data_8FWH
# 
_entry.id   8FWH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.379 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8FWH         pdb_00008fwh 10.2210/pdb8fwh/pdb 
WWPDB D_1000271429 ?            ?                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8FWH 
_pdbx_database_status.recvd_initial_deposition_date   2023-01-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mishra, A.K.'   1 ? 
'Agnihotri, P.'  2 ? 
'Mariuzza, R.A.' 3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Structure 
_citation.journal_id_ASTM           STRUE6 
_citation.journal_id_CSD            2005 
_citation.journal_id_ISSN           0969-2126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.' 
_citation.year                      2023 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.str.2023.07.013 
_citation.pdbx_database_id_PubMed   37619561 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mishra, A.K.'   1 ? 
primary 'Shahid, S.'     2 ? 
primary 'Karade, S.S.'   3 ? 
primary 'Agnihotri, P.'  4 ? 
primary 'Kolesnikov, A.' 5 ? 
primary 'Hasan, S.S.'    6 ? 
primary 'Mariuzza, R.A.' 7 ? 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   106.136 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8FWH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     159.287 
_cell.length_a_esd                 ? 
_cell.length_b                     44.390 
_cell.length_b_esd                 ? 
_cell.length_c                     89.084 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8FWH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Anti-human LAG3 (22D2) heavy chain' 23959.947 1  ? ? Fab ? 
2 polymer     man 'Anti-human LAG3 (22D2) light chain' 23688.984 1  ? ? Fab ? 
3 non-polymer syn 1,2-ETHANEDIOL                       62.068    1  ? ? ?   ? 
4 water       nat water                                18.015    27 ? ? ?   ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVLLLQSGPELVKPGTSVKIPCKASGYTFTDYNVDWVKQRHGKGLEWIGDINPNNGGTIYSQKFKGKATLTVDKSSSTAF
MELRSLTSEDTAVYFCARNYRWFGAMDHWGQGTSVTVSSTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKT
;
;EVLLLQSGPELVKPGTSVKIPCKASGYTFTDYNVDWVKQRHGKGLEWIGDINPNNGGTIYSQKFKGKATLTVDKSSSTAF
MELRSLTSEDTAVYFCARNYRWFGAMDHWGQGTSVTVSSTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKT
;
HHH ? 
2 'polypeptide(L)' no no 
;DIVLTQSPASLAVSPGQRATISCKASQSLDYEGDSDMNWYQQKPGQPPRLLISGASNLESGIPARFSGSGSGTDFTVNIH
PVEEEDAATYYCQQSTEDPRTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKYQWKVDNALQS
GNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DIVLTQSPASLAVSPGQRATISCKASQSLDYEGDSDMNWYQQKPGQPPRLLISGASNLESGIPARFSGSGSGTDFTVNIH
PVEEEDAATYYCQQSTEDPRTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKYQWKVDNALQS
GNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
LLL ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   LEU n 
1 4   LEU n 
1 5   LEU n 
1 6   GLN n 
1 7   SER n 
1 8   GLY n 
1 9   PRO n 
1 10  GLU n 
1 11  LEU n 
1 12  VAL n 
1 13  LYS n 
1 14  PRO n 
1 15  GLY n 
1 16  THR n 
1 17  SER n 
1 18  VAL n 
1 19  LYS n 
1 20  ILE n 
1 21  PRO n 
1 22  CYS n 
1 23  LYS n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  TYR n 
1 28  THR n 
1 29  PHE n 
1 30  THR n 
1 31  ASP n 
1 32  TYR n 
1 33  ASN n 
1 34  VAL n 
1 35  ASP n 
1 36  TRP n 
1 37  VAL n 
1 38  LYS n 
1 39  GLN n 
1 40  ARG n 
1 41  HIS n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  ILE n 
1 49  GLY n 
1 50  ASP n 
1 51  ILE n 
1 52  ASN n 
1 53  PRO n 
1 54  ASN n 
1 55  ASN n 
1 56  GLY n 
1 57  GLY n 
1 58  THR n 
1 59  ILE n 
1 60  TYR n 
1 61  SER n 
1 62  GLN n 
1 63  LYS n 
1 64  PHE n 
1 65  LYS n 
1 66  GLY n 
1 67  LYS n 
1 68  ALA n 
1 69  THR n 
1 70  LEU n 
1 71  THR n 
1 72  VAL n 
1 73  ASP n 
1 74  LYS n 
1 75  SER n 
1 76  SER n 
1 77  SER n 
1 78  THR n 
1 79  ALA n 
1 80  PHE n 
1 81  MET n 
1 82  GLU n 
1 83  LEU n 
1 84  ARG n 
1 85  SER n 
1 86  LEU n 
1 87  THR n 
1 88  SER n 
1 89  GLU n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  VAL n 
1 94  TYR n 
1 95  PHE n 
1 96  CYS n 
1 97  ALA n 
1 98  ARG n 
1 99  ASN n 
1 100 TYR n 
1 101 ARG n 
1 102 TRP n 
1 103 PHE n 
1 104 GLY n 
1 105 ALA n 
1 106 MET n 
1 107 ASP n 
1 108 HIS n 
1 109 TRP n 
1 110 GLY n 
1 111 GLN n 
1 112 GLY n 
1 113 THR n 
1 114 SER n 
1 115 VAL n 
1 116 THR n 
1 117 VAL n 
1 118 SER n 
1 119 SER n 
1 120 THR n 
1 121 LYS n 
1 122 GLY n 
1 123 PRO n 
1 124 SER n 
1 125 VAL n 
1 126 PHE n 
1 127 PRO n 
1 128 LEU n 
1 129 ALA n 
1 130 PRO n 
1 131 SER n 
1 132 SER n 
1 133 LYS n 
1 134 SER n 
1 135 THR n 
1 136 SER n 
1 137 GLY n 
1 138 GLY n 
1 139 THR n 
1 140 ALA n 
1 141 ALA n 
1 142 LEU n 
1 143 GLY n 
1 144 CYS n 
1 145 LEU n 
1 146 VAL n 
1 147 LYS n 
1 148 ASP n 
1 149 TYR n 
1 150 PHE n 
1 151 PRO n 
1 152 GLU n 
1 153 PRO n 
1 154 VAL n 
1 155 THR n 
1 156 VAL n 
1 157 SER n 
1 158 TRP n 
1 159 ASN n 
1 160 SER n 
1 161 GLY n 
1 162 ALA n 
1 163 LEU n 
1 164 THR n 
1 165 SER n 
1 166 GLY n 
1 167 VAL n 
1 168 HIS n 
1 169 THR n 
1 170 PHE n 
1 171 PRO n 
1 172 ALA n 
1 173 VAL n 
1 174 LEU n 
1 175 GLN n 
1 176 SER n 
1 177 SER n 
1 178 GLY n 
1 179 LEU n 
1 180 TYR n 
1 181 SER n 
1 182 LEU n 
1 183 SER n 
1 184 SER n 
1 185 VAL n 
1 186 VAL n 
1 187 THR n 
1 188 VAL n 
1 189 PRO n 
1 190 SER n 
1 191 SER n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 THR n 
1 196 GLN n 
1 197 THR n 
1 198 TYR n 
1 199 ILE n 
1 200 CYS n 
1 201 ASN n 
1 202 VAL n 
1 203 ASN n 
1 204 HIS n 
1 205 LYS n 
1 206 PRO n 
1 207 SER n 
1 208 ASN n 
1 209 THR n 
1 210 LYS n 
1 211 VAL n 
1 212 ASP n 
1 213 LYS n 
1 214 ARG n 
1 215 VAL n 
1 216 GLU n 
1 217 PRO n 
1 218 LYS n 
1 219 SER n 
1 220 CYS n 
1 221 ASP n 
1 222 LYS n 
1 223 THR n 
2 1   ASP n 
2 2   ILE n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   ALA n 
2 10  SER n 
2 11  LEU n 
2 12  ALA n 
2 13  VAL n 
2 14  SER n 
2 15  PRO n 
2 16  GLY n 
2 17  GLN n 
2 18  ARG n 
2 19  ALA n 
2 20  THR n 
2 21  ILE n 
2 22  SER n 
2 23  CYS n 
2 24  LYS n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  SER n 
2 29  LEU n 
2 30  ASP n 
2 31  TYR n 
2 32  GLU n 
2 33  GLY n 
2 34  ASP n 
2 35  SER n 
2 36  ASP n 
2 37  MET n 
2 38  ASN n 
2 39  TRP n 
2 40  TYR n 
2 41  GLN n 
2 42  GLN n 
2 43  LYS n 
2 44  PRO n 
2 45  GLY n 
2 46  GLN n 
2 47  PRO n 
2 48  PRO n 
2 49  ARG n 
2 50  LEU n 
2 51  LEU n 
2 52  ILE n 
2 53  SER n 
2 54  GLY n 
2 55  ALA n 
2 56  SER n 
2 57  ASN n 
2 58  LEU n 
2 59  GLU n 
2 60  SER n 
2 61  GLY n 
2 62  ILE n 
2 63  PRO n 
2 64  ALA n 
2 65  ARG n 
2 66  PHE n 
2 67  SER n 
2 68  GLY n 
2 69  SER n 
2 70  GLY n 
2 71  SER n 
2 72  GLY n 
2 73  THR n 
2 74  ASP n 
2 75  PHE n 
2 76  THR n 
2 77  VAL n 
2 78  ASN n 
2 79  ILE n 
2 80  HIS n 
2 81  PRO n 
2 82  VAL n 
2 83  GLU n 
2 84  GLU n 
2 85  GLU n 
2 86  ASP n 
2 87  ALA n 
2 88  ALA n 
2 89  THR n 
2 90  TYR n 
2 91  TYR n 
2 92  CYS n 
2 93  GLN n 
2 94  GLN n 
2 95  SER n 
2 96  THR n 
2 97  GLU n 
2 98  ASP n 
2 99  PRO n 
2 100 ARG n 
2 101 THR n 
2 102 PHE n 
2 103 GLY n 
2 104 GLY n 
2 105 GLY n 
2 106 THR n 
2 107 LYS n 
2 108 LEU n 
2 109 GLU n 
2 110 ILE n 
2 111 LYS n 
2 112 ARG n 
2 113 THR n 
2 114 VAL n 
2 115 ALA n 
2 116 ALA n 
2 117 PRO n 
2 118 SER n 
2 119 VAL n 
2 120 PHE n 
2 121 ILE n 
2 122 PHE n 
2 123 PRO n 
2 124 PRO n 
2 125 SER n 
2 126 ASP n 
2 127 GLU n 
2 128 GLN n 
2 129 LEU n 
2 130 LYS n 
2 131 SER n 
2 132 GLY n 
2 133 THR n 
2 134 ALA n 
2 135 SER n 
2 136 VAL n 
2 137 VAL n 
2 138 CYS n 
2 139 LEU n 
2 140 LEU n 
2 141 ASN n 
2 142 ASN n 
2 143 PHE n 
2 144 TYR n 
2 145 PRO n 
2 146 ARG n 
2 147 GLU n 
2 148 ALA n 
2 149 LYS n 
2 150 TYR n 
2 151 GLN n 
2 152 TRP n 
2 153 LYS n 
2 154 VAL n 
2 155 ASP n 
2 156 ASN n 
2 157 ALA n 
2 158 LEU n 
2 159 GLN n 
2 160 SER n 
2 161 GLY n 
2 162 ASN n 
2 163 SER n 
2 164 GLN n 
2 165 GLU n 
2 166 SER n 
2 167 VAL n 
2 168 THR n 
2 169 GLU n 
2 170 GLN n 
2 171 ASP n 
2 172 SER n 
2 173 LYS n 
2 174 ASP n 
2 175 SER n 
2 176 THR n 
2 177 TYR n 
2 178 SER n 
2 179 LEU n 
2 180 SER n 
2 181 SER n 
2 182 THR n 
2 183 LEU n 
2 184 THR n 
2 185 LEU n 
2 186 SER n 
2 187 LYS n 
2 188 ALA n 
2 189 ASP n 
2 190 TYR n 
2 191 GLU n 
2 192 LYS n 
2 193 HIS n 
2 194 LYS n 
2 195 VAL n 
2 196 TYR n 
2 197 ALA n 
2 198 CYS n 
2 199 GLU n 
2 200 VAL n 
2 201 THR n 
2 202 HIS n 
2 203 GLN n 
2 204 GLY n 
2 205 LEU n 
2 206 SER n 
2 207 SER n 
2 208 PRO n 
2 209 VAL n 
2 210 THR n 
2 211 LYS n 
2 212 SER n 
2 213 PHE n 
2 214 ASN n 
2 215 ARG n 
2 216 GLY n 
2 217 GLU n 
2 218 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 223 mouse ? ? ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? 'HEK 293 expi' ? ? ? ? ? 'pCDNA 3.4 topo' plasmid ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 218 mouse ? ? ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? 'HEK 293 expi' ? ? ? ? ? 'pCDNA 3.4 topo' plasmid ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8FWH 8FWH ? 1 ? 1 
2 PDB 8FWH 8FWH ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8FWH HHH 1 ? 223 ? 8FWH 1 ? 223 ? 1 223 
2 2 8FWH LLL 1 ? 218 ? 8FWH 1 ? 218 ? 1 218 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL  'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE       ?                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ?                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ?                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                 'C5 H11 N O2'    117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8FWH 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.17 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          61.26 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Tris-HCl, pH 7.5, 0.2 M sodium chloride, 10% w/v PEG8000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            295 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-03-14 
_diffrn_detector.pdbx_frequency               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.03 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 23-ID-D' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.03 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   23-ID-D 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8FWH 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.83 
_reflns.d_resolution_low                               85.57 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     13587 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           92.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          13.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.98 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.83 
_reflns_shell.d_res_low                                     2.90 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             13515 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.68 
_reflns_shell.pdbx_CC_star                                  0.90 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -3.808 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            -1.694 
_refine.aniso_B[2][2]                            10.894 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -5.230 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               77.32 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.940 
_refine.correlation_coeff_Fo_to_Fc_free          0.915 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8FWH 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.833 
_refine.ls_d_res_low                             42.75 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     13587 
_refine.ls_number_reflns_R_free                  706 
_refine.ls_number_reflns_R_work                  12881 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    92.903 
_refine.ls_percent_reflns_R_free                 5.196 
_refine.ls_R_factor_all                          0.219 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2767 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2164 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      'PDB entry 6WKM' 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       2.956 
_refine.pdbx_overall_ESU_R_Free                  0.407 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             20.341 
_refine.overall_SU_ML                            0.365 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        3145 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         4 
_refine_hist.number_atoms_solvent             27 
_refine_hist.number_atoms_total               3176 
_refine_hist.d_res_high                       2.833 
_refine_hist.d_res_low                        42.75 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.013   3237  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.017   2846  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.397  1.643   4434  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 1.279  1.569   6561  ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 7.019  5.000   428   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 38.039 23.459  133   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 17.024 15.000  447   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 18.474 15.000  10    ? r_dihedral_angle_4_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.052  0.200   445   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.005  0.020   3754  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.020   722   ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.236  0.200   503   ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.204  0.200   2698  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.163  0.200   1535  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.075  0.200   1666  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.146  0.200   66    ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.152  0.200   14    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.191  0.200   83    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.275  0.200   4     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 0.270  0.200   1     ? r_xyhbond_nbd_other            ? ? 
'X-RAY DIFFRACTION' ? 6.035  8.417   1714  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.034  8.413   1712  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 9.182  12.619  2137  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.180  12.619  2137  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 6.332  8.706   1523  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.330  8.705   1524  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 9.767  12.911  2296  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.765  12.910  2297  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 15.314 160.144 12936 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 15.303 160.147 12934 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.833  2.907  . . 47 754 73.2176 . . . . 0.341 . . . . . . . . . . . 0.467 
'X-RAY DIFFRACTION' 2.907  2.986  . . 41 841 86.3859 . . . . 0.316 . . . . . . . . . . . 0.342 
'X-RAY DIFFRACTION' 2.986  3.073  . . 60 875 91.4873 . . . . 0.302 . . . . . . . . . . . 0.363 
'X-RAY DIFFRACTION' 3.073  3.167  . . 56 871 93.8259 . . . . 0.303 . . . . . . . . . . . 0.370 
'X-RAY DIFFRACTION' 3.167  3.271  . . 54 853 96.0805 . . . . 0.281 . . . . . . . . . . . 0.376 
'X-RAY DIFFRACTION' 3.271  3.385  . . 43 840 96.1874 . . . . 0.250 . . . . . . . . . . . 0.276 
'X-RAY DIFFRACTION' 3.385  3.513  . . 39 805 95.2596 . . . . 0.240 . . . . . . . . . . . 0.311 
'X-RAY DIFFRACTION' 3.513  3.656  . . 32 785 95.1106 . . . . 0.236 . . . . . . . . . . . 0.284 
'X-RAY DIFFRACTION' 3.656  3.818  . . 44 749 96.0048 . . . . 0.219 . . . . . . . . . . . 0.291 
'X-RAY DIFFRACTION' 3.818  4.004  . . 44 726 96.0100 . . . . 0.202 . . . . . . . . . . . 0.241 
'X-RAY DIFFRACTION' 4.004  4.220  . . 33 677 96.2060 . . . . 0.159 . . . . . . . . . . . 0.196 
'X-RAY DIFFRACTION' 4.220  4.476  . . 39 667 96.4481 . . . . 0.162 . . . . . . . . . . . 0.212 
'X-RAY DIFFRACTION' 4.476  4.784  . . 40 582 96.1360 . . . . 0.169 . . . . . . . . . . . 0.237 
'X-RAY DIFFRACTION' 4.784  5.166  . . 29 591 95.6790 . . . . 0.172 . . . . . . . . . . . 0.262 
'X-RAY DIFFRACTION' 5.166  5.657  . . 28 528 96.5278 . . . . 0.171 . . . . . . . . . . . 0.249 
'X-RAY DIFFRACTION' 5.657  6.321  . . 21 490 94.6296 . . . . 0.208 . . . . . . . . . . . 0.233 
'X-RAY DIFFRACTION' 6.321  7.292  . . 24 423 94.5032 . . . . 0.234 . . . . . . . . . . . 0.387 
'X-RAY DIFFRACTION' 7.292  8.915  . . 12 368 94.7631 . . . . 0.185 . . . . . . . . . . . 0.178 
'X-RAY DIFFRACTION' 8.915  12.540 . . 13 282 94.2492 . . . . 0.201 . . . . . . . . . . . 0.222 
'X-RAY DIFFRACTION' 12.540 42.75  . . 7  174 91.8782 . . . . 0.319 . . . . . . . . . . . 0.329 
# 
_struct.entry_id                     8FWH 
_struct.title                        'Crystal structure of bivalent antibody Fab fragment of Anti-human LAG3 (22D2)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8FWH 
_struct_keywords.text            'Fab, inhibitory receptors, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 GLN A 62  ? LYS A 65  ? GLN HHH 62  LYS HHH 65  5 ? 4 
HELX_P HELX_P2 AA2 THR A 87  ? THR A 91  ? THR HHH 87  THR HHH 91  5 ? 5 
HELX_P HELX_P3 AA3 SER A 160 ? ALA A 162 ? SER HHH 160 ALA HHH 162 5 ? 3 
HELX_P HELX_P4 AA4 SER A 191 ? THR A 195 ? SER HHH 191 THR HHH 195 5 ? 5 
HELX_P HELX_P5 AA5 LYS A 205 ? ASN A 208 ? LYS HHH 205 ASN HHH 208 5 ? 4 
HELX_P HELX_P6 AA6 GLU B 83  ? ALA B 87  ? GLU LLL 83  ALA LLL 87  5 ? 5 
HELX_P HELX_P7 AA7 SER B 125 ? LYS B 130 ? SER LLL 125 LYS LLL 130 1 ? 6 
HELX_P HELX_P8 AA8 LYS B 187 ? LYS B 192 ? LYS LLL 187 LYS LLL 192 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22  SG ? ? ? 1_555 A CYS 96  SG ? ? HHH CYS 22  HHH CYS 96  1_555 ? ? ? ? ? ? ? 2.021 ? ? 
disulf2 disulf ? ? A CYS 144 SG ? ? ? 1_555 A CYS 200 SG ? ? HHH CYS 144 HHH CYS 200 1_555 ? ? ? ? ? ? ? 2.050 ? ? 
disulf3 disulf ? ? B CYS 23  SG ? ? ? 1_555 B CYS 92  SG ? ? LLL CYS 23  LLL CYS 92  1_555 ? ? ? ? ? ? ? 2.119 ? ? 
disulf4 disulf ? ? B CYS 138 SG ? ? ? 1_555 B CYS 198 SG ? ? LLL CYS 138 LLL CYS 198 1_555 ? ? ? ? ? ? ? 2.053 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 150 A . ? PHE 150 HHH PRO 151 A ? PRO 151 HHH 1 -13.85 
2 GLU 152 A . ? GLU 152 HHH PRO 153 A ? PRO 153 HHH 1 -7.06  
3 SER 7   B . ? SER 7   LLL PRO 8   B ? PRO 8   LLL 1 6.19   
4 HIS 80  B . ? HIS 80  LLL PRO 81  B ? PRO 81  LLL 1 -2.72  
5 ASP 98  B . ? ASP 98  LLL PRO 99  B ? PRO 99  LLL 1 12.28  
6 TYR 144 B . ? TYR 144 LLL PRO 145 B ? PRO 145 LLL 1 9.37   
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
AA7 ? 3 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 3 ? 
AB2 ? 2 ? 
AB3 ? 4 ? 
AB4 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 3   ? LEU A 5   ? LEU HHH 3   LEU HHH 5   
AA1 2 VAL A 18  ? SER A 25  ? VAL HHH 18  SER HHH 25  
AA1 3 THR A 78  ? LEU A 83  ? THR HHH 78  LEU HHH 83  
AA1 4 ALA A 68  ? ASP A 73  ? ALA HHH 68  ASP HHH 73  
AA2 1 GLU A 10  ? VAL A 12  ? GLU HHH 10  VAL HHH 12  
AA2 2 THR A 113 ? VAL A 117 ? THR HHH 113 VAL HHH 117 
AA2 3 ALA A 92  ? ASN A 99  ? ALA HHH 92  ASN HHH 99  
AA2 4 VAL A 34  ? GLN A 39  ? VAL HHH 34  GLN HHH 39  
AA2 5 LEU A 45  ? ILE A 51  ? LEU HHH 45  ILE HHH 51  
AA2 6 THR A 58  ? TYR A 60  ? THR HHH 58  TYR HHH 60  
AA3 1 GLU A 10  ? VAL A 12  ? GLU HHH 10  VAL HHH 12  
AA3 2 THR A 113 ? VAL A 117 ? THR HHH 113 VAL HHH 117 
AA3 3 ALA A 92  ? ASN A 99  ? ALA HHH 92  ASN HHH 99  
AA3 4 MET A 106 ? TRP A 109 ? MET HHH 106 TRP HHH 109 
AA4 1 SER A 124 ? LEU A 128 ? SER HHH 124 LEU HHH 128 
AA4 2 ALA A 140 ? LYS A 147 ? ALA HHH 140 LYS HHH 147 
AA4 3 SER A 183 ? VAL A 188 ? SER HHH 183 VAL HHH 188 
AA4 4 VAL A 167 ? THR A 169 ? VAL HHH 167 THR HHH 169 
AA5 1 THR A 155 ? TRP A 158 ? THR HHH 155 TRP HHH 158 
AA5 2 TYR A 198 ? HIS A 204 ? TYR HHH 198 HIS HHH 204 
AA5 3 THR A 209 ? VAL A 215 ? THR HHH 209 VAL HHH 215 
AA6 1 VAL A 173 ? LEU A 174 ? VAL HHH 173 LEU HHH 174 
AA6 2 TYR A 180 ? SER A 181 ? TYR HHH 180 SER HHH 181 
AA7 1 LEU B 4   ? SER B 7   ? LEU LLL 4   SER LLL 7   
AA7 2 SER B 22  ? ALA B 25  ? SER LLL 22  ALA LLL 25  
AA7 3 ASP B 74  ? PHE B 75  ? ASP LLL 74  PHE LLL 75  
AA8 1 SER B 10  ? VAL B 13  ? SER LLL 10  VAL LLL 13  
AA8 2 THR B 106 ? ILE B 110 ? THR LLL 106 ILE LLL 110 
AA8 3 ALA B 88  ? GLN B 94  ? ALA LLL 88  GLN LLL 94  
AA8 4 MET B 37  ? GLN B 42  ? MET LLL 37  GLN LLL 42  
AA8 5 ARG B 49  ? SER B 53  ? ARG LLL 49  SER LLL 53  
AA8 6 ASN B 57  ? LEU B 58  ? ASN LLL 57  LEU LLL 58  
AA9 1 SER B 10  ? VAL B 13  ? SER LLL 10  VAL LLL 13  
AA9 2 THR B 106 ? ILE B 110 ? THR LLL 106 ILE LLL 110 
AA9 3 ALA B 88  ? GLN B 94  ? ALA LLL 88  GLN LLL 94  
AA9 4 THR B 101 ? PHE B 102 ? THR LLL 101 PHE LLL 102 
AB1 1 ALA B 19  ? THR B 20  ? ALA LLL 19  THR LLL 20  
AB1 2 ASN B 78  ? ILE B 79  ? ASN LLL 78  ILE LLL 79  
AB1 3 PHE B 66  ? SER B 67  ? PHE LLL 66  SER LLL 67  
AB2 1 ASP B 30  ? TYR B 31  ? ASP LLL 30  TYR LLL 31  
AB2 2 ASP B 34  ? SER B 35  ? ASP LLL 34  SER LLL 35  
AB3 1 SER B 118 ? PHE B 122 ? SER LLL 118 PHE LLL 122 
AB3 2 THR B 133 ? PHE B 143 ? THR LLL 133 PHE LLL 143 
AB3 3 TYR B 177 ? SER B 186 ? TYR LLL 177 SER LLL 186 
AB3 4 SER B 163 ? VAL B 167 ? SER LLL 163 VAL LLL 167 
AB4 1 TYR B 150 ? VAL B 154 ? TYR LLL 150 VAL LLL 154 
AB4 2 TYR B 196 ? VAL B 200 ? TYR LLL 196 VAL LLL 200 
AB4 3 VAL B 209 ? PHE B 213 ? VAL LLL 209 PHE LLL 213 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 5   ? N LEU HHH 5   O LYS A 23  ? O LYS HHH 23  
AA1 2 3 N ILE A 20  ? N ILE HHH 20  O MET A 81  ? O MET HHH 81  
AA1 3 4 O PHE A 80  ? O PHE HHH 80  N THR A 71  ? N THR HHH 71  
AA2 1 2 N GLU A 10  ? N GLU HHH 10  O THR A 116 ? O THR HHH 116 
AA2 2 3 O VAL A 115 ? O VAL HHH 115 N ALA A 92  ? N ALA HHH 92  
AA2 3 4 O PHE A 95  ? O PHE HHH 95  N VAL A 37  ? N VAL HHH 37  
AA2 4 5 N TRP A 36  ? N TRP HHH 36  O ILE A 48  ? O ILE HHH 48  
AA2 5 6 N ASP A 50  ? N ASP HHH 50  O ILE A 59  ? O ILE HHH 59  
AA3 1 2 N GLU A 10  ? N GLU HHH 10  O THR A 116 ? O THR HHH 116 
AA3 2 3 O VAL A 115 ? O VAL HHH 115 N ALA A 92  ? N ALA HHH 92  
AA3 3 4 N ARG A 98  ? N ARG HHH 98  O ASP A 107 ? O ASP HHH 107 
AA4 1 2 N LEU A 128 ? N LEU HHH 128 O GLY A 143 ? O GLY HHH 143 
AA4 2 3 N LEU A 142 ? N LEU HHH 142 O VAL A 186 ? O VAL HHH 186 
AA4 3 4 O VAL A 185 ? O VAL HHH 185 N HIS A 168 ? N HIS HHH 168 
AA5 1 2 N THR A 155 ? N THR HHH 155 O ASN A 203 ? O ASN HHH 203 
AA5 2 3 N TYR A 198 ? N TYR HHH 198 O VAL A 215 ? O VAL HHH 215 
AA6 1 2 N VAL A 173 ? N VAL HHH 173 O SER A 181 ? O SER HHH 181 
AA7 1 2 N THR B 5   ? N THR LLL 5   O LYS B 24  ? O LYS LLL 24  
AA7 2 3 N CYS B 23  ? N CYS LLL 23  O PHE B 75  ? O PHE LLL 75  
AA8 1 2 N LEU B 11  ? N LEU LLL 11  O GLU B 109 ? O GLU LLL 109 
AA8 2 3 O THR B 106 ? O THR LLL 106 N TYR B 90  ? N TYR LLL 90  
AA8 3 4 O GLN B 93  ? O GLN LLL 93  N ASN B 38  ? N ASN LLL 38  
AA8 4 5 N GLN B 41  ? N GLN LLL 41  O ARG B 49  ? O ARG LLL 49  
AA8 5 6 N SER B 53  ? N SER LLL 53  O ASN B 57  ? O ASN LLL 57  
AA9 1 2 N LEU B 11  ? N LEU LLL 11  O GLU B 109 ? O GLU LLL 109 
AA9 2 3 O THR B 106 ? O THR LLL 106 N TYR B 90  ? N TYR LLL 90  
AA9 3 4 N GLN B 94  ? N GLN LLL 94  O THR B 101 ? O THR LLL 101 
AB1 1 2 N ALA B 19  ? N ALA LLL 19  O ILE B 79  ? O ILE LLL 79  
AB1 2 3 O ASN B 78  ? O ASN LLL 78  N SER B 67  ? N SER LLL 67  
AB2 1 2 N TYR B 31  ? N TYR LLL 31  O ASP B 34  ? O ASP LLL 34  
AB3 1 2 N PHE B 120 ? N PHE LLL 120 O LEU B 139 ? O LEU LLL 139 
AB3 2 3 N LEU B 140 ? N LEU LLL 140 O LEU B 179 ? O LEU LLL 179 
AB3 3 4 O THR B 182 ? O THR LLL 182 N GLN B 164 ? N GLN LLL 164 
AB4 1 2 N GLN B 151 ? N GLN LLL 151 O GLU B 199 ? O GLU LLL 199 
AB4 2 3 N VAL B 200 ? N VAL LLL 200 O VAL B 209 ? O VAL LLL 209 
# 
_atom_sites.entry_id                    8FWH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   0.006278 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.001816 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.022528 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011686 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.310  20.844 1.020 10.208 1.589 0.569  0.865 51.651 0.216   
H 1  1  0.493  10.511 0.323 26.126 0.140 3.142  0.041 57.800 0.003   
N 7  7  12.222 0.006  3.135 9.893  2.014 28.997 1.167 0.583  -11.538 
O 8  8  3.049  13.277 2.287 5.701  1.546 0.324  0.867 32.909 0.251   
S 16 16 6.905  1.468  5.203 22.215 1.438 0.254  1.586 56.172 0.867   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . GLU A 1 1   ? -27.915 3.548   8.652   1.000 117.859 0 1   GLU HHH N   1 ? 
ATOM   2    C CA  . GLU A 1 1   ? -29.053 4.226   9.356   1.000 120.572 0 1   GLU HHH CA  1 ? 
ATOM   3    C C   . GLU A 1 1   ? -29.364 3.455   10.642  1.000 108.827 0 1   GLU HHH C   1 ? 
ATOM   4    O O   . GLU A 1 1   ? -28.683 3.707   11.653  1.000 110.278 0 1   GLU HHH O   1 ? 
ATOM   5    C CB  . GLU A 1 1   ? -30.293 4.324   8.457   1.000 122.598 0 1   GLU HHH CB  1 ? 
ATOM   6    N N   . VAL A 1 2   ? -30.349 2.555   10.598  1.000 105.879 0 2   VAL HHH N   1 ? 
ATOM   7    C CA  . VAL A 1 2   ? -30.833 1.808   11.793  1.000 105.668 0 2   VAL HHH CA  1 ? 
ATOM   8    C C   . VAL A 1 2   ? -29.687 0.927   12.293  1.000 100.743 0 2   VAL HHH C   1 ? 
ATOM   9    O O   . VAL A 1 2   ? -29.291 0.006   11.548  1.000 85.956  0 2   VAL HHH O   1 ? 
ATOM   10   C CB  . VAL A 1 2   ? -32.085 0.966   11.494  1.000 112.671 0 2   VAL HHH CB  1 ? 
ATOM   11   C CG1 . VAL A 1 2   ? -32.543 0.240   12.754  1.000 122.320 0 2   VAL HHH CG1 1 ? 
ATOM   12   C CG2 . VAL A 1 2   ? -33.213 1.811   10.909  1.000 111.365 0 2   VAL HHH CG2 1 ? 
ATOM   13   N N   . LEU A 1 3   ? -29.182 1.217   13.497  1.000 97.796  0 3   LEU HHH N   1 ? 
ATOM   14   C CA  . LEU A 1 3   ? -28.050 0.490   14.122  1.000 94.820  0 3   LEU HHH CA  1 ? 
ATOM   15   C C   . LEU A 1 3   ? -28.373 0.181   15.587  1.000 91.354  0 3   LEU HHH C   1 ? 
ATOM   16   O O   . LEU A 1 3   ? -28.659 1.112   16.345  1.000 83.158  0 3   LEU HHH O   1 ? 
ATOM   17   C CB  . LEU A 1 3   ? -26.791 1.349   14.003  1.000 101.019 0 3   LEU HHH CB  1 ? 
ATOM   18   C CG  . LEU A 1 3   ? -25.567 0.823   14.750  1.000 108.904 0 3   LEU HHH CG  1 ? 
ATOM   19   C CD1 . LEU A 1 3   ? -24.881 -0.288  13.964  1.000 111.796 0 3   LEU HHH CD1 1 ? 
ATOM   20   C CD2 . LEU A 1 3   ? -24.596 1.956   15.038  1.000 113.543 0 3   LEU HHH CD2 1 ? 
ATOM   21   N N   . LEU A 1 4   ? -28.313 -1.093  15.966  1.000 96.702  0 4   LEU HHH N   1 ? 
ATOM   22   C CA  . LEU A 1 4   ? -28.356 -1.530  17.383  1.000 94.132  0 4   LEU HHH CA  1 ? 
ATOM   23   C C   . LEU A 1 4   ? -26.938 -1.929  17.796  1.000 93.914  0 4   LEU HHH C   1 ? 
ATOM   24   O O   . LEU A 1 4   ? -26.298 -2.710  17.052  1.000 92.326  0 4   LEU HHH O   1 ? 
ATOM   25   C CB  . LEU A 1 4   ? -29.328 -2.700  17.524  1.000 100.647 0 4   LEU HHH CB  1 ? 
ATOM   26   C CG  . LEU A 1 4   ? -30.782 -2.404  17.170  1.000 97.830  0 4   LEU HHH CG  1 ? 
ATOM   27   C CD1 . LEU A 1 4   ? -31.640 -3.630  17.431  1.000 98.946  0 4   LEU HHH CD1 1 ? 
ATOM   28   C CD2 . LEU A 1 4   ? -31.306 -1.218  17.958  1.000 94.220  0 4   LEU HHH CD2 1 ? 
ATOM   29   N N   . LEU A 1 5   ? -26.455 -1.393  18.919  1.000 90.149  0 5   LEU HHH N   1 ? 
ATOM   30   C CA  . LEU A 1 5   ? -25.064 -1.609  19.382  1.000 89.987  0 5   LEU HHH CA  1 ? 
ATOM   31   C C   . LEU A 1 5   ? -25.085 -2.218  20.780  1.000 90.645  0 5   LEU HHH C   1 ? 
ATOM   32   O O   . LEU A 1 5   ? -25.696 -1.619  21.679  1.000 100.891 0 5   LEU HHH O   1 ? 
ATOM   33   C CB  . LEU A 1 5   ? -24.295 -0.286  19.361  1.000 95.867  0 5   LEU HHH CB  1 ? 
ATOM   34   C CG  . LEU A 1 5   ? -22.797 -0.434  19.091  1.000 101.422 0 5   LEU HHH CG  1 ? 
ATOM   35   C CD1 . LEU A 1 5   ? -22.546 -0.764  17.625  1.000 101.788 0 5   LEU HHH CD1 1 ? 
ATOM   36   C CD2 . LEU A 1 5   ? -22.038 0.819   19.498  1.000 106.959 0 5   LEU HHH CD2 1 ? 
ATOM   37   N N   . GLN A 1 6   ? -24.419 -3.361  20.941  1.000 84.788  0 6   GLN HHH N   1 ? 
ATOM   38   C CA  . GLN A 1 6   ? -24.315 -4.107  22.218  1.000 88.863  0 6   GLN HHH CA  1 ? 
ATOM   39   C C   . GLN A 1 6   ? -22.857 -4.106  22.676  1.000 87.615  0 6   GLN HHH C   1 ? 
ATOM   40   O O   . GLN A 1 6   ? -22.002 -3.815  21.837  1.000 94.720  0 6   GLN HHH O   1 ? 
ATOM   41   C CB  . GLN A 1 6   ? -24.809 -5.537  22.017  1.000 87.882  0 6   GLN HHH CB  1 ? 
ATOM   42   C CG  . GLN A 1 6   ? -26.260 -5.625  21.580  1.000 80.045  0 6   GLN HHH CG  1 ? 
ATOM   43   C CD  . GLN A 1 6   ? -26.722 -7.059  21.516  1.000 80.500  0 6   GLN HHH CD  1 ? 
ATOM   44   O OE1 . GLN A 1 6   ? -27.305 -7.511  20.530  1.000 75.296  0 6   GLN HHH OE1 1 ? 
ATOM   45   N NE2 . GLN A 1 6   ? -26.470 -7.791  22.588  1.000 83.021  0 6   GLN HHH NE2 1 ? 
ATOM   46   N N   . SER A 1 7   ? -22.592 -4.442  23.943  1.000 90.169  0 7   SER HHH N   1 ? 
ATOM   47   C CA  . SER A 1 7   ? -21.221 -4.552  24.511  1.000 92.307  0 7   SER HHH CA  1 ? 
ATOM   48   C C   . SER A 1 7   ? -20.485 -5.741  23.875  1.000 87.613  0 7   SER HHH C   1 ? 
ATOM   49   O O   . SER A 1 7   ? -21.131 -6.547  23.193  1.000 87.398  0 7   SER HHH O   1 ? 
ATOM   50   C CB  . SER A 1 7   ? -21.259 -4.654  26.019  1.000 97.986  0 7   SER HHH CB  1 ? 
ATOM   51   O OG  . SER A 1 7   ? -21.880 -5.859  26.435  1.000 100.072 0 7   SER HHH OG  1 ? 
ATOM   52   N N   . GLY A 1 8   ? -19.168 -5.827  24.073  1.000 94.048  0 8   GLY HHH N   1 ? 
ATOM   53   C CA  . GLY A 1 8   ? -18.323 -6.934  23.582  1.000 93.838  0 8   GLY HHH CA  1 ? 
ATOM   54   C C   . GLY A 1 8   ? -18.431 -8.163  24.482  1.000 92.736  0 8   GLY HHH C   1 ? 
ATOM   55   O O   . GLY A 1 8   ? -19.315 -8.224  25.336  1.000 90.801  0 8   GLY HHH O   1 ? 
ATOM   56   N N   . PRO A 1 9   ? -17.529 -9.164  24.338  1.000 88.793  0 9   PRO HHH N   1 ? 
ATOM   57   C CA  . PRO A 1 9   ? -17.647 -10.423 25.075  1.000 89.113  0 9   PRO HHH CA  1 ? 
ATOM   58   C C   . PRO A 1 9   ? -17.375 -10.254 26.579  1.000 92.783  0 9   PRO HHH C   1 ? 
ATOM   59   O O   . PRO A 1 9   ? -16.371 -9.681  26.945  1.000 108.291 0 9   PRO HHH O   1 ? 
ATOM   60   C CB  . PRO A 1 9   ? -16.603 -11.332 24.411  1.000 91.677  0 9   PRO HHH CB  1 ? 
ATOM   61   C CG  . PRO A 1 9   ? -15.562 -10.366 23.882  1.000 97.862  0 9   PRO HHH CG  1 ? 
ATOM   62   C CD  . PRO A 1 9   ? -16.334 -9.122  23.485  1.000 92.213  0 9   PRO HHH CD  1 ? 
ATOM   63   N N   . GLU A 1 10  ? -18.291 -10.744 27.413  1.000 91.493  0 10  GLU HHH N   1 ? 
ATOM   64   C CA  . GLU A 1 10  ? -18.225 -10.639 28.893  1.000 87.011  0 10  GLU HHH CA  1 ? 
ATOM   65   C C   . GLU A 1 10  ? -17.819 -11.995 29.468  1.000 79.810  0 10  GLU HHH C   1 ? 
ATOM   66   O O   . GLU A 1 10  ? -18.468 -13.003 29.154  1.000 66.032  0 10  GLU HHH O   1 ? 
ATOM   67   C CB  . GLU A 1 10  ? -19.579 -10.210 29.458  1.000 96.356  0 10  GLU HHH CB  1 ? 
ATOM   68   C CG  . GLU A 1 10  ? -19.979 -8.801  29.067  1.000 109.581 0 10  GLU HHH CG  1 ? 
ATOM   69   C CD  . GLU A 1 10  ? -19.270 -7.712  29.852  1.000 115.391 0 10  GLU HHH CD  1 ? 
ATOM   70   O OE1 . GLU A 1 10  ? -19.509 -7.609  31.069  1.000 113.000 0 10  GLU HHH OE1 1 ? 
ATOM   71   O OE2 . GLU A 1 10  ? -18.469 -6.980  29.242  1.000 129.805 0 10  GLU HHH OE2 1 ? 
ATOM   72   N N   . LEU A 1 11  ? -16.766 -12.024 30.277  1.000 84.229  0 11  LEU HHH N   1 ? 
ATOM   73   C CA  . LEU A 1 11  ? -16.507 -13.167 31.183  1.000 84.469  0 11  LEU HHH CA  1 ? 
ATOM   74   C C   . LEU A 1 11  ? -17.082 -12.794 32.547  1.000 78.487  0 11  LEU HHH C   1 ? 
ATOM   75   O O   . LEU A 1 11  ? -16.845 -11.666 32.994  1.000 71.680  0 11  LEU HHH O   1 ? 
ATOM   76   C CB  . LEU A 1 11  ? -15.009 -13.463 31.253  1.000 86.565  0 11  LEU HHH CB  1 ? 
ATOM   77   C CG  . LEU A 1 11  ? -14.631 -14.656 32.131  1.000 94.842  0 11  LEU HHH CG  1 ? 
ATOM   78   C CD1 . LEU A 1 11  ? -15.252 -15.950 31.622  1.000 98.736  0 11  LEU HHH CD1 1 ? 
ATOM   79   C CD2 . LEU A 1 11  ? -13.123 -14.805 32.213  1.000 98.329  0 11  LEU HHH CD2 1 ? 
ATOM   80   N N   . VAL A 1 12  ? -17.841 -13.695 33.159  1.000 76.603  0 12  VAL HHH N   1 ? 
ATOM   81   C CA  . VAL A 1 12  ? -18.522 -13.397 34.445  1.000 80.097  0 12  VAL HHH CA  1 ? 
ATOM   82   C C   . VAL A 1 12  ? -18.638 -14.671 35.304  1.000 81.230  0 12  VAL HHH C   1 ? 
ATOM   83   O O   . VAL A 1 12  ? -18.712 -15.795 34.751  1.000 76.814  0 12  VAL HHH O   1 ? 
ATOM   84   C CB  . VAL A 1 12  ? -19.870 -12.722 34.157  1.000 80.397  0 12  VAL HHH CB  1 ? 
ATOM   85   C CG1 . VAL A 1 12  ? -20.894 -13.748 33.698  1.000 81.318  0 12  VAL HHH CG1 1 ? 
ATOM   86   C CG2 . VAL A 1 12  ? -20.346 -11.929 35.369  1.000 87.796  0 12  VAL HHH CG2 1 ? 
ATOM   87   N N   . LYS A 1 13  ? -18.590 -14.488 36.626  1.000 77.612  0 13  LYS HHH N   1 ? 
ATOM   88   C CA  . LYS A 1 13  ? -18.490 -15.573 37.633  1.000 74.427  0 13  LYS HHH CA  1 ? 
ATOM   89   C C   . LYS A 1 13  ? -19.888 -16.123 37.886  1.000 74.864  0 13  LYS HHH C   1 ? 
ATOM   90   O O   . LYS A 1 13  ? -20.859 -15.369 37.892  1.000 73.990  0 13  LYS HHH O   1 ? 
ATOM   91   C CB  . LYS A 1 13  ? -17.874 -14.996 38.912  1.000 80.690  0 13  LYS HHH CB  1 ? 
ATOM   92   C CG  . LYS A 1 13  ? -17.593 -15.985 40.034  1.000 88.463  0 13  LYS HHH CG  1 ? 
ATOM   93   C CD  . LYS A 1 13  ? -16.664 -15.429 41.126  1.000 94.765  0 13  LYS HHH CD  1 ? 
ATOM   94   C CE  . LYS A 1 13  ? -17.324 -14.463 42.083  1.000 93.006  0 13  LYS HHH CE  1 ? 
ATOM   95   N NZ  . LYS A 1 13  ? -18.490 -15.101 42.741  1.000 110.838 0 13  LYS HHH NZ  1 ? 
ATOM   96   N N   . PRO A 1 14  ? -20.049 -17.445 38.109  1.000 71.119  0 14  PRO HHH N   1 ? 
ATOM   97   C CA  . PRO A 1 14  ? -21.336 -17.987 38.543  1.000 74.233  0 14  PRO HHH CA  1 ? 
ATOM   98   C C   . PRO A 1 14  ? -21.833 -17.294 39.823  1.000 75.951  0 14  PRO HHH C   1 ? 
ATOM   99   O O   . PRO A 1 14  ? -21.049 -17.114 40.755  1.000 81.153  0 14  PRO HHH O   1 ? 
ATOM   100  C CB  . PRO A 1 14  ? -21.059 -19.485 38.764  1.000 70.491  0 14  PRO HHH CB  1 ? 
ATOM   101  C CG  . PRO A 1 14  ? -19.865 -19.761 37.877  1.000 71.589  0 14  PRO HHH CG  1 ? 
ATOM   102  C CD  . PRO A 1 14  ? -19.036 -18.490 37.930  1.000 70.361  0 14  PRO HHH CD  1 ? 
ATOM   103  N N   . GLY A 1 15  ? -23.107 -16.892 39.821  1.000 75.388  0 15  GLY HHH N   1 ? 
ATOM   104  C CA  . GLY A 1 15  ? -23.812 -16.364 41.000  1.000 73.033  0 15  GLY HHH CA  1 ? 
ATOM   105  C C   . GLY A 1 15  ? -23.772 -14.851 41.060  1.000 77.556  0 15  GLY HHH C   1 ? 
ATOM   106  O O   . GLY A 1 15  ? -24.201 -14.311 42.086  1.000 96.252  0 15  GLY HHH O   1 ? 
ATOM   107  N N   . THR A 1 16  ? -23.311 -14.188 39.997  1.000 79.420  0 16  THR HHH N   1 ? 
ATOM   108  C CA  . THR A 1 16  ? -23.291 -12.706 39.870  1.000 81.794  0 16  THR HHH CA  1 ? 
ATOM   109  C C   . THR A 1 16  ? -24.389 -12.279 38.880  1.000 83.472  0 16  THR HHH C   1 ? 
ATOM   110  O O   . THR A 1 16  ? -25.386 -13.024 38.752  1.000 74.193  0 16  THR HHH O   1 ? 
ATOM   111  C CB  . THR A 1 16  ? -21.873 -12.225 39.535  1.000 85.992  0 16  THR HHH CB  1 ? 
ATOM   112  O OG1 . THR A 1 16  ? -21.515 -12.710 38.241  1.000 89.805  0 16  THR HHH OG1 1 ? 
ATOM   113  C CG2 . THR A 1 16  ? -20.852 -12.683 40.556  1.000 84.800  0 16  THR HHH CG2 1 ? 
ATOM   114  N N   . SER A 1 17  ? -24.230 -11.115 38.230  1.000 89.709  0 17  SER HHH N   1 ? 
ATOM   115  C CA  . SER A 1 17  ? -25.297 -10.415 37.463  1.000 87.170  0 17  SER HHH CA  1 ? 
ATOM   116  C C   . SER A 1 17  ? -24.688 -9.447  36.439  1.000 81.669  0 17  SER HHH C   1 ? 
ATOM   117  O O   . SER A 1 17  ? -24.088 -8.448  36.852  1.000 93.517  0 17  SER HHH O   1 ? 
ATOM   118  C CB  . SER A 1 17  ? -26.238 -9.695  38.406  1.000 86.199  0 17  SER HHH CB  1 ? 
ATOM   119  O OG  . SER A 1 17  ? -27.483 -9.413  37.782  1.000 93.406  0 17  SER HHH OG  1 ? 
ATOM   120  N N   . VAL A 1 18  ? -24.886 -9.718  35.150  1.000 80.329  0 18  VAL HHH N   1 ? 
ATOM   121  C CA  . VAL A 1 18  ? -24.388 -8.889  34.011  1.000 77.852  0 18  VAL HHH CA  1 ? 
ATOM   122  C C   . VAL A 1 18  ? -25.542 -8.019  33.525  1.000 69.164  0 18  VAL HHH C   1 ? 
ATOM   123  O O   . VAL A 1 18  ? -26.614 -8.596  33.353  1.000 68.795  0 18  VAL HHH O   1 ? 
ATOM   124  C CB  . VAL A 1 18  ? -23.881 -9.779  32.857  1.000 82.264  0 18  VAL HHH CB  1 ? 
ATOM   125  C CG1 . VAL A 1 18  ? -23.345 -8.948  31.703  1.000 87.586  0 18  VAL HHH CG1 1 ? 
ATOM   126  C CG2 . VAL A 1 18  ? -22.829 -10.774 33.309  1.000 83.693  0 18  VAL HHH CG2 1 ? 
ATOM   127  N N   . LYS A 1 19  ? -25.324 -6.715  33.303  1.000 71.560  0 19  LYS HHH N   1 ? 
ATOM   128  C CA  . LYS A 1 19  ? -26.312 -5.794  32.663  1.000 70.775  0 19  LYS HHH CA  1 ? 
ATOM   129  C C   . LYS A 1 19  ? -25.797 -5.492  31.257  1.000 75.263  0 19  LYS HHH C   1 ? 
ATOM   130  O O   . LYS A 1 19  ? -24.755 -4.825  31.150  1.000 85.866  0 19  LYS HHH O   1 ? 
ATOM   131  C CB  . LYS A 1 19  ? -26.553 -4.499  33.451  1.000 58.997  0 19  LYS HHH CB  1 ? 
ATOM   132  N N   . ILE A 1 20  ? -26.500 -5.992  30.236  1.000 77.929  0 20  ILE HHH N   1 ? 
ATOM   133  C CA  . ILE A 1 20  ? -26.122 -5.883  28.798  1.000 76.265  0 20  ILE HHH CA  1 ? 
ATOM   134  C C   . ILE A 1 20  ? -26.818 -4.673  28.186  1.000 74.598  0 20  ILE HHH C   1 ? 
ATOM   135  O O   . ILE A 1 20  ? -28.049 -4.631  28.148  1.000 67.044  0 20  ILE HHH O   1 ? 
ATOM   136  C CB  . ILE A 1 20  ? -26.500 -7.169  28.043  1.000 81.392  0 20  ILE HHH CB  1 ? 
ATOM   137  C CG1 . ILE A 1 20  ? -25.871 -8.398  28.699  1.000 82.006  0 20  ILE HHH CG1 1 ? 
ATOM   138  C CG2 . ILE A 1 20  ? -26.134 -7.063  26.565  1.000 89.843  0 20  ILE HHH CG2 1 ? 
ATOM   139  C CD1 . ILE A 1 20  ? -26.302 -9.713  28.092  1.000 80.173  0 20  ILE HHH CD1 1 ? 
ATOM   140  N N   . PRO A 1 21  ? -26.054 -3.702  27.627  1.000 76.003  0 21  PRO HHH N   1 ? 
ATOM   141  C CA  . PRO A 1 21  ? -26.637 -2.578  26.895  1.000 76.497  0 21  PRO HHH CA  1 ? 
ATOM   142  C C   . PRO A 1 21  ? -27.088 -2.913  25.464  1.000 84.854  0 21  PRO HHH C   1 ? 
ATOM   143  O O   . PRO A 1 21  ? -26.895 -4.040  25.013  1.000 95.619  0 21  PRO HHH O   1 ? 
ATOM   144  C CB  . PRO A 1 21  ? -25.465 -1.594  26.846  1.000 73.873  0 21  PRO HHH CB  1 ? 
ATOM   145  C CG  . PRO A 1 21  ? -24.262 -2.489  26.721  1.000 75.955  0 21  PRO HHH CG  1 ? 
ATOM   146  C CD  . PRO A 1 21  ? -24.582 -3.656  27.630  1.000 76.028  0 21  PRO HHH CD  1 ? 
ATOM   147  N N   . CYS A 1 22  ? -27.687 -1.922  24.798  1.000 89.194  0 22  CYS HHH N   1 ? 
ATOM   148  C CA  . CYS A 1 22  ? -28.153 -1.959  23.384  1.000 85.384  0 22  CYS HHH CA  1 ? 
ATOM   149  C C   . CYS A 1 22  ? -28.457 -0.526  22.922  1.000 80.834  0 22  CYS HHH C   1 ? 
ATOM   150  O O   . CYS A 1 22  ? -29.588 -0.073  23.179  1.000 77.953  0 22  CYS HHH O   1 ? 
ATOM   151  C CB  . CYS A 1 22  ? -29.380 -2.855  23.236  1.000 86.617  0 22  CYS HHH CB  1 ? 
ATOM   152  S SG  . CYS A 1 22  ? -29.941 -3.028  21.520  1.000 96.552  0 22  CYS HHH SG  1 ? 
ATOM   153  N N   . LYS A 1 23  ? -27.489 0.156   22.285  1.000 79.788  0 23  LYS HHH N   1 ? 
ATOM   154  C CA  . LYS A 1 23  ? -27.577 1.594   21.878  1.000 78.164  0 23  LYS HHH CA  1 ? 
ATOM   155  C C   . LYS A 1 23  ? -28.302 1.709   20.531  1.000 78.775  0 23  LYS HHH C   1 ? 
ATOM   156  O O   . LYS A 1 23  ? -27.672 1.413   19.494  1.000 80.030  0 23  LYS HHH O   1 ? 
ATOM   157  C CB  . LYS A 1 23  ? -26.192 2.249   21.787  1.000 70.443  0 23  LYS HHH CB  1 ? 
ATOM   158  N N   . ALA A 1 24  ? -29.567 2.146   20.551  1.000 82.949  0 24  ALA HHH N   1 ? 
ATOM   159  C CA  . ALA A 1 24  ? -30.443 2.281   19.361  1.000 89.105  0 24  ALA HHH CA  1 ? 
ATOM   160  C C   . ALA A 1 24  ? -30.244 3.643   18.692  1.000 86.528  0 24  ALA HHH C   1 ? 
ATOM   161  O O   . ALA A 1 24  ? -30.117 4.647   19.403  1.000 91.454  0 24  ALA HHH O   1 ? 
ATOM   162  C CB  . ALA A 1 24  ? -31.877 2.102   19.765  1.000 98.358  0 24  ALA HHH CB  1 ? 
ATOM   163  N N   . SER A 1 25  ? -30.268 3.672   17.364  1.000 83.960  0 25  SER HHH N   1 ? 
ATOM   164  C CA  . SER A 1 25  ? -29.900 4.862   16.560  1.000 87.306  0 25  SER HHH CA  1 ? 
ATOM   165  C C   . SER A 1 25  ? -30.386 4.703   15.114  1.000 86.068  0 25  SER HHH C   1 ? 
ATOM   166  O O   . SER A 1 25  ? -30.499 3.548   14.638  1.000 80.902  0 25  SER HHH O   1 ? 
ATOM   167  C CB  . SER A 1 25  ? -28.412 5.085   16.627  1.000 89.343  0 25  SER HHH CB  1 ? 
ATOM   168  O OG  . SER A 1 25  ? -27.704 3.934   16.186  1.000 92.336  0 25  SER HHH OG  1 ? 
ATOM   169  N N   . GLY A 1 26  ? -30.661 5.836   14.461  1.000 84.018  0 26  GLY HHH N   1 ? 
ATOM   170  C CA  . GLY A 1 26  ? -31.104 5.921   13.058  1.000 84.916  0 26  GLY HHH CA  1 ? 
ATOM   171  C C   . GLY A 1 26  ? -32.603 5.709   12.912  1.000 85.025  0 26  GLY HHH C   1 ? 
ATOM   172  O O   . GLY A 1 26  ? -33.066 5.535   11.755  1.000 83.300  0 26  GLY HHH O   1 ? 
ATOM   173  N N   . TYR A 1 27  ? -33.335 5.685   14.033  1.000 89.611  0 27  TYR HHH N   1 ? 
ATOM   174  C CA  . TYR A 1 27  ? -34.816 5.533   14.071  1.000 96.767  0 27  TYR HHH CA  1 ? 
ATOM   175  C C   . TYR A 1 27  ? -35.354 6.166   15.363  1.000 96.489  0 27  TYR HHH C   1 ? 
ATOM   176  O O   . TYR A 1 27  ? -34.557 6.592   16.216  1.000 98.749  0 27  TYR HHH O   1 ? 
ATOM   177  C CB  . TYR A 1 27  ? -35.207 4.060   13.875  1.000 96.668  0 27  TYR HHH CB  1 ? 
ATOM   178  C CG  . TYR A 1 27  ? -35.007 3.155   15.065  1.000 97.053  0 27  TYR HHH CG  1 ? 
ATOM   179  C CD1 . TYR A 1 27  ? -33.752 2.687   15.425  1.000 98.879  0 27  TYR HHH CD1 1 ? 
ATOM   180  C CD2 . TYR A 1 27  ? -36.089 2.734   15.817  1.000 99.440  0 27  TYR HHH CD2 1 ? 
ATOM   181  C CE1 . TYR A 1 27  ? -33.579 1.851   16.520  1.000 104.333 0 27  TYR HHH CE1 1 ? 
ATOM   182  C CE2 . TYR A 1 27  ? -35.933 1.904   16.914  1.000 106.771 0 27  TYR HHH CE2 1 ? 
ATOM   183  C CZ  . TYR A 1 27  ? -34.677 1.456   17.269  1.000 103.471 0 27  TYR HHH CZ  1 ? 
ATOM   184  O OH  . TYR A 1 27  ? -34.584 0.629   18.352  1.000 104.320 0 27  TYR HHH OH  1 ? 
ATOM   185  N N   . THR A 1 28  ? -36.678 6.238   15.495  1.000 108.978 0 28  THR HHH N   1 ? 
ATOM   186  C CA  . THR A 1 28  ? -37.390 6.912   16.618  1.000 126.243 0 28  THR HHH CA  1 ? 
ATOM   187  C C   . THR A 1 28  ? -36.957 6.327   17.973  1.000 129.948 0 28  THR HHH C   1 ? 
ATOM   188  O O   . THR A 1 28  ? -36.814 7.110   18.930  1.000 132.282 0 28  THR HHH O   1 ? 
ATOM   189  C CB  . THR A 1 28  ? -38.909 6.814   16.425  1.000 130.392 0 28  THR HHH CB  1 ? 
ATOM   190  O OG1 . THR A 1 28  ? -39.201 5.486   15.988  1.000 135.404 0 28  THR HHH OG1 1 ? 
ATOM   191  C CG2 . THR A 1 28  ? -39.452 7.808   15.421  1.000 127.111 0 28  THR HHH CG2 1 ? 
ATOM   192  N N   . PHE A 1 29  ? -36.779 5.003   18.049  1.000 132.358 0 29  PHE HHH N   1 ? 
ATOM   193  C CA  . PHE A 1 29  ? -36.411 4.225   19.266  1.000 124.294 0 29  PHE HHH CA  1 ? 
ATOM   194  C C   . PHE A 1 29  ? -37.633 4.069   20.171  1.000 125.706 0 29  PHE HHH C   1 ? 
ATOM   195  O O   . PHE A 1 29  ? -38.075 2.929   20.377  1.000 142.903 0 29  PHE HHH O   1 ? 
ATOM   196  C CB  . PHE A 1 29  ? -35.266 4.853   20.066  1.000 115.316 0 29  PHE HHH CB  1 ? 
ATOM   197  C CG  . PHE A 1 29  ? -35.064 4.217   21.418  1.000 117.717 0 29  PHE HHH CG  1 ? 
ATOM   198  C CD1 . PHE A 1 29  ? -34.627 2.905   21.534  1.000 112.457 0 29  PHE HHH CD1 1 ? 
ATOM   199  C CD2 . PHE A 1 29  ? -35.334 4.920   22.583  1.000 128.508 0 29  PHE HHH CD2 1 ? 
ATOM   200  C CE1 . PHE A 1 29  ? -34.446 2.317   22.778  1.000 107.367 0 29  PHE HHH CE1 1 ? 
ATOM   201  C CE2 . PHE A 1 29  ? -35.150 4.332   23.828  1.000 127.807 0 29  PHE HHH CE2 1 ? 
ATOM   202  C CZ  . PHE A 1 29  ? -34.710 3.030   23.922  1.000 111.409 0 29  PHE HHH CZ  1 ? 
ATOM   203  N N   . THR A 1 30  ? -38.164 5.177   20.695  1.000 127.481 0 30  THR HHH N   1 ? 
ATOM   204  C CA  . THR A 1 30  ? -39.342 5.183   21.609  1.000 123.808 0 30  THR HHH CA  1 ? 
ATOM   205  C C   . THR A 1 30  ? -40.609 4.694   20.875  1.000 119.362 0 30  THR HHH C   1 ? 
ATOM   206  O O   . THR A 1 30  ? -41.645 4.570   21.550  1.000 117.286 0 30  THR HHH O   1 ? 
ATOM   207  C CB  . THR A 1 30  ? -39.558 6.564   22.254  1.000 119.844 0 30  THR HHH CB  1 ? 
ATOM   208  O OG1 . THR A 1 30  ? -39.651 7.530   21.209  1.000 121.160 0 30  THR HHH OG1 1 ? 
ATOM   209  C CG2 . THR A 1 30  ? -38.456 6.981   23.204  1.000 113.993 0 30  THR HHH CG2 1 ? 
ATOM   210  N N   . ASP A 1 31  ? -40.551 4.418   19.563  1.000 110.568 0 31  ASP HHH N   1 ? 
ATOM   211  C CA  . ASP A 1 31  ? -41.730 3.997   18.756  1.000 109.924 0 31  ASP HHH CA  1 ? 
ATOM   212  C C   . ASP A 1 31  ? -41.748 2.475   18.545  1.000 111.445 0 31  ASP HHH C   1 ? 
ATOM   213  O O   . ASP A 1 31  ? -42.838 1.953   18.237  1.000 113.218 0 31  ASP HHH O   1 ? 
ATOM   214  C CB  . ASP A 1 31  ? -41.767 4.719   17.408  1.000 106.605 0 31  ASP HHH CB  1 ? 
ATOM   215  N N   . TYR A 1 32  ? -40.613 1.783   18.694  1.000 106.680 0 32  TYR HHH N   1 ? 
ATOM   216  C CA  . TYR A 1 32  ? -40.488 0.327   18.409  1.000 99.303  0 32  TYR HHH CA  1 ? 
ATOM   217  C C   . TYR A 1 32  ? -40.079 -0.457  19.655  1.000 91.730  0 32  TYR HHH C   1 ? 
ATOM   218  O O   . TYR A 1 32  ? -39.129 -0.037  20.334  1.000 99.472  0 32  TYR HHH O   1 ? 
ATOM   219  C CB  . TYR A 1 32  ? -39.392 0.045   17.387  1.000 104.660 0 32  TYR HHH CB  1 ? 
ATOM   220  C CG  . TYR A 1 32  ? -39.628 0.549   15.989  1.000 116.127 0 32  TYR HHH CG  1 ? 
ATOM   221  C CD1 . TYR A 1 32  ? -39.395 1.874   15.656  1.000 123.705 0 32  TYR HHH CD1 1 ? 
ATOM   222  C CD2 . TYR A 1 32  ? -39.997 -0.321  14.978  1.000 120.868 0 32  TYR HHH CD2 1 ? 
ATOM   223  C CE1 . TYR A 1 32  ? -39.558 2.332   14.360  1.000 126.037 0 32  TYR HHH CE1 1 ? 
ATOM   224  C CE2 . TYR A 1 32  ? -40.176 0.121   13.678  1.000 135.179 0 32  TYR HHH CE2 1 ? 
ATOM   225  C CZ  . TYR A 1 32  ? -39.946 1.450   13.366  1.000 137.336 0 32  TYR HHH CZ  1 ? 
ATOM   226  O OH  . TYR A 1 32  ? -40.118 1.892   12.085  1.000 159.730 0 32  TYR HHH OH  1 ? 
ATOM   227  N N   . ASN A 1 33  ? -40.695 -1.620  19.875  1.000 80.916  0 33  ASN HHH N   1 ? 
ATOM   228  C CA  . ASN A 1 33  ? -40.319 -2.562  20.964  1.000 77.255  0 33  ASN HHH CA  1 ? 
ATOM   229  C C   . ASN A 1 33  ? -38.920 -3.121  20.684  1.000 71.660  0 33  ASN HHH C   1 ? 
ATOM   230  O O   . ASN A 1 33  ? -38.540 -3.236  19.502  1.000 67.485  0 33  ASN HHH O   1 ? 
ATOM   231  C CB  . ASN A 1 33  ? -41.350 -3.680  21.144  1.000 79.786  0 33  ASN HHH CB  1 ? 
ATOM   232  C CG  . ASN A 1 33  ? -42.587 -3.178  21.837  1.000 87.343  0 33  ASN HHH CG  1 ? 
ATOM   233  O OD1 . ASN A 1 33  ? -43.236 -3.891  22.593  1.000 83.923  0 33  ASN HHH OD1 1 ? 
ATOM   234  N ND2 . ASN A 1 33  ? -42.878 -1.913  21.608  1.000 106.467 0 33  ASN HHH ND2 1 ? 
ATOM   235  N N   . VAL A 1 34  ? -38.181 -3.454  21.739  1.000 65.812  0 34  VAL HHH N   1 ? 
ATOM   236  C CA  . VAL A 1 34  ? -36.857 -4.121  21.630  1.000 72.053  0 34  VAL HHH CA  1 ? 
ATOM   237  C C   . VAL A 1 34  ? -36.985 -5.529  22.211  1.000 72.872  0 34  VAL HHH C   1 ? 
ATOM   238  O O   . VAL A 1 34  ? -37.181 -5.635  23.424  1.000 72.022  0 34  VAL HHH O   1 ? 
ATOM   239  C CB  . VAL A 1 34  ? -35.763 -3.306  22.338  1.000 78.161  0 34  VAL HHH CB  1 ? 
ATOM   240  C CG1 . VAL A 1 34  ? -34.398 -3.956  22.182  1.000 79.134  0 34  VAL HHH CG1 1 ? 
ATOM   241  C CG2 . VAL A 1 34  ? -35.734 -1.870  21.834  1.000 87.473  0 34  VAL HHH CG2 1 ? 
ATOM   242  N N   . ASP A 1 35  ? -36.863 -6.566  21.374  1.000 75.451  0 35  ASP HHH N   1 ? 
ATOM   243  C CA  . ASP A 1 35  ? -36.905 -7.986  21.818  1.000 70.532  0 35  ASP HHH CA  1 ? 
ATOM   244  C C   . ASP A 1 35  ? -35.496 -8.474  22.155  1.000 59.370  0 35  ASP HHH C   1 ? 
ATOM   245  O O   . ASP A 1 35  ? -34.532 -7.934  21.627  1.000 51.678  0 35  ASP HHH O   1 ? 
ATOM   246  C CB  . ASP A 1 35  ? -37.554 -8.870  20.762  1.000 77.845  0 35  ASP HHH CB  1 ? 
ATOM   247  C CG  . ASP A 1 35  ? -39.042 -8.616  20.609  1.000 97.133  0 35  ASP HHH CG  1 ? 
ATOM   248  O OD1 . ASP A 1 35  ? -39.624 -7.958  21.481  1.000 123.049 0 35  ASP HHH OD1 1 ? 
ATOM   249  O OD2 . ASP A 1 35  ? -39.612 -9.093  19.623  1.000 113.337 0 35  ASP HHH OD2 1 ? 
ATOM   250  N N   . TRP A 1 36  ? -35.398 -9.473  23.026  1.000 58.979  0 36  TRP HHH N   1 ? 
ATOM   251  C CA  . TRP A 1 36  ? -34.115 -10.100 23.428  1.000 59.929  0 36  TRP HHH CA  1 ? 
ATOM   252  C C   . TRP A 1 36  ? -34.169 -11.605 23.144  1.000 54.403  0 36  TRP HHH C   1 ? 
ATOM   253  O O   . TRP A 1 36  ? -35.217 -12.223 23.350  1.000 44.736  0 36  TRP HHH O   1 ? 
ATOM   254  C CB  . TRP A 1 36  ? -33.803 -9.790  24.895  1.000 59.791  0 36  TRP HHH CB  1 ? 
ATOM   255  C CG  . TRP A 1 36  ? -33.307 -8.394  25.102  1.000 64.758  0 36  TRP HHH CG  1 ? 
ATOM   256  C CD1 . TRP A 1 36  ? -34.048 -7.276  25.361  1.000 64.672  0 36  TRP HHH CD1 1 ? 
ATOM   257  C CD2 . TRP A 1 36  ? -31.942 -7.958  25.048  1.000 64.115  0 36  TRP HHH CD2 1 ? 
ATOM   258  N NE1 . TRP A 1 36  ? -33.237 -6.187  25.501  1.000 62.010  0 36  TRP HHH NE1 1 ? 
ATOM   259  C CE2 . TRP A 1 36  ? -31.941 -6.571  25.306  1.000 61.768  0 36  TRP HHH CE2 1 ? 
ATOM   260  C CE3 . TRP A 1 36  ? -30.727 -8.603  24.809  1.000 66.253  0 36  TRP HHH CE3 1 ? 
ATOM   261  C CZ2 . TRP A 1 36  ? -30.773 -5.818  25.334  1.000 66.302  0 36  TRP HHH CZ2 1 ? 
ATOM   262  C CZ3 . TRP A 1 36  ? -29.569 -7.861  24.843  1.000 71.142  0 36  TRP HHH CZ3 1 ? 
ATOM   263  C CH2 . TRP A 1 36  ? -29.594 -6.486  25.104  1.000 71.479  0 36  TRP HHH CH2 1 ? 
ATOM   264  N N   . VAL A 1 37  ? -33.057 -12.165 22.690  1.000 57.494  0 37  VAL HHH N   1 ? 
ATOM   265  C CA  . VAL A 1 37  ? -32.979 -13.566 22.191  1.000 68.723  0 37  VAL HHH CA  1 ? 
ATOM   266  C C   . VAL A 1 37  ? -31.642 -14.184 22.617  1.000 69.039  0 37  VAL HHH C   1 ? 
ATOM   267  O O   . VAL A 1 37  ? -30.595 -13.522 22.467  1.000 66.617  0 37  VAL HHH O   1 ? 
ATOM   268  C CB  . VAL A 1 37  ? -33.166 -13.597 20.665  1.000 71.586  0 37  VAL HHH CB  1 ? 
ATOM   269  C CG1 . VAL A 1 37  ? -32.813 -14.948 20.086  1.000 71.963  0 37  VAL HHH CG1 1 ? 
ATOM   270  C CG2 . VAL A 1 37  ? -34.573 -13.183 20.274  1.000 77.344  0 37  VAL HHH CG2 1 ? 
ATOM   271  N N   . LYS A 1 38  ? -31.689 -15.421 23.119  1.000 65.371  0 38  LYS HHH N   1 ? 
ATOM   272  C CA  . LYS A 1 38  ? -30.515 -16.174 23.630  1.000 61.327  0 38  LYS HHH CA  1 ? 
ATOM   273  C C   . LYS A 1 38  ? -30.125 -17.233 22.596  1.000 59.374  0 38  LYS HHH C   1 ? 
ATOM   274  O O   . LYS A 1 38  ? -31.020 -17.914 22.086  1.000 59.149  0 38  LYS HHH O   1 ? 
ATOM   275  C CB  . LYS A 1 38  ? -30.865 -16.814 24.973  1.000 61.755  0 38  LYS HHH CB  1 ? 
ATOM   276  C CG  . LYS A 1 38  ? -29.868 -17.844 25.489  1.000 63.626  0 38  LYS HHH CG  1 ? 
ATOM   277  C CD  . LYS A 1 38  ? -30.445 -18.757 26.559  1.000 63.382  0 38  LYS HHH CD  1 ? 
ATOM   278  C CE  . LYS A 1 38  ? -29.404 -19.341 27.490  1.000 63.698  0 38  LYS HHH CE  1 ? 
ATOM   279  N NZ  . LYS A 1 38  ? -29.712 -19.028 28.906  1.000 64.952  0 38  LYS HHH NZ  1 ? 
ATOM   280  N N   . GLN A 1 39  ? -28.834 -17.376 22.309  1.000 60.991  0 39  GLN HHH N   1 ? 
ATOM   281  C CA  . GLN A 1 39  ? -28.335 -18.446 21.416  1.000 64.485  0 39  GLN HHH CA  1 ? 
ATOM   282  C C   . GLN A 1 39  ? -27.071 -19.093 21.990  1.000 67.792  0 39  GLN HHH C   1 ? 
ATOM   283  O O   . GLN A 1 39  ? -26.038 -18.402 22.081  1.000 59.677  0 39  GLN HHH O   1 ? 
ATOM   284  C CB  . GLN A 1 39  ? -28.072 -17.893 20.021  1.000 66.596  0 39  GLN HHH CB  1 ? 
ATOM   285  C CG  . GLN A 1 39  ? -27.872 -19.002 19.006  1.000 62.256  0 39  GLN HHH CG  1 ? 
ATOM   286  C CD  . GLN A 1 39  ? -27.627 -18.442 17.635  1.000 58.952  0 39  GLN HHH CD  1 ? 
ATOM   287  O OE1 . GLN A 1 39  ? -26.994 -17.396 17.464  1.000 58.674  0 39  GLN HHH OE1 1 ? 
ATOM   288  N NE2 . GLN A 1 39  ? -28.107 -19.170 16.649  1.000 60.152  0 39  GLN HHH NE2 1 ? 
ATOM   289  N N   . ARG A 1 40  ? -27.146 -20.396 22.275  1.000 75.500  0 40  ARG HHH N   1 ? 
ATOM   290  C CA  . ARG A 1 40  ? -25.996 -21.214 22.735  1.000 78.597  0 40  ARG HHH CA  1 ? 
ATOM   291  C C   . ARG A 1 40  ? -25.188 -21.643 21.506  1.000 82.984  0 40  ARG HHH C   1 ? 
ATOM   292  O O   . ARG A 1 40  ? -25.770 -21.687 20.407  1.000 82.511  0 40  ARG HHH O   1 ? 
ATOM   293  C CB  . ARG A 1 40  ? -26.485 -22.418 23.542  1.000 81.680  0 40  ARG HHH CB  1 ? 
ATOM   294  C CG  . ARG A 1 40  ? -27.601 -22.105 24.528  1.000 87.219  0 40  ARG HHH CG  1 ? 
ATOM   295  C CD  . ARG A 1 40  ? -27.504 -22.961 25.777  1.000 91.224  0 40  ARG HHH CD  1 ? 
ATOM   296  N NE  . ARG A 1 40  ? -26.282 -22.636 26.508  1.000 105.505 0 40  ARG HHH NE  1 ? 
ATOM   297  C CZ  . ARG A 1 40  ? -25.768 -23.348 27.507  1.000 95.819  0 40  ARG HHH CZ  1 ? 
ATOM   298  N NH1 . ARG A 1 40  ? -26.372 -24.446 27.932  1.000 93.637  0 40  ARG HHH NH1 1 ? 
ATOM   299  N NH2 . ARG A 1 40  ? -24.651 -22.948 28.088  1.000 92.666  0 40  ARG HHH NH2 1 ? 
ATOM   300  N N   . HIS A 1 41  ? -23.902 -21.949 21.697  1.000 92.547  0 41  HIS HHH N   1 ? 
ATOM   301  C CA  . HIS A 1 41  ? -22.949 -22.328 20.623  1.000 98.636  0 41  HIS HHH CA  1 ? 
ATOM   302  C C   . HIS A 1 41  ? -23.591 -23.387 19.722  1.000 104.536 0 41  HIS HHH C   1 ? 
ATOM   303  O O   . HIS A 1 41  ? -23.973 -24.456 20.254  1.000 106.414 0 41  HIS HHH O   1 ? 
ATOM   304  C CB  . HIS A 1 41  ? -21.614 -22.807 21.208  1.000 104.272 0 41  HIS HHH CB  1 ? 
ATOM   305  C CG  . HIS A 1 41  ? -20.460 -22.468 20.328  1.000 123.013 0 41  HIS HHH CG  1 ? 
ATOM   306  N ND1 . HIS A 1 41  ? -20.284 -21.191 19.818  1.000 127.657 0 41  HIS HHH ND1 1 ? 
ATOM   307  C CD2 . HIS A 1 41  ? -19.444 -23.218 19.846  1.000 132.395 0 41  HIS HHH CD2 1 ? 
ATOM   308  C CE1 . HIS A 1 41  ? -19.204 -21.167 19.065  1.000 132.793 0 41  HIS HHH CE1 1 ? 
ATOM   309  N NE2 . HIS A 1 41  ? -18.670 -22.399 19.066  1.000 141.695 0 41  HIS HHH NE2 1 ? 
ATOM   310  N N   . GLY A 1 42  ? -23.731 -23.070 18.427  1.000 105.804 0 42  GLY HHH N   1 ? 
ATOM   311  C CA  . GLY A 1 42  ? -24.184 -23.997 17.371  1.000 105.984 0 42  GLY HHH CA  1 ? 
ATOM   312  C C   . GLY A 1 42  ? -25.567 -24.565 17.648  1.000 111.647 0 42  GLY HHH C   1 ? 
ATOM   313  O O   . GLY A 1 42  ? -25.917 -25.562 16.991  1.000 123.452 0 42  GLY HHH O   1 ? 
ATOM   314  N N   . LYS A 1 43  ? -26.322 -23.972 18.586  1.000 106.836 0 43  LYS HHH N   1 ? 
ATOM   315  C CA  . LYS A 1 43  ? -27.745 -24.311 18.881  1.000 93.341  0 43  LYS HHH CA  1 ? 
ATOM   316  C C   . LYS A 1 43  ? -28.621 -23.242 18.207  1.000 83.285  0 43  LYS HHH C   1 ? 
ATOM   317  O O   . LYS A 1 43  ? -28.072 -22.490 17.368  1.000 72.058  0 43  LYS HHH O   1 ? 
ATOM   318  C CB  . LYS A 1 43  ? -27.968 -24.435 20.395  1.000 77.419  0 43  LYS HHH CB  1 ? 
ATOM   319  N N   . GLY A 1 44  ? -29.913 -23.174 18.555  1.000 77.114  0 44  GLY HHH N   1 ? 
ATOM   320  C CA  . GLY A 1 44  ? -30.906 -22.292 17.903  1.000 76.835  0 44  GLY HHH CA  1 ? 
ATOM   321  C C   . GLY A 1 44  ? -31.289 -21.069 18.734  1.000 76.005  0 44  GLY HHH C   1 ? 
ATOM   322  O O   . GLY A 1 44  ? -30.635 -20.818 19.778  1.000 82.893  0 44  GLY HHH O   1 ? 
ATOM   323  N N   . LEU A 1 45  ? -32.337 -20.353 18.304  1.000 65.126  0 45  LEU HHH N   1 ? 
ATOM   324  C CA  . LEU A 1 45  ? -32.751 -19.037 18.857  1.000 66.073  0 45  LEU HHH CA  1 ? 
ATOM   325  C C   . LEU A 1 45  ? -33.890 -19.216 19.868  1.000 65.049  0 45  LEU HHH C   1 ? 
ATOM   326  O O   . LEU A 1 45  ? -34.898 -19.845 19.511  1.000 62.468  0 45  LEU HHH O   1 ? 
ATOM   327  C CB  . LEU A 1 45  ? -33.173 -18.123 17.707  1.000 70.653  0 45  LEU HHH CB  1 ? 
ATOM   328  C CG  . LEU A 1 45  ? -32.023 -17.387 17.025  1.000 76.508  0 45  LEU HHH CG  1 ? 
ATOM   329  C CD1 . LEU A 1 45  ? -31.062 -18.376 16.413  1.000 90.172  0 45  LEU HHH CD1 1 ? 
ATOM   330  C CD2 . LEU A 1 45  ? -32.519 -16.435 15.956  1.000 77.623  0 45  LEU HHH CD2 1 ? 
ATOM   331  N N   . GLU A 1 46  ? -33.712 -18.665 21.076  1.000 60.049  0 46  GLU HHH N   1 ? 
ATOM   332  C CA  . GLU A 1 46  ? -34.684 -18.684 22.199  1.000 63.506  0 46  GLU HHH CA  1 ? 
ATOM   333  C C   . GLU A 1 46  ? -35.114 -17.244 22.506  1.000 68.059  0 46  GLU HHH C   1 ? 
ATOM   334  O O   . GLU A 1 46  ? -34.252 -16.398 22.809  1.000 69.310  0 46  GLU HHH O   1 ? 
ATOM   335  C CB  . GLU A 1 46  ? -34.052 -19.333 23.431  1.000 70.650  0 46  GLU HHH CB  1 ? 
ATOM   336  C CG  . GLU A 1 46  ? -35.072 -19.716 24.502  1.000 82.016  0 46  GLU HHH CG  1 ? 
ATOM   337  C CD  . GLU A 1 46  ? -34.627 -20.693 25.588  1.000 88.083  0 46  GLU HHH CD  1 ? 
ATOM   338  O OE1 . GLU A 1 46  ? -33.430 -20.693 25.958  1.000 99.120  0 46  GLU HHH OE1 1 ? 
ATOM   339  O OE2 . GLU A 1 46  ? -35.487 -21.450 26.072  1.000 86.371  0 46  GLU HHH OE2 1 ? 
ATOM   340  N N   . TRP A 1 47  ? -36.405 -16.951 22.412  1.000 70.047  0 47  TRP HHH N   1 ? 
ATOM   341  C CA  . TRP A 1 47  ? -36.924 -15.602 22.743  1.000 65.472  0 47  TRP HHH CA  1 ? 
ATOM   342  C C   . TRP A 1 47  ? -36.944 -15.455 24.264  1.000 65.646  0 47  TRP HHH C   1 ? 
ATOM   343  O O   . TRP A 1 47  ? -37.493 -16.349 24.952  1.000 71.912  0 47  TRP HHH O   1 ? 
ATOM   344  C CB  . TRP A 1 47  ? -38.309 -15.388 22.138  1.000 60.377  0 47  TRP HHH CB  1 ? 
ATOM   345  C CG  . TRP A 1 47  ? -38.847 -14.006 22.323  1.000 61.465  0 47  TRP HHH CG  1 ? 
ATOM   346  C CD1 . TRP A 1 47  ? -38.416 -12.854 21.729  1.000 66.243  0 47  TRP HHH CD1 1 ? 
ATOM   347  C CD2 . TRP A 1 47  ? -39.964 -13.633 23.147  1.000 65.927  0 47  TRP HHH CD2 1 ? 
ATOM   348  N NE1 . TRP A 1 47  ? -39.181 -11.787 22.135  1.000 64.359  0 47  TRP HHH NE1 1 ? 
ATOM   349  C CE2 . TRP A 1 47  ? -40.134 -12.237 23.009  1.000 64.880  0 47  TRP HHH CE2 1 ? 
ATOM   350  C CE3 . TRP A 1 47  ? -40.835 -14.342 23.981  1.000 67.825  0 47  TRP HHH CE3 1 ? 
ATOM   351  C CZ2 . TRP A 1 47  ? -41.144 -11.547 23.672  1.000 66.568  0 47  TRP HHH CZ2 1 ? 
ATOM   352  C CZ3 . TRP A 1 47  ? -41.829 -13.655 24.642  1.000 68.659  0 47  TRP HHH CZ3 1 ? 
ATOM   353  C CH2 . TRP A 1 47  ? -41.979 -12.277 24.489  1.000 69.173  0 47  TRP HHH CH2 1 ? 
ATOM   354  N N   . ILE A 1 48  ? -36.379 -14.361 24.759  1.000 62.926  0 48  ILE HHH N   1 ? 
ATOM   355  C CA  . ILE A 1 48  ? -36.380 -14.010 26.205  1.000 63.316  0 48  ILE HHH CA  1 ? 
ATOM   356  C C   . ILE A 1 48  ? -37.601 -13.124 26.501  1.000 64.313  0 48  ILE HHH C   1 ? 
ATOM   357  O O   . ILE A 1 48  ? -38.236 -13.320 27.552  1.000 57.664  0 48  ILE HHH O   1 ? 
ATOM   358  C CB  . ILE A 1 48  ? -35.053 -13.319 26.563  1.000 60.348  0 48  ILE HHH CB  1 ? 
ATOM   359  C CG1 . ILE A 1 48  ? -33.863 -14.209 26.218  1.000 59.322  0 48  ILE HHH CG1 1 ? 
ATOM   360  C CG2 . ILE A 1 48  ? -35.040 -12.899 28.017  1.000 62.629  0 48  ILE HHH CG2 1 ? 
ATOM   361  C CD1 . ILE A 1 48  ? -32.526 -13.544 26.400  1.000 59.773  0 48  ILE HHH CD1 1 ? 
ATOM   362  N N   . GLY A 1 49  ? -37.898 -12.157 25.635  1.000 61.110  0 49  GLY HHH N   1 ? 
ATOM   363  C CA  . GLY A 1 49  ? -38.898 -11.126 25.946  1.000 64.138  0 49  GLY HHH CA  1 ? 
ATOM   364  C C   . GLY A 1 49  ? -38.662 -9.830  25.202  1.000 65.951  0 49  GLY HHH C   1 ? 
ATOM   365  O O   . GLY A 1 49  ? -37.686 -9.718  24.434  1.000 61.999  0 49  GLY HHH O   1 ? 
ATOM   366  N N   . ASP A 1 50  ? -39.562 -8.883  25.422  1.000 69.245  0 50  ASP HHH N   1 ? 
ATOM   367  C CA  . ASP A 1 50  ? -39.559 -7.568  24.749  1.000 77.263  0 50  ASP HHH CA  1 ? 
ATOM   368  C C   . ASP A 1 50  ? -40.009 -6.516  25.751  1.000 73.810  0 50  ASP HHH C   1 ? 
ATOM   369  O O   . ASP A 1 50  ? -40.765 -6.843  26.690  1.000 65.594  0 50  ASP HHH O   1 ? 
ATOM   370  C CB  . ASP A 1 50  ? -40.457 -7.554  23.513  1.000 91.346  0 50  ASP HHH CB  1 ? 
ATOM   371  C CG  . ASP A 1 50  ? -41.945 -7.550  23.802  1.000 99.481  0 50  ASP HHH CG  1 ? 
ATOM   372  O OD1 . ASP A 1 50  ? -42.376 -8.427  24.573  1.000 109.076 0 50  ASP HHH OD1 1 ? 
ATOM   373  O OD2 . ASP A 1 50  ? -42.661 -6.681  23.246  1.000 99.617  0 50  ASP HHH OD2 1 ? 
ATOM   374  N N   . ILE A 1 51  ? -39.549 -5.294  25.529  1.000 79.223  0 51  ILE HHH N   1 ? 
ATOM   375  C CA  . ILE A 1 51  ? -39.900 -4.113  26.357  1.000 85.435  0 51  ILE HHH CA  1 ? 
ATOM   376  C C   . ILE A 1 51  ? -40.347 -3.019  25.390  1.000 87.169  0 51  ILE HHH C   1 ? 
ATOM   377  O O   . ILE A 1 51  ? -39.645 -2.789  24.393  1.000 89.278  0 51  ILE HHH O   1 ? 
ATOM   378  C CB  . ILE A 1 51  ? -38.719 -3.691  27.250  1.000 84.426  0 51  ILE HHH CB  1 ? 
ATOM   379  C CG1 . ILE A 1 51  ? -38.981 -2.344  27.921  1.000 93.472  0 51  ILE HHH CG1 1 ? 
ATOM   380  C CG2 . ILE A 1 51  ? -37.418 -3.681  26.468  1.000 87.936  0 51  ILE HHH CG2 1 ? 
ATOM   381  C CD1 . ILE A 1 51  ? -37.969 -1.971  28.976  1.000 97.732  0 51  ILE HHH CD1 1 ? 
ATOM   382  N N   . ASN A 1 52  ? -41.493 -2.400  25.659  1.000 91.426  0 52  ASN HHH N   1 ? 
ATOM   383  C CA  . ASN A 1 52  ? -41.930 -1.187  24.930  1.000 90.309  0 52  ASN HHH CA  1 ? 
ATOM   384  C C   . ASN A 1 52  ? -41.245 0.015   25.574  1.000 92.715  0 52  ASN HHH C   1 ? 
ATOM   385  O O   . ASN A 1 52  ? -41.540 0.365   26.716  1.000 92.290  0 52  ASN HHH O   1 ? 
ATOM   386  C CB  . ASN A 1 52  ? -43.449 -1.055  24.898  1.000 92.777  0 52  ASN HHH CB  1 ? 
ATOM   387  C CG  . ASN A 1 52  ? -43.890 0.188   24.161  1.000 95.497  0 52  ASN HHH CG  1 ? 
ATOM   388  O OD1 . ASN A 1 52  ? -43.267 0.579   23.174  1.000 96.961  0 52  ASN HHH OD1 1 ? 
ATOM   389  N ND2 . ASN A 1 52  ? -44.956 0.812   24.635  1.000 104.459 0 52  ASN HHH ND2 1 ? 
ATOM   390  N N   . PRO A 1 53  ? -40.307 0.680   24.864  1.000 93.145  0 53  PRO HHH N   1 ? 
ATOM   391  C CA  . PRO A 1 53  ? -39.535 1.782   25.437  1.000 101.103 0 53  PRO HHH CA  1 ? 
ATOM   392  C C   . PRO A 1 53  ? -40.392 2.949   25.950  1.000 100.670 0 53  PRO HHH C   1 ? 
ATOM   393  O O   . PRO A 1 53  ? -39.951 3.632   26.848  1.000 91.480  0 53  PRO HHH O   1 ? 
ATOM   394  C CB  . PRO A 1 53  ? -38.671 2.264   24.262  1.000 108.696 0 53  PRO HHH CB  1 ? 
ATOM   395  C CG  . PRO A 1 53  ? -39.407 1.773   23.037  1.000 106.194 0 53  PRO HHH CG  1 ? 
ATOM   396  C CD  . PRO A 1 53  ? -39.964 0.435   23.458  1.000 97.670  0 53  PRO HHH CD  1 ? 
ATOM   397  N N   . ASN A 1 54  ? -41.582 3.141   25.374  1.000 102.570 0 54  ASN HHH N   1 ? 
ATOM   398  C CA  . ASN A 1 54  ? -42.532 4.211   25.778  1.000 108.560 0 54  ASN HHH CA  1 ? 
ATOM   399  C C   . ASN A 1 54  ? -42.892 4.068   27.262  1.000 101.845 0 54  ASN HHH C   1 ? 
ATOM   400  O O   . ASN A 1 54  ? -42.595 5.013   28.017  1.000 107.817 0 54  ASN HHH O   1 ? 
ATOM   401  C CB  . ASN A 1 54  ? -43.787 4.244   24.902  1.000 109.961 0 54  ASN HHH CB  1 ? 
ATOM   402  C CG  . ASN A 1 54  ? -43.740 5.345   23.868  1.000 118.644 0 54  ASN HHH CG  1 ? 
ATOM   403  O OD1 . ASN A 1 54  ? -43.275 6.446   24.161  1.000 120.918 0 54  ASN HHH OD1 1 ? 
ATOM   404  N ND2 . ASN A 1 54  ? -44.211 5.056   22.664  1.000 121.049 0 54  ASN HHH ND2 1 ? 
ATOM   405  N N   . ASN A 1 55  ? -43.507 2.950   27.663  1.000 94.255  0 55  ASN HHH N   1 ? 
ATOM   406  C CA  . ASN A 1 55  ? -44.052 2.764   29.040  1.000 95.110  0 55  ASN HHH CA  1 ? 
ATOM   407  C C   . ASN A 1 55  ? -43.084 1.931   29.890  1.000 93.806  0 55  ASN HHH C   1 ? 
ATOM   408  O O   . ASN A 1 55  ? -43.256 1.904   31.129  1.000 88.522  0 55  ASN HHH O   1 ? 
ATOM   409  C CB  . ASN A 1 55  ? -45.459 2.158   29.042  1.000 94.551  0 55  ASN HHH CB  1 ? 
ATOM   410  C CG  . ASN A 1 55  ? -45.629 1.006   28.073  1.000 108.066 0 55  ASN HHH CG  1 ? 
ATOM   411  O OD1 . ASN A 1 55  ? -44.696 0.252   27.810  1.000 126.409 0 55  ASN HHH OD1 1 ? 
ATOM   412  N ND2 . ASN A 1 55  ? -46.821 0.854   27.528  1.000 116.034 0 55  ASN HHH ND2 1 ? 
ATOM   413  N N   . GLY A 1 56  ? -42.103 1.285   29.251  1.000 103.224 0 56  GLY HHH N   1 ? 
ATOM   414  C CA  . GLY A 1 56  ? -41.186 0.323   29.893  1.000 98.148  0 56  GLY HHH CA  1 ? 
ATOM   415  C C   . GLY A 1 56  ? -41.874 -1.000  30.187  1.000 82.911  0 56  GLY HHH C   1 ? 
ATOM   416  O O   . GLY A 1 56  ? -41.314 -1.773  30.963  1.000 75.451  0 56  GLY HHH O   1 ? 
ATOM   417  N N   . GLY A 1 57  ? -43.060 -1.228  29.614  1.000 76.314  0 57  GLY HHH N   1 ? 
ATOM   418  C CA  . GLY A 1 57  ? -43.832 -2.472  29.757  1.000 82.324  0 57  GLY HHH CA  1 ? 
ATOM   419  C C   . GLY A 1 57  ? -43.051 -3.628  29.163  1.000 86.877  0 57  GLY HHH C   1 ? 
ATOM   420  O O   . GLY A 1 57  ? -42.362 -3.431  28.142  1.000 85.555  0 57  GLY HHH O   1 ? 
ATOM   421  N N   . THR A 1 58  ? -43.102 -4.784  29.809  1.000 78.509  0 58  THR HHH N   1 ? 
ATOM   422  C CA  . THR A 1 58  ? -42.246 -5.941  29.477  1.000 79.021  0 58  THR HHH CA  1 ? 
ATOM   423  C C   . THR A 1 58  ? -43.105 -7.200  29.425  1.000 80.551  0 58  THR HHH C   1 ? 
ATOM   424  O O   . THR A 1 58  ? -43.915 -7.400  30.339  1.000 86.469  0 58  THR HHH O   1 ? 
ATOM   425  C CB  . THR A 1 58  ? -41.124 -6.071  30.509  1.000 79.830  0 58  THR HHH CB  1 ? 
ATOM   426  O OG1 . THR A 1 58  ? -41.748 -6.069  31.790  1.000 85.404  0 58  THR HHH OG1 1 ? 
ATOM   427  C CG2 . THR A 1 58  ? -40.113 -4.948  30.438  1.000 80.532  0 58  THR HHH CG2 1 ? 
ATOM   428  N N   . ILE A 1 59  ? -42.935 -8.005  28.383  1.000 82.613  0 59  ILE HHH N   1 ? 
ATOM   429  C CA  . ILE A 1 59  ? -43.394 -9.422  28.355  1.000 82.800  0 59  ILE HHH CA  1 ? 
ATOM   430  C C   . ILE A 1 59  ? -42.146 -10.308 28.379  1.000 74.992  0 59  ILE HHH C   1 ? 
ATOM   431  O O   . ILE A 1 59  ? -41.162 -9.987  27.675  1.000 66.233  0 59  ILE HHH O   1 ? 
ATOM   432  C CB  . ILE A 1 59  ? -44.293 -9.699  27.139  1.000 91.319  0 59  ILE HHH CB  1 ? 
ATOM   433  C CG1 . ILE A 1 59  ? -45.541 -8.808  27.142  1.000 108.927 0 59  ILE HHH CG1 1 ? 
ATOM   434  C CG2 . ILE A 1 59  ? -44.653 -11.170 27.063  1.000 86.188  0 59  ILE HHH CG2 1 ? 
ATOM   435  C CD1 . ILE A 1 59  ? -45.498 -7.650  26.151  1.000 121.474 0 59  ILE HHH CD1 1 ? 
ATOM   436  N N   . TYR A 1 60  ? -42.186 -11.362 29.193  1.000 69.617  0 60  TYR HHH N   1 ? 
ATOM   437  C CA  . TYR A 1 60  ? -41.085 -12.342 29.373  1.000 71.395  0 60  TYR HHH CA  1 ? 
ATOM   438  C C   . TYR A 1 60  ? -41.588 -13.718 28.928  1.000 69.829  0 60  TYR HHH C   1 ? 
ATOM   439  O O   . TYR A 1 60  ? -42.764 -14.024 29.143  1.000 78.671  0 60  TYR HHH O   1 ? 
ATOM   440  C CB  . TYR A 1 60  ? -40.596 -12.354 30.831  1.000 69.224  0 60  TYR HHH CB  1 ? 
ATOM   441  C CG  . TYR A 1 60  ? -39.931 -11.082 31.310  1.000 71.020  0 60  TYR HHH CG  1 ? 
ATOM   442  C CD1 . TYR A 1 60  ? -38.592 -10.819 31.041  1.000 74.545  0 60  TYR HHH CD1 1 ? 
ATOM   443  C CD2 . TYR A 1 60  ? -40.629 -10.133 32.045  1.000 73.912  0 60  TYR HHH CD2 1 ? 
ATOM   444  C CE1 . TYR A 1 60  ? -37.977 -9.643  31.453  1.000 72.079  0 60  TYR HHH CE1 1 ? 
ATOM   445  C CE2 . TYR A 1 60  ? -40.029 -8.957  32.476  1.000 72.393  0 60  TYR HHH CE2 1 ? 
ATOM   446  C CZ  . TYR A 1 60  ? -38.699 -8.712  32.180  1.000 72.781  0 60  TYR HHH CZ  1 ? 
ATOM   447  O OH  . TYR A 1 60  ? -38.112 -7.550  32.579  1.000 72.836  0 60  TYR HHH OH  1 ? 
ATOM   448  N N   . SER A 1 61  ? -40.721 -14.541 28.340  1.000 74.823  0 61  SER HHH N   1 ? 
ATOM   449  C CA  . SER A 1 61  ? -40.947 -16.008 28.227  1.000 75.627  0 61  SER HHH CA  1 ? 
ATOM   450  C C   . SER A 1 61  ? -40.927 -16.592 29.640  1.000 73.573  0 61  SER HHH C   1 ? 
ATOM   451  O O   . SER A 1 61  ? -40.116 -16.124 30.449  1.000 70.831  0 61  SER HHH O   1 ? 
ATOM   452  C CB  . SER A 1 61  ? -39.930 -16.683 27.348  1.000 70.846  0 61  SER HHH CB  1 ? 
ATOM   453  O OG  . SER A 1 61  ? -39.780 -18.035 27.728  1.000 77.290  0 61  SER HHH OG  1 ? 
ATOM   454  N N   . GLN A 1 62  ? -41.776 -17.582 29.915  1.000 80.698  0 62  GLN HHH N   1 ? 
ATOM   455  C CA  . GLN A 1 62  ? -41.818 -18.286 31.227  1.000 81.345  0 62  GLN HHH CA  1 ? 
ATOM   456  C C   . GLN A 1 62  ? -40.400 -18.688 31.650  1.000 68.808  0 62  GLN HHH C   1 ? 
ATOM   457  O O   . GLN A 1 62  ? -40.013 -18.320 32.761  1.000 63.086  0 62  GLN HHH O   1 ? 
ATOM   458  C CB  . GLN A 1 62  ? -42.723 -19.526 31.187  1.000 92.339  0 62  GLN HHH CB  1 ? 
ATOM   459  C CG  . GLN A 1 62  ? -43.084 -20.074 32.567  1.000 92.414  0 62  GLN HHH CG  1 ? 
ATOM   460  C CD  . GLN A 1 62  ? -43.891 -19.079 33.369  1.000 94.531  0 62  GLN HHH CD  1 ? 
ATOM   461  O OE1 . GLN A 1 62  ? -44.779 -18.406 32.841  1.000 88.872  0 62  GLN HHH OE1 1 ? 
ATOM   462  N NE2 . GLN A 1 62  ? -43.575 -18.960 34.653  1.000 92.665  0 62  GLN HHH NE2 1 ? 
ATOM   463  N N   . LYS A 1 63  ? -39.660 -19.398 30.792  1.000 64.945  0 63  LYS HHH N   1 ? 
ATOM   464  C CA  . LYS A 1 63  ? -38.345 -20.005 31.140  1.000 62.199  0 63  LYS HHH CA  1 ? 
ATOM   465  C C   . LYS A 1 63  ? -37.422 -18.932 31.733  1.000 59.604  0 63  LYS HHH C   1 ? 
ATOM   466  O O   . LYS A 1 63  ? -36.452 -19.318 32.377  1.000 59.421  0 63  LYS HHH O   1 ? 
ATOM   467  C CB  . LYS A 1 63  ? -37.717 -20.706 29.924  1.000 57.285  0 63  LYS HHH CB  1 ? 
ATOM   468  N N   . PHE A 1 64  ? -37.691 -17.640 31.517  1.000 62.996  0 64  PHE HHH N   1 ? 
ATOM   469  C CA  . PHE A 1 64  ? -36.760 -16.542 31.897  1.000 65.615  0 64  PHE HHH CA  1 ? 
ATOM   470  C C   . PHE A 1 64  ? -37.342 -15.610 32.954  1.000 70.861  0 64  PHE HHH C   1 ? 
ATOM   471  O O   . PHE A 1 64  ? -36.562 -14.795 33.455  1.000 80.640  0 64  PHE HHH O   1 ? 
ATOM   472  C CB  . PHE A 1 64  ? -36.366 -15.682 30.699  1.000 64.707  0 64  PHE HHH CB  1 ? 
ATOM   473  C CG  . PHE A 1 64  ? -35.490 -16.384 29.700  1.000 59.483  0 64  PHE HHH CG  1 ? 
ATOM   474  C CD1 . PHE A 1 64  ? -36.053 -17.129 28.678  1.000 54.892  0 64  PHE HHH CD1 1 ? 
ATOM   475  C CD2 . PHE A 1 64  ? -34.107 -16.296 29.784  1.000 61.367  0 64  PHE HHH CD2 1 ? 
ATOM   476  C CE1 . PHE A 1 64  ? -35.251 -17.768 27.752  1.000 54.986  0 64  PHE HHH CE1 1 ? 
ATOM   477  C CE2 . PHE A 1 64  ? -33.304 -16.933 28.849  1.000 60.947  0 64  PHE HHH CE2 1 ? 
ATOM   478  C CZ  . PHE A 1 64  ? -33.881 -17.664 27.835  1.000 58.272  0 64  PHE HHH CZ  1 ? 
ATOM   479  N N   . LYS A 1 65  ? -38.636 -15.687 33.265  1.000 80.942  0 65  LYS HHH N   1 ? 
ATOM   480  C CA  . LYS A 1 65  ? -39.214 -14.953 34.423  1.000 76.631  0 65  LYS HHH CA  1 ? 
ATOM   481  C C   . LYS A 1 65  ? -38.289 -15.244 35.612  1.000 77.412  0 65  LYS HHH C   1 ? 
ATOM   482  O O   . LYS A 1 65  ? -37.985 -16.440 35.841  1.000 83.334  0 65  LYS HHH O   1 ? 
ATOM   483  C CB  . LYS A 1 65  ? -40.677 -15.359 34.640  1.000 73.735  0 65  LYS HHH CB  1 ? 
ATOM   484  N N   . GLY A 1 66  ? -37.754 -14.198 36.249  1.000 74.909  0 66  GLY HHH N   1 ? 
ATOM   485  C CA  . GLY A 1 66  ? -36.890 -14.323 37.439  1.000 80.275  0 66  GLY HHH CA  1 ? 
ATOM   486  C C   . GLY A 1 66  ? -35.419 -14.549 37.112  1.000 80.309  0 66  GLY HHH C   1 ? 
ATOM   487  O O   . GLY A 1 66  ? -34.593 -14.532 38.055  1.000 88.262  0 66  GLY HHH O   1 ? 
ATOM   488  N N   . LYS A 1 67  ? -35.077 -14.772 35.844  1.000 73.667  0 67  LYS HHH N   1 ? 
ATOM   489  C CA  . LYS A 1 67  ? -33.664 -14.812 35.387  1.000 73.493  0 67  LYS HHH CA  1 ? 
ATOM   490  C C   . LYS A 1 67  ? -33.298 -13.441 34.802  1.000 65.296  0 67  LYS HHH C   1 ? 
ATOM   491  O O   . LYS A 1 67  ? -32.280 -12.854 35.190  1.000 63.290  0 67  LYS HHH O   1 ? 
ATOM   492  C CB  . LYS A 1 67  ? -33.477 -15.944 34.375  1.000 69.554  0 67  LYS HHH CB  1 ? 
ATOM   493  C CG  . LYS A 1 67  ? -32.186 -15.914 33.570  1.000 68.409  0 67  LYS HHH CG  1 ? 
ATOM   494  C CD  . LYS A 1 67  ? -30.959 -16.299 34.350  1.000 74.583  0 67  LYS HHH CD  1 ? 
ATOM   495  C CE  . LYS A 1 67  ? -31.092 -17.627 35.059  1.000 84.901  0 67  LYS HHH CE  1 ? 
ATOM   496  N NZ  . LYS A 1 67  ? -30.037 -17.794 36.085  1.000 93.036  0 67  LYS HHH NZ  1 ? 
ATOM   497  N N   . ALA A 1 68  ? -34.101 -12.952 33.877  1.000 60.675  0 68  ALA HHH N   1 ? 
ATOM   498  C CA  . ALA A 1 68  ? -33.765 -11.755 33.087  1.000 70.071  0 68  ALA HHH CA  1 ? 
ATOM   499  C C   . ALA A 1 68  ? -34.602 -10.575 33.556  1.000 73.316  0 68  ALA HHH C   1 ? 
ATOM   500  O O   . ALA A 1 68  ? -35.730 -10.761 34.036  1.000 88.491  0 68  ALA HHH O   1 ? 
ATOM   501  C CB  . ALA A 1 68  ? -33.997 -12.040 31.639  1.000 70.247  0 68  ALA HHH CB  1 ? 
ATOM   502  N N   . THR A 1 69  ? -34.065 -9.384  33.391  1.000 74.579  0 69  THR HHH N   1 ? 
ATOM   503  C CA  . THR A 1 69  ? -34.795 -8.143  33.717  1.000 80.199  0 69  THR HHH CA  1 ? 
ATOM   504  C C   . THR A 1 69  ? -34.531 -7.150  32.592  1.000 70.680  0 69  THR HHH C   1 ? 
ATOM   505  O O   . THR A 1 69  ? -33.390 -6.706  32.417  1.000 72.599  0 69  THR HHH O   1 ? 
ATOM   506  C CB  . THR A 1 69  ? -34.430 -7.621  35.108  1.000 83.266  0 69  THR HHH CB  1 ? 
ATOM   507  O OG1 . THR A 1 69  ? -35.300 -6.532  35.387  1.000 82.103  0 69  THR HHH OG1 1 ? 
ATOM   508  C CG2 . THR A 1 69  ? -33.013 -7.117  35.194  1.000 98.035  0 69  THR HHH CG2 1 ? 
ATOM   509  N N   . LEU A 1 70  ? -35.561 -6.844  31.828  1.000 68.537  0 70  LEU HHH N   1 ? 
ATOM   510  C CA  . LEU A 1 70  ? -35.419 -5.940  30.667  1.000 74.635  0 70  LEU HHH CA  1 ? 
ATOM   511  C C   . LEU A 1 70  ? -35.669 -4.511  31.144  1.000 80.904  0 70  LEU HHH C   1 ? 
ATOM   512  O O   . LEU A 1 70  ? -36.705 -4.241  31.772  1.000 75.032  0 70  LEU HHH O   1 ? 
ATOM   513  C CB  . LEU A 1 70  ? -36.397 -6.357  29.573  1.000 74.560  0 70  LEU HHH CB  1 ? 
ATOM   514  C CG  . LEU A 1 70  ? -35.832 -7.248  28.467  1.000 74.110  0 70  LEU HHH CG  1 ? 
ATOM   515  C CD1 . LEU A 1 70  ? -35.275 -8.562  28.988  1.000 74.383  0 70  LEU HHH CD1 1 ? 
ATOM   516  C CD2 . LEU A 1 70  ? -36.916 -7.536  27.460  1.000 80.469  0 70  LEU HHH CD2 1 ? 
ATOM   517  N N   . THR A 1 71  ? -34.736 -3.621  30.850  1.000 89.200  0 71  THR HHH N   1 ? 
ATOM   518  C CA  . THR A 1 71  ? -34.786 -2.212  31.287  1.000 91.924  0 71  THR HHH CA  1 ? 
ATOM   519  C C   . THR A 1 71  ? -34.558 -1.337  30.066  1.000 87.528  0 71  THR HHH C   1 ? 
ATOM   520  O O   . THR A 1 71  ? -34.278 -1.873  28.994  1.000 95.502  0 71  THR HHH O   1 ? 
ATOM   521  C CB  . THR A 1 71  ? -33.727 -1.970  32.365  1.000 109.984 0 71  THR HHH CB  1 ? 
ATOM   522  O OG1 . THR A 1 71  ? -34.055 -2.819  33.465  1.000 118.289 0 71  THR HHH OG1 1 ? 
ATOM   523  C CG2 . THR A 1 71  ? -33.614 -0.522  32.796  1.000 114.498 0 71  THR HHH CG2 1 ? 
ATOM   524  N N   . VAL A 1 72  ? -34.649 -0.028  30.241  1.000 97.666  0 72  VAL HHH N   1 ? 
ATOM   525  C CA  . VAL A 1 72  ? -34.416 0.929   29.134  1.000 103.551 0 72  VAL HHH CA  1 ? 
ATOM   526  C C   . VAL A 1 72  ? -33.958 2.280   29.695  1.000 101.431 0 72  VAL HHH C   1 ? 
ATOM   527  O O   . VAL A 1 72  ? -33.975 2.469   30.922  1.000 109.347 0 72  VAL HHH O   1 ? 
ATOM   528  C CB  . VAL A 1 72  ? -35.712 1.013   28.308  1.000 108.606 0 72  VAL HHH CB  1 ? 
ATOM   529  C CG1 . VAL A 1 72  ? -36.634 2.123   28.786  1.000 112.200 0 72  VAL HHH CG1 1 ? 
ATOM   530  C CG2 . VAL A 1 72  ? -35.416 1.133   26.828  1.000 107.555 0 72  VAL HHH CG2 1 ? 
ATOM   531  N N   . ASP A 1 73  ? -33.531 3.179   28.814  1.000 103.999 0 73  ASP HHH N   1 ? 
ATOM   532  C CA  . ASP A 1 73  ? -33.230 4.596   29.148  1.000 108.353 0 73  ASP HHH CA  1 ? 
ATOM   533  C C   . ASP A 1 73  ? -33.653 5.453   27.949  1.000 112.842 0 73  ASP HHH C   1 ? 
ATOM   534  O O   . ASP A 1 73  ? -32.866 5.553   26.982  1.000 113.794 0 73  ASP HHH O   1 ? 
ATOM   535  C CB  . ASP A 1 73  ? -31.761 4.767   29.545  1.000 95.625  0 73  ASP HHH CB  1 ? 
ATOM   536  N N   . LYS A 1 74  ? -34.874 5.999   27.987  1.000 113.235 0 74  LYS HHH N   1 ? 
ATOM   537  C CA  . LYS A 1 74  ? -35.450 6.832   26.896  1.000 117.085 0 74  LYS HHH CA  1 ? 
ATOM   538  C C   . LYS A 1 74  ? -34.460 7.965   26.587  1.000 124.887 0 74  LYS HHH C   1 ? 
ATOM   539  O O   . LYS A 1 74  ? -34.144 8.176   25.387  1.000 113.832 0 74  LYS HHH O   1 ? 
ATOM   540  C CB  . LYS A 1 74  ? -36.835 7.357   27.295  1.000 107.462 0 74  LYS HHH CB  1 ? 
ATOM   541  N N   . SER A 1 75  ? -33.968 8.629   27.642  1.000 135.329 0 75  SER HHH N   1 ? 
ATOM   542  C CA  . SER A 1 75  ? -33.003 9.761   27.593  1.000 134.738 0 75  SER HHH CA  1 ? 
ATOM   543  C C   . SER A 1 75  ? -31.773 9.376   26.762  1.000 137.707 0 75  SER HHH C   1 ? 
ATOM   544  O O   . SER A 1 75  ? -31.365 10.192  25.919  1.000 152.770 0 75  SER HHH O   1 ? 
ATOM   545  C CB  . SER A 1 75  ? -32.607 10.214  28.982  1.000 126.153 0 75  SER HHH CB  1 ? 
ATOM   546  O OG  . SER A 1 75  ? -31.865 9.210   29.659  1.000 120.140 0 75  SER HHH OG  1 ? 
ATOM   547  N N   . SER A 1 76  ? -31.223 8.177   26.981  1.000 133.401 0 76  SER HHH N   1 ? 
ATOM   548  C CA  . SER A 1 76  ? -29.972 7.683   26.343  1.000 123.062 0 76  SER HHH CA  1 ? 
ATOM   549  C C   . SER A 1 76  ? -30.277 6.782   25.135  1.000 119.297 0 76  SER HHH C   1 ? 
ATOM   550  O O   . SER A 1 76  ? -29.316 6.232   24.578  1.000 122.777 0 76  SER HHH O   1 ? 
ATOM   551  C CB  . SER A 1 76  ? -29.095 6.973   27.352  1.000 119.930 0 76  SER HHH CB  1 ? 
ATOM   552  O OG  . SER A 1 76  ? -29.376 5.580   27.400  1.000 109.732 0 76  SER HHH OG  1 ? 
ATOM   553  N N   . SER A 1 77  ? -31.542 6.629   24.728  1.000 114.373 0 77  SER HHH N   1 ? 
ATOM   554  C CA  . SER A 1 77  ? -31.947 5.742   23.602  1.000 109.438 0 77  SER HHH CA  1 ? 
ATOM   555  C C   . SER A 1 77  ? -31.143 4.431   23.664  1.000 104.901 0 77  SER HHH C   1 ? 
ATOM   556  O O   . SER A 1 77  ? -30.374 4.155   22.727  1.000 107.849 0 77  SER HHH O   1 ? 
ATOM   557  C CB  . SER A 1 77  ? -31.779 6.440   22.268  1.000 110.999 0 77  SER HHH CB  1 ? 
ATOM   558  O OG  . SER A 1 77  ? -30.409 6.703   21.990  1.000 112.289 0 77  SER HHH OG  1 ? 
ATOM   559  N N   . THR A 1 78  ? -31.311 3.661   24.743  1.000 93.479  0 78  THR HHH N   1 ? 
ATOM   560  C CA  . THR A 1 78  ? -30.554 2.415   25.028  1.000 89.601  0 78  THR HHH CA  1 ? 
ATOM   561  C C   . THR A 1 78  ? -31.417 1.432   25.826  1.000 95.160  0 78  THR HHH C   1 ? 
ATOM   562  O O   . THR A 1 78  ? -31.936 1.844   26.882  1.000 105.742 0 78  THR HHH O   1 ? 
ATOM   563  C CB  . THR A 1 78  ? -29.282 2.718   25.827  1.000 90.180  0 78  THR HHH CB  1 ? 
ATOM   564  O OG1 . THR A 1 78  ? -28.449 3.563   25.035  1.000 102.425 0 78  THR HHH OG1 1 ? 
ATOM   565  C CG2 . THR A 1 78  ? -28.506 1.478   26.201  1.000 86.743  0 78  THR HHH CG2 1 ? 
ATOM   566  N N   . ALA A 1 79  ? -31.527 0.181   25.358  1.000 87.770  0 79  ALA HHH N   1 ? 
ATOM   567  C CA  . ALA A 1 79  ? -32.211 -0.934  26.059  1.000 74.228  0 79  ALA HHH CA  1 ? 
ATOM   568  C C   . ALA A 1 79  ? -31.192 -1.651  26.940  1.000 69.136  0 79  ALA HHH C   1 ? 
ATOM   569  O O   . ALA A 1 79  ? -29.984 -1.414  26.775  1.000 68.955  0 79  ALA HHH O   1 ? 
ATOM   570  C CB  . ALA A 1 79  ? -32.837 -1.894  25.076  1.000 74.862  0 79  ALA HHH CB  1 ? 
ATOM   571  N N   . PHE A 1 80  ? -31.669 -2.513  27.833  1.000 67.512  0 80  PHE HHH N   1 ? 
ATOM   572  C CA  . PHE A 1 80  ? -30.827 -3.217  28.829  1.000 68.116  0 80  PHE HHH CA  1 ? 
ATOM   573  C C   . PHE A 1 80  ? -31.449 -4.560  29.189  1.000 64.281  0 80  PHE HHH C   1 ? 
ATOM   574  O O   . PHE A 1 80  ? -32.686 -4.661  29.285  1.000 66.663  0 80  PHE HHH O   1 ? 
ATOM   575  C CB  . PHE A 1 80  ? -30.680 -2.383  30.100  1.000 72.209  0 80  PHE HHH CB  1 ? 
ATOM   576  C CG  . PHE A 1 80  ? -29.826 -1.150  29.965  1.000 73.862  0 80  PHE HHH CG  1 ? 
ATOM   577  C CD1 . PHE A 1 80  ? -28.451 -1.251  29.861  1.000 75.198  0 80  PHE HHH CD1 1 ? 
ATOM   578  C CD2 . PHE A 1 80  ? -30.393 0.114   29.976  1.000 80.576  0 80  PHE HHH CD2 1 ? 
ATOM   579  C CE1 . PHE A 1 80  ? -27.662 -0.117  29.745  1.000 81.022  0 80  PHE HHH CE1 1 ? 
ATOM   580  C CE2 . PHE A 1 80  ? -29.603 1.249   29.867  1.000 84.050  0 80  PHE HHH CE2 1 ? 
ATOM   581  C CZ  . PHE A 1 80  ? -28.237 1.131   29.751  1.000 80.684  0 80  PHE HHH CZ  1 ? 
ATOM   582  N N   . MET A 1 81  ? -30.601 -5.553  29.424  1.000 63.948  0 81  MET HHH N   1 ? 
ATOM   583  C CA  . MET A 1 81  ? -31.049 -6.867  29.933  1.000 71.048  0 81  MET HHH CA  1 ? 
ATOM   584  C C   . MET A 1 81  ? -30.134 -7.321  31.071  1.000 70.987  0 81  MET HHH C   1 ? 
ATOM   585  O O   . MET A 1 81  ? -28.936 -7.496  30.808  1.000 78.801  0 81  MET HHH O   1 ? 
ATOM   586  C CB  . MET A 1 81  ? -31.030 -7.906  28.817  1.000 73.521  0 81  MET HHH CB  1 ? 
ATOM   587  C CG  . MET A 1 81  ? -31.671 -9.192  29.246  1.000 80.312  0 81  MET HHH CG  1 ? 
ATOM   588  S SD  . MET A 1 81  ? -31.710 -10.371 27.907  1.000 96.616  0 81  MET HHH SD  1 ? 
ATOM   589  C CE  . MET A 1 81  ? -29.959 -10.491 27.556  1.000 98.022  0 81  MET HHH CE  1 ? 
ATOM   590  N N   . GLU A 1 82  ? -30.691 -7.540  32.267  1.000 68.923  0 82  GLU HHH N   1 ? 
ATOM   591  C CA  . GLU A 1 82  ? -29.918 -7.952  33.471  1.000 75.956  0 82  GLU HHH CA  1 ? 
ATOM   592  C C   . GLU A 1 82  ? -30.225 -9.430  33.795  1.000 68.467  0 82  GLU HHH C   1 ? 
ATOM   593  O O   . GLU A 1 82  ? -31.351 -9.757  34.251  1.000 62.092  0 82  GLU HHH O   1 ? 
ATOM   594  C CB  . GLU A 1 82  ? -30.148 -6.942  34.607  1.000 91.303  0 82  GLU HHH CB  1 ? 
ATOM   595  C CG  . GLU A 1 82  ? -29.651 -7.394  35.978  1.000 103.855 0 82  GLU HHH CG  1 ? 
ATOM   596  C CD  . GLU A 1 82  ? -30.368 -6.762  37.165  1.000 112.919 0 82  GLU HHH CD  1 ? 
ATOM   597  O OE1 . GLU A 1 82  ? -30.455 -5.512  37.203  1.000 110.718 0 82  GLU HHH OE1 1 ? 
ATOM   598  O OE2 . GLU A 1 82  ? -30.873 -7.523  38.036  1.000 116.286 0 82  GLU HHH OE2 1 ? 
ATOM   599  N N   . LEU A 1 83  ? -29.241 -10.303 33.570  1.000 63.371  0 83  LEU HHH N   1 ? 
ATOM   600  C CA  . LEU A 1 83  ? -29.317 -11.744 33.928  1.000 63.407  0 83  LEU HHH CA  1 ? 
ATOM   601  C C   . LEU A 1 83  ? -28.697 -11.968 35.306  1.000 65.429  0 83  LEU HHH C   1 ? 
ATOM   602  O O   . LEU A 1 83  ? -27.552 -11.541 35.483  1.000 64.707  0 83  LEU HHH O   1 ? 
ATOM   603  C CB  . LEU A 1 83  ? -28.556 -12.557 32.889  1.000 66.524  0 83  LEU HHH CB  1 ? 
ATOM   604  C CG  . LEU A 1 83  ? -29.371 -12.990 31.682  1.000 73.760  0 83  LEU HHH CG  1 ? 
ATOM   605  C CD1 . LEU A 1 83  ? -29.945 -11.795 30.937  1.000 82.967  0 83  LEU HHH CD1 1 ? 
ATOM   606  C CD2 . LEU A 1 83  ? -28.495 -13.805 30.762  1.000 82.029  0 83  LEU HHH CD2 1 ? 
ATOM   607  N N   . ARG A 1 84  ? -29.394 -12.678 36.199  1.000 68.941  0 84  ARG HHH N   1 ? 
ATOM   608  C CA  . ARG A 1 84  ? -28.982 -12.901 37.609  1.000 73.840  0 84  ARG HHH CA  1 ? 
ATOM   609  C C   . ARG A 1 84  ? -28.698 -14.384 37.853  1.000 77.711  0 84  ARG HHH C   1 ? 
ATOM   610  O O   . ARG A 1 84  ? -28.924 -15.214 36.937  1.000 73.587  0 84  ARG HHH O   1 ? 
ATOM   611  C CB  . ARG A 1 84  ? -30.086 -12.448 38.566  1.000 82.049  0 84  ARG HHH CB  1 ? 
ATOM   612  C CG  . ARG A 1 84  ? -30.616 -11.047 38.308  1.000 93.602  0 84  ARG HHH CG  1 ? 
ATOM   613  C CD  . ARG A 1 84  ? -32.012 -10.858 38.887  1.000 106.756 0 84  ARG HHH CD  1 ? 
ATOM   614  N NE  . ARG A 1 84  ? -33.070 -10.885 37.873  1.000 124.416 0 84  ARG HHH NE  1 ? 
ATOM   615  C CZ  . ARG A 1 84  ? -34.339 -11.238 38.089  1.000 121.746 0 84  ARG HHH CZ  1 ? 
ATOM   616  N NH1 . ARG A 1 84  ? -34.737 -11.624 39.291  1.000 115.664 0 84  ARG HHH NH1 1 ? 
ATOM   617  N NH2 . ARG A 1 84  ? -35.209 -11.212 37.091  1.000 126.480 0 84  ARG HHH NH2 1 ? 
ATOM   618  N N   . SER A 1 85  ? -28.235 -14.694 39.066  1.000 80.074  0 85  SER HHH N   1 ? 
ATOM   619  C CA  . SER A 1 85  ? -27.983 -16.070 39.559  1.000 78.329  0 85  SER HHH CA  1 ? 
ATOM   620  C C   . SER A 1 85  ? -27.256 -16.863 38.480  1.000 76.802  0 85  SER HHH C   1 ? 
ATOM   621  O O   . SER A 1 85  ? -27.624 -18.027 38.239  1.000 93.037  0 85  SER HHH O   1 ? 
ATOM   622  C CB  . SER A 1 85  ? -29.253 -16.757 39.950  1.000 75.203  0 85  SER HHH CB  1 ? 
ATOM   623  O OG  . SER A 1 85  ? -28.956 -18.038 40.485  1.000 86.275  0 85  SER HHH OG  1 ? 
ATOM   624  N N   . LEU A 1 86  ? -26.256 -16.249 37.861  1.000 73.566  0 86  LEU HHH N   1 ? 
ATOM   625  C CA  . LEU A 1 86  ? -25.632 -16.788 36.629  1.000 75.790  0 86  LEU HHH CA  1 ? 
ATOM   626  C C   . LEU A 1 86  ? -25.129 -18.211 36.878  1.000 69.304  0 86  LEU HHH C   1 ? 
ATOM   627  O O   . LEU A 1 86  ? -24.498 -18.434 37.917  1.000 77.734  0 86  LEU HHH O   1 ? 
ATOM   628  C CB  . LEU A 1 86  ? -24.515 -15.836 36.202  1.000 75.107  0 86  LEU HHH CB  1 ? 
ATOM   629  C CG  . LEU A 1 86  ? -25.017 -14.524 35.609  1.000 71.281  0 86  LEU HHH CG  1 ? 
ATOM   630  C CD1 . LEU A 1 86  ? -23.881 -13.546 35.395  1.000 69.303  0 86  LEU HHH CD1 1 ? 
ATOM   631  C CD2 . LEU A 1 86  ? -25.762 -14.779 34.307  1.000 71.988  0 86  LEU HHH CD2 1 ? 
ATOM   632  N N   . THR A 1 87  ? -25.486 -19.138 35.991  1.000 70.307  0 87  THR HHH N   1 ? 
ATOM   633  C CA  . THR A 1 87  ? -24.994 -20.546 35.946  1.000 75.606  0 87  THR HHH CA  1 ? 
ATOM   634  C C   . THR A 1 87  ? -24.433 -20.802 34.547  1.000 69.278  0 87  THR HHH C   1 ? 
ATOM   635  O O   . THR A 1 87  ? -24.756 -20.019 33.650  1.000 67.883  0 87  THR HHH O   1 ? 
ATOM   636  C CB  . THR A 1 87  ? -26.108 -21.552 36.276  1.000 78.853  0 87  THR HHH CB  1 ? 
ATOM   637  O OG1 . THR A 1 87  ? -27.143 -21.394 35.306  1.000 82.953  0 87  THR HHH OG1 1 ? 
ATOM   638  C CG2 . THR A 1 87  ? -26.705 -21.364 37.656  1.000 81.166  0 87  THR HHH CG2 1 ? 
ATOM   639  N N   . SER A 1 88  ? -23.652 -21.862 34.358  1.000 73.277  0 88  SER HHH N   1 ? 
ATOM   640  C CA  . SER A 1 88  ? -23.108 -22.268 33.036  1.000 76.727  0 88  SER HHH CA  1 ? 
ATOM   641  C C   . SER A 1 88  ? -24.230 -22.289 31.991  1.000 80.612  0 88  SER HHH C   1 ? 
ATOM   642  O O   . SER A 1 88  ? -23.960 -21.900 30.830  1.000 83.758  0 88  SER HHH O   1 ? 
ATOM   643  C CB  . SER A 1 88  ? -22.403 -23.595 33.107  1.000 76.316  0 88  SER HHH CB  1 ? 
ATOM   644  O OG  . SER A 1 88  ? -23.287 -24.616 33.529  1.000 84.829  0 88  SER HHH OG  1 ? 
ATOM   645  N N   . GLU A 1 89  ? -25.447 -22.676 32.395  1.000 78.397  0 89  GLU HHH N   1 ? 
ATOM   646  C CA  . GLU A 1 89  ? -26.633 -22.769 31.500  1.000 81.857  0 89  GLU HHH CA  1 ? 
ATOM   647  C C   . GLU A 1 89  ? -26.876 -21.427 30.798  1.000 75.292  0 89  GLU HHH C   1 ? 
ATOM   648  O O   . GLU A 1 89  ? -27.674 -21.401 29.855  1.000 84.833  0 89  GLU HHH O   1 ? 
ATOM   649  C CB  . GLU A 1 89  ? -27.889 -23.186 32.277  1.000 89.938  0 89  GLU HHH CB  1 ? 
ATOM   650  C CG  . GLU A 1 89  ? -27.785 -24.532 32.982  1.000 100.743 0 89  GLU HHH CG  1 ? 
ATOM   651  C CD  . GLU A 1 89  ? -27.125 -25.642 32.181  1.000 112.158 0 89  GLU HHH CD  1 ? 
ATOM   652  O OE1 . GLU A 1 89  ? -27.726 -26.089 31.185  1.000 116.606 0 89  GLU HHH OE1 1 ? 
ATOM   653  O OE2 . GLU A 1 89  ? -26.001 -26.042 32.546  1.000 132.498 0 89  GLU HHH OE2 1 ? 
ATOM   654  N N   . ASP A 1 90  ? -26.235 -20.350 31.245  1.000 70.233  0 90  ASP HHH N   1 ? 
ATOM   655  C CA  . ASP A 1 90  ? -26.495 -18.988 30.731  1.000 74.599  0 90  ASP HHH CA  1 ? 
ATOM   656  C C   . ASP A 1 90  ? -25.340 -18.562 29.809  1.000 76.037  0 90  ASP HHH C   1 ? 
ATOM   657  O O   . ASP A 1 90  ? -25.388 -17.417 29.302  1.000 69.445  0 90  ASP HHH O   1 ? 
ATOM   658  C CB  . ASP A 1 90  ? -26.771 -18.029 31.896  1.000 84.108  0 90  ASP HHH CB  1 ? 
ATOM   659  C CG  . ASP A 1 90  ? -27.857 -18.472 32.880  1.000 84.960  0 90  ASP HHH CG  1 ? 
ATOM   660  O OD1 . ASP A 1 90  ? -28.883 -19.051 32.441  1.000 84.058  0 90  ASP HHH OD1 1 ? 
ATOM   661  O OD2 . ASP A 1 90  ? -27.677 -18.216 34.094  1.000 83.719  0 90  ASP HHH OD2 1 ? 
ATOM   662  N N   . THR A 1 91  ? -24.345 -19.428 29.570  1.000 76.560  0 91  THR HHH N   1 ? 
ATOM   663  C CA  . THR A 1 91  ? -23.288 -19.167 28.554  1.000 73.216  0 91  THR HHH CA  1 ? 
ATOM   664  C C   . THR A 1 91  ? -23.972 -19.194 27.182  1.000 68.805  0 91  THR HHH C   1 ? 
ATOM   665  O O   . THR A 1 91  ? -24.549 -20.245 26.805  1.000 67.622  0 91  THR HHH O   1 ? 
ATOM   666  C CB  . THR A 1 91  ? -22.108 -20.145 28.610  1.000 78.395  0 91  THR HHH CB  1 ? 
ATOM   667  O OG1 . THR A 1 91  ? -22.600 -21.453 28.329  1.000 110.658 0 91  THR HHH OG1 1 ? 
ATOM   668  C CG2 . THR A 1 91  ? -21.390 -20.193 29.935  1.000 77.398  0 91  THR HHH CG2 1 ? 
ATOM   669  N N   . ALA A 1 92  ? -23.955 -18.055 26.494  1.000 64.260  0 92  ALA HHH N   1 ? 
ATOM   670  C CA  . ALA A 1 92  ? -24.700 -17.812 25.241  1.000 59.665  0 92  ALA HHH CA  1 ? 
ATOM   671  C C   . ALA A 1 92  ? -24.390 -16.414 24.690  1.000 59.611  0 92  ALA HHH C   1 ? 
ATOM   672  O O   . ALA A 1 92  ? -24.048 -15.497 25.456  1.000 51.812  0 92  ALA HHH O   1 ? 
ATOM   673  C CB  . ALA A 1 92  ? -26.182 -17.966 25.481  1.000 57.686  0 92  ALA HHH CB  1 ? 
ATOM   674  N N   . VAL A 1 93  ? -24.525 -16.275 23.377  1.000 60.255  0 93  VAL HHH N   1 ? 
ATOM   675  C CA  . VAL A 1 93  ? -24.648 -14.959 22.709  1.000 56.137  0 93  VAL HHH CA  1 ? 
ATOM   676  C C   . VAL A 1 93  ? -26.058 -14.452 23.000  1.000 57.924  0 93  VAL HHH C   1 ? 
ATOM   677  O O   . VAL A 1 93  ? -27.014 -15.219 22.865  1.000 52.468  0 93  VAL HHH O   1 ? 
ATOM   678  C CB  . VAL A 1 93  ? -24.374 -15.052 21.203  1.000 60.201  0 93  VAL HHH CB  1 ? 
ATOM   679  C CG1 . VAL A 1 93  ? -24.374 -13.673 20.552  1.000 59.453  0 93  VAL HHH CG1 1 ? 
ATOM   680  C CG2 . VAL A 1 93  ? -23.070 -15.788 20.938  1.000 65.228  0 93  VAL HHH CG2 1 ? 
ATOM   681  N N   . TYR A 1 94  ? -26.161 -13.198 23.433  1.000 61.594  0 94  TYR HHH N   1 ? 
ATOM   682  C CA  . TYR A 1 94  ? -27.440 -12.511 23.714  1.000 52.121  0 94  TYR HHH CA  1 ? 
ATOM   683  C C   . TYR A 1 94  ? -27.622 -11.411 22.672  1.000 50.719  0 94  TYR HHH C   1 ? 
ATOM   684  O O   . TYR A 1 94  ? -26.658 -10.687 22.434  1.000 53.519  0 94  TYR HHH O   1 ? 
ATOM   685  C CB  . TYR A 1 94  ? -27.426 -12.055 25.167  1.000 49.911  0 94  TYR HHH CB  1 ? 
ATOM   686  C CG  . TYR A 1 94  ? -27.582 -13.193 26.141  1.000 48.883  0 94  TYR HHH CG  1 ? 
ATOM   687  C CD1 . TYR A 1 94  ? -28.831 -13.717 26.427  1.000 49.941  0 94  TYR HHH CD1 1 ? 
ATOM   688  C CD2 . TYR A 1 94  ? -26.485 -13.767 26.756  1.000 48.585  0 94  TYR HHH CD2 1 ? 
ATOM   689  C CE1 . TYR A 1 94  ? -28.986 -14.779 27.300  1.000 49.820  0 94  TYR HHH CE1 1 ? 
ATOM   690  C CE2 . TYR A 1 94  ? -26.627 -14.808 27.655  1.000 50.947  0 94  TYR HHH CE2 1 ? 
ATOM   691  C CZ  . TYR A 1 94  ? -27.882 -15.326 27.919  1.000 48.940  0 94  TYR HHH CZ  1 ? 
ATOM   692  O OH  . TYR A 1 94  ? -28.046 -16.368 28.787  1.000 58.544  0 94  TYR HHH OH  1 ? 
ATOM   693  N N   . PHE A 1 95  ? -28.799 -11.361 22.035  1.000 54.163  0 95  PHE HHH N   1 ? 
ATOM   694  C CA  . PHE A 1 95  ? -29.153 -10.404 20.953  1.000 58.070  0 95  PHE HHH CA  1 ? 
ATOM   695  C C   . PHE A 1 95  ? -30.307 -9.486  21.378  1.000 60.496  0 95  PHE HHH C   1 ? 
ATOM   696  O O   . PHE A 1 95  ? -31.354 -9.992  21.808  1.000 61.240  0 95  PHE HHH O   1 ? 
ATOM   697  C CB  . PHE A 1 95  ? -29.611 -11.124 19.688  1.000 53.115  0 95  PHE HHH CB  1 ? 
ATOM   698  C CG  . PHE A 1 95  ? -28.583 -11.990 19.015  1.000 56.740  0 95  PHE HHH CG  1 ? 
ATOM   699  C CD1 . PHE A 1 95  ? -27.600 -11.434 18.213  1.000 57.542  0 95  PHE HHH CD1 1 ? 
ATOM   700  C CD2 . PHE A 1 95  ? -28.636 -13.373 19.135  1.000 57.275  0 95  PHE HHH CD2 1 ? 
ATOM   701  C CE1 . PHE A 1 95  ? -26.679 -12.243 17.566  1.000 57.475  0 95  PHE HHH CE1 1 ? 
ATOM   702  C CE2 . PHE A 1 95  ? -27.716 -14.181 18.490  1.000 55.651  0 95  PHE HHH CE2 1 ? 
ATOM   703  C CZ  . PHE A 1 95  ? -26.736 -13.612 17.709  1.000 57.657  0 95  PHE HHH CZ  1 ? 
ATOM   704  N N   . CYS A 1 96  ? -30.134 -8.173  21.211  1.000 60.620  0 96  CYS HHH N   1 ? 
ATOM   705  C CA  . CYS A 1 96  ? -31.255 -7.202  21.171  1.000 66.660  0 96  CYS HHH CA  1 ? 
ATOM   706  C C   . CYS A 1 96  ? -31.661 -7.057  19.708  1.000 60.450  0 96  CYS HHH C   1 ? 
ATOM   707  O O   . CYS A 1 96  ? -30.803 -7.255  18.833  1.000 63.320  0 96  CYS HHH O   1 ? 
ATOM   708  C CB  . CYS A 1 96  ? -30.915 -5.858  21.812  1.000 71.944  0 96  CYS HHH CB  1 ? 
ATOM   709  S SG  . CYS A 1 96  ? -29.567 -4.948  21.013  1.000 86.092  0 96  CYS HHH SG  1 ? 
ATOM   710  N N   . ALA A 1 97  ? -32.932 -6.777  19.462  1.000 58.159  0 97  ALA HHH N   1 ? 
ATOM   711  C CA  . ALA A 1 97  ? -33.483 -6.625  18.106  1.000 63.570  0 97  ALA HHH CA  1 ? 
ATOM   712  C C   . ALA A 1 97  ? -34.702 -5.713  18.168  1.000 63.641  0 97  ALA HHH C   1 ? 
ATOM   713  O O   . ALA A 1 97  ? -35.395 -5.762  19.189  1.000 61.036  0 97  ALA HHH O   1 ? 
ATOM   714  C CB  . ALA A 1 97  ? -33.821 -7.976  17.547  1.000 65.494  0 97  ALA HHH CB  1 ? 
ATOM   715  N N   . ARG A 1 98  ? -34.909 -4.919  17.116  1.000 61.616  0 98  ARG HHH N   1 ? 
ATOM   716  C CA  . ARG A 1 98  ? -36.054 -3.993  16.947  1.000 68.573  0 98  ARG HHH CA  1 ? 
ATOM   717  C C   . ARG A 1 98  ? -37.269 -4.812  16.498  1.000 67.856  0 98  ARG HHH C   1 ? 
ATOM   718  O O   . ARG A 1 98  ? -37.107 -5.618  15.560  1.000 72.130  0 98  ARG HHH O   1 ? 
ATOM   719  C CB  . ARG A 1 98  ? -35.664 -2.918  15.928  1.000 79.607  0 98  ARG HHH CB  1 ? 
ATOM   720  C CG  . ARG A 1 98  ? -36.756 -1.914  15.595  1.000 90.072  0 98  ARG HHH CG  1 ? 
ATOM   721  C CD  . ARG A 1 98  ? -36.273 -0.789  14.691  1.000 100.834 0 98  ARG HHH CD  1 ? 
ATOM   722  N NE  . ARG A 1 98  ? -36.235 -1.156  13.276  1.000 110.120 0 98  ARG HHH NE  1 ? 
ATOM   723  C CZ  . ARG A 1 98  ? -36.275 -0.303  12.247  1.000 105.703 0 98  ARG HHH CZ  1 ? 
ATOM   724  N NH1 . ARG A 1 98  ? -36.357 1.002   12.453  1.000 109.748 0 98  ARG HHH NH1 1 ? 
ATOM   725  N NH2 . ARG A 1 98  ? -36.239 -0.768  11.008  1.000 103.673 0 98  ARG HHH NH2 1 ? 
ATOM   726  N N   . ASN A 1 99  ? -38.435 -4.605  17.124  1.000 66.339  0 99  ASN HHH N   1 ? 
ATOM   727  C CA  . ASN A 1 99  ? -39.685 -5.340  16.805  1.000 66.659  0 99  ASN HHH CA  1 ? 
ATOM   728  C C   . ASN A 1 99  ? -40.502 -4.530  15.807  1.000 65.201  0 99  ASN HHH C   1 ? 
ATOM   729  O O   . ASN A 1 99  ? -40.792 -3.386  16.119  1.000 71.812  0 99  ASN HHH O   1 ? 
ATOM   730  C CB  . ASN A 1 99  ? -40.531 -5.621  18.042  1.000 69.449  0 99  ASN HHH CB  1 ? 
ATOM   731  C CG  . ASN A 1 99  ? -41.494 -6.767  17.834  1.000 72.699  0 99  ASN HHH CG  1 ? 
ATOM   732  O OD1 . ASN A 1 99  ? -42.702 -6.590  17.946  1.000 80.667  0 99  ASN HHH OD1 1 ? 
ATOM   733  N ND2 . ASN A 1 99  ? -40.968 -7.947  17.543  1.000 82.222  0 99  ASN HHH ND2 1 ? 
ATOM   734  N N   . TYR A 1 100 ? -40.871 -5.139  14.676  1.000 76.229  0 100 TYR HHH N   1 ? 
ATOM   735  C CA  . TYR A 1 100 ? -41.705 -4.535  13.606  1.000 73.733  0 100 TYR HHH CA  1 ? 
ATOM   736  C C   . TYR A 1 100 ? -43.115 -4.330  14.163  1.000 77.829  0 100 TYR HHH C   1 ? 
ATOM   737  O O   . TYR A 1 100 ? -43.799 -3.410  13.718  1.000 107.252 0 100 TYR HHH O   1 ? 
ATOM   738  C CB  . TYR A 1 100 ? -41.647 -5.403  12.346  1.000 75.110  0 100 TYR HHH CB  1 ? 
ATOM   739  C CG  . TYR A 1 100 ? -42.593 -5.006  11.243  1.000 82.999  0 100 TYR HHH CG  1 ? 
ATOM   740  C CD1 . TYR A 1 100 ? -43.512 -5.904  10.746  1.000 85.619  0 100 TYR HHH CD1 1 ? 
ATOM   741  C CD2 . TYR A 1 100 ? -42.612 -3.726  10.728  1.000 92.494  0 100 TYR HHH CD2 1 ? 
ATOM   742  C CE1 . TYR A 1 100 ? -44.378 -5.564  9.727   1.000 84.792  0 100 TYR HHH CE1 1 ? 
ATOM   743  C CE2 . TYR A 1 100 ? -43.510 -3.352  9.747   1.000 97.375  0 100 TYR HHH CE2 1 ? 
ATOM   744  C CZ  . TYR A 1 100 ? -44.391 -4.281  9.234   1.000 91.893  0 100 TYR HHH CZ  1 ? 
ATOM   745  O OH  . TYR A 1 100 ? -45.289 -3.963  8.258   1.000 105.284 0 100 TYR HHH OH  1 ? 
ATOM   746  N N   . ARG A 1 101 ? -43.531 -5.162  15.113  1.000 77.067  0 101 ARG HHH N   1 ? 
ATOM   747  C CA  . ARG A 1 101 ? -44.795 -5.011  15.893  1.000 73.594  0 101 ARG HHH CA  1 ? 
ATOM   748  C C   . ARG A 1 101 ? -46.008 -5.468  15.079  1.000 65.429  0 101 ARG HHH C   1 ? 
ATOM   749  O O   . ARG A 1 101 ? -46.826 -6.190  15.658  1.000 70.260  0 101 ARG HHH O   1 ? 
ATOM   750  C CB  . ARG A 1 101 ? -45.005 -3.588  16.428  1.000 82.520  0 101 ARG HHH CB  1 ? 
ATOM   751  C CG  . ARG A 1 101 ? -46.343 -3.399  17.130  1.000 95.147  0 101 ARG HHH CG  1 ? 
ATOM   752  C CD  . ARG A 1 101 ? -46.515 -2.062  17.827  1.000 107.891 0 101 ARG HHH CD  1 ? 
ATOM   753  N NE  . ARG A 1 101 ? -45.619 -1.814  18.955  1.000 122.213 0 101 ARG HHH NE  1 ? 
ATOM   754  C CZ  . ARG A 1 101 ? -45.695 -2.398  20.160  1.000 134.463 0 101 ARG HHH CZ  1 ? 
ATOM   755  N NH1 . ARG A 1 101 ? -44.845 -2.062  21.105  1.000 147.556 0 101 ARG HHH NH1 1 ? 
ATOM   756  N NH2 . ARG A 1 101 ? -46.609 -3.310  20.437  1.000 129.373 0 101 ARG HHH NH2 1 ? 
ATOM   757  N N   . TRP A 1 102 ? -46.167 -5.065  13.818  1.000 64.424  0 102 TRP HHH N   1 ? 
ATOM   758  C CA  . TRP A 1 102 ? -47.347 -5.480  13.019  1.000 62.701  0 102 TRP HHH CA  1 ? 
ATOM   759  C C   . TRP A 1 102 ? -47.328 -7.009  12.872  1.000 62.754  0 102 TRP HHH C   1 ? 
ATOM   760  O O   . TRP A 1 102 ? -48.385 -7.659  12.996  1.000 67.663  0 102 TRP HHH O   1 ? 
ATOM   761  C CB  . TRP A 1 102 ? -47.390 -4.774  11.663  1.000 63.263  0 102 TRP HHH CB  1 ? 
ATOM   762  C CG  . TRP A 1 102 ? -48.567 -5.229  10.854  1.000 66.615  0 102 TRP HHH CG  1 ? 
ATOM   763  C CD1 . TRP A 1 102 ? -48.628 -6.257  9.945   1.000 70.140  0 102 TRP HHH CD1 1 ? 
ATOM   764  C CD2 . TRP A 1 102 ? -49.896 -4.701  10.950  1.000 61.706  0 102 TRP HHH CD2 1 ? 
ATOM   765  N NE1 . TRP A 1 102 ? -49.907 -6.430  9.491   1.000 70.114  0 102 TRP HHH NE1 1 ? 
ATOM   766  C CE2 . TRP A 1 102 ? -50.701 -5.466  10.075  1.000 68.310  0 102 TRP HHH CE2 1 ? 
ATOM   767  C CE3 . TRP A 1 102 ? -50.470 -3.654  11.680  1.000 56.425  0 102 TRP HHH CE3 1 ? 
ATOM   768  C CZ2 . TRP A 1 102 ? -52.059 -5.198  9.919   1.000 67.659  0 102 TRP HHH CZ2 1 ? 
ATOM   769  C CZ3 . TRP A 1 102 ? -51.811 -3.398  11.522  1.000 59.796  0 102 TRP HHH CZ3 1 ? 
ATOM   770  C CH2 . TRP A 1 102 ? -52.591 -4.157  10.648  1.000 64.329  0 102 TRP HHH CH2 1 ? 
ATOM   771  N N   . PHE A 1 103 ? -46.152 -7.577  12.642  1.000 63.036  0 103 PHE HHH N   1 ? 
ATOM   772  C CA  . PHE A 1 103 ? -45.976 -9.043  12.522  1.000 61.886  0 103 PHE HHH CA  1 ? 
ATOM   773  C C   . PHE A 1 103 ? -45.087 -9.533  13.653  1.000 65.758  0 103 PHE HHH C   1 ? 
ATOM   774  O O   . PHE A 1 103 ? -44.693 -10.687 13.612  1.000 62.619  0 103 PHE HHH O   1 ? 
ATOM   775  C CB  . PHE A 1 103 ? -45.343 -9.393  11.184  1.000 57.311  0 103 PHE HHH CB  1 ? 
ATOM   776  C CG  . PHE A 1 103 ? -46.281 -9.313  10.019  1.000 54.648  0 103 PHE HHH CG  1 ? 
ATOM   777  C CD1 . PHE A 1 103 ? -47.429 -10.068 10.010  1.000 61.085  0 103 PHE HHH CD1 1 ? 
ATOM   778  C CD2 . PHE A 1 103 ? -46.005 -8.510  8.927   1.000 57.241  0 103 PHE HHH CD2 1 ? 
ATOM   779  C CE1 . PHE A 1 103 ? -48.282 -10.023 8.920   1.000 65.884  0 103 PHE HHH CE1 1 ? 
ATOM   780  C CE2 . PHE A 1 103 ? -46.885 -8.422  7.864   1.000 56.899  0 103 PHE HHH CE2 1 ? 
ATOM   781  C CZ  . PHE A 1 103 ? -48.015 -9.191  7.857   1.000 63.443  0 103 PHE HHH CZ  1 ? 
ATOM   782  N N   . GLY A 1 104 ? -44.770 -8.655  14.606  1.000 69.176  0 104 GLY HHH N   1 ? 
ATOM   783  C CA  . GLY A 1 104 ? -43.894 -8.995  15.732  1.000 67.640  0 104 GLY HHH CA  1 ? 
ATOM   784  C C   . GLY A 1 104 ? -42.603 -9.593  15.218  1.000 66.467  0 104 GLY HHH C   1 ? 
ATOM   785  O O   . GLY A 1 104 ? -42.156 -10.623 15.751  1.000 61.148  0 104 GLY HHH O   1 ? 
ATOM   786  N N   . ALA A 1 105 ? -42.004 -8.966  14.212  1.000 67.527  0 105 ALA HHH N   1 ? 
ATOM   787  C CA  . ALA A 1 105 ? -40.790 -9.497  13.559  1.000 64.699  0 105 ALA HHH CA  1 ? 
ATOM   788  C C   . ALA A 1 105 ? -39.552 -8.739  14.059  1.000 65.391  0 105 ALA HHH C   1 ? 
ATOM   789  O O   . ALA A 1 105 ? -39.512 -7.493  13.984  1.000 69.796  0 105 ALA HHH O   1 ? 
ATOM   790  C CB  . ALA A 1 105 ? -40.961 -9.430  12.064  1.000 59.747  0 105 ALA HHH CB  1 ? 
ATOM   791  N N   . MET A 1 106 ? -38.551 -9.457  14.558  1.000 64.043  0 106 MET HHH N   1 ? 
ATOM   792  C CA  . MET A 1 106 ? -37.255 -8.825  14.886  1.000 64.954  0 106 MET HHH CA  1 ? 
ATOM   793  C C   . MET A 1 106 ? -36.648 -8.338  13.569  1.000 62.741  0 106 MET HHH C   1 ? 
ATOM   794  O O   . MET A 1 106 ? -36.186 -9.203  12.827  1.000 57.977  0 106 MET HHH O   1 ? 
ATOM   795  C CB  . MET A 1 106 ? -36.317 -9.816  15.568  1.000 69.438  0 106 MET HHH CB  1 ? 
ATOM   796  C CG  . MET A 1 106 ? -36.536 -9.907  17.055  1.000 69.209  0 106 MET HHH CG  1 ? 
ATOM   797  S SD  . MET A 1 106 ? -38.033 -10.773 17.457  1.000 81.617  0 106 MET HHH SD  1 ? 
ATOM   798  C CE  . MET A 1 106 ? -37.412 -12.409 17.849  1.000 66.228  0 106 MET HHH CE  1 ? 
ATOM   799  N N   . ASP A 1 107 ? -36.716 -7.028  13.267  1.000 64.785  0 107 ASP HHH N   1 ? 
ATOM   800  C CA  . ASP A 1 107 ? -36.405 -6.501  11.905  1.000 66.350  0 107 ASP HHH CA  1 ? 
ATOM   801  C C   . ASP A 1 107 ? -34.917 -6.135  11.799  1.000 61.147  0 107 ASP HHH C   1 ? 
ATOM   802  O O   . ASP A 1 107 ? -34.349 -6.483  10.767  1.000 50.755  0 107 ASP HHH O   1 ? 
ATOM   803  C CB  . ASP A 1 107 ? -37.372 -5.399  11.463  1.000 66.893  0 107 ASP HHH CB  1 ? 
ATOM   804  C CG  . ASP A 1 107 ? -37.173 -4.074  12.158  1.000 74.936  0 107 ASP HHH CG  1 ? 
ATOM   805  O OD1 . ASP A 1 107 ? -36.112 -3.445  11.939  1.000 88.111  0 107 ASP HHH OD1 1 ? 
ATOM   806  O OD2 . ASP A 1 107 ? -38.073 -3.691  12.921  1.000 88.327  0 107 ASP HHH OD2 1 ? 
ATOM   807  N N   . HIS A 1 108 ? -34.319 -5.472  12.806  1.000 69.630  0 108 HIS HHH N   1 ? 
ATOM   808  C CA  A HIS A 1 108 ? -32.852 -5.188  12.874  0.500 65.477  0 108 HIS HHH CA  1 ? 
ATOM   809  C CA  B HIS A 1 108 ? -32.859 -5.179  12.881  0.500 69.623  0 108 HIS HHH CA  1 ? 
ATOM   810  C C   . HIS A 1 108 ? -32.290 -5.755  14.185  1.000 65.667  0 108 HIS HHH C   1 ? 
ATOM   811  O O   . HIS A 1 108 ? -32.871 -5.500  15.252  1.000 64.083  0 108 HIS HHH O   1 ? 
ATOM   812  C CB  A HIS A 1 108 ? -32.534 -3.686  12.692  0.500 62.182  0 108 HIS HHH CB  1 ? 
ATOM   813  C CB  B HIS A 1 108 ? -32.594 -3.671  12.716  0.500 71.466  0 108 HIS HHH CB  1 ? 
ATOM   814  C CG  A HIS A 1 108 ? -31.233 -3.407  11.999  0.500 58.077  0 108 HIS HHH CG  1 ? 
ATOM   815  C CG  B HIS A 1 108 ? -33.018 -3.125  11.390  0.500 72.792  0 108 HIS HHH CG  1 ? 
ATOM   816  N ND1 A HIS A 1 108 ? -29.995 -3.544  12.622  0.500 55.071  0 108 HIS HHH ND1 1 ? 
ATOM   817  N ND1 B HIS A 1 108 ? -33.244 -1.787  11.186  0.500 76.921  0 108 HIS HHH ND1 1 ? 
ATOM   818  C CD2 A HIS A 1 108 ? -30.965 -2.987  10.742  0.500 54.472  0 108 HIS HHH CD2 1 ? 
ATOM   819  C CD2 B HIS A 1 108 ? -33.286 -3.733  10.213  0.500 71.535  0 108 HIS HHH CD2 1 ? 
ATOM   820  C CE1 A HIS A 1 108 ? -29.033 -3.228  11.777  0.500 51.898  0 108 HIS HHH CE1 1 ? 
ATOM   821  C CE1 B HIS A 1 108 ? -33.608 -1.580  9.939   0.500 76.414  0 108 HIS HHH CE1 1 ? 
ATOM   822  N NE2 A HIS A 1 108 ? -29.601 -2.887  10.620  0.500 54.214  0 108 HIS HHH NE2 1 ? 
ATOM   823  N NE2 B HIS A 1 108 ? -33.655 -2.763  9.323   0.500 74.152  0 108 HIS HHH NE2 1 ? 
ATOM   824  N N   . TRP A 1 109 ? -31.197 -6.505  14.085  1.000 71.589  0 109 TRP HHH N   1 ? 
ATOM   825  C CA  . TRP A 1 109 ? -30.577 -7.213  15.231  1.000 71.941  0 109 TRP HHH CA  1 ? 
ATOM   826  C C   . TRP A 1 109 ? -29.272 -6.526  15.641  1.000 74.342  0 109 TRP HHH C   1 ? 
ATOM   827  O O   . TRP A 1 109 ? -28.583 -5.958  14.760  1.000 74.211  0 109 TRP HHH O   1 ? 
ATOM   828  C CB  . TRP A 1 109 ? -30.324 -8.678  14.865  1.000 73.217  0 109 TRP HHH CB  1 ? 
ATOM   829  C CG  . TRP A 1 109 ? -31.556 -9.502  14.683  1.000 63.738  0 109 TRP HHH CG  1 ? 
ATOM   830  C CD1 . TRP A 1 109 ? -32.504 -9.350  13.722  1.000 62.014  0 109 TRP HHH CD1 1 ? 
ATOM   831  C CD2 . TRP A 1 109 ? -31.967 -10.624 15.478  1.000 56.619  0 109 TRP HHH CD2 1 ? 
ATOM   832  N NE1 . TRP A 1 109 ? -33.481 -10.291 13.874  1.000 64.397  0 109 TRP HHH NE1 1 ? 
ATOM   833  C CE2 . TRP A 1 109 ? -33.169 -11.099 14.931  1.000 57.456  0 109 TRP HHH CE2 1 ? 
ATOM   834  C CE3 . TRP A 1 109 ? -31.440 -11.273 16.589  1.000 55.801  0 109 TRP HHH CE3 1 ? 
ATOM   835  C CZ2 . TRP A 1 109 ? -33.846 -12.195 15.446  1.000 57.439  0 109 TRP HHH CZ2 1 ? 
ATOM   836  C CZ3 . TRP A 1 109 ? -32.117 -12.352 17.110  1.000 59.289  0 109 TRP HHH CZ3 1 ? 
ATOM   837  C CH2 . TRP A 1 109 ? -33.300 -12.809 16.544  1.000 58.230  0 109 TRP HHH CH2 1 ? 
ATOM   838  N N   . GLY A 1 110 ? -28.944 -6.616  16.933  1.000 70.474  0 110 GLY HHH N   1 ? 
ATOM   839  C CA  . GLY A 1 110 ? -27.637 -6.238  17.488  1.000 64.932  0 110 GLY HHH CA  1 ? 
ATOM   840  C C   . GLY A 1 110 ? -26.597 -7.279  17.117  1.000 69.131  0 110 GLY HHH C   1 ? 
ATOM   841  O O   . GLY A 1 110 ? -26.976 -8.430  16.911  1.000 64.225  0 110 GLY HHH O   1 ? 
ATOM   842  N N   . GLN A 1 111 ? -25.324 -6.889  17.014  1.000 77.463  0 111 GLN HHH N   1 ? 
ATOM   843  C CA  . GLN A 1 111 ? -24.187 -7.812  16.751  1.000 79.213  0 111 GLN HHH CA  1 ? 
ATOM   844  C C   . GLN A 1 111 ? -24.259 -9.025  17.697  1.000 77.868  0 111 GLN HHH C   1 ? 
ATOM   845  O O   . GLN A 1 111 ? -23.813 -10.126 17.289  1.000 74.507  0 111 GLN HHH O   1 ? 
ATOM   846  C CB  . GLN A 1 111 ? -22.861 -7.071  16.905  1.000 88.435  0 111 GLN HHH CB  1 ? 
ATOM   847  C CG  . GLN A 1 111 ? -22.639 -6.487  18.295  1.000 104.489 0 111 GLN HHH CG  1 ? 
ATOM   848  C CD  . GLN A 1 111 ? -23.022 -5.028  18.382  1.000 122.297 0 111 GLN HHH CD  1 ? 
ATOM   849  O OE1 . GLN A 1 111 ? -24.170 -4.640  18.158  1.000 123.992 0 111 GLN HHH OE1 1 ? 
ATOM   850  N NE2 . GLN A 1 111 ? -22.047 -4.196  18.712  1.000 141.504 0 111 GLN HHH NE2 1 ? 
ATOM   851  N N   . GLY A 1 112 ? -24.796 -8.835  18.910  1.000 70.685  0 112 GLY HHH N   1 ? 
ATOM   852  C CA  . GLY A 1 112 ? -24.883 -9.869  19.956  1.000 71.135  0 112 GLY HHH CA  1 ? 
ATOM   853  C C   . GLY A 1 112 ? -23.726 -9.769  20.934  1.000 69.473  0 112 GLY HHH C   1 ? 
ATOM   854  O O   . GLY A 1 112 ? -22.603 -9.474  20.508  1.000 79.706  0 112 GLY HHH O   1 ? 
ATOM   855  N N   . THR A 1 113 ? -23.989 -9.983  22.218  1.000 69.403  0 113 THR HHH N   1 ? 
ATOM   856  C CA  . THR A 1 113 ? -22.970 -9.972  23.297  1.000 65.298  0 113 THR HHH CA  1 ? 
ATOM   857  C C   . THR A 1 113 ? -22.777 -11.422 23.735  1.000 64.130  0 113 THR HHH C   1 ? 
ATOM   858  O O   . THR A 1 113 ? -23.741 -11.996 24.280  1.000 56.559  0 113 THR HHH O   1 ? 
ATOM   859  C CB  . THR A 1 113 ? -23.410 -9.089  24.473  1.000 65.894  0 113 THR HHH CB  1 ? 
ATOM   860  O OG1 . THR A 1 113 ? -23.480 -7.733  24.037  1.000 64.423  0 113 THR HHH OG1 1 ? 
ATOM   861  C CG2 . THR A 1 113 ? -22.482 -9.202  25.664  1.000 69.049  0 113 THR HHH CG2 1 ? 
ATOM   862  N N   . SER A 1 114 ? -21.612 -12.011 23.471  1.000 64.700  0 114 SER HHH N   1 ? 
ATOM   863  C CA  . SER A 1 114 ? -21.302 -13.392 23.912  1.000 66.522  0 114 SER HHH CA  1 ? 
ATOM   864  C C   . SER A 1 114 ? -20.983 -13.359 25.403  1.000 65.939  0 114 SER HHH C   1 ? 
ATOM   865  O O   . SER A 1 114 ? -19.962 -12.796 25.758  1.000 69.921  0 114 SER HHH O   1 ? 
ATOM   866  C CB  . SER A 1 114 ? -20.168 -13.989 23.153  1.000 70.462  0 114 SER HHH CB  1 ? 
ATOM   867  O OG  . SER A 1 114 ? -19.569 -15.018 23.927  1.000 71.571  0 114 SER HHH OG  1 ? 
ATOM   868  N N   . VAL A 1 115 ? -21.818 -13.965 26.236  1.000 68.352  0 115 VAL HHH N   1 ? 
ATOM   869  C CA  . VAL A 1 115 ? -21.591 -14.012 27.708  1.000 71.221  0 115 VAL HHH CA  1 ? 
ATOM   870  C C   . VAL A 1 115 ? -21.113 -15.418 28.071  1.000 66.778  0 115 VAL HHH C   1 ? 
ATOM   871  O O   . VAL A 1 115 ? -21.817 -16.381 27.757  1.000 74.444  0 115 VAL HHH O   1 ? 
ATOM   872  C CB  . VAL A 1 115 ? -22.852 -13.602 28.499  1.000 72.400  0 115 VAL HHH CB  1 ? 
ATOM   873  C CG1 . VAL A 1 115 ? -22.718 -13.909 29.985  1.000 70.526  0 115 VAL HHH CG1 1 ? 
ATOM   874  C CG2 . VAL A 1 115 ? -23.187 -12.131 28.291  1.000 71.316  0 115 VAL HHH CG2 1 ? 
ATOM   875  N N   . THR A 1 116 ? -19.959 -15.515 28.722  1.000 67.972  0 116 THR HHH N   1 ? 
ATOM   876  C CA  . THR A 1 116 ? -19.429 -16.779 29.288  1.000 75.545  0 116 THR HHH CA  1 ? 
ATOM   877  C C   . THR A 1 116 ? -19.482 -16.682 30.811  1.000 72.855  0 116 THR HHH C   1 ? 
ATOM   878  O O   . THR A 1 116 ? -18.893 -15.745 31.360  1.000 65.194  0 116 THR HHH O   1 ? 
ATOM   879  C CB  . THR A 1 116 ? -18.014 -17.063 28.772  1.000 77.607  0 116 THR HHH CB  1 ? 
ATOM   880  O OG1 . THR A 1 116 ? -18.067 -16.829 27.367  1.000 81.416  0 116 THR HHH OG1 1 ? 
ATOM   881  C CG2 . THR A 1 116 ? -17.541 -18.471 29.063  1.000 75.108  0 116 THR HHH CG2 1 ? 
ATOM   882  N N   . VAL A 1 117 ? -20.173 -17.617 31.454  1.000 81.221  0 117 VAL HHH N   1 ? 
ATOM   883  C CA  . VAL A 1 117 ? -20.278 -17.679 32.935  1.000 89.464  0 117 VAL HHH CA  1 ? 
ATOM   884  C C   . VAL A 1 117 ? -19.497 -18.902 33.418  1.000 88.481  0 117 VAL HHH C   1 ? 
ATOM   885  O O   . VAL A 1 117 ? -20.023 -20.028 33.379  1.000 87.159  0 117 VAL HHH O   1 ? 
ATOM   886  C CB  . VAL A 1 117 ? -21.743 -17.637 33.406  1.000 99.060  0 117 VAL HHH CB  1 ? 
ATOM   887  C CG1 . VAL A 1 117 ? -22.543 -18.852 32.980  1.000 99.513  0 117 VAL HHH CG1 1 ? 
ATOM   888  C CG2 . VAL A 1 117 ? -21.827 -17.440 34.910  1.000 107.901 0 117 VAL HHH CG2 1 ? 
ATOM   889  N N   . SER A 1 118 ? -18.242 -18.669 33.792  1.000 90.297  0 118 SER HHH N   1 ? 
ATOM   890  C CA  . SER A 1 118 ? -17.400 -19.628 34.540  1.000 92.589  0 118 SER HHH CA  1 ? 
ATOM   891  C C   . SER A 1 118 ? -16.524 -18.856 35.524  1.000 91.808  0 118 SER HHH C   1 ? 
ATOM   892  O O   . SER A 1 118 ? -16.490 -17.607 35.456  1.000 84.463  0 118 SER HHH O   1 ? 
ATOM   893  C CB  . SER A 1 118 ? -16.579 -20.464 33.611  1.000 98.897  0 118 SER HHH CB  1 ? 
ATOM   894  O OG  . SER A 1 118 ? -15.869 -19.635 32.707  1.000 107.979 0 118 SER HHH OG  1 ? 
ATOM   895  N N   . SER A 1 119 ? -15.875 -19.604 36.414  1.000 97.226  0 119 SER HHH N   1 ? 
ATOM   896  C CA  . SER A 1 119 ? -14.961 -19.121 37.481  1.000 95.956  0 119 SER HHH CA  1 ? 
ATOM   897  C C   . SER A 1 119 ? -13.560 -18.931 36.893  1.000 91.071  0 119 SER HHH C   1 ? 
ATOM   898  O O   . SER A 1 119 ? -13.067 -19.872 36.253  1.000 96.296  0 119 SER HHH O   1 ? 
ATOM   899  C CB  . SER A 1 119 ? -14.943 -20.116 38.614  1.000 98.791  0 119 SER HHH CB  1 ? 
ATOM   900  O OG  . SER A 1 119 ? -16.253 -20.602 38.880  1.000 97.357  0 119 SER HHH OG  1 ? 
ATOM   901  N N   . THR A 1 120 ? -12.940 -17.767 37.080  1.000 82.989  0 120 THR HHH N   1 ? 
ATOM   902  C CA  . THR A 1 120 ? -11.549 -17.537 36.619  1.000 83.094  0 120 THR HHH CA  1 ? 
ATOM   903  C C   . THR A 1 120 ? -10.641 -18.211 37.657  1.000 81.839  0 120 THR HHH C   1 ? 
ATOM   904  O O   . THR A 1 120 ? -10.877 -18.000 38.854  1.000 80.427  0 120 THR HHH O   1 ? 
ATOM   905  C CB  . THR A 1 120 ? -11.255 -16.052 36.335  1.000 80.891  0 120 THR HHH CB  1 ? 
ATOM   906  O OG1 . THR A 1 120 ? -10.617 -15.455 37.464  1.000 76.542  0 120 THR HHH OG1 1 ? 
ATOM   907  C CG2 . THR A 1 120 ? -12.481 -15.251 35.944  1.000 78.155  0 120 THR HHH CG2 1 ? 
ATOM   908  N N   . LYS A 1 121 ? -9.664  -19.009 37.216  1.000 82.765  0 121 LYS HHH N   1 ? 
ATOM   909  C CA  . LYS A 1 121 ? -8.752  -19.761 38.118  1.000 81.022  0 121 LYS HHH CA  1 ? 
ATOM   910  C C   . LYS A 1 121 ? -7.278  -19.471 37.777  1.000 83.140  0 121 LYS HHH C   1 ? 
ATOM   911  O O   . LYS A 1 121 ? -6.868  -19.669 36.609  1.000 80.424  0 121 LYS HHH O   1 ? 
ATOM   912  C CB  . LYS A 1 121 ? -9.085  -21.252 38.044  1.000 79.766  0 121 LYS HHH CB  1 ? 
ATOM   913  C CG  . LYS A 1 121 ? -8.208  -22.138 38.912  1.000 87.049  0 121 LYS HHH CG  1 ? 
ATOM   914  C CD  . LYS A 1 121 ? -8.579  -23.599 38.859  1.000 99.954  0 121 LYS HHH CD  1 ? 
ATOM   915  C CE  . LYS A 1 121 ? -7.762  -24.437 39.822  1.000 109.009 0 121 LYS HHH CE  1 ? 
ATOM   916  N NZ  . LYS A 1 121 ? -8.071  -25.880 39.677  1.000 112.521 0 121 LYS HHH NZ  1 ? 
ATOM   917  N N   . GLY A 1 122 ? -6.507  -19.021 38.777  1.000 83.154  0 122 GLY HHH N   1 ? 
ATOM   918  C CA  . GLY A 1 122 ? -5.031  -18.982 38.757  1.000 76.403  0 122 GLY HHH CA  1 ? 
ATOM   919  C C   . GLY A 1 122 ? -4.431  -20.378 38.577  1.000 71.319  0 122 GLY HHH C   1 ? 
ATOM   920  O O   . GLY A 1 122 ? -5.052  -21.381 38.924  1.000 64.536  0 122 GLY HHH O   1 ? 
ATOM   921  N N   . PRO A 1 123 ? -3.216  -20.487 37.997  1.000 66.611  0 123 PRO HHH N   1 ? 
ATOM   922  C CA  . PRO A 1 123 ? -2.564  -21.784 37.792  1.000 63.988  0 123 PRO HHH CA  1 ? 
ATOM   923  C C   . PRO A 1 123 ? -1.891  -22.422 39.017  1.000 65.862  0 123 PRO HHH C   1 ? 
ATOM   924  O O   . PRO A 1 123 ? -1.272  -21.720 39.775  1.000 70.735  0 123 PRO HHH O   1 ? 
ATOM   925  C CB  . PRO A 1 123 ? -1.446  -21.427 36.792  1.000 65.896  0 123 PRO HHH CB  1 ? 
ATOM   926  C CG  . PRO A 1 123 ? -1.102  -19.986 37.101  1.000 64.358  0 123 PRO HHH CG  1 ? 
ATOM   927  C CD  . PRO A 1 123 ? -2.437  -19.361 37.449  1.000 65.727  0 123 PRO HHH CD  1 ? 
ATOM   928  N N   . SER A 1 124 ? -1.964  -23.745 39.148  1.000 70.535  0 124 SER HHH N   1 ? 
ATOM   929  C CA  . SER A 1 124 ? -0.979  -24.528 39.939  1.000 75.547  0 124 SER HHH CA  1 ? 
ATOM   930  C C   . SER A 1 124 ? 0.326   -24.504 39.142  1.000 74.514  0 124 SER HHH C   1 ? 
ATOM   931  O O   . SER A 1 124 ? 0.243   -24.470 37.909  1.000 77.669  0 124 SER HHH O   1 ? 
ATOM   932  C CB  . SER A 1 124 ? -1.444  -25.927 40.220  1.000 74.732  0 124 SER HHH CB  1 ? 
ATOM   933  O OG  . SER A 1 124 ? -2.808  -25.942 40.603  1.000 80.021  0 124 SER HHH OG  1 ? 
ATOM   934  N N   . VAL A 1 125 ? 1.476   -24.412 39.808  1.000 76.057  0 125 VAL HHH N   1 ? 
ATOM   935  C CA  . VAL A 1 125 ? 2.789   -24.243 39.120  1.000 70.035  0 125 VAL HHH CA  1 ? 
ATOM   936  C C   . VAL A 1 125 ? 3.756   -25.272 39.700  1.000 68.910  0 125 VAL HHH C   1 ? 
ATOM   937  O O   . VAL A 1 125 ? 4.287   -25.050 40.782  1.000 73.137  0 125 VAL HHH O   1 ? 
ATOM   938  C CB  . VAL A 1 125 ? 3.329   -22.804 39.223  1.000 64.451  0 125 VAL HHH CB  1 ? 
ATOM   939  C CG1 . VAL A 1 125 ? 4.683   -22.677 38.543  1.000 61.605  0 125 VAL HHH CG1 1 ? 
ATOM   940  C CG2 . VAL A 1 125 ? 2.349   -21.779 38.664  1.000 59.520  0 125 VAL HHH CG2 1 ? 
ATOM   941  N N   . PHE A 1 126 ? 3.940   -26.378 38.989  1.000 71.378  0 126 PHE HHH N   1 ? 
ATOM   942  C CA  . PHE A 1 126 ? 4.826   -27.493 39.388  1.000 75.288  0 126 PHE HHH CA  1 ? 
ATOM   943  C C   . PHE A 1 126 ? 6.136   -27.323 38.639  1.000 74.931  0 126 PHE HHH C   1 ? 
ATOM   944  O O   . PHE A 1 126 ? 6.114   -26.913 37.490  1.000 77.186  0 126 PHE HHH O   1 ? 
ATOM   945  C CB  . PHE A 1 126 ? 4.134   -28.826 39.110  1.000 77.749  0 126 PHE HHH CB  1 ? 
ATOM   946  C CG  . PHE A 1 126 ? 2.721   -28.844 39.625  1.000 81.162  0 126 PHE HHH CG  1 ? 
ATOM   947  C CD1 . PHE A 1 126 ? 2.474   -28.921 40.984  1.000 83.154  0 126 PHE HHH CD1 1 ? 
ATOM   948  C CD2 . PHE A 1 126 ? 1.646   -28.716 38.759  1.000 83.714  0 126 PHE HHH CD2 1 ? 
ATOM   949  C CE1 . PHE A 1 126 ? 1.174   -28.915 41.464  1.000 88.254  0 126 PHE HHH CE1 1 ? 
ATOM   950  C CE2 . PHE A 1 126 ? 0.347   -28.696 39.237  1.000 86.913  0 126 PHE HHH CE2 1 ? 
ATOM   951  C CZ  . PHE A 1 126 ? 0.116   -28.798 40.593  1.000 90.135  0 126 PHE HHH CZ  1 ? 
ATOM   952  N N   . PRO A 1 127 ? 7.294   -27.627 39.269  1.000 82.049  0 127 PRO HHH N   1 ? 
ATOM   953  C CA  . PRO A 1 127 ? 8.600   -27.436 38.647  1.000 76.118  0 127 PRO HHH CA  1 ? 
ATOM   954  C C   . PRO A 1 127 ? 9.022   -28.639 37.802  1.000 76.611  0 127 PRO HHH C   1 ? 
ATOM   955  O O   . PRO A 1 127 ? 8.640   -29.753 38.118  1.000 87.495  0 127 PRO HHH O   1 ? 
ATOM   956  C CB  . PRO A 1 127 ? 9.524   -27.349 39.863  1.000 79.384  0 127 PRO HHH CB  1 ? 
ATOM   957  C CG  . PRO A 1 127 ? 8.904   -28.329 40.843  1.000 81.678  0 127 PRO HHH CG  1 ? 
ATOM   958  C CD  . PRO A 1 127 ? 7.411   -28.199 40.622  1.000 81.711  0 127 PRO HHH CD  1 ? 
ATOM   959  N N   . LEU A 1 128 ? 9.828   -28.382 36.781  1.000 76.176  0 128 LEU HHH N   1 ? 
ATOM   960  C CA  . LEU A 1 128 ? 10.442  -29.426 35.933  1.000 70.817  0 128 LEU HHH CA  1 ? 
ATOM   961  C C   . LEU A 1 128 ? 11.933  -29.405 36.212  1.000 81.070  0 128 LEU HHH C   1 ? 
ATOM   962  O O   . LEU A 1 128 ? 12.660  -28.648 35.539  1.000 88.199  0 128 LEU HHH O   1 ? 
ATOM   963  C CB  . LEU A 1 128 ? 10.127  -29.133 34.472  1.000 68.540  0 128 LEU HHH CB  1 ? 
ATOM   964  C CG  . LEU A 1 128 ? 8.640   -28.990 34.173  1.000 73.038  0 128 LEU HHH CG  1 ? 
ATOM   965  C CD1 . LEU A 1 128 ? 8.429   -28.434 32.778  1.000 80.436  0 128 LEU HHH CD1 1 ? 
ATOM   966  C CD2 . LEU A 1 128 ? 7.924   -30.321 34.333  1.000 76.146  0 128 LEU HHH CD2 1 ? 
ATOM   967  N N   . ALA A 1 129 ? 12.343  -30.179 37.215  1.000 91.842  0 129 ALA HHH N   1 ? 
ATOM   968  C CA  . ALA A 1 129 ? 13.741  -30.251 37.684  1.000 98.712  0 129 ALA HHH CA  1 ? 
ATOM   969  C C   . ALA A 1 129 ? 14.544  -31.100 36.701  1.000 99.578  0 129 ALA HHH C   1 ? 
ATOM   970  O O   . ALA A 1 129 ? 14.054  -32.103 36.180  1.000 85.885  0 129 ALA HHH O   1 ? 
ATOM   971  C CB  . ALA A 1 129 ? 13.783  -30.793 39.092  1.000 102.777 0 129 ALA HHH CB  1 ? 
ATOM   972  N N   . PRO A 1 130 ? 15.801  -30.707 36.406  1.000 109.474 0 130 PRO HHH N   1 ? 
ATOM   973  C CA  . PRO A 1 130 ? 16.691  -31.525 35.584  1.000 115.576 0 130 PRO HHH CA  1 ? 
ATOM   974  C C   . PRO A 1 130 ? 17.487  -32.560 36.397  1.000 120.660 0 130 PRO HHH C   1 ? 
ATOM   975  O O   . PRO A 1 130 ? 17.640  -32.360 37.588  1.000 120.300 0 130 PRO HHH O   1 ? 
ATOM   976  C CB  . PRO A 1 130 ? 17.619  -30.448 35.012  1.000 118.272 0 130 PRO HHH CB  1 ? 
ATOM   977  C CG  . PRO A 1 130 ? 17.773  -29.456 36.151  1.000 110.176 0 130 PRO HHH CG  1 ? 
ATOM   978  C CD  . PRO A 1 130 ? 16.431  -29.452 36.852  1.000 107.397 0 130 PRO HHH CD  1 ? 
ATOM   979  N N   . SER A 1 131 ? 17.982  -33.616 35.736  1.000 133.750 0 131 SER HHH N   1 ? 
ATOM   980  C CA  . SER A 1 131 ? 18.890  -34.654 36.303  1.000 140.422 0 131 SER HHH CA  1 ? 
ATOM   981  C C   . SER A 1 131 ? 19.761  -35.246 35.181  1.000 142.390 0 131 SER HHH C   1 ? 
ATOM   982  O O   . SER A 1 131 ? 19.208  -35.965 34.322  1.000 140.004 0 131 SER HHH O   1 ? 
ATOM   983  C CB  . SER A 1 131 ? 18.103  -35.727 37.040  1.000 136.269 0 131 SER HHH CB  1 ? 
ATOM   984  O OG  . SER A 1 131 ? 18.907  -36.400 38.004  1.000 125.055 0 131 SER HHH OG  1 ? 
ATOM   985  N N   . SER A 1 132 ? 21.066  -34.939 35.181  1.000 144.664 0 132 SER HHH N   1 ? 
ATOM   986  C CA  . SER A 1 132 ? 22.062  -35.380 34.165  1.000 136.517 0 132 SER HHH CA  1 ? 
ATOM   987  C C   . SER A 1 132 ? 23.023  -36.404 34.781  1.000 125.992 0 132 SER HHH C   1 ? 
ATOM   988  O O   . SER A 1 132 ? 22.710  -37.604 34.677  1.000 98.415  0 132 SER HHH O   1 ? 
ATOM   989  C CB  . SER A 1 132 ? 22.813  -34.203 33.588  1.000 131.541 0 132 SER HHH CB  1 ? 
ATOM   990  O OG  . SER A 1 132 ? 22.302  -33.847 32.313  1.000 131.580 0 132 SER HHH OG  1 ? 
ATOM   991  N N   . THR A 1 139 ? 24.900  -29.223 28.833  1.000 94.537  0 139 THR HHH N   1 ? 
ATOM   992  C CA  . THR A 1 139 ? 23.726  -28.341 29.088  1.000 99.590  0 139 THR HHH CA  1 ? 
ATOM   993  C C   . THR A 1 139 ? 22.493  -29.167 29.488  1.000 100.250 0 139 THR HHH C   1 ? 
ATOM   994  O O   . THR A 1 139 ? 22.263  -30.262 28.917  1.000 93.533  0 139 THR HHH O   1 ? 
ATOM   995  C CB  . THR A 1 139 ? 23.388  -27.427 27.898  1.000 100.103 0 139 THR HHH CB  1 ? 
ATOM   996  O OG1 . THR A 1 139 ? 22.294  -26.622 28.335  1.000 93.546  0 139 THR HHH OG1 1 ? 
ATOM   997  C CG2 . THR A 1 139 ? 23.013  -28.155 26.623  1.000 101.600 0 139 THR HHH CG2 1 ? 
ATOM   998  N N   . ALA A 1 140 ? 21.716  -28.626 30.426  1.000 104.345 0 140 ALA HHH N   1 ? 
ATOM   999  C CA  . ALA A 1 140 ? 20.465  -29.216 30.948  1.000 103.691 0 140 ALA HHH CA  1 ? 
ATOM   1000 C C   . ALA A 1 140 ? 19.310  -28.221 30.773  1.000 98.388  0 140 ALA HHH C   1 ? 
ATOM   1001 O O   . ALA A 1 140 ? 19.551  -26.997 30.687  1.000 87.287  0 140 ALA HHH O   1 ? 
ATOM   1002 C CB  . ALA A 1 140 ? 20.655  -29.614 32.390  1.000 106.934 0 140 ALA HHH CB  1 ? 
ATOM   1003 N N   . ALA A 1 141 ? 18.093  -28.756 30.702  1.000 97.303  0 141 ALA HHH N   1 ? 
ATOM   1004 C CA  . ALA A 1 141 ? 16.830  -28.004 30.553  1.000 88.978  0 141 ALA HHH CA  1 ? 
ATOM   1005 C C   . ALA A 1 141 ? 16.026  -28.148 31.841  1.000 83.060  0 141 ALA HHH C   1 ? 
ATOM   1006 O O   . ALA A 1 141 ? 16.002  -29.256 32.422  1.000 86.650  0 141 ALA HHH O   1 ? 
ATOM   1007 C CB  . ALA A 1 141 ? 16.052  -28.512 29.363  1.000 87.120  0 141 ALA HHH CB  1 ? 
ATOM   1008 N N   . LEU A 1 142 ? 15.407  -27.057 32.269  1.000 79.010  0 142 LEU HHH N   1 ? 
ATOM   1009 C CA  . LEU A 1 142 ? 14.472  -27.048 33.416  1.000 84.142  0 142 LEU HHH CA  1 ? 
ATOM   1010 C C   . LEU A 1 142 ? 13.327  -26.104 33.074  1.000 77.969  0 142 LEU HHH C   1 ? 
ATOM   1011 O O   . LEU A 1 142 ? 13.430  -25.347 32.089  1.000 78.175  0 142 LEU HHH O   1 ? 
ATOM   1012 C CB  . LEU A 1 142 ? 15.199  -26.633 34.704  1.000 88.557  0 142 LEU HHH CB  1 ? 
ATOM   1013 C CG  . LEU A 1 142 ? 16.101  -25.397 34.625  1.000 87.570  0 142 LEU HHH CG  1 ? 
ATOM   1014 C CD1 . LEU A 1 142 ? 15.392  -24.145 35.120  1.000 90.045  0 142 LEU HHH CD1 1 ? 
ATOM   1015 C CD2 . LEU A 1 142 ? 17.368  -25.613 35.430  1.000 84.072  0 142 LEU HHH CD2 1 ? 
ATOM   1016 N N   . GLY A 1 143 ? 12.275  -26.160 33.870  1.000 69.156  0 143 GLY HHH N   1 ? 
ATOM   1017 C CA  . GLY A 1 143 ? 11.040  -25.441 33.561  1.000 63.658  0 143 GLY HHH CA  1 ? 
ATOM   1018 C C   . GLY A 1 143 ? 10.078  -25.540 34.708  1.000 62.338  0 143 GLY HHH C   1 ? 
ATOM   1019 O O   . GLY A 1 143 ? 10.394  -26.168 35.721  1.000 55.978  0 143 GLY HHH O   1 ? 
ATOM   1020 N N   . CYS A 1 144 ? 8.946   -24.887 34.552  1.000 73.180  0 144 CYS HHH N   1 ? 
ATOM   1021 C CA  . CYS A 1 144 ? 7.759   -25.121 35.385  1.000 79.136  0 144 CYS HHH CA  1 ? 
ATOM   1022 C C   . CYS A 1 144 ? 6.584   -25.345 34.443  1.000 72.945  0 144 CYS HHH C   1 ? 
ATOM   1023 O O   . CYS A 1 144 ? 6.574   -24.824 33.329  1.000 71.988  0 144 CYS HHH O   1 ? 
ATOM   1024 C CB  . CYS A 1 144 ? 7.517   -23.999 36.385  1.000 88.359  0 144 CYS HHH CB  1 ? 
ATOM   1025 S SG  . CYS A 1 144 ? 7.615   -22.335 35.684  1.000 101.984 0 144 CYS HHH SG  1 ? 
ATOM   1026 N N   . LEU A 1 145 ? 5.671   -26.183 34.887  1.000 76.173  0 145 LEU HHH N   1 ? 
ATOM   1027 C CA  . LEU A 1 145 ? 4.437   -26.518 34.168  1.000 77.956  0 145 LEU HHH CA  1 ? 
ATOM   1028 C C   . LEU A 1 145 ? 3.319   -25.751 34.845  1.000 73.968  0 145 LEU HHH C   1 ? 
ATOM   1029 O O   . LEU A 1 145 ? 2.982   -26.139 35.961  1.000 74.892  0 145 LEU HHH O   1 ? 
ATOM   1030 C CB  . LEU A 1 145 ? 4.223   -28.024 34.295  1.000 77.839  0 145 LEU HHH CB  1 ? 
ATOM   1031 C CG  . LEU A 1 145 ? 2.865   -28.529 33.828  1.000 78.739  0 145 LEU HHH CG  1 ? 
ATOM   1032 C CD1 . LEU A 1 145 ? 2.857   -28.756 32.324  1.000 84.558  0 145 LEU HHH CD1 1 ? 
ATOM   1033 C CD2 . LEU A 1 145 ? 2.524   -29.809 34.560  1.000 78.945  0 145 LEU HHH CD2 1 ? 
ATOM   1034 N N   . VAL A 1 146 ? 2.804   -24.713 34.191  1.000 75.062  0 146 VAL HHH N   1 ? 
ATOM   1035 C CA  . VAL A 1 146 ? 1.548   -24.018 34.589  1.000 77.387  0 146 VAL HHH CA  1 ? 
ATOM   1036 C C   . VAL A 1 146 ? 0.379   -24.946 34.283  1.000 78.376  0 146 VAL HHH C   1 ? 
ATOM   1037 O O   . VAL A 1 146 ? 0.344   -25.528 33.186  1.000 97.950  0 146 VAL HHH O   1 ? 
ATOM   1038 C CB  . VAL A 1 146 ? 1.405   -22.694 33.832  1.000 80.204  0 146 VAL HHH CB  1 ? 
ATOM   1039 C CG1 . VAL A 1 146 ? -0.051  -22.316 33.640  1.000 84.995  0 146 VAL HHH CG1 1 ? 
ATOM   1040 C CG2 . VAL A 1 146 ? 2.183   -21.601 34.528  1.000 80.394  0 146 VAL HHH CG2 1 ? 
ATOM   1041 N N   . LYS A 1 147 ? -0.552  -25.105 35.206  1.000 78.479  0 147 LYS HHH N   1 ? 
ATOM   1042 C CA  . LYS A 1 147 ? -1.601  -26.122 34.993  1.000 82.175  0 147 LYS HHH CA  1 ? 
ATOM   1043 C C   . LYS A 1 147 ? -2.928  -25.616 35.550  1.000 78.095  0 147 LYS HHH C   1 ? 
ATOM   1044 O O   . LYS A 1 147 ? -2.930  -25.022 36.616  1.000 78.347  0 147 LYS HHH O   1 ? 
ATOM   1045 C CB  . LYS A 1 147 ? -1.169  -27.453 35.607  1.000 81.623  0 147 LYS HHH CB  1 ? 
ATOM   1046 C CG  . LYS A 1 147 ? -2.101  -28.587 35.247  1.000 92.750  0 147 LYS HHH CG  1 ? 
ATOM   1047 C CD  . LYS A 1 147 ? -1.672  -29.929 35.753  1.000 102.885 0 147 LYS HHH CD  1 ? 
ATOM   1048 C CE  . LYS A 1 147 ? -2.743  -30.958 35.458  1.000 113.129 0 147 LYS HHH CE  1 ? 
ATOM   1049 N NZ  . LYS A 1 147 ? -2.610  -32.181 36.282  1.000 125.733 0 147 LYS HHH NZ  1 ? 
ATOM   1050 N N   . ASP A 1 148 ? -4.015  -25.899 34.844  1.000 75.274  0 148 ASP HHH N   1 ? 
ATOM   1051 C CA  . ASP A 1 148 ? -5.397  -25.639 35.311  1.000 75.743  0 148 ASP HHH CA  1 ? 
ATOM   1052 C C   . ASP A 1 148 ? -5.588  -24.134 35.511  1.000 72.256  0 148 ASP HHH C   1 ? 
ATOM   1053 O O   . ASP A 1 148 ? -5.751  -23.691 36.649  1.000 75.894  0 148 ASP HHH O   1 ? 
ATOM   1054 C CB  . ASP A 1 148 ? -5.705  -26.476 36.557  1.000 79.107  0 148 ASP HHH CB  1 ? 
ATOM   1055 C CG  . ASP A 1 148 ? -5.672  -27.973 36.288  1.000 85.230  0 148 ASP HHH CG  1 ? 
ATOM   1056 O OD1 . ASP A 1 148 ? -5.985  -28.379 35.143  1.000 96.423  0 148 ASP HHH OD1 1 ? 
ATOM   1057 O OD2 . ASP A 1 148 ? -5.315  -28.719 37.217  1.000 90.743  0 148 ASP HHH OD2 1 ? 
ATOM   1058 N N   . TYR A 1 149 ? -5.627  -23.365 34.431  1.000 75.245  0 149 TYR HHH N   1 ? 
ATOM   1059 C CA  . TYR A 1 149 ? -5.893  -21.910 34.532  1.000 77.409  0 149 TYR HHH CA  1 ? 
ATOM   1060 C C   . TYR A 1 149 ? -7.032  -21.498 33.601  1.000 73.104  0 149 TYR HHH C   1 ? 
ATOM   1061 O O   . TYR A 1 149 ? -7.265  -22.106 32.549  1.000 73.858  0 149 TYR HHH O   1 ? 
ATOM   1062 C CB  . TYR A 1 149 ? -4.605  -21.116 34.319  1.000 83.180  0 149 TYR HHH CB  1 ? 
ATOM   1063 C CG  . TYR A 1 149 ? -4.143  -20.873 32.906  1.000 86.590  0 149 TYR HHH CG  1 ? 
ATOM   1064 C CD1 . TYR A 1 149 ? -4.687  -19.842 32.157  1.000 97.772  0 149 TYR HHH CD1 1 ? 
ATOM   1065 C CD2 . TYR A 1 149 ? -3.104  -21.608 32.352  1.000 84.273  0 149 TYR HHH CD2 1 ? 
ATOM   1066 C CE1 . TYR A 1 149 ? -4.251  -19.583 30.866  1.000 111.141 0 149 TYR HHH CE1 1 ? 
ATOM   1067 C CE2 . TYR A 1 149 ? -2.633  -21.343 31.075  1.000 87.962  0 149 TYR HHH CE2 1 ? 
ATOM   1068 C CZ  . TYR A 1 149 ? -3.206  -20.328 30.329  1.000 105.114 0 149 TYR HHH CZ  1 ? 
ATOM   1069 O OH  . TYR A 1 149 ? -2.736  -20.068 29.069  1.000 114.342 0 149 TYR HHH OH  1 ? 
ATOM   1070 N N   . PHE A 1 150 ? -7.735  -20.449 33.995  1.000 69.616  0 150 PHE HHH N   1 ? 
ATOM   1071 C CA  . PHE A 1 150 ? -8.830  -19.881 33.183  1.000 74.121  0 150 PHE HHH CA  1 ? 
ATOM   1072 C C   . PHE A 1 150 ? -8.983  -18.405 33.507  1.000 73.966  0 150 PHE HHH C   1 ? 
ATOM   1073 O O   . PHE A 1 150 ? -8.860  -18.025 34.666  1.000 70.437  0 150 PHE HHH O   1 ? 
ATOM   1074 C CB  . PHE A 1 150 ? -10.135 -20.632 33.426  1.000 80.490  0 150 PHE HHH CB  1 ? 
ATOM   1075 C CG  . PHE A 1 150 ? -11.082 -20.552 32.259  1.000 89.435  0 150 PHE HHH CG  1 ? 
ATOM   1076 C CD1 . PHE A 1 150 ? -10.868 -21.336 31.135  1.000 96.947  0 150 PHE HHH CD1 1 ? 
ATOM   1077 C CD2 . PHE A 1 150 ? -12.168 -19.689 32.272  1.000 96.214  0 150 PHE HHH CD2 1 ? 
ATOM   1078 C CE1 . PHE A 1 150 ? -11.734 -21.272 30.053  1.000 100.998 0 150 PHE HHH CE1 1 ? 
ATOM   1079 C CE2 . PHE A 1 150 ? -13.026 -19.617 31.185  1.000 103.266 0 150 PHE HHH CE2 1 ? 
ATOM   1080 C CZ  . PHE A 1 150 ? -12.811 -20.413 30.081  1.000 103.406 0 150 PHE HHH CZ  1 ? 
ATOM   1081 N N   . PRO A 1 151 ? -9.172  -17.527 32.493  1.000 79.204  0 151 PRO HHH N   1 ? 
ATOM   1082 C CA  . PRO A 1 151 ? -8.951  -17.858 31.083  1.000 81.306  0 151 PRO HHH CA  1 ? 
ATOM   1083 C C   . PRO A 1 151 ? -7.514  -17.528 30.638  1.000 78.644  0 151 PRO HHH C   1 ? 
ATOM   1084 O O   . PRO A 1 151 ? -6.678  -17.334 31.482  1.000 76.668  0 151 PRO HHH O   1 ? 
ATOM   1085 C CB  . PRO A 1 151 ? -9.962  -16.912 30.425  1.000 84.766  0 151 PRO HHH CB  1 ? 
ATOM   1086 C CG  . PRO A 1 151 ? -9.802  -15.643 31.232  1.000 82.500  0 151 PRO HHH CG  1 ? 
ATOM   1087 C CD  . PRO A 1 151 ? -9.622  -16.136 32.654  1.000 81.331  0 151 PRO HHH CD  1 ? 
ATOM   1088 N N   . GLU A 1 152 ? -7.267  -17.430 29.331  1.000 79.913  0 152 GLU HHH N   1 ? 
ATOM   1089 C CA  . GLU A 1 152 ? -6.009  -16.851 28.799  1.000 81.676  0 152 GLU HHH CA  1 ? 
ATOM   1090 C C   . GLU A 1 152 ? -6.029  -15.348 29.051  1.000 81.343  0 152 GLU HHH C   1 ? 
ATOM   1091 O O   . GLU A 1 152 ? -7.092  -14.751 29.201  1.000 73.829  0 152 GLU HHH O   1 ? 
ATOM   1092 C CB  . GLU A 1 152 ? -5.848  -17.149 27.314  1.000 92.203  0 152 GLU HHH CB  1 ? 
ATOM   1093 C CG  . GLU A 1 152 ? -5.292  -18.535 27.039  1.000 104.888 0 152 GLU HHH CG  1 ? 
ATOM   1094 C CD  . GLU A 1 152 ? -5.669  -19.074 25.669  1.000 112.848 0 152 GLU HHH CD  1 ? 
ATOM   1095 O OE1 . GLU A 1 152 ? -6.370  -18.363 24.923  1.000 127.714 0 152 GLU HHH OE1 1 ? 
ATOM   1096 O OE2 . GLU A 1 152 ? -5.270  -20.202 25.352  1.000 119.150 0 152 GLU HHH OE2 1 ? 
ATOM   1097 N N   . PRO A 1 153 ? -4.855  -14.684 29.137  1.000 85.378  0 153 PRO HHH N   1 ? 
ATOM   1098 C CA  . PRO A 1 153 ? -3.551  -15.351 29.150  1.000 82.753  0 153 PRO HHH CA  1 ? 
ATOM   1099 C C   . PRO A 1 153 ? -2.818  -15.474 30.498  1.000 78.284  0 153 PRO HHH C   1 ? 
ATOM   1100 O O   . PRO A 1 153 ? -3.145  -14.792 31.434  1.000 65.815  0 153 PRO HHH O   1 ? 
ATOM   1101 C CB  . PRO A 1 153 ? -2.765  -14.368 28.273  1.000 85.233  0 153 PRO HHH CB  1 ? 
ATOM   1102 C CG  . PRO A 1 153 ? -3.274  -12.998 28.704  1.000 88.528  0 153 PRO HHH CG  1 ? 
ATOM   1103 C CD  . PRO A 1 153 ? -4.719  -13.218 29.113  1.000 89.015  0 153 PRO HHH CD  1 ? 
ATOM   1104 N N   . VAL A 1 154 ? -1.793  -16.323 30.531  1.000 89.613  0 154 VAL HHH N   1 ? 
ATOM   1105 C CA  . VAL A 1 154 ? -0.734  -16.329 31.582  1.000 91.680  0 154 VAL HHH CA  1 ? 
ATOM   1106 C C   . VAL A 1 154 ? 0.567   -15.888 30.913  1.000 87.875  0 154 VAL HHH C   1 ? 
ATOM   1107 O O   . VAL A 1 154 ? 0.805   -16.314 29.780  1.000 99.081  0 154 VAL HHH O   1 ? 
ATOM   1108 C CB  . VAL A 1 154 ? -0.606  -17.717 32.238  1.000 92.439  0 154 VAL HHH CB  1 ? 
ATOM   1109 C CG1 . VAL A 1 154 ? 0.559   -17.798 33.204  1.000 102.324 0 154 VAL HHH CG1 1 ? 
ATOM   1110 C CG2 . VAL A 1 154 ? -1.888  -18.105 32.955  1.000 101.624 0 154 VAL HHH CG2 1 ? 
ATOM   1111 N N   . THR A 1 155 ? 1.368   -15.063 31.585  1.000 88.611  0 155 THR HHH N   1 ? 
ATOM   1112 C CA  . THR A 1 155 ? 2.740   -14.692 31.145  1.000 87.147  0 155 THR HHH CA  1 ? 
ATOM   1113 C C   . THR A 1 155 ? 3.749   -15.295 32.130  1.000 81.507  0 155 THR HHH C   1 ? 
ATOM   1114 O O   . THR A 1 155 ? 3.480   -15.288 33.342  1.000 77.271  0 155 THR HHH O   1 ? 
ATOM   1115 C CB  . THR A 1 155 ? 2.881   -13.172 31.013  1.000 86.501  0 155 THR HHH CB  1 ? 
ATOM   1116 O OG1 . THR A 1 155 ? 3.406   -12.675 32.244  1.000 83.528  0 155 THR HHH OG1 1 ? 
ATOM   1117 C CG2 . THR A 1 155 ? 1.569   -12.492 30.679  1.000 90.610  0 155 THR HHH CG2 1 ? 
ATOM   1118 N N   . VAL A 1 156 ? 4.873   -15.800 31.629  1.000 84.010  0 156 VAL HHH N   1 ? 
ATOM   1119 C CA  . VAL A 1 156 ? 5.903   -16.464 32.477  1.000 84.696  0 156 VAL HHH CA  1 ? 
ATOM   1120 C C   . VAL A 1 156 ? 7.262   -15.804 32.247  1.000 86.437  0 156 VAL HHH C   1 ? 
ATOM   1121 O O   . VAL A 1 156 ? 7.769   -15.860 31.113  1.000 89.983  0 156 VAL HHH O   1 ? 
ATOM   1122 C CB  . VAL A 1 156 ? 5.972   -17.975 32.212  1.000 81.381  0 156 VAL HHH CB  1 ? 
ATOM   1123 C CG1 . VAL A 1 156 ? 6.960   -18.656 33.146  1.000 80.759  0 156 VAL HHH CG1 1 ? 
ATOM   1124 C CG2 . VAL A 1 156 ? 4.597   -18.607 32.314  1.000 83.232  0 156 VAL HHH CG2 1 ? 
ATOM   1125 N N   . SER A 1 157 ? 7.822   -15.227 33.310  1.000 83.366  0 157 SER HHH N   1 ? 
ATOM   1126 C CA  . SER A 1 157 ? 9.227   -14.767 33.388  1.000 77.031  0 157 SER HHH CA  1 ? 
ATOM   1127 C C   . SER A 1 157 ? 10.050  -15.822 34.133  1.000 70.455  0 157 SER HHH C   1 ? 
ATOM   1128 O O   . SER A 1 157 ? 9.453   -16.740 34.715  1.000 69.824  0 157 SER HHH O   1 ? 
ATOM   1129 C CB  . SER A 1 157 ? 9.306   -13.410 34.038  1.000 78.284  0 157 SER HHH CB  1 ? 
ATOM   1130 O OG  . SER A 1 157 ? 8.452   -13.340 35.167  1.000 72.806  0 157 SER HHH OG  1 ? 
ATOM   1131 N N   . TRP A 1 158 ? 11.374  -15.697 34.081  1.000 68.543  0 158 TRP HHH N   1 ? 
ATOM   1132 C CA  . TRP A 1 158 ? 12.337  -16.562 34.802  1.000 67.511  0 158 TRP HHH CA  1 ? 
ATOM   1133 C C   . TRP A 1 158 ? 13.289  -15.688 35.622  1.000 68.668  0 158 TRP HHH C   1 ? 
ATOM   1134 O O   . TRP A 1 158 ? 13.767  -14.684 35.075  1.000 68.552  0 158 TRP HHH O   1 ? 
ATOM   1135 C CB  . TRP A 1 158 ? 13.064  -17.449 33.791  1.000 68.499  0 158 TRP HHH CB  1 ? 
ATOM   1136 C CG  . TRP A 1 158 ? 12.282  -18.673 33.431  1.000 64.575  0 158 TRP HHH CG  1 ? 
ATOM   1137 C CD1 . TRP A 1 158 ? 11.441  -18.851 32.374  1.000 62.953  0 158 TRP HHH CD1 1 ? 
ATOM   1138 C CD2 . TRP A 1 158 ? 12.268  -19.907 34.162  1.000 69.843  0 158 TRP HHH CD2 1 ? 
ATOM   1139 N NE1 . TRP A 1 158 ? 10.916  -20.115 32.395  1.000 65.287  0 158 TRP HHH NE1 1 ? 
ATOM   1140 C CE2 . TRP A 1 158 ? 11.401  -20.790 33.480  1.000 69.106  0 158 TRP HHH CE2 1 ? 
ATOM   1141 C CE3 . TRP A 1 158 ? 12.910  -20.355 35.322  1.000 73.821  0 158 TRP HHH CE3 1 ? 
ATOM   1142 C CZ2 . TRP A 1 158 ? 11.152  -22.089 33.928  1.000 63.263  0 158 TRP HHH CZ2 1 ? 
ATOM   1143 C CZ3 . TRP A 1 158 ? 12.667  -21.641 35.760  1.000 73.967  0 158 TRP HHH CZ3 1 ? 
ATOM   1144 C CH2 . TRP A 1 158 ? 11.798  -22.492 35.074  1.000 66.893  0 158 TRP HHH CH2 1 ? 
ATOM   1145 N N   . ASN A 1 159 ? 13.538  -16.046 36.884  1.000 71.857  0 159 ASN HHH N   1 ? 
ATOM   1146 C CA  . ASN A 1 159 ? 14.416  -15.273 37.800  1.000 76.421  0 159 ASN HHH CA  1 ? 
ATOM   1147 C C   . ASN A 1 159 ? 14.049  -13.794 37.707  1.000 86.760  0 159 ASN HHH C   1 ? 
ATOM   1148 O O   . ASN A 1 159 ? 14.958  -12.955 37.560  1.000 84.422  0 159 ASN HHH O   1 ? 
ATOM   1149 C CB  . ASN A 1 159 ? 15.890  -15.450 37.461  1.000 77.636  0 159 ASN HHH CB  1 ? 
ATOM   1150 C CG  . ASN A 1 159 ? 16.398  -16.816 37.843  1.000 80.993  0 159 ASN HHH CG  1 ? 
ATOM   1151 O OD1 . ASN A 1 159 ? 15.839  -17.453 38.726  1.000 92.523  0 159 ASN HHH OD1 1 ? 
ATOM   1152 N ND2 . ASN A 1 159 ? 17.455  -17.264 37.189  1.000 84.216  0 159 ASN HHH ND2 1 ? 
ATOM   1153 N N   . SER A 1 160 ? 12.750  -13.505 37.760  1.000 99.350  0 160 SER HHH N   1 ? 
ATOM   1154 C CA  . SER A 1 160 ? 12.183  -12.132 37.817  1.000 98.119  0 160 SER HHH CA  1 ? 
ATOM   1155 C C   . SER A 1 160 ? 12.509  -11.387 36.517  1.000 96.325  0 160 SER HHH C   1 ? 
ATOM   1156 O O   . SER A 1 160 ? 12.703  -10.167 36.579  1.000 91.144  0 160 SER HHH O   1 ? 
ATOM   1157 C CB  . SER A 1 160 ? 12.685  -11.394 39.039  1.000 96.477  0 160 SER HHH CB  1 ? 
ATOM   1158 O OG  . SER A 1 160 ? 12.647  -12.224 40.195  1.000 93.902  0 160 SER HHH OG  1 ? 
ATOM   1159 N N   . GLY A 1 161 ? 12.562  -12.109 35.391  1.000 88.681  0 161 GLY HHH N   1 ? 
ATOM   1160 C CA  . GLY A 1 161 ? 12.856  -11.557 34.056  1.000 85.766  0 161 GLY HHH CA  1 ? 
ATOM   1161 C C   . GLY A 1 161 ? 14.345  -11.356 33.819  1.000 84.066  0 161 GLY HHH C   1 ? 
ATOM   1162 O O   . GLY A 1 161 ? 14.699  -10.961 32.698  1.000 86.114  0 161 GLY HHH O   1 ? 
ATOM   1163 N N   . ALA A 1 162 ? 15.197  -11.618 34.816  1.000 84.561  0 162 ALA HHH N   1 ? 
ATOM   1164 C CA  . ALA A 1 162 ? 16.673  -11.511 34.696  1.000 90.420  0 162 ALA HHH CA  1 ? 
ATOM   1165 C C   . ALA A 1 162 ? 17.170  -12.481 33.619  1.000 91.263  0 162 ALA HHH C   1 ? 
ATOM   1166 O O   . ALA A 1 162 ? 18.011  -12.071 32.796  1.000 99.556  0 162 ALA HHH O   1 ? 
ATOM   1167 C CB  . ALA A 1 162 ? 17.344  -11.786 36.023  1.000 89.801  0 162 ALA HHH CB  1 ? 
ATOM   1168 N N   . LEU A 1 163 ? 16.667  -13.718 33.642  1.000 82.645  0 163 LEU HHH N   1 ? 
ATOM   1169 C CA  . LEU A 1 163 ? 17.012  -14.797 32.682  1.000 80.681  0 163 LEU HHH CA  1 ? 
ATOM   1170 C C   . LEU A 1 163 ? 16.004  -14.794 31.523  1.000 80.153  0 163 LEU HHH C   1 ? 
ATOM   1171 O O   . LEU A 1 163 ? 14.797  -14.800 31.806  1.000 81.729  0 163 LEU HHH O   1 ? 
ATOM   1172 C CB  . LEU A 1 163 ? 16.990  -16.119 33.448  1.000 78.893  0 163 LEU HHH CB  1 ? 
ATOM   1173 C CG  . LEU A 1 163 ? 17.142  -17.375 32.599  1.000 78.630  0 163 LEU HHH CG  1 ? 
ATOM   1174 C CD1 . LEU A 1 163 ? 18.524  -17.445 31.975  1.000 81.437  0 163 LEU HHH CD1 1 ? 
ATOM   1175 C CD2 . LEU A 1 163 ? 16.875  -18.606 33.442  1.000 83.767  0 163 LEU HHH CD2 1 ? 
ATOM   1176 N N   . THR A 1 164 ? 16.482  -14.798 30.272  1.000 84.140  0 164 THR HHH N   1 ? 
ATOM   1177 C CA  . THR A 1 164 ? 15.638  -14.680 29.046  1.000 88.091  0 164 THR HHH CA  1 ? 
ATOM   1178 C C   . THR A 1 164 ? 16.113  -15.598 27.908  1.000 88.812  0 164 THR HHH C   1 ? 
ATOM   1179 O O   . THR A 1 164 ? 15.269  -15.934 27.051  1.000 97.100  0 164 THR HHH O   1 ? 
ATOM   1180 C CB  . THR A 1 164 ? 15.586  -13.234 28.535  1.000 87.625  0 164 THR HHH CB  1 ? 
ATOM   1181 O OG1 . THR A 1 164 ? 16.930  -12.756 28.470  1.000 94.393  0 164 THR HHH OG1 1 ? 
ATOM   1182 C CG2 . THR A 1 164 ? 14.736  -12.327 29.399  1.000 81.863  0 164 THR HHH CG2 1 ? 
ATOM   1183 N N   . SER A 1 165 ? 17.392  -15.976 27.858  1.000 81.575  0 165 SER HHH N   1 ? 
ATOM   1184 C CA  . SER A 1 165 ? 17.929  -16.876 26.805  1.000 85.839  0 165 SER HHH CA  1 ? 
ATOM   1185 C C   . SER A 1 165 ? 17.690  -18.346 27.189  1.000 84.577  0 165 SER HHH C   1 ? 
ATOM   1186 O O   . SER A 1 165 ? 17.785  -18.674 28.388  1.000 75.748  0 165 SER HHH O   1 ? 
ATOM   1187 C CB  . SER A 1 165 ? 19.381  -16.591 26.544  1.000 91.050  0 165 SER HHH CB  1 ? 
ATOM   1188 O OG  . SER A 1 165 ? 20.197  -17.120 27.573  1.000 95.450  0 165 SER HHH OG  1 ? 
ATOM   1189 N N   . GLY A 1 166 ? 17.390  -19.193 26.197  1.000 83.473  0 166 GLY HHH N   1 ? 
ATOM   1190 C CA  . GLY A 1 166 ? 17.074  -20.624 26.378  1.000 84.128  0 166 GLY HHH CA  1 ? 
ATOM   1191 C C   . GLY A 1 166 ? 15.602  -20.855 26.685  1.000 88.014  0 166 GLY HHH C   1 ? 
ATOM   1192 O O   . GLY A 1 166 ? 15.180  -22.026 26.617  1.000 105.737 0 166 GLY HHH O   1 ? 
ATOM   1193 N N   . VAL A 1 167 ? 14.842  -19.788 26.980  1.000 84.420  0 167 VAL HHH N   1 ? 
ATOM   1194 C CA  . VAL A 1 167 ? 13.450  -19.830 27.534  1.000 73.672  0 167 VAL HHH CA  1 ? 
ATOM   1195 C C   . VAL A 1 167 ? 12.435  -20.056 26.415  1.000 73.052  0 167 VAL HHH C   1 ? 
ATOM   1196 O O   . VAL A 1 167 ? 12.321  -19.192 25.533  1.000 74.275  0 167 VAL HHH O   1 ? 
ATOM   1197 C CB  . VAL A 1 167 ? 13.103  -18.537 28.288  1.000 74.778  0 167 VAL HHH CB  1 ? 
ATOM   1198 C CG1 . VAL A 1 167 ? 11.657  -18.535 28.765  1.000 74.289  0 167 VAL HHH CG1 1 ? 
ATOM   1199 C CG2 . VAL A 1 167 ? 14.059  -18.309 29.447  1.000 80.787  0 167 VAL HHH CG2 1 ? 
ATOM   1200 N N   . HIS A 1 168 ? 11.682  -21.150 26.494  1.000 77.115  0 168 HIS HHH N   1 ? 
ATOM   1201 C CA  . HIS A 1 168 ? 10.577  -21.477 25.556  1.000 79.548  0 168 HIS HHH CA  1 ? 
ATOM   1202 C C   . HIS A 1 168 ? 9.273   -21.565 26.362  1.000 78.555  0 168 HIS HHH C   1 ? 
ATOM   1203 O O   . HIS A 1 168 ? 8.901   -22.664 26.790  1.000 83.579  0 168 HIS HHH O   1 ? 
ATOM   1204 C CB  . HIS A 1 168 ? 10.921  -22.742 24.739  1.000 85.265  0 168 HIS HHH CB  1 ? 
ATOM   1205 C CG  . HIS A 1 168 ? 11.980  -22.551 23.696  1.000 84.158  0 168 HIS HHH CG  1 ? 
ATOM   1206 N ND1 . HIS A 1 168 ? 11.684  -22.193 22.392  1.000 84.018  0 168 HIS HHH ND1 1 ? 
ATOM   1207 C CD2 . HIS A 1 168 ? 13.327  -22.673 23.750  1.000 81.991  0 168 HIS HHH CD2 1 ? 
ATOM   1208 C CE1 . HIS A 1 168 ? 12.800  -22.100 21.694  1.000 82.490  0 168 HIS HHH CE1 1 ? 
ATOM   1209 N NE2 . HIS A 1 168 ? 13.820  -22.389 22.504  1.000 82.202  0 168 HIS HHH NE2 1 ? 
ATOM   1210 N N   . THR A 1 169 ? 8.607   -20.433 26.586  1.000 80.876  0 169 THR HHH N   1 ? 
ATOM   1211 C CA  . THR A 1 169 ? 7.205   -20.383 27.077  1.000 83.373  0 169 THR HHH CA  1 ? 
ATOM   1212 C C   . THR A 1 169 ? 6.297   -20.815 25.916  1.000 84.405  0 169 THR HHH C   1 ? 
ATOM   1213 O O   . THR A 1 169 ? 6.156   -20.025 24.960  1.000 95.706  0 169 THR HHH O   1 ? 
ATOM   1214 C CB  . THR A 1 169 ? 6.865   -18.994 27.638  1.000 85.600  0 169 THR HHH CB  1 ? 
ATOM   1215 O OG1 . THR A 1 169 ? 7.868   -18.613 28.584  1.000 77.459  0 169 THR HHH OG1 1 ? 
ATOM   1216 C CG2 . THR A 1 169 ? 5.503   -18.950 28.294  1.000 85.234  0 169 THR HHH CG2 1 ? 
ATOM   1217 N N   . PHE A 1 170 ? 5.746   -22.033 25.985  1.000 76.062  0 170 PHE HHH N   1 ? 
ATOM   1218 C CA  . PHE A 1 170 ? 4.945   -22.696 24.918  1.000 74.819  0 170 PHE HHH CA  1 ? 
ATOM   1219 C C   . PHE A 1 170 ? 3.537   -22.108 24.829  1.000 77.039  0 170 PHE HHH C   1 ? 
ATOM   1220 O O   . PHE A 1 170 ? 3.034   -21.540 25.789  1.000 84.813  0 170 PHE HHH O   1 ? 
ATOM   1221 C CB  . PHE A 1 170 ? 4.842   -24.201 25.185  1.000 69.318  0 170 PHE HHH CB  1 ? 
ATOM   1222 C CG  . PHE A 1 170 ? 6.104   -24.961 24.898  1.000 61.376  0 170 PHE HHH CG  1 ? 
ATOM   1223 C CD1 . PHE A 1 170 ? 7.075   -25.122 25.863  1.000 65.589  0 170 PHE HHH CD1 1 ? 
ATOM   1224 C CD2 . PHE A 1 170 ? 6.317   -25.516 23.651  1.000 68.531  0 170 PHE HHH CD2 1 ? 
ATOM   1225 C CE1 . PHE A 1 170 ? 8.245   -25.809 25.578  1.000 72.211  0 170 PHE HHH CE1 1 ? 
ATOM   1226 C CE2 . PHE A 1 170 ? 7.485   -26.204 23.367  1.000 69.312  0 170 PHE HHH CE2 1 ? 
ATOM   1227 C CZ  . PHE A 1 170 ? 8.448   -26.348 24.330  1.000 71.352  0 170 PHE HHH CZ  1 ? 
ATOM   1228 N N   . PRO A 1 171 ? 2.846   -22.209 23.670  1.000 80.419  0 171 PRO HHH N   1 ? 
ATOM   1229 C CA  . PRO A 1 171 ? 1.423   -21.879 23.596  1.000 79.699  0 171 PRO HHH CA  1 ? 
ATOM   1230 C C   . PRO A 1 171 ? 0.560   -22.745 24.517  1.000 75.164  0 171 PRO HHH C   1 ? 
ATOM   1231 O O   . PRO A 1 171 ? 0.925   -23.874 24.805  1.000 72.327  0 171 PRO HHH O   1 ? 
ATOM   1232 C CB  . PRO A 1 171 ? 1.032   -22.138 22.137  1.000 77.849  0 171 PRO HHH CB  1 ? 
ATOM   1233 C CG  . PRO A 1 171 ? 2.341   -22.026 21.388  1.000 83.495  0 171 PRO HHH CG  1 ? 
ATOM   1234 C CD  . PRO A 1 171 ? 3.404   -22.527 22.349  1.000 83.075  0 171 PRO HHH CD  1 ? 
ATOM   1235 N N   . ALA A 1 172 ? -0.575  -22.181 24.925  1.000 75.950  0 172 ALA HHH N   1 ? 
ATOM   1236 C CA  . ALA A 1 172 ? -1.525  -22.783 25.884  1.000 80.369  0 172 ALA HHH CA  1 ? 
ATOM   1237 C C   . ALA A 1 172 ? -2.245  -23.958 25.228  1.000 77.109  0 172 ALA HHH C   1 ? 
ATOM   1238 O O   . ALA A 1 172 ? -2.420  -23.933 24.005  1.000 90.803  0 172 ALA HHH O   1 ? 
ATOM   1239 C CB  . ALA A 1 172 ? -2.494  -21.732 26.344  1.000 83.513  0 172 ALA HHH CB  1 ? 
ATOM   1240 N N   . VAL A 1 173 ? -2.669  -24.930 26.030  1.000 77.072  0 173 VAL HHH N   1 ? 
ATOM   1241 C CA  . VAL A 1 173 ? -3.382  -26.151 25.563  1.000 78.987  0 173 VAL HHH CA  1 ? 
ATOM   1242 C C   . VAL A 1 173 ? -4.619  -26.336 26.436  1.000 76.127  0 173 VAL HHH C   1 ? 
ATOM   1243 O O   . VAL A 1 173 ? -4.460  -26.554 27.639  1.000 79.217  0 173 VAL HHH O   1 ? 
ATOM   1244 C CB  . VAL A 1 173 ? -2.452  -27.380 25.607  1.000 87.355  0 173 VAL HHH CB  1 ? 
ATOM   1245 C CG1 . VAL A 1 173 ? -3.210  -28.698 25.464  1.000 88.866  0 173 VAL HHH CG1 1 ? 
ATOM   1246 C CG2 . VAL A 1 173 ? -1.345  -27.266 24.563  1.000 88.221  0 173 VAL HHH CG2 1 ? 
ATOM   1247 N N   . LEU A 1 174 ? -5.804  -26.275 25.832  1.000 88.078  0 174 LEU HHH N   1 ? 
ATOM   1248 C CA  . LEU A 1 174 ? -7.104  -26.550 26.497  1.000 94.665  0 174 LEU HHH CA  1 ? 
ATOM   1249 C C   . LEU A 1 174 ? -7.207  -28.051 26.785  1.000 91.664  0 174 LEU HHH C   1 ? 
ATOM   1250 O O   . LEU A 1 174 ? -6.982  -28.840 25.866  1.000 89.907  0 174 LEU HHH O   1 ? 
ATOM   1251 C CB  . LEU A 1 174 ? -8.234  -26.069 25.579  1.000 101.857 0 174 LEU HHH CB  1 ? 
ATOM   1252 C CG  . LEU A 1 174 ? -9.565  -25.740 26.252  1.000 109.128 0 174 LEU HHH CG  1 ? 
ATOM   1253 C CD1 . LEU A 1 174 ? -10.517 -26.929 26.178  1.000 110.005 0 174 LEU HHH CD1 1 ? 
ATOM   1254 C CD2 . LEU A 1 174 ? -9.365  -25.268 27.692  1.000 116.324 0 174 LEU HHH CD2 1 ? 
ATOM   1255 N N   . GLN A 1 175 ? -7.497  -28.431 28.026  1.000 95.507  0 175 GLN HHH N   1 ? 
ATOM   1256 C CA  . GLN A 1 175 ? -7.698  -29.853 28.410  1.000 102.314 0 175 GLN HHH CA  1 ? 
ATOM   1257 C C   . GLN A 1 175 ? -9.209  -30.102 28.497  1.000 111.319 0 175 GLN HHH C   1 ? 
ATOM   1258 O O   . GLN A 1 175 ? -9.973  -29.101 28.529  1.000 100.424 0 175 GLN HHH O   1 ? 
ATOM   1259 C CB  . GLN A 1 175 ? -7.001  -30.166 29.735  1.000 101.182 0 175 GLN HHH CB  1 ? 
ATOM   1260 C CG  . GLN A 1 175 ? -5.664  -29.464 29.914  1.000 105.984 0 175 GLN HHH CG  1 ? 
ATOM   1261 C CD  . GLN A 1 175 ? -5.326  -29.230 31.368  1.000 120.086 0 175 GLN HHH CD  1 ? 
ATOM   1262 O OE1 . GLN A 1 175 ? -4.288  -29.668 31.855  1.000 125.194 0 175 GLN HHH OE1 1 ? 
ATOM   1263 N NE2 . GLN A 1 175 ? -6.196  -28.526 32.077  1.000 128.896 0 175 GLN HHH NE2 1 ? 
ATOM   1264 N N   . SER A 1 176 ? -9.623  -31.375 28.554  1.000 114.164 0 176 SER HHH N   1 ? 
ATOM   1265 C CA  . SER A 1 176 ? -11.037 -31.808 28.717  1.000 109.471 0 176 SER HHH CA  1 ? 
ATOM   1266 C C   . SER A 1 176 ? -11.714 -30.959 29.801  1.000 104.692 0 176 SER HHH C   1 ? 
ATOM   1267 O O   . SER A 1 176 ? -12.819 -30.438 29.539  1.000 100.191 0 176 SER HHH O   1 ? 
ATOM   1268 C CB  . SER A 1 176 ? -11.122 -33.279 29.041  1.000 107.462 0 176 SER HHH CB  1 ? 
ATOM   1269 O OG  . SER A 1 176 ? -10.506 -33.556 30.288  1.000 100.706 0 176 SER HHH OG  1 ? 
ATOM   1270 N N   . SER A 1 177 ? -11.036 -30.790 30.944  1.000 97.398  0 177 SER HHH N   1 ? 
ATOM   1271 C CA  . SER A 1 177 ? -11.506 -30.049 32.146  1.000 93.775  0 177 SER HHH CA  1 ? 
ATOM   1272 C C   . SER A 1 177 ? -12.059 -28.670 31.761  1.000 90.589  0 177 SER HHH C   1 ? 
ATOM   1273 O O   . SER A 1 177 ? -12.823 -28.101 32.566  1.000 90.431  0 177 SER HHH O   1 ? 
ATOM   1274 C CB  . SER A 1 177 ? -10.405 -29.920 33.162  1.000 89.011  0 177 SER HHH CB  1 ? 
ATOM   1275 O OG  . SER A 1 177 ? -9.313  -29.191 32.625  1.000 95.217  0 177 SER HHH OG  1 ? 
ATOM   1276 N N   . GLY A 1 178 ? -11.688 -28.156 30.586  1.000 89.968  0 178 GLY HHH N   1 ? 
ATOM   1277 C CA  . GLY A 1 178 ? -12.065 -26.808 30.120  1.000 91.109  0 178 GLY HHH CA  1 ? 
ATOM   1278 C C   . GLY A 1 178 ? -11.098 -25.774 30.665  1.000 94.127  0 178 GLY HHH C   1 ? 
ATOM   1279 O O   . GLY A 1 178 ? -11.361 -24.558 30.505  1.000 89.733  0 178 GLY HHH O   1 ? 
ATOM   1280 N N   . LEU A 1 179 ? -10.009 -26.247 31.282  1.000 95.849  0 179 LEU HHH N   1 ? 
ATOM   1281 C CA  . LEU A 1 179 ? -8.916  -25.400 31.828  1.000 93.830  0 179 LEU HHH CA  1 ? 
ATOM   1282 C C   . LEU A 1 179 ? -7.697  -25.464 30.906  1.000 88.764  0 179 LEU HHH C   1 ? 
ATOM   1283 O O   . LEU A 1 179 ? -7.455  -26.531 30.283  1.000 84.202  0 179 LEU HHH O   1 ? 
ATOM   1284 C CB  . LEU A 1 179 ? -8.547  -25.895 33.226  1.000 96.007  0 179 LEU HHH CB  1 ? 
ATOM   1285 C CG  . LEU A 1 179 ? -9.536  -25.536 34.330  1.000 98.501  0 179 LEU HHH CG  1 ? 
ATOM   1286 C CD1 . LEU A 1 179 ? -9.412  -26.542 35.473  1.000 100.507 0 179 LEU HHH CD1 1 ? 
ATOM   1287 C CD2 . LEU A 1 179 ? -9.325  -24.092 34.807  1.000 93.618  0 179 LEU HHH CD2 1 ? 
ATOM   1288 N N   . TYR A 1 180 ? -6.945  -24.367 30.850  1.000 79.332  0 180 TYR HHH N   1 ? 
ATOM   1289 C CA  . TYR A 1 180 ? -5.712  -24.262 30.035  1.000 84.688  0 180 TYR HHH CA  1 ? 
ATOM   1290 C C   . TYR A 1 180 ? -4.527  -24.782 30.853  1.000 82.230  0 180 TYR HHH C   1 ? 
ATOM   1291 O O   . TYR A 1 180 ? -4.629  -24.912 32.089  1.000 78.744  0 180 TYR HHH O   1 ? 
ATOM   1292 C CB  . TYR A 1 180 ? -5.476  -22.823 29.578  1.000 89.707  0 180 TYR HHH CB  1 ? 
ATOM   1293 C CG  . TYR A 1 180 ? -6.517  -22.293 28.628  1.000 92.862  0 180 TYR HHH CG  1 ? 
ATOM   1294 C CD1 . TYR A 1 180 ? -6.652  -22.810 27.350  1.000 89.389  0 180 TYR HHH CD1 1 ? 
ATOM   1295 C CD2 . TYR A 1 180 ? -7.356  -21.256 29.003  1.000 98.581  0 180 TYR HHH CD2 1 ? 
ATOM   1296 C CE1 . TYR A 1 180 ? -7.607  -22.322 26.472  1.000 99.091  0 180 TYR HHH CE1 1 ? 
ATOM   1297 C CE2 . TYR A 1 180 ? -8.320  -20.759 28.138  1.000 103.846 0 180 TYR HHH CE2 1 ? 
ATOM   1298 C CZ  . TYR A 1 180 ? -8.443  -21.291 26.865  1.000 102.901 0 180 TYR HHH CZ  1 ? 
ATOM   1299 O OH  . TYR A 1 180 ? -9.381  -20.799 26.006  1.000 99.924  0 180 TYR HHH OH  1 ? 
ATOM   1300 N N   . SER A 1 181 ? -3.425  -25.059 30.158  1.000 81.928  0 181 SER HHH N   1 ? 
ATOM   1301 C CA  . SER A 1 181 ? -2.148  -25.536 30.738  1.000 85.614  0 181 SER HHH CA  1 ? 
ATOM   1302 C C   . SER A 1 181 ? -1.015  -25.339 29.730  1.000 80.764  0 181 SER HHH C   1 ? 
ATOM   1303 O O   . SER A 1 181 ? -1.050  -25.978 28.675  1.000 85.799  0 181 SER HHH O   1 ? 
ATOM   1304 C CB  . SER A 1 181 ? -2.265  -26.975 31.156  1.000 87.669  0 181 SER HHH CB  1 ? 
ATOM   1305 O OG  . SER A 1 181 ? -0.982  -27.536 31.388  1.000 90.936  0 181 SER HHH OG  1 ? 
ATOM   1306 N N   . LEU A 1 182 ? -0.033  -24.507 30.067  1.000 78.601  0 182 LEU HHH N   1 ? 
ATOM   1307 C CA  . LEU A 1 182 ? 1.221   -24.381 29.285  1.000 81.809  0 182 LEU HHH CA  1 ? 
ATOM   1308 C C   . LEU A 1 182 ? 2.403   -24.821 30.144  1.000 79.501  0 182 LEU HHH C   1 ? 
ATOM   1309 O O   . LEU A 1 182 ? 2.245   -25.010 31.360  1.000 93.701  0 182 LEU HHH O   1 ? 
ATOM   1310 C CB  . LEU A 1 182 ? 1.401   -22.940 28.803  1.000 85.921  0 182 LEU HHH CB  1 ? 
ATOM   1311 C CG  . LEU A 1 182 ? 1.519   -21.876 29.890  1.000 91.460  0 182 LEU HHH CG  1 ? 
ATOM   1312 C CD1 . LEU A 1 182 ? 2.912   -21.850 30.489  1.000 91.886  0 182 LEU HHH CD1 1 ? 
ATOM   1313 C CD2 . LEU A 1 182 ? 1.156   -20.502 29.339  1.000 89.167  0 182 LEU HHH CD2 1 ? 
ATOM   1314 N N   . SER A 1 183 ? 3.558   -24.954 29.512  1.000 72.110  0 183 SER HHH N   1 ? 
ATOM   1315 C CA  . SER A 1 183 ? 4.847   -25.218 30.185  1.000 68.795  0 183 SER HHH CA  1 ? 
ATOM   1316 C C   . SER A 1 183 ? 5.849   -24.170 29.701  1.000 60.619  0 183 SER HHH C   1 ? 
ATOM   1317 O O   . SER A 1 183 ? 5.814   -23.840 28.515  1.000 50.720  0 183 SER HHH O   1 ? 
ATOM   1318 C CB  . SER A 1 183 ? 5.295   -26.628 29.923  1.000 69.145  0 183 SER HHH CB  1 ? 
ATOM   1319 O OG  . SER A 1 183 ? 5.460   -26.856 28.531  1.000 70.116  0 183 SER HHH OG  1 ? 
ATOM   1320 N N   . SER A 1 184 ? 6.657   -23.622 30.603  1.000 60.351  0 184 SER HHH N   1 ? 
ATOM   1321 C CA  . SER A 1 184 ? 7.786   -22.739 30.236  1.000 61.592  0 184 SER HHH CA  1 ? 
ATOM   1322 C C   . SER A 1 184 ? 9.069   -23.468 30.580  1.000 58.703  0 184 SER HHH C   1 ? 
ATOM   1323 O O   . SER A 1 184 ? 9.191   -23.876 31.720  1.000 64.860  0 184 SER HHH O   1 ? 
ATOM   1324 C CB  . SER A 1 184 ? 7.728   -21.421 30.908  1.000 60.878  0 184 SER HHH CB  1 ? 
ATOM   1325 O OG  . SER A 1 184 ? 8.742   -20.595 30.364  1.000 69.277  0 184 SER HHH OG  1 ? 
ATOM   1326 N N   . VAL A 1 185 ? 9.955   -23.653 29.609  1.000 62.741  0 185 VAL HHH N   1 ? 
ATOM   1327 C CA  . VAL A 1 185 ? 11.236  -24.384 29.812  1.000 65.784  0 185 VAL HHH CA  1 ? 
ATOM   1328 C C   . VAL A 1 185 ? 12.402  -23.479 29.412  1.000 66.206  0 185 VAL HHH C   1 ? 
ATOM   1329 O O   . VAL A 1 185 ? 12.232  -22.576 28.562  1.000 62.751  0 185 VAL HHH O   1 ? 
ATOM   1330 C CB  . VAL A 1 185 ? 11.272  -25.710 29.034  1.000 69.817  0 185 VAL HHH CB  1 ? 
ATOM   1331 C CG1 . VAL A 1 185 ? 10.097  -26.608 29.389  1.000 69.773  0 185 VAL HHH CG1 1 ? 
ATOM   1332 C CG2 . VAL A 1 185 ? 11.345  -25.475 27.535  1.000 79.428  0 185 VAL HHH CG2 1 ? 
ATOM   1333 N N   . VAL A 1 186 ? 13.557  -23.747 30.007  1.000 66.795  0 186 VAL HHH N   1 ? 
ATOM   1334 C CA  . VAL A 1 186 ? 14.807  -22.992 29.740  1.000 72.493  0 186 VAL HHH CA  1 ? 
ATOM   1335 C C   . VAL A 1 186 ? 15.987  -23.964 29.829  1.000 70.397  0 186 VAL HHH C   1 ? 
ATOM   1336 O O   . VAL A 1 186 ? 16.066  -24.708 30.817  1.000 59.391  0 186 VAL HHH O   1 ? 
ATOM   1337 C CB  . VAL A 1 186 ? 14.927  -21.800 30.707  1.000 75.857  0 186 VAL HHH CB  1 ? 
ATOM   1338 C CG1 . VAL A 1 186 ? 14.595  -22.191 32.144  1.000 85.033  0 186 VAL HHH CG1 1 ? 
ATOM   1339 C CG2 . VAL A 1 186 ? 16.290  -21.133 30.621  1.000 72.112  0 186 VAL HHH CG2 1 ? 
ATOM   1340 N N   . THR A 1 187 ? 16.847  -23.953 28.809  1.000 80.688  0 187 THR HHH N   1 ? 
ATOM   1341 C CA  . THR A 1 187 ? 18.155  -24.655 28.782  1.000 92.076  0 187 THR HHH CA  1 ? 
ATOM   1342 C C   . THR A 1 187 ? 19.202  -23.750 29.443  1.000 91.883  0 187 THR HHH C   1 ? 
ATOM   1343 O O   . THR A 1 187 ? 19.191  -22.532 29.167  1.000 89.390  0 187 THR HHH O   1 ? 
ATOM   1344 C CB  . THR A 1 187 ? 18.532  -25.058 27.350  1.000 103.006 0 187 THR HHH CB  1 ? 
ATOM   1345 O OG1 . THR A 1 187 ? 17.528  -25.953 26.876  1.000 104.274 0 187 THR HHH OG1 1 ? 
ATOM   1346 C CG2 . THR A 1 187 ? 19.878  -25.742 27.244  1.000 115.772 0 187 THR HHH CG2 1 ? 
ATOM   1347 N N   . VAL A 1 188 ? 20.068  -24.331 30.278  1.000 95.236  0 188 VAL HHH N   1 ? 
ATOM   1348 C CA  . VAL A 1 188 ? 21.112  -23.600 31.057  1.000 101.276 0 188 VAL HHH CA  1 ? 
ATOM   1349 C C   . VAL A 1 188 ? 22.343  -24.497 31.217  1.000 101.226 0 188 VAL HHH C   1 ? 
ATOM   1350 O O   . VAL A 1 188 ? 22.221  -25.722 31.191  1.000 85.308  0 188 VAL HHH O   1 ? 
ATOM   1351 C CB  . VAL A 1 188 ? 20.555  -23.138 32.421  1.000 97.839  0 188 VAL HHH CB  1 ? 
ATOM   1352 C CG1 . VAL A 1 188 ? 19.679  -21.900 32.289  1.000 94.870  0 188 VAL HHH CG1 1 ? 
ATOM   1353 C CG2 . VAL A 1 188 ? 19.802  -24.254 33.130  1.000 96.949  0 188 VAL HHH CG2 1 ? 
ATOM   1354 N N   . PRO A 1 189 ? 23.564  -23.920 31.363  1.000 100.457 0 189 PRO HHH N   1 ? 
ATOM   1355 C CA  . PRO A 1 189 ? 24.760  -24.703 31.690  1.000 96.329  0 189 PRO HHH CA  1 ? 
ATOM   1356 C C   . PRO A 1 189 ? 24.560  -25.626 32.904  1.000 88.632  0 189 PRO HHH C   1 ? 
ATOM   1357 O O   . PRO A 1 189 ? 24.061  -25.179 33.901  1.000 92.814  0 189 PRO HHH O   1 ? 
ATOM   1358 C CB  . PRO A 1 189 ? 25.804  -23.619 32.001  1.000 96.772  0 189 PRO HHH CB  1 ? 
ATOM   1359 C CG  . PRO A 1 189 ? 25.370  -22.444 31.153  1.000 94.552  0 189 PRO HHH CG  1 ? 
ATOM   1360 C CD  . PRO A 1 189 ? 23.861  -22.487 31.194  1.000 92.713  0 189 PRO HHH CD  1 ? 
ATOM   1361 N N   . SER A 1 190 ? 24.949  -26.894 32.791  1.000 94.528  0 190 SER HHH N   1 ? 
ATOM   1362 C CA  . SER A 1 190 ? 24.739  -27.925 33.841  1.000 106.498 0 190 SER HHH CA  1 ? 
ATOM   1363 C C   . SER A 1 190 ? 25.632  -27.646 35.061  1.000 113.172 0 190 SER HHH C   1 ? 
ATOM   1364 O O   . SER A 1 190 ? 25.344  -28.215 36.130  1.000 117.766 0 190 SER HHH O   1 ? 
ATOM   1365 C CB  . SER A 1 190 ? 24.966  -29.309 33.293  1.000 109.546 0 190 SER HHH CB  1 ? 
ATOM   1366 O OG  . SER A 1 190 ? 26.318  -29.476 32.902  1.000 123.775 0 190 SER HHH OG  1 ? 
ATOM   1367 N N   . SER A 1 191 ? 26.671  -26.814 34.908  1.000 120.747 0 191 SER HHH N   1 ? 
ATOM   1368 C CA  . SER A 1 191 ? 27.579  -26.358 36.000  1.000 122.969 0 191 SER HHH CA  1 ? 
ATOM   1369 C C   . SER A 1 191 ? 26.836  -25.411 36.955  1.000 124.749 0 191 SER HHH C   1 ? 
ATOM   1370 O O   . SER A 1 191 ? 26.961  -25.605 38.178  1.000 123.202 0 191 SER HHH O   1 ? 
ATOM   1371 C CB  . SER A 1 191 ? 28.841  -25.714 35.452  1.000 125.096 0 191 SER HHH CB  1 ? 
ATOM   1372 O OG  . SER A 1 191 ? 28.547  -24.570 34.654  1.000 119.884 0 191 SER HHH OG  1 ? 
ATOM   1373 N N   . SER A 1 192 ? 26.081  -24.438 36.422  1.000 124.767 0 192 SER HHH N   1 ? 
ATOM   1374 C CA  . SER A 1 192 ? 25.380  -23.375 37.196  1.000 119.283 0 192 SER HHH CA  1 ? 
ATOM   1375 C C   . SER A 1 192 ? 24.235  -23.963 38.036  1.000 114.839 0 192 SER HHH C   1 ? 
ATOM   1376 O O   . SER A 1 192 ? 23.697  -23.218 38.868  1.000 112.549 0 192 SER HHH O   1 ? 
ATOM   1377 C CB  . SER A 1 192 ? 24.890  -22.258 36.298  1.000 121.233 0 192 SER HHH CB  1 ? 
ATOM   1378 O OG  . SER A 1 192 ? 24.125  -22.767 35.213  1.000 135.834 0 192 SER HHH OG  1 ? 
ATOM   1379 N N   . LEU A 1 193 ? 23.881  -25.242 37.848  1.000 115.140 0 193 LEU HHH N   1 ? 
ATOM   1380 C CA  . LEU A 1 193 ? 22.865  -25.954 38.682  1.000 126.076 0 193 LEU HHH CA  1 ? 
ATOM   1381 C C   . LEU A 1 193 ? 23.251  -25.901 40.169  1.000 134.008 0 193 LEU HHH C   1 ? 
ATOM   1382 O O   . LEU A 1 193 ? 22.335  -25.794 41.013  1.000 136.644 0 193 LEU HHH O   1 ? 
ATOM   1383 C CB  . LEU A 1 193 ? 22.728  -27.414 38.231  1.000 121.885 0 193 LEU HHH CB  1 ? 
ATOM   1384 C CG  . LEU A 1 193 ? 21.874  -27.680 36.990  1.000 117.698 0 193 LEU HHH CG  1 ? 
ATOM   1385 C CD1 . LEU A 1 193 ? 21.606  -29.173 36.848  1.000 112.628 0 193 LEU HHH CD1 1 ? 
ATOM   1386 C CD2 . LEU A 1 193 ? 20.558  -26.910 37.027  1.000 114.916 0 193 LEU HHH CD2 1 ? 
ATOM   1387 N N   . GLY A 1 194 ? 24.550  -25.995 40.476  1.000 136.505 0 194 GLY HHH N   1 ? 
ATOM   1388 C CA  . GLY A 1 194 ? 25.081  -26.058 41.850  1.000 131.712 0 194 GLY HHH CA  1 ? 
ATOM   1389 C C   . GLY A 1 194 ? 25.110  -24.700 42.531  1.000 123.070 0 194 GLY HHH C   1 ? 
ATOM   1390 O O   . GLY A 1 194 ? 25.267  -24.676 43.764  1.000 125.028 0 194 GLY HHH O   1 ? 
ATOM   1391 N N   . THR A 1 195 ? 24.969  -23.608 41.774  1.000 121.148 0 195 THR HHH N   1 ? 
ATOM   1392 C CA  . THR A 1 195 ? 25.046  -22.217 42.297  1.000 118.373 0 195 THR HHH CA  1 ? 
ATOM   1393 C C   . THR A 1 195 ? 23.740  -21.476 41.995  1.000 118.977 0 195 THR HHH C   1 ? 
ATOM   1394 O O   . THR A 1 195 ? 22.920  -21.342 42.926  1.000 119.484 0 195 THR HHH O   1 ? 
ATOM   1395 C CB  . THR A 1 195 ? 26.272  -21.490 41.732  1.000 110.827 0 195 THR HHH CB  1 ? 
ATOM   1396 O OG1 . THR A 1 195 ? 26.164  -21.474 40.308  1.000 110.611 0 195 THR HHH OG1 1 ? 
ATOM   1397 C CG2 . THR A 1 195 ? 27.572  -22.147 42.136  1.000 111.785 0 195 THR HHH CG2 1 ? 
ATOM   1398 N N   . GLN A 1 196 ? 23.568  -21.033 40.743  1.000 119.880 0 196 GLN HHH N   1 ? 
ATOM   1399 C CA  . GLN A 1 196 ? 22.467  -20.141 40.283  1.000 112.098 0 196 GLN HHH CA  1 ? 
ATOM   1400 C C   . GLN A 1 196 ? 21.117  -20.750 40.694  1.000 108.209 0 196 GLN HHH C   1 ? 
ATOM   1401 O O   . GLN A 1 196 ? 20.910  -21.966 40.474  1.000 96.445  0 196 GLN HHH O   1 ? 
ATOM   1402 C CB  . GLN A 1 196 ? 22.571  -19.919 38.768  1.000 105.584 0 196 GLN HHH CB  1 ? 
ATOM   1403 C CG  . GLN A 1 196 ? 21.614  -18.863 38.238  1.000 110.229 0 196 GLN HHH CG  1 ? 
ATOM   1404 C CD  . GLN A 1 196 ? 21.879  -17.492 38.812  1.000 110.363 0 196 GLN HHH CD  1 ? 
ATOM   1405 O OE1 . GLN A 1 196 ? 22.991  -16.971 38.744  1.000 112.585 0 196 GLN HHH OE1 1 ? 
ATOM   1406 N NE2 . GLN A 1 196 ? 20.848  -16.890 39.378  1.000 112.148 0 196 GLN HHH NE2 1 ? 
ATOM   1407 N N   . THR A 1 197 ? 20.243  -19.944 41.304  1.000 108.208 0 197 THR HHH N   1 ? 
ATOM   1408 C CA  . THR A 1 197 ? 18.863  -20.352 41.683  1.000 102.034 0 197 THR HHH CA  1 ? 
ATOM   1409 C C   . THR A 1 197 ? 17.944  -20.002 40.509  1.000 101.780 0 197 THR HHH C   1 ? 
ATOM   1410 O O   . THR A 1 197 ? 18.157  -18.947 39.873  1.000 91.120  0 197 THR HHH O   1 ? 
ATOM   1411 C CB  . THR A 1 197 ? 18.400  -19.730 43.009  1.000 101.027 0 197 THR HHH CB  1 ? 
ATOM   1412 O OG1 . THR A 1 197 ? 17.979  -18.384 42.786  1.000 101.091 0 197 THR HHH OG1 1 ? 
ATOM   1413 C CG2 . THR A 1 197 ? 19.464  -19.762 44.087  1.000 103.898 0 197 THR HHH CG2 1 ? 
ATOM   1414 N N   . TYR A 1 198 ? 16.981  -20.876 40.224  1.000 101.748 0 198 TYR HHH N   1 ? 
ATOM   1415 C CA  . TYR A 1 198 ? 16.065  -20.776 39.064  1.000 87.902  0 198 TYR HHH CA  1 ? 
ATOM   1416 C C   . TYR A 1 198 ? 14.632  -20.687 39.588  1.000 84.197  0 198 TYR HHH C   1 ? 
ATOM   1417 O O   . TYR A 1 198 ? 14.060  -21.709 40.030  1.000 80.496  0 198 TYR HHH O   1 ? 
ATOM   1418 C CB  . TYR A 1 198 ? 16.319  -21.954 38.125  1.000 93.542  0 198 TYR HHH CB  1 ? 
ATOM   1419 C CG  . TYR A 1 198 ? 17.682  -21.946 37.477  1.000 96.853  0 198 TYR HHH CG  1 ? 
ATOM   1420 C CD1 . TYR A 1 198 ? 18.064  -20.930 36.611  1.000 94.378  0 198 TYR HHH CD1 1 ? 
ATOM   1421 C CD2 . TYR A 1 198 ? 18.597  -22.956 37.723  1.000 101.973 0 198 TYR HHH CD2 1 ? 
ATOM   1422 C CE1 . TYR A 1 198 ? 19.309  -20.925 35.996  1.000 100.088 0 198 TYR HHH CE1 1 ? 
ATOM   1423 C CE2 . TYR A 1 198 ? 19.846  -22.966 37.119  1.000 111.316 0 198 TYR HHH CE2 1 ? 
ATOM   1424 C CZ  . TYR A 1 198 ? 20.210  -21.945 36.253  1.000 107.904 0 198 TYR HHH CZ  1 ? 
ATOM   1425 O OH  . TYR A 1 198 ? 21.447  -21.954 35.665  1.000 103.595 0 198 TYR HHH OH  1 ? 
ATOM   1426 N N   . ILE A 1 199 ? 14.080  -19.475 39.575  1.000 82.883  0 199 ILE HHH N   1 ? 
ATOM   1427 C CA  . ILE A 1 199 ? 12.691  -19.198 40.037  1.000 85.914  0 199 ILE HHH CA  1 ? 
ATOM   1428 C C   . ILE A 1 199 ? 11.897  -18.684 38.840  1.000 86.613  0 199 ILE HHH C   1 ? 
ATOM   1429 O O   . ILE A 1 199 ? 12.227  -17.591 38.344  1.000 105.247 0 199 ILE HHH O   1 ? 
ATOM   1430 C CB  . ILE A 1 199 ? 12.689  -18.198 41.208  1.000 87.483  0 199 ILE HHH CB  1 ? 
ATOM   1431 C CG1 . ILE A 1 199 ? 13.423  -18.761 42.432  1.000 82.142  0 199 ILE HHH CG1 1 ? 
ATOM   1432 C CG2 . ILE A 1 199 ? 11.263  -17.790 41.544  1.000 90.837  0 199 ILE HHH CG2 1 ? 
ATOM   1433 C CD1 . ILE A 1 199 ? 14.108  -17.724 43.291  1.000 78.644  0 199 ILE HHH CD1 1 ? 
ATOM   1434 N N   . CYS A 1 200 ? 10.903  -19.441 38.381  1.000 83.274  0 200 CYS HHH N   1 ? 
ATOM   1435 C CA  . CYS A 1 200 ? 9.999   -18.981 37.299  1.000 87.294  0 200 CYS HHH CA  1 ? 
ATOM   1436 C C   . CYS A 1 200 ? 8.828   -18.237 37.927  1.000 84.112  0 200 CYS HHH C   1 ? 
ATOM   1437 O O   . CYS A 1 200 ? 8.320   -18.681 38.976  1.000 84.691  0 200 CYS HHH O   1 ? 
ATOM   1438 C CB  . CYS A 1 200 ? 9.501   -20.106 36.410  1.000 86.989  0 200 CYS HHH CB  1 ? 
ATOM   1439 S SG  . CYS A 1 200 ? 8.431   -21.294 37.250  1.000 94.653  0 200 CYS HHH SG  1 ? 
ATOM   1440 N N   . ASN A 1 201 ? 8.468   -17.117 37.315  1.000 78.731  0 201 ASN HHH N   1 ? 
ATOM   1441 C CA  . ASN A 1 201 ? 7.433   -16.198 37.831  1.000 80.764  0 201 ASN HHH CA  1 ? 
ATOM   1442 C C   . ASN A 1 201 ? 6.240   -16.269 36.883  1.000 75.526  0 201 ASN HHH C   1 ? 
ATOM   1443 O O   . ASN A 1 201 ? 6.458   -16.197 35.672  1.000 77.379  0 201 ASN HHH O   1 ? 
ATOM   1444 C CB  . ASN A 1 201 ? 8.029   -14.808 38.003  1.000 87.436  0 201 ASN HHH CB  1 ? 
ATOM   1445 C CG  . ASN A 1 201 ? 9.086   -14.792 39.077  1.000 92.843  0 201 ASN HHH CG  1 ? 
ATOM   1446 O OD1 . ASN A 1 201 ? 9.064   -15.606 39.994  1.000 120.277 0 201 ASN HHH OD1 1 ? 
ATOM   1447 N ND2 . ASN A 1 201 ? 9.978   -13.832 39.011  1.000 97.734  0 201 ASN HHH ND2 1 ? 
ATOM   1448 N N   . VAL A 1 202 ? 5.037   -16.434 37.428  1.000 72.550  0 202 VAL HHH N   1 ? 
ATOM   1449 C CA  . VAL A 1 202 ? 3.818   -16.775 36.645  1.000 72.705  0 202 VAL HHH CA  1 ? 
ATOM   1450 C C   . VAL A 1 202 ? 2.758   -15.710 36.918  1.000 79.393  0 202 VAL HHH C   1 ? 
ATOM   1451 O O   . VAL A 1 202 ? 2.083   -15.774 37.971  1.000 84.790  0 202 VAL HHH O   1 ? 
ATOM   1452 C CB  . VAL A 1 202 ? 3.312   -18.189 36.975  1.000 64.017  0 202 VAL HHH CB  1 ? 
ATOM   1453 C CG1 . VAL A 1 202 ? 2.062   -18.510 36.180  1.000 60.044  0 202 VAL HHH CG1 1 ? 
ATOM   1454 C CG2 . VAL A 1 202 ? 4.393   -19.241 36.756  1.000 62.559  0 202 VAL HHH CG2 1 ? 
ATOM   1455 N N   . ASN A 1 203 ? 2.616   -14.777 35.982  1.000 81.489  0 203 ASN HHH N   1 ? 
ATOM   1456 C CA  . ASN A 1 203 ? 1.581   -13.721 36.040  1.000 87.715  0 203 ASN HHH CA  1 ? 
ATOM   1457 C C   . ASN A 1 203 ? 0.295   -14.250 35.387  1.000 87.831  0 203 ASN HHH C   1 ? 
ATOM   1458 O O   . ASN A 1 203 ? 0.393   -15.009 34.416  1.000 92.690  0 203 ASN HHH O   1 ? 
ATOM   1459 C CB  . ASN A 1 203 ? 2.110   -12.436 35.410  1.000 95.997  0 203 ASN HHH CB  1 ? 
ATOM   1460 C CG  . ASN A 1 203 ? 1.394   -11.215 35.939  1.000 104.352 0 203 ASN HHH CG  1 ? 
ATOM   1461 O OD1 . ASN A 1 203 ? 1.839   -10.615 36.915  1.000 108.155 0 203 ASN HHH OD1 1 ? 
ATOM   1462 N ND2 . ASN A 1 203 ? 0.271   -10.869 35.325  1.000 110.209 0 203 ASN HHH ND2 1 ? 
ATOM   1463 N N   . HIS A 1 204 ? -0.864  -13.848 35.917  1.000 87.229  0 204 HIS HHH N   1 ? 
ATOM   1464 C CA  . HIS A 1 204 ? -2.220  -14.212 35.424  1.000 85.581  0 204 HIS HHH CA  1 ? 
ATOM   1465 C C   . HIS A 1 204 ? -3.182  -13.067 35.749  1.000 86.198  0 204 HIS HHH C   1 ? 
ATOM   1466 O O   . HIS A 1 204 ? -3.988  -13.247 36.677  1.000 88.051  0 204 HIS HHH O   1 ? 
ATOM   1467 C CB  . HIS A 1 204 ? -2.666  -15.545 36.046  1.000 81.902  0 204 HIS HHH CB  1 ? 
ATOM   1468 C CG  . HIS A 1 204 ? -3.958  -16.073 35.510  1.000 84.062  0 204 HIS HHH CG  1 ? 
ATOM   1469 N ND1 . HIS A 1 204 ? -4.295  -15.987 34.174  1.000 85.305  0 204 HIS HHH ND1 1 ? 
ATOM   1470 C CD2 . HIS A 1 204 ? -4.976  -16.739 36.100  1.000 79.231  0 204 HIS HHH CD2 1 ? 
ATOM   1471 C CE1 . HIS A 1 204 ? -5.459  -16.562 33.978  1.000 75.031  0 204 HIS HHH CE1 1 ? 
ATOM   1472 N NE2 . HIS A 1 204 ? -5.915  -17.002 35.144  1.000 72.086  0 204 HIS HHH NE2 1 ? 
ATOM   1473 N N   . LYS A 1 205 ? -3.091  -11.945 35.014  1.000 88.275  0 205 LYS HHH N   1 ? 
ATOM   1474 C CA  . LYS A 1 205 ? -3.823  -10.677 35.304  1.000 83.074  0 205 LYS HHH CA  1 ? 
ATOM   1475 C C   . LYS A 1 205 ? -5.295  -10.998 35.594  1.000 87.411  0 205 LYS HHH C   1 ? 
ATOM   1476 O O   . LYS A 1 205 ? -5.901  -10.377 36.470  1.000 81.351  0 205 LYS HHH O   1 ? 
ATOM   1477 C CB  . LYS A 1 205 ? -3.629  -9.662  34.171  1.000 69.361  0 205 LYS HHH CB  1 ? 
ATOM   1478 N N   . PRO A 1 206 ? -5.914  -11.999 34.920  1.000 84.884  0 206 PRO HHH N   1 ? 
ATOM   1479 C CA  . PRO A 1 206 ? -7.300  -12.380 35.212  1.000 90.977  0 206 PRO HHH CA  1 ? 
ATOM   1480 C C   . PRO A 1 206 ? -7.656  -12.659 36.681  1.000 88.399  0 206 PRO HHH C   1 ? 
ATOM   1481 O O   . PRO A 1 206 ? -8.755  -12.320 37.053  1.000 88.278  0 206 PRO HHH O   1 ? 
ATOM   1482 C CB  . PRO A 1 206 ? -7.482  -13.682 34.426  1.000 89.832  0 206 PRO HHH CB  1 ? 
ATOM   1483 C CG  . PRO A 1 206 ? -6.558  -13.512 33.249  1.000 87.150  0 206 PRO HHH CG  1 ? 
ATOM   1484 C CD  . PRO A 1 206 ? -5.354  -12.779 33.805  1.000 81.820  0 206 PRO HHH CD  1 ? 
ATOM   1485 N N   . SER A 1 207 ? -6.754  -13.273 37.455  1.000 90.391  0 207 SER HHH N   1 ? 
ATOM   1486 C CA  . SER A 1 207 ? -6.948  -13.598 38.897  1.000 93.506  0 207 SER HHH CA  1 ? 
ATOM   1487 C C   . SER A 1 207 ? -6.000  -12.771 39.784  1.000 90.619  0 207 SER HHH C   1 ? 
ATOM   1488 O O   . SER A 1 207 ? -5.845  -13.090 40.976  1.000 83.809  0 207 SER HHH O   1 ? 
ATOM   1489 C CB  . SER A 1 207 ? -6.792  -15.076 39.127  1.000 92.614  0 207 SER HHH CB  1 ? 
ATOM   1490 O OG  . SER A 1 207 ? -5.520  -15.517 38.682  1.000 94.917  0 207 SER HHH OG  1 ? 
ATOM   1491 N N   . ASN A 1 208 ? -5.404  -11.714 39.238  1.000 93.986  0 208 ASN HHH N   1 ? 
ATOM   1492 C CA  . ASN A 1 208 ? -4.446  -10.854 39.971  1.000 100.363 0 208 ASN HHH CA  1 ? 
ATOM   1493 C C   . ASN A 1 208 ? -3.406  -11.750 40.649  1.000 94.028  0 208 ASN HHH C   1 ? 
ATOM   1494 O O   . ASN A 1 208 ? -2.930  -11.416 41.747  1.000 100.300 0 208 ASN HHH O   1 ? 
ATOM   1495 C CB  . ASN A 1 208 ? -5.180  -9.955  40.966  1.000 110.099 0 208 ASN HHH CB  1 ? 
ATOM   1496 C CG  . ASN A 1 208 ? -4.566  -8.574  41.034  1.000 123.233 0 208 ASN HHH CG  1 ? 
ATOM   1497 O OD1 . ASN A 1 208 ? -4.424  -7.912  40.005  1.000 142.292 0 208 ASN HHH OD1 1 ? 
ATOM   1498 N ND2 . ASN A 1 208 ? -4.192  -8.134  42.226  1.000 125.308 0 208 ASN HHH ND2 1 ? 
ATOM   1499 N N   . THR A 1 209 ? -3.060  -12.859 40.006  1.000 83.973  0 209 THR HHH N   1 ? 
ATOM   1500 C CA  . THR A 1 209 ? -2.134  -13.872 40.562  1.000 75.310  0 209 THR HHH CA  1 ? 
ATOM   1501 C C   . THR A 1 209 ? -0.711  -13.556 40.084  1.000 76.717  0 209 THR HHH C   1 ? 
ATOM   1502 O O   . THR A 1 209 ? -0.569  -13.112 38.934  1.000 82.667  0 209 THR HHH O   1 ? 
ATOM   1503 C CB  . THR A 1 209 ? -2.653  -15.271 40.218  1.000 68.695  0 209 THR HHH CB  1 ? 
ATOM   1504 O OG1 . THR A 1 209 ? -3.234  -15.696 41.443  1.000 69.945  0 209 THR HHH OG1 1 ? 
ATOM   1505 C CG2 . THR A 1 209 ? -1.600  -16.254 39.753  1.000 73.162  0 209 THR HHH CG2 1 ? 
ATOM   1506 N N   . LYS A 1 210 ? 0.291   -13.763 40.945  1.000 74.105  0 210 LYS HHH N   1 ? 
ATOM   1507 C CA  . LYS A 1 210 ? 1.731   -13.838 40.570  1.000 70.870  0 210 LYS HHH CA  1 ? 
ATOM   1508 C C   . LYS A 1 210 ? 2.367   -14.946 41.421  1.000 68.436  0 210 LYS HHH C   1 ? 
ATOM   1509 O O   . LYS A 1 210 ? 2.464   -14.780 42.651  1.000 69.270  0 210 LYS HHH O   1 ? 
ATOM   1510 C CB  . LYS A 1 210 ? 2.409   -12.468 40.722  1.000 63.906  0 210 LYS HHH CB  1 ? 
ATOM   1511 N N   . VAL A 1 211 ? 2.758   -16.053 40.792  1.000 73.371  0 211 VAL HHH N   1 ? 
ATOM   1512 C CA  . VAL A 1 211 ? 3.289   -17.258 41.499  1.000 78.245  0 211 VAL HHH CA  1 ? 
ATOM   1513 C C   . VAL A 1 211 ? 4.757   -17.462 41.117  1.000 83.069  0 211 VAL HHH C   1 ? 
ATOM   1514 O O   . VAL A 1 211 ? 5.073   -17.623 39.931  1.000 84.659  0 211 VAL HHH O   1 ? 
ATOM   1515 C CB  . VAL A 1 211 ? 2.443   -18.515 41.218  1.000 72.606  0 211 VAL HHH CB  1 ? 
ATOM   1516 C CG1 . VAL A 1 211 ? 3.046   -19.760 41.844  1.000 72.089  0 211 VAL HHH CG1 1 ? 
ATOM   1517 C CG2 . VAL A 1 211 ? 1.010   -18.324 41.690  1.000 73.909  0 211 VAL HHH CG2 1 ? 
ATOM   1518 N N   . ASP A 1 212 ? 5.629   -17.474 42.121  1.000 96.918  0 212 ASP HHH N   1 ? 
ATOM   1519 C CA  . ASP A 1 212 ? 7.082   -17.750 41.973  1.000 92.299  0 212 ASP HHH CA  1 ? 
ATOM   1520 C C   . ASP A 1 212 ? 7.301   -19.227 42.357  1.000 82.948  0 212 ASP HHH C   1 ? 
ATOM   1521 O O   . ASP A 1 212 ? 6.584   -19.713 43.250  1.000 76.247  0 212 ASP HHH O   1 ? 
ATOM   1522 C CB  . ASP A 1 212 ? 7.852   -16.676 42.750  1.000 91.859  0 212 ASP HHH CB  1 ? 
ATOM   1523 C CG  . ASP A 1 212 ? 7.276   -15.274 42.546  1.000 101.783 0 212 ASP HHH CG  1 ? 
ATOM   1524 O OD1 . ASP A 1 212 ? 7.443   -14.706 41.451  1.000 101.409 0 212 ASP HHH OD1 1 ? 
ATOM   1525 O OD2 . ASP A 1 212 ? 6.622   -14.765 43.478  1.000 124.492 0 212 ASP HHH OD2 1 ? 
ATOM   1526 N N   . LYS A 1 213 ? 8.177   -19.953 41.652  1.000 78.595  0 213 LYS HHH N   1 ? 
ATOM   1527 C CA  . LYS A 1 213 ? 8.539   -21.359 41.999  1.000 74.005  0 213 LYS HHH CA  1 ? 
ATOM   1528 C C   . LYS A 1 213 ? 10.014  -21.618 41.660  1.000 74.014  0 213 LYS HHH C   1 ? 
ATOM   1529 O O   . LYS A 1 213 ? 10.346  -21.652 40.468  1.000 72.856  0 213 LYS HHH O   1 ? 
ATOM   1530 C CB  . LYS A 1 213 ? 7.638   -22.386 41.304  1.000 68.475  0 213 LYS HHH CB  1 ? 
ATOM   1531 N N   . ARG A 1 214 ? 10.851  -21.780 42.694  1.000 72.878  0 214 ARG HHH N   1 ? 
ATOM   1532 C CA  . ARG A 1 214 ? 12.241  -22.297 42.616  1.000 70.238  0 214 ARG HHH CA  1 ? 
ATOM   1533 C C   . ARG A 1 214 ? 12.200  -23.697 41.994  1.000 73.278  0 214 ARG HHH C   1 ? 
ATOM   1534 O O   . ARG A 1 214 ? 11.310  -24.484 42.357  1.000 74.698  0 214 ARG HHH O   1 ? 
ATOM   1535 C CB  . ARG A 1 214 ? 12.886  -22.346 44.006  1.000 65.466  0 214 ARG HHH CB  1 ? 
ATOM   1536 N N   . VAL A 1 215 ? 13.120  -23.980 41.076  1.000 71.730  0 215 VAL HHH N   1 ? 
ATOM   1537 C CA  . VAL A 1 215 ? 13.310  -25.322 40.463  1.000 78.776  0 215 VAL HHH CA  1 ? 
ATOM   1538 C C   . VAL A 1 215 ? 14.693  -25.814 40.888  1.000 88.487  0 215 VAL HHH C   1 ? 
ATOM   1539 O O   . VAL A 1 215 ? 15.674  -25.080 40.625  1.000 91.023  0 215 VAL HHH O   1 ? 
ATOM   1540 C CB  . VAL A 1 215 ? 13.150  -25.250 38.935  1.000 83.474  0 215 VAL HHH CB  1 ? 
ATOM   1541 C CG1 . VAL A 1 215 ? 13.279  -26.618 38.268  1.000 81.760  0 215 VAL HHH CG1 1 ? 
ATOM   1542 C CG2 . VAL A 1 215 ? 11.837  -24.576 38.562  1.000 82.054  0 215 VAL HHH CG2 1 ? 
ATOM   1543 N N   . GLU A 1 216 ? 14.747  -26.976 41.552  1.000 96.761  0 216 GLU HHH N   1 ? 
ATOM   1544 C CA  . GLU A 1 216 ? 15.953  -27.484 42.260  1.000 99.171  0 216 GLU HHH CA  1 ? 
ATOM   1545 C C   . GLU A 1 216 ? 16.049  -28.989 42.046  1.000 106.728 0 216 GLU HHH C   1 ? 
ATOM   1546 O O   . GLU A 1 216 ? 15.058  -29.689 42.240  1.000 116.964 0 216 GLU HHH O   1 ? 
ATOM   1547 C CB  . GLU A 1 216 ? 15.877  -27.120 43.744  1.000 93.182  0 216 GLU HHH CB  1 ? 
ATOM   1548 N N   . PRO A 1 217 ? 17.224  -29.514 41.622  1.000 117.265 0 217 PRO HHH N   1 ? 
ATOM   1549 C CA  . PRO A 1 217 ? 17.349  -30.922 41.225  1.000 125.074 0 217 PRO HHH CA  1 ? 
ATOM   1550 C C   . PRO A 1 217 ? 16.910  -31.920 42.313  1.000 139.003 0 217 PRO HHH C   1 ? 
ATOM   1551 O O   . PRO A 1 217 ? 17.081  -31.615 43.479  1.000 146.841 0 217 PRO HHH O   1 ? 
ATOM   1552 C CB  . PRO A 1 217 ? 18.843  -31.085 40.892  1.000 119.383 0 217 PRO HHH CB  1 ? 
ATOM   1553 C CG  . PRO A 1 217 ? 19.525  -29.878 41.511  1.000 116.998 0 217 PRO HHH CG  1 ? 
ATOM   1554 C CD  . PRO A 1 217 ? 18.491  -28.777 41.490  1.000 114.196 0 217 PRO HHH CD  1 ? 
ATOM   1555 N N   . LYS A 1 218 ? 16.346  -33.068 41.902  1.000 148.064 0 218 LYS HHH N   1 ? 
ATOM   1556 C CA  . LYS A 1 218 ? 15.711  -34.089 42.787  1.000 146.839 0 218 LYS HHH CA  1 ? 
ATOM   1557 C C   . LYS A 1 218 ? 16.790  -34.778 43.637  1.000 155.469 0 218 LYS HHH C   1 ? 
ATOM   1558 O O   . LYS A 1 218 ? 17.808  -35.208 43.057  1.000 162.164 0 218 LYS HHH O   1 ? 
ATOM   1559 C CB  . LYS A 1 218 ? 14.921  -35.105 41.953  1.000 129.388 0 218 LYS HHH CB  1 ? 
ATOM   1560 N N   . SER A 1 219 ? 16.575  -34.866 44.957  1.000 154.106 0 219 SER HHH N   1 ? 
ATOM   1561 C CA  . SER A 1 219 ? 17.520  -35.442 45.956  1.000 145.575 0 219 SER HHH CA  1 ? 
ATOM   1562 C C   . SER A 1 219 ? 17.897  -36.878 45.569  1.000 143.503 0 219 SER HHH C   1 ? 
ATOM   1563 O O   . SER A 1 219 ? 19.077  -37.230 45.542  1.000 144.392 0 219 SER HHH O   1 ? 
ATOM   1564 C CB  . SER A 1 219 ? 16.930  -35.405 47.335  1.000 132.716 0 219 SER HHH CB  1 ? 
ATOM   1565 O OG  . SER A 1 219 ? 15.792  -36.245 47.391  1.000 130.310 0 219 SER HHH OG  1 ? 
ATOM   1566 N N   . ASP B 2 1   ? -47.537 -21.864 24.219  1.000 110.354 0 1   ASP LLL N   1 ? 
ATOM   1567 C CA  . ASP B 2 1   ? -46.283 -22.474 23.688  1.000 98.477  0 1   ASP LLL CA  1 ? 
ATOM   1568 C C   . ASP B 2 1   ? -46.586 -23.171 22.357  1.000 89.382  0 1   ASP LLL C   1 ? 
ATOM   1569 O O   . ASP B 2 1   ? -46.761 -24.403 22.358  1.000 95.349  0 1   ASP LLL O   1 ? 
ATOM   1570 C CB  . ASP B 2 1   ? -45.663 -23.434 24.704  1.000 101.841 0 1   ASP LLL CB  1 ? 
ATOM   1571 C CG  . ASP B 2 1   ? -45.207 -22.770 25.994  1.000 109.727 0 1   ASP LLL CG  1 ? 
ATOM   1572 O OD1 . ASP B 2 1   ? -44.872 -21.563 25.951  1.000 92.032  0 1   ASP LLL OD1 1 ? 
ATOM   1573 O OD2 . ASP B 2 1   ? -45.193 -23.473 27.037  1.000 115.048 0 1   ASP LLL OD2 1 ? 
ATOM   1574 N N   . ILE B 2 2   ? -46.627 -22.390 21.273  1.000 84.375  0 2   ILE LLL N   1 ? 
ATOM   1575 C CA  . ILE B 2 2   ? -46.726 -22.871 19.863  1.000 78.368  0 2   ILE LLL CA  1 ? 
ATOM   1576 C C   . ILE B 2 2   ? -45.370 -23.468 19.463  1.000 77.399  0 2   ILE LLL C   1 ? 
ATOM   1577 O O   . ILE B 2 2   ? -44.339 -22.769 19.509  1.000 74.151  0 2   ILE LLL O   1 ? 
ATOM   1578 C CB  . ILE B 2 2   ? -47.164 -21.753 18.889  1.000 70.434  0 2   ILE LLL CB  1 ? 
ATOM   1579 C CG1 . ILE B 2 2   ? -48.357 -20.958 19.418  1.000 74.228  0 2   ILE LLL CG1 1 ? 
ATOM   1580 C CG2 . ILE B 2 2   ? -47.455 -22.319 17.512  1.000 67.527  0 2   ILE LLL CG2 1 ? 
ATOM   1581 C CD1 . ILE B 2 2   ? -49.091 -20.159 18.367  1.000 74.522  0 2   ILE LLL CD1 1 ? 
ATOM   1582 N N   . VAL B 2 3   ? -45.386 -24.723 19.043  1.000 77.432  0 3   VAL LLL N   1 ? 
ATOM   1583 C CA  . VAL B 2 3   ? -44.181 -25.435 18.548  1.000 79.181  0 3   VAL LLL CA  1 ? 
ATOM   1584 C C   . VAL B 2 3   ? -44.172 -25.317 17.029  1.000 75.101  0 3   VAL LLL C   1 ? 
ATOM   1585 O O   . VAL B 2 3   ? -45.086 -25.835 16.387  1.000 77.476  0 3   VAL LLL O   1 ? 
ATOM   1586 C CB  . VAL B 2 3   ? -44.175 -26.905 18.992  1.000 83.875  0 3   VAL LLL CB  1 ? 
ATOM   1587 C CG1 . VAL B 2 3   ? -42.820 -27.535 18.737  1.000 84.439  0 3   VAL LLL CG1 1 ? 
ATOM   1588 C CG2 . VAL B 2 3   ? -44.585 -27.038 20.454  1.000 93.254  0 3   VAL LLL CG2 1 ? 
ATOM   1589 N N   . LEU B 2 4   ? -43.150 -24.672 16.486  1.000 69.881  0 4   LEU LLL N   1 ? 
ATOM   1590 C CA  . LEU B 2 4   ? -42.899 -24.644 15.028  1.000 66.475  0 4   LEU LLL CA  1 ? 
ATOM   1591 C C   . LEU B 2 4   ? -41.837 -25.696 14.736  1.000 65.216  0 4   LEU LLL C   1 ? 
ATOM   1592 O O   . LEU B 2 4   ? -40.786 -25.659 15.407  1.000 68.145  0 4   LEU LLL O   1 ? 
ATOM   1593 C CB  . LEU B 2 4   ? -42.424 -23.252 14.621  1.000 63.958  0 4   LEU LLL CB  1 ? 
ATOM   1594 C CG  . LEU B 2 4   ? -43.174 -22.101 15.269  1.000 65.453  0 4   LEU LLL CG  1 ? 
ATOM   1595 C CD1 . LEU B 2 4   ? -42.375 -20.828 15.152  1.000 67.375  0 4   LEU LLL CD1 1 ? 
ATOM   1596 C CD2 . LEU B 2 4   ? -44.547 -21.937 14.653  1.000 68.095  0 4   LEU LLL CD2 1 ? 
ATOM   1597 N N   . THR B 2 5   ? -42.118 -26.609 13.808  1.000 68.359  0 5   THR LLL N   1 ? 
ATOM   1598 C CA  . THR B 2 5   ? -41.214 -27.726 13.430  1.000 72.268  0 5   THR LLL CA  1 ? 
ATOM   1599 C C   . THR B 2 5   ? -40.778 -27.525 11.980  1.000 74.669  0 5   THR LLL C   1 ? 
ATOM   1600 O O   . THR B 2 5   ? -41.581 -27.724 11.049  1.000 69.143  0 5   THR LLL O   1 ? 
ATOM   1601 C CB  . THR B 2 5   ? -41.860 -29.090 13.680  1.000 71.836  0 5   THR LLL CB  1 ? 
ATOM   1602 O OG1 . THR B 2 5   ? -43.150 -29.072 13.080  1.000 84.200  0 5   THR LLL OG1 1 ? 
ATOM   1603 C CG2 . THR B 2 5   ? -42.007 -29.411 15.151  1.000 76.128  0 5   THR LLL CG2 1 ? 
ATOM   1604 N N   . GLN B 2 6   ? -39.532 -27.113 11.813  1.000 75.785  0 6   GLN LLL N   1 ? 
ATOM   1605 C CA  . GLN B 2 6   ? -38.939 -26.887 10.484  1.000 71.929  0 6   GLN LLL CA  1 ? 
ATOM   1606 C C   . GLN B 2 6   ? -38.639 -28.235 9.836   1.000 72.447  0 6   GLN LLL C   1 ? 
ATOM   1607 O O   . GLN B 2 6   ? -38.296 -29.184 10.537  1.000 85.181  0 6   GLN LLL O   1 ? 
ATOM   1608 C CB  . GLN B 2 6   ? -37.684 -26.047 10.635  1.000 73.805  0 6   GLN LLL CB  1 ? 
ATOM   1609 C CG  . GLN B 2 6   ? -37.969 -24.610 11.026  1.000 68.468  0 6   GLN LLL CG  1 ? 
ATOM   1610 C CD  . GLN B 2 6   ? -36.669 -23.858 11.010  1.000 72.025  0 6   GLN LLL CD  1 ? 
ATOM   1611 O OE1 . GLN B 2 6   ? -35.612 -24.429 11.203  1.000 96.599  0 6   GLN LLL OE1 1 ? 
ATOM   1612 N NE2 . GLN B 2 6   ? -36.720 -22.589 10.702  1.000 74.562  0 6   GLN LLL NE2 1 ? 
ATOM   1613 N N   . SER B 2 7   ? -38.765 -28.299 8.523   1.000 76.870  0 7   SER LLL N   1 ? 
ATOM   1614 C CA  . SER B 2 7   ? -38.544 -29.522 7.723   1.000 71.095  0 7   SER LLL CA  1 ? 
ATOM   1615 C C   . SER B 2 7   ? -38.055 -29.083 6.350   1.000 72.274  0 7   SER LLL C   1 ? 
ATOM   1616 O O   . SER B 2 7   ? -38.738 -28.318 5.670   1.000 80.255  0 7   SER LLL O   1 ? 
ATOM   1617 C CB  . SER B 2 7   ? -39.797 -30.347 7.663   1.000 70.173  0 7   SER LLL CB  1 ? 
ATOM   1618 O OG  . SER B 2 7   ? -40.853 -29.639 7.038   1.000 68.550  0 7   SER LLL OG  1 ? 
ATOM   1619 N N   . PRO B 2 8   ? -36.848 -29.502 5.913   1.000 68.742  0 8   PRO LLL N   1 ? 
ATOM   1620 C CA  . PRO B 2 8   ? -36.028 -30.470 6.637   1.000 71.710  0 8   PRO LLL CA  1 ? 
ATOM   1621 C C   . PRO B 2 8   ? -35.167 -29.841 7.739   1.000 76.659  0 8   PRO LLL C   1 ? 
ATOM   1622 O O   . PRO B 2 8   ? -35.335 -28.683 8.016   1.000 87.816  0 8   PRO LLL O   1 ? 
ATOM   1623 C CB  . PRO B 2 8   ? -35.145 -30.997 5.511   1.000 70.875  0 8   PRO LLL CB  1 ? 
ATOM   1624 C CG  . PRO B 2 8   ? -34.896 -29.783 4.662   1.000 67.126  0 8   PRO LLL CG  1 ? 
ATOM   1625 C CD  . PRO B 2 8   ? -36.201 -29.025 4.688   1.000 64.491  0 8   PRO LLL CD  1 ? 
ATOM   1626 N N   . ALA B 2 9   ? -34.289 -30.625 8.359   1.000 76.999  0 9   ALA LLL N   1 ? 
ATOM   1627 C CA  . ALA B 2 9   ? -33.355 -30.153 9.406   1.000 79.124  0 9   ALA LLL CA  1 ? 
ATOM   1628 C C   . ALA B 2 9   ? -32.108 -29.592 8.722   1.000 79.183  0 9   ALA LLL C   1 ? 
ATOM   1629 O O   . ALA B 2 9   ? -31.567 -28.567 9.167   1.000 73.567  0 9   ALA LLL O   1 ? 
ATOM   1630 C CB  . ALA B 2 9   ? -33.014 -31.285 10.340  1.000 84.919  0 9   ALA LLL CB  1 ? 
ATOM   1631 N N   . SER B 2 10  ? -31.660 -30.257 7.663   1.000 79.251  0 10  SER LLL N   1 ? 
ATOM   1632 C CA  . SER B 2 10  ? -30.473 -29.834 6.884   1.000 82.509  0 10  SER LLL CA  1 ? 
ATOM   1633 C C   . SER B 2 10  ? -30.699 -30.200 5.423   1.000 76.091  0 10  SER LLL C   1 ? 
ATOM   1634 O O   . SER B 2 10  ? -31.109 -31.333 5.171   1.000 94.614  0 10  SER LLL O   1 ? 
ATOM   1635 C CB  . SER B 2 10  ? -29.214 -30.449 7.425   1.000 83.630  0 10  SER LLL CB  1 ? 
ATOM   1636 O OG  . SER B 2 10  ? -29.360 -31.848 7.564   1.000 101.440 0 10  SER LLL OG  1 ? 
ATOM   1637 N N   . LEU B 2 11  ? -30.482 -29.261 4.511   1.000 63.128  0 11  LEU LLL N   1 ? 
ATOM   1638 C CA  . LEU B 2 11  ? -30.443 -29.567 3.069   1.000 66.957  0 11  LEU LLL CA  1 ? 
ATOM   1639 C C   . LEU B 2 11  ? -29.141 -29.022 2.492   1.000 71.797  0 11  LEU LLL C   1 ? 
ATOM   1640 O O   . LEU B 2 11  ? -28.657 -27.965 2.953   1.000 78.300  0 11  LEU LLL O   1 ? 
ATOM   1641 C CB  . LEU B 2 11  ? -31.678 -29.022 2.338   1.000 71.764  0 11  LEU LLL CB  1 ? 
ATOM   1642 C CG  . LEU B 2 11  ? -31.915 -27.511 2.368   1.000 81.785  0 11  LEU LLL CG  1 ? 
ATOM   1643 C CD1 . LEU B 2 11  ? -30.949 -26.746 1.463   1.000 97.575  0 11  LEU LLL CD1 1 ? 
ATOM   1644 C CD2 . LEU B 2 11  ? -33.341 -27.207 1.951   1.000 78.997  0 11  LEU LLL CD2 1 ? 
ATOM   1645 N N   . ALA B 2 12  ? -28.593 -29.760 1.526   1.000 67.827  0 12  ALA LLL N   1 ? 
ATOM   1646 C CA  . ALA B 2 12  ? -27.444 -29.349 0.705   1.000 60.275  0 12  ALA LLL CA  1 ? 
ATOM   1647 C C   . ALA B 2 12  ? -27.965 -29.095 -0.703  1.000 58.296  0 12  ALA LLL C   1 ? 
ATOM   1648 O O   . ALA B 2 12  ? -28.681 -29.935 -1.231  1.000 66.896  0 12  ALA LLL O   1 ? 
ATOM   1649 C CB  . ALA B 2 12  ? -26.373 -30.403 0.738   1.000 64.386  0 12  ALA LLL CB  1 ? 
ATOM   1650 N N   . VAL B 2 13  ? -27.639 -27.943 -1.260  1.000 62.206  0 13  VAL LLL N   1 ? 
ATOM   1651 C CA  . VAL B 2 13  ? -28.159 -27.491 -2.574  1.000 66.531  0 13  VAL LLL CA  1 ? 
ATOM   1652 C C   . VAL B 2 13  ? -27.013 -26.866 -3.371  1.000 70.502  0 13  VAL LLL C   1 ? 
ATOM   1653 O O   . VAL B 2 13  ? -26.091 -26.313 -2.746  1.000 73.797  0 13  VAL LLL O   1 ? 
ATOM   1654 C CB  . VAL B 2 13  ? -29.328 -26.508 -2.369  1.000 67.139  0 13  VAL LLL CB  1 ? 
ATOM   1655 C CG1 . VAL B 2 13  ? -30.545 -27.232 -1.824  1.000 64.312  0 13  VAL LLL CG1 1 ? 
ATOM   1656 C CG2 . VAL B 2 13  ? -28.964 -25.327 -1.484  1.000 61.475  0 13  VAL LLL CG2 1 ? 
ATOM   1657 N N   . SER B 2 14  ? -27.084 -26.933 -4.700  1.000 67.849  0 14  SER LLL N   1 ? 
ATOM   1658 C CA  . SER B 2 14  ? -26.119 -26.262 -5.603  1.000 71.342  0 14  SER LLL CA  1 ? 
ATOM   1659 C C   . SER B 2 14  ? -26.652 -24.873 -5.931  1.000 66.824  0 14  SER LLL C   1 ? 
ATOM   1660 O O   . SER B 2 14  ? -27.855 -24.704 -6.071  1.000 67.828  0 14  SER LLL O   1 ? 
ATOM   1661 C CB  . SER B 2 14  ? -25.895 -27.079 -6.837  1.000 70.249  0 14  SER LLL CB  1 ? 
ATOM   1662 O OG  . SER B 2 14  ? -25.539 -28.405 -6.493  1.000 72.877  0 14  SER LLL OG  1 ? 
ATOM   1663 N N   . PRO B 2 15  ? -25.808 -23.827 -6.053  1.000 69.223  0 15  PRO LLL N   1 ? 
ATOM   1664 C CA  . PRO B 2 15  ? -26.276 -22.566 -6.625  1.000 73.221  0 15  PRO LLL CA  1 ? 
ATOM   1665 C C   . PRO B 2 15  ? -26.898 -22.824 -8.007  1.000 72.702  0 15  PRO LLL C   1 ? 
ATOM   1666 O O   . PRO B 2 15  ? -26.318 -23.548 -8.783  1.000 78.072  0 15  PRO LLL O   1 ? 
ATOM   1667 C CB  . PRO B 2 15  ? -25.033 -21.660 -6.691  1.000 74.604  0 15  PRO LLL CB  1 ? 
ATOM   1668 C CG  . PRO B 2 15  ? -23.851 -22.574 -6.365  1.000 75.303  0 15  PRO LLL CG  1 ? 
ATOM   1669 C CD  . PRO B 2 15  ? -24.408 -23.767 -5.613  1.000 70.533  0 15  PRO LLL CD  1 ? 
ATOM   1670 N N   . GLY B 2 16  ? -28.065 -22.236 -8.271  1.000 79.132  0 16  GLY LLL N   1 ? 
ATOM   1671 C CA  . GLY B 2 16  ? -28.826 -22.429 -9.522  1.000 75.609  0 16  GLY LLL CA  1 ? 
ATOM   1672 C C   . GLY B 2 16  ? -30.066 -23.256 -9.254  1.000 74.968  0 16  GLY LLL C   1 ? 
ATOM   1673 O O   . GLY B 2 16  ? -31.051 -23.139 -10.010 1.000 70.868  0 16  GLY LLL O   1 ? 
ATOM   1674 N N   . GLN B 2 17  ? -30.024 -24.038 -8.178  1.000 69.628  0 17  GLN LLL N   1 ? 
ATOM   1675 C CA  . GLN B 2 17  ? -31.138 -24.906 -7.737  1.000 69.300  0 17  GLN LLL CA  1 ? 
ATOM   1676 C C   . GLN B 2 17  ? -32.197 -24.070 -7.017  1.000 71.605  0 17  GLN LLL C   1 ? 
ATOM   1677 O O   . GLN B 2 17  ? -31.837 -23.074 -6.389  1.000 78.595  0 17  GLN LLL O   1 ? 
ATOM   1678 C CB  . GLN B 2 17  ? -30.615 -25.964 -6.779  1.000 65.506  0 17  GLN LLL CB  1 ? 
ATOM   1679 C CG  . GLN B 2 17  ? -31.577 -27.118 -6.642  1.000 70.358  0 17  GLN LLL CG  1 ? 
ATOM   1680 C CD  . GLN B 2 17  ? -31.339 -27.933 -5.403  1.000 67.734  0 17  GLN LLL CD  1 ? 
ATOM   1681 O OE1 . GLN B 2 17  ? -32.245 -28.114 -4.594  1.000 79.264  0 17  GLN LLL OE1 1 ? 
ATOM   1682 N NE2 . GLN B 2 17  ? -30.129 -28.450 -5.269  1.000 62.519  0 17  GLN LLL NE2 1 ? 
ATOM   1683 N N   . ARG B 2 18  ? -33.455 -24.484 -7.092  1.000 69.984  0 18  ARG LLL N   1 ? 
ATOM   1684 C CA  . ARG B 2 18  ? -34.540 -23.972 -6.215  1.000 74.541  0 18  ARG LLL CA  1 ? 
ATOM   1685 C C   . ARG B 2 18  ? -34.603 -24.857 -4.963  1.000 72.416  0 18  ARG LLL C   1 ? 
ATOM   1686 O O   . ARG B 2 18  ? -34.656 -26.098 -5.081  1.000 76.095  0 18  ARG LLL O   1 ? 
ATOM   1687 C CB  . ARG B 2 18  ? -35.888 -23.938 -6.944  1.000 79.974  0 18  ARG LLL CB  1 ? 
ATOM   1688 C CG  . ARG B 2 18  ? -37.066 -23.443 -6.116  1.000 87.795  0 18  ARG LLL CG  1 ? 
ATOM   1689 C CD  . ARG B 2 18  ? -38.346 -23.292 -6.925  1.000 93.251  0 18  ARG LLL CD  1 ? 
ATOM   1690 N NE  . ARG B 2 18  ? -39.005 -24.572 -7.214  1.000 94.229  0 18  ARG LLL NE  1 ? 
ATOM   1691 C CZ  . ARG B 2 18  ? -39.369 -25.016 -8.423  1.000 84.087  0 18  ARG LLL CZ  1 ? 
ATOM   1692 N NH1 . ARG B 2 18  ? -39.166 -24.294 -9.512  1.000 88.362  0 18  ARG LLL NH1 1 ? 
ATOM   1693 N NH2 . ARG B 2 18  ? -39.962 -26.188 -8.541  1.000 80.886  0 18  ARG LLL NH2 1 ? 
ATOM   1694 N N   . ALA B 2 19  ? -34.605 -24.223 -3.799  1.000 66.454  0 19  ALA LLL N   1 ? 
ATOM   1695 C CA  . ALA B 2 19  ? -34.722 -24.876 -2.485  1.000 61.915  0 19  ALA LLL CA  1 ? 
ATOM   1696 C C   . ALA B 2 19  ? -35.931 -24.292 -1.772  1.000 62.687  0 19  ALA LLL C   1 ? 
ATOM   1697 O O   . ALA B 2 19  ? -36.205 -23.081 -1.949  1.000 66.783  0 19  ALA LLL O   1 ? 
ATOM   1698 C CB  . ALA B 2 19  ? -33.471 -24.665 -1.680  1.000 62.054  0 19  ALA LLL CB  1 ? 
ATOM   1699 N N   . THR B 2 20  ? -36.598 -25.131 -0.987  1.000 60.794  0 20  THR LLL N   1 ? 
ATOM   1700 C CA  . THR B 2 20  ? -37.768 -24.748 -0.180  1.000 64.686  0 20  THR LLL CA  1 ? 
ATOM   1701 C C   . THR B 2 20  ? -37.633 -25.332 1.227   1.000 66.551  0 20  THR LLL C   1 ? 
ATOM   1702 O O   . THR B 2 20  ? -37.342 -26.521 1.340   1.000 65.044  0 20  THR LLL O   1 ? 
ATOM   1703 C CB  . THR B 2 20  ? -39.055 -25.180 -0.884  1.000 72.539  0 20  THR LLL CB  1 ? 
ATOM   1704 O OG1 . THR B 2 20  ? -39.005 -24.696 -2.229  1.000 73.249  0 20  THR LLL OG1 1 ? 
ATOM   1705 C CG2 . THR B 2 20  ? -40.281 -24.656 -0.171  1.000 76.978  0 20  THR LLL CG2 1 ? 
ATOM   1706 N N   . ILE B 2 21  ? -37.884 -24.501 2.244   1.000 72.362  0 21  ILE LLL N   1 ? 
ATOM   1707 C CA  . ILE B 2 21  ? -37.938 -24.879 3.688   1.000 71.136  0 21  ILE LLL CA  1 ? 
ATOM   1708 C C   . ILE B 2 21  ? -39.389 -24.808 4.158   1.000 60.151  0 21  ILE LLL C   1 ? 
ATOM   1709 O O   . ILE B 2 21  ? -40.173 -24.093 3.566   1.000 52.771  0 21  ILE LLL O   1 ? 
ATOM   1710 C CB  . ILE B 2 21  ? -37.038 -23.964 4.536   1.000 79.564  0 21  ILE LLL CB  1 ? 
ATOM   1711 C CG1 . ILE B 2 21  ? -35.558 -24.161 4.205   1.000 85.580  0 21  ILE LLL CG1 1 ? 
ATOM   1712 C CG2 . ILE B 2 21  ? -37.307 -24.160 6.016   1.000 85.911  0 21  ILE LLL CG2 1 ? 
ATOM   1713 C CD1 . ILE B 2 21  ? -34.995 -23.116 3.279   1.000 95.303  0 21  ILE LLL CD1 1 ? 
ATOM   1714 N N   . SER B 2 22  ? -39.724 -25.542 5.206   1.000 63.532  0 22  SER LLL N   1 ? 
ATOM   1715 C CA  . SER B 2 22  ? -41.116 -25.633 5.687   1.000 65.408  0 22  SER LLL CA  1 ? 
ATOM   1716 C C   . SER B 2 22  ? -41.166 -25.555 7.206   1.000 67.016  0 22  SER LLL C   1 ? 
ATOM   1717 O O   . SER B 2 22  ? -40.389 -26.253 7.870   1.000 69.211  0 22  SER LLL O   1 ? 
ATOM   1718 C CB  . SER B 2 22  ? -41.747 -26.865 5.175   1.000 60.277  0 22  SER LLL CB  1 ? 
ATOM   1719 O OG  . SER B 2 22  ? -41.691 -26.842 3.767   1.000 65.837  0 22  SER LLL OG  1 ? 
ATOM   1720 N N   . CYS B 2 23  ? -42.086 -24.730 7.696   1.000 61.333  0 23  CYS LLL N   1 ? 
ATOM   1721 C CA  . CYS B 2 23  ? -42.437 -24.573 9.118   1.000 67.473  0 23  CYS LLL CA  1 ? 
ATOM   1722 C C   . CYS B 2 23  ? -43.844 -25.150 9.306   1.000 66.107  0 23  CYS LLL C   1 ? 
ATOM   1723 O O   . CYS B 2 23  ? -44.804 -24.581 8.782   1.000 62.168  0 23  CYS LLL O   1 ? 
ATOM   1724 C CB  . CYS B 2 23  ? -42.340 -23.093 9.474   1.000 79.430  0 23  CYS LLL CB  1 ? 
ATOM   1725 S SG  . CYS B 2 23  ? -42.284 -22.762 11.250  1.000 87.827  0 23  CYS LLL SG  1 ? 
ATOM   1726 N N   . LYS B 2 24  ? -43.972 -26.284 9.984   1.000 69.983  0 24  LYS LLL N   1 ? 
ATOM   1727 C CA  . LYS B 2 24  ? -45.304 -26.762 10.440  1.000 75.553  0 24  LYS LLL CA  1 ? 
ATOM   1728 C C   . LYS B 2 24  ? -45.548 -26.130 11.819  1.000 76.443  0 24  LYS LLL C   1 ? 
ATOM   1729 O O   . LYS B 2 24  ? -44.583 -26.079 12.608  1.000 80.164  0 24  LYS LLL O   1 ? 
ATOM   1730 C CB  . LYS B 2 24  ? -45.365 -28.295 10.434  1.000 76.607  0 24  LYS LLL CB  1 ? 
ATOM   1731 C CG  . LYS B 2 24  ? -46.432 -28.912 11.328  1.000 82.501  0 24  LYS LLL CG  1 ? 
ATOM   1732 C CD  . LYS B 2 24  ? -47.831 -28.775 10.768  1.000 90.096  0 24  LYS LLL CD  1 ? 
ATOM   1733 C CE  . LYS B 2 24  ? -48.158 -29.816 9.716   1.000 92.238  0 24  LYS LLL CE  1 ? 
ATOM   1734 N NZ  . LYS B 2 24  ? -49.492 -29.582 9.118   1.000 92.813  0 24  LYS LLL NZ  1 ? 
ATOM   1735 N N   . ALA B 2 25  ? -46.767 -25.653 12.099  1.000 67.563  0 25  ALA LLL N   1 ? 
ATOM   1736 C CA  . ALA B 2 25  ? -47.161 -25.117 13.423  1.000 70.011  0 25  ALA LLL CA  1 ? 
ATOM   1737 C C   . ALA B 2 25  ? -48.248 -25.984 14.093  1.000 74.905  0 25  ALA LLL C   1 ? 
ATOM   1738 O O   . ALA B 2 25  ? -49.292 -26.285 13.460  1.000 70.057  0 25  ALA LLL O   1 ? 
ATOM   1739 C CB  . ALA B 2 25  ? -47.596 -23.688 13.288  1.000 65.705  0 25  ALA LLL CB  1 ? 
ATOM   1740 N N   . SER B 2 26  ? -48.006 -26.324 15.365  1.000 71.375  0 26  SER LLL N   1 ? 
ATOM   1741 C CA  . SER B 2 26  ? -48.897 -27.066 16.287  1.000 68.754  0 26  SER LLL CA  1 ? 
ATOM   1742 C C   . SER B 2 26  ? -50.327 -26.521 16.238  1.000 67.998  0 26  SER LLL C   1 ? 
ATOM   1743 O O   . SER B 2 26  ? -51.243 -27.307 16.473  1.000 80.961  0 26  SER LLL O   1 ? 
ATOM   1744 C CB  . SER B 2 26  ? -48.352 -26.996 17.685  1.000 70.926  0 26  SER LLL CB  1 ? 
ATOM   1745 O OG  . SER B 2 26  ? -48.252 -25.644 18.108  1.000 69.609  0 26  SER LLL OG  1 ? 
ATOM   1746 N N   . GLN B 2 27  ? -50.515 -25.223 15.997  1.000 67.603  0 27  GLN LLL N   1 ? 
ATOM   1747 C CA  . GLN B 2 27  ? -51.860 -24.597 15.861  1.000 69.285  0 27  GLN LLL CA  1 ? 
ATOM   1748 C C   . GLN B 2 27  ? -51.819 -23.502 14.793  1.000 64.824  0 27  GLN LLL C   1 ? 
ATOM   1749 O O   . GLN B 2 27  ? -50.711 -23.076 14.427  1.000 65.231  0 27  GLN LLL O   1 ? 
ATOM   1750 C CB  . GLN B 2 27  ? -52.316 -24.025 17.200  1.000 78.540  0 27  GLN LLL CB  1 ? 
ATOM   1751 C CG  . GLN B 2 27  ? -51.334 -23.020 17.780  1.000 89.232  0 27  GLN LLL CG  1 ? 
ATOM   1752 C CD  . GLN B 2 27  ? -51.418 -22.939 19.280  1.000 86.987  0 27  GLN LLL CD  1 ? 
ATOM   1753 O OE1 . GLN B 2 27  ? -50.784 -23.721 19.994  1.000 94.443  0 27  GLN LLL OE1 1 ? 
ATOM   1754 N NE2 . GLN B 2 27  ? -52.200 -21.981 19.754  1.000 78.551  0 27  GLN LLL NE2 1 ? 
ATOM   1755 N N   . SER B 2 28  ? -52.986 -23.060 14.320  1.000 64.012  0 28  SER LLL N   1 ? 
ATOM   1756 C CA  . SER B 2 28  ? -53.127 -22.014 13.270  1.000 66.910  0 28  SER LLL CA  1 ? 
ATOM   1757 C C   . SER B 2 28  ? -52.502 -20.684 13.723  1.000 64.668  0 28  SER LLL C   1 ? 
ATOM   1758 O O   . SER B 2 28  ? -52.570 -20.353 14.918  1.000 58.057  0 28  SER LLL O   1 ? 
ATOM   1759 C CB  . SER B 2 28  ? -54.561 -21.831 12.856  1.000 69.588  0 28  SER LLL CB  1 ? 
ATOM   1760 O OG  . SER B 2 28  ? -54.702 -20.670 12.049  1.000 66.060  0 28  SER LLL OG  1 ? 
ATOM   1761 N N   . LEU B 2 29  ? -51.882 -19.976 12.776  1.000 70.572  0 29  LEU LLL N   1 ? 
ATOM   1762 C CA  . LEU B 2 29  ? -51.179 -18.679 12.971  1.000 70.361  0 29  LEU LLL CA  1 ? 
ATOM   1763 C C   . LEU B 2 29  ? -52.044 -17.557 12.393  1.000 72.254  0 29  LEU LLL C   1 ? 
ATOM   1764 O O   . LEU B 2 29  ? -51.623 -16.387 12.472  1.000 72.705  0 29  LEU LLL O   1 ? 
ATOM   1765 C CB  . LEU B 2 29  ? -49.806 -18.739 12.289  1.000 65.185  0 29  LEU LLL CB  1 ? 
ATOM   1766 C CG  . LEU B 2 29  ? -48.626 -19.113 13.187  1.000 66.715  0 29  LEU LLL CG  1 ? 
ATOM   1767 C CD1 . LEU B 2 29  ? -48.984 -20.230 14.142  1.000 64.494  0 29  LEU LLL CD1 1 ? 
ATOM   1768 C CD2 . LEU B 2 29  ? -47.394 -19.497 12.377  1.000 70.780  0 29  LEU LLL CD2 1 ? 
ATOM   1769 N N   . ASP B 2 30  ? -53.213 -17.915 11.855  1.000 73.425  0 30  ASP LLL N   1 ? 
ATOM   1770 C CA  . ASP B 2 30  ? -54.131 -16.991 11.144  1.000 72.958  0 30  ASP LLL CA  1 ? 
ATOM   1771 C C   . ASP B 2 30  ? -54.883 -16.177 12.184  1.000 68.094  0 30  ASP LLL C   1 ? 
ATOM   1772 O O   . ASP B 2 30  ? -55.627 -16.771 12.962  1.000 70.726  0 30  ASP LLL O   1 ? 
ATOM   1773 C CB  . ASP B 2 30  ? -55.115 -17.736 10.241  1.000 75.374  0 30  ASP LLL CB  1 ? 
ATOM   1774 C CG  . ASP B 2 30  ? -54.450 -18.328 9.014   1.000 82.403  0 30  ASP LLL CG  1 ? 
ATOM   1775 O OD1 . ASP B 2 30  ? -53.194 -18.391 9.012   1.000 88.585  0 30  ASP LLL OD1 1 ? 
ATOM   1776 O OD2 . ASP B 2 30  ? -55.184 -18.723 8.076   1.000 84.806  0 30  ASP LLL OD2 1 ? 
ATOM   1777 N N   . TYR B 2 31  ? -54.690 -14.865 12.183  1.000 65.723  0 31  TYR LLL N   1 ? 
ATOM   1778 C CA  . TYR B 2 31  ? -55.420 -13.944 13.079  1.000 64.878  0 31  TYR LLL CA  1 ? 
ATOM   1779 C C   . TYR B 2 31  ? -55.661 -12.624 12.351  1.000 70.134  0 31  TYR LLL C   1 ? 
ATOM   1780 O O   . TYR B 2 31  ? -54.682 -11.996 11.899  1.000 87.002  0 31  TYR LLL O   1 ? 
ATOM   1781 C CB  . TYR B 2 31  ? -54.650 -13.768 14.387  1.000 63.804  0 31  TYR LLL CB  1 ? 
ATOM   1782 C CG  . TYR B 2 31  ? -55.387 -12.916 15.383  1.000 67.615  0 31  TYR LLL CG  1 ? 
ATOM   1783 C CD1 . TYR B 2 31  ? -56.645 -13.290 15.826  1.000 70.393  0 31  TYR LLL CD1 1 ? 
ATOM   1784 C CD2 . TYR B 2 31  ? -54.865 -11.724 15.852  1.000 67.543  0 31  TYR LLL CD2 1 ? 
ATOM   1785 C CE1 . TYR B 2 31  ? -57.362 -12.518 16.724  1.000 65.137  0 31  TYR LLL CE1 1 ? 
ATOM   1786 C CE2 . TYR B 2 31  ? -55.564 -10.948 16.763  1.000 73.164  0 31  TYR LLL CE2 1 ? 
ATOM   1787 C CZ  . TYR B 2 31  ? -56.822 -11.339 17.193  1.000 68.218  0 31  TYR LLL CZ  1 ? 
ATOM   1788 O OH  . TYR B 2 31  ? -57.539 -10.595 18.081  1.000 65.709  0 31  TYR LLL OH  1 ? 
ATOM   1789 N N   . GLU B 2 32  ? -56.927 -12.212 12.248  1.000 70.848  0 32  GLU LLL N   1 ? 
ATOM   1790 C CA  . GLU B 2 32  ? -57.343 -10.911 11.647  1.000 72.634  0 32  GLU LLL CA  1 ? 
ATOM   1791 C C   . GLU B 2 32  ? -56.819 -10.809 10.213  1.000 69.329  0 32  GLU LLL C   1 ? 
ATOM   1792 O O   . GLU B 2 32  ? -56.423 -9.703  9.825   1.000 84.853  0 32  GLU LLL O   1 ? 
ATOM   1793 C CB  . GLU B 2 32  ? -56.843 -9.716  12.471  1.000 76.845  0 32  GLU LLL CB  1 ? 
ATOM   1794 C CG  . GLU B 2 32  ? -57.708 -9.408  13.678  1.000 78.566  0 32  GLU LLL CG  1 ? 
ATOM   1795 C CD  . GLU B 2 32  ? -57.095 -8.512  14.741  1.000 82.291  0 32  GLU LLL CD  1 ? 
ATOM   1796 O OE1 . GLU B 2 32  ? -55.890 -8.197  14.648  1.000 88.078  0 32  GLU LLL OE1 1 ? 
ATOM   1797 O OE2 . GLU B 2 32  ? -57.827 -8.138  15.671  1.000 93.294  0 32  GLU LLL OE2 1 ? 
ATOM   1798 N N   . GLY B 2 33  ? -56.820 -11.915 9.466   1.000 70.936  0 33  GLY LLL N   1 ? 
ATOM   1799 C CA  . GLY B 2 33  ? -56.639 -11.913 8.002   1.000 76.053  0 33  GLY LLL CA  1 ? 
ATOM   1800 C C   . GLY B 2 33  ? -55.203 -12.127 7.559   1.000 78.550  0 33  GLY LLL C   1 ? 
ATOM   1801 O O   . GLY B 2 33  ? -55.003 -12.427 6.366   1.000 86.930  0 33  GLY LLL O   1 ? 
ATOM   1802 N N   . ASP B 2 34  ? -54.229 -11.954 8.454   1.000 81.129  0 34  ASP LLL N   1 ? 
ATOM   1803 C CA  . ASP B 2 34  ? -52.800 -12.262 8.172   1.000 88.212  0 34  ASP LLL CA  1 ? 
ATOM   1804 C C   . ASP B 2 34  ? -52.343 -13.399 9.108   1.000 80.869  0 34  ASP LLL C   1 ? 
ATOM   1805 O O   . ASP B 2 34  ? -53.101 -13.738 10.037  1.000 68.321  0 34  ASP LLL O   1 ? 
ATOM   1806 C CB  . ASP B 2 34  ? -51.930 -10.993 8.190   1.000 92.783  0 34  ASP LLL CB  1 ? 
ATOM   1807 C CG  . ASP B 2 34  ? -52.077 -10.097 9.410   1.000 99.118  0 34  ASP LLL CG  1 ? 
ATOM   1808 O OD1 . ASP B 2 34  ? -53.120 -9.440  9.529   1.000 109.596 0 34  ASP LLL OD1 1 ? 
ATOM   1809 O OD2 . ASP B 2 34  ? -51.137 -10.056 10.230  1.000 112.149 0 34  ASP LLL OD2 1 ? 
ATOM   1810 N N   . SER B 2 35  ? -51.181 -14.006 8.814   1.000 77.916  0 35  SER LLL N   1 ? 
ATOM   1811 C CA  . SER B 2 35  ? -50.492 -15.058 9.612   1.000 73.302  0 35  SER LLL CA  1 ? 
ATOM   1812 C C   . SER B 2 35  ? -49.149 -14.495 10.098  1.000 72.495  0 35  SER LLL C   1 ? 
ATOM   1813 O O   . SER B 2 35  ? -48.431 -13.962 9.257   1.000 81.463  0 35  SER LLL O   1 ? 
ATOM   1814 C CB  . SER B 2 35  ? -50.301 -16.300 8.789   1.000 71.662  0 35  SER LLL CB  1 ? 
ATOM   1815 O OG  . SER B 2 35  ? -51.444 -16.559 7.988   1.000 72.748  0 35  SER LLL OG  1 ? 
ATOM   1816 N N   . ASP B 2 36  ? -48.818 -14.581 11.392  1.000 69.976  0 36  ASP LLL N   1 ? 
ATOM   1817 C CA  . ASP B 2 36  ? -47.720 -13.776 11.992  1.000 68.086  0 36  ASP LLL CA  1 ? 
ATOM   1818 C C   . ASP B 2 36  ? -46.448 -14.621 11.989  1.000 65.553  0 36  ASP LLL C   1 ? 
ATOM   1819 O O   . ASP B 2 36  ? -45.807 -14.756 13.035  1.000 73.431  0 36  ASP LLL O   1 ? 
ATOM   1820 C CB  . ASP B 2 36  ? -48.118 -13.230 13.367  1.000 81.572  0 36  ASP LLL CB  1 ? 
ATOM   1821 C CG  . ASP B 2 36  ? -48.867 -11.901 13.326  1.000 90.176  0 36  ASP LLL CG  1 ? 
ATOM   1822 O OD1 . ASP B 2 36  ? -49.358 -11.519 12.237  1.000 84.758  0 36  ASP LLL OD1 1 ? 
ATOM   1823 O OD2 . ASP B 2 36  ? -48.949 -11.247 14.389  1.000 100.382 0 36  ASP LLL OD2 1 ? 
ATOM   1824 N N   . MET B 2 37  ? -46.084 -15.102 10.805  1.000 59.229  0 37  MET LLL N   1 ? 
ATOM   1825 C CA  . MET B 2 37  ? -44.975 -16.046 10.536  1.000 47.346  0 37  MET LLL CA  1 ? 
ATOM   1826 C C   . MET B 2 37  ? -43.772 -15.298 9.963   1.000 38.844  0 37  MET LLL C   1 ? 
ATOM   1827 O O   . MET B 2 37  ? -43.933 -14.699 8.905   1.000 42.012  0 37  MET LLL O   1 ? 
ATOM   1828 C CB  . MET B 2 37  ? -45.449 -17.050 9.479   1.000 54.526  0 37  MET LLL CB  1 ? 
ATOM   1829 C CG  . MET B 2 37  ? -44.389 -18.050 9.044   1.000 49.730  0 37  MET LLL CG  1 ? 
ATOM   1830 S SD  . MET B 2 37  ? -43.817 -18.937 10.515  1.000 53.589  0 37  MET LLL SD  1 ? 
ATOM   1831 C CE  . MET B 2 37  ? -42.089 -18.766 10.127  1.000 55.278  0 37  MET LLL CE  1 ? 
ATOM   1832 N N   . ASN B 2 38  ? -42.599 -15.381 10.576  1.000 33.654  0 38  ASN LLL N   1 ? 
ATOM   1833 C CA  . ASN B 2 38  ? -41.418 -14.624 10.101  1.000 40.463  0 38  ASN LLL CA  1 ? 
ATOM   1834 C C   . ASN B 2 38  ? -40.222 -15.557 9.980   1.000 45.324  0 38  ASN LLL C   1 ? 
ATOM   1835 O O   . ASN B 2 38  ? -40.047 -16.408 10.843  1.000 62.553  0 38  ASN LLL O   1 ? 
ATOM   1836 C CB  . ASN B 2 38  ? -41.045 -13.454 11.028  1.000 44.715  0 38  ASN LLL CB  1 ? 
ATOM   1837 C CG  . ASN B 2 38  ? -42.243 -12.719 11.590  1.000 41.388  0 38  ASN LLL CG  1 ? 
ATOM   1838 O OD1 . ASN B 2 38  ? -43.124 -12.296 10.850  1.000 42.887  0 38  ASN LLL OD1 1 ? 
ATOM   1839 N ND2 . ASN B 2 38  ? -42.331 -12.643 12.900  1.000 38.593  0 38  ASN LLL ND2 1 ? 
ATOM   1840 N N   . TRP B 2 39  ? -39.376 -15.316 8.997   1.000 50.418  0 39  TRP LLL N   1 ? 
ATOM   1841 C CA  . TRP B 2 39  ? -38.223 -16.172 8.658   1.000 54.840  0 39  TRP LLL CA  1 ? 
ATOM   1842 C C   . TRP B 2 39  ? -36.946 -15.348 8.766   1.000 57.079  0 39  TRP LLL C   1 ? 
ATOM   1843 O O   . TRP B 2 39  ? -36.904 -14.230 8.239   1.000 63.103  0 39  TRP LLL O   1 ? 
ATOM   1844 C CB  . TRP B 2 39  ? -38.377 -16.747 7.245   1.000 64.069  0 39  TRP LLL CB  1 ? 
ATOM   1845 C CG  . TRP B 2 39  ? -39.478 -17.749 7.064   1.000 66.573  0 39  TRP LLL CG  1 ? 
ATOM   1846 C CD1 . TRP B 2 39  ? -40.776 -17.492 6.743   1.000 65.727  0 39  TRP LLL CD1 1 ? 
ATOM   1847 C CD2 . TRP B 2 39  ? -39.365 -19.179 7.144   1.000 66.893  0 39  TRP LLL CD2 1 ? 
ATOM   1848 N NE1 . TRP B 2 39  ? -41.478 -18.658 6.633   1.000 73.457  0 39  TRP LLL NE1 1 ? 
ATOM   1849 C CE2 . TRP B 2 39  ? -40.640 -19.711 6.867   1.000 68.357  0 39  TRP LLL CE2 1 ? 
ATOM   1850 C CE3 . TRP B 2 39  ? -38.317 -20.059 7.418   1.000 72.088  0 39  TRP LLL CE3 1 ? 
ATOM   1851 C CZ2 . TRP B 2 39  ? -40.899 -21.080 6.869   1.000 72.451  0 39  TRP LLL CZ2 1 ? 
ATOM   1852 C CZ3 . TRP B 2 39  ? -38.566 -21.414 7.392   1.000 79.357  0 39  TRP LLL CZ3 1 ? 
ATOM   1853 C CH2 . TRP B 2 39  ? -39.842 -21.918 7.132   1.000 76.875  0 39  TRP LLL CH2 1 ? 
ATOM   1854 N N   . TYR B 2 40  ? -35.915 -15.948 9.343   1.000 60.896  0 40  TYR LLL N   1 ? 
ATOM   1855 C CA  . TYR B 2 40  ? -34.596 -15.329 9.564   1.000 52.892  0 40  TYR LLL CA  1 ? 
ATOM   1856 C C   . TYR B 2 40  ? -33.512 -16.197 8.950   1.000 59.813  0 40  TYR LLL C   1 ? 
ATOM   1857 O O   . TYR B 2 40  ? -33.479 -17.424 9.159   1.000 66.167  0 40  TYR LLL O   1 ? 
ATOM   1858 C CB  . TYR B 2 40  ? -34.372 -15.217 11.057  1.000 49.120  0 40  TYR LLL CB  1 ? 
ATOM   1859 C CG  . TYR B 2 40  ? -35.435 -14.408 11.743  1.000 53.494  0 40  TYR LLL CG  1 ? 
ATOM   1860 C CD1 . TYR B 2 40  ? -36.587 -14.991 12.241  1.000 51.769  0 40  TYR LLL CD1 1 ? 
ATOM   1861 C CD2 . TYR B 2 40  ? -35.277 -13.045 11.906  1.000 55.679  0 40  TYR LLL CD2 1 ? 
ATOM   1862 C CE1 . TYR B 2 40  ? -37.541 -14.234 12.897  1.000 51.710  0 40  TYR LLL CE1 1 ? 
ATOM   1863 C CE2 . TYR B 2 40  ? -36.218 -12.281 12.565  1.000 53.366  0 40  TYR LLL CE2 1 ? 
ATOM   1864 C CZ  . TYR B 2 40  ? -37.357 -12.875 13.058  1.000 53.221  0 40  TYR LLL CZ  1 ? 
ATOM   1865 O OH  . TYR B 2 40  ? -38.276 -12.105 13.701  1.000 57.681  0 40  TYR LLL OH  1 ? 
ATOM   1866 N N   . GLN B 2 41  ? -32.623 -15.544 8.225   1.000 63.891  0 41  GLN LLL N   1 ? 
ATOM   1867 C CA  . GLN B 2 41  ? -31.349 -16.137 7.763   1.000 62.544  0 41  GLN LLL CA  1 ? 
ATOM   1868 C C   . GLN B 2 41  ? -30.294 -15.781 8.802   1.000 61.194  0 41  GLN LLL C   1 ? 
ATOM   1869 O O   . GLN B 2 41  ? -30.126 -14.599 9.068   1.000 74.105  0 41  GLN LLL O   1 ? 
ATOM   1870 C CB  . GLN B 2 41  ? -31.034 -15.553 6.388   1.000 66.192  0 41  GLN LLL CB  1 ? 
ATOM   1871 C CG  . GLN B 2 41  ? -29.612 -15.767 5.909   1.000 66.662  0 41  GLN LLL CG  1 ? 
ATOM   1872 C CD  . GLN B 2 41  ? -29.384 -14.981 4.644   1.000 68.770  0 41  GLN LLL CD  1 ? 
ATOM   1873 O OE1 . GLN B 2 41  ? -29.189 -13.766 4.680   1.000 66.262  0 41  GLN LLL OE1 1 ? 
ATOM   1874 N NE2 . GLN B 2 41  ? -29.433 -15.672 3.512   1.000 66.136  0 41  GLN LLL NE2 1 ? 
ATOM   1875 N N   . GLN B 2 42  ? -29.594 -16.747 9.365   1.000 59.940  0 42  GLN LLL N   1 ? 
ATOM   1876 C CA  . GLN B 2 42  ? -28.391 -16.444 10.173  1.000 60.430  0 42  GLN LLL CA  1 ? 
ATOM   1877 C C   . GLN B 2 42  ? -27.154 -17.064 9.517   1.000 63.459  0 42  GLN LLL C   1 ? 
ATOM   1878 O O   . GLN B 2 42  ? -27.001 -18.303 9.574   1.000 58.071  0 42  GLN LLL O   1 ? 
ATOM   1879 C CB  . GLN B 2 42  ? -28.549 -16.958 11.598  1.000 62.451  0 42  GLN LLL CB  1 ? 
ATOM   1880 C CG  . GLN B 2 42  ? -27.323 -16.648 12.432  1.000 62.424  0 42  GLN LLL CG  1 ? 
ATOM   1881 C CD  . GLN B 2 42  ? -27.567 -16.895 13.890  1.000 57.838  0 42  GLN LLL CD  1 ? 
ATOM   1882 O OE1 . GLN B 2 42  ? -28.353 -17.754 14.246  1.000 57.857  0 42  GLN LLL OE1 1 ? 
ATOM   1883 N NE2 . GLN B 2 42  ? -26.874 -16.159 14.739  1.000 60.354  0 42  GLN LLL NE2 1 ? 
ATOM   1884 N N   . LYS B 2 43  ? -26.284 -16.220 8.962   1.000 70.639  0 43  LYS LLL N   1 ? 
ATOM   1885 C CA  . LYS B 2 43  ? -24.964 -16.631 8.416   1.000 74.141  0 43  LYS LLL CA  1 ? 
ATOM   1886 C C   . LYS B 2 43  ? -24.021 -16.866 9.583   1.000 75.941  0 43  LYS LLL C   1 ? 
ATOM   1887 O O   . LYS B 2 43  ? -24.134 -16.190 10.601  1.000 76.225  0 43  LYS LLL O   1 ? 
ATOM   1888 C CB  . LYS B 2 43  ? -24.408 -15.570 7.460   1.000 78.327  0 43  LYS LLL CB  1 ? 
ATOM   1889 C CG  . LYS B 2 43  ? -25.196 -15.448 6.165   1.000 79.736  0 43  LYS LLL CG  1 ? 
ATOM   1890 C CD  . LYS B 2 43  ? -24.614 -14.518 5.145   1.000 84.562  0 43  LYS LLL CD  1 ? 
ATOM   1891 C CE  . LYS B 2 43  ? -25.633 -14.167 4.082   1.000 92.147  0 43  LYS LLL CE  1 ? 
ATOM   1892 N NZ  . LYS B 2 43  ? -25.135 -13.102 3.179   1.000 95.088  0 43  LYS LLL NZ  1 ? 
ATOM   1893 N N   . PRO B 2 44  ? -23.057 -17.809 9.471   1.000 92.030  0 44  PRO LLL N   1 ? 
ATOM   1894 C CA  . PRO B 2 44  ? -22.190 -18.144 10.601  1.000 90.353  0 44  PRO LLL CA  1 ? 
ATOM   1895 C C   . PRO B 2 44  ? -21.446 -16.909 11.137  1.000 90.743  0 44  PRO LLL C   1 ? 
ATOM   1896 O O   . PRO B 2 44  ? -20.937 -16.111 10.340  1.000 82.261  0 44  PRO LLL O   1 ? 
ATOM   1897 C CB  . PRO B 2 44  ? -21.236 -19.199 10.029  1.000 87.667  0 44  PRO LLL CB  1 ? 
ATOM   1898 C CG  . PRO B 2 44  ? -22.000 -19.787 8.861   1.000 90.414  0 44  PRO LLL CG  1 ? 
ATOM   1899 C CD  . PRO B 2 44  ? -22.749 -18.611 8.273   1.000 91.676  0 44  PRO LLL CD  1 ? 
ATOM   1900 N N   . GLY B 2 45  ? -21.459 -16.766 12.468  1.000 91.862  0 45  GLY LLL N   1 ? 
ATOM   1901 C CA  . GLY B 2 45  ? -20.788 -15.689 13.219  1.000 95.688  0 45  GLY LLL CA  1 ? 
ATOM   1902 C C   . GLY B 2 45  ? -21.419 -14.324 12.991  1.000 94.865  0 45  GLY LLL C   1 ? 
ATOM   1903 O O   . GLY B 2 45  ? -20.792 -13.331 13.377  1.000 104.422 0 45  GLY LLL O   1 ? 
ATOM   1904 N N   . GLN B 2 46  ? -22.614 -14.259 12.401  1.000 91.303  0 46  GLN LLL N   1 ? 
ATOM   1905 C CA  . GLN B 2 46  ? -23.356 -12.991 12.176  1.000 86.327  0 46  GLN LLL CA  1 ? 
ATOM   1906 C C   . GLN B 2 46  ? -24.684 -13.082 12.922  1.000 75.898  0 46  GLN LLL C   1 ? 
ATOM   1907 O O   . GLN B 2 46  ? -25.150 -14.183 13.203  1.000 73.406  0 46  GLN LLL O   1 ? 
ATOM   1908 C CB  . GLN B 2 46  ? -23.533 -12.751 10.677  1.000 94.388  0 46  GLN LLL CB  1 ? 
ATOM   1909 C CG  . GLN B 2 46  ? -22.291 -12.186 10.001  1.000 100.366 0 46  GLN LLL CG  1 ? 
ATOM   1910 C CD  . GLN B 2 46  ? -22.265 -12.525 8.530   1.000 109.744 0 46  GLN LLL CD  1 ? 
ATOM   1911 O OE1 . GLN B 2 46  ? -23.067 -12.029 7.741   1.000 107.183 0 46  GLN LLL OE1 1 ? 
ATOM   1912 N NE2 . GLN B 2 46  ? -21.349 -13.403 8.154   1.000 117.508 0 46  GLN LLL NE2 1 ? 
ATOM   1913 N N   . PRO B 2 47  ? -25.310 -11.947 13.310  1.000 64.961  0 47  PRO LLL N   1 ? 
ATOM   1914 C CA  . PRO B 2 47  ? -26.652 -11.979 13.885  1.000 62.783  0 47  PRO LLL CA  1 ? 
ATOM   1915 C C   . PRO B 2 47  ? -27.658 -12.408 12.822  1.000 59.436  0 47  PRO LLL C   1 ? 
ATOM   1916 O O   . PRO B 2 47  ? -27.377 -12.315 11.634  1.000 64.380  0 47  PRO LLL O   1 ? 
ATOM   1917 C CB  . PRO B 2 47  ? -26.900 -10.531 14.327  1.000 63.958  0 47  PRO LLL CB  1 ? 
ATOM   1918 C CG  . PRO B 2 47  ? -26.013 -9.715  13.411  1.000 67.353  0 47  PRO LLL CG  1 ? 
ATOM   1919 C CD  . PRO B 2 47  ? -24.782 -10.578 13.206  1.000 66.988  0 47  PRO LLL CD  1 ? 
ATOM   1920 N N   . PRO B 2 48  ? -28.851 -12.909 13.196  1.000 56.519  0 48  PRO LLL N   1 ? 
ATOM   1921 C CA  . PRO B 2 48  ? -29.900 -13.190 12.224  1.000 57.236  0 48  PRO LLL CA  1 ? 
ATOM   1922 C C   . PRO B 2 48  ? -30.328 -11.936 11.456  1.000 59.472  0 48  PRO LLL C   1 ? 
ATOM   1923 O O   . PRO B 2 48  ? -30.222 -10.837 11.983  1.000 64.216  0 48  PRO LLL O   1 ? 
ATOM   1924 C CB  . PRO B 2 48  ? -31.053 -13.719 13.080  1.000 55.002  0 48  PRO LLL CB  1 ? 
ATOM   1925 C CG  . PRO B 2 48  ? -30.353 -14.314 14.271  1.000 55.872  0 48  PRO LLL CG  1 ? 
ATOM   1926 C CD  . PRO B 2 48  ? -29.237 -13.329 14.546  1.000 58.846  0 48  PRO LLL CD  1 ? 
ATOM   1927 N N   . ARG B 2 49  ? -30.763 -12.153 10.216  1.000 66.560  0 49  ARG LLL N   1 ? 
ATOM   1928 C CA  . ARG B 2 49  ? -31.385 -11.141 9.328   1.000 68.172  0 49  ARG LLL CA  1 ? 
ATOM   1929 C C   . ARG B 2 49  ? -32.799 -11.621 9.017   1.000 65.659  0 49  ARG LLL C   1 ? 
ATOM   1930 O O   . ARG B 2 49  ? -32.962 -12.799 8.624   1.000 74.032  0 49  ARG LLL O   1 ? 
ATOM   1931 C CB  . ARG B 2 49  ? -30.569 -10.972 8.047   1.000 71.853  0 49  ARG LLL CB  1 ? 
ATOM   1932 C CG  . ARG B 2 49  ? -30.869 -9.684  7.302   1.000 82.946  0 49  ARG LLL CG  1 ? 
ATOM   1933 C CD  . ARG B 2 49  ? -30.066 -9.535  6.018   1.000 95.432  0 49  ARG LLL CD  1 ? 
ATOM   1934 N NE  . ARG B 2 49  ? -28.700 -9.059  6.232   1.000 108.472 0 49  ARG LLL NE  1 ? 
ATOM   1935 C CZ  . ARG B 2 49  ? -28.331 -7.790  6.454   1.000 117.460 0 49  ARG LLL CZ  1 ? 
ATOM   1936 N NH1 . ARG B 2 49  ? -29.222 -6.808  6.513   1.000 119.049 0 49  ARG LLL NH1 1 ? 
ATOM   1937 N NH2 . ARG B 2 49  ? -27.050 -7.511  6.631   1.000 121.311 0 49  ARG LLL NH2 1 ? 
ATOM   1938 N N   . LEU B 2 50  ? -33.781 -10.749 9.193   1.000 61.599  0 50  LEU LLL N   1 ? 
ATOM   1939 C CA  . LEU B 2 50  ? -35.179 -11.037 8.796   1.000 62.443  0 50  LEU LLL CA  1 ? 
ATOM   1940 C C   . LEU B 2 50  ? -35.298 -11.002 7.266   1.000 59.228  0 50  LEU LLL C   1 ? 
ATOM   1941 O O   . LEU B 2 50  ? -34.794 -10.041 6.672   1.000 65.420  0 50  LEU LLL O   1 ? 
ATOM   1942 C CB  . LEU B 2 50  ? -36.068 -9.983  9.447   1.000 62.442  0 50  LEU LLL CB  1 ? 
ATOM   1943 C CG  . LEU B 2 50  ? -37.546 -10.077 9.098   1.000 64.676  0 50  LEU LLL CG  1 ? 
ATOM   1944 C CD1 . LEU B 2 50  ? -38.143 -11.381 9.617   1.000 71.395  0 50  LEU LLL CD1 1 ? 
ATOM   1945 C CD2 . LEU B 2 50  ? -38.282 -8.875  9.665   1.000 65.432  0 50  LEU LLL CD2 1 ? 
ATOM   1946 N N   . LEU B 2 51  ? -35.936 -12.003 6.650   1.000 59.283  0 51  LEU LLL N   1 ? 
ATOM   1947 C CA  . LEU B 2 51  ? -36.169 -12.045 5.178   1.000 62.069  0 51  LEU LLL CA  1 ? 
ATOM   1948 C C   . LEU B 2 51  ? -37.644 -11.802 4.870   1.000 63.426  0 51  LEU LLL C   1 ? 
ATOM   1949 O O   . LEU B 2 51  ? -37.959 -11.116 3.880   1.000 53.035  0 51  LEU LLL O   1 ? 
ATOM   1950 C CB  . LEU B 2 51  ? -35.813 -13.421 4.623   1.000 61.240  0 51  LEU LLL CB  1 ? 
ATOM   1951 C CG  . LEU B 2 51  ? -34.510 -14.029 5.096   1.000 62.084  0 51  LEU LLL CG  1 ? 
ATOM   1952 C CD1 . LEU B 2 51  ? -34.613 -15.540 5.006   1.000 62.768  0 51  LEU LLL CD1 1 ? 
ATOM   1953 C CD2 . LEU B 2 51  ? -33.354 -13.494 4.270   1.000 64.001  0 51  LEU LLL CD2 1 ? 
ATOM   1954 N N   . ILE B 2 52  ? -38.509 -12.456 5.638   1.000 67.818  0 52  ILE LLL N   1 ? 
ATOM   1955 C CA  . ILE B 2 52  ? -39.954 -12.571 5.323   1.000 62.578  0 52  ILE LLL CA  1 ? 
ATOM   1956 C C   . ILE B 2 52  ? -40.719 -12.378 6.620   1.000 60.837  0 52  ILE LLL C   1 ? 
ATOM   1957 O O   . ILE B 2 52  ? -40.509 -13.159 7.528   1.000 59.499  0 52  ILE LLL O   1 ? 
ATOM   1958 C CB  . ILE B 2 52  ? -40.233 -13.932 4.664   1.000 57.122  0 52  ILE LLL CB  1 ? 
ATOM   1959 C CG1 . ILE B 2 52  ? -39.998 -13.890 3.153   1.000 55.529  0 52  ILE LLL CG1 1 ? 
ATOM   1960 C CG2 . ILE B 2 52  ? -41.627 -14.421 4.985   1.000 62.361  0 52  ILE LLL CG2 1 ? 
ATOM   1961 C CD1 . ILE B 2 52  ? -38.784 -14.651 2.700   1.000 53.083  0 52  ILE LLL CD1 1 ? 
ATOM   1962 N N   . SER B 2 53  ? -41.562 -11.355 6.683   1.000 64.856  0 53  SER LLL N   1 ? 
ATOM   1963 C CA  . SER B 2 53  ? -42.437 -11.067 7.840   1.000 65.900  0 53  SER LLL CA  1 ? 
ATOM   1964 C C   . SER B 2 53  ? -43.889 -11.173 7.391   1.000 62.300  0 53  SER LLL C   1 ? 
ATOM   1965 O O   . SER B 2 53  ? -44.285 -10.363 6.586   1.000 74.137  0 53  SER LLL O   1 ? 
ATOM   1966 C CB  . SER B 2 53  ? -42.128 -9.708  8.421   1.000 70.321  0 53  SER LLL CB  1 ? 
ATOM   1967 O OG  . SER B 2 53  ? -42.434 -8.649  7.511   1.000 70.864  0 53  SER LLL OG  1 ? 
ATOM   1968 N N   . GLY B 2 54  ? -44.654 -12.112 7.941   1.000 66.063  0 54  GLY LLL N   1 ? 
ATOM   1969 C CA  . GLY B 2 54  ? -46.078 -12.286 7.616   1.000 61.954  0 54  GLY LLL CA  1 ? 
ATOM   1970 C C   . GLY B 2 54  ? -46.261 -13.291 6.499   1.000 64.440  0 54  GLY LLL C   1 ? 
ATOM   1971 O O   . GLY B 2 54  ? -47.234 -13.150 5.772   1.000 78.685  0 54  GLY LLL O   1 ? 
ATOM   1972 N N   . ALA B 2 55  ? -45.338 -14.248 6.356   1.000 64.494  0 55  ALA LLL N   1 ? 
ATOM   1973 C CA  . ALA B 2 55  ? -45.455 -15.428 5.472   1.000 65.308  0 55  ALA LLL CA  1 ? 
ATOM   1974 C C   . ALA B 2 55  ? -45.645 -15.009 4.021   1.000 72.779  0 55  ALA LLL C   1 ? 
ATOM   1975 O O   . ALA B 2 55  ? -46.369 -15.714 3.309   1.000 117.704 0 55  ALA LLL O   1 ? 
ATOM   1976 C CB  . ALA B 2 55  ? -46.630 -16.256 5.931   1.000 64.276  0 55  ALA LLL CB  1 ? 
ATOM   1977 N N   . SER B 2 56  ? -45.096 -13.877 3.608   1.000 73.628  0 56  SER LLL N   1 ? 
ATOM   1978 C CA  . SER B 2 56  ? -45.302 -13.348 2.237   1.000 74.998  0 56  SER LLL CA  1 ? 
ATOM   1979 C C   . SER B 2 56  ? -44.420 -12.122 2.041   1.000 67.834  0 56  SER LLL C   1 ? 
ATOM   1980 O O   . SER B 2 56  ? -43.727 -12.082 1.021   1.000 65.628  0 56  SER LLL O   1 ? 
ATOM   1981 C CB  . SER B 2 56  ? -46.761 -13.037 1.937   1.000 77.797  0 56  SER LLL CB  1 ? 
ATOM   1982 O OG  . SER B 2 56  ? -47.310 -12.160 2.911   1.000 82.107  0 56  SER LLL OG  1 ? 
ATOM   1983 N N   . ASN B 2 57  ? -44.430 -11.186 2.991   1.000 66.032  0 57  ASN LLL N   1 ? 
ATOM   1984 C CA  . ASN B 2 57  ? -43.876 -9.820  2.772   1.000 67.384  0 57  ASN LLL CA  1 ? 
ATOM   1985 C C   . ASN B 2 57  ? -42.350 -9.854  2.862   1.000 67.872  0 57  ASN LLL C   1 ? 
ATOM   1986 O O   . ASN B 2 57  ? -41.803 -10.156 3.930   1.000 72.735  0 57  ASN LLL O   1 ? 
ATOM   1987 C CB  . ASN B 2 57  ? -44.497 -8.789  3.706   1.000 63.454  0 57  ASN LLL CB  1 ? 
ATOM   1988 C CG  . ASN B 2 57  ? -46.005 -8.914  3.729   1.000 72.967  0 57  ASN LLL CG  1 ? 
ATOM   1989 O OD1 . ASN B 2 57  ? -46.691 -8.470  2.812   1.000 68.906  0 57  ASN LLL OD1 1 ? 
ATOM   1990 N ND2 . ASN B 2 57  ? -46.535 -9.552  4.760   1.000 78.910  0 57  ASN LLL ND2 1 ? 
ATOM   1991 N N   . LEU B 2 58  ? -41.691 -9.595  1.734   1.000 72.063  0 58  LEU LLL N   1 ? 
ATOM   1992 C CA  . LEU B 2 58  ? -40.219 -9.609  1.630   1.000 66.075  0 58  LEU LLL CA  1 ? 
ATOM   1993 C C   . LEU B 2 58  ? -39.719 -8.379  2.368   1.000 62.031  0 58  LEU LLL C   1 ? 
ATOM   1994 O O   . LEU B 2 58  ? -40.362 -7.316  2.259   1.000 64.472  0 58  LEU LLL O   1 ? 
ATOM   1995 C CB  . LEU B 2 58  ? -39.808 -9.577  0.160   1.000 66.917  0 58  LEU LLL CB  1 ? 
ATOM   1996 C CG  . LEU B 2 58  ? -38.448 -10.183 -0.158  1.000 72.081  0 58  LEU LLL CG  1 ? 
ATOM   1997 C CD1 . LEU B 2 58  ? -38.320 -11.587 0.429   1.000 71.422  0 58  LEU LLL CD1 1 ? 
ATOM   1998 C CD2 . LEU B 2 58  ? -38.242 -10.199 -1.661  1.000 76.395  0 58  LEU LLL CD2 1 ? 
ATOM   1999 N N   . GLU B 2 59  ? -38.617 -8.516  3.085   1.000 62.951  0 59  GLU LLL N   1 ? 
ATOM   2000 C CA  . GLU B 2 59  ? -38.031 -7.366  3.789   1.000 68.359  0 59  GLU LLL CA  1 ? 
ATOM   2001 C C   . GLU B 2 59  ? -37.197 -6.594  2.776   1.000 69.205  0 59  GLU LLL C   1 ? 
ATOM   2002 O O   . GLU B 2 59  ? -36.736 -7.231  1.789   1.000 58.313  0 59  GLU LLL O   1 ? 
ATOM   2003 C CB  . GLU B 2 59  ? -37.326 -7.840  5.047   1.000 65.850  0 59  GLU LLL CB  1 ? 
ATOM   2004 C CG  . GLU B 2 59  ? -38.333 -8.191  6.120   1.000 73.215  0 59  GLU LLL CG  1 ? 
ATOM   2005 C CD  . GLU B 2 59  ? -39.321 -7.087  6.478   1.000 76.974  0 59  GLU LLL CD  1 ? 
ATOM   2006 O OE1 . GLU B 2 59  ? -38.865 -6.024  6.968   1.000 72.042  0 59  GLU LLL OE1 1 ? 
ATOM   2007 O OE2 . GLU B 2 59  ? -40.541 -7.285  6.252   1.000 76.556  0 59  GLU LLL OE2 1 ? 
ATOM   2008 N N   . SER B 2 60  ? -37.115 -5.271  2.968   1.000 63.138  0 60  SER LLL N   1 ? 
ATOM   2009 C CA  . SER B 2 60  ? -36.349 -4.362  2.084   1.000 66.905  0 60  SER LLL CA  1 ? 
ATOM   2010 C C   . SER B 2 60  ? -34.915 -4.889  1.966   1.000 63.426  0 60  SER LLL C   1 ? 
ATOM   2011 O O   . SER B 2 60  ? -34.336 -5.265  2.993   1.000 59.696  0 60  SER LLL O   1 ? 
ATOM   2012 C CB  . SER B 2 60  ? -36.388 -2.930  2.572   1.000 66.623  0 60  SER LLL CB  1 ? 
ATOM   2013 O OG  . SER B 2 60  ? -35.580 -2.094  1.748   1.000 59.022  0 60  SER LLL OG  1 ? 
ATOM   2014 N N   . GLY B 2 61  ? -34.372 -4.918  0.750   1.000 67.708  0 61  GLY LLL N   1 ? 
ATOM   2015 C CA  . GLY B 2 61  ? -32.962 -5.264  0.505   1.000 68.465  0 61  GLY LLL CA  1 ? 
ATOM   2016 C C   . GLY B 2 61  ? -32.742 -6.760  0.537   1.000 63.032  0 61  GLY LLL C   1 ? 
ATOM   2017 O O   . GLY B 2 61  ? -31.589 -7.172  0.531   1.000 69.119  0 61  GLY LLL O   1 ? 
ATOM   2018 N N   . ILE B 2 62  ? -33.810 -7.548  0.573   1.000 60.313  0 62  ILE LLL N   1 ? 
ATOM   2019 C CA  . ILE B 2 62  ? -33.730 -9.025  0.429   1.000 63.385  0 62  ILE LLL CA  1 ? 
ATOM   2020 C C   . ILE B 2 62  ? -34.066 -9.363  -1.020  1.000 63.471  0 62  ILE LLL C   1 ? 
ATOM   2021 O O   . ILE B 2 62  ? -35.134 -9.005  -1.505  1.000 65.551  0 62  ILE LLL O   1 ? 
ATOM   2022 C CB  . ILE B 2 62  ? -34.665 -9.718  1.437   1.000 66.702  0 62  ILE LLL CB  1 ? 
ATOM   2023 C CG1 . ILE B 2 62  ? -34.390 -9.259  2.873   1.000 64.433  0 62  ILE LLL CG1 1 ? 
ATOM   2024 C CG2 . ILE B 2 62  ? -34.585 -11.232 1.301   1.000 68.850  0 62  ILE LLL CG2 1 ? 
ATOM   2025 C CD1 . ILE B 2 62  ? -33.005 -9.571  3.377   1.000 64.824  0 62  ILE LLL CD1 1 ? 
ATOM   2026 N N   . PRO B 2 63  ? -33.175 -10.057 -1.761  1.000 60.876  0 63  PRO LLL N   1 ? 
ATOM   2027 C CA  . PRO B 2 63  ? -33.474 -10.466 -3.136  1.000 64.209  0 63  PRO LLL CA  1 ? 
ATOM   2028 C C   . PRO B 2 63  ? -34.797 -11.226 -3.352  1.000 65.208  0 63  PRO LLL C   1 ? 
ATOM   2029 O O   . PRO B 2 63  ? -35.197 -12.002 -2.490  1.000 62.557  0 63  PRO LLL O   1 ? 
ATOM   2030 C CB  . PRO B 2 63  ? -32.322 -11.423 -3.495  1.000 69.940  0 63  PRO LLL CB  1 ? 
ATOM   2031 C CG  . PRO B 2 63  ? -31.183 -11.047 -2.558  1.000 66.956  0 63  PRO LLL CG  1 ? 
ATOM   2032 C CD  . PRO B 2 63  ? -31.844 -10.494 -1.312  1.000 62.498  0 63  PRO LLL CD  1 ? 
ATOM   2033 N N   . ALA B 2 64  ? -35.413 -11.020 -4.523  1.000 66.992  0 64  ALA LLL N   1 ? 
ATOM   2034 C CA  . ALA B 2 64  ? -36.675 -11.662 -4.966  1.000 67.523  0 64  ALA LLL CA  1 ? 
ATOM   2035 C C   . ALA B 2 64  ? -36.502 -13.185 -5.052  1.000 71.120  0 64  ALA LLL C   1 ? 
ATOM   2036 O O   . ALA B 2 64  ? -37.515 -13.902 -5.044  1.000 76.540  0 64  ALA LLL O   1 ? 
ATOM   2037 C CB  . ALA B 2 64  ? -37.101 -11.090 -6.296  1.000 66.643  0 64  ALA LLL CB  1 ? 
ATOM   2038 N N   . ARG B 2 65  ? -35.265 -13.671 -5.135  1.000 69.067  0 65  ARG LLL N   1 ? 
ATOM   2039 C CA  . ARG B 2 65  ? -34.957 -15.122 -5.087  1.000 69.702  0 65  ARG LLL CA  1 ? 
ATOM   2040 C C   . ARG B 2 65  ? -35.636 -15.741 -3.860  1.000 63.303  0 65  ARG LLL C   1 ? 
ATOM   2041 O O   . ARG B 2 65  ? -36.018 -16.916 -3.920  1.000 67.378  0 65  ARG LLL O   1 ? 
ATOM   2042 C CB  . ARG B 2 65  ? -33.448 -15.353 -5.035  1.000 77.115  0 65  ARG LLL CB  1 ? 
ATOM   2043 C CG  . ARG B 2 65  ? -32.641 -14.393 -5.895  1.000 84.189  0 65  ARG LLL CG  1 ? 
ATOM   2044 C CD  . ARG B 2 65  ? -31.194 -14.818 -5.999  1.000 90.332  0 65  ARG LLL CD  1 ? 
ATOM   2045 N NE  . ARG B 2 65  ? -30.375 -14.400 -4.863  1.000 92.385  0 65  ARG LLL NE  1 ? 
ATOM   2046 C CZ  . ARG B 2 65  ? -30.125 -15.124 -3.768  1.000 87.072  0 65  ARG LLL CZ  1 ? 
ATOM   2047 N NH1 . ARG B 2 65  ? -30.657 -16.327 -3.603  1.000 84.648  0 65  ARG LLL NH1 1 ? 
ATOM   2048 N NH2 . ARG B 2 65  ? -29.339 -14.622 -2.830  1.000 86.320  0 65  ARG LLL NH2 1 ? 
ATOM   2049 N N   . PHE B 2 66  ? -35.773 -14.978 -2.782  1.000 59.285  0 66  PHE LLL N   1 ? 
ATOM   2050 C CA  . PHE B 2 66  ? -36.472 -15.407 -1.550  1.000 56.994  0 66  PHE LLL CA  1 ? 
ATOM   2051 C C   . PHE B 2 66  ? -37.949 -15.069 -1.692  1.000 56.869  0 66  PHE LLL C   1 ? 
ATOM   2052 O O   . PHE B 2 66  ? -38.269 -13.965 -2.088  1.000 68.301  0 66  PHE LLL O   1 ? 
ATOM   2053 C CB  . PHE B 2 66  ? -35.875 -14.734 -0.317  1.000 59.857  0 66  PHE LLL CB  1 ? 
ATOM   2054 C CG  . PHE B 2 66  ? -34.446 -15.124 -0.044  1.000 63.547  0 66  PHE LLL CG  1 ? 
ATOM   2055 C CD1 . PHE B 2 66  ? -34.145 -16.206 0.770   1.000 65.301  0 66  PHE LLL CD1 1 ? 
ATOM   2056 C CD2 . PHE B 2 66  ? -33.401 -14.423 -0.626  1.000 66.545  0 66  PHE LLL CD2 1 ? 
ATOM   2057 C CE1 . PHE B 2 66  ? -32.828 -16.559 1.013   1.000 66.268  0 66  PHE LLL CE1 1 ? 
ATOM   2058 C CE2 . PHE B 2 66  ? -32.085 -14.784 -0.391  1.000 66.929  0 66  PHE LLL CE2 1 ? 
ATOM   2059 C CZ  . PHE B 2 66  ? -31.802 -15.857 0.420   1.000 69.739  0 66  PHE LLL CZ  1 ? 
ATOM   2060 N N   . SER B 2 67  ? -38.830 -15.990 -1.342  1.000 62.122  0 67  SER LLL N   1 ? 
ATOM   2061 C CA  . SER B 2 67  ? -40.292 -15.784 -1.471  1.000 68.973  0 67  SER LLL CA  1 ? 
ATOM   2062 C C   . SER B 2 67  ? -40.981 -16.250 -0.188  1.000 76.131  0 67  SER LLL C   1 ? 
ATOM   2063 O O   . SER B 2 67  ? -40.406 -17.055 0.558   1.000 64.988  0 67  SER LLL O   1 ? 
ATOM   2064 C CB  . SER B 2 67  ? -40.848 -16.493 -2.680  1.000 68.778  0 67  SER LLL CB  1 ? 
ATOM   2065 O OG  . SER B 2 67  ? -41.453 -17.731 -2.299  1.000 76.716  0 67  SER LLL OG  1 ? 
ATOM   2066 N N   . GLY B 2 68  ? -42.201 -15.767 0.038   1.000 85.331  0 68  GLY LLL N   1 ? 
ATOM   2067 C CA  . GLY B 2 68  ? -43.025 -16.157 1.194   1.000 77.762  0 68  GLY LLL CA  1 ? 
ATOM   2068 C C   . GLY B 2 68  ? -43.977 -17.260 0.823   1.000 69.972  0 68  GLY LLL C   1 ? 
ATOM   2069 O O   . GLY B 2 68  ? -43.644 -18.008 -0.076  1.000 102.178 0 68  GLY LLL O   1 ? 
ATOM   2070 N N   . SER B 2 69  ? -45.135 -17.364 1.457   1.000 67.579  0 69  SER LLL N   1 ? 
ATOM   2071 C CA  . SER B 2 69  ? -46.033 -18.531 1.252   1.000 76.239  0 69  SER LLL CA  1 ? 
ATOM   2072 C C   . SER B 2 69  ? -47.409 -18.348 1.891   1.000 95.076  0 69  SER LLL C   1 ? 
ATOM   2073 O O   . SER B 2 69  ? -48.154 -17.437 1.463   1.000 122.704 0 69  SER LLL O   1 ? 
ATOM   2074 C CB  . SER B 2 69  ? -45.429 -19.752 1.827   1.000 82.031  0 69  SER LLL CB  1 ? 
ATOM   2075 O OG  . SER B 2 69  ? -45.350 -19.621 3.240   1.000 77.618  0 69  SER LLL OG  1 ? 
ATOM   2076 N N   . GLY B 2 70  ? -47.732 -19.205 2.872   1.000 81.252  0 70  GLY LLL N   1 ? 
ATOM   2077 C CA  . GLY B 2 70  ? -49.118 -19.642 3.101   1.000 81.062  0 70  GLY LLL CA  1 ? 
ATOM   2078 C C   . GLY B 2 70  ? -49.681 -19.200 4.427   1.000 77.676  0 70  GLY LLL C   1 ? 
ATOM   2079 O O   . GLY B 2 70  ? -49.375 -18.099 4.894   1.000 82.161  0 70  GLY LLL O   1 ? 
ATOM   2080 N N   . SER B 2 71  ? -50.538 -20.036 5.000   1.000 88.888  0 71  SER LLL N   1 ? 
ATOM   2081 C CA  . SER B 2 71  ? -51.338 -19.679 6.190   1.000 88.752  0 71  SER LLL CA  1 ? 
ATOM   2082 C C   . SER B 2 71  ? -51.770 -20.943 6.921   1.000 84.068  0 71  SER LLL C   1 ? 
ATOM   2083 O O   . SER B 2 71  ? -51.453 -22.050 6.454   1.000 76.733  0 71  SER LLL O   1 ? 
ATOM   2084 C CB  . SER B 2 71  ? -52.509 -18.830 5.790   1.000 99.409  0 71  SER LLL CB  1 ? 
ATOM   2085 O OG  . SER B 2 71  ? -53.326 -19.523 4.860   1.000 105.310 0 71  SER LLL OG  1 ? 
ATOM   2086 N N   . GLY B 2 72  ? -52.449 -20.752 8.050   1.000 86.609  0 72  GLY LLL N   1 ? 
ATOM   2087 C CA  . GLY B 2 72  ? -52.889 -21.836 8.938   1.000 81.818  0 72  GLY LLL CA  1 ? 
ATOM   2088 C C   . GLY B 2 72  ? -51.696 -22.423 9.656   1.000 74.274  0 72  GLY LLL C   1 ? 
ATOM   2089 O O   . GLY B 2 72  ? -51.152 -21.750 10.543  1.000 66.843  0 72  GLY LLL O   1 ? 
ATOM   2090 N N   . THR B 2 73  ? -51.293 -23.628 9.276   1.000 70.404  0 73  THR LLL N   1 ? 
ATOM   2091 C CA  . THR B 2 73  ? -50.214 -24.379 9.963   1.000 74.953  0 73  THR LLL CA  1 ? 
ATOM   2092 C C   . THR B 2 73  ? -49.065 -24.642 8.994   1.000 75.357  0 73  THR LLL C   1 ? 
ATOM   2093 O O   . THR B 2 73  ? -48.038 -25.161 9.438   1.000 78.552  0 73  THR LLL O   1 ? 
ATOM   2094 C CB  . THR B 2 73  ? -50.772 -25.672 10.562  1.000 73.559  0 73  THR LLL CB  1 ? 
ATOM   2095 O OG1 . THR B 2 73  ? -51.285 -26.474 9.503   1.000 78.727  0 73  THR LLL OG1 1 ? 
ATOM   2096 C CG2 . THR B 2 73  ? -51.882 -25.425 11.554  1.000 69.966  0 73  THR LLL CG2 1 ? 
ATOM   2097 N N   . ASP B 2 74  ? -49.226 -24.291 7.721   1.000 80.471  0 74  ASP LLL N   1 ? 
ATOM   2098 C CA  . ASP B 2 74  ? -48.265 -24.674 6.659   1.000 82.531  0 74  ASP LLL CA  1 ? 
ATOM   2099 C C   . ASP B 2 74  ? -47.661 -23.398 6.075   1.000 74.460  0 74  ASP LLL C   1 ? 
ATOM   2100 O O   . ASP B 2 74  ? -48.424 -22.614 5.480   1.000 76.480  0 74  ASP LLL O   1 ? 
ATOM   2101 C CB  . ASP B 2 74  ? -48.955 -25.617 5.677   1.000 89.520  0 74  ASP LLL CB  1 ? 
ATOM   2102 C CG  . ASP B 2 74  ? -49.443 -26.870 6.389   1.000 101.749 0 74  ASP LLL CG  1 ? 
ATOM   2103 O OD1 . ASP B 2 74  ? -48.689 -27.388 7.244   1.000 93.833  0 74  ASP LLL OD1 1 ? 
ATOM   2104 O OD2 . ASP B 2 74  ? -50.584 -27.295 6.121   1.000 119.631 0 74  ASP LLL OD2 1 ? 
ATOM   2105 N N   . PHE B 2 75  ? -46.351 -23.197 6.290   1.000 62.627  0 75  PHE LLL N   1 ? 
ATOM   2106 C CA  . PHE B 2 75  ? -45.552 -22.042 5.791   1.000 61.083  0 75  PHE LLL CA  1 ? 
ATOM   2107 C C   . PHE B 2 75  ? -44.327 -22.561 5.033   1.000 57.398  0 75  PHE LLL C   1 ? 
ATOM   2108 O O   . PHE B 2 75  ? -43.825 -23.630 5.366   1.000 54.079  0 75  PHE LLL O   1 ? 
ATOM   2109 C CB  . PHE B 2 75  ? -45.208 -21.108 6.957   1.000 61.805  0 75  PHE LLL CB  1 ? 
ATOM   2110 C CG  . PHE B 2 75  ? -46.445 -20.645 7.680   1.000 62.509  0 75  PHE LLL CG  1 ? 
ATOM   2111 C CD1 . PHE B 2 75  ? -47.147 -19.539 7.239   1.000 58.494  0 75  PHE LLL CD1 1 ? 
ATOM   2112 C CD2 . PHE B 2 75  ? -46.947 -21.365 8.751   1.000 66.817  0 75  PHE LLL CD2 1 ? 
ATOM   2113 C CE1 . PHE B 2 75  ? -48.322 -19.152 7.862   1.000 61.581  0 75  PHE LLL CE1 1 ? 
ATOM   2114 C CE2 . PHE B 2 75  ? -48.129 -20.984 9.362   1.000 69.015  0 75  PHE LLL CE2 1 ? 
ATOM   2115 C CZ  . PHE B 2 75  ? -48.820 -19.885 8.909   1.000 67.623  0 75  PHE LLL CZ  1 ? 
ATOM   2116 N N   . THR B 2 76  ? -43.841 -21.802 4.051   1.000 63.431  0 76  THR LLL N   1 ? 
ATOM   2117 C CA  . THR B 2 76  ? -42.747 -22.228 3.136   1.000 70.181  0 76  THR LLL CA  1 ? 
ATOM   2118 C C   . THR B 2 76  ? -41.984 -21.009 2.618   1.000 61.739  0 76  THR LLL C   1 ? 
ATOM   2119 C CB  . THR B 2 76  ? -43.285 -23.034 1.943   1.000 75.988  0 76  THR LLL CB  1 ? 
ATOM   2120 O OG1 . THR B 2 76  ? -44.577 -22.539 1.605   1.000 88.661  0 76  THR LLL OG1 1 ? 
ATOM   2121 C CG2 . THR B 2 76  ? -43.425 -24.514 2.215   1.000 79.126  0 76  THR LLL CG2 1 ? 
ATOM   2122 N N   . VAL B 2 77  ? -40.696 -20.925 2.950   1.000 63.235  0 77  VAL LLL N   1 ? 
ATOM   2123 C CA  . VAL B 2 77  ? -39.749 -19.970 2.303   1.000 68.902  0 77  VAL LLL CA  1 ? 
ATOM   2124 C C   . VAL B 2 77  ? -39.068 -20.705 1.151   1.000 69.756  0 77  VAL LLL C   1 ? 
ATOM   2125 O O   . VAL B 2 77  ? -38.748 -21.884 1.313   1.000 74.325  0 77  VAL LLL O   1 ? 
ATOM   2126 C CB  . VAL B 2 77  ? -38.729 -19.365 3.286   1.000 78.368  0 77  VAL LLL CB  1 ? 
ATOM   2127 C CG1 . VAL B 2 77  ? -37.794 -20.406 3.887   1.000 82.187  0 77  VAL LLL CG1 1 ? 
ATOM   2128 C CG2 . VAL B 2 77  ? -37.928 -18.243 2.642   1.000 77.360  0 77  VAL LLL CG2 1 ? 
ATOM   2129 N N   . ASN B 2 78  ? -38.940 -20.028 0.011   1.000 70.480  0 78  ASN LLL N   1 ? 
ATOM   2130 C CA  . ASN B 2 78  ? -38.401 -20.595 -1.246  1.000 66.907  0 78  ASN LLL CA  1 ? 
ATOM   2131 C C   . ASN B 2 78  ? -37.234 -19.727 -1.690  1.000 71.523  0 78  ASN LLL C   1 ? 
ATOM   2132 O O   . ASN B 2 78  ? -37.354 -18.497 -1.677  1.000 62.198  0 78  ASN LLL O   1 ? 
ATOM   2133 C CB  . ASN B 2 78  ? -39.437 -20.644 -2.363  1.000 66.829  0 78  ASN LLL CB  1 ? 
ATOM   2134 C CG  . ASN B 2 78  ? -40.658 -21.452 -1.993  1.000 76.989  0 78  ASN LLL CG  1 ? 
ATOM   2135 O OD1 . ASN B 2 78  ? -41.375 -21.117 -1.051  1.000 79.592  0 78  ASN LLL OD1 1 ? 
ATOM   2136 N ND2 . ASN B 2 78  ? -40.909 -22.514 -2.744  1.000 85.718  0 78  ASN LLL ND2 1 ? 
ATOM   2137 N N   . ILE B 2 79  ? -36.148 -20.371 -2.086  1.000 72.961  0 79  ILE LLL N   1 ? 
ATOM   2138 C CA  . ILE B 2 79  ? -34.970 -19.685 -2.665  1.000 69.879  0 79  ILE LLL CA  1 ? 
ATOM   2139 C C   . ILE B 2 79  ? -34.925 -20.131 -4.124  1.000 64.629  0 79  ILE LLL C   1 ? 
ATOM   2140 O O   . ILE B 2 79  ? -34.768 -21.317 -4.347  1.000 59.061  0 79  ILE LLL O   1 ? 
ATOM   2141 C CB  . ILE B 2 79  ? -33.693 -20.023 -1.864  1.000 71.136  0 79  ILE LLL CB  1 ? 
ATOM   2142 C CG1 . ILE B 2 79  ? -34.014 -20.283 -0.389  1.000 70.281  0 79  ILE LLL CG1 1 ? 
ATOM   2143 C CG2 . ILE B 2 79  ? -32.647 -18.933 -2.048  1.000 71.518  0 79  ILE LLL CG2 1 ? 
ATOM   2144 C CD1 . ILE B 2 79  ? -32.813 -20.356 0.520   1.000 71.113  0 79  ILE LLL CD1 1 ? 
ATOM   2145 N N   . HIS B 2 80  ? -35.117 -19.206 -5.059  1.000 66.396  0 80  HIS LLL N   1 ? 
ATOM   2146 C CA  . HIS B 2 80  ? -35.181 -19.484 -6.512  1.000 70.180  0 80  HIS LLL CA  1 ? 
ATOM   2147 C C   . HIS B 2 80  ? -34.566 -18.319 -7.273  1.000 66.755  0 80  HIS LLL C   1 ? 
ATOM   2148 O O   . HIS B 2 80  ? -35.226 -17.311 -7.495  1.000 68.506  0 80  HIS LLL O   1 ? 
ATOM   2149 C CB  . HIS B 2 80  ? -36.627 -19.740 -6.946  1.000 82.077  0 80  HIS LLL CB  1 ? 
ATOM   2150 C CG  . HIS B 2 80  ? -36.757 -20.019 -8.408  1.000 100.535 0 80  HIS LLL CG  1 ? 
ATOM   2151 N ND1 . HIS B 2 80  ? -36.282 -21.189 -8.990  1.000 98.166  0 80  HIS LLL ND1 1 ? 
ATOM   2152 C CD2 . HIS B 2 80  ? -37.291 -19.285 -9.409  1.000 107.787 0 80  HIS LLL CD2 1 ? 
ATOM   2153 C CE1 . HIS B 2 80  ? -36.526 -21.167 -10.281 1.000 104.764 0 80  HIS LLL CE1 1 ? 
ATOM   2154 N NE2 . HIS B 2 80  ? -37.141 -20.007 -10.563 1.000 120.538 0 80  HIS LLL NE2 1 ? 
ATOM   2155 N N   . PRO B 2 81  ? -33.296 -18.421 -7.714  1.000 66.129  0 81  PRO LLL N   1 ? 
ATOM   2156 C CA  . PRO B 2 81  ? -32.459 -19.588 -7.441  1.000 67.947  0 81  PRO LLL CA  1 ? 
ATOM   2157 C C   . PRO B 2 81  ? -31.683 -19.462 -6.124  1.000 72.473  0 81  PRO LLL C   1 ? 
ATOM   2158 O O   . PRO B 2 81  ? -31.718 -18.423 -5.488  1.000 82.261  0 81  PRO LLL O   1 ? 
ATOM   2159 C CB  . PRO B 2 81  ? -31.487 -19.575 -8.629  1.000 66.094  0 81  PRO LLL CB  1 ? 
ATOM   2160 C CG  . PRO B 2 81  ? -31.299 -18.093 -8.921  1.000 67.145  0 81  PRO LLL CG  1 ? 
ATOM   2161 C CD  . PRO B 2 81  ? -32.601 -17.415 -8.536  1.000 65.031  0 81  PRO LLL CD  1 ? 
ATOM   2162 N N   . VAL B 2 82  ? -30.955 -20.514 -5.769  1.000 73.490  0 82  VAL LLL N   1 ? 
ATOM   2163 C CA  . VAL B 2 82  ? -29.971 -20.493 -4.651  1.000 68.009  0 82  VAL LLL CA  1 ? 
ATOM   2164 C C   . VAL B 2 82  ? -28.659 -19.910 -5.179  1.000 70.471  0 82  VAL LLL C   1 ? 
ATOM   2165 O O   . VAL B 2 82  ? -28.316 -20.184 -6.344  1.000 67.113  0 82  VAL LLL O   1 ? 
ATOM   2166 C CB  . VAL B 2 82  ? -29.783 -21.901 -4.063  1.000 62.208  0 82  VAL LLL CB  1 ? 
ATOM   2167 C CG1 . VAL B 2 82  ? -28.463 -22.043 -3.324  1.000 60.925  0 82  VAL LLL CG1 1 ? 
ATOM   2168 C CG2 . VAL B 2 82  ? -30.954 -22.264 -3.172  1.000 61.952  0 82  VAL LLL CG2 1 ? 
ATOM   2169 N N   . GLU B 2 83  ? -27.969 -19.122 -4.351  1.000 76.813  0 83  GLU LLL N   1 ? 
ATOM   2170 C CA  . GLU B 2 83  ? -26.624 -18.563 -4.652  1.000 83.206  0 83  GLU LLL CA  1 ? 
ATOM   2171 C C   . GLU B 2 83  ? -25.656 -18.983 -3.539  1.000 79.978  0 83  GLU LLL C   1 ? 
ATOM   2172 O O   . GLU B 2 83  ? -26.144 -19.459 -2.502  1.000 80.467  0 83  GLU LLL O   1 ? 
ATOM   2173 C CB  . GLU B 2 83  ? -26.740 -17.052 -4.845  1.000 86.290  0 83  GLU LLL CB  1 ? 
ATOM   2174 C CG  . GLU B 2 83  ? -27.260 -16.663 -6.220  1.000 93.825  0 83  GLU LLL CG  1 ? 
ATOM   2175 C CD  . GLU B 2 83  ? -26.871 -15.254 -6.646  1.000 118.687 0 83  GLU LLL CD  1 ? 
ATOM   2176 O OE1 . GLU B 2 83  ? -27.604 -14.297 -6.297  1.000 131.131 0 83  GLU LLL OE1 1 ? 
ATOM   2177 O OE2 . GLU B 2 83  ? -25.818 -15.108 -7.306  1.000 139.199 0 83  GLU LLL OE2 1 ? 
ATOM   2178 N N   . GLU B 2 84  ? -24.338 -18.863 -3.755  1.000 83.792  0 84  GLU LLL N   1 ? 
ATOM   2179 C CA  . GLU B 2 84  ? -23.305 -19.355 -2.795  1.000 81.858  0 84  GLU LLL CA  1 ? 
ATOM   2180 C C   . GLU B 2 84  ? -23.469 -18.566 -1.486  1.000 80.604  0 84  GLU LLL C   1 ? 
ATOM   2181 O O   . GLU B 2 84  ? -23.323 -19.156 -0.402  1.000 79.369  0 84  GLU LLL O   1 ? 
ATOM   2182 C CB  . GLU B 2 84  ? -21.889 -19.294 -3.389  1.000 70.752  0 84  GLU LLL CB  1 ? 
ATOM   2183 N N   . GLU B 2 85  ? -23.861 -17.296 -1.588  1.000 81.792  0 85  GLU LLL N   1 ? 
ATOM   2184 C CA  . GLU B 2 85  ? -24.069 -16.389 -0.428  1.000 84.263  0 85  GLU LLL CA  1 ? 
ATOM   2185 C C   . GLU B 2 85  ? -25.227 -16.863 0.465   1.000 81.448  0 85  GLU LLL C   1 ? 
ATOM   2186 O O   . GLU B 2 85  ? -25.494 -16.172 1.458   1.000 88.830  0 85  GLU LLL O   1 ? 
ATOM   2187 C CB  . GLU B 2 85  ? -24.325 -14.960 -0.922  1.000 89.475  0 85  GLU LLL CB  1 ? 
ATOM   2188 C CG  . GLU B 2 85  ? -25.498 -14.833 -1.888  1.000 95.669  0 85  GLU LLL CG  1 ? 
ATOM   2189 C CD  . GLU B 2 85  ? -25.140 -14.203 -3.228  1.000 98.491  0 85  GLU LLL CD  1 ? 
ATOM   2190 O OE1 . GLU B 2 85  ? -24.149 -14.668 -3.849  1.000 93.723  0 85  GLU LLL OE1 1 ? 
ATOM   2191 O OE2 . GLU B 2 85  ? -25.847 -13.247 -3.648  1.000 93.479  0 85  GLU LLL OE2 1 ? 
ATOM   2192 N N   . ASP B 2 86  ? -25.896 -17.977 0.154   1.000 74.048  0 86  ASP LLL N   1 ? 
ATOM   2193 C CA  . ASP B 2 86  ? -27.155 -18.367 0.844   1.000 68.677  0 86  ASP LLL CA  1 ? 
ATOM   2194 C C   . ASP B 2 86  ? -26.878 -19.401 1.937   1.000 64.704  0 86  ASP LLL C   1 ? 
ATOM   2195 O O   . ASP B 2 86  ? -27.843 -19.832 2.600   1.000 61.772  0 86  ASP LLL O   1 ? 
ATOM   2196 C CB  . ASP B 2 86  ? -28.190 -18.868 -0.163  1.000 68.703  0 86  ASP LLL CB  1 ? 
ATOM   2197 C CG  . ASP B 2 86  ? -28.726 -17.773 -1.069  1.000 74.905  0 86  ASP LLL CG  1 ? 
ATOM   2198 O OD1 . ASP B 2 86  ? -28.537 -16.561 -0.738  1.000 74.765  0 86  ASP LLL OD1 1 ? 
ATOM   2199 O OD2 . ASP B 2 86  ? -29.328 -18.136 -2.101  1.000 81.656  0 86  ASP LLL OD2 1 ? 
ATOM   2200 N N   . ALA B 2 87  ? -25.620 -19.801 2.111   1.000 67.941  0 87  ALA LLL N   1 ? 
ATOM   2201 C CA  . ALA B 2 87  ? -25.220 -20.818 3.105   1.000 66.412  0 87  ALA LLL CA  1 ? 
ATOM   2202 C C   . ALA B 2 87  ? -25.470 -20.202 4.472   1.000 67.171  0 87  ALA LLL C   1 ? 
ATOM   2203 O O   . ALA B 2 87  ? -24.772 -19.221 4.801   1.000 69.058  0 87  ALA LLL O   1 ? 
ATOM   2204 C CB  . ALA B 2 87  ? -23.773 -21.212 2.930   1.000 70.574  0 87  ALA LLL CB  1 ? 
ATOM   2205 N N   . ALA B 2 88  ? -26.456 -20.716 5.203   1.000 62.818  0 88  ALA LLL N   1 ? 
ATOM   2206 C CA  . ALA B 2 88  ? -26.877 -20.147 6.499   1.000 62.007  0 88  ALA LLL CA  1 ? 
ATOM   2207 C C   . ALA B 2 88  ? -27.901 -21.065 7.143   1.000 61.579  0 88  ALA LLL C   1 ? 
ATOM   2208 O O   . ALA B 2 88  ? -28.381 -21.981 6.467   1.000 68.980  0 88  ALA LLL O   1 ? 
ATOM   2209 C CB  . ALA B 2 88  ? -27.450 -18.769 6.291   1.000 58.265  0 88  ALA LLL CB  1 ? 
ATOM   2210 N N   . THR B 2 89  ? -28.229 -20.808 8.403   1.000 61.874  0 89  THR LLL N   1 ? 
ATOM   2211 C CA  . THR B 2 89  ? -29.317 -21.529 9.093   1.000 62.716  0 89  THR LLL CA  1 ? 
ATOM   2212 C C   . THR B 2 89  ? -30.576 -20.676 9.006   1.000 56.673  0 89  THR LLL C   1 ? 
ATOM   2213 O O   . THR B 2 89  ? -30.555 -19.510 9.388   1.000 58.958  0 89  THR LLL O   1 ? 
ATOM   2214 C CB  . THR B 2 89  ? -28.912 -21.941 10.508  1.000 65.738  0 89  THR LLL CB  1 ? 
ATOM   2215 O OG1 . THR B 2 89  ? -27.564 -22.406 10.429  1.000 69.778  0 89  THR LLL OG1 1 ? 
ATOM   2216 C CG2 . THR B 2 89  ? -29.819 -23.013 11.075  1.000 63.175  0 89  THR LLL CG2 1 ? 
ATOM   2217 N N   . TYR B 2 90  ? -31.640 -21.256 8.488   1.000 53.606  0 90  TYR LLL N   1 ? 
ATOM   2218 C CA  . TYR B 2 90  ? -32.909 -20.532 8.290   1.000 50.624  0 90  TYR LLL CA  1 ? 
ATOM   2219 C C   . TYR B 2 90  ? -33.806 -20.904 9.453   1.000 53.004  0 90  TYR LLL C   1 ? 
ATOM   2220 O O   . TYR B 2 90  ? -33.977 -22.096 9.725   1.000 53.822  0 90  TYR LLL O   1 ? 
ATOM   2221 C CB  . TYR B 2 90  ? -33.473 -20.804 6.900   1.000 48.186  0 90  TYR LLL CB  1 ? 
ATOM   2222 C CG  . TYR B 2 90  ? -32.613 -20.198 5.823   1.000 49.917  0 90  TYR LLL CG  1 ? 
ATOM   2223 C CD1 . TYR B 2 90  ? -31.487 -20.845 5.350   1.000 52.844  0 90  TYR LLL CD1 1 ? 
ATOM   2224 C CD2 . TYR B 2 90  ? -32.882 -18.936 5.327   1.000 52.999  0 90  TYR LLL CD2 1 ? 
ATOM   2225 C CE1 . TYR B 2 90  ? -30.677 -20.268 4.385   1.000 55.736  0 90  TYR LLL CE1 1 ? 
ATOM   2226 C CE2 . TYR B 2 90  ? -32.072 -18.334 4.380   1.000 52.912  0 90  TYR LLL CE2 1 ? 
ATOM   2227 C CZ  . TYR B 2 90  ? -30.968 -19.008 3.906   1.000 53.344  0 90  TYR LLL CZ  1 ? 
ATOM   2228 O OH  . TYR B 2 90  ? -30.177 -18.439 2.963   1.000 59.473  0 90  TYR LLL OH  1 ? 
ATOM   2229 N N   . TYR B 2 91  ? -34.319 -19.881 10.133  1.000 56.050  0 91  TYR LLL N   1 ? 
ATOM   2230 C CA  . TYR B 2 91  ? -35.195 -20.025 11.314  1.000 53.087  0 91  TYR LLL CA  1 ? 
ATOM   2231 C C   . TYR B 2 91  ? -36.552 -19.455 10.974  1.000 54.363  0 91  TYR LLL C   1 ? 
ATOM   2232 O O   . TYR B 2 91  ? -36.599 -18.368 10.388  1.000 52.631  0 91  TYR LLL O   1 ? 
ATOM   2233 C CB  . TYR B 2 91  ? -34.646 -19.295 12.530  1.000 58.883  0 91  TYR LLL CB  1 ? 
ATOM   2234 C CG  . TYR B 2 91  ? -33.377 -19.891 13.069  1.000 64.201  0 91  TYR LLL CG  1 ? 
ATOM   2235 C CD1 . TYR B 2 91  ? -32.158 -19.458 12.579  1.000 68.004  0 91  TYR LLL CD1 1 ? 
ATOM   2236 C CD2 . TYR B 2 91  ? -33.389 -20.893 14.034  1.000 60.995  0 91  TYR LLL CD2 1 ? 
ATOM   2237 C CE1 . TYR B 2 91  ? -30.970 -19.997 13.039  1.000 72.894  0 91  TYR LLL CE1 1 ? 
ATOM   2238 C CE2 . TYR B 2 91  ? -32.208 -21.429 14.514  1.000 62.507  0 91  TYR LLL CE2 1 ? 
ATOM   2239 C CZ  . TYR B 2 91  ? -30.997 -20.982 14.008  1.000 67.539  0 91  TYR LLL CZ  1 ? 
ATOM   2240 O OH  . TYR B 2 91  ? -29.798 -21.462 14.433  1.000 71.138  0 91  TYR LLL OH  1 ? 
ATOM   2241 N N   . CYS B 2 92  ? -37.593 -20.161 11.405  1.000 58.835  0 92  CYS LLL N   1 ? 
ATOM   2242 C CA  . CYS B 2 92  ? -39.008 -19.762 11.263  1.000 60.126  0 92  CYS LLL CA  1 ? 
ATOM   2243 C C   . CYS B 2 92  ? -39.403 -19.284 12.657  1.000 58.263  0 92  CYS LLL C   1 ? 
ATOM   2244 O O   . CYS B 2 92  ? -38.725 -19.701 13.595  1.000 70.875  0 92  CYS LLL O   1 ? 
ATOM   2245 C CB  . CYS B 2 92  ? -39.830 -20.896 10.654  1.000 64.332  0 92  CYS LLL CB  1 ? 
ATOM   2246 S SG  . CYS B 2 92  ? -40.286 -22.264 11.749  1.000 76.886  0 92  CYS LLL SG  1 ? 
ATOM   2247 N N   . GLN B 2 93  ? -40.343 -18.351 12.782  1.000 55.671  0 93  GLN LLL N   1 ? 
ATOM   2248 C CA  . GLN B 2 93  ? -40.714 -17.738 14.086  1.000 55.105  0 93  GLN LLL CA  1 ? 
ATOM   2249 C C   . GLN B 2 93  ? -42.154 -17.235 14.041  1.000 50.308  0 93  GLN LLL C   1 ? 
ATOM   2250 O O   . GLN B 2 93  ? -42.505 -16.621 13.027  1.000 46.070  0 93  GLN LLL O   1 ? 
ATOM   2251 C CB  . GLN B 2 93  ? -39.779 -16.568 14.368  1.000 58.327  0 93  GLN LLL CB  1 ? 
ATOM   2252 C CG  . GLN B 2 93  ? -40.076 -15.819 15.660  1.000 62.863  0 93  GLN LLL CG  1 ? 
ATOM   2253 C CD  . GLN B 2 93  ? -40.650 -14.434 15.463  1.000 64.735  0 93  GLN LLL CD  1 ? 
ATOM   2254 O OE1 . GLN B 2 93  ? -40.395 -13.757 14.469  1.000 64.200  0 93  GLN LLL OE1 1 ? 
ATOM   2255 N NE2 . GLN B 2 93  ? -41.407 -13.980 16.446  1.000 71.818  0 93  GLN LLL NE2 1 ? 
ATOM   2256 N N   . GLN B 2 94  ? -42.928 -17.437 15.111  1.000 47.056  0 94  GLN LLL N   1 ? 
ATOM   2257 C CA  . GLN B 2 94  ? -44.329 -16.939 15.207  1.000 52.511  0 94  GLN LLL CA  1 ? 
ATOM   2258 C C   . GLN B 2 94  ? -44.418 -15.793 16.227  1.000 57.398  0 94  GLN LLL C   1 ? 
ATOM   2259 O O   . GLN B 2 94  ? -43.558 -15.688 17.129  1.000 52.812  0 94  GLN LLL O   1 ? 
ATOM   2260 C CB  . GLN B 2 94  ? -45.303 -18.060 15.564  1.000 53.752  0 94  GLN LLL CB  1 ? 
ATOM   2261 C CG  . GLN B 2 94  ? -45.044 -18.681 16.934  1.000 55.901  0 94  GLN LLL CG  1 ? 
ATOM   2262 C CD  . GLN B 2 94  ? -45.949 -18.122 18.002  1.000 55.543  0 94  GLN LLL CD  1 ? 
ATOM   2263 O OE1 . GLN B 2 94  ? -46.993 -17.548 17.703  1.000 63.360  0 94  GLN LLL OE1 1 ? 
ATOM   2264 N NE2 . GLN B 2 94  ? -45.568 -18.313 19.256  1.000 53.554  0 94  GLN LLL NE2 1 ? 
ATOM   2265 N N   . SER B 2 95  ? -45.420 -14.937 16.055  1.000 59.400  0 95  SER LLL N   1 ? 
ATOM   2266 C CA  . SER B 2 95  ? -45.752 -13.825 16.976  1.000 67.463  0 95  SER LLL CA  1 ? 
ATOM   2267 C C   . SER B 2 95  ? -47.266 -13.774 17.157  1.000 67.123  0 95  SER LLL C   1 ? 
ATOM   2268 O O   . SER B 2 95  ? -47.775 -12.731 17.597  1.000 85.785  0 95  SER LLL O   1 ? 
ATOM   2269 C CB  . SER B 2 95  ? -45.207 -12.509 16.464  1.000 69.524  0 95  SER LLL CB  1 ? 
ATOM   2270 O OG  . SER B 2 95  ? -43.789 -12.550 16.350  1.000 68.661  0 95  SER LLL OG  1 ? 
ATOM   2271 N N   . THR B 2 96  ? -47.941 -14.869 16.820  1.000 66.570  0 96  THR LLL N   1 ? 
ATOM   2272 C CA  . THR B 2 96  ? -49.399 -15.065 16.980  1.000 68.014  0 96  THR LLL CA  1 ? 
ATOM   2273 C C   . THR B 2 96  ? -49.713 -15.013 18.470  1.000 67.036  0 96  THR LLL C   1 ? 
ATOM   2274 O O   . THR B 2 96  ? -50.585 -14.219 18.865  1.000 69.811  0 96  THR LLL O   1 ? 
ATOM   2275 C CB  . THR B 2 96  ? -49.817 -16.399 16.353  1.000 71.078  0 96  THR LLL CB  1 ? 
ATOM   2276 O OG1 . THR B 2 96  ? -49.330 -16.370 15.011  1.000 76.561  0 96  THR LLL OG1 1 ? 
ATOM   2277 C CG2 . THR B 2 96  ? -51.311 -16.636 16.392  1.000 74.040  0 96  THR LLL CG2 1 ? 
ATOM   2278 N N   . GLU B 2 97  ? -48.979 -15.812 19.248  1.000 70.377  0 97  GLU LLL N   1 ? 
ATOM   2279 C CA  . GLU B 2 97  ? -49.163 -15.954 20.710  1.000 73.778  0 97  GLU LLL CA  1 ? 
ATOM   2280 C C   . GLU B 2 97  ? -47.829 -15.756 21.421  1.000 67.260  0 97  GLU LLL C   1 ? 
ATOM   2281 O O   . GLU B 2 97  ? -46.809 -16.229 20.922  1.000 61.870  0 97  GLU LLL O   1 ? 
ATOM   2282 C CB  . GLU B 2 97  ? -49.793 -17.307 21.031  1.000 79.688  0 97  GLU LLL CB  1 ? 
ATOM   2283 C CG  . GLU B 2 97  ? -51.305 -17.260 20.928  1.000 88.854  0 97  GLU LLL CG  1 ? 
ATOM   2284 C CD  . GLU B 2 97  ? -52.002 -18.598 21.082  1.000 105.597 0 97  GLU LLL CD  1 ? 
ATOM   2285 O OE1 . GLU B 2 97  ? -51.358 -19.559 21.594  1.000 103.005 0 97  GLU LLL OE1 1 ? 
ATOM   2286 O OE2 . GLU B 2 97  ? -53.192 -18.680 20.689  1.000 117.818 0 97  GLU LLL OE2 1 ? 
ATOM   2287 N N   . ASP B 2 98  ? -47.862 -15.057 22.554  1.000 74.786  0 98  ASP LLL N   1 ? 
ATOM   2288 C CA  . ASP B 2 98  ? -46.742 -15.021 23.529  1.000 79.237  0 98  ASP LLL CA  1 ? 
ATOM   2289 C C   . ASP B 2 98  ? -46.742 -16.366 24.251  1.000 77.480  0 98  ASP LLL C   1 ? 
ATOM   2290 O O   . ASP B 2 98  ? -47.765 -16.824 24.746  1.000 88.524  0 98  ASP LLL O   1 ? 
ATOM   2291 C CB  . ASP B 2 98  ? -46.828 -13.790 24.436  1.000 83.618  0 98  ASP LLL CB  1 ? 
ATOM   2292 C CG  . ASP B 2 98  ? -46.619 -12.480 23.688  1.000 93.241  0 98  ASP LLL CG  1 ? 
ATOM   2293 O OD1 . ASP B 2 98  ? -45.742 -12.442 22.768  1.000 99.712  0 98  ASP LLL OD1 1 ? 
ATOM   2294 O OD2 . ASP B 2 98  ? -47.332 -11.502 24.020  1.000 92.189  0 98  ASP LLL OD2 1 ? 
ATOM   2295 N N   . PRO B 2 99  ? -45.603 -17.081 24.299  1.000 78.515  0 99  PRO LLL N   1 ? 
ATOM   2296 C CA  . PRO B 2 99  ? -44.302 -16.532 23.926  1.000 79.977  0 99  PRO LLL CA  1 ? 
ATOM   2297 C C   . PRO B 2 99  ? -43.960 -16.649 22.433  1.000 78.872  0 99  PRO LLL C   1 ? 
ATOM   2298 O O   . PRO B 2 99  ? -44.225 -17.684 21.835  1.000 81.585  0 99  PRO LLL O   1 ? 
ATOM   2299 C CB  . PRO B 2 99  ? -43.340 -17.389 24.756  1.000 80.094  0 99  PRO LLL CB  1 ? 
ATOM   2300 C CG  . PRO B 2 99  ? -44.038 -18.734 24.887  1.000 82.968  0 99  PRO LLL CG  1 ? 
ATOM   2301 C CD  . PRO B 2 99  ? -45.522 -18.490 24.693  1.000 80.567  0 99  PRO LLL CD  1 ? 
ATOM   2302 N N   . ARG B 2 100 ? -43.391 -15.579 21.869  1.000 81.573  0 100 ARG LLL N   1 ? 
ATOM   2303 C CA  . ARG B 2 100 ? -42.759 -15.611 20.527  1.000 75.621  0 100 ARG LLL CA  1 ? 
ATOM   2304 C C   . ARG B 2 100 ? -41.830 -16.825 20.522  1.000 62.816  0 100 ARG LLL C   1 ? 
ATOM   2305 O O   . ARG B 2 100 ? -41.030 -16.970 21.438  1.000 65.825  0 100 ARG LLL O   1 ? 
ATOM   2306 C CB  . ARG B 2 100 ? -42.026 -14.303 20.221  1.000 74.407  0 100 ARG LLL CB  1 ? 
ATOM   2307 C CG  . ARG B 2 100 ? -42.930 -13.092 20.052  1.000 77.865  0 100 ARG LLL CG  1 ? 
ATOM   2308 C CD  . ARG B 2 100 ? -42.065 -11.932 19.600  1.000 85.869  0 100 ARG LLL CD  1 ? 
ATOM   2309 N NE  . ARG B 2 100 ? -42.803 -10.725 19.248  1.000 98.627  0 100 ARG LLL NE  1 ? 
ATOM   2310 C CZ  . ARG B 2 100 ? -43.236 -9.794  20.104  1.000 108.990 0 100 ARG LLL CZ  1 ? 
ATOM   2311 N NH1 . ARG B 2 100 ? -43.045 -9.923  21.406  1.000 110.431 0 100 ARG LLL NH1 1 ? 
ATOM   2312 N NH2 . ARG B 2 100 ? -43.882 -8.733  19.650  1.000 118.773 0 100 ARG LLL NH2 1 ? 
ATOM   2313 N N   . THR B 2 101 ? -42.016 -17.727 19.578  1.000 57.439  0 101 THR LLL N   1 ? 
ATOM   2314 C CA  . THR B 2 101 ? -41.240 -18.977 19.510  1.000 56.138  0 101 THR LLL CA  1 ? 
ATOM   2315 C C   . THR B 2 101 ? -40.590 -19.030 18.139  1.000 53.214  0 101 THR LLL C   1 ? 
ATOM   2316 O O   . THR B 2 101 ? -41.142 -18.454 17.191  1.000 49.391  0 101 THR LLL O   1 ? 
ATOM   2317 C CB  . THR B 2 101 ? -42.096 -20.220 19.798  1.000 55.992  0 101 THR LLL CB  1 ? 
ATOM   2318 O OG1 . THR B 2 101 ? -43.368 -20.088 19.159  1.000 57.893  0 101 THR LLL OG1 1 ? 
ATOM   2319 C CG2 . THR B 2 101 ? -42.285 -20.459 21.279  1.000 52.896  0 101 THR LLL CG2 1 ? 
ATOM   2320 N N   . PHE B 2 102 ? -39.453 -19.705 18.087  1.000 56.286  0 102 PHE LLL N   1 ? 
ATOM   2321 C CA  . PHE B 2 102 ? -38.665 -19.981 16.870  1.000 56.862  0 102 PHE LLL CA  1 ? 
ATOM   2322 C C   . PHE B 2 102 ? -38.762 -21.466 16.563  1.000 59.380  0 102 PHE LLL C   1 ? 
ATOM   2323 O O   . PHE B 2 102 ? -38.808 -22.269 17.504  1.000 55.774  0 102 PHE LLL O   1 ? 
ATOM   2324 C CB  . PHE B 2 102 ? -37.197 -19.631 17.090  1.000 54.800  0 102 PHE LLL CB  1 ? 
ATOM   2325 C CG  . PHE B 2 102 ? -36.903 -18.161 17.060  1.000 60.151  0 102 PHE LLL CG  1 ? 
ATOM   2326 C CD1 . PHE B 2 102 ? -37.023 -17.384 18.202  1.000 63.008  0 102 PHE LLL CD1 1 ? 
ATOM   2327 C CD2 . PHE B 2 102 ? -36.525 -17.552 15.875  1.000 66.158  0 102 PHE LLL CD2 1 ? 
ATOM   2328 C CE1 . PHE B 2 102 ? -36.767 -16.022 18.158  1.000 65.218  0 102 PHE LLL CE1 1 ? 
ATOM   2329 C CE2 . PHE B 2 102 ? -36.275 -16.188 15.832  1.000 69.855  0 102 PHE LLL CE2 1 ? 
ATOM   2330 C CZ  . PHE B 2 102 ? -36.389 -15.428 16.974  1.000 67.442  0 102 PHE LLL CZ  1 ? 
ATOM   2331 N N   . GLY B 2 103 ? -38.788 -21.793 15.276  1.000 65.520  0 103 GLY LLL N   1 ? 
ATOM   2332 C CA  . GLY B 2 103 ? -38.489 -23.143 14.788  1.000 64.574  0 103 GLY LLL CA  1 ? 
ATOM   2333 C C   . GLY B 2 103 ? -37.067 -23.516 15.140  1.000 65.207  0 103 GLY LLL C   1 ? 
ATOM   2334 O O   . GLY B 2 103 ? -36.256 -22.591 15.444  1.000 58.668  0 103 GLY LLL O   1 ? 
ATOM   2335 N N   . GLY B 2 104 ? -36.787 -24.822 15.065  1.000 62.850  0 104 GLY LLL N   1 ? 
ATOM   2336 C CA  . GLY B 2 104 ? -35.491 -25.457 15.375  1.000 57.878  0 104 GLY LLL CA  1 ? 
ATOM   2337 C C   . GLY B 2 104 ? -34.362 -25.031 14.454  1.000 57.763  0 104 GLY LLL C   1 ? 
ATOM   2338 O O   . GLY B 2 104 ? -33.233 -25.372 14.772  1.000 61.810  0 104 GLY LLL O   1 ? 
ATOM   2339 N N   . GLY B 2 105 ? -34.633 -24.313 13.362  1.000 67.563  0 105 GLY LLL N   1 ? 
ATOM   2340 C CA  . GLY B 2 105 ? -33.612 -23.922 12.365  1.000 73.975  0 105 GLY LLL CA  1 ? 
ATOM   2341 C C   . GLY B 2 105 ? -33.368 -24.997 11.300  1.000 78.218  0 105 GLY LLL C   1 ? 
ATOM   2342 O O   . GLY B 2 105 ? -33.477 -26.200 11.614  1.000 75.522  0 105 GLY LLL O   1 ? 
ATOM   2343 N N   . THR B 2 106 ? -33.038 -24.588 10.071  1.000 75.674  0 106 THR LLL N   1 ? 
ATOM   2344 C CA  . THR B 2 106 ? -32.663 -25.500 8.959   1.000 77.685  0 106 THR LLL CA  1 ? 
ATOM   2345 C C   . THR B 2 106 ? -31.285 -25.119 8.421   1.000 76.550  0 106 THR LLL C   1 ? 
ATOM   2346 O O   . THR B 2 106 ? -31.119 -23.985 7.932   1.000 62.563  0 106 THR LLL O   1 ? 
ATOM   2347 C CB  . THR B 2 106 ? -33.674 -25.463 7.814   1.000 79.535  0 106 THR LLL CB  1 ? 
ATOM   2348 O OG1 . THR B 2 106 ? -33.690 -24.133 7.308   1.000 98.150  0 106 THR LLL OG1 1 ? 
ATOM   2349 C CG2 . THR B 2 106 ? -35.061 -25.846 8.256   1.000 78.123  0 106 THR LLL CG2 1 ? 
ATOM   2350 N N   . LYS B 2 107 ? -30.333 -26.047 8.494   1.000 81.246  0 107 LYS LLL N   1 ? 
ATOM   2351 C CA  . LYS B 2 107 ? -28.941 -25.781 8.064   1.000 77.245  0 107 LYS LLL CA  1 ? 
ATOM   2352 C C   . LYS B 2 107 ? -28.912 -25.939 6.550   1.000 72.597  0 107 LYS LLL C   1 ? 
ATOM   2353 O O   . LYS B 2 107 ? -29.228 -27.038 6.073   1.000 71.281  0 107 LYS LLL O   1 ? 
ATOM   2354 C CB  . LYS B 2 107 ? -27.951 -26.704 8.780   1.000 84.567  0 107 LYS LLL CB  1 ? 
ATOM   2355 C CG  . LYS B 2 107 ? -26.492 -26.547 8.366   1.000 95.198  0 107 LYS LLL CG  1 ? 
ATOM   2356 C CD  . LYS B 2 107 ? -25.927 -25.152 8.577   1.000 99.208  0 107 LYS LLL CD  1 ? 
ATOM   2357 C CE  . LYS B 2 107 ? -24.834 -24.782 7.596   1.000 106.133 0 107 LYS LLL CE  1 ? 
ATOM   2358 N NZ  . LYS B 2 107 ? -25.073 -23.446 6.993   1.000 111.924 0 107 LYS LLL NZ  1 ? 
ATOM   2359 N N   . LEU B 2 108 ? -28.575 -24.867 5.833   1.000 69.199  0 108 LEU LLL N   1 ? 
ATOM   2360 C CA  . LEU B 2 108 ? -28.485 -24.880 4.354   1.000 65.500  0 108 LEU LLL CA  1 ? 
ATOM   2361 C C   . LEU B 2 108 ? -27.005 -24.855 3.962   1.000 67.292  0 108 LEU LLL C   1 ? 
ATOM   2362 O O   . LEU B 2 108 ? -26.329 -23.833 4.200   1.000 56.348  0 108 LEU LLL O   1 ? 
ATOM   2363 C CB  . LEU B 2 108 ? -29.269 -23.704 3.775   1.000 67.637  0 108 LEU LLL CB  1 ? 
ATOM   2364 C CG  . LEU B 2 108 ? -29.371 -23.677 2.247   1.000 69.601  0 108 LEU LLL CG  1 ? 
ATOM   2365 C CD1 . LEU B 2 108 ? -30.704 -23.116 1.792   1.000 67.256  0 108 LEU LLL CD1 1 ? 
ATOM   2366 C CD2 . LEU B 2 108 ? -28.234 -22.892 1.613   1.000 69.546  0 108 LEU LLL CD2 1 ? 
ATOM   2367 N N   . GLU B 2 109 ? -26.535 -25.979 3.415   1.000 79.747  0 109 GLU LLL N   1 ? 
ATOM   2368 C CA  . GLU B 2 109 ? -25.141 -26.187 2.970   1.000 85.556  0 109 GLU LLL CA  1 ? 
ATOM   2369 C C   . GLU B 2 109 ? -25.127 -26.014 1.453   1.000 83.636  0 109 GLU LLL C   1 ? 
ATOM   2370 O O   . GLU B 2 109 ? -25.876 -26.717 0.777   1.000 75.376  0 109 GLU LLL O   1 ? 
ATOM   2371 C CB  . GLU B 2 109 ? -24.623 -27.558 3.411   1.000 99.949  0 109 GLU LLL CB  1 ? 
ATOM   2372 C CG  . GLU B 2 109 ? -24.828 -27.836 4.893   1.000 114.949 0 109 GLU LLL CG  1 ? 
ATOM   2373 C CD  . GLU B 2 109 ? -25.752 -29.008 5.198   1.000 132.278 0 109 GLU LLL CD  1 ? 
ATOM   2374 O OE1 . GLU B 2 109 ? -26.986 -28.796 5.328   1.000 143.069 0 109 GLU LLL OE1 1 ? 
ATOM   2375 O OE2 . GLU B 2 109 ? -25.235 -30.136 5.321   1.000 144.964 0 109 GLU LLL OE2 1 ? 
ATOM   2376 N N   . ILE B 2 110 ? -24.345 -25.056 0.960   1.000 84.118  0 110 ILE LLL N   1 ? 
ATOM   2377 C CA  . ILE B 2 110 ? -24.071 -24.873 -0.492  1.000 77.763  0 110 ILE LLL CA  1 ? 
ATOM   2378 C C   . ILE B 2 110 ? -23.105 -25.980 -0.933  1.000 78.652  0 110 ILE LLL C   1 ? 
ATOM   2379 O O   . ILE B 2 110 ? -21.978 -26.014 -0.423  1.000 78.740  0 110 ILE LLL O   1 ? 
ATOM   2380 C CB  . ILE B 2 110 ? -23.523 -23.460 -0.760  1.000 77.765  0 110 ILE LLL CB  1 ? 
ATOM   2381 C CG1 . ILE B 2 110 ? -24.552 -22.380 -0.410  1.000 76.675  0 110 ILE LLL CG1 1 ? 
ATOM   2382 C CG2 . ILE B 2 110 ? -23.028 -23.336 -2.192  1.000 80.503  0 110 ILE LLL CG2 1 ? 
ATOM   2383 C CD1 . ILE B 2 110 ? -25.900 -22.559 -1.063  1.000 76.503  0 110 ILE LLL CD1 1 ? 
ATOM   2384 N N   . LYS B 2 111 ? -23.548 -26.859 -1.836  1.000 84.530  0 111 LYS LLL N   1 ? 
ATOM   2385 C CA  . LYS B 2 111 ? -22.750 -27.986 -2.396  1.000 82.784  0 111 LYS LLL CA  1 ? 
ATOM   2386 C C   . LYS B 2 111 ? -21.604 -27.437 -3.250  1.000 85.378  0 111 LYS LLL C   1 ? 
ATOM   2387 O O   . LYS B 2 111 ? -21.818 -26.445 -3.983  1.000 82.781  0 111 LYS LLL O   1 ? 
ATOM   2388 C CB  . LYS B 2 111 ? -23.636 -28.932 -3.217  1.000 78.656  0 111 LYS LLL CB  1 ? 
ATOM   2389 C CG  . LYS B 2 111 ? -24.384 -29.967 -2.384  1.000 79.408  0 111 LYS LLL CG  1 ? 
ATOM   2390 C CD  . LYS B 2 111 ? -24.983 -31.101 -3.183  1.000 76.793  0 111 LYS LLL CD  1 ? 
ATOM   2391 C CE  . LYS B 2 111 ? -26.259 -30.709 -3.892  1.000 82.524  0 111 LYS LLL CE  1 ? 
ATOM   2392 N NZ  . LYS B 2 111 ? -26.615 -31.683 -4.955  1.000 87.803  0 111 LYS LLL NZ  1 ? 
ATOM   2393 N N   . ARG B 2 112 ? -20.424 -28.053 -3.146  1.000 88.624  0 112 ARG LLL N   1 ? 
ATOM   2394 C CA  . ARG B 2 112 ? -19.256 -27.701 -3.990  1.000 92.317  0 112 ARG LLL CA  1 ? 
ATOM   2395 C C   . ARG B 2 112 ? -19.717 -27.807 -5.449  1.000 92.291  0 112 ARG LLL C   1 ? 
ATOM   2396 O O   . ARG B 2 112 ? -20.308 -28.852 -5.794  1.000 87.398  0 112 ARG LLL O   1 ? 
ATOM   2397 C CB  . ARG B 2 112 ? -18.073 -28.617 -3.648  1.000 91.211  0 112 ARG LLL CB  1 ? 
ATOM   2398 N N   . THR B 2 113 ? -19.520 -26.757 -6.256  1.000 95.279  0 113 THR LLL N   1 ? 
ATOM   2399 C CA  . THR B 2 113 ? -19.853 -26.755 -7.708  1.000 93.657  0 113 THR LLL CA  1 ? 
ATOM   2400 C C   . THR B 2 113 ? -18.984 -27.803 -8.414  1.000 84.366  0 113 THR LLL C   1 ? 
ATOM   2401 O O   . THR B 2 113 ? -17.739 -27.804 -8.227  1.000 75.173  0 113 THR LLL O   1 ? 
ATOM   2402 C CB  . THR B 2 113 ? -19.685 -25.375 -8.359  1.000 97.320  0 113 THR LLL CB  1 ? 
ATOM   2403 O OG1 . THR B 2 113 ? -18.355 -24.917 -8.082  1.000 103.923 0 113 THR LLL OG1 1 ? 
ATOM   2404 C CG2 . THR B 2 113 ? -20.734 -24.385 -7.892  1.000 94.534  0 113 THR LLL CG2 1 ? 
ATOM   2405 N N   . VAL B 2 114 ? -19.632 -28.695 -9.155  1.000 71.222  0 114 VAL LLL N   1 ? 
ATOM   2406 C CA  . VAL B 2 114 ? -18.957 -29.770 -9.927  1.000 63.318  0 114 VAL LLL CA  1 ? 
ATOM   2407 C C   . VAL B 2 114 ? -19.384 -29.592 -11.378 1.000 64.064  0 114 VAL LLL C   1 ? 
ATOM   2408 O O   . VAL B 2 114 ? -20.604 -29.582 -11.624 1.000 71.720  0 114 VAL LLL O   1 ? 
ATOM   2409 C CB  . VAL B 2 114 ? -19.297 -31.166 -9.369  1.000 62.260  0 114 VAL LLL CB  1 ? 
ATOM   2410 C CG1 . VAL B 2 114 ? -18.703 -32.291 -10.217 1.000 64.016  0 114 VAL LLL CG1 1 ? 
ATOM   2411 C CG2 . VAL B 2 114 ? -18.851 -31.304 -7.919  1.000 60.972  0 114 VAL LLL CG2 1 ? 
ATOM   2412 N N   . ALA B 2 115 ? -18.419 -29.404 -12.283 1.000 68.352  0 115 ALA LLL N   1 ? 
ATOM   2413 C CA  . ALA B 2 115 ? -18.653 -29.260 -13.740 1.000 72.129  0 115 ALA LLL CA  1 ? 
ATOM   2414 C C   . ALA B 2 115 ? -17.978 -30.427 -14.461 1.000 74.434  0 115 ALA LLL C   1 ? 
ATOM   2415 O O   . ALA B 2 115 ? -16.743 -30.537 -14.413 1.000 77.110  0 115 ALA LLL O   1 ? 
ATOM   2416 C CB  . ALA B 2 115 ? -18.143 -27.929 -14.232 1.000 71.766  0 115 ALA LLL CB  1 ? 
ATOM   2417 N N   . ALA B 2 116 ? -18.773 -31.294 -15.075 1.000 75.281  0 116 ALA LLL N   1 ? 
ATOM   2418 C CA  . ALA B 2 116 ? -18.267 -32.406 -15.897 1.000 78.134  0 116 ALA LLL CA  1 ? 
ATOM   2419 C C   . ALA B 2 116 ? -17.623 -31.791 -17.132 1.000 77.103  0 116 ALA LLL C   1 ? 
ATOM   2420 O O   . ALA B 2 116 ? -18.047 -30.738 -17.614 1.000 72.136  0 116 ALA LLL O   1 ? 
ATOM   2421 C CB  . ALA B 2 116 ? -19.386 -33.350 -16.244 1.000 80.576  0 116 ALA LLL CB  1 ? 
ATOM   2422 N N   . PRO B 2 117 ? -16.558 -32.418 -17.663 1.000 77.618  0 117 PRO LLL N   1 ? 
ATOM   2423 C CA  . PRO B 2 117 ? -15.957 -31.946 -18.903 1.000 78.348  0 117 PRO LLL CA  1 ? 
ATOM   2424 C C   . PRO B 2 117 ? -16.812 -32.353 -20.106 1.000 72.383  0 117 PRO LLL C   1 ? 
ATOM   2425 O O   . PRO B 2 117 ? -17.181 -33.494 -20.199 1.000 64.463  0 117 PRO LLL O   1 ? 
ATOM   2426 C CB  . PRO B 2 117 ? -14.595 -32.645 -18.945 1.000 80.732  0 117 PRO LLL CB  1 ? 
ATOM   2427 C CG  . PRO B 2 117 ? -14.800 -33.905 -18.120 1.000 82.498  0 117 PRO LLL CG  1 ? 
ATOM   2428 C CD  . PRO B 2 117 ? -15.870 -33.584 -17.095 1.000 79.308  0 117 PRO LLL CD  1 ? 
ATOM   2429 N N   . SER B 2 118 ? -17.099 -31.399 -20.984 1.000 76.916  0 118 SER LLL N   1 ? 
ATOM   2430 C CA  . SER B 2 118 ? -17.549 -31.686 -22.364 1.000 77.813  0 118 SER LLL CA  1 ? 
ATOM   2431 C C   . SER B 2 118 ? -16.346 -32.266 -23.110 1.000 71.948  0 118 SER LLL C   1 ? 
ATOM   2432 O O   . SER B 2 118 ? -15.372 -31.544 -23.327 1.000 71.719  0 118 SER LLL O   1 ? 
ATOM   2433 C CB  . SER B 2 118 ? -18.119 -30.459 -23.026 1.000 78.604  0 118 SER LLL CB  1 ? 
ATOM   2434 O OG  . SER B 2 118 ? -18.963 -29.761 -22.128 1.000 80.308  0 118 SER LLL OG  1 ? 
ATOM   2435 N N   . VAL B 2 119 ? -16.391 -33.548 -23.446 1.000 68.589  0 119 VAL LLL N   1 ? 
ATOM   2436 C CA  . VAL B 2 119 ? -15.262 -34.234 -24.126 1.000 69.321  0 119 VAL LLL CA  1 ? 
ATOM   2437 C C   . VAL B 2 119 ? -15.513 -34.286 -25.638 1.000 72.050  0 119 VAL LLL C   1 ? 
ATOM   2438 O O   . VAL B 2 119 ? -16.595 -34.707 -26.074 1.000 74.276  0 119 VAL LLL O   1 ? 
ATOM   2439 C CB  . VAL B 2 119 ? -15.053 -35.625 -23.522 1.000 75.472  0 119 VAL LLL CB  1 ? 
ATOM   2440 C CG1 . VAL B 2 119 ? -13.880 -36.350 -24.172 1.000 79.808  0 119 VAL LLL CG1 1 ? 
ATOM   2441 C CG2 . VAL B 2 119 ? -14.873 -35.514 -22.016 1.000 78.235  0 119 VAL LLL CG2 1 ? 
ATOM   2442 N N   . PHE B 2 120 ? -14.518 -33.870 -26.413 1.000 74.110  0 120 PHE LLL N   1 ? 
ATOM   2443 C CA  . PHE B 2 120 ? -14.567 -33.830 -27.896 1.000 78.881  0 120 PHE LLL CA  1 ? 
ATOM   2444 C C   . PHE B 2 120 ? -13.270 -34.419 -28.458 1.000 76.080  0 120 PHE LLL C   1 ? 
ATOM   2445 O O   . PHE B 2 120 ? -12.198 -33.990 -28.014 1.000 74.687  0 120 PHE LLL O   1 ? 
ATOM   2446 C CB  . PHE B 2 120 ? -14.764 -32.391 -28.376 1.000 73.957  0 120 PHE LLL CB  1 ? 
ATOM   2447 C CG  . PHE B 2 120 ? -15.974 -31.699 -27.811 1.000 69.358  0 120 PHE LLL CG  1 ? 
ATOM   2448 C CD1 . PHE B 2 120 ? -17.224 -31.937 -28.348 1.000 71.165  0 120 PHE LLL CD1 1 ? 
ATOM   2449 C CD2 . PHE B 2 120 ? -15.860 -30.802 -26.760 1.000 72.968  0 120 PHE LLL CD2 1 ? 
ATOM   2450 C CE1 . PHE B 2 120 ? -18.339 -31.288 -27.848 1.000 77.772  0 120 PHE LLL CE1 1 ? 
ATOM   2451 C CE2 . PHE B 2 120 ? -16.978 -30.161 -26.252 1.000 75.701  0 120 PHE LLL CE2 1 ? 
ATOM   2452 C CZ  . PHE B 2 120 ? -18.214 -30.400 -26.802 1.000 79.694  0 120 PHE LLL CZ  1 ? 
ATOM   2453 N N   . ILE B 2 121 ? -13.358 -35.370 -29.394 1.000 79.533  0 121 ILE LLL N   1 ? 
ATOM   2454 C CA  . ILE B 2 121 ? -12.157 -35.915 -30.101 1.000 78.948  0 121 ILE LLL CA  1 ? 
ATOM   2455 C C   . ILE B 2 121 ? -12.099 -35.275 -31.485 1.000 75.038  0 121 ILE LLL C   1 ? 
ATOM   2456 O O   . ILE B 2 121 ? -13.171 -34.918 -32.010 1.000 72.285  0 121 ILE LLL O   1 ? 
ATOM   2457 C CB  . ILE B 2 121 ? -12.146 -37.455 -30.174 1.000 78.044  0 121 ILE LLL CB  1 ? 
ATOM   2458 C CG1 . ILE B 2 121 ? -10.735 -37.974 -30.458 1.000 79.832  0 121 ILE LLL CG1 1 ? 
ATOM   2459 C CG2 . ILE B 2 121 ? -13.155 -37.981 -31.188 1.000 77.478  0 121 ILE LLL CG2 1 ? 
ATOM   2460 C CD1 . ILE B 2 121 ? -10.459 -39.360 -29.917 1.000 85.590  0 121 ILE LLL CD1 1 ? 
ATOM   2461 N N   . PHE B 2 122 ? -10.892 -35.113 -32.031 1.000 71.639  0 122 PHE LLL N   1 ? 
ATOM   2462 C CA  . PHE B 2 122 ? -10.665 -34.499 -33.363 1.000 73.364  0 122 PHE LLL CA  1 ? 
ATOM   2463 C C   . PHE B 2 122 ? -9.606  -35.279 -34.133 1.000 71.738  0 122 PHE LLL C   1 ? 
ATOM   2464 O O   . PHE B 2 122 ? -8.473  -35.424 -33.668 1.000 68.339  0 122 PHE LLL O   1 ? 
ATOM   2465 C CB  . PHE B 2 122 ? -10.245 -33.039 -33.220 1.000 67.838  0 122 PHE LLL CB  1 ? 
ATOM   2466 C CG  . PHE B 2 122 ? -11.275 -32.141 -32.600 1.000 62.315  0 122 PHE LLL CG  1 ? 
ATOM   2467 C CD1 . PHE B 2 122 ? -12.348 -31.682 -33.342 1.000 65.471  0 122 PHE LLL CD1 1 ? 
ATOM   2468 C CD2 . PHE B 2 122 ? -11.148 -31.732 -31.283 1.000 66.720  0 122 PHE LLL CD2 1 ? 
ATOM   2469 C CE1 . PHE B 2 122 ? -13.278 -30.822 -32.776 1.000 77.736  0 122 PHE LLL CE1 1 ? 
ATOM   2470 C CE2 . PHE B 2 122 ? -12.074 -30.869 -30.717 1.000 71.895  0 122 PHE LLL CE2 1 ? 
ATOM   2471 C CZ  . PHE B 2 122 ? -13.134 -30.410 -31.467 1.000 80.311  0 122 PHE LLL CZ  1 ? 
ATOM   2472 N N   . PRO B 2 123 ? -9.941  -35.786 -35.340 1.000 76.404  0 123 PRO LLL N   1 ? 
ATOM   2473 C CA  . PRO B 2 123 ? -8.961  -36.481 -36.170 1.000 81.959  0 123 PRO LLL CA  1 ? 
ATOM   2474 C C   . PRO B 2 123 ? -8.039  -35.492 -36.875 1.000 87.731  0 123 PRO LLL C   1 ? 
ATOM   2475 O O   . PRO B 2 123 ? -8.395  -34.324 -37.057 1.000 78.773  0 123 PRO LLL O   1 ? 
ATOM   2476 C CB  . PRO B 2 123 ? -9.834  -37.249 -37.165 1.000 78.490  0 123 PRO LLL CB  1 ? 
ATOM   2477 C CG  . PRO B 2 123 ? -11.052 -36.359 -37.324 1.000 79.121  0 123 PRO LLL CG  1 ? 
ATOM   2478 C CD  . PRO B 2 123 ? -11.273 -35.732 -35.964 1.000 76.914  0 123 PRO LLL CD  1 ? 
ATOM   2479 N N   . PRO B 2 124 ? -6.827  -35.935 -37.285 1.000 98.243  0 124 PRO LLL N   1 ? 
ATOM   2480 C CA  . PRO B 2 124 ? -5.933  -35.107 -38.090 1.000 99.474  0 124 PRO LLL CA  1 ? 
ATOM   2481 C C   . PRO B 2 124 ? -6.581  -34.680 -39.410 1.000 97.287  0 124 PRO LLL C   1 ? 
ATOM   2482 O O   . PRO B 2 124 ? -7.297  -35.481 -39.992 1.000 92.868  0 124 PRO LLL O   1 ? 
ATOM   2483 C CB  . PRO B 2 124 ? -4.740  -36.027 -38.381 1.000 101.259 0 124 PRO LLL CB  1 ? 
ATOM   2484 C CG  . PRO B 2 124 ? -4.757  -37.012 -37.238 1.000 97.576  0 124 PRO LLL CG  1 ? 
ATOM   2485 C CD  . PRO B 2 124 ? -6.230  -37.245 -36.975 1.000 96.471  0 124 PRO LLL CD  1 ? 
ATOM   2486 N N   . SER B 2 125 ? -6.295  -33.451 -39.841 1.000 93.838  0 125 SER LLL N   1 ? 
ATOM   2487 C CA  . SER B 2 125 ? -6.806  -32.870 -41.107 1.000 95.174  0 125 SER LLL CA  1 ? 
ATOM   2488 C C   . SER B 2 125 ? -6.058  -33.511 -42.277 1.000 92.772  0 125 SER LLL C   1 ? 
ATOM   2489 O O   . SER B 2 125 ? -4.866  -33.838 -42.102 1.000 91.766  0 125 SER LLL O   1 ? 
ATOM   2490 C CB  . SER B 2 125 ? -6.668  -31.373 -41.108 1.000 94.952  0 125 SER LLL CB  1 ? 
ATOM   2491 O OG  . SER B 2 125 ? -5.308  -30.988 -41.250 1.000 100.196 0 125 SER LLL OG  1 ? 
ATOM   2492 N N   . ASP B 2 126 ? -6.734  -33.690 -43.414 1.000 92.955  0 126 ASP LLL N   1 ? 
ATOM   2493 C CA  . ASP B 2 126 ? -6.113  -34.180 -44.674 1.000 100.883 0 126 ASP LLL CA  1 ? 
ATOM   2494 C C   . ASP B 2 126 ? -4.838  -33.359 -44.933 1.000 100.362 0 126 ASP LLL C   1 ? 
ATOM   2495 O O   . ASP B 2 126 ? -3.767  -33.973 -45.156 1.000 98.057  0 126 ASP LLL O   1 ? 
ATOM   2496 C CB  . ASP B 2 126 ? -7.122  -34.139 -45.829 1.000 102.422 0 126 ASP LLL CB  1 ? 
ATOM   2497 N N   . GLU B 2 127 ? -4.935  -32.027 -44.816 1.000 99.838  0 127 GLU LLL N   1 ? 
ATOM   2498 C CA  . GLU B 2 127 ? -3.839  -31.059 -45.111 1.000 105.171 0 127 GLU LLL CA  1 ? 
ATOM   2499 C C   . GLU B 2 127 ? -2.579  -31.409 -44.310 1.000 100.410 0 127 GLU LLL C   1 ? 
ATOM   2500 O O   . GLU B 2 127 ? -1.497  -30.943 -44.716 1.000 98.754  0 127 GLU LLL O   1 ? 
ATOM   2501 C CB  . GLU B 2 127 ? -4.239  -29.616 -44.780 1.000 110.110 0 127 GLU LLL CB  1 ? 
ATOM   2502 C CG  . GLU B 2 127 ? -5.507  -29.150 -45.472 1.000 123.621 0 127 GLU LLL CG  1 ? 
ATOM   2503 C CD  . GLU B 2 127 ? -6.778  -29.232 -44.637 1.000 129.610 0 127 GLU LLL CD  1 ? 
ATOM   2504 O OE1 . GLU B 2 127 ? -7.342  -30.351 -44.487 1.000 121.456 0 127 GLU LLL OE1 1 ? 
ATOM   2505 O OE2 . GLU B 2 127 ? -7.216  -28.164 -44.155 1.000 129.573 0 127 GLU LLL OE2 1 ? 
ATOM   2506 N N   . GLN B 2 128 ? -2.719  -32.161 -43.209 1.000 97.223  0 128 GLN LLL N   1 ? 
ATOM   2507 C CA  . GLN B 2 128 ? -1.617  -32.490 -42.265 1.000 93.287  0 128 GLN LLL CA  1 ? 
ATOM   2508 C C   . GLN B 2 128 ? -1.017  -33.846 -42.633 1.000 98.210  0 128 GLN LLL C   1 ? 
ATOM   2509 O O   . GLN B 2 128 ? 0.228   -33.969 -42.612 1.000 90.952  0 128 GLN LLL O   1 ? 
ATOM   2510 C CB  . GLN B 2 128 ? -2.127  -32.542 -40.828 1.000 89.078  0 128 GLN LLL CB  1 ? 
ATOM   2511 C CG  . GLN B 2 128 ? -1.080  -32.137 -39.812 1.000 80.530  0 128 GLN LLL CG  1 ? 
ATOM   2512 C CD  . GLN B 2 128 ? -1.289  -32.784 -38.469 1.000 81.810  0 128 GLN LLL CD  1 ? 
ATOM   2513 O OE1 . GLN B 2 128 ? -2.383  -33.212 -38.107 1.000 81.933  0 128 GLN LLL OE1 1 ? 
ATOM   2514 N NE2 . GLN B 2 128 ? -0.215  -32.851 -37.709 1.000 85.283  0 128 GLN LLL NE2 1 ? 
ATOM   2515 N N   . LEU B 2 129 ? -1.878  -34.818 -42.938 1.000 106.645 0 129 LEU LLL N   1 ? 
ATOM   2516 C CA  . LEU B 2 129 ? -1.464  -36.169 -43.395 1.000 119.525 0 129 LEU LLL CA  1 ? 
ATOM   2517 C C   . LEU B 2 129 ? -0.558  -35.996 -44.617 1.000 118.454 0 129 LEU LLL C   1 ? 
ATOM   2518 O O   . LEU B 2 129 ? 0.571   -36.532 -44.591 1.000 120.194 0 129 LEU LLL O   1 ? 
ATOM   2519 C CB  . LEU B 2 129 ? -2.711  -37.002 -43.711 1.000 122.734 0 129 LEU LLL CB  1 ? 
ATOM   2520 C CG  . LEU B 2 129 ? -3.667  -37.205 -42.537 1.000 127.237 0 129 LEU LLL CG  1 ? 
ATOM   2521 C CD1 . LEU B 2 129 ? -5.013  -37.742 -43.006 1.000 126.485 0 129 LEU LLL CD1 1 ? 
ATOM   2522 C CD2 . LEU B 2 129 ? -3.046  -38.121 -41.491 1.000 128.101 0 129 LEU LLL CD2 1 ? 
ATOM   2523 N N   . LYS B 2 130 ? -1.010  -35.210 -45.602 1.000 110.258 0 130 LYS LLL N   1 ? 
ATOM   2524 C CA  . LYS B 2 130 ? -0.218  -34.830 -46.804 1.000 113.266 0 130 LYS LLL CA  1 ? 
ATOM   2525 C C   . LYS B 2 130 ? 1.169   -34.336 -46.356 1.000 114.680 0 130 LYS LLL C   1 ? 
ATOM   2526 O O   . LYS B 2 130 ? 2.156   -34.680 -47.028 1.000 120.042 0 130 LYS LLL O   1 ? 
ATOM   2527 C CB  . LYS B 2 130 ? -0.966  -33.785 -47.645 1.000 103.883 0 130 LYS LLL CB  1 ? 
ATOM   2528 N N   . SER B 2 131 ? 1.252   -33.589 -45.248 1.000 114.797 0 131 SER LLL N   1 ? 
ATOM   2529 C CA  . SER B 2 131 ? 2.503   -32.956 -44.749 1.000 109.589 0 131 SER LLL CA  1 ? 
ATOM   2530 C C   . SER B 2 131 ? 3.345   -33.946 -43.931 1.000 110.034 0 131 SER LLL C   1 ? 
ATOM   2531 O O   . SER B 2 131 ? 4.463   -33.551 -43.568 1.000 110.707 0 131 SER LLL O   1 ? 
ATOM   2532 C CB  . SER B 2 131 ? 2.213   -31.703 -43.961 1.000 106.488 0 131 SER LLL CB  1 ? 
ATOM   2533 O OG  . SER B 2 131 ? 1.452   -30.791 -44.741 1.000 96.478  0 131 SER LLL OG  1 ? 
ATOM   2534 N N   . GLY B 2 132 ? 2.817   -35.140 -43.608 1.000 115.170 0 132 GLY LLL N   1 ? 
ATOM   2535 C CA  . GLY B 2 132 ? 3.592   -36.319 -43.153 1.000 113.273 0 132 GLY LLL CA  1 ? 
ATOM   2536 C C   . GLY B 2 132 ? 3.406   -36.677 -41.681 1.000 122.348 0 132 GLY LLL C   1 ? 
ATOM   2537 O O   . GLY B 2 132 ? 3.851   -37.770 -41.280 1.000 109.320 0 132 GLY LLL O   1 ? 
ATOM   2538 N N   . THR B 2 133 ? 2.791   -35.802 -40.879 1.000 134.226 0 133 THR LLL N   1 ? 
ATOM   2539 C CA  . THR B 2 133 ? 2.645   -35.988 -39.409 1.000 120.043 0 133 THR LLL CA  1 ? 
ATOM   2540 C C   . THR B 2 133 ? 1.151   -35.980 -39.042 1.000 107.304 0 133 THR LLL C   1 ? 
ATOM   2541 O O   . THR B 2 133 ? 0.384   -35.231 -39.674 1.000 89.632  0 133 THR LLL O   1 ? 
ATOM   2542 C CB  . THR B 2 133 ? 3.491   -34.956 -38.647 1.000 113.036 0 133 THR LLL CB  1 ? 
ATOM   2543 O OG1 . THR B 2 133 ? 4.795   -34.871 -39.230 1.000 97.336  0 133 THR LLL OG1 1 ? 
ATOM   2544 C CG2 . THR B 2 133 ? 3.612   -35.294 -37.177 1.000 107.894 0 133 THR LLL CG2 1 ? 
ATOM   2545 N N   . ALA B 2 134 ? 0.760   -36.821 -38.078 1.000 102.676 0 134 ALA LLL N   1 ? 
ATOM   2546 C CA  . ALA B 2 134 ? -0.630  -37.000 -37.591 1.000 98.270  0 134 ALA LLL CA  1 ? 
ATOM   2547 C C   . ALA B 2 134 ? -0.728  -36.430 -36.177 1.000 96.871  0 134 ALA LLL C   1 ? 
ATOM   2548 O O   . ALA B 2 134 ? 0.178   -36.726 -35.358 1.000 92.251  0 134 ALA LLL O   1 ? 
ATOM   2549 C CB  . ALA B 2 134 ? -1.014  -38.461 -37.614 1.000 97.613  0 134 ALA LLL CB  1 ? 
ATOM   2550 N N   . SER B 2 135 ? -1.767  -35.632 -35.907 1.000 97.149  0 135 SER LLL N   1 ? 
ATOM   2551 C CA  . SER B 2 135 ? -2.010  -35.021 -34.575 1.000 94.401  0 135 SER LLL CA  1 ? 
ATOM   2552 C C   . SER B 2 135 ? -3.492  -35.108 -34.197 1.000 93.997  0 135 SER LLL C   1 ? 
ATOM   2553 O O   . SER B 2 135 ? -4.307  -34.302 -34.699 1.000 89.124  0 135 SER LLL O   1 ? 
ATOM   2554 C CB  . SER B 2 135 ? -1.471  -33.620 -34.513 1.000 89.318  0 135 SER LLL CB  1 ? 
ATOM   2555 O OG  . SER B 2 135 ? -0.128  -33.636 -34.043 1.000 83.726  0 135 SER LLL OG  1 ? 
ATOM   2556 N N   . VAL B 2 136 ? -3.807  -36.051 -33.310 1.000 94.530  0 136 VAL LLL N   1 ? 
ATOM   2557 C CA  . VAL B 2 136 ? -5.166  -36.256 -32.733 1.000 95.246  0 136 VAL LLL CA  1 ? 
ATOM   2558 C C   . VAL B 2 136 ? -5.271  -35.379 -31.481 1.000 87.126  0 136 VAL LLL C   1 ? 
ATOM   2559 O O   . VAL B 2 136 ? -4.269  -35.282 -30.731 1.000 85.138  0 136 VAL LLL O   1 ? 
ATOM   2560 C CB  . VAL B 2 136 ? -5.427  -37.741 -32.415 1.000 95.912  0 136 VAL LLL CB  1 ? 
ATOM   2561 C CG1 . VAL B 2 136 ? -6.889  -37.987 -32.088 1.000 93.913  0 136 VAL LLL CG1 1 ? 
ATOM   2562 C CG2 . VAL B 2 136 ? -4.978  -38.655 -33.547 1.000 92.567  0 136 VAL LLL CG2 1 ? 
ATOM   2563 N N   . VAL B 2 137 ? -6.433  -34.754 -31.276 1.000 83.422  0 137 VAL LLL N   1 ? 
ATOM   2564 C CA  . VAL B 2 137 ? -6.672  -33.789 -30.162 1.000 75.652  0 137 VAL LLL CA  1 ? 
ATOM   2565 C C   . VAL B 2 137 ? -7.932  -34.200 -29.403 1.000 72.693  0 137 VAL LLL C   1 ? 
ATOM   2566 O O   . VAL B 2 137 ? -8.997  -34.392 -30.030 1.000 62.973  0 137 VAL LLL O   1 ? 
ATOM   2567 C CB  . VAL B 2 137 ? -6.774  -32.335 -30.660 1.000 76.783  0 137 VAL LLL CB  1 ? 
ATOM   2568 C CG1 . VAL B 2 137 ? -7.031  -31.359 -29.520 1.000 77.768  0 137 VAL LLL CG1 1 ? 
ATOM   2569 C CG2 . VAL B 2 137 ? -5.537  -31.921 -31.437 1.000 79.543  0 137 VAL LLL CG2 1 ? 
ATOM   2570 N N   . CYS B 2 138 ? -7.784  -34.319 -28.089 1.000 81.434  0 138 CYS LLL N   1 ? 
ATOM   2571 C CA  . CYS B 2 138 ? -8.866  -34.603 -27.125 1.000 86.255  0 138 CYS LLL CA  1 ? 
ATOM   2572 C C   . CYS B 2 138 ? -9.074  -33.362 -26.262 1.000 86.928  0 138 CYS LLL C   1 ? 
ATOM   2573 O O   . CYS B 2 138 ? -8.145  -32.973 -25.523 1.000 84.617  0 138 CYS LLL O   1 ? 
ATOM   2574 C CB  . CYS B 2 138 ? -8.530  -35.790 -26.238 1.000 91.647  0 138 CYS LLL CB  1 ? 
ATOM   2575 S SG  . CYS B 2 138 ? -10.002 -36.622 -25.600 1.000 107.066 0 138 CYS LLL SG  1 ? 
ATOM   2576 N N   . LEU B 2 139 ? -10.265 -32.780 -26.356 1.000 84.883  0 139 LEU LLL N   1 ? 
ATOM   2577 C CA  . LEU B 2 139 ? -10.669 -31.582 -25.586 1.000 76.843  0 139 LEU LLL CA  1 ? 
ATOM   2578 C C   . LEU B 2 139 ? -11.526 -32.002 -24.386 1.000 67.731  0 139 LEU LLL C   1 ? 
ATOM   2579 O O   . LEU B 2 139 ? -12.590 -32.577 -24.599 1.000 74.355  0 139 LEU LLL O   1 ? 
ATOM   2580 C CB  . LEU B 2 139 ? -11.433 -30.654 -26.532 1.000 71.504  0 139 LEU LLL CB  1 ? 
ATOM   2581 C CG  . LEU B 2 139 ? -11.869 -29.335 -25.914 1.000 76.461  0 139 LEU LLL CG  1 ? 
ATOM   2582 C CD1 . LEU B 2 139 ? -10.661 -28.483 -25.574 1.000 74.692  0 139 LEU LLL CD1 1 ? 
ATOM   2583 C CD2 . LEU B 2 139 ? -12.808 -28.588 -26.844 1.000 84.179  0 139 LEU LLL CD2 1 ? 
ATOM   2584 N N   . LEU B 2 140 ? -11.070 -31.714 -23.170 1.000 64.149  0 140 LEU LLL N   1 ? 
ATOM   2585 C CA  . LEU B 2 140 ? -11.913 -31.719 -21.951 1.000 67.763  0 140 LEU LLL CA  1 ? 
ATOM   2586 C C   . LEU B 2 140 ? -12.364 -30.286 -21.714 1.000 67.174  0 140 LEU LLL C   1 ? 
ATOM   2587 O O   . LEU B 2 140 ? -11.500 -29.481 -21.356 1.000 66.624  0 140 LEU LLL O   1 ? 
ATOM   2588 C CB  . LEU B 2 140 ? -11.093 -32.214 -20.763 1.000 73.619  0 140 LEU LLL CB  1 ? 
ATOM   2589 C CG  . LEU B 2 140 ? -10.936 -33.725 -20.677 1.000 84.727  0 140 LEU LLL CG  1 ? 
ATOM   2590 C CD1 . LEU B 2 140 ? -10.335 -34.291 -21.961 1.000 87.708  0 140 LEU LLL CD1 1 ? 
ATOM   2591 C CD2 . LEU B 2 140 ? -10.102 -34.097 -19.462 1.000 84.696  0 140 LEU LLL CD2 1 ? 
ATOM   2592 N N   . ASN B 2 141 ? -13.647 -29.980 -21.910 1.000 69.425  0 141 ASN LLL N   1 ? 
ATOM   2593 C CA  . ASN B 2 141 ? -14.112 -28.570 -21.895 1.000 69.940  0 141 ASN LLL CA  1 ? 
ATOM   2594 C C   . ASN B 2 141 ? -14.912 -28.265 -20.626 1.000 69.592  0 141 ASN LLL C   1 ? 
ATOM   2595 O O   . ASN B 2 141 ? -15.811 -29.040 -20.283 1.000 68.224  0 141 ASN LLL O   1 ? 
ATOM   2596 C CB  . ASN B 2 141 ? -14.879 -28.204 -23.164 1.000 72.271  0 141 ASN LLL CB  1 ? 
ATOM   2597 C CG  . ASN B 2 141 ? -14.477 -26.831 -23.667 1.000 79.156  0 141 ASN LLL CG  1 ? 
ATOM   2598 O OD1 . ASN B 2 141 ? -13.292 -26.522 -23.791 1.000 83.832  0 141 ASN LLL OD1 1 ? 
ATOM   2599 N ND2 . ASN B 2 141 ? -15.451 -25.975 -23.917 1.000 83.298  0 141 ASN LLL ND2 1 ? 
ATOM   2600 N N   . ASN B 2 142 ? -14.586 -27.142 -19.979 1.000 73.116  0 142 ASN LLL N   1 ? 
ATOM   2601 C CA  . ASN B 2 142 ? -15.317 -26.579 -18.812 1.000 71.317  0 142 ASN LLL CA  1 ? 
ATOM   2602 C C   . ASN B 2 142 ? -15.496 -27.633 -17.711 1.000 72.472  0 142 ASN LLL C   1 ? 
ATOM   2603 O O   . ASN B 2 142 ? -16.653 -28.020 -17.419 1.000 81.364  0 142 ASN LLL O   1 ? 
ATOM   2604 C CB  . ASN B 2 142 ? -16.655 -26.019 -19.273 1.000 73.789  0 142 ASN LLL CB  1 ? 
ATOM   2605 C CG  . ASN B 2 142 ? -16.515 -25.156 -20.510 1.000 78.886  0 142 ASN LLL CG  1 ? 
ATOM   2606 O OD1 . ASN B 2 142 ? -15.565 -24.388 -20.650 1.000 72.340  0 142 ASN LLL OD1 1 ? 
ATOM   2607 N ND2 . ASN B 2 142 ? -17.466 -25.268 -21.421 1.000 85.141  0 142 ASN LLL ND2 1 ? 
ATOM   2608 N N   . PHE B 2 143 ? -14.404 -28.086 -17.097 1.000 69.770  0 143 PHE LLL N   1 ? 
ATOM   2609 C CA  . PHE B 2 143 ? -14.477 -29.067 -15.984 1.000 70.130  0 143 PHE LLL CA  1 ? 
ATOM   2610 C C   . PHE B 2 143 ? -14.067 -28.414 -14.667 1.000 70.574  0 143 PHE LLL C   1 ? 
ATOM   2611 O O   . PHE B 2 143 ? -13.213 -27.532 -14.642 1.000 72.833  0 143 PHE LLL O   1 ? 
ATOM   2612 C CB  . PHE B 2 143 ? -13.675 -30.343 -16.263 1.000 70.514  0 143 PHE LLL CB  1 ? 
ATOM   2613 C CG  . PHE B 2 143 ? -12.203 -30.156 -16.486 1.000 70.823  0 143 PHE LLL CG  1 ? 
ATOM   2614 C CD1 . PHE B 2 143 ? -11.702 -29.940 -17.756 1.000 73.649  0 143 PHE LLL CD1 1 ? 
ATOM   2615 C CD2 . PHE B 2 143 ? -11.326 -30.201 -15.418 1.000 80.266  0 143 PHE LLL CD2 1 ? 
ATOM   2616 C CE1 . PHE B 2 143 ? -10.344 -29.765 -17.952 1.000 83.369  0 143 PHE LLL CE1 1 ? 
ATOM   2617 C CE2 . PHE B 2 143 ? -9.970  -30.010 -15.610 1.000 89.244  0 143 PHE LLL CE2 1 ? 
ATOM   2618 C CZ  . PHE B 2 143 ? -9.482  -29.796 -16.880 1.000 91.508  0 143 PHE LLL CZ  1 ? 
ATOM   2619 N N   . TYR B 2 144 ? -14.653 -28.892 -13.571 1.000 77.850  0 144 TYR LLL N   1 ? 
ATOM   2620 C CA  . TYR B 2 144 ? -14.367 -28.408 -12.200 1.000 77.048  0 144 TYR LLL CA  1 ? 
ATOM   2621 C C   . TYR B 2 144 ? -14.734 -29.494 -11.201 1.000 77.712  0 144 TYR LLL C   1 ? 
ATOM   2622 O O   . TYR B 2 144 ? -15.871 -29.952 -11.194 1.000 76.287  0 144 TYR LLL O   1 ? 
ATOM   2623 C CB  . TYR B 2 144 ? -15.143 -27.118 -11.932 1.000 89.742  0 144 TYR LLL CB  1 ? 
ATOM   2624 C CG  . TYR B 2 144 ? -14.609 -26.341 -10.762 1.000 97.176  0 144 TYR LLL CG  1 ? 
ATOM   2625 C CD1 . TYR B 2 144 ? -13.259 -26.062 -10.679 1.000 109.703 0 144 TYR LLL CD1 1 ? 
ATOM   2626 C CD2 . TYR B 2 144 ? -15.433 -25.889 -9.747  1.000 112.430 0 144 TYR LLL CD2 1 ? 
ATOM   2627 C CE1 . TYR B 2 144 ? -12.733 -25.351 -9.619  1.000 117.461 0 144 TYR LLL CE1 1 ? 
ATOM   2628 C CE2 . TYR B 2 144 ? -14.927 -25.160 -8.684  1.000 120.401 0 144 TYR LLL CE2 1 ? 
ATOM   2629 C CZ  . TYR B 2 144 ? -13.571 -24.893 -8.620  1.000 120.312 0 144 TYR LLL CZ  1 ? 
ATOM   2630 O OH  . TYR B 2 144 ? -13.052 -24.182 -7.579  1.000 121.758 0 144 TYR LLL OH  1 ? 
ATOM   2631 N N   . PRO B 2 145 ? -13.828 -29.940 -10.302 1.000 92.084  0 145 PRO LLL N   1 ? 
ATOM   2632 C CA  . PRO B 2 145 ? -12.520 -29.312 -10.068 1.000 98.209  0 145 PRO LLL CA  1 ? 
ATOM   2633 C C   . PRO B 2 145 ? -11.370 -29.776 -10.985 1.000 92.707  0 145 PRO LLL C   1 ? 
ATOM   2634 O O   . PRO B 2 145 ? -11.569 -30.651 -11.807 1.000 87.814  0 145 PRO LLL O   1 ? 
ATOM   2635 C CB  . PRO B 2 145 ? -12.264 -29.705 -8.609  1.000 102.473 0 145 PRO LLL CB  1 ? 
ATOM   2636 C CG  . PRO B 2 145 ? -12.852 -31.105 -8.512  1.000 97.676  0 145 PRO LLL CG  1 ? 
ATOM   2637 C CD  . PRO B 2 145 ? -14.058 -31.101 -9.429  1.000 89.820  0 145 PRO LLL CD  1 ? 
ATOM   2638 N N   . ARG B 2 146 ? -10.196 -29.161 -10.834 1.000 82.903  0 146 ARG LLL N   1 ? 
ATOM   2639 C CA  . ARG B 2 146 ? -9.040  -29.356 -11.742 1.000 81.925  0 146 ARG LLL CA  1 ? 
ATOM   2640 C C   . ARG B 2 146 ? -8.749  -30.857 -11.912 1.000 76.405  0 146 ARG LLL C   1 ? 
ATOM   2641 O O   . ARG B 2 146 ? -8.475  -31.265 -13.053 1.000 71.664  0 146 ARG LLL O   1 ? 
ATOM   2642 C CB  . ARG B 2 146 ? -7.840  -28.563 -11.211 1.000 88.144  0 146 ARG LLL CB  1 ? 
ATOM   2643 C CG  . ARG B 2 146 ? -6.524  -28.793 -11.948 1.000 90.090  0 146 ARG LLL CG  1 ? 
ATOM   2644 C CD  . ARG B 2 146 ? -6.514  -28.328 -13.395 1.000 82.021  0 146 ARG LLL CD  1 ? 
ATOM   2645 N NE  . ARG B 2 146 ? -5.344  -28.750 -14.158 1.000 71.256  0 146 ARG LLL NE  1 ? 
ATOM   2646 C CZ  . ARG B 2 146 ? -5.144  -29.979 -14.625 1.000 69.992  0 146 ARG LLL CZ  1 ? 
ATOM   2647 N NH1 . ARG B 2 146 ? -6.015  -30.955 -14.402 1.000 68.627  0 146 ARG LLL NH1 1 ? 
ATOM   2648 N NH2 . ARG B 2 146 ? -4.043  -30.238 -15.304 1.000 74.454  0 146 ARG LLL NH2 1 ? 
ATOM   2649 N N   . GLU B 2 147 ? -8.765  -31.653 -10.837 1.000 80.144  0 147 GLU LLL N   1 ? 
ATOM   2650 C CA  . GLU B 2 147 ? -8.339  -33.085 -10.900 1.000 86.299  0 147 GLU LLL CA  1 ? 
ATOM   2651 C C   . GLU B 2 147 ? -9.174  -33.787 -11.979 1.000 82.393  0 147 GLU LLL C   1 ? 
ATOM   2652 O O   . GLU B 2 147 ? -10.406 -33.668 -11.941 1.000 92.128  0 147 GLU LLL O   1 ? 
ATOM   2653 C CB  . GLU B 2 147 ? -8.448  -33.793 -9.541  1.000 78.036  0 147 GLU LLL CB  1 ? 
ATOM   2654 N N   . ALA B 2 148 ? -8.524  -34.448 -12.936 1.000 81.589  0 148 ALA LLL N   1 ? 
ATOM   2655 C CA  . ALA B 2 148 ? -9.192  -35.145 -14.057 1.000 84.122  0 148 ALA LLL CA  1 ? 
ATOM   2656 C C   . ALA B 2 148 ? -8.200  -36.078 -14.747 1.000 88.942  0 148 ALA LLL C   1 ? 
ATOM   2657 O O   . ALA B 2 148 ? -7.248  -35.564 -15.338 1.000 85.727  0 148 ALA LLL O   1 ? 
ATOM   2658 C CB  . ALA B 2 148 ? -9.736  -34.137 -15.032 1.000 84.679  0 148 ALA LLL CB  1 ? 
ATOM   2659 N N   . LYS B 2 149 ? -8.434  -37.391 -14.672 1.000 96.972  0 149 LYS LLL N   1 ? 
ATOM   2660 C CA  . LYS B 2 149 ? -7.573  -38.437 -15.285 1.000 93.853  0 149 LYS LLL CA  1 ? 
ATOM   2661 C C   . LYS B 2 149 ? -8.202  -38.874 -16.616 1.000 97.616  0 149 LYS LLL C   1 ? 
ATOM   2662 O O   . LYS B 2 149 ? -9.266  -39.520 -16.598 1.000 115.553 0 149 LYS LLL O   1 ? 
ATOM   2663 C CB  . LYS B 2 149 ? -7.381  -39.606 -14.314 1.000 92.056  0 149 LYS LLL CB  1 ? 
ATOM   2664 N N   . TYR B 2 150 ? -7.567  -38.503 -17.726 1.000 92.867  0 150 TYR LLL N   1 ? 
ATOM   2665 C CA  . TYR B 2 150 ? -7.910  -38.922 -19.109 1.000 96.252  0 150 TYR LLL CA  1 ? 
ATOM   2666 C C   . TYR B 2 150 ? -6.777  -39.817 -19.628 1.000 100.171 0 150 TYR LLL C   1 ? 
ATOM   2667 O O   . TYR B 2 150 ? -5.685  -39.799 -19.017 1.000 103.627 0 150 TYR LLL O   1 ? 
ATOM   2668 C CB  . TYR B 2 150 ? -8.093  -37.693 -20.005 1.000 96.914  0 150 TYR LLL CB  1 ? 
ATOM   2669 C CG  . TYR B 2 150 ? -6.788  -37.069 -20.423 1.000 84.914  0 150 TYR LLL CG  1 ? 
ATOM   2670 C CD1 . TYR B 2 150 ? -6.107  -36.231 -19.560 1.000 83.299  0 150 TYR LLL CD1 1 ? 
ATOM   2671 C CD2 . TYR B 2 150 ? -6.201  -37.375 -21.640 1.000 77.548  0 150 TYR LLL CD2 1 ? 
ATOM   2672 C CE1 . TYR B 2 150 ? -4.882  -35.687 -19.904 1.000 90.652  0 150 TYR LLL CE1 1 ? 
ATOM   2673 C CE2 . TYR B 2 150 ? -4.982  -36.834 -22.002 1.000 81.875  0 150 TYR LLL CE2 1 ? 
ATOM   2674 C CZ  . TYR B 2 150 ? -4.320  -35.985 -21.131 1.000 86.660  0 150 TYR LLL CZ  1 ? 
ATOM   2675 O OH  . TYR B 2 150 ? -3.115  -35.429 -21.445 1.000 85.261  0 150 TYR LLL OH  1 ? 
ATOM   2676 N N   . GLN B 2 151 ? -7.004  -40.550 -20.722 1.000 103.702 0 151 GLN LLL N   1 ? 
ATOM   2677 C CA  . GLN B 2 151 ? -5.976  -41.442 -21.326 1.000 111.437 0 151 GLN LLL CA  1 ? 
ATOM   2678 C C   . GLN B 2 151 ? -6.322  -41.744 -22.790 1.000 111.805 0 151 GLN LLL C   1 ? 
ATOM   2679 O O   . GLN B 2 151 ? -7.496  -42.083 -23.086 1.000 103.851 0 151 GLN LLL O   1 ? 
ATOM   2680 C CB  . GLN B 2 151 ? -5.800  -42.727 -20.507 1.000 114.687 0 151 GLN LLL CB  1 ? 
ATOM   2681 C CG  . GLN B 2 151 ? -7.049  -43.591 -20.410 1.000 123.462 0 151 GLN LLL CG  1 ? 
ATOM   2682 C CD  . GLN B 2 151 ? -6.790  -44.856 -19.630 1.000 128.160 0 151 GLN LLL CD  1 ? 
ATOM   2683 O OE1 . GLN B 2 151 ? -5.852  -44.941 -18.841 1.000 124.717 0 151 GLN LLL OE1 1 ? 
ATOM   2684 N NE2 . GLN B 2 151 ? -7.634  -45.852 -19.839 1.000 138.668 0 151 GLN LLL NE2 1 ? 
ATOM   2685 N N   . TRP B 2 152 ? -5.319  -41.598 -23.663 1.000 108.459 0 152 TRP LLL N   1 ? 
ATOM   2686 C CA  . TRP B 2 152 ? -5.344  -42.020 -25.087 1.000 99.425  0 152 TRP LLL CA  1 ? 
ATOM   2687 C C   . TRP B 2 152 ? -5.255  -43.550 -25.144 1.000 100.807 0 152 TRP LLL C   1 ? 
ATOM   2688 O O   . TRP B 2 152 ? -4.364  -44.117 -24.492 1.000 85.449  0 152 TRP LLL O   1 ? 
ATOM   2689 C CB  . TRP B 2 152 ? -4.196  -41.355 -25.853 1.000 92.856  0 152 TRP LLL CB  1 ? 
ATOM   2690 C CG  . TRP B 2 152 ? -4.327  -39.877 -26.059 1.000 83.369  0 152 TRP LLL CG  1 ? 
ATOM   2691 C CD1 . TRP B 2 152 ? -3.658  -38.876 -25.411 1.000 75.506  0 152 TRP LLL CD1 1 ? 
ATOM   2692 C CD2 . TRP B 2 152 ? -5.166  -39.231 -27.029 1.000 76.464  0 152 TRP LLL CD2 1 ? 
ATOM   2693 N NE1 . TRP B 2 152 ? -4.036  -37.655 -25.904 1.000 70.810  0 152 TRP LLL NE1 1 ? 
ATOM   2694 C CE2 . TRP B 2 152 ? -4.955  -37.840 -26.901 1.000 71.981  0 152 TRP LLL CE2 1 ? 
ATOM   2695 C CE3 . TRP B 2 152 ? -6.072  -39.694 -27.988 1.000 78.165  0 152 TRP LLL CE3 1 ? 
ATOM   2696 C CZ2 . TRP B 2 152 ? -5.607  -36.914 -27.714 1.000 73.204  0 152 TRP LLL CZ2 1 ? 
ATOM   2697 C CZ3 . TRP B 2 152 ? -6.727  -38.778 -28.780 1.000 79.986  0 152 TRP LLL CZ3 1 ? 
ATOM   2698 C CH2 . TRP B 2 152 ? -6.495  -37.408 -28.644 1.000 78.768  0 152 TRP LLL CH2 1 ? 
ATOM   2699 N N   . LYS B 2 153 ? -6.175  -44.192 -25.856 1.000 107.840 0 153 LYS LLL N   1 ? 
ATOM   2700 C CA  . LYS B 2 153 ? -6.216  -45.668 -26.011 1.000 117.136 0 153 LYS LLL CA  1 ? 
ATOM   2701 C C   . LYS B 2 153 ? -6.490  -45.962 -27.486 1.000 135.914 0 153 LYS LLL C   1 ? 
ATOM   2702 O O   . LYS B 2 153 ? -7.645  -45.782 -27.920 1.000 132.010 0 153 LYS LLL O   1 ? 
ATOM   2703 C CB  . LYS B 2 153 ? -7.271  -46.283 -25.081 1.000 110.956 0 153 LYS LLL CB  1 ? 
ATOM   2704 N N   . VAL B 2 154 ? -5.461  -46.369 -28.235 1.000 149.357 0 154 VAL LLL N   1 ? 
ATOM   2705 C CA  . VAL B 2 154 ? -5.566  -46.645 -29.699 1.000 144.790 0 154 VAL LLL CA  1 ? 
ATOM   2706 C C   . VAL B 2 154 ? -5.775  -48.147 -29.908 1.000 137.132 0 154 VAL LLL C   1 ? 
ATOM   2707 O O   . VAL B 2 154 ? -4.883  -48.932 -29.516 1.000 124.950 0 154 VAL LLL O   1 ? 
ATOM   2708 C CB  . VAL B 2 154 ? -4.329  -46.127 -30.449 1.000 145.696 0 154 VAL LLL CB  1 ? 
ATOM   2709 C CG1 . VAL B 2 154 ? -4.360  -46.520 -31.917 1.000 148.744 0 154 VAL LLL CG1 1 ? 
ATOM   2710 C CG2 . VAL B 2 154 ? -4.189  -44.620 -30.290 1.000 148.650 0 154 VAL LLL CG2 1 ? 
ATOM   2711 N N   . ASP B 2 155 ? -6.912  -48.524 -30.505 1.000 132.429 0 155 ASP LLL N   1 ? 
ATOM   2712 C CA  . ASP B 2 155 ? -7.339  -49.941 -30.659 1.000 128.232 0 155 ASP LLL CA  1 ? 
ATOM   2713 C C   . ASP B 2 155 ? -7.111  -50.664 -29.322 1.000 134.742 0 155 ASP LLL C   1 ? 
ATOM   2714 O O   . ASP B 2 155 ? -6.374  -51.672 -29.305 1.000 143.052 0 155 ASP LLL O   1 ? 
ATOM   2715 C CB  . ASP B 2 155 ? -6.593  -50.605 -31.818 1.000 121.652 0 155 ASP LLL CB  1 ? 
ATOM   2716 C CG  . ASP B 2 155 ? -6.865  -49.980 -33.178 1.000 124.937 0 155 ASP LLL CG  1 ? 
ATOM   2717 O OD1 . ASP B 2 155 ? -7.092  -48.751 -33.251 1.000 132.668 0 155 ASP LLL OD1 1 ? 
ATOM   2718 O OD2 . ASP B 2 155 ? -6.843  -50.726 -34.162 1.000 123.328 0 155 ASP LLL OD2 1 ? 
ATOM   2719 N N   . ASN B 2 156 ? -7.681  -50.121 -28.241 1.000 131.264 0 156 ASN LLL N   1 ? 
ATOM   2720 C CA  . ASN B 2 156 ? -7.586  -50.635 -26.845 1.000 122.066 0 156 ASN LLL CA  1 ? 
ATOM   2721 C C   . ASN B 2 156 ? -6.117  -50.876 -26.475 1.000 111.973 0 156 ASN LLL C   1 ? 
ATOM   2722 O O   . ASN B 2 156 ? -5.791  -51.978 -26.033 1.000 110.153 0 156 ASN LLL O   1 ? 
ATOM   2723 C CB  . ASN B 2 156 ? -8.444  -51.888 -26.647 1.000 118.052 0 156 ASN LLL CB  1 ? 
ATOM   2724 C CG  . ASN B 2 156 ? -9.926  -51.580 -26.621 1.000 115.421 0 156 ASN LLL CG  1 ? 
ATOM   2725 O OD1 . ASN B 2 156 ? -10.466 -51.007 -27.565 1.000 113.627 0 156 ASN LLL OD1 1 ? 
ATOM   2726 N ND2 . ASN B 2 156 ? -10.593 -51.955 -25.543 1.000 113.408 0 156 ASN LLL ND2 1 ? 
ATOM   2727 N N   . ALA B 2 157 ? -5.263  -49.870 -26.638 1.000 113.792 0 157 ALA LLL N   1 ? 
ATOM   2728 C CA  . ALA B 2 157 ? -3.845  -49.917 -26.220 1.000 123.766 0 157 ALA LLL CA  1 ? 
ATOM   2729 C C   . ALA B 2 157 ? -3.447  -48.563 -25.628 1.000 123.071 0 157 ALA LLL C   1 ? 
ATOM   2730 O O   . ALA B 2 157 ? -3.445  -47.561 -26.380 1.000 112.857 0 157 ALA LLL O   1 ? 
ATOM   2731 C CB  . ALA B 2 157 ? -2.980  -50.304 -27.393 1.000 129.593 0 157 ALA LLL CB  1 ? 
ATOM   2732 N N   . LEU B 2 158 ? -3.145  -48.545 -24.325 1.000 130.359 0 158 LEU LLL N   1 ? 
ATOM   2733 C CA  . LEU B 2 158 ? -2.716  -47.335 -23.573 1.000 135.710 0 158 LEU LLL CA  1 ? 
ATOM   2734 C C   . LEU B 2 158 ? -1.432  -46.783 -24.198 1.000 128.529 0 158 LEU LLL C   1 ? 
ATOM   2735 O O   . LEU B 2 158 ? -0.387  -47.452 -24.087 1.000 120.484 0 158 LEU LLL O   1 ? 
ATOM   2736 C CB  . LEU B 2 158 ? -2.496  -47.681 -22.096 1.000 145.712 0 158 LEU LLL CB  1 ? 
ATOM   2737 C CG  . LEU B 2 158 ? -3.726  -47.552 -21.198 1.000 157.019 0 158 LEU LLL CG  1 ? 
ATOM   2738 C CD1 . LEU B 2 158 ? -4.924  -48.286 -21.787 1.000 159.643 0 158 LEU LLL CD1 1 ? 
ATOM   2739 C CD2 . LEU B 2 158 ? -3.424  -48.057 -19.791 1.000 156.283 0 158 LEU LLL CD2 1 ? 
ATOM   2740 N N   . GLN B 2 159 ? -1.529  -45.598 -24.809 1.000 124.447 0 159 GLN LLL N   1 ? 
ATOM   2741 C CA  . GLN B 2 159 ? -0.390  -44.840 -25.388 1.000 112.070 0 159 GLN LLL CA  1 ? 
ATOM   2742 C C   . GLN B 2 159 ? 0.320   -44.126 -24.237 1.000 99.237  0 159 GLN LLL C   1 ? 
ATOM   2743 O O   . GLN B 2 159 ? -0.318  -43.899 -23.198 1.000 84.375  0 159 GLN LLL O   1 ? 
ATOM   2744 C CB  . GLN B 2 159 ? -0.872  -43.841 -26.444 1.000 114.187 0 159 GLN LLL CB  1 ? 
ATOM   2745 C CG  . GLN B 2 159 ? -1.891  -44.403 -27.430 1.000 126.113 0 159 GLN LLL CG  1 ? 
ATOM   2746 C CD  . GLN B 2 159 ? -1.292  -45.367 -28.420 1.000 128.719 0 159 GLN LLL CD  1 ? 
ATOM   2747 O OE1 . GLN B 2 159 ? -1.494  -46.574 -28.333 1.000 134.755 0 159 GLN LLL OE1 1 ? 
ATOM   2748 N NE2 . GLN B 2 159 ? -0.546  -44.833 -29.373 1.000 128.463 0 159 GLN LLL NE2 1 ? 
ATOM   2749 N N   . SER B 2 160 ? 1.600   -43.805 -24.407 1.000 100.477 0 160 SER LLL N   1 ? 
ATOM   2750 C CA  . SER B 2 160 ? 2.410   -43.108 -23.378 1.000 103.552 0 160 SER LLL CA  1 ? 
ATOM   2751 C C   . SER B 2 160 ? 3.549   -42.319 -24.035 1.000 111.012 0 160 SER LLL C   1 ? 
ATOM   2752 O O   . SER B 2 160 ? 4.087   -42.805 -25.059 1.000 114.623 0 160 SER LLL O   1 ? 
ATOM   2753 C CB  . SER B 2 160 ? 2.922   -44.092 -22.367 1.000 100.641 0 160 SER LLL CB  1 ? 
ATOM   2754 O OG  . SER B 2 160 ? 3.232   -43.433 -21.154 1.000 94.837  0 160 SER LLL OG  1 ? 
ATOM   2755 N N   . GLY B 2 161 ? 3.863   -41.137 -23.479 1.000 108.184 0 161 GLY LLL N   1 ? 
ATOM   2756 C CA  . GLY B 2 161 ? 4.976   -40.251 -23.888 1.000 98.383  0 161 GLY LLL CA  1 ? 
ATOM   2757 C C   . GLY B 2 161 ? 4.844   -39.714 -25.310 1.000 98.773  0 161 GLY LLL C   1 ? 
ATOM   2758 O O   . GLY B 2 161 ? 5.784   -39.043 -25.759 1.000 94.286  0 161 GLY LLL O   1 ? 
ATOM   2759 N N   . ASN B 2 162 ? 3.723   -39.969 -25.996 1.000 103.815 0 162 ASN LLL N   1 ? 
ATOM   2760 C CA  . ASN B 2 162 ? 3.479   -39.555 -27.407 1.000 109.681 0 162 ASN LLL CA  1 ? 
ATOM   2761 C C   . ASN B 2 162 ? 2.382   -38.482 -27.444 1.000 112.989 0 162 ASN LLL C   1 ? 
ATOM   2762 O O   . ASN B 2 162 ? 1.834   -38.215 -28.537 1.000 116.713 0 162 ASN LLL O   1 ? 
ATOM   2763 C CB  . ASN B 2 162 ? 3.136   -40.746 -28.311 1.000 112.208 0 162 ASN LLL CB  1 ? 
ATOM   2764 C CG  . ASN B 2 162 ? 2.244   -41.782 -27.660 1.000 115.668 0 162 ASN LLL CG  1 ? 
ATOM   2765 O OD1 . ASN B 2 162 ? 1.590   -41.527 -26.651 1.000 130.938 0 162 ASN LLL OD1 1 ? 
ATOM   2766 N ND2 . ASN B 2 162 ? 2.217   -42.969 -28.235 1.000 128.423 0 162 ASN LLL ND2 1 ? 
ATOM   2767 N N   . SER B 2 163 ? 2.086   -37.873 -26.294 1.000 107.749 0 163 SER LLL N   1 ? 
ATOM   2768 C CA  . SER B 2 163 ? 1.044   -36.831 -26.137 1.000 104.919 0 163 SER LLL CA  1 ? 
ATOM   2769 C C   . SER B 2 163 ? 1.537   -35.779 -25.142 1.000 97.971  0 163 SER LLL C   1 ? 
ATOM   2770 O O   . SER B 2 163 ? 2.059   -36.179 -24.088 1.000 104.889 0 163 SER LLL O   1 ? 
ATOM   2771 C CB  . SER B 2 163 ? -0.260  -37.443 -25.704 1.000 104.370 0 163 SER LLL CB  1 ? 
ATOM   2772 O OG  . SER B 2 163 ? -0.078  -38.261 -24.559 1.000 107.224 0 163 SER LLL OG  1 ? 
ATOM   2773 N N   . GLN B 2 164 ? 1.409   -34.499 -25.500 1.000 91.102  0 164 GLN LLL N   1 ? 
ATOM   2774 C CA  . GLN B 2 164 ? 1.573   -33.331 -24.592 1.000 95.223  0 164 GLN LLL CA  1 ? 
ATOM   2775 C C   . GLN B 2 164 ? 0.169   -32.774 -24.309 1.000 100.379 0 164 GLN LLL C   1 ? 
ATOM   2776 O O   . GLN B 2 164 ? -0.791  -33.201 -25.003 1.000 101.862 0 164 GLN LLL O   1 ? 
ATOM   2777 C CB  . GLN B 2 164 ? 2.525   -32.295 -25.201 1.000 83.387  0 164 GLN LLL CB  1 ? 
ATOM   2778 N N   . GLU B 2 165 ? 0.041   -31.898 -23.306 1.000 94.316  0 165 GLU LLL N   1 ? 
ATOM   2779 C CA  . GLU B 2 165 ? -1.259  -31.322 -22.863 1.000 91.905  0 165 GLU LLL CA  1 ? 
ATOM   2780 C C   . GLU B 2 165 ? -1.046  -29.903 -22.334 1.000 85.010  0 165 GLU LLL C   1 ? 
ATOM   2781 O O   . GLU B 2 165 ? -0.036  -29.651 -21.674 1.000 86.173  0 165 GLU LLL O   1 ? 
ATOM   2782 C CB  . GLU B 2 165 ? -1.948  -32.176 -21.793 1.000 94.024  0 165 GLU LLL CB  1 ? 
ATOM   2783 C CG  . GLU B 2 165 ? -1.024  -32.690 -20.705 1.000 103.003 0 165 GLU LLL CG  1 ? 
ATOM   2784 C CD  . GLU B 2 165 ? -1.677  -32.918 -19.349 1.000 102.218 0 165 GLU LLL CD  1 ? 
ATOM   2785 O OE1 . GLU B 2 165 ? -1.925  -34.091 -18.991 1.000 94.448  0 165 GLU LLL OE1 1 ? 
ATOM   2786 O OE2 . GLU B 2 165 ? -1.920  -31.919 -18.644 1.000 115.081 0 165 GLU LLL OE2 1 ? 
ATOM   2787 N N   . SER B 2 166 ? -1.984  -29.020 -22.654 1.000 82.743  0 166 SER LLL N   1 ? 
ATOM   2788 C CA  . SER B 2 166 ? -2.089  -27.631 -22.157 1.000 77.575  0 166 SER LLL CA  1 ? 
ATOM   2789 C C   . SER B 2 166 ? -3.394  -27.543 -21.373 1.000 75.750  0 166 SER LLL C   1 ? 
ATOM   2790 O O   . SER B 2 166 ? -4.266  -28.402 -21.614 1.000 76.684  0 166 SER LLL O   1 ? 
ATOM   2791 C CB  . SER B 2 166 ? -2.052  -26.657 -23.304 1.000 80.537  0 166 SER LLL CB  1 ? 
ATOM   2792 O OG  . SER B 2 166 ? -2.005  -25.325 -22.831 1.000 76.312  0 166 SER LLL OG  1 ? 
ATOM   2793 N N   . VAL B 2 167 ? -3.509  -26.558 -20.480 1.000 76.887  0 167 VAL LLL N   1 ? 
ATOM   2794 C CA  . VAL B 2 167 ? -4.694  -26.334 -19.596 1.000 72.143  0 167 VAL LLL CA  1 ? 
ATOM   2795 C C   . VAL B 2 167 ? -4.984  -24.837 -19.546 1.000 72.848  0 167 VAL LLL C   1 ? 
ATOM   2796 O O   . VAL B 2 167 ? -4.029  -24.051 -19.360 1.000 71.001  0 167 VAL LLL O   1 ? 
ATOM   2797 C CB  . VAL B 2 167 ? -4.456  -26.863 -18.172 1.000 68.521  0 167 VAL LLL CB  1 ? 
ATOM   2798 C CG1 . VAL B 2 167 ? -5.699  -26.727 -17.312 1.000 66.701  0 167 VAL LLL CG1 1 ? 
ATOM   2799 C CG2 . VAL B 2 167 ? -3.958  -28.298 -18.192 1.000 70.642  0 167 VAL LLL CG2 1 ? 
ATOM   2800 N N   . THR B 2 168 ? -6.252  -24.461 -19.674 1.000 71.887  0 168 THR LLL N   1 ? 
ATOM   2801 C CA  . THR B 2 168 ? -6.674  -23.044 -19.635 1.000 76.658  0 168 THR LLL CA  1 ? 
ATOM   2802 C C   . THR B 2 168 ? -6.527  -22.554 -18.195 1.000 81.588  0 168 THR LLL C   1 ? 
ATOM   2803 O O   . THR B 2 168 ? -6.684  -23.379 -17.284 1.000 72.411  0 168 THR LLL O   1 ? 
ATOM   2804 C CB  . THR B 2 168 ? -8.096  -22.856 -20.177 1.000 79.571  0 168 THR LLL CB  1 ? 
ATOM   2805 O OG1 . THR B 2 168 ? -9.038  -23.470 -19.295 1.000 86.633  0 168 THR LLL OG1 1 ? 
ATOM   2806 C CG2 . THR B 2 168 ? -8.255  -23.413 -21.572 1.000 80.057  0 168 THR LLL CG2 1 ? 
ATOM   2807 N N   . GLU B 2 169 ? -6.223  -21.266 -18.003 1.000 92.823  0 169 GLU LLL N   1 ? 
ATOM   2808 C CA  . GLU B 2 169 ? -6.362  -20.589 -16.684 1.000 97.742  0 169 GLU LLL CA  1 ? 
ATOM   2809 C C   . GLU B 2 169 ? -7.832  -20.718 -16.256 1.000 100.492 0 169 GLU LLL C   1 ? 
ATOM   2810 O O   . GLU B 2 169 ? -8.712  -20.425 -17.098 1.000 99.005  0 169 GLU LLL O   1 ? 
ATOM   2811 C CB  . GLU B 2 169 ? -5.912  -19.124 -16.760 1.000 86.515  0 169 GLU LLL CB  1 ? 
ATOM   2812 N N   . GLN B 2 170 ? -8.084  -21.190 -15.027 1.000 96.983  0 170 GLN LLL N   1 ? 
ATOM   2813 C CA  . GLN B 2 170 ? -9.434  -21.269 -14.400 1.000 100.610 0 170 GLN LLL CA  1 ? 
ATOM   2814 C C   . GLN B 2 170 ? -10.250 -20.014 -14.774 1.000 102.640 0 170 GLN LLL C   1 ? 
ATOM   2815 O O   . GLN B 2 170 ? -9.726  -18.887 -14.628 1.000 97.468  0 170 GLN LLL O   1 ? 
ATOM   2816 C CB  . GLN B 2 170 ? -9.281  -21.457 -12.884 1.000 109.249 0 170 GLN LLL CB  1 ? 
ATOM   2817 C CG  . GLN B 2 170 ? -10.412 -20.847 -12.059 1.000 116.527 0 170 GLN LLL CG  1 ? 
ATOM   2818 C CD  . GLN B 2 170 ? -10.484 -21.350 -10.636 1.000 112.407 0 170 GLN LLL CD  1 ? 
ATOM   2819 O OE1 . GLN B 2 170 ? -10.496 -20.567 -9.692  1.000 126.735 0 170 GLN LLL OE1 1 ? 
ATOM   2820 N NE2 . GLN B 2 170 ? -10.569 -22.661 -10.466 1.000 110.415 0 170 GLN LLL NE2 1 ? 
ATOM   2821 N N   . ASP B 2 171 ? -11.489 -20.192 -15.245 1.000 101.553 0 171 ASP LLL N   1 ? 
ATOM   2822 C CA  . ASP B 2 171 ? -12.362 -19.075 -15.697 1.000 104.050 0 171 ASP LLL CA  1 ? 
ATOM   2823 C C   . ASP B 2 171 ? -12.717 -18.200 -14.494 1.000 106.117 0 171 ASP LLL C   1 ? 
ATOM   2824 O O   . ASP B 2 171 ? -12.965 -18.757 -13.402 1.000 111.049 0 171 ASP LLL O   1 ? 
ATOM   2825 C CB  . ASP B 2 171 ? -13.650 -19.566 -16.360 1.000 111.818 0 171 ASP LLL CB  1 ? 
ATOM   2826 C CG  . ASP B 2 171 ? -14.409 -18.466 -17.089 1.000 113.223 0 171 ASP LLL CG  1 ? 
ATOM   2827 O OD1 . ASP B 2 171 ? -13.948 -18.056 -18.169 1.000 112.676 0 171 ASP LLL OD1 1 ? 
ATOM   2828 O OD2 . ASP B 2 171 ? -15.445 -18.017 -16.567 1.000 116.214 0 171 ASP LLL OD2 1 ? 
ATOM   2829 N N   . SER B 2 172 ? -12.737 -16.883 -14.703 1.000 108.649 0 172 SER LLL N   1 ? 
ATOM   2830 C CA  . SER B 2 172 ? -13.081 -15.868 -13.675 1.000 115.135 0 172 SER LLL CA  1 ? 
ATOM   2831 C C   . SER B 2 172 ? -14.463 -16.175 -13.081 1.000 113.475 0 172 SER LLL C   1 ? 
ATOM   2832 O O   . SER B 2 172 ? -14.543 -16.274 -11.842 1.000 119.437 0 172 SER LLL O   1 ? 
ATOM   2833 C CB  . SER B 2 172 ? -13.017 -14.473 -14.242 1.000 116.096 0 172 SER LLL CB  1 ? 
ATOM   2834 O OG  . SER B 2 172 ? -13.870 -14.352 -15.367 1.000 119.766 0 172 SER LLL OG  1 ? 
ATOM   2835 N N   . LYS B 2 173 ? -15.489 -16.355 -13.927 1.000 105.484 0 173 LYS LLL N   1 ? 
ATOM   2836 C CA  . LYS B 2 173 ? -16.911 -16.526 -13.508 1.000 105.717 0 173 LYS LLL CA  1 ? 
ATOM   2837 C C   . LYS B 2 173 ? -17.133 -17.931 -12.920 1.000 109.621 0 173 LYS LLL C   1 ? 
ATOM   2838 O O   . LYS B 2 173 ? -17.275 -18.042 -11.694 1.000 113.298 0 173 LYS LLL O   1 ? 
ATOM   2839 C CB  . LYS B 2 173 ? -17.855 -16.258 -14.688 1.000 97.410  0 173 LYS LLL CB  1 ? 
ATOM   2840 N N   . ASP B 2 174 ? -17.159 -18.974 -13.751 1.000 108.208 0 174 ASP LLL N   1 ? 
ATOM   2841 C CA  . ASP B 2 174 ? -17.648 -20.320 -13.348 1.000 103.061 0 174 ASP LLL CA  1 ? 
ATOM   2842 C C   . ASP B 2 174 ? -16.518 -21.191 -12.773 1.000 91.574  0 174 ASP LLL C   1 ? 
ATOM   2843 O O   . ASP B 2 174 ? -16.790 -22.378 -12.512 1.000 83.833  0 174 ASP LLL O   1 ? 
ATOM   2844 C CB  . ASP B 2 174 ? -18.325 -21.008 -14.534 1.000 112.060 0 174 ASP LLL CB  1 ? 
ATOM   2845 C CG  . ASP B 2 174 ? -17.378 -21.276 -15.684 1.000 113.415 0 174 ASP LLL CG  1 ? 
ATOM   2846 O OD1 . ASP B 2 174 ? -16.167 -21.059 -15.497 1.000 119.208 0 174 ASP LLL OD1 1 ? 
ATOM   2847 O OD2 . ASP B 2 174 ? -17.857 -21.698 -16.750 1.000 115.705 0 174 ASP LLL OD2 1 ? 
ATOM   2848 N N   . SER B 2 175 ? -15.298 -20.667 -12.623 1.000 86.778  0 175 SER LLL N   1 ? 
ATOM   2849 C CA  . SER B 2 175 ? -14.112 -21.409 -12.101 1.000 91.459  0 175 SER LLL CA  1 ? 
ATOM   2850 C C   . SER B 2 175 ? -13.758 -22.646 -12.951 1.000 89.926  0 175 SER LLL C   1 ? 
ATOM   2851 O O   . SER B 2 175 ? -12.983 -23.504 -12.455 1.000 79.258  0 175 SER LLL O   1 ? 
ATOM   2852 C CB  . SER B 2 175 ? -14.302 -21.816 -10.645 1.000 99.345  0 175 SER LLL CB  1 ? 
ATOM   2853 O OG  . SER B 2 175 ? -13.877 -20.775 -9.782  1.000 111.652 0 175 SER LLL OG  1 ? 
ATOM   2854 N N   . THR B 2 176 ? -14.251 -22.757 -14.184 1.000 94.927  0 176 THR LLL N   1 ? 
ATOM   2855 C CA  . THR B 2 176 ? -14.063 -23.991 -14.994 1.000 91.922  0 176 THR LLL CA  1 ? 
ATOM   2856 C C   . THR B 2 176 ? -12.696 -23.959 -15.674 1.000 85.612  0 176 THR LLL C   1 ? 
ATOM   2857 O O   . THR B 2 176 ? -12.207 -22.885 -16.024 1.000 86.624  0 176 THR LLL O   1 ? 
ATOM   2858 C CB  . THR B 2 176 ? -15.180 -24.199 -16.022 1.000 95.438  0 176 THR LLL CB  1 ? 
ATOM   2859 O OG1 . THR B 2 176 ? -15.252 -23.042 -16.856 1.000 105.496 0 176 THR LLL OG1 1 ? 
ATOM   2860 C CG2 . THR B 2 176 ? -16.518 -24.471 -15.372 1.000 97.610  0 176 THR LLL CG2 1 ? 
ATOM   2861 N N   . TYR B 2 177 ? -12.118 -25.129 -15.875 1.000 93.998  0 177 TYR LLL N   1 ? 
ATOM   2862 C CA  . TYR B 2 177 ? -10.866 -25.314 -16.639 1.000 87.628  0 177 TYR LLL CA  1 ? 
ATOM   2863 C C   . TYR B 2 177 ? -11.204 -26.007 -17.954 1.000 82.301  0 177 TYR LLL C   1 ? 
ATOM   2864 O O   . TYR B 2 177 ? -12.244 -26.675 -18.061 1.000 79.948  0 177 TYR LLL O   1 ? 
ATOM   2865 C CB  . TYR B 2 177 ? -9.892  -26.200 -15.870 1.000 87.195  0 177 TYR LLL CB  1 ? 
ATOM   2866 C CG  . TYR B 2 177 ? -9.465  -25.716 -14.509 1.000 94.675  0 177 TYR LLL CG  1 ? 
ATOM   2867 C CD1 . TYR B 2 177 ? -10.242 -25.942 -13.383 1.000 99.775  0 177 TYR LLL CD1 1 ? 
ATOM   2868 C CD2 . TYR B 2 177 ? -8.232  -25.104 -14.333 1.000 99.198  0 177 TYR LLL CD2 1 ? 
ATOM   2869 C CE1 . TYR B 2 177 ? -9.817  -25.544 -12.123 1.000 102.841 0 177 TYR LLL CE1 1 ? 
ATOM   2870 C CE2 . TYR B 2 177 ? -7.791  -24.703 -13.083 1.000 99.228  0 177 TYR LLL CE2 1 ? 
ATOM   2871 C CZ  . TYR B 2 177 ? -8.584  -24.926 -11.973 1.000 104.361 0 177 TYR LLL CZ  1 ? 
ATOM   2872 O OH  . TYR B 2 177 ? -8.131  -24.512 -10.754 1.000 103.512 0 177 TYR LLL OH  1 ? 
ATOM   2873 N N   . SER B 2 178 ? -10.305 -25.916 -18.917 1.000 72.965  0 178 SER LLL N   1 ? 
ATOM   2874 C CA  . SER B 2 178 ? -10.341 -26.771 -20.121 1.000 65.336  0 178 SER LLL CA  1 ? 
ATOM   2875 C C   . SER B 2 178 ? -8.947  -27.324 -20.370 1.000 59.753  0 178 SER LLL C   1 ? 
ATOM   2876 O O   . SER B 2 178 ? -7.962  -26.650 -20.053 1.000 53.732  0 178 SER LLL O   1 ? 
ATOM   2877 C CB  . SER B 2 178 ? -10.892 -26.039 -21.295 1.000 63.412  0 178 SER LLL CB  1 ? 
ATOM   2878 O OG  . SER B 2 178 ? -12.262 -25.756 -21.087 1.000 63.828  0 178 SER LLL OG  1 ? 
ATOM   2879 N N   . LEU B 2 179 ? -8.896  -28.547 -20.871 1.000 68.751  0 179 LEU LLL N   1 ? 
ATOM   2880 C CA  . LEU B 2 179 ? -7.635  -29.257 -21.164 1.000 76.074  0 179 LEU LLL CA  1 ? 
ATOM   2881 C C   . LEU B 2 179 ? -7.662  -29.713 -22.623 1.000 75.191  0 179 LEU LLL C   1 ? 
ATOM   2882 O O   . LEU B 2 179 ? -8.726  -30.163 -23.070 1.000 74.476  0 179 LEU LLL O   1 ? 
ATOM   2883 C CB  . LEU B 2 179 ? -7.515  -30.430 -20.191 1.000 80.756  0 179 LEU LLL CB  1 ? 
ATOM   2884 C CG  . LEU B 2 179 ? -6.261  -31.278 -20.374 1.000 89.747  0 179 LEU LLL CG  1 ? 
ATOM   2885 C CD1 . LEU B 2 179 ? -5.584  -31.537 -19.041 1.000 88.559  0 179 LEU LLL CD1 1 ? 
ATOM   2886 C CD2 . LEU B 2 179 ? -6.592  -32.583 -21.085 1.000 90.190  0 179 LEU LLL CD2 1 ? 
ATOM   2887 N N   . SER B 2 180 ? -6.534  -29.586 -23.324 1.000 81.983  0 180 SER LLL N   1 ? 
ATOM   2888 C CA  . SER B 2 180 ? -6.342  -30.087 -24.711 1.000 93.032  0 180 SER LLL CA  1 ? 
ATOM   2889 C C   . SER B 2 180 ? -5.075  -30.944 -24.777 1.000 89.868  0 180 SER LLL C   1 ? 
ATOM   2890 O O   . SER B 2 180 ? -3.972  -30.384 -24.643 1.000 96.683  0 180 SER LLL O   1 ? 
ATOM   2891 C CB  . SER B 2 180 ? -6.294  -28.953 -25.705 1.000 90.274  0 180 SER LLL CB  1 ? 
ATOM   2892 O OG  . SER B 2 180 ? -5.260  -28.041 -25.373 1.000 96.065  0 180 SER LLL OG  1 ? 
ATOM   2893 N N   . SER B 2 181 ? -5.233  -32.251 -24.990 1.000 87.114  0 181 SER LLL N   1 ? 
ATOM   2894 C CA  . SER B 2 181 ? -4.106  -33.199 -25.183 1.000 90.762  0 181 SER LLL CA  1 ? 
ATOM   2895 C C   . SER B 2 181 ? -3.909  -33.512 -26.667 1.000 87.148  0 181 SER LLL C   1 ? 
ATOM   2896 O O   . SER B 2 181 ? -4.876  -33.899 -27.330 1.000 75.848  0 181 SER LLL O   1 ? 
ATOM   2897 C CB  . SER B 2 181 ? -4.301  -34.456 -24.423 1.000 89.186  0 181 SER LLL CB  1 ? 
ATOM   2898 O OG  . SER B 2 181 ? -3.059  -35.130 -24.342 1.000 95.393  0 181 SER LLL OG  1 ? 
ATOM   2899 N N   . THR B 2 182 ? -2.682  -33.371 -27.156 1.000 90.440  0 182 THR LLL N   1 ? 
ATOM   2900 C CA  . THR B 2 182 ? -2.350  -33.561 -28.587 1.000 100.429 0 182 THR LLL CA  1 ? 
ATOM   2901 C C   . THR B 2 182 ? -1.481  -34.813 -28.720 1.000 103.103 0 182 THR LLL C   1 ? 
ATOM   2902 O O   . THR B 2 182 ? -0.257  -34.718 -28.496 1.000 107.704 0 182 THR LLL O   1 ? 
ATOM   2903 C CB  . THR B 2 182 ? -1.699  -32.300 -29.168 1.000 105.468 0 182 THR LLL CB  1 ? 
ATOM   2904 O OG1 . THR B 2 182 ? -2.477  -31.166 -28.772 1.000 103.633 0 182 THR LLL OG1 1 ? 
ATOM   2905 C CG2 . THR B 2 182 ? -1.584  -32.361 -30.675 1.000 101.167 0 182 THR LLL CG2 1 ? 
ATOM   2906 N N   . LEU B 2 183 ? -2.103  -35.946 -29.044 1.000 100.294 0 183 LEU LLL N   1 ? 
ATOM   2907 C CA  . LEU B 2 183 ? -1.391  -37.199 -29.395 1.000 98.422  0 183 LEU LLL CA  1 ? 
ATOM   2908 C C   . LEU B 2 183 ? -0.836  -37.042 -30.806 1.000 102.245 0 183 LEU LLL C   1 ? 
ATOM   2909 O O   . LEU B 2 183 ? -1.640  -36.826 -31.734 1.000 101.294 0 183 LEU LLL O   1 ? 
ATOM   2910 C CB  . LEU B 2 183 ? -2.358  -38.379 -29.338 1.000 99.959  0 183 LEU LLL CB  1 ? 
ATOM   2911 C CG  . LEU B 2 183 ? -1.716  -39.741 -29.577 1.000 95.814  0 183 LEU LLL CG  1 ? 
ATOM   2912 C CD1 . LEU B 2 183 ? -1.094  -40.261 -28.295 1.000 95.909  0 183 LEU LLL CD1 1 ? 
ATOM   2913 C CD2 . LEU B 2 183 ? -2.736  -40.728 -30.114 1.000 101.444 0 183 LEU LLL CD2 1 ? 
ATOM   2914 N N   . THR B 2 184 ? 0.484   -37.131 -30.945 1.000 108.837 0 184 THR LLL N   1 ? 
ATOM   2915 C CA  . THR B 2 184 ? 1.208   -36.921 -32.225 1.000 114.040 0 184 THR LLL CA  1 ? 
ATOM   2916 C C   . THR B 2 184 ? 1.838   -38.250 -32.642 1.000 110.815 0 184 THR LLL C   1 ? 
ATOM   2917 O O   . THR B 2 184 ? 2.416   -38.923 -31.779 1.000 104.424 0 184 THR LLL O   1 ? 
ATOM   2918 C CB  . THR B 2 184 ? 2.241   -35.798 -32.091 1.000 116.650 0 184 THR LLL CB  1 ? 
ATOM   2919 O OG1 . THR B 2 184 ? 3.335   -36.313 -31.334 1.000 125.015 0 184 THR LLL OG1 1 ? 
ATOM   2920 C CG2 . THR B 2 184 ? 1.686   -34.562 -31.416 1.000 118.388 0 184 THR LLL CG2 1 ? 
ATOM   2921 N N   . LEU B 2 185 ? 1.688   -38.622 -33.910 1.000 121.168 0 185 LEU LLL N   1 ? 
ATOM   2922 C CA  . LEU B 2 185 ? 2.249   -39.870 -34.490 1.000 131.373 0 185 LEU LLL CA  1 ? 
ATOM   2923 C C   . LEU B 2 185 ? 2.783   -39.555 -35.893 1.000 140.654 0 185 LEU LLL C   1 ? 
ATOM   2924 O O   . LEU B 2 185 ? 2.628   -38.407 -36.329 1.000 156.164 0 185 LEU LLL O   1 ? 
ATOM   2925 C CB  . LEU B 2 185 ? 1.143   -40.932 -34.527 1.000 129.700 0 185 LEU LLL CB  1 ? 
ATOM   2926 C CG  . LEU B 2 185 ? 0.762   -41.570 -33.190 1.000 124.676 0 185 LEU LLL CG  1 ? 
ATOM   2927 C CD1 . LEU B 2 185 ? -0.410  -42.520 -33.383 1.000 121.750 0 185 LEU LLL CD1 1 ? 
ATOM   2928 C CD2 . LEU B 2 185 ? 1.941   -42.303 -32.552 1.000 124.703 0 185 LEU LLL CD2 1 ? 
ATOM   2929 N N   . SER B 2 186 ? 3.404   -40.524 -36.570 1.000 140.665 0 186 SER LLL N   1 ? 
ATOM   2930 C CA  . SER B 2 186 ? 3.769   -40.422 -38.008 1.000 138.372 0 186 SER LLL CA  1 ? 
ATOM   2931 C C   . SER B 2 186 ? 2.558   -40.829 -38.859 1.000 128.144 0 186 SER LLL C   1 ? 
ATOM   2932 O O   . SER B 2 186 ? 1.685   -41.563 -38.327 1.000 111.789 0 186 SER LLL O   1 ? 
ATOM   2933 C CB  . SER B 2 186 ? 4.985   -41.256 -38.316 1.000 139.598 0 186 SER LLL CB  1 ? 
ATOM   2934 O OG  . SER B 2 186 ? 4.637   -42.618 -38.506 1.000 139.478 0 186 SER LLL OG  1 ? 
ATOM   2935 N N   . LYS B 2 187 ? 2.488   -40.356 -40.112 1.000 123.270 0 187 LYS LLL N   1 ? 
ATOM   2936 C CA  . LYS B 2 187 ? 1.432   -40.760 -41.084 1.000 125.008 0 187 LYS LLL CA  1 ? 
ATOM   2937 C C   . LYS B 2 187 ? 1.419   -42.291 -41.156 1.000 135.306 0 187 LYS LLL C   1 ? 
ATOM   2938 O O   . LYS B 2 187 ? 0.326   -42.867 -41.291 1.000 143.145 0 187 LYS LLL O   1 ? 
ATOM   2939 C CB  . LYS B 2 187 ? 1.643   -40.134 -42.467 1.000 113.244 0 187 LYS LLL CB  1 ? 
ATOM   2940 N N   . ALA B 2 188 ? 2.593   -42.919 -41.029 1.000 143.922 0 188 ALA LLL N   1 ? 
ATOM   2941 C CA  . ALA B 2 188 ? 2.762   -44.389 -40.947 1.000 144.362 0 188 ALA LLL CA  1 ? 
ATOM   2942 C C   . ALA B 2 188 ? 2.071   -44.910 -39.681 1.000 144.543 0 188 ALA LLL C   1 ? 
ATOM   2943 O O   . ALA B 2 188 ? 1.138   -45.729 -39.811 1.000 141.283 0 188 ALA LLL O   1 ? 
ATOM   2944 C CB  . ALA B 2 188 ? 4.229   -44.750 -40.967 1.000 144.813 0 188 ALA LLL CB  1 ? 
ATOM   2945 N N   . ASP B 2 189 ? 2.490   -44.423 -38.508 1.000 134.241 0 189 ASP LLL N   1 ? 
ATOM   2946 C CA  . ASP B 2 189 ? 1.960   -44.870 -37.192 1.000 123.409 0 189 ASP LLL CA  1 ? 
ATOM   2947 C C   . ASP B 2 189 ? 0.464   -44.545 -37.099 1.000 123.760 0 189 ASP LLL C   1 ? 
ATOM   2948 O O   . ASP B 2 189 ? -0.150  -44.994 -36.114 1.000 119.799 0 189 ASP LLL O   1 ? 
ATOM   2949 C CB  . ASP B 2 189 ? 2.714   -44.228 -36.023 1.000 117.791 0 189 ASP LLL CB  1 ? 
ATOM   2950 C CG  . ASP B 2 189 ? 4.189   -44.575 -35.967 1.000 116.275 0 189 ASP LLL CG  1 ? 
ATOM   2951 O OD1 . ASP B 2 189 ? 4.559   -45.628 -36.512 1.000 116.508 0 189 ASP LLL OD1 1 ? 
ATOM   2952 O OD2 . ASP B 2 189 ? 4.955   -43.784 -35.383 1.000 113.377 0 189 ASP LLL OD2 1 ? 
ATOM   2953 N N   . TYR B 2 190 ? -0.094  -43.794 -38.062 1.000 124.128 0 190 TYR LLL N   1 ? 
ATOM   2954 C CA  . TYR B 2 190 ? -1.535  -43.418 -38.097 1.000 126.169 0 190 TYR LLL CA  1 ? 
ATOM   2955 C C   . TYR B 2 190 ? -2.323  -44.389 -38.993 1.000 130.478 0 190 TYR LLL C   1 ? 
ATOM   2956 O O   . TYR B 2 190 ? -3.389  -44.885 -38.562 1.000 119.060 0 190 TYR LLL O   1 ? 
ATOM   2957 C CB  . TYR B 2 190 ? -1.741  -41.961 -38.532 1.000 117.405 0 190 TYR LLL CB  1 ? 
ATOM   2958 C CG  . TYR B 2 190 ? -3.191  -41.533 -38.565 1.000 111.340 0 190 TYR LLL CG  1 ? 
ATOM   2959 C CD1 . TYR B 2 190 ? -3.882  -41.235 -37.400 1.000 104.321 0 190 TYR LLL CD1 1 ? 
ATOM   2960 C CD2 . TYR B 2 190 ? -3.892  -41.456 -39.762 1.000 107.087 0 190 TYR LLL CD2 1 ? 
ATOM   2961 C CE1 . TYR B 2 190 ? -5.220  -40.864 -37.426 1.000 101.139 0 190 TYR LLL CE1 1 ? 
ATOM   2962 C CE2 . TYR B 2 190 ? -5.229  -41.087 -39.805 1.000 99.898  0 190 TYR LLL CE2 1 ? 
ATOM   2963 C CZ  . TYR B 2 190 ? -5.898  -40.785 -38.633 1.000 100.114 0 190 TYR LLL CZ  1 ? 
ATOM   2964 O OH  . TYR B 2 190 ? -7.218  -40.428 -38.681 1.000 95.901  0 190 TYR LLL OH  1 ? 
ATOM   2965 N N   . GLU B 2 191 ? -1.834  -44.665 -40.205 1.000 133.504 0 191 GLU LLL N   1 ? 
ATOM   2966 C CA  . GLU B 2 191 ? -2.531  -45.573 -41.156 1.000 135.434 0 191 GLU LLL CA  1 ? 
ATOM   2967 C C   . GLU B 2 191 ? -2.388  -47.023 -40.665 1.000 135.881 0 191 GLU LLL C   1 ? 
ATOM   2968 O O   . GLU B 2 191 ? -2.856  -47.921 -41.377 1.000 138.651 0 191 GLU LLL O   1 ? 
ATOM   2969 C CB  . GLU B 2 191 ? -2.002  -45.379 -42.580 1.000 134.707 0 191 GLU LLL CB  1 ? 
ATOM   2970 N N   . LYS B 2 192 ? -1.787  -47.238 -39.486 1.000 137.459 0 192 LYS LLL N   1 ? 
ATOM   2971 C CA  . LYS B 2 192 ? -1.524  -48.579 -38.891 1.000 127.863 0 192 LYS LLL CA  1 ? 
ATOM   2972 C C   . LYS B 2 192 ? -2.713  -49.050 -38.035 1.000 131.254 0 192 LYS LLL C   1 ? 
ATOM   2973 O O   . LYS B 2 192 ? -2.939  -50.271 -37.985 1.000 131.978 0 192 LYS LLL O   1 ? 
ATOM   2974 C CB  . LYS B 2 192 ? -0.232  -48.544 -38.066 1.000 116.707 0 192 LYS LLL CB  1 ? 
ATOM   2975 N N   . HIS B 2 193 ? -3.451  -48.145 -37.381 1.000 130.299 0 193 HIS LLL N   1 ? 
ATOM   2976 C CA  . HIS B 2 193 ? -4.536  -48.505 -36.423 1.000 120.088 0 193 HIS LLL CA  1 ? 
ATOM   2977 C C   . HIS B 2 193 ? -5.896  -48.004 -36.942 1.000 120.747 0 193 HIS LLL C   1 ? 
ATOM   2978 O O   . HIS B 2 193 ? -5.905  -47.352 -38.001 1.000 119.974 0 193 HIS LLL O   1 ? 
ATOM   2979 C CB  . HIS B 2 193 ? -4.159  -48.004 -35.027 1.000 116.399 0 193 HIS LLL CB  1 ? 
ATOM   2980 C CG  . HIS B 2 193 ? -2.749  -48.305 -34.638 1.000 108.752 0 193 HIS LLL CG  1 ? 
ATOM   2981 N ND1 . HIS B 2 193 ? -1.779  -47.324 -34.561 1.000 109.562 0 193 HIS LLL ND1 1 ? 
ATOM   2982 C CD2 . HIS B 2 193 ? -2.142  -49.459 -34.293 1.000 107.683 0 193 HIS LLL CD2 1 ? 
ATOM   2983 C CE1 . HIS B 2 193 ? -0.636  -47.859 -34.182 1.000 107.313 0 193 HIS LLL CE1 1 ? 
ATOM   2984 N NE2 . HIS B 2 193 ? -0.831  -49.169 -34.017 1.000 107.389 0 193 HIS LLL NE2 1 ? 
ATOM   2985 N N   . LYS B 2 194 ? -7.000  -48.319 -36.243 1.000 124.316 0 194 LYS LLL N   1 ? 
ATOM   2986 C CA  . LYS B 2 194 ? -8.402  -48.128 -36.735 1.000 133.536 0 194 LYS LLL CA  1 ? 
ATOM   2987 C C   . LYS B 2 194 ? -9.162  -47.117 -35.859 1.000 141.647 0 194 LYS LLL C   1 ? 
ATOM   2988 O O   . LYS B 2 194 ? -9.452  -45.997 -36.357 1.000 117.759 0 194 LYS LLL O   1 ? 
ATOM   2989 C CB  . LYS B 2 194 ? -9.157  -49.464 -36.781 1.000 116.277 0 194 LYS LLL CB  1 ? 
ATOM   2990 N N   . VAL B 2 195 ? -9.498  -47.511 -34.621 1.000 157.590 0 195 VAL LLL N   1 ? 
ATOM   2991 C CA  . VAL B 2 195 ? -10.300 -46.696 -33.655 1.000 148.057 0 195 VAL LLL CA  1 ? 
ATOM   2992 C C   . VAL B 2 195 ? -9.341  -45.968 -32.699 1.000 143.862 0 195 VAL LLL C   1 ? 
ATOM   2993 O O   . VAL B 2 195 ? -8.806  -46.595 -31.744 1.000 132.818 0 195 VAL LLL O   1 ? 
ATOM   2994 C CB  . VAL B 2 195 ? -11.378 -47.517 -32.910 1.000 143.224 0 195 VAL LLL CB  1 ? 
ATOM   2995 C CG1 . VAL B 2 195 ? -12.451 -48.014 -33.869 1.000 134.863 0 195 VAL LLL CG1 1 ? 
ATOM   2996 C CG2 . VAL B 2 195 ? -10.813 -48.673 -32.086 1.000 141.335 0 195 VAL LLL CG2 1 ? 
ATOM   2997 N N   . TYR B 2 196 ? -9.110  -44.686 -32.989 1.000 139.871 0 196 TYR LLL N   1 ? 
ATOM   2998 C CA  . TYR B 2 196 ? -8.422  -43.714 -32.102 1.000 136.748 0 196 TYR LLL CA  1 ? 
ATOM   2999 C C   . TYR B 2 196 ? -9.461  -43.164 -31.127 1.000 121.131 0 196 TYR LLL C   1 ? 
ATOM   3000 O O   . TYR B 2 196 ? -10.493 -42.642 -31.615 1.000 91.558  0 196 TYR LLL O   1 ? 
ATOM   3001 C CB  . TYR B 2 196 ? -7.742  -42.622 -32.932 1.000 143.134 0 196 TYR LLL CB  1 ? 
ATOM   3002 C CG  . TYR B 2 196 ? -6.614  -43.155 -33.774 1.000 140.169 0 196 TYR LLL CG  1 ? 
ATOM   3003 C CD1 . TYR B 2 196 ? -5.333  -43.276 -33.261 1.000 133.502 0 196 TYR LLL CD1 1 ? 
ATOM   3004 C CD2 . TYR B 2 196 ? -6.845  -43.616 -35.058 1.000 145.581 0 196 TYR LLL CD2 1 ? 
ATOM   3005 C CE1 . TYR B 2 196 ? -4.298  -43.793 -34.022 1.000 138.733 0 196 TYR LLL CE1 1 ? 
ATOM   3006 C CE2 . TYR B 2 196 ? -5.822  -44.142 -35.829 1.000 147.526 0 196 TYR LLL CE2 1 ? 
ATOM   3007 C CZ  . TYR B 2 196 ? -4.543  -44.236 -35.309 1.000 147.419 0 196 TYR LLL CZ  1 ? 
ATOM   3008 O OH  . TYR B 2 196 ? -3.530  -44.765 -36.058 1.000 166.800 0 196 TYR LLL OH  1 ? 
ATOM   3009 N N   . ALA B 2 197 ? -9.195  -43.314 -29.822 1.000 118.522 0 197 ALA LLL N   1 ? 
ATOM   3010 C CA  . ALA B 2 197 ? -10.135 -43.023 -28.714 1.000 120.638 0 197 ALA LLL CA  1 ? 
ATOM   3011 C C   . ALA B 2 197 ? -9.438  -42.228 -27.609 1.000 117.574 0 197 ALA LLL C   1 ? 
ATOM   3012 O O   . ALA B 2 197 ? -8.248  -41.882 -27.770 1.000 113.403 0 197 ALA LLL O   1 ? 
ATOM   3013 C CB  . ALA B 2 197 ? -10.709 -44.308 -28.169 1.000 126.465 0 197 ALA LLL CB  1 ? 
ATOM   3014 N N   . CYS B 2 198 ? -10.166 -41.989 -26.514 1.000 118.529 0 198 CYS LLL N   1 ? 
ATOM   3015 C CA  . CYS B 2 198 ? -9.812  -41.045 -25.423 1.000 116.145 0 198 CYS LLL CA  1 ? 
ATOM   3016 C C   . CYS B 2 198 ? -10.790 -41.236 -24.251 1.000 108.978 0 198 CYS LLL C   1 ? 
ATOM   3017 O O   . CYS B 2 198 ? -11.943 -40.753 -24.348 1.000 95.394  0 198 CYS LLL O   1 ? 
ATOM   3018 C CB  . CYS B 2 198 ? -9.844  -39.623 -25.973 1.000 116.780 0 198 CYS LLL CB  1 ? 
ATOM   3019 S SG  . CYS B 2 198 ? -9.209  -38.359 -24.845 1.000 125.771 0 198 CYS LLL SG  1 ? 
ATOM   3020 N N   . GLU B 2 199 ? -10.354 -41.953 -23.208 1.000 111.847 0 199 GLU LLL N   1 ? 
ATOM   3021 C CA  . GLU B 2 199 ? -11.151 -42.250 -21.988 1.000 110.322 0 199 GLU LLL CA  1 ? 
ATOM   3022 C C   . GLU B 2 199 ? -10.943 -41.113 -20.986 1.000 100.970 0 199 GLU LLL C   1 ? 
ATOM   3023 O O   . GLU B 2 199 ? -9.778  -40.806 -20.686 1.000 98.640  0 199 GLU LLL O   1 ? 
ATOM   3024 C CB  . GLU B 2 199 ? -10.735 -43.585 -21.360 1.000 120.235 0 199 GLU LLL CB  1 ? 
ATOM   3025 C CG  . GLU B 2 199 ? -11.552 -43.948 -20.128 1.000 123.549 0 199 GLU LLL CG  1 ? 
ATOM   3026 C CD  . GLU B 2 199 ? -11.255 -45.302 -19.507 1.000 128.939 0 199 GLU LLL CD  1 ? 
ATOM   3027 O OE1 . GLU B 2 199 ? -10.160 -45.837 -19.743 1.000 142.962 0 199 GLU LLL OE1 1 ? 
ATOM   3028 O OE2 . GLU B 2 199 ? -12.130 -45.821 -18.790 1.000 132.418 0 199 GLU LLL OE2 1 ? 
ATOM   3029 N N   . VAL B 2 200 ? -12.031 -40.531 -20.477 1.000 98.246  0 200 VAL LLL N   1 ? 
ATOM   3030 C CA  . VAL B 2 200 ? -11.989 -39.372 -19.534 1.000 89.192  0 200 VAL LLL CA  1 ? 
ATOM   3031 C C   . VAL B 2 200 ? -12.718 -39.734 -18.241 1.000 78.437  0 200 VAL LLL C   1 ? 
ATOM   3032 O O   . VAL B 2 200 ? -13.852 -40.234 -18.321 1.000 67.642  0 200 VAL LLL O   1 ? 
ATOM   3033 C CB  . VAL B 2 200 ? -12.592 -38.117 -20.182 1.000 88.341  0 200 VAL LLL CB  1 ? 
ATOM   3034 C CG1 . VAL B 2 200 ? -12.713 -36.967 -19.198 1.000 89.361  0 200 VAL LLL CG1 1 ? 
ATOM   3035 C CG2 . VAL B 2 200 ? -11.787 -37.700 -21.399 1.000 93.147  0 200 VAL LLL CG2 1 ? 
ATOM   3036 N N   . THR B 2 201 ? -12.061 -39.482 -17.109 1.000 77.158  0 201 THR LLL N   1 ? 
ATOM   3037 C CA  . THR B 2 201 ? -12.606 -39.657 -15.742 1.000 91.451  0 201 THR LLL CA  1 ? 
ATOM   3038 C C   . THR B 2 201 ? -12.569 -38.295 -15.048 1.000 90.012  0 201 THR LLL C   1 ? 
ATOM   3039 O O   . THR B 2 201 ? -11.614 -37.514 -15.290 1.000 79.535  0 201 THR LLL O   1 ? 
ATOM   3040 C CB  . THR B 2 201 ? -11.847 -40.737 -14.957 1.000 101.891 0 201 THR LLL CB  1 ? 
ATOM   3041 O OG1 . THR B 2 201 ? -11.750 -41.877 -15.809 1.000 112.212 0 201 THR LLL OG1 1 ? 
ATOM   3042 C CG2 . THR B 2 201 ? -12.510 -41.132 -13.653 1.000 106.723 0 201 THR LLL CG2 1 ? 
ATOM   3043 N N   . HIS B 2 202 ? -13.588 -38.053 -14.224 1.000 89.885  0 202 HIS LLL N   1 ? 
ATOM   3044 C CA  . HIS B 2 202 ? -13.837 -36.801 -13.475 1.000 87.671  0 202 HIS LLL CA  1 ? 
ATOM   3045 C C   . HIS B 2 202 ? -15.015 -37.053 -12.532 1.000 89.778  0 202 HIS LLL C   1 ? 
ATOM   3046 O O   . HIS B 2 202 ? -15.899 -37.840 -12.919 1.000 89.345  0 202 HIS LLL O   1 ? 
ATOM   3047 C CB  . HIS B 2 202 ? -14.097 -35.661 -14.463 1.000 82.834  0 202 HIS LLL CB  1 ? 
ATOM   3048 C CG  . HIS B 2 202 ? -14.176 -34.329 -13.814 1.000 76.320  0 202 HIS LLL CG  1 ? 
ATOM   3049 N ND1 . HIS B 2 202 ? -15.357 -33.809 -13.361 1.000 72.597  0 202 HIS LLL ND1 1 ? 
ATOM   3050 C CD2 . HIS B 2 202 ? -13.224 -33.417 -13.535 1.000 79.299  0 202 HIS LLL CD2 1 ? 
ATOM   3051 C CE1 . HIS B 2 202 ? -15.137 -32.624 -12.830 1.000 75.675  0 202 HIS LLL CE1 1 ? 
ATOM   3052 N NE2 . HIS B 2 202 ? -13.835 -32.358 -12.926 1.000 73.458  0 202 HIS LLL NE2 1 ? 
ATOM   3053 N N   . GLN B 2 203 ? -15.010 -36.442 -11.344 1.000 92.304  0 203 GLN LLL N   1 ? 
ATOM   3054 C CA  . GLN B 2 203 ? -16.130 -36.517 -10.365 1.000 92.603  0 203 GLN LLL CA  1 ? 
ATOM   3055 C C   . GLN B 2 203 ? -17.454 -36.367 -11.111 1.000 86.345  0 203 GLN LLL C   1 ? 
ATOM   3056 O O   . GLN B 2 203 ? -18.325 -37.226 -10.939 1.000 87.659  0 203 GLN LLL O   1 ? 
ATOM   3057 C CB  . GLN B 2 203 ? -16.056 -35.394 -9.332  1.000 102.483 0 203 GLN LLL CB  1 ? 
ATOM   3058 C CG  . GLN B 2 203 ? -15.273 -35.746 -8.077  1.000 111.224 0 203 GLN LLL CG  1 ? 
ATOM   3059 C CD  . GLN B 2 203 ? -14.990 -34.507 -7.263  1.000 111.923 0 203 GLN LLL CD  1 ? 
ATOM   3060 O OE1 . GLN B 2 203 ? -13.843 -34.205 -6.938  1.000 123.376 0 203 GLN LLL OE1 1 ? 
ATOM   3061 N NE2 . GLN B 2 203 ? -16.038 -33.760 -6.951  1.000 107.256 0 203 GLN LLL NE2 1 ? 
ATOM   3062 N N   . GLY B 2 204 ? -17.551 -35.311 -11.925 1.000 83.871  0 204 GLY LLL N   1 ? 
ATOM   3063 C CA  . GLY B 2 204 ? -18.756 -34.860 -12.648 1.000 80.910  0 204 GLY LLL CA  1 ? 
ATOM   3064 C C   . GLY B 2 204 ? -19.451 -35.980 -13.391 1.000 75.948  0 204 GLY LLL C   1 ? 
ATOM   3065 O O   . GLY B 2 204 ? -20.684 -35.981 -13.410 1.000 70.889  0 204 GLY LLL O   1 ? 
ATOM   3066 N N   . LEU B 2 205 ? -18.683 -36.892 -13.985 1.000 85.071  0 205 LEU LLL N   1 ? 
ATOM   3067 C CA  . LEU B 2 205 ? -19.197 -38.030 -14.791 1.000 87.076  0 205 LEU LLL CA  1 ? 
ATOM   3068 C C   . LEU B 2 205 ? -19.598 -39.164 -13.845 1.000 95.499  0 205 LEU LLL C   1 ? 
ATOM   3069 O O   . LEU B 2 205 ? -18.844 -39.418 -12.885 1.000 95.227  0 205 LEU LLL O   1 ? 
ATOM   3070 C CB  . LEU B 2 205 ? -18.093 -38.495 -15.745 1.000 90.372  0 205 LEU LLL CB  1 ? 
ATOM   3071 C CG  . LEU B 2 205 ? -17.490 -37.416 -16.644 1.000 92.599  0 205 LEU LLL CG  1 ? 
ATOM   3072 C CD1 . LEU B 2 205 ? -16.213 -37.920 -17.298 1.000 99.812  0 205 LEU LLL CD1 1 ? 
ATOM   3073 C CD2 . LEU B 2 205 ? -18.485 -36.951 -17.698 1.000 90.720  0 205 LEU LLL CD2 1 ? 
ATOM   3074 N N   . SER B 2 206 ? -20.729 -39.826 -14.105 1.000 104.288 0 206 SER LLL N   1 ? 
ATOM   3075 C CA  . SER B 2 206 ? -21.115 -41.102 -13.441 1.000 105.884 0 206 SER LLL CA  1 ? 
ATOM   3076 C C   . SER B 2 206 ? -20.003 -42.129 -13.670 1.000 107.211 0 206 SER LLL C   1 ? 
ATOM   3077 O O   . SER B 2 206 ? -19.279 -42.482 -12.708 1.000 95.677  0 206 SER LLL O   1 ? 
ATOM   3078 C CB  . SER B 2 206 ? -22.433 -41.620 -13.959 1.000 100.035 0 206 SER LLL CB  1 ? 
ATOM   3079 O OG  . SER B 2 206 ? -22.555 -41.380 -15.352 1.000 95.720  0 206 SER LLL OG  1 ? 
ATOM   3080 N N   . SER B 2 207 ? -19.868 -42.545 -14.928 1.000 112.599 0 207 SER LLL N   1 ? 
ATOM   3081 C CA  . SER B 2 207 ? -18.869 -43.519 -15.427 1.000 114.665 0 207 SER LLL CA  1 ? 
ATOM   3082 C C   . SER B 2 207 ? -17.930 -42.806 -16.397 1.000 110.320 0 207 SER LLL C   1 ? 
ATOM   3083 O O   . SER B 2 207 ? -18.336 -41.852 -17.064 1.000 110.237 0 207 SER LLL O   1 ? 
ATOM   3084 C CB  . SER B 2 207 ? -19.570 -44.677 -16.081 1.000 118.354 0 207 SER LLL CB  1 ? 
ATOM   3085 O OG  . SER B 2 207 ? -20.333 -44.225 -17.193 1.000 125.883 0 207 SER LLL OG  1 ? 
ATOM   3086 N N   . PRO B 2 208 ? -16.651 -43.235 -16.497 1.000 96.638  0 208 PRO LLL N   1 ? 
ATOM   3087 C CA  . PRO B 2 208 ? -15.734 -42.703 -17.502 1.000 96.845  0 208 PRO LLL CA  1 ? 
ATOM   3088 C C   . PRO B 2 208 ? -16.344 -42.661 -18.910 1.000 94.284  0 208 PRO LLL C   1 ? 
ATOM   3089 O O   . PRO B 2 208 ? -16.973 -43.622 -19.323 1.000 85.578  0 208 PRO LLL O   1 ? 
ATOM   3090 C CB  . PRO B 2 208 ? -14.548 -43.671 -17.438 1.000 99.857  0 208 PRO LLL CB  1 ? 
ATOM   3091 C CG  . PRO B 2 208 ? -14.539 -44.122 -15.996 1.000 103.415 0 208 PRO LLL CG  1 ? 
ATOM   3092 C CD  . PRO B 2 208 ? -16.001 -44.211 -15.613 1.000 98.894  0 208 PRO LLL CD  1 ? 
ATOM   3093 N N   . VAL B 2 209 ? -16.173 -41.525 -19.588 1.000 95.390  0 209 VAL LLL N   1 ? 
ATOM   3094 C CA  . VAL B 2 209 ? -16.649 -41.283 -20.981 1.000 98.784  0 209 VAL LLL CA  1 ? 
ATOM   3095 C C   . VAL B 2 209 ? -15.479 -41.512 -21.945 1.000 104.180 0 209 VAL LLL C   1 ? 
ATOM   3096 O O   . VAL B 2 209 ? -14.369 -41.015 -21.661 1.000 96.287  0 209 VAL LLL O   1 ? 
ATOM   3097 C CB  . VAL B 2 209 ? -17.236 -39.868 -21.138 1.000 96.710  0 209 VAL LLL CB  1 ? 
ATOM   3098 C CG1 . VAL B 2 209 ? -17.464 -39.510 -22.599 1.000 95.801  0 209 VAL LLL CG1 1 ? 
ATOM   3099 C CG2 . VAL B 2 209 ? -18.518 -39.713 -20.335 1.000 100.427 0 209 VAL LLL CG2 1 ? 
ATOM   3100 N N   . THR B 2 210 ? -15.726 -42.229 -23.045 1.000 103.931 0 210 THR LLL N   1 ? 
ATOM   3101 C CA  . THR B 2 210 ? -14.704 -42.554 -24.072 1.000 100.782 0 210 THR LLL CA  1 ? 
ATOM   3102 C C   . THR B 2 210 ? -15.180 -42.020 -25.423 1.000 98.132  0 210 THR LLL C   1 ? 
ATOM   3103 O O   . THR B 2 210 ? -16.018 -42.670 -26.063 1.000 98.174  0 210 THR LLL O   1 ? 
ATOM   3104 C CB  . THR B 2 210 ? -14.383 -44.056 -24.106 1.000 98.225  0 210 THR LLL CB  1 ? 
ATOM   3105 O OG1 . THR B 2 210 ? -14.135 -44.509 -22.776 1.000 101.582 0 210 THR LLL OG1 1 ? 
ATOM   3106 C CG2 . THR B 2 210 ? -13.166 -44.377 -24.944 1.000 99.503  0 210 THR LLL CG2 1 ? 
ATOM   3107 N N   . LYS B 2 211 ? -14.638 -40.885 -25.853 1.000 101.526 0 211 LYS LLL N   1 ? 
ATOM   3108 C CA  . LYS B 2 211 ? -14.863 -40.365 -27.229 1.000 108.361 0 211 LYS LLL CA  1 ? 
ATOM   3109 C C   . LYS B 2 211 ? -13.908 -41.111 -28.167 1.000 110.375 0 211 LYS LLL C   1 ? 
ATOM   3110 O O   . LYS B 2 211 ? -12.707 -41.183 -27.852 1.000 108.063 0 211 LYS LLL O   1 ? 
ATOM   3111 C CB  . LYS B 2 211 ? -14.649 -38.849 -27.293 1.000 113.030 0 211 LYS LLL CB  1 ? 
ATOM   3112 C CG  . LYS B 2 211 ? -15.411 -38.032 -26.258 1.000 111.163 0 211 LYS LLL CG  1 ? 
ATOM   3113 C CD  . LYS B 2 211 ? -16.905 -38.125 -26.346 1.000 104.855 0 211 LYS LLL CD  1 ? 
ATOM   3114 C CE  . LYS B 2 211 ? -17.446 -37.456 -27.584 1.000 104.998 0 211 LYS LLL CE  1 ? 
ATOM   3115 N NZ  . LYS B 2 211 ? -18.918 -37.330 -27.504 1.000 101.822 0 211 LYS LLL NZ  1 ? 
ATOM   3116 N N   . SER B 2 212 ? -14.420 -41.673 -29.263 1.000 121.765 0 212 SER LLL N   1 ? 
ATOM   3117 C CA  . SER B 2 212 ? -13.621 -42.449 -30.252 1.000 120.913 0 212 SER LLL CA  1 ? 
ATOM   3118 C C   . SER B 2 212 ? -14.075 -42.138 -31.684 1.000 117.695 0 212 SER LLL C   1 ? 
ATOM   3119 O O   . SER B 2 212 ? -15.222 -41.703 -31.859 1.000 116.867 0 212 SER LLL O   1 ? 
ATOM   3120 C CB  . SER B 2 212 ? -13.682 -43.932 -29.950 1.000 118.346 0 212 SER LLL CB  1 ? 
ATOM   3121 O OG  . SER B 2 212 ? -14.993 -44.446 -30.103 1.000 120.609 0 212 SER LLL OG  1 ? 
ATOM   3122 N N   . PHE B 2 213 ? -13.191 -42.341 -32.666 1.000 122.577 0 213 PHE LLL N   1 ? 
ATOM   3123 C CA  . PHE B 2 213 ? -13.488 -42.242 -34.123 1.000 121.458 0 213 PHE LLL CA  1 ? 
ATOM   3124 C C   . PHE B 2 213 ? -12.757 -43.376 -34.853 1.000 127.330 0 213 PHE LLL C   1 ? 
ATOM   3125 O O   . PHE B 2 213 ? -11.668 -43.777 -34.395 1.000 132.013 0 213 PHE LLL O   1 ? 
ATOM   3126 C CB  . PHE B 2 213 ? -13.132 -40.851 -34.665 1.000 119.110 0 213 PHE LLL CB  1 ? 
ATOM   3127 C CG  . PHE B 2 213 ? -11.656 -40.547 -34.764 1.000 120.338 0 213 PHE LLL CG  1 ? 
ATOM   3128 C CD1 . PHE B 2 213 ? -10.955 -40.864 -35.913 1.000 124.233 0 213 PHE LLL CD1 1 ? 
ATOM   3129 C CD2 . PHE B 2 213 ? -10.968 -39.934 -33.725 1.000 125.584 0 213 PHE LLL CD2 1 ? 
ATOM   3130 C CE1 . PHE B 2 213 ? -9.598  -40.598 -36.016 1.000 129.029 0 213 PHE LLL CE1 1 ? 
ATOM   3131 C CE2 . PHE B 2 213 ? -9.611  -39.666 -33.831 1.000 122.422 0 213 PHE LLL CE2 1 ? 
ATOM   3132 C CZ  . PHE B 2 213 ? -8.927  -40.002 -34.974 1.000 126.107 0 213 PHE LLL CZ  1 ? 
ATOM   3133 N N   . ASN B 2 214 ? -13.351 -43.874 -35.945 1.000 135.163 0 214 ASN LLL N   1 ? 
ATOM   3134 C CA  . ASN B 2 214 ? -12.818 -44.974 -36.799 1.000 136.070 0 214 ASN LLL CA  1 ? 
ATOM   3135 C C   . ASN B 2 214 ? -12.132 -44.355 -38.030 1.000 141.884 0 214 ASN LLL C   1 ? 
ATOM   3136 O O   . ASN B 2 214 ? -11.798 -43.157 -37.977 1.000 154.826 0 214 ASN LLL O   1 ? 
ATOM   3137 C CB  . ASN B 2 214 ? -13.926 -45.969 -37.168 1.000 121.526 0 214 ASN LLL CB  1 ? 
ATOM   3138 N N   . ARG B 2 215 ? -11.919 -45.133 -39.099 1.000 145.812 0 215 ARG LLL N   1 ? 
ATOM   3139 C CA  . ARG B 2 215 ? -11.254 -44.684 -40.357 1.000 131.113 0 215 ARG LLL CA  1 ? 
ATOM   3140 C C   . ARG B 2 215 ? -9.934  -43.982 -40.009 1.000 128.756 0 215 ARG LLL C   1 ? 
ATOM   3141 O O   . ARG B 2 215 ? -9.779  -42.803 -40.381 1.000 138.971 0 215 ARG LLL O   1 ? 
ATOM   3142 C CB  . ARG B 2 215 ? -12.165 -43.749 -41.161 1.000 125.765 0 215 ARG LLL CB  1 ? 
ATOM   3143 C CG  . ARG B 2 215 ? -13.398 -44.421 -41.749 1.000 128.521 0 215 ARG LLL CG  1 ? 
ATOM   3144 C CD  . ARG B 2 215 ? -14.448 -43.419 -42.209 1.000 127.682 0 215 ARG LLL CD  1 ? 
ATOM   3145 N NE  . ARG B 2 215 ? -15.450 -43.117 -41.191 1.000 123.457 0 215 ARG LLL NE  1 ? 
ATOM   3146 C CZ  . ARG B 2 215 ? -16.430 -42.222 -41.319 1.000 115.036 0 215 ARG LLL CZ  1 ? 
ATOM   3147 N NH1 . ARG B 2 215 ? -17.283 -42.038 -40.325 1.000 105.716 0 215 ARG LLL NH1 1 ? 
ATOM   3148 N NH2 . ARG B 2 215 ? -16.556 -41.513 -42.428 1.000 117.376 0 215 ARG LLL NH2 1 ? 
ATOM   3149 N N   . GLY B 2 216 ? -9.036  -44.676 -39.302 1.000 120.479 0 216 GLY LLL N   1 ? 
ATOM   3150 C CA  . GLY B 2 216 ? -7.684  -44.190 -38.962 1.000 115.809 0 216 GLY LLL CA  1 ? 
ATOM   3151 C C   . GLY B 2 216 ? -6.695  -44.450 -40.088 1.000 118.716 0 216 GLY LLL C   1 ? 
ATOM   3152 O O   . GLY B 2 216 ? -5.899  -45.388 -40.037 1.000 126.241 0 216 GLY LLL O   1 ? 
HETATM 3153 C C1  . EDO C 3 .   ? -52.693 -9.441  12.959  1.000 74.475  0 301 EDO LLL C1  1 ? 
HETATM 3154 O O1  . EDO C 3 .   ? -51.779 -10.229 13.685  1.000 72.508  0 301 EDO LLL O1  1 ? 
HETATM 3155 C C2  . EDO C 3 .   ? -52.664 -8.011  13.358  1.000 74.864  0 301 EDO LLL C2  1 ? 
HETATM 3156 O O2  . EDO C 3 .   ? -51.385 -7.425  13.256  1.000 67.662  0 301 EDO LLL O2  1 ? 
HETATM 3157 O O   . HOH D 4 .   ? -7.279  -16.037 24.766  1.000 62.424  0 301 HOH HHH O   1 ? 
HETATM 3158 O O   . HOH D 4 .   ? -2.334  -12.482 32.195  1.000 64.676  0 302 HOH HHH O   1 ? 
HETATM 3159 O O   . HOH D 4 .   ? -17.957 -14.307 26.877  1.000 55.913  0 303 HOH HHH O   1 ? 
HETATM 3160 O O   . HOH D 4 .   ? -45.004 -7.116  22.253  1.000 62.477  0 304 HOH HHH O   1 ? 
HETATM 3161 O O   . HOH D 4 .   ? -34.543 -4.331  27.191  1.000 72.394  0 305 HOH HHH O   1 ? 
HETATM 3162 O O   . HOH D 4 .   ? -22.780 -21.279 24.410  1.000 48.115  0 306 HOH HHH O   1 ? 
HETATM 3163 O O   . HOH D 4 .   ? -32.318 -20.946 28.963  1.000 60.506  0 307 HOH HHH O   1 ? 
HETATM 3164 O O   . HOH D 4 .   ? 4.698   -13.617 39.320  1.000 63.184  0 308 HOH HHH O   1 ? 
HETATM 3165 O O   . HOH D 4 .   ? -15.033 -17.798 40.409  1.000 66.598  0 309 HOH HHH O   1 ? 
HETATM 3166 O O   . HOH D 4 .   ? -39.221 -14.066 39.403  1.000 59.939  0 310 HOH HHH O   1 ? 
HETATM 3167 O O   . HOH D 4 .   ? -21.687 -12.694 19.118  1.000 47.463  0 311 HOH HHH O   1 ? 
HETATM 3168 O O   . HOH E 4 .   ? -42.594 -19.552 2.905   1.000 62.584  0 401 HOH LLL O   1 ? 
HETATM 3169 O O   . HOH E 4 .   ? -3.037  -41.952 -22.929 1.000 53.023  0 402 HOH LLL O   1 ? 
HETATM 3170 O O   . HOH E 4 .   ? -58.729 -6.139  16.968  1.000 59.866  0 403 HOH LLL O   1 ? 
HETATM 3171 O O   . HOH E 4 .   ? -42.500 -28.358 8.553   1.000 42.736  0 404 HOH LLL O   1 ? 
HETATM 3172 O O   . HOH E 4 .   ? -44.175 -18.249 5.132   1.000 54.271  0 405 HOH LLL O   1 ? 
HETATM 3173 O O   . HOH E 4 .   ? -46.387 -26.204 24.245  1.000 71.380  0 406 HOH LLL O   1 ? 
HETATM 3174 O O   . HOH E 4 .   ? -34.813 -27.876 13.161  1.000 51.166  0 407 HOH LLL O   1 ? 
HETATM 3175 O O   . HOH E 4 .   ? -38.522 -17.792 -4.608  1.000 44.911  0 408 HOH LLL O   1 ? 
HETATM 3176 O O   . HOH E 4 .   ? -25.144 -21.492 9.368   1.000 49.051  0 409 HOH LLL O   1 ? 
HETATM 3177 O O   . HOH E 4 .   ? -34.608 -28.734 -6.077  1.000 87.433  0 410 HOH LLL O   1 ? 
HETATM 3178 O O   . HOH E 4 .   ? -33.806 -22.214 -9.869  1.000 63.401  0 411 HOH LLL O   1 ? 
HETATM 3179 O O   . HOH E 4 .   ? -42.339 -5.143  6.695   1.000 107.712 0 412 HOH LLL O   1 ? 
HETATM 3180 O O   . HOH E 4 .   ? -42.755 -5.594  2.657   1.000 40.159  0 413 HOH LLL O   1 ? 
HETATM 3181 O O   . HOH E 4 .   ? -38.159 -19.885 20.944  1.000 42.650  0 414 HOH LLL O   1 ? 
HETATM 3182 O O   . HOH E 4 .   ? -28.783 -13.499 1.065   1.000 53.563  0 415 HOH LLL O   1 ? 
HETATM 3183 O O   . HOH E 4 .   ? -6.136  -28.207 -8.430  1.000 62.544  0 416 HOH LLL O   1 ? 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU HHH . n 
A 1 2   VAL 2   2   2   VAL VAL HHH . n 
A 1 3   LEU 3   3   3   LEU LEU HHH . n 
A 1 4   LEU 4   4   4   LEU LEU HHH . n 
A 1 5   LEU 5   5   5   LEU LEU HHH . n 
A 1 6   GLN 6   6   6   GLN GLN HHH . n 
A 1 7   SER 7   7   7   SER SER HHH . n 
A 1 8   GLY 8   8   8   GLY GLY HHH . n 
A 1 9   PRO 9   9   9   PRO PRO HHH . n 
A 1 10  GLU 10  10  10  GLU GLU HHH . n 
A 1 11  LEU 11  11  11  LEU LEU HHH . n 
A 1 12  VAL 12  12  12  VAL VAL HHH . n 
A 1 13  LYS 13  13  13  LYS LYS HHH . n 
A 1 14  PRO 14  14  14  PRO PRO HHH . n 
A 1 15  GLY 15  15  15  GLY GLY HHH . n 
A 1 16  THR 16  16  16  THR THR HHH . n 
A 1 17  SER 17  17  17  SER SER HHH . n 
A 1 18  VAL 18  18  18  VAL VAL HHH . n 
A 1 19  LYS 19  19  19  LYS LYS HHH . n 
A 1 20  ILE 20  20  20  ILE ILE HHH . n 
A 1 21  PRO 21  21  21  PRO PRO HHH . n 
A 1 22  CYS 22  22  22  CYS CYS HHH . n 
A 1 23  LYS 23  23  23  LYS LYS HHH . n 
A 1 24  ALA 24  24  24  ALA ALA HHH . n 
A 1 25  SER 25  25  25  SER SER HHH . n 
A 1 26  GLY 26  26  26  GLY GLY HHH . n 
A 1 27  TYR 27  27  27  TYR TYR HHH . n 
A 1 28  THR 28  28  28  THR THR HHH . n 
A 1 29  PHE 29  29  29  PHE PHE HHH . n 
A 1 30  THR 30  30  30  THR THR HHH . n 
A 1 31  ASP 31  31  31  ASP ASP HHH . n 
A 1 32  TYR 32  32  32  TYR TYR HHH . n 
A 1 33  ASN 33  33  33  ASN ASN HHH . n 
A 1 34  VAL 34  34  34  VAL VAL HHH . n 
A 1 35  ASP 35  35  35  ASP ASP HHH . n 
A 1 36  TRP 36  36  36  TRP TRP HHH . n 
A 1 37  VAL 37  37  37  VAL VAL HHH . n 
A 1 38  LYS 38  38  38  LYS LYS HHH . n 
A 1 39  GLN 39  39  39  GLN GLN HHH . n 
A 1 40  ARG 40  40  40  ARG ARG HHH . n 
A 1 41  HIS 41  41  41  HIS HIS HHH . n 
A 1 42  GLY 42  42  42  GLY GLY HHH . n 
A 1 43  LYS 43  43  43  LYS LYS HHH . n 
A 1 44  GLY 44  44  44  GLY GLY HHH . n 
A 1 45  LEU 45  45  45  LEU LEU HHH . n 
A 1 46  GLU 46  46  46  GLU GLU HHH . n 
A 1 47  TRP 47  47  47  TRP TRP HHH . n 
A 1 48  ILE 48  48  48  ILE ILE HHH . n 
A 1 49  GLY 49  49  49  GLY GLY HHH . n 
A 1 50  ASP 50  50  50  ASP ASP HHH . n 
A 1 51  ILE 51  51  51  ILE ILE HHH . n 
A 1 52  ASN 52  52  52  ASN ASN HHH . n 
A 1 53  PRO 53  53  53  PRO PRO HHH . n 
A 1 54  ASN 54  54  54  ASN ASN HHH . n 
A 1 55  ASN 55  55  55  ASN ASN HHH . n 
A 1 56  GLY 56  56  56  GLY GLY HHH . n 
A 1 57  GLY 57  57  57  GLY GLY HHH . n 
A 1 58  THR 58  58  58  THR THR HHH . n 
A 1 59  ILE 59  59  59  ILE ILE HHH . n 
A 1 60  TYR 60  60  60  TYR TYR HHH . n 
A 1 61  SER 61  61  61  SER SER HHH . n 
A 1 62  GLN 62  62  62  GLN GLN HHH . n 
A 1 63  LYS 63  63  63  LYS LYS HHH . n 
A 1 64  PHE 64  64  64  PHE PHE HHH . n 
A 1 65  LYS 65  65  65  LYS LYS HHH . n 
A 1 66  GLY 66  66  66  GLY GLY HHH . n 
A 1 67  LYS 67  67  67  LYS LYS HHH . n 
A 1 68  ALA 68  68  68  ALA ALA HHH . n 
A 1 69  THR 69  69  69  THR THR HHH . n 
A 1 70  LEU 70  70  70  LEU LEU HHH . n 
A 1 71  THR 71  71  71  THR THR HHH . n 
A 1 72  VAL 72  72  72  VAL VAL HHH . n 
A 1 73  ASP 73  73  73  ASP ASP HHH . n 
A 1 74  LYS 74  74  74  LYS LYS HHH . n 
A 1 75  SER 75  75  75  SER SER HHH . n 
A 1 76  SER 76  76  76  SER SER HHH . n 
A 1 77  SER 77  77  77  SER SER HHH . n 
A 1 78  THR 78  78  78  THR THR HHH . n 
A 1 79  ALA 79  79  79  ALA ALA HHH . n 
A 1 80  PHE 80  80  80  PHE PHE HHH . n 
A 1 81  MET 81  81  81  MET MET HHH . n 
A 1 82  GLU 82  82  82  GLU GLU HHH . n 
A 1 83  LEU 83  83  83  LEU LEU HHH . n 
A 1 84  ARG 84  84  84  ARG ARG HHH . n 
A 1 85  SER 85  85  85  SER SER HHH . n 
A 1 86  LEU 86  86  86  LEU LEU HHH . n 
A 1 87  THR 87  87  87  THR THR HHH . n 
A 1 88  SER 88  88  88  SER SER HHH . n 
A 1 89  GLU 89  89  89  GLU GLU HHH . n 
A 1 90  ASP 90  90  90  ASP ASP HHH . n 
A 1 91  THR 91  91  91  THR THR HHH . n 
A 1 92  ALA 92  92  92  ALA ALA HHH . n 
A 1 93  VAL 93  93  93  VAL VAL HHH . n 
A 1 94  TYR 94  94  94  TYR TYR HHH . n 
A 1 95  PHE 95  95  95  PHE PHE HHH . n 
A 1 96  CYS 96  96  96  CYS CYS HHH . n 
A 1 97  ALA 97  97  97  ALA ALA HHH . n 
A 1 98  ARG 98  98  98  ARG ARG HHH . n 
A 1 99  ASN 99  99  99  ASN ASN HHH . n 
A 1 100 TYR 100 100 100 TYR TYR HHH . n 
A 1 101 ARG 101 101 101 ARG ARG HHH . n 
A 1 102 TRP 102 102 102 TRP TRP HHH . n 
A 1 103 PHE 103 103 103 PHE PHE HHH . n 
A 1 104 GLY 104 104 104 GLY GLY HHH . n 
A 1 105 ALA 105 105 105 ALA ALA HHH . n 
A 1 106 MET 106 106 106 MET MET HHH . n 
A 1 107 ASP 107 107 107 ASP ASP HHH . n 
A 1 108 HIS 108 108 108 HIS HIS HHH . n 
A 1 109 TRP 109 109 109 TRP TRP HHH . n 
A 1 110 GLY 110 110 110 GLY GLY HHH . n 
A 1 111 GLN 111 111 111 GLN GLN HHH . n 
A 1 112 GLY 112 112 112 GLY GLY HHH . n 
A 1 113 THR 113 113 113 THR THR HHH . n 
A 1 114 SER 114 114 114 SER SER HHH . n 
A 1 115 VAL 115 115 115 VAL VAL HHH . n 
A 1 116 THR 116 116 116 THR THR HHH . n 
A 1 117 VAL 117 117 117 VAL VAL HHH . n 
A 1 118 SER 118 118 118 SER SER HHH . n 
A 1 119 SER 119 119 119 SER SER HHH . n 
A 1 120 THR 120 120 120 THR THR HHH . n 
A 1 121 LYS 121 121 121 LYS LYS HHH . n 
A 1 122 GLY 122 122 122 GLY GLY HHH . n 
A 1 123 PRO 123 123 123 PRO PRO HHH . n 
A 1 124 SER 124 124 124 SER SER HHH . n 
A 1 125 VAL 125 125 125 VAL VAL HHH . n 
A 1 126 PHE 126 126 126 PHE PHE HHH . n 
A 1 127 PRO 127 127 127 PRO PRO HHH . n 
A 1 128 LEU 128 128 128 LEU LEU HHH . n 
A 1 129 ALA 129 129 129 ALA ALA HHH . n 
A 1 130 PRO 130 130 130 PRO PRO HHH . n 
A 1 131 SER 131 131 131 SER SER HHH . n 
A 1 132 SER 132 132 132 SER SER HHH . n 
A 1 133 LYS 133 133 ?   ?   ?   HHH . n 
A 1 134 SER 134 134 ?   ?   ?   HHH . n 
A 1 135 THR 135 135 ?   ?   ?   HHH . n 
A 1 136 SER 136 136 ?   ?   ?   HHH . n 
A 1 137 GLY 137 137 ?   ?   ?   HHH . n 
A 1 138 GLY 138 138 ?   ?   ?   HHH . n 
A 1 139 THR 139 139 139 THR THR HHH . n 
A 1 140 ALA 140 140 140 ALA ALA HHH . n 
A 1 141 ALA 141 141 141 ALA ALA HHH . n 
A 1 142 LEU 142 142 142 LEU LEU HHH . n 
A 1 143 GLY 143 143 143 GLY GLY HHH . n 
A 1 144 CYS 144 144 144 CYS CYS HHH . n 
A 1 145 LEU 145 145 145 LEU LEU HHH . n 
A 1 146 VAL 146 146 146 VAL VAL HHH . n 
A 1 147 LYS 147 147 147 LYS LYS HHH . n 
A 1 148 ASP 148 148 148 ASP ASP HHH . n 
A 1 149 TYR 149 149 149 TYR TYR HHH . n 
A 1 150 PHE 150 150 150 PHE PHE HHH . n 
A 1 151 PRO 151 151 151 PRO PRO HHH . n 
A 1 152 GLU 152 152 152 GLU GLU HHH . n 
A 1 153 PRO 153 153 153 PRO PRO HHH . n 
A 1 154 VAL 154 154 154 VAL VAL HHH . n 
A 1 155 THR 155 155 155 THR THR HHH . n 
A 1 156 VAL 156 156 156 VAL VAL HHH . n 
A 1 157 SER 157 157 157 SER SER HHH . n 
A 1 158 TRP 158 158 158 TRP TRP HHH . n 
A 1 159 ASN 159 159 159 ASN ASN HHH . n 
A 1 160 SER 160 160 160 SER SER HHH . n 
A 1 161 GLY 161 161 161 GLY GLY HHH . n 
A 1 162 ALA 162 162 162 ALA ALA HHH . n 
A 1 163 LEU 163 163 163 LEU LEU HHH . n 
A 1 164 THR 164 164 164 THR THR HHH . n 
A 1 165 SER 165 165 165 SER SER HHH . n 
A 1 166 GLY 166 166 166 GLY GLY HHH . n 
A 1 167 VAL 167 167 167 VAL VAL HHH . n 
A 1 168 HIS 168 168 168 HIS HIS HHH . n 
A 1 169 THR 169 169 169 THR THR HHH . n 
A 1 170 PHE 170 170 170 PHE PHE HHH . n 
A 1 171 PRO 171 171 171 PRO PRO HHH . n 
A 1 172 ALA 172 172 172 ALA ALA HHH . n 
A 1 173 VAL 173 173 173 VAL VAL HHH . n 
A 1 174 LEU 174 174 174 LEU LEU HHH . n 
A 1 175 GLN 175 175 175 GLN GLN HHH . n 
A 1 176 SER 176 176 176 SER SER HHH . n 
A 1 177 SER 177 177 177 SER SER HHH . n 
A 1 178 GLY 178 178 178 GLY GLY HHH . n 
A 1 179 LEU 179 179 179 LEU LEU HHH . n 
A 1 180 TYR 180 180 180 TYR TYR HHH . n 
A 1 181 SER 181 181 181 SER SER HHH . n 
A 1 182 LEU 182 182 182 LEU LEU HHH . n 
A 1 183 SER 183 183 183 SER SER HHH . n 
A 1 184 SER 184 184 184 SER SER HHH . n 
A 1 185 VAL 185 185 185 VAL VAL HHH . n 
A 1 186 VAL 186 186 186 VAL VAL HHH . n 
A 1 187 THR 187 187 187 THR THR HHH . n 
A 1 188 VAL 188 188 188 VAL VAL HHH . n 
A 1 189 PRO 189 189 189 PRO PRO HHH . n 
A 1 190 SER 190 190 190 SER SER HHH . n 
A 1 191 SER 191 191 191 SER SER HHH . n 
A 1 192 SER 192 192 192 SER SER HHH . n 
A 1 193 LEU 193 193 193 LEU LEU HHH . n 
A 1 194 GLY 194 194 194 GLY GLY HHH . n 
A 1 195 THR 195 195 195 THR THR HHH . n 
A 1 196 GLN 196 196 196 GLN GLN HHH . n 
A 1 197 THR 197 197 197 THR THR HHH . n 
A 1 198 TYR 198 198 198 TYR TYR HHH . n 
A 1 199 ILE 199 199 199 ILE ILE HHH . n 
A 1 200 CYS 200 200 200 CYS CYS HHH . n 
A 1 201 ASN 201 201 201 ASN ASN HHH . n 
A 1 202 VAL 202 202 202 VAL VAL HHH . n 
A 1 203 ASN 203 203 203 ASN ASN HHH . n 
A 1 204 HIS 204 204 204 HIS HIS HHH . n 
A 1 205 LYS 205 205 205 LYS LYS HHH . n 
A 1 206 PRO 206 206 206 PRO PRO HHH . n 
A 1 207 SER 207 207 207 SER SER HHH . n 
A 1 208 ASN 208 208 208 ASN ASN HHH . n 
A 1 209 THR 209 209 209 THR THR HHH . n 
A 1 210 LYS 210 210 210 LYS LYS HHH . n 
A 1 211 VAL 211 211 211 VAL VAL HHH . n 
A 1 212 ASP 212 212 212 ASP ASP HHH . n 
A 1 213 LYS 213 213 213 LYS LYS HHH . n 
A 1 214 ARG 214 214 214 ARG ARG HHH . n 
A 1 215 VAL 215 215 215 VAL VAL HHH . n 
A 1 216 GLU 216 216 216 GLU GLU HHH . n 
A 1 217 PRO 217 217 217 PRO PRO HHH . n 
A 1 218 LYS 218 218 218 LYS LYS HHH . n 
A 1 219 SER 219 219 219 SER SER HHH . n 
A 1 220 CYS 220 220 ?   ?   ?   HHH . n 
A 1 221 ASP 221 221 ?   ?   ?   HHH . n 
A 1 222 LYS 222 222 ?   ?   ?   HHH . n 
A 1 223 THR 223 223 ?   ?   ?   HHH . n 
B 2 1   ASP 1   1   1   ASP ASP LLL . n 
B 2 2   ILE 2   2   2   ILE ILE LLL . n 
B 2 3   VAL 3   3   3   VAL VAL LLL . n 
B 2 4   LEU 4   4   4   LEU LEU LLL . n 
B 2 5   THR 5   5   5   THR THR LLL . n 
B 2 6   GLN 6   6   6   GLN GLN LLL . n 
B 2 7   SER 7   7   7   SER SER LLL . n 
B 2 8   PRO 8   8   8   PRO PRO LLL . n 
B 2 9   ALA 9   9   9   ALA ALA LLL . n 
B 2 10  SER 10  10  10  SER SER LLL . n 
B 2 11  LEU 11  11  11  LEU LEU LLL . n 
B 2 12  ALA 12  12  12  ALA ALA LLL . n 
B 2 13  VAL 13  13  13  VAL VAL LLL . n 
B 2 14  SER 14  14  14  SER SER LLL . n 
B 2 15  PRO 15  15  15  PRO PRO LLL . n 
B 2 16  GLY 16  16  16  GLY GLY LLL . n 
B 2 17  GLN 17  17  17  GLN GLN LLL . n 
B 2 18  ARG 18  18  18  ARG ARG LLL . n 
B 2 19  ALA 19  19  19  ALA ALA LLL . n 
B 2 20  THR 20  20  20  THR THR LLL . n 
B 2 21  ILE 21  21  21  ILE ILE LLL . n 
B 2 22  SER 22  22  22  SER SER LLL . n 
B 2 23  CYS 23  23  23  CYS CYS LLL . n 
B 2 24  LYS 24  24  24  LYS LYS LLL . n 
B 2 25  ALA 25  25  25  ALA ALA LLL . n 
B 2 26  SER 26  26  26  SER SER LLL . n 
B 2 27  GLN 27  27  27  GLN GLN LLL . n 
B 2 28  SER 28  28  28  SER SER LLL . n 
B 2 29  LEU 29  29  29  LEU LEU LLL . n 
B 2 30  ASP 30  30  30  ASP ASP LLL . n 
B 2 31  TYR 31  31  31  TYR TYR LLL . n 
B 2 32  GLU 32  32  32  GLU GLU LLL . n 
B 2 33  GLY 33  33  33  GLY GLY LLL . n 
B 2 34  ASP 34  34  34  ASP ASP LLL . n 
B 2 35  SER 35  35  35  SER SER LLL . n 
B 2 36  ASP 36  36  36  ASP ASP LLL . n 
B 2 37  MET 37  37  37  MET MET LLL . n 
B 2 38  ASN 38  38  38  ASN ASN LLL . n 
B 2 39  TRP 39  39  39  TRP TRP LLL . n 
B 2 40  TYR 40  40  40  TYR TYR LLL . n 
B 2 41  GLN 41  41  41  GLN GLN LLL . n 
B 2 42  GLN 42  42  42  GLN GLN LLL . n 
B 2 43  LYS 43  43  43  LYS LYS LLL . n 
B 2 44  PRO 44  44  44  PRO PRO LLL . n 
B 2 45  GLY 45  45  45  GLY GLY LLL . n 
B 2 46  GLN 46  46  46  GLN GLN LLL . n 
B 2 47  PRO 47  47  47  PRO PRO LLL . n 
B 2 48  PRO 48  48  48  PRO PRO LLL . n 
B 2 49  ARG 49  49  49  ARG ARG LLL . n 
B 2 50  LEU 50  50  50  LEU LEU LLL . n 
B 2 51  LEU 51  51  51  LEU LEU LLL . n 
B 2 52  ILE 52  52  52  ILE ILE LLL . n 
B 2 53  SER 53  53  53  SER SER LLL . n 
B 2 54  GLY 54  54  54  GLY GLY LLL . n 
B 2 55  ALA 55  55  55  ALA ALA LLL . n 
B 2 56  SER 56  56  56  SER SER LLL . n 
B 2 57  ASN 57  57  57  ASN ASN LLL . n 
B 2 58  LEU 58  58  58  LEU LEU LLL . n 
B 2 59  GLU 59  59  59  GLU GLU LLL . n 
B 2 60  SER 60  60  60  SER SER LLL . n 
B 2 61  GLY 61  61  61  GLY GLY LLL . n 
B 2 62  ILE 62  62  62  ILE ILE LLL . n 
B 2 63  PRO 63  63  63  PRO PRO LLL . n 
B 2 64  ALA 64  64  64  ALA ALA LLL . n 
B 2 65  ARG 65  65  65  ARG ARG LLL . n 
B 2 66  PHE 66  66  66  PHE PHE LLL . n 
B 2 67  SER 67  67  67  SER SER LLL . n 
B 2 68  GLY 68  68  68  GLY GLY LLL . n 
B 2 69  SER 69  69  69  SER SER LLL . n 
B 2 70  GLY 70  70  70  GLY GLY LLL . n 
B 2 71  SER 71  71  71  SER SER LLL . n 
B 2 72  GLY 72  72  72  GLY GLY LLL . n 
B 2 73  THR 73  73  73  THR THR LLL . n 
B 2 74  ASP 74  74  74  ASP ASP LLL . n 
B 2 75  PHE 75  75  75  PHE PHE LLL . n 
B 2 76  THR 76  76  76  THR THR LLL . n 
B 2 77  VAL 77  77  77  VAL VAL LLL . n 
B 2 78  ASN 78  78  78  ASN ASN LLL . n 
B 2 79  ILE 79  79  79  ILE ILE LLL . n 
B 2 80  HIS 80  80  80  HIS HIS LLL . n 
B 2 81  PRO 81  81  81  PRO PRO LLL . n 
B 2 82  VAL 82  82  82  VAL VAL LLL . n 
B 2 83  GLU 83  83  83  GLU GLU LLL . n 
B 2 84  GLU 84  84  84  GLU GLU LLL . n 
B 2 85  GLU 85  85  85  GLU GLU LLL . n 
B 2 86  ASP 86  86  86  ASP ASP LLL . n 
B 2 87  ALA 87  87  87  ALA ALA LLL . n 
B 2 88  ALA 88  88  88  ALA ALA LLL . n 
B 2 89  THR 89  89  89  THR THR LLL . n 
B 2 90  TYR 90  90  90  TYR TYR LLL . n 
B 2 91  TYR 91  91  91  TYR TYR LLL . n 
B 2 92  CYS 92  92  92  CYS CYS LLL . n 
B 2 93  GLN 93  93  93  GLN GLN LLL . n 
B 2 94  GLN 94  94  94  GLN GLN LLL . n 
B 2 95  SER 95  95  95  SER SER LLL . n 
B 2 96  THR 96  96  96  THR THR LLL . n 
B 2 97  GLU 97  97  97  GLU GLU LLL . n 
B 2 98  ASP 98  98  98  ASP ASP LLL . n 
B 2 99  PRO 99  99  99  PRO PRO LLL . n 
B 2 100 ARG 100 100 100 ARG ARG LLL . n 
B 2 101 THR 101 101 101 THR THR LLL . n 
B 2 102 PHE 102 102 102 PHE PHE LLL . n 
B 2 103 GLY 103 103 103 GLY GLY LLL . n 
B 2 104 GLY 104 104 104 GLY GLY LLL . n 
B 2 105 GLY 105 105 105 GLY GLY LLL . n 
B 2 106 THR 106 106 106 THR THR LLL . n 
B 2 107 LYS 107 107 107 LYS LYS LLL . n 
B 2 108 LEU 108 108 108 LEU LEU LLL . n 
B 2 109 GLU 109 109 109 GLU GLU LLL . n 
B 2 110 ILE 110 110 110 ILE ILE LLL . n 
B 2 111 LYS 111 111 111 LYS LYS LLL . n 
B 2 112 ARG 112 112 112 ARG ARG LLL . n 
B 2 113 THR 113 113 113 THR THR LLL . n 
B 2 114 VAL 114 114 114 VAL VAL LLL . n 
B 2 115 ALA 115 115 115 ALA ALA LLL . n 
B 2 116 ALA 116 116 116 ALA ALA LLL . n 
B 2 117 PRO 117 117 117 PRO PRO LLL . n 
B 2 118 SER 118 118 118 SER SER LLL . n 
B 2 119 VAL 119 119 119 VAL VAL LLL . n 
B 2 120 PHE 120 120 120 PHE PHE LLL . n 
B 2 121 ILE 121 121 121 ILE ILE LLL . n 
B 2 122 PHE 122 122 122 PHE PHE LLL . n 
B 2 123 PRO 123 123 123 PRO PRO LLL . n 
B 2 124 PRO 124 124 124 PRO PRO LLL . n 
B 2 125 SER 125 125 125 SER SER LLL . n 
B 2 126 ASP 126 126 126 ASP ASP LLL . n 
B 2 127 GLU 127 127 127 GLU GLU LLL . n 
B 2 128 GLN 128 128 128 GLN GLN LLL . n 
B 2 129 LEU 129 129 129 LEU LEU LLL . n 
B 2 130 LYS 130 130 130 LYS LYS LLL . n 
B 2 131 SER 131 131 131 SER SER LLL . n 
B 2 132 GLY 132 132 132 GLY GLY LLL . n 
B 2 133 THR 133 133 133 THR THR LLL . n 
B 2 134 ALA 134 134 134 ALA ALA LLL . n 
B 2 135 SER 135 135 135 SER SER LLL . n 
B 2 136 VAL 136 136 136 VAL VAL LLL . n 
B 2 137 VAL 137 137 137 VAL VAL LLL . n 
B 2 138 CYS 138 138 138 CYS CYS LLL . n 
B 2 139 LEU 139 139 139 LEU LEU LLL . n 
B 2 140 LEU 140 140 140 LEU LEU LLL . n 
B 2 141 ASN 141 141 141 ASN ASN LLL . n 
B 2 142 ASN 142 142 142 ASN ASN LLL . n 
B 2 143 PHE 143 143 143 PHE PHE LLL . n 
B 2 144 TYR 144 144 144 TYR TYR LLL . n 
B 2 145 PRO 145 145 145 PRO PRO LLL . n 
B 2 146 ARG 146 146 146 ARG ARG LLL . n 
B 2 147 GLU 147 147 147 GLU GLU LLL . n 
B 2 148 ALA 148 148 148 ALA ALA LLL . n 
B 2 149 LYS 149 149 149 LYS LYS LLL . n 
B 2 150 TYR 150 150 150 TYR TYR LLL . n 
B 2 151 GLN 151 151 151 GLN GLN LLL . n 
B 2 152 TRP 152 152 152 TRP TRP LLL . n 
B 2 153 LYS 153 153 153 LYS LYS LLL . n 
B 2 154 VAL 154 154 154 VAL VAL LLL . n 
B 2 155 ASP 155 155 155 ASP ASP LLL . n 
B 2 156 ASN 156 156 156 ASN ASN LLL . n 
B 2 157 ALA 157 157 157 ALA ALA LLL . n 
B 2 158 LEU 158 158 158 LEU LEU LLL . n 
B 2 159 GLN 159 159 159 GLN GLN LLL . n 
B 2 160 SER 160 160 160 SER SER LLL . n 
B 2 161 GLY 161 161 161 GLY GLY LLL . n 
B 2 162 ASN 162 162 162 ASN ASN LLL . n 
B 2 163 SER 163 163 163 SER SER LLL . n 
B 2 164 GLN 164 164 164 GLN GLN LLL . n 
B 2 165 GLU 165 165 165 GLU GLU LLL . n 
B 2 166 SER 166 166 166 SER SER LLL . n 
B 2 167 VAL 167 167 167 VAL VAL LLL . n 
B 2 168 THR 168 168 168 THR THR LLL . n 
B 2 169 GLU 169 169 169 GLU GLU LLL . n 
B 2 170 GLN 170 170 170 GLN GLN LLL . n 
B 2 171 ASP 171 171 171 ASP ASP LLL . n 
B 2 172 SER 172 172 172 SER SER LLL . n 
B 2 173 LYS 173 173 173 LYS LYS LLL . n 
B 2 174 ASP 174 174 174 ASP ASP LLL . n 
B 2 175 SER 175 175 175 SER SER LLL . n 
B 2 176 THR 176 176 176 THR THR LLL . n 
B 2 177 TYR 177 177 177 TYR TYR LLL . n 
B 2 178 SER 178 178 178 SER SER LLL . n 
B 2 179 LEU 179 179 179 LEU LEU LLL . n 
B 2 180 SER 180 180 180 SER SER LLL . n 
B 2 181 SER 181 181 181 SER SER LLL . n 
B 2 182 THR 182 182 182 THR THR LLL . n 
B 2 183 LEU 183 183 183 LEU LEU LLL . n 
B 2 184 THR 184 184 184 THR THR LLL . n 
B 2 185 LEU 185 185 185 LEU LEU LLL . n 
B 2 186 SER 186 186 186 SER SER LLL . n 
B 2 187 LYS 187 187 187 LYS LYS LLL . n 
B 2 188 ALA 188 188 188 ALA ALA LLL . n 
B 2 189 ASP 189 189 189 ASP ASP LLL . n 
B 2 190 TYR 190 190 190 TYR TYR LLL . n 
B 2 191 GLU 191 191 191 GLU GLU LLL . n 
B 2 192 LYS 192 192 192 LYS LYS LLL . n 
B 2 193 HIS 193 193 193 HIS HIS LLL . n 
B 2 194 LYS 194 194 194 LYS LYS LLL . n 
B 2 195 VAL 195 195 195 VAL VAL LLL . n 
B 2 196 TYR 196 196 196 TYR TYR LLL . n 
B 2 197 ALA 197 197 197 ALA ALA LLL . n 
B 2 198 CYS 198 198 198 CYS CYS LLL . n 
B 2 199 GLU 199 199 199 GLU GLU LLL . n 
B 2 200 VAL 200 200 200 VAL VAL LLL . n 
B 2 201 THR 201 201 201 THR THR LLL . n 
B 2 202 HIS 202 202 202 HIS HIS LLL . n 
B 2 203 GLN 203 203 203 GLN GLN LLL . n 
B 2 204 GLY 204 204 204 GLY GLY LLL . n 
B 2 205 LEU 205 205 205 LEU LEU LLL . n 
B 2 206 SER 206 206 206 SER SER LLL . n 
B 2 207 SER 207 207 207 SER SER LLL . n 
B 2 208 PRO 208 208 208 PRO PRO LLL . n 
B 2 209 VAL 209 209 209 VAL VAL LLL . n 
B 2 210 THR 210 210 210 THR THR LLL . n 
B 2 211 LYS 211 211 211 LYS LYS LLL . n 
B 2 212 SER 212 212 212 SER SER LLL . n 
B 2 213 PHE 213 213 213 PHE PHE LLL . n 
B 2 214 ASN 214 214 214 ASN ASN LLL . n 
B 2 215 ARG 215 215 215 ARG ARG LLL . n 
B 2 216 GLY 216 216 216 GLY GLY LLL . n 
B 2 217 GLU 217 217 ?   ?   ?   LLL . n 
B 2 218 CYS 218 218 ?   ?   ?   LLL . n 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              rmariuzz@umd.edu 
_pdbx_contact_author.name_first         Roy 
_pdbx_contact_author.name_last          Mariuzza 
_pdbx_contact_author.name_mi            A 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0748-5875 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 EDO 1  301 301 EDO EDO LLL . 
D 4 HOH 1  301 26  HOH HOH HHH . 
D 4 HOH 2  302 27  HOH HOH HHH . 
D 4 HOH 3  303 4   HOH HOH HHH . 
D 4 HOH 4  304 1   HOH HOH HHH . 
D 4 HOH 5  305 22  HOH HOH HHH . 
D 4 HOH 6  306 2   HOH HOH HHH . 
D 4 HOH 7  307 3   HOH HOH HHH . 
D 4 HOH 8  308 23  HOH HOH HHH . 
D 4 HOH 9  309 21  HOH HOH HHH . 
D 4 HOH 10 310 7   HOH HOH HHH . 
D 4 HOH 11 311 9   HOH HOH HHH . 
E 4 HOH 1  401 25  HOH HOH LLL . 
E 4 HOH 2  402 20  HOH HOH LLL . 
E 4 HOH 3  403 15  HOH HOH LLL . 
E 4 HOH 4  404 13  HOH HOH LLL . 
E 4 HOH 5  405 24  HOH HOH LLL . 
E 4 HOH 6  406 12  HOH HOH LLL . 
E 4 HOH 7  407 11  HOH HOH LLL . 
E 4 HOH 8  408 17  HOH HOH LLL . 
E 4 HOH 9  409 5   HOH HOH LLL . 
E 4 HOH 10 410 16  HOH HOH LLL . 
E 4 HOH 11 411 18  HOH HOH LLL . 
E 4 HOH 12 412 14  HOH HOH LLL . 
E 4 HOH 13 413 10  HOH HOH LLL . 
E 4 HOH 14 414 19  HOH HOH LLL . 
E 4 HOH 15 415 8   HOH HOH LLL . 
E 4 HOH 16 416 6   HOH HOH LLL . 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6920  ? 
1 MORE         -35   ? 
1 'SSA (A^2)'  38430 ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000  0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 2_555 -x,y,-z -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2023-09-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0267 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .        4 
# 
_pdbx_entry_details.entry_id                 8FWH 
_pdbx_entry_details.has_ligand_of_interest   Y 
_pdbx_entry_details.compound_details         ? 
_pdbx_entry_details.source_details           ? 
_pdbx_entry_details.nonpolymer_details       ? 
_pdbx_entry_details.sequence_details         ? 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 C   LLL THR 76 ? ? O   LLL HOH 401 ? ? 1.61 
2 1 ND2 HHH ASN 33 ? ? NH1 HHH ARG 101 ? ? 2.04 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR HHH 16  ? ? -106.48 -154.62 
2  1 CYS HHH 22  ? ? -166.07 94.02   
3  1 PHE HHH 29  ? ? 76.70   -63.71  
4  1 LYS HHH 43  ? ? -101.05 -166.52 
5  1 ARG HHH 101 ? ? 78.36   -47.10  
6  1 ASP HHH 148 ? ? 62.48   70.26   
7  1 THR HHH 164 ? ? -140.28 -25.64  
8  1 SER HHH 181 ? ? -162.83 116.91  
9  1 THR HHH 195 ? ? -121.50 -77.62  
10 1 HIS HHH 204 ? ? -150.32 73.83   
11 1 ASP LLL 36  ? ? -95.06  55.26   
12 1 SER LLL 56  ? ? -173.95 -47.93  
13 1 SER LLL 69  ? ? -170.45 -116.78 
14 1 GLU LLL 85  ? ? -64.96  0.52    
15 1 ALA LLL 148 ? ? -165.58 114.33  
16 1 GLN LLL 170 ? ? -38.82  130.56  
17 1 LYS LLL 173 ? ? -74.51  -73.48  
18 1 SER LLL 175 ? ? 59.19   17.09   
19 1 LYS LLL 194 ? ? -116.59 -71.04  
20 1 CYS LLL 198 ? ? -170.78 100.98  
21 1 HIS LLL 202 ? ? -172.91 145.60  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   SER 
_pdbx_validate_peptide_omega.auth_asym_id_1   LLL 
_pdbx_validate_peptide_omega.auth_seq_id_1    69 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   GLY 
_pdbx_validate_peptide_omega.auth_asym_id_2   LLL 
_pdbx_validate_peptide_omega.auth_seq_id_2    70 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -147.69 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 HHH GLU 1   ? CG  ? A GLU 1   CG  
2   1 Y 1 HHH GLU 1   ? CD  ? A GLU 1   CD  
3   1 Y 1 HHH GLU 1   ? OE1 ? A GLU 1   OE1 
4   1 Y 1 HHH GLU 1   ? OE2 ? A GLU 1   OE2 
5   1 Y 1 HHH LYS 19  ? CG  ? A LYS 19  CG  
6   1 Y 1 HHH LYS 19  ? CD  ? A LYS 19  CD  
7   1 Y 1 HHH LYS 19  ? CE  ? A LYS 19  CE  
8   1 Y 1 HHH LYS 19  ? NZ  ? A LYS 19  NZ  
9   1 Y 1 HHH LYS 23  ? CG  ? A LYS 23  CG  
10  1 Y 1 HHH LYS 23  ? CD  ? A LYS 23  CD  
11  1 Y 1 HHH LYS 23  ? CE  ? A LYS 23  CE  
12  1 Y 1 HHH LYS 23  ? NZ  ? A LYS 23  NZ  
13  1 Y 1 HHH ASP 31  ? CG  ? A ASP 31  CG  
14  1 Y 1 HHH ASP 31  ? OD1 ? A ASP 31  OD1 
15  1 Y 1 HHH ASP 31  ? OD2 ? A ASP 31  OD2 
16  1 Y 1 HHH LYS 43  ? CG  ? A LYS 43  CG  
17  1 Y 1 HHH LYS 43  ? CD  ? A LYS 43  CD  
18  1 Y 1 HHH LYS 43  ? CE  ? A LYS 43  CE  
19  1 Y 1 HHH LYS 43  ? NZ  ? A LYS 43  NZ  
20  1 Y 1 HHH LYS 63  ? CG  ? A LYS 63  CG  
21  1 Y 1 HHH LYS 63  ? CD  ? A LYS 63  CD  
22  1 Y 1 HHH LYS 63  ? CE  ? A LYS 63  CE  
23  1 Y 1 HHH LYS 63  ? NZ  ? A LYS 63  NZ  
24  1 Y 1 HHH LYS 65  ? CG  ? A LYS 65  CG  
25  1 Y 1 HHH LYS 65  ? CD  ? A LYS 65  CD  
26  1 Y 1 HHH LYS 65  ? CE  ? A LYS 65  CE  
27  1 Y 1 HHH LYS 65  ? NZ  ? A LYS 65  NZ  
28  1 Y 1 HHH ASP 73  ? CG  ? A ASP 73  CG  
29  1 Y 1 HHH ASP 73  ? OD1 ? A ASP 73  OD1 
30  1 Y 1 HHH ASP 73  ? OD2 ? A ASP 73  OD2 
31  1 Y 1 HHH LYS 74  ? CG  ? A LYS 74  CG  
32  1 Y 1 HHH LYS 74  ? CD  ? A LYS 74  CD  
33  1 Y 1 HHH LYS 74  ? CE  ? A LYS 74  CE  
34  1 Y 1 HHH LYS 74  ? NZ  ? A LYS 74  NZ  
35  1 Y 1 HHH LYS 205 ? CG  ? A LYS 205 CG  
36  1 Y 1 HHH LYS 205 ? CD  ? A LYS 205 CD  
37  1 Y 1 HHH LYS 205 ? CE  ? A LYS 205 CE  
38  1 Y 1 HHH LYS 205 ? NZ  ? A LYS 205 NZ  
39  1 Y 1 HHH LYS 210 ? CG  ? A LYS 210 CG  
40  1 Y 1 HHH LYS 210 ? CD  ? A LYS 210 CD  
41  1 Y 1 HHH LYS 210 ? CE  ? A LYS 210 CE  
42  1 Y 1 HHH LYS 210 ? NZ  ? A LYS 210 NZ  
43  1 Y 1 HHH LYS 213 ? CG  ? A LYS 213 CG  
44  1 Y 1 HHH LYS 213 ? CD  ? A LYS 213 CD  
45  1 Y 1 HHH LYS 213 ? CE  ? A LYS 213 CE  
46  1 Y 1 HHH LYS 213 ? NZ  ? A LYS 213 NZ  
47  1 Y 1 HHH ARG 214 ? CG  ? A ARG 214 CG  
48  1 Y 1 HHH ARG 214 ? CD  ? A ARG 214 CD  
49  1 Y 1 HHH ARG 214 ? NE  ? A ARG 214 NE  
50  1 Y 1 HHH ARG 214 ? CZ  ? A ARG 214 CZ  
51  1 Y 1 HHH ARG 214 ? NH1 ? A ARG 214 NH1 
52  1 Y 1 HHH ARG 214 ? NH2 ? A ARG 214 NH2 
53  1 Y 1 HHH GLU 216 ? CG  ? A GLU 216 CG  
54  1 Y 1 HHH GLU 216 ? CD  ? A GLU 216 CD  
55  1 Y 1 HHH GLU 216 ? OE1 ? A GLU 216 OE1 
56  1 Y 1 HHH GLU 216 ? OE2 ? A GLU 216 OE2 
57  1 Y 1 HHH LYS 218 ? CG  ? A LYS 218 CG  
58  1 Y 1 HHH LYS 218 ? CD  ? A LYS 218 CD  
59  1 Y 1 HHH LYS 218 ? CE  ? A LYS 218 CE  
60  1 Y 1 HHH LYS 218 ? NZ  ? A LYS 218 NZ  
61  1 Y 1 LLL THR 76  ? O   ? B THR 76  O   
62  1 Y 1 LLL GLU 84  ? CG  ? B GLU 84  CG  
63  1 Y 1 LLL GLU 84  ? CD  ? B GLU 84  CD  
64  1 Y 1 LLL GLU 84  ? OE1 ? B GLU 84  OE1 
65  1 Y 1 LLL GLU 84  ? OE2 ? B GLU 84  OE2 
66  1 Y 1 LLL ARG 112 ? CG  ? B ARG 112 CG  
67  1 Y 1 LLL ARG 112 ? CD  ? B ARG 112 CD  
68  1 Y 1 LLL ARG 112 ? NE  ? B ARG 112 NE  
69  1 Y 1 LLL ARG 112 ? CZ  ? B ARG 112 CZ  
70  1 Y 1 LLL ARG 112 ? NH1 ? B ARG 112 NH1 
71  1 Y 1 LLL ARG 112 ? NH2 ? B ARG 112 NH2 
72  1 Y 1 LLL ASP 126 ? CG  ? B ASP 126 CG  
73  1 Y 1 LLL ASP 126 ? OD1 ? B ASP 126 OD1 
74  1 Y 1 LLL ASP 126 ? OD2 ? B ASP 126 OD2 
75  1 Y 1 LLL LYS 130 ? CG  ? B LYS 130 CG  
76  1 Y 1 LLL LYS 130 ? CD  ? B LYS 130 CD  
77  1 Y 1 LLL LYS 130 ? CE  ? B LYS 130 CE  
78  1 Y 1 LLL LYS 130 ? NZ  ? B LYS 130 NZ  
79  1 Y 1 LLL GLU 147 ? CG  ? B GLU 147 CG  
80  1 Y 1 LLL GLU 147 ? CD  ? B GLU 147 CD  
81  1 Y 1 LLL GLU 147 ? OE1 ? B GLU 147 OE1 
82  1 Y 1 LLL GLU 147 ? OE2 ? B GLU 147 OE2 
83  1 Y 1 LLL LYS 149 ? CG  ? B LYS 149 CG  
84  1 Y 1 LLL LYS 149 ? CD  ? B LYS 149 CD  
85  1 Y 1 LLL LYS 149 ? CE  ? B LYS 149 CE  
86  1 Y 1 LLL LYS 149 ? NZ  ? B LYS 149 NZ  
87  1 Y 1 LLL LYS 153 ? CG  ? B LYS 153 CG  
88  1 Y 1 LLL LYS 153 ? CD  ? B LYS 153 CD  
89  1 Y 1 LLL LYS 153 ? CE  ? B LYS 153 CE  
90  1 Y 1 LLL LYS 153 ? NZ  ? B LYS 153 NZ  
91  1 Y 1 LLL GLN 164 ? CG  ? B GLN 164 CG  
92  1 Y 1 LLL GLN 164 ? CD  ? B GLN 164 CD  
93  1 Y 1 LLL GLN 164 ? OE1 ? B GLN 164 OE1 
94  1 Y 1 LLL GLN 164 ? NE2 ? B GLN 164 NE2 
95  1 Y 1 LLL GLU 169 ? CG  ? B GLU 169 CG  
96  1 Y 1 LLL GLU 169 ? CD  ? B GLU 169 CD  
97  1 Y 1 LLL GLU 169 ? OE1 ? B GLU 169 OE1 
98  1 Y 1 LLL GLU 169 ? OE2 ? B GLU 169 OE2 
99  1 Y 1 LLL LYS 173 ? CG  ? B LYS 173 CG  
100 1 Y 1 LLL LYS 173 ? CD  ? B LYS 173 CD  
101 1 Y 1 LLL LYS 173 ? CE  ? B LYS 173 CE  
102 1 Y 1 LLL LYS 173 ? NZ  ? B LYS 173 NZ  
103 1 Y 1 LLL LYS 187 ? CG  ? B LYS 187 CG  
104 1 Y 1 LLL LYS 187 ? CD  ? B LYS 187 CD  
105 1 Y 1 LLL LYS 187 ? CE  ? B LYS 187 CE  
106 1 Y 1 LLL LYS 187 ? NZ  ? B LYS 187 NZ  
107 1 Y 1 LLL GLU 191 ? CG  ? B GLU 191 CG  
108 1 Y 1 LLL GLU 191 ? CD  ? B GLU 191 CD  
109 1 Y 1 LLL GLU 191 ? OE1 ? B GLU 191 OE1 
110 1 Y 1 LLL GLU 191 ? OE2 ? B GLU 191 OE2 
111 1 Y 1 LLL LYS 192 ? CG  ? B LYS 192 CG  
112 1 Y 1 LLL LYS 192 ? CD  ? B LYS 192 CD  
113 1 Y 1 LLL LYS 192 ? CE  ? B LYS 192 CE  
114 1 Y 1 LLL LYS 192 ? NZ  ? B LYS 192 NZ  
115 1 Y 1 LLL LYS 194 ? CG  ? B LYS 194 CG  
116 1 Y 1 LLL LYS 194 ? CD  ? B LYS 194 CD  
117 1 Y 1 LLL LYS 194 ? CE  ? B LYS 194 CE  
118 1 Y 1 LLL LYS 194 ? NZ  ? B LYS 194 NZ  
119 1 Y 1 LLL ASN 214 ? CG  ? B ASN 214 CG  
120 1 Y 1 LLL ASN 214 ? OD1 ? B ASN 214 OD1 
121 1 Y 1 LLL ASN 214 ? ND2 ? B ASN 214 ND2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 HHH LYS 133 ? A LYS 133 
2  1 Y 1 HHH SER 134 ? A SER 134 
3  1 Y 1 HHH THR 135 ? A THR 135 
4  1 Y 1 HHH SER 136 ? A SER 136 
5  1 Y 1 HHH GLY 137 ? A GLY 137 
6  1 Y 1 HHH GLY 138 ? A GLY 138 
7  1 Y 1 HHH CYS 220 ? A CYS 220 
8  1 Y 1 HHH ASP 221 ? A ASP 221 
9  1 Y 1 HHH LYS 222 ? A LYS 222 
10 1 Y 1 HHH THR 223 ? A THR 223 
11 1 Y 1 LLL GLU 217 ? B GLU 217 
12 1 Y 1 LLL CYS 218 ? B CYS 218 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EDO C1   C N N 88  
EDO O1   O N N 89  
EDO C2   C N N 90  
EDO O2   O N N 91  
EDO H11  H N N 92  
EDO H12  H N N 93  
EDO HO1  H N N 94  
EDO H21  H N N 95  
EDO H22  H N N 96  
EDO HO2  H N N 97  
GLN N    N N N 98  
GLN CA   C N S 99  
GLN C    C N N 100 
GLN O    O N N 101 
GLN CB   C N N 102 
GLN CG   C N N 103 
GLN CD   C N N 104 
GLN OE1  O N N 105 
GLN NE2  N N N 106 
GLN OXT  O N N 107 
GLN H    H N N 108 
GLN H2   H N N 109 
GLN HA   H N N 110 
GLN HB2  H N N 111 
GLN HB3  H N N 112 
GLN HG2  H N N 113 
GLN HG3  H N N 114 
GLN HE21 H N N 115 
GLN HE22 H N N 116 
GLN HXT  H N N 117 
GLU N    N N N 118 
GLU CA   C N S 119 
GLU C    C N N 120 
GLU O    O N N 121 
GLU CB   C N N 122 
GLU CG   C N N 123 
GLU CD   C N N 124 
GLU OE1  O N N 125 
GLU OE2  O N N 126 
GLU OXT  O N N 127 
GLU H    H N N 128 
GLU H2   H N N 129 
GLU HA   H N N 130 
GLU HB2  H N N 131 
GLU HB3  H N N 132 
GLU HG2  H N N 133 
GLU HG3  H N N 134 
GLU HE2  H N N 135 
GLU HXT  H N N 136 
GLY N    N N N 137 
GLY CA   C N N 138 
GLY C    C N N 139 
GLY O    O N N 140 
GLY OXT  O N N 141 
GLY H    H N N 142 
GLY H2   H N N 143 
GLY HA2  H N N 144 
GLY HA3  H N N 145 
GLY HXT  H N N 146 
HIS N    N N N 147 
HIS CA   C N S 148 
HIS C    C N N 149 
HIS O    O N N 150 
HIS CB   C N N 151 
HIS CG   C Y N 152 
HIS ND1  N Y N 153 
HIS CD2  C Y N 154 
HIS CE1  C Y N 155 
HIS NE2  N Y N 156 
HIS OXT  O N N 157 
HIS H    H N N 158 
HIS H2   H N N 159 
HIS HA   H N N 160 
HIS HB2  H N N 161 
HIS HB3  H N N 162 
HIS HD1  H N N 163 
HIS HD2  H N N 164 
HIS HE1  H N N 165 
HIS HE2  H N N 166 
HIS HXT  H N N 167 
HOH O    O N N 168 
HOH H1   H N N 169 
HOH H2   H N N 170 
ILE N    N N N 171 
ILE CA   C N S 172 
ILE C    C N N 173 
ILE O    O N N 174 
ILE CB   C N S 175 
ILE CG1  C N N 176 
ILE CG2  C N N 177 
ILE CD1  C N N 178 
ILE OXT  O N N 179 
ILE H    H N N 180 
ILE H2   H N N 181 
ILE HA   H N N 182 
ILE HB   H N N 183 
ILE HG12 H N N 184 
ILE HG13 H N N 185 
ILE HG21 H N N 186 
ILE HG22 H N N 187 
ILE HG23 H N N 188 
ILE HD11 H N N 189 
ILE HD12 H N N 190 
ILE HD13 H N N 191 
ILE HXT  H N N 192 
LEU N    N N N 193 
LEU CA   C N S 194 
LEU C    C N N 195 
LEU O    O N N 196 
LEU CB   C N N 197 
LEU CG   C N N 198 
LEU CD1  C N N 199 
LEU CD2  C N N 200 
LEU OXT  O N N 201 
LEU H    H N N 202 
LEU H2   H N N 203 
LEU HA   H N N 204 
LEU HB2  H N N 205 
LEU HB3  H N N 206 
LEU HG   H N N 207 
LEU HD11 H N N 208 
LEU HD12 H N N 209 
LEU HD13 H N N 210 
LEU HD21 H N N 211 
LEU HD22 H N N 212 
LEU HD23 H N N 213 
LEU HXT  H N N 214 
LYS N    N N N 215 
LYS CA   C N S 216 
LYS C    C N N 217 
LYS O    O N N 218 
LYS CB   C N N 219 
LYS CG   C N N 220 
LYS CD   C N N 221 
LYS CE   C N N 222 
LYS NZ   N N N 223 
LYS OXT  O N N 224 
LYS H    H N N 225 
LYS H2   H N N 226 
LYS HA   H N N 227 
LYS HB2  H N N 228 
LYS HB3  H N N 229 
LYS HG2  H N N 230 
LYS HG3  H N N 231 
LYS HD2  H N N 232 
LYS HD3  H N N 233 
LYS HE2  H N N 234 
LYS HE3  H N N 235 
LYS HZ1  H N N 236 
LYS HZ2  H N N 237 
LYS HZ3  H N N 238 
LYS HXT  H N N 239 
MET N    N N N 240 
MET CA   C N S 241 
MET C    C N N 242 
MET O    O N N 243 
MET CB   C N N 244 
MET CG   C N N 245 
MET SD   S N N 246 
MET CE   C N N 247 
MET OXT  O N N 248 
MET H    H N N 249 
MET H2   H N N 250 
MET HA   H N N 251 
MET HB2  H N N 252 
MET HB3  H N N 253 
MET HG2  H N N 254 
MET HG3  H N N 255 
MET HE1  H N N 256 
MET HE2  H N N 257 
MET HE3  H N N 258 
MET HXT  H N N 259 
PHE N    N N N 260 
PHE CA   C N S 261 
PHE C    C N N 262 
PHE O    O N N 263 
PHE CB   C N N 264 
PHE CG   C Y N 265 
PHE CD1  C Y N 266 
PHE CD2  C Y N 267 
PHE CE1  C Y N 268 
PHE CE2  C Y N 269 
PHE CZ   C Y N 270 
PHE OXT  O N N 271 
PHE H    H N N 272 
PHE H2   H N N 273 
PHE HA   H N N 274 
PHE HB2  H N N 275 
PHE HB3  H N N 276 
PHE HD1  H N N 277 
PHE HD2  H N N 278 
PHE HE1  H N N 279 
PHE HE2  H N N 280 
PHE HZ   H N N 281 
PHE HXT  H N N 282 
PRO N    N N N 283 
PRO CA   C N S 284 
PRO C    C N N 285 
PRO O    O N N 286 
PRO CB   C N N 287 
PRO CG   C N N 288 
PRO CD   C N N 289 
PRO OXT  O N N 290 
PRO H    H N N 291 
PRO HA   H N N 292 
PRO HB2  H N N 293 
PRO HB3  H N N 294 
PRO HG2  H N N 295 
PRO HG3  H N N 296 
PRO HD2  H N N 297 
PRO HD3  H N N 298 
PRO HXT  H N N 299 
SER N    N N N 300 
SER CA   C N S 301 
SER C    C N N 302 
SER O    O N N 303 
SER CB   C N N 304 
SER OG   O N N 305 
SER OXT  O N N 306 
SER H    H N N 307 
SER H2   H N N 308 
SER HA   H N N 309 
SER HB2  H N N 310 
SER HB3  H N N 311 
SER HG   H N N 312 
SER HXT  H N N 313 
THR N    N N N 314 
THR CA   C N S 315 
THR C    C N N 316 
THR O    O N N 317 
THR CB   C N R 318 
THR OG1  O N N 319 
THR CG2  C N N 320 
THR OXT  O N N 321 
THR H    H N N 322 
THR H2   H N N 323 
THR HA   H N N 324 
THR HB   H N N 325 
THR HG1  H N N 326 
THR HG21 H N N 327 
THR HG22 H N N 328 
THR HG23 H N N 329 
THR HXT  H N N 330 
TRP N    N N N 331 
TRP CA   C N S 332 
TRP C    C N N 333 
TRP O    O N N 334 
TRP CB   C N N 335 
TRP CG   C Y N 336 
TRP CD1  C Y N 337 
TRP CD2  C Y N 338 
TRP NE1  N Y N 339 
TRP CE2  C Y N 340 
TRP CE3  C Y N 341 
TRP CZ2  C Y N 342 
TRP CZ3  C Y N 343 
TRP CH2  C Y N 344 
TRP OXT  O N N 345 
TRP H    H N N 346 
TRP H2   H N N 347 
TRP HA   H N N 348 
TRP HB2  H N N 349 
TRP HB3  H N N 350 
TRP HD1  H N N 351 
TRP HE1  H N N 352 
TRP HE3  H N N 353 
TRP HZ2  H N N 354 
TRP HZ3  H N N 355 
TRP HH2  H N N 356 
TRP HXT  H N N 357 
TYR N    N N N 358 
TYR CA   C N S 359 
TYR C    C N N 360 
TYR O    O N N 361 
TYR CB   C N N 362 
TYR CG   C Y N 363 
TYR CD1  C Y N 364 
TYR CD2  C Y N 365 
TYR CE1  C Y N 366 
TYR CE2  C Y N 367 
TYR CZ   C Y N 368 
TYR OH   O N N 369 
TYR OXT  O N N 370 
TYR H    H N N 371 
TYR H2   H N N 372 
TYR HA   H N N 373 
TYR HB2  H N N 374 
TYR HB3  H N N 375 
TYR HD1  H N N 376 
TYR HD2  H N N 377 
TYR HE1  H N N 378 
TYR HE2  H N N 379 
TYR HH   H N N 380 
TYR HXT  H N N 381 
VAL N    N N N 382 
VAL CA   C N S 383 
VAL C    C N N 384 
VAL O    O N N 385 
VAL CB   C N N 386 
VAL CG1  C N N 387 
VAL CG2  C N N 388 
VAL OXT  O N N 389 
VAL H    H N N 390 
VAL H2   H N N 391 
VAL HA   H N N 392 
VAL HB   H N N 393 
VAL HG11 H N N 394 
VAL HG12 H N N 395 
VAL HG13 H N N 396 
VAL HG21 H N N 397 
VAL HG22 H N N 398 
VAL HG23 H N N 399 
VAL HXT  H N N 400 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PHE N   CA   sing N N 246 
PHE N   H    sing N N 247 
PHE N   H2   sing N N 248 
PHE CA  C    sing N N 249 
PHE CA  CB   sing N N 250 
PHE CA  HA   sing N N 251 
PHE C   O    doub N N 252 
PHE C   OXT  sing N N 253 
PHE CB  CG   sing N N 254 
PHE CB  HB2  sing N N 255 
PHE CB  HB3  sing N N 256 
PHE CG  CD1  doub Y N 257 
PHE CG  CD2  sing Y N 258 
PHE CD1 CE1  sing Y N 259 
PHE CD1 HD1  sing N N 260 
PHE CD2 CE2  doub Y N 261 
PHE CD2 HD2  sing N N 262 
PHE CE1 CZ   doub Y N 263 
PHE CE1 HE1  sing N N 264 
PHE CE2 CZ   sing Y N 265 
PHE CE2 HE2  sing N N 266 
PHE CZ  HZ   sing N N 267 
PHE OXT HXT  sing N N 268 
PRO N   CA   sing N N 269 
PRO N   CD   sing N N 270 
PRO N   H    sing N N 271 
PRO CA  C    sing N N 272 
PRO CA  CB   sing N N 273 
PRO CA  HA   sing N N 274 
PRO C   O    doub N N 275 
PRO C   OXT  sing N N 276 
PRO CB  CG   sing N N 277 
PRO CB  HB2  sing N N 278 
PRO CB  HB3  sing N N 279 
PRO CG  CD   sing N N 280 
PRO CG  HG2  sing N N 281 
PRO CG  HG3  sing N N 282 
PRO CD  HD2  sing N N 283 
PRO CD  HD3  sing N N 284 
PRO OXT HXT  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
THR N   CA   sing N N 299 
THR N   H    sing N N 300 
THR N   H2   sing N N 301 
THR CA  C    sing N N 302 
THR CA  CB   sing N N 303 
THR CA  HA   sing N N 304 
THR C   O    doub N N 305 
THR C   OXT  sing N N 306 
THR CB  OG1  sing N N 307 
THR CB  CG2  sing N N 308 
THR CB  HB   sing N N 309 
THR OG1 HG1  sing N N 310 
THR CG2 HG21 sing N N 311 
THR CG2 HG22 sing N N 312 
THR CG2 HG23 sing N N 313 
THR OXT HXT  sing N N 314 
TRP N   CA   sing N N 315 
TRP N   H    sing N N 316 
TRP N   H2   sing N N 317 
TRP CA  C    sing N N 318 
TRP CA  CB   sing N N 319 
TRP CA  HA   sing N N 320 
TRP C   O    doub N N 321 
TRP C   OXT  sing N N 322 
TRP CB  CG   sing N N 323 
TRP CB  HB2  sing N N 324 
TRP CB  HB3  sing N N 325 
TRP CG  CD1  doub Y N 326 
TRP CG  CD2  sing Y N 327 
TRP CD1 NE1  sing Y N 328 
TRP CD1 HD1  sing N N 329 
TRP CD2 CE2  doub Y N 330 
TRP CD2 CE3  sing Y N 331 
TRP NE1 CE2  sing Y N 332 
TRP NE1 HE1  sing N N 333 
TRP CE2 CZ2  sing Y N 334 
TRP CE3 CZ3  doub Y N 335 
TRP CE3 HE3  sing N N 336 
TRP CZ2 CH2  doub Y N 337 
TRP CZ2 HZ2  sing N N 338 
TRP CZ3 CH2  sing Y N 339 
TRP CZ3 HZ3  sing N N 340 
TRP CH2 HH2  sing N N 341 
TRP OXT HXT  sing N N 342 
TYR N   CA   sing N N 343 
TYR N   H    sing N N 344 
TYR N   H2   sing N N 345 
TYR CA  C    sing N N 346 
TYR CA  CB   sing N N 347 
TYR CA  HA   sing N N 348 
TYR C   O    doub N N 349 
TYR C   OXT  sing N N 350 
TYR CB  CG   sing N N 351 
TYR CB  HB2  sing N N 352 
TYR CB  HB3  sing N N 353 
TYR CG  CD1  doub Y N 354 
TYR CG  CD2  sing Y N 355 
TYR CD1 CE1  sing Y N 356 
TYR CD1 HD1  sing N N 357 
TYR CD2 CE2  doub Y N 358 
TYR CD2 HD2  sing N N 359 
TYR CE1 CZ   doub Y N 360 
TYR CE1 HE1  sing N N 361 
TYR CE2 CZ   sing Y N 362 
TYR CE2 HE2  sing N N 363 
TYR CZ  OH   sing N N 364 
TYR OH  HH   sing N N 365 
TYR OXT HXT  sing N N 366 
VAL N   CA   sing N N 367 
VAL N   H    sing N N 368 
VAL N   H2   sing N N 369 
VAL CA  C    sing N N 370 
VAL CA  CB   sing N N 371 
VAL CA  HA   sing N N 372 
VAL C   O    doub N N 373 
VAL C   OXT  sing N N 374 
VAL CB  CG1  sing N N 375 
VAL CB  CG2  sing N N 376 
VAL CB  HB   sing N N 377 
VAL CG1 HG11 sing N N 378 
VAL CG1 HG12 sing N N 379 
VAL CG1 HG13 sing N N 380 
VAL CG2 HG21 sing N N 381 
VAL CG2 HG22 sing N N 382 
VAL CG2 HG23 sing N N 383 
VAL OXT HXT  sing N N 384 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           AI144422 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        EDO 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   EDO 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 1,2-ETHANEDIOL EDO 
4 water          HOH 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6WKM 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
