data_8RDF
# 
_entry.id   8RDF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.392 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8RDF         pdb_00008rdf 10.2210/pdb8rdf/pdb 
WWPDB D_1292135224 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-05-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8RDF 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          8RDA 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              lucia.x.dello-iacono@gsk.com 
_pdbx_contact_author.name_first         Lucia 
_pdbx_contact_author.name_last          'Dello Iacono' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2867-283X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Nonne, F.'        1 ? 
'Dello Iacono, L.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Cent.Sci.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2374-7951 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;A Multidisciplinary Structural Approach to the Identification of the Haemophilus influenzae Type b Capsular Polysaccharide Protective Epitope
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscentsci.3c01515 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Nonne, F.'           1  ? 
primary 'Iacono, L.D.'        2  ? 
primary 'Bertuzzi, S.'        3  ? 
primary 'Unione, L.'          4  ? 
primary 'Proietti, D.'        5  ? 
primary 'Norais, N.'          6  ? 
primary 'Margarit, I.'        7  ? 
primary 'Adamo, R.'           8  ? 
primary 'Jimenez-Barbero, J.' 9  ? 
primary 'Carboni, F.'         10 ? 
primary 'Romano, M.R.'        11 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Fab CA4 H chain'                                         23861.680 1  ? ? ? ? 
2 polymer     man 'Fab CA4 L chain'                                         23680.264 1  ? ? ? ? 
3 non-polymer syn 'Haemophilus influenzae type b (Hib) DP3 oligosaccharide' 1056.690  1  ? ? ? ? 
4 non-polymer syn 'ZINC ION'                                                65.409    1  ? ? ? ? 
5 water       nat water                                                     18.015    54 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVQLVESGGGLVTPGGSLRLSCAASGFTFNTYSMNWVRQAPGKGLEWVSSISRSSDYIYYADSVKGRFTISRDNAKNSVY
LQMTSLRDEDTAVYYCARDPGGMPTTVTTWLYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
;
;EVQLVESGGGLVTPGGSLRLSCAASGFTFNTYSMNWVRQAPGKGLEWVSSISRSSDYIYYADSVKGRFTISRDNAKNSVY
LQMTSLRDEDTAVYYCARDPGGMPTTVTTWLYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
;
H ? 
2 'polypeptide(L)' no no 
;EIVLTQSPGTLSLSPGERATLSCRASQSVTSNYLAWYQQKPGQAPRLLIYDTSRRATGIPDRFSGSGSATDFTLTISRLE
PDDFAIYYCQQYGSSPPVTFGHGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGN
SQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;EIVLTQSPGTLSLSPGERATLSCRASQSVTSNYLAWYQQKPGQAPRLLIYDTSRRATGIPDRFSGSGSATDFTLTISRLE
PDDFAIYYCQQYGSSPPVTFGHGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGN
SQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'Haemophilus influenzae type b (Hib) DP3 oligosaccharide' A1H09 
4 'ZINC ION'                                                ZN    
5 water                                                     HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  THR n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  ARG n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  ALA n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  THR n 
1 29  PHE n 
1 30  ASN n 
1 31  THR n 
1 32  TYR n 
1 33  SER n 
1 34  MET n 
1 35  ASN n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  VAL n 
1 49  SER n 
1 50  SER n 
1 51  ILE n 
1 52  SER n 
1 53  ARG n 
1 54  SER n 
1 55  SER n 
1 56  ASP n 
1 57  TYR n 
1 58  ILE n 
1 59  TYR n 
1 60  TYR n 
1 61  ALA n 
1 62  ASP n 
1 63  SER n 
1 64  VAL n 
1 65  LYS n 
1 66  GLY n 
1 67  ARG n 
1 68  PHE n 
1 69  THR n 
1 70  ILE n 
1 71  SER n 
1 72  ARG n 
1 73  ASP n 
1 74  ASN n 
1 75  ALA n 
1 76  LYS n 
1 77  ASN n 
1 78  SER n 
1 79  VAL n 
1 80  TYR n 
1 81  LEU n 
1 82  GLN n 
1 83  MET n 
1 84  THR n 
1 85  SER n 
1 86  LEU n 
1 87  ARG n 
1 88  ASP n 
1 89  GLU n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  VAL n 
1 94  TYR n 
1 95  TYR n 
1 96  CYS n 
1 97  ALA n 
1 98  ARG n 
1 99  ASP n 
1 100 PRO n 
1 101 GLY n 
1 102 GLY n 
1 103 MET n 
1 104 PRO n 
1 105 THR n 
1 106 THR n 
1 107 VAL n 
1 108 THR n 
1 109 THR n 
1 110 TRP n 
1 111 LEU n 
1 112 TYR n 
1 113 TRP n 
1 114 GLY n 
1 115 GLN n 
1 116 GLY n 
1 117 THR n 
1 118 LEU n 
1 119 VAL n 
1 120 THR n 
1 121 VAL n 
1 122 SER n 
1 123 SER n 
1 124 ALA n 
1 125 SER n 
1 126 THR n 
1 127 LYS n 
1 128 GLY n 
1 129 PRO n 
1 130 SER n 
1 131 VAL n 
1 132 PHE n 
1 133 PRO n 
1 134 LEU n 
1 135 ALA n 
1 136 PRO n 
1 137 SER n 
1 138 SER n 
1 139 LYS n 
1 140 SER n 
1 141 THR n 
1 142 SER n 
1 143 GLY n 
1 144 GLY n 
1 145 THR n 
1 146 ALA n 
1 147 ALA n 
1 148 LEU n 
1 149 GLY n 
1 150 CYS n 
1 151 LEU n 
1 152 VAL n 
1 153 LYS n 
1 154 ASP n 
1 155 TYR n 
1 156 PHE n 
1 157 PRO n 
1 158 GLU n 
1 159 PRO n 
1 160 VAL n 
1 161 THR n 
1 162 VAL n 
1 163 SER n 
1 164 TRP n 
1 165 ASN n 
1 166 SER n 
1 167 GLY n 
1 168 ALA n 
1 169 LEU n 
1 170 THR n 
1 171 SER n 
1 172 GLY n 
1 173 VAL n 
1 174 HIS n 
1 175 THR n 
1 176 PHE n 
1 177 PRO n 
1 178 ALA n 
1 179 VAL n 
1 180 LEU n 
1 181 GLN n 
1 182 SER n 
1 183 SER n 
1 184 GLY n 
1 185 LEU n 
1 186 TYR n 
1 187 SER n 
1 188 LEU n 
1 189 SER n 
1 190 SER n 
1 191 VAL n 
1 192 VAL n 
1 193 THR n 
1 194 VAL n 
1 195 PRO n 
1 196 SER n 
1 197 SER n 
1 198 SER n 
1 199 LEU n 
1 200 GLY n 
1 201 THR n 
1 202 GLN n 
1 203 THR n 
1 204 TYR n 
1 205 ILE n 
1 206 CYS n 
1 207 ASN n 
1 208 VAL n 
1 209 ASN n 
1 210 HIS n 
1 211 LYS n 
1 212 PRO n 
1 213 SER n 
1 214 ASN n 
1 215 THR n 
1 216 LYS n 
1 217 VAL n 
1 218 ASP n 
1 219 LYS n 
1 220 ARG n 
1 221 VAL n 
1 222 GLU n 
1 223 PRO n 
1 224 LYS n 
2 1   GLU n 
2 2   ILE n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   GLY n 
2 10  THR n 
2 11  LEU n 
2 12  SER n 
2 13  LEU n 
2 14  SER n 
2 15  PRO n 
2 16  GLY n 
2 17  GLU n 
2 18  ARG n 
2 19  ALA n 
2 20  THR n 
2 21  LEU n 
2 22  SER n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  SER n 
2 29  VAL n 
2 30  THR n 
2 31  SER n 
2 32  ASN n 
2 33  TYR n 
2 34  LEU n 
2 35  ALA n 
2 36  TRP n 
2 37  TYR n 
2 38  GLN n 
2 39  GLN n 
2 40  LYS n 
2 41  PRO n 
2 42  GLY n 
2 43  GLN n 
2 44  ALA n 
2 45  PRO n 
2 46  ARG n 
2 47  LEU n 
2 48  LEU n 
2 49  ILE n 
2 50  TYR n 
2 51  ASP n 
2 52  THR n 
2 53  SER n 
2 54  ARG n 
2 55  ARG n 
2 56  ALA n 
2 57  THR n 
2 58  GLY n 
2 59  ILE n 
2 60  PRO n 
2 61  ASP n 
2 62  ARG n 
2 63  PHE n 
2 64  SER n 
2 65  GLY n 
2 66  SER n 
2 67  GLY n 
2 68  SER n 
2 69  ALA n 
2 70  THR n 
2 71  ASP n 
2 72  PHE n 
2 73  THR n 
2 74  LEU n 
2 75  THR n 
2 76  ILE n 
2 77  SER n 
2 78  ARG n 
2 79  LEU n 
2 80  GLU n 
2 81  PRO n 
2 82  ASP n 
2 83  ASP n 
2 84  PHE n 
2 85  ALA n 
2 86  ILE n 
2 87  TYR n 
2 88  TYR n 
2 89  CYS n 
2 90  GLN n 
2 91  GLN n 
2 92  TYR n 
2 93  GLY n 
2 94  SER n 
2 95  SER n 
2 96  PRO n 
2 97  PRO n 
2 98  VAL n 
2 99  THR n 
2 100 PHE n 
2 101 GLY n 
2 102 HIS n 
2 103 GLY n 
2 104 THR n 
2 105 LYS n 
2 106 VAL n 
2 107 GLU n 
2 108 ILE n 
2 109 LYS n 
2 110 ARG n 
2 111 THR n 
2 112 VAL n 
2 113 ALA n 
2 114 ALA n 
2 115 PRO n 
2 116 SER n 
2 117 VAL n 
2 118 PHE n 
2 119 ILE n 
2 120 PHE n 
2 121 PRO n 
2 122 PRO n 
2 123 SER n 
2 124 ASP n 
2 125 GLU n 
2 126 GLN n 
2 127 LEU n 
2 128 LYS n 
2 129 SER n 
2 130 GLY n 
2 131 THR n 
2 132 ALA n 
2 133 SER n 
2 134 VAL n 
2 135 VAL n 
2 136 CYS n 
2 137 LEU n 
2 138 LEU n 
2 139 ASN n 
2 140 ASN n 
2 141 PHE n 
2 142 TYR n 
2 143 PRO n 
2 144 ARG n 
2 145 GLU n 
2 146 ALA n 
2 147 LYS n 
2 148 VAL n 
2 149 GLN n 
2 150 TRP n 
2 151 LYS n 
2 152 VAL n 
2 153 ASP n 
2 154 ASN n 
2 155 ALA n 
2 156 LEU n 
2 157 GLN n 
2 158 SER n 
2 159 GLY n 
2 160 ASN n 
2 161 SER n 
2 162 GLN n 
2 163 GLU n 
2 164 SER n 
2 165 VAL n 
2 166 THR n 
2 167 GLU n 
2 168 GLN n 
2 169 ASP n 
2 170 SER n 
2 171 LYS n 
2 172 ASP n 
2 173 SER n 
2 174 THR n 
2 175 TYR n 
2 176 SER n 
2 177 LEU n 
2 178 SER n 
2 179 SER n 
2 180 THR n 
2 181 LEU n 
2 182 THR n 
2 183 LEU n 
2 184 SER n 
2 185 LYS n 
2 186 ALA n 
2 187 ASP n 
2 188 TYR n 
2 189 GLU n 
2 190 LYS n 
2 191 HIS n 
2 192 LYS n 
2 193 VAL n 
2 194 TYR n 
2 195 ALA n 
2 196 CYS n 
2 197 GLU n 
2 198 VAL n 
2 199 THR n 
2 200 HIS n 
2 201 GLN n 
2 202 GLY n 
2 203 LEU n 
2 204 SER n 
2 205 SER n 
2 206 PRO n 
2 207 VAL n 
2 208 THR n 
2 209 LYS n 
2 210 SER n 
2 211 PHE n 
2 212 ASN n 
2 213 ARG n 
2 214 GLY n 
2 215 GLU n 
2 216 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 224 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 216 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1H09 non-polymer         . 'Haemophilus influenzae type b (Hib) DP3 oligosaccharide' 
;[(2~{R},3~{S},4~{R},5~{R})-2-(hydroxymethyl)-4,5-bis(oxidanyl)oxolan-3-yl] [(2~{R},3~{S},4~{S})-5-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-4-[[(2~{R},3~{S},4~{S})-5-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3-oxidanyl-4-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentoxy]phosphoryl]oxy-oxolan-2-yl]oxy-2,3,4-tris(oxidanyl)pentoxy]-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]oxy-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate
;
'C30 H59 O34 P3' 1056.690 
ALA   'L-peptide linking' y ALANINE                                                   ? 'C3 H7 N O2'     89.093   
ARG   'L-peptide linking' y ARGININE                                                  ? 'C6 H15 N4 O2 1' 175.209  
ASN   'L-peptide linking' y ASPARAGINE                                                ? 'C4 H8 N2 O3'    132.118  
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                           ? 'C4 H7 N O4'     133.103  
CYS   'L-peptide linking' y CYSTEINE                                                  ? 'C3 H7 N O2 S'   121.158  
GLN   'L-peptide linking' y GLUTAMINE                                                 ? 'C5 H10 N2 O3'   146.144  
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                           ? 'C5 H9 N O4'     147.129  
GLY   'peptide linking'   y GLYCINE                                                   ? 'C2 H5 N O2'     75.067   
HIS   'L-peptide linking' y HISTIDINE                                                 ? 'C6 H10 N3 O2 1' 156.162  
HOH   non-polymer         . WATER                                                     ? 'H2 O'           18.015   
ILE   'L-peptide linking' y ISOLEUCINE                                                ? 'C6 H13 N O2'    131.173  
LEU   'L-peptide linking' y LEUCINE                                                   ? 'C6 H13 N O2'    131.173  
LYS   'L-peptide linking' y LYSINE                                                    ? 'C6 H15 N2 O2 1' 147.195  
MET   'L-peptide linking' y METHIONINE                                                ? 'C5 H11 N O2 S'  149.211  
PHE   'L-peptide linking' y PHENYLALANINE                                             ? 'C9 H11 N O2'    165.189  
PRO   'L-peptide linking' y PROLINE                                                   ? 'C5 H9 N O2'     115.130  
SER   'L-peptide linking' y SERINE                                                    ? 'C3 H7 N O3'     105.093  
THR   'L-peptide linking' y THREONINE                                                 ? 'C4 H9 N O3'     119.119  
TRP   'L-peptide linking' y TRYPTOPHAN                                                ? 'C11 H12 N2 O2'  204.225  
TYR   'L-peptide linking' y TYROSINE                                                  ? 'C9 H11 N O3'    181.189  
VAL   'L-peptide linking' y VALINE                                                    ? 'C5 H11 N O2'    117.146  
ZN    non-polymer         . 'ZINC ION'                                                ? 'Zn 2'           65.409   
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  THR 13  13  13  THR THR H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  ARG 19  19  19  ARG ARG H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  ALA 23  23  23  ALA ALA H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  THR 28  28  28  THR THR H . n 
A 1 29  PHE 29  29  29  PHE PHE H . n 
A 1 30  ASN 30  30  30  ASN ASN H . n 
A 1 31  THR 31  31  31  THR THR H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  SER 33  33  33  SER SER H . n 
A 1 34  MET 34  34  34  MET MET H . n 
A 1 35  ASN 35  35  35  ASN ASN H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  ALA 40  40  40  ALA ALA H . n 
A 1 41  PRO 41  41  41  PRO PRO H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  GLY 44  44  44  GLY GLY H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  TRP 47  47  47  TRP TRP H . n 
A 1 48  VAL 48  48  48  VAL VAL H . n 
A 1 49  SER 49  49  49  SER SER H . n 
A 1 50  SER 50  50  50  SER SER H . n 
A 1 51  ILE 51  51  51  ILE ILE H . n 
A 1 52  SER 52  52  52  SER SER H . n 
A 1 53  ARG 53  53  53  ARG ARG H . n 
A 1 54  SER 54  54  54  SER SER H . n 
A 1 55  SER 55  55  55  SER SER H . n 
A 1 56  ASP 56  56  56  ASP ASP H . n 
A 1 57  TYR 57  57  57  TYR TYR H . n 
A 1 58  ILE 58  58  58  ILE ILE H . n 
A 1 59  TYR 59  59  59  TYR TYR H . n 
A 1 60  TYR 60  60  60  TYR TYR H . n 
A 1 61  ALA 61  61  61  ALA ALA H . n 
A 1 62  ASP 62  62  62  ASP ASP H . n 
A 1 63  SER 63  63  63  SER SER H . n 
A 1 64  VAL 64  64  64  VAL VAL H . n 
A 1 65  LYS 65  65  65  LYS LYS H . n 
A 1 66  GLY 66  66  66  GLY GLY H . n 
A 1 67  ARG 67  67  67  ARG ARG H . n 
A 1 68  PHE 68  68  68  PHE PHE H . n 
A 1 69  THR 69  69  69  THR THR H . n 
A 1 70  ILE 70  70  70  ILE ILE H . n 
A 1 71  SER 71  71  71  SER SER H . n 
A 1 72  ARG 72  72  72  ARG ARG H . n 
A 1 73  ASP 73  73  73  ASP ASP H . n 
A 1 74  ASN 74  74  74  ASN ASN H . n 
A 1 75  ALA 75  75  75  ALA ALA H . n 
A 1 76  LYS 76  76  76  LYS LYS H . n 
A 1 77  ASN 77  77  77  ASN ASN H . n 
A 1 78  SER 78  78  78  SER SER H . n 
A 1 79  VAL 79  79  79  VAL VAL H . n 
A 1 80  TYR 80  80  80  TYR TYR H . n 
A 1 81  LEU 81  81  81  LEU LEU H . n 
A 1 82  GLN 82  82  82  GLN GLN H . n 
A 1 83  MET 83  83  83  MET MET H . n 
A 1 84  THR 84  84  84  THR THR H . n 
A 1 85  SER 85  85  85  SER SER H . n 
A 1 86  LEU 86  86  86  LEU LEU H . n 
A 1 87  ARG 87  87  87  ARG ARG H . n 
A 1 88  ASP 88  88  88  ASP ASP H . n 
A 1 89  GLU 89  89  89  GLU GLU H . n 
A 1 90  ASP 90  90  90  ASP ASP H . n 
A 1 91  THR 91  91  91  THR THR H . n 
A 1 92  ALA 92  92  92  ALA ALA H . n 
A 1 93  VAL 93  93  93  VAL VAL H . n 
A 1 94  TYR 94  94  94  TYR TYR H . n 
A 1 95  TYR 95  95  95  TYR TYR H . n 
A 1 96  CYS 96  96  96  CYS CYS H . n 
A 1 97  ALA 97  97  97  ALA ALA H . n 
A 1 98  ARG 98  98  98  ARG ARG H . n 
A 1 99  ASP 99  99  99  ASP ASP H . n 
A 1 100 PRO 100 100 100 PRO PRO H . n 
A 1 101 GLY 101 101 101 GLY GLY H . n 
A 1 102 GLY 102 102 102 GLY GLY H . n 
A 1 103 MET 103 103 103 MET MET H . n 
A 1 104 PRO 104 104 104 PRO PRO H . n 
A 1 105 THR 105 105 105 THR THR H . n 
A 1 106 THR 106 106 106 THR THR H . n 
A 1 107 VAL 107 107 107 VAL VAL H . n 
A 1 108 THR 108 108 108 THR THR H . n 
A 1 109 THR 109 109 109 THR THR H . n 
A 1 110 TRP 110 110 110 TRP TRP H . n 
A 1 111 LEU 111 111 111 LEU LEU H . n 
A 1 112 TYR 112 112 112 TYR TYR H . n 
A 1 113 TRP 113 113 113 TRP TRP H . n 
A 1 114 GLY 114 114 114 GLY GLY H . n 
A 1 115 GLN 115 115 115 GLN GLN H . n 
A 1 116 GLY 116 116 116 GLY GLY H . n 
A 1 117 THR 117 117 117 THR THR H . n 
A 1 118 LEU 118 118 118 LEU LEU H . n 
A 1 119 VAL 119 119 119 VAL VAL H . n 
A 1 120 THR 120 120 120 THR THR H . n 
A 1 121 VAL 121 121 121 VAL VAL H . n 
A 1 122 SER 122 122 122 SER SER H . n 
A 1 123 SER 123 123 123 SER SER H . n 
A 1 124 ALA 124 124 124 ALA ALA H . n 
A 1 125 SER 125 125 125 SER SER H . n 
A 1 126 THR 126 126 126 THR THR H . n 
A 1 127 LYS 127 127 127 LYS LYS H . n 
A 1 128 GLY 128 128 128 GLY GLY H . n 
A 1 129 PRO 129 129 129 PRO PRO H . n 
A 1 130 SER 130 130 130 SER SER H . n 
A 1 131 VAL 131 131 131 VAL VAL H . n 
A 1 132 PHE 132 132 132 PHE PHE H . n 
A 1 133 PRO 133 133 133 PRO PRO H . n 
A 1 134 LEU 134 134 134 LEU LEU H . n 
A 1 135 ALA 135 135 135 ALA ALA H . n 
A 1 136 PRO 136 136 136 PRO PRO H . n 
A 1 137 SER 137 137 137 SER SER H . n 
A 1 138 SER 138 138 138 SER SER H . n 
A 1 139 LYS 139 139 ?   ?   ?   H . n 
A 1 140 SER 140 140 ?   ?   ?   H . n 
A 1 141 THR 141 141 141 THR THR H . n 
A 1 142 SER 142 142 142 SER SER H . n 
A 1 143 GLY 143 143 143 GLY GLY H . n 
A 1 144 GLY 144 144 144 GLY GLY H . n 
A 1 145 THR 145 145 145 THR THR H . n 
A 1 146 ALA 146 146 146 ALA ALA H . n 
A 1 147 ALA 147 147 147 ALA ALA H . n 
A 1 148 LEU 148 148 148 LEU LEU H . n 
A 1 149 GLY 149 149 149 GLY GLY H . n 
A 1 150 CYS 150 150 150 CYS CYS H . n 
A 1 151 LEU 151 151 151 LEU LEU H . n 
A 1 152 VAL 152 152 152 VAL VAL H . n 
A 1 153 LYS 153 153 153 LYS LYS H . n 
A 1 154 ASP 154 154 154 ASP ASP H . n 
A 1 155 TYR 155 155 155 TYR TYR H . n 
A 1 156 PHE 156 156 156 PHE PHE H . n 
A 1 157 PRO 157 157 157 PRO PRO H . n 
A 1 158 GLU 158 158 158 GLU GLU H . n 
A 1 159 PRO 159 159 159 PRO PRO H . n 
A 1 160 VAL 160 160 160 VAL VAL H . n 
A 1 161 THR 161 161 161 THR THR H . n 
A 1 162 VAL 162 162 162 VAL VAL H . n 
A 1 163 SER 163 163 163 SER SER H . n 
A 1 164 TRP 164 164 164 TRP TRP H . n 
A 1 165 ASN 165 165 165 ASN ASN H . n 
A 1 166 SER 166 166 166 SER SER H . n 
A 1 167 GLY 167 167 167 GLY GLY H . n 
A 1 168 ALA 168 168 168 ALA ALA H . n 
A 1 169 LEU 169 169 169 LEU LEU H . n 
A 1 170 THR 170 170 170 THR THR H . n 
A 1 171 SER 171 171 171 SER SER H . n 
A 1 172 GLY 172 172 172 GLY GLY H . n 
A 1 173 VAL 173 173 173 VAL VAL H . n 
A 1 174 HIS 174 174 174 HIS HIS H . n 
A 1 175 THR 175 175 175 THR THR H . n 
A 1 176 PHE 176 176 176 PHE PHE H . n 
A 1 177 PRO 177 177 177 PRO PRO H . n 
A 1 178 ALA 178 178 178 ALA ALA H . n 
A 1 179 VAL 179 179 179 VAL VAL H . n 
A 1 180 LEU 180 180 180 LEU LEU H . n 
A 1 181 GLN 181 181 181 GLN GLN H . n 
A 1 182 SER 182 182 182 SER SER H . n 
A 1 183 SER 183 183 183 SER SER H . n 
A 1 184 GLY 184 184 184 GLY GLY H . n 
A 1 185 LEU 185 185 185 LEU LEU H . n 
A 1 186 TYR 186 186 186 TYR TYR H . n 
A 1 187 SER 187 187 187 SER SER H . n 
A 1 188 LEU 188 188 188 LEU LEU H . n 
A 1 189 SER 189 189 189 SER SER H . n 
A 1 190 SER 190 190 190 SER SER H . n 
A 1 191 VAL 191 191 191 VAL VAL H . n 
A 1 192 VAL 192 192 192 VAL VAL H . n 
A 1 193 THR 193 193 193 THR THR H . n 
A 1 194 VAL 194 194 194 VAL VAL H . n 
A 1 195 PRO 195 195 195 PRO PRO H . n 
A 1 196 SER 196 196 196 SER SER H . n 
A 1 197 SER 197 197 197 SER SER H . n 
A 1 198 SER 198 198 198 SER SER H . n 
A 1 199 LEU 199 199 199 LEU LEU H . n 
A 1 200 GLY 200 200 200 GLY GLY H . n 
A 1 201 THR 201 201 201 THR THR H . n 
A 1 202 GLN 202 202 202 GLN GLN H . n 
A 1 203 THR 203 203 203 THR THR H . n 
A 1 204 TYR 204 204 204 TYR TYR H . n 
A 1 205 ILE 205 205 205 ILE ILE H . n 
A 1 206 CYS 206 206 206 CYS CYS H . n 
A 1 207 ASN 207 207 207 ASN ASN H . n 
A 1 208 VAL 208 208 208 VAL VAL H . n 
A 1 209 ASN 209 209 209 ASN ASN H . n 
A 1 210 HIS 210 210 210 HIS HIS H . n 
A 1 211 LYS 211 211 211 LYS LYS H . n 
A 1 212 PRO 212 212 212 PRO PRO H . n 
A 1 213 SER 213 213 213 SER SER H . n 
A 1 214 ASN 214 214 214 ASN ASN H . n 
A 1 215 THR 215 215 215 THR THR H . n 
A 1 216 LYS 216 216 216 LYS LYS H . n 
A 1 217 VAL 217 217 217 VAL VAL H . n 
A 1 218 ASP 218 218 218 ASP ASP H . n 
A 1 219 LYS 219 219 219 LYS LYS H . n 
A 1 220 ARG 220 220 220 ARG ARG H . n 
A 1 221 VAL 221 221 221 VAL VAL H . n 
A 1 222 GLU 222 222 222 GLU GLU H . n 
A 1 223 PRO 223 223 223 PRO PRO H . n 
A 1 224 LYS 224 224 224 LYS LYS H . n 
B 2 1   GLU 1   1   1   GLU GLU L . n 
B 2 2   ILE 2   2   2   ILE ILE L . n 
B 2 3   VAL 3   3   3   VAL VAL L . n 
B 2 4   LEU 4   4   4   LEU LEU L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   GLY 9   9   9   GLY GLY L . n 
B 2 10  THR 10  10  10  THR THR L . n 
B 2 11  LEU 11  11  11  LEU LEU L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  LEU 13  13  13  LEU LEU L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  PRO 15  15  15  PRO PRO L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  GLU 17  17  17  GLU GLU L . n 
B 2 18  ARG 18  18  18  ARG ARG L . n 
B 2 19  ALA 19  19  19  ALA ALA L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  LEU 21  21  21  LEU LEU L . n 
B 2 22  SER 22  22  22  SER SER L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  GLN 27  27  27  GLN GLN L . n 
B 2 28  SER 28  28  28  SER SER L . n 
B 2 29  VAL 29  29  29  VAL VAL L . n 
B 2 30  THR 30  30  30  THR THR L . n 
B 2 31  SER 31  31  31  SER SER L . n 
B 2 32  ASN 32  32  32  ASN ASN L . n 
B 2 33  TYR 33  33  33  TYR TYR L . n 
B 2 34  LEU 34  34  34  LEU LEU L . n 
B 2 35  ALA 35  35  35  ALA ALA L . n 
B 2 36  TRP 36  36  36  TRP TRP L . n 
B 2 37  TYR 37  37  37  TYR TYR L . n 
B 2 38  GLN 38  38  38  GLN GLN L . n 
B 2 39  GLN 39  39  39  GLN GLN L . n 
B 2 40  LYS 40  40  40  LYS LYS L . n 
B 2 41  PRO 41  41  41  PRO PRO L . n 
B 2 42  GLY 42  42  42  GLY GLY L . n 
B 2 43  GLN 43  43  43  GLN GLN L . n 
B 2 44  ALA 44  44  44  ALA ALA L . n 
B 2 45  PRO 45  45  45  PRO PRO L . n 
B 2 46  ARG 46  46  46  ARG ARG L . n 
B 2 47  LEU 47  47  47  LEU LEU L . n 
B 2 48  LEU 48  48  48  LEU LEU L . n 
B 2 49  ILE 49  49  49  ILE ILE L . n 
B 2 50  TYR 50  50  50  TYR TYR L . n 
B 2 51  ASP 51  51  51  ASP ASP L . n 
B 2 52  THR 52  52  52  THR THR L . n 
B 2 53  SER 53  53  53  SER SER L . n 
B 2 54  ARG 54  54  54  ARG ARG L . n 
B 2 55  ARG 55  55  55  ARG ARG L . n 
B 2 56  ALA 56  56  56  ALA ALA L . n 
B 2 57  THR 57  57  57  THR THR L . n 
B 2 58  GLY 58  58  58  GLY GLY L . n 
B 2 59  ILE 59  59  59  ILE ILE L . n 
B 2 60  PRO 60  60  60  PRO PRO L . n 
B 2 61  ASP 61  61  61  ASP ASP L . n 
B 2 62  ARG 62  62  62  ARG ARG L . n 
B 2 63  PHE 63  63  63  PHE PHE L . n 
B 2 64  SER 64  64  64  SER SER L . n 
B 2 65  GLY 65  65  65  GLY GLY L . n 
B 2 66  SER 66  66  66  SER SER L . n 
B 2 67  GLY 67  67  67  GLY GLY L . n 
B 2 68  SER 68  68  68  SER SER L . n 
B 2 69  ALA 69  69  69  ALA ALA L . n 
B 2 70  THR 70  70  70  THR THR L . n 
B 2 71  ASP 71  71  71  ASP ASP L . n 
B 2 72  PHE 72  72  72  PHE PHE L . n 
B 2 73  THR 73  73  73  THR THR L . n 
B 2 74  LEU 74  74  74  LEU LEU L . n 
B 2 75  THR 75  75  75  THR THR L . n 
B 2 76  ILE 76  76  76  ILE ILE L . n 
B 2 77  SER 77  77  77  SER SER L . n 
B 2 78  ARG 78  78  78  ARG ARG L . n 
B 2 79  LEU 79  79  79  LEU LEU L . n 
B 2 80  GLU 80  80  80  GLU GLU L . n 
B 2 81  PRO 81  81  81  PRO PRO L . n 
B 2 82  ASP 82  82  82  ASP ASP L . n 
B 2 83  ASP 83  83  83  ASP ASP L . n 
B 2 84  PHE 84  84  84  PHE PHE L . n 
B 2 85  ALA 85  85  85  ALA ALA L . n 
B 2 86  ILE 86  86  86  ILE ILE L . n 
B 2 87  TYR 87  87  87  TYR TYR L . n 
B 2 88  TYR 88  88  88  TYR TYR L . n 
B 2 89  CYS 89  89  89  CYS CYS L . n 
B 2 90  GLN 90  90  90  GLN GLN L . n 
B 2 91  GLN 91  91  91  GLN GLN L . n 
B 2 92  TYR 92  92  92  TYR TYR L . n 
B 2 93  GLY 93  93  93  GLY GLY L . n 
B 2 94  SER 94  94  94  SER SER L . n 
B 2 95  SER 95  95  ?   ?   ?   L . n 
B 2 96  PRO 96  96  ?   ?   ?   L . n 
B 2 97  PRO 97  97  97  PRO PRO L . n 
B 2 98  VAL 98  98  98  VAL VAL L . n 
B 2 99  THR 99  99  99  THR THR L . n 
B 2 100 PHE 100 100 100 PHE PHE L . n 
B 2 101 GLY 101 101 101 GLY GLY L . n 
B 2 102 HIS 102 102 102 HIS HIS L . n 
B 2 103 GLY 103 103 103 GLY GLY L . n 
B 2 104 THR 104 104 104 THR THR L . n 
B 2 105 LYS 105 105 105 LYS LYS L . n 
B 2 106 VAL 106 106 106 VAL VAL L . n 
B 2 107 GLU 107 107 107 GLU GLU L . n 
B 2 108 ILE 108 108 108 ILE ILE L . n 
B 2 109 LYS 109 109 109 LYS LYS L . n 
B 2 110 ARG 110 110 110 ARG ARG L . n 
B 2 111 THR 111 111 111 THR THR L . n 
B 2 112 VAL 112 112 112 VAL VAL L . n 
B 2 113 ALA 113 113 113 ALA ALA L . n 
B 2 114 ALA 114 114 114 ALA ALA L . n 
B 2 115 PRO 115 115 115 PRO PRO L . n 
B 2 116 SER 116 116 116 SER SER L . n 
B 2 117 VAL 117 117 117 VAL VAL L . n 
B 2 118 PHE 118 118 118 PHE PHE L . n 
B 2 119 ILE 119 119 119 ILE ILE L . n 
B 2 120 PHE 120 120 120 PHE PHE L . n 
B 2 121 PRO 121 121 121 PRO PRO L . n 
B 2 122 PRO 122 122 122 PRO PRO L . n 
B 2 123 SER 123 123 123 SER SER L . n 
B 2 124 ASP 124 124 124 ASP ASP L . n 
B 2 125 GLU 125 125 125 GLU GLU L . n 
B 2 126 GLN 126 126 126 GLN GLN L . n 
B 2 127 LEU 127 127 127 LEU LEU L . n 
B 2 128 LYS 128 128 128 LYS LYS L . n 
B 2 129 SER 129 129 129 SER SER L . n 
B 2 130 GLY 130 130 130 GLY GLY L . n 
B 2 131 THR 131 131 131 THR THR L . n 
B 2 132 ALA 132 132 132 ALA ALA L . n 
B 2 133 SER 133 133 133 SER SER L . n 
B 2 134 VAL 134 134 134 VAL VAL L . n 
B 2 135 VAL 135 135 135 VAL VAL L . n 
B 2 136 CYS 136 136 136 CYS CYS L . n 
B 2 137 LEU 137 137 137 LEU LEU L . n 
B 2 138 LEU 138 138 138 LEU LEU L . n 
B 2 139 ASN 139 139 139 ASN ASN L . n 
B 2 140 ASN 140 140 140 ASN ASN L . n 
B 2 141 PHE 141 141 141 PHE PHE L . n 
B 2 142 TYR 142 142 142 TYR TYR L . n 
B 2 143 PRO 143 143 143 PRO PRO L . n 
B 2 144 ARG 144 144 144 ARG ARG L . n 
B 2 145 GLU 145 145 145 GLU GLU L . n 
B 2 146 ALA 146 146 146 ALA ALA L . n 
B 2 147 LYS 147 147 147 LYS LYS L . n 
B 2 148 VAL 148 148 148 VAL VAL L . n 
B 2 149 GLN 149 149 149 GLN GLN L . n 
B 2 150 TRP 150 150 150 TRP TRP L . n 
B 2 151 LYS 151 151 151 LYS LYS L . n 
B 2 152 VAL 152 152 152 VAL VAL L . n 
B 2 153 ASP 153 153 153 ASP ASP L . n 
B 2 154 ASN 154 154 154 ASN ASN L . n 
B 2 155 ALA 155 155 155 ALA ALA L . n 
B 2 156 LEU 156 156 156 LEU LEU L . n 
B 2 157 GLN 157 157 157 GLN GLN L . n 
B 2 158 SER 158 158 158 SER SER L . n 
B 2 159 GLY 159 159 159 GLY GLY L . n 
B 2 160 ASN 160 160 160 ASN ASN L . n 
B 2 161 SER 161 161 161 SER SER L . n 
B 2 162 GLN 162 162 162 GLN GLN L . n 
B 2 163 GLU 163 163 163 GLU GLU L . n 
B 2 164 SER 164 164 164 SER SER L . n 
B 2 165 VAL 165 165 165 VAL VAL L . n 
B 2 166 THR 166 166 166 THR THR L . n 
B 2 167 GLU 167 167 167 GLU GLU L . n 
B 2 168 GLN 168 168 168 GLN GLN L . n 
B 2 169 ASP 169 169 169 ASP ASP L . n 
B 2 170 SER 170 170 170 SER SER L . n 
B 2 171 LYS 171 171 171 LYS LYS L . n 
B 2 172 ASP 172 172 172 ASP ASP L . n 
B 2 173 SER 173 173 173 SER SER L . n 
B 2 174 THR 174 174 174 THR THR L . n 
B 2 175 TYR 175 175 175 TYR TYR L . n 
B 2 176 SER 176 176 176 SER SER L . n 
B 2 177 LEU 177 177 177 LEU LEU L . n 
B 2 178 SER 178 178 178 SER SER L . n 
B 2 179 SER 179 179 179 SER SER L . n 
B 2 180 THR 180 180 180 THR THR L . n 
B 2 181 LEU 181 181 181 LEU LEU L . n 
B 2 182 THR 182 182 182 THR THR L . n 
B 2 183 LEU 183 183 183 LEU LEU L . n 
B 2 184 SER 184 184 184 SER SER L . n 
B 2 185 LYS 185 185 185 LYS LYS L . n 
B 2 186 ALA 186 186 186 ALA ALA L . n 
B 2 187 ASP 187 187 187 ASP ASP L . n 
B 2 188 TYR 188 188 188 TYR TYR L . n 
B 2 189 GLU 189 189 189 GLU GLU L . n 
B 2 190 LYS 190 190 190 LYS LYS L . n 
B 2 191 HIS 191 191 191 HIS HIS L . n 
B 2 192 LYS 192 192 192 LYS LYS L . n 
B 2 193 VAL 193 193 193 VAL VAL L . n 
B 2 194 TYR 194 194 194 TYR TYR L . n 
B 2 195 ALA 195 195 195 ALA ALA L . n 
B 2 196 CYS 196 196 196 CYS CYS L . n 
B 2 197 GLU 197 197 197 GLU GLU L . n 
B 2 198 VAL 198 198 198 VAL VAL L . n 
B 2 199 THR 199 199 199 THR THR L . n 
B 2 200 HIS 200 200 200 HIS HIS L . n 
B 2 201 GLN 201 201 201 GLN GLN L . n 
B 2 202 GLY 202 202 202 GLY GLY L . n 
B 2 203 LEU 203 203 203 LEU LEU L . n 
B 2 204 SER 204 204 204 SER SER L . n 
B 2 205 SER 205 205 205 SER SER L . n 
B 2 206 PRO 206 206 206 PRO PRO L . n 
B 2 207 VAL 207 207 207 VAL VAL L . n 
B 2 208 THR 208 208 208 THR THR L . n 
B 2 209 LYS 209 209 209 LYS LYS L . n 
B 2 210 SER 210 210 210 SER SER L . n 
B 2 211 PHE 211 211 211 PHE PHE L . n 
B 2 212 ASN 212 212 212 ASN ASN L . n 
B 2 213 ARG 213 213 213 ARG ARG L . n 
B 2 214 GLY 214 214 214 GLY GLY L . n 
B 2 215 GLU 215 215 215 GLU GLU L . n 
B 2 216 CYS 216 216 ?   ?   ?   L . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 A1H09 1  301 301 A1H09 DPT H . 
D 4 ZN    1  301 1   ZN    ZN  L . 
E 5 HOH   1  401 28  HOH   HOH H . 
E 5 HOH   2  402 14  HOH   HOH H . 
E 5 HOH   3  403 38  HOH   HOH H . 
E 5 HOH   4  404 29  HOH   HOH H . 
E 5 HOH   5  405 9   HOH   HOH H . 
E 5 HOH   6  406 1   HOH   HOH H . 
E 5 HOH   7  407 19  HOH   HOH H . 
E 5 HOH   8  408 23  HOH   HOH H . 
E 5 HOH   9  409 12  HOH   HOH H . 
E 5 HOH   10 410 7   HOH   HOH H . 
E 5 HOH   11 411 25  HOH   HOH H . 
E 5 HOH   12 412 42  HOH   HOH H . 
E 5 HOH   13 413 24  HOH   HOH H . 
E 5 HOH   14 414 11  HOH   HOH H . 
E 5 HOH   15 415 6   HOH   HOH H . 
E 5 HOH   16 416 13  HOH   HOH H . 
E 5 HOH   17 417 33  HOH   HOH H . 
E 5 HOH   18 418 35  HOH   HOH H . 
E 5 HOH   19 419 52  HOH   HOH H . 
E 5 HOH   20 420 37  HOH   HOH H . 
E 5 HOH   21 421 46  HOH   HOH H . 
E 5 HOH   22 422 50  HOH   HOH H . 
E 5 HOH   23 423 31  HOH   HOH H . 
E 5 HOH   24 424 49  HOH   HOH H . 
E 5 HOH   25 425 21  HOH   HOH H . 
F 5 HOH   1  401 8   HOH   HOH L . 
F 5 HOH   2  402 10  HOH   HOH L . 
F 5 HOH   3  403 17  HOH   HOH L . 
F 5 HOH   4  404 36  HOH   HOH L . 
F 5 HOH   5  405 15  HOH   HOH L . 
F 5 HOH   6  406 40  HOH   HOH L . 
F 5 HOH   7  407 4   HOH   HOH L . 
F 5 HOH   8  408 22  HOH   HOH L . 
F 5 HOH   9  409 16  HOH   HOH L . 
F 5 HOH   10 410 56  HOH   HOH L . 
F 5 HOH   11 411 3   HOH   HOH L . 
F 5 HOH   12 412 27  HOH   HOH L . 
F 5 HOH   13 413 5   HOH   HOH L . 
F 5 HOH   14 414 20  HOH   HOH L . 
F 5 HOH   15 415 39  HOH   HOH L . 
F 5 HOH   16 416 44  HOH   HOH L . 
F 5 HOH   17 417 47  HOH   HOH L . 
F 5 HOH   18 418 26  HOH   HOH L . 
F 5 HOH   19 419 41  HOH   HOH L . 
F 5 HOH   20 420 32  HOH   HOH L . 
F 5 HOH   21 421 34  HOH   HOH L . 
F 5 HOH   22 422 18  HOH   HOH L . 
F 5 HOH   23 423 51  HOH   HOH L . 
F 5 HOH   24 424 53  HOH   HOH L . 
F 5 HOH   25 425 48  HOH   HOH L . 
F 5 HOH   26 426 59  HOH   HOH L . 
F 5 HOH   27 427 57  HOH   HOH L . 
F 5 HOH   28 428 45  HOH   HOH L . 
F 5 HOH   29 429 43  HOH   HOH L . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 H GLN   115 ? CG  ? A GLN   115 CG  
2  1 Y 1 H GLN   115 ? CD  ? A GLN   115 CD  
3  1 Y 1 H GLN   115 ? OE1 ? A GLN   115 OE1 
4  1 Y 1 H GLN   115 ? NE2 ? A GLN   115 NE2 
5  1 Y 1 H LYS   224 ? CG  ? A LYS   224 CG  
6  1 Y 1 H LYS   224 ? CD  ? A LYS   224 CD  
7  1 Y 1 H LYS   224 ? CE  ? A LYS   224 CE  
8  1 Y 1 H LYS   224 ? NZ  ? A LYS   224 NZ  
9  1 Y 1 L PHE   84  ? CG  ? B PHE   84  CG  
10 1 Y 1 L PHE   84  ? CD1 ? B PHE   84  CD1 
11 1 Y 1 L PHE   84  ? CD2 ? B PHE   84  CD2 
12 1 Y 1 L PHE   84  ? CE1 ? B PHE   84  CE1 
13 1 Y 1 L PHE   84  ? CE2 ? B PHE   84  CE2 
14 1 Y 1 L PHE   84  ? CZ  ? B PHE   84  CZ  
15 1 Y 1 L LYS   171 ? CG  ? B LYS   171 CG  
16 1 Y 1 L LYS   171 ? CD  ? B LYS   171 CD  
17 1 Y 1 L LYS   171 ? CE  ? B LYS   171 CE  
18 1 Y 1 L LYS   171 ? NZ  ? B LYS   171 NZ  
19 1 Y 1 L LYS   190 ? CG  ? B LYS   190 CG  
20 1 Y 1 L LYS   190 ? CD  ? B LYS   190 CD  
21 1 Y 1 L LYS   190 ? CE  ? B LYS   190 CE  
22 1 Y 1 L LYS   190 ? NZ  ? B LYS   190 NZ  
23 1 Y 1 L GLU   215 ? CG  ? B GLU   215 CG  
24 1 Y 1 L GLU   215 ? CD  ? B GLU   215 CD  
25 1 Y 1 L GLU   215 ? OE1 ? B GLU   215 OE1 
26 1 Y 1 L GLU   215 ? OE2 ? B GLU   215 OE2 
27 1 N 0 H A1H09 301 ? C15 ? C A1H09 ?   C15 
28 1 N 0 H A1H09 301 ? O16 ? C A1H09 ?   O16 
29 1 N 0 H A1H09 301 ? C16 ? C A1H09 ?   C16 
30 1 N 0 H A1H09 301 ? O17 ? C A1H09 ?   O17 
31 1 N 0 H A1H09 301 ? C8  ? C A1H09 ?   C8  
32 1 N 0 H A1H09 301 ? O18 ? C A1H09 ?   O18 
33 1 N 0 H A1H09 301 ? C17 ? C A1H09 ?   C17 
34 1 N 0 H A1H09 301 ? O19 ? C A1H09 ?   O19 
35 1 N 0 H A1H09 301 ? C18 ? C A1H09 ?   C18 
36 1 N 0 H A1H09 301 ? O20 ? C A1H09 ?   O20 
37 1 N 0 H A1H09 301 ? P2  ? C A1H09 ?   P2  
38 1 N 0 H A1H09 301 ? O8  ? C A1H09 ?   O8  
39 1 N 0 H A1H09 301 ? O9  ? C A1H09 ?   O9  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.15.2_3472 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS   ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8RDF 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     60.928 
_cell.length_a_esd                 ? 
_cell.length_b                     131.288 
_cell.length_b_esd                 ? 
_cell.length_c                     144.964 
_cell.length_c_esd                 ? 
_cell.volume                       1159578.036 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8RDF 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8RDF 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.08 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.08 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.01M Nickel(II) chloride hexahydrate, 0.1M Tris pH 8.5, 20% w/v PEG 2000 MME' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 2M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-10-13 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.965 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE MASSIF-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.965 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MASSIF-1 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          44.02 
_reflns.entry_id                                       8RDF 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.74 
_reflns.d_resolution_low                               65.64 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     15060 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           96.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.94 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.18 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.74 
_reflns_shell.d_res_low                                     2.87 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.2 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2007 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.58 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.94 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               43.62 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8RDF 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.74 
_refine.ls_d_res_low                             65.64 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     14988 
_refine.ls_number_reflns_R_free                  757 
_refine.ls_number_reflns_R_work                  14231 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.52 
_refine.ls_percent_reflns_R_free                 5.05 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2284 
_refine.ls_R_factor_R_free                       0.2770 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2259 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.6081 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3567 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.74 
_refine_hist.d_res_low                        65.64 
_refine_hist.number_atoms_solvent             54 
_refine_hist.number_atoms_total               3404 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3282 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         68 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0032  ? 3425 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.6902  ? 4675 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0476  ? 548  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0048  ? 585  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 20.5995 ? 1248 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.74 2.95  . . 162 2835 97.56 . . . . 0.3272 . . . . . . . . . . . 0.3597 
'X-RAY DIFFRACTION' 2.95 3.25  . . 174 2833 97.03 . . . . 0.2797 . . . . . . . . . . . 0.3491 
'X-RAY DIFFRACTION' 3.25 3.72  . . 143 2816 95.36 . . . . 0.2386 . . . . . . . . . . . 0.2802 
'X-RAY DIFFRACTION' 3.72 4.68  . . 148 2862 95.56 . . . . 0.1875 . . . . . . . . . . . 0.2527 
'X-RAY DIFFRACTION' 4.68 65.64 . . 130 2885 92.31 . . . . 0.1971 . . . . . . . . . . . 0.2227 
# 
_struct.entry_id                     8RDF 
_struct.title                        
'Crystal structure of Haemophilus influenzae type b (Hib) DP3 oligosaccharide bound to Fab CA4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8RDF 
_struct_keywords.text            'antigen, antibody, carbohydrate, Haemophilus influenzae type b, Hib, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8RDF 8RDF ? 1 ? 1 
2 PDB 8RDF 8RDF ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8RDF H 1 ? 224 ? 8RDF 1 ? 224 ? 1 224 
2 2 8RDF L 1 ? 216 ? 8RDF 1 ? 216 ? 1 216 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3250  ? 
1 MORE         -42   ? 
1 'SSA (A^2)'  19380 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR A 28  ? TYR A 32  ? THR H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2 AA2 ARG A 87  ? THR A 91  ? ARG H 87  THR H 91  5 ? 5 
HELX_P HELX_P3 AA3 SER A 197 ? GLN A 202 ? SER H 197 GLN H 202 1 ? 6 
HELX_P HELX_P4 AA4 LYS A 211 ? ASN A 214 ? LYS H 211 ASN H 214 5 ? 4 
HELX_P HELX_P5 AA5 VAL B 29  ? ASN B 32  ? VAL L 29  ASN L 32  5 ? 4 
HELX_P HELX_P6 AA6 GLU B 80  ? PHE B 84  ? GLU L 80  PHE L 84  5 ? 5 
HELX_P HELX_P7 AA7 ASP B 124 ? GLY B 130 ? ASP L 124 GLY L 130 1 ? 7 
HELX_P HELX_P8 AA8 LYS B 185 ? LYS B 190 ? LYS L 185 LYS L 190 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22  SG ? ? ? 1_555 A CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf2 disulf ? ? A CYS 150 SG ? ? ? 1_555 A CYS 206 SG ? ? H CYS 150 H CYS 206 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf3 disulf ? ? B CYS 23  SG ? ? ? 1_555 B CYS 89  SG ? ? L CYS 23  L CYS 89  1_555 ? ? ? ? ? ? ? 2.037 ? ? 
disulf4 disulf ? ? B CYS 136 SG ? ? ? 1_555 B CYS 196 SG ? ? L CYS 136 L CYS 196 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 156 A . ? PHE 156 H PRO 157 A ? PRO 157 H 1 -4.69 
2 GLU 158 A . ? GLU 158 H PRO 159 A ? PRO 159 H 1 -3.70 
3 SER 7   B . ? SER 7   L PRO 8   B ? PRO 8   L 1 -3.18 
4 TYR 142 B . ? TYR 142 L PRO 143 B ? PRO 143 L 1 5.03  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? SER A 7   ? GLN H 3   SER H 7   
AA1 2 LEU A 18  ? SER A 25  ? LEU H 18  SER H 25  
AA1 3 SER A 78  ? MET A 83  ? SER H 78  MET H 83  
AA1 4 PHE A 68  ? ASP A 73  ? PHE H 68  ASP H 73  
AA2 1 GLY A 10  ? VAL A 12  ? GLY H 10  VAL H 12  
AA2 2 THR A 117 ? VAL A 121 ? THR H 117 VAL H 121 
AA2 3 ALA A 92  ? ARG A 98  ? ALA H 92  ARG H 98  
AA2 4 MET A 34  ? GLN A 39  ? MET H 34  GLN H 39  
AA2 5 LEU A 45  ? ILE A 51  ? LEU H 45  ILE H 51  
AA2 6 ILE A 58  ? TYR A 60  ? ILE H 58  TYR H 60  
AA3 1 GLY A 10  ? VAL A 12  ? GLY H 10  VAL H 12  
AA3 2 THR A 117 ? VAL A 121 ? THR H 117 VAL H 121 
AA3 3 ALA A 92  ? ARG A 98  ? ALA H 92  ARG H 98  
AA3 4 TYR A 112 ? TRP A 113 ? TYR H 112 TRP H 113 
AA4 1 SER A 130 ? LEU A 134 ? SER H 130 LEU H 134 
AA4 2 THR A 145 ? TYR A 155 ? THR H 145 TYR H 155 
AA4 3 TYR A 186 ? PRO A 195 ? TYR H 186 PRO H 195 
AA4 4 VAL A 173 ? THR A 175 ? VAL H 173 THR H 175 
AA5 1 SER A 130 ? LEU A 134 ? SER H 130 LEU H 134 
AA5 2 THR A 145 ? TYR A 155 ? THR H 145 TYR H 155 
AA5 3 TYR A 186 ? PRO A 195 ? TYR H 186 PRO H 195 
AA5 4 VAL A 179 ? LEU A 180 ? VAL H 179 LEU H 180 
AA6 1 THR A 161 ? TRP A 164 ? THR H 161 TRP H 164 
AA6 2 TYR A 204 ? HIS A 210 ? TYR H 204 HIS H 210 
AA6 3 THR A 215 ? VAL A 221 ? THR H 215 VAL H 221 
AA7 1 LEU B 4   ? SER B 7   ? LEU L 4   SER L 7   
AA7 2 ALA B 19  ? ALA B 25  ? ALA L 19  ALA L 25  
AA7 3 ASP B 71  ? ILE B 76  ? ASP L 71  ILE L 76  
AA7 4 PHE B 63  ? SER B 68  ? PHE L 63  SER L 68  
AA8 1 THR B 10  ? LEU B 13  ? THR L 10  LEU L 13  
AA8 2 THR B 104 ? ILE B 108 ? THR L 104 ILE L 108 
AA8 3 ALA B 85  ? GLN B 91  ? ALA L 85  GLN L 91  
AA8 4 LEU B 34  ? GLN B 39  ? LEU L 34  GLN L 39  
AA8 5 ARG B 46  ? TYR B 50  ? ARG L 46  TYR L 50  
AA8 6 ARG B 54  ? ARG B 55  ? ARG L 54  ARG L 55  
AA9 1 THR B 10  ? LEU B 13  ? THR L 10  LEU L 13  
AA9 2 THR B 104 ? ILE B 108 ? THR L 104 ILE L 108 
AA9 3 ALA B 85  ? GLN B 91  ? ALA L 85  GLN L 91  
AA9 4 THR B 99  ? PHE B 100 ? THR L 99  PHE L 100 
AB1 1 SER B 116 ? PHE B 120 ? SER L 116 PHE L 120 
AB1 2 THR B 131 ? PHE B 141 ? THR L 131 PHE L 141 
AB1 3 TYR B 175 ? SER B 184 ? TYR L 175 SER L 184 
AB1 4 SER B 161 ? VAL B 165 ? SER L 161 VAL L 165 
AB2 1 ALA B 155 ? LEU B 156 ? ALA L 155 LEU L 156 
AB2 2 ALA B 146 ? VAL B 152 ? ALA L 146 VAL L 152 
AB2 3 VAL B 193 ? HIS B 200 ? VAL L 193 HIS L 200 
AB2 4 VAL B 207 ? ASN B 212 ? VAL L 207 ASN L 212 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O SER A 21  ? O SER H 21  
AA1 2 3 N LEU A 18  ? N LEU H 18  O MET A 83  ? O MET H 83  
AA1 3 4 O TYR A 80  ? O TYR H 80  N SER A 71  ? N SER H 71  
AA2 1 2 N VAL A 12  ? N VAL H 12  O THR A 120 ? O THR H 120 
AA2 2 3 O THR A 117 ? O THR H 117 N TYR A 94  ? N TYR H 94  
AA2 3 4 O TYR A 95  ? O TYR H 95  N VAL A 37  ? N VAL H 37  
AA2 4 5 N TRP A 36  ? N TRP H 36  O SER A 49  ? O SER H 49  
AA2 5 6 N SER A 50  ? N SER H 50  O TYR A 59  ? O TYR H 59  
AA3 1 2 N VAL A 12  ? N VAL H 12  O THR A 120 ? O THR H 120 
AA3 2 3 O THR A 117 ? O THR H 117 N TYR A 94  ? N TYR H 94  
AA3 3 4 N ARG A 98  ? N ARG H 98  O TYR A 112 ? O TYR H 112 
AA4 1 2 N PHE A 132 ? N PHE H 132 O LEU A 151 ? O LEU H 151 
AA4 2 3 N ALA A 146 ? N ALA H 146 O VAL A 194 ? O VAL H 194 
AA4 3 4 O VAL A 191 ? O VAL H 191 N HIS A 174 ? N HIS H 174 
AA5 1 2 N PHE A 132 ? N PHE H 132 O LEU A 151 ? O LEU H 151 
AA5 2 3 N ALA A 146 ? N ALA H 146 O VAL A 194 ? O VAL H 194 
AA5 3 4 O SER A 187 ? O SER H 187 N VAL A 179 ? N VAL H 179 
AA6 1 2 N SER A 163 ? N SER H 163 O ASN A 207 ? O ASN H 207 
AA6 2 3 N VAL A 208 ? N VAL H 208 O VAL A 217 ? O VAL H 217 
AA7 1 2 N THR B 5   ? N THR L 5   O ARG B 24  ? O ARG L 24  
AA7 2 3 N LEU B 21  ? N LEU L 21  O LEU B 74  ? O LEU L 74  
AA7 3 4 O THR B 75  ? O THR L 75  N SER B 64  ? N SER L 64  
AA8 1 2 N LEU B 11  ? N LEU L 11  O GLU B 107 ? O GLU L 107 
AA8 2 3 O VAL B 106 ? O VAL L 106 N ALA B 85  ? N ALA L 85  
AA8 3 4 O TYR B 88  ? O TYR L 88  N TYR B 37  ? N TYR L 37  
AA8 4 5 N GLN B 38  ? N GLN L 38  O ARG B 46  ? O ARG L 46  
AA8 5 6 N TYR B 50  ? N TYR L 50  O ARG B 54  ? O ARG L 54  
AA9 1 2 N LEU B 11  ? N LEU L 11  O GLU B 107 ? O GLU L 107 
AA9 2 3 O VAL B 106 ? O VAL L 106 N ALA B 85  ? N ALA L 85  
AA9 3 4 N GLN B 91  ? N GLN L 91  O THR B 99  ? O THR L 99  
AB1 1 2 N PHE B 118 ? N PHE L 118 O LEU B 137 ? O LEU L 137 
AB1 2 3 N VAL B 134 ? N VAL L 134 O LEU B 181 ? O LEU L 181 
AB1 3 4 O SER B 178 ? O SER L 178 N SER B 164 ? N SER L 164 
AB2 1 2 O ALA B 155 ? O ALA L 155 N VAL B 152 ? N VAL L 152 
AB2 2 3 N GLN B 149 ? N GLN L 149 O GLU B 197 ? O GLU L 197 
AB2 3 4 N VAL B 198 ? N VAL L 198 O VAL B 207 ? O VAL L 207 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   L 
_pdbx_validate_close_contact.auth_comp_id_1   TYR 
_pdbx_validate_close_contact.auth_seq_id_1    188 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OH 
_pdbx_validate_close_contact.auth_asym_id_2   L 
_pdbx_validate_close_contact.auth_comp_id_2   TYR 
_pdbx_validate_close_contact.auth_seq_id_2    194 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.07 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    H 
_pdbx_validate_symm_contact.auth_comp_id_1    LYS 
_pdbx_validate_symm_contact.auth_seq_id_1     76 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    OG 
_pdbx_validate_symm_contact.auth_asym_id_2    H 
_pdbx_validate_symm_contact.auth_comp_id_2    SER 
_pdbx_validate_symm_contact.auth_seq_id_2     197 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   4_555 
_pdbx_validate_symm_contact.dist              2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER H 55  ? ? 58.87   17.75   
2  1 PRO H 100 ? ? -66.98  2.46    
3  1 THR H 108 ? ? -143.74 -114.53 
4  1 SER H 122 ? ? -171.57 144.03  
5  1 SER H 137 ? ? -76.24  -143.57 
6  1 ASP H 154 ? ? 60.16   92.52   
7  1 SER H 166 ? ? 36.06   64.95   
8  1 THR H 170 ? ? -132.85 -34.54  
9  1 SER L 31  ? ? 59.44   19.27   
10 1 THR L 52  ? ? 67.23   -45.51  
11 1 ALA L 69  ? ? 62.47   -91.92  
12 1 TYR L 92  ? ? -145.96 44.86   
13 1 ASN L 140 ? ? 47.78   86.58   
14 1 LYS L 192 ? ? -128.93 -52.53  
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    H 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     424 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   E 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
_pdbx_entry_details.entry_id                   8RDF 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   ? 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 H LYS 139 ? A LYS 139 
2 1 Y 1 H SER 140 ? A SER 140 
3 1 Y 1 L SER 95  ? B SER 95  
4 1 Y 1 L PRO 96  ? B PRO 96  
5 1 Y 1 L CYS 216 ? B CYS 216 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1H09 C15  C  N R 1   
A1H09 O16  O  N N 2   
A1H09 C16  C  N R 3   
A1H09 O17  O  N N 4   
A1H09 C8   C  N R 5   
A1H09 O18  O  N N 6   
A1H09 C17  C  N S 7   
A1H09 O19  O  N N 8   
A1H09 C18  C  N N 9   
A1H09 O20  O  N N 10  
A1H09 O12  O  N N 11  
A1H09 C13  C  N N 12  
A1H09 O23  O  N N 13  
A1H09 C33  C  N S 14  
A1H09 O33  O  N N 15  
A1H09 C43  C  N R 16  
A1H09 O43  O  N N 17  
A1H09 C53  C  N N 18  
A1H09 C23  C  N S 19  
A1H09 O53  O  N N 20  
A1H09 P2   P  N N 21  
A1H09 O8   O  N N 22  
A1H09 O9   O  N N 23  
A1H09 C9   C  N R 24  
A1H09 O10  O  N N 25  
A1H09 C6   C  N R 26  
A1H09 C7   C  N R 27  
A1H09 O13  O  N N 28  
A1H09 C10  C  N S 29  
A1H09 O14  O  N N 30  
A1H09 C14  C  N N 31  
A1H09 O15  O  N N 32  
A1H09 O11  O  N N 33  
A1H09 C11  C  N N 34  
A1H09 O21  O  N N 35  
A1H09 C31  C  N S 36  
A1H09 O31  O  N N 37  
A1H09 C41  C  N R 38  
A1H09 O41  O  N N 39  
A1H09 C51  C  N N 40  
A1H09 C21  C  N S 41  
A1H09 O51  O  N N 42  
A1H09 P1   P  N N 43  
A1H09 O6   O  N N 44  
A1H09 O7   O  N N 45  
A1H09 C42  C  N R 46  
A1H09 O42  O  N N 47  
A1H09 C12  C  N R 48  
A1H09 C22  C  N R 49  
A1H09 O22  O  N N 50  
A1H09 C32  C  N S 51  
A1H09 O32  O  N N 52  
A1H09 C52  C  N N 53  
A1H09 O52  O  N N 54  
A1H09 O1   O  N N 55  
A1H09 C1   C  N N 56  
A1H09 O2   O  N N 57  
A1H09 C3   C  N S 58  
A1H09 O3   O  N N 59  
A1H09 C4   C  N R 60  
A1H09 O4   O  N N 61  
A1H09 C5   C  N N 62  
A1H09 C2   C  N S 63  
A1H09 O5   O  N N 64  
A1H09 P    P  N N 65  
A1H09 O2P  O  N N 66  
A1H09 O1P  O  N N 67  
A1H09 H15  H  N N 68  
A1H09 H16  H  N N 69  
A1H09 H57  H  N N 70  
A1H09 H49  H  N N 71  
A1H09 H58  H  N N 72  
A1H09 H17  H  N N 73  
A1H09 H18  H  N N 74  
A1H09 H19  H  N N 75  
A1H09 H59  H  N N 76  
A1H09 H42  H  N N 77  
A1H09 H41  H  N N 78  
A1H09 H50  H  N N 79  
A1H09 H44  H  N N 80  
A1H09 H51  H  N N 81  
A1H09 H45  H  N N 82  
A1H09 H52  H  N N 83  
A1H09 H46  H  N N 84  
A1H09 H47  H  N N 85  
A1H09 H43  H  N N 86  
A1H09 H10  H  N N 87  
A1H09 H11  H  N N 88  
A1H09 H48  H  N N 89  
A1H09 H9   H  N N 90  
A1H09 H14  H  N N 91  
A1H09 H53  H  N N 92  
A1H09 H54  H  N N 93  
A1H09 H55  H  N N 94  
A1H09 H56  H  N N 95  
A1H09 H13  H  N N 96  
A1H09 H12  H  N N 97  
A1H09 H27  H  N N 98  
A1H09 H28  H  N N 99  
A1H09 H29  H  N N 100 
A1H09 H30  H  N N 101 
A1H09 H31  H  N N 102 
A1H09 H32  H  N N 103 
A1H09 H33  H  N N 104 
A1H09 H20  H  N N 105 
A1H09 H8   H  N N 106 
A1H09 H34  H  N N 107 
A1H09 H35  H  N N 108 
A1H09 H21  H  N N 109 
A1H09 H36  H  N N 110 
A1H09 H37  H  N N 111 
A1H09 H38  H  N N 112 
A1H09 H39  H  N N 113 
A1H09 H40  H  N N 114 
A1H09 H22  H  N N 115 
A1H09 H2   H  N N 116 
A1H09 H1   H  N N 117 
A1H09 H23  H  N N 118 
A1H09 H4   H  N N 119 
A1H09 H24  H  N N 120 
A1H09 H5   H  N N 121 
A1H09 H25  H  N N 122 
A1H09 H6   H  N N 123 
A1H09 H7   H  N N 124 
A1H09 H3   H  N N 125 
A1H09 H26  H  N N 126 
ALA   N    N  N N 127 
ALA   CA   C  N S 128 
ALA   C    C  N N 129 
ALA   O    O  N N 130 
ALA   CB   C  N N 131 
ALA   OXT  O  N N 132 
ALA   H    H  N N 133 
ALA   H2   H  N N 134 
ALA   HA   H  N N 135 
ALA   HB1  H  N N 136 
ALA   HB2  H  N N 137 
ALA   HB3  H  N N 138 
ALA   HXT  H  N N 139 
ARG   N    N  N N 140 
ARG   CA   C  N S 141 
ARG   C    C  N N 142 
ARG   O    O  N N 143 
ARG   CB   C  N N 144 
ARG   CG   C  N N 145 
ARG   CD   C  N N 146 
ARG   NE   N  N N 147 
ARG   CZ   C  N N 148 
ARG   NH1  N  N N 149 
ARG   NH2  N  N N 150 
ARG   OXT  O  N N 151 
ARG   H    H  N N 152 
ARG   H2   H  N N 153 
ARG   HA   H  N N 154 
ARG   HB2  H  N N 155 
ARG   HB3  H  N N 156 
ARG   HG2  H  N N 157 
ARG   HG3  H  N N 158 
ARG   HD2  H  N N 159 
ARG   HD3  H  N N 160 
ARG   HE   H  N N 161 
ARG   HH11 H  N N 162 
ARG   HH12 H  N N 163 
ARG   HH21 H  N N 164 
ARG   HH22 H  N N 165 
ARG   HXT  H  N N 166 
ASN   N    N  N N 167 
ASN   CA   C  N S 168 
ASN   C    C  N N 169 
ASN   O    O  N N 170 
ASN   CB   C  N N 171 
ASN   CG   C  N N 172 
ASN   OD1  O  N N 173 
ASN   ND2  N  N N 174 
ASN   OXT  O  N N 175 
ASN   H    H  N N 176 
ASN   H2   H  N N 177 
ASN   HA   H  N N 178 
ASN   HB2  H  N N 179 
ASN   HB3  H  N N 180 
ASN   HD21 H  N N 181 
ASN   HD22 H  N N 182 
ASN   HXT  H  N N 183 
ASP   N    N  N N 184 
ASP   CA   C  N S 185 
ASP   C    C  N N 186 
ASP   O    O  N N 187 
ASP   CB   C  N N 188 
ASP   CG   C  N N 189 
ASP   OD1  O  N N 190 
ASP   OD2  O  N N 191 
ASP   OXT  O  N N 192 
ASP   H    H  N N 193 
ASP   H2   H  N N 194 
ASP   HA   H  N N 195 
ASP   HB2  H  N N 196 
ASP   HB3  H  N N 197 
ASP   HD2  H  N N 198 
ASP   HXT  H  N N 199 
CYS   N    N  N N 200 
CYS   CA   C  N R 201 
CYS   C    C  N N 202 
CYS   O    O  N N 203 
CYS   CB   C  N N 204 
CYS   SG   S  N N 205 
CYS   OXT  O  N N 206 
CYS   H    H  N N 207 
CYS   H2   H  N N 208 
CYS   HA   H  N N 209 
CYS   HB2  H  N N 210 
CYS   HB3  H  N N 211 
CYS   HG   H  N N 212 
CYS   HXT  H  N N 213 
GLN   N    N  N N 214 
GLN   CA   C  N S 215 
GLN   C    C  N N 216 
GLN   O    O  N N 217 
GLN   CB   C  N N 218 
GLN   CG   C  N N 219 
GLN   CD   C  N N 220 
GLN   OE1  O  N N 221 
GLN   NE2  N  N N 222 
GLN   OXT  O  N N 223 
GLN   H    H  N N 224 
GLN   H2   H  N N 225 
GLN   HA   H  N N 226 
GLN   HB2  H  N N 227 
GLN   HB3  H  N N 228 
GLN   HG2  H  N N 229 
GLN   HG3  H  N N 230 
GLN   HE21 H  N N 231 
GLN   HE22 H  N N 232 
GLN   HXT  H  N N 233 
GLU   N    N  N N 234 
GLU   CA   C  N S 235 
GLU   C    C  N N 236 
GLU   O    O  N N 237 
GLU   CB   C  N N 238 
GLU   CG   C  N N 239 
GLU   CD   C  N N 240 
GLU   OE1  O  N N 241 
GLU   OE2  O  N N 242 
GLU   OXT  O  N N 243 
GLU   H    H  N N 244 
GLU   H2   H  N N 245 
GLU   HA   H  N N 246 
GLU   HB2  H  N N 247 
GLU   HB3  H  N N 248 
GLU   HG2  H  N N 249 
GLU   HG3  H  N N 250 
GLU   HE2  H  N N 251 
GLU   HXT  H  N N 252 
GLY   N    N  N N 253 
GLY   CA   C  N N 254 
GLY   C    C  N N 255 
GLY   O    O  N N 256 
GLY   OXT  O  N N 257 
GLY   H    H  N N 258 
GLY   H2   H  N N 259 
GLY   HA2  H  N N 260 
GLY   HA3  H  N N 261 
GLY   HXT  H  N N 262 
HIS   N    N  N N 263 
HIS   CA   C  N S 264 
HIS   C    C  N N 265 
HIS   O    O  N N 266 
HIS   CB   C  N N 267 
HIS   CG   C  Y N 268 
HIS   ND1  N  Y N 269 
HIS   CD2  C  Y N 270 
HIS   CE1  C  Y N 271 
HIS   NE2  N  Y N 272 
HIS   OXT  O  N N 273 
HIS   H    H  N N 274 
HIS   H2   H  N N 275 
HIS   HA   H  N N 276 
HIS   HB2  H  N N 277 
HIS   HB3  H  N N 278 
HIS   HD1  H  N N 279 
HIS   HD2  H  N N 280 
HIS   HE1  H  N N 281 
HIS   HE2  H  N N 282 
HIS   HXT  H  N N 283 
HOH   O    O  N N 284 
HOH   H1   H  N N 285 
HOH   H2   H  N N 286 
ILE   N    N  N N 287 
ILE   CA   C  N S 288 
ILE   C    C  N N 289 
ILE   O    O  N N 290 
ILE   CB   C  N S 291 
ILE   CG1  C  N N 292 
ILE   CG2  C  N N 293 
ILE   CD1  C  N N 294 
ILE   OXT  O  N N 295 
ILE   H    H  N N 296 
ILE   H2   H  N N 297 
ILE   HA   H  N N 298 
ILE   HB   H  N N 299 
ILE   HG12 H  N N 300 
ILE   HG13 H  N N 301 
ILE   HG21 H  N N 302 
ILE   HG22 H  N N 303 
ILE   HG23 H  N N 304 
ILE   HD11 H  N N 305 
ILE   HD12 H  N N 306 
ILE   HD13 H  N N 307 
ILE   HXT  H  N N 308 
LEU   N    N  N N 309 
LEU   CA   C  N S 310 
LEU   C    C  N N 311 
LEU   O    O  N N 312 
LEU   CB   C  N N 313 
LEU   CG   C  N N 314 
LEU   CD1  C  N N 315 
LEU   CD2  C  N N 316 
LEU   OXT  O  N N 317 
LEU   H    H  N N 318 
LEU   H2   H  N N 319 
LEU   HA   H  N N 320 
LEU   HB2  H  N N 321 
LEU   HB3  H  N N 322 
LEU   HG   H  N N 323 
LEU   HD11 H  N N 324 
LEU   HD12 H  N N 325 
LEU   HD13 H  N N 326 
LEU   HD21 H  N N 327 
LEU   HD22 H  N N 328 
LEU   HD23 H  N N 329 
LEU   HXT  H  N N 330 
LYS   N    N  N N 331 
LYS   CA   C  N S 332 
LYS   C    C  N N 333 
LYS   O    O  N N 334 
LYS   CB   C  N N 335 
LYS   CG   C  N N 336 
LYS   CD   C  N N 337 
LYS   CE   C  N N 338 
LYS   NZ   N  N N 339 
LYS   OXT  O  N N 340 
LYS   H    H  N N 341 
LYS   H2   H  N N 342 
LYS   HA   H  N N 343 
LYS   HB2  H  N N 344 
LYS   HB3  H  N N 345 
LYS   HG2  H  N N 346 
LYS   HG3  H  N N 347 
LYS   HD2  H  N N 348 
LYS   HD3  H  N N 349 
LYS   HE2  H  N N 350 
LYS   HE3  H  N N 351 
LYS   HZ1  H  N N 352 
LYS   HZ2  H  N N 353 
LYS   HZ3  H  N N 354 
LYS   HXT  H  N N 355 
MET   N    N  N N 356 
MET   CA   C  N S 357 
MET   C    C  N N 358 
MET   O    O  N N 359 
MET   CB   C  N N 360 
MET   CG   C  N N 361 
MET   SD   S  N N 362 
MET   CE   C  N N 363 
MET   OXT  O  N N 364 
MET   H    H  N N 365 
MET   H2   H  N N 366 
MET   HA   H  N N 367 
MET   HB2  H  N N 368 
MET   HB3  H  N N 369 
MET   HG2  H  N N 370 
MET   HG3  H  N N 371 
MET   HE1  H  N N 372 
MET   HE2  H  N N 373 
MET   HE3  H  N N 374 
MET   HXT  H  N N 375 
PHE   N    N  N N 376 
PHE   CA   C  N S 377 
PHE   C    C  N N 378 
PHE   O    O  N N 379 
PHE   CB   C  N N 380 
PHE   CG   C  Y N 381 
PHE   CD1  C  Y N 382 
PHE   CD2  C  Y N 383 
PHE   CE1  C  Y N 384 
PHE   CE2  C  Y N 385 
PHE   CZ   C  Y N 386 
PHE   OXT  O  N N 387 
PHE   H    H  N N 388 
PHE   H2   H  N N 389 
PHE   HA   H  N N 390 
PHE   HB2  H  N N 391 
PHE   HB3  H  N N 392 
PHE   HD1  H  N N 393 
PHE   HD2  H  N N 394 
PHE   HE1  H  N N 395 
PHE   HE2  H  N N 396 
PHE   HZ   H  N N 397 
PHE   HXT  H  N N 398 
PRO   N    N  N N 399 
PRO   CA   C  N S 400 
PRO   C    C  N N 401 
PRO   O    O  N N 402 
PRO   CB   C  N N 403 
PRO   CG   C  N N 404 
PRO   CD   C  N N 405 
PRO   OXT  O  N N 406 
PRO   H    H  N N 407 
PRO   HA   H  N N 408 
PRO   HB2  H  N N 409 
PRO   HB3  H  N N 410 
PRO   HG2  H  N N 411 
PRO   HG3  H  N N 412 
PRO   HD2  H  N N 413 
PRO   HD3  H  N N 414 
PRO   HXT  H  N N 415 
SER   N    N  N N 416 
SER   CA   C  N S 417 
SER   C    C  N N 418 
SER   O    O  N N 419 
SER   CB   C  N N 420 
SER   OG   O  N N 421 
SER   OXT  O  N N 422 
SER   H    H  N N 423 
SER   H2   H  N N 424 
SER   HA   H  N N 425 
SER   HB2  H  N N 426 
SER   HB3  H  N N 427 
SER   HG   H  N N 428 
SER   HXT  H  N N 429 
THR   N    N  N N 430 
THR   CA   C  N S 431 
THR   C    C  N N 432 
THR   O    O  N N 433 
THR   CB   C  N R 434 
THR   OG1  O  N N 435 
THR   CG2  C  N N 436 
THR   OXT  O  N N 437 
THR   H    H  N N 438 
THR   H2   H  N N 439 
THR   HA   H  N N 440 
THR   HB   H  N N 441 
THR   HG1  H  N N 442 
THR   HG21 H  N N 443 
THR   HG22 H  N N 444 
THR   HG23 H  N N 445 
THR   HXT  H  N N 446 
TRP   N    N  N N 447 
TRP   CA   C  N S 448 
TRP   C    C  N N 449 
TRP   O    O  N N 450 
TRP   CB   C  N N 451 
TRP   CG   C  Y N 452 
TRP   CD1  C  Y N 453 
TRP   CD2  C  Y N 454 
TRP   NE1  N  Y N 455 
TRP   CE2  C  Y N 456 
TRP   CE3  C  Y N 457 
TRP   CZ2  C  Y N 458 
TRP   CZ3  C  Y N 459 
TRP   CH2  C  Y N 460 
TRP   OXT  O  N N 461 
TRP   H    H  N N 462 
TRP   H2   H  N N 463 
TRP   HA   H  N N 464 
TRP   HB2  H  N N 465 
TRP   HB3  H  N N 466 
TRP   HD1  H  N N 467 
TRP   HE1  H  N N 468 
TRP   HE3  H  N N 469 
TRP   HZ2  H  N N 470 
TRP   HZ3  H  N N 471 
TRP   HH2  H  N N 472 
TRP   HXT  H  N N 473 
TYR   N    N  N N 474 
TYR   CA   C  N S 475 
TYR   C    C  N N 476 
TYR   O    O  N N 477 
TYR   CB   C  N N 478 
TYR   CG   C  Y N 479 
TYR   CD1  C  Y N 480 
TYR   CD2  C  Y N 481 
TYR   CE1  C  Y N 482 
TYR   CE2  C  Y N 483 
TYR   CZ   C  Y N 484 
TYR   OH   O  N N 485 
TYR   OXT  O  N N 486 
TYR   H    H  N N 487 
TYR   H2   H  N N 488 
TYR   HA   H  N N 489 
TYR   HB2  H  N N 490 
TYR   HB3  H  N N 491 
TYR   HD1  H  N N 492 
TYR   HD2  H  N N 493 
TYR   HE1  H  N N 494 
TYR   HE2  H  N N 495 
TYR   HH   H  N N 496 
TYR   HXT  H  N N 497 
VAL   N    N  N N 498 
VAL   CA   C  N S 499 
VAL   C    C  N N 500 
VAL   O    O  N N 501 
VAL   CB   C  N N 502 
VAL   CG1  C  N N 503 
VAL   CG2  C  N N 504 
VAL   OXT  O  N N 505 
VAL   H    H  N N 506 
VAL   H2   H  N N 507 
VAL   HA   H  N N 508 
VAL   HB   H  N N 509 
VAL   HG11 H  N N 510 
VAL   HG12 H  N N 511 
VAL   HG13 H  N N 512 
VAL   HG21 H  N N 513 
VAL   HG22 H  N N 514 
VAL   HG23 H  N N 515 
VAL   HXT  H  N N 516 
ZN    ZN   ZN N N 517 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1H09 O16 C15  sing N N 1   
A1H09 O16 C16  sing N N 2   
A1H09 C18 C15  sing N N 3   
A1H09 C18 O20  sing N N 4   
A1H09 C15 C17  sing N N 5   
A1H09 C16 O17  sing N N 6   
A1H09 C16 C8   sing N N 7   
A1H09 O18 C8   sing N N 8   
A1H09 C8  C17  sing N N 9   
A1H09 C17 O19  sing N N 10  
A1H09 O19 P2   sing N N 11  
A1H09 O23 C23  sing N N 12  
A1H09 P2  O9   doub N N 13  
A1H09 P2  O53  sing N N 14  
A1H09 P2  O8   sing N N 15  
A1H09 C53 O53  sing N N 16  
A1H09 C53 C43  sing N N 17  
A1H09 O43 C43  sing N N 18  
A1H09 C23 C33  sing N N 19  
A1H09 C23 C13  sing N N 20  
A1H09 C33 C43  sing N N 21  
A1H09 C33 O33  sing N N 22  
A1H09 C13 O12  sing N N 23  
A1H09 C14 O15  sing N N 24  
A1H09 C14 C9   sing N N 25  
A1H09 O12 C6   sing N N 26  
A1H09 O10 C9   sing N N 27  
A1H09 O10 C6   sing N N 28  
A1H09 C9  C10  sing N N 29  
A1H09 C6  C7   sing N N 30  
A1H09 C10 C7   sing N N 31  
A1H09 C10 O14  sing N N 32  
A1H09 C7  O13  sing N N 33  
A1H09 O7  P1   doub N N 34  
A1H09 O14 P1   sing N N 35  
A1H09 P1  O51  sing N N 36  
A1H09 P1  O6   sing N N 37  
A1H09 C52 O52  sing N N 38  
A1H09 C52 C42  sing N N 39  
A1H09 O51 C51  sing N N 40  
A1H09 O42 C42  sing N N 41  
A1H09 O42 C12  sing N N 42  
A1H09 C42 C32  sing N N 43  
A1H09 O41 C41  sing N N 44  
A1H09 C51 C41  sing N N 45  
A1H09 C11 O11  sing N N 46  
A1H09 C11 C21  sing N N 47  
A1H09 C12 O11  sing N N 48  
A1H09 C12 C22  sing N N 49  
A1H09 C41 C31  sing N N 50  
A1H09 C32 O32  sing N N 51  
A1H09 C32 C22  sing N N 52  
A1H09 O32 P    sing N N 53  
A1H09 C31 C21  sing N N 54  
A1H09 C31 O31  sing N N 55  
A1H09 O22 C22  sing N N 56  
A1H09 C21 O21  sing N N 57  
A1H09 O1P P    doub N N 58  
A1H09 P   O2P  sing N N 59  
A1H09 P   O5   sing N N 60  
A1H09 O1  C1   sing N N 61  
A1H09 O5  C5   sing N N 62  
A1H09 O3  C3   sing N N 63  
A1H09 C1  C2   sing N N 64  
A1H09 C5  C4   sing N N 65  
A1H09 C3  C2   sing N N 66  
A1H09 C3  C4   sing N N 67  
A1H09 C2  O2   sing N N 68  
A1H09 C4  O4   sing N N 69  
A1H09 C1  H1   sing N N 70  
A1H09 C1  H2   sing N N 71  
A1H09 C2  H3   sing N N 72  
A1H09 C3  H4   sing N N 73  
A1H09 C4  H5   sing N N 74  
A1H09 C5  H6   sing N N 75  
A1H09 C5  H7   sing N N 76  
A1H09 O6  H8   sing N N 77  
A1H09 C7  H9   sing N N 78  
A1H09 O8  H10  sing N N 79  
A1H09 C9  H11  sing N N 80  
A1H09 C11 H12  sing N N 81  
A1H09 C11 H13  sing N N 82  
A1H09 O13 H14  sing N N 83  
A1H09 C15 H15  sing N N 84  
A1H09 C16 H16  sing N N 85  
A1H09 C17 H17  sing N N 86  
A1H09 C18 H18  sing N N 87  
A1H09 C18 H19  sing N N 88  
A1H09 C21 H20  sing N N 89  
A1H09 C22 H21  sing N N 90  
A1H09 O1  H22  sing N N 91  
A1H09 O2  H23  sing N N 92  
A1H09 O3  H24  sing N N 93  
A1H09 O4  H25  sing N N 94  
A1H09 O2P H26  sing N N 95  
A1H09 O21 H27  sing N N 96  
A1H09 C31 H28  sing N N 97  
A1H09 O31 H29  sing N N 98  
A1H09 C41 H30  sing N N 99  
A1H09 O41 H31  sing N N 100 
A1H09 C51 H32  sing N N 101 
A1H09 C51 H33  sing N N 102 
A1H09 C42 H34  sing N N 103 
A1H09 C12 H35  sing N N 104 
A1H09 O22 H36  sing N N 105 
A1H09 C32 H37  sing N N 106 
A1H09 C52 H38  sing N N 107 
A1H09 C52 H39  sing N N 108 
A1H09 O52 H40  sing N N 109 
A1H09 C13 H41  sing N N 110 
A1H09 C13 H42  sing N N 111 
A1H09 C23 H43  sing N N 112 
A1H09 C33 H44  sing N N 113 
A1H09 C43 H45  sing N N 114 
A1H09 C53 H46  sing N N 115 
A1H09 C53 H47  sing N N 116 
A1H09 C6  H48  sing N N 117 
A1H09 C8  H49  sing N N 118 
A1H09 O23 H50  sing N N 119 
A1H09 O33 H51  sing N N 120 
A1H09 O43 H52  sing N N 121 
A1H09 C10 H53  sing N N 122 
A1H09 C14 H54  sing N N 123 
A1H09 C14 H55  sing N N 124 
A1H09 O15 H56  sing N N 125 
A1H09 O17 H57  sing N N 126 
A1H09 O18 H58  sing N N 127 
A1H09 O20 H59  sing N N 128 
ALA   N   CA   sing N N 129 
ALA   N   H    sing N N 130 
ALA   N   H2   sing N N 131 
ALA   CA  C    sing N N 132 
ALA   CA  CB   sing N N 133 
ALA   CA  HA   sing N N 134 
ALA   C   O    doub N N 135 
ALA   C   OXT  sing N N 136 
ALA   CB  HB1  sing N N 137 
ALA   CB  HB2  sing N N 138 
ALA   CB  HB3  sing N N 139 
ALA   OXT HXT  sing N N 140 
ARG   N   CA   sing N N 141 
ARG   N   H    sing N N 142 
ARG   N   H2   sing N N 143 
ARG   CA  C    sing N N 144 
ARG   CA  CB   sing N N 145 
ARG   CA  HA   sing N N 146 
ARG   C   O    doub N N 147 
ARG   C   OXT  sing N N 148 
ARG   CB  CG   sing N N 149 
ARG   CB  HB2  sing N N 150 
ARG   CB  HB3  sing N N 151 
ARG   CG  CD   sing N N 152 
ARG   CG  HG2  sing N N 153 
ARG   CG  HG3  sing N N 154 
ARG   CD  NE   sing N N 155 
ARG   CD  HD2  sing N N 156 
ARG   CD  HD3  sing N N 157 
ARG   NE  CZ   sing N N 158 
ARG   NE  HE   sing N N 159 
ARG   CZ  NH1  sing N N 160 
ARG   CZ  NH2  doub N N 161 
ARG   NH1 HH11 sing N N 162 
ARG   NH1 HH12 sing N N 163 
ARG   NH2 HH21 sing N N 164 
ARG   NH2 HH22 sing N N 165 
ARG   OXT HXT  sing N N 166 
ASN   N   CA   sing N N 167 
ASN   N   H    sing N N 168 
ASN   N   H2   sing N N 169 
ASN   CA  C    sing N N 170 
ASN   CA  CB   sing N N 171 
ASN   CA  HA   sing N N 172 
ASN   C   O    doub N N 173 
ASN   C   OXT  sing N N 174 
ASN   CB  CG   sing N N 175 
ASN   CB  HB2  sing N N 176 
ASN   CB  HB3  sing N N 177 
ASN   CG  OD1  doub N N 178 
ASN   CG  ND2  sing N N 179 
ASN   ND2 HD21 sing N N 180 
ASN   ND2 HD22 sing N N 181 
ASN   OXT HXT  sing N N 182 
ASP   N   CA   sing N N 183 
ASP   N   H    sing N N 184 
ASP   N   H2   sing N N 185 
ASP   CA  C    sing N N 186 
ASP   CA  CB   sing N N 187 
ASP   CA  HA   sing N N 188 
ASP   C   O    doub N N 189 
ASP   C   OXT  sing N N 190 
ASP   CB  CG   sing N N 191 
ASP   CB  HB2  sing N N 192 
ASP   CB  HB3  sing N N 193 
ASP   CG  OD1  doub N N 194 
ASP   CG  OD2  sing N N 195 
ASP   OD2 HD2  sing N N 196 
ASP   OXT HXT  sing N N 197 
CYS   N   CA   sing N N 198 
CYS   N   H    sing N N 199 
CYS   N   H2   sing N N 200 
CYS   CA  C    sing N N 201 
CYS   CA  CB   sing N N 202 
CYS   CA  HA   sing N N 203 
CYS   C   O    doub N N 204 
CYS   C   OXT  sing N N 205 
CYS   CB  SG   sing N N 206 
CYS   CB  HB2  sing N N 207 
CYS   CB  HB3  sing N N 208 
CYS   SG  HG   sing N N 209 
CYS   OXT HXT  sing N N 210 
GLN   N   CA   sing N N 211 
GLN   N   H    sing N N 212 
GLN   N   H2   sing N N 213 
GLN   CA  C    sing N N 214 
GLN   CA  CB   sing N N 215 
GLN   CA  HA   sing N N 216 
GLN   C   O    doub N N 217 
GLN   C   OXT  sing N N 218 
GLN   CB  CG   sing N N 219 
GLN   CB  HB2  sing N N 220 
GLN   CB  HB3  sing N N 221 
GLN   CG  CD   sing N N 222 
GLN   CG  HG2  sing N N 223 
GLN   CG  HG3  sing N N 224 
GLN   CD  OE1  doub N N 225 
GLN   CD  NE2  sing N N 226 
GLN   NE2 HE21 sing N N 227 
GLN   NE2 HE22 sing N N 228 
GLN   OXT HXT  sing N N 229 
GLU   N   CA   sing N N 230 
GLU   N   H    sing N N 231 
GLU   N   H2   sing N N 232 
GLU   CA  C    sing N N 233 
GLU   CA  CB   sing N N 234 
GLU   CA  HA   sing N N 235 
GLU   C   O    doub N N 236 
GLU   C   OXT  sing N N 237 
GLU   CB  CG   sing N N 238 
GLU   CB  HB2  sing N N 239 
GLU   CB  HB3  sing N N 240 
GLU   CG  CD   sing N N 241 
GLU   CG  HG2  sing N N 242 
GLU   CG  HG3  sing N N 243 
GLU   CD  OE1  doub N N 244 
GLU   CD  OE2  sing N N 245 
GLU   OE2 HE2  sing N N 246 
GLU   OXT HXT  sing N N 247 
GLY   N   CA   sing N N 248 
GLY   N   H    sing N N 249 
GLY   N   H2   sing N N 250 
GLY   CA  C    sing N N 251 
GLY   CA  HA2  sing N N 252 
GLY   CA  HA3  sing N N 253 
GLY   C   O    doub N N 254 
GLY   C   OXT  sing N N 255 
GLY   OXT HXT  sing N N 256 
HIS   N   CA   sing N N 257 
HIS   N   H    sing N N 258 
HIS   N   H2   sing N N 259 
HIS   CA  C    sing N N 260 
HIS   CA  CB   sing N N 261 
HIS   CA  HA   sing N N 262 
HIS   C   O    doub N N 263 
HIS   C   OXT  sing N N 264 
HIS   CB  CG   sing N N 265 
HIS   CB  HB2  sing N N 266 
HIS   CB  HB3  sing N N 267 
HIS   CG  ND1  sing Y N 268 
HIS   CG  CD2  doub Y N 269 
HIS   ND1 CE1  doub Y N 270 
HIS   ND1 HD1  sing N N 271 
HIS   CD2 NE2  sing Y N 272 
HIS   CD2 HD2  sing N N 273 
HIS   CE1 NE2  sing Y N 274 
HIS   CE1 HE1  sing N N 275 
HIS   NE2 HE2  sing N N 276 
HIS   OXT HXT  sing N N 277 
HOH   O   H1   sing N N 278 
HOH   O   H2   sing N N 279 
ILE   N   CA   sing N N 280 
ILE   N   H    sing N N 281 
ILE   N   H2   sing N N 282 
ILE   CA  C    sing N N 283 
ILE   CA  CB   sing N N 284 
ILE   CA  HA   sing N N 285 
ILE   C   O    doub N N 286 
ILE   C   OXT  sing N N 287 
ILE   CB  CG1  sing N N 288 
ILE   CB  CG2  sing N N 289 
ILE   CB  HB   sing N N 290 
ILE   CG1 CD1  sing N N 291 
ILE   CG1 HG12 sing N N 292 
ILE   CG1 HG13 sing N N 293 
ILE   CG2 HG21 sing N N 294 
ILE   CG2 HG22 sing N N 295 
ILE   CG2 HG23 sing N N 296 
ILE   CD1 HD11 sing N N 297 
ILE   CD1 HD12 sing N N 298 
ILE   CD1 HD13 sing N N 299 
ILE   OXT HXT  sing N N 300 
LEU   N   CA   sing N N 301 
LEU   N   H    sing N N 302 
LEU   N   H2   sing N N 303 
LEU   CA  C    sing N N 304 
LEU   CA  CB   sing N N 305 
LEU   CA  HA   sing N N 306 
LEU   C   O    doub N N 307 
LEU   C   OXT  sing N N 308 
LEU   CB  CG   sing N N 309 
LEU   CB  HB2  sing N N 310 
LEU   CB  HB3  sing N N 311 
LEU   CG  CD1  sing N N 312 
LEU   CG  CD2  sing N N 313 
LEU   CG  HG   sing N N 314 
LEU   CD1 HD11 sing N N 315 
LEU   CD1 HD12 sing N N 316 
LEU   CD1 HD13 sing N N 317 
LEU   CD2 HD21 sing N N 318 
LEU   CD2 HD22 sing N N 319 
LEU   CD2 HD23 sing N N 320 
LEU   OXT HXT  sing N N 321 
LYS   N   CA   sing N N 322 
LYS   N   H    sing N N 323 
LYS   N   H2   sing N N 324 
LYS   CA  C    sing N N 325 
LYS   CA  CB   sing N N 326 
LYS   CA  HA   sing N N 327 
LYS   C   O    doub N N 328 
LYS   C   OXT  sing N N 329 
LYS   CB  CG   sing N N 330 
LYS   CB  HB2  sing N N 331 
LYS   CB  HB3  sing N N 332 
LYS   CG  CD   sing N N 333 
LYS   CG  HG2  sing N N 334 
LYS   CG  HG3  sing N N 335 
LYS   CD  CE   sing N N 336 
LYS   CD  HD2  sing N N 337 
LYS   CD  HD3  sing N N 338 
LYS   CE  NZ   sing N N 339 
LYS   CE  HE2  sing N N 340 
LYS   CE  HE3  sing N N 341 
LYS   NZ  HZ1  sing N N 342 
LYS   NZ  HZ2  sing N N 343 
LYS   NZ  HZ3  sing N N 344 
LYS   OXT HXT  sing N N 345 
MET   N   CA   sing N N 346 
MET   N   H    sing N N 347 
MET   N   H2   sing N N 348 
MET   CA  C    sing N N 349 
MET   CA  CB   sing N N 350 
MET   CA  HA   sing N N 351 
MET   C   O    doub N N 352 
MET   C   OXT  sing N N 353 
MET   CB  CG   sing N N 354 
MET   CB  HB2  sing N N 355 
MET   CB  HB3  sing N N 356 
MET   CG  SD   sing N N 357 
MET   CG  HG2  sing N N 358 
MET   CG  HG3  sing N N 359 
MET   SD  CE   sing N N 360 
MET   CE  HE1  sing N N 361 
MET   CE  HE2  sing N N 362 
MET   CE  HE3  sing N N 363 
MET   OXT HXT  sing N N 364 
PHE   N   CA   sing N N 365 
PHE   N   H    sing N N 366 
PHE   N   H2   sing N N 367 
PHE   CA  C    sing N N 368 
PHE   CA  CB   sing N N 369 
PHE   CA  HA   sing N N 370 
PHE   C   O    doub N N 371 
PHE   C   OXT  sing N N 372 
PHE   CB  CG   sing N N 373 
PHE   CB  HB2  sing N N 374 
PHE   CB  HB3  sing N N 375 
PHE   CG  CD1  doub Y N 376 
PHE   CG  CD2  sing Y N 377 
PHE   CD1 CE1  sing Y N 378 
PHE   CD1 HD1  sing N N 379 
PHE   CD2 CE2  doub Y N 380 
PHE   CD2 HD2  sing N N 381 
PHE   CE1 CZ   doub Y N 382 
PHE   CE1 HE1  sing N N 383 
PHE   CE2 CZ   sing Y N 384 
PHE   CE2 HE2  sing N N 385 
PHE   CZ  HZ   sing N N 386 
PHE   OXT HXT  sing N N 387 
PRO   N   CA   sing N N 388 
PRO   N   CD   sing N N 389 
PRO   N   H    sing N N 390 
PRO   CA  C    sing N N 391 
PRO   CA  CB   sing N N 392 
PRO   CA  HA   sing N N 393 
PRO   C   O    doub N N 394 
PRO   C   OXT  sing N N 395 
PRO   CB  CG   sing N N 396 
PRO   CB  HB2  sing N N 397 
PRO   CB  HB3  sing N N 398 
PRO   CG  CD   sing N N 399 
PRO   CG  HG2  sing N N 400 
PRO   CG  HG3  sing N N 401 
PRO   CD  HD2  sing N N 402 
PRO   CD  HD3  sing N N 403 
PRO   OXT HXT  sing N N 404 
SER   N   CA   sing N N 405 
SER   N   H    sing N N 406 
SER   N   H2   sing N N 407 
SER   CA  C    sing N N 408 
SER   CA  CB   sing N N 409 
SER   CA  HA   sing N N 410 
SER   C   O    doub N N 411 
SER   C   OXT  sing N N 412 
SER   CB  OG   sing N N 413 
SER   CB  HB2  sing N N 414 
SER   CB  HB3  sing N N 415 
SER   OG  HG   sing N N 416 
SER   OXT HXT  sing N N 417 
THR   N   CA   sing N N 418 
THR   N   H    sing N N 419 
THR   N   H2   sing N N 420 
THR   CA  C    sing N N 421 
THR   CA  CB   sing N N 422 
THR   CA  HA   sing N N 423 
THR   C   O    doub N N 424 
THR   C   OXT  sing N N 425 
THR   CB  OG1  sing N N 426 
THR   CB  CG2  sing N N 427 
THR   CB  HB   sing N N 428 
THR   OG1 HG1  sing N N 429 
THR   CG2 HG21 sing N N 430 
THR   CG2 HG22 sing N N 431 
THR   CG2 HG23 sing N N 432 
THR   OXT HXT  sing N N 433 
TRP   N   CA   sing N N 434 
TRP   N   H    sing N N 435 
TRP   N   H2   sing N N 436 
TRP   CA  C    sing N N 437 
TRP   CA  CB   sing N N 438 
TRP   CA  HA   sing N N 439 
TRP   C   O    doub N N 440 
TRP   C   OXT  sing N N 441 
TRP   CB  CG   sing N N 442 
TRP   CB  HB2  sing N N 443 
TRP   CB  HB3  sing N N 444 
TRP   CG  CD1  doub Y N 445 
TRP   CG  CD2  sing Y N 446 
TRP   CD1 NE1  sing Y N 447 
TRP   CD1 HD1  sing N N 448 
TRP   CD2 CE2  doub Y N 449 
TRP   CD2 CE3  sing Y N 450 
TRP   NE1 CE2  sing Y N 451 
TRP   NE1 HE1  sing N N 452 
TRP   CE2 CZ2  sing Y N 453 
TRP   CE3 CZ3  doub Y N 454 
TRP   CE3 HE3  sing N N 455 
TRP   CZ2 CH2  doub Y N 456 
TRP   CZ2 HZ2  sing N N 457 
TRP   CZ3 CH2  sing Y N 458 
TRP   CZ3 HZ3  sing N N 459 
TRP   CH2 HH2  sing N N 460 
TRP   OXT HXT  sing N N 461 
TYR   N   CA   sing N N 462 
TYR   N   H    sing N N 463 
TYR   N   H2   sing N N 464 
TYR   CA  C    sing N N 465 
TYR   CA  CB   sing N N 466 
TYR   CA  HA   sing N N 467 
TYR   C   O    doub N N 468 
TYR   C   OXT  sing N N 469 
TYR   CB  CG   sing N N 470 
TYR   CB  HB2  sing N N 471 
TYR   CB  HB3  sing N N 472 
TYR   CG  CD1  doub Y N 473 
TYR   CG  CD2  sing Y N 474 
TYR   CD1 CE1  sing Y N 475 
TYR   CD1 HD1  sing N N 476 
TYR   CD2 CE2  doub Y N 477 
TYR   CD2 HD2  sing N N 478 
TYR   CE1 CZ   doub Y N 479 
TYR   CE1 HE1  sing N N 480 
TYR   CE2 CZ   sing Y N 481 
TYR   CE2 HE2  sing N N 482 
TYR   CZ  OH   sing N N 483 
TYR   OH  HH   sing N N 484 
TYR   OXT HXT  sing N N 485 
VAL   N   CA   sing N N 486 
VAL   N   H    sing N N 487 
VAL   N   H2   sing N N 488 
VAL   CA  C    sing N N 489 
VAL   CA  CB   sing N N 490 
VAL   CA  HA   sing N N 491 
VAL   C   O    doub N N 492 
VAL   C   OXT  sing N N 493 
VAL   CB  CG1  sing N N 494 
VAL   CB  CG2  sing N N 495 
VAL   CB  HB   sing N N 496 
VAL   CG1 HG11 sing N N 497 
VAL   CG1 HG12 sing N N 498 
VAL   CG1 HG13 sing N N 499 
VAL   CG2 HG21 sing N N 500 
VAL   CG2 HG22 sing N N 501 
VAL   CG2 HG23 sing N N 502 
VAL   OXT HXT  sing N N 503 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1H09 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1H09 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.entity_id_list 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
_pdbx_initial_refinement_model.details 
1 ? 'experimental model' PDB 3KYM ? 
2 ? 'experimental model' PDB 6AZM ? 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8RDF 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016413 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007617 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006898 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 7.96527  ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135  5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ? ? 2.14387  29.76375 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLU   A 1 1   ? -6.82700  -5.59200 -19.17400 1.000 48.99587  ? 1   GLU   H N   1 
ATOM   2    C  CA  . GLU   A 1 1   ? -6.27800  -4.49800 -18.38300 1.000 44.22263  ? 1   GLU   H CA  1 
ATOM   3    C  C   . GLU   A 1 1   ? -5.99900  -3.27500 -19.24800 1.000 39.57985  ? 1   GLU   H C   1 
ATOM   4    O  O   . GLU   A 1 1   ? -4.94300  -3.17800 -19.87200 1.000 40.78215  ? 1   GLU   H O   1 
ATOM   5    C  CB  . GLU   A 1 1   ? -4.99100  -4.93700 -17.67400 1.000 39.67828  ? 1   GLU   H CB  1 
ATOM   6    C  CG  . GLU   A 1 1   ? -4.68300  -4.17200 -16.38800 1.000 47.07127  ? 1   GLU   H CG  1 
ATOM   7    C  CD  . GLU   A 1 1   ? -3.74600  -4.92800 -15.45800 1.000 62.02546  ? 1   GLU   H CD  1 
ATOM   8    O  OE1 . GLU   A 1 1   ? -2.93800  -5.74800 -15.94600 1.000 59.24297  ? 1   GLU   H OE1 1 
ATOM   9    O  OE2 . GLU   A 1 1   ? -3.83800  -4.72500 -14.22900 1.000 76.05939  ? 1   GLU   H OE2 1 
ATOM   10   N  N   . VAL   A 1 2   ? -6.95500  -2.34700 -19.28900 1.000 33.32752  ? 2   VAL   H N   1 
ATOM   11   C  CA  . VAL   A 1 2   ? -6.73500  -1.07600 -19.96500 1.000 29.08342  ? 2   VAL   H CA  1 
ATOM   12   C  C   . VAL   A 1 2   ? -5.79700  -0.22700 -19.12000 1.000 32.67824  ? 2   VAL   H C   1 
ATOM   13   O  O   . VAL   A 1 2   ? -6.05300  0.01400  -17.93300 1.000 39.61877  ? 2   VAL   H O   1 
ATOM   14   C  CB  . VAL   A 1 2   ? -8.06800  -0.35500 -20.21200 1.000 32.37151  ? 2   VAL   H CB  1 
ATOM   15   C  CG1 . VAL   A 1 2   ? -7.82800  1.11800  -20.50100 1.000 34.47354  ? 2   VAL   H CG1 1 
ATOM   16   C  CG2 . VAL   A 1 2   ? -8.82600  -1.01000 -21.35400 1.000 28.46804  ? 2   VAL   H CG2 1 
ATOM   17   N  N   . GLN   A 1 3   ? -4.69300  0.21700  -19.71900 1.000 32.39598  ? 3   GLN   H N   1 
ATOM   18   C  CA  . GLN   A 1 3   ? -3.66800  0.93300  -18.97400 1.000 36.21332  ? 3   GLN   H CA  1 
ATOM   19   C  C   . GLN   A 1 3   ? -3.19600  2.15100  -19.75100 1.000 38.71927  ? 3   GLN   H C   1 
ATOM   20   O  O   . GLN   A 1 3   ? -2.99300  2.08500  -20.96700 1.000 33.59174  ? 3   GLN   H O   1 
ATOM   21   C  CB  . GLN   A 1 3   ? -2.47100  0.02500  -18.66300 1.000 36.38578  ? 3   GLN   H CB  1 
ATOM   22   C  CG  . GLN   A 1 3   ? -2.85900  -1.38600 -18.26500 1.000 42.40658  ? 3   GLN   H CG  1 
ATOM   23   C  CD  . GLN   A 1 3   ? -1.69600  -2.19000 -17.74000 1.000 44.49520  ? 3   GLN   H CD  1 
ATOM   24   O  OE1 . GLN   A 1 3   ? -1.07900  -1.82900 -16.73900 1.000 44.65475  ? 3   GLN   H OE1 1 
ATOM   25   N  NE2 . GLN   A 1 3   ? -1.38900  -3.29200 -18.41400 1.000 40.68075  ? 3   GLN   H NE2 1 
ATOM   26   N  N   . LEU   A 1 4   ? -3.03200  3.26200  -19.03500 1.000 38.76936  ? 4   LEU   H N   1 
ATOM   27   C  CA  . LEU   A 1 4   ? -2.39000  4.46700  -19.54400 1.000 33.62030  ? 4   LEU   H CA  1 
ATOM   28   C  C   . LEU   A 1 4   ? -1.30000  4.86000  -18.55900 1.000 39.97956  ? 4   LEU   H C   1 
ATOM   29   O  O   . LEU   A 1 4   ? -1.54600  4.90400  -17.34900 1.000 42.90659  ? 4   LEU   H O   1 
ATOM   30   C  CB  . LEU   A 1 4   ? -3.38700  5.62200  -19.70700 1.000 31.43324  ? 4   LEU   H CB  1 
ATOM   31   C  CG  . LEU   A 1 4   ? -4.78300  5.33600  -20.26500 1.000 30.85009  ? 4   LEU   H CG  1 
ATOM   32   C  CD1 . LEU   A 1 4   ? -5.68900  6.53500  -20.04900 1.000 32.60497  ? 4   LEU   H CD1 1 
ATOM   33   C  CD2 . LEU   A 1 4   ? -4.72400  4.98200  -21.73900 1.000 35.85033  ? 4   LEU   H CD2 1 
ATOM   34   N  N   . VAL   A 1 5   ? -0.09700  5.13000  -19.06400 1.000 39.55469  ? 5   VAL   H N   1 
ATOM   35   C  CA  . VAL   A 1 5   ? 1.04700   5.46700  -18.22000 1.000 40.02023  ? 5   VAL   H CA  1 
ATOM   36   C  C   . VAL   A 1 5   ? 1.73300   6.69400  -18.79900 1.000 42.23404  ? 5   VAL   H C   1 
ATOM   37   O  O   . VAL   A 1 5   ? 2.20100   6.66300  -19.94300 1.000 47.53063  ? 5   VAL   H O   1 
ATOM   38   C  CB  . VAL   A 1 5   ? 2.05200   4.30700  -18.10200 1.000 42.51166  ? 5   VAL   H CB  1 
ATOM   39   C  CG1 . VAL   A 1 5   ? 2.94300   4.50400  -16.88500 1.000 45.72842  ? 5   VAL   H CG1 1 
ATOM   40   C  CG2 . VAL   A 1 5   ? 1.33900   2.96600  -18.03500 1.000 37.06893  ? 5   VAL   H CG2 1 
ATOM   41   N  N   . GLU   A 1 6   ? 1.81400   7.75900  -18.00700 1.000 37.99480  ? 6   GLU   H N   1 
ATOM   42   C  CA  . GLU   A 1 6   ? 2.49700   8.97700  -18.41400 1.000 35.91704  ? 6   GLU   H CA  1 
ATOM   43   C  C   . GLU   A 1 6   ? 3.96100   8.94100  -17.99200 1.000 35.40161  ? 6   GLU   H C   1 
ATOM   44   O  O   . GLU   A 1 6   ? 4.33700   8.26200  -17.03300 1.000 39.53409  ? 6   GLU   H O   1 
ATOM   45   C  CB  . GLU   A 1 6   ? 1.82600   10.21100 -17.80700 1.000 35.49973  ? 6   GLU   H CB  1 
ATOM   46   C  CG  . GLU   A 1 6   ? 0.40000   10.44200 -18.26200 1.000 36.50740  ? 6   GLU   H CG  1 
ATOM   47   C  CD  . GLU   A 1 6   ? -0.61100  9.72000  -17.39500 1.000 38.32664  ? 6   GLU   H CD  1 
ATOM   48   O  OE1 . GLU   A 1 6   ? -0.20200  8.84100  -16.60900 1.000 40.65575  ? 6   GLU   H OE1 1 
ATOM   49   O  OE2 . GLU   A 1 6   ? -1.81400  10.03600 -17.49500 1.000 37.43759  ? 6   GLU   H OE2 1 
ATOM   50   N  N   . SER   A 1 7   ? 4.78700   9.69000  -18.72000 1.000 38.75120  ? 7   SER   H N   1 
ATOM   51   C  CA  . SER   A 1 7   ? 6.19600   9.83400  -18.38400 1.000 37.52605  ? 7   SER   H CA  1 
ATOM   52   C  C   . SER   A 1 7   ? 6.67700   11.18900 -18.88200 1.000 39.65326  ? 7   SER   H C   1 
ATOM   53   O  O   . SER   A 1 7   ? 6.03000   11.83800 -19.70800 1.000 31.82177  ? 7   SER   H O   1 
ATOM   54   C  CB  . SER   A 1 7   ? 7.03900   8.70200  -18.98300 1.000 36.28247  ? 7   SER   H CB  1 
ATOM   55   O  OG  . SER   A 1 7   ? 7.09500   8.79500  -20.39600 1.000 37.60955  ? 7   SER   H OG  1 
ATOM   56   N  N   . GLY   A 1 8   ? 7.82500   11.61700 -18.36300 1.000 34.50753  ? 8   GLY   H N   1 
ATOM   57   C  CA  . GLY   A 1 8   ? 8.46500   12.82800 -18.82700 1.000 36.60676  ? 8   GLY   H CA  1 
ATOM   58   C  C   . GLY   A 1 8   ? 8.29500   14.04700 -17.94800 1.000 41.81347  ? 8   GLY   H C   1 
ATOM   59   O  O   . GLY   A 1 8   ? 8.78800   15.12000 -18.31300 1.000 45.13214  ? 8   GLY   H O   1 
ATOM   60   N  N   . GLY   A 1 9   ? 7.61600   13.92800 -16.81300 1.000 35.28252  ? 9   GLY   H N   1 
ATOM   61   C  CA  . GLY   A 1 9   ? 7.48100   15.04400 -15.90200 1.000 38.88868  ? 9   GLY   H CA  1 
ATOM   62   C  C   . GLY   A 1 9   ? 8.78800   15.35100 -15.19300 1.000 44.59789  ? 9   GLY   H C   1 
ATOM   63   O  O   . GLY   A 1 9   ? 9.79400   14.65300 -15.32600 1.000 57.62267  ? 9   GLY   H O   1 
ATOM   64   N  N   . GLY   A 1 10  ? 8.76800   16.42800 -14.42400 1.000 43.02420  ? 10  GLY   H N   1 
ATOM   65   C  CA  . GLY   A 1 10  ? 9.92000   16.81100 -13.63600 1.000 48.47406  ? 10  GLY   H CA  1 
ATOM   66   C  C   . GLY   A 1 10  ? 10.01800  18.31700 -13.50000 1.000 43.18191  ? 10  GLY   H C   1 
ATOM   67   O  O   . GLY   A 1 10  ? 9.09400   19.05400 -13.83400 1.000 37.47165  ? 10  GLY   H O   1 
ATOM   68   N  N   . LEU   A 1 11  ? 11.17100  18.75600 -12.99800 1.000 39.96246  ? 11  LEU   H N   1 
ATOM   69   C  CA  . LEU   A 1 11  ? 11.42400  20.16700 -12.73400 1.000 45.14127  ? 11  LEU   H CA  1 
ATOM   70   C  C   . LEU   A 1 11  ? 12.02300  20.83500 -13.96600 1.000 46.76789  ? 11  LEU   H C   1 
ATOM   71   O  O   . LEU   A 1 11  ? 12.98900  20.33300 -14.54900 1.000 48.43751  ? 11  LEU   H O   1 
ATOM   72   C  CB  . LEU   A 1 11  ? 12.35700  20.33100 -11.53200 1.000 42.80887  ? 11  LEU   H CB  1 
ATOM   73   C  CG  . LEU   A 1 11  ? 12.76500  21.76000 -11.17100 1.000 41.49554  ? 11  LEU   H CG  1 
ATOM   74   C  CD1 . LEU   A 1 11  ? 11.51100  22.64100 -11.05700 1.000 41.54361  ? 11  LEU   H CD1 1 
ATOM   75   C  CD2 . LEU   A 1 11  ? 13.59500  21.78800 -9.88600  1.000 39.38781  ? 11  LEU   H CD2 1 
ATOM   76   N  N   . VAL   A 1 12  ? 11.45000  21.97300 -14.35000 1.000 39.96873  ? 12  VAL   H N   1 
ATOM   77   C  CA  . VAL   A 1 12  ? 11.90100  22.73200 -15.50900 1.000 43.65214  ? 12  VAL   H CA  1 
ATOM   78   C  C   . VAL   A 1 12  ? 11.85600  24.21500 -15.16300 1.000 46.50029  ? 12  VAL   H C   1 
ATOM   79   O  O   . VAL   A 1 12  ? 10.95700  24.67400 -14.45000 1.000 43.64455  ? 12  VAL   H O   1 
ATOM   80   C  CB  . VAL   A 1 12  ? 11.04900  22.40700 -16.75600 1.000 40.63362  ? 12  VAL   H CB  1 
ATOM   81   C  CG1 . VAL   A 1 12  ? 9.65000   22.99100 -16.62900 1.000 43.43051  ? 12  VAL   H CG1 1 
ATOM   82   C  CG2 . VAL   A 1 12  ? 11.73600  22.90100 -18.01700 1.000 42.56842  ? 12  VAL   H CG2 1 
ATOM   83   N  N   . THR   A 1 13  ? 12.84600  24.96000 -15.64900 1.000 47.22214  ? 13  THR   H N   1 
ATOM   84   C  CA  . THR   A 1 13  ? 12.92100  26.38400 -15.37300 1.000 45.17919  ? 13  THR   H CA  1 
ATOM   85   C  C   . THR   A 1 13  ? 11.91000  27.14900 -16.22700 1.000 44.25821  ? 13  THR   H C   1 
ATOM   86   O  O   . THR   A 1 13  ? 11.54200  26.69900 -17.31600 1.000 45.88352  ? 13  THR   H O   1 
ATOM   87   C  CB  . THR   A 1 13  ? 14.32900  26.90500 -15.64800 1.000 45.71150  ? 13  THR   H CB  1 
ATOM   88   O  OG1 . THR   A 1 13  ? 14.68400  26.63000 -17.00800 1.000 49.12845  ? 13  THR   H OG1 1 
ATOM   89   C  CG2 . THR   A 1 13  ? 15.33600  26.23600 -14.72000 1.000 45.18518  ? 13  THR   H CG2 1 
ATOM   90   N  N   . PRO   A 1 14  ? 11.43800  28.30300 -15.74700 1.000 38.67099  ? 14  PRO   H N   1 
ATOM   91   C  CA  . PRO   A 1 14  ? 10.45800  29.07500 -16.52200 1.000 39.96271  ? 14  PRO   H CA  1 
ATOM   92   C  C   . PRO   A 1 14  ? 11.01000  29.46500 -17.88500 1.000 43.24654  ? 14  PRO   H C   1 
ATOM   93   O  O   . PRO   A 1 14  ? 12.17000  29.85900 -18.02000 1.000 39.54315  ? 14  PRO   H O   1 
ATOM   94   C  CB  . PRO   A 1 14  ? 10.19700  30.30400 -15.64400 1.000 37.36939  ? 14  PRO   H CB  1 
ATOM   95   C  CG  . PRO   A 1 14  ? 10.58500  29.88300 -14.27100 1.000 39.17836  ? 14  PRO   H CG  1 
ATOM   96   C  CD  . PRO   A 1 14  ? 11.71900  28.92100 -14.44000 1.000 46.24996  ? 14  PRO   H CD  1 
ATOM   97   N  N   . GLY   A 1 15  ? 10.15500  29.34900 -18.90000 1.000 42.28900  ? 15  GLY   H N   1 
ATOM   98   C  CA  . GLY   A 1 15  ? 10.55700  29.51300 -20.27600 1.000 41.40215  ? 15  GLY   H CA  1 
ATOM   99   C  C   . GLY   A 1 15  ? 11.05900  28.24900 -20.93900 1.000 42.30817  ? 15  GLY   H C   1 
ATOM   100  O  O   . GLY   A 1 15  ? 11.09500  28.18400 -22.17300 1.000 40.34758  ? 15  GLY   H O   1 
ATOM   101  N  N   . GLY   A 1 16  ? 11.43500  27.24200 -20.15600 1.000 44.35140  ? 16  GLY   H N   1 
ATOM   102  C  CA  . GLY   A 1 16  ? 11.95700  26.00700 -20.69500 1.000 47.84080  ? 16  GLY   H CA  1 
ATOM   103  C  C   . GLY   A 1 16  ? 10.88900  25.15900 -21.36200 1.000 43.38254  ? 16  GLY   H C   1 
ATOM   104  O  O   . GLY   A 1 16  ? 9.71300   25.51400 -21.45000 1.000 44.26145  ? 16  GLY   H O   1 
ATOM   105  N  N   . SER   A 1 17  ? 11.32700  23.99700 -21.84100 1.000 43.83113  ? 17  SER   H N   1 
ATOM   106  C  CA  . SER   A 1 17  ? 10.47900  23.08300 -22.58900 1.000 36.82102  ? 17  SER   H CA  1 
ATOM   107  C  C   . SER   A 1 17  ? 10.58800  21.67700 -22.01700 1.000 32.97825  ? 17  SER   H C   1 
ATOM   108  O  O   . SER   A 1 17  ? 11.61700  21.29500 -21.45400 1.000 35.70793  ? 17  SER   H O   1 
ATOM   109  C  CB  . SER   A 1 17  ? 10.84800  23.07400 -24.08000 1.000 38.45844  ? 17  SER   H CB  1 
ATOM   110  O  OG  . SER   A 1 17  ? 10.86100  24.38900 -24.60900 1.000 56.22790  ? 17  SER   H OG  1 
ATOM   111  N  N   . LEU   A 1 18  ? 9.50900   20.91100 -22.17200 1.000 37.81549  ? 18  LEU   H N   1 
ATOM   112  C  CA  . LEU   A 1 18  ? 9.43500   19.55200 -21.65400 1.000 38.38204  ? 18  LEU   H CA  1 
ATOM   113  C  C   . LEU   A 1 18  ? 8.47900   18.74600 -22.52200 1.000 35.58711  ? 18  LEU   H C   1 
ATOM   114  O  O   . LEU   A 1 18  ? 7.43300   19.25200 -22.93600 1.000 34.98972  ? 18  LEU   H O   1 
ATOM   115  C  CB  . LEU   A 1 18  ? 8.97100   19.54200 -20.19300 1.000 36.84522  ? 18  LEU   H CB  1 
ATOM   116  C  CG  . LEU   A 1 18  ? 9.40400   18.37800 -19.30200 1.000 33.69070  ? 18  LEU   H CG  1 
ATOM   117  C  CD1 . LEU   A 1 18  ? 10.86100  18.52700 -18.90000 1.000 37.91211  ? 18  LEU   H CD1 1 
ATOM   118  C  CD2 . LEU   A 1 18  ? 8.51500   18.31000 -18.07300 1.000 35.82204  ? 18  LEU   H CD2 1 
ATOM   119  N  N   . ARG   A 1 19  ? 8.84400   17.49500 -22.79200 1.000 34.14622  ? 19  ARG   H N   1 
ATOM   120  C  CA  . ARG   A 1 19  ? 8.05700   16.60700 -23.63900 1.000 32.37985  ? 19  ARG   H CA  1 
ATOM   121  C  C   . ARG   A 1 19  ? 7.46700   15.49300 -22.78800 1.000 30.66677  ? 19  ARG   H C   1 
ATOM   122  O  O   . ARG   A 1 19  ? 8.20700   14.73300 -22.15300 1.000 37.00453  ? 19  ARG   H O   1 
ATOM   123  C  CB  . ARG   A 1 19  ? 8.91000   16.02300 -24.76400 1.000 36.64996  ? 19  ARG   H CB  1 
ATOM   124  C  CG  . ARG   A 1 19  ? 8.12800   15.21300 -25.78700 1.000 31.60924  ? 19  ARG   H CG  1 
ATOM   125  C  CD  . ARG   A 1 19  ? 9.04500   14.69200 -26.88100 1.000 34.97694  ? 19  ARG   H CD  1 
ATOM   126  N  NE  . ARG   A 1 19  ? 8.30700   14.06600 -27.97300 1.000 43.23610  ? 19  ARG   H NE  1 
ATOM   127  C  CZ  . ARG   A 1 19  ? 8.19800   12.75200 -28.14600 1.000 43.02152  ? 19  ARG   H CZ  1 
ATOM   128  N  NH1 . ARG   A 1 19  ? 7.50700   12.27400 -29.17200 1.000 44.67638  ? 19  ARG   H NH1 1 
ATOM   129  N  NH2 . ARG   A 1 19  ? 8.77900   11.91700 -27.29600 1.000 39.14908  ? 19  ARG   H NH2 1 
ATOM   130  N  N   . LEU   A 1 20  ? 6.14100   15.39200 -22.78800 1.000 31.87978  ? 20  LEU   H N   1 
ATOM   131  C  CA  . LEU   A 1 20  ? 5.43100   14.36600 -22.03900 1.000 35.73438  ? 20  LEU   H CA  1 
ATOM   132  C  C   . LEU   A 1 20  ? 5.01300   13.22600 -22.95700 1.000 31.12244  ? 20  LEU   H C   1 
ATOM   133  O  O   . LEU   A 1 20  ? 4.62800   13.44600 -24.10900 1.000 36.89643  ? 20  LEU   H O   1 
ATOM   134  C  CB  . LEU   A 1 20  ? 4.19500   14.94100 -21.34500 1.000 32.34862  ? 20  LEU   H CB  1 
ATOM   135  C  CG  . LEU   A 1 20  ? 4.42100   16.01500 -20.28000 1.000 31.08550  ? 20  LEU   H CG  1 
ATOM   136  C  CD1 . LEU   A 1 20  ? 3.25600   16.03800 -19.31700 1.000 29.66809  ? 20  LEU   H CD1 1 
ATOM   137  C  CD2 . LEU   A 1 20  ? 5.72000   15.79500 -19.52600 1.000 30.40055  ? 20  LEU   H CD2 1 
ATOM   138  N  N   . SER   A 1 21  ? 5.08900   12.00600 -22.43300 1.000 34.01436  ? 21  SER   H N   1 
ATOM   139  C  CA  . SER   A 1 21  ? 4.70200   10.80600 -23.15600 1.000 39.40119  ? 21  SER   H CA  1 
ATOM   140  C  C   . SER   A 1 21  ? 3.66000   10.04600 -22.35000 1.000 35.68596  ? 21  SER   H C   1 
ATOM   141  O  O   . SER   A 1 21  ? 3.65400   10.08800 -21.11700 1.000 35.33353  ? 21  SER   H O   1 
ATOM   142  C  CB  . SER   A 1 21  ? 5.90500   9.88800  -23.41300 1.000 31.31481  ? 21  SER   H CB  1 
ATOM   143  O  OG  . SER   A 1 21  ? 6.64000   10.28000 -24.55900 1.000 42.08610  ? 21  SER   H OG  1 
ATOM   144  N  N   . CYS   A 1 22  ? 2.77300   9.35300  -23.05700 1.000 34.75178  ? 22  CYS   H N   1 
ATOM   145  C  CA  . CYS   A 1 22  ? 1.78200   8.48600  -22.42300 1.000 37.67155  ? 22  CYS   H CA  1 
ATOM   146  C  C   . CYS   A 1 22  ? 1.59300   7.24700  -23.28400 1.000 38.73342  ? 22  CYS   H C   1 
ATOM   147  O  O   . CYS   A 1 22  ? 1.07400   7.34100  -24.39900 1.000 39.29366  ? 22  CYS   H O   1 
ATOM   148  C  CB  . CYS   A 1 22  ? 0.44500   9.20100  -22.22700 1.000 38.66450  ? 22  CYS   H CB  1 
ATOM   149  S  SG  . CYS   A 1 22  ? -0.96800  8.04800  -22.10000 1.000 48.10557  ? 22  CYS   H SG  1 
ATOM   150  N  N   . ALA   A 1 23  ? 1.99400   6.09300  -22.77000 1.000 37.71585  ? 23  ALA   H N   1 
ATOM   151  C  CA  . ALA   A 1 23  ? 1.77800   4.83400  -23.46400 1.000 38.00052  ? 23  ALA   H CA  1 
ATOM   152  C  C   . ALA   A 1 23  ? 0.46600   4.19900  -23.01300 1.000 37.57928  ? 23  ALA   H C   1 
ATOM   153  O  O   . ALA   A 1 23  ? 0.04900   4.34600  -21.86200 1.000 36.54033  ? 23  ALA   H O   1 
ATOM   154  C  CB  . ALA   A 1 23  ? 2.94500   3.88100  -23.21300 1.000 45.82264  ? 23  ALA   H CB  1 
ATOM   155  N  N   . ALA   A 1 24  ? -0.19000  3.49500  -23.93400 1.000 29.84376  ? 24  ALA   H N   1 
ATOM   156  C  CA  . ALA   A 1 24  ? -1.52300  2.97700  -23.67800 1.000 30.20229  ? 24  ALA   H CA  1 
ATOM   157  C  C   . ALA   A 1 24  ? -1.61100  1.52000  -24.10100 1.000 33.40853  ? 24  ALA   H C   1 
ATOM   158  O  O   . ALA   A 1 24  ? -0.93600  1.08400  -25.04000 1.000 29.26517  ? 24  ALA   H O   1 
ATOM   159  C  CB  . ALA   A 1 24  ? -2.58300  3.79800  -24.41500 1.000 31.82661  ? 24  ALA   H CB  1 
ATOM   160  N  N   . SER   A 1 25  ? -2.48100  0.78200  -23.41700 1.000 36.98691  ? 25  SER   H N   1 
ATOM   161  C  CA  . SER   A 1 25  ? -2.67000  -0.62400 -23.72200 1.000 30.53659  ? 25  SER   H CA  1 
ATOM   162  C  C   . SER   A 1 25  ? -4.10400  -1.02600 -23.41700 1.000 31.72586  ? 25  SER   H C   1 
ATOM   163  O  O   . SER   A 1 25  ? -4.83800  -0.32400 -22.71300 1.000 34.52496  ? 25  SER   H O   1 
ATOM   164  C  CB  . SER   A 1 25  ? -1.70600  -1.50000 -22.92000 1.000 35.94214  ? 25  SER   H CB  1 
ATOM   165  O  OG  . SER   A 1 25  ? -1.59100  -1.02200 -21.58900 1.000 41.99735  ? 25  SER   H OG  1 
ATOM   166  N  N   . GLY   A 1 26  ? -4.48300  -2.18800 -23.94000 1.000 35.93004  ? 26  GLY   H N   1 
ATOM   167  C  CA  . GLY   A 1 26  ? -5.73400  -2.81200 -23.57900 1.000 31.37897  ? 26  GLY   H CA  1 
ATOM   168  C  C   . GLY   A 1 26  ? -6.93700  -2.39700 -24.39000 1.000 34.59929  ? 26  GLY   H C   1 
ATOM   169  O  O   . GLY   A 1 26  ? -8.06200  -2.74400 -24.01100 1.000 28.99584  ? 26  GLY   H O   1 
ATOM   170  N  N   . PHE   A 1 27  ? -6.74800  -1.68000 -25.49500 1.000 34.56436  ? 27  PHE   H N   1 
ATOM   171  C  CA  . PHE   A 1 27  ? -7.87100  -1.29100 -26.33700 1.000 30.83909  ? 27  PHE   H CA  1 
ATOM   172  C  C   . PHE   A 1 27  ? -7.35300  -0.95700 -27.72800 1.000 32.90863  ? 27  PHE   H C   1 
ATOM   173  O  O   . PHE   A 1 27  ? -6.15000  -0.78700 -27.94300 1.000 28.93511  ? 27  PHE   H O   1 
ATOM   174  C  CB  . PHE   A 1 27  ? -8.64300  -0.11200 -25.73300 1.000 31.70513  ? 27  PHE   H CB  1 
ATOM   175  C  CG  . PHE   A 1 27  ? -7.81700  1.12400  -25.53700 1.000 28.79768  ? 27  PHE   H CG  1 
ATOM   176  C  CD1 . PHE   A 1 27  ? -7.07000  1.29700  -24.38500 1.000 32.99905  ? 27  PHE   H CD1 1 
ATOM   177  C  CD2 . PHE   A 1 27  ? -7.79900  2.12100  -26.49800 1.000 34.27047  ? 27  PHE   H CD2 1 
ATOM   178  C  CE1 . PHE   A 1 27  ? -6.31300  2.43800  -24.19700 1.000 35.70513  ? 27  PHE   H CE1 1 
ATOM   179  C  CE2 . PHE   A 1 27  ? -7.04300  3.26500  -26.31700 1.000 36.83016  ? 27  PHE   H CE2 1 
ATOM   180  C  CZ  . PHE   A 1 27  ? -6.30000  3.42300  -25.16400 1.000 35.30849  ? 27  PHE   H CZ  1 
ATOM   181  N  N   . THR   A 1 28  ? -8.28200  -0.87600 -28.68000 1.000 32.39125  ? 28  THR   H N   1 
ATOM   182  C  CA  . THR   A 1 28  ? -7.92100  -0.48600 -30.03700 1.000 33.32635  ? 28  THR   H CA  1 
ATOM   183  C  C   . THR   A 1 28  ? -7.56900  0.99500  -30.06200 1.000 31.56353  ? 28  THR   H C   1 
ATOM   184  O  O   . THR   A 1 28  ? -8.43900  1.84900  -30.25800 1.000 34.27668  ? 28  THR   H O   1 
ATOM   185  C  CB  . THR   A 1 28  ? -9.05100  -0.79400 -31.02000 1.000 36.11298  ? 28  THR   H CB  1 
ATOM   186  O  OG1 . THR   A 1 28  ? -10.31700 -0.52900 -30.40300 1.000 41.75601  ? 28  THR   H OG1 1 
ATOM   187  C  CG2 . THR   A 1 28  ? -8.99500  -2.25100 -31.45100 1.000 34.99300  ? 28  THR   H CG2 1 
ATOM   188  N  N   . PHE   A 1 29  ? -6.28000  1.28700  -29.87100 1.000 32.10948  ? 29  PHE   H N   1 
ATOM   189  C  CA  . PHE   A 1 29  ? -5.81800  2.65800  -29.67400 1.000 30.83237  ? 29  PHE   H CA  1 
ATOM   190  C  C   . PHE   A 1 29  ? -6.19500  3.55900  -30.84400 1.000 34.53163  ? 29  PHE   H C   1 
ATOM   191  O  O   . PHE   A 1 29  ? -6.57100  4.72000  -30.64600 1.000 35.05980  ? 29  PHE   H O   1 
ATOM   192  C  CB  . PHE   A 1 29  ? -4.30500  2.64500  -29.46800 1.000 30.01386  ? 29  PHE   H CB  1 
ATOM   193  C  CG  . PHE   A 1 29  ? -3.71300  3.98000  -29.12300 1.000 35.49354  ? 29  PHE   H CG  1 
ATOM   194  C  CD1 . PHE   A 1 29  ? -3.77100  4.46700  -27.82700 1.000 39.27822  ? 29  PHE   H CD1 1 
ATOM   195  C  CD2 . PHE   A 1 29  ? -3.06200  4.73100  -30.08600 1.000 30.37652  ? 29  PHE   H CD2 1 
ATOM   196  C  CE1 . PHE   A 1 29  ? -3.20800  5.68700  -27.50500 1.000 34.91372  ? 29  PHE   H CE1 1 
ATOM   197  C  CE2 . PHE   A 1 29  ? -2.49800  5.95200  -29.77000 1.000 33.49400  ? 29  PHE   H CE2 1 
ATOM   198  C  CZ  . PHE   A 1 29  ? -2.57100  6.43100  -28.47800 1.000 35.52207  ? 29  PHE   H CZ  1 
ATOM   199  N  N   . ASN   A 1 30  ? -6.10700  3.04200  -32.07000 1.000 32.86126  ? 30  ASN   H N   1 
ATOM   200  C  CA  . ASN   A 1 30  ? -6.29100  3.85000  -33.27100 1.000 32.02977  ? 30  ASN   H CA  1 
ATOM   201  C  C   . ASN   A 1 30  ? -7.74500  4.21300  -33.54800 1.000 30.75531  ? 30  ASN   H C   1 
ATOM   202  O  O   . ASN   A 1 30  ? -8.01900  4.83000  -34.58300 1.000 35.66604  ? 30  ASN   H O   1 
ATOM   203  C  CB  . ASN   A 1 30  ? -5.71000  3.11600  -34.47600 1.000 38.07031  ? 30  ASN   H CB  1 
ATOM   204  C  CG  . ASN   A 1 30  ? -6.34100  1.75600  -34.68100 1.000 35.14563  ? 30  ASN   H CG  1 
ATOM   205  O  OD1 . ASN   A 1 30  ? -6.12800  0.83700  -33.89000 1.000 35.42735  ? 30  ASN   H OD1 1 
ATOM   206  N  ND2 . ASN   A 1 30  ? -7.13200  1.62300  -35.73800 1.000 29.30501  ? 30  ASN   H ND2 1 
ATOM   207  N  N   . THR   A 1 31  ? -8.68100  3.84300  -32.67500 1.000 25.63822  ? 31  THR   H N   1 
ATOM   208  C  CA  . THR   A 1 31  ? -10.07900 4.22600  -32.81800 1.000 32.52979  ? 31  THR   H CA  1 
ATOM   209  C  C   . THR   A 1 31  ? -10.52500 5.16800  -31.70500 1.000 34.35758  ? 31  THR   H C   1 
ATOM   210  O  O   . THR   A 1 31  ? -11.72600 5.30100  -31.44900 1.000 33.10688  ? 31  THR   H O   1 
ATOM   211  C  CB  . THR   A 1 31  ? -10.97400 2.98500  -32.84700 1.000 32.22638  ? 31  THR   H CB  1 
ATOM   212  O  OG1 . THR   A 1 31  ? -11.32600 2.61900  -31.50700 1.000 30.68060  ? 31  THR   H OG1 1 
ATOM   213  C  CG2 . THR   A 1 31  ? -10.25200 1.81900  -33.50800 1.000 31.76375  ? 31  THR   H CG2 1 
ATOM   214  N  N   . TYR   A 1 32  ? -9.57900  5.82700  -31.04100 1.000 32.79796  ? 32  TYR   H N   1 
ATOM   215  C  CA  . TYR   A 1 32  ? -9.86800  6.59800  -29.84100 1.000 34.59413  ? 32  TYR   H CA  1 
ATOM   216  C  C   . TYR   A 1 32  ? -9.19600  7.95900  -29.90300 1.000 36.16034  ? 32  TYR   H C   1 
ATOM   217  O  O   . TYR   A 1 32  ? -8.02300  8.06500  -30.27600 1.000 33.75248  ? 32  TYR   H O   1 
ATOM   218  C  CB  . TYR   A 1 32  ? -9.39900  5.85500  -28.59000 1.000 33.99939  ? 32  TYR   H CB  1 
ATOM   219  C  CG  . TYR   A 1 32  ? -10.43200 4.91900  -28.02800 1.000 38.77655  ? 32  TYR   H CG  1 
ATOM   220  C  CD1 . TYR   A 1 32  ? -11.41300 5.38200  -27.16400 1.000 37.55515  ? 32  TYR   H CD1 1 
ATOM   221  C  CD2 . TYR   A 1 32  ? -10.43300 3.57400  -28.36700 1.000 34.81772  ? 32  TYR   H CD2 1 
ATOM   222  C  CE1 . TYR   A 1 32  ? -12.36100 4.53200  -26.65000 1.000 39.55399  ? 32  TYR   H CE1 1 
ATOM   223  C  CE2 . TYR   A 1 32  ? -11.37700 2.71600  -27.85800 1.000 31.37611  ? 32  TYR   H CE2 1 
ATOM   224  C  CZ  . TYR   A 1 32  ? -12.33800 3.20200  -27.00000 1.000 36.70377  ? 32  TYR   H CZ  1 
ATOM   225  O  OH  . TYR   A 1 32  ? -13.28500 2.36000  -26.48500 1.000 44.55876  ? 32  TYR   H OH  1 
ATOM   226  N  N   . SER   A 1 33  ? -9.93800  8.99200  -29.52200 1.000 34.28164  ? 33  SER   H N   1 
ATOM   227  C  CA  . SER   A 1 33  ? -9.32100  10.27700 -29.24100 1.000 30.61764  ? 33  SER   H CA  1 
ATOM   228  C  C   . SER   A 1 33  ? -8.55800  10.18800 -27.92800 1.000 33.99694  ? 33  SER   H C   1 
ATOM   229  O  O   . SER   A 1 33  ? -9.09700  9.72800  -26.91600 1.000 39.92898  ? 33  SER   H O   1 
ATOM   230  C  CB  . SER   A 1 33  ? -10.37700 11.37700 -29.16800 1.000 29.90326  ? 33  SER   H CB  1 
ATOM   231  O  OG  . SER   A 1 33  ? -11.34500 11.09400 -28.17400 1.000 34.91695  ? 33  SER   H OG  1 
ATOM   232  N  N   . MET   A 1 34  ? -7.29900  10.60800 -27.94500 1.000 30.05720  ? 34  MET   H N   1 
ATOM   233  C  CA  . MET   A 1 34  ? -6.48900  10.66000 -26.73900 1.000 28.41320  ? 34  MET   H CA  1 
ATOM   234  C  C   . MET   A 1 34  ? -6.42000  12.09200 -26.22800 1.000 34.49390  ? 34  MET   H C   1 
ATOM   235  O  O   . MET   A 1 34  ? -6.41000  13.04900 -27.00600 1.000 36.58285  ? 34  MET   H O   1 
ATOM   236  C  CB  . MET   A 1 34  ? -5.08400  10.11400 -26.99400 1.000 30.42073  ? 34  MET   H CB  1 
ATOM   237  C  CG  . MET   A 1 34  ? -5.05600  8.60800  -27.16600 1.000 40.67460  ? 34  MET   H CG  1 
ATOM   238  S  SD  . MET   A 1 34  ? -5.90200  7.74500  -25.82600 1.000 36.84137  ? 34  MET   H SD  1 
ATOM   239  C  CE  . MET   A 1 34  ? -4.78200  8.04800  -24.46600 1.000 28.43131  ? 34  MET   H CE  1 
ATOM   240  N  N   . ASN   A 1 35  ? -6.38400  12.23300 -24.90500 1.000 35.36927  ? 35  ASN   H N   1 
ATOM   241  C  CA  . ASN   A 1 35  ? -6.60200  13.52800 -24.28100 1.000 28.29362  ? 35  ASN   H CA  1 
ATOM   242  C  C   . ASN   A 1 35  ? -5.62000  13.75000 -23.14300 1.000 34.31501  ? 35  ASN   H C   1 
ATOM   243  O  O   . ASN   A 1 35  ? -5.26700  12.81400 -22.42000 1.000 38.94092  ? 35  ASN   H O   1 
ATOM   244  C  CB  . ASN   A 1 35  ? -8.03700  13.63800 -23.75700 1.000 29.94386  ? 35  ASN   H CB  1 
ATOM   245  C  CG  . ASN   A 1 35  ? -9.05000  13.04500 -24.71600 1.000 33.42828  ? 35  ASN   H CG  1 
ATOM   246  O  OD1 . ASN   A 1 35  ? -9.60300  13.74400 -25.56300 1.000 33.31413  ? 35  ASN   H OD1 1 
ATOM   247  N  ND2 . ASN   A 1 35  ? -9.29400  11.74500 -24.58800 1.000 34.37963  ? 35  ASN   H ND2 1 
ATOM   248  N  N   . TRP   A 1 36  ? -5.18900  14.99900 -22.99200 1.000 36.65810  ? 36  TRP   H N   1 
ATOM   249  C  CA  . TRP   A 1 36  ? -4.35000  15.43000 -21.88300 1.000 31.98794  ? 36  TRP   H CA  1 
ATOM   250  C  C   . TRP   A 1 36  ? -5.15800  16.34700 -20.97400 1.000 30.38150  ? 36  TRP   H C   1 
ATOM   251  O  O   . TRP   A 1 36  ? -5.81900  17.27500 -21.45200 1.000 33.50179  ? 36  TRP   H O   1 
ATOM   252  C  CB  . TRP   A 1 36  ? -3.10100  16.15800 -22.38500 1.000 32.52162  ? 36  TRP   H CB  1 
ATOM   253  C  CG  . TRP   A 1 36  ? -2.03700  15.25400 -22.92600 1.000 30.68144  ? 36  TRP   H CG  1 
ATOM   254  C  CD1 . TRP   A 1 36  ? -1.81100  14.94700 -24.23500 1.000 30.91963  ? 36  TRP   H CD1 1 
ATOM   255  C  CD2 . TRP   A 1 36  ? -1.04500  14.54800 -22.17100 1.000 31.18229  ? 36  TRP   H CD2 1 
ATOM   256  N  NE1 . TRP   A 1 36  ? -0.74300  14.08900 -24.34300 1.000 31.86881  ? 36  TRP   H NE1 1 
ATOM   257  C  CE2 . TRP   A 1 36  ? -0.25500  13.82800 -23.09000 1.000 30.07089  ? 36  TRP   H CE2 1 
ATOM   258  C  CE3 . TRP   A 1 36  ? -0.75000  14.45100 -20.80800 1.000 30.25534  ? 36  TRP   H CE3 1 
ATOM   259  C  CZ2 . TRP   A 1 36  ? 0.81000   13.02500 -22.69000 1.000 33.78101  ? 36  TRP   H CZ2 1 
ATOM   260  C  CZ3 . TRP   A 1 36  ? 0.30700   13.65300 -20.41300 1.000 28.55239  ? 36  TRP   H CZ3 1 
ATOM   261  C  CH2 . TRP   A 1 36  ? 1.07400   12.95100 -21.35000 1.000 33.01538  ? 36  TRP   H CH2 1 
ATOM   262  N  N   . VAL   A 1 37  ? -5.10700  16.08100 -19.67100 1.000 31.55897  ? 37  VAL   H N   1 
ATOM   263  C  CA  . VAL   A 1 37  ? -5.79200  16.88600 -18.66500 1.000 30.08573  ? 37  VAL   H CA  1 
ATOM   264  C  C   . VAL   A 1 37  ? -4.83400  17.09000 -17.50000 1.000 28.91469  ? 37  VAL   H C   1 
ATOM   265  O  O   . VAL   A 1 37  ? -4.11100  16.16800 -17.11300 1.000 32.33335  ? 37  VAL   H O   1 
ATOM   266  C  CB  . VAL   A 1 37  ? -7.10300  16.21600 -18.19400 1.000 27.59784  ? 37  VAL   H CB  1 
ATOM   267  C  CG1 . VAL   A 1 37  ? -7.71700  16.98700 -17.03900 1.000 28.22515  ? 37  VAL   H CG1 1 
ATOM   268  C  CG2 . VAL   A 1 37  ? -8.09400  16.10100 -19.34600 1.000 22.72734  ? 37  VAL   H CG2 1 
ATOM   269  N  N   . ARG   A 1 38  ? -4.81300  18.30000 -16.94600 1.000 30.32887  ? 38  ARG   H N   1 
ATOM   270  C  CA  . ARG   A 1 38  ? -3.88600  18.62200 -15.87300 1.000 32.93514  ? 38  ARG   H CA  1 
ATOM   271  C  C   . ARG   A 1 38  ? -4.63200  19.10500 -14.63600 1.000 33.05213  ? 38  ARG   H C   1 
ATOM   272  O  O   . ARG   A 1 38  ? -5.79500  19.51400 -14.69800 1.000 31.51258  ? 38  ARG   H O   1 
ATOM   273  C  CB  . ARG   A 1 38  ? -2.86400  19.67800 -16.31400 1.000 36.81949  ? 38  ARG   H CB  1 
ATOM   274  C  CG  . ARG   A 1 38  ? -3.39000  21.10300 -16.36800 1.000 33.98152  ? 38  ARG   H CG  1 
ATOM   275  C  CD  . ARG   A 1 38  ? -2.32000  22.03100 -16.92300 1.000 34.15050  ? 38  ARG   H CD  1 
ATOM   276  N  NE  . ARG   A 1 38  ? -2.84000  23.35300 -17.25400 1.000 36.35472  ? 38  ARG   H NE  1 
ATOM   277  C  CZ  . ARG   A 1 38  ? -2.09700  24.34400 -17.73400 1.000 35.07823  ? 38  ARG   H CZ  1 
ATOM   278  N  NH1 . ARG   A 1 38  ? -0.80000  24.16000 -17.94000 1.000 35.50637  ? 38  ARG   H NH1 1 
ATOM   279  N  NH2 . ARG   A 1 38  ? -2.64800  25.51800 -18.00800 1.000 34.73958  ? 38  ARG   H NH2 1 
ATOM   280  N  N   . GLN   A 1 39  ? -3.93400  19.04700 -13.50100 1.000 33.31771  ? 39  GLN   H N   1 
ATOM   281  C  CA  . GLN   A 1 39  ? -4.47900  19.46800 -12.21300 1.000 38.11498  ? 39  GLN   H CA  1 
ATOM   282  C  C   . GLN   A 1 39  ? -3.35600  20.10700 -11.40800 1.000 36.84139  ? 39  GLN   H C   1 
ATOM   283  O  O   . GLN   A 1 39  ? -2.45000  19.40900 -10.94300 1.000 31.65366  ? 39  GLN   H O   1 
ATOM   284  C  CB  . GLN   A 1 39  ? -5.08900  18.28900 -11.45500 1.000 31.93274  ? 39  GLN   H CB  1 
ATOM   285  C  CG  . GLN   A 1 39  ? -5.64200  18.65500 -10.08700 1.000 31.39905  ? 39  GLN   H CG  1 
ATOM   286  C  CD  . GLN   A 1 39  ? -6.57900  17.60100 -9.53100  1.000 36.83036  ? 39  GLN   H CD  1 
ATOM   287  O  OE1 . GLN   A 1 39  ? -6.37400  16.40300 -9.73200  1.000 36.96860  ? 39  GLN   H OE1 1 
ATOM   288  N  NE2 . GLN   A 1 39  ? -7.61700  18.04200 -8.82800  1.000 40.69825  ? 39  GLN   H NE2 1 
ATOM   289  N  N   . ALA   A 1 40  ? -3.41400  21.42700 -11.25000 1.000 41.25621  ? 40  ALA   H N   1 
ATOM   290  C  CA  . ALA   A 1 40  ? -2.42100  22.12800 -10.45500 1.000 36.20035  ? 40  ALA   H CA  1 
ATOM   291  C  C   . ALA   A 1 40  ? -2.53800  21.71900 -8.98700  1.000 41.01796  ? 40  ALA   H C   1 
ATOM   292  O  O   . ALA   A 1 40  ? -3.62000  21.34600 -8.52600  1.000 40.82196  ? 40  ALA   H O   1 
ATOM   293  C  CB  . ALA   A 1 40  ? -2.59400  23.63800 -10.59700 1.000 37.52224  ? 40  ALA   H CB  1 
ATOM   294  N  N   . PRO   A 1 41  ? -1.43700  21.76700 -8.23700  1.000 44.66315  ? 41  PRO   H N   1 
ATOM   295  C  CA  . PRO   A 1 41  ? -1.48100  21.33400 -6.83300  1.000 43.00607  ? 41  PRO   H CA  1 
ATOM   296  C  C   . PRO   A 1 41  ? -2.49200  22.13600 -6.02600  1.000 46.30893  ? 41  PRO   H C   1 
ATOM   297  O  O   . PRO   A 1 41  ? -2.45900  23.36900 -5.99900  1.000 46.82428  ? 41  PRO   H O   1 
ATOM   298  C  CB  . PRO   A 1 41  ? -0.04800  21.57100 -6.34400  1.000 44.66447  ? 41  PRO   H CB  1 
ATOM   299  C  CG  . PRO   A 1 41  ? 0.78500   21.53700 -7.57900  1.000 35.52517  ? 41  PRO   H CG  1 
ATOM   300  C  CD  . PRO   A 1 41  ? -0.07000  22.11900 -8.66400  1.000 42.07590  ? 41  PRO   H CD  1 
ATOM   301  N  N   . GLY   A 1 42  ? -3.40300  21.41700 -5.36800  1.000 41.37425  ? 42  GLY   H N   1 
ATOM   302  C  CA  . GLY   A 1 42  ? -4.43300  22.01500 -4.55200  1.000 40.31310  ? 42  GLY   H CA  1 
ATOM   303  C  C   . GLY   A 1 42  ? -5.68700  22.42300 -5.29600  1.000 45.40008  ? 42  GLY   H C   1 
ATOM   304  O  O   . GLY   A 1 42  ? -6.72800  22.62200 -4.66100  1.000 47.08621  ? 42  GLY   H O   1 
ATOM   305  N  N   . LYS   A 1 43  ? -5.62400  22.54000 -6.61900  1.000 47.37259  ? 43  LYS   H N   1 
ATOM   306  C  CA  . LYS   A 1 43  ? -6.71900  23.06900 -7.41200  1.000 42.09182  ? 43  LYS   H CA  1 
ATOM   307  C  C   . LYS   A 1 43  ? -7.48300  21.93600 -8.09900  1.000 42.04994  ? 43  LYS   H C   1 
ATOM   308  O  O   . LYS   A 1 43  ? -7.27300  20.75100 -7.82300  1.000 41.55683  ? 43  LYS   H O   1 
ATOM   309  C  CB  . LYS   A 1 43  ? -6.18000  24.08100 -8.42500  1.000 42.25455  ? 43  LYS   H CB  1 
ATOM   310  C  CG  . LYS   A 1 43  ? -5.55300  25.31200 -7.79300  1.000 49.57721  ? 43  LYS   H CG  1 
ATOM   311  C  CD  . LYS   A 1 43  ? -4.65400  26.04300 -8.77700  1.000 61.69347  ? 43  LYS   H CD  1 
ATOM   312  C  CE  . LYS   A 1 43  ? -3.53000  26.77500 -8.06000  1.000 60.67209  ? 43  LYS   H CE  1 
ATOM   313  N  NZ  . LYS   A 1 43  ? -2.24000  26.03300 -8.13800  1.000 57.69778  ? 43  LYS   H NZ  1 
ATOM   314  N  N   . GLY   A 1 44  ? -8.38600  22.30700 -9.00300  1.000 43.02757  ? 44  GLY   H N   1 
ATOM   315  C  CA  . GLY   A 1 44  ? -9.20000  21.35800 -9.73300  1.000 38.57575  ? 44  GLY   H CA  1 
ATOM   316  C  C   . GLY   A 1 44  ? -8.58400  20.96100 -11.05800 1.000 36.50505  ? 44  GLY   H C   1 
ATOM   317  O  O   . GLY   A 1 44  ? -7.38300  21.11400 -11.29100 1.000 35.55796  ? 44  GLY   H O   1 
ATOM   318  N  N   . LEU   A 1 45  ? -9.43300  20.44800 -11.94300 1.000 30.01844  ? 45  LEU   H N   1 
ATOM   319  C  CA  . LEU   A 1 45  ? -8.99500  19.89200 -13.21400 1.000 33.03228  ? 45  LEU   H CA  1 
ATOM   320  C  C   . LEU   A 1 45  ? -9.21000  20.88300 -14.35000 1.000 35.96494  ? 45  LEU   H C   1 
ATOM   321  O  O   . LEU   A 1 45  ? -10.16300 21.66700 -14.35000 1.000 38.12529  ? 45  LEU   H O   1 
ATOM   322  C  CB  . LEU   A 1 45  ? -9.73300  18.58600 -13.51300 1.000 36.63380  ? 45  LEU   H CB  1 
ATOM   323  C  CG  . LEU   A 1 45  ? -9.59300  17.51700 -12.42800 1.000 36.62733  ? 45  LEU   H CG  1 
ATOM   324  C  CD1 . LEU   A 1 45  ? -10.95400 16.97700 -12.01600 1.000 34.34701  ? 45  LEU   H CD1 1 
ATOM   325  C  CD2 . LEU   A 1 45  ? -8.68100  16.39700 -12.90000 1.000 32.13625  ? 45  LEU   H CD2 1 
ATOM   326  N  N   . GLU   A 1 46  ? -8.30800  20.83200 -15.32800 1.000 30.50461  ? 46  GLU   H N   1 
ATOM   327  C  CA  . GLU   A 1 46  ? -8.32400  21.73900 -16.47000 1.000 35.28240  ? 46  GLU   H CA  1 
ATOM   328  C  C   . GLU   A 1 46  ? -7.87300  20.96900 -17.70100 1.000 34.29390  ? 46  GLU   H C   1 
ATOM   329  O  O   . GLU   A 1 46  ? -6.73400  20.49600 -17.75200 1.000 33.81323  ? 46  GLU   H O   1 
ATOM   330  C  CB  . GLU   A 1 46  ? -7.41500  22.94700 -16.22200 1.000 33.38498  ? 46  GLU   H CB  1 
ATOM   331  C  CG  . GLU   A 1 46  ? -7.44600  24.00300 -17.31300 1.000 29.35531  ? 46  GLU   H CG  1 
ATOM   332  C  CD  . GLU   A 1 46  ? -6.22200  24.89900 -17.28300 1.000 36.12357  ? 46  GLU   H CD  1 
ATOM   333  O  OE1 . GLU   A 1 46  ? -6.21700  25.93000 -17.98800 1.000 38.77795  ? 46  GLU   H OE1 1 
ATOM   334  O  OE2 . GLU   A 1 46  ? -5.26100  24.57200 -16.55300 1.000 30.47412  ? 46  GLU   H OE2 1 
ATOM   335  N  N   . TRP   A 1 47  ? -8.76300  20.83900 -18.68300 1.000 33.02177  ? 47  TRP   H N   1 
ATOM   336  C  CA  . TRP   A 1 47  ? -8.43300  20.11200 -19.90200 1.000 23.92803  ? 47  TRP   H CA  1 
ATOM   337  C  C   . TRP   A 1 47  ? -7.40600  20.88900 -20.71500 1.000 33.56028  ? 47  TRP   H C   1 
ATOM   338  O  O   . TRP   A 1 47  ? -7.52700  22.10500 -20.89100 1.000 37.98747  ? 47  TRP   H O   1 
ATOM   339  C  CB  . TRP   A 1 47  ? -9.69400  19.86600 -20.72700 1.000 28.29021  ? 47  TRP   H CB  1 
ATOM   340  C  CG  . TRP   A 1 47  ? -9.42900  19.51000 -22.16200 1.000 38.09085  ? 47  TRP   H CG  1 
ATOM   341  C  CD1 . TRP   A 1 47  ? -9.15400  18.26900 -22.66600 1.000 33.57545  ? 47  TRP   H CD1 1 
ATOM   342  C  CD2 . TRP   A 1 47  ? -9.42500  20.40500 -23.28100 1.000 37.11182  ? 47  TRP   H CD2 1 
ATOM   343  N  NE1 . TRP   A 1 47  ? -8.97200  18.34000 -24.02600 1.000 33.56651  ? 47  TRP   H NE1 1 
ATOM   344  C  CE2 . TRP   A 1 47  ? -9.13400  19.64000 -24.42800 1.000 37.41886  ? 47  TRP   H CE2 1 
ATOM   345  C  CE3 . TRP   A 1 47  ? -9.63500  21.78000 -23.42300 1.000 36.32368  ? 47  TRP   H CE3 1 
ATOM   346  C  CZ2 . TRP   A 1 47  ? -9.04900  20.20500 -25.70000 1.000 37.07601  ? 47  TRP   H CZ2 1 
ATOM   347  C  CZ3 . TRP   A 1 47  ? -9.55000  22.33900 -24.68600 1.000 36.18060  ? 47  TRP   H CZ3 1 
ATOM   348  C  CH2 . TRP   A 1 47  ? -9.26000  21.55200 -25.80700 1.000 34.62115  ? 47  TRP   H CH2 1 
ATOM   349  N  N   . VAL   A 1 48  ? -6.39300  20.18400 -21.21400 1.000 30.78354  ? 48  VAL   H N   1 
ATOM   350  C  CA  . VAL   A 1 48  ? -5.26800  20.83100 -21.87900 1.000 35.40081  ? 48  VAL   H CA  1 
ATOM   351  C  C   . VAL   A 1 48  ? -5.37600  20.68100 -23.38900 1.000 30.10243  ? 48  VAL   H C   1 
ATOM   352  O  O   . VAL   A 1 48  ? -5.39100  21.67600 -24.12200 1.000 37.30592  ? 48  VAL   H O   1 
ATOM   353  C  CB  . VAL   A 1 48  ? -3.92900  20.26700 -21.37100 1.000 32.14025  ? 48  VAL   H CB  1 
ATOM   354  C  CG1 . VAL   A 1 48  ? -2.77000  20.99200 -22.03100 1.000 30.26482  ? 48  VAL   H CG1 1 
ATOM   355  C  CG2 . VAL   A 1 48  ? -3.84700  20.38300 -19.86000 1.000 29.13879  ? 48  VAL   H CG2 1 
ATOM   356  N  N   . SER   A 1 49  ? -5.43900  19.44200 -23.86800 1.000 33.11974  ? 49  SER   H N   1 
ATOM   357  C  CA  . SER   A 1 49  ? -5.40200  19.19900 -25.30200 1.000 33.49516  ? 49  SER   H CA  1 
ATOM   358  C  C   . SER   A 1 49  ? -5.96900  17.82400 -25.61300 1.000 34.20902  ? 49  SER   H C   1 
ATOM   359  O  O   . SER   A 1 49  ? -5.93000  16.91700 -24.77800 1.000 32.90090  ? 49  SER   H O   1 
ATOM   360  C  CB  . SER   A 1 49  ? -3.97600  19.31300 -25.85100 1.000 32.13432  ? 49  SER   H CB  1 
ATOM   361  O  OG  . SER   A 1 49  ? -3.99700  19.67200 -27.21800 1.000 43.07416  ? 49  SER   H OG  1 
ATOM   362  N  N   . SER   A 1 50  ? -6.48300  17.68500 -26.83500 1.000 29.31349  ? 50  SER   H N   1 
ATOM   363  C  CA  . SER   A 1 50  ? -7.02400  16.42800 -27.33000 1.000 33.15369  ? 50  SER   H CA  1 
ATOM   364  C  C   . SER   A 1 50  ? -6.62700  16.25400 -28.78900 1.000 33.71512  ? 50  SER   H C   1 
ATOM   365  O  O   . SER   A 1 50  ? -6.22500  17.20700 -29.46300 1.000 35.27329  ? 50  SER   H O   1 
ATOM   366  C  CB  . SER   A 1 50  ? -8.55000  16.37400 -27.19000 1.000 34.79983  ? 50  SER   H CB  1 
ATOM   367  O  OG  . SER   A 1 50  ? -8.93000  15.92100 -25.90400 1.000 37.10622  ? 50  SER   H OG  1 
ATOM   368  N  N   . ILE   A 1 51  ? -6.75500  15.02400 -29.27600 1.000 30.90468  ? 51  ILE   H N   1 
ATOM   369  C  CA  . ILE   A 1 51  ? -6.39100  14.69600 -30.65100 1.000 35.51105  ? 51  ILE   H CA  1 
ATOM   370  C  C   . ILE   A 1 51  ? -7.23500  13.51300 -31.10600 1.000 32.14188  ? 51  ILE   H C   1 
ATOM   371  O  O   . ILE   A 1 51  ? -7.43400  12.55100 -30.35900 1.000 27.70224  ? 51  ILE   H O   1 
ATOM   372  C  CB  . ILE   A 1 51  ? -4.87900  14.40500 -30.77300 1.000 27.45040  ? 51  ILE   H CB  1 
ATOM   373  C  CG1 . ILE   A 1 51  ? -4.49600  14.15500 -32.23100 1.000 27.77479  ? 51  ILE   H CG1 1 
ATOM   374  C  CG2 . ILE   A 1 51  ? -4.47700  13.23100 -29.89100 1.000 33.28467  ? 51  ILE   H CG2 1 
ATOM   375  C  CD1 . ILE   A 1 51  ? -3.00900  14.20000 -32.48000 1.000 28.68429  ? 51  ILE   H CD1 1 
ATOM   376  N  N   . SER   A 1 52  ? -7.74100  13.59300 -32.33400 1.000 35.67427  ? 52  SER   H N   1 
ATOM   377  C  CA  . SER   A 1 52  ? -8.59600  12.53800 -32.85300 1.000 35.57676  ? 52  SER   H CA  1 
ATOM   378  C  C   . SER   A 1 52  ? -7.77000  11.29800 -33.19400 1.000 38.12363  ? 52  SER   H C   1 
ATOM   379  O  O   . SER   A 1 52  ? -6.53700  11.29700 -33.13100 1.000 43.82236  ? 52  SER   H O   1 
ATOM   380  C  CB  . SER   A 1 52  ? -9.37000  13.02500 -34.07700 1.000 34.97424  ? 52  SER   H CB  1 
ATOM   381  O  OG  . SER   A 1 52  ? -8.51700  13.68500 -34.99300 1.000 38.98280  ? 52  SER   H OG  1 
ATOM   382  N  N   . ARG   A 1 53  ? -8.47700  10.22900 -33.57400 1.000 34.12574  ? 53  ARG   H N   1 
ATOM   383  C  CA  . ARG   A 1 53  ? -7.83300  8.92500  -33.71500 1.000 34.91137  ? 53  ARG   H CA  1 
ATOM   384  C  C   . ARG   A 1 53  ? -6.78500  8.91400  -34.82200 1.000 34.18351  ? 53  ARG   H C   1 
ATOM   385  O  O   . ARG   A 1 53  ? -5.84600  8.11200  -34.77300 1.000 39.21701  ? 53  ARG   H O   1 
ATOM   386  C  CB  . ARG   A 1 53  ? -8.88400  7.84100  -33.96600 1.000 32.82154  ? 53  ARG   H CB  1 
ATOM   387  C  CG  . ARG   A 1 53  ? -9.69400  8.01100  -35.24200 1.000 32.95491  ? 53  ARG   H CG  1 
ATOM   388  C  CD  . ARG   A 1 53  ? -10.82700 6.99500  -35.31100 1.000 34.13947  ? 53  ARG   H CD  1 
ATOM   389  N  NE  . ARG   A 1 53  ? -11.98000 7.39600  -34.50900 1.000 38.30580  ? 53  ARG   H NE  1 
ATOM   390  C  CZ  . ARG   A 1 53  ? -13.07900 6.66400  -34.35800 1.000 42.92650  ? 53  ARG   H CZ  1 
ATOM   391  N  NH1 . ARG   A 1 53  ? -13.18200 5.48400  -34.95500 1.000 45.21700  ? 53  ARG   H NH1 1 
ATOM   392  N  NH2 . ARG   A 1 53  ? -14.07800 7.11100  -33.60800 1.000 39.64627  ? 53  ARG   H NH2 1 
ATOM   393  N  N   . SER   A 1 54  ? -6.91500  9.78900  -35.82000 1.000 40.96377  ? 54  SER   H N   1 
ATOM   394  C  CA  . SER   A 1 54  ? -5.96600  9.84400  -36.92600 1.000 39.14980  ? 54  SER   H CA  1 
ATOM   395  C  C   . SER   A 1 54  ? -5.37200  11.23900 -37.09900 1.000 43.16807  ? 54  SER   H C   1 
ATOM   396  O  O   . SER   A 1 54  ? -5.01100  11.63300 -38.21000 1.000 43.57421  ? 54  SER   H O   1 
ATOM   397  C  CB  . SER   A 1 54  ? -6.62200  9.37600  -38.22500 1.000 34.74735  ? 54  SER   H CB  1 
ATOM   398  O  OG  . SER   A 1 54  ? -6.77100  7.96800  -38.24000 1.000 40.94984  ? 54  SER   H OG  1 
ATOM   399  N  N   . SER   A 1 55  ? -5.27500  11.99600 -36.00400 1.000 41.23647  ? 55  SER   H N   1 
ATOM   400  C  CA  . SER   A 1 55  ? -4.62100  13.30500 -35.96100 1.000 39.82209  ? 55  SER   H CA  1 
ATOM   401  C  C   . SER   A 1 55  ? -5.24100  14.31400 -36.92500 1.000 39.92240  ? 55  SER   H C   1 
ATOM   402  O  O   . SER   A 1 55  ? -4.62100  15.33500 -37.24000 1.000 40.89823  ? 55  SER   H O   1 
ATOM   403  C  CB  . SER   A 1 55  ? -3.11600  13.18200 -36.23300 1.000 42.00110  ? 55  SER   H CB  1 
ATOM   404  O  OG  . SER   A 1 55  ? -2.50300  12.28300 -35.32500 1.000 34.49834  ? 55  SER   H OG  1 
ATOM   405  N  N   . ASP   A 1 56  ? -6.46200  14.05700 -37.40000 1.000 41.77273  ? 56  ASP   H N   1 
ATOM   406  C  CA  . ASP   A 1 56  ? -7.09900  14.98600 -38.32800 1.000 37.72093  ? 56  ASP   H CA  1 
ATOM   407  C  C   . ASP   A 1 56  ? -7.59000  16.24000 -37.62200 1.000 41.21990  ? 56  ASP   H C   1 
ATOM   408  O  O   . ASP   A 1 56  ? -7.64900  17.31300 -38.23400 1.000 45.06865  ? 56  ASP   H O   1 
ATOM   409  C  CB  . ASP   A 1 56  ? -8.26300  14.30600 -39.04600 1.000 44.39143  ? 56  ASP   H CB  1 
ATOM   410  C  CG  . ASP   A 1 56  ? -7.84400  13.04900 -39.77200 1.000 47.87657  ? 56  ASP   H CG  1 
ATOM   411  O  OD1 . ASP   A 1 56  ? -7.28600  13.16300 -40.88300 1.000 50.34067  ? 56  ASP   H OD1 1 
ATOM   412  O  OD2 . ASP   A 1 56  ? -8.08000  11.94800 -39.23500 1.000 49.06488  ? 56  ASP   H OD2 1 
ATOM   413  N  N   . TYR   A 1 57  ? -7.95000  16.13000 -36.34600 1.000 39.40734  ? 57  TYR   H N   1 
ATOM   414  C  CA  . TYR   A 1 57  ? -8.50200  17.24500 -35.58800 1.000 34.12897  ? 57  TYR   H CA  1 
ATOM   415  C  C   . TYR   A 1 57  ? -7.72000  17.38500 -34.29300 1.000 34.35674  ? 57  TYR   H C   1 
ATOM   416  O  O   . TYR   A 1 57  ? -7.64500  16.43800 -33.50400 1.000 35.06503  ? 57  TYR   H O   1 
ATOM   417  C  CB  . TYR   A 1 57  ? -9.99200  17.03500 -35.31300 1.000 34.82328  ? 57  TYR   H CB  1 
ATOM   418  C  CG  . TYR   A 1 57  ? -10.76400 16.65400 -36.55300 1.000 41.57228  ? 57  TYR   H CG  1 
ATOM   419  C  CD1 . TYR   A 1 57  ? -11.13600 17.61500 -37.48400 1.000 44.03137  ? 57  TYR   H CD1 1 
ATOM   420  C  CD2 . TYR   A 1 57  ? -11.10200 15.33100 -36.80600 1.000 45.50129  ? 57  TYR   H CD2 1 
ATOM   421  C  CE1 . TYR   A 1 57  ? -11.83500 17.27200 -38.62500 1.000 39.97281  ? 57  TYR   H CE1 1 
ATOM   422  C  CE2 . TYR   A 1 57  ? -11.80000 14.97800 -37.94500 1.000 44.20118  ? 57  TYR   H CE2 1 
ATOM   423  C  CZ  . TYR   A 1 57  ? -12.16400 15.95200 -38.85000 1.000 49.37523  ? 57  TYR   H CZ  1 
ATOM   424  O  OH  . TYR   A 1 57  ? -12.85900 15.60500 -39.98500 1.000 60.52344  ? 57  TYR   H OH  1 
ATOM   425  N  N   . ILE   A 1 58  ? -7.14000  18.56200 -34.08200 1.000 32.47120  ? 58  ILE   H N   1 
ATOM   426  C  CA  . ILE   A 1 58  ? -6.28400  18.83700 -32.93600 1.000 31.94079  ? 58  ILE   H CA  1 
ATOM   427  C  C   . ILE   A 1 58  ? -6.86200  20.02600 -32.18300 1.000 30.52465  ? 58  ILE   H C   1 
ATOM   428  O  O   . ILE   A 1 58  ? -7.20100  21.04700 -32.79400 1.000 33.01356  ? 58  ILE   H O   1 
ATOM   429  C  CB  . ILE   A 1 58  ? -4.83400  19.10800 -33.37400 1.000 26.37618  ? 58  ILE   H CB  1 
ATOM   430  C  CG1 . ILE   A 1 58  ? -4.27000  17.89500 -34.11600 1.000 23.41162  ? 58  ILE   H CG1 1 
ATOM   431  C  CG2 . ILE   A 1 58  ? -3.97600  19.44300 -32.18100 1.000 27.18462  ? 58  ILE   H CG2 1 
ATOM   432  C  CD1 . ILE   A 1 58  ? -2.81500  18.03500 -34.49800 1.000 24.11326  ? 58  ILE   H CD1 1 
ATOM   433  N  N   . TYR   A 1 59  ? -6.97000  19.89600 -30.86300 1.000 28.10402  ? 59  TYR   H N   1 
ATOM   434  C  CA  . TYR   A 1 59  ? -7.63000  20.89300 -30.03300 1.000 32.08121  ? 59  TYR   H CA  1 
ATOM   435  C  C   . TYR   A 1 59  ? -6.74900  21.26500 -28.85100 1.000 32.95893  ? 59  TYR   H C   1 
ATOM   436  O  O   . TYR   A 1 59  ? -6.13500  20.39800 -28.22200 1.000 33.81197  ? 59  TYR   H O   1 
ATOM   437  C  CB  . TYR   A 1 59  ? -8.98300  20.37700 -29.53600 1.000 29.37690  ? 59  TYR   H CB  1 
ATOM   438  C  CG  . TYR   A 1 59  ? -9.96000  20.08100 -30.64900 1.000 35.67333  ? 59  TYR   H CG  1 
ATOM   439  C  CD1 . TYR   A 1 59  ? -10.77900 21.07800 -31.16200 1.000 28.75945  ? 59  TYR   H CD1 1 
ATOM   440  C  CD2 . TYR   A 1 59  ? -10.05600 18.80700 -31.19500 1.000 36.00433  ? 59  TYR   H CD2 1 
ATOM   441  C  CE1 . TYR   A 1 59  ? -11.67000 20.81500 -32.18100 1.000 37.93622  ? 59  TYR   H CE1 1 
ATOM   442  C  CE2 . TYR   A 1 59  ? -10.94600 18.53400 -32.21600 1.000 30.80497  ? 59  TYR   H CE2 1 
ATOM   443  C  CZ  . TYR   A 1 59  ? -11.75000 19.54300 -32.70500 1.000 39.06500  ? 59  TYR   H CZ  1 
ATOM   444  O  OH  . TYR   A 1 59  ? -12.63800 19.27900 -33.72100 1.000 45.92493  ? 59  TYR   H OH  1 
ATOM   445  N  N   . TYR   A 1 60  ? -6.69400  22.56200 -28.55300 1.000 31.73739  ? 60  TYR   H N   1 
ATOM   446  C  CA  . TYR   A 1 60  ? -5.95600  23.07600 -27.41100 1.000 37.30987  ? 60  TYR   H CA  1 
ATOM   447  C  C   . TYR   A 1 60  ? -6.83200  24.03500 -26.62000 1.000 38.69094  ? 60  TYR   H C   1 
ATOM   448  O  O   . TYR   A 1 60  ? -7.68400  24.73100 -27.18100 1.000 38.80065  ? 60  TYR   H O   1 
ATOM   449  C  CB  . TYR   A 1 60  ? -4.68100  23.81700 -27.83300 1.000 33.34306  ? 60  TYR   H CB  1 
ATOM   450  C  CG  . TYR   A 1 60  ? -3.74700  23.03800 -28.72200 1.000 36.81698  ? 60  TYR   H CG  1 
ATOM   451  C  CD1 . TYR   A 1 60  ? -2.77000  22.21500 -28.18000 1.000 35.29599  ? 60  TYR   H CD1 1 
ATOM   452  C  CD2 . TYR   A 1 60  ? -3.82200  23.14500 -30.10400 1.000 36.34528  ? 60  TYR   H CD2 1 
ATOM   453  C  CE1 . TYR   A 1 60  ? -1.90800  21.50200 -28.98700 1.000 30.55559  ? 60  TYR   H CE1 1 
ATOM   454  C  CE2 . TYR   A 1 60  ? -2.95800  22.44200 -30.92000 1.000 29.87191  ? 60  TYR   H CE2 1 
ATOM   455  C  CZ  . TYR   A 1 60  ? -2.00400  21.62000 -30.35500 1.000 32.83152  ? 60  TYR   H CZ  1 
ATOM   456  O  OH  . TYR   A 1 60  ? -1.14200  20.91300 -31.16100 1.000 33.80214  ? 60  TYR   H OH  1 
ATOM   457  N  N   . ALA   A 1 61  ? -6.61300  24.06700 -25.31000 1.000 38.72685  ? 61  ALA   H N   1 
ATOM   458  C  CA  . ALA   A 1 61  ? -7.18500  25.12500 -24.49400 1.000 37.03142  ? 61  ALA   H CA  1 
ATOM   459  C  C   . ALA   A 1 61  ? -6.44100  26.42900 -24.75400 1.000 40.64061  ? 61  ALA   H C   1 
ATOM   460  O  O   . ALA   A 1 61  ? -5.23800  26.43800 -25.03100 1.000 39.22887  ? 61  ALA   H O   1 
ATOM   461  C  CB  . ALA   A 1 61  ? -7.11900  24.76000 -23.01200 1.000 32.08374  ? 61  ALA   H CB  1 
ATOM   462  N  N   . ASP   A 1 62  ? -7.17400  27.54300 -24.67200 1.000 43.39595  ? 62  ASP   H N   1 
ATOM   463  C  CA  . ASP   A 1 62  ? -6.57300  28.84500 -24.95500 1.000 37.86319  ? 62  ASP   H CA  1 
ATOM   464  C  C   . ASP   A 1 62  ? -5.40500  29.14200 -24.02300 1.000 42.45957  ? 62  ASP   H C   1 
ATOM   465  O  O   . ASP   A 1 62  ? -4.51400  29.92600 -24.37300 1.000 41.48869  ? 62  ASP   H O   1 
ATOM   466  C  CB  . ASP   A 1 62  ? -7.62700  29.94700 -24.84800 1.000 42.04680  ? 62  ASP   H CB  1 
ATOM   467  C  CG  . ASP   A 1 62  ? -8.70100  29.83400 -25.91400 1.000 48.47347  ? 62  ASP   H CG  1 
ATOM   468  O  OD1 . ASP   A 1 62  ? -8.35900  29.55800 -27.08300 1.000 44.22249  ? 62  ASP   H OD1 1 
ATOM   469  O  OD2 . ASP   A 1 62  ? -9.89000  30.02000 -25.57900 1.000 54.63600  ? 62  ASP   H OD2 1 
ATOM   470  N  N   . SER   A 1 63  ? -5.38600  28.52400 -22.84000 1.000 35.44815  ? 63  SER   H N   1 
ATOM   471  C  CA  . SER   A 1 63  ? -4.29200  28.72900 -21.89800 1.000 32.72087  ? 63  SER   H CA  1 
ATOM   472  C  C   . SER   A 1 63  ? -2.96400  28.19500 -22.41600 1.000 34.72290  ? 63  SER   H C   1 
ATOM   473  O  O   . SER   A 1 63  ? -1.91000  28.64200 -21.95100 1.000 34.84041  ? 63  SER   H O   1 
ATOM   474  C  CB  . SER   A 1 63  ? -4.62400  28.06800 -20.56100 1.000 31.08890  ? 63  SER   H CB  1 
ATOM   475  O  OG  . SER   A 1 63  ? -5.34100  26.86100 -20.75300 1.000 45.33828  ? 63  SER   H OG  1 
ATOM   476  N  N   . VAL   A 1 64  ? -2.98500  27.25800 -23.36200 1.000 38.62512  ? 64  VAL   H N   1 
ATOM   477  C  CA  . VAL   A 1 64  ? -1.76300  26.64000 -23.86600 1.000 36.21372  ? 64  VAL   H CA  1 
ATOM   478  C  C   . VAL   A 1 64  ? -1.60400  26.76500 -25.37400 1.000 35.32814  ? 64  VAL   H C   1 
ATOM   479  O  O   . VAL   A 1 64  ? -0.57500  26.31700 -25.90400 1.000 34.18984  ? 64  VAL   H O   1 
ATOM   480  C  CB  . VAL   A 1 64  ? -1.66900  25.15400 -23.45600 1.000 40.12182  ? 64  VAL   H CB  1 
ATOM   481  C  CG1 . VAL   A 1 64  ? -1.95200  24.98300 -21.97100 1.000 32.16695  ? 64  VAL   H CG1 1 
ATOM   482  C  CG2 . VAL   A 1 64  ? -2.62000  24.30900 -24.29100 1.000 36.09101  ? 64  VAL   H CG2 1 
ATOM   483  N  N   . LYS   A 1 65  ? -2.57200  27.34300 -26.08700 1.000 34.02460  ? 65  LYS   H N   1 
ATOM   484  C  CA  . LYS   A 1 65  ? -2.46200  27.46400 -27.53600 1.000 36.83353  ? 65  LYS   H CA  1 
ATOM   485  C  C   . LYS   A 1 65  ? -1.21800  28.25400 -27.91600 1.000 33.80194  ? 65  LYS   H C   1 
ATOM   486  O  O   . LYS   A 1 65  ? -0.84900  29.22600 -27.25200 1.000 34.79988  ? 65  LYS   H O   1 
ATOM   487  C  CB  . LYS   A 1 65  ? -3.70600  28.13800 -28.12000 1.000 33.39696  ? 65  LYS   H CB  1 
ATOM   488  C  CG  . LYS   A 1 65  ? -4.70200  27.16700 -28.72900 1.000 40.75876  ? 65  LYS   H CG  1 
ATOM   489  C  CD  . LYS   A 1 65  ? -6.07600  27.79200 -28.90700 1.000 38.82064  ? 65  LYS   H CD  1 
ATOM   490  C  CE  . LYS   A 1 65  ? -6.74500  27.29400 -30.17900 1.000 55.50631  ? 65  LYS   H CE  1 
ATOM   491  N  NZ  . LYS   A 1 65  ? -7.40700  28.39100 -30.93700 1.000 67.32426  ? 65  LYS   H NZ  1 
ATOM   492  N  N   . GLY   A 1 66  ? -0.57200  27.82300 -28.99900 1.000 36.83651  ? 66  GLY   H N   1 
ATOM   493  C  CA  . GLY   A 1 66  ? 0.66800   28.41100 -29.44300 1.000 31.45444  ? 66  GLY   H CA  1 
ATOM   494  C  C   . GLY   A 1 66  ? 1.90000   27.95500 -28.69500 1.000 36.21475  ? 66  GLY   H C   1 
ATOM   495  O  O   . GLY   A 1 66  ? 3.01500   28.15900 -29.18800 1.000 43.64841  ? 66  GLY   H O   1 
ATOM   496  N  N   . ARG   A 1 67  ? 1.74300   27.34000 -27.52400 1.000 38.39721  ? 67  ARG   H N   1 
ATOM   497  C  CA  . ARG   A 1 67  ? 2.86800   26.89000 -26.71100 1.000 39.34594  ? 67  ARG   H CA  1 
ATOM   498  C  C   . ARG   A 1 67  ? 2.98400   25.37800 -26.61700 1.000 35.64567  ? 67  ARG   H C   1 
ATOM   499  O  O   . ARG   A 1 67  ? 4.09800   24.84900 -26.61600 1.000 35.24534  ? 67  ARG   H O   1 
ATOM   500  C  CB  . ARG   A 1 67  ? 2.76200   27.47000 -25.29700 1.000 36.88062  ? 67  ARG   H CB  1 
ATOM   501  C  CG  . ARG   A 1 67  ? 2.34400   28.92900 -25.24500 1.000 34.89190  ? 67  ARG   H CG  1 
ATOM   502  C  CD  . ARG   A 1 67  ? 1.76900   29.26000 -23.88400 1.000 31.33975  ? 67  ARG   H CD  1 
ATOM   503  N  NE  . ARG   A 1 67  ? 2.61000   28.72200 -22.82200 1.000 34.04861  ? 67  ARG   H NE  1 
ATOM   504  C  CZ  . ARG   A 1 67  ? 2.14700   28.23800 -21.67500 1.000 33.12572  ? 67  ARG   H CZ  1 
ATOM   505  N  NH1 . ARG   A 1 67  ? 0.84300   28.22500 -21.43500 1.000 30.00241  ? 67  ARG   H NH1 1 
ATOM   506  N  NH2 . ARG   A 1 67  ? 2.99000   27.76800 -20.76900 1.000 32.85816  ? 67  ARG   H NH2 1 
ATOM   507  N  N   . PHE   A 1 68  ? 1.86500   24.66600 -26.53200 1.000 32.95438  ? 68  PHE   H N   1 
ATOM   508  C  CA  . PHE   A 1 68  ? 1.86900   23.21400 -26.42500 1.000 33.26071  ? 68  PHE   H CA  1 
ATOM   509  C  C   . PHE   A 1 68  ? 1.49900   22.60000 -27.76800 1.000 37.12561  ? 68  PHE   H C   1 
ATOM   510  O  O   . PHE   A 1 68  ? 0.66100   23.13600 -28.49800 1.000 34.28718  ? 68  PHE   H O   1 
ATOM   511  C  CB  . PHE   A 1 68  ? 0.89100   22.72900 -25.35000 1.000 34.51846  ? 68  PHE   H CB  1 
ATOM   512  C  CG  . PHE   A 1 68  ? 1.31200   23.05100 -23.93900 1.000 40.01976  ? 68  PHE   H CG  1 
ATOM   513  C  CD1 . PHE   A 1 68  ? 2.43100   23.82700 -23.68300 1.000 42.25305  ? 68  PHE   H CD1 1 
ATOM   514  C  CD2 . PHE   A 1 68  ? 0.58400   22.56600 -22.86500 1.000 38.79694  ? 68  PHE   H CD2 1 
ATOM   515  C  CE1 . PHE   A 1 68  ? 2.80900   24.12100 -22.38800 1.000 33.95394  ? 68  PHE   H CE1 1 
ATOM   516  C  CE2 . PHE   A 1 68  ? 0.95900   22.85500 -21.56800 1.000 41.91411  ? 68  PHE   H CE2 1 
ATOM   517  C  CZ  . PHE   A 1 68  ? 2.07300   23.63200 -21.32900 1.000 37.78805  ? 68  PHE   H CZ  1 
ATOM   518  N  N   . THR   A 1 69  ? 2.13300   21.47400 -28.08900 1.000 36.36405  ? 69  THR   H N   1 
ATOM   519  C  CA  . THR   A 1 69  ? 1.83200   20.71700 -29.29700 1.000 35.39704  ? 69  THR   H CA  1 
ATOM   520  C  C   . THR   A 1 69  ? 1.55100   19.27200 -28.91600 1.000 36.96067  ? 69  THR   H C   1 
ATOM   521  O  O   . THR   A 1 69  ? 2.33000   18.65900 -28.17900 1.000 32.82780  ? 69  THR   H O   1 
ATOM   522  C  CB  . THR   A 1 69  ? 2.98400   20.77800 -30.30500 1.000 33.83484  ? 69  THR   H CB  1 
ATOM   523  O  OG1 . THR   A 1 69  ? 3.40000   22.13800 -30.47700 1.000 34.61599  ? 69  THR   H OG1 1 
ATOM   524  C  CG2 . THR   A 1 69  ? 2.54200   20.21300 -31.64800 1.000 34.94375  ? 69  THR   H CG2 1 
ATOM   525  N  N   . ILE   A 1 70  ? 0.44200   18.73400 -29.41500 1.000 36.94995  ? 70  ILE   H N   1 
ATOM   526  C  CA  . ILE   A 1 70  ? 0.06300   17.35100 -29.16600 1.000 27.22230  ? 70  ILE   H CA  1 
ATOM   527  C  C   . ILE   A 1 70  ? 0.28100   16.55500 -30.44400 1.000 26.58525  ? 70  ILE   H C   1 
ATOM   528  O  O   . ILE   A 1 70  ? 0.26000   17.09900 -31.55600 1.000 29.72904  ? 70  ILE   H O   1 
ATOM   529  C  CB  . ILE   A 1 70  ? -1.39800  17.23000 -28.67500 1.000 30.94386  ? 70  ILE   H CB  1 
ATOM   530  C  CG1 . ILE   A 1 70  ? -1.62500  15.89100 -27.97000 1.000 29.65686  ? 70  ILE   H CG1 1 
ATOM   531  C  CG2 . ILE   A 1 70  ? -2.36800  17.38000 -29.82600 1.000 32.72853  ? 70  ILE   H CG2 1 
ATOM   532  C  CD1 . ILE   A 1 70  ? -3.06000  15.66000 -27.54400 1.000 24.58405  ? 70  ILE   H CD1 1 
ATOM   533  N  N   . SER   A 1 71  ? 0.50500   15.25500 -30.27600 1.000 31.88625  ? 71  SER   H N   1 
ATOM   534  C  CA  . SER   A 1 71  ? 0.73000   14.33800 -31.38400 1.000 27.52051  ? 71  SER   H CA  1 
ATOM   535  C  C   . SER   A 1 71  ? 0.63000   12.92000 -30.84700 1.000 33.16361  ? 71  SER   H C   1 
ATOM   536  O  O   . SER   A 1 71  ? 0.77500   12.68500 -29.64300 1.000 29.45113  ? 71  SER   H O   1 
ATOM   537  C  CB  . SER   A 1 71  ? 2.09400   14.57000 -32.04500 1.000 29.84315  ? 71  SER   H CB  1 
ATOM   538  O  OG  . SER   A 1 71  ? 3.15200   14.30400 -31.14000 1.000 32.11050  ? 71  SER   H OG  1 
ATOM   539  N  N   . ARG   A 1 72  ? 0.38200   11.97800 -31.75100 1.000 36.36025  ? 72  ARG   H N   1 
ATOM   540  C  CA  . ARG   A 1 72  ? 0.31900   10.57100 -31.39100 1.000 31.57411  ? 72  ARG   H CA  1 
ATOM   541  C  C   . ARG   A 1 72  ? 1.07800   9.74500  -32.42300 1.000 31.10347  ? 72  ARG   H C   1 
ATOM   542  O  O   . ARG   A 1 72  ? 1.54800   10.25400 -33.44500 1.000 32.82313  ? 72  ARG   H O   1 
ATOM   543  C  CB  . ARG   A 1 72  ? -1.13200  10.08700 -31.26300 1.000 27.81791  ? 72  ARG   H CB  1 
ATOM   544  C  CG  . ARG   A 1 72  ? -1.96400  10.22200 -32.52400 1.000 27.23916  ? 72  ARG   H CG  1 
ATOM   545  C  CD  . ARG   A 1 72  ? -3.45200  10.12300 -32.20800 1.000 31.46793  ? 72  ARG   H CD  1 
ATOM   546  N  NE  . ARG   A 1 72  ? -3.85500  8.76200  -31.86000 1.000 33.27508  ? 72  ARG   H NE  1 
ATOM   547  C  CZ  . ARG   A 1 72  ? -5.00300  8.45100  -31.26500 1.000 31.60272  ? 72  ARG   H CZ  1 
ATOM   548  N  NH1 . ARG   A 1 72  ? -5.28700  7.18500  -30.98600 1.000 34.33124  ? 72  ARG   H NH1 1 
ATOM   549  N  NH2 . ARG   A 1 72  ? -5.86800  9.40400  -30.94700 1.000 30.41331  ? 72  ARG   H NH2 1 
ATOM   550  N  N   . ASP   A 1 73  ? 1.20700   8.45200  -32.12900 1.000 34.53068  ? 73  ASP   H N   1 
ATOM   551  C  CA  . ASP   A 1 73  ? 1.80000   7.49000  -33.05500 1.000 36.33458  ? 73  ASP   H CA  1 
ATOM   552  C  C   . ASP   A 1 73  ? 1.03100   6.18800  -32.85600 1.000 34.93759  ? 73  ASP   H C   1 
ATOM   553  O  O   . ASP   A 1 73  ? 1.27100   5.46600  -31.88400 1.000 37.17609  ? 73  ASP   H O   1 
ATOM   554  C  CB  . ASP   A 1 73  ? 3.29200   7.31500  -32.80100 1.000 40.28374  ? 73  ASP   H CB  1 
ATOM   555  C  CG  . ASP   A 1 73  ? 3.96200   6.40700  -33.82200 1.000 40.31179  ? 73  ASP   H CG  1 
ATOM   556  O  OD1 . ASP   A 1 73  ? 3.25800   5.82300  -34.67400 1.000 36.40092  ? 73  ASP   H OD1 1 
ATOM   557  O  OD2 . ASP   A 1 73  ? 5.20400   6.27600  -33.77200 1.000 37.55068  ? 73  ASP   H OD2 1 
ATOM   558  N  N   . ASN   A 1 74  ? 0.10400   5.90300  -33.77100 1.000 32.66751  ? 74  ASN   H N   1 
ATOM   559  C  CA  . ASN   A 1 74  ? -0.74900  4.72900  -33.63500 1.000 29.75575  ? 74  ASN   H CA  1 
ATOM   560  C  C   . ASN   A 1 74  ? 0.01200   3.42000  -33.80200 1.000 34.21131  ? 74  ASN   H C   1 
ATOM   561  O  O   . ASN   A 1 74  ? -0.57100  2.35400  -33.57300 1.000 36.90136  ? 74  ASN   H O   1 
ATOM   562  C  CB  . ASN   A 1 74  ? -1.89600  4.80200  -34.64300 1.000 31.65193  ? 74  ASN   H CB  1 
ATOM   563  C  CG  . ASN   A 1 74  ? -2.96000  5.80400  -34.24100 1.000 31.80509  ? 74  ASN   H CG  1 
ATOM   564  O  OD1 . ASN   A 1 74  ? -2.95600  6.31600  -33.12100 1.000 33.35682  ? 74  ASN   H OD1 1 
ATOM   565  N  ND2 . ASN   A 1 74  ? -3.88000  6.09000  -35.15400 1.000 31.92675  ? 74  ASN   H ND2 1 
ATOM   566  N  N   . ALA   A 1 75  ? 1.28300   3.46900  -34.19400 1.000 31.18121  ? 75  ALA   H N   1 
ATOM   567  C  CA  . ALA   A 1 75  ? 2.11800   2.27800  -34.25900 1.000 26.38307  ? 75  ALA   H CA  1 
ATOM   568  C  C   . ALA   A 1 75  ? 2.84500   1.99600  -32.95200 1.000 33.65917  ? 75  ALA   H C   1 
ATOM   569  O  O   . ALA   A 1 75  ? 3.45800   0.93100  -32.81900 1.000 39.85210  ? 75  ALA   H O   1 
ATOM   570  C  CB  . ALA   A 1 75  ? 3.13900   2.40500  -35.39300 1.000 27.55957  ? 75  ALA   H CB  1 
ATOM   571  N  N   . LYS   A 1 76  ? 2.79600   2.92000  -31.99200 1.000 34.67824  ? 76  LYS   H N   1 
ATOM   572  C  CA  . LYS   A 1 76  ? 3.40600   2.72500  -30.68300 1.000 34.38165  ? 76  LYS   H CA  1 
ATOM   573  C  C   . LYS   A 1 76  ? 2.40900   2.91000  -29.54600 1.000 33.81919  ? 76  LYS   H C   1 
ATOM   574  O  O   . LYS   A 1 76  ? 2.80600   2.85500  -28.37700 1.000 37.73401  ? 76  LYS   H O   1 
ATOM   575  C  CB  . LYS   A 1 76  ? 4.59300   3.67600  -30.49900 1.000 34.93561  ? 76  LYS   H CB  1 
ATOM   576  C  CG  . LYS   A 1 76  ? 5.84000   3.27000  -31.27300 1.000 41.44875  ? 76  LYS   H CG  1 
ATOM   577  C  CD  . LYS   A 1 76  ? 6.73600   4.46400  -31.56700 1.000 41.80071  ? 76  LYS   H CD  1 
ATOM   578  C  CE  . LYS   A 1 76  ? 7.17900   5.15600  -30.28700 1.000 49.81807  ? 76  LYS   H CE  1 
ATOM   579  N  NZ  . LYS   A 1 76  ? 7.32000   6.62900  -30.47000 1.000 44.54197  ? 76  LYS   H NZ  1 
ATOM   580  N  N   . ASN   A 1 77  ? 1.13000   3.12500  -29.85900 1.000 31.98072  ? 77  ASN   H N   1 
ATOM   581  C  CA  . ASN   A 1 77  ? 0.08200   3.31900  -28.85500 1.000 33.23963  ? 77  ASN   H CA  1 
ATOM   582  C  C   . ASN   A 1 77  ? 0.46900   4.41500  -27.86400 1.000 35.94033  ? 77  ASN   H C   1 
ATOM   583  O  O   . ASN   A 1 77  ? 0.38600   4.24700  -26.64500 1.000 38.39469  ? 77  ASN   H O   1 
ATOM   584  C  CB  . ASN   A 1 77  ? -0.22800  2.00900  -28.12800 1.000 33.15449  ? 77  ASN   H CB  1 
ATOM   585  C  CG  . ASN   A 1 77  ? -1.15400  1.10700  -28.91900 1.000 32.57660  ? 77  ASN   H CG  1 
ATOM   586  O  OD1 . ASN   A 1 77  ? -1.44400  1.36500  -30.08700 1.000 34.30106  ? 77  ASN   H OD1 1 
ATOM   587  N  ND2 . ASN   A 1 77  ? -1.62500  0.04000  -28.28300 1.000 34.46651  ? 77  ASN   H ND2 1 
ATOM   588  N  N   . SER   A 1 78  ? 0.89800   5.55500  -28.40000 1.000 37.41337  ? 78  SER   H N   1 
ATOM   589  C  CA  . SER   A 1 78  ? 1.46700   6.60800  -27.57400 1.000 34.99302  ? 78  SER   H CA  1 
ATOM   590  C  C   . SER   A 1 78  ? 1.00100   7.97300  -28.05300 1.000 36.55450  ? 78  SER   H C   1 
ATOM   591  O  O   . SER   A 1 78  ? 0.90600   8.22200  -29.25700 1.000 33.94206  ? 78  SER   H O   1 
ATOM   592  C  CB  . SER   A 1 78  ? 2.99900   6.55000  -27.58800 1.000 40.95405  ? 78  SER   H CB  1 
ATOM   593  O  OG  . SER   A 1 78  ? 3.48400   5.68000  -26.58100 1.000 40.29089  ? 78  SER   H OG  1 
ATOM   594  N  N   . VAL   A 1 79  ? 0.71600   8.85000  -27.09400 1.000 39.42808  ? 79  VAL   H N   1 
ATOM   595  C  CA  . VAL   A 1 79  ? 0.38700   10.24500 -27.34700 1.000 36.73111  ? 79  VAL   H CA  1 
ATOM   596  C  C   . VAL   A 1 79  ? 1.43100   11.10300 -26.64600 1.000 33.60334  ? 79  VAL   H C   1 
ATOM   597  O  O   . VAL   A 1 79  ? 1.98600   10.71500 -25.61200 1.000 33.06552  ? 79  VAL   H O   1 
ATOM   598  C  CB  . VAL   A 1 79  ? -1.04500  10.59200 -26.87300 1.000 34.09225  ? 79  VAL   H CB  1 
ATOM   599  C  CG1 . VAL   A 1 79  ? -1.14000  10.54200 -25.35500 1.000 32.09107  ? 79  VAL   H CG1 1 
ATOM   600  C  CG2 . VAL   A 1 79  ? -1.48300  11.95100 -27.40500 1.000 30.42872  ? 79  VAL   H CG2 1 
ATOM   601  N  N   . TYR   A 1 80  ? 1.71500   12.26700 -27.22400 1.000 34.05321  ? 80  TYR   H N   1 
ATOM   602  C  CA  . TYR   A 1 80  ? 2.79900   13.11400 -26.75600 1.000 36.29194  ? 80  TYR   H CA  1 
ATOM   603  C  C   . TYR   A 1 80  ? 2.31400   14.54700 -26.58300 1.000 34.84806  ? 80  TYR   H C   1 
ATOM   604  O  O   . TYR   A 1 80  ? 1.29600   14.95500 -27.14700 1.000 33.40407  ? 80  TYR   H O   1 
ATOM   605  C  CB  . TYR   A 1 80  ? 3.99000   13.06900 -27.72200 1.000 33.85844  ? 80  TYR   H CB  1 
ATOM   606  C  CG  . TYR   A 1 80  ? 4.44700   11.66500 -28.04200 1.000 35.68385  ? 80  TYR   H CG  1 
ATOM   607  C  CD1 . TYR   A 1 80  ? 5.39100   11.02800 -27.25200 1.000 40.47830  ? 80  TYR   H CD1 1 
ATOM   608  C  CD2 . TYR   A 1 80  ? 3.93000   10.97300 -29.13000 1.000 41.33371  ? 80  TYR   H CD2 1 
ATOM   609  C  CE1 . TYR   A 1 80  ? 5.81400   9.74400  -27.53600 1.000 36.67949  ? 80  TYR   H CE1 1 
ATOM   610  C  CE2 . TYR   A 1 80  ? 4.34600   9.68500  -29.42100 1.000 45.65053  ? 80  TYR   H CE2 1 
ATOM   611  C  CZ  . TYR   A 1 80  ? 5.28900   9.07700  -28.62000 1.000 40.95833  ? 80  TYR   H CZ  1 
ATOM   612  O  OH  . TYR   A 1 80  ? 5.70900   7.79800  -28.90300 1.000 42.62871  ? 80  TYR   H OH  1 
ATOM   613  N  N   . LEU   A 1 81  ? 3.06400   15.30800 -25.78700 1.000 30.73138  ? 81  LEU   H N   1 
ATOM   614  C  CA  . LEU   A 1 81  ? 2.75000   16.71100 -25.51800 1.000 31.12753  ? 81  LEU   H CA  1 
ATOM   615  C  C   . LEU   A 1 81  ? 4.06500   17.47800 -25.42700 1.000 34.14175  ? 81  LEU   H C   1 
ATOM   616  O  O   . LEU   A 1 81  ? 4.76200   17.40700 -24.41100 1.000 36.76059  ? 81  LEU   H O   1 
ATOM   617  C  CB  . LEU   A 1 81  ? 1.93500   16.86200 -24.23900 1.000 32.97214  ? 81  LEU   H CB  1 
ATOM   618  C  CG  . LEU   A 1 81  ? 1.29400   18.23400 -24.01900 1.000 36.06671  ? 81  LEU   H CG  1 
ATOM   619  C  CD1 . LEU   A 1 81  ? 0.27900   18.53200 -25.11100 1.000 38.38227  ? 81  LEU   H CD1 1 
ATOM   620  C  CD2 . LEU   A 1 81  ? 0.65000   18.30700 -22.64500 1.000 31.57608  ? 81  LEU   H CD2 1 
ATOM   621  N  N   . GLN   A 1 82  ? 4.40100   18.20700 -26.48900 1.000 32.62455  ? 82  GLN   H N   1 
ATOM   622  C  CA  . GLN   A 1 82  ? 5.57300   19.07500 -26.47600 1.000 33.70555  ? 82  GLN   H CA  1 
ATOM   623  C  C   . GLN   A 1 82  ? 5.18900   20.39900 -25.82800 1.000 37.04052  ? 82  GLN   H C   1 
ATOM   624  O  O   . GLN   A 1 82  ? 4.45500   21.19900 -26.41800 1.000 36.79341  ? 82  GLN   H O   1 
ATOM   625  C  CB  . GLN   A 1 82  ? 6.10800   19.28800 -27.88800 1.000 24.69995  ? 82  GLN   H CB  1 
ATOM   626  C  CG  . GLN   A 1 82  ? 7.43100   20.03300 -27.92900 1.000 26.74677  ? 82  GLN   H CG  1 
ATOM   627  C  CD  . GLN   A 1 82  ? 8.45700   19.44500 -26.98000 1.000 36.61428  ? 82  GLN   H CD  1 
ATOM   628  O  OE1 . GLN   A 1 82  ? 8.94500   18.33500 -27.18800 1.000 39.21829  ? 82  GLN   H OE1 1 
ATOM   629  N  NE2 . GLN   A 1 82  ? 8.78500   20.18700 -25.92700 1.000 37.03390  ? 82  GLN   H NE2 1 
ATOM   630  N  N   . MET   A 1 83  ? 5.67500   20.62900 -24.61400 1.000 33.63019  ? 83  MET   H N   1 
ATOM   631  C  CA  . MET   A 1 83  ? 5.42300   21.86600 -23.89100 1.000 34.54025  ? 83  MET   H CA  1 
ATOM   632  C  C   . MET   A 1 83  ? 6.59800   22.81200 -24.09500 1.000 40.20771  ? 83  MET   H C   1 
ATOM   633  O  O   . MET   A 1 83  ? 7.75500   22.40900 -23.95000 1.000 43.12662  ? 83  MET   H O   1 
ATOM   634  C  CB  . MET   A 1 83  ? 5.20900   21.59100 -22.40100 1.000 36.52985  ? 83  MET   H CB  1 
ATOM   635  C  CG  . MET   A 1 83  ? 4.15700   20.52700 -22.11500 1.000 37.98782  ? 83  MET   H CG  1 
ATOM   636  S  SD  . MET   A 1 83  ? 3.78100   20.35600 -20.35900 1.000 45.87144  ? 83  MET   H SD  1 
ATOM   637  C  CE  . MET   A 1 83  ? 5.42900   20.23500 -19.67000 1.000 35.92791  ? 83  MET   H CE  1 
ATOM   638  N  N   . THR   A 1 84  ? 6.29900   24.05900 -24.45600 1.000 41.48076  ? 84  THR   H N   1 
ATOM   639  C  CA  . THR   A 1 84  ? 7.30200   25.10200 -24.61400 1.000 39.35435  ? 84  THR   H CA  1 
ATOM   640  C  C   . THR   A 1 84  ? 6.82300   26.36600 -23.91400 1.000 38.04371  ? 84  THR   H C   1 
ATOM   641  O  O   . THR   A 1 84  ? 5.62800   26.53900 -23.65700 1.000 38.76276  ? 84  THR   H O   1 
ATOM   642  C  CB  . THR   A 1 84  ? 7.59100   25.41800 -26.09100 1.000 39.60025  ? 84  THR   H CB  1 
ATOM   643  O  OG1 . THR   A 1 84  ? 6.44900   26.05500 -26.67600 1.000 37.50222  ? 84  THR   H OG1 1 
ATOM   644  C  CG2 . THR   A 1 84  ? 7.91800   24.15000 -26.87100 1.000 37.25801  ? 84  THR   H CG2 1 
ATOM   645  N  N   . SER   A 1 85  ? 7.77200   27.25300 -23.62000 1.000 35.77221  ? 85  SER   H N   1 
ATOM   646  C  CA  . SER   A 1 85  ? 7.49600   28.52800 -22.95600 1.000 36.38756  ? 85  SER   H CA  1 
ATOM   647  C  C   . SER   A 1 85  ? 6.66700   28.30700 -21.69000 1.000 36.36167  ? 85  SER   H C   1 
ATOM   648  O  O   . SER   A 1 85  ? 5.53100   28.76400 -21.56200 1.000 35.05168  ? 85  SER   H O   1 
ATOM   649  C  CB  . SER   A 1 85  ? 6.79500   29.49900 -23.91100 1.000 38.41645  ? 85  SER   H CB  1 
ATOM   650  O  OG  . SER   A 1 85  ? 7.70900   30.07300 -24.82900 1.000 43.13115  ? 85  SER   H OG  1 
ATOM   651  N  N   . LEU   A 1 86  ? 7.26300   27.58400 -20.74700 1.000 40.20900  ? 86  LEU   H N   1 
ATOM   652  C  CA  . LEU   A 1 86  ? 6.52300   27.10100 -19.59100 1.000 38.75498  ? 86  LEU   H CA  1 
ATOM   653  C  C   . LEU   A 1 86  ? 6.42000   28.17000 -18.51000 1.000 46.64361  ? 86  LEU   H C   1 
ATOM   654  O  O   . LEU   A 1 86  ? 7.39900   28.84600 -18.18300 1.000 44.36601  ? 86  LEU   H O   1 
ATOM   655  C  CB  . LEU   A 1 86  ? 7.18400   25.84100 -19.03700 1.000 34.73445  ? 86  LEU   H CB  1 
ATOM   656  C  CG  . LEU   A 1 86  ? 6.75500   24.59700 -19.81700 1.000 35.95734  ? 86  LEU   H CG  1 
ATOM   657  C  CD1 . LEU   A 1 86  ? 7.68100   23.42400 -19.55700 1.000 40.01869  ? 86  LEU   H CD1 1 
ATOM   658  C  CD2 . LEU   A 1 86  ? 5.31800   24.23800 -19.47800 1.000 34.92088  ? 86  LEU   H CD2 1 
ATOM   659  N  N   . ARG   A 1 87  ? 5.21800   28.31400 -17.95600 1.000 46.76693  ? 87  ARG   H N   1 
ATOM   660  C  CA  . ARG   A 1 87  ? 4.91700   29.30300 -16.93300 1.000 37.48164  ? 87  ARG   H CA  1 
ATOM   661  C  C   . ARG   A 1 87  ? 4.63800   28.62100 -15.59900 1.000 43.91671  ? 87  ARG   H C   1 
ATOM   662  O  O   . ARG   A 1 87  ? 4.45400   27.40300 -15.52200 1.000 41.69234  ? 87  ARG   H O   1 
ATOM   663  C  CB  . ARG   A 1 87  ? 3.70600   30.15300 -17.33100 1.000 36.76654  ? 87  ARG   H CB  1 
ATOM   664  C  CG  . ARG   A 1 87  ? 3.85800   30.91300 -18.63400 1.000 42.88618  ? 87  ARG   H CG  1 
ATOM   665  C  CD  . ARG   A 1 87  ? 2.48900   31.23700 -19.21000 1.000 42.31438  ? 87  ARG   H CD  1 
ATOM   666  N  NE  . ARG   A 1 87  ? 2.56800   31.82700 -20.54200 1.000 39.25355  ? 87  ARG   H NE  1 
ATOM   667  C  CZ  . ARG   A 1 87  ? 1.54100   31.91200 -21.38100 1.000 41.09545  ? 87  ARG   H CZ  1 
ATOM   668  N  NH1 . ARG   A 1 87  ? 0.35300   31.43700 -21.03000 1.000 37.27191  ? 87  ARG   H NH1 1 
ATOM   669  N  NH2 . ARG   A 1 87  ? 1.70200   32.46800 -22.57300 1.000 38.52744  ? 87  ARG   H NH2 1 
ATOM   670  N  N   . ASP   A 1 88  ? 4.60400   29.43600 -14.54000 1.000 48.37690  ? 88  ASP   H N   1 
ATOM   671  C  CA  . ASP   A 1 88  ? 4.27100   28.92100 -13.21500 1.000 47.61834  ? 88  ASP   H CA  1 
ATOM   672  C  C   . ASP   A 1 88  ? 2.87600   28.30800 -13.19600 1.000 47.46725  ? 88  ASP   H C   1 
ATOM   673  O  O   . ASP   A 1 88  ? 2.64400   27.29400 -12.52700 1.000 44.87091  ? 88  ASP   H O   1 
ATOM   674  C  CB  . ASP   A 1 88  ? 4.37900   30.03800 -12.17600 1.000 50.85019  ? 88  ASP   H CB  1 
ATOM   675  C  CG  . ASP   A 1 88  ? 4.54300   29.50800 -10.76400 1.000 57.08305  ? 88  ASP   H CG  1 
ATOM   676  O  OD1 . ASP   A 1 88  ? 5.69500   29.26300 -10.34700 1.000 54.24203  ? 88  ASP   H OD1 1 
ATOM   677  O  OD2 . ASP   A 1 88  ? 3.51800   29.33700 -10.07000 1.000 58.84417  ? 88  ASP   H OD2 1 
ATOM   678  N  N   . GLU   A 1 89  ? 1.97100   28.81700 -14.00600 1.000 46.83010  ? 89  GLU   H N   1 
ATOM   679  C  CA  . GLU   A 1 89  ? 0.57600   28.33100 -14.02000 1.000 43.12567  ? 89  GLU   H CA  1 
ATOM   680  C  C   . GLU   A 1 89  ? 0.53200   26.93000 -14.58900 1.000 42.14490  ? 89  GLU   H C   1 
ATOM   681  O  O   . GLU   A 1 89  ? -0.48600  26.26300 -14.42500 1.000 45.07308  ? 89  GLU   H O   1 
ATOM   682  C  CB  . GLU   A 1 89  ? -0.24800  29.24200 -14.92000 1.000 41.45212  ? 89  GLU   H CB  1 
ATOM   683  C  CG  . GLU   A 1 89  ? 0.58200   30.03000 -15.90800 1.000 50.43343  ? 89  GLU   H CG  1 
ATOM   684  C  CD  . GLU   A 1 89  ? 0.90800   31.44700 -15.47400 1.000 60.52093  ? 89  GLU   H CD  1 
ATOM   685  O  OE1 . GLU   A 1 89  ? 1.89200   31.62600 -14.73600 1.000 53.81126  ? 89  GLU   H OE1 1 
ATOM   686  O  OE2 . GLU   A 1 89  ? 0.17800   32.36500 -15.88100 1.000 65.62228  ? 89  GLU   H OE2 1 
ATOM   687  N  N   . ASP   A 1 90  ? 1.60700   26.52100 -15.23500 1.000 42.55877  ? 90  ASP   H N   1 
ATOM   688  C  CA  . ASP   A 1 90  ? 1.62300   25.21400 -15.92500 1.000 37.44629  ? 90  ASP   H CA  1 
ATOM   689  C  C   . ASP   A 1 90  ? 2.11800   24.16900 -14.94200 1.000 39.08999  ? 90  ASP   H C   1 
ATOM   690  O  O   . ASP   A 1 90  ? 2.13900   23.00900 -15.29100 1.000 35.86483  ? 90  ASP   H O   1 
ATOM   691  C  CB  . ASP   A 1 90  ? 2.42100   25.33100 -17.21500 1.000 31.25998  ? 90  ASP   H CB  1 
ATOM   692  C  CG  . ASP   A 1 90  ? 1.95900   26.45700 -18.09800 1.000 37.75952  ? 90  ASP   H CG  1 
ATOM   693  O  OD1 . ASP   A 1 90  ? 0.77700   26.48900 -18.44400 1.000 39.54512  ? 90  ASP   H OD1 1 
ATOM   694  O  OD2 . ASP   A 1 90  ? 2.79200   27.27800 -18.40800 1.000 39.06743  ? 90  ASP   H OD2 1 
ATOM   695  N  N   . THR   A 1 91  ? 2.49000   24.60200 -13.74900 1.000 39.97283  ? 91  THR   H N   1 
ATOM   696  C  CA  . THR   A 1 91  ? 2.84200   23.63100 -12.71800 1.000 40.31252  ? 91  THR   H CA  1 
ATOM   697  C  C   . THR   A 1 91  ? 1.59800   22.83800 -12.34500 1.000 43.30314  ? 91  THR   H C   1 
ATOM   698  O  O   . THR   A 1 91  ? 0.67500   23.37100 -11.71900 1.000 44.42269  ? 91  THR   H O   1 
ATOM   699  C  CB  . THR   A 1 91  ? 3.42900   24.32700 -11.49500 1.000 43.44816  ? 91  THR   H CB  1 
ATOM   700  O  OG1 . THR   A 1 91  ? 4.65800   24.97300 -11.85100 1.000 46.58533  ? 91  THR   H OG1 1 
ATOM   701  C  CG2 . THR   A 1 91  ? 3.69600   23.31600 -10.38800 1.000 36.65829  ? 91  THR   H CG2 1 
ATOM   702  N  N   . ALA   A 1 92  ? 1.56600   21.56600 -12.73100 1.000 35.81327  ? 92  ALA   H N   1 
ATOM   703  C  CA  . ALA   A 1 92  ? 0.39500   20.73200 -12.50800 1.000 33.56935  ? 92  ALA   H CA  1 
ATOM   704  C  C   . ALA   A 1 92  ? 0.79500   19.27300 -12.66300 1.000 36.35268  ? 92  ALA   H C   1 
ATOM   705  O  O   . ALA   A 1 92  ? 1.88900   18.95200 -13.13500 1.000 38.32764  ? 92  ALA   H O   1 
ATOM   706  C  CB  . ALA   A 1 92  ? -0.73600  21.09200 -13.47700 1.000 32.50843  ? 92  ALA   H CB  1 
ATOM   707  N  N   . VAL   A 1 93  ? -0.10700  18.39100 -12.24700 1.000 33.83052  ? 93  VAL   H N   1 
ATOM   708  C  CA  . VAL   A 1 93  ? -0.00400  16.96900 -12.55000 1.000 35.35611  ? 93  VAL   H CA  1 
ATOM   709  C  C   . VAL   A 1 93  ? -0.74800  16.72600 -13.85600 1.000 35.55884  ? 93  VAL   H C   1 
ATOM   710  O  O   . VAL   A 1 93  ? -1.94000  17.03100 -13.96600 1.000 36.52364  ? 93  VAL   H O   1 
ATOM   711  C  CB  . VAL   A 1 93  ? -0.58000  16.11000 -11.41500 1.000 27.31342  ? 93  VAL   H CB  1 
ATOM   712  C  CG1 . VAL   A 1 93  ? -0.83800  14.69400 -11.90500 1.000 30.18148  ? 93  VAL   H CG1 1 
ATOM   713  C  CG2 . VAL   A 1 93  ? 0.36700   16.10100 -10.22200 1.000 25.08215  ? 93  VAL   H CG2 1 
ATOM   714  N  N   . TYR   A 1 94  ? -0.04700  16.18900 -14.84900 1.000 30.20781  ? 94  TYR   H N   1 
ATOM   715  C  CA  . TYR   A 1 94  ? -0.58500  16.05300 -16.19700 1.000 34.34382  ? 94  TYR   H CA  1 
ATOM   716  C  C   . TYR   A 1 94  ? -1.08600  14.63100 -16.41100 1.000 31.01696  ? 94  TYR   H C   1 
ATOM   717  O  O   . TYR   A 1 94  ? -0.32100  13.66900 -16.27900 1.000 31.19976  ? 94  TYR   H O   1 
ATOM   718  C  CB  . TYR   A 1 94  ? 0.47000   16.42300 -17.23700 1.000 34.63473  ? 94  TYR   H CB  1 
ATOM   719  C  CG  . TYR   A 1 94  ? 0.69100   17.91300 -17.35300 1.000 39.81230  ? 94  TYR   H CG  1 
ATOM   720  C  CD1 . TYR   A 1 94  ? 1.41800   18.60400 -16.39200 1.000 34.47560  ? 94  TYR   H CD1 1 
ATOM   721  C  CD2 . TYR   A 1 94  ? 0.16300   18.63100 -18.41700 1.000 38.36587  ? 94  TYR   H CD2 1 
ATOM   722  C  CE1 . TYR   A 1 94  ? 1.61900   19.96700 -16.49200 1.000 36.46899  ? 94  TYR   H CE1 1 
ATOM   723  C  CE2 . TYR   A 1 94  ? 0.35900   19.99400 -18.52600 1.000 35.12872  ? 94  TYR   H CE2 1 
ATOM   724  C  CZ  . TYR   A 1 94  ? 1.08700   20.65600 -17.56100 1.000 34.05359  ? 94  TYR   H CZ  1 
ATOM   725  O  OH  . TYR   A 1 94  ? 1.28500   22.01200 -17.66500 1.000 38.16774  ? 94  TYR   H OH  1 
ATOM   726  N  N   . TYR   A 1 95  ? -2.36600  14.50500 -16.74800 1.000 33.85288  ? 95  TYR   H N   1 
ATOM   727  C  CA  . TYR   A 1 95  ? -3.01000  13.21600 -16.94200 1.000 31.68869  ? 95  TYR   H CA  1 
ATOM   728  C  C   . TYR   A 1 95  ? -3.22500  12.94600 -18.42200 1.000 33.22605  ? 95  TYR   H C   1 
ATOM   729  O  O   . TYR   A 1 95  ? -3.53900  13.85600 -19.19600 1.000 32.72935  ? 95  TYR   H O   1 
ATOM   730  C  CB  . TYR   A 1 95  ? -4.35800  13.15400 -16.21800 1.000 30.76763  ? 95  TYR   H CB  1 
ATOM   731  C  CG  . TYR   A 1 95  ? -4.24700  13.06600 -14.71700 1.000 35.99324  ? 95  TYR   H CG  1 
ATOM   732  C  CD1 . TYR   A 1 95  ? -3.89000  11.87500 -14.09900 1.000 33.99647  ? 95  TYR   H CD1 1 
ATOM   733  C  CD2 . TYR   A 1 95  ? -4.50300  14.17000 -13.91600 1.000 29.06343  ? 95  TYR   H CD2 1 
ATOM   734  C  CE1 . TYR   A 1 95  ? -3.78800  11.78800 -12.72400 1.000 33.28464  ? 95  TYR   H CE1 1 
ATOM   735  C  CE2 . TYR   A 1 95  ? -4.40400  14.09400 -12.54300 1.000 34.26398  ? 95  TYR   H CE2 1 
ATOM   736  C  CZ  . TYR   A 1 95  ? -4.04600  12.90000 -11.95100 1.000 37.82630  ? 95  TYR   H CZ  1 
ATOM   737  O  OH  . TYR   A 1 95  ? -3.94600  12.81600 -10.58100 1.000 42.89479  ? 95  TYR   H OH  1 
ATOM   738  N  N   . CYS   A 1 96  ? -3.05200  11.68700 -18.79900 1.000 40.21797  ? 96  CYS   H N   1 
ATOM   739  C  CA  . CYS   A 1 96  ? -3.40900  11.18000 -20.11400 1.000 34.44695  ? 96  CYS   H CA  1 
ATOM   740  C  C   . CYS   A 1 96  ? -4.67800  10.35100 -19.96500 1.000 32.69304  ? 96  CYS   H C   1 
ATOM   741  O  O   . CYS   A 1 96  ? -4.75800  9.49600  -19.07800 1.000 40.83087  ? 96  CYS   H O   1 
ATOM   742  C  CB  . CYS   A 1 96  ? -2.25200  10.35500 -20.67700 1.000 35.49140  ? 96  CYS   H CB  1 
ATOM   743  S  SG  . CYS   A 1 96  ? -2.61000  9.25000  -22.03400 1.000 64.91522  ? 96  CYS   H SG  1 
ATOM   744  N  N   . ALA   A 1 97  ? -5.67900  10.62500 -20.80300 1.000 32.25878  ? 97  ALA   H N   1 
ATOM   745  C  CA  . ALA   A 1 97  ? -7.02200  10.11900 -20.55500 1.000 33.58092  ? 97  ALA   H CA  1 
ATOM   746  C  C   . ALA   A 1 97  ? -7.69000  9.66700  -21.84500 1.000 31.15798  ? 97  ALA   H C   1 
ATOM   747  O  O   . ALA   A 1 97  ? -7.40500  10.18100 -22.93000 1.000 31.31841  ? 97  ALA   H O   1 
ATOM   748  C  CB  . ALA   A 1 97  ? -7.88900  11.18100 -19.87300 1.000 32.06472  ? 97  ALA   H CB  1 
ATOM   749  N  N   . ARG   A 1 98  ? -8.61300  8.71400  -21.70000 1.000 26.79993  ? 98  ARG   H N   1 
ATOM   750  C  CA  . ARG   A 1 98  ? -9.34300  8.10900  -22.80600 1.000 29.69234  ? 98  ARG   H CA  1 
ATOM   751  C  C   . ARG   A 1 98  ? -10.83900 8.17100  -22.52600 1.000 31.10531  ? 98  ARG   H C   1 
ATOM   752  O  O   . ARG   A 1 98  ? -11.27000 8.00400  -21.38100 1.000 30.49819  ? 98  ARG   H O   1 
ATOM   753  C  CB  . ARG   A 1 98  ? -8.90700  6.65100  -23.01300 1.000 27.76875  ? 98  ARG   H CB  1 
ATOM   754  C  CG  . ARG   A 1 98  ? -9.38900  6.01300  -24.30500 1.000 29.55683  ? 98  ARG   H CG  1 
ATOM   755  C  CD  . ARG   A 1 98  ? -9.65500  4.52800  -24.10800 1.000 31.17264  ? 98  ARG   H CD  1 
ATOM   756  N  NE  . ARG   A 1 98  ? -11.03000 4.27100  -23.69200 1.000 37.61934  ? 98  ARG   H NE  1 
ATOM   757  C  CZ  . ARG   A 1 98  ? -11.53700 3.05800  -23.49500 1.000 35.97387  ? 98  ARG   H CZ  1 
ATOM   758  N  NH1 . ARG   A 1 98  ? -10.77900 1.98600  -23.67600 1.000 36.60972  ? 98  ARG   H NH1 1 
ATOM   759  N  NH2 . ARG   A 1 98  ? -12.80000 2.91600  -23.11800 1.000 37.93338  ? 98  ARG   H NH2 1 
ATOM   760  N  N   . ASP   A 1 99  ? -11.62900 8.39700  -23.57500 1.000 33.49651  ? 99  ASP   H N   1 
ATOM   761  C  CA  . ASP   A 1 99  ? -13.07100 8.51900  -23.41900 1.000 33.07781  ? 99  ASP   H CA  1 
ATOM   762  C  C   . ASP   A 1 99  ? -13.71900 7.14300  -23.25600 1.000 35.77599  ? 99  ASP   H C   1 
ATOM   763  O  O   . ASP   A 1 99  ? -13.12600 6.12300  -23.61500 1.000 33.18886  ? 99  ASP   H O   1 
ATOM   764  C  CB  . ASP   A 1 99  ? -13.66200 9.28200  -24.60800 1.000 35.14701  ? 99  ASP   H CB  1 
ATOM   765  C  CG  . ASP   A 1 99  ? -13.57100 8.51700  -25.91000 1.000 41.47725  ? 99  ASP   H CG  1 
ATOM   766  O  OD1 . ASP   A 1 99  ? -12.83500 8.97800  -26.80700 1.000 43.78903  ? 99  ASP   H OD1 1 
ATOM   767  O  OD2 . ASP   A 1 99  ? -14.25300 7.48100  -26.05700 1.000 42.12568  ? 99  ASP   H OD2 1 
ATOM   768  N  N   . PRO   A 1 100 ? -14.94000 7.08400  -22.70800 1.000 41.11102  ? 100 PRO   H N   1 
ATOM   769  C  CA  . PRO   A 1 100 ? -15.54500 5.77900  -22.38900 1.000 40.56299  ? 100 PRO   H CA  1 
ATOM   770  C  C   . PRO   A 1 100 ? -15.88500 4.92100  -23.59700 1.000 41.39423  ? 100 PRO   H C   1 
ATOM   771  O  O   . PRO   A 1 100 ? -16.44100 3.83200  -23.41600 1.000 48.51170  ? 100 PRO   H O   1 
ATOM   772  C  CB  . PRO   A 1 100 ? -16.82400 6.16100  -21.62000 1.000 37.00792  ? 100 PRO   H CB  1 
ATOM   773  C  CG  . PRO   A 1 100 ? -16.63000 7.58100  -21.20700 1.000 34.31603  ? 100 PRO   H CG  1 
ATOM   774  C  CD  . PRO   A 1 100 ? -15.81100 8.19500  -22.28800 1.000 37.28129  ? 100 PRO   H CD  1 
ATOM   775  N  N   . GLY   A 1 101 ? -15.58100 5.36100  -24.81500 1.000 38.47650  ? 101 GLY   H N   1 
ATOM   776  C  CA  . GLY   A 1 101 ? -15.86900 4.56200  -25.98800 1.000 34.35930  ? 101 GLY   H CA  1 
ATOM   777  C  C   . GLY   A 1 101 ? -17.16700 4.94600  -26.66500 1.000 38.61137  ? 101 GLY   H C   1 
ATOM   778  O  O   . GLY   A 1 101 ? -18.15000 5.28100  -25.99500 1.000 31.89466  ? 101 GLY   H O   1 
ATOM   779  N  N   . GLY   A 1 102 ? -17.17800 4.90300  -27.99500 1.000 40.12098  ? 102 GLY   H N   1 
ATOM   780  C  CA  . GLY   A 1 102 ? -18.37200 5.24600  -28.74900 1.000 35.70206  ? 102 GLY   H CA  1 
ATOM   781  C  C   . GLY   A 1 102 ? -18.83400 6.67200  -28.55800 1.000 37.04757  ? 102 GLY   H C   1 
ATOM   782  O  O   . GLY   A 1 102 ? -20.04000 6.93600  -28.59400 1.000 33.80502  ? 102 GLY   H O   1 
ATOM   783  N  N   . MET   A 1 103 ? -17.89900 7.61100  -28.35800 1.000 38.92068  ? 103 MET   H N   1 
ATOM   784  C  CA  . MET   A 1 103 ? -18.28800 8.98700  -28.09400 1.000 36.81256  ? 103 MET   H CA  1 
ATOM   785  C  C   . MET   A 1 103 ? -18.43400 9.76800  -29.39700 1.000 38.80574  ? 103 MET   H C   1 
ATOM   786  O  O   . MET   A 1 103 ? -17.77200 9.45900  -30.39300 1.000 36.25300  ? 103 MET   H O   1 
ATOM   787  C  CB  . MET   A 1 103 ? -17.26100 9.66200  -27.18900 1.000 36.49529  ? 103 MET   H CB  1 
ATOM   788  C  CG  . MET   A 1 103 ? -17.12900 8.99400  -25.82700 1.000 39.27201  ? 103 MET   H CG  1 
ATOM   789  S  SD  . MET   A 1 103 ? -18.70500 8.83200  -24.95800 1.000 40.64970  ? 103 MET   H SD  1 
ATOM   790  C  CE  . MET   A 1 103 ? -19.00800 10.52600 -24.45900 1.000 44.89135  ? 103 MET   H CE  1 
ATOM   791  N  N   . PRO   A 1 104 ? -19.30300 10.78700 -29.41700 1.000 42.48014  ? 104 PRO   H N   1 
ATOM   792  C  CA  . PRO   A 1 104 ? -19.64700 11.43200 -30.69400 1.000 38.43707  ? 104 PRO   H CA  1 
ATOM   793  C  C   . PRO   A 1 104 ? -18.58500 12.36600 -31.25000 1.000 37.31897  ? 104 PRO   H C   1 
ATOM   794  O  O   . PRO   A 1 104 ? -18.57800 12.59600 -32.46700 1.000 43.19209  ? 104 PRO   H O   1 
ATOM   795  C  CB  . PRO   A 1 104 ? -20.92900 12.20500 -30.35700 1.000 35.67712  ? 104 PRO   H CB  1 
ATOM   796  C  CG  . PRO   A 1 104 ? -20.79200 12.51500 -28.90700 1.000 40.00274  ? 104 PRO   H CG  1 
ATOM   797  C  CD  . PRO   A 1 104 ? -20.10000 11.32400 -28.29900 1.000 41.27899  ? 104 PRO   H CD  1 
ATOM   798  N  N   . THR   A 1 105 ? -17.69900 12.91800 -30.42300 1.000 36.07028  ? 105 THR   H N   1 
ATOM   799  C  CA  . THR   A 1 105 ? -16.69900 13.85800 -30.91000 1.000 33.51303  ? 105 THR   H CA  1 
ATOM   800  C  C   . THR   A 1 105 ? -15.39000 13.64200 -30.15900 1.000 32.70496  ? 105 THR   H C   1 
ATOM   801  O  O   . THR   A 1 105 ? -15.28500 12.78900 -29.27100 1.000 38.61793  ? 105 THR   H O   1 
ATOM   802  C  CB  . THR   A 1 105 ? -17.18900 15.30600 -30.78400 1.000 35.98131  ? 105 THR   H CB  1 
ATOM   803  O  OG1 . THR   A 1 105 ? -16.27900 16.18300 -31.46100 1.000 42.56775  ? 105 THR   H OG1 1 
ATOM   804  C  CG2 . THR   A 1 105 ? -17.29500 15.71100 -29.32400 1.000 34.84299  ? 105 THR   H CG2 1 
ATOM   805  N  N   . THR   A 1 106 ? -14.38400 14.44200 -30.52200 1.000 29.46995  ? 106 THR   H N   1 
ATOM   806  C  CA  . THR   A 1 106 ? -13.02200 14.19300 -30.05800 1.000 32.59163  ? 106 THR   H CA  1 
ATOM   807  C  C   . THR   A 1 106 ? -12.86600 14.49200 -28.57100 1.000 33.61479  ? 106 THR   H C   1 
ATOM   808  O  O   . THR   A 1 106 ? -12.22600 13.72400 -27.84300 1.000 42.57766  ? 106 THR   H O   1 
ATOM   809  C  CB  . THR   A 1 106 ? -12.03500 15.02100 -30.88200 1.000 31.84405  ? 106 THR   H CB  1 
ATOM   810  O  OG1 . THR   A 1 106 ? -12.13700 14.65100 -32.26300 1.000 31.52895  ? 106 THR   H OG1 1 
ATOM   811  C  CG2 . THR   A 1 106 ? -10.60900 14.78700 -30.40800 1.000 28.84981  ? 106 THR   H CG2 1 
ATOM   812  N  N   . VAL   A 1 107 ? -13.43600 15.59600 -28.09800 1.000 33.88692  ? 107 VAL   H N   1 
ATOM   813  C  CA  . VAL   A 1 107 ? -13.30600 16.01300 -26.70600 1.000 37.31572  ? 107 VAL   H CA  1 
ATOM   814  C  C   . VAL   A 1 107 ? -14.63600 15.75800 -26.01100 1.000 34.68979  ? 107 VAL   H C   1 
ATOM   815  O  O   . VAL   A 1 107 ? -15.66500 16.32500 -26.39800 1.000 37.99594  ? 107 VAL   H O   1 
ATOM   816  C  CB  . VAL   A 1 107 ? -12.89300 17.48700 -26.59000 1.000 32.69241  ? 107 VAL   H CB  1 
ATOM   817  C  CG1 . VAL   A 1 107 ? -12.42600 17.79600 -25.17600 1.000 36.75295  ? 107 VAL   H CG1 1 
ATOM   818  C  CG2 . VAL   A 1 107 ? -11.80700 17.81600 -27.60400 1.000 24.89023  ? 107 VAL   H CG2 1 
ATOM   819  N  N   . THR   A 1 108 ? -14.61400 14.90900 -24.98100 1.000 34.88873  ? 108 THR   H N   1 
ATOM   820  C  CA  . THR   A 1 108 ? -15.82800 14.53500 -24.26400 1.000 39.39457  ? 108 THR   H CA  1 
ATOM   821  C  C   . THR   A 1 108 ? -15.56100 14.36100 -22.77300 1.000 40.82381  ? 108 THR   H C   1 
ATOM   822  O  O   . THR   A 1 108 ? -15.24300 15.32600 -22.07100 1.000 40.92068  ? 108 THR   H O   1 
ATOM   823  C  CB  . THR   A 1 108 ? -16.41200 13.23800 -24.83200 1.000 37.09516  ? 108 THR   H CB  1 
ATOM   824  O  OG1 . THR   A 1 108 ? -15.34700 12.33400 -25.15100 1.000 41.75557  ? 108 THR   H OG1 1 
ATOM   825  C  CG2 . THR   A 1 108 ? -17.23100 13.51600 -26.08300 1.000 35.91124  ? 108 THR   H CG2 1 
ATOM   826  N  N   . THR   A 1 109 ? -15.70600 13.13300 -22.28300 1.000 41.53096  ? 109 THR   H N   1 
ATOM   827  C  CA  . THR   A 1 109 ? -15.37600 12.78100 -20.91200 1.000 38.06418  ? 109 THR   H CA  1 
ATOM   828  C  C   . THR   A 1 109 ? -14.43600 11.58700 -20.93400 1.000 35.08775  ? 109 THR   H C   1 
ATOM   829  O  O   . THR   A 1 109 ? -14.17000 11.00600 -21.98700 1.000 39.97161  ? 109 THR   H O   1 
ATOM   830  C  CB  . THR   A 1 109 ? -16.62600 12.47800 -20.08500 1.000 38.39866  ? 109 THR   H CB  1 
ATOM   831  O  OG1 . THR   A 1 109 ? -17.58900 11.79800 -20.89900 1.000 40.44524  ? 109 THR   H OG1 1 
ATOM   832  C  CG2 . THR   A 1 109 ? -17.21300 13.77200 -19.59700 1.000 43.08257  ? 109 THR   H CG2 1 
ATOM   833  N  N   . TRP   A 1 110 ? -13.92000 11.22200 -19.76400 1.000 33.86798  ? 110 TRP   H N   1 
ATOM   834  C  CA  . TRP   A 1 110 ? -12.75000 10.35200 -19.70300 1.000 36.55406  ? 110 TRP   H CA  1 
ATOM   835  C  C   . TRP   A 1 110 ? -12.94500 9.27800  -18.64300 1.000 34.07669  ? 110 TRP   H C   1 
ATOM   836  O  O   . TRP   A 1 110 ? -12.93700 9.56500  -17.44200 1.000 34.11794  ? 110 TRP   H O   1 
ATOM   837  C  CB  . TRP   A 1 110 ? -11.49800 11.18900 -19.45500 1.000 27.72251  ? 110 TRP   H CB  1 
ATOM   838  C  CG  . TRP   A 1 110 ? -11.35200 12.18000 -20.56300 1.000 34.34567  ? 110 TRP   H CG  1 
ATOM   839  C  CD1 . TRP   A 1 110 ? -11.11700 11.89800 -21.87500 1.000 36.52622  ? 110 TRP   H CD1 1 
ATOM   840  C  CD2 . TRP   A 1 110 ? -11.52000 13.60300 -20.48300 1.000 39.44838  ? 110 TRP   H CD2 1 
ATOM   841  N  NE1 . TRP   A 1 110 ? -11.09500 13.05500 -22.61100 1.000 37.66862  ? 110 TRP   H NE1 1 
ATOM   842  C  CE2 . TRP   A 1 110 ? -11.33500 14.11600 -21.78200 1.000 34.26214  ? 110 TRP   H CE2 1 
ATOM   843  C  CE3 . TRP   A 1 110 ? -11.78700 14.49200 -19.43800 1.000 39.39332  ? 110 TRP   H CE3 1 
ATOM   844  C  CZ2 . TRP   A 1 110 ? -11.40900 15.47800 -22.06500 1.000 37.60120  ? 110 TRP   H CZ2 1 
ATOM   845  C  CZ3 . TRP   A 1 110 ? -11.86000 15.84500 -19.72200 1.000 36.84367  ? 110 TRP   H CZ3 1 
ATOM   846  C  CH2 . TRP   A 1 110 ? -11.67200 16.32400 -21.02500 1.000 39.26831  ? 110 TRP   H CH2 1 
ATOM   847  N  N   . LEU   A 1 111 ? -13.11400 8.03700  -19.10600 1.000 31.96514  ? 111 LEU   H N   1 
ATOM   848  C  CA  . LEU   A 1 111 ? -13.33400 6.90100  -18.22100 1.000 33.32199  ? 111 LEU   H CA  1 
ATOM   849  C  C   . LEU   A 1 111 ? -12.02100 6.34800  -17.67900 1.000 35.94802  ? 111 LEU   H C   1 
ATOM   850  O  O   . LEU   A 1 111 ? -11.96100 5.90300  -16.52700 1.000 40.18501  ? 111 LEU   H O   1 
ATOM   851  C  CB  . LEU   A 1 111 ? -14.10400 5.81000  -18.96800 1.000 28.71488  ? 111 LEU   H CB  1 
ATOM   852  C  CG  . LEU   A 1 111 ? -14.25100 4.43700  -18.31200 1.000 30.94932  ? 111 LEU   H CG  1 
ATOM   853  C  CD1 . LEU   A 1 111 ? -14.98900 4.54700  -16.98800 1.000 34.48502  ? 111 LEU   H CD1 1 
ATOM   854  C  CD2 . LEU   A 1 111 ? -14.96100 3.46900  -19.24900 1.000 37.84215  ? 111 LEU   H CD2 1 
ATOM   855  N  N   . TYR   A 1 112 ? -10.96500 6.36900  -18.48500 1.000 33.32026  ? 112 TYR   H N   1 
ATOM   856  C  CA  . TYR   A 1 112 ? -9.67600  5.80900  -18.10700 1.000 30.06800  ? 112 TYR   H CA  1 
ATOM   857  C  C   . TYR   A 1 112 ? -8.65200  6.92400  -17.96500 1.000 34.19260  ? 112 TYR   H C   1 
ATOM   858  O  O   . TYR   A 1 112 ? -8.53300  7.78100  -18.84700 1.000 32.18310  ? 112 TYR   H O   1 
ATOM   859  C  CB  . TYR   A 1 112 ? -9.20400  4.78100  -19.13700 1.000 30.57383  ? 112 TYR   H CB  1 
ATOM   860  C  CG  . TYR   A 1 112 ? -10.01900 3.50900  -19.12900 1.000 32.50514  ? 112 TYR   H CG  1 
ATOM   861  C  CD1 . TYR   A 1 112 ? -9.90300  2.59400  -18.09100 1.000 33.02085  ? 112 TYR   H CD1 1 
ATOM   862  C  CD2 . TYR   A 1 112 ? -10.90900 3.22700  -20.15500 1.000 31.97131  ? 112 TYR   H CD2 1 
ATOM   863  C  CE1 . TYR   A 1 112 ? -10.64800 1.43000  -18.07800 1.000 30.98670  ? 112 TYR   H CE1 1 
ATOM   864  C  CE2 . TYR   A 1 112 ? -11.65900 2.06700  -20.15200 1.000 36.61772  ? 112 TYR   H CE2 1 
ATOM   865  C  CZ  . TYR   A 1 112 ? -11.52500 1.17200  -19.11100 1.000 38.22439  ? 112 TYR   H CZ  1 
ATOM   866  O  OH  . TYR   A 1 112 ? -12.27100 0.01500  -19.10400 1.000 33.58915  ? 112 TYR   H OH  1 
ATOM   867  N  N   . TRP   A 1 113 ? -7.91900  6.90800  -16.85400 1.000 36.08683  ? 113 TRP   H N   1 
ATOM   868  C  CA  . TRP   A 1 113 ? -6.88500  7.89100  -16.57600 1.000 30.36111  ? 113 TRP   H CA  1 
ATOM   869  C  C   . TRP   A 1 113 ? -5.58100  7.18200  -16.25300 1.000 34.36234  ? 113 TRP   H C   1 
ATOM   870  O  O   . TRP   A 1 113 ? -5.57500  6.05300  -15.75300 1.000 35.54848  ? 113 TRP   H O   1 
ATOM   871  C  CB  . TRP   A 1 113 ? -7.26100  8.80300  -15.39900 1.000 28.70706  ? 113 TRP   H CB  1 
ATOM   872  C  CG  . TRP   A 1 113 ? -8.54700  9.54800  -15.56600 1.000 29.91156  ? 113 TRP   H CG  1 
ATOM   873  C  CD1 . TRP   A 1 113 ? -9.79800  9.01300  -15.67500 1.000 29.81476  ? 113 TRP   H CD1 1 
ATOM   874  C  CD2 . TRP   A 1 113 ? -8.71200  10.96900 -15.62000 1.000 29.44550  ? 113 TRP   H CD2 1 
ATOM   875  N  NE1 . TRP   A 1 113 ? -10.73000 10.01300 -15.80400 1.000 26.49234  ? 113 TRP   H NE1 1 
ATOM   876  C  CE2 . TRP   A 1 113 ? -10.09000 11.22400 -15.77200 1.000 33.31222  ? 113 TRP   H CE2 1 
ATOM   877  C  CE3 . TRP   A 1 113 ? -7.82900  12.05200 -15.55800 1.000 27.53762  ? 113 TRP   H CE3 1 
ATOM   878  C  CZ2 . TRP   A 1 113 ? -10.60400 12.51600 -15.86400 1.000 33.26397  ? 113 TRP   H CZ2 1 
ATOM   879  C  CZ3 . TRP   A 1 113 ? -8.34300  13.33400 -15.65000 1.000 28.90550  ? 113 TRP   H CZ3 1 
ATOM   880  C  CH2 . TRP   A 1 113 ? -9.71700  13.55400 -15.80100 1.000 27.09671  ? 113 TRP   H CH2 1 
ATOM   881  N  N   . GLY   A 1 114 ? -4.47200  7.85600  -16.54200 1.000 31.85741  ? 114 GLY   H N   1 
ATOM   882  C  CA  . GLY   A 1 114 ? -3.17800  7.39300  -16.10000 1.000 34.77412  ? 114 GLY   H CA  1 
ATOM   883  C  C   . GLY   A 1 114 ? -2.93600  7.75900  -14.65100 1.000 32.58977  ? 114 GLY   H C   1 
ATOM   884  O  O   . GLY   A 1 114 ? -3.77400  8.35900  -13.97700 1.000 35.38545  ? 114 GLY   H O   1 
ATOM   885  N  N   . GLN   A 1 115 ? -1.75700  7.37900  -14.15800 1.000 35.62833  ? 115 GLN   H N   1 
ATOM   886  C  CA  . GLN   A 1 115 ? -1.38000  7.77100  -12.80600 1.000 33.24929  ? 115 GLN   H CA  1 
ATOM   887  C  C   . GLN   A 1 115 ? -1.01200  9.24600  -12.72700 1.000 35.37524  ? 115 GLN   H C   1 
ATOM   888  O  O   . GLN   A 1 115 ? -0.99700  9.81200  -11.62900 1.000 41.48823  ? 115 GLN   H O   1 
ATOM   889  C  CB  . GLN   A 1 115 ? -0.21600  6.91000  -12.30900 1.000 30.32712  ? 115 GLN   H CB  1 
ATOM   890  N  N   . GLY   A 1 116 ? -0.72900  9.87700  -13.86300 1.000 37.93518  ? 116 GLY   H N   1 
ATOM   891  C  CA  . GLY   A 1 116 ? -0.35700  11.27600 -13.88800 1.000 36.23962  ? 116 GLY   H CA  1 
ATOM   892  C  C   . GLY   A 1 116 ? 1.11900   11.49200 -13.63600 1.000 33.98186  ? 116 GLY   H C   1 
ATOM   893  O  O   . GLY   A 1 116 ? 1.73100   10.77200 -12.84100 1.000 37.76451  ? 116 GLY   H O   1 
ATOM   894  N  N   . THR   A 1 117 ? 1.70400   12.47300 -14.31500 1.000 27.93439  ? 117 THR   H N   1 
ATOM   895  C  CA  . THR   A 1 117 ? 3.09000   12.86200 -14.10400 1.000 25.30328  ? 117 THR   H CA  1 
ATOM   896  C  C   . THR   A 1 117 ? 3.13700   14.34200 -13.74600 1.000 29.63132  ? 117 THR   H C   1 
ATOM   897  O  O   . THR   A 1 117 ? 2.34300   15.14000 -14.25400 1.000 35.29857  ? 117 THR   H O   1 
ATOM   898  C  CB  . THR   A 1 117 ? 3.94900   12.56300 -15.34300 1.000 28.83673  ? 117 THR   H CB  1 
ATOM   899  O  OG1 . THR   A 1 117 ? 5.31700   12.88000 -15.06500 1.000 35.47259  ? 117 THR   H OG1 1 
ATOM   900  C  CG2 . THR   A 1 117 ? 3.47400   13.35900 -16.55100 1.000 33.35159  ? 117 THR   H CG2 1 
ATOM   901  N  N   . LEU   A 1 118 ? 4.05500   14.70200 -12.85300 1.000 32.39964  ? 118 LEU   H N   1 
ATOM   902  C  CA  . LEU   A 1 118 ? 4.06700   16.01800 -12.22700 1.000 32.72198  ? 118 LEU   H CA  1 
ATOM   903  C  C   . LEU   A 1 118 ? 5.14400   16.88700 -12.86600 1.000 33.36801  ? 118 LEU   H C   1 
ATOM   904  O  O   . LEU   A 1 118 ? 6.31700   16.50100 -12.90400 1.000 37.12215  ? 118 LEU   H O   1 
ATOM   905  C  CB  . LEU   A 1 118 ? 4.29900   15.89200 -10.72200 1.000 34.53664  ? 118 LEU   H CB  1 
ATOM   906  C  CG  . LEU   A 1 118 ? 4.71500   17.15100 -9.96000  1.000 38.87331  ? 118 LEU   H CG  1 
ATOM   907  C  CD1 . LEU   A 1 118 ? 3.57800   18.16000 -9.92700  1.000 35.66576  ? 118 LEU   H CD1 1 
ATOM   908  C  CD2 . LEU   A 1 118 ? 5.15400   16.78500 -8.55100  1.000 39.06295  ? 118 LEU   H CD2 1 
ATOM   909  N  N   . VAL   A 1 119 ? 4.74300   18.06000 -13.35100 1.000 38.86270  ? 119 VAL   H N   1 
ATOM   910  C  CA  . VAL   A 1 119 ? 5.63900   19.00300 -14.01000 1.000 38.12724  ? 119 VAL   H CA  1 
ATOM   911  C  C   . VAL   A 1 119 ? 5.73200   20.24200 -13.13100 1.000 40.30828  ? 119 VAL   H C   1 
ATOM   912  O  O   . VAL   A 1 119 ? 4.75600   20.98800 -12.98400 1.000 39.15336  ? 119 VAL   H O   1 
ATOM   913  C  CB  . VAL   A 1 119 ? 5.15500   19.36200 -15.42100 1.000 31.68612  ? 119 VAL   H CB  1 
ATOM   914  C  CG1 . VAL   A 1 119 ? 6.12100   20.33300 -16.08400 1.000 38.27874  ? 119 VAL   H CG1 1 
ATOM   915  C  CG2 . VAL   A 1 119 ? 4.99100   18.10700 -16.26100 1.000 29.58676  ? 119 VAL   H CG2 1 
ATOM   916  N  N   . THR   A 1 120 ? 6.90600   20.46700 -12.55000 1.000 41.66812  ? 120 THR   H N   1 
ATOM   917  C  CA  . THR   A 1 120 ? 7.15800   21.62900 -11.70800 1.000 37.14452  ? 120 THR   H CA  1 
ATOM   918  C  C   . THR   A 1 120 ? 7.86900   22.69300 -12.53300 1.000 41.95320  ? 120 THR   H C   1 
ATOM   919  O  O   . THR   A 1 120 ? 8.95900   22.44700 -13.06200 1.000 41.96261  ? 120 THR   H O   1 
ATOM   920  C  CB  . THR   A 1 120 ? 7.99700   21.25200 -10.48600 1.000 39.30470  ? 120 THR   H CB  1 
ATOM   921  O  OG1 . THR   A 1 120 ? 7.33900   20.21300 -9.74900  1.000 42.80865  ? 120 THR   H OG1 1 
ATOM   922  C  CG2 . THR   A 1 120 ? 8.19900   22.46500 -9.58100  1.000 36.05547  ? 120 THR   H CG2 1 
ATOM   923  N  N   . VAL   A 1 121 ? 7.24800   23.86300 -12.65100 1.000 40.60821  ? 121 VAL   H N   1 
ATOM   924  C  CA  . VAL   A 1 121 ? 7.85800   25.02400 -13.28700 1.000 38.67935  ? 121 VAL   H CA  1 
ATOM   925  C  C   . VAL   A 1 121 ? 8.36800   25.93200 -12.17700 1.000 43.87404  ? 121 VAL   H C   1 
ATOM   926  O  O   . VAL   A 1 121 ? 7.58000   26.53100 -11.43700 1.000 44.02343  ? 121 VAL   H O   1 
ATOM   927  C  CB  . VAL   A 1 121 ? 6.87400   25.76100 -14.20200 1.000 39.77158  ? 121 VAL   H CB  1 
ATOM   928  C  CG1 . VAL   A 1 121 ? 7.52500   27.01500 -14.75300 1.000 39.98448  ? 121 VAL   H CG1 1 
ATOM   929  C  CG2 . VAL   A 1 121 ? 6.42200   24.85000 -15.33600 1.000 40.01433  ? 121 VAL   H CG2 1 
ATOM   930  N  N   . SER   A 1 122 ? 9.69100   26.03300 -12.07300 1.000 42.50656  ? 122 SER   H N   1 
ATOM   931  C  CA  . SER   A 1 122 ? 10.38100  26.77000 -11.02400 1.000 41.85783  ? 122 SER   H CA  1 
ATOM   932  C  C   . SER   A 1 122 ? 11.86200  26.82200 -11.37000 1.000 46.72582  ? 122 SER   H C   1 
ATOM   933  O  O   . SER   A 1 122 ? 12.39700  25.87400 -11.95400 1.000 45.74287  ? 122 SER   H O   1 
ATOM   934  C  CB  . SER   A 1 122 ? 10.16900  26.10900 -9.65700  1.000 41.93124  ? 122 SER   H CB  1 
ATOM   935  O  OG  . SER   A 1 122 ? 10.87100  26.79000 -8.63500  1.000 38.78847  ? 122 SER   H OG  1 
ATOM   936  N  N   . SER   A 1 123 ? 12.50500  27.94700 -11.04900 1.000 53.21990  ? 123 SER   H N   1 
ATOM   937  C  CA  . SER   A 1 123 ? 13.94400  28.07600 -11.23100 1.000 57.13112  ? 123 SER   H CA  1 
ATOM   938  C  C   . SER   A 1 123 ? 14.70700  27.70300 -9.96600  1.000 55.07839  ? 123 SER   H C   1 
ATOM   939  O  O   . SER   A 1 123 ? 15.94500  27.71100 -9.96500  1.000 56.65781  ? 123 SER   H O   1 
ATOM   940  C  CB  . SER   A 1 123 ? 14.31200  29.50800 -11.66700 1.000 55.96331  ? 123 SER   H CB  1 
ATOM   941  O  OG  . SER   A 1 123 ? 15.55200  29.48500 -12.36300 1.000 60.43026  ? 123 SER   H OG  1 
ATOM   942  N  N   . ALA   A 1 124 ? 13.99500  27.42200 -8.87900  1.000 47.00217  ? 124 ALA   H N   1 
ATOM   943  C  CA  . ALA   A 1 124 ? 14.62200  26.79100 -7.73200  1.000 48.92697  ? 124 ALA   H CA  1 
ATOM   944  C  C   . ALA   A 1 124 ? 15.27000  25.47200 -8.15600  1.000 53.03541  ? 124 ALA   H C   1 
ATOM   945  O  O   . ALA   A 1 124 ? 14.86200  24.82400 -9.12600  1.000 53.96152  ? 124 ALA   H O   1 
ATOM   946  C  CB  . ALA   A 1 124 ? 13.60200  26.55600 -6.61600  1.000 42.53941  ? 124 ALA   H CB  1 
ATOM   947  N  N   . SER   A 1 125 ? 16.30100  25.07900 -7.42000  1.000 53.02018  ? 125 SER   H N   1 
ATOM   948  C  CA  . SER   A 1 125 ? 17.09500  23.90800 -7.76100  1.000 52.88566  ? 125 SER   H CA  1 
ATOM   949  C  C   . SER   A 1 125 ? 16.60800  22.68500 -6.99300  1.000 50.83516  ? 125 SER   H C   1 
ATOM   950  O  O   . SER   A 1 125 ? 16.21200  22.79000 -5.82700  1.000 52.70090  ? 125 SER   H O   1 
ATOM   951  C  CB  . SER   A 1 125 ? 18.57500  24.16400 -7.46900  1.000 52.14421  ? 125 SER   H CB  1 
ATOM   952  O  OG  . SER   A 1 125 ? 19.00000  25.37500 -8.07400  1.000 63.10853  ? 125 SER   H OG  1 
ATOM   953  N  N   . THR   A 1 126 ? 16.62000  21.52900 -7.66000  1.000 50.42325  ? 126 THR   H N   1 
ATOM   954  C  CA  . THR   A 1 126 ? 16.29200  20.27900 -6.98400  1.000 47.83616  ? 126 THR   H CA  1 
ATOM   955  C  C   . THR   A 1 126 ? 17.18700  20.10000 -5.76600  1.000 45.86335  ? 126 THR   H C   1 
ATOM   956  O  O   . THR   A 1 126 ? 18.41000  20.23800 -5.85500  1.000 47.35484  ? 126 THR   H O   1 
ATOM   957  C  CB  . THR   A 1 126 ? 16.46300  19.08000 -7.91700  1.000 47.78726  ? 126 THR   H CB  1 
ATOM   958  O  OG1 . THR   A 1 126 ? 17.81600  18.60700 -7.83200  1.000 53.86214  ? 126 THR   H OG1 1 
ATOM   959  C  CG2 . THR   A 1 126 ? 16.12100  19.45500 -9.36400  1.000 50.16545  ? 126 THR   H CG2 1 
ATOM   960  N  N   . LYS   A 1 127 ? 16.57900  19.78600 -4.62700  1.000 46.77668  ? 127 LYS   H N   1 
ATOM   961  C  CA  . LYS   A 1 127 ? 17.31300  19.69100 -3.37100  1.000 45.35416  ? 127 LYS   H CA  1 
ATOM   962  C  C   . LYS   A 1 127 ? 16.77800  18.51900 -2.56700  1.000 42.75584  ? 127 LYS   H C   1 
ATOM   963  O  O   . LYS   A 1 127 ? 15.58100  18.46500 -2.26800  1.000 45.05759  ? 127 LYS   H O   1 
ATOM   964  C  CB  . LYS   A 1 127 ? 17.19800  20.99200 -2.57300  1.000 43.58664  ? 127 LYS   H CB  1 
ATOM   965  C  CG  . LYS   A 1 127 ? 17.94800  20.98300 -1.25900  1.000 44.33999  ? 127 LYS   H CG  1 
ATOM   966  C  CD  . LYS   A 1 127 ? 17.28300  21.89700 -0.24300  1.000 51.39354  ? 127 LYS   H CD  1 
ATOM   967  C  CE  . LYS   A 1 127 ? 18.01400  21.86600 1.08900   1.000 50.93711  ? 127 LYS   H CE  1 
ATOM   968  N  NZ  . LYS   A 1 127 ? 18.14800  20.48000 1.61300   1.000 58.69667  ? 127 LYS   H NZ  1 
ATOM   969  N  N   . GLY   A 1 128 ? 17.66200  17.58500 -2.22400  1.000 51.85384  ? 128 GLY   H N   1 
ATOM   970  C  CA  . GLY   A 1 128 ? 17.30500  16.45500 -1.40100  1.000 47.62585  ? 128 GLY   H CA  1 
ATOM   971  C  C   . GLY   A 1 128 ? 16.92400  16.87400 0.00500   1.000 48.65112  ? 128 GLY   H C   1 
ATOM   972  O  O   . GLY   A 1 128 ? 17.27500  17.96200 0.47300   1.000 46.63383  ? 128 GLY   H O   1 
ATOM   973  N  N   . PRO   A 1 129 ? 16.19900  16.01300 0.70800   1.000 46.21056  ? 129 PRO   H N   1 
ATOM   974  C  CA  . PRO   A 1 129 ? 15.68000  16.37000 2.02800   1.000 48.37825  ? 129 PRO   H CA  1 
ATOM   975  C  C   . PRO   A 1 129 ? 16.69000  16.12100 3.14400   1.000 49.67532  ? 129 PRO   H C   1 
ATOM   976  O  O   . PRO   A 1 129 ? 17.73200  15.49000 2.95600   1.000 43.07861  ? 129 PRO   H O   1 
ATOM   977  C  CB  . PRO   A 1 129 ? 14.47100  15.44100 2.17300   1.000 46.00379  ? 129 PRO   H CB  1 
ATOM   978  C  CG  . PRO   A 1 129 ? 14.87600  14.21700 1.42900   1.000 45.04983  ? 129 PRO   H CG  1 
ATOM   979  C  CD  . PRO   A 1 129 ? 15.71200  14.69500 0.26300   1.000 49.02122  ? 129 PRO   H CD  1 
ATOM   980  N  N   . SER   A 1 130 ? 16.35000  16.63900 4.32200   1.000 50.92255  ? 130 SER   H N   1 
ATOM   981  C  CA  . SER   A 1 130 ? 17.10900  16.42300 5.55000   1.000 47.43807  ? 130 SER   H CA  1 
ATOM   982  C  C   . SER   A 1 130 ? 16.19000  15.71100 6.53200   1.000 44.65437  ? 130 SER   H C   1 
ATOM   983  O  O   . SER   A 1 130 ? 15.20200  16.29100 6.99500   1.000 47.65120  ? 130 SER   H O   1 
ATOM   984  C  CB  . SER   A 1 130 ? 17.61800  17.74500 6.12300   1.000 45.88923  ? 130 SER   H CB  1 
ATOM   985  O  OG  . SER   A 1 130 ? 18.85100  17.56700 6.79900   1.000 54.99775  ? 130 SER   H OG  1 
ATOM   986  N  N   . VAL   A 1 131 ? 16.50900  14.46100 6.84800   1.000 40.49296  ? 131 VAL   H N   1 
ATOM   987  C  CA  . VAL   A 1 131 ? 15.63000  13.59500 7.62600   1.000 38.56206  ? 131 VAL   H CA  1 
ATOM   988  C  C   . VAL   A 1 131 ? 16.12500  13.58100 9.06700   1.000 39.13167  ? 131 VAL   H C   1 
ATOM   989  O  O   . VAL   A 1 131 ? 17.18700  13.02600 9.36600   1.000 43.84782  ? 131 VAL   H O   1 
ATOM   990  C  CB  . VAL   A 1 131 ? 15.57300  12.17800 7.04100   1.000 38.16071  ? 131 VAL   H CB  1 
ATOM   991  C  CG1 . VAL   A 1 131 ? 14.78100  11.25800 7.95600   1.000 38.79908  ? 131 VAL   H CG1 1 
ATOM   992  C  CG2 . VAL   A 1 131 ? 14.96800  12.20600 5.64700   1.000 39.28432  ? 131 VAL   H CG2 1 
ATOM   993  N  N   . PHE   A 1 132 ? 15.35400  14.18800 9.96000   1.000 38.16260  ? 132 PHE   H N   1 
ATOM   994  C  CA  . PHE   A 1 132 ? 15.62900  14.18200 11.38500  1.000 37.92232  ? 132 PHE   H CA  1 
ATOM   995  C  C   . PHE   A 1 132 ? 14.61000  13.31400 12.11400  1.000 41.62833  ? 132 PHE   H C   1 
ATOM   996  O  O   . PHE   A 1 132 ? 13.45000  13.22700 11.69800  1.000 35.17585  ? 132 PHE   H O   1 
ATOM   997  C  CB  . PHE   A 1 132 ? 15.59500  15.60100 11.96200  1.000 38.51179  ? 132 PHE   H CB  1 
ATOM   998  C  CG  . PHE   A 1 132 ? 16.54400  16.54900 11.28900  1.000 45.35944  ? 132 PHE   H CG  1 
ATOM   999  C  CD1 . PHE   A 1 132 ? 17.91300  16.37000 11.39600  1.000 49.87646  ? 132 PHE   H CD1 1 
ATOM   1000 C  CD2 . PHE   A 1 132 ? 16.06800  17.61300 10.54200  1.000 39.37464  ? 132 PHE   H CD2 1 
ATOM   1001 C  CE1 . PHE   A 1 132 ? 18.79000  17.23700 10.77400  1.000 52.56534  ? 132 PHE   H CE1 1 
ATOM   1002 C  CE2 . PHE   A 1 132 ? 16.94000  18.48300 9.91600   1.000 43.00379  ? 132 PHE   H CE2 1 
ATOM   1003 C  CZ  . PHE   A 1 132 ? 18.30300  18.29600 10.03400  1.000 45.35966  ? 132 PHE   H CZ  1 
ATOM   1004 N  N   . PRO   A 1 133 ? 15.00800  12.65000 13.19800  1.000 43.38348  ? 133 PRO   H N   1 
ATOM   1005 C  CA  . PRO   A 1 133 ? 14.08700  11.74000 13.88500  1.000 34.54923  ? 133 PRO   H CA  1 
ATOM   1006 C  C   . PRO   A 1 133 ? 13.24700  12.43500 14.94500  1.000 35.88012  ? 133 PRO   H C   1 
ATOM   1007 O  O   . PRO   A 1 133 ? 13.68900  13.36200 15.62700  1.000 40.47544  ? 133 PRO   H O   1 
ATOM   1008 C  CB  . PRO   A 1 133 ? 15.04000  10.72200 14.52300  1.000 45.50772  ? 133 PRO   H CB  1 
ATOM   1009 C  CG  . PRO   A 1 133 ? 16.26000  11.52600 14.83900  1.000 41.09292  ? 133 PRO   H CG  1 
ATOM   1010 C  CD  . PRO   A 1 133 ? 16.35600  12.61900 13.79300  1.000 42.49914  ? 133 PRO   H CD  1 
ATOM   1011 N  N   . LEU   A 1 134 ? 12.00700  11.97000 15.07500  1.000 35.40883  ? 134 LEU   H N   1 
ATOM   1012 C  CA  . LEU   A 1 134 ? 11.10500  12.40700 16.13900  1.000 40.17698  ? 134 LEU   H CA  1 
ATOM   1013 C  C   . LEU   A 1 134 ? 11.12100  11.30900 17.19900  1.000 40.98787  ? 134 LEU   H C   1 
ATOM   1014 O  O   . LEU   A 1 134 ? 10.38000  10.32900 17.11700  1.000 37.61702  ? 134 LEU   H O   1 
ATOM   1015 C  CB  . LEU   A 1 134 ? 9.70400   12.67000 15.60000  1.000 39.65163  ? 134 LEU   H CB  1 
ATOM   1016 C  CG  . LEU   A 1 134 ? 9.61700   13.69500 14.46800  1.000 33.44132  ? 134 LEU   H CG  1 
ATOM   1017 C  CD1 . LEU   A 1 134 ? 8.41600   13.41300 13.58100  1.000 39.39277  ? 134 LEU   H CD1 1 
ATOM   1018 C  CD2 . LEU   A 1 134 ? 9.55700   15.10800 15.02200  1.000 30.69117  ? 134 LEU   H CD2 1 
ATOM   1019 N  N   . ALA   A 1 135 ? 11.98500  11.48200 18.19700  1.000 44.85582  ? 135 ALA   H N   1 
ATOM   1020 C  CA  . ALA   A 1 135 ? 12.22800  10.43000 19.17400  1.000 42.43901  ? 135 ALA   H CA  1 
ATOM   1021 C  C   . ALA   A 1 135 ? 10.99500  10.21300 20.04800  1.000 43.07034  ? 135 ALA   H C   1 
ATOM   1022 O  O   . ALA   A 1 135 ? 10.32700  11.17700 20.43500  1.000 41.59624  ? 135 ALA   H O   1 
ATOM   1023 C  CB  . ALA   A 1 135 ? 13.43300  10.77800 20.04800  1.000 41.44144  ? 135 ALA   H CB  1 
ATOM   1024 N  N   . PRO   A 1 136 ? 10.66500  8.96200  20.37000  1.000 47.87483  ? 136 PRO   H N   1 
ATOM   1025 C  CA  . PRO   A 1 136 ? 9.48700   8.70800  21.20800  1.000 47.44146  ? 136 PRO   H CA  1 
ATOM   1026 C  C   . PRO   A 1 136 ? 9.70000   9.17800  22.63800  1.000 54.49431  ? 136 PRO   H C   1 
ATOM   1027 O  O   . PRO   A 1 136 ? 10.79400  9.06700  23.19700  1.000 47.46603  ? 136 PRO   H O   1 
ATOM   1028 C  CB  . PRO   A 1 136 ? 9.31500   7.18500  21.13400  1.000 48.96716  ? 136 PRO   H CB  1 
ATOM   1029 C  CG  . PRO   A 1 136 ? 10.65300  6.66200  20.72900  1.000 45.68314  ? 136 PRO   H CG  1 
ATOM   1030 C  CD  . PRO   A 1 136 ? 11.27200  7.71800  19.86400  1.000 48.05931  ? 136 PRO   H CD  1 
ATOM   1031 N  N   . SER   A 1 137 ? 8.62800   9.70300  23.23000  1.000 63.90156  ? 137 SER   H N   1 
ATOM   1032 C  CA  . SER   A 1 137 ? 8.67800   10.28000 24.56800  1.000 69.44771  ? 137 SER   H CA  1 
ATOM   1033 C  C   . SER   A 1 137 ? 8.72300   9.20500  25.64700  1.000 72.28494  ? 137 SER   H C   1 
ATOM   1034 O  O   . SER   A 1 137 ? 9.35900   8.16000  25.47300  1.000 67.09251  ? 137 SER   H O   1 
ATOM   1035 C  CB  . SER   A 1 137 ? 7.47200   11.19700 24.78900  1.000 69.70243  ? 137 SER   H CB  1 
ATOM   1036 O  OG  . SER   A 1 137 ? 7.39700   11.63800 26.13400  1.000 62.59594  ? 137 SER   H OG  1 
ATOM   1037 N  N   . SER   A 1 138 ? 8.05800   9.46400  26.76900  1.000 75.23263  ? 138 SER   H N   1 
ATOM   1038 C  CA  . SER   A 1 138 ? 7.93200   8.50200  27.86300  1.000 78.96168  ? 138 SER   H CA  1 
ATOM   1039 C  C   . SER   A 1 138 ? 6.88500   8.98300  28.86000  1.000 76.14053  ? 138 SER   H C   1 
ATOM   1040 O  O   . SER   A 1 138 ? 6.36000   10.09200 28.73800  1.000 68.45849  ? 138 SER   H O   1 
ATOM   1041 C  CB  . SER   A 1 138 ? 9.27300   8.27600  28.57300  1.000 76.78773  ? 138 SER   H CB  1 
ATOM   1042 O  OG  . SER   A 1 138 ? 10.23400  7.70900  27.69800  1.000 79.04281  ? 138 SER   H OG  1 
ATOM   1043 N  N   . THR   A 1 141 ? 3.03300   9.40800  26.94800  1.000 65.52421  ? 141 THR   H N   1 
ATOM   1044 C  CA  . THR   A 1 141 ? 2.30100   8.15600  27.10100  1.000 65.28398  ? 141 THR   H CA  1 
ATOM   1045 C  C   . THR   A 1 141 ? 0.84400   8.43000  27.47200  1.000 66.57323  ? 141 THR   H C   1 
ATOM   1046 O  O   . THR   A 1 141 ? 0.51900   8.66600  28.63600  1.000 76.01544  ? 141 THR   H O   1 
ATOM   1047 C  CB  . THR   A 1 141 ? 2.95200   7.24600  28.17000  1.000 75.36370  ? 141 THR   H CB  1 
ATOM   1048 O  OG1 . THR   A 1 141 ? 4.28900   6.92200  27.77100  1.000 71.61475  ? 141 THR   H OG1 1 
ATOM   1049 C  CG2 . THR   A 1 141 ? 2.16000   5.95200  28.34100  1.000 66.42954  ? 141 THR   H CG2 1 
ATOM   1050 N  N   . SER   A 1 142 ? -0.03000  8.41200  26.47200  1.000 58.12839  ? 142 SER   H N   1 
ATOM   1051 C  CA  . SER   A 1 142 ? -1.45600  8.64600  26.66600  1.000 62.39304  ? 142 SER   H CA  1 
ATOM   1052 C  C   . SER   A 1 142 ? -2.19300  7.33300  26.43300  1.000 59.94172  ? 142 SER   H C   1 
ATOM   1053 O  O   . SER   A 1 142 ? -2.23900  6.83300  25.30400  1.000 58.85927  ? 142 SER   H O   1 
ATOM   1054 C  CB  . SER   A 1 142 ? -1.96000  9.74000  25.72800  1.000 65.04223  ? 142 SER   H CB  1 
ATOM   1055 O  OG  . SER   A 1 142 ? -0.97900  10.74800 25.54700  1.000 63.16223  ? 142 SER   H OG  1 
ATOM   1056 N  N   . GLY   A 1 143 ? -2.77300  6.78200  27.49700  1.000 59.26280  ? 143 GLY   H N   1 
ATOM   1057 C  CA  . GLY   A 1 143 ? -3.44000  5.49400  27.40000  1.000 49.15506  ? 143 GLY   H CA  1 
ATOM   1058 C  C   . GLY   A 1 143 ? -2.51000  4.35000  27.06300  1.000 46.99310  ? 143 GLY   H C   1 
ATOM   1059 O  O   . GLY   A 1 143 ? -2.94500  3.35800  26.46700  1.000 39.76185  ? 143 GLY   H O   1 
ATOM   1060 N  N   . GLY   A 1 144 ? -1.23800  4.45800  27.43900  1.000 51.27778  ? 144 GLY   H N   1 
ATOM   1061 C  CA  . GLY   A 1 144 ? -0.24600  3.47700  27.05600  1.000 44.52271  ? 144 GLY   H CA  1 
ATOM   1062 C  C   . GLY   A 1 144 ? 0.29100   3.63100  25.65300  1.000 44.86415  ? 144 GLY   H C   1 
ATOM   1063 O  O   . GLY   A 1 144 ? 1.00800   2.74200  25.18000  1.000 46.42131  ? 144 GLY   H O   1 
ATOM   1064 N  N   . THR   A 1 145 ? -0.02700  4.73100  24.97400  1.000 48.84127  ? 145 THR   H N   1 
ATOM   1065 C  CA  . THR   A 1 145 ? 0.36700   4.95100  23.59000  1.000 43.12327  ? 145 THR   H CA  1 
ATOM   1066 C  C   . THR   A 1 145 ? 1.58200   5.86700  23.52300  1.000 44.99777  ? 145 THR   H C   1 
ATOM   1067 O  O   . THR   A 1 145 ? 1.66900   6.85800  24.25400  1.000 51.73262  ? 145 THR   H O   1 
ATOM   1068 C  CB  . THR   A 1 145 ? -0.78300  5.56400  22.78500  1.000 41.04207  ? 145 THR   H CB  1 
ATOM   1069 O  OG1 . THR   A 1 145 ? -1.96100  4.76300  22.94300  1.000 48.61667  ? 145 THR   H OG1 1 
ATOM   1070 C  CG2 . THR   A 1 145 ? -0.43000  5.64300  21.30800  1.000 40.87019  ? 145 THR   H CG2 1 
ATOM   1071 N  N   . ALA   A 1 146 ? 2.51800   5.52700  22.64300  1.000 43.26145  ? 146 ALA   H N   1 
ATOM   1072 C  CA  . ALA   A 1 146 ? 3.67000   6.36500  22.35400  1.000 42.24355  ? 146 ALA   H CA  1 
ATOM   1073 C  C   . ALA   A 1 146 ? 3.65000   6.77000  20.88600  1.000 42.69011  ? 146 ALA   H C   1 
ATOM   1074 O  O   . ALA   A 1 146 ? 3.03200   6.11100  20.04600  1.000 36.88813  ? 146 ALA   H O   1 
ATOM   1075 C  CB  . ALA   A 1 146 ? 4.98400   5.64700  22.68700  1.000 36.33521  ? 146 ALA   H CB  1 
ATOM   1076 N  N   . ALA   A 1 147 ? 4.33300   7.87100  20.58300  1.000 45.13610  ? 147 ALA   H N   1 
ATOM   1077 C  CA  . ALA   A 1 147 ? 4.42900   8.37400  19.22200  1.000 39.15842  ? 147 ALA   H CA  1 
ATOM   1078 C  C   . ALA   A 1 147 ? 5.88800   8.58600  18.84900  1.000 40.42686  ? 147 ALA   H C   1 
ATOM   1079 O  O   . ALA   A 1 147 ? 6.73500   8.85000  19.70500  1.000 47.08484  ? 147 ALA   H O   1 
ATOM   1080 C  CB  . ALA   A 1 147 ? 3.64800   9.68200  19.04500  1.000 39.90585  ? 147 ALA   H CB  1 
ATOM   1081 N  N   . LEU   A 1 148 ? 6.16700   8.46500  17.55400  1.000 35.12467  ? 148 LEU   H N   1 
ATOM   1082 C  CA  . LEU   A 1 148 ? 7.50600   8.63800  17.00700  1.000 38.84555  ? 148 LEU   H CA  1 
ATOM   1083 C  C   . LEU   A 1 148 ? 7.37400   8.83600  15.50700  1.000 38.68825  ? 148 LEU   H C   1 
ATOM   1084 O  O   . LEU   A 1 148 ? 6.35800   8.47600  14.90700  1.000 37.28561  ? 148 LEU   H O   1 
ATOM   1085 C  CB  . LEU   A 1 148 ? 8.40800   7.43800  17.31500  1.000 46.10575  ? 148 LEU   H CB  1 
ATOM   1086 C  CG  . LEU   A 1 148 ? 7.88300   6.07400  16.86000  1.000 46.17150  ? 148 LEU   H CG  1 
ATOM   1087 C  CD1 . LEU   A 1 148 ? 8.53500   5.64400  15.55300  1.000 45.08527  ? 148 LEU   H CD1 1 
ATOM   1088 C  CD2 . LEU   A 1 148 ? 8.09800   5.02500  17.94000  1.000 48.50602  ? 148 LEU   H CD2 1 
ATOM   1089 N  N   . GLY   A 1 149 ? 8.41000   9.40300  14.90400  1.000 40.30544  ? 149 GLY   H N   1 
ATOM   1090 C  CA  . GLY   A 1 149 ? 8.35100   9.61900  13.47500  1.000 39.24687  ? 149 GLY   H CA  1 
ATOM   1091 C  C   . GLY   A 1 149 ? 9.63500   10.20200 12.93400  1.000 33.26146  ? 149 GLY   H C   1 
ATOM   1092 O  O   . GLY   A 1 149 ? 10.63800  10.31900 13.63900  1.000 40.01417  ? 149 GLY   H O   1 
ATOM   1093 N  N   . CYS   A 1 150 ? 9.58600   10.55500 11.65300  1.000 40.74685  ? 150 CYS   H N   1 
ATOM   1094 C  CA  . CYS   A 1 150 ? 10.70000  11.17900 10.95500  1.000 43.07893  ? 150 CYS   H CA  1 
ATOM   1095 C  C   . CYS   A 1 150 ? 10.25400  12.53100 10.43200  1.000 37.47763  ? 150 CYS   H C   1 
ATOM   1096 O  O   . CYS   A 1 150 ? 9.18500   12.64000 9.82300   1.000 34.62675  ? 150 CYS   H O   1 
ATOM   1097 C  CB  . CYS   A 1 150 ? 11.20000  10.32400 9.78500   1.000 35.69354  ? 150 CYS   H CB  1 
ATOM   1098 S  SG  . CYS   A 1 150 ? 12.42200  9.05600  10.22600  1.000 57.56469  ? 150 CYS   H SG  1 
ATOM   1099 N  N   . LEU   A 1 151 ? 11.08900  13.54200 10.64200  1.000 33.29289  ? 151 LEU   H N   1 
ATOM   1100 C  CA  . LEU   A 1 151 ? 10.86500  14.87700 10.10700  1.000 38.19181  ? 151 LEU   H CA  1 
ATOM   1101 C  C   . LEU   A 1 151 ? 11.68000  15.03300 8.83000   1.000 40.81640  ? 151 LEU   H C   1 
ATOM   1102 O  O   . LEU   A 1 151 ? 12.91300  14.97800 8.86500   1.000 42.27490  ? 151 LEU   H O   1 
ATOM   1103 C  CB  . LEU   A 1 151 ? 11.25300  15.94800 11.12500  1.000 38.23751  ? 151 LEU   H CB  1 
ATOM   1104 C  CG  . LEU   A 1 151 ? 11.16100  17.40600 10.65900  1.000 38.38816  ? 151 LEU   H CG  1 
ATOM   1105 C  CD1 . LEU   A 1 151 ? 9.71400   17.84000 10.45100  1.000 38.69708  ? 151 LEU   H CD1 1 
ATOM   1106 C  CD2 . LEU   A 1 151 ? 11.86200  18.33900 11.63500  1.000 30.57543  ? 151 LEU   H CD2 1 
ATOM   1107 N  N   . VAL   A 1 152 ? 10.99100  15.21200 7.71100   1.000 40.86842  ? 152 VAL   H N   1 
ATOM   1108 C  CA  . VAL   A 1 152 ? 11.62500  15.35900 6.40800   1.000 42.15407  ? 152 VAL   H CA  1 
ATOM   1109 C  C   . VAL   A 1 152 ? 11.60700  16.84800 6.08500   1.000 41.95957  ? 152 VAL   H C   1 
ATOM   1110 O  O   . VAL   A 1 152 ? 10.56700  17.40600 5.72900   1.000 43.43618  ? 152 VAL   H O   1 
ATOM   1111 C  CB  . VAL   A 1 152 ? 10.91200  14.52600 5.34200   1.000 43.25268  ? 152 VAL   H CB  1 
ATOM   1112 C  CG1 . VAL   A 1 152 ? 11.62900  14.63400 4.02100   1.000 37.43734  ? 152 VAL   H CG1 1 
ATOM   1113 C  CG2 . VAL   A 1 152 ? 10.82600  13.07000 5.78600   1.000 38.98147  ? 152 VAL   H CG2 1 
ATOM   1114 N  N   . LYS   A 1 153 ? 12.76300  17.49500 6.20900   1.000 43.09234  ? 153 LYS   H N   1 
ATOM   1115 C  CA  . LYS   A 1 153 ? 12.85500  18.94900 6.22300   1.000 41.49855  ? 153 LYS   H CA  1 
ATOM   1116 C  C   . LYS   A 1 153 ? 13.60000  19.46400 4.99700   1.000 45.45328  ? 153 LYS   H C   1 
ATOM   1117 O  O   . LYS   A 1 153 ? 14.66400  18.94300 4.64600   1.000 41.94241  ? 153 LYS   H O   1 
ATOM   1118 C  CB  . LYS   A 1 153 ? 13.55400  19.42600 7.49800   1.000 38.26508  ? 153 LYS   H CB  1 
ATOM   1119 C  CG  . LYS   A 1 153 ? 13.61900  20.93500 7.64600   1.000 47.39140  ? 153 LYS   H CG  1 
ATOM   1120 C  CD  . LYS   A 1 153 ? 12.53300  21.45500 8.57000   1.000 39.13915  ? 153 LYS   H CD  1 
ATOM   1121 C  CE  . LYS   A 1 153 ? 13.01700  22.67200 9.33700   1.000 50.35625  ? 153 LYS   H CE  1 
ATOM   1122 N  NZ  . LYS   A 1 153 ? 13.79000  23.60500 8.47100   1.000 51.05340  ? 153 LYS   H NZ  1 
ATOM   1123 N  N   . ASP   A 1 154 ? 13.03100  20.48800 4.35700   1.000 47.51493  ? 154 ASP   H N   1 
ATOM   1124 C  CA  . ASP   A 1 154 ? 13.67700  21.24700 3.28900   1.000 51.34507  ? 154 ASP   H CA  1 
ATOM   1125 C  C   . ASP   A 1 154 ? 14.05100  20.38700 2.08800   1.000 49.37428  ? 154 ASP   H C   1 
ATOM   1126 O  O   . ASP   A 1 154 ? 15.14400  19.81300 2.04000   1.000 52.91435  ? 154 ASP   H O   1 
ATOM   1127 C  CB  . ASP   A 1 154 ? 14.91700  21.96500 3.82600   1.000 46.14675  ? 154 ASP   H CB  1 
ATOM   1128 C  CG  . ASP   A 1 154 ? 14.58100  22.96900 4.90900   1.000 50.35873  ? 154 ASP   H CG  1 
ATOM   1129 O  OD1 . ASP   A 1 154 ? 13.60000  23.72300 4.73600   1.000 58.12894  ? 154 ASP   H OD1 1 
ATOM   1130 O  OD2 . ASP   A 1 154 ? 15.29600  23.00500 5.93100   1.000 51.24601  ? 154 ASP   H OD2 1 
ATOM   1131 N  N   . TYR   A 1 155 ? 13.15500  20.31100 1.10700   1.000 44.64412  ? 155 TYR   H N   1 
ATOM   1132 C  CA  . TYR   A 1 155 ? 13.42200  19.59200 -0.12900  1.000 36.04285  ? 155 TYR   H CA  1 
ATOM   1133 C  C   . TYR   A 1 155 ? 12.60700  20.21800 -1.25000  1.000 36.63543  ? 155 TYR   H C   1 
ATOM   1134 O  O   . TYR   A 1 155 ? 11.54700  20.80300 -1.01400  1.000 40.95971  ? 155 TYR   H O   1 
ATOM   1135 C  CB  . TYR   A 1 155 ? 13.09600  18.09900 -0.00000  1.000 39.10316  ? 155 TYR   H CB  1 
ATOM   1136 C  CG  . TYR   A 1 155 ? 11.62300  17.79600 0.16600   1.000 40.14424  ? 155 TYR   H CG  1 
ATOM   1137 C  CD1 . TYR   A 1 155 ? 10.78900  17.66400 -0.93900  1.000 38.30835  ? 155 TYR   H CD1 1 
ATOM   1138 C  CD2 . TYR   A 1 155 ? 11.06600  17.63700 1.42800   1.000 39.18265  ? 155 TYR   H CD2 1 
ATOM   1139 C  CE1 . TYR   A 1 155 ? 9.44500   17.39300 -0.79300  1.000 38.78256  ? 155 TYR   H CE1 1 
ATOM   1140 C  CE2 . TYR   A 1 155 ? 9.72200   17.36000 1.58500   1.000 34.30107  ? 155 TYR   H CE2 1 
ATOM   1141 C  CZ  . TYR   A 1 155 ? 8.91900   17.23600 0.47000   1.000 36.76005  ? 155 TYR   H CZ  1 
ATOM   1142 O  OH  . TYR   A 1 155 ? 7.58100   16.96100 0.61400   1.000 30.38335  ? 155 TYR   H OH  1 
ATOM   1143 N  N   . PHE   A 1 156 ? 13.10700  20.07000 -2.47800  1.000 36.68885  ? 156 PHE   H N   1 
ATOM   1144 C  CA  . PHE   A 1 156 ? 12.44500  20.61300 -3.65400  1.000 37.12653  ? 156 PHE   H CA  1 
ATOM   1145 C  C   . PHE   A 1 156 ? 12.92300  19.82700 -4.85900  1.000 38.98518  ? 156 PHE   H C   1 
ATOM   1146 O  O   . PHE   A 1 156 ? 14.10900  19.47800 -4.91600  1.000 42.92633  ? 156 PHE   H O   1 
ATOM   1147 C  CB  . PHE   A 1 156 ? 12.75700  22.10500 -3.82600  1.000 35.97241  ? 156 PHE   H CB  1 
ATOM   1148 C  CG  . PHE   A 1 156 ? 11.93600  22.78300 -4.88600  1.000 35.56154  ? 156 PHE   H CG  1 
ATOM   1149 C  CD1 . PHE   A 1 156 ? 10.70300  23.33200 -4.57800  1.000 35.10502  ? 156 PHE   H CD1 1 
ATOM   1150 C  CD2 . PHE   A 1 156 ? 12.40000  22.87600 -6.18700  1.000 40.38409  ? 156 PHE   H CD2 1 
ATOM   1151 C  CE1 . PHE   A 1 156 ? 9.94600   23.95800 -5.55000  1.000 32.87978  ? 156 PHE   H CE1 1 
ATOM   1152 C  CE2 . PHE   A 1 156 ? 11.64800  23.50100 -7.16300  1.000 37.85455  ? 156 PHE   H CE2 1 
ATOM   1153 C  CZ  . PHE   A 1 156 ? 10.41900  24.04200 -6.84300  1.000 31.28293  ? 156 PHE   H CZ  1 
ATOM   1154 N  N   . PRO   A 1 157 ? 12.04500  19.50200 -5.82000  1.000 37.12492  ? 157 PRO   H N   1 
ATOM   1155 C  CA  . PRO   A 1 157 ? 10.60600  19.76200 -5.76700  1.000 39.15387  ? 157 PRO   H CA  1 
ATOM   1156 C  C   . PRO   A 1 157 ? 9.85000   18.61700 -5.10500  1.000 42.53825  ? 157 PRO   H C   1 
ATOM   1157 O  O   . PRO   A 1 157 ? 10.46900  17.73100 -4.51300  1.000 39.75750  ? 157 PRO   H O   1 
ATOM   1158 C  CB  . PRO   A 1 157 ? 10.23200  19.87700 -7.24300  1.000 38.42277  ? 157 PRO   H CB  1 
ATOM   1159 C  CG  . PRO   A 1 157 ? 11.14900  18.89400 -7.90600  1.000 33.38856  ? 157 PRO   H CG  1 
ATOM   1160 C  CD  . PRO   A 1 157 ? 12.44400  18.91900 -7.11400  1.000 39.60152  ? 157 PRO   H CD  1 
ATOM   1161 N  N   . GLU   A 1 158 ? 8.52200   18.64400 -5.19900  1.000 40.93056  ? 158 GLU   H N   1 
ATOM   1162 C  CA  . GLU   A 1 158 ? 7.73400   17.48200 -4.83600  1.000 35.88252  ? 158 GLU   H CA  1 
ATOM   1163 C  C   . GLU   A 1 158 ? 8.06900   16.33600 -5.78800  1.000 38.14286  ? 158 GLU   H C   1 
ATOM   1164 O  O   . GLU   A 1 158 ? 8.54400   16.56600 -6.90300  1.000 41.47773  ? 158 GLU   H O   1 
ATOM   1165 C  CB  . GLU   A 1 158 ? 6.24200   17.81200 -4.90000  1.000 40.23098  ? 158 GLU   H CB  1 
ATOM   1166 C  CG  . GLU   A 1 158 ? 5.76000   18.76900 -3.82100  1.000 34.77720  ? 158 GLU   H CG  1 
ATOM   1167 C  CD  . GLU   A 1 158 ? 5.31100   18.05500 -2.56100  1.000 48.03275  ? 158 GLU   H CD  1 
ATOM   1168 O  OE1 . GLU   A 1 158 ? 4.14200   18.23700 -2.16100  1.000 47.17300  ? 158 GLU   H OE1 1 
ATOM   1169 O  OE2 . GLU   A 1 158 ? 6.12500   17.31400 -1.96900  1.000 49.97513  ? 158 GLU   H OE2 1 
ATOM   1170 N  N   . PRO   A 1 159 ? 7.83300   15.08000 -5.37400  1.000 40.31997  ? 159 PRO   H N   1 
ATOM   1171 C  CA  . PRO   A 1 159 ? 7.35100   14.59800 -4.07900  1.000 38.77131  ? 159 PRO   H CA  1 
ATOM   1172 C  C   . PRO   A 1 159 ? 8.38900   13.78000 -3.31500  1.000 40.19016  ? 159 PRO   H C   1 
ATOM   1173 O  O   . PRO   A 1 159 ? 9.44200   13.45900 -3.86400  1.000 42.68596  ? 159 PRO   H O   1 
ATOM   1174 C  CB  . PRO   A 1 159 ? 6.17500   13.70900 -4.48000  1.000 32.97118  ? 159 PRO   H CB  1 
ATOM   1175 C  CG  . PRO   A 1 159 ? 6.56200   13.18500 -5.87800  1.000 30.55424  ? 159 PRO   H CG  1 
ATOM   1176 C  CD  . PRO   A 1 159 ? 7.72500   14.02000 -6.38800  1.000 31.76491  ? 159 PRO   H CD  1 
ATOM   1177 N  N   . VAL   A 1 160 ? 8.09900   13.44400 -2.06100  1.000 40.26896  ? 160 VAL   H N   1 
ATOM   1178 C  CA  . VAL   A 1 160 ? 8.83400   12.40800 -1.34700  1.000 43.46870  ? 160 VAL   H CA  1 
ATOM   1179 C  C   . VAL   A 1 160 ? 7.83500   11.37500 -0.85000  1.000 46.61701  ? 160 VAL   H C   1 
ATOM   1180 O  O   . VAL   A 1 160 ? 6.69900   11.71100 -0.49500  1.000 49.10834  ? 160 VAL   H O   1 
ATOM   1181 C  CB  . VAL   A 1 160 ? 9.68100   12.95400 -0.17400  1.000 39.58295  ? 160 VAL   H CB  1 
ATOM   1182 C  CG1 . VAL   A 1 160 ? 10.45500  14.18000 -0.59300  1.000 39.98591  ? 160 VAL   H CG1 1 
ATOM   1183 C  CG2 . VAL   A 1 160 ? 8.82600   13.23400 1.05300   1.000 37.96724  ? 160 VAL   H CG2 1 
ATOM   1184 N  N   . THR   A 1 161 ? 8.25200   10.11700 -0.85600  1.000 42.60693  ? 161 THR   H N   1 
ATOM   1185 C  CA  . THR   A 1 161 ? 7.50100   9.04200  -0.23500  1.000 36.74951  ? 161 THR   H CA  1 
ATOM   1186 C  C   . THR   A 1 161 ? 8.17400   8.66200  1.07600   1.000 40.80621  ? 161 THR   H C   1 
ATOM   1187 O  O   . THR   A 1 161 ? 9.39400   8.77000  1.22200   1.000 43.30739  ? 161 THR   H O   1 
ATOM   1188 C  CB  . THR   A 1 161 ? 7.41700   7.81800  -1.15000  1.000 45.05618  ? 161 THR   H CB  1 
ATOM   1189 O  OG1 . THR   A 1 161 ? 8.73400   7.30600  -1.39200  1.000 53.38732  ? 161 THR   H OG1 1 
ATOM   1190 C  CG2 . THR   A 1 161 ? 6.77100   8.18800  -2.47900  1.000 41.67898  ? 161 THR   H CG2 1 
ATOM   1191 N  N   . VAL   A 1 162 ? 7.36500   8.23100  2.03800   1.000 43.66819  ? 162 VAL   H N   1 
ATOM   1192 C  CA  . VAL   A 1 162 ? 7.86300   7.75300  3.31900   1.000 42.49017  ? 162 VAL   H CA  1 
ATOM   1193 C  C   . VAL   A 1 162 ? 7.19200   6.42300  3.62100   1.000 38.27256  ? 162 VAL   H C   1 
ATOM   1194 O  O   . VAL   A 1 162 ? 5.99200   6.25200  3.37600   1.000 41.30915  ? 162 VAL   H O   1 
ATOM   1195 C  CB  . VAL   A 1 162 ? 7.60600   8.76100  4.46000   1.000 43.09447  ? 162 VAL   H CB  1 
ATOM   1196 C  CG1 . VAL   A 1 162 ? 8.16100   8.22500  5.77400   1.000 32.86518  ? 162 VAL   H CG1 1 
ATOM   1197 C  CG2 . VAL   A 1 162 ? 8.22300   10.11200 4.13600   1.000 38.69372  ? 162 VAL   H CG2 1 
ATOM   1198 N  N   . SER   A 1 163 ? 7.97300   5.47600  4.13400   1.000 42.78179  ? 163 SER   H N   1 
ATOM   1199 C  CA  . SER   A 1 163 ? 7.45000   4.19900  4.59300   1.000 39.71316  ? 163 SER   H CA  1 
ATOM   1200 C  C   . SER   A 1 163 ? 8.23700   3.77800  5.82400   1.000 38.01074  ? 163 SER   H C   1 
ATOM   1201 O  O   . SER   A 1 163 ? 9.28300   4.34900  6.14400   1.000 41.48543  ? 163 SER   H O   1 
ATOM   1202 C  CB  . SER   A 1 163 ? 7.52000   3.13000  3.49600   1.000 38.42470  ? 163 SER   H CB  1 
ATOM   1203 O  OG  . SER   A 1 163 ? 8.83200   2.61500  3.36300   1.000 46.48416  ? 163 SER   H OG  1 
ATOM   1204 N  N   . TRP   A 1 164 ? 7.72000   2.77100  6.52100   1.000 40.99757  ? 164 TRP   H N   1 
ATOM   1205 C  CA  . TRP   A 1 164 ? 8.30100   2.30200  7.77000   1.000 44.27029  ? 164 TRP   H CA  1 
ATOM   1206 C  C   . TRP   A 1 164 ? 8.61400   0.81900  7.66000   1.000 44.65703  ? 164 TRP   H C   1 
ATOM   1207 O  O   . TRP   A 1 164 ? 7.75500   0.02800  7.25400   1.000 44.66955  ? 164 TRP   H O   1 
ATOM   1208 C  CB  . TRP   A 1 164 ? 7.35800   2.57000  8.94300   1.000 43.41508  ? 164 TRP   H CB  1 
ATOM   1209 C  CG  . TRP   A 1 164 ? 7.22200   4.02600  9.24900   1.000 44.85879  ? 164 TRP   H CG  1 
ATOM   1210 C  CD1 . TRP   A 1 164 ? 6.32400   4.90000  8.70900   1.000 43.76310  ? 164 TRP   H CD1 1 
ATOM   1211 C  CD2 . TRP   A 1 164 ? 8.02700   4.78600  10.15500  1.000 44.43277  ? 164 TRP   H CD2 1 
ATOM   1212 N  NE1 . TRP   A 1 164 ? 6.51500   6.15700  9.22900   1.000 41.52016  ? 164 TRP   H NE1 1 
ATOM   1213 C  CE2 . TRP   A 1 164 ? 7.55600   6.11400  10.11900  1.000 45.30826  ? 164 TRP   H CE2 1 
ATOM   1214 C  CE3 . TRP   A 1 164 ? 9.09800   4.47300  10.99600  1.000 45.44379  ? 164 TRP   H CE3 1 
ATOM   1215 C  CZ2 . TRP   A 1 164 ? 8.11900   7.12500  10.89300  1.000 37.26820  ? 164 TRP   H CZ2 1 
ATOM   1216 C  CZ3 . TRP   A 1 164 ? 9.65500   5.47600  11.76200  1.000 46.78757  ? 164 TRP   H CZ3 1 
ATOM   1217 C  CH2 . TRP   A 1 164 ? 9.16500   6.78600  11.70600  1.000 41.70226  ? 164 TRP   H CH2 1 
ATOM   1218 N  N   . ASN   A 1 165 ? 9.84300   0.45600  8.02900   1.000 46.37893  ? 165 ASN   H N   1 
ATOM   1219 C  CA  . ASN   A 1 165 ? 10.33400  -0.91500 7.92600   1.000 51.22018  ? 165 ASN   H CA  1 
ATOM   1220 C  C   . ASN   A 1 165 ? 10.12100  -1.44500 6.50700   1.000 52.26004  ? 165 ASN   H C   1 
ATOM   1221 O  O   . ASN   A 1 165 ? 9.69800   -2.58300 6.29900   1.000 44.51549  ? 165 ASN   H O   1 
ATOM   1222 C  CB  . ASN   A 1 165 ? 9.67600   -1.81300 8.97800   1.000 46.72993  ? 165 ASN   H CB  1 
ATOM   1223 C  CG  . ASN   A 1 165 ? 10.00900  -1.38600 10.39000  1.000 48.78978  ? 165 ASN   H CG  1 
ATOM   1224 O  OD1 . ASN   A 1 165 ? 11.04700  -0.76700 10.63100  1.000 46.10921  ? 165 ASN   H OD1 1 
ATOM   1225 N  ND2 . ASN   A 1 165 ? 9.12600   -1.70200 11.33200  1.000 50.48426  ? 165 ASN   H ND2 1 
ATOM   1226 N  N   . SER   A 1 166 ? 10.42300  -0.58400 5.53100   1.000 48.49813  ? 166 SER   H N   1 
ATOM   1227 C  CA  . SER   A 1 166 ? 10.21800  -0.81800 4.09600   1.000 50.99137  ? 166 SER   H CA  1 
ATOM   1228 C  C   . SER   A 1 166 ? 8.94400   -1.61400 3.81700   1.000 44.74769  ? 166 SER   H C   1 
ATOM   1229 O  O   . SER   A 1 166 ? 8.96900   -2.74600 3.33500   1.000 45.65564  ? 166 SER   H O   1 
ATOM   1230 C  CB  . SER   A 1 166 ? 11.43800  -1.49900 3.47700   1.000 49.72837  ? 166 SER   H CB  1 
ATOM   1231 O  OG  . SER   A 1 166 ? 12.07400  -2.38900 4.38300   1.000 48.37183  ? 166 SER   H OG  1 
ATOM   1232 N  N   . GLY   A 1 167 ? 7.81700   -0.98900 4.14700   1.000 47.80519  ? 167 GLY   H N   1 
ATOM   1233 C  CA  . GLY   A 1 167 ? 6.51100   -1.50900 3.81400   1.000 41.50819  ? 167 GLY   H CA  1 
ATOM   1234 C  C   . GLY   A 1 167 ? 5.86400   -2.41000 4.84700   1.000 46.54049  ? 167 GLY   H C   1 
ATOM   1235 O  O   . GLY   A 1 167 ? 4.65500   -2.65600 4.74900   1.000 44.39906  ? 167 GLY   H O   1 
ATOM   1236 N  N   . ALA   A 1 168 ? 6.61600   -2.91500 5.83100   1.000 46.84445  ? 168 ALA   H N   1 
ATOM   1237 C  CA  . ALA   A 1 168 ? 6.04100   -3.88700 6.76100   1.000 43.34462  ? 168 ALA   H CA  1 
ATOM   1238 C  C   . ALA   A 1 168 ? 5.11900   -3.21700 7.77700   1.000 47.81702  ? 168 ALA   H C   1 
ATOM   1239 O  O   . ALA   A 1 168 ? 4.03700   -3.73700 8.07700   1.000 47.64850  ? 168 ALA   H O   1 
ATOM   1240 C  CB  . ALA   A 1 168 ? 7.15000   -4.66600 7.47000   1.000 52.87605  ? 168 ALA   H CB  1 
ATOM   1241 N  N   . LEU   A 1 169 ? 5.53000   -2.07300 8.32200   1.000 49.35532  ? 169 LEU   H N   1 
ATOM   1242 C  CA  . LEU   A 1 169 ? 4.72100   -1.35000 9.29700   1.000 49.51916  ? 169 LEU   H CA  1 
ATOM   1243 C  C   . LEU   A 1 169 ? 3.74100   -0.43800 8.56900   1.000 47.36263  ? 169 LEU   H C   1 
ATOM   1244 O  O   . LEU   A 1 169 ? 4.14800   0.41300  7.77100   1.000 49.76514  ? 169 LEU   H O   1 
ATOM   1245 C  CB  . LEU   A 1 169 ? 5.61000   -0.54300 10.24200  1.000 51.28728  ? 169 LEU   H CB  1 
ATOM   1246 C  CG  . LEU   A 1 169 ? 4.89700   0.07000  11.44900  1.000 46.49070  ? 169 LEU   H CG  1 
ATOM   1247 C  CD1 . LEU   A 1 169 ? 5.16300   -0.75300 12.69600  1.000 44.37145  ? 169 LEU   H CD1 1 
ATOM   1248 C  CD2 . LEU   A 1 169 ? 5.33400   1.50700  11.65100  1.000 48.26798  ? 169 LEU   H CD2 1 
ATOM   1249 N  N   . THR   A 1 170 ? 2.45200   -0.61200 8.84300   1.000 45.53402  ? 170 THR   H N   1 
ATOM   1250 C  CA  . THR   A 1 170 ? 1.43500   0.17800  8.16300   1.000 42.65934  ? 170 THR   H CA  1 
ATOM   1251 C  C   . THR   A 1 170 ? 0.43100   0.73500  9.15800   1.000 40.36548  ? 170 THR   H C   1 
ATOM   1252 O  O   . THR   A 1 170 ? -0.08200  1.84500  8.98500   1.000 47.36186  ? 170 THR   H O   1 
ATOM   1253 C  CB  . THR   A 1 170 ? 0.71400   -0.66800 7.11100   1.000 46.68740  ? 170 THR   H CB  1 
ATOM   1254 O  OG1 . THR   A 1 170 ? 0.57700   -2.01400 7.58600   1.000 50.54833  ? 170 THR   H OG1 1 
ATOM   1255 C  CG2 . THR   A 1 170 ? 1.48100   -0.66500 5.80400   1.000 38.18567  ? 170 THR   H CG2 1 
ATOM   1256 N  N   . SER   A 1 171 ? 0.14400   -0.02900 10.20500  1.000 40.36746  ? 171 SER   H N   1 
ATOM   1257 C  CA  . SER   A 1 171 ? -0.86700  0.37400  11.16900  1.000 45.02054  ? 171 SER   H CA  1 
ATOM   1258 C  C   . SER   A 1 171 ? -0.33400  1.46700  12.08400  1.000 46.41398  ? 171 SER   H C   1 
ATOM   1259 O  O   . SER   A 1 171 ? 0.82900   1.44200  12.49900  1.000 45.16696  ? 171 SER   H O   1 
ATOM   1260 C  CB  . SER   A 1 171 ? -1.33100  -0.81500 12.00600  1.000 38.51134  ? 171 SER   H CB  1 
ATOM   1261 O  OG  . SER   A 1 171 ? -1.66800  -0.38500 13.31500  1.000 50.88077  ? 171 SER   H OG  1 
ATOM   1262 N  N   . GLY   A 1 172 ? -1.20200  2.42800  12.40500  1.000 44.67537  ? 172 GLY   H N   1 
ATOM   1263 C  CA  . GLY   A 1 172 ? -0.83600  3.54600  13.24500  1.000 47.25101  ? 172 GLY   H CA  1 
ATOM   1264 C  C   . GLY   A 1 172 ? -0.05800  4.64000  12.55100  1.000 46.17016  ? 172 GLY   H C   1 
ATOM   1265 O  O   . GLY   A 1 172 ? 0.13100   5.71300  13.14100  1.000 42.98997  ? 172 GLY   H O   1 
ATOM   1266 N  N   . VAL   A 1 173 ? 0.39700   4.41300  11.32000  1.000 43.26923  ? 173 VAL   H N   1 
ATOM   1267 C  CA  . VAL   A 1 173 ? 1.15500   5.42600  10.60000  1.000 43.52594  ? 173 VAL   H CA  1 
ATOM   1268 C  C   . VAL   A 1 173 ? 0.21000   6.51500  10.11500  1.000 40.04732  ? 173 VAL   H C   1 
ATOM   1269 O  O   . VAL   A 1 173 ? -0.86800  6.23100  9.57500   1.000 49.04729  ? 173 VAL   H O   1 
ATOM   1270 C  CB  . VAL   A 1 173 ? 1.92100   4.79600  9.42800   1.000 44.60269  ? 173 VAL   H CB  1 
ATOM   1271 C  CG1 . VAL   A 1 173 ? 2.79500   5.83900  8.74300   1.000 45.25568  ? 173 VAL   H CG1 1 
ATOM   1272 C  CG2 . VAL   A 1 173 ? 2.76100   3.62400  9.90900   1.000 43.46400  ? 173 VAL   H CG2 1 
ATOM   1273 N  N   . HIS   A 1 174 ? 0.60700   7.76900  10.31900  1.000 41.23056  ? 174 HIS   H N   1 
ATOM   1274 C  CA  . HIS   A 1 174 ? -0.09200  8.92700  9.77100   1.000 39.87651  ? 174 HIS   H CA  1 
ATOM   1275 C  C   . HIS   A 1 174 ? 0.94800   9.82100  9.10900   1.000 33.53873  ? 174 HIS   H C   1 
ATOM   1276 O  O   . HIS   A 1 174 ? 1.70900   10.51300 9.79400   1.000 32.18317  ? 174 HIS   H O   1 
ATOM   1277 C  CB  . HIS   A 1 174 ? -0.87400  9.67700  10.85200  1.000 33.60358  ? 174 HIS   H CB  1 
ATOM   1278 C  CG  . HIS   A 1 174 ? -1.76800  8.79400  11.66800  1.000 39.66642  ? 174 HIS   H CG  1 
ATOM   1279 N  ND1 . HIS   A 1 174 ? -3.01800  8.40200  11.23900  1.000 43.37453  ? 174 HIS   H ND1 1 
ATOM   1280 C  CD2 . HIS   A 1 174 ? -1.59300  8.22500  12.88500  1.000 53.21979  ? 174 HIS   H CD2 1 
ATOM   1281 C  CE1 . HIS   A 1 174 ? -3.57100  7.62400  12.15400  1.000 53.66981  ? 174 HIS   H CE1 1 
ATOM   1282 N  NE2 . HIS   A 1 174 ? -2.73000  7.50600  13.16500  1.000 41.55136  ? 174 HIS   H NE2 1 
ATOM   1283 N  N   . THR   A 1 175 ? 0.98800   9.79300  7.78100   1.000 35.91654  ? 175 THR   H N   1 
ATOM   1284 C  CA  . THR   A 1 175 ? 1.96100   10.53900 6.99600   1.000 33.70980  ? 175 THR   H CA  1 
ATOM   1285 C  C   . THR   A 1 175 ? 1.29000   11.77500 6.41400   1.000 27.84183  ? 175 THR   H C   1 
ATOM   1286 O  O   . THR   A 1 175 ? 0.21500   11.67900 5.81300   1.000 31.36109  ? 175 THR   H O   1 
ATOM   1287 C  CB  . THR   A 1 175 ? 2.54200   9.66100  5.88800   1.000 30.43140  ? 175 THR   H CB  1 
ATOM   1288 O  OG1 . THR   A 1 175 ? 3.35700   8.63900  6.47500   1.000 33.80648  ? 175 THR   H OG1 1 
ATOM   1289 C  CG2 . THR   A 1 175 ? 3.38800   10.48900 4.94200   1.000 25.39679  ? 175 THR   H CG2 1 
ATOM   1290 N  N   . PHE   A 1 176 ? 1.93400   12.92900 6.57700   1.000 25.23797  ? 176 PHE   H N   1 
ATOM   1291 C  CA  . PHE   A 1 176 ? 1.20300   14.16400 6.35100   1.000 28.12295  ? 176 PHE   H CA  1 
ATOM   1292 C  C   . PHE   A 1 176 ? 1.51100   14.76400 4.98500   1.000 32.62097  ? 176 PHE   H C   1 
ATOM   1293 O  O   . PHE   A 1 176 ? 2.58700   14.53700 4.42200   1.000 34.88969  ? 176 PHE   H O   1 
ATOM   1294 C  CB  . PHE   A 1 176 ? 1.54500   15.18600 7.43600   1.000 28.85753  ? 176 PHE   H CB  1 
ATOM   1295 C  CG  . PHE   A 1 176 ? 1.06100   14.80000 8.80000   1.000 32.16371  ? 176 PHE   H CG  1 
ATOM   1296 C  CD1 . PHE   A 1 176 ? -0.20800  15.15100 9.22200   1.000 31.49203  ? 176 PHE   H CD1 1 
ATOM   1297 C  CD2 . PHE   A 1 176 ? 1.87000   14.07000 9.65300   1.000 30.75465  ? 176 PHE   H CD2 1 
ATOM   1298 C  CE1 . PHE   A 1 176 ? -0.65600  14.79400 10.47500  1.000 33.49560  ? 176 PHE   H CE1 1 
ATOM   1299 C  CE2 . PHE   A 1 176 ? 1.42700   13.70900 10.90600  1.000 31.52527  ? 176 PHE   H CE2 1 
ATOM   1300 C  CZ  . PHE   A 1 176 ? 0.16200   14.07200 11.31900  1.000 34.61518  ? 176 PHE   H CZ  1 
ATOM   1301 N  N   . PRO   A 1 177 ? 0.56300   15.52700 4.43900   1.000 35.01623  ? 177 PRO   H N   1 
ATOM   1302 C  CA  . PRO   A 1 177 ? 0.84500   16.30100 3.22500   1.000 31.91728  ? 177 PRO   H CA  1 
ATOM   1303 C  C   . PRO   A 1 177 ? 1.99000   17.27500 3.45200   1.000 35.24836  ? 177 PRO   H C   1 
ATOM   1304 O  O   . PRO   A 1 177 ? 2.14600   17.84000 4.53700   1.000 33.58853  ? 177 PRO   H O   1 
ATOM   1305 C  CB  . PRO   A 1 177 ? -0.47300  17.03700 2.96100   1.000 31.03842  ? 177 PRO   H CB  1 
ATOM   1306 C  CG  . PRO   A 1 177 ? -1.51100  16.18300 3.60400   1.000 38.64965  ? 177 PRO   H CG  1 
ATOM   1307 C  CD  . PRO   A 1 177 ? -0.86000  15.59000 4.81900   1.000 35.87040  ? 177 PRO   H CD  1 
ATOM   1308 N  N   . ALA   A 1 178 ? 2.79700   17.46500 2.41200   1.000 40.74620  ? 178 ALA   H N   1 
ATOM   1309 C  CA  . ALA   A 1 178 ? 3.92200   18.38300 2.50400   1.000 35.00777  ? 178 ALA   H CA  1 
ATOM   1310 C  C   . ALA   A 1 178 ? 3.42900   19.81200 2.69200   1.000 37.78388  ? 178 ALA   H C   1 
ATOM   1311 O  O   . ALA   A 1 178 ? 2.31100   20.16500 2.30600   1.000 38.56667  ? 178 ALA   H O   1 
ATOM   1312 C  CB  . ALA   A 1 178 ? 4.79400   18.28500 1.25400   1.000 38.14533  ? 178 ALA   H CB  1 
ATOM   1313 N  N   . VAL   A 1 179 ? 4.27500   20.63800 3.30000   1.000 41.44166  ? 179 VAL   H N   1 
ATOM   1314 C  CA  . VAL   A 1 179 ? 3.95800   22.03300 3.57500   1.000 36.67670  ? 179 VAL   H CA  1 
ATOM   1315 C  C   . VAL   A 1 179 ? 5.02900   22.90400 2.93600   1.000 38.04287  ? 179 VAL   H C   1 
ATOM   1316 O  O   . VAL   A 1 179 ? 6.21600   22.56000 2.95300   1.000 41.16663  ? 179 VAL   H O   1 
ATOM   1317 C  CB  . VAL   A 1 179 ? 3.85600   22.30400 5.09000   1.000 31.83131  ? 179 VAL   H CB  1 
ATOM   1318 C  CG1 . VAL   A 1 179 ? 3.48400   23.75000 5.34700   1.000 42.68594  ? 179 VAL   H CG1 1 
ATOM   1319 C  CG2 . VAL   A 1 179 ? 2.83800   21.37200 5.72700   1.000 39.70289  ? 179 VAL   H CG2 1 
ATOM   1320 N  N   . LEU   A 1 180 ? 4.60500   24.02700 2.36200   1.000 38.98924  ? 180 LEU   H N   1 
ATOM   1321 C  CA  . LEU   A 1 180 ? 5.51500   24.95800 1.70400   1.000 37.74494  ? 180 LEU   H CA  1 
ATOM   1322 C  C   . LEU   A 1 180 ? 6.00900   25.97100 2.73000   1.000 40.98592  ? 180 LEU   H C   1 
ATOM   1323 O  O   . LEU   A 1 180 ? 5.24200   26.82100 3.19500   1.000 41.79777  ? 180 LEU   H O   1 
ATOM   1324 C  CB  . LEU   A 1 180 ? 4.82400   25.65600 0.53500   1.000 42.18605  ? 180 LEU   H CB  1 
ATOM   1325 C  CG  . LEU   A 1 180 ? 5.74100   26.40100 -0.43800  1.000 43.36126  ? 180 LEU   H CG  1 
ATOM   1326 C  CD1 . LEU   A 1 180 ? 6.92500   25.53300 -0.84600  1.000 44.87735  ? 180 LEU   H CD1 1 
ATOM   1327 C  CD2 . LEU   A 1 180 ? 4.96400   26.86100 -1.66000  1.000 40.11465  ? 180 LEU   H CD2 1 
ATOM   1328 N  N   . GLN   A 1 181 ? 7.28600   25.87700 3.08600   1.000 41.08533  ? 181 GLN   H N   1 
ATOM   1329 C  CA  . GLN   A 1 181 ? 7.88600   26.87100 3.95900   1.000 47.31559  ? 181 GLN   H CA  1 
ATOM   1330 C  C   . GLN   A 1 181 ? 8.13400   28.16500 3.19100   1.000 47.38725  ? 181 GLN   H C   1 
ATOM   1331 O  O   . GLN   A 1 181 ? 8.14200   28.19600 1.95700   1.000 46.46281  ? 181 GLN   H O   1 
ATOM   1332 C  CB  . GLN   A 1 181 ? 9.20100   26.35200 4.54000   1.000 48.07095  ? 181 GLN   H CB  1 
ATOM   1333 C  CG  . GLN   A 1 181 ? 9.04100   25.27500 5.59800   1.000 42.47109  ? 181 GLN   H CG  1 
ATOM   1334 C  CD  . GLN   A 1 181 ? 10.11900  24.21200 5.51000   1.000 52.32039  ? 181 GLN   H CD  1 
ATOM   1335 O  OE1 . GLN   A 1 181 ? 10.62300  23.73700 6.52700   1.000 58.17512  ? 181 GLN   H OE1 1 
ATOM   1336 N  NE2 . GLN   A 1 181 ? 10.47600  23.83100 4.28800   1.000 49.21196  ? 181 GLN   H NE2 1 
ATOM   1337 N  N   . SER   A 1 182 ? 8.34200   29.25100 3.94000   1.000 46.69454  ? 182 SER   H N   1 
ATOM   1338 C  CA  . SER   A 1 182 ? 8.77000   30.49700 3.31400   1.000 41.50829  ? 182 SER   H CA  1 
ATOM   1339 C  C   . SER   A 1 182 ? 10.13500  30.35200 2.65500   1.000 42.59424  ? 182 SER   H C   1 
ATOM   1340 O  O   . SER   A 1 182 ? 10.51100  31.19400 1.83300   1.000 48.56002  ? 182 SER   H O   1 
ATOM   1341 C  CB  . SER   A 1 182 ? 8.79700   31.62800 4.34400   1.000 42.18445  ? 182 SER   H CB  1 
ATOM   1342 O  OG  . SER   A 1 182 ? 9.20900   31.15100 5.61300   1.000 53.94953  ? 182 SER   H OG  1 
ATOM   1343 N  N   . SER   A 1 183 ? 10.88100  29.30100 3.00800   1.000 45.30074  ? 183 SER   H N   1 
ATOM   1344 C  CA  . SER   A 1 183 ? 12.10600  28.96400 2.29300   1.000 45.72850  ? 183 SER   H CA  1 
ATOM   1345 C  C   . SER   A 1 183 ? 11.85900  28.81400 0.79900   1.000 46.98500  ? 183 SER   H C   1 
ATOM   1346 O  O   . SER   A 1 183 ? 12.75300  29.08200 -0.01300  1.000 43.89539  ? 183 SER   H O   1 
ATOM   1347 C  CB  . SER   A 1 183 ? 12.68800  27.66000 2.84300   1.000 53.73070  ? 183 SER   H CB  1 
ATOM   1348 O  OG  . SER   A 1 183 ? 12.77200  27.68300 4.25600   1.000 55.74570  ? 183 SER   H OG  1 
ATOM   1349 N  N   . GLY   A 1 184 ? 10.64600  28.41900 0.41900   1.000 44.58765  ? 184 GLY   H N   1 
ATOM   1350 C  CA  . GLY   A 1 184 ? 10.38100  27.89400 -0.89600  1.000 41.95118  ? 184 GLY   H CA  1 
ATOM   1351 C  C   . GLY   A 1 184 ? 10.55500  26.39800 -0.98800  1.000 41.36870  ? 184 GLY   H C   1 
ATOM   1352 O  O   . GLY   A 1 184 ? 10.24800  25.81500 -2.03500  1.000 37.08461  ? 184 GLY   H O   1 
ATOM   1353 N  N   . LEU   A 1 185 ? 11.03800  25.76400 0.07600   1.000 41.86165  ? 185 LEU   H N   1 
ATOM   1354 C  CA  . LEU   A 1 185 ? 11.26200  24.32900 0.13800   1.000 42.80991  ? 185 LEU   H CA  1 
ATOM   1355 C  C   . LEU   A 1 185 ? 10.13500  23.65000 0.90700   1.000 42.53799  ? 185 LEU   H C   1 
ATOM   1356 O  O   . LEU   A 1 185 ? 9.46100   24.26000 1.74100   1.000 39.06250  ? 185 LEU   H O   1 
ATOM   1357 C  CB  . LEU   A 1 185 ? 12.60700  24.02300 0.80200   1.000 43.94844  ? 185 LEU   H CB  1 
ATOM   1358 C  CG  . LEU   A 1 185 ? 13.80300  24.79100 0.23900   1.000 41.89159  ? 185 LEU   H CG  1 
ATOM   1359 C  CD1 . LEU   A 1 185 ? 14.97700  24.74100 1.20100   1.000 43.75086  ? 185 LEU   H CD1 1 
ATOM   1360 C  CD2 . LEU   A 1 185 ? 14.19500  24.24000 -1.12200  1.000 39.80894  ? 185 LEU   H CD2 1 
ATOM   1361 N  N   . TYR   A 1 186 ? 9.94300   22.36800 0.61700   1.000 40.49881  ? 186 TYR   H N   1 
ATOM   1362 C  CA  . TYR   A 1 186 ? 8.87400   21.59000 1.22100   1.000 35.71169  ? 186 TYR   H CA  1 
ATOM   1363 C  C   . TYR   A 1 186 ? 9.38200   20.82900 2.44000   1.000 40.61921  ? 186 TYR   H C   1 
ATOM   1364 O  O   . TYR   A 1 186 ? 10.57900  20.58500 2.60200   1.000 41.32710  ? 186 TYR   H O   1 
ATOM   1365 C  CB  . TYR   A 1 186 ? 8.28400   20.61200 0.20700   1.000 34.08181  ? 186 TYR   H CB  1 
ATOM   1366 C  CG  . TYR   A 1 186 ? 7.49900   21.27700 -0.89700  1.000 39.99782  ? 186 TYR   H CG  1 
ATOM   1367 C  CD1 . TYR   A 1 186 ? 6.15200   21.57300 -0.73700  1.000 42.46143  ? 186 TYR   H CD1 1 
ATOM   1368 C  CD2 . TYR   A 1 186 ? 8.10600   21.61300 -2.09900  1.000 40.28230  ? 186 TYR   H CD2 1 
ATOM   1369 C  CE1 . TYR   A 1 186 ? 5.43000   22.18300 -1.74600  1.000 43.29429  ? 186 TYR   H CE1 1 
ATOM   1370 C  CE2 . TYR   A 1 186 ? 7.39300   22.22300 -3.11400  1.000 40.68132  ? 186 TYR   H CE2 1 
ATOM   1371 C  CZ  . TYR   A 1 186 ? 6.05600   22.50600 -2.93200  1.000 42.07913  ? 186 TYR   H CZ  1 
ATOM   1372 O  OH  . TYR   A 1 186 ? 5.34500   23.11300 -3.94300  1.000 36.35703  ? 186 TYR   H OH  1 
ATOM   1373 N  N   . SER   A 1 187 ? 8.44300   20.45300 3.30400   1.000 42.11484  ? 187 SER   H N   1 
ATOM   1374 C  CA  . SER   A 1 187 ? 8.76400   19.69100 4.49900   1.000 41.25031  ? 187 SER   H CA  1 
ATOM   1375 C  C   . SER   A 1 187 ? 7.53500   18.90600 4.92400   1.000 39.76631  ? 187 SER   H C   1 
ATOM   1376 O  O   . SER   A 1 187 ? 6.39900   19.33200 4.69300   1.000 40.91563  ? 187 SER   H O   1 
ATOM   1377 C  CB  . SER   A 1 187 ? 9.23400   20.59600 5.64400   1.000 39.63032  ? 187 SER   H CB  1 
ATOM   1378 O  OG  . SER   A 1 187 ? 9.64100   19.83100 6.76600   1.000 47.24890  ? 187 SER   H OG  1 
ATOM   1379 N  N   . LEU   A 1 188 ? 7.77300   17.75500 5.54600   1.000 40.67606  ? 188 LEU   H N   1 
ATOM   1380 C  CA  . LEU   A 1 188 ? 6.68400   16.93400 6.05200   1.000 39.62462  ? 188 LEU   H CA  1 
ATOM   1381 C  C   . LEU   A 1 188 ? 7.18400   16.07600 7.20500   1.000 40.40433  ? 188 LEU   H C   1 
ATOM   1382 O  O   . LEU   A 1 188 ? 8.38700   15.86600 7.37900   1.000 37.66880  ? 188 LEU   H O   1 
ATOM   1383 C  CB  . LEU   A 1 188 ? 6.08000   16.04200 4.95800   1.000 31.28748  ? 188 LEU   H CB  1 
ATOM   1384 C  CG  . LEU   A 1 188 ? 7.01100   15.22500 4.06200   1.000 35.54615  ? 188 LEU   H CG  1 
ATOM   1385 C  CD1 . LEU   A 1 188 ? 7.34900   13.88000 4.68700   1.000 42.63206  ? 188 LEU   H CD1 1 
ATOM   1386 C  CD2 . LEU   A 1 188 ? 6.33600   15.02200 2.72600   1.000 38.77377  ? 188 LEU   H CD2 1 
ATOM   1387 N  N   . SER   A 1 189 ? 6.23300   15.58300 7.99100   1.000 39.84967  ? 189 SER   H N   1 
ATOM   1388 C  CA  . SER   A 1 189 ? 6.49000   14.60100 9.03000   1.000 39.64723  ? 189 SER   H CA  1 
ATOM   1389 C  C   . SER   A 1 189 ? 5.69300   13.34200 8.72600   1.000 37.06888  ? 189 SER   H C   1 
ATOM   1390 O  O   . SER   A 1 189 ? 4.61700   13.39900 8.12400   1.000 35.35132  ? 189 SER   H O   1 
ATOM   1391 C  CB  . SER   A 1 189 ? 6.11000   15.13100 10.42200  1.000 37.97432  ? 189 SER   H CB  1 
ATOM   1392 O  OG  . SER   A 1 189 ? 6.37300   16.51900 10.53600  1.000 49.46362  ? 189 SER   H OG  1 
ATOM   1393 N  N   . SER   A 1 190 ? 6.24000   12.20100 9.13200   1.000 38.12200  ? 190 SER   H N   1 
ATOM   1394 C  CA  . SER   A 1 190 ? 5.53400   10.92800 9.08900   1.000 37.34534  ? 190 SER   H CA  1 
ATOM   1395 C  C   . SER   A 1 190 ? 5.67400   10.28700 10.45700  1.000 36.26998  ? 190 SER   H C   1 
ATOM   1396 O  O   . SER   A 1 190 ? 6.79500   10.05300 10.91600  1.000 44.62753  ? 190 SER   H O   1 
ATOM   1397 C  CB  . SER   A 1 190 ? 6.09200   10.01200 8.00000   1.000 42.82279  ? 190 SER   H CB  1 
ATOM   1398 O  OG  . SER   A 1 190 ? 5.41900   8.76500  7.99400   1.000 39.23370  ? 190 SER   H OG  1 
ATOM   1399 N  N   . VAL   A 1 191 ? 4.54800   10.01700 11.11200  1.000 33.71670  ? 191 VAL   H N   1 
ATOM   1400 C  CA  . VAL   A 1 191 ? 4.56000   9.58400  12.50100  1.000 38.19975  ? 191 VAL   H CA  1 
ATOM   1401 C  C   . VAL   A 1 191 ? 3.87300   8.23100  12.62500  1.000 37.72102  ? 191 VAL   H C   1 
ATOM   1402 O  O   . VAL   A 1 191 ? 3.10300   7.80900  11.76000  1.000 38.32224  ? 191 VAL   H O   1 
ATOM   1403 C  CB  . VAL   A 1 191 ? 3.89200   10.61500 13.43300  1.000 37.87996  ? 191 VAL   H CB  1 
ATOM   1404 C  CG1 . VAL   A 1 191 ? 4.46400   12.00300 13.18400  1.000 30.22848  ? 191 VAL   H CG1 1 
ATOM   1405 C  CG2 . VAL   A 1 191 ? 2.38600   10.60900 13.22500  1.000 33.06630  ? 191 VAL   H CG2 1 
ATOM   1406 N  N   . VAL   A 1 192 ? 4.17700   7.54700  13.72500  1.000 39.68350  ? 192 VAL   H N   1 
ATOM   1407 C  CA  . VAL   A 1 192 ? 3.55800   6.27300  14.06600  1.000 37.59361  ? 192 VAL   H CA  1 
ATOM   1408 C  C   . VAL   A 1 192 ? 3.15900   6.31400  15.53300  1.000 38.56233  ? 192 VAL   H C   1 
ATOM   1409 O  O   . VAL   A 1 192 ? 3.91500   6.80500  16.37700  1.000 47.06814  ? 192 VAL   H O   1 
ATOM   1410 C  CB  . VAL   A 1 192 ? 4.50400   5.08100  13.80400  1.000 44.09737  ? 192 VAL   H CB  1 
ATOM   1411 C  CG1 . VAL   A 1 192 ? 3.78300   3.76700  14.06100  1.000 42.54013  ? 192 VAL   H CG1 1 
ATOM   1412 C  CG2 . VAL   A 1 192 ? 5.05300   5.12000  12.38500  1.000 43.82942  ? 192 VAL   H CG2 1 
ATOM   1413 N  N   . THR   A 1 193 ? 1.97200   5.79800  15.83700  1.000 38.50793  ? 193 THR   H N   1 
ATOM   1414 C  CA  . THR   A 1 193 ? 1.54300   5.58800  17.21200  1.000 39.38259  ? 193 THR   H CA  1 
ATOM   1415 C  C   . THR   A 1 193 ? 1.70900   4.11700  17.55900  1.000 43.21444  ? 193 THR   H C   1 
ATOM   1416 O  O   . THR   A 1 193 ? 1.29000   3.24100  16.79700  1.000 45.77949  ? 193 THR   H O   1 
ATOM   1417 C  CB  . THR   A 1 193 ? 0.09200   6.02300  17.41700  1.000 39.90137  ? 193 THR   H CB  1 
ATOM   1418 O  OG1 . THR   A 1 193 ? -0.67300  5.70800  16.24800  1.000 47.51444  ? 193 THR   H OG1 1 
ATOM   1419 C  CG2 . THR   A 1 193 ? 0.01500   7.51700  17.68000  1.000 42.33506  ? 193 THR   H CG2 1 
ATOM   1420 N  N   . VAL   A 1 194 ? 2.34000   3.85000  18.70100  1.000 44.54515  ? 194 VAL   H N   1 
ATOM   1421 C  CA  . VAL   A 1 194 ? 2.60600   2.47600  19.12600  1.000 42.67517  ? 194 VAL   H CA  1 
ATOM   1422 C  C   . VAL   A 1 194 ? 2.33100   2.34700  20.60600  1.000 43.62933  ? 194 VAL   H C   1 
ATOM   1423 O  O   . VAL   A 1 194 ? 2.35900   3.33100  21.36400  1.000 42.73190  ? 194 VAL   H O   1 
ATOM   1424 C  CB  . VAL   A 1 194 ? 4.06400   2.05800  18.83700  1.000 39.96210  ? 194 VAL   H CB  1 
ATOM   1425 C  CG1 . VAL   A 1 194 ? 4.34100   2.04600  17.33900  1.000 43.77489  ? 194 VAL   H CG1 1 
ATOM   1426 C  CG2 . VAL   A 1 194 ? 5.03700   2.98000  19.56000  1.000 40.71845  ? 194 VAL   H CG2 1 
ATOM   1427 N  N   . PRO   A 1 195 ? 2.03900   1.12900  21.05900  1.000 50.54832  ? 195 PRO   H N   1 
ATOM   1428 C  CA  . PRO   A 1 195 ? 2.09600   0.85300  22.49600  1.000 43.32933  ? 195 PRO   H CA  1 
ATOM   1429 C  C   . PRO   A 1 195 ? 3.50000   1.11100  23.01800  1.000 47.03871  ? 195 PRO   H C   1 
ATOM   1430 O  O   . PRO   A 1 195 ? 4.49200   0.82000  22.34700  1.000 48.44609  ? 195 PRO   H O   1 
ATOM   1431 C  CB  . PRO   A 1 195 ? 1.72100   -0.62900 22.59000  1.000 39.61232  ? 195 PRO   H CB  1 
ATOM   1432 C  CG  . PRO   A 1 195 ? 0.95200   -0.90600 21.34800  1.000 40.09102  ? 195 PRO   H CG  1 
ATOM   1433 C  CD  . PRO   A 1 195 ? 1.56000   -0.03400 20.29100  1.000 42.79361  ? 195 PRO   H CD  1 
ATOM   1434 N  N   . SER   A 1 196 ? 3.57600   1.66600  24.22900  1.000 46.97823  ? 196 SER   H N   1 
ATOM   1435 C  CA  . SER   A 1 196 ? 4.86700   2.06700  24.77700  1.000 46.83610  ? 196 SER   H CA  1 
ATOM   1436 C  C   . SER   A 1 196 ? 5.81000   0.87900  24.91900  1.000 46.70916  ? 196 SER   H C   1 
ATOM   1437 O  O   . SER   A 1 196 ? 7.01300   0.99700  24.65700  1.000 50.83763  ? 196 SER   H O   1 
ATOM   1438 C  CB  . SER   A 1 196 ? 4.66600   2.75900  26.12400  1.000 44.44354  ? 196 SER   H CB  1 
ATOM   1439 O  OG  . SER   A 1 196 ? 4.01700   4.00700  25.95700  1.000 56.63023  ? 196 SER   H OG  1 
ATOM   1440 N  N   . SER   A 1 197 ? 5.28200   -0.28100 25.31500  1.000 50.29908  ? 197 SER   H N   1 
ATOM   1441 C  CA  . SER   A 1 197 ? 6.15100   -1.41400 25.61600  1.000 55.38700  ? 197 SER   H CA  1 
ATOM   1442 C  C   . SER   A 1 197 ? 6.87300   -1.92800 24.37600  1.000 50.47736  ? 197 SER   H C   1 
ATOM   1443 O  O   . SER   A 1 197 ? 8.00900   -2.40600 24.48000  1.000 58.20325  ? 197 SER   H O   1 
ATOM   1444 C  CB  . SER   A 1 197 ? 5.34300   -2.53400 26.27000  1.000 51.04866  ? 197 SER   H CB  1 
ATOM   1445 O  OG  . SER   A 1 197 ? 4.40200   -2.00000 27.18400  1.000 52.63052  ? 197 SER   H OG  1 
ATOM   1446 N  N   . SER   A 1 198 ? 6.25300   -1.82200 23.19900  1.000 49.39221  ? 198 SER   H N   1 
ATOM   1447 C  CA  . SER   A 1 198 ? 6.86200   -2.33000 21.97400  1.000 51.60421  ? 198 SER   H CA  1 
ATOM   1448 C  C   . SER   A 1 198 ? 8.02400   -1.47700 21.48700  1.000 52.55607  ? 198 SER   H C   1 
ATOM   1449 O  O   . SER   A 1 198 ? 8.58600   -1.78400 20.42900  1.000 59.54120  ? 198 SER   H O   1 
ATOM   1450 C  CB  . SER   A 1 198 ? 5.80800   -2.45200 20.87200  1.000 50.15388  ? 198 SER   H CB  1 
ATOM   1451 O  OG  . SER   A 1 198 ? 5.52500   -1.19200 20.28700  1.000 49.99450  ? 198 SER   H OG  1 
ATOM   1452 N  N   . LEU   A 1 199 ? 8.39300   -0.42100 22.21700  1.000 51.78441  ? 199 LEU   H N   1 
ATOM   1453 C  CA  . LEU   A 1 199 ? 9.62000   0.30000  21.91100  1.000 50.63856  ? 199 LEU   H CA  1 
ATOM   1454 C  C   . LEU   A 1 199 ? 10.85400  -0.55900 22.13900  1.000 55.10202  ? 199 LEU   H C   1 
ATOM   1455 O  O   . LEU   A 1 199 ? 11.90500  -0.28500 21.55000  1.000 56.29081  ? 199 LEU   H O   1 
ATOM   1456 C  CB  . LEU   A 1 199 ? 9.70700   1.57700  22.74900  1.000 52.65889  ? 199 LEU   H CB  1 
ATOM   1457 C  CG  . LEU   A 1 199 ? 8.67400   2.65800  22.43100  1.000 49.81961  ? 199 LEU   H CG  1 
ATOM   1458 C  CD1 . LEU   A 1 199 ? 8.87700   3.87800  23.31900  1.000 46.90047  ? 199 LEU   H CD1 1 
ATOM   1459 C  CD2 . LEU   A 1 199 ? 8.73900   3.03600  20.96100  1.000 37.15431  ? 199 LEU   H CD2 1 
ATOM   1460 N  N   . GLY   A 1 200 ? 10.74800  -1.59500 22.96500  1.000 60.55356  ? 200 GLY   H N   1 
ATOM   1461 C  CA  . GLY   A 1 200 ? 11.86200  -2.49300 23.18800  1.000 60.10254  ? 200 GLY   H CA  1 
ATOM   1462 C  C   . GLY   A 1 200 ? 11.81800  -3.72000 22.30200  1.000 52.69594  ? 200 GLY   H C   1 
ATOM   1463 O  O   . GLY   A 1 200 ? 12.85700  -4.31600 22.00400  1.000 54.17640  ? 200 GLY   H O   1 
ATOM   1464 N  N   . THR   A 1 201 ? 10.62000  -4.09900 21.86000  1.000 54.69673  ? 201 THR   H N   1 
ATOM   1465 C  CA  . THR   A 1 201 ? 10.42000  -5.33900 21.12400  1.000 56.80214  ? 201 THR   H CA  1 
ATOM   1466 C  C   . THR   A 1 201 ? 10.33200  -5.13900 19.61600  1.000 56.10185  ? 201 THR   H C   1 
ATOM   1467 O  O   . THR   A 1 201 ? 10.01200  -6.09100 18.89700  1.000 57.93771  ? 201 THR   H O   1 
ATOM   1468 C  CB  . THR   A 1 201 ? 9.16200   -6.05000 21.62600  1.000 54.88381  ? 201 THR   H CB  1 
ATOM   1469 O  OG1 . THR   A 1 201 ? 8.01400   -5.23300 21.36700  1.000 58.96758  ? 201 THR   H OG1 1 
ATOM   1470 C  CG2 . THR   A 1 201 ? 9.25800   -6.29800 23.12200  1.000 48.90381  ? 201 THR   H CG2 1 
ATOM   1471 N  N   . GLN   A 1 202 ? 10.60000  -3.93300 19.12100  1.000 53.74927  ? 202 GLN   H N   1 
ATOM   1472 C  CA  . GLN   A 1 202 ? 10.64800  -3.69700 17.68500  1.000 45.27324  ? 202 GLN   H CA  1 
ATOM   1473 C  C   . GLN   A 1 202 ? 11.56400  -2.51600 17.41000  1.000 44.56137  ? 202 GLN   H C   1 
ATOM   1474 O  O   . GLN   A 1 202 ? 11.70200  -1.61600 18.24300  1.000 47.08816  ? 202 GLN   H O   1 
ATOM   1475 C  CB  . GLN   A 1 202 ? 9.25700   -3.42500 17.09600  1.000 45.12342  ? 202 GLN   H CB  1 
ATOM   1476 C  CG  . GLN   A 1 202 ? 8.31600   -4.62600 17.08900  1.000 59.05618  ? 202 GLN   H CG  1 
ATOM   1477 C  CD  . GLN   A 1 202 ? 6.91900   -4.26300 17.54000  1.000 64.04703  ? 202 GLN   H CD  1 
ATOM   1478 O  OE1 . GLN   A 1 202 ? 6.68000   -3.16300 18.03700  1.000 71.83452  ? 202 GLN   H OE1 1 
ATOM   1479 N  NE2 . GLN   A 1 202 ? 5.98100   -5.18200 17.35200  1.000 52.43507  ? 202 GLN   H NE2 1 
ATOM   1480 N  N   . THR   A 1 203 ? 12.17800  -2.52400 16.23100  1.000 51.32760  ? 203 THR   H N   1 
ATOM   1481 C  CA  . THR   A 1 203 ? 12.93600  -1.38400 15.73800  1.000 54.80025  ? 203 THR   H CA  1 
ATOM   1482 C  C   . THR   A 1 203 ? 12.13800  -0.68800 14.64600  1.000 49.91072  ? 203 THR   H C   1 
ATOM   1483 O  O   . THR   A 1 203 ? 11.46900  -1.34000 13.83800  1.000 48.88779  ? 203 THR   H O   1 
ATOM   1484 C  CB  . THR   A 1 203 ? 14.30300  -1.80700 15.19600  1.000 51.98843  ? 203 THR   H CB  1 
ATOM   1485 O  OG1 . THR   A 1 203 ? 14.13200  -2.54000 13.97700  1.000 57.20796  ? 203 THR   H OG1 1 
ATOM   1486 C  CG2 . THR   A 1 203 ? 15.04500  -2.66600 16.20700  1.000 51.40125  ? 203 THR   H CG2 1 
ATOM   1487 N  N   . TYR   A 1 204 ? 12.20300  0.63800  14.63200  1.000 52.72037  ? 204 TYR   H N   1 
ATOM   1488 C  CA  . TYR   A 1 204 ? 11.41600  1.45800  13.71800  1.000 47.52702  ? 204 TYR   H CA  1 
ATOM   1489 C  C   . TYR   A 1 204 ? 12.36600  2.22500  12.80800  1.000 47.41441  ? 204 TYR   H C   1 
ATOM   1490 O  O   . TYR   A 1 204 ? 13.07500  3.12900  13.26200  1.000 51.13837  ? 204 TYR   H O   1 
ATOM   1491 C  CB  . TYR   A 1 204 ? 10.50500  2.40400  14.49800  1.000 41.21000  ? 204 TYR   H CB  1 
ATOM   1492 C  CG  . TYR   A 1 204 ? 9.46800   1.68500  15.32700  1.000 45.26899  ? 204 TYR   H CG  1 
ATOM   1493 C  CD1 . TYR   A 1 204 ? 8.28100   1.25000  14.75600  1.000 44.50679  ? 204 TYR   H CD1 1 
ATOM   1494 C  CD2 . TYR   A 1 204 ? 9.68200   1.42500  16.67500  1.000 45.45438  ? 204 TYR   H CD2 1 
ATOM   1495 C  CE1 . TYR   A 1 204 ? 7.33000   0.58600  15.50300  1.000 45.22275  ? 204 TYR   H CE1 1 
ATOM   1496 C  CE2 . TYR   A 1 204 ? 8.73600   0.76000  17.43200  1.000 40.77478  ? 204 TYR   H CE2 1 
ATOM   1497 C  CZ  . TYR   A 1 204 ? 7.56200   0.34300  16.84100  1.000 41.39034  ? 204 TYR   H CZ  1 
ATOM   1498 O  OH  . TYR   A 1 204 ? 6.62200   -0.31900 17.59600  1.000 44.86846  ? 204 TYR   H OH  1 
ATOM   1499 N  N   . ILE   A 1 205 ? 12.37100  1.87000  11.52600  1.000 51.42518  ? 205 ILE   H N   1 
ATOM   1500 C  CA  . ILE   A 1 205 ? 13.21400  2.50500  10.52000  1.000 52.53056  ? 205 ILE   H CA  1 
ATOM   1501 C  C   . ILE   A 1 205 ? 12.30700  3.16300  9.48800   1.000 50.42657  ? 205 ILE   H C   1 
ATOM   1502 O  O   . ILE   A 1 205 ? 11.50400  2.48100  8.83700   1.000 51.92544  ? 205 ILE   H O   1 
ATOM   1503 C  CB  . ILE   A 1 205 ? 14.15600  1.49000  9.85300   1.000 52.85137  ? 205 ILE   H CB  1 
ATOM   1504 C  CG1 . ILE   A 1 205 ? 15.09600  0.85800  10.88300  1.000 55.30534  ? 205 ILE   H CG1 1 
ATOM   1505 C  CG2 . ILE   A 1 205 ? 14.91300  2.13000  8.71500   1.000 51.10812  ? 205 ILE   H CG2 1 
ATOM   1506 C  CD1 . ILE   A 1 205 ? 15.94200  -0.26000 10.32200  1.000 56.63532  ? 205 ILE   H CD1 1 
ATOM   1507 N  N   . CYS   A 1 206 ? 12.42900  4.48000  9.34100   1.000 51.48462  ? 206 CYS   H N   1 
ATOM   1508 C  CA  . CYS   A 1 206 ? 11.68300  5.21200  8.32700   1.000 50.49766  ? 206 CYS   H CA  1 
ATOM   1509 C  C   . CYS   A 1 206 ? 12.51000  5.26400  7.04800   1.000 43.19303  ? 206 CYS   H C   1 
ATOM   1510 O  O   . CYS   A 1 206 ? 13.71200  5.53900  7.09700   1.000 43.39850  ? 206 CYS   H O   1 
ATOM   1511 C  CB  . CYS   A 1 206 ? 11.32700  6.61300  8.83000   1.000 43.56750  ? 206 CYS   H CB  1 
ATOM   1512 S  SG  . CYS   A 1 206 ? 12.56000  7.87100  8.58000   1.000 57.85719  ? 206 CYS   H SG  1 
ATOM   1513 N  N   . ASN   A 1 207 ? 11.87700  4.94500  5.91200   1.000 40.72262  ? 207 ASN   H N   1 
ATOM   1514 C  CA  . ASN   A 1 207 ? 12.51800  4.92800  4.59600   1.000 39.87121  ? 207 ASN   H CA  1 
ATOM   1515 C  C   . ASN   A 1 207 ? 11.96000  6.10700  3.81300   1.000 37.25129  ? 207 ASN   H C   1 
ATOM   1516 O  O   . ASN   A 1 207 ? 10.78100  6.11000  3.44500   1.000 35.96494  ? 207 ASN   H O   1 
ATOM   1517 C  CB  . ASN   A 1 207 ? 12.26600  3.60500  3.86900   1.000 43.32031  ? 207 ASN   H CB  1 
ATOM   1518 C  CG  . ASN   A 1 207 ? 12.20700  2.43400  4.81400   1.000 45.72207  ? 207 ASN   H CG  1 
ATOM   1519 O  OD1 . ASN   A 1 207 ? 11.12900  1.99200  5.20800   1.000 47.15564  ? 207 ASN   H OD1 1 
ATOM   1520 N  ND2 . ASN   A 1 207 ? 13.37000  1.94600  5.21600   1.000 52.43325  ? 207 ASN   H ND2 1 
ATOM   1521 N  N   . VAL   A 1 208 ? 12.78900  7.12100  3.59800   1.000 37.51555  ? 208 VAL   H N   1 
ATOM   1522 C  CA  . VAL   A 1 208 ? 12.40000  8.32100  2.86700   1.000 43.38973  ? 208 VAL   H CA  1 
ATOM   1523 C  C   . VAL   A 1 208 ? 13.00000  8.24800  1.47500   1.000 46.63383  ? 208 VAL   H C   1 
ATOM   1524 O  O   . VAL   A 1 208 ? 14.15200  7.83100  1.30300   1.000 46.48967  ? 208 VAL   H O   1 
ATOM   1525 C  CB  . VAL   A 1 208 ? 12.85900  9.59400  3.60000   1.000 42.71384  ? 208 VAL   H CB  1 
ATOM   1526 C  CG1 . VAL   A 1 208 ? 12.47600  10.83500 2.80400   1.000 41.07530  ? 208 VAL   H CG1 1 
ATOM   1527 C  CG2 . VAL   A 1 208 ? 12.26700  9.63300  4.98800   1.000 33.40572  ? 208 VAL   H CG2 1 
ATOM   1528 N  N   . ASN   A 1 209 ? 12.22200  8.65000  0.47700   1.000 46.58155  ? 209 ASN   H N   1 
ATOM   1529 C  CA  . ASN   A 1 209 ? 12.61900  8.53100  -0.91500  1.000 48.03133  ? 209 ASN   H CA  1 
ATOM   1530 C  C   . ASN   A 1 209 ? 12.30000  9.83100  -1.63300  1.000 46.64690  ? 209 ASN   H C   1 
ATOM   1531 O  O   . ASN   A 1 209 ? 11.16300  10.30800 -1.58300  1.000 47.23474  ? 209 ASN   H O   1 
ATOM   1532 C  CB  . ASN   A 1 209 ? 11.90500  7.35300  -1.58000  1.000 51.66007  ? 209 ASN   H CB  1 
ATOM   1533 C  CG  . ASN   A 1 209 ? 12.37300  7.11600  -2.98700  1.000 52.03891  ? 209 ASN   H CG  1 
ATOM   1534 O  OD1 . ASN   A 1 209 ? 13.36400  6.42900  -3.22700  1.000 57.64863  ? 209 ASN   H OD1 1 
ATOM   1535 N  ND2 . ASN   A 1 209 ? 11.66300  7.69800  -3.93500  1.000 50.64811  ? 209 ASN   H ND2 1 
ATOM   1536 N  N   . HIS   A 1 210 ? 13.31500  10.41100 -2.28300  1.000 45.57443  ? 210 HIS   H N   1 
ATOM   1537 C  CA  . HIS   A 1 210 ? 13.18700  11.65100 -3.05300  1.000 38.76584  ? 210 HIS   H CA  1 
ATOM   1538 C  C   . HIS   A 1 210 ? 13.80500  11.39600 -4.42800  1.000 45.91780  ? 210 HIS   H C   1 
ATOM   1539 O  O   . HIS   A 1 210 ? 14.93800  11.80400 -4.69400  1.000 44.34302  ? 210 HIS   H O   1 
ATOM   1540 C  CB  . HIS   A 1 210 ? 13.85900  12.83000 -2.32400  1.000 42.03890  ? 210 HIS   H CB  1 
ATOM   1541 C  CG  . HIS   A 1 210 ? 13.52600  14.17500 -2.90000  1.000 48.42992  ? 210 HIS   H CG  1 
ATOM   1542 N  ND1 . HIS   A 1 210 ? 14.48400  15.12700 -3.17700  1.000 47.61161  ? 210 HIS   H ND1 1 
ATOM   1543 C  CD2 . HIS   A 1 210 ? 12.34000  14.72500 -3.25200  1.000 43.90110  ? 210 HIS   H CD2 1 
ATOM   1544 C  CE1 . HIS   A 1 210 ? 13.90200  16.20600 -3.66800  1.000 45.59411  ? 210 HIS   H CE1 1 
ATOM   1545 N  NE2 . HIS   A 1 210 ? 12.60100  15.98800 -3.72400  1.000 42.42727  ? 210 HIS   H NE2 1 
ATOM   1546 N  N   . LYS   A 1 211 ? 13.05800  10.70800 -5.29200  1.000 48.48033  ? 211 LYS   H N   1 
ATOM   1547 C  CA  . LYS   A 1 211 ? 13.52700  10.48500 -6.65700  1.000 45.57131  ? 211 LYS   H CA  1 
ATOM   1548 C  C   . LYS   A 1 211 ? 13.90700  11.76300 -7.40300  1.000 48.80322  ? 211 LYS   H C   1 
ATOM   1549 O  O   . LYS   A 1 211 ? 14.85300  11.69900 -8.20700  1.000 53.99609  ? 211 LYS   H O   1 
ATOM   1550 C  CB  . LYS   A 1 211 ? 12.47100  9.70500  -7.45900  1.000 39.10676  ? 211 LYS   H CB  1 
ATOM   1551 C  CG  . LYS   A 1 211 ? 12.09800  8.36100  -6.86900  1.000 51.02087  ? 211 LYS   H CG  1 
ATOM   1552 C  CD  . LYS   A 1 211 ? 12.08200  7.25300  -7.90300  1.000 60.91243  ? 211 LYS   H CD  1 
ATOM   1553 C  CE  . LYS   A 1 211 ? 10.99600  6.22900  -7.58000  1.000 58.39862  ? 211 LYS   H CE  1 
ATOM   1554 N  NZ  . LYS   A 1 211 ? 11.53100  5.01900  -6.89600  1.000 46.99181  ? 211 LYS   H NZ  1 
ATOM   1555 N  N   . PRO   A 1 212 ? 13.25100  12.92900 -7.20800  1.000 45.68227  ? 212 PRO   H N   1 
ATOM   1556 C  CA  . PRO   A 1 212 ? 13.73400  14.15000 -7.87500  1.000 42.54795  ? 212 PRO   H CA  1 
ATOM   1557 C  C   . PRO   A 1 212 ? 15.20400  14.46900 -7.62900  1.000 43.41486  ? 212 PRO   H C   1 
ATOM   1558 O  O   . PRO   A 1 212 ? 15.77300  15.32300 -8.31500  1.000 51.95496  ? 212 PRO   H O   1 
ATOM   1559 C  CB  . PRO   A 1 212 ? 12.82800  15.23700 -7.29200  1.000 40.33094  ? 212 PRO   H CB  1 
ATOM   1560 C  CG  . PRO   A 1 212 ? 11.54900  14.53900 -7.05800  1.000 37.48145  ? 212 PRO   H CG  1 
ATOM   1561 C  CD  . PRO   A 1 212 ? 11.90600  13.13500 -6.63200  1.000 43.65682  ? 212 PRO   H CD  1 
ATOM   1562 N  N   . SER   A 1 213 ? 15.82900  13.80000 -6.65500  1.000 43.89129  ? 213 SER   H N   1 
ATOM   1563 C  CA  . SER   A 1 213 ? 17.26000  13.96700 -6.43100  1.000 43.89445  ? 213 SER   H CA  1 
ATOM   1564 C  C   . SER   A 1 213 ? 17.95600  12.63800 -6.14600  1.000 47.99664  ? 213 SER   H C   1 
ATOM   1565 O  O   . SER   A 1 213 ? 19.09700  12.64100 -5.66800  1.000 51.25274  ? 213 SER   H O   1 
ATOM   1566 C  CB  . SER   A 1 213 ? 17.52300  14.94800 -5.28200  1.000 47.11958  ? 213 SER   H CB  1 
ATOM   1567 O  OG  . SER   A 1 213 ? 16.90800  14.51000 -4.08300  1.000 46.58434  ? 213 SER   H OG  1 
ATOM   1568 N  N   . ASN   A 1 214 ? 17.29900  11.50800 -6.42900  1.000 52.26262  ? 214 ASN   H N   1 
ATOM   1569 C  CA  . ASN   A 1 214 ? 17.85700  10.17400 -6.18700  1.000 51.66598  ? 214 ASN   H CA  1 
ATOM   1570 C  C   . ASN   A 1 214 ? 18.25300  9.99100  -4.72300  1.000 50.78898  ? 214 ASN   H C   1 
ATOM   1571 O  O   . ASN   A 1 214 ? 19.24800  9.33600  -4.40500  1.000 60.47057  ? 214 ASN   H O   1 
ATOM   1572 C  CB  . ASN   A 1 214 ? 19.04300  9.88700  -7.11100  1.000 53.62830  ? 214 ASN   H CB  1 
ATOM   1573 C  CG  . ASN   A 1 214 ? 18.66100  9.92700  -8.57800  1.000 61.93330  ? 214 ASN   H CG  1 
ATOM   1574 O  OD1 . ASN   A 1 214 ? 17.64300  9.36300  -8.98100  1.000 59.91753  ? 214 ASN   H OD1 1 
ATOM   1575 N  ND2 . ASN   A 1 214 ? 19.47800  10.59300 -9.38400  1.000 64.37855  ? 214 ASN   H ND2 1 
ATOM   1576 N  N   . THR   A 1 215 ? 17.46500  10.57200 -3.82400  1.000 44.05383  ? 215 THR   H N   1 
ATOM   1577 C  CA  . THR   A 1 215 ? 17.72200  10.47900 -2.39500  1.000 45.50179  ? 215 THR   H CA  1 
ATOM   1578 C  C   . THR   A 1 215 ? 16.96400  9.29500  -1.81000  1.000 48.60017  ? 215 THR   H C   1 
ATOM   1579 O  O   . THR   A 1 215 ? 15.75600  9.15300  -2.02200  1.000 48.66435  ? 215 THR   H O   1 
ATOM   1580 C  CB  . THR   A 1 215 ? 17.31300  11.76700 -1.68000  1.000 44.06598  ? 215 THR   H CB  1 
ATOM   1581 O  OG1 . THR   A 1 215 ? 18.08900  12.86300 -2.17900  1.000 50.95372  ? 215 THR   H OG1 1 
ATOM   1582 C  CG2 . THR   A 1 215 ? 17.53900  11.63500 -0.18400  1.000 39.19458  ? 215 THR   H CG2 1 
ATOM   1583 N  N   . LYS   A 1 216 ? 17.68300  8.44100  -1.08800  1.000 44.71367  ? 216 LYS   H N   1 
ATOM   1584 C  CA  . LYS   A 1 216 ? 17.08300  7.36000  -0.31600  1.000 40.92167  ? 216 LYS   H CA  1 
ATOM   1585 C  C   . LYS   A 1 216 ? 17.67700  7.40400  1.08100   1.000 50.06000  ? 216 LYS   H C   1 
ATOM   1586 O  O   . LYS   A 1 216 ? 18.89500  7.27400  1.24300   1.000 54.73396  ? 216 LYS   H O   1 
ATOM   1587 C  CB  . LYS   A 1 216 ? 17.32100  5.99700  -0.97500  1.000 48.79693  ? 216 LYS   H CB  1 
ATOM   1588 C  CG  . LYS   A 1 216 ? 16.18900  5.55500  -1.89500  1.000 53.96977  ? 216 LYS   H CG  1 
ATOM   1589 C  CD  . LYS   A 1 216 ? 16.39700  4.14000  -2.41900  1.000 54.86356  ? 216 LYS   H CD  1 
ATOM   1590 C  CE  . LYS   A 1 216 ? 16.16800  3.10200  -1.32700  1.000 58.46034  ? 216 LYS   H CE  1 
ATOM   1591 N  NZ  . LYS   A 1 216 ? 16.34400  1.70800  -1.82900  1.000 65.59062  ? 216 LYS   H NZ  1 
ATOM   1592 N  N   . VAL   A 1 217 ? 16.82100  7.60500  2.08100   1.000 51.16142  ? 217 VAL   H N   1 
ATOM   1593 C  CA  . VAL   A 1 217 ? 17.23700  7.76700  3.46800   1.000 51.59797  ? 217 VAL   H CA  1 
ATOM   1594 C  C   . VAL   A 1 217 ? 16.50900  6.73900  4.32200   1.000 48.97531  ? 217 VAL   H C   1 
ATOM   1595 O  O   . VAL   A 1 217 ? 15.28600  6.59000  4.21600   1.000 52.06923  ? 217 VAL   H O   1 
ATOM   1596 C  CB  . VAL   A 1 217 ? 16.95600  9.19100  3.98400   1.000 48.05418  ? 217 VAL   H CB  1 
ATOM   1597 C  CG1 . VAL   A 1 217 ? 17.41700  9.33100  5.42300   1.000 45.46412  ? 217 VAL   H CG1 1 
ATOM   1598 C  CG2 . VAL   A 1 217 ? 17.64700  10.21900 3.10200   1.000 47.87557  ? 217 VAL   H CG2 1 
ATOM   1599 N  N   . ASP   A 1 218 ? 17.25600  6.03500  5.16400   1.000 43.48175  ? 218 ASP   H N   1 
ATOM   1600 C  CA  . ASP   A 1 218 ? 16.69300  5.09900  6.13200   1.000 48.74334  ? 218 ASP   H CA  1 
ATOM   1601 C  C   . ASP   A 1 218 ? 17.15200  5.54100  7.51700   1.000 56.17810  ? 218 ASP   H C   1 
ATOM   1602 O  O   . ASP   A 1 218 ? 18.26500  5.21700  7.94300   1.000 63.66592  ? 218 ASP   H O   1 
ATOM   1603 C  CB  . ASP   A 1 218 ? 17.11300  3.66600  5.83000   1.000 50.43476  ? 218 ASP   H CB  1 
ATOM   1604 C  CG  . ASP   A 1 218 ? 16.32300  3.05700  4.69000   1.000 59.97696  ? 218 ASP   H CG  1 
ATOM   1605 O  OD1 . ASP   A 1 218 ? 16.35300  1.81600  4.54500   1.000 63.14914  ? 218 ASP   H OD1 1 
ATOM   1606 O  OD2 . ASP   A 1 218 ? 15.67400  3.81500  3.94100   1.000 58.79081  ? 218 ASP   H OD2 1 
ATOM   1607 N  N   . LYS   A 1 219 ? 16.29300  6.28100  8.21200   1.000 53.25519  ? 219 LYS   H N   1 
ATOM   1608 C  CA  . LYS   A 1 219 ? 16.58100  6.74000  9.56300   1.000 52.03529  ? 219 LYS   H CA  1 
ATOM   1609 C  C   . LYS   A 1 219 ? 15.98000  5.77600  10.57600  1.000 54.74595  ? 219 LYS   H C   1 
ATOM   1610 O  O   . LYS   A 1 219 ? 14.79800  5.42600  10.48800  1.000 52.96878  ? 219 LYS   H O   1 
ATOM   1611 C  CB  . LYS   A 1 219 ? 16.03200  8.14900  9.79100   1.000 52.08410  ? 219 LYS   H CB  1 
ATOM   1612 C  CG  . LYS   A 1 219 ? 16.57600  8.83300  11.04200  1.000 49.14968  ? 219 LYS   H CG  1 
ATOM   1613 C  CD  . LYS   A 1 219 ? 17.96400  9.41400  10.81000  1.000 54.06653  ? 219 LYS   H CD  1 
ATOM   1614 C  CE  . LYS   A 1 219 ? 18.58100  9.90400  12.11100  1.000 58.27036  ? 219 LYS   H CE  1 
ATOM   1615 N  NZ  . LYS   A 1 219 ? 19.96800  10.40500 11.90800  1.000 62.84125  ? 219 LYS   H NZ  1 
ATOM   1616 N  N   . ARG   A 1 220 ? 16.79600  5.34900  11.53300  1.000 57.61974  ? 220 ARG   H N   1 
ATOM   1617 C  CA  . ARG   A 1 220 ? 16.32900  4.52800  12.64000  1.000 53.58416  ? 220 ARG   H CA  1 
ATOM   1618 C  C   . ARG   A 1 220 ? 15.96000  5.43700  13.80600  1.000 52.19504  ? 220 ARG   H C   1 
ATOM   1619 O  O   . ARG   A 1 220 ? 16.74500  6.30900  14.19300  1.000 56.64649  ? 220 ARG   H O   1 
ATOM   1620 C  CB  . ARG   A 1 220 ? 17.40400  3.51900  13.04800  1.000 56.89412  ? 220 ARG   H CB  1 
ATOM   1621 C  CG  . ARG   A 1 220 ? 17.24000  2.91300  14.43300  1.000 54.10638  ? 220 ARG   H CG  1 
ATOM   1622 C  CD  . ARG   A 1 220 ? 17.67400  1.45100  14.42600  1.000 60.40379  ? 220 ARG   H CD  1 
ATOM   1623 N  NE  . ARG   A 1 220 ? 17.76000  0.85700  15.75900  1.000 69.71582  ? 220 ARG   H NE  1 
ATOM   1624 C  CZ  . ARG   A 1 220 ? 16.73500  0.68100  16.58800  1.000 72.14899  ? 220 ARG   H CZ  1 
ATOM   1625 N  NH1 . ARG   A 1 220 ? 15.50800  1.04600  16.24000  1.000 64.97938  ? 220 ARG   H NH1 1 
ATOM   1626 N  NH2 . ARG   A 1 220 ? 16.94000  0.12900  17.77500  1.000 62.68313  ? 220 ARG   H NH2 1 
ATOM   1627 N  N   . VAL   A 1 221 ? 14.76200  5.24100  14.35100  1.000 53.41455  ? 221 VAL   H N   1 
ATOM   1628 C  CA  . VAL   A 1 221 ? 14.21700  6.10100  15.39700  1.000 50.89702  ? 221 VAL   H CA  1 
ATOM   1629 C  C   . VAL   A 1 221 ? 14.25300  5.34000  16.71400  1.000 50.06842  ? 221 VAL   H C   1 
ATOM   1630 O  O   . VAL   A 1 221 ? 13.61800  4.28700  16.85300  1.000 55.46523  ? 221 VAL   H O   1 
ATOM   1631 C  CB  . VAL   A 1 221 ? 12.79000  6.56200  15.06500  1.000 45.28002  ? 221 VAL   H CB  1 
ATOM   1632 C  CG1 . VAL   A 1 221 ? 12.35600  7.66400  16.01500  1.000 46.96096  ? 221 VAL   H CG1 1 
ATOM   1633 C  CG2 . VAL   A 1 221 ? 12.71200  7.03300  13.62000  1.000 42.63847  ? 221 VAL   H CG2 1 
ATOM   1634 N  N   . GLU   A 1 222 ? 14.98300  5.88100  17.68000  1.000 48.24251  ? 222 GLU   H N   1 
ATOM   1635 C  CA  . GLU   A 1 222 ? 15.17400  5.29700  18.99500  1.000 54.75466  ? 222 GLU   H CA  1 
ATOM   1636 C  C   . GLU   A 1 222 ? 14.75700  6.28800  20.07500  1.000 54.06159  ? 222 GLU   H C   1 
ATOM   1637 O  O   . GLU   A 1 222 ? 14.63300  7.49000  19.81200  1.000 52.09593  ? 222 GLU   H O   1 
ATOM   1638 C  CB  . GLU   A 1 222 ? 16.64200  4.89400  19.20400  1.000 60.34708  ? 222 GLU   H CB  1 
ATOM   1639 C  CG  . GLU   A 1 222 ? 17.16600  3.89400  18.18900  1.000 64.98956  ? 222 GLU   H CG  1 
ATOM   1640 C  CD  . GLU   A 1 222 ? 18.67000  3.72700  18.26700  1.000 76.14403  ? 222 GLU   H CD  1 
ATOM   1641 O  OE1 . GLU   A 1 222 ? 19.38100  4.35200  17.45000  1.000 70.44661  ? 222 GLU   H OE1 1 
ATOM   1642 O  OE2 . GLU   A 1 222 ? 19.14200  2.97300  19.14300  1.000 78.64612  ? 222 GLU   H OE2 1 
ATOM   1643 N  N   . PRO   A 1 223 ? 14.51500  5.81700  21.29800  1.000 57.06559  ? 223 PRO   H N   1 
ATOM   1644 C  CA  . PRO   A 1 223 ? 14.25100  6.74800  22.40000  1.000 58.84103  ? 223 PRO   H CA  1 
ATOM   1645 C  C   . PRO   A 1 223 ? 15.48800  7.56400  22.74300  1.000 62.78651  ? 223 PRO   H C   1 
ATOM   1646 O  O   . PRO   A 1 223 ? 16.60100  7.03800  22.83100  1.000 56.68503  ? 223 PRO   H O   1 
ATOM   1647 C  CB  . PRO   A 1 223 ? 13.84900  5.82800  23.55900  1.000 52.98596  ? 223 PRO   H CB  1 
ATOM   1648 C  CG  . PRO   A 1 223 ? 13.39800  4.56200  22.90300  1.000 52.95004  ? 223 PRO   H CG  1 
ATOM   1649 C  CD  . PRO   A 1 223 ? 14.27100  4.41900  21.69300  1.000 51.92231  ? 223 PRO   H CD  1 
ATOM   1650 N  N   . LYS   A 1 224 ? 15.28000  8.86200  22.94000  1.000 66.90948  ? 224 LYS   H N   1 
ATOM   1651 C  CA  . LYS   A 1 224 ? 16.37000  9.76900  23.28100  1.000 62.45456  ? 224 LYS   H CA  1 
ATOM   1652 C  C   . LYS   A 1 224 ? 16.59800  9.79000  24.79000  1.000 57.34739  ? 224 LYS   H C   1 
ATOM   1653 O  O   . LYS   A 1 224 ? 17.52100  9.15300  25.29900  1.000 51.29866  ? 224 LYS   H O   1 
ATOM   1654 C  CB  . LYS   A 1 224 ? 16.07700  11.18200 22.76700  1.000 54.64620  ? 224 LYS   H CB  1 
ATOM   1655 N  N   . GLU   B 2 1   ? -17.04600 30.36700 -23.27700 1.000 59.21034  ? 1   GLU   L N   1 
ATOM   1656 C  CA  . GLU   B 2 1   ? -16.80400 29.48800 -22.13900 1.000 59.75881  ? 1   GLU   L CA  1 
ATOM   1657 C  C   . GLU   B 2 1   ? -18.01300 29.44900 -21.20800 1.000 60.60544  ? 1   GLU   L C   1 
ATOM   1658 O  O   . GLU   B 2 1   ? -18.74000 30.43700 -21.07900 1.000 57.31510  ? 1   GLU   L O   1 
ATOM   1659 C  CB  . GLU   B 2 1   ? -15.55700 29.94200 -21.37200 1.000 58.69218  ? 1   GLU   L CB  1 
ATOM   1660 C  CG  . GLU   B 2 1   ? -15.25000 29.14400 -20.11800 1.000 57.56656  ? 1   GLU   L CG  1 
ATOM   1661 C  CD  . GLU   B 2 1   ? -14.27500 29.85300 -19.20300 1.000 60.72558  ? 1   GLU   L CD  1 
ATOM   1662 O  OE1 . GLU   B 2 1   ? -13.17100 30.20400 -19.66700 1.000 58.04495  ? 1   GLU   L OE1 1 
ATOM   1663 O  OE2 . GLU   B 2 1   ? -14.61600 30.06200 -18.02000 1.000 60.12222  ? 1   GLU   L OE2 1 
ATOM   1664 N  N   . ILE   B 2 2   ? -18.22000 28.29600 -20.57100 1.000 46.81337  ? 2   ILE   L N   1 
ATOM   1665 C  CA  . ILE   B 2 2   ? -19.30600 28.07700 -19.62400 1.000 46.79808  ? 2   ILE   L CA  1 
ATOM   1666 C  C   . ILE   B 2 2   ? -18.70800 27.89300 -18.23600 1.000 52.25379  ? 2   ILE   L C   1 
ATOM   1667 O  O   . ILE   B 2 2   ? -17.66600 27.24500 -18.07800 1.000 48.10295  ? 2   ILE   L O   1 
ATOM   1668 C  CB  . ILE   B 2 2   ? -20.15800 26.85400 -20.02200 1.000 37.60730  ? 2   ILE   L CB  1 
ATOM   1669 C  CG1 . ILE   B 2 2   ? -20.72200 27.03100 -21.43200 1.000 44.92152  ? 2   ILE   L CG1 1 
ATOM   1670 C  CG2 . ILE   B 2 2   ? -21.28900 26.62800 -19.02600 1.000 39.99567  ? 2   ILE   L CG2 1 
ATOM   1671 C  CD1 . ILE   B 2 2   ? -21.46300 25.81800 -21.94800 1.000 45.11332  ? 2   ILE   L CD1 1 
ATOM   1672 N  N   . VAL   B 2 3   ? -19.36300 28.46900 -17.23100 1.000 50.87528  ? 3   VAL   L N   1 
ATOM   1673 C  CA  . VAL   B 2 3   ? -18.94800 28.33900 -15.83900 1.000 38.45039  ? 3   VAL   L CA  1 
ATOM   1674 C  C   . VAL   B 2 3   ? -19.87300 27.34400 -15.15500 1.000 36.01586  ? 3   VAL   L C   1 
ATOM   1675 O  O   . VAL   B 2 3   ? -21.09900 27.41900 -15.30400 1.000 37.41563  ? 3   VAL   L O   1 
ATOM   1676 C  CB  . VAL   B 2 3   ? -18.96800 29.70000 -15.11900 1.000 43.67628  ? 3   VAL   L CB  1 
ATOM   1677 C  CG1 . VAL   B 2 3   ? -18.89800 29.51200 -13.60600 1.000 39.65390  ? 3   VAL   L CG1 1 
ATOM   1678 C  CG2 . VAL   B 2 3   ? -17.82000 30.57500 -15.60200 1.000 41.29572  ? 3   VAL   L CG2 1 
ATOM   1679 N  N   . LEU   B 2 4   ? -19.28900 26.40300 -14.41800 1.000 36.30610  ? 4   LEU   L N   1 
ATOM   1680 C  CA  . LEU   B 2 4   ? -20.03800 25.40700 -13.66300 1.000 34.23226  ? 4   LEU   L CA  1 
ATOM   1681 C  C   . LEU   B 2 4   ? -19.88100 25.69700 -12.17600 1.000 33.03046  ? 4   LEU   L C   1 
ATOM   1682 O  O   . LEU   B 2 4   ? -18.76700 25.63400 -11.64300 1.000 31.04309  ? 4   LEU   L O   1 
ATOM   1683 C  CB  . LEU   B 2 4   ? -19.55500 23.99400 -13.98700 1.000 38.54272  ? 4   LEU   L CB  1 
ATOM   1684 C  CG  . LEU   B 2 4   ? -19.87800 23.45900 -15.38300 1.000 36.79263  ? 4   LEU   L CG  1 
ATOM   1685 C  CD1 . LEU   B 2 4   ? -19.22200 22.10700 -15.60100 1.000 34.69397  ? 4   LEU   L CD1 1 
ATOM   1686 C  CD2 . LEU   B 2 4   ? -21.37700 23.35900 -15.57500 1.000 40.57105  ? 4   LEU   L CD2 1 
ATOM   1687 N  N   . THR   B 2 5   ? -20.99000 26.01100 -11.51300 1.000 32.26795  ? 5   THR   L N   1 
ATOM   1688 C  CA  . THR   B 2 5   ? -20.99600 26.30700 -10.08600 1.000 36.61633  ? 5   THR   L CA  1 
ATOM   1689 C  C   . THR   B 2 5   ? -21.55700 25.10900 -9.33000  1.000 33.64998  ? 5   THR   L C   1 
ATOM   1690 O  O   . THR   B 2 5   ? -22.69300 24.68900 -9.57700  1.000 33.24286  ? 5   THR   L O   1 
ATOM   1691 C  CB  . THR   B 2 5   ? -21.81800 27.56000 -9.78400  1.000 35.64686  ? 5   THR   L CB  1 
ATOM   1692 O  OG1 . THR   B 2 5   ? -21.56900 28.55400 -10.78600 1.000 37.27354  ? 5   THR   L OG1 1 
ATOM   1693 C  CG2 . THR   B 2 5   ? -21.44600 28.12100 -8.41900  1.000 26.38355  ? 5   THR   L CG2 1 
ATOM   1694 N  N   . GLN   B 2 6   ? -20.76300 24.56600 -8.41400  1.000 30.80300  ? 6   GLN   L N   1 
ATOM   1695 C  CA  . GLN   B 2 6   ? -21.17400 23.43100 -7.60200  1.000 36.90053  ? 6   GLN   L CA  1 
ATOM   1696 C  C   . GLN   B 2 6   ? -21.52600 23.89100 -6.19500  1.000 36.29906  ? 6   GLN   L C   1 
ATOM   1697 O  O   . GLN   B 2 6   ? -20.82600 24.72100 -5.60600  1.000 44.94544  ? 6   GLN   L O   1 
ATOM   1698 C  CB  . GLN   B 2 6   ? -20.07400 22.37100 -7.54700  1.000 38.77131  ? 6   GLN   L CB  1 
ATOM   1699 C  CG  . GLN   B 2 6   ? -19.78800 21.71900 -8.88500  1.000 32.88303  ? 6   GLN   L CG  1 
ATOM   1700 C  CD  . GLN   B 2 6   ? -18.93300 20.47600 -8.75700  1.000 37.67462  ? 6   GLN   L CD  1 
ATOM   1701 O  OE1 . GLN   B 2 6   ? -17.91000 20.34200 -9.42800  1.000 41.72363  ? 6   GLN   L OE1 1 
ATOM   1702 N  NE2 . GLN   B 2 6   ? -19.34900 19.55800 -7.89200  1.000 34.73514  ? 6   GLN   L NE2 1 
ATOM   1703 N  N   . SER   B 2 7   ? -22.61900 23.34600 -5.66200  1.000 36.57670  ? 7   SER   L N   1 
ATOM   1704 C  CA  . SER   B 2 7   ? -23.07400 23.63700 -4.31400  1.000 35.12792  ? 7   SER   L CA  1 
ATOM   1705 C  C   . SER   B 2 7   ? -23.50000 22.33800 -3.64300  1.000 38.75551  ? 7   SER   L C   1 
ATOM   1706 O  O   . SER   B 2 7   ? -24.08900 21.46500 -4.29900  1.000 37.93851  ? 7   SER   L O   1 
ATOM   1707 C  CB  . SER   B 2 7   ? -24.24400 24.63200 -4.30900  1.000 36.29712  ? 7   SER   L CB  1 
ATOM   1708 O  OG  . SER   B 2 7   ? -25.12300 24.40200 -5.39700  1.000 50.70403  ? 7   SER   L OG  1 
ATOM   1709 N  N   . PRO   B 2 8   ? -23.20600 22.17100 -2.34500  1.000 35.06853  ? 8   PRO   L N   1 
ATOM   1710 C  CA  . PRO   B 2 8   ? -22.44000 23.13900 -1.55600  1.000 41.70450  ? 8   PRO   L CA  1 
ATOM   1711 C  C   . PRO   B 2 8   ? -20.93600 22.95300 -1.71900  1.000 38.79569  ? 8   PRO   L C   1 
ATOM   1712 O  O   . PRO   B 2 8   ? -20.50700 22.06300 -2.45200  1.000 41.43106  ? 8   PRO   L O   1 
ATOM   1713 C  CB  . PRO   B 2 8   ? -22.87300 22.83400 -0.12300  1.000 39.87735  ? 8   PRO   L CB  1 
ATOM   1714 C  CG  . PRO   B 2 8   ? -23.17200 21.37200 -0.14000  1.000 38.03794  ? 8   PRO   L CG  1 
ATOM   1715 C  CD  . PRO   B 2 8   ? -23.70100 21.05500 -1.51900  1.000 34.98223  ? 8   PRO   L CD  1 
ATOM   1716 N  N   . GLY   B 2 9   ? -20.14600 23.79300 -1.05100  1.000 39.65099  ? 9   GLY   L N   1 
ATOM   1717 C  CA  . GLY   B 2 9   ? -18.70700 23.59200 -1.06200  1.000 33.38144  ? 9   GLY   L CA  1 
ATOM   1718 C  C   . GLY   B 2 9   ? -18.30300 22.33800 -0.31000  1.000 39.76633  ? 9   GLY   L C   1 
ATOM   1719 O  O   . GLY   B 2 9   ? -17.50200 21.53600 -0.79800  1.000 42.90020  ? 9   GLY   L O   1 
ATOM   1720 N  N   . THR   B 2 10  ? -18.86100 22.14700 0.88400   1.000 43.64876  ? 10  THR   L N   1 
ATOM   1721 C  CA  . THR   B 2 10  ? -18.59700 20.97400 1.70300   1.000 37.57866  ? 10  THR   L CA  1 
ATOM   1722 C  C   . THR   B 2 10  ? -19.91400 20.34400 2.13300   1.000 38.00286  ? 10  THR   L C   1 
ATOM   1723 O  O   . THR   B 2 10  ? -20.92500 21.03100 2.30300   1.000 37.65947  ? 10  THR   L O   1 
ATOM   1724 C  CB  . THR   B 2 10  ? -17.76500 21.32400 2.94500   1.000 36.40652  ? 10  THR   L CB  1 
ATOM   1725 O  OG1 . THR   B 2 10  ? -16.83700 22.36400 2.62000   1.000 49.44221  ? 10  THR   L OG1 1 
ATOM   1726 C  CG2 . THR   B 2 10  ? -16.99600 20.10700 3.43700   1.000 43.94549  ? 10  THR   L CG2 1 
ATOM   1727 N  N   . LEU   B 2 11  ? -19.88900 19.02500 2.31000   1.000 42.23679  ? 11  LEU   L N   1 
ATOM   1728 C  CA  . LEU   B 2 11  ? -21.05900 18.27100 2.74500   1.000 38.69790  ? 11  LEU   L CA  1 
ATOM   1729 C  C   . LEU   B 2 11  ? -20.60700 17.21200 3.73800   1.000 40.06850  ? 11  LEU   L C   1 
ATOM   1730 O  O   . LEU   B 2 11  ? -19.85700 16.30100 3.37600   1.000 41.74887  ? 11  LEU   L O   1 
ATOM   1731 C  CB  . LEU   B 2 11  ? -21.77600 17.62600 1.55400   1.000 36.87062  ? 11  LEU   L CB  1 
ATOM   1732 C  CG  . LEU   B 2 11  ? -23.16600 17.03900 1.81500   1.000 38.10344  ? 11  LEU   L CG  1 
ATOM   1733 C  CD1 . LEU   B 2 11  ? -24.09300 18.08100 2.42400   1.000 33.94094  ? 11  LEU   L CD1 1 
ATOM   1734 C  CD2 . LEU   B 2 11  ? -23.76700 16.46300 0.54200   1.000 47.72815  ? 11  LEU   L CD2 1 
ATOM   1735 N  N   . SER   B 2 12  ? -21.05500 17.33600 4.98400   1.000 40.72106  ? 12  SER   L N   1 
ATOM   1736 C  CA  . SER   B 2 12  ? -20.70900 16.40100 6.04800   1.000 38.96885  ? 12  SER   L CA  1 
ATOM   1737 C  C   . SER   B 2 12  ? -21.94700 15.59200 6.40800   1.000 43.00877  ? 12  SER   L C   1 
ATOM   1738 O  O   . SER   B 2 12  ? -22.95100 16.15500 6.85900   1.000 41.18740  ? 12  SER   L O   1 
ATOM   1739 C  CB  . SER   B 2 12  ? -20.17100 17.14100 7.27200   1.000 39.27460  ? 12  SER   L CB  1 
ATOM   1740 O  OG  . SER   B 2 12  ? -19.63700 16.23300 8.22000   1.000 49.45790  ? 12  SER   L OG  1 
ATOM   1741 N  N   . LEU   B 2 13  ? -21.87800 14.27800 6.20100   1.000 43.77978  ? 13  LEU   L N   1 
ATOM   1742 C  CA  . LEU   B 2 13  ? -23.02300 13.40500 6.40400   1.000 43.98278  ? 13  LEU   L CA  1 
ATOM   1743 C  C   . LEU   B 2 13  ? -22.57900 12.10700 7.06000   1.000 46.01591  ? 13  LEU   L C   1 
ATOM   1744 O  O   . LEU   B 2 13  ? -21.45700 11.63600 6.85400   1.000 47.69848  ? 13  LEU   L O   1 
ATOM   1745 C  CB  . LEU   B 2 13  ? -23.73900 13.09000 5.08400   1.000 45.85861  ? 13  LEU   L CB  1 
ATOM   1746 C  CG  . LEU   B 2 13  ? -24.05800 14.26700 4.16500   1.000 40.78702  ? 13  LEU   L CG  1 
ATOM   1747 C  CD1 . LEU   B 2 13  ? -24.35000 13.76000 2.77900   1.000 47.30077  ? 13  LEU   L CD1 1 
ATOM   1748 C  CD2 . LEU   B 2 13  ? -25.23000 15.07600 4.70000   1.000 39.23162  ? 13  LEU   L CD2 1 
ATOM   1749 N  N   . SER   B 2 14  ? -23.48400 11.53400 7.84800   1.000 50.32203  ? 14  SER   L N   1 
ATOM   1750 C  CA  . SER   B 2 14  ? -23.27900 10.25100 8.49500   1.000 48.52744  ? 14  SER   L CA  1 
ATOM   1751 C  C   . SER   B 2 14  ? -23.43000 9.11600  7.48500   1.000 46.01396  ? 14  SER   L C   1 
ATOM   1752 O  O   . SER   B 2 14  ? -24.05000 9.28900  6.43200   1.000 45.17957  ? 14  SER   L O   1 
ATOM   1753 C  CB  . SER   B 2 14  ? -24.28200 10.08400 9.63400   1.000 51.54313  ? 14  SER   L CB  1 
ATOM   1754 O  OG  . SER   B 2 14  ? -23.76100 9.28100  10.67900  1.000 57.58025  ? 14  SER   L OG  1 
ATOM   1755 N  N   . PRO   B 2 15  ? -22.84800 7.94900  7.76600   1.000 47.95601  ? 15  PRO   L N   1 
ATOM   1756 C  CA  . PRO   B 2 15  ? -23.07000 6.79300  6.88900   1.000 39.56750  ? 15  PRO   L CA  1 
ATOM   1757 C  C   . PRO   B 2 15  ? -24.54400 6.41800  6.83100   1.000 40.78008  ? 15  PRO   L C   1 
ATOM   1758 O  O   . PRO   B 2 15  ? -25.23900 6.39400  7.84800   1.000 45.96056  ? 15  PRO   L O   1 
ATOM   1759 C  CB  . PRO   B 2 15  ? -22.23300 5.68700  7.54200   1.000 36.02875  ? 15  PRO   L CB  1 
ATOM   1760 C  CG  . PRO   B 2 15  ? -21.17100 6.41400  8.28800   1.000 43.51464  ? 15  PRO   L CG  1 
ATOM   1761 C  CD  . PRO   B 2 15  ? -21.80900 7.68300  8.77700   1.000 45.05428  ? 15  PRO   L CD  1 
ATOM   1762 N  N   . GLY   B 2 16  ? -25.01800 6.12000  5.62100   1.000 43.18773  ? 16  GLY   L N   1 
ATOM   1763 C  CA  . GLY   B 2 16  ? -26.39500 5.75900  5.38100   1.000 47.72216  ? 16  GLY   L CA  1 
ATOM   1764 C  C   . GLY   B 2 16  ? -27.25500 6.90200  4.88100   1.000 52.31059  ? 16  GLY   L C   1 
ATOM   1765 O  O   . GLY   B 2 16  ? -28.20300 6.66600  4.12200   1.000 51.75475  ? 16  GLY   L O   1 
ATOM   1766 N  N   . GLU   B 2 17  ? -26.95000 8.13100  5.29200   1.000 51.30793  ? 17  GLU   L N   1 
ATOM   1767 C  CA  . GLU   B 2 17  ? -27.67800 9.28700  4.79600   1.000 50.47812  ? 17  GLU   L CA  1 
ATOM   1768 C  C   . GLU   B 2 17  ? -27.44300 9.45200  3.29800   1.000 55.27988  ? 17  GLU   L C   1 
ATOM   1769 O  O   . GLU   B 2 17  ? -26.51100 8.88700  2.72000   1.000 56.48342  ? 17  GLU   L O   1 
ATOM   1770 C  CB  . GLU   B 2 17  ? -27.25000 10.55300 5.54200   1.000 51.68541  ? 17  GLU   L CB  1 
ATOM   1771 C  CG  . GLU   B 2 17  ? -26.98500 10.35200 7.02800   1.000 51.91174  ? 17  GLU   L CG  1 
ATOM   1772 C  CD  . GLU   B 2 17  ? -27.33300 11.57500 7.86400   1.000 59.07359  ? 17  GLU   L CD  1 
ATOM   1773 O  OE1 . GLU   B 2 17  ? -28.47800 11.66100 8.35700   1.000 59.03988  ? 17  GLU   L OE1 1 
ATOM   1774 O  OE2 . GLU   B 2 17  ? -26.45800 12.45200 8.02900   1.000 53.72281  ? 17  GLU   L OE2 1 
ATOM   1775 N  N   . ARG   B 2 18  ? -28.30600 10.23700 2.66400   1.000 56.33000  ? 18  ARG   L N   1 
ATOM   1776 C  CA  . ARG   B 2 18  ? -28.24700 10.44600 1.22500   1.000 53.23274  ? 18  ARG   L CA  1 
ATOM   1777 C  C   . ARG   B 2 18  ? -27.63200 11.80400 0.91400   1.000 50.39542  ? 18  ARG   L C   1 
ATOM   1778 O  O   . ARG   B 2 18  ? -28.08100 12.83100 1.43400   1.000 48.95660  ? 18  ARG   L O   1 
ATOM   1779 C  CB  . ARG   B 2 18  ? -29.63800 10.34200 0.59900   1.000 53.57858  ? 18  ARG   L CB  1 
ATOM   1780 C  CG  . ARG   B 2 18  ? -29.66700 10.67300 -0.88700  1.000 57.15589  ? 18  ARG   L CG  1 
ATOM   1781 C  CD  . ARG   B 2 18  ? -31.08800 10.68600 -1.42800  1.000 63.83280  ? 18  ARG   L CD  1 
ATOM   1782 N  NE  . ARG   B 2 18  ? -31.87700 9.56000  -0.93600  1.000 69.12681  ? 18  ARG   L NE  1 
ATOM   1783 C  CZ  . ARG   B 2 18  ? -32.52100 8.70600  -1.72500  1.000 71.69519  ? 18  ARG   L CZ  1 
ATOM   1784 N  NH1 . ARG   B 2 18  ? -32.46600 8.85300  -3.04100  1.000 73.34038  ? 18  ARG   L NH1 1 
ATOM   1785 N  NH2 . ARG   B 2 18  ? -33.21900 7.70600  -1.20200  1.000 64.51198  ? 18  ARG   L NH2 1 
ATOM   1786 N  N   . ALA   B 2 19  ? -26.61100 11.80000 0.05900   1.000 53.70597  ? 19  ALA   L N   1 
ATOM   1787 C  CA  . ALA   B 2 19  ? -25.95600 13.01900 -0.39000  1.000 47.39977  ? 19  ALA   L CA  1 
ATOM   1788 C  C   . ALA   B 2 19  ? -26.58400 13.51000 -1.68700  1.000 46.96767  ? 19  ALA   L C   1 
ATOM   1789 O  O   . ALA   B 2 19  ? -26.87300 12.72000 -2.59000  1.000 49.69726  ? 19  ALA   L O   1 
ATOM   1790 C  CB  . ALA   B 2 19  ? -24.46000 12.78300 -0.59800  1.000 42.19150  ? 19  ALA   L CB  1 
ATOM   1791 N  N   . THR   B 2 20  ? -26.79400 14.82100 -1.77400  1.000 43.77509  ? 20  THR   L N   1 
ATOM   1792 C  CA  . THR   B 2 20  ? -27.33000 15.45500 -2.97400  1.000 44.20681  ? 20  THR   L CA  1 
ATOM   1793 C  C   . THR   B 2 20  ? -26.38400 16.57700 -3.37500  1.000 40.79380  ? 20  THR   L C   1 
ATOM   1794 O  O   . THR   B 2 20  ? -26.25800 17.57500 -2.65700  1.000 38.67227  ? 20  THR   L O   1 
ATOM   1795 C  CB  . THR   B 2 20  ? -28.74700 15.98500 -2.74400  1.000 46.73477  ? 20  THR   L CB  1 
ATOM   1796 O  OG1 . THR   B 2 20  ? -29.65700 14.88400 -2.62900  1.000 45.76669  ? 20  THR   L OG1 1 
ATOM   1797 C  CG2 . THR   B 2 20  ? -29.17900 16.87000 -3.90500  1.000 40.55221  ? 20  THR   L CG2 1 
ATOM   1798 N  N   . LEU   B 2 21  ? -25.71500 16.40900 -4.51100  1.000 39.08663  ? 21  LEU   L N   1 
ATOM   1799 C  CA  . LEU   B 2 21  ? -24.77100 17.38800 -5.02800  1.000 37.54908  ? 21  LEU   L CA  1 
ATOM   1800 C  C   . LEU   B 2 21  ? -25.35800 18.06200 -6.26200  1.000 37.25688  ? 21  LEU   L C   1 
ATOM   1801 O  O   . LEU   B 2 21  ? -26.09700 17.44400 -7.03300  1.000 36.35596  ? 21  LEU   L O   1 
ATOM   1802 C  CB  . LEU   B 2 21  ? -23.42800 16.73300 -5.37000  1.000 36.40032  ? 21  LEU   L CB  1 
ATOM   1803 C  CG  . LEU   B 2 21  ? -22.78000 15.83000 -4.31400  1.000 35.81477  ? 21  LEU   L CG  1 
ATOM   1804 C  CD1 . LEU   B 2 21  ? -21.30600 15.64600 -4.61000  1.000 42.06475  ? 21  LEU   L CD1 1 
ATOM   1805 C  CD2 . LEU   B 2 21  ? -22.95600 16.38800 -2.91500  1.000 42.49272  ? 21  LEU   L CD2 1 
ATOM   1806 N  N   . SER   B 2 22  ? -25.02800 19.34000 -6.44300  1.000 41.75397  ? 22  SER   L N   1 
ATOM   1807 C  CA  . SER   B 2 22  ? -25.64100 20.15800 -7.47900  1.000 43.86382  ? 22  SER   L CA  1 
ATOM   1808 C  C   . SER   B 2 22  ? -24.57500 20.81100 -8.34600  1.000 36.07868  ? 22  SER   L C   1 
ATOM   1809 O  O   . SER   B 2 22  ? -23.49900 21.17200 -7.86100  1.000 32.79206  ? 22  SER   L O   1 
ATOM   1810 C  CB  . SER   B 2 22  ? -26.54600 21.23600 -6.86900  1.000 47.24464  ? 22  SER   L CB  1 
ATOM   1811 O  OG  . SER   B 2 22  ? -27.10200 22.06600 -7.87300  1.000 53.47508  ? 22  SER   L OG  1 
ATOM   1812 N  N   . CYS   B 2 23  ? -24.88400 20.95800 -9.63200  1.000 38.75237  ? 23  CYS   L N   1 
ATOM   1813 C  CA  . CYS   B 2 23  ? -24.00200 21.62200 -10.58600 1.000 43.98342  ? 23  CYS   L CA  1 
ATOM   1814 C  C   . CYS   B 2 23  ? -24.86000 22.48800 -11.49300 1.000 35.61983  ? 23  CYS   L C   1 
ATOM   1815 O  O   . CYS   B 2 23  ? -25.75500 21.97800 -12.17400 1.000 40.78012  ? 23  CYS   L O   1 
ATOM   1816 C  CB  . CYS   B 2 23  ? -23.19600 20.60400 -11.40400 1.000 40.18281  ? 23  CYS   L CB  1 
ATOM   1817 S  SG  . CYS   B 2 23  ? -22.02900 21.31400 -12.60000 1.000 48.05426  ? 23  CYS   L SG  1 
ATOM   1818 N  N   . ARG   B 2 24  ? -24.59800 23.79200 -11.49200 1.000 36.23666  ? 24  ARG   L N   1 
ATOM   1819 C  CA  . ARG   B 2 24  ? -25.35800 24.75200 -12.28000 1.000 41.46895  ? 24  ARG   L CA  1 
ATOM   1820 C  C   . ARG   B 2 24  ? -24.44600 25.40500 -13.30700 1.000 36.09842  ? 24  ARG   L C   1 
ATOM   1821 O  O   . ARG   B 2 24  ? -23.40100 25.96100 -12.95300 1.000 34.35491  ? 24  ARG   L O   1 
ATOM   1822 C  CB  . ARG   B 2 24  ? -26.00300 25.81600 -11.38900 1.000 38.39318  ? 24  ARG   L CB  1 
ATOM   1823 C  CG  . ARG   B 2 24  ? -27.26500 25.34900 -10.68300 1.000 44.59375  ? 24  ARG   L CG  1 
ATOM   1824 C  CD  . ARG   B 2 24  ? -27.44500 26.05100 -9.34600  1.000 54.04759  ? 24  ARG   L CD  1 
ATOM   1825 N  NE  . ARG   B 2 24  ? -28.07800 25.18300 -8.35700  1.000 63.59244  ? 24  ARG   L NE  1 
ATOM   1826 C  CZ  . ARG   B 2 24  ? -29.14500 25.52100 -7.64200  1.000 63.40955  ? 24  ARG   L CZ  1 
ATOM   1827 N  NH1 . ARG   B 2 24  ? -29.65400 24.66800 -6.76300  1.000 48.59998  ? 24  ARG   L NH1 1 
ATOM   1828 N  NH2 . ARG   B 2 24  ? -29.70200 26.71400 -7.80300  1.000 60.81559  ? 24  ARG   L NH2 1 
ATOM   1829 N  N   . ALA   B 2 25  ? -24.84700 25.34100 -14.57200 1.000 34.41696  ? 25  ALA   L N   1 
ATOM   1830 C  CA  . ALA   B 2 25  ? -24.07200 25.91800 -15.65700 1.000 37.40450  ? 25  ALA   L CA  1 
ATOM   1831 C  C   . ALA   B 2 25  ? -24.53000 27.34200 -15.94800 1.000 36.71526  ? 25  ALA   L C   1 
ATOM   1832 O  O   . ALA   B 2 25  ? -25.70900 27.68000 -15.80500 1.000 35.52540  ? 25  ALA   L O   1 
ATOM   1833 C  CB  . ALA   B 2 25  ? -24.19400 25.06300 -16.91900 1.000 35.12753  ? 25  ALA   L CB  1 
ATOM   1834 N  N   . SER   B 2 26  ? -23.57600 28.18100 -16.35900 1.000 40.72035  ? 26  SER   L N   1 
ATOM   1835 C  CA  . SER   B 2 26  ? -23.90100 29.55300 -16.73000 1.000 39.72430  ? 26  SER   L CA  1 
ATOM   1836 C  C   . SER   B 2 26  ? -24.75500 29.61600 -17.98800 1.000 39.71047  ? 26  SER   L C   1 
ATOM   1837 O  O   . SER   B 2 26  ? -25.42400 30.62900 -18.22100 1.000 38.90788  ? 26  SER   L O   1 
ATOM   1838 C  CB  . SER   B 2 26  ? -22.62000 30.36300 -16.92700 1.000 37.16598  ? 26  SER   L CB  1 
ATOM   1839 O  OG  . SER   B 2 26  ? -21.77200 29.74900 -17.88200 1.000 42.69161  ? 26  SER   L OG  1 
ATOM   1840 N  N   . GLN   B 2 27  ? -24.73800 28.56400 -18.80400 1.000 43.60397  ? 27  GLN   L N   1 
ATOM   1841 C  CA  . GLN   B 2 27  ? -25.57700 28.46400 -19.99000 1.000 41.43755  ? 27  GLN   L CA  1 
ATOM   1842 C  C   . GLN   B 2 27  ? -26.18300 27.06500 -20.01900 1.000 41.35384  ? 27  GLN   L C   1 
ATOM   1843 O  O   . GLN   B 2 27  ? -26.08300 26.30100 -19.05500 1.000 46.18251  ? 27  GLN   L O   1 
ATOM   1844 C  CB  . GLN   B 2 27  ? -24.77000 28.76600 -21.26000 1.000 41.96914  ? 27  GLN   L CB  1 
ATOM   1845 C  CG  . GLN   B 2 27  ? -23.78800 29.92200 -21.12500 1.000 46.87549  ? 27  GLN   L CG  1 
ATOM   1846 C  CD  . GLN   B 2 27  ? -22.79100 29.98200 -22.26300 1.000 45.82883  ? 27  GLN   L CD  1 
ATOM   1847 O  OE1 . GLN   B 2 27  ? -23.02000 29.41700 -23.33100 1.000 41.82460  ? 27  GLN   L OE1 1 
ATOM   1848 N  NE2 . GLN   B 2 27  ? -21.67400 30.66900 -22.04000 1.000 56.67916  ? 27  GLN   L NE2 1 
ATOM   1849 N  N   . SER   B 2 28  ? -26.81700 26.72200 -21.13500 1.000 49.32616  ? 28  SER   L N   1 
ATOM   1850 C  CA  . SER   B 2 28  ? -27.33000 25.37300 -21.31900 1.000 49.13781  ? 28  SER   L CA  1 
ATOM   1851 C  C   . SER   B 2 28  ? -26.25400 24.47100 -21.91000 1.000 51.43221  ? 28  SER   L C   1 
ATOM   1852 O  O   . SER   B 2 28  ? -25.43800 24.89900 -22.73100 1.000 46.99412  ? 28  SER   L O   1 
ATOM   1853 C  CB  . SER   B 2 28  ? -28.56200 25.38200 -22.22200 1.000 44.12759  ? 28  SER   L CB  1 
ATOM   1854 O  OG  . SER   B 2 28  ? -29.39500 26.49100 -21.93800 1.000 51.65610  ? 28  SER   L OG  1 
ATOM   1855 N  N   . VAL   B 2 29  ? -26.25000 23.21400 -21.47500 1.000 45.99525  ? 29  VAL   L N   1 
ATOM   1856 C  CA  . VAL   B 2 29  ? -25.25500 22.23700 -21.90500 1.000 44.44136  ? 29  VAL   L CA  1 
ATOM   1857 C  C   . VAL   B 2 29  ? -25.88700 21.39000 -23.00300 1.000 47.87095  ? 29  VAL   L C   1 
ATOM   1858 O  O   . VAL   B 2 29  ? -26.87300 20.68200 -22.76700 1.000 51.40399  ? 29  VAL   L O   1 
ATOM   1859 C  CB  . VAL   B 2 29  ? -24.75900 21.37200 -20.73800 1.000 42.55013  ? 29  VAL   L CB  1 
ATOM   1860 C  CG1 . VAL   B 2 29  ? -23.60500 20.48900 -21.18100 1.000 44.96036  ? 29  VAL   L CG1 1 
ATOM   1861 C  CG2 . VAL   B 2 29  ? -24.34000 22.25200 -19.56700 1.000 39.13534  ? 29  VAL   L CG2 1 
ATOM   1862 N  N   . THR   B 2 30  ? -25.31100 21.46000 -24.20200 1.000 50.05959  ? 30  THR   L N   1 
ATOM   1863 C  CA  . THR   B 2 30  ? -25.89100 20.79100 -25.36000 1.000 51.98517  ? 30  THR   L CA  1 
ATOM   1864 C  C   . THR   B 2 30  ? -25.99900 19.29100 -25.12400 1.000 49.12947  ? 30  THR   L C   1 
ATOM   1865 O  O   . THR   B 2 30  ? -25.03500 18.64400 -24.70400 1.000 51.50792  ? 30  THR   L O   1 
ATOM   1866 C  CB  . THR   B 2 30  ? -25.05100 21.06300 -26.60800 1.000 57.21083  ? 30  THR   L CB  1 
ATOM   1867 O  OG1 . THR   B 2 30  ? -24.87600 22.47600 -26.77400 1.000 57.04791  ? 30  THR   L OG1 1 
ATOM   1868 C  CG2 . THR   B 2 30  ? -25.73100 20.48800 -27.84300 1.000 49.32286  ? 30  THR   L CG2 1 
ATOM   1869 N  N   . SER   B 2 31  ? -27.18800 18.74600 -25.39100 1.000 48.06331  ? 31  SER   L N   1 
ATOM   1870 C  CA  . SER   B 2 31  ? -27.47300 17.31500 -25.30800 1.000 47.32727  ? 31  SER   L CA  1 
ATOM   1871 C  C   . SER   B 2 31  ? -27.23300 16.74700 -23.91300 1.000 52.07616  ? 31  SER   L C   1 
ATOM   1872 O  O   . SER   B 2 31  ? -27.08300 15.53000 -23.75800 1.000 51.24234  ? 31  SER   L O   1 
ATOM   1873 C  CB  . SER   B 2 31  ? -26.65900 16.52600 -26.34000 1.000 46.30916  ? 31  SER   L CB  1 
ATOM   1874 O  OG  . SER   B 2 31  ? -26.67800 17.16900 -27.60200 1.000 43.89059  ? 31  SER   L OG  1 
ATOM   1875 N  N   . ASN   B 2 32  ? -27.19700 17.61100 -22.89600 1.000 51.55744  ? 32  ASN   L N   1 
ATOM   1876 C  CA  . ASN   B 2 32  ? -26.99200 17.19500 -21.50800 1.000 49.79449  ? 32  ASN   L CA  1 
ATOM   1877 C  C   . ASN   B 2 32  ? -25.68500 16.42200 -21.34500 1.000 46.10946  ? 32  ASN   L C   1 
ATOM   1878 O  O   . ASN   B 2 32  ? -25.62000 15.40900 -20.64500 1.000 48.68990  ? 32  ASN   L O   1 
ATOM   1879 C  CB  . ASN   B 2 32  ? -28.18000 16.37900 -20.99800 1.000 50.50696  ? 32  ASN   L CB  1 
ATOM   1880 C  CG  . ASN   B 2 32  ? -29.46100 17.18500 -20.95600 1.000 58.35518  ? 32  ASN   L CG  1 
ATOM   1881 O  OD1 . ASN   B 2 32  ? -29.43800 18.41500 -21.02700 1.000 54.05266  ? 32  ASN   L OD1 1 
ATOM   1882 N  ND2 . ASN   B 2 32  ? -30.58900 16.49500 -20.83600 1.000 55.33005  ? 32  ASN   L ND2 1 
ATOM   1883 N  N   . TYR   B 2 33  ? -24.63100 16.91000 -22.00100 1.000 39.01632  ? 33  TYR   L N   1 
ATOM   1884 C  CA  . TYR   B 2 33  ? -23.29200 16.33500 -21.87800 1.000 40.01474  ? 33  TYR   L CA  1 
ATOM   1885 C  C   . TYR   B 2 33  ? -22.68900 16.80000 -20.55400 1.000 40.84577  ? 33  TYR   L C   1 
ATOM   1886 O  O   . TYR   B 2 33  ? -21.89600 17.74100 -20.48700 1.000 36.52303  ? 33  TYR   L O   1 
ATOM   1887 C  CB  . TYR   B 2 33  ? -22.42200 16.74300 -23.06100 1.000 40.70486  ? 33  TYR   L CB  1 
ATOM   1888 C  CG  . TYR   B 2 33  ? -22.78800 16.08600 -24.37300 1.000 44.72796  ? 33  TYR   L CG  1 
ATOM   1889 C  CD1 . TYR   B 2 33  ? -23.50900 14.89900 -24.40700 1.000 45.28051  ? 33  TYR   L CD1 1 
ATOM   1890 C  CD2 . TYR   B 2 33  ? -22.40700 16.65400 -25.58100 1.000 41.68992  ? 33  TYR   L CD2 1 
ATOM   1891 C  CE1 . TYR   B 2 33  ? -23.84200 14.30000 -25.60800 1.000 41.23216  ? 33  TYR   L CE1 1 
ATOM   1892 C  CE2 . TYR   B 2 33  ? -22.73400 16.06400 -26.78500 1.000 44.34146  ? 33  TYR   L CE2 1 
ATOM   1893 C  CZ  . TYR   B 2 33  ? -23.45100 14.88700 -26.79400 1.000 45.28402  ? 33  TYR   L CZ  1 
ATOM   1894 O  OH  . TYR   B 2 33  ? -23.78100 14.29300 -27.99000 1.000 48.20391  ? 33  TYR   L OH  1 
ATOM   1895 N  N   . LEU   B 2 34  ? -23.07300 16.11600 -19.47600 1.000 44.63406  ? 34  LEU   L N   1 
ATOM   1896 C  CA  . LEU   B 2 34  ? -22.60000 16.43500 -18.13400 1.000 43.65003  ? 34  LEU   L CA  1 
ATOM   1897 C  C   . LEU   B 2 34  ? -22.11200 15.15800 -17.46900 1.000 37.92443  ? 34  LEU   L C   1 
ATOM   1898 O  O   . LEU   B 2 34  ? -22.78200 14.12300 -17.54100 1.000 43.30039  ? 34  LEU   L O   1 
ATOM   1899 C  CB  . LEU   B 2 34  ? -23.71200 17.08200 -17.29800 1.000 37.55061  ? 34  LEU   L CB  1 
ATOM   1900 C  CG  . LEU   B 2 34  ? -23.34500 17.77400 -15.98200 1.000 37.26578  ? 34  LEU   L CG  1 
ATOM   1901 C  CD1 . LEU   B 2 34  ? -22.84000 16.78600 -14.93600 1.000 45.79908  ? 34  LEU   L CD1 1 
ATOM   1902 C  CD2 . LEU   B 2 34  ? -22.32600 18.87100 -16.22300 1.000 31.67081  ? 34  LEU   L CD2 1 
ATOM   1903 N  N   . ALA   B 2 35  ? -20.95400 15.23100 -16.82000 1.000 33.64718  ? 35  ALA   L N   1 
ATOM   1904 C  CA  . ALA   B 2 35  ? -20.38800 14.08500 -16.12800 1.000 35.47785  ? 35  ALA   L CA  1 
ATOM   1905 C  C   . ALA   B 2 35  ? -20.12900 14.41100 -14.66500 1.000 32.91622  ? 35  ALA   L C   1 
ATOM   1906 O  O   . ALA   B 2 35  ? -20.06800 15.57600 -14.26400 1.000 36.29473  ? 35  ALA   L O   1 
ATOM   1907 C  CB  . ALA   B 2 35  ? -19.08300 13.62700 -16.77900 1.000 39.00069  ? 35  ALA   L CB  1 
ATOM   1908 N  N   . TRP   B 2 36  ? -19.97100 13.35600 -13.86900 1.000 38.19423  ? 36  TRP   L N   1 
ATOM   1909 C  CA  . TRP   B 2 36  ? -19.59200 13.47200 -12.46900 1.000 32.44044  ? 36  TRP   L CA  1 
ATOM   1910 C  C   . TRP   B 2 36  ? -18.39300 12.57600 -12.20900 1.000 32.65425  ? 36  TRP   L C   1 
ATOM   1911 O  O   . TRP   B 2 36  ? -18.40300 11.39500 -12.56900 1.000 33.39471  ? 36  TRP   L O   1 
ATOM   1912 C  CB  . TRP   B 2 36  ? -20.74900 13.09700 -11.54100 1.000 32.01368  ? 36  TRP   L CB  1 
ATOM   1913 C  CG  . TRP   B 2 36  ? -21.89900 14.05000 -11.61200 1.000 30.87558  ? 36  TRP   L CG  1 
ATOM   1914 C  CD1 . TRP   B 2 36  ? -22.97200 13.97700 -12.44900 1.000 32.34944  ? 36  TRP   L CD1 1 
ATOM   1915 C  CD2 . TRP   B 2 36  ? -22.08800 15.22500 -10.81600 1.000 36.18466  ? 36  TRP   L CD2 1 
ATOM   1916 N  NE1 . TRP   B 2 36  ? -23.82100 15.03300 -12.22200 1.000 33.77906  ? 36  TRP   L NE1 1 
ATOM   1917 C  CE2 . TRP   B 2 36  ? -23.30100 15.81400 -11.22400 1.000 38.87596  ? 36  TRP   L CE2 1 
ATOM   1918 C  CE3 . TRP   B 2 36  ? -21.35100 15.83500 -9.79600  1.000 35.35437  ? 36  TRP   L CE3 1 
ATOM   1919 C  CZ2 . TRP   B 2 36  ? -23.79400 16.98300 -10.64900 1.000 39.27284  ? 36  TRP   L CZ2 1 
ATOM   1920 C  CZ3 . TRP   B 2 36  ? -21.84100 16.99500 -9.22700  1.000 31.55999  ? 36  TRP   L CZ3 1 
ATOM   1921 C  CH2 . TRP   B 2 36  ? -23.05100 17.55600 -9.65400  1.000 36.01967  ? 36  TRP   L CH2 1 
ATOM   1922 N  N   . TYR   B 2 37  ? -17.36100 13.14300 -11.59900 1.000 30.19160  ? 37  TYR   L N   1 
ATOM   1923 C  CA  . TYR   B 2 37  ? -16.17400 12.39900 -11.21700 1.000 27.06933  ? 37  TYR   L CA  1 
ATOM   1924 C  C   . TYR   B 2 37  ? -16.09000 12.31400 -9.70200  1.000 29.71869  ? 37  TYR   L C   1 
ATOM   1925 O  O   . TYR   B 2 37  ? -16.61600 13.16800 -8.98400  1.000 35.81290  ? 37  TYR   L O   1 
ATOM   1926 C  CB  . TYR   B 2 37  ? -14.89700 13.05500 -11.75300 1.000 30.67418  ? 37  TYR   L CB  1 
ATOM   1927 C  CG  . TYR   B 2 37  ? -14.79800 13.12800 -13.25700 1.000 31.60389  ? 37  TYR   L CG  1 
ATOM   1928 C  CD1 . TYR   B 2 37  ? -15.39800 14.16100 -13.96200 1.000 29.85780  ? 37  TYR   L CD1 1 
ATOM   1929 C  CD2 . TYR   B 2 37  ? -14.08700 12.17300 -13.97300 1.000 29.29949  ? 37  TYR   L CD2 1 
ATOM   1930 C  CE1 . TYR   B 2 37  ? -15.30400 14.23700 -15.33600 1.000 30.21217  ? 37  TYR   L CE1 1 
ATOM   1931 C  CE2 . TYR   B 2 37  ? -13.98700 12.24100 -15.34900 1.000 30.47487  ? 37  TYR   L CE2 1 
ATOM   1932 C  CZ  . TYR   B 2 37  ? -14.59700 13.27500 -16.02600 1.000 33.29094  ? 37  TYR   L CZ  1 
ATOM   1933 O  OH  . TYR   B 2 37  ? -14.49900 13.34400 -17.39700 1.000 34.34267  ? 37  TYR   L OH  1 
ATOM   1934 N  N   . GLN   B 2 38  ? -15.42900 11.26800 -9.22700  1.000 32.42088  ? 38  GLN   L N   1 
ATOM   1935 C  CA  . GLN   B 2 38  ? -15.02200 11.15600 -7.83600  1.000 32.00297  ? 38  GLN   L CA  1 
ATOM   1936 C  C   . GLN   B 2 38  ? -13.50300 11.12100 -7.79400  1.000 34.20926  ? 38  GLN   L C   1 
ATOM   1937 O  O   . GLN   B 2 38  ? -12.87600 10.37100 -8.54900  1.000 36.65799  ? 38  GLN   L O   1 
ATOM   1938 C  CB  . GLN   B 2 38  ? -15.60200 9.90100  -7.18100  1.000 39.13622  ? 38  GLN   L CB  1 
ATOM   1939 C  CG  . GLN   B 2 38  ? -15.03600 9.61300  -5.79800  1.000 38.79762  ? 38  GLN   L CG  1 
ATOM   1940 C  CD  . GLN   B 2 38  ? -15.30300 8.19300  -5.33800  1.000 44.46959  ? 38  GLN   L CD  1 
ATOM   1941 O  OE1 . GLN   B 2 38  ? -14.94500 7.23100  -6.01700  1.000 49.10360  ? 38  GLN   L OE1 1 
ATOM   1942 N  NE2 . GLN   B 2 38  ? -15.93200 8.05600  -4.17600  1.000 45.39533  ? 38  GLN   L NE2 1 
ATOM   1943 N  N   . GLN   B 2 39  ? -12.91300 11.94300 -6.93200  1.000 33.78029  ? 39  GLN   L N   1 
ATOM   1944 C  CA  . GLN   B 2 39  ? -11.46600 11.96500 -6.76100  1.000 35.04978  ? 39  GLN   L CA  1 
ATOM   1945 C  C   . GLN   B 2 39  ? -11.13300 11.88000 -5.28300  1.000 37.07904  ? 39  GLN   L C   1 
ATOM   1946 O  O   . GLN   B 2 39  ? -11.58900 12.71000 -4.49000  1.000 40.13747  ? 39  GLN   L O   1 
ATOM   1947 C  CB  . GLN   B 2 39  ? -10.84000 13.22100 -7.36900  1.000 33.72175  ? 39  GLN   L CB  1 
ATOM   1948 C  CG  . GLN   B 2 39  ? -9.33900  13.29300 -7.13600  1.000 34.72135  ? 39  GLN   L CG  1 
ATOM   1949 C  CD  . GLN   B 2 39  ? -8.64500  14.29600 -8.02900  1.000 34.40071  ? 39  GLN   L CD  1 
ATOM   1950 O  OE1 . GLN   B 2 39  ? -9.18100  15.36600 -8.31400  1.000 35.18241  ? 39  GLN   L OE1 1 
ATOM   1951 N  NE2 . GLN   B 2 39  ? -7.44200  13.95500 -8.47800  1.000 40.47987  ? 39  GLN   L NE2 1 
ATOM   1952 N  N   . LYS   B 2 40  ? -10.34200 10.89300 -4.92600  1.000 32.88215  ? 40  LYS   L N   1 
ATOM   1953 C  CA  . LYS   B 2 40  ? -9.76700  10.75400 -3.60400  1.000 41.21818  ? 40  LYS   L CA  1 
ATOM   1954 C  C   . LYS   B 2 40  ? -8.32600  11.23500 -3.61400  1.000 45.71652  ? 40  LYS   L C   1 
ATOM   1955 O  O   . LYS   B 2 40  ? -7.66500  11.22400 -4.65800  1.000 40.52405  ? 40  LYS   L O   1 
ATOM   1956 C  CB  . LYS   B 2 40  ? -9.84500  9.29400  -3.15300  1.000 47.19015  ? 40  LYS   L CB  1 
ATOM   1957 C  CG  . LYS   B 2 40  ? -11.27500 8.84600  -2.94200  1.000 49.42086  ? 40  LYS   L CG  1 
ATOM   1958 C  CD  . LYS   B 2 40  ? -11.45200 7.36300  -3.16000  1.000 45.40269  ? 40  LYS   L CD  1 
ATOM   1959 C  CE  . LYS   B 2 40  ? -12.43700 6.80600  -2.15600  1.000 53.14267  ? 40  LYS   L CE  1 
ATOM   1960 N  NZ  . LYS   B 2 40  ? -13.33100 5.77600  -2.76100  1.000 57.58719  ? 40  LYS   L NZ  1 
ATOM   1961 N  N   . PRO   B 2 41  ? -7.80600  11.67800 -2.46900  1.000 50.02329  ? 41  PRO   L N   1 
ATOM   1962 C  CA  . PRO   B 2 41  ? -6.49400  12.33700 -2.46500  1.000 43.72821  ? 41  PRO   L CA  1 
ATOM   1963 C  C   . PRO   B 2 41  ? -5.38700  11.41300 -2.95300  1.000 49.03245  ? 41  PRO   L C   1 
ATOM   1964 O  O   . PRO   B 2 41  ? -5.34300  10.22800 -2.61600  1.000 42.29937  ? 41  PRO   L O   1 
ATOM   1965 C  CB  . PRO   B 2 41  ? -6.29800  12.72500 -0.99500  1.000 44.69305  ? 41  PRO   L CB  1 
ATOM   1966 C  CG  . PRO   B 2 41  ? -7.67300  12.74200 -0.41900  1.000 51.81311  ? 41  PRO   L CG  1 
ATOM   1967 C  CD  . PRO   B 2 41  ? -8.40900  11.65500 -1.12600  1.000 44.71196  ? 41  PRO   L CD  1 
ATOM   1968 N  N   . GLY   B 2 42  ? -4.49000  11.97300 -3.76300  1.000 50.68410  ? 42  GLY   L N   1 
ATOM   1969 C  CA  . GLY   B 2 42  ? -3.38900  11.22600 -4.33200  1.000 44.39717  ? 42  GLY   L CA  1 
ATOM   1970 C  C   . GLY   B 2 42  ? -3.74900  10.33000 -5.49500  1.000 40.87835  ? 42  GLY   L C   1 
ATOM   1971 O  O   . GLY   B 2 42  ? -2.84800  9.71700  -6.08300  1.000 46.66140  ? 42  GLY   L O   1 
ATOM   1972 N  N   . GLN   B 2 43  ? -5.02500  10.23000 -5.84800  1.000 39.11018  ? 43  GLN   L N   1 
ATOM   1973 C  CA  . GLN   B 2 43  ? -5.48500  9.37900  -6.93400  1.000 36.35337  ? 43  GLN   L CA  1 
ATOM   1974 C  C   . GLN   B 2 43  ? -5.96200  10.22700 -8.10500  1.000 39.92758  ? 43  GLN   L C   1 
ATOM   1975 O  O   . GLN   B 2 43  ? -6.07800  11.45200 -8.01800  1.000 44.72750  ? 43  GLN   L O   1 
ATOM   1976 C  CB  . GLN   B 2 43  ? -6.61500  8.45500  -6.46500  1.000 37.63387  ? 43  GLN   L CB  1 
ATOM   1977 C  CG  . GLN   B 2 43  ? -6.28200  7.59400  -5.26300  1.000 45.57724  ? 43  GLN   L CG  1 
ATOM   1978 C  CD  . GLN   B 2 43  ? -7.41800  6.65500  -4.90200  1.000 45.24928  ? 43  GLN   L CD  1 
ATOM   1979 O  OE1 . GLN   B 2 43  ? -8.55000  6.82900  -5.35500  1.000 46.81348  ? 43  GLN   L OE1 1 
ATOM   1980 N  NE2 . GLN   B 2 43  ? -7.12100  5.65100  -4.08600  1.000 51.32533  ? 43  GLN   L NE2 1 
ATOM   1981 N  N   . ALA   B 2 44  ? -6.24100  9.54600  -9.21100  1.000 37.30817  ? 44  ALA   L N   1 
ATOM   1982 C  CA  . ALA   B 2 44  ? -6.82000  10.13300 -10.40700 1.000 33.77394  ? 44  ALA   L CA  1 
ATOM   1983 C  C   . ALA   B 2 44  ? -8.34000  10.12900 -10.30800 1.000 32.08603  ? 44  ALA   L C   1 
ATOM   1984 O  O   . ALA   B 2 44  ? -8.91800  9.36900  -9.52500  1.000 36.97952  ? 44  ALA   L O   1 
ATOM   1985 C  CB  . ALA   B 2 44  ? -6.36400  9.35500  -11.64100 1.000 35.99057  ? 44  ALA   L CB  1 
ATOM   1986 N  N   . PRO   B 2 45  ? -9.02400  10.98200 -11.07200 1.000 33.75000  ? 45  PRO   L N   1 
ATOM   1987 C  CA  . PRO   B 2 45  ? -10.48900 11.01400 -10.99100 1.000 34.94675  ? 45  PRO   L CA  1 
ATOM   1988 C  C   . PRO   B 2 45  ? -11.11400 9.73500  -11.52600 1.000 31.17748  ? 45  PRO   L C   1 
ATOM   1989 O  O   . PRO   B 2 45  ? -10.67000 9.17300  -12.53000 1.000 33.38579  ? 45  PRO   L O   1 
ATOM   1990 C  CB  . PRO   B 2 45  ? -10.86900 12.22400 -11.85500 1.000 29.38697  ? 45  PRO   L CB  1 
ATOM   1991 C  CG  . PRO   B 2 45  ? -9.63200  13.05000 -11.92100 1.000 32.57316  ? 45  PRO   L CG  1 
ATOM   1992 C  CD  . PRO   B 2 45  ? -8.50200  12.07100 -11.91400 1.000 34.31806  ? 45  PRO   L CD  1 
ATOM   1993 N  N   . ARG   B 2 46  ? -12.15900 9.28100  -10.83900 1.000 33.60276  ? 46  ARG   L N   1 
ATOM   1994 C  CA  . ARG   B 2 46  ? -12.92000 8.09500  -11.21800 1.000 40.34193  ? 46  ARG   L CA  1 
ATOM   1995 C  C   . ARG   B 2 46  ? -14.26600 8.55600  -11.76400 1.000 35.67557  ? 46  ARG   L C   1 
ATOM   1996 O  O   . ARG   B 2 46  ? -15.08700 9.10700  -11.02200 1.000 37.07537  ? 46  ARG   L O   1 
ATOM   1997 C  CB  . ARG   B 2 46  ? -13.09300 7.15800  -10.02300 1.000 37.40525  ? 46  ARG   L CB  1 
ATOM   1998 C  CG  . ARG   B 2 46  ? -14.02300 5.97500  -10.26600 1.000 45.46483  ? 46  ARG   L CG  1 
ATOM   1999 C  CD  . ARG   B 2 46  ? -14.06000 5.05200  -9.05200  1.000 50.75550  ? 46  ARG   L CD  1 
ATOM   2000 N  NE  . ARG   B 2 46  ? -15.42400 4.73200  -8.64100  1.000 50.78171  ? 46  ARG   L NE  1 
ATOM   2001 C  CZ  . ARG   B 2 46  ? -15.76700 4.36600  -7.41000  1.000 53.99069  ? 46  ARG   L CZ  1 
ATOM   2002 N  NH1 . ARG   B 2 46  ? -14.84500 4.27500  -6.46200  1.000 59.70580  ? 46  ARG   L NH1 1 
ATOM   2003 N  NH2 . ARG   B 2 46  ? -17.03300 4.09200  -7.12500  1.000 49.64152  ? 46  ARG   L NH2 1 
ATOM   2004 N  N   . LEU   B 2 47  ? -14.48900 8.33700  -13.05800 1.000 35.22934  ? 47  LEU   L N   1 
ATOM   2005 C  CA  . LEU   B 2 47  ? -15.73000 8.76500  -13.69200 1.000 37.51556  ? 47  LEU   L CA  1 
ATOM   2006 C  C   . LEU   B 2 47  ? -16.90400 7.97200  -13.13000 1.000 41.50478  ? 47  LEU   L C   1 
ATOM   2007 O  O   . LEU   B 2 47  ? -16.92700 6.73900  -13.20900 1.000 43.63386  ? 47  LEU   L O   1 
ATOM   2008 C  CB  . LEU   B 2 47  ? -15.64300 8.59500  -15.20700 1.000 30.77129  ? 47  LEU   L CB  1 
ATOM   2009 C  CG  . LEU   B 2 47  ? -16.89600 8.99000  -15.99600 1.000 31.95764  ? 47  LEU   L CG  1 
ATOM   2010 C  CD1 . LEU   B 2 47  ? -16.95600 10.49500 -16.21300 1.000 33.36433  ? 47  LEU   L CD1 1 
ATOM   2011 C  CD2 . LEU   B 2 47  ? -16.96300 8.25600  -17.32700 1.000 33.74301  ? 47  LEU   L CD2 1 
ATOM   2012 N  N   . LEU   B 2 48  ? -17.87600 8.68200  -12.55700 1.000 33.70399  ? 48  LEU   L N   1 
ATOM   2013 C  CA  . LEU   B 2 48  ? -19.08500 8.06900  -12.02000 1.000 34.25341  ? 48  LEU   L CA  1 
ATOM   2014 C  C   . LEU   B 2 48  ? -20.22400 8.09400  -13.03300 1.000 34.02122  ? 48  LEU   L C   1 
ATOM   2015 O  O   . LEU   B 2 48  ? -20.76200 7.04700  -13.40300 1.000 39.58198  ? 48  LEU   L O   1 
ATOM   2016 C  CB  . LEU   B 2 48  ? -19.51100 8.78600  -10.73100 1.000 35.85864  ? 48  LEU   L CB  1 
ATOM   2017 C  CG  . LEU   B 2 48  ? -18.53400 8.78300  -9.55500  1.000 34.12926  ? 48  LEU   L CG  1 
ATOM   2018 C  CD1 . LEU   B 2 48  ? -19.07800 9.63300  -8.42000  1.000 32.18852  ? 48  LEU   L CD1 1 
ATOM   2019 C  CD2 . LEU   B 2 48  ? -18.26800 7.36400  -9.08300  1.000 38.44494  ? 48  LEU   L CD2 1 
ATOM   2020 N  N   . ILE   B 2 49  ? -20.60200 9.28600  -13.48600 1.000 40.18725  ? 49  ILE   L N   1 
ATOM   2021 C  CA  . ILE   B 2 49  ? -21.71900 9.47500  -14.39900 1.000 38.90701  ? 49  ILE   L CA  1 
ATOM   2022 C  C   . ILE   B 2 49  ? -21.22600 10.25500 -15.60800 1.000 38.82162  ? 49  ILE   L C   1 
ATOM   2023 O  O   . ILE   B 2 49  ? -20.25800 11.01600 -15.52400 1.000 40.44113  ? 49  ILE   L O   1 
ATOM   2024 C  CB  . ILE   B 2 49  ? -22.89100 10.21600 -13.71200 1.000 40.14142  ? 49  ILE   L CB  1 
ATOM   2025 C  CG1 . ILE   B 2 49  ? -23.22600 9.57000  -12.36800 1.000 37.55451  ? 49  ILE   L CG1 1 
ATOM   2026 C  CG2 . ILE   B 2 49  ? -24.12500 10.22600 -14.59300 1.000 43.42831  ? 49  ILE   L CG2 1 
ATOM   2027 C  CD1 . ILE   B 2 49  ? -23.96600 8.26100  -12.49500 1.000 40.92333  ? 49  ILE   L CD1 1 
ATOM   2028 N  N   . TYR   B 2 50  ? -21.88000 10.03400 -16.74600 1.000 39.93930  ? 50  TYR   L N   1 
ATOM   2029 C  CA  . TYR   B 2 50  ? -21.74100 10.90400 -17.90300 1.000 42.29845  ? 50  TYR   L CA  1 
ATOM   2030 C  C   . TYR   B 2 50  ? -23.03600 10.83700 -18.69800 1.000 44.85543  ? 50  TYR   L C   1 
ATOM   2031 O  O   . TYR   B 2 50  ? -23.85500 9.93400  -18.50500 1.000 47.56936  ? 50  TYR   L O   1 
ATOM   2032 C  CB  . TYR   B 2 50  ? -20.52700 10.53500 -18.76800 1.000 42.64363  ? 50  TYR   L CB  1 
ATOM   2033 C  CG  . TYR   B 2 50  ? -20.61300 9.20000  -19.47000 1.000 45.02726  ? 50  TYR   L CG  1 
ATOM   2034 C  CD1 . TYR   B 2 50  ? -20.43200 8.01300  -18.77300 1.000 44.69990  ? 50  TYR   L CD1 1 
ATOM   2035 C  CD2 . TYR   B 2 50  ? -20.85500 9.12700  -20.83600 1.000 49.16166  ? 50  TYR   L CD2 1 
ATOM   2036 C  CE1 . TYR   B 2 50  ? -20.50200 6.79100  -19.41400 1.000 42.52349  ? 50  TYR   L CE1 1 
ATOM   2037 C  CE2 . TYR   B 2 50  ? -20.92600 7.91100  -21.48500 1.000 45.50336  ? 50  TYR   L CE2 1 
ATOM   2038 C  CZ  . TYR   B 2 50  ? -20.74800 6.74700  -20.77000 1.000 45.28289  ? 50  TYR   L CZ  1 
ATOM   2039 O  OH  . TYR   B 2 50  ? -20.81900 5.53400  -21.41500 1.000 51.01169  ? 50  TYR   L OH  1 
ATOM   2040 N  N   . ASP   B 2 51  ? -23.21600 11.81300 -19.58900 1.000 44.60208  ? 51  ASP   L N   1 
ATOM   2041 C  CA  . ASP   B 2 51  ? -24.49200 12.02700 -20.27200 1.000 47.26778  ? 51  ASP   L CA  1 
ATOM   2042 C  C   . ASP   B 2 51  ? -25.61100 12.23300 -19.25000 1.000 49.03863  ? 51  ASP   L C   1 
ATOM   2043 O  O   . ASP   B 2 51  ? -26.69300 11.65100 -19.34800 1.000 45.69565  ? 51  ASP   L O   1 
ATOM   2044 C  CB  . ASP   B 2 51  ? -24.81600 10.87400 -21.22800 1.000 48.21825  ? 51  ASP   L CB  1 
ATOM   2045 C  CG  . ASP   B 2 51  ? -24.21400 11.07300 -22.60700 1.000 58.98429  ? 51  ASP   L CG  1 
ATOM   2046 O  OD1 . ASP   B 2 51  ? -23.01300 11.40600 -22.69300 1.000 54.89844  ? 51  ASP   L OD1 1 
ATOM   2047 O  OD2 . ASP   B 2 51  ? -24.94200 10.89200 -23.60600 1.000 62.30440  ? 51  ASP   L OD2 1 
ATOM   2048 N  N   . THR   B 2 52  ? -25.31600 13.05900 -18.24200 1.000 49.41171  ? 52  THR   L N   1 
ATOM   2049 C  CA  . THR   B 2 52  ? -26.23100 13.42100 -17.16100 1.000 44.15871  ? 52  THR   L CA  1 
ATOM   2050 C  C   . THR   B 2 52  ? -26.56300 12.24800 -16.23900 1.000 45.00674  ? 52  THR   L C   1 
ATOM   2051 O  O   . THR   B 2 52  ? -26.53000 12.40100 -15.01300 1.000 45.04391  ? 52  THR   L O   1 
ATOM   2052 C  CB  . THR   B 2 52  ? -27.52500 14.03400 -17.71800 1.000 47.24505  ? 52  THR   L CB  1 
ATOM   2053 O  OG1 . THR   B 2 52  ? -27.26200 15.35600 -18.20700 1.000 49.78207  ? 52  THR   L OG1 1 
ATOM   2054 C  CG2 . THR   B 2 52  ? -28.59800 14.10400 -16.63600 1.000 38.34485  ? 52  THR   L CG2 1 
ATOM   2055 N  N   . SER   B 2 53  ? -26.86900 11.07600 -16.80000 1.000 45.93420  ? 53  SER   L N   1 
ATOM   2056 C  CA  . SER   B 2 53  ? -27.42000 10.00200 -15.98400 1.000 43.21414  ? 53  SER   L CA  1 
ATOM   2057 C  C   . SER   B 2 53  ? -26.87200 8.60700  -16.26200 1.000 46.76117  ? 53  SER   L C   1 
ATOM   2058 O  O   . SER   B 2 53  ? -27.18500 7.70300  -15.48400 1.000 50.43872  ? 53  SER   L O   1 
ATOM   2059 C  CB  . SER   B 2 53  ? -28.94900 9.96500  -16.12800 1.000 46.02397  ? 53  SER   L CB  1 
ATOM   2060 O  OG  . SER   B 2 53  ? -29.32000 9.57600  -17.43600 1.000 52.04222  ? 53  SER   L OG  1 
ATOM   2061 N  N   . ARG   B 2 54  ? -26.07000 8.37700  -17.30000 1.000 49.35882  ? 54  ARG   L N   1 
ATOM   2062 C  CA  . ARG   B 2 54  ? -25.59700 7.01800  -17.55500 1.000 44.74911  ? 54  ARG   L CA  1 
ATOM   2063 C  C   . ARG   B 2 54  ? -24.45500 6.67400  -16.60600 1.000 48.64458  ? 54  ARG   L C   1 
ATOM   2064 O  O   . ARG   B 2 54  ? -23.40100 7.31900  -16.63000 1.000 49.12834  ? 54  ARG   L O   1 
ATOM   2065 C  CB  . ARG   B 2 54  ? -25.14900 6.83600  -19.00200 1.000 41.15400  ? 54  ARG   L CB  1 
ATOM   2066 C  CG  . ARG   B 2 54  ? -24.99700 5.36500  -19.37000 1.000 52.83972  ? 54  ARG   L CG  1 
ATOM   2067 C  CD  . ARG   B 2 54  ? -23.77200 5.09300  -20.24200 1.000 58.19434  ? 54  ARG   L CD  1 
ATOM   2068 N  NE  . ARG   B 2 54  ? -23.91300 5.62600  -21.59700 1.000 65.93958  ? 54  ARG   L NE  1 
ATOM   2069 C  CZ  . ARG   B 2 54  ? -24.83000 5.23500  -22.47900 1.000 67.23879  ? 54  ARG   L CZ  1 
ATOM   2070 N  NH1 . ARG   B 2 54  ? -25.70100 4.28000  -22.17700 1.000 62.82837  ? 54  ARG   L NH1 1 
ATOM   2071 N  NH2 . ARG   B 2 54  ? -24.86800 5.79600  -23.67900 1.000 72.77141  ? 54  ARG   L NH2 1 
ATOM   2072 N  N   . ARG   B 2 55  ? -24.66400 5.65900  -15.77300 1.000 48.78267  ? 55  ARG   L N   1 
ATOM   2073 C  CA  . ARG   B 2 55  ? -23.61400 5.19400  -14.88000 1.000 41.72690  ? 55  ARG   L CA  1 
ATOM   2074 C  C   . ARG   B 2 55  ? -22.46500 4.59500  -15.68000 1.000 41.82238  ? 55  ARG   L C   1 
ATOM   2075 O  O   . ARG   B 2 55  ? -22.67900 3.84600  -16.63700 1.000 51.01044  ? 55  ARG   L O   1 
ATOM   2076 C  CB  . ARG   B 2 55  ? -24.16800 4.15500  -13.90500 1.000 42.69920  ? 55  ARG   L CB  1 
ATOM   2077 C  CG  . ARG   B 2 55  ? -24.51200 4.70500  -12.53600 1.000 49.66201  ? 55  ARG   L CG  1 
ATOM   2078 C  CD  . ARG   B 2 55  ? -24.95400 3.60000  -11.59300 1.000 51.05374  ? 55  ARG   L CD  1 
ATOM   2079 N  NE  . ARG   B 2 55  ? -26.26300 3.05800  -11.94800 1.000 57.08785  ? 55  ARG   L NE  1 
ATOM   2080 C  CZ  . ARG   B 2 55  ? -26.45200 1.88700  -12.54800 1.000 63.79088  ? 55  ARG   L CZ  1 
ATOM   2081 N  NH1 . ARG   B 2 55  ? -25.41400 1.12400  -12.86900 1.000 62.60454  ? 55  ARG   L NH1 1 
ATOM   2082 N  NH2 . ARG   B 2 55  ? -27.68100 1.47700  -12.82900 1.000 63.25108  ? 55  ARG   L NH2 1 
ATOM   2083 N  N   . ALA   B 2 56  ? -21.24100 4.93800  -15.29100 1.000 39.13676  ? 56  ALA   L N   1 
ATOM   2084 C  CA  . ALA   B 2 56  ? -20.07700 4.32000  -15.90200 1.000 45.52247  ? 56  ALA   L CA  1 
ATOM   2085 C  C   . ALA   B 2 56  ? -20.01400 2.84400  -15.52500 1.000 50.86655  ? 56  ALA   L C   1 
ATOM   2086 O  O   . ALA   B 2 56  ? -20.68100 2.38400  -14.59400 1.000 59.48942  ? 56  ALA   L O   1 
ATOM   2087 C  CB  . ALA   B 2 56  ? -18.79700 5.03500  -15.47000 1.000 42.89654  ? 56  ALA   L CB  1 
ATOM   2088 N  N   . THR   B 2 57  ? -19.20100 2.09500  -16.26400 1.000 50.61773  ? 57  THR   L N   1 
ATOM   2089 C  CA  . THR   B 2 57  ? -19.12400 0.65700  -16.04500 1.000 56.53165  ? 57  THR   L CA  1 
ATOM   2090 C  C   . THR   B 2 57  ? -18.51400 0.35200  -14.67700 1.000 59.66386  ? 57  THR   L C   1 
ATOM   2091 O  O   . THR   B 2 57  ? -17.43400 0.84600  -14.33700 1.000 61.01107  ? 57  THR   L O   1 
ATOM   2092 C  CB  . THR   B 2 57  ? -18.32800 -0.01200 -17.17200 1.000 55.92045  ? 57  THR   L CB  1 
ATOM   2093 O  OG1 . THR   B 2 57  ? -18.28700 -1.42900 -16.96100 1.000 59.95003  ? 57  THR   L OG1 1 
ATOM   2094 C  CG2 . THR   B 2 57  ? -16.90600 0.54300  -17.28000 1.000 53.05996  ? 57  THR   L CG2 1 
ATOM   2095 N  N   . GLY   B 2 58  ? -19.23400 -0.43300 -13.87900 1.000 61.29658  ? 58  GLY   L N   1 
ATOM   2096 C  CA  . GLY   B 2 58  ? -18.74300 -0.88600 -12.59300 1.000 59.67713  ? 58  GLY   L CA  1 
ATOM   2097 C  C   . GLY   B 2 58  ? -19.03200 0.00900  -11.40600 1.000 54.38238  ? 58  GLY   L C   1 
ATOM   2098 O  O   . GLY   B 2 58  ? -18.47300 -0.23000 -10.32900 1.000 47.27842  ? 58  GLY   L O   1 
ATOM   2099 N  N   . ILE   B 2 59  ? -19.88000 1.01700  -11.55500 1.000 54.41524  ? 59  ILE   L N   1 
ATOM   2100 C  CA  . ILE   B 2 59  ? -20.15400 1.98600  -10.49400 1.000 53.32595  ? 59  ILE   L CA  1 
ATOM   2101 C  C   . ILE   B 2 59  ? -21.41100 1.54600  -9.74600  1.000 45.17218  ? 59  ILE   L C   1 
ATOM   2102 O  O   . ILE   B 2 59  ? -22.41000 1.20600  -10.39300 1.000 42.53843  ? 59  ILE   L O   1 
ATOM   2103 C  CB  . ILE   B 2 59  ? -20.32100 3.40900  -11.05700 1.000 51.09557  ? 59  ILE   L CB  1 
ATOM   2104 C  CG1 . ILE   B 2 59  ? -19.11400 3.77200  -11.92600 1.000 49.68543  ? 59  ILE   L CG1 1 
ATOM   2105 C  CG2 . ILE   B 2 59  ? -20.50300 4.41700  -9.93200  1.000 45.36106  ? 59  ILE   L CG2 1 
ATOM   2106 C  CD1 . ILE   B 2 59  ? -17.89700 4.19500  -11.13300 1.000 44.80996  ? 59  ILE   L CD1 1 
ATOM   2107 N  N   . PRO   B 2 60  ? -21.39900 1.53500  -8.39500  1.000 43.53328  ? 60  PRO   L N   1 
ATOM   2108 C  CA  . PRO   B 2 60  ? -22.58700 1.09700  -7.63800  1.000 48.52189  ? 60  PRO   L CA  1 
ATOM   2109 C  C   . PRO   B 2 60  ? -23.86900 1.83900  -7.98800  1.000 53.48225  ? 60  PRO   L C   1 
ATOM   2110 O  O   . PRO   B 2 60  ? -23.83600 2.98800  -8.44000  1.000 52.40113  ? 60  PRO   L O   1 
ATOM   2111 C  CB  . PRO   B 2 60  ? -22.18700 1.36200  -6.18100  1.000 46.69508  ? 60  PRO   L CB  1 
ATOM   2112 C  CG  . PRO   B 2 60  ? -20.70200 1.28000  -6.17900  1.000 45.38867  ? 60  PRO   L CG  1 
ATOM   2113 C  CD  . PRO   B 2 60  ? -20.24600 1.80100  -7.51500  1.000 42.19652  ? 60  PRO   L CD  1 
ATOM   2114 N  N   . ASP   B 2 61  ? -25.01100 1.18300  -7.75700  1.000 59.69851  ? 61  ASP   L N   1 
ATOM   2115 C  CA  . ASP   B 2 61  ? -26.29900 1.73800  -8.15600  1.000 58.68222  ? 61  ASP   L CA  1 
ATOM   2116 C  C   . ASP   B 2 61  ? -26.68300 2.97600  -7.35500  1.000 57.11842  ? 61  ASP   L C   1 
ATOM   2117 O  O   . ASP   B 2 61  ? -27.53700 3.74600  -7.80600  1.000 58.36717  ? 61  ASP   L O   1 
ATOM   2118 C  CB  . ASP   B 2 61  ? -27.39600 0.67600  -8.03400  1.000 58.44539  ? 61  ASP   L CB  1 
ATOM   2119 C  CG  . ASP   B 2 61  ? -27.42700 0.01100  -6.66800  1.000 80.72053  ? 61  ASP   L CG  1 
ATOM   2120 O  OD1 . ASP   B 2 61  ? -26.86800 0.57500  -5.70300  1.000 74.16729  ? 61  ASP   L OD1 1 
ATOM   2121 O  OD2 . ASP   B 2 61  ? -28.02200 -1.08100 -6.55800  1.000 84.25808  ? 61  ASP   L OD2 1 
ATOM   2122 N  N   . ARG   B 2 62  ? -26.07600 3.19100  -6.18500  1.000 53.87026  ? 62  ARG   L N   1 
ATOM   2123 C  CA  . ARG   B 2 62  ? -26.43900 4.35600  -5.38400  1.000 54.81153  ? 62  ARG   L CA  1 
ATOM   2124 C  C   . ARG   B 2 62  ? -26.06100 5.65800  -6.07900  1.000 56.48581  ? 62  ARG   L C   1 
ATOM   2125 O  O   . ARG   B 2 62  ? -26.69600 6.69200  -5.84200  1.000 56.28023  ? 62  ARG   L O   1 
ATOM   2126 C  CB  . ARG   B 2 62  ? -25.78600 4.27800  -4.00400  1.000 55.48499  ? 62  ARG   L CB  1 
ATOM   2127 C  CG  . ARG   B 2 62  ? -24.37300 3.70900  -3.98700  1.000 55.49867  ? 62  ARG   L CG  1 
ATOM   2128 C  CD  . ARG   B 2 62  ? -24.00200 3.24700  -2.58100  1.000 59.78246  ? 62  ARG   L CD  1 
ATOM   2129 N  NE  . ARG   B 2 62  ? -22.56600 3.03100  -2.41400  1.000 59.22894  ? 62  ARG   L NE  1 
ATOM   2130 C  CZ  . ARG   B 2 62  ? -21.69100 3.99300  -2.13600  1.000 54.47717  ? 62  ARG   L CZ  1 
ATOM   2131 N  NH1 . ARG   B 2 62  ? -22.10300 5.24400  -1.98900  1.000 54.03845  ? 62  ARG   L NH1 1 
ATOM   2132 N  NH2 . ARG   B 2 62  ? -20.40400 3.70500  -2.00400  1.000 53.06716  ? 62  ARG   L NH2 1 
ATOM   2133 N  N   . PHE   B 2 63  ? -25.04100 5.62900  -6.93400  1.000 52.22576  ? 63  PHE   L N   1 
ATOM   2134 C  CA  . PHE   B 2 63  ? -24.64100 6.80400  -7.70000  1.000 45.72599  ? 63  PHE   L CA  1 
ATOM   2135 C  C   . PHE   B 2 63  ? -25.59900 6.97900  -8.87100  1.000 46.14529  ? 63  PHE   L C   1 
ATOM   2136 O  O   . PHE   B 2 63  ? -25.56100 6.20700  -9.83400  1.000 52.13475  ? 63  PHE   L O   1 
ATOM   2137 C  CB  . PHE   B 2 63  ? -23.20400 6.65900  -8.19000  1.000 45.95987  ? 63  PHE   L CB  1 
ATOM   2138 C  CG  . PHE   B 2 63  ? -22.18700 6.60700  -7.08700  1.000 47.08657  ? 63  PHE   L CG  1 
ATOM   2139 C  CD1 . PHE   B 2 63  ? -21.77300 7.76900  -6.45800  1.000 41.53919  ? 63  PHE   L CD1 1 
ATOM   2140 C  CD2 . PHE   B 2 63  ? -21.64400 5.39900  -6.68100  1.000 47.20803  ? 63  PHE   L CD2 1 
ATOM   2141 C  CE1 . PHE   B 2 63  ? -20.83600 7.72800  -5.44500  1.000 42.21315  ? 63  PHE   L CE1 1 
ATOM   2142 C  CE2 . PHE   B 2 63  ? -20.70600 5.35100  -5.66600  1.000 46.51238  ? 63  PHE   L CE2 1 
ATOM   2143 C  CZ  . PHE   B 2 63  ? -20.30100 6.51800  -5.04800  1.000 46.26627  ? 63  PHE   L CZ  1 
ATOM   2144 N  N   . SER   B 2 64  ? -26.46100 7.98800  -8.79100  1.000 47.15322  ? 64  SER   L N   1 
ATOM   2145 C  CA  . SER   B 2 64  ? -27.38500 8.31000  -9.86700  1.000 45.67578  ? 64  SER   L CA  1 
ATOM   2146 C  C   . SER   B 2 64  ? -27.28800 9.79400  -10.18600 1.000 51.00971  ? 64  SER   L C   1 
ATOM   2147 O  O   . SER   B 2 64  ? -27.07800 10.62600 -9.29700  1.000 48.20731  ? 64  SER   L O   1 
ATOM   2148 C  CB  . SER   B 2 64  ? -28.83000 7.94100  -9.50400  1.000 44.19037  ? 64  SER   L CB  1 
ATOM   2149 O  OG  . SER   B 2 64  ? -29.21900 8.54100  -8.28100  1.000 54.56821  ? 64  SER   L OG  1 
ATOM   2150 N  N   . GLY   B 2 65  ? -27.43500 10.11600 -11.46200 1.000 40.10126  ? 65  GLY   L N   1 
ATOM   2151 C  CA  . GLY   B 2 65  ? -27.35300 11.49000 -11.93300 1.000 41.17149  ? 65  GLY   L CA  1 
ATOM   2152 C  C   . GLY   B 2 65  ? -28.67300 11.94100 -12.52400 1.000 47.04158  ? 65  GLY   L C   1 
ATOM   2153 O  O   . GLY   B 2 65  ? -29.35400 11.16900 -13.20100 1.000 44.71604  ? 65  GLY   L O   1 
ATOM   2154 N  N   . SER   B 2 66  ? -29.02900 13.19500 -12.26200 1.000 47.61447  ? 66  SER   L N   1 
ATOM   2155 C  CA  . SER   B 2 66  ? -30.26200 13.78200 -12.76200 1.000 41.09821  ? 66  SER   L CA  1 
ATOM   2156 C  C   . SER   B 2 66  ? -29.94700 15.13700 -13.38200 1.000 42.32614  ? 66  SER   L C   1 
ATOM   2157 O  O   . SER   B 2 66  ? -28.79600 15.58600 -13.40100 1.000 45.41769  ? 66  SER   L O   1 
ATOM   2158 C  CB  . SER   B 2 66  ? -31.30300 13.92900 -11.64400 1.000 43.57298  ? 66  SER   L CB  1 
ATOM   2159 O  OG  . SER   B 2 66  ? -31.24200 12.84000 -10.74000 1.000 55.75594  ? 66  SER   L OG  1 
ATOM   2160 N  N   . GLY   B 2 67  ? -30.97900 15.78600 -13.90000 1.000 38.18461  ? 67  GLY   L N   1 
ATOM   2161 C  CA  . GLY   B 2 67  ? -30.88100 17.16300 -14.33900 1.000 42.07789  ? 67  GLY   L CA  1 
ATOM   2162 C  C   . GLY   B 2 67  ? -31.00200 17.30900 -15.84700 1.000 43.63048  ? 67  GLY   L C   1 
ATOM   2163 O  O   . GLY   B 2 67  ? -31.06900 16.33800 -16.60300 1.000 44.40651  ? 67  GLY   L O   1 
ATOM   2164 N  N   . SER   B 2 68  ? -31.01700 18.57200 -16.26600 1.000 47.82687  ? 68  SER   L N   1 
ATOM   2165 C  CA  . SER   B 2 68  ? -31.16700 18.95600 -17.66300 1.000 48.76413  ? 68  SER   L CA  1 
ATOM   2166 C  C   . SER   B 2 68  ? -30.88200 20.44500 -17.79900 1.000 48.69827  ? 68  SER   L C   1 
ATOM   2167 O  O   . SER   B 2 68  ? -31.06400 21.21100 -16.84700 1.000 44.79250  ? 68  SER   L O   1 
ATOM   2168 C  CB  . SER   B 2 68  ? -32.57600 18.63200 -18.18300 1.000 48.86726  ? 68  SER   L CB  1 
ATOM   2169 O  OG  . SER   B 2 68  ? -32.77900 19.15500 -19.48300 1.000 57.15811  ? 68  SER   L OG  1 
ATOM   2170 N  N   . ALA   B 2 69  ? -30.42800 20.83800 -18.99200 1.000 47.75518  ? 69  ALA   L N   1 
ATOM   2171 C  CA  . ALA   B 2 69  ? -30.18500 22.23400 -19.34800 1.000 44.07342  ? 69  ALA   L CA  1 
ATOM   2172 C  C   . ALA   B 2 69  ? -29.10800 22.87800 -18.48300 1.000 39.41797  ? 69  ALA   L C   1 
ATOM   2173 O  O   . ALA   B 2 69  ? -27.92000 22.81800 -18.81600 1.000 41.88215  ? 69  ALA   L O   1 
ATOM   2174 C  CB  . ALA   B 2 69  ? -31.48100 23.04800 -19.26400 1.000 41.28104  ? 69  ALA   L CB  1 
ATOM   2175 N  N   . THR   B 2 70  ? -29.51100 23.51200 -17.38000 1.000 38.76665  ? 70  THR   L N   1 
ATOM   2176 C  CA  . THR   B 2 70  ? -28.58800 24.25700 -16.53400 1.000 37.35557  ? 70  THR   L CA  1 
ATOM   2177 C  C   . THR   B 2 70  ? -28.54200 23.76500 -15.09500 1.000 39.34994  ? 70  THR   L C   1 
ATOM   2178 O  O   . THR   B 2 70  ? -27.78500 24.32400 -14.29400 1.000 44.01839  ? 70  THR   L O   1 
ATOM   2179 C  CB  . THR   B 2 70  ? -28.94700 25.75100 -16.53200 1.000 43.20410  ? 70  THR   L CB  1 
ATOM   2180 O  OG1 . THR   B 2 70  ? -30.19300 25.94200 -15.85200 1.000 45.22319  ? 70  THR   L OG1 1 
ATOM   2181 C  CG2 . THR   B 2 70  ? -29.07100 26.27800 -17.95200 1.000 32.48917  ? 70  THR   L CG2 1 
ATOM   2182 N  N   . ASP   B 2 71  ? -29.32300 22.74800 -14.73600 1.000 41.95997  ? 71  ASP   L N   1 
ATOM   2183 C  CA  . ASP   B 2 71  ? -29.40000 22.26500 -13.36000 1.000 41.23202  ? 71  ASP   L CA  1 
ATOM   2184 C  C   . ASP   B 2 71  ? -29.22700 20.75400 -13.36700 1.000 44.31356  ? 71  ASP   L C   1 
ATOM   2185 O  O   . ASP   B 2 71  ? -30.10900 20.03200 -13.83900 1.000 49.66522  ? 71  ASP   L O   1 
ATOM   2186 C  CB  . ASP   B 2 71  ? -30.73000 22.65600 -12.71500 1.000 39.69534  ? 71  ASP   L CB  1 
ATOM   2187 C  CG  . ASP   B 2 71  ? -30.68800 24.03200 -12.08400 1.000 62.83034  ? 71  ASP   L CG  1 
ATOM   2188 O  OD1 . ASP   B 2 71  ? -31.09600 25.00600 -12.75100 1.000 60.75677  ? 71  ASP   L OD1 1 
ATOM   2189 O  OD2 . ASP   B 2 71  ? -30.25200 24.14000 -10.91900 1.000 69.90925  ? 71  ASP   L OD2 1 
ATOM   2190 N  N   . PHE   B 2 72  ? -28.10100 20.27700 -12.84100 1.000 42.00383  ? 72  PHE   L N   1 
ATOM   2191 C  CA  . PHE   B 2 72  ? -27.80200 18.85400 -12.78700 1.000 42.52884  ? 72  PHE   L CA  1 
ATOM   2192 C  C   . PHE   B 2 72  ? -27.52500 18.43800 -11.34900 1.000 40.31677  ? 72  PHE   L C   1 
ATOM   2193 O  O   . PHE   B 2 72  ? -27.05400 19.23600 -10.53200 1.000 38.50951  ? 72  PHE   L O   1 
ATOM   2194 C  CB  . PHE   B 2 72  ? -26.60700 18.50200 -13.68100 1.000 39.90725  ? 72  PHE   L CB  1 
ATOM   2195 C  CG  . PHE   B 2 72  ? -26.73200 19.02000 -15.08600 1.000 41.67952  ? 72  PHE   L CG  1 
ATOM   2196 C  CD1 . PHE   B 2 72  ? -27.38600 18.27800 -16.05700 1.000 41.95495  ? 72  PHE   L CD1 1 
ATOM   2197 C  CD2 . PHE   B 2 72  ? -26.20200 20.25100 -15.43400 1.000 41.18872  ? 72  PHE   L CD2 1 
ATOM   2198 C  CE1 . PHE   B 2 72  ? -27.50500 18.75400 -17.34900 1.000 47.05274  ? 72  PHE   L CE1 1 
ATOM   2199 C  CE2 . PHE   B 2 72  ? -26.31800 20.73200 -16.72300 1.000 33.13115  ? 72  PHE   L CE2 1 
ATOM   2200 C  CZ  . PHE   B 2 72  ? -26.97000 19.98300 -17.68200 1.000 42.88716  ? 72  PHE   L CZ  1 
ATOM   2201 N  N   . THR   B 2 73  ? -27.81800 17.17500 -11.04800 1.000 39.39440  ? 73  THR   L N   1 
ATOM   2202 C  CA  . THR   B 2 73  ? -27.75500 16.65900 -9.68900  1.000 39.23930  ? 73  THR   L CA  1 
ATOM   2203 C  C   . THR   B 2 73  ? -27.02700 15.32300 -9.66300  1.000 38.86231  ? 73  THR   L C   1 
ATOM   2204 O  O   . THR   B 2 73  ? -27.09900 14.53700 -10.61200 1.000 42.86648  ? 73  THR   L O   1 
ATOM   2205 C  CB  . THR   B 2 73  ? -29.16400 16.49200 -9.09500  1.000 42.57213  ? 73  THR   L CB  1 
ATOM   2206 O  OG1 . THR   B 2 73  ? -29.98200 17.60300 -9.48100  1.000 41.44889  ? 73  THR   L OG1 1 
ATOM   2207 C  CG2 . THR   B 2 73  ? -29.10600 16.41800 -7.57600  1.000 35.84109  ? 73  THR   L CG2 1 
ATOM   2208 N  N   . LEU   B 2 74  ? -26.32200 15.07500 -8.56000  1.000 37.63492  ? 74  LEU   L N   1 
ATOM   2209 C  CA  . LEU   B 2 74  ? -25.69700 13.78500 -8.29200  1.000 41.80878  ? 74  LEU   L CA  1 
ATOM   2210 C  C   . LEU   B 2 74  ? -26.16000 13.30600 -6.92500  1.000 39.79862  ? 74  LEU   L C   1 
ATOM   2211 O  O   . LEU   B 2 74  ? -25.95400 13.99600 -5.92200  1.000 41.58459  ? 74  LEU   L O   1 
ATOM   2212 C  CB  . LEU   B 2 74  ? -24.16900 13.87500 -8.34200  1.000 37.40683  ? 74  LEU   L CB  1 
ATOM   2213 C  CG  . LEU   B 2 74  ? -23.44500 12.62000 -7.84800  1.000 35.18082  ? 74  LEU   L CG  1 
ATOM   2214 C  CD1 . LEU   B 2 74  ? -23.63900 11.46700 -8.82300  1.000 34.35104  ? 74  LEU   L CD1 1 
ATOM   2215 C  CD2 . LEU   B 2 74  ? -21.96500 12.89100 -7.62100  1.000 33.28120  ? 74  LEU   L CD2 1 
ATOM   2216 N  N   . THR   B 2 75  ? -26.78100 12.13200 -6.88800  1.000 42.77999  ? 75  THR   L N   1 
ATOM   2217 C  CA  . THR   B 2 75  ? -27.35800 11.58300 -5.67000  1.000 46.84404  ? 75  THR   L CA  1 
ATOM   2218 C  C   . THR   B 2 75  ? -26.58400 10.34800 -5.23400  1.000 50.29008  ? 75  THR   L C   1 
ATOM   2219 O  O   . THR   B 2 75  ? -26.24800 9.48900  -6.05600  1.000 54.58517  ? 75  THR   L O   1 
ATOM   2220 C  CB  . THR   B 2 75  ? -28.83300 11.22700 -5.88000  1.000 50.67492  ? 75  THR   L CB  1 
ATOM   2221 O  OG1 . THR   B 2 75  ? -29.56000 12.40300 -6.25800  1.000 44.70413  ? 75  THR   L OG1 1 
ATOM   2222 C  CG2 . THR   B 2 75  ? -29.43600 10.65000 -4.60900  1.000 48.64479  ? 75  THR   L CG2 1 
ATOM   2223 N  N   . ILE   B 2 76  ? -26.29900 10.26600 -3.93800  1.000 48.62738  ? 76  ILE   L N   1 
ATOM   2224 C  CA  . ILE   B 2 76  ? -25.58600 9.13300  -3.34700  1.000 49.93500  ? 76  ILE   L CA  1 
ATOM   2225 C  C   . ILE   B 2 76  ? -26.49900 8.58100  -2.26300  1.000 57.41362  ? 76  ILE   L C   1 
ATOM   2226 O  O   . ILE   B 2 76  ? -26.47100 9.03300  -1.11100  1.000 58.14645  ? 76  ILE   L O   1 
ATOM   2227 C  CB  . ILE   B 2 76  ? -24.21600 9.53200  -2.78900  1.000 46.04945  ? 76  ILE   L CB  1 
ATOM   2228 C  CG1 . ILE   B 2 76  ? -23.52000 10.49400 -3.75800  1.000 45.86716  ? 76  ILE   L CG1 1 
ATOM   2229 C  CG2 . ILE   B 2 76  ? -23.35700 8.30600  -2.55500  1.000 47.51365  ? 76  ILE   L CG2 1 
ATOM   2230 C  CD1 . ILE   B 2 76  ? -22.21300 11.05400 -3.25300  1.000 35.09555  ? 76  ILE   L CD1 1 
ATOM   2231 N  N   . SER   B 2 77  ? -27.32300 7.59000  -2.61900  1.000 58.71169  ? 77  SER   L N   1 
ATOM   2232 C  CA  . SER   B 2 77  ? -28.43300 7.17800  -1.76500  1.000 58.69524  ? 77  SER   L CA  1 
ATOM   2233 C  C   . SER   B 2 77  ? -27.93600 6.61700  -0.43500  1.000 64.17980  ? 77  SER   L C   1 
ATOM   2234 O  O   . SER   B 2 77  ? -28.28100 7.13000  0.63500   1.000 68.38496  ? 77  SER   L O   1 
ATOM   2235 C  CB  . SER   B 2 77  ? -29.30200 6.16300  -2.50900  1.000 64.22891  ? 77  SER   L CB  1 
ATOM   2236 O  OG  . SER   B 2 77  ? -29.82100 6.73200  -3.70300  1.000 73.15762  ? 77  SER   L OG  1 
ATOM   2237 N  N   . ARG   B 2 78  ? -27.13200 5.56000  -0.48000  1.000 61.93591  ? 78  ARG   L N   1 
ATOM   2238 C  CA  . ARG   B 2 78  ? -26.45000 5.04900  0.70100   1.000 61.50827  ? 78  ARG   L CA  1 
ATOM   2239 C  C   . ARG   B 2 78  ? -25.02900 5.60100  0.73600   1.000 59.10378  ? 78  ARG   L C   1 
ATOM   2240 O  O   . ARG   B 2 78  ? -24.41700 5.84600  -0.30600  1.000 64.92419  ? 78  ARG   L O   1 
ATOM   2241 C  CB  . ARG   B 2 78  ? -26.42100 3.51600  0.70900   1.000 64.62429  ? 78  ARG   L CB  1 
ATOM   2242 C  CG  . ARG   B 2 78  ? -27.79400 2.86600  0.57300   1.000 70.74219  ? 78  ARG   L CG  1 
ATOM   2243 C  CD  . ARG   B 2 78  ? -27.74800 1.72100  -0.42500  1.000 73.49155  ? 78  ARG   L CD  1 
ATOM   2244 N  NE  . ARG   B 2 78  ? -27.99600 2.15500  -1.79800  1.000 76.53591  ? 78  ARG   L NE  1 
ATOM   2245 C  CZ  . ARG   B 2 78  ? -29.15800 2.61900  -2.25000  1.000 78.59438  ? 78  ARG   L CZ  1 
ATOM   2246 N  NH1 . ARG   B 2 78  ? -30.20700 2.71300  -1.44400  1.000 67.14719  ? 78  ARG   L NH1 1 
ATOM   2247 N  NH2 . ARG   B 2 78  ? -29.27200 2.98600  -3.51900  1.000 77.53539  ? 78  ARG   L NH2 1 
ATOM   2248 N  N   . LEU   B 2 79  ? -24.51200 5.82400  1.94100   1.000 51.94269  ? 79  LEU   L N   1 
ATOM   2249 C  CA  . LEU   B 2 79  ? -23.18700 6.40600  2.11200   1.000 50.72702  ? 79  LEU   L CA  1 
ATOM   2250 C  C   . LEU   B 2 79  ? -22.32600 5.46400  2.93700   1.000 51.72390  ? 79  LEU   L C   1 
ATOM   2251 O  O   . LEU   B 2 79  ? -22.62200 5.21400  4.11000   1.000 58.63143  ? 79  LEU   L O   1 
ATOM   2252 C  CB  . LEU   B 2 79  ? -23.26700 7.78100  2.77800   1.000 52.37146  ? 79  LEU   L CB  1 
ATOM   2253 C  CG  . LEU   B 2 79  ? -23.25200 8.97200  1.81700   1.000 53.96606  ? 79  LEU   L CG  1 
ATOM   2254 C  CD1 . LEU   B 2 79  ? -23.50600 10.26800 2.56500   1.000 49.58632  ? 79  LEU   L CD1 1 
ATOM   2255 C  CD2 . LEU   B 2 79  ? -21.94000 9.04500  1.05100   1.000 48.92649  ? 79  LEU   L CD2 1 
ATOM   2256 N  N   . GLU   B 2 80  ? -21.28400 4.95100  2.33100   1.000 53.87336  ? 80  GLU   L N   1 
ATOM   2257 C  CA  . GLU   B 2 80  ? -20.24300 4.21500  3.02400   1.000 57.35224  ? 80  GLU   L CA  1 
ATOM   2258 C  C   . GLU   B 2 80  ? -19.08400 5.15100  3.35600   1.000 60.54223  ? 80  GLU   L C   1 
ATOM   2259 O  O   . GLU   B 2 80  ? -18.88700 6.16600  2.67900   1.000 55.38600  ? 80  GLU   L O   1 
ATOM   2260 C  CB  . GLU   B 2 80  ? -19.74900 3.05300  2.16300   1.000 63.52957  ? 80  GLU   L CB  1 
ATOM   2261 C  CG  . GLU   B 2 80  ? -20.50500 1.74700  2.38600   1.000 74.55006  ? 80  GLU   L CG  1 
ATOM   2262 C  CD  . GLU   B 2 80  ? -21.86400 1.72500  1.70700   1.000 70.73163  ? 80  GLU   L CD  1 
ATOM   2263 O  OE1 . GLU   B 2 80  ? -21.93500 2.03900  0.50000   1.000 72.92001  ? 80  GLU   L OE1 1 
ATOM   2264 O  OE2 . GLU   B 2 80  ? -22.86100 1.39000  2.38200   1.000 63.85284  ? 80  GLU   L OE2 1 
ATOM   2265 N  N   . PRO   B 2 81  ? -18.30700 4.85600  4.40400   1.000 64.79747  ? 81  PRO   L N   1 
ATOM   2266 C  CA  . PRO   B 2 81  ? -17.21100 5.76600  4.78800   1.000 54.60846  ? 81  PRO   L CA  1 
ATOM   2267 C  C   . PRO   B 2 81  ? -16.14700 5.94100  3.71500   1.000 57.68652  ? 81  PRO   L C   1 
ATOM   2268 O  O   . PRO   B 2 81  ? -15.34700 6.88300  3.80500   1.000 55.67042  ? 81  PRO   L O   1 
ATOM   2269 C  CB  . PRO   B 2 81  ? -16.63100 5.10400  6.04600   1.000 46.80180  ? 81  PRO   L CB  1 
ATOM   2270 C  CG  . PRO   B 2 81  ? -17.75500 4.26800  6.58200   1.000 48.67842  ? 81  PRO   L CG  1 
ATOM   2271 C  CD  . PRO   B 2 81  ? -18.47700 3.75900  5.37200   1.000 56.39787  ? 81  PRO   L CD  1 
ATOM   2272 N  N   . ASP   B 2 82  ? -16.12200 5.06500  2.71300   1.000 61.61084  ? 82  ASP   L N   1 
ATOM   2273 C  CA  . ASP   B 2 82  ? -15.22600 5.10600  1.56900   1.000 56.51673  ? 82  ASP   L CA  1 
ATOM   2274 C  C   . ASP   B 2 82  ? -15.69100 6.14500  0.51900   1.000 58.38566  ? 82  ASP   L C   1 
ATOM   2275 O  O   . ASP   B 2 82  ? -15.20300 6.17200  -0.61700  1.000 60.95424  ? 82  ASP   L O   1 
ATOM   2276 C  CB  . ASP   B 2 82  ? -15.11600 3.67100  1.01300   1.000 63.66874  ? 82  ASP   L CB  1 
ATOM   2277 C  CG  . ASP   B 2 82  ? -14.50400 3.57600  -0.38200  1.000 69.36330  ? 82  ASP   L CG  1 
ATOM   2278 O  OD1 . ASP   B 2 82  ? -15.05400 2.80400  -1.19800  1.000 76.46094  ? 82  ASP   L OD1 1 
ATOM   2279 O  OD2 . ASP   B 2 82  ? -13.46400 4.21700  -0.65500  1.000 65.81684  ? 82  ASP   L OD2 1 
ATOM   2280 N  N   . ASP   B 2 83  ? -16.62400 7.02600  0.89200   1.000 56.74336  ? 83  ASP   L N   1 
ATOM   2281 C  CA  . ASP   B 2 83  ? -17.09500 8.09800  0.02000   1.000 51.85932  ? 83  ASP   L CA  1 
ATOM   2282 C  C   . ASP   B 2 83  ? -16.55700 9.47000  0.41900   1.000 50.75177  ? 83  ASP   L C   1 
ATOM   2283 O  O   . ASP   B 2 83  ? -16.99200 10.48500 -0.13900  1.000 51.27519  ? 83  ASP   L O   1 
ATOM   2284 C  CB  . ASP   B 2 83  ? -18.62500 8.11000  -0.01800  1.000 51.22017  ? 83  ASP   L CB  1 
ATOM   2285 C  CG  . ASP   B 2 83  ? -19.19600 6.84900  -0.63700  1.000 49.66236  ? 83  ASP   L CG  1 
ATOM   2286 O  OD1 . ASP   B 2 83  ? -18.46600 6.20400  -1.41700  1.000 48.94423  ? 83  ASP   L OD1 1 
ATOM   2287 O  OD2 . ASP   B 2 83  ? -20.36200 6.50200  -0.35300  1.000 53.68183  ? 83  ASP   L OD2 1 
ATOM   2288 N  N   . PHE   B 2 84  ? -15.62400 9.53000  1.37100   1.000 49.85908  ? 84  PHE   L N   1 
ATOM   2289 C  CA  . PHE   B 2 84  ? -14.89700 10.76600 1.62900   1.000 47.28812  ? 84  PHE   L CA  1 
ATOM   2290 C  C   . PHE   B 2 84  ? -14.03400 11.09400 0.41800   1.000 55.45534  ? 84  PHE   L C   1 
ATOM   2291 O  O   . PHE   B 2 84  ? -13.01500 10.43700 0.17600   1.000 56.81384  ? 84  PHE   L O   1 
ATOM   2292 C  CB  . PHE   B 2 84  ? -14.04100 10.65200 2.89200   1.000 45.73779  ? 84  PHE   L CB  1 
ATOM   2293 N  N   . ALA   B 2 85  ? -14.44500 12.09100 -0.35300  1.000 53.33408  ? 85  ALA   L N   1 
ATOM   2294 C  CA  . ALA   B 2 85  ? -13.76900 12.44800 -1.59400  1.000 42.39360  ? 85  ALA   L CA  1 
ATOM   2295 C  C   . ALA   B 2 85  ? -14.27100 13.81900 -2.02700  1.000 42.39842  ? 85  ALA   L C   1 
ATOM   2296 O  O   . ALA   B 2 85  ? -15.09400 14.44500 -1.35300  1.000 48.99098  ? 85  ALA   L O   1 
ATOM   2297 C  CB  . ALA   B 2 85  ? -14.00900 11.39800 -2.68200  1.000 43.60364  ? 85  ALA   L CB  1 
ATOM   2298 N  N   . ILE   B 2 86  ? -13.75500 14.28400 -3.16000  1.000 42.00932  ? 86  ILE   L N   1 
ATOM   2299 C  CA  . ILE   B 2 86  ? -14.24100 15.48300 -3.82700  1.000 32.65797  ? 86  ILE   L CA  1 
ATOM   2300 C  C   . ILE   B 2 86  ? -14.91100 15.05100 -5.12200  1.000 37.03116  ? 86  ILE   L C   1 
ATOM   2301 O  O   . ILE   B 2 86  ? -14.40400 14.17300 -5.83000  1.000 33.86826  ? 86  ILE   L O   1 
ATOM   2302 C  CB  . ILE   B 2 86  ? -13.10500 16.48800 -4.09600  1.000 35.15724  ? 86  ILE   L CB  1 
ATOM   2303 C  CG1 . ILE   B 2 86  ? -12.33400 16.77800 -2.80700  1.000 39.33805  ? 86  ILE   L CG1 1 
ATOM   2304 C  CG2 . ILE   B 2 86  ? -13.65700 17.77600 -4.68800  1.000 33.11542  ? 86  ILE   L CG2 1 
ATOM   2305 C  CD1 . ILE   B 2 86  ? -11.17700 17.73500 -2.99100  1.000 42.46094  ? 86  ILE   L CD1 1 
ATOM   2306 N  N   . TYR   B 2 87  ? -16.05500 15.65800 -5.42600  1.000 40.21736  ? 87  TYR   L N   1 
ATOM   2307 C  CA  . TYR   B 2 87  ? -16.87500 15.26200 -6.56400  1.000 33.73609  ? 87  TYR   L CA  1 
ATOM   2308 C  C   . TYR   B 2 87  ? -17.00600 16.43800 -7.52000  1.000 31.50772  ? 87  TYR   L C   1 
ATOM   2309 O  O   . TYR   B 2 87  ? -17.53300 17.49100 -7.14700  1.000 36.39677  ? 87  TYR   L O   1 
ATOM   2310 C  CB  . TYR   B 2 87  ? -18.24900 14.77800 -6.09900  1.000 34.14697  ? 87  TYR   L CB  1 
ATOM   2311 C  CG  . TYR   B 2 87  ? -18.19400 13.52300 -5.25400  1.000 38.00277  ? 87  TYR   L CG  1 
ATOM   2312 C  CD1 . TYR   B 2 87  ? -17.79700 13.57300 -3.92200  1.000 39.97529  ? 87  TYR   L CD1 1 
ATOM   2313 C  CD2 . TYR   B 2 87  ? -18.53500 12.28800 -5.78800  1.000 35.66858  ? 87  TYR   L CD2 1 
ATOM   2314 C  CE1 . TYR   B 2 87  ? -17.74100 12.42800 -3.14900  1.000 44.07074  ? 87  TYR   L CE1 1 
ATOM   2315 C  CE2 . TYR   B 2 87  ? -18.48300 11.13900 -5.02100  1.000 38.72683  ? 87  TYR   L CE2 1 
ATOM   2316 C  CZ  . TYR   B 2 87  ? -18.08600 11.21500 -3.70300  1.000 43.83013  ? 87  TYR   L CZ  1 
ATOM   2317 O  OH  . TYR   B 2 87  ? -18.03300 10.07200 -2.93700  1.000 42.05358  ? 87  TYR   L OH  1 
ATOM   2318 N  N   . TYR   B 2 88  ? -16.53300 16.25200 -8.75000  1.000 33.09760  ? 88  TYR   L N   1 
ATOM   2319 C  CA  . TYR   B 2 88  ? -16.52800 17.28800 -9.77100  1.000 30.28206  ? 88  TYR   L CA  1 
ATOM   2320 C  C   . TYR   B 2 88  ? -17.59300 17.00400 -10.82000 1.000 30.81523  ? 88  TYR   L C   1 
ATOM   2321 O  O   . TYR   B 2 88  ? -17.81700 15.84900 -11.19300 1.000 31.25284  ? 88  TYR   L O   1 
ATOM   2322 C  CB  . TYR   B 2 88  ? -15.16500 17.37300 -10.46400 1.000 28.06254  ? 88  TYR   L CB  1 
ATOM   2323 C  CG  . TYR   B 2 88  ? -14.01600 17.77200 -9.57100  1.000 30.91429  ? 88  TYR   L CG  1 
ATOM   2324 C  CD1 . TYR   B 2 88  ? -13.81100 19.10000 -9.22400  1.000 34.83317  ? 88  TYR   L CD1 1 
ATOM   2325 C  CD2 . TYR   B 2 88  ? -13.12200 16.82400 -9.09100  1.000 30.59176  ? 88  TYR   L CD2 1 
ATOM   2326 C  CE1 . TYR   B 2 88  ? -12.75600 19.47300 -8.41400  1.000 39.94409  ? 88  TYR   L CE1 1 
ATOM   2327 C  CE2 . TYR   B 2 88  ? -12.06200 17.18700 -8.28000  1.000 33.67629  ? 88  TYR   L CE2 1 
ATOM   2328 C  CZ  . TYR   B 2 88  ? -11.88400 18.51400 -7.94400  1.000 37.02168  ? 88  TYR   L CZ  1 
ATOM   2329 O  OH  . TYR   B 2 88  ? -10.83200 18.88300 -7.13800  1.000 43.58839  ? 88  TYR   L OH  1 
ATOM   2330 N  N   . CYS   B 2 89  ? -18.24100 18.06100 -11.30000 1.000 32.91108  ? 89  CYS   L N   1 
ATOM   2331 C  CA  . CYS   B 2 89  ? -19.06200 17.98100 -12.49800 1.000 37.00833  ? 89  CYS   L CA  1 
ATOM   2332 C  C   . CYS   B 2 89  ? -18.27500 18.53900 -13.67700 1.000 34.16417  ? 89  CYS   L C   1 
ATOM   2333 O  O   . CYS   B 2 89  ? -17.39600 19.38800 -13.51200 1.000 36.76118  ? 89  CYS   L O   1 
ATOM   2334 C  CB  . CYS   B 2 89  ? -20.38200 18.74400 -12.33600 1.000 37.06946  ? 89  CYS   L CB  1 
ATOM   2335 S  SG  . CYS   B 2 89  ? -20.21500 20.52900 -12.10900 1.000 51.20552  ? 89  CYS   L SG  1 
ATOM   2336 N  N   . GLN   B 2 90  ? -18.58700 18.04200 -14.87100 1.000 28.45097  ? 90  GLN   L N   1 
ATOM   2337 C  CA  . GLN   B 2 90  ? -17.89600 18.48800 -16.07400 1.000 29.72582  ? 90  GLN   L CA  1 
ATOM   2338 C  C   . GLN   B 2 90  ? -18.84800 18.43900 -17.25700 1.000 34.30822  ? 90  GLN   L C   1 
ATOM   2339 O  O   . GLN   B 2 90  ? -19.50500 17.41900 -17.48600 1.000 34.57263  ? 90  GLN   L O   1 
ATOM   2340 C  CB  . GLN   B 2 90  ? -16.66100 17.62700 -16.35900 1.000 31.09851  ? 90  GLN   L CB  1 
ATOM   2341 C  CG  . GLN   B 2 90  ? -15.92300 18.03300 -17.62500 1.000 35.82419  ? 90  GLN   L CG  1 
ATOM   2342 C  CD  . GLN   B 2 90  ? -15.58600 16.85800 -18.51800 1.000 32.50146  ? 90  GLN   L CD  1 
ATOM   2343 O  OE1 . GLN   B 2 90  ? -15.29500 15.76300 -18.03900 1.000 37.30441  ? 90  GLN   L OE1 1 
ATOM   2344 N  NE2 . GLN   B 2 90  ? -15.62500 17.07900 -19.82700 1.000 36.92044  ? 90  GLN   L NE2 1 
ATOM   2345 N  N   . GLN   B 2 91  ? -18.91200 19.53600 -18.00300 1.000 34.96982  ? 91  GLN   L N   1 
ATOM   2346 C  CA  . GLN   B 2 91  ? -19.70600 19.60900 -19.21800 1.000 33.95039  ? 91  GLN   L CA  1 
ATOM   2347 C  C   . GLN   B 2 91  ? -18.82100 19.38000 -20.43700 1.000 35.78075  ? 91  GLN   L C   1 
ATOM   2348 O  O   . GLN   B 2 91  ? -17.61600 19.64100 -20.41200 1.000 33.68498  ? 91  GLN   L O   1 
ATOM   2349 C  CB  . GLN   B 2 91  ? -20.41400 20.96100 -19.33400 1.000 38.33390  ? 91  GLN   L CB  1 
ATOM   2350 C  CG  . GLN   B 2 91  ? -19.48000 22.14000 -19.55800 1.000 34.85148  ? 91  GLN   L CG  1 
ATOM   2351 C  CD  . GLN   B 2 91  ? -19.33700 22.51200 -21.02400 1.000 42.47227  ? 91  GLN   L CD  1 
ATOM   2352 O  OE1 . GLN   B 2 91  ? -20.17800 22.16000 -21.85200 1.000 42.86264  ? 91  GLN   L OE1 1 
ATOM   2353 N  NE2 . GLN   B 2 91  ? -18.26300 23.22200 -21.35200 1.000 46.64423  ? 91  GLN   L NE2 1 
ATOM   2354 N  N   . TYR   B 2 92  ? -19.43500 18.88200 -21.51100 1.000 37.76354  ? 92  TYR   L N   1 
ATOM   2355 C  CA  . TYR   B 2 92  ? -18.72600 18.71200 -22.77400 1.000 40.38791  ? 92  TYR   L CA  1 
ATOM   2356 C  C   . TYR   B 2 92  ? -19.67300 18.95700 -23.94400 1.000 44.46496  ? 92  TYR   L C   1 
ATOM   2357 O  O   . TYR   B 2 92  ? -19.68400 18.20500 -24.92400 1.000 51.51490  ? 92  TYR   L O   1 
ATOM   2358 C  CB  . TYR   B 2 92  ? -18.06200 17.33200 -22.87600 1.000 41.84920  ? 92  TYR   L CB  1 
ATOM   2359 C  CG  . TYR   B 2 92  ? -18.94100 16.13400 -22.57200 1.000 40.92113  ? 92  TYR   L CG  1 
ATOM   2360 C  CD1 . TYR   B 2 92  ? -19.37000 15.86600 -21.27800 1.000 39.03725  ? 92  TYR   L CD1 1 
ATOM   2361 C  CD2 . TYR   B 2 92  ? -19.30800 15.24700 -23.57700 1.000 39.83810  ? 92  TYR   L CD2 1 
ATOM   2362 C  CE1 . TYR   B 2 92  ? -20.15900 14.76600 -20.99800 1.000 39.84412  ? 92  TYR   L CE1 1 
ATOM   2363 C  CE2 . TYR   B 2 92  ? -20.09600 14.14300 -23.30600 1.000 43.63144  ? 92  TYR   L CE2 1 
ATOM   2364 C  CZ  . TYR   B 2 92  ? -20.51900 13.90800 -22.01300 1.000 45.65062  ? 92  TYR   L CZ  1 
ATOM   2365 O  OH  . TYR   B 2 92  ? -21.30400 12.81300 -21.73000 1.000 43.48932  ? 92  TYR   L OH  1 
ATOM   2366 N  N   . GLY   B 2 93  ? -20.46700 20.02100 -23.85500 1.000 42.82829  ? 93  GLY   L N   1 
ATOM   2367 C  CA  . GLY   B 2 93  ? -21.38700 20.37100 -24.91700 1.000 46.72912  ? 93  GLY   L CA  1 
ATOM   2368 C  C   . GLY   B 2 93  ? -20.92600 21.56000 -25.73400 1.000 58.91304  ? 93  GLY   L C   1 
ATOM   2369 O  O   . GLY   B 2 93  ? -21.16200 21.61400 -26.94500 1.000 65.22936  ? 93  GLY   L O   1 
ATOM   2370 N  N   . SER   B 2 94  ? -20.26600 22.51600 -25.08500 1.000 64.45802  ? 94  SER   L N   1 
ATOM   2371 C  CA  . SER   B 2 94  ? -19.79800 23.73200 -25.74600 1.000 66.03273  ? 94  SER   L CA  1 
ATOM   2372 C  C   . SER   B 2 94  ? -18.88700 23.43400 -26.93400 1.000 69.53121  ? 94  SER   L C   1 
ATOM   2373 O  O   . SER   B 2 94  ? -18.17400 24.31500 -27.41700 1.000 69.37018  ? 94  SER   L O   1 
ATOM   2374 C  CB  . SER   B 2 94  ? -19.06100 24.62900 -24.74900 1.000 56.88118  ? 94  SER   L CB  1 
ATOM   2375 O  OG  . SER   B 2 94  ? -18.03100 25.35900 -25.39300 1.000 58.52656  ? 94  SER   L OG  1 
ATOM   2376 N  N   . PRO   B 2 97  ? -14.93100 24.78000 -25.51000 1.000 52.15571  ? 97  PRO   L N   1 
ATOM   2377 C  CA  . PRO   B 2 97  ? -14.04900 24.19300 -24.49600 1.000 51.47620  ? 97  PRO   L CA  1 
ATOM   2378 C  C   . PRO   B 2 97  ? -14.80900 23.45400 -23.39700 1.000 51.05759  ? 97  PRO   L C   1 
ATOM   2379 O  O   . PRO   B 2 97  ? -15.89400 23.88000 -23.00100 1.000 56.93342  ? 97  PRO   L O   1 
ATOM   2380 C  CB  . PRO   B 2 97  ? -13.31900 25.41000 -23.92300 1.000 39.59901  ? 97  PRO   L CB  1 
ATOM   2381 C  CG  . PRO   B 2 97  ? -14.25700 26.54300 -24.14300 1.000 42.35494  ? 97  PRO   L CG  1 
ATOM   2382 C  CD  . PRO   B 2 97  ? -14.94300 26.25200 -25.44700 1.000 53.51209  ? 97  PRO   L CD  1 
ATOM   2383 N  N   . VAL   B 2 98  ? -14.24000 22.35000 -22.91800 1.000 42.84221  ? 98  VAL   L N   1 
ATOM   2384 C  CA  . VAL   B 2 98  ? -14.82300 21.60000 -21.81100 1.000 42.05252  ? 98  VAL   L CA  1 
ATOM   2385 C  C   . VAL   B 2 98  ? -14.41900 22.26000 -20.49900 1.000 42.55602  ? 98  VAL   L C   1 
ATOM   2386 O  O   . VAL   B 2 98  ? -13.33000 22.83300 -20.38000 1.000 45.34891  ? 98  VAL   L O   1 
ATOM   2387 C  CB  . VAL   B 2 98  ? -14.37600 20.12600 -21.86500 1.000 42.54481  ? 98  VAL   L CB  1 
ATOM   2388 C  CG1 . VAL   B 2 98  ? -15.13400 19.38700 -22.95100 1.000 39.65547  ? 98  VAL   L CG1 1 
ATOM   2389 C  CG2 . VAL   B 2 98  ? -12.88300 20.04200 -22.11500 1.000 38.56796  ? 98  VAL   L CG2 1 
ATOM   2390 N  N   . THR   B 2 99  ? -15.30100 22.20000 -19.50200 1.000 42.71817  ? 99  THR   L N   1 
ATOM   2391 C  CA  . THR   B 2 99  ? -15.05900 22.88600 -18.23900 1.000 35.45871  ? 99  THR   L CA  1 
ATOM   2392 C  C   . THR   B 2 99  ? -15.44800 21.99400 -17.07000 1.000 35.50095  ? 99  THR   L C   1 
ATOM   2393 O  O   . THR   B 2 99  ? -16.35800 21.16800 -17.17100 1.000 30.73322  ? 99  THR   L O   1 
ATOM   2394 C  CB  . THR   B 2 99  ? -15.83100 24.21400 -18.14800 1.000 40.00971  ? 99  THR   L CB  1 
ATOM   2395 O  OG1 . THR   B 2 99  ? -17.21200 23.99200 -18.45800 1.000 45.48700  ? 99  THR   L OG1 1 
ATOM   2396 C  CG2 . THR   B 2 99  ? -15.25400 25.23900 -19.11100 1.000 43.25437  ? 99  THR   L CG2 1 
ATOM   2397 N  N   . PHE   B 2 100 ? -14.74500 22.17900 -15.95600 1.000 40.02860  ? 100 PHE   L N   1 
ATOM   2398 C  CA  . PHE   B 2 100 ? -15.00800 21.47300 -14.71300 1.000 39.78506  ? 100 PHE   L CA  1 
ATOM   2399 C  C   . PHE   B 2 100 ? -15.53000 22.44300 -13.66300 1.000 36.45378  ? 100 PHE   L C   1 
ATOM   2400 O  O   . PHE   B 2 100 ? -15.20900 23.63400 -13.68100 1.000 46.71232  ? 100 PHE   L O   1 
ATOM   2401 C  CB  . PHE   B 2 100 ? -13.74200 20.80100 -14.16700 1.000 39.63975  ? 100 PHE   L CB  1 
ATOM   2402 C  CG  . PHE   B 2 100 ? -13.29400 19.60300 -14.94900 1.000 39.33483  ? 100 PHE   L CG  1 
ATOM   2403 C  CD1 . PHE   B 2 100 ? -12.47600 19.75100 -16.05600 1.000 34.05558  ? 100 PHE   L CD1 1 
ATOM   2404 C  CD2 . PHE   B 2 100 ? -13.66400 18.32600 -14.56000 1.000 40.01962  ? 100 PHE   L CD2 1 
ATOM   2405 C  CE1 . PHE   B 2 100 ? -12.05100 18.65000 -16.77300 1.000 35.64745  ? 100 PHE   L CE1 1 
ATOM   2406 C  CE2 . PHE   B 2 100 ? -13.24200 17.22000 -15.27300 1.000 31.58133  ? 100 PHE   L CE2 1 
ATOM   2407 C  CZ  . PHE   B 2 100 ? -12.43400 17.38300 -16.38100 1.000 35.06009  ? 100 PHE   L CZ  1 
ATOM   2408 N  N   . GLY   B 2 101 ? -16.33300 21.91900 -12.74600 1.000 32.38052  ? 101 GLY   L N   1 
ATOM   2409 C  CA  . GLY   B 2 101 ? -16.61700 22.63700 -11.52500 1.000 32.98717  ? 101 GLY   L CA  1 
ATOM   2410 C  C   . GLY   B 2 101 ? -15.44700 22.54800 -10.56400 1.000 39.45935  ? 101 GLY   L C   1 
ATOM   2411 O  O   . GLY   B 2 101 ? -14.47300 21.82500 -10.77800 1.000 38.45816  ? 101 GLY   L O   1 
ATOM   2412 N  N   . HIS   B 2 102 ? -15.53800 23.31100 -9.47900  1.000 41.71848  ? 102 HIS   L N   1 
ATOM   2413 C  CA  . HIS   B 2 102 ? -14.49600 23.27600 -8.46400  1.000 37.03529  ? 102 HIS   L CA  1 
ATOM   2414 C  C   . HIS   B 2 102 ? -14.70600 22.16900 -7.44100  1.000 38.45836  ? 102 HIS   L C   1 
ATOM   2415 O  O   . HIS   B 2 102 ? -13.81500 21.92700 -6.61900  1.000 40.87146  ? 102 HIS   L O   1 
ATOM   2416 C  CB  . HIS   B 2 102 ? -14.39400 24.63400 -7.76500  1.000 47.56689  ? 102 HIS   L CB  1 
ATOM   2417 C  CG  . HIS   B 2 102 ? -13.95000 25.74000 -8.67200  1.000 60.89558  ? 102 HIS   L CG  1 
ATOM   2418 N  ND1 . HIS   B 2 102 ? -13.91100 27.06000 -8.27900  1.000 60.23463  ? 102 HIS   L ND1 1 
ATOM   2419 C  CD2 . HIS   B 2 102 ? -13.53000 25.71900 -9.96000  1.000 53.31515  ? 102 HIS   L CD2 1 
ATOM   2420 C  CE1 . HIS   B 2 102 ? -13.48400 27.80400 -9.28300  1.000 61.87046  ? 102 HIS   L CE1 1 
ATOM   2421 N  NE2 . HIS   B 2 102 ? -13.24600 27.01500 -10.31500 1.000 58.68412  ? 102 HIS   L NE2 1 
ATOM   2422 N  N   . GLY   B 2 103 ? -15.84800 21.49600 -7.47200  1.000 35.86510  ? 103 GLY   L N   1 
ATOM   2423 C  CA  . GLY   B 2 103 ? -16.04000 20.28900 -6.70000  1.000 34.61817  ? 103 GLY   L CA  1 
ATOM   2424 C  C   . GLY   B 2 103 ? -16.82100 20.52600 -5.41800  1.000 41.27919  ? 103 GLY   L C   1 
ATOM   2425 O  O   . GLY   B 2 103 ? -16.98600 21.65300 -4.94400  1.000 42.26705  ? 103 GLY   L O   1 
ATOM   2426 N  N   . THR   B 2 104 ? -17.31000 19.42400 -4.85100  1.000 38.99853  ? 104 THR   L N   1 
ATOM   2427 C  CA  . THR   B 2 104 ? -17.99200 19.42100 -3.56000  1.000 36.36654  ? 104 THR   L CA  1 
ATOM   2428 C  C   . THR   B 2 104 ? -17.30100 18.40300 -2.66500  1.000 34.18860  ? 104 THR   L C   1 
ATOM   2429 O  O   . THR   B 2 104 ? -17.34500 17.20000 -2.94100  1.000 37.12850  ? 104 THR   L O   1 
ATOM   2430 C  CB  . THR   B 2 104 ? -19.47600 19.08600 -3.71200  1.000 37.27166  ? 104 THR   L CB  1 
ATOM   2431 O  OG1 . THR   B 2 104 ? -20.13800 20.14000 -4.42200  1.000 35.72664  ? 104 THR   L OG1 1 
ATOM   2432 C  CG2 . THR   B 2 104 ? -20.12100 18.90400 -2.34600  1.000 34.51577  ? 104 THR   L CG2 1 
ATOM   2433 N  N   . LYS   B 2 105 ? -16.64800 18.88100 -1.61000  1.000 40.18142  ? 105 LYS   L N   1 
ATOM   2434 C  CA  . LYS   B 2 105 ? -16.05500 17.97600 -0.63800  1.000 38.50987  ? 105 LYS   L CA  1 
ATOM   2435 C  C   . LYS   B 2 105 ? -17.15000 17.24900 0.13200   1.000 41.92646  ? 105 LYS   L C   1 
ATOM   2436 O  O   . LYS   B 2 105 ? -18.17900 17.83400 0.48100   1.000 37.64147  ? 105 LYS   L O   1 
ATOM   2437 C  CB  . LYS   B 2 105 ? -15.15400 18.74200 0.32800   1.000 40.77162  ? 105 LYS   L CB  1 
ATOM   2438 C  CG  . LYS   B 2 105 ? -13.78400 19.08100 -0.23100  1.000 48.83958  ? 105 LYS   L CG  1 
ATOM   2439 C  CD  . LYS   B 2 105 ? -12.73900 19.09500 0.87300   1.000 63.12718  ? 105 LYS   L CD  1 
ATOM   2440 C  CE  . LYS   B 2 105 ? -11.46800 19.79900 0.42900   1.000 63.16204  ? 105 LYS   L CE  1 
ATOM   2441 N  NZ  . LYS   B 2 105 ? -11.69400 21.25500 0.20900   1.000 57.02839  ? 105 LYS   L NZ  1 
ATOM   2442 N  N   . VAL   B 2 106 ? -16.92700 15.96300 0.39100   1.000 38.40974  ? 106 VAL   L N   1 
ATOM   2443 C  CA  . VAL   B 2 106 ? -17.88000 15.12800 1.11500   1.000 34.60519  ? 106 VAL   L CA  1 
ATOM   2444 C  C   . VAL   B 2 106 ? -17.14700 14.53100 2.31000   1.000 37.10836  ? 106 VAL   L C   1 
ATOM   2445 O  O   . VAL   B 2 106 ? -16.36600 13.58500 2.16200   1.000 47.18427  ? 106 VAL   L O   1 
ATOM   2446 C  CB  . VAL   B 2 106 ? -18.49100 14.03000 0.23800   1.000 37.46634  ? 106 VAL   L CB  1 
ATOM   2447 C  CG1 . VAL   B 2 106 ? -19.34800 13.09900 1.08400   1.000 34.40245  ? 106 VAL   L CG1 1 
ATOM   2448 C  CG2 . VAL   B 2 106 ? -19.32100 14.65000 -0.87500  1.000 39.54274  ? 106 VAL   L CG2 1 
ATOM   2449 N  N   . GLU   B 2 107 ? -17.39000 15.08400 3.49300   1.000 38.53657  ? 107 GLU   L N   1 
ATOM   2450 C  CA  . GLU   B 2 107 ? -16.90700 14.48500 4.72600   1.000 40.65676  ? 107 GLU   L CA  1 
ATOM   2451 C  C   . GLU   B 2 107 ? -17.88600 13.41800 5.20300   1.000 40.20055  ? 107 GLU   L C   1 
ATOM   2452 O  O   . GLU   B 2 107 ? -19.09200 13.49600 4.95200   1.000 37.92785  ? 107 GLU   L O   1 
ATOM   2453 C  CB  . GLU   B 2 107 ? -16.72600 15.55300 5.80800   1.000 43.88766  ? 107 GLU   L CB  1 
ATOM   2454 C  CG  . GLU   B 2 107 ? -16.07400 15.05400 7.08900   1.000 46.20286  ? 107 GLU   L CG  1 
ATOM   2455 C  CD  . GLU   B 2 107 ? -16.08000 16.09300 8.19600   1.000 51.93351  ? 107 GLU   L CD  1 
ATOM   2456 O  OE1 . GLU   B 2 107 ? -17.15500 16.66400 8.46800   1.000 56.25192  ? 107 GLU   L OE1 1 
ATOM   2457 O  OE2 . GLU   B 2 107 ? -15.01000 16.33700 8.79400   1.000 52.33458  ? 107 GLU   L OE2 1 
ATOM   2458 N  N   . ILE   B 2 108 ? -17.35400 12.40700 5.88200   1.000 37.15658  ? 108 ILE   L N   1 
ATOM   2459 C  CA  . ILE   B 2 108 ? -18.16700 11.36900 6.50500   1.000 39.57700  ? 108 ILE   L CA  1 
ATOM   2460 C  C   . ILE   B 2 108 ? -18.23900 11.66100 7.99800   1.000 45.81804  ? 108 ILE   L C   1 
ATOM   2461 O  O   . ILE   B 2 108 ? -17.20700 11.75700 8.67300   1.000 43.97721  ? 108 ILE   L O   1 
ATOM   2462 C  CB  . ILE   B 2 108 ? -17.60100 9.96700  6.23100   1.000 46.78214  ? 108 ILE   L CB  1 
ATOM   2463 C  CG1 . ILE   B 2 108 ? -17.96200 9.52500  4.81100   1.000 47.86646  ? 108 ILE   L CG1 1 
ATOM   2464 C  CG2 . ILE   B 2 108 ? -18.13400 8.96800  7.24600   1.000 42.43647  ? 108 ILE   L CG2 1 
ATOM   2465 C  CD1 . ILE   B 2 108 ? -19.45300 9.51500  4.53500   1.000 46.67919  ? 108 ILE   L CD1 1 
ATOM   2466 N  N   . LYS   B 2 109 ? -19.45800 11.80700 8.50900   1.000 48.29724  ? 109 LYS   L N   1 
ATOM   2467 C  CA  . LYS   B 2 109 ? -19.67100 12.18200 9.89800   1.000 41.19361  ? 109 LYS   L CA  1 
ATOM   2468 C  C   . LYS   B 2 109 ? -19.57500 10.96400 10.80900  1.000 47.77204  ? 109 LYS   L C   1 
ATOM   2469 O  O   . LYS   B 2 109 ? -19.92300 9.84300  10.42700  1.000 53.12436  ? 109 LYS   L O   1 
ATOM   2470 C  CB  . LYS   B 2 109 ? -21.03600 12.85300 10.06100  1.000 42.43940  ? 109 LYS   L CB  1 
ATOM   2471 C  CG  . LYS   B 2 109 ? -21.24400 13.56800 11.38700  1.000 48.52613  ? 109 LYS   L CG  1 
ATOM   2472 C  CD  . LYS   B 2 109 ? -22.46500 14.47600 11.32900  1.000 53.01470  ? 109 LYS   L CD  1 
ATOM   2473 C  CE  . LYS   B 2 109 ? -22.23900 15.64000 10.37500  1.000 51.09042  ? 109 LYS   L CE  1 
ATOM   2474 N  NZ  . LYS   B 2 109 ? -23.47500 16.44100 10.15300  1.000 44.86811  ? 109 LYS   L NZ  1 
ATOM   2475 N  N   . ARG   B 2 110 ? -19.09500 11.19700 12.02800  1.000 46.28485  ? 110 ARG   L N   1 
ATOM   2476 C  CA  . ARG   B 2 110 ? -18.97800 10.14500 13.02700  1.000 42.50191  ? 110 ARG   L CA  1 
ATOM   2477 C  C   . ARG   B 2 110 ? -19.04700 10.77900 14.41100  1.000 42.69444  ? 110 ARG   L C   1 
ATOM   2478 O  O   . ARG   B 2 110 ? -19.15400 12.00100 14.55400  1.000 40.89336  ? 110 ARG   L O   1 
ATOM   2479 C  CB  . ARG   B 2 110 ? -17.68700 9.34500  12.83300  1.000 40.55043  ? 110 ARG   L CB  1 
ATOM   2480 C  CG  . ARG   B 2 110 ? -16.44800 10.20300 12.67100  1.000 43.81414  ? 110 ARG   L CG  1 
ATOM   2481 C  CD  . ARG   B 2 110 ? -15.23000 9.51900  13.26400  1.000 42.95988  ? 110 ARG   L CD  1 
ATOM   2482 N  NE  . ARG   B 2 110 ? -15.35900 9.32500  14.70400  1.000 44.20767  ? 110 ARG   L NE  1 
ATOM   2483 C  CZ  . ARG   B 2 110 ? -14.83600 8.29900  15.36900  1.000 46.03320  ? 110 ARG   L CZ  1 
ATOM   2484 N  NH1 . ARG   B 2 110 ? -14.14800 7.36800  14.72100  1.000 44.47118  ? 110 ARG   L NH1 1 
ATOM   2485 N  NH2 . ARG   B 2 110 ? -15.00200 8.20300  16.68100  1.000 38.36830  ? 110 ARG   L NH2 1 
ATOM   2486 N  N   . THR   B 2 111 ? -18.99000 9.93400  15.43700  1.000 45.70546  ? 111 THR   L N   1 
ATOM   2487 C  CA  . THR   B 2 111 ? -19.09800 10.41100 16.80700  1.000 48.52500  ? 111 THR   L CA  1 
ATOM   2488 C  C   . THR   B 2 111 ? -17.83400 11.15400 17.22300  1.000 41.31070  ? 111 THR   L C   1 
ATOM   2489 O  O   . THR   B 2 111 ? -16.73500 10.88500 16.73000  1.000 39.51841  ? 111 THR   L O   1 
ATOM   2490 C  CB  . THR   B 2 111 ? -19.35900 9.24600  17.76100  1.000 43.83770  ? 111 THR   L CB  1 
ATOM   2491 O  OG1 . THR   B 2 111 ? -18.16600 8.46400  17.90100  1.000 49.77948  ? 111 THR   L OG1 1 
ATOM   2492 C  CG2 . THR   B 2 111 ? -20.47500 8.36400  17.22500  1.000 43.49345  ? 111 THR   L CG2 1 
ATOM   2493 N  N   . VAL   B 2 112 ? -18.00500 12.10100 18.14900  1.000 39.90986  ? 112 VAL   L N   1 
ATOM   2494 C  CA  . VAL   B 2 112 ? -16.90700 12.97000 18.55100  1.000 38.82043  ? 112 VAL   L CA  1 
ATOM   2495 C  C   . VAL   B 2 112 ? -15.79200 12.14300 19.17100  1.000 42.58787  ? 112 VAL   L C   1 
ATOM   2496 O  O   . VAL   B 2 112 ? -16.03600 11.26700 20.01100  1.000 51.19262  ? 112 VAL   L O   1 
ATOM   2497 C  CB  . VAL   B 2 112 ? -17.41100 14.04600 19.52300  1.000 39.24549  ? 112 VAL   L CB  1 
ATOM   2498 C  CG1 . VAL   B 2 112 ? -16.30800 15.03900 19.82900  1.000 45.23908  ? 112 VAL   L CG1 1 
ATOM   2499 C  CG2 . VAL   B 2 112 ? -18.62600 14.75400 18.94400  1.000 40.20867  ? 112 VAL   L CG2 1 
ATOM   2500 N  N   . ALA   B 2 113 ? -14.55700 12.41700 18.75600  1.000 41.19994  ? 113 ALA   L N   1 
ATOM   2501 C  CA  . ALA   B 2 113 ? -13.38500 11.70900 19.25000  1.000 39.27847  ? 113 ALA   L CA  1 
ATOM   2502 C  C   . ALA   B 2 113 ? -12.30700 12.71900 19.60800  1.000 42.03649  ? 113 ALA   L C   1 
ATOM   2503 O  O   . ALA   B 2 113 ? -11.96000 13.57800 18.79200  1.000 40.71631  ? 113 ALA   L O   1 
ATOM   2504 C  CB  . ALA   B 2 113 ? -12.85700 10.71400 18.21200  1.000 37.96723  ? 113 ALA   L CB  1 
ATOM   2505 N  N   . ALA   B 2 114 ? -11.78500 12.61300 20.82500  1.000 45.18378  ? 114 ALA   L N   1 
ATOM   2506 C  CA  . ALA   B 2 114 ? -10.74000 13.51300 21.27700  1.000 45.53677  ? 114 ALA   L CA  1 
ATOM   2507 C  C   . ALA   B 2 114 ? -9.37300  13.02900 20.80100  1.000 41.42148  ? 114 ALA   L C   1 
ATOM   2508 O  O   . ALA   B 2 114 ? -9.13200  11.82300 20.69600  1.000 41.26316  ? 114 ALA   L O   1 
ATOM   2509 C  CB  . ALA   B 2 114 ? -10.74400 13.61800 22.79700  1.000 48.08852  ? 114 ALA   L CB  1 
ATOM   2510 N  N   . PRO   B 2 115 ? -8.46600  13.95100 20.50100  1.000 38.70979  ? 115 PRO   L N   1 
ATOM   2511 C  CA  . PRO   B 2 115 ? -7.12200  13.55200 20.08500  1.000 36.90367  ? 115 PRO   L CA  1 
ATOM   2512 C  C   . PRO   B 2 115 ? -6.23100  13.23100 21.27300  1.000 38.89894  ? 115 PRO   L C   1 
ATOM   2513 O  O   . PRO   B 2 115 ? -6.35800  13.80600 22.35700  1.000 41.75166  ? 115 PRO   L O   1 
ATOM   2514 C  CB  . PRO   B 2 115 ? -6.60800  14.78800 19.33900  1.000 38.33445  ? 115 PRO   L CB  1 
ATOM   2515 C  CG  . PRO   B 2 115 ? -7.29700  15.92800 20.02200  1.000 42.32850  ? 115 PRO   L CG  1 
ATOM   2516 C  CD  . PRO   B 2 115 ? -8.65300  15.41200 20.44900  1.000 40.90461  ? 115 PRO   L CD  1 
ATOM   2517 N  N   . SER   B 2 116 ? -5.32600  12.28400 21.05300  1.000 33.75255  ? 116 SER   L N   1 
ATOM   2518 C  CA  . SER   B 2 116 ? -4.18300  12.09400 21.93200  1.000 31.57808  ? 116 SER   L CA  1 
ATOM   2519 C  C   . SER   B 2 116 ? -3.05000  12.97200 21.41700  1.000 35.95826  ? 116 SER   L C   1 
ATOM   2520 O  O   . SER   B 2 116 ? -2.75800  12.97500 20.21600  1.000 38.29850  ? 116 SER   L O   1 
ATOM   2521 C  CB  . SER   B 2 116 ? -3.75900  10.62600 21.97800  1.000 40.51870  ? 116 SER   L CB  1 
ATOM   2522 O  OG  . SER   B 2 116 ? -3.42900  10.14300 20.68600  1.000 41.49504  ? 116 SER   L OG  1 
ATOM   2523 N  N   . VAL   B 2 117 ? -2.43200  13.73000 22.31600  1.000 39.76334  ? 117 VAL   L N   1 
ATOM   2524 C  CA  . VAL   B 2 117 ? -1.47600  14.76500 21.94300  1.000 36.32289  ? 117 VAL   L CA  1 
ATOM   2525 C  C   . VAL   B 2 117 ? -0.07000  14.30900 22.30200  1.000 36.35578  ? 117 VAL   L C   1 
ATOM   2526 O  O   . VAL   B 2 117 ? 0.16400   13.76700 23.38900  1.000 38.19054  ? 117 VAL   L O   1 
ATOM   2527 C  CB  . VAL   B 2 117 ? -1.81100  16.10700 22.62000  1.000 35.65938  ? 117 VAL   L CB  1 
ATOM   2528 C  CG1 . VAL   B 2 117 ? -0.94000  17.21800 22.05600  1.000 34.82368  ? 117 VAL   L CG1 1 
ATOM   2529 C  CG2 . VAL   B 2 117 ? -3.28700  16.43400 22.43800  1.000 28.65475  ? 117 VAL   L CG2 1 
ATOM   2530 N  N   . PHE   B 2 118 ? 0.86300   14.52700 21.37900  1.000 33.93397  ? 118 PHE   L N   1 
ATOM   2531 C  CA  . PHE   B 2 118 ? 2.27400   14.25200 21.58700  1.000 36.30213  ? 118 PHE   L CA  1 
ATOM   2532 C  C   . PHE   B 2 118 ? 3.08100   15.45100 21.11500  1.000 37.54589  ? 118 PHE   L C   1 
ATOM   2533 O  O   . PHE   B 2 118 ? 2.69500   16.14200 20.16800  1.000 39.83240  ? 118 PHE   L O   1 
ATOM   2534 C  CB  . PHE   B 2 118 ? 2.72400   12.98800 20.83900  1.000 34.68316  ? 118 PHE   L CB  1 
ATOM   2535 C  CG  . PHE   B 2 118 ? 1.78400   11.82700 20.99200  1.000 39.01542  ? 118 PHE   L CG  1 
ATOM   2536 C  CD1 . PHE   B 2 118 ? 1.95500   10.91200 22.01700  1.000 40.68721  ? 118 PHE   L CD1 1 
ATOM   2537 C  CD2 . PHE   B 2 118 ? 0.73200   11.64900 20.10900  1.000 42.13610  ? 118 PHE   L CD2 1 
ATOM   2538 C  CE1 . PHE   B 2 118 ? 1.09100   9.84300  22.16200  1.000 37.68535  ? 118 PHE   L CE1 1 
ATOM   2539 C  CE2 . PHE   B 2 118 ? -0.13600  10.58300 20.24900  1.000 40.73090  ? 118 PHE   L CE2 1 
ATOM   2540 C  CZ  . PHE   B 2 118 ? 0.04500   9.67900  21.27700  1.000 39.30984  ? 118 PHE   L CZ  1 
ATOM   2541 N  N   . ILE   B 2 119 ? 4.20000   15.70200 21.78800  1.000 36.69699  ? 119 ILE   L N   1 
ATOM   2542 C  CA  . ILE   B 2 119 ? 5.08000   16.81300 21.45100  1.000 37.37318  ? 119 ILE   L CA  1 
ATOM   2543 C  C   . ILE   B 2 119 ? 6.49400   16.27300 21.28400  1.000 36.74880  ? 119 ILE   L C   1 
ATOM   2544 O  O   . ILE   B 2 119 ? 6.94600   15.43800 22.07500  1.000 34.91582  ? 119 ILE   L O   1 
ATOM   2545 C  CB  . ILE   B 2 119 ? 5.01800   17.93600 22.51000  1.000 40.44321  ? 119 ILE   L CB  1 
ATOM   2546 C  CG1 . ILE   B 2 119 ? 5.69600   19.20800 21.99500  1.000 38.18885  ? 119 ILE   L CG1 1 
ATOM   2547 C  CG2 . ILE   B 2 119 ? 5.60900   17.48900 23.84500  1.000 31.25244  ? 119 ILE   L CG2 1 
ATOM   2548 C  CD1 . ILE   B 2 119 ? 5.60500   20.37300 22.95400  1.000 39.21079  ? 119 ILE   L CD1 1 
ATOM   2549 N  N   . PHE   B 2 120 ? 7.17700   16.72400 20.23500  1.000 37.96436  ? 120 PHE   L N   1 
ATOM   2550 C  CA  . PHE   B 2 120 ? 8.51300   16.24300 19.90900  1.000 37.50409  ? 120 PHE   L CA  1 
ATOM   2551 C  C   . PHE   B 2 120 ? 9.50000   17.39800 19.97400  1.000 40.11238  ? 120 PHE   L C   1 
ATOM   2552 O  O   . PHE   B 2 120 ? 9.39100   18.34300 19.17300  1.000 36.94045  ? 120 PHE   L O   1 
ATOM   2553 C  CB  . PHE   B 2 120 ? 8.54400   15.60300 18.52000  1.000 32.07597  ? 120 PHE   L CB  1 
ATOM   2554 C  CG  . PHE   B 2 120 ? 7.66000   14.40000 18.38800  1.000 34.91892  ? 120 PHE   L CG  1 
ATOM   2555 C  CD1 . PHE   B 2 120 ? 8.13500   13.14000 18.70900  1.000 39.00494  ? 120 PHE   L CD1 1 
ATOM   2556 C  CD2 . PHE   B 2 120 ? 6.35700   14.52800 17.93900  1.000 33.41200  ? 120 PHE   L CD2 1 
ATOM   2557 C  CE1 . PHE   B 2 120 ? 7.32600   12.02900 18.58600  1.000 39.82068  ? 120 PHE   L CE1 1 
ATOM   2558 C  CE2 . PHE   B 2 120 ? 5.54200   13.42000 17.81500  1.000 37.66542  ? 120 PHE   L CE2 1 
ATOM   2559 C  CZ  . PHE   B 2 120 ? 6.02700   12.16900 18.13900  1.000 39.37525  ? 120 PHE   L CZ  1 
ATOM   2560 N  N   . PRO   B 2 121 ? 10.46400  17.37800 20.88800  1.000 43.21329  ? 121 PRO   L N   1 
ATOM   2561 C  CA  . PRO   B 2 121 ? 11.51800  18.38900 20.87200  1.000 43.10204  ? 121 PRO   L CA  1 
ATOM   2562 C  C   . PRO   B 2 121 ? 12.35900  18.24600 19.61900  1.000 47.10347  ? 121 PRO   L C   1 
ATOM   2563 O  O   . PRO   B 2 121 ? 12.36700  17.17700 18.98900  1.000 47.32703  ? 121 PRO   L O   1 
ATOM   2564 C  CB  . PRO   B 2 121 ? 12.33700  18.07000 22.13100  1.000 42.71376  ? 121 PRO   L CB  1 
ATOM   2565 C  CG  . PRO   B 2 121 ? 12.07500  16.63200 22.39600  1.000 36.73086  ? 121 PRO   L CG  1 
ATOM   2566 C  CD  . PRO   B 2 121 ? 10.66600  16.37800 21.95100  1.000 32.85496  ? 121 PRO   L CD  1 
ATOM   2567 N  N   . PRO   B 2 122 ? 13.06600  19.29600 19.21300  1.000 50.33786  ? 122 PRO   L N   1 
ATOM   2568 C  CA  . PRO   B 2 122 ? 13.97000  19.15800 18.06800  1.000 50.94843  ? 122 PRO   L CA  1 
ATOM   2569 C  C   . PRO   B 2 122 ? 15.01900  18.09100 18.34500  1.000 44.46546  ? 122 PRO   L C   1 
ATOM   2570 O  O   . PRO   B 2 122 ? 15.43400  17.88000 19.48600  1.000 45.84473  ? 122 PRO   L O   1 
ATOM   2571 C  CB  . PRO   B 2 122 ? 14.60000  20.55000 17.93500  1.000 45.24834  ? 122 PRO   L CB  1 
ATOM   2572 C  CG  . PRO   B 2 122 ? 14.33600  21.23000 19.24300  1.000 43.47312  ? 122 PRO   L CG  1 
ATOM   2573 C  CD  . PRO   B 2 122 ? 13.04800  20.66900 19.74300  1.000 41.97770  ? 122 PRO   L CD  1 
ATOM   2574 N  N   . SER   B 2 123 ? 15.43100  17.40200 17.28500  1.000 45.94133  ? 123 SER   L N   1 
ATOM   2575 C  CA  . SER   B 2 123 ? 16.56800  16.49800 17.37200  1.000 50.67059  ? 123 SER   L CA  1 
ATOM   2576 C  C   . SER   B 2 123 ? 17.82700  17.31200 17.63700  1.000 54.23026  ? 123 SER   L C   1 
ATOM   2577 O  O   . SER   B 2 123 ? 17.77500  18.54600 17.65700  1.000 56.26261  ? 123 SER   L O   1 
ATOM   2578 C  CB  . SER   B 2 123 ? 16.70600  15.69400 16.08300  1.000 48.28886  ? 123 SER   L CB  1 
ATOM   2579 O  OG  . SER   B 2 123 ? 16.40500  16.50400 14.95700  1.000 53.51391  ? 123 SER   L OG  1 
ATOM   2580 N  N   . ASP   B 2 124 ? 18.96100  16.65000 17.85600  1.000 57.66060  ? 124 ASP   L N   1 
ATOM   2581 C  CA  . ASP   B 2 124 ? 20.21400  17.37900 17.97300  1.000 56.48020  ? 124 ASP   L CA  1 
ATOM   2582 C  C   . ASP   B 2 124 ? 21.04500  17.32500 16.70500  1.000 60.67713  ? 124 ASP   L C   1 
ATOM   2583 O  O   . ASP   B 2 124 ? 21.94400  18.15500 16.53900  1.000 63.53200  ? 124 ASP   L O   1 
ATOM   2584 C  CB  . ASP   B 2 124 ? 21.03300  16.86200 19.15900  1.000 59.54877  ? 124 ASP   L CB  1 
ATOM   2585 C  CG  . ASP   B 2 124 ? 20.31300  17.05400 20.47900  1.000 62.82891  ? 124 ASP   L CG  1 
ATOM   2586 O  OD1 . ASP   B 2 124 ? 19.44300  17.95200 20.56900  1.000 64.99047  ? 124 ASP   L OD1 1 
ATOM   2587 O  OD2 . ASP   B 2 124 ? 20.60100  16.29100 21.42100  1.000 57.69892  ? 124 ASP   L OD2 1 
ATOM   2588 N  N   . GLU   B 2 125 ? 20.75300  16.39300 15.80000  1.000 63.36947  ? 125 GLU   L N   1 
ATOM   2589 C  CA  . GLU   B 2 125 ? 21.19200  16.56800 14.42400  1.000 63.65208  ? 125 GLU   L CA  1 
ATOM   2590 C  C   . GLU   B 2 125 ? 20.68300  17.89700 13.87100  1.000 58.35241  ? 125 GLU   L C   1 
ATOM   2591 O  O   . GLU   B 2 125 ? 21.41500  18.61500 13.18100  1.000 62.55114  ? 125 GLU   L O   1 
ATOM   2592 C  CB  . GLU   B 2 125 ? 20.70600  15.40300 13.55900  1.000 60.39210  ? 125 GLU   L CB  1 
ATOM   2593 C  CG  . GLU   B 2 125 ? 21.22300  14.03100 13.97500  1.000 66.09974  ? 125 GLU   L CG  1 
ATOM   2594 C  CD  . GLU   B 2 125 ? 20.22200  13.27200 14.82500  1.000 67.08726  ? 125 GLU   L CD  1 
ATOM   2595 O  OE1 . GLU   B 2 125 ? 19.75500  13.83400 15.83700  1.000 63.56151  ? 125 GLU   L OE1 1 
ATOM   2596 O  OE2 . GLU   B 2 125 ? 19.88500  12.12200 14.47100  1.000 67.17588  ? 125 GLU   L OE2 1 
ATOM   2597 N  N   . GLN   B 2 126 ? 19.43200  18.25700 14.19400  1.000 55.97896  ? 126 GLN   L N   1 
ATOM   2598 C  CA  . GLN   B 2 126 ? 18.81300  19.43200 13.58200  1.000 56.52496  ? 126 GLN   L CA  1 
ATOM   2599 C  C   . GLN   B 2 126 ? 19.27200  20.73700 14.22400  1.000 56.22475  ? 126 GLN   L C   1 
ATOM   2600 O  O   . GLN   B 2 126 ? 19.18700  21.79400 13.59300  1.000 59.83733  ? 126 GLN   L O   1 
ATOM   2601 C  CB  . GLN   B 2 126 ? 17.28900  19.35000 13.65900  1.000 49.45666  ? 126 GLN   L CB  1 
ATOM   2602 C  CG  . GLN   B 2 126 ? 16.61900  20.36500 12.75600  1.000 48.32332  ? 126 GLN   L CG  1 
ATOM   2603 C  CD  . GLN   B 2 126 ? 15.17000  20.60500 13.08300  1.000 45.21857  ? 126 GLN   L CD  1 
ATOM   2604 O  OE1 . GLN   B 2 126 ? 14.64800  20.13500 14.09700  1.000 45.08352  ? 126 GLN   L OE1 1 
ATOM   2605 N  NE2 . GLN   B 2 126 ? 14.50600  21.35900 12.22200  1.000 42.59156  ? 126 GLN   L NE2 1 
ATOM   2606 N  N   . LEU   B 2 127 ? 19.73600  20.70000 15.47600  1.000 60.22331  ? 127 LEU   L N   1 
ATOM   2607 C  CA  . LEU   B 2 127 ? 20.24800  21.91600 16.10700  1.000 59.81815  ? 127 LEU   L CA  1 
ATOM   2608 C  C   . LEU   B 2 127 ? 21.67300  22.22000 15.65200  1.000 64.03130  ? 127 LEU   L C   1 
ATOM   2609 O  O   . LEU   B 2 127 ? 22.08300  23.38800 15.59000  1.000 64.83192  ? 127 LEU   L O   1 
ATOM   2610 C  CB  . LEU   B 2 127 ? 20.17800  21.78800 17.62900  1.000 67.63057  ? 127 LEU   L CB  1 
ATOM   2611 C  CG  . LEU   B 2 127 ? 18.70200  21.78500 18.04100  1.000 62.01596  ? 127 LEU   L CG  1 
ATOM   2612 C  CD1 . LEU   B 2 127 ? 18.45700  21.10000 19.40300  1.000 58.02300  ? 127 LEU   L CD1 1 
ATOM   2613 C  CD2 . LEU   B 2 127 ? 18.16000  23.21600 17.97400  1.000 60.27300  ? 127 LEU   L CD2 1 
ATOM   2614 N  N   . LYS   B 2 128 ? 22.44900  21.17800 15.34000  1.000 63.88380  ? 128 LYS   L N   1 
ATOM   2615 C  CA  . LYS   B 2 128 ? 23.63700  21.38600 14.52500  1.000 67.91990  ? 128 LYS   L CA  1 
ATOM   2616 C  C   . LYS   B 2 128 ? 23.30000  22.12700 13.23700  1.000 72.50273  ? 128 LYS   L C   1 
ATOM   2617 O  O   . LYS   B 2 128 ? 24.08000  22.97600 12.79200  1.000 66.37540  ? 128 LYS   L O   1 
ATOM   2618 C  CB  . LYS   B 2 128 ? 24.28500  20.05300 14.19200  1.000 66.34109  ? 128 LYS   L CB  1 
ATOM   2619 C  CG  . LYS   B 2 128 ? 24.83400  19.27000 15.37900  1.000 70.35689  ? 128 LYS   L CG  1 
ATOM   2620 C  CD  . LYS   B 2 128 ? 25.15200  17.82700 14.97800  1.000 74.41984  ? 128 LYS   L CD  1 
ATOM   2621 C  CE  . LYS   B 2 128 ? 25.21200  16.85600 16.15900  1.000 77.22864  ? 128 LYS   L CE  1 
ATOM   2622 N  NZ  . LYS   B 2 128 ? 24.65600  15.51500 15.79400  1.000 66.26966  ? 128 LYS   L NZ  1 
ATOM   2623 N  N   . SER   B 2 129 ? 22.16500  21.78900 12.59600  1.000 69.50584  ? 129 SER   L N   1 
ATOM   2624 C  CA  . SER   B 2 129 ? 21.82900  22.43600 11.32700  1.000 66.50386  ? 129 SER   L CA  1 
ATOM   2625 C  C   . SER   B 2 129 ? 21.69700  23.94200 11.50000  1.000 64.90875  ? 129 SER   L C   1 
ATOM   2626 O  O   . SER   B 2 129 ? 21.98600  24.70300 10.57100  1.000 57.62604  ? 129 SER   L O   1 
ATOM   2627 C  CB  . SER   B 2 129 ? 20.55000  21.84400 10.72800  1.000 69.25251  ? 129 SER   L CB  1 
ATOM   2628 O  OG  . SER   B 2 129 ? 19.39300  22.37600 11.32500  1.000 66.59520  ? 129 SER   L OG  1 
ATOM   2629 N  N   . GLY   B 2 130 ? 21.29500  24.38800 12.68600  1.000 57.50078  ? 130 GLY   L N   1 
ATOM   2630 C  CA  . GLY   B 2 130 ? 21.04400  25.78500 12.96500  1.000 48.50711  ? 130 GLY   L CA  1 
ATOM   2631 C  C   . GLY   B 2 130 ? 19.58100  26.13700 13.08600  1.000 49.67784  ? 130 GLY   L C   1 
ATOM   2632 O  O   . GLY   B 2 130 ? 19.27100  27.30500 13.33300  1.000 49.86587  ? 130 GLY   L O   1 
ATOM   2633 N  N   . THR   B 2 131 ? 18.67100  25.17300 12.91800  1.000 51.78681  ? 131 THR   L N   1 
ATOM   2634 C  CA  . THR   B 2 131 ? 17.23600  25.41100 13.00300  1.000 50.30129  ? 131 THR   L CA  1 
ATOM   2635 C  C   . THR   B 2 131 ? 16.61200  24.42400 13.98100  1.000 43.90227  ? 131 THR   L C   1 
ATOM   2636 O  O   . THR   B 2 131 ? 17.05200  23.27900 14.09300  1.000 51.79080  ? 131 THR   L O   1 
ATOM   2637 C  CB  . THR   B 2 131 ? 16.57700  25.28900 11.61600  1.000 54.59525  ? 131 THR   L CB  1 
ATOM   2638 O  OG1 . THR   B 2 131 ? 17.01400  26.37400 10.79100  1.000 53.38959  ? 131 THR   L OG1 1 
ATOM   2639 C  CG2 . THR   B 2 131 ? 15.06100  25.32000 11.70800  1.000 49.41596  ? 131 THR   L CG2 1 
ATOM   2640 N  N   . ALA   B 2 132 ? 15.59400  24.88600 14.70700  1.000 44.58614  ? 132 ALA   L N   1 
ATOM   2641 C  CA  . ALA   B 2 132 ? 14.87000  24.07700 15.68000  1.000 43.88103  ? 132 ALA   L CA  1 
ATOM   2642 C  C   . ALA   B 2 132 ? 13.43400  23.89500 15.20800  1.000 40.51329  ? 132 ALA   L C   1 
ATOM   2643 O  O   . ALA   B 2 132 ? 12.72100  24.88000 14.98900  1.000 44.72165  ? 132 ALA   L O   1 
ATOM   2644 C  CB  . ALA   B 2 132 ? 14.90000  24.73300 17.06200  1.000 44.06792  ? 132 ALA   L CB  1 
ATOM   2645 N  N   . SER   B 2 133 ? 13.01000  22.64300 15.05600  1.000 42.47115  ? 133 SER   L N   1 
ATOM   2646 C  CA  . SER   B 2 133 ? 11.63200  22.31200 14.71200  1.000 40.34737  ? 133 SER   L CA  1 
ATOM   2647 C  C   . SER   B 2 133 ? 10.98900  21.58600 15.88500  1.000 36.31304  ? 133 SER   L C   1 
ATOM   2648 O  O   . SER   B 2 133 ? 11.47200  20.52900 16.30400  1.000 40.84550  ? 133 SER   L O   1 
ATOM   2649 C  CB  . SER   B 2 133 ? 11.56500  21.44600 13.45400  1.000 34.75350  ? 133 SER   L CB  1 
ATOM   2650 O  OG  . SER   B 2 133 ? 12.17900  22.09000 12.35300  1.000 32.75712  ? 133 SER   L OG  1 
ATOM   2651 N  N   . VAL   B 2 134 ? 9.90300   22.15100 16.40500  1.000 32.98356  ? 134 VAL   L N   1 
ATOM   2652 C  CA  . VAL   B 2 134 ? 9.10700   21.52900 17.45500  1.000 32.77099  ? 134 VAL   L CA  1 
ATOM   2653 C  C   . VAL   B 2 134 ? 7.80100   21.06000 16.83100  1.000 34.22038  ? 134 VAL   L C   1 
ATOM   2654 O  O   . VAL   B 2 134 ? 7.08100   21.85100 16.20900  1.000 33.71697  ? 134 VAL   L O   1 
ATOM   2655 C  CB  . VAL   B 2 134 ? 8.85300   22.49700 18.62300  1.000 34.68303  ? 134 VAL   L CB  1 
ATOM   2656 C  CG1 . VAL   B 2 134 ? 8.34100   21.73700 19.83800  1.000 31.33541  ? 134 VAL   L CG1 1 
ATOM   2657 C  CG2 . VAL   B 2 134 ? 10.12400  23.27200 18.96000  1.000 38.32397  ? 134 VAL   L CG2 1 
ATOM   2658 N  N   . VAL   B 2 135 ? 7.49600   19.77700 16.99900  1.000 33.90431  ? 135 VAL   L N   1 
ATOM   2659 C  CA  . VAL   B 2 135 ? 6.35700   19.13900 16.35200  1.000 33.46535  ? 135 VAL   L CA  1 
ATOM   2660 C  C   . VAL   B 2 135 ? 5.33300   18.76400 17.41000  1.000 34.49850  ? 135 VAL   L C   1 
ATOM   2661 O  O   . VAL   B 2 135 ? 5.69000   18.31100 18.50300  1.000 35.18735  ? 135 VAL   L O   1 
ATOM   2662 C  CB  . VAL   B 2 135 ? 6.80100   17.90000 15.54800  1.000 31.57335  ? 135 VAL   L CB  1 
ATOM   2663 C  CG1 . VAL   B 2 135 ? 5.60700   17.24400 14.86500  1.000 26.36173  ? 135 VAL   L CG1 1 
ATOM   2664 C  CG2 . VAL   B 2 135 ? 7.85900   18.28400 14.52700  1.000 33.12827  ? 135 VAL   L CG2 1 
ATOM   2665 N  N   . CYS   B 2 136 ? 4.05700   18.96500 17.08800  1.000 39.74564  ? 136 CYS   L N   1 
ATOM   2666 C  CA  . CYS   B 2 136 ? 2.95300   18.57300 17.95400  1.000 37.39993  ? 136 CYS   L CA  1 
ATOM   2667 C  C   . CYS   B 2 136 ? 1.99800   17.70900 17.15000  1.000 37.23495  ? 136 CYS   L C   1 
ATOM   2668 O  O   . CYS   B 2 136 ? 1.50400   18.13700 16.10100  1.000 36.32446  ? 136 CYS   L O   1 
ATOM   2669 C  CB  . CYS   B 2 136 ? 2.22400   19.79300 18.51700  1.000 35.54729  ? 136 CYS   L CB  1 
ATOM   2670 S  SG  . CYS   B 2 136 ? 1.11500   19.47200 19.90700  1.000 53.17211  ? 136 CYS   L SG  1 
ATOM   2671 N  N   . LEU   B 2 137 ? 1.73300   16.50400 17.64600  1.000 40.80201  ? 137 LEU   L N   1 
ATOM   2672 C  CA  . LEU   B 2 137 ? 0.89000   15.53400 16.96600  1.000 35.00078  ? 137 LEU   L CA  1 
ATOM   2673 C  C   . LEU   B 2 137 ? -0.45900  15.42200 17.66300  1.000 31.53723  ? 137 LEU   L C   1 
ATOM   2674 O  O   . LEU   B 2 137 ? -0.53400  15.39000 18.89500  1.000 37.34027  ? 137 LEU   L O   1 
ATOM   2675 C  CB  . LEU   B 2 137 ? 1.56600   14.16200 16.91900  1.000 29.59118  ? 137 LEU   L CB  1 
ATOM   2676 C  CG  . LEU   B 2 137 ? 0.71000   13.02400 16.36300  1.000 37.22812  ? 137 LEU   L CG  1 
ATOM   2677 C  CD1 . LEU   B 2 137 ? 0.37700   13.27100 14.89800  1.000 32.62354  ? 137 LEU   L CD1 1 
ATOM   2678 C  CD2 . LEU   B 2 137 ? 1.39700   11.67900 16.54800  1.000 34.38868  ? 137 LEU   L CD2 1 
ATOM   2679 N  N   . LEU   B 2 138 ? -1.52000  15.36800 16.86300  1.000 34.23714  ? 138 LEU   L N   1 
ATOM   2680 C  CA  . LEU   B 2 138 ? -2.88700  15.15100 17.33300  1.000 38.01359  ? 138 LEU   L CA  1 
ATOM   2681 C  C   . LEU   B 2 138 ? -3.40600  13.93200 16.58200  1.000 40.92377  ? 138 LEU   L C   1 
ATOM   2682 O  O   . LEU   B 2 138 ? -3.75700  14.03300 15.40300  1.000 37.63638  ? 138 LEU   L O   1 
ATOM   2683 C  CB  . LEU   B 2 138 ? -3.76400  16.37300 17.07700  1.000 36.13940  ? 138 LEU   L CB  1 
ATOM   2684 C  CG  . LEU   B 2 138 ? -3.66800  17.60400 17.97800  1.000 37.83343  ? 138 LEU   L CG  1 
ATOM   2685 C  CD1 . LEU   B 2 138 ? -2.32200  18.30900 17.85000  1.000 38.56397  ? 138 LEU   L CD1 1 
ATOM   2686 C  CD2 . LEU   B 2 138 ? -4.80300  18.54800 17.62800  1.000 39.09952  ? 138 LEU   L CD2 1 
ATOM   2687 N  N   . ASN   B 2 139 ? -3.45800  12.78400 17.25000  1.000 35.74887  ? 139 ASN   L N   1 
ATOM   2688 C  CA  . ASN   B 2 139 ? -3.70300  11.51100 16.58400  1.000 38.24660  ? 139 ASN   L CA  1 
ATOM   2689 C  C   . ASN   B 2 139 ? -5.18200  11.15000 16.65000  1.000 40.65365  ? 139 ASN   L C   1 
ATOM   2690 O  O   . ASN   B 2 139 ? -5.75900  11.07100 17.73900  1.000 37.48367  ? 139 ASN   L O   1 
ATOM   2691 C  CB  . ASN   B 2 139 ? -2.85900  10.40000 17.20600  1.000 44.37683  ? 139 ASN   L CB  1 
ATOM   2692 C  CG  . ASN   B 2 139 ? -3.36600  9.01500  16.84500  1.000 49.43994  ? 139 ASN   L CG  1 
ATOM   2693 O  OD1 . ASN   B 2 139 ? -3.15400  8.53400  15.72900  1.000 47.41899  ? 139 ASN   L OD1 1 
ATOM   2694 N  ND2 . ASN   B 2 139 ? -4.03900  8.36500  17.79000  1.000 45.18582  ? 139 ASN   L ND2 1 
ATOM   2695 N  N   . ASN   B 2 140 ? -5.77900  10.92900 15.47700  1.000 43.22573  ? 140 ASN   L N   1 
ATOM   2696 C  CA  . ASN   B 2 140 ? -7.10900  10.34900 15.30900  1.000 43.87726  ? 140 ASN   L CA  1 
ATOM   2697 C  C   . ASN   B 2 140 ? -8.17200  10.97500 16.20000  1.000 37.47609  ? 140 ASN   L C   1 
ATOM   2698 O  O   . ASN   B 2 140 ? -8.46100  10.47900 17.29300  1.000 38.39256  ? 140 ASN   L O   1 
ATOM   2699 C  CB  . ASN   B 2 140 ? -7.04200  8.83800  15.51300  1.000 45.39089  ? 140 ASN   L CB  1 
ATOM   2700 C  CG  . ASN   B 2 140 ? -6.12300  8.17300  14.51000  1.000 53.01881  ? 140 ASN   L CG  1 
ATOM   2701 O  OD1 . ASN   B 2 140 ? -6.14700  8.48900  13.31900  1.000 57.40402  ? 140 ASN   L OD1 1 
ATOM   2702 N  ND2 . ASN   B 2 140 ? -5.29000  7.27400  14.98700  1.000 41.05036  ? 140 ASN   L ND2 1 
ATOM   2703 N  N   . PHE   B 2 141 ? -8.76700  12.05800 15.71200  1.000 41.34821  ? 141 PHE   L N   1 
ATOM   2704 C  CA  . PHE   B 2 141 ? -9.83700  12.77400 16.38400  1.000 40.25025  ? 141 PHE   L CA  1 
ATOM   2705 C  C   . PHE   B 2 141 ? -10.92700 13.08900 15.36900  1.000 40.00124  ? 141 PHE   L C   1 
ATOM   2706 O  O   . PHE   B 2 141 ? -10.76800 12.87100 14.16400  1.000 36.63905  ? 141 PHE   L O   1 
ATOM   2707 C  CB  . PHE   B 2 141 ? -9.31900  14.06800 17.02700  1.000 36.93979  ? 141 PHE   L CB  1 
ATOM   2708 C  CG  . PHE   B 2 141 ? -8.66700  15.00500 16.05000  1.000 35.00863  ? 141 PHE   L CG  1 
ATOM   2709 C  CD1 . PHE   B 2 141 ? -7.33000  14.86300 15.71600  1.000 33.74116  ? 141 PHE   L CD1 1 
ATOM   2710 C  CD2 . PHE   B 2 141 ? -9.39400  16.02400 15.45900  1.000 40.39594  ? 141 PHE   L CD2 1 
ATOM   2711 C  CE1 . PHE   B 2 141 ? -6.73000  15.72100 14.81100  1.000 37.79182  ? 141 PHE   L CE1 1 
ATOM   2712 C  CE2 . PHE   B 2 141 ? -8.80100  16.88600 14.55300  1.000 39.30559  ? 141 PHE   L CE2 1 
ATOM   2713 C  CZ  . PHE   B 2 141 ? -7.46700  16.73400 14.22900  1.000 38.18356  ? 141 PHE   L CZ  1 
ATOM   2714 N  N   . TYR   B 2 142 ? -12.04700 13.61400 15.87100  1.000 38.66279  ? 142 TYR   L N   1 
ATOM   2715 C  CA  . TYR   B 2 142 ? -13.12200 14.09800 15.01700  1.000 36.56263  ? 142 TYR   L CA  1 
ATOM   2716 C  C   . TYR   B 2 142 ? -13.98900 15.03000 15.84300  1.000 42.21415  ? 142 TYR   L C   1 
ATOM   2717 O  O   . TYR   B 2 142 ? -14.27600 14.71100 17.00500  1.000 43.17225  ? 142 TYR   L O   1 
ATOM   2718 C  CB  . TYR   B 2 142 ? -13.96400 12.95000 14.44800  1.000 38.21860  ? 142 TYR   L CB  1 
ATOM   2719 C  CG  . TYR   B 2 142 ? -14.98200 13.41700 13.43600  1.000 34.34300  ? 142 TYR   L CG  1 
ATOM   2720 C  CD1 . TYR   B 2 142 ? -14.62900 13.60900 12.10600  1.000 44.26301  ? 142 TYR   L CD1 1 
ATOM   2721 C  CD2 . TYR   B 2 142 ? -16.28900 13.69100 13.81300  1.000 38.53101  ? 142 TYR   L CD2 1 
ATOM   2722 C  CE1 . TYR   B 2 142 ? -15.55300 14.05100 11.17800  1.000 46.13862  ? 142 TYR   L CE1 1 
ATOM   2723 C  CE2 . TYR   B 2 142 ? -17.22000 14.13300 12.89200  1.000 42.13343  ? 142 TYR   L CE2 1 
ATOM   2724 C  CZ  . TYR   B 2 142 ? -16.84600 14.31000 11.57600  1.000 45.10109  ? 142 TYR   L CZ  1 
ATOM   2725 O  OH  . TYR   B 2 142 ? -17.77000 14.74900 10.65500  1.000 51.81260  ? 142 TYR   L OH  1 
ATOM   2726 N  N   . PRO   B 2 143 ? -14.43800 16.17200 15.29300  1.000 45.93414  ? 143 PRO   L N   1 
ATOM   2727 C  CA  . PRO   B 2 143 ? -14.28300 16.62900 13.90400  1.000 42.26018  ? 143 PRO   L CA  1 
ATOM   2728 C  C   . PRO   B 2 143 ? -12.90100 17.18600 13.58200  1.000 43.63945  ? 143 PRO   L C   1 
ATOM   2729 O  O   . PRO   B 2 143 ? -12.02300 17.19100 14.44200  1.000 45.39814  ? 143 PRO   L O   1 
ATOM   2730 C  CB  . PRO   B 2 143 ? -15.34500 17.73400 13.77300  1.000 38.27115  ? 143 PRO   L CB  1 
ATOM   2731 C  CG  . PRO   B 2 143 ? -16.06500 17.79400 15.10400  1.000 39.35533  ? 143 PRO   L CG  1 
ATOM   2732 C  CD  . PRO   B 2 143 ? -15.17200 17.15400 16.10400  1.000 40.24998  ? 143 PRO   L CD  1 
ATOM   2733 N  N   . ARG   B 2 144 ? -12.71800 17.64900 12.34200  1.000 44.60572  ? 144 ARG   L N   1 
ATOM   2734 C  CA  . ARG   B 2 144 ? -11.43100 18.21300 11.95000  1.000 49.59262  ? 144 ARG   L CA  1 
ATOM   2735 C  C   . ARG   B 2 144 ? -11.12600 19.50200 12.70400  1.000 46.18899  ? 144 ARG   L C   1 
ATOM   2736 O  O   . ARG   B 2 144 ? -9.95300  19.83500 12.91000  1.000 44.68559  ? 144 ARG   L O   1 
ATOM   2737 C  CB  . ARG   B 2 144 ? -11.40100 18.45700 10.44100  1.000 42.97032  ? 144 ARG   L CB  1 
ATOM   2738 C  CG  . ARG   B 2 144 ? -10.01800 18.76800 9.88500   1.000 44.98190  ? 144 ARG   L CG  1 
ATOM   2739 C  CD  . ARG   B 2 144 ? -9.98500  20.15500 9.26600   1.000 57.80515  ? 144 ARG   L CD  1 
ATOM   2740 N  NE  . ARG   B 2 144 ? -8.63300  20.69900 9.16600   1.000 63.44417  ? 144 ARG   L NE  1 
ATOM   2741 C  CZ  . ARG   B 2 144 ? -7.95500  21.21700 10.18600  1.000 65.60698  ? 144 ARG   L CZ  1 
ATOM   2742 N  NH1 . ARG   B 2 144 ? -8.49400  21.25600 11.39700  1.000 55.78690  ? 144 ARG   L NH1 1 
ATOM   2743 N  NH2 . ARG   B 2 144 ? -6.73400  21.69900 9.99700   1.000 69.20431  ? 144 ARG   L NH2 1 
ATOM   2744 N  N   . GLU   B 2 145 ? -12.15900 20.22600 13.13500  1.000 42.02822  ? 145 GLU   L N   1 
ATOM   2745 C  CA  . GLU   B 2 145 ? -11.96200 21.49900 13.81900  1.000 47.55221  ? 145 GLU   L CA  1 
ATOM   2746 C  C   . GLU   B 2 145 ? -11.21800 21.29600 15.13300  1.000 45.48680  ? 145 GLU   L C   1 
ATOM   2747 O  O   . GLU   B 2 145 ? -11.69900 20.59200 16.02600  1.000 46.06732  ? 145 GLU   L O   1 
ATOM   2748 C  CB  . GLU   B 2 145 ? -13.31000 22.17400 14.07100  1.000 53.19410  ? 145 GLU   L CB  1 
ATOM   2749 C  CG  . GLU   B 2 145 ? -13.77600 23.08800 12.94200  1.000 67.01052  ? 145 GLU   L CG  1 
ATOM   2750 C  CD  . GLU   B 2 145 ? -13.86000 22.37400 11.60800  1.000 67.01134  ? 145 GLU   L CD  1 
ATOM   2751 O  OE1 . GLU   B 2 145 ? -12.93600 22.53700 10.78300  1.000 66.07234  ? 145 GLU   L OE1 1 
ATOM   2752 O  OE2 . GLU   B 2 145 ? -14.84800 21.64300 11.39000  1.000 59.51445  ? 145 GLU   L OE2 1 
ATOM   2753 N  N   . ALA   B 2 146 ? -10.04100 21.91000 15.24300  1.000 45.19262  ? 146 ALA   L N   1 
ATOM   2754 C  CA  . ALA   B 2 146 ? -9.23100  21.83500 16.45100  1.000 44.01625  ? 146 ALA   L CA  1 
ATOM   2755 C  C   . ALA   B 2 146 ? -8.33000  23.05800 16.50500  1.000 43.63856  ? 146 ALA   L C   1 
ATOM   2756 O  O   . ALA   B 2 146 ? -7.98500  23.63400 15.47000  1.000 52.25490  ? 146 ALA   L O   1 
ATOM   2757 C  CB  . ALA   B 2 146 ? -8.39700  20.54900 16.49800  1.000 46.32163  ? 146 ALA   L CB  1 
ATOM   2758 N  N   . LYS   B 2 147 ? -7.95200  23.44300 17.72200  1.000 48.16591  ? 147 LYS   L N   1 
ATOM   2759 C  CA  . LYS   B 2 147 ? -7.15900  24.64500 17.96400  1.000 44.66293  ? 147 LYS   L CA  1 
ATOM   2760 C  C   . LYS   B 2 147 ? -5.85100  24.24700 18.63600  1.000 43.74875  ? 147 LYS   L C   1 
ATOM   2761 O  O   . LYS   B 2 147 ? -5.85400  23.76300 19.77400  1.000 49.25533  ? 147 LYS   L O   1 
ATOM   2762 C  CB  . LYS   B 2 147 ? -7.93400  25.64500 18.82200  1.000 50.02283  ? 147 LYS   L CB  1 
ATOM   2763 C  CG  . LYS   B 2 147 ? -7.35800  27.05100 18.83000  1.000 50.71101  ? 147 LYS   L CG  1 
ATOM   2764 C  CD  . LYS   B 2 147 ? -7.40700  27.65200 20.22600  1.000 56.78434  ? 147 LYS   L CD  1 
ATOM   2765 C  CE  . LYS   B 2 147 ? -8.08600  29.01300 20.22000  1.000 64.82838  ? 147 LYS   L CE  1 
ATOM   2766 N  NZ  . LYS   B 2 147 ? -7.40500  29.97600 19.31000  1.000 66.29320  ? 147 LYS   L NZ  1 
ATOM   2767 N  N   . VAL   B 2 148 ? -4.73900  24.45600 17.93600  1.000 44.12141  ? 148 VAL   L N   1 
ATOM   2768 C  CA  . VAL   B 2 148 ? -3.40300  24.15300 18.43600  1.000 45.45101  ? 148 VAL   L CA  1 
ATOM   2769 C  C   . VAL   B 2 148 ? -2.64100  25.46200 18.58500  1.000 49.08890  ? 148 VAL   L C   1 
ATOM   2770 O  O   . VAL   B 2 148 ? -2.64100  26.29500 17.67100  1.000 46.97609  ? 148 VAL   L O   1 
ATOM   2771 C  CB  . VAL   B 2 148 ? -2.65900  23.18400 17.50100  1.000 41.39578  ? 148 VAL   L CB  1 
ATOM   2772 C  CG1 . VAL   B 2 148 ? -1.24200  22.94400 17.99400  1.000 47.76206  ? 148 VAL   L CG1 1 
ATOM   2773 C  CG2 . VAL   B 2 148 ? -3.42000  21.87500 17.39000  1.000 41.83485  ? 148 VAL   L CG2 1 
ATOM   2774 N  N   . GLN   B 2 149 ? -1.99500  25.64400 19.73500  1.000 51.58166  ? 149 GLN   L N   1 
ATOM   2775 C  CA  . GLN   B 2 149 ? -1.27700  26.87400 20.03000  1.000 45.15871  ? 149 GLN   L CA  1 
ATOM   2776 C  C   . GLN   B 2 149 ? 0.04100   26.55400 20.71500  1.000 46.37174  ? 149 GLN   L C   1 
ATOM   2777 O  O   . GLN   B 2 149 ? 0.11000   25.66600 21.56900  1.000 49.77031  ? 149 GLN   L O   1 
ATOM   2778 C  CB  . GLN   B 2 149 ? -2.10800  27.80600 20.91700  1.000 52.01142  ? 149 GLN   L CB  1 
ATOM   2779 C  CG  . GLN   B 2 149 ? -3.16100  28.59300 20.16400  1.000 51.61784  ? 149 GLN   L CG  1 
ATOM   2780 C  CD  . GLN   B 2 149 ? -3.96700  29.49300 21.07400  1.000 52.37366  ? 149 GLN   L CD  1 
ATOM   2781 O  OE1 . GLN   B 2 149 ? -4.18600  29.17600 22.24300  1.000 59.41808  ? 149 GLN   L OE1 1 
ATOM   2782 N  NE2 . GLN   B 2 149 ? -4.41300  30.62600 20.54400  1.000 43.82293  ? 149 GLN   L NE2 1 
ATOM   2783 N  N   . TRP   B 2 150 ? 1.08100   27.29100 20.34000  1.000 46.62526  ? 150 TRP   L N   1 
ATOM   2784 C  CA  . TRP   B 2 150 ? 2.40300   27.14200 20.92400  1.000 40.48662  ? 150 TRP   L CA  1 
ATOM   2785 C  C   . TRP   B 2 150 ? 2.64500   28.22300 21.96700  1.000 39.82885  ? 150 TRP   L C   1 
ATOM   2786 O  O   . TRP   B 2 150 ? 2.29700   29.39000 21.76300  1.000 36.61176  ? 150 TRP   L O   1 
ATOM   2787 C  CB  . TRP   B 2 150 ? 3.48400   27.21100 19.84700  1.000 37.94553  ? 150 TRP   L CB  1 
ATOM   2788 C  CG  . TRP   B 2 150 ? 3.47100   26.03100 18.94000  1.000 35.74300  ? 150 TRP   L CG  1 
ATOM   2789 C  CD1 . TRP   B 2 150 ? 2.92300   25.95800 17.69500  1.000 35.55369  ? 150 TRP   L CD1 1 
ATOM   2790 C  CD2 . TRP   B 2 150 ? 4.01700   24.73800 19.21700  1.000 42.27328  ? 150 TRP   L CD2 1 
ATOM   2791 N  NE1 . TRP   B 2 150 ? 3.10300   24.69900 17.17300  1.000 38.13870  ? 150 TRP   L NE1 1 
ATOM   2792 C  CE2 . TRP   B 2 150 ? 3.77100   23.93100 18.08900  1.000 41.02316  ? 150 TRP   L CE2 1 
ATOM   2793 C  CE3 . TRP   B 2 150 ? 4.69300   24.18600 20.30900  1.000 33.38877  ? 150 TRP   L CE3 1 
ATOM   2794 C  CZ2 . TRP   B 2 150 ? 4.18100   22.60200 18.02100  1.000 39.27803  ? 150 TRP   L CZ2 1 
ATOM   2795 C  CZ3 . TRP   B 2 150 ? 5.09400   22.86900 20.24200  1.000 34.37654  ? 150 TRP   L CZ3 1 
ATOM   2796 C  CH2 . TRP   B 2 150 ? 4.83900   22.09000 19.10600  1.000 42.03981  ? 150 TRP   L CH2 1 
ATOM   2797 N  N   . LYS   B 2 151 ? 3.24100   27.82500 23.08600  1.000 40.15462  ? 151 LYS   L N   1 
ATOM   2798 C  CA  . LYS   B 2 151 ? 3.63700   28.75000 24.13800  1.000 36.34016  ? 151 LYS   L CA  1 
ATOM   2799 C  C   . LYS   B 2 151 ? 5.08100   28.45600 24.50300  1.000 37.05057  ? 151 LYS   L C   1 
ATOM   2800 O  O   . LYS   B 2 151 ? 5.40800   27.32900 24.88900  1.000 47.21529  ? 151 LYS   L O   1 
ATOM   2801 C  CB  . LYS   B 2 151 ? 2.72700   28.62800 25.36300  1.000 36.36799  ? 151 LYS   L CB  1 
ATOM   2802 C  CG  . LYS   B 2 151 ? 1.31300   29.14200 25.13200  1.000 40.58473  ? 151 LYS   L CG  1 
ATOM   2803 C  CD  . LYS   B 2 151 ? 0.51100   29.18600 26.42200  1.000 45.29612  ? 151 LYS   L CD  1 
ATOM   2804 C  CE  . LYS   B 2 151 ? -0.81300  29.90500 26.21800  1.000 53.34122  ? 151 LYS   L CE  1 
ATOM   2805 N  NZ  . LYS   B 2 151 ? -1.55700  30.08600 27.49500  1.000 57.99564  ? 151 LYS   L NZ  1 
ATOM   2806 N  N   . VAL   B 2 152 ? 5.94200   29.45800 24.36700  1.000 34.41056  ? 152 VAL   L N   1 
ATOM   2807 C  CA  . VAL   B 2 152 ? 7.36200   29.32800 24.66100  1.000 39.37080  ? 152 VAL   L CA  1 
ATOM   2808 C  C   . VAL   B 2 152 ? 7.66600   30.19500 25.87400  1.000 49.70567  ? 152 VAL   L C   1 
ATOM   2809 O  O   . VAL   B 2 152 ? 7.49700   31.42000 25.82800  1.000 44.52163  ? 152 VAL   L O   1 
ATOM   2810 C  CB  . VAL   B 2 152 ? 8.22600   29.72400 23.45700  1.000 37.93570  ? 152 VAL   L CB  1 
ATOM   2811 C  CG1 . VAL   B 2 152 ? 9.67200   29.47300 23.76400  1.000 46.73927  ? 152 VAL   L CG1 1 
ATOM   2812 C  CG2 . VAL   B 2 152 ? 7.80400   28.93400 22.22900  1.000 41.55539  ? 152 VAL   L CG2 1 
ATOM   2813 N  N   . ASP   B 2 153 ? 8.12100   29.55700 26.95400  1.000 52.20044  ? 153 ASP   L N   1 
ATOM   2814 C  CA  . ASP   B 2 153 ? 8.20800   30.20000 28.26400  1.000 48.74783  ? 153 ASP   L CA  1 
ATOM   2815 C  C   . ASP   B 2 153 ? 6.89400   30.90400 28.59600  1.000 43.42584  ? 153 ASP   L C   1 
ATOM   2816 O  O   . ASP   B 2 153 ? 6.87000   32.03100 29.09500  1.000 43.71485  ? 153 ASP   L O   1 
ATOM   2817 C  CB  . ASP   B 2 153 ? 9.39600   31.16100 28.33900  1.000 45.82975  ? 153 ASP   L CB  1 
ATOM   2818 C  CG  . ASP   B 2 153 ? 10.73200  30.43500 28.38000  1.000 54.91141  ? 153 ASP   L CG  1 
ATOM   2819 O  OD1 . ASP   B 2 153 ? 10.75200  29.21100 28.12600  1.000 53.05025  ? 153 ASP   L OD1 1 
ATOM   2820 O  OD2 . ASP   B 2 153 ? 11.75900  31.08100 28.67200  1.000 60.94250  ? 153 ASP   L OD2 1 
ATOM   2821 N  N   . ASN   B 2 154 ? 5.78800   30.22200 28.28500  1.000 45.16112  ? 154 ASN   L N   1 
ATOM   2822 C  CA  . ASN   B 2 154 ? 4.42600   30.67700 28.57200  1.000 45.03122  ? 154 ASN   L CA  1 
ATOM   2823 C  C   . ASN   B 2 154 ? 4.07100   31.95600 27.81900  1.000 42.31133  ? 154 ASN   L C   1 
ATOM   2824 O  O   . ASN   B 2 154 ? 3.28200   32.77300 28.30100  1.000 49.24673  ? 154 ASN   L O   1 
ATOM   2825 C  CB  . ASN   B 2 154 ? 4.19600   30.86100 30.07500  1.000 54.53158  ? 154 ASN   L CB  1 
ATOM   2826 C  CG  . ASN   B 2 154 ? 2.73100   30.74400 30.45500  1.000 59.83927  ? 154 ASN   L CG  1 
ATOM   2827 O  OD1 . ASN   B 2 154 ? 1.99900   29.92700 29.89600  1.000 53.07350  ? 154 ASN   L OD1 1 
ATOM   2828 N  ND2 . ASN   B 2 154 ? 2.29600   31.56400 31.40500  1.000 63.63811  ? 154 ASN   L ND2 1 
ATOM   2829 N  N   . ALA   B 2 155 ? 4.63200   32.13900 26.62700  1.000 40.71032  ? 155 ALA   L N   1 
ATOM   2830 C  CA  . ALA   B 2 155 ? 4.28500   33.25600 25.75700  1.000 36.09236  ? 155 ALA   L CA  1 
ATOM   2831 C  C   . ALA   B 2 155 ? 3.69000   32.69900 24.47300  1.000 39.16160  ? 155 ALA   L C   1 
ATOM   2832 O  O   . ALA   B 2 155 ? 4.33800   31.90700 23.78000  1.000 41.67963  ? 155 ALA   L O   1 
ATOM   2833 C  CB  . ALA   B 2 155 ? 5.50500   34.12900 25.45900  1.000 31.97499  ? 155 ALA   L CB  1 
ATOM   2834 N  N   . LEU   B 2 156 ? 2.46400   33.10900 24.15600  1.000 38.39760  ? 156 LEU   L N   1 
ATOM   2835 C  CA  . LEU   B 2 156 ? 1.77400   32.56900 22.99100  1.000 36.14864  ? 156 LEU   L CA  1 
ATOM   2836 C  C   . LEU   B 2 156 ? 2.46900   33.00800 21.70800  1.000 37.19872  ? 156 LEU   L C   1 
ATOM   2837 O  O   . LEU   B 2 156 ? 2.75900   34.19300 21.51700  1.000 43.33405  ? 156 LEU   L O   1 
ATOM   2838 C  CB  . LEU   B 2 156 ? 0.31300   33.01300 22.98400  1.000 28.68831  ? 156 LEU   L CB  1 
ATOM   2839 C  CG  . LEU   B 2 156 ? -0.46900  32.64800 21.72300  1.000 38.49885  ? 156 LEU   L CG  1 
ATOM   2840 C  CD1 . LEU   B 2 156 ? -0.69100  31.14500 21.64600  1.000 44.67565  ? 156 LEU   L CD1 1 
ATOM   2841 C  CD2 . LEU   B 2 156 ? -1.79200  33.39300 21.67600  1.000 35.03673  ? 156 LEU   L CD2 1 
ATOM   2842 N  N   . GLN   B 2 157 ? 2.73000   32.04900 20.82600  1.000 38.87551  ? 157 GLN   L N   1 
ATOM   2843 C  CA  . GLN   B 2 157 ? 3.47400   32.30200 19.60400  1.000 36.72298  ? 157 GLN   L CA  1 
ATOM   2844 C  C   . GLN   B 2 157 ? 2.53700   32.66800 18.45900  1.000 38.46910  ? 157 GLN   L C   1 
ATOM   2845 O  O   . GLN   B 2 157 ? 1.34200   32.36000 18.47200  1.000 39.60274  ? 157 GLN   L O   1 
ATOM   2846 C  CB  . GLN   B 2 157 ? 4.31200   31.08300 19.22000  1.000 34.45014  ? 157 GLN   L CB  1 
ATOM   2847 C  CG  . GLN   B 2 157 ? 5.46800   30.81000 20.16100  1.000 37.42484  ? 157 GLN   L CG  1 
ATOM   2848 C  CD  . GLN   B 2 157 ? 6.27400   32.05400 20.47200  1.000 43.56327  ? 157 GLN   L CD  1 
ATOM   2849 O  OE1 . GLN   B 2 157 ? 7.00000   32.56900 19.62000  1.000 47.34423  ? 157 GLN   L OE1 1 
ATOM   2850 N  NE2 . GLN   B 2 157 ? 6.15000   32.54600 21.69800  1.000 39.74615  ? 157 GLN   L NE2 1 
ATOM   2851 N  N   . SER   B 2 158 ? 3.10500   33.32700 17.45300  1.000 39.17905  ? 158 SER   L N   1 
ATOM   2852 C  CA  . SER   B 2 158 ? 2.34200   33.78400 16.30300  1.000 37.24053  ? 158 SER   L CA  1 
ATOM   2853 C  C   . SER   B 2 158 ? 3.23100   33.77400 15.06900  1.000 33.26427  ? 158 SER   L C   1 
ATOM   2854 O  O   . SER   B 2 158 ? 4.38000   34.22200 15.11800  1.000 41.75868  ? 158 SER   L O   1 
ATOM   2855 C  CB  . SER   B 2 158 ? 1.77600   35.19000 16.53600  1.000 40.17542  ? 158 SER   L CB  1 
ATOM   2856 O  OG  . SER   B 2 158 ? 0.90300   35.56700 15.48600  1.000 41.32505  ? 158 SER   L OG  1 
ATOM   2857 N  N   . GLY   B 2 159 ? 2.69300   33.25100 13.96700  1.000 26.70479  ? 159 GLY   L N   1 
ATOM   2858 C  CA  . GLY   B 2 159 ? 3.35000   33.31400 12.68100  1.000 34.36024  ? 159 GLY   L CA  1 
ATOM   2859 C  C   . GLY   B 2 159 ? 4.41600   32.27000 12.42200  1.000 39.73262  ? 159 GLY   L C   1 
ATOM   2860 O  O   . GLY   B 2 159 ? 4.81900   32.09700 11.26600  1.000 36.01529  ? 159 GLY   L O   1 
ATOM   2861 N  N   . ASN   B 2 160 ? 4.89100   31.56400 13.44700  1.000 34.71575  ? 160 ASN   L N   1 
ATOM   2862 C  CA  . ASN   B 2 160 ? 5.97600   30.60400 13.28600  1.000 31.84114  ? 160 ASN   L CA  1 
ATOM   2863 C  C   . ASN   B 2 160 ? 5.49300   29.15800 13.39300  1.000 37.81047  ? 160 ASN   L C   1 
ATOM   2864 O  O   . ASN   B 2 160 ? 6.21700   28.29100 13.88900  1.000 37.25448  ? 160 ASN   L O   1 
ATOM   2865 C  CB  . ASN   B 2 160 ? 7.08400   30.87800 14.30200  1.000 36.97291  ? 160 ASN   L CB  1 
ATOM   2866 C  CG  . ASN   B 2 160 ? 6.54800   31.13000 15.70000  1.000 41.90657  ? 160 ASN   L CG  1 
ATOM   2867 O  OD1 . ASN   B 2 160 ? 5.33900   31.23500 15.90600  1.000 43.42078  ? 160 ASN   L OD1 1 
ATOM   2868 N  ND2 . ASN   B 2 160 ? 7.45000   31.22200 16.67200  1.000 36.96444  ? 160 ASN   L ND2 1 
ATOM   2869 N  N   . SER   B 2 161 ? 4.27800   28.88300 12.92200  1.000 36.86378  ? 161 SER   L N   1 
ATOM   2870 C  CA  . SER   B 2 161 ? 3.71300   27.54200 12.95100  1.000 31.63675  ? 161 SER   L CA  1 
ATOM   2871 C  C   . SER   B 2 161 ? 3.07000   27.22000 11.61000  1.000 38.32918  ? 161 SER   L C   1 
ATOM   2872 O  O   . SER   B 2 161 ? 2.59200   28.10900 10.90100  1.000 47.85899  ? 161 SER   L O   1 
ATOM   2873 C  CB  . SER   B 2 161 ? 2.67100   27.38700 14.06900  1.000 27.96096  ? 161 SER   L CB  1 
ATOM   2874 O  OG  . SER   B 2 161 ? 3.03600   28.13500 15.21400  1.000 41.53167  ? 161 SER   L OG  1 
ATOM   2875 N  N   . GLN   B 2 162 ? 3.06600   25.93200 11.27400  1.000 32.80074  ? 162 GLN   L N   1 
ATOM   2876 C  CA  . GLN   B 2 162 ? 2.42200   25.42900 10.06800  1.000 35.08880  ? 162 GLN   L CA  1 
ATOM   2877 C  C   . GLN   B 2 162 ? 1.75000   24.10800 10.40000  1.000 35.02532  ? 162 GLN   L C   1 
ATOM   2878 O  O   . GLN   B 2 162 ? 2.38900   23.21000 10.95400  1.000 40.81429  ? 162 GLN   L O   1 
ATOM   2879 C  CB  . GLN   B 2 162 ? 3.43000   25.23500 8.92900   1.000 39.29125  ? 162 GLN   L CB  1 
ATOM   2880 C  CG  . GLN   B 2 162 ? 3.69800   26.48300 8.10600   1.000 36.69679  ? 162 GLN   L CG  1 
ATOM   2881 C  CD  . GLN   B 2 162 ? 4.83000   26.29100 7.11500   1.000 41.18035  ? 162 GLN   L CD  1 
ATOM   2882 O  OE1 . GLN   B 2 162 ? 5.80400   25.59100 7.39300   1.000 41.15048  ? 162 GLN   L OE1 1 
ATOM   2883 N  NE2 . GLN   B 2 162 ? 4.70200   26.90700 5.94500   1.000 40.80947  ? 162 GLN   L NE2 1 
ATOM   2884 N  N   . GLU   B 2 163 ? 0.47100   23.99200 10.06500  1.000 32.79989  ? 163 GLU   L N   1 
ATOM   2885 C  CA  . GLU   B 2 163 ? -0.28400  22.77800 10.33100  1.000 33.12965  ? 163 GLU   L CA  1 
ATOM   2886 C  C   . GLU   B 2 163 ? -0.40000  21.92200 9.07300   1.000 32.55939  ? 163 GLU   L C   1 
ATOM   2887 O  O   . GLU   B 2 163 ? -0.28500  22.40600 7.94500   1.000 32.70707  ? 163 GLU   L O   1 
ATOM   2888 C  CB  . GLU   B 2 163 ? -1.67600  23.11000 10.87800  1.000 33.72726  ? 163 GLU   L CB  1 
ATOM   2889 C  CG  . GLU   B 2 163 ? -1.68000  23.46100 12.36000  1.000 38.17193  ? 163 GLU   L CG  1 
ATOM   2890 C  CD  . GLU   B 2 163 ? -3.05100  23.86200 12.86600  1.000 42.35225  ? 163 GLU   L CD  1 
ATOM   2891 O  OE1 . GLU   B 2 163 ? -4.03700  23.67700 12.12300  1.000 41.49935  ? 163 GLU   L OE1 1 
ATOM   2892 O  OE2 . GLU   B 2 163 ? -3.14300  24.36100 14.00800  1.000 45.45289  ? 163 GLU   L OE2 1 
ATOM   2893 N  N   . SER   B 2 164 ? -0.62000  20.62600 9.29000   1.000 39.94548  ? 164 SER   L N   1 
ATOM   2894 C  CA  . SER   B 2 164 ? -0.76300  19.66000 8.20800   1.000 33.78865  ? 164 SER   L CA  1 
ATOM   2895 C  C   . SER   B 2 164 ? -1.68000  18.54600 8.69000   1.000 33.91567  ? 164 SER   L C   1 
ATOM   2896 O  O   . SER   B 2 164 ? -1.52300  18.06000 9.81300   1.000 33.61554  ? 164 SER   L O   1 
ATOM   2897 C  CB  . SER   B 2 164 ? 0.59800   19.10100 7.78400   1.000 33.87369  ? 164 SER   L CB  1 
ATOM   2898 O  OG  . SER   B 2 164 ? 0.52800   18.49500 6.50600   1.000 32.68538  ? 164 SER   L OG  1 
ATOM   2899 N  N   . VAL   B 2 165 ? -2.63300  18.14900 7.84600   1.000 33.47015  ? 165 VAL   L N   1 
ATOM   2900 C  CA  . VAL   B 2 165 ? -3.72200  17.26700 8.25000   1.000 31.11202  ? 165 VAL   L CA  1 
ATOM   2901 C  C   . VAL   B 2 165 ? -3.82500  16.09500 7.28500   1.000 33.39789  ? 165 VAL   L C   1 
ATOM   2902 O  O   . VAL   B 2 165 ? -3.72200  16.26700 6.06500   1.000 33.86215  ? 165 VAL   L O   1 
ATOM   2903 C  CB  . VAL   B 2 165 ? -5.06200  18.02900 8.31500   1.000 33.29399  ? 165 VAL   L CB  1 
ATOM   2904 C  CG1 . VAL   B 2 165 ? -6.17800  17.11600 8.79300   1.000 29.56393  ? 165 VAL   L CG1 1 
ATOM   2905 C  CG2 . VAL   B 2 165 ? -4.93500  19.23300 9.22200   1.000 39.45685  ? 165 VAL   L CG2 1 
ATOM   2906 N  N   . THR   B 2 166 ? -4.03800  14.90300 7.83800   1.000 31.34338  ? 166 THR   L N   1 
ATOM   2907 C  CA  . THR   B 2 166 ? -4.31400  13.71900 7.04400   1.000 32.74828  ? 166 THR   L CA  1 
ATOM   2908 C  C   . THR   B 2 166 ? -5.75500  13.74400 6.54500   1.000 36.10665  ? 166 THR   L C   1 
ATOM   2909 O  O   . THR   B 2 166 ? -6.61000  14.46500 7.06600   1.000 40.57062  ? 166 THR   L O   1 
ATOM   2910 C  CB  . THR   B 2 166 ? -4.08400  12.45000 7.86500   1.000 35.51337  ? 166 THR   L CB  1 
ATOM   2911 O  OG1 . THR   B 2 166 ? -4.99700  12.42300 8.97000   1.000 37.74495  ? 166 THR   L OG1 1 
ATOM   2912 C  CG2 . THR   B 2 166 ? -2.66100  12.40700 8.39600   1.000 32.42366  ? 166 THR   L CG2 1 
ATOM   2913 N  N   . GLU   B 2 167 ? -6.02200  12.94300 5.52000   1.000 40.91303  ? 167 GLU   L N   1 
ATOM   2914 C  CA  . GLU   B 2 167 ? -7.39800  12.76600 5.09200   1.000 44.57685  ? 167 GLU   L CA  1 
ATOM   2915 C  C   . GLU   B 2 167 ? -8.13200  11.88100 6.09900   1.000 44.65656  ? 167 GLU   L C   1 
ATOM   2916 O  O   . GLU   B 2 167 ? -7.52800  11.24200 6.96700   1.000 53.55271  ? 167 GLU   L O   1 
ATOM   2917 C  CB  . GLU   B 2 167 ? -7.44100  12.17800 3.67700   1.000 49.46902  ? 167 GLU   L CB  1 
ATOM   2918 C  CG  . GLU   B 2 167 ? -8.80400  12.15400 2.94800   1.000 62.15222  ? 167 GLU   L CG  1 
ATOM   2919 C  CD  . GLU   B 2 167 ? -9.78100  13.25100 3.36400   1.000 62.63753  ? 167 GLU   L CD  1 
ATOM   2920 O  OE1 . GLU   B 2 167 ? -9.38800  14.43600 3.47500   1.000 54.45768  ? 167 GLU   L OE1 1 
ATOM   2921 O  OE2 . GLU   B 2 167 ? -10.95900 12.90600 3.59700   1.000 57.55470  ? 167 GLU   L OE2 1 
ATOM   2922 N  N   . GLN   B 2 168 ? -9.45700  11.87300 5.99200   1.000 40.08923  ? 168 GLN   L N   1 
ATOM   2923 C  CA  . GLN   B 2 168 ? -10.27800 11.01700 6.83300   1.000 41.28062  ? 168 GLN   L CA  1 
ATOM   2924 C  C   . GLN   B 2 168 ? -9.81600  9.57000  6.72600   1.000 45.25656  ? 168 GLN   L C   1 
ATOM   2925 O  O   . GLN   B 2 168 ? -9.71200  9.01800  5.62700   1.000 51.13124  ? 168 GLN   L O   1 
ATOM   2926 C  CB  . GLN   B 2 168 ? -11.74400 11.13900 6.42200   1.000 43.79466  ? 168 GLN   L CB  1 
ATOM   2927 C  CG  . GLN   B 2 168 ? -12.72700 11.07100 7.57200   1.000 45.08131  ? 168 GLN   L CG  1 
ATOM   2928 C  CD  . GLN   B 2 168 ? -13.95400 11.92700 7.33600   1.000 44.37244  ? 168 GLN   L CD  1 
ATOM   2929 O  OE1 . GLN   B 2 168 ? -14.18800 12.40300 6.22500   1.000 47.05931  ? 168 GLN   L OE1 1 
ATOM   2930 N  NE2 . GLN   B 2 168 ? -14.74400 12.13100 8.38400   1.000 43.38049  ? 168 GLN   L NE2 1 
ATOM   2931 N  N   . ASP   B 2 169 ? -9.50700  8.97200  7.87400   1.000 45.17497  ? 169 ASP   L N   1 
ATOM   2932 C  CA  . ASP   B 2 169 ? -9.13800  7.56400  7.92100   1.000 45.52521  ? 169 ASP   L CA  1 
ATOM   2933 C  C   . ASP   B 2 169 ? -10.22800 6.71700  7.27600   1.000 54.67509  ? 169 ASP   L C   1 
ATOM   2934 O  O   . ASP   B 2 169 ? -11.42000 7.00000  7.41000   1.000 57.62706  ? 169 ASP   L O   1 
ATOM   2935 C  CB  . ASP   B 2 169 ? -8.91500  7.14800  9.37700   1.000 49.87960  ? 169 ASP   L CB  1 
ATOM   2936 C  CG  . ASP   B 2 169 ? -8.37600  5.73200  9.52500   1.000 60.27408  ? 169 ASP   L CG  1 
ATOM   2937 O  OD1 . ASP   B 2 169 ? -8.44500  4.93500  8.56600   1.000 60.36940  ? 169 ASP   L OD1 1 
ATOM   2938 O  OD2 . ASP   B 2 169 ? -7.87500  5.41500  10.62500  1.000 58.39316  ? 169 ASP   L OD2 1 
ATOM   2939 N  N   . SER   B 2 170 ? -9.81500  5.67900  6.54900   1.000 58.13834  ? 170 SER   L N   1 
ATOM   2940 C  CA  . SER   B 2 170 ? -10.80200 4.81500  5.91200   1.000 59.22067  ? 170 SER   L CA  1 
ATOM   2941 C  C   . SER   B 2 170 ? -11.49200 3.92200  6.93700   1.000 61.78981  ? 170 SER   L C   1 
ATOM   2942 O  O   . SER   B 2 170 ? -12.69700 3.66300  6.83300   1.000 58.14176  ? 170 SER   L O   1 
ATOM   2943 C  CB  . SER   B 2 170 ? -10.14300 3.98500  4.81100   1.000 55.82551  ? 170 SER   L CB  1 
ATOM   2944 O  OG  . SER   B 2 170 ? -10.13700 4.69800  3.58400   1.000 56.60195  ? 170 SER   L OG  1 
ATOM   2945 N  N   . LYS   B 2 171 ? -10.75200 3.46300  7.94500   1.000 62.36619  ? 171 LYS   L N   1 
ATOM   2946 C  CA  . LYS   B 2 171 ? -11.31900 2.60900  8.98000   1.000 58.47187  ? 171 LYS   L CA  1 
ATOM   2947 C  C   . LYS   B 2 171 ? -12.27900 3.38000  9.87700   1.000 56.88307  ? 171 LYS   L C   1 
ATOM   2948 O  O   . LYS   B 2 171 ? -13.49000 3.14300  9.84200   1.000 58.52337  ? 171 LYS   L O   1 
ATOM   2949 C  CB  . LYS   B 2 171 ? -10.20500 1.98000  9.82000   1.000 60.01877  ? 171 LYS   L CB  1 
ATOM   2950 N  N   . ASP   B 2 172 ? -11.75300 4.29800  10.68700  1.000 54.18262  ? 172 ASP   L N   1 
ATOM   2951 C  CA  . ASP   B 2 172 ? -12.54700 4.95700  11.71600  1.000 48.97590  ? 172 ASP   L CA  1 
ATOM   2952 C  C   . ASP   B 2 172 ? -12.94100 6.38700  11.36800  1.000 51.02315  ? 172 ASP   L C   1 
ATOM   2953 O  O   . ASP   B 2 172 ? -13.56600 7.05100  12.19700  1.000 46.08523  ? 172 ASP   L O   1 
ATOM   2954 C  CB  . ASP   B 2 172 ? -11.80000 4.93100  13.05800  1.000 54.76844  ? 172 ASP   L CB  1 
ATOM   2955 C  CG  . ASP   B 2 172 ? -10.51400 5.74900  13.04400  1.000 55.40756  ? 172 ASP   L CG  1 
ATOM   2956 O  OD1 . ASP   B 2 172 ? -10.18900 6.37200  12.01500  1.000 53.25541  ? 172 ASP   L OD1 1 
ATOM   2957 O  OD2 . ASP   B 2 172 ? -9.81300  5.76000  14.07700  1.000 51.73395  ? 172 ASP   L OD2 1 
ATOM   2958 N  N   . SER   B 2 173 ? -12.58000 6.87900  10.17800  1.000 49.97637  ? 173 SER   L N   1 
ATOM   2959 C  CA  . SER   B 2 173 ? -12.99900 8.20000  9.69600   1.000 46.18630  ? 173 SER   L CA  1 
ATOM   2960 C  C   . SER   B 2 173 ? -12.53800 9.33100  10.61200  1.000 44.37778  ? 173 SER   L C   1 
ATOM   2961 O  O   . SER   B 2 173 ? -13.25500 10.31700 10.81100  1.000 38.79740  ? 173 SER   L O   1 
ATOM   2962 C  CB  . SER   B 2 173 ? -14.51600 8.26000  9.49200   1.000 42.70129  ? 173 SER   L CB  1 
ATOM   2963 O  OG  . SER   B 2 173 ? -15.01200 7.05300  8.93500   1.000 57.11115  ? 173 SER   L OG  1 
ATOM   2964 N  N   . THR   B 2 174 ? -11.34400 9.20600  11.17500  1.000 45.09916  ? 174 THR   L N   1 
ATOM   2965 C  CA  . THR   B 2 174 ? -10.76400 10.26700 11.98100  1.000 39.98217  ? 174 THR   L CA  1 
ATOM   2966 C  C   . THR   B 2 174 ? -9.74600  11.07000 11.17800  1.000 39.64932  ? 174 THR   L C   1 
ATOM   2967 O  O   . THR   B 2 174 ? -9.34900  10.70700 10.06700  1.000 41.71161  ? 174 THR   L O   1 
ATOM   2968 C  CB  . THR   B 2 174 ? -10.09900 9.69700  13.23700  1.000 44.21219  ? 174 THR   L CB  1 
ATOM   2969 O  OG1 . THR   B 2 174 ? -9.00700  8.84800  12.85900  1.000 45.39720  ? 174 THR   L OG1 1 
ATOM   2970 C  CG2 . THR   B 2 174 ? -11.10800 8.91300  14.07600  1.000 43.88313  ? 174 THR   L CG2 1 
ATOM   2971 N  N   . TYR   B 2 175 ? -9.32900  12.18400 11.76800  1.000 43.14763  ? 175 TYR   L N   1 
ATOM   2972 C  CA  . TYR   B 2 175 ? -8.22000  12.98300 11.27500  1.000 37.92704  ? 175 TYR   L CA  1 
ATOM   2973 C  C   . TYR   B 2 175 ? -7.06300  12.93500 12.26400  1.000 41.16103  ? 175 TYR   L C   1 
ATOM   2974 O  O   . TYR   B 2 175 ? -7.24900  12.73400 13.46600  1.000 40.40002  ? 175 TYR   L O   1 
ATOM   2975 C  CB  . TYR   B 2 175 ? -8.62700  14.44500 11.06400  1.000 34.38653  ? 175 TYR   L CB  1 
ATOM   2976 C  CG  . TYR   B 2 175 ? -9.80500  14.66200 10.15300  1.000 38.73007  ? 175 TYR   L CG  1 
ATOM   2977 C  CD1 . TYR   B 2 175 ? -9.63700  14.77700 8.78000   1.000 39.93898  ? 175 TYR   L CD1 1 
ATOM   2978 C  CD2 . TYR   B 2 175 ? -11.08600 14.77300 10.67000  1.000 38.46490  ? 175 TYR   L CD2 1 
ATOM   2979 C  CE1 . TYR   B 2 175 ? -10.71400 14.98700 7.94700   1.000 41.13403  ? 175 TYR   L CE1 1 
ATOM   2980 C  CE2 . TYR   B 2 175 ? -12.17000 14.98200 9.84600   1.000 37.95390  ? 175 TYR   L CE2 1 
ATOM   2981 C  CZ  . TYR   B 2 175 ? -11.97700 15.08800 8.48600   1.000 42.58203  ? 175 TYR   L CZ  1 
ATOM   2982 O  OH  . TYR   B 2 175 ? -13.04400 15.29700 7.65000   1.000 48.54227  ? 175 TYR   L OH  1 
ATOM   2983 N  N   . SER   B 2 176 ? -5.86000  13.14100 11.74000  1.000 37.48892  ? 176 SER   L N   1 
ATOM   2984 C  CA  . SER   B 2 176 ? -4.67300  13.32900 12.55800  1.000 36.43202  ? 176 SER   L CA  1 
ATOM   2985 C  C   . SER   B 2 176 ? -3.92300  14.55300 12.05600  1.000 35.50579  ? 176 SER   L C   1 
ATOM   2986 O  O   . SER   B 2 176 ? -3.83600  14.78200 10.84600  1.000 35.61062  ? 176 SER   L O   1 
ATOM   2987 C  CB  . SER   B 2 176 ? -3.78000  12.08700 12.54700  1.000 40.00765  ? 176 SER   L CB  1 
ATOM   2988 O  OG  . SER   B 2 176 ? -4.54600  10.90600 12.74600  1.000 52.46891  ? 176 SER   L OG  1 
ATOM   2989 N  N   . LEU   B 2 177 ? -3.40400  15.35100 12.98800  1.000 37.37146  ? 177 LEU   L N   1 
ATOM   2990 C  CA  . LEU   B 2 177 ? -2.91000  16.68100 12.66600  1.000 34.56945  ? 177 LEU   L CA  1 
ATOM   2991 C  C   . LEU   B 2 177 ? -1.46300  16.84800 13.10400  1.000 34.89537  ? 177 LEU   L C   1 
ATOM   2992 O  O   . LEU   B 2 177 ? -1.07700  16.42200 14.19600  1.000 32.76419  ? 177 LEU   L O   1 
ATOM   2993 C  CB  . LEU   B 2 177 ? -3.77800  17.75300 13.32900  1.000 37.14300  ? 177 LEU   L CB  1 
ATOM   2994 C  CG  . LEU   B 2 177 ? -3.35300  19.21200 13.16600  1.000 33.78826  ? 177 LEU   L CG  1 
ATOM   2995 C  CD1 . LEU   B 2 177 ? -4.53300  20.06200 12.73900  1.000 35.47755  ? 177 LEU   L CD1 1 
ATOM   2996 C  CD2 . LEU   B 2 177 ? -2.75100  19.74300 14.45500  1.000 36.12408  ? 177 LEU   L CD2 1 
ATOM   2997 N  N   . SER   B 2 178 ? -0.67100  17.47900 12.24400  1.000 37.92698  ? 178 SER   L N   1 
ATOM   2998 C  CA  . SER   B 2 178 ? 0.68500   17.89200 12.57100  1.000 33.67011  ? 178 SER   L CA  1 
ATOM   2999 C  C   . SER   B 2 178 ? 0.74500   19.41000 12.67500  1.000 39.58920  ? 178 SER   L C   1 
ATOM   3000 O  O   . SER   B 2 178 ? 0.05800   20.12000 11.93500  1.000 37.57621  ? 178 SER   L O   1 
ATOM   3001 C  CB  . SER   B 2 178 ? 1.68000   17.40100 11.52100  1.000 32.12380  ? 178 SER   L CB  1 
ATOM   3002 O  OG  . SER   B 2 178 ? 2.75600   18.31300 11.38300  1.000 46.38394  ? 178 SER   L OG  1 
ATOM   3003 N  N   . SER   B 2 179 ? 1.56100   19.90300 13.60400  1.000 39.13273  ? 179 SER   L N   1 
ATOM   3004 C  CA  . SER   B 2 179 ? 1.80300   21.33400 13.75400  1.000 33.56456  ? 179 SER   L CA  1 
ATOM   3005 C  C   . SER   B 2 179 ? 3.26300   21.51000 14.13000  1.000 31.83772  ? 179 SER   L C   1 
ATOM   3006 O  O   . SER   B 2 179 ? 3.68200   21.07800 15.20700  1.000 31.30434  ? 179 SER   L O   1 
ATOM   3007 C  CB  . SER   B 2 179 ? 0.89000   21.96700 14.81100  1.000 36.45199  ? 179 SER   L CB  1 
ATOM   3008 O  OG  . SER   B 2 179 ? 1.28900   23.30200 15.08600  1.000 39.30952  ? 179 SER   L OG  1 
ATOM   3009 N  N   . THR   B 2 180 ? 4.03200   22.13500 13.24500  1.000 31.90694  ? 180 THR   L N   1 
ATOM   3010 C  CA  . THR   B 2 180 ? 5.47600   22.26600 13.40300  1.000 32.29732  ? 180 THR   L CA  1 
ATOM   3011 C  C   . THR   B 2 180 ? 5.82600   23.71700 13.71300  1.000 35.79594  ? 180 THR   L C   1 
ATOM   3012 O  O   . THR   B 2 180 ? 5.57100   24.61100 12.89800  1.000 33.82574  ? 180 THR   L O   1 
ATOM   3013 C  CB  . THR   B 2 180 ? 6.20700   21.79300 12.14600  1.000 29.52320  ? 180 THR   L CB  1 
ATOM   3014 O  OG1 . THR   B 2 180 ? 5.67800   20.52500 11.73500  1.000 34.29811  ? 180 THR   L OG1 1 
ATOM   3015 C  CG2 . THR   B 2 180 ? 7.69600   21.65000 12.41400  1.000 32.49820  ? 180 THR   L CG2 1 
ATOM   3016 N  N   . LEU   B 2 181 ? 6.40400   23.94500 14.89100  1.000 41.14735  ? 181 LEU   L N   1 
ATOM   3017 C  CA  . LEU   B 2 181 ? 6.85700   25.26600 15.31000  1.000 36.64391  ? 181 LEU   L CA  1 
ATOM   3018 C  C   . LEU   B 2 181 ? 8.34600   25.38600 15.00800  1.000 39.87130  ? 181 LEU   L C   1 
ATOM   3019 O  O   . LEU   B 2 181 ? 9.15800   24.63200 15.55700  1.000 39.21903  ? 181 LEU   L O   1 
ATOM   3020 C  CB  . LEU   B 2 181 ? 6.58300   25.49000 16.79700  1.000 37.03753  ? 181 LEU   L CB  1 
ATOM   3021 C  CG  . LEU   B 2 181 ? 7.24000   26.70600 17.45100  1.000 39.75931  ? 181 LEU   L CG  1 
ATOM   3022 C  CD1 . LEU   B 2 181 ? 6.50900   27.98000 17.06700  1.000 38.46620  ? 181 LEU   L CD1 1 
ATOM   3023 C  CD2 . LEU   B 2 181 ? 7.27700   26.54800 18.96300  1.000 42.42824  ? 181 LEU   L CD2 1 
ATOM   3024 N  N   . THR   B 2 182 ? 8.70000   26.32900 14.14000  1.000 42.26164  ? 182 THR   L N   1 
ATOM   3025 C  CA  . THR   B 2 182 ? 10.05900  26.47500 13.63700  1.000 42.73517  ? 182 THR   L CA  1 
ATOM   3026 C  C   . THR   B 2 182 ? 10.74200  27.64900 14.32500  1.000 41.22244  ? 182 THR   L C   1 
ATOM   3027 O  O   . THR   B 2 182 ? 10.19700  28.75700 14.36000  1.000 48.48153  ? 182 THR   L O   1 
ATOM   3028 C  CB  . THR   B 2 182 ? 10.05400  26.67700 12.11900  1.000 44.88053  ? 182 THR   L CB  1 
ATOM   3029 O  OG1 . THR   B 2 182 ? 9.65600   25.45800 11.48000  1.000 44.07727  ? 182 THR   L OG1 1 
ATOM   3030 C  CG2 . THR   B 2 182 ? 11.43800  27.07400 11.62200  1.000 39.18666  ? 182 THR   L CG2 1 
ATOM   3031 N  N   . LEU   B 2 183 ? 11.93600  27.40400 14.86200  1.000 38.32574  ? 183 LEU   L N   1 
ATOM   3032 C  CA  . LEU   B 2 183 ? 12.69700  28.42100 15.57100  1.000 40.20737  ? 183 LEU   L CA  1 
ATOM   3033 C  C   . LEU   B 2 183 ? 14.15300  28.36700 15.13300  1.000 40.49112  ? 183 LEU   L C   1 
ATOM   3034 O  O   . LEU   B 2 183 ? 14.60000  27.41600 14.48500  1.000 42.63685  ? 183 LEU   L O   1 
ATOM   3035 C  CB  . LEU   B 2 183 ? 12.61200  28.23800 17.09100  1.000 46.58565  ? 183 LEU   L CB  1 
ATOM   3036 C  CG  . LEU   B 2 183 ? 11.23600  28.23000 17.75400  1.000 42.25280  ? 183 LEU   L CG  1 
ATOM   3037 C  CD1 . LEU   B 2 183 ? 11.37300  27.95700 19.24300  1.000 44.46140  ? 183 LEU   L CD1 1 
ATOM   3038 C  CD2 . LEU   B 2 183 ? 10.52000  29.54700 17.51100  1.000 47.20099  ? 183 LEU   L CD2 1 
ATOM   3039 N  N   . SER   B 2 184 ? 14.89300  29.40800 15.49700  1.000 43.49769  ? 184 SER   L N   1 
ATOM   3040 C  CA  . SER   B 2 184 ? 16.33700  29.39700 15.35000  1.000 45.87005  ? 184 SER   L CA  1 
ATOM   3041 C  C   . SER   B 2 184 ? 16.96600  28.60200 16.48800  1.000 49.72179  ? 184 SER   L C   1 
ATOM   3042 O  O   . SER   B 2 184 ? 16.36100  28.39600 17.54200  1.000 51.25334  ? 184 SER   L O   1 
ATOM   3043 C  CB  . SER   B 2 184 ? 16.89000  30.82400 15.34500  1.000 47.55961  ? 184 SER   L CB  1 
ATOM   3044 O  OG  . SER   B 2 184 ? 16.36300  31.57600 16.42600  1.000 52.85610  ? 184 SER   L OG  1 
ATOM   3045 N  N   . LYS   B 2 185 ? 18.20000  28.14600 16.26400  1.000 46.09992  ? 185 LYS   L N   1 
ATOM   3046 C  CA  . LYS   B 2 185 ? 18.97000  27.56000 17.35600  1.000 45.49186  ? 185 LYS   L CA  1 
ATOM   3047 C  C   . LYS   B 2 185 ? 19.14100  28.54500 18.50500  1.000 53.80175  ? 185 LYS   L C   1 
ATOM   3048 O  O   . LYS   B 2 185 ? 19.23600  28.13600 19.66700  1.000 59.84135  ? 185 LYS   L O   1 
ATOM   3049 C  CB  . LYS   B 2 185 ? 20.33400  27.10600 16.84100  1.000 48.94667  ? 185 LYS   L CB  1 
ATOM   3050 C  CG  . LYS   B 2 185 ? 21.18300  26.34000 17.83600  1.000 52.06117  ? 185 LYS   L CG  1 
ATOM   3051 C  CD  . LYS   B 2 185 ? 22.42700  25.82300 17.13400  1.000 55.58154  ? 185 LYS   L CD  1 
ATOM   3052 C  CE  . LYS   B 2 185 ? 23.68700  25.95800 17.97100  1.000 66.37665  ? 185 LYS   L CE  1 
ATOM   3053 N  NZ  . LYS   B 2 185 ? 23.77200  24.90900 19.02500  1.000 76.30166  ? 185 LYS   L NZ  1 
ATOM   3054 N  N   . ALA   B 2 186 ? 19.16800  29.84400 18.20000  1.000 52.10155  ? 186 ALA   L N   1 
ATOM   3055 C  CA  . ALA   B 2 186 ? 19.36600  30.88600 19.20000  1.000 48.47433  ? 186 ALA   L CA  1 
ATOM   3056 C  C   . ALA   B 2 186 ? 18.13900  31.06100 20.08700  1.000 56.26082  ? 186 ALA   L C   1 
ATOM   3057 O  O   . ALA   B 2 186 ? 18.20800  30.83100 21.29900  1.000 61.81169  ? 186 ALA   L O   1 
ATOM   3058 C  CB  . ALA   B 2 186 ? 19.71400  32.21000 18.51800  1.000 51.59899  ? 186 ALA   L CB  1 
ATOM   3059 N  N   . ASP   B 2 187 ? 17.01400  31.47600 19.49500  1.000 55.50919  ? 187 ASP   L N   1 
ATOM   3060 C  CA  . ASP   B 2 187 ? 15.79900  31.67100 20.28200  1.000 55.36936  ? 187 ASP   L CA  1 
ATOM   3061 C  C   . ASP   B 2 187 ? 15.34100  30.37500 20.93600  1.000 56.35712  ? 187 ASP   L C   1 
ATOM   3062 O  O   . ASP   B 2 187 ? 14.67300  30.40800 21.97500  1.000 59.86903  ? 187 ASP   L O   1 
ATOM   3063 C  CB  . ASP   B 2 187 ? 14.68200  32.24500 19.40900  1.000 54.06635  ? 187 ASP   L CB  1 
ATOM   3064 C  CG  . ASP   B 2 187 ? 13.45400  32.64400 20.21500  1.000 51.97998  ? 187 ASP   L CG  1 
ATOM   3065 O  OD1 . ASP   B 2 187 ? 13.59400  32.95400 21.41700  1.000 39.62018  ? 187 ASP   L OD1 1 
ATOM   3066 O  OD2 . ASP   B 2 187 ? 12.34400  32.64700 19.64600  1.000 50.28216  ? 187 ASP   L OD2 1 
ATOM   3067 N  N   . TYR   B 2 188 ? 15.68800  29.22700 20.34800  1.000 55.14064  ? 188 TYR   L N   1 
ATOM   3068 C  CA  . TYR   B 2 188 ? 15.34600  27.95600 20.97600  1.000 57.09192  ? 188 TYR   L CA  1 
ATOM   3069 C  C   . TYR   B 2 188 ? 16.08400  27.77400 22.29600  1.000 59.69117  ? 188 TYR   L C   1 
ATOM   3070 O  O   . TYR   B 2 188 ? 15.49600  27.32800 23.28800  1.000 64.00012  ? 188 TYR   L O   1 
ATOM   3071 C  CB  . TYR   B 2 188 ? 15.65500  26.78700 20.04300  1.000 54.65402  ? 188 TYR   L CB  1 
ATOM   3072 C  CG  . TYR   B 2 188 ? 15.46800  25.44400 20.70800  1.000 57.77331  ? 188 TYR   L CG  1 
ATOM   3073 C  CD1 . TYR   B 2 188 ? 14.21100  25.02600 21.12400  1.000 54.23692  ? 188 TYR   L CD1 1 
ATOM   3074 C  CD2 . TYR   B 2 188 ? 16.54800  24.60200 20.94000  1.000 55.94931  ? 188 TYR   L CD2 1 
ATOM   3075 C  CE1 . TYR   B 2 188 ? 14.03100  23.80700 21.74300  1.000 50.10912  ? 188 TYR   L CE1 1 
ATOM   3076 C  CE2 . TYR   B 2 188 ? 16.37700  23.37800 21.55700  1.000 51.96291  ? 188 TYR   L CE2 1 
ATOM   3077 C  CZ  . TYR   B 2 188 ? 15.11700  22.98800 21.95900  1.000 51.61037  ? 188 TYR   L CZ  1 
ATOM   3078 O  OH  . TYR   B 2 188 ? 14.93800  21.77000 22.57300  1.000 48.53959  ? 188 TYR   L OH  1 
ATOM   3079 N  N   . GLU   B 2 189 ? 17.37000  28.10800 22.33500  1.000 59.59516  ? 189 GLU   L N   1 
ATOM   3080 C  CA  . GLU   B 2 189 ? 18.15600  27.87100 23.53700  1.000 62.82432  ? 189 GLU   L CA  1 
ATOM   3081 C  C   . GLU   B 2 189 ? 18.10000  29.02400 24.53200  1.000 60.77813  ? 189 GLU   L C   1 
ATOM   3082 O  O   . GLU   B 2 189 ? 18.58300  28.87000 25.65900  1.000 62.83759  ? 189 GLU   L O   1 
ATOM   3083 C  CB  . GLU   B 2 189 ? 19.60800  27.56300 23.15700  1.000 60.25962  ? 189 GLU   L CB  1 
ATOM   3084 C  CG  . GLU   B 2 189 ? 19.80100  26.11600 22.71700  1.000 61.81049  ? 189 GLU   L CG  1 
ATOM   3085 C  CD  . GLU   B 2 189 ? 21.07000  25.90200 21.92000  1.000 69.91398  ? 189 GLU   L CD  1 
ATOM   3086 O  OE1 . GLU   B 2 189 ? 21.35100  24.74200 21.55000  1.000 73.69539  ? 189 GLU   L OE1 1 
ATOM   3087 O  OE2 . GLU   B 2 189 ? 21.78700  26.89200 21.66400  1.000 65.97104  ? 189 GLU   L OE2 1 
ATOM   3088 N  N   . LYS   B 2 190 ? 17.51400  30.16000 24.15600  1.000 59.41141  ? 190 LYS   L N   1 
ATOM   3089 C  CA  . LYS   B 2 190 ? 17.26200  31.25200 25.08600  1.000 63.37900  ? 190 LYS   L CA  1 
ATOM   3090 C  C   . LYS   B 2 190 ? 15.93200  31.09900 25.81800  1.000 63.95752  ? 190 LYS   L C   1 
ATOM   3091 O  O   . LYS   B 2 190 ? 15.50900  32.02800 26.51400  1.000 68.27623  ? 190 LYS   L O   1 
ATOM   3092 C  CB  . LYS   B 2 190 ? 17.30600  32.59500 24.34900  1.000 53.04592  ? 190 LYS   L CB  1 
ATOM   3093 N  N   . HIS   B 2 191 ? 15.26900  29.95300 25.67000  1.000 64.06563  ? 191 HIS   L N   1 
ATOM   3094 C  CA  . HIS   B 2 191 ? 14.02200  29.63800 26.35400  1.000 61.45811  ? 191 HIS   L CA  1 
ATOM   3095 C  C   . HIS   B 2 191 ? 14.15000  28.27300 27.01500  1.000 58.53206  ? 191 HIS   L C   1 
ATOM   3096 O  O   . HIS   B 2 191 ? 15.12700  27.54800 26.81000  1.000 52.41721  ? 191 HIS   L O   1 
ATOM   3097 C  CB  . HIS   B 2 191 ? 12.83100  29.64200 25.39000  1.000 57.98640  ? 191 HIS   L CB  1 
ATOM   3098 C  CG  . HIS   B 2 191 ? 12.46500  31.00200 24.88500  1.000 59.42840  ? 191 HIS   L CG  1 
ATOM   3099 N  ND1 . HIS   B 2 191 ? 12.15700  32.05000 25.72400  1.000 59.08349  ? 191 HIS   L ND1 1 
ATOM   3100 C  CD2 . HIS   B 2 191 ? 12.34700  31.48100 23.62500  1.000 60.90097  ? 191 HIS   L CD2 1 
ATOM   3101 C  CE1 . HIS   B 2 191 ? 11.87000  33.11900 25.00200  1.000 63.33163  ? 191 HIS   L CE1 1 
ATOM   3102 N  NE2 . HIS   B 2 191 ? 11.97700  32.80000 23.72500  1.000 61.06265  ? 191 HIS   L NE2 1 
ATOM   3103 N  N   . LYS   B 2 192 ? 13.14000  27.90800 27.80500  1.000 60.51353  ? 192 LYS   L N   1 
ATOM   3104 C  CA  . LYS   B 2 192 ? 13.20300  26.63300 28.50900  1.000 61.48312  ? 192 LYS   L CA  1 
ATOM   3105 C  C   . LYS   B 2 192 ? 11.95200  25.77900 28.30900  1.000 55.03475  ? 192 LYS   L C   1 
ATOM   3106 O  O   . LYS   B 2 192 ? 12.05700  24.61000 27.92500  1.000 57.45086  ? 192 LYS   L O   1 
ATOM   3107 C  CB  . LYS   B 2 192 ? 13.45600  26.86500 30.00400  1.000 61.49607  ? 192 LYS   L CB  1 
ATOM   3108 C  CG  . LYS   B 2 192 ? 13.64000  25.57400 30.78100  1.000 59.92202  ? 192 LYS   L CG  1 
ATOM   3109 C  CD  . LYS   B 2 192 ? 13.70700  25.79200 32.28100  1.000 70.13145  ? 192 LYS   L CD  1 
ATOM   3110 C  CE  . LYS   B 2 192 ? 12.36900  26.25600 32.82100  1.000 71.31284  ? 192 LYS   L CE  1 
ATOM   3111 N  NZ  . LYS   B 2 192 ? 12.19100  25.95100 34.26500  1.000 62.43823  ? 192 LYS   L NZ  1 
ATOM   3112 N  N   . VAL   B 2 193 ? 10.77000  26.33600 28.56300  1.000 54.24461  ? 193 VAL   L N   1 
ATOM   3113 C  CA  . VAL   B 2 193 ? 9.52600   25.57100 28.56200  1.000 56.96001  ? 193 VAL   L CA  1 
ATOM   3114 C  C   . VAL   B 2 193 ? 8.81900   25.76400 27.22600  1.000 53.40430  ? 193 VAL   L C   1 
ATOM   3115 O  O   . VAL   B 2 193 ? 8.44100   26.88700 26.87000  1.000 49.17125  ? 193 VAL   L O   1 
ATOM   3116 C  CB  . VAL   B 2 193 ? 8.61300   25.98600 29.72600  1.000 57.74887  ? 193 VAL   L CB  1 
ATOM   3117 C  CG1 . VAL   B 2 193 ? 7.27600   25.26900 29.62800  1.000 52.70503  ? 193 VAL   L CG1 1 
ATOM   3118 C  CG2 . VAL   B 2 193 ? 9.28500   25.69700 31.06000  1.000 57.18768  ? 193 VAL   L CG2 1 
ATOM   3119 N  N   . TYR   B 2 194 ? 8.63300   24.66700 26.49300  1.000 51.84863  ? 194 TYR   L N   1 
ATOM   3120 C  CA  . TYR   B 2 194 ? 7.91200   24.65100 25.22500  1.000 44.88710  ? 194 TYR   L CA  1 
ATOM   3121 C  C   . TYR   B 2 194 ? 6.65600   23.81400 25.39700  1.000 41.34695  ? 194 TYR   L C   1 
ATOM   3122 O  O   . TYR   B 2 194 ? 6.74500   22.61900 25.69600  1.000 48.53700  ? 194 TYR   L O   1 
ATOM   3123 C  CB  . TYR   B 2 194 ? 8.78200   24.08000 24.10600  1.000 38.53763  ? 194 TYR   L CB  1 
ATOM   3124 C  CG  . TYR   B 2 194 ? 10.03100  24.87900 23.87800  1.000 43.90636  ? 194 TYR   L CG  1 
ATOM   3125 C  CD1 . TYR   B 2 194 ? 11.16800  24.65900 24.64400  1.000 48.65316  ? 194 TYR   L CD1 1 
ATOM   3126 C  CD2 . TYR   B 2 194 ? 10.06900  25.87000 22.91200  1.000 51.93896  ? 194 TYR   L CD2 1 
ATOM   3127 C  CE1 . TYR   B 2 194 ? 12.30600  25.39800 24.44400  1.000 57.00498  ? 194 TYR   L CE1 1 
ATOM   3128 C  CE2 . TYR   B 2 194 ? 11.20200  26.60900 22.70300  1.000 55.15508  ? 194 TYR   L CE2 1 
ATOM   3129 C  CZ  . TYR   B 2 194 ? 12.31400  26.37100 23.47400  1.000 61.38314  ? 194 TYR   L CZ  1 
ATOM   3130 O  OH  . TYR   B 2 194 ? 13.44100  27.11200 23.27200  1.000 64.69920  ? 194 TYR   L OH  1 
ATOM   3131 N  N   . ALA   B 2 195 ? 5.49500   24.43300 25.20600  1.000 39.26310  ? 195 ALA   L N   1 
ATOM   3132 C  CA  . ALA   B 2 195 ? 4.21700   23.77400 25.41700  1.000 38.88410  ? 195 ALA   L CA  1 
ATOM   3133 C  C   . ALA   B 2 195 ? 3.38300   23.81600 24.14500  1.000 45.31237  ? 195 ALA   L C   1 
ATOM   3134 O  O   . ALA   B 2 195 ? 3.47500   24.75600 23.35000  1.000 46.47143  ? 195 ALA   L O   1 
ATOM   3135 C  CB  . ALA   B 2 195 ? 3.43900   24.42500 26.56500  1.000 43.96235  ? 195 ALA   L CB  1 
ATOM   3136 N  N   . CYS   B 2 196 ? 2.56500   22.78300 23.96300  1.000 49.92349  ? 196 CYS   L N   1 
ATOM   3137 C  CA  . CYS   B 2 196 ? 1.59300   22.72200 22.87900  1.000 47.87208  ? 196 CYS   L CA  1 
ATOM   3138 C  C   . CYS   B 2 196 ? 0.21400   22.54100 23.49500  1.000 49.17427  ? 196 CYS   L C   1 
ATOM   3139 O  O   . CYS   B 2 196 ? -0.02800  21.55500 24.19900  1.000 49.87352  ? 196 CYS   L O   1 
ATOM   3140 C  CB  . CYS   B 2 196 ? 1.91500   21.58500 21.90700  1.000 46.03326  ? 196 CYS   L CB  1 
ATOM   3141 S  SG  . CYS   B 2 196 ? 0.69400   21.33300 20.59500  1.000 73.04325  ? 196 CYS   L SG  1 
ATOM   3142 N  N   . GLU   B 2 197 ? -0.68000  23.49000 23.23400  1.000 45.52407  ? 197 GLU   L N   1 
ATOM   3143 C  CA  . GLU   B 2 197 ? -1.99600  23.53300 23.85800  1.000 45.58138  ? 197 GLU   L CA  1 
ATOM   3144 C  C   . GLU   B 2 197 ? -3.06100  23.22500 22.81400  1.000 49.30162  ? 197 GLU   L C   1 
ATOM   3145 O  O   . GLU   B 2 197 ? -3.22900  23.98100 21.85100  1.000 46.82571  ? 197 GLU   L O   1 
ATOM   3146 C  CB  . GLU   B 2 197 ? -2.24100  24.89800 24.50000  1.000 49.62674  ? 197 GLU   L CB  1 
ATOM   3147 C  CG  . GLU   B 2 197 ? -3.67400  25.14100 24.93600  1.000 59.24343  ? 197 GLU   L CG  1 
ATOM   3148 C  CD  . GLU   B 2 197 ? -4.09200  26.58800 24.76500  1.000 74.88628  ? 197 GLU   L CD  1 
ATOM   3149 O  OE1 . GLU   B 2 197 ? -3.43700  27.46800 25.36200  1.000 80.69674  ? 197 GLU   L OE1 1 
ATOM   3150 O  OE2 . GLU   B 2 197 ? -5.07100  26.84700 24.03400  1.000 74.43725  ? 197 GLU   L OE2 1 
ATOM   3151 N  N   . VAL   B 2 198 ? -3.78100  22.12200 23.01400  1.000 44.46316  ? 198 VAL   L N   1 
ATOM   3152 C  CA  . VAL   B 2 198 ? -4.79900  21.64700 22.08300  1.000 42.72346  ? 198 VAL   L CA  1 
ATOM   3153 C  C   . VAL   B 2 198 ? -6.17000  21.82500 22.71900  1.000 43.10210  ? 198 VAL   L C   1 
ATOM   3154 O  O   . VAL   B 2 198 ? -6.38600  21.42300 23.86900  1.000 49.28510  ? 198 VAL   L O   1 
ATOM   3155 C  CB  . VAL   B 2 198 ? -4.56600  20.17600 21.70000  1.000 43.41468  ? 198 VAL   L CB  1 
ATOM   3156 C  CG1 . VAL   B 2 198 ? -5.74200  19.64800 20.89400  1.000 43.54338  ? 198 VAL   L CG1 1 
ATOM   3157 C  CG2 . VAL   B 2 198 ? -3.26700  20.02800 20.92300  1.000 44.45119  ? 198 VAL   L CG2 1 
ATOM   3158 N  N   . THR   B 2 199 ? -7.09500  22.42700 21.97100  1.000 45.01257  ? 199 THR   L N   1 
ATOM   3159 C  CA  . THR   B 2 199 ? -8.48400  22.56900 22.39400  1.000 47.53501  ? 199 THR   L CA  1 
ATOM   3160 C  C   . THR   B 2 199 ? -9.37700  22.00400 21.29900  1.000 49.33395  ? 199 THR   L C   1 
ATOM   3161 O  O   . THR   B 2 199 ? -9.31200  22.45200 20.14900  1.000 48.17802  ? 199 THR   L O   1 
ATOM   3162 C  CB  . THR   B 2 199 ? -8.84200  24.03100 22.67800  1.000 46.94628  ? 199 THR   L CB  1 
ATOM   3163 O  OG1 . THR   B 2 199 ? -9.30300  24.65200 21.47300  1.000 49.85211  ? 199 THR   L OG1 1 
ATOM   3164 C  CG2 . THR   B 2 199 ? -7.63400  24.79700 23.19100  1.000 52.04509  ? 199 THR   L CG2 1 
ATOM   3165 N  N   . HIS   B 2 200 ? -10.21300 21.03200 21.65700  1.000 47.13852  ? 200 HIS   L N   1 
ATOM   3166 C  CA  . HIS   B 2 200 ? -11.03000 20.31200 20.69300  1.000 45.78410  ? 200 HIS   L CA  1 
ATOM   3167 C  C   . HIS   B 2 200 ? -12.41000 20.07200 21.29100  1.000 48.35900  ? 200 HIS   L C   1 
ATOM   3168 O  O   . HIS   B 2 200 ? -12.59600 20.11900 22.51000  1.000 56.10574  ? 200 HIS   L O   1 
ATOM   3169 C  CB  . HIS   B 2 200 ? -10.35700 18.98900 20.29300  1.000 47.44577  ? 200 HIS   L CB  1 
ATOM   3170 C  CG  . HIS   B 2 200 ? -11.14000 18.17700 19.31200  1.000 45.06947  ? 200 HIS   L CG  1 
ATOM   3171 N  ND1 . HIS   B 2 200 ? -11.95300 17.13200 19.69200  1.000 49.00860  ? 200 HIS   L ND1 1 
ATOM   3172 C  CD2 . HIS   B 2 200 ? -11.23600 18.25700 17.96400  1.000 46.29301  ? 200 HIS   L CD2 1 
ATOM   3173 C  CE1 . HIS   B 2 200 ? -12.51500 16.60200 18.62100  1.000 48.66492  ? 200 HIS   L CE1 1 
ATOM   3174 N  NE2 . HIS   B 2 200 ? -12.09700 17.26600 17.55900  1.000 47.26120  ? 200 HIS   L NE2 1 
ATOM   3175 N  N   . GLN   B 2 201 ? -13.38300 19.81800 20.41000  1.000 49.02807  ? 201 GLN   L N   1 
ATOM   3176 C  CA  . GLN   B 2 201 ? -14.77200 19.66400 20.83700  1.000 48.78741  ? 201 GLN   L CA  1 
ATOM   3177 C  C   . GLN   B 2 201 ? -14.92000 18.54400 21.86000  1.000 49.45747  ? 201 GLN   L C   1 
ATOM   3178 O  O   . GLN   B 2 201 ? -15.60800 18.70200 22.87500  1.000 54.96060  ? 201 GLN   L O   1 
ATOM   3179 C  CB  . GLN   B 2 201 ? -15.66400 19.40300 19.62200  1.000 55.75884  ? 201 GLN   L CB  1 
ATOM   3180 C  CG  . GLN   B 2 201 ? -17.11300 19.08200 19.96600  1.000 52.48805  ? 201 GLN   L CG  1 
ATOM   3181 C  CD  . GLN   B 2 201 ? -18.00800 19.03200 18.74200  1.000 63.25775  ? 201 GLN   L CD  1 
ATOM   3182 O  OE1 . GLN   B 2 201 ? -18.56500 17.98600 18.40800  1.000 67.67593  ? 201 GLN   L OE1 1 
ATOM   3183 N  NE2 . GLN   B 2 201 ? -18.15100 20.16600 18.06500  1.000 63.16463  ? 201 GLN   L NE2 1 
ATOM   3184 N  N   . GLY   B 2 202 ? -14.27900 17.40500 21.61300  1.000 53.73728  ? 202 GLY   L N   1 
ATOM   3185 C  CA  . GLY   B 2 202 ? -14.36500 16.28000 22.52300  1.000 56.24929  ? 202 GLY   L CA  1 
ATOM   3186 C  C   . GLY   B 2 202 ? -13.42000 16.38200 23.70200  1.000 54.19597  ? 202 GLY   L C   1 
ATOM   3187 O  O   . GLY   B 2 202 ? -12.94000 15.36600 24.21300  1.000 50.42766  ? 202 GLY   L O   1 
ATOM   3188 N  N   . LEU   B 2 203 ? -13.14800 17.60500 24.15000  1.000 52.82868  ? 203 LEU   L N   1 
ATOM   3189 C  CA  . LEU   B 2 203 ? -12.23600 17.85300 25.25900  1.000 56.59334  ? 203 LEU   L CA  1 
ATOM   3190 C  C   . LEU   B 2 203 ? -12.94000 18.73800 26.27300  1.000 59.22737  ? 203 LEU   L C   1 
ATOM   3191 O  O   . LEU   B 2 203 ? -13.36200 19.85100 25.93800  1.000 55.47504  ? 203 LEU   L O   1 
ATOM   3192 C  CB  . LEU   B 2 203 ? -10.94500 18.51100 24.77100  1.000 52.66578  ? 203 LEU   L CB  1 
ATOM   3193 C  CG  . LEU   B 2 203 ? -9.97200  17.55900 24.07700  1.000 48.61900  ? 203 LEU   L CG  1 
ATOM   3194 C  CD1 . LEU   B 2 203 ? -8.76600  18.31600 23.55700  1.000 45.65374  ? 203 LEU   L CD1 1 
ATOM   3195 C  CD2 . LEU   B 2 203 ? -9.55000  16.44400 25.01900  1.000 43.30859  ? 203 LEU   L CD2 1 
ATOM   3196 N  N   . SER   B 2 204 ? -13.07300 18.23400 27.50500  1.000 60.44309  ? 204 SER   L N   1 
ATOM   3197 C  CA  . SER   B 2 204 ? -13.67700 19.01800 28.57900  1.000 63.40554  ? 204 SER   L CA  1 
ATOM   3198 C  C   . SER   B 2 204 ? -13.03100 20.39000 28.68900  1.000 61.07333  ? 204 SER   L C   1 
ATOM   3199 O  O   . SER   B 2 204 ? -13.72100 21.40100 28.86100  1.000 66.73887  ? 204 SER   L O   1 
ATOM   3200 C  CB  . SER   B 2 204 ? -13.55700 18.26600 29.90400  1.000 69.87912  ? 204 SER   L CB  1 
ATOM   3201 O  OG  . SER   B 2 204 ? -12.20100 18.00700 30.21600  1.000 71.21335  ? 204 SER   L OG  1 
ATOM   3202 N  N   . SER   B 2 205 ? -11.70500 20.44200 28.58900  1.000 58.54738  ? 205 SER   L N   1 
ATOM   3203 C  CA  . SER   B 2 205 ? -10.96800 21.69600 28.59800  1.000 64.05389  ? 205 SER   L CA  1 
ATOM   3204 C  C   . SER   B 2 205 ? -9.61100  21.45600 27.95300  1.000 62.40699  ? 205 SER   L C   1 
ATOM   3205 O  O   . SER   B 2 205 ? -9.12400  20.31900 27.95600  1.000 60.21280  ? 205 SER   L O   1 
ATOM   3206 C  CB  . SER   B 2 205 ? -10.80800 22.23100 30.02800  1.000 65.70407  ? 205 SER   L CB  1 
ATOM   3207 O  OG  . SER   B 2 205 ? -10.02700 21.35500 30.82000  1.000 62.39721  ? 205 SER   L OG  1 
ATOM   3208 N  N   . PRO   B 2 206 ? -8.98200  22.50300 27.38300  1.000 56.39838  ? 206 PRO   L N   1 
ATOM   3209 C  CA  . PRO   B 2 206 ? -7.72400  22.33000 26.63800  1.000 49.70393  ? 206 PRO   L CA  1 
ATOM   3210 C  C   . PRO   B 2 206 ? -6.67200  21.43700 27.28400  1.000 51.84298  ? 206 PRO   L C   1 
ATOM   3211 O  O   . PRO   B 2 206 ? -6.45300  21.47600 28.50000  1.000 50.16739  ? 206 PRO   L O   1 
ATOM   3212 C  CB  . PRO   B 2 206 ? -7.20000  23.76900 26.51200  1.000 53.62062  ? 206 PRO   L CB  1 
ATOM   3213 C  CG  . PRO   B 2 206 ? -8.33400  24.68500 26.98700  1.000 56.73473  ? 206 PRO   L CG  1 
ATOM   3214 C  CD  . PRO   B 2 206 ? -9.55200  23.84100 27.16500  1.000 59.06132  ? 206 PRO   L CD  1 
ATOM   3215 N  N   . VAL   B 2 207 ? -6.01200  20.63000 26.45300  1.000 54.05486  ? 207 VAL   L N   1 
ATOM   3216 C  CA  . VAL   B 2 207 ? -4.91300  19.76300 26.86400  1.000 52.25470  ? 207 VAL   L CA  1 
ATOM   3217 C  C   . VAL   B 2 207 ? -3.59700  20.43400 26.50200  1.000 49.78914  ? 207 VAL   L C   1 
ATOM   3218 O  O   . VAL   B 2 207 ? -3.48100  21.08400 25.45400  1.000 52.14877  ? 207 VAL   L O   1 
ATOM   3219 C  CB  . VAL   B 2 207 ? -5.02500  18.37500 26.20400  1.000 42.64845  ? 207 VAL   L CB  1 
ATOM   3220 C  CG1 . VAL   B 2 207 ? -4.06900  17.39100 26.86200  1.000 39.57133  ? 207 VAL   L CG1 1 
ATOM   3221 C  CG2 . VAL   B 2 207 ? -6.45600  17.86700 26.28700  1.000 47.28839  ? 207 VAL   L CG2 1 
ATOM   3222 N  N   . THR   B 2 208 ? -2.59900  20.27900 27.37000  1.000 48.03994  ? 208 THR   L N   1 
ATOM   3223 C  CA  . THR   B 2 208 ? -1.28700  20.88200 27.16900  1.000 44.91411  ? 208 THR   L CA  1 
ATOM   3224 C  C   . THR   B 2 208 ? -0.21100  19.82100 27.34500  1.000 42.95724  ? 208 THR   L C   1 
ATOM   3225 O  O   . THR   B 2 208 ? -0.15000  19.16200 28.38700  1.000 46.52748  ? 208 THR   L O   1 
ATOM   3226 C  CB  . THR   B 2 208 ? -1.05400  22.04000 28.14300  1.000 54.54972  ? 208 THR   L CB  1 
ATOM   3227 O  OG1 . THR   B 2 208 ? -2.23300  22.85200 28.21100  1.000 55.95058  ? 208 THR   L OG1 1 
ATOM   3228 C  CG2 . THR   B 2 208 ? 0.11900   22.89500 27.68000  1.000 43.32752  ? 208 THR   L CG2 1 
ATOM   3229 N  N   . LYS   B 2 209 ? 0.62700   19.65600 26.32400  1.000 39.26007  ? 209 LYS   L N   1 
ATOM   3230 C  CA  . LYS   B 2 209 ? 1.81300   18.81500 26.38700  1.000 39.64746  ? 209 LYS   L CA  1 
ATOM   3231 C  C   . LYS   B 2 209 ? 3.04100   19.70200 26.24800  1.000 43.20598  ? 209 LYS   L C   1 
ATOM   3232 O  O   . LYS   B 2 209 ? 3.06900   20.60600 25.40700  1.000 42.17995  ? 209 LYS   L O   1 
ATOM   3233 C  CB  . LYS   B 2 209 ? 1.80600   17.74500 25.28700  1.000 39.20569  ? 209 LYS   L CB  1 
ATOM   3234 C  CG  . LYS   B 2 209 ? 0.67700   16.73600 25.41200  1.000 40.43596  ? 209 LYS   L CG  1 
ATOM   3235 C  CD  . LYS   B 2 209 ? 0.81000   15.91800 26.68600  1.000 36.58509  ? 209 LYS   L CD  1 
ATOM   3236 C  CE  . LYS   B 2 209 ? -0.23800  14.82100 26.74800  1.000 41.77304  ? 209 LYS   L CE  1 
ATOM   3237 N  NZ  . LYS   B 2 209 ? 0.08000   13.69900 25.82300  1.000 53.45519  ? 209 LYS   L NZ  1 
ATOM   3238 N  N   . SER   B 2 210 ? 4.05500   19.44800 27.07100  1.000 39.21470  ? 210 SER   L N   1 
ATOM   3239 C  CA  . SER   B 2 210 ? 5.19600   20.34700 27.13400  1.000 39.41522  ? 210 SER   L CA  1 
ATOM   3240 C  C   . SER   B 2 210 ? 6.45200   19.57700 27.51200  1.000 39.89044  ? 210 SER   L C   1 
ATOM   3241 O  O   . SER   B 2 210 ? 6.40100   18.41900 27.93400  1.000 37.58646  ? 210 SER   L O   1 
ATOM   3242 C  CB  . SER   B 2 210 ? 4.95300   21.48400 28.13200  1.000 43.73495  ? 210 SER   L CB  1 
ATOM   3243 O  OG  . SER   B 2 210 ? 5.22800   21.06500 29.45800  1.000 53.80402  ? 210 SER   L OG  1 
ATOM   3244 N  N   . PHE   B 2 211 ? 7.59100   20.24700 27.35000  1.000 44.15271  ? 211 PHE   L N   1 
ATOM   3245 C  CA  . PHE   B 2 211 ? 8.86700   19.73700 27.82300  1.000 41.85633  ? 211 PHE   L CA  1 
ATOM   3246 C  C   . PHE   B 2 211 ? 9.74600   20.91800 28.20600  1.000 50.16948  ? 211 PHE   L C   1 
ATOM   3247 O  O   . PHE   B 2 211 ? 9.55100   22.04100 27.73500  1.000 50.61128  ? 211 PHE   L O   1 
ATOM   3248 C  CB  . PHE   B 2 211 ? 9.56600   18.86500 26.76900  1.000 42.45553  ? 211 PHE   L CB  1 
ATOM   3249 C  CG  . PHE   B 2 211 ? 10.02600  19.62400 25.55000  1.000 48.08567  ? 211 PHE   L CG  1 
ATOM   3250 C  CD1 . PHE   B 2 211 ? 9.20900   19.73300 24.43700  1.000 44.96666  ? 211 PHE   L CD1 1 
ATOM   3251 C  CD2 . PHE   B 2 211 ? 11.28100  20.21600 25.51300  1.000 49.42465  ? 211 PHE   L CD2 1 
ATOM   3252 C  CE1 . PHE   B 2 211 ? 9.63000   20.42500 23.31600  1.000 46.24863  ? 211 PHE   L CE1 1 
ATOM   3253 C  CE2 . PHE   B 2 211 ? 11.70500  20.91100 24.39700  1.000 42.39701  ? 211 PHE   L CE2 1 
ATOM   3254 C  CZ  . PHE   B 2 211 ? 10.87900  21.01500 23.29700  1.000 46.96108  ? 211 PHE   L CZ  1 
ATOM   3255 N  N   . ASN   B 2 212 ? 10.71100  20.64900 29.07800  1.000 53.47949  ? 212 ASN   L N   1 
ATOM   3256 C  CA  . ASN   B 2 212 ? 11.77100  21.59300 29.39500  1.000 46.87850  ? 212 ASN   L CA  1 
ATOM   3257 C  C   . ASN   B 2 212 ? 13.02800  21.15600 28.65700  1.000 57.27161  ? 212 ASN   L C   1 
ATOM   3258 O  O   . ASN   B 2 212 ? 13.29500  19.95700 28.53100  1.000 66.52909  ? 212 ASN   L O   1 
ATOM   3259 C  CB  . ASN   B 2 212 ? 12.02200  21.65300 30.90400  1.000 52.10719  ? 212 ASN   L CB  1 
ATOM   3260 C  CG  . ASN   B 2 212 ? 10.91300  22.37700 31.64900  1.000 58.85457  ? 212 ASN   L CG  1 
ATOM   3261 O  OD1 . ASN   B 2 212 ? 9.73400   22.17400 31.36900  1.000 54.68335  ? 212 ASN   L OD1 1 
ATOM   3262 N  ND2 . ASN   B 2 212 ? 11.28500  23.20800 32.61200  1.000 61.35019  ? 212 ASN   L ND2 1 
ATOM   3263 N  N   . ARG   B 2 213 ? 13.79600  22.13100 28.16400  1.000 58.80362  ? 213 ARG   L N   1 
ATOM   3264 C  CA  . ARG   B 2 213 ? 14.93600  21.82500 27.30500  1.000 57.77779  ? 213 ARG   L CA  1 
ATOM   3265 C  C   . ARG   B 2 213 ? 15.96300  20.91400 27.97100  1.000 68.34377  ? 213 ARG   L C   1 
ATOM   3266 O  O   . ARG   B 2 213 ? 16.86300  20.41900 27.28300  1.000 70.15439  ? 213 ARG   L O   1 
ATOM   3267 C  CB  . ARG   B 2 213 ? 15.60600  23.12000 26.84800  1.000 50.93438  ? 213 ARG   L CB  1 
ATOM   3268 C  CG  . ARG   B 2 213 ? 16.25700  23.01300 25.48000  1.000 49.73702  ? 213 ARG   L CG  1 
ATOM   3269 C  CD  . ARG   B 2 213 ? 16.52800  24.38000 24.87900  1.000 58.34177  ? 213 ARG   L CD  1 
ATOM   3270 N  NE  . ARG   B 2 213 ? 16.74600  25.40100 25.89800  1.000 63.56445  ? 213 ARG   L NE  1 
ATOM   3271 C  CZ  . ARG   B 2 213 ? 17.91000  25.61700 26.50200  1.000 62.55026  ? 213 ARG   L CZ  1 
ATOM   3272 N  NH1 . ARG   B 2 213 ? 18.96700  24.87800 26.19300  1.000 55.24108  ? 213 ARG   L NH1 1 
ATOM   3273 N  NH2 . ARG   B 2 213 ? 18.01700  26.57100 27.41700  1.000 60.48107  ? 213 ARG   L NH2 1 
ATOM   3274 N  N   . GLY   B 2 214 ? 15.85500  20.68300 29.27600  1.000 72.74063  ? 214 GLY   L N   1 
ATOM   3275 C  CA  . GLY   B 2 214 ? 16.64900  19.67100 29.94300  1.000 75.34981  ? 214 GLY   L CA  1 
ATOM   3276 C  C   . GLY   B 2 214 ? 15.77100  18.58900 30.53700  1.000 78.55166  ? 214 GLY   L C   1 
ATOM   3277 O  O   . GLY   B 2 214 ? 15.14200  18.79500 31.57900  1.000 79.97947  ? 214 GLY   L O   1 
ATOM   3278 N  N   . GLU   B 2 215 ? 15.70900  17.43600 29.87800  1.000 82.59635  ? 215 GLU   L N   1 
ATOM   3279 C  CA  . GLU   B 2 215 ? 14.85600  16.34200 30.33200  1.000 93.89906  ? 215 GLU   L CA  1 
ATOM   3280 C  C   . GLU   B 2 215 ? 15.57100  14.99900 30.22500  1.000 97.81757  ? 215 GLU   L C   1 
ATOM   3281 O  O   . GLU   B 2 215 ? 15.60700  14.38600 29.15700  1.000 99.81322  ? 215 GLU   L O   1 
ATOM   3282 C  CB  . GLU   B 2 215 ? 13.55400  16.31000 29.52700  1.000 86.44771  ? 215 GLU   L CB  1 
HETATM 3283 C  C15 . A1H09 C 3 .   ? -15.57400 3.16000  -42.33200 0.000 54.47443  ? 301 A1H09 H C15 1 
HETATM 3284 O  O16 . A1H09 C 3 .   ? -16.81600 3.74700  -42.78800 0.000 54.48038  ? 301 A1H09 H O16 1 
HETATM 3285 C  C16 . A1H09 C 3 .   ? -17.31500 4.60900  -41.76300 0.000 54.92022  ? 301 A1H09 H C16 1 
HETATM 3286 O  O17 . A1H09 C 3 .   ? -18.21200 3.93300  -40.96400 0.000 54.47120  ? 301 A1H09 H O17 1 
HETATM 3287 C  C8  . A1H09 C 3 .   ? -16.08000 4.94800  -40.92300 0.000 55.52393  ? 301 A1H09 H C8  1 
HETATM 3288 O  O18 . A1H09 C 3 .   ? -15.21900 5.89200  -41.52400 0.000 55.85023  ? 301 A1H09 H O18 1 
HETATM 3289 C  C17 . A1H09 C 3 .   ? -15.44900 3.56500  -40.86800 0.000 54.91879  ? 301 A1H09 H C17 1 
HETATM 3290 O  O19 . A1H09 C 3 .   ? -14.09200 3.52100  -40.42400 0.000 54.95036  ? 301 A1H09 H O19 1 
HETATM 3291 C  C18 . A1H09 C 3 .   ? -15.53300 1.67400  -42.60400 0.000 54.23980  ? 301 A1H09 H C18 1 
HETATM 3292 O  O20 . A1H09 C 3 .   ? -14.32700 1.09900  -42.12000 0.000 54.16297  ? 301 A1H09 H O20 1 
HETATM 3293 O  O12 . A1H09 C 3 .   ? -15.80600 9.72200  -36.35200 1.000 53.47291  ? 301 A1H09 H O12 1 
HETATM 3294 C  C13 . A1H09 C 3 .   ? -16.59700 9.55500  -37.53700 1.000 57.37709  ? 301 A1H09 H C13 1 
HETATM 3295 O  O23 . A1H09 C 3 .   ? -16.63800 8.83800  -39.81300 1.000 65.14570  ? 301 A1H09 H O23 1 
HETATM 3296 C  C33 . A1H09 C 3 .   ? -15.33100 7.48800  -38.29900 1.000 60.26983  ? 301 A1H09 H C33 1 
HETATM 3297 O  O33 . A1H09 C 3 .   ? -15.88700 7.07600  -37.05300 1.000 58.35512  ? 301 A1H09 H O33 1 
HETATM 3298 C  C43 . A1H09 C 3 .   ? -13.80800 7.34000  -38.25700 1.000 62.49145  ? 301 A1H09 H C43 1 
HETATM 3299 O  O43 . A1H09 C 3 .   ? -13.19000 8.42400  -38.95500 1.000 53.62078  ? 301 A1H09 H O43 1 
HETATM 3300 C  C53 . A1H09 C 3 .   ? -13.33100 6.02300  -38.82800 1.000 56.37048  ? 301 A1H09 H C53 1 
HETATM 3301 C  C23 . A1H09 C 3 .   ? -15.81100 8.89800  -38.64900 1.000 61.67507  ? 301 A1H09 H C23 1 
HETATM 3302 O  O53 . A1H09 C 3 .   ? -14.21300 4.94700  -38.40100 1.000 54.56661  ? 301 A1H09 H O53 1 
HETATM 3303 P  P2  . A1H09 C 3 .   ? -13.98100 3.47300  -38.86900 0.000 54.82935  ? 301 A1H09 H P2  1 
HETATM 3304 O  O8  . A1H09 C 3 .   ? -12.50400 3.11900  -38.55300 0.000 54.46102  ? 301 A1H09 H O8  1 
HETATM 3305 O  O9  . A1H09 C 3 .   ? -14.91200 2.48700  -38.24000 0.000 54.56052  ? 301 A1H09 H O9  1 
HETATM 3306 C  C9  . A1H09 C 3 .   ? -14.50200 12.17700 -35.82800 1.000 51.80439  ? 301 A1H09 H C9  1 
HETATM 3307 O  O10 . A1H09 C 3 .   ? -15.92700 12.01700 -36.02100 1.000 56.40184  ? 301 A1H09 H O10 1 
HETATM 3308 C  C6  . A1H09 C 3 .   ? -16.27400 10.74200 -35.51500 1.000 50.15796  ? 301 A1H09 H C6  1 
HETATM 3309 C  C7  . A1H09 C 3 .   ? -15.46400 10.70100 -34.21800 1.000 45.01187  ? 301 A1H09 H C7  1 
HETATM 3310 O  O13 . A1H09 C 3 .   ? -15.98700 11.53200 -33.20300 1.000 43.51945  ? 301 A1H09 H O13 1 
HETATM 3311 C  C10 . A1H09 C 3 .   ? -14.11600 11.22100 -34.69800 1.000 45.22049  ? 301 A1H09 H C10 1 
HETATM 3312 O  O14 . A1H09 C 3 .   ? -13.39600 11.90700 -33.67400 1.000 40.55607  ? 301 A1H09 H O14 1 
HETATM 3313 C  C14 . A1H09 C 3 .   ? -13.75300 11.94100 -37.11900 1.000 56.27116  ? 301 A1H09 H C14 1 
HETATM 3314 O  O15 . A1H09 C 3 .   ? -12.34900 11.90900 -36.89700 1.000 54.81919  ? 301 A1H09 H O15 1 
HETATM 3315 O  O11 . A1H09 C 3 .   ? -15.41900 4.62400  -29.92800 1.000 43.19236  ? 301 A1H09 H O11 1 
HETATM 3316 C  C11 . A1H09 C 3 .   ? -15.19800 5.96000  -30.39800 1.000 38.90960  ? 301 A1H09 H C11 1 
HETATM 3317 O  O21 . A1H09 C 3 .   ? -14.70600 6.97000  -28.28700 1.000 39.46991  ? 301 A1H09 H O21 1 
HETATM 3318 C  C31 . A1H09 C 3 .   ? -13.56200 7.91500  -30.19700 1.000 37.48268  ? 301 A1H09 H C31 1 
HETATM 3319 O  O31 . A1H09 C 3 .   ? -12.52300 8.40200  -29.35300 1.000 31.42353  ? 301 A1H09 H O31 1 
HETATM 3320 C  C41 . A1H09 C 3 .   ? -14.54400 9.06200  -30.45500 1.000 37.63892  ? 301 A1H09 H C41 1 
HETATM 3321 O  O41 . A1H09 C 3 .   ? -15.51700 8.68000  -31.42900 1.000 36.31437  ? 301 A1H09 H O41 1 
HETATM 3322 C  C51 . A1H09 C 3 .   ? -13.84100 10.29400 -30.97200 1.000 35.77178  ? 301 A1H09 H C51 1 
HETATM 3323 C  C21 . A1H09 C 3 .   ? -14.14100 6.64700  -29.56000 1.000 39.64084  ? 301 A1H09 H C21 1 
HETATM 3324 O  O51 . A1H09 C 3 .   ? -13.15100 9.92800  -32.19800 1.000 38.09747  ? 301 A1H09 H O51 1 
HETATM 3325 P  P1  . A1H09 C 3 .   ? -12.33300 10.98000 -33.01400 1.000 40.39295  ? 301 A1H09 H P1  1 
HETATM 3326 O  O6  . A1H09 C 3 .   ? -11.59700 11.86700 -31.97800 1.000 39.84323  ? 301 A1H09 H O6  1 
HETATM 3327 O  O7  . A1H09 C 3 .   ? -11.37200 10.39000 -33.99200 1.000 41.99131  ? 301 A1H09 H O7  1 
HETATM 3328 C  C42 . A1H09 C 3 .   ? -15.71700 2.25900  -31.81200 1.000 54.51209  ? 301 A1H09 H C42 1 
HETATM 3329 O  O42 . A1H09 C 3 .   ? -14.77700 3.36000  -31.77700 1.000 56.56956  ? 301 A1H09 H O42 1 
HETATM 3330 C  C12 . A1H09 C 3 .   ? -14.50100 3.68500  -30.41200 1.000 50.59414  ? 301 A1H09 H C12 1 
HETATM 3331 C  C22 . A1H09 C 3 .   ? -14.76600 2.36600  -29.68300 1.000 52.99718  ? 301 A1H09 H C22 1 
HETATM 3332 O  O22 . A1H09 C 3 .   ? -13.77200 1.38600  -29.89500 1.000 54.89992  ? 301 A1H09 H O22 1 
HETATM 3333 C  C32 . A1H09 C 3 .   ? -16.07000 1.97100  -30.35700 1.000 53.85460  ? 301 A1H09 H C32 1 
HETATM 3334 O  O32 . A1H09 C 3 .   ? -16.43800 0.60200  -30.18300 1.000 67.84868  ? 301 A1H09 H O32 1 
HETATM 3335 C  C52 . A1H09 C 3 .   ? -16.88900 2.55700  -32.71900 1.000 61.97427  ? 301 A1H09 H C52 1 
HETATM 3336 O  O52 . A1H09 C 3 .   ? -17.65500 3.65100  -32.23300 1.000 64.56361  ? 301 A1H09 H O52 1 
HETATM 3337 O  O1  . A1H09 C 3 .   ? -11.66900 -1.14600 -27.86600 0.800 40.70971  ? 301 A1H09 H O1  1 
HETATM 3338 C  C1  . A1H09 C 3 .   ? -11.72000 -1.54000 -26.49700 0.800 50.05608  ? 301 A1H09 H C1  1 
HETATM 3339 O  O2  . A1H09 C 3 .   ? -12.58300 -0.97200 -24.31800 0.900 49.87150  ? 301 A1H09 H O2  1 
HETATM 3340 C  C3  . A1H09 C 3 .   ? -14.13700 -0.88200 -26.18200 0.800 58.07815  ? 301 A1H09 H C3  1 
HETATM 3341 O  O3  . A1H09 C 3 .   ? -14.17500 -0.73600 -27.59800 0.800 55.87583  ? 301 A1H09 H O3  1 
HETATM 3342 C  C4  . A1H09 C 3 .   ? -15.13200 0.09800  -25.55600 0.800 55.98153  ? 301 A1H09 H C4  1 
HETATM 3343 O  O4  . A1H09 C 3 .   ? -15.40000 -0.27800 -24.20400 0.800 62.85586  ? 301 A1H09 H O4  1 
HETATM 3344 C  C5  . A1H09 C 3 .   ? -16.42800 0.16000  -26.32900 0.800 56.79043  ? 301 A1H09 H C5  1 
HETATM 3345 C  C2  . A1H09 C 3 .   ? -12.69300 -0.68500 -25.71400 0.800 51.34561  ? 301 A1H09 H C2  1 
HETATM 3346 O  O5  . A1H09 C 3 .   ? -16.10400 0.43700  -27.71900 0.800 59.58883  ? 301 A1H09 H O5  1 
HETATM 3347 P  P   . A1H09 C 3 .   ? -17.18000 0.30100  -28.84400 1.000 79.78163  ? 301 A1H09 H P   1 
HETATM 3348 O  O2P . A1H09 C 3 .   ? -17.54800 -1.20500 -28.89100 1.000 66.74639  ? 301 A1H09 H O2P 1 
HETATM 3349 O  O1P . A1H09 C 3 .   ? -18.39900 1.14000  -28.63400 1.000 68.54514  ? 301 A1H09 H O1P 1 
HETATM 3350 ZN ZN  . ZN    D 4 .   ? -11.96400 26.92900 -12.71200 1.000 107.65706 ? 301 ZN    L ZN  1 
HETATM 3351 O  O   . HOH   E 5 .   ? 9.12100   15.77300 -9.12000  1.000 35.99952  ? 401 HOH   H O   1 
HETATM 3352 O  O   . HOH   E 5 .   ? -5.84400  23.03800 -11.92000 1.000 29.21862  ? 402 HOH   H O   1 
HETATM 3353 O  O   . HOH   E 5 .   ? 7.88100   15.73000 -29.93800 1.000 30.96386  ? 403 HOH   H O   1 
HETATM 3354 O  O   . HOH   E 5 .   ? 10.27900  14.92100 -20.53500 1.000 31.74278  ? 404 HOH   H O   1 
HETATM 3355 O  O   . HOH   E 5 .   ? -12.67400 6.32900  -14.02200 1.000 35.00314  ? 405 HOH   H O   1 
HETATM 3356 O  O   . HOH   E 5 .   ? -12.32500 12.87900 -25.25100 1.000 30.50024  ? 406 HOH   H O   1 
HETATM 3357 O  O   . HOH   E 5 .   ? 8.17400   17.72400 -10.61600 1.000 32.89560  ? 407 HOH   H O   1 
HETATM 3358 O  O   . HOH   E 5 .   ? 9.10300   10.45400 -21.44600 1.000 34.82389  ? 408 HOH   H O   1 
HETATM 3359 O  O   . HOH   E 5 .   ? 1.19400   11.70200 -10.24100 1.000 28.73381  ? 409 HOH   H O   1 
HETATM 3360 O  O   . HOH   E 5 .   ? -0.94200  25.18000 -29.89500 1.000 37.07410  ? 410 HOH   H O   1 
HETATM 3361 O  O   . HOH   E 5 .   ? 6.57700   31.52800 -14.88400 1.000 38.88109  ? 411 HOH   H O   1 
HETATM 3362 O  O   . HOH   E 5 .   ? 4.08700   25.52100 -30.00200 1.000 29.83542  ? 412 HOH   H O   1 
HETATM 3363 O  O   . HOH   E 5 .   ? 7.08600   13.70000 -12.31700 1.000 34.29767  ? 413 HOH   H O   1 
HETATM 3364 O  O   . HOH   E 5 .   ? -20.53400 6.31600  -24.37500 1.000 41.53499  ? 414 HOH   H O   1 
HETATM 3365 O  O   . HOH   E 5 .   ? -8.39200  5.11800  -14.40600 1.000 26.51673  ? 415 HOH   H O   1 
HETATM 3366 O  O   . HOH   E 5 .   ? 16.23900  8.83700  17.54900  1.000 38.87454  ? 416 HOH   H O   1 
HETATM 3367 O  O   . HOH   E 5 .   ? 13.00100  27.93400 -2.92900  1.000 26.04356  ? 417 HOH   H O   1 
HETATM 3368 O  O   . HOH   E 5 .   ? -1.73600  21.58300 -2.70600  1.000 28.03145  ? 418 HOH   H O   1 
HETATM 3369 O  O   . HOH   E 5 .   ? -4.78300  3.04100  -16.35600 1.000 30.06074  ? 419 HOH   H O   1 
HETATM 3370 O  O   . HOH   E 5 .   ? -7.27300  20.69300 -36.57300 1.000 24.47868  ? 420 HOH   H O   1 
HETATM 3371 O  O   . HOH   E 5 .   ? 18.93800  3.46200  3.11900   1.000 50.54865  ? 421 HOH   H O   1 
HETATM 3372 O  O   . HOH   E 5 .   ? 7.08700   29.75500 -0.92200  1.000 41.79143  ? 422 HOH   H O   1 
HETATM 3373 O  O   . HOH   E 5 .   ? 16.14900  19.80800 -12.92500 1.000 51.52692  ? 423 HOH   H O   1 
HETATM 3374 O  O   . HOH   E 5 .   ? 9.29200   0.00000  0.00000   0.500 47.85523  ? 424 HOH   H O   1 
HETATM 3375 O  O   . HOH   E 5 .   ? 0.95400   19.96000 -34.98400 1.000 30.38404  ? 425 HOH   H O   1 
HETATM 3376 O  O   . HOH   F 5 .   ? -21.91700 22.55400 -28.81800 1.000 42.94144  ? 401 HOH   L O   1 
HETATM 3377 O  O   . HOH   F 5 .   ? -25.09900 -0.88200 -11.55700 1.000 49.17672  ? 402 HOH   L O   1 
HETATM 3378 O  O   . HOH   F 5 .   ? -13.27800 7.98800  4.45300   1.000 47.18372  ? 403 HOH   L O   1 
HETATM 3379 O  O   . HOH   F 5 .   ? 3.37300   20.22200 9.96700   1.000 39.07324  ? 404 HOH   L O   1 
HETATM 3380 O  O   . HOH   F 5 .   ? -21.63400 2.78100  -18.59600 1.000 40.37262  ? 405 HOH   L O   1 
HETATM 3381 O  O   . HOH   F 5 .   ? -28.07800 4.43700  -10.84500 1.000 40.94898  ? 406 HOH   L O   1 
HETATM 3382 O  O   . HOH   F 5 .   ? -23.32000 28.89800 -12.63300 1.000 31.70086  ? 407 HOH   L O   1 
HETATM 3383 O  O   . HOH   F 5 .   ? -7.84900  6.36600  4.97500   1.000 47.83046  ? 408 HOH   L O   1 
HETATM 3384 O  O   . HOH   F 5 .   ? -20.34100 14.34400 14.69600  1.000 35.78562  ? 409 HOH   L O   1 
HETATM 3385 O  O   . HOH   F 5 .   ? -16.87700 5.65600  -3.59200  1.000 45.84996  ? 410 HOH   L O   1 
HETATM 3386 O  O   . HOH   F 5 .   ? -26.25100 14.84600 -13.58700 1.000 35.14068  ? 411 HOH   L O   1 
HETATM 3387 O  O   . HOH   F 5 .   ? 9.95400   23.07900 10.26700  1.000 32.93385  ? 412 HOH   L O   1 
HETATM 3388 O  O   . HOH   F 5 .   ? -10.11900 8.56200  -7.21800  1.000 31.91096  ? 413 HOH   L O   1 
HETATM 3389 O  O   . HOH   F 5 .   ? -4.78400  26.27100 15.30200  1.000 37.30694  ? 414 HOH   L O   1 
HETATM 3390 O  O   . HOH   F 5 .   ? -21.71700 26.17200 -0.65200  1.000 34.89225  ? 415 HOH   L O   1 
HETATM 3391 O  O   . HOH   F 5 .   ? -22.52300 8.99100  -24.18900 1.000 54.86735  ? 416 HOH   L O   1 
HETATM 3392 O  O   . HOH   F 5 .   ? -12.49500 24.05200 -16.60000 1.000 35.99910  ? 417 HOH   L O   1 
HETATM 3393 O  O   . HOH   F 5 .   ? -30.01700 13.21100 3.69600   1.000 43.33534  ? 418 HOH   L O   1 
HETATM 3394 O  O   . HOH   F 5 .   ? -3.30200  13.13700 25.16400  1.000 36.20379  ? 419 HOH   L O   1 
HETATM 3395 O  O   . HOH   F 5 .   ? 16.90000  22.57600 9.55100   1.000 42.95837  ? 420 HOH   L O   1 
HETATM 3396 O  O   . HOH   F 5 .   ? 6.15800   19.38400 8.85500   1.000 35.48640  ? 421 HOH   L O   1 
HETATM 3397 O  O   . HOH   F 5 .   ? -2.74700  19.54800 5.04000   1.000 27.54891  ? 422 HOH   L O   1 
HETATM 3398 O  O   . HOH   F 5 .   ? -5.69900  14.45200 -5.30800  1.000 39.66519  ? 423 HOH   L O   1 
HETATM 3399 O  O   . HOH   F 5 .   ? -14.70600 22.25400 -2.81000  1.000 44.65909  ? 424 HOH   L O   1 
HETATM 3400 O  O   . HOH   F 5 .   ? -4.51200  6.89700  -9.73400  1.000 35.58254  ? 425 HOH   L O   1 
HETATM 3401 O  O   . HOH   F 5 .   ? -31.25600 7.48600  3.07700   1.000 37.17223  ? 426 HOH   L O   1 
HETATM 3402 O  O   . HOH   F 5 .   ? -16.32000 17.45200 26.82000  1.000 50.00963  ? 427 HOH   L O   1 
HETATM 3403 O  O   . HOH   F 5 .   ? 3.73000   18.04100 7.59900   1.000 40.31854  ? 428 HOH   L O   1 
HETATM 3404 O  O   . HOH   F 5 .   ? -16.48700 4.63700  11.85400  1.000 35.28072  ? 429 HOH   L O   1 
# 
