 C CZ  . ARG D 4 64  ? 49.55700 22.47400 18.93300  1.000 136.82000 ?  64   ARG N    CZ  1 
ATOM   6010 N NH1 . ARG D 4 64  ? 50.54100 22.18900 19.77300  1.000 132.78000 ?  64   ARG N    NH1 1 
ATOM   6011 N NH2 . ARG D 4 64  ? 48.71600 21.51100 18.56500  1.000 136.90000 ?  64   ARG N    NH2 1 
ATOM   6012 N N   . GLY D 4 65  ? 50.28500 28.66900 17.22400  1.000 109.46000 ?  65   GLY N    N   1 
ATOM   6013 C CA  . GLY D 4 65  ? 51.64000 28.94700 16.79300  1.000 112.86000 ?  65   GLY N    CA  1 
ATOM   6014 C C   . GLY D 4 65  ? 51.63300 29.96200 15.68000  1.000 113.83000 ?  65   GLY N    C   1 
ATOM   6015 O O   . GLY D 4 65  ? 52.67600 30.33700 15.13200  1.000 111.82000 ?  65   GLY N    O   1 
ATOM   6016 N N   . ARG D 4 66  ? 50.43700 30.46800 15.37600  1.000 111.64000 ?  66   ARG N    N   1 
ATOM   6017 C CA  . ARG D 4 66  ? 50.29300 31.44400 14.26800  1.000 107.62000 ?  66   ARG N    CA  1 
ATOM   6018 C C   . ARG D 4 66  ? 50.26200 32.86600 14.82900  1.000 108.60000 ?  66   ARG N    C   1 
ATOM   6019 O O   . ARG D 4 66  ? 50.75500 33.77200 14.13700  1.000 107.65000 ?  66   ARG N    O   1 
ATOM   6020 C CB  . ARG D 4 66  ? 48.99900 31.15200 13.50700  1.000 103.85000 ?  66   ARG N    CB  1 
ATOM   6021 C CG  . ARG D 4 66  ? 48.59500 29.68500 13.51400  1.000 101.00000 ?  66   ARG N    CG  1 
ATOM   6022 C CD  . ARG D 4 66  ? 47.48900 29.42400 12.51400  1.000 94.63000  ?  66   ARG N    CD  1 
ATOM   6023 N NE  . ARG D 4 66  ? 46.42500 30.40800 12.62200  1.000 102.48000 ?  66   ARG N    NE  1 
ATOM   6024 C CZ  . ARG D 4 66  ? 45.16400 30.11700 12.91100  1.000 106.41000 ?  66   ARG N    CZ  1 
ATOM   6025 N NH1 . ARG D 4 66  ? 44.80400 28.86100 13.11100  1.000 106.65000 ?  66   ARG N    NH1 1 
ATOM   6026 N NH2 . ARG D 4 66  ? 44.26700 31.08100 13.00300  1.000 104.66000 ?  66   ARG N    NH2 1 
ATOM   6027 N N   . PHE D 4 67  ? 49.71400 33.05300 16.03100  1.000 108.53000 ?  67   PHE N    N   1 
ATOM   6028 C CA  . PHE D 4 67  ? 49.56600 34.39800 16.58400  1.000 107.92000 ?  67   PHE N    CA  1 
ATOM   6029 C C   . PHE D 4 67  ? 50.54100 34.64000 17.73800  1.000 105.06000 ?  67   PHE N    C   1 
ATOM   6030 O O   . PHE D 4 67  ? 51.09000 33.70200 18.33100  1.000 101.84000 ?  67   PHE N    O   1 
ATOM   6031 C CB  . PHE D 4 67  ? 48.12600 34.65100 17.06300  1.000 103.23000 ?  67   PHE N    CB  1 
ATOM   6032 C CG  . PHE D 4 67  ? 47.10000 34.61900 15.96300  1.000 108.31000 ?  67   PHE N    CG  1 
ATOM   6033 C CD1 . PHE D 4 67  ? 47.48700 34.60900 14.62100  1.000 115.73000 ?  67   PHE N    CD1 1 
ATOM   6034 C CD2 . PHE D 4 67  ? 45.75200 34.59200 16.25700  1.000 103.33000 ?  67   PHE N    CD2 1 
ATOM   6035 C CE1 . PHE D 4 67  ? 46.54700 34.56200 13.59800  1.000 108.82000 ?  67   PHE N    CE1 1 
ATOM   6036 C CE2 . PHE D 4 67  ? 44.80500 34.53900 15.23200  1.000 106.17000 ?  67   PHE N    CE2 1 
ATOM   6037 C CZ  . PHE D 4 67  ? 45.20500 34.52100 13.91000  1.000 105.34000 ?  67   PHE N    CZ  1 
ATOM   6038 N N   . THR D 4 68  ? 50.78700 35.92200 18.02700  1.000 102.61000 ?  68   THR N    N   1 
ATOM   6039 C CA  . THR D 4 68  ? 51.74200 36.29700 19.10100  1.000 100.34000 ?  68   THR N    CA  1 
ATOM   6040 C C   . THR D 4 68  ? 51.37700 37.68400 19.63800  1.000 104.91000 ?  68   THR N    C   1 
ATOM   6041 O O   . THR D 4 68  ? 51.12700 38.57700 18.81000  1.000 100.61000 ?  68   THR N    O   1 
ATOM   6042 C CB  . THR D 4 68  ? 53.17600 36.28600 18.56700  1.000 103.17000 ?  68   THR N    CB  1 
ATOM   6043 O OG1 . THR D 4 68  ? 53.45300 34.97800 18.06900  1.000 108.41000 ?  68   THR N    OG1 1 
ATOM   6044 C CG2 . THR D 4 68  ? 54.19600 36.66300 19.61900  1.000 100.59000 ?  68   THR N    CG2 1 
ATOM   6045 N N   . ILE D 4 69  ? 51.36300 37.86000 20.95800  1.000 104.57000 ?  69   ILE N    N   1 
ATOM   6046 C CA  . ILE D 4 69  ? 50.94700 39.16500 21.54700  1.000 101.61000 ?  69   ILE N    CA  1 
ATOM   6047 C C   . ILE D 4 69  ? 52.18400 39.92100 22.03500  1.000 97.59000  ?  69   ILE N    C   1 
ATOM   6048 O O   . ILE D 4 69  ? 53.24500 39.29000 22.15300  1.000 94.84000  ?  69   ILE N    O   1 
ATOM   6049 C CB  . ILE D 4 69  ? 49.94300 38.93500 22.68900  1.000 97.01000  ?  69   ILE N    CB  1 
ATOM   6050 C CG1 . ILE D 4 69  ? 50.31200 37.69800 23.50600  1.000 98.29000  ?  69   ILE N    CG1 1 
ATOM   6051 C CG2 . ILE D 4 69  ? 48.52500 38.84400 22.15300  1.000 104.94000 ?  69   ILE N    CG2 1 
ATOM   6052 C CD1 . ILE D 4 69  ? 51.76400 37.65600 23.91100  1.000 97.86000  ?  69   ILE N    CD1 1 
ATOM   6053 N N   . SER D 4 70  ? 52.05300 41.22500 22.28100  1.000 97.58000  ?  70   SER N    N   1 
ATOM   6054 C CA  . SER D 4 70  ? 53.17200 42.01400 22.86100  1.000 104.14000 ?  70   SER N    CA  1 
ATOM   6055 C C   . SER D 4 70  ? 52.71900 43.43800 23.18900  1.000 103.79000 ?  70   SER N    C   1 
ATOM   6056 O O   . SER D 4 70  ? 51.65900 43.84800 22.68800  1.000 103.25000 ?  70   SER N    O   1 
ATOM   6057 C CB  . SER D 4 70  ? 54.34600 42.03400 21.93400  1.000 114.26000 ?  70   SER N    CB  1 
ATOM   6058 O OG  . SER D 4 70  ? 55.39500 42.82200 22.47700  1.000 121.51000 ?  70   SER N    OG  1 
ATOM   6059 N N   . LYS D 4 71  ? 53.56800 44.16900 23.90600  1.000 103.97000 ?  71   LYS N    N   1 
ATOM   6060 C CA  . LYS D 4 71  ? 53.26100 45.57300 24.25700  1.000 115.86000 ?  71   LYS N    CA  1 
ATOM   6061 C C   . LYS D 4 71  ? 54.57300 46.35300 24.29200  1.000 118.69000 ?  71   LYS N    C   1 
ATOM   6062 O O   . LYS D 4 71  ? 55.54000 45.84100 24.87800  1.000 120.14000 ?  71   LYS N    O   1 
ATOM   6063 C CB  . LYS D 4 71  ? 52.60300 45.61900 25.63600  1.000 117.72000 ?  71   LYS N    CB  1 
ATOM   6064 C CG  . LYS D 4 71  ? 53.42400 45.00400 26.76200  1.000 110.34000 ?  71   LYS N    CG  1 
ATOM   6065 C CD  . LYS D 4 71  ? 52.63700 44.76600 28.03100  1.000 113.52000 ?  71   LYS N    CD  1 
ATOM   6066 C CE  . LYS D 4 71  ? 51.90500 45.99800 28.51600  1.000 126.35000 ?  71   LYS N    CE  1 
ATOM   6067 N NZ  . LYS D 4 71  ? 51.32200 45.79100 29.86300  1.000 123.15000 ?  71   LYS N    NZ  1 
ATOM   6068 N N   . ASP D 4 72  ? 54.61900 47.52300 23.66200  1.000 120.14000 ?  72   ASP N    N   1 
ATOM   6069 C CA  . ASP D 4 72  ? 55.83500 48.36400 23.78700  1.000 129.40000 ?  72   ASP N    CA  1 
ATOM   6070 C C   . ASP D 4 72  ? 55.58300 49.35700 24.91900  1.000 132.50000 ?  72   ASP N    C   1 
ATOM   6071 O O   . ASP D 4 72  ? 55.29700 50.51900 24.61900  1.000 134.64000 ?  72   ASP N    O   1 
ATOM   6072 C CB  . ASP D 4 72  ? 56.18000 49.08900 22.48800  1.000 131.91000 ?  72   ASP N    CB  1 
ATOM   6073 C CG  . ASP D 4 72  ? 57.37800 50.01000 22.63500  1.000 137.38000 ?  72   ASP N    CG  1 
ATOM   6074 O OD1 . ASP D 4 72  ? 58.46400 49.50600 22.98200  1.000 139.05000 ?  72   ASP N    OD1 1 
ATOM   6075 O OD2 . ASP D 4 72  ? 57.21200 51.22300 22.41600  1.000 134.71000 ?  72   ASP N    OD2 1 
ATOM   6076 N N   . ASN D 4 73  ? 55.70000 48.91500 26.16800  1.000 129.33000 ?  73   ASN N    N   1 
ATOM   6077 C CA  . ASN D 4 73  ? 55.36700 49.80800 27.30600  1.000 130.81000 ?  73   ASN N    CA  1 
ATOM   6078 C C   . ASN D 4 73  ? 55.84900 51.23200 27.01900  1.000 130.22000 ?  73   ASN N    C   1 
ATOM   6079 O O   . ASN D 4 73  ? 55.13700 52.17700 27.39900  1.000 129.18000 ?  73   ASN N    O   1 
ATOM   6080 C CB  . ASN D 4 73  ? 55.98500 49.29800 28.60700  1.000 130.54000 ?  73   ASN N    CB  1 
ATOM   6081 C CG  . ASN D 4 73  ? 55.42000 47.96300 29.04000  1.000 123.96000 ?  73   ASN N    CG  1 
ATOM   6082 O OD1 . ASN D 4 73  ? 56.14500 46.97600 29.13300  1.000 126.60000 ?  73   ASN N    OD1 1 
ATOM   6083 N ND2 . ASN D 4 73  ? 54.12500 47.92300 29.30100  1.000 113.80000 ?  73   ASN N    ND2 1 
ATOM   6084 N N   . SER D 4 74  ? 57.00300 51.37300 26.36100  1.000 133.03000 ?  74   SER N    N   1 
ATOM   6085 C CA  . SER D 4 74  ? 57.50700 52.71100 25.95800  1.000 132.09000 ?  74   SER N    CA  1 
ATOM   6086 C C   . SER D 4 74  ? 56.40900 53.45900 25.20000  1.000 130.89000 ?  74   SER N    C   1 
ATOM   6087 O O   . SER D 4 74  ? 56.13800 54.61900 25.55100  1.000 128.03000 ?  74   SER N    O   1 
ATOM   6088 C CB  . SER D 4 74  ? 58.75100 52.58800 25.13100  1.000 132.00000 ?  74   SER N    CB  1 
ATOM   6089 O OG  . SER D 4 74  ? 59.75900 51.88500 25.84100  1.000 134.54000 ?  74   SER N    OG  1 
ATOM   6090 N N   . LYS D 4 75  ? 55.82500 52.84200 24.17600  1.000 133.91000 ?  75   LYS N    N   1 
ATOM   6091 C CA  . LYS D 4 75  ? 54.68100 53.47500 23.47400  1.000 131.92000 ?  75   LYS N    CA  1 
ATOM   6092 C C   . LYS D 4 75  ? 53.41100 52.76200 23.92800  1.000 128.93000 ?  75   LYS N    C   1 
ATOM   6093 O O   . LYS D 4 75  ? 53.31800 51.56900 23.67000  1.000 128.46000 ?  75   LYS N    O   1 
ATOM   6094 C CB  . LYS D 4 75  ? 54.83200 53.34400 21.95800  1.000 132.03000 ?  75   LYS N    CB  1 
ATOM   6095 C CG  . LYS D 4 75  ? 56.08900 53.96700 21.37000  1.000 135.02000 ?  75   LYS N    CG  1 
ATOM   6096 C CD  . LYS D 4 75  ? 56.46700 53.37000 20.03200  1.000 134.56000 ?  75   LYS N    CD  1 
ATOM   6097 C CE  . LYS D 4 75  ? 55.55900 52.23200 19.61700  1.000 132.33000 ?  75   LYS N    CE  1 
ATOM   6098 N NZ  . LYS D 4 75  ? 56.25700 50.92700 19.67400  1.000 133.18000 ?  75   LYS N    NZ  1 
ATOM   6099 N N   . LYS D 4 76  ? 52.49700 53.47200 24.58600  1.000 123.59000 ?  76   LYS N    N   1 
ATOM   6100 C CA  . LYS D 4 76  ? 51.26000 52.84800 25.12200  1.000 120.58000 ?  76   LYS N    CA  1 
ATOM   6101 C C   . LYS D 4 76  ? 50.56000 52.05100 24.02100  1.000 118.28000 ?  76   LYS N    C   1 
ATOM   6102 O O   . LYS D 4 76  ? 49.46600 52.46600 23.61000  1.000 117.48000 ?  76   LYS N    O   1 
ATOM   6103 C CB  . LYS D 4 76  ? 50.32600 53.93900 25.65100  1.000 121.56000 ?  76   LYS N    CB  1 
ATOM   6104 C CG  . LYS D 4 76  ? 50.71200 54.54300 26.99500  1.000 115.00000 ?  76   LYS N    CG  1 
ATOM   6105 C CD  . LYS D 4 76  ? 50.01700 55.85900 27.27500  1.000 115.39000 ?  76   LYS N    CD  1 
ATOM   6106 C CE  . LYS D 4 76  ? 48.96800 55.76700 28.36300  1.000 116.86000 ?  76   LYS N    CE  1 
ATOM   6107 N NZ  . LYS D 4 76  ? 49.57300 55.77100 29.71500  1.000 110.48000 ?  76   LYS N    NZ  1 
ATOM   6108 N N   . THR D 4 77  ? 51.14800 50.93600 23.58900  1.000 116.44000 ?  77   THR N    N   1 
ATOM   6109 C CA  . THR D 4 77  ? 50.56800 50.17200 22.49400  1.000 111.89000 ?  77   THR N    CA  1 
ATOM   6110 C C   . THR D 4 77  ? 50.58600 48.67100 22.75600  1.000 107.40000 ?  77   THR N    C   1 
ATOM   6111 O O   . THR D 4 77  ? 51.45700 48.15200 23.44600  1.000 108.62000 ?  77   THR N    O   1 
ATOM   6112 C CB  . THR D 4 77  ? 51.30300 50.44800 21.17600  1.000 118.51000 ?  77   THR N    CB  1 
ATOM   6113 O OG1 . THR D 4 77  ? 50.65500 49.73400 20.12100  1.000 117.66000 ?  77   THR N    OG1 1 
ATOM   6114 C CG2 . THR D 4 77  ? 52.75000 49.98500 21.25400  1.000 121.77000 ?  77   THR N    CG2 1 
ATOM   6115 N N   . LEU D 4 78  ? 49.62100 47.97600 22.16200  1.000 106.78000 ?  78   LEU N    N   1 
ATOM   6116 C CA  . LEU D 4 78  ? 49.46200 46.53100 22.28200  1.000 103.60000 ?  78   LEU N    CA  1 
ATOM   6117 C C   . LEU D 4 78  ? 49.17900 45.94900 20.91400  1.000 104.52000 ?  78   LEU N    C   1 
ATOM   6118 O O   . LEU D 4 78  ? 48.27200 46.42300 20.22500  1.000 102.71000 ?  78   LEU N    O   1 
ATOM   6119 C CB  . LEU D 4 78  ? 48.31600 46.16100 23.23200  1.000 101.07000 ?  78   LEU N    CB  1 
ATOM   6120 C CG  . LEU D 4 78  ? 47.91400 44.67600 23.21400  1.000 101.00000 ?  78   LEU N    CG  1 
ATOM   6121 C CD1 . LEU D 4 78  ? 48.75700 43.76500 24.08100  1.000 103.82000 ?  78   LEU N    CD1 1 
ATOM   6122 C CD2 . LEU D 4 78  ? 46.42900 44.52700 23.55600  1.000 91.62000  ?  78   LEU N    CD2 1 
ATOM   6123 N N   . TYR D 4 79  ? 49.92900 44.90900 20.54300  1.000 104.39000 ?  79   TYR N    N   1 
ATOM   6124 C CA  . TYR D 4 79  ? 49.81700 44.27500 19.23400  1.000 105.19000 ?  79   TYR N    CA  1 
ATOM   6125 C C   . TYR D 4 79  ? 49.39600 42.81700 19.34500  1.000 103.60000 ?  79   TYR N    C   1 
ATOM   6126 O O   . TYR D 4 79  ? 49.84200 42.09400 20.24100  1.000 97.80000  ?  79   TYR N    O   1 
ATOM   6127 C CB  . TYR D 4 79  ? 51.13700 44.32000 18.43500  1.000 103.64000 ?  79   TYR N    CB  1 
ATOM   6128 C CG  . TYR D 4 79  ? 51.89000 45.63200 18.43000  1.000 108.07000 ?  79   TYR N    CG  1 
ATOM   6129 C CD1 . TYR D 4 79  ? 51.48500 46.69000 17.60800  1.000 107.77000 ?  79   TYR N    CD1 1 
ATOM   6130 C CD2 . TYR D 4 79  ? 53.03500 45.80000 19.19500  1.000 108.36000 ?  79   TYR N    CD2 1 
ATOM   6131 C CE1 . TYR D 4 79  ? 52.18200 47.89000 17.58100  1.000 108.50000 ?  79   TYR N    CE1 1 
ATOM   6132 C CE2 . TYR D 4 79  ? 53.73900 47.00100 19.17300  1.000 113.01000 ?  79   TYR N    CE2 1 
ATOM   6133 C CZ  . TYR D 4 79  ? 53.31000 48.03800 18.36300  1.000 111.74000 ?  79   TYR N    CZ  1 
ATOM   6134 O OH  . TYR D 4 79  ? 54.01900 49.22000 18.34000  1.000 115.31000 ?  79   TYR N    OH  1 
ATOM   6135 N N   . LEU D 4 80  ? 48.55700 42.38700 18.40500  1.000 106.42000 ?  80   LEU N    N   1 
ATOM   6136 C CA  . LEU D 4 80  ? 48.41900 40.98000 18.05500  1.000 100.03000 ?  80   LEU N    CA  1 
ATOM   6137 C C   . LEU D 4 80  ? 49.01800 40.81900 16.66700  1.000 101.97000 ?  80   LEU N    C   1 
ATOM   6138 O O   . LEU D 4 80  ? 48.55100 41.44500 15.70700  1.000 100.51000 ?  80   LEU N    O   1 
ATOM   6139 C CB  . LEU D 4 80  ? 46.96500 40.51200 18.06500  1.000 90.63000  ?  80   LEU N    CB  1 
ATOM   6140 C CG  . LEU D 4 80  ? 46.85700 39.02800 17.74200  1.000 88.85000  ?  80   LEU N    CG  1 
ATOM   6141 C CD1 . LEU D 4 80  ? 47.44500 38.28200 18.90900  1.000 93.38000  ?  80   LEU N    CD1 1 
ATOM   6142 C CD2 . LEU D 4 80  ? 45.43000 38.59000 17.48400  1.000 81.63000  ?  80   LEU N    CD2 1 
ATOM   6143 N N   . GLN D 4 81  ? 50.06800 40.01200 16.57100  1.000 105.51000 ?  81   GLN N    N   1 
ATOM   6144 C CA  . GLN D 4 81  ? 50.65100 39.65100 15.28500  1.000 109.58000 ?  81   GLN N    CA  1 
ATOM   6145 C C   . GLN D 4 81  ? 49.91900 38.43500 14.72900  1.000 108.36000 ?  81   GLN N    C   1 
ATOM   6146 O O   . GLN D 4 81  ? 49.92400 37.35500 15.33900  1.000 103.97000 ?  81   GLN N    O   1 
ATOM   6147 C CB  . GLN D 4 81  ? 52.14500 39.34700 15.41300  1.000 115.18000 ?  81   GLN N    CB  1 
ATOM   6148 C CG  . GLN D 4 81  ? 52.81700 39.17600 14.06200  1.000 111.04000 ?  81   GLN N    CG  1 
ATOM   6149 C CD  . GLN D 4 81  ? 52.65900 40.42100 13.23000  1.000 114.37000 ?  81   GLN N    CD  1 
ATOM   6150 O OE1 . GLN D 4 81  ? 53.16200 41.49600 13.59400  1.000 111.46000 ?  81   GLN N    OE1 1 
ATOM   6151 N NE2 . GLN D 4 81  ? 51.88600 40.31200 12.15000  1.000 112.99000 ?  81   GLN N    NE2 1 
ATOM   6152 N N   . MET D 4 82  ? 49.30900 38.59600 13.56900  1.000 107.50000 ?  82   MET N    N   1 
ATOM   6153 C CA  . MET D 4 82  ? 48.60300 37.49700 12.93900  1.000 109.98000 ?  82   MET N    CA  1 
ATOM   6154 C C   . MET D 4 82  ? 49.42500 37.02700 11.74600  1.000 114.39000 ?  82   MET N    C   1 
ATOM   6155 O O   . MET D 4 82  ? 49.66900 37.79900 10.81400  1.000 116.25000 ?  82   MET N    O   1 
ATOM   6156 C CB  . MET D 4 82  ? 47.20800 37.94400 12.53300  1.000 109.24000 ?  82   MET N    CB  1 
ATOM   6157 C CG  . MET D 4 82  ? 46.50300 38.65900 13.65100  1.000 103.01000 ?  82   MET N    CG  1 
ATOM   6158 S SD  . MET D 4 82  ? 44.79700 39.11500 13.27400  1.000 121.08000 ?  82   MET N    SD  1 
ATOM   6159 C CE  . MET D 4 82  ? 43.99900 37.51300 13.21400  1.000 100.97000 ?  82   MET N    CE  1 
ATOM   6160 N N   . GLY D 4 83  ? 49.88100 35.77600 11.79300  1.000 111.42000 ?  83   GLY N    N   1 
ATOM   6161 C CA  . GLY D 4 83  ? 50.64100 35.20800 10.70500  1.000 111.89000 ?  83   GLY N    CA  1 
ATOM   6162 C C   . GLY D 4 83  ? 50.07400 33.85400 10.32500  1.000 116.29000 ?  83   GLY N    C   1 
ATOM   6163 O O   . GLY D 4 83  ? 49.34400 33.22100 11.09800  1.000 116.08000 ?  83   GLY N    O   1 
ATOM   6164 N N   . SER D 4 84  ? 50.37700 33.38400 9.11300   1.000 114.73000 ?  84   SER N    N   1 
ATOM   6165 C CA  . SER D 4 84  ? 49.76800 32.11100 8.64900   1.000 113.16000 ?  84   SER N    CA  1 
ATOM   6166 C C   . SER D 4 84  ? 48.25500 32.21600 8.82000   1.000 108.31000 ?  84   SER N    C   1 
ATOM   6167 O O   . SER D 4 84  ? 47.66700 31.31500 9.43800   1.000 105.44000 ?  84   SER N    O   1 
ATOM   6168 C CB  . SER D 4 84  ? 50.31800 30.93200 9.39900   1.000 109.03000 ?  84   SER N    CB  1 
ATOM   6169 O OG  . SER D 4 84  ? 49.64300 29.74000 9.02900   1.000 102.47000 ?  84   SER N    OG  1 
ATOM   6170 N N   . LEU D 4 85  ? 47.66200 33.28400 8.29000   1.000 107.47000 ?  85   LEU N    N   1 
ATOM   6171 C CA  . LEU D 4 85  ? 46.20500 33.52000 8.45400   1.000 110.13000 ?  85   LEU N    CA  1 
ATOM   6172 C C   . LEU D 4 85  ? 45.41500 32.48600 7.65200   1.000 114.29000 ?  85   LEU N    C   1 
ATOM   6173 O O   . LEU D 4 85  ? 46.01700 31.82800 6.78900   1.000 117.69000 ?  85   LEU N    O   1 
ATOM   6174 C CB  . LEU D 4 85  ? 45.89700 34.93500 7.96300   1.000 108.33000 ?  85   LEU N    CB  1 
ATOM   6175 C CG  . LEU D 4 85  ? 46.81300 36.02200 8.52100   1.000 112.37000 ?  85   LEU N    CG  1 
ATOM   6176 C CD1 . LEU D 4 85  ? 46.26100 37.40500 8.22000   1.000 114.44000 ?  85   LEU N    CD1 1 
ATOM   6177 C CD2 . LEU D 4 85  ? 47.00200 35.83800 10.01600  1.000 113.80000 ?  85   LEU N    CD2 1 
ATOM   6178 N N   . GLN D 4 86  ? 44.11800 32.36400 7.92900   1.000 108.28000 ?  86   GLN N    N   1 
ATOM   6179 C CA  . GLN D 4 86  ? 43.25400 31.38900 7.21800   1.000 112.23000 ?  86   GLN N    CA  1 
ATOM   6180 C C   . GLN D 4 86  ? 41.91700 32.06700 6.91500   1.000 115.30000 ?  86   GLN N    C   1 
ATOM   6181 O O   . GLN D 4 86  ? 41.80200 33.27400 7.17700   1.000 110.04000 ?  86   GLN N    O   1 
ATOM   6182 C CB  . GLN D 4 86  ? 43.04600 30.14600 8.08200   1.000 117.00000 ?  86   GLN N    CB  1 
ATOM   6183 C CG  . GLN D 4 86  ? 43.79500 28.91600 7.59200   1.000 116.36000 ?  86   GLN N    CG  1 
ATOM   6184 C CD  . GLN D 4 86  ? 45.14000 28.74800 8.25600   1.000 127.51000 ?  86   GLN N    CD  1 
ATOM   6185 O OE1 . GLN D 4 86  ? 46.03000 29.58400 8.12400   1.000 126.07000 ?  86   GLN N    OE1 1 
ATOM   6186 N NE2 . GLN D 4 86  ? 45.30000 27.64900 8.97300   1.000 126.46000 ?  86   GLN N    NE2 1 
ATOM   6187 N N   . PRO D 4 87  ? 40.90900 31.36500 6.35800   1.000 121.89000 ?  87   PRO N    N   1 
ATOM   6188 C CA  . PRO D 4 87  ? 39.58100 31.95300 6.14300   1.000 118.01000 ?  87   PRO N    CA  1 
ATOM   6189 C C   . PRO D 4 87  ? 38.77800 32.06500 7.43300   1.000 122.07000 ?  87   PRO N    C   1 
ATOM   6190 O O   . PRO D 4 87  ? 37.94400 32.96600 7.58000   1.000 119.40000 ?  87   PRO N    O   1 
ATOM   6191 C CB  . PRO D 4 87  ? 38.92500 30.96700 5.17500   1.000 111.99000 ?  87   PRO N    CB  1 
ATOM   6192 C CG  . PRO D 4 87  ? 39.53200 29.64800 5.57700   1.000 113.30000 ?  87   PRO N    CG  1 
ATOM   6193 C CD  . PRO D 4 87  ? 40.97700 29.98900 5.82600   1.000 118.75000 ?  87   PRO N    CD  1 
ATOM   6194 N N   . GLU D 4 88  ? 39.03000 31.14000 8.37200   1.000 123.29000 ?  88   GLU N    N   1 
ATOM   6195 C CA  . GLU D 4 88  ? 38.16500 30.94500 9.53200   1.000 121.00000 ?  88   GLU N    CA  1 
ATOM   6196 C C   . GLU D 4 88  ? 38.28600 32.07000 10.54600  1.000 118.27000 ?  88   GLU N    C   1 
ATOM   6197 O O   . GLU D 4 88  ? 37.37400 32.26700 11.35900  1.000 118.10000 ?  88   GLU N    O   1 
ATOM   6198 C CB  . GLU D 4 88  ? 38.50900 29.62000 10.19000  1.000 123.53000 ?  88   GLU N    CB  1 
ATOM   6199 C CG  . GLU D 4 88  ? 38.85600 28.55100 9.17700   1.000 128.08000 ?  88   GLU N    CG  1 
ATOM   6200 C CD  . GLU D 4 88  ? 39.54100 27.35700 9.80900   1.000 138.73000 ?  88   GLU N    CD  1 
ATOM   6201 O OE1 . GLU D 4 88  ? 39.92600 27.44800 10.99800  1.000 138.89000 ?  88   GLU N    OE1 1 
ATOM   6202 O OE2 . GLU D 4 88  ? 39.67900 26.32200 9.12100   1.000 143.10000 -1 88   GLU N    OE2 1 
ATOM   6203 N N   . ASP D 4 89  ? 39.38100 32.81200 10.50600  1.000 111.61000 ?  89   ASP N    N   1 
ATOM   6204 C CA  . ASP D 4 89  ? 39.62200 33.91400 11.41200  1.000 106.80000 ?  89   ASP N    CA  1 
ATOM   6205 C C   . ASP D 4 89  ? 38.97200 35.20800 10.95000  1.000 107.36000 ?  89   ASP N    C   1 
ATOM   6206 O O   . ASP D 4 89  ? 39.40600 36.29700 11.34400  1.000 102.49000 ?  89   ASP N    O   1 
ATOM   6207 C CB  . ASP D 4 89  ? 41.12900 34.08700 11.57800  1.000 107.94000 ?  89   ASP N    CB  1 
ATOM   6208 C CG  . ASP D 4 89  ? 41.83300 32.75500 11.78100  1.000 113.02000 ?  89   ASP N    CG  1 
ATOM   6209 O OD1 . ASP D 4 89  ? 41.15000 31.78900 12.20000  1.000 114.36000 ?  89   ASP N    OD1 1 
ATOM   6210 O OD2 . ASP D 4 89  ? 43.06100 32.67000 11.54200  1.000 113.27000 -1 89   ASP N    OD2 1 
ATOM   6211 N N   . THR D 4 90  ? 37.94800 35.12500 10.11000  1.000 109.77000 ?  90   THR N    N   1 
ATOM   6212 C CA  . THR D 4 90  ? 37.27200 36.33100 9.65400   1.000 109.01000 ?  90   THR N    CA  1 
ATOM   6213 C C   . THR D 4 90  ? 36.37500 36.82600 10.77800  1.000 108.43000 ?  90   THR N    C   1 
ATOM   6214 O O   . THR D 4 90  ? 35.35700 36.20200 11.10700  1.000 106.34000 ?  90   THR N    O   1 
ATOM   6215 C CB  . THR D 4 90  ? 36.48500 36.06800 8.37300   1.000 110.39000 ?  90   THR N    CB  1 
ATOM   6216 O OG1 . THR D 4 90  ? 37.38400 36.07300 7.26300   1.000 105.65000 ?  90   THR N    OG1 1 
ATOM   6217 C CG2 . THR D 4 90  ? 35.43600 37.15700 8.14000   1.000 111.27000 ?  90   THR N    CG2 1 
ATOM   6218 N N   . ALA D 4 91  ? 36.76700 37.93500 11.39000  1.000 104.50000 ?  91   ALA N    N   1 
ATOM   6219 C CA  . ALA D 4 91  ? 36.06400 38.39000 12.57300  1.000 103.23000 ?  91   ALA N    CA  1 
ATOM   6220 C C   . ALA D 4 91  ? 36.43400 39.83800 12.83300  1.000 100.97000 ?  91   ALA N    C   1 
ATOM   6221 O O   . ALA D 4 91  ? 37.47000 40.32600 12.37000  1.000 98.86000  ?  91   ALA N    O   1 
ATOM   6222 C CB  . ALA D 4 91  ? 36.40800 37.51800 13.78500  1.000 101.72000 ?  91   ALA N    CB  1 
ATOM   6223 N N   . VAL D 4 92  ? 35.54700 40.52700 13.55400  1.000 101.53000 ?  92   VAL N    N   1 
ATOM   6224 C CA  . VAL D 4 92  ? 35.91800 41.77600 14.20300  1.000 100.91000 ?  92   VAL N    CA  1 
ATOM   6225 C C   . VAL D 4 92  ? 36.75700 41.46200 15.43300  1.000 97.44000  ?  92   VAL N    C   1 
ATOM   6226 O O   . VAL D 4 92  ? 36.47100 40.52200 16.18800  1.000 91.87000  ?  92   VAL N    O   1 
ATOM   6227 C CB  . VAL D 4 92  ? 34.66400 42.59600 14.54200  1.000 96.65000  ?  92   VAL N    CB  1 
ATOM   6228 C CG1 . VAL D 4 92  ? 34.01600 43.01000 13.28300  1.000 102.07000 ?  92   VAL N    CG1 1 
ATOM   6229 C CG2 . VAL D 4 92  ? 33.66600 41.74500 15.27700  1.000 98.88000  ?  92   VAL N    CG2 1 
ATOM   6230 N N   . TYR D 4 93  ? 37.82500 42.22200 15.61400  1.000 96.61000  ?  93   TYR N    N   1 
ATOM   6231 C CA  . TYR D 4 93  ? 38.89300 41.87900 16.54400  1.000 94.59000  ?  93   TYR N    CA  1 
ATOM   6232 C C   . TYR D 4 93  ? 39.01400 42.97600 17.58600  1.000 95.20000  ?  93   TYR N    C   1 
ATOM   6233 O O   . TYR D 4 93  ? 39.45400 44.08600 17.27600  1.000 95.94000  ?  93   TYR N    O   1 
ATOM   6234 C CB  . TYR D 4 93  ? 40.20800 41.68700 15.79800  1.000 101.95000 ?  93   TYR N    CB  1 
ATOM   6235 C CG  . TYR D 4 93  ? 40.44000 40.27800 15.33600  1.000 100.46000 ?  93   TYR N    CG  1 
ATOM   6236 C CD1 . TYR D 4 93  ? 39.76100 39.75600 14.25100  1.000 97.94000  ?  93   TYR N    CD1 1 
ATOM   6237 C CD2 . TYR D 4 93  ? 41.36400 39.47900 15.97900  1.000 99.99000  ?  93   TYR N    CD2 1 
ATOM   6238 C CE1 . TYR D 4 93  ? 39.98400 38.46000 13.83100  1.000 101.71000 ?  93   TYR N    CE1 1 
ATOM   6239 C CE2 . TYR D 4 93  ? 41.59400 38.19600 15.57500  1.000 102.38000 ?  93   TYR N    CE2 1 
ATOM   6240 C CZ  . TYR D 4 93  ? 40.91000 37.68100 14.49900  1.000 102.99000 ?  93   TYR N    CZ  1 
ATOM   6241 O OH  . TYR D 4 93  ? 41.16600 36.38000 14.10400  1.000 101.54000 ?  93   TYR N    OH  1 
ATOM   6242 N N   . TYR D 4 94  ? 38.65900 42.65400 18.82600  1.000 99.09000  ?  94   TYR N    N   1 
ATOM   6243 C CA  . TYR D 4 94  ? 38.53400 43.65200 19.86900  1.000 88.72000  ?  94   TYR N    CA  1 
ATOM   6244 C C   . TYR D 4 94  ? 39.77700 43.67300 20.73900  1.000 85.29000  ?  94   TYR N    C   1 
ATOM   6245 O O   . TYR D 4 94  ? 40.39300 42.64000 21.00300  1.000 80.48000  ?  94   TYR N    O   1 
ATOM   6246 C CB  . TYR D 4 94  ? 37.31100 43.38300 20.72300  1.000 86.45000  ?  94   TYR N    CB  1 
ATOM   6247 C CG  . TYR D 4 94  ? 36.02700 43.40900 19.94200  1.000 91.50000  ?  94   TYR N    CG  1 
ATOM   6248 C CD1 . TYR D 4 94  ? 35.34700 44.59000 19.73100  1.000 91.40000  ?  94   TYR N    CD1 1 
ATOM   6249 C CD2 . TYR D 4 94  ? 35.46800 42.23200 19.45100  1.000 92.58000  ?  94   TYR N    CD2 1 
ATOM   6250 C CE1 . TYR D 4 94  ? 34.15300 44.60500 19.02700  1.000 96.96000  ?  94   TYR N    CE1 1 
ATOM   6251 C CE2 . TYR D 4 94  ? 34.27100 42.23600 18.75300  1.000 93.29000  ?  94   TYR N    CE2 1 
ATOM   6252 C CZ  . TYR D 4 94  ? 33.61300 43.43100 18.53400  1.000 98.00000  ?  94   TYR N    CZ  1 
ATOM   6253 O OH  . TYR D 4 94  ? 32.41000 43.46200 17.83200  1.000 100.03000 ?  94   TYR N    OH  1 
ATOM   6254 N N   . CYS D 4 95  ? 40.13700 44.88300 21.15300  1.000 92.16000  ?  95   CYS N    N   1 
ATOM   6255 C CA  . CYS D 4 95  ? 41.20800 45.19200 22.09200  1.000 89.35000  ?  95   CYS N    CA  1 
ATOM   6256 C C   . CYS D 4 95  ? 40.61900 45.37500 23.49100  1.000 89.14000  ?  95   CYS N    C   1 
ATOM   6257 O O   . CYS D 4 95  ? 39.56800 46.00800 23.63700  1.000 90.88000  ?  95   CYS N    O   1 
ATOM   6258 C CB  . CYS D 4 95  ? 41.88600 46.47700 21.61600  1.000 92.39000  ?  95   CYS N    CB  1 
ATOM   6259 S SG  . CYS D 4 95  ? 43.22500 47.09100 22.58700  1.000 107.64000 ?  95   CYS N    SG  1 
ATOM   6260 N N   . ARG D 4 96  ? 41.27100 44.82700 24.52400  1.000 83.59000  ?  96   ARG N    N   1 
ATOM   6261 C CA  . ARG D 4 96  ? 40.63200 44.87300 25.84700  1.000 85.63000  ?  96   ARG N    CA  1 
ATOM   6262 C C   . ARG D 4 96  ? 41.61500 44.88700 27.01000  1.000 85.28000  ?  96   ARG N    C   1 
ATOM   6263 O O   . ARG D 4 96  ? 42.44100 43.97700 27.13200  1.000 85.42000  ?  96   ARG N    O   1 
ATOM   6264 C CB  . ARG D 4 96  ? 39.70600 43.68300 26.01900  1.000 84.34000  ?  96   ARG N    CB  1 
ATOM   6265 C CG  . ARG D 4 96  ? 38.73900 43.77900 27.16400  1.000 83.42000  ?  96   ARG N    CG  1 
ATOM   6266 C CD  . ARG D 4 96  ? 38.63000 42.44400 27.85900  1.000 80.92000  ?  96   ARG N    CD  1 
ATOM   6267 N NE  . ARG D 4 96  ? 37.65700 42.44800 28.94200  1.000 78.02000  ?  96   ARG N    NE  1 
ATOM   6268 C CZ  . ARG D 4 96  ? 37.11500 41.34900 29.44600  1.000 76.45000  ?  96   ARG N    CZ  1 
ATOM   6269 N NH1 . ARG D 4 96  ? 37.54800 40.14500 29.10700  1.000 75.69000  ?  96   ARG N    NH1 1 
ATOM   6270 N NH2 . ARG D 4 96  ? 36.10200 41.46000 30.29400  1.000 79.18000  ?  96   ARG N    NH2 1 
ATOM   6271 N N   . LEU D 4 97  ? 41.45800 45.86900 27.91200  1.000 89.61000  ?  97   LEU N    N   1 
ATOM   6272 C CA  . LEU D 4 97  ? 42.38000 46.11300 29.03000  1.000 84.24000  ?  97   LEU N    CA  1 
ATOM   6273 C C   . LEU D 4 97  ? 41.60900 46.16700 30.34100  1.000 76.27000  ?  97   LEU N    C   1 
ATOM   6274 O O   . LEU D 4 97  ? 40.88100 47.13300 30.57000  1.000 79.21000  ?  97   LEU N    O   1 
ATOM   6275 C CB  . LEU D 4 97  ? 43.11800 47.43100 28.82900  1.000 82.92000  ?  97   LEU N    CB  1 
ATOM   6276 C CG  . LEU D 4 97  ? 43.71800 48.08100 30.06200  1.000 74.93000  ?  97   LEU N    CG  1 
ATOM   6277 C CD1 . LEU D 4 97  ? 45.02400 47.37500 30.39600  1.000 75.69000  ?  97   LEU N    CD1 1 
ATOM   6278 C CD2 . LEU D 4 97  ? 43.89400 49.56700 29.84800  1.000 74.53000  ?  97   LEU N    CD2 1 
ATOM   6279 N N   . ILE D 4 98  ? 41.79000 45.16400 31.20800  1.000 76.01000  ?  98   ILE N    N   1 
ATOM   6280 C CA  . ILE D 4 98  ? 41.16000 45.11700 32.53700  1.000 79.40000  ?  98   ILE N    CA  1 
ATOM   6281 C C   . ILE D 4 98  ? 42.15000 45.63500 33.58300  1.000 79.08000  ?  98   ILE N    C   1 
ATOM   6282 O O   . ILE D 4 98  ? 43.08300 44.93700 33.99600  1.000 77.53000  ?  98   ILE N    O   1 
ATOM   6283 C CB  . ILE D 4 98  ? 40.68100 43.71100 32.90300  1.000 76.18000  ?  98   ILE N    CB  1 
ATOM   6284 C CG1 . ILE D 4 98  ? 39.78800 43.15000 31.81200  1.000 78.07000  ?  98   ILE N    CG1 1 
ATOM   6285 C CG2 . ILE D 4 98  ? 39.95100 43.74500 34.22100  1.000 73.62000  ?  98   ILE N    CG2 1 
ATOM   6286 C CD1 . ILE D 4 98  ? 40.41600 42.05000 31.08400  1.000 77.42000  ?  98   ILE N    CD1 1 
ATOM   6287 N N   . GLN D 4 99  ? 41.89900 46.84100 34.09500  1.000 81.70000  ?  99   GLN N    N   1 
ATOM   6288 C CA  . GLN D 4 99  ? 42.72500 47.38000 35.20800  1.000 79.73000  ?  99   GLN N    CA  1 
ATOM   6289 C C   . GLN D 4 99  ? 41.84900 47.34800 36.45900  1.000 79.87000  ?  99   GLN N    C   1 
ATOM   6290 O O   . GLN D 4 99  ? 42.21900 46.64600 37.40900  1.000 86.85000  ?  99   GLN N    O   1 
ATOM   6291 C CB  . GLN D 4 99  ? 43.17900 48.80300 34.90300  1.000 82.28000  ?  99   GLN N    CB  1 
ATOM   6292 C CG  . GLN D 4 99  ? 44.23900 48.88800 33.81900  1.000 74.93000  ?  99   GLN N    CG  1 
ATOM   6293 C CD  . GLN D 4 99  ? 44.97300 50.20400 33.87900  1.000 78.91000  ?  99   GLN N    CD  1 
ATOM   6294 O OE1 . GLN D 4 99  ? 46.17200 50.25500 34.14300  1.000 88.62000  ?  99   GLN N    OE1 1 
ATOM   6295 N NE2 . GLN D 4 99  ? 44.24700 51.28600 33.65700  1.000 82.39000  ?  99   GLN N    NE2 1 
ATOM   6296 N N   . ASN D 4 100 ? 40.76400 48.11900 36.47800  1.000 79.53000  ?  100  ASN N    N   1 
ATOM   6297 C CA  . ASN D 4 100 ? 39.77000 48.03200 37.58000  1.000 79.52000  ?  100  ASN N    CA  1 
ATOM   6298 C C   . ASN D 4 100 ? 38.42100 48.10500 36.87500  1.000 86.28000  ?  100  ASN N    C   1 
ATOM   6299 O O   . ASN D 4 100 ? 37.39100 47.90400 37.53500  1.000 79.73000  ?  100  ASN N    O   1 
ATOM   6300 C CB  . ASN D 4 100 ? 39.93800 49.11600 38.64200  1.000 86.10000  ?  100  ASN N    CB  1 
ATOM   6301 C CG  . ASN D 4 100 ? 38.91500 49.01400 39.75200  1.000 83.28000  ?  100  ASN N    CG  1 
ATOM   6302 O OD1 . ASN D 4 100 ? 38.82800 47.99400 40.43000  1.000 86.37000  ?  100  ASN N    OD1 1 
ATOM   6303 N ND2 . ASN D 4 100 ? 38.13300 50.06400 39.93900  1.000 86.42000  ?  100  ASN N    ND2 1 
ATOM   6304 N N   . ARG D 4 101 ? 38.45800 48.38100 35.57100  1.000 85.20000  ?  101  ARG N    N   1 
ATOM   6305 C CA  . ARG D 4 101 ? 37.22800 48.45200 34.74400  1.000 93.96000  ?  101  ARG N    CA  1 
ATOM   6306 C C   . ARG D 4 101 ? 37.55100 47.68500 33.45900  1.000 101.57000 ?  101  ARG N    C   1 
ATOM   6307 O O   . ARG D 4 101 ? 38.73900 47.65000 33.10800  1.000 110.84000 ?  101  ARG N    O   1 
ATOM   6308 C CB  . ARG D 4 101 ? 36.87400 49.92400 34.54000  1.000 96.68000  ?  101  ARG N    CB  1 
ATOM   6309 C CG  . ARG D 4 101 ? 36.97300 50.74800 35.81600  1.000 99.73000  ?  101  ARG N    CG  1 
ATOM   6310 C CD  . ARG D 4 101 ? 36.88700 52.24700 35.61000  1.000 115.04000 ?  101  ARG N    CD  1 
ATOM   6311 N NE  . ARG D 4 101 ? 35.55900 52.69000 35.21700  1.000 128.48000 ?  101  ARG N    NE  1 
ATOM   6312 C CZ  . ARG D 4 101 ? 34.81200 53.53600 35.91700  1.000 132.62000 ?  101  ARG N    CZ  1 
ATOM   6313 N NH1 . ARG D 4 101 ? 35.12600 53.81300 37.17000  1.000 124.77000 ?  101  ARG N    NH1 1 
ATOM   6314 N NH2 . ARG D 4 101 ? 33.75100 54.09800 35.36400  1.000 134.93000 ?  101  ARG N    NH2 1 
ATOM   6315 N N   . ASP D 4 102 ? 36.52600 47.14600 32.80400  1.000 93.05000  ?  102  ASP N    N   1 
ATOM   6316 C CA  . ASP D 4 102 ? 36.71300 46.47100 31.50400  1.000 91.81000  ?  102  ASP N    CA  1 
ATOM   6317 C C   . ASP D 4 102 ? 36.71900 47.56400 30.44500  1.000 91.65000  ?  102  ASP N    C   1 
ATOM   6318 O O   . ASP D 4 102 ? 35.62700 47.98200 30.02700  1.000 96.24000  ?  102  ASP N    O   1 
ATOM   6319 C CB  . ASP D 4 102 ? 35.55700 45.52000 31.22100  1.000 92.66000  ?  102  ASP N    CB  1 
ATOM   6320 C CG  . ASP D 4 102 ? 35.92200 44.06500 31.40500  1.000 87.27000  ?  102  ASP N    CG  1 
ATOM   6321 O OD1 . ASP D 4 102 ? 37.06800 43.72400 31.09600  1.000 74.95000  ?  102  ASP N    OD1 1 
ATOM   6322 O OD2 . ASP D 4 102 ? 35.05100 43.29500 31.84600  1.000 89.39000  ?  102  ASP N    OD2 1 
ATOM   6323 N N   . TYR D 4 103 ? 37.89400 48.04200 30.06000  1.000 89.64000  ?  103  TYR N    N   1 
ATOM   6324 C CA  . TYR D 4 103 ? 37.94200 49.03100 28.96200  1.000 93.30000  ?  103  TYR N    CA  1 
ATOM   6325 C C   . TYR D 4 103 ? 37.99000 48.25900 27.64500  1.000 91.25000  ?  103  TYR N    C   1 
ATOM   6326 O O   . TYR D 4 103 ? 39.03500 47.65000 27.37600  1.000 86.96000  ?  103  TYR N    O   1 
ATOM   6327 C CB  . TYR D 4 103 ? 39.16600 49.92700 29.12900  1.000 92.10000  ?  103  TYR N    CB  1 
ATOM   6328 C CG  . TYR D 4 103 ? 39.13700 50.81600 30.34400  1.000 102.15000 ?  103  TYR N    CG  1 
ATOM   6329 C CD1 . TYR D 4 103 ? 38.42900 52.00500 30.33500  1.000 110.83000 ?  103  TYR N    CD1 1 
ATOM   6330 C CD2 . TYR D 4 103 ? 39.81900 50.47600 31.49800  1.000 99.25000  ?  103  TYR N    CD2 1 
ATOM   6331 C CE1 . TYR D 4 103 ? 38.39600 52.83400 31.44200  1.000 105.24000 ?  103  TYR N    CE1 1 
ATOM   6332 C CE2 . TYR D 4 103 ? 39.79800 51.29500 32.61500  1.000 102.20000 ?  103  TYR N    CE2 1 
ATOM   6333 C CZ  . TYR D 4 103 ? 39.08300 52.47800 32.58600  1.000 103.87000 ?  103  TYR N    CZ  1 
ATOM   6334 O OH  . TYR D 4 103 ? 39.05100 53.30200 33.68100  1.000 107.95000 ?  103  TYR N    OH  1 
ATOM   6335 N N   . TRP D 4 104 ? 36.90700 48.24800 26.86500  1.000 90.23000  ?  104  TRP N    N   1 
ATOM   6336 C CA  . TRP D 4 104 ? 37.03600 47.46000 25.61200  1.000 90.29000  ?  104  TRP N    CA  1 
ATOM   6337 C C   . TRP D 4 104 ? 37.35700 48.38200 24.43400  1.000 101.98000 ?  104  TRP N    C   1 
ATOM   6338 O O   . TRP D 4 104 ? 37.63900 49.56600 24.67500  1.000 110.33000 ?  104  TRP N    O   1 
ATOM   6339 C CB  . TRP D 4 104 ? 35.75700 46.66300 25.34500  1.000 86.96000  ?  104  TRP N    CB  1 
ATOM   6340 C CG  . TRP D 4 104 ? 35.52800 45.48500 26.23800  1.000 81.39000  ?  104  TRP N    CG  1 
ATOM   6341 C CD1 . TRP D 4 104 ? 35.26400 45.49600 27.57500  1.000 84.58000  ?  104  TRP N    CD1 1 
ATOM   6342 C CD2 . TRP D 4 104 ? 35.54100 44.10400 25.84200  1.000 87.37000  ?  104  TRP N    CD2 1 
ATOM   6343 N NE1 . TRP D 4 104 ? 35.10900 44.21800 28.03700  1.000 82.99000  ?  104  TRP N    NE1 1 
ATOM   6344 C CE2 . TRP D 4 104 ? 35.27500 43.34200 26.99700  1.000 83.87000  ?  104  TRP N    CE2 1 
ATOM   6345 C CE3 . TRP D 4 104 ? 35.75500 43.44000 24.63000  1.000 85.36000  ?  104  TRP N    CE3 1 
ATOM   6346 C CZ2 . TRP D 4 104 ? 35.21600 41.95100 26.97000  1.000 81.54000  ?  104  TRP N    CZ2 1 
ATOM   6347 C CZ3 . TRP D 4 104 ? 35.69600 42.06600 24.60500  1.000 82.39000  ?  104  TRP N    CZ3 1 
ATOM   6348 C CH2 . TRP D 4 104 ? 35.43100 41.33400 25.76100  1.000 78.95000  ?  104  TRP N    CH2 1 
ATOM   6349 N N   . GLY D 4 105 ? 37.31300 47.85100 23.21000  1.000 96.58000  ?  105  GLY N    N   1 
ATOM   6350 C CA  . GLY D 4 105 ? 37.57500 48.65500 22.00200  1.000 100.63000 ?  105  GLY N    CA  1 
ATOM   6351 C C   . GLY D 4 105 ? 36.51900 48.39100 20.94600  1.000 109.41000 ?  105  GLY N    C   1 
ATOM   6352 O O   . GLY D 4 105 ? 35.85000 47.34900 21.03700  1.000 112.90000 ?  105  GLY N    O   1 
ATOM   6353 N N   . GLN D 4 106 ? 36.36000 49.29800 19.98400  1.000 103.91000 ?  106  GLN N    N   1 
ATOM   6354 C CA  . GLN D 4 106 ? 35.28300 49.14600 18.97300  1.000 97.53000  ?  106  GLN N    CA  1 
ATOM   6355 C C   . GLN D 4 106 ? 35.56100 47.89300 18.14600  1.000 106.58000 ?  106  GLN N    C   1 
ATOM   6356 O O   . GLN D 4 106 ? 34.60200 47.15800 17.87100  1.000 108.80000 ?  106  GLN N    O   1 
ATOM   6357 C CB  . GLN D 4 106 ? 35.20100 50.39400 18.09900  1.000 98.61000  ?  106  GLN N    CB  1 
ATOM   6358 C CG  . GLN D 4 106 ? 34.99000 51.68000 18.88600  1.000 109.06000 ?  106  GLN N    CG  1 
ATOM   6359 C CD  . GLN D 4 106 ? 36.26200 52.20100 19.50800  1.000 118.53000 ?  106  GLN N    CD  1 
ATOM   6360 O OE1 . GLN D 4 106 ? 37.33700 51.62600 19.35100  1.000 117.85000 ?  106  GLN N    OE1 1 
ATOM   6361 N NE2 . GLN D 4 106 ? 36.14900 53.30900 20.22100  1.000 119.82000 ?  106  GLN N    NE2 1 
ATOM   6362 N N   . GLY D 4 107 ? 36.81400 47.67800 17.74000  1.000 111.72000 ?  107  GLY N    N   1 
ATOM   6363 C CA  . GLY D 4 107 ? 37.16800 46.42800 17.03800  1.000 107.13000 ?  107  GLY N    CA  1 
ATOM   6364 C C   . GLY D 4 107 ? 37.23600 46.54200 15.52800  1.000 106.97000 ?  107  GLY N    C   1 
ATOM   6365 O O   . GLY D 4 107 ? 36.17700 46.43500 14.89100  1.000 106.47000 ?  107  GLY N    O   1 
ATOM   6366 N N   . THR D 4 108 ? 38.43500 46.73000 14.96800  1.000 109.83000 ?  108  THR N    N   1 
ATOM   6367 C CA  . THR D 4 108 ? 38.59100 46.72600 13.51700  1.000 107.82000 ?  108  THR N    CA  1 
ATOM   6368 C C   . THR D 4 108 ? 38.17300 45.39200 12.90200  1.000 102.65000 ?  108  THR N    C   1 
ATOM   6369 O O   . THR D 4 108 ? 38.23200 44.32900 13.53000  1.000 96.38000  ?  108  THR N    O   1 
ATOM   6370 C CB  . THR D 4 108 ? 40.04200 47.01500 13.13600  1.000 108.43000 ?  108  THR N    CB  1 
ATOM   6371 O OG1 . THR D 4 108 ? 40.91300 46.23100 13.96400  1.000 95.30000  ?  108  THR N    OG1 1 
ATOM   6372 C CG2 . THR D 4 108 ? 40.36300 48.51200 13.28900  1.000 115.29000 ?  108  THR N    CG2 1 
ATOM   6373 N N   . GLN D 4 109 ? 37.75300 45.45900 11.64100  1.000 106.52000 ?  109  GLN N    N   1 
ATOM   6374 C CA  . GLN D 4 109 ? 37.36000 44.26100 10.91500  1.000 102.29000 ?  109  GLN N    CA  1 
ATOM   6375 C C   . GLN D 4 109 ? 38.58700 43.61200 10.29600  1.000 101.08000 ?  109  GLN N    C   1 
ATOM   6376 O O   . GLN D 4 109 ? 39.55500 44.29000 9.93600   1.000 102.95000 ?  109  GLN N    O   1 
ATOM   6377 C CB  . GLN D 4 109 ? 36.32500 44.58600 9.83900   1.000 95.12000  ?  109  GLN N    CB  1 
ATOM   6378 C CG  . GLN D 4 109 ? 35.97000 43.42800 8.93800   1.000 95.96000  ?  109  GLN N    CG  1 
ATOM   6379 C CD  . GLN D 4 109 ? 34.93200 42.49800 9.53800   1.000 93.75000  ?  109  GLN N    CD  1 
ATOM   6380 O OE1 . GLN D 4 109 ? 33.79100 42.88400 9.77700   1.000 91.76000  ?  109  GLN N    OE1 1 
ATOM   6381 N NE2 . GLN D 4 109 ? 35.30500 41.24400 9.71600   1.000 98.95000  ?  109  GLN N    NE2 1 
ATOM   6382 N N   . VAL D 4 110 ? 38.56200 42.28400 10.24000  1.000 92.81000  ?  110  VAL N    N   1 
ATOM   6383 C CA  . VAL D 4 110 ? 39.59000 41.51700 9.56200   1.000 88.61000  ?  110  VAL N    CA  1 
ATOM   6384 C C   . VAL D 4 110 ? 38.90400 40.36500 8.85300   1.000 99.10000  ?  110  VAL N    C   1 
ATOM   6385 O O   . VAL D 4 110 ? 38.44800 39.41000 9.49600   1.000 97.95000  ?  110  VAL N    O   1 
ATOM   6386 C CB  . VAL D 4 110 ? 40.69100 41.06800 10.53700  1.000 89.06000  ?  110  VAL N    CB  1 
ATOM   6387 C CG1 . VAL D 4 110 ? 41.37100 39.80800 10.09100  1.000 88.10000  ?  110  VAL N    CG1 1 
ATOM   6388 C CG2 . VAL D 4 110 ? 41.72900 42.15000 10.61700  1.000 91.47000  ?  110  VAL N    CG2 1 
ATOM   6389 N N   . THR D 4 111 ? 38.85700 40.47800 7.52000   1.000 110.41000 ?  111  THR N    N   1 
ATOM   6390 C CA  . THR D 4 111 ? 38.27200 39.41500 6.66800   1.000 107.81000 ?  111  THR N    CA  1 
ATOM   6391 C C   . THR D 4 111 ? 39.38800 38.88600 5.76700   1.000 105.89000 ?  111  THR N    C   1 
ATOM   6392 O O   . THR D 4 111 ? 40.13400 39.71700 5.22500   1.000 110.38000 ?  111  THR N    O   1 
ATOM   6393 C CB  . THR D 4 111 ? 37.13100 39.97400 5.81500   1.000 103.75000 ?  111  THR N    CB  1 
ATOM   6394 O OG1 . THR D 4 111 ? 37.61100 41.17000 5.20400   1.000 108.03000 ?  111  THR N    OG1 1 
ATOM   6395 C CG2 . THR D 4 111 ? 35.88800 40.28500 6.61800   1.000 102.93000 ?  111  THR N    CG2 1 
ATOM   6396 N N   . VAL D 4 112 ? 39.51600 37.56300 5.65100   1.000 107.03000 ?  112  VAL N    N   1 
ATOM   6397 C CA  . VAL D 4 112 ? 40.64500 36.97700 4.87400   1.000 117.36000 ?  112  VAL N    CA  1 
ATOM   6398 C C   . VAL D 4 112 ? 40.09400 36.15200 3.70900   1.000 125.50000 ?  112  VAL N    C   1 
ATOM   6399 O O   . VAL D 4 112 ? 39.23900 35.28600 3.96000   1.000 125.08000 ?  112  VAL N    O   1 
ATOM   6400 C CB  . VAL D 4 112 ? 41.54200 36.11500 5.77900   1.000 112.51000 ?  112  VAL N    CB  1 
ATOM   6401 C CG1 . VAL D 4 112 ? 42.56000 35.32500 4.97300   1.000 112.65000 ?  112  VAL N    CG1 1 
ATOM   6402 C CG2 . VAL D 4 112 ? 42.23200 36.94900 6.84600   1.000 116.57000 ?  112  VAL N    CG2 1 
ATOM   6403 N N   . SER D 4 113 ? 40.58100 36.40900 2.49100   1.000 122.22000 ?  113  SER N    N   1 
ATOM   6404 C CA  . SER D 4 113 ? 40.14900 35.62700 1.30300   1.000 117.96000 ?  113  SER N    CA  1 
ATOM   6405 C C   . SER D 4 113 ? 41.27800 34.68400 0.88500   1.000 115.69000 ?  113  SER N    C   1 
ATOM   6406 O O   . SER D 4 113 ? 42.38700 34.82500 1.43000   1.000 113.70000 ?  113  SER N    O   1 
ATOM   6407 C CB  . SER D 4 113 ? 39.74200 36.53100 0.18000   1.000 114.28000 ?  113  SER N    CB  1 
ATOM   6408 O OG  . SER D 4 113 ? 39.26900 35.77400 -0.92300  1.000 115.19000 ?  113  SER N    OG  1 
ATOM   6409 N N   . SER D 4 114 ? 41.01800 33.77900 -0.06100  1.000 113.48000 ?  114  SER N    N   1 
ATOM   6410 C CA  . SER D 4 114 ? 42.04100 32.75800 -0.40800  1.000 118.43000 ?  114  SER N    CA  1 
ATOM   6411 C C   . SER D 4 114 ? 42.83000 33.12600 -1.66900  1.000 121.73000 ?  114  SER N    C   1 
ATOM   6412 O O   . SER D 4 114 ? 43.91000 32.53800 -1.85800  1.000 121.93000 ?  114  SER N    O   1 
ATOM   6413 C CB  . SER D 4 114 ? 41.40200 31.40800 -0.55500  1.000 115.64000 ?  114  SER N    CB  1 
ATOM   6414 O OG  . SER D 4 114 ? 42.38500 30.41500 -0.79900  1.000 121.80000 ?  114  SER N    OG  1 
ATOM   6415 N N   . HIS D 4 115 ? 42.32900 34.04400 -2.49800  1.000 120.08000 ?  115  HIS N    N   1 
ATOM   6416 C CA  . HIS D 4 115 ? 43.02400 34.32900 -3.77400  1.000 121.73000 ?  115  HIS N    CA  1 
ATOM   6417 C C   . HIS D 4 115 ? 43.24800 33.08100 -4.66400  1.000 130.10000 ?  115  HIS N    C   1 
ATOM   6418 O O   . HIS D 4 115 ? 42.73200 32.97300 -5.79400  1.000 114.19000 ?  115  HIS N    O   1 
ATOM   6419 C CB  . HIS D 4 115 ? 44.36800 35.03200 -3.50500  1.000 114.57000 ?  115  HIS N    CB  1 
ATOM   6420 C CG  . HIS D 4 115 ? 44.72600 36.06800 -4.53000  1.000 124.41000 ?  115  HIS N    CG  1 
ATOM   6421 N ND1 . HIS D 4 115 ? 44.08300 37.28500 -4.63000  1.000 122.84000 ?  115  HIS N    ND1 1 
ATOM   6422 C CD2 . HIS D 4 115 ? 45.68100 36.06600 -5.49500  1.000 127.31000 ?  115  HIS N    CD2 1 
ATOM   6423 C CE1 . HIS D 4 115 ? 44.61700 37.98200 -5.61900  1.000 119.74000 ?  115  HIS N    CE1 1 
ATOM   6424 N NE2 . HIS D 4 115 ? 45.58900 37.26500 -6.15900  1.000 124.75000 ?  115  HIS N    NE2 1 
HETATM 6425 O O   . HOH E 5 .   ? 38.92800 5.19600  44.82900  1.000 86.89000  ?  1101 HOH AAZA O   1 
HETATM 6426 O O   . HOH E 5 .   ? 27.98900 38.25700 31.36700  1.000 75.16000  ?  1102 HOH AAZA O   1 
HETATM 6427 O O   . HOH E 5 .   ? 43.34000 24.36800 39.43000  1.000 82.95000  ?  1103 HOH AAZA O   1 
HETATM 6428 O O   . HOH E 5 .   ? 44.10400 1.28300  67.19600  1.000 104.89000 ?  1104 HOH AAZA O   1 
HETATM 6429 O O   . HOH E 5 .   ? 30.16900 21.98100 34.53700  1.000 74.80000  ?  1105 HOH AAZA O   1 
HETATM 6430 O O   . HOH E 5 .   ? 47.06400 17.91700 70.44000  1.000 73.66000  ?  1106 HOH AAZA O   1 
HETATM 6431 O O   . HOH E 5 .   ? 47.28900 24.57900 42.98500  1.000 83.23000  ?  1107 HOH AAZA O   1 
HETATM 6432 O O   . HOH E 5 .   ? 63.46300 39.59900 85.80200  1.000 68.79000  ?  1108 HOH AAZA O   1 
HETATM 6433 O O   . HOH E 5 .   ? 29.58300 37.28800 68.99500  1.000 79.67000  ?  1109 HOH AAZA O   1 
HETATM 6434 O O   . HOH E 5 .   ? 42.53900 0.35100  64.06500  1.000 87.76000  ?  1110 HOH AAZA O   1 
HETATM 6435 O O   . HOH F 5 .   ? 25.95000 40.01900 30.52000  1.000 83.34000  ?  201  HOH C    O   1 
HETATM 6436 O O   . HOH F 5 .   ? 21.03000 41.80200 27.65900  1.000 98.77000  ?  202  HOH C    O   1 
HETATM 6437 O O   . HOH G 5 .   ? 32.49400 50.31400 41.72200  1.000 78.32000  ?  201  HOH R    O   1 
HETATM 6438 O O   . HOH G 5 .   ? 35.73200 68.80500 60.03000  1.000 75.04000  ?  202  HOH R    O   1 
HETATM 6439 O O   . HOH G 5 .   ? 40.96300 44.13100 58.47600  1.000 70.78000  ?  203  HOH R    O   1 
HETATM 6440 O O   . HOH G 5 .   ? 40.38500 48.60000 67.28200  1.000 62.22000  ?  204  HOH R    O   1 
HETATM 6441 O O   . HOH G 5 .   ? 38.15100 46.23600 58.91700  1.000 67.31000  ?  205  HOH R    O   1 
HETATM 6442 O O   . HOH G 5 .   ? 23.10100 48.73200 78.72900  1.000 85.03000  ?  206  HOH R    O   1 
HETATM 6443 O O   . HOH H 5 .   ? 49.77700 37.26600 39.71700  1.000 74.50000  ?  201  HOH N    O   1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   543  ?    ?   ?   AAZA . n 
A 1 2   GLY 2   544  ?    ?   ?   AAZA . n 
A 1 3   SER 3   545  ?    ?   ?   AAZA . n 
A 1 4   SER 4   546  ?    ?   ?   AAZA . n 
A 1 5   HIS 5   547  ?    ?   ?   AAZA . n 
A 1 6   HIS 6   548  ?    ?   ?   AAZA . n 
A 1 7   HIS 7   549  ?    ?   ?   AAZA . n 
A 1 8   HIS 8   550  ?    ?   ?   AAZA . n 
A 1 9   HIS 9   551  ?    ?   ?   AAZA . n 
A 1 10  HIS 10  552  ?    ?   ?   AAZA . n 
A 1 11  SER 11  553  ?    ?   ?   AAZA . n 
A 1 12  SER 12  554  ?    ?   ?   AAZA . n 
A 1 13  GLY 13  555  ?    ?   ?   AAZA . n 
A 1 14  LEU 14  556  ?    ?   ?   AAZA . n 
A 1 15  VAL 15  557  ?    ?   ?   AAZA . n 
A 1 16  PRO 16  558  ?    ?   ?   AAZA . n 
A 1 17  ARG 17  559  ?    ?   ?   AAZA . n 
A 1 18  GLY 18  560  ?    ?   ?   AAZA . n 
A 1 19  SER 19  561  ?    ?   ?   AAZA . n 
A 1 20  HIS 20  562  ?    ?   ?   AAZA . n 
A 1 21  MET 21  563  ?    ?   ?   AAZA . n 
A 1 22  GLU 22  564  ?    ?   ?   AAZA . n 
A 1 23  GLU 23  565  ?    ?   ?   AAZA . n 
A 1 24  GLN 24  566  ?    ?   ?   AAZA . n 
A 1 25  MET 25  567  ?    ?   ?   AAZA . n 
A 1 26  ARG 26  568  ?    ?   ?   AAZA . n 
A 1 27  LEU 27  569  ?    ?   ?   AAZA . n 
A 1 28  PRO 28  570  570  PRO PRO AAZA . n 
A 1 29  SER 29  571  571  SER SER AAZA . n 
A 1 30  ALA 30  572  572  ALA ALA AAZA . n 
A 1 31  ASP 31  573  573  ASP ASP AAZA . n 
A 1 32  VAL 32  574  574  VAL VAL AAZA . n 
A 1 33  TYR 33  575  575  TYR TYR AAZA . n 
A 1 34  ARG 34  576  576  ARG ARG AAZA . n 
A 1 35  PHE 35  577  577  PHE PHE AAZA . n 
A 1 36  ALA 36  578  578  ALA ALA AAZA . n 
A 1 37  GLU 37  579  579  GLU GLU AAZA . n 
A 1 38  PRO 38  580  580  PRO PRO AAZA . n 
A 1 39  ASP 39  581  581  ASP ASP AAZA . n 
A 1 40  SER 40  582  582  SER SER AAZA . n 
A 1 41  GLU 41  583  583  GLU GLU AAZA . n 
A 1 42  GLU 42  584  584  GLU GLU AAZA . n 
A 1 43  ASN 43  585  585  ASN ASN AAZA . n 
A 1 44  ILE 44  586  586  ILE ILE AAZA . n 
A 1 45  ILE 45  587  587  ILE ILE AAZA . n 
A 1 46  PHE 46  588  588  PHE PHE AAZA . n 
A 1 47  GLU 47  589  589  GLU GLU AAZA . n 
A 1 48  GLU 48  590  590  GLU GLU AAZA . n 
A 1 49  ASN 49  591  591  ASN ASN AAZA . n 
A 1 50  MET 50  592  ?    ?   ?   AAZA . n 
A 1 51  GLN 51  593  ?    ?   ?   AAZA . n 
A 1 52  PRO 52  594  ?    ?   ?   AAZA . n 
A 1 53  LYS 53  595  ?    ?   ?   AAZA . n 
A 1 54  ALA 54  596  596  ALA ALA AAZA . n 
A 1 55  GLY 55  597  597  GLY GLY AAZA . n 
A 1 56  ILE 56  598  598  ILE ILE AAZA . n 
A 1 57  PRO 57  599  599  PRO PRO AAZA . n 
A 1 58  ILE 58  600  600  ILE ILE AAZA . n 
A 1 59  ILE 59  601  601  ILE ILE AAZA . n 
A 1 60  LYS 60  602  602  LYS LYS AAZA . n 
A 1 61  ALA 61  603  603  ALA ALA AAZA . n 
A 1 62  GLY 62  604  604  GLY GLY AAZA . n 
A 1 63  THR 63  605  605  THR THR AAZA . n 
A 1 64  VAL 64  606  606  VAL VAL AAZA . n 
A 1 65  ILE 65  607  607  ILE ILE AAZA . n 
A 1 66  LYS 66  608  608  LYS LYS AAZA . n 
A 1 67  LEU 67  609  609  LEU LEU AAZA . n 
A 1 68  ILE 68  610  610  ILE ILE AAZA . n 
A 1 69  GLU 69  611  611  GLU GLU AAZA . n 
A 1 70  ARG 70  612  612  ARG ARG AAZA . n 
A 1 71  LEU 71  613  613  LEU LEU AAZA . n 
A 1 72  THR 72  614  614  THR THR AAZA . n 
A 1 73  TYR 73  615  615  TYR TYR AAZA . n 
A 1 74  HIS 74  616  616  HIS HIS AAZA . n 
A 1 75  MET 75  617  617  MET MET AAZA . n 
A 1 76  TYR 76  618  618  TYR TYR AAZA . n 
A 1 77  ALA 77  619  619  ALA ALA AAZA . n 
A 1 78  ASP 78  620  620  ASP ASP AAZA . n 
A 1 79  PRO 79  621  621  PRO PRO AAZA . n 
A 1 80  ASN 80  622  622  ASN ASN AAZA . n 
A 1 81  PHE 81  623  623  PHE PHE AAZA . n 
A 1 82  VAL 82  624  624  VAL VAL AAZA . n 
A 1 83  ARG 83  625  625  ARG ARG AAZA . n 
A 1 84  THR 84  626  626  THR THR AAZA . n 
A 1 85  PHE 85  627  627  PHE PHE AAZA . n 
A 1 86  LEU 86  628  628  LEU LEU AAZA . n 
A 1 87  THR 87  629  629  THR THR AAZA . n 
A 1 88  THR 88  630  630  THR THR AAZA . n 
A 1 89  TYR 89  631  631  TYR TYR AAZA . n 
A 1 90  ARG 90  632  632  ARG ARG AAZA . n 
A 1 91  SER 91  633  633  SER SER AAZA . n 
A 1 92  PHE 92  634  634  PHE PHE AAZA . n 
A 1 93  CYS 93  635  635  CYS CYS AAZA . n 
A 1 94  LYS 94  636  636  LYS LYS AAZA . n 
A 1 95  PRO 95  637  637  PRO PRO AAZA . n 
A 1 96  GLN 96  638  638  GLN GLN AAZA . n 
A 1 97  GLU 97  639  639  GLU GLU AAZA . n 
A 1 98  LEU 98  640  640  LEU LEU AAZA . n 
A 1 99  LEU 99  641  641  LEU LEU AAZA . n 
A 1 100 SER 100 642  642  SER SER AAZA . n 
A 1 101 LEU 101 643  643  LEU LEU AAZA . n 
A 1 102 ILE 102 644  644  ILE ILE AAZA . n 
A 1 103 ILE 103 645  645  ILE ILE AAZA . n 
A 1 104 GLU 104 646  646  GLU GLU AAZA . n 
A 1 105 ARG 105 647  647  ARG ARG AAZA . n 
A 1 106 PHE 106 648  648  PHE PHE AAZA . n 
A 1 107 GLU 107 649  649  GLU GLU AAZA . n 
A 1 108 ILE 108 650  650  ILE ILE AAZA . n 
A 1 109 PRO 109 651  651  PRO PRO AAZA . n 
A 1 110 GLU 110 652  652  GLU GLU AAZA . n 
A 1 111 PRO 111 653  653  PRO PRO AAZA . n 
A 1 112 GLU 112 654  ?    ?   ?   AAZA . n 
A 1 113 PRO 113 655  ?    ?   ?   AAZA . n 
A 1 114 THR 114 656  ?    ?   ?   AAZA . n 
A 1 115 GLU 115 657  ?    ?   ?   AAZA . n 
A 1 116 ALA 116 658  ?    ?   ?   AAZA . n 
A 1 117 ASP 117 659  ?    ?   ?   AAZA . n 
A 1 118 ARG 118 660  ?    ?   ?   AAZA . n 
A 1 119 ILE 119 661  ?    ?   ?   AAZA . n 
A 1 120 ALA 120 662  ?    ?   ?   AAZA . n 
A 1 121 ILE 121 663  ?    ?   ?   AAZA . n 
A 1 122 GLU 122 664  ?    ?   ?   AAZA . n 
A 1 123 ASN 123 665  ?    ?   ?   AAZA . n 
A 1 124 GLY 124 666  ?    ?   ?   AAZA . n 
A 1 125 ASP 125 667  ?    ?   ?   AAZA . n 
A 1 126 GLN 126 668  ?    ?   ?   AAZA . n 
A 1 127 PRO 127 669  ?    ?   ?   AAZA . n 
A 1 128 LEU 128 670  ?    ?   ?   AAZA . n 
A 1 129 SER 129 671  671  SER SER AAZA . n 
A 1 130 ALA 130 672  672  ALA ALA AAZA . n 
A 1 131 GLU 131 673  673  GLU GLU AAZA . n 
A 1 132 LEU 132 674  674  LEU LEU AAZA . n 
A 1 133 LYS 133 675  675  LYS LYS AAZA . n 
A 1 134 ARG 134 676  676  ARG ARG AAZA . n 
A 1 135 PHE 135 677  677  PHE PHE AAZA . n 
A 1 136 ARG 136 678  678  ARG ARG AAZA . n 
A 1 137 LYS 137 679  679  LYS LYS AAZA . n 
A 1 138 GLU 138 680  680  GLU GLU AAZA . n 
A 1 139 TYR 139 681  681  TYR TYR AAZA . n 
A 1 140 ILE 140 682  682  ILE ILE AAZA . n 
A 1 141 GLN 141 683  683  GLN GLN AAZA . n 
A 1 142 PRO 142 684  684  PRO PRO AAZA . n 
A 1 143 VAL 143 685  685  VAL VAL AAZA . n 
A 1 144 GLN 144 686  686  GLN GLN AAZA . n 
A 1 145 LEU 145 687  687  LEU LEU AAZA . n 
A 1 146 ARG 146 688  688  ARG ARG AAZA . n 
A 1 147 VAL 147 689  689  VAL VAL AAZA . n 
A 1 148 LEU 148 690  690  LEU LEU AAZA . n 
A 1 149 ASN 149 691  691  ASN ASN AAZA . n 
A 1 150 VAL 150 692  692  VAL VAL AAZA . n 
A 1 151 CYS 151 693  693  CYS CYS AAZA . n 
A 1 152 ARG 152 694  694  ARG ARG AAZA . n 
A 1 153 HIS 153 695  695  HIS HIS AAZA . n 
A 1 154 TRP 154 696  696  TRP TRP AAZA . n 
A 1 155 VAL 155 697  697  VAL VAL AAZA . n 
A 1 156 GLU 156 698  698  GLU GLU AAZA . n 
A 1 157 HIS 157 699  699  HIS HIS AAZA . n 
A 1 158 HIS 158 700  700  HIS HIS AAZA . n 
A 1 159 PHE 159 701  701  PHE PHE AAZA . n 
A 1 160 TYR 160 702  702  TYR TYR AAZA . n 
A 1 161 ASP 161 703  703  ASP ASP AAZA . n 
A 1 162 PHE 162 704  704  PHE PHE AAZA . n 
A 1 163 GLU 163 705  705  GLU GLU AAZA . n 
A 1 164 ARG 164 706  706  ARG ARG AAZA . n 
A 1 165 ASP 165 707  707  ASP ASP AAZA . n 
A 1 166 ALA 166 708  708  ALA ALA AAZA . n 
A 1 167 TYR 167 709  709  TYR TYR AAZA . n 
A 1 168 LEU 168 710  710  LEU LEU AAZA . n 
A 1 169 LEU 169 711  711  LEU LEU AAZA . n 
A 1 170 GLN 170 712  712  GLN GLN AAZA . n 
A 1 171 ARG 171 713  713  ARG ARG AAZA . n 
A 1 172 MET 172 714  714  MET MET AAZA . n 
A 1 173 GLU 173 715  715  GLU GLU AAZA . n 
A 1 174 GLU 174 716  716  GLU GLU AAZA . n 
A 1 175 PHE 175 717  717  PHE PHE AAZA . n 
A 1 176 ILE 176 718  718  ILE ILE AAZA . n 
A 1 177 GLY 177 719  719  GLY GLY AAZA . n 
A 1 178 THR 178 720  720  THR THR AAZA . n 
A 1 179 VAL 179 721  721  VAL VAL AAZA . n 
A 1 180 ARG 180 722  722  ARG ARG AAZA . n 
A 1 181 GLY 181 723  723  GLY GLY AAZA . n 
A 1 182 LYS 182 724  724  LYS LYS AAZA . n 
A 1 183 ALA 183 725  725  ALA ALA AAZA . n 
A 1 184 MET 184 726  726  MET MET AAZA . n 
A 1 185 LYS 185 727  727  LYS LYS AAZA . n 
A 1 186 LYS 186 728  728  LYS LYS AAZA . n 
A 1 187 TRP 187 729  729  TRP TRP AAZA . n 
A 1 188 VAL 188 730  730  VAL VAL AAZA . n 
A 1 189 GLU 189 731  731  GLU GLU AAZA . n 
A 1 190 SER 190 732  732  SER SER AAZA . n 
A 1 191 ILE 191 733  733  ILE ILE AAZA . n 
A 1 192 THR 192 734  734  THR THR AAZA . n 
A 1 193 LYS 193 735  735  LYS LYS AAZA . n 
A 1 194 ILE 194 736  736  ILE ILE AAZA . n 
A 1 195 ILE 195 737  737  ILE ILE AAZA . n 
A 1 196 GLN 196 738  738  GLN GLN AAZA . n 
A 1 197 ARG 197 739  739  ARG ARG AAZA . n 
A 1 198 LYS 198 740  740  LYS LYS AAZA . n 
A 1 199 LYS 199 741  741  LYS LYS AAZA . n 
A 1 200 ILE 200 742  742  ILE ILE AAZA . n 
A 1 201 ALA 201 743  743  ALA ALA AAZA . n 
A 1 202 ARG 202 744  ?    ?   ?   AAZA . n 
A 1 203 ASP 203 745  ?    ?   ?   AAZA . n 
A 1 204 ASN 204 746  ?    ?   ?   AAZA . n 
A 1 205 GLY 205 747  ?    ?   ?   AAZA . n 
A 1 206 PRO 206 748  ?    ?   ?   AAZA . n 
A 1 207 GLY 207 749  ?    ?   ?   AAZA . n 
A 1 208 HIS 208 750  ?    ?   ?   AAZA . n 
A 1 209 ASN 209 751  ?    ?   ?   AAZA . n 
A 1 210 ILE 210 752  752  ILE ILE AAZA . n 
A 1 211 THR 211 753  753  THR THR AAZA . n 
A 1 212 PHE 212 754  754  PHE PHE AAZA . n 
A 1 213 GLN 213 755  755  GLN GLN AAZA . n 
A 1 214 SER 214 756  756  SER SER AAZA . n 
A 1 215 SER 215 757  757  SER SER AAZA . n 
A 1 216 PRO 216 758  758  PRO PRO AAZA . n 
A 1 217 PRO 217 759  759  PRO PRO AAZA . n 
A 1 218 THR 218 760  760  THR THR AAZA . n 
A 1 219 VAL 219 761  761  VAL VAL AAZA . n 
A 1 220 GLU 220 762  762  GLU GLU AAZA . n 
A 1 221 TRP 221 763  763  TRP TRP AAZA . n 
A 1 222 HIS 222 764  764  HIS HIS AAZA . n 
A 1 223 ILE 223 765  765  ILE ILE AAZA . n 
A 1 224 SER 224 766  766  SER SER AAZA . n 
A 1 225 ARG 225 767  767  ARG ARG AAZA . n 
A 1 226 PRO 226 768  768  PRO PRO AAZA . n 
A 1 227 GLY 227 769  769  GLY GLY AAZA . n 
A 1 228 HIS 228 770  770  HIS HIS AAZA . n 
A 1 229 ILE 229 771  771  ILE ILE AAZA . n 
A 1 230 GLU 230 772  772  GLU GLU AAZA . n 
A 1 231 THR 231 773  773  THR THR AAZA . n 
A 1 232 PHE 232 774  774  PHE PHE AAZA . n 
A 1 233 ASP 233 775  775  ASP ASP AAZA . n 
A 1 234 LEU 234 776  776  LEU LEU AAZA . n 
A 1 235 LEU 235 777  777  LEU LEU AAZA . n 
A 1 236 THR 236 778  778  THR THR AAZA . n 
A 1 237 LEU 237 779  779  LEU LEU AAZA . n 
A 1 238 HIS 238 780  780  HIS HIS AAZA . n 
A 1 239 PRO 239 781  781  PRO PRO AAZA . n 
A 1 240 ILE 240 782  782  ILE ILE AAZA . n 
A 1 241 GLU 241 783  783  GLU GLU AAZA . n 
A 1 242 ILE 242 784  784  ILE ILE AAZA . n 
A 1 243 ALA 243 785  785  ALA ALA AAZA . n 
A 1 244 ARG 244 786  786  ARG ARG AAZA . n 
A 1 245 GLN 245 787  787  GLN GLN AAZA . n 
A 1 246 LEU 246 788  788  LEU LEU AAZA . n 
A 1 247 THR 247 789  789  THR THR AAZA . n 
A 1 248 LEU 248 790  790  LEU LEU AAZA . n 
A 1 249 LEU 249 791  791  LEU LEU AAZA . n 
A 1 250 GLU 250 792  792  GLU GLU AAZA . n 
A 1 251 SER 251 793  793  SER SER AAZA . n 
A 1 252 ASP 252 794  794  ASP ASP AAZA . n 
A 1 253 LEU 253 795  795  LEU LEU AAZA . n 
A 1 254 TYR 254 796  796  TYR TYR AAZA . n 
A 1 255 ARG 255 797  797  ARG ARG AAZA . n 
A 1 256 ALA 256 798  798  ALA ALA AAZA . n 
A 1 257 VAL 257 799  799  VAL VAL AAZA . n 
A 1 258 GLN 258 800  800  GLN GLN AAZA . n 
A 1 259 PRO 259 801  801  PRO PRO AAZA . n 
A 1 260 SER 260 802  802  SER SER AAZA . n 
A 1 261 GLU 261 803  803  GLU GLU AAZA . n 
A 1 262 LEU 262 804  804  LEU LEU AAZA . n 
A 1 263 VAL 263 805  805  VAL VAL AAZA . n 
A 1 264 GLY 264 806  806  GLY GLY AAZA . n 
A 1 265 SER 265 807  807  SER SER AAZA . n 
A 1 266 VAL 266 808  808  VAL VAL AAZA . n 
A 1 267 TRP 267 809  809  TRP TRP AAZA . n 
A 1 268 THR 268 810  810  THR THR AAZA . n 
A 1 269 LYS 269 811  811  LYS LYS AAZA . n 
A 1 270 GLU 270 812  812  GLU GLU AAZA . n 
A 1 271 ASP 271 813  813  ASP ASP AAZA . n 
A 1 272 LYS 272 814  814  LYS LYS AAZA . n 
A 1 273 GLU 273 815  815  GLU GLU AAZA . n 
A 1 274 ILE 274 816  816  ILE ILE AAZA . n 
A 1 275 ASN 275 817  817  ASN ASN AAZA . n 
A 1 276 SER 276 818  818  SER SER AAZA . n 
A 1 277 PRO 277 819  819  PRO PRO AAZA . n 
A 1 278 ASN 278 820  820  ASN ASN AAZA . n 
A 1 279 LEU 279 821  821  LEU LEU AAZA . n 
A 1 280 LEU 280 822  822  LEU LEU AAZA . n 
A 1 281 LYS 281 823  823  LYS LYS AAZA . n 
A 1 282 MET 282 824  824  MET MET AAZA . n 
A 1 283 ILE 283 825  825  ILE ILE AAZA . n 
A 1 284 ARG 284 826  826  ARG ARG AAZA . n 
A 1 285 HIS 285 827  827  HIS HIS AAZA . n 
A 1 286 THR 286 828  828  THR THR AAZA . n 
A 1 287 THR 287 829  829  THR THR AAZA . n 
A 1 288 ASN 288 830  830  ASN ASN AAZA . n 
A 1 289 LEU 289 831  831  LEU LEU AAZA . n 
A 1 290 THR 290 832  832  THR THR AAZA . n 
A 1 291 LEU 291 833  833  LEU LEU AAZA . n 
A 1 292 TRP 292 834  834  TRP TRP AAZA . n 
A 1 293 PHE 293 835  835  PHE PHE AAZA . n 
A 1 294 GLU 294 836  836  GLU GLU AAZA . n 
A 1 295 LYS 295 837  837  LYS LYS AAZA . n 
A 1 296 CYS 296 838  838  CYS CYS AAZA . n 
A 1 297 ILE 297 839  839  ILE ILE AAZA . n 
A 1 298 VAL 298 840  840  VAL VAL AAZA . n 
A 1 299 GLU 299 841  841  GLU GLU AAZA . n 
A 1 300 THR 300 842  842  THR THR AAZA . n 
A 1 301 GLU 301 843  843  GLU GLU AAZA . n 
A 1 302 ASN 302 844  844  ASN ASN AAZA . n 
A 1 303 LEU 303 845  845  LEU LEU AAZA . n 
A 1 304 GLU 304 846  846  GLU GLU AAZA . n 
A 1 305 GLU 305 847  847  GLU GLU AAZA . n 
A 1 306 ARG 306 848  848  ARG ARG AAZA . n 
A 1 307 VAL 307 849  849  VAL VAL AAZA . n 
A 1 308 ALA 308 850  850  ALA ALA AAZA . n 
A 1 309 VAL 309 851  851  VAL VAL AAZA . n 
A 1 310 VAL 310 852  852  VAL VAL AAZA . n 
A 1 311 SER 311 853  853  SER SER AAZA . n 
A 1 312 ARG 312 854  854  ARG ARG AAZA . n 
A 1 313 ILE 313 855  855  ILE ILE AAZA . n 
A 1 314 ILE 314 856  856  ILE ILE AAZA . n 
A 1 315 GLU 315 857  857  GLU GLU AAZA . n 
A 1 316 ILE 316 858  858  ILE ILE AAZA . n 
A 1 317 LEU 317 859  859  LEU LEU AAZA . n 
A 1 318 GLN 318 860  860  GLN GLN AAZA . n 
A 1 319 VAL 319 861  861  VAL VAL AAZA . n 
A 1 320 PHE 320 862  862  PHE PHE AAZA . n 
A 1 321 GLN 321 863  863  GLN GLN AAZA . n 
A 1 322 GLU 322 864  864  GLU GLU AAZA . n 
A 1 323 LEU 323 865  865  LEU LEU AAZA . n 
A 1 324 ASN 324 866  866  ASN ASN AAZA . n 
A 1 325 ASN 325 867  867  ASN ASN AAZA . n 
A 1 326 PHE 326 868  868  PHE PHE AAZA . n 
A 1 327 ASN 327 869  869  ASN ASN AAZA . n 
A 1 328 GLY 328 870  870  GLY GLY AAZA . n 
A 1 329 VAL 329 871  871  VAL VAL AAZA . n 
A 1 330 LEU 330 872  872  LEU LEU AAZA . n 
A 1 331 GLU 331 873  873  GLU GLU AAZA . n 
A 1 332 VAL 332 874  874  VAL VAL AAZA . n 
A 1 333 VAL 333 875  875  VAL VAL AAZA . n 
A 1 334 SER 334 876  876  SER SER AAZA . n 
A 1 335 ALA 335 877  877  ALA ALA AAZA . n 
A 1 336 MET 336 878  878  MET MET AAZA . n 
A 1 337 ASN 337 879  879  ASN ASN AAZA . n 
A 1 338 SER 338 880  880  SER SER AAZA . n 
A 1 339 SER 339 881  881  SER SER AAZA . n 
A 1 340 PRO 340 882  882  PRO PRO AAZA . n 
A 1 341 VAL 341 883  883  VAL VAL AAZA . n 
A 1 342 TYR 342 884  884  TYR TYR AAZA . n 
A 1 343 ARG 343 885  885  ARG ARG AAZA . n 
A 1 344 LEU 344 886  886  LEU LEU AAZA . n 
A 1 345 ASP 345 887  887  ASP ASP AAZA . n 
A 1 346 HIS 346 888  888  HIS HIS AAZA . n 
A 1 347 THR 347 889  889  THR THR AAZA . n 
A 1 348 PHE 348 890  890  PHE PHE AAZA . n 
A 1 349 GLU 349 891  891  GLU GLU AAZA . n 
A 1 350 GLN 350 892  892  GLN GLN AAZA . n 
A 1 351 ILE 351 893  893  ILE ILE AAZA . n 
A 1 352 PRO 352 894  894  PRO PRO AAZA . n 
A 1 353 SER 353 895  895  SER SER AAZA . n 
A 1 354 ARG 354 896  896  ARG ARG AAZA . n 
A 1 355 GLN 355 897  897  GLN GLN AAZA . n 
A 1 356 LYS 356 898  898  LYS LYS AAZA . n 
A 1 357 LYS 357 899  899  LYS LYS AAZA . n 
A 1 358 ILE 358 900  900  ILE ILE AAZA . n 
A 1 359 LEU 359 901  901  LEU LEU AAZA . n 
A 1 360 GLU 360 902  902  GLU GLU AAZA . n 
A 1 361 GLU 361 903  903  GLU GLU AAZA . n 
A 1 362 ALA 362 904  904  ALA ALA AAZA . n 
A 1 363 HIS 363 905  905  HIS HIS AAZA . n 
A 1 364 GLU 364 906  906  GLU GLU AAZA . n 
A 1 365 LEU 365 907  907  LEU LEU AAZA . n 
A 1 366 SER 366 908  908  SER SER AAZA . n 
A 1 367 GLU 367 909  909  GLU GLU AAZA . n 
A 1 368 ASP 368 910  910  ASP ASP AAZA . n 
A 1 369 HIS 369 911  911  HIS HIS AAZA . n 
A 1 370 TYR 370 912  912  TYR TYR AAZA . n 
A 1 371 LYS 371 913  913  LYS LYS AAZA . n 
A 1 372 LYS 372 914  914  LYS LYS AAZA . n 
A 1 373 TYR 373 915  915  TYR TYR AAZA . n 
A 1 374 LEU 374 916  916  LEU LEU AAZA . n 
A 1 375 ALA 375 917  917  ALA ALA AAZA . n 
A 1 376 LYS 376 918  918  LYS LYS AAZA . n 
A 1 377 LEU 377 919  919  LEU LEU AAZA . n 
A 1 378 ARG 378 920  920  ARG ARG AAZA . n 
A 1 379 SER 379 921  921  SER SER AAZA . n 
A 1 380 ILE 380 922  922  ILE ILE AAZA . n 
A 1 381 ASN 381 923  923  ASN ASN AAZA . n 
A 1 382 PRO 382 924  924  PRO PRO AAZA . n 
A 1 383 PRO 383 925  925  PRO PRO AAZA . n 
A 1 384 CYS 384 926  926  CYS CYS AAZA . n 
A 1 385 VAL 385 927  927  VAL VAL AAZA . n 
A 1 386 PRO 386 928  928  PRO PRO AAZA . n 
A 1 387 PHE 387 929  929  PHE PHE AAZA . n 
A 1 388 PHE 388 930  930  PHE PHE AAZA . n 
A 1 389 GLY 389 931  931  GLY GLY AAZA . n 
A 1 390 ILE 390 932  932  ILE ILE AAZA . n 
A 1 391 TYR 391 933  933  TYR TYR AAZA . n 
A 1 392 LEU 392 934  934  LEU LEU AAZA . n 
A 1 393 THR 393 935  935  THR THR AAZA . n 
A 1 394 ASN 394 936  936  ASN ASN AAZA . n 
A 1 395 ILE 395 937  937  ILE ILE AAZA . n 
A 1 396 LEU 396 938  938  LEU LEU AAZA . n 
A 1 397 LYS 397 939  939  LYS LYS AAZA . n 
A 1 398 THR 398 940  940  THR THR AAZA . n 
A 1 399 GLU 399 941  941  GLU GLU AAZA . n 
A 1 400 GLU 400 942  942  GLU GLU AAZA . n 
A 1 401 GLY 401 943  943  GLY GLY AAZA . n 
A 1 402 ASN 402 944  944  ASN ASN AAZA . n 
A 1 403 PRO 403 945  945  PRO PRO AAZA . n 
A 1 404 GLU 404 946  946  GLU GLU AAZA . n 
A 1 405 VAL 405 947  947  VAL VAL AAZA . n 
A 1 406 LEU 406 948  948  LEU LEU AAZA . n 
A 1 407 LYS 407 949  949  LYS LYS AAZA . n 
A 1 408 ARG 408 950  950  ARG ARG AAZA . n 
A 1 409 HIS 409 951  951  HIS HIS AAZA . n 
A 1 410 GLY 410 952  952  GLY GLY AAZA . n 
A 1 411 LYS 411 953  953  LYS LYS AAZA . n 
A 1 412 GLU 412 954  954  GLU GLU AAZA . n 
A 1 413 LEU 413 955  955  LEU LEU AAZA . n 
A 1 414 ILE 414 956  956  ILE ILE AAZA . n 
A 1 415 ASN 415 957  957  ASN ASN AAZA . n 
A 1 416 PHE 416 958  958  PHE PHE AAZA . n 
A 1 417 SER 417 959  959  SER SER AAZA . n 
A 1 418 LYS 418 960  960  LYS LYS AAZA . n 
A 1 419 ARG 419 961  961  ARG ARG AAZA . n 
A 1 420 ARG 420 962  962  ARG ARG AAZA . n 
A 1 421 LYS 421 963  963  LYS LYS AAZA . n 
A 1 422 VAL 422 964  964  VAL VAL AAZA . n 
A 1 423 ALA 423 965  965  ALA ALA AAZA . n 
A 1 424 GLU 424 966  966  GLU GLU AAZA . n 
A 1 425 ILE 425 967  967  ILE ILE AAZA . n 
A 1 426 THR 426 968  968  THR THR AAZA . n 
A 1 427 GLY 427 969  969  GLY GLY AAZA . n 
A 1 428 GLU 428 970  970  GLU GLU AAZA . n 
A 1 429 ILE 429 971  971  ILE ILE AAZA . n 
A 1 430 GLN 430 972  972  GLN GLN AAZA . n 
A 1 431 GLN 431 973  973  GLN GLN AAZA . n 
A 1 432 TYR 432 974  974  TYR TYR AAZA . n 
A 1 433 GLN 433 975  975  GLN GLN AAZA . n 
A 1 434 ASN 434 976  976  ASN ASN AAZA . n 
A 1 435 GLN 435 977  977  GLN GLN AAZA . n 
A 1 436 PRO 436 978  978  PRO PRO AAZA . n 
A 1 437 TYR 437 979  979  TYR TYR AAZA . n 
A 1 438 CYS 438 980  980  CYS CYS AAZA . n 
A 1 439 LEU 439 981  981  LEU LEU AAZA . n 
A 1 440 ARG 440 982  982  ARG ARG AAZA . n 
A 1 441 VAL 441 983  983  VAL VAL AAZA . n 
A 1 442 GLU 442 984  984  GLU GLU AAZA . n 
A 1 443 SER 443 985  985  SER SER AAZA . n 
A 1 444 ASP 444 986  986  ASP ASP AAZA . n 
A 1 445 ILE 445 987  987  ILE ILE AAZA . n 
A 1 446 LYS 446 988  988  LYS LYS AAZA . n 
A 1 447 ARG 447 989  989  ARG ARG AAZA . n 
A 1 448 PHE 448 990  990  PHE PHE AAZA . n 
A 1 449 PHE 449 991  991  PHE PHE AAZA . n 
A 1 450 GLU 450 992  992  GLU GLU AAZA . n 
A 1 451 ASN 451 993  993  ASN ASN AAZA . n 
A 1 452 LEU 452 994  994  LEU LEU AAZA . n 
A 1 453 ASN 453 995  995  ASN ASN AAZA . n 
A 1 454 PRO 454 996  996  PRO PRO AAZA . n 
A 1 455 MET 455 997  997  MET MET AAZA . n 
A 1 456 GLY 456 998  998  GLY GLY AAZA . n 
A 1 457 ASN 457 999  999  ASN ASN AAZA . n 
A 1 458 SER 458 1000 1000 SER SER AAZA . n 
A 1 459 MET 459 1001 1001 MET MET AAZA . n 
A 1 460 GLU 460 1002 1002 GLU GLU AAZA . n 
A 1 461 LYS 461 1003 1003 LYS LYS AAZA . n 
A 1 462 GLU 462 1004 1004 GLU GLU AAZA . n 
A 1 463 PHE 463 1005 1005 PHE PHE AAZA . n 
A 1 464 THR 464 1006 1006 THR THR AAZA . n 
A 1 465 ASP 465 1007 1007 ASP ASP AAZA . n 
A 1 466 TYR 466 1008 1008 TYR TYR AAZA . n 
A 1 467 LEU 467 1009 1009 LEU LEU AAZA . n 
A 1 468 PHE 468 1010 1010 PHE PHE AAZA . n 
A 1 469 ASN 469 1011 1011 ASN ASN AAZA . n 
A 1 470 LYS 470 1012 1012 LYS LYS AAZA . n 
A 1 471 SER 471 1013 1013 SER SER AAZA . n 
A 1 472 LEU 472 1014 1014 LEU LEU AAZA . n 
A 1 473 GLU 473 1015 1015 GLU GLU AAZA . n 
A 1 474 ILE 474 1016 1016 ILE ILE AAZA . n 
A 1 475 GLU 475 1017 1017 GLU GLU AAZA . n 
A 1 476 PRO 476 1018 1018 PRO PRO AAZA . n 
A 1 477 ARG 477 1019 1019 ARG ARG AAZA . n 
A 1 478 ASN 478 1020 1020 ASN ASN AAZA . n 
A 1 479 PRO 479 1021 1021 PRO PRO AAZA . n 
A 1 480 LYS 480 1022 1022 LYS LYS AAZA . n 
A 1 481 PRO 481 1023 1023 PRO PRO AAZA . n 
A 1 482 LEU 482 1024 1024 LEU LEU AAZA . n 
A 1 483 PRO 483 1025 1025 PRO PRO AAZA . n 
A 1 484 ARG 484 1026 1026 ARG ARG AAZA . n 
A 1 485 PHE 485 1027 1027 PHE PHE AAZA . n 
A 1 486 PRO 486 1028 1028 PRO PRO AAZA . n 
A 1 487 LYS 487 1029 1029 LYS LYS AAZA . n 
A 1 488 LYS 488 1030 1030 LYS LYS AAZA . n 
A 1 489 TYR 489 1031 1031 TYR TYR AAZA . n 
A 1 490 SER 490 1032 1032 SER SER AAZA . n 
A 1 491 TYR 491 1033 1033 TYR TYR AAZA . n 
A 1 492 PRO 492 1034 1034 PRO PRO AAZA . n 
A 1 493 LEU 493 1035 1035 LEU LEU AAZA . n 
A 1 494 LYS 494 1036 1036 LYS LYS AAZA . n 
A 1 495 SER 495 1037 1037 SER SER AAZA . n 
A 1 496 PRO 496 1038 1038 PRO PRO AAZA . n 
A 1 497 GLY 497 1039 1039 GLY GLY AAZA . n 
A 1 498 VAL 498 1040 1040 VAL VAL AAZA . n 
A 1 499 ARG 499 1041 1041 ARG ARG AAZA . n 
A 1 500 PRO 500 1042 1042 PRO PRO AAZA . n 
A 1 501 SER 501 1043 1043 SER SER AAZA . n 
A 1 502 ASN 502 1044 ?    ?   ?   AAZA . n 
A 1 503 PRO 503 1045 ?    ?   ?   AAZA . n 
A 1 504 ARG 504 1046 ?    ?   ?   AAZA . n 
A 1 505 PRO 505 1047 ?    ?   ?   AAZA . n 
A 1 506 GLY 506 1048 ?    ?   ?   AAZA . n 
A 1 507 THR 507 1049 ?    ?   ?   AAZA . n 
B 2 1   GLN 1   1    ?    ?   ?   C    . n 
B 2 2   VAL 2   2    2    VAL VAL C    . n 
B 2 3   GLN 3   3    3    GLN GLN C    . n 
B 2 4   LEU 4   4    4    LEU LEU C    . n 
B 2 5   VAL 5   5    5    VAL VAL C    . n 
B 2 6   GLU 6   6    6    GLU GLU C    . n 
B 2 7   SER 7   7    7    SER SER C    . n 
B 2 8   GLY 8   8    8    GLY GLY C    . n 
B 2 9   GLY 9   9    9    GLY GLY C    . n 
B 2 10  GLY 10  10   10   GLY GLY C    . n 
B 2 11  LEU 11  11   ?    ?   ?   C    . n 
B 2 12  VAL 12  12   ?    ?   ?   C    . n 
B 2 13  GLN 13  13   ?    ?   ?   C    . n 
B 2 14  ALA 14  14   ?    ?   ?   C    . n 
B 2 15  GLY 15  15   ?    ?   ?   C    . n 
B 2 16  GLY 16  16   ?    ?   ?   C    . n 
B 2 17  SER 17  17   ?    ?   ?   C    . n 
B 2 18  LEU 18  18   ?    ?   ?   C    . n 
B 2 19  ARG 19  19   19   ARG ARG C    . n 
B 2 20  LEU 20  20   20   LEU LEU C    . n 
B 2 21  SER 21  21   21   SER SER C    . n 
B 2 22  CYS 22  22   22   CYS CYS C    . n 
B 2 23  ALA 23  23   23   ALA ALA C    . n 
B 2 24  ALA 24  24   24   ALA ALA C    . n 
B 2 25  SER 25  25   25   SER SER C    . n 
B 2 26  GLY 26  26   26   GLY GLY C    . n 
B 2 27  ASN 27  27   ?    ?   ?   C    . n 
B 2 28  ILE 28  28   28   ILE ILE C    . n 
B 2 29  LEU 29  29   29   LEU LEU C    . n 
B 2 30  PRO 30  30   30   PRO PRO C    . n 
B 2 31  ILE 31  31   31   ILE ILE C    . n 
B 2 32  ASN 32  32   32   ASN ASN C    . n 
B 2 33  VAL 33  33   33   VAL VAL C    . n 
B 2 34  MET 34  34   34   MET MET C    . n 
B 2 35  GLY 35  35   35   GLY GLY C    . n 
B 2 36  TRP 36  36   36   TRP TRP C    . n 
B 2 37  TYR 37  37   37   TYR TYR C    . n 
B 2 38  ARG 38  38   38   ARG ARG C    . n 
B 2 39  GLN 39  39   ?    ?   ?   C    . n 
B 2 40  THR 40  40   ?    ?   ?   C    . n 
B 2 41  PRO 41  41   ?    ?   ?   C    . n 
B 2 42  GLY 42  42   ?    ?   ?   C    . n 
B 2 43  SER 43  43   43   SER SER C    . n 
B 2 44  GLN 44  44   44   GLN GLN C    . n 
B 2 45  ARG 45  45   45   ARG ARG C    . n 
B 2 46  GLU 46  46   46   GLU GLU C    . n 
B 2 47  LEU 47  47   47   LEU LEU C    . n 
B 2 48  VAL 48  48   48   VAL VAL C    . n 
B 2 49  ALA 49  49   49   ALA ALA C    . n 
B 2 50  THR 50  50   50   THR THR C    . n 
B 2 51  ILE 51  51   51   ILE ILE C    . n 
B 2 52  VAL 52  52   52   VAL VAL C    . n 
B 2 53  THR 53  53   53   THR THR C    . n 
B 2 54  SER 54  54   54   SER SER C    . n 
B 2 55  GLY 55  55   55   GLY GLY C    . n 
B 2 56  GLY 56  56   56   GLY GLY C    . n 
B 2 57  SER 57  57   57   SER SER C    . n 
B 2 58  THR 58  58   58   THR THR C    . n 
B 2 59  ALA 59  59   59   ALA ALA C    . n 
B 2 60  GLY 60  60   60   GLY GLY C    . n 
B 2 61  ASN 61  61   61   ASN ASN C    . n 
B 2 62  THR 62  62   62   THR THR C    . n 
B 2 63  ASN 63  63   63   ASN ASN C    . n 
B 2 64  TYR 64  64   64   TYR TYR C    . n 
B 2 65  VAL 65  65   65   VAL VAL C    . n 
B 2 66  ASP 66  66   66   ASP ASP C    . n 
B 2 67  SER 67  67   67   SER SER C    . n 
B 2 68  VAL 68  68   ?    ?   ?   C    . n 
B 2 69  LYS 69  69   ?    ?   ?   C    . n 
B 2 70  GLY 70  70   ?    ?   ?   C    . n 
B 2 71  ARG 71  71   ?    ?   ?   C    . n 
B 2 72  PHE 72  72   ?    ?   ?   C    . n 
B 2 73  THR 73  73   ?    ?   ?   C    . n 
B 2 74  ILE 74  74   ?    ?   ?   C    . n 
B 2 75  SER 75  75   ?    ?   ?   C    . n 
B 2 76  GLY 76  76   ?    ?   ?   C    . n 
B 2 77  ASP 77  77   ?    ?   ?   C    . n 
B 2 78  ASN 78  78   ?    ?   ?   C    . n 
B 2 79  ALA 79  79   ?    ?   ?   C    . n 
B 2 80  LYS 80  80   ?    ?   ?   C    . n 
B 2 81  ASN 81  81   ?    ?   ?   C    . n 
B 2 82  THR 82  82   ?    ?   ?   C    . n 
B 2 83  VAL 83  83   ?    ?   ?   C    . n 
B 2 84  TYR 84  84   ?    ?   ?   C    . n 
B 2 85  LEU 85  85   ?    ?   ?   C    . n 
B 2 86  GLN 86  86   ?    ?   ?   C    . n 
B 2 87  MET 87  87   ?    ?   ?   C    . n 
B 2 88  SER 88  88   ?    ?   ?   C    . n 
B 2 89  SER 89  89   ?    ?   ?   C    . n 
B 2 90  LEU 90  90   ?    ?   ?   C    . n 
B 2 91  LYS 91  91   ?    ?   ?   C    . n 
B 2 92  PRO 92  92   ?    ?   ?   C    . n 
B 2 93  GLU 93  93   ?    ?   ?   C    . n 
B 2 94  ASP 94  94   ?    ?   ?   C    . n 
B 2 95  THR 95  95   ?    ?   ?   C    . n 
B 2 96  ALA 96  96   96   ALA ALA C    . n 
B 2 97  VAL 97  97   97   VAL VAL C    . n 
B 2 98  TYR 98  98   98   TYR TYR C    . n 
B 2 99  TYR 99  99   99   TYR TYR C    . n 
B 2 100 CYS 100 100  100  CYS CYS C    . n 
B 2 101 ASN 101 101  101  ASN ASN C    . n 
B 2 102 LEU 102 102  102  LEU LEU C    . n 
B 2 103 LYS 103 103  103  LYS LYS C    . n 
B 2 104 THR 104 104  104  THR THR C    . n 
B 2 105 ARG 105 105  105  ARG ARG C    . n 
B 2 106 ARG 106 106  106  ARG ARG C    . n 
B 2 107 ALA 107 107  107  ALA ALA C    . n 
B 2 108 PRO 108 108  108  PRO PRO C    . n 
B 2 109 TRP 109 109  109  TRP TRP C    . n 
B 2 110 ALA 110 110  110  ALA ALA C    . n 
B 2 111 THR 111 111  111  THR THR C    . n 
B 2 112 PRO 112 112  112  PRO PRO C    . n 
B 2 113 ASN 113 113  113  ASN ASN C    . n 
B 2 114 ASN 114 114  114  ASN ASN C    . n 
B 2 115 TYR 115 115  115  TYR TYR C    . n 
B 2 116 TRP 116 116  116  TRP TRP C    . n 
B 2 117 GLY 117 117  117  GLY GLY C    . n 
B 2 118 GLN 118 118  118  GLN GLN C    . n 
B 2 119 GLY 119 119  119  GLY GLY C    . n 
B 2 120 THR 120 120  120  THR THR C    . n 
B 2 121 GLN 121 121  121  GLN GLN C    . n 
B 2 122 VAL 122 122  122  VAL VAL C    . n 
B 2 123 THR 123 123  123  THR THR C    . n 
B 2 124 VAL 124 124  ?    ?   ?   C    . n 
B 2 125 SER 125 125  ?    ?   ?   C    . n 
B 2 126 SER 126 126  ?    ?   ?   C    . n 
B 2 127 HIS 127 127  ?    ?   ?   C    . n 
B 2 128 HIS 128 128  ?    ?   ?   C    . n 
B 2 129 HIS 129 129  ?    ?   ?   C    . n 
B 2 130 HIS 130 130  ?    ?   ?   C    . n 
B 2 131 HIS 131 131  ?    ?   ?   C    . n 
B 2 132 HIS 132 132  ?    ?   ?   C    . n 
B 2 133 GLU 133 133  ?    ?   ?   C    . n 
B 2 134 PRO 134 134  ?    ?   ?   C    . n 
B 2 135 GLU 135 135  ?    ?   ?   C    . n 
B 2 136 ALA 136 136  ?    ?   ?   C    . n 
C 3 1   MET 1   -20  ?    ?   ?   R    . n 
C 3 2   GLY 2   -19  ?    ?   ?   R    . n 
C 3 3   SER 3   -18  ?    ?   ?   R    . n 
C 3 4   SER 4   -17  ?    ?   ?   R    . n 
C 3 5   HIS 5   -16  ?    ?   ?   R    . n 
C 3 6   HIS 6   -15  ?    ?   ?   R    . n 
C 3 7   HIS 7   -14  ?    ?   ?   R    . n 
C 3 8   HIS 8   -13  ?    ?   ?   R    . n 
C 3 9   HIS 9   -12  ?    ?   ?   R    . n 
C 3 10  HIS 10  -11  ?    ?   ?   R    . n 
C 3 11  SER 11  -10  ?    ?   ?   R    . n 
C 3 12  SER 12  -9   ?    ?   ?   R    . n 
C 3 13  GLY 13  -8   ?    ?   ?   R    . n 
C 3 14  GLU 14  -7   ?    ?   ?   R    . n 
C 3 15  ASN 15  -6   ?    ?   ?   R    . n 
C 3 16  LEU 16  -5   ?    ?   ?   R    . n 
C 3 17  TYR 17  -4   ?    ?   ?   R    . n 
C 3 18  PHE 18  -3   ?    ?   ?   R    . n 
C 3 19  GLN 19  -2   ?    ?   ?   R    . n 
C 3 20  GLY 20  -1   ?    ?   ?   R    . n 
C 3 21  SER 21  0    ?    ?   ?   R    . n 
C 3 22  MET 22  1    1    MET MET R    . n 
C 3 23  THR 23  2    2    THR THR R    . n 
C 3 24  GLU 24  3    3    GLU GLU R    . n 
C 3 25  TYR 25  4    4    TYR TYR R    . n 
C 3 26  LYS 26  5    5    LYS LYS R    . n 
C 3 27  LEU 27  6    6    LEU LEU R    . n 
C 3 28  VAL 28  7    7    VAL VAL R    . n 
C 3 29  VAL 29  8    8    VAL VAL R    . n 
C 3 30  VAL 30  9    9    VAL VAL R    . n 
C 3 31  GLY 31  10   10   GLY GLY R    . n 
C 3 32  ALA 32  11   11   ALA ALA R    . n 
C 3 33  VAL 33  12   12   VAL VAL R    . n 
C 3 34  GLY 34  13   13   GLY GLY R    . n 
C 3 35  VAL 35  14   14   VAL VAL R    . n 
C 3 36  GLY 36  15   15   GLY GLY R    . n 
C 3 37  LYS 37  16   16   LYS LYS R    . n 
C 3 38  SER 38  17   17   SER SER R    . n 
C 3 39  ALA 39  18   18   ALA ALA R    . n 
C 3 40  LEU 40  19   19   LEU LEU R    . n 
C 3 41  THR 41  20   20   THR THR R    . n 
C 3 42  ILE 42  21   21   ILE ILE R    . n 
C 3 43  GLN 43  22   22   GLN GLN R    . n 
C 3 44  LEU 44  23   23   LEU LEU R    . n 
C 3 45  ILE 45  24   24   ILE ILE R    . n 
C 3 46  GLN 46  25   25   GLN GLN R    . n 
C 3 47  ASN 47  26   ?    ?   ?   R    . n 
C 3 48  HIS 48  27   ?    ?   ?   R    . n 
C 3 49  PHE 49  28   ?    ?   ?   R    . n 
C 3 50  VAL 50  29   ?    ?   ?   R    . n 
C 3 51  ASP 51  30   ?    ?   ?   R    . n 
C 3 52  GLU 52  31   31   GLU GLU R    . n 
C 3 53  TYR 53  32   32   TYR TYR R    . n 
C 3 54  ASP 54  33   33   ASP ASP R    . n 
C 3 55  PRO 55  34   34   PRO PRO R    . n 
C 3 56  THR 56  35   35   THR THR R    . n 
C 3 57  ILE 57  36   36   ILE ILE R    . n 
C 3 58  GLU 58  37   37   GLU GLU R    . n 
C 3 59  ASP 59  38   38   ASP ASP R    . n 
C 3 60  SER 60  39   39   SER SER R    . n 
C 3 61  TYR 61  40   40   TYR TYR R    . n 
C 3 62  ARG 62  41   41   ARG ARG R    . n 
C 3 63  LYS 63  42   42   LYS LYS R    . n 
C 3 64  GLN 64  43   43   GLN GLN R    . n 
C 3 65  VAL 65  44   44   VAL VAL R    . n 
C 3 66  VAL 66  45   45   VAL VAL R    . n 
C 3 67  ILE 67  46   46   ILE ILE R    . n 
C 3 68  ASP 68  47   47   ASP ASP R    . n 
C 3 69  GLY 69  48   48   GLY GLY R    . n 
C 3 70  GLU 70  49   49   GLU GLU R    . n 
C 3 71  THR 71  50   50   THR THR R    . n 
C 3 72  CYS 72  51   51   CYS CYS R    . n 
C 3 73  LEU 73  52   52   LEU LEU R    . n 
C 3 74  LEU 74  53   53   LEU LEU R    . n 
C 3 75  ASP 75  54   54   ASP ASP R    . n 
C 3 76  ILE 76  55   55   ILE ILE R    . n 
C 3 77  LEU 77  56   56   LEU LEU R    . n 
C 3 78  ASP 78  57   57   ASP ASP R    . n 
C 3 79  THR 79  58   58   THR THR R    . n 
C 3 80  ALA 80  59   59   ALA ALA R    . n 
C 3 81  GLY 81  60   60   GLY GLY R    . n 
C 3 82  GLN 82  61   61   GLN GLN R    . n 
C 3 83  GLU 83  62   62   GLU GLU R    . n 
C 3 84  GLU 84  63   63   GLU GLU R    . n 
C 3 85  TYR 85  64   64   TYR TYR R    . n 
C 3 86  SER 86  65   65   SER SER R    . n 
C 3 87  ALA 87  66   66   ALA ALA R    . n 
C 3 88  MET 88  67   67   MET MET R    . n 
C 3 89  ARG 89  68   68   ARG ARG R    . n 
C 3 90  ASP 90  69   69   ASP ASP R    . n 
C 3 91  GLN 91  70   70   GLN GLN R    . n 
C 3 92  TYR 92  71   71   TYR TYR R    . n 
C 3 93  MET 93  72   72   MET MET R    . n 
C 3 94  ARG 94  73   73   ARG ARG R    . n 
C 3 95  THR 95  74   74   THR THR R    . n 
C 3 96  GLY 96  75   75   GLY GLY R    . n 
C 3 97  GLU 97  76   76   GLU GLU R    . n 
C 3 98  GLY 98  77   77   GLY GLY R    . n 
C 3 99  PHE 99  78   78   PHE PHE R    . n 
C 3 100 LEU 100 79   79   LEU LEU R    . n 
C 3 101 CYS 101 80   80   CYS CYS R    . n 
C 3 102 VAL 102 81   81   VAL VAL R    . n 
C 3 103 PHE 103 82   82   PHE PHE R    . n 
C 3 104 ALA 104 83   83   ALA ALA R    . n 
C 3 105 ILE 105 84   84   ILE ILE R    . n 
C 3 106 ASN 106 85   85   ASN ASN R    . n 
C 3 107 ASN 107 86   86   ASN ASN R    . n 
C 3 108 THR 108 87   87   THR THR R    . n 
C 3 109 LYS 109 88   88   LYS LYS R    . n 
C 3 110 SER 110 89   89   SER SER R    . n 
C 3 111 PHE 111 90   90   PHE PHE R    . n 
C 3 112 GLU 112 91   91   GLU GLU R    . n 
C 3 113 ASP 113 92   92   ASP ASP R    . n 
C 3 114 ILE 114 93   93   ILE ILE R    . n 
C 3 115 HIS 115 94   94   HIS HIS R    . n 
C 3 116 HIS 116 95   95   HIS HIS R    . n 
C 3 117 TYR 117 96   96   TYR TYR R    . n 
C 3 118 ARG 118 97   97   ARG ARG R    . n 
C 3 119 GLU 119 98   98   GLU GLU R    . n 
C 3 120 GLN 120 99   99   GLN GLN R    . n 
C 3 121 ILE 121 100  100  ILE ILE R    . n 
C 3 122 LYS 122 101  101  LYS LYS R    . n 
C 3 123 ARG 123 102  102  ARG ARG R    . n 
C 3 124 VAL 124 103  103  VAL VAL R    . n 
C 3 125 LYS 125 104  104  LYS LYS R    . n 
C 3 126 ASP 126 105  105  ASP ASP R    . n 
C 3 127 SER 127 106  106  SER SER R    . n 
C 3 128 GLU 128 107  107  GLU GLU R    . n 
C 3 129 ASP 129 108  108  ASP ASP R    . n 
C 3 130 VAL 130 109  109  VAL VAL R    . n 
C 3 131 PRO 131 110  110  PRO PRO R    . n 
C 3 132 MET 132 111  111  MET MET R    . n 
C 3 133 VAL 133 112  112  VAL VAL R    . n 
C 3 134 LEU 134 113  113  LEU LEU R    . n 
C 3 135 VAL 135 114  114  VAL VAL R    . n 
C 3 136 GLY 136 115  115  GLY GLY R    . n 
C 3 137 ASN 137 116  116  ASN ASN R    . n 
C 3 138 LYS 138 117  117  LYS LYS R    . n 
C 3 139 CYS 139 118  118  CYS CYS R    . n 
C 3 140 ASP 140 119  119  ASP ASP R    . n 
C 3 141 LEU 141 120  120  LEU LEU R    . n 
C 3 142 PRO 142 121  121  PRO PRO R    . n 
C 3 143 SER 143 122  122  SER SER R    . n 
C 3 144 ARG 144 123  123  ARG ARG R    . n 
C 3 145 THR 145 124  124  THR THR R    . n 
C 3 146 VAL 146 125  125  VAL VAL R    . n 
C 3 147 ASP 147 126  126  ASP ASP R    . n 
C 3 148 THR 148 127  127  THR THR R    . n 
C 3 149 LYS 149 128  128  LYS LYS R    . n 
C 3 150 GLN 150 129  129  GLN GLN R    . n 
C 3 151 ALA 151 130  130  ALA ALA R    . n 
C 3 152 GLN 152 131  131  GLN GLN R    . n 
C 3 153 ASP 153 132  132  ASP ASP R    . n 
C 3 154 LEU 154 133  133  LEU LEU R    . n 
C 3 155 ALA 155 134  134  ALA ALA R    . n 
C 3 156 ARG 156 135  135  ARG ARG R    . n 
C 3 157 SER 157 136  136  SER SER R    . n 
C 3 158 TYR 158 137  137  TYR TYR R    . n 
C 3 159 GLY 159 138  138  GLY GLY R    . n 
C 3 160 ILE 160 139  139  ILE ILE R    . n 
C 3 161 PRO 161 140  140  PRO PRO R    . n 
C 3 162 PHE 162 141  141  PHE PHE R    . n 
C 3 163 ILE 163 142  142  ILE ILE R    . n 
C 3 164 GLU 164 143  143  GLU GLU R    . n 
C 3 165 THR 165 144  144  THR THR R    . n 
C 3 166 SER 166 145  145  SER SER R    . n 
C 3 167 ALA 167 146  146  ALA ALA R    . n 
C 3 168 LYS 168 147  147  LYS LYS R    . n 
C 3 169 THR 169 148  148  THR THR R    . n 
C 3 170 ARG 170 149  149  ARG ARG R    . n 
C 3 171 GLN 171 150  150  GLN GLN R    . n 
C 3 172 GLY 172 151  151  GLY GLY R    . n 
C 3 173 VAL 173 152  152  VAL VAL R    . n 
C 3 174 ASP 174 153  153  ASP ASP R    . n 
C 3 175 ASP 175 154  154  ASP ASP R    . n 
C 3 176 ALA 176 155  155  ALA ALA R    . n 
C 3 177 PHE 177 156  156  PHE PHE R    . n 
C 3 178 TYR 178 157  157  TYR TYR R    . n 
C 3 179 THR 179 158  158  THR THR R    . n 
C 3 180 LEU 180 159  159  LEU LEU R    . n 
C 3 181 VAL 181 160  160  VAL VAL R    . n 
C 3 182 ARG 182 161  161  ARG ARG R    . n 
C 3 183 GLU 183 162  162  GLU GLU R    . n 
C 3 184 ILE 184 163  163  ILE ILE R    . n 
C 3 185 ARG 185 164  164  ARG ARG R    . n 
C 3 186 LYS 186 165  ?    ?   ?   R    . n 
C 3 187 HIS 187 166  ?    ?   ?   R    . n 
C 3 188 LYS 188 167  ?    ?   ?   R    . n 
C 3 189 GLU 189 168  ?    ?   ?   R    . n 
C 3 190 LYS 190 169  ?    ?   ?   R    . n 
D 4 1   GLN 1   1    ?    ?   ?   N    . n 
D 4 2   VAL 2   2    ?    ?   ?   N    . n 
D 4 3   GLN 3   3    3    GLN GLN N    . n 
D 4 4   LEU 4   4    4    LEU LEU N    . n 
D 4 5   VAL 5   5    5    VAL VAL N    . n 
D 4 6   GLU 6   6    6    GLU GLU N    . n 
D 4 7   SER 7   7    7    SER SER N    . n 
D 4 8   GLY 8   8    8    GLY GLY N    . n 
D 4 9   GLY 9   9    9    GLY GLY N    . n 
D 4 10  GLY 10  10   10   GLY GLY N    . n 
D 4 11  LEU 11  11   11   LEU LEU N    . n 
D 4 12  VAL 12  12   12   VAL VAL N    . n 
D 4 13  GLN 13  13   13   GLN GLN N    . n 
D 4 14  ALA 14  14   14   ALA ALA N    . n 
D 4 15  GLU 15  15   15   GLU GLU N    . n 
D 4 16  GLY 16  16   16   GLY GLY N    . n 
D 4 17  SER 17  17   17   SER SER N    . n 
D 4 18  LEU 18  18   18   LEU LEU N    . n 
D 4 19  ARG 19  19   19   ARG ARG N    . n 
D 4 20  LEU 20  20   20   LEU LEU N    . n 
D 4 21  SER 21  21   21   SER SER N    . n 
D 4 22  CYS 22  22   22   CYS CYS N    . n 
D 4 23  LEU 23  23   23   LEU LEU N    . n 
D 4 24  VAL 24  24   24   VAL VAL N    . n 
D 4 25  SER 25  25   25   SER SER N    . n 
D 4 26  GLY 26  26   ?    ?   ?   N    . n 
D 4 27  ASP 27  27   ?    ?   ?   N    . n 
D 4 28  ILE 28  28   ?    ?   ?   N    . n 
D 4 29  VAL 29  29   ?    ?   ?   N    . n 
D 4 30  ARG 30  30   30   ARG ARG N    . n 
D 4 31  SER 31  31   31   SER SER N    . n 
D 4 32  ASN 32  32   32   ASN ASN N    . n 
D 4 33  LEU 33  33   33   LEU LEU N    . n 
D 4 34  MET 34  34   34   MET MET N    . n 
D 4 35  GLY 35  35   35   GLY GLY N    . n 
D 4 36  TRP 36  36   36   TRP TRP N    . n 
D 4 37  TYR 37  37   37   TYR TYR N    . n 
D 4 38  ARG 38  38   38   ARG ARG N    . n 
D 4 39  GLN 39  39   39   GLN GLN N    . n 
D 4 40  ALA 40  40   40   ALA ALA N    . n 
D 4 41  PRO 41  41   41   PRO PRO N    . n 
D 4 42  GLY 42  42   42   GLY GLY N    . n 
D 4 43  LYS 43  43   43   LYS LYS N    . n 
D 4 44  GLN 44  44   44   GLN GLN N    . n 
D 4 45  ARG 45  45   45   ARG ARG N    . n 
D 4 46  GLU 46  46   46   GLU GLU N    . n 
D 4 47  PHE 47  47   47   PHE PHE N    . n 
D 4 48  VAL 48  48   48   VAL VAL N    . n 
D 4 49  ALA 49  49   49   ALA ALA N    . n 
D 4 50  ARG 50  50   50   ARG ARG N    . n 
D 4 51  ILE 51  51   51   ILE ILE N    . n 
D 4 52  ASN 52  52   52   ASN ASN N    . n 
D 4 53  PRO 53  53   53   PRO PRO N    . n 
D 4 54  THR 54  54   54   THR THR N    . n 
D 4 55  GLY 55  55   55   GLY GLY N    . n 
D 4 56  SER 56  56   56   SER SER N    . n 
D 4 57  ALA 57  57   57   ALA ALA N    . n 
D 4 58  ASN 58  58   58   ASN ASN N    . n 
D 4 59  TYR 59  59   59   TYR TYR N    . n 
D 4 60  ALA 60  60   60   ALA ALA N    . n 
D 4 61  ASP 61  61   61   ASP ASP N    . n 
D 4 62  SER 62  62   62   SER SER N    . n 
D 4 63  VAL 63  63   63   VAL VAL N    . n 
D 4 64  ARG 64  64   64   ARG ARG N    . n 
D 4 65  GLY 65  65   65   GLY GLY N    . n 
D 4 66  ARG 66  66   66   ARG ARG N    . n 
D 4 67  PHE 67  67   67   PHE PHE N    . n 
D 4 68  THR 68  68   68   THR THR N    . n 
D 4 69  ILE 69  69   69   ILE ILE N    . n 
D 4 70  SER 70  70   70   SER SER N    . n 
D 4 71  LYS 71  71   71   LYS LYS N    . n 
D 4 72  ASP 72  72   72   ASP ASP N    . n 
D 4 73  ASN 73  73   73   ASN ASN N    . n 
D 4 74  SER 74  74   74   SER SER N    . n 
D 4 75  LYS 75  75   75   LYS LYS N    . n 
D 4 76  LYS 76  76   76   LYS LYS N    . n 
D 4 77  THR 77  77   77   THR THR N    . n 
D 4 78  LEU 78  78   78   LEU LEU N    . n 
D 4 79  TYR 79  79   79   TYR TYR N    . n 
D 4 80  LEU 80  80   80   LEU LEU N    . n 
D 4 81  GLN 81  81   81   GLN GLN N    . n 
D 4 82  MET 82  82   82   MET MET N    . n 
D 4 83  GLY 83  83   83   GLY GLY N    . n 
D 4 84  SER 84  84   84   SER SER N    . n 
D 4 85  LEU 85  85   85   LEU LEU N    . n 
D 4 86  GLN 86  86   86   GLN GLN N    . n 
D 4 87  PRO 87  87   87   PRO PRO N    . n 
D 4 88  GLU 88  88   88   GLU GLU N    . n 
D 4 89  ASP 89  89   89   ASP ASP N    . n 
D 4 90  THR 90  90   90   THR THR N    . n 
D 4 91  ALA 91  91   91   ALA ALA N    . n 
D 4 92  VAL 92  92   92   VAL VAL N    . n 
D 4 93  TYR 93  93   93   TYR TYR N    . n 
D 4 94  TYR 94  94   94   TYR TYR N    . n 
D 4 95  CYS 95  95   95   CYS CYS N    . n 
D 4 96  ARG 96  96   96   ARG ARG N    . n 
D 4 97  LEU 97  97   97   LEU LEU N    . n 
D 4 98  ILE 98  98   98   ILE ILE N    . n 
D 4 99  GLN 99  99   99   GLN GLN N    . n 
D 4 100 ASN 100 100  100  ASN ASN N    . n 
D 4 101 ARG 101 101  101  ARG ARG N    . n 
D 4 102 ASP 102 102  102  ASP ASP N    . n 
D 4 103 TYR 103 103  103  TYR TYR N    . n 
D 4 104 TRP 104 104  104  TRP TRP N    . n 
D 4 105 GLY 105 105  105  GLY GLY N    . n 
D 4 106 GLN 106 106  106  GLN GLN N    . n 
D 4 107 GLY 107 107  107  GLY GLY N    . n 
D 4 108 THR 108 108  108  THR THR N    . n 
D 4 109 GLN 109 109  109  GLN GLN N    . n 
D 4 110 VAL 110 110  110  VAL VAL N    . n 
D 4 111 THR 111 111  111  THR THR N    . n 
D 4 112 VAL 112 112  112  VAL VAL N    . n 
D 4 113 SER 113 113  113  SER SER N    . n 
D 4 114 SER 114 114  114  SER SER N    . n 
D 4 115 HIS 115 115  115  HIS HIS N    . n 
D 4 116 HIS 116 116  ?    ?   ?   N    . n 
D 4 117 HIS 117 117  ?    ?   ?   N    . n 
D 4 118 HIS 118 118  ?    ?   ?   N    . n 
D 4 119 HIS 119 119  ?    ?   ?   N    . n 
D 4 120 HIS 120 120  ?    ?   ?   N    . n 
D 4 121 GLU 121 121  ?    ?   ?   N    . n 
D 4 122 PRO 122 122  ?    ?   ?   N    . n 
D 4 123 GLU 123 123  ?    ?   ?   N    . n 
D 4 124 ALA 124 124  ?    ?   ?   N    . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jan.steyaert@vub.be 
_pdbx_contact_author.name_first         Jan 
_pdbx_contact_author.name_last          Steyaert 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3825-874X 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 5 HOH 1  1101 4  HOH HOH AAZA . 
E 5 HOH 2  1102 8  HOH HOH AAZA . 
E 5 HOH 3  1103 5  HOH HOH AAZA . 
E 5 HOH 4  1104 2  HOH HOH AAZA . 
E 5 HOH 5  1105 7  HOH HOH AAZA . 
E 5 HOH 6  1106 6  HOH HOH AAZA . 
E 5 HOH 7  1107 11 HOH HOH AAZA . 
E 5 HOH 8  1108 1  HOH HOH AAZA . 
E 5 HOH 9  1109 10 HOH HOH AAZA . 
E 5 HOH 10 1110 3  HOH HOH AAZA . 
F 5 HOH 1  201  9  HOH HOH C    . 
F 5 HOH 2  202  13 HOH HOH C    . 
G 5 HOH 1  201  18 HOH HOH R    . 
G 5 HOH 2  202  19 HOH HOH R    . 
G 5 HOH 3  203  17 HOH HOH R    . 
G 5 HOH 4  204  15 HOH HOH R    . 
G 5 HOH 5  205  14 HOH HOH R    . 
G 5 HOH 6  206  16 HOH HOH R    . 
H 5 HOH 1  201  12 HOH HOH N    . 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6380  ? 
1 MORE         -16   ? 
1 'SSA (A^2)'  38230 ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2023-11-01 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1  x,y,z                
2  -y,x,z               
3  y,-x,z               
4  x,-y,-z              
5  -x,y,-z              
6  -x,-y,z              
7  y,x,-z               
8  -y,-x,-z             
9  x+1/2,y+1/2,z+1/2    
10 -y+1/2,x+1/2,z+1/2   
11 y+1/2,-x+1/2,z+1/2   
12 x+1/2,-y+1/2,-z+1/2  
13 -x+1/2,y+1/2,-z+1/2  
14 -x+1/2,-y+1/2,z+1/2  
15 y+1/2,x+1/2,-z+1/2   
16 -y+1/2,-x+1/2,-z+1/2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? .           4 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER AAZA 582  ? ? 179.68  166.55  
2  1 ILE AAZA 598  ? ? -170.15 120.07  
3  1 PHE AAZA 677  ? ? -63.56  33.77   
4  1 ARG AAZA 678  ? ? -153.41 -45.77  
5  1 TYR AAZA 681  ? ? -112.26 -88.34  
6  1 HIS AAZA 700  ? ? -140.55 39.16   
7  1 LYS AAZA 724  ? ? -64.31  1.39    
8  1 LYS AAZA 727  ? ? -62.84  11.15   
9  1 LYS AAZA 741  ? ? -96.12  39.40   
10 1 SER AAZA 756  ? ? -107.14 -167.14 
11 1 ILE AAZA 765  ? ? -109.31 -61.08  
12 1 HIS AAZA 770  ? ? -112.75 69.15   
13 1 SER AAZA 807  ? ? 47.98   24.98   
14 1 HIS AAZA 951  ? ? 69.39   -2.05   
15 1 GLU AAZA 1017 ? ? -157.77 86.64   
16 1 PRO AAZA 1021 ? ? -59.31  -71.92  
17 1 LEU AAZA 1035 ? ? -107.70 70.07   
18 1 PRO AAZA 1042 ? ? -79.67  -158.06 
19 1 SER C    7    ? ? -162.30 -164.23 
20 1 CYS C    22   ? ? -152.50 41.64   
21 1 ALA C    49   ? ? -172.38 138.91  
22 1 SER C    54   ? ? 60.80   101.44  
23 1 VAL C    65   ? ? -92.76  -62.01  
24 1 ASP C    66   ? ? -157.47 70.28   
25 1 LEU C    102  ? ? -163.16 109.52  
26 1 PRO C    108  ? ? -59.66  -7.78   
27 1 THR C    120  ? ? -147.00 56.58   
28 1 ASP R    38   ? ? -59.03  -8.60   
29 1 ASP R    92   ? ? -66.47  0.01    
30 1 ASP R    105  ? ? 76.56   65.94   
31 1 PRO R    121  ? ? -101.61 -169.17 
32 1 LYS R    147  ? ? -60.94  20.58   
33 1 THR R    148  ? ? -155.91 -1.31   
34 1 ARG R    149  ? ? 53.49   8.40    
35 1 SER N    17   ? ? -145.63 58.36   
36 1 PRO N    53   ? ? -49.93  -15.42  
37 1 SER N    56   ? ? -166.64 -164.03 
38 1 ASN N    73   ? ? -39.13  -36.63  
39 1 LYS N    76   ? ? -51.43  69.42   
40 1 GLN N    99   ? ? -108.17 -64.40  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 AAZA MET 543  ? A MET 1   
2   1 Y 1 AAZA GLY 544  ? A GLY 2   
3   1 Y 1 AAZA SER 545  ? A SER 3   
4   1 Y 1 AAZA SER 546  ? A SER 4   
5   1 Y 1 AAZA HIS 547  ? A HIS 5   
6   1 Y 1 AAZA HIS 548  ? A HIS 6   
7   1 Y 1 AAZA HIS 549  ? A HIS 7   
8   1 Y 1 AAZA HIS 550  ? A HIS 8   
9   1 Y 1 AAZA HIS 551  ? A HIS 9   
10  1 Y 1 AAZA HIS 552  ? A HIS 10  
11  1 Y 1 AAZA SER 553  ? A SER 11  
12  1 Y 1 AAZA SER 554  ? A SER 12  
13  1 Y 1 AAZA GLY 555  ? A GLY 13  
14  1 Y 1 AAZA LEU 556  ? A LEU 14  
15  1 Y 1 AAZA VAL 557  ? A VAL 15  
16  1 Y 1 AAZA PRO 558  ? A PRO 16  
17  1 Y 1 AAZA ARG 559  ? A ARG 17  
18  1 Y 1 AAZA GLY 560  ? A GLY 18  
19  1 Y 1 AAZA SER 561  ? A SER 19  
20  1 Y 1 AAZA HIS 562  ? A HIS 20  
21  1 Y 1 AAZA MET 563  ? A MET 21  
22  1 Y 1 AAZA GLU 564  ? A GLU 22  
23  1 Y 1 AAZA GLU 565  ? A GLU 23  
24  1 Y 1 AAZA GLN 566  ? A GLN 24  
25  1 Y 1 AAZA MET 567  ? A MET 25  
26  1 Y 1 AAZA ARG 568  ? A ARG 26  
27  1 Y 1 AAZA LEU 569  ? A LEU 27  
28  1 Y 1 AAZA MET 592  ? A MET 50  
29  1 Y 1 AAZA GLN 593  ? A GLN 51  
30  1 Y 1 AAZA PRO 594  ? A PRO 52  
31  1 Y 1 AAZA LYS 595  ? A LYS 53  
32  1 Y 1 AAZA GLU 654  ? A GLU 112 
33  1 Y 1 AAZA PRO 655  ? A PRO 113 
34  1 Y 1 AAZA THR 656  ? A THR 114 
35  1 Y 1 AAZA GLU 657  ? A GLU 115 
36  1 Y 1 AAZA ALA 658  ? A ALA 116 
37  1 Y 1 AAZA ASP 659  ? A ASP 117 
38  1 Y 1 AAZA ARG 660  ? A ARG 118 
39  1 Y 1 AAZA ILE 661  ? A ILE 119 
40  1 Y 1 AAZA ALA 662  ? A ALA 120 
41  1 Y 1 AAZA ILE 663  ? A ILE 121 
42  1 Y 1 AAZA GLU 664  ? A GLU 122 
43  1 Y 1 AAZA ASN 665  ? A ASN 123 
44  1 Y 1 AAZA GLY 666  ? A GLY 124 
45  1 Y 1 AAZA ASP 667  ? A ASP 125 
46  1 Y 1 AAZA GLN 668  ? A GLN 126 
47  1 Y 1 AAZA PRO 669  ? A PRO 127 
48  1 Y 1 AAZA LEU 670  ? A LEU 128 
49  1 Y 1 AAZA ARG 744  ? A ARG 202 
50  1 Y 1 AAZA ASP 745  ? A ASP 203 
51  1 Y 1 AAZA ASN 746  ? A ASN 204 
52  1 Y 1 AAZA GLY 747  ? A GLY 205 
53  1 Y 1 AAZA PRO 748  ? A PRO 206 
54  1 Y 1 AAZA GLY 749  ? A GLY 207 
55  1 Y 1 AAZA HIS 750  ? A HIS 208 
56  1 Y 1 AAZA ASN 751  ? A ASN 209 
57  1 Y 1 AAZA ASN 1044 ? A ASN 502 
58  1 Y 1 AAZA PRO 1045 ? A PRO 503 
59  1 Y 1 AAZA ARG 1046 ? A ARG 504 
60  1 Y 1 AAZA PRO 1047 ? A PRO 505 
61  1 Y 1 AAZA GLY 1048 ? A GLY 506 
62  1 Y 1 AAZA THR 1049 ? A THR 507 
63  1 Y 1 C    GLN 1    ? B GLN 1   
64  1 Y 1 C    LEU 11   ? B LEU 11  
65  1 Y 1 C    VAL 12   ? B VAL 12  
66  1 Y 1 C    GLN 13   ? B GLN 13  
67  1 Y 1 C    ALA 14   ? B ALA 14  
68  1 Y 1 C    GLY 15   ? B GLY 15  
69  1 Y 1 C    GLY 16   ? B GLY 16  
70  1 Y 1 C    SER 17   ? B SER 17  
71  1 Y 1 C    LEU 18   ? B LEU 18  
72  1 Y 1 C    ASN 27   ? B ASN 27  
73  1 Y 1 C    GLN 39   ? B GLN 39  
74  1 Y 1 C    THR 40   ? B THR 40  
75  1 Y 1 C    PRO 41   ? B PRO 41  
76  1 Y 1 C    GLY 42   ? B GLY 42  
77  1 Y 1 C    VAL 68   ? B VAL 68  
78  1 Y 1 C    LYS 69   ? B LYS 69  
79  1 Y 1 C    GLY 70   ? B GLY 70  
80  1 Y 1 C    ARG 71   ? B ARG 71  
81  1 Y 1 C    PHE 72   ? B PHE 72  
82  1 Y 1 C    THR 73   ? B THR 73  
83  1 Y 1 C    ILE 74   ? B ILE 74  
84  1 Y 1 C    SER 75   ? B SER 75  
85  1 Y 1 C    GLY 76   ? B GLY 76  
86  1 Y 1 C    ASP 77   ? B ASP 77  
87  1 Y 1 C    ASN 78   ? B ASN 78  
88  1 Y 1 C    ALA 79   ? B ALA 79  
89  1 Y 1 C    LYS 80   ? B LYS 80  
90  1 Y 1 C    ASN 81   ? B ASN 81  
91  1 Y 1 C    THR 82   ? B THR 82  
92  1 Y 1 C    VAL 83   ? B VAL 83  
93  1 Y 1 C    TYR 84   ? B TYR 84  
94  1 Y 1 C    LEU 85   ? B LEU 85  
95  1 Y 1 C    GLN 86   ? B GLN 86  
96  1 Y 1 C    MET 87   ? B MET 87  
97  1 Y 1 C    SER 88   ? B SER 88  
98  1 Y 1 C    SER 89   ? B SER 89  
99  1 Y 1 C    LEU 90   ? B LEU 90  
100 1 Y 1 C    LYS 91   ? B LYS 91  
101 1 Y 1 C    PRO 92   ? B PRO 92  
102 1 Y 1 C    GLU 93   ? B GLU 93  
103 1 Y 1 C    ASP 94   ? B ASP 94  
104 1 Y 1 C    THR 95   ? B THR 95  
105 1 Y 1 C    VAL 124  ? B VAL 124 
106 1 Y 1 C    SER 125  ? B SER 125 
107 1 Y 1 C    SER 126  ? B SER 126 
108 1 Y 1 C    HIS 127  ? B HIS 127 
109 1 Y 1 C    HIS 128  ? B HIS 128 
110 1 Y 1 C    HIS 129  ? B HIS 129 
111 1 Y 1 C    HIS 130  ? B HIS 130 
112 1 Y 1 C    HIS 131  ? B HIS 131 
113 1 Y 1 C    HIS 132  ? B HIS 132 
114 1 Y 1 C    GLU 133  ? B GLU 133 
115 1 Y 1 C    PRO 134  ? B PRO 134 
116 1 Y 1 C    GLU 135  ? B GLU 135 
117 1 Y 1 C    ALA 136  ? B ALA 136 
118 1 Y 1 R    MET -20  ? C MET 1   
119 1 Y 1 R    GLY -19  ? C GLY 2   
120 1 Y 1 R    SER -18  ? C SER 3   
121 1 Y 1 R    SER -17  ? C SER 4   
122 1 Y 1 R    HIS -16  ? C HIS 5   
123 1 Y 1 R    HIS -15  ? C HIS 6   
124 1 Y 1 R    HIS -14  ? C HIS 7   
125 1 Y 1 R    HIS -13  ? C HIS 8   
126 1 Y 1 R    HIS -12  ? C HIS 9   
127 1 Y 1 R    HIS -11  ? C HIS 10  
128 1 Y 1 R    SER -10  ? C SER 11  
129 1 Y 1 R    SER -9   ? C SER 12  
130 1 Y 1 R    GLY -8   ? C GLY 13  
131 1 Y 1 R    GLU -7   ? C GLU 14  
132 1 Y 1 R    ASN -6   ? C ASN 15  
133 1 Y 1 R    LEU -5   ? C LEU 16  
134 1 Y 1 R    TYR -4   ? C TYR 17  
135 1 Y 1 R    PHE -3   ? C PHE 18  
136 1 Y 1 R    GLN -2   ? C GLN 19  
137 1 Y 1 R    GLY -1   ? C GLY 20  
138 1 Y 1 R    SER 0    ? C SER 21  
139 1 Y 1 R    ASN 26   ? C ASN 47  
140 1 Y 1 R    HIS 27   ? C HIS 48  
141 1 Y 1 R    PHE 28   ? C PHE 49  
142 1 Y 1 R    VAL 29   ? C VAL 50  
143 1 Y 1 R    ASP 30   ? C ASP 51  
144 1 Y 1 R    LYS 165  ? C LYS 186 
145 1 Y 1 R    HIS 166  ? C HIS 187 
146 1 Y 1 R    LYS 167  ? C LYS 188 
147 1 Y 1 R    GLU 168  ? C GLU 189 
148 1 Y 1 R    LYS 169  ? C LYS 190 
149 1 Y 1 N    GLN 1    ? D GLN 1   
150 1 Y 1 N    VAL 2    ? D VAL 2   
151 1 Y 1 N    GLY 26   ? D GLY 26  
152 1 Y 1 N    ASP 27   ? D ASP 27  
153 1 Y 1 N    ILE 28   ? D ILE 28  
154 1 Y 1 N    VAL 29   ? D VAL 29  
155 1 Y 1 N    HIS 116  ? D HIS 116 
156 1 Y 1 N    HIS 117  ? D HIS 117 
157 1 Y 1 N    HIS 118  ? D HIS 118 
158 1 Y 1 N    HIS 119  ? D HIS 119 
159 1 Y 1 N    HIS 120  ? D HIS 120 
160 1 Y 1 N    GLU 121  ? D GLU 121 
161 1 Y 1 N    PRO 122  ? D PRO 122 
162 1 Y 1 N    GLU 123  ? D GLU 123 
163 1 Y 1 N    ALA 124  ? D ALA 124 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'Research Foundation - Flanders (FWO)' 
_pdbx_audit_support.country                Belgium 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_space_group.name_H-M_alt     'I 4 2 2' 
_space_group.name_Hall        'I 4 2' 
_space_group.IT_number        97 
_space_group.crystal_system   tetragonal 
_space_group.id               1 
# 
