data_8YRG
# 
_entry.id   8YRG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.392 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8YRG         pdb_00008yrg 10.2210/pdb8yrg/pdb 
WWPDB D_1300040621 ?            ?                   
EMDB  EMD-39542    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-05-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8YRG 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'CryoEM structure of fospropofol-bound MRGPRX4-Gq complex' 
_pdbx_database_related.db_id          EMD-39542 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              bryan_roth@med.unc.edu 
_pdbx_contact_author.name_first         Bryan 
_pdbx_contact_author.name_last          Roth 
_pdbx_contact_author.name_mi            L 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0561-6520 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Cao, C.'    1 0000-0003-4017-741X 
'Fay, J.F.'  2 0000-0003-1822-2384 
'Roth, B.L.' 3 0000-0002-0561-6520 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Sci Transl Med' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1946-6242 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                eadk8198 
_citation.page_last                 eadk8198 
_citation.title                     'MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/scitranslmed.adk8198 
_citation.pdbx_database_id_PubMed   38718132 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chien, D.C.'      1 0000-0001-6844-5477 
primary 'Limjunyawong, N.' 2 0000-0002-9540-6171 
primary 'Cao, C.'          3 0000-0003-4017-741X 
primary 'Meixiong, J.'     4 0000-0001-6776-3975 
primary 'Peng, Q.'         5 ?                   
primary 'Ho, C.Y.'         6 0000-0003-1036-8370 
primary 'Fay, J.F.'        7 0000-0003-1822-2384 
primary 'Roth, B.L.'       8 0000-0002-0561-6520 
primary 'Dong, X.'         9 0000-0002-9750-7718 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Gs-mini-Gq chimera'                                                       28084.832 1 ? ? ? ? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'         39418.086 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'        7861.143  1 ? ? ? ? 
4 polymer     man scFv16                                                                     28668.922 1 ? ? ? ? 
5 polymer     man 'Soluble cytochrome b562,Mas-related G-protein coupled receptor member X4' 53396.020 1 ? ? ? ? 
6 non-polymer syn '[2,6-di(propan-2-yl)phenoxy]methyl dihydrogen phosphate'                  288.277   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 'Transducin beta chain 1'                                                 
3 'G gamma-I'                                                               
5 'Cytochrome b-562,Sensory neuron-specific G-protein coupled receptor 5/6' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGSTVSAEDKAAAERSKMIDKNLREDGEKARRTLRLLLLGADNSGKSTIVKQMRILHGGSGGSGGTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI
EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASGDGRHICYPHFTCAVDTENARRIFNDCKDIILQMNL
REYNLV
;
;MGSTVSAEDKAAAERSKMIDKNLREDGEKARRTLRLLLLGADNSGKSTIVKQMRILHGGSGGSGGTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI
EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASGDGRHICYPHFTCAVDTENARRIFNDCKDIILQMNL
REYNLV
;
B ? 
2 'polypeptide(L)' no no 
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
C ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL D ? 
4 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
E ? 
5 'polypeptide(L)' no no 
;DYKDDDDAKLQTMHHHHHHHHHHENLYFQGGTTMADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPP
KLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLGSTLEVLFQGPDPTVPVFGT
KLTPINGREETPCYNQTLSFTVLTCIISLVGLTGNAVVLWLLGYRMRRNAVSIYILNLAAADFLFLSFQIIRSPLRLINI
SHLIRKILVSVMTFPYFTGLSMLSAISTERCLSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLFSMLEWRFCDFLFSGADS
SWCETSDFIPVAWLIFLCVVLCVSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGILGALIYRMHLNLEVLY
CHVYLVCMSLSSLNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDKPEVDKGEGQLPEESLELSGSRLGP
;
;DYKDDDDAKLQTMHHHHHHHHHHENLYFQGGTTMADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPP
KLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLGSTLEVLFQGPDPTVPVFGT
KLTPINGREETPCYNQTLSFTVLTCIISLVGLTGNAVVLWLLGYRMRRNAVSIYILNLAAADFLFLSFQIIRSPLRLINI
SHLIRKILVSVMTFPYFTGLSMLSAISTERCLSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLFSMLEWRFCDFLFSGADS
SWCETSDFIPVAWLIFLCVVLCVSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGILGALIYRMHLNLEVLY
CHVYLVCMSLSSLNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDKPEVDKGEGQLPEESLELSGSRLGP
;
R ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        '[2,6-di(propan-2-yl)phenoxy]methyl dihydrogen phosphate' 
_pdbx_entity_nonpoly.comp_id     A1LZU 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   THR n 
1 5   VAL n 
1 6   SER n 
1 7   ALA n 
1 8   GLU n 
1 9   ASP n 
1 10  LYS n 
1 11  ALA n 
1 12  ALA n 
1 13  ALA n 
1 14  GLU n 
1 15  ARG n 
1 16  SER n 
1 17  LYS n 
1 18  MET n 
1 19  ILE n 
1 20  ASP n 
1 21  LYS n 
1 22  ASN n 
1 23  LEU n 
1 24  ARG n 
1 25  GLU n 
1 26  ASP n 
1 27  GLY n 
1 28  GLU n 
1 29  LYS n 
1 30  ALA n 
1 31  ARG n 
1 32  ARG n 
1 33  THR n 
1 34  LEU n 
1 35  ARG n 
1 36  LEU n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLY n 
1 41  ALA n 
1 42  ASP n 
1 43  ASN n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  SER n 
1 48  THR n 
1 49  ILE n 
1 50  VAL n 
1 51  LYS n 
1 52  GLN n 
1 53  MET n 
1 54  ARG n 
1 55  ILE n 
1 56  LEU n 
1 57  HIS n 
1 58  GLY n 
1 59  GLY n 
1 60  SER n 
1 61  GLY n 
1 62  GLY n 
1 63  SER n 
1 64  GLY n 
1 65  GLY n 
1 66  THR n 
1 67  SER n 
1 68  GLY n 
1 69  ILE n 
1 70  PHE n 
1 71  GLU n 
1 72  THR n 
1 73  LYS n 
1 74  PHE n 
1 75  GLN n 
1 76  VAL n 
1 77  ASP n 
1 78  LYS n 
1 79  VAL n 
1 80  ASN n 
1 81  PHE n 
1 82  HIS n 
1 83  MET n 
1 84  PHE n 
1 85  ASP n 
1 86  VAL n 
1 87  GLY n 
1 88  GLY n 
1 89  GLN n 
1 90  ARG n 
1 91  ASP n 
1 92  GLU n 
1 93  ARG n 
1 94  ARG n 
1 95  LYS n 
1 96  TRP n 
1 97  ILE n 
1 98  GLN n 
1 99  CYS n 
1 100 PHE n 
1 101 ASN n 
1 102 ASP n 
1 103 VAL n 
1 104 THR n 
1 105 ALA n 
1 106 ILE n 
1 107 ILE n 
1 108 PHE n 
1 109 VAL n 
1 110 VAL n 
1 111 ASP n 
1 112 SER n 
1 113 SER n 
1 114 ASP n 
1 115 TYR n 
1 116 ASN n 
1 117 ARG n 
1 118 LEU n 
1 119 GLN n 
1 120 GLU n 
1 121 ALA n 
1 122 LEU n 
1 123 ASN n 
1 124 ASP n 
1 125 PHE n 
1 126 LYS n 
1 127 SER n 
1 128 ILE n 
1 129 TRP n 
1 130 ASN n 
1 131 ASN n 
1 132 ARG n 
1 133 TRP n 
1 134 LEU n 
1 135 ARG n 
1 136 THR n 
1 137 ILE n 
1 138 SER n 
1 139 VAL n 
1 140 ILE n 
1 141 LEU n 
1 142 PHE n 
1 143 LEU n 
1 144 ASN n 
1 145 LYS n 
1 146 GLN n 
1 147 ASP n 
1 148 LEU n 
1 149 LEU n 
1 150 ALA n 
1 151 GLU n 
1 152 LYS n 
1 153 VAL n 
1 154 LEU n 
1 155 ALA n 
1 156 GLY n 
1 157 LYS n 
1 158 SER n 
1 159 LYS n 
1 160 ILE n 
1 161 GLU n 
1 162 ASP n 
1 163 TYR n 
1 164 PHE n 
1 165 PRO n 
1 166 GLU n 
1 167 PHE n 
1 168 ALA n 
1 169 ARG n 
1 170 TYR n 
1 171 THR n 
1 172 THR n 
1 173 PRO n 
1 174 GLU n 
1 175 ASP n 
1 176 ALA n 
1 177 THR n 
1 178 PRO n 
1 179 GLU n 
1 180 PRO n 
1 181 GLY n 
1 182 GLU n 
1 183 ASP n 
1 184 PRO n 
1 185 ARG n 
1 186 VAL n 
1 187 THR n 
1 188 ARG n 
1 189 ALA n 
1 190 LYS n 
1 191 TYR n 
1 192 PHE n 
1 193 ILE n 
1 194 ARG n 
1 195 LYS n 
1 196 GLU n 
1 197 PHE n 
1 198 VAL n 
1 199 ASP n 
1 200 ILE n 
1 201 SER n 
1 202 THR n 
1 203 ALA n 
1 204 SER n 
1 205 GLY n 
1 206 ASP n 
1 207 GLY n 
1 208 ARG n 
1 209 HIS n 
1 210 ILE n 
1 211 CYS n 
1 212 TYR n 
1 213 PRO n 
1 214 HIS n 
1 215 PHE n 
1 216 THR n 
1 217 CYS n 
1 218 ALA n 
1 219 VAL n 
1 220 ASP n 
1 221 THR n 
1 222 GLU n 
1 223 ASN n 
1 224 ALA n 
1 225 ARG n 
1 226 ARG n 
1 227 ILE n 
1 228 PHE n 
1 229 ASN n 
1 230 ASP n 
1 231 CYS n 
1 232 LYS n 
1 233 ASP n 
1 234 ILE n 
1 235 ILE n 
1 236 LEU n 
1 237 GLN n 
1 238 MET n 
1 239 ASN n 
1 240 LEU n 
1 241 ARG n 
1 242 GLU n 
1 243 TYR n 
1 244 ASN n 
1 245 LEU n 
1 246 VAL n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   LEU n 
2 9   GLU n 
2 10  VAL n 
2 11  LEU n 
2 12  PHE n 
2 13  GLN n 
2 14  GLY n 
2 15  PRO n 
2 16  GLY n 
2 17  SER n 
2 18  SER n 
2 19  GLY n 
2 20  SER n 
2 21  GLU n 
2 22  LEU n 
2 23  ASP n 
2 24  GLN n 
2 25  LEU n 
2 26  ARG n 
2 27  GLN n 
2 28  GLU n 
2 29  ALA n 
2 30  GLU n 
2 31  GLN n 
2 32  LEU n 
2 33  LYS n 
2 34  ASN n 
2 35  GLN n 
2 36  ILE n 
2 37  ARG n 
2 38  ASP n 
2 39  ALA n 
2 40  ARG n 
2 41  LYS n 
2 42  ALA n 
2 43  CYS n 
2 44  ALA n 
2 45  ASP n 
2 46  ALA n 
2 47  THR n 
2 48  LEU n 
2 49  SER n 
2 50  GLN n 
2 51  ILE n 
2 52  THR n 
2 53  ASN n 
2 54  ASN n 
2 55  ILE n 
2 56  ASP n 
2 57  PRO n 
2 58  VAL n 
2 59  GLY n 
2 60  ARG n 
2 61  ILE n 
2 62  GLN n 
2 63  MET n 
2 64  ARG n 
2 65  THR n 
2 66  ARG n 
2 67  ARG n 
2 68  THR n 
2 69  LEU n 
2 70  ARG n 
2 71  GLY n 
2 72  HIS n 
2 73  LEU n 
2 74  ALA n 
2 75  LYS n 
2 76  ILE n 
2 77  TYR n 
2 78  ALA n 
2 79  MET n 
2 80  HIS n 
2 81  TRP n 
2 82  GLY n 
2 83  THR n 
2 84  ASP n 
2 85  SER n 
2 86  ARG n 
2 87  LEU n 
2 88  LEU n 
2 89  VAL n 
2 90  SER n 
2 91  ALA n 
2 92  SER n 
2 93  GLN n 
2 94  ASP n 
2 95  GLY n 
2 96  LYS n 
2 97  LEU n 
2 98  ILE n 
2 99  ILE n 
2 100 TRP n 
2 101 ASP n 
2 102 SER n 
2 103 TYR n 
2 104 THR n 
2 105 THR n 
2 106 ASN n 
2 107 LYS n 
2 108 VAL n 
2 109 HIS n 
2 110 ALA n 
2 111 ILE n 
2 112 PRO n 
2 113 LEU n 
2 114 ARG n 
2 115 SER n 
2 116 SER n 
2 117 TRP n 
2 118 VAL n 
2 119 MET n 
2 120 THR n 
2 121 CYS n 
2 122 ALA n 
2 123 TYR n 
2 124 ALA n 
2 125 PRO n 
2 126 SER n 
2 127 GLY n 
2 128 ASN n 
2 129 TYR n 
2 130 VAL n 
2 131 ALA n 
2 132 CYS n 
2 133 GLY n 
2 134 GLY n 
2 135 LEU n 
2 136 ASP n 
2 137 ASN n 
2 138 ILE n 
2 139 CYS n 
2 140 SER n 
2 141 ILE n 
2 142 TYR n 
2 143 ASN n 
2 144 LEU n 
2 145 LYS n 
2 146 THR n 
2 147 ARG n 
2 148 GLU n 
2 149 GLY n 
2 150 ASN n 
2 151 VAL n 
2 152 ARG n 
2 153 VAL n 
2 154 SER n 
2 155 ARG n 
2 156 GLU n 
2 157 LEU n 
2 158 ALA n 
2 159 GLY n 
2 160 HIS n 
2 161 THR n 
2 162 GLY n 
2 163 TYR n 
2 164 LEU n 
2 165 SER n 
2 166 CYS n 
2 167 CYS n 
2 168 ARG n 
2 169 PHE n 
2 170 LEU n 
2 171 ASP n 
2 172 ASP n 
2 173 ASN n 
2 174 GLN n 
2 175 ILE n 
2 176 VAL n 
2 177 THR n 
2 178 SER n 
2 179 SER n 
2 180 GLY n 
2 181 ASP n 
2 182 THR n 
2 183 THR n 
2 184 CYS n 
2 185 ALA n 
2 186 LEU n 
2 187 TRP n 
2 188 ASP n 
2 189 ILE n 
2 190 GLU n 
2 191 THR n 
2 192 GLY n 
2 193 GLN n 
2 194 GLN n 
2 195 THR n 
2 196 THR n 
2 197 THR n 
2 198 PHE n 
2 199 THR n 
2 200 GLY n 
2 201 HIS n 
2 202 THR n 
2 203 GLY n 
2 204 ASP n 
2 205 VAL n 
2 206 MET n 
2 207 SER n 
2 208 LEU n 
2 209 SER n 
2 210 LEU n 
2 211 ALA n 
2 212 PRO n 
2 213 ASP n 
2 214 THR n 
2 215 ARG n 
2 216 LEU n 
2 217 PHE n 
2 218 VAL n 
2 219 SER n 
2 220 GLY n 
2 221 ALA n 
2 222 CYS n 
2 223 ASP n 
2 224 ALA n 
2 225 SER n 
2 226 ALA n 
2 227 LYS n 
2 228 LEU n 
2 229 TRP n 
2 230 ASP n 
2 231 VAL n 
2 232 ARG n 
2 233 GLU n 
2 234 GLY n 
2 235 MET n 
2 236 CYS n 
2 237 ARG n 
2 238 GLN n 
2 239 THR n 
2 240 PHE n 
2 241 THR n 
2 242 GLY n 
2 243 HIS n 
2 244 GLU n 
2 245 SER n 
2 246 ASP n 
2 247 ILE n 
2 248 ASN n 
2 249 ALA n 
2 250 ILE n 
2 251 CYS n 
2 252 PHE n 
2 253 PHE n 
2 254 PRO n 
2 255 ASN n 
2 256 GLY n 
2 257 ASN n 
2 258 ALA n 
2 259 PHE n 
2 260 ALA n 
2 261 THR n 
2 262 GLY n 
2 263 SER n 
2 264 ASP n 
2 265 ASP n 
2 266 ALA n 
2 267 THR n 
2 268 CYS n 
2 269 ARG n 
2 270 LEU n 
2 271 PHE n 
2 272 ASP n 
2 273 LEU n 
2 274 ARG n 
2 275 ALA n 
2 276 ASP n 
2 277 GLN n 
2 278 GLU n 
2 279 LEU n 
2 280 MET n 
2 281 THR n 
2 282 TYR n 
2 283 SER n 
2 284 HIS n 
2 285 ASP n 
2 286 ASN n 
2 287 ILE n 
2 288 ILE n 
2 289 CYS n 
2 290 GLY n 
2 291 ILE n 
2 292 THR n 
2 293 SER n 
2 294 VAL n 
2 295 SER n 
2 296 PHE n 
2 297 SER n 
2 298 LYS n 
2 299 SER n 
2 300 GLY n 
2 301 ARG n 
2 302 LEU n 
2 303 LEU n 
2 304 LEU n 
2 305 ALA n 
2 306 GLY n 
2 307 TYR n 
2 308 ASP n 
2 309 ASP n 
2 310 PHE n 
2 311 ASN n 
2 312 CYS n 
2 313 ASN n 
2 314 VAL n 
2 315 TRP n 
2 316 ASP n 
2 317 ALA n 
2 318 LEU n 
2 319 LYS n 
2 320 ALA n 
2 321 ASP n 
2 322 ARG n 
2 323 ALA n 
2 324 GLY n 
2 325 VAL n 
2 326 LEU n 
2 327 ALA n 
2 328 GLY n 
2 329 HIS n 
2 330 ASP n 
2 331 ASN n 
2 332 ARG n 
2 333 VAL n 
2 334 SER n 
2 335 CYS n 
2 336 LEU n 
2 337 GLY n 
2 338 VAL n 
2 339 THR n 
2 340 ASP n 
2 341 ASP n 
2 342 GLY n 
2 343 MET n 
2 344 ALA n 
2 345 VAL n 
2 346 ALA n 
2 347 THR n 
2 348 GLY n 
2 349 SER n 
2 350 TRP n 
2 351 ASP n 
2 352 SER n 
2 353 PHE n 
2 354 LEU n 
2 355 LYS n 
2 356 ILE n 
2 357 TRP n 
2 358 ASN n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   ASP n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  ARG n 
4 19  LYS n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  SER n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  ALA n 
4 29  PHE n 
4 30  SER n 
4 31  SER n 
4 32  PHE n 
4 33  GLY n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLU n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  VAL n 
4 49  ALA n 
4 50  TYR n 
4 51  ILE n 
4 52  SER n 
4 53  SER n 
4 54  GLY n 
4 55  SER n 
4 56  GLY n 
4 57  THR n 
4 58  ILE n 
4 59  TYR n 
4 60  TYR n 
4 61  ALA n 
4 62  ASP n 
4 63  THR n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  ILE n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASP n 
4 75  PRO n 
4 76  LYS n 
4 77  ASN n 
4 78  THR n 
4 79  LEU n 
4 80  PHE n 
4 81  LEU n 
4 82  GLN n 
4 83  MET n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  ARG n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  MET n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  VAL n 
4 98  ARG n 
4 99  SER n 
4 100 ILE n 
4 101 TYR n 
4 102 TYR n 
4 103 TYR n 
4 104 GLY n 
4 105 SER n 
4 106 SER n 
4 107 PRO n 
4 108 PHE n 
4 109 ASP n 
4 110 PHE n 
4 111 TRP n 
4 112 GLY n 
4 113 GLN n 
4 114 GLY n 
4 115 THR n 
4 116 THR n 
4 117 LEU n 
4 118 THR n 
4 119 VAL n 
4 120 SER n 
4 121 SER n 
4 122 GLY n 
4 123 GLY n 
4 124 GLY n 
4 125 GLY n 
4 126 SER n 
4 127 GLY n 
4 128 GLY n 
4 129 GLY n 
4 130 GLY n 
4 131 SER n 
4 132 GLY n 
4 133 GLY n 
4 134 GLY n 
4 135 GLY n 
4 136 SER n 
4 137 ASP n 
4 138 ILE n 
4 139 VAL n 
4 140 MET n 
4 141 THR n 
4 142 GLN n 
4 143 ALA n 
4 144 THR n 
4 145 SER n 
4 146 SER n 
4 147 VAL n 
4 148 PRO n 
4 149 VAL n 
4 150 THR n 
4 151 PRO n 
4 152 GLY n 
4 153 GLU n 
4 154 SER n 
4 155 VAL n 
4 156 SER n 
4 157 ILE n 
4 158 SER n 
4 159 CYS n 
4 160 ARG n 
4 161 SER n 
4 162 SER n 
4 163 LYS n 
4 164 SER n 
4 165 LEU n 
4 166 LEU n 
4 167 HIS n 
4 168 SER n 
4 169 ASN n 
4 170 GLY n 
4 171 ASN n 
4 172 THR n 
4 173 TYR n 
4 174 LEU n 
4 175 TYR n 
4 176 TRP n 
4 177 PHE n 
4 178 LEU n 
4 179 GLN n 
4 180 ARG n 
4 181 PRO n 
4 182 GLY n 
4 183 GLN n 
4 184 SER n 
4 185 PRO n 
4 186 GLN n 
4 187 LEU n 
4 188 LEU n 
4 189 ILE n 
4 190 TYR n 
4 191 ARG n 
4 192 MET n 
4 193 SER n 
4 194 ASN n 
4 195 LEU n 
4 196 ALA n 
4 197 SER n 
4 198 GLY n 
4 199 VAL n 
4 200 PRO n 
4 201 ASP n 
4 202 ARG n 
4 203 PHE n 
4 204 SER n 
4 205 GLY n 
4 206 SER n 
4 207 GLY n 
4 208 SER n 
4 209 GLY n 
4 210 THR n 
4 211 ALA n 
4 212 PHE n 
4 213 THR n 
4 214 LEU n 
4 215 THR n 
4 216 ILE n 
4 217 SER n 
4 218 ARG n 
4 219 LEU n 
4 220 GLU n 
4 221 ALA n 
4 222 GLU n 
4 223 ASP n 
4 224 VAL n 
4 225 GLY n 
4 226 VAL n 
4 227 TYR n 
4 228 TYR n 
4 229 CYS n 
4 230 MET n 
4 231 GLN n 
4 232 HIS n 
4 233 LEU n 
4 234 GLU n 
4 235 TYR n 
4 236 PRO n 
4 237 LEU n 
4 238 THR n 
4 239 PHE n 
4 240 GLY n 
4 241 ALA n 
4 242 GLY n 
4 243 THR n 
4 244 LYS n 
4 245 LEU n 
4 246 GLU n 
4 247 LEU n 
4 248 LYS n 
4 249 ALA n 
4 250 ALA n 
4 251 ALA n 
4 252 LEU n 
4 253 GLU n 
4 254 VAL n 
4 255 LEU n 
4 256 PHE n 
4 257 GLN n 
4 258 GLY n 
4 259 PRO n 
4 260 HIS n 
4 261 HIS n 
4 262 HIS n 
4 263 HIS n 
4 264 HIS n 
4 265 HIS n 
4 266 HIS n 
4 267 HIS n 
5 1   ASP n 
5 2   TYR n 
5 3   LYS n 
5 4   ASP n 
5 5   ASP n 
5 6   ASP n 
5 7   ASP n 
5 8   ALA n 
5 9   LYS n 
5 10  LEU n 
5 11  GLN n 
5 12  THR n 
5 13  MET n 
5 14  HIS n 
5 15  HIS n 
5 16  HIS n 
5 17  HIS n 
5 18  HIS n 
5 19  HIS n 
5 20  HIS n 
5 21  HIS n 
5 22  HIS n 
5 23  HIS n 
5 24  GLU n 
5 25  ASN n 
5 26  LEU n 
5 27  TYR n 
5 28  PHE n 
5 29  GLN n 
5 30  GLY n 
5 31  GLY n 
5 32  THR n 
5 33  THR n 
5 34  MET n 
5 35  ALA n 
5 36  ASP n 
5 37  LEU n 
5 38  GLU n 
5 39  ASP n 
5 40  ASN n 
5 41  TRP n 
5 42  GLU n 
5 43  THR n 
5 44  LEU n 
5 45  ASN n 
5 46  ASP n 
5 47  ASN n 
5 48  LEU n 
5 49  LYS n 
5 50  VAL n 
5 51  ILE n 
5 52  GLU n 
5 53  LYS n 
5 54  ALA n 
5 55  ASP n 
5 56  ASN n 
5 57  ALA n 
5 58  ALA n 
5 59  GLN n 
5 60  VAL n 
5 61  LYS n 
5 62  ASP n 
5 63  ALA n 
5 64  LEU n 
5 65  THR n 
5 66  LYS n 
5 67  MET n 
5 68  ARG n 
5 69  ALA n 
5 70  ALA n 
5 71  ALA n 
5 72  LEU n 
5 73  ASP n 
5 74  ALA n 
5 75  GLN n 
5 76  LYS n 
5 77  ALA n 
5 78  THR n 
5 79  PRO n 
5 80  PRO n 
5 81  LYS n 
5 82  LEU n 
5 83  GLU n 
5 84  ASP n 
5 85  LYS n 
5 86  SER n 
5 87  PRO n 
5 88  ASP n 
5 89  SER n 
5 90  PRO n 
5 91  GLU n 
5 92  MET n 
5 93  LYS n 
5 94  ASP n 
5 95  PHE n 
5 96  ARG n 
5 97  HIS n 
5 98  GLY n 
5 99  PHE n 
5 100 ASP n 
5 101 ILE n 
5 102 LEU n 
5 103 VAL n 
5 104 GLY n 
5 105 GLN n 
5 106 ILE n 
5 107 ASP n 
5 108 ASP n 
5 109 ALA n 
5 110 LEU n 
5 111 LYS n 
5 112 LEU n 
5 113 ALA n 
5 114 ASN n 
5 115 GLU n 
5 116 GLY n 
5 117 LYS n 
5 118 VAL n 
5 119 LYS n 
5 120 GLU n 
5 121 ALA n 
5 122 GLN n 
5 123 ALA n 
5 124 ALA n 
5 125 ALA n 
5 126 GLU n 
5 127 GLN n 
5 128 LEU n 
5 129 LYS n 
5 130 THR n 
5 131 THR n 
5 132 ARG n 
5 133 ASN n 
5 134 ALA n 
5 135 TYR n 
5 136 ILE n 
5 137 GLN n 
5 138 LYS n 
5 139 TYR n 
5 140 LEU n 
5 141 GLY n 
5 142 SER n 
5 143 THR n 
5 144 LEU n 
5 145 GLU n 
5 146 VAL n 
5 147 LEU n 
5 148 PHE n 
5 149 GLN n 
5 150 GLY n 
5 151 PRO n 
5 152 ASP n 
5 153 PRO n 
5 154 THR n 
5 155 VAL n 
5 156 PRO n 
5 157 VAL n 
5 158 PHE n 
5 159 GLY n 
5 160 THR n 
5 161 LYS n 
5 162 LEU n 
5 163 THR n 
5 164 PRO n 
5 165 ILE n 
5 166 ASN n 
5 167 GLY n 
5 168 ARG n 
5 169 GLU n 
5 170 GLU n 
5 171 THR n 
5 172 PRO n 
5 173 CYS n 
5 174 TYR n 
5 175 ASN n 
5 176 GLN n 
5 177 THR n 
5 178 LEU n 
5 179 SER n 
5 180 PHE n 
5 181 THR n 
5 182 VAL n 
5 183 LEU n 
5 184 THR n 
5 185 CYS n 
5 186 ILE n 
5 187 ILE n 
5 188 SER n 
5 189 LEU n 
5 190 VAL n 
5 191 GLY n 
5 192 LEU n 
5 193 THR n 
5 194 GLY n 
5 195 ASN n 
5 196 ALA n 
5 197 VAL n 
5 198 VAL n 
5 199 LEU n 
5 200 TRP n 
5 201 LEU n 
5 202 LEU n 
5 203 GLY n 
5 204 TYR n 
5 205 ARG n 
5 206 MET n 
5 207 ARG n 
5 208 ARG n 
5 209 ASN n 
5 210 ALA n 
5 211 VAL n 
5 212 SER n 
5 213 ILE n 
5 214 TYR n 
5 215 ILE n 
5 216 LEU n 
5 217 ASN n 
5 218 LEU n 
5 219 ALA n 
5 220 ALA n 
5 221 ALA n 
5 222 ASP n 
5 223 PHE n 
5 224 LEU n 
5 225 PHE n 
5 226 LEU n 
5 227 SER n 
5 228 PHE n 
5 229 GLN n 
5 230 ILE n 
5 231 ILE n 
5 232 ARG n 
5 233 SER n 
5 234 PRO n 
5 235 LEU n 
5 236 ARG n 
5 237 LEU n 
5 238 ILE n 
5 239 ASN n 
5 240 ILE n 
5 241 SER n 
5 242 HIS n 
5 243 LEU n 
5 244 ILE n 
5 245 ARG n 
5 246 LYS n 
5 247 ILE n 
5 248 LEU n 
5 249 VAL n 
5 250 SER n 
5 251 VAL n 
5 252 MET n 
5 253 THR n 
5 254 PHE n 
5 255 PRO n 
5 256 TYR n 
5 257 PHE n 
5 258 THR n 
5 259 GLY n 
5 260 LEU n 
5 261 SER n 
5 262 MET n 
5 263 LEU n 
5 264 SER n 
5 265 ALA n 
5 266 ILE n 
5 267 SER n 
5 268 THR n 
5 269 GLU n 
5 270 ARG n 
5 271 CYS n 
5 272 LEU n 
5 273 SER n 
5 274 VAL n 
5 275 LEU n 
5 276 TRP n 
5 277 PRO n 
5 278 ILE n 
5 279 TRP n 
5 280 TYR n 
5 281 ARG n 
5 282 CYS n 
5 283 ARG n 
5 284 ARG n 
5 285 PRO n 
5 286 THR n 
5 287 HIS n 
5 288 LEU n 
5 289 SER n 
5 290 ALA n 
5 291 VAL n 
5 292 VAL n 
5 293 CYS n 
5 294 VAL n 
5 295 LEU n 
5 296 LEU n 
5 297 TRP n 
5 298 GLY n 
5 299 LEU n 
5 300 SER n 
5 301 LEU n 
5 302 LEU n 
5 303 PHE n 
5 304 SER n 
5 305 MET n 
5 306 LEU n 
5 307 GLU n 
5 308 TRP n 
5 309 ARG n 
5 310 PHE n 
5 311 CYS n 
5 312 ASP n 
5 313 PHE n 
5 314 LEU n 
5 315 PHE n 
5 316 SER n 
5 317 GLY n 
5 318 ALA n 
5 319 ASP n 
5 320 SER n 
5 321 SER n 
5 322 TRP n 
5 323 CYS n 
5 324 GLU n 
5 325 THR n 
5 326 SER n 
5 327 ASP n 
5 328 PHE n 
5 329 ILE n 
5 330 PRO n 
5 331 VAL n 
5 332 ALA n 
5 333 TRP n 
5 334 LEU n 
5 335 ILE n 
5 336 PHE n 
5 337 LEU n 
5 338 CYS n 
5 339 VAL n 
5 340 VAL n 
5 341 LEU n 
5 342 CYS n 
5 343 VAL n 
5 344 SER n 
5 345 SER n 
5 346 LEU n 
5 347 VAL n 
5 348 LEU n 
5 349 LEU n 
5 350 VAL n 
5 351 ARG n 
5 352 ILE n 
5 353 LEU n 
5 354 CYS n 
5 355 GLY n 
5 356 SER n 
5 357 ARG n 
5 358 LYS n 
5 359 MET n 
5 360 PRO n 
5 361 LEU n 
5 362 THR n 
5 363 ARG n 
5 364 LEU n 
5 365 TYR n 
5 366 VAL n 
5 367 THR n 
5 368 ILE n 
5 369 LEU n 
5 370 LEU n 
5 371 THR n 
5 372 VAL n 
5 373 LEU n 
5 374 VAL n 
5 375 PHE n 
5 376 LEU n 
5 377 LEU n 
5 378 CYS n 
5 379 GLY n 
5 380 LEU n 
5 381 PRO n 
5 382 PHE n 
5 383 GLY n 
5 384 ILE n 
5 385 LEU n 
5 386 GLY n 
5 387 ALA n 
5 388 LEU n 
5 389 ILE n 
5 390 TYR n 
5 391 ARG n 
5 392 MET n 
5 393 HIS n 
5 394 LEU n 
5 395 ASN n 
5 396 LEU n 
5 397 GLU n 
5 398 VAL n 
5 399 LEU n 
5 400 TYR n 
5 401 CYS n 
5 402 HIS n 
5 403 VAL n 
5 404 TYR n 
5 405 LEU n 
5 406 VAL n 
5 407 CYS n 
5 408 MET n 
5 409 SER n 
5 410 LEU n 
5 411 SER n 
5 412 SER n 
5 413 LEU n 
5 414 ASN n 
5 415 SER n 
5 416 SER n 
5 417 ALA n 
5 418 ASN n 
5 419 PRO n 
5 420 ILE n 
5 421 ILE n 
5 422 TYR n 
5 423 PHE n 
5 424 PHE n 
5 425 VAL n 
5 426 GLY n 
5 427 SER n 
5 428 PHE n 
5 429 ARG n 
5 430 GLN n 
5 431 ARG n 
5 432 GLN n 
5 433 ASN n 
5 434 ARG n 
5 435 GLN n 
5 436 ASN n 
5 437 LEU n 
5 438 LYS n 
5 439 LEU n 
5 440 VAL n 
5 441 LEU n 
5 442 GLN n 
5 443 ARG n 
5 444 ALA n 
5 445 LEU n 
5 446 GLN n 
5 447 ASP n 
5 448 LYS n 
5 449 PRO n 
5 450 GLU n 
5 451 VAL n 
5 452 ASP n 
5 453 LYS n 
5 454 GLY n 
5 455 GLU n 
5 456 GLY n 
5 457 GLN n 
5 458 LEU n 
5 459 PRO n 
5 460 GLU n 
5 461 GLU n 
5 462 SER n 
5 463 LEU n 
5 464 GLU n 
5 465 LEU n 
5 466 SER n 
5 467 GLY n 
5 468 SER n 
5 469 ARG n 
5 470 LEU n 
5 471 GLY n 
5 472 PRO n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   246 ?     ? ?                              ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   358 human ? GNB1                           ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  human ? GNG2                           ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   267 ?     ? ?                              ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   151 human ? cybC                           ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 152 472 human ? 'MRGPRX4, MRGX4, SNSR5, SNSR6' ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1LZU non-polymer         . '[2,6-di(propan-2-yl)phenoxy]methyl dihydrogen phosphate' ? 'C13 H21 O5 P'   288.277 
ALA   'L-peptide linking' y ALANINE                                                   ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                  ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                           ? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                  ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                 ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                           ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                   ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                                 ? 'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking' y ISOLEUCINE                                                ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                   ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                    ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                             ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                   ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                    ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                                 ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                  ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                    ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1    ?   ?   ?   B . n 
A 1 2   GLY 2   2    ?   ?   ?   B . n 
A 1 3   SER 3   3    ?   ?   ?   B . n 
A 1 4   THR 4   4    4   THR THR B . n 
A 1 5   VAL 5   5    5   VAL VAL B . n 
A 1 6   SER 6   6    6   SER SER B . n 
A 1 7   ALA 7   7    7   ALA ALA B . n 
A 1 8   GLU 8   8    8   GLU GLU B . n 
A 1 9   ASP 9   9    9   ASP ASP B . n 
A 1 10  LYS 10  10   10  LYS LYS B . n 
A 1 11  ALA 11  11   11  ALA ALA B . n 
A 1 12  ALA 12  12   12  ALA ALA B . n 
A 1 13  ALA 13  13   13  ALA ALA B . n 
A 1 14  GLU 14  14   14  GLU GLU B . n 
A 1 15  ARG 15  15   15  ARG ARG B . n 
A 1 16  SER 16  16   16  SER SER B . n 
A 1 17  LYS 17  17   17  LYS LYS B . n 
A 1 18  MET 18  18   18  MET MET B . n 
A 1 19  ILE 19  19   19  ILE ILE B . n 
A 1 20  ASP 20  20   20  ASP ASP B . n 
A 1 21  LYS 21  21   21  LYS LYS B . n 
A 1 22  ASN 22  22   22  ASN ASN B . n 
A 1 23  LEU 23  23   23  LEU LEU B . n 
A 1 24  ARG 24  24   24  ARG ARG B . n 
A 1 25  GLU 25  25   25  GLU GLU B . n 
A 1 26  ASP 26  26   26  ASP ASP B . n 
A 1 27  GLY 27  27   27  GLY GLY B . n 
A 1 28  GLU 28  28   28  GLU GLU B . n 
A 1 29  LYS 29  29   29  LYS LYS B . n 
A 1 30  ALA 30  30   30  ALA ALA B . n 
A 1 31  ARG 31  31   31  ARG ARG B . n 
A 1 32  ARG 32  32   32  ARG ARG B . n 
A 1 33  THR 33  33   33  THR THR B . n 
A 1 34  LEU 34  34   34  LEU LEU B . n 
A 1 35  ARG 35  35   35  ARG ARG B . n 
A 1 36  LEU 36  36   36  LEU LEU B . n 
A 1 37  LEU 37  37   37  LEU LEU B . n 
A 1 38  LEU 38  38   38  LEU LEU B . n 
A 1 39  LEU 39  39   39  LEU LEU B . n 
A 1 40  GLY 40  40   40  GLY GLY B . n 
A 1 41  ALA 41  41   41  ALA ALA B . n 
A 1 42  ASP 42  42   42  ASP ASP B . n 
A 1 43  ASN 43  43   43  ASN ASN B . n 
A 1 44  SER 44  44   44  SER SER B . n 
A 1 45  GLY 45  45   45  GLY GLY B . n 
A 1 46  LYS 46  46   46  LYS LYS B . n 
A 1 47  SER 47  47   47  SER SER B . n 
A 1 48  THR 48  48   48  THR THR B . n 
A 1 49  ILE 49  49   49  ILE ILE B . n 
A 1 50  VAL 50  50   50  VAL VAL B . n 
A 1 51  LYS 51  51   51  LYS LYS B . n 
A 1 52  GLN 52  52   ?   ?   ?   B . n 
A 1 53  MET 53  53   ?   ?   ?   B . n 
A 1 54  ARG 54  54   ?   ?   ?   B . n 
A 1 55  ILE 55  55   ?   ?   ?   B . n 
A 1 56  LEU 56  56   ?   ?   ?   B . n 
A 1 57  HIS 57  57   ?   ?   ?   B . n 
A 1 58  GLY 58  58   ?   ?   ?   B . n 
A 1 59  GLY 59  59   ?   ?   ?   B . n 
A 1 60  SER 60  60   ?   ?   ?   B . n 
A 1 61  GLY 61  61   ?   ?   ?   B . n 
A 1 62  GLY 62  62   ?   ?   ?   B . n 
A 1 63  SER 63  63   ?   ?   ?   B . n 
A 1 64  GLY 64  64   ?   ?   ?   B . n 
A 1 65  GLY 65  65   ?   ?   ?   B . n 
A 1 66  THR 66  66   ?   ?   ?   B . n 
A 1 67  SER 67  67   ?   ?   ?   B . n 
A 1 68  GLY 68  68   68  GLY GLY B . n 
A 1 69  ILE 69  69   69  ILE ILE B . n 
A 1 70  PHE 70  70   70  PHE PHE B . n 
A 1 71  GLU 71  71   71  GLU GLU B . n 
A 1 72  THR 72  72   72  THR THR B . n 
A 1 73  LYS 73  73   73  LYS LYS B . n 
A 1 74  PHE 74  74   74  PHE PHE B . n 
A 1 75  GLN 75  75   75  GLN GLN B . n 
A 1 76  VAL 76  76   76  VAL VAL B . n 
A 1 77  ASP 77  77   77  ASP ASP B . n 
A 1 78  LYS 78  78   78  LYS LYS B . n 
A 1 79  VAL 79  79   79  VAL VAL B . n 
A 1 80  ASN 80  80   80  ASN ASN B . n 
A 1 81  PHE 81  81   81  PHE PHE B . n 
A 1 82  HIS 82  82   82  HIS HIS B . n 
A 1 83  MET 83  83   83  MET MET B . n 
A 1 84  PHE 84  84   84  PHE PHE B . n 
A 1 85  ASP 85  85   85  ASP ASP B . n 
A 1 86  VAL 86  86   86  VAL VAL B . n 
A 1 87  GLY 87  87   87  GLY GLY B . n 
A 1 88  GLY 88  88   ?   ?   ?   B . n 
A 1 89  GLN 89  89   ?   ?   ?   B . n 
A 1 90  ARG 90  90   ?   ?   ?   B . n 
A 1 91  ASP 91  91   ?   ?   ?   B . n 
A 1 92  GLU 92  92   ?   ?   ?   B . n 
A 1 93  ARG 93  93   93  ARG ARG B . n 
A 1 94  ARG 94  94   94  ARG ARG B . n 
A 1 95  LYS 95  95   95  LYS LYS B . n 
A 1 96  TRP 96  96   96  TRP TRP B . n 
A 1 97  ILE 97  97   97  ILE ILE B . n 
A 1 98  GLN 98  98   98  GLN GLN B . n 
A 1 99  CYS 99  99   99  CYS CYS B . n 
A 1 100 PHE 100 100  100 PHE PHE B . n 
A 1 101 ASN 101 101  101 ASN ASN B . n 
A 1 102 ASP 102 102  102 ASP ASP B . n 
A 1 103 VAL 103 103  103 VAL VAL B . n 
A 1 104 THR 104 104  104 THR THR B . n 
A 1 105 ALA 105 105  105 ALA ALA B . n 
A 1 106 ILE 106 106  106 ILE ILE B . n 
A 1 107 ILE 107 107  107 ILE ILE B . n 
A 1 108 PHE 108 108  108 PHE PHE B . n 
A 1 109 VAL 109 109  109 VAL VAL B . n 
A 1 110 VAL 110 110  110 VAL VAL B . n 
A 1 111 ASP 111 111  111 ASP ASP B . n 
A 1 112 SER 112 112  112 SER SER B . n 
A 1 113 SER 113 113  113 SER SER B . n 
A 1 114 ASP 114 114  114 ASP ASP B . n 
A 1 115 TYR 115 115  115 TYR TYR B . n 
A 1 116 ASN 116 116  116 ASN ASN B . n 
A 1 117 ARG 117 117  117 ARG ARG B . n 
A 1 118 LEU 118 118  118 LEU LEU B . n 
A 1 119 GLN 119 119  119 GLN GLN B . n 
A 1 120 GLU 120 120  120 GLU GLU B . n 
A 1 121 ALA 121 121  121 ALA ALA B . n 
A 1 122 LEU 122 122  122 LEU LEU B . n 
A 1 123 ASN 123 123  123 ASN ASN B . n 
A 1 124 ASP 124 124  124 ASP ASP B . n 
A 1 125 PHE 125 125  125 PHE PHE B . n 
A 1 126 LYS 126 126  126 LYS LYS B . n 
A 1 127 SER 127 127  127 SER SER B . n 
A 1 128 ILE 128 128  128 ILE ILE B . n 
A 1 129 TRP 129 129  129 TRP TRP B . n 
A 1 130 ASN 130 130  130 ASN ASN B . n 
A 1 131 ASN 131 131  131 ASN ASN B . n 
A 1 132 ARG 132 132  132 ARG ARG B . n 
A 1 133 TRP 133 133  133 TRP TRP B . n 
A 1 134 LEU 134 134  134 LEU LEU B . n 
A 1 135 ARG 135 135  135 ARG ARG B . n 
A 1 136 THR 136 136  136 THR THR B . n 
A 1 137 ILE 137 137  137 ILE ILE B . n 
A 1 138 SER 138 138  138 SER SER B . n 
A 1 139 VAL 139 139  139 VAL VAL B . n 
A 1 140 ILE 140 140  140 ILE ILE B . n 
A 1 141 LEU 141 141  141 LEU LEU B . n 
A 1 142 PHE 142 142  142 PHE PHE B . n 
A 1 143 LEU 143 143  143 LEU LEU B . n 
A 1 144 ASN 144 144  144 ASN ASN B . n 
A 1 145 LYS 145 145  145 LYS LYS B . n 
A 1 146 GLN 146 146  146 GLN GLN B . n 
A 1 147 ASP 147 147  147 ASP ASP B . n 
A 1 148 LEU 148 148  148 LEU LEU B . n 
A 1 149 LEU 149 149  149 LEU LEU B . n 
A 1 150 ALA 150 150  150 ALA ALA B . n 
A 1 151 GLU 151 151  151 GLU GLU B . n 
A 1 152 LYS 152 152  152 LYS LYS B . n 
A 1 153 VAL 153 153  153 VAL VAL B . n 
A 1 154 LEU 154 154  154 LEU LEU B . n 
A 1 155 ALA 155 155  155 ALA ALA B . n 
A 1 156 GLY 156 156  156 GLY GLY B . n 
A 1 157 LYS 157 157  157 LYS LYS B . n 
A 1 158 SER 158 158  158 SER SER B . n 
A 1 159 LYS 159 159  159 LYS LYS B . n 
A 1 160 ILE 160 160  160 ILE ILE B . n 
A 1 161 GLU 161 161  161 GLU GLU B . n 
A 1 162 ASP 162 162  162 ASP ASP B . n 
A 1 163 TYR 163 163  163 TYR TYR B . n 
A 1 164 PHE 164 164  164 PHE PHE B . n 
A 1 165 PRO 165 165  165 PRO PRO B . n 
A 1 166 GLU 166 166  166 GLU GLU B . n 
A 1 167 PHE 167 167  167 PHE PHE B . n 
A 1 168 ALA 168 168  168 ALA ALA B . n 
A 1 169 ARG 169 169  169 ARG ARG B . n 
A 1 170 TYR 170 170  170 TYR TYR B . n 
A 1 171 THR 171 171  171 THR THR B . n 
A 1 172 THR 172 172  172 THR THR B . n 
A 1 173 PRO 173 173  173 PRO PRO B . n 
A 1 174 GLU 174 174  174 GLU GLU B . n 
A 1 175 ASP 175 175  175 ASP ASP B . n 
A 1 176 ALA 176 176  176 ALA ALA B . n 
A 1 177 THR 177 177  177 THR THR B . n 
A 1 178 PRO 178 178  178 PRO PRO B . n 
A 1 179 GLU 179 179  179 GLU GLU B . n 
A 1 180 PRO 180 180  180 PRO PRO B . n 
A 1 181 GLY 181 181  181 GLY GLY B . n 
A 1 182 GLU 182 182  182 GLU GLU B . n 
A 1 183 ASP 183 183  183 ASP ASP B . n 
A 1 184 PRO 184 184  184 PRO PRO B . n 
A 1 185 ARG 185 185  185 ARG ARG B . n 
A 1 186 VAL 186 186  186 VAL VAL B . n 
A 1 187 THR 187 187  187 THR THR B . n 
A 1 188 ARG 188 188  188 ARG ARG B . n 
A 1 189 ALA 189 189  189 ALA ALA B . n 
A 1 190 LYS 190 190  190 LYS LYS B . n 
A 1 191 TYR 191 191  191 TYR TYR B . n 
A 1 192 PHE 192 192  192 PHE PHE B . n 
A 1 193 ILE 193 193  193 ILE ILE B . n 
A 1 194 ARG 194 194  194 ARG ARG B . n 
A 1 195 LYS 195 195  195 LYS LYS B . n 
A 1 196 GLU 196 196  196 GLU GLU B . n 
A 1 197 PHE 197 197  197 PHE PHE B . n 
A 1 198 VAL 198 198  198 VAL VAL B . n 
A 1 199 ASP 199 199  199 ASP ASP B . n 
A 1 200 ILE 200 200  200 ILE ILE B . n 
A 1 201 SER 201 201  201 SER SER B . n 
A 1 202 THR 202 202  202 THR THR B . n 
A 1 203 ALA 203 203  203 ALA ALA B . n 
A 1 204 SER 204 204  204 SER SER B . n 
A 1 205 GLY 205 205  205 GLY GLY B . n 
A 1 206 ASP 206 206  206 ASP ASP B . n 
A 1 207 GLY 207 207  207 GLY GLY B . n 
A 1 208 ARG 208 208  208 ARG ARG B . n 
A 1 209 HIS 209 209  209 HIS HIS B . n 
A 1 210 ILE 210 210  210 ILE ILE B . n 
A 1 211 CYS 211 211  211 CYS CYS B . n 
A 1 212 TYR 212 212  212 TYR TYR B . n 
A 1 213 PRO 213 213  213 PRO PRO B . n 
A 1 214 HIS 214 214  214 HIS HIS B . n 
A 1 215 PHE 215 215  215 PHE PHE B . n 
A 1 216 THR 216 216  216 THR THR B . n 
A 1 217 CYS 217 217  217 CYS CYS B . n 
A 1 218 ALA 218 218  218 ALA ALA B . n 
A 1 219 VAL 219 219  219 VAL VAL B . n 
A 1 220 ASP 220 220  220 ASP ASP B . n 
A 1 221 THR 221 221  221 THR THR B . n 
A 1 222 GLU 222 222  222 GLU GLU B . n 
A 1 223 ASN 223 223  223 ASN ASN B . n 
A 1 224 ALA 224 224  224 ALA ALA B . n 
A 1 225 ARG 225 225  225 ARG ARG B . n 
A 1 226 ARG 226 226  226 ARG ARG B . n 
A 1 227 ILE 227 227  227 ILE ILE B . n 
A 1 228 PHE 228 228  228 PHE PHE B . n 
A 1 229 ASN 229 229  229 ASN ASN B . n 
A 1 230 ASP 230 230  230 ASP ASP B . n 
A 1 231 CYS 231 231  231 CYS CYS B . n 
A 1 232 LYS 232 232  232 LYS LYS B . n 
A 1 233 ASP 233 233  233 ASP ASP B . n 
A 1 234 ILE 234 234  234 ILE ILE B . n 
A 1 235 ILE 235 235  235 ILE ILE B . n 
A 1 236 LEU 236 236  236 LEU LEU B . n 
A 1 237 GLN 237 237  237 GLN GLN B . n 
A 1 238 MET 238 238  238 MET MET B . n 
A 1 239 ASN 239 239  239 ASN ASN B . n 
A 1 240 LEU 240 240  240 LEU LEU B . n 
A 1 241 ARG 241 241  241 ARG ARG B . n 
A 1 242 GLU 242 242  242 GLU GLU B . n 
A 1 243 TYR 243 243  243 TYR TYR B . n 
A 1 244 ASN 244 244  244 ASN ASN B . n 
A 1 245 LEU 245 245  245 LEU LEU B . n 
A 1 246 VAL 246 246  246 VAL VAL B . n 
B 2 1   MET 1   -17  ?   ?   ?   C . n 
B 2 2   HIS 2   -16  ?   ?   ?   C . n 
B 2 3   HIS 3   -15  ?   ?   ?   C . n 
B 2 4   HIS 4   -14  ?   ?   ?   C . n 
B 2 5   HIS 5   -13  ?   ?   ?   C . n 
B 2 6   HIS 6   -12  ?   ?   ?   C . n 
B 2 7   HIS 7   -11  ?   ?   ?   C . n 
B 2 8   LEU 8   -10  ?   ?   ?   C . n 
B 2 9   GLU 9   -9   ?   ?   ?   C . n 
B 2 10  VAL 10  -8   ?   ?   ?   C . n 
B 2 11  LEU 11  -7   ?   ?   ?   C . n 
B 2 12  PHE 12  -6   ?   ?   ?   C . n 
B 2 13  GLN 13  -5   ?   ?   ?   C . n 
B 2 14  GLY 14  -4   ?   ?   ?   C . n 
B 2 15  PRO 15  -3   ?   ?   ?   C . n 
B 2 16  GLY 16  -2   ?   ?   ?   C . n 
B 2 17  SER 17  -1   ?   ?   ?   C . n 
B 2 18  SER 18  0    ?   ?   ?   C . n 
B 2 19  GLY 19  1    ?   ?   ?   C . n 
B 2 20  SER 20  2    ?   ?   ?   C . n 
B 2 21  GLU 21  3    3   GLU GLU C . n 
B 2 22  LEU 22  4    4   LEU LEU C . n 
B 2 23  ASP 23  5    5   ASP ASP C . n 
B 2 24  GLN 24  6    6   GLN GLN C . n 
B 2 25  LEU 25  7    7   LEU LEU C . n 
B 2 26  ARG 26  8    8   ARG ARG C . n 
B 2 27  GLN 27  9    9   GLN GLN C . n 
B 2 28  GLU 28  10   10  GLU GLU C . n 
B 2 29  ALA 29  11   11  ALA ALA C . n 
B 2 30  GLU 30  12   12  GLU GLU C . n 
B 2 31  GLN 31  13   13  GLN GLN C . n 
B 2 32  LEU 32  14   14  LEU LEU C . n 
B 2 33  LYS 33  15   15  LYS LYS C . n 
B 2 34  ASN 34  16   16  ASN ASN C . n 
B 2 35  GLN 35  17   17  GLN GLN C . n 
B 2 36  ILE 36  18   18  ILE ILE C . n 
B 2 37  ARG 37  19   19  ARG ARG C . n 
B 2 38  ASP 38  20   20  ASP ASP C . n 
B 2 39  ALA 39  21   21  ALA ALA C . n 
B 2 40  ARG 40  22   22  ARG ARG C . n 
B 2 41  LYS 41  23   23  LYS LYS C . n 
B 2 42  ALA 42  24   24  ALA ALA C . n 
B 2 43  CYS 43  25   25  CYS CYS C . n 
B 2 44  ALA 44  26   26  ALA ALA C . n 
B 2 45  ASP 45  27   27  ASP ASP C . n 
B 2 46  ALA 46  28   28  ALA ALA C . n 
B 2 47  THR 47  29   29  THR THR C . n 
B 2 48  LEU 48  30   30  LEU LEU C . n 
B 2 49  SER 49  31   31  SER SER C . n 
B 2 50  GLN 50  32   32  GLN GLN C . n 
B 2 51  ILE 51  33   33  ILE ILE C . n 
B 2 52  THR 52  34   34  THR THR C . n 
B 2 53  ASN 53  35   35  ASN ASN C . n 
B 2 54  ASN 54  36   36  ASN ASN C . n 
B 2 55  ILE 55  37   37  ILE ILE C . n 
B 2 56  ASP 56  38   38  ASP ASP C . n 
B 2 57  PRO 57  39   39  PRO PRO C . n 
B 2 58  VAL 58  40   40  VAL VAL C . n 
B 2 59  GLY 59  41   41  GLY GLY C . n 
B 2 60  ARG 60  42   42  ARG ARG C . n 
B 2 61  ILE 61  43   43  ILE ILE C . n 
B 2 62  GLN 62  44   44  GLN GLN C . n 
B 2 63  MET 63  45   45  MET MET C . n 
B 2 64  ARG 64  46   46  ARG ARG C . n 
B 2 65  THR 65  47   47  THR THR C . n 
B 2 66  ARG 66  48   48  ARG ARG C . n 
B 2 67  ARG 67  49   49  ARG ARG C . n 
B 2 68  THR 68  50   50  THR THR C . n 
B 2 69  LEU 69  51   51  LEU LEU C . n 
B 2 70  ARG 70  52   52  ARG ARG C . n 
B 2 71  GLY 71  53   53  GLY GLY C . n 
B 2 72  HIS 72  54   54  HIS HIS C . n 
B 2 73  LEU 73  55   55  LEU LEU C . n 
B 2 74  ALA 74  56   56  ALA ALA C . n 
B 2 75  LYS 75  57   57  LYS LYS C . n 
B 2 76  ILE 76  58   58  ILE ILE C . n 
B 2 77  TYR 77  59   59  TYR TYR C . n 
B 2 78  ALA 78  60   60  ALA ALA C . n 
B 2 79  MET 79  61   61  MET MET C . n 
B 2 80  HIS 80  62   62  HIS HIS C . n 
B 2 81  TRP 81  63   63  TRP TRP C . n 
B 2 82  GLY 82  64   64  GLY GLY C . n 
B 2 83  THR 83  65   65  THR THR C . n 
B 2 84  ASP 84  66   66  ASP ASP C . n 
B 2 85  SER 85  67   67  SER SER C . n 
B 2 86  ARG 86  68   68  ARG ARG C . n 
B 2 87  LEU 87  69   69  LEU LEU C . n 
B 2 88  LEU 88  70   70  LEU LEU C . n 
B 2 89  VAL 89  71   71  VAL VAL C . n 
B 2 90  SER 90  72   72  SER SER C . n 
B 2 91  ALA 91  73   73  ALA ALA C . n 
B 2 92  SER 92  74   74  SER SER C . n 
B 2 93  GLN 93  75   75  GLN GLN C . n 
B 2 94  ASP 94  76   76  ASP ASP C . n 
B 2 95  GLY 95  77   77  GLY GLY C . n 
B 2 96  LYS 96  78   78  LYS LYS C . n 
B 2 97  LEU 97  79   79  LEU LEU C . n 
B 2 98  ILE 98  80   80  ILE ILE C . n 
B 2 99  ILE 99  81   81  ILE ILE C . n 
B 2 100 TRP 100 82   82  TRP TRP C . n 
B 2 101 ASP 101 83   83  ASP ASP C . n 
B 2 102 SER 102 84   84  SER SER C . n 
B 2 103 TYR 103 85   85  TYR TYR C . n 
B 2 104 THR 104 86   86  THR THR C . n 
B 2 105 THR 105 87   87  THR THR C . n 
B 2 106 ASN 106 88   88  ASN ASN C . n 
B 2 107 LYS 107 89   89  LYS LYS C . n 
B 2 108 VAL 108 90   90  VAL VAL C . n 
B 2 109 HIS 109 91   91  HIS HIS C . n 
B 2 110 ALA 110 92   92  ALA ALA C . n 
B 2 111 ILE 111 93   93  ILE ILE C . n 
B 2 112 PRO 112 94   94  PRO PRO C . n 
B 2 113 LEU 113 95   95  LEU LEU C . n 
B 2 114 ARG 114 96   96  ARG ARG C . n 
B 2 115 SER 115 97   97  SER SER C . n 
B 2 116 SER 116 98   98  SER SER C . n 
B 2 117 TRP 117 99   99  TRP TRP C . n 
B 2 118 VAL 118 100  100 VAL VAL C . n 
B 2 119 MET 119 101  101 MET MET C . n 
B 2 120 THR 120 102  102 THR THR C . n 
B 2 121 CYS 121 103  103 CYS CYS C . n 
B 2 122 ALA 122 104  104 ALA ALA C . n 
B 2 123 TYR 123 105  105 TYR TYR C . n 
B 2 124 ALA 124 106  106 ALA ALA C . n 
B 2 125 PRO 125 107  107 PRO PRO C . n 
B 2 126 SER 126 108  108 SER SER C . n 
B 2 127 GLY 127 109  109 GLY GLY C . n 
B 2 128 ASN 128 110  110 ASN ASN C . n 
B 2 129 TYR 129 111  111 TYR TYR C . n 
B 2 130 VAL 130 112  112 VAL VAL C . n 
B 2 131 ALA 131 113  113 ALA ALA C . n 
B 2 132 CYS 132 114  114 CYS CYS C . n 
B 2 133 GLY 133 115  115 GLY GLY C . n 
B 2 134 GLY 134 116  116 GLY GLY C . n 
B 2 135 LEU 135 117  117 LEU LEU C . n 
B 2 136 ASP 136 118  118 ASP ASP C . n 
B 2 137 ASN 137 119  119 ASN ASN C . n 
B 2 138 ILE 138 120  120 ILE ILE C . n 
B 2 139 CYS 139 121  121 CYS CYS C . n 
B 2 140 SER 140 122  122 SER SER C . n 
B 2 141 ILE 141 123  123 ILE ILE C . n 
B 2 142 TYR 142 124  124 TYR TYR C . n 
B 2 143 ASN 143 125  125 ASN ASN C . n 
B 2 144 LEU 144 126  126 LEU LEU C . n 
B 2 145 LYS 145 127  127 LYS LYS C . n 
B 2 146 THR 146 128  128 THR THR C . n 
B 2 147 ARG 147 129  129 ARG ARG C . n 
B 2 148 GLU 148 130  130 GLU GLU C . n 
B 2 149 GLY 149 131  131 GLY GLY C . n 
B 2 150 ASN 150 132  132 ASN ASN C . n 
B 2 151 VAL 151 133  133 VAL VAL C . n 
B 2 152 ARG 152 134  134 ARG ARG C . n 
B 2 153 VAL 153 135  135 VAL VAL C . n 
B 2 154 SER 154 136  136 SER SER C . n 
B 2 155 ARG 155 137  137 ARG ARG C . n 
B 2 156 GLU 156 138  138 GLU GLU C . n 
B 2 157 LEU 157 139  139 LEU LEU C . n 
B 2 158 ALA 158 140  140 ALA ALA C . n 
B 2 159 GLY 159 141  141 GLY GLY C . n 
B 2 160 HIS 160 142  142 HIS HIS C . n 
B 2 161 THR 161 143  143 THR THR C . n 
B 2 162 GLY 162 144  144 GLY GLY C . n 
B 2 163 TYR 163 145  145 TYR TYR C . n 
B 2 164 LEU 164 146  146 LEU LEU C . n 
B 2 165 SER 165 147  147 SER SER C . n 
B 2 166 CYS 166 148  148 CYS CYS C . n 
B 2 167 CYS 167 149  149 CYS CYS C . n 
B 2 168 ARG 168 150  150 ARG ARG C . n 
B 2 169 PHE 169 151  151 PHE PHE C . n 
B 2 170 LEU 170 152  152 LEU LEU C . n 
B 2 171 ASP 171 153  153 ASP ASP C . n 
B 2 172 ASP 172 154  154 ASP ASP C . n 
B 2 173 ASN 173 155  155 ASN ASN C . n 
B 2 174 GLN 174 156  156 GLN GLN C . n 
B 2 175 ILE 175 157  157 ILE ILE C . n 
B 2 176 VAL 176 158  158 VAL VAL C . n 
B 2 177 THR 177 159  159 THR THR C . n 
B 2 178 SER 178 160  160 SER SER C . n 
B 2 179 SER 179 161  161 SER SER C . n 
B 2 180 GLY 180 162  162 GLY GLY C . n 
B 2 181 ASP 181 163  163 ASP ASP C . n 
B 2 182 THR 182 164  164 THR THR C . n 
B 2 183 THR 183 165  165 THR THR C . n 
B 2 184 CYS 184 166  166 CYS CYS C . n 
B 2 185 ALA 185 167  167 ALA ALA C . n 
B 2 186 LEU 186 168  168 LEU LEU C . n 
B 2 187 TRP 187 169  169 TRP TRP C . n 
B 2 188 ASP 188 170  170 ASP ASP C . n 
B 2 189 ILE 189 171  171 ILE ILE C . n 
B 2 190 GLU 190 172  172 GLU GLU C . n 
B 2 191 THR 191 173  173 THR THR C . n 
B 2 192 GLY 192 174  174 GLY GLY C . n 
B 2 193 GLN 193 175  175 GLN GLN C . n 
B 2 194 GLN 194 176  176 GLN GLN C . n 
B 2 195 THR 195 177  177 THR THR C . n 
B 2 196 THR 196 178  178 THR THR C . n 
B 2 197 THR 197 179  179 THR THR C . n 
B 2 198 PHE 198 180  180 PHE PHE C . n 
B 2 199 THR 199 181  181 THR THR C . n 
B 2 200 GLY 200 182  182 GLY GLY C . n 
B 2 201 HIS 201 183  183 HIS HIS C . n 
B 2 202 THR 202 184  184 THR THR C . n 
B 2 203 GLY 203 185  185 GLY GLY C . n 
B 2 204 ASP 204 186  186 ASP ASP C . n 
B 2 205 VAL 205 187  187 VAL VAL C . n 
B 2 206 MET 206 188  188 MET MET C . n 
B 2 207 SER 207 189  189 SER SER C . n 
B 2 208 LEU 208 190  190 LEU LEU C . n 
B 2 209 SER 209 191  191 SER SER C . n 
B 2 210 LEU 210 192  192 LEU LEU C . n 
B 2 211 ALA 211 193  193 ALA ALA C . n 
B 2 212 PRO 212 194  194 PRO PRO C . n 
B 2 213 ASP 213 195  195 ASP ASP C . n 
B 2 214 THR 214 196  196 THR THR C . n 
B 2 215 ARG 215 197  197 ARG ARG C . n 
B 2 216 LEU 216 198  198 LEU LEU C . n 
B 2 217 PHE 217 199  199 PHE PHE C . n 
B 2 218 VAL 218 200  200 VAL VAL C . n 
B 2 219 SER 219 201  201 SER SER C . n 
B 2 220 GLY 220 202  202 GLY GLY C . n 
B 2 221 ALA 221 203  203 ALA ALA C . n 
B 2 222 CYS 222 204  204 CYS CYS C . n 
B 2 223 ASP 223 205  205 ASP ASP C . n 
B 2 224 ALA 224 206  206 ALA ALA C . n 
B 2 225 SER 225 207  207 SER SER C . n 
B 2 226 ALA 226 208  208 ALA ALA C . n 
B 2 227 LYS 227 209  209 LYS LYS C . n 
B 2 228 LEU 228 210  210 LEU LEU C . n 
B 2 229 TRP 229 211  211 TRP TRP C . n 
B 2 230 ASP 230 212  212 ASP ASP C . n 
B 2 231 VAL 231 213  213 VAL VAL C . n 
B 2 232 ARG 232 214  214 ARG ARG C . n 
B 2 233 GLU 233 215  215 GLU GLU C . n 
B 2 234 GLY 234 216  216 GLY GLY C . n 
B 2 235 MET 235 217  217 MET MET C . n 
B 2 236 CYS 236 218  218 CYS CYS C . n 
B 2 237 ARG 237 219  219 ARG ARG C . n 
B 2 238 GLN 238 220  220 GLN GLN C . n 
B 2 239 THR 239 221  221 THR THR C . n 
B 2 240 PHE 240 222  222 PHE PHE C . n 
B 2 241 THR 241 223  223 THR THR C . n 
B 2 242 GLY 242 224  224 GLY GLY C . n 
B 2 243 HIS 243 225  225 HIS HIS C . n 
B 2 244 GLU 244 226  226 GLU GLU C . n 
B 2 245 SER 245 227  227 SER SER C . n 
B 2 246 ASP 246 228  228 ASP ASP C . n 
B 2 247 ILE 247 229  229 ILE ILE C . n 
B 2 248 ASN 248 230  230 ASN ASN C . n 
B 2 249 ALA 249 231  231 ALA ALA C . n 
B 2 250 ILE 250 232  232 ILE ILE C . n 
B 2 251 CYS 251 233  233 CYS CYS C . n 
B 2 252 PHE 252 234  234 PHE PHE C . n 
B 2 253 PHE 253 235  235 PHE PHE C . n 
B 2 254 PRO 254 236  236 PRO PRO C . n 
B 2 255 ASN 255 237  237 ASN ASN C . n 
B 2 256 GLY 256 238  238 GLY GLY C . n 
B 2 257 ASN 257 239  239 ASN ASN C . n 
B 2 258 ALA 258 240  240 ALA ALA C . n 
B 2 259 PHE 259 241  241 PHE PHE C . n 
B 2 260 ALA 260 242  242 ALA ALA C . n 
B 2 261 THR 261 243  243 THR THR C . n 
B 2 262 GLY 262 244  244 GLY GLY C . n 
B 2 263 SER 263 245  245 SER SER C . n 
B 2 264 ASP 264 246  246 ASP ASP C . n 
B 2 265 ASP 265 247  247 ASP ASP C . n 
B 2 266 ALA 266 248  248 ALA ALA C . n 
B 2 267 THR 267 249  249 THR THR C . n 
B 2 268 CYS 268 250  250 CYS CYS C . n 
B 2 269 ARG 269 251  251 ARG ARG C . n 
B 2 270 LEU 270 252  252 LEU LEU C . n 
B 2 271 PHE 271 253  253 PHE PHE C . n 
B 2 272 ASP 272 254  254 ASP ASP C . n 
B 2 273 LEU 273 255  255 LEU LEU C . n 
B 2 274 ARG 274 256  256 ARG ARG C . n 
B 2 275 ALA 275 257  257 ALA ALA C . n 
B 2 276 ASP 276 258  258 ASP ASP C . n 
B 2 277 GLN 277 259  259 GLN GLN C . n 
B 2 278 GLU 278 260  260 GLU GLU C . n 
B 2 279 LEU 279 261  261 LEU LEU C . n 
B 2 280 MET 280 262  262 MET MET C . n 
B 2 281 THR 281 263  263 THR THR C . n 
B 2 282 TYR 282 264  264 TYR TYR C . n 
B 2 283 SER 283 265  265 SER SER C . n 
B 2 284 HIS 284 266  266 HIS HIS C . n 
B 2 285 ASP 285 267  267 ASP ASP C . n 
B 2 286 ASN 286 268  268 ASN ASN C . n 
B 2 287 ILE 287 269  269 ILE ILE C . n 
B 2 288 ILE 288 270  270 ILE ILE C . n 
B 2 289 CYS 289 271  271 CYS CYS C . n 
B 2 290 GLY 290 272  272 GLY GLY C . n 
B 2 291 ILE 291 273  273 ILE ILE C . n 
B 2 292 THR 292 274  274 THR THR C . n 
B 2 293 SER 293 275  275 SER SER C . n 
B 2 294 VAL 294 276  276 VAL VAL C . n 
B 2 295 SER 295 277  277 SER SER C . n 
B 2 296 PHE 296 278  278 PHE PHE C . n 
B 2 297 SER 297 279  279 SER SER C . n 
B 2 298 LYS 298 280  280 LYS LYS C . n 
B 2 299 SER 299 281  281 SER SER C . n 
B 2 300 GLY 300 282  282 GLY GLY C . n 
B 2 301 ARG 301 283  283 ARG ARG C . n 
B 2 302 LEU 302 284  284 LEU LEU C . n 
B 2 303 LEU 303 285  285 LEU LEU C . n 
B 2 304 LEU 304 286  286 LEU LEU C . n 
B 2 305 ALA 305 287  287 ALA ALA C . n 
B 2 306 GLY 306 288  288 GLY GLY C . n 
B 2 307 TYR 307 289  289 TYR TYR C . n 
B 2 308 ASP 308 290  290 ASP ASP C . n 
B 2 309 ASP 309 291  291 ASP ASP C . n 
B 2 310 PHE 310 292  292 PHE PHE C . n 
B 2 311 ASN 311 293  293 ASN ASN C . n 
B 2 312 CYS 312 294  294 CYS CYS C . n 
B 2 313 ASN 313 295  295 ASN ASN C . n 
B 2 314 VAL 314 296  296 VAL VAL C . n 
B 2 315 TRP 315 297  297 TRP TRP C . n 
B 2 316 ASP 316 298  298 ASP ASP C . n 
B 2 317 ALA 317 299  299 ALA ALA C . n 
B 2 318 LEU 318 300  300 LEU LEU C . n 
B 2 319 LYS 319 301  301 LYS LYS C . n 
B 2 320 ALA 320 302  302 ALA ALA C . n 
B 2 321 ASP 321 303  303 ASP ASP C . n 
B 2 322 ARG 322 304  304 ARG ARG C . n 
B 2 323 ALA 323 305  305 ALA ALA C . n 
B 2 324 GLY 324 306  306 GLY GLY C . n 
B 2 325 VAL 325 307  307 VAL VAL C . n 
B 2 326 LEU 326 308  308 LEU LEU C . n 
B 2 327 ALA 327 309  309 ALA ALA C . n 
B 2 328 GLY 328 310  310 GLY GLY C . n 
B 2 329 HIS 329 311  311 HIS HIS C . n 
B 2 330 ASP 330 312  312 ASP ASP C . n 
B 2 331 ASN 331 313  313 ASN ASN C . n 
B 2 332 ARG 332 314  314 ARG ARG C . n 
B 2 333 VAL 333 315  315 VAL VAL C . n 
B 2 334 SER 334 316  316 SER SER C . n 
B 2 335 CYS 335 317  317 CYS CYS C . n 
B 2 336 LEU 336 318  318 LEU LEU C . n 
B 2 337 GLY 337 319  319 GLY GLY C . n 
B 2 338 VAL 338 320  320 VAL VAL C . n 
B 2 339 THR 339 321  321 THR THR C . n 
B 2 340 ASP 340 322  322 ASP ASP C . n 
B 2 341 ASP 341 323  323 ASP ASP C . n 
B 2 342 GLY 342 324  324 GLY GLY C . n 
B 2 343 MET 343 325  325 MET MET C . n 
B 2 344 ALA 344 326  326 ALA ALA C . n 
B 2 345 VAL 345 327  327 VAL VAL C . n 
B 2 346 ALA 346 328  328 ALA ALA C . n 
B 2 347 THR 347 329  329 THR THR C . n 
B 2 348 GLY 348 330  330 GLY GLY C . n 
B 2 349 SER 349 331  331 SER SER C . n 
B 2 350 TRP 350 332  332 TRP TRP C . n 
B 2 351 ASP 351 333  333 ASP ASP C . n 
B 2 352 SER 352 334  334 SER SER C . n 
B 2 353 PHE 353 335  335 PHE PHE C . n 
B 2 354 LEU 354 336  336 LEU LEU C . n 
B 2 355 LYS 355 337  337 LYS LYS C . n 
B 2 356 ILE 356 338  338 ILE ILE C . n 
B 2 357 TRP 357 339  339 TRP TRP C . n 
B 2 358 ASN 358 340  340 ASN ASN C . n 
C 3 1   MET 1   1    ?   ?   ?   D . n 
C 3 2   ALA 2   2    ?   ?   ?   D . n 
C 3 3   SER 3   3    ?   ?   ?   D . n 
C 3 4   ASN 4   4    ?   ?   ?   D . n 
C 3 5   ASN 5   5    ?   ?   ?   D . n 
C 3 6   THR 6   6    ?   ?   ?   D . n 
C 3 7   ALA 7   7    ?   ?   ?   D . n 
C 3 8   SER 8   8    ?   ?   ?   D . n 
C 3 9   ILE 9   9    ?   ?   ?   D . n 
C 3 10  ALA 10  10   ?   ?   ?   D . n 
C 3 11  GLN 11  11   11  GLN GLN D . n 
C 3 12  ALA 12  12   12  ALA ALA D . n 
C 3 13  ARG 13  13   13  ARG ARG D . n 
C 3 14  LYS 14  14   14  LYS LYS D . n 
C 3 15  LEU 15  15   15  LEU LEU D . n 
C 3 16  VAL 16  16   16  VAL VAL D . n 
C 3 17  GLU 17  17   17  GLU GLU D . n 
C 3 18  GLN 18  18   18  GLN GLN D . n 
C 3 19  LEU 19  19   19  LEU LEU D . n 
C 3 20  LYS 20  20   20  LYS LYS D . n 
C 3 21  MET 21  21   21  MET MET D . n 
C 3 22  GLU 22  22   22  GLU GLU D . n 
C 3 23  ALA 23  23   23  ALA ALA D . n 
C 3 24  ASN 24  24   24  ASN ASN D . n 
C 3 25  ILE 25  25   25  ILE ILE D . n 
C 3 26  ASP 26  26   26  ASP ASP D . n 
C 3 27  ARG 27  27   27  ARG ARG D . n 
C 3 28  ILE 28  28   28  ILE ILE D . n 
C 3 29  LYS 29  29   29  LYS LYS D . n 
C 3 30  VAL 30  30   30  VAL VAL D . n 
C 3 31  SER 31  31   31  SER SER D . n 
C 3 32  LYS 32  32   32  LYS LYS D . n 
C 3 33  ALA 33  33   33  ALA ALA D . n 
C 3 34  ALA 34  34   34  ALA ALA D . n 
C 3 35  ALA 35  35   35  ALA ALA D . n 
C 3 36  ASP 36  36   36  ASP ASP D . n 
C 3 37  LEU 37  37   37  LEU LEU D . n 
C 3 38  MET 38  38   38  MET MET D . n 
C 3 39  ALA 39  39   39  ALA ALA D . n 
C 3 40  TYR 40  40   40  TYR TYR D . n 
C 3 41  CYS 41  41   41  CYS CYS D . n 
C 3 42  GLU 42  42   42  GLU GLU D . n 
C 3 43  ALA 43  43   43  ALA ALA D . n 
C 3 44  HIS 44  44   44  HIS HIS D . n 
C 3 45  ALA 45  45   45  ALA ALA D . n 
C 3 46  LYS 46  46   46  LYS LYS D . n 
C 3 47  GLU 47  47   47  GLU GLU D . n 
C 3 48  ASP 48  48   48  ASP ASP D . n 
C 3 49  PRO 49  49   49  PRO PRO D . n 
C 3 50  LEU 50  50   50  LEU LEU D . n 
C 3 51  LEU 51  51   51  LEU LEU D . n 
C 3 52  THR 52  52   52  THR THR D . n 
C 3 53  PRO 53  53   53  PRO PRO D . n 
C 3 54  VAL 54  54   54  VAL VAL D . n 
C 3 55  PRO 55  55   55  PRO PRO D . n 
C 3 56  ALA 56  56   56  ALA ALA D . n 
C 3 57  SER 57  57   57  SER SER D . n 
C 3 58  GLU 58  58   58  GLU GLU D . n 
C 3 59  ASN 59  59   59  ASN ASN D . n 
C 3 60  PRO 60  60   60  PRO PRO D . n 
C 3 61  PHE 61  61   61  PHE PHE D . n 
C 3 62  ARG 62  62   ?   ?   ?   D . n 
C 3 63  GLU 63  63   ?   ?   ?   D . n 
C 3 64  LYS 64  64   ?   ?   ?   D . n 
C 3 65  LYS 65  65   ?   ?   ?   D . n 
C 3 66  PHE 66  66   ?   ?   ?   D . n 
C 3 67  PHE 67  67   ?   ?   ?   D . n 
C 3 68  CYS 68  68   ?   ?   ?   D . n 
C 3 69  ALA 69  69   ?   ?   ?   D . n 
C 3 70  ILE 70  70   ?   ?   ?   D . n 
C 3 71  LEU 71  71   ?   ?   ?   D . n 
D 4 1   ASP 1   1    ?   ?   ?   E . n 
D 4 2   VAL 2   2    2   VAL VAL E . n 
D 4 3   GLN 3   3    3   GLN GLN E . n 
D 4 4   LEU 4   4    4   LEU LEU E . n 
D 4 5   VAL 5   5    5   VAL VAL E . n 
D 4 6   GLU 6   6    6   GLU GLU E . n 
D 4 7   SER 7   7    7   SER SER E . n 
D 4 8   GLY 8   8    8   GLY GLY E . n 
D 4 9   GLY 9   9    9   GLY GLY E . n 
D 4 10  GLY 10  10   10  GLY GLY E . n 
D 4 11  LEU 11  11   11  LEU LEU E . n 
D 4 12  VAL 12  12   12  VAL VAL E . n 
D 4 13  GLN 13  13   13  GLN GLN E . n 
D 4 14  PRO 14  14   14  PRO PRO E . n 
D 4 15  GLY 15  15   15  GLY GLY E . n 
D 4 16  GLY 16  16   16  GLY GLY E . n 
D 4 17  SER 17  17   17  SER SER E . n 
D 4 18  ARG 18  18   18  ARG ARG E . n 
D 4 19  LYS 19  19   19  LYS LYS E . n 
D 4 20  LEU 20  20   20  LEU LEU E . n 
D 4 21  SER 21  21   21  SER SER E . n 
D 4 22  CYS 22  22   22  CYS CYS E . n 
D 4 23  SER 23  23   23  SER SER E . n 
D 4 24  ALA 24  24   24  ALA ALA E . n 
D 4 25  SER 25  25   25  SER SER E . n 
D 4 26  GLY 26  26   26  GLY GLY E . n 
D 4 27  PHE 27  27   27  PHE PHE E . n 
D 4 28  ALA 28  28   28  ALA ALA E . n 
D 4 29  PHE 29  29   29  PHE PHE E . n 
D 4 30  SER 30  30   30  SER SER E . n 
D 4 31  SER 31  31   31  SER SER E . n 
D 4 32  PHE 32  32   32  PHE PHE E . n 
D 4 33  GLY 33  33   33  GLY GLY E . n 
D 4 34  MET 34  34   34  MET MET E . n 
D 4 35  HIS 35  35   35  HIS HIS E . n 
D 4 36  TRP 36  36   36  TRP TRP E . n 
D 4 37  VAL 37  37   37  VAL VAL E . n 
D 4 38  ARG 38  38   38  ARG ARG E . n 
D 4 39  GLN 39  39   39  GLN GLN E . n 
D 4 40  ALA 40  40   40  ALA ALA E . n 
D 4 41  PRO 41  41   41  PRO PRO E . n 
D 4 42  GLU 42  42   42  GLU GLU E . n 
D 4 43  LYS 43  43   43  LYS LYS E . n 
D 4 44  GLY 44  44   44  GLY GLY E . n 
D 4 45  LEU 45  45   45  LEU LEU E . n 
D 4 46  GLU 46  46   46  GLU GLU E . n 
D 4 47  TRP 47  47   47  TRP TRP E . n 
D 4 48  VAL 48  48   48  VAL VAL E . n 
D 4 49  ALA 49  49   49  ALA ALA E . n 
D 4 50  TYR 50  50   50  TYR TYR E . n 
D 4 51  ILE 51  51   51  ILE ILE E . n 
D 4 52  SER 52  52   52  SER SER E . n 
D 4 53  SER 53  53   53  SER SER E . n 
D 4 54  GLY 54  54   54  GLY GLY E . n 
D 4 55  SER 55  55   55  SER SER E . n 
D 4 56  GLY 56  56   56  GLY GLY E . n 
D 4 57  THR 57  57   57  THR THR E . n 
D 4 58  ILE 58  58   58  ILE ILE E . n 
D 4 59  TYR 59  59   59  TYR TYR E . n 
D 4 60  TYR 60  60   60  TYR TYR E . n 
D 4 61  ALA 61  61   61  ALA ALA E . n 
D 4 62  ASP 62  62   62  ASP ASP E . n 
D 4 63  THR 63  63   63  THR THR E . n 
D 4 64  VAL 64  64   64  VAL VAL E . n 
D 4 65  LYS 65  65   65  LYS LYS E . n 
D 4 66  GLY 66  66   66  GLY GLY E . n 
D 4 67  ARG 67  67   67  ARG ARG E . n 
D 4 68  PHE 68  68   68  PHE PHE E . n 
D 4 69  THR 69  69   69  THR THR E . n 
D 4 70  ILE 70  70   70  ILE ILE E . n 
D 4 71  SER 71  71   71  SER SER E . n 
D 4 72  ARG 72  72   72  ARG ARG E . n 
D 4 73  ASP 73  73   73  ASP ASP E . n 
D 4 74  ASP 74  74   74  ASP ASP E . n 
D 4 75  PRO 75  75   75  PRO PRO E . n 
D 4 76  LYS 76  76   76  LYS LYS E . n 
D 4 77  ASN 77  77   77  ASN ASN E . n 
D 4 78  THR 78  78   78  THR THR E . n 
D 4 79  LEU 79  79   79  LEU LEU E . n 
D 4 80  PHE 80  80   80  PHE PHE E . n 
D 4 81  LEU 81  81   81  LEU LEU E . n 
D 4 82  GLN 82  82   82  GLN GLN E . n 
D 4 83  MET 83  83   83  MET MET E . n 
D 4 84  THR 84  84   84  THR THR E . n 
D 4 85  SER 85  85   85  SER SER E . n 
D 4 86  LEU 86  86   86  LEU LEU E . n 
D 4 87  ARG 87  87   87  ARG ARG E . n 
D 4 88  SER 88  88   88  SER SER E . n 
D 4 89  GLU 89  89   89  GLU GLU E . n 
D 4 90  ASP 90  90   90  ASP ASP E . n 
D 4 91  THR 91  91   91  THR THR E . n 
D 4 92  ALA 92  92   92  ALA ALA E . n 
D 4 93  MET 93  93   93  MET MET E . n 
D 4 94  TYR 94  94   94  TYR TYR E . n 
D 4 95  TYR 95  95   95  TYR TYR E . n 
D 4 96  CYS 96  96   96  CYS CYS E . n 
D 4 97  VAL 97  97   97  VAL VAL E . n 
D 4 98  ARG 98  98   98  ARG ARG E . n 
D 4 99  SER 99  99   99  SER SER E . n 
D 4 100 ILE 100 100  100 ILE ILE E . n 
D 4 101 TYR 101 101  101 TYR TYR E . n 
D 4 102 TYR 102 102  102 TYR TYR E . n 
D 4 103 TYR 103 103  103 TYR TYR E . n 
D 4 104 GLY 104 104  104 GLY GLY E . n 
D 4 105 SER 105 105  105 SER SER E . n 
D 4 106 SER 106 106  106 SER SER E . n 
D 4 107 PRO 107 107  107 PRO PRO E . n 
D 4 108 PHE 108 108  108 PHE PHE E . n 
D 4 109 ASP 109 109  109 ASP ASP E . n 
D 4 110 PHE 110 110  110 PHE PHE E . n 
D 4 111 TRP 111 111  111 TRP TRP E . n 
D 4 112 GLY 112 112  112 GLY GLY E . n 
D 4 113 GLN 113 113  113 GLN GLN E . n 
D 4 114 GLY 114 114  114 GLY GLY E . n 
D 4 115 THR 115 115  115 THR THR E . n 
D 4 116 THR 116 116  116 THR THR E . n 
D 4 117 LEU 117 117  117 LEU LEU E . n 
D 4 118 THR 118 118  118 THR THR E . n 
D 4 119 VAL 119 119  119 VAL VAL E . n 
D 4 120 SER 120 120  120 SER SER E . n 
D 4 121 SER 121 120  ?   ?   ?   E A n 
D 4 122 GLY 122 120  ?   ?   ?   E B n 
D 4 123 GLY 123 120  ?   ?   ?   E C n 
D 4 124 GLY 124 120  ?   ?   ?   E D n 
D 4 125 GLY 125 120  ?   ?   ?   E E n 
D 4 126 SER 126 120  ?   ?   ?   E F n 
D 4 127 GLY 127 120  ?   ?   ?   E G n 
D 4 128 GLY 128 120  ?   ?   ?   E H n 
D 4 129 GLY 129 120  ?   ?   ?   E I n 
D 4 130 GLY 130 120  ?   ?   ?   E J n 
D 4 131 SER 131 120  ?   ?   ?   E K n 
D 4 132 GLY 132 120  ?   ?   ?   E L n 
D 4 133 GLY 133 120  ?   ?   ?   E M n 
D 4 134 GLY 134 120  ?   ?   ?   E N n 
D 4 135 GLY 135 120  ?   ?   ?   E O n 
D 4 136 SER 136 124  124 SER SER E . n 
D 4 137 ASP 137 125  125 ASP ASP E . n 
D 4 138 ILE 138 126  126 ILE ILE E . n 
D 4 139 VAL 139 127  127 VAL VAL E . n 
D 4 140 MET 140 128  128 MET MET E . n 
D 4 141 THR 141 129  129 THR THR E . n 
D 4 142 GLN 142 130  130 GLN GLN E . n 
D 4 143 ALA 143 131  131 ALA ALA E . n 
D 4 144 THR 144 132  132 THR THR E . n 
D 4 145 SER 145 133  133 SER SER E . n 
D 4 146 SER 146 134  134 SER SER E . n 
D 4 147 VAL 147 135  135 VAL VAL E . n 
D 4 148 PRO 148 136  136 PRO PRO E . n 
D 4 149 VAL 149 137  137 VAL VAL E . n 
D 4 150 THR 150 138  138 THR THR E . n 
D 4 151 PRO 151 139  139 PRO PRO E . n 
D 4 152 GLY 152 140  140 GLY GLY E . n 
D 4 153 GLU 153 141  141 GLU GLU E . n 
D 4 154 SER 154 142  142 SER SER E . n 
D 4 155 VAL 155 143  143 VAL VAL E . n 
D 4 156 SER 156 144  144 SER SER E . n 
D 4 157 ILE 157 145  145 ILE ILE E . n 
D 4 158 SER 158 146  146 SER SER E . n 
D 4 159 CYS 159 147  147 CYS CYS E . n 
D 4 160 ARG 160 148  148 ARG ARG E . n 
D 4 161 SER 161 149  149 SER SER E . n 
D 4 162 SER 162 150  150 SER SER E . n 
D 4 163 LYS 163 151  151 LYS LYS E . n 
D 4 164 SER 164 152  152 SER SER E . n 
D 4 165 LEU 165 153  153 LEU LEU E . n 
D 4 166 LEU 166 154  154 LEU LEU E . n 
D 4 167 HIS 167 155  155 HIS HIS E . n 
D 4 168 SER 168 156  156 SER SER E . n 
D 4 169 ASN 169 157  157 ASN ASN E . n 
D 4 170 GLY 170 158  158 GLY GLY E . n 
D 4 171 ASN 171 159  159 ASN ASN E . n 
D 4 172 THR 172 160  160 THR THR E . n 
D 4 173 TYR 173 161  161 TYR TYR E . n 
D 4 174 LEU 174 162  162 LEU LEU E . n 
D 4 175 TYR 175 163  163 TYR TYR E . n 
D 4 176 TRP 176 164  164 TRP TRP E . n 
D 4 177 PHE 177 165  165 PHE PHE E . n 
D 4 178 LEU 178 166  166 LEU LEU E . n 
D 4 179 GLN 179 167  167 GLN GLN E . n 
D 4 180 ARG 180 168  168 ARG ARG E . n 
D 4 181 PRO 181 169  169 PRO PRO E . n 
D 4 182 GLY 182 170  170 GLY GLY E . n 
D 4 183 GLN 183 171  171 GLN GLN E . n 
D 4 184 SER 184 172  172 SER SER E . n 
D 4 185 PRO 185 173  173 PRO PRO E . n 
D 4 186 GLN 186 174  174 GLN GLN E . n 
D 4 187 LEU 187 175  175 LEU LEU E . n 
D 4 188 LEU 188 176  176 LEU LEU E . n 
D 4 189 ILE 189 177  177 ILE ILE E . n 
D 4 190 TYR 190 178  178 TYR TYR E . n 
D 4 191 ARG 191 179  179 ARG ARG E . n 
D 4 192 MET 192 180  180 MET MET E . n 
D 4 193 SER 193 181  181 SER SER E . n 
D 4 194 ASN 194 182  182 ASN ASN E . n 
D 4 195 LEU 195 183  183 LEU LEU E . n 
D 4 196 ALA 196 184  184 ALA ALA E . n 
D 4 197 SER 197 185  185 SER SER E . n 
D 4 198 GLY 198 186  186 GLY GLY E . n 
D 4 199 VAL 199 187  187 VAL VAL E . n 
D 4 200 PRO 200 188  188 PRO PRO E . n 
D 4 201 ASP 201 189  189 ASP ASP E . n 
D 4 202 ARG 202 190  190 ARG ARG E . n 
D 4 203 PHE 203 191  191 PHE PHE E . n 
D 4 204 SER 204 192  192 SER SER E . n 
D 4 205 GLY 205 193  193 GLY GLY E . n 
D 4 206 SER 206 194  194 SER SER E . n 
D 4 207 GLY 207 195  195 GLY GLY E . n 
D 4 208 SER 208 196  196 SER SER E . n 
D 4 209 GLY 209 197  197 GLY GLY E . n 
D 4 210 THR 210 198  198 THR THR E . n 
D 4 211 ALA 211 199  199 ALA ALA E . n 
D 4 212 PHE 212 200  200 PHE PHE E . n 
D 4 213 THR 213 201  201 THR THR E . n 
D 4 214 LEU 214 202  202 LEU LEU E . n 
D 4 215 THR 215 203  203 THR THR E . n 
D 4 216 ILE 216 204  204 ILE ILE E . n 
D 4 217 SER 217 205  205 SER SER E . n 
D 4 218 ARG 218 206  206 ARG ARG E . n 
D 4 219 LEU 219 207  207 LEU LEU E . n 
D 4 220 GLU 220 208  208 GLU GLU E . n 
D 4 221 ALA 221 209  209 ALA ALA E . n 
D 4 222 GLU 222 210  210 GLU GLU E . n 
D 4 223 ASP 223 211  211 ASP ASP E . n 
D 4 224 VAL 224 212  212 VAL VAL E . n 
D 4 225 GLY 225 213  213 GLY GLY E . n 
D 4 226 VAL 226 214  214 VAL VAL E . n 
D 4 227 TYR 227 215  215 TYR TYR E . n 
D 4 228 TYR 228 216  216 TYR TYR E . n 
D 4 229 CYS 229 217  217 CYS CYS E . n 
D 4 230 MET 230 218  218 MET MET E . n 
D 4 231 GLN 231 219  219 GLN GLN E . n 
D 4 232 HIS 232 220  220 HIS HIS E . n 
D 4 233 LEU 233 221  221 LEU LEU E . n 
D 4 234 GLU 234 222  222 GLU GLU E . n 
D 4 235 TYR 235 223  223 TYR TYR E . n 
D 4 236 PRO 236 224  224 PRO PRO E . n 
D 4 237 LEU 237 225  225 LEU LEU E . n 
D 4 238 THR 238 226  226 THR THR E . n 
D 4 239 PHE 239 227  227 PHE PHE E . n 
D 4 240 GLY 240 228  228 GLY GLY E . n 
D 4 241 ALA 241 229  229 ALA ALA E . n 
D 4 242 GLY 242 230  230 GLY GLY E . n 
D 4 243 THR 243 231  231 THR THR E . n 
D 4 244 LYS 244 232  232 LYS LYS E . n 
D 4 245 LEU 245 233  233 LEU LEU E . n 
D 4 246 GLU 246 234  234 GLU GLU E . n 
D 4 247 LEU 247 235  235 LEU LEU E . n 
D 4 248 LYS 248 236  ?   ?   ?   E . n 
D 4 249 ALA 249 237  ?   ?   ?   E . n 
D 4 250 ALA 250 238  ?   ?   ?   E . n 
D 4 251 ALA 251 239  ?   ?   ?   E . n 
D 4 252 LEU 252 240  ?   ?   ?   E . n 
D 4 253 GLU 253 241  ?   ?   ?   E . n 
D 4 254 VAL 254 242  ?   ?   ?   E . n 
D 4 255 LEU 255 243  ?   ?   ?   E . n 
D 4 256 PHE 256 244  ?   ?   ?   E . n 
D 4 257 GLN 257 245  ?   ?   ?   E . n 
D 4 258 GLY 258 246  ?   ?   ?   E . n 
D 4 259 PRO 259 247  ?   ?   ?   E . n 
D 4 260 HIS 260 248  ?   ?   ?   E . n 
D 4 261 HIS 261 249  ?   ?   ?   E . n 
D 4 262 HIS 262 250  ?   ?   ?   E . n 
D 4 263 HIS 263 251  ?   ?   ?   E . n 
D 4 264 HIS 264 252  ?   ?   ?   E . n 
D 4 265 HIS 265 253  ?   ?   ?   E . n 
D 4 266 HIS 266 254  ?   ?   ?   E . n 
D 4 267 HIS 267 255  ?   ?   ?   E . n 
E 5 1   ASP 1   -149 ?   ?   ?   R . n 
E 5 2   TYR 2   -148 ?   ?   ?   R . n 
E 5 3   LYS 3   -147 ?   ?   ?   R . n 
E 5 4   ASP 4   -146 ?   ?   ?   R . n 
E 5 5   ASP 5   -145 ?   ?   ?   R . n 
E 5 6   ASP 6   -144 ?   ?   ?   R . n 
E 5 7   ASP 7   -143 ?   ?   ?   R . n 
E 5 8   ALA 8   -142 ?   ?   ?   R . n 
E 5 9   LYS 9   -141 ?   ?   ?   R . n 
E 5 10  LEU 10  -140 ?   ?   ?   R . n 
E 5 11  GLN 11  -139 ?   ?   ?   R . n 
E 5 12  THR 12  -138 ?   ?   ?   R . n 
E 5 13  MET 13  -137 ?   ?   ?   R . n 
E 5 14  HIS 14  -136 ?   ?   ?   R . n 
E 5 15  HIS 15  -135 ?   ?   ?   R . n 
E 5 16  HIS 16  -134 ?   ?   ?   R . n 
E 5 17  HIS 17  -133 ?   ?   ?   R . n 
E 5 18  HIS 18  -132 ?   ?   ?   R . n 
E 5 19  HIS 19  -131 ?   ?   ?   R . n 
E 5 20  HIS 20  -130 ?   ?   ?   R . n 
E 5 21  HIS 21  -129 ?   ?   ?   R . n 
E 5 22  HIS 22  -128 ?   ?   ?   R . n 
E 5 23  HIS 23  -127 ?   ?   ?   R . n 
E 5 24  GLU 24  -126 ?   ?   ?   R . n 
E 5 25  ASN 25  -125 ?   ?   ?   R . n 
E 5 26  LEU 26  -124 ?   ?   ?   R . n 
E 5 27  TYR 27  -123 ?   ?   ?   R . n 
E 5 28  PHE 28  -122 ?   ?   ?   R . n 
E 5 29  GLN 29  -121 ?   ?   ?   R . n 
E 5 30  GLY 30  -120 ?   ?   ?   R . n 
E 5 31  GLY 31  -119 ?   ?   ?   R . n 
E 5 32  THR 32  -118 ?   ?   ?   R . n 
E 5 33  THR 33  -117 ?   ?   ?   R . n 
E 5 34  MET 34  -116 ?   ?   ?   R . n 
E 5 35  ALA 35  -115 ?   ?   ?   R . n 
E 5 36  ASP 36  -114 ?   ?   ?   R . n 
E 5 37  LEU 37  -113 ?   ?   ?   R . n 
E 5 38  GLU 38  -112 ?   ?   ?   R . n 
E 5 39  ASP 39  -111 ?   ?   ?   R . n 
E 5 40  ASN 40  -110 ?   ?   ?   R . n 
E 5 41  TRP 41  -109 ?   ?   ?   R . n 
E 5 42  GLU 42  -108 ?   ?   ?   R . n 
E 5 43  THR 43  -107 ?   ?   ?   R . n 
E 5 44  LEU 44  -106 ?   ?   ?   R . n 
E 5 45  ASN 45  -105 ?   ?   ?   R . n 
E 5 46  ASP 46  -104 ?   ?   ?   R . n 
E 5 47  ASN 47  -103 ?   ?   ?   R . n 
E 5 48  LEU 48  -102 ?   ?   ?   R . n 
E 5 49  LYS 49  -101 ?   ?   ?   R . n 
E 5 50  VAL 50  -100 ?   ?   ?   R . n 
E 5 51  ILE 51  -99  ?   ?   ?   R . n 
E 5 52  GLU 52  -98  ?   ?   ?   R . n 
E 5 53  LYS 53  -97  ?   ?   ?   R . n 
E 5 54  ALA 54  -96  ?   ?   ?   R . n 
E 5 55  ASP 55  -95  ?   ?   ?   R . n 
E 5 56  ASN 56  -94  ?   ?   ?   R . n 
E 5 57  ALA 57  -93  ?   ?   ?   R . n 
E 5 58  ALA 58  -92  ?   ?   ?   R . n 
E 5 59  GLN 59  -91  ?   ?   ?   R . n 
E 5 60  VAL 60  -90  ?   ?   ?   R . n 
E 5 61  LYS 61  -89  ?   ?   ?   R . n 
E 5 62  ASP 62  -88  ?   ?   ?   R . n 
E 5 63  ALA 63  -87  ?   ?   ?   R . n 
E 5 64  LEU 64  -86  ?   ?   ?   R . n 
E 5 65  THR 65  -85  ?   ?   ?   R . n 
E 5 66  LYS 66  -84  ?   ?   ?   R . n 
E 5 67  MET 67  -83  ?   ?   ?   R . n 
E 5 68  ARG 68  -82  ?   ?   ?   R . n 
E 5 69  ALA 69  -81  ?   ?   ?   R . n 
E 5 70  ALA 70  -80  ?   ?   ?   R . n 
E 5 71  ALA 71  -79  ?   ?   ?   R . n 
E 5 72  LEU 72  -78  ?   ?   ?   R . n 
E 5 73  ASP 73  -77  ?   ?   ?   R . n 
E 5 74  ALA 74  -76  ?   ?   ?   R . n 
E 5 75  GLN 75  -75  ?   ?   ?   R . n 
E 5 76  LYS 76  -74  ?   ?   ?   R . n 
E 5 77  ALA 77  -73  ?   ?   ?   R . n 
E 5 78  THR 78  -72  ?   ?   ?   R . n 
E 5 79  PRO 79  -71  ?   ?   ?   R . n 
E 5 80  PRO 80  -70  ?   ?   ?   R . n 
E 5 81  LYS 81  -69  ?   ?   ?   R . n 
E 5 82  LEU 82  -68  ?   ?   ?   R . n 
E 5 83  GLU 83  -67  ?   ?   ?   R . n 
E 5 84  ASP 84  -66  ?   ?   ?   R . n 
E 5 85  LYS 85  -65  ?   ?   ?   R . n 
E 5 86  SER 86  -64  ?   ?   ?   R . n 
E 5 87  PRO 87  -63  ?   ?   ?   R . n 
E 5 88  ASP 88  -62  ?   ?   ?   R . n 
E 5 89  SER 89  -61  ?   ?   ?   R . n 
E 5 90  PRO 90  -60  ?   ?   ?   R . n 
E 5 91  GLU 91  -59  ?   ?   ?   R . n 
E 5 92  MET 92  -58  ?   ?   ?   R . n 
E 5 93  LYS 93  -57  ?   ?   ?   R . n 
E 5 94  ASP 94  -56  ?   ?   ?   R . n 
E 5 95  PHE 95  -55  ?   ?   ?   R . n 
E 5 96  ARG 96  -54  ?   ?   ?   R . n 
E 5 97  HIS 97  -53  ?   ?   ?   R . n 
E 5 98  GLY 98  -52  ?   ?   ?   R . n 
E 5 99  PHE 99  -51  ?   ?   ?   R . n 
E 5 100 ASP 100 -50  ?   ?   ?   R . n 
E 5 101 ILE 101 -49  ?   ?   ?   R . n 
E 5 102 LEU 102 -48  ?   ?   ?   R . n 
E 5 103 VAL 103 -47  ?   ?   ?   R . n 
E 5 104 GLY 104 -46  ?   ?   ?   R . n 
E 5 105 GLN 105 -45  ?   ?   ?   R . n 
E 5 106 ILE 106 -44  ?   ?   ?   R . n 
E 5 107 ASP 107 -43  ?   ?   ?   R . n 
E 5 108 ASP 108 -42  ?   ?   ?   R . n 
E 5 109 ALA 109 -41  ?   ?   ?   R . n 
E 5 110 LEU 110 -40  ?   ?   ?   R . n 
E 5 111 LYS 111 -39  ?   ?   ?   R . n 
E 5 112 LEU 112 -38  ?   ?   ?   R . n 
E 5 113 ALA 113 -37  ?   ?   ?   R . n 
E 5 114 ASN 114 -36  ?   ?   ?   R . n 
E 5 115 GLU 115 -35  ?   ?   ?   R . n 
E 5 116 GLY 116 -34  ?   ?   ?   R . n 
E 5 117 LYS 117 -33  ?   ?   ?   R . n 
E 5 118 VAL 118 -32  ?   ?   ?   R . n 
E 5 119 LYS 119 -31  ?   ?   ?   R . n 
E 5 120 GLU 120 -30  ?   ?   ?   R . n 
E 5 121 ALA 121 -29  ?   ?   ?   R . n 
E 5 122 GLN 122 -28  ?   ?   ?   R . n 
E 5 123 ALA 123 -27  ?   ?   ?   R . n 
E 5 124 ALA 124 -26  ?   ?   ?   R . n 
E 5 125 ALA 125 -25  ?   ?   ?   R . n 
E 5 126 GLU 126 -24  ?   ?   ?   R . n 
E 5 127 GLN 127 -23  ?   ?   ?   R . n 
E 5 128 LEU 128 -22  ?   ?   ?   R . n 
E 5 129 LYS 129 -21  ?   ?   ?   R . n 
E 5 130 THR 130 -20  ?   ?   ?   R . n 
E 5 131 THR 131 -19  ?   ?   ?   R . n 
E 5 132 ARG 132 -18  ?   ?   ?   R . n 
E 5 133 ASN 133 -17  ?   ?   ?   R . n 
E 5 134 ALA 134 -16  ?   ?   ?   R . n 
E 5 135 TYR 135 -15  ?   ?   ?   R . n 
E 5 136 ILE 136 -14  ?   ?   ?   R . n 
E 5 137 GLN 137 -13  ?   ?   ?   R . n 
E 5 138 LYS 138 -12  ?   ?   ?   R . n 
E 5 139 TYR 139 -11  ?   ?   ?   R . n 
E 5 140 LEU 140 -10  ?   ?   ?   R . n 
E 5 141 GLY 141 -9   ?   ?   ?   R . n 
E 5 142 SER 142 -8   ?   ?   ?   R . n 
E 5 143 THR 143 -7   ?   ?   ?   R . n 
E 5 144 LEU 144 -6   ?   ?   ?   R . n 
E 5 145 GLU 145 -5   ?   ?   ?   R . n 
E 5 146 VAL 146 -4   ?   ?   ?   R . n 
E 5 147 LEU 147 -3   ?   ?   ?   R . n 
E 5 148 PHE 148 -2   ?   ?   ?   R . n 
E 5 149 GLN 149 -1   ?   ?   ?   R . n 
E 5 150 GLY 150 0    ?   ?   ?   R . n 
E 5 151 PRO 151 1    ?   ?   ?   R . n 
E 5 152 ASP 152 2    ?   ?   ?   R . n 
E 5 153 PRO 153 3    ?   ?   ?   R . n 
E 5 154 THR 154 4    ?   ?   ?   R . n 
E 5 155 VAL 155 5    ?   ?   ?   R . n 
E 5 156 PRO 156 6    ?   ?   ?   R . n 
E 5 157 VAL 157 7    ?   ?   ?   R . n 
E 5 158 PHE 158 8    ?   ?   ?   R . n 
E 5 159 GLY 159 9    ?   ?   ?   R . n 
E 5 160 THR 160 10   ?   ?   ?   R . n 
E 5 161 LYS 161 11   ?   ?   ?   R . n 
E 5 162 LEU 162 12   ?   ?   ?   R . n 
E 5 163 THR 163 13   ?   ?   ?   R . n 
E 5 164 PRO 164 14   ?   ?   ?   R . n 
E 5 165 ILE 165 15   ?   ?   ?   R . n 
E 5 166 ASN 166 16   ?   ?   ?   R . n 
E 5 167 GLY 167 17   ?   ?   ?   R . n 
E 5 168 ARG 168 18   ?   ?   ?   R . n 
E 5 169 GLU 169 19   ?   ?   ?   R . n 
E 5 170 GLU 170 20   ?   ?   ?   R . n 
E 5 171 THR 171 21   ?   ?   ?   R . n 
E 5 172 PRO 172 22   ?   ?   ?   R . n 
E 5 173 CYS 173 23   ?   ?   ?   R . n 
E 5 174 TYR 174 24   ?   ?   ?   R . n 
E 5 175 ASN 175 25   ?   ?   ?   R . n 
E 5 176 GLN 176 26   26  GLN GLN R . n 
E 5 177 THR 177 27   27  THR THR R . n 
E 5 178 LEU 178 28   28  LEU LEU R . n 
E 5 179 SER 179 29   29  SER SER R . n 
E 5 180 PHE 180 30   30  PHE PHE R . n 
E 5 181 THR 181 31   31  THR THR R . n 
E 5 182 VAL 182 32   32  VAL VAL R . n 
E 5 183 LEU 183 33   33  LEU LEU R . n 
E 5 184 THR 184 34   34  THR THR R . n 
E 5 185 CYS 185 35   35  CYS CYS R . n 
E 5 186 ILE 186 36   36  ILE ILE R . n 
E 5 187 ILE 187 37   37  ILE ILE R . n 
E 5 188 SER 188 38   38  SER SER R . n 
E 5 189 LEU 189 39   39  LEU LEU R . n 
E 5 190 VAL 190 40   40  VAL VAL R . n 
E 5 191 GLY 191 41   41  GLY GLY R . n 
E 5 192 LEU 192 42   42  LEU LEU R . n 
E 5 193 THR 193 43   43  THR THR R . n 
E 5 194 GLY 194 44   44  GLY GLY R . n 
E 5 195 ASN 195 45   45  ASN ASN R . n 
E 5 196 ALA 196 46   46  ALA ALA R . n 
E 5 197 VAL 197 47   47  VAL VAL R . n 
E 5 198 VAL 198 48   48  VAL VAL R . n 
E 5 199 LEU 199 49   49  LEU LEU R . n 
E 5 200 TRP 200 50   50  TRP TRP R . n 
E 5 201 LEU 201 51   51  LEU LEU R . n 
E 5 202 LEU 202 52   52  LEU LEU R . n 
E 5 203 GLY 203 53   53  GLY GLY R . n 
E 5 204 TYR 204 54   54  TYR TYR R . n 
E 5 205 ARG 205 55   55  ARG ARG R . n 
E 5 206 MET 206 56   56  MET MET R . n 
E 5 207 ARG 207 57   57  ARG ARG R . n 
E 5 208 ARG 208 58   58  ARG ARG R . n 
E 5 209 ASN 209 59   59  ASN ASN R . n 
E 5 210 ALA 210 60   60  ALA ALA R . n 
E 5 211 VAL 211 61   61  VAL VAL R . n 
E 5 212 SER 212 62   62  SER SER R . n 
E 5 213 ILE 213 63   63  ILE ILE R . n 
E 5 214 TYR 214 64   64  TYR TYR R . n 
E 5 215 ILE 215 65   65  ILE ILE R . n 
E 5 216 LEU 216 66   66  LEU LEU R . n 
E 5 217 ASN 217 67   67  ASN ASN R . n 
E 5 218 LEU 218 68   68  LEU LEU R . n 
E 5 219 ALA 219 69   69  ALA ALA R . n 
E 5 220 ALA 220 70   70  ALA ALA R . n 
E 5 221 ALA 221 71   71  ALA ALA R . n 
E 5 222 ASP 222 72   72  ASP ASP R . n 
E 5 223 PHE 223 73   73  PHE PHE R . n 
E 5 224 LEU 224 74   74  LEU LEU R . n 
E 5 225 PHE 225 75   75  PHE PHE R . n 
E 5 226 LEU 226 76   76  LEU LEU R . n 
E 5 227 SER 227 77   77  SER SER R . n 
E 5 228 PHE 228 78   78  PHE PHE R . n 
E 5 229 GLN 229 79   79  GLN GLN R . n 
E 5 230 ILE 230 80   80  ILE ILE R . n 
E 5 231 ILE 231 81   81  ILE ILE R . n 
E 5 232 ARG 232 82   82  ARG ARG R . n 
E 5 233 SER 233 83   83  SER SER R . n 
E 5 234 PRO 234 84   84  PRO PRO R . n 
E 5 235 LEU 235 85   85  LEU LEU R . n 
E 5 236 ARG 236 86   86  ARG ARG R . n 
E 5 237 LEU 237 87   87  LEU LEU R . n 
E 5 238 ILE 238 88   88  ILE ILE R . n 
E 5 239 ASN 239 89   89  ASN ASN R . n 
E 5 240 ILE 240 90   90  ILE ILE R . n 
E 5 241 SER 241 91   91  SER SER R . n 
E 5 242 HIS 242 92   92  HIS HIS R . n 
E 5 243 LEU 243 93   93  LEU LEU R . n 
E 5 244 ILE 244 94   94  ILE ILE R . n 
E 5 245 ARG 245 95   95  ARG ARG R . n 
E 5 246 LYS 246 96   96  LYS LYS R . n 
E 5 247 ILE 247 97   97  ILE ILE R . n 
E 5 248 LEU 248 98   98  LEU LEU R . n 
E 5 249 VAL 249 99   99  VAL VAL R . n 
E 5 250 SER 250 100  100 SER SER R . n 
E 5 251 VAL 251 101  101 VAL VAL R . n 
E 5 252 MET 252 102  102 MET MET R . n 
E 5 253 THR 253 103  103 THR THR R . n 
E 5 254 PHE 254 104  104 PHE PHE R . n 
E 5 255 PRO 255 105  105 PRO PRO R . n 
E 5 256 TYR 256 106  106 TYR TYR R . n 
E 5 257 PHE 257 107  107 PHE PHE R . n 
E 5 258 THR 258 108  108 THR THR R . n 
E 5 259 GLY 259 109  109 GLY GLY R . n 
E 5 260 LEU 260 110  110 LEU LEU R . n 
E 5 261 SER 261 111  111 SER SER R . n 
E 5 262 MET 262 112  112 MET MET R . n 
E 5 263 LEU 263 113  113 LEU LEU R . n 
E 5 264 SER 264 114  114 SER SER R . n 
E 5 265 ALA 265 115  115 ALA ALA R . n 
E 5 266 ILE 266 116  116 ILE ILE R . n 
E 5 267 SER 267 117  117 SER SER R . n 
E 5 268 THR 268 118  118 THR THR R . n 
E 5 269 GLU 269 119  119 GLU GLU R . n 
E 5 270 ARG 270 120  120 ARG ARG R . n 
E 5 271 CYS 271 121  121 CYS CYS R . n 
E 5 272 LEU 272 122  122 LEU LEU R . n 
E 5 273 SER 273 123  123 SER SER R . n 
E 5 274 VAL 274 124  124 VAL VAL R . n 
E 5 275 LEU 275 125  125 LEU LEU R . n 
E 5 276 TRP 276 126  126 TRP TRP R . n 
E 5 277 PRO 277 127  127 PRO PRO R . n 
E 5 278 ILE 278 128  128 ILE ILE R . n 
E 5 279 TRP 279 129  129 TRP TRP R . n 
E 5 280 TYR 280 130  130 TYR TYR R . n 
E 5 281 ARG 281 131  131 ARG ARG R . n 
E 5 282 CYS 282 132  132 CYS CYS R . n 
E 5 283 ARG 283 133  133 ARG ARG R . n 
E 5 284 ARG 284 134  134 ARG ARG R . n 
E 5 285 PRO 285 135  135 PRO PRO R . n 
E 5 286 THR 286 136  136 THR THR R . n 
E 5 287 HIS 287 137  137 HIS HIS R . n 
E 5 288 LEU 288 138  138 LEU LEU R . n 
E 5 289 SER 289 139  139 SER SER R . n 
E 5 290 ALA 290 140  140 ALA ALA R . n 
E 5 291 VAL 291 141  141 VAL VAL R . n 
E 5 292 VAL 292 142  142 VAL VAL R . n 
E 5 293 CYS 293 143  143 CYS CYS R . n 
E 5 294 VAL 294 144  144 VAL VAL R . n 
E 5 295 LEU 295 145  145 LEU LEU R . n 
E 5 296 LEU 296 146  146 LEU LEU R . n 
E 5 297 TRP 297 147  147 TRP TRP R . n 
E 5 298 GLY 298 148  148 GLY GLY R . n 
E 5 299 LEU 299 149  149 LEU LEU R . n 
E 5 300 SER 300 150  150 SER SER R . n 
E 5 301 LEU 301 151  151 LEU LEU R . n 
E 5 302 LEU 302 152  152 LEU LEU R . n 
E 5 303 PHE 303 153  153 PHE PHE R . n 
E 5 304 SER 304 154  154 SER SER R . n 
E 5 305 MET 305 155  155 MET MET R . n 
E 5 306 LEU 306 156  156 LEU LEU R . n 
E 5 307 GLU 307 157  157 GLU GLU R . n 
E 5 308 TRP 308 158  158 TRP TRP R . n 
E 5 309 ARG 309 159  159 ARG ARG R . n 
E 5 310 PHE 310 160  160 PHE PHE R . n 
E 5 311 CYS 311 161  ?   ?   ?   R . n 
E 5 312 ASP 312 162  ?   ?   ?   R . n 
E 5 313 PHE 313 163  ?   ?   ?   R . n 
E 5 314 LEU 314 164  ?   ?   ?   R . n 
E 5 315 PHE 315 165  ?   ?   ?   R . n 
E 5 316 SER 316 166  ?   ?   ?   R . n 
E 5 317 GLY 317 167  ?   ?   ?   R . n 
E 5 318 ALA 318 168  ?   ?   ?   R . n 
E 5 319 ASP 319 169  ?   ?   ?   R . n 
E 5 320 SER 320 170  ?   ?   ?   R . n 
E 5 321 SER 321 171  ?   ?   ?   R . n 
E 5 322 TRP 322 172  ?   ?   ?   R . n 
E 5 323 CYS 323 173  ?   ?   ?   R . n 
E 5 324 GLU 324 174  ?   ?   ?   R . n 
E 5 325 THR 325 175  175 THR THR R . n 
E 5 326 SER 326 176  176 SER SER R . n 
E 5 327 ASP 327 177  177 ASP ASP R . n 
E 5 328 PHE 328 178  178 PHE PHE R . n 
E 5 329 ILE 329 179  179 ILE ILE R . n 
E 5 330 PRO 330 180  180 PRO PRO R . n 
E 5 331 VAL 331 181  181 VAL VAL R . n 
E 5 332 ALA 332 182  182 ALA ALA R . n 
E 5 333 TRP 333 183  183 TRP TRP R . n 
E 5 334 LEU 334 184  184 LEU LEU R . n 
E 5 335 ILE 335 185  185 ILE ILE R . n 
E 5 336 PHE 336 186  186 PHE PHE R . n 
E 5 337 LEU 337 187  187 LEU LEU R . n 
E 5 338 CYS 338 188  188 CYS CYS R . n 
E 5 339 VAL 339 189  189 VAL VAL R . n 
E 5 340 VAL 340 190  190 VAL VAL R . n 
E 5 341 LEU 341 191  191 LEU LEU R . n 
E 5 342 CYS 342 192  192 CYS CYS R . n 
E 5 343 VAL 343 193  193 VAL VAL R . n 
E 5 344 SER 344 194  194 SER SER R . n 
E 5 345 SER 345 195  195 SER SER R . n 
E 5 346 LEU 346 196  196 LEU LEU R . n 
E 5 347 VAL 347 197  197 VAL VAL R . n 
E 5 348 LEU 348 198  198 LEU LEU R . n 
E 5 349 LEU 349 199  199 LEU LEU R . n 
E 5 350 VAL 350 200  200 VAL VAL R . n 
E 5 351 ARG 351 201  201 ARG ARG R . n 
E 5 352 ILE 352 202  202 ILE ILE R . n 
E 5 353 LEU 353 203  203 LEU LEU R . n 
E 5 354 CYS 354 204  204 CYS CYS R . n 
E 5 355 GLY 355 205  205 GLY GLY R . n 
E 5 356 SER 356 206  206 SER SER R . n 
E 5 357 ARG 357 207  207 ARG ARG R . n 
E 5 358 LYS 358 208  208 LYS LYS R . n 
E 5 359 MET 359 209  209 MET MET R . n 
E 5 360 PRO 360 210  210 PRO PRO R . n 
E 5 361 LEU 361 211  211 LEU LEU R . n 
E 5 362 THR 362 212  212 THR THR R . n 
E 5 363 ARG 363 213  213 ARG ARG R . n 
E 5 364 LEU 364 214  214 LEU LEU R . n 
E 5 365 TYR 365 215  215 TYR TYR R . n 
E 5 366 VAL 366 216  216 VAL VAL R . n 
E 5 367 THR 367 217  217 THR THR R . n 
E 5 368 ILE 368 218  218 ILE ILE R . n 
E 5 369 LEU 369 219  219 LEU LEU R . n 
E 5 370 LEU 370 220  220 LEU LEU R . n 
E 5 371 THR 371 221  221 THR THR R . n 
E 5 372 VAL 372 222  222 VAL VAL R . n 
E 5 373 LEU 373 223  223 LEU LEU R . n 
E 5 374 VAL 374 224  224 VAL VAL R . n 
E 5 375 PHE 375 225  225 PHE PHE R . n 
E 5 376 LEU 376 226  226 LEU LEU R . n 
E 5 377 LEU 377 227  227 LEU LEU R . n 
E 5 378 CYS 378 228  228 CYS CYS R . n 
E 5 379 GLY 379 229  229 GLY GLY R . n 
E 5 380 LEU 380 230  230 LEU LEU R . n 
E 5 381 PRO 381 231  231 PRO PRO R . n 
E 5 382 PHE 382 232  232 PHE PHE R . n 
E 5 383 GLY 383 233  233 GLY GLY R . n 
E 5 384 ILE 384 234  234 ILE ILE R . n 
E 5 385 LEU 385 235  235 LEU LEU R . n 
E 5 386 GLY 386 236  236 GLY GLY R . n 
E 5 387 ALA 387 237  237 ALA ALA R . n 
E 5 388 LEU 388 238  238 LEU LEU R . n 
E 5 389 ILE 389 239  239 ILE ILE R . n 
E 5 390 TYR 390 240  240 TYR TYR R . n 
E 5 391 ARG 391 241  241 ARG ARG R . n 
E 5 392 MET 392 242  242 MET MET R . n 
E 5 393 HIS 393 243  243 HIS HIS R . n 
E 5 394 LEU 394 244  244 LEU LEU R . n 
E 5 395 ASN 395 245  245 ASN ASN R . n 
E 5 396 LEU 396 246  246 LEU LEU R . n 
E 5 397 GLU 397 247  247 GLU GLU R . n 
E 5 398 VAL 398 248  248 VAL VAL R . n 
E 5 399 LEU 399 249  249 LEU LEU R . n 
E 5 400 TYR 400 250  250 TYR TYR R . n 
E 5 401 CYS 401 251  251 CYS CYS R . n 
E 5 402 HIS 402 252  252 HIS HIS R . n 
E 5 403 VAL 403 253  253 VAL VAL R . n 
E 5 404 TYR 404 254  254 TYR TYR R . n 
E 5 405 LEU 405 255  255 LEU LEU R . n 
E 5 406 VAL 406 256  256 VAL VAL R . n 
E 5 407 CYS 407 257  257 CYS CYS R . n 
E 5 408 MET 408 258  258 MET MET R . n 
E 5 409 SER 409 259  259 SER SER R . n 
E 5 410 LEU 410 260  260 LEU LEU R . n 
E 5 411 SER 411 261  261 SER SER R . n 
E 5 412 SER 412 262  262 SER SER R . n 
E 5 413 LEU 413 263  263 LEU LEU R . n 
E 5 414 ASN 414 264  264 ASN ASN R . n 
E 5 415 SER 415 265  265 SER SER R . n 
E 5 416 SER 416 266  266 SER SER R . n 
E 5 417 ALA 417 267  267 ALA ALA R . n 
E 5 418 ASN 418 268  268 ASN ASN R . n 
E 5 419 PRO 419 269  269 PRO PRO R . n 
E 5 420 ILE 420 270  270 ILE ILE R . n 
E 5 421 ILE 421 271  271 ILE ILE R . n 
E 5 422 TYR 422 272  272 TYR TYR R . n 
E 5 423 PHE 423 273  273 PHE PHE R . n 
E 5 424 PHE 424 274  274 PHE PHE R . n 
E 5 425 VAL 425 275  275 VAL VAL R . n 
E 5 426 GLY 426 276  276 GLY GLY R . n 
E 5 427 SER 427 277  ?   ?   ?   R . n 
E 5 428 PHE 428 278  ?   ?   ?   R . n 
E 5 429 ARG 429 279  ?   ?   ?   R . n 
E 5 430 GLN 430 280  ?   ?   ?   R . n 
E 5 431 ARG 431 281  ?   ?   ?   R . n 
E 5 432 GLN 432 282  ?   ?   ?   R . n 
E 5 433 ASN 433 283  ?   ?   ?   R . n 
E 5 434 ARG 434 284  ?   ?   ?   R . n 
E 5 435 GLN 435 285  ?   ?   ?   R . n 
E 5 436 ASN 436 286  ?   ?   ?   R . n 
E 5 437 LEU 437 287  ?   ?   ?   R . n 
E 5 438 LYS 438 288  ?   ?   ?   R . n 
E 5 439 LEU 439 289  ?   ?   ?   R . n 
E 5 440 VAL 440 290  ?   ?   ?   R . n 
E 5 441 LEU 441 291  ?   ?   ?   R . n 
E 5 442 GLN 442 292  ?   ?   ?   R . n 
E 5 443 ARG 443 293  ?   ?   ?   R . n 
E 5 444 ALA 444 294  ?   ?   ?   R . n 
E 5 445 LEU 445 295  ?   ?   ?   R . n 
E 5 446 GLN 446 296  ?   ?   ?   R . n 
E 5 447 ASP 447 297  ?   ?   ?   R . n 
E 5 448 LYS 448 298  ?   ?   ?   R . n 
E 5 449 PRO 449 299  ?   ?   ?   R . n 
E 5 450 GLU 450 300  ?   ?   ?   R . n 
E 5 451 VAL 451 301  ?   ?   ?   R . n 
E 5 452 ASP 452 302  ?   ?   ?   R . n 
E 5 453 LYS 453 303  ?   ?   ?   R . n 
E 5 454 GLY 454 304  ?   ?   ?   R . n 
E 5 455 GLU 455 305  ?   ?   ?   R . n 
E 5 456 GLY 456 306  ?   ?   ?   R . n 
E 5 457 GLN 457 307  ?   ?   ?   R . n 
E 5 458 LEU 458 308  ?   ?   ?   R . n 
E 5 459 PRO 459 309  ?   ?   ?   R . n 
E 5 460 GLU 460 310  ?   ?   ?   R . n 
E 5 461 GLU 461 311  ?   ?   ?   R . n 
E 5 462 SER 462 312  ?   ?   ?   R . n 
E 5 463 LEU 463 313  ?   ?   ?   R . n 
E 5 464 GLU 464 314  ?   ?   ?   R . n 
E 5 465 LEU 465 315  ?   ?   ?   R . n 
E 5 466 SER 466 316  ?   ?   ?   R . n 
E 5 467 GLY 467 317  ?   ?   ?   R . n 
E 5 468 SER 468 318  ?   ?   ?   R . n 
E 5 469 ARG 469 319  ?   ?   ?   R . n 
E 5 470 LEU 470 320  ?   ?   ?   R . n 
E 5 471 GLY 471 321  ?   ?   ?   R . n 
E 5 472 PRO 472 322  ?   ?   ?   R . n 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          A1LZU 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    501 
_pdbx_nonpoly_scheme.pdb_mon_id      A1LZU 
_pdbx_nonpoly_scheme.auth_mon_id     UNL 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 B GLU 28  ? CG  ? A GLU 28  CG  
2   1 Y 1 B GLU 28  ? CD  ? A GLU 28  CD  
3   1 Y 1 B GLU 28  ? OE1 ? A GLU 28  OE1 
4   1 Y 1 B GLU 28  ? OE2 ? A GLU 28  OE2 
5   1 Y 1 B ASP 42  ? CG  ? A ASP 42  CG  
6   1 Y 1 B ASP 42  ? OD1 ? A ASP 42  OD1 
7   1 Y 1 B ASP 42  ? OD2 ? A ASP 42  OD2 
8   1 Y 1 B LYS 51  ? CG  ? A LYS 51  CG  
9   1 Y 1 B LYS 51  ? CD  ? A LYS 51  CD  
10  1 Y 1 B LYS 51  ? CE  ? A LYS 51  CE  
11  1 Y 1 B LYS 51  ? NZ  ? A LYS 51  NZ  
12  1 Y 1 B PHE 70  ? CG  ? A PHE 70  CG  
13  1 Y 1 B PHE 70  ? CD1 ? A PHE 70  CD1 
14  1 Y 1 B PHE 70  ? CD2 ? A PHE 70  CD2 
15  1 Y 1 B PHE 70  ? CE1 ? A PHE 70  CE1 
16  1 Y 1 B PHE 70  ? CE2 ? A PHE 70  CE2 
17  1 Y 1 B PHE 70  ? CZ  ? A PHE 70  CZ  
18  1 Y 1 B GLU 71  ? CG  ? A GLU 71  CG  
19  1 Y 1 B GLU 71  ? CD  ? A GLU 71  CD  
20  1 Y 1 B GLU 71  ? OE1 ? A GLU 71  OE1 
21  1 Y 1 B GLU 71  ? OE2 ? A GLU 71  OE2 
22  1 Y 1 B LYS 73  ? CG  ? A LYS 73  CG  
23  1 Y 1 B LYS 73  ? CD  ? A LYS 73  CD  
24  1 Y 1 B LYS 73  ? CE  ? A LYS 73  CE  
25  1 Y 1 B LYS 73  ? NZ  ? A LYS 73  NZ  
26  1 Y 1 B GLN 75  ? CG  ? A GLN 75  CG  
27  1 Y 1 B GLN 75  ? CD  ? A GLN 75  CD  
28  1 Y 1 B GLN 75  ? OE1 ? A GLN 75  OE1 
29  1 Y 1 B GLN 75  ? NE2 ? A GLN 75  NE2 
30  1 Y 1 B ASP 77  ? CG  ? A ASP 77  CG  
31  1 Y 1 B ASP 77  ? OD1 ? A ASP 77  OD1 
32  1 Y 1 B ASP 77  ? OD2 ? A ASP 77  OD2 
33  1 Y 1 B LYS 78  ? CG  ? A LYS 78  CG  
34  1 Y 1 B LYS 78  ? CD  ? A LYS 78  CD  
35  1 Y 1 B LYS 78  ? CE  ? A LYS 78  CE  
36  1 Y 1 B LYS 78  ? NZ  ? A LYS 78  NZ  
37  1 Y 1 B ARG 94  ? CG  ? A ARG 94  CG  
38  1 Y 1 B ARG 94  ? CD  ? A ARG 94  CD  
39  1 Y 1 B ARG 94  ? NE  ? A ARG 94  NE  
40  1 Y 1 B ARG 94  ? CZ  ? A ARG 94  CZ  
41  1 Y 1 B ARG 94  ? NH1 ? A ARG 94  NH1 
42  1 Y 1 B ARG 94  ? NH2 ? A ARG 94  NH2 
43  1 Y 1 B ASP 102 ? CG  ? A ASP 102 CG  
44  1 Y 1 B ASP 102 ? OD1 ? A ASP 102 OD1 
45  1 Y 1 B ASP 102 ? OD2 ? A ASP 102 OD2 
46  1 Y 1 B ASN 116 ? CG  ? A ASN 116 CG  
47  1 Y 1 B ASN 116 ? OD1 ? A ASN 116 OD1 
48  1 Y 1 B ASN 116 ? ND2 ? A ASN 116 ND2 
49  1 Y 1 B GLU 120 ? CG  ? A GLU 120 CG  
50  1 Y 1 B GLU 120 ? CD  ? A GLU 120 CD  
51  1 Y 1 B GLU 120 ? OE1 ? A GLU 120 OE1 
52  1 Y 1 B GLU 120 ? OE2 ? A GLU 120 OE2 
53  1 Y 1 B ARG 132 ? CG  ? A ARG 132 CG  
54  1 Y 1 B ARG 132 ? CD  ? A ARG 132 CD  
55  1 Y 1 B ARG 132 ? NE  ? A ARG 132 NE  
56  1 Y 1 B ARG 132 ? CZ  ? A ARG 132 CZ  
57  1 Y 1 B ARG 132 ? NH1 ? A ARG 132 NH1 
58  1 Y 1 B ARG 132 ? NH2 ? A ARG 132 NH2 
59  1 Y 1 B ARG 135 ? CG  ? A ARG 135 CG  
60  1 Y 1 B ARG 135 ? CD  ? A ARG 135 CD  
61  1 Y 1 B ARG 135 ? NE  ? A ARG 135 NE  
62  1 Y 1 B ARG 135 ? CZ  ? A ARG 135 CZ  
63  1 Y 1 B ARG 135 ? NH1 ? A ARG 135 NH1 
64  1 Y 1 B ARG 135 ? NH2 ? A ARG 135 NH2 
65  1 Y 1 B LYS 152 ? CG  ? A LYS 152 CG  
66  1 Y 1 B LYS 152 ? CD  ? A LYS 152 CD  
67  1 Y 1 B LYS 152 ? CE  ? A LYS 152 CE  
68  1 Y 1 B LYS 152 ? NZ  ? A LYS 152 NZ  
69  1 Y 1 B LYS 157 ? CG  ? A LYS 157 CG  
70  1 Y 1 B LYS 157 ? CD  ? A LYS 157 CD  
71  1 Y 1 B LYS 157 ? CE  ? A LYS 157 CE  
72  1 Y 1 B LYS 157 ? NZ  ? A LYS 157 NZ  
73  1 Y 1 B LYS 159 ? CG  ? A LYS 159 CG  
74  1 Y 1 B LYS 159 ? CD  ? A LYS 159 CD  
75  1 Y 1 B LYS 159 ? CE  ? A LYS 159 CE  
76  1 Y 1 B LYS 159 ? NZ  ? A LYS 159 NZ  
77  1 Y 1 B GLU 161 ? CG  ? A GLU 161 CG  
78  1 Y 1 B GLU 161 ? CD  ? A GLU 161 CD  
79  1 Y 1 B GLU 161 ? OE1 ? A GLU 161 OE1 
80  1 Y 1 B GLU 161 ? OE2 ? A GLU 161 OE2 
81  1 Y 1 B ASP 162 ? CG  ? A ASP 162 CG  
82  1 Y 1 B ASP 162 ? OD1 ? A ASP 162 OD1 
83  1 Y 1 B ASP 162 ? OD2 ? A ASP 162 OD2 
84  1 Y 1 B GLU 166 ? CG  ? A GLU 166 CG  
85  1 Y 1 B GLU 166 ? CD  ? A GLU 166 CD  
86  1 Y 1 B GLU 166 ? OE1 ? A GLU 166 OE1 
87  1 Y 1 B GLU 166 ? OE2 ? A GLU 166 OE2 
88  1 Y 1 B ARG 169 ? CG  ? A ARG 169 CG  
89  1 Y 1 B ARG 169 ? CD  ? A ARG 169 CD  
90  1 Y 1 B ARG 169 ? NE  ? A ARG 169 NE  
91  1 Y 1 B ARG 169 ? CZ  ? A ARG 169 CZ  
92  1 Y 1 B ARG 169 ? NH1 ? A ARG 169 NH1 
93  1 Y 1 B ARG 169 ? NH2 ? A ARG 169 NH2 
94  1 Y 1 B GLU 174 ? CG  ? A GLU 174 CG  
95  1 Y 1 B GLU 174 ? CD  ? A GLU 174 CD  
96  1 Y 1 B GLU 174 ? OE1 ? A GLU 174 OE1 
97  1 Y 1 B GLU 174 ? OE2 ? A GLU 174 OE2 
98  1 Y 1 B ASP 175 ? CG  ? A ASP 175 CG  
99  1 Y 1 B ASP 175 ? OD1 ? A ASP 175 OD1 
100 1 Y 1 B ASP 175 ? OD2 ? A ASP 175 OD2 
101 1 Y 1 B THR 177 ? OG1 ? A THR 177 OG1 
102 1 Y 1 B THR 177 ? CG2 ? A THR 177 CG2 
103 1 Y 1 B PRO 178 ? CG  ? A PRO 178 CG  
104 1 Y 1 B PRO 178 ? CD  ? A PRO 178 CD  
105 1 Y 1 B GLU 179 ? CG  ? A GLU 179 CG  
106 1 Y 1 B GLU 179 ? CD  ? A GLU 179 CD  
107 1 Y 1 B GLU 179 ? OE1 ? A GLU 179 OE1 
108 1 Y 1 B GLU 179 ? OE2 ? A GLU 179 OE2 
109 1 Y 1 B PRO 180 ? CG  ? A PRO 180 CG  
110 1 Y 1 B PRO 180 ? CD  ? A PRO 180 CD  
111 1 Y 1 B ASP 183 ? CG  ? A ASP 183 CG  
112 1 Y 1 B ASP 183 ? OD1 ? A ASP 183 OD1 
113 1 Y 1 B ASP 183 ? OD2 ? A ASP 183 OD2 
114 1 Y 1 B LYS 195 ? CG  ? A LYS 195 CG  
115 1 Y 1 B LYS 195 ? CD  ? A LYS 195 CD  
116 1 Y 1 B LYS 195 ? CE  ? A LYS 195 CE  
117 1 Y 1 B LYS 195 ? NZ  ? A LYS 195 NZ  
118 1 Y 1 B ASP 206 ? CG  ? A ASP 206 CG  
119 1 Y 1 B ASP 206 ? OD1 ? A ASP 206 OD1 
120 1 Y 1 B ASP 206 ? OD2 ? A ASP 206 OD2 
121 1 Y 1 B ARG 208 ? CG  ? A ARG 208 CG  
122 1 Y 1 B ARG 208 ? CD  ? A ARG 208 CD  
123 1 Y 1 B ARG 208 ? NE  ? A ARG 208 NE  
124 1 Y 1 B ARG 208 ? CZ  ? A ARG 208 CZ  
125 1 Y 1 B ARG 208 ? NH1 ? A ARG 208 NH1 
126 1 Y 1 B ARG 208 ? NH2 ? A ARG 208 NH2 
127 1 Y 1 B VAL 219 ? CG1 ? A VAL 219 CG1 
128 1 Y 1 B VAL 219 ? CG2 ? A VAL 219 CG2 
129 1 Y 1 B ASP 220 ? CG  ? A ASP 220 CG  
130 1 Y 1 B ASP 220 ? OD1 ? A ASP 220 OD1 
131 1 Y 1 B ASP 220 ? OD2 ? A ASP 220 OD2 
132 1 Y 1 B GLU 222 ? CG  ? A GLU 222 CG  
133 1 Y 1 B GLU 222 ? CD  ? A GLU 222 CD  
134 1 Y 1 B GLU 222 ? OE1 ? A GLU 222 OE1 
135 1 Y 1 B GLU 222 ? OE2 ? A GLU 222 OE2 
136 1 Y 1 C GLU 3   ? CG  ? B GLU 21  CG  
137 1 Y 1 C GLU 3   ? CD  ? B GLU 21  CD  
138 1 Y 1 C GLU 3   ? OE1 ? B GLU 21  OE1 
139 1 Y 1 C GLU 3   ? OE2 ? B GLU 21  OE2 
140 1 Y 1 C LEU 4   ? CG  ? B LEU 22  CG  
141 1 Y 1 C LEU 4   ? CD1 ? B LEU 22  CD1 
142 1 Y 1 C LEU 4   ? CD2 ? B LEU 22  CD2 
143 1 Y 1 C ASP 5   ? CG  ? B ASP 23  CG  
144 1 Y 1 C ASP 5   ? OD1 ? B ASP 23  OD1 
145 1 Y 1 C ASP 5   ? OD2 ? B ASP 23  OD2 
146 1 Y 1 C GLN 6   ? CG  ? B GLN 24  CG  
147 1 Y 1 C GLN 6   ? CD  ? B GLN 24  CD  
148 1 Y 1 C GLN 6   ? OE1 ? B GLN 24  OE1 
149 1 Y 1 C GLN 6   ? NE2 ? B GLN 24  NE2 
150 1 Y 1 C LEU 7   ? CG  ? B LEU 25  CG  
151 1 Y 1 C LEU 7   ? CD1 ? B LEU 25  CD1 
152 1 Y 1 C LEU 7   ? CD2 ? B LEU 25  CD2 
153 1 Y 1 C ARG 8   ? CG  ? B ARG 26  CG  
154 1 Y 1 C ARG 8   ? CD  ? B ARG 26  CD  
155 1 Y 1 C ARG 8   ? NE  ? B ARG 26  NE  
156 1 Y 1 C ARG 8   ? CZ  ? B ARG 26  CZ  
157 1 Y 1 C ARG 8   ? NH1 ? B ARG 26  NH1 
158 1 Y 1 C ARG 8   ? NH2 ? B ARG 26  NH2 
159 1 Y 1 C GLN 9   ? CG  ? B GLN 27  CG  
160 1 Y 1 C GLN 9   ? CD  ? B GLN 27  CD  
161 1 Y 1 C GLN 9   ? OE1 ? B GLN 27  OE1 
162 1 Y 1 C GLN 9   ? NE2 ? B GLN 27  NE2 
163 1 Y 1 C GLU 10  ? CG  ? B GLU 28  CG  
164 1 Y 1 C GLU 10  ? CD  ? B GLU 28  CD  
165 1 Y 1 C GLU 10  ? OE1 ? B GLU 28  OE1 
166 1 Y 1 C GLU 10  ? OE2 ? B GLU 28  OE2 
167 1 Y 1 C GLU 12  ? CG  ? B GLU 30  CG  
168 1 Y 1 C GLU 12  ? CD  ? B GLU 30  CD  
169 1 Y 1 C GLU 12  ? OE1 ? B GLU 30  OE1 
170 1 Y 1 C GLU 12  ? OE2 ? B GLU 30  OE2 
171 1 Y 1 C GLN 13  ? CG  ? B GLN 31  CG  
172 1 Y 1 C GLN 13  ? CD  ? B GLN 31  CD  
173 1 Y 1 C GLN 13  ? OE1 ? B GLN 31  OE1 
174 1 Y 1 C GLN 13  ? NE2 ? B GLN 31  NE2 
175 1 Y 1 C LYS 15  ? CG  ? B LYS 33  CG  
176 1 Y 1 C LYS 15  ? CD  ? B LYS 33  CD  
177 1 Y 1 C LYS 15  ? CE  ? B LYS 33  CE  
178 1 Y 1 C LYS 15  ? NZ  ? B LYS 33  NZ  
179 1 Y 1 C ASN 16  ? CG  ? B ASN 34  CG  
180 1 Y 1 C ASN 16  ? OD1 ? B ASN 34  OD1 
181 1 Y 1 C ASN 16  ? ND2 ? B ASN 34  ND2 
182 1 Y 1 C ARG 19  ? CG  ? B ARG 37  CG  
183 1 Y 1 C ARG 19  ? CD  ? B ARG 37  CD  
184 1 Y 1 C ARG 19  ? NE  ? B ARG 37  NE  
185 1 Y 1 C ARG 19  ? CZ  ? B ARG 37  CZ  
186 1 Y 1 C ARG 19  ? NH1 ? B ARG 37  NH1 
187 1 Y 1 C ARG 19  ? NH2 ? B ARG 37  NH2 
188 1 Y 1 C ASP 20  ? CG  ? B ASP 38  CG  
189 1 Y 1 C ASP 20  ? OD1 ? B ASP 38  OD1 
190 1 Y 1 C ASP 20  ? OD2 ? B ASP 38  OD2 
191 1 Y 1 C LYS 23  ? CG  ? B LYS 41  CG  
192 1 Y 1 C LYS 23  ? CD  ? B LYS 41  CD  
193 1 Y 1 C LYS 23  ? CE  ? B LYS 41  CE  
194 1 Y 1 C LYS 23  ? NZ  ? B LYS 41  NZ  
195 1 Y 1 C ASP 38  ? CG  ? B ASP 56  CG  
196 1 Y 1 C ASP 38  ? OD1 ? B ASP 56  OD1 
197 1 Y 1 C ASP 38  ? OD2 ? B ASP 56  OD2 
198 1 Y 1 C ARG 42  ? CG  ? B ARG 60  CG  
199 1 Y 1 C ARG 42  ? CD  ? B ARG 60  CD  
200 1 Y 1 C ARG 42  ? NE  ? B ARG 60  NE  
201 1 Y 1 C ARG 42  ? CZ  ? B ARG 60  CZ  
202 1 Y 1 C ARG 42  ? NH1 ? B ARG 60  NH1 
203 1 Y 1 C ARG 42  ? NH2 ? B ARG 60  NH2 
204 1 Y 1 C GLN 44  ? CG  ? B GLN 62  CG  
205 1 Y 1 C GLN 44  ? CD  ? B GLN 62  CD  
206 1 Y 1 C GLN 44  ? OE1 ? B GLN 62  OE1 
207 1 Y 1 C GLN 44  ? NE2 ? B GLN 62  NE2 
208 1 Y 1 C ARG 46  ? CG  ? B ARG 64  CG  
209 1 Y 1 C ARG 46  ? CD  ? B ARG 64  CD  
210 1 Y 1 C ARG 46  ? NE  ? B ARG 64  NE  
211 1 Y 1 C ARG 46  ? CZ  ? B ARG 64  CZ  
212 1 Y 1 C ARG 46  ? NH1 ? B ARG 64  NH1 
213 1 Y 1 C ARG 46  ? NH2 ? B ARG 64  NH2 
214 1 Y 1 C ARG 96  ? CG  ? B ARG 114 CG  
215 1 Y 1 C ARG 96  ? CD  ? B ARG 114 CD  
216 1 Y 1 C ARG 96  ? NE  ? B ARG 114 NE  
217 1 Y 1 C ARG 96  ? CZ  ? B ARG 114 CZ  
218 1 Y 1 C ARG 96  ? NH1 ? B ARG 114 NH1 
219 1 Y 1 C ARG 96  ? NH2 ? B ARG 114 NH2 
220 1 Y 1 C SER 97  ? OG  ? B SER 115 OG  
221 1 Y 1 C ASP 170 ? CG  ? B ASP 188 CG  
222 1 Y 1 C ASP 170 ? OD1 ? B ASP 188 OD1 
223 1 Y 1 C ASP 170 ? OD2 ? B ASP 188 OD2 
224 1 Y 1 C GLU 172 ? CG  ? B GLU 190 CG  
225 1 Y 1 C GLU 172 ? CD  ? B GLU 190 CD  
226 1 Y 1 C GLU 172 ? OE1 ? B GLU 190 OE1 
227 1 Y 1 C GLU 172 ? OE2 ? B GLU 190 OE2 
228 1 Y 1 C THR 173 ? OG1 ? B THR 191 OG1 
229 1 Y 1 C THR 173 ? CG2 ? B THR 191 CG2 
230 1 Y 1 C ARG 197 ? CG  ? B ARG 215 CG  
231 1 Y 1 C ARG 197 ? CD  ? B ARG 215 CD  
232 1 Y 1 C ARG 197 ? NE  ? B ARG 215 NE  
233 1 Y 1 C ARG 197 ? CZ  ? B ARG 215 CZ  
234 1 Y 1 C ARG 197 ? NH1 ? B ARG 215 NH1 
235 1 Y 1 C ARG 197 ? NH2 ? B ARG 215 NH2 
236 1 Y 1 C ARG 214 ? CG  ? B ARG 232 CG  
237 1 Y 1 C ARG 214 ? CD  ? B ARG 232 CD  
238 1 Y 1 C ARG 214 ? NE  ? B ARG 232 NE  
239 1 Y 1 C ARG 214 ? CZ  ? B ARG 232 CZ  
240 1 Y 1 C ARG 214 ? NH1 ? B ARG 232 NH1 
241 1 Y 1 C ARG 214 ? NH2 ? B ARG 232 NH2 
242 1 Y 1 C GLU 215 ? CG  ? B GLU 233 CG  
243 1 Y 1 C GLU 215 ? CD  ? B GLU 233 CD  
244 1 Y 1 C GLU 215 ? OE1 ? B GLU 233 OE1 
245 1 Y 1 C GLU 215 ? OE2 ? B GLU 233 OE2 
246 1 Y 1 C MET 217 ? CG  ? B MET 235 CG  
247 1 Y 1 C MET 217 ? SD  ? B MET 235 SD  
248 1 Y 1 C MET 217 ? CE  ? B MET 235 CE  
249 1 Y 1 C THR 221 ? OG1 ? B THR 239 OG1 
250 1 Y 1 C THR 221 ? CG2 ? B THR 239 CG2 
251 1 Y 1 C SER 245 ? OG  ? B SER 263 OG  
252 1 Y 1 C SER 265 ? OG  ? B SER 283 OG  
253 1 Y 1 C ASP 267 ? CG  ? B ASP 285 CG  
254 1 Y 1 C ASP 267 ? OD1 ? B ASP 285 OD1 
255 1 Y 1 C ASP 267 ? OD2 ? B ASP 285 OD2 
256 1 Y 1 C ASP 303 ? CG  ? B ASP 321 CG  
257 1 Y 1 C ASP 303 ? OD1 ? B ASP 321 OD1 
258 1 Y 1 C ASP 303 ? OD2 ? B ASP 321 OD2 
259 1 Y 1 C SER 331 ? OG  ? B SER 349 OG  
260 1 Y 1 D GLN 11  ? CG  ? C GLN 11  CG  
261 1 Y 1 D GLN 11  ? CD  ? C GLN 11  CD  
262 1 Y 1 D GLN 11  ? OE1 ? C GLN 11  OE1 
263 1 Y 1 D GLN 11  ? NE2 ? C GLN 11  NE2 
264 1 Y 1 D ARG 13  ? CG  ? C ARG 13  CG  
265 1 Y 1 D ARG 13  ? CD  ? C ARG 13  CD  
266 1 Y 1 D ARG 13  ? NE  ? C ARG 13  NE  
267 1 Y 1 D ARG 13  ? CZ  ? C ARG 13  CZ  
268 1 Y 1 D ARG 13  ? NH1 ? C ARG 13  NH1 
269 1 Y 1 D ARG 13  ? NH2 ? C ARG 13  NH2 
270 1 Y 1 D LYS 14  ? CG  ? C LYS 14  CG  
271 1 Y 1 D LYS 14  ? CD  ? C LYS 14  CD  
272 1 Y 1 D LYS 14  ? CE  ? C LYS 14  CE  
273 1 Y 1 D LYS 14  ? NZ  ? C LYS 14  NZ  
274 1 Y 1 D LEU 15  ? CG  ? C LEU 15  CG  
275 1 Y 1 D LEU 15  ? CD1 ? C LEU 15  CD1 
276 1 Y 1 D LEU 15  ? CD2 ? C LEU 15  CD2 
277 1 Y 1 D GLU 17  ? CG  ? C GLU 17  CG  
278 1 Y 1 D GLU 17  ? CD  ? C GLU 17  CD  
279 1 Y 1 D GLU 17  ? OE1 ? C GLU 17  OE1 
280 1 Y 1 D GLU 17  ? OE2 ? C GLU 17  OE2 
281 1 Y 1 D LYS 20  ? CG  ? C LYS 20  CG  
282 1 Y 1 D LYS 20  ? CD  ? C LYS 20  CD  
283 1 Y 1 D LYS 20  ? CE  ? C LYS 20  CE  
284 1 Y 1 D LYS 20  ? NZ  ? C LYS 20  NZ  
285 1 Y 1 D MET 21  ? CG  ? C MET 21  CG  
286 1 Y 1 D MET 21  ? SD  ? C MET 21  SD  
287 1 Y 1 D MET 21  ? CE  ? C MET 21  CE  
288 1 Y 1 D ASN 24  ? CG  ? C ASN 24  CG  
289 1 Y 1 D ASN 24  ? OD1 ? C ASN 24  OD1 
290 1 Y 1 D ASN 24  ? ND2 ? C ASN 24  ND2 
291 1 Y 1 D LYS 46  ? CG  ? C LYS 46  CG  
292 1 Y 1 D LYS 46  ? CD  ? C LYS 46  CD  
293 1 Y 1 D LYS 46  ? CE  ? C LYS 46  CE  
294 1 Y 1 D LYS 46  ? NZ  ? C LYS 46  NZ  
295 1 Y 1 D VAL 54  ? CG1 ? C VAL 54  CG1 
296 1 Y 1 D VAL 54  ? CG2 ? C VAL 54  CG2 
297 1 Y 1 D GLU 58  ? CG  ? C GLU 58  CG  
298 1 Y 1 D GLU 58  ? CD  ? C GLU 58  CD  
299 1 Y 1 D GLU 58  ? OE1 ? C GLU 58  OE1 
300 1 Y 1 D GLU 58  ? OE2 ? C GLU 58  OE2 
301 1 Y 1 E GLU 42  ? CG  ? D GLU 42  CG  
302 1 Y 1 E GLU 42  ? CD  ? D GLU 42  CD  
303 1 Y 1 E GLU 42  ? OE1 ? D GLU 42  OE1 
304 1 Y 1 E GLU 42  ? OE2 ? D GLU 42  OE2 
305 1 Y 1 E LYS 43  ? CG  ? D LYS 43  CG  
306 1 Y 1 E LYS 43  ? CD  ? D LYS 43  CD  
307 1 Y 1 E LYS 43  ? CE  ? D LYS 43  CE  
308 1 Y 1 E LYS 43  ? NZ  ? D LYS 43  NZ  
309 1 Y 1 E LYS 76  ? CG  ? D LYS 76  CG  
310 1 Y 1 E LYS 76  ? CD  ? D LYS 76  CD  
311 1 Y 1 E LYS 76  ? CE  ? D LYS 76  CE  
312 1 Y 1 E LYS 76  ? NZ  ? D LYS 76  NZ  
313 1 Y 1 E GLU 89  ? CG  ? D GLU 89  CG  
314 1 Y 1 E GLU 89  ? CD  ? D GLU 89  CD  
315 1 Y 1 E GLU 89  ? OE1 ? D GLU 89  OE1 
316 1 Y 1 E GLU 89  ? OE2 ? D GLU 89  OE2 
317 1 Y 1 E THR 91  ? OG1 ? D THR 91  OG1 
318 1 Y 1 E THR 91  ? CG2 ? D THR 91  CG2 
319 1 Y 1 E VAL 119 ? CG1 ? D VAL 119 CG1 
320 1 Y 1 E VAL 119 ? CG2 ? D VAL 119 CG2 
321 1 Y 1 E THR 132 ? OG1 ? D THR 144 OG1 
322 1 Y 1 E THR 132 ? CG2 ? D THR 144 CG2 
323 1 Y 1 E SER 134 ? OG  ? D SER 146 OG  
324 1 Y 1 E VAL 137 ? CG1 ? D VAL 149 CG1 
325 1 Y 1 E VAL 137 ? CG2 ? D VAL 149 CG2 
326 1 Y 1 E GLU 141 ? CG  ? D GLU 153 CG  
327 1 Y 1 E GLU 141 ? CD  ? D GLU 153 CD  
328 1 Y 1 E GLU 141 ? OE1 ? D GLU 153 OE1 
329 1 Y 1 E GLU 141 ? OE2 ? D GLU 153 OE2 
330 1 Y 1 E ARG 206 ? CG  ? D ARG 218 CG  
331 1 Y 1 E ARG 206 ? CD  ? D ARG 218 CD  
332 1 Y 1 E ARG 206 ? NE  ? D ARG 218 NE  
333 1 Y 1 E ARG 206 ? CZ  ? D ARG 218 CZ  
334 1 Y 1 E ARG 206 ? NH1 ? D ARG 218 NH1 
335 1 Y 1 E ARG 206 ? NH2 ? D ARG 218 NH2 
336 1 Y 1 E GLU 208 ? CG  ? D GLU 220 CG  
337 1 Y 1 E GLU 208 ? CD  ? D GLU 220 CD  
338 1 Y 1 E GLU 208 ? OE1 ? D GLU 220 OE1 
339 1 Y 1 E GLU 208 ? OE2 ? D GLU 220 OE2 
340 1 Y 1 E GLU 210 ? CG  ? D GLU 222 CG  
341 1 Y 1 E GLU 210 ? CD  ? D GLU 222 CD  
342 1 Y 1 E GLU 210 ? OE1 ? D GLU 222 OE1 
343 1 Y 1 E GLU 210 ? OE2 ? D GLU 222 OE2 
344 1 Y 1 E GLU 234 ? CG  ? D GLU 246 CG  
345 1 Y 1 E GLU 234 ? CD  ? D GLU 246 CD  
346 1 Y 1 E GLU 234 ? OE1 ? D GLU 246 OE1 
347 1 Y 1 E GLU 234 ? OE2 ? D GLU 246 OE2 
348 1 Y 1 R GLN 26  ? CG  ? E GLN 176 CG  
349 1 Y 1 R GLN 26  ? CD  ? E GLN 176 CD  
350 1 Y 1 R GLN 26  ? OE1 ? E GLN 176 OE1 
351 1 Y 1 R GLN 26  ? NE2 ? E GLN 176 NE2 
352 1 Y 1 R THR 27  ? OG1 ? E THR 177 OG1 
353 1 Y 1 R THR 27  ? CG2 ? E THR 177 CG2 
354 1 Y 1 R LEU 28  ? CG  ? E LEU 178 CG  
355 1 Y 1 R LEU 28  ? CD1 ? E LEU 178 CD1 
356 1 Y 1 R LEU 28  ? CD2 ? E LEU 178 CD2 
357 1 Y 1 R SER 29  ? OG  ? E SER 179 OG  
358 1 Y 1 R PHE 30  ? CG  ? E PHE 180 CG  
359 1 Y 1 R PHE 30  ? CD1 ? E PHE 180 CD1 
360 1 Y 1 R PHE 30  ? CD2 ? E PHE 180 CD2 
361 1 Y 1 R PHE 30  ? CE1 ? E PHE 180 CE1 
362 1 Y 1 R PHE 30  ? CE2 ? E PHE 180 CE2 
363 1 Y 1 R PHE 30  ? CZ  ? E PHE 180 CZ  
364 1 Y 1 R THR 31  ? OG1 ? E THR 181 OG1 
365 1 Y 1 R THR 31  ? CG2 ? E THR 181 CG2 
366 1 Y 1 R VAL 32  ? CG1 ? E VAL 182 CG1 
367 1 Y 1 R VAL 32  ? CG2 ? E VAL 182 CG2 
368 1 Y 1 R LEU 33  ? CG  ? E LEU 183 CG  
369 1 Y 1 R LEU 33  ? CD1 ? E LEU 183 CD1 
370 1 Y 1 R LEU 33  ? CD2 ? E LEU 183 CD2 
371 1 Y 1 R THR 34  ? OG1 ? E THR 184 OG1 
372 1 Y 1 R THR 34  ? CG2 ? E THR 184 CG2 
373 1 Y 1 R CYS 35  ? SG  ? E CYS 185 SG  
374 1 Y 1 R ILE 36  ? CG1 ? E ILE 186 CG1 
375 1 Y 1 R ILE 36  ? CG2 ? E ILE 186 CG2 
376 1 Y 1 R ILE 36  ? CD1 ? E ILE 186 CD1 
377 1 Y 1 R ILE 37  ? CG1 ? E ILE 187 CG1 
378 1 Y 1 R ILE 37  ? CG2 ? E ILE 187 CG2 
379 1 Y 1 R ILE 37  ? CD1 ? E ILE 187 CD1 
380 1 Y 1 R SER 38  ? OG  ? E SER 188 OG  
381 1 Y 1 R LEU 39  ? CG  ? E LEU 189 CG  
382 1 Y 1 R LEU 39  ? CD1 ? E LEU 189 CD1 
383 1 Y 1 R LEU 39  ? CD2 ? E LEU 189 CD2 
384 1 Y 1 R VAL 40  ? CG1 ? E VAL 190 CG1 
385 1 Y 1 R VAL 40  ? CG2 ? E VAL 190 CG2 
386 1 Y 1 R LEU 42  ? CG  ? E LEU 192 CG  
387 1 Y 1 R LEU 42  ? CD1 ? E LEU 192 CD1 
388 1 Y 1 R LEU 42  ? CD2 ? E LEU 192 CD2 
389 1 Y 1 R THR 43  ? OG1 ? E THR 193 OG1 
390 1 Y 1 R THR 43  ? CG2 ? E THR 193 CG2 
391 1 Y 1 R ASN 45  ? CG  ? E ASN 195 CG  
392 1 Y 1 R ASN 45  ? OD1 ? E ASN 195 OD1 
393 1 Y 1 R ASN 45  ? ND2 ? E ASN 195 ND2 
394 1 Y 1 R VAL 47  ? CG1 ? E VAL 197 CG1 
395 1 Y 1 R VAL 47  ? CG2 ? E VAL 197 CG2 
396 1 Y 1 R VAL 48  ? CG1 ? E VAL 198 CG1 
397 1 Y 1 R VAL 48  ? CG2 ? E VAL 198 CG2 
398 1 Y 1 R LEU 49  ? CG  ? E LEU 199 CG  
399 1 Y 1 R LEU 49  ? CD1 ? E LEU 199 CD1 
400 1 Y 1 R LEU 49  ? CD2 ? E LEU 199 CD2 
401 1 Y 1 R TRP 50  ? CG  ? E TRP 200 CG  
402 1 Y 1 R TRP 50  ? CD1 ? E TRP 200 CD1 
403 1 Y 1 R TRP 50  ? CD2 ? E TRP 200 CD2 
404 1 Y 1 R TRP 50  ? NE1 ? E TRP 200 NE1 
405 1 Y 1 R TRP 50  ? CE2 ? E TRP 200 CE2 
406 1 Y 1 R TRP 50  ? CE3 ? E TRP 200 CE3 
407 1 Y 1 R TRP 50  ? CZ2 ? E TRP 200 CZ2 
408 1 Y 1 R TRP 50  ? CZ3 ? E TRP 200 CZ3 
409 1 Y 1 R TRP 50  ? CH2 ? E TRP 200 CH2 
410 1 Y 1 R LEU 51  ? CG  ? E LEU 201 CG  
411 1 Y 1 R LEU 51  ? CD1 ? E LEU 201 CD1 
412 1 Y 1 R LEU 51  ? CD2 ? E LEU 201 CD2 
413 1 Y 1 R TYR 54  ? CG  ? E TYR 204 CG  
414 1 Y 1 R TYR 54  ? CD1 ? E TYR 204 CD1 
415 1 Y 1 R TYR 54  ? CD2 ? E TYR 204 CD2 
416 1 Y 1 R TYR 54  ? CE1 ? E TYR 204 CE1 
417 1 Y 1 R TYR 54  ? CE2 ? E TYR 204 CE2 
418 1 Y 1 R TYR 54  ? CZ  ? E TYR 204 CZ  
419 1 Y 1 R TYR 54  ? OH  ? E TYR 204 OH  
420 1 Y 1 R ARG 55  ? CG  ? E ARG 205 CG  
421 1 Y 1 R ARG 55  ? CD  ? E ARG 205 CD  
422 1 Y 1 R ARG 55  ? NE  ? E ARG 205 NE  
423 1 Y 1 R ARG 55  ? CZ  ? E ARG 205 CZ  
424 1 Y 1 R ARG 55  ? NH1 ? E ARG 205 NH1 
425 1 Y 1 R ARG 55  ? NH2 ? E ARG 205 NH2 
426 1 Y 1 R MET 56  ? CG  ? E MET 206 CG  
427 1 Y 1 R MET 56  ? SD  ? E MET 206 SD  
428 1 Y 1 R MET 56  ? CE  ? E MET 206 CE  
429 1 Y 1 R ARG 57  ? CG  ? E ARG 207 CG  
430 1 Y 1 R ARG 57  ? CD  ? E ARG 207 CD  
431 1 Y 1 R ARG 57  ? NE  ? E ARG 207 NE  
432 1 Y 1 R ARG 57  ? CZ  ? E ARG 207 CZ  
433 1 Y 1 R ARG 57  ? NH1 ? E ARG 207 NH1 
434 1 Y 1 R ARG 57  ? NH2 ? E ARG 207 NH2 
435 1 Y 1 R ARG 58  ? CG  ? E ARG 208 CG  
436 1 Y 1 R ARG 58  ? CD  ? E ARG 208 CD  
437 1 Y 1 R ARG 58  ? NE  ? E ARG 208 NE  
438 1 Y 1 R ARG 58  ? CZ  ? E ARG 208 CZ  
439 1 Y 1 R ARG 58  ? NH1 ? E ARG 208 NH1 
440 1 Y 1 R ARG 58  ? NH2 ? E ARG 208 NH2 
441 1 Y 1 R ASN 59  ? CG  ? E ASN 209 CG  
442 1 Y 1 R ASN 59  ? OD1 ? E ASN 209 OD1 
443 1 Y 1 R ASN 59  ? ND2 ? E ASN 209 ND2 
444 1 Y 1 R PRO 84  ? CG  ? E PRO 234 CG  
445 1 Y 1 R PRO 84  ? CD  ? E PRO 234 CD  
446 1 Y 1 R ASN 89  ? CG  ? E ASN 239 CG  
447 1 Y 1 R ASN 89  ? OD1 ? E ASN 239 OD1 
448 1 Y 1 R ASN 89  ? ND2 ? E ASN 239 ND2 
449 1 Y 1 R ILE 90  ? CG1 ? E ILE 240 CG1 
450 1 Y 1 R ILE 90  ? CG2 ? E ILE 240 CG2 
451 1 Y 1 R ILE 90  ? CD1 ? E ILE 240 CD1 
452 1 Y 1 R SER 91  ? OG  ? E SER 241 OG  
453 1 Y 1 R LEU 93  ? CG  ? E LEU 243 CG  
454 1 Y 1 R LEU 93  ? CD1 ? E LEU 243 CD1 
455 1 Y 1 R LEU 93  ? CD2 ? E LEU 243 CD2 
456 1 Y 1 R ILE 94  ? CG1 ? E ILE 244 CG1 
457 1 Y 1 R ILE 94  ? CG2 ? E ILE 244 CG2 
458 1 Y 1 R ILE 94  ? CD1 ? E ILE 244 CD1 
459 1 Y 1 R SER 154 ? OG  ? E SER 304 OG  
460 1 Y 1 R GLU 157 ? CG  ? E GLU 307 CG  
461 1 Y 1 R GLU 157 ? CD  ? E GLU 307 CD  
462 1 Y 1 R GLU 157 ? OE1 ? E GLU 307 OE1 
463 1 Y 1 R GLU 157 ? OE2 ? E GLU 307 OE2 
464 1 Y 1 R THR 175 ? OG1 ? E THR 325 OG1 
465 1 Y 1 R THR 175 ? CG2 ? E THR 325 CG2 
466 1 Y 1 R SER 176 ? OG  ? E SER 326 OG  
467 1 Y 1 R ASP 177 ? CG  ? E ASP 327 CG  
468 1 Y 1 R ASP 177 ? OD1 ? E ASP 327 OD1 
469 1 Y 1 R ASP 177 ? OD2 ? E ASP 327 OD2 
470 1 Y 1 R SER 206 ? OG  ? E SER 356 OG  
471 1 Y 1 R ARG 207 ? CG  ? E ARG 357 CG  
472 1 Y 1 R ARG 207 ? CD  ? E ARG 357 CD  
473 1 Y 1 R ARG 207 ? NE  ? E ARG 357 NE  
474 1 Y 1 R ARG 207 ? CZ  ? E ARG 357 CZ  
475 1 Y 1 R ARG 207 ? NH1 ? E ARG 357 NH1 
476 1 Y 1 R ARG 207 ? NH2 ? E ARG 357 NH2 
477 1 Y 1 R LYS 208 ? CG  ? E LYS 358 CG  
478 1 Y 1 R LYS 208 ? CD  ? E LYS 358 CD  
479 1 Y 1 R LYS 208 ? CE  ? E LYS 358 CE  
480 1 Y 1 R LYS 208 ? NZ  ? E LYS 358 NZ  
481 1 Y 1 R MET 209 ? CG  ? E MET 359 CG  
482 1 Y 1 R MET 209 ? SD  ? E MET 359 SD  
483 1 Y 1 R MET 209 ? CE  ? E MET 359 CE  
484 1 Y 1 R PRO 210 ? CG  ? E PRO 360 CG  
485 1 Y 1 R PRO 210 ? CD  ? E PRO 360 CD  
486 1 Y 1 R MET 242 ? CG  ? E MET 392 CG  
487 1 Y 1 R MET 242 ? SD  ? E MET 392 SD  
488 1 Y 1 R MET 242 ? CE  ? E MET 392 CE  
489 1 Y 1 R HIS 243 ? CG  ? E HIS 393 CG  
490 1 Y 1 R HIS 243 ? ND1 ? E HIS 393 ND1 
491 1 Y 1 R HIS 243 ? CD2 ? E HIS 393 CD2 
492 1 Y 1 R HIS 243 ? CE1 ? E HIS 393 CE1 
493 1 Y 1 R HIS 243 ? NE2 ? E HIS 393 NE2 
494 1 Y 1 R LEU 244 ? CG  ? E LEU 394 CG  
495 1 Y 1 R LEU 244 ? CD1 ? E LEU 394 CD1 
496 1 Y 1 R LEU 244 ? CD2 ? E LEU 394 CD2 
497 1 Y 1 R ASN 245 ? CG  ? E ASN 395 CG  
498 1 Y 1 R ASN 245 ? OD1 ? E ASN 395 OD1 
499 1 Y 1 R ASN 245 ? ND2 ? E ASN 395 ND2 
500 1 Y 1 R LEU 246 ? CG  ? E LEU 396 CG  
501 1 Y 1 R LEU 246 ? CD1 ? E LEU 396 CD1 
502 1 Y 1 R LEU 246 ? CD2 ? E LEU 396 CD2 
503 1 Y 1 R GLU 247 ? CG  ? E GLU 397 CG  
504 1 Y 1 R GLU 247 ? CD  ? E GLU 397 CD  
505 1 Y 1 R GLU 247 ? OE1 ? E GLU 397 OE1 
506 1 Y 1 R GLU 247 ? OE2 ? E GLU 397 OE2 
507 1 Y 1 R VAL 248 ? CG1 ? E VAL 398 CG1 
508 1 Y 1 R VAL 248 ? CG2 ? E VAL 398 CG2 
509 1 Y 1 R CYS 251 ? SG  ? E CYS 401 SG  
510 1 Y 1 R HIS 252 ? CG  ? E HIS 402 CG  
511 1 Y 1 R HIS 252 ? ND1 ? E HIS 402 ND1 
512 1 Y 1 R HIS 252 ? CD2 ? E HIS 402 CD2 
513 1 Y 1 R HIS 252 ? CE1 ? E HIS 402 CE1 
514 1 Y 1 R HIS 252 ? NE2 ? E HIS 402 NE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8YRG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8YRG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8YRG 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8YRG 
_struct.title                        'CryoEM structure of fospropofol-bound MRGPRX4-Gq complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8YRG 
_struct_keywords.text            'GPCR-G protein complex, SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8YRG        8YRG   ? 1 ? 1  
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2  
3 UNP GBG2_HUMAN  P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1  
4 PDB 8YRG        8YRG   ? 4 ? 1  
5 UNP C562_ECOLX  P0ABE7 ? 5 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23 
6 UNP MRGX4_HUMAN Q96LA9 ? 5 
;DPTVPVFGTKLTPINGREETPCYNQTLSFTVLTCIISLVGLTGNAVVLWLLGYRMRRNAVSIYILNLAAADFLFLSFQII
RLPLRLINISHLIRKILVSVMTFPYFTGLSMLSAISTERCLSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLFSMLEWRFC
DFLFSGADSSWCETSDFIPVAWLIFLCVVLCVSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGILGALIYR
MHLNLEVLYCHVYLVCMSLSSLNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDKPEVDKGEGQLPEESLELSGSRLG
P
;
2  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8YRG B 1   ? 246 ? 8YRG   1  ? 246 ? 1    246 
2 2 8YRG C 20  ? 358 ? P62873 2  ? 340 ? 2    340 
3 3 8YRG D 1   ? 71  ? P59768 1  ? 71  ? 1    71  
4 4 8YRG E 1   ? 267 ? 8YRG   1  ? 255 ? 1    255 
5 5 8YRG R 35  ? 139 ? P0ABE7 23 ? 127 ? -115 -11 
6 6 8YRG R 152 ? 472 ? Q96LA9 2  ? 322 ? 2    322 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8YRG MET C 1   ? UNP P62873 ?   ?   'initiating methionine' -17  1  
2 8YRG HIS C 2   ? UNP P62873 ?   ?   'expression tag'        -16  2  
2 8YRG HIS C 3   ? UNP P62873 ?   ?   'expression tag'        -15  3  
2 8YRG HIS C 4   ? UNP P62873 ?   ?   'expression tag'        -14  4  
2 8YRG HIS C 5   ? UNP P62873 ?   ?   'expression tag'        -13  5  
2 8YRG HIS C 6   ? UNP P62873 ?   ?   'expression tag'        -12  6  
2 8YRG HIS C 7   ? UNP P62873 ?   ?   'expression tag'        -11  7  
2 8YRG LEU C 8   ? UNP P62873 ?   ?   'expression tag'        -10  8  
2 8YRG GLU C 9   ? UNP P62873 ?   ?   'expression tag'        -9   9  
2 8YRG VAL C 10  ? UNP P62873 ?   ?   'expression tag'        -8   10 
2 8YRG LEU C 11  ? UNP P62873 ?   ?   'expression tag'        -7   11 
2 8YRG PHE C 12  ? UNP P62873 ?   ?   'expression tag'        -6   12 
2 8YRG GLN C 13  ? UNP P62873 ?   ?   'expression tag'        -5   13 
2 8YRG GLY C 14  ? UNP P62873 ?   ?   'expression tag'        -4   14 
2 8YRG PRO C 15  ? UNP P62873 ?   ?   'expression tag'        -3   15 
2 8YRG GLY C 16  ? UNP P62873 ?   ?   'expression tag'        -2   16 
2 8YRG SER C 17  ? UNP P62873 ?   ?   'expression tag'        -1   17 
2 8YRG SER C 18  ? UNP P62873 ?   ?   'expression tag'        0    18 
2 8YRG GLY C 19  ? UNP P62873 ?   ?   'expression tag'        1    19 
5 8YRG ASP R 1   ? UNP P0ABE7 ?   ?   'expression tag'        -149 20 
5 8YRG TYR R 2   ? UNP P0ABE7 ?   ?   'expression tag'        -148 21 
5 8YRG LYS R 3   ? UNP P0ABE7 ?   ?   'expression tag'        -147 22 
5 8YRG ASP R 4   ? UNP P0ABE7 ?   ?   'expression tag'        -146 23 
5 8YRG ASP R 5   ? UNP P0ABE7 ?   ?   'expression tag'        -145 24 
5 8YRG ASP R 6   ? UNP P0ABE7 ?   ?   'expression tag'        -144 25 
5 8YRG ASP R 7   ? UNP P0ABE7 ?   ?   'expression tag'        -143 26 
5 8YRG ALA R 8   ? UNP P0ABE7 ?   ?   'expression tag'        -142 27 
5 8YRG LYS R 9   ? UNP P0ABE7 ?   ?   'expression tag'        -141 28 
5 8YRG LEU R 10  ? UNP P0ABE7 ?   ?   'expression tag'        -140 29 
5 8YRG GLN R 11  ? UNP P0ABE7 ?   ?   'expression tag'        -139 30 
5 8YRG THR R 12  ? UNP P0ABE7 ?   ?   'expression tag'        -138 31 
5 8YRG MET R 13  ? UNP P0ABE7 ?   ?   'expression tag'        -137 32 
5 8YRG HIS R 14  ? UNP P0ABE7 ?   ?   'expression tag'        -136 33 
5 8YRG HIS R 15  ? UNP P0ABE7 ?   ?   'expression tag'        -135 34 
5 8YRG HIS R 16  ? UNP P0ABE7 ?   ?   'expression tag'        -134 35 
5 8YRG HIS R 17  ? UNP P0ABE7 ?   ?   'expression tag'        -133 36 
5 8YRG HIS R 18  ? UNP P0ABE7 ?   ?   'expression tag'        -132 37 
5 8YRG HIS R 19  ? UNP P0ABE7 ?   ?   'expression tag'        -131 38 
5 8YRG HIS R 20  ? UNP P0ABE7 ?   ?   'expression tag'        -130 39 
5 8YRG HIS R 21  ? UNP P0ABE7 ?   ?   'expression tag'        -129 40 
5 8YRG HIS R 22  ? UNP P0ABE7 ?   ?   'expression tag'        -128 41 
5 8YRG HIS R 23  ? UNP P0ABE7 ?   ?   'expression tag'        -127 42 
5 8YRG GLU R 24  ? UNP P0ABE7 ?   ?   'expression tag'        -126 43 
5 8YRG ASN R 25  ? UNP P0ABE7 ?   ?   'expression tag'        -125 44 
5 8YRG LEU R 26  ? UNP P0ABE7 ?   ?   'expression tag'        -124 45 
5 8YRG TYR R 27  ? UNP P0ABE7 ?   ?   'expression tag'        -123 46 
5 8YRG PHE R 28  ? UNP P0ABE7 ?   ?   'expression tag'        -122 47 
5 8YRG GLN R 29  ? UNP P0ABE7 ?   ?   'expression tag'        -121 48 
5 8YRG GLY R 30  ? UNP P0ABE7 ?   ?   'expression tag'        -120 49 
5 8YRG GLY R 31  ? UNP P0ABE7 ?   ?   'expression tag'        -119 50 
5 8YRG THR R 32  ? UNP P0ABE7 ?   ?   'expression tag'        -118 51 
5 8YRG THR R 33  ? UNP P0ABE7 ?   ?   'expression tag'        -117 52 
5 8YRG MET R 34  ? UNP P0ABE7 ?   ?   'expression tag'        -116 53 
5 8YRG TRP R 41  ? UNP P0ABE7 MET 29  conflict                -109 54 
5 8YRG ILE R 136 ? UNP P0ABE7 HIS 124 conflict                -14  55 
5 8YRG LEU R 140 ? UNP P0ABE7 ?   ?   linker                  -10  56 
5 8YRG GLY R 141 ? UNP P0ABE7 ?   ?   linker                  -9   57 
5 8YRG SER R 142 ? UNP P0ABE7 ?   ?   linker                  -8   58 
5 8YRG THR R 143 ? UNP P0ABE7 ?   ?   linker                  -7   59 
5 8YRG LEU R 144 ? UNP P0ABE7 ?   ?   linker                  -6   60 
5 8YRG GLU R 145 ? UNP P0ABE7 ?   ?   linker                  -5   61 
5 8YRG VAL R 146 ? UNP P0ABE7 ?   ?   linker                  -4   62 
5 8YRG LEU R 147 ? UNP P0ABE7 ?   ?   linker                  -3   63 
5 8YRG PHE R 148 ? UNP P0ABE7 ?   ?   linker                  -2   64 
5 8YRG GLN R 149 ? UNP P0ABE7 ?   ?   linker                  -1   65 
5 8YRG GLY R 150 ? UNP P0ABE7 ?   ?   linker                  0    66 
5 8YRG PRO R 151 ? UNP P0ABE7 ?   ?   linker                  1    67 
6 8YRG SER R 233 ? UNP Q96LA9 LEU 83  variant                 83   68 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? ARG A 31  ? SER B 6   ARG B 31  1 ? 26 
HELX_P HELX_P2  AA2 LYS A 95  ? ASP A 102 ? LYS B 95  ASP B 102 5 ? 8  
HELX_P HELX_P3  AA3 ARG A 117 ? ASN A 130 ? ARG B 117 ASN B 130 1 ? 14 
HELX_P HELX_P4  AA4 ASN A 131 ? ARG A 135 ? ASN B 131 ARG B 135 5 ? 5  
HELX_P HELX_P5  AA5 LYS A 145 ? GLY A 156 ? LYS B 145 GLY B 156 1 ? 12 
HELX_P HELX_P6  AA6 LYS A 159 ? PHE A 164 ? LYS B 159 PHE B 164 1 ? 6  
HELX_P HELX_P7  AA7 PRO A 165 ? ALA A 168 ? PRO B 165 ALA B 168 5 ? 4  
HELX_P HELX_P8  AA8 ASP A 183 ? THR A 202 ? ASP B 183 THR B 202 1 ? 20 
HELX_P HELX_P9  AA9 ASN A 223 ? TYR A 243 ? ASN B 223 TYR B 243 1 ? 21 
HELX_P HELX_P10 AB1 LEU B 22  ? CYS B 43  ? LEU C 4   CYS C 25  1 ? 22 
HELX_P HELX_P11 AB2 THR B 47  ? ASN B 53  ? THR C 29  ASN C 35  1 ? 7  
HELX_P HELX_P12 AB3 ALA C 12  ? ASN C 24  ? ALA D 12  ASN D 24  1 ? 13 
HELX_P HELX_P13 AB4 LYS C 29  ? ALA C 43  ? LYS D 29  ALA D 43  1 ? 15 
HELX_P HELX_P14 AB5 ALA D 28  ? PHE D 32  ? ALA E 28  PHE E 32  5 ? 5  
HELX_P HELX_P15 AB6 SER D 53  ? GLY D 56  ? SER E 53  GLY E 56  5 ? 4  
HELX_P HELX_P16 AB7 ARG D 87  ? THR D 91  ? ARG E 87  THR E 91  5 ? 5  
HELX_P HELX_P17 AB8 THR E 177 ? ARG E 205 ? THR R 27  ARG R 55  1 ? 29 
HELX_P HELX_P18 AB9 VAL E 211 ? ARG E 236 ? VAL R 61  ARG R 86  1 ? 26 
HELX_P HELX_P19 AC1 SER E 241 ? TRP E 276 ? SER R 91  TRP R 126 1 ? 36 
HELX_P HELX_P20 AC2 TRP E 276 ? ARG E 283 ? TRP R 126 ARG R 133 1 ? 8  
HELX_P HELX_P21 AC3 HIS E 287 ? PHE E 303 ? HIS R 137 PHE R 153 1 ? 17 
HELX_P HELX_P22 AC4 PHE E 328 ? CYS E 354 ? PHE R 178 CYS R 204 1 ? 27 
HELX_P HELX_P23 AC5 PRO E 360 ? CYS E 378 ? PRO R 210 CYS R 228 1 ? 19 
HELX_P HELX_P24 AC6 GLY E 379 ? MET E 392 ? GLY R 229 MET R 242 1 ? 14 
HELX_P HELX_P25 AC7 ASN E 395 ? PHE E 424 ? ASN R 245 PHE R 274 1 ? 30 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 22  SG ? ? ? 1_555 D CYS 96  SG ? ? E CYS 22  E CYS 96  1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf2 disulf ? ? D CYS 159 SG ? ? ? 1_555 D CYS 229 SG ? ? E CYS 147 E CYS 217 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          D 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           E 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   D 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    E 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       4.63 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 2 ? 
AB3 ? 3 ? 
AB4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 69  ? VAL A 76  ? ILE B 69  VAL B 76  
AA1 2 VAL A 79  ? VAL A 86  ? VAL B 79  VAL B 86  
AA1 3 THR A 33  ? LEU A 39  ? THR B 33  LEU B 39  
AA1 4 ALA A 105 ? ASP A 111 ? ALA B 105 ASP B 111 
AA1 5 SER A 138 ? ASN A 144 ? SER B 138 ASN B 144 
AA1 6 CYS A 211 ? PHE A 215 ? CYS B 211 PHE B 215 
AA2 1 THR B 65  ? ARG B 70  ? THR C 47  ARG C 52  
AA2 2 PHE B 353 ? TRP B 357 ? PHE C 335 TRP C 339 
AA2 3 VAL B 345 ? SER B 349 ? VAL C 327 SER C 331 
AA2 4 VAL B 333 ? VAL B 338 ? VAL C 315 VAL C 320 
AA3 1 ILE B 76  ? TRP B 81  ? ILE C 58  TRP C 63  
AA3 2 LEU B 87  ? SER B 92  ? LEU C 69  SER C 74  
AA3 3 LYS B 96  ? ASP B 101 ? LYS C 78  ASP C 83  
AA3 4 LYS B 107 ? PRO B 112 ? LYS C 89  PRO C 94  
AA4 1 VAL B 118 ? TYR B 123 ? VAL C 100 TYR C 105 
AA4 2 TYR B 129 ? GLY B 134 ? TYR C 111 GLY C 116 
AA4 3 CYS B 139 ? ASN B 143 ? CYS C 121 ASN C 125 
AA4 4 ARG B 152 ? LEU B 157 ? ARG C 134 LEU C 139 
AA5 1 LEU B 164 ? ASP B 171 ? LEU C 146 ASP C 153 
AA5 2 GLN B 174 ? SER B 179 ? GLN C 156 SER C 161 
AA5 3 CYS B 184 ? TRP B 187 ? CYS C 166 TRP C 169 
AA5 4 GLN B 194 ? PHE B 198 ? GLN C 176 PHE C 180 
AA6 1 VAL B 205 ? LEU B 210 ? VAL C 187 LEU C 192 
AA6 2 LEU B 216 ? ALA B 221 ? LEU C 198 ALA C 203 
AA6 3 SER B 225 ? ASP B 230 ? SER C 207 ASP C 212 
AA6 4 CYS B 236 ? PHE B 240 ? CYS C 218 PHE C 222 
AA7 1 ILE B 247 ? PHE B 252 ? ILE C 229 PHE C 234 
AA7 2 ALA B 258 ? SER B 263 ? ALA C 240 SER C 245 
AA7 3 CYS B 268 ? ASP B 272 ? CYS C 250 ASP C 254 
AA7 4 GLN B 277 ? TYR B 282 ? GLN C 259 TYR C 264 
AA8 1 ILE B 291 ? PHE B 296 ? ILE C 273 PHE C 278 
AA8 2 LEU B 302 ? TYR B 307 ? LEU C 284 TYR C 289 
AA8 3 CYS B 312 ? ASP B 316 ? CYS C 294 ASP C 298 
AA8 4 ARG B 322 ? LEU B 326 ? ARG C 304 LEU C 308 
AA9 1 GLN D 3   ? SER D 7   ? GLN E 3   SER E 7   
AA9 2 LYS D 19  ? SER D 25  ? LYS E 19  SER E 25  
AA9 3 THR D 78  ? MET D 83  ? THR E 78  MET E 83  
AA9 4 PHE D 68  ? ASP D 73  ? PHE E 68  ASP E 73  
AB1 1 LEU D 11  ? VAL D 12  ? LEU E 11  VAL E 12  
AB1 2 TRP D 111 ? VAL D 119 ? TRP E 111 VAL E 119 
AB1 3 ALA D 92  ? SER D 99  ? ALA E 92  SER E 99  
AB1 4 GLY D 33  ? GLN D 39  ? GLY E 33  GLN E 39  
AB1 5 LEU D 45  ? ILE D 51  ? LEU E 45  ILE E 51  
AB1 6 ILE D 58  ? TYR D 60  ? ILE E 58  TYR E 60  
AB2 1 SER D 146 ? VAL D 147 ? SER E 134 VAL E 135 
AB2 2 LYS D 244 ? LEU D 245 ? LYS E 232 LEU E 233 
AB3 1 SER D 156 ? CYS D 159 ? SER E 144 CYS E 147 
AB3 2 ALA D 211 ? ILE D 216 ? ALA E 199 ILE E 204 
AB3 3 PHE D 203 ? SER D 208 ? PHE E 191 SER E 196 
AB4 1 ASN D 194 ? LEU D 195 ? ASN E 182 LEU E 183 
AB4 2 GLN D 186 ? TYR D 190 ? GLN E 174 TYR E 178 
AB4 3 LEU D 174 ? GLN D 179 ? LEU E 162 GLN E 167 
AB4 4 VAL D 226 ? GLN D 231 ? VAL E 214 GLN E 219 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 72  ? N THR B 72  O MET A 83  ? O MET B 83  
AA1 2 3 O HIS A 82  ? O HIS B 82  N LEU A 36  ? N LEU B 36  
AA1 3 4 N LEU A 39  ? N LEU B 39  O ILE A 107 ? O ILE B 107 
AA1 4 5 N PHE A 108 ? N PHE B 108 O PHE A 142 ? O PHE B 142 
AA1 5 6 N LEU A 141 ? N LEU B 141 O TYR A 212 ? O TYR B 212 
AA2 1 2 N ARG B 66  ? N ARG C 48  O ILE B 356 ? O ILE C 338 
AA2 2 3 O TRP B 357 ? O TRP C 339 N VAL B 345 ? N VAL C 327 
AA2 3 4 O ALA B 346 ? O ALA C 328 N GLY B 337 ? N GLY C 319 
AA3 1 2 N HIS B 80  ? N HIS C 62  O VAL B 89  ? O VAL C 71  
AA3 2 3 N LEU B 88  ? N LEU C 70  O TRP B 100 ? O TRP C 82  
AA3 3 4 N ILE B 99  ? N ILE C 81  O VAL B 108 ? O VAL C 90  
AA4 1 2 N MET B 119 ? N MET C 101 O GLY B 133 ? O GLY C 115 
AA4 2 3 N VAL B 130 ? N VAL C 112 O TYR B 142 ? O TYR C 124 
AA4 3 4 N ILE B 141 ? N ILE C 123 O SER B 154 ? O SER C 136 
AA5 1 2 N ARG B 168 ? N ARG C 150 O VAL B 176 ? O VAL C 158 
AA5 2 3 N THR B 177 ? N THR C 159 O ALA B 185 ? O ALA C 167 
AA5 3 4 N CYS B 184 ? N CYS C 166 O PHE B 198 ? O PHE C 180 
AA6 1 2 N SER B 209 ? N SER C 191 O VAL B 218 ? O VAL C 200 
AA6 2 3 N PHE B 217 ? N PHE C 199 O TRP B 229 ? O TRP C 211 
AA6 3 4 N ALA B 226 ? N ALA C 208 O PHE B 240 ? O PHE C 222 
AA7 1 2 N ALA B 249 ? N ALA C 231 O GLY B 262 ? O GLY C 244 
AA7 2 3 N PHE B 259 ? N PHE C 241 O PHE B 271 ? O PHE C 253 
AA7 3 4 N CYS B 268 ? N CYS C 250 O TYR B 282 ? O TYR C 264 
AA8 1 2 N THR B 292 ? N THR C 274 O GLY B 306 ? O GLY C 288 
AA8 2 3 N LEU B 303 ? N LEU C 285 O TRP B 315 ? O TRP C 297 
AA8 3 4 N CYS B 312 ? N CYS C 294 O LEU B 326 ? O LEU C 308 
AA9 1 2 N VAL D 5   ? N VAL E 5   O SER D 23  ? O SER E 23  
AA9 2 3 N LEU D 20  ? N LEU E 20  O LEU D 81  ? O LEU E 81  
AA9 3 4 O THR D 78  ? O THR E 78  N ASP D 73  ? N ASP E 73  
AB1 1 2 N VAL D 12  ? N VAL E 12  O THR D 118 ? O THR E 118 
AB1 2 3 O GLY D 112 ? O GLY E 112 N CYS D 96  ? N CYS E 96  
AB1 3 4 O TYR D 95  ? O TYR E 95  N VAL D 37  ? N VAL E 37  
AB1 4 5 N ARG D 38  ? N ARG E 38  O GLU D 46  ? O GLU E 46  
AB1 5 6 N TYR D 50  ? N TYR E 50  O TYR D 59  ? O TYR E 59  
AB2 1 2 N VAL D 147 ? N VAL E 135 O LYS D 244 ? O LYS E 232 
AB3 1 2 N ILE D 157 ? N ILE E 145 O LEU D 214 ? O LEU E 202 
AB3 2 3 O THR D 215 ? O THR E 203 N SER D 204 ? N SER E 192 
AB4 1 2 O ASN D 194 ? O ASN E 182 N TYR D 190 ? N TYR E 178 
AB4 2 3 O LEU D 188 ? O LEU E 176 N TRP D 176 ? N TRP E 164 
AB4 3 4 N TYR D 175 ? N TYR E 163 O MET D 230 ? O MET E 218 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OH  R TYR 106 ? ? O   R GLY 229 ? ? 2.09 
2 1 OG  C SER 74  ? ? OD1 C ASP 76  ? ? 2.10 
3 1 O   E ILE 100 ? ? OG  E SER 105 ? ? 2.15 
4 1 OE2 B GLU 8   ? ? OH  E TYR 163 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG B 32  ? ? -94.73  31.63   
2  1 ASN B 43  ? ? 39.41   41.75   
3  1 THR B 48  ? ? -99.94  36.86   
4  1 PHE B 100 ? ? -90.82  52.81   
5  1 ASN B 130 ? ? -96.30  32.44   
6  1 ASP B 206 ? ? 59.27   18.45   
7  1 TYR B 243 ? ? -93.23  45.77   
8  1 ASN B 244 ? ? 51.39   14.49   
9  1 THR C 34  ? ? -69.73  0.98    
10 1 THR C 87  ? ? 74.28   -4.84   
11 1 ARG C 129 ? ? -78.30  -165.21 
12 1 GLU C 130 ? ? 55.90   7.75    
13 1 ASP C 153 ? ? -161.12 -168.42 
14 1 SER C 334 ? ? 71.27   37.06   
15 1 GLN E 113 ? ? -78.35  -165.99 
16 1 SER E 134 ? ? -160.12 118.64  
17 1 SER E 150 ? ? -94.32  -60.06  
18 1 MET E 180 ? ? 74.94   -11.85  
19 1 SER E 181 ? ? -141.29 -13.30  
20 1 ALA E 199 ? ? -162.48 117.98  
21 1 ASN R 59  ? ? -101.00 -168.53 
22 1 CYS R 132 ? ? -130.25 -37.98  
23 1 GLU R 157 ? ? -148.55 -157.43 
24 1 TRP R 158 ? ? -67.73  67.25   
25 1 CYS R 204 ? ? -90.16  52.36   
26 1 HIS R 243 ? ? -104.34 40.22   
# 
_pdbx_entry_details.entry_id                 8YRG 
_pdbx_entry_details.has_ligand_of_interest   Y 
_pdbx_entry_details.compound_details         ? 
_pdbx_entry_details.source_details           ? 
_pdbx_entry_details.nonpolymer_details       ? 
_pdbx_entry_details.sequence_details         ? 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8YRG 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8YRG 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.14 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               375325 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'fospropofol-bound MRGPRX4-Gq complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8YRG 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             200 
_em_imaging.nominal_defocus_max             28000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8YRG 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE-PROPANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8YRG 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B MET 1    ? A MET 1   
2   1 Y 1 B GLY 2    ? A GLY 2   
3   1 Y 1 B SER 3    ? A SER 3   
4   1 Y 1 B GLN 52   ? A GLN 52  
5   1 Y 1 B MET 53   ? A MET 53  
6   1 Y 1 B ARG 54   ? A ARG 54  
7   1 Y 1 B ILE 55   ? A ILE 55  
8   1 Y 1 B LEU 56   ? A LEU 56  
9   1 Y 1 B HIS 57   ? A HIS 57  
10  1 Y 1 B GLY 58   ? A GLY 58  
11  1 Y 1 B GLY 59   ? A GLY 59  
12  1 Y 1 B SER 60   ? A SER 60  
13  1 Y 1 B GLY 61   ? A GLY 61  
14  1 Y 1 B GLY 62   ? A GLY 62  
15  1 Y 1 B SER 63   ? A SER 63  
16  1 Y 1 B GLY 64   ? A GLY 64  
17  1 Y 1 B GLY 65   ? A GLY 65  
18  1 Y 1 B THR 66   ? A THR 66  
19  1 Y 1 B SER 67   ? A SER 67  
20  1 Y 1 B GLY 88   ? A GLY 88  
21  1 Y 1 B GLN 89   ? A GLN 89  
22  1 Y 1 B ARG 90   ? A ARG 90  
23  1 Y 1 B ASP 91   ? A ASP 91  
24  1 Y 1 B GLU 92   ? A GLU 92  
25  1 Y 1 C MET -17  ? B MET 1   
26  1 Y 1 C HIS -16  ? B HIS 2   
27  1 Y 1 C HIS -15  ? B HIS 3   
28  1 Y 1 C HIS -14  ? B HIS 4   
29  1 Y 1 C HIS -13  ? B HIS 5   
30  1 Y 1 C HIS -12  ? B HIS 6   
31  1 Y 1 C HIS -11  ? B HIS 7   
32  1 Y 1 C LEU -10  ? B LEU 8   
33  1 Y 1 C GLU -9   ? B GLU 9   
34  1 Y 1 C VAL -8   ? B VAL 10  
35  1 Y 1 C LEU -7   ? B LEU 11  
36  1 Y 1 C PHE -6   ? B PHE 12  
37  1 Y 1 C GLN -5   ? B GLN 13  
38  1 Y 1 C GLY -4   ? B GLY 14  
39  1 Y 1 C PRO -3   ? B PRO 15  
40  1 Y 1 C GLY -2   ? B GLY 16  
41  1 Y 1 C SER -1   ? B SER 17  
42  1 Y 1 C SER 0    ? B SER 18  
43  1 Y 1 C GLY 1    ? B GLY 19  
44  1 Y 1 C SER 2    ? B SER 20  
45  1 Y 1 D MET 1    ? C MET 1   
46  1 Y 1 D ALA 2    ? C ALA 2   
47  1 Y 1 D SER 3    ? C SER 3   
48  1 Y 1 D ASN 4    ? C ASN 4   
49  1 Y 1 D ASN 5    ? C ASN 5   
50  1 Y 1 D THR 6    ? C THR 6   
51  1 Y 1 D ALA 7    ? C ALA 7   
52  1 Y 1 D SER 8    ? C SER 8   
53  1 Y 1 D ILE 9    ? C ILE 9   
54  1 Y 1 D ALA 10   ? C ALA 10  
55  1 Y 1 D ARG 62   ? C ARG 62  
56  1 Y 1 D GLU 63   ? C GLU 63  
57  1 Y 1 D LYS 64   ? C LYS 64  
58  1 Y 1 D LYS 65   ? C LYS 65  
59  1 Y 1 D PHE 66   ? C PHE 66  
60  1 Y 1 D PHE 67   ? C PHE 67  
61  1 Y 1 D CYS 68   ? C CYS 68  
62  1 Y 1 D ALA 69   ? C ALA 69  
63  1 Y 1 D ILE 70   ? C ILE 70  
64  1 Y 1 D LEU 71   ? C LEU 71  
65  1 Y 1 E ASP 1    ? D ASP 1   
66  1 Y 1 E SER 120  A D SER 121 
67  1 Y 1 E GLY 120  B D GLY 122 
68  1 Y 1 E GLY 120  C D GLY 123 
69  1 Y 1 E GLY 120  D D GLY 124 
70  1 Y 1 E GLY 120  E D GLY 125 
71  1 Y 1 E SER 120  F D SER 126 
72  1 Y 1 E GLY 120  G D GLY 127 
73  1 Y 1 E GLY 120  H D GLY 128 
74  1 Y 1 E GLY 120  I D GLY 129 
75  1 Y 1 E GLY 120  J D GLY 130 
76  1 Y 1 E SER 120  K D SER 131 
77  1 Y 1 E GLY 120  L D GLY 132 
78  1 Y 1 E GLY 120  M D GLY 133 
79  1 Y 1 E GLY 120  N D GLY 134 
80  1 Y 1 E GLY 120  O D GLY 135 
81  1 Y 1 E LYS 236  ? D LYS 248 
82  1 Y 1 E ALA 237  ? D ALA 249 
83  1 Y 1 E ALA 238  ? D ALA 250 
84  1 Y 1 E ALA 239  ? D ALA 251 
85  1 Y 1 E LEU 240  ? D LEU 252 
86  1 Y 1 E GLU 241  ? D GLU 253 
87  1 Y 1 E VAL 242  ? D VAL 254 
88  1 Y 1 E LEU 243  ? D LEU 255 
89  1 Y 1 E PHE 244  ? D PHE 256 
90  1 Y 1 E GLN 245  ? D GLN 257 
91  1 Y 1 E GLY 246  ? D GLY 258 
92  1 Y 1 E PRO 247  ? D PRO 259 
93  1 Y 1 E HIS 248  ? D HIS 260 
94  1 Y 1 E HIS 249  ? D HIS 261 
95  1 Y 1 E HIS 250  ? D HIS 262 
96  1 Y 1 E HIS 251  ? D HIS 263 
97  1 Y 1 E HIS 252  ? D HIS 264 
98  1 Y 1 E HIS 253  ? D HIS 265 
99  1 Y 1 E HIS 254  ? D HIS 266 
100 1 Y 1 E HIS 255  ? D HIS 267 
101 1 Y 1 R ASP -149 ? E ASP 1   
102 1 Y 1 R TYR -148 ? E TYR 2   
103 1 Y 1 R LYS -147 ? E LYS 3   
104 1 Y 1 R ASP -146 ? E ASP 4   
105 1 Y 1 R ASP -145 ? E ASP 5   
106 1 Y 1 R ASP -144 ? E ASP 6   
107 1 Y 1 R ASP -143 ? E ASP 7   
108 1 Y 1 R ALA -142 ? E ALA 8   
109 1 Y 1 R LYS -141 ? E LYS 9   
110 1 Y 1 R LEU -140 ? E LEU 10  
111 1 Y 1 R GLN -139 ? E GLN 11  
112 1 Y 1 R THR -138 ? E THR 12  
113 1 Y 1 R MET -137 ? E MET 13  
114 1 Y 1 R HIS -136 ? E HIS 14  
115 1 Y 1 R HIS -135 ? E HIS 15  
116 1 Y 1 R HIS -134 ? E HIS 16  
117 1 Y 1 R HIS -133 ? E HIS 17  
118 1 Y 1 R HIS -132 ? E HIS 18  
119 1 Y 1 R HIS -131 ? E HIS 19  
120 1 Y 1 R HIS -130 ? E HIS 20  
121 1 Y 1 R HIS -129 ? E HIS 21  
122 1 Y 1 R HIS -128 ? E HIS 22  
123 1 Y 1 R HIS -127 ? E HIS 23  
124 1 Y 1 R GLU -126 ? E GLU 24  
125 1 Y 1 R ASN -125 ? E ASN 25  
126 1 Y 1 R LEU -124 ? E LEU 26  
127 1 Y 1 R TYR -123 ? E TYR 27  
128 1 Y 1 R PHE -122 ? E PHE 28  
129 1 Y 1 R GLN -121 ? E GLN 29  
130 1 Y 1 R GLY -120 ? E GLY 30  
131 1 Y 1 R GLY -119 ? E GLY 31  
132 1 Y 1 R THR -118 ? E THR 32  
133 1 Y 1 R THR -117 ? E THR 33  
134 1 Y 1 R MET -116 ? E MET 34  
135 1 Y 1 R ALA -115 ? E ALA 35  
136 1 Y 1 R ASP -114 ? E ASP 36  
137 1 Y 1 R LEU -113 ? E LEU 37  
138 1 Y 1 R GLU -112 ? E GLU 38  
139 1 Y 1 R ASP -111 ? E ASP 39  
140 1 Y 1 R ASN -110 ? E ASN 40  
141 1 Y 1 R TRP -109 ? E TRP 41  
142 1 Y 1 R GLU -108 ? E GLU 42  
143 1 Y 1 R THR -107 ? E THR 43  
144 1 Y 1 R LEU -106 ? E LEU 44  
145 1 Y 1 R ASN -105 ? E ASN 45  
146 1 Y 1 R ASP -104 ? E ASP 46  
147 1 Y 1 R ASN -103 ? E ASN 47  
148 1 Y 1 R LEU -102 ? E LEU 48  
149 1 Y 1 R LYS -101 ? E LYS 49  
150 1 Y 1 R VAL -100 ? E VAL 50  
151 1 Y 1 R ILE -99  ? E ILE 51  
152 1 Y 1 R GLU -98  ? E GLU 52  
153 1 Y 1 R LYS -97  ? E LYS 53  
154 1 Y 1 R ALA -96  ? E ALA 54  
155 1 Y 1 R ASP -95  ? E ASP 55  
156 1 Y 1 R ASN -94  ? E ASN 56  
157 1 Y 1 R ALA -93  ? E ALA 57  
158 1 Y 1 R ALA -92  ? E ALA 58  
159 1 Y 1 R GLN -91  ? E GLN 59  
160 1 Y 1 R VAL -90  ? E VAL 60  
161 1 Y 1 R LYS -89  ? E LYS 61  
162 1 Y 1 R ASP -88  ? E ASP 62  
163 1 Y 1 R ALA -87  ? E ALA 63  
164 1 Y 1 R LEU -86  ? E LEU 64  
165 1 Y 1 R THR -85  ? E THR 65  
166 1 Y 1 R LYS -84  ? E LYS 66  
167 1 Y 1 R MET -83  ? E MET 67  
168 1 Y 1 R ARG -82  ? E ARG 68  
169 1 Y 1 R ALA -81  ? E ALA 69  
170 1 Y 1 R ALA -80  ? E ALA 70  
171 1 Y 1 R ALA -79  ? E ALA 71  
172 1 Y 1 R LEU -78  ? E LEU 72  
173 1 Y 1 R ASP -77  ? E ASP 73  
174 1 Y 1 R ALA -76  ? E ALA 74  
175 1 Y 1 R GLN -75  ? E GLN 75  
176 1 Y 1 R LYS -74  ? E LYS 76  
177 1 Y 1 R ALA -73  ? E ALA 77  
178 1 Y 1 R THR -72  ? E THR 78  
179 1 Y 1 R PRO -71  ? E PRO 79  
180 1 Y 1 R PRO -70  ? E PRO 80  
181 1 Y 1 R LYS -69  ? E LYS 81  
182 1 Y 1 R LEU -68  ? E LEU 82  
183 1 Y 1 R GLU -67  ? E GLU 83  
184 1 Y 1 R ASP -66  ? E ASP 84  
185 1 Y 1 R LYS -65  ? E LYS 85  
186 1 Y 1 R SER -64  ? E SER 86  
187 1 Y 1 R PRO -63  ? E PRO 87  
188 1 Y 1 R ASP -62  ? E ASP 88  
189 1 Y 1 R SER -61  ? E SER 89  
190 1 Y 1 R PRO -60  ? E PRO 90  
191 1 Y 1 R GLU -59  ? E GLU 91  
192 1 Y 1 R MET -58  ? E MET 92  
193 1 Y 1 R LYS -57  ? E LYS 93  
194 1 Y 1 R ASP -56  ? E ASP 94  
195 1 Y 1 R PHE -55  ? E PHE 95  
196 1 Y 1 R ARG -54  ? E ARG 96  
197 1 Y 1 R HIS -53  ? E HIS 97  
198 1 Y 1 R GLY -52  ? E GLY 98  
199 1 Y 1 R PHE -51  ? E PHE 99  
200 1 Y 1 R ASP -50  ? E ASP 100 
201 1 Y 1 R ILE -49  ? E ILE 101 
202 1 Y 1 R LEU -48  ? E LEU 102 
203 1 Y 1 R VAL -47  ? E VAL 103 
204 1 Y 1 R GLY -46  ? E GLY 104 
205 1 Y 1 R GLN -45  ? E GLN 105 
206 1 Y 1 R ILE -44  ? E ILE 106 
207 1 Y 1 R ASP -43  ? E ASP 107 
208 1 Y 1 R ASP -42  ? E ASP 108 
209 1 Y 1 R ALA -41  ? E ALA 109 
210 1 Y 1 R LEU -40  ? E LEU 110 
211 1 Y 1 R LYS -39  ? E LYS 111 
212 1 Y 1 R LEU -38  ? E LEU 112 
213 1 Y 1 R ALA -37  ? E ALA 113 
214 1 Y 1 R ASN -36  ? E ASN 114 
215 1 Y 1 R GLU -35  ? E GLU 115 
216 1 Y 1 R GLY -34  ? E GLY 116 
217 1 Y 1 R LYS -33  ? E LYS 117 
218 1 Y 1 R VAL -32  ? E VAL 118 
219 1 Y 1 R LYS -31  ? E LYS 119 
220 1 Y 1 R GLU -30  ? E GLU 120 
221 1 Y 1 R ALA -29  ? E ALA 121 
222 1 Y 1 R GLN -28  ? E GLN 122 
223 1 Y 1 R ALA -27  ? E ALA 123 
224 1 Y 1 R ALA -26  ? E ALA 124 
225 1 Y 1 R ALA -25  ? E ALA 125 
226 1 Y 1 R GLU -24  ? E GLU 126 
227 1 Y 1 R GLN -23  ? E GLN 127 
228 1 Y 1 R LEU -22  ? E LEU 128 
229 1 Y 1 R LYS -21  ? E LYS 129 
230 1 Y 1 R THR -20  ? E THR 130 
231 1 Y 1 R THR -19  ? E THR 131 
232 1 Y 1 R ARG -18  ? E ARG 132 
233 1 Y 1 R ASN -17  ? E ASN 133 
234 1 Y 1 R ALA -16  ? E ALA 134 
235 1 Y 1 R TYR -15  ? E TYR 135 
236 1 Y 1 R ILE -14  ? E ILE 136 
237 1 Y 1 R GLN -13  ? E GLN 137 
238 1 Y 1 R LYS -12  ? E LYS 138 
239 1 Y 1 R TYR -11  ? E TYR 139 
240 1 Y 1 R LEU -10  ? E LEU 140 
241 1 Y 1 R GLY -9   ? E GLY 141 
242 1 Y 1 R SER -8   ? E SER 142 
243 1 Y 1 R THR -7   ? E THR 143 
244 1 Y 1 R LEU -6   ? E LEU 144 
245 1 Y 1 R GLU -5   ? E GLU 145 
246 1 Y 1 R VAL -4   ? E VAL 146 
247 1 Y 1 R LEU -3   ? E LEU 147 
248 1 Y 1 R PHE -2   ? E PHE 148 
249 1 Y 1 R GLN -1   ? E GLN 149 
250 1 Y 1 R GLY 0    ? E GLY 150 
251 1 Y 1 R PRO 1    ? E PRO 151 
252 1 Y 1 R ASP 2    ? E ASP 152 
253 1 Y 1 R PRO 3    ? E PRO 153 
254 1 Y 1 R THR 4    ? E THR 154 
255 1 Y 1 R VAL 5    ? E VAL 155 
256 1 Y 1 R PRO 6    ? E PRO 156 
257 1 Y 1 R VAL 7    ? E VAL 157 
258 1 Y 1 R PHE 8    ? E PHE 158 
259 1 Y 1 R GLY 9    ? E GLY 159 
260 1 Y 1 R THR 10   ? E THR 160 
261 1 Y 1 R LYS 11   ? E LYS 161 
262 1 Y 1 R LEU 12   ? E LEU 162 
263 1 Y 1 R THR 13   ? E THR 163 
264 1 Y 1 R PRO 14   ? E PRO 164 
265 1 Y 1 R ILE 15   ? E ILE 165 
266 1 Y 1 R ASN 16   ? E ASN 166 
267 1 Y 1 R GLY 17   ? E GLY 167 
268 1 Y 1 R ARG 18   ? E ARG 168 
269 1 Y 1 R GLU 19   ? E GLU 169 
270 1 Y 1 R GLU 20   ? E GLU 170 
271 1 Y 1 R THR 21   ? E THR 171 
272 1 Y 1 R PRO 22   ? E PRO 172 
273 1 Y 1 R CYS 23   ? E CYS 173 
274 1 Y 1 R TYR 24   ? E TYR 174 
275 1 Y 1 R ASN 25   ? E ASN 175 
276 1 Y 1 R CYS 161  ? E CYS 311 
277 1 Y 1 R ASP 162  ? E ASP 312 
278 1 Y 1 R PHE 163  ? E PHE 313 
279 1 Y 1 R LEU 164  ? E LEU 314 
280 1 Y 1 R PHE 165  ? E PHE 315 
281 1 Y 1 R SER 166  ? E SER 316 
282 1 Y 1 R GLY 167  ? E GLY 317 
283 1 Y 1 R ALA 168  ? E ALA 318 
284 1 Y 1 R ASP 169  ? E ASP 319 
285 1 Y 1 R SER 170  ? E SER 320 
286 1 Y 1 R SER 171  ? E SER 321 
287 1 Y 1 R TRP 172  ? E TRP 322 
288 1 Y 1 R CYS 173  ? E CYS 323 
289 1 Y 1 R GLU 174  ? E GLU 324 
290 1 Y 1 R SER 277  ? E SER 427 
291 1 Y 1 R PHE 278  ? E PHE 428 
292 1 Y 1 R ARG 279  ? E ARG 429 
293 1 Y 1 R GLN 280  ? E GLN 430 
294 1 Y 1 R ARG 281  ? E ARG 431 
295 1 Y 1 R GLN 282  ? E GLN 432 
296 1 Y 1 R ASN 283  ? E ASN 433 
297 1 Y 1 R ARG 284  ? E ARG 434 
298 1 Y 1 R GLN 285  ? E GLN 435 
299 1 Y 1 R ASN 286  ? E ASN 436 
300 1 Y 1 R LEU 287  ? E LEU 437 
301 1 Y 1 R LYS 288  ? E LYS 438 
302 1 Y 1 R LEU 289  ? E LEU 439 
303 1 Y 1 R VAL 290  ? E VAL 440 
304 1 Y 1 R LEU 291  ? E LEU 441 
305 1 Y 1 R GLN 292  ? E GLN 442 
306 1 Y 1 R ARG 293  ? E ARG 443 
307 1 Y 1 R ALA 294  ? E ALA 444 
308 1 Y 1 R LEU 295  ? E LEU 445 
309 1 Y 1 R GLN 296  ? E GLN 446 
310 1 Y 1 R ASP 297  ? E ASP 447 
311 1 Y 1 R LYS 298  ? E LYS 448 
312 1 Y 1 R PRO 299  ? E PRO 449 
313 1 Y 1 R GLU 300  ? E GLU 450 
314 1 Y 1 R VAL 301  ? E VAL 451 
315 1 Y 1 R ASP 302  ? E ASP 452 
316 1 Y 1 R LYS 303  ? E LYS 453 
317 1 Y 1 R GLY 304  ? E GLY 454 
318 1 Y 1 R GLU 305  ? E GLU 455 
319 1 Y 1 R GLY 306  ? E GLY 456 
320 1 Y 1 R GLN 307  ? E GLN 457 
321 1 Y 1 R LEU 308  ? E LEU 458 
322 1 Y 1 R PRO 309  ? E PRO 459 
323 1 Y 1 R GLU 310  ? E GLU 460 
324 1 Y 1 R GLU 311  ? E GLU 461 
325 1 Y 1 R SER 312  ? E SER 462 
326 1 Y 1 R LEU 313  ? E LEU 463 
327 1 Y 1 R GLU 314  ? E GLU 464 
328 1 Y 1 R LEU 315  ? E LEU 465 
329 1 Y 1 R SER 316  ? E SER 466 
330 1 Y 1 R GLY 317  ? E GLY 467 
331 1 Y 1 R SER 318  ? E SER 468 
332 1 Y 1 R ARG 319  ? E ARG 469 
333 1 Y 1 R LEU 320  ? E LEU 470 
334 1 Y 1 R GLY 321  ? E GLY 471 
335 1 Y 1 R PRO 322  ? E PRO 472 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1LZU C1   C N N 1   
A1LZU C10  C N N 2   
A1LZU C11  C N N 3   
A1LZU C12  C N N 4   
A1LZU C13  C N N 5   
A1LZU C2   C N N 6   
A1LZU C3   C N N 7   
A1LZU C4   C Y N 8   
A1LZU C5   C Y N 9   
A1LZU C6   C Y N 10  
A1LZU C7   C Y N 11  
A1LZU C8   C Y N 12  
A1LZU C9   C Y N 13  
A1LZU O1   O N N 14  
A1LZU O2   O N N 15  
A1LZU O3   O N N 16  
A1LZU O4   O N N 17  
A1LZU O5   O N N 18  
A1LZU P1   P N N 19  
A1LZU H1   H N N 20  
A1LZU H2   H N N 21  
A1LZU H3   H N N 22  
A1LZU H4   H N N 23  
A1LZU H5   H N N 24  
A1LZU H6   H N N 25  
A1LZU H7   H N N 26  
A1LZU H8   H N N 27  
A1LZU H9   H N N 28  
A1LZU H10  H N N 29  
A1LZU H11  H N N 30  
A1LZU H12  H N N 31  
A1LZU H13  H N N 32  
A1LZU H14  H N N 33  
A1LZU H15  H N N 34  
A1LZU H16  H N N 35  
A1LZU H17  H N N 36  
A1LZU H18  H N N 37  
A1LZU H19  H N N 38  
A1LZU H20  H N N 39  
A1LZU H21  H N N 40  
ALA   N    N N N 41  
ALA   CA   C N S 42  
ALA   C    C N N 43  
ALA   O    O N N 44  
ALA   CB   C N N 45  
ALA   OXT  O N N 46  
ALA   H    H N N 47  
ALA   H2   H N N 48  
ALA   HA   H N N 49  
ALA   HB1  H N N 50  
ALA   HB2  H N N 51  
ALA   HB3  H N N 52  
ALA   HXT  H N N 53  
ARG   N    N N N 54  
ARG   CA   C N S 55  
ARG   C    C N N 56  
ARG   O    O N N 57  
ARG   CB   C N N 58  
ARG   CG   C N N 59  
ARG   CD   C N N 60  
ARG   NE   N N N 61  
ARG   CZ   C N N 62  
ARG   NH1  N N N 63  
ARG   NH2  N N N 64  
ARG   OXT  O N N 65  
ARG   H    H N N 66  
ARG   H2   H N N 67  
ARG   HA   H N N 68  
ARG   HB2  H N N 69  
ARG   HB3  H N N 70  
ARG   HG2  H N N 71  
ARG   HG3  H N N 72  
ARG   HD2  H N N 73  
ARG   HD3  H N N 74  
ARG   HE   H N N 75  
ARG   HH11 H N N 76  
ARG   HH12 H N N 77  
ARG   HH21 H N N 78  
ARG   HH22 H N N 79  
ARG   HXT  H N N 80  
ASN   N    N N N 81  
ASN   CA   C N S 82  
ASN   C    C N N 83  
ASN   O    O N N 84  
ASN   CB   C N N 85  
ASN   CG   C N N 86  
ASN   OD1  O N N 87  
ASN   ND2  N N N 88  
ASN   OXT  O N N 89  
ASN   H    H N N 90  
ASN   H2   H N N 91  
ASN   HA   H N N 92  
ASN   HB2  H N N 93  
ASN   HB3  H N N 94  
ASN   HD21 H N N 95  
ASN   HD22 H N N 96  
ASN   HXT  H N N 97  
ASP   N    N N N 98  
ASP   CA   C N S 99  
ASP   C    C N N 100 
ASP   O    O N N 101 
ASP   CB   C N N 102 
ASP   CG   C N N 103 
ASP   OD1  O N N 104 
ASP   OD2  O N N 105 
ASP   OXT  O N N 106 
ASP   H    H N N 107 
ASP   H2   H N N 108 
ASP   HA   H N N 109 
ASP   HB2  H N N 110 
ASP   HB3  H N N 111 
ASP   HD2  H N N 112 
ASP   HXT  H N N 113 
CYS   N    N N N 114 
CYS   CA   C N R 115 
CYS   C    C N N 116 
CYS   O    O N N 117 
CYS   CB   C N N 118 
CYS   SG   S N N 119 
CYS   OXT  O N N 120 
CYS   H    H N N 121 
CYS   H2   H N N 122 
CYS   HA   H N N 123 
CYS   HB2  H N N 124 
CYS   HB3  H N N 125 
CYS   HG   H N N 126 
CYS   HXT  H N N 127 
GLN   N    N N N 128 
GLN   CA   C N S 129 
GLN   C    C N N 130 
GLN   O    O N N 131 
GLN   CB   C N N 132 
GLN   CG   C N N 133 
GLN   CD   C N N 134 
GLN   OE1  O N N 135 
GLN   NE2  N N N 136 
GLN   OXT  O N N 137 
GLN   H    H N N 138 
GLN   H2   H N N 139 
GLN   HA   H N N 140 
GLN   HB2  H N N 141 
GLN   HB3  H N N 142 
GLN   HG2  H N N 143 
GLN   HG3  H N N 144 
GLN   HE21 H N N 145 
GLN   HE22 H N N 146 
GLN   HXT  H N N 147 
GLU   N    N N N 148 
GLU   CA   C N S 149 
GLU   C    C N N 150 
GLU   O    O N N 151 
GLU   CB   C N N 152 
GLU   CG   C N N 153 
GLU   CD   C N N 154 
GLU   OE1  O N N 155 
GLU   OE2  O N N 156 
GLU   OXT  O N N 157 
GLU   H    H N N 158 
GLU   H2   H N N 159 
GLU   HA   H N N 160 
GLU   HB2  H N N 161 
GLU   HB3  H N N 162 
GLU   HG2  H N N 163 
GLU   HG3  H N N 164 
GLU   HE2  H N N 165 
GLU   HXT  H N N 166 
GLY   N    N N N 167 
GLY   CA   C N N 168 
GLY   C    C N N 169 
GLY   O    O N N 170 
GLY   OXT  O N N 171 
GLY   H    H N N 172 
GLY   H2   H N N 173 
GLY   HA2  H N N 174 
GLY   HA3  H N N 175 
GLY   HXT  H N N 176 
HIS   N    N N N 177 
HIS   CA   C N S 178 
HIS   C    C N N 179 
HIS   O    O N N 180 
HIS   CB   C N N 181 
HIS   CG   C Y N 182 
HIS   ND1  N Y N 183 
HIS   CD2  C Y N 184 
HIS   CE1  C Y N 185 
HIS   NE2  N Y N 186 
HIS   OXT  O N N 187 
HIS   H    H N N 188 
HIS   H2   H N N 189 
HIS   HA   H N N 190 
HIS   HB2  H N N 191 
HIS   HB3  H N N 192 
HIS   HD1  H N N 193 
HIS   HD2  H N N 194 
HIS   HE1  H N N 195 
HIS   HE2  H N N 196 
HIS   HXT  H N N 197 
ILE   N    N N N 198 
ILE   CA   C N S 199 
ILE   C    C N N 200 
ILE   O    O N N 201 
ILE   CB   C N S 202 
ILE   CG1  C N N 203 
ILE   CG2  C N N 204 
ILE   CD1  C N N 205 
ILE   OXT  O N N 206 
ILE   H    H N N 207 
ILE   H2   H N N 208 
ILE   HA   H N N 209 
ILE   HB   H N N 210 
ILE   HG12 H N N 211 
ILE   HG13 H N N 212 
ILE   HG21 H N N 213 
ILE   HG22 H N N 214 
ILE   HG23 H N N 215 
ILE   HD11 H N N 216 
ILE   HD12 H N N 217 
ILE   HD13 H N N 218 
ILE   HXT  H N N 219 
LEU   N    N N N 220 
LEU   CA   C N S 221 
LEU   C    C N N 222 
LEU   O    O N N 223 
LEU   CB   C N N 224 
LEU   CG   C N N 225 
LEU   CD1  C N N 226 
LEU   CD2  C N N 227 
LEU   OXT  O N N 228 
LEU   H    H N N 229 
LEU   H2   H N N 230 
LEU   HA   H N N 231 
LEU   HB2  H N N 232 
LEU   HB3  H N N 233 
LEU   HG   H N N 234 
LEU   HD11 H N N 235 
LEU   HD12 H N N 236 
LEU   HD13 H N N 237 
LEU   HD21 H N N 238 
LEU   HD22 H N N 239 
LEU   HD23 H N N 240 
LEU   HXT  H N N 241 
LYS   N    N N N 242 
LYS   CA   C N S 243 
LYS   C    C N N 244 
LYS   O    O N N 245 
LYS   CB   C N N 246 
LYS   CG   C N N 247 
LYS   CD   C N N 248 
LYS   CE   C N N 249 
LYS   NZ   N N N 250 
LYS   OXT  O N N 251 
LYS   H    H N N 252 
LYS   H2   H N N 253 
LYS   HA   H N N 254 
LYS   HB2  H N N 255 
LYS   HB3  H N N 256 
LYS   HG2  H N N 257 
LYS   HG3  H N N 258 
LYS   HD2  H N N 259 
LYS   HD3  H N N 260 
LYS   HE2  H N N 261 
LYS   HE3  H N N 262 
LYS   HZ1  H N N 263 
LYS   HZ2  H N N 264 
LYS   HZ3  H N N 265 
LYS   HXT  H N N 266 
MET   N    N N N 267 
MET   CA   C N S 268 
MET   C    C N N 269 
MET   O    O N N 270 
MET   CB   C N N 271 
MET   CG   C N N 272 
MET   SD   S N N 273 
MET   CE   C N N 274 
MET   OXT  O N N 275 
MET   H    H N N 276 
MET   H2   H N N 277 
MET   HA   H N N 278 
MET   HB2  H N N 279 
MET   HB3  H N N 280 
MET   HG2  H N N 281 
MET   HG3  H N N 282 
MET   HE1  H N N 283 
MET   HE2  H N N 284 
MET   HE3  H N N 285 
MET   HXT  H N N 286 
PHE   N    N N N 287 
PHE   CA   C N S 288 
PHE   C    C N N 289 
PHE   O    O N N 290 
PHE   CB   C N N 291 
PHE   CG   C Y N 292 
PHE   CD1  C Y N 293 
PHE   CD2  C Y N 294 
PHE   CE1  C Y N 295 
PHE   CE2  C Y N 296 
PHE   CZ   C Y N 297 
PHE   OXT  O N N 298 
PHE   H    H N N 299 
PHE   H2   H N N 300 
PHE   HA   H N N 301 
PHE   HB2  H N N 302 
PHE   HB3  H N N 303 
PHE   HD1  H N N 304 
PHE   HD2  H N N 305 
PHE   HE1  H N N 306 
PHE   HE2  H N N 307 
PHE   HZ   H N N 308 
PHE   HXT  H N N 309 
PRO   N    N N N 310 
PRO   CA   C N S 311 
PRO   C    C N N 312 
PRO   O    O N N 313 
PRO   CB   C N N 314 
PRO   CG   C N N 315 
PRO   CD   C N N 316 
PRO   OXT  O N N 317 
PRO   H    H N N 318 
PRO   HA   H N N 319 
PRO   HB2  H N N 320 
PRO   HB3  H N N 321 
PRO   HG2  H N N 322 
PRO   HG3  H N N 323 
PRO   HD2  H N N 324 
PRO   HD3  H N N 325 
PRO   HXT  H N N 326 
SER   N    N N N 327 
SER   CA   C N S 328 
SER   C    C N N 329 
SER   O    O N N 330 
SER   CB   C N N 331 
SER   OG   O N N 332 
SER   OXT  O N N 333 
SER   H    H N N 334 
SER   H2   H N N 335 
SER   HA   H N N 336 
SER   HB2  H N N 337 
SER   HB3  H N N 338 
SER   HG   H N N 339 
SER   HXT  H N N 340 
THR   N    N N N 341 
THR   CA   C N S 342 
THR   C    C N N 343 
THR   O    O N N 344 
THR   CB   C N R 345 
THR   OG1  O N N 346 
THR   CG2  C N N 347 
THR   OXT  O N N 348 
THR   H    H N N 349 
THR   H2   H N N 350 
THR   HA   H N N 351 
THR   HB   H N N 352 
THR   HG1  H N N 353 
THR   HG21 H N N 354 
THR   HG22 H N N 355 
THR   HG23 H N N 356 
THR   HXT  H N N 357 
TRP   N    N N N 358 
TRP   CA   C N S 359 
TRP   C    C N N 360 
TRP   O    O N N 361 
TRP   CB   C N N 362 
TRP   CG   C Y N 363 
TRP   CD1  C Y N 364 
TRP   CD2  C Y N 365 
TRP   NE1  N Y N 366 
TRP   CE2  C Y N 367 
TRP   CE3  C Y N 368 
TRP   CZ2  C Y N 369 
TRP   CZ3  C Y N 370 
TRP   CH2  C Y N 371 
TRP   OXT  O N N 372 
TRP   H    H N N 373 
TRP   H2   H N N 374 
TRP   HA   H N N 375 
TRP   HB2  H N N 376 
TRP   HB3  H N N 377 
TRP   HD1  H N N 378 
TRP   HE1  H N N 379 
TRP   HE3  H N N 380 
TRP   HZ2  H N N 381 
TRP   HZ3  H N N 382 
TRP   HH2  H N N 383 
TRP   HXT  H N N 384 
TYR   N    N N N 385 
TYR   CA   C N S 386 
TYR   C    C N N 387 
TYR   O    O N N 388 
TYR   CB   C N N 389 
TYR   CG   C Y N 390 
TYR   CD1  C Y N 391 
TYR   CD2  C Y N 392 
TYR   CE1  C Y N 393 
TYR   CE2  C Y N 394 
TYR   CZ   C Y N 395 
TYR   OH   O N N 396 
TYR   OXT  O N N 397 
TYR   H    H N N 398 
TYR   H2   H N N 399 
TYR   HA   H N N 400 
TYR   HB2  H N N 401 
TYR   HB3  H N N 402 
TYR   HD1  H N N 403 
TYR   HD2  H N N 404 
TYR   HE1  H N N 405 
TYR   HE2  H N N 406 
TYR   HH   H N N 407 
TYR   HXT  H N N 408 
VAL   N    N N N 409 
VAL   CA   C N S 410 
VAL   C    C N N 411 
VAL   O    O N N 412 
VAL   CB   C N N 413 
VAL   CG1  C N N 414 
VAL   CG2  C N N 415 
VAL   OXT  O N N 416 
VAL   H    H N N 417 
VAL   H2   H N N 418 
VAL   HA   H N N 419 
VAL   HB   H N N 420 
VAL   HG11 H N N 421 
VAL   HG12 H N N 422 
VAL   HG13 H N N 423 
VAL   HG21 H N N 424 
VAL   HG22 H N N 425 
VAL   HG23 H N N 426 
VAL   HXT  H N N 427 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1LZU O3  P1   doub N N 1   
A1LZU O5  P1   sing N N 2   
A1LZU P1  O2   sing N N 3   
A1LZU P1  O4   sing N N 4   
A1LZU O2  C13  sing N N 5   
A1LZU C11 C10  sing N N 6   
A1LZU C13 O1   sing N N 7   
A1LZU O1  C5   sing N N 8   
A1LZU C10 C12  sing N N 9   
A1LZU C10 C6   sing N N 10  
A1LZU C1  C2   sing N N 11  
A1LZU C5  C6   doub Y N 12  
A1LZU C5  C4   sing Y N 13  
A1LZU C6  C7   sing Y N 14  
A1LZU C2  C4   sing N N 15  
A1LZU C2  C3   sing N N 16  
A1LZU C4  C9   doub Y N 17  
A1LZU C7  C8   doub Y N 18  
A1LZU C9  C8   sing Y N 19  
A1LZU C1  H1   sing N N 20  
A1LZU C1  H2   sing N N 21  
A1LZU C1  H3   sing N N 22  
A1LZU C10 H4   sing N N 23  
A1LZU C11 H5   sing N N 24  
A1LZU C11 H6   sing N N 25  
A1LZU C11 H7   sing N N 26  
A1LZU C12 H8   sing N N 27  
A1LZU C12 H9   sing N N 28  
A1LZU C12 H10  sing N N 29  
A1LZU C13 H11  sing N N 30  
A1LZU C13 H12  sing N N 31  
A1LZU C2  H13  sing N N 32  
A1LZU C3  H14  sing N N 33  
A1LZU C3  H15  sing N N 34  
A1LZU C3  H16  sing N N 35  
A1LZU C7  H17  sing N N 36  
A1LZU C8  H18  sing N N 37  
A1LZU C9  H19  sing N N 38  
A1LZU O4  H20  sing N N 39  
A1LZU O5  H21  sing N N 40  
ALA   N   CA   sing N N 41  
ALA   N   H    sing N N 42  
ALA   N   H2   sing N N 43  
ALA   CA  C    sing N N 44  
ALA   CA  CB   sing N N 45  
ALA   CA  HA   sing N N 46  
ALA   C   O    doub N N 47  
ALA   C   OXT  sing N N 48  
ALA   CB  HB1  sing N N 49  
ALA   CB  HB2  sing N N 50  
ALA   CB  HB3  sing N N 51  
ALA   OXT HXT  sing N N 52  
ARG   N   CA   sing N N 53  
ARG   N   H    sing N N 54  
ARG   N   H2   sing N N 55  
ARG   CA  C    sing N N 56  
ARG   CA  CB   sing N N 57  
ARG   CA  HA   sing N N 58  
ARG   C   O    doub N N 59  
ARG   C   OXT  sing N N 60  
ARG   CB  CG   sing N N 61  
ARG   CB  HB2  sing N N 62  
ARG   CB  HB3  sing N N 63  
ARG   CG  CD   sing N N 64  
ARG   CG  HG2  sing N N 65  
ARG   CG  HG3  sing N N 66  
ARG   CD  NE   sing N N 67  
ARG   CD  HD2  sing N N 68  
ARG   CD  HD3  sing N N 69  
ARG   NE  CZ   sing N N 70  
ARG   NE  HE   sing N N 71  
ARG   CZ  NH1  sing N N 72  
ARG   CZ  NH2  doub N N 73  
ARG   NH1 HH11 sing N N 74  
ARG   NH1 HH12 sing N N 75  
ARG   NH2 HH21 sing N N 76  
ARG   NH2 HH22 sing N N 77  
ARG   OXT HXT  sing N N 78  
ASN   N   CA   sing N N 79  
ASN   N   H    sing N N 80  
ASN   N   H2   sing N N 81  
ASN   CA  C    sing N N 82  
ASN   CA  CB   sing N N 83  
ASN   CA  HA   sing N N 84  
ASN   C   O    doub N N 85  
ASN   C   OXT  sing N N 86  
ASN   CB  CG   sing N N 87  
ASN   CB  HB2  sing N N 88  
ASN   CB  HB3  sing N N 89  
ASN   CG  OD1  doub N N 90  
ASN   CG  ND2  sing N N 91  
ASN   ND2 HD21 sing N N 92  
ASN   ND2 HD22 sing N N 93  
ASN   OXT HXT  sing N N 94  
ASP   N   CA   sing N N 95  
ASP   N   H    sing N N 96  
ASP   N   H2   sing N N 97  
ASP   CA  C    sing N N 98  
ASP   CA  CB   sing N N 99  
ASP   CA  HA   sing N N 100 
ASP   C   O    doub N N 101 
ASP   C   OXT  sing N N 102 
ASP   CB  CG   sing N N 103 
ASP   CB  HB2  sing N N 104 
ASP   CB  HB3  sing N N 105 
ASP   CG  OD1  doub N N 106 
ASP   CG  OD2  sing N N 107 
ASP   OD2 HD2  sing N N 108 
ASP   OXT HXT  sing N N 109 
CYS   N   CA   sing N N 110 
CYS   N   H    sing N N 111 
CYS   N   H2   sing N N 112 
CYS   CA  C    sing N N 113 
CYS   CA  CB   sing N N 114 
CYS   CA  HA   sing N N 115 
CYS   C   O    doub N N 116 
CYS   C   OXT  sing N N 117 
CYS   CB  SG   sing N N 118 
CYS   CB  HB2  sing N N 119 
CYS   CB  HB3  sing N N 120 
CYS   SG  HG   sing N N 121 
CYS   OXT HXT  sing N N 122 
GLN   N   CA   sing N N 123 
GLN   N   H    sing N N 124 
GLN   N   H2   sing N N 125 
GLN   CA  C    sing N N 126 
GLN   CA  CB   sing N N 127 
GLN   CA  HA   sing N N 128 
GLN   C   O    doub N N 129 
GLN   C   OXT  sing N N 130 
GLN   CB  CG   sing N N 131 
GLN   CB  HB2  sing N N 132 
GLN   CB  HB3  sing N N 133 
GLN   CG  CD   sing N N 134 
GLN   CG  HG2  sing N N 135 
GLN   CG  HG3  sing N N 136 
GLN   CD  OE1  doub N N 137 
GLN   CD  NE2  sing N N 138 
GLN   NE2 HE21 sing N N 139 
GLN   NE2 HE22 sing N N 140 
GLN   OXT HXT  sing N N 141 
GLU   N   CA   sing N N 142 
GLU   N   H    sing N N 143 
GLU   N   H2   sing N N 144 
GLU   CA  C    sing N N 145 
GLU   CA  CB   sing N N 146 
GLU   CA  HA   sing N N 147 
GLU   C   O    doub N N 148 
GLU   C   OXT  sing N N 149 
GLU   CB  CG   sing N N 150 
GLU   CB  HB2  sing N N 151 
GLU   CB  HB3  sing N N 152 
GLU   CG  CD   sing N N 153 
GLU   CG  HG2  sing N N 154 
GLU   CG  HG3  sing N N 155 
GLU   CD  OE1  doub N N 156 
GLU   CD  OE2  sing N N 157 
GLU   OE2 HE2  sing N N 158 
GLU   OXT HXT  sing N N 159 
GLY   N   CA   sing N N 160 
GLY   N   H    sing N N 161 
GLY   N   H2   sing N N 162 
GLY   CA  C    sing N N 163 
GLY   CA  HA2  sing N N 164 
GLY   CA  HA3  sing N N 165 
GLY   C   O    doub N N 166 
GLY   C   OXT  sing N N 167 
GLY   OXT HXT  sing N N 168 
HIS   N   CA   sing N N 169 
HIS   N   H    sing N N 170 
HIS   N   H2   sing N N 171 
HIS   CA  C    sing N N 172 
HIS   CA  CB   sing N N 173 
HIS   CA  HA   sing N N 174 
HIS   C   O    doub N N 175 
HIS   C   OXT  sing N N 176 
HIS   CB  CG   sing N N 177 
HIS   CB  HB2  sing N N 178 
HIS   CB  HB3  sing N N 179 
HIS   CG  ND1  sing Y N 180 
HIS   CG  CD2  doub Y N 181 
HIS   ND1 CE1  doub Y N 182 
HIS   ND1 HD1  sing N N 183 
HIS   CD2 NE2  sing Y N 184 
HIS   CD2 HD2  sing N N 185 
HIS   CE1 NE2  sing Y N 186 
HIS   CE1 HE1  sing N N 187 
HIS   NE2 HE2  sing N N 188 
HIS   OXT HXT  sing N N 189 
ILE   N   CA   sing N N 190 
ILE   N   H    sing N N 191 
ILE   N   H2   sing N N 192 
ILE   CA  C    sing N N 193 
ILE   CA  CB   sing N N 194 
ILE   CA  HA   sing N N 195 
ILE   C   O    doub N N 196 
ILE   C   OXT  sing N N 197 
ILE   CB  CG1  sing N N 198 
ILE   CB  CG2  sing N N 199 
ILE   CB  HB   sing N N 200 
ILE   CG1 CD1  sing N N 201 
ILE   CG1 HG12 sing N N 202 
ILE   CG1 HG13 sing N N 203 
ILE   CG2 HG21 sing N N 204 
ILE   CG2 HG22 sing N N 205 
ILE   CG2 HG23 sing N N 206 
ILE   CD1 HD11 sing N N 207 
ILE   CD1 HD12 sing N N 208 
ILE   CD1 HD13 sing N N 209 
ILE   OXT HXT  sing N N 210 
LEU   N   CA   sing N N 211 
LEU   N   H    sing N N 212 
LEU   N   H2   sing N N 213 
LEU   CA  C    sing N N 214 
LEU   CA  CB   sing N N 215 
LEU   CA  HA   sing N N 216 
LEU   C   O    doub N N 217 
LEU   C   OXT  sing N N 218 
LEU   CB  CG   sing N N 219 
LEU   CB  HB2  sing N N 220 
LEU   CB  HB3  sing N N 221 
LEU   CG  CD1  sing N N 222 
LEU   CG  CD2  sing N N 223 
LEU   CG  HG   sing N N 224 
LEU   CD1 HD11 sing N N 225 
LEU   CD1 HD12 sing N N 226 
LEU   CD1 HD13 sing N N 227 
LEU   CD2 HD21 sing N N 228 
LEU   CD2 HD22 sing N N 229 
LEU   CD2 HD23 sing N N 230 
LEU   OXT HXT  sing N N 231 
LYS   N   CA   sing N N 232 
LYS   N   H    sing N N 233 
LYS   N   H2   sing N N 234 
LYS   CA  C    sing N N 235 
LYS   CA  CB   sing N N 236 
LYS   CA  HA   sing N N 237 
LYS   C   O    doub N N 238 
LYS   C   OXT  sing N N 239 
LYS   CB  CG   sing N N 240 
LYS   CB  HB2  sing N N 241 
LYS   CB  HB3  sing N N 242 
LYS   CG  CD   sing N N 243 
LYS   CG  HG2  sing N N 244 
LYS   CG  HG3  sing N N 245 
LYS   CD  CE   sing N N 246 
LYS   CD  HD2  sing N N 247 
LYS   CD  HD3  sing N N 248 
LYS   CE  NZ   sing N N 249 
LYS   CE  HE2  sing N N 250 
LYS   CE  HE3  sing N N 251 
LYS   NZ  HZ1  sing N N 252 
LYS   NZ  HZ2  sing N N 253 
LYS   NZ  HZ3  sing N N 254 
LYS   OXT HXT  sing N N 255 
MET   N   CA   sing N N 256 
MET   N   H    sing N N 257 
MET   N   H2   sing N N 258 
MET   CA  C    sing N N 259 
MET   CA  CB   sing N N 260 
MET   CA  HA   sing N N 261 
MET   C   O    doub N N 262 
MET   C   OXT  sing N N 263 
MET   CB  CG   sing N N 264 
MET   CB  HB2  sing N N 265 
MET   CB  HB3  sing N N 266 
MET   CG  SD   sing N N 267 
MET   CG  HG2  sing N N 268 
MET   CG  HG3  sing N N 269 
MET   SD  CE   sing N N 270 
MET   CE  HE1  sing N N 271 
MET   CE  HE2  sing N N 272 
MET   CE  HE3  sing N N 273 
MET   OXT HXT  sing N N 274 
PHE   N   CA   sing N N 275 
PHE   N   H    sing N N 276 
PHE   N   H2   sing N N 277 
PHE   CA  C    sing N N 278 
PHE   CA  CB   sing N N 279 
PHE   CA  HA   sing N N 280 
PHE   C   O    doub N N 281 
PHE   C   OXT  sing N N 282 
PHE   CB  CG   sing N N 283 
PHE   CB  HB2  sing N N 284 
PHE   CB  HB3  sing N N 285 
PHE   CG  CD1  doub Y N 286 
PHE   CG  CD2  sing Y N 287 
PHE   CD1 CE1  sing Y N 288 
PHE   CD1 HD1  sing N N 289 
PHE   CD2 CE2  doub Y N 290 
PHE   CD2 HD2  sing N N 291 
PHE   CE1 CZ   doub Y N 292 
PHE   CE1 HE1  sing N N 293 
PHE   CE2 CZ   sing Y N 294 
PHE   CE2 HE2  sing N N 295 
PHE   CZ  HZ   sing N N 296 
PHE   OXT HXT  sing N N 297 
PRO   N   CA   sing N N 298 
PRO   N   CD   sing N N 299 
PRO   N   H    sing N N 300 
PRO   CA  C    sing N N 301 
PRO   CA  CB   sing N N 302 
PRO   CA  HA   sing N N 303 
PRO   C   O    doub N N 304 
PRO   C   OXT  sing N N 305 
PRO   CB  CG   sing N N 306 
PRO   CB  HB2  sing N N 307 
PRO   CB  HB3  sing N N 308 
PRO   CG  CD   sing N N 309 
PRO   CG  HG2  sing N N 310 
PRO   CG  HG3  sing N N 311 
PRO   CD  HD2  sing N N 312 
PRO   CD  HD3  sing N N 313 
PRO   OXT HXT  sing N N 314 
SER   N   CA   sing N N 315 
SER   N   H    sing N N 316 
SER   N   H2   sing N N 317 
SER   CA  C    sing N N 318 
SER   CA  CB   sing N N 319 
SER   CA  HA   sing N N 320 
SER   C   O    doub N N 321 
SER   C   OXT  sing N N 322 
SER   CB  OG   sing N N 323 
SER   CB  HB2  sing N N 324 
SER   CB  HB3  sing N N 325 
SER   OG  HG   sing N N 326 
SER   OXT HXT  sing N N 327 
THR   N   CA   sing N N 328 
THR   N   H    sing N N 329 
THR   N   H2   sing N N 330 
THR   CA  C    sing N N 331 
THR   CA  CB   sing N N 332 
THR   CA  HA   sing N N 333 
THR   C   O    doub N N 334 
THR   C   OXT  sing N N 335 
THR   CB  OG1  sing N N 336 
THR   CB  CG2  sing N N 337 
THR   CB  HB   sing N N 338 
THR   OG1 HG1  sing N N 339 
THR   CG2 HG21 sing N N 340 
THR   CG2 HG22 sing N N 341 
THR   CG2 HG23 sing N N 342 
THR   OXT HXT  sing N N 343 
TRP   N   CA   sing N N 344 
TRP   N   H    sing N N 345 
TRP   N   H2   sing N N 346 
TRP   CA  C    sing N N 347 
TRP   CA  CB   sing N N 348 
TRP   CA  HA   sing N N 349 
TRP   C   O    doub N N 350 
TRP   C   OXT  sing N N 351 
TRP   CB  CG   sing N N 352 
TRP   CB  HB2  sing N N 353 
TRP   CB  HB3  sing N N 354 
TRP   CG  CD1  doub Y N 355 
TRP   CG  CD2  sing Y N 356 
TRP   CD1 NE1  sing Y N 357 
TRP   CD1 HD1  sing N N 358 
TRP   CD2 CE2  doub Y N 359 
TRP   CD2 CE3  sing Y N 360 
TRP   NE1 CE2  sing Y N 361 
TRP   NE1 HE1  sing N N 362 
TRP   CE2 CZ2  sing Y N 363 
TRP   CE3 CZ3  doub Y N 364 
TRP   CE3 HE3  sing N N 365 
TRP   CZ2 CH2  doub Y N 366 
TRP   CZ2 HZ2  sing N N 367 
TRP   CZ3 CH2  sing Y N 368 
TRP   CZ3 HZ3  sing N N 369 
TRP   CH2 HH2  sing N N 370 
TRP   OXT HXT  sing N N 371 
TYR   N   CA   sing N N 372 
TYR   N   H    sing N N 373 
TYR   N   H2   sing N N 374 
TYR   CA  C    sing N N 375 
TYR   CA  CB   sing N N 376 
TYR   CA  HA   sing N N 377 
TYR   C   O    doub N N 378 
TYR   C   OXT  sing N N 379 
TYR   CB  CG   sing N N 380 
TYR   CB  HB2  sing N N 381 
TYR   CB  HB3  sing N N 382 
TYR   CG  CD1  doub Y N 383 
TYR   CG  CD2  sing Y N 384 
TYR   CD1 CE1  sing Y N 385 
TYR   CD1 HD1  sing N N 386 
TYR   CD2 CE2  doub Y N 387 
TYR   CD2 HD2  sing N N 388 
TYR   CE1 CZ   doub Y N 389 
TYR   CE1 HE1  sing N N 390 
TYR   CE2 CZ   sing Y N 391 
TYR   CE2 HE2  sing N N 392 
TYR   CZ  OH   sing N N 393 
TYR   OH  HH   sing N N 394 
TYR   OXT HXT  sing N N 395 
VAL   N   CA   sing N N 396 
VAL   N   H    sing N N 397 
VAL   N   H2   sing N N 398 
VAL   CA  C    sing N N 399 
VAL   CA  CB   sing N N 400 
VAL   CA  HA   sing N N 401 
VAL   C   O    doub N N 402 
VAL   C   OXT  sing N N 403 
VAL   CB  CG1  sing N N 404 
VAL   CB  CG2  sing N N 405 
VAL   CB  HB   sing N N 406 
VAL   CG1 HG11 sing N N 407 
VAL   CG1 HG12 sing N N 408 
VAL   CG1 HG13 sing N N 409 
VAL   CG2 HG21 sing N N 410 
VAL   CG2 HG22 sing N N 411 
VAL   CG2 HG23 sing N N 412 
VAL   OXT HXT  sing N N 413 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                150 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         56.5 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)' 'United States' 
R01DA055656 1 
'National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)' 'United States' 
U24DK116195 2 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1LZU 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1LZU 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_atom_sites.entry_id                    8YRG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR   A 1 4   ? 119.648 104.708 104.317 1.00 81.26  ? 4   THR   B N   1 
ATOM   2    C CA  . THR   A 1 4   ? 120.905 105.152 104.907 1.00 81.26  ? 4   THR   B CA  1 
ATOM   3    C C   . THR   A 1 4   ? 121.539 106.262 104.076 1.00 81.26  ? 4   THR   B C   1 
ATOM   4    O O   . THR   A 1 4   ? 120.841 107.023 103.405 1.00 81.26  ? 4   THR   B O   1 
ATOM   5    C CB  . THR   A 1 4   ? 121.907 103.990 105.045 1.00 81.26  ? 4   THR   B CB  1 
ATOM   6    O OG1 . THR   A 1 4   ? 122.228 103.476 103.747 1.00 81.26  ? 4   THR   B OG1 1 
ATOM   7    C CG2 . THR   A 1 4   ? 121.315 102.876 105.895 1.00 81.26  ? 4   THR   B CG2 1 
ATOM   8    N N   . VAL   A 1 5   ? 122.865 106.349 104.123 1.00 75.06  ? 5   VAL   B N   1 
ATOM   9    C CA  . VAL   A 1 5   ? 123.623 107.355 103.391 1.00 75.06  ? 5   VAL   B CA  1 
ATOM   10   C C   . VAL   A 1 5   ? 124.640 106.654 102.503 1.00 75.06  ? 5   VAL   B C   1 
ATOM   11   O O   . VAL   A 1 5   ? 125.281 105.682 102.918 1.00 75.06  ? 5   VAL   B O   1 
ATOM   12   C CB  . VAL   A 1 5   ? 124.312 108.356 104.342 1.00 75.06  ? 5   VAL   B CB  1 
ATOM   13   C CG1 . VAL   A 1 5   ? 123.274 109.222 105.036 1.00 75.06  ? 5   VAL   B CG1 1 
ATOM   14   C CG2 . VAL   A 1 5   ? 125.160 107.625 105.369 1.00 75.06  ? 5   VAL   B CG2 1 
ATOM   15   N N   . SER   A 1 6   ? 124.773 107.140 101.273 1.00 67.92  ? 6   SER   B N   1 
ATOM   16   C CA  . SER   A 1 6   ? 125.695 106.547 100.324 1.00 67.92  ? 6   SER   B CA  1 
ATOM   17   C C   . SER   A 1 6   ? 127.136 106.791 100.759 1.00 67.92  ? 6   SER   B C   1 
ATOM   18   O O   . SER   A 1 6   ? 127.417 107.554 101.687 1.00 67.92  ? 6   SER   B O   1 
ATOM   19   C CB  . SER   A 1 6   ? 125.454 107.116 98.931  1.00 67.92  ? 6   SER   B CB  1 
ATOM   20   O OG  . SER   A 1 6   ? 125.408 108.530 98.967  1.00 67.92  ? 6   SER   B OG  1 
ATOM   21   N N   . ALA   A 1 7   ? 128.062 106.121 100.070 1.00 64.68  ? 7   ALA   B N   1 
ATOM   22   C CA  . ALA   A 1 7   ? 129.476 106.288 100.388 1.00 64.68  ? 7   ALA   B CA  1 
ATOM   23   C C   . ALA   A 1 7   ? 129.928 107.721 100.144 1.00 64.68  ? 7   ALA   B C   1 
ATOM   24   O O   . ALA   A 1 7   ? 130.684 108.294 100.944 1.00 64.68  ? 7   ALA   B O   1 
ATOM   25   C CB  . ALA   A 1 7   ? 130.312 105.311 99.566  1.00 64.68  ? 7   ALA   B CB  1 
ATOM   26   N N   . GLU   A 1 8   ? 129.463 108.321 99.050  1.00 62.97  ? 8   GLU   B N   1 
ATOM   27   C CA  . GLU   A 1 8   ? 129.842 109.692 98.747  1.00 62.97  ? 8   GLU   B CA  1 
ATOM   28   C C   . GLU   A 1 8   ? 129.309 110.666 99.787  1.00 62.97  ? 8   GLU   B C   1 
ATOM   29   O O   . GLU   A 1 8   ? 129.985 111.648 100.115 1.00 62.97  ? 8   GLU   B O   1 
ATOM   30   C CB  . GLU   A 1 8   ? 129.360 110.064 97.351  1.00 62.97  ? 8   GLU   B CB  1 
ATOM   31   C CG  . GLU   A 1 8   ? 130.015 109.247 96.261  1.00 62.97  ? 8   GLU   B CG  1 
ATOM   32   C CD  . GLU   A 1 8   ? 129.750 109.803 94.881  1.00 62.97  ? 8   GLU   B CD  1 
ATOM   33   O OE1 . GLU   A 1 8   ? 129.023 110.812 94.773  1.00 62.97  ? 8   GLU   B OE1 1 
ATOM   34   O OE2 . GLU   A 1 8   ? 130.270 109.230 93.903  1.00 62.97  ? 8   GLU   B OE2 1 
ATOM   35   N N   . ASP   A 1 9   ? 128.120 110.407 100.333 1.00 64.22  ? 9   ASP   B N   1 
ATOM   36   C CA  . ASP   A 1 9   ? 127.600 111.259 101.397 1.00 64.22  ? 9   ASP   B CA  1 
ATOM   37   C C   . ASP   A 1 9   ? 128.468 111.177 102.646 1.00 64.22  ? 9   ASP   B C   1 
ATOM   38   O O   . ASP   A 1 9   ? 128.723 112.194 103.303 1.00 64.22  ? 9   ASP   B O   1 
ATOM   39   C CB  . ASP   A 1 9   ? 126.159 110.878 101.718 1.00 64.22  ? 9   ASP   B CB  1 
ATOM   40   C CG  . ASP   A 1 9   ? 125.203 111.227 100.596 1.00 64.22  ? 9   ASP   B CG  1 
ATOM   41   O OD1 . ASP   A 1 9   ? 125.479 112.197 99.859  1.00 64.22  ? 9   ASP   B OD1 1 
ATOM   42   O OD2 . ASP   A 1 9   ? 124.175 110.533 100.451 1.00 64.22  ? 9   ASP   B OD2 1 
ATOM   43   N N   . LYS   A 1 10  ? 128.937 109.978 102.989 1.00 60.92  ? 10  LYS   B N   1 
ATOM   44   C CA  . LYS   A 1 10  ? 129.823 109.836 104.138 1.00 60.92  ? 10  LYS   B CA  1 
ATOM   45   C C   . LYS   A 1 10  ? 131.134 110.577 103.921 1.00 60.92  ? 10  LYS   B C   1 
ATOM   46   O O   . LYS   A 1 10  ? 131.644 111.242 104.834 1.00 60.92  ? 10  LYS   B O   1 
ATOM   47   C CB  . LYS   A 1 10  ? 130.088 108.360 104.412 1.00 60.92  ? 10  LYS   B CB  1 
ATOM   48   C CG  . LYS   A 1 10  ? 128.849 107.559 104.733 1.00 60.92  ? 10  LYS   B CG  1 
ATOM   49   C CD  . LYS   A 1 10  ? 129.185 106.363 105.600 1.00 60.92  ? 10  LYS   B CD  1 
ATOM   50   C CE  . LYS   A 1 10  ? 128.067 105.336 105.577 1.00 60.92  ? 10  LYS   B CE  1 
ATOM   51   N NZ  . LYS   A 1 10  ? 127.435 105.234 104.233 1.00 60.92  ? 10  LYS   B NZ  1 
ATOM   52   N N   . ALA   A 1 11  ? 131.705 110.467 102.722 1.00 54.93  ? 11  ALA   B N   1 
ATOM   53   C CA  . ALA   A 1 11  ? 132.950 111.177 102.453 1.00 54.93  ? 11  ALA   B CA  1 
ATOM   54   C C   . ALA   A 1 11  ? 132.742 112.685 102.490 1.00 54.93  ? 11  ALA   B C   1 
ATOM   55   O O   . ALA   A 1 11  ? 133.616 113.430 102.957 1.00 54.93  ? 11  ALA   B O   1 
ATOM   56   C CB  . ALA   A 1 11  ? 133.522 110.734 101.115 1.00 54.93  ? 11  ALA   B CB  1 
ATOM   57   N N   . ALA   A 1 12  ? 131.585 113.151 102.024 1.00 51.91  ? 12  ALA   B N   1 
ATOM   58   C CA  . ALA   A 1 12  ? 131.264 114.566 102.132 1.00 51.91  ? 12  ALA   B CA  1 
ATOM   59   C C   . ALA   A 1 12  ? 131.165 114.993 103.588 1.00 51.91  ? 12  ALA   B C   1 
ATOM   60   O O   . ALA   A 1 12  ? 131.624 116.080 103.961 1.00 51.91  ? 12  ALA   B O   1 
ATOM   61   C CB  . ALA   A 1 12  ? 129.968 114.864 101.390 1.00 51.91  ? 12  ALA   B CB  1 
ATOM   62   N N   . ALA   A 1 13  ? 130.582 114.142 104.429 1.00 53.97  ? 13  ALA   B N   1 
ATOM   63   C CA  . ALA   A 1 13  ? 130.513 114.440 105.853 1.00 53.97  ? 13  ALA   B CA  1 
ATOM   64   C C   . ALA   A 1 13  ? 131.904 114.567 106.458 1.00 53.97  ? 13  ALA   B C   1 
ATOM   65   O O   . ALA   A 1 13  ? 132.164 115.472 107.261 1.00 53.97  ? 13  ALA   B O   1 
ATOM   66   C CB  . ALA   A 1 13  ? 129.712 113.361 106.573 1.00 53.97  ? 13  ALA   B CB  1 
ATOM   67   N N   . GLU   A 1 14  ? 132.813 113.671 106.082 1.00 55.89  ? 14  GLU   B N   1 
ATOM   68   C CA  . GLU   A 1 14  ? 134.164 113.748 106.628 1.00 55.89  ? 14  GLU   B CA  1 
ATOM   69   C C   . GLU   A 1 14  ? 134.902 114.993 106.146 1.00 55.89  ? 14  GLU   B C   1 
ATOM   70   O O   . GLU   A 1 14  ? 135.676 115.596 106.904 1.00 55.89  ? 14  GLU   B O   1 
ATOM   71   C CB  . GLU   A 1 14  ? 134.944 112.484 106.296 1.00 55.89  ? 14  GLU   B CB  1 
ATOM   72   C CG  . GLU   A 1 14  ? 134.643 111.355 107.250 1.00 55.89  ? 14  GLU   B CG  1 
ATOM   73   C CD  . GLU   A 1 14  ? 135.718 110.291 107.253 1.00 55.89  ? 14  GLU   B CD  1 
ATOM   74   O OE1 . GLU   A 1 14  ? 136.325 110.047 106.189 1.00 55.89  ? 14  GLU   B OE1 1 
ATOM   75   O OE2 . GLU   A 1 14  ? 135.967 109.711 108.330 1.00 55.89  ? 14  GLU   B OE2 1 
ATOM   76   N N   . ARG   A 1 15  ? 134.682 115.398 104.896 1.00 51.52  ? 15  ARG   B N   1 
ATOM   77   C CA  . ARG   A 1 15  ? 135.259 116.656 104.430 1.00 51.52  ? 15  ARG   B CA  1 
ATOM   78   C C   . ARG   A 1 15  ? 134.719 117.834 105.231 1.00 51.52  ? 15  ARG   B C   1 
ATOM   79   O O   . ARG   A 1 15  ? 135.469 118.751 105.596 1.00 51.52  ? 15  ARG   B O   1 
ATOM   80   C CB  . ARG   A 1 15  ? 134.975 116.843 102.943 1.00 51.52  ? 15  ARG   B CB  1 
ATOM   81   C CG  . ARG   A 1 15  ? 135.456 118.153 102.373 1.00 51.52  ? 15  ARG   B CG  1 
ATOM   82   C CD  . ARG   A 1 15  ? 134.995 118.319 100.947 1.00 51.52  ? 15  ARG   B CD  1 
ATOM   83   N NE  . ARG   A 1 15  ? 135.520 119.526 100.325 1.00 51.52  ? 15  ARG   B NE  1 
ATOM   84   C CZ  . ARG   A 1 15  ? 136.778 119.680 99.943  1.00 51.52  ? 15  ARG   B CZ  1 
ATOM   85   N NH1 . ARG   A 1 15  ? 137.165 120.812 99.384  1.00 51.52  ? 15  ARG   B NH1 1 
ATOM   86   N NH2 . ARG   A 1 15  ? 137.649 118.699 100.108 1.00 51.52  ? 15  ARG   B NH2 1 
ATOM   87   N N   . SER   A 1 16  ? 133.419 117.821 105.519 1.00 52.17  ? 16  SER   B N   1 
ATOM   88   C CA  . SER   A 1 16  ? 132.836 118.873 106.339 1.00 52.17  ? 16  SER   B CA  1 
ATOM   89   C C   . SER   A 1 16  ? 133.462 118.900 107.723 1.00 52.17  ? 16  SER   B C   1 
ATOM   90   O O   . SER   A 1 16  ? 133.689 119.974 108.287 1.00 52.17  ? 16  SER   B O   1 
ATOM   91   C CB  . SER   A 1 16  ? 131.329 118.687 106.442 1.00 52.17  ? 16  SER   B CB  1 
ATOM   92   O OG  . SER   A 1 16  ? 130.781 119.574 107.396 1.00 52.17  ? 16  SER   B OG  1 
ATOM   93   N N   . LYS   A 1 17  ? 133.751 117.730 108.290 1.00 54.69  ? 17  LYS   B N   1 
ATOM   94   C CA  . LYS   A 1 17  ? 134.362 117.704 109.615 1.00 54.69  ? 17  LYS   B CA  1 
ATOM   95   C C   . LYS   A 1 17  ? 135.801 118.208 109.589 1.00 54.69  ? 17  LYS   B C   1 
ATOM   96   O O   . LYS   A 1 17  ? 136.241 118.878 110.531 1.00 54.69  ? 17  LYS   B O   1 
ATOM   97   C CB  . LYS   A 1 17  ? 134.288 116.305 110.217 1.00 54.69  ? 17  LYS   B CB  1 
ATOM   98   C CG  . LYS   A 1 17  ? 132.880 115.837 110.507 1.00 54.69  ? 17  LYS   B CG  1 
ATOM   99   C CD  . LYS   A 1 17  ? 132.881 114.490 111.197 1.00 54.69  ? 17  LYS   B CD  1 
ATOM   100  C CE  . LYS   A 1 17  ? 133.290 113.365 110.264 1.00 54.69  ? 17  LYS   B CE  1 
ATOM   101  N NZ  . LYS   A 1 17  ? 132.278 113.153 109.196 1.00 54.69  ? 17  LYS   B NZ  1 
ATOM   102  N N   . MET   A 1 18  ? 136.552 117.905 108.531 1.00 59.79  ? 18  MET   B N   1 
ATOM   103  C CA  . MET   A 1 18  ? 137.897 118.467 108.415 1.00 59.79  ? 18  MET   B CA  1 
ATOM   104  C C   . MET   A 1 18  ? 137.854 119.988 108.318 1.00 59.79  ? 18  MET   B C   1 
ATOM   105  O O   . MET   A 1 18  ? 138.647 120.691 108.967 1.00 59.79  ? 18  MET   B O   1 
ATOM   106  C CB  . MET   A 1 18  ? 138.618 117.875 107.209 1.00 59.79  ? 18  MET   B CB  1 
ATOM   107  C CG  . MET   A 1 18  ? 138.957 116.411 107.353 1.00 59.79  ? 18  MET   B CG  1 
ATOM   108  S SD  . MET   A 1 18  ? 140.222 115.883 106.184 1.00 59.79  ? 18  MET   B SD  1 
ATOM   109  C CE  . MET   A 1 18  ? 141.332 117.287 106.228 1.00 59.79  ? 18  MET   B CE  1 
ATOM   110  N N   . ILE   A 1 19  ? 136.915 120.516 107.531 1.00 56.84  ? 19  ILE   B N   1 
ATOM   111  C CA  . ILE   A 1 19  ? 136.755 121.964 107.441 1.00 56.84  ? 19  ILE   B CA  1 
ATOM   112  C C   . ILE   A 1 19  ? 136.363 122.545 108.795 1.00 56.84  ? 19  ILE   B C   1 
ATOM   113  O O   . ILE   A 1 19  ? 136.871 123.596 109.205 1.00 56.84  ? 19  ILE   B O   1 
ATOM   114  C CB  . ILE   A 1 19  ? 135.733 122.317 106.345 1.00 56.84  ? 19  ILE   B CB  1 
ATOM   115  C CG1 . ILE   A 1 19  ? 136.400 122.283 104.975 1.00 56.84  ? 19  ILE   B CG1 1 
ATOM   116  C CG2 . ILE   A 1 19  ? 135.134 123.682 106.580 1.00 56.84  ? 19  ILE   B CG2 1 
ATOM   117  C CD1 . ILE   A 1 19  ? 135.433 122.271 103.837 1.00 56.84  ? 19  ILE   B CD1 1 
ATOM   118  N N   . ASP   A 1 20  ? 135.447 121.881 109.503 1.00 59.41  ? 20  ASP   B N   1 
ATOM   119  C CA  . ASP   A 1 20  ? 135.041 122.324 110.834 1.00 59.41  ? 20  ASP   B CA  1 
ATOM   120  C C   . ASP   A 1 20  ? 136.232 122.413 111.775 1.00 59.41  ? 20  ASP   B C   1 
ATOM   121  O O   . ASP   A 1 20  ? 136.394 123.400 112.506 1.00 59.41  ? 20  ASP   B O   1 
ATOM   122  C CB  . ASP   A 1 20  ? 134.000 121.364 111.408 1.00 59.41  ? 20  ASP   B CB  1 
ATOM   123  C CG  . ASP   A 1 20  ? 132.609 121.646 110.906 1.00 59.41  ? 20  ASP   B CG  1 
ATOM   124  O OD1 . ASP   A 1 20  ? 132.366 122.790 110.484 1.00 59.41  ? 20  ASP   B OD1 1 
ATOM   125  O OD2 . ASP   A 1 20  ? 131.762 120.729 110.931 1.00 59.41  ? 20  ASP   B OD2 1 
ATOM   126  N N   . LYS   A 1 21  ? 137.068 121.379 111.782 1.00 63.04  ? 21  LYS   B N   1 
ATOM   127  C CA  . LYS   A 1 21  ? 138.243 121.395 112.640 1.00 63.04  ? 21  LYS   B CA  1 
ATOM   128  C C   . LYS   A 1 21  ? 139.129 122.587 112.312 1.00 63.04  ? 21  LYS   B C   1 
ATOM   129  O O   . LYS   A 1 21  ? 139.431 123.402 113.192 1.00 63.04  ? 21  LYS   B O   1 
ATOM   130  C CB  . LYS   A 1 21  ? 139.010 120.082 112.501 1.00 63.04  ? 21  LYS   B CB  1 
ATOM   131  C CG  . LYS   A 1 21  ? 140.492 120.184 112.774 1.00 63.04  ? 21  LYS   B CG  1 
ATOM   132  C CD  . LYS   A 1 21  ? 141.031 118.880 113.335 1.00 63.04  ? 21  LYS   B CD  1 
ATOM   133  C CE  . LYS   A 1 21  ? 140.971 117.769 112.303 1.00 63.04  ? 21  LYS   B CE  1 
ATOM   134  N NZ  . LYS   A 1 21  ? 142.067 117.881 111.302 1.00 63.04  ? 21  LYS   B NZ  1 
ATOM   135  N N   . ASN   A 1 22  ? 139.484 122.749 111.034 1.00 64.18  ? 22  ASN   B N   1 
ATOM   136  C CA  . ASN   A 1 22  ? 140.366 123.849 110.645 1.00 64.18  ? 22  ASN   B CA  1 
ATOM   137  C C   . ASN   A 1 22  ? 139.781 125.204 111.036 1.00 64.18  ? 22  ASN   B C   1 
ATOM   138  O O   . ASN   A 1 22  ? 140.510 126.100 111.485 1.00 64.18  ? 22  ASN   B O   1 
ATOM   139  C CB  . ASN   A 1 22  ? 140.637 123.796 109.146 1.00 64.18  ? 22  ASN   B CB  1 
ATOM   140  C CG  . ASN   A 1 22  ? 141.733 122.817 108.792 1.00 64.18  ? 22  ASN   B CG  1 
ATOM   141  O OD1 . ASN   A 1 22  ? 142.764 122.754 109.459 1.00 64.18  ? 22  ASN   B OD1 1 
ATOM   142  N ND2 . ASN   A 1 22  ? 141.518 122.045 107.733 1.00 64.18  ? 22  ASN   B ND2 1 
ATOM   143  N N   . LEU   A 1 23  ? 138.465 125.367 110.889 1.00 63.19  ? 23  LEU   B N   1 
ATOM   144  C CA  . LEU   A 1 23  ? 137.818 126.593 111.342 1.00 63.19  ? 23  LEU   B CA  1 
ATOM   145  C C   . LEU   A 1 23  ? 137.994 126.786 112.842 1.00 63.19  ? 23  LEU   B C   1 
ATOM   146  O O   . LEU   A 1 23  ? 138.223 127.909 113.307 1.00 63.19  ? 23  LEU   B O   1 
ATOM   147  C CB  . LEU   A 1 23  ? 136.333 126.569 110.989 1.00 63.19  ? 23  LEU   B CB  1 
ATOM   148  C CG  . LEU   A 1 23  ? 135.905 126.701 109.531 1.00 63.19  ? 23  LEU   B CG  1 
ATOM   149  C CD1 . LEU   A 1 23  ? 134.621 125.935 109.309 1.00 63.19  ? 23  LEU   B CD1 1 
ATOM   150  C CD2 . LEU   A 1 23  ? 135.708 128.147 109.177 1.00 63.19  ? 23  LEU   B CD2 1 
ATOM   151  N N   . ARG   A 1 24  ? 137.876 125.709 113.619 1.00 65.81  ? 24  ARG   B N   1 
ATOM   152  C CA  . ARG   A 1 24  ? 138.046 125.840 115.063 1.00 65.81  ? 24  ARG   B CA  1 
ATOM   153  C C   . ARG   A 1 24  ? 139.465 126.259 115.429 1.00 65.81  ? 24  ARG   B C   1 
ATOM   154  O O   . ARG   A 1 24  ? 139.652 127.087 116.329 1.00 65.81  ? 24  ARG   B O   1 
ATOM   155  C CB  . ARG   A 1 24  ? 137.674 124.543 115.776 1.00 65.81  ? 24  ARG   B CB  1 
ATOM   156  C CG  . ARG   A 1 24  ? 136.202 124.200 115.725 1.00 65.81  ? 24  ARG   B CG  1 
ATOM   157  C CD  . ARG   A 1 24  ? 135.905 122.938 116.518 1.00 65.81  ? 24  ARG   B CD  1 
ATOM   158  N NE  . ARG   A 1 24  ? 136.467 121.747 115.888 1.00 65.81  ? 24  ARG   B NE  1 
ATOM   159  C CZ  . ARG   A 1 24  ? 137.455 121.024 116.406 1.00 65.81  ? 24  ARG   B CZ  1 
ATOM   160  N NH1 . ARG   A 1 24  ? 137.904 119.954 115.764 1.00 65.81  ? 24  ARG   B NH1 1 
ATOM   161  N NH2 . ARG   A 1 24  ? 137.993 121.369 117.568 1.00 65.81  ? 24  ARG   B NH2 1 
ATOM   162  N N   . GLU   A 1 25  ? 140.486 125.689 114.775 1.00 66.12  ? 25  GLU   B N   1 
ATOM   163  C CA  . GLU   A 1 25  ? 141.835 126.156 115.107 1.00 66.12  ? 25  GLU   B CA  1 
ATOM   164  C C   . GLU   A 1 25  ? 142.042 127.603 114.681 1.00 66.12  ? 25  GLU   B C   1 
ATOM   165  O O   . GLU   A 1 25  ? 142.718 128.365 115.383 1.00 66.12  ? 25  GLU   B O   1 
ATOM   166  C CB  . GLU   A 1 25  ? 142.974 125.294 114.535 1.00 66.12  ? 25  GLU   B CB  1 
ATOM   167  C CG  . GLU   A 1 25  ? 143.199 123.914 115.168 1.00 66.12  ? 25  GLU   B CG  1 
ATOM   168  C CD  . GLU   A 1 25  ? 142.424 122.807 114.521 1.00 66.12  ? 25  GLU   B CD  1 
ATOM   169  O OE1 . GLU   A 1 25  ? 141.801 123.076 113.489 1.00 66.12  ? 25  GLU   B OE1 1 
ATOM   170  O OE2 . GLU   A 1 25  ? 142.439 121.673 115.043 1.00 66.12  ? 25  GLU   B OE2 1 
ATOM   171  N N   . ASP   A 1 26  ? 141.471 128.010 113.548 1.00 65.69  ? 26  ASP   B N   1 
ATOM   172  C CA  . ASP   A 1 26  ? 141.586 129.412 113.155 1.00 65.69  ? 26  ASP   B CA  1 
ATOM   173  C C   . ASP   A 1 26  ? 140.923 130.322 114.181 1.00 65.69  ? 26  ASP   B C   1 
ATOM   174  O O   . ASP   A 1 26  ? 141.426 131.413 114.475 1.00 65.69  ? 26  ASP   B O   1 
ATOM   175  C CB  . ASP   A 1 26  ? 140.978 129.622 111.771 1.00 65.69  ? 26  ASP   B CB  1 
ATOM   176  C CG  . ASP   A 1 26  ? 141.774 128.937 110.677 1.00 65.69  ? 26  ASP   B CG  1 
ATOM   177  O OD1 . ASP   A 1 26  ? 143.007 128.809 110.829 1.00 65.69  ? 26  ASP   B OD1 1 
ATOM   178  O OD2 . ASP   A 1 26  ? 141.167 128.519 109.669 1.00 65.69  ? 26  ASP   B OD2 1 
ATOM   179  N N   . GLY   A 1 27  ? 139.791 129.892 114.735 1.00 62.95  ? 27  GLY   B N   1 
ATOM   180  C CA  . GLY   A 1 27  ? 139.146 130.675 115.775 1.00 62.95  ? 27  GLY   B CA  1 
ATOM   181  C C   . GLY   A 1 27  ? 139.964 130.743 117.048 1.00 62.95  ? 27  GLY   B C   1 
ATOM   182  O O   . GLY   A 1 27  ? 140.103 131.811 117.651 1.00 62.95  ? 27  GLY   B O   1 
ATOM   183  N N   . GLU   A 1 28  ? 140.516 129.608 117.476 1.00 62.90  ? 28  GLU   B N   1 
ATOM   184  C CA  . GLU   A 1 28  ? 141.371 129.585 118.655 1.00 62.90  ? 28  GLU   B CA  1 
ATOM   185  C C   . GLU   A 1 28  ? 142.660 130.363 118.444 1.00 62.90  ? 28  GLU   B C   1 
ATOM   186  O O   . GLU   A 1 28  ? 143.333 130.698 119.423 1.00 62.90  ? 28  GLU   B O   1 
ATOM   187  C CB  . GLU   A 1 28  ? 141.693 128.143 119.046 1.00 62.90  ? 28  GLU   B CB  1 
ATOM   188  N N   . LYS   A 1 29  ? 143.027 130.638 117.195 1.00 62.95  ? 29  LYS   B N   1 
ATOM   189  C CA  . LYS   A 1 29  ? 144.181 131.489 116.936 1.00 62.95  ? 29  LYS   B CA  1 
ATOM   190  C C   . LYS   A 1 29  ? 143.802 132.962 116.955 1.00 62.95  ? 29  LYS   B C   1 
ATOM   191  O O   . LYS   A 1 29  ? 144.484 133.779 117.579 1.00 62.95  ? 29  LYS   B O   1 
ATOM   192  C CB  . LYS   A 1 29  ? 144.813 131.120 115.593 1.00 62.95  ? 29  LYS   B CB  1 
ATOM   193  C CG  . LYS   A 1 29  ? 146.085 131.864 115.280 1.00 62.95  ? 29  LYS   B CG  1 
ATOM   194  C CD  . LYS   A 1 29  ? 146.895 131.145 114.218 1.00 62.95  ? 29  LYS   B CD  1 
ATOM   195  C CE  . LYS   A 1 29  ? 146.967 129.649 114.483 1.00 62.95  ? 29  LYS   B CE  1 
ATOM   196  N NZ  . LYS   A 1 29  ? 147.947 129.322 115.556 1.00 62.95  ? 29  LYS   B NZ  1 
ATOM   197  N N   . ALA   A 1 30  ? 142.718 133.319 116.269 1.00 61.19  ? 30  ALA   B N   1 
ATOM   198  C CA  . ALA   A 1 30  ? 142.336 134.720 116.160 1.00 61.19  ? 30  ALA   B CA  1 
ATOM   199  C C   . ALA   A 1 30  ? 141.729 135.267 117.443 1.00 61.19  ? 30  ALA   B C   1 
ATOM   200  O O   . ALA   A 1 30  ? 141.680 136.489 117.615 1.00 61.19  ? 30  ALA   B O   1 
ATOM   201  C CB  . ALA   A 1 30  ? 141.353 134.906 115.005 1.00 61.19  ? 30  ALA   B CB  1 
ATOM   202  N N   . ARG   A 1 31  ? 141.261 134.402 118.340 1.00 60.80  ? 31  ARG   B N   1 
ATOM   203  C CA  . ARG   A 1 31  ? 140.665 134.887 119.576 1.00 60.80  ? 31  ARG   B CA  1 
ATOM   204  C C   . ARG   A 1 31  ? 141.675 135.619 120.446 1.00 60.80  ? 31  ARG   B C   1 
ATOM   205  O O   . ARG   A 1 31  ? 141.300 136.535 121.185 1.00 60.80  ? 31  ARG   B O   1 
ATOM   206  C CB  . ARG   A 1 31  ? 140.045 133.719 120.340 1.00 60.80  ? 31  ARG   B CB  1 
ATOM   207  C CG  . ARG   A 1 31  ? 139.418 134.092 121.662 1.00 60.80  ? 31  ARG   B CG  1 
ATOM   208  C CD  . ARG   A 1 31  ? 140.200 133.499 122.815 1.00 60.80  ? 31  ARG   B CD  1 
ATOM   209  N NE  . ARG   A 1 31  ? 140.249 132.044 122.752 1.00 60.80  ? 31  ARG   B NE  1 
ATOM   210  C CZ  . ARG   A 1 31  ? 139.287 131.246 123.200 1.00 60.80  ? 31  ARG   B CZ  1 
ATOM   211  N NH1 . ARG   A 1 31  ? 138.196 131.763 123.746 1.00 60.80  ? 31  ARG   B NH1 1 
ATOM   212  N NH2 . ARG   A 1 31  ? 139.415 129.932 123.104 1.00 60.80  ? 31  ARG   B NH2 1 
ATOM   213  N N   . ARG   A 1 32  ? 142.955 135.254 120.364 1.00 58.19  ? 32  ARG   B N   1 
ATOM   214  C CA  . ARG   A 1 32  ? 143.975 135.832 121.228 1.00 58.19  ? 32  ARG   B CA  1 
ATOM   215  C C   . ARG   A 1 32  ? 144.703 137.012 120.592 1.00 58.19  ? 32  ARG   B C   1 
ATOM   216  O O   . ARG   A 1 32  ? 145.885 137.230 120.880 1.00 58.19  ? 32  ARG   B O   1 
ATOM   217  C CB  . ARG   A 1 32  ? 144.974 134.761 121.665 1.00 58.19  ? 32  ARG   B CB  1 
ATOM   218  C CG  . ARG   A 1 32  ? 145.787 134.131 120.560 1.00 58.19  ? 32  ARG   B CG  1 
ATOM   219  C CD  . ARG   A 1 32  ? 146.484 132.884 121.067 1.00 58.19  ? 32  ARG   B CD  1 
ATOM   220  N NE  . ARG   A 1 32  ? 145.539 131.854 121.476 1.00 58.19  ? 32  ARG   B NE  1 
ATOM   221  C CZ  . ARG   A 1 32  ? 145.891 130.661 121.943 1.00 58.19  ? 32  ARG   B CZ  1 
ATOM   222  N NH1 . ARG   A 1 32  ? 144.962 129.782 122.292 1.00 58.19  ? 32  ARG   B NH1 1 
ATOM   223  N NH2 . ARG   A 1 32  ? 147.174 130.347 122.062 1.00 58.19  ? 32  ARG   B NH2 1 
ATOM   224  N N   . THR   A 1 33  ? 144.033 137.785 119.743 1.00 53.16  ? 33  THR   B N   1 
ATOM   225  C CA  . THR   A 1 33  ? 144.565 139.044 119.237 1.00 53.16  ? 33  THR   B CA  1 
ATOM   226  C C   . THR   A 1 33  ? 143.573 140.154 119.541 1.00 53.16  ? 33  THR   B C   1 
ATOM   227  O O   . THR   A 1 33  ? 142.433 140.118 119.066 1.00 53.16  ? 33  THR   B O   1 
ATOM   228  C CB  . THR   A 1 33  ? 144.831 138.984 117.732 1.00 53.16  ? 33  THR   B CB  1 
ATOM   229  O OG1 . THR   A 1 33  ? 143.591 139.071 117.024 1.00 53.16  ? 33  THR   B OG1 1 
ATOM   230  C CG2 . THR   A 1 33  ? 145.530 137.694 117.355 1.00 53.16  ? 33  THR   B CG2 1 
ATOM   231  N N   . LEU   A 1 34  ? 144.002 141.137 120.323 1.00 47.64  ? 34  LEU   B N   1 
ATOM   232  C CA  . LEU   A 1 34  ? 143.182 142.314 120.542 1.00 47.64  ? 34  LEU   B CA  1 
ATOM   233  C C   . LEU   A 1 34  ? 143.152 143.165 119.282 1.00 47.64  ? 34  LEU   B C   1 
ATOM   234  O O   . LEU   A 1 34  ? 144.077 143.147 118.471 1.00 47.64  ? 34  LEU   B O   1 
ATOM   235  C CB  . LEU   A 1 34  ? 143.698 143.118 121.728 1.00 47.64  ? 34  LEU   B CB  1 
ATOM   236  C CG  . LEU   A 1 34  ? 143.440 142.422 123.062 1.00 47.64  ? 34  LEU   B CG  1 
ATOM   237  C CD1 . LEU   A 1 34  ? 144.330 142.964 124.159 1.00 47.64  ? 34  LEU   B CD1 1 
ATOM   238  C CD2 . LEU   A 1 34  ? 141.978 142.552 123.448 1.00 47.64  ? 34  LEU   B CD2 1 
ATOM   239  N N   . ARG   A 1 35  ? 142.069 143.912 119.118 1.00 47.43  ? 35  ARG   B N   1 
ATOM   240  C CA  . ARG   A 1 35  ? 141.699 144.447 117.814 1.00 47.43  ? 35  ARG   B CA  1 
ATOM   241  C C   . ARG   A 1 35  ? 141.236 145.885 117.996 1.00 47.43  ? 35  ARG   B C   1 
ATOM   242  O O   . ARG   A 1 35  ? 140.189 146.131 118.600 1.00 47.43  ? 35  ARG   B O   1 
ATOM   243  C CB  . ARG   A 1 35  ? 140.621 143.562 117.193 1.00 47.43  ? 35  ARG   B CB  1 
ATOM   244  C CG  . ARG   A 1 35  ? 140.364 143.769 115.739 1.00 47.43  ? 35  ARG   B CG  1 
ATOM   245  C CD  . ARG   A 1 35  ? 139.558 142.614 115.186 1.00 47.43  ? 35  ARG   B CD  1 
ATOM   246  N NE  . ARG   A 1 35  ? 138.223 142.547 115.763 1.00 47.43  ? 35  ARG   B NE  1 
ATOM   247  C CZ  . ARG   A 1 35  ? 137.381 141.538 115.571 1.00 47.43  ? 35  ARG   B CZ  1 
ATOM   248  N NH1 . ARG   A 1 35  ? 137.738 140.509 114.815 1.00 47.43  ? 35  ARG   B NH1 1 
ATOM   249  N NH2 . ARG   A 1 35  ? 136.181 141.556 116.135 1.00 47.43  ? 35  ARG   B NH2 1 
ATOM   250  N N   . LEU   A 1 36  ? 142.016 146.831 117.479 1.00 39.73  ? 36  LEU   B N   1 
ATOM   251  C CA  . LEU   A 1 36  ? 141.911 148.240 117.825 1.00 39.73  ? 36  LEU   B CA  1 
ATOM   252  C C   . LEU   A 1 36  ? 141.679 149.079 116.579 1.00 39.73  ? 36  LEU   B C   1 
ATOM   253  O O   . LEU   A 1 36  ? 142.305 148.844 115.543 1.00 39.73  ? 36  LEU   B O   1 
ATOM   254  C CB  . LEU   A 1 36  ? 143.184 148.720 118.509 1.00 39.73  ? 36  LEU   B CB  1 
ATOM   255  C CG  . LEU   A 1 36  ? 143.440 148.382 119.964 1.00 39.73  ? 36  LEU   B CG  1 
ATOM   256  C CD1 . LEU   A 1 36  ? 143.766 146.914 120.154 1.00 39.73  ? 36  LEU   B CD1 1 
ATOM   257  C CD2 . LEU   A 1 36  ? 144.585 149.207 120.414 1.00 39.73  ? 36  LEU   B CD2 1 
ATOM   258  N N   . LEU   A 1 37  ? 140.800 150.071 116.680 1.00 37.94  ? 37  LEU   B N   1 
ATOM   259  C CA  . LEU   A 1 37  ? 140.494 150.960 115.568 1.00 37.94  ? 37  LEU   B CA  1 
ATOM   260  C C   . LEU   A 1 37  ? 141.046 152.345 115.849 1.00 37.94  ? 37  LEU   B C   1 
ATOM   261  O O   . LEU   A 1 37  ? 140.757 152.933 116.894 1.00 37.94  ? 37  LEU   B O   1 
ATOM   262  C CB  . LEU   A 1 37  ? 138.992 151.036 115.312 1.00 37.94  ? 37  LEU   B CB  1 
ATOM   263  C CG  . LEU   A 1 37  ? 138.514 152.160 114.398 1.00 37.94  ? 37  LEU   B CG  1 
ATOM   264  C CD1 . LEU   A 1 37  ? 139.029 151.981 112.994 1.00 37.94  ? 37  LEU   B CD1 1 
ATOM   265  C CD2 . LEU   A 1 37  ? 137.014 152.240 114.400 1.00 37.94  ? 37  LEU   B CD2 1 
ATOM   266  N N   . LEU   A 1 38  ? 141.827 152.862 114.915 1.00 40.46  ? 38  LEU   B N   1 
ATOM   267  C CA  . LEU   A 1 38  ? 142.511 154.136 115.059 1.00 40.46  ? 38  LEU   B CA  1 
ATOM   268  C C   . LEU   A 1 38  ? 141.817 155.181 114.202 1.00 40.46  ? 38  LEU   B C   1 
ATOM   269  O O   . LEU   A 1 38  ? 141.701 155.011 112.986 1.00 40.46  ? 38  LEU   B O   1 
ATOM   270  C CB  . LEU   A 1 38  ? 143.972 154.000 114.642 1.00 40.46  ? 38  LEU   B CB  1 
ATOM   271  C CG  . LEU   A 1 38  ? 144.806 155.247 114.400 1.00 40.46  ? 38  LEU   B CG  1 
ATOM   272  C CD1 . LEU   A 1 38  ? 145.108 155.947 115.700 1.00 40.46  ? 38  LEU   B CD1 1 
ATOM   273  C CD2 . LEU   A 1 38  ? 146.072 154.880 113.698 1.00 40.46  ? 38  LEU   B CD2 1 
ATOM   274  N N   . LEU   A 1 39  ? 141.355 156.253 114.830 1.00 42.03  ? 39  LEU   B N   1 
ATOM   275  C CA  . LEU   A 1 39  ? 140.744 157.367 114.124 1.00 42.03  ? 39  LEU   B CA  1 
ATOM   276  C C   . LEU   A 1 39  ? 141.509 158.638 114.450 1.00 42.03  ? 39  LEU   B C   1 
ATOM   277  O O   . LEU   A 1 39  ? 142.545 158.614 115.115 1.00 42.03  ? 39  LEU   B O   1 
ATOM   278  C CB  . LEU   A 1 39  ? 139.264 157.520 114.477 1.00 42.03  ? 39  LEU   B CB  1 
ATOM   279  C CG  . LEU   A 1 39  ? 138.331 156.432 113.982 1.00 42.03  ? 39  LEU   B CG  1 
ATOM   280  C CD1 . LEU   A 1 39  ? 137.139 156.332 114.886 1.00 42.03  ? 39  LEU   B CD1 1 
ATOM   281  C CD2 . LEU   A 1 39  ? 137.907 156.720 112.566 1.00 42.03  ? 39  LEU   B CD2 1 
ATOM   282  N N   . GLY   A 1 40  ? 140.982 159.759 113.985 1.00 51.46  ? 40  GLY   B N   1 
ATOM   283  C CA  . GLY   A 1 40  ? 141.686 161.019 114.058 1.00 51.46  ? 40  GLY   B CA  1 
ATOM   284  C C   . GLY   A 1 40  ? 141.834 161.567 112.660 1.00 51.46  ? 40  GLY   B C   1 
ATOM   285  O O   . GLY   A 1 40  ? 142.342 160.871 111.779 1.00 51.46  ? 40  GLY   B O   1 
ATOM   286  N N   . ALA   A 1 41  ? 141.400 162.804 112.432 1.00 61.28  ? 41  ALA   B N   1 
ATOM   287  C CA  . ALA   A 1 41  ? 141.147 163.240 111.063 1.00 61.28  ? 41  ALA   B CA  1 
ATOM   288  C C   . ALA   A 1 41  ? 142.442 163.413 110.281 1.00 61.28  ? 41  ALA   B C   1 
ATOM   289  O O   . ALA   A 1 41  ? 142.695 162.698 109.304 1.00 61.28  ? 41  ALA   B O   1 
ATOM   290  C CB  . ALA   A 1 41  ? 140.342 164.541 111.072 1.00 61.28  ? 41  ALA   B CB  1 
ATOM   291  N N   . ASP   A 1 42  ? 143.281 164.345 110.710 1.00 63.97  ? 42  ASP   B N   1 
ATOM   292  C CA  . ASP   A 1 42  ? 144.463 164.771 109.975 1.00 63.97  ? 42  ASP   B CA  1 
ATOM   293  C C   . ASP   A 1 42  ? 145.126 165.840 110.828 1.00 63.97  ? 42  ASP   B C   1 
ATOM   294  O O   . ASP   A 1 42  ? 144.589 166.247 111.863 1.00 63.97  ? 42  ASP   B O   1 
ATOM   295  C CB  . ASP   A 1 42  ? 144.132 165.313 108.584 1.00 63.97  ? 42  ASP   B CB  1 
ATOM   296  N N   . ASN   A 1 43  ? 146.295 166.296 110.373 1.00 64.92  ? 43  ASN   B N   1 
ATOM   297  C CA  . ASN   A 1 43  ? 147.161 167.200 111.122 1.00 64.92  ? 43  ASN   B CA  1 
ATOM   298  C C   . ASN   A 1 43  ? 147.177 166.826 112.597 1.00 64.92  ? 43  ASN   B C   1 
ATOM   299  O O   . ASN   A 1 43  ? 147.138 167.699 113.468 1.00 64.92  ? 43  ASN   B O   1 
ATOM   300  C CB  . ASN   A 1 43  ? 146.743 168.664 110.933 1.00 64.92  ? 43  ASN   B CB  1 
ATOM   301  C CG  . ASN   A 1 43  ? 145.323 168.943 111.388 1.00 64.92  ? 43  ASN   B CG  1 
ATOM   302  O OD1 . ASN   A 1 43  ? 144.374 168.815 110.614 1.00 64.92  ? 43  ASN   B OD1 1 
ATOM   303  N ND2 . ASN   A 1 43  ? 145.169 169.321 112.651 1.00 64.92  ? 43  ASN   B ND2 1 
ATOM   304  N N   . SER   A 1 44  ? 147.239 165.526 112.880 1.00 58.35  ? 44  SER   B N   1 
ATOM   305  C CA  . SER   A 1 44  ? 147.103 165.021 114.237 1.00 58.35  ? 44  SER   B CA  1 
ATOM   306  C C   . SER   A 1 44  ? 148.239 164.073 114.597 1.00 58.35  ? 44  SER   B C   1 
ATOM   307  O O   . SER   A 1 44  ? 148.642 163.997 115.762 1.00 58.35  ? 44  SER   B O   1 
ATOM   308  C CB  . SER   A 1 44  ? 145.758 164.324 114.392 1.00 58.35  ? 44  SER   B CB  1 
ATOM   309  O OG  . SER   A 1 44  ? 145.634 163.275 113.454 1.00 58.35  ? 44  SER   B OG  1 
ATOM   310  N N   . GLY   A 1 45  ? 148.762 163.348 113.616 1.00 55.31  ? 45  GLY   B N   1 
ATOM   311  C CA  . GLY   A 1 45  ? 149.921 162.515 113.853 1.00 55.31  ? 45  GLY   B CA  1 
ATOM   312  C C   . GLY   A 1 45  ? 149.617 161.042 114.018 1.00 55.31  ? 45  GLY   B C   1 
ATOM   313  O O   . GLY   A 1 45  ? 150.171 160.386 114.903 1.00 55.31  ? 45  GLY   B O   1 
ATOM   314  N N   . LYS   A 1 46  ? 148.742 160.509 113.169 1.00 53.11  ? 46  LYS   B N   1 
ATOM   315  C CA  . LYS   A 1 46  ? 148.381 159.100 113.263 1.00 53.11  ? 46  LYS   B CA  1 
ATOM   316  C C   . LYS   A 1 46  ? 149.583 158.196 113.024 1.00 53.11  ? 46  LYS   B C   1 
ATOM   317  O O   . LYS   A 1 46  ? 149.698 157.131 113.641 1.00 53.11  ? 46  LYS   B O   1 
ATOM   318  C CB  . LYS   A 1 46  ? 147.279 158.777 112.262 1.00 53.11  ? 46  LYS   B CB  1 
ATOM   319  C CG  . LYS   A 1 46  ? 145.922 159.280 112.640 1.00 53.11  ? 46  LYS   B CG  1 
ATOM   320  C CD  . LYS   A 1 46  ? 144.865 158.314 112.178 1.00 53.11  ? 46  LYS   B CD  1 
ATOM   321  C CE  . LYS   A 1 46  ? 144.320 158.698 110.820 1.00 53.11  ? 46  LYS   B CE  1 
ATOM   322  N NZ  . LYS   A 1 46  ? 143.507 157.605 110.212 1.00 53.11  ? 46  LYS   B NZ  1 
ATOM   323  N N   . SER   A 1 47  ? 150.476 158.591 112.119 1.00 59.66  ? 47  SER   B N   1 
ATOM   324  C CA  . SER   A 1 47  ? 151.580 157.719 111.732 1.00 59.66  ? 47  SER   B CA  1 
ATOM   325  C C   . SER   A 1 47  ? 152.505 157.422 112.905 1.00 59.66  ? 47  SER   B C   1 
ATOM   326  O O   . SER   A 1 47  ? 152.965 156.286 113.069 1.00 59.66  ? 47  SER   B O   1 
ATOM   327  C CB  . SER   A 1 47  ? 152.362 158.351 110.582 1.00 59.66  ? 47  SER   B CB  1 
ATOM   328  O OG  . SER   A 1 47  ? 152.816 159.648 110.926 1.00 59.66  ? 47  SER   B OG  1 
ATOM   329  N N   . THR   A 1 48  ? 152.788 158.424 113.733 1.00 62.29  ? 48  THR   B N   1 
ATOM   330  C CA  . THR   A 1 48  ? 153.764 158.304 114.814 1.00 62.29  ? 48  THR   B CA  1 
ATOM   331  C C   . THR   A 1 48  ? 153.111 158.061 116.167 1.00 62.29  ? 48  THR   B C   1 
ATOM   332  O O   . THR   A 1 48  ? 153.578 158.577 117.185 1.00 62.29  ? 48  THR   B O   1 
ATOM   333  C CB  . THR   A 1 48  ? 154.646 159.549 114.866 1.00 62.29  ? 48  THR   B CB  1 
ATOM   334  O OG1 . THR   A 1 48  ? 153.827 160.709 115.059 1.00 62.29  ? 48  THR   B OG1 1 
ATOM   335  C CG2 . THR   A 1 48  ? 155.431 159.700 113.571 1.00 62.29  ? 48  THR   B CG2 1 
ATOM   336  N N   . ILE   A 1 49  ? 152.029 157.288 116.218 1.00 57.52  ? 49  ILE   B N   1 
ATOM   337  C CA  . ILE   A 1 49  ? 151.428 156.934 117.501 1.00 57.52  ? 49  ILE   B CA  1 
ATOM   338  C C   . ILE   A 1 49  ? 152.186 155.786 118.153 1.00 57.52  ? 49  ILE   B C   1 
ATOM   339  O O   . ILE   A 1 49  ? 152.735 155.927 119.252 1.00 57.52  ? 49  ILE   B O   1 
ATOM   340  C CB  . ILE   A 1 49  ? 149.939 156.593 117.324 1.00 57.52  ? 49  ILE   B CB  1 
ATOM   341  C CG1 . ILE   A 1 49  ? 149.194 157.785 116.738 1.00 57.52  ? 49  ILE   B CG1 1 
ATOM   342  C CG2 . ILE   A 1 49  ? 149.329 156.177 118.642 1.00 57.52  ? 49  ILE   B CG2 1 
ATOM   343  C CD1 . ILE   A 1 49  ? 149.255 158.996 117.626 1.00 57.52  ? 49  ILE   B CD1 1 
ATOM   344  N N   . VAL   A 1 50  ? 152.229 154.634 117.488 1.00 58.17  ? 50  VAL   B N   1 
ATOM   345  C CA  . VAL   A 1 50  ? 152.963 153.467 117.967 1.00 58.17  ? 50  VAL   B CA  1 
ATOM   346  C C   . VAL   A 1 50  ? 154.109 153.213 117.003 1.00 58.17  ? 50  VAL   B C   1 
ATOM   347  O O   . VAL   A 1 50  ? 153.883 152.929 115.821 1.00 58.17  ? 50  VAL   B O   1 
ATOM   348  C CB  . VAL   A 1 50  ? 152.059 152.234 118.084 1.00 58.17  ? 50  VAL   B CB  1 
ATOM   349  C CG1 . VAL   A 1 50  ? 152.900 150.980 118.262 1.00 58.17  ? 50  VAL   B CG1 1 
ATOM   350  C CG2 . VAL   A 1 50  ? 151.098 152.398 119.244 1.00 58.17  ? 50  VAL   B CG2 1 
ATOM   351  N N   . LYS   A 1 51  ? 155.333 153.315 117.505 1.00 57.46  ? 51  LYS   B N   1 
ATOM   352  C CA  . LYS   A 1 51  ? 156.524 153.186 116.679 1.00 57.46  ? 51  LYS   B CA  1 
ATOM   353  C C   . LYS   A 1 51  ? 156.599 151.822 116.008 1.00 57.46  ? 51  LYS   B C   1 
ATOM   354  O O   . LYS   A 1 51  ? 157.547 151.068 116.211 1.00 57.46  ? 51  LYS   B O   1 
ATOM   355  C CB  . LYS   A 1 51  ? 157.775 153.424 117.521 1.00 57.46  ? 51  LYS   B CB  1 
ATOM   356  N N   . GLY   A 1 68  ? 142.777 151.383 100.989 1.00 56.94  ? 68  GLY   B N   1 
ATOM   357  C CA  . GLY   A 1 68  ? 142.069 150.477 101.874 1.00 56.94  ? 68  GLY   B CA  1 
ATOM   358  C C   . GLY   A 1 68  ? 142.548 150.569 103.304 1.00 56.94  ? 68  GLY   B C   1 
ATOM   359  O O   . GLY   A 1 68  ? 143.287 151.487 103.651 1.00 56.94  ? 68  GLY   B O   1 
ATOM   360  N N   . ILE   A 1 69  ? 142.122 149.625 104.141 1.00 52.08  ? 69  ILE   B N   1 
ATOM   361  C CA  . ILE   A 1 69  ? 142.563 149.608 105.526 1.00 52.08  ? 69  ILE   B CA  1 
ATOM   362  C C   . ILE   A 1 69  ? 144.058 149.342 105.584 1.00 52.08  ? 69  ILE   B C   1 
ATOM   363  O O   . ILE   A 1 69  ? 144.567 148.416 104.939 1.00 52.08  ? 69  ILE   B O   1 
ATOM   364  C CB  . ILE   A 1 69  ? 141.791 148.557 106.333 1.00 52.08  ? 69  ILE   B CB  1 
ATOM   365  C CG1 . ILE   A 1 69  ? 140.310 148.893 106.384 1.00 52.08  ? 69  ILE   B CG1 1 
ATOM   366  C CG2 . ILE   A 1 69  ? 142.355 148.437 107.740 1.00 52.08  ? 69  ILE   B CG2 1 
ATOM   367  C CD1 . ILE   A 1 69  ? 139.473 147.773 106.939 1.00 52.08  ? 69  ILE   B CD1 1 
ATOM   368  N N   . PHE   A 1 70  ? 144.770 150.156 106.351 1.00 49.19  ? 70  PHE   B N   1 
ATOM   369  C CA  . PHE   A 1 70  ? 146.140 149.862 106.736 1.00 49.19  ? 70  PHE   B CA  1 
ATOM   370  C C   . PHE   A 1 70  ? 146.114 149.222 108.116 1.00 49.19  ? 70  PHE   B C   1 
ATOM   371  O O   . PHE   A 1 70  ? 145.418 149.704 109.012 1.00 49.19  ? 70  PHE   B O   1 
ATOM   372  C CB  . PHE   A 1 70  ? 146.995 151.129 106.730 1.00 49.19  ? 70  PHE   B CB  1 
ATOM   373  N N   . GLU   A 1 71  ? 146.845 148.125 108.280 1.00 47.86  ? 71  GLU   B N   1 
ATOM   374  C CA  . GLU   A 1 71  ? 146.808 147.339 109.509 1.00 47.86  ? 71  GLU   B CA  1 
ATOM   375  C C   . GLU   A 1 71  ? 148.215 147.207 110.066 1.00 47.86  ? 71  GLU   B C   1 
ATOM   376  O O   . GLU   A 1 71  ? 149.066 146.542 109.466 1.00 47.86  ? 71  GLU   B O   1 
ATOM   377  C CB  . GLU   A 1 71  ? 146.193 145.966 109.259 1.00 47.86  ? 71  GLU   B CB  1 
ATOM   378  N N   . THR   A 1 72  ? 148.457 147.830 111.212 1.00 49.45  ? 72  THR   B N   1 
ATOM   379  C CA  . THR   A 1 72  ? 149.735 147.764 111.901 1.00 49.45  ? 72  THR   B CA  1 
ATOM   380  C C   . THR   A 1 72  ? 149.600 146.844 113.102 1.00 49.45  ? 72  THR   B C   1 
ATOM   381  O O   . THR   A 1 72  ? 148.680 147.003 113.910 1.00 49.45  ? 72  THR   B O   1 
ATOM   382  C CB  . THR   A 1 72  ? 150.193 149.149 112.355 1.00 49.45  ? 72  THR   B CB  1 
ATOM   383  O OG1 . THR   A 1 72  ? 150.352 150.000 111.214 1.00 49.45  ? 72  THR   B OG1 1 
ATOM   384  C CG2 . THR   A 1 72  ? 151.513 149.058 113.103 1.00 49.45  ? 72  THR   B CG2 1 
ATOM   385  N N   . LYS   A 1 73  ? 150.513 145.891 113.219 1.00 46.24  ? 73  LYS   B N   1 
ATOM   386  C CA  . LYS   A 1 73  ? 150.481 144.895 114.274 1.00 46.24  ? 73  LYS   B CA  1 
ATOM   387  C C   . LYS   A 1 73  ? 151.681 145.086 115.185 1.00 46.24  ? 73  LYS   B C   1 
ATOM   388  O O   . LYS   A 1 73  ? 152.812 145.200 114.708 1.00 46.24  ? 73  LYS   B O   1 
ATOM   389  C CB  . LYS   A 1 73  ? 150.480 143.486 113.686 1.00 46.24  ? 73  LYS   B CB  1 
ATOM   390  N N   . PHE   A 1 74  ? 151.435 145.128 116.491 1.00 46.65  ? 74  PHE   B N   1 
ATOM   391  C CA  . PHE   A 1 74  ? 152.512 145.200 117.464 1.00 46.65  ? 74  PHE   B CA  1 
ATOM   392  C C   . PHE   A 1 74  ? 152.183 144.311 118.651 1.00 46.65  ? 74  PHE   B C   1 
ATOM   393  O O   . PHE   A 1 74  ? 151.019 144.009 118.924 1.00 46.65  ? 74  PHE   B O   1 
ATOM   394  C CB  . PHE   A 1 74  ? 152.788 146.636 117.920 1.00 46.65  ? 74  PHE   B CB  1 
ATOM   395  C CG  . PHE   A 1 74  ? 151.608 147.342 118.517 1.00 46.65  ? 74  PHE   B CG  1 
ATOM   396  C CD1 . PHE   A 1 74  ? 150.606 147.840 117.723 1.00 46.65  ? 74  PHE   B CD1 1 
ATOM   397  C CD2 . PHE   A 1 74  ? 151.540 147.562 119.872 1.00 46.65  ? 74  PHE   B CD2 1 
ATOM   398  C CE1 . PHE   A 1 74  ? 149.545 148.508 118.274 1.00 46.65  ? 74  PHE   B CE1 1 
ATOM   399  C CE2 . PHE   A 1 74  ? 150.480 148.228 120.421 1.00 46.65  ? 74  PHE   B CE2 1 
ATOM   400  C CZ  . PHE   A 1 74  ? 149.484 148.700 119.623 1.00 46.65  ? 74  PHE   B CZ  1 
ATOM   401  N N   . GLN   A 1 75  ? 153.228 143.877 119.346 1.00 50.64  ? 75  GLN   B N   1 
ATOM   402  C CA  . GLN   A 1 75  ? 153.096 142.955 120.466 1.00 50.64  ? 75  GLN   B CA  1 
ATOM   403  C C   . GLN   A 1 75  ? 153.800 143.549 121.670 1.00 50.64  ? 75  GLN   B C   1 
ATOM   404  O O   . GLN   A 1 75  ? 154.982 143.898 121.589 1.00 50.64  ? 75  GLN   B O   1 
ATOM   405  C CB  . GLN   A 1 75  ? 153.683 141.583 120.129 1.00 50.64  ? 75  GLN   B CB  1 
ATOM   406  N N   . VAL   A 1 76  ? 153.075 143.679 122.776 1.00 51.01  ? 76  VAL   B N   1 
ATOM   407  C CA  . VAL   A 1 76  ? 153.653 144.058 124.057 1.00 51.01  ? 76  VAL   B CA  1 
ATOM   408  C C   . VAL   A 1 76  ? 153.120 143.112 125.120 1.00 51.01  ? 76  VAL   B C   1 
ATOM   409  O O   . VAL   A 1 76  ? 151.929 142.786 125.134 1.00 51.01  ? 76  VAL   B O   1 
ATOM   410  C CB  . VAL   A 1 76  ? 153.360 145.526 124.422 1.00 51.01  ? 76  VAL   B CB  1 
ATOM   411  C CG1 . VAL   A 1 76  ? 153.974 146.458 123.395 1.00 51.01  ? 76  VAL   B CG1 1 
ATOM   412  C CG2 . VAL   A 1 76  ? 151.881 145.769 124.531 1.00 51.01  ? 76  VAL   B CG2 1 
ATOM   413  N N   . ASP   A 1 77  ? 154.015 142.647 125.990 1.00 52.39  ? 77  ASP   B N   1 
ATOM   414  C CA  . ASP   A 1 77  ? 153.667 141.715 127.061 1.00 52.39  ? 77  ASP   B CA  1 
ATOM   415  C C   . ASP   A 1 77  ? 152.986 140.463 126.513 1.00 52.39  ? 77  ASP   B C   1 
ATOM   416  O O   . ASP   A 1 77  ? 152.006 139.970 127.074 1.00 52.39  ? 77  ASP   B O   1 
ATOM   417  C CB  . ASP   A 1 77  ? 152.794 142.392 128.119 1.00 52.39  ? 77  ASP   B CB  1 
ATOM   418  N N   . LYS   A 1 78  ? 153.497 139.963 125.390 1.00 52.49  ? 78  LYS   B N   1 
ATOM   419  C CA  . LYS   A 1 78  ? 153.120 138.679 124.812 1.00 52.49  ? 78  LYS   B CA  1 
ATOM   420  C C   . LYS   A 1 78  ? 151.681 138.634 124.308 1.00 52.49  ? 78  LYS   B C   1 
ATOM   421  O O   . LYS   A 1 78  ? 151.144 137.547 124.081 1.00 52.49  ? 78  LYS   B O   1 
ATOM   422  C CB  . LYS   A 1 78  ? 153.354 137.536 125.805 1.00 52.49  ? 78  LYS   B CB  1 
ATOM   423  N N   . VAL   A 1 79  ? 151.034 139.782 124.117 1.00 50.46  ? 79  VAL   B N   1 
ATOM   424  C CA  . VAL   A 1 79  ? 149.705 139.846 123.524 1.00 50.46  ? 79  VAL   B CA  1 
ATOM   425  C C   . VAL   A 1 79  ? 149.786 140.706 122.275 1.00 50.46  ? 79  VAL   B C   1 
ATOM   426  O O   . VAL   A 1 79  ? 150.480 141.728 122.256 1.00 50.46  ? 79  VAL   B O   1 
ATOM   427  C CB  . VAL   A 1 79  ? 148.651 140.385 124.510 1.00 50.46  ? 79  VAL   B CB  1 
ATOM   428  C CG1 . VAL   A 1 79  ? 148.929 141.822 124.886 1.00 50.46  ? 79  VAL   B CG1 1 
ATOM   429  C CG2 . VAL   A 1 79  ? 147.265 140.245 123.924 1.00 50.46  ? 79  VAL   B CG2 1 
ATOM   430  N N   . ASN   A 1 80  ? 149.109 140.272 121.220 1.00 51.16  ? 80  ASN   B N   1 
ATOM   431  C CA  . ASN   A 1 80  ? 149.208 140.942 119.936 1.00 51.16  ? 80  ASN   B CA  1 
ATOM   432  C C   . ASN   A 1 80  ? 148.073 141.938 119.760 1.00 51.16  ? 80  ASN   B C   1 
ATOM   433  O O   . ASN   A 1 80  ? 146.974 141.759 120.290 1.00 51.16  ? 80  ASN   B O   1 
ATOM   434  C CB  . ASN   A 1 80  ? 149.193 139.926 118.798 1.00 51.16  ? 80  ASN   B CB  1 
ATOM   435  C CG  . ASN   A 1 80  ? 150.480 139.149 118.701 1.00 51.16  ? 80  ASN   B CG  1 
ATOM   436  O OD1 . ASN   A 1 80  ? 150.525 137.962 119.012 1.00 51.16  ? 80  ASN   B OD1 1 
ATOM   437  N ND2 . ASN   A 1 80  ? 151.539 139.813 118.258 1.00 51.16  ? 80  ASN   B ND2 1 
ATOM   438  N N   . PHE   A 1 81  ? 148.353 142.998 119.012 1.00 46.08  ? 81  PHE   B N   1 
ATOM   439  C CA  . PHE   A 1 81  ? 147.387 144.045 118.727 1.00 46.08  ? 81  PHE   B CA  1 
ATOM   440  C C   . PHE   A 1 81  ? 147.346 144.292 117.231 1.00 46.08  ? 81  PHE   B C   1 
ATOM   441  O O   . PHE   A 1 81  ? 148.389 144.320 116.577 1.00 46.08  ? 81  PHE   B O   1 
ATOM   442  C CB  . PHE   A 1 81  ? 147.752 145.344 119.421 1.00 46.08  ? 81  PHE   B CB  1 
ATOM   443  C CG  . PHE   A 1 81  ? 147.772 145.262 120.907 1.00 46.08  ? 81  PHE   B CG  1 
ATOM   444  C CD1 . PHE   A 1 81  ? 146.609 145.247 121.623 1.00 46.08  ? 81  PHE   B CD1 1 
ATOM   445  C CD2 . PHE   A 1 81  ? 148.958 145.251 121.585 1.00 46.08  ? 81  PHE   B CD2 1 
ATOM   446  C CE1 . PHE   A 1 81  ? 146.629 145.200 122.978 1.00 46.08  ? 81  PHE   B CE1 1 
ATOM   447  C CE2 . PHE   A 1 81  ? 148.978 145.200 122.936 1.00 46.08  ? 81  PHE   B CE2 1 
ATOM   448  C CZ  . PHE   A 1 81  ? 147.813 145.175 123.636 1.00 46.08  ? 81  PHE   B CZ  1 
ATOM   449  N N   . HIS   A 1 82  ? 146.150 144.473 116.693 1.00 47.60  ? 82  HIS   B N   1 
ATOM   450  C CA  . HIS   A 1 82  ? 145.967 144.915 115.319 1.00 47.60  ? 82  HIS   B CA  1 
ATOM   451  C C   . HIS   A 1 82  ? 145.311 146.284 115.351 1.00 47.60  ? 82  HIS   B C   1 
ATOM   452  O O   . HIS   A 1 82  ? 144.243 146.448 115.951 1.00 47.60  ? 82  HIS   B O   1 
ATOM   453  C CB  . HIS   A 1 82  ? 145.119 143.922 114.534 1.00 47.60  ? 82  HIS   B CB  1 
ATOM   454  C CG  . HIS   A 1 82  ? 145.915 142.858 113.851 1.00 47.60  ? 82  HIS   B CG  1 
ATOM   455  N ND1 . HIS   A 1 82  ? 146.114 141.611 114.400 1.00 47.60  ? 82  HIS   B ND1 1 
ATOM   456  C CD2 . HIS   A 1 82  ? 146.554 142.849 112.658 1.00 47.60  ? 82  HIS   B CD2 1 
ATOM   457  C CE1 . HIS   A 1 82  ? 146.848 140.883 113.579 1.00 47.60  ? 82  HIS   B CE1 1 
ATOM   458  N NE2 . HIS   A 1 82  ? 147.128 141.611 112.514 1.00 47.60  ? 82  HIS   B NE2 1 
ATOM   459  N N   . MET   A 1 83  ? 145.944 147.260 114.716 1.00 47.68  ? 83  MET   B N   1 
ATOM   460  C CA  . MET   A 1 83  ? 145.560 148.660 114.848 1.00 47.68  ? 83  MET   B CA  1 
ATOM   461  C C   . MET   A 1 83  ? 145.226 149.203 113.464 1.00 47.68  ? 83  MET   B C   1 
ATOM   462  O O   . MET   A 1 83  ? 146.101 149.697 112.753 1.00 47.68  ? 83  MET   B O   1 
ATOM   463  C CB  . MET   A 1 83  ? 146.680 149.432 115.514 1.00 47.68  ? 83  MET   B CB  1 
ATOM   464  C CG  . MET   A 1 83  ? 146.399 150.882 115.796 1.00 47.68  ? 83  MET   B CG  1 
ATOM   465  S SD  . MET   A 1 83  ? 147.791 151.609 116.666 1.00 47.68  ? 83  MET   B SD  1 
ATOM   466  C CE  . MET   A 1 83  ? 147.279 153.316 116.790 1.00 47.68  ? 83  MET   B CE  1 
ATOM   467  N N   . PHE   A 1 84  ? 143.957 149.110 113.084 1.00 45.07  ? 84  PHE   B N   1 
ATOM   468  C CA  . PHE   A 1 84  ? 143.523 149.520 111.760 1.00 45.07  ? 84  PHE   B CA  1 
ATOM   469  C C   . PHE   A 1 84  ? 143.246 151.011 111.700 1.00 45.07  ? 84  PHE   B C   1 
ATOM   470  O O   . PHE   A 1 84  ? 142.863 151.636 112.691 1.00 45.07  ? 84  PHE   B O   1 
ATOM   471  C CB  . PHE   A 1 84  ? 142.272 148.757 111.352 1.00 45.07  ? 84  PHE   B CB  1 
ATOM   472  C CG  . PHE   A 1 84  ? 142.287 147.336 111.760 1.00 45.07  ? 84  PHE   B CG  1 
ATOM   473  C CD1 . PHE   A 1 84  ? 142.971 146.398 111.015 1.00 45.07  ? 84  PHE   B CD1 1 
ATOM   474  C CD2 . PHE   A 1 84  ? 141.631 146.929 112.889 1.00 45.07  ? 84  PHE   B CD2 1 
ATOM   475  C CE1 . PHE   A 1 84  ? 142.994 145.076 111.396 1.00 45.07  ? 84  PHE   B CE1 1 
ATOM   476  C CE2 . PHE   A 1 84  ? 141.655 145.612 113.273 1.00 45.07  ? 84  PHE   B CE2 1 
ATOM   477  C CZ  . PHE   A 1 84  ? 142.339 144.684 112.530 1.00 45.07  ? 84  PHE   B CZ  1 
ATOM   478  N N   . ASP   A 1 85  ? 143.440 151.579 110.515 1.00 50.38  ? 85  ASP   B N   1 
ATOM   479  C CA  . ASP   A 1 85  ? 143.058 152.960 110.251 1.00 50.38  ? 85  ASP   B CA  1 
ATOM   480  C C   . ASP   A 1 85  ? 142.595 153.060 108.808 1.00 50.38  ? 85  ASP   B C   1 
ATOM   481  O O   . ASP   A 1 85  ? 143.355 152.746 107.888 1.00 50.38  ? 85  ASP   B O   1 
ATOM   482  C CB  . ASP   A 1 85  ? 144.209 153.926 110.528 1.00 50.38  ? 85  ASP   B CB  1 
ATOM   483  C CG  . ASP   A 1 85  ? 145.520 153.463 109.939 1.00 50.38  ? 85  ASP   B CG  1 
ATOM   484  O OD1 . ASP   A 1 85  ? 145.590 152.315 109.465 1.00 50.38  ? 85  ASP   B OD1 1 
ATOM   485  O OD2 . ASP   A 1 85  ? 146.487 154.253 109.950 1.00 50.38  ? 85  ASP   B OD2 1 
ATOM   486  N N   . VAL   A 1 86  ? 141.356 153.487 108.613 1.00 54.49  ? 86  VAL   B N   1 
ATOM   487  C CA  . VAL   A 1 86  ? 140.740 153.503 107.294 1.00 54.49  ? 86  VAL   B CA  1 
ATOM   488  C C   . VAL   A 1 86  ? 140.967 154.868 106.663 1.00 54.49  ? 86  VAL   B C   1 
ATOM   489  O O   . VAL   A 1 86  ? 140.559 155.895 107.217 1.00 54.49  ? 86  VAL   B O   1 
ATOM   490  C CB  . VAL   A 1 86  ? 139.243 153.179 107.380 1.00 54.49  ? 86  VAL   B CB  1 
ATOM   491  C CG1 . VAL   A 1 86  ? 138.611 153.223 105.998 1.00 54.49  ? 86  VAL   B CG1 1 
ATOM   492  C CG2 . VAL   A 1 86  ? 139.038 151.832 108.030 1.00 54.49  ? 86  VAL   B CG2 1 
ATOM   493  N N   . GLY   A 1 87  ? 141.613 154.880 105.503 1.00 57.59  ? 87  GLY   B N   1 
ATOM   494  C CA  . GLY   A 1 87  ? 141.887 156.115 104.797 1.00 57.59  ? 87  GLY   B CA  1 
ATOM   495  C C   . GLY   A 1 87  ? 140.951 156.362 103.633 1.00 57.59  ? 87  GLY   B C   1 
ATOM   496  O O   . GLY   A 1 87  ? 141.291 157.081 102.695 1.00 57.59  ? 87  GLY   B O   1 
ATOM   497  N N   . ARG   A 1 93  ? 133.699 158.184 108.255 1.00 59.04  ? 93  ARG   B N   1 
ATOM   498  C CA  . ARG   A 1 93  ? 133.288 157.276 109.320 1.00 59.04  ? 93  ARG   B CA  1 
ATOM   499  C C   . ARG   A 1 93  ? 131.773 157.176 109.390 1.00 59.04  ? 93  ARG   B C   1 
ATOM   500  O O   . ARG   A 1 93  ? 131.203 156.956 110.458 1.00 59.04  ? 93  ARG   B O   1 
ATOM   501  C CB  . ARG   A 1 93  ? 133.853 157.739 110.663 1.00 59.04  ? 93  ARG   B CB  1 
ATOM   502  C CG  . ARG   A 1 93  ? 133.340 159.087 111.125 1.00 59.04  ? 93  ARG   B CG  1 
ATOM   503  C CD  . ARG   A 1 93  ? 134.418 159.855 111.847 1.00 59.04  ? 93  ARG   B CD  1 
ATOM   504  N NE  . ARG   A 1 93  ? 135.563 160.116 110.981 1.00 59.04  ? 93  ARG   B NE  1 
ATOM   505  C CZ  . ARG   A 1 93  ? 136.787 160.385 111.421 1.00 59.04  ? 93  ARG   B CZ  1 
ATOM   506  N NH1 . ARG   A 1 93  ? 137.032 160.431 112.723 1.00 59.04  ? 93  ARG   B NH1 1 
ATOM   507  N NH2 . ARG   A 1 93  ? 137.768 160.610 110.557 1.00 59.04  ? 93  ARG   B NH2 1 
ATOM   508  N N   . ARG   A 1 94  ? 131.120 157.313 108.240 1.00 56.71  ? 94  ARG   B N   1 
ATOM   509  C CA  . ARG   A 1 94  ? 129.669 157.439 108.240 1.00 56.71  ? 94  ARG   B CA  1 
ATOM   510  C C   . ARG   A 1 94  ? 128.982 156.086 108.377 1.00 56.71  ? 94  ARG   B C   1 
ATOM   511  O O   . ARG   A 1 94  ? 128.266 155.841 109.353 1.00 56.71  ? 94  ARG   B O   1 
ATOM   512  C CB  . ARG   A 1 94  ? 129.207 158.154 106.967 1.00 56.71  ? 94  ARG   B CB  1 
ATOM   513  N N   . LYS   A 1 95  ? 129.188 155.191 107.415 1.00 56.12  ? 95  LYS   B N   1 
ATOM   514  C CA  . LYS   A 1 95  ? 128.351 154.006 107.313 1.00 56.12  ? 95  LYS   B CA  1 
ATOM   515  C C   . LYS   A 1 95  ? 129.102 152.695 107.472 1.00 56.12  ? 95  LYS   B C   1 
ATOM   516  O O   . LYS   A 1 95  ? 128.471 151.679 107.781 1.00 56.12  ? 95  LYS   B O   1 
ATOM   517  C CB  . LYS   A 1 95  ? 127.605 154.006 105.969 1.00 56.12  ? 95  LYS   B CB  1 
ATOM   518  C CG  . LYS   A 1 95  ? 126.651 152.850 105.754 1.00 56.12  ? 95  LYS   B CG  1 
ATOM   519  C CD  . LYS   A 1 95  ? 125.538 152.867 106.788 1.00 56.12  ? 95  LYS   B CD  1 
ATOM   520  C CE  . LYS   A 1 95  ? 124.655 154.092 106.625 1.00 56.12  ? 95  LYS   B CE  1 
ATOM   521  N NZ  . LYS   A 1 95  ? 123.869 154.047 105.365 1.00 56.12  ? 95  LYS   B NZ  1 
ATOM   522  N N   . TRP   A 1 96  ? 130.417 152.685 107.316 1.00 55.11  ? 96  TRP   B N   1 
ATOM   523  C CA  . TRP   A 1 96  ? 131.189 151.481 107.562 1.00 55.11  ? 96  TRP   B CA  1 
ATOM   524  C C   . TRP   A 1 96  ? 131.585 151.326 109.016 1.00 55.11  ? 96  TRP   B C   1 
ATOM   525  O O   . TRP   A 1 96  ? 132.295 150.373 109.349 1.00 55.11  ? 96  TRP   B O   1 
ATOM   526  C CB  . TRP   A 1 96  ? 132.443 151.458 106.695 1.00 55.11  ? 96  TRP   B CB  1 
ATOM   527  C CG  . TRP   A 1 96  ? 133.224 152.707 106.707 1.00 55.11  ? 96  TRP   B CG  1 
ATOM   528  C CD1 . TRP   A 1 96  ? 133.215 153.678 105.761 1.00 55.11  ? 96  TRP   B CD1 1 
ATOM   529  C CD2 . TRP   A 1 96  ? 134.164 153.120 107.697 1.00 55.11  ? 96  TRP   B CD2 1 
ATOM   530  N NE1 . TRP   A 1 96  ? 134.082 154.679 106.103 1.00 55.11  ? 96  TRP   B NE1 1 
ATOM   531  C CE2 . TRP   A 1 96  ? 134.677 154.357 107.292 1.00 55.11  ? 96  TRP   B CE2 1 
ATOM   532  C CE3 . TRP   A 1 96  ? 134.616 152.565 108.894 1.00 55.11  ? 96  TRP   B CE3 1 
ATOM   533  C CZ2 . TRP   A 1 96  ? 135.619 155.046 108.034 1.00 55.11  ? 96  TRP   B CZ2 1 
ATOM   534  C CZ3 . TRP   A 1 96  ? 135.544 153.250 109.626 1.00 55.11  ? 96  TRP   B CZ3 1 
ATOM   535  C CH2 . TRP   A 1 96  ? 136.037 154.477 109.198 1.00 55.11  ? 96  TRP   B CH2 1 
ATOM   536  N N   . ILE   A 1 97  ? 131.155 152.238 109.888 1.00 52.60  ? 97  ILE   B N   1 
ATOM   537  C CA  . ILE   A 1 97  ? 131.521 152.146 111.293 1.00 52.60  ? 97  ILE   B CA  1 
ATOM   538  C C   . ILE   A 1 97  ? 130.828 150.998 111.995 1.00 52.60  ? 97  ILE   B C   1 
ATOM   539  O O   . ILE   A 1 97  ? 131.226 150.635 113.105 1.00 52.60  ? 97  ILE   B O   1 
ATOM   540  C CB  . ILE   A 1 97  ? 131.220 153.473 112.015 1.00 52.60  ? 97  ILE   B CB  1 
ATOM   541  C CG1 . ILE   A 1 97  ? 132.202 153.679 113.162 1.00 52.60  ? 97  ILE   B CG1 1 
ATOM   542  C CG2 . ILE   A 1 97  ? 129.781 153.504 112.518 1.00 52.60  ? 97  ILE   B CG2 1 
ATOM   543  C CD1 . ILE   A 1 97  ? 133.616 153.858 112.715 1.00 52.60  ? 97  ILE   B CD1 1 
ATOM   544  N N   . GLN   A 1 98  ? 129.808 150.409 111.379 1.00 54.32  ? 98  GLN   B N   1 
ATOM   545  C CA  . GLN   A 1 98  ? 129.160 149.252 111.974 1.00 54.32  ? 98  GLN   B CA  1 
ATOM   546  C C   . GLN   A 1 98  ? 129.992 147.989 111.838 1.00 54.32  ? 98  GLN   B C   1 
ATOM   547  O O   . GLN   A 1 98  ? 129.779 147.040 112.598 1.00 54.32  ? 98  GLN   B O   1 
ATOM   548  C CB  . GLN   A 1 98  ? 127.781 149.034 111.353 1.00 54.32  ? 98  GLN   B CB  1 
ATOM   549  C CG  . GLN   A 1 98  ? 127.800 148.720 109.883 1.00 54.32  ? 98  GLN   B CG  1 
ATOM   550  C CD  . GLN   A 1 98  ? 126.417 148.711 109.280 1.00 54.32  ? 98  GLN   B CD  1 
ATOM   551  O OE1 . GLN   A 1 98  ? 125.790 149.756 109.120 1.00 54.32  ? 98  GLN   B OE1 1 
ATOM   552  N NE2 . GLN   A 1 98  ? 125.929 147.526 108.941 1.00 54.32  ? 98  GLN   B NE2 1 
ATOM   553  N N   . CYS   A 1 99  ? 130.930 147.956 110.893 1.00 56.80  ? 99  CYS   B N   1 
ATOM   554  C CA  . CYS   A 1 99  ? 131.820 146.809 110.776 1.00 56.80  ? 99  CYS   B CA  1 
ATOM   555  C C   . CYS   A 1 99  ? 132.676 146.653 112.022 1.00 56.80  ? 99  CYS   B C   1 
ATOM   556  O O   . CYS   A 1 99  ? 132.917 145.533 112.483 1.00 56.80  ? 99  CYS   B O   1 
ATOM   557  C CB  . CYS   A 1 99  ? 132.695 146.953 109.534 1.00 56.80  ? 99  CYS   B CB  1 
ATOM   558  S SG  . CYS   A 1 99  ? 131.775 147.289 108.022 1.00 56.80  ? 99  CYS   B SG  1 
ATOM   559  N N   . PHE   A 1 100 ? 133.137 147.762 112.585 1.00 50.63  ? 100 PHE   B N   1 
ATOM   560  C CA  . PHE   A 1 100 ? 133.965 147.749 113.786 1.00 50.63  ? 100 PHE   B CA  1 
ATOM   561  C C   . PHE   A 1 100 ? 133.126 147.840 115.053 1.00 50.63  ? 100 PHE   B C   1 
ATOM   562  O O   . PHE   A 1 100 ? 133.345 148.691 115.907 1.00 50.63  ? 100 PHE   B O   1 
ATOM   563  C CB  . PHE   A 1 100 ? 134.970 148.885 113.721 1.00 50.63  ? 100 PHE   B CB  1 
ATOM   564  C CG  . PHE   A 1 100 ? 135.825 148.858 112.506 1.00 50.63  ? 100 PHE   B CG  1 
ATOM   565  C CD1 . PHE   A 1 100 ? 135.507 149.620 111.411 1.00 50.63  ? 100 PHE   B CD1 1 
ATOM   566  C CD2 . PHE   A 1 100 ? 136.954 148.073 112.461 1.00 50.63  ? 100 PHE   B CD2 1 
ATOM   567  C CE1 . PHE   A 1 100 ? 136.295 149.600 110.295 1.00 50.63  ? 100 PHE   B CE1 1 
ATOM   568  C CE2 . PHE   A 1 100 ? 137.744 148.050 111.346 1.00 50.63  ? 100 PHE   B CE2 1 
ATOM   569  C CZ  . PHE   A 1 100 ? 137.414 148.812 110.262 1.00 50.63  ? 100 PHE   B CZ  1 
ATOM   570  N N   . ASN   A 1 101 ? 132.148 146.954 115.171 1.00 48.62  ? 101 ASN   B N   1 
ATOM   571  C CA  . ASN   A 1 101 ? 131.299 146.891 116.346 1.00 48.62  ? 101 ASN   B CA  1 
ATOM   572  C C   . ASN   A 1 101 ? 131.856 145.975 117.420 1.00 48.62  ? 101 ASN   B C   1 
ATOM   573  O O   . ASN   A 1 101 ? 131.502 146.127 118.592 1.00 48.62  ? 101 ASN   B O   1 
ATOM   574  C CB  . ASN   A 1 101 ? 129.900 146.422 115.947 1.00 48.62  ? 101 ASN   B CB  1 
ATOM   575  C CG  . ASN   A 1 101 ? 129.037 146.080 117.131 1.00 48.62  ? 101 ASN   B CG  1 
ATOM   576  O OD1 . ASN   A 1 101 ? 128.972 144.927 117.555 1.00 48.62  ? 101 ASN   B OD1 1 
ATOM   577  N ND2 . ASN   A 1 101 ? 128.363 147.083 117.679 1.00 48.62  ? 101 ASN   B ND2 1 
ATOM   578  N N   . ASP   A 1 102 ? 132.728 145.042 117.058 1.00 46.45  ? 102 ASP   B N   1 
ATOM   579  C CA  . ASP   A 1 102 ? 133.267 144.073 117.999 1.00 46.45  ? 102 ASP   B CA  1 
ATOM   580  C C   . ASP   A 1 102 ? 134.693 144.387 118.429 1.00 46.45  ? 102 ASP   B C   1 
ATOM   581  O O   . ASP   A 1 102 ? 135.306 143.579 119.129 1.00 46.45  ? 102 ASP   B O   1 
ATOM   582  C CB  . ASP   A 1 102 ? 133.204 142.670 117.398 1.00 46.45  ? 102 ASP   B CB  1 
ATOM   583  N N   . VAL   A 1 103 ? 135.235 145.540 118.036 1.00 42.72  ? 103 VAL   B N   1 
ATOM   584  C CA  . VAL   A 1 103 ? 136.594 145.872 118.434 1.00 42.72  ? 103 VAL   B CA  1 
ATOM   585  C C   . VAL   A 1 103 ? 136.662 146.080 119.938 1.00 42.72  ? 103 VAL   B C   1 
ATOM   586  O O   . VAL   A 1 103 ? 135.661 146.327 120.615 1.00 42.72  ? 103 VAL   B O   1 
ATOM   587  C CB  . VAL   A 1 103 ? 137.119 147.108 117.689 1.00 42.72  ? 103 VAL   B CB  1 
ATOM   588  C CG1 . VAL   A 1 103 ? 137.448 146.774 116.257 1.00 42.72  ? 103 VAL   B CG1 1 
ATOM   589  C CG2 . VAL   A 1 103 ? 136.111 148.220 117.751 1.00 42.72  ? 103 VAL   B CG2 1 
ATOM   590  N N   . THR   A 1 104 ? 137.878 145.971 120.467 1.00 42.08  ? 104 THR   B N   1 
ATOM   591  C CA  . THR   A 1 104 ? 138.086 146.184 121.892 1.00 42.08  ? 104 THR   B CA  1 
ATOM   592  C C   . THR   A 1 104 ? 138.032 147.664 122.250 1.00 42.08  ? 104 THR   B C   1 
ATOM   593  O O   . THR   A 1 104 ? 137.407 148.040 123.247 1.00 42.08  ? 104 THR   B O   1 
ATOM   594  C CB  . THR   A 1 104 ? 139.414 145.568 122.320 1.00 42.08  ? 104 THR   B CB  1 
ATOM   595  O OG1 . THR   A 1 104 ? 139.451 144.199 121.912 1.00 42.08  ? 104 THR   B OG1 1 
ATOM   596  C CG2 . THR   A 1 104 ? 139.567 145.639 123.812 1.00 42.08  ? 104 THR   B CG2 1 
ATOM   597  N N   . ALA   A 1 105 ? 138.648 148.521 121.440 1.00 36.71  ? 105 ALA   B N   1 
ATOM   598  C CA  . ALA   A 1 105 ? 138.723 149.932 121.775 1.00 36.71  ? 105 ALA   B CA  1 
ATOM   599  C C   . ALA   A 1 105 ? 139.040 150.744 120.535 1.00 36.71  ? 105 ALA   B C   1 
ATOM   600  O O   . ALA   A 1 105 ? 139.645 150.246 119.584 1.00 36.71  ? 105 ALA   B O   1 
ATOM   601  C CB  . ALA   A 1 105 ? 139.773 150.181 122.850 1.00 36.71  ? 105 ALA   B CB  1 
ATOM   602  N N   . ILE   A 1 106 ? 138.630 152.008 120.560 1.00 34.86  ? 106 ILE   B N   1 
ATOM   603  C CA  . ILE   A 1 106 ? 138.908 152.956 119.489 1.00 34.86  ? 106 ILE   B CA  1 
ATOM   604  C C   . ILE   A 1 106 ? 139.914 153.975 119.989 1.00 34.86  ? 106 ILE   B C   1 
ATOM   605  O O   . ILE   A 1 106 ? 139.693 154.624 121.015 1.00 34.86  ? 106 ILE   B O   1 
ATOM   606  C CB  . ILE   A 1 106 ? 137.636 153.655 118.984 1.00 34.86  ? 106 ILE   B CB  1 
ATOM   607  C CG1 . ILE   A 1 106 ? 136.691 152.657 118.336 1.00 34.86  ? 106 ILE   B CG1 1 
ATOM   608  C CG2 . ILE   A 1 106 ? 137.982 154.729 118.002 1.00 34.86  ? 106 ILE   B CG2 1 
ATOM   609  C CD1 . ILE   A 1 106 ? 135.349 153.210 118.041 1.00 34.86  ? 106 ILE   B CD1 1 
ATOM   610  N N   . ILE   A 1 107 ? 141.011 154.115 119.267 1.00 36.32  ? 107 ILE   B N   1 
ATOM   611  C CA  . ILE   A 1 107 ? 142.026 155.105 119.586 1.00 36.32  ? 107 ILE   B CA  1 
ATOM   612  C C   . ILE   A 1 107 ? 141.680 156.377 118.835 1.00 36.32  ? 107 ILE   B C   1 
ATOM   613  O O   . ILE   A 1 107 ? 141.533 156.366 117.609 1.00 36.32  ? 107 ILE   B O   1 
ATOM   614  C CB  . ILE   A 1 107 ? 143.427 154.609 119.212 1.00 36.32  ? 107 ILE   B CB  1 
ATOM   615  C CG1 . ILE   A 1 107 ? 143.677 153.243 119.830 1.00 36.32  ? 107 ILE   B CG1 1 
ATOM   616  C CG2 . ILE   A 1 107 ? 144.468 155.578 119.680 1.00 36.32  ? 107 ILE   B CG2 1 
ATOM   617  C CD1 . ILE   A 1 107 ? 145.063 152.748 119.628 1.00 36.32  ? 107 ILE   B CD1 1 
ATOM   618  N N   . PHE   A 1 108 ? 141.546 157.469 119.566 1.00 38.72  ? 108 PHE   B N   1 
ATOM   619  C CA  . PHE   A 1 108 ? 141.203 158.757 118.996 1.00 38.72  ? 108 PHE   B CA  1 
ATOM   620  C C   . PHE   A 1 108 ? 142.379 159.705 119.174 1.00 38.72  ? 108 PHE   B C   1 
ATOM   621  O O   . PHE   A 1 108 ? 142.864 159.891 120.290 1.00 38.72  ? 108 PHE   B O   1 
ATOM   622  C CB  . PHE   A 1 108 ? 139.949 159.313 119.663 1.00 38.72  ? 108 PHE   B CB  1 
ATOM   623  C CG  . PHE   A 1 108 ? 139.175 160.244 118.800 1.00 38.72  ? 108 PHE   B CG  1 
ATOM   624  C CD1 . PHE   A 1 108 ? 138.117 159.795 118.056 1.00 38.72  ? 108 PHE   B CD1 1 
ATOM   625  C CD2 . PHE   A 1 108 ? 139.521 161.575 118.719 1.00 38.72  ? 108 PHE   B CD2 1 
ATOM   626  C CE1 . PHE   A 1 108 ? 137.420 160.656 117.255 1.00 38.72  ? 108 PHE   B CE1 1 
ATOM   627  C CE2 . PHE   A 1 108 ? 138.825 162.432 117.920 1.00 38.72  ? 108 PHE   B CE2 1 
ATOM   628  C CZ  . PHE   A 1 108 ? 137.776 161.974 117.189 1.00 38.72  ? 108 PHE   B CZ  1 
ATOM   629  N N   . VAL   A 1 109 ? 142.835 160.297 118.080 1.00 42.37  ? 109 VAL   B N   1 
ATOM   630  C CA  . VAL   A 1 109 ? 143.987 161.187 118.086 1.00 42.37  ? 109 VAL   B CA  1 
ATOM   631  C C   . VAL   A 1 109 ? 143.515 162.600 117.771 1.00 42.37  ? 109 VAL   B C   1 
ATOM   632  O O   . VAL   A 1 109 ? 142.957 162.850 116.697 1.00 42.37  ? 109 VAL   B O   1 
ATOM   633  C CB  . VAL   A 1 109 ? 145.050 160.729 117.086 1.00 42.37  ? 109 VAL   B CB  1 
ATOM   634  C CG1 . VAL   A 1 109 ? 146.103 161.775 116.958 1.00 42.37  ? 109 VAL   B CG1 1 
ATOM   635  C CG2 . VAL   A 1 109 ? 145.648 159.428 117.539 1.00 42.37  ? 109 VAL   B CG2 1 
ATOM   636  N N   . VAL   A 1 110 ? 143.744 163.520 118.702 1.00 49.70  ? 110 VAL   B N   1 
ATOM   637  C CA  . VAL   A 1 110 ? 143.385 164.923 118.552 1.00 49.70  ? 110 VAL   B CA  1 
ATOM   638  C C   . VAL   A 1 110 ? 144.633 165.757 118.777 1.00 49.70  ? 110 VAL   B C   1 
ATOM   639  O O   . VAL   A 1 110 ? 145.363 165.537 119.748 1.00 49.70  ? 110 VAL   B O   1 
ATOM   640  C CB  . VAL   A 1 110 ? 142.284 165.341 119.538 1.00 49.70  ? 110 VAL   B CB  1 
ATOM   641  C CG1 . VAL   A 1 110 ? 142.252 166.838 119.683 1.00 49.70  ? 110 VAL   B CG1 1 
ATOM   642  C CG2 . VAL   A 1 110 ? 140.947 164.836 119.072 1.00 49.70  ? 110 VAL   B CG2 1 
ATOM   643  N N   . ASP   A 1 111 ? 144.881 166.706 117.882 1.00 63.03  ? 111 ASP   B N   1 
ATOM   644  C CA  . ASP   A 1 111 ? 146.044 167.580 117.971 1.00 63.03  ? 111 ASP   B CA  1 
ATOM   645  C C   . ASP   A 1 111 ? 145.647 168.768 118.841 1.00 63.03  ? 111 ASP   B C   1 
ATOM   646  O O   . ASP   A 1 111 ? 144.798 169.573 118.455 1.00 63.03  ? 111 ASP   B O   1 
ATOM   647  C CB  . ASP   A 1 111 ? 146.490 168.000 116.571 1.00 63.03  ? 111 ASP   B CB  1 
ATOM   648  C CG  . ASP   A 1 111 ? 147.556 169.099 116.561 1.00 63.03  ? 111 ASP   B CG  1 
ATOM   649  O OD1 . ASP   A 1 111 ? 147.616 169.954 117.464 1.00 63.03  ? 111 ASP   B OD1 1 
ATOM   650  O OD2 . ASP   A 1 111 ? 148.354 169.108 115.600 1.00 63.03  ? 111 ASP   B OD2 1 
ATOM   651  N N   . SER   A 1 112 ? 146.259 168.871 120.019 1.00 64.01  ? 112 SER   B N   1 
ATOM   652  C CA  . SER   A 1 112 ? 145.946 169.953 120.939 1.00 64.01  ? 112 SER   B CA  1 
ATOM   653  C C   . SER   A 1 112 ? 146.615 171.263 120.560 1.00 64.01  ? 112 SER   B C   1 
ATOM   654  O O   . SER   A 1 112 ? 146.174 172.317 121.024 1.00 64.01  ? 112 SER   B O   1 
ATOM   655  C CB  . SER   A 1 112 ? 146.352 169.564 122.360 1.00 64.01  ? 112 SER   B CB  1 
ATOM   656  O OG  . SER   A 1 112 ? 147.757 169.417 122.463 1.00 64.01  ? 112 SER   B OG  1 
ATOM   657  N N   . SER   A 1 113 ? 147.650 171.223 119.720 1.00 68.48  ? 113 SER   B N   1 
ATOM   658  C CA  . SER   A 1 113 ? 148.416 172.427 119.415 1.00 68.48  ? 113 SER   B CA  1 
ATOM   659  C C   . SER   A 1 113 ? 147.575 173.457 118.669 1.00 68.48  ? 113 SER   B C   1 
ATOM   660  O O   . SER   A 1 113 ? 147.518 174.627 119.062 1.00 68.48  ? 113 SER   B O   1 
ATOM   661  C CB  . SER   A 1 113 ? 149.659 172.059 118.609 1.00 68.48  ? 113 SER   B CB  1 
ATOM   662  O OG  . SER   A 1 113 ? 149.315 171.708 117.281 1.00 68.48  ? 113 SER   B OG  1 
ATOM   663  N N   . ASP   A 1 114 ? 146.918 173.048 117.585 1.00 69.97  ? 114 ASP   B N   1 
ATOM   664  C CA  . ASP   A 1 114 ? 146.067 173.955 116.827 1.00 69.97  ? 114 ASP   B CA  1 
ATOM   665  C C   . ASP   A 1 114 ? 144.745 174.160 117.553 1.00 69.97  ? 114 ASP   B C   1 
ATOM   666  O O   . ASP   A 1 114 ? 144.207 173.232 118.163 1.00 69.97  ? 114 ASP   B O   1 
ATOM   667  C CB  . ASP   A 1 114 ? 145.815 173.426 115.415 1.00 69.97  ? 114 ASP   B CB  1 
ATOM   668  C CG  . ASP   A 1 114 ? 145.356 171.983 115.399 1.00 69.97  ? 114 ASP   B CG  1 
ATOM   669  O OD1 . ASP   A 1 114 ? 145.363 171.341 116.467 1.00 69.97  ? 114 ASP   B OD1 1 
ATOM   670  O OD2 . ASP   A 1 114 ? 144.986 171.490 114.313 1.00 69.97  ? 114 ASP   B OD2 1 
ATOM   671  N N   . TYR   A 1 115 ? 144.224 175.387 117.487 1.00 70.74  ? 115 TYR   B N   1 
ATOM   672  C CA  . TYR   A 1 115 ? 143.028 175.745 118.235 1.00 70.74  ? 115 TYR   B CA  1 
ATOM   673  C C   . TYR   A 1 115 ? 141.804 176.000 117.371 1.00 70.74  ? 115 TYR   B C   1 
ATOM   674  O O   . TYR   A 1 115 ? 140.688 175.968 117.895 1.00 70.74  ? 115 TYR   B O   1 
ATOM   675  C CB  . TYR   A 1 115 ? 143.286 176.987 119.096 1.00 70.74  ? 115 TYR   B CB  1 
ATOM   676  C CG  . TYR   A 1 115 ? 144.491 176.879 119.994 1.00 70.74  ? 115 TYR   B CG  1 
ATOM   677  C CD1 . TYR   A 1 115 ? 144.760 175.715 120.687 1.00 70.74  ? 115 TYR   B CD1 1 
ATOM   678  C CD2 . TYR   A 1 115 ? 145.353 177.944 120.149 1.00 70.74  ? 115 TYR   B CD2 1 
ATOM   679  C CE1 . TYR   A 1 115 ? 145.859 175.615 121.512 1.00 70.74  ? 115 TYR   B CE1 1 
ATOM   680  C CE2 . TYR   A 1 115 ? 146.455 177.858 120.965 1.00 70.74  ? 115 TYR   B CE2 1 
ATOM   681  C CZ  . TYR   A 1 115 ? 146.707 176.691 121.646 1.00 70.74  ? 115 TYR   B CZ  1 
ATOM   682  O OH  . TYR   A 1 115 ? 147.809 176.606 122.465 1.00 70.74  ? 115 TYR   B OH  1 
ATOM   683  N N   . ASN   A 1 116 ? 141.973 176.258 116.080 1.00 67.87  ? 116 ASN   B N   1 
ATOM   684  C CA  . ASN   A 1 116 ? 140.820 176.435 115.211 1.00 67.87  ? 116 ASN   B CA  1 
ATOM   685  C C   . ASN   A 1 116 ? 140.273 175.117 114.693 1.00 67.87  ? 116 ASN   B C   1 
ATOM   686  O O   . ASN   A 1 116 ? 139.186 175.103 114.106 1.00 67.87  ? 116 ASN   B O   1 
ATOM   687  C CB  . ASN   A 1 116 ? 141.183 177.337 114.033 1.00 67.87  ? 116 ASN   B CB  1 
ATOM   688  N N   . ARG   A 1 117 ? 140.997 174.018 114.886 1.00 66.80  ? 117 ARG   B N   1 
ATOM   689  C CA  . ARG   A 1 117 ? 140.537 172.699 114.490 1.00 66.80  ? 117 ARG   B CA  1 
ATOM   690  C C   . ARG   A 1 117 ? 140.049 171.873 115.666 1.00 66.80  ? 117 ARG   B C   1 
ATOM   691  O O   . ARG   A 1 117 ? 139.471 170.796 115.458 1.00 66.80  ? 117 ARG   B O   1 
ATOM   692  C CB  . ARG   A 1 117 ? 141.658 171.949 113.764 1.00 66.80  ? 117 ARG   B CB  1 
ATOM   693  C CG  . ARG   A 1 117 ? 141.953 172.487 112.379 1.00 66.80  ? 117 ARG   B CG  1 
ATOM   694  C CD  . ARG   A 1 117 ? 142.978 171.636 111.656 1.00 66.80  ? 117 ARG   B CD  1 
ATOM   695  N NE  . ARG   A 1 117 ? 142.405 170.389 111.162 1.00 66.80  ? 117 ARG   B NE  1 
ATOM   696  C CZ  . ARG   A 1 117 ? 141.674 170.286 110.056 1.00 66.80  ? 117 ARG   B CZ  1 
ATOM   697  N NH1 . ARG   A 1 117 ? 141.193 169.108 109.684 1.00 66.80  ? 117 ARG   B NH1 1 
ATOM   698  N NH2 . ARG   A 1 117 ? 141.427 171.361 109.319 1.00 66.80  ? 117 ARG   B NH2 1 
ATOM   699  N N   . LEU   A 1 118 ? 140.263 172.351 116.891 1.00 62.13  ? 118 LEU   B N   1 
ATOM   700  C CA  . LEU   A 1 118 ? 139.832 171.600 118.061 1.00 62.13  ? 118 LEU   B CA  1 
ATOM   701  C C   . LEU   A 1 118 ? 138.322 171.450 118.104 1.00 62.13  ? 118 LEU   B C   1 
ATOM   702  O O   . LEU   A 1 118 ? 137.818 170.441 118.599 1.00 62.13  ? 118 LEU   B O   1 
ATOM   703  C CB  . LEU   A 1 118 ? 140.322 172.279 119.335 1.00 62.13  ? 118 LEU   B CB  1 
ATOM   704  C CG  . LEU   A 1 118 ? 141.699 171.875 119.837 1.00 62.13  ? 118 LEU   B CG  1 
ATOM   705  C CD1 . LEU   A 1 118 ? 142.065 172.696 121.058 1.00 62.13  ? 118 LEU   B CD1 1 
ATOM   706  C CD2 . LEU   A 1 118 ? 141.727 170.398 120.159 1.00 62.13  ? 118 LEU   B CD2 1 
ATOM   707  N N   . GLN   A 1 119 ? 137.577 172.440 117.608 1.00 60.93  ? 119 GLN   B N   1 
ATOM   708  C CA  . GLN   A 1 119 ? 136.123 172.334 117.637 1.00 60.93  ? 119 GLN   B CA  1 
ATOM   709  C C   . GLN   A 1 119 ? 135.627 171.281 116.654 1.00 60.93  ? 119 GLN   B C   1 
ATOM   710  O O   . GLN   A 1 119 ? 134.685 170.535 116.952 1.00 60.93  ? 119 GLN   B O   1 
ATOM   711  C CB  . GLN   A 1 119 ? 135.495 173.693 117.348 1.00 60.93  ? 119 GLN   B CB  1 
ATOM   712  C CG  . GLN   A 1 119 ? 133.995 173.731 117.538 1.00 60.93  ? 119 GLN   B CG  1 
ATOM   713  C CD  . GLN   A 1 119 ? 133.574 173.370 118.942 1.00 60.93  ? 119 GLN   B CD  1 
ATOM   714  O OE1 . GLN   A 1 119 ? 134.223 173.751 119.915 1.00 60.93  ? 119 GLN   B OE1 1 
ATOM   715  N NE2 . GLN   A 1 119 ? 132.475 172.637 119.058 1.00 60.93  ? 119 GLN   B NE2 1 
ATOM   716  N N   . GLU   A 1 120 ? 136.260 171.190 115.483 1.00 58.75  ? 120 GLU   B N   1 
ATOM   717  C CA  . GLU   A 1 120 ? 135.960 170.093 114.572 1.00 58.75  ? 120 GLU   B CA  1 
ATOM   718  C C   . GLU   A 1 120 ? 136.310 168.754 115.206 1.00 58.75  ? 120 GLU   B C   1 
ATOM   719  O O   . GLU   A 1 120 ? 135.582 167.767 115.039 1.00 58.75  ? 120 GLU   B O   1 
ATOM   720  C CB  . GLU   A 1 120 ? 136.714 170.283 113.257 1.00 58.75  ? 120 GLU   B CB  1 
ATOM   721  N N   . ALA   A 1 121 ? 137.424 168.703 115.942 1.00 54.50  ? 121 ALA   B N   1 
ATOM   722  C CA  . ALA   A 1 121 ? 137.789 167.475 116.641 1.00 54.50  ? 121 ALA   B CA  1 
ATOM   723  C C   . ALA   A 1 121 ? 136.742 167.097 117.683 1.00 54.50  ? 121 ALA   B C   1 
ATOM   724  O O   . ALA   A 1 121 ? 136.370 165.923 117.799 1.00 54.50  ? 121 ALA   B O   1 
ATOM   725  C CB  . ALA   A 1 121 ? 139.161 167.630 117.287 1.00 54.50  ? 121 ALA   B CB  1 
ATOM   726  N N   . LEU   A 1 122 ? 136.252 168.074 118.449 1.00 53.08  ? 122 LEU   B N   1 
ATOM   727  C CA  . LEU   A 1 122 ? 135.208 167.791 119.430 1.00 53.08  ? 122 LEU   B CA  1 
ATOM   728  C C   . LEU   A 1 122 ? 133.933 167.302 118.762 1.00 53.08  ? 122 LEU   B C   1 
ATOM   729  O O   . LEU   A 1 122 ? 133.266 166.401 119.276 1.00 53.08  ? 122 LEU   B O   1 
ATOM   730  C CB  . LEU   A 1 122 ? 134.900 169.017 120.284 1.00 53.08  ? 122 LEU   B CB  1 
ATOM   731  C CG  . LEU   A 1 122 ? 135.599 169.204 121.627 1.00 53.08  ? 122 LEU   B CG  1 
ATOM   732  C CD1 . LEU   A 1 122 ? 137.027 169.658 121.466 1.00 53.08  ? 122 LEU   B CD1 1 
ATOM   733  C CD2 . LEU   A 1 122 ? 134.826 170.184 122.484 1.00 53.08  ? 122 LEU   B CD2 1 
ATOM   734  N N   . ASN   A 1 123 ? 133.560 167.900 117.633 1.00 53.12  ? 123 ASN   B N   1 
ATOM   735  C CA  . ASN   A 1 123 ? 132.348 167.462 116.952 1.00 53.12  ? 123 ASN   B CA  1 
ATOM   736  C C   . ASN   A 1 123 ? 132.497 166.046 116.410 1.00 53.12  ? 123 ASN   B C   1 
ATOM   737  O O   . ASN   A 1 123 ? 131.563 165.240 116.495 1.00 53.12  ? 123 ASN   B O   1 
ATOM   738  C CB  . ASN   A 1 123 ? 131.996 168.439 115.828 1.00 53.12  ? 123 ASN   B CB  1 
ATOM   739  C CG  . ASN   A 1 123 ? 131.395 169.737 116.346 1.00 53.12  ? 123 ASN   B CG  1 
ATOM   740  O OD1 . ASN   A 1 123 ? 131.055 169.851 117.521 1.00 53.12  ? 123 ASN   B OD1 1 
ATOM   741  N ND2 . ASN   A 1 123 ? 131.265 170.720 115.466 1.00 53.12  ? 123 ASN   B ND2 1 
ATOM   742  N N   . ASP   A 1 124 ? 133.665 165.720 115.855 1.00 51.61  ? 124 ASP   B N   1 
ATOM   743  C CA  . ASP   A 1 124 ? 133.909 164.357 115.392 1.00 51.61  ? 124 ASP   B CA  1 
ATOM   744  C C   . ASP   A 1 124 ? 133.857 163.365 116.547 1.00 51.61  ? 124 ASP   B C   1 
ATOM   745  O O   . ASP   A 1 124 ? 133.268 162.279 116.428 1.00 51.61  ? 124 ASP   B O   1 
ATOM   746  C CB  . ASP   A 1 124 ? 135.257 164.283 114.684 1.00 51.61  ? 124 ASP   B CB  1 
ATOM   747  C CG  . ASP   A 1 124 ? 135.326 163.148 113.693 1.00 51.61  ? 124 ASP   B CG  1 
ATOM   748  O OD1 . ASP   A 1 124 ? 134.455 162.258 113.762 1.00 51.61  ? 124 ASP   B OD1 1 
ATOM   749  O OD2 . ASP   A 1 124 ? 136.247 163.143 112.849 1.00 51.61  ? 124 ASP   B OD2 1 
ATOM   750  N N   . PHE   A 1 125 ? 134.462 163.727 117.678 1.00 42.61  ? 125 PHE   B N   1 
ATOM   751  C CA  . PHE   A 1 125 ? 134.416 162.868 118.851 1.00 42.61  ? 125 PHE   B CA  1 
ATOM   752  C C   . PHE   A 1 125 ? 132.992 162.676 119.333 1.00 42.61  ? 125 PHE   B C   1 
ATOM   753  O O   . PHE   A 1 125 ? 132.610 161.576 119.738 1.00 42.61  ? 125 PHE   B O   1 
ATOM   754  C CB  . PHE   A 1 125 ? 135.271 163.456 119.966 1.00 42.61  ? 125 PHE   B CB  1 
ATOM   755  C CG  . PHE   A 1 125 ? 135.324 162.602 121.183 1.00 42.61  ? 125 PHE   B CG  1 
ATOM   756  C CD1 . PHE   A 1 125 ? 136.073 161.456 121.197 1.00 42.61  ? 125 PHE   B CD1 1 
ATOM   757  C CD2 . PHE   A 1 125 ? 134.604 162.926 122.298 1.00 42.61  ? 125 PHE   B CD2 1 
ATOM   758  C CE1 . PHE   A 1 125 ? 136.112 160.671 122.306 1.00 42.61  ? 125 PHE   B CE1 1 
ATOM   759  C CE2 . PHE   A 1 125 ? 134.641 162.138 123.396 1.00 42.61  ? 125 PHE   B CE2 1 
ATOM   760  C CZ  . PHE   A 1 125 ? 135.397 161.017 123.402 1.00 42.61  ? 125 PHE   B CZ  1 
ATOM   761  N N   . LYS   A 1 126 ? 132.196 163.741 119.318 1.00 44.73  ? 126 LYS   B N   1 
ATOM   762  C CA  . LYS   A 1 126 ? 130.820 163.650 119.776 1.00 44.73  ? 126 LYS   B CA  1 
ATOM   763  C C   . LYS   A 1 126 ? 129.982 162.800 118.842 1.00 44.73  ? 126 LYS   B C   1 
ATOM   764  O O   . LYS   A 1 126 ? 129.049 162.126 119.286 1.00 44.73  ? 126 LYS   B O   1 
ATOM   765  C CB  . LYS   A 1 126 ? 130.232 165.049 119.907 1.00 44.73  ? 126 LYS   B CB  1 
ATOM   766  C CG  . LYS   A 1 126 ? 128.891 165.101 120.565 1.00 44.73  ? 126 LYS   B CG  1 
ATOM   767  C CD  . LYS   A 1 126 ? 128.351 166.511 120.560 1.00 44.73  ? 126 LYS   B CD  1 
ATOM   768  C CE  . LYS   A 1 126 ? 129.189 167.413 121.443 1.00 44.73  ? 126 LYS   B CE  1 
ATOM   769  N NZ  . LYS   A 1 126 ? 129.360 168.767 120.855 1.00 44.73  ? 126 LYS   B NZ  1 
ATOM   770  N N   . SER   A 1 127 ? 130.292 162.822 117.551 1.00 44.07  ? 127 SER   B N   1 
ATOM   771  C CA  . SER   A 1 127 ? 129.623 161.920 116.625 1.00 44.07  ? 127 SER   B CA  1 
ATOM   772  C C   . SER   A 1 127 ? 129.953 160.472 116.942 1.00 44.07  ? 127 SER   B C   1 
ATOM   773  O O   . SER   A 1 127 ? 129.059 159.626 117.039 1.00 44.07  ? 127 SER   B O   1 
ATOM   774  C CB  . SER   A 1 127 ? 130.024 162.254 115.193 1.00 44.07  ? 127 SER   B CB  1 
ATOM   775  O OG  . SER   A 1 127 ? 129.510 161.290 114.293 1.00 44.07  ? 127 SER   B OG  1 
ATOM   776  N N   . ILE   A 1 128 ? 131.240 160.166 117.107 1.00 44.45  ? 128 ILE   B N   1 
ATOM   777  C CA  . ILE   A 1 128 ? 131.636 158.777 117.320 1.00 44.45  ? 128 ILE   B CA  1 
ATOM   778  C C   . ILE   A 1 128 ? 131.175 158.263 118.681 1.00 44.45  ? 128 ILE   B C   1 
ATOM   779  O O   . ILE   A 1 128 ? 130.855 157.078 118.827 1.00 44.45  ? 128 ILE   B O   1 
ATOM   780  C CB  . ILE   A 1 128 ? 133.152 158.636 117.126 1.00 44.45  ? 128 ILE   B CB  1 
ATOM   781  C CG1 . ILE   A 1 128 ? 133.510 158.985 115.688 1.00 44.45  ? 128 ILE   B CG1 1 
ATOM   782  C CG2 . ILE   A 1 128 ? 133.618 157.239 117.438 1.00 44.45  ? 128 ILE   B CG2 1 
ATOM   783  C CD1 . ILE   A 1 128 ? 134.974 159.133 115.440 1.00 44.45  ? 128 ILE   B CD1 1 
ATOM   784  N N   . TRP   A 1 129 ? 131.120 159.127 119.691 1.00 43.18  ? 129 TRP   B N   1 
ATOM   785  C CA  . TRP   A 1 129 ? 130.702 158.705 121.023 1.00 43.18  ? 129 TRP   B CA  1 
ATOM   786  C C   . TRP   A 1 129 ? 129.240 158.287 121.049 1.00 43.18  ? 129 TRP   B C   1 
ATOM   787  O O   . TRP   A 1 129 ? 128.890 157.253 121.628 1.00 43.18  ? 129 TRP   B O   1 
ATOM   788  C CB  . TRP   A 1 129 ? 130.945 159.833 122.018 1.00 43.18  ? 129 TRP   B CB  1 
ATOM   789  C CG  . TRP   A 1 129 ? 130.778 159.446 123.441 1.00 43.18  ? 129 TRP   B CG  1 
ATOM   790  C CD1 . TRP   A 1 129 ? 129.759 159.792 124.261 1.00 43.18  ? 129 TRP   B CD1 1 
ATOM   791  C CD2 . TRP   A 1 129 ? 131.671 158.656 124.222 1.00 43.18  ? 129 TRP   B CD2 1 
ATOM   792  N NE1 . TRP   A 1 129 ? 129.950 159.262 125.504 1.00 43.18  ? 129 TRP   B NE1 1 
ATOM   793  C CE2 . TRP   A 1 129 ? 131.120 158.554 125.504 1.00 43.18  ? 129 TRP   B CE2 1 
ATOM   794  C CE3 . TRP   A 1 129 ? 132.880 158.019 123.958 1.00 43.18  ? 129 TRP   B CE3 1 
ATOM   795  C CZ2 . TRP   A 1 129 ? 131.733 157.843 126.518 1.00 43.18  ? 129 TRP   B CZ2 1 
ATOM   796  C CZ3 . TRP   A 1 129 ? 133.484 157.316 124.960 1.00 43.18  ? 129 TRP   B CZ3 1 
ATOM   797  C CH2 . TRP   A 1 129 ? 132.915 157.232 126.226 1.00 43.18  ? 129 TRP   B CH2 1 
ATOM   798  N N   . ASN   A 1 130 ? 128.367 159.078 120.428 1.00 42.95  ? 130 ASN   B N   1 
ATOM   799  C CA  . ASN   A 1 130 ? 126.929 158.855 120.489 1.00 42.95  ? 130 ASN   B CA  1 
ATOM   800  C C   . ASN   A 1 130 ? 126.410 158.081 119.285 1.00 42.95  ? 130 ASN   B C   1 
ATOM   801  O O   . ASN   A 1 130 ? 125.276 158.298 118.850 1.00 42.95  ? 130 ASN   B O   1 
ATOM   802  C CB  . ASN   A 1 130 ? 126.195 160.186 120.621 1.00 42.95  ? 130 ASN   B CB  1 
ATOM   803  C CG  . ASN   A 1 130 ? 126.697 161.015 121.778 1.00 42.95  ? 130 ASN   B CG  1 
ATOM   804  O OD1 . ASN   A 1 130 ? 127.057 160.484 122.824 1.00 42.95  ? 130 ASN   B OD1 1 
ATOM   805  N ND2 . ASN   A 1 130 ? 126.720 162.325 121.599 1.00 42.95  ? 130 ASN   B ND2 1 
ATOM   806  N N   . ASN   A 1 131 ? 127.215 157.183 118.736 1.00 45.17  ? 131 ASN   B N   1 
ATOM   807  C CA  . ASN   A 1 131 ? 126.804 156.371 117.605 1.00 45.17  ? 131 ASN   B CA  1 
ATOM   808  C C   . ASN   A 1 131 ? 126.095 155.115 118.091 1.00 45.17  ? 131 ASN   B C   1 
ATOM   809  O O   . ASN   A 1 131 ? 126.471 154.532 119.110 1.00 45.17  ? 131 ASN   B O   1 
ATOM   810  C CB  . ASN   A 1 131 ? 128.009 156.000 116.748 1.00 45.17  ? 131 ASN   B CB  1 
ATOM   811  C CG  . ASN   A 1 131 ? 127.640 155.750 115.312 1.00 45.17  ? 131 ASN   B CG  1 
ATOM   812  O OD1 . ASN   A 1 131 ? 126.592 155.179 115.020 1.00 45.17  ? 131 ASN   B OD1 1 
ATOM   813  N ND2 . ASN   A 1 131 ? 128.493 156.184 114.400 1.00 45.17  ? 131 ASN   B ND2 1 
ATOM   814  N N   . ARG   A 1 132 ? 125.065 154.706 117.349 1.00 45.83  ? 132 ARG   B N   1 
ATOM   815  C CA  . ARG   A 1 132 ? 124.208 153.613 117.795 1.00 45.83  ? 132 ARG   B CA  1 
ATOM   816  C C   . ARG   A 1 132 ? 124.982 152.313 117.917 1.00 45.83  ? 132 ARG   B C   1 
ATOM   817  O O   . ARG   A 1 132 ? 124.778 151.546 118.863 1.00 45.83  ? 132 ARG   B O   1 
ATOM   818  C CB  . ARG   A 1 132 ? 123.040 153.441 116.827 1.00 45.83  ? 132 ARG   B CB  1 
ATOM   819  N N   . TRP   A 1 133 ? 125.873 152.047 116.967 1.00 48.73  ? 133 TRP   B N   1 
ATOM   820  C CA  . TRP   A 1 133 ? 126.590 150.784 116.914 1.00 48.73  ? 133 TRP   B CA  1 
ATOM   821  C C   . TRP   A 1 133 ? 127.829 150.758 117.790 1.00 48.73  ? 133 TRP   B C   1 
ATOM   822  O O   . TRP   A 1 133 ? 128.405 149.688 117.988 1.00 48.73  ? 133 TRP   B O   1 
ATOM   823  C CB  . TRP   A 1 133 ? 126.977 150.480 115.472 1.00 48.73  ? 133 TRP   B CB  1 
ATOM   824  C CG  . TRP   A 1 133 ? 125.840 150.548 114.530 1.00 48.73  ? 133 TRP   B CG  1 
ATOM   825  C CD1 . TRP   A 1 133 ? 125.729 151.360 113.446 1.00 48.73  ? 133 TRP   B CD1 1 
ATOM   826  C CD2 . TRP   A 1 133 ? 124.645 149.767 114.571 1.00 48.73  ? 133 TRP   B CD2 1 
ATOM   827  N NE1 . TRP   A 1 133 ? 124.540 151.137 112.809 1.00 48.73  ? 133 TRP   B NE1 1 
ATOM   828  C CE2 . TRP   A 1 133 ? 123.855 150.161 113.482 1.00 48.73  ? 133 TRP   B CE2 1 
ATOM   829  C CE3 . TRP   A 1 133 ? 124.167 148.772 115.424 1.00 48.73  ? 133 TRP   B CE3 1 
ATOM   830  C CZ2 . TRP   A 1 133 ? 122.613 149.599 113.225 1.00 48.73  ? 133 TRP   B CZ2 1 
ATOM   831  C CZ3 . TRP   A 1 133 ? 122.941 148.218 115.170 1.00 48.73  ? 133 TRP   B CZ3 1 
ATOM   832  C CH2 . TRP   A 1 133 ? 122.174 148.629 114.080 1.00 48.73  ? 133 TRP   B CH2 1 
ATOM   833  N N   . LEU   A 1 134 ? 128.248 151.903 118.317 1.00 46.68  ? 134 LEU   B N   1 
ATOM   834  C CA  . LEU   A 1 134 ? 129.433 152.013 119.152 1.00 46.68  ? 134 LEU   B CA  1 
ATOM   835  C C   . LEU   A 1 134 ? 129.078 152.240 120.613 1.00 46.68  ? 134 LEU   B C   1 
ATOM   836  O O   . LEU   A 1 134 ? 129.892 152.775 121.368 1.00 46.68  ? 134 LEU   B O   1 
ATOM   837  C CB  . LEU   A 1 134 ? 130.324 153.145 118.650 1.00 46.68  ? 134 LEU   B CB  1 
ATOM   838  C CG  . LEU   A 1 134 ? 131.414 152.838 117.626 1.00 46.68  ? 134 LEU   B CG  1 
ATOM   839  C CD1 . LEU   A 1 134 ? 130.908 151.989 116.497 1.00 46.68  ? 134 LEU   B CD1 1 
ATOM   840  C CD2 . LEU   A 1 134 ? 131.976 154.120 117.080 1.00 46.68  ? 134 LEU   B CD2 1 
ATOM   841  N N   . ARG   A 1 135 ? 127.876 151.843 121.023 1.00 49.23  ? 135 ARG   B N   1 
ATOM   842  C CA  . ARG   A 1 135 ? 127.370 152.143 122.354 1.00 49.23  ? 135 ARG   B CA  1 
ATOM   843  C C   . ARG   A 1 135 ? 128.018 151.301 123.439 1.00 49.23  ? 135 ARG   B C   1 
ATOM   844  O O   . ARG   A 1 135 ? 127.758 151.543 124.621 1.00 49.23  ? 135 ARG   B O   1 
ATOM   845  C CB  . ARG   A 1 135 ? 125.855 151.950 122.392 1.00 49.23  ? 135 ARG   B CB  1 
ATOM   846  N N   . THR   A 1 136 ? 128.833 150.319 123.078 1.00 50.84  ? 136 THR   B N   1 
ATOM   847  C CA  . THR   A 1 136 ? 129.579 149.520 124.038 1.00 50.84  ? 136 THR   B CA  1 
ATOM   848  C C   . THR   A 1 136 ? 131.023 149.361 123.595 1.00 50.84  ? 136 THR   B C   1 
ATOM   849  O O   . THR   A 1 136 ? 131.599 148.274 123.675 1.00 50.84  ? 136 THR   B O   1 
ATOM   850  C CB  . THR   A 1 136 ? 128.932 148.152 124.239 1.00 50.84  ? 136 THR   B CB  1 
ATOM   851  O OG1 . THR   A 1 136 ? 128.771 147.506 122.970 1.00 50.84  ? 136 THR   B OG1 1 
ATOM   852  C CG2 . THR   A 1 136 ? 127.575 148.286 124.918 1.00 50.84  ? 136 THR   B CG2 1 
ATOM   853  N N   . ILE   A 1 137 ? 131.637 150.439 123.121 1.00 44.67  ? 137 ILE   B N   1 
ATOM   854  C CA  . ILE   A 1 137 ? 133.028 150.420 122.693 1.00 44.67  ? 137 ILE   B CA  1 
ATOM   855  C C   . ILE   A 1 137 ? 133.731 151.597 123.337 1.00 44.67  ? 137 ILE   B C   1 
ATOM   856  O O   . ILE   A 1 137 ? 133.332 152.747 123.132 1.00 44.67  ? 137 ILE   B O   1 
ATOM   857  C CB  . ILE   A 1 137 ? 133.166 150.480 121.168 1.00 44.67  ? 137 ILE   B CB  1 
ATOM   858  C CG1 . ILE   A 1 137 ? 132.855 149.122 120.559 1.00 44.67  ? 137 ILE   B CG1 1 
ATOM   859  C CG2 . ILE   A 1 137 ? 134.563 150.885 120.784 1.00 44.67  ? 137 ILE   B CG2 1 
ATOM   860  C CD1 . ILE   A 1 137 ? 132.846 149.133 119.063 1.00 44.67  ? 137 ILE   B CD1 1 
ATOM   861  N N   . SER   A 1 138 ? 134.765 151.318 124.120 1.00 40.52  ? 138 SER   B N   1 
ATOM   862  C CA  . SER   A 1 138 ? 135.476 152.365 124.829 1.00 40.52  ? 138 SER   B CA  1 
ATOM   863  C C   . SER   A 1 138 ? 136.408 153.105 123.881 1.00 40.52  ? 138 SER   B C   1 
ATOM   864  O O   . SER   A 1 138 ? 136.694 152.649 122.774 1.00 40.52  ? 138 SER   B O   1 
ATOM   865  C CB  . SER   A 1 138 ? 136.256 151.781 125.997 1.00 40.52  ? 138 SER   B CB  1 
ATOM   866  O OG  . SER   A 1 138 ? 135.378 151.338 127.012 1.00 40.52  ? 138 SER   B OG  1 
ATOM   867  N N   . VAL   A 1 139 ? 136.880 154.263 124.319 1.00 36.67  ? 139 VAL   B N   1 
ATOM   868  C CA  . VAL   A 1 139 ? 137.693 155.135 123.486 1.00 36.67  ? 139 VAL   B CA  1 
ATOM   869  C C   . VAL   A 1 139 ? 138.899 155.600 124.287 1.00 36.67  ? 139 VAL   B C   1 
ATOM   870  O O   . VAL   A 1 139 ? 138.754 156.397 125.220 1.00 36.67  ? 139 VAL   B O   1 
ATOM   871  C CB  . VAL   A 1 139 ? 136.899 156.339 122.973 1.00 36.67  ? 139 VAL   B CB  1 
ATOM   872  C CG1 . VAL   A 1 139 ? 137.817 157.323 122.292 1.00 36.67  ? 139 VAL   B CG1 1 
ATOM   873  C CG2 . VAL   A 1 139 ? 135.815 155.890 122.022 1.00 36.67  ? 139 VAL   B CG2 1 
ATOM   874  N N   . ILE   A 1 140 ? 140.084 155.101 123.942 1.00 36.03  ? 140 ILE   B N   1 
ATOM   875  C CA  . ILE   A 1 140 ? 141.310 155.761 124.368 1.00 36.03  ? 140 ILE   B CA  1 
ATOM   876  C C   . ILE   A 1 140 ? 141.437 157.068 123.610 1.00 36.03  ? 140 ILE   B C   1 
ATOM   877  O O   . ILE   A 1 140 ? 141.289 157.105 122.383 1.00 36.03  ? 140 ILE   B O   1 
ATOM   878  C CB  . ILE   A 1 140 ? 142.540 154.879 124.126 1.00 36.03  ? 140 ILE   B CB  1 
ATOM   879  C CG1 . ILE   A 1 140 ? 142.492 153.620 124.960 1.00 36.03  ? 140 ILE   B CG1 1 
ATOM   880  C CG2 . ILE   A 1 140 ? 143.794 155.630 124.477 1.00 36.03  ? 140 ILE   B CG2 1 
ATOM   881  C CD1 . ILE   A 1 140 ? 141.890 152.496 124.257 1.00 36.03  ? 140 ILE   B CD1 1 
ATOM   882  N N   . LEU   A 1 141 ? 141.704 158.146 124.324 1.00 38.22  ? 141 LEU   B N   1 
ATOM   883  C CA  . LEU   A 1 141 ? 141.844 159.454 123.707 1.00 38.22  ? 141 LEU   B CA  1 
ATOM   884  C C   . LEU   A 1 141 ? 143.274 159.936 123.873 1.00 38.22  ? 141 LEU   B C   1 
ATOM   885  O O   . LEU   A 1 141 ? 143.754 160.098 124.997 1.00 38.22  ? 141 LEU   B O   1 
ATOM   886  C CB  . LEU   A 1 141 ? 140.858 160.448 124.307 1.00 38.22  ? 141 LEU   B CB  1 
ATOM   887  C CG  . LEU   A 1 141 ? 140.778 161.810 123.642 1.00 38.22  ? 141 LEU   B CG  1 
ATOM   888  C CD1 . LEU   A 1 141 ? 140.184 161.705 122.268 1.00 38.22  ? 141 LEU   B CD1 1 
ATOM   889  C CD2 . LEU   A 1 141 ? 139.948 162.723 124.498 1.00 38.22  ? 141 LEU   B CD2 1 
ATOM   890  N N   . PHE   A 1 142 ? 143.942 160.160 122.752 1.00 41.87  ? 142 PHE   B N   1 
ATOM   891  C CA  . PHE   A 1 142 ? 145.289 160.700 122.706 1.00 41.87  ? 142 PHE   B CA  1 
ATOM   892  C C   . PHE   A 1 142 ? 145.218 162.165 122.320 1.00 41.87  ? 142 PHE   B C   1 
ATOM   893  O O   . PHE   A 1 142 ? 144.517 162.524 121.370 1.00 41.87  ? 142 PHE   B O   1 
ATOM   894  C CB  . PHE   A 1 142 ? 146.142 159.956 121.687 1.00 41.87  ? 142 PHE   B CB  1 
ATOM   895  C CG  . PHE   A 1 142 ? 146.838 158.763 122.230 1.00 41.87  ? 142 PHE   B CG  1 
ATOM   896  C CD1 . PHE   A 1 142 ? 146.137 157.663 122.642 1.00 41.87  ? 142 PHE   B CD1 1 
ATOM   897  C CD2 . PHE   A 1 142 ? 148.202 158.728 122.293 1.00 41.87  ? 142 PHE   B CD2 1 
ATOM   898  C CE1 . PHE   A 1 142 ? 146.783 156.572 123.130 1.00 41.87  ? 142 PHE   B CE1 1 
ATOM   899  C CE2 . PHE   A 1 142 ? 148.843 157.628 122.783 1.00 41.87  ? 142 PHE   B CE2 1 
ATOM   900  C CZ  . PHE   A 1 142 ? 148.126 156.553 123.200 1.00 41.87  ? 142 PHE   B CZ  1 
ATOM   901  N N   . LEU   A 1 143 ? 145.952 163.005 123.035 1.00 46.79  ? 143 LEU   B N   1 
ATOM   902  C CA  . LEU   A 1 143 ? 146.042 164.424 122.717 1.00 46.79  ? 143 LEU   B CA  1 
ATOM   903  C C   . LEU   A 1 143 ? 147.488 164.702 122.320 1.00 46.79  ? 143 LEU   B C   1 
ATOM   904  O O   . LEU   A 1 143 ? 148.322 165.041 123.159 1.00 46.79  ? 143 LEU   B O   1 
ATOM   905  C CB  . LEU   A 1 143 ? 145.574 165.276 123.888 1.00 46.79  ? 143 LEU   B CB  1 
ATOM   906  C CG  . LEU   A 1 143 ? 144.054 165.319 124.056 1.00 46.79  ? 143 LEU   B CG  1 
ATOM   907  C CD1 . LEU   A 1 143 ? 143.663 165.387 125.490 1.00 46.79  ? 143 LEU   B CD1 1 
ATOM   908  C CD2 . LEU   A 1 143 ? 143.466 166.482 123.294 1.00 46.79  ? 143 LEU   B CD2 1 
ATOM   909  N N   . ASN   A 1 144 ? 147.780 164.560 121.029 1.00 55.43  ? 144 ASN   B N   1 
ATOM   910  C CA  . ASN   A 1 144 ? 149.144 164.673 120.540 1.00 55.43  ? 144 ASN   B CA  1 
ATOM   911  C C   . ASN   A 1 144 ? 149.672 166.092 120.643 1.00 55.43  ? 144 ASN   B C   1 
ATOM   912  O O   . ASN   A 1 144 ? 148.959 167.041 120.970 1.00 55.43  ? 144 ASN   B O   1 
ATOM   913  C CB  . ASN   A 1 144 ? 149.262 164.240 119.087 1.00 55.43  ? 144 ASN   B CB  1 
ATOM   914  C CG  . ASN   A 1 144 ? 149.555 162.790 118.941 1.00 55.43  ? 144 ASN   B CG  1 
ATOM   915  O OD1 . ASN   A 1 144 ? 150.266 162.208 119.753 1.00 55.43  ? 144 ASN   B OD1 1 
ATOM   916  N ND2 . ASN   A 1 144 ? 149.060 162.197 117.872 1.00 55.43  ? 144 ASN   B ND2 1 
ATOM   917  N N   . LYS   A 1 145 ? 150.959 166.205 120.342 1.00 63.47  ? 145 LYS   B N   1 
ATOM   918  C CA  . LYS   A 1 145 ? 151.671 167.467 120.225 1.00 63.47  ? 145 LYS   B CA  1 
ATOM   919  C C   . LYS   A 1 145 ? 151.455 168.343 121.454 1.00 63.47  ? 145 LYS   B C   1 
ATOM   920  O O   . LYS   A 1 145 ? 150.847 169.412 121.398 1.00 63.47  ? 145 LYS   B O   1 
ATOM   921  C CB  . LYS   A 1 145 ? 151.268 168.184 118.937 1.00 63.47  ? 145 LYS   B CB  1 
ATOM   922  C CG  . LYS   A 1 145 ? 151.674 167.416 117.689 1.00 63.47  ? 145 LYS   B CG  1 
ATOM   923  C CD  . LYS   A 1 145 ? 151.249 168.125 116.421 1.00 63.47  ? 145 LYS   B CD  1 
ATOM   924  C CE  . LYS   A 1 145 ? 151.334 167.199 115.224 1.00 63.47  ? 145 LYS   B CE  1 
ATOM   925  N NZ  . LYS   A 1 145 ? 151.257 167.946 113.938 1.00 63.47  ? 145 LYS   B NZ  1 
ATOM   926  N N   . GLN   A 1 146 ? 151.964 167.863 122.584 1.00 68.44  ? 146 GLN   B N   1 
ATOM   927  C CA  . GLN   A 1 146 ? 151.947 168.678 123.787 1.00 68.44  ? 146 GLN   B CA  1 
ATOM   928  C C   . GLN   A 1 146 ? 153.137 169.628 123.843 1.00 68.44  ? 146 GLN   B C   1 
ATOM   929  O O   . GLN   A 1 146 ? 153.053 170.680 124.490 1.00 68.44  ? 146 GLN   B O   1 
ATOM   930  C CB  . GLN   A 1 146 ? 151.904 167.789 125.028 1.00 68.44  ? 146 GLN   B CB  1 
ATOM   931  C CG  . GLN   A 1 146 ? 153.249 167.286 125.498 1.00 68.44  ? 146 GLN   B CG  1 
ATOM   932  C CD  . GLN   A 1 146 ? 153.211 166.824 126.935 1.00 68.44  ? 146 GLN   B CD  1 
ATOM   933  O OE1 . GLN   A 1 146 ? 152.240 167.067 127.648 1.00 68.44  ? 146 GLN   B OE1 1 
ATOM   934  N NE2 . GLN   A 1 146 ? 154.269 166.150 127.371 1.00 68.44  ? 146 GLN   B NE2 1 
ATOM   935  N N   . ASP   A 1 147 ? 154.240 169.291 123.169 1.00 71.80  ? 147 ASP   B N   1 
ATOM   936  C CA  . ASP   A 1 147 ? 155.374 170.208 123.117 1.00 71.80  ? 147 ASP   B CA  1 
ATOM   937  C C   . ASP   A 1 147 ? 155.015 171.484 122.371 1.00 71.80  ? 147 ASP   B C   1 
ATOM   938  O O   . ASP   A 1 147 ? 155.370 172.588 122.802 1.00 71.80  ? 147 ASP   B O   1 
ATOM   939  C CB  . ASP   A 1 147 ? 156.579 169.528 122.469 1.00 71.80  ? 147 ASP   B CB  1 
ATOM   940  C CG  . ASP   A 1 147 ? 156.209 168.733 121.239 1.00 71.80  ? 147 ASP   B CG  1 
ATOM   941  O OD1 . ASP   A 1 147 ? 155.058 168.854 120.772 1.00 71.80  ? 147 ASP   B OD1 1 
ATOM   942  O OD2 . ASP   A 1 147 ? 157.074 167.988 120.732 1.00 71.80  ? 147 ASP   B OD2 1 
ATOM   943  N N   . LEU   A 1 148 ? 154.308 171.355 121.249 1.00 71.08  ? 148 LEU   B N   1 
ATOM   944  C CA  . LEU   A 1 148 ? 153.856 172.537 120.531 1.00 71.08  ? 148 LEU   B CA  1 
ATOM   945  C C   . LEU   A 1 148 ? 152.857 173.333 121.352 1.00 71.08  ? 148 LEU   B C   1 
ATOM   946  O O   . LEU   A 1 148 ? 152.814 174.563 121.250 1.00 71.08  ? 148 LEU   B O   1 
ATOM   947  C CB  . LEU   A 1 148 ? 153.256 172.137 119.187 1.00 71.08  ? 148 LEU   B CB  1 
ATOM   948  C CG  . LEU   A 1 148 ? 154.256 171.450 118.261 1.00 71.08  ? 148 LEU   B CG  1 
ATOM   949  C CD1 . LEU   A 1 148 ? 153.557 170.765 117.109 1.00 71.08  ? 148 LEU   B CD1 1 
ATOM   950  C CD2 . LEU   A 1 148 ? 155.271 172.449 117.745 1.00 71.08  ? 148 LEU   B CD2 1 
ATOM   951  N N   . LEU   A 1 149 ? 152.045 172.656 122.163 1.00 70.13  ? 149 LEU   B N   1 
ATOM   952  C CA  . LEU   A 1 149 ? 151.142 173.360 123.062 1.00 70.13  ? 149 LEU   B CA  1 
ATOM   953  C C   . LEU   A 1 149 ? 151.920 174.192 124.063 1.00 70.13  ? 149 LEU   B C   1 
ATOM   954  O O   . LEU   A 1 149 ? 151.602 175.363 124.297 1.00 70.13  ? 149 LEU   B O   1 
ATOM   955  C CB  . LEU   A 1 149 ? 150.243 172.364 123.785 1.00 70.13  ? 149 LEU   B CB  1 
ATOM   956  C CG  . LEU   A 1 149 ? 148.959 172.950 124.344 1.00 70.13  ? 149 LEU   B CG  1 
ATOM   957  C CD1 . LEU   A 1 149 ? 148.103 173.470 123.217 1.00 70.13  ? 149 LEU   B CD1 1 
ATOM   958  C CD2 . LEU   A 1 149 ? 148.209 171.903 125.144 1.00 70.13  ? 149 LEU   B CD2 1 
ATOM   959  N N   . ALA   A 1 150 ? 152.960 173.604 124.655 1.00 76.03  ? 150 ALA   B N   1 
ATOM   960  C CA  . ALA   A 1 150 ? 153.794 174.356 125.583 1.00 76.03  ? 150 ALA   B CA  1 
ATOM   961  C C   . ALA   A 1 150 ? 154.445 175.543 124.888 1.00 76.03  ? 150 ALA   B C   1 
ATOM   962  O O   . ALA   A 1 150 ? 154.521 176.639 125.454 1.00 76.03  ? 150 ALA   B O   1 
ATOM   963  C CB  . ALA   A 1 150 ? 154.853 173.443 126.200 1.00 76.03  ? 150 ALA   B CB  1 
ATOM   964  N N   . GLU   A 1 151 ? 154.913 175.345 123.656 1.00 75.91  ? 151 GLU   B N   1 
ATOM   965  C CA  . GLU   A 1 151 ? 155.568 176.430 122.936 1.00 75.91  ? 151 GLU   B CA  1 
ATOM   966  C C   . GLU   A 1 151 ? 154.596 177.566 122.651 1.00 75.91  ? 151 GLU   B C   1 
ATOM   967  O O   . GLU   A 1 151 ? 154.898 178.735 122.916 1.00 75.91  ? 151 GLU   B O   1 
ATOM   968  C CB  . GLU   A 1 151 ? 156.180 175.905 121.642 1.00 75.91  ? 151 GLU   B CB  1 
ATOM   969  C CG  . GLU   A 1 151 ? 157.418 175.061 121.853 1.00 75.91  ? 151 GLU   B CG  1 
ATOM   970  C CD  . GLU   A 1 151 ? 157.844 174.331 120.598 1.00 75.91  ? 151 GLU   B CD  1 
ATOM   971  O OE1 . GLU   A 1 151 ? 157.255 174.591 119.528 1.00 75.91  ? 151 GLU   B OE1 1 
ATOM   972  O OE2 . GLU   A 1 151 ? 158.768 173.495 120.680 1.00 75.91  ? 151 GLU   B OE2 1 
ATOM   973  N N   . LYS   A 1 152 ? 153.416 177.244 122.118 1.00 75.81  ? 152 LYS   B N   1 
ATOM   974  C CA  . LYS   A 1 152 ? 152.448 178.282 121.779 1.00 75.81  ? 152 LYS   B CA  1 
ATOM   975  C C   . LYS   A 1 152 ? 151.798 178.892 123.012 1.00 75.81  ? 152 LYS   B C   1 
ATOM   976  O O   . LYS   A 1 152 ? 151.183 179.957 122.904 1.00 75.81  ? 152 LYS   B O   1 
ATOM   977  C CB  . LYS   A 1 152 ? 151.367 177.728 120.846 1.00 75.81  ? 152 LYS   B CB  1 
ATOM   978  N N   . VAL   A 1 153 ? 151.910 178.250 124.171 1.00 75.24  ? 153 VAL   B N   1 
ATOM   979  C CA  . VAL   A 1 153 ? 151.357 178.827 125.388 1.00 75.24  ? 153 VAL   B CA  1 
ATOM   980  C C   . VAL   A 1 153 ? 152.369 179.725 126.087 1.00 75.24  ? 153 VAL   B C   1 
ATOM   981  O O   . VAL   A 1 153 ? 152.029 180.825 126.528 1.00 75.24  ? 153 VAL   B O   1 
ATOM   982  C CB  . VAL   A 1 153 ? 150.854 177.706 126.312 1.00 75.24  ? 153 VAL   B CB  1 
ATOM   983  C CG1 . VAL   A 1 153 ? 150.763 178.194 127.750 1.00 75.24  ? 153 VAL   B CG1 1 
ATOM   984  C CG2 . VAL   A 1 153 ? 149.500 177.214 125.838 1.00 75.24  ? 153 VAL   B CG2 1 
ATOM   985  N N   . LEU   A 1 154 ? 153.623 179.280 126.192 1.00 79.35  ? 154 LEU   B N   1 
ATOM   986  C CA  . LEU   A 1 154 ? 154.666 180.119 126.767 1.00 79.35  ? 154 LEU   B CA  1 
ATOM   987  C C   . LEU   A 1 154 ? 154.970 181.316 125.874 1.00 79.35  ? 154 LEU   B C   1 
ATOM   988  O O   . LEU   A 1 154 ? 155.244 182.414 126.373 1.00 79.35  ? 154 LEU   B O   1 
ATOM   989  C CB  . LEU   A 1 154 ? 155.927 179.291 126.998 1.00 79.35  ? 154 LEU   B CB  1 
ATOM   990  C CG  . LEU   A 1 154 ? 155.846 178.225 128.089 1.00 79.35  ? 154 LEU   B CG  1 
ATOM   991  C CD1 . LEU   A 1 154 ? 157.223 177.647 128.374 1.00 79.35  ? 154 LEU   B CD1 1 
ATOM   992  C CD2 . LEU   A 1 154 ? 155.229 178.798 129.355 1.00 79.35  ? 154 LEU   B CD2 1 
ATOM   993  N N   . ALA   A 1 155 ? 154.937 181.122 124.551 1.00 80.10  ? 155 ALA   B N   1 
ATOM   994  C CA  . ALA   A 1 155 ? 155.264 182.205 123.629 1.00 80.10  ? 155 ALA   B CA  1 
ATOM   995  C C   . ALA   A 1 155 ? 154.271 183.353 123.743 1.00 80.10  ? 155 ALA   B C   1 
ATOM   996  O O   . ALA   A 1 155 ? 154.665 184.525 123.758 1.00 80.10  ? 155 ALA   B O   1 
ATOM   997  C CB  . ALA   A 1 155 ? 155.311 181.675 122.198 1.00 80.10  ? 155 ALA   B CB  1 
ATOM   998  N N   . GLY   A 1 156 ? 152.982 183.042 123.824 1.00 83.98  ? 156 GLY   B N   1 
ATOM   999  C CA  . GLY   A 1 156 ? 151.979 184.064 124.024 1.00 83.98  ? 156 GLY   B CA  1 
ATOM   1000 C C   . GLY   A 1 156 ? 151.534 184.796 122.780 1.00 83.98  ? 156 GLY   B C   1 
ATOM   1001 O O   . GLY   A 1 156 ? 150.790 185.776 122.896 1.00 83.98  ? 156 GLY   B O   1 
ATOM   1002 N N   . LYS   A 1 157 ? 151.968 184.360 121.595 1.00 87.34  ? 157 LYS   B N   1 
ATOM   1003 C CA  . LYS   A 1 157 ? 151.550 185.026 120.365 1.00 87.34  ? 157 LYS   B CA  1 
ATOM   1004 C C   . LYS   A 1 157 ? 150.048 184.893 120.149 1.00 87.34  ? 157 LYS   B C   1 
ATOM   1005 O O   . LYS   A 1 157 ? 149.385 185.851 119.734 1.00 87.34  ? 157 LYS   B O   1 
ATOM   1006 C CB  . LYS   A 1 157 ? 152.317 184.457 119.172 1.00 87.34  ? 157 LYS   B CB  1 
ATOM   1007 N N   . SER   A 1 158 ? 149.495 183.716 120.423 1.00 84.87  ? 158 SER   B N   1 
ATOM   1008 C CA  . SER   A 1 158 ? 148.069 183.463 120.295 1.00 84.87  ? 158 SER   B CA  1 
ATOM   1009 C C   . SER   A 1 158 ? 147.483 183.150 121.663 1.00 84.87  ? 158 SER   B C   1 
ATOM   1010 O O   . SER   A 1 158 ? 148.206 182.889 122.627 1.00 84.87  ? 158 SER   B O   1 
ATOM   1011 C CB  . SER   A 1 158 ? 147.791 182.308 119.325 1.00 84.87  ? 158 SER   B CB  1 
ATOM   1012 O OG  . SER   A 1 158 ? 148.413 182.532 118.072 1.00 84.87  ? 158 SER   B OG  1 
ATOM   1013 N N   . LYS   A 1 159 ? 146.156 183.180 121.742 1.00 79.55  ? 159 LYS   B N   1 
ATOM   1014 C CA  . LYS   A 1 159 ? 145.450 182.933 122.991 1.00 79.55  ? 159 LYS   B CA  1 
ATOM   1015 C C   . LYS   A 1 159 ? 144.337 181.930 122.754 1.00 79.55  ? 159 LYS   B C   1 
ATOM   1016 O O   . LYS   A 1 159 ? 143.549 182.083 121.815 1.00 79.55  ? 159 LYS   B O   1 
ATOM   1017 C CB  . LYS   A 1 159 ? 144.875 184.230 123.569 1.00 79.55  ? 159 LYS   B CB  1 
ATOM   1018 N N   . ILE   A 1 160 ? 144.274 180.906 123.606 1.00 74.26  ? 160 ILE   B N   1 
ATOM   1019 C CA  . ILE   A 1 160 ? 143.175 179.949 123.533 1.00 74.26  ? 160 ILE   B CA  1 
ATOM   1020 C C   . ILE   A 1 160 ? 141.860 180.637 123.861 1.00 74.26  ? 160 ILE   B C   1 
ATOM   1021 O O   . ILE   A 1 160 ? 140.813 180.320 123.281 1.00 74.26  ? 160 ILE   B O   1 
ATOM   1022 C CB  . ILE   A 1 160 ? 143.435 178.748 124.462 1.00 74.26  ? 160 ILE   B CB  1 
ATOM   1023 C CG1 . ILE   A 1 160 ? 144.670 177.965 124.019 1.00 74.26  ? 160 ILE   B CG1 1 
ATOM   1024 C CG2 . ILE   A 1 160 ? 142.229 177.831 124.509 1.00 74.26  ? 160 ILE   B CG2 1 
ATOM   1025 C CD1 . ILE   A 1 160 ? 145.969 178.440 124.633 1.00 74.26  ? 160 ILE   B CD1 1 
ATOM   1026 N N   . GLU   A 1 161 ? 141.892 181.599 124.784 1.00 74.56  ? 161 GLU   B N   1 
ATOM   1027 C CA  . GLU   A 1 161 ? 140.678 182.310 125.167 1.00 74.56  ? 161 GLU   B CA  1 
ATOM   1028 C C   . GLU   A 1 161 ? 140.062 183.077 124.006 1.00 74.56  ? 161 GLU   B C   1 
ATOM   1029 O O   . GLU   A 1 161 ? 138.881 183.431 124.074 1.00 74.56  ? 161 GLU   B O   1 
ATOM   1030 C CB  . GLU   A 1 161 ? 140.973 183.267 126.323 1.00 74.56  ? 161 GLU   B CB  1 
ATOM   1031 N N   . ASP   A 1 162 ? 140.836 183.355 122.954 1.00 75.59  ? 162 ASP   B N   1 
ATOM   1032 C CA  . ASP   A 1 162 ? 140.284 184.027 121.781 1.00 75.59  ? 162 ASP   B CA  1 
ATOM   1033 C C   . ASP   A 1 162 ? 139.326 183.116 121.024 1.00 75.59  ? 162 ASP   B C   1 
ATOM   1034 O O   . ASP   A 1 162 ? 138.206 183.517 120.690 1.00 75.59  ? 162 ASP   B O   1 
ATOM   1035 C CB  . ASP   A 1 162 ? 141.412 184.497 120.864 1.00 75.59  ? 162 ASP   B CB  1 
ATOM   1036 N N   . TYR   A 1 163 ? 139.750 181.886 120.737 1.00 73.98  ? 163 TYR   B N   1 
ATOM   1037 C CA  . TYR   A 1 163 ? 138.846 180.938 120.098 1.00 73.98  ? 163 TYR   B CA  1 
ATOM   1038 C C   . TYR   A 1 163 ? 137.821 180.393 121.083 1.00 73.98  ? 163 TYR   B C   1 
ATOM   1039 O O   . TYR   A 1 163 ? 136.637 180.273 120.752 1.00 73.98  ? 163 TYR   B O   1 
ATOM   1040 C CB  . TYR   A 1 163 ? 139.634 179.797 119.464 1.00 73.98  ? 163 TYR   B CB  1 
ATOM   1041 C CG  . TYR   A 1 163 ? 140.692 180.260 118.508 1.00 73.98  ? 163 TYR   B CG  1 
ATOM   1042 C CD1 . TYR   A 1 163 ? 142.004 180.400 118.915 1.00 73.98  ? 163 TYR   B CD1 1 
ATOM   1043 C CD2 . TYR   A 1 163 ? 140.379 180.560 117.198 1.00 73.98  ? 163 TYR   B CD2 1 
ATOM   1044 C CE1 . TYR   A 1 163 ? 142.975 180.821 118.045 1.00 73.98  ? 163 TYR   B CE1 1 
ATOM   1045 C CE2 . TYR   A 1 163 ? 141.345 180.985 116.319 1.00 73.98  ? 163 TYR   B CE2 1 
ATOM   1046 C CZ  . TYR   A 1 163 ? 142.642 181.114 116.749 1.00 73.98  ? 163 TYR   B CZ  1 
ATOM   1047 O OH  . TYR   A 1 163 ? 143.615 181.538 115.874 1.00 73.98  ? 163 TYR   B OH  1 
ATOM   1048 N N   . PHE   A 1 164 ? 138.252 180.056 122.295 1.00 70.60  ? 164 PHE   B N   1 
ATOM   1049 C CA  . PHE   A 1 164 ? 137.371 179.403 123.248 1.00 70.60  ? 164 PHE   B CA  1 
ATOM   1050 C C   . PHE   A 1 164 ? 136.863 180.421 124.248 1.00 70.60  ? 164 PHE   B C   1 
ATOM   1051 O O   . PHE   A 1 164 ? 137.665 180.973 125.018 1.00 70.60  ? 164 PHE   B O   1 
ATOM   1052 C CB  . PHE   A 1 164 ? 138.091 178.268 123.967 1.00 70.60  ? 164 PHE   B CB  1 
ATOM   1053 C CG  . PHE   A 1 164 ? 138.160 177.001 123.169 1.00 70.60  ? 164 PHE   B CG  1 
ATOM   1054 C CD1 . PHE   A 1 164 ? 137.123 176.640 122.338 1.00 70.60  ? 164 PHE   B CD1 1 
ATOM   1055 C CD2 . PHE   A 1 164 ? 139.260 176.182 123.241 1.00 70.60  ? 164 PHE   B CD2 1 
ATOM   1056 C CE1 . PHE   A 1 164 ? 137.182 175.489 121.601 1.00 70.60  ? 164 PHE   B CE1 1 
ATOM   1057 C CE2 . PHE   A 1 164 ? 139.322 175.028 122.505 1.00 70.60  ? 164 PHE   B CE2 1 
ATOM   1058 C CZ  . PHE   A 1 164 ? 138.279 174.682 121.685 1.00 70.60  ? 164 PHE   B CZ  1 
ATOM   1059 N N   . PRO   A 1 165 ? 135.564 180.711 124.270 1.00 73.03  ? 165 PRO   B N   1 
ATOM   1060 C CA  . PRO   A 1 165 ? 135.058 181.726 125.205 1.00 73.03  ? 165 PRO   B CA  1 
ATOM   1061 C C   . PRO   A 1 165 ? 135.252 181.371 126.666 1.00 73.03  ? 165 PRO   B C   1 
ATOM   1062 O O   . PRO   A 1 165 ? 135.451 182.274 127.487 1.00 73.03  ? 165 PRO   B O   1 
ATOM   1063 C CB  . PRO   A 1 165 ? 133.567 181.822 124.846 1.00 73.03  ? 165 PRO   B CB  1 
ATOM   1064 C CG  . PRO   A 1 165 ? 133.445 181.207 123.483 1.00 73.03  ? 165 PRO   B CG  1 
ATOM   1065 C CD  . PRO   A 1 165 ? 134.497 180.150 123.427 1.00 73.03  ? 165 PRO   B CD  1 
ATOM   1066 N N   . GLU   A 1 166 ? 135.207 180.089 127.021 1.00 68.07  ? 166 GLU   B N   1 
ATOM   1067 C CA  . GLU   A 1 166 ? 135.053 179.673 128.413 1.00 68.07  ? 166 GLU   B CA  1 
ATOM   1068 C C   . GLU   A 1 166 ? 136.364 179.252 129.064 1.00 68.07  ? 166 GLU   B C   1 
ATOM   1069 O O   . GLU   A 1 166 ? 136.378 178.312 129.861 1.00 68.07  ? 166 GLU   B O   1 
ATOM   1070 C CB  . GLU   A 1 166 ? 134.024 178.552 128.509 1.00 68.07  ? 166 GLU   B CB  1 
ATOM   1071 N N   . PHE   A 1 167 ? 137.481 179.910 128.764 1.00 66.27  ? 167 PHE   B N   1 
ATOM   1072 C CA  . PHE   A 1 167 ? 138.725 179.599 129.451 1.00 66.27  ? 167 PHE   B CA  1 
ATOM   1073 C C   . PHE   A 1 167 ? 139.072 180.592 130.553 1.00 66.27  ? 167 PHE   B C   1 
ATOM   1074 O O   . PHE   A 1 167 ? 140.007 180.339 131.319 1.00 66.27  ? 167 PHE   B O   1 
ATOM   1075 C CB  . PHE   A 1 167 ? 139.882 179.520 128.457 1.00 66.27  ? 167 PHE   B CB  1 
ATOM   1076 C CG  . PHE   A 1 167 ? 141.110 178.882 129.019 1.00 66.27  ? 167 PHE   B CG  1 
ATOM   1077 C CD1 . PHE   A 1 167 ? 141.006 177.837 129.906 1.00 66.27  ? 167 PHE   B CD1 1 
ATOM   1078 C CD2 . PHE   A 1 167 ? 142.359 179.295 128.632 1.00 66.27  ? 167 PHE   B CD2 1 
ATOM   1079 C CE1 . PHE   A 1 167 ? 142.129 177.242 130.422 1.00 66.27  ? 167 PHE   B CE1 1 
ATOM   1080 C CE2 . PHE   A 1 167 ? 143.478 178.700 129.138 1.00 66.27  ? 167 PHE   B CE2 1 
ATOM   1081 C CZ  . PHE   A 1 167 ? 143.367 177.673 130.029 1.00 66.27  ? 167 PHE   B CZ  1 
ATOM   1082 N N   . ALA   A 1 168 ? 138.347 181.706 130.661 1.00 71.38  ? 168 ALA   B N   1 
ATOM   1083 C CA  . ALA   A 1 168 ? 138.632 182.658 131.728 1.00 71.38  ? 168 ALA   B CA  1 
ATOM   1084 C C   . ALA   A 1 168 ? 138.256 182.094 133.093 1.00 71.38  ? 168 ALA   B C   1 
ATOM   1085 O O   . ALA   A 1 168 ? 139.046 182.165 134.038 1.00 71.38  ? 168 ALA   B O   1 
ATOM   1086 C CB  . ALA   A 1 168 ? 137.899 183.973 131.467 1.00 71.38  ? 168 ALA   B CB  1 
ATOM   1087 N N   . ARG   A 1 169 ? 137.060 181.513 133.209 1.00 75.24  ? 169 ARG   B N   1 
ATOM   1088 C CA  . ARG   A 1 169 ? 136.591 181.026 134.501 1.00 75.24  ? 169 ARG   B CA  1 
ATOM   1089 C C   . ARG   A 1 169 ? 137.416 179.853 135.009 1.00 75.24  ? 169 ARG   B C   1 
ATOM   1090 O O   . ARG   A 1 169 ? 137.621 179.724 136.222 1.00 75.24  ? 169 ARG   B O   1 
ATOM   1091 C CB  . ARG   A 1 169 ? 135.121 180.624 134.410 1.00 75.24  ? 169 ARG   B CB  1 
ATOM   1092 N N   . TYR   A 1 170 ? 137.887 178.991 134.114 1.00 74.23  ? 170 TYR   B N   1 
ATOM   1093 C CA  . TYR   A 1 170 ? 138.541 177.760 134.534 1.00 74.23  ? 170 TYR   B CA  1 
ATOM   1094 C C   . TYR   A 1 170 ? 139.856 178.047 135.245 1.00 74.23  ? 170 TYR   B C   1 
ATOM   1095 O O   . TYR   A 1 170 ? 140.614 178.938 134.854 1.00 74.23  ? 170 TYR   B O   1 
ATOM   1096 C CB  . TYR   A 1 170 ? 138.786 176.852 133.331 1.00 74.23  ? 170 TYR   B CB  1 
ATOM   1097 C CG  . TYR   A 1 170 ? 139.488 175.567 133.689 1.00 74.23  ? 170 TYR   B CG  1 
ATOM   1098 C CD1 . TYR   A 1 170 ? 138.805 174.533 134.306 1.00 74.23  ? 170 TYR   B CD1 1 
ATOM   1099 C CD2 . TYR   A 1 170 ? 140.835 175.394 133.426 1.00 74.23  ? 170 TYR   B CD2 1 
ATOM   1100 C CE1 . TYR   A 1 170 ? 139.444 173.360 134.642 1.00 74.23  ? 170 TYR   B CE1 1 
ATOM   1101 C CE2 . TYR   A 1 170 ? 141.480 174.226 133.760 1.00 74.23  ? 170 TYR   B CE2 1 
ATOM   1102 C CZ  . TYR   A 1 170 ? 140.779 173.214 134.369 1.00 74.23  ? 170 TYR   B CZ  1 
ATOM   1103 O OH  . TYR   A 1 170 ? 141.416 172.042 134.703 1.00 74.23  ? 170 TYR   B OH  1 
ATOM   1104 N N   . THR   A 1 171 ? 140.118 177.287 136.302 1.00 80.88  ? 171 THR   B N   1 
ATOM   1105 C CA  . THR   A 1 171 ? 141.368 177.355 137.039 1.00 80.88  ? 171 THR   B CA  1 
ATOM   1106 C C   . THR   A 1 171 ? 141.878 175.944 137.280 1.00 80.88  ? 171 THR   B C   1 
ATOM   1107 O O   . THR   A 1 171 ? 141.099 174.988 137.324 1.00 80.88  ? 171 THR   B O   1 
ATOM   1108 C CB  . THR   A 1 171 ? 141.203 178.086 138.377 1.00 80.88  ? 171 THR   B CB  1 
ATOM   1109 O OG1 . THR   A 1 171 ? 142.458 178.108 139.070 1.00 80.88  ? 171 THR   B OG1 1 
ATOM   1110 C CG2 . THR   A 1 171 ? 140.159 177.394 139.240 1.00 80.88  ? 171 THR   B CG2 1 
ATOM   1111 N N   . THR   A 1 172 ? 143.191 175.818 137.419 1.00 85.52  ? 172 THR   B N   1 
ATOM   1112 C CA  . THR   A 1 172 ? 143.789 174.506 137.629 1.00 85.52  ? 172 THR   B CA  1 
ATOM   1113 C C   . THR   A 1 172 ? 143.318 173.940 138.964 1.00 85.52  ? 172 THR   B C   1 
ATOM   1114 O O   . THR   A 1 172 ? 143.413 174.628 139.990 1.00 85.52  ? 172 THR   B O   1 
ATOM   1115 C CB  . THR   A 1 172 ? 145.313 174.595 137.605 1.00 85.52  ? 172 THR   B CB  1 
ATOM   1116 O OG1 . THR   A 1 172 ? 145.729 175.436 136.523 1.00 85.52  ? 172 THR   B OG1 1 
ATOM   1117 C CG2 . THR   A 1 172 ? 145.924 173.216 137.427 1.00 85.52  ? 172 THR   B CG2 1 
ATOM   1118 N N   . PRO   A 1 173 ? 142.808 172.713 138.999 1.00 92.69  ? 173 PRO   B N   1 
ATOM   1119 C CA  . PRO   A 1 173 ? 142.278 172.169 140.253 1.00 92.69  ? 173 PRO   B CA  1 
ATOM   1120 C C   . PRO   A 1 173 ? 143.390 171.892 141.253 1.00 92.69  ? 173 PRO   B C   1 
ATOM   1121 O O   . PRO   A 1 173 ? 144.583 171.988 140.958 1.00 92.69  ? 173 PRO   B O   1 
ATOM   1122 C CB  . PRO   A 1 173 ? 141.582 170.879 139.814 1.00 92.69  ? 173 PRO   B CB  1 
ATOM   1123 C CG  . PRO   A 1 173 ? 142.277 170.491 138.559 1.00 92.69  ? 173 PRO   B CG  1 
ATOM   1124 C CD  . PRO   A 1 173 ? 142.667 171.769 137.881 1.00 92.69  ? 173 PRO   B CD  1 
ATOM   1125 N N   . GLU   A 1 174 ? 142.973 171.536 142.466 1.00 100.01 ? 174 GLU   B N   1 
ATOM   1126 C CA  . GLU   A 1 174 ? 143.892 171.239 143.563 1.00 100.01 ? 174 GLU   B CA  1 
ATOM   1127 C C   . GLU   A 1 174 ? 144.629 169.917 143.388 1.00 100.01 ? 174 GLU   B C   1 
ATOM   1128 O O   . GLU   A 1 174 ? 145.335 169.498 144.314 1.00 100.01 ? 174 GLU   B O   1 
ATOM   1129 C CB  . GLU   A 1 174 ? 143.133 171.238 144.890 1.00 100.01 ? 174 GLU   B CB  1 
ATOM   1130 N N   . ASP   A 1 175 ? 144.484 169.256 142.241 1.00 101.59 ? 175 ASP   B N   1 
ATOM   1131 C CA  . ASP   A 1 175 ? 145.141 167.981 141.989 1.00 101.59 ? 175 ASP   B CA  1 
ATOM   1132 C C   . ASP   A 1 175 ? 145.929 168.029 140.686 1.00 101.59 ? 175 ASP   B C   1 
ATOM   1133 O O   . ASP   A 1 175 ? 145.798 167.136 139.842 1.00 101.59 ? 175 ASP   B O   1 
ATOM   1134 C CB  . ASP   A 1 175 ? 144.115 166.847 141.951 1.00 101.59 ? 175 ASP   B CB  1 
ATOM   1135 N N   . ALA   A 1 176 ? 146.747 169.068 140.512 1.00 100.65 ? 176 ALA   B N   1 
ATOM   1136 C CA  . ALA   A 1 176 ? 147.513 169.264 139.281 1.00 100.65 ? 176 ALA   B CA  1 
ATOM   1137 C C   . ALA   A 1 176 ? 148.637 168.233 139.232 1.00 100.65 ? 176 ALA   B C   1 
ATOM   1138 O O   . ALA   A 1 176 ? 149.811 168.523 139.475 1.00 100.65 ? 176 ALA   B O   1 
ATOM   1139 C CB  . ALA   A 1 176 ? 148.055 170.686 139.205 1.00 100.65 ? 176 ALA   B CB  1 
ATOM   1140 N N   . THR   A 1 177 ? 148.255 167.001 138.889 1.00 100.66 ? 177 THR   B N   1 
ATOM   1141 C CA  . THR   A 1 177 ? 149.123 165.828 138.854 1.00 100.66 ? 177 THR   B CA  1 
ATOM   1142 C C   . THR   A 1 177 ? 150.302 166.028 137.909 1.00 100.66 ? 177 THR   B C   1 
ATOM   1143 O O   . THR   A 1 177 ? 151.315 165.327 138.032 1.00 100.66 ? 177 THR   B O   1 
ATOM   1144 C CB  . THR   A 1 177 ? 148.328 164.588 138.439 1.00 100.66 ? 177 THR   B CB  1 
ATOM   1145 N N   . PRO   A 1 178 ? 150.203 166.946 136.948 1.00 97.95  ? 178 PRO   B N   1 
ATOM   1146 C CA  . PRO   A 1 178 ? 151.315 167.154 136.014 1.00 97.95  ? 178 PRO   B CA  1 
ATOM   1147 C C   . PRO   A 1 178 ? 152.588 167.547 136.747 1.00 97.95  ? 178 PRO   B C   1 
ATOM   1148 O O   . PRO   A 1 178 ? 152.553 168.185 137.801 1.00 97.95  ? 178 PRO   B O   1 
ATOM   1149 C CB  . PRO   A 1 178 ? 150.815 168.287 135.111 1.00 97.95  ? 178 PRO   B CB  1 
ATOM   1150 N N   . GLU   A 1 179 ? 153.722 167.145 136.172 1.00 100.85 ? 179 GLU   B N   1 
ATOM   1151 C CA  . GLU   A 1 179 ? 155.006 167.288 136.836 1.00 100.85 ? 179 GLU   B CA  1 
ATOM   1152 C C   . GLU   A 1 179 ? 155.363 168.760 137.029 1.00 100.85 ? 179 GLU   B C   1 
ATOM   1153 O O   . GLU   A 1 179 ? 154.880 169.631 136.302 1.00 100.85 ? 179 GLU   B O   1 
ATOM   1154 C CB  . GLU   A 1 179 ? 156.101 166.587 136.035 1.00 100.85 ? 179 GLU   B CB  1 
ATOM   1155 N N   . PRO   A 1 180 ? 156.210 169.058 138.017 1.00 101.44 ? 180 PRO   B N   1 
ATOM   1156 C CA  . PRO   A 1 180 ? 156.545 170.464 138.299 1.00 101.44 ? 180 PRO   B CA  1 
ATOM   1157 C C   . PRO   A 1 180 ? 157.299 171.156 137.177 1.00 101.44 ? 180 PRO   B C   1 
ATOM   1158 O O   . PRO   A 1 180 ? 157.360 172.392 137.167 1.00 101.44 ? 180 PRO   B O   1 
ATOM   1159 C CB  . PRO   A 1 180 ? 157.397 170.372 139.572 1.00 101.44 ? 180 PRO   B CB  1 
ATOM   1160 N N   . GLY   A 1 181 ? 157.874 170.412 136.236 1.00 95.92  ? 181 GLY   B N   1 
ATOM   1161 C CA  . GLY   A 1 181 ? 158.647 171.020 135.173 1.00 95.92  ? 181 GLY   B CA  1 
ATOM   1162 C C   . GLY   A 1 181 ? 157.811 171.707 134.112 1.00 95.92  ? 181 GLY   B C   1 
ATOM   1163 O O   . GLY   A 1 181 ? 158.281 171.930 132.993 1.00 95.92  ? 181 GLY   B O   1 
ATOM   1164 N N   . GLU   A 1 182 ? 156.570 172.050 134.448 1.00 89.78  ? 182 GLU   B N   1 
ATOM   1165 C CA  . GLU   A 1 182 ? 155.670 172.714 133.520 1.00 89.78  ? 182 GLU   B CA  1 
ATOM   1166 C C   . GLU   A 1 182 ? 155.113 173.971 134.167 1.00 89.78  ? 182 GLU   B C   1 
ATOM   1167 O O   . GLU   A 1 182 ? 154.745 173.964 135.344 1.00 89.78  ? 182 GLU   B O   1 
ATOM   1168 C CB  . GLU   A 1 182 ? 154.523 171.790 133.097 1.00 89.78  ? 182 GLU   B CB  1 
ATOM   1169 C CG  . GLU   A 1 182 ? 154.949 170.640 132.200 1.00 89.78  ? 182 GLU   B CG  1 
ATOM   1170 C CD  . GLU   A 1 182 ? 153.806 169.697 131.879 1.00 89.78  ? 182 GLU   B CD  1 
ATOM   1171 O OE1 . GLU   A 1 182 ? 152.709 169.876 132.448 1.00 89.78  ? 182 GLU   B OE1 1 
ATOM   1172 O OE2 . GLU   A 1 182 ? 154.004 168.777 131.058 1.00 89.78  ? 182 GLU   B OE2 1 
ATOM   1173 N N   . ASP   A 1 183 ? 155.054 175.047 133.391 1.00 83.00  ? 183 ASP   B N   1 
ATOM   1174 C CA  . ASP   A 1 183 ? 154.529 176.298 133.903 1.00 83.00  ? 183 ASP   B CA  1 
ATOM   1175 C C   . ASP   A 1 183 ? 153.036 176.161 134.194 1.00 83.00  ? 183 ASP   B C   1 
ATOM   1176 O O   . ASP   A 1 183 ? 152.351 175.332 133.589 1.00 83.00  ? 183 ASP   B O   1 
ATOM   1177 C CB  . ASP   A 1 183 ? 154.766 177.426 132.902 1.00 83.00  ? 183 ASP   B CB  1 
ATOM   1178 N N   . PRO   A 1 184 ? 152.514 176.951 135.135 1.00 80.15  ? 184 PRO   B N   1 
ATOM   1179 C CA  . PRO   A 1 184 ? 151.076 176.876 135.435 1.00 80.15  ? 184 PRO   B CA  1 
ATOM   1180 C C   . PRO   A 1 184 ? 150.170 177.089 134.233 1.00 80.15  ? 184 PRO   B C   1 
ATOM   1181 O O   . PRO   A 1 184 ? 149.135 176.420 134.132 1.00 80.15  ? 184 PRO   B O   1 
ATOM   1182 C CB  . PRO   A 1 184 ? 150.898 177.977 136.484 1.00 80.15  ? 184 PRO   B CB  1 
ATOM   1183 C CG  . PRO   A 1 184 ? 152.202 178.003 137.192 1.00 80.15  ? 184 PRO   B CG  1 
ATOM   1184 C CD  . PRO   A 1 184 ? 153.250 177.713 136.156 1.00 80.15  ? 184 PRO   B CD  1 
ATOM   1185 N N   . ARG   A 1 185 ? 150.517 177.994 133.316 1.00 79.22  ? 185 ARG   B N   1 
ATOM   1186 C CA  . ARG   A 1 185 ? 149.660 178.220 132.155 1.00 79.22  ? 185 ARG   B CA  1 
ATOM   1187 C C   . ARG   A 1 185 ? 149.605 176.988 131.261 1.00 79.22  ? 185 ARG   B C   1 
ATOM   1188 O O   . ARG   A 1 185 ? 148.537 176.633 130.743 1.00 79.22  ? 185 ARG   B O   1 
ATOM   1189 C CB  . ARG   A 1 185 ? 150.141 179.436 131.364 1.00 79.22  ? 185 ARG   B CB  1 
ATOM   1190 C CG  . ARG   A 1 185 ? 149.727 180.771 131.969 1.00 79.22  ? 185 ARG   B CG  1 
ATOM   1191 C CD  . ARG   A 1 185 ? 150.162 181.964 131.114 1.00 79.22  ? 185 ARG   B CD  1 
ATOM   1192 N NE  . ARG   A 1 185 ? 151.481 181.800 130.505 1.00 79.22  ? 185 ARG   B NE  1 
ATOM   1193 C CZ  . ARG   A 1 185 ? 152.632 181.856 131.167 1.00 79.22  ? 185 ARG   B CZ  1 
ATOM   1194 N NH1 . ARG   A 1 185 ? 152.644 182.070 132.475 1.00 79.22  ? 185 ARG   B NH1 1 
ATOM   1195 N NH2 . ARG   A 1 185 ? 153.776 181.697 130.517 1.00 79.22  ? 185 ARG   B NH2 1 
ATOM   1196 N N   . VAL   A 1 186 ? 150.746 176.321 131.070 1.00 74.11  ? 186 VAL   B N   1 
ATOM   1197 C CA  . VAL   A 1 186 ? 150.790 175.121 130.240 1.00 74.11  ? 186 VAL   B CA  1 
ATOM   1198 C C   . VAL   A 1 186 ? 149.876 174.046 130.811 1.00 74.11  ? 186 VAL   B C   1 
ATOM   1199 O O   . VAL   A 1 186 ? 149.041 173.472 130.100 1.00 74.11  ? 186 VAL   B O   1 
ATOM   1200 C CB  . VAL   A 1 186 ? 152.238 174.618 130.109 1.00 74.11  ? 186 VAL   B CB  1 
ATOM   1201 C CG1 . VAL   A 1 186 ? 152.291 173.313 129.362 1.00 74.11  ? 186 VAL   B CG1 1 
ATOM   1202 C CG2 . VAL   A 1 186 ? 153.092 175.658 129.409 1.00 74.11  ? 186 VAL   B CG2 1 
ATOM   1203 N N   . THR   A 1 187 ? 150.015 173.767 132.106 1.00 72.01  ? 187 THR   B N   1 
ATOM   1204 C CA  . THR   A 1 187 ? 149.178 172.759 132.742 1.00 72.01  ? 187 THR   B CA  1 
ATOM   1205 C C   . THR   A 1 187 ? 147.711 173.152 132.695 1.00 72.01  ? 187 THR   B C   1 
ATOM   1206 O O   . THR   A 1 187 ? 146.841 172.307 132.451 1.00 72.01  ? 187 THR   B O   1 
ATOM   1207 C CB  . THR   A 1 187 ? 149.627 172.539 134.185 1.00 72.01  ? 187 THR   B CB  1 
ATOM   1208 O OG1 . THR   A 1 187 ? 150.837 171.775 134.197 1.00 72.01  ? 187 THR   B OG1 1 
ATOM   1209 C CG2 . THR   A 1 187 ? 148.565 171.801 134.979 1.00 72.01  ? 187 THR   B CG2 1 
ATOM   1210 N N   . ARG   A 1 188 ? 147.414 174.429 132.920 1.00 69.74  ? 188 ARG   B N   1 
ATOM   1211 C CA  . ARG   A 1 188 ? 146.026 174.870 132.935 1.00 69.74  ? 188 ARG   B CA  1 
ATOM   1212 C C   . ARG   A 1 188 ? 145.373 174.665 131.576 1.00 69.74  ? 188 ARG   B C   1 
ATOM   1213 O O   . ARG   A 1 188 ? 144.258 174.141 131.479 1.00 69.74  ? 188 ARG   B O   1 
ATOM   1214 C CB  . ARG   A 1 188 ? 145.961 176.334 133.362 1.00 69.74  ? 188 ARG   B CB  1 
ATOM   1215 C CG  . ARG   A 1 188 ? 144.589 176.803 133.768 1.00 69.74  ? 188 ARG   B CG  1 
ATOM   1216 C CD  . ARG   A 1 188 ? 144.654 178.166 134.432 1.00 69.74  ? 188 ARG   B CD  1 
ATOM   1217 N NE  . ARG   A 1 188 ? 143.548 179.009 134.003 1.00 69.74  ? 188 ARG   B NE  1 
ATOM   1218 C CZ  . ARG   A 1 188 ? 143.549 179.715 132.880 1.00 69.74  ? 188 ARG   B CZ  1 
ATOM   1219 N NH1 . ARG   A 1 188 ? 144.605 179.693 132.084 1.00 69.74  ? 188 ARG   B NH1 1 
ATOM   1220 N NH2 . ARG   A 1 188 ? 142.497 180.451 132.558 1.00 69.74  ? 188 ARG   B NH2 1 
ATOM   1221 N N   . ALA   A 1 189 ? 146.071 175.050 130.509 1.00 64.83  ? 189 ALA   B N   1 
ATOM   1222 C CA  . ALA   A 1 189 ? 145.533 174.848 129.171 1.00 64.83  ? 189 ALA   B CA  1 
ATOM   1223 C C   . ALA   A 1 189 ? 145.402 173.368 128.842 1.00 64.83  ? 189 ALA   B C   1 
ATOM   1224 O O   . ALA   A 1 189 ? 144.417 172.948 128.218 1.00 64.83  ? 189 ALA   B O   1 
ATOM   1225 C CB  . ALA   A 1 189 ? 146.412 175.554 128.142 1.00 64.83  ? 189 ALA   B CB  1 
ATOM   1226 N N   . LYS   A 1 190 ? 146.382 172.560 129.247 1.00 61.06  ? 190 LYS   B N   1 
ATOM   1227 C CA  . LYS   A 1 190 ? 146.302 171.134 128.968 1.00 61.06  ? 190 LYS   B CA  1 
ATOM   1228 C C   . LYS   A 1 190 ? 145.089 170.512 129.639 1.00 61.06  ? 190 LYS   B C   1 
ATOM   1229 O O   . LYS   A 1 190 ? 144.345 169.737 129.018 1.00 61.06  ? 190 LYS   B O   1 
ATOM   1230 C CB  . LYS   A 1 190 ? 147.582 170.443 129.420 1.00 61.06  ? 190 LYS   B CB  1 
ATOM   1231 C CG  . LYS   A 1 190 ? 148.761 170.667 128.499 1.00 61.06  ? 190 LYS   B CG  1 
ATOM   1232 C CD  . LYS   A 1 190 ? 150.075 170.311 129.175 1.00 61.06  ? 190 LYS   B CD  1 
ATOM   1233 C CE  . LYS   A 1 190 ? 150.062 168.900 129.710 1.00 61.06  ? 190 LYS   B CE  1 
ATOM   1234 N NZ  . LYS   A 1 190 ? 151.310 168.189 129.360 1.00 61.06  ? 190 LYS   B NZ  1 
ATOM   1235 N N   . TYR   A 1 191 ? 144.853 170.858 130.899 1.00 62.70  ? 191 TYR   B N   1 
ATOM   1236 C CA  . TYR   A 1 191 ? 143.717 170.288 131.603 1.00 62.70  ? 191 TYR   B CA  1 
ATOM   1237 C C   . TYR   A 1 191 ? 142.398 170.839 131.083 1.00 62.70  ? 191 TYR   B C   1 
ATOM   1238 O O   . TYR   A 1 191 ? 141.386 170.131 131.110 1.00 62.70  ? 191 TYR   B O   1 
ATOM   1239 C CB  . TYR   A 1 191 ? 143.857 170.520 133.100 1.00 62.70  ? 191 TYR   B CB  1 
ATOM   1240 C CG  . TYR   A 1 191 ? 144.786 169.535 133.760 1.00 62.70  ? 191 TYR   B CG  1 
ATOM   1241 C CD1 . TYR   A 1 191 ? 144.309 168.590 134.640 1.00 62.70  ? 191 TYR   B CD1 1 
ATOM   1242 C CD2 . TYR   A 1 191 ? 146.143 169.552 133.495 1.00 62.70  ? 191 TYR   B CD2 1 
ATOM   1243 C CE1 . TYR   A 1 191 ? 145.156 167.690 135.240 1.00 62.70  ? 191 TYR   B CE1 1 
ATOM   1244 C CE2 . TYR   A 1 191 ? 146.998 168.660 134.089 1.00 62.70  ? 191 TYR   B CE2 1 
ATOM   1245 C CZ  . TYR   A 1 191 ? 146.502 167.730 134.960 1.00 62.70  ? 191 TYR   B CZ  1 
ATOM   1246 O OH  . TYR   A 1 191 ? 147.355 166.835 135.557 1.00 62.70  ? 191 TYR   B OH  1 
ATOM   1247 N N   . PHE   A 1 192 ? 142.383 172.071 130.573 1.00 57.34  ? 192 PHE   B N   1 
ATOM   1248 C CA  . PHE   A 1 192 ? 141.165 172.568 129.936 1.00 57.34  ? 192 PHE   B CA  1 
ATOM   1249 C C   . PHE   A 1 192 ? 140.832 171.769 128.689 1.00 57.34  ? 192 PHE   B C   1 
ATOM   1250 O O   . PHE   A 1 192 ? 139.667 171.416 128.455 1.00 57.34  ? 192 PHE   B O   1 
ATOM   1251 C CB  . PHE   A 1 192 ? 141.308 174.041 129.585 1.00 57.34  ? 192 PHE   B CB  1 
ATOM   1252 C CG  . PHE   A 1 192 ? 140.209 174.562 128.723 1.00 57.34  ? 192 PHE   B CG  1 
ATOM   1253 C CD1 . PHE   A 1 192 ? 138.997 174.906 129.268 1.00 57.34  ? 192 PHE   B CD1 1 
ATOM   1254 C CD2 . PHE   A 1 192 ? 140.393 174.731 127.371 1.00 57.34  ? 192 PHE   B CD2 1 
ATOM   1255 C CE1 . PHE   A 1 192 ? 137.987 175.386 128.485 1.00 57.34  ? 192 PHE   B CE1 1 
ATOM   1256 C CE2 . PHE   A 1 192 ? 139.380 175.214 126.584 1.00 57.34  ? 192 PHE   B CE2 1 
ATOM   1257 C CZ  . PHE   A 1 192 ? 138.177 175.542 127.146 1.00 57.34  ? 192 PHE   B CZ  1 
ATOM   1258 N N   . ILE   A 1 193 ? 141.840 171.495 127.862 1.00 52.41  ? 193 ILE   B N   1 
ATOM   1259 C CA  . ILE   A 1 193 ? 141.597 170.721 126.650 1.00 52.41  ? 193 ILE   B CA  1 
ATOM   1260 C C   . ILE   A 1 193 ? 141.130 169.317 127.001 1.00 52.41  ? 193 ILE   B C   1 
ATOM   1261 O O   . ILE   A 1 193 ? 140.257 168.755 126.332 1.00 52.41  ? 193 ILE   B O   1 
ATOM   1262 C CB  . ILE   A 1 193 ? 142.846 170.710 125.757 1.00 52.41  ? 193 ILE   B CB  1 
ATOM   1263 C CG1 . ILE   A 1 193 ? 143.126 172.115 125.237 1.00 52.41  ? 193 ILE   B CG1 1 
ATOM   1264 C CG2 . ILE   A 1 193 ? 142.668 169.759 124.606 1.00 52.41  ? 193 ILE   B CG2 1 
ATOM   1265 C CD1 . ILE   A 1 193 ? 144.444 172.255 124.541 1.00 52.41  ? 193 ILE   B CD1 1 
ATOM   1266 N N   . ARG   A 1 194 ? 141.684 168.733 128.062 1.00 50.88  ? 194 ARG   B N   1 
ATOM   1267 C CA  . ARG   A 1 194 ? 141.167 167.445 128.523 1.00 50.88  ? 194 ARG   B CA  1 
ATOM   1268 C C   . ARG   A 1 194 ? 139.712 167.548 128.956 1.00 50.88  ? 194 ARG   B C   1 
ATOM   1269 O O   . ARG   A 1 194 ? 138.901 166.662 128.651 1.00 50.88  ? 194 ARG   B O   1 
ATOM   1270 C CB  . ARG   A 1 194 ? 142.003 166.916 129.677 1.00 50.88  ? 194 ARG   B CB  1 
ATOM   1271 C CG  . ARG   A 1 194 ? 141.427 165.678 130.282 1.00 50.88  ? 194 ARG   B CG  1 
ATOM   1272 C CD  . ARG   A 1 194 ? 142.175 165.274 131.526 1.00 50.88  ? 194 ARG   B CD  1 
ATOM   1273 N NE  . ARG   A 1 194 ? 143.508 164.794 131.225 1.00 50.88  ? 194 ARG   B NE  1 
ATOM   1274 C CZ  . ARG   A 1 194 ? 144.403 164.473 132.147 1.00 50.88  ? 194 ARG   B CZ  1 
ATOM   1275 N NH1 . ARG   A 1 194 ? 144.093 164.578 133.429 1.00 50.88  ? 194 ARG   B NH1 1 
ATOM   1276 N NH2 . ARG   A 1 194 ? 145.603 164.043 131.789 1.00 50.88  ? 194 ARG   B NH2 1 
ATOM   1277 N N   . LYS   A 1 195 ? 139.369 168.615 129.677 1.00 51.21  ? 195 LYS   B N   1 
ATOM   1278 C CA  . LYS   A 1 195 ? 138.010 168.772 130.179 1.00 51.21  ? 195 LYS   B CA  1 
ATOM   1279 C C   . LYS   A 1 195 ? 137.012 168.895 129.041 1.00 51.21  ? 195 LYS   B C   1 
ATOM   1280 O O   . LYS   A 1 195 ? 135.891 168.385 129.132 1.00 51.21  ? 195 LYS   B O   1 
ATOM   1281 C CB  . LYS   A 1 195 ? 137.925 169.993 131.091 1.00 51.21  ? 195 LYS   B CB  1 
ATOM   1282 N N   . GLU   A 1 196 ? 137.400 169.570 127.961 1.00 52.19  ? 196 GLU   B N   1 
ATOM   1283 C CA  . GLU   A 1 196 ? 136.473 169.784 126.858 1.00 52.19  ? 196 GLU   B CA  1 
ATOM   1284 C C   . GLU   A 1 196 ? 136.046 168.485 126.185 1.00 52.19  ? 196 GLU   B C   1 
ATOM   1285 O O   . GLU   A 1 196 ? 135.029 168.473 125.489 1.00 52.19  ? 196 GLU   B O   1 
ATOM   1286 C CB  . GLU   A 1 196 ? 137.098 170.720 125.834 1.00 52.19  ? 196 GLU   B CB  1 
ATOM   1287 C CG  . GLU   A 1 196 ? 137.107 172.166 126.262 1.00 52.19  ? 196 GLU   B CG  1 
ATOM   1288 C CD  . GLU   A 1 196 ? 135.731 172.791 126.236 1.00 52.19  ? 196 GLU   B CD  1 
ATOM   1289 O OE1 . GLU   A 1 196 ? 135.412 173.485 125.251 1.00 52.19  ? 196 GLU   B OE1 1 
ATOM   1290 O OE2 . GLU   A 1 196 ? 134.968 172.596 127.204 1.00 52.19  ? 196 GLU   B OE2 1 
ATOM   1291 N N   . PHE   A 1 197 ? 136.799 167.400 126.358 1.00 47.56  ? 197 PHE   B N   1 
ATOM   1292 C CA  . PHE   A 1 197 ? 136.421 166.082 125.859 1.00 47.56  ? 197 PHE   B CA  1 
ATOM   1293 C C   . PHE   A 1 197 ? 135.805 165.209 126.936 1.00 47.56  ? 197 PHE   B C   1 
ATOM   1294 O O   . PHE   A 1 197 ? 134.870 164.446 126.664 1.00 47.56  ? 197 PHE   B O   1 
ATOM   1295 C CB  . PHE   A 1 197 ? 137.633 165.349 125.291 1.00 47.56  ? 197 PHE   B CB  1 
ATOM   1296 C CG  . PHE   A 1 197 ? 138.160 165.922 124.024 1.00 47.56  ? 197 PHE   B CG  1 
ATOM   1297 C CD1 . PHE   A 1 197 ? 139.089 166.930 124.045 1.00 47.56  ? 197 PHE   B CD1 1 
ATOM   1298 C CD2 . PHE   A 1 197 ? 137.746 165.435 122.810 1.00 47.56  ? 197 PHE   B CD2 1 
ATOM   1299 C CE1 . PHE   A 1 197 ? 139.583 167.446 122.893 1.00 47.56  ? 197 PHE   B CE1 1 
ATOM   1300 C CE2 . PHE   A 1 197 ? 138.237 165.955 121.650 1.00 47.56  ? 197 PHE   B CE2 1 
ATOM   1301 C CZ  . PHE   A 1 197 ? 139.159 166.959 121.693 1.00 47.56  ? 197 PHE   B CZ  1 
ATOM   1302 N N   . VAL   A 1 198 ? 136.315 165.301 128.161 1.00 50.35  ? 198 VAL   B N   1 
ATOM   1303 C CA  . VAL   A 1 198 ? 135.769 164.494 129.238 1.00 50.35  ? 198 VAL   B CA  1 
ATOM   1304 C C   . VAL   A 1 198 ? 134.341 164.912 129.568 1.00 50.35  ? 198 VAL   B C   1 
ATOM   1305 O O   . VAL   A 1 198 ? 133.505 164.061 129.899 1.00 50.35  ? 198 VAL   B O   1 
ATOM   1306 C CB  . VAL   A 1 198 ? 136.702 164.560 130.458 1.00 50.35  ? 198 VAL   B CB  1 
ATOM   1307 C CG1 . VAL   A 1 198 ? 135.985 164.103 131.722 1.00 50.35  ? 198 VAL   B CG1 1 
ATOM   1308 C CG2 . VAL   A 1 198 ? 137.922 163.704 130.206 1.00 50.35  ? 198 VAL   B CG2 1 
ATOM   1309 N N   . ASP   A 1 199 ? 134.016 166.205 129.466 1.00 53.41  ? 199 ASP   B N   1 
ATOM   1310 C CA  . ASP   A 1 199 ? 132.631 166.616 129.677 1.00 53.41  ? 199 ASP   B CA  1 
ATOM   1311 C C   . ASP   A 1 199 ? 131.718 166.118 128.561 1.00 53.41  ? 199 ASP   B C   1 
ATOM   1312 O O   . ASP   A 1 199 ? 130.525 165.900 128.791 1.00 53.41  ? 199 ASP   B O   1 
ATOM   1313 C CB  . ASP   A 1 199 ? 132.535 168.136 129.818 1.00 53.41  ? 199 ASP   B CB  1 
ATOM   1314 C CG  . ASP   A 1 199 ? 132.971 168.876 128.569 1.00 53.41  ? 199 ASP   B CG  1 
ATOM   1315 O OD1 . ASP   A 1 199 ? 133.390 168.222 127.595 1.00 53.41  ? 199 ASP   B OD1 1 
ATOM   1316 O OD2 . ASP   A 1 199 ? 132.895 170.123 128.563 1.00 53.41  ? 199 ASP   B OD2 1 
ATOM   1317 N N   . ILE   A 1 200 ? 132.251 165.936 127.353 1.00 49.00  ? 200 ILE   B N   1 
ATOM   1318 C CA  . ILE   A 1 200 ? 131.501 165.244 126.308 1.00 49.00  ? 200 ILE   B CA  1 
ATOM   1319 C C   . ILE   A 1 200 ? 131.238 163.805 126.722 1.00 49.00  ? 200 ILE   B C   1 
ATOM   1320 O O   . ILE   A 1 200 ? 130.121 163.293 126.594 1.00 49.00  ? 200 ILE   B O   1 
ATOM   1321 C CB  . ILE   A 1 200 ? 132.263 165.308 124.972 1.00 49.00  ? 200 ILE   B CB  1 
ATOM   1322 C CG1 . ILE   A 1 200 ? 132.257 166.722 124.409 1.00 49.00  ? 200 ILE   B CG1 1 
ATOM   1323 C CG2 . ILE   A 1 200 ? 131.686 164.340 123.980 1.00 49.00  ? 200 ILE   B CG2 1 
ATOM   1324 C CD1 . ILE   A 1 200 ? 133.212 166.906 123.277 1.00 49.00  ? 200 ILE   B CD1 1 
ATOM   1325 N N   . SER   A 1 201 ? 132.271 163.132 127.230 1.00 50.67  ? 201 SER   B N   1 
ATOM   1326 C CA  . SER   A 1 201 ? 132.153 161.707 127.517 1.00 50.67  ? 201 SER   B CA  1 
ATOM   1327 C C   . SER   A 1 201 ? 131.320 161.446 128.760 1.00 50.67  ? 201 SER   B C   1 
ATOM   1328 O O   . SER   A 1 201 ? 130.490 160.532 128.774 1.00 50.67  ? 201 SER   B O   1 
ATOM   1329 C CB  . SER   A 1 201 ? 133.538 161.090 127.676 1.00 50.67  ? 201 SER   B CB  1 
ATOM   1330 O OG  . SER   A 1 201 ? 133.466 159.871 128.393 1.00 50.67  ? 201 SER   B OG  1 
ATOM   1331 N N   . THR   A 1 202 ? 131.528 162.230 129.817 1.00 54.62  ? 202 THR   B N   1 
ATOM   1332 C CA  . THR   A 1 202 ? 130.903 161.988 131.111 1.00 54.62  ? 202 THR   B CA  1 
ATOM   1333 C C   . THR   A 1 202 ? 129.570 162.699 131.262 1.00 54.62  ? 202 THR   B C   1 
ATOM   1334 O O   . THR   A 1 202 ? 129.172 163.027 132.386 1.00 54.62  ? 202 THR   B O   1 
ATOM   1335 C CB  . THR   A 1 202 ? 131.848 162.399 132.239 1.00 54.62  ? 202 THR   B CB  1 
ATOM   1336 O OG1 . THR   A 1 202 ? 132.216 163.774 132.078 1.00 54.62  ? 202 THR   B OG1 1 
ATOM   1337 C CG2 . THR   A 1 202 ? 133.101 161.538 132.222 1.00 54.62  ? 202 THR   B CG2 1 
ATOM   1338 N N   . ALA   A 1 203 ? 128.867 162.952 130.161 1.00 57.57  ? 203 ALA   B N   1 
ATOM   1339 C CA  . ALA   A 1 203 ? 127.576 163.622 130.207 1.00 57.57  ? 203 ALA   B CA  1 
ATOM   1340 C C   . ALA   A 1 203 ? 126.420 162.640 130.060 1.00 57.57  ? 203 ALA   B C   1 
ATOM   1341 O O   . ALA   A 1 203 ? 125.570 162.539 130.950 1.00 57.57  ? 203 ALA   B O   1 
ATOM   1342 C CB  . ALA   A 1 203 ? 127.505 164.699 129.117 1.00 57.57  ? 203 ALA   B CB  1 
ATOM   1343 N N   . SER   A 1 204 ? 126.372 161.911 128.948 1.00 64.93  ? 204 SER   B N   1 
ATOM   1344 C CA  . SER   A 1 204 ? 125.294 160.957 128.687 1.00 64.93  ? 204 SER   B CA  1 
ATOM   1345 C C   . SER   A 1 204 ? 125.913 159.700 128.078 1.00 64.93  ? 204 SER   B C   1 
ATOM   1346 O O   . SER   A 1 204 ? 126.044 159.589 126.857 1.00 64.93  ? 204 SER   B O   1 
ATOM   1347 C CB  . SER   A 1 204 ? 124.237 161.566 127.776 1.00 64.93  ? 204 SER   B CB  1 
ATOM   1348 O OG  . SER   A 1 204 ? 124.605 161.440 126.414 1.00 64.93  ? 204 SER   B OG  1 
ATOM   1349 N N   . GLY   A 1 205 ? 126.286 158.755 128.938 1.00 67.98  ? 205 GLY   B N   1 
ATOM   1350 C CA  . GLY   A 1 205 ? 126.837 157.496 128.482 1.00 67.98  ? 205 GLY   B CA  1 
ATOM   1351 C C   . GLY   A 1 205 ? 126.295 156.297 129.231 1.00 67.98  ? 205 GLY   B C   1 
ATOM   1352 O O   . GLY   A 1 205 ? 126.475 155.153 128.803 1.00 67.98  ? 205 GLY   B O   1 
ATOM   1353 N N   . ASP   A 1 206 ? 125.636 156.554 130.360 1.00 70.18  ? 206 ASP   B N   1 
ATOM   1354 C CA  . ASP   A 1 206 ? 124.999 155.529 131.187 1.00 70.18  ? 206 ASP   B CA  1 
ATOM   1355 C C   . ASP   A 1 206 ? 125.980 154.472 131.693 1.00 70.18  ? 206 ASP   B C   1 
ATOM   1356 O O   . ASP   A 1 206 ? 125.563 153.384 132.101 1.00 70.18  ? 206 ASP   B O   1 
ATOM   1357 C CB  . ASP   A 1 206 ? 123.842 154.855 130.439 1.00 70.18  ? 206 ASP   B CB  1 
ATOM   1358 N N   . GLY   A 1 207 ? 127.280 154.760 131.678 1.00 62.98  ? 207 GLY   B N   1 
ATOM   1359 C CA  . GLY   A 1 207 ? 128.250 153.837 132.234 1.00 62.98  ? 207 GLY   B CA  1 
ATOM   1360 C C   . GLY   A 1 207 ? 128.544 152.605 131.411 1.00 62.98  ? 207 GLY   B C   1 
ATOM   1361 O O   . GLY   A 1 207 ? 129.161 151.671 131.929 1.00 62.98  ? 207 GLY   B O   1 
ATOM   1362 N N   . ARG   A 1 208 ? 128.128 152.564 130.143 1.00 57.85  ? 208 ARG   B N   1 
ATOM   1363 C CA  . ARG   A 1 208 ? 128.388 151.396 129.307 1.00 57.85  ? 208 ARG   B CA  1 
ATOM   1364 C C   . ARG   A 1 208 ? 129.782 151.419 128.698 1.00 57.85  ? 208 ARG   B C   1 
ATOM   1365 O O   . ARG   A 1 208 ? 130.325 150.359 128.372 1.00 57.85  ? 208 ARG   B O   1 
ATOM   1366 C CB  . ARG   A 1 208 ? 127.341 151.300 128.198 1.00 57.85  ? 208 ARG   B CB  1 
ATOM   1367 N N   . HIS   A 1 209 ? 130.370 152.600 128.534 1.00 47.42  ? 209 HIS   B N   1 
ATOM   1368 C CA  . HIS   A 1 209 ? 131.729 152.729 128.031 1.00 47.42  ? 209 HIS   B CA  1 
ATOM   1369 C C   . HIS   A 1 209 ? 132.305 154.047 128.513 1.00 47.42  ? 209 HIS   B C   1 
ATOM   1370 O O   . HIS   A 1 209 ? 131.575 155.022 128.700 1.00 47.42  ? 209 HIS   B O   1 
ATOM   1371 C CB  . HIS   A 1 209 ? 131.773 152.640 126.506 1.00 47.42  ? 209 HIS   B CB  1 
ATOM   1372 C CG  . HIS   A 1 209 ? 131.010 153.718 125.809 1.00 47.42  ? 209 HIS   B CG  1 
ATOM   1373 N ND1 . HIS   A 1 209 ? 129.695 154.000 126.095 1.00 47.42  ? 209 HIS   B ND1 1 
ATOM   1374 C CD2 . HIS   A 1 209 ? 131.362 154.550 124.802 1.00 47.42  ? 209 HIS   B CD2 1 
ATOM   1375 C CE1 . HIS   A 1 209 ? 129.277 154.978 125.314 1.00 47.42  ? 209 HIS   B CE1 1 
ATOM   1376 N NE2 . HIS   A 1 209 ? 130.269 155.328 124.519 1.00 47.42  ? 209 HIS   B NE2 1 
ATOM   1377 N N   . ILE   A 1 210 ? 133.621 154.072 128.714 1.00 44.40  ? 210 ILE   B N   1 
ATOM   1378 C CA  . ILE   A 1 210 ? 134.298 155.242 129.252 1.00 44.40  ? 210 ILE   B CA  1 
ATOM   1379 C C   . ILE   A 1 210 ? 135.474 155.619 128.358 1.00 44.40  ? 210 ILE   B C   1 
ATOM   1380 O O   . ILE   A 1 210 ? 135.904 154.853 127.498 1.00 44.40  ? 210 ILE   B O   1 
ATOM   1381 C CB  . ILE   A 1 210 ? 134.759 155.030 130.705 1.00 44.40  ? 210 ILE   B CB  1 
ATOM   1382 C CG1 . ILE   A 1 210 ? 135.765 153.895 130.794 1.00 44.40  ? 210 ILE   B CG1 1 
ATOM   1383 C CG2 . ILE   A 1 210 ? 133.570 154.761 131.613 1.00 44.40  ? 210 ILE   B CG2 1 
ATOM   1384 C CD1 . ILE   A 1 210 ? 136.413 153.805 132.154 1.00 44.40  ? 210 ILE   B CD1 1 
ATOM   1385 N N   . CYS   A 1 211 ? 135.976 156.833 128.566 1.00 42.85  ? 211 CYS   B N   1 
ATOM   1386 C CA  . CYS   A 1 211 ? 137.057 157.409 127.784 1.00 42.85  ? 211 CYS   B CA  1 
ATOM   1387 C C   . CYS   A 1 211 ? 138.266 157.635 128.676 1.00 42.85  ? 211 CYS   B C   1 
ATOM   1388 O O   . CYS   A 1 211 ? 138.159 158.300 129.711 1.00 42.85  ? 211 CYS   B O   1 
ATOM   1389 C CB  . CYS   A 1 211 ? 136.626 158.725 127.153 1.00 42.85  ? 211 CYS   B CB  1 
ATOM   1390 S SG  . CYS   A 1 211 ? 137.888 159.541 126.182 1.00 42.85  ? 211 CYS   B SG  1 
ATOM   1391 N N   . TYR   A 1 212 ? 139.411 157.084 128.278 1.00 42.84  ? 212 TYR   B N   1 
ATOM   1392 C CA  . TYR   A 1 212 ? 140.645 157.250 129.027 1.00 42.84  ? 212 TYR   B CA  1 
ATOM   1393 C C   . TYR   A 1 212 ? 141.508 158.279 128.323 1.00 42.84  ? 212 TYR   B C   1 
ATOM   1394 O O   . TYR   A 1 212 ? 142.048 157.982 127.248 1.00 42.84  ? 212 TYR   B O   1 
ATOM   1395 C CB  . TYR   A 1 212 ? 141.395 155.929 129.136 1.00 42.84  ? 212 TYR   B CB  1 
ATOM   1396 C CG  . TYR   A 1 212 ? 140.598 154.774 129.659 1.00 42.84  ? 212 TYR   B CG  1 
ATOM   1397 C CD1 . TYR   A 1 212 ? 140.602 154.467 131.000 1.00 42.84  ? 212 TYR   B CD1 1 
ATOM   1398 C CD2 . TYR   A 1 212 ? 139.861 153.975 128.812 1.00 42.84  ? 212 TYR   B CD2 1 
ATOM   1399 C CE1 . TYR   A 1 212 ? 139.882 153.405 131.486 1.00 42.84  ? 212 TYR   B CE1 1 
ATOM   1400 C CE2 . TYR   A 1 212 ? 139.136 152.913 129.289 1.00 42.84  ? 212 TYR   B CE2 1 
ATOM   1401 C CZ  . TYR   A 1 212 ? 139.151 152.632 130.626 1.00 42.84  ? 212 TYR   B CZ  1 
ATOM   1402 O OH  . TYR   A 1 212 ? 138.431 151.570 131.110 1.00 42.84  ? 212 TYR   B OH  1 
ATOM   1403 N N   . PRO   A 1 213 ? 141.674 159.479 128.862 1.00 41.56  ? 213 PRO   B N   1 
ATOM   1404 C CA  . PRO   A 1 213 ? 142.531 160.465 128.203 1.00 41.56  ? 213 PRO   B CA  1 
ATOM   1405 C C   . PRO   A 1 213 ? 143.992 160.292 128.573 1.00 41.56  ? 213 PRO   B C   1 
ATOM   1406 O O   . PRO   A 1 213 ? 144.332 159.938 129.705 1.00 41.56  ? 213 PRO   B O   1 
ATOM   1407 C CB  . PRO   A 1 213 ? 141.988 161.801 128.714 1.00 41.56  ? 213 PRO   B CB  1 
ATOM   1408 C CG  . PRO   A 1 213 ? 140.688 161.481 129.360 1.00 41.56  ? 213 PRO   B CG  1 
ATOM   1409 C CD  . PRO   A 1 213 ? 140.819 160.102 129.874 1.00 41.56  ? 213 PRO   B CD  1 
ATOM   1410 N N   . HIS   A 1 214 ? 144.858 160.541 127.599 1.00 43.75  ? 214 HIS   B N   1 
ATOM   1411 C CA  . HIS   A 1 214 ? 146.290 160.585 127.829 1.00 43.75  ? 214 HIS   B CA  1 
ATOM   1412 C C   . HIS   A 1 214 ? 146.891 161.714 127.010 1.00 43.75  ? 214 HIS   B C   1 
ATOM   1413 O O   . HIS   A 1 214 ? 146.280 162.223 126.070 1.00 43.75  ? 214 HIS   B O   1 
ATOM   1414 C CB  . HIS   A 1 214 ? 146.997 159.278 127.465 1.00 43.75  ? 214 HIS   B CB  1 
ATOM   1415 C CG  . HIS   A 1 214 ? 146.373 158.057 128.053 1.00 43.75  ? 214 HIS   B CG  1 
ATOM   1416 N ND1 . HIS   A 1 214 ? 146.080 157.940 129.392 1.00 43.75  ? 214 HIS   B ND1 1 
ATOM   1417 C CD2 . HIS   A 1 214 ? 146.022 156.881 127.486 1.00 43.75  ? 214 HIS   B CD2 1 
ATOM   1418 C CE1 . HIS   A 1 214 ? 145.552 156.752 129.621 1.00 43.75  ? 214 HIS   B CE1 1 
ATOM   1419 N NE2 . HIS   A 1 214 ? 145.504 156.091 128.480 1.00 43.75  ? 214 HIS   B NE2 1 
ATOM   1420 N N   . PHE   A 1 215 ? 148.107 162.091 127.379 1.00 51.38  ? 215 PHE   B N   1 
ATOM   1421 C CA  . PHE   A 1 215 ? 148.854 163.150 126.724 1.00 51.38  ? 215 PHE   B CA  1 
ATOM   1422 C C   . PHE   A 1 215 ? 150.135 162.565 126.155 1.00 51.38  ? 215 PHE   B C   1 
ATOM   1423 O O   . PHE   A 1 215 ? 150.738 161.681 126.765 1.00 51.38  ? 215 PHE   B O   1 
ATOM   1424 C CB  . PHE   A 1 215 ? 149.185 164.265 127.708 1.00 51.38  ? 215 PHE   B CB  1 
ATOM   1425 C CG  . PHE   A 1 215 ? 148.149 165.336 127.786 1.00 51.38  ? 215 PHE   B CG  1 
ATOM   1426 C CD1 . PHE   A 1 215 ? 148.129 166.363 126.868 1.00 51.38  ? 215 PHE   B CD1 1 
ATOM   1427 C CD2 . PHE   A 1 215 ? 147.212 165.333 128.788 1.00 51.38  ? 215 PHE   B CD2 1 
ATOM   1428 C CE1 . PHE   A 1 215 ? 147.184 167.348 126.945 1.00 51.38  ? 215 PHE   B CE1 1 
ATOM   1429 C CE2 . PHE   A 1 215 ? 146.270 166.319 128.863 1.00 51.38  ? 215 PHE   B CE2 1 
ATOM   1430 C CZ  . PHE   A 1 215 ? 146.256 167.324 127.943 1.00 51.38  ? 215 PHE   B CZ  1 
ATOM   1431 N N   . THR   A 1 216 ? 150.555 163.054 124.991 1.00 58.43  ? 216 THR   B N   1 
ATOM   1432 C CA  . THR   A 1 216 ? 151.700 162.479 124.300 1.00 58.43  ? 216 THR   B CA  1 
ATOM   1433 C C   . THR   A 1 216 ? 152.572 163.579 123.717 1.00 58.43  ? 216 THR   B C   1 
ATOM   1434 O O   . THR   A 1 216 ? 152.255 164.769 123.805 1.00 58.43  ? 216 THR   B O   1 
ATOM   1435 C CB  . THR   A 1 216 ? 151.260 161.517 123.200 1.00 58.43  ? 216 THR   B CB  1 
ATOM   1436 O OG1 . THR   A 1 216 ? 150.159 162.081 122.482 1.00 58.43  ? 216 THR   B OG1 1 
ATOM   1437 C CG2 . THR   A 1 216 ? 150.848 160.206 123.803 1.00 58.43  ? 216 THR   B CG2 1 
ATOM   1438 N N   . CYS   A 1 217 ? 153.685 163.166 123.109 1.00 65.56  ? 217 CYS   B N   1 
ATOM   1439 C CA  . CYS   A 1 217 ? 154.626 164.113 122.534 1.00 65.56  ? 217 CYS   B CA  1 
ATOM   1440 C C   . CYS   A 1 217 ? 155.202 163.687 121.191 1.00 65.56  ? 217 CYS   B C   1 
ATOM   1441 O O   . CYS   A 1 217 ? 156.075 164.390 120.673 1.00 65.56  ? 217 CYS   B O   1 
ATOM   1442 C CB  . CYS   A 1 217 ? 155.782 164.374 123.512 1.00 65.56  ? 217 CYS   B CB  1 
ATOM   1443 S SG  . CYS   A 1 217 ? 157.073 163.110 123.500 1.00 65.56  ? 217 CYS   B SG  1 
ATOM   1444 N N   . ALA   A 1 218 ? 154.773 162.556 120.629 1.00 65.96  ? 218 ALA   B N   1 
ATOM   1445 C CA  . ALA   A 1 218 ? 155.217 162.089 119.317 1.00 65.96  ? 218 ALA   B CA  1 
ATOM   1446 C C   . ALA   A 1 218 ? 156.707 161.758 119.289 1.00 65.96  ? 218 ALA   B C   1 
ATOM   1447 O O   . ALA   A 1 218 ? 157.241 161.368 118.246 1.00 65.96  ? 218 ALA   B O   1 
ATOM   1448 C CB  . ALA   A 1 218 ? 154.886 163.119 118.233 1.00 65.96  ? 218 ALA   B CB  1 
ATOM   1449 N N   . VAL   A 1 219 ? 157.385 161.910 120.423 1.00 62.36  ? 219 VAL   B N   1 
ATOM   1450 C CA  . VAL   A 1 219 ? 158.784 161.526 120.559 1.00 62.36  ? 219 VAL   B CA  1 
ATOM   1451 C C   . VAL   A 1 219 ? 158.912 160.652 121.795 1.00 62.36  ? 219 VAL   B C   1 
ATOM   1452 O O   . VAL   A 1 219 ? 159.945 160.665 122.473 1.00 62.36  ? 219 VAL   B O   1 
ATOM   1453 C CB  . VAL   A 1 219 ? 159.705 162.755 120.648 1.00 62.36  ? 219 VAL   B CB  1 
ATOM   1454 N N   . ASP   A 1 220 ? 157.850 159.915 122.111 1.00 59.76  ? 220 ASP   B N   1 
ATOM   1455 C CA  . ASP   A 1 220 ? 157.799 159.053 123.282 1.00 59.76  ? 220 ASP   B CA  1 
ATOM   1456 C C   . ASP   A 1 220 ? 157.705 157.606 122.831 1.00 59.76  ? 220 ASP   B C   1 
ATOM   1457 O O   . ASP   A 1 220 ? 156.796 157.244 122.079 1.00 59.76  ? 220 ASP   B O   1 
ATOM   1458 C CB  . ASP   A 1 220 ? 156.610 159.406 124.178 1.00 59.76  ? 220 ASP   B CB  1 
ATOM   1459 N N   . THR   A 1 221 ? 158.644 156.787 123.289 1.00 59.34  ? 221 THR   B N   1 
ATOM   1460 C CA  . THR   A 1 221 ? 158.691 155.389 122.893 1.00 59.34  ? 221 THR   B CA  1 
ATOM   1461 C C   . THR   A 1 221 ? 157.828 154.492 123.766 1.00 59.34  ? 221 THR   B C   1 
ATOM   1462 O O   . THR   A 1 221 ? 157.472 153.390 123.334 1.00 59.34  ? 221 THR   B O   1 
ATOM   1463 C CB  . THR   A 1 221 ? 160.132 154.879 122.926 1.00 59.34  ? 221 THR   B CB  1 
ATOM   1464 O OG1 . THR   A 1 221 ? 160.175 153.534 122.437 1.00 59.34  ? 221 THR   B OG1 1 
ATOM   1465 C CG2 . THR   A 1 221 ? 160.674 154.914 124.342 1.00 59.34  ? 221 THR   B CG2 1 
ATOM   1466 N N   . GLU   A 1 222 ? 157.487 154.929 124.974 1.00 55.77  ? 222 GLU   B N   1 
ATOM   1467 C CA  . GLU   A 1 222 ? 156.678 154.129 125.889 1.00 55.77  ? 222 GLU   B CA  1 
ATOM   1468 C C   . GLU   A 1 222 ? 155.193 154.392 125.685 1.00 55.77  ? 222 GLU   B C   1 
ATOM   1469 O O   . GLU   A 1 222 ? 154.473 154.752 126.611 1.00 55.77  ? 222 GLU   B O   1 
ATOM   1470 C CB  . GLU   A 1 222 ? 157.091 154.415 127.327 1.00 55.77  ? 222 GLU   B CB  1 
ATOM   1471 N N   . ASN   A 1 223 ? 154.726 154.209 124.454 1.00 53.22  ? 223 ASN   B N   1 
ATOM   1472 C CA  . ASN   A 1 223 ? 153.376 154.597 124.080 1.00 53.22  ? 223 ASN   B CA  1 
ATOM   1473 C C   . ASN   A 1 223 ? 152.456 153.417 123.819 1.00 53.22  ? 223 ASN   B C   1 
ATOM   1474 O O   . ASN   A 1 223 ? 151.251 153.621 123.655 1.00 53.22  ? 223 ASN   B O   1 
ATOM   1475 C CB  . ASN   A 1 223 ? 153.417 155.494 122.839 1.00 53.22  ? 223 ASN   B CB  1 
ATOM   1476 C CG  . ASN   A 1 223 ? 152.271 156.464 122.792 1.00 53.22  ? 223 ASN   B CG  1 
ATOM   1477 O OD1 . ASN   A 1 223 ? 152.152 157.338 123.643 1.00 53.22  ? 223 ASN   B OD1 1 
ATOM   1478 N ND2 . ASN   A 1 223 ? 151.427 156.327 121.780 1.00 53.22  ? 223 ASN   B ND2 1 
ATOM   1479 N N   . ALA   A 1 224 ? 152.989 152.199 123.760 1.00 51.50  ? 224 ALA   B N   1 
ATOM   1480 C CA  . ALA   A 1 224 ? 152.158 151.011 123.696 1.00 51.50  ? 224 ALA   B CA  1 
ATOM   1481 C C   . ALA   A 1 224 ? 151.802 150.480 125.077 1.00 51.50  ? 224 ALA   B C   1 
ATOM   1482 O O   . ALA   A 1 224 ? 150.796 149.779 125.215 1.00 51.50  ? 224 ALA   B O   1 
ATOM   1483 C CB  . ALA   A 1 224 ? 152.858 149.923 122.886 1.00 51.50  ? 224 ALA   B CB  1 
ATOM   1484 N N   . ARG   A 1 225 ? 152.598 150.805 126.098 1.00 52.91  ? 225 ARG   B N   1 
ATOM   1485 C CA  . ARG   A 1 225 ? 152.248 150.414 127.456 1.00 52.91  ? 225 ARG   B CA  1 
ATOM   1486 C C   . ARG   A 1 225 ? 150.944 151.059 127.889 1.00 52.91  ? 225 ARG   B C   1 
ATOM   1487 O O   . ARG   A 1 225 ? 150.149 150.445 128.609 1.00 52.91  ? 225 ARG   B O   1 
ATOM   1488 C CB  . ARG   A 1 225 ? 153.363 150.790 128.427 1.00 52.91  ? 225 ARG   B CB  1 
ATOM   1489 C CG  . ARG   A 1 225 ? 154.671 150.082 128.188 1.00 52.91  ? 225 ARG   B CG  1 
ATOM   1490 C CD  . ARG   A 1 225 ? 154.523 148.595 128.387 1.00 52.91  ? 225 ARG   B CD  1 
ATOM   1491 N NE  . ARG   A 1 225 ? 153.957 148.276 129.690 1.00 52.91  ? 225 ARG   B NE  1 
ATOM   1492 C CZ  . ARG   A 1 225 ? 154.000 147.068 130.240 1.00 52.91  ? 225 ARG   B CZ  1 
ATOM   1493 N NH1 . ARG   A 1 225 ? 154.586 146.070 129.600 1.00 52.91  ? 225 ARG   B NH1 1 
ATOM   1494 N NH2 . ARG   A 1 225 ? 153.458 146.859 131.430 1.00 52.91  ? 225 ARG   B NH2 1 
ATOM   1495 N N   . ARG   A 1 226 ? 150.709 152.303 127.475 1.00 50.86  ? 226 ARG   B N   1 
ATOM   1496 C CA  . ARG   A 1 226 ? 149.470 152.971 127.851 1.00 50.86  ? 226 ARG   B CA  1 
ATOM   1497 C C   . ARG   A 1 226 ? 148.257 152.304 127.210 1.00 50.86  ? 226 ARG   B C   1 
ATOM   1498 O O   . ARG   A 1 226 ? 147.239 152.077 127.881 1.00 50.86  ? 226 ARG   B O   1 
ATOM   1499 C CB  . ARG   A 1 226 ? 149.547 154.445 127.482 1.00 50.86  ? 226 ARG   B CB  1 
ATOM   1500 C CG  . ARG   A 1 226 ? 150.579 155.198 128.284 1.00 50.86  ? 226 ARG   B CG  1 
ATOM   1501 C CD  . ARG   A 1 226 ? 150.195 156.646 128.438 1.00 50.86  ? 226 ARG   B CD  1 
ATOM   1502 N NE  . ARG   A 1 226 ? 151.360 157.508 128.569 1.00 50.86  ? 226 ARG   B NE  1 
ATOM   1503 C CZ  . ARG   A 1 226 ? 151.818 158.287 127.600 1.00 50.86  ? 226 ARG   B CZ  1 
ATOM   1504 N NH1 . ARG   A 1 226 ? 151.213 158.304 126.426 1.00 50.86  ? 226 ARG   B NH1 1 
ATOM   1505 N NH2 . ARG   A 1 226 ? 152.883 159.046 127.804 1.00 50.86  ? 226 ARG   B NH2 1 
ATOM   1506 N N   . ILE   A 1 227 ? 148.350 151.971 125.923 1.00 48.71  ? 227 ILE   B N   1 
ATOM   1507 C CA  . ILE   A 1 227 ? 147.279 151.232 125.266 1.00 48.71  ? 227 ILE   B CA  1 
ATOM   1508 C C   . ILE   A 1 227 ? 147.062 149.898 125.956 1.00 48.71  ? 227 ILE   B C   1 
ATOM   1509 O O   . ILE   A 1 227 ? 145.924 149.471 126.173 1.00 48.71  ? 227 ILE   B O   1 
ATOM   1510 C CB  . ILE   A 1 227 ? 147.593 151.040 123.774 1.00 48.71  ? 227 ILE   B CB  1 
ATOM   1511 C CG1 . ILE   A 1 227 ? 147.720 152.378 123.060 1.00 48.71  ? 227 ILE   B CG1 1 
ATOM   1512 C CG2 . ILE   A 1 227 ? 146.524 150.218 123.130 1.00 48.71  ? 227 ILE   B CG2 1 
ATOM   1513 C CD1 . ILE   A 1 227 ? 148.039 152.240 121.601 1.00 48.71  ? 227 ILE   B CD1 1 
ATOM   1514 N N   . PHE   A 1 228 ? 148.153 149.227 126.325 1.00 50.95  ? 228 PHE   B N   1 
ATOM   1515 C CA  . PHE   A 1 228 ? 148.059 147.923 126.971 1.00 50.95  ? 228 PHE   B CA  1 
ATOM   1516 C C   . PHE   A 1 228 ? 147.348 148.009 128.314 1.00 50.95  ? 228 PHE   B C   1 
ATOM   1517 O O   . PHE   A 1 228 ? 146.483 147.181 128.624 1.00 50.95  ? 228 PHE   B O   1 
ATOM   1518 C CB  . PHE   A 1 228 ? 149.458 147.353 127.142 1.00 50.95  ? 228 PHE   B CB  1 
ATOM   1519 C CG  . PHE   A 1 228 ? 149.504 146.073 127.889 1.00 50.95  ? 228 PHE   B CG  1 
ATOM   1520 C CD1 . PHE   A 1 228 ? 148.888 144.953 127.393 1.00 50.95  ? 228 PHE   B CD1 1 
ATOM   1521 C CD2 . PHE   A 1 228 ? 150.178 145.988 129.084 1.00 50.95  ? 228 PHE   B CD2 1 
ATOM   1522 C CE1 . PHE   A 1 228 ? 148.942 143.775 128.075 1.00 50.95  ? 228 PHE   B CE1 1 
ATOM   1523 C CE2 . PHE   A 1 228 ? 150.233 144.814 129.770 1.00 50.95  ? 228 PHE   B CE2 1 
ATOM   1524 C CZ  . PHE   A 1 228 ? 149.611 143.705 129.271 1.00 50.95  ? 228 PHE   B CZ  1 
ATOM   1525 N N   . ASN   A 1 229 ? 147.691 149.008 129.122 1.00 50.92  ? 229 ASN   B N   1 
ATOM   1526 C CA  . ASN   A 1 229 ? 147.064 149.153 130.429 1.00 50.92  ? 229 ASN   B CA  1 
ATOM   1527 C C   . ASN   A 1 229 ? 145.590 149.521 130.309 1.00 50.92  ? 229 ASN   B C   1 
ATOM   1528 O O   . ASN   A 1 229 ? 144.735 148.946 131.005 1.00 50.92  ? 229 ASN   B O   1 
ATOM   1529 C CB  . ASN   A 1 229 ? 147.818 150.190 131.248 1.00 50.92  ? 229 ASN   B CB  1 
ATOM   1530 C CG  . ASN   A 1 229 ? 148.997 149.600 131.965 1.00 50.92  ? 229 ASN   B CG  1 
ATOM   1531 O OD1 . ASN   A 1 229 ? 150.122 150.074 131.830 1.00 50.92  ? 229 ASN   B OD1 1 
ATOM   1532 N ND2 . ASN   A 1 229 ? 148.753 148.546 132.728 1.00 50.92  ? 229 ASN   B ND2 1 
ATOM   1533 N N   . ASP   A 1 230 ? 145.266 150.471 129.432 1.00 50.79  ? 230 ASP   B N   1 
ATOM   1534 C CA  . ASP   A 1 230 ? 143.863 150.794 129.211 1.00 50.79  ? 230 ASP   B CA  1 
ATOM   1535 C C   . ASP   A 1 230 ? 143.093 149.578 128.723 1.00 50.79  ? 230 ASP   B C   1 
ATOM   1536 O O   . ASP   A 1 230 ? 141.941 149.367 129.113 1.00 50.79  ? 230 ASP   B O   1 
ATOM   1537 C CB  . ASP   A 1 230 ? 143.737 151.938 128.213 1.00 50.79  ? 230 ASP   B CB  1 
ATOM   1538 C CG  . ASP   A 1 230 ? 144.388 153.207 128.704 1.00 50.79  ? 230 ASP   B CG  1 
ATOM   1539 O OD1 . ASP   A 1 230 ? 144.669 153.299 129.917 1.00 50.79  ? 230 ASP   B OD1 1 
ATOM   1540 O OD2 . ASP   A 1 230 ? 144.617 154.113 127.877 1.00 50.79  ? 230 ASP   B OD2 1 
ATOM   1541 N N   . CYS   A 1 231 ? 143.707 148.767 127.864 1.00 51.82  ? 231 CYS   B N   1 
ATOM   1542 C CA  . CYS   A 1 231 ? 143.030 147.578 127.366 1.00 51.82  ? 231 CYS   B CA  1 
ATOM   1543 C C   . CYS   A 1 231 ? 142.810 146.564 128.475 1.00 51.82  ? 231 CYS   B C   1 
ATOM   1544 O O   . CYS   A 1 231 ? 141.778 145.890 128.504 1.00 51.82  ? 231 CYS   B O   1 
ATOM   1545 C CB  . CYS   A 1 231 ? 143.822 146.960 126.220 1.00 51.82  ? 231 CYS   B CB  1 
ATOM   1546 S SG  . CYS   A 1 231 ? 143.542 147.769 124.635 1.00 51.82  ? 231 CYS   B SG  1 
ATOM   1547 N N   . LYS   A 1 232 ? 143.774 146.423 129.381 1.00 48.44  ? 232 LYS   B N   1 
ATOM   1548 C CA  . LYS   A 1 232 ? 143.558 145.575 130.547 1.00 48.44  ? 232 LYS   B CA  1 
ATOM   1549 C C   . LYS   A 1 232 ? 142.342 146.043 131.332 1.00 48.44  ? 232 LYS   B C   1 
ATOM   1550 O O   . LYS   A 1 232 ? 141.508 145.229 131.748 1.00 48.44  ? 232 LYS   B O   1 
ATOM   1551 C CB  . LYS   A 1 232 ? 144.798 145.579 131.430 1.00 48.44  ? 232 LYS   B CB  1 
ATOM   1552 C CG  . LYS   A 1 232 ? 145.158 144.254 132.010 1.00 48.44  ? 232 LYS   B CG  1 
ATOM   1553 C CD  . LYS   A 1 232 ? 146.600 144.254 132.433 1.00 48.44  ? 232 LYS   B CD  1 
ATOM   1554 C CE  . LYS   A 1 232 ? 146.829 145.200 133.586 1.00 48.44  ? 232 LYS   B CE  1 
ATOM   1555 N NZ  . LYS   A 1 232 ? 148.233 145.138 134.077 1.00 48.44  ? 232 LYS   B NZ  1 
ATOM   1556 N N   . ASP   A 1 233 ? 142.207 147.356 131.513 1.00 48.36  ? 233 ASP   B N   1 
ATOM   1557 C CA  . ASP   A 1 233 ? 141.025 147.879 132.195 1.00 48.36  ? 233 ASP   B CA  1 
ATOM   1558 C C   . ASP   A 1 233 ? 139.743 147.561 131.426 1.00 48.36  ? 233 ASP   B C   1 
ATOM   1559 O O   . ASP   A 1 233 ? 138.732 147.179 132.023 1.00 48.36  ? 233 ASP   B O   1 
ATOM   1560 C CB  . ASP   A 1 233 ? 141.166 149.383 132.401 1.00 48.36  ? 233 ASP   B CB  1 
ATOM   1561 C CG  . ASP   A 1 233 ? 140.078 149.961 133.286 1.00 48.36  ? 233 ASP   B CG  1 
ATOM   1562 O OD1 . ASP   A 1 233 ? 139.183 149.215 133.727 1.00 48.36  ? 233 ASP   B OD1 1 
ATOM   1563 O OD2 . ASP   A 1 233 ? 140.123 151.179 133.554 1.00 48.36  ? 233 ASP   B OD2 1 
ATOM   1564 N N   . ILE   A 1 234 ? 139.768 147.709 130.104 1.00 46.79  ? 234 ILE   B N   1 
ATOM   1565 C CA  . ILE   A 1 234 ? 138.576 147.464 129.291 1.00 46.79  ? 234 ILE   B CA  1 
ATOM   1566 C C   . ILE   A 1 234 ? 138.149 146.006 129.390 1.00 46.79  ? 234 ILE   B C   1 
ATOM   1567 O O   . ILE   A 1 234 ? 136.961 145.690 129.559 1.00 46.79  ? 234 ILE   B O   1 
ATOM   1568 C CB  . ILE   A 1 234 ? 138.847 147.864 127.833 1.00 46.79  ? 234 ILE   B CB  1 
ATOM   1569 C CG1 . ILE   A 1 234 ? 139.107 149.359 127.735 1.00 46.79  ? 234 ILE   B CG1 1 
ATOM   1570 C CG2 . ILE   A 1 234 ? 137.682 147.490 126.957 1.00 46.79  ? 234 ILE   B CG2 1 
ATOM   1571 C CD1 . ILE   A 1 234 ? 139.195 149.853 126.345 1.00 46.79  ? 234 ILE   B CD1 1 
ATOM   1572 N N   . ILE   A 1 235 ? 139.116 145.092 129.279 1.00 47.71  ? 235 ILE   B N   1 
ATOM   1573 C CA  . ILE   A 1 235 ? 138.820 143.668 129.361 1.00 47.71  ? 235 ILE   B CA  1 
ATOM   1574 C C   . ILE   A 1 235 ? 138.297 143.309 130.741 1.00 47.71  ? 235 ILE   B C   1 
ATOM   1575 O O   . ILE   A 1 235 ? 137.359 142.515 130.875 1.00 47.71  ? 235 ILE   B O   1 
ATOM   1576 C CB  . ILE   A 1 235 ? 140.057 142.837 128.985 1.00 47.71  ? 235 ILE   B CB  1 
ATOM   1577 C CG1 . ILE   A 1 235 ? 140.632 143.304 127.659 1.00 47.71  ? 235 ILE   B CG1 1 
ATOM   1578 C CG2 . ILE   A 1 235 ? 139.720 141.368 128.929 1.00 47.71  ? 235 ILE   B CG2 1 
ATOM   1579 C CD1 . ILE   A 1 235 ? 139.689 143.130 126.506 1.00 47.71  ? 235 ILE   B CD1 1 
ATOM   1580 N N   . LEU   A 1 236 ? 138.896 143.872 131.788 1.00 49.16  ? 236 LEU   B N   1 
ATOM   1581 C CA  . LEU   A 1 236 ? 138.399 143.633 133.137 1.00 49.16  ? 236 LEU   B CA  1 
ATOM   1582 C C   . LEU   A 1 236 ? 136.969 144.119 133.291 1.00 49.16  ? 236 LEU   B C   1 
ATOM   1583 O O   . LEU   A 1 236 ? 136.146 143.458 133.937 1.00 49.16  ? 236 LEU   B O   1 
ATOM   1584 C CB  . LEU   A 1 236 ? 139.316 144.320 134.137 1.00 49.16  ? 236 LEU   B CB  1 
ATOM   1585 C CG  . LEU   A 1 236 ? 139.032 144.284 135.620 1.00 49.16  ? 236 LEU   B CG  1 
ATOM   1586 C CD1 . LEU   A 1 236 ? 140.342 144.252 136.360 1.00 49.16  ? 236 LEU   B CD1 1 
ATOM   1587 C CD2 . LEU   A 1 236 ? 138.258 145.519 136.010 1.00 49.16  ? 236 LEU   B CD2 1 
ATOM   1588 N N   . GLN   A 1 237 ? 136.656 145.277 132.717 1.00 51.37  ? 237 GLN   B N   1 
ATOM   1589 C CA  . GLN   A 1 237 ? 135.297 145.792 132.786 1.00 51.37  ? 237 GLN   B CA  1 
ATOM   1590 C C   . GLN   A 1 237 ? 134.319 144.838 132.121 1.00 51.37  ? 237 GLN   B C   1 
ATOM   1591 O O   . GLN   A 1 237 ? 133.267 144.526 132.683 1.00 51.37  ? 237 GLN   B O   1 
ATOM   1592 C CB  . GLN   A 1 237 ? 135.219 147.168 132.132 1.00 51.37  ? 237 GLN   B CB  1 
ATOM   1593 C CG  . GLN   A 1 237 ? 135.861 148.273 132.929 1.00 51.37  ? 237 GLN   B CG  1 
ATOM   1594 C CD  . GLN   A 1 237 ? 135.001 148.720 134.076 1.00 51.37  ? 237 GLN   B CD  1 
ATOM   1595 O OE1 . GLN   A 1 237 ? 133.792 148.869 133.932 1.00 51.37  ? 237 GLN   B OE1 1 
ATOM   1596 N NE2 . GLN   A 1 237 ? 135.615 148.934 135.228 1.00 51.37  ? 237 GLN   B NE2 1 
ATOM   1597 N N   . MET   A 1 238 ? 134.642 144.364 130.920 1.00 54.14  ? 238 MET   B N   1 
ATOM   1598 C CA  . MET   A 1 238 ? 133.672 143.503 130.254 1.00 54.14  ? 238 MET   B CA  1 
ATOM   1599 C C   . MET   A 1 238 ? 133.606 142.131 130.910 1.00 54.14  ? 238 MET   B C   1 
ATOM   1600 O O   . MET   A 1 238 ? 132.569 141.465 130.839 1.00 54.14  ? 238 MET   B O   1 
ATOM   1601 C CB  . MET   A 1 238 ? 133.965 143.375 128.761 1.00 54.14  ? 238 MET   B CB  1 
ATOM   1602 C CG  . MET   A 1 238 ? 135.256 142.700 128.415 1.00 54.14  ? 238 MET   B CG  1 
ATOM   1603 S SD  . MET   A 1 238 ? 135.523 142.702 126.635 1.00 54.14  ? 238 MET   B SD  1 
ATOM   1604 C CE  . MET   A 1 238 ? 135.934 144.419 126.355 1.00 54.14  ? 238 MET   B CE  1 
ATOM   1605 N N   . ASN   A 1 239 ? 134.679 141.703 131.579 1.00 50.99  ? 239 ASN   B N   1 
ATOM   1606 C CA  . ASN   A 1 239 ? 134.640 140.429 132.288 1.00 50.99  ? 239 ASN   B CA  1 
ATOM   1607 C C   . ASN   A 1 239 ? 133.791 140.516 133.546 1.00 50.99  ? 239 ASN   B C   1 
ATOM   1608 O O   . ASN   A 1 239 ? 133.041 139.583 133.852 1.00 50.99  ? 239 ASN   B O   1 
ATOM   1609 C CB  . ASN   A 1 239 ? 136.048 139.965 132.636 1.00 50.99  ? 239 ASN   B CB  1 
ATOM   1610 C CG  . ASN   A 1 239 ? 136.645 139.095 131.568 1.00 50.99  ? 239 ASN   B CG  1 
ATOM   1611 O OD1 . ASN   A 1 239 ? 135.928 138.484 130.784 1.00 50.99  ? 239 ASN   B OD1 1 
ATOM   1612 N ND2 . ASN   A 1 239 ? 137.963 139.040 131.519 1.00 50.99  ? 239 ASN   B ND2 1 
ATOM   1613 N N   . LEU   A 1 240 ? 133.891 141.609 134.297 1.00 55.14  ? 240 LEU   B N   1 
ATOM   1614 C CA  . LEU   A 1 240 ? 133.027 141.728 135.463 1.00 55.14  ? 240 LEU   B CA  1 
ATOM   1615 C C   . LEU   A 1 240 ? 131.653 142.288 135.126 1.00 55.14  ? 240 LEU   B C   1 
ATOM   1616 O O   . LEU   A 1 240 ? 130.794 142.351 136.009 1.00 55.14  ? 240 LEU   B O   1 
ATOM   1617 C CB  . LEU   A 1 240 ? 133.682 142.569 136.558 1.00 55.14  ? 240 LEU   B CB  1 
ATOM   1618 C CG  . LEU   A 1 240 ? 134.080 144.027 136.396 1.00 55.14  ? 240 LEU   B CG  1 
ATOM   1619 C CD1 . LEU   A 1 240 ? 132.911 144.955 136.626 1.00 55.14  ? 240 LEU   B CD1 1 
ATOM   1620 C CD2 . LEU   A 1 240 ? 135.160 144.326 137.403 1.00 55.14  ? 240 LEU   B CD2 1 
ATOM   1621 N N   . ARG   A 1 241 ? 131.417 142.693 133.886 1.00 56.83  ? 241 ARG   B N   1 
ATOM   1622 C CA  . ARG   A 1 241 ? 130.074 143.013 133.439 1.00 56.83  ? 241 ARG   B CA  1 
ATOM   1623 C C   . ARG   A 1 241 ? 129.399 141.839 132.756 1.00 56.83  ? 241 ARG   B C   1 
ATOM   1624 O O   . ARG   A 1 241 ? 128.175 141.848 132.601 1.00 56.83  ? 241 ARG   B O   1 
ATOM   1625 C CB  . ARG   A 1 241 ? 130.109 144.205 132.476 1.00 56.83  ? 241 ARG   B CB  1 
ATOM   1626 C CG  . ARG   A 1 241 ? 128.949 145.170 132.618 1.00 56.83  ? 241 ARG   B CG  1 
ATOM   1627 C CD  . ARG   A 1 241 ? 129.330 146.538 132.084 1.00 56.83  ? 241 ARG   B CD  1 
ATOM   1628 N NE  . ARG   A 1 241 ? 129.898 146.453 130.742 1.00 56.83  ? 241 ARG   B NE  1 
ATOM   1629 C CZ  . ARG   A 1 241 ? 131.042 147.021 130.376 1.00 56.83  ? 241 ARG   B CZ  1 
ATOM   1630 N NH1 . ARG   A 1 241 ? 131.748 147.720 131.253 1.00 56.83  ? 241 ARG   B NH1 1 
ATOM   1631 N NH2 . ARG   A 1 241 ? 131.479 146.892 129.133 1.00 56.83  ? 241 ARG   B NH2 1 
ATOM   1632 N N   . GLU   A 1 242 ? 130.173 140.845 132.335 1.00 56.48  ? 242 GLU   B N   1 
ATOM   1633 C CA  . GLU   A 1 242 ? 129.638 139.614 131.782 1.00 56.48  ? 242 GLU   B CA  1 
ATOM   1634 C C   . GLU   A 1 242 ? 129.354 138.586 132.866 1.00 56.48  ? 242 GLU   B C   1 
ATOM   1635 O O   . GLU   A 1 242 ? 128.356 137.863 132.788 1.00 56.48  ? 242 GLU   B O   1 
ATOM   1636 C CB  . GLU   A 1 242 ? 130.615 139.041 130.755 1.00 56.48  ? 242 GLU   B CB  1 
ATOM   1637 C CG  . GLU   A 1 242 ? 130.280 137.647 130.273 1.00 56.48  ? 242 GLU   B CG  1 
ATOM   1638 C CD  . GLU   A 1 242 ? 131.162 137.209 129.122 1.00 56.48  ? 242 GLU   B CD  1 
ATOM   1639 O OE1 . GLU   A 1 242 ? 132.321 137.669 129.053 1.00 56.48  ? 242 GLU   B OE1 1 
ATOM   1640 O OE2 . GLU   A 1 242 ? 130.697 136.406 128.286 1.00 56.48  ? 242 GLU   B OE2 1 
ATOM   1641 N N   . TYR   A 1 243 ? 130.206 138.510 133.882 1.00 56.54  ? 243 TYR   B N   1 
ATOM   1642 C CA  . TYR   A 1 243 ? 130.005 137.563 134.976 1.00 56.54  ? 243 TYR   B CA  1 
ATOM   1643 C C   . TYR   A 1 243 ? 129.242 138.205 136.131 1.00 56.54  ? 243 TYR   B C   1 
ATOM   1644 O O   . TYR   A 1 243 ? 129.589 138.054 137.294 1.00 56.54  ? 243 TYR   B O   1 
ATOM   1645 C CB  . TYR   A 1 243 ? 131.355 137.032 135.440 1.00 56.54  ? 243 TYR   B CB  1 
ATOM   1646 C CG  . TYR   A 1 243 ? 132.190 136.400 134.346 1.00 56.54  ? 243 TYR   B CG  1 
ATOM   1647 C CD1 . TYR   A 1 243 ? 133.519 136.086 134.556 1.00 56.54  ? 243 TYR   B CD1 1 
ATOM   1648 C CD2 . TYR   A 1 243 ? 131.640 136.085 133.116 1.00 56.54  ? 243 TYR   B CD2 1 
ATOM   1649 C CE1 . TYR   A 1 243 ? 134.279 135.506 133.556 1.00 56.54  ? 243 TYR   B CE1 1 
ATOM   1650 C CE2 . TYR   A 1 243 ? 132.389 135.512 132.121 1.00 56.54  ? 243 TYR   B CE2 1 
ATOM   1651 C CZ  . TYR   A 1 243 ? 133.702 135.221 132.341 1.00 56.54  ? 243 TYR   B CZ  1 
ATOM   1652 O OH  . TYR   A 1 243 ? 134.432 134.640 131.334 1.00 56.54  ? 243 TYR   B OH  1 
ATOM   1653 N N   . ASN   A 1 244 ? 128.170 138.919 135.798 1.00 65.19  ? 244 ASN   B N   1 
ATOM   1654 C CA  . ASN   A 1 244 ? 127.173 139.386 136.754 1.00 65.19  ? 244 ASN   B CA  1 
ATOM   1655 C C   . ASN   A 1 244 ? 127.734 140.132 137.961 1.00 65.19  ? 244 ASN   B C   1 
ATOM   1656 O O   . ASN   A 1 244 ? 127.013 140.332 138.941 1.00 65.19  ? 244 ASN   B O   1 
ATOM   1657 C CB  . ASN   A 1 244 ? 126.335 138.201 137.243 1.00 65.19  ? 244 ASN   B CB  1 
ATOM   1658 C CG  . ASN   A 1 244 ? 125.273 137.787 136.243 1.00 65.19  ? 244 ASN   B CG  1 
ATOM   1659 O OD1 . ASN   A 1 244 ? 124.606 138.630 135.643 1.00 65.19  ? 244 ASN   B OD1 1 
ATOM   1660 N ND2 . ASN   A 1 244 ? 125.110 136.482 136.059 1.00 65.19  ? 244 ASN   B ND2 1 
ATOM   1661 N N   . LEU   A 1 245 ? 128.996 140.556 137.921 1.00 65.82  ? 245 LEU   B N   1 
ATOM   1662 C CA  . LEU   A 1 245 ? 129.514 141.331 139.043 1.00 65.82  ? 245 LEU   B CA  1 
ATOM   1663 C C   . LEU   A 1 245 ? 128.850 142.695 139.145 1.00 65.82  ? 245 LEU   B C   1 
ATOM   1664 O O   . LEU   A 1 245 ? 129.041 143.386 140.150 1.00 65.82  ? 245 LEU   B O   1 
ATOM   1665 C CB  . LEU   A 1 245 ? 131.026 141.556 138.939 1.00 65.82  ? 245 LEU   B CB  1 
ATOM   1666 C CG  . LEU   A 1 245 ? 132.079 140.514 139.332 1.00 65.82  ? 245 LEU   B CG  1 
ATOM   1667 C CD1 . LEU   A 1 245 ? 132.000 140.106 140.800 1.00 65.82  ? 245 LEU   B CD1 1 
ATOM   1668 C CD2 . LEU   A 1 245 ? 132.085 139.325 138.394 1.00 65.82  ? 245 LEU   B CD2 1 
ATOM   1669 N N   . VAL   A 1 246 ? 128.106 143.103 138.122 1.00 73.49  ? 246 VAL   B N   1 
ATOM   1670 C CA  . VAL   A 1 246 ? 127.438 144.394 138.104 1.00 73.49  ? 246 VAL   B CA  1 
ATOM   1671 C C   . VAL   A 1 246 ? 125.940 144.203 137.900 1.00 73.49  ? 246 VAL   B C   1 
ATOM   1672 O O   . VAL   A 1 246 ? 125.508 143.643 136.892 1.00 73.49  ? 246 VAL   B O   1 
ATOM   1673 C CB  . VAL   A 1 246 ? 128.019 145.300 137.012 1.00 73.49  ? 246 VAL   B CB  1 
ATOM   1674 C CG1 . VAL   A 1 246 ? 127.210 146.585 136.898 1.00 73.49  ? 246 VAL   B CG1 1 
ATOM   1675 C CG2 . VAL   A 1 246 ? 129.472 145.593 137.296 1.00 73.49  ? 246 VAL   B CG2 1 
ATOM   1676 N N   . GLU   B 2 21  ? 122.979 181.319 83.596  1.00 155.59 ? 3   GLU   C N   1 
ATOM   1677 C CA  . GLU   B 2 21  ? 123.688 181.536 84.850  1.00 155.59 ? 3   GLU   C CA  1 
ATOM   1678 C C   . GLU   B 2 21  ? 123.217 180.553 85.913  1.00 155.59 ? 3   GLU   C C   1 
ATOM   1679 O O   . GLU   B 2 21  ? 122.427 179.652 85.631  1.00 155.59 ? 3   GLU   C O   1 
ATOM   1680 C CB  . GLU   B 2 21  ? 123.492 182.973 85.338  1.00 155.59 ? 3   GLU   C CB  1 
ATOM   1681 N N   . LEU   B 2 22  ? 123.717 180.729 87.139  1.00 156.38 ? 4   LEU   C N   1 
ATOM   1682 C CA  . LEU   B 2 22  ? 123.292 179.867 88.236  1.00 156.38 ? 4   LEU   C CA  1 
ATOM   1683 C C   . LEU   B 2 22  ? 121.820 180.063 88.567  1.00 156.38 ? 4   LEU   C C   1 
ATOM   1684 O O   . LEU   B 2 22  ? 121.101 179.083 88.791  1.00 156.38 ? 4   LEU   C O   1 
ATOM   1685 C CB  . LEU   B 2 22  ? 124.153 180.126 89.472  1.00 156.38 ? 4   LEU   C CB  1 
ATOM   1686 N N   . ASP   B 2 23  ? 121.354 181.312 88.599  1.00 156.35 ? 5   ASP   C N   1 
ATOM   1687 C CA  . ASP   B 2 23  ? 119.942 181.567 88.862  1.00 156.35 ? 5   ASP   C CA  1 
ATOM   1688 C C   . ASP   B 2 23  ? 119.063 180.991 87.759  1.00 156.35 ? 5   ASP   C C   1 
ATOM   1689 O O   . ASP   B 2 23  ? 118.005 180.415 88.037  1.00 156.35 ? 5   ASP   C O   1 
ATOM   1690 C CB  . ASP   B 2 23  ? 119.699 183.068 89.015  1.00 156.35 ? 5   ASP   C CB  1 
ATOM   1691 N N   . GLN   B 2 24  ? 119.482 181.141 86.500  1.00 155.31 ? 6   GLN   C N   1 
ATOM   1692 C CA  . GLN   B 2 24  ? 118.692 180.617 85.390  1.00 155.31 ? 6   GLN   C CA  1 
ATOM   1693 C C   . GLN   B 2 24  ? 118.612 179.096 85.436  1.00 155.31 ? 6   GLN   C C   1 
ATOM   1694 O O   . GLN   B 2 24  ? 117.536 178.516 85.247  1.00 155.31 ? 6   GLN   C O   1 
ATOM   1695 C CB  . GLN   B 2 24  ? 119.285 181.084 84.060  1.00 155.31 ? 6   GLN   C CB  1 
ATOM   1696 N N   . LEU   B 2 25  ? 119.742 178.435 85.692  1.00 153.67 ? 7   LEU   C N   1 
ATOM   1697 C CA  . LEU   B 2 25  ? 119.739 176.980 85.801  1.00 153.67 ? 7   LEU   C CA  1 
ATOM   1698 C C   . LEU   B 2 25  ? 118.902 176.520 86.987  1.00 153.67 ? 7   LEU   C C   1 
ATOM   1699 O O   . LEU   B 2 25  ? 118.183 175.518 86.896  1.00 153.67 ? 7   LEU   C O   1 
ATOM   1700 C CB  . LEU   B 2 25  ? 121.171 176.460 85.919  1.00 153.67 ? 7   LEU   C CB  1 
ATOM   1701 N N   . ARG   B 2 26  ? 118.986 177.236 88.111  1.00 153.03 ? 8   ARG   C N   1 
ATOM   1702 C CA  . ARG   B 2 26  ? 118.182 176.880 89.275  1.00 153.03 ? 8   ARG   C CA  1 
ATOM   1703 C C   . ARG   B 2 26  ? 116.694 177.014 88.977  1.00 153.03 ? 8   ARG   C C   1 
ATOM   1704 O O   . ARG   B 2 26  ? 115.897 176.147 89.353  1.00 153.03 ? 8   ARG   C O   1 
ATOM   1705 C CB  . ARG   B 2 26  ? 118.572 177.752 90.467  1.00 153.03 ? 8   ARG   C CB  1 
ATOM   1706 N N   . GLN   B 2 27  ? 116.302 178.097 88.300  1.00 150.16 ? 9   GLN   C N   1 
ATOM   1707 C CA  . GLN   B 2 27  ? 114.902 178.275 87.935  1.00 150.16 ? 9   GLN   C CA  1 
ATOM   1708 C C   . GLN   B 2 27  ? 114.439 177.183 86.981  1.00 150.16 ? 9   GLN   C C   1 
ATOM   1709 O O   . GLN   B 2 27  ? 113.326 176.660 87.116  1.00 150.16 ? 9   GLN   C O   1 
ATOM   1710 C CB  . GLN   B 2 27  ? 114.694 179.656 87.314  1.00 150.16 ? 9   GLN   C CB  1 
ATOM   1711 N N   . GLU   B 2 28  ? 115.280 176.825 86.007  1.00 148.28 ? 10  GLU   C N   1 
ATOM   1712 C CA  . GLU   B 2 28  ? 114.916 175.763 85.075  1.00 148.28 ? 10  GLU   C CA  1 
ATOM   1713 C C   . GLU   B 2 28  ? 114.744 174.432 85.797  1.00 148.28 ? 10  GLU   C C   1 
ATOM   1714 O O   . GLU   B 2 28  ? 113.788 173.690 85.533  1.00 148.28 ? 10  GLU   C O   1 
ATOM   1715 C CB  . GLU   B 2 28  ? 115.972 175.646 83.975  1.00 148.28 ? 10  GLU   C CB  1 
ATOM   1716 N N   . ALA   B 2 29  ? 115.658 174.115 86.717  1.00 146.51 ? 11  ALA   C N   1 
ATOM   1717 C CA  . ALA   B 2 29  ? 115.555 172.868 87.466  1.00 146.51 ? 11  ALA   C CA  1 
ATOM   1718 C C   . ALA   B 2 29  ? 114.308 172.850 88.341  1.00 146.51 ? 11  ALA   C C   1 
ATOM   1719 O O   . ALA   B 2 29  ? 113.627 171.823 88.439  1.00 146.51 ? 11  ALA   C O   1 
ATOM   1720 C CB  . ALA   B 2 29  ? 116.810 172.659 88.313  1.00 146.51 ? 11  ALA   C CB  1 
ATOM   1721 N N   . GLU   B 2 30  ? 113.998 173.975 88.991  1.00 145.42 ? 12  GLU   C N   1 
ATOM   1722 C CA  . GLU   B 2 30  ? 112.798 174.040 89.819  1.00 145.42 ? 12  GLU   C CA  1 
ATOM   1723 C C   . GLU   B 2 30  ? 111.540 173.867 88.979  1.00 145.42 ? 12  GLU   C C   1 
ATOM   1724 O O   . GLU   B 2 30  ? 110.606 173.161 89.381  1.00 145.42 ? 12  GLU   C O   1 
ATOM   1725 C CB  . GLU   B 2 30  ? 112.757 175.364 90.582  1.00 145.42 ? 12  GLU   C CB  1 
ATOM   1726 N N   . GLN   B 2 31  ? 111.501 174.499 87.803  1.00 142.28 ? 13  GLN   C N   1 
ATOM   1727 C CA  . GLN   B 2 31  ? 110.352 174.346 86.918  1.00 142.28 ? 13  GLN   C CA  1 
ATOM   1728 C C   . GLN   B 2 31  ? 110.200 172.903 86.458  1.00 142.28 ? 13  GLN   C C   1 
ATOM   1729 O O   . GLN   B 2 31  ? 109.085 172.370 86.421  1.00 142.28 ? 13  GLN   C O   1 
ATOM   1730 C CB  . GLN   B 2 31  ? 110.487 175.282 85.718  1.00 142.28 ? 13  GLN   C CB  1 
ATOM   1731 N N   . LEU   B 2 32  ? 111.311 172.251 86.105  1.00 136.69 ? 14  LEU   C N   1 
ATOM   1732 C CA  . LEU   B 2 32  ? 111.240 170.859 85.671  1.00 136.69 ? 14  LEU   C CA  1 
ATOM   1733 C C   . LEU   B 2 32  ? 110.781 169.948 86.804  1.00 136.69 ? 14  LEU   C C   1 
ATOM   1734 O O   . LEU   B 2 32  ? 109.975 169.033 86.589  1.00 136.69 ? 14  LEU   C O   1 
ATOM   1735 C CB  . LEU   B 2 32  ? 112.595 170.409 85.127  1.00 136.69 ? 14  LEU   C CB  1 
ATOM   1736 C CG  . LEU   B 2 32  ? 112.722 170.445 83.601  1.00 136.69 ? 14  LEU   C CG  1 
ATOM   1737 C CD1 . LEU   B 2 32  ? 112.617 171.867 83.081  1.00 136.69 ? 14  LEU   C CD1 1 
ATOM   1738 C CD2 . LEU   B 2 32  ? 114.023 169.810 83.148  1.00 136.69 ? 14  LEU   C CD2 1 
ATOM   1739 N N   . LYS   B 2 33  ? 111.280 170.183 88.020  1.00 135.52 ? 15  LYS   C N   1 
ATOM   1740 C CA  . LYS   B 2 33  ? 110.854 169.380 89.161  1.00 135.52 ? 15  LYS   C CA  1 
ATOM   1741 C C   . LYS   B 2 33  ? 109.367 169.563 89.437  1.00 135.52 ? 15  LYS   C C   1 
ATOM   1742 O O   . LYS   B 2 33  ? 108.652 168.588 89.705  1.00 135.52 ? 15  LYS   C O   1 
ATOM   1743 C CB  . LYS   B 2 33  ? 111.679 169.743 90.395  1.00 135.52 ? 15  LYS   C CB  1 
ATOM   1744 N N   . ASN   B 2 34  ? 108.881 170.806 89.373  1.00 132.62 ? 16  ASN   C N   1 
ATOM   1745 C CA  . ASN   B 2 34  ? 107.457 171.053 89.570  1.00 132.62 ? 16  ASN   C CA  1 
ATOM   1746 C C   . ASN   B 2 34  ? 106.628 170.387 88.481  1.00 132.62 ? 16  ASN   C C   1 
ATOM   1747 O O   . ASN   B 2 34  ? 105.555 169.838 88.755  1.00 132.62 ? 16  ASN   C O   1 
ATOM   1748 C CB  . ASN   B 2 34  ? 107.185 172.557 89.610  1.00 132.62 ? 16  ASN   C CB  1 
ATOM   1749 N N   . GLN   B 2 35  ? 107.111 170.425 87.237  1.00 128.77 ? 17  GLN   C N   1 
ATOM   1750 C CA  . GLN   B 2 35  ? 106.392 169.778 86.145  1.00 128.77 ? 17  GLN   C CA  1 
ATOM   1751 C C   . GLN   B 2 35  ? 106.299 168.273 86.363  1.00 128.77 ? 17  GLN   C C   1 
ATOM   1752 O O   . GLN   B 2 35  ? 105.242 167.670 86.144  1.00 128.77 ? 17  GLN   C O   1 
ATOM   1753 C CB  . GLN   B 2 35  ? 107.077 170.090 84.814  1.00 128.77 ? 17  GLN   C CB  1 
ATOM   1754 C CG  . GLN   B 2 35  ? 106.566 169.270 83.643  1.00 128.77 ? 17  GLN   C CG  1 
ATOM   1755 C CD  . GLN   B 2 35  ? 107.478 168.111 83.304  1.00 128.77 ? 17  GLN   C CD  1 
ATOM   1756 O OE1 . GLN   B 2 35  ? 108.669 168.134 83.611  1.00 128.77 ? 17  GLN   C OE1 1 
ATOM   1757 N NE2 . GLN   B 2 35  ? 106.922 167.087 82.670  1.00 128.77 ? 17  GLN   C NE2 1 
ATOM   1758 N N   . ILE   B 2 36  ? 107.395 167.650 86.796  1.00 121.52 ? 18  ILE   C N   1 
ATOM   1759 C CA  . ILE   B 2 36  ? 107.377 166.208 87.018  1.00 121.52 ? 18  ILE   C CA  1 
ATOM   1760 C C   . ILE   B 2 36  ? 106.471 165.858 88.193  1.00 121.52 ? 18  ILE   C C   1 
ATOM   1761 O O   . ILE   B 2 36  ? 105.751 164.850 88.161  1.00 121.52 ? 18  ILE   C O   1 
ATOM   1762 C CB  . ILE   B 2 36  ? 108.806 165.677 87.215  1.00 121.52 ? 18  ILE   C CB  1 
ATOM   1763 C CG1 . ILE   B 2 36  ? 109.640 165.927 85.964  1.00 121.52 ? 18  ILE   C CG1 1 
ATOM   1764 C CG2 . ILE   B 2 36  ? 108.786 164.201 87.505  1.00 121.52 ? 18  ILE   C CG2 1 
ATOM   1765 C CD1 . ILE   B 2 36  ? 111.004 165.293 86.014  1.00 121.52 ? 18  ILE   C CD1 1 
ATOM   1766 N N   . ARG   B 2 37  ? 106.488 166.677 89.246  1.00 120.62 ? 19  ARG   C N   1 
ATOM   1767 C CA  . ARG   B 2 37  ? 105.582 166.448 90.366  1.00 120.62 ? 19  ARG   C CA  1 
ATOM   1768 C C   . ARG   B 2 37  ? 104.128 166.547 89.923  1.00 120.62 ? 19  ARG   C C   1 
ATOM   1769 O O   . ARG   B 2 37  ? 103.290 165.731 90.328  1.00 120.62 ? 19  ARG   C O   1 
ATOM   1770 C CB  . ARG   B 2 37  ? 105.869 167.442 91.489  1.00 120.62 ? 19  ARG   C CB  1 
ATOM   1771 N N   . ASP   B 2 38  ? 103.811 167.539 89.088  1.00 118.21 ? 20  ASP   C N   1 
ATOM   1772 C CA  . ASP   B 2 38  ? 102.452 167.670 88.574  1.00 118.21 ? 20  ASP   C CA  1 
ATOM   1773 C C   . ASP   B 2 38  ? 102.069 166.470 87.720  1.00 118.21 ? 20  ASP   C C   1 
ATOM   1774 O O   . ASP   B 2 38  ? 100.935 165.983 87.795  1.00 118.21 ? 20  ASP   C O   1 
ATOM   1775 C CB  . ASP   B 2 38  ? 102.317 168.965 87.773  1.00 118.21 ? 20  ASP   C CB  1 
ATOM   1776 N N   . ALA   B 2 39  ? 102.999 165.984 86.894  1.00 113.59 ? 21  ALA   C N   1 
ATOM   1777 C CA  . ALA   B 2 39  ? 102.715 164.816 86.065  1.00 113.59 ? 21  ALA   C CA  1 
ATOM   1778 C C   . ALA   B 2 39  ? 102.424 163.590 86.920  1.00 113.59 ? 21  ALA   C C   1 
ATOM   1779 O O   . ALA   B 2 39  ? 101.491 162.833 86.633  1.00 113.59 ? 21  ALA   C O   1 
ATOM   1780 C CB  . ALA   B 2 39  ? 103.883 164.543 85.119  1.00 113.59 ? 21  ALA   C CB  1 
ATOM   1781 N N   . ARG   B 2 40  ? 103.215 163.376 87.972  1.00 105.01 ? 22  ARG   C N   1 
ATOM   1782 C CA  . ARG   B 2 40  ? 102.959 162.244 88.857  1.00 105.01 ? 22  ARG   C CA  1 
ATOM   1783 C C   . ARG   B 2 40  ? 101.626 162.400 89.574  1.00 105.01 ? 22  ARG   C C   1 
ATOM   1784 O O   . ARG   B 2 40  ? 100.880 161.426 89.731  1.00 105.01 ? 22  ARG   C O   1 
ATOM   1785 C CB  . ARG   B 2 40  ? 104.093 162.091 89.866  1.00 105.01 ? 22  ARG   C CB  1 
ATOM   1786 C CG  . ARG   B 2 40  ? 105.330 161.415 89.314  1.00 105.01 ? 22  ARG   C CG  1 
ATOM   1787 C CD  . ARG   B 2 40  ? 106.576 161.912 90.025  1.00 105.01 ? 22  ARG   C CD  1 
ATOM   1788 N NE  . ARG   B 2 40  ? 107.780 161.713 89.226  1.00 105.01 ? 22  ARG   C NE  1 
ATOM   1789 C CZ  . ARG   B 2 40  ? 108.904 161.176 89.686  1.00 105.01 ? 22  ARG   C CZ  1 
ATOM   1790 N NH1 . ARG   B 2 40  ? 108.984 160.780 90.948  1.00 105.01 ? 22  ARG   C NH1 1 
ATOM   1791 N NH2 . ARG   B 2 40  ? 109.949 161.037 88.883  1.00 105.01 ? 22  ARG   C NH2 1 
ATOM   1792 N N   . LYS   B 2 41  ? 101.308 163.617 90.020  1.00 111.29 ? 23  LYS   C N   1 
ATOM   1793 C CA  . LYS   B 2 41  ? 100.029 163.846 90.684  1.00 111.29 ? 23  LYS   C CA  1 
ATOM   1794 C C   . LYS   B 2 41  ? 98.863  163.743 89.709  1.00 111.29 ? 23  LYS   C C   1 
ATOM   1795 O O   . LYS   B 2 41  ? 97.749  163.393 90.113  1.00 111.29 ? 23  LYS   C O   1 
ATOM   1796 C CB  . LYS   B 2 41  ? 100.030 165.211 91.371  1.00 111.29 ? 23  LYS   C CB  1 
ATOM   1797 N N   . ALA   B 2 42  ? 99.097  164.040 88.430  1.00 113.07 ? 24  ALA   C N   1 
ATOM   1798 C CA  . ALA   B 2 42  ? 98.033  163.927 87.439  1.00 113.07 ? 24  ALA   C CA  1 
ATOM   1799 C C   . ALA   B 2 42  ? 97.618  162.478 87.219  1.00 113.07 ? 24  ALA   C C   1 
ATOM   1800 O O   . ALA   B 2 42  ? 96.471  162.215 86.839  1.00 113.07 ? 24  ALA   C O   1 
ATOM   1801 C CB  . ALA   B 2 42  ? 98.472  164.559 86.119  1.00 113.07 ? 24  ALA   C CB  1 
ATOM   1802 N N   . CYS   B 2 43  ? 98.524  161.532 87.449  1.00 107.31 ? 25  CYS   C N   1 
ATOM   1803 C CA  . CYS   B 2 43  ? 98.226  160.117 87.285  1.00 107.31 ? 25  CYS   C CA  1 
ATOM   1804 C C   . CYS   B 2 43  ? 97.801  159.442 88.582  1.00 107.31 ? 25  CYS   C C   1 
ATOM   1805 O O   . CYS   B 2 43  ? 97.583  158.227 88.588  1.00 107.31 ? 25  CYS   C O   1 
ATOM   1806 C CB  . CYS   B 2 43  ? 99.440  159.387 86.702  1.00 107.31 ? 25  CYS   C CB  1 
ATOM   1807 S SG  . CYS   B 2 43  ? 99.891  159.906 85.033  1.00 107.31 ? 25  CYS   C SG  1 
ATOM   1808 N N   . ALA   B 2 44  ? 97.680  160.189 89.677  1.00 106.70 ? 26  ALA   C N   1 
ATOM   1809 C CA  . ALA   B 2 44  ? 97.297  159.612 90.966  1.00 106.70 ? 26  ALA   C CA  1 
ATOM   1810 C C   . ALA   B 2 44  ? 95.774  159.571 91.052  1.00 106.70 ? 26  ALA   C C   1 
ATOM   1811 O O   . ALA   B 2 44  ? 95.123  160.434 91.645  1.00 106.70 ? 26  ALA   C O   1 
ATOM   1812 C CB  . ALA   B 2 44  ? 97.909  160.406 92.112  1.00 106.70 ? 26  ALA   C CB  1 
ATOM   1813 N N   . ASP   B 2 45  ? 95.197  158.536 90.439  1.00 103.70 ? 27  ASP   C N   1 
ATOM   1814 C CA  . ASP   B 2 45  ? 93.750  158.345 90.429  1.00 103.70 ? 27  ASP   C CA  1 
ATOM   1815 C C   . ASP   B 2 45  ? 93.300  157.341 91.485  1.00 103.70 ? 27  ASP   C C   1 
ATOM   1816 O O   . ASP   B 2 45  ? 92.451  157.656 92.324  1.00 103.70 ? 27  ASP   C O   1 
ATOM   1817 C CB  . ASP   B 2 45  ? 93.284  157.907 89.031  1.00 103.70 ? 27  ASP   C CB  1 
ATOM   1818 C CG  . ASP   B 2 45  ? 94.160  156.821 88.434  1.00 103.70 ? 27  ASP   C CG  1 
ATOM   1819 O OD1 . ASP   B 2 45  ? 94.834  156.105 89.202  1.00 103.70 ? 27  ASP   C OD1 1 
ATOM   1820 O OD2 . ASP   B 2 45  ? 94.173  156.685 87.194  1.00 103.70 ? 27  ASP   C OD2 1 
ATOM   1821 N N   . ALA   B 2 46  ? 93.855  156.131 91.459  1.00 98.24  ? 28  ALA   C N   1 
ATOM   1822 C CA  . ALA   B 2 46  ? 93.511  155.091 92.416  1.00 98.24  ? 28  ALA   C CA  1 
ATOM   1823 C C   . ALA   B 2 46  ? 94.780  154.460 92.967  1.00 98.24  ? 28  ALA   C C   1 
ATOM   1824 O O   . ALA   B 2 46  ? 95.705  154.145 92.212  1.00 98.24  ? 28  ALA   C O   1 
ATOM   1825 C CB  . ALA   B 2 46  ? 92.626  154.015 91.778  1.00 98.24  ? 28  ALA   C CB  1 
ATOM   1826 N N   . THR   B 2 47  ? 94.819  154.276 94.281  1.00 90.00  ? 29  THR   C N   1 
ATOM   1827 C CA  . THR   B 2 47  ? 95.960  153.670 94.941  1.00 90.00  ? 29  THR   C CA  1 
ATOM   1828 C C   . THR   B 2 47  ? 95.775  152.162 95.039  1.00 90.00  ? 29  THR   C C   1 
ATOM   1829 O O   . THR   B 2 47  ? 94.692  151.625 94.802  1.00 90.00  ? 29  THR   C O   1 
ATOM   1830 C CB  . THR   B 2 47  ? 96.163  154.275 96.331  1.00 90.00  ? 29  THR   C CB  1 
ATOM   1831 O OG1 . THR   B 2 47  ? 95.190  153.737 97.236  1.00 90.00  ? 29  THR   C OG1 1 
ATOM   1832 C CG2 . THR   B 2 47  ? 96.017  155.788 96.279  1.00 90.00  ? 29  THR   C CG2 1 
ATOM   1833 N N   . LEU   B 2 48  ? 96.859  151.472 95.398  1.00 81.92  ? 30  LEU   C N   1 
ATOM   1834 C CA  . LEU   B 2 48  ? 96.821  150.015 95.442  1.00 81.92  ? 30  LEU   C CA  1 
ATOM   1835 C C   . LEU   B 2 48  ? 95.885  149.510 96.529  1.00 81.92  ? 30  LEU   C C   1 
ATOM   1836 O O   . LEU   B 2 48  ? 95.260  148.456 96.364  1.00 81.92  ? 30  LEU   C O   1 
ATOM   1837 C CB  . LEU   B 2 48  ? 98.229  149.458 95.649  1.00 81.92  ? 30  LEU   C CB  1 
ATOM   1838 C CG  . LEU   B 2 48  ? 98.426  147.950 95.508  1.00 81.92  ? 30  LEU   C CG  1 
ATOM   1839 C CD1 . LEU   B 2 48  ? 97.963  147.481 94.154  1.00 81.92  ? 30  LEU   C CD1 1 
ATOM   1840 C CD2 . LEU   B 2 48  ? 99.879  147.589 95.721  1.00 81.92  ? 30  LEU   C CD2 1 
ATOM   1841 N N   . SER   B 2 49  ? 95.770  150.242 97.637  1.00 85.52  ? 31  SER   C N   1 
ATOM   1842 C CA  . SER   B 2 49  ? 94.852  149.830 98.693  1.00 85.52  ? 31  SER   C CA  1 
ATOM   1843 C C   . SER   B 2 49  ? 93.406  149.885 98.217  1.00 85.52  ? 31  SER   C C   1 
ATOM   1844 O O   . SER   B 2 49  ? 92.626  148.960 98.479  1.00 85.52  ? 31  SER   C O   1 
ATOM   1845 C CB  . SER   B 2 49  ? 95.048  150.707 99.929  1.00 85.52  ? 31  SER   C CB  1 
ATOM   1846 O OG  . SER   B 2 49  ? 94.453  150.119 101.072 1.00 85.52  ? 31  SER   C OG  1 
ATOM   1847 N N   . GLN   B 2 50  ? 93.043  150.948 97.492  1.00 89.42  ? 32  GLN   C N   1 
ATOM   1848 C CA  . GLN   B 2 50  ? 91.665  151.120 97.040  1.00 89.42  ? 32  GLN   C CA  1 
ATOM   1849 C C   . GLN   B 2 50  ? 91.197  149.933 96.211  1.00 89.42  ? 32  GLN   C C   1 
ATOM   1850 O O   . GLN   B 2 50  ? 90.044  149.500 96.326  1.00 89.42  ? 32  GLN   C O   1 
ATOM   1851 C CB  . GLN   B 2 50  ? 91.540  152.410 96.231  1.00 89.42  ? 32  GLN   C CB  1 
ATOM   1852 C CG  . GLN   B 2 50  ? 91.214  153.633 97.060  1.00 89.42  ? 32  GLN   C CG  1 
ATOM   1853 C CD  . GLN   B 2 50  ? 91.321  154.914 96.261  1.00 89.42  ? 32  GLN   C CD  1 
ATOM   1854 O OE1 . GLN   B 2 50  ? 91.909  154.935 95.181  1.00 89.42  ? 32  GLN   C OE1 1 
ATOM   1855 N NE2 . GLN   B 2 50  ? 90.753  155.992 96.790  1.00 89.42  ? 32  GLN   C NE2 1 
ATOM   1856 N N   . ILE   B 2 51  ? 92.076  149.391 95.369  1.00 85.06  ? 33  ILE   C N   1 
ATOM   1857 C CA  . ILE   B 2 51  ? 91.695  148.260 94.535  1.00 85.06  ? 33  ILE   C CA  1 
ATOM   1858 C C   . ILE   B 2 51  ? 91.814  146.960 95.310  1.00 85.06  ? 33  ILE   C C   1 
ATOM   1859 O O   . ILE   B 2 51  ? 90.856  146.184 95.397  1.00 85.06  ? 33  ILE   C O   1 
ATOM   1860 C CB  . ILE   B 2 51  ? 92.547  148.228 93.258  1.00 85.06  ? 33  ILE   C CB  1 
ATOM   1861 C CG1 . ILE   B 2 51  ? 92.298  149.479 92.421  1.00 85.06  ? 33  ILE   C CG1 1 
ATOM   1862 C CG2 . ILE   B 2 51  ? 92.231  146.993 92.458  1.00 85.06  ? 33  ILE   C CG2 1 
ATOM   1863 C CD1 . ILE   B 2 51  ? 93.280  149.653 91.288  1.00 85.06  ? 33  ILE   C CD1 1 
ATOM   1864 N N   . THR   B 2 52  ? 92.982  146.705 95.894  1.00 82.14  ? 34  THR   C N   1 
ATOM   1865 C CA  . THR   B 2 52  ? 93.221  145.433 96.560  1.00 82.14  ? 34  THR   C CA  1 
ATOM   1866 C C   . THR   B 2 52  ? 92.422  145.265 97.842  1.00 82.14  ? 34  THR   C C   1 
ATOM   1867 O O   . THR   B 2 52  ? 92.577  144.231 98.502  1.00 82.14  ? 34  THR   C O   1 
ATOM   1868 C CB  . THR   B 2 52  ? 94.708  145.269 96.863  1.00 82.14  ? 34  THR   C CB  1 
ATOM   1869 O OG1 . THR   B 2 52  ? 95.167  146.386 97.634  1.00 82.14  ? 34  THR   C OG1 1 
ATOM   1870 C CG2 . THR   B 2 52  ? 95.503  145.192 95.573  1.00 82.14  ? 34  THR   C CG2 1 
ATOM   1871 N N   . ASN   B 2 53  ? 91.592  146.241 98.222  1.00 83.93  ? 35  ASN   C N   1 
ATOM   1872 C CA  . ASN   B 2 53  ? 90.670  146.020 99.331  1.00 83.93  ? 35  ASN   C CA  1 
ATOM   1873 C C   . ASN   B 2 53  ? 89.789  144.799 99.090  1.00 83.93  ? 35  ASN   C C   1 
ATOM   1874 O O   . ASN   B 2 53  ? 89.419  144.103 100.042 1.00 83.93  ? 35  ASN   C O   1 
ATOM   1875 C CB  . ASN   B 2 53  ? 89.811  147.267 99.549  1.00 83.93  ? 35  ASN   C CB  1 
ATOM   1876 C CG  . ASN   B 2 53  ? 89.160  147.296 100.918 1.00 83.93  ? 35  ASN   C CG  1 
ATOM   1877 O OD1 . ASN   B 2 53  ? 89.384  146.412 101.745 1.00 83.93  ? 35  ASN   C OD1 1 
ATOM   1878 N ND2 . ASN   B 2 53  ? 88.349  148.318 101.165 1.00 83.93  ? 35  ASN   C ND2 1 
ATOM   1879 N N   . ASN   B 2 54  ? 89.444  144.528 97.836  1.00 83.53  ? 36  ASN   C N   1 
ATOM   1880 C CA  . ASN   B 2 54  ? 88.612  143.381 97.482  1.00 83.53  ? 36  ASN   C CA  1 
ATOM   1881 C C   . ASN   B 2 54  ? 89.468  142.219 96.983  1.00 83.53  ? 36  ASN   C C   1 
ATOM   1882 O O   . ASN   B 2 54  ? 89.369  141.780 95.839  1.00 83.53  ? 36  ASN   C O   1 
ATOM   1883 C CB  . ASN   B 2 54  ? 87.574  143.790 96.442  1.00 83.53  ? 36  ASN   C CB  1 
ATOM   1884 C CG  . ASN   B 2 54  ? 86.673  144.909 96.928  1.00 83.53  ? 36  ASN   C CG  1 
ATOM   1885 O OD1 . ASN   B 2 54  ? 86.434  145.052 98.127  1.00 83.53  ? 36  ASN   C OD1 1 
ATOM   1886 N ND2 . ASN   B 2 54  ? 86.168  145.709 95.996  1.00 83.53  ? 36  ASN   C ND2 1 
ATOM   1887 N N   . ILE   B 2 55  ? 90.322  141.719 97.871  1.00 80.54  ? 37  ILE   C N   1 
ATOM   1888 C CA  . ILE   B 2 55  ? 91.087  140.498 97.644  1.00 80.54  ? 37  ILE   C CA  1 
ATOM   1889 C C   . ILE   B 2 55  ? 91.074  139.696 98.935  1.00 80.54  ? 37  ILE   C C   1 
ATOM   1890 O O   . ILE   B 2 55  ? 91.141  140.264 100.030 1.00 80.54  ? 37  ILE   C O   1 
ATOM   1891 C CB  . ILE   B 2 55  ? 92.539  140.782 97.206  1.00 80.54  ? 37  ILE   C CB  1 
ATOM   1892 C CG1 . ILE   B 2 55  ? 92.588  141.577 95.908  1.00 80.54  ? 37  ILE   C CG1 1 
ATOM   1893 C CG2 . ILE   B 2 55  ? 93.316  139.488 97.021  1.00 80.54  ? 37  ILE   C CG2 1 
ATOM   1894 C CD1 . ILE   B 2 55  ? 94.000  141.895 95.487  1.00 80.54  ? 37  ILE   C CD1 1 
ATOM   1895 N N   . ASP   B 2 56  ? 90.982  138.384 98.810  1.00 80.32  ? 38  ASP   C N   1 
ATOM   1896 C CA  . ASP   B 2 56  ? 90.979  137.534 99.987  1.00 80.32  ? 38  ASP   C CA  1 
ATOM   1897 C C   . ASP   B 2 56  ? 92.334  137.608 100.679 1.00 80.32  ? 38  ASP   C C   1 
ATOM   1898 O O   . ASP   B 2 56  ? 93.369  137.461 100.021 1.00 80.32  ? 38  ASP   C O   1 
ATOM   1899 C CB  . ASP   B 2 56  ? 90.658  136.091 99.604  1.00 80.32  ? 38  ASP   C CB  1 
ATOM   1900 N N   . PRO   B 2 57  ? 92.373  137.841 101.987 1.00 82.44  ? 39  PRO   C N   1 
ATOM   1901 C CA  . PRO   B 2 57  ? 93.657  137.879 102.690 1.00 82.44  ? 39  PRO   C CA  1 
ATOM   1902 C C   . PRO   B 2 57  ? 94.327  136.515 102.708 1.00 82.44  ? 39  PRO   C C   1 
ATOM   1903 O O   . PRO   B 2 57  ? 93.673  135.471 102.646 1.00 82.44  ? 39  PRO   C O   1 
ATOM   1904 C CB  . PRO   B 2 57  ? 93.275  138.328 104.104 1.00 82.44  ? 39  PRO   C CB  1 
ATOM   1905 C CG  . PRO   B 2 57  ? 91.842  137.956 104.243 1.00 82.44  ? 39  PRO   C CG  1 
ATOM   1906 C CD  . PRO   B 2 57  ? 91.242  138.127 102.883 1.00 82.44  ? 39  PRO   C CD  1 
ATOM   1907 N N   . VAL   B 2 58  ? 95.659  136.540 102.785 1.00 78.47  ? 40  VAL   C N   1 
ATOM   1908 C CA  . VAL   B 2 58  ? 96.425  135.300 102.846 1.00 78.47  ? 40  VAL   C CA  1 
ATOM   1909 C C   . VAL   B 2 58  ? 96.075  134.522 104.106 1.00 78.47  ? 40  VAL   C C   1 
ATOM   1910 O O   . VAL   B 2 58  ? 95.875  133.301 104.067 1.00 78.47  ? 40  VAL   C O   1 
ATOM   1911 C CB  . VAL   B 2 58  ? 97.931  135.603 102.773 1.00 78.47  ? 40  VAL   C CB  1 
ATOM   1912 C CG1 . VAL   B 2 58  ? 98.735  134.341 103.002 1.00 78.47  ? 40  VAL   C CG1 1 
ATOM   1913 C CG2 . VAL   B 2 58  ? 98.276  136.223 101.440 1.00 78.47  ? 40  VAL   C CG2 1 
ATOM   1914 N N   . GLY   B 2 59  ? 95.990  135.213 105.238 1.00 81.07  ? 41  GLY   C N   1 
ATOM   1915 C CA  . GLY   B 2 59  ? 95.727  134.565 106.506 1.00 81.07  ? 41  GLY   C CA  1 
ATOM   1916 C C   . GLY   B 2 59  ? 96.854  134.775 107.493 1.00 81.07  ? 41  GLY   C C   1 
ATOM   1917 O O   . GLY   B 2 59  ? 97.136  135.909 107.891 1.00 81.07  ? 41  GLY   C O   1 
ATOM   1918 N N   . ARG   B 2 60  ? 97.509  133.690 107.894 1.00 75.39  ? 42  ARG   C N   1 
ATOM   1919 C CA  . ARG   B 2 60  ? 98.646  133.760 108.802 1.00 75.39  ? 42  ARG   C CA  1 
ATOM   1920 C C   . ARG   B 2 60  ? 99.717  132.807 108.302 1.00 75.39  ? 42  ARG   C C   1 
ATOM   1921 O O   . ARG   B 2 60  ? 99.529  131.587 108.340 1.00 75.39  ? 42  ARG   C O   1 
ATOM   1922 C CB  . ARG   B 2 60  ? 98.236  133.408 110.235 1.00 75.39  ? 42  ARG   C CB  1 
ATOM   1923 N N   . ILE   B 2 61  ? 100.834 133.356 107.834 1.00 71.74  ? 43  ILE   C N   1 
ATOM   1924 C CA  . ILE   B 2 61  ? 101.944 132.552 107.340 1.00 71.74  ? 43  ILE   C CA  1 
ATOM   1925 C C   . ILE   B 2 61  ? 102.812 132.200 108.542 1.00 71.74  ? 43  ILE   C C   1 
ATOM   1926 O O   . ILE   B 2 61  ? 103.551 133.036 109.061 1.00 71.74  ? 43  ILE   C O   1 
ATOM   1927 C CB  . ILE   B 2 61  ? 102.741 133.277 106.258 1.00 71.74  ? 43  ILE   C CB  1 
ATOM   1928 C CG1 . ILE   B 2 61  ? 101.868 133.511 105.027 1.00 71.74  ? 43  ILE   C CG1 1 
ATOM   1929 C CG2 . ILE   B 2 61  ? 103.964 132.471 105.879 1.00 71.74  ? 43  ILE   C CG2 1 
ATOM   1930 C CD1 . ILE   B 2 61  ? 101.392 132.233 104.375 1.00 71.74  ? 43  ILE   C CD1 1 
ATOM   1931 N N   . GLN   B 2 62  ? 102.713 130.954 108.987 1.00 69.54  ? 44  GLN   C N   1 
ATOM   1932 C CA  . GLN   B 2 62  ? 103.530 130.430 110.071 1.00 69.54  ? 44  GLN   C CA  1 
ATOM   1933 C C   . GLN   B 2 62  ? 104.517 129.442 109.470 1.00 69.54  ? 44  GLN   C C   1 
ATOM   1934 O O   . GLN   B 2 62  ? 104.129 128.347 109.051 1.00 69.54  ? 44  GLN   C O   1 
ATOM   1935 C CB  . GLN   B 2 62  ? 102.664 129.766 111.139 1.00 69.54  ? 44  GLN   C CB  1 
ATOM   1936 N N   . MET   B 2 63  ? 105.786 129.829 109.423 1.00 63.16  ? 45  MET   C N   1 
ATOM   1937 C CA  . MET   B 2 63  ? 106.848 128.953 108.958 1.00 63.16  ? 45  MET   C CA  1 
ATOM   1938 C C   . MET   B 2 63  ? 107.976 128.944 109.977 1.00 63.16  ? 45  MET   C C   1 
ATOM   1939 O O   . MET   B 2 63  ? 108.327 129.984 110.537 1.00 63.16  ? 45  MET   C O   1 
ATOM   1940 C CB  . MET   B 2 63  ? 107.331 129.378 107.565 1.00 63.16  ? 45  MET   C CB  1 
ATOM   1941 C CG  . MET   B 2 63  ? 108.000 130.737 107.478 1.00 63.16  ? 45  MET   C CG  1 
ATOM   1942 S SD  . MET   B 2 63  ? 108.448 131.099 105.773 1.00 63.16  ? 45  MET   C SD  1 
ATOM   1943 C CE  . MET   B 2 63  ? 109.178 132.720 105.926 1.00 63.16  ? 45  MET   C CE  1 
ATOM   1944 N N   . ARG   B 2 64  ? 108.520 127.762 110.231 1.00 55.42  ? 46  ARG   C N   1 
ATOM   1945 C CA  . ARG   B 2 64  ? 109.459 127.560 111.321 1.00 55.42  ? 46  ARG   C CA  1 
ATOM   1946 C C   . ARG   B 2 64  ? 110.829 127.170 110.786 1.00 55.42  ? 46  ARG   C C   1 
ATOM   1947 O O   . ARG   B 2 64  ? 111.003 126.866 109.607 1.00 55.42  ? 46  ARG   C O   1 
ATOM   1948 C CB  . ARG   B 2 64  ? 108.948 126.488 112.291 1.00 55.42  ? 46  ARG   C CB  1 
ATOM   1949 N N   . THR   B 2 65  ? 111.805 127.179 111.687 1.00 54.37  ? 47  THR   C N   1 
ATOM   1950 C CA  . THR   B 2 65  ? 113.167 126.822 111.328 1.00 54.37  ? 47  THR   C CA  1 
ATOM   1951 C C   . THR   B 2 65  ? 113.253 125.363 110.899 1.00 54.37  ? 47  THR   C C   1 
ATOM   1952 O O   . THR   B 2 65  ? 112.558 124.496 111.434 1.00 54.37  ? 47  THR   C O   1 
ATOM   1953 C CB  . THR   B 2 65  ? 114.100 127.088 112.507 1.00 54.37  ? 47  THR   C CB  1 
ATOM   1954 O OG1 . THR   B 2 65  ? 115.428 126.674 112.172 1.00 54.37  ? 47  THR   C OG1 1 
ATOM   1955 C CG2 . THR   B 2 65  ? 113.633 126.341 113.746 1.00 54.37  ? 47  THR   C CG2 1 
ATOM   1956 N N   . ARG   B 2 66  ? 114.101 125.098 109.911 1.00 54.70  ? 48  ARG   C N   1 
ATOM   1957 C CA  . ARG   B 2 66  ? 114.313 123.754 109.391 1.00 54.70  ? 48  ARG   C CA  1 
ATOM   1958 C C   . ARG   B 2 66  ? 115.769 123.349 109.318 1.00 54.70  ? 48  ARG   C C   1 
ATOM   1959 O O   . ARG   B 2 66  ? 116.050 122.154 109.184 1.00 54.70  ? 48  ARG   C O   1 
ATOM   1960 C CB  . ARG   B 2 66  ? 113.706 123.614 107.992 1.00 54.70  ? 48  ARG   C CB  1 
ATOM   1961 C CG  . ARG   B 2 66  ? 112.253 124.006 107.908 1.00 54.70  ? 48  ARG   C CG  1 
ATOM   1962 C CD  . ARG   B 2 66  ? 111.366 122.834 108.240 1.00 54.70  ? 48  ARG   C CD  1 
ATOM   1963 N NE  . ARG   B 2 66  ? 109.959 123.203 108.240 1.00 54.70  ? 48  ARG   C NE  1 
ATOM   1964 C CZ  . ARG   B 2 66  ? 108.962 122.330 108.241 1.00 54.70  ? 48  ARG   C CZ  1 
ATOM   1965 N NH1 . ARG   B 2 66  ? 109.217 121.030 108.242 1.00 54.70  ? 48  ARG   C NH1 1 
ATOM   1966 N NH2 . ARG   B 2 66  ? 107.708 122.755 108.240 1.00 54.70  ? 48  ARG   C NH2 1 
ATOM   1967 N N   . ARG   B 2 67  ? 116.699 124.292 109.394 1.00 54.98  ? 49  ARG   C N   1 
ATOM   1968 C CA  . ARG   B 2 67  ? 118.120 124.006 109.360 1.00 54.98  ? 49  ARG   C CA  1 
ATOM   1969 C C   . ARG   B 2 67  ? 118.838 125.178 110.007 1.00 54.98  ? 49  ARG   C C   1 
ATOM   1970 O O   . ARG   B 2 67  ? 118.478 126.331 109.771 1.00 54.98  ? 49  ARG   C O   1 
ATOM   1971 C CB  . ARG   B 2 67  ? 118.597 123.797 107.922 1.00 54.98  ? 49  ARG   C CB  1 
ATOM   1972 C CG  . ARG   B 2 67  ? 119.842 122.970 107.790 1.00 54.98  ? 49  ARG   C CG  1 
ATOM   1973 C CD  . ARG   B 2 67  ? 119.507 121.507 107.628 1.00 54.98  ? 49  ARG   C CD  1 
ATOM   1974 N NE  . ARG   B 2 67  ? 118.523 121.270 106.583 1.00 54.98  ? 49  ARG   C NE  1 
ATOM   1975 C CZ  . ARG   B 2 67  ? 117.788 120.168 106.508 1.00 54.98  ? 49  ARG   C CZ  1 
ATOM   1976 N NH1 . ARG   B 2 67  ? 117.938 119.215 107.411 1.00 54.98  ? 49  ARG   C NH1 1 
ATOM   1977 N NH2 . ARG   B 2 67  ? 116.911 120.016 105.530 1.00 54.98  ? 49  ARG   C NH2 1 
ATOM   1978 N N   . THR   B 2 68  ? 119.834 124.882 110.830 1.00 53.72  ? 50  THR   C N   1 
ATOM   1979 C CA  . THR   B 2 68  ? 120.647 125.904 111.485 1.00 53.72  ? 50  THR   C CA  1 
ATOM   1980 C C   . THR   B 2 68  ? 122.099 125.650 111.104 1.00 53.72  ? 50  THR   C C   1 
ATOM   1981 O O   . THR   B 2 68  ? 122.740 124.744 111.639 1.00 53.72  ? 50  THR   C O   1 
ATOM   1982 C CB  . THR   B 2 68  ? 120.456 125.888 112.994 1.00 53.72  ? 50  THR   C CB  1 
ATOM   1983 O OG1 . THR   B 2 68  ? 119.080 126.139 113.303 1.00 53.72  ? 50  THR   C OG1 1 
ATOM   1984 C CG2 . THR   B 2 68  ? 121.316 126.961 113.644 1.00 53.72  ? 50  THR   C CG2 1 
ATOM   1985 N N   . LEU   B 2 69  ? 122.608 126.456 110.183 1.00 52.85  ? 51  LEU   C N   1 
ATOM   1986 C CA  . LEU   B 2 69  ? 123.928 126.254 109.596 1.00 52.85  ? 51  LEU   C CA  1 
ATOM   1987 C C   . LEU   B 2 69  ? 124.938 127.015 110.440 1.00 52.85  ? 51  LEU   C C   1 
ATOM   1988 O O   . LEU   B 2 69  ? 125.032 128.240 110.361 1.00 52.85  ? 51  LEU   C O   1 
ATOM   1989 C CB  . LEU   B 2 69  ? 123.944 126.720 108.146 1.00 52.85  ? 51  LEU   C CB  1 
ATOM   1990 C CG  . LEU   B 2 69  ? 123.200 125.880 107.110 1.00 52.85  ? 51  LEU   C CG  1 
ATOM   1991 C CD1 . LEU   B 2 69  ? 121.708 125.991 107.273 1.00 52.85  ? 51  LEU   C CD1 1 
ATOM   1992 C CD2 . LEU   B 2 69  ? 123.588 126.315 105.725 1.00 52.85  ? 51  LEU   C CD2 1 
ATOM   1993 N N   . ARG   B 2 70  ? 125.701 126.291 111.249 1.00 56.24  ? 52  ARG   C N   1 
ATOM   1994 C CA  . ARG   B 2 70  ? 126.645 126.897 112.171 1.00 56.24  ? 52  ARG   C CA  1 
ATOM   1995 C C   . ARG   B 2 70  ? 128.067 126.525 111.790 1.00 56.24  ? 52  ARG   C C   1 
ATOM   1996 O O   . ARG   B 2 70  ? 128.312 125.530 111.104 1.00 56.24  ? 52  ARG   C O   1 
ATOM   1997 C CB  . ARG   B 2 70  ? 126.367 126.472 113.613 1.00 56.24  ? 52  ARG   C CB  1 
ATOM   1998 C CG  . ARG   B 2 70  ? 126.647 125.024 113.895 1.00 56.24  ? 52  ARG   C CG  1 
ATOM   1999 C CD  . ARG   B 2 70  ? 126.206 124.679 115.294 1.00 56.24  ? 52  ARG   C CD  1 
ATOM   2000 N NE  . ARG   B 2 70  ? 124.790 124.960 115.487 1.00 56.24  ? 52  ARG   C NE  1 
ATOM   2001 C CZ  . ARG   B 2 70  ? 123.821 124.080 115.269 1.00 56.24  ? 52  ARG   C CZ  1 
ATOM   2002 N NH1 . ARG   B 2 70  ? 124.116 122.858 114.849 1.00 56.24  ? 52  ARG   C NH1 1 
ATOM   2003 N NH2 . ARG   B 2 70  ? 122.556 124.419 115.471 1.00 56.24  ? 52  ARG   C NH2 1 
ATOM   2004 N N   . GLY   B 2 71  ? 129.006 127.338 112.257 1.00 53.90  ? 53  GLY   C N   1 
ATOM   2005 C CA  . GLY   B 2 71  ? 130.395 127.163 111.904 1.00 53.90  ? 53  GLY   C CA  1 
ATOM   2006 C C   . GLY   B 2 71  ? 131.120 128.480 111.760 1.00 53.90  ? 53  GLY   C C   1 
ATOM   2007 O O   . GLY   B 2 71  ? 132.352 128.525 111.802 1.00 53.90  ? 53  GLY   C O   1 
ATOM   2008 N N   . HIS   B 2 72  ? 130.370 129.559 111.582 1.00 53.57  ? 54  HIS   C N   1 
ATOM   2009 C CA  . HIS   B 2 72  ? 130.959 130.884 111.525 1.00 53.57  ? 54  HIS   C CA  1 
ATOM   2010 C C   . HIS   B 2 72  ? 131.206 131.389 112.936 1.00 53.57  ? 54  HIS   C C   1 
ATOM   2011 O O   . HIS   B 2 72  ? 130.365 131.227 113.824 1.00 53.57  ? 54  HIS   C O   1 
ATOM   2012 C CB  . HIS   B 2 72  ? 130.043 131.849 110.776 1.00 53.57  ? 54  HIS   C CB  1 
ATOM   2013 C CG  . HIS   B 2 72  ? 130.311 131.925 109.305 1.00 53.57  ? 54  HIS   C CG  1 
ATOM   2014 N ND1 . HIS   B 2 72  ? 131.576 132.080 108.784 1.00 53.57  ? 54  HIS   C ND1 1 
ATOM   2015 C CD2 . HIS   B 2 72  ? 129.473 131.879 108.245 1.00 53.57  ? 54  HIS   C CD2 1 
ATOM   2016 C CE1 . HIS   B 2 72  ? 131.504 132.118 107.466 1.00 53.57  ? 54  HIS   C CE1 1 
ATOM   2017 N NE2 . HIS   B 2 72  ? 130.240 132.000 107.115 1.00 53.57  ? 54  HIS   C NE2 1 
ATOM   2018 N N   . LEU   B 2 73  ? 132.367 132.003 113.145 1.00 56.21  ? 55  LEU   C N   1 
ATOM   2019 C CA  . LEU   B 2 73  ? 132.756 132.483 114.462 1.00 56.21  ? 55  LEU   C CA  1 
ATOM   2020 C C   . LEU   B 2 73  ? 132.652 133.995 114.601 1.00 56.21  ? 55  LEU   C C   1 
ATOM   2021 O O   . LEU   B 2 73  ? 133.130 134.549 115.594 1.00 56.21  ? 55  LEU   C O   1 
ATOM   2022 C CB  . LEU   B 2 73  ? 134.174 132.018 114.784 1.00 56.21  ? 55  LEU   C CB  1 
ATOM   2023 C CG  . LEU   B 2 73  ? 134.390 130.520 114.591 1.00 56.21  ? 55  LEU   C CG  1 
ATOM   2024 C CD1 . LEU   B 2 73  ? 135.859 130.208 114.400 1.00 56.21  ? 55  LEU   C CD1 1 
ATOM   2025 C CD2 . LEU   B 2 73  ? 133.824 129.749 115.772 1.00 56.21  ? 55  LEU   C CD2 1 
ATOM   2026 N N   . ALA   B 2 74  ? 132.036 134.674 113.641 1.00 53.55  ? 56  ALA   C N   1 
ATOM   2027 C CA  . ALA   B 2 74  ? 131.916 136.121 113.675 1.00 53.55  ? 56  ALA   C CA  1 
ATOM   2028 C C   . ALA   B 2 74  ? 130.621 136.517 112.990 1.00 53.55  ? 56  ALA   C C   1 
ATOM   2029 O O   . ALA   B 2 74  ? 129.879 135.675 112.482 1.00 53.55  ? 56  ALA   C O   1 
ATOM   2030 C CB  . ALA   B 2 74  ? 133.120 136.794 113.014 1.00 53.55  ? 56  ALA   C CB  1 
ATOM   2031 N N   . LYS   B 2 75  ? 130.354 137.815 112.984 1.00 53.82  ? 57  LYS   C N   1 
ATOM   2032 C CA  . LYS   B 2 75  ? 129.145 138.336 112.372 1.00 53.82  ? 57  LYS   C CA  1 
ATOM   2033 C C   . LYS   B 2 75  ? 129.063 137.934 110.907 1.00 53.82  ? 57  LYS   C C   1 
ATOM   2034 O O   . LYS   B 2 75  ? 130.045 138.017 110.167 1.00 53.82  ? 57  LYS   C O   1 
ATOM   2035 C CB  . LYS   B 2 75  ? 129.115 139.859 112.487 1.00 53.82  ? 57  LYS   C CB  1 
ATOM   2036 C CG  . LYS   B 2 75  ? 129.366 140.389 113.878 1.00 53.82  ? 57  LYS   C CG  1 
ATOM   2037 C CD  . LYS   B 2 75  ? 129.360 141.906 113.895 1.00 53.82  ? 57  LYS   C CD  1 
ATOM   2038 C CE  . LYS   B 2 75  ? 130.654 142.468 113.334 1.00 53.82  ? 57  LYS   C CE  1 
ATOM   2039 N NZ  . LYS   B 2 75  ? 131.625 142.809 114.410 1.00 53.82  ? 57  LYS   C NZ  1 
ATOM   2040 N N   . ILE   B 2 76  ? 127.879 137.507 110.487 1.00 51.22  ? 58  ILE   C N   1 
ATOM   2041 C CA  . ILE   B 2 76  ? 127.619 137.187 109.091 1.00 51.22  ? 58  ILE   C CA  1 
ATOM   2042 C C   . ILE   B 2 76  ? 127.063 138.434 108.423 1.00 51.22  ? 58  ILE   C C   1 
ATOM   2043 O O   . ILE   B 2 76  ? 126.025 138.955 108.839 1.00 51.22  ? 58  ILE   C O   1 
ATOM   2044 C CB  . ILE   B 2 76  ? 126.648 136.007 108.967 1.00 51.22  ? 58  ILE   C CB  1 
ATOM   2045 C CG1 . ILE   B 2 76  ? 127.381 134.691 109.181 1.00 51.22  ? 58  ILE   C CG1 1 
ATOM   2046 C CG2 . ILE   B 2 76  ? 125.980 136.004 107.619 1.00 51.22  ? 58  ILE   C CG2 1 
ATOM   2047 C CD1 . ILE   B 2 76  ? 126.465 133.506 109.267 1.00 51.22  ? 58  ILE   C CD1 1 
ATOM   2048 N N   . TYR   B 2 77  ? 127.755 138.929 107.401 1.00 52.98  ? 59  TYR   C N   1 
ATOM   2049 C CA  . TYR   B 2 77  ? 127.325 140.153 106.737 1.00 52.98  ? 59  TYR   C CA  1 
ATOM   2050 C C   . TYR   B 2 77  ? 126.522 139.920 105.471 1.00 52.98  ? 59  TYR   C C   1 
ATOM   2051 O O   . TYR   B 2 77  ? 125.545 140.633 105.235 1.00 52.98  ? 59  TYR   C O   1 
ATOM   2052 C CB  . TYR   B 2 77  ? 128.516 141.049 106.412 1.00 52.98  ? 59  TYR   C CB  1 
ATOM   2053 C CG  . TYR   B 2 77  ? 128.915 141.917 107.569 1.00 52.98  ? 59  TYR   C CG  1 
ATOM   2054 C CD1 . TYR   B 2 77  ? 128.196 141.887 108.753 1.00 52.98  ? 59  TYR   C CD1 1 
ATOM   2055 C CD2 . TYR   B 2 77  ? 129.956 142.815 107.463 1.00 52.98  ? 59  TYR   C CD2 1 
ATOM   2056 C CE1 . TYR   B 2 77  ? 128.542 142.685 109.812 1.00 52.98  ? 59  TYR   C CE1 1 
ATOM   2057 C CE2 . TYR   B 2 77  ? 130.301 143.628 108.515 1.00 52.98  ? 59  TYR   C CE2 1 
ATOM   2058 C CZ  . TYR   B 2 77  ? 129.590 143.557 109.690 1.00 52.98  ? 59  TYR   C CZ  1 
ATOM   2059 O OH  . TYR   B 2 77  ? 129.919 144.356 110.756 1.00 52.98  ? 59  TYR   C OH  1 
ATOM   2060 N N   . ALA   B 2 78  ? 126.899 138.956 104.643 1.00 49.15  ? 60  ALA   C N   1 
ATOM   2061 C CA  . ALA   B 2 78  ? 126.149 138.685 103.430 1.00 49.15  ? 60  ALA   C CA  1 
ATOM   2062 C C   . ALA   B 2 78  ? 125.969 137.188 103.259 1.00 49.15  ? 60  ALA   C C   1 
ATOM   2063 O O   . ALA   B 2 78  ? 126.763 136.390 103.760 1.00 49.15  ? 60  ALA   C O   1 
ATOM   2064 C CB  . ALA   B 2 78  ? 126.841 139.272 102.199 1.00 49.15  ? 60  ALA   C CB  1 
ATOM   2065 N N   . MET   B 2 79  ? 124.900 136.817 102.563 1.00 45.89  ? 61  MET   C N   1 
ATOM   2066 C CA  . MET   B 2 79  ? 124.731 135.468 102.058 1.00 45.89  ? 61  MET   C CA  1 
ATOM   2067 C C   . MET   B 2 79  ? 124.070 135.554 100.697 1.00 45.89  ? 61  MET   C C   1 
ATOM   2068 O O   . MET   B 2 79  ? 123.414 136.541 100.365 1.00 45.89  ? 61  MET   C O   1 
ATOM   2069 C CB  . MET   B 2 79  ? 123.911 134.577 103.001 1.00 45.89  ? 61  MET   C CB  1 
ATOM   2070 C CG  . MET   B 2 79  ? 122.432 134.881 103.105 1.00 45.89  ? 61  MET   C CG  1 
ATOM   2071 S SD  . MET   B 2 79  ? 121.394 134.136 101.837 1.00 45.89  ? 61  MET   C SD  1 
ATOM   2072 C CE  . MET   B 2 79  ? 121.740 132.399 102.089 1.00 45.89  ? 61  MET   C CE  1 
ATOM   2073 N N   . HIS   B 2 80  ? 124.248 134.508 99.907  1.00 44.18  ? 62  HIS   C N   1 
ATOM   2074 C CA  . HIS   B 2 80  ? 123.673 134.451 98.579  1.00 44.18  ? 62  HIS   C CA  1 
ATOM   2075 C C   . HIS   B 2 80  ? 123.264 133.014 98.303  1.00 44.18  ? 62  HIS   C C   1 
ATOM   2076 O O   . HIS   B 2 80  ? 123.730 132.085 98.957  1.00 44.18  ? 62  HIS   C O   1 
ATOM   2077 C CB  . HIS   B 2 80  ? 124.659 134.964 97.533  1.00 44.18  ? 62  HIS   C CB  1 
ATOM   2078 C CG  . HIS   B 2 80  ? 124.007 135.544 96.322  1.00 44.18  ? 62  HIS   C CG  1 
ATOM   2079 N ND1 . HIS   B 2 80  ? 124.679 135.748 95.139  1.00 44.18  ? 62  HIS   C ND1 1 
ATOM   2080 C CD2 . HIS   B 2 80  ? 122.748 135.988 96.118  1.00 44.18  ? 62  HIS   C CD2 1 
ATOM   2081 C CE1 . HIS   B 2 80  ? 123.857 136.275 94.253  1.00 44.18  ? 62  HIS   C CE1 1 
ATOM   2082 N NE2 . HIS   B 2 80  ? 122.678 136.427 94.821  1.00 44.18  ? 62  HIS   C NE2 1 
ATOM   2083 N N   . TRP   B 2 81  ? 122.378 132.839 97.335  1.00 45.40  ? 63  TRP   C N   1 
ATOM   2084 C CA  . TRP   B 2 81  ? 121.864 131.535 96.953  1.00 45.40  ? 63  TRP   C CA  1 
ATOM   2085 C C   . TRP   B 2 81  ? 122.320 131.215 95.542  1.00 45.40  ? 63  TRP   C C   1 
ATOM   2086 O O   . TRP   B 2 81  ? 122.308 132.084 94.669  1.00 45.40  ? 63  TRP   C O   1 
ATOM   2087 C CB  . TRP   B 2 81  ? 120.338 131.517 96.999  1.00 45.40  ? 63  TRP   C CB  1 
ATOM   2088 C CG  . TRP   B 2 81  ? 119.712 131.075 98.275  1.00 45.40  ? 63  TRP   C CG  1 
ATOM   2089 C CD1 . TRP   B 2 81  ? 118.978 131.832 99.121  1.00 45.40  ? 63  TRP   C CD1 1 
ATOM   2090 C CD2 . TRP   B 2 81  ? 119.716 129.758 98.818  1.00 45.40  ? 63  TRP   C CD2 1 
ATOM   2091 N NE1 . TRP   B 2 81  ? 118.543 131.081 100.173 1.00 45.40  ? 63  TRP   C NE1 1 
ATOM   2092 C CE2 . TRP   B 2 81  ? 118.983 129.797 100.008 1.00 45.40  ? 63  TRP   C CE2 1 
ATOM   2093 C CE3 . TRP   B 2 81  ? 120.281 128.551 98.418  1.00 45.40  ? 63  TRP   C CE3 1 
ATOM   2094 C CZ2 . TRP   B 2 81  ? 118.800 128.687 100.799 1.00 45.40  ? 63  TRP   C CZ2 1 
ATOM   2095 C CZ3 . TRP   B 2 81  ? 120.095 127.449 99.205  1.00 45.40  ? 63  TRP   C CZ3 1 
ATOM   2096 C CH2 . TRP   B 2 81  ? 119.362 127.523 100.382 1.00 45.40  ? 63  TRP   C CH2 1 
ATOM   2097 N N   . GLY   B 2 82  ? 122.735 129.980 95.319  1.00 52.12  ? 64  GLY   C N   1 
ATOM   2098 C CA  . GLY   B 2 82  ? 123.026 129.548 93.973  1.00 52.12  ? 64  GLY   C CA  1 
ATOM   2099 C C   . GLY   B 2 82  ? 121.762 129.360 93.161  1.00 52.12  ? 64  GLY   C C   1 
ATOM   2100 O O   . GLY   B 2 82  ? 120.668 129.178 93.693  1.00 52.12  ? 64  GLY   C O   1 
ATOM   2101 N N   . THR   B 2 83  ? 121.917 129.419 91.838  1.00 57.24  ? 65  THR   C N   1 
ATOM   2102 C CA  . THR   B 2 83  ? 120.771 129.242 90.952  1.00 57.24  ? 65  THR   C CA  1 
ATOM   2103 C C   . THR   B 2 83  ? 120.142 127.869 91.127  1.00 57.24  ? 65  THR   C C   1 
ATOM   2104 O O   . THR   B 2 83  ? 118.926 127.718 90.968  1.00 57.24  ? 65  THR   C O   1 
ATOM   2105 C CB  . THR   B 2 83  ? 121.195 129.449 89.502  1.00 57.24  ? 65  THR   C CB  1 
ATOM   2106 O OG1 . THR   B 2 83  ? 121.889 130.696 89.384  1.00 57.24  ? 65  THR   C OG1 1 
ATOM   2107 C CG2 . THR   B 2 83  ? 119.980 129.470 88.583  1.00 57.24  ? 65  THR   C CG2 1 
ATOM   2108 N N   . ASP   B 2 84  ? 120.945 126.859 91.469  1.00 56.99  ? 66  ASP   C N   1 
ATOM   2109 C CA  . ASP   B 2 84  ? 120.418 125.523 91.709  1.00 56.99  ? 66  ASP   C CA  1 
ATOM   2110 C C   . ASP   B 2 84  ? 119.572 125.442 92.970  1.00 56.99  ? 66  ASP   C C   1 
ATOM   2111 O O   . ASP   B 2 84  ? 118.897 124.430 93.175  1.00 56.99  ? 66  ASP   C O   1 
ATOM   2112 C CB  . ASP   B 2 84  ? 121.565 124.515 91.788  1.00 56.99  ? 66  ASP   C CB  1 
ATOM   2113 C CG  . ASP   B 2 84  ? 122.505 124.790 92.945  1.00 56.99  ? 66  ASP   C CG  1 
ATOM   2114 O OD1 . ASP   B 2 84  ? 123.122 123.828 93.450  1.00 56.99  ? 66  ASP   C OD1 1 
ATOM   2115 O OD2 . ASP   B 2 84  ? 122.633 125.966 93.345  1.00 56.99  ? 66  ASP   C OD2 1 
ATOM   2116 N N   . SER   B 2 85  ? 119.608 126.470 93.816  1.00 55.94  ? 67  SER   C N   1 
ATOM   2117 C CA  . SER   B 2 85  ? 118.803 126.546 95.032  1.00 55.94  ? 67  SER   C CA  1 
ATOM   2118 C C   . SER   B 2 85  ? 119.174 125.466 96.039  1.00 55.94  ? 67  SER   C C   1 
ATOM   2119 O O   . SER   B 2 85  ? 118.358 125.085 96.878  1.00 55.94  ? 67  SER   C O   1 
ATOM   2120 C CB  . SER   B 2 85  ? 117.308 126.490 94.712  1.00 55.94  ? 67  SER   C CB  1 
ATOM   2121 O OG  . SER   B 2 85  ? 116.913 127.601 93.924  1.00 55.94  ? 67  SER   C OG  1 
ATOM   2122 N N   . ARG   B 2 86  ? 120.400 124.962 95.979  1.00 52.00  ? 68  ARG   C N   1 
ATOM   2123 C CA  . ARG   B 2 86  ? 120.907 124.070 97.010  1.00 52.00  ? 68  ARG   C CA  1 
ATOM   2124 C C   . ARG   B 2 86  ? 122.165 124.573 97.692  1.00 52.00  ? 68  ARG   C C   1 
ATOM   2125 O O   . ARG   B 2 86  ? 122.382 124.250 98.857  1.00 52.00  ? 68  ARG   C O   1 
ATOM   2126 C CB  . ARG   B 2 86  ? 121.184 122.664 96.447  1.00 52.00  ? 68  ARG   C CB  1 
ATOM   2127 C CG  . ARG   B 2 86  ? 121.429 121.639 97.544  1.00 52.00  ? 68  ARG   C CG  1 
ATOM   2128 C CD  . ARG   B 2 86  ? 121.412 120.192 97.090  1.00 52.00  ? 68  ARG   C CD  1 
ATOM   2129 N NE  . ARG   B 2 86  ? 121.406 119.314 98.260  1.00 52.00  ? 68  ARG   C NE  1 
ATOM   2130 C CZ  . ARG   B 2 86  ? 122.062 118.166 98.381  1.00 52.00  ? 68  ARG   C CZ  1 
ATOM   2131 N NH1 . ARG   B 2 86  ? 121.972 117.469 99.504  1.00 52.00  ? 68  ARG   C NH1 1 
ATOM   2132 N NH2 . ARG   B 2 86  ? 122.768 117.685 97.382  1.00 52.00  ? 68  ARG   C NH2 1 
ATOM   2133 N N   . LEU   B 2 87  ? 122.984 125.363 97.015  1.00 48.10  ? 69  LEU   C N   1 
ATOM   2134 C CA  . LEU   B 2 87  ? 124.226 125.859 97.578  1.00 48.10  ? 69  LEU   C CA  1 
ATOM   2135 C C   . LEU   B 2 87  ? 124.069 127.327 97.932  1.00 48.10  ? 69  LEU   C C   1 
ATOM   2136 O O   . LEU   B 2 87  ? 123.360 128.065 97.247  1.00 48.10  ? 69  LEU   C O   1 
ATOM   2137 C CB  . LEU   B 2 87  ? 125.387 125.669 96.600  1.00 48.10  ? 69  LEU   C CB  1 
ATOM   2138 C CG  . LEU   B 2 87  ? 125.802 124.243 96.231  1.00 48.10  ? 69  LEU   C CG  1 
ATOM   2139 C CD1 . LEU   B 2 87  ? 126.939 124.261 95.244  1.00 48.10  ? 69  LEU   C CD1 1 
ATOM   2140 C CD2 . LEU   B 2 87  ? 126.198 123.458 97.453  1.00 48.10  ? 69  LEU   C CD2 1 
ATOM   2141 N N   . LEU   B 2 88  ? 124.707 127.742 99.020  1.00 44.02  ? 70  LEU   C N   1 
ATOM   2142 C CA  . LEU   B 2 88  ? 124.673 129.136 99.419  1.00 44.02  ? 70  LEU   C CA  1 
ATOM   2143 C C   . LEU   B 2 88  ? 126.035 129.550 99.945  1.00 44.02  ? 70  LEU   C C   1 
ATOM   2144 O O   . LEU   B 2 88  ? 126.668 128.816 100.704 1.00 44.02  ? 70  LEU   C O   1 
ATOM   2145 C CB  . LEU   B 2 88  ? 123.576 129.401 100.460 1.00 44.02  ? 70  LEU   C CB  1 
ATOM   2146 C CG  . LEU   B 2 88  ? 123.547 128.863 101.882 1.00 44.02  ? 70  LEU   C CG  1 
ATOM   2147 C CD1 . LEU   B 2 88  ? 124.286 129.810 102.784 1.00 44.02  ? 70  LEU   C CD1 1 
ATOM   2148 C CD2 . LEU   B 2 88  ? 122.125 128.712 102.351 1.00 44.02  ? 70  LEU   C CD2 1 
ATOM   2149 N N   . VAL   B 2 89  ? 126.483 130.722 99.524  1.00 43.47  ? 71  VAL   C N   1 
ATOM   2150 C CA  . VAL   B 2 89  ? 127.744 131.291 99.972  1.00 43.47  ? 71  VAL   C CA  1 
ATOM   2151 C C   . VAL   B 2 89  ? 127.469 132.236 101.128 1.00 43.47  ? 71  VAL   C C   1 
ATOM   2152 O O   . VAL   B 2 89  ? 126.428 132.895 101.186 1.00 43.47  ? 71  VAL   C O   1 
ATOM   2153 C CB  . VAL   B 2 89  ? 128.480 132.000 98.818  1.00 43.47  ? 71  VAL   C CB  1 
ATOM   2154 C CG1 . VAL   B 2 89  ? 127.790 133.277 98.448  1.00 43.47  ? 71  VAL   C CG1 1 
ATOM   2155 C CG2 . VAL   B 2 89  ? 129.920 132.253 99.187  1.00 43.47  ? 71  VAL   C CG2 1 
ATOM   2156 N N   . SER   B 2 90  ? 128.392 132.278 102.080 1.00 45.24  ? 72  SER   C N   1 
ATOM   2157 C CA  . SER   B 2 90  ? 128.283 133.164 103.227 1.00 45.24  ? 72  SER   C CA  1 
ATOM   2158 C C   . SER   B 2 90  ? 129.652 133.723 103.560 1.00 45.24  ? 72  SER   C C   1 
ATOM   2159 O O   . SER   B 2 90  ? 130.640 132.987 103.567 1.00 45.24  ? 72  SER   C O   1 
ATOM   2160 C CB  . SER   B 2 90  ? 127.716 132.437 104.443 1.00 45.24  ? 72  SER   C CB  1 
ATOM   2161 O OG  . SER   B 2 90  ? 126.530 131.749 104.107 1.00 45.24  ? 72  SER   C OG  1 
ATOM   2162 N N   . ALA   B 2 91  ? 129.712 135.019 103.840 1.00 47.13  ? 73  ALA   C N   1 
ATOM   2163 C CA  . ALA   B 2 91  ? 130.948 135.673 104.239 1.00 47.13  ? 73  ALA   C CA  1 
ATOM   2164 C C   . ALA   B 2 91  ? 130.764 136.301 105.606 1.00 47.13  ? 73  ALA   C C   1 
ATOM   2165 O O   . ALA   B 2 91  ? 129.750 136.952 105.861 1.00 47.13  ? 73  ALA   C O   1 
ATOM   2166 C CB  . ALA   B 2 91  ? 131.378 136.734 103.235 1.00 47.13  ? 73  ALA   C CB  1 
ATOM   2167 N N   . SER   B 2 92  ? 131.740 136.098 106.478 1.00 51.47  ? 74  SER   C N   1 
ATOM   2168 C CA  . SER   B 2 92  ? 131.711 136.622 107.829 1.00 51.47  ? 74  SER   C CA  1 
ATOM   2169 C C   . SER   B 2 92  ? 132.938 137.487 108.061 1.00 51.47  ? 74  SER   C C   1 
ATOM   2170 O O   . SER   B 2 92  ? 133.943 137.379 107.357 1.00 51.47  ? 74  SER   C O   1 
ATOM   2171 C CB  . SER   B 2 92  ? 131.650 135.501 108.865 1.00 51.47  ? 74  SER   C CB  1 
ATOM   2172 O OG  . SER   B 2 92  ? 132.937 134.993 109.137 1.00 51.47  ? 74  SER   C OG  1 
ATOM   2173 N N   . GLN   B 2 93  ? 132.842 138.343 109.049 1.00 54.64  ? 75  GLN   C N   1 
ATOM   2174 C CA  . GLN   B 2 93  ? 133.878 139.317 109.348 1.00 54.64  ? 75  GLN   C CA  1 
ATOM   2175 C C   . GLN   B 2 93  ? 135.109 138.709 109.944 1.00 54.64  ? 75  GLN   C C   1 
ATOM   2176 O O   . GLN   B 2 93  ? 135.963 139.478 110.389 1.00 54.64  ? 75  GLN   C O   1 
ATOM   2177 C CB  . GLN   B 2 93  ? 133.324 140.385 110.290 1.00 54.64  ? 75  GLN   C CB  1 
ATOM   2178 C CG  . GLN   B 2 93  ? 132.760 141.600 109.588 1.00 54.64  ? 75  GLN   C CG  1 
ATOM   2179 C CD  . GLN   B 2 93  ? 133.836 142.445 108.946 1.00 54.64  ? 75  GLN   C CD  1 
ATOM   2180 O OE1 . GLN   B 2 93  ? 135.021 142.267 109.221 1.00 54.64  ? 75  GLN   C OE1 1 
ATOM   2181 N NE2 . GLN   B 2 93  ? 133.432 143.369 108.083 1.00 54.64  ? 75  GLN   C NE2 1 
ATOM   2182 N N   . ASP   B 2 94  ? 135.263 137.390 110.002 1.00 56.11  ? 76  ASP   C N   1 
ATOM   2183 C CA  . ASP   B 2 94  ? 136.494 136.780 110.474 1.00 56.11  ? 76  ASP   C CA  1 
ATOM   2184 C C   . ASP   B 2 94  ? 137.427 136.393 109.340 1.00 56.11  ? 76  ASP   C C   1 
ATOM   2185 O O   . ASP   B 2 94  ? 138.561 135.985 109.599 1.00 56.11  ? 76  ASP   C O   1 
ATOM   2186 C CB  . ASP   B 2 94  ? 136.185 135.553 111.336 1.00 56.11  ? 76  ASP   C CB  1 
ATOM   2187 C CG  . ASP   B 2 94  ? 135.521 134.446 110.558 1.00 56.11  ? 76  ASP   C CG  1 
ATOM   2188 O OD1 . ASP   B 2 94  ? 134.994 134.717 109.463 1.00 56.11  ? 76  ASP   C OD1 1 
ATOM   2189 O OD2 . ASP   B 2 94  ? 135.520 133.297 111.046 1.00 56.11  ? 76  ASP   C OD2 1 
ATOM   2190 N N   . GLY   B 2 95  ? 136.981 136.508 108.098 1.00 54.42  ? 77  GLY   C N   1 
ATOM   2191 C CA  . GLY   B 2 95  ? 137.852 136.295 106.967 1.00 54.42  ? 77  GLY   C CA  1 
ATOM   2192 C C   . GLY   B 2 95  ? 137.691 134.950 106.303 1.00 54.42  ? 77  GLY   C C   1 
ATOM   2193 O O   . GLY   B 2 95  ? 138.688 134.340 105.908 1.00 54.42  ? 77  GLY   C O   1 
ATOM   2194 N N   . LYS   B 2 96  ? 136.456 134.474 106.155 1.00 52.06  ? 78  LYS   C N   1 
ATOM   2195 C CA  . LYS   B 2 96  ? 136.238 133.200 105.484 1.00 52.06  ? 78  LYS   C CA  1 
ATOM   2196 C C   . LYS   B 2 96  ? 134.886 133.171 104.794 1.00 52.06  ? 78  LYS   C C   1 
ATOM   2197 O O   . LYS   B 2 96  ? 133.869 133.515 105.397 1.00 52.06  ? 78  LYS   C O   1 
ATOM   2198 C CB  . LYS   B 2 96  ? 136.362 132.037 106.471 1.00 52.06  ? 78  LYS   C CB  1 
ATOM   2199 C CG  . LYS   B 2 96  ? 137.748 131.439 106.479 1.00 52.06  ? 78  LYS   C CG  1 
ATOM   2200 C CD  . LYS   B 2 96  ? 137.858 130.240 107.374 1.00 52.06  ? 78  LYS   C CD  1 
ATOM   2201 C CE  . LYS   B 2 96  ? 139.274 129.708 107.385 1.00 52.06  ? 78  LYS   C CE  1 
ATOM   2202 N NZ  . LYS   B 2 96  ? 140.274 130.811 107.397 1.00 52.06  ? 78  LYS   C NZ  1 
ATOM   2203 N N   . LEU   B 2 97  ? 134.895 132.776 103.527 1.00 47.74  ? 79  LEU   C N   1 
ATOM   2204 C CA  . LEU   B 2 97  ? 133.690 132.436 102.789 1.00 47.74  ? 79  LEU   C CA  1 
ATOM   2205 C C   . LEU   B 2 97  ? 133.421 130.952 102.956 1.00 47.74  ? 79  LEU   C C   1 
ATOM   2206 O O   . LEU   B 2 97  ? 134.348 130.140 102.946 1.00 47.74  ? 79  LEU   C O   1 
ATOM   2207 C CB  . LEU   B 2 97  ? 133.846 132.756 101.302 1.00 47.74  ? 79  LEU   C CB  1 
ATOM   2208 C CG  . LEU   B 2 97  ? 133.842 134.175 100.749 1.00 47.74  ? 79  LEU   C CG  1 
ATOM   2209 C CD1 . LEU   B 2 97  ? 134.754 134.242 99.548  1.00 47.74  ? 79  LEU   C CD1 1 
ATOM   2210 C CD2 . LEU   B 2 97  ? 132.462 134.596 100.355 1.00 47.74  ? 79  LEU   C CD2 1 
ATOM   2211 N N   . ILE   B 2 98  ? 132.156 130.594 103.107 1.00 44.82  ? 80  ILE   C N   1 
ATOM   2212 C CA  . ILE   B 2 98  ? 131.761 129.202 103.241 1.00 44.82  ? 80  ILE   C CA  1 
ATOM   2213 C C   . ILE   B 2 98  ? 130.642 128.918 102.257 1.00 44.82  ? 80  ILE   C C   1 
ATOM   2214 O O   . ILE   B 2 98  ? 129.689 129.695 102.154 1.00 44.82  ? 80  ILE   C O   1 
ATOM   2215 C CB  . ILE   B 2 98  ? 131.328 128.860 104.676 1.00 44.82  ? 80  ILE   C CB  1 
ATOM   2216 C CG1 . ILE   B 2 98  ? 132.496 129.046 105.632 1.00 44.82  ? 80  ILE   C CG1 1 
ATOM   2217 C CG2 . ILE   B 2 98  ? 130.845 127.436 104.759 1.00 44.82  ? 80  ILE   C CG2 1 
ATOM   2218 C CD1 . ILE   B 2 98  ? 132.188 128.642 107.026 1.00 44.82  ? 80  ILE   C CD1 1 
ATOM   2219 N N   . ILE   B 2 99  ? 130.764 127.815 101.529 1.00 44.35  ? 81  ILE   C N   1 
ATOM   2220 C CA  . ILE   B 2 99  ? 129.751 127.358 100.591 1.00 44.35  ? 81  ILE   C CA  1 
ATOM   2221 C C   . ILE   B 2 99  ? 129.056 126.152 101.201 1.00 44.35  ? 81  ILE   C C   1 
ATOM   2222 O O   . ILE   B 2 99  ? 129.713 125.186 101.600 1.00 44.35  ? 81  ILE   C O   1 
ATOM   2223 C CB  . ILE   B 2 99  ? 130.369 127.028 99.226  1.00 44.35  ? 81  ILE   C CB  1 
ATOM   2224 C CG1 . ILE   B 2 99  ? 131.120 128.249 98.706  1.00 44.35  ? 81  ILE   C CG1 1 
ATOM   2225 C CG2 . ILE   B 2 99  ? 129.306 126.591 98.260  1.00 44.35  ? 81  ILE   C CG2 1 
ATOM   2226 C CD1 . ILE   B 2 99  ? 131.440 128.195 97.263  1.00 44.35  ? 81  ILE   C CD1 1 
ATOM   2227 N N   . TRP   B 2 100 ? 127.734 126.214 101.283 1.00 45.99  ? 82  TRP   C N   1 
ATOM   2228 C CA  . TRP   B 2 100 ? 126.943 125.297 102.087 1.00 45.99  ? 82  TRP   C CA  1 
ATOM   2229 C C   . TRP   B 2 100 ? 126.085 124.394 101.220 1.00 45.99  ? 82  TRP   C C   1 
ATOM   2230 O O   . TRP   B 2 100 ? 125.528 124.829 100.211 1.00 45.99  ? 82  TRP   C O   1 
ATOM   2231 C CB  . TRP   B 2 100 ? 126.014 126.051 103.037 1.00 45.99  ? 82  TRP   C CB  1 
ATOM   2232 C CG  . TRP   B 2 100 ? 126.678 126.856 104.084 1.00 45.99  ? 82  TRP   C CG  1 
ATOM   2233 C CD1 . TRP   B 2 100 ? 127.032 128.159 104.002 1.00 45.99  ? 82  TRP   C CD1 1 
ATOM   2234 C CD2 . TRP   B 2 100 ? 127.033 126.424 105.395 1.00 45.99  ? 82  TRP   C CD2 1 
ATOM   2235 N NE1 . TRP   B 2 100 ? 127.602 128.568 105.175 1.00 45.99  ? 82  TRP   C NE1 1 
ATOM   2236 C CE2 . TRP   B 2 100 ? 127.610 127.517 106.049 1.00 45.99  ? 82  TRP   C CE2 1 
ATOM   2237 C CE3 . TRP   B 2 100 ? 126.921 125.215 106.078 1.00 45.99  ? 82  TRP   C CE3 1 
ATOM   2238 C CZ2 . TRP   B 2 100 ? 128.082 127.439 107.343 1.00 45.99  ? 82  TRP   C CZ2 1 
ATOM   2239 C CZ3 . TRP   B 2 100 ? 127.389 125.141 107.360 1.00 45.99  ? 82  TRP   C CZ3 1 
ATOM   2240 C CH2 . TRP   B 2 100 ? 127.961 126.244 107.981 1.00 45.99  ? 82  TRP   C CH2 1 
ATOM   2241 N N   . ASP   B 2 101 ? 125.966 123.142 101.641 1.00 51.14  ? 83  ASP   C N   1 
ATOM   2242 C CA  . ASP   B 2 101 ? 124.959 122.225 101.123 1.00 51.14  ? 83  ASP   C CA  1 
ATOM   2243 C C   . ASP   B 2 101 ? 123.759 122.320 102.053 1.00 51.14  ? 83  ASP   C C   1 
ATOM   2244 O O   . ASP   B 2 101 ? 123.764 121.764 103.153 1.00 51.14  ? 83  ASP   C O   1 
ATOM   2245 C CB  . ASP   B 2 101 ? 125.510 120.809 101.049 1.00 51.14  ? 83  ASP   C CB  1 
ATOM   2246 C CG  . ASP   B 2 101 ? 124.591 119.871 100.321 1.00 51.14  ? 83  ASP   C CG  1 
ATOM   2247 O OD1 . ASP   B 2 101 ? 124.867 118.655 100.319 1.00 51.14  ? 83  ASP   C OD1 1 
ATOM   2248 O OD2 . ASP   B 2 101 ? 123.594 120.348 99.747  1.00 51.14  ? 83  ASP   C OD2 1 
ATOM   2249 N N   . SER   B 2 102 ? 122.727 123.034 101.610 1.00 51.28  ? 84  SER   C N   1 
ATOM   2250 C CA  . SER   B 2 102 ? 121.623 123.376 102.497 1.00 51.28  ? 84  SER   C CA  1 
ATOM   2251 C C   . SER   B 2 102 ? 120.857 122.144 102.955 1.00 51.28  ? 84  SER   C C   1 
ATOM   2252 O O   . SER   B 2 102 ? 120.467 122.052 104.124 1.00 51.28  ? 84  SER   C O   1 
ATOM   2253 C CB  . SER   B 2 102 ? 120.698 124.357 101.799 1.00 51.28  ? 84  SER   C CB  1 
ATOM   2254 O OG  . SER   B 2 102 ? 121.438 125.457 101.314 1.00 51.28  ? 84  SER   C OG  1 
ATOM   2255 N N   . TYR   B 2 103 ? 120.626 121.189 102.053 1.00 54.36  ? 85  TYR   C N   1 
ATOM   2256 C CA  . TYR   B 2 103 ? 119.836 120.017 102.406 1.00 54.36  ? 85  TYR   C CA  1 
ATOM   2257 C C   . TYR   B 2 103 ? 120.515 119.149 103.454 1.00 54.36  ? 85  TYR   C C   1 
ATOM   2258 O O   . TYR   B 2 103 ? 119.843 118.334 104.091 1.00 54.36  ? 85  TYR   C O   1 
ATOM   2259 C CB  . TYR   B 2 103 ? 119.551 119.162 101.176 1.00 54.36  ? 85  TYR   C CB  1 
ATOM   2260 C CG  . TYR   B 2 103 ? 118.716 119.807 100.096 1.00 54.36  ? 85  TYR   C CG  1 
ATOM   2261 C CD1 . TYR   B 2 103 ? 118.118 121.035 100.282 1.00 54.36  ? 85  TYR   C CD1 1 
ATOM   2262 C CD2 . TYR   B 2 103 ? 118.504 119.160 98.891  1.00 54.36  ? 85  TYR   C CD2 1 
ATOM   2263 C CE1 . TYR   B 2 103 ? 117.358 121.611 99.287  1.00 54.36  ? 85  TYR   C CE1 1 
ATOM   2264 C CE2 . TYR   B 2 103 ? 117.750 119.727 97.897  1.00 54.36  ? 85  TYR   C CE2 1 
ATOM   2265 C CZ  . TYR   B 2 103 ? 117.177 120.948 98.098  1.00 54.36  ? 85  TYR   C CZ  1 
ATOM   2266 O OH  . TYR   B 2 103 ? 116.419 121.509 97.100  1.00 54.36  ? 85  TYR   C OH  1 
ATOM   2267 N N   . THR   B 2 104 ? 121.824 119.293 103.645 1.00 51.88  ? 86  THR   C N   1 
ATOM   2268 C CA  . THR   B 2 104 ? 122.568 118.411 104.527 1.00 51.88  ? 86  THR   C CA  1 
ATOM   2269 C C   . THR   B 2 104 ? 123.374 119.131 105.600 1.00 51.88  ? 86  THR   C C   1 
ATOM   2270 O O   . THR   B 2 104 ? 123.945 118.455 106.462 1.00 51.88  ? 86  THR   C O   1 
ATOM   2271 C CB  . THR   B 2 104 ? 123.522 117.522 103.715 1.00 51.88  ? 86  THR   C CB  1 
ATOM   2272 O OG1 . THR   B 2 104 ? 124.507 118.339 103.072 1.00 51.88  ? 86  THR   C OG1 1 
ATOM   2273 C CG2 . THR   B 2 104 ? 122.776 116.750 102.659 1.00 51.88  ? 86  THR   C CG2 1 
ATOM   2274 N N   . THR   B 2 105 ? 123.467 120.465 105.548 1.00 52.30  ? 87  THR   C N   1 
ATOM   2275 C CA  . THR   B 2 105 ? 124.242 121.309 106.460 1.00 52.30  ? 87  THR   C CA  1 
ATOM   2276 C C   . THR   B 2 105 ? 125.736 121.193 106.157 1.00 52.30  ? 87  THR   C C   1 
ATOM   2277 O O   . THR   B 2 105 ? 126.555 121.930 106.713 1.00 52.30  ? 87  THR   C O   1 
ATOM   2278 C CB  . THR   B 2 105 ? 123.926 120.959 107.923 1.00 52.30  ? 87  THR   C CB  1 
ATOM   2279 O OG1 . THR   B 2 105 ? 122.532 121.163 108.161 1.00 52.30  ? 87  THR   C OG1 1 
ATOM   2280 C CG2 . THR   B 2 105 ? 124.685 121.845 108.906 1.00 52.30  ? 87  THR   C CG2 1 
ATOM   2281 N N   . ASN   B 2 106 ? 126.098 120.313 105.231 1.00 49.55  ? 88  ASN   C N   1 
ATOM   2282 C CA  . ASN   B 2 106 ? 127.502 120.068 104.936 1.00 49.55  ? 88  ASN   C CA  1 
ATOM   2283 C C   . ASN   B 2 106 ? 128.165 121.302 104.342 1.00 49.55  ? 88  ASN   C C   1 
ATOM   2284 O O   . ASN   B 2 106 ? 127.537 122.099 103.645 1.00 49.55  ? 88  ASN   C O   1 
ATOM   2285 C CB  . ASN   B 2 106 ? 127.643 118.900 103.969 1.00 49.55  ? 88  ASN   C CB  1 
ATOM   2286 C CG  . ASN   B 2 106 ? 127.598 117.573 104.660 1.00 49.55  ? 88  ASN   C CG  1 
ATOM   2287 O OD1 . ASN   B 2 106 ? 127.597 117.499 105.885 1.00 49.55  ? 88  ASN   C OD1 1 
ATOM   2288 N ND2 . ASN   B 2 106 ? 127.554 116.506 103.880 1.00 49.55  ? 88  ASN   C ND2 1 
ATOM   2289 N N   . LYS   B 2 107 ? 129.454 121.449 104.625 1.00 48.45  ? 89  LYS   C N   1 
ATOM   2290 C CA  . LYS   B 2 107 ? 130.277 122.494 104.042 1.00 48.45  ? 89  LYS   C CA  1 
ATOM   2291 C C   . LYS   B 2 107 ? 131.058 121.950 102.859 1.00 48.45  ? 89  LYS   C C   1 
ATOM   2292 O O   . LYS   B 2 107 ? 131.642 120.869 102.928 1.00 48.45  ? 89  LYS   C O   1 
ATOM   2293 C CB  . LYS   B 2 107 ? 131.247 123.066 105.065 1.00 48.45  ? 89  LYS   C CB  1 
ATOM   2294 C CG  . LYS   B 2 107 ? 130.610 123.438 106.345 1.00 48.45  ? 89  LYS   C CG  1 
ATOM   2295 C CD  . LYS   B 2 107 ? 131.570 124.180 107.215 1.00 48.45  ? 89  LYS   C CD  1 
ATOM   2296 C CE  . LYS   B 2 107 ? 130.912 124.496 108.521 1.00 48.45  ? 89  LYS   C CE  1 
ATOM   2297 N NZ  . LYS   B 2 107 ? 130.471 123.239 109.172 1.00 48.45  ? 89  LYS   C NZ  1 
ATOM   2298 N N   . VAL   B 2 108 ? 131.071 122.717 101.778 1.00 46.91  ? 90  VAL   C N   1 
ATOM   2299 C CA  . VAL   B 2 108 ? 131.693 122.306 100.534 1.00 46.91  ? 90  VAL   C CA  1 
ATOM   2300 C C   . VAL   B 2 108 ? 133.070 122.929 100.360 1.00 46.91  ? 90  VAL   C C   1 
ATOM   2301 O O   . VAL   B 2 108 ? 134.013 122.247 99.961  1.00 46.91  ? 90  VAL   C O   1 
ATOM   2302 C CB  . VAL   B 2 108 ? 130.761 122.655 99.355  1.00 46.91  ? 90  VAL   C CB  1 
ATOM   2303 C CG1 . VAL   B 2 108 ? 131.344 122.193 98.056  1.00 46.91  ? 90  VAL   C CG1 1 
ATOM   2304 C CG2 . VAL   B 2 108 ? 129.409 122.048 99.567  1.00 46.91  ? 90  VAL   C CG2 1 
ATOM   2305 N N   . HIS   B 2 109 ? 133.210 124.216 100.661 1.00 46.56  ? 91  HIS   C N   1 
ATOM   2306 C CA  . HIS   B 2 109 ? 134.488 124.901 100.577 1.00 46.56  ? 91  HIS   C CA  1 
ATOM   2307 C C   . HIS   B 2 109 ? 134.616 125.851 101.755 1.00 46.56  ? 91  HIS   C C   1 
ATOM   2308 O O   . HIS   B 2 109 ? 133.639 126.164 102.434 1.00 46.56  ? 91  HIS   C O   1 
ATOM   2309 C CB  . HIS   B 2 109 ? 134.640 125.686 99.269  1.00 46.56  ? 91  HIS   C CB  1 
ATOM   2310 C CG  . HIS   B 2 109 ? 134.609 124.838 98.040  1.00 46.56  ? 91  HIS   C CG  1 
ATOM   2311 N ND1 . HIS   B 2 109 ? 133.502 124.752 97.228  1.00 46.56  ? 91  HIS   C ND1 1 
ATOM   2312 C CD2 . HIS   B 2 109 ? 135.551 124.049 97.476  1.00 46.56  ? 91  HIS   C CD2 1 
ATOM   2313 C CE1 . HIS   B 2 109 ? 133.760 123.942 96.220  1.00 46.56  ? 91  HIS   C CE1 1 
ATOM   2314 N NE2 . HIS   B 2 109 ? 134.997 123.501 96.347  1.00 46.56  ? 91  HIS   C NE2 1 
ATOM   2315 N N   . ALA   B 2 110 ? 135.841 126.311 101.987 1.00 48.74  ? 92  ALA   C N   1 
ATOM   2316 C CA  . ALA   B 2 110 ? 136.133 127.338 102.989 1.00 48.74  ? 92  ALA   C CA  1 
ATOM   2317 C C   . ALA   B 2 110 ? 137.273 128.190 102.437 1.00 48.74  ? 92  ALA   C C   1 
ATOM   2318 O O   . ALA   B 2 110 ? 138.448 127.855 102.593 1.00 48.74  ? 92  ALA   C O   1 
ATOM   2319 C CB  . ALA   B 2 110 ? 136.484 126.720 104.332 1.00 48.74  ? 92  ALA   C CB  1 
ATOM   2320 N N   . ILE   B 2 111 ? 136.916 129.292 101.791 1.00 51.03  ? 93  ILE   C N   1 
ATOM   2321 C CA  . ILE   B 2 111 ? 137.896 130.171 101.168 1.00 51.03  ? 93  ILE   C CA  1 
ATOM   2322 C C   . ILE   B 2 111 ? 138.468 131.114 102.217 1.00 51.03  ? 93  ILE   C C   1 
ATOM   2323 O O   . ILE   B 2 111 ? 137.718 131.882 102.835 1.00 51.03  ? 93  ILE   C O   1 
ATOM   2324 C CB  . ILE   B 2 111 ? 137.280 130.956 100.006 1.00 51.03  ? 93  ILE   C CB  1 
ATOM   2325 C CG1 . ILE   B 2 111 ? 136.398 130.046 99.164  1.00 51.03  ? 93  ILE   C CG1 1 
ATOM   2326 C CG2 . ILE   B 2 111 ? 138.367 131.564 99.155  1.00 51.03  ? 93  ILE   C CG2 1 
ATOM   2327 C CD1 . ILE   B 2 111 ? 135.605 130.768 98.111  1.00 51.03  ? 93  ILE   C CD1 1 
ATOM   2328 N N   . PRO   B 2 112 ? 139.780 131.092 102.454 1.00 53.66  ? 94  PRO   C N   1 
ATOM   2329 C CA  . PRO   B 2 112 ? 140.384 132.035 103.401 1.00 53.66  ? 94  PRO   C CA  1 
ATOM   2330 C C   . PRO   B 2 112 ? 140.678 133.358 102.709 1.00 53.66  ? 94  PRO   C C   1 
ATOM   2331 O O   . PRO   B 2 112 ? 141.475 133.420 101.771 1.00 53.66  ? 94  PRO   C O   1 
ATOM   2332 C CB  . PRO   B 2 112 ? 141.668 131.321 103.834 1.00 53.66  ? 94  PRO   C CB  1 
ATOM   2333 C CG  . PRO   B 2 112 ? 142.017 130.456 102.682 1.00 53.66  ? 94  PRO   C CG  1 
ATOM   2334 C CD  . PRO   B 2 112 ? 140.764 130.138 101.919 1.00 53.66  ? 94  PRO   C CD  1 
ATOM   2335 N N   . LEU   B 2 113 ? 140.024 134.417 103.175 1.00 53.94  ? 95  LEU   C N   1 
ATOM   2336 C CA  . LEU   B 2 113 ? 140.134 135.725 102.555 1.00 53.94  ? 95  LEU   C CA  1 
ATOM   2337 C C   . LEU   B 2 113 ? 141.427 136.421 102.960 1.00 53.94  ? 95  LEU   C C   1 
ATOM   2338 O O   . LEU   B 2 113 ? 141.968 136.195 104.046 1.00 53.94  ? 95  LEU   C O   1 
ATOM   2339 C CB  . LEU   B 2 113 ? 138.943 136.595 102.942 1.00 53.94  ? 95  LEU   C CB  1 
ATOM   2340 C CG  . LEU   B 2 113 ? 137.565 136.080 102.554 1.00 53.94  ? 95  LEU   C CG  1 
ATOM   2341 C CD1 . LEU   B 2 113 ? 136.521 136.694 103.440 1.00 53.94  ? 95  LEU   C CD1 1 
ATOM   2342 C CD2 . LEU   B 2 113 ? 137.285 136.400 101.112 1.00 53.94  ? 95  LEU   C CD2 1 
ATOM   2343 N N   . ARG   B 2 114 ? 141.922 137.280 102.068 1.00 55.69  ? 96  ARG   C N   1 
ATOM   2344 C CA  . ARG   B 2 114 ? 143.112 138.063 102.373 1.00 55.69  ? 96  ARG   C CA  1 
ATOM   2345 C C   . ARG   B 2 114 ? 142.792 139.215 103.315 1.00 55.69  ? 96  ARG   C C   1 
ATOM   2346 O O   . ARG   B 2 114 ? 143.611 139.567 104.171 1.00 55.69  ? 96  ARG   C O   1 
ATOM   2347 C CB  . ARG   B 2 114 ? 143.747 138.584 101.084 1.00 55.69  ? 96  ARG   C CB  1 
ATOM   2348 N N   . SER   B 2 115 ? 141.614 139.810 103.172 1.00 55.00  ? 97  SER   C N   1 
ATOM   2349 C CA  . SER   B 2 115 ? 141.133 140.856 104.062 1.00 55.00  ? 97  SER   C CA  1 
ATOM   2350 C C   . SER   B 2 115 ? 139.904 140.347 104.795 1.00 55.00  ? 97  SER   C C   1 
ATOM   2351 O O   . SER   B 2 115 ? 139.016 139.747 104.182 1.00 55.00  ? 97  SER   C O   1 
ATOM   2352 C CB  . SER   B 2 115 ? 140.800 142.128 103.284 1.00 55.00  ? 97  SER   C CB  1 
ATOM   2353 N N   . SER   B 2 116 ? 139.851 140.586 106.097 1.00 53.78  ? 98  SER   C N   1 
ATOM   2354 C CA  . SER   B 2 116 ? 138.811 140.019 106.938 1.00 53.78  ? 98  SER   C CA  1 
ATOM   2355 C C   . SER   B 2 116 ? 137.556 140.874 107.012 1.00 53.78  ? 98  SER   C C   1 
ATOM   2356 O O   . SER   B 2 116 ? 136.616 140.500 107.719 1.00 53.78  ? 98  SER   C O   1 
ATOM   2357 C CB  . SER   B 2 116 ? 139.352 139.788 108.348 1.00 53.78  ? 98  SER   C CB  1 
ATOM   2358 O OG  . SER   B 2 116 ? 140.568 139.064 108.310 1.00 53.78  ? 98  SER   C OG  1 
ATOM   2359 N N   . TRP   B 2 117 ? 137.511 142.001 106.317 1.00 52.85  ? 99  TRP   C N   1 
ATOM   2360 C CA  . TRP   B 2 117 ? 136.400 142.945 106.400 1.00 52.85  ? 99  TRP   C CA  1 
ATOM   2361 C C   . TRP   B 2 117 ? 135.621 142.879 105.090 1.00 52.85  ? 99  TRP   C C   1 
ATOM   2362 O O   . TRP   B 2 117 ? 135.884 143.636 104.156 1.00 52.85  ? 99  TRP   C O   1 
ATOM   2363 C CB  . TRP   B 2 117 ? 136.911 144.351 106.684 1.00 52.85  ? 99  TRP   C CB  1 
ATOM   2364 C CG  . TRP   B 2 117 ? 138.030 144.369 107.660 1.00 52.85  ? 99  TRP   C CG  1 
ATOM   2365 C CD1 . TRP   B 2 117 ? 139.356 144.320 107.377 1.00 52.85  ? 99  TRP   C CD1 1 
ATOM   2366 C CD2 . TRP   B 2 117 ? 137.925 144.419 109.082 1.00 52.85  ? 99  TRP   C CD2 1 
ATOM   2367 N NE1 . TRP   B 2 117 ? 140.087 144.341 108.535 1.00 52.85  ? 99  TRP   C NE1 1 
ATOM   2368 C CE2 . TRP   B 2 117 ? 139.226 144.400 109.596 1.00 52.85  ? 99  TRP   C CE2 1 
ATOM   2369 C CE3 . TRP   B 2 117 ? 136.853 144.481 109.973 1.00 52.85  ? 99  TRP   C CE3 1 
ATOM   2370 C CZ2 . TRP   B 2 117 ? 139.486 144.441 110.958 1.00 52.85  ? 99  TRP   C CZ2 1 
ATOM   2371 C CZ3 . TRP   B 2 117 ? 137.112 144.514 111.318 1.00 52.85  ? 99  TRP   C CZ3 1 
ATOM   2372 C CH2 . TRP   B 2 117 ? 138.415 144.497 111.801 1.00 52.85  ? 99  TRP   C CH2 1 
ATOM   2373 N N   . VAL   B 2 118 ? 134.654 141.973 105.030 1.00 52.05  ? 100 VAL   C N   1 
ATOM   2374 C CA  . VAL   B 2 118 ? 133.848 141.748 103.840 1.00 52.05  ? 100 VAL   C CA  1 
ATOM   2375 C C   . VAL   B 2 118 ? 132.414 142.148 104.131 1.00 52.05  ? 100 VAL   C C   1 
ATOM   2376 O O   . VAL   B 2 118 ? 131.889 141.881 105.216 1.00 52.05  ? 100 VAL   C O   1 
ATOM   2377 C CB  . VAL   B 2 118 ? 133.927 140.288 103.360 1.00 52.05  ? 100 VAL   C CB  1 
ATOM   2378 C CG1 . VAL   B 2 118 ? 135.327 139.968 102.953 1.00 52.05  ? 100 VAL   C CG1 1 
ATOM   2379 C CG2 . VAL   B 2 118 ? 133.500 139.350 104.457 1.00 52.05  ? 100 VAL   C CG2 1 
ATOM   2380 N N   . MET   B 2 119 ? 131.787 142.806 103.161 1.00 54.94  ? 101 MET   C N   1 
ATOM   2381 C CA  . MET   B 2 119 ? 130.409 143.252 103.282 1.00 54.94  ? 101 MET   C CA  1 
ATOM   2382 C C   . MET   B 2 119 ? 129.519 142.734 102.164 1.00 54.94  ? 101 MET   C C   1 
ATOM   2383 O O   . MET   B 2 119 ? 128.358 143.145 102.076 1.00 54.94  ? 101 MET   C O   1 
ATOM   2384 C CB  . MET   B 2 119 ? 130.354 144.778 103.318 1.00 54.94  ? 101 MET   C CB  1 
ATOM   2385 C CG  . MET   B 2 119 ? 131.120 145.388 104.463 1.00 54.94  ? 101 MET   C CG  1 
ATOM   2386 S SD  . MET   B 2 119 ? 131.150 147.178 104.344 1.00 54.94  ? 101 MET   C SD  1 
ATOM   2387 C CE  . MET   B 2 119 ? 132.028 147.365 102.802 1.00 54.94  ? 101 MET   C CE  1 
ATOM   2388 N N   . THR   B 2 120 ? 130.019 141.849 101.309 1.00 52.99  ? 102 THR   C N   1 
ATOM   2389 C CA  . THR   B 2 120 ? 129.244 141.436 100.153 1.00 52.99  ? 102 THR   C CA  1 
ATOM   2390 C C   . THR   B 2 120 ? 129.649 140.042 99.706  1.00 52.99  ? 102 THR   C C   1 
ATOM   2391 O O   . THR   B 2 120 ? 130.789 139.615 99.888  1.00 52.99  ? 102 THR   C O   1 
ATOM   2392 C CB  . THR   B 2 120 ? 129.402 142.427 98.997  1.00 52.99  ? 102 THR   C CB  1 
ATOM   2393 O OG1 . THR   B 2 120 ? 128.500 142.082 97.939  1.00 52.99  ? 102 THR   C OG1 1 
ATOM   2394 C CG2 . THR   B 2 120 ? 130.823 142.428 98.475  1.00 52.99  ? 102 THR   C CG2 1 
ATOM   2395 N N   . CYS   B 2 121 ? 128.681 139.335 99.133  1.00 50.26  ? 103 CYS   C N   1 
ATOM   2396 C CA  . CYS   B 2 121 ? 128.881 138.050 98.488  1.00 50.26  ? 103 CYS   C CA  1 
ATOM   2397 C C   . CYS   B 2 121 ? 128.205 138.073 97.130  1.00 50.26  ? 103 CYS   C C   1 
ATOM   2398 O O   . CYS   B 2 121 ? 127.279 138.849 96.886  1.00 50.26  ? 103 CYS   C O   1 
ATOM   2399 C CB  . CYS   B 2 121 ? 128.308 136.895 99.300  1.00 50.26  ? 103 CYS   C CB  1 
ATOM   2400 S SG  . CYS   B 2 121 ? 129.274 136.396 100.679 1.00 50.26  ? 103 CYS   C SG  1 
ATOM   2401 N N   . ALA   B 2 122 ? 128.670 137.202 96.249  1.00 46.64  ? 104 ALA   C N   1 
ATOM   2402 C CA  . ALA   B 2 122 ? 128.071 137.071 94.930  1.00 46.64  ? 104 ALA   C CA  1 
ATOM   2403 C C   . ALA   B 2 122 ? 128.386 135.686 94.405  1.00 46.64  ? 104 ALA   C C   1 
ATOM   2404 O O   . ALA   B 2 122 ? 129.555 135.345 94.225  1.00 46.64  ? 104 ALA   C O   1 
ATOM   2405 C CB  . ALA   B 2 122 ? 128.589 138.139 93.980  1.00 46.64  ? 104 ALA   C CB  1 
ATOM   2406 N N   . TYR   B 2 123 ? 127.348 134.902 94.160  1.00 47.97  ? 105 TYR   C N   1 
ATOM   2407 C CA  . TYR   B 2 123 ? 127.466 133.575 93.588  1.00 47.97  ? 105 TYR   C CA  1 
ATOM   2408 C C   . TYR   B 2 123 ? 127.122 133.687 92.112  1.00 47.97  ? 105 TYR   C C   1 
ATOM   2409 O O   . TYR   B 2 123 ? 126.073 134.233 91.761  1.00 47.97  ? 105 TYR   C O   1 
ATOM   2410 C CB  . TYR   B 2 123 ? 126.498 132.618 94.274  1.00 47.97  ? 105 TYR   C CB  1 
ATOM   2411 C CG  . TYR   B 2 123 ? 126.869 131.168 94.207  1.00 47.97  ? 105 TYR   C CG  1 
ATOM   2412 C CD1 . TYR   B 2 123 ? 127.584 130.586 95.232  1.00 47.97  ? 105 TYR   C CD1 1 
ATOM   2413 C CD2 . TYR   B 2 123 ? 126.544 130.388 93.116  1.00 47.97  ? 105 TYR   C CD2 1 
ATOM   2414 C CE1 . TYR   B 2 123 ? 127.930 129.271 95.198  1.00 47.97  ? 105 TYR   C CE1 1 
ATOM   2415 C CE2 . TYR   B 2 123 ? 126.902 129.062 93.070  1.00 47.97  ? 105 TYR   C CE2 1 
ATOM   2416 C CZ  . TYR   B 2 123 ? 127.600 128.515 94.121  1.00 47.97  ? 105 TYR   C CZ  1 
ATOM   2417 O OH  . TYR   B 2 123 ? 127.963 127.191 94.088  1.00 47.97  ? 105 TYR   C OH  1 
ATOM   2418 N N   . ALA   B 2 124 ? 127.997 133.191 91.253  1.00 50.96  ? 106 ALA   C N   1 
ATOM   2419 C CA  . ALA   B 2 124 ? 127.730 133.273 89.829  1.00 50.96  ? 106 ALA   C CA  1 
ATOM   2420 C C   . ALA   B 2 124 ? 126.502 132.437 89.482  1.00 50.96  ? 106 ALA   C C   1 
ATOM   2421 O O   . ALA   B 2 124 ? 126.277 131.384 90.085  1.00 50.96  ? 106 ALA   C O   1 
ATOM   2422 C CB  . ALA   B 2 124 ? 128.930 132.790 89.027  1.00 50.96  ? 106 ALA   C CB  1 
ATOM   2423 N N   . PRO   B 2 125 ? 125.679 132.885 88.532  1.00 54.47  ? 107 PRO   C N   1 
ATOM   2424 C CA  . PRO   B 2 125 ? 124.532 132.064 88.126  1.00 54.47  ? 107 PRO   C CA  1 
ATOM   2425 C C   . PRO   B 2 125 ? 124.938 130.716 87.565  1.00 54.47  ? 107 PRO   C C   1 
ATOM   2426 O O   . PRO   B 2 125 ? 124.210 129.733 87.747  1.00 54.47  ? 107 PRO   C O   1 
ATOM   2427 C CB  . PRO   B 2 125 ? 123.831 132.936 87.075  1.00 54.47  ? 107 PRO   C CB  1 
ATOM   2428 C CG  . PRO   B 2 125 ? 124.340 134.311 87.311  1.00 54.47  ? 107 PRO   C CG  1 
ATOM   2429 C CD  . PRO   B 2 125 ? 125.741 134.147 87.787  1.00 54.47  ? 107 PRO   C CD  1 
ATOM   2430 N N   . SER   B 2 126 ? 126.086 130.640 86.886  1.00 57.93  ? 108 SER   C N   1 
ATOM   2431 C CA  . SER   B 2 126 ? 126.589 129.358 86.409  1.00 57.93  ? 108 SER   C CA  1 
ATOM   2432 C C   . SER   B 2 126 ? 127.071 128.480 87.554  1.00 57.93  ? 108 SER   C C   1 
ATOM   2433 O O   . SER   B 2 126 ? 126.968 127.252 87.479  1.00 57.93  ? 108 SER   C O   1 
ATOM   2434 C CB  . SER   B 2 126 ? 127.719 129.579 85.406  1.00 57.93  ? 108 SER   C CB  1 
ATOM   2435 O OG  . SER   B 2 126 ? 128.714 130.432 85.942  1.00 57.93  ? 108 SER   C OG  1 
ATOM   2436 N N   . GLY   B 2 127 ? 127.601 129.084 88.611  1.00 56.94  ? 109 GLY   C N   1 
ATOM   2437 C CA  . GLY   B 2 127 ? 128.088 128.355 89.758  1.00 56.94  ? 109 GLY   C CA  1 
ATOM   2438 C C   . GLY   B 2 127 ? 129.584 128.164 89.809  1.00 56.94  ? 109 GLY   C C   1 
ATOM   2439 O O   . GLY   B 2 127 ? 130.077 127.543 90.755  1.00 56.94  ? 109 GLY   C O   1 
ATOM   2440 N N   . ASN   B 2 128 ? 130.320 128.675 88.828  1.00 58.94  ? 110 ASN   C N   1 
ATOM   2441 C CA  . ASN   B 2 128 ? 131.756 128.464 88.781  1.00 58.94  ? 110 ASN   C CA  1 
ATOM   2442 C C   . ASN   B 2 128 ? 132.531 129.466 89.622  1.00 58.94  ? 110 ASN   C C   1 
ATOM   2443 O O   . ASN   B 2 128 ? 133.658 129.169 90.028  1.00 58.94  ? 110 ASN   C O   1 
ATOM   2444 C CB  . ASN   B 2 128 ? 132.246 128.528 87.333  1.00 58.94  ? 110 ASN   C CB  1 
ATOM   2445 C CG  . ASN   B 2 128 ? 131.421 127.667 86.398  1.00 58.94  ? 110 ASN   C CG  1 
ATOM   2446 O OD1 . ASN   B 2 128 ? 131.032 126.553 86.744  1.00 58.94  ? 110 ASN   C OD1 1 
ATOM   2447 N ND2 . ASN   B 2 128 ? 131.149 128.180 85.207  1.00 58.94  ? 110 ASN   C ND2 1 
ATOM   2448 N N   . TYR   B 2 129 ? 131.963 130.633 89.895  1.00 54.53  ? 111 TYR   C N   1 
ATOM   2449 C CA  . TYR   B 2 129 ? 132.680 131.711 90.554  1.00 54.53  ? 111 TYR   C CA  1 
ATOM   2450 C C   . TYR   B 2 129 ? 131.902 132.196 91.763  1.00 54.53  ? 111 TYR   C C   1 
ATOM   2451 O O   . TYR   B 2 129 ? 130.680 132.066 91.827  1.00 54.53  ? 111 TYR   C O   1 
ATOM   2452 C CB  . TYR   B 2 129 ? 132.916 132.887 89.607  1.00 54.53  ? 111 TYR   C CB  1 
ATOM   2453 C CG  . TYR   B 2 129 ? 133.802 132.575 88.436  1.00 54.53  ? 111 TYR   C CG  1 
ATOM   2454 C CD1 . TYR   B 2 129 ? 135.150 132.862 88.473  1.00 54.53  ? 111 TYR   C CD1 1 
ATOM   2455 C CD2 . TYR   B 2 129 ? 133.293 132.000 87.290  1.00 54.53  ? 111 TYR   C CD2 1 
ATOM   2456 C CE1 . TYR   B 2 129 ? 135.968 132.579 87.406  1.00 54.53  ? 111 TYR   C CE1 1 
ATOM   2457 C CE2 . TYR   B 2 129 ? 134.104 131.709 86.219  1.00 54.53  ? 111 TYR   C CE2 1 
ATOM   2458 C CZ  . TYR   B 2 129 ? 135.441 132.000 86.283  1.00 54.53  ? 111 TYR   C CZ  1 
ATOM   2459 O OH  . TYR   B 2 129 ? 136.255 131.717 85.212  1.00 54.53  ? 111 TYR   C OH  1 
ATOM   2460 N N   . VAL   B 2 130 ? 132.630 132.747 92.731  1.00 49.97  ? 112 VAL   C N   1 
ATOM   2461 C CA  . VAL   B 2 130 ? 132.054 133.562 93.787  1.00 49.97  ? 112 VAL   C CA  1 
ATOM   2462 C C   . VAL   B 2 130 ? 132.880 134.833 93.877  1.00 49.97  ? 112 VAL   C C   1 
ATOM   2463 O O   . VAL   B 2 130 ? 134.038 134.878 93.463  1.00 49.97  ? 112 VAL   C O   1 
ATOM   2464 C CB  . VAL   B 2 130 ? 132.000 132.854 95.157  1.00 49.97  ? 112 VAL   C CB  1 
ATOM   2465 C CG1 . VAL   B 2 130 ? 131.074 131.678 95.098  1.00 49.97  ? 112 VAL   C CG1 1 
ATOM   2466 C CG2 . VAL   B 2 130 ? 133.372 132.421 95.593  1.00 49.97  ? 112 VAL   C CG2 1 
ATOM   2467 N N   . ALA   B 2 131 ? 132.262 135.880 94.409  1.00 50.92  ? 113 ALA   C N   1 
ATOM   2468 C CA  . ALA   B 2 131 ? 132.905 137.175 94.551  1.00 50.92  ? 113 ALA   C CA  1 
ATOM   2469 C C   . ALA   B 2 131 ? 132.802 137.651 95.991  1.00 50.92  ? 113 ALA   C C   1 
ATOM   2470 O O   . ALA   B 2 131 ? 131.883 137.280 96.721  1.00 50.92  ? 113 ALA   C O   1 
ATOM   2471 C CB  . ALA   B 2 131 ? 132.285 138.209 93.619  1.00 50.92  ? 113 ALA   C CB  1 
ATOM   2472 N N   . CYS   B 2 132 ? 133.766 138.470 96.394  1.00 56.53  ? 114 CYS   C N   1 
ATOM   2473 C CA  . CYS   B 2 132 ? 133.761 139.091 97.706  1.00 56.53  ? 114 CYS   C CA  1 
ATOM   2474 C C   . CYS   B 2 132 ? 134.298 140.505 97.571  1.00 56.53  ? 114 CYS   C C   1 
ATOM   2475 O O   . CYS   B 2 132 ? 134.974 140.842 96.599  1.00 56.53  ? 114 CYS   C O   1 
ATOM   2476 C CB  . CYS   B 2 132 ? 134.622 138.335 98.712  1.00 56.53  ? 114 CYS   C CB  1 
ATOM   2477 S SG  . CYS   B 2 132 ? 136.370 138.351 98.290  1.00 56.53  ? 114 CYS   C SG  1 
ATOM   2478 N N   . GLY   B 2 133 ? 133.992 141.330 98.560  1.00 54.32  ? 115 GLY   C N   1 
ATOM   2479 C CA  . GLY   B 2 133 ? 134.521 142.676 98.591  1.00 54.32  ? 115 GLY   C CA  1 
ATOM   2480 C C   . GLY   B 2 133 ? 134.178 143.352 99.893  1.00 54.32  ? 115 GLY   C C   1 
ATOM   2481 O O   . GLY   B 2 133 ? 133.313 142.893 100.644 1.00 54.32  ? 115 GLY   C O   1 
ATOM   2482 N N   . GLY   B 2 134 ? 134.867 144.452 100.152 1.00 53.24  ? 116 GLY   C N   1 
ATOM   2483 C CA  . GLY   B 2 134 ? 134.614 145.200 101.361 1.00 53.24  ? 116 GLY   C CA  1 
ATOM   2484 C C   . GLY   B 2 134 ? 135.449 146.448 101.529 1.00 53.24  ? 116 GLY   C C   1 
ATOM   2485 O O   . GLY   B 2 134 ? 135.615 147.231 100.595 1.00 53.24  ? 116 GLY   C O   1 
ATOM   2486 N N   . LEU   B 2 135 ? 135.972 146.643 102.738 1.00 53.30  ? 117 LEU   C N   1 
ATOM   2487 C CA  . LEU   B 2 135 ? 136.680 147.864 103.085 1.00 53.30  ? 117 LEU   C CA  1 
ATOM   2488 C C   . LEU   B 2 135 ? 138.037 147.975 102.413 1.00 53.30  ? 117 LEU   C C   1 
ATOM   2489 O O   . LEU   B 2 135 ? 138.651 149.042 102.477 1.00 53.30  ? 117 LEU   C O   1 
ATOM   2490 C CB  . LEU   B 2 135 ? 136.832 147.954 104.599 1.00 53.30  ? 117 LEU   C CB  1 
ATOM   2491 C CG  . LEU   B 2 135 ? 135.542 148.141 105.383 1.00 53.30  ? 117 LEU   C CG  1 
ATOM   2492 C CD1 . LEU   B 2 135 ? 135.783 148.034 106.868 1.00 53.30  ? 117 LEU   C CD1 1 
ATOM   2493 C CD2 . LEU   B 2 135 ? 134.950 149.483 105.043 1.00 53.30  ? 117 LEU   C CD2 1 
ATOM   2494 N N   . ASP   B 2 136 ? 138.510 146.920 101.769 1.00 56.59  ? 118 ASP   C N   1 
ATOM   2495 C CA  . ASP   B 2 136 ? 139.805 146.925 101.117 1.00 56.59  ? 118 ASP   C CA  1 
ATOM   2496 C C   . ASP   B 2 136 ? 139.746 147.430 99.684  1.00 56.59  ? 118 ASP   C C   1 
ATOM   2497 O O   . ASP   B 2 136 ? 140.728 147.282 98.950  1.00 56.59  ? 118 ASP   C O   1 
ATOM   2498 C CB  . ASP   B 2 136 ? 140.417 145.525 101.164 1.00 56.59  ? 118 ASP   C CB  1 
ATOM   2499 C CG  . ASP   B 2 136 ? 139.591 144.492 100.410 1.00 56.59  ? 118 ASP   C CG  1 
ATOM   2500 O OD1 . ASP   B 2 136 ? 138.515 144.839 99.879  1.00 56.59  ? 118 ASP   C OD1 1 
ATOM   2501 O OD2 . ASP   B 2 136 ? 140.025 143.323 100.347 1.00 56.59  ? 118 ASP   C OD2 1 
ATOM   2502 N N   . ASN   B 2 137 ? 138.614 147.992 99.265  1.00 56.39  ? 119 ASN   C N   1 
ATOM   2503 C CA  . ASN   B 2 137 ? 138.422 148.658 97.980  1.00 56.39  ? 119 ASN   C CA  1 
ATOM   2504 C C   . ASN   B 2 137 ? 138.467 147.716 96.783  1.00 56.39  ? 119 ASN   C C   1 
ATOM   2505 O O   . ASN   B 2 137 ? 138.471 148.192 95.643  1.00 56.39  ? 119 ASN   C O   1 
ATOM   2506 C CB  . ASN   B 2 137 ? 139.462 149.762 97.761  1.00 56.39  ? 119 ASN   C CB  1 
ATOM   2507 C CG  . ASN   B 2 137 ? 139.184 150.994 98.579  1.00 56.39  ? 119 ASN   C CG  1 
ATOM   2508 O OD1 . ASN   B 2 137 ? 138.062 151.471 98.631  1.00 56.39  ? 119 ASN   C OD1 1 
ATOM   2509 N ND2 . ASN   B 2 137 ? 140.215 151.522 99.224  1.00 56.39  ? 119 ASN   C ND2 1 
ATOM   2510 N N   . ILE   B 2 138 ? 138.500 146.402 96.991  1.00 56.89  ? 120 ILE   C N   1 
ATOM   2511 C CA  . ILE   B 2 138 ? 138.793 145.448 95.927  1.00 56.89  ? 120 ILE   C CA  1 
ATOM   2512 C C   . ILE   B 2 138 ? 137.704 144.388 95.871  1.00 56.89  ? 120 ILE   C C   1 
ATOM   2513 O O   . ILE   B 2 138 ? 137.218 143.926 96.908  1.00 56.89  ? 120 ILE   C O   1 
ATOM   2514 C CB  . ILE   B 2 138 ? 140.174 144.788 96.130  1.00 56.89  ? 120 ILE   C CB  1 
ATOM   2515 C CG1 . ILE   B 2 138 ? 141.289 145.804 95.927  1.00 56.89  ? 120 ILE   C CG1 1 
ATOM   2516 C CG2 . ILE   B 2 138 ? 140.373 143.626 95.179  1.00 56.89  ? 120 ILE   C CG2 1 
ATOM   2517 C CD1 . ILE   B 2 138 ? 142.660 145.194 95.929  1.00 56.89  ? 120 ILE   C CD1 1 
ATOM   2518 N N   . CYS   B 2 139 ? 137.319 144.011 94.655  1.00 56.94  ? 121 CYS   C N   1 
ATOM   2519 C CA  . CYS   B 2 139 ? 136.482 142.845 94.405  1.00 56.94  ? 121 CYS   C CA  1 
ATOM   2520 C C   . CYS   B 2 139 ? 137.383 141.687 93.992  1.00 56.94  ? 121 CYS   C C   1 
ATOM   2521 O O   . CYS   B 2 139 ? 138.158 141.813 93.038  1.00 56.94  ? 121 CYS   C O   1 
ATOM   2522 C CB  . CYS   B 2 139 ? 135.456 143.136 93.313  1.00 56.94  ? 121 CYS   C CB  1 
ATOM   2523 S SG  . CYS   B 2 139 ? 134.058 142.019 93.280  1.00 56.94  ? 121 CYS   C SG  1 
ATOM   2524 N N   . SER   B 2 140 ? 137.285 140.570 94.702  1.00 55.54  ? 122 SER   C N   1 
ATOM   2525 C CA  . SER   B 2 140 ? 138.072 139.380 94.407  1.00 55.54  ? 122 SER   C CA  1 
ATOM   2526 C C   . SER   B 2 140 ? 137.149 138.270 93.928  1.00 55.54  ? 122 SER   C C   1 
ATOM   2527 O O   . SER   B 2 140 ? 136.183 137.923 94.613  1.00 55.54  ? 122 SER   C O   1 
ATOM   2528 C CB  . SER   B 2 140 ? 138.852 138.927 95.638  1.00 55.54  ? 122 SER   C CB  1 
ATOM   2529 O OG  . SER   B 2 140 ? 139.652 139.977 96.147  1.00 55.54  ? 122 SER   C OG  1 
ATOM   2530 N N   . ILE   B 2 141 ? 137.440 137.726 92.754  1.00 53.14  ? 123 ILE   C N   1 
ATOM   2531 C CA  . ILE   B 2 141 ? 136.645 136.666 92.151  1.00 53.14  ? 123 ILE   C CA  1 
ATOM   2532 C C   . ILE   B 2 141 ? 137.379 135.351 92.352  1.00 53.14  ? 123 ILE   C C   1 
ATOM   2533 O O   . ILE   B 2 141 ? 138.562 135.236 92.013  1.00 53.14  ? 123 ILE   C O   1 
ATOM   2534 C CB  . ILE   B 2 141 ? 136.400 136.933 90.658  1.00 53.14  ? 123 ILE   C CB  1 
ATOM   2535 C CG1 . ILE   B 2 141 ? 135.935 138.365 90.436  1.00 53.14  ? 123 ILE   C CG1 1 
ATOM   2536 C CG2 . ILE   B 2 141 ? 135.371 135.977 90.113  1.00 53.14  ? 123 ILE   C CG2 1 
ATOM   2537 C CD1 . ILE   B 2 141 ? 134.528 138.619 90.862  1.00 53.14  ? 123 ILE   C CD1 1 
ATOM   2538 N N   . TYR   B 2 142 ? 136.687 134.360 92.901  1.00 52.84  ? 124 TYR   C N   1 
ATOM   2539 C CA  . TYR   B 2 142 ? 137.280 133.073 93.228  1.00 52.84  ? 124 TYR   C CA  1 
ATOM   2540 C C   . TYR   B 2 142 ? 136.775 132.003 92.274  1.00 52.84  ? 124 TYR   C C   1 
ATOM   2541 O O   . TYR   B 2 142 ? 135.575 131.918 92.010  1.00 52.84  ? 124 TYR   C O   1 
ATOM   2542 C CB  . TYR   B 2 142 ? 136.966 132.682 94.666  1.00 52.84  ? 124 TYR   C CB  1 
ATOM   2543 C CG  . TYR   B 2 142 ? 137.561 133.599 95.687  1.00 52.84  ? 124 TYR   C CG  1 
ATOM   2544 C CD1 . TYR   B 2 142 ? 136.832 134.640 96.212  1.00 52.84  ? 124 TYR   C CD1 1 
ATOM   2545 C CD2 . TYR   B 2 142 ? 138.850 133.415 96.134  1.00 52.84  ? 124 TYR   C CD2 1 
ATOM   2546 C CE1 . TYR   B 2 142 ? 137.366 135.466 97.145  1.00 52.84  ? 124 TYR   C CE1 1 
ATOM   2547 C CE2 . TYR   B 2 142 ? 139.395 134.239 97.069  1.00 52.84  ? 124 TYR   C CE2 1 
ATOM   2548 C CZ  . TYR   B 2 142 ? 138.649 135.267 97.575  1.00 52.84  ? 124 TYR   C CZ  1 
ATOM   2549 O OH  . TYR   B 2 142 ? 139.197 136.105 98.517  1.00 52.84  ? 124 TYR   C OH  1 
ATOM   2550 N N   . ASN   B 2 143 ? 137.696 131.195 91.761  1.00 58.21  ? 125 ASN   C N   1 
ATOM   2551 C CA  . ASN   B 2 143 ? 137.388 130.098 90.857  1.00 58.21  ? 125 ASN   C CA  1 
ATOM   2552 C C   . ASN   B 2 143 ? 137.153 128.837 91.674  1.00 58.21  ? 125 ASN   C C   1 
ATOM   2553 O O   . ASN   B 2 143 ? 138.028 128.418 92.437  1.00 58.21  ? 125 ASN   C O   1 
ATOM   2554 C CB  . ASN   B 2 143 ? 138.539 129.889 89.880  1.00 58.21  ? 125 ASN   C CB  1 
ATOM   2555 C CG  . ASN   B 2 143 ? 138.087 129.360 88.548  1.00 58.21  ? 125 ASN   C CG  1 
ATOM   2556 O OD1 . ASN   B 2 143 ? 136.901 129.360 88.237  1.00 58.21  ? 125 ASN   C OD1 1 
ATOM   2557 N ND2 . ASN   B 2 143 ? 139.035 128.912 87.743  1.00 58.21  ? 125 ASN   C ND2 1 
ATOM   2558 N N   . LEU   B 2 144 ? 135.978 128.233 91.520  1.00 59.11  ? 126 LEU   C N   1 
ATOM   2559 C CA  . LEU   B 2 144 ? 135.597 127.080 92.326  1.00 59.11  ? 126 LEU   C CA  1 
ATOM   2560 C C   . LEU   B 2 144 ? 135.811 125.766 91.584  1.00 59.11  ? 126 LEU   C C   1 
ATOM   2561 O O   . LEU   B 2 144 ? 136.511 124.879 92.075  1.00 59.11  ? 126 LEU   C O   1 
ATOM   2562 C CB  . LEU   B 2 144 ? 134.136 127.214 92.769  1.00 59.11  ? 126 LEU   C CB  1 
ATOM   2563 C CG  . LEU   B 2 144 ? 133.762 128.457 93.568  1.00 59.11  ? 126 LEU   C CG  1 
ATOM   2564 C CD1 . LEU   B 2 144 ? 132.284 128.471 93.817  1.00 59.11  ? 126 LEU   C CD1 1 
ATOM   2565 C CD2 . LEU   B 2 144 ? 134.506 128.481 94.870  1.00 59.11  ? 126 LEU   C CD2 1 
ATOM   2566 N N   . LYS   B 2 145 ? 135.210 125.621 90.406  1.00 67.84  ? 127 LYS   C N   1 
ATOM   2567 C CA  . LYS   B 2 145 ? 135.332 124.393 89.624  1.00 67.84  ? 127 LYS   C CA  1 
ATOM   2568 C C   . LYS   B 2 145 ? 136.637 124.450 88.846  1.00 67.84  ? 127 LYS   C C   1 
ATOM   2569 O O   . LYS   B 2 145 ? 136.685 124.864 87.688  1.00 67.84  ? 127 LYS   C O   1 
ATOM   2570 C CB  . LYS   B 2 145 ? 134.136 124.212 88.700  1.00 67.84  ? 127 LYS   C CB  1 
ATOM   2571 C CG  . LYS   B 2 145 ? 132.820 124.012 89.427  1.00 67.84  ? 127 LYS   C CG  1 
ATOM   2572 C CD  . LYS   B 2 145 ? 131.695 123.708 88.455  1.00 67.84  ? 127 LYS   C CD  1 
ATOM   2573 C CE  . LYS   B 2 145 ? 130.349 123.678 89.160  1.00 67.84  ? 127 LYS   C CE  1 
ATOM   2574 N NZ  . LYS   B 2 145 ? 129.613 122.410 88.895  1.00 67.84  ? 127 LYS   C NZ  1 
ATOM   2575 N N   . THR   B 2 146 ? 137.712 124.027 89.500  1.00 71.46  ? 128 THR   C N   1 
ATOM   2576 C CA  . THR   B 2 146 ? 139.022 123.949 88.880  1.00 71.46  ? 128 THR   C CA  1 
ATOM   2577 C C   . THR   B 2 146 ? 139.669 122.632 89.277  1.00 71.46  ? 128 THR   C C   1 
ATOM   2578 O O   . THR   B 2 146 ? 139.185 121.915 90.157  1.00 71.46  ? 128 THR   C O   1 
ATOM   2579 C CB  . THR   B 2 146 ? 139.914 125.125 89.289  1.00 71.46  ? 128 THR   C CB  1 
ATOM   2580 O OG1 . THR   B 2 146 ? 141.184 125.012 88.636  1.00 71.46  ? 128 THR   C OG1 1 
ATOM   2581 C CG2 . THR   B 2 146 ? 140.125 125.130 90.789  1.00 71.46  ? 128 THR   C CG2 1 
ATOM   2582 N N   . ARG   B 2 147 ? 140.777 122.316 88.617  1.00 74.21  ? 129 ARG   C N   1 
ATOM   2583 C CA  . ARG   B 2 147 ? 141.611 121.196 89.026  1.00 74.21  ? 129 ARG   C CA  1 
ATOM   2584 C C   . ARG   B 2 147 ? 142.446 121.640 90.223  1.00 74.21  ? 129 ARG   C C   1 
ATOM   2585 O O   . ARG   B 2 147 ? 142.130 122.624 90.896  1.00 74.21  ? 129 ARG   C O   1 
ATOM   2586 C CB  . ARG   B 2 147 ? 142.465 120.706 87.863  1.00 74.21  ? 129 ARG   C CB  1 
ATOM   2587 C CG  . ARG   B 2 147 ? 141.680 120.466 86.586  1.00 74.21  ? 129 ARG   C CG  1 
ATOM   2588 C CD  . ARG   B 2 147 ? 142.488 119.663 85.582  1.00 74.21  ? 129 ARG   C CD  1 
ATOM   2589 N NE  . ARG   B 2 147 ? 142.490 118.238 85.897  1.00 74.21  ? 129 ARG   C NE  1 
ATOM   2590 C CZ  . ARG   B 2 147 ? 143.271 117.343 85.301  1.00 74.21  ? 129 ARG   C CZ  1 
ATOM   2591 N NH1 . ARG   B 2 147 ? 144.117 117.725 84.355  1.00 74.21  ? 129 ARG   C NH1 1 
ATOM   2592 N NH2 . ARG   B 2 147 ? 143.206 116.066 85.651  1.00 74.21  ? 129 ARG   C NH2 1 
ATOM   2593 N N   . GLU   B 2 148 ? 143.478 120.865 90.545  1.00 72.37  ? 130 GLU   C N   1 
ATOM   2594 C CA  . GLU   B 2 148 ? 144.420 121.111 91.637  1.00 72.37  ? 130 GLU   C CA  1 
ATOM   2595 C C   . GLU   B 2 148 ? 143.726 121.264 92.990  1.00 72.37  ? 130 GLU   C C   1 
ATOM   2596 O O   . GLU   B 2 148 ? 144.372 121.597 93.986  1.00 72.37  ? 130 GLU   C O   1 
ATOM   2597 C CB  . GLU   B 2 148 ? 145.328 122.320 91.348  1.00 72.37  ? 130 GLU   C CB  1 
ATOM   2598 C CG  . GLU   B 2 148 ? 144.761 123.713 91.566  1.00 72.37  ? 130 GLU   C CG  1 
ATOM   2599 C CD  . GLU   B 2 148 ? 144.414 124.415 90.265  1.00 72.37  ? 130 GLU   C CD  1 
ATOM   2600 O OE1 . GLU   B 2 148 ? 144.412 123.749 89.209  1.00 72.37  ? 130 GLU   C OE1 1 
ATOM   2601 O OE2 . GLU   B 2 148 ? 144.141 125.633 90.301  1.00 72.37  ? 130 GLU   C OE2 1 
ATOM   2602 N N   . GLY   B 2 149 ? 142.422 121.003 93.038  1.00 70.28  ? 131 GLY   C N   1 
ATOM   2603 C CA  . GLY   B 2 149 ? 141.709 120.812 94.288  1.00 70.28  ? 131 GLY   C CA  1 
ATOM   2604 C C   . GLY   B 2 149 ? 141.706 121.985 95.239  1.00 70.28  ? 131 GLY   C C   1 
ATOM   2605 O O   . GLY   B 2 149 ? 141.414 121.806 96.423  1.00 70.28  ? 131 GLY   C O   1 
ATOM   2606 N N   . ASN   B 2 150 ? 142.020 123.184 94.763  1.00 70.11  ? 132 ASN   C N   1 
ATOM   2607 C CA  . ASN   B 2 150 ? 142.072 124.363 95.612  1.00 70.11  ? 132 ASN   C CA  1 
ATOM   2608 C C   . ASN   B 2 150 ? 141.294 125.491 94.957  1.00 70.11  ? 132 ASN   C C   1 
ATOM   2609 O O   . ASN   B 2 150 ? 141.428 125.724 93.752  1.00 70.11  ? 132 ASN   C O   1 
ATOM   2610 C CB  . ASN   B 2 150 ? 143.518 124.798 95.866  1.00 70.11  ? 132 ASN   C CB  1 
ATOM   2611 C CG  . ASN   B 2 150 ? 144.119 124.136 97.088  1.00 70.11  ? 132 ASN   C CG  1 
ATOM   2612 O OD1 . ASN   B 2 150 ? 143.432 123.895 98.081  1.00 70.11  ? 132 ASN   C OD1 1 
ATOM   2613 N ND2 . ASN   B 2 150 ? 145.412 123.838 97.024  1.00 70.11  ? 132 ASN   C ND2 1 
ATOM   2614 N N   . VAL   B 2 151 ? 140.483 126.184 95.747  1.00 61.75  ? 133 VAL   C N   1 
ATOM   2615 C CA  . VAL   B 2 151 ? 139.805 127.386 95.281  1.00 61.75  ? 133 VAL   C CA  1 
ATOM   2616 C C   . VAL   B 2 151 ? 140.802 128.534 95.327  1.00 61.75  ? 133 VAL   C C   1 
ATOM   2617 O O   . VAL   B 2 151 ? 141.373 128.827 96.381  1.00 61.75  ? 133 VAL   C O   1 
ATOM   2618 C CB  . VAL   B 2 151 ? 138.569 127.690 96.135  1.00 61.75  ? 133 VAL   C CB  1 
ATOM   2619 C CG1 . VAL   B 2 151 ? 138.039 129.078 95.824  1.00 61.75  ? 133 VAL   C CG1 1 
ATOM   2620 C CG2 . VAL   B 2 151 ? 137.501 126.643 95.910  1.00 61.75  ? 133 VAL   C CG2 1 
ATOM   2621 N N   . ARG   B 2 152 ? 141.022 129.181 94.188  1.00 62.98  ? 134 ARG   C N   1 
ATOM   2622 C CA  . ARG   B 2 152 ? 142.029 130.221 94.084  1.00 62.98  ? 134 ARG   C CA  1 
ATOM   2623 C C   . ARG   B 2 152 ? 141.435 131.461 93.444  1.00 62.98  ? 134 ARG   C C   1 
ATOM   2624 O O   . ARG   B 2 152 ? 140.351 131.430 92.857  1.00 62.98  ? 134 ARG   C O   1 
ATOM   2625 C CB  . ARG   B 2 152 ? 143.248 129.764 93.280  1.00 62.98  ? 134 ARG   C CB  1 
ATOM   2626 C CG  . ARG   B 2 152 ? 142.970 129.472 91.827  1.00 62.98  ? 134 ARG   C CG  1 
ATOM   2627 C CD  . ARG   B 2 152 ? 144.246 129.065 91.111  1.00 62.98  ? 134 ARG   C CD  1 
ATOM   2628 N NE  . ARG   B 2 152 ? 143.999 128.695 89.721  1.00 62.98  ? 134 ARG   C NE  1 
ATOM   2629 C CZ  . ARG   B 2 152 ? 143.989 129.556 88.710  1.00 62.98  ? 134 ARG   C CZ  1 
ATOM   2630 N NH1 . ARG   B 2 152 ? 143.756 129.130 87.476  1.00 62.98  ? 134 ARG   C NH1 1 
ATOM   2631 N NH2 . ARG   B 2 152 ? 144.214 130.844 88.931  1.00 62.98  ? 134 ARG   C NH2 1 
ATOM   2632 N N   . VAL   B 2 153 ? 142.170 132.562 93.565  1.00 58.32  ? 135 VAL   C N   1 
ATOM   2633 C CA  . VAL   B 2 153 ? 141.680 133.846 93.092  1.00 58.32  ? 135 VAL   C CA  1 
ATOM   2634 C C   . VAL   B 2 153 ? 141.819 133.912 91.580  1.00 58.32  ? 135 VAL   C C   1 
ATOM   2635 O O   . VAL   B 2 153 ? 142.901 133.681 91.028  1.00 58.32  ? 135 VAL   C O   1 
ATOM   2636 C CB  . VAL   B 2 153 ? 142.437 134.992 93.773  1.00 58.32  ? 135 VAL   C CB  1 
ATOM   2637 C CG1 . VAL   B 2 153 ? 141.978 136.318 93.222  1.00 58.32  ? 135 VAL   C CG1 1 
ATOM   2638 C CG2 . VAL   B 2 153 ? 142.226 134.939 95.265  1.00 58.32  ? 135 VAL   C CG2 1 
ATOM   2639 N N   . SER   B 2 154 ? 140.718 134.227 90.904  1.00 58.75  ? 136 SER   C N   1 
ATOM   2640 C CA  . SER   B 2 154 ? 140.754 134.384 89.459  1.00 58.75  ? 136 SER   C CA  1 
ATOM   2641 C C   . SER   B 2 154 ? 141.330 135.737 89.066  1.00 58.75  ? 136 SER   C C   1 
ATOM   2642 O O   . SER   B 2 154 ? 142.252 135.812 88.248  1.00 58.75  ? 136 SER   C O   1 
ATOM   2643 C CB  . SER   B 2 154 ? 139.351 134.215 88.879  1.00 58.75  ? 136 SER   C CB  1 
ATOM   2644 O OG  . SER   B 2 154 ? 138.996 132.849 88.793  1.00 58.75  ? 136 SER   C OG  1 
ATOM   2645 N N   . ARG   B 2 155 ? 140.798 136.815 89.637  1.00 60.56  ? 137 ARG   C N   1 
ATOM   2646 C CA  . ARG   B 2 155 ? 141.259 138.152 89.301  1.00 60.56  ? 137 ARG   C CA  1 
ATOM   2647 C C   . ARG   B 2 155 ? 140.800 139.129 90.370  1.00 60.56  ? 137 ARG   C C   1 
ATOM   2648 O O   . ARG   B 2 155 ? 139.677 139.033 90.861  1.00 60.56  ? 137 ARG   C O   1 
ATOM   2649 C CB  . ARG   B 2 155 ? 140.742 138.589 87.931  1.00 60.56  ? 137 ARG   C CB  1 
ATOM   2650 C CG  . ARG   B 2 155 ? 141.537 139.729 87.326  1.00 60.56  ? 137 ARG   C CG  1 
ATOM   2651 C CD  . ARG   B 2 155 ? 140.960 140.152 85.997  1.00 60.56  ? 137 ARG   C CD  1 
ATOM   2652 N NE  . ARG   B 2 155 ? 140.901 139.040 85.056  1.00 60.56  ? 137 ARG   C NE  1 
ATOM   2653 C CZ  . ARG   B 2 155 ? 141.895 138.697 84.244  1.00 60.56  ? 137 ARG   C CZ  1 
ATOM   2654 N NH1 . ARG   B 2 155 ? 141.753 137.670 83.419  1.00 60.56  ? 137 ARG   C NH1 1 
ATOM   2655 N NH2 . ARG   B 2 155 ? 143.030 139.382 84.256  1.00 60.56  ? 137 ARG   C NH2 1 
ATOM   2656 N N   . GLU   B 2 156 ? 141.674 140.067 90.716  1.00 60.09  ? 138 GLU   C N   1 
ATOM   2657 C CA  . GLU   B 2 156 ? 141.358 141.142 91.646  1.00 60.09  ? 138 GLU   C CA  1 
ATOM   2658 C C   . GLU   B 2 156 ? 140.985 142.389 90.856  1.00 60.09  ? 138 GLU   C C   1 
ATOM   2659 O O   . GLU   B 2 156 ? 141.708 142.785 89.938  1.00 60.09  ? 138 GLU   C O   1 
ATOM   2660 C CB  . GLU   B 2 156 ? 142.539 141.432 92.568  1.00 60.09  ? 138 GLU   C CB  1 
ATOM   2661 C CG  . GLU   B 2 156 ? 142.560 140.587 93.821  1.00 60.09  ? 138 GLU   C CG  1 
ATOM   2662 C CD  . GLU   B 2 156 ? 143.945 140.472 94.423  1.00 60.09  ? 138 GLU   C CD  1 
ATOM   2663 O OE1 . GLU   B 2 156 ? 144.899 141.021 93.832  1.00 60.09  ? 138 GLU   C OE1 1 
ATOM   2664 O OE2 . GLU   B 2 156 ? 144.081 139.832 95.486  1.00 60.09  ? 138 GLU   C OE2 1 
ATOM   2665 N N   . LEU   B 2 157 ? 139.867 143.005 91.216  1.00 57.02  ? 139 LEU   C N   1 
ATOM   2666 C CA  . LEU   B 2 157 ? 139.279 144.092 90.441  1.00 57.02  ? 139 LEU   C CA  1 
ATOM   2667 C C   . LEU   B 2 157 ? 139.429 145.398 91.215  1.00 57.02  ? 139 LEU   C C   1 
ATOM   2668 O O   . LEU   B 2 157 ? 138.578 145.755 92.030  1.00 57.02  ? 139 LEU   C O   1 
ATOM   2669 C CB  . LEU   B 2 157 ? 137.825 143.795 90.130  1.00 57.02  ? 139 LEU   C CB  1 
ATOM   2670 C CG  . LEU   B 2 157 ? 137.553 142.502 89.367  1.00 57.02  ? 139 LEU   C CG  1 
ATOM   2671 C CD1 . LEU   B 2 157 ? 136.134 142.461 88.880  1.00 57.02  ? 139 LEU   C CD1 1 
ATOM   2672 C CD2 . LEU   B 2 157 ? 138.518 142.356 88.202  1.00 57.02  ? 139 LEU   C CD2 1 
ATOM   2673 N N   . ALA   B 2 158 ? 140.512 146.116 90.943  1.00 57.75  ? 140 ALA   C N   1 
ATOM   2674 C CA  . ALA   B 2 158 ? 140.743 147.430 91.520  1.00 57.75  ? 140 ALA   C CA  1 
ATOM   2675 C C   . ALA   B 2 158 ? 140.134 148.512 90.637  1.00 57.75  ? 140 ALA   C C   1 
ATOM   2676 O O   . ALA   B 2 158 ? 139.920 148.320 89.439  1.00 57.75  ? 140 ALA   C O   1 
ATOM   2677 C CB  . ALA   B 2 158 ? 142.236 147.684 91.702  1.00 57.75  ? 140 ALA   C CB  1 
ATOM   2678 N N   . GLY   B 2 159 ? 139.864 149.665 91.240  1.00 54.32  ? 141 GLY   C N   1 
ATOM   2679 C CA  . GLY   B 2 159 ? 139.282 150.753 90.481  1.00 54.32  ? 141 GLY   C CA  1 
ATOM   2680 C C   . GLY   B 2 159 ? 138.300 151.638 91.221  1.00 54.32  ? 141 GLY   C C   1 
ATOM   2681 O O   . GLY   B 2 159 ? 137.875 152.666 90.691  1.00 54.32  ? 141 GLY   C O   1 
ATOM   2682 N N   . HIS   B 2 160 ? 137.926 151.261 92.431  1.00 50.66  ? 142 HIS   C N   1 
ATOM   2683 C CA  . HIS   B 2 160 ? 137.106 152.107 93.280  1.00 50.66  ? 142 HIS   C CA  1 
ATOM   2684 C C   . HIS   B 2 160 ? 137.990 152.871 94.253  1.00 50.66  ? 142 HIS   C C   1 
ATOM   2685 O O   . HIS   B 2 160 ? 139.162 152.543 94.455  1.00 50.66  ? 142 HIS   C O   1 
ATOM   2686 C CB  . HIS   B 2 160 ? 136.079 151.275 94.053  1.00 50.66  ? 142 HIS   C CB  1 
ATOM   2687 C CG  . HIS   B 2 160 ? 134.852 150.933 93.264  1.00 50.66  ? 142 HIS   C CG  1 
ATOM   2688 N ND1 . HIS   B 2 160 ? 133.985 151.890 92.785  1.00 50.66  ? 142 HIS   C ND1 1 
ATOM   2689 C CD2 . HIS   B 2 160 ? 134.348 149.741 92.873  1.00 50.66  ? 142 HIS   C CD2 1 
ATOM   2690 C CE1 . HIS   B 2 160 ? 133.002 151.302 92.131  1.00 50.66  ? 142 HIS   C CE1 1 
ATOM   2691 N NE2 . HIS   B 2 160 ? 133.199 149.999 92.169  1.00 50.66  ? 142 HIS   C NE2 1 
ATOM   2692 N N   . THR   B 2 161 ? 137.415 153.905 94.861  1.00 50.87  ? 143 THR   C N   1 
ATOM   2693 C CA  . THR   B 2 161 ? 138.084 154.648 95.920  1.00 50.87  ? 143 THR   C CA  1 
ATOM   2694 C C   . THR   B 2 161 ? 137.284 154.616 97.215  1.00 50.87  ? 143 THR   C C   1 
ATOM   2695 O O   . THR   B 2 161 ? 137.447 155.495 98.065  1.00 50.87  ? 143 THR   C O   1 
ATOM   2696 C CB  . THR   B 2 161 ? 138.345 156.090 95.487  1.00 50.87  ? 143 THR   C CB  1 
ATOM   2697 O OG1 . THR   B 2 161 ? 137.123 156.686 95.039  1.00 50.87  ? 143 THR   C OG1 1 
ATOM   2698 C CG2 . THR   B 2 161 ? 139.365 156.131 94.359  1.00 50.87  ? 143 THR   C CG2 1 
ATOM   2699 N N   . GLY   B 2 162 ? 136.416 153.620 97.380  1.00 49.05  ? 144 GLY   C N   1 
ATOM   2700 C CA  . GLY   B 2 162 ? 135.615 153.501 98.578  1.00 49.05  ? 144 GLY   C CA  1 
ATOM   2701 C C   . GLY   B 2 162 ? 135.231 152.061 98.815  1.00 49.05  ? 144 GLY   C C   1 
ATOM   2702 O O   . GLY   B 2 162 ? 135.456 151.188 97.978  1.00 49.05  ? 144 GLY   C O   1 
ATOM   2703 N N   . TYR   B 2 163 ? 134.640 151.824 99.979  1.00 50.50  ? 145 TYR   C N   1 
ATOM   2704 C CA  . TYR   B 2 163 ? 134.242 150.480 100.359 1.00 50.50  ? 145 TYR   C CA  1 
ATOM   2705 C C   . TYR   B 2 163 ? 133.207 149.941 99.385  1.00 50.50  ? 145 TYR   C C   1 
ATOM   2706 O O   . TYR   B 2 163 ? 132.246 150.629 99.036  1.00 50.50  ? 145 TYR   C O   1 
ATOM   2707 C CB  . TYR   B 2 163 ? 133.698 150.477 101.790 1.00 50.50  ? 145 TYR   C CB  1 
ATOM   2708 C CG  . TYR   B 2 163 ? 132.437 151.271 101.992 1.00 50.50  ? 145 TYR   C CG  1 
ATOM   2709 C CD1 . TYR   B 2 163 ? 132.466 152.644 102.080 1.00 50.50  ? 145 TYR   C CD1 1 
ATOM   2710 C CD2 . TYR   B 2 163 ? 131.217 150.645 102.080 1.00 50.50  ? 145 TYR   C CD2 1 
ATOM   2711 C CE1 . TYR   B 2 163 ? 131.320 153.368 102.252 1.00 50.50  ? 145 TYR   C CE1 1 
ATOM   2712 C CE2 . TYR   B 2 163 ? 130.062 151.359 102.252 1.00 50.50  ? 145 TYR   C CE2 1 
ATOM   2713 C CZ  . TYR   B 2 163 ? 130.118 152.721 102.339 1.00 50.50  ? 145 TYR   C CZ  1 
ATOM   2714 O OH  . TYR   B 2 163 ? 128.962 153.445 102.516 1.00 50.50  ? 145 TYR   C OH  1 
ATOM   2715 N N   . LEU   B 2 164 ? 133.420 148.712 98.932  1.00 49.81  ? 146 LEU   C N   1 
ATOM   2716 C CA  . LEU   B 2 164 ? 132.503 148.052 98.016  1.00 49.81  ? 146 LEU   C CA  1 
ATOM   2717 C C   . LEU   B 2 164 ? 131.289 147.553 98.784  1.00 49.81  ? 146 LEU   C C   1 
ATOM   2718 O O   . LEU   B 2 164 ? 131.408 146.671 99.637  1.00 49.81  ? 146 LEU   C O   1 
ATOM   2719 C CB  . LEU   B 2 164 ? 133.199 146.891 97.322  1.00 49.81  ? 146 LEU   C CB  1 
ATOM   2720 C CG  . LEU   B 2 164 ? 133.735 147.100 95.921  1.00 49.81  ? 146 LEU   C CG  1 
ATOM   2721 C CD1 . LEU   B 2 164 ? 134.869 148.091 95.930  1.00 49.81  ? 146 LEU   C CD1 1 
ATOM   2722 C CD2 . LEU   B 2 164 ? 134.183 145.777 95.365  1.00 49.81  ? 146 LEU   C CD2 1 
ATOM   2723 N N   . SER   B 2 165 ? 130.118 148.101 98.474  1.00 49.64  ? 147 SER   C N   1 
ATOM   2724 C CA  . SER   B 2 165 ? 128.910 147.718 99.192  1.00 49.64  ? 147 SER   C CA  1 
ATOM   2725 C C   . SER   B 2 165 ? 128.326 146.423 98.645  1.00 49.64  ? 147 SER   C C   1 
ATOM   2726 O O   . SER   B 2 165 ? 128.206 145.432 99.368  1.00 49.64  ? 147 SER   C O   1 
ATOM   2727 C CB  . SER   B 2 165 ? 127.886 148.845 99.115  1.00 49.64  ? 147 SER   C CB  1 
ATOM   2728 O OG  . SER   B 2 165 ? 128.480 150.087 99.439  1.00 49.64  ? 147 SER   C OG  1 
ATOM   2729 N N   . CYS   B 2 166 ? 127.955 146.413 97.372  1.00 49.17  ? 148 CYS   C N   1 
ATOM   2730 C CA  . CYS   B 2 166 ? 127.283 145.277 96.767  1.00 49.17  ? 148 CYS   C CA  1 
ATOM   2731 C C   . CYS   B 2 166 ? 127.965 144.911 95.465  1.00 49.17  ? 148 CYS   C C   1 
ATOM   2732 O O   . CYS   B 2 166 ? 128.480 145.776 94.757  1.00 49.17  ? 148 CYS   C O   1 
ATOM   2733 C CB  . CYS   B 2 166 ? 125.810 145.576 96.510  1.00 49.17  ? 148 CYS   C CB  1 
ATOM   2734 S SG  . CYS   B 2 166 ? 124.874 144.199 95.824  1.00 49.17  ? 148 CYS   C SG  1 
ATOM   2735 N N   . CYS   B 2 167 ? 127.981 143.618 95.169  1.00 47.36  ? 149 CYS   C N   1 
ATOM   2736 C CA  . CYS   B 2 167 ? 128.480 143.096 93.909  1.00 47.36  ? 149 CYS   C CA  1 
ATOM   2737 C C   . CYS   B 2 167 ? 127.509 142.046 93.402  1.00 47.36  ? 149 CYS   C C   1 
ATOM   2738 O O   . CYS   B 2 167 ? 127.203 141.086 94.114  1.00 47.36  ? 149 CYS   C O   1 
ATOM   2739 C CB  . CYS   B 2 167 ? 129.884 142.506 94.065  1.00 47.36  ? 149 CYS   C CB  1 
ATOM   2740 S SG  . CYS   B 2 167 ? 130.052 141.179 95.255  1.00 47.36  ? 149 CYS   C SG  1 
ATOM   2741 N N   . ARG   B 2 168 ? 127.014 142.234 92.187  1.00 46.35  ? 150 ARG   C N   1 
ATOM   2742 C CA  . ARG   B 2 168 ? 126.129 141.276 91.551  1.00 46.35  ? 150 ARG   C CA  1 
ATOM   2743 C C   . ARG   B 2 168 ? 126.720 140.835 90.223  1.00 46.35  ? 150 ARG   C C   1 
ATOM   2744 O O   . ARG   B 2 168 ? 127.440 141.586 89.564  1.00 46.35  ? 150 ARG   C O   1 
ATOM   2745 C CB  . ARG   B 2 168 ? 124.738 141.855 91.330  1.00 46.35  ? 150 ARG   C CB  1 
ATOM   2746 C CG  . ARG   B 2 168 ? 123.994 142.141 92.601  1.00 46.35  ? 150 ARG   C CG  1 
ATOM   2747 C CD  . ARG   B 2 168 ? 124.040 140.955 93.527  1.00 46.35  ? 150 ARG   C CD  1 
ATOM   2748 N NE  . ARG   B 2 168 ? 123.128 141.109 94.653  1.00 46.35  ? 150 ARG   C NE  1 
ATOM   2749 C CZ  . ARG   B 2 168 ? 123.339 140.591 95.855  1.00 46.35  ? 150 ARG   C CZ  1 
ATOM   2750 N NH1 . ARG   B 2 168 ? 124.434 139.887 96.087  1.00 46.35  ? 150 ARG   C NH1 1 
ATOM   2751 N NH2 . ARG   B 2 168 ? 122.459 140.778 96.827  1.00 46.35  ? 150 ARG   C NH2 1 
ATOM   2752 N N   . PHE   B 2 169 ? 126.406 139.609 89.837  1.00 47.41  ? 151 PHE   C N   1 
ATOM   2753 C CA  . PHE   B 2 169 ? 126.897 139.016 88.605  1.00 47.41  ? 151 PHE   C CA  1 
ATOM   2754 C C   . PHE   B 2 169 ? 125.832 139.159 87.527  1.00 47.41  ? 151 PHE   C C   1 
ATOM   2755 O O   . PHE   B 2 169 ? 124.742 138.592 87.650  1.00 47.41  ? 151 PHE   C O   1 
ATOM   2756 C CB  . PHE   B 2 169 ? 127.215 137.540 88.812  1.00 47.41  ? 151 PHE   C CB  1 
ATOM   2757 C CG  . PHE   B 2 169 ? 128.639 137.247 89.155  1.00 47.41  ? 151 PHE   C CG  1 
ATOM   2758 C CD1 . PHE   B 2 169 ? 129.615 137.280 88.197  1.00 47.41  ? 151 PHE   C CD1 1 
ATOM   2759 C CD2 . PHE   B 2 169 ? 128.981 136.855 90.431  1.00 47.41  ? 151 PHE   C CD2 1 
ATOM   2760 C CE1 . PHE   B 2 169 ? 130.907 136.971 88.518  1.00 47.41  ? 151 PHE   C CE1 1 
ATOM   2761 C CE2 . PHE   B 2 169 ? 130.259 136.548 90.748  1.00 47.41  ? 151 PHE   C CE2 1 
ATOM   2762 C CZ  . PHE   B 2 169 ? 131.227 136.604 89.792  1.00 47.41  ? 151 PHE   C CZ  1 
ATOM   2763 N N   . LEU   B 2 170 ? 126.136 139.920 86.479  1.00 53.15  ? 152 LEU   C N   1 
ATOM   2764 C CA  . LEU   B 2 170 ? 125.266 139.924 85.310  1.00 53.15  ? 152 LEU   C CA  1 
ATOM   2765 C C   . LEU   B 2 170 ? 125.344 138.596 84.572  1.00 53.15  ? 152 LEU   C C   1 
ATOM   2766 O O   . LEU   B 2 170 ? 124.324 138.058 84.131  1.00 53.15  ? 152 LEU   C O   1 
ATOM   2767 C CB  . LEU   B 2 170 ? 125.655 141.057 84.369  1.00 53.15  ? 152 LEU   C CB  1 
ATOM   2768 C CG  . LEU   B 2 170 ? 125.425 142.501 84.779  1.00 53.15  ? 152 LEU   C CG  1 
ATOM   2769 C CD1 . LEU   B 2 170 ? 125.600 143.386 83.570  1.00 53.15  ? 152 LEU   C CD1 1 
ATOM   2770 C CD2 . LEU   B 2 170 ? 124.052 142.673 85.361  1.00 53.15  ? 152 LEU   C CD2 1 
ATOM   2771 N N   . ASP   B 2 171 ? 126.547 138.059 84.430  1.00 59.51  ? 153 ASP   C N   1 
ATOM   2772 C CA  . ASP   B 2 171 ? 126.806 136.859 83.653  1.00 59.51  ? 153 ASP   C CA  1 
ATOM   2773 C C   . ASP   B 2 171 ? 128.155 136.321 84.119  1.00 59.51  ? 153 ASP   C C   1 
ATOM   2774 O O   . ASP   B 2 171 ? 128.698 136.769 85.134  1.00 59.51  ? 153 ASP   C O   1 
ATOM   2775 C CB  . ASP   B 2 171 ? 126.757 137.174 82.153  1.00 59.51  ? 153 ASP   C CB  1 
ATOM   2776 C CG  . ASP   B 2 171 ? 126.807 135.929 81.280  1.00 59.51  ? 153 ASP   C CG  1 
ATOM   2777 O OD1 . ASP   B 2 171 ? 126.911 134.813 81.832  1.00 59.51  ? 153 ASP   C OD1 1 
ATOM   2778 O OD2 . ASP   B 2 171 ? 126.743 136.069 80.041  1.00 59.51  ? 153 ASP   C OD2 1 
ATOM   2779 N N   . ASP   B 2 172 ? 128.704 135.360 83.380  1.00 62.40  ? 154 ASP   C N   1 
ATOM   2780 C CA  . ASP   B 2 172 ? 129.946 134.726 83.804  1.00 62.40  ? 154 ASP   C CA  1 
ATOM   2781 C C   . ASP   B 2 172 ? 131.137 135.673 83.716  1.00 62.40  ? 154 ASP   C C   1 
ATOM   2782 O O   . ASP   B 2 172 ? 132.097 135.520 84.475  1.00 62.40  ? 154 ASP   C O   1 
ATOM   2783 C CB  . ASP   B 2 172 ? 130.204 133.475 82.963  1.00 62.40  ? 154 ASP   C CB  1 
ATOM   2784 C CG  . ASP   B 2 172 ? 131.101 132.478 83.666  1.00 62.40  ? 154 ASP   C CG  1 
ATOM   2785 O OD1 . ASP   B 2 172 ? 131.426 132.704 84.850  1.00 62.40  ? 154 ASP   C OD1 1 
ATOM   2786 O OD2 . ASP   B 2 172 ? 131.481 131.469 83.036  1.00 62.40  ? 154 ASP   C OD2 1 
ATOM   2787 N N   . ASN   B 2 173 ? 131.105 136.641 82.807  1.00 60.77  ? 155 ASN   C N   1 
ATOM   2788 C CA  . ASN   B 2 173 ? 132.220 137.559 82.604  1.00 60.77  ? 155 ASN   C CA  1 
ATOM   2789 C C   . ASN   B 2 173 ? 131.771 139.011 82.698  1.00 60.77  ? 155 ASN   C C   1 
ATOM   2790 O O   . ASN   B 2 173 ? 132.253 139.880 81.968  1.00 60.77  ? 155 ASN   C O   1 
ATOM   2791 C CB  . ASN   B 2 173 ? 132.917 137.285 81.273  1.00 60.77  ? 155 ASN   C CB  1 
ATOM   2792 C CG  . ASN   B 2 173 ? 132.018 137.523 80.068  1.00 60.77  ? 155 ASN   C CG  1 
ATOM   2793 O OD1 . ASN   B 2 173 ? 130.895 138.012 80.189  1.00 60.77  ? 155 ASN   C OD1 1 
ATOM   2794 N ND2 . ASN   B 2 173 ? 132.518 137.172 78.889  1.00 60.77  ? 155 ASN   C ND2 1 
ATOM   2795 N N   . GLN   B 2 174 ? 130.842 139.294 83.603  1.00 53.35  ? 156 GLN   C N   1 
ATOM   2796 C CA  . GLN   B 2 174 ? 130.407 140.652 83.884  1.00 53.35  ? 156 GLN   C CA  1 
ATOM   2797 C C   . GLN   B 2 174 ? 130.014 140.725 85.347  1.00 53.35  ? 156 GLN   C C   1 
ATOM   2798 O O   . GLN   B 2 174 ? 129.499 139.757 85.909  1.00 53.35  ? 156 GLN   C O   1 
ATOM   2799 C CB  . GLN   B 2 174 ? 129.233 141.070 83.000  1.00 53.35  ? 156 GLN   C CB  1 
ATOM   2800 C CG  . GLN   B 2 174 ? 129.623 141.762 81.727  1.00 53.35  ? 156 GLN   C CG  1 
ATOM   2801 C CD  . GLN   B 2 174 ? 128.429 142.271 80.959  1.00 53.35  ? 156 GLN   C CD  1 
ATOM   2802 O OE1 . GLN   B 2 174 ? 127.386 141.626 80.917  1.00 53.35  ? 156 GLN   C OE1 1 
ATOM   2803 N NE2 . GLN   B 2 174 ? 128.576 143.431 80.338  1.00 53.35  ? 156 GLN   C NE2 1 
ATOM   2804 N N   . ILE   B 2 175 ? 130.250 141.878 85.954  1.00 47.62  ? 157 ILE   C N   1 
ATOM   2805 C CA  . ILE   B 2 175 ? 129.914 142.089 87.352  1.00 47.62  ? 157 ILE   C CA  1 
ATOM   2806 C C   . ILE   B 2 175 ? 129.610 143.564 87.553  1.00 47.62  ? 157 ILE   C C   1 
ATOM   2807 O O   . ILE   B 2 175 ? 130.282 144.433 86.992  1.00 47.62  ? 157 ILE   C O   1 
ATOM   2808 C CB  . ILE   B 2 175 ? 131.040 141.583 88.280  1.00 47.62  ? 157 ILE   C CB  1 
ATOM   2809 C CG1 . ILE   B 2 175 ? 130.578 141.567 89.731  1.00 47.62  ? 157 ILE   C CG1 1 
ATOM   2810 C CG2 . ILE   B 2 175 ? 132.289 142.409 88.131  1.00 47.62  ? 157 ILE   C CG2 1 
ATOM   2811 C CD1 . ILE   B 2 175 ? 131.479 140.800 90.634  1.00 47.62  ? 157 ILE   C CD1 1 
ATOM   2812 N N   . VAL   B 2 176 ? 128.570 143.845 88.325  1.00 44.31  ? 158 VAL   C N   1 
ATOM   2813 C CA  . VAL   B 2 176 ? 128.183 145.203 88.671  1.00 44.31  ? 158 VAL   C CA  1 
ATOM   2814 C C   . VAL   B 2 176 ? 128.525 145.424 90.130  1.00 44.31  ? 158 VAL   C C   1 
ATOM   2815 O O   . VAL   B 2 176 ? 128.097 144.659 90.999  1.00 44.31  ? 158 VAL   C O   1 
ATOM   2816 C CB  . VAL   B 2 176 ? 126.692 145.461 88.411  1.00 44.31  ? 158 VAL   C CB  1 
ATOM   2817 C CG1 . VAL   B 2 176 ? 126.337 146.860 88.816  1.00 44.31  ? 158 VAL   C CG1 1 
ATOM   2818 C CG2 . VAL   B 2 176 ? 126.363 145.238 86.958  1.00 44.31  ? 158 VAL   C CG2 1 
ATOM   2819 N N   . THR   B 2 177 ? 129.290 146.468 90.396  1.00 47.27  ? 159 THR   C N   1 
ATOM   2820 C CA  . THR   B 2 177 ? 129.788 146.767 91.723  1.00 47.27  ? 159 THR   C CA  1 
ATOM   2821 C C   . THR   B 2 177 ? 129.360 148.167 92.136  1.00 47.27  ? 159 THR   C C   1 
ATOM   2822 O O   . THR   B 2 177 ? 129.374 149.091 91.322  1.00 47.27  ? 159 THR   C O   1 
ATOM   2823 C CB  . THR   B 2 177 ? 131.306 146.649 91.752  1.00 47.27  ? 159 THR   C CB  1 
ATOM   2824 O OG1 . THR   B 2 177 ? 131.690 145.289 91.521  1.00 47.27  ? 159 THR   C OG1 1 
ATOM   2825 C CG2 . THR   B 2 177 ? 131.845 147.101 93.071  1.00 47.27  ? 159 THR   C CG2 1 
ATOM   2826 N N   . SER   B 2 178 ? 128.968 148.316 93.397  1.00 48.49  ? 160 SER   C N   1 
ATOM   2827 C CA  . SER   B 2 178 ? 128.623 149.600 93.984  1.00 48.49  ? 160 SER   C CA  1 
ATOM   2828 C C   . SER   B 2 178 ? 129.595 149.920 95.105  1.00 48.49  ? 160 SER   C C   1 
ATOM   2829 O O   . SER   B 2 178 ? 130.108 149.020 95.773  1.00 48.49  ? 160 SER   C O   1 
ATOM   2830 C CB  . SER   B 2 178 ? 127.204 149.600 94.523  1.00 48.49  ? 160 SER   C CB  1 
ATOM   2831 O OG  . SER   B 2 178 ? 127.138 148.900 95.750  1.00 48.49  ? 160 SER   C OG  1 
ATOM   2832 N N   . SER   B 2 179 ? 129.848 151.210 95.314  1.00 51.96  ? 161 SER   C N   1 
ATOM   2833 C CA  . SER   B 2 179 ? 130.858 151.645 96.266  1.00 51.96  ? 161 SER   C CA  1 
ATOM   2834 C C   . SER   B 2 179 ? 130.388 152.871 97.031  1.00 51.96  ? 161 SER   C C   1 
ATOM   2835 O O   . SER   B 2 179 ? 129.492 153.594 96.604  1.00 51.96  ? 161 SER   C O   1 
ATOM   2836 C CB  . SER   B 2 179 ? 132.180 151.963 95.570  1.00 51.96  ? 161 SER   C CB  1 
ATOM   2837 O OG  . SER   B 2 179 ? 132.000 152.950 94.576  1.00 51.96  ? 161 SER   C OG  1 
ATOM   2838 N N   . GLY   B 2 180 ? 131.045 153.124 98.155  1.00 53.27  ? 162 GLY   C N   1 
ATOM   2839 C CA  . GLY   B 2 180 ? 130.843 154.356 98.888  1.00 53.27  ? 162 GLY   C CA  1 
ATOM   2840 C C   . GLY   B 2 180 ? 131.554 155.532 98.248  1.00 53.27  ? 162 GLY   C C   1 
ATOM   2841 O O   . GLY   B 2 180 ? 132.000 156.452 98.937  1.00 53.27  ? 162 GLY   C O   1 
ATOM   2842 N N   . ASP   B 2 181 ? 131.679 155.493 96.922  1.00 54.19  ? 163 ASP   C N   1 
ATOM   2843 C CA  . ASP   B 2 181 ? 132.173 156.594 96.111  1.00 54.19  ? 163 ASP   C CA  1 
ATOM   2844 C C   . ASP   B 2 181 ? 131.054 157.332 95.398  1.00 54.19  ? 163 ASP   C C   1 
ATOM   2845 O O   . ASP   B 2 181 ? 131.333 158.151 94.517  1.00 54.19  ? 163 ASP   C O   1 
ATOM   2846 C CB  . ASP   B 2 181 ? 133.162 156.074 95.077  1.00 54.19  ? 163 ASP   C CB  1 
ATOM   2847 C CG  . ASP   B 2 181 ? 134.433 155.593 95.698  1.00 54.19  ? 163 ASP   C CG  1 
ATOM   2848 O OD1 . ASP   B 2 181 ? 134.806 156.124 96.764  1.00 54.19  ? 163 ASP   C OD1 1 
ATOM   2849 O OD2 . ASP   B 2 181 ? 135.056 154.674 95.127  1.00 54.19  ? 163 ASP   C OD2 1 
ATOM   2850 N N   . THR   B 2 182 ? 129.800 157.049 95.748  1.00 55.15  ? 164 THR   C N   1 
ATOM   2851 C CA  . THR   B 2 182 ? 128.634 157.520 95.007  1.00 55.15  ? 164 THR   C CA  1 
ATOM   2852 C C   . THR   B 2 182 ? 128.689 157.073 93.547  1.00 55.15  ? 164 THR   C C   1 
ATOM   2853 O O   . THR   B 2 182 ? 128.256 157.793 92.645  1.00 55.15  ? 164 THR   C O   1 
ATOM   2854 C CB  . THR   B 2 182 ? 128.489 159.042 95.099  1.00 55.15  ? 164 THR   C CB  1 
ATOM   2855 O OG1 . THR   B 2 182 ? 129.450 159.666 94.238  1.00 55.15  ? 164 THR   C OG1 1 
ATOM   2856 C CG2 . THR   B 2 182 ? 128.729 159.517 96.523  1.00 55.15  ? 164 THR   C CG2 1 
ATOM   2857 N N   . THR   B 2 183 ? 129.219 155.876 93.305  1.00 54.18  ? 165 THR   C N   1 
ATOM   2858 C CA  . THR   B 2 183 ? 129.484 155.429 91.946  1.00 54.18  ? 165 THR   C CA  1 
ATOM   2859 C C   . THR   B 2 183 ? 129.266 153.929 91.825  1.00 54.18  ? 165 THR   C C   1 
ATOM   2860 O O   . THR   B 2 183 ? 129.671 153.162 92.700  1.00 54.18  ? 165 THR   C O   1 
ATOM   2861 C CB  . THR   B 2 183 ? 130.914 155.777 91.520  1.00 54.18  ? 165 THR   C CB  1 
ATOM   2862 O OG1 . THR   B 2 183 ? 131.168 157.163 91.777  1.00 54.18  ? 165 THR   C OG1 1 
ATOM   2863 C CG2 . THR   B 2 183 ? 131.120 155.509 90.053  1.00 54.18  ? 165 THR   C CG2 1 
ATOM   2864 N N   . CYS   B 2 184 ? 128.624 153.525 90.735  1.00 52.50  ? 166 CYS   C N   1 
ATOM   2865 C CA  . CYS   B 2 184 ? 128.479 152.132 90.351  1.00 52.50  ? 166 CYS   C CA  1 
ATOM   2866 C C   . CYS   B 2 184 ? 129.276 151.873 89.080  1.00 52.50  ? 166 CYS   C C   1 
ATOM   2867 O O   . CYS   B 2 184 ? 129.438 152.764 88.243  1.00 52.50  ? 166 CYS   C O   1 
ATOM   2868 C CB  . CYS   B 2 184 ? 127.011 151.765 90.124  1.00 52.50  ? 166 CYS   C CB  1 
ATOM   2869 S SG  . CYS   B 2 184 ? 125.964 151.814 91.582  1.00 52.50  ? 166 CYS   C SG  1 
ATOM   2870 N N   . ALA   B 2 185 ? 129.768 150.650 88.932  1.00 48.76  ? 167 ALA   C N   1 
ATOM   2871 C CA  . ALA   B 2 185 ? 130.632 150.319 87.815  1.00 48.76  ? 167 ALA   C CA  1 
ATOM   2872 C C   . ALA   B 2 185 ? 130.301 148.938 87.281  1.00 48.76  ? 167 ALA   C C   1 
ATOM   2873 O O   . ALA   B 2 185 ? 129.750 148.092 87.985  1.00 48.76  ? 167 ALA   C O   1 
ATOM   2874 C CB  . ALA   B 2 185 ? 132.110 150.378 88.216  1.00 48.76  ? 167 ALA   C CB  1 
ATOM   2875 N N   . LEU   B 2 186 ? 130.662 148.720 86.023  1.00 48.29  ? 168 LEU   C N   1 
ATOM   2876 C CA  . LEU   B 2 186 ? 130.533 147.432 85.360  1.00 48.29  ? 168 LEU   C CA  1 
ATOM   2877 C C   . LEU   B 2 186 ? 131.907 146.978 84.902  1.00 48.29  ? 168 LEU   C C   1 
ATOM   2878 O O   . LEU   B 2 186 ? 132.643 147.752 84.284  1.00 48.29  ? 168 LEU   C O   1 
ATOM   2879 C CB  . LEU   B 2 186 ? 129.587 147.523 84.169  1.00 48.29  ? 168 LEU   C CB  1 
ATOM   2880 C CG  . LEU   B 2 186 ? 128.958 146.260 83.600  1.00 48.29  ? 168 LEU   C CG  1 
ATOM   2881 C CD1 . LEU   B 2 186 ? 127.855 146.680 82.701  1.00 48.29  ? 168 LEU   C CD1 1 
ATOM   2882 C CD2 . LEU   B 2 186 ? 129.946 145.414 82.819  1.00 48.29  ? 168 LEU   C CD2 1 
ATOM   2883 N N   . TRP   B 2 187 ? 132.241 145.729 85.181  1.00 50.49  ? 169 TRP   C N   1 
ATOM   2884 C CA  . TRP   B 2 187 ? 133.556 145.198 84.881  1.00 50.49  ? 169 TRP   C CA  1 
ATOM   2885 C C   . TRP   B 2 187 ? 133.470 144.042 83.899  1.00 50.49  ? 169 TRP   C C   1 
ATOM   2886 O O   . TRP   B 2 187 ? 132.429 143.403 83.740  1.00 50.49  ? 169 TRP   C O   1 
ATOM   2887 C CB  . TRP   B 2 187 ? 134.268 144.709 86.141  1.00 50.49  ? 169 TRP   C CB  1 
ATOM   2888 C CG  . TRP   B 2 187 ? 134.196 145.616 87.298  1.00 50.49  ? 169 TRP   C CG  1 
ATOM   2889 C CD1 . TRP   B 2 187 ? 133.154 145.769 88.151  1.00 50.49  ? 169 TRP   C CD1 1 
ATOM   2890 C CD2 . TRP   B 2 187 ? 135.224 146.486 87.759  1.00 50.49  ? 169 TRP   C CD2 1 
ATOM   2891 N NE1 . TRP   B 2 187 ? 133.462 146.692 89.112  1.00 50.49  ? 169 TRP   C NE1 1 
ATOM   2892 C CE2 . TRP   B 2 187 ? 134.731 147.149 88.890  1.00 50.49  ? 169 TRP   C CE2 1 
ATOM   2893 C CE3 . TRP   B 2 187 ? 136.509 146.781 87.316  1.00 50.49  ? 169 TRP   C CE3 1 
ATOM   2894 C CZ2 . TRP   B 2 187 ? 135.479 148.083 89.584  1.00 50.49  ? 169 TRP   C CZ2 1 
ATOM   2895 C CZ3 . TRP   B 2 187 ? 137.245 147.699 88.000  1.00 50.49  ? 169 TRP   C CZ3 1 
ATOM   2896 C CH2 . TRP   B 2 187 ? 136.735 148.343 89.123  1.00 50.49  ? 169 TRP   C CH2 1 
ATOM   2897 N N   . ASP   B 2 188 ? 134.589 143.785 83.239  1.00 55.75  ? 170 ASP   C N   1 
ATOM   2898 C CA  . ASP   B 2 188 ? 134.808 142.560 82.484  1.00 55.75  ? 170 ASP   C CA  1 
ATOM   2899 C C   . ASP   B 2 188 ? 135.837 141.754 83.257  1.00 55.75  ? 170 ASP   C C   1 
ATOM   2900 O O   . ASP   B 2 188 ? 136.999 142.157 83.357  1.00 55.75  ? 170 ASP   C O   1 
ATOM   2901 C CB  . ASP   B 2 188 ? 135.289 142.848 81.066  1.00 55.75  ? 170 ASP   C CB  1 
ATOM   2902 N N   . ILE   B 2 189 ? 135.408 140.622 83.812  1.00 58.70  ? 171 ILE   C N   1 
ATOM   2903 C CA  . ILE   B 2 189 ? 136.310 139.800 84.607  1.00 58.70  ? 171 ILE   C CA  1 
ATOM   2904 C C   . ILE   B 2 189 ? 137.461 139.291 83.753  1.00 58.70  ? 171 ILE   C C   1 
ATOM   2905 O O   . ILE   B 2 189 ? 138.601 139.189 84.220  1.00 58.70  ? 171 ILE   C O   1 
ATOM   2906 C CB  . ILE   B 2 189 ? 135.534 138.643 85.258  1.00 58.70  ? 171 ILE   C CB  1 
ATOM   2907 C CG1 . ILE   B 2 189 ? 134.407 139.182 86.123  1.00 58.70  ? 171 ILE   C CG1 1 
ATOM   2908 C CG2 . ILE   B 2 189 ? 136.461 137.771 86.087  1.00 58.70  ? 171 ILE   C CG2 1 
ATOM   2909 C CD1 . ILE   B 2 189 ? 133.373 138.160 86.435  1.00 58.70  ? 171 ILE   C CD1 1 
ATOM   2910 N N   . GLU   B 2 190 ? 137.185 138.959 82.491  1.00 62.11  ? 172 GLU   C N   1 
ATOM   2911 C CA  . GLU   B 2 190 ? 138.233 138.439 81.619  1.00 62.11  ? 172 GLU   C CA  1 
ATOM   2912 C C   . GLU   B 2 190 ? 139.317 139.480 81.366  1.00 62.11  ? 172 GLU   C C   1 
ATOM   2913 O O   . GLU   B 2 190 ? 140.509 139.154 81.359  1.00 62.11  ? 172 GLU   C O   1 
ATOM   2914 C CB  . GLU   B 2 190 ? 137.628 137.963 80.299  1.00 62.11  ? 172 GLU   C CB  1 
ATOM   2915 N N   . THR   B 2 191 ? 138.927 140.736 81.160  1.00 61.52  ? 173 THR   C N   1 
ATOM   2916 C CA  . THR   B 2 191 ? 139.886 141.788 80.841  1.00 61.52  ? 173 THR   C CA  1 
ATOM   2917 C C   . THR   B 2 191 ? 140.296 142.603 82.061  1.00 61.52  ? 173 THR   C C   1 
ATOM   2918 O O   . THR   B 2 191 ? 141.473 142.945 82.207  1.00 61.52  ? 173 THR   C O   1 
ATOM   2919 C CB  . THR   B 2 191 ? 139.310 142.720 79.774  1.00 61.52  ? 173 THR   C CB  1 
ATOM   2920 N N   . GLY   B 2 192 ? 139.354 142.923 82.941  1.00 62.41  ? 174 GLY   C N   1 
ATOM   2921 C CA  . GLY   B 2 192 ? 139.647 143.687 84.134  1.00 62.41  ? 174 GLY   C CA  1 
ATOM   2922 C C   . GLY   B 2 192 ? 139.341 145.164 84.057  1.00 62.41  ? 174 GLY   C C   1 
ATOM   2923 O O   . GLY   B 2 192 ? 139.772 145.910 84.940  1.00 62.41  ? 174 GLY   C O   1 
ATOM   2924 N N   . GLN   B 2 193 ? 138.615 145.608 83.041  1.00 59.48  ? 175 GLN   C N   1 
ATOM   2925 C CA  . GLN   B 2 193 ? 138.381 147.020 82.797  1.00 59.48  ? 175 GLN   C CA  1 
ATOM   2926 C C   . GLN   B 2 193 ? 136.967 147.404 83.200  1.00 59.48  ? 175 GLN   C C   1 
ATOM   2927 O O   . GLN   B 2 193 ? 136.088 146.554 83.354  1.00 59.48  ? 175 GLN   C O   1 
ATOM   2928 C CB  . GLN   B 2 193 ? 138.607 147.365 81.321  1.00 59.48  ? 175 GLN   C CB  1 
ATOM   2929 C CG  . GLN   B 2 193 ? 139.924 146.866 80.752  1.00 59.48  ? 175 GLN   C CG  1 
ATOM   2930 C CD  . GLN   B 2 193 ? 141.055 147.849 80.960  1.00 59.48  ? 175 GLN   C CD  1 
ATOM   2931 O OE1 . GLN   B 2 193 ? 140.840 149.059 81.003  1.00 59.48  ? 175 GLN   C OE1 1 
ATOM   2932 N NE2 . GLN   B 2 193 ? 142.270 147.332 81.088  1.00 59.48  ? 175 GLN   C NE2 1 
ATOM   2933 N N   . GLN   B 2 194 ? 136.758 148.705 83.367  1.00 55.67  ? 176 GLN   C N   1 
ATOM   2934 C CA  . GLN   B 2 194 ? 135.430 149.254 83.613  1.00 55.67  ? 176 GLN   C CA  1 
ATOM   2935 C C   . GLN   B 2 194 ? 134.791 149.562 82.269  1.00 55.67  ? 176 GLN   C C   1 
ATOM   2936 O O   . GLN   B 2 194 ? 135.148 150.541 81.609  1.00 55.67  ? 176 GLN   C O   1 
ATOM   2937 C CB  . GLN   B 2 194 ? 135.510 150.500 84.480  1.00 55.67  ? 176 GLN   C CB  1 
ATOM   2938 C CG  . GLN   B 2 194 ? 135.669 150.227 85.947  1.00 55.67  ? 176 GLN   C CG  1 
ATOM   2939 C CD  . GLN   B 2 194 ? 135.153 151.360 86.795  1.00 55.67  ? 176 GLN   C CD  1 
ATOM   2940 O OE1 . GLN   B 2 194 ? 134.393 152.200 86.324  1.00 55.67  ? 176 GLN   C OE1 1 
ATOM   2941 N NE2 . GLN   B 2 194 ? 135.563 151.392 88.054  1.00 55.67  ? 176 GLN   C NE2 1 
ATOM   2942 N N   . THR   B 2 195 ? 133.846 148.720 81.852  1.00 56.17  ? 177 THR   C N   1 
ATOM   2943 C CA  . THR   B 2 195 ? 133.138 148.985 80.608  1.00 56.17  ? 177 THR   C CA  1 
ATOM   2944 C C   . THR   B 2 195 ? 132.333 150.271 80.707  1.00 56.17  ? 177 THR   C C   1 
ATOM   2945 O O   . THR   B 2 195 ? 132.283 151.057 79.753  1.00 56.17  ? 177 THR   C O   1 
ATOM   2946 C CB  . THR   B 2 195 ? 132.236 147.808 80.249  1.00 56.17  ? 177 THR   C CB  1 
ATOM   2947 O OG1 . THR   B 2 195 ? 133.032 146.627 80.110  1.00 56.17  ? 177 THR   C OG1 1 
ATOM   2948 C CG2 . THR   B 2 195 ? 131.509 148.071 78.942  1.00 56.17  ? 177 THR   C CG2 1 
ATOM   2949 N N   . THR   B 2 196 ? 131.709 150.511 81.854  1.00 55.01  ? 178 THR   C N   1 
ATOM   2950 C CA  . THR   B 2 196 ? 130.980 151.748 82.072  1.00 55.01  ? 178 THR   C CA  1 
ATOM   2951 C C   . THR   B 2 196 ? 131.040 152.111 83.545  1.00 55.01  ? 178 THR   C C   1 
ATOM   2952 O O   . THR   B 2 196 ? 131.266 151.260 84.408  1.00 55.01  ? 178 THR   C O   1 
ATOM   2953 C CB  . THR   B 2 196 ? 129.527 151.639 81.609  1.00 55.01  ? 178 THR   C CB  1 
ATOM   2954 O OG1 . THR   B 2 196 ? 128.856 152.878 81.853  1.00 55.01  ? 178 THR   C OG1 1 
ATOM   2955 C CG2 . THR   B 2 196 ? 128.816 150.530 82.348  1.00 55.01  ? 178 THR   C CG2 1 
ATOM   2956 N N   . THR   B 2 197 ? 130.842 153.393 83.822  1.00 54.15  ? 179 THR   C N   1 
ATOM   2957 C CA  . THR   B 2 197 ? 130.740 153.900 85.180  1.00 54.15  ? 179 THR   C CA  1 
ATOM   2958 C C   . THR   B 2 197 ? 129.419 154.639 85.316  1.00 54.15  ? 179 THR   C C   1 
ATOM   2959 O O   . THR   B 2 197 ? 129.050 155.435 84.448  1.00 54.15  ? 179 THR   C O   1 
ATOM   2960 C CB  . THR   B 2 197 ? 131.933 154.795 85.537  1.00 54.15  ? 179 THR   C CB  1 
ATOM   2961 O OG1 . THR   B 2 197 ? 131.881 155.136 86.927  1.00 54.15  ? 179 THR   C OG1 1 
ATOM   2962 C CG2 . THR   B 2 197 ? 131.972 156.064 84.688  1.00 54.15  ? 179 THR   C CG2 1 
ATOM   2963 N N   . PHE   B 2 198 ? 128.690 154.335 86.381  1.00 52.42  ? 180 PHE   C N   1 
ATOM   2964 C CA  . PHE   B 2 198 ? 127.343 154.850 86.584  1.00 52.42  ? 180 PHE   C CA  1 
ATOM   2965 C C   . PHE   B 2 198 ? 127.422 156.003 87.575  1.00 52.42  ? 180 PHE   C C   1 
ATOM   2966 O O   . PHE   B 2 198 ? 127.245 155.828 88.779  1.00 52.42  ? 180 PHE   C O   1 
ATOM   2967 C CB  . PHE   B 2 198 ? 126.414 153.750 87.074  1.00 52.42  ? 180 PHE   C CB  1 
ATOM   2968 C CG  . PHE   B 2 198 ? 126.259 152.614 86.111  1.00 52.42  ? 180 PHE   C CG  1 
ATOM   2969 C CD1 . PHE   B 2 198 ? 125.337 152.675 85.093  1.00 52.42  ? 180 PHE   C CD1 1 
ATOM   2970 C CD2 . PHE   B 2 198 ? 127.023 151.480 86.234  1.00 52.42  ? 180 PHE   C CD2 1 
ATOM   2971 C CE1 . PHE   B 2 198 ? 125.193 151.637 84.223  1.00 52.42  ? 180 PHE   C CE1 1 
ATOM   2972 C CE2 . PHE   B 2 198 ? 126.876 150.443 85.360  1.00 52.42  ? 180 PHE   C CE2 1 
ATOM   2973 C CZ  . PHE   B 2 198 ? 125.962 150.520 84.360  1.00 52.42  ? 180 PHE   C CZ  1 
ATOM   2974 N N   . THR   B 2 199 ? 127.684 157.191 87.054  1.00 55.32  ? 181 THR   C N   1 
ATOM   2975 C CA  . THR   B 2 199 ? 127.721 158.400 87.854  1.00 55.32  ? 181 THR   C CA  1 
ATOM   2976 C C   . THR   B 2 199 ? 126.327 159.001 87.967  1.00 55.32  ? 181 THR   C C   1 
ATOM   2977 O O   . THR   B 2 199 ? 125.450 158.761 87.134  1.00 55.32  ? 181 THR   C O   1 
ATOM   2978 C CB  . THR   B 2 199 ? 128.675 159.419 87.236  1.00 55.32  ? 181 THR   C CB  1 
ATOM   2979 O OG1 . THR   B 2 199 ? 128.351 159.595 85.853  1.00 55.32  ? 181 THR   C OG1 1 
ATOM   2980 C CG2 . THR   B 2 199 ? 130.108 158.945 87.353  1.00 55.32  ? 181 THR   C CG2 1 
ATOM   2981 N N   . GLY   B 2 200 ? 126.129 159.796 89.013  1.00 54.97  ? 182 GLY   C N   1 
ATOM   2982 C CA  . GLY   B 2 200 ? 124.883 160.516 89.153  1.00 54.97  ? 182 GLY   C CA  1 
ATOM   2983 C C   . GLY   B 2 200 ? 124.378 160.616 90.572  1.00 54.97  ? 182 GLY   C C   1 
ATOM   2984 O O   . GLY   B 2 200 ? 123.554 161.479 90.882  1.00 54.97  ? 182 GLY   C O   1 
ATOM   2985 N N   . HIS   B 2 201 ? 124.860 159.744 91.445  1.00 52.75  ? 183 HIS   C N   1 
ATOM   2986 C CA  . HIS   B 2 201 ? 124.393 159.736 92.817  1.00 52.75  ? 183 HIS   C CA  1 
ATOM   2987 C C   . HIS   B 2 201 ? 125.037 160.870 93.604  1.00 52.75  ? 183 HIS   C C   1 
ATOM   2988 O O   . HIS   B 2 201 ? 126.002 161.502 93.168  1.00 52.75  ? 183 HIS   C O   1 
ATOM   2989 C CB  . HIS   B 2 201 ? 124.706 158.400 93.477  1.00 52.75  ? 183 HIS   C CB  1 
ATOM   2990 C CG  . HIS   B 2 201 ? 123.588 157.412 93.408  1.00 52.75  ? 183 HIS   C CG  1 
ATOM   2991 N ND1 . HIS   B 2 201 ? 122.413 157.568 94.107  1.00 52.75  ? 183 HIS   C ND1 1 
ATOM   2992 C CD2 . HIS   B 2 201 ? 123.475 156.242 92.739  1.00 52.75  ? 183 HIS   C CD2 1 
ATOM   2993 C CE1 . HIS   B 2 201 ? 121.620 156.543 93.863  1.00 52.75  ? 183 HIS   C CE1 1 
ATOM   2994 N NE2 . HIS   B 2 201 ? 122.242 155.724 93.037  1.00 52.75  ? 183 HIS   C NE2 1 
ATOM   2995 N N   . THR   B 2 202 ? 124.489 161.127 94.786  1.00 55.39  ? 184 THR   C N   1 
ATOM   2996 C CA  . THR   B 2 202 ? 125.034 162.131 95.681  1.00 55.39  ? 184 THR   C CA  1 
ATOM   2997 C C   . THR   B 2 202 ? 125.482 161.574 97.020  1.00 55.39  ? 184 THR   C C   1 
ATOM   2998 O O   . THR   B 2 202 ? 126.115 162.304 97.790  1.00 55.39  ? 184 THR   C O   1 
ATOM   2999 C CB  . THR   B 2 202 ? 124.011 163.248 95.926  1.00 55.39  ? 184 THR   C CB  1 
ATOM   3000 O OG1 . THR   B 2 202 ? 122.820 162.692 96.492  1.00 55.39  ? 184 THR   C OG1 1 
ATOM   3001 C CG2 . THR   B 2 202 ? 123.666 163.947 94.625  1.00 55.39  ? 184 THR   C CG2 1 
ATOM   3002 N N   . GLY   B 2 203 ? 125.176 160.317 97.325  1.00 55.83  ? 185 GLY   C N   1 
ATOM   3003 C CA  . GLY   B 2 203 ? 125.616 159.709 98.560  1.00 55.83  ? 185 GLY   C CA  1 
ATOM   3004 C C   . GLY   B 2 203 ? 126.130 158.308 98.306  1.00 55.83  ? 185 GLY   C C   1 
ATOM   3005 O O   . GLY   B 2 203 ? 126.052 157.790 97.192  1.00 55.83  ? 185 GLY   C O   1 
ATOM   3006 N N   . ASP   B 2 204 ? 126.661 157.704 99.362  1.00 55.20  ? 186 ASP   C N   1 
ATOM   3007 C CA  . ASP   B 2 204 ? 127.226 156.368 99.261  1.00 55.20  ? 186 ASP   C CA  1 
ATOM   3008 C C   . ASP   B 2 204 ? 126.174 155.353 98.844  1.00 55.20  ? 186 ASP   C C   1 
ATOM   3009 O O   . ASP   B 2 204 ? 125.257 155.060 99.615  1.00 55.20  ? 186 ASP   C O   1 
ATOM   3010 C CB  . ASP   B 2 204 ? 127.848 155.956 100.592 1.00 55.20  ? 186 ASP   C CB  1 
ATOM   3011 C CG  . ASP   B 2 204 ? 129.133 156.704 100.891 1.00 55.20  ? 186 ASP   C CG  1 
ATOM   3012 O OD1 . ASP   B 2 204 ? 129.390 157.734 100.234 1.00 55.20  ? 186 ASP   C OD1 1 
ATOM   3013 O OD2 . ASP   B 2 204 ? 129.887 156.260 101.782 1.00 55.20  ? 186 ASP   C OD2 1 
ATOM   3014 N N   . VAL   B 2 205 ? 126.292 154.806 97.633  1.00 51.70  ? 187 VAL   C N   1 
ATOM   3015 C CA  . VAL   B 2 205 ? 125.371 153.761 97.208  1.00 51.70  ? 187 VAL   C CA  1 
ATOM   3016 C C   . VAL   B 2 205 ? 125.642 152.502 98.014  1.00 51.70  ? 187 VAL   C C   1 
ATOM   3017 O O   . VAL   B 2 205 ? 126.781 152.026 98.101  1.00 51.70  ? 187 VAL   C O   1 
ATOM   3018 C CB  . VAL   B 2 205 ? 125.467 153.515 95.695  1.00 51.70  ? 187 VAL   C CB  1 
ATOM   3019 C CG1 . VAL   B 2 205 ? 126.864 153.219 95.273  1.00 51.70  ? 187 VAL   C CG1 1 
ATOM   3020 C CG2 . VAL   B 2 205 ? 124.581 152.360 95.304  1.00 51.70  ? 187 VAL   C CG2 1 
ATOM   3021 N N   . MET   B 2 206 ? 124.595 151.973 98.630  1.00 54.90  ? 188 MET   C N   1 
ATOM   3022 C CA  . MET   B 2 206 ? 124.711 150.874 99.566  1.00 54.90  ? 188 MET   C CA  1 
ATOM   3023 C C   . MET   B 2 206 ? 124.101 149.582 99.061  1.00 54.90  ? 188 MET   C C   1 
ATOM   3024 O O   . MET   B 2 206 ? 124.343 148.529 99.658  1.00 54.90  ? 188 MET   C O   1 
ATOM   3025 C CB  . MET   B 2 206 ? 124.043 151.240 100.895 1.00 54.90  ? 188 MET   C CB  1 
ATOM   3026 C CG  . MET   B 2 206 ? 124.790 152.242 101.728 1.00 54.90  ? 188 MET   C CG  1 
ATOM   3027 S SD  . MET   B 2 206 ? 124.111 152.320 103.395 1.00 54.90  ? 188 MET   C SD  1 
ATOM   3028 C CE  . MET   B 2 206 ? 123.572 150.628 103.633 1.00 54.90  ? 188 MET   C CE  1 
ATOM   3029 N N   . SER   B 2 207 ? 123.321 149.626 97.989  1.00 49.81  ? 189 SER   C N   1 
ATOM   3030 C CA  . SER   B 2 207 ? 122.601 148.453 97.536  1.00 49.81  ? 189 SER   C CA  1 
ATOM   3031 C C   . SER   B 2 207 ? 122.314 148.580 96.053  1.00 49.81  ? 189 SER   C C   1 
ATOM   3032 O O   . SER   B 2 207 ? 122.094 149.681 95.542  1.00 49.81  ? 189 SER   C O   1 
ATOM   3033 C CB  . SER   B 2 207 ? 121.302 148.281 98.317  1.00 49.81  ? 189 SER   C CB  1 
ATOM   3034 O OG  . SER   B 2 207 ? 120.411 149.343 98.042  1.00 49.81  ? 189 SER   C OG  1 
ATOM   3035 N N   . LEU   B 2 208 ? 122.320 147.447 95.365  1.00 45.49  ? 190 LEU   C N   1 
ATOM   3036 C CA  . LEU   B 2 208 ? 121.813 147.389 94.006  1.00 45.49  ? 190 LEU   C CA  1 
ATOM   3037 C C   . LEU   B 2 208 ? 121.071 146.080 93.809  1.00 45.49  ? 190 LEU   C C   1 
ATOM   3038 O O   . LEU   B 2 208 ? 121.465 145.048 94.353  1.00 45.49  ? 190 LEU   C O   1 
ATOM   3039 C CB  . LEU   B 2 208 ? 122.928 147.557 92.962  1.00 45.49  ? 190 LEU   C CB  1 
ATOM   3040 C CG  . LEU   B 2 208 ? 124.080 146.581 92.785  1.00 45.49  ? 190 LEU   C CG  1 
ATOM   3041 C CD1 . LEU   B 2 208 ? 123.758 145.587 91.723  1.00 45.49  ? 190 LEU   C CD1 1 
ATOM   3042 C CD2 . LEU   B 2 208 ? 125.308 147.351 92.400  1.00 45.49  ? 190 LEU   C CD2 1 
ATOM   3043 N N   . SER   B 2 209 ? 119.984 146.132 93.044  1.00 44.66  ? 191 SER   C N   1 
ATOM   3044 C CA  . SER   B 2 209 ? 119.164 144.960 92.778  1.00 44.66  ? 191 SER   C CA  1 
ATOM   3045 C C   . SER   B 2 209 ? 118.943 144.829 91.282  1.00 44.66  ? 191 SER   C C   1 
ATOM   3046 O O   . SER   B 2 209 ? 118.297 145.682 90.670  1.00 44.66  ? 191 SER   C O   1 
ATOM   3047 C CB  . SER   B 2 209 ? 117.829 145.034 93.518  1.00 44.66  ? 191 SER   C CB  1 
ATOM   3048 O OG  . SER   B 2 209 ? 117.027 146.090 93.034  1.00 44.66  ? 191 SER   C OG  1 
ATOM   3049 N N   . LEU   B 2 210 ? 119.475 143.756 90.707  1.00 48.24  ? 192 LEU   C N   1 
ATOM   3050 C CA  . LEU   B 2 210 ? 119.361 143.493 89.280  1.00 48.24  ? 192 LEU   C CA  1 
ATOM   3051 C C   . LEU   B 2 210 ? 117.933 143.158 88.880  1.00 48.24  ? 192 LEU   C C   1 
ATOM   3052 O O   . LEU   B 2 210 ? 117.213 142.462 89.599  1.00 48.24  ? 192 LEU   C O   1 
ATOM   3053 C CB  . LEU   B 2 210 ? 120.271 142.335 88.894  1.00 48.24  ? 192 LEU   C CB  1 
ATOM   3054 C CG  . LEU   B 2 210 ? 121.623 142.621 88.270  1.00 48.24  ? 192 LEU   C CG  1 
ATOM   3055 C CD1 . LEU   B 2 210 ? 122.374 143.634 89.081  1.00 48.24  ? 192 LEU   C CD1 1 
ATOM   3056 C CD2 . LEU   B 2 210 ? 122.386 141.326 88.227  1.00 48.24  ? 192 LEU   C CD2 1 
ATOM   3057 N N   . ALA   B 2 211 ? 117.530 143.647 87.715  1.00 52.39  ? 193 ALA   C N   1 
ATOM   3058 C CA  . ALA   B 2 211 ? 116.238 143.289 87.166  1.00 52.39  ? 193 ALA   C CA  1 
ATOM   3059 C C   . ALA   B 2 211 ? 116.257 141.836 86.701  1.00 52.39  ? 193 ALA   C C   1 
ATOM   3060 O O   . ALA   B 2 211 ? 117.321 141.291 86.394  1.00 52.39  ? 193 ALA   C O   1 
ATOM   3061 C CB  . ALA   B 2 211 ? 115.880 144.206 86.004  1.00 52.39  ? 193 ALA   C CB  1 
ATOM   3062 N N   . PRO   B 2 212 ? 115.097 141.178 86.659  1.00 57.97  ? 194 PRO   C N   1 
ATOM   3063 C CA  . PRO   B 2 212 ? 115.071 139.774 86.223  1.00 57.97  ? 194 PRO   C CA  1 
ATOM   3064 C C   . PRO   B 2 212 ? 115.636 139.548 84.833  1.00 57.97  ? 194 PRO   C C   1 
ATOM   3065 O O   . PRO   B 2 212 ? 116.264 138.510 84.596  1.00 57.97  ? 194 PRO   C O   1 
ATOM   3066 C CB  . PRO   B 2 212 ? 113.580 139.424 86.288  1.00 57.97  ? 194 PRO   C CB  1 
ATOM   3067 C CG  . PRO   B 2 212 ? 113.046 140.315 87.347  1.00 57.97  ? 194 PRO   C CG  1 
ATOM   3068 C CD  . PRO   B 2 212 ? 113.796 141.607 87.200  1.00 57.97  ? 194 PRO   C CD  1 
ATOM   3069 N N   . ASP   B 2 213 ? 115.439 140.485 83.904  1.00 60.82  ? 195 ASP   C N   1 
ATOM   3070 C CA  . ASP   B 2 213 ? 115.955 140.330 82.549  1.00 60.82  ? 195 ASP   C CA  1 
ATOM   3071 C C   . ASP   B 2 213 ? 117.428 140.698 82.422  1.00 60.82  ? 195 ASP   C C   1 
ATOM   3072 O O   . ASP   B 2 213 ? 118.003 140.503 81.347  1.00 60.82  ? 195 ASP   C O   1 
ATOM   3073 C CB  . ASP   B 2 213 ? 115.128 141.168 81.570  1.00 60.82  ? 195 ASP   C CB  1 
ATOM   3074 C CG  . ASP   B 2 213 ? 114.967 142.606 82.021  1.00 60.82  ? 195 ASP   C CG  1 
ATOM   3075 O OD1 . ASP   B 2 213 ? 115.499 142.958 83.094  1.00 60.82  ? 195 ASP   C OD1 1 
ATOM   3076 O OD2 . ASP   B 2 213 ? 114.308 143.386 81.302  1.00 60.82  ? 195 ASP   C OD2 1 
ATOM   3077 N N   . THR   B 2 214 ? 118.040 141.230 83.482  1.00 59.22  ? 196 THR   C N   1 
ATOM   3078 C CA  . THR   B 2 214 ? 119.476 141.514 83.526  1.00 59.22  ? 196 THR   C CA  1 
ATOM   3079 C C   . THR   B 2 214 ? 119.864 142.525 82.443  1.00 59.22  ? 196 THR   C C   1 
ATOM   3080 O O   . THR   B 2 214 ? 120.931 142.453 81.834  1.00 59.22  ? 196 THR   C O   1 
ATOM   3081 C CB  . THR   B 2 214 ? 120.287 140.215 83.418  1.00 59.22  ? 196 THR   C CB  1 
ATOM   3082 O OG1 . THR   B 2 214 ? 119.790 139.279 84.382  1.00 59.22  ? 196 THR   C OG1 1 
ATOM   3083 C CG2 . THR   B 2 214 ? 121.756 140.445 83.753  1.00 59.22  ? 196 THR   C CG2 1 
ATOM   3084 N N   . ARG   B 2 215 ? 118.971 143.478 82.187  1.00 55.19  ? 197 ARG   C N   1 
ATOM   3085 C CA  . ARG   B 2 215 ? 119.280 144.637 81.365  1.00 55.19  ? 197 ARG   C CA  1 
ATOM   3086 C C   . ARG   B 2 215 ? 119.091 145.952 82.101  1.00 55.19  ? 197 ARG   C C   1 
ATOM   3087 O O   . ARG   B 2 215 ? 119.554 146.986 81.609  1.00 55.19  ? 197 ARG   C O   1 
ATOM   3088 C CB  . ARG   B 2 215 ? 118.420 144.648 80.092  1.00 55.19  ? 197 ARG   C CB  1 
ATOM   3089 N N   . LEU   B 2 216 ? 118.428 145.941 83.254  1.00 48.53  ? 198 LEU   C N   1 
ATOM   3090 C CA  . LEU   B 2 216 ? 118.250 147.112 84.088  1.00 48.53  ? 198 LEU   C CA  1 
ATOM   3091 C C   . LEU   B 2 216 ? 118.713 146.765 85.493  1.00 48.53  ? 198 LEU   C C   1 
ATOM   3092 O O   . LEU   B 2 216 ? 118.793 145.593 85.859  1.00 48.53  ? 198 LEU   C O   1 
ATOM   3093 C CB  . LEU   B 2 216 ? 116.789 147.557 84.121  1.00 48.53  ? 198 LEU   C CB  1 
ATOM   3094 C CG  . LEU   B 2 216 ? 116.167 148.060 82.826  1.00 48.53  ? 198 LEU   C CG  1 
ATOM   3095 C CD1 . LEU   B 2 216 ? 114.686 148.322 83.029  1.00 48.53  ? 198 LEU   C CD1 1 
ATOM   3096 C CD2 . LEU   B 2 216 ? 116.871 149.289 82.294  1.00 48.53  ? 198 LEU   C CD2 1 
ATOM   3097 N N   . PHE   B 2 217 ? 119.029 147.784 86.282  1.00 45.34  ? 199 PHE   C N   1 
ATOM   3098 C CA  . PHE   B 2 217 ? 119.235 147.568 87.705  1.00 45.34  ? 199 PHE   C CA  1 
ATOM   3099 C C   . PHE   B 2 217 ? 119.026 148.875 88.447  1.00 45.34  ? 199 PHE   C C   1 
ATOM   3100 O O   . PHE   B 2 217 ? 119.404 149.939 87.959  1.00 45.34  ? 199 PHE   C O   1 
ATOM   3101 C CB  . PHE   B 2 217 ? 120.620 146.970 87.999  1.00 45.34  ? 199 PHE   C CB  1 
ATOM   3102 C CG  . PHE   B 2 217 ? 121.730 147.962 88.005  1.00 45.34  ? 199 PHE   C CG  1 
ATOM   3103 C CD1 . PHE   B 2 217 ? 122.334 148.338 86.839  1.00 45.34  ? 199 PHE   C CD1 1 
ATOM   3104 C CD2 . PHE   B 2 217 ? 122.178 148.513 89.184  1.00 45.34  ? 199 PHE   C CD2 1 
ATOM   3105 C CE1 . PHE   B 2 217 ? 123.343 149.241 86.841  1.00 45.34  ? 199 PHE   C CE1 1 
ATOM   3106 C CE2 . PHE   B 2 217 ? 123.199 149.426 89.177  1.00 45.34  ? 199 PHE   C CE2 1 
ATOM   3107 C CZ  . PHE   B 2 217 ? 123.776 149.784 88.001  1.00 45.34  ? 199 PHE   C CZ  1 
ATOM   3108 N N   . VAL   B 2 218 ? 118.410 148.788 89.616  1.00 45.63  ? 200 VAL   C N   1 
ATOM   3109 C CA  . VAL   B 2 218 ? 118.193 149.941 90.479  1.00 45.63  ? 200 VAL   C CA  1 
ATOM   3110 C C   . VAL   B 2 218 ? 119.201 149.904 91.614  1.00 45.63  ? 200 VAL   C C   1 
ATOM   3111 O O   . VAL   B 2 218 ? 119.642 148.836 92.048  1.00 45.63  ? 200 VAL   C O   1 
ATOM   3112 C CB  . VAL   B 2 218 ? 116.755 149.989 91.024  1.00 45.63  ? 200 VAL   C CB  1 
ATOM   3113 C CG1 . VAL   B 2 218 ? 115.796 150.440 89.947  1.00 45.63  ? 200 VAL   C CG1 1 
ATOM   3114 C CG2 . VAL   B 2 218 ? 116.356 148.648 91.536  1.00 45.63  ? 200 VAL   C CG2 1 
ATOM   3115 N N   . SER   B 2 219 ? 119.575 151.085 92.097  1.00 45.76  ? 201 SER   C N   1 
ATOM   3116 C CA  . SER   B 2 219 ? 120.560 151.222 93.156  1.00 45.76  ? 201 SER   C CA  1 
ATOM   3117 C C   . SER   B 2 219 ? 120.115 152.304 94.120  1.00 45.76  ? 201 SER   C C   1 
ATOM   3118 O O   . SER   B 2 219 ? 119.682 153.378 93.698  1.00 45.76  ? 201 SER   C O   1 
ATOM   3119 C CB  . SER   B 2 219 ? 121.929 151.563 92.587  1.00 45.76  ? 201 SER   C CB  1 
ATOM   3120 O OG  . SER   B 2 219 ? 121.906 152.826 91.951  1.00 45.76  ? 201 SER   C OG  1 
ATOM   3121 N N   . GLY   B 2 220 ? 120.227 152.024 95.412  1.00 48.87  ? 202 GLY   C N   1 
ATOM   3122 C CA  . GLY   B 2 220 ? 119.771 152.927 96.450  1.00 48.87  ? 202 GLY   C CA  1 
ATOM   3123 C C   . GLY   B 2 220 ? 120.944 153.555 97.171  1.00 48.87  ? 202 GLY   C C   1 
ATOM   3124 O O   . GLY   B 2 220 ? 122.004 152.943 97.305  1.00 48.87  ? 202 GLY   C O   1 
ATOM   3125 N N   . ALA   B 2 221 ? 120.751 154.780 97.644  1.00 51.32  ? 203 ALA   C N   1 
ATOM   3126 C CA  . ALA   B 2 221 ? 121.826 155.556 98.235  1.00 51.32  ? 203 ALA   C CA  1 
ATOM   3127 C C   . ALA   B 2 221 ? 121.365 156.180 99.540  1.00 51.32  ? 203 ALA   C C   1 
ATOM   3128 O O   . ALA   B 2 221 ? 120.173 156.248 99.838  1.00 51.32  ? 203 ALA   C O   1 
ATOM   3129 C CB  . ALA   B 2 221 ? 122.320 156.640 97.275  1.00 51.32  ? 203 ALA   C CB  1 
ATOM   3130 N N   . CYS   B 2 222 ? 122.339 156.640 100.325 1.00 57.95  ? 204 CYS   C N   1 
ATOM   3131 C CA  . CYS   B 2 222 ? 122.073 157.265 101.613 1.00 57.95  ? 204 CYS   C CA  1 
ATOM   3132 C C   . CYS   B 2 222 ? 121.440 158.641 101.484 1.00 57.95  ? 204 CYS   C C   1 
ATOM   3133 O O   . CYS   B 2 222 ? 121.032 159.213 102.498 1.00 57.95  ? 204 CYS   C O   1 
ATOM   3134 C CB  . CYS   B 2 222 ? 123.362 157.372 102.420 1.00 57.95  ? 204 CYS   C CB  1 
ATOM   3135 S SG  . CYS   B 2 222 ? 124.073 155.786 102.900 1.00 57.95  ? 204 CYS   C SG  1 
ATOM   3136 N N   . ASP   B 2 223 ? 121.360 159.188 100.280 1.00 56.75  ? 205 ASP   C N   1 
ATOM   3137 C CA  . ASP   B 2 223 ? 120.691 160.455 100.042 1.00 56.75  ? 205 ASP   C CA  1 
ATOM   3138 C C   . ASP   B 2 223 ? 119.188 160.314 99.913  1.00 56.75  ? 205 ASP   C C   1 
ATOM   3139 O O   . ASP   B 2 223 ? 118.536 161.249 99.435  1.00 56.75  ? 205 ASP   C O   1 
ATOM   3140 C CB  . ASP   B 2 223 ? 121.266 161.119 98.789  1.00 56.75  ? 205 ASP   C CB  1 
ATOM   3141 C CG  . ASP   B 2 223 ? 121.037 160.302 97.532  1.00 56.75  ? 205 ASP   C CG  1 
ATOM   3142 O OD1 . ASP   B 2 223 ? 120.468 159.195 97.617  1.00 56.75  ? 205 ASP   C OD1 1 
ATOM   3143 O OD2 . ASP   B 2 223 ? 121.431 160.772 96.446  1.00 56.75  ? 205 ASP   C OD2 1 
ATOM   3144 N N   . ALA   B 2 224 ? 118.630 159.175 100.320 1.00 55.58  ? 206 ALA   C N   1 
ATOM   3145 C CA  . ALA   B 2 224 ? 117.202 158.898 100.203 1.00 55.58  ? 206 ALA   C CA  1 
ATOM   3146 C C   . ALA   B 2 224 ? 116.747 159.028 98.752  1.00 55.58  ? 206 ALA   C C   1 
ATOM   3147 O O   . ALA   B 2 224 ? 115.948 159.893 98.394  1.00 55.58  ? 206 ALA   C O   1 
ATOM   3148 C CB  . ALA   B 2 224 ? 116.384 159.808 101.127 1.00 55.58  ? 206 ALA   C CB  1 
ATOM   3149 N N   . SER   B 2 225 ? 117.291 158.153 97.914  1.00 52.07  ? 207 SER   C N   1 
ATOM   3150 C CA  . SER   B 2 225 ? 116.969 158.158 96.497  1.00 52.07  ? 207 SER   C CA  1 
ATOM   3151 C C   . SER   B 2 225 ? 117.418 156.847 95.880  1.00 52.07  ? 207 SER   C C   1 
ATOM   3152 O O   . SER   B 2 225 ? 118.392 156.237 96.325  1.00 52.07  ? 207 SER   C O   1 
ATOM   3153 C CB  . SER   B 2 225 ? 117.632 159.332 95.773  1.00 52.07  ? 207 SER   C CB  1 
ATOM   3154 O OG  . SER   B 2 225 ? 117.282 159.340 94.403  1.00 52.07  ? 207 SER   C OG  1 
ATOM   3155 N N   . ALA   B 2 226 ? 116.697 156.426 94.854  1.00 47.15  ? 208 ALA   C N   1 
ATOM   3156 C CA  . ALA   B 2 226 ? 117.040 155.256 94.069  1.00 47.15  ? 208 ALA   C CA  1 
ATOM   3157 C C   . ALA   B 2 226 ? 116.920 155.609 92.601  1.00 47.15  ? 208 ALA   C C   1 
ATOM   3158 O O   . ALA   B 2 226 ? 115.986 156.305 92.199  1.00 47.15  ? 208 ALA   C O   1 
ATOM   3159 C CB  . ALA   B 2 226 ? 116.135 154.081 94.391  1.00 47.15  ? 208 ALA   C CB  1 
ATOM   3160 N N   . LYS   B 2 227 ? 117.857 155.129 91.804  1.00 49.95  ? 209 LYS   C N   1 
ATOM   3161 C CA  . LYS   B 2 227 ? 117.887 155.422 90.385  1.00 49.95  ? 209 LYS   C CA  1 
ATOM   3162 C C   . LYS   B 2 227 ? 117.851 154.129 89.592  1.00 49.95  ? 209 LYS   C C   1 
ATOM   3163 O O   . LYS   B 2 227 ? 118.539 153.164 89.931  1.00 49.95  ? 209 LYS   C O   1 
ATOM   3164 C CB  . LYS   B 2 227 ? 119.130 156.222 90.015  1.00 49.95  ? 209 LYS   C CB  1 
ATOM   3165 C CG  . LYS   B 2 227 ? 119.188 157.586 90.646  1.00 49.95  ? 209 LYS   C CG  1 
ATOM   3166 C CD  . LYS   B 2 227 ? 120.198 158.464 89.956  1.00 49.95  ? 209 LYS   C CD  1 
ATOM   3167 C CE  . LYS   B 2 227 ? 120.285 159.812 90.636  1.00 49.95  ? 209 LYS   C CE  1 
ATOM   3168 N NZ  . LYS   B 2 227 ? 119.005 160.557 90.535  1.00 49.95  ? 209 LYS   C NZ  1 
ATOM   3169 N N   . LEU   B 2 228 ? 117.053 154.118 88.533  1.00 52.73  ? 210 LEU   C N   1 
ATOM   3170 C CA  . LEU   B 2 228 ? 116.980 152.982 87.629  1.00 52.73  ? 210 LEU   C CA  1 
ATOM   3171 C C   . LEU   B 2 228 ? 117.963 153.194 86.484  1.00 52.73  ? 210 LEU   C C   1 
ATOM   3172 O O   . LEU   B 2 228 ? 117.900 154.208 85.785  1.00 52.73  ? 210 LEU   C O   1 
ATOM   3173 C CB  . LEU   B 2 228 ? 115.552 152.799 87.120  1.00 52.73  ? 210 LEU   C CB  1 
ATOM   3174 C CG  . LEU   B 2 228 ? 115.280 151.891 85.929  1.00 52.73  ? 210 LEU   C CG  1 
ATOM   3175 C CD1 . LEU   B 2 228 ? 115.280 150.444 86.327  1.00 52.73  ? 210 LEU   C CD1 1 
ATOM   3176 C CD2 . LEU   B 2 228 ? 113.960 152.251 85.294  1.00 52.73  ? 210 LEU   C CD2 1 
ATOM   3177 N N   . TRP   B 2 229 ? 118.870 152.244 86.303  1.00 50.37  ? 211 TRP   C N   1 
ATOM   3178 C CA  . TRP   B 2 229 ? 119.950 152.331 85.339  1.00 50.37  ? 211 TRP   C CA  1 
ATOM   3179 C C   . TRP   B 2 229 ? 119.709 151.379 84.180  1.00 50.37  ? 211 TRP   C C   1 
ATOM   3180 O O   . TRP   B 2 229 ? 119.014 150.370 84.312  1.00 50.37  ? 211 TRP   C O   1 
ATOM   3181 C CB  . TRP   B 2 229 ? 121.290 151.997 85.991  1.00 50.37  ? 211 TRP   C CB  1 
ATOM   3182 C CG  . TRP   B 2 229 ? 121.594 152.794 87.200  1.00 50.37  ? 211 TRP   C CG  1 
ATOM   3183 C CD1 . TRP   B 2 229 ? 121.369 152.441 88.489  1.00 50.37  ? 211 TRP   C CD1 1 
ATOM   3184 C CD2 . TRP   B 2 229 ? 122.219 154.075 87.237  1.00 50.37  ? 211 TRP   C CD2 1 
ATOM   3185 N NE1 . TRP   B 2 229 ? 121.797 153.428 89.329  1.00 50.37  ? 211 TRP   C NE1 1 
ATOM   3186 C CE2 . TRP   B 2 229 ? 122.320 154.447 88.581  1.00 50.37  ? 211 TRP   C CE2 1 
ATOM   3187 C CE3 . TRP   B 2 229 ? 122.694 154.947 86.259  1.00 50.37  ? 211 TRP   C CE3 1 
ATOM   3188 C CZ2 . TRP   B 2 229 ? 122.877 155.649 88.973  1.00 50.37  ? 211 TRP   C CZ2 1 
ATOM   3189 C CZ3 . TRP   B 2 229 ? 123.233 156.130 86.646  1.00 50.37  ? 211 TRP   C CZ3 1 
ATOM   3190 C CH2 . TRP   B 2 229 ? 123.327 156.477 87.988  1.00 50.37  ? 211 TRP   C CH2 1 
ATOM   3191 N N   . ASP   B 2 230 ? 120.303 151.706 83.042  1.00 54.53  ? 212 ASP   C N   1 
ATOM   3192 C CA  . ASP   B 2 230 ? 120.252 150.862 81.856  1.00 54.53  ? 212 ASP   C CA  1 
ATOM   3193 C C   . ASP   B 2 230 ? 121.664 150.367 81.592  1.00 54.53  ? 212 ASP   C C   1 
ATOM   3194 O O   . ASP   B 2 230 ? 122.546 151.151 81.231  1.00 54.53  ? 212 ASP   C O   1 
ATOM   3195 C CB  . ASP   B 2 230 ? 119.695 151.617 80.655  1.00 54.53  ? 212 ASP   C CB  1 
ATOM   3196 C CG  . ASP   B 2 230 ? 119.499 150.720 79.448  1.00 54.53  ? 212 ASP   C CG  1 
ATOM   3197 O OD1 . ASP   B 2 230 ? 118.541 149.918 79.451  1.00 54.53  ? 212 ASP   C OD1 1 
ATOM   3198 O OD2 . ASP   B 2 230 ? 120.307 150.804 78.502  1.00 54.53  ? 212 ASP   C OD2 1 
ATOM   3199 N N   . VAL   B 2 231 ? 121.866 149.064 81.762  1.00 53.71  ? 213 VAL   C N   1 
ATOM   3200 C CA  . VAL   B 2 231 ? 123.212 148.504 81.831  1.00 53.71  ? 213 VAL   C CA  1 
ATOM   3201 C C   . VAL   B 2 231 ? 123.974 148.749 80.536  1.00 53.71  ? 213 VAL   C C   1 
ATOM   3202 O O   . VAL   B 2 231 ? 125.145 149.145 80.549  1.00 53.71  ? 213 VAL   C O   1 
ATOM   3203 C CB  . VAL   B 2 231 ? 123.142 147.007 82.170  1.00 53.71  ? 213 VAL   C CB  1 
ATOM   3204 C CG1 . VAL   B 2 231 ? 124.504 146.407 82.134  1.00 53.71  ? 213 VAL   C CG1 1 
ATOM   3205 C CG2 . VAL   B 2 231 ? 122.529 146.811 83.538  1.00 53.71  ? 213 VAL   C CG2 1 
ATOM   3206 N N   . ARG   B 2 232 ? 123.324 148.523 79.397  1.00 54.87  ? 214 ARG   C N   1 
ATOM   3207 C CA  . ARG   B 2 232 ? 124.020 148.632 78.121  1.00 54.87  ? 214 ARG   C CA  1 
ATOM   3208 C C   . ARG   B 2 232 ? 124.302 150.085 77.765  1.00 54.87  ? 214 ARG   C C   1 
ATOM   3209 O O   . ARG   B 2 232 ? 125.457 150.469 77.552  1.00 54.87  ? 214 ARG   C O   1 
ATOM   3210 C CB  . ARG   B 2 232 ? 123.200 147.959 77.023  1.00 54.87  ? 214 ARG   C CB  1 
ATOM   3211 N N   . GLU   B 2 233 ? 123.255 150.908 77.687  1.00 57.59  ? 215 GLU   C N   1 
ATOM   3212 C CA  . GLU   B 2 233 ? 123.432 152.292 77.265  1.00 57.59  ? 215 GLU   C CA  1 
ATOM   3213 C C   . GLU   B 2 233 ? 124.243 153.084 78.282  1.00 57.59  ? 215 GLU   C C   1 
ATOM   3214 O O   . GLU   B 2 233 ? 125.220 153.753 77.926  1.00 57.59  ? 215 GLU   C O   1 
ATOM   3215 C CB  . GLU   B 2 233 ? 122.072 152.945 77.032  1.00 57.59  ? 215 GLU   C CB  1 
ATOM   3216 N N   . GLY   B 2 234 ? 123.860 153.019 79.549  1.00 60.79  ? 216 GLY   C N   1 
ATOM   3217 C CA  . GLY   B 2 234 ? 124.592 153.671 80.607  1.00 60.79  ? 216 GLY   C CA  1 
ATOM   3218 C C   . GLY   B 2 234 ? 124.050 155.006 81.062  1.00 60.79  ? 216 GLY   C C   1 
ATOM   3219 O O   . GLY   B 2 234 ? 124.841 155.925 81.295  1.00 60.79  ? 216 GLY   C O   1 
ATOM   3220 N N   . MET   B 2 235 ? 122.738 155.147 81.197  1.00 62.34  ? 217 MET   C N   1 
ATOM   3221 C CA  . MET   B 2 235 ? 122.132 156.395 81.629  1.00 62.34  ? 217 MET   C CA  1 
ATOM   3222 C C   . MET   B 2 235 ? 121.054 156.121 82.663  1.00 62.34  ? 217 MET   C C   1 
ATOM   3223 O O   . MET   B 2 235 ? 120.372 155.093 82.614  1.00 62.34  ? 217 MET   C O   1 
ATOM   3224 C CB  . MET   B 2 235 ? 121.526 157.157 80.446  1.00 62.34  ? 217 MET   C CB  1 
ATOM   3225 N N   . CYS   B 2 236 ? 120.899 157.050 83.600  1.00 68.54  ? 218 CYS   C N   1 
ATOM   3226 C CA  . CYS   B 2 236 ? 119.803 156.964 84.552  1.00 68.54  ? 218 CYS   C CA  1 
ATOM   3227 C C   . CYS   B 2 236 ? 118.493 157.289 83.856  1.00 68.54  ? 218 CYS   C C   1 
ATOM   3228 O O   . CYS   B 2 236 ? 118.387 158.290 83.143  1.00 68.54  ? 218 CYS   C O   1 
ATOM   3229 C CB  . CYS   B 2 236 ? 120.027 157.917 85.719  1.00 68.54  ? 218 CYS   C CB  1 
ATOM   3230 S SG  . CYS   B 2 236 ? 118.588 158.134 86.774  1.00 68.54  ? 218 CYS   C SG  1 
ATOM   3231 N N   . ARG   B 2 237 ? 117.496 156.437 84.055  1.00 69.03  ? 219 ARG   C N   1 
ATOM   3232 C CA  . ARG   B 2 237 ? 116.201 156.607 83.418  1.00 69.03  ? 219 ARG   C CA  1 
ATOM   3233 C C   . ARG   B 2 237 ? 115.167 157.243 84.331  1.00 69.03  ? 219 ARG   C C   1 
ATOM   3234 O O   . ARG   B 2 237 ? 114.408 158.105 83.885  1.00 69.03  ? 219 ARG   C O   1 
ATOM   3235 C CB  . ARG   B 2 237 ? 115.676 155.259 82.925  1.00 69.03  ? 219 ARG   C CB  1 
ATOM   3236 C CG  . ARG   B 2 237 ? 116.512 154.622 81.840  1.00 69.03  ? 219 ARG   C CG  1 
ATOM   3237 C CD  . ARG   B 2 237 ? 115.734 153.507 81.159  1.00 69.03  ? 219 ARG   C CD  1 
ATOM   3238 N NE  . ARG   B 2 237 ? 116.295 153.124 79.866  1.00 69.03  ? 219 ARG   C NE  1 
ATOM   3239 C CZ  . ARG   B 2 237 ? 116.306 153.901 78.788  1.00 69.03  ? 219 ARG   C CZ  1 
ATOM   3240 N NH1 . ARG   B 2 237 ? 115.780 155.117 78.829  1.00 69.03  ? 219 ARG   C NH1 1 
ATOM   3241 N NH2 . ARG   B 2 237 ? 116.842 153.457 77.660  1.00 69.03  ? 219 ARG   C NH2 1 
ATOM   3242 N N   . GLN   B 2 238 ? 115.104 156.829 85.592  1.00 65.08  ? 220 GLN   C N   1 
ATOM   3243 C CA  . GLN   B 2 238 ? 114.145 157.375 86.537  1.00 65.08  ? 220 GLN   C CA  1 
ATOM   3244 C C   . GLN   B 2 238 ? 114.806 157.520 87.897  1.00 65.08  ? 220 GLN   C C   1 
ATOM   3245 O O   . GLN   B 2 238 ? 115.724 156.775 88.240  1.00 65.08  ? 220 GLN   C O   1 
ATOM   3246 C CB  . GLN   B 2 238 ? 112.900 156.491 86.640  1.00 65.08  ? 220 GLN   C CB  1 
ATOM   3247 C CG  . GLN   B 2 238 ? 112.180 156.286 85.329  1.00 65.08  ? 220 GLN   C CG  1 
ATOM   3248 C CD  . GLN   B 2 238 ? 111.449 154.972 85.268  1.00 65.08  ? 220 GLN   C CD  1 
ATOM   3249 O OE1 . GLN   B 2 238 ? 111.384 154.241 86.253  1.00 65.08  ? 220 GLN   C OE1 1 
ATOM   3250 N NE2 . GLN   B 2 238 ? 110.888 154.661 84.107  1.00 65.08  ? 220 GLN   C NE2 1 
ATOM   3251 N N   . THR   B 2 239 ? 114.330 158.490 88.668  1.00 60.55  ? 221 THR   C N   1 
ATOM   3252 C CA  . THR   B 2 239 ? 114.898 158.826 89.968  1.00 60.55  ? 221 THR   C CA  1 
ATOM   3253 C C   . THR   B 2 239 ? 113.763 158.909 90.973  1.00 60.55  ? 221 THR   C C   1 
ATOM   3254 O O   . THR   B 2 239 ? 112.923 159.809 90.890  1.00 60.55  ? 221 THR   C O   1 
ATOM   3255 C CB  . THR   B 2 239 ? 115.664 160.145 89.912  1.00 60.55  ? 221 THR   C CB  1 
ATOM   3256 N N   . PHE   B 2 240 ? 113.744 157.986 91.925  1.00 55.11  ? 222 PHE   C N   1 
ATOM   3257 C CA  . PHE   B 2 240 ? 112.640 157.849 92.861  1.00 55.11  ? 222 PHE   C CA  1 
ATOM   3258 C C   . PHE   B 2 240 ? 113.032 158.433 94.207  1.00 55.11  ? 222 PHE   C C   1 
ATOM   3259 O O   . PHE   B 2 240 ? 114.067 158.064 94.770  1.00 55.11  ? 222 PHE   C O   1 
ATOM   3260 C CB  . PHE   B 2 240 ? 112.246 156.385 93.020  1.00 55.11  ? 222 PHE   C CB  1 
ATOM   3261 C CG  . PHE   B 2 240 ? 111.940 155.693 91.728  1.00 55.11  ? 222 PHE   C CG  1 
ATOM   3262 C CD1 . PHE   B 2 240 ? 112.919 154.989 91.057  1.00 55.11  ? 222 PHE   C CD1 1 
ATOM   3263 C CD2 . PHE   B 2 240 ? 110.673 155.724 91.197  1.00 55.11  ? 222 PHE   C CD2 1 
ATOM   3264 C CE1 . PHE   B 2 240 ? 112.640 154.346 89.880  1.00 55.11  ? 222 PHE   C CE1 1 
ATOM   3265 C CE2 . PHE   B 2 240 ? 110.396 155.078 90.023  1.00 55.11  ? 222 PHE   C CE2 1 
ATOM   3266 C CZ  . PHE   B 2 240 ? 111.383 154.390 89.366  1.00 55.11  ? 222 PHE   C CZ  1 
ATOM   3267 N N   . THR   B 2 241 ? 112.207 159.341 94.720  1.00 56.62  ? 223 THR   C N   1 
ATOM   3268 C CA  . THR   B 2 241 ? 112.467 160.023 95.985  1.00 56.62  ? 223 THR   C CA  1 
ATOM   3269 C C   . THR   B 2 241 ? 111.186 160.032 96.808  1.00 56.62  ? 223 THR   C C   1 
ATOM   3270 O O   . THR   B 2 241 ? 110.300 160.856 96.568  1.00 56.62  ? 223 THR   C O   1 
ATOM   3271 C CB  . THR   B 2 241 ? 112.962 161.442 95.751  1.00 56.62  ? 223 THR   C CB  1 
ATOM   3272 O OG1 . THR   B 2 241 ? 111.975 162.168 95.009  1.00 56.62  ? 223 THR   C OG1 1 
ATOM   3273 C CG2 . THR   B 2 241 ? 114.275 161.443 94.983  1.00 56.62  ? 223 THR   C CG2 1 
ATOM   3274 N N   . GLY   B 2 242 ? 111.079 159.118 97.767  1.00 56.50  ? 224 GLY   C N   1 
ATOM   3275 C CA  . GLY   B 2 242 ? 109.974 159.155 98.704  1.00 56.50  ? 224 GLY   C CA  1 
ATOM   3276 C C   . GLY   B 2 242 ? 110.377 158.922 100.145 1.00 56.50  ? 224 GLY   C C   1 
ATOM   3277 O O   . GLY   B 2 242 ? 109.597 159.169 101.067 1.00 56.50  ? 224 GLY   C O   1 
ATOM   3278 N N   . HIS   B 2 243 ? 111.602 158.456 100.349 1.00 56.20  ? 225 HIS   C N   1 
ATOM   3279 C CA  . HIS   B 2 243 ? 112.105 158.135 101.670 1.00 56.20  ? 225 HIS   C CA  1 
ATOM   3280 C C   . HIS   B 2 243 ? 112.640 159.378 102.373 1.00 56.20  ? 225 HIS   C C   1 
ATOM   3281 O O   . HIS   B 2 243 ? 112.765 160.457 101.791 1.00 56.20  ? 225 HIS   C O   1 
ATOM   3282 C CB  . HIS   B 2 243 ? 113.185 157.064 101.571 1.00 56.20  ? 225 HIS   C CB  1 
ATOM   3283 C CG  . HIS   B 2 243 ? 112.648 155.670 101.546 1.00 56.20  ? 225 HIS   C CG  1 
ATOM   3284 N ND1 . HIS   B 2 243 ? 113.378 154.601 101.082 1.00 56.20  ? 225 HIS   C ND1 1 
ATOM   3285 C CD2 . HIS   B 2 243 ? 111.474 155.161 101.984 1.00 56.20  ? 225 HIS   C CD2 1 
ATOM   3286 C CE1 . HIS   B 2 243 ? 112.661 153.498 101.196 1.00 56.20  ? 225 HIS   C CE1 1 
ATOM   3287 N NE2 . HIS   B 2 243 ? 111.504 153.811 101.746 1.00 56.20  ? 225 HIS   C NE2 1 
ATOM   3288 N N   . GLU   B 2 244 ? 112.953 159.209 103.657 1.00 59.31  ? 226 GLU   C N   1 
ATOM   3289 C CA  . GLU   B 2 244 ? 113.456 160.286 104.491 1.00 59.31  ? 226 GLU   C CA  1 
ATOM   3290 C C   . GLU   B 2 244 ? 114.842 160.023 105.049 1.00 59.31  ? 226 GLU   C C   1 
ATOM   3291 O O   . GLU   B 2 244 ? 115.432 160.933 105.639 1.00 59.31  ? 226 GLU   C O   1 
ATOM   3292 C CB  . GLU   B 2 244 ? 112.493 160.552 105.657 1.00 59.31  ? 226 GLU   C CB  1 
ATOM   3293 C CG  . GLU   B 2 244 ? 111.045 160.704 105.242 1.00 59.31  ? 226 GLU   C CG  1 
ATOM   3294 C CD  . GLU   B 2 244 ? 110.097 160.667 106.422 1.00 59.31  ? 226 GLU   C CD  1 
ATOM   3295 O OE1 . GLU   B 2 244 ? 109.698 161.750 106.900 1.00 59.31  ? 226 GLU   C OE1 1 
ATOM   3296 O OE2 . GLU   B 2 244 ? 109.749 159.555 106.873 1.00 59.31  ? 226 GLU   C OE2 1 
ATOM   3297 N N   . SER   B 2 245 ? 115.374 158.821 104.887 1.00 56.62  ? 227 SER   C N   1 
ATOM   3298 C CA  . SER   B 2 245 ? 116.705 158.485 105.355 1.00 56.62  ? 227 SER   C CA  1 
ATOM   3299 C C   . SER   B 2 245 ? 117.292 157.488 104.366 1.00 56.62  ? 227 SER   C C   1 
ATOM   3300 O O   . SER   B 2 245 ? 116.776 157.325 103.258 1.00 56.62  ? 227 SER   C O   1 
ATOM   3301 C CB  . SER   B 2 245 ? 116.652 157.962 106.798 1.00 56.62  ? 227 SER   C CB  1 
ATOM   3302 O OG  . SER   B 2 245 ? 117.802 157.194 107.104 1.00 56.62  ? 227 SER   C OG  1 
ATOM   3303 N N   . ASP   B 2 246 ? 118.366 156.818 104.762 1.00 57.75  ? 228 ASP   C N   1 
ATOM   3304 C CA  . ASP   B 2 246 ? 119.121 155.984 103.840 1.00 57.75  ? 228 ASP   C CA  1 
ATOM   3305 C C   . ASP   B 2 246 ? 118.287 154.804 103.359 1.00 57.75  ? 228 ASP   C C   1 
ATOM   3306 O O   . ASP   B 2 246 ? 117.297 154.417 103.977 1.00 57.75  ? 228 ASP   C O   1 
ATOM   3307 C CB  . ASP   B 2 246 ? 120.396 155.473 104.508 1.00 57.75  ? 228 ASP   C CB  1 
ATOM   3308 C CG  . ASP   B 2 246 ? 121.111 156.549 105.302 1.00 57.75  ? 228 ASP   C CG  1 
ATOM   3309 O OD1 . ASP   B 2 246 ? 121.128 157.713 104.851 1.00 57.75  ? 228 ASP   C OD1 1 
ATOM   3310 O OD2 . ASP   B 2 246 ? 121.659 156.231 106.378 1.00 57.75  ? 228 ASP   C OD2 1 
ATOM   3311 N N   . ILE   B 2 247 ? 118.706 154.226 102.238 1.00 50.52  ? 229 ILE   C N   1 
ATOM   3312 C CA  . ILE   B 2 247 ? 118.102 153.017 101.696 1.00 50.52  ? 229 ILE   C CA  1 
ATOM   3313 C C   . ILE   B 2 247 ? 119.107 151.891 101.872 1.00 50.52  ? 229 ILE   C C   1 
ATOM   3314 O O   . ILE   B 2 247 ? 120.125 151.846 101.173 1.00 50.52  ? 229 ILE   C O   1 
ATOM   3315 C CB  . ILE   B 2 247 ? 117.707 153.171 100.227 1.00 50.52  ? 229 ILE   C CB  1 
ATOM   3316 C CG1 . ILE   B 2 247 ? 116.561 154.156 100.088 1.00 50.52  ? 229 ILE   C CG1 1 
ATOM   3317 C CG2 . ILE   B 2 247 ? 117.301 151.836 99.651  1.00 50.52  ? 229 ILE   C CG2 1 
ATOM   3318 C CD1 . ILE   B 2 247 ? 115.931 154.135 98.746  1.00 50.52  ? 229 ILE   C CD1 1 
ATOM   3319 N N   . ASN   B 2 248 ? 118.827 150.982 102.800 1.00 51.78  ? 230 ASN   C N   1 
ATOM   3320 C CA  . ASN   B 2 248 ? 119.730 149.874 103.059 1.00 51.78  ? 230 ASN   C CA  1 
ATOM   3321 C C   . ASN   B 2 248 ? 119.509 148.710 102.108 1.00 51.78  ? 230 ASN   C C   1 
ATOM   3322 O O   . ASN   B 2 248 ? 120.471 148.060 101.693 1.00 51.78  ? 230 ASN   C O   1 
ATOM   3323 C CB  . ASN   B 2 248 ? 119.569 149.378 104.495 1.00 51.78  ? 230 ASN   C CB  1 
ATOM   3324 C CG  . ASN   B 2 248 ? 119.690 150.480 105.506 1.00 51.78  ? 230 ASN   C CG  1 
ATOM   3325 O OD1 . ASN   B 2 248 ? 120.576 151.327 105.417 1.00 51.78  ? 230 ASN   C OD1 1 
ATOM   3326 N ND2 . ASN   B 2 248 ? 118.800 150.480 106.483 1.00 51.78  ? 230 ASN   C ND2 1 
ATOM   3327 N N   . ALA   B 2 249 ? 118.260 148.427 101.766 1.00 47.61  ? 231 ALA   C N   1 
ATOM   3328 C CA  . ALA   B 2 249 ? 117.920 147.272 100.957 1.00 47.61  ? 231 ALA   C CA  1 
ATOM   3329 C C   . ALA   B 2 249 ? 117.034 147.687 99.797  1.00 47.61  ? 231 ALA   C C   1 
ATOM   3330 O O   . ALA   B 2 249 ? 116.253 148.633 99.898  1.00 47.61  ? 231 ALA   C O   1 
ATOM   3331 C CB  . ALA   B 2 249 ? 117.210 146.210 101.783 1.00 47.61  ? 231 ALA   C CB  1 
ATOM   3332 N N   . ILE   B 2 250 ? 117.152 146.948 98.701  1.00 44.12  ? 232 ILE   C N   1 
ATOM   3333 C CA  . ILE   B 2 250 ? 116.355 147.168 97.504  1.00 44.12  ? 232 ILE   C CA  1 
ATOM   3334 C C   . ILE   B 2 250 ? 116.232 145.837 96.776  1.00 44.12  ? 232 ILE   C C   1 
ATOM   3335 O O   . ILE   B 2 250 ? 117.182 145.051 96.741  1.00 44.12  ? 232 ILE   C O   1 
ATOM   3336 C CB  . ILE   B 2 250 ? 116.984 148.273 96.626  1.00 44.12  ? 232 ILE   C CB  1 
ATOM   3337 C CG1 . ILE   B 2 250 ? 116.038 148.691 95.512  1.00 44.12  ? 232 ILE   C CG1 1 
ATOM   3338 C CG2 . ILE   B 2 250 ? 118.300 147.831 96.041  1.00 44.12  ? 232 ILE   C CG2 1 
ATOM   3339 C CD1 . ILE   B 2 250 ? 116.447 149.951 94.846  1.00 44.12  ? 232 ILE   C CD1 1 
ATOM   3340 N N   . CYS   B 2 251 ? 115.053 145.563 96.222  1.00 46.35  ? 233 CYS   C N   1 
ATOM   3341 C CA  . CYS   B 2 251 ? 114.835 144.316 95.500  1.00 46.35  ? 233 CYS   C CA  1 
ATOM   3342 C C   . CYS   B 2 251 ? 113.719 144.482 94.483  1.00 46.35  ? 233 CYS   C C   1 
ATOM   3343 O O   . CYS   B 2 251 ? 112.705 145.119 94.762  1.00 46.35  ? 233 CYS   C O   1 
ATOM   3344 C CB  . CYS   B 2 251 ? 114.496 143.165 96.445  1.00 46.35  ? 233 CYS   C CB  1 
ATOM   3345 S SG  . CYS   B 2 251 ? 112.810 143.149 97.060  1.00 46.35  ? 233 CYS   C SG  1 
ATOM   3346 N N   . PHE   B 2 252 ? 113.919 143.904 93.307  1.00 47.31  ? 234 PHE   C N   1 
ATOM   3347 C CA  . PHE   B 2 252 ? 112.915 143.924 92.258  1.00 47.31  ? 234 PHE   C CA  1 
ATOM   3348 C C   . PHE   B 2 252 ? 111.748 142.989 92.552  1.00 47.31  ? 234 PHE   C C   1 
ATOM   3349 O O   . PHE   B 2 252 ? 111.902 141.927 93.156  1.00 47.31  ? 234 PHE   C O   1 
ATOM   3350 C CB  . PHE   B 2 252 ? 113.535 143.525 90.926  1.00 47.31  ? 234 PHE   C CB  1 
ATOM   3351 C CG  . PHE   B 2 252 ? 113.904 144.679 90.046  1.00 47.31  ? 234 PHE   C CG  1 
ATOM   3352 C CD1 . PHE   B 2 252 ? 112.971 145.228 89.201  1.00 47.31  ? 234 PHE   C CD1 1 
ATOM   3353 C CD2 . PHE   B 2 252 ? 115.175 145.182 90.029  1.00 47.31  ? 234 PHE   C CD2 1 
ATOM   3354 C CE1 . PHE   B 2 252 ? 113.296 146.264 88.377  1.00 47.31  ? 234 PHE   C CE1 1 
ATOM   3355 C CE2 . PHE   B 2 252 ? 115.497 146.216 89.205  1.00 47.31  ? 234 PHE   C CE2 1 
ATOM   3356 C CZ  . PHE   B 2 252 ? 114.552 146.757 88.380  1.00 47.31  ? 234 PHE   C CZ  1 
ATOM   3357 N N   . PHE   B 2 253 ? 110.567 143.409 92.111  1.00 55.33  ? 235 PHE   C N   1 
ATOM   3358 C CA  . PHE   B 2 253 ? 109.444 142.505 91.944  1.00 55.33  ? 235 PHE   C CA  1 
ATOM   3359 C C   . PHE   B 2 253 ? 109.813 141.437 90.914  1.00 55.33  ? 235 PHE   C C   1 
ATOM   3360 O O   . PHE   B 2 253 ? 110.579 141.708 89.984  1.00 55.33  ? 235 PHE   C O   1 
ATOM   3361 C CB  . PHE   B 2 253 ? 108.224 143.289 91.471  1.00 55.33  ? 235 PHE   C CB  1 
ATOM   3362 C CG  . PHE   B 2 253 ? 106.913 142.748 91.943  1.00 55.33  ? 235 PHE   C CG  1 
ATOM   3363 C CD1 . PHE   B 2 253 ? 106.438 143.048 93.195  1.00 55.33  ? 235 PHE   C CD1 1 
ATOM   3364 C CD2 . PHE   B 2 253 ? 106.126 141.987 91.104  1.00 55.33  ? 235 PHE   C CD2 1 
ATOM   3365 C CE1 . PHE   B 2 253 ? 105.221 142.562 93.615  1.00 55.33  ? 235 PHE   C CE1 1 
ATOM   3366 C CE2 . PHE   B 2 253 ? 104.915 141.504 91.520  1.00 55.33  ? 235 PHE   C CE2 1 
ATOM   3367 C CZ  . PHE   B 2 253 ? 104.462 141.791 92.774  1.00 55.33  ? 235 PHE   C CZ  1 
ATOM   3368 N N   . PRO   B 2 254 ? 109.303 140.211 91.060  1.00 55.40  ? 236 PRO   C N   1 
ATOM   3369 C CA  . PRO   B 2 254 ? 109.651 139.165 90.084  1.00 55.40  ? 236 PRO   C CA  1 
ATOM   3370 C C   . PRO   B 2 254 ? 109.239 139.508 88.666  1.00 55.40  ? 236 PRO   C C   1 
ATOM   3371 O O   . PRO   B 2 254 ? 109.890 139.068 87.712  1.00 55.40  ? 236 PRO   C O   1 
ATOM   3372 C CB  . PRO   B 2 254 ? 108.901 137.939 90.614  1.00 55.40  ? 236 PRO   C CB  1 
ATOM   3373 C CG  . PRO   B 2 254 ? 108.689 138.224 92.042  1.00 55.40  ? 236 PRO   C CG  1 
ATOM   3374 C CD  . PRO   B 2 254 ? 108.446 139.684 92.128  1.00 55.40  ? 236 PRO   C CD  1 
ATOM   3375 N N   . ASN   B 2 255 ? 108.168 140.286 88.508  1.00 59.89  ? 237 ASN   C N   1 
ATOM   3376 C CA  . ASN   B 2 255 ? 107.765 140.779 87.197  1.00 59.89  ? 237 ASN   C CA  1 
ATOM   3377 C C   . ASN   B 2 255 ? 108.855 141.620 86.550  1.00 59.89  ? 237 ASN   C C   1 
ATOM   3378 O O   . ASN   B 2 255 ? 108.953 141.670 85.319  1.00 59.89  ? 237 ASN   C O   1 
ATOM   3379 C CB  . ASN   B 2 255 ? 106.483 141.596 87.345  1.00 59.89  ? 237 ASN   C CB  1 
ATOM   3380 C CG  . ASN   B 2 255 ? 105.901 142.017 86.028  1.00 59.89  ? 237 ASN   C CG  1 
ATOM   3381 O OD1 . ASN   B 2 255 ? 106.195 141.432 84.987  1.00 59.89  ? 237 ASN   C OD1 1 
ATOM   3382 N ND2 . ASN   B 2 255 ? 105.057 143.038 86.063  1.00 59.89  ? 237 ASN   C ND2 1 
ATOM   3383 N N   . GLY   B 2 256 ? 109.685 142.276 87.353  1.00 58.18  ? 238 GLY   C N   1 
ATOM   3384 C CA  . GLY   B 2 256 ? 110.612 143.254 86.832  1.00 58.18  ? 238 GLY   C CA  1 
ATOM   3385 C C   . GLY   B 2 256 ? 110.021 144.625 86.612  1.00 58.18  ? 238 GLY   C C   1 
ATOM   3386 O O   . GLY   B 2 256 ? 110.649 145.449 85.941  1.00 58.18  ? 238 GLY   C O   1 
ATOM   3387 N N   . ASN   B 2 257 ? 108.834 144.898 87.152  1.00 60.30  ? 239 ASN   C N   1 
ATOM   3388 C CA  . ASN   B 2 257 ? 108.162 146.173 86.954  1.00 60.30  ? 239 ASN   C CA  1 
ATOM   3389 C C   . ASN   B 2 257 ? 107.912 146.920 88.254  1.00 60.30  ? 239 ASN   C C   1 
ATOM   3390 O O   . ASN   B 2 257 ? 107.210 147.934 88.246  1.00 60.30  ? 239 ASN   C O   1 
ATOM   3391 C CB  . ASN   B 2 257 ? 106.839 145.967 86.221  1.00 60.30  ? 239 ASN   C CB  1 
ATOM   3392 C CG  . ASN   B 2 257 ? 106.986 146.069 84.724  1.00 60.30  ? 239 ASN   C CG  1 
ATOM   3393 O OD1 . ASN   B 2 257 ? 107.547 147.032 84.209  1.00 60.30  ? 239 ASN   C OD1 1 
ATOM   3394 N ND2 . ASN   B 2 257 ? 106.477 145.073 84.012  1.00 60.30  ? 239 ASN   C ND2 1 
ATOM   3395 N N   . ALA   B 2 258 ? 108.455 146.448 89.367  1.00 54.42  ? 240 ALA   C N   1 
ATOM   3396 C CA  . ALA   B 2 258 ? 108.338 147.141 90.635  1.00 54.42  ? 240 ALA   C CA  1 
ATOM   3397 C C   . ALA   B 2 258 ? 109.521 146.746 91.497  1.00 54.42  ? 240 ALA   C C   1 
ATOM   3398 O O   . ALA   B 2 258 ? 110.203 145.757 91.227  1.00 54.42  ? 240 ALA   C O   1 
ATOM   3399 C CB  . ALA   B 2 258 ? 107.021 146.817 91.340  1.00 54.42  ? 240 ALA   C CB  1 
ATOM   3400 N N   . PHE   B 2 259 ? 109.774 147.536 92.531  1.00 48.15  ? 241 PHE   C N   1 
ATOM   3401 C CA  . PHE   B 2 259 ? 110.838 147.202 93.461  1.00 48.15  ? 241 PHE   C CA  1 
ATOM   3402 C C   . PHE   B 2 259 ? 110.536 147.796 94.824  1.00 48.15  ? 241 PHE   C C   1 
ATOM   3403 O O   . PHE   B 2 259 ? 109.997 148.899 94.927  1.00 48.15  ? 241 PHE   C O   1 
ATOM   3404 C CB  . PHE   B 2 259 ? 112.198 147.681 92.955  1.00 48.15  ? 241 PHE   C CB  1 
ATOM   3405 C CG  . PHE   B 2 259 ? 112.271 149.143 92.690  1.00 48.15  ? 241 PHE   C CG  1 
ATOM   3406 C CD1 . PHE   B 2 259 ? 111.903 149.654 91.472  1.00 48.15  ? 241 PHE   C CD1 1 
ATOM   3407 C CD2 . PHE   B 2 259 ? 112.739 150.006 93.650  1.00 48.15  ? 241 PHE   C CD2 1 
ATOM   3408 C CE1 . PHE   B 2 259 ? 111.983 150.990 91.232  1.00 48.15  ? 241 PHE   C CE1 1 
ATOM   3409 C CE2 . PHE   B 2 259 ? 112.819 151.338 93.409  1.00 48.15  ? 241 PHE   C CE2 1 
ATOM   3410 C CZ  . PHE   B 2 259 ? 112.443 151.829 92.203  1.00 48.15  ? 241 PHE   C CZ  1 
ATOM   3411 N N   . ALA   B 2 260 ? 110.880 147.052 95.861  1.00 44.88  ? 242 ALA   C N   1 
ATOM   3412 C CA  . ALA   B 2 260 ? 110.679 147.481 97.232  1.00 44.88  ? 242 ALA   C CA  1 
ATOM   3413 C C   . ALA   B 2 260 ? 111.975 148.043 97.782  1.00 44.88  ? 242 ALA   C C   1 
ATOM   3414 O O   . ALA   B 2 260 ? 113.058 147.535 97.487  1.00 44.88  ? 242 ALA   C O   1 
ATOM   3415 C CB  . ALA   B 2 260 ? 110.199 146.323 98.104  1.00 44.88  ? 242 ALA   C CB  1 
ATOM   3416 N N   . THR   B 2 261 ? 111.863 149.094 98.583  1.00 49.21  ? 243 THR   C N   1 
ATOM   3417 C CA  . THR   B 2 261 ? 113.015 149.834 99.073  1.00 49.21  ? 243 THR   C CA  1 
ATOM   3418 C C   . THR   B 2 261 ? 112.968 149.899 100.587 1.00 49.21  ? 243 THR   C C   1 
ATOM   3419 O O   . THR   B 2 261 ? 112.041 150.480 101.157 1.00 49.21  ? 243 THR   C O   1 
ATOM   3420 C CB  . THR   B 2 261 ? 113.048 151.244 98.487  1.00 49.21  ? 243 THR   C CB  1 
ATOM   3421 O OG1 . THR   B 2 261 ? 111.730 151.804 98.520  1.00 49.21  ? 243 THR   C OG1 1 
ATOM   3422 C CG2 . THR   B 2 261 ? 113.545 151.214 97.055  1.00 49.21  ? 243 THR   C CG2 1 
ATOM   3423 N N   . GLY   B 2 262 ? 113.972 149.319 101.234 1.00 50.53  ? 244 GLY   C N   1 
ATOM   3424 C CA  . GLY   B 2 262 ? 114.070 149.362 102.677 1.00 50.53  ? 244 GLY   C CA  1 
ATOM   3425 C C   . GLY   B 2 262 ? 114.888 150.560 103.123 1.00 50.53  ? 244 GLY   C C   1 
ATOM   3426 O O   . GLY   B 2 262 ? 115.890 150.905 102.508 1.00 50.53  ? 244 GLY   C O   1 
ATOM   3427 N N   . SER   B 2 263 ? 114.448 151.186 104.209 1.00 53.26  ? 245 SER   C N   1 
ATOM   3428 C CA  . SER   B 2 263 ? 115.065 152.412 104.676 1.00 53.26  ? 245 SER   C CA  1 
ATOM   3429 C C   . SER   B 2 263 ? 115.272 152.369 106.181 1.00 53.26  ? 245 SER   C C   1 
ATOM   3430 O O   . SER   B 2 263 ? 114.650 151.581 106.895 1.00 53.26  ? 245 SER   C O   1 
ATOM   3431 C CB  . SER   B 2 263 ? 114.222 153.632 104.302 1.00 53.26  ? 245 SER   C CB  1 
ATOM   3432 N N   . ASP   B 2 264 ? 116.150 153.251 106.656 1.00 59.01  ? 246 ASP   C N   1 
ATOM   3433 C CA  . ASP   B 2 264 ? 116.444 153.377 108.076 1.00 59.01  ? 246 ASP   C CA  1 
ATOM   3434 C C   . ASP   B 2 264 ? 115.308 153.992 108.883 1.00 59.01  ? 246 ASP   C C   1 
ATOM   3435 O O   . ASP   B 2 264 ? 115.387 153.992 110.115 1.00 59.01  ? 246 ASP   C O   1 
ATOM   3436 C CB  . ASP   B 2 264 ? 117.709 154.207 108.284 1.00 59.01  ? 246 ASP   C CB  1 
ATOM   3437 C CG  . ASP   B 2 264 ? 118.959 153.494 107.816 1.00 59.01  ? 246 ASP   C CG  1 
ATOM   3438 O OD1 . ASP   B 2 264 ? 118.979 152.247 107.856 1.00 59.01  ? 246 ASP   C OD1 1 
ATOM   3439 O OD2 . ASP   B 2 264 ? 119.923 154.178 107.416 1.00 59.01  ? 246 ASP   C OD2 1 
ATOM   3440 N N   . ASP   B 2 265 ? 114.269 154.516 108.240 1.00 59.63  ? 247 ASP   C N   1 
ATOM   3441 C CA  . ASP   B 2 265 ? 113.131 155.073 108.953 1.00 59.63  ? 247 ASP   C CA  1 
ATOM   3442 C C   . ASP   B 2 265 ? 111.996 154.069 109.133 1.00 59.63  ? 247 ASP   C C   1 
ATOM   3443 O O   . ASP   B 2 265 ? 110.852 154.479 109.362 1.00 59.63  ? 247 ASP   C O   1 
ATOM   3444 C CB  . ASP   B 2 265 ? 112.624 156.325 108.240 1.00 59.63  ? 247 ASP   C CB  1 
ATOM   3445 C CG  . ASP   B 2 265 ? 112.042 156.029 106.876 1.00 59.63  ? 247 ASP   C CG  1 
ATOM   3446 O OD1 . ASP   B 2 265 ? 111.383 156.924 106.307 1.00 59.63  ? 247 ASP   C OD1 1 
ATOM   3447 O OD2 . ASP   B 2 265 ? 112.244 154.910 106.363 1.00 59.63  ? 247 ASP   C OD2 1 
ATOM   3448 N N   . ALA   B 2 266 ? 112.287 152.775 109.013 1.00 58.04  ? 248 ALA   C N   1 
ATOM   3449 C CA  . ALA   B 2 266 ? 111.375 151.661 109.264 1.00 58.04  ? 248 ALA   C CA  1 
ATOM   3450 C C   . ALA   B 2 266 ? 110.246 151.542 108.252 1.00 58.04  ? 248 ALA   C C   1 
ATOM   3451 O O   . ALA   B 2 266 ? 109.300 150.788 108.491 1.00 58.04  ? 248 ALA   C O   1 
ATOM   3452 C CB  . ALA   B 2 266 ? 110.774 151.726 110.672 1.00 58.04  ? 248 ALA   C CB  1 
ATOM   3453 N N   . THR   B 2 267 ? 110.317 152.240 107.125 1.00 56.92  ? 249 THR   C N   1 
ATOM   3454 C CA  . THR   B 2 267 ? 109.265 152.214 106.120 1.00 56.92  ? 249 THR   C CA  1 
ATOM   3455 C C   . THR   B 2 267 ? 109.764 151.499 104.873 1.00 56.92  ? 249 THR   C C   1 
ATOM   3456 O O   . THR   B 2 267 ? 110.892 151.731 104.429 1.00 56.92  ? 249 THR   C O   1 
ATOM   3457 C CB  . THR   B 2 267 ? 108.807 153.632 105.773 1.00 56.92  ? 249 THR   C CB  1 
ATOM   3458 O OG1 . THR   B 2 267 ? 108.232 154.244 106.929 1.00 56.92  ? 249 THR   C OG1 1 
ATOM   3459 C CG2 . THR   B 2 267 ? 107.774 153.610 104.668 1.00 56.92  ? 249 THR   C CG2 1 
ATOM   3460 N N   . CYS   B 2 268 ? 108.928 150.627 104.320 1.00 55.07  ? 250 CYS   C N   1 
ATOM   3461 C CA  . CYS   B 2 268 ? 109.173 149.991 103.036 1.00 55.07  ? 250 CYS   C CA  1 
ATOM   3462 C C   . CYS   B 2 268 ? 108.144 150.480 102.031 1.00 55.07  ? 250 CYS   C C   1 
ATOM   3463 O O   . CYS   B 2 268 ? 106.951 150.542 102.332 1.00 55.07  ? 250 CYS   C O   1 
ATOM   3464 C CB  . CYS   B 2 268 ? 109.108 148.471 103.146 1.00 55.07  ? 250 CYS   C CB  1 
ATOM   3465 S SG  . CYS   B 2 268 ? 110.588 147.696 103.800 1.00 55.07  ? 250 CYS   C SG  1 
ATOM   3466 N N   . ARG   B 2 269 ? 108.607 150.828 100.841 1.00 54.69  ? 251 ARG   C N   1 
ATOM   3467 C CA  . ARG   B 2 269 ? 107.761 151.360 99.788  1.00 54.69  ? 251 ARG   C CA  1 
ATOM   3468 C C   . ARG   B 2 269 ? 107.882 150.480 98.560  1.00 54.69  ? 251 ARG   C C   1 
ATOM   3469 O O   . ARG   B 2 269 ? 108.958 149.955 98.270  1.00 54.69  ? 251 ARG   C O   1 
ATOM   3470 C CB  . ARG   B 2 269 ? 108.156 152.789 99.443  1.00 54.69  ? 251 ARG   C CB  1 
ATOM   3471 C CG  . ARG   B 2 269 ? 108.480 153.608 100.655 1.00 54.69  ? 251 ARG   C CG  1 
ATOM   3472 C CD  . ARG   B 2 269 ? 108.240 155.072 100.448 1.00 54.69  ? 251 ARG   C CD  1 
ATOM   3473 N NE  . ARG   B 2 269 ? 108.227 155.768 101.725 1.00 54.69  ? 251 ARG   C NE  1 
ATOM   3474 C CZ  . ARG   B 2 269 ? 107.205 156.483 102.178 1.00 54.69  ? 251 ARG   C CZ  1 
ATOM   3475 N NH1 . ARG   B 2 269 ? 106.108 156.610 101.452 1.00 54.69  ? 251 ARG   C NH1 1 
ATOM   3476 N NH2 . ARG   B 2 269 ? 107.286 157.082 103.358 1.00 54.69  ? 251 ARG   C NH2 1 
ATOM   3477 N N   . LEU   B 2 270 ? 106.785 150.325 97.839  1.00 53.14  ? 252 LEU   C N   1 
ATOM   3478 C CA  . LEU   B 2 270 ? 106.749 149.512 96.628  1.00 53.14  ? 252 LEU   C CA  1 
ATOM   3479 C C   . LEU   B 2 270 ? 106.625 150.447 95.436  1.00 53.14  ? 252 LEU   C C   1 
ATOM   3480 O O   . LEU   B 2 270 ? 105.521 150.833 95.048  1.00 53.14  ? 252 LEU   C O   1 
ATOM   3481 C CB  . LEU   B 2 270 ? 105.600 148.518 96.677  1.00 53.14  ? 252 LEU   C CB  1 
ATOM   3482 C CG  . LEU   B 2 270 ? 105.509 147.581 95.487  1.00 53.14  ? 252 LEU   C CG  1 
ATOM   3483 C CD1 . LEU   B 2 270 ? 106.576 146.517 95.583  1.00 53.14  ? 252 LEU   C CD1 1 
ATOM   3484 C CD2 . LEU   B 2 270 ? 104.141 146.960 95.421  1.00 53.14  ? 252 LEU   C CD2 1 
ATOM   3485 N N   . PHE   B 2 271 ? 107.758 150.805 94.854  1.00 53.89  ? 253 PHE   C N   1 
ATOM   3486 C CA  . PHE   B 2 271 ? 107.770 151.730 93.739  1.00 53.89  ? 253 PHE   C CA  1 
ATOM   3487 C C   . PHE   B 2 271 ? 107.360 151.027 92.456  1.00 53.89  ? 253 PHE   C C   1 
ATOM   3488 O O   . PHE   B 2 271 ? 107.443 149.806 92.334  1.00 53.89  ? 253 PHE   C O   1 
ATOM   3489 C CB  . PHE   B 2 271 ? 109.150 152.351 93.573  1.00 53.89  ? 253 PHE   C CB  1 
ATOM   3490 C CG  . PHE   B 2 271 ? 109.478 153.369 94.611  1.00 53.89  ? 253 PHE   C CG  1 
ATOM   3491 C CD1 . PHE   B 2 271 ? 108.825 154.577 94.640  1.00 53.89  ? 253 PHE   C CD1 1 
ATOM   3492 C CD2 . PHE   B 2 271 ? 110.433 153.112 95.564  1.00 53.89  ? 253 PHE   C CD2 1 
ATOM   3493 C CE1 . PHE   B 2 271 ? 109.120 155.505 95.592  1.00 53.89  ? 253 PHE   C CE1 1 
ATOM   3494 C CE2 . PHE   B 2 271 ? 110.732 154.033 96.515  1.00 53.89  ? 253 PHE   C CE2 1 
ATOM   3495 C CZ  . PHE   B 2 271 ? 110.077 155.233 96.533  1.00 53.89  ? 253 PHE   C CZ  1 
ATOM   3496 N N   . ASP   B 2 272 ? 106.915 151.812 91.493  1.00 65.76  ? 254 ASP   C N   1 
ATOM   3497 C CA  . ASP   B 2 272 ? 106.470 151.288 90.215  1.00 65.76  ? 254 ASP   C CA  1 
ATOM   3498 C C   . ASP   B 2 272 ? 107.131 152.061 89.088  1.00 65.76  ? 254 ASP   C C   1 
ATOM   3499 O O   . ASP   B 2 272 ? 107.363 153.267 89.202  1.00 65.76  ? 254 ASP   C O   1 
ATOM   3500 C CB  . ASP   B 2 272 ? 104.964 151.360 90.099  1.00 65.76  ? 254 ASP   C CB  1 
ATOM   3501 C CG  . ASP   B 2 272 ? 104.403 150.275 89.217  1.00 65.76  ? 254 ASP   C CG  1 
ATOM   3502 O OD1 . ASP   B 2 272 ? 105.155 149.734 88.382  1.00 65.76  ? 254 ASP   C OD1 1 
ATOM   3503 O OD2 . ASP   B 2 272 ? 103.218 149.937 89.385  1.00 65.76  ? 254 ASP   C OD2 1 
ATOM   3504 N N   . LEU   B 2 273 ? 107.429 151.360 88.001  1.00 65.50  ? 255 LEU   C N   1 
ATOM   3505 C CA  . LEU   B 2 273 ? 108.295 151.908 86.970  1.00 65.50  ? 255 LEU   C CA  1 
ATOM   3506 C C   . LEU   B 2 273 ? 107.514 152.612 85.868  1.00 65.50  ? 255 LEU   C C   1 
ATOM   3507 O O   . LEU   B 2 273 ? 107.872 153.724 85.470  1.00 65.50  ? 255 LEU   C O   1 
ATOM   3508 C CB  . LEU   B 2 273 ? 109.161 150.801 86.376  1.00 65.50  ? 255 LEU   C CB  1 
ATOM   3509 C CG  . LEU   B 2 273 ? 110.450 150.457 87.119  1.00 65.50  ? 255 LEU   C CG  1 
ATOM   3510 C CD1 . LEU   B 2 273 ? 110.164 149.715 88.400  1.00 65.50  ? 255 LEU   C CD1 1 
ATOM   3511 C CD2 . LEU   B 2 273 ? 111.363 149.633 86.233  1.00 65.50  ? 255 LEU   C CD2 1 
ATOM   3512 N N   . ARG   B 2 274 ? 106.451 151.986 85.360  1.00 75.44  ? 256 ARG   C N   1 
ATOM   3513 C CA  . ARG   B 2 274 ? 105.696 152.614 84.284  1.00 75.44  ? 256 ARG   C CA  1 
ATOM   3514 C C   . ARG   B 2 274 ? 104.890 153.819 84.742  1.00 75.44  ? 256 ARG   C C   1 
ATOM   3515 O O   . ARG   B 2 274 ? 104.414 154.578 83.893  1.00 75.44  ? 256 ARG   C O   1 
ATOM   3516 C CB  . ARG   B 2 274 ? 104.764 151.610 83.613  1.00 75.44  ? 256 ARG   C CB  1 
ATOM   3517 C CG  . ARG   B 2 274 ? 105.427 150.754 82.562  1.00 75.44  ? 256 ARG   C CG  1 
ATOM   3518 C CD  . ARG   B 2 274 ? 106.025 149.517 83.167  1.00 75.44  ? 256 ARG   C CD  1 
ATOM   3519 N NE  . ARG   B 2 274 ? 105.013 148.728 83.856  1.00 75.44  ? 256 ARG   C NE  1 
ATOM   3520 C CZ  . ARG   B 2 274 ? 104.196 147.873 83.251  1.00 75.44  ? 256 ARG   C CZ  1 
ATOM   3521 N NH1 . ARG   B 2 274 ? 103.302 147.194 83.957  1.00 75.44  ? 256 ARG   C NH1 1 
ATOM   3522 N NH2 . ARG   B 2 274 ? 104.273 147.697 81.940  1.00 75.44  ? 256 ARG   C NH2 1 
ATOM   3523 N N   . ALA   B 2 275 ? 104.720 154.016 86.044  1.00 75.31  ? 257 ALA   C N   1 
ATOM   3524 C CA  . ALA   B 2 275 ? 104.020 155.182 86.547  1.00 75.31  ? 257 ALA   C CA  1 
ATOM   3525 C C   . ALA   B 2 275 ? 104.924 156.158 87.283  1.00 75.31  ? 257 ALA   C C   1 
ATOM   3526 O O   . ALA   B 2 275 ? 104.486 157.277 87.567  1.00 75.31  ? 257 ALA   C O   1 
ATOM   3527 C CB  . ALA   B 2 275 ? 102.875 154.759 87.474  1.00 75.31  ? 257 ALA   C CB  1 
ATOM   3528 N N   . ASP   B 2 276 ? 106.159 155.772 87.590  1.00 75.41  ? 258 ASP   C N   1 
ATOM   3529 C CA  . ASP   B 2 276 ? 107.104 156.611 88.323  1.00 75.41  ? 258 ASP   C CA  1 
ATOM   3530 C C   . ASP   B 2 276 ? 106.480 157.145 89.610  1.00 75.41  ? 258 ASP   C C   1 
ATOM   3531 O O   . ASP   B 2 276 ? 106.406 158.350 89.848  1.00 75.41  ? 258 ASP   C O   1 
ATOM   3532 C CB  . ASP   B 2 276 ? 107.612 157.757 87.448  1.00 75.41  ? 258 ASP   C CB  1 
ATOM   3533 C CG  . ASP   B 2 276 ? 108.704 157.323 86.507  1.00 75.41  ? 258 ASP   C CG  1 
ATOM   3534 O OD1 . ASP   B 2 276 ? 109.439 156.383 86.861  1.00 75.41  ? 258 ASP   C OD1 1 
ATOM   3535 O OD2 . ASP   B 2 276 ? 108.834 157.923 85.423  1.00 75.41  ? 258 ASP   C OD2 1 
ATOM   3536 N N   . GLN   B 2 277 ? 106.030 156.219 90.447  1.00 71.28  ? 259 GLN   C N   1 
ATOM   3537 C CA  . GLN   B 2 277 ? 105.229 156.592 91.600  1.00 71.28  ? 259 GLN   C CA  1 
ATOM   3538 C C   . GLN   B 2 277 ? 105.313 155.485 92.636  1.00 71.28  ? 259 GLN   C C   1 
ATOM   3539 O O   . GLN   B 2 277 ? 105.614 154.335 92.319  1.00 71.28  ? 259 GLN   C O   1 
ATOM   3540 C CB  . GLN   B 2 277 ? 103.774 156.860 91.182  1.00 71.28  ? 259 GLN   C CB  1 
ATOM   3541 C CG  . GLN   B 2 277 ? 102.871 157.462 92.245  1.00 71.28  ? 259 GLN   C CG  1 
ATOM   3542 C CD  . GLN   B 2 277 ? 103.175 158.916 92.522  1.00 71.28  ? 259 GLN   C CD  1 
ATOM   3543 O OE1 . GLN   B 2 277 ? 103.929 159.555 91.790  1.00 71.28  ? 259 GLN   C OE1 1 
ATOM   3544 N NE2 . GLN   B 2 277 ? 102.587 159.451 93.586  1.00 71.28  ? 259 GLN   C NE2 1 
ATOM   3545 N N   . GLU   B 2 278 ? 105.044 155.852 93.882  1.00 64.99  ? 260 GLU   C N   1 
ATOM   3546 C CA  . GLU   B 2 278 ? 104.936 154.904 94.978  1.00 64.99  ? 260 GLU   C CA  1 
ATOM   3547 C C   . GLU   B 2 278 ? 103.525 154.339 95.023  1.00 64.99  ? 260 GLU   C C   1 
ATOM   3548 O O   . GLU   B 2 278 ? 102.551 155.084 94.886  1.00 64.99  ? 260 GLU   C O   1 
ATOM   3549 C CB  . GLU   B 2 278 ? 105.266 155.587 96.300  1.00 64.99  ? 260 GLU   C CB  1 
ATOM   3550 C CG  . GLU   B 2 278 ? 105.068 154.705 97.507  1.00 64.99  ? 260 GLU   C CG  1 
ATOM   3551 C CD  . GLU   B 2 278 ? 105.271 155.452 98.802  1.00 64.99  ? 260 GLU   C CD  1 
ATOM   3552 O OE1 . GLU   B 2 278 ? 105.599 156.656 98.746  1.00 64.99  ? 260 GLU   C OE1 1 
ATOM   3553 O OE2 . GLU   B 2 278 ? 105.092 154.843 99.877  1.00 64.99  ? 260 GLU   C OE2 1 
ATOM   3554 N N   . LEU   B 2 279 ? 103.414 153.026 95.214  1.00 64.44  ? 261 LEU   C N   1 
ATOM   3555 C CA  . LEU   B 2 279 ? 102.114 152.371 95.276  1.00 64.44  ? 261 LEU   C CA  1 
ATOM   3556 C C   . LEU   B 2 279 ? 101.673 152.102 96.710  1.00 64.44  ? 261 LEU   C C   1 
ATOM   3557 O O   . LEU   B 2 279 ? 100.615 152.573 97.131  1.00 64.44  ? 261 LEU   C O   1 
ATOM   3558 C CB  . LEU   B 2 279 ? 102.138 151.063 94.477  1.00 64.44  ? 261 LEU   C CB  1 
ATOM   3559 C CG  . LEU   B 2 279 ? 102.597 151.105 93.020  1.00 64.44  ? 261 LEU   C CG  1 
ATOM   3560 C CD1 . LEU   B 2 279 ? 102.278 149.783 92.364  1.00 64.44  ? 261 LEU   C CD1 1 
ATOM   3561 C CD2 . LEU   B 2 279 ? 101.948 152.240 92.269  1.00 64.44  ? 261 LEU   C CD2 1 
ATOM   3562 N N   . MET   B 2 280 ? 102.466 151.360 97.472  1.00 63.91  ? 262 MET   C N   1 
ATOM   3563 C CA  . MET   B 2 280 ? 102.080 150.930 98.805  1.00 63.91  ? 262 MET   C CA  1 
ATOM   3564 C C   . MET   B 2 280 ? 103.115 151.418 99.816  1.00 63.91  ? 262 MET   C C   1 
ATOM   3565 O O   . MET   B 2 280 ? 104.210 151.849 99.454  1.00 63.91  ? 262 MET   C O   1 
ATOM   3566 C CB  . MET   B 2 280 ? 101.921 149.405 98.844  1.00 63.91  ? 262 MET   C CB  1 
ATOM   3567 C CG  . MET   B 2 280 ? 101.392 148.839 100.144 1.00 63.91  ? 262 MET   C CG  1 
ATOM   3568 S SD  . MET   B 2 280 ? 99.716  149.426 100.464 1.00 63.91  ? 262 MET   C SD  1 
ATOM   3569 C CE  . MET   B 2 280 ? 98.790  148.495 99.246  1.00 63.91  ? 262 MET   C CE  1 
ATOM   3570 N N   . THR   B 2 281 ? 102.752 151.371 101.101 1.00 57.71  ? 263 THR   C N   1 
ATOM   3571 C CA  . THR   B 2 281 ? 103.593 151.887 102.183 1.00 57.71  ? 263 THR   C CA  1 
ATOM   3572 C C   . THR   B 2 281 ? 103.529 150.920 103.362 1.00 57.71  ? 263 THR   C C   1 
ATOM   3573 O O   . THR   B 2 281 ? 102.561 150.927 104.123 1.00 57.71  ? 263 THR   C O   1 
ATOM   3574 C CB  . THR   B 2 281 ? 103.149 153.279 102.602 1.00 57.71  ? 263 THR   C CB  1 
ATOM   3575 O OG1 . THR   B 2 281 ? 103.027 154.112 101.444 1.00 57.71  ? 263 THR   C OG1 1 
ATOM   3576 C CG2 . THR   B 2 281 ? 104.161 153.891 103.550 1.00 57.71  ? 263 THR   C CG2 1 
ATOM   3577 N N   . TYR   B 2 282 ? 104.569 150.106 103.521 1.00 55.20  ? 264 TYR   C N   1 
ATOM   3578 C CA  . TYR   B 2 282 ? 104.595 149.067 104.549 1.00 55.20  ? 264 TYR   C CA  1 
ATOM   3579 C C   . TYR   B 2 282 ? 105.264 149.617 105.804 1.00 55.20  ? 264 TYR   C C   1 
ATOM   3580 O O   . TYR   B 2 282 ? 106.441 149.383 106.075 1.00 55.20  ? 264 TYR   C O   1 
ATOM   3581 C CB  . TYR   B 2 282 ? 105.320 147.830 104.040 1.00 55.20  ? 264 TYR   C CB  1 
ATOM   3582 C CG  . TYR   B 2 282 ? 104.881 147.356 102.685 1.00 55.20  ? 264 TYR   C CG  1 
ATOM   3583 C CD1 . TYR   B 2 282 ? 105.601 147.678 101.559 1.00 55.20  ? 264 TYR   C CD1 1 
ATOM   3584 C CD2 . TYR   B 2 282 ? 103.763 146.568 102.535 1.00 55.20  ? 264 TYR   C CD2 1 
ATOM   3585 C CE1 . TYR   B 2 282 ? 105.210 147.249 100.328 1.00 55.20  ? 264 TYR   C CE1 1 
ATOM   3586 C CE2 . TYR   B 2 282 ? 103.372 146.131 101.300 1.00 55.20  ? 264 TYR   C CE2 1 
ATOM   3587 C CZ  . TYR   B 2 282 ? 104.098 146.479 100.203 1.00 55.20  ? 264 TYR   C CZ  1 
ATOM   3588 O OH  . TYR   B 2 282 ? 103.717 146.051 98.960  1.00 55.20  ? 264 TYR   C OH  1 
ATOM   3589 N N   . SER   B 2 283 ? 104.490 150.353 106.590 1.00 59.77  ? 265 SER   C N   1 
ATOM   3590 C CA  . SER   B 2 283 ? 104.978 150.919 107.837 1.00 59.77  ? 265 SER   C CA  1 
ATOM   3591 C C   . SER   B 2 283 ? 103.972 150.670 108.946 1.00 59.77  ? 265 SER   C C   1 
ATOM   3592 O O   . SER   B 2 283 ? 102.760 150.738 108.721 1.00 59.77  ? 265 SER   C O   1 
ATOM   3593 C CB  . SER   B 2 283 ? 105.238 152.424 107.700 1.00 59.77  ? 265 SER   C CB  1 
ATOM   3594 N N   . HIS   B 2 284 ? 104.478 150.395 110.142 1.00 66.89  ? 266 HIS   C N   1 
ATOM   3595 C CA  . HIS   B 2 284 ? 103.639 150.158 111.304 1.00 66.89  ? 266 HIS   C CA  1 
ATOM   3596 C C   . HIS   B 2 284 ? 103.968 151.146 112.413 1.00 66.89  ? 266 HIS   C C   1 
ATOM   3597 O O   . HIS   B 2 284 ? 105.068 151.703 112.477 1.00 66.89  ? 266 HIS   C O   1 
ATOM   3598 C CB  . HIS   B 2 284 ? 103.793 148.736 111.836 1.00 66.89  ? 266 HIS   C CB  1 
ATOM   3599 C CG  . HIS   B 2 284 ? 102.620 148.278 112.640 1.00 66.89  ? 266 HIS   C CG  1 
ATOM   3600 N ND1 . HIS   B 2 284 ? 102.556 148.417 114.008 1.00 66.89  ? 266 HIS   C ND1 1 
ATOM   3601 C CD2 . HIS   B 2 284 ? 101.453 147.706 112.265 1.00 66.89  ? 266 HIS   C CD2 1 
ATOM   3602 C CE1 . HIS   B 2 284 ? 101.405 147.937 114.444 1.00 66.89  ? 266 HIS   C CE1 1 
ATOM   3603 N NE2 . HIS   B 2 284 ? 100.716 147.501 113.406 1.00 66.89  ? 266 HIS   C NE2 1 
ATOM   3604 N N   . ASP   B 2 285 ? 102.986 151.359 113.292 1.00 67.22  ? 267 ASP   C N   1 
ATOM   3605 C CA  . ASP   B 2 285 ? 103.171 152.291 114.398 1.00 67.22  ? 267 ASP   C CA  1 
ATOM   3606 C C   . ASP   B 2 285 ? 104.242 151.806 115.368 1.00 67.22  ? 267 ASP   C C   1 
ATOM   3607 O O   . ASP   B 2 285 ? 105.104 152.585 115.785 1.00 67.22  ? 267 ASP   C O   1 
ATOM   3608 C CB  . ASP   B 2 285 ? 101.846 152.506 115.126 1.00 67.22  ? 267 ASP   C CB  1 
ATOM   3609 N N   . ASN   B 2 286 ? 104.216 150.523 115.729 1.00 68.40  ? 268 ASN   C N   1 
ATOM   3610 C CA  . ASN   B 2 286 ? 105.092 149.996 116.768 1.00 68.40  ? 268 ASN   C CA  1 
ATOM   3611 C C   . ASN   B 2 286 ? 106.414 149.471 116.225 1.00 68.40  ? 268 ASN   C C   1 
ATOM   3612 O O   . ASN   B 2 286 ? 107.025 148.591 116.845 1.00 68.40  ? 268 ASN   C O   1 
ATOM   3613 C CB  . ASN   B 2 286 ? 104.374 148.903 117.562 1.00 68.40  ? 268 ASN   C CB  1 
ATOM   3614 C CG  . ASN   B 2 286 ? 103.956 147.726 116.701 1.00 68.40  ? 268 ASN   C CG  1 
ATOM   3615 O OD1 . ASN   B 2 286 ? 104.243 147.677 115.505 1.00 68.40  ? 268 ASN   C OD1 1 
ATOM   3616 N ND2 . ASN   B 2 286 ? 103.269 146.766 117.310 1.00 68.40  ? 268 ASN   C ND2 1 
ATOM   3617 N N   . ILE   B 2 287 ? 106.875 149.980 115.088 1.00 65.61  ? 269 ILE   C N   1 
ATOM   3618 C CA  . ILE   B 2 287 ? 108.170 149.618 114.527 1.00 65.61  ? 269 ILE   C CA  1 
ATOM   3619 C C   . ILE   B 2 287 ? 108.971 150.892 114.311 1.00 65.61  ? 269 ILE   C C   1 
ATOM   3620 O O   . ILE   B 2 287 ? 108.485 151.834 113.675 1.00 65.61  ? 269 ILE   C O   1 
ATOM   3621 C CB  . ILE   B 2 287 ? 108.024 148.844 113.209 1.00 65.61  ? 269 ILE   C CB  1 
ATOM   3622 C CG1 . ILE   B 2 287 ? 107.360 147.494 113.451 1.00 65.61  ? 269 ILE   C CG1 1 
ATOM   3623 C CG2 . ILE   B 2 287 ? 109.377 148.671 112.562 1.00 65.61  ? 269 ILE   C CG2 1 
ATOM   3624 C CD1 . ILE   B 2 287 ? 107.345 146.604 112.236 1.00 65.61  ? 269 ILE   C CD1 1 
ATOM   3625 N N   . ILE   B 2 288 ? 110.190 150.924 114.844 1.00 64.69  ? 270 ILE   C N   1 
ATOM   3626 C CA  . ILE   B 2 288 ? 111.078 152.066 114.652 1.00 64.69  ? 270 ILE   C CA  1 
ATOM   3627 C C   . ILE   B 2 288 ? 112.447 151.680 114.120 1.00 64.69  ? 270 ILE   C C   1 
ATOM   3628 O O   . ILE   B 2 288 ? 113.130 152.530 113.521 1.00 64.69  ? 270 ILE   C O   1 
ATOM   3629 C CB  . ILE   B 2 288 ? 111.225 152.865 115.964 1.00 64.69  ? 270 ILE   C CB  1 
ATOM   3630 C CG1 . ILE   B 2 288 ? 111.808 151.979 117.064 1.00 64.69  ? 270 ILE   C CG1 1 
ATOM   3631 C CG2 . ILE   B 2 288 ? 109.890 153.452 116.389 1.00 64.69  ? 270 ILE   C CG2 1 
ATOM   3632 C CD1 . ILE   B 2 288 ? 111.874 152.649 118.420 1.00 64.69  ? 270 ILE   C CD1 1 
ATOM   3633 N N   . CYS   B 2 289 ? 112.900 150.445 114.304 1.00 61.99  ? 271 CYS   C N   1 
ATOM   3634 C CA  . CYS   B 2 289 ? 114.183 150.026 113.761 1.00 61.99  ? 271 CYS   C CA  1 
ATOM   3635 C C   . CYS   B 2 289 ? 114.139 150.024 112.241 1.00 61.99  ? 271 CYS   C C   1 
ATOM   3636 O O   . CYS   B 2 289 ? 113.144 149.619 111.633 1.00 61.99  ? 271 CYS   C O   1 
ATOM   3637 C CB  . CYS   B 2 289 ? 114.541 148.640 114.277 1.00 61.99  ? 271 CYS   C CB  1 
ATOM   3638 S SG  . CYS   B 2 289 ? 113.217 147.433 114.080 1.00 61.99  ? 271 CYS   C SG  1 
ATOM   3639 N N   . GLY   B 2 290 ? 115.222 150.480 111.625 1.00 54.89  ? 272 GLY   C N   1 
ATOM   3640 C CA  . GLY   B 2 290 ? 115.280 150.515 110.183 1.00 54.89  ? 272 GLY   C CA  1 
ATOM   3641 C C   . GLY   B 2 290 ? 115.409 149.135 109.577 1.00 54.89  ? 272 GLY   C C   1 
ATOM   3642 O O   . GLY   B 2 290 ? 115.756 148.158 110.239 1.00 54.89  ? 272 GLY   C O   1 
ATOM   3643 N N   . ILE   B 2 291 ? 115.122 149.059 108.279 1.00 48.96  ? 273 ILE   C N   1 
ATOM   3644 C CA  . ILE   B 2 291 ? 115.200 147.792 107.575 1.00 48.96  ? 273 ILE   C CA  1 
ATOM   3645 C C   . ILE   B 2 291 ? 116.659 147.447 107.339 1.00 48.96  ? 273 ILE   C C   1 
ATOM   3646 O O   . ILE   B 2 291 ? 117.523 148.327 107.245 1.00 48.96  ? 273 ILE   C O   1 
ATOM   3647 C CB  . ILE   B 2 291 ? 114.432 147.861 106.247 1.00 48.96  ? 273 ILE   C CB  1 
ATOM   3648 C CG1 . ILE   B 2 291 ? 113.053 148.454 106.455 1.00 48.96  ? 273 ILE   C CG1 1 
ATOM   3649 C CG2 . ILE   B 2 291 ? 114.269 146.493 105.662 1.00 48.96  ? 273 ILE   C CG2 1 
ATOM   3650 C CD1 . ILE   B 2 291 ? 112.186 147.633 107.288 1.00 48.96  ? 273 ILE   C CD1 1 
ATOM   3651 N N   . THR   B 2 292 ? 116.945 146.159 107.240 1.00 49.61  ? 274 THR   C N   1 
ATOM   3652 C CA  . THR   B 2 292 ? 118.270 145.691 106.877 1.00 49.61  ? 274 THR   C CA  1 
ATOM   3653 C C   . THR   B 2 292 ? 118.312 144.928 105.565 1.00 49.61  ? 274 THR   C C   1 
ATOM   3654 O O   . THR   B 2 292 ? 119.319 144.998 104.863 1.00 49.61  ? 274 THR   C O   1 
ATOM   3655 C CB  . THR   B 2 292 ? 118.840 144.795 107.975 1.00 49.61  ? 274 THR   C CB  1 
ATOM   3656 O OG1 . THR   B 2 292 ? 118.180 143.525 107.942 1.00 49.61  ? 274 THR   C OG1 1 
ATOM   3657 C CG2 . THR   B 2 292 ? 118.616 145.422 109.323 1.00 49.61  ? 274 THR   C CG2 1 
ATOM   3658 N N   . SER   B 2 293 ? 117.256 144.202 105.217 1.00 50.07  ? 275 SER   C N   1 
ATOM   3659 C CA  . SER   B 2 293 ? 117.196 143.468 103.966 1.00 50.07  ? 275 SER   C CA  1 
ATOM   3660 C C   . SER   B 2 293 ? 115.743 143.342 103.549 1.00 50.07  ? 275 SER   C C   1 
ATOM   3661 O O   . SER   B 2 293 ? 114.849 143.260 104.393 1.00 50.07  ? 275 SER   C O   1 
ATOM   3662 C CB  . SER   B 2 293 ? 117.835 142.084 104.091 1.00 50.07  ? 275 SER   C CB  1 
ATOM   3663 O OG  . SER   B 2 293 ? 119.220 142.184 104.371 1.00 50.07  ? 275 SER   C OG  1 
ATOM   3664 N N   . VAL   B 2 294 ? 115.513 143.328 102.243 1.00 47.02  ? 276 VAL   C N   1 
ATOM   3665 C CA  . VAL   B 2 294 ? 114.182 143.151 101.682 1.00 47.02  ? 276 VAL   C CA  1 
ATOM   3666 C C   . VAL   B 2 294 ? 114.267 142.139 100.555 1.00 47.02  ? 276 VAL   C C   1 
ATOM   3667 O O   . VAL   B 2 294 ? 115.133 142.249 99.681  1.00 47.02  ? 276 VAL   C O   1 
ATOM   3668 C CB  . VAL   B 2 294 ? 113.597 144.479 101.176 1.00 47.02  ? 276 VAL   C CB  1 
ATOM   3669 C CG1 . VAL   B 2 294 ? 112.378 144.239 100.354 1.00 47.02  ? 276 VAL   C CG1 1 
ATOM   3670 C CG2 . VAL   B 2 294 ? 113.264 145.377 102.339 1.00 47.02  ? 276 VAL   C CG2 1 
ATOM   3671 N N   . SER   B 2 295 ? 113.372 141.156 100.572 1.00 48.86  ? 277 SER   C N   1 
ATOM   3672 C CA  . SER   B 2 295 ? 113.256 140.192 99.491  1.00 48.86  ? 277 SER   C CA  1 
ATOM   3673 C C   . SER   B 2 295 ? 111.788 139.881 99.262  1.00 48.86  ? 277 SER   C C   1 
ATOM   3674 O O   . SER   B 2 295 ? 110.935 140.153 100.107 1.00 48.86  ? 277 SER   C O   1 
ATOM   3675 C CB  . SER   B 2 295 ? 114.036 138.911 99.788  1.00 48.86  ? 277 SER   C CB  1 
ATOM   3676 O OG  . SER   B 2 295 ? 113.886 137.976 98.736  1.00 48.86  ? 277 SER   C OG  1 
ATOM   3677 N N   . PHE   B 2 296 ? 111.500 139.313 98.105  1.00 51.25  ? 278 PHE   C N   1 
ATOM   3678 C CA  . PHE   B 2 296 ? 110.154 138.945 97.700  1.00 51.25  ? 278 PHE   C CA  1 
ATOM   3679 C C   . PHE   B 2 296 ? 110.019 137.426 97.680  1.00 51.25  ? 278 PHE   C C   1 
ATOM   3680 O O   . PHE   B 2 296 ? 110.931 136.689 98.055  1.00 51.25  ? 278 PHE   C O   1 
ATOM   3681 C CB  . PHE   B 2 296 ? 109.829 139.524 96.329  1.00 51.25  ? 278 PHE   C CB  1 
ATOM   3682 C CG  . PHE   B 2 296 ? 109.120 140.835 96.369  1.00 51.25  ? 278 PHE   C CG  1 
ATOM   3683 C CD1 . PHE   B 2 296 ? 107.838 140.925 96.836  1.00 51.25  ? 278 PHE   C CD1 1 
ATOM   3684 C CD2 . PHE   B 2 296 ? 109.731 141.976 95.902  1.00 51.25  ? 278 PHE   C CD2 1 
ATOM   3685 C CE1 . PHE   B 2 296 ? 107.183 142.131 96.855  1.00 51.25  ? 278 PHE   C CE1 1 
ATOM   3686 C CE2 . PHE   B 2 296 ? 109.081 143.178 95.920  1.00 51.25  ? 278 PHE   C CE2 1 
ATOM   3687 C CZ  . PHE   B 2 296 ? 107.807 143.255 96.396  1.00 51.25  ? 278 PHE   C CZ  1 
ATOM   3688 N N   . SER   B 2 297 ? 108.861 136.962 97.233  1.00 57.57  ? 279 SER   C N   1 
ATOM   3689 C CA  . SER   B 2 297 ? 108.616 135.554 96.976  1.00 57.57  ? 279 SER   C CA  1 
ATOM   3690 C C   . SER   B 2 297 ? 108.469 135.333 95.477  1.00 57.57  ? 279 SER   C C   1 
ATOM   3691 O O   . SER   B 2 297 ? 108.399 136.278 94.689  1.00 57.57  ? 279 SER   C O   1 
ATOM   3692 C CB  . SER   B 2 297 ? 107.368 135.072 97.717  1.00 57.57  ? 279 SER   C CB  1 
ATOM   3693 O OG  . SER   B 2 297 ? 107.250 133.664 97.644  1.00 57.57  ? 279 SER   C OG  1 
ATOM   3694 N N   . LYS   B 2 298 ? 108.433 134.059 95.086  1.00 62.40  ? 280 LYS   C N   1 
ATOM   3695 C CA  . LYS   B 2 298 ? 108.370 133.728 93.667  1.00 62.40  ? 280 LYS   C CA  1 
ATOM   3696 C C   . LYS   B 2 298 ? 107.094 134.256 93.037  1.00 62.40  ? 280 LYS   C C   1 
ATOM   3697 O O   . LYS   B 2 298 ? 107.112 134.777 91.917  1.00 62.40  ? 280 LYS   C O   1 
ATOM   3698 C CB  . LYS   B 2 298 ? 108.475 132.219 93.478  1.00 62.40  ? 280 LYS   C CB  1 
ATOM   3699 C CG  . LYS   B 2 298 ? 108.516 131.772 92.036  1.00 62.40  ? 280 LYS   C CG  1 
ATOM   3700 C CD  . LYS   B 2 298 ? 108.348 130.267 91.932  1.00 62.40  ? 280 LYS   C CD  1 
ATOM   3701 C CE  . LYS   B 2 298 ? 108.351 129.811 90.481  1.00 62.40  ? 280 LYS   C CE  1 
ATOM   3702 N NZ  . LYS   B 2 298 ? 109.463 130.428 89.708  1.00 62.40  ? 280 LYS   C NZ  1 
ATOM   3703 N N   . SER   B 2 299 ? 105.974 134.129 93.739  1.00 64.68  ? 281 SER   C N   1 
ATOM   3704 C CA  . SER   B 2 299 ? 104.710 134.647 93.250  1.00 64.68  ? 281 SER   C CA  1 
ATOM   3705 C C   . SER   B 2 299 ? 104.577 136.144 93.446  1.00 64.68  ? 281 SER   C C   1 
ATOM   3706 O O   . SER   B 2 299 ? 103.655 136.744 92.890  1.00 64.68  ? 281 SER   C O   1 
ATOM   3707 C CB  . SER   B 2 299 ? 103.556 133.938 93.951  1.00 64.68  ? 281 SER   C CB  1 
ATOM   3708 O OG  . SER   B 2 299 ? 103.828 133.797 95.333  1.00 64.68  ? 281 SER   C OG  1 
ATOM   3709 N N   . GLY   B 2 300 ? 105.468 136.753 94.216  1.00 59.32  ? 282 GLY   C N   1 
ATOM   3710 C CA  . GLY   B 2 300 ? 105.396 138.175 94.475  1.00 59.32  ? 282 GLY   C CA  1 
ATOM   3711 C C   . GLY   B 2 300 ? 104.218 138.593 95.319  1.00 59.32  ? 282 GLY   C C   1 
ATOM   3712 O O   . GLY   B 2 300 ? 103.610 139.635 95.052  1.00 59.32  ? 282 GLY   C O   1 
ATOM   3713 N N   . ARG   B 2 301 ? 103.875 137.806 96.328  1.00 60.90  ? 283 ARG   C N   1 
ATOM   3714 C CA  . ARG   B 2 301 ? 102.841 138.162 97.289  1.00 60.90  ? 283 ARG   C CA  1 
ATOM   3715 C C   . ARG   B 2 301 ? 103.398 138.521 98.651  1.00 60.90  ? 283 ARG   C C   1 
ATOM   3716 O O   . ARG   B 2 301 ? 102.897 139.444 99.292  1.00 60.90  ? 283 ARG   C O   1 
ATOM   3717 C CB  . ARG   B 2 301 ? 101.841 137.017 97.449  1.00 60.90  ? 283 ARG   C CB  1 
ATOM   3718 C CG  . ARG   B 2 301 ? 100.672 137.346 98.354  1.00 60.90  ? 283 ARG   C CG  1 
ATOM   3719 C CD  . ARG   B 2 301 ? 100.014 138.650 97.938  1.00 60.90  ? 283 ARG   C CD  1 
ATOM   3720 N NE  . ARG   B 2 301 ? 98.756  138.899 98.634  1.00 60.90  ? 283 ARG   C NE  1 
ATOM   3721 C CZ  . ARG   B 2 301 ? 97.643  138.205 98.444  1.00 60.90  ? 283 ARG   C CZ  1 
ATOM   3722 N NH1 . ARG   B 2 301 ? 97.617  137.211 97.571  1.00 60.90  ? 283 ARG   C NH1 1 
ATOM   3723 N NH2 . ARG   B 2 301 ? 96.550  138.509 99.125  1.00 60.90  ? 283 ARG   C NH2 1 
ATOM   3724 N N   . LEU   B 2 302 ? 104.423 137.822 99.105  1.00 54.98  ? 284 LEU   C N   1 
ATOM   3725 C CA  . LEU   B 2 302 ? 105.030 138.106 100.387 1.00 54.98  ? 284 LEU   C CA  1 
ATOM   3726 C C   . LEU   B 2 302 ? 106.206 139.054 100.223 1.00 54.98  ? 284 LEU   C C   1 
ATOM   3727 O O   . LEU   B 2 302 ? 106.907 139.036 99.212  1.00 54.98  ? 284 LEU   C O   1 
ATOM   3728 C CB  . LEU   B 2 302 ? 105.500 136.817 101.058 1.00 54.98  ? 284 LEU   C CB  1 
ATOM   3729 C CG  . LEU   B 2 302 ? 104.440 135.758 101.321 1.00 54.98  ? 284 LEU   C CG  1 
ATOM   3730 C CD1 . LEU   B 2 302 ? 104.998 134.709 102.242 1.00 54.98  ? 284 LEU   C CD1 1 
ATOM   3731 C CD2 . LEU   B 2 302 ? 103.214 136.393 101.923 1.00 54.98  ? 284 LEU   C CD2 1 
ATOM   3732 N N   . LEU   B 2 303 ? 106.409 139.892 101.230 1.00 49.95  ? 285 LEU   C N   1 
ATOM   3733 C CA  . LEU   B 2 303 ? 107.547 140.800 101.287 1.00 49.95  ? 285 LEU   C CA  1 
ATOM   3734 C C   . LEU   B 2 303 ? 108.240 140.572 102.620 1.00 49.95  ? 285 LEU   C C   1 
ATOM   3735 O O   . LEU   B 2 303 ? 107.761 141.031 103.658 1.00 49.95  ? 285 LEU   C O   1 
ATOM   3736 C CB  . LEU   B 2 303 ? 107.116 142.249 101.138 1.00 49.95  ? 285 LEU   C CB  1 
ATOM   3737 C CG  . LEU   B 2 303 ? 108.240 143.272 101.018 1.00 49.95  ? 285 LEU   C CG  1 
ATOM   3738 C CD1 . LEU   B 2 303 ? 109.145 142.893 99.881  1.00 49.95  ? 285 LEU   C CD1 1 
ATOM   3739 C CD2 . LEU   B 2 303 ? 107.668 144.643 100.784 1.00 49.95  ? 285 LEU   C CD2 1 
ATOM   3740 N N   . LEU   B 2 304 ? 109.360 139.868 102.596 1.00 50.45  ? 286 LEU   C N   1 
ATOM   3741 C CA  . LEU   B 2 304 ? 110.135 139.623 103.799 1.00 50.45  ? 286 LEU   C CA  1 
ATOM   3742 C C   . LEU   B 2 304 ? 111.065 140.800 104.040 1.00 50.45  ? 286 LEU   C C   1 
ATOM   3743 O O   . LEU   B 2 304 ? 111.881 141.140 103.179 1.00 50.45  ? 286 LEU   C O   1 
ATOM   3744 C CB  . LEU   B 2 304 ? 110.934 138.328 103.688 1.00 50.45  ? 286 LEU   C CB  1 
ATOM   3745 C CG  . LEU   B 2 304 ? 110.163 137.037 103.933 1.00 50.45  ? 286 LEU   C CG  1 
ATOM   3746 C CD1 . LEU   B 2 304 ? 109.291 136.661 102.751 1.00 50.45  ? 286 LEU   C CD1 1 
ATOM   3747 C CD2 . LEU   B 2 304 ? 111.109 135.925 104.287 1.00 50.45  ? 286 LEU   C CD2 1 
ATOM   3748 N N   . ALA   B 2 305 ? 110.948 141.415 105.209 1.00 49.56  ? 287 ALA   C N   1 
ATOM   3749 C CA  . ALA   B 2 305 ? 111.760 142.560 105.580 1.00 49.56  ? 287 ALA   C CA  1 
ATOM   3750 C C   . ALA   B 2 305 ? 112.531 142.247 106.848 1.00 49.56  ? 287 ALA   C C   1 
ATOM   3751 O O   . ALA   B 2 305 ? 111.940 141.841 107.853 1.00 49.56  ? 287 ALA   C O   1 
ATOM   3752 C CB  . ALA   B 2 305 ? 110.891 143.800 105.776 1.00 49.56  ? 287 ALA   C CB  1 
ATOM   3753 N N   . GLY   B 2 306 ? 113.846 142.442 106.805 1.00 50.72  ? 288 GLY   C N   1 
ATOM   3754 C CA  . GLY   B 2 306 ? 114.700 142.196 107.949 1.00 50.72  ? 288 GLY   C CA  1 
ATOM   3755 C C   . GLY   B 2 306 ? 114.968 143.485 108.702 1.00 50.72  ? 288 GLY   C C   1 
ATOM   3756 O O   . GLY   B 2 306 ? 115.361 144.492 108.110 1.00 50.72  ? 288 GLY   C O   1 
ATOM   3757 N N   . TYR   B 2 307 ? 114.755 143.439 110.010 1.00 51.79  ? 289 TYR   C N   1 
ATOM   3758 C CA  . TYR   B 2 307 ? 114.821 144.618 110.854 1.00 51.79  ? 289 TYR   C CA  1 
ATOM   3759 C C   . TYR   B 2 307 ? 115.997 144.520 111.819 1.00 51.79  ? 289 TYR   C C   1 
ATOM   3760 O O   . TYR   B 2 307 ? 116.754 143.549 111.826 1.00 51.79  ? 289 TYR   C O   1 
ATOM   3761 C CB  . TYR   B 2 307 ? 113.517 144.795 111.621 1.00 51.79  ? 289 TYR   C CB  1 
ATOM   3762 C CG  . TYR   B 2 307 ? 112.335 145.176 110.779 1.00 51.79  ? 289 TYR   C CG  1 
ATOM   3763 C CD1 . TYR   B 2 307 ? 111.760 146.420 110.881 1.00 51.79  ? 289 TYR   C CD1 1 
ATOM   3764 C CD2 . TYR   B 2 307 ? 111.773 144.275 109.908 1.00 51.79  ? 289 TYR   C CD2 1 
ATOM   3765 C CE1 . TYR   B 2 307 ? 110.670 146.757 110.120 1.00 51.79  ? 289 TYR   C CE1 1 
ATOM   3766 C CE2 . TYR   B 2 307 ? 110.689 144.609 109.142 1.00 51.79  ? 289 TYR   C CE2 1 
ATOM   3767 C CZ  . TYR   B 2 307 ? 110.140 145.847 109.250 1.00 51.79  ? 289 TYR   C CZ  1 
ATOM   3768 O OH  . TYR   B 2 307 ? 109.053 146.183 108.484 1.00 51.79  ? 289 TYR   C OH  1 
ATOM   3769 N N   . ASP   B 2 308 ? 116.149 145.553 112.640 1.00 56.71  ? 290 ASP   C N   1 
ATOM   3770 C CA  . ASP   B 2 308 ? 117.102 145.553 113.739 1.00 56.71  ? 290 ASP   C CA  1 
ATOM   3771 C C   . ASP   B 2 308 ? 116.479 145.165 115.073 1.00 56.71  ? 290 ASP   C C   1 
ATOM   3772 O O   . ASP   B 2 308 ? 117.197 145.085 116.073 1.00 56.71  ? 290 ASP   C O   1 
ATOM   3773 C CB  . ASP   B 2 308 ? 117.767 146.922 113.872 1.00 56.71  ? 290 ASP   C CB  1 
ATOM   3774 C CG  . ASP   B 2 308 ? 118.795 147.174 112.801 1.00 56.71  ? 290 ASP   C CG  1 
ATOM   3775 O OD1 . ASP   B 2 308 ? 119.280 146.191 112.210 1.00 56.71  ? 290 ASP   C OD1 1 
ATOM   3776 O OD2 . ASP   B 2 308 ? 119.121 148.352 112.547 1.00 56.71  ? 290 ASP   C OD2 1 
ATOM   3777 N N   . ASP   B 2 309 ? 115.172 144.918 115.121 1.00 59.20  ? 291 ASP   C N   1 
ATOM   3778 C CA  . ASP   B 2 309 ? 114.557 144.388 116.328 1.00 59.20  ? 291 ASP   C CA  1 
ATOM   3779 C C   . ASP   B 2 309 ? 114.701 142.885 116.434 1.00 59.20  ? 291 ASP   C C   1 
ATOM   3780 O O   . ASP   B 2 309 ? 113.960 142.250 117.193 1.00 59.20  ? 291 ASP   C O   1 
ATOM   3781 C CB  . ASP   B 2 309 ? 113.083 144.788 116.400 1.00 59.20  ? 291 ASP   C CB  1 
ATOM   3782 C CG  . ASP   B 2 309 ? 112.240 144.098 115.359 1.00 59.20  ? 291 ASP   C CG  1 
ATOM   3783 O OD1 . ASP   B 2 309 ? 112.804 143.634 114.350 1.00 59.20  ? 291 ASP   C OD1 1 
ATOM   3784 O OD2 . ASP   B 2 309 ? 111.008 144.022 115.547 1.00 59.20  ? 291 ASP   C OD2 1 
ATOM   3785 N N   . PHE   B 2 310 ? 115.621 142.321 115.655 1.00 57.06  ? 292 PHE   C N   1 
ATOM   3786 C CA  . PHE   B 2 310 ? 116.049 140.932 115.704 1.00 57.06  ? 292 PHE   C CA  1 
ATOM   3787 C C   . PHE   B 2 310 ? 115.044 139.965 115.092 1.00 57.06  ? 292 PHE   C C   1 
ATOM   3788 O O   . PHE   B 2 310 ? 115.154 138.759 115.325 1.00 57.06  ? 292 PHE   C O   1 
ATOM   3789 C CB  . PHE   B 2 310 ? 116.368 140.477 117.135 1.00 57.06  ? 292 PHE   C CB  1 
ATOM   3790 C CG  . PHE   B 2 310 ? 117.361 141.348 117.864 1.00 57.06  ? 292 PHE   C CG  1 
ATOM   3791 C CD1 . PHE   B 2 310 ? 118.081 142.327 117.210 1.00 57.06  ? 292 PHE   C CD1 1 
ATOM   3792 C CD2 . PHE   B 2 310 ? 117.578 141.164 119.217 1.00 57.06  ? 292 PHE   C CD2 1 
ATOM   3793 C CE1 . PHE   B 2 310 ? 118.987 143.111 117.889 1.00 57.06  ? 292 PHE   C CE1 1 
ATOM   3794 C CE2 . PHE   B 2 310 ? 118.482 141.942 119.901 1.00 57.06  ? 292 PHE   C CE2 1 
ATOM   3795 C CZ  . PHE   B 2 310 ? 119.189 142.918 119.237 1.00 57.06  ? 292 PHE   C CZ  1 
ATOM   3796 N N   . ASN   B 2 311 ? 114.066 140.427 114.314 1.00 57.43  ? 293 ASN   C N   1 
ATOM   3797 C CA  . ASN   B 2 311 ? 113.165 139.482 113.668 1.00 57.43  ? 293 ASN   C CA  1 
ATOM   3798 C C   . ASN   B 2 311 ? 112.700 140.016 112.320 1.00 57.43  ? 293 ASN   C C   1 
ATOM   3799 O O   . ASN   B 2 311 ? 112.802 141.209 112.032 1.00 57.43  ? 293 ASN   C O   1 
ATOM   3800 C CB  . ASN   B 2 311 ? 111.977 139.135 114.574 1.00 57.43  ? 293 ASN   C CB  1 
ATOM   3801 C CG  . ASN   B 2 311 ? 111.154 140.337 114.961 1.00 57.43  ? 293 ASN   C CG  1 
ATOM   3802 O OD1 . ASN   B 2 311 ? 111.280 141.407 114.381 1.00 57.43  ? 293 ASN   C OD1 1 
ATOM   3803 N ND2 . ASN   B 2 311 ? 110.308 140.166 115.966 1.00 57.43  ? 293 ASN   C ND2 1 
ATOM   3804 N N   . CYS   B 2 312 ? 112.194 139.107 111.493 1.00 56.38  ? 294 CYS   C N   1 
ATOM   3805 C CA  . CYS   B 2 312 ? 111.766 139.404 110.133 1.00 56.38  ? 294 CYS   C CA  1 
ATOM   3806 C C   . CYS   B 2 312 ? 110.247 139.419 110.057 1.00 56.38  ? 294 CYS   C C   1 
ATOM   3807 O O   . CYS   B 2 312 ? 109.589 138.496 110.543 1.00 56.38  ? 294 CYS   C O   1 
ATOM   3808 C CB  . CYS   B 2 312 ? 112.329 138.376 109.151 1.00 56.38  ? 294 CYS   C CB  1 
ATOM   3809 S SG  . CYS   B 2 312 ? 111.914 138.687 107.425 1.00 56.38  ? 294 CYS   C SG  1 
ATOM   3810 N N   . ASN   B 2 313 ? 109.696 140.464 109.452 1.00 56.17  ? 295 ASN   C N   1 
ATOM   3811 C CA  . ASN   B 2 313 ? 108.258 140.621 109.299 1.00 56.17  ? 295 ASN   C CA  1 
ATOM   3812 C C   . ASN   B 2 313 ? 107.868 140.321 107.862 1.00 56.17  ? 295 ASN   C C   1 
ATOM   3813 O O   . ASN   B 2 313 ? 108.516 140.796 106.926 1.00 56.17  ? 295 ASN   C O   1 
ATOM   3814 C CB  . ASN   B 2 313 ? 107.814 142.031 109.680 1.00 56.17  ? 295 ASN   C CB  1 
ATOM   3815 C CG  . ASN   B 2 313 ? 108.063 142.347 111.136 1.00 56.17  ? 295 ASN   C CG  1 
ATOM   3816 O OD1 . ASN   B 2 313 ? 107.463 141.744 112.025 1.00 56.17  ? 295 ASN   C OD1 1 
ATOM   3817 N ND2 . ASN   B 2 313 ? 108.961 143.288 111.391 1.00 56.17  ? 295 ASN   C ND2 1 
ATOM   3818 N N   . VAL   B 2 314 ? 106.808 139.544 107.694 1.00 54.66  ? 296 VAL   C N   1 
ATOM   3819 C CA  . VAL   B 2 314 ? 106.385 139.047 106.395 1.00 54.66  ? 296 VAL   C CA  1 
ATOM   3820 C C   . VAL   B 2 314 ? 105.116 139.798 106.019 1.00 54.66  ? 296 VAL   C C   1 
ATOM   3821 O O   . VAL   B 2 314 ? 104.027 139.487 106.507 1.00 54.66  ? 296 VAL   C O   1 
ATOM   3822 C CB  . VAL   B 2 314 ? 106.166 137.534 106.409 1.00 54.66  ? 296 VAL   C CB  1 
ATOM   3823 C CG1 . VAL   B 2 314 ? 105.633 137.074 105.080 1.00 54.66  ? 296 VAL   C CG1 1 
ATOM   3824 C CG2 . VAL   B 2 314 ? 107.461 136.829 106.727 1.00 54.66  ? 296 VAL   C CG2 1 
ATOM   3825 N N   . TRP   B 2 315 ? 105.255 140.787 105.150 1.00 53.13  ? 297 TRP   C N   1 
ATOM   3826 C CA  . TRP   B 2 315 ? 104.142 141.615 104.722 1.00 53.13  ? 297 TRP   C CA  1 
ATOM   3827 C C   . TRP   B 2 315 ? 103.420 140.979 103.544 1.00 53.13  ? 297 TRP   C C   1 
ATOM   3828 O O   . TRP   B 2 315 ? 103.964 140.141 102.824 1.00 53.13  ? 297 TRP   C O   1 
ATOM   3829 C CB  . TRP   B 2 315 ? 104.623 143.010 104.329 1.00 53.13  ? 297 TRP   C CB  1 
ATOM   3830 C CG  . TRP   B 2 315 ? 105.411 143.721 105.374 1.00 53.13  ? 297 TRP   C CG  1 
ATOM   3831 C CD1 . TRP   B 2 315 ? 106.742 143.615 105.599 1.00 53.13  ? 297 TRP   C CD1 1 
ATOM   3832 C CD2 . TRP   B 2 315 ? 104.919 144.671 106.318 1.00 53.13  ? 297 TRP   C CD2 1 
ATOM   3833 N NE1 . TRP   B 2 315 ? 107.111 144.426 106.635 1.00 53.13  ? 297 TRP   C NE1 1 
ATOM   3834 C CE2 . TRP   B 2 315 ? 106.006 145.089 107.091 1.00 53.13  ? 297 TRP   C CE2 1 
ATOM   3835 C CE3 . TRP   B 2 315 ? 103.660 145.199 106.589 1.00 53.13  ? 297 TRP   C CE3 1 
ATOM   3836 C CZ2 . TRP   B 2 315 ? 105.874 146.003 108.118 1.00 53.13  ? 297 TRP   C CZ2 1 
ATOM   3837 C CZ3 . TRP   B 2 315 ? 103.532 146.101 107.599 1.00 53.13  ? 297 TRP   C CZ3 1 
ATOM   3838 C CH2 . TRP   B 2 315 ? 104.628 146.499 108.353 1.00 53.13  ? 297 TRP   C CH2 1 
ATOM   3839 N N   . ASP   B 2 316 ? 102.178 141.395 103.356 1.00 59.08  ? 298 ASP   C N   1 
ATOM   3840 C CA  . ASP   B 2 316 ? 101.413 141.071 102.163 1.00 59.08  ? 298 ASP   C CA  1 
ATOM   3841 C C   . ASP   B 2 316 ? 101.615 142.208 101.174 1.00 59.08  ? 298 ASP   C C   1 
ATOM   3842 O O   . ASP   B 2 316 ? 101.199 143.340 101.431 1.00 59.08  ? 298 ASP   C O   1 
ATOM   3843 C CB  . ASP   B 2 316 ? 99.941  140.885 102.508 1.00 59.08  ? 298 ASP   C CB  1 
ATOM   3844 C CG  . ASP   B 2 316 ? 99.130  140.416 101.338 1.00 59.08  ? 298 ASP   C CG  1 
ATOM   3845 O OD1 . ASP   B 2 316 ? 99.244  139.229 100.975 1.00 59.08  ? 298 ASP   C OD1 1 
ATOM   3846 O OD2 . ASP   B 2 316 ? 98.375  141.231 100.773 1.00 59.08  ? 298 ASP   C OD2 1 
ATOM   3847 N N   . ALA   B 2 317 ? 102.253 141.907 100.043 1.00 60.82  ? 299 ALA   C N   1 
ATOM   3848 C CA  . ALA   B 2 317 ? 102.737 142.961 99.159  1.00 60.82  ? 299 ALA   C CA  1 
ATOM   3849 C C   . ALA   B 2 317 ? 101.598 143.802 98.608  1.00 60.82  ? 299 ALA   C C   1 
ATOM   3850 O O   . ALA   B 2 317 ? 101.755 145.010 98.401  1.00 60.82  ? 299 ALA   C O   1 
ATOM   3851 C CB  . ALA   B 2 317 ? 103.552 142.360 98.018  1.00 60.82  ? 299 ALA   C CB  1 
ATOM   3852 N N   . LEU   B 2 318 ? 100.449 143.192 98.366  1.00 66.82  ? 300 LEU   C N   1 
ATOM   3853 C CA  . LEU   B 2 318 ? 99.346  143.910 97.756  1.00 66.82  ? 300 LEU   C CA  1 
ATOM   3854 C C   . LEU   B 2 318 ? 98.397  144.551 98.762  1.00 66.82  ? 300 LEU   C C   1 
ATOM   3855 O O   . LEU   B 2 318 ? 97.509  145.300 98.349  1.00 66.82  ? 300 LEU   C O   1 
ATOM   3856 C CB  . LEU   B 2 318 ? 98.563  142.971 96.841  1.00 66.82  ? 300 LEU   C CB  1 
ATOM   3857 C CG  . LEU   B 2 318 ? 99.324  142.560 95.585  1.00 66.82  ? 300 LEU   C CG  1 
ATOM   3858 C CD1 . LEU   B 2 318 ? 98.643  141.384 94.911  1.00 66.82  ? 300 LEU   C CD1 1 
ATOM   3859 C CD2 . LEU   B 2 318 ? 99.443  143.732 94.634  1.00 66.82  ? 300 LEU   C CD2 1 
ATOM   3860 N N   . LYS   B 2 319 ? 98.556  144.300 100.062 1.00 67.22  ? 301 LYS   C N   1 
ATOM   3861 C CA  . LYS   B 2 319 ? 97.597  144.834 101.020 1.00 67.22  ? 301 LYS   C CA  1 
ATOM   3862 C C   . LYS   B 2 319 ? 98.216  145.347 102.317 1.00 67.22  ? 301 LYS   C C   1 
ATOM   3863 O O   . LYS   B 2 319 ? 97.468  145.707 103.232 1.00 67.22  ? 301 LYS   C O   1 
ATOM   3864 C CB  . LYS   B 2 319 ? 96.536  143.782 101.343 1.00 67.22  ? 301 LYS   C CB  1 
ATOM   3865 C CG  . LYS   B 2 319 ? 95.381  143.762 100.362 1.00 67.22  ? 301 LYS   C CG  1 
ATOM   3866 C CD  . LYS   B 2 319 ? 94.360  142.709 100.743 1.00 67.22  ? 301 LYS   C CD  1 
ATOM   3867 C CE  . LYS   B 2 319 ? 93.450  143.202 101.852 1.00 67.22  ? 301 LYS   C CE  1 
ATOM   3868 N NZ  . LYS   B 2 319 ? 92.509  144.245 101.365 1.00 67.22  ? 301 LYS   C NZ  1 
ATOM   3869 N N   . ALA   B 2 320 ? 99.542  145.386 102.430 1.00 61.65  ? 302 ALA   C N   1 
ATOM   3870 C CA  . ALA   B 2 320 ? 100.239 146.080 103.519 1.00 61.65  ? 302 ALA   C CA  1 
ATOM   3871 C C   . ALA   B 2 320 ? 99.785  145.623 104.902 1.00 61.65  ? 302 ALA   C C   1 
ATOM   3872 O O   . ALA   B 2 320 ? 99.622  146.432 105.815 1.00 61.65  ? 302 ALA   C O   1 
ATOM   3873 C CB  . ALA   B 2 320 ? 100.086 147.592 103.386 1.00 61.65  ? 302 ALA   C CB  1 
ATOM   3874 N N   . ASP   B 2 321 ? 99.590  144.323 105.068 1.00 61.38  ? 303 ASP   C N   1 
ATOM   3875 C CA  . ASP   B 2 321 ? 99.260  143.747 106.361 1.00 61.38  ? 303 ASP   C CA  1 
ATOM   3876 C C   . ASP   B 2 321 ? 100.276 142.672 106.697 1.00 61.38  ? 303 ASP   C C   1 
ATOM   3877 O O   . ASP   B 2 321 ? 100.675 141.891 105.829 1.00 61.38  ? 303 ASP   C O   1 
ATOM   3878 C CB  . ASP   B 2 321 ? 97.854  143.150 106.372 1.00 61.38  ? 303 ASP   C CB  1 
ATOM   3879 N N   . ARG   B 2 322 ? 100.695 142.640 107.952 1.00 60.99  ? 304 ARG   C N   1 
ATOM   3880 C CA  . ARG   B 2 322 ? 101.618 141.612 108.392 1.00 60.99  ? 304 ARG   C CA  1 
ATOM   3881 C C   . ARG   B 2 322 ? 100.965 140.241 108.312 1.00 60.99  ? 304 ARG   C C   1 
ATOM   3882 O O   . ARG   B 2 322 ? 99.751  140.093 108.452 1.00 60.99  ? 304 ARG   C O   1 
ATOM   3883 C CB  . ARG   B 2 322 ? 102.080 141.878 109.821 1.00 60.99  ? 304 ARG   C CB  1 
ATOM   3884 C CG  . ARG   B 2 322 ? 103.302 142.758 109.939 1.00 60.99  ? 304 ARG   C CG  1 
ATOM   3885 C CD  . ARG   B 2 322 ? 103.606 143.202 111.378 1.00 60.99  ? 304 ARG   C CD  1 
ATOM   3886 N NE  . ARG   B 2 322 ? 103.868 142.100 112.303 1.00 60.99  ? 304 ARG   C NE  1 
ATOM   3887 C CZ  . ARG   B 2 322 ? 102.937 141.436 112.983 1.00 60.99  ? 304 ARG   C CZ  1 
ATOM   3888 N NH1 . ARG   B 2 322 ? 101.660 141.776 112.884 1.00 60.99  ? 304 ARG   C NH1 1 
ATOM   3889 N NH2 . ARG   B 2 322 ? 103.286 140.446 113.791 1.00 60.99  ? 304 ARG   C NH2 1 
ATOM   3890 N N   . ALA   B 2 323 ? 101.791 139.231 108.081 1.00 61.92  ? 305 ALA   C N   1 
ATOM   3891 C CA  . ALA   B 2 323 ? 101.329 137.859 108.056 1.00 61.92  ? 305 ALA   C CA  1 
ATOM   3892 C C   . ALA   B 2 323 ? 102.073 136.955 109.019 1.00 61.92  ? 305 ALA   C C   1 
ATOM   3893 O O   . ALA   B 2 323 ? 101.619 135.829 109.247 1.00 61.92  ? 305 ALA   C O   1 
ATOM   3894 C CB  . ALA   B 2 323 ? 101.440 137.279 106.639 1.00 61.92  ? 305 ALA   C CB  1 
ATOM   3895 N N   . GLY   B 2 324 ? 103.185 137.395 109.586 1.00 57.66  ? 306 GLY   C N   1 
ATOM   3896 C CA  . GLY   B 2 324 ? 103.919 136.564 110.515 1.00 57.66  ? 306 GLY   C CA  1 
ATOM   3897 C C   . GLY   B 2 324 ? 105.289 137.137 110.774 1.00 57.66  ? 306 GLY   C C   1 
ATOM   3898 O O   . GLY   B 2 324 ? 105.766 138.030 110.071 1.00 57.66  ? 306 GLY   C O   1 
ATOM   3899 N N   . VAL   B 2 325 ? 105.923 136.596 111.806 1.00 53.83  ? 307 VAL   C N   1 
ATOM   3900 C CA  . VAL   B 2 325 ? 107.248 137.017 112.228 1.00 53.83  ? 307 VAL   C CA  1 
ATOM   3901 C C   . VAL   B 2 325 ? 108.143 135.793 112.303 1.00 53.83  ? 307 VAL   C C   1 
ATOM   3902 O O   . VAL   B 2 325 ? 107.754 134.767 112.868 1.00 53.83  ? 307 VAL   C O   1 
ATOM   3903 C CB  . VAL   B 2 325 ? 107.216 137.738 113.585 1.00 53.83  ? 307 VAL   C CB  1 
ATOM   3904 C CG1 . VAL   B 2 325 ? 108.539 138.405 113.847 1.00 53.83  ? 307 VAL   C CG1 1 
ATOM   3905 C CG2 . VAL   B 2 325 ? 106.100 138.753 113.616 1.00 53.83  ? 307 VAL   C CG2 1 
ATOM   3906 N N   . LEU   B 2 326 ? 109.336 135.899 111.724 1.00 54.57  ? 308 LEU   C N   1 
ATOM   3907 C CA  . LEU   B 2 326 ? 110.378 134.892 111.892 1.00 54.57  ? 308 LEU   C CA  1 
ATOM   3908 C C   . LEU   B 2 326 ? 111.268 135.336 113.044 1.00 54.57  ? 308 LEU   C C   1 
ATOM   3909 O O   . LEU   B 2 326 ? 112.376 135.840 112.863 1.00 54.57  ? 308 LEU   C O   1 
ATOM   3910 C CB  . LEU   B 2 326 ? 111.175 134.720 110.609 1.00 54.57  ? 308 LEU   C CB  1 
ATOM   3911 C CG  . LEU   B 2 326 ? 110.369 134.536 109.336 1.00 54.57  ? 308 LEU   C CG  1 
ATOM   3912 C CD1 . LEU   B 2 326 ? 111.290 134.579 108.142 1.00 54.57  ? 308 LEU   C CD1 1 
ATOM   3913 C CD2 . LEU   B 2 326 ? 109.639 133.225 109.411 1.00 54.57  ? 308 LEU   C CD2 1 
ATOM   3914 N N   . ALA   B 2 327 ? 110.766 135.141 114.253 1.00 56.10  ? 309 ALA   C N   1 
ATOM   3915 C CA  . ALA   B 2 327 ? 111.460 135.568 115.462 1.00 56.10  ? 309 ALA   C CA  1 
ATOM   3916 C C   . ALA   B 2 327 ? 112.265 134.390 115.989 1.00 56.10  ? 309 ALA   C C   1 
ATOM   3917 O O   . ALA   B 2 327 ? 111.780 133.589 116.787 1.00 56.10  ? 309 ALA   C O   1 
ATOM   3918 C CB  . ALA   B 2 327 ? 110.471 136.083 116.500 1.00 56.10  ? 309 ALA   C CB  1 
ATOM   3919 N N   . GLY   B 2 328 ? 113.507 134.287 115.540 1.00 55.80  ? 310 GLY   C N   1 
ATOM   3920 C CA  . GLY   B 2 328 ? 114.382 133.256 116.048 1.00 55.80  ? 310 GLY   C CA  1 
ATOM   3921 C C   . GLY   B 2 328 ? 115.818 133.708 116.160 1.00 55.80  ? 310 GLY   C C   1 
ATOM   3922 O O   . GLY   B 2 328 ? 116.729 132.881 116.244 1.00 55.80  ? 310 GLY   C O   1 
ATOM   3923 N N   . HIS   B 2 329 ? 116.037 135.016 116.160 1.00 54.55  ? 311 HIS   C N   1 
ATOM   3924 C CA  . HIS   B 2 329 ? 117.374 135.580 116.158 1.00 54.55  ? 311 HIS   C CA  1 
ATOM   3925 C C   . HIS   B 2 329 ? 117.598 136.424 117.403 1.00 54.55  ? 311 HIS   C C   1 
ATOM   3926 O O   . HIS   B 2 329 ? 116.683 137.089 117.897 1.00 54.55  ? 311 HIS   C O   1 
ATOM   3927 C CB  . HIS   B 2 329 ? 117.610 136.432 114.907 1.00 54.55  ? 311 HIS   C CB  1 
ATOM   3928 C CG  . HIS   B 2 329 ? 117.979 135.638 113.696 1.00 54.55  ? 311 HIS   C CG  1 
ATOM   3929 N ND1 . HIS   B 2 329 ? 119.137 134.898 113.617 1.00 54.55  ? 311 HIS   C ND1 1 
ATOM   3930 C CD2 . HIS   B 2 329 ? 117.342 135.468 112.517 1.00 54.55  ? 311 HIS   C CD2 1 
ATOM   3931 C CE1 . HIS   B 2 329 ? 119.198 134.305 112.441 1.00 54.55  ? 311 HIS   C CE1 1 
ATOM   3932 N NE2 . HIS   B 2 329 ? 118.119 134.634 111.754 1.00 54.55  ? 311 HIS   C NE2 1 
ATOM   3933 N N   . ASP   B 2 330 ? 118.827 136.400 117.900 1.00 57.90  ? 312 ASP   C N   1 
ATOM   3934 C CA  . ASP   B 2 330 ? 119.230 137.181 119.058 1.00 57.90  ? 312 ASP   C CA  1 
ATOM   3935 C C   . ASP   B 2 330 ? 120.320 138.184 118.694 1.00 57.90  ? 312 ASP   C C   1 
ATOM   3936 O O   . ASP   B 2 330 ? 121.253 138.430 119.459 1.00 57.90  ? 312 ASP   C O   1 
ATOM   3937 C CB  . ASP   B 2 330 ? 119.652 136.267 120.207 1.00 57.90  ? 312 ASP   C CB  1 
ATOM   3938 C CG  . ASP   B 2 330 ? 120.852 135.414 119.873 1.00 57.90  ? 312 ASP   C CG  1 
ATOM   3939 O OD1 . ASP   B 2 330 ? 121.343 135.491 118.732 1.00 57.90  ? 312 ASP   C OD1 1 
ATOM   3940 O OD2 . ASP   B 2 330 ? 121.305 134.656 120.756 1.00 57.90  ? 312 ASP   C OD2 1 
ATOM   3941 N N   . ASN   B 2 331 ? 120.198 138.760 117.506 1.00 54.22  ? 313 ASN   C N   1 
ATOM   3942 C CA  . ASN   B 2 331 ? 120.949 139.920 117.040 1.00 54.22  ? 313 ASN   C CA  1 
ATOM   3943 C C   . ASN   B 2 331 ? 120.362 140.281 115.684 1.00 54.22  ? 313 ASN   C C   1 
ATOM   3944 O O   . ASN   B 2 331 ? 119.465 139.599 115.182 1.00 54.22  ? 313 ASN   C O   1 
ATOM   3945 C CB  . ASN   B 2 331 ? 122.449 139.657 116.966 1.00 54.22  ? 313 ASN   C CB  1 
ATOM   3946 C CG  . ASN   B 2 331 ? 123.263 140.865 117.351 1.00 54.22  ? 313 ASN   C CG  1 
ATOM   3947 O OD1 . ASN   B 2 331 ? 122.896 141.993 117.040 1.00 54.22  ? 313 ASN   C OD1 1 
ATOM   3948 N ND2 . ASN   B 2 331 ? 124.373 140.638 118.036 1.00 54.22  ? 313 ASN   C ND2 1 
ATOM   3949 N N   . ARG   B 2 332 ? 120.860 141.358 115.092 1.00 51.45  ? 314 ARG   C N   1 
ATOM   3950 C CA  . ARG   B 2 332 ? 120.216 141.877 113.897 1.00 51.45  ? 314 ARG   C CA  1 
ATOM   3951 C C   . ARG   B 2 332 ? 120.398 140.927 112.722 1.00 51.45  ? 314 ARG   C C   1 
ATOM   3952 O O   . ARG   B 2 332 ? 121.375 140.182 112.640 1.00 51.45  ? 314 ARG   C O   1 
ATOM   3953 C CB  . ARG   B 2 332 ? 120.757 143.260 113.548 1.00 51.45  ? 314 ARG   C CB  1 
ATOM   3954 C CG  . ARG   B 2 332 ? 121.951 143.250 112.652 1.00 51.45  ? 314 ARG   C CG  1 
ATOM   3955 C CD  . ARG   B 2 332 ? 122.601 144.600 112.612 1.00 51.45  ? 314 ARG   C CD  1 
ATOM   3956 N NE  . ARG   B 2 332 ? 121.881 145.531 111.760 1.00 51.45  ? 314 ARG   C NE  1 
ATOM   3957 C CZ  . ARG   B 2 332 ? 122.320 145.952 110.580 1.00 51.45  ? 314 ARG   C CZ  1 
ATOM   3958 N NH1 . ARG   B 2 332 ? 123.474 145.513 110.105 1.00 51.45  ? 314 ARG   C NH1 1 
ATOM   3959 N NH2 . ARG   B 2 332 ? 121.601 146.807 109.868 1.00 51.45  ? 314 ARG   C NH2 1 
ATOM   3960 N N   . VAL   B 2 333 ? 119.421 140.938 111.822 1.00 51.10  ? 315 VAL   C N   1 
ATOM   3961 C CA  . VAL   B 2 333 ? 119.496 140.176 110.583 1.00 51.10  ? 315 VAL   C CA  1 
ATOM   3962 C C   . VAL   B 2 333 ? 120.197 141.048 109.549 1.00 51.10  ? 315 VAL   C C   1 
ATOM   3963 O O   . VAL   B 2 333 ? 119.689 142.095 109.152 1.00 51.10  ? 315 VAL   C O   1 
ATOM   3964 C CB  . VAL   B 2 333 ? 118.110 139.728 110.106 1.00 51.10  ? 315 VAL   C CB  1 
ATOM   3965 C CG1 . VAL   B 2 333 ? 117.592 138.638 111.002 1.00 51.10  ? 315 VAL   C CG1 1 
ATOM   3966 C CG2 . VAL   B 2 333 ? 117.139 140.872 110.122 1.00 51.10  ? 315 VAL   C CG2 1 
ATOM   3967 N N   . SER   B 2 334 ? 121.382 140.629 109.128 1.00 52.77  ? 316 SER   C N   1 
ATOM   3968 C CA  . SER   B 2 334 ? 122.177 141.404 108.193 1.00 52.77  ? 316 SER   C CA  1 
ATOM   3969 C C   . SER   B 2 334 ? 121.980 140.982 106.748 1.00 52.77  ? 316 SER   C C   1 
ATOM   3970 O O   . SER   B 2 334 ? 122.520 141.636 105.851 1.00 52.77  ? 316 SER   C O   1 
ATOM   3971 C CB  . SER   B 2 334 ? 123.657 141.287 108.550 1.00 52.77  ? 316 SER   C CB  1 
ATOM   3972 O OG  . SER   B 2 334 ? 124.063 139.931 108.535 1.00 52.77  ? 316 SER   C OG  1 
ATOM   3973 N N   . CYS   B 2 335 ? 121.225 139.920 106.503 1.00 51.47  ? 317 CYS   C N   1 
ATOM   3974 C CA  . CYS   B 2 335 ? 121.138 139.325 105.181 1.00 51.47  ? 317 CYS   C CA  1 
ATOM   3975 C C   . CYS   B 2 335 ? 119.943 138.389 105.138 1.00 51.47  ? 317 CYS   C C   1 
ATOM   3976 O O   . CYS   B 2 335 ? 119.561 137.803 106.152 1.00 51.47  ? 317 CYS   C O   1 
ATOM   3977 C CB  . CYS   B 2 335 ? 122.433 138.592 104.839 1.00 51.47  ? 317 CYS   C CB  1 
ATOM   3978 S SG  . CYS   B 2 335 ? 122.594 137.005 105.650 1.00 51.47  ? 317 CYS   C SG  1 
ATOM   3979 N N   . LEU   B 2 336 ? 119.356 138.265 103.954 1.00 49.08  ? 318 LEU   C N   1 
ATOM   3980 C CA  . LEU   B 2 336 ? 118.080 137.576 103.801 1.00 49.08  ? 318 LEU   C CA  1 
ATOM   3981 C C   . LEU   B 2 336 ? 117.888 137.273 102.328 1.00 49.08  ? 318 LEU   C C   1 
ATOM   3982 O O   . LEU   B 2 336 ? 117.881 138.196 101.507 1.00 49.08  ? 318 LEU   C O   1 
ATOM   3983 C CB  . LEU   B 2 336 ? 116.950 138.449 104.333 1.00 49.08  ? 318 LEU   C CB  1 
ATOM   3984 C CG  . LEU   B 2 336 ? 115.502 138.160 103.982 1.00 49.08  ? 318 LEU   C CG  1 
ATOM   3985 C CD1 . LEU   B 2 336 ? 115.123 136.799 104.489 1.00 49.08  ? 318 LEU   C CD1 1 
ATOM   3986 C CD2 . LEU   B 2 336 ? 114.616 139.211 104.592 1.00 49.08  ? 318 LEU   C CD2 1 
ATOM   3987 N N   . GLY   B 2 337 ? 117.733 136.004 101.989 1.00 47.36  ? 319 GLY   C N   1 
ATOM   3988 C CA  . GLY   B 2 337 ? 117.584 135.608 100.602 1.00 47.36  ? 319 GLY   C CA  1 
ATOM   3989 C C   . GLY   B 2 337 ? 116.492 134.578 100.434 1.00 47.36  ? 319 GLY   C C   1 
ATOM   3990 O O   . GLY   B 2 337 ? 116.215 133.782 101.331 1.00 47.36  ? 319 GLY   C O   1 
ATOM   3991 N N   . VAL   B 2 338 ? 115.883 134.592 99.257  1.00 49.20  ? 320 VAL   C N   1 
ATOM   3992 C CA  . VAL   B 2 338 ? 114.838 133.652 98.879  1.00 49.20  ? 320 VAL   C CA  1 
ATOM   3993 C C   . VAL   B 2 338 ? 115.324 132.857 97.678  1.00 49.20  ? 320 VAL   C C   1 
ATOM   3994 O O   . VAL   B 2 338 ? 115.862 133.432 96.725  1.00 49.20  ? 320 VAL   C O   1 
ATOM   3995 C CB  . VAL   B 2 338 ? 113.521 134.376 98.560  1.00 49.20  ? 320 VAL   C CB  1 
ATOM   3996 C CG1 . VAL   B 2 338 ? 112.480 133.394 98.098  1.00 49.20  ? 320 VAL   C CG1 1 
ATOM   3997 C CG2 . VAL   B 2 338 ? 113.038 135.102 99.777  1.00 49.20  ? 320 VAL   C CG2 1 
ATOM   3998 N N   . THR   B 2 339 ? 115.149 131.541 97.730  1.00 56.76  ? 321 THR   C N   1 
ATOM   3999 C CA  . THR   B 2 339 ? 115.575 130.673 96.644  1.00 56.76  ? 321 THR   C CA  1 
ATOM   4000 C C   . THR   B 2 339 ? 114.877 131.040 95.341  1.00 56.76  ? 321 THR   C C   1 
ATOM   4001 O O   . THR   B 2 339 ? 113.769 131.583 95.333  1.00 56.76  ? 321 THR   C O   1 
ATOM   4002 C CB  . THR   B 2 339 ? 115.280 129.221 96.985  1.00 56.76  ? 321 THR   C CB  1 
ATOM   4003 O OG1 . THR   B 2 339 ? 113.865 129.013 96.980  1.00 56.76  ? 321 THR   C OG1 1 
ATOM   4004 C CG2 . THR   B 2 339 ? 115.811 128.887 98.342  1.00 56.76  ? 321 THR   C CG2 1 
ATOM   4005 N N   . ASP   B 2 340 ? 115.541 130.735 94.224  1.00 63.88  ? 322 ASP   C N   1 
ATOM   4006 C CA  . ASP   B 2 340 ? 114.985 131.049 92.915  1.00 63.88  ? 322 ASP   C CA  1 
ATOM   4007 C C   . ASP   B 2 340 ? 113.769 130.198 92.585  1.00 63.88  ? 322 ASP   C C   1 
ATOM   4008 O O   . ASP   B 2 340 ? 113.025 130.537 91.660  1.00 63.88  ? 322 ASP   C O   1 
ATOM   4009 C CB  . ASP   B 2 340 ? 116.048 130.874 91.833  1.00 63.88  ? 322 ASP   C CB  1 
ATOM   4010 C CG  . ASP   B 2 340 ? 117.104 131.961 91.873  1.00 63.88  ? 322 ASP   C CG  1 
ATOM   4011 O OD1 . ASP   B 2 340 ? 116.779 133.094 92.285  1.00 63.88  ? 322 ASP   C OD1 1 
ATOM   4012 O OD2 . ASP   B 2 340 ? 118.261 131.683 91.492  1.00 63.88  ? 322 ASP   C OD2 1 
ATOM   4013 N N   . ASP   B 2 341 ? 113.550 129.106 93.313  1.00 66.59  ? 323 ASP   C N   1 
ATOM   4014 C CA  . ASP   B 2 341 ? 112.358 128.291 93.155  1.00 66.59  ? 323 ASP   C CA  1 
ATOM   4015 C C   . ASP   B 2 341 ? 111.358 128.480 94.287  1.00 66.59  ? 323 ASP   C C   1 
ATOM   4016 O O   . ASP   B 2 341 ? 110.262 127.915 94.228  1.00 66.59  ? 323 ASP   C O   1 
ATOM   4017 C CB  . ASP   B 2 341 ? 112.737 126.813 93.037  1.00 66.59  ? 323 ASP   C CB  1 
ATOM   4018 C CG  . ASP   B 2 341 ? 113.513 126.312 94.232  1.00 66.59  ? 323 ASP   C CG  1 
ATOM   4019 O OD1 . ASP   B 2 341 ? 113.865 127.131 95.102  1.00 66.59  ? 323 ASP   C OD1 1 
ATOM   4020 O OD2 . ASP   B 2 341 ? 113.772 125.094 94.303  1.00 66.59  ? 323 ASP   C OD2 1 
ATOM   4021 N N   . GLY   B 2 342 ? 111.704 129.255 95.309  1.00 64.74  ? 324 GLY   C N   1 
ATOM   4022 C CA  . GLY   B 2 342 ? 110.757 129.640 96.333  1.00 64.74  ? 324 GLY   C CA  1 
ATOM   4023 C C   . GLY   B 2 342 ? 110.558 128.655 97.458  1.00 64.74  ? 324 GLY   C C   1 
ATOM   4024 O O   . GLY   B 2 342 ? 109.641 128.846 98.264  1.00 64.74  ? 324 GLY   C O   1 
ATOM   4025 N N   . MET   B 2 343 ? 111.378 127.613 97.548  1.00 65.96  ? 325 MET   C N   1 
ATOM   4026 C CA  . MET   B 2 343 ? 111.164 126.606 98.578  1.00 65.96  ? 325 MET   C CA  1 
ATOM   4027 C C   . MET   B 2 343 ? 111.497 127.145 99.960  1.00 65.96  ? 325 MET   C C   1 
ATOM   4028 O O   . MET   B 2 343 ? 110.726 126.965 100.908 1.00 65.96  ? 325 MET   C O   1 
ATOM   4029 C CB  . MET   B 2 343 ? 111.993 125.360 98.277  1.00 65.96  ? 325 MET   C CB  1 
ATOM   4030 C CG  . MET   B 2 343 ? 111.387 124.449 97.225  1.00 65.96  ? 325 MET   C CG  1 
ATOM   4031 S SD  . MET   B 2 343 ? 109.702 123.951 97.624  1.00 65.96  ? 325 MET   C SD  1 
ATOM   4032 C CE  . MET   B 2 343 ? 109.940 123.190 99.228  1.00 65.96  ? 325 MET   C CE  1 
ATOM   4033 N N   . ALA   B 2 344 ? 112.639 127.806 100.099 1.00 55.48  ? 326 ALA   C N   1 
ATOM   4034 C CA  . ALA   B 2 344 ? 113.150 128.183 101.402 1.00 55.48  ? 326 ALA   C CA  1 
ATOM   4035 C C   . ALA   B 2 344 ? 113.569 129.641 101.412 1.00 55.48  ? 326 ALA   C C   1 
ATOM   4036 O O   . ALA   B 2 344 ? 113.705 130.283 100.370 1.00 55.48  ? 326 ALA   C O   1 
ATOM   4037 C CB  . ALA   B 2 344 ? 114.335 127.309 101.812 1.00 55.48  ? 326 ALA   C CB  1 
ATOM   4038 N N   . VAL   B 2 345 ? 113.764 130.155 102.617 1.00 48.55  ? 327 VAL   C N   1 
ATOM   4039 C CA  . VAL   B 2 345 ? 114.298 131.489 102.843 1.00 48.55  ? 327 VAL   C CA  1 
ATOM   4040 C C   . VAL   B 2 345 ? 115.324 131.412 103.964 1.00 48.55  ? 327 VAL   C C   1 
ATOM   4041 O O   . VAL   B 2 345 ? 115.118 130.709 104.959 1.00 48.55  ? 327 VAL   C O   1 
ATOM   4042 C CB  . VAL   B 2 345 ? 113.177 132.501 103.157 1.00 48.55  ? 327 VAL   C CB  1 
ATOM   4043 C CG1 . VAL   B 2 345 ? 112.470 132.154 104.424 1.00 48.55  ? 327 VAL   C CG1 1 
ATOM   4044 C CG2 . VAL   B 2 345 ? 113.746 133.872 103.273 1.00 48.55  ? 327 VAL   C CG2 1 
ATOM   4045 N N   . ALA   B 2 346 ? 116.442 132.109 103.794 1.00 45.84  ? 328 ALA   C N   1 
ATOM   4046 C CA  . ALA   B 2 346 ? 117.583 132.000 104.693 1.00 45.84  ? 328 ALA   C CA  1 
ATOM   4047 C C   . ALA   B 2 346 ? 117.906 133.358 105.287 1.00 45.84  ? 328 ALA   C C   1 
ATOM   4048 O O   . ALA   B 2 346 ? 118.141 134.320 104.551 1.00 45.84  ? 328 ALA   C O   1 
ATOM   4049 C CB  . ALA   B 2 346 ? 118.800 131.439 103.961 1.00 45.84  ? 328 ALA   C CB  1 
ATOM   4050 N N   . THR   B 2 347 ? 117.920 133.431 106.611 1.00 48.74  ? 329 THR   C N   1 
ATOM   4051 C CA  . THR   B 2 347 ? 118.258 134.640 107.344 1.00 48.74  ? 329 THR   C CA  1 
ATOM   4052 C C   . THR   B 2 347 ? 119.579 134.433 108.060 1.00 48.74  ? 329 THR   C C   1 
ATOM   4053 O O   . THR   B 2 347 ? 119.747 133.447 108.784 1.00 48.74  ? 329 THR   C O   1 
ATOM   4054 C CB  . THR   B 2 347 ? 117.174 134.995 108.360 1.00 48.74  ? 329 THR   C CB  1 
ATOM   4055 O OG1 . THR   B 2 347 ? 116.897 133.854 109.181 1.00 48.74  ? 329 THR   C OG1 1 
ATOM   4056 C CG2 . THR   B 2 347 ? 115.908 135.430 107.669 1.00 48.74  ? 329 THR   C CG2 1 
ATOM   4057 N N   . GLY   B 2 348 ? 120.511 135.349 107.854 1.00 48.90  ? 330 GLY   C N   1 
ATOM   4058 C CA  . GLY   B 2 348 ? 121.790 135.334 108.542 1.00 48.90  ? 330 GLY   C CA  1 
ATOM   4059 C C   . GLY   B 2 348 ? 121.871 136.529 109.472 1.00 48.90  ? 330 GLY   C C   1 
ATOM   4060 O O   . GLY   B 2 348 ? 121.440 137.627 109.120 1.00 48.90  ? 330 GLY   C O   1 
ATOM   4061 N N   . SER   B 2 349 ? 122.419 136.306 110.655 1.00 50.26  ? 331 SER   C N   1 
ATOM   4062 C CA  . SER   B 2 349 ? 122.425 137.311 111.700 1.00 50.26  ? 331 SER   C CA  1 
ATOM   4063 C C   . SER   B 2 349 ? 123.841 137.541 112.190 1.00 50.26  ? 331 SER   C C   1 
ATOM   4064 O O   . SER   B 2 349 ? 124.769 136.798 111.865 1.00 50.26  ? 331 SER   C O   1 
ATOM   4065 C CB  . SER   B 2 349 ? 121.527 136.903 112.870 1.00 50.26  ? 331 SER   C CB  1 
ATOM   4066 N N   . TRP   B 2 350 ? 123.996 138.593 112.983 1.00 50.52  ? 332 TRP   C N   1 
ATOM   4067 C CA  . TRP   B 2 350 ? 125.265 138.895 113.619 1.00 50.52  ? 332 TRP   C CA  1 
ATOM   4068 C C   . TRP   B 2 350 ? 125.600 137.932 114.743 1.00 50.52  ? 332 TRP   C C   1 
ATOM   4069 O O   . TRP   B 2 350 ? 126.702 138.013 115.290 1.00 50.52  ? 332 TRP   C O   1 
ATOM   4070 C CB  . TRP   B 2 350 ? 125.257 140.320 114.156 1.00 50.52  ? 332 TRP   C CB  1 
ATOM   4071 C CG  . TRP   B 2 350 ? 125.513 141.359 113.131 1.00 50.52  ? 332 TRP   C CG  1 
ATOM   4072 C CD1 . TRP   B 2 350 ? 125.601 141.179 111.794 1.00 50.52  ? 332 TRP   C CD1 1 
ATOM   4073 C CD2 . TRP   B 2 350 ? 125.710 142.754 113.363 1.00 50.52  ? 332 TRP   C CD2 1 
ATOM   4074 N NE1 . TRP   B 2 350 ? 125.840 142.373 111.173 1.00 50.52  ? 332 TRP   C NE1 1 
ATOM   4075 C CE2 . TRP   B 2 350 ? 125.910 143.357 112.119 1.00 50.52  ? 332 TRP   C CE2 1 
ATOM   4076 C CE3 . TRP   B 2 350 ? 125.733 143.548 114.506 1.00 50.52  ? 332 TRP   C CE3 1 
ATOM   4077 C CZ2 . TRP   B 2 350 ? 126.136 144.717 111.982 1.00 50.52  ? 332 TRP   C CZ2 1 
ATOM   4078 C CZ3 . TRP   B 2 350 ? 125.951 144.892 114.370 1.00 50.52  ? 332 TRP   C CZ3 1 
ATOM   4079 C CH2 . TRP   B 2 350 ? 126.151 145.467 113.120 1.00 50.52  ? 332 TRP   C CH2 1 
ATOM   4080 N N   . ASP   B 2 351 ? 124.688 137.042 115.112 1.00 54.65  ? 333 ASP   C N   1 
ATOM   4081 C CA  . ASP   B 2 351 ? 124.971 136.019 116.105 1.00 54.65  ? 333 ASP   C CA  1 
ATOM   4082 C C   . ASP   B 2 351 ? 125.728 134.835 115.529 1.00 54.65  ? 333 ASP   C C   1 
ATOM   4083 O O   . ASP   B 2 351 ? 125.960 133.863 116.254 1.00 54.65  ? 333 ASP   C O   1 
ATOM   4084 C CB  . ASP   B 2 351 ? 123.676 135.533 116.754 1.00 54.65  ? 333 ASP   C CB  1 
ATOM   4085 C CG  . ASP   B 2 351 ? 122.733 134.869 115.769 1.00 54.65  ? 333 ASP   C CG  1 
ATOM   4086 O OD1 . ASP   B 2 351 ? 123.051 134.811 114.564 1.00 54.65  ? 333 ASP   C OD1 1 
ATOM   4087 O OD2 . ASP   B 2 351 ? 121.664 134.396 116.205 1.00 54.65  ? 333 ASP   C OD2 1 
ATOM   4088 N N   . SER   B 2 352 ? 126.075 134.884 114.244 1.00 53.69  ? 334 SER   C N   1 
ATOM   4089 C CA  . SER   B 2 352 ? 126.899 133.872 113.586 1.00 53.69  ? 334 SER   C CA  1 
ATOM   4090 C C   . SER   B 2 352 ? 126.150 132.556 113.393 1.00 53.69  ? 334 SER   C C   1 
ATOM   4091 O O   . SER   B 2 352 ? 126.732 131.479 113.512 1.00 53.69  ? 334 SER   C O   1 
ATOM   4092 C CB  . SER   B 2 352 ? 128.204 133.641 114.344 1.00 53.69  ? 334 SER   C CB  1 
ATOM   4093 O OG  . SER   B 2 352 ? 127.997 132.802 115.465 1.00 53.69  ? 334 SER   C OG  1 
ATOM   4094 N N   . PHE   B 2 353 ? 124.858 132.635 113.091 1.00 52.96  ? 335 PHE   C N   1 
ATOM   4095 C CA  . PHE   B 2 353 ? 124.080 131.454 112.745 1.00 52.96  ? 335 PHE   C CA  1 
ATOM   4096 C C   . PHE   B 2 353 ? 123.195 131.777 111.556 1.00 52.96  ? 335 PHE   C C   1 
ATOM   4097 O O   . PHE   B 2 353 ? 122.455 132.763 111.584 1.00 52.96  ? 335 PHE   C O   1 
ATOM   4098 C CB  . PHE   B 2 353 ? 123.213 130.974 113.918 1.00 52.96  ? 335 PHE   C CB  1 
ATOM   4099 C CG  . PHE   B 2 353 ? 123.994 130.482 115.092 1.00 52.96  ? 335 PHE   C CG  1 
ATOM   4100 C CD1 . PHE   B 2 353 ? 124.655 129.274 115.046 1.00 52.96  ? 335 PHE   C CD1 1 
ATOM   4101 C CD2 . PHE   B 2 353 ? 124.080 131.241 116.241 1.00 52.96  ? 335 PHE   C CD2 1 
ATOM   4102 C CE1 . PHE   B 2 353 ? 125.379 128.826 116.130 1.00 52.96  ? 335 PHE   C CE1 1 
ATOM   4103 C CE2 . PHE   B 2 353 ? 124.800 130.801 117.327 1.00 52.96  ? 335 PHE   C CE2 1 
ATOM   4104 C CZ  . PHE   B 2 353 ? 125.452 129.591 117.272 1.00 52.96  ? 335 PHE   C CZ  1 
ATOM   4105 N N   . LEU   B 2 354 ? 123.273 130.957 110.517 1.00 49.72  ? 336 LEU   C N   1 
ATOM   4106 C CA  . LEU   B 2 354 ? 122.299 130.984 109.440 1.00 49.72  ? 336 LEU   C CA  1 
ATOM   4107 C C   . LEU   B 2 354 ? 121.104 130.133 109.824 1.00 49.72  ? 336 LEU   C C   1 
ATOM   4108 O O   . LEU   B 2 354 ? 121.216 129.198 110.621 1.00 49.72  ? 336 LEU   C O   1 
ATOM   4109 C CB  . LEU   B 2 354 ? 122.891 130.466 108.130 1.00 49.72  ? 336 LEU   C CB  1 
ATOM   4110 C CG  . LEU   B 2 354 ? 123.971 131.259 107.403 1.00 49.72  ? 336 LEU   C CG  1 
ATOM   4111 C CD1 . LEU   B 2 354 ? 124.508 130.453 106.259 1.00 49.72  ? 336 LEU   C CD1 1 
ATOM   4112 C CD2 . LEU   B 2 354 ? 123.385 132.541 106.872 1.00 49.72  ? 336 LEU   C CD2 1 
ATOM   4113 N N   . LYS   B 2 355 ? 119.957 130.453 109.245 1.00 50.35  ? 337 LYS   C N   1 
ATOM   4114 C CA  . LYS   B 2 355 ? 118.740 129.714 109.514 1.00 50.35  ? 337 LYS   C CA  1 
ATOM   4115 C C   . LYS   B 2 355 ? 117.920 129.632 108.245 1.00 50.35  ? 337 LYS   C C   1 
ATOM   4116 O O   . LYS   B 2 355 ? 117.764 130.627 107.536 1.00 50.35  ? 337 LYS   C O   1 
ATOM   4117 C CB  . LYS   B 2 355 ? 117.920 130.363 110.626 1.00 50.35  ? 337 LYS   C CB  1 
ATOM   4118 C CG  . LYS   B 2 355 ? 118.547 130.240 111.997 1.00 50.35  ? 337 LYS   C CG  1 
ATOM   4119 C CD  . LYS   B 2 355 ? 117.515 130.240 113.082 1.00 50.35  ? 337 LYS   C CD  1 
ATOM   4120 C CE  . LYS   B 2 355 ? 118.132 129.843 114.399 1.00 50.35  ? 337 LYS   C CE  1 
ATOM   4121 N NZ  . LYS   B 2 355 ? 119.240 130.754 114.778 1.00 50.35  ? 337 LYS   C NZ  1 
ATOM   4122 N N   . ILE   B 2 356 ? 117.385 128.452 107.974 1.00 50.75  ? 338 ILE   C N   1 
ATOM   4123 C CA  . ILE   B 2 356 ? 116.635 128.184 106.759 1.00 50.75  ? 338 ILE   C CA  1 
ATOM   4124 C C   . ILE   B 2 356 ? 115.194 127.925 107.149 1.00 50.75  ? 338 ILE   C C   1 
ATOM   4125 O O   . ILE   B 2 356 ? 114.921 127.114 108.039 1.00 50.75  ? 338 ILE   C O   1 
ATOM   4126 C CB  . ILE   B 2 356 ? 117.224 126.996 105.979 1.00 50.75  ? 338 ILE   C CB  1 
ATOM   4127 C CG1 . ILE   B 2 356 ? 118.667 127.289 105.589 1.00 50.75  ? 338 ILE   C CG1 1 
ATOM   4128 C CG2 . ILE   B 2 356 ? 116.394 126.705 104.749 1.00 50.75  ? 338 ILE   C CG2 1 
ATOM   4129 C CD1 . ILE   B 2 356 ? 119.231 126.308 104.617 1.00 50.75  ? 338 ILE   C CD1 1 
ATOM   4130 N N   . TRP   B 2 357 ? 114.280 128.607 106.480 1.00 51.91  ? 339 TRP   C N   1 
ATOM   4131 C CA  . TRP   B 2 357 ? 112.887 128.677 106.875 1.00 51.91  ? 339 TRP   C CA  1 
ATOM   4132 C C   . TRP   B 2 357 ? 112.044 128.176 105.714 1.00 51.91  ? 339 TRP   C C   1 
ATOM   4133 O O   . TRP   B 2 357 ? 112.319 128.503 104.558 1.00 51.91  ? 339 TRP   C O   1 
ATOM   4134 C CB  . TRP   B 2 357 ? 112.511 130.118 107.215 1.00 51.91  ? 339 TRP   C CB  1 
ATOM   4135 C CG  . TRP   B 2 357 ? 113.379 130.763 108.248 1.00 51.91  ? 339 TRP   C CG  1 
ATOM   4136 C CD1 . TRP   B 2 357 ? 114.599 131.314 108.037 1.00 51.91  ? 339 TRP   C CD1 1 
ATOM   4137 C CD2 . TRP   B 2 357 ? 113.066 131.005 109.624 1.00 51.91  ? 339 TRP   C CD2 1 
ATOM   4138 N NE1 . TRP   B 2 357 ? 115.093 131.841 109.199 1.00 51.91  ? 339 TRP   C NE1 1 
ATOM   4139 C CE2 . TRP   B 2 357 ? 114.169 131.663 110.190 1.00 51.91  ? 339 TRP   C CE2 1 
ATOM   4140 C CE3 . TRP   B 2 357 ? 111.975 130.704 110.437 1.00 51.91  ? 339 TRP   C CE3 1 
ATOM   4141 C CZ2 . TRP   B 2 357 ? 114.210 132.029 111.526 1.00 51.91  ? 339 TRP   C CZ2 1 
ATOM   4142 C CZ3 . TRP   B 2 357 ? 112.017 131.071 111.758 1.00 51.91  ? 339 TRP   C CZ3 1 
ATOM   4143 C CH2 . TRP   B 2 357 ? 113.125 131.724 112.293 1.00 51.91  ? 339 TRP   C CH2 1 
ATOM   4144 N N   . ASN   B 2 358 ? 111.023 127.385 106.008 1.00 63.15  ? 340 ASN   C N   1 
ATOM   4145 C CA  . ASN   B 2 358 ? 110.190 126.840 104.946 1.00 63.15  ? 340 ASN   C CA  1 
ATOM   4146 C C   . ASN   B 2 358 ? 108.784 126.596 105.472 1.00 63.15  ? 340 ASN   C C   1 
ATOM   4147 O O   . ASN   B 2 358 ? 107.801 126.981 104.844 1.00 63.15  ? 340 ASN   C O   1 
ATOM   4148 C CB  . ASN   B 2 358 ? 110.807 125.551 104.401 1.00 63.15  ? 340 ASN   C CB  1 
ATOM   4149 C CG  . ASN   B 2 358 ? 110.038 124.964 103.225 1.00 63.15  ? 340 ASN   C CG  1 
ATOM   4150 O OD1 . ASN   B 2 358 ? 108.844 125.199 103.049 1.00 63.15  ? 340 ASN   C OD1 1 
ATOM   4151 N ND2 . ASN   B 2 358 ? 110.737 124.188 102.409 1.00 63.15  ? 340 ASN   C ND2 1 
ATOM   4152 O OXT . ASN   B 2 358 ? 108.598 126.008 106.537 1.00 63.15  ? 340 ASN   C OXT 1 
ATOM   4153 N N   . GLN   C 3 11  ? 129.178 175.110 85.812  1.00 138.99 ? 11  GLN   D N   1 
ATOM   4154 C CA  . GLN   C 3 11  ? 128.877 174.241 84.681  1.00 138.99 ? 11  GLN   D CA  1 
ATOM   4155 C C   . GLN   C 3 11  ? 128.216 172.949 85.148  1.00 138.99 ? 11  GLN   D C   1 
ATOM   4156 O O   . GLN   C 3 11  ? 128.800 171.870 85.049  1.00 138.99 ? 11  GLN   D O   1 
ATOM   4157 C CB  . GLN   C 3 11  ? 130.149 173.927 83.890  1.00 138.99 ? 11  GLN   D CB  1 
ATOM   4158 N N   . ALA   C 3 12  ? 126.992 173.067 85.655  1.00 136.90 ? 12  ALA   D N   1 
ATOM   4159 C CA  . ALA   C 3 12  ? 126.222 171.934 86.157  1.00 136.90 ? 12  ALA   D CA  1 
ATOM   4160 C C   . ALA   C 3 12  ? 125.058 171.601 85.230  1.00 136.90 ? 12  ALA   D C   1 
ATOM   4161 O O   . ALA   C 3 12  ? 123.956 171.278 85.678  1.00 136.90 ? 12  ALA   D O   1 
ATOM   4162 C CB  . ALA   C 3 12  ? 125.719 172.205 87.572  1.00 136.90 ? 12  ALA   D CB  1 
ATOM   4163 N N   . ARG   C 3 13  ? 125.294 171.680 83.919  1.00 132.47 ? 13  ARG   D N   1 
ATOM   4164 C CA  . ARG   C 3 13  ? 124.259 171.370 82.939  1.00 132.47 ? 13  ARG   D CA  1 
ATOM   4165 C C   . ARG   C 3 13  ? 123.895 169.892 82.909  1.00 132.47 ? 13  ARG   D C   1 
ATOM   4166 O O   . ARG   C 3 13  ? 122.889 169.532 82.289  1.00 132.47 ? 13  ARG   D O   1 
ATOM   4167 C CB  . ARG   C 3 13  ? 124.706 171.819 81.547  1.00 132.47 ? 13  ARG   D CB  1 
ATOM   4168 N N   . LYS   C 3 14  ? 124.684 169.032 83.558  1.00 129.88 ? 14  LYS   D N   1 
ATOM   4169 C CA  . LYS   C 3 14  ? 124.369 167.608 83.571  1.00 129.88 ? 14  LYS   D CA  1 
ATOM   4170 C C   . LYS   C 3 14  ? 123.038 167.343 84.262  1.00 129.88 ? 14  LYS   D C   1 
ATOM   4171 O O   . LYS   C 3 14  ? 122.241 166.521 83.795  1.00 129.88 ? 14  LYS   D O   1 
ATOM   4172 C CB  . LYS   C 3 14  ? 125.494 166.829 84.252  1.00 129.88 ? 14  LYS   D CB  1 
ATOM   4173 N N   . LEU   C 3 15  ? 122.777 168.035 85.374  1.00 128.11 ? 15  LEU   D N   1 
ATOM   4174 C CA  . LEU   C 3 15  ? 121.543 167.806 86.119  1.00 128.11 ? 15  LEU   D CA  1 
ATOM   4175 C C   . LEU   C 3 15  ? 120.320 168.193 85.297  1.00 128.11 ? 15  LEU   D C   1 
ATOM   4176 O O   . LEU   C 3 15  ? 119.346 167.434 85.216  1.00 128.11 ? 15  LEU   D O   1 
ATOM   4177 C CB  . LEU   C 3 15  ? 121.575 168.582 87.435  1.00 128.11 ? 15  LEU   D CB  1 
ATOM   4178 N N   . VAL   C 3 16  ? 120.352 169.373 84.673  1.00 127.26 ? 16  VAL   D N   1 
ATOM   4179 C CA  . VAL   C 3 16  ? 119.202 169.813 83.889  1.00 127.26 ? 16  VAL   D CA  1 
ATOM   4180 C C   . VAL   C 3 16  ? 119.046 168.955 82.640  1.00 127.26 ? 16  VAL   D C   1 
ATOM   4181 O O   . VAL   C 3 16  ? 117.923 168.665 82.211  1.00 127.26 ? 16  VAL   D O   1 
ATOM   4182 C CB  . VAL   C 3 16  ? 119.310 171.312 83.549  1.00 127.26 ? 16  VAL   D CB  1 
ATOM   4183 C CG1 . VAL   C 3 16  ? 119.037 172.156 84.786  1.00 127.26 ? 16  VAL   D CG1 1 
ATOM   4184 C CG2 . VAL   C 3 16  ? 120.669 171.642 82.968  1.00 127.26 ? 16  VAL   D CG2 1 
ATOM   4185 N N   . GLU   C 3 17  ? 120.160 168.531 82.036  1.00 122.77 ? 17  GLU   D N   1 
ATOM   4186 C CA  . GLU   C 3 17  ? 120.071 167.644 80.880  1.00 122.77 ? 17  GLU   D CA  1 
ATOM   4187 C C   . GLU   C 3 17  ? 119.430 166.314 81.257  1.00 122.77 ? 17  GLU   D C   1 
ATOM   4188 O O   . GLU   C 3 17  ? 118.575 165.796 80.526  1.00 122.77 ? 17  GLU   D O   1 
ATOM   4189 C CB  . GLU   C 3 17  ? 121.458 167.421 80.278  1.00 122.77 ? 17  GLU   D CB  1 
ATOM   4190 N N   . GLN   C 3 18  ? 119.821 165.750 82.402  1.00 113.62 ? 18  GLN   D N   1 
ATOM   4191 C CA  . GLN   C 3 18  ? 119.219 164.503 82.857  1.00 113.62 ? 18  GLN   D CA  1 
ATOM   4192 C C   . GLN   C 3 18  ? 117.741 164.685 83.170  1.00 113.62 ? 18  GLN   D C   1 
ATOM   4193 O O   . GLN   C 3 18  ? 116.922 163.817 82.853  1.00 113.62 ? 18  GLN   D O   1 
ATOM   4194 C CB  . GLN   C 3 18  ? 119.964 163.976 84.081  1.00 113.62 ? 18  GLN   D CB  1 
ATOM   4195 C CG  . GLN   C 3 18  ? 119.424 162.662 84.605  1.00 113.62 ? 18  GLN   D CG  1 
ATOM   4196 C CD  . GLN   C 3 18  ? 119.568 161.541 83.600  1.00 113.62 ? 18  GLN   D CD  1 
ATOM   4197 O OE1 . GLN   C 3 18  ? 120.560 161.465 82.875  1.00 113.62 ? 18  GLN   D OE1 1 
ATOM   4198 N NE2 . GLN   C 3 18  ? 118.575 160.661 83.549  1.00 113.62 ? 18  GLN   D NE2 1 
ATOM   4199 N N   . LEU   C 3 19  ? 117.381 165.805 83.803  1.00 119.76 ? 19  LEU   D N   1 
ATOM   4200 C CA  . LEU   C 3 19  ? 115.975 166.058 84.100  1.00 119.76 ? 19  LEU   D CA  1 
ATOM   4201 C C   . LEU   C 3 19  ? 115.156 166.191 82.822  1.00 119.76 ? 19  LEU   D C   1 
ATOM   4202 O O   . LEU   C 3 19  ? 114.020 165.710 82.751  1.00 119.76 ? 19  LEU   D O   1 
ATOM   4203 C CB  . LEU   C 3 19  ? 115.834 167.309 84.962  1.00 119.76 ? 19  LEU   D CB  1 
ATOM   4204 C CG  . LEU   C 3 19  ? 115.716 167.067 86.465  1.00 119.76 ? 19  LEU   D CG  1 
ATOM   4205 C CD1 . LEU   C 3 19  ? 115.677 168.384 87.221  1.00 119.76 ? 19  LEU   D CD1 1 
ATOM   4206 C CD2 . LEU   C 3 19  ? 114.490 166.232 86.772  1.00 119.76 ? 19  LEU   D CD2 1 
ATOM   4207 N N   . LYS   C 3 20  ? 115.714 166.847 81.802  1.00 118.60 ? 20  LYS   D N   1 
ATOM   4208 C CA  . LYS   C 3 20  ? 115.020 166.968 80.525  1.00 118.60 ? 20  LYS   D CA  1 
ATOM   4209 C C   . LYS   C 3 20  ? 114.878 165.615 79.838  1.00 118.60 ? 20  LYS   D C   1 
ATOM   4210 O O   . LYS   C 3 20  ? 113.850 165.337 79.211  1.00 118.60 ? 20  LYS   D O   1 
ATOM   4211 C CB  . LYS   C 3 20  ? 115.756 167.954 79.619  1.00 118.60 ? 20  LYS   D CB  1 
ATOM   4212 N N   . MET   C 3 21  ? 115.902 164.765 79.934  1.00 113.90 ? 21  MET   D N   1 
ATOM   4213 C CA  . MET   C 3 21  ? 115.824 163.444 79.322  1.00 113.90 ? 21  MET   D CA  1 
ATOM   4214 C C   . MET   C 3 21  ? 114.917 162.495 80.096  1.00 113.90 ? 21  MET   D C   1 
ATOM   4215 O O   . MET   C 3 21  ? 114.427 161.518 79.519  1.00 113.90 ? 21  MET   D O   1 
ATOM   4216 C CB  . MET   C 3 21  ? 117.222 162.837 79.199  1.00 113.90 ? 21  MET   D CB  1 
ATOM   4217 N N   . GLU   C 3 22  ? 114.689 162.755 81.383  1.00 106.31 ? 22  GLU   D N   1 
ATOM   4218 C CA  . GLU   C 3 22  ? 113.855 161.889 82.209  1.00 106.31 ? 22  GLU   D CA  1 
ATOM   4219 C C   . GLU   C 3 22  ? 112.389 162.305 82.202  1.00 106.31 ? 22  GLU   D C   1 
ATOM   4220 O O   . GLU   C 3 22  ? 111.504 161.444 82.203  1.00 106.31 ? 22  GLU   D O   1 
ATOM   4221 C CB  . GLU   C 3 22  ? 114.382 161.872 83.646  1.00 106.31 ? 22  GLU   D CB  1 
ATOM   4222 C CG  . GLU   C 3 22  ? 113.536 161.070 84.611  1.00 106.31 ? 22  GLU   D CG  1 
ATOM   4223 C CD  . GLU   C 3 22  ? 113.909 161.317 86.057  1.00 106.31 ? 22  GLU   D CD  1 
ATOM   4224 O OE1 . GLU   C 3 22  ? 115.102 161.567 86.330  1.00 106.31 ? 22  GLU   D OE1 1 
ATOM   4225 O OE2 . GLU   C 3 22  ? 113.010 161.261 86.922  1.00 106.31 ? 22  GLU   D OE2 1 
ATOM   4226 N N   . ALA   C 3 23  ? 112.114 163.611 82.198  1.00 113.56 ? 23  ALA   D N   1 
ATOM   4227 C CA  . ALA   C 3 23  ? 110.732 164.079 82.209  1.00 113.56 ? 23  ALA   D CA  1 
ATOM   4228 C C   . ALA   C 3 23  ? 110.002 163.684 80.933  1.00 113.56 ? 23  ALA   D C   1 
ATOM   4229 O O   . ALA   C 3 23  ? 108.803 163.382 80.965  1.00 113.56 ? 23  ALA   D O   1 
ATOM   4230 C CB  . ALA   C 3 23  ? 110.691 165.594 82.399  1.00 113.56 ? 23  ALA   D CB  1 
ATOM   4231 N N   . ASN   C 3 24  ? 110.703 163.680 79.801  1.00 110.58 ? 24  ASN   D N   1 
ATOM   4232 C CA  . ASN   C 3 24  ? 110.087 163.382 78.509  1.00 110.58 ? 24  ASN   D CA  1 
ATOM   4233 C C   . ASN   C 3 24  ? 110.069 161.875 78.251  1.00 110.58 ? 24  ASN   D C   1 
ATOM   4234 O O   . ASN   C 3 24  ? 110.712 161.358 77.339  1.00 110.58 ? 24  ASN   D O   1 
ATOM   4235 C CB  . ASN   C 3 24  ? 110.815 164.125 77.395  1.00 110.58 ? 24  ASN   D CB  1 
ATOM   4236 N N   . ILE   C 3 25  ? 109.308 161.166 79.086  1.00 104.18 ? 25  ILE   D N   1 
ATOM   4237 C CA  . ILE   C 3 25  ? 109.102 159.736 78.921  1.00 104.18 ? 25  ILE   D CA  1 
ATOM   4238 C C   . ILE   C 3 25  ? 107.611 159.448 79.009  1.00 104.18 ? 25  ILE   D C   1 
ATOM   4239 O O   . ILE   C 3 25  ? 106.825 160.252 79.511  1.00 104.18 ? 25  ILE   D O   1 
ATOM   4240 C CB  . ILE   C 3 25  ? 109.875 158.891 79.958  1.00 104.18 ? 25  ILE   D CB  1 
ATOM   4241 C CG1 . ILE   C 3 25  ? 109.331 159.133 81.365  1.00 104.18 ? 25  ILE   D CG1 1 
ATOM   4242 C CG2 . ILE   C 3 25  ? 111.370 159.177 79.885  1.00 104.18 ? 25  ILE   D CG2 1 
ATOM   4243 C CD1 . ILE   C 3 25  ? 109.580 157.982 82.310  1.00 104.18 ? 25  ILE   D CD1 1 
ATOM   4244 N N   . ASP   C 3 26  ? 107.230 158.283 78.496  1.00 101.83 ? 26  ASP   D N   1 
ATOM   4245 C CA  . ASP   C 3 26  ? 105.830 157.882 78.423  1.00 101.83 ? 26  ASP   D CA  1 
ATOM   4246 C C   . ASP   C 3 26  ? 105.482 157.072 79.665  1.00 101.83 ? 26  ASP   D C   1 
ATOM   4247 O O   . ASP   C 3 26  ? 106.010 155.975 79.869  1.00 101.83 ? 26  ASP   D O   1 
ATOM   4248 C CB  . ASP   C 3 26  ? 105.567 157.079 77.151  1.00 101.83 ? 26  ASP   D CB  1 
ATOM   4249 C CG  . ASP   C 3 26  ? 104.109 156.693 76.997  1.00 101.83 ? 26  ASP   D CG  1 
ATOM   4250 O OD1 . ASP   C 3 26  ? 103.235 157.502 77.374  1.00 101.83 ? 26  ASP   D OD1 1 
ATOM   4251 O OD2 . ASP   C 3 26  ? 103.836 155.581 76.499  1.00 101.83 ? 26  ASP   D OD2 1 
ATOM   4252 N N   . ARG   C 3 27  ? 104.593 157.612 80.489  1.00 94.59  ? 27  ARG   D N   1 
ATOM   4253 C CA  . ARG   C 3 27  ? 104.133 156.931 81.683  1.00 94.59  ? 27  ARG   D CA  1 
ATOM   4254 C C   . ARG   C 3 27  ? 102.834 156.188 81.395  1.00 94.59  ? 27  ARG   D C   1 
ATOM   4255 O O   . ARG   C 3 27  ? 102.279 156.248 80.295  1.00 94.59  ? 27  ARG   D O   1 
ATOM   4256 C CB  . ARG   C 3 27  ? 103.940 157.927 82.823  1.00 94.59  ? 27  ARG   D CB  1 
ATOM   4257 C CG  . ARG   C 3 27  ? 105.228 158.435 83.422  1.00 94.59  ? 27  ARG   D CG  1 
ATOM   4258 C CD  . ARG   C 3 27  ? 105.692 159.698 82.726  1.00 94.59  ? 27  ARG   D CD  1 
ATOM   4259 N NE  . ARG   C 3 27  ? 106.891 160.244 83.349  1.00 94.59  ? 27  ARG   D NE  1 
ATOM   4260 C CZ  . ARG   C 3 27  ? 106.887 160.936 84.480  1.00 94.59  ? 27  ARG   D CZ  1 
ATOM   4261 N NH1 . ARG   C 3 27  ? 105.745 161.165 85.111  1.00 94.59  ? 27  ARG   D NH1 1 
ATOM   4262 N NH2 . ARG   C 3 27  ? 108.026 161.395 84.978  1.00 94.59  ? 27  ARG   D NH2 1 
ATOM   4263 N N   . ILE   C 3 28  ? 102.342 155.470 82.401  1.00 87.33  ? 28  ILE   D N   1 
ATOM   4264 C CA  . ILE   C 3 28  ? 101.028 154.857 82.374  1.00 87.33  ? 28  ILE   D CA  1 
ATOM   4265 C C   . ILE   C 3 28  ? 100.302 155.226 83.663  1.00 87.33  ? 28  ILE   D C   1 
ATOM   4266 O O   . ILE   C 3 28  ? 100.851 155.893 84.538  1.00 87.33  ? 28  ILE   D O   1 
ATOM   4267 C CB  . ILE   C 3 28  ? 101.091 153.328 82.192  1.00 87.33  ? 28  ILE   D CB  1 
ATOM   4268 C CG1 . ILE   C 3 28  ? 101.433 152.642 83.516  1.00 87.33  ? 28  ILE   D CG1 1 
ATOM   4269 C CG2 . ILE   C 3 28  ? 102.084 152.952 81.104  1.00 87.33  ? 28  ILE   D CG2 1 
ATOM   4270 C CD1 . ILE   C 3 28  ? 101.075 151.172 83.549  1.00 87.33  ? 28  ILE   D CD1 1 
ATOM   4271 N N   . LYS   C 3 29  ? 99.053  154.793 83.766  1.00 90.86  ? 29  LYS   D N   1 
ATOM   4272 C CA  . LYS   C 3 29  ? 98.232  155.085 84.928  1.00 90.86  ? 29  LYS   D CA  1 
ATOM   4273 C C   . LYS   C 3 29  ? 98.500  154.088 86.048  1.00 90.86  ? 29  LYS   D C   1 
ATOM   4274 O O   . LYS   C 3 29  ? 98.920  152.953 85.811  1.00 90.86  ? 29  LYS   D O   1 
ATOM   4275 C CB  . LYS   C 3 29  ? 96.750  155.065 84.555  1.00 90.86  ? 29  LYS   D CB  1 
ATOM   4276 C CG  . LYS   C 3 29  ? 96.442  155.762 83.243  1.00 90.86  ? 29  LYS   D CG  1 
ATOM   4277 C CD  . LYS   C 3 29  ? 96.815  157.229 83.302  1.00 90.86  ? 29  LYS   D CD  1 
ATOM   4278 C CE  . LYS   C 3 29  ? 96.495  157.934 81.995  1.00 90.86  ? 29  LYS   D CE  1 
ATOM   4279 N NZ  . LYS   C 3 29  ? 95.031  157.964 81.724  1.00 90.86  ? 29  LYS   D NZ  1 
ATOM   4280 N N   . VAL   C 3 30  ? 98.246  154.530 87.280  1.00 90.45  ? 30  VAL   D N   1 
ATOM   4281 C CA  . VAL   C 3 30  ? 98.532  153.704 88.448  1.00 90.45  ? 30  VAL   D CA  1 
ATOM   4282 C C   . VAL   C 3 30  ? 97.625  152.484 88.480  1.00 90.45  ? 30  VAL   D C   1 
ATOM   4283 O O   . VAL   C 3 30  ? 98.036  151.401 88.913  1.00 90.45  ? 30  VAL   D O   1 
ATOM   4284 C CB  . VAL   C 3 30  ? 98.407  154.539 89.734  1.00 90.45  ? 30  VAL   D CB  1 
ATOM   4285 C CG1 . VAL   C 3 30  ? 98.650  153.677 90.957  1.00 90.45  ? 30  VAL   D CG1 1 
ATOM   4286 C CG2 . VAL   C 3 30  ? 99.383  155.701 89.703  1.00 90.45  ? 30  VAL   D CG2 1 
ATOM   4287 N N   . SER   C 3 31  ? 96.379  152.634 88.029  1.00 90.72  ? 31  SER   D N   1 
ATOM   4288 C CA  . SER   C 3 31  ? 95.448  151.511 88.052  1.00 90.72  ? 31  SER   D CA  1 
ATOM   4289 C C   . SER   C 3 31  ? 95.920  150.379 87.150  1.00 90.72  ? 31  SER   D C   1 
ATOM   4290 O O   . SER   C 3 31  ? 95.832  149.204 87.523  1.00 90.72  ? 31  SER   D O   1 
ATOM   4291 C CB  . SER   C 3 31  ? 94.054  151.981 87.643  1.00 90.72  ? 31  SER   D CB  1 
ATOM   4292 O OG  . SER   C 3 31  ? 93.640  153.083 88.429  1.00 90.72  ? 31  SER   D OG  1 
ATOM   4293 N N   . LYS   C 3 32  ? 96.434  150.710 85.964  1.00 88.75  ? 32  LYS   D N   1 
ATOM   4294 C CA  . LYS   C 3 32  ? 96.907  149.680 85.044  1.00 88.75  ? 32  LYS   D CA  1 
ATOM   4295 C C   . LYS   C 3 32  ? 98.073  148.896 85.638  1.00 88.75  ? 32  LYS   D C   1 
ATOM   4296 O O   . LYS   C 3 32  ? 98.094  147.660 85.597  1.00 88.75  ? 32  LYS   D O   1 
ATOM   4297 C CB  . LYS   C 3 32  ? 97.309  150.316 83.714  1.00 88.75  ? 32  LYS   D CB  1 
ATOM   4298 C CG  . LYS   C 3 32  ? 97.395  149.330 82.560  1.00 88.75  ? 32  LYS   D CG  1 
ATOM   4299 C CD  . LYS   C 3 32  ? 97.804  150.017 81.267  1.00 88.75  ? 32  LYS   D CD  1 
ATOM   4300 C CE  . LYS   C 3 32  ? 96.864  151.162 80.925  1.00 88.75  ? 32  LYS   D CE  1 
ATOM   4301 N NZ  . LYS   C 3 32  ? 97.160  151.738 79.584  1.00 88.75  ? 32  LYS   D NZ  1 
ATOM   4302 N N   . ALA   C 3 33  ? 99.050  149.600 86.210  1.00 83.50  ? 33  ALA   D N   1 
ATOM   4303 C CA  . ALA   C 3 33  ? 100.208 148.922 86.782  1.00 83.50  ? 33  ALA   D CA  1 
ATOM   4304 C C   . ALA   C 3 33  ? 99.843  148.130 88.034  1.00 83.50  ? 33  ALA   D C   1 
ATOM   4305 O O   . ALA   C 3 33  ? 100.380 147.035 88.258  1.00 83.50  ? 33  ALA   D O   1 
ATOM   4306 C CB  . ALA   C 3 33  ? 101.299 149.942 87.080  1.00 83.50  ? 33  ALA   D CB  1 
ATOM   4307 N N   . ALA   C 3 34  ? 98.939  148.659 88.858  1.00 81.32  ? 34  ALA   D N   1 
ATOM   4308 C CA  . ALA   C 3 34  ? 98.469  147.908 90.015  1.00 81.32  ? 34  ALA   D CA  1 
ATOM   4309 C C   . ALA   C 3 34  ? 97.745  146.641 89.587  1.00 81.32  ? 34  ALA   D C   1 
ATOM   4310 O O   . ALA   C 3 34  ? 97.911  145.583 90.205  1.00 81.32  ? 34  ALA   D O   1 
ATOM   4311 C CB  . ALA   C 3 34  ? 97.559  148.781 90.872  1.00 81.32  ? 34  ALA   D CB  1 
ATOM   4312 N N   . ALA   C 3 35  ? 96.932  146.728 88.534  1.00 80.23  ? 35  ALA   D N   1 
ATOM   4313 C CA  . ALA   C 3 35  ? 96.277  145.537 88.011  1.00 80.23  ? 35  ALA   D CA  1 
ATOM   4314 C C   . ALA   C 3 35  ? 97.289  144.554 87.450  1.00 80.23  ? 35  ALA   D C   1 
ATOM   4315 O O   . ALA   C 3 35  ? 97.089  143.341 87.546  1.00 80.23  ? 35  ALA   D O   1 
ATOM   4316 C CB  . ALA   C 3 35  ? 95.256  145.922 86.943  1.00 80.23  ? 35  ALA   D CB  1 
ATOM   4317 N N   . ASP   C 3 36  ? 98.379  145.053 86.869  1.00 81.14  ? 36  ASP   D N   1 
ATOM   4318 C CA  . ASP   C 3 36  ? 99.441  144.161 86.414  1.00 81.14  ? 36  ASP   D CA  1 
ATOM   4319 C C   . ASP   C 3 36  ? 100.059 143.399 87.580  1.00 81.14  ? 36  ASP   D C   1 
ATOM   4320 O O   . ASP   C 3 36  ? 100.291 142.186 87.487  1.00 81.14  ? 36  ASP   D O   1 
ATOM   4321 C CB  . ASP   C 3 36  ? 100.511 144.955 85.668  1.00 81.14  ? 36  ASP   D CB  1 
ATOM   4322 C CG  . ASP   C 3 36  ? 100.050 145.408 84.296  1.00 81.14  ? 36  ASP   D CG  1 
ATOM   4323 O OD1 . ASP   C 3 36  ? 98.870  145.178 83.957  1.00 81.14  ? 36  ASP   D OD1 1 
ATOM   4324 O OD2 . ASP   C 3 36  ? 100.867 145.996 83.557  1.00 81.14  ? 36  ASP   D OD2 1 
ATOM   4325 N N   . LEU   C 3 37  ? 100.330 144.094 88.690  1.00 74.83  ? 37  LEU   D N   1 
ATOM   4326 C CA  . LEU   C 3 37  ? 100.885 143.414 89.861  1.00 74.83  ? 37  LEU   D CA  1 
ATOM   4327 C C   . LEU   C 3 37  ? 99.903  142.398 90.427  1.00 74.83  ? 37  LEU   D C   1 
ATOM   4328 O O   . LEU   C 3 37  ? 100.291 141.278 90.783  1.00 74.83  ? 37  LEU   D O   1 
ATOM   4329 C CB  . LEU   C 3 37  ? 101.278 144.421 90.940  1.00 74.83  ? 37  LEU   D CB  1 
ATOM   4330 C CG  . LEU   C 3 37  ? 102.460 145.335 90.630  1.00 74.83  ? 37  LEU   D CG  1 
ATOM   4331 C CD1 . LEU   C 3 37  ? 102.919 146.049 91.883  1.00 74.83  ? 37  LEU   D CD1 1 
ATOM   4332 C CD2 . LEU   C 3 37  ? 103.601 144.557 90.008  1.00 74.83  ? 37  LEU   D CD2 1 
ATOM   4333 N N   . MET   C 3 38  ? 98.626  142.773 90.518  1.00 75.22  ? 38  MET   D N   1 
ATOM   4334 C CA  . MET   C 3 38  ? 97.599  141.841 90.968  1.00 75.22  ? 38  MET   D CA  1 
ATOM   4335 C C   . MET   C 3 38  ? 97.550  140.606 90.086  1.00 75.22  ? 38  MET   D C   1 
ATOM   4336 O O   . MET   C 3 38  ? 97.468  139.480 90.587  1.00 75.22  ? 38  MET   D O   1 
ATOM   4337 C CB  . MET   C 3 38  ? 96.238  142.528 90.969  1.00 75.22  ? 38  MET   D CB  1 
ATOM   4338 C CG  . MET   C 3 38  ? 96.068  143.614 91.992  1.00 75.22  ? 38  MET   D CG  1 
ATOM   4339 S SD  . MET   C 3 38  ? 94.477  144.429 91.778  1.00 75.22  ? 38  MET   D SD  1 
ATOM   4340 C CE  . MET   C 3 38  ? 93.342  143.142 92.282  1.00 75.22  ? 38  MET   D CE  1 
ATOM   4341 N N   . ALA   C 3 39  ? 97.584  140.799 88.768  1.00 72.13  ? 39  ALA   D N   1 
ATOM   4342 C CA  . ALA   C 3 39  ? 97.506  139.675 87.848  1.00 72.13  ? 39  ALA   D CA  1 
ATOM   4343 C C   . ALA   C 3 39  ? 98.703  138.752 88.000  1.00 72.13  ? 39  ALA   D C   1 
ATOM   4344 O O   . ALA   C 3 39  ? 98.547  137.526 88.044  1.00 72.13  ? 39  ALA   D O   1 
ATOM   4345 C CB  . ALA   C 3 39  ? 97.401  140.181 86.412  1.00 72.13  ? 39  ALA   D CB  1 
ATOM   4346 N N   . TYR   C 3 40  ? 99.908  139.319 88.089  1.00 67.36  ? 40  TYR   D N   1 
ATOM   4347 C CA  . TYR   C 3 40  ? 101.089 138.473 88.223  1.00 67.36  ? 40  TYR   D CA  1 
ATOM   4348 C C   . TYR   C 3 40  ? 101.087 137.719 89.541  1.00 67.36  ? 40  TYR   D C   1 
ATOM   4349 O O   . TYR   C 3 40  ? 101.485 136.551 89.591  1.00 67.36  ? 40  TYR   D O   1 
ATOM   4350 C CB  . TYR   C 3 40  ? 102.360 139.295 88.089  1.00 67.36  ? 40  TYR   D CB  1 
ATOM   4351 C CG  . TYR   C 3 40  ? 103.583 138.435 87.951  1.00 67.36  ? 40  TYR   D CG  1 
ATOM   4352 C CD1 . TYR   C 3 40  ? 104.318 138.065 89.058  1.00 67.36  ? 40  TYR   D CD1 1 
ATOM   4353 C CD2 . TYR   C 3 40  ? 103.999 137.989 86.711  1.00 67.36  ? 40  TYR   D CD2 1 
ATOM   4354 C CE1 . TYR   C 3 40  ? 105.428 137.280 88.939  1.00 67.36  ? 40  TYR   D CE1 1 
ATOM   4355 C CE2 . TYR   C 3 40  ? 105.115 137.200 86.581  1.00 67.36  ? 40  TYR   D CE2 1 
ATOM   4356 C CZ  . TYR   C 3 40  ? 105.825 136.849 87.702  1.00 67.36  ? 40  TYR   D CZ  1 
ATOM   4357 O OH  . TYR   C 3 40  ? 106.945 136.059 87.583  1.00 67.36  ? 40  TYR   D OH  1 
ATOM   4358 N N   . CYS   C 3 41  ? 100.651 138.360 90.621  1.00 70.62  ? 41  CYS   D N   1 
ATOM   4359 C CA  . CYS   C 3 41  ? 100.593 137.668 91.903  1.00 70.62  ? 41  CYS   D CA  1 
ATOM   4360 C C   . CYS   C 3 41  ? 99.552  136.555 91.892  1.00 70.62  ? 41  CYS   D C   1 
ATOM   4361 O O   . CYS   C 3 41  ? 99.810  135.446 92.372  1.00 70.62  ? 41  CYS   D O   1 
ATOM   4362 C CB  . CYS   C 3 41  ? 100.299 138.663 93.019  1.00 70.62  ? 41  CYS   D CB  1 
ATOM   4363 S SG  . CYS   C 3 41  ? 99.911  137.880 94.589  1.00 70.62  ? 41  CYS   D SG  1 
ATOM   4364 N N   . GLU   C 3 42  ? 98.364  136.834 91.352  1.00 73.36  ? 42  GLU   D N   1 
ATOM   4365 C CA  . GLU   C 3 42  ? 97.271  135.872 91.428  1.00 73.36  ? 42  GLU   D CA  1 
ATOM   4366 C C   . GLU   C 3 42  ? 97.500  134.694 90.491  1.00 73.36  ? 42  GLU   D C   1 
ATOM   4367 O O   . GLU   C 3 42  ? 97.156  133.554 90.824  1.00 73.36  ? 42  GLU   D O   1 
ATOM   4368 C CB  . GLU   C 3 42  ? 95.947  136.570 91.119  1.00 73.36  ? 42  GLU   D CB  1 
ATOM   4369 C CG  . GLU   C 3 42  ? 94.860  135.665 90.580  1.00 73.36  ? 42  GLU   D CG  1 
ATOM   4370 C CD  . GLU   C 3 42  ? 93.519  136.364 90.477  1.00 73.36  ? 42  GLU   D CD  1 
ATOM   4371 O OE1 . GLU   C 3 42  ? 93.502  137.605 90.336  1.00 73.36  ? 42  GLU   D OE1 1 
ATOM   4372 O OE2 . GLU   C 3 42  ? 92.480  135.673 90.537  1.00 73.36  ? 42  GLU   D OE2 1 
ATOM   4373 N N   . ALA   C 3 43  ? 98.094  134.941 89.324  1.00 71.51  ? 43  ALA   D N   1 
ATOM   4374 C CA  . ALA   C 3 43  ? 98.291  133.876 88.350  1.00 71.51  ? 43  ALA   D CA  1 
ATOM   4375 C C   . ALA   C 3 43  ? 99.345  132.864 88.775  1.00 71.51  ? 43  ALA   D C   1 
ATOM   4376 O O   . ALA   C 3 43  ? 99.471  131.823 88.123  1.00 71.51  ? 43  ALA   D O   1 
ATOM   4377 C CB  . ALA   C 3 43  ? 98.665  134.472 86.994  1.00 71.51  ? 43  ALA   D CB  1 
ATOM   4378 N N   . HIS   C 3 44  ? 100.101 133.135 89.837  1.00 71.22  ? 44  HIS   D N   1 
ATOM   4379 C CA  . HIS   C 3 44  ? 101.135 132.223 90.307  1.00 71.22  ? 44  HIS   D CA  1 
ATOM   4380 C C   . HIS   C 3 44  ? 100.904 131.756 91.734  1.00 71.22  ? 44  HIS   D C   1 
ATOM   4381 O O   . HIS   C 3 44  ? 101.785 131.114 92.315  1.00 71.22  ? 44  HIS   D O   1 
ATOM   4382 C CB  . HIS   C 3 44  ? 102.509 132.880 90.201  1.00 71.22  ? 44  HIS   D CB  1 
ATOM   4383 C CG  . HIS   C 3 44  ? 103.008 133.008 88.801  1.00 71.22  ? 44  HIS   D CG  1 
ATOM   4384 N ND1 . HIS   C 3 44  ? 102.468 133.896 87.899  1.00 71.22  ? 44  HIS   D ND1 1 
ATOM   4385 C CD2 . HIS   C 3 44  ? 104.009 132.373 88.151  1.00 71.22  ? 44  HIS   D CD2 1 
ATOM   4386 C CE1 . HIS   C 3 44  ? 103.110 133.797 86.750  1.00 71.22  ? 44  HIS   D CE1 1 
ATOM   4387 N NE2 . HIS   C 3 44  ? 104.051 132.880 86.877  1.00 71.22  ? 44  HIS   D NE2 1 
ATOM   4388 N N   . ALA   C 3 45  ? 99.746  132.055 92.317  1.00 74.24  ? 45  ALA   D N   1 
ATOM   4389 C CA  . ALA   C 3 45  ? 99.449  131.599 93.666  1.00 74.24  ? 45  ALA   D CA  1 
ATOM   4390 C C   . ALA   C 3 45  ? 99.288  130.091 93.747  1.00 74.24  ? 45  ALA   D C   1 
ATOM   4391 O O   . ALA   C 3 45  ? 99.222  129.553 94.856  1.00 74.24  ? 45  ALA   D O   1 
ATOM   4392 C CB  . ALA   C 3 45  ? 98.185  132.282 94.188  1.00 74.24  ? 45  ALA   D CB  1 
ATOM   4393 N N   . LYS   C 3 46  ? 99.202  129.405 92.614  1.00 78.78  ? 46  LYS   D N   1 
ATOM   4394 C CA  . LYS   C 3 46  ? 99.174  127.951 92.587  1.00 78.78  ? 46  LYS   D CA  1 
ATOM   4395 C C   . LYS   C 3 46  ? 100.555 127.338 92.400  1.00 78.78  ? 46  LYS   D C   1 
ATOM   4396 O O   . LYS   C 3 46  ? 100.667 126.110 92.345  1.00 78.78  ? 46  LYS   D O   1 
ATOM   4397 C CB  . LYS   C 3 46  ? 98.241  127.460 91.475  1.00 78.78  ? 46  LYS   D CB  1 
ATOM   4398 N N   . GLU   C 3 47  ? 101.602 128.152 92.301  1.00 79.34  ? 47  GLU   D N   1 
ATOM   4399 C CA  . GLU   C 3 47  ? 102.957 127.652 92.090  1.00 79.34  ? 47  GLU   D CA  1 
ATOM   4400 C C   . GLU   C 3 47  ? 103.953 128.404 92.960  1.00 79.34  ? 47  GLU   D C   1 
ATOM   4401 O O   . GLU   C 3 47  ? 105.022 128.811 92.495  1.00 79.34  ? 47  GLU   D O   1 
ATOM   4402 C CB  . GLU   C 3 47  ? 103.360 127.746 90.620  1.00 79.34  ? 47  GLU   D CB  1 
ATOM   4403 C CG  . GLU   C 3 47  ? 102.617 126.786 89.705  1.00 79.34  ? 47  GLU   D CG  1 
ATOM   4404 C CD  . GLU   C 3 47  ? 102.685 127.199 88.248  1.00 79.34  ? 47  GLU   D CD  1 
ATOM   4405 O OE1 . GLU   C 3 47  ? 103.796 127.509 87.767  1.00 79.34  ? 47  GLU   D OE1 1 
ATOM   4406 O OE2 . GLU   C 3 47  ? 101.628 127.214 87.583  1.00 79.34  ? 47  GLU   D OE2 1 
ATOM   4407 N N   . ASP   C 3 48  ? 103.621 128.603 94.235  1.00 76.41  ? 48  ASP   D N   1 
ATOM   4408 C CA  . ASP   C 3 48  ? 104.523 129.248 95.179  1.00 76.41  ? 48  ASP   D CA  1 
ATOM   4409 C C   . ASP   C 3 48  ? 104.527 128.446 96.475  1.00 76.41  ? 48  ASP   D C   1 
ATOM   4410 O O   . ASP   C 3 48  ? 103.454 128.184 97.045  1.00 76.41  ? 48  ASP   D O   1 
ATOM   4411 C CB  . ASP   C 3 48  ? 104.107 130.694 95.443  1.00 76.41  ? 48  ASP   D CB  1 
ATOM   4412 C CG  . ASP   C 3 48  ? 102.614 130.843 95.631  1.00 76.41  ? 48  ASP   D CG  1 
ATOM   4413 O OD1 . ASP   C 3 48  ? 101.887 129.864 95.370  1.00 76.41  ? 48  ASP   D OD1 1 
ATOM   4414 O OD2 . ASP   C 3 48  ? 102.166 131.937 96.032  1.00 76.41  ? 48  ASP   D OD2 1 
ATOM   4415 N N   . PRO   C 3 49  ? 105.696 128.038 96.972  1.00 73.75  ? 49  PRO   D N   1 
ATOM   4416 C CA  . PRO   C 3 49  ? 105.735 127.081 98.086  1.00 73.75  ? 49  PRO   D CA  1 
ATOM   4417 C C   . PRO   C 3 49  ? 105.560 127.686 99.466  1.00 73.75  ? 49  PRO   D C   1 
ATOM   4418 O O   . PRO   C 3 49  ? 105.389 126.924 100.427 1.00 73.75  ? 49  PRO   D O   1 
ATOM   4419 C CB  . PRO   C 3 49  ? 107.130 126.448 97.951  1.00 73.75  ? 49  PRO   D CB  1 
ATOM   4420 C CG  . PRO   C 3 49  ? 107.620 126.840 96.585  1.00 73.75  ? 49  PRO   D CG  1 
ATOM   4421 C CD  . PRO   C 3 49  ? 107.004 128.170 96.321  1.00 73.75  ? 49  PRO   D CD  1 
ATOM   4422 N N   . LEU   C 3 50  ? 105.600 129.007 99.613  1.00 72.76  ? 50  LEU   D N   1 
ATOM   4423 C CA  . LEU   C 3 50  ? 105.499 129.621 100.930 1.00 72.76  ? 50  LEU   D CA  1 
ATOM   4424 C C   . LEU   C 3 50  ? 104.128 130.206 101.220 1.00 72.76  ? 50  LEU   D C   1 
ATOM   4425 O O   . LEU   C 3 50  ? 103.719 130.240 102.384 1.00 72.76  ? 50  LEU   D O   1 
ATOM   4426 C CB  . LEU   C 3 50  ? 106.553 130.721 101.086 1.00 72.76  ? 50  LEU   D CB  1 
ATOM   4427 C CG  . LEU   C 3 50  ? 108.003 130.271 101.251 1.00 72.76  ? 50  LEU   D CG  1 
ATOM   4428 C CD1 . LEU   C 3 50  ? 108.940 131.452 101.200 1.00 72.76  ? 50  LEU   D CD1 1 
ATOM   4429 C CD2 . LEU   C 3 50  ? 108.178 129.519 102.552 1.00 72.76  ? 50  LEU   D CD2 1 
ATOM   4430 N N   . LEU   C 3 51  ? 103.410 130.672 100.200 1.00 77.86  ? 51  LEU   D N   1 
ATOM   4431 C CA  . LEU   C 3 51  ? 102.095 131.258 100.432 1.00 77.86  ? 51  LEU   D CA  1 
ATOM   4432 C C   . LEU   C 3 51  ? 101.102 130.213 100.918 1.00 77.86  ? 51  LEU   D C   1 
ATOM   4433 O O   . LEU   C 3 51  ? 100.317 130.473 101.836 1.00 77.86  ? 51  LEU   D O   1 
ATOM   4434 C CB  . LEU   C 3 51  ? 101.588 131.930 99.160  1.00 77.86  ? 51  LEU   D CB  1 
ATOM   4435 C CG  . LEU   C 3 51  ? 100.445 132.921 99.341  1.00 77.86  ? 51  LEU   D CG  1 
ATOM   4436 C CD1 . LEU   C 3 51  ? 100.943 134.163 100.057 1.00 77.86  ? 51  LEU   D CD1 1 
ATOM   4437 C CD2 . LEU   C 3 51  ? 99.831  133.281 98.000  1.00 77.86  ? 51  LEU   D CD2 1 
ATOM   4438 N N   . THR   C 3 52  ? 101.116 129.037 100.317 1.00 86.67  ? 52  THR   D N   1 
ATOM   4439 C CA  . THR   C 3 52  ? 100.320 127.908 100.759 1.00 86.67  ? 52  THR   D CA  1 
ATOM   4440 C C   . THR   C 3 52  ? 101.233 126.832 101.337 1.00 86.67  ? 52  THR   D C   1 
ATOM   4441 O O   . THR   C 3 52  ? 102.385 126.703 100.911 1.00 86.67  ? 52  THR   D O   1 
ATOM   4442 C CB  . THR   C 3 52  ? 99.503  127.312 99.607  1.00 86.67  ? 52  THR   D CB  1 
ATOM   4443 O OG1 . THR   C 3 52  ? 100.389 126.838 98.585  1.00 86.67  ? 52  THR   D OG1 1 
ATOM   4444 C CG2 . THR   C 3 52  ? 98.571  128.360 99.017  1.00 86.67  ? 52  THR   D CG2 1 
ATOM   4445 N N   . PRO   C 3 53  ? 100.766 126.065 102.322 1.00 91.51  ? 53  PRO   D N   1 
ATOM   4446 C CA  . PRO   C 3 53  ? 101.636 125.061 102.946 1.00 91.51  ? 53  PRO   D CA  1 
ATOM   4447 C C   . PRO   C 3 53  ? 102.176 124.084 101.915 1.00 91.51  ? 53  PRO   D C   1 
ATOM   4448 O O   . PRO   C 3 53  ? 101.433 123.552 101.088 1.00 91.51  ? 53  PRO   D O   1 
ATOM   4449 C CB  . PRO   C 3 53  ? 100.713 124.370 103.956 1.00 91.51  ? 53  PRO   D CB  1 
ATOM   4450 C CG  . PRO   C 3 53  ? 99.653  125.377 104.248 1.00 91.51  ? 53  PRO   D CG  1 
ATOM   4451 C CD  . PRO   C 3 53  ? 99.444  126.132 102.969 1.00 91.51  ? 53  PRO   D CD  1 
ATOM   4452 N N   . VAL   C 3 54  ? 103.485 123.857 101.967 1.00 91.91  ? 54  VAL   D N   1 
ATOM   4453 C CA  . VAL   C 3 54  ? 104.166 123.013 100.990 1.00 91.91  ? 54  VAL   D CA  1 
ATOM   4454 C C   . VAL   C 3 54  ? 103.894 121.548 101.305 1.00 91.91  ? 54  VAL   D C   1 
ATOM   4455 O O   . VAL   C 3 54  ? 103.840 121.167 102.483 1.00 91.91  ? 54  VAL   D O   1 
ATOM   4456 C CB  . VAL   C 3 54  ? 105.676 123.299 100.965 1.00 91.91  ? 54  VAL   D CB  1 
ATOM   4457 N N   . PRO   C 3 55  ? 103.707 120.699 100.299 1.00 93.47  ? 55  PRO   D N   1 
ATOM   4458 C CA  . PRO   C 3 55  ? 103.532 119.269 100.570 1.00 93.47  ? 55  PRO   D CA  1 
ATOM   4459 C C   . PRO   C 3 55  ? 104.826 118.644 101.065 1.00 93.47  ? 55  PRO   D C   1 
ATOM   4460 O O   . PRO   C 3 55  ? 105.927 119.088 100.732 1.00 93.47  ? 55  PRO   D O   1 
ATOM   4461 C CB  . PRO   C 3 55  ? 103.119 118.697 99.210  1.00 93.47  ? 55  PRO   D CB  1 
ATOM   4462 C CG  . PRO   C 3 55  ? 103.667 119.661 98.214  1.00 93.47  ? 55  PRO   D CG  1 
ATOM   4463 C CD  . PRO   C 3 55  ? 103.614 121.013 98.863  1.00 93.47  ? 55  PRO   D CD  1 
ATOM   4464 N N   . ALA   C 3 56  ? 104.680 117.596 101.877 1.00 91.93  ? 56  ALA   D N   1 
ATOM   4465 C CA  . ALA   C 3 56  ? 105.846 116.892 102.398 1.00 91.93  ? 56  ALA   D CA  1 
ATOM   4466 C C   . ALA   C 3 56  ? 106.625 116.160 101.315 1.00 91.93  ? 56  ALA   D C   1 
ATOM   4467 O O   . ALA   C 3 56  ? 107.786 115.808 101.544 1.00 91.93  ? 56  ALA   D O   1 
ATOM   4468 C CB  . ALA   C 3 56  ? 105.423 115.906 103.487 1.00 91.93  ? 56  ALA   D CB  1 
ATOM   4469 N N   . SER   C 3 57  ? 106.020 115.923 100.151 1.00 91.51  ? 57  SER   D N   1 
ATOM   4470 C CA  . SER   C 3 57  ? 106.723 115.243 99.071  1.00 91.51  ? 57  SER   D CA  1 
ATOM   4471 C C   . SER   C 3 57  ? 107.709 116.158 98.357  1.00 91.51  ? 57  SER   D C   1 
ATOM   4472 O O   . SER   C 3 57  ? 108.778 115.702 97.939  1.00 91.51  ? 57  SER   D O   1 
ATOM   4473 C CB  . SER   C 3 57  ? 105.718 114.675 98.068  1.00 91.51  ? 57  SER   D CB  1 
ATOM   4474 O OG  . SER   C 3 57  ? 105.007 115.714 97.419  1.00 91.51  ? 57  SER   D OG  1 
ATOM   4475 N N   . GLU   C 3 58  ? 107.375 117.439 98.210  1.00 86.11  ? 58  GLU   D N   1 
ATOM   4476 C CA  . GLU   C 3 58  ? 108.201 118.387 97.477  1.00 86.11  ? 58  GLU   D CA  1 
ATOM   4477 C C   . GLU   C 3 58  ? 109.050 119.263 98.389  1.00 86.11  ? 58  GLU   D C   1 
ATOM   4478 O O   . GLU   C 3 58  ? 109.641 120.239 97.917  1.00 86.11  ? 58  GLU   D O   1 
ATOM   4479 C CB  . GLU   C 3 58  ? 107.325 119.264 96.580  1.00 86.11  ? 58  GLU   D CB  1 
ATOM   4480 N N   . ASN   C 3 59  ? 109.127 118.939 99.678  1.00 76.56  ? 59  ASN   D N   1 
ATOM   4481 C CA  . ASN   C 3 59  ? 109.902 119.729 100.620 1.00 76.56  ? 59  ASN   D CA  1 
ATOM   4482 C C   . ASN   C 3 59  ? 111.208 119.012 100.916 1.00 76.56  ? 59  ASN   D C   1 
ATOM   4483 O O   . ASN   C 3 59  ? 111.195 117.990 101.619 1.00 76.56  ? 59  ASN   D O   1 
ATOM   4484 C CB  . ASN   C 3 59  ? 109.113 119.950 101.908 1.00 76.56  ? 59  ASN   D CB  1 
ATOM   4485 C CG  . ASN   C 3 59  ? 109.866 120.792 102.920 1.00 76.56  ? 59  ASN   D CG  1 
ATOM   4486 O OD1 . ASN   C 3 59  ? 110.844 121.462 102.587 1.00 76.56  ? 59  ASN   D OD1 1 
ATOM   4487 N ND2 . ASN   C 3 59  ? 109.416 120.754 104.168 1.00 76.56  ? 59  ASN   D ND2 1 
ATOM   4488 N N   . PRO   C 3 60  ? 112.348 119.492 100.414 1.00 69.35  ? 60  PRO   D N   1 
ATOM   4489 C CA  . PRO   C 3 60  ? 113.619 118.838 100.743 1.00 69.35  ? 60  PRO   D CA  1 
ATOM   4490 C C   . PRO   C 3 60  ? 114.101 119.140 102.145 1.00 69.35  ? 60  PRO   D C   1 
ATOM   4491 O O   . PRO   C 3 60  ? 114.983 118.431 102.644 1.00 69.35  ? 60  PRO   D O   1 
ATOM   4492 C CB  . PRO   C 3 60  ? 114.589 119.393 99.691  1.00 69.35  ? 60  PRO   D CB  1 
ATOM   4493 C CG  . PRO   C 3 60  ? 113.727 120.093 98.674  1.00 69.35  ? 60  PRO   D CG  1 
ATOM   4494 C CD  . PRO   C 3 60  ? 112.524 120.556 99.417  1.00 69.35  ? 60  PRO   D CD  1 
ATOM   4495 N N   . PHE   C 3 61  ? 113.560 120.164 102.794 1.00 64.16  ? 61  PHE   D N   1 
ATOM   4496 C CA  . PHE   C 3 61  ? 113.971 120.515 104.143 1.00 64.16  ? 61  PHE   D CA  1 
ATOM   4497 C C   . PHE   C 3 61  ? 113.010 119.927 105.168 1.00 64.16  ? 61  PHE   D C   1 
ATOM   4498 O O   . PHE   C 3 61  ? 112.721 118.731 105.155 1.00 64.16  ? 61  PHE   D O   1 
ATOM   4499 C CB  . PHE   C 3 61  ? 114.050 122.032 104.315 1.00 64.16  ? 61  PHE   D CB  1 
ATOM   4500 C CG  . PHE   C 3 61  ? 114.782 122.740 103.213 1.00 64.16  ? 61  PHE   D CG  1 
ATOM   4501 C CD1 . PHE   C 3 61  ? 114.103 123.243 102.123 1.00 64.16  ? 61  PHE   D CD1 1 
ATOM   4502 C CD2 . PHE   C 3 61  ? 116.144 122.931 103.282 1.00 64.16  ? 61  PHE   D CD2 1 
ATOM   4503 C CE1 . PHE   C 3 61  ? 114.779 123.905 101.115 1.00 64.16  ? 61  PHE   D CE1 1 
ATOM   4504 C CE2 . PHE   C 3 61  ? 116.816 123.590 102.280 1.00 64.16  ? 61  PHE   D CE2 1 
ATOM   4505 C CZ  . PHE   C 3 61  ? 116.135 124.080 101.200 1.00 64.16  ? 61  PHE   D CZ  1 
ATOM   4506 N N   . VAL   D 4 2   ? 148.827 118.326 86.599  1.00 67.89  ? 2   VAL   E N   1 
ATOM   4507 C CA  . VAL   D 4 2   ? 148.732 117.304 87.631  1.00 67.89  ? 2   VAL   E CA  1 
ATOM   4508 C C   . VAL   D 4 2   ? 149.425 116.033 87.171  1.00 67.89  ? 2   VAL   E C   1 
ATOM   4509 O O   . VAL   D 4 2   ? 149.325 115.651 86.006  1.00 67.89  ? 2   VAL   E O   1 
ATOM   4510 C CB  . VAL   D 4 2   ? 147.269 117.040 88.010  1.00 67.89  ? 2   VAL   E CB  1 
ATOM   4511 C CG1 . VAL   D 4 2   ? 146.696 118.240 88.735  1.00 67.89  ? 2   VAL   E CG1 1 
ATOM   4512 C CG2 . VAL   D 4 2   ? 146.448 116.758 86.770  1.00 67.89  ? 2   VAL   E CG2 1 
ATOM   4513 N N   . GLN   D 4 3   ? 150.139 115.379 88.085  1.00 66.23  ? 3   GLN   E N   1 
ATOM   4514 C CA  . GLN   D 4 3   ? 150.939 114.216 87.720  1.00 66.23  ? 3   GLN   E CA  1 
ATOM   4515 C C   . GLN   D 4 3   ? 151.074 113.288 88.917  1.00 66.23  ? 3   GLN   E C   1 
ATOM   4516 O O   . GLN   D 4 3   ? 151.680 113.662 89.924  1.00 66.23  ? 3   GLN   E O   1 
ATOM   4517 C CB  . GLN   D 4 3   ? 152.315 114.648 87.217  1.00 66.23  ? 3   GLN   E CB  1 
ATOM   4518 C CG  . GLN   D 4 3   ? 153.110 113.548 86.554  1.00 66.23  ? 3   GLN   E CG  1 
ATOM   4519 C CD  . GLN   D 4 3   ? 152.442 113.031 85.298  1.00 66.23  ? 3   GLN   E CD  1 
ATOM   4520 O OE1 . GLN   D 4 3   ? 151.858 111.947 85.292  1.00 66.23  ? 3   GLN   E OE1 1 
ATOM   4521 N NE2 . GLN   D 4 3   ? 152.524 113.806 84.223  1.00 66.23  ? 3   GLN   E NE2 1 
ATOM   4522 N N   . LEU   D 4 4   ? 150.511 112.087 88.805  1.00 64.22  ? 4   LEU   E N   1 
ATOM   4523 C CA  . LEU   D 4 4   ? 150.725 111.005 89.760  1.00 64.22  ? 4   LEU   E CA  1 
ATOM   4524 C C   . LEU   D 4 4   ? 151.691 110.008 89.141  1.00 64.22  ? 4   LEU   E C   1 
ATOM   4525 O O   . LEU   D 4 4   ? 151.368 109.374 88.132  1.00 64.22  ? 4   LEU   E O   1 
ATOM   4526 C CB  . LEU   D 4 4   ? 149.414 110.310 90.119  1.00 64.22  ? 4   LEU   E CB  1 
ATOM   4527 C CG  . LEU   D 4 4   ? 148.731 110.695 91.422  1.00 64.22  ? 4   LEU   E CG  1 
ATOM   4528 C CD1 . LEU   D 4 4   ? 148.573 112.178 91.467  1.00 64.22  ? 4   LEU   E CD1 1 
ATOM   4529 C CD2 . LEU   D 4 4   ? 147.389 110.020 91.516  1.00 64.22  ? 4   LEU   E CD2 1 
ATOM   4530 N N   . VAL   D 4 5   ? 152.867 109.869 89.740  1.00 66.65  ? 5   VAL   E N   1 
ATOM   4531 C CA  . VAL   D 4 5   ? 153.905 108.977 89.241  1.00 66.65  ? 5   VAL   E CA  1 
ATOM   4532 C C   . VAL   D 4 5   ? 154.156 107.907 90.289  1.00 66.65  ? 5   VAL   E C   1 
ATOM   4533 O O   . VAL   D 4 5   ? 154.450 108.224 91.446  1.00 66.65  ? 5   VAL   E O   1 
ATOM   4534 C CB  . VAL   D 4 5   ? 155.202 109.736 88.917  1.00 66.65  ? 5   VAL   E CB  1 
ATOM   4535 C CG1 . VAL   D 4 5   ? 156.314 108.759 88.594  1.00 66.65  ? 5   VAL   E CG1 1 
ATOM   4536 C CG2 . VAL   D 4 5   ? 154.979 110.689 87.760  1.00 66.65  ? 5   VAL   E CG2 1 
ATOM   4537 N N   . GLU   D 4 6   ? 154.044 106.646 89.885  1.00 68.97  ? 6   GLU   E N   1 
ATOM   4538 C CA  . GLU   D 4 6   ? 154.191 105.518 90.792  1.00 68.97  ? 6   GLU   E CA  1 
ATOM   4539 C C   . GLU   D 4 6   ? 155.512 104.813 90.529  1.00 68.97  ? 6   GLU   E C   1 
ATOM   4540 O O   . GLU   D 4 6   ? 155.837 104.502 89.379  1.00 68.97  ? 6   GLU   E O   1 
ATOM   4541 C CB  . GLU   D 4 6   ? 153.034 104.530 90.640  1.00 68.97  ? 6   GLU   E CB  1 
ATOM   4542 C CG  . GLU   D 4 6   ? 151.663 105.114 90.884  1.00 68.97  ? 6   GLU   E CG  1 
ATOM   4543 C CD  . GLU   D 4 6   ? 151.022 105.621 89.613  1.00 68.97  ? 6   GLU   E CD  1 
ATOM   4544 O OE1 . GLU   D 4 6   ? 151.751 105.849 88.625  1.00 68.97  ? 6   GLU   E OE1 1 
ATOM   4545 O OE2 . GLU   D 4 6   ? 149.786 105.780 89.594  1.00 68.97  ? 6   GLU   E OE2 1 
ATOM   4546 N N   . SER   D 4 7   ? 156.265 104.567 91.594  1.00 70.40  ? 7   SER   E N   1 
ATOM   4547 C CA  . SER   D 4 7   ? 157.520 103.840 91.521  1.00 70.40  ? 7   SER   E CA  1 
ATOM   4548 C C   . SER   D 4 7   ? 157.466 102.679 92.498  1.00 70.40  ? 7   SER   E C   1 
ATOM   4549 O O   . SER   D 4 7   ? 156.759 102.729 93.506  1.00 70.40  ? 7   SER   E O   1 
ATOM   4550 C CB  . SER   D 4 7   ? 158.721 104.742 91.836  1.00 70.40  ? 7   SER   E CB  1 
ATOM   4551 O OG  . SER   D 4 7   ? 158.663 105.946 91.091  1.00 70.40  ? 7   SER   E OG  1 
ATOM   4552 N N   . GLY   D 4 8   ? 158.218 101.636 92.195  1.00 71.92  ? 8   GLY   E N   1 
ATOM   4553 C CA  . GLY   D 4 8   ? 158.160 100.401 92.945  1.00 71.92  ? 8   GLY   E CA  1 
ATOM   4554 C C   . GLY   D 4 8   ? 157.549 99.278  92.127  1.00 71.92  ? 8   GLY   E C   1 
ATOM   4555 O O   . GLY   D 4 8   ? 156.981 99.478  91.054  1.00 71.92  ? 8   GLY   E O   1 
ATOM   4556 N N   . GLY   D 4 9   ? 157.696 98.070  92.652  1.00 73.87  ? 9   GLY   E N   1 
ATOM   4557 C CA  . GLY   D 4 9   ? 157.191 96.910  91.954  1.00 73.87  ? 9   GLY   E CA  1 
ATOM   4558 C C   . GLY   D 4 9   ? 158.134 96.414  90.881  1.00 73.87  ? 9   GLY   E C   1 
ATOM   4559 O O   . GLY   D 4 9   ? 158.627 97.195  90.063  1.00 73.87  ? 9   GLY   E O   1 
ATOM   4560 N N   . GLY   D 4 10  ? 158.378 95.109  90.875  1.00 77.08  ? 10  GLY   E N   1 
ATOM   4561 C CA  . GLY   D 4 10  ? 159.280 94.479  89.936  1.00 77.08  ? 10  GLY   E CA  1 
ATOM   4562 C C   . GLY   D 4 10  ? 159.069 92.981  89.925  1.00 77.08  ? 10  GLY   E C   1 
ATOM   4563 O O   . GLY   D 4 10  ? 157.925 92.516  89.916  1.00 77.08  ? 10  GLY   E O   1 
ATOM   4564 N N   . LEU   D 4 11  ? 160.152 92.212  89.923  1.00 78.29  ? 11  LEU   E N   1 
ATOM   4565 C CA  . LEU   D 4 11  ? 160.076 90.758  89.961  1.00 78.29  ? 11  LEU   E CA  1 
ATOM   4566 C C   . LEU   D 4 11  ? 160.292 90.298  91.396  1.00 78.29  ? 11  LEU   E C   1 
ATOM   4567 O O   . LEU   D 4 11  ? 161.363 90.526  91.969  1.00 78.29  ? 11  LEU   E O   1 
ATOM   4568 C CB  . LEU   D 4 11  ? 161.112 90.137  89.027  1.00 78.29  ? 11  LEU   E CB  1 
ATOM   4569 C CG  . LEU   D 4 11  ? 161.194 88.614  89.028  1.00 78.29  ? 11  LEU   E CG  1 
ATOM   4570 C CD1 . LEU   D 4 11  ? 159.848 88.010  88.688  1.00 78.29  ? 11  LEU   E CD1 1 
ATOM   4571 C CD2 . LEU   D 4 11  ? 162.257 88.141  88.051  1.00 78.29  ? 11  LEU   E CD2 1 
ATOM   4572 N N   . VAL   D 4 12  ? 159.280 89.658  91.974  1.00 77.76  ? 12  VAL   E N   1 
ATOM   4573 C CA  . VAL   D 4 12  ? 159.280 89.297  93.385  1.00 77.76  ? 12  VAL   E CA  1 
ATOM   4574 C C   . VAL   D 4 12  ? 158.908 87.829  93.534  1.00 77.76  ? 12  VAL   E C   1 
ATOM   4575 O O   . VAL   D 4 12  ? 157.989 87.340  92.869  1.00 77.76  ? 12  VAL   E O   1 
ATOM   4576 C CB  . VAL   D 4 12  ? 158.311 90.180  94.194  1.00 77.76  ? 12  VAL   E CB  1 
ATOM   4577 C CG1 . VAL   D 4 12  ? 158.400 89.853  95.668  1.00 77.76  ? 12  VAL   E CG1 1 
ATOM   4578 C CG2 . VAL   D 4 12  ? 158.599 91.643  93.948  1.00 77.76  ? 12  VAL   E CG2 1 
ATOM   4579 N N   . GLN   D 4 13  ? 159.627 87.129  94.407  1.00 79.86  ? 13  GLN   E N   1 
ATOM   4580 C CA  . GLN   D 4 13  ? 159.314 85.750  94.729  1.00 79.86  ? 13  GLN   E CA  1 
ATOM   4581 C C   . GLN   D 4 13  ? 158.028 85.674  95.549  1.00 79.86  ? 13  GLN   E C   1 
ATOM   4582 O O   . GLN   D 4 13  ? 157.653 86.637  96.221  1.00 79.86  ? 13  GLN   E O   1 
ATOM   4583 C CB  . GLN   D 4 13  ? 160.465 85.117  95.506  1.00 79.86  ? 13  GLN   E CB  1 
ATOM   4584 C CG  . GLN   D 4 13  ? 161.734 84.925  94.700  1.00 79.86  ? 13  GLN   E CG  1 
ATOM   4585 C CD  . GLN   D 4 13  ? 161.507 84.122  93.436  1.00 79.86  ? 13  GLN   E CD  1 
ATOM   4586 O OE1 . GLN   D 4 13  ? 161.621 84.643  92.326  1.00 79.86  ? 13  GLN   E OE1 1 
ATOM   4587 N NE2 . GLN   D 4 13  ? 161.184 82.844  93.597  1.00 79.86  ? 13  GLN   E NE2 1 
ATOM   4588 N N   . PRO   D 4 14  ? 157.330 84.540  95.505  1.00 78.37  ? 14  PRO   E N   1 
ATOM   4589 C CA  . PRO   D 4 14  ? 156.079 84.423  96.260  1.00 78.37  ? 14  PRO   E CA  1 
ATOM   4590 C C   . PRO   D 4 14  ? 156.315 84.509  97.759  1.00 78.37  ? 14  PRO   E C   1 
ATOM   4591 O O   . PRO   D 4 14  ? 157.381 84.156  98.267  1.00 78.37  ? 14  PRO   E O   1 
ATOM   4592 C CB  . PRO   D 4 14  ? 155.545 83.045  95.856  1.00 78.37  ? 14  PRO   E CB  1 
ATOM   4593 C CG  . PRO   D 4 14  ? 156.198 82.756  94.554  1.00 78.37  ? 14  PRO   E CG  1 
ATOM   4594 C CD  . PRO   D 4 14  ? 157.560 83.367  94.649  1.00 78.37  ? 14  PRO   E CD  1 
ATOM   4595 N N   . GLY   D 4 15  ? 155.303 85.007  98.464  1.00 76.06  ? 15  GLY   E N   1 
ATOM   4596 C CA  . GLY   D 4 15  ? 155.366 85.161  99.898  1.00 76.06  ? 15  GLY   E CA  1 
ATOM   4597 C C   . GLY   D 4 15  ? 156.175 86.341  100.385 1.00 76.06  ? 15  GLY   E C   1 
ATOM   4598 O O   . GLY   D 4 15  ? 156.334 86.499  101.602 1.00 76.06  ? 15  GLY   E O   1 
ATOM   4599 N N   . GLY   D 4 16  ? 156.687 87.176  99.485  1.00 77.20  ? 16  GLY   E N   1 
ATOM   4600 C CA  . GLY   D 4 16  ? 157.551 88.274  99.856  1.00 77.20  ? 16  GLY   E CA  1 
ATOM   4601 C C   . GLY   D 4 16  ? 156.785 89.530  100.218 1.00 77.20  ? 16  GLY   E C   1 
ATOM   4602 O O   . GLY   D 4 16  ? 155.576 89.519  100.457 1.00 77.20  ? 16  GLY   E O   1 
ATOM   4603 N N   . SER   D 4 17  ? 157.520 90.637  100.261 1.00 73.37  ? 17  SER   E N   1 
ATOM   4604 C CA  . SER   D 4 17  ? 156.964 91.933  100.613 1.00 73.37  ? 17  SER   E CA  1 
ATOM   4605 C C   . SER   D 4 17  ? 157.596 93.001  99.739  1.00 73.37  ? 17  SER   E C   1 
ATOM   4606 O O   . SER   D 4 17  ? 158.768 92.903  99.365  1.00 73.37  ? 17  SER   E O   1 
ATOM   4607 C CB  . SER   D 4 17  ? 157.204 92.262  102.088 1.00 73.37  ? 17  SER   E CB  1 
ATOM   4608 O OG  . SER   D 4 17  ? 156.665 91.256  102.924 1.00 73.37  ? 17  SER   E OG  1 
ATOM   4609 N N   . ARG   D 4 18  ? 156.813 94.028  99.419  1.00 70.29  ? 18  ARG   E N   1 
ATOM   4610 C CA  . ARG   D 4 18  ? 157.300 95.161  98.648  1.00 70.29  ? 18  ARG   E CA  1 
ATOM   4611 C C   . ARG   D 4 18  ? 156.640 96.425  99.164  1.00 70.29  ? 18  ARG   E C   1 
ATOM   4612 O O   . ARG   D 4 18  ? 155.817 96.395  100.082 1.00 70.29  ? 18  ARG   E O   1 
ATOM   4613 C CB  . ARG   D 4 18  ? 157.026 94.998  97.154  1.00 70.29  ? 18  ARG   E CB  1 
ATOM   4614 C CG  . ARG   D 4 18  ? 157.867 93.956  96.492  1.00 70.29  ? 18  ARG   E CG  1 
ATOM   4615 C CD  . ARG   D 4 18  ? 159.253 94.473  96.231  1.00 70.29  ? 18  ARG   E CD  1 
ATOM   4616 N NE  . ARG   D 4 18  ? 159.325 95.224  94.989  1.00 70.29  ? 18  ARG   E NE  1 
ATOM   4617 C CZ  . ARG   D 4 18  ? 160.334 95.137  94.132  1.00 70.29  ? 18  ARG   E CZ  1 
ATOM   4618 N NH1 . ARG   D 4 18  ? 161.354 94.332  94.389  1.00 70.29  ? 18  ARG   E NH1 1 
ATOM   4619 N NH2 . ARG   D 4 18  ? 160.329 95.857  93.020  1.00 70.29  ? 18  ARG   E NH2 1 
ATOM   4620 N N   . LYS   D 4 19  ? 157.008 97.547  98.560  1.00 67.75  ? 19  LYS   E N   1 
ATOM   4621 C CA  . LYS   D 4 19  ? 156.416 98.830  98.892  1.00 67.75  ? 19  LYS   E CA  1 
ATOM   4622 C C   . LYS   D 4 19  ? 156.107 99.567  97.603  1.00 67.75  ? 19  LYS   E C   1 
ATOM   4623 O O   . LYS   D 4 19  ? 156.974 99.686  96.733  1.00 67.75  ? 19  LYS   E O   1 
ATOM   4624 C CB  . LYS   D 4 19  ? 157.351 99.662  99.770  1.00 67.75  ? 19  LYS   E CB  1 
ATOM   4625 C CG  . LYS   D 4 19  ? 156.640 100.454 100.838 1.00 67.75  ? 19  LYS   E CG  1 
ATOM   4626 C CD  . LYS   D 4 19  ? 157.482 101.622 101.288 1.00 67.75  ? 19  LYS   E CD  1 
ATOM   4627 C CE  . LYS   D 4 19  ? 157.074 102.091 102.673 1.00 67.75  ? 19  LYS   E CE  1 
ATOM   4628 N NZ  . LYS   D 4 19  ? 158.014 103.112 103.213 1.00 67.75  ? 19  LYS   E NZ  1 
ATOM   4629 N N   . LEU   D 4 20  ? 154.879 100.059 97.484  1.00 66.08  ? 20  LEU   E N   1 
ATOM   4630 C CA  . LEU   D 4 20  ? 154.444 100.819 96.324  1.00 66.08  ? 20  LEU   E CA  1 
ATOM   4631 C C   . LEU   D 4 20  ? 154.349 102.295 96.681  1.00 66.08  ? 20  LEU   E C   1 
ATOM   4632 O O   . LEU   D 4 20  ? 153.822 102.654 97.738  1.00 66.08  ? 20  LEU   E O   1 
ATOM   4633 C CB  . LEU   D 4 20  ? 153.099 100.312 95.815  1.00 66.08  ? 20  LEU   E CB  1 
ATOM   4634 C CG  . LEU   D 4 20  ? 153.120 98.996  95.040  1.00 66.08  ? 20  LEU   E CG  1 
ATOM   4635 C CD1 . LEU   D 4 20  ? 151.875 98.867  94.187  1.00 66.08  ? 20  LEU   E CD1 1 
ATOM   4636 C CD2 . LEU   D 4 20  ? 154.359 98.898  94.182  1.00 66.08  ? 20  LEU   E CD2 1 
ATOM   4637 N N   . SER   D 4 21  ? 154.865 103.148 95.800  1.00 66.77  ? 21  SER   E N   1 
ATOM   4638 C CA  . SER   D 4 21  ? 154.880 104.586 96.005  1.00 66.77  ? 21  SER   E CA  1 
ATOM   4639 C C   . SER   D 4 21  ? 154.001 105.266 94.964  1.00 66.77  ? 21  SER   E C   1 
ATOM   4640 O O   . SER   D 4 21  ? 153.817 104.755 93.856  1.00 66.77  ? 21  SER   E O   1 
ATOM   4641 C CB  . SER   D 4 21  ? 156.302 105.139 95.920  1.00 66.77  ? 21  SER   E CB  1 
ATOM   4642 O OG  . SER   D 4 21  ? 157.164 104.477 96.828  1.00 66.77  ? 21  SER   E OG  1 
ATOM   4643 N N   . CYS   D 4 22  ? 153.449 106.422 95.334  1.00 66.52  ? 22  CYS   E N   1 
ATOM   4644 C CA  . CYS   D 4 22  ? 152.607 107.226 94.444  1.00 66.52  ? 22  CYS   E CA  1 
ATOM   4645 C C   . CYS   D 4 22  ? 152.947 108.686 94.726  1.00 66.52  ? 22  CYS   E C   1 
ATOM   4646 O O   . CYS   D 4 22  ? 152.353 109.313 95.606  1.00 66.52  ? 22  CYS   E O   1 
ATOM   4647 C CB  . CYS   D 4 22  ? 151.127 106.925 94.662  1.00 66.52  ? 22  CYS   E CB  1 
ATOM   4648 S SG  . CYS   D 4 22  ? 149.948 107.895 93.676  1.00 66.52  ? 22  CYS   E SG  1 
ATOM   4649 N N   . SER   D 4 23  ? 153.907 109.219 93.977  1.00 66.49  ? 23  SER   E N   1 
ATOM   4650 C CA  . SER   D 4 23  ? 154.341 110.596 94.161  1.00 66.49  ? 23  SER   E CA  1 
ATOM   4651 C C   . SER   D 4 23  ? 153.371 111.541 93.471  1.00 66.49  ? 23  SER   E C   1 
ATOM   4652 O O   . SER   D 4 23  ? 152.963 111.302 92.330  1.00 66.49  ? 23  SER   E O   1 
ATOM   4653 C CB  . SER   D 4 23  ? 155.750 110.793 93.611  1.00 66.49  ? 23  SER   E CB  1 
ATOM   4654 O OG  . SER   D 4 23  ? 155.757 110.740 92.197  1.00 66.49  ? 23  SER   E OG  1 
ATOM   4655 N N   . ALA   D 4 24  ? 153.003 112.612 94.160  1.00 64.71  ? 24  ALA   E N   1 
ATOM   4656 C CA  . ALA   D 4 24  ? 152.053 113.580 93.642  1.00 64.71  ? 24  ALA   E CA  1 
ATOM   4657 C C   . ALA   D 4 24  ? 152.752 114.901 93.369  1.00 64.71  ? 24  ALA   E C   1 
ATOM   4658 O O   . ALA   D 4 24  ? 153.734 115.252 94.029  1.00 64.71  ? 24  ALA   E O   1 
ATOM   4659 C CB  . ALA   D 4 24  ? 150.900 113.798 94.618  1.00 64.71  ? 24  ALA   E CB  1 
ATOM   4660 N N   . SER   D 4 25  ? 152.240 115.632 92.386  1.00 67.27  ? 25  SER   E N   1 
ATOM   4661 C CA  . SER   D 4 25  ? 152.822 116.923 92.037  1.00 67.27  ? 25  SER   E CA  1 
ATOM   4662 C C   . SER   D 4 25  ? 151.753 117.761 91.352  1.00 67.27  ? 25  SER   E C   1 
ATOM   4663 O O   . SER   D 4 25  ? 151.394 117.484 90.204  1.00 67.27  ? 25  SER   E O   1 
ATOM   4664 C CB  . SER   D 4 25  ? 154.038 116.743 91.139  1.00 67.27  ? 25  SER   E CB  1 
ATOM   4665 O OG  . SER   D 4 25  ? 153.789 115.781 90.130  1.00 67.27  ? 25  SER   E OG  1 
ATOM   4666 N N   . GLY   D 4 26  ? 151.249 118.772 92.049  1.00 65.03  ? 26  GLY   E N   1 
ATOM   4667 C CA  . GLY   D 4 26  ? 150.395 119.742 91.404  1.00 65.03  ? 26  GLY   E CA  1 
ATOM   4668 C C   . GLY   D 4 26  ? 149.013 119.927 91.988  1.00 65.03  ? 26  GLY   E C   1 
ATOM   4669 O O   . GLY   D 4 26  ? 148.149 120.501 91.318  1.00 65.03  ? 26  GLY   E O   1 
ATOM   4670 N N   . PHE   D 4 27  ? 148.776 119.476 93.218  1.00 62.93  ? 27  PHE   E N   1 
ATOM   4671 C CA  . PHE   D 4 27  ? 147.469 119.686 93.825  1.00 62.93  ? 27  PHE   E CA  1 
ATOM   4672 C C   . PHE   D 4 27  ? 147.552 119.501 95.333  1.00 62.93  ? 27  PHE   E C   1 
ATOM   4673 O O   . PHE   D 4 27  ? 148.563 119.052 95.877  1.00 62.93  ? 27  PHE   E O   1 
ATOM   4674 C CB  . PHE   D 4 27  ? 146.412 118.753 93.222  1.00 62.93  ? 27  PHE   E CB  1 
ATOM   4675 C CG  . PHE   D 4 27  ? 146.759 117.301 93.296  1.00 62.93  ? 27  PHE   E CG  1 
ATOM   4676 C CD1 . PHE   D 4 27  ? 147.533 116.709 92.325  1.00 62.93  ? 27  PHE   E CD1 1 
ATOM   4677 C CD2 . PHE   D 4 27  ? 146.294 116.525 94.335  1.00 62.93  ? 27  PHE   E CD2 1 
ATOM   4678 C CE1 . PHE   D 4 27  ? 147.840 115.385 92.400  1.00 62.93  ? 27  PHE   E CE1 1 
ATOM   4679 C CE2 . PHE   D 4 27  ? 146.602 115.198 94.407  1.00 62.93  ? 27  PHE   E CE2 1 
ATOM   4680 C CZ  . PHE   D 4 27  ? 147.373 114.630 93.443  1.00 62.93  ? 27  PHE   E CZ  1 
ATOM   4681 N N   . ALA   D 4 28  ? 146.452 119.852 95.999  1.00 62.57  ? 28  ALA   E N   1 
ATOM   4682 C CA  . ALA   D 4 28  ? 146.327 119.731 97.445  1.00 62.57  ? 28  ALA   E CA  1 
ATOM   4683 C C   . ALA   D 4 28  ? 146.156 118.273 97.839  1.00 62.57  ? 28  ALA   E C   1 
ATOM   4684 O O   . ALA   D 4 28  ? 145.030 117.785 97.972  1.00 62.57  ? 28  ALA   E O   1 
ATOM   4685 C CB  . ALA   D 4 28  ? 145.151 120.563 97.951  1.00 62.57  ? 28  ALA   E CB  1 
ATOM   4686 N N   . PHE   D 4 29  ? 147.277 117.583 98.043  1.00 62.09  ? 29  PHE   E N   1 
ATOM   4687 C CA  . PHE   D 4 29  ? 147.252 116.141 98.256  1.00 62.09  ? 29  PHE   E CA  1 
ATOM   4688 C C   . PHE   D 4 29  ? 146.452 115.766 99.494  1.00 62.09  ? 29  PHE   E C   1 
ATOM   4689 O O   . PHE   D 4 29  ? 145.718 114.772 99.488  1.00 62.09  ? 29  PHE   E O   1 
ATOM   4690 C CB  . PHE   D 4 29  ? 148.683 115.623 98.366  1.00 62.09  ? 29  PHE   E CB  1 
ATOM   4691 C CG  . PHE   D 4 29  ? 148.789 114.138 98.447  1.00 62.09  ? 29  PHE   E CG  1 
ATOM   4692 C CD1 . PHE   D 4 29  ? 148.971 113.512 99.661  1.00 62.09  ? 29  PHE   E CD1 1 
ATOM   4693 C CD2 . PHE   D 4 29  ? 148.734 113.369 97.310  1.00 62.09  ? 29  PHE   E CD2 1 
ATOM   4694 C CE1 . PHE   D 4 29  ? 149.079 112.152 99.737  1.00 62.09  ? 29  PHE   E CE1 1 
ATOM   4695 C CE2 . PHE   D 4 29  ? 148.847 112.006 97.386  1.00 62.09  ? 29  PHE   E CE2 1 
ATOM   4696 C CZ  . PHE   D 4 29  ? 149.017 111.398 98.600  1.00 62.09  ? 29  PHE   E CZ  1 
ATOM   4697 N N   . SER   D 4 30  ? 146.585 116.538 100.568 1.00 61.23  ? 30  SER   E N   1 
ATOM   4698 C CA  . SER   D 4 30  ? 145.918 116.194 101.816 1.00 61.23  ? 30  SER   E CA  1 
ATOM   4699 C C   . SER   D 4 30  ? 144.403 116.290 101.718 1.00 61.23  ? 30  SER   E C   1 
ATOM   4700 O O   . SER   D 4 30  ? 143.707 115.751 102.584 1.00 61.23  ? 30  SER   E O   1 
ATOM   4701 C CB  . SER   D 4 30  ? 146.418 117.096 102.942 1.00 61.23  ? 30  SER   E CB  1 
ATOM   4702 O OG  . SER   D 4 30  ? 146.040 118.443 102.722 1.00 61.23  ? 30  SER   E OG  1 
ATOM   4703 N N   . SER   D 4 31  ? 143.876 116.956 100.695 1.00 60.23  ? 31  SER   E N   1 
ATOM   4704 C CA  . SER   D 4 31  ? 142.442 117.130 100.527 1.00 60.23  ? 31  SER   E CA  1 
ATOM   4705 C C   . SER   D 4 31  ? 141.824 116.088 99.607  1.00 60.23  ? 31  SER   E C   1 
ATOM   4706 O O   . SER   D 4 31  ? 140.647 116.205 99.259  1.00 60.23  ? 31  SER   E O   1 
ATOM   4707 C CB  . SER   D 4 31  ? 142.143 118.530 99.997  1.00 60.23  ? 31  SER   E CB  1 
ATOM   4708 O OG  . SER   D 4 31  ? 142.566 118.661 98.654  1.00 60.23  ? 31  SER   E OG  1 
ATOM   4709 N N   . PHE   D 4 32  ? 142.581 115.073 99.216  1.00 55.63  ? 32  PHE   E N   1 
ATOM   4710 C CA  . PHE   D 4 32  ? 142.153 114.109 98.219  1.00 55.63  ? 32  PHE   E CA  1 
ATOM   4711 C C   . PHE   D 4 32  ? 142.158 112.707 98.800  1.00 55.63  ? 32  PHE   E C   1 
ATOM   4712 O O   . PHE   D 4 32  ? 143.107 112.309 99.480  1.00 55.63  ? 32  PHE   E O   1 
ATOM   4713 C CB  . PHE   D 4 32  ? 143.058 114.160 96.996  1.00 55.63  ? 32  PHE   E CB  1 
ATOM   4714 C CG  . PHE   D 4 32  ? 142.655 115.185 95.995  1.00 55.63  ? 32  PHE   E CG  1 
ATOM   4715 C CD1 . PHE   D 4 32  ? 143.355 116.358 95.877  1.00 55.63  ? 32  PHE   E CD1 1 
ATOM   4716 C CD2 . PHE   D 4 32  ? 141.577 114.977 95.170  1.00 55.63  ? 32  PHE   E CD2 1 
ATOM   4717 C CE1 . PHE   D 4 32  ? 142.987 117.299 94.963  1.00 55.63  ? 32  PHE   E CE1 1 
ATOM   4718 C CE2 . PHE   D 4 32  ? 141.212 115.921 94.254  1.00 55.63  ? 32  PHE   E CE2 1 
ATOM   4719 C CZ  . PHE   D 4 32  ? 141.918 117.079 94.152  1.00 55.63  ? 32  PHE   E CZ  1 
ATOM   4720 N N   . GLY   D 4 33  ? 141.088 111.963 98.539  1.00 50.57  ? 33  GLY   E N   1 
ATOM   4721 C CA  . GLY   D 4 33  ? 141.086 110.547 98.833  1.00 50.57  ? 33  GLY   E CA  1 
ATOM   4722 C C   . GLY   D 4 33  ? 141.696 109.777 97.679  1.00 50.57  ? 33  GLY   E C   1 
ATOM   4723 O O   . GLY   D 4 33  ? 141.400 110.026 96.512  1.00 50.57  ? 33  GLY   E O   1 
ATOM   4724 N N   . MET   D 4 34  ? 142.558 108.829 98.014  1.00 50.38  ? 34  MET   E N   1 
ATOM   4725 C CA  . MET   D 4 34  ? 143.406 108.181 97.030  1.00 50.38  ? 34  MET   E CA  1 
ATOM   4726 C C   . MET   D 4 34  ? 143.190 106.675 97.054  1.00 50.38  ? 34  MET   E C   1 
ATOM   4727 O O   . MET   D 4 34  ? 143.406 106.030 98.081  1.00 50.38  ? 34  MET   E O   1 
ATOM   4728 C CB  . MET   D 4 34  ? 144.864 108.536 97.295  1.00 50.38  ? 34  MET   E CB  1 
ATOM   4729 C CG  . MET   D 4 34  ? 145.272 109.873 96.725  1.00 50.38  ? 34  MET   E CG  1 
ATOM   4730 S SD  . MET   D 4 34  ? 145.937 109.745 95.060  1.00 50.38  ? 34  MET   E SD  1 
ATOM   4731 C CE  . MET   D 4 34  ? 146.645 111.371 94.847  1.00 50.38  ? 34  MET   E CE  1 
ATOM   4732 N N   . HIS   D 4 35  ? 142.777 106.124 95.918  1.00 46.60  ? 35  HIS   E N   1 
ATOM   4733 C CA  . HIS   D 4 35  ? 142.467 104.713 95.761  1.00 46.60  ? 35  HIS   E CA  1 
ATOM   4734 C C   . HIS   D 4 35  ? 143.634 103.966 95.130  1.00 46.60  ? 35  HIS   E C   1 
ATOM   4735 O O   . HIS   D 4 35  ? 144.588 104.556 94.623  1.00 46.60  ? 35  HIS   E O   1 
ATOM   4736 C CB  . HIS   D 4 35  ? 141.231 104.517 94.883  1.00 46.60  ? 35  HIS   E CB  1 
ATOM   4737 C CG  . HIS   D 4 35  ? 140.031 105.287 95.319  1.00 46.60  ? 35  HIS   E CG  1 
ATOM   4738 N ND1 . HIS   D 4 35  ? 138.949 104.689 95.920  1.00 46.60  ? 35  HIS   E ND1 1 
ATOM   4739 C CD2 . HIS   D 4 35  ? 139.725 106.599 95.216  1.00 46.60  ? 35  HIS   E CD2 1 
ATOM   4740 C CE1 . HIS   D 4 35  ? 138.033 105.600 96.181  1.00 46.60  ? 35  HIS   E CE1 1 
ATOM   4741 N NE2 . HIS   D 4 35  ? 138.481 106.769 95.768  1.00 46.60  ? 35  HIS   E NE2 1 
ATOM   4742 N N   . TRP   D 4 36  ? 143.545 102.642 95.172  1.00 50.20  ? 36  TRP   E N   1 
ATOM   4743 C CA  . TRP   D 4 36  ? 144.445 101.756 94.448  1.00 50.20  ? 36  TRP   E CA  1 
ATOM   4744 C C   . TRP   D 4 36  ? 143.605 100.754 93.679  1.00 50.20  ? 36  TRP   E C   1 
ATOM   4745 O O   . TRP   D 4 36  ? 142.752 100.081 94.262  1.00 50.20  ? 36  TRP   E O   1 
ATOM   4746 C CB  . TRP   D 4 36  ? 145.406 101.018 95.381  1.00 50.20  ? 36  TRP   E CB  1 
ATOM   4747 C CG  . TRP   D 4 36  ? 146.570 101.813 95.871  1.00 50.20  ? 36  TRP   E CG  1 
ATOM   4748 C CD1 . TRP   D 4 36  ? 146.669 102.455 97.057  1.00 50.20  ? 36  TRP   E CD1 1 
ATOM   4749 C CD2 . TRP   D 4 36  ? 147.815 102.021 95.199  1.00 50.20  ? 36  TRP   E CD2 1 
ATOM   4750 N NE1 . TRP   D 4 36  ? 147.886 103.066 97.164  1.00 50.20  ? 36  TRP   E NE1 1 
ATOM   4751 C CE2 . TRP   D 4 36  ? 148.609 102.814 96.032  1.00 50.20  ? 36  TRP   E CE2 1 
ATOM   4752 C CE3 . TRP   D 4 36  ? 148.329 101.621 93.966  1.00 50.20  ? 36  TRP   E CE3 1 
ATOM   4753 C CZ2 . TRP   D 4 36  ? 149.888 103.213 95.679  1.00 50.20  ? 36  TRP   E CZ2 1 
ATOM   4754 C CZ3 . TRP   D 4 36  ? 149.600 102.021 93.621  1.00 50.20  ? 36  TRP   E CZ3 1 
ATOM   4755 C CH2 . TRP   D 4 36  ? 150.364 102.805 94.471  1.00 50.20  ? 36  TRP   E CH2 1 
ATOM   4756 N N   . VAL   D 4 37  ? 143.847 100.653 92.379  1.00 49.99  ? 37  VAL   E N   1 
ATOM   4757 C CA  . VAL   D 4 37  ? 143.087 99.791  91.489  1.00 49.99  ? 37  VAL   E CA  1 
ATOM   4758 C C   . VAL   D 4 37  ? 144.069 98.981  90.663  1.00 49.99  ? 37  VAL   E C   1 
ATOM   4759 O O   . VAL   D 4 37  ? 144.984 99.547  90.058  1.00 49.99  ? 37  VAL   E O   1 
ATOM   4760 C CB  . VAL   D 4 37  ? 142.155 100.604 90.575  1.00 49.99  ? 37  VAL   E CB  1 
ATOM   4761 C CG1 . VAL   D 4 37  ? 141.294 99.686  89.744  1.00 49.99  ? 37  VAL   E CG1 1 
ATOM   4762 C CG2 . VAL   D 4 37  ? 141.298 101.542 91.390  1.00 49.99  ? 37  VAL   E CG2 1 
ATOM   4763 N N   . ARG   D 4 38  ? 143.883 97.669  90.630  1.00 54.81  ? 38  ARG   E N   1 
ATOM   4764 C CA  . ARG   D 4 38  ? 144.772 96.781  89.900  1.00 54.81  ? 38  ARG   E CA  1 
ATOM   4765 C C   . ARG   D 4 38  ? 144.058 96.141  88.723  1.00 54.81  ? 38  ARG   E C   1 
ATOM   4766 O O   . ARG   D 4 38  ? 142.856 95.869  88.781  1.00 54.81  ? 38  ARG   E O   1 
ATOM   4767 C CB  . ARG   D 4 38  ? 145.333 95.692  90.805  1.00 54.81  ? 38  ARG   E CB  1 
ATOM   4768 C CG  . ARG   D 4 38  ? 144.320 94.721  91.336  1.00 54.81  ? 38  ARG   E CG  1 
ATOM   4769 C CD  . ARG   D 4 38  ? 145.006 93.762  92.272  1.00 54.81  ? 38  ARG   E CD  1 
ATOM   4770 N NE  . ARG   D 4 38  ? 144.094 92.793  92.848  1.00 54.81  ? 38  ARG   E NE  1 
ATOM   4771 C CZ  . ARG   D 4 38  ? 144.463 91.863  93.713  1.00 54.81  ? 38  ARG   E CZ  1 
ATOM   4772 N NH1 . ARG   D 4 38  ? 145.721 91.795  94.104  1.00 54.81  ? 38  ARG   E NH1 1 
ATOM   4773 N NH2 . ARG   D 4 38  ? 143.575 91.012  94.197  1.00 54.81  ? 38  ARG   E NH2 1 
ATOM   4774 N N   . GLN   D 4 39  ? 144.807 95.920  87.654  1.00 61.77  ? 39  GLN   E N   1 
ATOM   4775 C CA  . GLN   D 4 39  ? 144.321 95.264  86.453  1.00 61.77  ? 39  GLN   E CA  1 
ATOM   4776 C C   . GLN   D 4 39  ? 145.185 94.040  86.198  1.00 61.77  ? 39  GLN   E C   1 
ATOM   4777 O O   . GLN   D 4 39  ? 146.390 94.169  85.960  1.00 61.77  ? 39  GLN   E O   1 
ATOM   4778 C CB  . GLN   D 4 39  ? 144.366 96.217  85.263  1.00 61.77  ? 39  GLN   E CB  1 
ATOM   4779 C CG  . GLN   D 4 39  ? 143.628 95.732  84.041  1.00 61.77  ? 39  GLN   E CG  1 
ATOM   4780 C CD  . GLN   D 4 39  ? 143.503 96.803  82.986  1.00 61.77  ? 39  GLN   E CD  1 
ATOM   4781 O OE1 . GLN   D 4 39  ? 144.426 97.584  82.768  1.00 61.77  ? 39  GLN   E OE1 1 
ATOM   4782 N NE2 . GLN   D 4 39  ? 142.354 96.850  82.322  1.00 61.77  ? 39  GLN   E NE2 1 
ATOM   4783 N N   . ALA   D 4 40  ? 144.571 92.861  86.240  1.00 66.88  ? 40  ALA   E N   1 
ATOM   4784 C CA  . ALA   D 4 40  ? 145.298 91.633  85.996  1.00 66.88  ? 40  ALA   E CA  1 
ATOM   4785 C C   . ALA   D 4 40  ? 145.826 91.629  84.566  1.00 66.88  ? 40  ALA   E C   1 
ATOM   4786 O O   . ALA   D 4 40  ? 145.278 92.308  83.695  1.00 66.88  ? 40  ALA   E O   1 
ATOM   4787 C CB  . ALA   D 4 40  ? 144.394 90.427  86.240  1.00 66.88  ? 40  ALA   E CB  1 
ATOM   4788 N N   . PRO   D 4 41  ? 146.900 90.884  84.299  1.00 71.55  ? 41  PRO   E N   1 
ATOM   4789 C CA  . PRO   D 4 41  ? 147.473 90.897  82.944  1.00 71.55  ? 41  PRO   E CA  1 
ATOM   4790 C C   . PRO   D 4 41  ? 146.497 90.458  81.868  1.00 71.55  ? 41  PRO   E C   1 
ATOM   4791 O O   . PRO   D 4 41  ? 146.682 90.821  80.700  1.00 71.55  ? 41  PRO   E O   1 
ATOM   4792 C CB  . PRO   D 4 41  ? 148.658 89.928  83.053  1.00 71.55  ? 41  PRO   E CB  1 
ATOM   4793 C CG  . PRO   D 4 41  ? 148.994 89.903  84.501  1.00 71.55  ? 41  PRO   E CG  1 
ATOM   4794 C CD  . PRO   D 4 41  ? 147.688 90.046  85.216  1.00 71.55  ? 41  PRO   E CD  1 
ATOM   4795 N N   . GLU   D 4 42  ? 145.463 89.691  82.221  1.00 72.70  ? 42  GLU   E N   1 
ATOM   4796 C CA  . GLU   D 4 42  ? 144.445 89.277  81.269  1.00 72.70  ? 42  GLU   E CA  1 
ATOM   4797 C C   . GLU   D 4 42  ? 143.042 89.758  81.608  1.00 72.70  ? 42  GLU   E C   1 
ATOM   4798 O O   . GLU   D 4 42  ? 142.213 89.861  80.698  1.00 72.70  ? 42  GLU   E O   1 
ATOM   4799 C CB  . GLU   D 4 42  ? 144.418 87.745  81.143  1.00 72.70  ? 42  GLU   E CB  1 
ATOM   4800 N N   . LYS   D 4 43  ? 142.753 90.058  82.870  1.00 68.03  ? 43  LYS   E N   1 
ATOM   4801 C CA  . LYS   D 4 43  ? 141.417 90.452  83.290  1.00 68.03  ? 43  LYS   E CA  1 
ATOM   4802 C C   . LYS   D 4 43  ? 141.270 91.973  83.228  1.00 68.03  ? 43  LYS   E C   1 
ATOM   4803 O O   . LYS   D 4 43  ? 142.080 92.676  82.619  1.00 68.03  ? 43  LYS   E O   1 
ATOM   4804 C CB  . LYS   D 4 43  ? 141.122 89.901  84.682  1.00 68.03  ? 43  LYS   E CB  1 
ATOM   4805 N N   . GLY   D 4 44  ? 140.216 92.491  83.842  1.00 64.23  ? 44  GLY   E N   1 
ATOM   4806 C CA  . GLY   D 4 44  ? 139.903 93.909  83.873  1.00 64.23  ? 44  GLY   E CA  1 
ATOM   4807 C C   . GLY   D 4 44  ? 140.301 94.560  85.180  1.00 64.23  ? 44  GLY   E C   1 
ATOM   4808 O O   . GLY   D 4 44  ? 141.341 94.240  85.764  1.00 64.23  ? 44  GLY   E O   1 
ATOM   4809 N N   . LEU   D 4 45  ? 139.456 95.470  85.655  1.00 57.67  ? 45  LEU   E N   1 
ATOM   4810 C CA  . LEU   D 4 45  ? 139.801 96.364  86.752  1.00 57.67  ? 45  LEU   E CA  1 
ATOM   4811 C C   . LEU   D 4 45  ? 139.169 95.887  88.049  1.00 57.67  ? 45  LEU   E C   1 
ATOM   4812 O O   . LEU   D 4 45  ? 137.980 95.559  88.084  1.00 57.67  ? 45  LEU   E O   1 
ATOM   4813 C CB  . LEU   D 4 45  ? 139.354 97.790  86.446  1.00 57.67  ? 45  LEU   E CB  1 
ATOM   4814 C CG  . LEU   D 4 45  ? 140.232 98.593  85.492  1.00 57.67  ? 45  LEU   E CG  1 
ATOM   4815 C CD1 . LEU   D 4 45  ? 139.574 99.915  85.169  1.00 57.67  ? 45  LEU   E CD1 1 
ATOM   4816 C CD2 . LEU   D 4 45  ? 141.595 98.814  86.093  1.00 57.67  ? 45  LEU   E CD2 1 
ATOM   4817 N N   . GLU   D 4 46  ? 139.971 95.852  89.111  1.00 54.98  ? 46  GLU   E N   1 
ATOM   4818 C CA  . GLU   D 4 46  ? 139.536 95.389  90.421  1.00 54.98  ? 46  GLU   E CA  1 
ATOM   4819 C C   . GLU   D 4 46  ? 140.042 96.347  91.484  1.00 54.98  ? 46  GLU   E C   1 
ATOM   4820 O O   . GLU   D 4 46  ? 141.218 96.718  91.479  1.00 54.98  ? 46  GLU   E O   1 
ATOM   4821 C CB  . GLU   D 4 46  ? 140.045 93.972  90.697  1.00 54.98  ? 46  GLU   E CB  1 
ATOM   4822 C CG  . GLU   D 4 46  ? 139.714 93.453  92.086  1.00 54.98  ? 46  GLU   E CG  1 
ATOM   4823 C CD  . GLU   D 4 46  ? 140.541 92.241  92.471  1.00 54.98  ? 46  GLU   E CD  1 
ATOM   4824 O OE1 . GLU   D 4 46  ? 141.352 91.784  91.638  1.00 54.98  ? 46  GLU   E OE1 1 
ATOM   4825 O OE2 . GLU   D 4 46  ? 140.380 91.747  93.607  1.00 54.98  ? 46  GLU   E OE2 1 
ATOM   4826 N N   . TRP   D 4 47  ? 139.158 96.741  92.389  1.00 47.49  ? 47  TRP   E N   1 
ATOM   4827 C CA  . TRP   D 4 47  ? 139.493 97.680  93.447  1.00 47.49  ? 47  TRP   E CA  1 
ATOM   4828 C C   . TRP   D 4 47  ? 140.304 96.987  94.535  1.00 47.49  ? 47  TRP   E C   1 
ATOM   4829 O O   . TRP   D 4 47  ? 140.080 95.812  94.835  1.00 47.49  ? 47  TRP   E O   1 
ATOM   4830 C CB  . TRP   D 4 47  ? 138.202 98.262  94.013  1.00 47.49  ? 47  TRP   E CB  1 
ATOM   4831 C CG  . TRP   D 4 47  ? 138.335 99.322  95.020  1.00 47.49  ? 47  TRP   E CG  1 
ATOM   4832 C CD1 . TRP   D 4 47  ? 138.763 100.583 94.820  1.00 47.49  ? 47  TRP   E CD1 1 
ATOM   4833 C CD2 . TRP   D 4 47  ? 137.997 99.223  96.396  1.00 47.49  ? 47  TRP   E CD2 1 
ATOM   4834 N NE1 . TRP   D 4 47  ? 138.726 101.283 95.990  1.00 47.49  ? 47  TRP   E NE1 1 
ATOM   4835 C CE2 . TRP   D 4 47  ? 138.248 100.465 96.974  1.00 47.49  ? 47  TRP   E CE2 1 
ATOM   4836 C CE3 . TRP   D 4 47  ? 137.493 98.200  97.195  1.00 47.49  ? 47  TRP   E CE3 1 
ATOM   4837 C CZ2 . TRP   D 4 47  ? 138.038 100.710 98.314  1.00 47.49  ? 47  TRP   E CZ2 1 
ATOM   4838 C CZ3 . TRP   D 4 47  ? 137.280 98.446  98.517  1.00 47.49  ? 47  TRP   E CZ3 1 
ATOM   4839 C CH2 . TRP   D 4 47  ? 137.549 99.687  99.067  1.00 47.49  ? 47  TRP   E CH2 1 
ATOM   4840 N N   . VAL   D 4 48  ? 141.257 97.715  95.126  1.00 46.89  ? 48  VAL   E N   1 
ATOM   4841 C CA  . VAL   D 4 48  ? 142.133 97.133  96.141  1.00 46.89  ? 48  VAL   E CA  1 
ATOM   4842 C C   . VAL   D 4 48  ? 141.967 97.812  97.494  1.00 46.89  ? 48  VAL   E C   1 
ATOM   4843 O O   . VAL   D 4 48  ? 141.519 97.184  98.457  1.00 46.89  ? 48  VAL   E O   1 
ATOM   4844 C CB  . VAL   D 4 48  ? 143.604 97.191  95.701  1.00 46.89  ? 48  VAL   E CB  1 
ATOM   4845 C CG1 . VAL   D 4 48  ? 144.505 96.800  96.847  1.00 46.89  ? 48  VAL   E CG1 1 
ATOM   4846 C CG2 . VAL   D 4 48  ? 143.832 96.282  94.542  1.00 46.89  ? 48  VAL   E CG2 1 
ATOM   4847 N N   . ALA   D 4 49  ? 142.311 99.092  97.583  1.00 43.29  ? 49  ALA   E N   1 
ATOM   4848 C CA  . ALA   D 4 49  ? 142.318 99.790  98.857  1.00 43.29  ? 49  ALA   E CA  1 
ATOM   4849 C C   . ALA   D 4 49  ? 141.809 101.210 98.676  1.00 43.29  ? 49  ALA   E C   1 
ATOM   4850 O O   . ALA   D 4 49  ? 141.553 101.663 97.560  1.00 43.29  ? 49  ALA   E O   1 
ATOM   4851 C CB  . ALA   D 4 49  ? 143.716 99.799  99.479  1.00 43.29  ? 49  ALA   E CB  1 
ATOM   4852 N N   . TYR   D 4 50  ? 141.664 101.913 99.795  1.00 44.85  ? 50  TYR   E N   1 
ATOM   4853 C CA  . TYR   D 4 50  ? 141.238 103.307 99.796  1.00 44.85  ? 50  TYR   E CA  1 
ATOM   4854 C C   . TYR   D 4 50  ? 141.685 103.970 101.088 1.00 44.85  ? 50  TYR   E C   1 
ATOM   4855 O O   . TYR   D 4 50  ? 141.465 103.422 102.171 1.00 44.85  ? 50  TYR   E O   1 
ATOM   4856 C CB  . TYR   D 4 50  ? 139.728 103.423 99.649  1.00 44.85  ? 50  TYR   E CB  1 
ATOM   4857 C CG  . TYR   D 4 50  ? 139.176 104.803 99.889  1.00 44.85  ? 50  TYR   E CG  1 
ATOM   4858 C CD1 . TYR   D 4 50  ? 139.527 105.862 99.079  1.00 44.85  ? 50  TYR   E CD1 1 
ATOM   4859 C CD2 . TYR   D 4 50  ? 138.288 105.040 100.905 1.00 44.85  ? 50  TYR   E CD2 1 
ATOM   4860 C CE1 . TYR   D 4 50  ? 139.013 107.118 99.293  1.00 44.85  ? 50  TYR   E CE1 1 
ATOM   4861 C CE2 . TYR   D 4 50  ? 137.777 106.284 101.124 1.00 44.85  ? 50  TYR   E CE2 1 
ATOM   4862 C CZ  . TYR   D 4 50  ? 138.140 107.317 100.321 1.00 44.85  ? 50  TYR   E CZ  1 
ATOM   4863 O OH  . TYR   D 4 50  ? 137.608 108.558 100.560 1.00 44.85  ? 50  TYR   E OH  1 
ATOM   4864 N N   . ILE   D 4 51  ? 142.309 105.139 100.972 1.00 50.37  ? 51  ILE   E N   1 
ATOM   4865 C CA  . ILE   D 4 51  ? 142.719 105.942 102.117 1.00 50.37  ? 51  ILE   E CA  1 
ATOM   4866 C C   . ILE   D 4 51  ? 142.166 107.347 101.937 1.00 50.37  ? 51  ILE   E C   1 
ATOM   4867 O O   . ILE   D 4 51  ? 142.301 107.941 100.862 1.00 50.37  ? 51  ILE   E O   1 
ATOM   4868 C CB  . ILE   D 4 51  ? 144.249 105.956 102.285 1.00 50.37  ? 51  ILE   E CB  1 
ATOM   4869 C CG1 . ILE   D 4 51  ? 144.649 106.742 103.525 1.00 50.37  ? 51  ILE   E CG1 1 
ATOM   4870 C CG2 . ILE   D 4 51  ? 144.931 106.505 101.056 1.00 50.37  ? 51  ILE   E CG2 1 
ATOM   4871 C CD1 . ILE   D 4 51  ? 144.320 106.052 104.814 1.00 50.37  ? 51  ILE   E CD1 1 
ATOM   4872 N N   . SER   D 4 52  ? 141.523 107.867 102.973 1.00 53.49  ? 52  SER   E N   1 
ATOM   4873 C CA  . SER   D 4 52  ? 140.760 109.096 102.853 1.00 53.49  ? 52  SER   E CA  1 
ATOM   4874 C C   . SER   D 4 52  ? 141.639 110.323 103.040 1.00 53.49  ? 52  SER   E C   1 
ATOM   4875 O O   . SER   D 4 52  ? 142.852 110.236 103.248 1.00 53.49  ? 52  SER   E O   1 
ATOM   4876 C CB  . SER   D 4 52  ? 139.627 109.119 103.865 1.00 53.49  ? 52  SER   E CB  1 
ATOM   4877 O OG  . SER   D 4 52  ? 139.195 110.445 104.090 1.00 53.49  ? 52  SER   E OG  1 
ATOM   4878 N N   . SER   D 4 53  ? 141.010 111.490 102.964 1.00 57.35  ? 53  SER   E N   1 
ATOM   4879 C CA  . SER   D 4 53  ? 141.680 112.724 103.341 1.00 57.35  ? 53  SER   E CA  1 
ATOM   4880 C C   . SER   D 4 53  ? 141.883 112.751 104.849 1.00 57.35  ? 53  SER   E C   1 
ATOM   4881 O O   . SER   D 4 53  ? 140.950 112.498 105.617 1.00 57.35  ? 53  SER   E O   1 
ATOM   4882 C CB  . SER   D 4 53  ? 140.862 113.929 102.894 1.00 57.35  ? 53  SER   E CB  1 
ATOM   4883 O OG  . SER   D 4 53  ? 141.465 115.137 103.321 1.00 57.35  ? 53  SER   E OG  1 
ATOM   4884 N N   . GLY   D 4 54  ? 143.104 113.054 105.275 1.00 60.16  ? 54  GLY   E N   1 
ATOM   4885 C CA  . GLY   D 4 54  ? 143.421 113.035 106.684 1.00 60.16  ? 54  GLY   E CA  1 
ATOM   4886 C C   . GLY   D 4 54  ? 143.668 111.665 107.267 1.00 60.16  ? 54  GLY   E C   1 
ATOM   4887 O O   . GLY   D 4 54  ? 143.719 111.538 108.495 1.00 60.16  ? 54  GLY   E O   1 
ATOM   4888 N N   . SER   D 4 55  ? 143.828 110.641 106.428 1.00 60.26  ? 55  SER   E N   1 
ATOM   4889 C CA  . SER   D 4 55  ? 144.047 109.268 106.882 1.00 60.26  ? 55  SER   E CA  1 
ATOM   4890 C C   . SER   D 4 55  ? 142.946 108.824 107.841 1.00 60.26  ? 55  SER   E C   1 
ATOM   4891 O O   . SER   D 4 55  ? 143.194 108.133 108.829 1.00 60.26  ? 55  SER   E O   1 
ATOM   4892 C CB  . SER   D 4 55  ? 145.426 109.114 107.526 1.00 60.26  ? 55  SER   E CB  1 
ATOM   4893 O OG  . SER   D 4 55  ? 146.448 109.588 106.666 1.00 60.26  ? 55  SER   E OG  1 
ATOM   4894 N N   . GLY   D 4 56  ? 141.714 109.217 107.539 1.00 58.02  ? 56  GLY   E N   1 
ATOM   4895 C CA  . GLY   D 4 56  ? 140.604 108.944 108.425 1.00 58.02  ? 56  GLY   E CA  1 
ATOM   4896 C C   . GLY   D 4 56  ? 139.954 107.590 108.240 1.00 58.02  ? 56  GLY   E C   1 
ATOM   4897 O O   . GLY   D 4 56  ? 139.916 106.789 109.177 1.00 58.02  ? 56  GLY   E O   1 
ATOM   4898 N N   . THR   D 4 57  ? 139.443 107.316 107.044 1.00 53.80  ? 57  THR   E N   1 
ATOM   4899 C CA  . THR   D 4 57  ? 138.760 106.064 106.752 1.00 53.80  ? 57  THR   E CA  1 
ATOM   4900 C C   . THR   D 4 57  ? 139.584 105.228 105.790 1.00 53.80  ? 57  THR   E C   1 
ATOM   4901 O O   . THR   D 4 57  ? 140.139 105.744 104.817 1.00 53.80  ? 57  THR   E O   1 
ATOM   4902 C CB  . THR   D 4 57  ? 137.367 106.302 106.166 1.00 53.80  ? 57  THR   E CB  1 
ATOM   4903 O OG1 . THR   D 4 57  ? 137.447 107.237 105.085 1.00 53.80  ? 57  THR   E OG1 1 
ATOM   4904 C CG2 . THR   D 4 57  ? 136.422 106.828 107.225 1.00 53.80  ? 57  THR   E CG2 1 
ATOM   4905 N N   . ILE   D 4 58  ? 139.665 103.936 106.078 1.00 49.17  ? 58  ILE   E N   1 
ATOM   4906 C CA  . ILE   D 4 58  ? 140.444 102.990 105.298 1.00 49.17  ? 58  ILE   E CA  1 
ATOM   4907 C C   . ILE   D 4 58  ? 139.548 101.816 104.941 1.00 49.17  ? 58  ILE   E C   1 
ATOM   4908 O O   . ILE   D 4 58  ? 138.877 101.256 105.815 1.00 49.17  ? 58  ILE   E O   1 
ATOM   4909 C CB  . ILE   D 4 58  ? 141.681 102.510 106.071 1.00 49.17  ? 58  ILE   E CB  1 
ATOM   4910 C CG1 . ILE   D 4 58  ? 142.386 103.688 106.729 1.00 49.17  ? 58  ILE   E CG1 1 
ATOM   4911 C CG2 . ILE   D 4 58  ? 142.621 101.837 105.153 1.00 49.17  ? 58  ILE   E CG2 1 
ATOM   4912 C CD1 . ILE   D 4 58  ? 143.658 103.312 107.455 1.00 49.17  ? 58  ILE   E CD1 1 
ATOM   4913 N N   . TYR   D 4 59  ? 139.533 101.446 103.666 1.00 48.77  ? 59  TYR   E N   1 
ATOM   4914 C CA  . TYR   D 4 59  ? 138.735 100.336 103.171 1.00 48.77  ? 59  TYR   E CA  1 
ATOM   4915 C C   . TYR   D 4 59  ? 139.614 99.408  102.354 1.00 48.77  ? 59  TYR   E C   1 
ATOM   4916 O O   . TYR   D 4 59  ? 140.466 99.866  101.588 1.00 48.77  ? 59  TYR   E O   1 
ATOM   4917 C CB  . TYR   D 4 59  ? 137.580 100.822 102.313 1.00 48.77  ? 59  TYR   E CB  1 
ATOM   4918 C CG  . TYR   D 4 59  ? 136.500 101.525 103.077 1.00 48.77  ? 59  TYR   E CG  1 
ATOM   4919 C CD1 . TYR   D 4 59  ? 135.571 100.812 103.816 1.00 48.77  ? 59  TYR   E CD1 1 
ATOM   4920 C CD2 . TYR   D 4 59  ? 136.400 102.898 103.059 1.00 48.77  ? 59  TYR   E CD2 1 
ATOM   4921 C CE1 . TYR   D 4 59  ? 134.578 101.457 104.515 1.00 48.77  ? 59  TYR   E CE1 1 
ATOM   4922 C CE2 . TYR   D 4 59  ? 135.417 103.545 103.757 1.00 48.77  ? 59  TYR   E CE2 1 
ATOM   4923 C CZ  . TYR   D 4 59  ? 134.509 102.824 104.479 1.00 48.77  ? 59  TYR   E CZ  1 
ATOM   4924 O OH  . TYR   D 4 59  ? 133.520 103.473 105.177 1.00 48.77  ? 59  TYR   E OH  1 
ATOM   4925 N N   . TYR   D 4 60  ? 139.409 98.109  102.517 1.00 52.98  ? 60  TYR   E N   1 
ATOM   4926 C CA  . TYR   D 4 60  ? 140.141 97.113  101.757 1.00 52.98  ? 60  TYR   E CA  1 
ATOM   4927 C C   . TYR   D 4 60  ? 139.161 96.164  101.091 1.00 52.98  ? 60  TYR   E C   1 
ATOM   4928 O O   . TYR   D 4 60  ? 138.014 96.021  101.516 1.00 52.98  ? 60  TYR   E O   1 
ATOM   4929 C CB  . TYR   D 4 60  ? 141.103 96.314  102.632 1.00 52.98  ? 60  TYR   E CB  1 
ATOM   4930 C CG  . TYR   D 4 60  ? 142.266 97.102  103.147 1.00 52.98  ? 60  TYR   E CG  1 
ATOM   4931 C CD1 . TYR   D 4 60  ? 142.159 97.843  104.301 1.00 52.98  ? 60  TYR   E CD1 1 
ATOM   4932 C CD2 . TYR   D 4 60  ? 143.473 97.096  102.488 1.00 52.98  ? 60  TYR   E CD2 1 
ATOM   4933 C CE1 . TYR   D 4 60  ? 143.214 98.560  104.780 1.00 52.98  ? 60  TYR   E CE1 1 
ATOM   4934 C CE2 . TYR   D 4 60  ? 144.538 97.815  102.960 1.00 52.98  ? 60  TYR   E CE2 1 
ATOM   4935 C CZ  . TYR   D 4 60  ? 144.400 98.550  104.107 1.00 52.98  ? 60  TYR   E CZ  1 
ATOM   4936 O OH  . TYR   D 4 60  ? 145.461 99.273  104.595 1.00 52.98  ? 60  TYR   E OH  1 
ATOM   4937 N N   . ALA   D 4 61  ? 139.622 95.524  100.026 1.00 58.86  ? 61  ALA   E N   1 
ATOM   4938 C CA  . ALA   D 4 61  ? 138.825 94.479  99.422  1.00 58.86  ? 61  ALA   E CA  1 
ATOM   4939 C C   . ALA   D 4 61  ? 138.882 93.228  100.289 1.00 58.86  ? 61  ALA   E C   1 
ATOM   4940 O O   . ALA   D 4 61  ? 139.787 93.047  101.108 1.00 58.86  ? 61  ALA   E O   1 
ATOM   4941 C CB  . ALA   D 4 61  ? 139.311 94.170  98.010  1.00 58.86  ? 61  ALA   E CB  1 
ATOM   4942 N N   . ASP   D 4 62  ? 137.889 92.359  100.109 1.00 66.92  ? 62  ASP   E N   1 
ATOM   4943 C CA  . ASP   D 4 62  ? 137.850 91.127  100.881 1.00 66.92  ? 62  ASP   E CA  1 
ATOM   4944 C C   . ASP   D 4 62  ? 139.015 90.204  100.556 1.00 66.92  ? 62  ASP   E C   1 
ATOM   4945 O O   . ASP   D 4 62  ? 139.339 89.331  101.367 1.00 66.92  ? 62  ASP   E O   1 
ATOM   4946 C CB  . ASP   D 4 62  ? 136.527 90.399  100.643 1.00 66.92  ? 62  ASP   E CB  1 
ATOM   4947 C CG  . ASP   D 4 62  ? 135.329 91.200  101.113 1.00 66.92  ? 62  ASP   E CG  1 
ATOM   4948 O OD1 . ASP   D 4 62  ? 135.484 92.011  102.051 1.00 66.92  ? 62  ASP   E OD1 1 
ATOM   4949 O OD2 . ASP   D 4 62  ? 134.231 91.020  100.545 1.00 66.92  ? 62  ASP   E OD2 1 
ATOM   4950 N N   . THR   D 4 63  ? 139.649 90.373  99.402  1.00 66.47  ? 63  THR   E N   1 
ATOM   4951 C CA  . THR   D 4 63  ? 140.726 89.492  98.981  1.00 66.47  ? 63  THR   E CA  1 
ATOM   4952 C C   . THR   D 4 63  ? 142.108 89.994  99.373  1.00 66.47  ? 63  THR   E C   1 
ATOM   4953 O O   . THR   D 4 63  ? 143.092 89.290  99.134  1.00 66.47  ? 63  THR   E O   1 
ATOM   4954 C CB  . THR   D 4 63  ? 140.677 89.284  97.468  1.00 66.47  ? 63  THR   E CB  1 
ATOM   4955 O OG1 . THR   D 4 63  ? 141.634 88.287  97.094  1.00 66.47  ? 63  THR   E OG1 1 
ATOM   4956 C CG2 . THR   D 4 63  ? 140.994 90.580  96.743  1.00 66.47  ? 63  THR   E CG2 1 
ATOM   4957 N N   . VAL   D 4 64  ? 142.215 91.189  99.947  1.00 62.55  ? 64  VAL   E N   1 
ATOM   4958 C CA  . VAL   D 4 64  ? 143.509 91.723  100.356 1.00 62.55  ? 64  VAL   E CA  1 
ATOM   4959 C C   . VAL   D 4 64  ? 143.449 92.256  101.779 1.00 62.55  ? 64  VAL   E C   1 
ATOM   4960 O O   . VAL   D 4 64  ? 144.255 93.109  102.162 1.00 62.55  ? 64  VAL   E O   1 
ATOM   4961 C CB  . VAL   D 4 64  ? 143.994 92.822  99.398  1.00 62.55  ? 64  VAL   E CB  1 
ATOM   4962 C CG1 . VAL   D 4 64  ? 144.146 92.276  98.000  1.00 62.55  ? 64  VAL   E CG1 1 
ATOM   4963 C CG2 . VAL   D 4 64  ? 143.033 93.986  99.407  1.00 62.55  ? 64  VAL   E CG2 1 
ATOM   4964 N N   . LYS   D 4 65  ? 142.507 91.765  102.573 1.00 65.35  ? 65  LYS   E N   1 
ATOM   4965 C CA  . LYS   D 4 65  ? 142.402 92.186  103.962 1.00 65.35  ? 65  LYS   E CA  1 
ATOM   4966 C C   . LYS   D 4 65  ? 143.353 91.354  104.809 1.00 65.35  ? 65  LYS   E C   1 
ATOM   4967 O O   . LYS   D 4 65  ? 143.353 90.122  104.729 1.00 65.35  ? 65  LYS   E O   1 
ATOM   4968 C CB  . LYS   D 4 65  ? 140.971 92.050  104.474 1.00 65.35  ? 65  LYS   E CB  1 
ATOM   4969 C CG  . LYS   D 4 65  ? 140.535 93.192  105.371 1.00 65.35  ? 65  LYS   E CG  1 
ATOM   4970 C CD  . LYS   D 4 65  ? 139.039 93.172  105.600 1.00 65.35  ? 65  LYS   E CD  1 
ATOM   4971 C CE  . LYS   D 4 65  ? 138.283 93.412  104.308 1.00 65.35  ? 65  LYS   E CE  1 
ATOM   4972 N NZ  . LYS   D 4 65  ? 136.815 93.527  104.535 1.00 65.35  ? 65  LYS   E NZ  1 
ATOM   4973 N N   . GLY   D 4 66  ? 144.164 92.030  105.614 1.00 67.49  ? 66  GLY   E N   1 
ATOM   4974 C CA  . GLY   D 4 66  ? 145.176 91.368  106.400 1.00 67.49  ? 66  GLY   E CA  1 
ATOM   4975 C C   . GLY   D 4 66  ? 146.473 91.112  105.675 1.00 67.49  ? 66  GLY   E C   1 
ATOM   4976 O O   . GLY   D 4 66  ? 147.392 90.534  106.269 1.00 67.49  ? 66  GLY   E O   1 
ATOM   4977 N N   . ARG   D 4 67  ? 146.581 91.520  104.415 1.00 68.80  ? 67  ARG   E N   1 
ATOM   4978 C CA  . ARG   D 4 67  ? 147.793 91.343  103.639 1.00 68.80  ? 67  ARG   E CA  1 
ATOM   4979 C C   . ARG   D 4 67  ? 148.335 92.632  103.055 1.00 68.80  ? 67  ARG   E C   1 
ATOM   4980 O O   . ARG   D 4 67  ? 149.512 92.672  102.688 1.00 68.80  ? 67  ARG   E O   1 
ATOM   4981 C CB  . ARG   D 4 67  ? 147.552 90.352  102.492 1.00 68.80  ? 67  ARG   E CB  1 
ATOM   4982 C CG  . ARG   D 4 67  ? 146.960 89.038  102.937 1.00 68.80  ? 67  ARG   E CG  1 
ATOM   4983 C CD  . ARG   D 4 67  ? 146.395 88.298  101.762 1.00 68.80  ? 67  ARG   E CD  1 
ATOM   4984 N NE  . ARG   D 4 67  ? 147.248 88.463  100.595 1.00 68.80  ? 67  ARG   E NE  1 
ATOM   4985 C CZ  . ARG   D 4 67  ? 146.820 88.380  99.343  1.00 68.80  ? 67  ARG   E CZ  1 
ATOM   4986 N NH1 . ARG   D 4 67  ? 145.545 88.125  99.093  1.00 68.80  ? 67  ARG   E NH1 1 
ATOM   4987 N NH2 . ARG   D 4 67  ? 147.668 88.551  98.342  1.00 68.80  ? 67  ARG   E NH2 1 
ATOM   4988 N N   . PHE   D 4 68  ? 147.523 93.677  102.956 1.00 61.73  ? 68  PHE   E N   1 
ATOM   4989 C CA  . PHE   D 4 68  ? 147.944 94.953  102.409 1.00 61.73  ? 68  PHE   E CA  1 
ATOM   4990 C C   . PHE   D 4 68  ? 147.784 96.035  103.463 1.00 61.73  ? 68  PHE   E C   1 
ATOM   4991 O O   . PHE   D 4 68  ? 146.911 95.956  104.328 1.00 61.73  ? 68  PHE   E O   1 
ATOM   4992 C CB  . PHE   D 4 68  ? 147.135 95.331  101.163 1.00 61.73  ? 68  PHE   E CB  1 
ATOM   4993 C CG  . PHE   D 4 68  ? 147.546 94.604  99.915  1.00 61.73  ? 68  PHE   E CG  1 
ATOM   4994 C CD1 . PHE   D 4 68  ? 146.913 94.861  98.723  1.00 61.73  ? 68  PHE   E CD1 1 
ATOM   4995 C CD2 . PHE   D 4 68  ? 148.550 93.669  99.931  1.00 61.73  ? 68  PHE   E CD2 1 
ATOM   4996 C CE1 . PHE   D 4 68  ? 147.276 94.201  97.580  1.00 61.73  ? 68  PHE   E CE1 1 
ATOM   4997 C CE2 . PHE   D 4 68  ? 148.907 93.006  98.789  1.00 61.73  ? 68  PHE   E CE2 1 
ATOM   4998 C CZ  . PHE   D 4 68  ? 148.276 93.275  97.618  1.00 61.73  ? 68  PHE   E CZ  1 
ATOM   4999 N N   . THR   D 4 69  ? 148.641 97.047  103.384 1.00 63.45  ? 69  THR   E N   1 
ATOM   5000 C CA  . THR   D 4 69  ? 148.568 98.216  104.247 1.00 63.45  ? 69  THR   E CA  1 
ATOM   5001 C C   . THR   D 4 69  ? 148.674 99.463  103.385 1.00 63.45  ? 69  THR   E C   1 
ATOM   5002 O O   . THR   D 4 69  ? 149.535 99.537  102.506 1.00 63.45  ? 69  THR   E O   1 
ATOM   5003 C CB  . THR   D 4 69  ? 149.680 98.202  105.300 1.00 63.45  ? 69  THR   E CB  1 
ATOM   5004 O OG1 . THR   D 4 69  ? 149.594 96.998  106.072 1.00 63.45  ? 69  THR   E OG1 1 
ATOM   5005 C CG2 . THR   D 4 69  ? 149.555 99.401  106.229 1.00 63.45  ? 69  THR   E CG2 1 
ATOM   5006 N N   . ILE   D 4 70  ? 147.804 100.436 103.637 1.00 57.17  ? 70  ILE   E N   1 
ATOM   5007 C CA  . ILE   D 4 70  ? 147.770 101.679 102.879 1.00 57.17  ? 70  ILE   E CA  1 
ATOM   5008 C C   . ILE   D 4 70  ? 147.999 102.836 103.840 1.00 57.17  ? 70  ILE   E C   1 
ATOM   5009 O O   . ILE   D 4 70  ? 147.400 102.889 104.919 1.00 57.17  ? 70  ILE   E O   1 
ATOM   5010 C CB  . ILE   D 4 70  ? 146.452 101.831 102.094 1.00 57.17  ? 70  ILE   E CB  1 
ATOM   5011 C CG1 . ILE   D 4 70  ? 146.558 102.936 101.053 1.00 57.17  ? 70  ILE   E CG1 1 
ATOM   5012 C CG2 . ILE   D 4 70  ? 145.284 102.088 103.002 1.00 57.17  ? 70  ILE   E CG2 1 
ATOM   5013 C CD1 . ILE   D 4 70  ? 145.358 103.026 100.178 1.00 57.17  ? 70  ILE   E CD1 1 
ATOM   5014 N N   . SER   D 4 71  ? 148.907 103.732 103.469 1.00 61.32  ? 71  SER   E N   1 
ATOM   5015 C CA  . SER   D 4 71  ? 149.281 104.844 104.325 1.00 61.32  ? 71  SER   E CA  1 
ATOM   5016 C C   . SER   D 4 71  ? 149.845 105.950 103.454 1.00 61.32  ? 71  SER   E C   1 
ATOM   5017 O O   . SER   D 4 71  ? 150.518 105.678 102.460 1.00 61.32  ? 71  SER   E O   1 
ATOM   5018 C CB  . SER   D 4 71  ? 150.308 104.417 105.378 1.00 61.32  ? 71  SER   E CB  1 
ATOM   5019 O OG  . SER   D 4 71  ? 151.537 104.053 104.772 1.00 61.32  ? 71  SER   E OG  1 
ATOM   5020 N N   . ARG   D 4 72  ? 149.580 107.190 103.840 1.00 62.34  ? 72  ARG   E N   1 
ATOM   5021 C CA  . ARG   D 4 72  ? 149.976 108.350 103.063 1.00 62.34  ? 72  ARG   E CA  1 
ATOM   5022 C C   . ARG   D 4 72  ? 150.888 109.243 103.888 1.00 62.34  ? 72  ARG   E C   1 
ATOM   5023 O O   . ARG   D 4 72  ? 150.791 109.295 105.117 1.00 62.34  ? 72  ARG   E O   1 
ATOM   5024 C CB  . ARG   D 4 72  ? 148.756 109.143 102.601 1.00 62.34  ? 72  ARG   E CB  1 
ATOM   5025 C CG  . ARG   D 4 72  ? 147.828 109.556 103.708 1.00 62.34  ? 72  ARG   E CG  1 
ATOM   5026 C CD  . ARG   D 4 72  ? 146.502 110.012 103.157 1.00 62.34  ? 72  ARG   E CD  1 
ATOM   5027 N NE  . ARG   D 4 72  ? 146.659 110.791 101.937 1.00 62.34  ? 72  ARG   E NE  1 
ATOM   5028 C CZ  . ARG   D 4 72  ? 145.736 111.610 101.450 1.00 62.34  ? 72  ARG   E CZ  1 
ATOM   5029 N NH1 . ARG   D 4 72  ? 144.587 111.760 102.080 1.00 62.34  ? 72  ARG   E NH1 1 
ATOM   5030 N NH2 . ARG   D 4 72  ? 145.964 112.278 100.333 1.00 62.34  ? 72  ARG   E NH2 1 
ATOM   5031 N N   . ASP   D 4 73  ? 151.775 109.948 103.201 1.00 72.18  ? 73  ASP   E N   1 
ATOM   5032 C CA  . ASP   D 4 73  ? 152.710 110.877 103.824 1.00 72.18  ? 73  ASP   E CA  1 
ATOM   5033 C C   . ASP   D 4 73  ? 152.348 112.274 103.336 1.00 72.18  ? 73  ASP   E C   1 
ATOM   5034 O O   . ASP   D 4 73  ? 152.827 112.726 102.296 1.00 72.18  ? 73  ASP   E O   1 
ATOM   5035 C CB  . ASP   D 4 73  ? 154.152 110.518 103.482 1.00 72.18  ? 73  ASP   E CB  1 
ATOM   5036 C CG  . ASP   D 4 73  ? 155.125 110.903 104.578 1.00 72.18  ? 73  ASP   E CG  1 
ATOM   5037 O OD1 . ASP   D 4 73  ? 156.040 110.105 104.870 1.00 72.18  ? 73  ASP   E OD1 1 
ATOM   5038 O OD2 . ASP   D 4 73  ? 154.977 112.004 105.148 1.00 72.18  ? 73  ASP   E OD2 1 
ATOM   5039 N N   . ASP   D 4 74  ? 151.486 112.950 104.091 1.00 73.45  ? 74  ASP   E N   1 
ATOM   5040 C CA  . ASP   D 4 74  ? 151.054 114.288 103.700 1.00 73.45  ? 74  ASP   E CA  1 
ATOM   5041 C C   . ASP   D 4 74  ? 152.203 115.275 103.525 1.00 73.45  ? 74  ASP   E C   1 
ATOM   5042 O O   . ASP   D 4 74  ? 152.166 116.046 102.550 1.00 73.45  ? 74  ASP   E O   1 
ATOM   5043 C CB  . ASP   D 4 74  ? 150.030 114.813 104.712 1.00 73.45  ? 74  ASP   E CB  1 
ATOM   5044 C CG  . ASP   D 4 74  ? 148.616 114.399 104.374 1.00 73.45  ? 74  ASP   E CG  1 
ATOM   5045 O OD1 . ASP   D 4 74  ? 148.308 114.262 103.173 1.00 73.45  ? 74  ASP   E OD1 1 
ATOM   5046 O OD2 . ASP   D 4 74  ? 147.811 114.208 105.309 1.00 73.45  ? 74  ASP   E OD2 1 
ATOM   5047 N N   . PRO   D 4 75  ? 153.225 115.333 104.406 1.00 75.91  ? 75  PRO   E N   1 
ATOM   5048 C CA  . PRO   D 4 75  ? 154.342 116.255 104.157 1.00 75.91  ? 75  PRO   E CA  1 
ATOM   5049 C C   . PRO   D 4 75  ? 155.049 116.015 102.833 1.00 75.91  ? 75  PRO   E C   1 
ATOM   5050 O O   . PRO   D 4 75  ? 155.141 116.928 102.006 1.00 75.91  ? 75  PRO   E O   1 
ATOM   5051 C CB  . PRO   D 4 75  ? 155.280 115.989 105.340 1.00 75.91  ? 75  PRO   E CB  1 
ATOM   5052 C CG  . PRO   D 4 75  ? 154.383 115.540 106.421 1.00 75.91  ? 75  PRO   E CG  1 
ATOM   5053 C CD  . PRO   D 4 75  ? 153.321 114.724 105.746 1.00 75.91  ? 75  PRO   E CD  1 
ATOM   5054 N N   . LYS   D 4 76  ? 155.549 114.801 102.612 1.00 74.15  ? 76  LYS   E N   1 
ATOM   5055 C CA  . LYS   D 4 76  ? 156.293 114.502 101.393 1.00 74.15  ? 76  LYS   E CA  1 
ATOM   5056 C C   . LYS   D 4 76  ? 155.394 114.156 100.210 1.00 74.15  ? 76  LYS   E C   1 
ATOM   5057 O O   . LYS   D 4 76  ? 155.915 113.909 99.116  1.00 74.15  ? 76  LYS   E O   1 
ATOM   5058 C CB  . LYS   D 4 76  ? 157.282 113.359 101.642 1.00 74.15  ? 76  LYS   E CB  1 
ATOM   5059 N N   . ASN   D 4 77  ? 154.073 114.131 100.402 1.00 68.51  ? 77  ASN   E N   1 
ATOM   5060 C CA  . ASN   D 4 77  ? 153.100 113.903 99.331  1.00 68.51  ? 77  ASN   E CA  1 
ATOM   5061 C C   . ASN   D 4 77  ? 153.330 112.560 98.637  1.00 68.51  ? 77  ASN   E C   1 
ATOM   5062 O O   . ASN   D 4 77  ? 153.642 112.490 97.449  1.00 68.51  ? 77  ASN   E O   1 
ATOM   5063 C CB  . ASN   D 4 77  ? 153.120 115.049 98.317  1.00 68.51  ? 77  ASN   E CB  1 
ATOM   5064 C CG  . ASN   D 4 77  ? 152.767 116.378 98.938  1.00 68.51  ? 77  ASN   E CG  1 
ATOM   5065 O OD1 . ASN   D 4 77  ? 151.703 116.534 99.530  1.00 68.51  ? 77  ASN   E OD1 1 
ATOM   5066 N ND2 . ASN   D 4 77  ? 153.657 117.352 98.799  1.00 68.51  ? 77  ASN   E ND2 1 
ATOM   5067 N N   . THR   D 4 78  ? 153.165 111.484 99.404  1.00 66.52  ? 78  THR   E N   1 
ATOM   5068 C CA  . THR   D 4 78  ? 153.379 110.144 98.881  1.00 66.52  ? 78  THR   E CA  1 
ATOM   5069 C C   . THR   D 4 78  ? 152.338 109.185 99.439  1.00 66.52  ? 78  THR   E C   1 
ATOM   5070 O O   . THR   D 4 78  ? 151.972 109.268 100.614 1.00 66.52  ? 78  THR   E O   1 
ATOM   5071 C CB  . THR   D 4 78  ? 154.787 109.641 99.212  1.00 66.52  ? 78  THR   E CB  1 
ATOM   5072 O OG1 . THR   D 4 78  ? 155.744 110.653 98.882  1.00 66.52  ? 78  THR   E OG1 1 
ATOM   5073 C CG2 . THR   D 4 78  ? 155.107 108.394 98.412  1.00 66.52  ? 78  THR   E CG2 1 
ATOM   5074 N N   . LEU   D 4 79  ? 151.868 108.281 98.585  1.00 63.22  ? 79  LEU   E N   1 
ATOM   5075 C CA  . LEU   D 4 79  ? 150.975 107.195 98.960  1.00 63.22  ? 79  LEU   E CA  1 
ATOM   5076 C C   . LEU   D 4 79  ? 151.739 105.880 98.988  1.00 63.22  ? 79  LEU   E C   1 
ATOM   5077 O O   . LEU   D 4 79  ? 152.544 105.604 98.096  1.00 63.22  ? 79  LEU   E O   1 
ATOM   5078 C CB  . LEU   D 4 79  ? 149.816 107.070 97.979  1.00 63.22  ? 79  LEU   E CB  1 
ATOM   5079 C CG  . LEU   D 4 79  ? 148.576 106.401 98.559  1.00 63.22  ? 79  LEU   E CG  1 
ATOM   5080 C CD1 . LEU   D 4 79  ? 148.174 107.057 99.857  1.00 63.22  ? 79  LEU   E CD1 1 
ATOM   5081 C CD2 . LEU   D 4 79  ? 147.450 106.367 97.563  1.00 63.22  ? 79  LEU   E CD2 1 
ATOM   5082 N N   . PHE   D 4 80  ? 151.479 105.063 100.003 1.00 63.31  ? 80  PHE   E N   1 
ATOM   5083 C CA  . PHE   D 4 80  ? 152.178 103.799 100.170 1.00 63.31  ? 80  PHE   E CA  1 
ATOM   5084 C C   . PHE   D 4 80  ? 151.188 102.649 100.250 1.00 63.31  ? 80  PHE   E C   1 
ATOM   5085 O O   . PHE   D 4 80  ? 150.151 102.752 100.911 1.00 63.31  ? 80  PHE   E O   1 
ATOM   5086 C CB  . PHE   D 4 80  ? 153.054 103.810 101.422 1.00 63.31  ? 80  PHE   E CB  1 
ATOM   5087 C CG  . PHE   D 4 80  ? 154.209 104.753 101.340 1.00 63.31  ? 80  PHE   E CG  1 
ATOM   5088 C CD1 . PHE   D 4 80  ? 155.215 104.560 100.416 1.00 63.31  ? 80  PHE   E CD1 1 
ATOM   5089 C CD2 . PHE   D 4 80  ? 154.292 105.830 102.194 1.00 63.31  ? 80  PHE   E CD2 1 
ATOM   5090 C CE1 . PHE   D 4 80  ? 156.277 105.429 100.341 1.00 63.31  ? 80  PHE   E CE1 1 
ATOM   5091 C CE2 . PHE   D 4 80  ? 155.349 106.698 102.125 1.00 63.31  ? 80  PHE   E CE2 1 
ATOM   5092 C CZ  . PHE   D 4 80  ? 156.344 106.499 101.197 1.00 63.31  ? 80  PHE   E CZ  1 
ATOM   5093 N N   . LEU   D 4 81  ? 151.510 101.558 99.561  1.00 63.67  ? 81  LEU   E N   1 
ATOM   5094 C CA  . LEU   D 4 81  ? 150.786 100.301 99.675  1.00 63.67  ? 81  LEU   E CA  1 
ATOM   5095 C C   . LEU   D 4 81  ? 151.784 99.222  100.052 1.00 63.67  ? 81  LEU   E C   1 
ATOM   5096 O O   . LEU   D 4 81  ? 152.807 99.059  99.381  1.00 63.67  ? 81  LEU   E O   1 
ATOM   5097 C CB  . LEU   D 4 81  ? 150.068 99.940  98.371  1.00 63.67  ? 81  LEU   E CB  1 
ATOM   5098 C CG  . LEU   D 4 81  ? 149.323 98.606  98.320  1.00 63.67  ? 81  LEU   E CG  1 
ATOM   5099 C CD1 . LEU   D 4 81  ? 147.932 98.739  98.881  1.00 63.67  ? 81  LEU   E CD1 1 
ATOM   5100 C CD2 . LEU   D 4 81  ? 149.260 98.101  96.903  1.00 63.67  ? 81  LEU   E CD2 1 
ATOM   5101 N N   . GLN   D 4 82  ? 151.490 98.493  101.119 1.00 67.98  ? 82  GLN   E N   1 
ATOM   5102 C CA  . GLN   D 4 82  ? 152.412 97.516  101.673 1.00 67.98  ? 82  GLN   E CA  1 
ATOM   5103 C C   . GLN   D 4 82  ? 151.922 96.115  101.348 1.00 67.98  ? 82  GLN   E C   1 
ATOM   5104 O O   . GLN   D 4 82  ? 150.729 95.827  101.467 1.00 67.98  ? 82  GLN   E O   1 
ATOM   5105 C CB  . GLN   D 4 82  ? 152.550 97.696  103.183 1.00 67.98  ? 82  GLN   E CB  1 
ATOM   5106 C CG  . GLN   D 4 82  ? 153.719 96.955  103.780 1.00 67.98  ? 82  GLN   E CG  1 
ATOM   5107 C CD  . GLN   D 4 82  ? 155.020 97.686  103.571 1.00 67.98  ? 82  GLN   E CD  1 
ATOM   5108 O OE1 . GLN   D 4 82  ? 155.138 98.866  103.897 1.00 67.98  ? 82  GLN   E OE1 1 
ATOM   5109 N NE2 . GLN   D 4 82  ? 156.008 96.991  103.023 1.00 67.98  ? 82  GLN   E NE2 1 
ATOM   5110 N N   . MET   D 4 83  ? 152.840 95.253  100.937 1.00 73.31  ? 83  MET   E N   1 
ATOM   5111 C CA  . MET   D 4 83  ? 152.515 93.899  100.523 1.00 73.31  ? 83  MET   E CA  1 
ATOM   5112 C C   . MET   D 4 83  ? 152.979 92.930  101.602 1.00 73.31  ? 83  MET   E C   1 
ATOM   5113 O O   . MET   D 4 83  ? 154.120 93.018  102.067 1.00 73.31  ? 83  MET   E O   1 
ATOM   5114 C CB  . MET   D 4 83  ? 153.200 93.569  99.197  1.00 73.31  ? 83  MET   E CB  1 
ATOM   5115 C CG  . MET   D 4 83  ? 153.027 94.636  98.130  1.00 73.31  ? 83  MET   E CG  1 
ATOM   5116 S SD  . MET   D 4 83  ? 151.341 94.883  97.577  1.00 73.31  ? 83  MET   E SD  1 
ATOM   5117 C CE  . MET   D 4 83  ? 151.618 95.470  95.918  1.00 73.31  ? 83  MET   E CE  1 
ATOM   5118 N N   . THR   D 4 84  ? 152.102 92.018  102.004 1.00 74.62  ? 84  THR   E N   1 
ATOM   5119 C CA  . THR   D 4 84  ? 152.462 90.992  102.973 1.00 74.62  ? 84  THR   E CA  1 
ATOM   5120 C C   . THR   D 4 84  ? 151.856 89.669  102.538 1.00 74.62  ? 84  THR   E C   1 
ATOM   5121 O O   . THR   D 4 84  ? 150.683 89.618  102.160 1.00 74.62  ? 84  THR   E O   1 
ATOM   5122 C CB  . THR   D 4 84  ? 151.982 91.359  104.382 1.00 74.62  ? 84  THR   E CB  1 
ATOM   5123 O OG1 . THR   D 4 84  ? 152.551 92.616  104.769 1.00 74.62  ? 84  THR   E OG1 1 
ATOM   5124 C CG2 . THR   D 4 84  ? 152.401 90.294  105.383 1.00 74.62  ? 84  THR   E CG2 1 
ATOM   5125 N N   . SER   D 4 85  ? 152.659 88.606  102.592 1.00 76.93  ? 85  SER   E N   1 
ATOM   5126 C CA  . SER   D 4 85  ? 152.240 87.264  102.191 1.00 76.93  ? 85  SER   E CA  1 
ATOM   5127 C C   . SER   D 4 85  ? 151.723 87.264  100.753 1.00 76.93  ? 85  SER   E C   1 
ATOM   5128 O O   . SER   D 4 85  ? 150.578 86.912  100.471 1.00 76.93  ? 85  SER   E O   1 
ATOM   5129 C CB  . SER   D 4 85  ? 151.192 86.704  103.159 1.00 76.93  ? 85  SER   E CB  1 
ATOM   5130 O OG  . SER   D 4 85  ? 150.567 85.552  102.621 1.00 76.93  ? 85  SER   E OG  1 
ATOM   5131 N N   . LEU   D 4 86  ? 152.599 87.674  99.842  1.00 75.88  ? 86  LEU   E N   1 
ATOM   5132 C CA  . LEU   D 4 86  ? 152.240 87.778  98.438  1.00 75.88  ? 86  LEU   E CA  1 
ATOM   5133 C C   . LEU   D 4 86  ? 151.960 86.407  97.840  1.00 75.88  ? 86  LEU   E C   1 
ATOM   5134 O O   . LEU   D 4 86  ? 152.552 85.397  98.229  1.00 75.88  ? 86  LEU   E O   1 
ATOM   5135 C CB  . LEU   D 4 86  ? 153.351 88.463  97.650  1.00 75.88  ? 86  LEU   E CB  1 
ATOM   5136 C CG  . LEU   D 4 86  ? 153.194 89.961  97.420  1.00 75.88  ? 86  LEU   E CG  1 
ATOM   5137 C CD1 . LEU   D 4 86  ? 154.278 90.458  96.489  1.00 75.88  ? 86  LEU   E CD1 1 
ATOM   5138 C CD2 . LEU   D 4 86  ? 151.821 90.279  96.865  1.00 75.88  ? 86  LEU   E CD2 1 
ATOM   5139 N N   . ARG   D 4 87  ? 151.043 86.381  96.880  1.00 75.74  ? 87  ARG   E N   1 
ATOM   5140 C CA  . ARG   D 4 87  ? 150.626 85.165  96.207  1.00 75.74  ? 87  ARG   E CA  1 
ATOM   5141 C C   . ARG   D 4 87  ? 150.567 85.426  94.710  1.00 75.74  ? 87  ARG   E C   1 
ATOM   5142 O O   . ARG   D 4 87  ? 150.650 86.569  94.253  1.00 75.74  ? 87  ARG   E O   1 
ATOM   5143 C CB  . ARG   D 4 87  ? 149.271 84.675  96.731  1.00 75.74  ? 87  ARG   E CB  1 
ATOM   5144 C CG  . ARG   D 4 87  ? 148.125 85.614  96.435  1.00 75.74  ? 87  ARG   E CG  1 
ATOM   5145 C CD  . ARG   D 4 87  ? 146.803 85.065  96.942  1.00 75.74  ? 87  ARG   E CD  1 
ATOM   5146 N NE  . ARG   D 4 87  ? 146.687 85.157  98.393  1.00 75.74  ? 87  ARG   E NE  1 
ATOM   5147 C CZ  . ARG   D 4 87  ? 145.656 84.690  99.088  1.00 75.74  ? 87  ARG   E CZ  1 
ATOM   5148 N NH1 . ARG   D 4 87  ? 144.649 84.098  98.463  1.00 75.74  ? 87  ARG   E NH1 1 
ATOM   5149 N NH2 . ARG   D 4 87  ? 145.631 84.815  100.407 1.00 75.74  ? 87  ARG   E NH2 1 
ATOM   5150 N N   . SER   D 4 88  ? 150.425 84.348  93.939  1.00 76.73  ? 88  SER   E N   1 
ATOM   5151 C CA  . SER   D 4 88  ? 150.478 84.442  92.484  1.00 76.73  ? 88  SER   E CA  1 
ATOM   5152 C C   . SER   D 4 88  ? 149.285 85.175  91.884  1.00 76.73  ? 88  SER   E C   1 
ATOM   5153 O O   . SER   D 4 88  ? 149.322 85.501  90.694  1.00 76.73  ? 88  SER   E O   1 
ATOM   5154 C CB  . SER   D 4 88  ? 150.576 83.045  91.873  1.00 76.73  ? 88  SER   E CB  1 
ATOM   5155 O OG  . SER   D 4 88  ? 150.478 83.102  90.461  1.00 76.73  ? 88  SER   E OG  1 
ATOM   5156 N N   . GLU   D 4 89  ? 148.241 85.437  92.663  1.00 74.91  ? 89  GLU   E N   1 
ATOM   5157 C CA  . GLU   D 4 89  ? 147.061 86.138  92.180  1.00 74.91  ? 89  GLU   E CA  1 
ATOM   5158 C C   . GLU   D 4 89  ? 147.183 87.651  92.294  1.00 74.91  ? 89  GLU   E C   1 
ATOM   5159 O O   . GLU   D 4 89  ? 146.215 88.359  92.001  1.00 74.91  ? 89  GLU   E O   1 
ATOM   5160 C CB  . GLU   D 4 89  ? 145.820 85.665  92.941  1.00 74.91  ? 89  GLU   E CB  1 
ATOM   5161 N N   . ASP   D 4 90  ? 148.339 88.161  92.711  1.00 71.15  ? 90  ASP   E N   1 
ATOM   5162 C CA  . ASP   D 4 90  ? 148.553 89.587  92.889  1.00 71.15  ? 90  ASP   E CA  1 
ATOM   5163 C C   . ASP   D 4 90  ? 149.389 90.205  91.778  1.00 71.15  ? 90  ASP   E C   1 
ATOM   5164 O O   . ASP   D 4 90  ? 149.852 91.338  91.926  1.00 71.15  ? 90  ASP   E O   1 
ATOM   5165 C CB  . ASP   D 4 90  ? 149.205 89.850  94.243  1.00 71.15  ? 90  ASP   E CB  1 
ATOM   5166 C CG  . ASP   D 4 90  ? 148.271 89.579  95.396  1.00 71.15  ? 90  ASP   E CG  1 
ATOM   5167 O OD1 . ASP   D 4 90  ? 147.052 89.772  95.226  1.00 71.15  ? 90  ASP   E OD1 1 
ATOM   5168 O OD2 . ASP   D 4 90  ? 148.749 89.172  96.472  1.00 71.15  ? 90  ASP   E OD2 1 
ATOM   5169 N N   . THR   D 4 91  ? 149.600 89.491  90.676  1.00 68.74  ? 91  THR   E N   1 
ATOM   5170 C CA  . THR   D 4 91  ? 150.291 90.053  89.523  1.00 68.74  ? 91  THR   E CA  1 
ATOM   5171 C C   . THR   D 4 91  ? 149.327 90.949  88.763  1.00 68.74  ? 91  THR   E C   1 
ATOM   5172 O O   . THR   D 4 91  ? 148.268 90.489  88.322  1.00 68.74  ? 91  THR   E O   1 
ATOM   5173 C CB  . THR   D 4 91  ? 150.819 88.947  88.615  1.00 68.74  ? 91  THR   E CB  1 
ATOM   5174 N N   . ALA   D 4 92  ? 149.683 92.214  88.603  1.00 64.21  ? 92  ALA   E N   1 
ATOM   5175 C CA  . ALA   D 4 92  ? 148.793 93.184  87.976  1.00 64.21  ? 92  ALA   E CA  1 
ATOM   5176 C C   . ALA   D 4 92  ? 149.600 94.426  87.629  1.00 64.21  ? 92  ALA   E C   1 
ATOM   5177 O O   . ALA   D 4 92  ? 150.823 94.463  87.804  1.00 64.21  ? 92  ALA   E O   1 
ATOM   5178 C CB  . ALA   D 4 92  ? 147.614 93.515  88.890  1.00 64.21  ? 92  ALA   E CB  1 
ATOM   5179 N N   . MET   D 4 93  ? 148.909 95.440  87.120  1.00 63.12  ? 93  MET   E N   1 
ATOM   5180 C CA  . MET   D 4 93  ? 149.434 96.791  86.978  1.00 63.12  ? 93  MET   E CA  1 
ATOM   5181 C C   . MET   D 4 93  ? 148.657 97.680  87.934  1.00 63.12  ? 93  MET   E C   1 
ATOM   5182 O O   . MET   D 4 93  ? 147.434 97.795  87.816  1.00 63.12  ? 93  MET   E O   1 
ATOM   5183 C CB  . MET   D 4 93  ? 149.296 97.287  85.540  1.00 63.12  ? 93  MET   E CB  1 
ATOM   5184 C CG  . MET   D 4 93  ? 149.924 98.631  85.288  1.00 63.12  ? 93  MET   E CG  1 
ATOM   5185 S SD  . MET   D 4 93  ? 149.747 99.170  83.577  1.00 63.12  ? 93  MET   E SD  1 
ATOM   5186 C CE  . MET   D 4 93  ? 150.889 98.064  82.753  1.00 63.12  ? 93  MET   E CE  1 
ATOM   5187 N N   . TYR   D 4 94  ? 149.356 98.305  88.873  1.00 58.91  ? 94  TYR   E N   1 
ATOM   5188 C CA  . TYR   D 4 94  ? 148.700 98.995  89.973  1.00 58.91  ? 94  TYR   E CA  1 
ATOM   5189 C C   . TYR   D 4 94  ? 148.533 100.472 89.657  1.00 58.91  ? 94  TYR   E C   1 
ATOM   5190 O O   . TYR   D 4 94  ? 149.494 101.147 89.280  1.00 58.91  ? 94  TYR   E O   1 
ATOM   5191 C CB  . TYR   D 4 94  ? 149.487 98.804  91.265  1.00 58.91  ? 94  TYR   E CB  1 
ATOM   5192 C CG  . TYR   D 4 94  ? 149.245 97.460  91.890  1.00 58.91  ? 94  TYR   E CG  1 
ATOM   5193 C CD1 . TYR   D 4 94  ? 149.788 96.317  91.340  1.00 58.91  ? 94  TYR   E CD1 1 
ATOM   5194 C CD2 . TYR   D 4 94  ? 148.462 97.332  93.014  1.00 58.91  ? 94  TYR   E CD2 1 
ATOM   5195 C CE1 . TYR   D 4 94  ? 149.568 95.090  91.896  1.00 58.91  ? 94  TYR   E CE1 1 
ATOM   5196 C CE2 . TYR   D 4 94  ? 148.234 96.108  93.571  1.00 58.91  ? 94  TYR   E CE2 1 
ATOM   5197 C CZ  . TYR   D 4 94  ? 148.789 94.989  93.005  1.00 58.91  ? 94  TYR   E CZ  1 
ATOM   5198 O OH  . TYR   D 4 94  ? 148.574 93.757  93.556  1.00 58.91  ? 94  TYR   E OH  1 
ATOM   5199 N N   . TYR   D 4 95  ? 147.309 100.966 89.812  1.00 56.13  ? 95  TYR   E N   1 
ATOM   5200 C CA  . TYR   D 4 95  ? 146.953 102.329 89.465  1.00 56.13  ? 95  TYR   E CA  1 
ATOM   5201 C C   . TYR   D 4 95  ? 146.618 103.119 90.718  1.00 56.13  ? 95  TYR   E C   1 
ATOM   5202 O O   . TYR   D 4 95  ? 145.992 102.601 91.644  1.00 56.13  ? 95  TYR   E O   1 
ATOM   5203 C CB  . TYR   D 4 95  ? 145.767 102.363 88.503  1.00 56.13  ? 95  TYR   E CB  1 
ATOM   5204 C CG  . TYR   D 4 95  ? 146.121 101.962 87.105  1.00 56.13  ? 95  TYR   E CG  1 
ATOM   5205 C CD1 . TYR   D 4 95  ? 147.081 102.650 86.394  1.00 56.13  ? 95  TYR   E CD1 1 
ATOM   5206 C CD2 . TYR   D 4 95  ? 145.517 100.882 86.503  1.00 56.13  ? 95  TYR   E CD2 1 
ATOM   5207 C CE1 . TYR   D 4 95  ? 147.421 102.276 85.123  1.00 56.13  ? 95  TYR   E CE1 1 
ATOM   5208 C CE2 . TYR   D 4 95  ? 145.852 100.503 85.236  1.00 56.13  ? 95  TYR   E CE2 1 
ATOM   5209 C CZ  . TYR   D 4 95  ? 146.805 101.202 84.549  1.00 56.13  ? 95  TYR   E CZ  1 
ATOM   5210 O OH  . TYR   D 4 95  ? 147.138 100.824 83.272  1.00 56.13  ? 95  TYR   E OH  1 
ATOM   5211 N N   . CYS   D 4 96  ? 147.045 104.372 90.735  1.00 55.77  ? 96  CYS   E N   1 
ATOM   5212 C CA  . CYS   D 4 96  ? 146.823 105.296 91.834  1.00 55.77  ? 96  CYS   E CA  1 
ATOM   5213 C C   . CYS   D 4 96  ? 145.837 106.346 91.355  1.00 55.77  ? 96  CYS   E C   1 
ATOM   5214 O O   . CYS   D 4 96  ? 146.086 107.019 90.351  1.00 55.77  ? 96  CYS   E O   1 
ATOM   5215 C CB  . CYS   D 4 96  ? 148.147 105.933 92.260  1.00 55.77  ? 96  CYS   E CB  1 
ATOM   5216 S SG  . CYS   D 4 96  ? 148.192 106.868 93.798  1.00 55.77  ? 96  CYS   E SG  1 
ATOM   5217 N N   . VAL   D 4 97  ? 144.725 106.480 92.057  1.00 48.52  ? 97  VAL   E N   1 
ATOM   5218 C CA  . VAL   D 4 97  ? 143.624 107.323 91.620  1.00 48.52  ? 97  VAL   E CA  1 
ATOM   5219 C C   . VAL   D 4 97  ? 143.323 108.325 92.718  1.00 48.52  ? 97  VAL   E C   1 
ATOM   5220 O O   . VAL   D 4 97  ? 143.414 108.007 93.905  1.00 48.52  ? 97  VAL   E O   1 
ATOM   5221 C CB  . VAL   D 4 97  ? 142.376 106.480 91.298  1.00 48.52  ? 97  VAL   E CB  1 
ATOM   5222 C CG1 . VAL   D 4 97  ? 141.216 107.362 90.906  1.00 48.52  ? 97  VAL   E CG1 1 
ATOM   5223 C CG2 . VAL   D 4 97  ? 142.682 105.479 90.225  1.00 48.52  ? 97  VAL   E CG2 1 
ATOM   5224 N N   . ARG   D 4 98  ? 142.968 109.540 92.329  1.00 51.86  ? 98  ARG   E N   1 
ATOM   5225 C CA  . ARG   D 4 98  ? 142.549 110.553 93.280  1.00 51.86  ? 98  ARG   E CA  1 
ATOM   5226 C C   . ARG   D 4 98  ? 141.064 110.834 93.122  1.00 51.86  ? 98  ARG   E C   1 
ATOM   5227 O O   . ARG   D 4 98  ? 140.519 110.788 92.017  1.00 51.86  ? 98  ARG   E O   1 
ATOM   5228 C CB  . ARG   D 4 98  ? 143.340 111.852 93.113  1.00 51.86  ? 98  ARG   E CB  1 
ATOM   5229 C CG  . ARG   D 4 98  ? 143.068 112.636 91.854  1.00 51.86  ? 98  ARG   E CG  1 
ATOM   5230 C CD  . ARG   D 4 98  ? 143.640 114.026 92.002  1.00 51.86  ? 98  ARG   E CD  1 
ATOM   5231 N NE  . ARG   D 4 98  ? 143.570 114.825 90.784  1.00 51.86  ? 98  ARG   E NE  1 
ATOM   5232 C CZ  . ARG   D 4 98  ? 142.534 115.580 90.438  1.00 51.86  ? 98  ARG   E CZ  1 
ATOM   5233 N NH1 . ARG   D 4 98  ? 141.462 115.633 91.208  1.00 51.86  ? 98  ARG   E NH1 1 
ATOM   5234 N NH2 . ARG   D 4 98  ? 142.564 116.273 89.314  1.00 51.86  ? 98  ARG   E NH2 1 
ATOM   5235 N N   . SER   D 4 99  ? 140.408 111.112 94.239  1.00 50.98  ? 99  SER   E N   1 
ATOM   5236 C CA  . SER   D 4 99  ? 138.979 111.364 94.223  1.00 50.98  ? 99  SER   E CA  1 
ATOM   5237 C C   . SER   D 4 99  ? 138.627 112.337 95.332  1.00 50.98  ? 99  SER   E C   1 
ATOM   5238 O O   . SER   D 4 99  ? 139.060 112.163 96.472  1.00 50.98  ? 99  SER   E O   1 
ATOM   5239 C CB  . SER   D 4 99  ? 138.195 110.061 94.391  1.00 50.98  ? 99  SER   E CB  1 
ATOM   5240 O OG  . SER   D 4 99  ? 138.222 109.625 95.734  1.00 50.98  ? 99  SER   E OG  1 
ATOM   5241 N N   . ILE   D 4 100 ? 137.842 113.353 94.996  1.00 52.95  ? 100 ILE   E N   1 
ATOM   5242 C CA  . ILE   D 4 100 ? 137.333 114.315 95.960  1.00 52.95  ? 100 ILE   E CA  1 
ATOM   5243 C C   . ILE   D 4 100 ? 135.821 114.175 96.012  1.00 52.95  ? 100 ILE   E C   1 
ATOM   5244 O O   . ILE   D 4 100 ? 135.186 113.854 95.004  1.00 52.95  ? 100 ILE   E O   1 
ATOM   5245 C CB  . ILE   D 4 100 ? 137.762 115.753 95.608  1.00 52.95  ? 100 ILE   E CB  1 
ATOM   5246 C CG1 . ILE   D 4 100 ? 137.645 116.650 96.834  1.00 52.95  ? 100 ILE   E CG1 1 
ATOM   5247 C CG2 . ILE   D 4 100 ? 136.963 116.296 94.443  1.00 52.95  ? 100 ILE   E CG2 1 
ATOM   5248 C CD1 . ILE   D 4 100 ? 138.522 117.872 96.771  1.00 52.95  ? 100 ILE   E CD1 1 
ATOM   5249 N N   . TYR   D 4 101 ? 135.250 114.363 97.199  1.00 51.73  ? 101 TYR   E N   1 
ATOM   5250 C CA  . TYR   D 4 101 ? 133.840 114.084 97.446  1.00 51.73  ? 101 TYR   E CA  1 
ATOM   5251 C C   . TYR   D 4 101 ? 133.166 115.314 98.035  1.00 51.73  ? 101 TYR   E C   1 
ATOM   5252 O O   . TYR   D 4 101 ? 133.483 115.723 99.154  1.00 51.73  ? 101 TYR   E O   1 
ATOM   5253 C CB  . TYR   D 4 101 ? 133.678 112.889 98.379  1.00 51.73  ? 101 TYR   E CB  1 
ATOM   5254 C CG  . TYR   D 4 101 ? 134.170 111.580 97.816  1.00 51.73  ? 101 TYR   E CG  1 
ATOM   5255 C CD1 . TYR   D 4 101 ? 133.460 110.910 96.844  1.00 51.73  ? 101 TYR   E CD1 1 
ATOM   5256 C CD2 . TYR   D 4 101 ? 135.342 111.016 98.265  1.00 51.73  ? 101 TYR   E CD2 1 
ATOM   5257 C CE1 . TYR   D 4 101 ? 133.910 109.721 96.336  1.00 51.73  ? 101 TYR   E CE1 1 
ATOM   5258 C CE2 . TYR   D 4 101 ? 135.795 109.829 97.763  1.00 51.73  ? 101 TYR   E CE2 1 
ATOM   5259 C CZ  . TYR   D 4 101 ? 135.079 109.185 96.800  1.00 51.73  ? 101 TYR   E CZ  1 
ATOM   5260 O OH  . TYR   D 4 101 ? 135.535 107.995 96.295  1.00 51.73  ? 101 TYR   E OH  1 
ATOM   5261 N N   . TYR   D 4 102 ? 132.245 115.897 97.280  1.00 51.50  ? 102 TYR   E N   1 
ATOM   5262 C CA  . TYR   D 4 102 ? 131.351 116.952 97.746  1.00 51.50  ? 102 TYR   E CA  1 
ATOM   5263 C C   . TYR   D 4 102 ? 130.296 117.154 96.669  1.00 51.50  ? 102 TYR   E C   1 
ATOM   5264 O O   . TYR   D 4 102 ? 130.307 116.488 95.630  1.00 51.50  ? 102 TYR   E O   1 
ATOM   5265 C CB  . TYR   D 4 102 ? 132.090 118.254 98.065  1.00 51.50  ? 102 TYR   E CB  1 
ATOM   5266 C CG  . TYR   D 4 102 ? 132.999 118.780 96.983  1.00 51.50  ? 102 TYR   E CG  1 
ATOM   5267 C CD1 . TYR   D 4 102 ? 132.542 119.674 96.038  1.00 51.50  ? 102 TYR   E CD1 1 
ATOM   5268 C CD2 . TYR   D 4 102 ? 134.316 118.397 96.921  1.00 51.50  ? 102 TYR   E CD2 1 
ATOM   5269 C CE1 . TYR   D 4 102 ? 133.368 120.156 95.063  1.00 51.50  ? 102 TYR   E CE1 1 
ATOM   5270 C CE2 . TYR   D 4 102 ? 135.146 118.873 95.947  1.00 51.50  ? 102 TYR   E CE2 1 
ATOM   5271 C CZ  . TYR   D 4 102 ? 134.669 119.750 95.022  1.00 51.50  ? 102 TYR   E CZ  1 
ATOM   5272 O OH  . TYR   D 4 102 ? 135.506 120.230 94.046  1.00 51.50  ? 102 TYR   E OH  1 
ATOM   5273 N N   . TYR   D 4 103 ? 129.372 118.066 96.932  1.00 55.48  ? 103 TYR   E N   1 
ATOM   5274 C CA  . TYR   D 4 103 ? 128.392 118.449 95.928  1.00 55.48  ? 103 TYR   E CA  1 
ATOM   5275 C C   . TYR   D 4 103 ? 129.068 119.019 94.695  1.00 55.48  ? 103 TYR   E C   1 
ATOM   5276 O O   . TYR   D 4 103 ? 129.750 120.044 94.767  1.00 55.48  ? 103 TYR   E O   1 
ATOM   5277 C CB  . TYR   D 4 103 ? 127.418 119.466 96.509  1.00 55.48  ? 103 TYR   E CB  1 
ATOM   5278 C CG  . TYR   D 4 103 ? 126.170 119.599 95.687  1.00 55.48  ? 103 TYR   E CG  1 
ATOM   5279 C CD1 . TYR   D 4 103 ? 126.022 120.643 94.789  1.00 55.48  ? 103 TYR   E CD1 1 
ATOM   5280 C CD2 . TYR   D 4 103 ? 125.173 118.657 95.757  1.00 55.48  ? 103 TYR   E CD2 1 
ATOM   5281 C CE1 . TYR   D 4 103 ? 124.890 120.760 94.017  1.00 55.48  ? 103 TYR   E CE1 1 
ATOM   5282 C CE2 . TYR   D 4 103 ? 124.046 118.764 94.985  1.00 55.48  ? 103 TYR   E CE2 1 
ATOM   5283 C CZ  . TYR   D 4 103 ? 123.904 119.814 94.122  1.00 55.48  ? 103 TYR   E CZ  1 
ATOM   5284 O OH  . TYR   D 4 103 ? 122.763 119.908 93.358  1.00 55.48  ? 103 TYR   E OH  1 
ATOM   5285 N N   . GLY   D 4 104 ? 128.854 118.369 93.557  1.00 54.91  ? 104 GLY   E N   1 
ATOM   5286 C CA  . GLY   D 4 104 ? 129.442 118.796 92.312  1.00 54.91  ? 104 GLY   E CA  1 
ATOM   5287 C C   . GLY   D 4 104 ? 130.761 118.143 91.992  1.00 54.91  ? 104 GLY   E C   1 
ATOM   5288 O O   . GLY   D 4 104 ? 131.363 118.469 90.963  1.00 54.91  ? 104 GLY   E O   1 
ATOM   5289 N N   . SER   D 4 105 ? 131.226 117.232 92.835  1.00 55.20  ? 105 SER   E N   1 
ATOM   5290 C CA  . SER   D 4 105 ? 132.522 116.620 92.643  1.00 55.20  ? 105 SER   E CA  1 
ATOM   5291 C C   . SER   D 4 105 ? 132.492 115.643 91.480  1.00 55.20  ? 105 SER   E C   1 
ATOM   5292 O O   . SER   D 4 105 ? 131.436 115.216 91.009  1.00 55.20  ? 105 SER   E O   1 
ATOM   5293 C CB  . SER   D 4 105 ? 132.963 115.899 93.906  1.00 55.20  ? 105 SER   E CB  1 
ATOM   5294 O OG  . SER   D 4 105 ? 133.989 114.971 93.615  1.00 55.20  ? 105 SER   E OG  1 
ATOM   5295 N N   . SER   D 4 106 ? 133.683 115.297 91.017  1.00 55.43  ? 106 SER   E N   1 
ATOM   5296 C CA  . SER   D 4 106 ? 133.877 114.336 89.940  1.00 55.43  ? 106 SER   E CA  1 
ATOM   5297 C C   . SER   D 4 106 ? 134.920 113.329 90.391  1.00 55.43  ? 106 SER   E C   1 
ATOM   5298 O O   . SER   D 4 106 ? 136.071 113.371 89.950  1.00 55.43  ? 106 SER   E O   1 
ATOM   5299 C CB  . SER   D 4 106 ? 134.305 115.044 88.656  1.00 55.43  ? 106 SER   E CB  1 
ATOM   5300 O OG  . SER   D 4 106 ? 135.437 115.859 88.887  1.00 55.43  ? 106 SER   E OG  1 
ATOM   5301 N N   . PRO   D 4 107 ? 134.557 112.417 91.286  1.00 55.92  ? 107 PRO   E N   1 
ATOM   5302 C CA  . PRO   D 4 107 ? 135.534 111.443 91.770  1.00 55.92  ? 107 PRO   E CA  1 
ATOM   5303 C C   . PRO   D 4 107 ? 136.066 110.578 90.640  1.00 55.92  ? 107 PRO   E C   1 
ATOM   5304 O O   . PRO   D 4 107 ? 135.405 110.355 89.623  1.00 55.92  ? 107 PRO   E O   1 
ATOM   5305 C CB  . PRO   D 4 107 ? 134.745 110.617 92.790  1.00 55.92  ? 107 PRO   E CB  1 
ATOM   5306 C CG  . PRO   D 4 107 ? 133.339 110.891 92.514  1.00 55.92  ? 107 PRO   E CG  1 
ATOM   5307 C CD  . PRO   D 4 107 ? 133.256 112.260 91.947  1.00 55.92  ? 107 PRO   E CD  1 
ATOM   5308 N N   . PHE   D 4 108 ? 137.304 110.120 90.829  1.00 54.81  ? 108 PHE   E N   1 
ATOM   5309 C CA  . PHE   D 4 108 ? 138.039 109.343 89.833  1.00 54.81  ? 108 PHE   E CA  1 
ATOM   5310 C C   . PHE   D 4 108 ? 138.364 110.182 88.605  1.00 54.81  ? 108 PHE   E C   1 
ATOM   5311 O O   . PHE   D 4 108 ? 138.233 109.727 87.469  1.00 54.81  ? 108 PHE   E O   1 
ATOM   5312 C CB  . PHE   D 4 108 ? 137.280 108.078 89.445  1.00 54.81  ? 108 PHE   E CB  1 
ATOM   5313 C CG  . PHE   D 4 108 ? 137.258 107.041 90.515  1.00 54.81  ? 108 PHE   E CG  1 
ATOM   5314 C CD1 . PHE   D 4 108 ? 138.103 105.949 90.459  1.00 54.81  ? 108 PHE   E CD1 1 
ATOM   5315 C CD2 . PHE   D 4 108 ? 136.393 107.155 91.578  1.00 54.81  ? 108 PHE   E CD2 1 
ATOM   5316 C CE1 . PHE   D 4 108 ? 138.083 104.997 91.446  1.00 54.81  ? 108 PHE   E CE1 1 
ATOM   5317 C CE2 . PHE   D 4 108 ? 136.370 106.211 92.558  1.00 54.81  ? 108 PHE   E CE2 1 
ATOM   5318 C CZ  . PHE   D 4 108 ? 137.215 105.129 92.494  1.00 54.81  ? 108 PHE   E CZ  1 
ATOM   5319 N N   . ASP   D 4 109 ? 138.800 111.420 88.831  1.00 57.21  ? 109 ASP   E N   1 
ATOM   5320 C CA  . ASP   D 4 109 ? 139.230 112.265 87.725  1.00 57.21  ? 109 ASP   E CA  1 
ATOM   5321 C C   . ASP   D 4 109 ? 140.557 111.793 87.151  1.00 57.21  ? 109 ASP   E C   1 
ATOM   5322 O O   . ASP   D 4 109 ? 140.639 111.402 85.982  1.00 57.21  ? 109 ASP   E O   1 
ATOM   5323 C CB  . ASP   D 4 109 ? 139.338 113.722 88.174  1.00 57.21  ? 109 ASP   E CB  1 
ATOM   5324 C CG  . ASP   D 4 109 ? 138.011 114.438 88.156  1.00 57.21  ? 109 ASP   E CG  1 
ATOM   5325 O OD1 . ASP   D 4 109 ? 137.153 114.081 87.321  1.00 57.21  ? 109 ASP   E OD1 1 
ATOM   5326 O OD2 . ASP   D 4 109 ? 137.824 115.365 88.971  1.00 57.21  ? 109 ASP   E OD2 1 
ATOM   5327 N N   . PHE   D 4 110 ? 141.611 111.818 87.960  1.00 57.57  ? 110 PHE   E N   1 
ATOM   5328 C CA  . PHE   D 4 110 ? 142.957 111.551 87.482  1.00 57.57  ? 110 PHE   E CA  1 
ATOM   5329 C C   . PHE   D 4 110 ? 143.440 110.196 87.969  1.00 57.57  ? 110 PHE   E C   1 
ATOM   5330 O O   . PHE   D 4 110 ? 143.359 109.889 89.161  1.00 57.57  ? 110 PHE   E O   1 
ATOM   5331 C CB  . PHE   D 4 110 ? 143.930 112.642 87.922  1.00 57.57  ? 110 PHE   E CB  1 
ATOM   5332 C CG  . PHE   D 4 110 ? 145.207 112.649 87.144  1.00 57.57  ? 110 PHE   E CG  1 
ATOM   5333 C CD1 . PHE   D 4 110 ? 146.218 111.759 87.438  1.00 57.57  ? 110 PHE   E CD1 1 
ATOM   5334 C CD2 . PHE   D 4 110 ? 145.381 113.520 86.093  1.00 57.57  ? 110 PHE   E CD2 1 
ATOM   5335 C CE1 . PHE   D 4 110 ? 147.387 111.757 86.713  1.00 57.57  ? 110 PHE   E CE1 1 
ATOM   5336 C CE2 . PHE   D 4 110 ? 146.546 113.520 85.364  1.00 57.57  ? 110 PHE   E CE2 1 
ATOM   5337 C CZ  . PHE   D 4 110 ? 147.548 112.640 85.674  1.00 57.57  ? 110 PHE   E CZ  1 
ATOM   5338 N N   . TRP   D 4 111 ? 143.943 109.400 87.037  1.00 53.07  ? 111 TRP   E N   1 
ATOM   5339 C CA  . TRP   D 4 111 ? 144.581 108.129 87.318  1.00 53.07  ? 111 TRP   E CA  1 
ATOM   5340 C C   . TRP   D 4 111 ? 146.054 108.240 86.974  1.00 53.07  ? 111 TRP   E C   1 
ATOM   5341 O O   . TRP   D 4 111 ? 146.419 108.842 85.962  1.00 53.07  ? 111 TRP   E O   1 
ATOM   5342 C CB  . TRP   D 4 111 ? 143.968 106.993 86.501  1.00 53.07  ? 111 TRP   E CB  1 
ATOM   5343 C CG  . TRP   D 4 111 ? 142.546 106.661 86.769  1.00 53.07  ? 111 TRP   E CG  1 
ATOM   5344 C CD1 . TRP   D 4 111 ? 141.510 107.525 86.868  1.00 53.07  ? 111 TRP   E CD1 1 
ATOM   5345 C CD2 . TRP   D 4 111 ? 141.997 105.356 86.931  1.00 53.07  ? 111 TRP   E CD2 1 
ATOM   5346 N NE1 . TRP   D 4 111 ? 140.350 106.844 87.101  1.00 53.07  ? 111 TRP   E NE1 1 
ATOM   5347 C CE2 . TRP   D 4 111 ? 140.625 105.506 87.137  1.00 53.07  ? 111 TRP   E CE2 1 
ATOM   5348 C CE3 . TRP   D 4 111 ? 142.539 104.073 86.933  1.00 53.07  ? 111 TRP   E CE3 1 
ATOM   5349 C CZ2 . TRP   D 4 111 ? 139.787 104.429 87.345  1.00 53.07  ? 111 TRP   E CZ2 1 
ATOM   5350 C CZ3 . TRP   D 4 111 ? 141.708 103.011 87.128  1.00 53.07  ? 111 TRP   E CZ3 1 
ATOM   5351 C CH2 . TRP   D 4 111 ? 140.348 103.191 87.334  1.00 53.07  ? 111 TRP   E CH2 1 
ATOM   5352 N N   . GLY   D 4 112 ? 146.896 107.643 87.797  1.00 57.68  ? 112 GLY   E N   1 
ATOM   5353 C CA  . GLY   D 4 112 ? 148.310 107.619 87.526  1.00 57.68  ? 112 GLY   E CA  1 
ATOM   5354 C C   . GLY   D 4 112 ? 148.673 106.530 86.545  1.00 57.68  ? 112 GLY   E C   1 
ATOM   5355 O O   . GLY   D 4 112 ? 147.826 105.831 85.990  1.00 57.68  ? 112 GLY   E O   1 
ATOM   5356 N N   . GLN   D 4 113 ? 149.971 106.392 86.333  1.00 64.83  ? 113 GLN   E N   1 
ATOM   5357 C CA  . GLN   D 4 113 ? 150.503 105.313 85.517  1.00 64.83  ? 113 GLN   E CA  1 
ATOM   5358 C C   . GLN   D 4 113 ? 150.507 104.038 86.355  1.00 64.83  ? 113 GLN   E C   1 
ATOM   5359 O O   . GLN   D 4 113 ? 149.871 103.957 87.408  1.00 64.83  ? 113 GLN   E O   1 
ATOM   5360 C CB  . GLN   D 4 113 ? 151.887 105.679 84.996  1.00 64.83  ? 113 GLN   E CB  1 
ATOM   5361 C CG  . GLN   D 4 113 ? 151.903 106.918 84.126  1.00 64.83  ? 113 GLN   E CG  1 
ATOM   5362 C CD  . GLN   D 4 113 ? 151.144 106.725 82.830  1.00 64.83  ? 113 GLN   E CD  1 
ATOM   5363 O OE1 . GLN   D 4 113 ? 150.134 107.384 82.585  1.00 64.83  ? 113 GLN   E OE1 1 
ATOM   5364 N NE2 . GLN   D 4 113 ? 151.625 105.815 81.992  1.00 64.83  ? 113 GLN   E NE2 1 
ATOM   5365 N N   . GLY   D 4 114 ? 151.211 103.014 85.897  1.00 65.54  ? 114 GLY   E N   1 
ATOM   5366 C CA  . GLY   D 4 114 ? 151.176 101.760 86.613  1.00 65.54  ? 114 GLY   E CA  1 
ATOM   5367 C C   . GLY   D 4 114 ? 152.530 101.221 87.011  1.00 65.54  ? 114 GLY   E C   1 
ATOM   5368 O O   . GLY   D 4 114 ? 153.556 101.592 86.435  1.00 65.54  ? 114 GLY   E O   1 
ATOM   5369 N N   . THR   D 4 115 ? 152.538 100.343 88.003  1.00 68.87  ? 115 THR   E N   1 
ATOM   5370 C CA  . THR   D 4 115 ? 153.736 99.632  88.429  1.00 68.87  ? 115 THR   E CA  1 
ATOM   5371 C C   . THR   D 4 115 ? 153.477 98.146  88.234  1.00 68.87  ? 115 THR   E C   1 
ATOM   5372 O O   . THR   D 4 115 ? 152.810 97.514  89.057  1.00 68.87  ? 115 THR   E O   1 
ATOM   5373 C CB  . THR   D 4 115 ? 154.082 99.945  89.878  1.00 68.87  ? 115 THR   E CB  1 
ATOM   5374 O OG1 . THR   D 4 115 ? 152.976 99.600  90.721  1.00 68.87  ? 115 THR   E OG1 1 
ATOM   5375 C CG2 . THR   D 4 115 ? 154.413 101.409 90.040  1.00 68.87  ? 115 THR   E CG2 1 
ATOM   5376 N N   . THR   D 4 116 ? 154.007 97.593  87.148  1.00 72.99  ? 116 THR   E N   1 
ATOM   5377 C CA  . THR   D 4 116 ? 153.837 96.178  86.861  1.00 72.99  ? 116 THR   E CA  1 
ATOM   5378 C C   . THR   D 4 116 ? 154.463 95.334  87.960  1.00 72.99  ? 116 THR   E C   1 
ATOM   5379 O O   . THR   D 4 116 ? 155.687 95.318  88.117  1.00 72.99  ? 116 THR   E O   1 
ATOM   5380 C CB  . THR   D 4 116 ? 154.453 95.826  85.509  1.00 72.99  ? 116 THR   E CB  1 
ATOM   5381 O OG1 . THR   D 4 116 ? 153.745 96.510  84.468  1.00 72.99  ? 116 THR   E OG1 1 
ATOM   5382 C CG2 . THR   D 4 116 ? 154.372 94.329  85.265  1.00 72.99  ? 116 THR   E CG2 1 
ATOM   5383 N N   . LEU   D 4 117 ? 153.635 94.634  88.724  1.00 72.57  ? 117 LEU   E N   1 
ATOM   5384 C CA  . LEU   D 4 117 ? 154.099 93.736  89.768  1.00 72.57  ? 117 LEU   E CA  1 
ATOM   5385 C C   . LEU   D 4 117 ? 153.880 92.299  89.321  1.00 72.57  ? 117 LEU   E C   1 
ATOM   5386 O O   . LEU   D 4 117 ? 152.787 91.946  88.867  1.00 72.57  ? 117 LEU   E O   1 
ATOM   5387 C CB  . LEU   D 4 117 ? 153.380 94.014  91.088  1.00 72.57  ? 117 LEU   E CB  1 
ATOM   5388 C CG  . LEU   D 4 117 ? 153.920 93.281  92.313  1.00 72.57  ? 117 LEU   E CG  1 
ATOM   5389 C CD1 . LEU   D 4 117 ? 153.775 94.142  93.529  1.00 72.57  ? 117 LEU   E CD1 1 
ATOM   5390 C CD2 . LEU   D 4 117 ? 153.173 91.980  92.526  1.00 72.57  ? 117 LEU   E CD2 1 
ATOM   5391 N N   . THR   D 4 118 ? 154.923 91.480  89.435  1.00 77.46  ? 118 THR   E N   1 
ATOM   5392 C CA  . THR   D 4 118 ? 154.871 90.069  89.077  1.00 77.46  ? 118 THR   E CA  1 
ATOM   5393 C C   . THR   D 4 118 ? 155.311 89.236  90.269  1.00 77.46  ? 118 THR   E C   1 
ATOM   5394 O O   . THR   D 4 118 ? 156.382 89.476  90.835  1.00 77.46  ? 118 THR   E O   1 
ATOM   5395 C CB  . THR   D 4 118 ? 155.767 89.761  87.877  1.00 77.46  ? 118 THR   E CB  1 
ATOM   5396 O OG1 . THR   D 4 118 ? 157.139 89.787  88.287  1.00 77.46  ? 118 THR   E OG1 1 
ATOM   5397 C CG2 . THR   D 4 118 ? 155.558 90.782  86.771  1.00 77.46  ? 118 THR   E CG2 1 
ATOM   5398 N N   . VAL   D 4 119 ? 154.493 88.260  90.646  1.00 79.02  ? 119 VAL   E N   1 
ATOM   5399 C CA  . VAL   D 4 119 ? 154.816 87.334  91.723  1.00 79.02  ? 119 VAL   E CA  1 
ATOM   5400 C C   . VAL   D 4 119 ? 155.261 86.034  91.062  1.00 79.02  ? 119 VAL   E C   1 
ATOM   5401 O O   . VAL   D 4 119 ? 154.436 85.242  90.598  1.00 79.02  ? 119 VAL   E O   1 
ATOM   5402 C CB  . VAL   D 4 119 ? 153.631 87.121  92.667  1.00 79.02  ? 119 VAL   E CB  1 
ATOM   5403 N N   . SER   D 4 120 ? 156.571 85.813  91.017  1.00 79.57  ? 120 SER   E N   1 
ATOM   5404 C CA  . SER   D 4 120 ? 157.139 84.654  90.336  1.00 79.57  ? 120 SER   E CA  1 
ATOM   5405 C C   . SER   D 4 120 ? 156.834 83.356  91.068  1.00 79.57  ? 120 SER   E C   1 
ATOM   5406 O O   . SER   D 4 120 ? 157.351 82.299  90.709  1.00 79.57  ? 120 SER   E O   1 
ATOM   5407 C CB  . SER   D 4 120 ? 158.650 84.815  90.184  1.00 79.57  ? 120 SER   E CB  1 
ATOM   5408 O OG  . SER   D 4 120 ? 159.321 84.396  91.358  1.00 79.57  ? 120 SER   E OG  1 
ATOM   5409 N N   . SER   D 4 136 ? 126.413 90.313  99.885  1.00 82.13  ? 124 SER   E N   1 
ATOM   5410 C CA  . SER   D 4 136 ? 127.403 90.262  98.815  1.00 82.13  ? 124 SER   E CA  1 
ATOM   5411 C C   . SER   D 4 136 ? 127.558 91.625  98.148  1.00 82.13  ? 124 SER   E C   1 
ATOM   5412 O O   . SER   D 4 136 ? 126.857 92.576  98.490  1.00 82.13  ? 124 SER   E O   1 
ATOM   5413 C CB  . SER   D 4 136 ? 127.015 89.206  97.778  1.00 82.13  ? 124 SER   E CB  1 
ATOM   5414 O OG  . SER   D 4 136 ? 128.015 89.076  96.782  1.00 82.13  ? 124 SER   E OG  1 
ATOM   5415 N N   . ASP   D 4 137 ? 128.479 91.711  97.193  1.00 78.39  ? 125 ASP   E N   1 
ATOM   5416 C CA  . ASP   D 4 137 ? 128.738 92.959  96.497  1.00 78.39  ? 125 ASP   E CA  1 
ATOM   5417 C C   . ASP   D 4 137 ? 127.772 93.132  95.328  1.00 78.39  ? 125 ASP   E C   1 
ATOM   5418 O O   . ASP   D 4 137 ? 127.039 92.216  94.947  1.00 78.39  ? 125 ASP   E O   1 
ATOM   5419 C CB  . ASP   D 4 137 ? 130.183 93.004  96.005  1.00 78.39  ? 125 ASP   E CB  1 
ATOM   5420 C CG  . ASP   D 4 137 ? 131.180 92.664  97.096  1.00 78.39  ? 125 ASP   E CG  1 
ATOM   5421 O OD1 . ASP   D 4 137 ? 130.825 92.790  98.287  1.00 78.39  ? 125 ASP   E OD1 1 
ATOM   5422 O OD2 . ASP   D 4 137 ? 132.318 92.270  96.763  1.00 78.39  ? 125 ASP   E OD2 1 
ATOM   5423 N N   . ILE   D 4 138 ? 127.779 94.331  94.755  1.00 70.18  ? 126 ILE   E N   1 
ATOM   5424 C CA  . ILE   D 4 138 ? 126.893 94.653  93.625  1.00 70.18  ? 126 ILE   E CA  1 
ATOM   5425 C C   . ILE   D 4 138 ? 127.655 94.262  92.367  1.00 70.18  ? 126 ILE   E C   1 
ATOM   5426 O O   . ILE   D 4 138 ? 128.304 95.073  91.704  1.00 70.18  ? 126 ILE   E O   1 
ATOM   5427 C CB  . ILE   D 4 138 ? 126.471 96.122  93.623  1.00 70.18  ? 126 ILE   E CB  1 
ATOM   5428 C CG1 . ILE   D 4 138 ? 125.941 96.527  94.997  1.00 70.18  ? 126 ILE   E CG1 1 
ATOM   5429 C CG2 . ILE   D 4 138 ? 125.430 96.371  92.556  1.00 70.18  ? 126 ILE   E CG2 1 
ATOM   5430 C CD1 . ILE   D 4 138 ? 125.637 97.998  95.117  1.00 70.18  ? 126 ILE   E CD1 1 
ATOM   5431 N N   . VAL   D 4 139 ? 127.571 92.980  92.023  1.00 72.75  ? 127 VAL   E N   1 
ATOM   5432 C CA  . VAL   D 4 139 ? 128.243 92.495  90.825  1.00 72.75  ? 127 VAL   E CA  1 
ATOM   5433 C C   . VAL   D 4 139 ? 127.438 92.912  89.602  1.00 72.75  ? 127 VAL   E C   1 
ATOM   5434 O O   . VAL   D 4 139 ? 126.248 92.601  89.480  1.00 72.75  ? 127 VAL   E O   1 
ATOM   5435 C CB  . VAL   D 4 139 ? 128.456 90.975  90.886  1.00 72.75  ? 127 VAL   E CB  1 
ATOM   5436 C CG1 . VAL   D 4 139 ? 127.138 90.228  91.074  1.00 72.75  ? 127 VAL   E CG1 1 
ATOM   5437 C CG2 . VAL   D 4 139 ? 129.169 90.491  89.631  1.00 72.75  ? 127 VAL   E CG2 1 
ATOM   5438 N N   . MET   D 4 140 ? 128.078 93.647  88.701  1.00 70.04  ? 128 MET   E N   1 
ATOM   5439 C CA  . MET   D 4 140 ? 127.422 94.123  87.493  1.00 70.04  ? 128 MET   E CA  1 
ATOM   5440 C C   . MET   D 4 140 ? 128.278 93.813  86.281  1.00 70.04  ? 128 MET   E C   1 
ATOM   5441 O O   . MET   D 4 140 ? 129.490 94.040  86.293  1.00 70.04  ? 128 MET   E O   1 
ATOM   5442 C CB  . MET   D 4 140 ? 127.116 95.618  87.580  1.00 70.04  ? 128 MET   E CB  1 
ATOM   5443 C CG  . MET   D 4 140 ? 128.317 96.530  87.671  1.00 70.04  ? 128 MET   E CG  1 
ATOM   5444 S SD  . MET   D 4 140 ? 127.681 98.189  87.863  1.00 70.04  ? 128 MET   E SD  1 
ATOM   5445 C CE  . MET   D 4 140 ? 127.109 98.072  89.547  1.00 70.04  ? 128 MET   E CE  1 
ATOM   5446 N N   . THR   D 4 141 ? 127.639 93.287  85.241  1.00 71.95  ? 129 THR   E N   1 
ATOM   5447 C CA  . THR   D 4 141 ? 128.336 92.749  84.086  1.00 71.95  ? 129 THR   E CA  1 
ATOM   5448 C C   . THR   D 4 141 ? 127.829 93.413  82.820  1.00 71.95  ? 129 THR   E C   1 
ATOM   5449 O O   . THR   D 4 141 ? 126.619 93.507  82.605  1.00 71.95  ? 129 THR   E O   1 
ATOM   5450 C CB  . THR   D 4 141 ? 128.149 91.232  83.992  1.00 71.95  ? 129 THR   E CB  1 
ATOM   5451 O OG1 . THR   D 4 141 ? 126.762 90.913  84.160  1.00 71.95  ? 129 THR   E OG1 1 
ATOM   5452 C CG2 . THR   D 4 141 ? 128.957 90.531  85.071  1.00 71.95  ? 129 THR   E CG2 1 
ATOM   5453 N N   . GLN   D 4 142 ? 128.761 93.870  81.992  1.00 68.66  ? 130 GLN   E N   1 
ATOM   5454 C CA  . GLN   D 4 142 ? 128.452 94.403  80.674  1.00 68.66  ? 130 GLN   E CA  1 
ATOM   5455 C C   . GLN   D 4 142 ? 128.286 93.233  79.717  1.00 68.66  ? 130 GLN   E C   1 
ATOM   5456 O O   . GLN   D 4 142 ? 129.260 92.541  79.404  1.00 68.66  ? 130 GLN   E O   1 
ATOM   5457 C CB  . GLN   D 4 142 ? 129.565 95.329  80.204  1.00 68.66  ? 130 GLN   E CB  1 
ATOM   5458 C CG  . GLN   D 4 142 ? 129.844 96.466  81.139  1.00 68.66  ? 130 GLN   E CG  1 
ATOM   5459 C CD  . GLN   D 4 142 ? 130.971 97.338  80.659  1.00 68.66  ? 130 GLN   E CD  1 
ATOM   5460 O OE1 . GLN   D 4 142 ? 131.543 97.099  79.604  1.00 68.66  ? 130 GLN   E OE1 1 
ATOM   5461 N NE2 . GLN   D 4 142 ? 131.309 98.350  81.441  1.00 68.66  ? 130 GLN   E NE2 1 
ATOM   5462 N N   . ALA   D 4 143 ? 127.056 93.007  79.252  1.00 75.79  ? 131 ALA   E N   1 
ATOM   5463 C CA  . ALA   D 4 143 ? 126.793 91.849  78.404  1.00 75.79  ? 131 ALA   E CA  1 
ATOM   5464 C C   . ALA   D 4 143 ? 127.616 91.905  77.125  1.00 75.79  ? 131 ALA   E C   1 
ATOM   5465 O O   . ALA   D 4 143 ? 128.175 90.892  76.690  1.00 75.79  ? 131 ALA   E O   1 
ATOM   5466 C CB  . ALA   D 4 143 ? 125.301 91.761  78.082  1.00 75.79  ? 131 ALA   E CB  1 
ATOM   5467 N N   . THR   D 4 144 ? 127.709 93.080  76.517  1.00 76.74  ? 132 THR   E N   1 
ATOM   5468 C CA  . THR   D 4 144 ? 128.490 93.256  75.298  1.00 76.74  ? 132 THR   E CA  1 
ATOM   5469 C C   . THR   D 4 144 ? 129.963 93.249  75.675  1.00 76.74  ? 132 THR   E C   1 
ATOM   5470 O O   . THR   D 4 144 ? 130.524 94.275  76.063  1.00 76.74  ? 132 THR   E O   1 
ATOM   5471 C CB  . THR   D 4 144 ? 128.101 94.551  74.595  1.00 76.74  ? 132 THR   E CB  1 
ATOM   5472 N N   . SER   D 4 145 ? 130.595 92.085  75.569  1.00 77.18  ? 133 SER   E N   1 
ATOM   5473 C CA  . SER   D 4 145 ? 132.016 91.959  75.848  1.00 77.18  ? 133 SER   E CA  1 
ATOM   5474 C C   . SER   D 4 145 ? 132.891 92.271  74.643  1.00 77.18  ? 133 SER   E C   1 
ATOM   5475 O O   . SER   D 4 145 ? 134.108 92.400  74.800  1.00 77.18  ? 133 SER   E O   1 
ATOM   5476 C CB  . SER   D 4 145 ? 132.330 90.549  76.353  1.00 77.18  ? 133 SER   E CB  1 
ATOM   5477 O OG  . SER   D 4 145 ? 131.966 90.404  77.714  1.00 77.18  ? 133 SER   E OG  1 
ATOM   5478 N N   . SER   D 4 146 ? 132.309 92.392  73.454  1.00 79.91  ? 134 SER   E N   1 
ATOM   5479 C CA  . SER   D 4 146 ? 133.074 92.685  72.246  1.00 79.91  ? 134 SER   E CA  1 
ATOM   5480 C C   . SER   D 4 146 ? 132.116 93.236  71.205  1.00 79.91  ? 134 SER   E C   1 
ATOM   5481 O O   . SER   D 4 146 ? 131.180 92.540  70.801  1.00 79.91  ? 134 SER   E O   1 
ATOM   5482 C CB  . SER   D 4 146 ? 133.781 91.434  71.727  1.00 79.91  ? 134 SER   E CB  1 
ATOM   5483 N N   . VAL   D 4 147 ? 132.344 94.470  70.772  1.00 81.97  ? 135 VAL   E N   1 
ATOM   5484 C CA  . VAL   D 4 147 ? 131.441 95.145  69.845  1.00 81.97  ? 135 VAL   E CA  1 
ATOM   5485 C C   . VAL   D 4 147 ? 132.255 95.773  68.720  1.00 81.97  ? 135 VAL   E C   1 
ATOM   5486 O O   . VAL   D 4 147 ? 133.309 96.368  68.982  1.00 81.97  ? 135 VAL   E O   1 
ATOM   5487 C CB  . VAL   D 4 147 ? 130.591 96.197  70.577  1.00 81.97  ? 135 VAL   E CB  1 
ATOM   5488 C CG1 . VAL   D 4 147 ? 129.831 97.071  69.596  1.00 81.97  ? 135 VAL   E CG1 1 
ATOM   5489 C CG2 . VAL   D 4 147 ? 129.622 95.521  71.520  1.00 81.97  ? 135 VAL   E CG2 1 
ATOM   5490 N N   . PRO   D 4 148 ? 131.823 95.662  67.467  1.00 87.48  ? 136 PRO   E N   1 
ATOM   5491 C CA  . PRO   D 4 148 ? 132.519 96.348  66.377  1.00 87.48  ? 136 PRO   E CA  1 
ATOM   5492 C C   . PRO   D 4 148 ? 132.068 97.799  66.268  1.00 87.48  ? 136 PRO   E C   1 
ATOM   5493 O O   . PRO   D 4 148 ? 131.106 98.234  66.900  1.00 87.48  ? 136 PRO   E O   1 
ATOM   5494 C CB  . PRO   D 4 148 ? 132.108 95.546  65.142  1.00 87.48  ? 136 PRO   E CB  1 
ATOM   5495 C CG  . PRO   D 4 148 ? 130.748 95.040  65.477  1.00 87.48  ? 136 PRO   E CG  1 
ATOM   5496 C CD  . PRO   D 4 148 ? 130.674 94.880  66.978  1.00 87.48  ? 136 PRO   E CD  1 
ATOM   5497 N N   . VAL   D 4 149 ? 132.790 98.551  65.439  1.00 86.64  ? 137 VAL   E N   1 
ATOM   5498 C CA  . VAL   D 4 149 ? 132.503 99.967  65.251  1.00 86.64  ? 137 VAL   E CA  1 
ATOM   5499 C C   . VAL   D 4 149 ? 133.063 100.399 63.907  1.00 86.64  ? 137 VAL   E C   1 
ATOM   5500 O O   . VAL   D 4 149 ? 134.077 99.875  63.443  1.00 86.64  ? 137 VAL   E O   1 
ATOM   5501 C CB  . VAL   D 4 149 ? 133.090 100.811 66.410  1.00 86.64  ? 137 VAL   E CB  1 
ATOM   5502 N N   . THR   D 4 150 ? 132.396 101.363 63.281  1.00 85.47  ? 138 THR   E N   1 
ATOM   5503 C CA  . THR   D 4 150 ? 132.864 101.982 62.057  1.00 85.47  ? 138 THR   E CA  1 
ATOM   5504 C C   . THR   D 4 150 ? 132.894 103.491 62.248  1.00 85.47  ? 138 THR   E C   1 
ATOM   5505 O O   . THR   D 4 150 ? 131.995 104.051 62.885  1.00 85.47  ? 138 THR   E O   1 
ATOM   5506 C CB  . THR   D 4 150 ? 131.957 101.629 60.869  1.00 85.47  ? 138 THR   E CB  1 
ATOM   5507 O OG1 . THR   D 4 150 ? 130.678 102.252 61.040  1.00 85.47  ? 138 THR   E OG1 1 
ATOM   5508 C CG2 . THR   D 4 150 ? 131.772 100.123 60.761  1.00 85.47  ? 138 THR   E CG2 1 
ATOM   5509 N N   . PRO   D 4 151 ? 133.906 104.172 61.716  1.00 85.37  ? 139 PRO   E N   1 
ATOM   5510 C CA  . PRO   D 4 151 ? 134.023 105.616 61.951  1.00 85.37  ? 139 PRO   E CA  1 
ATOM   5511 C C   . PRO   D 4 151 ? 132.816 106.373 61.420  1.00 85.37  ? 139 PRO   E C   1 
ATOM   5512 O O   . PRO   D 4 151 ? 132.258 106.039 60.373  1.00 85.37  ? 139 PRO   E O   1 
ATOM   5513 C CB  . PRO   D 4 151 ? 135.302 105.996 61.198  1.00 85.37  ? 139 PRO   E CB  1 
ATOM   5514 C CG  . PRO   D 4 151 ? 136.074 104.727 61.100  1.00 85.37  ? 139 PRO   E CG  1 
ATOM   5515 C CD  . PRO   D 4 151 ? 135.054 103.638 60.969  1.00 85.37  ? 139 PRO   E CD  1 
ATOM   5516 N N   . GLY   D 4 152 ? 132.414 107.403 62.160  1.00 82.09  ? 140 GLY   E N   1 
ATOM   5517 C CA  . GLY   D 4 152 ? 131.255 108.192 61.805  1.00 82.09  ? 140 GLY   E CA  1 
ATOM   5518 C C   . GLY   D 4 152 ? 129.924 107.607 62.213  1.00 82.09  ? 140 GLY   E C   1 
ATOM   5519 O O   . GLY   D 4 152 ? 128.885 108.175 61.861  1.00 82.09  ? 140 GLY   E O   1 
ATOM   5520 N N   . GLU   D 4 153 ? 129.912 106.498 62.939  1.00 81.75  ? 141 GLU   E N   1 
ATOM   5521 C CA  . GLU   D 4 153 ? 128.683 105.842 63.353  1.00 81.75  ? 141 GLU   E CA  1 
ATOM   5522 C C   . GLU   D 4 153 ? 128.447 106.061 64.845  1.00 81.75  ? 141 GLU   E C   1 
ATOM   5523 O O   . GLU   D 4 153 ? 129.272 106.640 65.555  1.00 81.75  ? 141 GLU   E O   1 
ATOM   5524 C CB  . GLU   D 4 153 ? 128.731 104.352 63.012  1.00 81.75  ? 141 GLU   E CB  1 
ATOM   5525 N N   . SER   D 4 154 ? 127.296 105.592 65.315  1.00 78.57  ? 142 SER   E N   1 
ATOM   5526 C CA  . SER   D 4 154 ? 126.886 105.733 66.704  1.00 78.57  ? 142 SER   E CA  1 
ATOM   5527 C C   . SER   D 4 154 ? 126.793 104.357 67.347  1.00 78.57  ? 142 SER   E C   1 
ATOM   5528 O O   . SER   D 4 154 ? 126.183 103.443 66.782  1.00 78.57  ? 142 SER   E O   1 
ATOM   5529 C CB  . SER   D 4 154 ? 125.545 106.459 66.805  1.00 78.57  ? 142 SER   E CB  1 
ATOM   5530 O OG  . SER   D 4 154 ? 125.580 107.683 66.094  1.00 78.57  ? 142 SER   E OG  1 
ATOM   5531 N N   . VAL   D 4 155 ? 127.396 104.214 68.522  1.00 74.52  ? 143 VAL   E N   1 
ATOM   5532 C CA  . VAL   D 4 155 ? 127.479 102.941 69.223  1.00 74.52  ? 143 VAL   E CA  1 
ATOM   5533 C C   . VAL   D 4 155 ? 126.941 103.125 70.632  1.00 74.52  ? 143 VAL   E C   1 
ATOM   5534 O O   . VAL   D 4 155 ? 127.164 104.164 71.263  1.00 74.52  ? 143 VAL   E O   1 
ATOM   5535 C CB  . VAL   D 4 155 ? 128.924 102.401 69.252  1.00 74.52  ? 143 VAL   E CB  1 
ATOM   5536 C CG1 . VAL   D 4 155 ? 129.012 101.128 70.076  1.00 74.52  ? 143 VAL   E CG1 1 
ATOM   5537 C CG2 . VAL   D 4 155 ? 129.416 102.145 67.839  1.00 74.52  ? 143 VAL   E CG2 1 
ATOM   5538 N N   . SER   D 4 156 ? 126.220 102.122 71.118  1.00 69.78  ? 144 SER   E N   1 
ATOM   5539 C CA  . SER   D 4 156 ? 125.661 102.126 72.457  1.00 69.78  ? 144 SER   E CA  1 
ATOM   5540 C C   . SER   D 4 156 ? 126.253 100.975 73.255  1.00 69.78  ? 144 SER   E C   1 
ATOM   5541 O O   . SER   D 4 156 ? 126.284 99.836  72.780  1.00 69.78  ? 144 SER   E O   1 
ATOM   5542 C CB  . SER   D 4 156 ? 124.139 102.012 72.414  1.00 69.78  ? 144 SER   E CB  1 
ATOM   5543 O OG  . SER   D 4 156 ? 123.634 101.528 73.642  1.00 69.78  ? 144 SER   E OG  1 
ATOM   5544 N N   . ILE   D 4 157 ? 126.720 101.278 74.459  1.00 65.36  ? 145 ILE   E N   1 
ATOM   5545 C CA  . ILE   D 4 157 ? 127.206 100.280 75.399  1.00 65.36  ? 145 ILE   E CA  1 
ATOM   5546 C C   . ILE   D 4 157 ? 126.190 100.181 76.526  1.00 65.36  ? 145 ILE   E C   1 
ATOM   5547 O O   . ILE   D 4 157 ? 125.518 101.159 76.862  1.00 65.36  ? 145 ILE   E O   1 
ATOM   5548 C CB  . ILE   D 4 157 ? 128.608 100.657 75.919  1.00 65.36  ? 145 ILE   E CB  1 
ATOM   5549 C CG1 . ILE   D 4 157 ? 129.597 100.675 74.766  1.00 65.36  ? 145 ILE   E CG1 1 
ATOM   5550 C CG2 . ILE   D 4 157 ? 129.093 99.678  76.970  1.00 65.36  ? 145 ILE   E CG2 1 
ATOM   5551 C CD1 . ILE   D 4 157 ? 130.918 101.274 75.120  1.00 65.36  ? 145 ILE   E CD1 1 
ATOM   5552 N N   . SER   D 4 158 ? 126.064 98.993  77.106  1.00 67.83  ? 146 SER   E N   1 
ATOM   5553 C CA  . SER   D 4 158 ? 125.046 98.733  78.109  1.00 67.83  ? 146 SER   E CA  1 
ATOM   5554 C C   . SER   D 4 158 ? 125.672 98.108  79.344  1.00 67.83  ? 146 SER   E C   1 
ATOM   5555 O O   . SER   D 4 158 ? 126.655 97.371  79.255  1.00 67.83  ? 146 SER   E O   1 
ATOM   5556 C CB  . SER   D 4 158 ? 123.949 97.811  77.562  1.00 67.83  ? 146 SER   E CB  1 
ATOM   5557 O OG  . SER   D 4 158 ? 124.474 96.539  77.225  1.00 67.83  ? 146 SER   E OG  1 
ATOM   5558 N N   . CYS   D 4 159 ? 125.082 98.403  80.498  1.00 68.35  ? 147 CYS   E N   1 
ATOM   5559 C CA  . CYS   D 4 159 ? 125.588 97.911  81.776  1.00 68.35  ? 147 CYS   E CA  1 
ATOM   5560 C C   . CYS   D 4 159 ? 124.392 97.664  82.680  1.00 68.35  ? 147 CYS   E C   1 
ATOM   5561 O O   . CYS   D 4 159 ? 123.695 98.612  83.051  1.00 68.35  ? 147 CYS   E O   1 
ATOM   5562 C CB  . CYS   D 4 159 ? 126.559 98.909  82.407  1.00 68.35  ? 147 CYS   E CB  1 
ATOM   5563 S SG  . CYS   D 4 159 ? 127.255 98.419  84.015  1.00 68.35  ? 147 CYS   E SG  1 
ATOM   5564 N N   . ARG   D 4 160 ? 124.145 96.407  83.025  1.00 70.61  ? 148 ARG   E N   1 
ATOM   5565 C CA  . ARG   D 4 160 ? 123.062 96.063  83.932  1.00 70.61  ? 148 ARG   E CA  1 
ATOM   5566 C C   . ARG   D 4 160 ? 123.626 95.675  85.290  1.00 70.61  ? 148 ARG   E C   1 
ATOM   5567 O O   . ARG   D 4 160 ? 124.670 95.026  85.382  1.00 70.61  ? 148 ARG   E O   1 
ATOM   5568 C CB  . ARG   D 4 160 ? 122.196 94.935  83.372  1.00 70.61  ? 148 ARG   E CB  1 
ATOM   5569 C CG  . ARG   D 4 160 ? 122.891 93.604  83.200  1.00 70.61  ? 148 ARG   E CG  1 
ATOM   5570 C CD  . ARG   D 4 160 ? 121.899 92.533  82.777  1.00 70.61  ? 148 ARG   E CD  1 
ATOM   5571 N NE  . ARG   D 4 160 ? 122.560 91.271  82.458  1.00 70.61  ? 148 ARG   E NE  1 
ATOM   5572 C CZ  . ARG   D 4 160 ? 122.853 90.334  83.353  1.00 70.61  ? 148 ARG   E CZ  1 
ATOM   5573 N NH1 . ARG   D 4 160 ? 123.455 89.215  82.972  1.00 70.61  ? 148 ARG   E NH1 1 
ATOM   5574 N NH2 . ARG   D 4 160 ? 122.543 90.514  84.629  1.00 70.61  ? 148 ARG   E NH2 1 
ATOM   5575 N N   . SER   D 4 161 ? 122.932 96.083  86.337  1.00 68.85  ? 149 SER   E N   1 
ATOM   5576 C CA  . SER   D 4 161 ? 123.383 95.938  87.706  1.00 68.85  ? 149 SER   E CA  1 
ATOM   5577 C C   . SER   D 4 161 ? 122.635 94.809  88.400  1.00 68.85  ? 149 SER   E C   1 
ATOM   5578 O O   . SER   D 4 161 ? 121.736 94.181  87.837  1.00 68.85  ? 149 SER   E O   1 
ATOM   5579 C CB  . SER   D 4 161 ? 123.200 97.248  88.464  1.00 68.85  ? 149 SER   E CB  1 
ATOM   5580 O OG  . SER   D 4 161 ? 123.551 97.091  89.824  1.00 68.85  ? 149 SER   E OG  1 
ATOM   5581 N N   . SER   D 4 162 ? 123.023 94.559  89.649  1.00 69.07  ? 150 SER   E N   1 
ATOM   5582 C CA  . SER   D 4 162 ? 122.379 93.556  90.485  1.00 69.07  ? 150 SER   E CA  1 
ATOM   5583 C C   . SER   D 4 162 ? 121.299 94.186  91.355  1.00 69.07  ? 150 SER   E C   1 
ATOM   5584 O O   . SER   D 4 162 ? 120.123 93.820  91.263  1.00 69.07  ? 150 SER   E O   1 
ATOM   5585 C CB  . SER   D 4 162 ? 123.425 92.853  91.352  1.00 69.07  ? 150 SER   E CB  1 
ATOM   5586 O OG  . SER   D 4 162 ? 122.827 92.208  92.459  1.00 69.07  ? 150 SER   E OG  1 
ATOM   5587 N N   . LYS   D 4 163 ? 121.685 95.132  92.200  1.00 68.90  ? 151 LYS   E N   1 
ATOM   5588 C CA  . LYS   D 4 163 ? 120.749 95.924  92.974  1.00 68.90  ? 151 LYS   E CA  1 
ATOM   5589 C C   . LYS   D 4 163 ? 120.699 97.332  92.399  1.00 68.90  ? 151 LYS   E C   1 
ATOM   5590 O O   . LYS   D 4 163 ? 121.626 97.778  91.720  1.00 68.90  ? 151 LYS   E O   1 
ATOM   5591 C CB  . LYS   D 4 163 ? 121.140 95.949  94.456  1.00 68.90  ? 151 LYS   E CB  1 
ATOM   5592 C CG  . LYS   D 4 163 ? 122.131 97.028  94.832  1.00 68.90  ? 151 LYS   E CG  1 
ATOM   5593 C CD  . LYS   D 4 163 ? 122.368 97.042  96.333  1.00 68.90  ? 151 LYS   E CD  1 
ATOM   5594 C CE  . LYS   D 4 163 ? 121.367 97.940  97.042  1.00 68.90  ? 151 LYS   E CE  1 
ATOM   5595 N NZ  . LYS   D 4 163 ? 121.790 98.252  98.435  1.00 68.90  ? 151 LYS   E NZ  1 
ATOM   5596 N N   . SER   D 4 164 ? 119.592 98.022  92.658  1.00 68.87  ? 152 SER   E N   1 
ATOM   5597 C CA  . SER   D 4 164 ? 119.369 99.321  92.039  1.00 68.87  ? 152 SER   E CA  1 
ATOM   5598 C C   . SER   D 4 164 ? 120.425 100.320 92.479  1.00 68.87  ? 152 SER   E C   1 
ATOM   5599 O O   . SER   D 4 164 ? 120.801 100.382 93.652  1.00 68.87  ? 152 SER   E O   1 
ATOM   5600 C CB  . SER   D 4 164 ? 117.982 99.849  92.386  1.00 68.87  ? 152 SER   E CB  1 
ATOM   5601 O OG  . SER   D 4 164 ? 117.651 100.949 91.562  1.00 68.87  ? 152 SER   E OG  1 
ATOM   5602 N N   . LEU   D 4 165 ? 120.904 101.107 91.521  1.00 66.97  ? 153 LEU   E N   1 
ATOM   5603 C CA  . LEU   D 4 165 ? 121.914 102.122 91.769  1.00 66.97  ? 153 LEU   E CA  1 
ATOM   5604 C C   . LEU   D 4 165 ? 121.299 103.499 91.968  1.00 66.97  ? 153 LEU   E C   1 
ATOM   5605 O O   . LEU   D 4 165 ? 122.029 104.487 92.072  1.00 66.97  ? 153 LEU   E O   1 
ATOM   5606 C CB  . LEU   D 4 165 ? 122.922 102.138 90.623  1.00 66.97  ? 153 LEU   E CB  1 
ATOM   5607 C CG  . LEU   D 4 165 ? 124.198 101.319 90.829  1.00 66.97  ? 153 LEU   E CG  1 
ATOM   5608 C CD1 . LEU   D 4 165 ? 123.912 99.948  91.379  1.00 66.97  ? 153 LEU   E CD1 1 
ATOM   5609 C CD2 . LEU   D 4 165 ? 124.945 101.200 89.533  1.00 66.97  ? 153 LEU   E CD2 1 
ATOM   5610 N N   . LEU   D 4 166 ? 119.973 103.581 92.024  1.00 70.79  ? 154 LEU   E N   1 
ATOM   5611 C CA  . LEU   D 4 166 ? 119.268 104.820 92.328  1.00 70.79  ? 154 LEU   E CA  1 
ATOM   5612 C C   . LEU   D 4 166 ? 119.083 104.913 93.834  1.00 70.79  ? 154 LEU   E C   1 
ATOM   5613 O O   . LEU   D 4 166 ? 118.339 104.126 94.425  1.00 70.79  ? 154 LEU   E O   1 
ATOM   5614 C CB  . LEU   D 4 166 ? 117.920 104.870 91.617  1.00 70.79  ? 154 LEU   E CB  1 
ATOM   5615 C CG  . LEU   D 4 166 ? 117.128 106.159 91.823  1.00 70.79  ? 154 LEU   E CG  1 
ATOM   5616 C CD1 . LEU   D 4 166 ? 117.885 107.347 91.258  1.00 70.79  ? 154 LEU   E CD1 1 
ATOM   5617 C CD2 . LEU   D 4 166 ? 115.754 106.049 91.190  1.00 70.79  ? 154 LEU   E CD2 1 
ATOM   5618 N N   . HIS   D 4 167 ? 119.755 105.872 94.452  1.00 73.07  ? 155 HIS   E N   1 
ATOM   5619 C CA  . HIS   D 4 167 ? 119.613 106.072 95.879  1.00 73.07  ? 155 HIS   E CA  1 
ATOM   5620 C C   . HIS   D 4 167 ? 118.354 106.881 96.172  1.00 73.07  ? 155 HIS   E C   1 
ATOM   5621 O O   . HIS   D 4 167 ? 117.681 107.389 95.271  1.00 73.07  ? 155 HIS   E O   1 
ATOM   5622 C CB  . HIS   D 4 167 ? 120.846 106.767 96.438  1.00 73.07  ? 155 HIS   E CB  1 
ATOM   5623 C CG  . HIS   D 4 167 ? 121.099 106.480 97.881  1.00 73.07  ? 155 HIS   E CG  1 
ATOM   5624 N ND1 . HIS   D 4 167 ? 120.625 107.284 98.892  1.00 73.07  ? 155 HIS   E ND1 1 
ATOM   5625 C CD2 . HIS   D 4 167 ? 121.783 105.481 98.484  1.00 73.07  ? 155 HIS   E CD2 1 
ATOM   5626 C CE1 . HIS   D 4 167 ? 121.004 106.792 100.057 1.00 73.07  ? 155 HIS   E CE1 1 
ATOM   5627 N NE2 . HIS   D 4 167 ? 121.708 105.698 99.837  1.00 73.07  ? 155 HIS   E NE2 1 
ATOM   5628 N N   . SER   D 4 168 ? 118.036 106.999 97.462  1.00 73.47  ? 156 SER   E N   1 
ATOM   5629 C CA  . SER   D 4 168 ? 116.858 107.749 97.874  1.00 73.47  ? 156 SER   E CA  1 
ATOM   5630 C C   . SER   D 4 168 ? 116.987 109.242 97.602  1.00 73.47  ? 156 SER   E C   1 
ATOM   5631 O O   . SER   D 4 168 ? 115.973 109.947 97.608  1.00 73.47  ? 156 SER   E O   1 
ATOM   5632 C CB  . SER   D 4 168 ? 116.587 107.520 99.358  1.00 73.47  ? 156 SER   E CB  1 
ATOM   5633 O OG  . SER   D 4 168 ? 117.469 108.288 100.155 1.00 73.47  ? 156 SER   E OG  1 
ATOM   5634 N N   . ASN   D 4 169 ? 118.201 109.739 97.364  1.00 72.44  ? 157 ASN   E N   1 
ATOM   5635 C CA  . ASN   D 4 169 ? 118.437 111.161 97.171  1.00 72.44  ? 157 ASN   E CA  1 
ATOM   5636 C C   . ASN   D 4 169 ? 118.480 111.556 95.700  1.00 72.44  ? 157 ASN   E C   1 
ATOM   5637 O O   . ASN   D 4 169 ? 119.026 112.610 95.365  1.00 72.44  ? 157 ASN   E O   1 
ATOM   5638 C CB  . ASN   D 4 169 ? 119.726 111.583 97.876  1.00 72.44  ? 157 ASN   E CB  1 
ATOM   5639 C CG  . ASN   D 4 169 ? 120.893 110.670 97.563  1.00 72.44  ? 157 ASN   E CG  1 
ATOM   5640 O OD1 . ASN   D 4 169 ? 120.890 109.959 96.559  1.00 72.44  ? 157 ASN   E OD1 1 
ATOM   5641 N ND2 . ASN   D 4 169 ? 121.895 110.678 98.428  1.00 72.44  ? 157 ASN   E ND2 1 
ATOM   5642 N N   . GLY   D 4 170 ? 117.920 110.733 94.818  1.00 72.73  ? 158 GLY   E N   1 
ATOM   5643 C CA  . GLY   D 4 170 ? 117.824 111.072 93.414  1.00 72.73  ? 158 GLY   E CA  1 
ATOM   5644 C C   . GLY   D 4 170 ? 119.101 110.934 92.622  1.00 72.73  ? 158 GLY   E C   1 
ATOM   5645 O O   . GLY   D 4 170 ? 119.140 111.354 91.461  1.00 72.73  ? 158 GLY   E O   1 
ATOM   5646 N N   . ASN   D 4 171 ? 120.143 110.356 93.202  1.00 70.03  ? 159 ASN   E N   1 
ATOM   5647 C CA  . ASN   D 4 171 ? 121.439 110.232 92.558  1.00 70.03  ? 159 ASN   E CA  1 
ATOM   5648 C C   . ASN   D 4 171 ? 121.670 108.785 92.152  1.00 70.03  ? 159 ASN   E C   1 
ATOM   5649 O O   . ASN   D 4 171 ? 121.465 107.871 92.955  1.00 70.03  ? 159 ASN   E O   1 
ATOM   5650 C CB  . ASN   D 4 171 ? 122.552 110.702 93.492  1.00 70.03  ? 159 ASN   E CB  1 
ATOM   5651 C CG  . ASN   D 4 171 ? 122.911 112.148 93.281  1.00 70.03  ? 159 ASN   E CG  1 
ATOM   5652 O OD1 . ASN   D 4 171 ? 122.854 112.656 92.163  1.00 70.03  ? 159 ASN   E OD1 1 
ATOM   5653 N ND2 . ASN   D 4 171 ? 123.285 112.825 94.355  1.00 70.03  ? 159 ASN   E ND2 1 
ATOM   5654 N N   . THR   D 4 172 ? 122.088 108.583 90.911  1.00 66.75  ? 160 THR   E N   1 
ATOM   5655 C CA  . THR   D 4 172 ? 122.495 107.274 90.422  1.00 66.75  ? 160 THR   E CA  1 
ATOM   5656 C C   . THR   D 4 172 ? 124.013 107.238 90.405  1.00 66.75  ? 160 THR   E C   1 
ATOM   5657 O O   . THR   D 4 172 ? 124.645 107.904 89.581  1.00 66.75  ? 160 THR   E O   1 
ATOM   5658 C CB  . THR   D 4 172 ? 121.931 106.991 89.034  1.00 66.75  ? 160 THR   E CB  1 
ATOM   5659 O OG1 . THR   D 4 172 ? 120.557 107.391 88.985  1.00 66.75  ? 160 THR   E OG1 1 
ATOM   5660 C CG2 . THR   D 4 172 ? 122.020 105.517 88.736  1.00 66.75  ? 160 THR   E CG2 1 
ATOM   5661 N N   . TYR   D 4 173 ? 124.596 106.448 91.301  1.00 63.20  ? 161 TYR   E N   1 
ATOM   5662 C CA  . TYR   D 4 173 ? 126.044 106.387 91.460  1.00 63.20  ? 161 TYR   E CA  1 
ATOM   5663 C C   . TYR   D 4 173 ? 126.621 105.332 90.521  1.00 63.20  ? 161 TYR   E C   1 
ATOM   5664 O O   . TYR   D 4 173 ? 127.010 104.239 90.925  1.00 63.20  ? 161 TYR   E O   1 
ATOM   5665 C CB  . TYR   D 4 173 ? 126.396 106.092 92.907  1.00 63.20  ? 161 TYR   E CB  1 
ATOM   5666 C CG  . TYR   D 4 173 ? 125.985 107.165 93.878  1.00 63.20  ? 161 TYR   E CG  1 
ATOM   5667 C CD1 . TYR   D 4 173 ? 126.631 108.382 93.908  1.00 63.20  ? 161 TYR   E CD1 1 
ATOM   5668 C CD2 . TYR   D 4 173 ? 124.958 106.950 94.777  1.00 63.20  ? 161 TYR   E CD2 1 
ATOM   5669 C CE1 . TYR   D 4 173 ? 126.264 109.357 94.800  1.00 63.20  ? 161 TYR   E CE1 1 
ATOM   5670 C CE2 . TYR   D 4 173 ? 124.584 107.919 95.671  1.00 63.20  ? 161 TYR   E CE2 1 
ATOM   5671 C CZ  . TYR   D 4 173 ? 125.241 109.121 95.679  1.00 63.20  ? 161 TYR   E CZ  1 
ATOM   5672 O OH  . TYR   D 4 173 ? 124.871 110.098 96.570  1.00 63.20  ? 161 TYR   E OH  1 
ATOM   5673 N N   . LEU   D 4 174 ? 126.675 105.673 89.240  1.00 60.20  ? 162 LEU   E N   1 
ATOM   5674 C CA  . LEU   D 4 174 ? 127.311 104.835 88.237  1.00 60.20  ? 162 LEU   E CA  1 
ATOM   5675 C C   . LEU   D 4 174 ? 128.250 105.677 87.390  1.00 60.20  ? 162 LEU   E C   1 
ATOM   5676 O O   . LEU   D 4 174 ? 127.909 106.790 86.986  1.00 60.20  ? 162 LEU   E O   1 
ATOM   5677 C CB  . LEU   D 4 174 ? 126.283 104.125 87.352  1.00 60.20  ? 162 LEU   E CB  1 
ATOM   5678 C CG  . LEU   D 4 174 ? 126.884 103.173 86.321  1.00 60.20  ? 162 LEU   E CG  1 
ATOM   5679 C CD1 . LEU   D 4 174 ? 126.089 101.907 86.228  1.00 60.20  ? 162 LEU   E CD1 1 
ATOM   5680 C CD2 . LEU   D 4 174 ? 126.916 103.840 84.969  1.00 60.20  ? 162 LEU   E CD2 1 
ATOM   5681 N N   . TYR   D 4 175 ? 129.431 105.131 87.119  1.00 57.68  ? 163 TYR   E N   1 
ATOM   5682 C CA  . TYR   D 4 175 ? 130.520 105.858 86.494  1.00 57.68  ? 163 TYR   E CA  1 
ATOM   5683 C C   . TYR   D 4 175 ? 130.983 105.114 85.250  1.00 57.68  ? 163 TYR   E C   1 
ATOM   5684 O O   . TYR   D 4 175 ? 130.974 103.884 85.214  1.00 57.68  ? 163 TYR   E O   1 
ATOM   5685 C CB  . TYR   D 4 175 ? 131.689 106.028 87.477  1.00 57.68  ? 163 TYR   E CB  1 
ATOM   5686 C CG  . TYR   D 4 175 ? 131.399 106.961 88.625  1.00 57.68  ? 163 TYR   E CG  1 
ATOM   5687 C CD1 . TYR   D 4 175 ? 132.036 108.181 88.724  1.00 57.68  ? 163 TYR   E CD1 1 
ATOM   5688 C CD2 . TYR   D 4 175 ? 130.493 106.625 89.605  1.00 57.68  ? 163 TYR   E CD2 1 
ATOM   5689 C CE1 . TYR   D 4 175 ? 131.771 109.037 89.760  1.00 57.68  ? 163 TYR   E CE1 1 
ATOM   5690 C CE2 . TYR   D 4 175 ? 130.219 107.479 90.640  1.00 57.68  ? 163 TYR   E CE2 1 
ATOM   5691 C CZ  . TYR   D 4 175 ? 130.858 108.680 90.711  1.00 57.68  ? 163 TYR   E CZ  1 
ATOM   5692 O OH  . TYR   D 4 175 ? 130.581 109.523 91.753  1.00 57.68  ? 163 TYR   E OH  1 
ATOM   5693 N N   . TRP   D 4 176 ? 131.386 105.861 84.231  1.00 57.69  ? 164 TRP   E N   1 
ATOM   5694 C CA  . TRP   D 4 176 ? 131.872 105.293 82.980  1.00 57.69  ? 164 TRP   E CA  1 
ATOM   5695 C C   . TRP   D 4 176 ? 133.325 105.683 82.767  1.00 57.69  ? 164 TRP   E C   1 
ATOM   5696 O O   . TRP   D 4 176 ? 133.675 106.859 82.881  1.00 57.69  ? 164 TRP   E O   1 
ATOM   5697 C CB  . TRP   D 4 176 ? 131.028 105.762 81.790  1.00 57.69  ? 164 TRP   E CB  1 
ATOM   5698 C CG  . TRP   D 4 176 ? 129.721 105.061 81.678  1.00 57.69  ? 164 TRP   E CG  1 
ATOM   5699 C CD1 . TRP   D 4 176 ? 128.513 105.516 82.103  1.00 57.69  ? 164 TRP   E CD1 1 
ATOM   5700 C CD2 . TRP   D 4 176 ? 129.487 103.772 81.114  1.00 57.69  ? 164 TRP   E CD2 1 
ATOM   5701 N NE1 . TRP   D 4 176 ? 127.541 104.594 81.840  1.00 57.69  ? 164 TRP   E NE1 1 
ATOM   5702 C CE2 . TRP   D 4 176 ? 128.115 103.510 81.234  1.00 57.69  ? 164 TRP   E CE2 1 
ATOM   5703 C CE3 . TRP   D 4 176 ? 130.305 102.809 80.525  1.00 57.69  ? 164 TRP   E CE3 1 
ATOM   5704 C CZ2 . TRP   D 4 176 ? 127.542 102.329 80.784  1.00 57.69  ? 164 TRP   E CZ2 1 
ATOM   5705 C CZ3 . TRP   D 4 176 ? 129.731 101.637 80.080  1.00 57.69  ? 164 TRP   E CZ3 1 
ATOM   5706 C CH2 . TRP   D 4 176 ? 128.368 101.408 80.210  1.00 57.69  ? 164 TRP   E CH2 1 
ATOM   5707 N N   . PHE   D 4 177 ? 134.163 104.702 82.452  1.00 55.25  ? 165 PHE   E N   1 
ATOM   5708 C CA  . PHE   D 4 177 ? 135.590 104.904 82.251  1.00 55.25  ? 165 PHE   E CA  1 
ATOM   5709 C C   . PHE   D 4 177 ? 135.991 104.461 80.853  1.00 55.25  ? 165 PHE   E C   1 
ATOM   5710 O O   . PHE   D 4 177 ? 135.236 103.790 80.147  1.00 55.25  ? 165 PHE   E O   1 
ATOM   5711 C CB  . PHE   D 4 177 ? 136.410 104.145 83.293  1.00 55.25  ? 165 PHE   E CB  1 
ATOM   5712 C CG  . PHE   D 4 177 ? 136.257 104.674 84.667  1.00 55.25  ? 165 PHE   E CG  1 
ATOM   5713 C CD1 . PHE   D 4 177 ? 135.555 103.969 85.610  1.00 55.25  ? 165 PHE   E CD1 1 
ATOM   5714 C CD2 . PHE   D 4 177 ? 136.791 105.885 85.013  1.00 55.25  ? 165 PHE   E CD2 1 
ATOM   5715 C CE1 . PHE   D 4 177 ? 135.404 104.458 86.859  1.00 55.25  ? 165 PHE   E CE1 1 
ATOM   5716 C CE2 . PHE   D 4 177 ? 136.637 106.371 86.275  1.00 55.25  ? 165 PHE   E CE2 1 
ATOM   5717 C CZ  . PHE   D 4 177 ? 135.939 105.654 87.197  1.00 55.25  ? 165 PHE   E CZ  1 
ATOM   5718 N N   . LEU   D 4 178 ? 137.199 104.844 80.456  1.00 59.32  ? 166 LEU   E N   1 
ATOM   5719 C CA  . LEU   D 4 178 ? 137.703 104.526 79.128  1.00 59.32  ? 166 LEU   E CA  1 
ATOM   5720 C C   . LEU   D 4 178 ? 139.211 104.367 79.197  1.00 59.32  ? 166 LEU   E C   1 
ATOM   5721 O O   . LEU   D 4 178 ? 139.907 105.279 79.648  1.00 59.32  ? 166 LEU   E O   1 
ATOM   5722 C CB  . LEU   D 4 178 ? 137.324 105.612 78.134  1.00 59.32  ? 166 LEU   E CB  1 
ATOM   5723 C CG  . LEU   D 4 178 ? 138.160 105.711 76.863  1.00 59.32  ? 166 LEU   E CG  1 
ATOM   5724 C CD1 . LEU   D 4 178 ? 138.070 104.441 76.033  1.00 59.32  ? 166 LEU   E CD1 1 
ATOM   5725 C CD2 . LEU   D 4 178 ? 137.712 106.906 76.051  1.00 59.32  ? 166 LEU   E CD2 1 
ATOM   5726 N N   . GLN   D 4 179 ? 139.713 103.226 78.737  1.00 63.34  ? 167 GLN   E N   1 
ATOM   5727 C CA  . GLN   D 4 179 ? 141.144 102.947 78.692  1.00 63.34  ? 167 GLN   E CA  1 
ATOM   5728 C C   . GLN   D 4 179 ? 141.575 102.775 77.245  1.00 63.34  ? 167 GLN   E C   1 
ATOM   5729 O O   . GLN   D 4 179 ? 141.222 101.782 76.601  1.00 63.34  ? 167 GLN   E O   1 
ATOM   5730 C CB  . GLN   D 4 179 ? 141.487 101.701 79.494  1.00 63.34  ? 167 GLN   E CB  1 
ATOM   5731 C CG  . GLN   D 4 179 ? 142.865 101.169 79.200  1.00 63.34  ? 167 GLN   E CG  1 
ATOM   5732 C CD  . GLN   D 4 179 ? 143.440 100.375 80.345  1.00 63.34  ? 167 GLN   E CD  1 
ATOM   5733 O OE1 . GLN   D 4 179 ? 142.707 99.811  81.154  1.00 63.34  ? 167 GLN   E OE1 1 
ATOM   5734 N NE2 . GLN   D 4 179 ? 144.761 100.320 80.419  1.00 63.34  ? 167 GLN   E NE2 1 
ATOM   5735 N N   . ARG   D 4 180 ? 142.333 103.735 76.735  1.00 68.99  ? 168 ARG   E N   1 
ATOM   5736 C CA  . ARG   D 4 180 ? 142.883 103.623 75.401  1.00 68.99  ? 168 ARG   E CA  1 
ATOM   5737 C C   . ARG   D 4 180 ? 144.007 102.592 75.396  1.00 68.99  ? 168 ARG   E C   1 
ATOM   5738 O O   . ARG   D 4 180 ? 144.541 102.242 76.450  1.00 68.99  ? 168 ARG   E O   1 
ATOM   5739 C CB  . ARG   D 4 180 ? 143.389 104.980 74.926  1.00 68.99  ? 168 ARG   E CB  1 
ATOM   5740 C CG  . ARG   D 4 180 ? 142.329 105.813 74.255  1.00 68.99  ? 168 ARG   E CG  1 
ATOM   5741 C CD  . ARG   D 4 180 ? 142.790 107.242 74.078  1.00 68.99  ? 168 ARG   E CD  1 
ATOM   5742 N NE  . ARG   D 4 180 ? 141.678 108.170 73.920  1.00 68.99  ? 168 ARG   E NE  1 
ATOM   5743 C CZ  . ARG   D 4 180 ? 140.822 108.494 74.881  1.00 68.99  ? 168 ARG   E CZ  1 
ATOM   5744 N NH1 . ARG   D 4 180 ? 140.945 107.975 76.093  1.00 68.99  ? 168 ARG   E NH1 1 
ATOM   5745 N NH2 . ARG   D 4 180 ? 139.844 109.349 74.634  1.00 68.99  ? 168 ARG   E NH2 1 
ATOM   5746 N N   . PRO   D 4 181 ? 144.364 102.065 74.224  1.00 72.33  ? 169 PRO   E N   1 
ATOM   5747 C CA  . PRO   D 4 181 ? 145.408 101.031 74.168  1.00 72.33  ? 169 PRO   E CA  1 
ATOM   5748 C C   . PRO   D 4 181 ? 146.707 101.493 74.810  1.00 72.33  ? 169 PRO   E C   1 
ATOM   5749 O O   . PRO   D 4 181 ? 147.356 102.430 74.342  1.00 72.33  ? 169 PRO   E O   1 
ATOM   5750 C CB  . PRO   D 4 181 ? 145.577 100.788 72.665  1.00 72.33  ? 169 PRO   E CB  1 
ATOM   5751 C CG  . PRO   D 4 181 ? 144.268 101.147 72.086  1.00 72.33  ? 169 PRO   E CG  1 
ATOM   5752 C CD  . PRO   D 4 181 ? 143.748 102.287 72.905  1.00 72.33  ? 169 PRO   E CD  1 
ATOM   5753 N N   . GLY   D 4 182 ? 147.083 100.820 75.895  1.00 71.63  ? 170 GLY   E N   1 
ATOM   5754 C CA  . GLY   D 4 182 ? 148.348 101.087 76.549  1.00 71.63  ? 170 GLY   E CA  1 
ATOM   5755 C C   . GLY   D 4 182 ? 148.412 102.366 77.348  1.00 71.63  ? 170 GLY   E C   1 
ATOM   5756 O O   . GLY   D 4 182 ? 149.482 102.973 77.440  1.00 71.63  ? 170 GLY   E O   1 
ATOM   5757 N N   . GLN   D 4 183 ? 147.300 102.796 77.935  1.00 69.31  ? 171 GLN   E N   1 
ATOM   5758 C CA  . GLN   D 4 183 ? 147.272 104.020 78.719  1.00 69.31  ? 171 GLN   E CA  1 
ATOM   5759 C C   . GLN   D 4 183 ? 146.385 103.830 79.938  1.00 69.31  ? 171 GLN   E C   1 
ATOM   5760 O O   . GLN   D 4 183 ? 145.566 102.910 80.005  1.00 69.31  ? 171 GLN   E O   1 
ATOM   5761 C CB  . GLN   D 4 183 ? 146.771 105.214 77.900  1.00 69.31  ? 171 GLN   E CB  1 
ATOM   5762 C CG  . GLN   D 4 183 ? 147.865 106.000 77.222  1.00 69.31  ? 171 GLN   E CG  1 
ATOM   5763 C CD  . GLN   D 4 183 ? 147.336 106.890 76.126  1.00 69.31  ? 171 GLN   E CD  1 
ATOM   5764 O OE1 . GLN   D 4 183 ? 146.359 107.614 76.315  1.00 69.31  ? 171 GLN   E OE1 1 
ATOM   5765 N NE2 . GLN   D 4 183 ? 147.979 106.846 74.966  1.00 69.31  ? 171 GLN   E NE2 1 
ATOM   5766 N N   . SER   D 4 184 ? 146.564 104.720 80.905  1.00 61.52  ? 172 SER   E N   1 
ATOM   5767 C CA  . SER   D 4 184 ? 145.736 104.720 82.093  1.00 61.52  ? 172 SER   E CA  1 
ATOM   5768 C C   . SER   D 4 184 ? 144.328 105.209 81.761  1.00 61.52  ? 172 SER   E C   1 
ATOM   5769 O O   . SER   D 4 184 ? 144.152 106.080 80.907  1.00 61.52  ? 172 SER   E O   1 
ATOM   5770 C CB  . SER   D 4 184 ? 146.360 105.609 83.158  1.00 61.52  ? 172 SER   E CB  1 
ATOM   5771 O OG  . SER   D 4 184 ? 145.406 105.968 84.129  1.00 61.52  ? 172 SER   E OG  1 
ATOM   5772 N N   . PRO   D 4 185 ? 143.309 104.661 82.415  1.00 58.66  ? 173 PRO   E N   1 
ATOM   5773 C CA  . PRO   D 4 185 ? 141.927 104.968 82.026  1.00 58.66  ? 173 PRO   E CA  1 
ATOM   5774 C C   . PRO   D 4 185 ? 141.516 106.381 82.411  1.00 58.66  ? 173 PRO   E C   1 
ATOM   5775 O O   . PRO   D 4 185 ? 142.171 107.076 83.188  1.00 58.66  ? 173 PRO   E O   1 
ATOM   5776 C CB  . PRO   D 4 185 ? 141.086 103.925 82.763  1.00 58.66  ? 173 PRO   E CB  1 
ATOM   5777 C CG  . PRO   D 4 185 ? 141.981 103.225 83.664  1.00 58.66  ? 173 PRO   E CG  1 
ATOM   5778 C CD  . PRO   D 4 185 ? 143.396 103.527 83.343  1.00 58.66  ? 173 PRO   E CD  1 
ATOM   5779 N N   . GLN   D 4 186 ? 140.390 106.795 81.839  1.00 59.27  ? 174 GLN   E N   1 
ATOM   5780 C CA  . GLN   D 4 186 ? 139.930 108.173 81.879  1.00 59.27  ? 174 GLN   E CA  1 
ATOM   5781 C C   . GLN   D 4 186 ? 138.435 108.209 82.143  1.00 59.27  ? 174 GLN   E C   1 
ATOM   5782 O O   . GLN   D 4 186 ? 137.684 107.390 81.609  1.00 59.27  ? 174 GLN   E O   1 
ATOM   5783 C CB  . GLN   D 4 186 ? 140.251 108.878 80.561  1.00 59.27  ? 174 GLN   E CB  1 
ATOM   5784 C CG  . GLN   D 4 186 ? 139.692 110.271 80.422  1.00 59.27  ? 174 GLN   E CG  1 
ATOM   5785 C CD  . GLN   D 4 186 ? 140.052 110.892 79.093  1.00 59.27  ? 174 GLN   E CD  1 
ATOM   5786 O OE1 . GLN   D 4 186 ? 140.763 110.290 78.291  1.00 59.27  ? 174 GLN   E OE1 1 
ATOM   5787 N NE2 . GLN   D 4 186 ? 139.562 112.101 78.850  1.00 59.27  ? 174 GLN   E NE2 1 
ATOM   5788 N N   . LEU   D 4 187 ? 138.008 109.166 82.956  1.00 55.93  ? 175 LEU   E N   1 
ATOM   5789 C CA  . LEU   D 4 187 ? 136.604 109.291 83.314  1.00 55.93  ? 175 LEU   E CA  1 
ATOM   5790 C C   . LEU   D 4 187 ? 135.815 109.949 82.193  1.00 55.93  ? 175 LEU   E C   1 
ATOM   5791 O O   . LEU   D 4 187 ? 136.277 110.905 81.567  1.00 55.93  ? 175 LEU   E O   1 
ATOM   5792 C CB  . LEU   D 4 187 ? 136.463 110.100 84.601  1.00 55.93  ? 175 LEU   E CB  1 
ATOM   5793 C CG  . LEU   D 4 187 ? 135.094 110.342 85.226  1.00 55.93  ? 175 LEU   E CG  1 
ATOM   5794 C CD1 . LEU   D 4 187 ? 134.570 109.120 85.918  1.00 55.93  ? 175 LEU   E CD1 1 
ATOM   5795 C CD2 . LEU   D 4 187 ? 135.195 111.483 86.202  1.00 55.93  ? 175 LEU   E CD2 1 
ATOM   5796 N N   . LEU   D 4 188 ? 134.617 109.424 81.941  1.00 58.32  ? 176 LEU   E N   1 
ATOM   5797 C CA  . LEU   D 4 188 ? 133.705 109.981 80.951  1.00 58.32  ? 176 LEU   E CA  1 
ATOM   5798 C C   . LEU   D 4 188 ? 132.427 110.522 81.563  1.00 58.32  ? 176 LEU   E C   1 
ATOM   5799 O O   . LEU   D 4 188 ? 132.066 111.677 81.319  1.00 58.32  ? 176 LEU   E O   1 
ATOM   5800 C CB  . LEU   D 4 188 ? 133.345 108.923 79.904  1.00 58.32  ? 176 LEU   E CB  1 
ATOM   5801 C CG  . LEU   D 4 188 ? 134.475 108.240 79.163  1.00 58.32  ? 176 LEU   E CG  1 
ATOM   5802 C CD1 . LEU   D 4 188 ? 133.920 107.056 78.413  1.00 58.32  ? 176 LEU   E CD1 1 
ATOM   5803 C CD2 . LEU   D 4 188 ? 135.118 109.209 78.218  1.00 58.32  ? 176 LEU   E CD2 1 
ATOM   5804 N N   . ILE   D 4 189 ? 131.722 109.710 82.339  1.00 57.56  ? 177 ILE   E N   1 
ATOM   5805 C CA  . ILE   D 4 189 ? 130.402 110.036 82.854  1.00 57.56  ? 177 ILE   E CA  1 
ATOM   5806 C C   . ILE   D 4 189 ? 130.407 109.760 84.344  1.00 57.56  ? 177 ILE   E C   1 
ATOM   5807 O O   . ILE   D 4 189 ? 130.716 108.640 84.764  1.00 57.56  ? 177 ILE   E O   1 
ATOM   5808 C CB  . ILE   D 4 189 ? 129.303 109.211 82.166  1.00 57.56  ? 177 ILE   E CB  1 
ATOM   5809 C CG1 . ILE   D 4 189 ? 129.258 109.517 80.675  1.00 57.56  ? 177 ILE   E CG1 1 
ATOM   5810 C CG2 . ILE   D 4 189 ? 127.959 109.475 82.804  1.00 57.56  ? 177 ILE   E CG2 1 
ATOM   5811 C CD1 . ILE   D 4 189 ? 128.515 110.769 80.344  1.00 57.56  ? 177 ILE   E CD1 1 
ATOM   5812 N N   . TYR   D 4 190 ? 130.074 110.762 85.143  1.00 59.11  ? 178 TYR   E N   1 
ATOM   5813 C CA  . TYR   D 4 190 ? 129.865 110.542 86.562  1.00 59.11  ? 178 TYR   E CA  1 
ATOM   5814 C C   . TYR   D 4 190 ? 128.412 110.810 86.916  1.00 59.11  ? 178 TYR   E C   1 
ATOM   5815 O O   . TYR   D 4 190 ? 127.822 111.799 86.469  1.00 59.11  ? 178 TYR   E O   1 
ATOM   5816 C CB  . TYR   D 4 190 ? 130.805 111.386 87.433  1.00 59.11  ? 178 TYR   E CB  1 
ATOM   5817 C CG  . TYR   D 4 190 ? 130.919 112.847 87.102  1.00 59.11  ? 178 TYR   E CG  1 
ATOM   5818 C CD1 . TYR   D 4 190 ? 131.873 113.298 86.214  1.00 59.11  ? 178 TYR   E CD1 1 
ATOM   5819 C CD2 . TYR   D 4 190 ? 130.122 113.780 87.727  1.00 59.11  ? 178 TYR   E CD2 1 
ATOM   5820 C CE1 . TYR   D 4 190 ? 132.000 114.629 85.929  1.00 59.11  ? 178 TYR   E CE1 1 
ATOM   5821 C CE2 . TYR   D 4 190 ? 130.240 115.111 87.445  1.00 59.11  ? 178 TYR   E CE2 1 
ATOM   5822 C CZ  . TYR   D 4 190 ? 131.177 115.532 86.547  1.00 59.11  ? 178 TYR   E CZ  1 
ATOM   5823 O OH  . TYR   D 4 190 ? 131.296 116.870 86.264  1.00 59.11  ? 178 TYR   E OH  1 
ATOM   5824 N N   . ARG   D 4 191 ? 127.846 109.896 87.699  1.00 63.42  ? 179 ARG   E N   1 
ATOM   5825 C CA  . ARG   D 4 191 ? 126.463 109.961 88.160  1.00 63.42  ? 179 ARG   E CA  1 
ATOM   5826 C C   . ARG   D 4 191 ? 125.474 109.850 87.001  1.00 63.42  ? 179 ARG   E C   1 
ATOM   5827 O O   . ARG   D 4 191 ? 124.424 110.492 86.991  1.00 63.42  ? 179 ARG   E O   1 
ATOM   5828 C CB  . ARG   D 4 191 ? 126.216 111.216 88.994  1.00 63.42  ? 179 ARG   E CB  1 
ATOM   5829 C CG  . ARG   D 4 191 ? 126.704 111.060 90.420  1.00 63.42  ? 179 ARG   E CG  1 
ATOM   5830 C CD  . ARG   D 4 191 ? 126.508 112.321 91.217  1.00 63.42  ? 179 ARG   E CD  1 
ATOM   5831 N NE  . ARG   D 4 191 ? 127.685 112.624 92.016  1.00 63.42  ? 179 ARG   E NE  1 
ATOM   5832 C CZ  . ARG   D 4 191 ? 128.574 113.558 91.704  1.00 63.42  ? 179 ARG   E CZ  1 
ATOM   5833 N NH1 . ARG   D 4 191 ? 128.419 114.284 90.609  1.00 63.42  ? 179 ARG   E NH1 1 
ATOM   5834 N NH2 . ARG   D 4 191 ? 129.620 113.765 92.489  1.00 63.42  ? 179 ARG   E NH2 1 
ATOM   5835 N N   . MET   D 4 192 ? 125.839 109.035 86.011  1.00 67.30  ? 180 MET   E N   1 
ATOM   5836 C CA  . MET   D 4 192 ? 124.965 108.509 84.964  1.00 67.30  ? 180 MET   E CA  1 
ATOM   5837 C C   . MET   D 4 192 ? 124.601 109.532 83.895  1.00 67.30  ? 180 MET   E C   1 
ATOM   5838 O O   . MET   D 4 192 ? 124.108 109.165 82.825  1.00 67.30  ? 180 MET   E O   1 
ATOM   5839 C CB  . MET   D 4 192 ? 123.685 107.956 85.596  1.00 67.30  ? 180 MET   E CB  1 
ATOM   5840 C CG  . MET   D 4 192 ? 122.710 107.326 84.630  1.00 67.30  ? 180 MET   E CG  1 
ATOM   5841 S SD  . MET   D 4 192 ? 121.241 106.683 85.435  1.00 67.30  ? 180 MET   E SD  1 
ATOM   5842 C CE  . MET   D 4 192 ? 120.404 108.206 85.866  1.00 67.30  ? 180 MET   E CE  1 
ATOM   5843 N N   . SER   D 4 193 ? 124.888 110.807 84.129  1.00 65.76  ? 181 SER   E N   1 
ATOM   5844 C CA  . SER   D 4 193 ? 124.467 111.816 83.166  1.00 65.76  ? 181 SER   E CA  1 
ATOM   5845 C C   . SER   D 4 193 ? 125.463 112.938 82.930  1.00 65.76  ? 181 SER   E C   1 
ATOM   5846 O O   . SER   D 4 193 ? 125.293 113.676 81.957  1.00 65.76  ? 181 SER   E O   1 
ATOM   5847 C CB  . SER   D 4 193 ? 123.130 112.427 83.599  1.00 65.76  ? 181 SER   E CB  1 
ATOM   5848 O OG  . SER   D 4 193 ? 123.221 112.975 84.899  1.00 65.76  ? 181 SER   E OG  1 
ATOM   5849 N N   . ASN   D 4 194 ? 126.486 113.096 83.759  1.00 61.54  ? 182 ASN   E N   1 
ATOM   5850 C CA  . ASN   D 4 194 ? 127.310 114.293 83.763  1.00 61.54  ? 182 ASN   E CA  1 
ATOM   5851 C C   . ASN   D 4 194 ? 128.631 114.021 83.064  1.00 61.54  ? 182 ASN   E C   1 
ATOM   5852 O O   . ASN   D 4 194 ? 129.332 113.064 83.403  1.00 61.54  ? 182 ASN   E O   1 
ATOM   5853 C CB  . ASN   D 4 194 ? 127.551 114.748 85.196  1.00 61.54  ? 182 ASN   E CB  1 
ATOM   5854 C CG  . ASN   D 4 194 ? 126.275 115.106 85.903  1.00 61.54  ? 182 ASN   E CG  1 
ATOM   5855 O OD1 . ASN   D 4 194 ? 125.883 114.449 86.862  1.00 61.54  ? 182 ASN   E OD1 1 
ATOM   5856 N ND2 . ASN   D 4 194 ? 125.606 116.147 85.427  1.00 61.54  ? 182 ASN   E ND2 1 
ATOM   5857 N N   . LEU   D 4 195 ? 128.968 114.863 82.097  1.00 62.70  ? 183 LEU   E N   1 
ATOM   5858 C CA  . LEU   D 4 195 ? 130.201 114.722 81.343  1.00 62.70  ? 183 LEU   E CA  1 
ATOM   5859 C C   . LEU   D 4 195 ? 131.355 115.360 82.098  1.00 62.70  ? 183 LEU   E C   1 
ATOM   5860 O O   . LEU   D 4 195 ? 131.194 116.401 82.739  1.00 62.70  ? 183 LEU   E O   1 
ATOM   5861 C CB  . LEU   D 4 195 ? 130.073 115.363 79.962  1.00 62.70  ? 183 LEU   E CB  1 
ATOM   5862 C CG  . LEU   D 4 195 ? 129.424 114.562 78.840  1.00 62.70  ? 183 LEU   E CG  1 
ATOM   5863 C CD1 . LEU   D 4 195 ? 130.267 113.342 78.535  1.00 62.70  ? 183 LEU   E CD1 1 
ATOM   5864 C CD2 . LEU   D 4 195 ? 127.989 114.173 79.158  1.00 62.70  ? 183 LEU   E CD2 1 
ATOM   5865 N N   . ALA   D 4 196 ? 132.520 114.731 82.014  1.00 66.88  ? 184 ALA   E N   1 
ATOM   5866 C CA  . ALA   D 4 196 ? 133.695 115.229 82.702  1.00 66.88  ? 184 ALA   E CA  1 
ATOM   5867 C C   . ALA   D 4 196 ? 134.386 116.299 81.868  1.00 66.88  ? 184 ALA   E C   1 
ATOM   5868 O O   . ALA   D 4 196 ? 134.150 116.439 80.665  1.00 66.88  ? 184 ALA   E O   1 
ATOM   5869 C CB  . ALA   D 4 196 ? 134.664 114.091 83.000  1.00 66.88  ? 184 ALA   E CB  1 
ATOM   5870 N N   . SER   D 4 197 ? 135.246 117.068 82.529  1.00 74.20  ? 185 SER   E N   1 
ATOM   5871 C CA  . SER   D 4 197 ? 136.001 118.102 81.840  1.00 74.20  ? 185 SER   E CA  1 
ATOM   5872 C C   . SER   D 4 197 ? 136.989 117.474 80.869  1.00 74.20  ? 185 SER   E C   1 
ATOM   5873 O O   . SER   D 4 197 ? 137.680 116.506 81.198  1.00 74.20  ? 185 SER   E O   1 
ATOM   5874 C CB  . SER   D 4 197 ? 136.738 118.984 82.847  1.00 74.20  ? 185 SER   E CB  1 
ATOM   5875 O OG  . SER   D 4 197 ? 137.533 119.955 82.189  1.00 74.20  ? 185 SER   E OG  1 
ATOM   5876 N N   . GLY   D 4 198 ? 137.056 118.032 79.665  1.00 75.51  ? 186 GLY   E N   1 
ATOM   5877 C CA  . GLY   D 4 198 ? 137.930 117.516 78.637  1.00 75.51  ? 186 GLY   E CA  1 
ATOM   5878 C C   . GLY   D 4 198 ? 137.338 116.417 77.788  1.00 75.51  ? 186 GLY   E C   1 
ATOM   5879 O O   . GLY   D 4 198 ? 137.991 115.973 76.836  1.00 75.51  ? 186 GLY   E O   1 
ATOM   5880 N N   . VAL   D 4 199 ? 136.131 115.961 78.097  1.00 73.85  ? 187 VAL   E N   1 
ATOM   5881 C CA  . VAL   D 4 199 ? 135.464 114.944 77.293  1.00 73.85  ? 187 VAL   E CA  1 
ATOM   5882 C C   . VAL   D 4 199 ? 134.586 115.642 76.261  1.00 73.85  ? 187 VAL   E C   1 
ATOM   5883 O O   . VAL   D 4 199 ? 133.815 116.544 76.619  1.00 73.85  ? 187 VAL   E O   1 
ATOM   5884 C CB  . VAL   D 4 199 ? 134.651 113.986 78.174  1.00 73.85  ? 187 VAL   E CB  1 
ATOM   5885 C CG1 . VAL   D 4 199 ? 133.724 113.137 77.324  1.00 73.85  ? 187 VAL   E CG1 1 
ATOM   5886 C CG2 . VAL   D 4 199 ? 135.582 113.104 78.984  1.00 73.85  ? 187 VAL   E CG2 1 
ATOM   5887 N N   . PRO   D 4 200 ? 134.678 115.280 74.980  1.00 75.87  ? 188 PRO   E N   1 
ATOM   5888 C CA  . PRO   D 4 200 ? 133.810 115.901 73.977  1.00 75.87  ? 188 PRO   E CA  1 
ATOM   5889 C C   . PRO   D 4 200 ? 132.345 115.626 74.271  1.00 75.87  ? 188 PRO   E C   1 
ATOM   5890 O O   . PRO   D 4 200 ? 131.985 114.604 74.858  1.00 75.87  ? 188 PRO   E O   1 
ATOM   5891 C CB  . PRO   D 4 200 ? 134.252 115.242 72.665  1.00 75.87  ? 188 PRO   E CB  1 
ATOM   5892 C CG  . PRO   D 4 200 ? 135.621 114.719 72.943  1.00 75.87  ? 188 PRO   E CG  1 
ATOM   5893 C CD  . PRO   D 4 200 ? 135.611 114.316 74.379  1.00 75.87  ? 188 PRO   E CD  1 
ATOM   5894 N N   . ASP   D 4 201 ? 131.494 116.564 73.857  1.00 80.91  ? 189 ASP   E N   1 
ATOM   5895 C CA  . ASP   D 4 201 ? 130.072 116.501 74.161  1.00 80.91  ? 189 ASP   E CA  1 
ATOM   5896 C C   . ASP   D 4 201 ? 129.368 115.325 73.499  1.00 80.91  ? 189 ASP   E C   1 
ATOM   5897 O O   . ASP   D 4 201 ? 128.230 115.023 73.872  1.00 80.91  ? 189 ASP   E O   1 
ATOM   5898 C CB  . ASP   D 4 201 ? 129.392 117.805 73.742  1.00 80.91  ? 189 ASP   E CB  1 
ATOM   5899 C CG  . ASP   D 4 201 ? 128.356 118.271 74.746  1.00 80.91  ? 189 ASP   E CG  1 
ATOM   5900 O OD1 . ASP   D 4 201 ? 127.860 117.429 75.525  1.00 80.91  ? 189 ASP   E OD1 1 
ATOM   5901 O OD2 . ASP   D 4 201 ? 128.037 119.478 74.756  1.00 80.91  ? 189 ASP   E OD2 1 
ATOM   5902 N N   . ARG   D 4 202 ? 130.006 114.659 72.536  1.00 78.04  ? 190 ARG   E N   1 
ATOM   5903 C CA  . ARG   D 4 202 ? 129.361 113.570 71.814  1.00 78.04  ? 190 ARG   E CA  1 
ATOM   5904 C C   . ARG   D 4 202 ? 129.092 112.349 72.678  1.00 78.04  ? 190 ARG   E C   1 
ATOM   5905 O O   . ARG   D 4 202 ? 128.345 111.466 72.247  1.00 78.04  ? 190 ARG   E O   1 
ATOM   5906 C CB  . ARG   D 4 202 ? 130.206 113.161 70.614  1.00 78.04  ? 190 ARG   E CB  1 
ATOM   5907 C CG  . ARG   D 4 202 ? 131.677 113.085 70.906  1.00 78.04  ? 190 ARG   E CG  1 
ATOM   5908 C CD  . ARG   D 4 202 ? 132.475 113.025 69.625  1.00 78.04  ? 190 ARG   E CD  1 
ATOM   5909 N NE  . ARG   D 4 202 ? 133.901 113.172 69.876  1.00 78.04  ? 190 ARG   E NE  1 
ATOM   5910 C CZ  . ARG   D 4 202 ? 134.667 112.210 70.372  1.00 78.04  ? 190 ARG   E CZ  1 
ATOM   5911 N NH1 . ARG   D 4 202 ? 134.140 111.033 70.666  1.00 78.04  ? 190 ARG   E NH1 1 
ATOM   5912 N NH2 . ARG   D 4 202 ? 135.957 112.423 70.570  1.00 78.04  ? 190 ARG   E NH2 1 
ATOM   5913 N N   . PHE   D 4 203 ? 129.680 112.264 73.866  1.00 71.61  ? 191 PHE   E N   1 
ATOM   5914 C CA  . PHE   D 4 203 ? 129.376 111.192 74.800  1.00 71.61  ? 191 PHE   E CA  1 
ATOM   5915 C C   . PHE   D 4 203 ? 128.151 111.575 75.614  1.00 71.61  ? 191 PHE   E C   1 
ATOM   5916 O O   . PHE   D 4 203 ? 128.104 112.658 76.205  1.00 71.61  ? 191 PHE   E O   1 
ATOM   5917 C CB  . PHE   D 4 203 ? 130.559 110.920 75.728  1.00 71.61  ? 191 PHE   E CB  1 
ATOM   5918 C CG  . PHE   D 4 203 ? 131.740 110.309 75.041  1.00 71.61  ? 191 PHE   E CG  1 
ATOM   5919 C CD1 . PHE   D 4 203 ? 131.815 108.949 74.853  1.00 71.61  ? 191 PHE   E CD1 1 
ATOM   5920 C CD2 . PHE   D 4 203 ? 132.776 111.097 74.587  1.00 71.61  ? 191 PHE   E CD2 1 
ATOM   5921 C CE1 . PHE   D 4 203 ? 132.891 108.387 74.225  1.00 71.61  ? 191 PHE   E CE1 1 
ATOM   5922 C CE2 . PHE   D 4 203 ? 133.858 110.535 73.957  1.00 71.61  ? 191 PHE   E CE2 1 
ATOM   5923 C CZ  . PHE   D 4 203 ? 133.915 109.180 73.778  1.00 71.61  ? 191 PHE   E CZ  1 
ATOM   5924 N N   . SER   D 4 204 ? 127.159 110.694 75.635  1.00 68.82  ? 192 SER   E N   1 
ATOM   5925 C CA  . SER   D 4 204 ? 125.938 110.919 76.386  1.00 68.82  ? 192 SER   E CA  1 
ATOM   5926 C C   . SER   D 4 204 ? 125.598 109.665 77.169  1.00 68.82  ? 192 SER   E C   1 
ATOM   5927 O O   . SER   D 4 204 ? 125.907 108.549 76.749  1.00 68.82  ? 192 SER   E O   1 
ATOM   5928 C CB  . SER   D 4 204 ? 124.768 111.299 75.467  1.00 68.82  ? 192 SER   E CB  1 
ATOM   5929 O OG  . SER   D 4 204 ? 124.359 110.198 74.675  1.00 68.82  ? 192 SER   E OG  1 
ATOM   5930 N N   . GLY   D 4 205 ? 124.963 109.856 78.305  1.00 63.88  ? 193 GLY   E N   1 
ATOM   5931 C CA  . GLY   D 4 205 ? 124.643 108.751 79.189  1.00 63.88  ? 193 GLY   E CA  1 
ATOM   5932 C C   . GLY   D 4 205 ? 123.193 108.784 79.607  1.00 63.88  ? 193 GLY   E C   1 
ATOM   5933 O O   . GLY   D 4 205 ? 122.632 109.848 79.861  1.00 63.88  ? 193 GLY   E O   1 
ATOM   5934 N N   . SER   D 4 206 ? 122.593 107.602 79.681  1.00 65.73  ? 194 SER   E N   1 
ATOM   5935 C CA  . SER   D 4 206 ? 121.206 107.459 80.080  1.00 65.73  ? 194 SER   E CA  1 
ATOM   5936 C C   . SER   D 4 206 ? 121.081 106.228 80.960  1.00 65.73  ? 194 SER   E C   1 
ATOM   5937 O O   . SER   D 4 206 ? 122.063 105.538 81.244  1.00 65.73  ? 194 SER   E O   1 
ATOM   5938 C CB  . SER   D 4 206 ? 120.287 107.360 78.860  1.00 65.73  ? 194 SER   E CB  1 
ATOM   5939 O OG  . SER   D 4 206 ? 120.601 106.221 78.081  1.00 65.73  ? 194 SER   E OG  1 
ATOM   5940 N N   . GLY   D 4 207 ? 119.859 105.950 81.395  1.00 66.19  ? 195 GLY   E N   1 
ATOM   5941 C CA  . GLY   D 4 207 ? 119.601 104.735 82.132  1.00 66.19  ? 195 GLY   E CA  1 
ATOM   5942 C C   . GLY   D 4 207 ? 118.733 104.908 83.357  1.00 66.19  ? 195 GLY   E C   1 
ATOM   5943 O O   . GLY   D 4 207 ? 118.670 105.990 83.942  1.00 66.19  ? 195 GLY   E O   1 
ATOM   5944 N N   . SER   D 4 208 ? 118.048 103.841 83.740  1.00 69.70  ? 196 SER   E N   1 
ATOM   5945 C CA  . SER   D 4 208 ? 117.276 103.762 84.964  1.00 69.70  ? 196 SER   E CA  1 
ATOM   5946 C C   . SER   D 4 208 ? 118.032 102.898 85.965  1.00 69.70  ? 196 SER   E C   1 
ATOM   5947 O O   . SER   D 4 208 ? 119.188 102.520 85.742  1.00 69.70  ? 196 SER   E O   1 
ATOM   5948 C CB  . SER   D 4 208 ? 115.883 103.206 84.677  1.00 69.70  ? 196 SER   E CB  1 
ATOM   5949 O OG  . SER   D 4 208 ? 115.883 101.793 84.759  1.00 69.70  ? 196 SER   E OG  1 
ATOM   5950 N N   . GLY   D 4 209 ? 117.388 102.599 87.085  1.00 72.19  ? 197 GLY   E N   1 
ATOM   5951 C CA  . GLY   D 4 209 ? 117.943 101.628 88.005  1.00 72.19  ? 197 GLY   E CA  1 
ATOM   5952 C C   . GLY   D 4 209 ? 118.123 100.272 87.352  1.00 72.19  ? 197 GLY   E C   1 
ATOM   5953 O O   . GLY   D 4 209 ? 117.192 99.749  86.731  1.00 72.19  ? 197 GLY   E O   1 
ATOM   5954 N N   . THR   D 4 210 ? 119.324 99.704  87.478  1.00 69.69  ? 198 THR   E N   1 
ATOM   5955 C CA  . THR   D 4 210 ? 119.662 98.385  86.937  1.00 69.69  ? 198 THR   E CA  1 
ATOM   5956 C C   . THR   D 4 210 ? 119.522 98.318  85.419  1.00 69.69  ? 198 THR   E C   1 
ATOM   5957 O O   . THR   D 4 210 ? 119.248 97.253  84.864  1.00 69.69  ? 198 THR   E O   1 
ATOM   5958 C CB  . THR   D 4 210 ? 118.829 97.275  87.582  1.00 69.69  ? 198 THR   E CB  1 
ATOM   5959 O OG1 . THR   D 4 210 ? 117.469 97.373  87.141  1.00 69.69  ? 198 THR   E OG1 1 
ATOM   5960 C CG2 . THR   D 4 210 ? 118.877 97.377  89.091  1.00 69.69  ? 198 THR   E CG2 1 
ATOM   5961 N N   . ALA   D 4 211 ? 119.707 99.440  84.732  1.00 66.48  ? 199 ALA   E N   1 
ATOM   5962 C CA  . ALA   D 4 211 ? 119.757 99.444  83.273  1.00 66.48  ? 199 ALA   E CA  1 
ATOM   5963 C C   . ALA   D 4 211 ? 120.399 100.746 82.835  1.00 66.48  ? 199 ALA   E C   1 
ATOM   5964 O O   . ALA   D 4 211 ? 119.853 101.817 83.110  1.00 66.48  ? 199 ALA   E O   1 
ATOM   5965 C CB  . ALA   D 4 211 ? 118.361 99.299  82.669  1.00 66.48  ? 199 ALA   E CB  1 
ATOM   5966 N N   . PHE   D 4 212 ? 121.542 100.667 82.159  1.00 64.49  ? 200 PHE   E N   1 
ATOM   5967 C CA  . PHE   D 4 212 ? 122.293 101.859 81.794  1.00 64.49  ? 200 PHE   E CA  1 
ATOM   5968 C C   . PHE   D 4 212 ? 122.828 101.719 80.380  1.00 64.49  ? 200 PHE   E C   1 
ATOM   5969 O O   . PHE   D 4 212 ? 123.120 100.616 79.917  1.00 64.49  ? 200 PHE   E O   1 
ATOM   5970 C CB  . PHE   D 4 212 ? 123.451 102.110 82.754  1.00 64.49  ? 200 PHE   E CB  1 
ATOM   5971 C CG  . PHE   D 4 212 ? 123.056 102.098 84.190  1.00 64.49  ? 200 PHE   E CG  1 
ATOM   5972 C CD1 . PHE   D 4 212 ? 122.647 103.252 84.807  1.00 64.49  ? 200 PHE   E CD1 1 
ATOM   5973 C CD2 . PHE   D 4 212 ? 123.090 100.933 84.925  1.00 64.49  ? 200 PHE   E CD2 1 
ATOM   5974 C CE1 . PHE   D 4 212 ? 122.282 103.244 86.120  1.00 64.49  ? 200 PHE   E CE1 1 
ATOM   5975 C CE2 . PHE   D 4 212 ? 122.724 100.925 86.240  1.00 64.49  ? 200 PHE   E CE2 1 
ATOM   5976 C CZ  . PHE   D 4 212 ? 122.320 102.080 86.838  1.00 64.49  ? 200 PHE   E CZ  1 
ATOM   5977 N N   . THR   D 4 213 ? 122.953 102.852 79.697  1.00 65.28  ? 201 THR   E N   1 
ATOM   5978 C CA  . THR   D 4 213 ? 123.474 102.893 78.343  1.00 65.28  ? 201 THR   E CA  1 
ATOM   5979 C C   . THR   D 4 213 ? 124.438 104.057 78.214  1.00 65.28  ? 201 THR   E C   1 
ATOM   5980 O O   . THR   D 4 213 ? 124.202 105.130 78.772  1.00 65.28  ? 201 THR   E O   1 
ATOM   5981 C CB  . THR   D 4 213 ? 122.355 103.039 77.301  1.00 65.28  ? 201 THR   E CB  1 
ATOM   5982 O OG1 . THR   D 4 213 ? 121.687 104.294 77.486  1.00 65.28  ? 201 THR   E OG1 1 
ATOM   5983 C CG2 . THR   D 4 213 ? 121.343 101.909 77.422  1.00 65.28  ? 201 THR   E CG2 1 
ATOM   5984 N N   . LEU   D 4 214 ? 125.520 103.846 77.478  1.00 65.32  ? 202 LEU   E N   1 
ATOM   5985 C CA  . LEU   D 4 214 ? 126.458 104.909 77.145  1.00 65.32  ? 202 LEU   E CA  1 
ATOM   5986 C C   . LEU   D 4 214 ? 126.415 105.101 75.640  1.00 65.32  ? 202 LEU   E C   1 
ATOM   5987 O O   . LEU   D 4 214 ? 126.952 104.282 74.888  1.00 65.32  ? 202 LEU   E O   1 
ATOM   5988 C CB  . LEU   D 4 214 ? 127.874 104.584 77.609  1.00 65.32  ? 202 LEU   E CB  1 
ATOM   5989 C CG  . LEU   D 4 214 ? 128.907 105.664 77.288  1.00 65.32  ? 202 LEU   E CG  1 
ATOM   5990 C CD1 . LEU   D 4 214 ? 128.720 106.867 78.180  1.00 65.32  ? 202 LEU   E CD1 1 
ATOM   5991 C CD2 . LEU   D 4 214 ? 130.294 105.125 77.440  1.00 65.32  ? 202 LEU   E CD2 1 
ATOM   5992 N N   . THR   D 4 215 ? 125.780 106.179 75.205  1.00 70.35  ? 203 THR   E N   1 
ATOM   5993 C CA  . THR   D 4 215 ? 125.602 106.452 73.789  1.00 70.35  ? 203 THR   E CA  1 
ATOM   5994 C C   . THR   D 4 215 ? 126.720 107.360 73.297  1.00 70.35  ? 203 THR   E C   1 
ATOM   5995 O O   . THR   D 4 215 ? 126.919 108.456 73.832  1.00 70.35  ? 203 THR   E O   1 
ATOM   5996 C CB  . THR   D 4 215 ? 124.240 107.094 73.541  1.00 70.35  ? 203 THR   E CB  1 
ATOM   5997 O OG1 . THR   D 4 215 ? 123.207 106.204 73.977  1.00 70.35  ? 203 THR   E OG1 1 
ATOM   5998 C CG2 . THR   D 4 215 ? 124.054 107.398 72.062  1.00 70.35  ? 203 THR   E CG2 1 
ATOM   5999 N N   . ILE   D 4 216 ? 127.443 106.906 72.291  1.00 74.80  ? 204 ILE   E N   1 
ATOM   6000 C CA  . ILE   D 4 216 ? 128.389 107.732 71.558  1.00 74.80  ? 204 ILE   E CA  1 
ATOM   6001 C C   . ILE   D 4 216 ? 127.709 108.213 70.289  1.00 74.80  ? 204 ILE   E C   1 
ATOM   6002 O O   . ILE   D 4 216 ? 126.937 107.474 69.666  1.00 74.80  ? 204 ILE   E O   1 
ATOM   6003 C CB  . ILE   D 4 216 ? 129.677 106.958 71.226  1.00 74.80  ? 204 ILE   E CB  1 
ATOM   6004 C CG1 . ILE   D 4 216 ? 130.224 106.264 72.469  1.00 74.80  ? 204 ILE   E CG1 1 
ATOM   6005 C CG2 . ILE   D 4 216 ? 130.718 107.880 70.631  1.00 74.80  ? 204 ILE   E CG2 1 
ATOM   6006 C CD1 . ILE   D 4 216 ? 131.248 105.210 72.160  1.00 74.80  ? 204 ILE   E CD1 1 
ATOM   6007 N N   . SER   D 4 217 ? 127.981 109.453 69.908  1.00 81.79  ? 205 SER   E N   1 
ATOM   6008 C CA  . SER   D 4 217 ? 127.536 110.000 68.637  1.00 81.79  ? 205 SER   E CA  1 
ATOM   6009 C C   . SER   D 4 217 ? 128.756 110.273 67.772  1.00 81.79  ? 205 SER   E C   1 
ATOM   6010 O O   . SER   D 4 217 ? 129.711 110.910 68.228  1.00 81.79  ? 205 SER   E O   1 
ATOM   6011 C CB  . SER   D 4 217 ? 126.724 111.280 68.841  1.00 81.79  ? 205 SER   E CB  1 
ATOM   6012 O OG  . SER   D 4 217 ? 125.467 110.997 69.430  1.00 81.79  ? 205 SER   E OG  1 
ATOM   6013 N N   . ARG   D 4 218 ? 128.723 109.788 66.532  1.00 83.16  ? 206 ARG   E N   1 
ATOM   6014 C CA  . ARG   D 4 218 ? 129.814 109.978 65.580  1.00 83.16  ? 206 ARG   E CA  1 
ATOM   6015 C C   . ARG   D 4 218 ? 131.126 109.427 66.143  1.00 83.16  ? 206 ARG   E C   1 
ATOM   6016 O O   . ARG   D 4 218 ? 132.073 110.163 66.426  1.00 83.16  ? 206 ARG   E O   1 
ATOM   6017 C CB  . ARG   D 4 218 ? 129.951 111.453 65.188  1.00 83.16  ? 206 ARG   E CB  1 
ATOM   6018 N N   . LEU   D 4 219 ? 131.160 108.107 66.307  1.00 82.82  ? 207 LEU   E N   1 
ATOM   6019 C CA  . LEU   D 4 219 ? 132.304 107.437 66.922  1.00 82.82  ? 207 LEU   E CA  1 
ATOM   6020 C C   . LEU   D 4 219 ? 133.507 107.559 66.000  1.00 82.82  ? 207 LEU   E C   1 
ATOM   6021 O O   . LEU   D 4 219 ? 133.628 106.834 65.012  1.00 82.82  ? 207 LEU   E O   1 
ATOM   6022 C CB  . LEU   D 4 219 ? 131.978 105.976 67.205  1.00 82.82  ? 207 LEU   E CB  1 
ATOM   6023 C CG  . LEU   D 4 219 ? 133.099 105.166 67.851  1.00 82.82  ? 207 LEU   E CG  1 
ATOM   6024 C CD1 . LEU   D 4 219 ? 133.647 105.895 69.065  1.00 82.82  ? 207 LEU   E CD1 1 
ATOM   6025 C CD2 . LEU   D 4 219 ? 132.593 103.800 68.249  1.00 82.82  ? 207 LEU   E CD2 1 
ATOM   6026 N N   . GLU   D 4 220 ? 134.407 108.475 66.332  1.00 81.88  ? 208 GLU   E N   1 
ATOM   6027 C CA  . GLU   D 4 220 ? 135.601 108.730 65.550  1.00 81.88  ? 208 GLU   E CA  1 
ATOM   6028 C C   . GLU   D 4 220 ? 136.805 108.066 66.208  1.00 81.88  ? 208 GLU   E C   1 
ATOM   6029 O O   . GLU   D 4 220 ? 136.699 107.411 67.247  1.00 81.88  ? 208 GLU   E O   1 
ATOM   6030 C CB  . GLU   D 4 220 ? 135.818 110.236 65.389  1.00 81.88  ? 208 GLU   E CB  1 
ATOM   6031 N N   . ALA   D 4 221 ? 137.969 108.240 65.589  1.00 84.02  ? 209 ALA   E N   1 
ATOM   6032 C CA  . ALA   D 4 221 ? 139.199 107.704 66.142  1.00 84.02  ? 209 ALA   E CA  1 
ATOM   6033 C C   . ALA   D 4 221 ? 139.519 108.379 67.475  1.00 84.02  ? 209 ALA   E C   1 
ATOM   6034 O O   . ALA   D 4 221 ? 138.907 109.376 67.865  1.00 84.02  ? 209 ALA   E O   1 
ATOM   6035 C CB  . ALA   D 4 221 ? 140.354 107.890 65.160  1.00 84.02  ? 209 ALA   E CB  1 
ATOM   6036 N N   . GLU   D 4 222 ? 140.496 107.807 68.180  1.00 81.05  ? 210 GLU   E N   1 
ATOM   6037 C CA  . GLU   D 4 222 ? 140.898 108.240 69.518  1.00 81.05  ? 210 GLU   E CA  1 
ATOM   6038 C C   . GLU   D 4 222 ? 139.763 108.114 70.528  1.00 81.05  ? 210 GLU   E C   1 
ATOM   6039 O O   . GLU   D 4 222 ? 139.815 108.715 71.606  1.00 81.05  ? 210 GLU   E O   1 
ATOM   6040 C CB  . GLU   D 4 222 ? 141.442 109.674 69.508  1.00 81.05  ? 210 GLU   E CB  1 
ATOM   6041 N N   . ASP   D 4 223 ? 138.732 107.337 70.193  1.00 78.14  ? 211 ASP   E N   1 
ATOM   6042 C CA  . ASP   D 4 223 ? 137.637 107.039 71.105  1.00 78.14  ? 211 ASP   E CA  1 
ATOM   6043 C C   . ASP   D 4 223 ? 137.426 105.540 71.246  1.00 78.14  ? 211 ASP   E C   1 
ATOM   6044 O O   . ASP   D 4 223 ? 136.406 105.117 71.798  1.00 78.14  ? 211 ASP   E O   1 
ATOM   6045 C CB  . ASP   D 4 223 ? 136.347 107.702 70.628  1.00 78.14  ? 211 ASP   E CB  1 
ATOM   6046 C CG  . ASP   D 4 223 ? 136.516 109.183 70.385  1.00 78.14  ? 211 ASP   E CG  1 
ATOM   6047 O OD1 . ASP   D 4 223 ? 137.246 109.835 71.160  1.00 78.14  ? 211 ASP   E OD1 1 
ATOM   6048 O OD2 . ASP   D 4 223 ? 135.929 109.693 69.409  1.00 78.14  ? 211 ASP   E OD2 1 
ATOM   6049 N N   . VAL   D 4 224 ? 138.347 104.743 70.750  1.00 72.08  ? 212 VAL   E N   1 
ATOM   6050 C CA  . VAL   D 4 224 ? 138.267 103.293 70.812  1.00 72.08  ? 212 VAL   E CA  1 
ATOM   6051 C C   . VAL   D 4 224 ? 139.040 102.812 72.027  1.00 72.08  ? 212 VAL   E C   1 
ATOM   6052 O O   . VAL   D 4 224 ? 140.053 103.395 72.426  1.00 72.08  ? 212 VAL   E O   1 
ATOM   6053 C CB  . VAL   D 4 224 ? 138.796 102.653 69.513  1.00 72.08  ? 212 VAL   E CB  1 
ATOM   6054 C CG1 . VAL   D 4 224 ? 137.994 103.142 68.321  1.00 72.08  ? 212 VAL   E CG1 1 
ATOM   6055 C CG2 . VAL   D 4 224 ? 140.266 102.960 69.326  1.00 72.08  ? 212 VAL   E CG2 1 
ATOM   6056 N N   . GLY   D 4 225 ? 138.548 101.745 72.627  1.00 65.81  ? 213 GLY   E N   1 
ATOM   6057 C CA  . GLY   D 4 225 ? 139.141 101.227 73.840  1.00 65.81  ? 213 GLY   E CA  1 
ATOM   6058 C C   . GLY   D 4 225 ? 138.138 100.366 74.575  1.00 65.81  ? 213 GLY   E C   1 
ATOM   6059 O O   . GLY   D 4 225 ? 137.240 99.785  73.968  1.00 65.81  ? 213 GLY   E O   1 
ATOM   6060 N N   . VAL   D 4 226 ? 138.302 100.311 75.888  1.00 59.88  ? 214 VAL   E N   1 
ATOM   6061 C CA  . VAL   D 4 226 ? 137.502 99.447  76.738  1.00 59.88  ? 214 VAL   E CA  1 
ATOM   6062 C C   . VAL   D 4 226 ? 136.775 100.324 77.743  1.00 59.88  ? 214 VAL   E C   1 
ATOM   6063 O O   . VAL   D 4 226 ? 137.402 101.130 78.437  1.00 59.88  ? 214 VAL   E O   1 
ATOM   6064 C CB  . VAL   D 4 226 ? 138.374 98.396  77.440  1.00 59.88  ? 214 VAL   E CB  1 
ATOM   6065 C CG1 . VAL   D 4 226 ? 137.542 97.572  78.385  1.00 59.88  ? 214 VAL   E CG1 1 
ATOM   6066 C CG2 . VAL   D 4 226 ? 139.060 97.522  76.424  1.00 59.88  ? 214 VAL   E CG2 1 
ATOM   6067 N N   . TYR   D 4 227 ? 135.459 100.172 77.815  1.00 61.37  ? 215 TYR   E N   1 
ATOM   6068 C CA  . TYR   D 4 227 ? 134.599 101.049 78.591  1.00 61.37  ? 215 TYR   E CA  1 
ATOM   6069 C C   . TYR   D 4 227 ? 134.120 100.320 79.833  1.00 61.37  ? 215 TYR   E C   1 
ATOM   6070 O O   . TYR   D 4 227 ? 133.551 99.229  79.736  1.00 61.37  ? 215 TYR   E O   1 
ATOM   6071 C CB  . TYR   D 4 227 ? 133.407 101.520 77.758  1.00 61.37  ? 215 TYR   E CB  1 
ATOM   6072 C CG  . TYR   D 4 227 ? 133.781 102.507 76.684  1.00 61.37  ? 215 TYR   E CG  1 
ATOM   6073 C CD1 . TYR   D 4 227 ? 134.640 102.155 75.668  1.00 61.37  ? 215 TYR   E CD1 1 
ATOM   6074 C CD2 . TYR   D 4 227 ? 133.289 103.789 76.699  1.00 61.37  ? 215 TYR   E CD2 1 
ATOM   6075 C CE1 . TYR   D 4 227 ? 134.990 103.042 74.700  1.00 61.37  ? 215 TYR   E CE1 1 
ATOM   6076 C CE2 . TYR   D 4 227 ? 133.634 104.688 75.729  1.00 61.37  ? 215 TYR   E CE2 1 
ATOM   6077 C CZ  . TYR   D 4 227 ? 134.490 104.309 74.732  1.00 61.37  ? 215 TYR   E CZ  1 
ATOM   6078 O OH  . TYR   D 4 227 ? 134.842 105.204 73.757  1.00 61.37  ? 215 TYR   E OH  1 
ATOM   6079 N N   . TYR   D 4 228 ? 134.347 100.924 80.992  1.00 57.30  ? 216 TYR   E N   1 
ATOM   6080 C CA  . TYR   D 4 228 ? 134.073 100.293 82.270  1.00 57.30  ? 216 TYR   E CA  1 
ATOM   6081 C C   . TYR   D 4 228 ? 132.969 101.033 83.003  1.00 57.30  ? 216 TYR   E C   1 
ATOM   6082 O O   . TYR   D 4 228 ? 132.963 102.265 83.058  1.00 57.30  ? 216 TYR   E O   1 
ATOM   6083 C CB  . TYR   D 4 228 ? 135.321 100.253 83.142  1.00 57.30  ? 216 TYR   E CB  1 
ATOM   6084 C CG  . TYR   D 4 228 ? 136.394 99.354  82.610  1.00 57.30  ? 216 TYR   E CG  1 
ATOM   6085 C CD1 . TYR   D 4 228 ? 137.402 99.853  81.817  1.00 57.30  ? 216 TYR   E CD1 1 
ATOM   6086 C CD2 . TYR   D 4 228 ? 136.398 98.009  82.899  1.00 57.30  ? 216 TYR   E CD2 1 
ATOM   6087 C CE1 . TYR   D 4 228 ? 138.382 99.039  81.329  1.00 57.30  ? 216 TYR   E CE1 1 
ATOM   6088 C CE2 . TYR   D 4 228 ? 137.372 97.183  82.411  1.00 57.30  ? 216 TYR   E CE2 1 
ATOM   6089 C CZ  . TYR   D 4 228 ? 138.363 97.702  81.626  1.00 57.30  ? 216 TYR   E CZ  1 
ATOM   6090 O OH  . TYR   D 4 228 ? 139.347 96.889  81.127  1.00 57.30  ? 216 TYR   E OH  1 
ATOM   6091 N N   . CYS   D 4 229 ? 132.041 100.273 83.563  1.00 61.02  ? 217 CYS   E N   1 
ATOM   6092 C CA  . CYS   D 4 229 ? 130.978 100.809 84.396  1.00 61.02  ? 217 CYS   E CA  1 
ATOM   6093 C C   . CYS   D 4 229 ? 131.231 100.337 85.815  1.00 61.02  ? 217 CYS   E C   1 
ATOM   6094 O O   . CYS   D 4 229 ? 131.276 99.131  86.076  1.00 61.02  ? 217 CYS   E O   1 
ATOM   6095 C CB  . CYS   D 4 229 ? 129.598 100.378 83.898  1.00 61.02  ? 217 CYS   E CB  1 
ATOM   6096 S SG  . CYS   D 4 229 ? 129.276 98.604  83.830  1.00 61.02  ? 217 CYS   E SG  1 
ATOM   6097 N N   . MET   D 4 230 ? 131.416 101.279 86.727  1.00 58.71  ? 218 MET   E N   1 
ATOM   6098 C CA  . MET   D 4 230 ? 131.555 100.949 88.128  1.00 58.71  ? 218 MET   E CA  1 
ATOM   6099 C C   . MET   D 4 230 ? 130.456 101.611 88.939  1.00 58.71  ? 218 MET   E C   1 
ATOM   6100 O O   . MET   D 4 230 ? 129.815 102.565 88.501  1.00 58.71  ? 218 MET   E O   1 
ATOM   6101 C CB  . MET   D 4 230 ? 132.915 101.359 88.683  1.00 58.71  ? 218 MET   E CB  1 
ATOM   6102 C CG  . MET   D 4 230 ? 133.125 102.841 88.771  1.00 58.71  ? 218 MET   E CG  1 
ATOM   6103 S SD  . MET   D 4 230 ? 134.556 103.198 89.793  1.00 58.71  ? 218 MET   E SD  1 
ATOM   6104 C CE  . MET   D 4 230 ? 133.855 102.879 91.393  1.00 58.71  ? 218 MET   E CE  1 
ATOM   6105 N N   . GLN   D 4 231 ? 130.263 101.089 90.140  1.00 59.10  ? 219 GLN   E N   1 
ATOM   6106 C CA  . GLN   D 4 231 ? 129.288 101.594 91.086  1.00 59.10  ? 219 GLN   E CA  1 
ATOM   6107 C C   . GLN   D 4 231 ? 129.997 102.246 92.258  1.00 59.10  ? 219 GLN   E C   1 
ATOM   6108 O O   . GLN   D 4 231 ? 131.048 101.775 92.699  1.00 59.10  ? 219 GLN   E O   1 
ATOM   6109 C CB  . GLN   D 4 231 ? 128.387 100.472 91.591  1.00 59.10  ? 219 GLN   E CB  1 
ATOM   6110 C CG  . GLN   D 4 231 ? 129.115 99.344  92.268  1.00 59.10  ? 219 GLN   E CG  1 
ATOM   6111 C CD  . GLN   D 4 231 ? 129.013 99.417  93.766  1.00 59.10  ? 219 GLN   E CD  1 
ATOM   6112 O OE1 . GLN   D 4 231 ? 128.170 100.128 94.305  1.00 59.10  ? 219 GLN   E OE1 1 
ATOM   6113 N NE2 . GLN   D 4 231 ? 129.860 98.669  94.453  1.00 59.10  ? 219 GLN   E NE2 1 
ATOM   6114 N N   . HIS   D 4 232 ? 129.422 103.329 92.757  1.00 58.70  ? 220 HIS   E N   1 
ATOM   6115 C CA  . HIS   D 4 232 ? 129.933 103.981 93.951  1.00 58.70  ? 220 HIS   E CA  1 
ATOM   6116 C C   . HIS   D 4 232 ? 128.883 104.030 95.051  1.00 58.70  ? 220 HIS   E C   1 
ATOM   6117 O O   . HIS   D 4 232 ? 128.895 104.936 95.883  1.00 58.70  ? 220 HIS   E O   1 
ATOM   6118 C CB  . HIS   D 4 232 ? 130.440 105.384 93.639  1.00 58.70  ? 220 HIS   E CB  1 
ATOM   6119 C CG  . HIS   D 4 232 ? 131.573 105.819 94.512  1.00 58.70  ? 220 HIS   E CG  1 
ATOM   6120 N ND1 . HIS   D 4 232 ? 131.483 105.852 95.885  1.00 58.70  ? 220 HIS   E ND1 1 
ATOM   6121 C CD2 . HIS   D 4 232 ? 132.821 106.240 94.207  1.00 58.70  ? 220 HIS   E CD2 1 
ATOM   6122 C CE1 . HIS   D 4 232 ? 132.626 106.274 96.389  1.00 58.70  ? 220 HIS   E CE1 1 
ATOM   6123 N NE2 . HIS   D 4 232 ? 133.457 106.513 95.392  1.00 58.70  ? 220 HIS   E NE2 1 
ATOM   6124 N N   . LEU   D 4 233 ? 127.960 103.069 95.064  1.00 60.38  ? 221 LEU   E N   1 
ATOM   6125 C CA  . LEU   D 4 233 ? 127.037 102.960 96.187  1.00 60.38  ? 221 LEU   E CA  1 
ATOM   6126 C C   . LEU   D 4 233 ? 127.755 102.498 97.443  1.00 60.38  ? 221 LEU   E C   1 
ATOM   6127 O O   . LEU   D 4 233 ? 127.838 103.230 98.435  1.00 60.38  ? 221 LEU   E O   1 
ATOM   6128 C CB  . LEU   D 4 233 ? 125.904 101.993 95.864  1.00 60.38  ? 221 LEU   E CB  1 
ATOM   6129 C CG  . LEU   D 4 233 ? 124.699 102.464 95.077  1.00 60.38  ? 221 LEU   E CG  1 
ATOM   6130 C CD1 . LEU   D 4 233 ? 123.838 101.278 94.763  1.00 60.38  ? 221 LEU   E CD1 1 
ATOM   6131 C CD2 . LEU   D 4 233 ? 123.944 103.450 95.922  1.00 60.38  ? 221 LEU   E CD2 1 
ATOM   6132 N N   . GLU   D 4 234 ? 128.286 101.281 97.416  1.00 61.15  ? 222 GLU   E N   1 
ATOM   6133 C CA  . GLU   D 4 234 ? 128.777 100.630 98.613  1.00 61.15  ? 222 GLU   E CA  1 
ATOM   6134 C C   . GLU   D 4 234 ? 130.122 99.994  98.329  1.00 61.15  ? 222 GLU   E C   1 
ATOM   6135 O O   . GLU   D 4 234 ? 130.419 99.611  97.196  1.00 61.15  ? 222 GLU   E O   1 
ATOM   6136 C CB  . GLU   D 4 234 ? 127.796 99.561  99.117  1.00 61.15  ? 222 GLU   E CB  1 
ATOM   6137 C CG  . GLU   D 4 234 ? 126.401 100.082 99.426  1.00 61.15  ? 222 GLU   E CG  1 
ATOM   6138 C CD  . GLU   D 4 234 ? 125.402 98.966  99.661  1.00 61.15  ? 222 GLU   E CD  1 
ATOM   6139 O OE1 . GLU   D 4 234 ? 125.755 97.790  99.429  1.00 61.15  ? 222 GLU   E OE1 1 
ATOM   6140 O OE2 . GLU   D 4 234 ? 124.262 99.265  100.075 1.00 61.15  ? 222 GLU   E OE2 1 
ATOM   6141 N N   . TYR   D 4 235 ? 130.925 99.877  99.370  1.00 55.83  ? 223 TYR   E N   1 
ATOM   6142 C CA  . TYR   D 4 235 ? 132.219 99.239  99.220  1.00 55.83  ? 223 TYR   E CA  1 
ATOM   6143 C C   . TYR   D 4 235 ? 132.084 97.730  99.398  1.00 55.83  ? 223 TYR   E C   1 
ATOM   6144 O O   . TYR   D 4 235 ? 131.338 97.276  100.268 1.00 55.83  ? 223 TYR   E O   1 
ATOM   6145 C CB  . TYR   D 4 235 ? 133.203 99.801  100.236 1.00 55.83  ? 223 TYR   E CB  1 
ATOM   6146 C CG  . TYR   D 4 235 ? 133.584 101.235 99.958  1.00 55.83  ? 223 TYR   E CG  1 
ATOM   6147 C CD1 . TYR   D 4 235 ? 134.626 101.541 99.099  1.00 55.83  ? 223 TYR   E CD1 1 
ATOM   6148 C CD2 . TYR   D 4 235 ? 132.899 102.282 100.548 1.00 55.83  ? 223 TYR   E CD2 1 
ATOM   6149 C CE1 . TYR   D 4 235 ? 134.978 102.844 98.841  1.00 55.83  ? 223 TYR   E CE1 1 
ATOM   6150 C CE2 . TYR   D 4 235 ? 133.248 103.589 100.296 1.00 55.83  ? 223 TYR   E CE2 1 
ATOM   6151 C CZ  . TYR   D 4 235 ? 134.288 103.861 99.440  1.00 55.83  ? 223 TYR   E CZ  1 
ATOM   6152 O OH  . TYR   D 4 235 ? 134.639 105.163 99.185  1.00 55.83  ? 223 TYR   E OH  1 
ATOM   6153 N N   . PRO   D 4 236 ? 132.787 96.908  98.603  1.00 58.30  ? 224 PRO   E N   1 
ATOM   6154 C CA  . PRO   D 4 236 ? 133.792 97.217  97.582  1.00 58.30  ? 224 PRO   E CA  1 
ATOM   6155 C C   . PRO   D 4 236 ? 133.245 97.767  96.276  1.00 58.30  ? 224 PRO   E C   1 
ATOM   6156 O O   . PRO   D 4 236 ? 132.189 97.340  95.824  1.00 58.30  ? 224 PRO   E O   1 
ATOM   6157 C CB  . PRO   D 4 236 ? 134.449 95.856  97.321  1.00 58.30  ? 224 PRO   E CB  1 
ATOM   6158 C CG  . PRO   D 4 236 ? 133.974 94.965  98.404  1.00 58.30  ? 224 PRO   E CG  1 
ATOM   6159 C CD  . PRO   D 4 236 ? 132.633 95.458  98.758  1.00 58.30  ? 224 PRO   E CD  1 
ATOM   6160 N N   . LEU   D 4 237 ? 133.979 98.695  95.673  1.00 55.98  ? 225 LEU   E N   1 
ATOM   6161 C CA  . LEU   D 4 237 ? 133.635 99.183  94.346  1.00 55.98  ? 225 LEU   E CA  1 
ATOM   6162 C C   . LEU   D 4 237 ? 133.851 98.079  93.323  1.00 55.98  ? 225 LEU   E C   1 
ATOM   6163 O O   . LEU   D 4 237 ? 134.886 97.408  93.331  1.00 55.98  ? 225 LEU   E O   1 
ATOM   6164 C CB  . LEU   D 4 237 ? 134.481 100.402 93.992  1.00 55.98  ? 225 LEU   E CB  1 
ATOM   6165 C CG  . LEU   D 4 237 ? 134.615 101.500 95.041  1.00 55.98  ? 225 LEU   E CG  1 
ATOM   6166 C CD1 . LEU   D 4 237 ? 135.499 102.604 94.518  1.00 55.98  ? 225 LEU   E CD1 1 
ATOM   6167 C CD2 . LEU   D 4 237 ? 133.265 102.037 95.418  1.00 55.98  ? 225 LEU   E CD2 1 
ATOM   6168 N N   . THR   D 4 238 ? 132.879 97.889  92.440  1.00 58.52  ? 226 THR   E N   1 
ATOM   6169 C CA  . THR   D 4 238 ? 132.884 96.780  91.501  1.00 58.52  ? 226 THR   E CA  1 
ATOM   6170 C C   . THR   D 4 238 ? 132.808 97.314  90.084  1.00 58.52  ? 226 THR   E C   1 
ATOM   6171 O O   . THR   D 4 238 ? 131.977 98.176  89.786  1.00 58.52  ? 226 THR   E O   1 
ATOM   6172 C CB  . THR   D 4 238 ? 131.721 95.825  91.774  1.00 58.52  ? 226 THR   E CB  1 
ATOM   6173 O OG1 . THR   D 4 238 ? 132.005 95.049  92.942  1.00 58.52  ? 226 THR   E OG1 1 
ATOM   6174 C CG2 . THR   D 4 238 ? 131.506 94.886  90.601  1.00 58.52  ? 226 THR   E CG2 1 
ATOM   6175 N N   . PHE   D 4 239 ? 133.667 96.800  89.219  1.00 57.18  ? 227 PHE   E N   1 
ATOM   6176 C CA  . PHE   D 4 239 ? 133.701 97.172  87.820  1.00 57.18  ? 227 PHE   E CA  1 
ATOM   6177 C C   . PHE   D 4 239 ? 133.002 96.105  86.982  1.00 57.18  ? 227 PHE   E C   1 
ATOM   6178 O O   . PHE   D 4 239 ? 132.387 95.171  87.502  1.00 57.18  ? 227 PHE   E O   1 
ATOM   6179 C CB  . PHE   D 4 239 ? 135.143 97.359  87.358  1.00 57.18  ? 227 PHE   E CB  1 
ATOM   6180 C CG  . PHE   D 4 239 ? 135.848 98.513  87.986  1.00 57.18  ? 227 PHE   E CG  1 
ATOM   6181 C CD1 . PHE   D 4 239 ? 136.175 99.618  87.238  1.00 57.18  ? 227 PHE   E CD1 1 
ATOM   6182 C CD2 . PHE   D 4 239 ? 136.241 98.474  89.306  1.00 57.18  ? 227 PHE   E CD2 1 
ATOM   6183 C CE1 . PHE   D 4 239 ? 136.841 100.667 87.801  1.00 57.18  ? 227 PHE   E CE1 1 
ATOM   6184 C CE2 . PHE   D 4 239 ? 136.912 99.531  89.869  1.00 57.18  ? 227 PHE   E CE2 1 
ATOM   6185 C CZ  . PHE   D 4 239 ? 137.209 100.621 89.117  1.00 57.18  ? 227 PHE   E CZ  1 
ATOM   6186 N N   . GLY   D 4 240 ? 133.095 96.245  85.661  1.00 59.74  ? 228 GLY   E N   1 
ATOM   6187 C CA  . GLY   D 4 240 ? 132.673 95.225  84.734  1.00 59.74  ? 228 GLY   E CA  1 
ATOM   6188 C C   . GLY   D 4 240 ? 133.830 94.787  83.855  1.00 59.74  ? 228 GLY   E C   1 
ATOM   6189 O O   . GLY   D 4 240 ? 134.929 95.343  83.904  1.00 59.74  ? 228 GLY   E O   1 
ATOM   6190 N N   . ALA   D 4 241 ? 133.558 93.770  83.042  1.00 61.84  ? 229 ALA   E N   1 
ATOM   6191 C CA  . ALA   D 4 241 ? 134.598 93.191  82.203  1.00 61.84  ? 229 ALA   E CA  1 
ATOM   6192 C C   . ALA   D 4 241 ? 135.016 94.100  81.060  1.00 61.84  ? 229 ALA   E C   1 
ATOM   6193 O O   . ALA   D 4 241 ? 136.031 93.824  80.414  1.00 61.84  ? 229 ALA   E O   1 
ATOM   6194 C CB  . ALA   D 4 241 ? 134.132 91.845  81.646  1.00 61.84  ? 229 ALA   E CB  1 
ATOM   6195 N N   . GLY   D 4 242 ? 134.273 95.159  80.789  1.00 63.20  ? 230 GLY   E N   1 
ATOM   6196 C CA  . GLY   D 4 242 ? 134.640 96.094  79.745  1.00 63.20  ? 230 GLY   E CA  1 
ATOM   6197 C C   . GLY   D 4 242 ? 133.950 95.793  78.431  1.00 63.20  ? 230 GLY   E C   1 
ATOM   6198 O O   . GLY   D 4 242 ? 133.183 94.838  78.287  1.00 63.20  ? 230 GLY   E O   1 
ATOM   6199 N N   . THR   D 4 243 ? 134.234 96.649  77.453  1.00 66.67  ? 231 THR   E N   1 
ATOM   6200 C CA  . THR   D 4 243 ? 133.626 96.527  76.133  1.00 66.67  ? 231 THR   E CA  1 
ATOM   6201 C C   . THR   D 4 243 ? 134.605 97.088  75.109  1.00 66.67  ? 231 THR   E C   1 
ATOM   6202 O O   . THR   D 4 243 ? 134.724 98.306  74.967  1.00 66.67  ? 231 THR   E O   1 
ATOM   6203 C CB  . THR   D 4 243 ? 132.293 97.252  76.075  1.00 66.67  ? 231 THR   E CB  1 
ATOM   6204 O OG1 . THR   D 4 243 ? 131.449 96.785  77.133  1.00 66.67  ? 231 THR   E OG1 1 
ATOM   6205 C CG2 . THR   D 4 243 ? 131.615 97.003  74.740  1.00 66.67  ? 231 THR   E CG2 1 
ATOM   6206 N N   . LYS   D 4 244 ? 135.293 96.197  74.403  1.00 71.23  ? 232 LYS   E N   1 
ATOM   6207 C CA  . LYS   D 4 244 ? 136.176 96.623  73.330  1.00 71.23  ? 232 LYS   E CA  1 
ATOM   6208 C C   . LYS   D 4 244 ? 135.378 97.310  72.232  1.00 71.23  ? 232 LYS   E C   1 
ATOM   6209 O O   . LYS   D 4 244 ? 134.252 96.915  71.921  1.00 71.23  ? 232 LYS   E O   1 
ATOM   6210 C CB  . LYS   D 4 244 ? 136.919 95.421  72.753  1.00 71.23  ? 232 LYS   E CB  1 
ATOM   6211 C CG  . LYS   D 4 244 ? 138.209 95.068  73.448  1.00 71.23  ? 232 LYS   E CG  1 
ATOM   6212 C CD  . LYS   D 4 244 ? 139.326 96.003  73.029  1.00 71.23  ? 232 LYS   E CD  1 
ATOM   6213 C CE  . LYS   D 4 244 ? 139.563 95.939  71.532  1.00 71.23  ? 232 LYS   E CE  1 
ATOM   6214 N NZ  . LYS   D 4 244 ? 140.036 94.594  71.102  1.00 71.23  ? 232 LYS   E NZ  1 
ATOM   6215 N N   . LEU   D 4 245 ? 135.962 98.347  71.647  1.00 74.32  ? 233 LEU   E N   1 
ATOM   6216 C CA  . LEU   D 4 245 ? 135.470 98.922  70.400  1.00 74.32  ? 233 LEU   E CA  1 
ATOM   6217 C C   . LEU   D 4 245 ? 136.605 98.849  69.390  1.00 74.32  ? 233 LEU   E C   1 
ATOM   6218 O O   . LEU   D 4 245 ? 137.518 99.678  69.408  1.00 74.32  ? 233 LEU   E O   1 
ATOM   6219 C CB  . LEU   D 4 245 ? 134.973 100.349 70.581  1.00 74.32  ? 233 LEU   E CB  1 
ATOM   6220 C CG  . LEU   D 4 245 ? 133.736 100.502 71.460  1.00 74.32  ? 233 LEU   E CG  1 
ATOM   6221 C CD1 . LEU   D 4 245 ? 133.419 101.967 71.678  1.00 74.32  ? 233 LEU   E CD1 1 
ATOM   6222 C CD2 . LEU   D 4 245 ? 132.548 99.783  70.855  1.00 74.32  ? 233 LEU   E CD2 1 
ATOM   6223 N N   . GLU   D 4 246 ? 136.552 97.848  68.522  1.00 83.37  ? 234 GLU   E N   1 
ATOM   6224 C CA  . GLU   D 4 246 ? 137.510 97.701  67.441  1.00 83.37  ? 234 GLU   E CA  1 
ATOM   6225 C C   . GLU   D 4 246 ? 136.964 98.392  66.193  1.00 83.37  ? 234 GLU   E C   1 
ATOM   6226 O O   . GLU   D 4 246 ? 136.033 99.199  66.260  1.00 83.37  ? 234 GLU   E O   1 
ATOM   6227 C CB  . GLU   D 4 246 ? 137.811 96.224  67.198  1.00 83.37  ? 234 GLU   E CB  1 
ATOM   6228 N N   . LEU   D 4 247 ? 137.541 98.084  65.038  1.00 88.28  ? 235 LEU   E N   1 
ATOM   6229 C CA  . LEU   D 4 247 ? 137.079 98.656  63.779  1.00 88.28  ? 235 LEU   E CA  1 
ATOM   6230 C C   . LEU   D 4 247 ? 136.180 97.671  63.035  1.00 88.28  ? 235 LEU   E C   1 
ATOM   6231 O O   . LEU   D 4 247 ? 135.598 97.998  62.001  1.00 88.28  ? 235 LEU   E O   1 
ATOM   6232 C CB  . LEU   D 4 247 ? 138.268 99.059  62.904  1.00 88.28  ? 235 LEU   E CB  1 
ATOM   6233 C CG  . LEU   D 4 247 ? 138.876 100.444 63.141  1.00 88.28  ? 235 LEU   E CG  1 
ATOM   6234 C CD1 . LEU   D 4 247 ? 137.846 101.532 62.871  1.00 88.28  ? 235 LEU   E CD1 1 
ATOM   6235 C CD2 . LEU   D 4 247 ? 139.444 100.578 64.545  1.00 88.28  ? 235 LEU   E CD2 1 
ATOM   6236 N N   . GLN   E 5 176 ? 105.941 117.920 165.549 1.00 60.41  ? 26  GLN   R N   1 
ATOM   6237 C CA  . GLN   E 5 176 ? 107.314 118.136 165.987 1.00 60.41  ? 26  GLN   R CA  1 
ATOM   6238 C C   . GLN   E 5 176 ? 108.260 118.094 164.801 1.00 60.41  ? 26  GLN   R C   1 
ATOM   6239 O O   . GLN   E 5 176 ? 109.264 118.800 164.768 1.00 60.41  ? 26  GLN   R O   1 
ATOM   6240 C CB  . GLN   E 5 176 ? 107.722 117.089 167.021 1.00 60.41  ? 26  GLN   R CB  1 
ATOM   6241 N N   . THR   E 5 177 ? 107.930 117.254 163.830 1.00 63.54  ? 27  THR   R N   1 
ATOM   6242 C CA  . THR   E 5 177 ? 108.737 117.095 162.633 1.00 63.54  ? 27  THR   R CA  1 
ATOM   6243 C C   . THR   E 5 177 ? 107.973 117.330 161.345 1.00 63.54  ? 27  THR   R C   1 
ATOM   6244 O O   . THR   E 5 177 ? 108.572 117.783 160.363 1.00 63.54  ? 27  THR   R O   1 
ATOM   6245 C CB  . THR   E 5 177 ? 109.351 115.688 162.585 1.00 63.54  ? 27  THR   R CB  1 
ATOM   6246 N N   . LEU   E 5 178 ? 106.672 117.040 161.321 1.00 62.18  ? 28  LEU   R N   1 
ATOM   6247 C CA  . LEU   E 5 178 ? 105.912 117.181 160.087 1.00 62.18  ? 28  LEU   R CA  1 
ATOM   6248 C C   . LEU   E 5 178 ? 105.960 118.610 159.567 1.00 62.18  ? 28  LEU   R C   1 
ATOM   6249 O O   . LEU   E 5 178 ? 105.966 118.834 158.351 1.00 62.18  ? 28  LEU   R O   1 
ATOM   6250 C CB  . LEU   E 5 178 ? 104.468 116.741 160.309 1.00 62.18  ? 28  LEU   R CB  1 
ATOM   6251 N N   . SER   E 5 179 ? 106.009 119.592 160.466 1.00 61.32  ? 29  SER   R N   1 
ATOM   6252 C CA  . SER   E 5 179 ? 105.988 120.982 160.026 1.00 61.32  ? 29  SER   R CA  1 
ATOM   6253 C C   . SER   E 5 179 ? 107.253 121.329 159.256 1.00 61.32  ? 29  SER   R C   1 
ATOM   6254 O O   . SER   E 5 179 ? 107.194 121.884 158.148 1.00 61.32  ? 29  SER   R O   1 
ATOM   6255 C CB  . SER   E 5 179 ? 105.815 121.909 161.230 1.00 61.32  ? 29  SER   R CB  1 
ATOM   6256 N N   . PHE   E 5 180 ? 108.410 121.006 159.831 1.00 62.60  ? 30  PHE   R N   1 
ATOM   6257 C CA  . PHE   E 5 180 ? 109.663 121.234 159.129 1.00 62.60  ? 30  PHE   R CA  1 
ATOM   6258 C C   . PHE   E 5 180 ? 109.707 120.435 157.838 1.00 62.60  ? 30  PHE   R C   1 
ATOM   6259 O O   . PHE   E 5 180 ? 110.202 120.922 156.814 1.00 62.60  ? 30  PHE   R O   1 
ATOM   6260 C CB  . PHE   E 5 180 ? 110.842 120.871 160.030 1.00 62.60  ? 30  PHE   R CB  1 
ATOM   6261 N N   . THR   E 5 181 ? 109.192 119.205 157.867 1.00 59.27  ? 31  THR   R N   1 
ATOM   6262 C CA  . THR   E 5 181 ? 109.173 118.390 156.660 1.00 59.27  ? 31  THR   R CA  1 
ATOM   6263 C C   . THR   E 5 181 ? 108.408 119.091 155.549 1.00 59.27  ? 31  THR   R C   1 
ATOM   6264 O O   . THR   E 5 181 ? 108.881 119.182 154.409 1.00 59.27  ? 31  THR   R O   1 
ATOM   6265 C CB  . THR   E 5 181 ? 108.555 117.027 156.963 1.00 59.27  ? 31  THR   R CB  1 
ATOM   6266 N N   . VAL   E 5 182 ? 107.232 119.622 155.876 1.00 59.19  ? 32  VAL   R N   1 
ATOM   6267 C CA  . VAL   E 5 182 ? 106.396 120.257 154.868 1.00 59.19  ? 32  VAL   R CA  1 
ATOM   6268 C C   . VAL   E 5 182 ? 107.053 121.525 154.352 1.00 59.19  ? 32  VAL   R C   1 
ATOM   6269 O O   . VAL   E 5 182 ? 107.035 121.802 153.145 1.00 59.19  ? 32  VAL   R O   1 
ATOM   6270 C CB  . VAL   E 5 182 ? 104.995 120.539 155.438 1.00 59.19  ? 32  VAL   R CB  1 
ATOM   6271 N N   . LEU   E 5 183 ? 107.615 122.331 155.254 1.00 62.86  ? 33  LEU   R N   1 
ATOM   6272 C CA  . LEU   E 5 183 ? 108.262 123.566 154.820 1.00 62.86  ? 33  LEU   R CA  1 
ATOM   6273 C C   . LEU   E 5 183 ? 109.416 123.268 153.876 1.00 62.86  ? 33  LEU   R C   1 
ATOM   6274 O O   . LEU   E 5 183 ? 109.561 123.913 152.825 1.00 62.86  ? 33  LEU   R O   1 
ATOM   6275 C CB  . LEU   E 5 183 ? 108.751 124.359 156.031 1.00 62.86  ? 33  LEU   R CB  1 
ATOM   6276 N N   . THR   E 5 184 ? 110.235 122.279 154.227 1.00 60.71  ? 34  THR   R N   1 
ATOM   6277 C CA  . THR   E 5 184 ? 111.315 121.877 153.343 1.00 60.71  ? 34  THR   R CA  1 
ATOM   6278 C C   . THR   E 5 184 ? 110.767 121.416 152.007 1.00 60.71  ? 34  THR   R C   1 
ATOM   6279 O O   . THR   E 5 184 ? 111.295 121.785 150.957 1.00 60.71  ? 34  THR   R O   1 
ATOM   6280 C CB  . THR   E 5 184 ? 112.144 120.770 153.992 1.00 60.71  ? 34  THR   R CB  1 
ATOM   6281 N N   . CYS   E 5 185 ? 109.690 120.630 152.026 1.00 61.44  ? 35  CYS   R N   1 
ATOM   6282 C CA  . CYS   E 5 185 ? 109.135 120.111 150.782 1.00 61.44  ? 35  CYS   R CA  1 
ATOM   6283 C C   . CYS   E 5 185 ? 108.667 121.235 149.870 1.00 61.44  ? 35  CYS   R C   1 
ATOM   6284 O O   . CYS   E 5 185 ? 108.926 121.214 148.663 1.00 61.44  ? 35  CYS   R O   1 
ATOM   6285 C CB  . CYS   E 5 185 ? 107.984 119.154 151.085 1.00 61.44  ? 35  CYS   R CB  1 
ATOM   6286 N N   . ILE   E 5 186 ? 107.981 122.229 150.430 1.00 63.74  ? 36  ILE   R N   1 
ATOM   6287 C CA  . ILE   E 5 186 ? 107.441 123.311 149.609 1.00 63.74  ? 36  ILE   R CA  1 
ATOM   6288 C C   . ILE   E 5 186 ? 108.569 124.162 149.038 1.00 63.74  ? 36  ILE   R C   1 
ATOM   6289 O O   . ILE   E 5 186 ? 108.589 124.484 147.837 1.00 63.74  ? 36  ILE   R O   1 
ATOM   6290 C CB  . ILE   E 5 186 ? 106.452 124.160 150.426 1.00 63.74  ? 36  ILE   R CB  1 
ATOM   6291 N N   . ILE   E 5 187 ? 109.528 124.539 149.891 1.00 64.42  ? 37  ILE   R N   1 
ATOM   6292 C CA  . ILE   E 5 187 ? 110.654 125.335 149.417 1.00 64.42  ? 37  ILE   R CA  1 
ATOM   6293 C C   . ILE   E 5 187 ? 111.433 124.565 148.362 1.00 64.42  ? 37  ILE   R C   1 
ATOM   6294 O O   . ILE   E 5 187 ? 111.913 125.136 147.379 1.00 64.42  ? 37  ILE   R O   1 
ATOM   6295 C CB  . ILE   E 5 187 ? 111.550 125.749 150.597 1.00 64.42  ? 37  ILE   R CB  1 
ATOM   6296 N N   . SER   E 5 188 ? 111.555 123.252 148.544 1.00 64.72  ? 38  SER   R N   1 
ATOM   6297 C CA  . SER   E 5 188 ? 112.255 122.423 147.580 1.00 64.72  ? 38  SER   R CA  1 
ATOM   6298 C C   . SER   E 5 188 ? 111.506 122.363 146.264 1.00 64.72  ? 38  SER   R C   1 
ATOM   6299 O O   . SER   E 5 188 ? 112.123 122.320 145.200 1.00 64.72  ? 38  SER   R O   1 
ATOM   6300 C CB  . SER   E 5 188 ? 112.453 121.019 148.148 1.00 64.72  ? 38  SER   R CB  1 
ATOM   6301 N N   . LEU   E 5 189 ? 110.181 122.324 146.309 1.00 68.12  ? 39  LEU   R N   1 
ATOM   6302 C CA  . LEU   E 5 189 ? 109.425 122.340 145.065 1.00 68.12  ? 39  LEU   R CA  1 
ATOM   6303 C C   . LEU   E 5 189 ? 109.700 123.624 144.298 1.00 68.12  ? 39  LEU   R C   1 
ATOM   6304 O O   . LEU   E 5 189 ? 109.982 123.602 143.089 1.00 68.12  ? 39  LEU   R O   1 
ATOM   6305 C CB  . LEU   E 5 189 ? 107.933 122.187 145.358 1.00 68.12  ? 39  LEU   R CB  1 
ATOM   6306 N N   . VAL   E 5 190 ? 109.665 124.757 145.003 1.00 69.93  ? 40  VAL   R N   1 
ATOM   6307 C CA  . VAL   E 5 190 ? 109.951 126.033 144.348 1.00 69.93  ? 40  VAL   R CA  1 
ATOM   6308 C C   . VAL   E 5 190 ? 111.365 126.034 143.775 1.00 69.93  ? 40  VAL   R C   1 
ATOM   6309 O O   . VAL   E 5 190 ? 111.597 126.468 142.636 1.00 69.93  ? 40  VAL   R O   1 
ATOM   6310 C CB  . VAL   E 5 190 ? 109.739 127.199 145.331 1.00 69.93  ? 40  VAL   R CB  1 
ATOM   6311 N N   . GLY   E 5 191 ? 112.330 125.548 144.557 1.00 71.60  ? 41  GLY   R N   1 
ATOM   6312 C CA  . GLY   E 5 191 ? 113.710 125.557 144.108 1.00 71.60  ? 41  GLY   R CA  1 
ATOM   6313 C C   . GLY   E 5 191 ? 113.944 124.635 142.931 1.00 71.60  ? 41  GLY   R C   1 
ATOM   6314 O O   . GLY   E 5 191 ? 114.730 124.947 142.034 1.00 71.60  ? 41  GLY   R O   1 
ATOM   6315 N N   . LEU   E 5 192 ? 113.275 123.483 142.922 1.00 70.38  ? 42  LEU   R N   1 
ATOM   6316 C CA  . LEU   E 5 192 ? 113.351 122.594 141.776 1.00 70.38  ? 42  LEU   R CA  1 
ATOM   6317 C C   . LEU   E 5 192 ? 112.808 123.279 140.536 1.00 70.38  ? 42  LEU   R C   1 
ATOM   6318 O O   . LEU   E 5 192 ? 113.390 123.165 139.453 1.00 70.38  ? 42  LEU   R O   1 
ATOM   6319 C CB  . LEU   E 5 192 ? 112.583 121.306 142.060 1.00 70.38  ? 42  LEU   R CB  1 
ATOM   6320 N N   . THR   E 5 193 ? 111.698 124.010 140.681 1.00 72.51  ? 43  THR   R N   1 
ATOM   6321 C CA  . THR   E 5 193 ? 111.138 124.733 139.542 1.00 72.51  ? 43  THR   R CA  1 
ATOM   6322 C C   . THR   E 5 193 ? 112.129 125.758 139.004 1.00 72.51  ? 43  THR   R C   1 
ATOM   6323 O O   . THR   E 5 193 ? 112.381 125.826 137.792 1.00 72.51  ? 43  THR   R O   1 
ATOM   6324 C CB  . THR   E 5 193 ? 109.827 125.410 139.942 1.00 72.51  ? 43  THR   R CB  1 
ATOM   6325 N N   . GLY   E 5 194 ? 112.715 126.555 139.897 1.00 71.84  ? 44  GLY   R N   1 
ATOM   6326 C CA  . GLY   E 5 194 ? 113.692 127.542 139.459 1.00 71.84  ? 44  GLY   R CA  1 
ATOM   6327 C C   . GLY   E 5 194 ? 114.906 126.914 138.797 1.00 71.84  ? 44  GLY   R C   1 
ATOM   6328 O O   . GLY   E 5 194 ? 115.369 127.378 137.750 1.00 71.84  ? 44  GLY   R O   1 
ATOM   6329 N N   . ASN   E 5 195 ? 115.435 125.846 139.394 1.00 72.00  ? 45  ASN   R N   1 
ATOM   6330 C CA  . ASN   E 5 195 ? 116.604 125.188 138.826 1.00 72.00  ? 45  ASN   R CA  1 
ATOM   6331 C C   . ASN   E 5 195 ? 116.285 124.582 137.468 1.00 72.00  ? 45  ASN   R C   1 
ATOM   6332 O O   . ASN   E 5 195 ? 117.124 124.595 136.562 1.00 72.00  ? 45  ASN   R O   1 
ATOM   6333 C CB  . ASN   E 5 195 ? 117.124 124.118 139.785 1.00 72.00  ? 45  ASN   R CB  1 
ATOM   6334 N N   . ALA   E 5 196 ? 115.080 124.036 137.309 1.00 72.99  ? 46  ALA   R N   1 
ATOM   6335 C CA  . ALA   E 5 196 ? 114.687 123.501 136.013 1.00 72.99  ? 46  ALA   R CA  1 
ATOM   6336 C C   . ALA   E 5 196 ? 114.598 124.606 134.975 1.00 72.99  ? 46  ALA   R C   1 
ATOM   6337 O O   . ALA   E 5 196 ? 114.979 124.409 133.813 1.00 72.99  ? 46  ALA   R O   1 
ATOM   6338 C CB  . ALA   E 5 196 ? 113.355 122.761 136.130 1.00 72.99  ? 46  ALA   R CB  1 
ATOM   6339 N N   . VAL   E 5 197 ? 114.089 125.772 135.370 1.00 70.96  ? 47  VAL   R N   1 
ATOM   6340 C CA  . VAL   E 5 197 ? 114.046 126.895 134.440 1.00 70.96  ? 47  VAL   R CA  1 
ATOM   6341 C C   . VAL   E 5 197 ? 115.456 127.256 133.998 1.00 70.96  ? 47  VAL   R C   1 
ATOM   6342 O O   . VAL   E 5 197 ? 115.723 127.470 132.809 1.00 70.96  ? 47  VAL   R O   1 
ATOM   6343 C CB  . VAL   E 5 197 ? 113.328 128.098 135.077 1.00 70.96  ? 47  VAL   R CB  1 
ATOM   6344 N N   . VAL   E 5 198 ? 116.381 127.319 134.958 1.00 71.97  ? 48  VAL   R N   1 
ATOM   6345 C CA  . VAL   E 5 198 ? 117.770 127.634 134.637 1.00 71.97  ? 48  VAL   R CA  1 
ATOM   6346 C C   . VAL   E 5 198 ? 118.353 126.581 133.707 1.00 71.97  ? 48  VAL   R C   1 
ATOM   6347 O O   . VAL   E 5 198 ? 119.121 126.896 132.790 1.00 71.97  ? 48  VAL   R O   1 
ATOM   6348 C CB  . VAL   E 5 198 ? 118.602 127.771 135.925 1.00 71.97  ? 48  VAL   R CB  1 
ATOM   6349 N N   . LEU   E 5 199 ? 118.005 125.314 133.934 1.00 72.11  ? 49  LEU   R N   1 
ATOM   6350 C CA  . LEU   E 5 199 ? 118.505 124.247 133.075 1.00 72.11  ? 49  LEU   R CA  1 
ATOM   6351 C C   . LEU   E 5 199 ? 118.016 124.422 131.648 1.00 72.11  ? 49  LEU   R C   1 
ATOM   6352 O O   . LEU   E 5 199 ? 118.792 124.294 130.696 1.00 72.11  ? 49  LEU   R O   1 
ATOM   6353 C CB  . LEU   E 5 199 ? 118.077 122.889 133.624 1.00 72.11  ? 49  LEU   R CB  1 
ATOM   6354 N N   . TRP   E 5 200 ? 116.735 124.739 131.480 1.00 74.74  ? 50  TRP   R N   1 
ATOM   6355 C CA  . TRP   E 5 200 ? 116.204 124.948 130.138 1.00 74.74  ? 50  TRP   R CA  1 
ATOM   6356 C C   . TRP   E 5 200 ? 116.872 126.137 129.460 1.00 74.74  ? 50  TRP   R C   1 
ATOM   6357 O O   . TRP   E 5 200 ? 117.233 126.069 128.278 1.00 74.74  ? 50  TRP   R O   1 
ATOM   6358 C CB  . TRP   E 5 200 ? 114.690 125.143 130.198 1.00 74.74  ? 50  TRP   R CB  1 
ATOM   6359 N N   . LEU   E 5 201 ? 117.037 127.239 130.191 1.00 76.12  ? 51  LEU   R N   1 
ATOM   6360 C CA  . LEU   E 5 201 ? 117.635 128.429 129.598 1.00 76.12  ? 51  LEU   R CA  1 
ATOM   6361 C C   . LEU   E 5 201 ? 119.069 128.160 129.166 1.00 76.12  ? 51  LEU   R C   1 
ATOM   6362 O O   . LEU   E 5 201 ? 119.446 128.447 128.026 1.00 76.12  ? 51  LEU   R O   1 
ATOM   6363 C CB  . LEU   E 5 201 ? 117.574 129.593 130.582 1.00 76.12  ? 51  LEU   R CB  1 
ATOM   6364 N N   . LEU   E 5 202 ? 119.876 127.572 130.050 1.00 77.05  ? 52  LEU   R N   1 
ATOM   6365 C CA  . LEU   E 5 202 ? 121.264 127.297 129.704 1.00 77.05  ? 52  LEU   R CA  1 
ATOM   6366 C C   . LEU   E 5 202 ? 121.404 126.134 128.732 1.00 77.05  ? 52  LEU   R C   1 
ATOM   6367 O O   . LEU   E 5 202 ? 122.494 125.926 128.192 1.00 77.05  ? 52  LEU   R O   1 
ATOM   6368 C CB  . LEU   E 5 202 ? 122.083 127.015 130.963 1.00 77.05  ? 52  LEU   R CB  1 
ATOM   6369 C CG  . LEU   E 5 202 ? 122.658 128.213 131.725 1.00 77.05  ? 52  LEU   R CG  1 
ATOM   6370 C CD1 . LEU   E 5 202 ? 123.590 129.016 130.830 1.00 77.05  ? 52  LEU   R CD1 1 
ATOM   6371 C CD2 . LEU   E 5 202 ? 121.564 129.098 132.305 1.00 77.05  ? 52  LEU   R CD2 1 
ATOM   6372 N N   . GLY   E 5 203 ? 120.342 125.367 128.505 1.00 80.59  ? 53  GLY   R N   1 
ATOM   6373 C CA  . GLY   E 5 203 ? 120.413 124.310 127.520 1.00 80.59  ? 53  GLY   R CA  1 
ATOM   6374 C C   . GLY   E 5 203 ? 120.042 124.757 126.123 1.00 80.59  ? 53  GLY   R C   1 
ATOM   6375 O O   . GLY   E 5 203 ? 120.651 124.315 125.145 1.00 80.59  ? 53  GLY   R O   1 
ATOM   6376 N N   . TYR   E 5 204 ? 119.046 125.627 126.010 1.00 83.18  ? 54  TYR   R N   1 
ATOM   6377 C CA  . TYR   E 5 204 ? 118.558 126.020 124.694 1.00 83.18  ? 54  TYR   R CA  1 
ATOM   6378 C C   . TYR   E 5 204 ? 118.650 127.511 124.417 1.00 83.18  ? 54  TYR   R C   1 
ATOM   6379 O O   . TYR   E 5 204 ? 119.053 127.901 123.319 1.00 83.18  ? 54  TYR   R O   1 
ATOM   6380 C CB  . TYR   E 5 204 ? 117.101 125.564 124.521 1.00 83.18  ? 54  TYR   R CB  1 
ATOM   6381 N N   . ARG   E 5 205 ? 118.288 128.360 125.380 1.00 84.48  ? 55  ARG   R N   1 
ATOM   6382 C CA  . ARG   E 5 205 ? 118.117 129.780 125.084 1.00 84.48  ? 55  ARG   R CA  1 
ATOM   6383 C C   . ARG   E 5 205 ? 119.454 130.491 124.912 1.00 84.48  ? 55  ARG   R C   1 
ATOM   6384 O O   . ARG   E 5 205 ? 119.593 131.355 124.038 1.00 84.48  ? 55  ARG   R O   1 
ATOM   6385 C CB  . ARG   E 5 205 ? 117.296 130.447 126.188 1.00 84.48  ? 55  ARG   R CB  1 
ATOM   6386 N N   . MET   E 5 206 ? 120.446 130.149 125.727 1.00 82.72  ? 56  MET   R N   1 
ATOM   6387 C CA  . MET   E 5 206 ? 121.690 130.898 125.789 1.00 82.72  ? 56  MET   R CA  1 
ATOM   6388 C C   . MET   E 5 206 ? 122.852 130.074 125.248 1.00 82.72  ? 56  MET   R C   1 
ATOM   6389 O O   . MET   E 5 206 ? 122.756 128.859 125.057 1.00 82.72  ? 56  MET   R O   1 
ATOM   6390 C CB  . MET   E 5 206 ? 121.980 131.343 127.228 1.00 82.72  ? 56  MET   R CB  1 
ATOM   6391 N N   . ARG   E 5 207 ? 123.961 130.764 125.002 1.00 79.99  ? 57  ARG   R N   1 
ATOM   6392 C CA  . ARG   E 5 207 ? 125.180 130.144 124.508 1.00 79.99  ? 57  ARG   R CA  1 
ATOM   6393 C C   . ARG   E 5 207 ? 126.067 129.742 125.686 1.00 79.99  ? 57  ARG   R C   1 
ATOM   6394 O O   . ARG   E 5 207 ? 125.639 129.740 126.842 1.00 79.99  ? 57  ARG   R O   1 
ATOM   6395 C CB  . ARG   E 5 207 ? 125.900 131.089 123.548 1.00 79.99  ? 57  ARG   R CB  1 
ATOM   6396 N N   . ARG   E 5 208 ? 127.320 129.401 125.403 1.00 75.78  ? 58  ARG   R N   1 
ATOM   6397 C CA  . ARG   E 5 208 ? 128.254 128.922 126.414 1.00 75.78  ? 58  ARG   R CA  1 
ATOM   6398 C C   . ARG   E 5 208 ? 129.310 129.987 126.687 1.00 75.78  ? 58  ARG   R C   1 
ATOM   6399 O O   . ARG   E 5 208 ? 130.001 130.434 125.765 1.00 75.78  ? 58  ARG   R O   1 
ATOM   6400 C CB  . ARG   E 5 208 ? 128.914 127.617 125.969 1.00 75.78  ? 58  ARG   R CB  1 
ATOM   6401 N N   . ASN   E 5 209 ? 129.429 130.385 127.950 1.00 67.48  ? 59  ASN   R N   1 
ATOM   6402 C CA  . ASN   E 5 209 ? 130.477 131.270 128.429 1.00 67.48  ? 59  ASN   R CA  1 
ATOM   6403 C C   . ASN   E 5 209 ? 131.547 130.434 129.121 1.00 67.48  ? 59  ASN   R C   1 
ATOM   6404 O O   . ASN   E 5 209 ? 131.583 129.211 129.000 1.00 67.48  ? 59  ASN   R O   1 
ATOM   6405 C CB  . ASN   E 5 209 ? 129.896 132.333 129.360 1.00 67.48  ? 59  ASN   R CB  1 
ATOM   6406 N N   . ALA   E 5 210 ? 132.461 131.094 129.823 1.00 63.82  ? 60  ALA   R N   1 
ATOM   6407 C CA  . ALA   E 5 210 ? 133.392 130.370 130.675 1.00 63.82  ? 60  ALA   R CA  1 
ATOM   6408 C C   . ALA   E 5 210 ? 132.824 130.102 132.060 1.00 63.82  ? 60  ALA   R C   1 
ATOM   6409 O O   . ALA   E 5 210 ? 133.438 129.365 132.836 1.00 63.82  ? 60  ALA   R O   1 
ATOM   6410 C CB  . ALA   E 5 210 ? 134.707 131.143 130.796 1.00 63.82  ? 60  ALA   R CB  1 
ATOM   6411 N N   . VAL   E 5 211 ? 131.676 130.685 132.379 1.00 62.10  ? 61  VAL   R N   1 
ATOM   6412 C CA  . VAL   E 5 211 ? 131.024 130.482 133.662 1.00 62.10  ? 61  VAL   R CA  1 
ATOM   6413 C C   . VAL   E 5 211 ? 129.689 129.759 133.514 1.00 62.10  ? 61  VAL   R C   1 
ATOM   6414 O O   . VAL   E 5 211 ? 129.235 129.124 134.478 1.00 62.10  ? 61  VAL   R O   1 
ATOM   6415 C CB  . VAL   E 5 211 ? 130.837 131.832 134.389 1.00 62.10  ? 61  VAL   R CB  1 
ATOM   6416 C CG1 . VAL   E 5 211 ? 130.084 131.683 135.692 1.00 62.10  ? 61  VAL   R CG1 1 
ATOM   6417 C CG2 . VAL   E 5 211 ? 132.189 132.481 134.632 1.00 62.10  ? 61  VAL   R CG2 1 
ATOM   6418 N N   . SER   E 5 212 ? 129.084 129.778 132.326 1.00 62.90  ? 62  SER   R N   1 
ATOM   6419 C CA  . SER   E 5 212 ? 127.767 129.180 132.144 1.00 62.90  ? 62  SER   R CA  1 
ATOM   6420 C C   . SER   E 5 212 ? 127.792 127.673 132.366 1.00 62.90  ? 62  SER   R C   1 
ATOM   6421 O O   . SER   E 5 212 ? 126.821 127.107 132.874 1.00 62.90  ? 62  SER   R O   1 
ATOM   6422 C CB  . SER   E 5 212 ? 127.235 129.504 130.749 1.00 62.90  ? 62  SER   R CB  1 
ATOM   6423 O OG  . SER   E 5 212 ? 127.034 130.898 130.593 1.00 62.90  ? 62  SER   R OG  1 
ATOM   6424 N N   . ILE   E 5 213 ? 128.874 126.998 131.970 1.00 60.47  ? 63  ILE   R N   1 
ATOM   6425 C CA  . ILE   E 5 213 ? 128.946 125.553 132.178 1.00 60.47  ? 63  ILE   R CA  1 
ATOM   6426 C C   . ILE   E 5 213 ? 128.906 125.217 133.658 1.00 60.47  ? 63  ILE   R C   1 
ATOM   6427 O O   . ILE   E 5 213 ? 128.186 124.305 134.084 1.00 60.47  ? 63  ILE   R O   1 
ATOM   6428 C CB  . ILE   E 5 213 ? 130.193 124.951 131.505 1.00 60.47  ? 63  ILE   R CB  1 
ATOM   6429 C CG1 . ILE   E 5 213 ? 130.146 125.126 129.987 1.00 60.47  ? 63  ILE   R CG1 1 
ATOM   6430 C CG2 . ILE   E 5 213 ? 130.348 123.487 131.875 1.00 60.47  ? 63  ILE   R CG2 1 
ATOM   6431 C CD1 . ILE   E 5 213 ? 130.739 126.392 129.484 1.00 60.47  ? 63  ILE   R CD1 1 
ATOM   6432 N N   . TYR   E 5 214 ? 129.680 125.937 134.464 1.00 56.66  ? 64  TYR   R N   1 
ATOM   6433 C CA  . TYR   E 5 214 ? 129.646 125.703 135.900 1.00 56.66  ? 64  TYR   R CA  1 
ATOM   6434 C C   . TYR   E 5 214 ? 128.262 125.949 136.475 1.00 56.66  ? 64  TYR   R C   1 
ATOM   6435 O O   . TYR   E 5 214 ? 127.806 125.202 137.345 1.00 56.66  ? 64  TYR   R O   1 
ATOM   6436 C CB  . TYR   E 5 214 ? 130.669 126.582 136.602 1.00 56.66  ? 64  TYR   R CB  1 
ATOM   6437 C CG  . TYR   E 5 214 ? 132.095 126.178 136.400 1.00 56.66  ? 64  TYR   R CG  1 
ATOM   6438 C CD1 . TYR   E 5 214 ? 132.445 124.855 136.267 1.00 56.66  ? 64  TYR   R CD1 1 
ATOM   6439 C CD2 . TYR   E 5 214 ? 133.099 127.117 136.399 1.00 56.66  ? 64  TYR   R CD2 1 
ATOM   6440 C CE1 . TYR   E 5 214 ? 133.751 124.486 136.111 1.00 56.66  ? 64  TYR   R CE1 1 
ATOM   6441 C CE2 . TYR   E 5 214 ? 134.402 126.756 136.240 1.00 56.66  ? 64  TYR   R CE2 1 
ATOM   6442 C CZ  . TYR   E 5 214 ? 134.725 125.441 136.099 1.00 56.66  ? 64  TYR   R CZ  1 
ATOM   6443 O OH  . TYR   E 5 214 ? 136.040 125.079 135.935 1.00 56.66  ? 64  TYR   R OH  1 
ATOM   6444 N N   . ILE   E 5 215 ? 127.588 127.004 136.027 1.00 58.26  ? 65  ILE   R N   1 
ATOM   6445 C CA  . ILE   E 5 215 ? 126.267 127.299 136.564 1.00 58.26  ? 65  ILE   R CA  1 
ATOM   6446 C C   . ILE   E 5 215 ? 125.274 126.227 136.149 1.00 58.26  ? 65  ILE   R C   1 
ATOM   6447 O O   . ILE   E 5 215 ? 124.393 125.843 136.926 1.00 58.26  ? 65  ILE   R O   1 
ATOM   6448 C CB  . ILE   E 5 215 ? 125.813 128.702 136.134 1.00 58.26  ? 65  ILE   R CB  1 
ATOM   6449 C CG1 . ILE   E 5 215 ? 126.663 129.760 136.831 1.00 58.26  ? 65  ILE   R CG1 1 
ATOM   6450 C CG2 . ILE   E 5 215 ? 124.357 128.918 136.464 1.00 58.26  ? 65  ILE   R CG2 1 
ATOM   6451 C CD1 . ILE   E 5 215 ? 126.466 131.156 136.285 1.00 58.26  ? 65  ILE   R CD1 1 
ATOM   6452 N N   . LEU   E 5 216 ? 125.402 125.718 134.924 1.00 62.01  ? 66  LEU   R N   1 
ATOM   6453 C CA  . LEU   E 5 216 ? 124.549 124.622 134.481 1.00 62.01  ? 66  LEU   R CA  1 
ATOM   6454 C C   . LEU   E 5 216 ? 124.777 123.379 135.325 1.00 62.01  ? 66  LEU   R C   1 
ATOM   6455 O O   . LEU   E 5 216 ? 123.824 122.689 135.698 1.00 62.01  ? 66  LEU   R O   1 
ATOM   6456 C CB  . LEU   E 5 216 ? 124.806 124.325 133.005 1.00 62.01  ? 66  LEU   R CB  1 
ATOM   6457 C CG  . LEU   E 5 216 ? 123.992 123.199 132.382 1.00 62.01  ? 66  LEU   R CG  1 
ATOM   6458 C CD1 . LEU   E 5 216 ? 122.510 123.546 132.380 1.00 62.01  ? 66  LEU   R CD1 1 
ATOM   6459 C CD2 . LEU   E 5 216 ? 124.478 122.913 130.973 1.00 62.01  ? 66  LEU   R CD2 1 
ATOM   6460 N N   . ASN   E 5 217 ? 126.035 123.089 135.651 1.00 59.23  ? 67  ASN   R N   1 
ATOM   6461 C CA  . ASN   E 5 217 ? 126.326 121.937 136.495 1.00 59.23  ? 67  ASN   R CA  1 
ATOM   6462 C C   . ASN   E 5 217 ? 125.787 122.127 137.905 1.00 59.23  ? 67  ASN   R C   1 
ATOM   6463 O O   . ASN   E 5 217 ? 125.253 121.188 138.500 1.00 59.23  ? 67  ASN   R O   1 
ATOM   6464 C CB  . ASN   E 5 217 ? 127.826 121.674 136.522 1.00 59.23  ? 67  ASN   R CB  1 
ATOM   6465 C CG  . ASN   E 5 217 ? 128.319 121.017 135.257 1.00 59.23  ? 67  ASN   R CG  1 
ATOM   6466 O OD1 . ASN   E 5 217 ? 127.635 121.024 134.235 1.00 59.23  ? 67  ASN   R OD1 1 
ATOM   6467 N ND2 . ASN   E 5 217 ? 129.500 120.428 135.319 1.00 59.23  ? 67  ASN   R ND2 1 
ATOM   6468 N N   . LEU   E 5 218 ? 125.925 123.326 138.461 1.00 57.55  ? 68  LEU   R N   1 
ATOM   6469 C CA  . LEU   E 5 218 ? 125.375 123.594 139.784 1.00 57.55  ? 68  LEU   R CA  1 
ATOM   6470 C C   . LEU   E 5 218 ? 123.858 123.470 139.789 1.00 57.55  ? 68  LEU   R C   1 
ATOM   6471 O O   . LEU   E 5 218 ? 123.277 122.897 140.717 1.00 57.55  ? 68  LEU   R O   1 
ATOM   6472 C CB  . LEU   E 5 218 ? 125.798 124.977 140.260 1.00 57.55  ? 68  LEU   R CB  1 
ATOM   6473 C CG  . LEU   E 5 218 ? 125.116 125.449 141.537 1.00 57.55  ? 68  LEU   R CG  1 
ATOM   6474 C CD1 . LEU   E 5 218 ? 125.592 124.647 142.734 1.00 57.55  ? 68  LEU   R CD1 1 
ATOM   6475 C CD2 . LEU   E 5 218 ? 125.372 126.916 141.733 1.00 57.55  ? 68  LEU   R CD2 1 
ATOM   6476 N N   . ALA   E 5 219 ? 123.198 123.986 138.753 1.00 60.04  ? 69  ALA   R N   1 
ATOM   6477 C CA  . ALA   E 5 219 ? 121.752 123.841 138.645 1.00 60.04  ? 69  ALA   R CA  1 
ATOM   6478 C C   . ALA   E 5 219 ? 121.342 122.378 138.503 1.00 60.04  ? 69  ALA   R C   1 
ATOM   6479 O O   . ALA   E 5 219 ? 120.334 121.954 139.076 1.00 60.04  ? 69  ALA   R O   1 
ATOM   6480 C CB  . ALA   E 5 219 ? 121.230 124.662 137.468 1.00 60.04  ? 69  ALA   R CB  1 
ATOM   6481 N N   . ALA   E 5 220 ? 122.098 121.592 137.732 1.00 58.60  ? 70  ALA   R N   1 
ATOM   6482 C CA  . ALA   E 5 220 ? 121.788 120.171 137.598 1.00 58.60  ? 70  ALA   R CA  1 
ATOM   6483 C C   . ALA   E 5 220 ? 121.969 119.429 138.918 1.00 58.60  ? 70  ALA   R C   1 
ATOM   6484 O O   . ALA   E 5 220 ? 121.150 118.575 139.280 1.00 58.60  ? 70  ALA   R O   1 
ATOM   6485 C CB  . ALA   E 5 220 ? 122.658 119.549 136.511 1.00 58.60  ? 70  ALA   R CB  1 
ATOM   6486 N N   . ALA   E 5 221 ? 123.045 119.731 139.640 1.00 59.17  ? 71  ALA   R N   1 
ATOM   6487 C CA  . ALA   E 5 221 ? 123.241 119.146 140.958 1.00 59.17  ? 71  ALA   R CA  1 
ATOM   6488 C C   . ALA   E 5 221 ? 122.110 119.529 141.892 1.00 59.17  ? 71  ALA   R C   1 
ATOM   6489 O O   . ALA   E 5 221 ? 121.654 118.711 142.698 1.00 59.17  ? 71  ALA   R O   1 
ATOM   6490 C CB  . ALA   E 5 221 ? 124.581 119.587 141.537 1.00 59.17  ? 71  ALA   R CB  1 
ATOM   6491 N N   . ASP   E 5 222 ? 121.645 120.773 141.801 1.00 61.79  ? 72  ASP   R N   1 
ATOM   6492 C CA  . ASP   E 5 222 ? 120.515 121.189 142.617 1.00 61.79  ? 72  ASP   R CA  1 
ATOM   6493 C C   . ASP   E 5 222 ? 119.257 120.431 142.228 1.00 61.79  ? 72  ASP   R C   1 
ATOM   6494 O O   . ASP   E 5 222 ? 118.456 120.064 143.094 1.00 61.79  ? 72  ASP   R O   1 
ATOM   6495 C CB  . ASP   E 5 222 ? 120.299 122.695 142.496 1.00 61.79  ? 72  ASP   R CB  1 
ATOM   6496 C CG  . ASP   E 5 222 ? 121.170 123.485 143.457 1.00 61.79  ? 72  ASP   R CG  1 
ATOM   6497 O OD1 . ASP   E 5 222 ? 121.565 122.926 144.502 1.00 61.79  ? 72  ASP   R OD1 1 
ATOM   6498 O OD2 . ASP   E 5 222 ? 121.458 124.665 143.167 1.00 61.79  ? 72  ASP   R OD2 1 
ATOM   6499 N N   . PHE   E 5 223 ? 119.073 120.177 140.932 1.00 61.77  ? 73  PHE   R N   1 
ATOM   6500 C CA  . PHE   E 5 223 ? 117.920 119.403 140.491 1.00 61.77  ? 73  PHE   R CA  1 
ATOM   6501 C C   . PHE   E 5 223 ? 117.941 118.005 141.082 1.00 61.77  ? 73  PHE   R C   1 
ATOM   6502 O O   . PHE   E 5 223 ? 116.922 117.519 141.577 1.00 61.77  ? 73  PHE   R O   1 
ATOM   6503 C CB  . PHE   E 5 223 ? 117.880 119.333 138.967 1.00 61.77  ? 73  PHE   R CB  1 
ATOM   6504 C CG  . PHE   E 5 223 ? 116.658 118.649 138.426 1.00 61.77  ? 73  PHE   R CG  1 
ATOM   6505 C CD1 . PHE   E 5 223 ? 115.448 119.320 138.344 1.00 61.77  ? 73  PHE   R CD1 1 
ATOM   6506 C CD2 . PHE   E 5 223 ? 116.718 117.332 138.004 1.00 61.77  ? 73  PHE   R CD2 1 
ATOM   6507 C CE1 . PHE   E 5 223 ? 114.326 118.695 137.848 1.00 61.77  ? 73  PHE   R CE1 1 
ATOM   6508 C CE2 . PHE   E 5 223 ? 115.597 116.699 137.505 1.00 61.77  ? 73  PHE   R CE2 1 
ATOM   6509 C CZ  . PHE   E 5 223 ? 114.398 117.381 137.428 1.00 61.77  ? 73  PHE   R CZ  1 
ATOM   6510 N N   . LEU   E 5 224 ? 119.101 117.350 141.057 1.00 60.38  ? 74  LEU   R N   1 
ATOM   6511 C CA  . LEU   E 5 224 ? 119.188 115.994 141.597 1.00 60.38  ? 74  LEU   R CA  1 
ATOM   6512 C C   . LEU   E 5 224 ? 119.012 115.983 143.112 1.00 60.38  ? 74  LEU   R C   1 
ATOM   6513 O O   . LEU   E 5 224 ? 118.281 115.141 143.654 1.00 60.38  ? 74  LEU   R O   1 
ATOM   6514 C CB  . LEU   E 5 224 ? 120.514 115.359 141.198 1.00 60.38  ? 74  LEU   R CB  1 
ATOM   6515 C CG  . LEU   E 5 224 ? 120.599 113.857 141.422 1.00 60.38  ? 74  LEU   R CG  1 
ATOM   6516 C CD1 . LEU   E 5 224 ? 119.452 113.163 140.712 1.00 60.38  ? 74  LEU   R CD1 1 
ATOM   6517 C CD2 . LEU   E 5 224 ? 121.927 113.327 140.918 1.00 60.38  ? 74  LEU   R CD2 1 
ATOM   6518 N N   . PHE   E 5 225 ? 119.649 116.926 143.810 1.00 58.21  ? 75  PHE   R N   1 
ATOM   6519 C CA  . PHE   E 5 225 ? 119.502 117.002 145.256 1.00 58.21  ? 75  PHE   R CA  1 
ATOM   6520 C C   . PHE   E 5 225 ? 118.052 117.233 145.647 1.00 58.21  ? 75  PHE   R C   1 
ATOM   6521 O O   . PHE   E 5 225 ? 117.525 116.561 146.543 1.00 58.21  ? 75  PHE   R O   1 
ATOM   6522 C CB  . PHE   E 5 225 ? 120.387 118.113 145.811 1.00 58.21  ? 75  PHE   R CB  1 
ATOM   6523 C CG  . PHE   E 5 225 ? 120.488 118.121 147.295 1.00 58.21  ? 75  PHE   R CG  1 
ATOM   6524 C CD1 . PHE   E 5 225 ? 121.532 117.492 147.925 1.00 58.21  ? 75  PHE   R CD1 1 
ATOM   6525 C CD2 . PHE   E 5 225 ? 119.546 118.770 148.061 1.00 58.21  ? 75  PHE   R CD2 1 
ATOM   6526 C CE1 . PHE   E 5 225 ? 121.627 117.491 149.295 1.00 58.21  ? 75  PHE   R CE1 1 
ATOM   6527 C CE2 . PHE   E 5 225 ? 119.631 118.776 149.424 1.00 58.21  ? 75  PHE   R CE2 1 
ATOM   6528 C CZ  . PHE   E 5 225 ? 120.674 118.139 150.049 1.00 58.21  ? 75  PHE   R CZ  1 
ATOM   6529 N N   . LEU   E 5 226 ? 117.372 118.160 144.973 1.00 61.23  ? 76  LEU   R N   1 
ATOM   6530 C CA  . LEU   E 5 226 ? 116.005 118.449 145.369 1.00 61.23  ? 76  LEU   R CA  1 
ATOM   6531 C C   . LEU   E 5 226 ? 115.012 117.407 144.884 1.00 61.23  ? 76  LEU   R C   1 
ATOM   6532 O O   . LEU   E 5 226 ? 113.966 117.240 145.513 1.00 61.23  ? 76  LEU   R O   1 
ATOM   6533 C CB  . LEU   E 5 226 ? 115.593 119.831 144.896 1.00 61.23  ? 76  LEU   R CB  1 
ATOM   6534 C CG  . LEU   E 5 226 ? 116.197 120.905 145.791 1.00 61.23  ? 76  LEU   R CG  1 
ATOM   6535 C CD1 . LEU   E 5 226 ? 115.674 122.288 145.414 1.00 61.23  ? 76  LEU   R CD1 1 
ATOM   6536 C CD2 . LEU   E 5 226 ? 115.934 120.592 147.240 1.00 61.23  ? 76  LEU   R CD2 1 
ATOM   6537 N N   . SER   E 5 227 ? 115.309 116.683 143.806 1.00 62.18  ? 77  SER   R N   1 
ATOM   6538 C CA  . SER   E 5 227 ? 114.480 115.539 143.454 1.00 62.18  ? 77  SER   R CA  1 
ATOM   6539 C C   . SER   E 5 227 ? 114.570 114.468 144.528 1.00 62.18  ? 77  SER   R C   1 
ATOM   6540 O O   . SER   E 5 227 ? 113.557 113.877 144.933 1.00 62.18  ? 77  SER   R O   1 
ATOM   6541 C CB  . SER   E 5 227 ? 114.904 114.981 142.096 1.00 62.18  ? 77  SER   R CB  1 
ATOM   6542 O OG  . SER   E 5 227 ? 116.207 114.428 142.161 1.00 62.18  ? 77  SER   R OG  1 
ATOM   6543 N N   . PHE   E 5 228 ? 115.782 114.213 145.019 1.00 63.54  ? 78  PHE   R N   1 
ATOM   6544 C CA  . PHE   E 5 228 ? 115.905 113.274 146.124 1.00 63.54  ? 78  PHE   R CA  1 
ATOM   6545 C C   . PHE   E 5 228 ? 115.213 113.791 147.372 1.00 63.54  ? 78  PHE   R C   1 
ATOM   6546 O O   . PHE   E 5 228 ? 114.667 113.006 148.145 1.00 63.54  ? 78  PHE   R O   1 
ATOM   6547 C CB  . PHE   E 5 228 ? 117.365 112.966 146.415 1.00 63.54  ? 78  PHE   R CB  1 
ATOM   6548 C CG  . PHE   E 5 228 ? 117.871 111.766 145.692 1.00 63.54  ? 78  PHE   R CG  1 
ATOM   6549 C CD1 . PHE   E 5 228 ? 117.454 111.497 144.407 1.00 63.54  ? 78  PHE   R CD1 1 
ATOM   6550 C CD2 . PHE   E 5 228 ? 118.734 110.891 146.306 1.00 63.54  ? 78  PHE   R CD2 1 
ATOM   6551 C CE1 . PHE   E 5 228 ? 117.909 110.390 143.739 1.00 63.54  ? 78  PHE   R CE1 1 
ATOM   6552 C CE2 . PHE   E 5 228 ? 119.186 109.785 145.647 1.00 63.54  ? 78  PHE   R CE2 1 
ATOM   6553 C CZ  . PHE   E 5 228 ? 118.777 109.532 144.358 1.00 63.54  ? 78  PHE   R CZ  1 
ATOM   6554 N N   . GLN   E 5 229 ? 115.213 115.099 147.588 1.00 62.75  ? 79  GLN   R N   1 
ATOM   6555 C CA  . GLN   E 5 229 ? 114.469 115.627 148.726 1.00 62.75  ? 79  GLN   R CA  1 
ATOM   6556 C C   . GLN   E 5 229 ? 112.967 115.446 148.543 1.00 62.75  ? 79  GLN   R C   1 
ATOM   6557 O O   . GLN   E 5 229 ? 112.240 115.196 149.514 1.00 62.75  ? 79  GLN   R O   1 
ATOM   6558 C CB  . GLN   E 5 229 ? 114.803 117.090 148.942 1.00 62.75  ? 79  GLN   R CB  1 
ATOM   6559 C CG  . GLN   E 5 229 ? 114.404 117.541 150.292 1.00 62.75  ? 79  GLN   R CG  1 
ATOM   6560 C CD  . GLN   E 5 229 ? 115.201 116.828 151.322 1.00 62.75  ? 79  GLN   R CD  1 
ATOM   6561 O OE1 . GLN   E 5 229 ? 116.372 116.536 151.110 1.00 62.75  ? 79  GLN   R OE1 1 
ATOM   6562 N NE2 . GLN   E 5 229 ? 114.583 116.538 152.457 1.00 62.75  ? 79  GLN   R NE2 1 
ATOM   6563 N N   . ILE   E 5 230 ? 112.483 115.583 147.309 1.00 66.36  ? 80  ILE   R N   1 
ATOM   6564 C CA  . ILE   E 5 230 ? 111.068 115.360 147.038 1.00 66.36  ? 80  ILE   R CA  1 
ATOM   6565 C C   . ILE   E 5 230 ? 110.689 113.927 147.376 1.00 66.36  ? 80  ILE   R C   1 
ATOM   6566 O O   . ILE   E 5 230 ? 109.666 113.675 148.023 1.00 66.36  ? 80  ILE   R O   1 
ATOM   6567 C CB  . ILE   E 5 230 ? 110.740 115.704 145.573 1.00 66.36  ? 80  ILE   R CB  1 
ATOM   6568 C CG1 . ILE   E 5 230 ? 110.745 117.221 145.366 1.00 66.36  ? 80  ILE   R CG1 1 
ATOM   6569 C CG2 . ILE   E 5 230 ? 109.400 115.108 145.165 1.00 66.36  ? 80  ILE   R CG2 1 
ATOM   6570 C CD1 . ILE   E 5 230 ? 109.587 117.932 146.032 1.00 66.36  ? 80  ILE   R CD1 1 
ATOM   6571 N N   . ILE   E 5 231 ? 111.512 112.964 146.960 1.00 64.51  ? 81  ILE   R N   1 
ATOM   6572 C CA  . ILE   E 5 231 ? 111.185 111.586 147.307 1.00 64.51  ? 81  ILE   R CA  1 
ATOM   6573 C C   . ILE   E 5 231 ? 111.441 111.310 148.784 1.00 64.51  ? 81  ILE   R C   1 
ATOM   6574 O O   . ILE   E 5 231 ? 110.887 110.360 149.338 1.00 64.51  ? 81  ILE   R O   1 
ATOM   6575 C CB  . ILE   E 5 231 ? 111.939 110.589 146.407 1.00 64.51  ? 81  ILE   R CB  1 
ATOM   6576 C CG1 . ILE   E 5 231 ? 113.447 110.686 146.613 1.00 64.51  ? 81  ILE   R CG1 1 
ATOM   6577 C CG2 . ILE   E 5 231 ? 111.586 110.821 144.945 1.00 64.51  ? 81  ILE   R CG2 1 
ATOM   6578 C CD1 . ILE   E 5 231 ? 114.225 109.597 145.908 1.00 64.51  ? 81  ILE   R CD1 1 
ATOM   6579 N N   . ARG   E 5 232 ? 112.266 112.125 149.437 1.00 68.34  ? 82  ARG   R N   1 
ATOM   6580 C CA  . ARG   E 5 232 ? 112.434 112.026 150.882 1.00 68.34  ? 82  ARG   R CA  1 
ATOM   6581 C C   . ARG   E 5 232 ? 111.166 112.420 151.612 1.00 68.34  ? 82  ARG   R C   1 
ATOM   6582 O O   . ARG   E 5 232 ? 110.784 111.783 152.601 1.00 68.34  ? 82  ARG   R O   1 
ATOM   6583 C CB  . ARG   E 5 232 ? 113.580 112.930 151.337 1.00 68.34  ? 82  ARG   R CB  1 
ATOM   6584 C CG  . ARG   E 5 232 ? 113.571 113.267 152.831 1.00 68.34  ? 82  ARG   R CG  1 
ATOM   6585 C CD  . ARG   E 5 232 ? 114.315 112.214 153.604 1.00 68.34  ? 82  ARG   R CD  1 
ATOM   6586 N NE  . ARG   E 5 232 ? 115.605 111.982 152.971 1.00 68.34  ? 82  ARG   R NE  1 
ATOM   6587 C CZ  . ARG   E 5 232 ? 116.329 110.883 153.117 1.00 68.34  ? 82  ARG   R CZ  1 
ATOM   6588 N NH1 . ARG   E 5 232 ? 117.487 110.773 152.486 1.00 68.34  ? 82  ARG   R NH1 1 
ATOM   6589 N NH2 . ARG   E 5 232 ? 115.894 109.896 153.884 1.00 68.34  ? 82  ARG   R NH2 1 
ATOM   6590 N N   . SER   E 5 233 ? 110.516 113.481 151.150 1.00 69.92  ? 83  SER   R N   1 
ATOM   6591 C CA  . SER   E 5 233 ? 109.415 114.081 151.899 1.00 69.92  ? 83  SER   R CA  1 
ATOM   6592 C C   . SER   E 5 233 ? 108.327 113.090 152.279 1.00 69.92  ? 83  SER   R C   1 
ATOM   6593 O O   . SER   E 5 233 ? 107.950 113.045 153.460 1.00 69.92  ? 83  SER   R O   1 
ATOM   6594 C CB  . SER   E 5 233 ? 108.827 115.237 151.081 1.00 69.92  ? 83  SER   R CB  1 
ATOM   6595 O OG  . SER   E 5 233 ? 108.220 114.761 149.894 1.00 69.92  ? 83  SER   R OG  1 
ATOM   6596 N N   . PRO   E 5 234 ? 107.809 112.275 151.380 1.00 74.57  ? 84  PRO   R N   1 
ATOM   6597 C CA  . PRO   E 5 234 ? 106.666 111.433 151.746 1.00 74.57  ? 84  PRO   R CA  1 
ATOM   6598 C C   . PRO   E 5 234 ? 107.073 110.215 152.550 1.00 74.57  ? 84  PRO   R C   1 
ATOM   6599 O O   . PRO   E 5 234 ? 106.341 109.784 153.444 1.00 74.57  ? 84  PRO   R O   1 
ATOM   6600 C CB  . PRO   E 5 234 ? 106.074 111.037 150.388 1.00 74.57  ? 84  PRO   R CB  1 
ATOM   6601 N N   . LEU   E 5 235 ? 108.242 109.655 152.245 1.00 75.29  ? 85  LEU   R N   1 
ATOM   6602 C CA  . LEU   E 5 235 ? 108.650 108.407 152.875 1.00 75.29  ? 85  LEU   R CA  1 
ATOM   6603 C C   . LEU   E 5 235 ? 108.924 108.567 154.367 1.00 75.29  ? 85  LEU   R C   1 
ATOM   6604 O O   . LEU   E 5 235 ? 108.982 107.565 155.081 1.00 75.29  ? 85  LEU   R O   1 
ATOM   6605 C CB  . LEU   E 5 235 ? 109.875 107.854 152.141 1.00 75.29  ? 85  LEU   R CB  1 
ATOM   6606 C CG  . LEU   E 5 235 ? 110.457 106.468 152.436 1.00 75.29  ? 85  LEU   R CG  1 
ATOM   6607 C CD1 . LEU   E 5 235 ? 111.162 105.950 151.197 1.00 75.29  ? 85  LEU   R CD1 1 
ATOM   6608 C CD2 . LEU   E 5 235 ? 111.438 106.492 153.591 1.00 75.29  ? 85  LEU   R CD2 1 
ATOM   6609 N N   . ARG   E 5 236 ? 109.077 109.799 154.859 1.00 81.34  ? 86  ARG   R N   1 
ATOM   6610 C CA  . ARG   E 5 236 ? 109.414 109.992 156.266 1.00 81.34  ? 86  ARG   R CA  1 
ATOM   6611 C C   . ARG   E 5 236 ? 108.247 109.646 157.179 1.00 81.34  ? 86  ARG   R C   1 
ATOM   6612 O O   . ARG   E 5 236 ? 108.421 108.927 158.169 1.00 81.34  ? 86  ARG   R O   1 
ATOM   6613 C CB  . ARG   E 5 236 ? 109.858 111.430 156.513 1.00 81.34  ? 86  ARG   R CB  1 
ATOM   6614 C CG  . ARG   E 5 236 ? 110.469 111.633 157.883 1.00 81.34  ? 86  ARG   R CG  1 
ATOM   6615 C CD  . ARG   E 5 236 ? 110.597 113.104 158.242 1.00 81.34  ? 86  ARG   R CD  1 
ATOM   6616 N NE  . ARG   E 5 236 ? 111.326 113.285 159.494 1.00 81.34  ? 86  ARG   R NE  1 
ATOM   6617 C CZ  . ARG   E 5 236 ? 110.799 113.108 160.701 1.00 81.34  ? 86  ARG   R CZ  1 
ATOM   6618 N NH1 . ARG   E 5 236 ? 109.529 112.746 160.829 1.00 81.34  ? 86  ARG   R NH1 1 
ATOM   6619 N NH2 . ARG   E 5 236 ? 111.542 113.294 161.784 1.00 81.34  ? 86  ARG   R NH2 1 
ATOM   6620 N N   . LEU   E 5 237 ? 107.053 110.159 156.876 1.00 82.26  ? 87  LEU   R N   1 
ATOM   6621 C CA  . LEU   E 5 237 ? 105.884 109.810 157.677 1.00 82.26  ? 87  LEU   R CA  1 
ATOM   6622 C C   . LEU   E 5 237 ? 105.572 108.325 157.582 1.00 82.26  ? 87  LEU   R C   1 
ATOM   6623 O O   . LEU   E 5 237 ? 105.226 107.695 158.588 1.00 82.26  ? 87  LEU   R O   1 
ATOM   6624 C CB  . LEU   E 5 237 ? 104.675 110.633 157.236 1.00 82.26  ? 87  LEU   R CB  1 
ATOM   6625 C CG  . LEU   E 5 237 ? 104.394 111.928 158.003 1.00 82.26  ? 87  LEU   R CG  1 
ATOM   6626 C CD1 . LEU   E 5 237 ? 104.021 111.619 159.445 1.00 82.26  ? 87  LEU   R CD1 1 
ATOM   6627 C CD2 . LEU   E 5 237 ? 105.580 112.880 157.940 1.00 82.26  ? 87  LEU   R CD2 1 
ATOM   6628 N N   . ILE   E 5 238 ? 105.701 107.752 156.392 1.00 82.68  ? 88  ILE   R N   1 
ATOM   6629 C CA  . ILE   E 5 238 ? 105.417 106.348 156.141 1.00 82.68  ? 88  ILE   R CA  1 
ATOM   6630 C C   . ILE   E 5 238 ? 106.509 105.503 156.773 1.00 82.68  ? 88  ILE   R C   1 
ATOM   6631 O O   . ILE   E 5 238 ? 107.700 105.802 156.637 1.00 82.68  ? 88  ILE   R O   1 
ATOM   6632 C CB  . ILE   E 5 238 ? 105.308 106.074 154.631 1.00 82.68  ? 88  ILE   R CB  1 
ATOM   6633 C CG1 . ILE   E 5 238 ? 104.136 106.857 154.038 1.00 82.68  ? 88  ILE   R CG1 1 
ATOM   6634 C CG2 . ILE   E 5 238 ? 105.148 104.588 154.363 1.00 82.68  ? 88  ILE   R CG2 1 
ATOM   6635 C CD1 . ILE   E 5 238 ? 104.104 106.858 152.524 1.00 82.68  ? 88  ILE   R CD1 1 
ATOM   6636 N N   . ASN   E 5 239 ? 106.106 104.446 157.473 1.00 88.04  ? 89  ASN   R N   1 
ATOM   6637 C CA  . ASN   E 5 239 ? 107.051 103.540 158.124 1.00 88.04  ? 89  ASN   R CA  1 
ATOM   6638 C C   . ASN   E 5 239 ? 107.671 102.646 157.058 1.00 88.04  ? 89  ASN   R C   1 
ATOM   6639 O O   . ASN   E 5 239 ? 107.062 101.686 156.584 1.00 88.04  ? 89  ASN   R O   1 
ATOM   6640 C CB  . ASN   E 5 239 ? 106.356 102.723 159.206 1.00 88.04  ? 89  ASN   R CB  1 
ATOM   6641 N N   . ILE   E 5 240 ? 108.900 102.969 156.673 1.00 86.11  ? 90  ILE   R N   1 
ATOM   6642 C CA  . ILE   E 5 240 ? 109.640 102.193 155.692 1.00 86.11  ? 90  ILE   R CA  1 
ATOM   6643 C C   . ILE   E 5 240 ? 110.905 101.647 156.349 1.00 86.11  ? 90  ILE   R C   1 
ATOM   6644 O O   . ILE   E 5 240 ? 111.295 102.058 157.442 1.00 86.11  ? 90  ILE   R O   1 
ATOM   6645 C CB  . ILE   E 5 240 ? 109.976 103.016 154.434 1.00 86.11  ? 90  ILE   R CB  1 
ATOM   6646 N N   . SER   E 5 241 ? 111.546 100.702 155.662 1.00 84.93  ? 91  SER   R N   1 
ATOM   6647 C CA  . SER   E 5 241 ? 112.748 100.069 156.188 1.00 84.93  ? 91  SER   R CA  1 
ATOM   6648 C C   . SER   E 5 241 ? 113.847 101.098 156.402 1.00 84.93  ? 91  SER   R C   1 
ATOM   6649 O O   . SER   E 5 241 ? 114.157 101.892 155.511 1.00 84.93  ? 91  SER   R O   1 
ATOM   6650 C CB  . SER   E 5 241 ? 113.227 98.977  155.234 1.00 84.93  ? 91  SER   R CB  1 
ATOM   6651 N N   . HIS   E 5 242 ? 114.446 101.068 157.591 1.00 85.13  ? 92  HIS   R N   1 
ATOM   6652 C CA  . HIS   E 5 242 ? 115.451 102.060 157.945 1.00 85.13  ? 92  HIS   R CA  1 
ATOM   6653 C C   . HIS   E 5 242 ? 116.730 101.878 157.142 1.00 85.13  ? 92  HIS   R C   1 
ATOM   6654 O O   . HIS   E 5 242 ? 117.460 102.849 156.912 1.00 85.13  ? 92  HIS   R O   1 
ATOM   6655 C CB  . HIS   E 5 242 ? 115.714 101.988 159.444 1.00 85.13  ? 92  HIS   R CB  1 
ATOM   6656 C CG  . HIS   E 5 242 ? 114.462 101.962 160.260 1.00 85.13  ? 92  HIS   R CG  1 
ATOM   6657 N ND1 . HIS   E 5 242 ? 113.873 103.104 160.758 1.00 85.13  ? 92  HIS   R ND1 1 
ATOM   6658 C CD2 . HIS   E 5 242 ? 113.666 100.934 160.637 1.00 85.13  ? 92  HIS   R CD2 1 
ATOM   6659 C CE1 . HIS   E 5 242 ? 112.779 102.779 161.423 1.00 85.13  ? 92  HIS   R CE1 1 
ATOM   6660 N NE2 . HIS   E 5 242 ? 112.631 101.468 161.365 1.00 85.13  ? 92  HIS   R NE2 1 
ATOM   6661 N N   . LEU   E 5 243 ? 117.014 100.654 156.698 1.00 80.15  ? 93  LEU   R N   1 
ATOM   6662 C CA  . LEU   E 5 243 ? 118.102 100.459 155.751 1.00 80.15  ? 93  LEU   R CA  1 
ATOM   6663 C C   . LEU   E 5 243 ? 117.829 101.211 154.458 1.00 80.15  ? 93  LEU   R C   1 
ATOM   6664 O O   . LEU   E 5 243 ? 118.739 101.815 153.876 1.00 80.15  ? 93  LEU   R O   1 
ATOM   6665 C CB  . LEU   E 5 243 ? 118.300 98.970  155.475 1.00 80.15  ? 93  LEU   R CB  1 
ATOM   6666 N N   . ILE   E 5 244 ? 116.577 101.197 153.999 1.00 79.62  ? 94  ILE   R N   1 
ATOM   6667 C CA  . ILE   E 5 244 ? 116.221 101.963 152.810 1.00 79.62  ? 94  ILE   R CA  1 
ATOM   6668 C C   . ILE   E 5 244 ? 116.432 103.449 153.054 1.00 79.62  ? 94  ILE   R C   1 
ATOM   6669 O O   . ILE   E 5 244 ? 116.902 104.179 152.172 1.00 79.62  ? 94  ILE   R O   1 
ATOM   6670 C CB  . ILE   E 5 244 ? 114.773 101.658 152.388 1.00 79.62  ? 94  ILE   R CB  1 
ATOM   6671 N N   . ARG   E 5 245 ? 116.090 103.922 154.252 1.00 81.07  ? 95  ARG   R N   1 
ATOM   6672 C CA  . ARG   E 5 245 ? 116.282 105.331 154.571 1.00 81.07  ? 95  ARG   R CA  1 
ATOM   6673 C C   . ARG   E 5 245 ? 117.757 105.705 154.543 1.00 81.07  ? 95  ARG   R C   1 
ATOM   6674 O O   . ARG   E 5 245 ? 118.135 106.745 153.996 1.00 81.07  ? 95  ARG   R O   1 
ATOM   6675 C CB  . ARG   E 5 245 ? 115.665 105.645 155.933 1.00 81.07  ? 95  ARG   R CB  1 
ATOM   6676 C CG  . ARG   E 5 245 ? 114.148 105.600 155.933 1.00 81.07  ? 95  ARG   R CG  1 
ATOM   6677 C CD  . ARG   E 5 245 ? 113.575 106.090 157.248 1.00 81.07  ? 95  ARG   R CD  1 
ATOM   6678 N NE  . ARG   E 5 245 ? 112.115 106.061 157.255 1.00 81.07  ? 95  ARG   R NE  1 
ATOM   6679 C CZ  . ARG   E 5 245 ? 111.368 106.348 158.315 1.00 81.07  ? 95  ARG   R CZ  1 
ATOM   6680 N NH1 . ARG   E 5 245 ? 110.045 106.296 158.231 1.00 81.07  ? 95  ARG   R NH1 1 
ATOM   6681 N NH2 . ARG   E 5 245 ? 111.942 106.688 159.461 1.00 81.07  ? 95  ARG   R NH2 1 
ATOM   6682 N N   . LYS   E 5 246 ? 118.608 104.868 155.124 1.00 76.50  ? 96  LYS   R N   1 
ATOM   6683 C CA  . LYS   E 5 246 ? 120.031 105.166 155.090 1.00 76.50  ? 96  LYS   R CA  1 
ATOM   6684 C C   . LYS   E 5 246 ? 120.565 105.141 153.665 1.00 76.50  ? 96  LYS   R C   1 
ATOM   6685 O O   . LYS   E 5 246 ? 121.414 105.965 153.298 1.00 76.50  ? 96  LYS   R O   1 
ATOM   6686 C CB  . LYS   E 5 246 ? 120.794 104.185 155.974 1.00 76.50  ? 96  LYS   R CB  1 
ATOM   6687 C CG  . LYS   E 5 246 ? 120.335 104.189 157.420 1.00 76.50  ? 96  LYS   R CG  1 
ATOM   6688 C CD  . LYS   E 5 246 ? 120.810 105.439 158.138 1.00 76.50  ? 96  LYS   R CD  1 
ATOM   6689 C CE  . LYS   E 5 246 ? 120.060 105.644 159.443 1.00 76.50  ? 96  LYS   R CE  1 
ATOM   6690 N NZ  . LYS   E 5 246 ? 120.914 106.299 160.467 1.00 76.50  ? 96  LYS   R NZ  1 
ATOM   6691 N N   . ILE   E 5 247 ? 120.090 104.200 152.849 1.00 75.12  ? 97  ILE   R N   1 
ATOM   6692 C CA  . ILE   E 5 247 ? 120.523 104.154 151.457 1.00 75.12  ? 97  ILE   R CA  1 
ATOM   6693 C C   . ILE   E 5 247 ? 120.142 105.445 150.750 1.00 75.12  ? 97  ILE   R C   1 
ATOM   6694 O O   . ILE   E 5 247 ? 120.935 106.016 149.984 1.00 75.12  ? 97  ILE   R O   1 
ATOM   6695 C CB  . ILE   E 5 247 ? 119.928 102.920 150.754 1.00 75.12  ? 97  ILE   R CB  1 
ATOM   6696 C CG1 . ILE   E 5 247 ? 120.636 101.648 151.224 1.00 75.12  ? 97  ILE   R CG1 1 
ATOM   6697 C CG2 . ILE   E 5 247 ? 120.030 103.058 149.243 1.00 75.12  ? 97  ILE   R CG2 1 
ATOM   6698 C CD1 . ILE   E 5 247 ? 119.960 100.371 150.776 1.00 75.12  ? 97  ILE   R CD1 1 
ATOM   6699 N N   . LEU   E 5 248 ? 118.926 105.928 151.001 1.00 72.48  ? 98  LEU   R N   1 
ATOM   6700 C CA  . LEU   E 5 248 ? 118.511 107.199 150.424 1.00 72.48  ? 98  LEU   R CA  1 
ATOM   6701 C C   . LEU   E 5 248 ? 119.402 108.337 150.902 1.00 72.48  ? 98  LEU   R C   1 
ATOM   6702 O O   . LEU   E 5 248 ? 119.778 109.209 150.114 1.00 72.48  ? 98  LEU   R O   1 
ATOM   6703 C CB  . LEU   E 5 248 ? 117.054 107.492 150.770 1.00 72.48  ? 98  LEU   R CB  1 
ATOM   6704 C CG  . LEU   E 5 248 ? 116.503 108.662 149.966 1.00 72.48  ? 98  LEU   R CG  1 
ATOM   6705 C CD1 . LEU   E 5 248 ? 116.437 108.273 148.505 1.00 72.48  ? 98  LEU   R CD1 1 
ATOM   6706 C CD2 . LEU   E 5 248 ? 115.149 109.108 150.480 1.00 72.48  ? 98  LEU   R CD2 1 
ATOM   6707 N N   . VAL   E 5 249 ? 119.751 108.343 152.191 1.00 68.19  ? 99  VAL   R N   1 
ATOM   6708 C CA  . VAL   E 5 249 ? 120.584 109.414 152.734 1.00 68.19  ? 99  VAL   R CA  1 
ATOM   6709 C C   . VAL   E 5 249 ? 121.933 109.439 152.044 1.00 68.19  ? 99  VAL   R C   1 
ATOM   6710 O O   . VAL   E 5 249 ? 122.457 110.506 151.712 1.00 68.19  ? 99  VAL   R O   1 
ATOM   6711 C CB  . VAL   E 5 249 ? 120.736 109.261 154.256 1.00 68.19  ? 99  VAL   R CB  1 
ATOM   6712 C CG1 . VAL   E 5 249 ? 121.792 110.211 154.772 1.00 68.19  ? 99  VAL   R CG1 1 
ATOM   6713 C CG2 . VAL   E 5 249 ? 119.409 109.528 154.944 1.00 68.19  ? 99  VAL   R CG2 1 
ATOM   6714 N N   . SER   E 5 250 ? 122.509 108.272 151.795 1.00 66.10  ? 100 SER   R N   1 
ATOM   6715 C CA  . SER   E 5 250 ? 123.808 108.240 151.135 1.00 66.10  ? 100 SER   R CA  1 
ATOM   6716 C C   . SER   E 5 250 ? 123.707 108.692 149.681 1.00 66.10  ? 100 SER   R C   1 
ATOM   6717 O O   . SER   E 5 250 ? 124.486 109.544 149.215 1.00 66.10  ? 100 SER   R O   1 
ATOM   6718 C CB  . SER   E 5 250 ? 124.404 106.839 151.219 1.00 66.10  ? 100 SER   R CB  1 
ATOM   6719 O OG  . SER   E 5 250 ? 125.590 106.750 150.449 1.00 66.10  ? 100 SER   R OG  1 
ATOM   6720 N N   . VAL   E 5 251 ? 122.750 108.138 148.939 1.00 64.98  ? 101 VAL   R N   1 
ATOM   6721 C CA  . VAL   E 5 251 ? 122.712 108.483 147.529 1.00 64.98  ? 101 VAL   R CA  1 
ATOM   6722 C C   . VAL   E 5 251 ? 122.241 109.921 147.373 1.00 64.98  ? 101 VAL   R C   1 
ATOM   6723 O O   . VAL   E 5 251 ? 122.418 110.526 146.312 1.00 64.98  ? 101 VAL   R O   1 
ATOM   6724 C CB  . VAL   E 5 251 ? 121.846 107.463 146.758 1.00 64.98  ? 101 VAL   R CB  1 
ATOM   6725 C CG1 . VAL   E 5 251 ? 121.775 107.800 145.276 1.00 64.98  ? 101 VAL   R CG1 1 
ATOM   6726 C CG2 . VAL   E 5 251 ? 122.382 106.054 146.962 1.00 64.98  ? 101 VAL   R CG2 1 
ATOM   6727 N N   . MET   E 5 252 ? 121.685 110.507 148.438 1.00 64.29  ? 102 MET   R N   1 
ATOM   6728 C CA  . MET   E 5 252 ? 121.346 111.922 148.463 1.00 64.29  ? 102 MET   R CA  1 
ATOM   6729 C C   . MET   E 5 252 ? 122.531 112.806 148.803 1.00 64.29  ? 102 MET   R C   1 
ATOM   6730 O O   . MET   E 5 252 ? 122.640 113.912 148.268 1.00 64.29  ? 102 MET   R O   1 
ATOM   6731 C CB  . MET   E 5 252 ? 120.229 112.178 149.475 1.00 64.29  ? 102 MET   R CB  1 
ATOM   6732 C CG  . MET   E 5 252 ? 119.763 113.613 149.542 1.00 64.29  ? 102 MET   R CG  1 
ATOM   6733 S SD  . MET   E 5 252 ? 118.432 113.861 150.728 1.00 64.29  ? 102 MET   R SD  1 
ATOM   6734 C CE  . MET   E 5 252 ? 119.318 113.682 152.273 1.00 64.29  ? 102 MET   R CE  1 
ATOM   6735 N N   . THR   E 5 253 ? 123.415 112.367 149.691 1.00 60.28  ? 103 THR   R N   1 
ATOM   6736 C CA  . THR   E 5 253 ? 124.597 113.173 149.947 1.00 60.28  ? 103 THR   R CA  1 
ATOM   6737 C C   . THR   E 5 253 ? 125.608 113.066 148.824 1.00 60.28  ? 103 THR   R C   1 
ATOM   6738 O O   . THR   E 5 253 ? 126.623 113.764 148.863 1.00 60.28  ? 103 THR   R O   1 
ATOM   6739 C CB  . THR   E 5 253 ? 125.266 112.801 151.274 1.00 60.28  ? 103 THR   R CB  1 
ATOM   6740 O OG1 . THR   E 5 253 ? 126.464 113.567 151.429 1.00 60.28  ? 103 THR   R OG1 1 
ATOM   6741 C CG2 . THR   E 5 253 ? 125.635 111.345 151.316 1.00 60.28  ? 103 THR   R CG2 1 
ATOM   6742 N N   . PHE   E 5 254 ? 125.375 112.198 147.851 1.00 60.69  ? 104 PHE   R N   1 
ATOM   6743 C CA  . PHE   E 5 254 ? 126.248 112.218 146.678 1.00 60.69  ? 104 PHE   R CA  1 
ATOM   6744 C C   . PHE   E 5 254 ? 126.203 113.550 145.924 1.00 60.69  ? 104 PHE   R C   1 
ATOM   6745 O O   . PHE   E 5 254 ? 127.273 114.152 145.730 1.00 60.69  ? 104 PHE   R O   1 
ATOM   6746 C CB  . PHE   E 5 254 ? 125.916 111.034 145.763 1.00 60.69  ? 104 PHE   R CB  1 
ATOM   6747 C CG  . PHE   E 5 254 ? 126.430 111.177 144.357 1.00 60.69  ? 104 PHE   R CG  1 
ATOM   6748 C CD1 . PHE   E 5 254 ? 127.711 111.642 144.105 1.00 60.69  ? 104 PHE   R CD1 1 
ATOM   6749 C CD2 . PHE   E 5 254 ? 125.623 110.848 143.282 1.00 60.69  ? 104 PHE   R CD2 1 
ATOM   6750 C CE1 . PHE   E 5 254 ? 128.175 111.767 142.820 1.00 60.69  ? 104 PHE   R CE1 1 
ATOM   6751 C CE2 . PHE   E 5 254 ? 126.085 110.976 141.989 1.00 60.69  ? 104 PHE   R CE2 1 
ATOM   6752 C CZ  . PHE   E 5 254 ? 127.363 111.437 141.759 1.00 60.69  ? 104 PHE   R CZ  1 
ATOM   6753 N N   . PRO   E 5 255 ? 125.050 114.072 145.480 1.00 58.58  ? 105 PRO   R N   1 
ATOM   6754 C CA  . PRO   E 5 255 ? 125.072 115.313 144.676 1.00 58.58  ? 105 PRO   R CA  1 
ATOM   6755 C C   . PRO   E 5 255 ? 125.412 116.584 145.455 1.00 58.58  ? 105 PRO   R C   1 
ATOM   6756 O O   . PRO   E 5 255 ? 125.816 117.582 144.836 1.00 58.58  ? 105 PRO   R O   1 
ATOM   6757 C CB  . PRO   E 5 255 ? 123.651 115.389 144.112 1.00 58.58  ? 105 PRO   R CB  1 
ATOM   6758 C CG  . PRO   E 5 255 ? 123.108 114.027 144.245 1.00 58.58  ? 105 PRO   R CG  1 
ATOM   6759 C CD  . PRO   E 5 255 ? 123.711 113.474 145.480 1.00 58.58  ? 105 PRO   R CD  1 
ATOM   6760 N N   . TYR   E 5 256 ? 125.241 116.586 146.778 1.00 54.58  ? 106 TYR   R N   1 
ATOM   6761 C CA  . TYR   E 5 256 ? 125.577 117.749 147.589 1.00 54.58  ? 106 TYR   R CA  1 
ATOM   6762 C C   . TYR   E 5 256 ? 127.025 118.158 147.409 1.00 54.58  ? 106 TYR   R C   1 
ATOM   6763 O O   . TYR   E 5 256 ? 127.339 119.357 147.387 1.00 54.58  ? 106 TYR   R O   1 
ATOM   6764 C CB  . TYR   E 5 256 ? 125.298 117.422 149.046 1.00 54.58  ? 106 TYR   R CB  1 
ATOM   6765 C CG  . TYR   E 5 256 ? 125.303 118.558 150.021 1.00 54.58  ? 106 TYR   R CG  1 
ATOM   6766 C CD1 . TYR   E 5 256 ? 124.245 119.426 150.098 1.00 54.58  ? 106 TYR   R CD1 1 
ATOM   6767 C CD2 . TYR   E 5 256 ? 126.336 118.707 150.920 1.00 54.58  ? 106 TYR   R CD2 1 
ATOM   6768 C CE1 . TYR   E 5 256 ? 124.231 120.440 151.009 1.00 54.58  ? 106 TYR   R CE1 1 
ATOM   6769 C CE2 . TYR   E 5 256 ? 126.336 119.712 151.836 1.00 54.58  ? 106 TYR   R CE2 1 
ATOM   6770 C CZ  . TYR   E 5 256 ? 125.281 120.581 151.878 1.00 54.58  ? 106 TYR   R CZ  1 
ATOM   6771 O OH  . TYR   E 5 256 ? 125.265 121.601 152.794 1.00 54.58  ? 106 TYR   R OH  1 
ATOM   6772 N N   . PHE   E 5 257 ? 127.925 117.188 147.276 1.00 56.18  ? 107 PHE   R N   1 
ATOM   6773 C CA  . PHE   E 5 257 ? 129.336 117.528 147.195 1.00 56.18  ? 107 PHE   R CA  1 
ATOM   6774 C C   . PHE   E 5 257 ? 129.676 118.110 145.833 1.00 56.18  ? 107 PHE   R C   1 
ATOM   6775 O O   . PHE   E 5 257 ? 130.499 119.026 145.727 1.00 56.18  ? 107 PHE   R O   1 
ATOM   6776 C CB  . PHE   E 5 257 ? 130.191 116.310 147.524 1.00 56.18  ? 107 PHE   R CB  1 
ATOM   6777 C CG  . PHE   E 5 257 ? 130.358 116.094 148.990 1.00 56.18  ? 107 PHE   R CG  1 
ATOM   6778 C CD1 . PHE   E 5 257 ? 129.996 117.080 149.876 1.00 56.18  ? 107 PHE   R CD1 1 
ATOM   6779 C CD2 . PHE   E 5 257 ? 130.865 114.910 149.485 1.00 56.18  ? 107 PHE   R CD2 1 
ATOM   6780 C CE1 . PHE   E 5 257 ? 130.130 116.899 151.226 1.00 56.18  ? 107 PHE   R CE1 1 
ATOM   6781 C CE2 . PHE   E 5 257 ? 131.007 114.723 150.842 1.00 56.18  ? 107 PHE   R CE2 1 
ATOM   6782 C CZ  . PHE   E 5 257 ? 130.636 115.723 151.713 1.00 56.18  ? 107 PHE   R CZ  1 
ATOM   6783 N N   . THR   E 5 258 ? 129.010 117.632 144.785 1.00 56.89  ? 108 THR   R N   1 
ATOM   6784 C CA  . THR   E 5 258 ? 129.106 118.303 143.495 1.00 56.89  ? 108 THR   R CA  1 
ATOM   6785 C C   . THR   E 5 258 ? 128.652 119.750 143.612 1.00 56.89  ? 108 THR   R C   1 
ATOM   6786 O O   . THR   E 5 258 ? 129.314 120.668 143.112 1.00 56.89  ? 108 THR   R O   1 
ATOM   6787 C CB  . THR   E 5 258 ? 128.263 117.575 142.454 1.00 56.89  ? 108 THR   R CB  1 
ATOM   6788 O OG1 . THR   E 5 258 ? 126.884 117.637 142.833 1.00 56.89  ? 108 THR   R OG1 1 
ATOM   6789 C CG2 . THR   E 5 258 ? 128.673 116.129 142.360 1.00 56.89  ? 108 THR   R CG2 1 
ATOM   6790 N N   . GLY   E 5 259 ? 127.531 119.971 144.292 1.00 51.57  ? 109 GLY   R N   1 
ATOM   6791 C CA  . GLY   E 5 259 ? 127.003 121.315 144.425 1.00 51.57  ? 109 GLY   R CA  1 
ATOM   6792 C C   . GLY   E 5 259 ? 127.949 122.280 145.105 1.00 51.57  ? 109 GLY   R C   1 
ATOM   6793 O O   . GLY   E 5 259 ? 128.208 123.377 144.598 1.00 51.57  ? 109 GLY   R O   1 
ATOM   6794 N N   . LEU   E 5 260 ? 128.495 121.869 146.244 1.00 49.08  ? 110 LEU   R N   1 
ATOM   6795 C CA  . LEU   E 5 260 ? 129.396 122.756 146.974 1.00 49.08  ? 110 LEU   R CA  1 
ATOM   6796 C C   . LEU   E 5 260 ? 130.723 122.932 146.245 1.00 49.08  ? 110 LEU   R C   1 
ATOM   6797 O O   . LEU   E 5 260 ? 131.263 124.046 146.182 1.00 49.08  ? 110 LEU   R O   1 
ATOM   6798 C CB  . LEU   E 5 260 ? 129.610 122.232 148.387 1.00 49.08  ? 110 LEU   R CB  1 
ATOM   6799 C CG  . LEU   E 5 260 ? 128.587 122.674 149.427 1.00 49.08  ? 110 LEU   R CG  1 
ATOM   6800 C CD1 . LEU   E 5 260 ? 127.237 122.037 149.193 1.00 49.08  ? 110 LEU   R CD1 1 
ATOM   6801 C CD2 . LEU   E 5 260 ? 129.101 122.320 150.798 1.00 49.08  ? 110 LEU   R CD2 1 
ATOM   6802 N N   . SER   E 5 261 ? 131.262 121.858 145.671 1.00 52.25  ? 111 SER   R N   1 
ATOM   6803 C CA  . SER   E 5 261 ? 132.485 121.991 144.892 1.00 52.25  ? 111 SER   R CA  1 
ATOM   6804 C C   . SER   E 5 261 ? 132.310 122.978 143.749 1.00 52.25  ? 111 SER   R C   1 
ATOM   6805 O O   . SER   E 5 261 ? 133.223 123.751 143.440 1.00 52.25  ? 111 SER   R O   1 
ATOM   6806 C CB  . SER   E 5 261 ? 132.913 120.633 144.354 1.00 52.25  ? 111 SER   R CB  1 
ATOM   6807 O OG  . SER   E 5 261 ? 133.279 119.767 145.411 1.00 52.25  ? 111 SER   R OG  1 
ATOM   6808 N N   . MET   E 5 262 ? 131.141 122.986 143.117 1.00 51.68  ? 112 MET   R N   1 
ATOM   6809 C CA  . MET   E 5 262 ? 130.941 123.909 142.009 1.00 51.68  ? 112 MET   R CA  1 
ATOM   6810 C C   . MET   E 5 262 ? 130.684 125.329 142.490 1.00 51.68  ? 112 MET   R C   1 
ATOM   6811 O O   . MET   E 5 262 ? 131.098 126.288 141.828 1.00 51.68  ? 112 MET   R O   1 
ATOM   6812 C CB  . MET   E 5 262 ? 129.801 123.414 141.136 1.00 51.68  ? 112 MET   R CB  1 
ATOM   6813 C CG  . MET   E 5 262 ? 130.148 122.136 140.460 1.00 51.68  ? 112 MET   R CG  1 
ATOM   6814 S SD  . MET   E 5 262 ? 131.296 122.320 139.113 1.00 51.68  ? 112 MET   R SD  1 
ATOM   6815 C CE  . MET   E 5 262 ? 130.839 120.883 138.170 1.00 51.68  ? 112 MET   R CE  1 
ATOM   6816 N N   . LEU   E 5 263 ? 130.012 125.486 143.629 1.00 51.39  ? 113 LEU   R N   1 
ATOM   6817 C CA  . LEU   E 5 263 ? 129.874 126.813 144.214 1.00 51.39  ? 113 LEU   R CA  1 
ATOM   6818 C C   . LEU   E 5 263 ? 131.229 127.406 144.546 1.00 51.39  ? 113 LEU   R C   1 
ATOM   6819 O O   . LEU   E 5 263 ? 131.376 128.631 144.604 1.00 51.39  ? 113 LEU   R O   1 
ATOM   6820 C CB  . LEU   E 5 263 ? 129.012 126.755 145.471 1.00 51.39  ? 113 LEU   R CB  1 
ATOM   6821 C CG  . LEU   E 5 263 ? 127.510 126.932 145.298 1.00 51.39  ? 113 LEU   R CG  1 
ATOM   6822 C CD1 . LEU   E 5 263 ? 126.833 127.029 146.648 1.00 51.39  ? 113 LEU   R CD1 1 
ATOM   6823 C CD2 . LEU   E 5 263 ? 127.233 128.151 144.480 1.00 51.39  ? 113 LEU   R CD2 1 
ATOM   6824 N N   . SER   E 5 264 ? 132.222 126.560 144.792 1.00 49.25  ? 114 SER   R N   1 
ATOM   6825 C CA  . SER   E 5 264 ? 133.568 127.076 145.001 1.00 49.25  ? 114 SER   R CA  1 
ATOM   6826 C C   . SER   E 5 264 ? 134.315 127.304 143.693 1.00 49.25  ? 114 SER   R C   1 
ATOM   6827 O O   . SER   E 5 264 ? 135.075 128.275 143.574 1.00 49.25  ? 114 SER   R O   1 
ATOM   6828 C CB  . SER   E 5 264 ? 134.356 126.122 145.880 1.00 49.25  ? 114 SER   R CB  1 
ATOM   6829 O OG  . SER   E 5 264 ? 135.673 126.589 146.066 1.00 49.25  ? 114 SER   R OG  1 
ATOM   6830 N N   . ALA   E 5 265 ? 134.114 126.428 142.710 1.00 49.75  ? 115 ALA   R N   1 
ATOM   6831 C CA  . ALA   E 5 265 ? 134.793 126.578 141.428 1.00 49.75  ? 115 ALA   R CA  1 
ATOM   6832 C C   . ALA   E 5 265 ? 134.365 127.849 140.709 1.00 49.75  ? 115 ALA   R C   1 
ATOM   6833 O O   . ALA   E 5 265 ? 135.194 128.519 140.081 1.00 49.75  ? 115 ALA   R O   1 
ATOM   6834 C CB  . ALA   E 5 265 ? 134.534 125.358 140.549 1.00 49.75  ? 115 ALA   R CB  1 
ATOM   6835 N N   . ILE   E 5 266 ? 133.079 128.199 140.779 1.00 50.08  ? 116 ILE   R N   1 
ATOM   6836 C CA  . ILE   E 5 266 ? 132.615 129.434 140.145 1.00 50.08  ? 116 ILE   R CA  1 
ATOM   6837 C C   . ILE   E 5 266 ? 133.331 130.643 140.731 1.00 50.08  ? 116 ILE   R C   1 
ATOM   6838 O O   . ILE   E 5 266 ? 133.835 131.501 139.997 1.00 50.08  ? 116 ILE   R O   1 
ATOM   6839 C CB  . ILE   E 5 266 ? 131.092 129.582 140.280 1.00 50.08  ? 116 ILE   R CB  1 
ATOM   6840 C CG1 . ILE   E 5 266 ? 130.365 128.580 139.396 1.00 50.08  ? 116 ILE   R CG1 1 
ATOM   6841 C CG2 . ILE   E 5 266 ? 130.669 130.986 139.944 1.00 50.08  ? 116 ILE   R CG2 1 
ATOM   6842 C CD1 . ILE   E 5 266 ? 128.881 128.502 139.660 1.00 50.08  ? 116 ILE   R CD1 1 
ATOM   6843 N N   . SER   E 5 267 ? 133.376 130.738 142.058 1.00 51.07  ? 117 SER   R N   1 
ATOM   6844 C CA  . SER   E 5 267 ? 134.000 131.897 142.686 1.00 51.07  ? 117 SER   R CA  1 
ATOM   6845 C C   . SER   E 5 267 ? 135.490 131.952 142.392 1.00 51.07  ? 117 SER   R C   1 
ATOM   6846 O O   . SER   E 5 267 ? 136.037 133.030 142.140 1.00 51.07  ? 117 SER   R O   1 
ATOM   6847 C CB  . SER   E 5 267 ? 133.752 131.887 144.192 1.00 51.07  ? 117 SER   R CB  1 
ATOM   6848 O OG  . SER   E 5 267 ? 134.561 130.917 144.834 1.00 51.07  ? 117 SER   R OG  1 
ATOM   6849 N N   . THR   E 5 268 ? 136.165 130.804 142.407 1.00 51.16  ? 118 THR   R N   1 
ATOM   6850 C CA  . THR   E 5 268 ? 137.591 130.807 142.096 1.00 51.16  ? 118 THR   R CA  1 
ATOM   6851 C C   . THR   E 5 268 ? 137.859 131.225 140.650 1.00 51.16  ? 118 THR   R C   1 
ATOM   6852 O O   . THR   E 5 268 ? 138.776 132.014 140.388 1.00 51.16  ? 118 THR   R O   1 
ATOM   6853 C CB  . THR   E 5 268 ? 138.191 129.436 142.378 1.00 51.16  ? 118 THR   R CB  1 
ATOM   6854 O OG1 . THR   E 5 268 ? 137.934 129.073 143.740 1.00 51.16  ? 118 THR   R OG1 1 
ATOM   6855 C CG2 . THR   E 5 268 ? 139.686 129.455 142.144 1.00 51.16  ? 118 THR   R CG2 1 
ATOM   6856 N N   . GLU   E 5 269 ? 137.074 130.716 139.695 1.00 52.67  ? 119 GLU   R N   1 
ATOM   6857 C CA  . GLU   E 5 269 ? 137.262 131.120 138.304 1.00 52.67  ? 119 GLU   R CA  1 
ATOM   6858 C C   . GLU   E 5 269 ? 136.949 132.596 138.103 1.00 52.67  ? 119 GLU   R C   1 
ATOM   6859 O O   . GLU   E 5 269 ? 137.623 133.277 137.322 1.00 52.67  ? 119 GLU   R O   1 
ATOM   6860 C CB  . GLU   E 5 269 ? 136.400 130.265 137.384 1.00 52.67  ? 119 GLU   R CB  1 
ATOM   6861 C CG  . GLU   E 5 269 ? 136.891 128.837 137.246 1.00 52.67  ? 119 GLU   R CG  1 
ATOM   6862 C CD  . GLU   E 5 269 ? 138.214 128.741 136.512 1.00 52.67  ? 119 GLU   R CD  1 
ATOM   6863 O OE1 . GLU   E 5 269 ? 138.465 129.580 135.622 1.00 52.67  ? 119 GLU   R OE1 1 
ATOM   6864 O OE2 . GLU   E 5 269 ? 139.004 127.825 136.826 1.00 52.67  ? 119 GLU   R OE2 1 
ATOM   6865 N N   . ARG   E 5 270 ? 135.935 133.112 138.793 1.00 51.65  ? 120 ARG   R N   1 
ATOM   6866 C CA  . ARG   E 5 270 ? 135.632 134.534 138.710 1.00 51.65  ? 120 ARG   R CA  1 
ATOM   6867 C C   . ARG   E 5 270 ? 136.773 135.374 139.279 1.00 51.65  ? 120 ARG   R C   1 
ATOM   6868 O O   . ARG   E 5 270 ? 137.122 136.431 138.731 1.00 51.65  ? 120 ARG   R O   1 
ATOM   6869 C CB  . ARG   E 5 270 ? 134.323 134.803 139.439 1.00 51.65  ? 120 ARG   R CB  1 
ATOM   6870 C CG  . ARG   E 5 270 ? 133.624 136.072 139.069 1.00 51.65  ? 120 ARG   R CG  1 
ATOM   6871 C CD  . ARG   E 5 270 ? 132.492 136.334 140.040 1.00 51.65  ? 120 ARG   R CD  1 
ATOM   6872 N NE  . ARG   E 5 270 ? 131.350 135.447 139.833 1.00 51.65  ? 120 ARG   R NE  1 
ATOM   6873 C CZ  . ARG   E 5 270 ? 130.334 135.323 140.684 1.00 51.65  ? 120 ARG   R CZ  1 
ATOM   6874 N NH1 . ARG   E 5 270 ? 130.313 136.023 141.808 1.00 51.65  ? 120 ARG   R NH1 1 
ATOM   6875 N NH2 . ARG   E 5 270 ? 129.338 134.493 140.411 1.00 51.65  ? 120 ARG   R NH2 1 
ATOM   6876 N N   . CYS   E 5 271 ? 137.375 134.913 140.375 1.00 53.02  ? 121 CYS   R N   1 
ATOM   6877 C CA  . CYS   E 5 271 ? 138.545 135.592 140.923 1.00 53.02  ? 121 CYS   R CA  1 
ATOM   6878 C C   . CYS   E 5 271 ? 139.695 135.595 139.931 1.00 53.02  ? 121 CYS   R C   1 
ATOM   6879 O O   . CYS   E 5 271 ? 140.406 136.597 139.795 1.00 53.02  ? 121 CYS   R O   1 
ATOM   6880 C CB  . CYS   E 5 271 ? 138.977 134.932 142.227 1.00 53.02  ? 121 CYS   R CB  1 
ATOM   6881 S SG  . CYS   E 5 271 ? 140.570 135.495 142.836 1.00 53.02  ? 121 CYS   R SG  1 
ATOM   6882 N N   . LEU   E 5 272 ? 139.902 134.477 139.240 1.00 50.34  ? 122 LEU   R N   1 
ATOM   6883 C CA  . LEU   E 5 272 ? 140.902 134.451 138.180 1.00 50.34  ? 122 LEU   R CA  1 
ATOM   6884 C C   . LEU   E 5 272 ? 140.564 135.458 137.091 1.00 50.34  ? 122 LEU   R C   1 
ATOM   6885 O O   . LEU   E 5 272 ? 141.451 136.136 136.564 1.00 50.34  ? 122 LEU   R O   1 
ATOM   6886 C CB  . LEU   E 5 272 ? 141.015 133.048 137.591 1.00 50.34  ? 122 LEU   R CB  1 
ATOM   6887 C CG  . LEU   E 5 272 ? 142.064 132.094 138.160 1.00 50.34  ? 122 LEU   R CG  1 
ATOM   6888 C CD1 . LEU   E 5 272 ? 143.457 132.548 137.784 1.00 50.34  ? 122 LEU   R CD1 1 
ATOM   6889 C CD2 . LEU   E 5 272 ? 141.937 131.960 139.665 1.00 50.34  ? 122 LEU   R CD2 1 
ATOM   6890 N N   . SER   E 5 273 ? 139.285 135.567 136.739 1.00 48.80  ? 123 SER   R N   1 
ATOM   6891 C CA  . SER   E 5 273 ? 138.878 136.469 135.668 1.00 48.80  ? 123 SER   R CA  1 
ATOM   6892 C C   . SER   E 5 273 ? 139.040 137.931 136.034 1.00 48.80  ? 123 SER   R C   1 
ATOM   6893 O O   . SER   E 5 273 ? 139.156 138.767 135.139 1.00 48.80  ? 123 SER   R O   1 
ATOM   6894 C CB  . SER   E 5 273 ? 137.430 136.215 135.279 1.00 48.80  ? 123 SER   R CB  1 
ATOM   6895 O OG  . SER   E 5 273 ? 136.900 137.342 134.609 1.00 48.80  ? 123 SER   R OG  1 
ATOM   6896 N N   . VAL   E 5 274 ? 139.022 138.259 137.317 1.00 50.57  ? 124 VAL   R N   1 
ATOM   6897 C CA  . VAL   E 5 274 ? 139.253 139.639 137.721 1.00 50.57  ? 124 VAL   R CA  1 
ATOM   6898 C C   . VAL   E 5 274 ? 140.728 139.920 138.016 1.00 50.57  ? 124 VAL   R C   1 
ATOM   6899 O O   . VAL   E 5 274 ? 141.186 141.051 137.842 1.00 50.57  ? 124 VAL   R O   1 
ATOM   6900 C CB  . VAL   E 5 274 ? 138.360 139.983 138.919 1.00 50.57  ? 124 VAL   R CB  1 
ATOM   6901 C CG1 . VAL   E 5 274 ? 138.652 141.373 139.431 1.00 50.57  ? 124 VAL   R CG1 1 
ATOM   6902 C CG2 . VAL   E 5 274 ? 136.904 139.883 138.512 1.00 50.57  ? 124 VAL   R CG2 1 
ATOM   6903 N N   . LEU   E 5 275 ? 141.501 138.916 138.425 1.00 52.24  ? 125 LEU   R N   1 
ATOM   6904 C CA  . LEU   E 5 275 ? 142.932 139.126 138.630 1.00 52.24  ? 125 LEU   R CA  1 
ATOM   6905 C C   . LEU   E 5 275 ? 143.676 139.254 137.308 1.00 52.24  ? 125 LEU   R C   1 
ATOM   6906 O O   . LEU   E 5 275 ? 144.526 140.135 137.147 1.00 52.24  ? 125 LEU   R O   1 
ATOM   6907 C CB  . LEU   E 5 275 ? 143.524 137.984 139.447 1.00 52.24  ? 125 LEU   R CB  1 
ATOM   6908 C CG  . LEU   E 5 275 ? 143.491 138.088 140.963 1.00 52.24  ? 125 LEU   R CG  1 
ATOM   6909 C CD1 . LEU   E 5 275 ? 144.166 136.877 141.561 1.00 52.24  ? 125 LEU   R CD1 1 
ATOM   6910 C CD2 . LEU   E 5 275 ? 144.189 139.355 141.409 1.00 52.24  ? 125 LEU   R CD2 1 
ATOM   6911 N N   . TRP   E 5 276 ? 143.375 138.381 136.352 1.00 50.79  ? 126 TRP   R N   1 
ATOM   6912 C CA  . TRP   E 5 276 ? 144.163 138.219 135.130 1.00 50.79  ? 126 TRP   R CA  1 
ATOM   6913 C C   . TRP   E 5 276 ? 143.235 138.244 133.921 1.00 50.79  ? 126 TRP   R C   1 
ATOM   6914 O O   . TRP   E 5 276 ? 142.919 137.193 133.349 1.00 50.79  ? 126 TRP   R O   1 
ATOM   6915 C CB  . TRP   E 5 276 ? 144.953 136.913 135.181 1.00 50.79  ? 126 TRP   R CB  1 
ATOM   6916 C CG  . TRP   E 5 276 ? 146.167 136.960 136.025 1.00 50.79  ? 126 TRP   R CG  1 
ATOM   6917 C CD1 . TRP   E 5 276 ? 147.084 137.961 136.083 1.00 50.79  ? 126 TRP   R CD1 1 
ATOM   6918 C CD2 . TRP   E 5 276 ? 146.624 135.945 136.918 1.00 50.79  ? 126 TRP   R CD2 1 
ATOM   6919 N NE1 . TRP   E 5 276 ? 148.081 137.637 136.966 1.00 50.79  ? 126 TRP   R NE1 1 
ATOM   6920 C CE2 . TRP   E 5 276 ? 147.821 136.400 137.489 1.00 50.79  ? 126 TRP   R CE2 1 
ATOM   6921 C CE3 . TRP   E 5 276 ? 146.136 134.695 137.288 1.00 50.79  ? 126 TRP   R CE3 1 
ATOM   6922 C CZ2 . TRP   E 5 276 ? 148.533 135.653 138.419 1.00 50.79  ? 126 TRP   R CZ2 1 
ATOM   6923 C CZ3 . TRP   E 5 276 ? 146.842 133.954 138.206 1.00 50.79  ? 126 TRP   R CZ3 1 
ATOM   6924 C CH2 . TRP   E 5 276 ? 148.028 134.433 138.762 1.00 50.79  ? 126 TRP   R CH2 1 
ATOM   6925 N N   . PRO   E 5 277 ? 142.778 139.426 133.502 1.00 47.21  ? 127 PRO   R N   1 
ATOM   6926 C CA  . PRO   E 5 277 ? 141.708 139.470 132.492 1.00 47.21  ? 127 PRO   R CA  1 
ATOM   6927 C C   . PRO   E 5 277 ? 142.149 139.065 131.101 1.00 47.21  ? 127 PRO   R C   1 
ATOM   6928 O O   . PRO   E 5 277 ? 141.410 138.359 130.399 1.00 47.21  ? 127 PRO   R O   1 
ATOM   6929 C CB  . PRO   E 5 277 ? 141.258 140.933 132.534 1.00 47.21  ? 127 PRO   R CB  1 
ATOM   6930 C CG  . PRO   E 5 277 ? 141.853 141.495 133.760 1.00 47.21  ? 127 PRO   R CG  1 
ATOM   6931 C CD  . PRO   E 5 277 ? 143.107 140.760 133.995 1.00 47.21  ? 127 PRO   R CD  1 
ATOM   6932 N N   . ILE   E 5 278 ? 143.328 139.510 130.672 1.00 49.50  ? 128 ILE   R N   1 
ATOM   6933 C CA  . ILE   E 5 278 ? 143.815 139.181 129.338 1.00 49.50  ? 128 ILE   R CA  1 
ATOM   6934 C C   . ILE   E 5 278 ? 143.984 137.681 129.193 1.00 49.50  ? 128 ILE   R C   1 
ATOM   6935 O O   . ILE   E 5 278 ? 143.658 137.101 128.150 1.00 49.50  ? 128 ILE   R O   1 
ATOM   6936 C CB  . ILE   E 5 278 ? 145.129 139.920 129.063 1.00 49.50  ? 128 ILE   R CB  1 
ATOM   6937 C CG1 . ILE   E 5 278 ? 144.905 141.417 129.164 1.00 49.50  ? 128 ILE   R CG1 1 
ATOM   6938 C CG2 . ILE   E 5 278 ? 145.652 139.562 127.695 1.00 49.50  ? 128 ILE   R CG2 1 
ATOM   6939 C CD1 . ILE   E 5 278 ? 146.174 142.195 129.199 1.00 49.50  ? 128 ILE   R CD1 1 
ATOM   6940 N N   . TRP   E 5 279 ? 144.501 137.027 130.233 1.00 50.65  ? 129 TRP   R N   1 
ATOM   6941 C CA  . TRP   E 5 279 ? 144.544 135.573 130.240 1.00 50.65  ? 129 TRP   R CA  1 
ATOM   6942 C C   . TRP   E 5 279 ? 143.149 134.993 130.075 1.00 50.65  ? 129 TRP   R C   1 
ATOM   6943 O O   . TRP   E 5 279 ? 142.910 134.155 129.200 1.00 50.65  ? 129 TRP   R O   1 
ATOM   6944 C CB  . TRP   E 5 279 ? 145.184 135.078 131.534 1.00 50.65  ? 129 TRP   R CB  1 
ATOM   6945 C CG  . TRP   E 5 279 ? 145.327 133.601 131.597 1.00 50.65  ? 129 TRP   R CG  1 
ATOM   6946 C CD1 . TRP   E 5 279 ? 146.394 132.875 131.192 1.00 50.65  ? 129 TRP   R CD1 1 
ATOM   6947 C CD2 . TRP   E 5 279 ? 144.370 132.666 132.095 1.00 50.65  ? 129 TRP   R CD2 1 
ATOM   6948 N NE1 . TRP   E 5 279 ? 146.166 131.542 131.400 1.00 50.65  ? 129 TRP   R NE1 1 
ATOM   6949 C CE2 . TRP   E 5 279 ? 144.927 131.389 131.957 1.00 50.65  ? 129 TRP   R CE2 1 
ATOM   6950 C CE3 . TRP   E 5 279 ? 143.092 132.787 132.647 1.00 50.65  ? 129 TRP   R CE3 1 
ATOM   6951 C CZ2 . TRP   E 5 279 ? 144.256 130.238 132.346 1.00 50.65  ? 129 TRP   R CZ2 1 
ATOM   6952 C CZ3 . TRP   E 5 279 ? 142.427 131.641 133.032 1.00 50.65  ? 129 TRP   R CZ3 1 
ATOM   6953 C CH2 . TRP   E 5 279 ? 143.010 130.385 132.880 1.00 50.65  ? 129 TRP   R CH2 1 
ATOM   6954 N N   . TYR   E 5 280 ? 142.207 135.443 130.896 1.00 51.94  ? 130 TYR   R N   1 
ATOM   6955 C CA  . TYR   E 5 280 ? 140.898 134.814 130.911 1.00 51.94  ? 130 TYR   R CA  1 
ATOM   6956 C C   . TYR   E 5 280 ? 140.147 134.994 129.607 1.00 51.94  ? 130 TYR   R C   1 
ATOM   6957 O O   . TYR   E 5 280 ? 139.256 134.197 129.311 1.00 51.94  ? 130 TYR   R O   1 
ATOM   6958 C CB  . TYR   E 5 280 ? 140.064 135.362 132.058 1.00 51.94  ? 130 TYR   R CB  1 
ATOM   6959 C CG  . TYR   E 5 280 ? 139.068 134.370 132.574 1.00 51.94  ? 130 TYR   R CG  1 
ATOM   6960 C CD1 . TYR   E 5 280 ? 139.387 133.532 133.625 1.00 51.94  ? 130 TYR   R CD1 1 
ATOM   6961 C CD2 . TYR   E 5 280 ? 137.816 134.258 132.000 1.00 51.94  ? 130 TYR   R CD2 1 
ATOM   6962 C CE1 . TYR   E 5 280 ? 138.484 132.615 134.098 1.00 51.94  ? 130 TYR   R CE1 1 
ATOM   6963 C CE2 . TYR   E 5 280 ? 136.910 133.347 132.463 1.00 51.94  ? 130 TYR   R CE2 1 
ATOM   6964 C CZ  . TYR   E 5 280 ? 137.244 132.525 133.514 1.00 51.94  ? 130 TYR   R CZ  1 
ATOM   6965 O OH  . TYR   E 5 280 ? 136.332 131.608 133.984 1.00 51.94  ? 130 TYR   R OH  1 
ATOM   6966 N N   . ARG   E 5 281 ? 140.474 136.012 128.823 1.00 53.96  ? 131 ARG   R N   1 
ATOM   6967 C CA  . ARG   E 5 281 ? 139.781 136.228 127.563 1.00 53.96  ? 131 ARG   R CA  1 
ATOM   6968 C C   . ARG   E 5 281 ? 140.620 135.914 126.338 1.00 53.96  ? 131 ARG   R C   1 
ATOM   6969 O O   . ARG   E 5 281 ? 140.113 136.038 125.221 1.00 53.96  ? 131 ARG   R O   1 
ATOM   6970 C CB  . ARG   E 5 281 ? 139.267 137.667 127.470 1.00 53.96  ? 131 ARG   R CB  1 
ATOM   6971 C CG  . ARG   E 5 281 ? 138.096 137.952 128.384 1.00 53.96  ? 131 ARG   R CG  1 
ATOM   6972 C CD  . ARG   E 5 281 ? 137.253 139.112 127.885 1.00 53.96  ? 131 ARG   R CD  1 
ATOM   6973 N NE  . ARG   E 5 281 ? 136.400 138.742 126.766 1.00 53.96  ? 131 ARG   R NE  1 
ATOM   6974 C CZ  . ARG   E 5 281 ? 136.671 139.040 125.502 1.00 53.96  ? 131 ARG   R CZ  1 
ATOM   6975 N NH1 . ARG   E 5 281 ? 135.842 138.666 124.536 1.00 53.96  ? 131 ARG   R NH1 1 
ATOM   6976 N NH2 . ARG   E 5 281 ? 137.772 139.714 125.202 1.00 53.96  ? 131 ARG   R NH2 1 
ATOM   6977 N N   . CYS   E 5 282 ? 141.864 135.522 126.496 1.00 60.22  ? 132 CYS   R N   1 
ATOM   6978 C CA  . CYS   E 5 282 ? 142.621 135.306 125.271 1.00 60.22  ? 132 CYS   R CA  1 
ATOM   6979 C C   . CYS   E 5 282 ? 143.347 133.970 125.213 1.00 60.22  ? 132 CYS   R C   1 
ATOM   6980 O O   . CYS   E 5 282 ? 143.401 133.358 124.144 1.00 60.22  ? 132 CYS   R O   1 
ATOM   6981 C CB  . CYS   E 5 282 ? 143.626 136.447 125.086 1.00 60.22  ? 132 CYS   R CB  1 
ATOM   6982 S SG  . CYS   E 5 282 ? 142.887 138.010 124.559 1.00 60.22  ? 132 CYS   R SG  1 
ATOM   6983 N N   . ARG   E 5 283 ? 143.900 133.500 126.326 1.00 57.09  ? 133 ARG   R N   1 
ATOM   6984 C CA  . ARG   E 5 283 ? 144.851 132.393 126.328 1.00 57.09  ? 133 ARG   R CA  1 
ATOM   6985 C C   . ARG   E 5 283 ? 144.390 131.291 127.264 1.00 57.09  ? 133 ARG   R C   1 
ATOM   6986 O O   . ARG   E 5 283 ? 145.138 130.798 128.108 1.00 57.09  ? 133 ARG   R O   1 
ATOM   6987 C CB  . ARG   E 5 283 ? 146.238 132.880 126.720 1.00 57.09  ? 133 ARG   R CB  1 
ATOM   6988 C CG  . ARG   E 5 283 ? 146.738 134.024 125.879 1.00 57.09  ? 133 ARG   R CG  1 
ATOM   6989 C CD  . ARG   E 5 283 ? 148.154 134.376 126.237 1.00 57.09  ? 133 ARG   R CD  1 
ATOM   6990 N NE  . ARG   E 5 283 ? 148.212 135.536 127.111 1.00 57.09  ? 133 ARG   R NE  1 
ATOM   6991 C CZ  . ARG   E 5 283 ? 148.723 135.520 128.335 1.00 57.09  ? 133 ARG   R CZ  1 
ATOM   6992 N NH1 . ARG   E 5 283 ? 149.224 134.398 128.830 1.00 57.09  ? 133 ARG   R NH1 1 
ATOM   6993 N NH2 . ARG   E 5 283 ? 148.735 136.626 129.065 1.00 57.09  ? 133 ARG   R NH2 1 
ATOM   6994 N N   . ARG   E 5 284 ? 143.135 130.891 127.125 1.00 59.29  ? 134 ARG   R N   1 
ATOM   6995 C CA  . ARG   E 5 284 ? 142.552 129.892 127.990 1.00 59.29  ? 134 ARG   R CA  1 
ATOM   6996 C C   . ARG   E 5 284 ? 142.083 128.702 127.166 1.00 59.29  ? 134 ARG   R C   1 
ATOM   6997 O O   . ARG   E 5 284 ? 141.430 128.893 126.130 1.00 59.29  ? 134 ARG   R O   1 
ATOM   6998 C CB  . ARG   E 5 284 ? 141.380 130.483 128.757 1.00 59.29  ? 134 ARG   R CB  1 
ATOM   6999 C CG  . ARG   E 5 284 ? 140.587 129.499 129.555 1.00 59.29  ? 134 ARG   R CG  1 
ATOM   7000 C CD  . ARG   E 5 284 ? 139.599 130.240 130.406 1.00 59.29  ? 134 ARG   R CD  1 
ATOM   7001 N NE  . ARG   E 5 284 ? 138.646 129.347 131.041 1.00 59.29  ? 134 ARG   R NE  1 
ATOM   7002 C CZ  . ARG   E 5 284 ? 137.520 128.944 130.472 1.00 59.29  ? 134 ARG   R CZ  1 
ATOM   7003 N NH1 . ARG   E 5 284 ? 137.211 129.359 129.253 1.00 59.29  ? 134 ARG   R NH1 1 
ATOM   7004 N NH2 . ARG   E 5 284 ? 136.704 128.127 131.120 1.00 59.29  ? 134 ARG   R NH2 1 
ATOM   7005 N N   . PRO   E 5 285 ? 142.403 127.473 127.570 1.00 62.46  ? 135 PRO   R N   1 
ATOM   7006 C CA  . PRO   E 5 285 ? 141.870 126.308 126.862 1.00 62.46  ? 135 PRO   R CA  1 
ATOM   7007 C C   . PRO   E 5 285 ? 140.353 126.294 126.915 1.00 62.46  ? 135 PRO   R C   1 
ATOM   7008 O O   . PRO   E 5 285 ? 139.748 126.623 127.936 1.00 62.46  ? 135 PRO   R O   1 
ATOM   7009 C CB  . PRO   E 5 285 ? 142.474 125.125 127.622 1.00 62.46  ? 135 PRO   R CB  1 
ATOM   7010 C CG  . PRO   E 5 285 ? 142.885 125.685 128.941 1.00 62.46  ? 135 PRO   R CG  1 
ATOM   7011 C CD  . PRO   E 5 285 ? 143.284 127.088 128.680 1.00 62.46  ? 135 PRO   R CD  1 
ATOM   7012 N N   . THR   E 5 286 ? 139.737 125.906 125.799 1.00 69.64  ? 136 THR   R N   1 
ATOM   7013 C CA  . THR   E 5 286 ? 138.283 125.971 125.714 1.00 69.64  ? 136 THR   R CA  1 
ATOM   7014 C C   . THR   E 5 286 ? 137.623 124.878 126.544 1.00 69.64  ? 136 THR   R C   1 
ATOM   7015 O O   . THR   E 5 286 ? 136.588 125.113 127.179 1.00 69.64  ? 136 THR   R O   1 
ATOM   7016 C CB  . THR   E 5 286 ? 137.834 125.877 124.261 1.00 69.64  ? 136 THR   R CB  1 
ATOM   7017 O OG1 . THR   E 5 286 ? 138.684 126.693 123.447 1.00 69.64  ? 136 THR   R OG1 1 
ATOM   7018 C CG2 . THR   E 5 286 ? 136.400 126.362 124.127 1.00 69.64  ? 136 THR   R CG2 1 
ATOM   7019 N N   . HIS   E 5 287 ? 138.202 123.681 126.555 1.00 71.53  ? 137 HIS   R N   1 
ATOM   7020 C CA  . HIS   E 5 287 ? 137.630 122.552 127.271 1.00 71.53  ? 137 HIS   R CA  1 
ATOM   7021 C C   . HIS   E 5 287 ? 138.072 122.487 128.723 1.00 71.53  ? 137 HIS   R C   1 
ATOM   7022 O O   . HIS   E 5 287 ? 137.847 121.464 129.382 1.00 71.53  ? 137 HIS   R O   1 
ATOM   7023 C CB  . HIS   E 5 287 ? 137.985 121.249 126.559 1.00 71.53  ? 137 HIS   R CB  1 
ATOM   7024 C CG  . HIS   E 5 287 ? 137.289 121.071 125.248 1.00 71.53  ? 137 HIS   R CG  1 
ATOM   7025 N ND1 . HIS   E 5 287 ? 136.033 121.580 124.998 1.00 71.53  ? 137 HIS   R ND1 1 
ATOM   7026 C CD2 . HIS   E 5 287 ? 137.671 120.439 124.114 1.00 71.53  ? 137 HIS   R CD2 1 
ATOM   7027 C CE1 . HIS   E 5 287 ? 135.672 121.271 123.765 1.00 71.53  ? 137 HIS   R CE1 1 
ATOM   7028 N NE2 . HIS   E 5 287 ? 136.648 120.579 123.207 1.00 71.53  ? 137 HIS   R NE2 1 
ATOM   7029 N N   . LEU   E 5 288 ? 138.704 123.543 129.236 1.00 65.13  ? 138 LEU   R N   1 
ATOM   7030 C CA  . LEU   E 5 288 ? 139.145 123.529 130.625 1.00 65.13  ? 138 LEU   R CA  1 
ATOM   7031 C C   . LEU   E 5 288 ? 137.957 123.494 131.575 1.00 65.13  ? 138 LEU   R C   1 
ATOM   7032 O O   . LEU   E 5 288 ? 138.021 122.864 132.636 1.00 65.13  ? 138 LEU   R O   1 
ATOM   7033 C CB  . LEU   E 5 288 ? 140.024 124.740 130.912 1.00 65.13  ? 138 LEU   R CB  1 
ATOM   7034 C CG  . LEU   E 5 288 ? 140.500 124.880 132.356 1.00 65.13  ? 138 LEU   R CG  1 
ATOM   7035 C CD1 . LEU   E 5 288 ? 141.219 123.620 132.797 1.00 65.13  ? 138 LEU   R CD1 1 
ATOM   7036 C CD2 . LEU   E 5 288 ? 141.397 126.089 132.514 1.00 65.13  ? 138 LEU   R CD2 1 
ATOM   7037 N N   . SER   E 5 289 ? 136.864 124.162 131.207 1.00 66.19  ? 139 SER   R N   1 
ATOM   7038 C CA  . SER   E 5 289 ? 135.665 124.108 132.030 1.00 66.19  ? 139 SER   R CA  1 
ATOM   7039 C C   . SER   E 5 289 ? 135.141 122.683 132.125 1.00 66.19  ? 139 SER   R C   1 
ATOM   7040 O O   . SER   E 5 289 ? 134.808 122.202 133.215 1.00 66.19  ? 139 SER   R O   1 
ATOM   7041 C CB  . SER   E 5 289 ? 134.600 125.043 131.461 1.00 66.19  ? 139 SER   R CB  1 
ATOM   7042 O OG  . SER   E 5 289 ? 133.411 124.978 132.226 1.00 66.19  ? 139 SER   R OG  1 
ATOM   7043 N N   . ALA   E 5 290 ? 135.082 121.984 130.989 1.00 66.70  ? 140 ALA   R N   1 
ATOM   7044 C CA  . ALA   E 5 290 ? 134.625 120.598 130.994 1.00 66.70  ? 140 ALA   R CA  1 
ATOM   7045 C C   . ALA   E 5 290 ? 135.557 119.716 131.812 1.00 66.70  ? 140 ALA   R C   1 
ATOM   7046 O O   . ALA   E 5 290 ? 135.100 118.872 132.589 1.00 66.70  ? 140 ALA   R O   1 
ATOM   7047 C CB  . ALA   E 5 290 ? 134.508 120.076 129.563 1.00 66.70  ? 140 ALA   R CB  1 
ATOM   7048 N N   . VAL   E 5 291 ? 136.867 119.904 131.658 1.00 67.16  ? 141 VAL   R N   1 
ATOM   7049 C CA  . VAL   E 5 291 ? 137.822 119.085 132.397 1.00 67.16  ? 141 VAL   R CA  1 
ATOM   7050 C C   . VAL   E 5 291 ? 137.631 119.270 133.896 1.00 67.16  ? 141 VAL   R C   1 
ATOM   7051 O O   . VAL   E 5 291 ? 137.486 118.296 134.645 1.00 67.16  ? 141 VAL   R O   1 
ATOM   7052 C CB  . VAL   E 5 291 ? 139.261 119.418 131.967 1.00 67.16  ? 141 VAL   R CB  1 
ATOM   7053 C CG1 . VAL   E 5 291 ? 140.253 118.892 132.989 1.00 67.16  ? 141 VAL   R CG1 1 
ATOM   7054 C CG2 . VAL   E 5 291 ? 139.548 118.838 130.591 1.00 67.16  ? 141 VAL   R CG2 1 
ATOM   7055 N N   . VAL   E 5 292 ? 137.596 120.522 134.352 1.00 65.29  ? 142 VAL   R N   1 
ATOM   7056 C CA  . VAL   E 5 292 ? 137.467 120.780 135.782 1.00 65.29  ? 142 VAL   R CA  1 
ATOM   7057 C C   . VAL   E 5 292 ? 136.129 120.281 136.303 1.00 65.29  ? 142 VAL   R C   1 
ATOM   7058 O O   . VAL   E 5 292 ? 136.053 119.709 137.395 1.00 65.29  ? 142 VAL   R O   1 
ATOM   7059 C CB  . VAL   E 5 292 ? 137.667 122.274 136.082 1.00 65.29  ? 142 VAL   R CB  1 
ATOM   7060 C CG1 . VAL   E 5 292 ? 137.427 122.555 137.554 1.00 65.29  ? 142 VAL   R CG1 1 
ATOM   7061 C CG2 . VAL   E 5 292 ? 139.067 122.709 135.680 1.00 65.29  ? 142 VAL   R CG2 1 
ATOM   7062 N N   . CYS   E 5 293 ? 135.054 120.464 135.532 1.00 67.18  ? 143 CYS   R N   1 
ATOM   7063 C CA  . CYS   E 5 293 ? 133.743 120.081 136.041 1.00 67.18  ? 143 CYS   R CA  1 
ATOM   7064 C C   . CYS   E 5 293 ? 133.601 118.569 136.125 1.00 67.18  ? 143 CYS   R C   1 
ATOM   7065 O O   . CYS   E 5 293 ? 133.066 118.049 137.109 1.00 67.18  ? 143 CYS   R O   1 
ATOM   7066 C CB  . CYS   E 5 293 ? 132.632 120.670 135.176 1.00 67.18  ? 143 CYS   R CB  1 
ATOM   7067 S SG  . CYS   E 5 293 ? 132.463 119.963 133.540 1.00 67.18  ? 143 CYS   R SG  1 
ATOM   7068 N N   . VAL   E 5 294 ? 134.068 117.840 135.109 1.00 67.08  ? 144 VAL   R N   1 
ATOM   7069 C CA  . VAL   E 5 294 ? 133.969 116.386 135.168 1.00 67.08  ? 144 VAL   R CA  1 
ATOM   7070 C C   . VAL   E 5 294 ? 134.896 115.835 136.242 1.00 67.08  ? 144 VAL   R C   1 
ATOM   7071 O O   . VAL   E 5 294 ? 134.560 114.861 136.924 1.00 67.08  ? 144 VAL   R O   1 
ATOM   7072 C CB  . VAL   E 5 294 ? 134.239 115.758 133.786 1.00 67.08  ? 144 VAL   R CB  1 
ATOM   7073 C CG1 . VAL   E 5 294 ? 135.709 115.853 133.401 1.00 67.08  ? 144 VAL   R CG1 1 
ATOM   7074 C CG2 . VAL   E 5 294 ? 133.770 114.311 133.768 1.00 67.08  ? 144 VAL   R CG2 1 
ATOM   7075 N N   . LEU   E 5 295 ? 136.070 116.445 136.421 1.00 66.73  ? 145 LEU   R N   1 
ATOM   7076 C CA  . LEU   E 5 295 ? 136.957 115.998 137.485 1.00 66.73  ? 145 LEU   R CA  1 
ATOM   7077 C C   . LEU   E 5 295 ? 136.318 116.216 138.849 1.00 66.73  ? 145 LEU   R C   1 
ATOM   7078 O O   . LEU   E 5 295 ? 136.434 115.365 139.737 1.00 66.73  ? 145 LEU   R O   1 
ATOM   7079 C CB  . LEU   E 5 295 ? 138.299 116.716 137.377 1.00 66.73  ? 145 LEU   R CB  1 
ATOM   7080 C CG  . LEU   E 5 295 ? 139.448 116.240 138.262 1.00 66.73  ? 145 LEU   R CG  1 
ATOM   7081 C CD1 . LEU   E 5 295 ? 140.763 116.495 137.559 1.00 66.73  ? 145 LEU   R CD1 1 
ATOM   7082 C CD2 . LEU   E 5 295 ? 139.440 116.948 139.603 1.00 66.73  ? 145 LEU   R CD2 1 
ATOM   7083 N N   . LEU   E 5 296 ? 135.632 117.347 139.034 1.00 67.22  ? 146 LEU   R N   1 
ATOM   7084 C CA  . LEU   E 5 296 ? 134.917 117.573 140.286 1.00 67.22  ? 146 LEU   R CA  1 
ATOM   7085 C C   . LEU   E 5 296 ? 133.783 116.575 140.463 1.00 67.22  ? 146 LEU   R C   1 
ATOM   7086 O O   . LEU   E 5 296 ? 133.588 116.041 141.562 1.00 67.22  ? 146 LEU   R O   1 
ATOM   7087 C CB  . LEU   E 5 296 ? 134.387 119.002 140.343 1.00 67.22  ? 146 LEU   R CB  1 
ATOM   7088 C CG  . LEU   E 5 296 ? 135.388 120.037 140.847 1.00 67.22  ? 146 LEU   R CG  1 
ATOM   7089 C CD1 . LEU   E 5 296 ? 134.721 121.392 141.031 1.00 67.22  ? 146 LEU   R CD1 1 
ATOM   7090 C CD2 . LEU   E 5 296 ? 136.017 119.562 142.144 1.00 67.22  ? 146 LEU   R CD2 1 
ATOM   7091 N N   . TRP   E 5 297 ? 133.030 116.304 139.396 1.00 66.08  ? 147 TRP   R N   1 
ATOM   7092 C CA  . TRP   E 5 297 ? 131.958 115.319 139.481 1.00 66.08  ? 147 TRP   R CA  1 
ATOM   7093 C C   . TRP   E 5 297 ? 132.503 113.963 139.907 1.00 66.08  ? 147 TRP   R C   1 
ATOM   7094 O O   . TRP   E 5 297 ? 131.918 113.286 140.760 1.00 66.08  ? 147 TRP   R O   1 
ATOM   7095 C CB  . TRP   E 5 297 ? 131.246 115.197 138.137 1.00 66.08  ? 147 TRP   R CB  1 
ATOM   7096 C CG  . TRP   E 5 297 ? 130.093 116.121 137.933 1.00 66.08  ? 147 TRP   R CG  1 
ATOM   7097 C CD1 . TRP   E 5 297 ? 130.091 117.273 137.211 1.00 66.08  ? 147 TRP   R CD1 1 
ATOM   7098 C CD2 . TRP   E 5 297 ? 128.757 115.946 138.408 1.00 66.08  ? 147 TRP   R CD2 1 
ATOM   7099 N NE1 . TRP   E 5 297 ? 128.845 117.839 137.225 1.00 66.08  ? 147 TRP   R NE1 1 
ATOM   7100 C CE2 . TRP   E 5 297 ? 128.006 117.040 137.951 1.00 66.08  ? 147 TRP   R CE2 1 
ATOM   7101 C CE3 . TRP   E 5 297 ? 128.124 114.973 139.180 1.00 66.08  ? 147 TRP   R CE3 1 
ATOM   7102 C CZ2 . TRP   E 5 297 ? 126.660 117.194 138.249 1.00 66.08  ? 147 TRP   R CZ2 1 
ATOM   7103 C CZ3 . TRP   E 5 297 ? 126.787 115.129 139.474 1.00 66.08  ? 147 TRP   R CZ3 1 
ATOM   7104 C CH2 . TRP   E 5 297 ? 126.071 116.229 139.010 1.00 66.08  ? 147 TRP   R CH2 1 
ATOM   7105 N N   . GLY   E 5 298 ? 133.629 113.554 139.323 1.00 70.87  ? 148 GLY   R N   1 
ATOM   7106 C CA  . GLY   E 5 298 ? 134.224 112.282 139.693 1.00 70.87  ? 148 GLY   R CA  1 
ATOM   7107 C C   . GLY   E 5 298 ? 134.747 112.268 141.115 1.00 70.87  ? 148 GLY   R C   1 
ATOM   7108 O O   . GLY   E 5 298 ? 134.509 111.318 141.861 1.00 70.87  ? 148 GLY   R O   1 
ATOM   7109 N N   . LEU   E 5 299 ? 135.457 113.322 141.515 1.00 70.79  ? 149 LEU   R N   1 
ATOM   7110 C CA  . LEU   E 5 299 ? 136.002 113.383 142.864 1.00 70.79  ? 149 LEU   R CA  1 
ATOM   7111 C C   . LEU   E 5 299 ? 134.899 113.397 143.910 1.00 70.79  ? 149 LEU   R C   1 
ATOM   7112 O O   . LEU   E 5 299 ? 135.119 112.941 145.044 1.00 70.79  ? 149 LEU   R O   1 
ATOM   7113 C CB  . LEU   E 5 299 ? 136.898 114.616 142.977 1.00 70.79  ? 149 LEU   R CB  1 
ATOM   7114 C CG  . LEU   E 5 299 ? 137.846 114.903 144.140 1.00 70.79  ? 149 LEU   R CG  1 
ATOM   7115 C CD1 . LEU   E 5 299 ? 138.669 116.121 143.772 1.00 70.79  ? 149 LEU   R CD1 1 
ATOM   7116 C CD2 . LEU   E 5 299 ? 137.104 115.196 145.414 1.00 70.79  ? 149 LEU   R CD2 1 
ATOM   7117 N N   . SER   E 5 300 ? 133.717 113.887 143.533 1.00 71.52  ? 150 SER   R N   1 
ATOM   7118 C CA  . SER   E 5 300 ? 132.583 113.916 144.443 1.00 71.52  ? 150 SER   R CA  1 
ATOM   7119 C C   . SER   E 5 300 ? 132.344 112.556 145.086 1.00 71.52  ? 150 SER   R C   1 
ATOM   7120 O O   . SER   E 5 300 ? 132.467 112.416 146.301 1.00 71.52  ? 150 SER   R O   1 
ATOM   7121 C CB  . SER   E 5 300 ? 131.333 114.385 143.702 1.00 71.52  ? 150 SER   R CB  1 
ATOM   7122 O OG  . SER   E 5 300 ? 130.160 114.048 144.423 1.00 71.52  ? 150 SER   R OG  1 
ATOM   7123 N N   . LEU   E 5 301 ? 132.018 111.531 144.290 1.00 73.80  ? 151 LEU   R N   1 
ATOM   7124 C CA  . LEU   E 5 301 ? 131.649 110.260 144.909 1.00 73.80  ? 151 LEU   R CA  1 
ATOM   7125 C C   . LEU   E 5 301 ? 132.849 109.566 145.536 1.00 73.80  ? 151 LEU   R C   1 
ATOM   7126 O O   . LEU   E 5 301 ? 132.697 108.892 146.562 1.00 73.80  ? 151 LEU   R O   1 
ATOM   7127 C CB  . LEU   E 5 301 ? 130.963 109.323 143.913 1.00 73.80  ? 151 LEU   R CB  1 
ATOM   7128 C CG  . LEU   E 5 301 ? 131.712 108.609 142.790 1.00 73.80  ? 151 LEU   R CG  1 
ATOM   7129 C CD1 . LEU   E 5 301 ? 130.846 107.490 142.246 1.00 73.80  ? 151 LEU   R CD1 1 
ATOM   7130 C CD2 . LEU   E 5 301 ? 132.033 109.572 141.674 1.00 73.80  ? 151 LEU   R CD2 1 
ATOM   7131 N N   . LEU   E 5 302 ? 134.043 109.745 144.965 1.00 73.55  ? 152 LEU   R N   1 
ATOM   7132 C CA  . LEU   E 5 302 ? 135.234 109.119 145.530 1.00 73.55  ? 152 LEU   R CA  1 
ATOM   7133 C C   . LEU   E 5 302 ? 135.476 109.574 146.959 1.00 73.55  ? 152 LEU   R C   1 
ATOM   7134 O O   . LEU   E 5 302 ? 135.761 108.754 147.838 1.00 73.55  ? 152 LEU   R O   1 
ATOM   7135 C CB  . LEU   E 5 302 ? 136.456 109.404 144.657 1.00 73.55  ? 152 LEU   R CB  1 
ATOM   7136 C CG  . LEU   E 5 302 ? 136.736 108.417 143.520 1.00 73.55  ? 152 LEU   R CG  1 
ATOM   7137 C CD1 . LEU   E 5 302 ? 135.716 108.506 142.399 1.00 73.55  ? 152 LEU   R CD1 1 
ATOM   7138 C CD2 . LEU   E 5 302 ? 138.145 108.633 142.983 1.00 73.55  ? 152 LEU   R CD2 1 
ATOM   7139 N N   . PHE   E 5 303 ? 135.372 110.870 147.219 1.00 74.14  ? 153 PHE   R N   1 
ATOM   7140 C CA  . PHE   E 5 303 ? 135.452 111.330 148.600 1.00 74.14  ? 153 PHE   R CA  1 
ATOM   7141 C C   . PHE   E 5 303 ? 134.092 111.479 149.266 1.00 74.14  ? 153 PHE   R C   1 
ATOM   7142 O O   . PHE   E 5 303 ? 134.014 112.031 150.367 1.00 74.14  ? 153 PHE   R O   1 
ATOM   7143 C CB  . PHE   E 5 303 ? 136.246 112.638 148.690 1.00 74.14  ? 153 PHE   R CB  1 
ATOM   7144 C CG  . PHE   E 5 303 ? 137.719 112.464 148.435 1.00 74.14  ? 153 PHE   R CG  1 
ATOM   7145 C CD1 . PHE   E 5 303 ? 138.556 112.029 149.449 1.00 74.14  ? 153 PHE   R CD1 1 
ATOM   7146 C CD2 . PHE   E 5 303 ? 138.259 112.686 147.184 1.00 74.14  ? 153 PHE   R CD2 1 
ATOM   7147 C CE1 . PHE   E 5 303 ? 139.909 111.854 149.226 1.00 74.14  ? 153 PHE   R CE1 1 
ATOM   7148 C CE2 . PHE   E 5 303 ? 139.612 112.513 146.952 1.00 74.14  ? 153 PHE   R CE2 1 
ATOM   7149 C CZ  . PHE   E 5 303 ? 140.437 112.095 147.974 1.00 74.14  ? 153 PHE   R CZ  1 
ATOM   7150 N N   . SER   E 5 304 ? 133.027 111.011 148.631 1.00 68.62  ? 154 SER   R N   1 
ATOM   7151 C CA  . SER   E 5 304 ? 131.699 111.092 149.211 1.00 68.62  ? 154 SER   R CA  1 
ATOM   7152 C C   . SER   E 5 304 ? 131.231 109.792 149.828 1.00 68.62  ? 154 SER   R C   1 
ATOM   7153 O O   . SER   E 5 304 ? 130.452 109.826 150.784 1.00 68.62  ? 154 SER   R O   1 
ATOM   7154 C CB  . SER   E 5 304 ? 130.688 111.526 148.145 1.00 68.62  ? 154 SER   R CB  1 
ATOM   7155 N N   . MET   E 5 305 ? 131.670 108.649 149.293 1.00 71.84  ? 155 MET   R N   1 
ATOM   7156 C CA  . MET   E 5 305 ? 131.232 107.368 149.839 1.00 71.84  ? 155 MET   R CA  1 
ATOM   7157 C C   . MET   E 5 305 ? 131.475 107.299 151.333 1.00 71.84  ? 155 MET   R C   1 
ATOM   7158 O O   . MET   E 5 305 ? 130.665 106.726 152.068 1.00 71.84  ? 155 MET   R O   1 
ATOM   7159 C CB  . MET   E 5 305 ? 131.939 106.213 149.132 1.00 71.84  ? 155 MET   R CB  1 
ATOM   7160 C CG  . MET   E 5 305 ? 131.587 106.072 147.662 1.00 71.84  ? 155 MET   R CG  1 
ATOM   7161 S SD  . MET   E 5 305 ? 129.832 105.738 147.398 1.00 71.84  ? 155 MET   R SD  1 
ATOM   7162 C CE  . MET   E 5 305 ? 129.238 107.350 146.890 1.00 71.84  ? 155 MET   R CE  1 
ATOM   7163 N N   . LEU   E 5 306 ? 132.569 107.885 151.803 1.00 71.27  ? 156 LEU   R N   1 
ATOM   7164 C CA  . LEU   E 5 306 ? 132.718 108.127 153.230 1.00 71.27  ? 156 LEU   R CA  1 
ATOM   7165 C C   . LEU   E 5 306 ? 131.609 109.077 153.660 1.00 71.27  ? 156 LEU   R C   1 
ATOM   7166 O O   . LEU   E 5 306 ? 131.617 110.259 153.303 1.00 71.27  ? 156 LEU   R O   1 
ATOM   7167 C CB  . LEU   E 5 306 ? 134.101 108.693 153.530 1.00 71.27  ? 156 LEU   R CB  1 
ATOM   7168 C CG  . LEU   E 5 306 ? 135.154 107.605 153.758 1.00 71.27  ? 156 LEU   R CG  1 
ATOM   7169 C CD1 . LEU   E 5 306 ? 136.551 108.190 153.789 1.00 71.27  ? 156 LEU   R CD1 1 
ATOM   7170 C CD2 . LEU   E 5 306 ? 134.861 106.846 155.043 1.00 71.27  ? 156 LEU   R CD2 1 
ATOM   7171 N N   . GLU   E 5 307 ? 130.659 108.562 154.427 1.00 67.77  ? 157 GLU   R N   1 
ATOM   7172 C CA  . GLU   E 5 307 ? 129.360 109.191 154.577 1.00 67.77  ? 157 GLU   R CA  1 
ATOM   7173 C C   . GLU   E 5 307 ? 128.850 108.887 155.976 1.00 67.77  ? 157 GLU   R C   1 
ATOM   7174 O O   . GLU   E 5 307 ? 129.630 108.576 156.881 1.00 67.77  ? 157 GLU   R O   1 
ATOM   7175 C CB  . GLU   E 5 307 ? 128.404 108.711 153.476 1.00 67.77  ? 157 GLU   R CB  1 
ATOM   7176 N N   . TRP   E 5 308 ? 127.533 108.963 156.152 1.00 71.08  ? 158 TRP   R N   1 
ATOM   7177 C CA  . TRP   E 5 308 ? 126.919 108.773 157.459 1.00 71.08  ? 158 TRP   R CA  1 
ATOM   7178 C C   . TRP   E 5 308 ? 127.105 107.318 157.866 1.00 71.08  ? 158 TRP   R C   1 
ATOM   7179 O O   . TRP   E 5 308 ? 126.139 106.555 157.948 1.00 71.08  ? 158 TRP   R O   1 
ATOM   7180 C CB  . TRP   E 5 308 ? 125.425 109.119 157.413 1.00 71.08  ? 158 TRP   R CB  1 
ATOM   7181 C CG  . TRP   E 5 308 ? 125.100 110.405 156.712 1.00 71.08  ? 158 TRP   R CG  1 
ATOM   7182 C CD1 . TRP   E 5 308 ? 125.170 110.646 155.376 1.00 71.08  ? 158 TRP   R CD1 1 
ATOM   7183 C CD2 . TRP   E 5 308 ? 124.612 111.606 157.307 1.00 71.08  ? 158 TRP   R CD2 1 
ATOM   7184 N NE1 . TRP   E 5 308 ? 124.787 111.927 155.101 1.00 71.08  ? 158 TRP   R NE1 1 
ATOM   7185 C CE2 . TRP   E 5 308 ? 124.433 112.540 156.271 1.00 71.08  ? 158 TRP   R CE2 1 
ATOM   7186 C CE3 . TRP   E 5 308 ? 124.317 111.988 158.619 1.00 71.08  ? 158 TRP   R CE3 1 
ATOM   7187 C CZ2 . TRP   E 5 308 ? 123.970 113.834 156.504 1.00 71.08  ? 158 TRP   R CZ2 1 
ATOM   7188 C CZ3 . TRP   E 5 308 ? 123.859 113.273 158.849 1.00 71.08  ? 158 TRP   R CZ3 1 
ATOM   7189 C CH2 . TRP   E 5 308 ? 123.690 114.180 157.797 1.00 71.08  ? 158 TRP   R CH2 1 
ATOM   7190 N N   . ARG   E 5 309 ? 128.354 106.936 158.112 1.00 75.43  ? 159 ARG   R N   1 
ATOM   7191 C CA  . ARG   E 5 309 ? 128.721 105.557 158.402 1.00 75.43  ? 159 ARG   R CA  1 
ATOM   7192 C C   . ARG   E 5 309 ? 128.236 104.622 157.299 1.00 75.43  ? 159 ARG   R C   1 
ATOM   7193 O O   . ARG   E 5 309 ? 127.716 103.533 157.549 1.00 75.43  ? 159 ARG   R O   1 
ATOM   7194 C CB  . ARG   E 5 309 ? 128.194 105.125 159.770 1.00 75.43  ? 159 ARG   R CB  1 
ATOM   7195 C CG  . ARG   E 5 309 ? 129.269 105.037 160.830 1.00 75.43  ? 159 ARG   R CG  1 
ATOM   7196 C CD  . ARG   E 5 309 ? 129.982 106.365 160.984 1.00 75.43  ? 159 ARG   R CD  1 
ATOM   7197 N NE  . ARG   E 5 309 ? 131.056 106.298 161.970 1.00 75.43  ? 159 ARG   R NE  1 
ATOM   7198 C CZ  . ARG   E 5 309 ? 131.848 107.319 162.283 1.00 75.43  ? 159 ARG   R CZ  1 
ATOM   7199 N NH1 . ARG   E 5 309 ? 132.801 107.168 163.192 1.00 75.43  ? 159 ARG   R NH1 1 
ATOM   7200 N NH2 . ARG   E 5 309 ? 131.688 108.492 161.685 1.00 75.43  ? 159 ARG   R NH2 1 
ATOM   7201 N N   . PHE   E 5 310 ? 128.412 105.062 156.058 1.00 73.38  ? 160 PHE   R N   1 
ATOM   7202 C CA  . PHE   E 5 310 ? 128.065 104.234 154.913 1.00 73.38  ? 160 PHE   R CA  1 
ATOM   7203 C C   . PHE   E 5 310 ? 129.295 103.947 154.060 1.00 73.38  ? 160 PHE   R C   1 
ATOM   7204 O O   . PHE   E 5 310 ? 130.349 103.589 154.579 1.00 73.38  ? 160 PHE   R O   1 
ATOM   7205 C CB  . PHE   E 5 310 ? 126.984 104.905 154.070 1.00 73.38  ? 160 PHE   R CB  1 
ATOM   7206 C CG  . PHE   E 5 310 ? 126.058 103.938 153.393 1.00 73.38  ? 160 PHE   R CG  1 
ATOM   7207 C CD1 . PHE   E 5 310 ? 125.304 103.046 154.134 1.00 73.38  ? 160 PHE   R CD1 1 
ATOM   7208 C CD2 . PHE   E 5 310 ? 125.952 103.913 152.014 1.00 73.38  ? 160 PHE   R CD2 1 
ATOM   7209 C CE1 . PHE   E 5 310 ? 124.453 102.153 153.512 1.00 73.38  ? 160 PHE   R CE1 1 
ATOM   7210 C CE2 . PHE   E 5 310 ? 125.103 103.024 151.384 1.00 73.38  ? 160 PHE   R CE2 1 
ATOM   7211 C CZ  . PHE   E 5 310 ? 124.352 102.141 152.135 1.00 73.38  ? 160 PHE   R CZ  1 
ATOM   7212 N N   . THR   E 5 325 ? 137.312 104.208 161.040 1.00 82.30  ? 175 THR   R N   1 
ATOM   7213 C CA  . THR   E 5 325 ? 137.015 105.484 161.674 1.00 82.30  ? 175 THR   R CA  1 
ATOM   7214 C C   . THR   E 5 325 ? 137.691 106.623 160.931 1.00 82.30  ? 175 THR   R C   1 
ATOM   7215 O O   . THR   E 5 325 ? 138.239 107.538 161.542 1.00 82.30  ? 175 THR   R O   1 
ATOM   7216 C CB  . THR   E 5 325 ? 137.465 105.507 163.143 1.00 82.30  ? 175 THR   R CB  1 
ATOM   7217 N N   . SER   E 5 326 ? 137.642 106.563 159.599 1.00 83.92  ? 176 SER   R N   1 
ATOM   7218 C CA  . SER   E 5 326 ? 138.282 107.551 158.739 1.00 83.92  ? 176 SER   R CA  1 
ATOM   7219 C C   . SER   E 5 326 ? 137.371 108.725 158.418 1.00 83.92  ? 176 SER   R C   1 
ATOM   7220 O O   . SER   E 5 326 ? 137.544 109.375 157.379 1.00 83.92  ? 176 SER   R O   1 
ATOM   7221 C CB  . SER   E 5 326 ? 138.766 106.887 157.450 1.00 83.92  ? 176 SER   R CB  1 
ATOM   7222 N N   . ASP   E 5 327 ? 136.414 109.022 159.280 1.00 84.07  ? 177 ASP   R N   1 
ATOM   7223 C CA  . ASP   E 5 327 ? 135.476 110.098 158.995 1.00 84.07  ? 177 ASP   R CA  1 
ATOM   7224 C C   . ASP   E 5 327 ? 136.098 111.475 159.110 1.00 84.07  ? 177 ASP   R C   1 
ATOM   7225 O O   . ASP   E 5 327 ? 135.361 112.467 159.041 1.00 84.07  ? 177 ASP   R O   1 
ATOM   7226 C CB  . ASP   E 5 327 ? 134.268 109.995 159.928 1.00 84.07  ? 177 ASP   R CB  1 
ATOM   7227 N N   . PHE   E 5 328 ? 137.413 111.591 159.280 1.00 84.24  ? 178 PHE   R N   1 
ATOM   7228 C CA  . PHE   E 5 328 ? 138.042 112.893 159.426 1.00 84.24  ? 178 PHE   R CA  1 
ATOM   7229 C C   . PHE   E 5 328 ? 138.448 113.520 158.101 1.00 84.24  ? 178 PHE   R C   1 
ATOM   7230 O O   . PHE   E 5 328 ? 138.732 114.722 158.068 1.00 84.24  ? 178 PHE   R O   1 
ATOM   7231 C CB  . PHE   E 5 328 ? 139.280 112.793 160.322 1.00 84.24  ? 178 PHE   R CB  1 
ATOM   7232 C CG  . PHE   E 5 328 ? 138.967 112.656 161.783 1.00 84.24  ? 178 PHE   R CG  1 
ATOM   7233 C CD1 . PHE   E 5 328 ? 139.504 113.543 162.701 1.00 84.24  ? 178 PHE   R CD1 1 
ATOM   7234 C CD2 . PHE   E 5 328 ? 138.152 111.637 162.244 1.00 84.24  ? 178 PHE   R CD2 1 
ATOM   7235 C CE1 . PHE   E 5 328 ? 139.226 113.423 164.049 1.00 84.24  ? 178 PHE   R CE1 1 
ATOM   7236 C CE2 . PHE   E 5 328 ? 137.871 111.510 163.591 1.00 84.24  ? 178 PHE   R CE2 1 
ATOM   7237 C CZ  . PHE   E 5 328 ? 138.408 112.405 164.495 1.00 84.24  ? 178 PHE   R CZ  1 
ATOM   7238 N N   . ILE   E 5 329 ? 138.491 112.752 157.018 1.00 80.45  ? 179 ILE   R N   1 
ATOM   7239 C CA  . ILE   E 5 329 ? 138.915 113.302 155.731 1.00 80.45  ? 179 ILE   R CA  1 
ATOM   7240 C C   . ILE   E 5 329 ? 137.817 114.132 155.062 1.00 80.45  ? 179 ILE   R C   1 
ATOM   7241 O O   . ILE   E 5 329 ? 138.147 115.156 154.438 1.00 80.45  ? 179 ILE   R O   1 
ATOM   7242 C CB  . ILE   E 5 329 ? 139.459 112.198 154.802 1.00 80.45  ? 179 ILE   R CB  1 
ATOM   7243 C CG1 . ILE   E 5 329 ? 139.933 112.790 153.470 1.00 80.45  ? 179 ILE   R CG1 1 
ATOM   7244 C CG2 . ILE   E 5 329 ? 138.474 111.072 154.593 1.00 80.45  ? 179 ILE   R CG2 1 
ATOM   7245 C CD1 . ILE   E 5 329 ? 141.133 113.703 153.600 1.00 80.45  ? 179 ILE   R CD1 1 
ATOM   7246 N N   . PRO   E 5 330 ? 136.524 113.783 155.146 1.00 78.17  ? 180 PRO   R N   1 
ATOM   7247 C CA  . PRO   E 5 330 ? 135.524 114.701 154.582 1.00 78.17  ? 180 PRO   R CA  1 
ATOM   7248 C C   . PRO   E 5 330 ? 135.545 116.062 155.241 1.00 78.17  ? 180 PRO   R C   1 
ATOM   7249 O O   . PRO   E 5 330 ? 135.284 117.073 154.574 1.00 78.17  ? 180 PRO   R O   1 
ATOM   7250 C CB  . PRO   E 5 330 ? 134.195 113.976 154.828 1.00 78.17  ? 180 PRO   R CB  1 
ATOM   7251 C CG  . PRO   E 5 330 ? 134.565 112.570 155.053 1.00 78.17  ? 180 PRO   R CG  1 
ATOM   7252 C CD  . PRO   E 5 330 ? 135.850 112.641 155.786 1.00 78.17  ? 180 PRO   R CD  1 
ATOM   7253 N N   . VAL   E 5 331 ? 135.850 116.115 156.538 1.00 77.35  ? 181 VAL   R N   1 
ATOM   7254 C CA  . VAL   E 5 331 ? 135.936 117.397 157.226 1.00 77.35  ? 181 VAL   R CA  1 
ATOM   7255 C C   . VAL   E 5 331 ? 137.036 118.243 156.607 1.00 77.35  ? 181 VAL   R C   1 
ATOM   7256 O O   . VAL   E 5 331 ? 136.853 119.435 156.336 1.00 77.35  ? 181 VAL   R O   1 
ATOM   7257 C CB  . VAL   E 5 331 ? 136.166 117.187 158.733 1.00 77.35  ? 181 VAL   R CB  1 
ATOM   7258 C CG1 . VAL   E 5 331 ? 136.182 118.524 159.459 1.00 77.35  ? 181 VAL   R CG1 1 
ATOM   7259 C CG2 . VAL   E 5 331 ? 135.100 116.271 159.310 1.00 77.35  ? 181 VAL   R CG2 1 
ATOM   7260 N N   . ALA   E 5 332 ? 138.193 117.630 156.363 1.00 77.91  ? 182 ALA   R N   1 
ATOM   7261 C CA  . ALA   E 5 332 ? 139.289 118.358 155.740 1.00 77.91  ? 182 ALA   R CA  1 
ATOM   7262 C C   . ALA   E 5 332 ? 138.895 118.847 154.356 1.00 77.91  ? 182 ALA   R C   1 
ATOM   7263 O O   . ALA   E 5 332 ? 139.155 120.002 154.003 1.00 77.91  ? 182 ALA   R O   1 
ATOM   7264 C CB  . ALA   E 5 332 ? 140.535 117.475 155.667 1.00 77.91  ? 182 ALA   R CB  1 
ATOM   7265 N N   . TRP   E 5 333 ? 138.247 117.990 153.568 1.00 72.44  ? 183 TRP   R N   1 
ATOM   7266 C CA  . TRP   E 5 333 ? 137.865 118.386 152.217 1.00 72.44  ? 183 TRP   R CA  1 
ATOM   7267 C C   . TRP   E 5 333 ? 136.927 119.586 152.240 1.00 72.44  ? 183 TRP   R C   1 
ATOM   7268 O O   . TRP   E 5 333 ? 137.166 120.595 151.562 1.00 72.44  ? 183 TRP   R O   1 
ATOM   7269 C CB  . TRP   E 5 333 ? 137.218 117.203 151.500 1.00 72.44  ? 183 TRP   R CB  1 
ATOM   7270 C CG  . TRP   E 5 333 ? 136.538 117.573 150.223 1.00 72.44  ? 183 TRP   R CG  1 
ATOM   7271 C CD1 . TRP   E 5 333 ? 135.199 117.736 150.026 1.00 72.44  ? 183 TRP   R CD1 1 
ATOM   7272 C CD2 . TRP   E 5 333 ? 137.162 117.822 148.960 1.00 72.44  ? 183 TRP   R CD2 1 
ATOM   7273 N NE1 . TRP   E 5 333 ? 134.952 118.073 148.721 1.00 72.44  ? 183 TRP   R NE1 1 
ATOM   7274 C CE2 . TRP   E 5 333 ? 136.141 118.133 148.046 1.00 72.44  ? 183 TRP   R CE2 1 
ATOM   7275 C CE3 . TRP   E 5 333 ? 138.484 117.818 148.517 1.00 72.44  ? 183 TRP   R CE3 1 
ATOM   7276 C CZ2 . TRP   E 5 333 ? 136.400 118.436 146.720 1.00 72.44  ? 183 TRP   R CZ2 1 
ATOM   7277 C CZ3 . TRP   E 5 333 ? 138.739 118.118 147.199 1.00 72.44  ? 183 TRP   R CZ3 1 
ATOM   7278 C CH2 . TRP   E 5 333 ? 137.703 118.426 146.316 1.00 72.44  ? 183 TRP   R CH2 1 
ATOM   7279 N N   . LEU   E 5 334 ? 135.865 119.506 153.040 1.00 70.55  ? 184 LEU   R N   1 
ATOM   7280 C CA  . LEU   E 5 334 ? 134.886 120.584 153.055 1.00 70.55  ? 184 LEU   R CA  1 
ATOM   7281 C C   . LEU   E 5 334 ? 135.463 121.869 153.636 1.00 70.55  ? 184 LEU   R C   1 
ATOM   7282 O O   . LEU   E 5 334 ? 135.155 122.963 153.147 1.00 70.55  ? 184 LEU   R O   1 
ATOM   7283 C CB  . LEU   E 5 334 ? 133.641 120.163 153.824 1.00 70.55  ? 184 LEU   R CB  1 
ATOM   7284 C CG  . LEU   E 5 334 ? 132.563 119.541 152.950 1.00 70.55  ? 184 LEU   R CG  1 
ATOM   7285 C CD1 . LEU   E 5 334 ? 131.345 119.170 153.780 1.00 70.55  ? 184 LEU   R CD1 1 
ATOM   7286 C CD2 . LEU   E 5 334 ? 132.191 120.508 151.846 1.00 70.55  ? 184 LEU   R CD2 1 
ATOM   7287 N N   . ILE   E 5 335 ? 136.285 121.777 154.686 1.00 72.55  ? 185 ILE   R N   1 
ATOM   7288 C CA  . ILE   E 5 335 ? 136.840 123.003 155.248 1.00 72.55  ? 185 ILE   R CA  1 
ATOM   7289 C C   . ILE   E 5 335 ? 137.816 123.633 154.268 1.00 72.55  ? 185 ILE   R C   1 
ATOM   7290 O O   . ILE   E 5 335 ? 137.906 124.863 154.164 1.00 72.55  ? 185 ILE   R O   1 
ATOM   7291 C CB  . ILE   E 5 335 ? 137.483 122.748 156.623 1.00 72.55  ? 185 ILE   R CB  1 
ATOM   7292 C CG1 . ILE   E 5 335 ? 137.765 124.079 157.318 1.00 72.55  ? 185 ILE   R CG1 1 
ATOM   7293 C CG2 . ILE   E 5 335 ? 138.769 121.949 156.501 1.00 72.55  ? 185 ILE   R CG2 1 
ATOM   7294 C CD1 . ILE   E 5 335 ? 136.518 124.853 157.679 1.00 72.55  ? 185 ILE   R CD1 1 
ATOM   7295 N N   . PHE   E 5 336 ? 138.551 122.807 153.521 1.00 72.53  ? 186 PHE   R N   1 
ATOM   7296 C CA  . PHE   E 5 336 ? 139.417 123.335 152.477 1.00 72.53  ? 186 PHE   R CA  1 
ATOM   7297 C C   . PHE   E 5 336 ? 138.603 124.079 151.435 1.00 72.53  ? 186 PHE   R C   1 
ATOM   7298 O O   . PHE   E 5 336 ? 139.002 125.152 150.980 1.00 72.53  ? 186 PHE   R O   1 
ATOM   7299 C CB  . PHE   E 5 336 ? 140.209 122.189 151.849 1.00 72.53  ? 186 PHE   R CB  1 
ATOM   7300 C CG  . PHE   E 5 336 ? 140.816 122.516 150.522 1.00 72.53  ? 186 PHE   R CG  1 
ATOM   7301 C CD1 . PHE   E 5 336 ? 141.708 123.564 150.388 1.00 72.53  ? 186 PHE   R CD1 1 
ATOM   7302 C CD2 . PHE   E 5 336 ? 140.516 121.750 149.408 1.00 72.53  ? 186 PHE   R CD2 1 
ATOM   7303 C CE1 . PHE   E 5 336 ? 142.277 123.855 149.163 1.00 72.53  ? 186 PHE   R CE1 1 
ATOM   7304 C CE2 . PHE   E 5 336 ? 141.079 122.034 148.182 1.00 72.53  ? 186 PHE   R CE2 1 
ATOM   7305 C CZ  . PHE   E 5 336 ? 141.961 123.089 148.058 1.00 72.53  ? 186 PHE   R CZ  1 
ATOM   7306 N N   . LEU   E 5 337 ? 137.445 123.533 151.060 1.00 69.34  ? 187 LEU   R N   1 
ATOM   7307 C CA  . LEU   E 5 337 ? 136.609 124.211 150.073 1.00 69.34  ? 187 LEU   R CA  1 
ATOM   7308 C C   . LEU   E 5 337 ? 136.054 125.520 150.623 1.00 69.34  ? 187 LEU   R C   1 
ATOM   7309 O O   . LEU   E 5 337 ? 135.944 126.517 149.893 1.00 69.34  ? 187 LEU   R O   1 
ATOM   7310 C CB  . LEU   E 5 337 ? 135.486 123.289 149.611 1.00 69.34  ? 187 LEU   R CB  1 
ATOM   7311 C CG  . LEU   E 5 337 ? 135.809 122.447 148.375 1.00 69.34  ? 187 LEU   R CG  1 
ATOM   7312 C CD1 . LEU   E 5 337 ? 135.925 123.317 147.153 1.00 69.34  ? 187 LEU   R CD1 1 
ATOM   7313 C CD2 . LEU   E 5 337 ? 137.086 121.658 148.557 1.00 69.34  ? 187 LEU   R CD2 1 
ATOM   7314 N N   . CYS   E 5 338 ? 135.713 125.542 151.914 1.00 71.77  ? 188 CYS   R N   1 
ATOM   7315 C CA  . CYS   E 5 338 ? 135.268 126.784 152.542 1.00 71.77  ? 188 CYS   R CA  1 
ATOM   7316 C C   . CYS   E 5 338 ? 136.369 127.837 152.522 1.00 71.77  ? 188 CYS   R C   1 
ATOM   7317 O O   . CYS   E 5 338 ? 136.116 129.012 152.229 1.00 71.77  ? 188 CYS   R O   1 
ATOM   7318 C CB  . CYS   E 5 338 ? 134.815 126.513 153.976 1.00 71.77  ? 188 CYS   R CB  1 
ATOM   7319 S SG  . CYS   E 5 338 ? 134.431 128.000 154.926 1.00 71.77  ? 188 CYS   R SG  1 
ATOM   7320 N N   . VAL   E 5 339 ? 137.601 127.431 152.823 1.00 68.31  ? 189 VAL   R N   1 
ATOM   7321 C CA  . VAL   E 5 339 ? 138.723 128.362 152.762 1.00 68.31  ? 189 VAL   R CA  1 
ATOM   7322 C C   . VAL   E 5 339 ? 138.952 128.820 151.329 1.00 68.31  ? 189 VAL   R C   1 
ATOM   7323 O O   . VAL   E 5 339 ? 139.335 129.969 151.084 1.00 68.31  ? 189 VAL   R O   1 
ATOM   7324 C CB  . VAL   E 5 339 ? 139.985 127.715 153.365 1.00 68.31  ? 189 VAL   R CB  1 
ATOM   7325 C CG1 . VAL   E 5 339 ? 141.202 128.605 153.161 1.00 68.31  ? 189 VAL   R CG1 1 
ATOM   7326 C CG2 . VAL   E 5 339 ? 139.776 127.428 154.845 1.00 68.31  ? 189 VAL   R CG2 1 
ATOM   7327 N N   . VAL   E 5 340 ? 138.732 127.929 150.362 1.00 62.18  ? 190 VAL   R N   1 
ATOM   7328 C CA  . VAL   E 5 340 ? 138.887 128.303 148.960 1.00 62.18  ? 190 VAL   R CA  1 
ATOM   7329 C C   . VAL   E 5 340 ? 137.921 129.416 148.610 1.00 62.18  ? 190 VAL   R C   1 
ATOM   7330 O O   . VAL   E 5 340 ? 138.295 130.422 147.992 1.00 62.18  ? 190 VAL   R O   1 
ATOM   7331 C CB  . VAL   E 5 340 ? 138.678 127.085 148.048 1.00 62.18  ? 190 VAL   R CB  1 
ATOM   7332 C CG1 . VAL   E 5 340 ? 138.509 127.529 146.632 1.00 62.18  ? 190 VAL   R CG1 1 
ATOM   7333 C CG2 . VAL   E 5 340 ? 139.864 126.152 148.146 1.00 62.18  ? 190 VAL   R CG2 1 
ATOM   7334 N N   . LEU   E 5 341 ? 136.663 129.257 149.004 1.00 63.01  ? 191 LEU   R N   1 
ATOM   7335 C CA  . LEU   E 5 341 ? 135.690 130.294 148.697 1.00 63.01  ? 191 LEU   R CA  1 
ATOM   7336 C C   . LEU   E 5 341 ? 136.020 131.578 149.442 1.00 63.01  ? 191 LEU   R C   1 
ATOM   7337 O O   . LEU   E 5 341 ? 135.882 132.675 148.887 1.00 63.01  ? 191 LEU   R O   1 
ATOM   7338 C CB  . LEU   E 5 341 ? 134.277 129.812 149.017 1.00 63.01  ? 191 LEU   R CB  1 
ATOM   7339 C CG  . LEU   E 5 341 ? 133.153 130.658 148.420 1.00 63.01  ? 191 LEU   R CG  1 
ATOM   7340 C CD1 . LEU   E 5 341 ? 131.998 129.774 147.992 1.00 63.01  ? 191 LEU   R CD1 1 
ATOM   7341 C CD2 . LEU   E 5 341 ? 132.676 131.702 149.406 1.00 63.01  ? 191 LEU   R CD2 1 
ATOM   7342 N N   . CYS   E 5 342 ? 136.494 131.461 150.683 1.00 65.86  ? 192 CYS   R N   1 
ATOM   7343 C CA  . CYS   E 5 342 ? 136.854 132.645 151.458 1.00 65.86  ? 192 CYS   R CA  1 
ATOM   7344 C C   . CYS   E 5 342 ? 137.976 133.431 150.789 1.00 65.86  ? 192 CYS   R C   1 
ATOM   7345 O O   . CYS   E 5 342 ? 137.883 134.653 150.633 1.00 65.86  ? 192 CYS   R O   1 
ATOM   7346 C CB  . CYS   E 5 342 ? 137.255 132.238 152.876 1.00 65.86  ? 192 CYS   R CB  1 
ATOM   7347 S SG  . CYS   E 5 342 ? 138.026 133.557 153.843 1.00 65.86  ? 192 CYS   R SG  1 
ATOM   7348 N N   . VAL   E 5 343 ? 139.042 132.744 150.374 1.00 61.89  ? 193 VAL   R N   1 
ATOM   7349 C CA  . VAL   E 5 343 ? 140.179 133.435 149.775 1.00 61.89  ? 193 VAL   R CA  1 
ATOM   7350 C C   . VAL   E 5 343 ? 139.825 133.978 148.396 1.00 61.89  ? 193 VAL   R C   1 
ATOM   7351 O O   . VAL   E 5 343 ? 140.259 135.075 148.027 1.00 61.89  ? 193 VAL   R O   1 
ATOM   7352 C CB  . VAL   E 5 343 ? 141.418 132.523 149.730 1.00 61.89  ? 193 VAL   R CB  1 
ATOM   7353 C CG1 . VAL   E 5 343 ? 141.790 132.070 151.133 1.00 61.89  ? 193 VAL   R CG1 1 
ATOM   7354 C CG2 . VAL   E 5 343 ? 141.196 131.332 148.825 1.00 61.89  ? 193 VAL   R CG2 1 
ATOM   7355 N N   . SER   E 5 344 ? 139.040 133.235 147.610 1.00 60.00  ? 194 SER   R N   1 
ATOM   7356 C CA  . SER   E 5 344 ? 138.617 133.749 146.311 1.00 60.00  ? 194 SER   R CA  1 
ATOM   7357 C C   . SER   E 5 344 ? 137.797 135.021 146.470 1.00 60.00  ? 194 SER   R C   1 
ATOM   7358 O O   . SER   E 5 344 ? 138.048 136.032 145.793 1.00 60.00  ? 194 SER   R O   1 
ATOM   7359 C CB  . SER   E 5 344 ? 137.825 132.682 145.560 1.00 60.00  ? 194 SER   R CB  1 
ATOM   7360 O OG  . SER   E 5 344 ? 138.636 131.557 145.268 1.00 60.00  ? 194 SER   R OG  1 
ATOM   7361 N N   . SER   E 5 345 ? 136.840 135.004 147.397 1.00 63.61  ? 195 SER   R N   1 
ATOM   7362 C CA  . SER   E 5 345 ? 136.063 136.196 147.703 1.00 63.61  ? 195 SER   R CA  1 
ATOM   7363 C C   . SER   E 5 345 ? 136.960 137.349 148.121 1.00 63.61  ? 195 SER   R C   1 
ATOM   7364 O O   . SER   E 5 345 ? 136.840 138.467 147.602 1.00 63.61  ? 195 SER   R O   1 
ATOM   7365 C CB  . SER   E 5 345 ? 135.058 135.878 148.807 1.00 63.61  ? 195 SER   R CB  1 
ATOM   7366 O OG  . SER   E 5 345 ? 134.453 137.054 149.310 1.00 63.61  ? 195 SER   R OG  1 
ATOM   7367 N N   . LEU   E 5 346 ? 137.863 137.098 149.069 1.00 64.93  ? 196 LEU   R N   1 
ATOM   7368 C CA  . LEU   E 5 346 ? 138.682 138.176 149.608 1.00 64.93  ? 196 LEU   R CA  1 
ATOM   7369 C C   . LEU   E 5 346 ? 139.573 138.782 148.536 1.00 64.93  ? 196 LEU   R C   1 
ATOM   7370 O O   . LEU   E 5 346 ? 139.732 140.003 148.477 1.00 64.93  ? 196 LEU   R O   1 
ATOM   7371 C CB  . LEU   E 5 346 ? 139.518 137.668 150.780 1.00 64.93  ? 196 LEU   R CB  1 
ATOM   7372 C CG  . LEU   E 5 346 ? 139.764 138.670 151.908 1.00 64.93  ? 196 LEU   R CG  1 
ATOM   7373 C CD1 . LEU   E 5 346 ? 138.455 139.293 152.367 1.00 64.93  ? 196 LEU   R CD1 1 
ATOM   7374 C CD2 . LEU   E 5 346 ? 140.483 138.005 153.072 1.00 64.93  ? 196 LEU   R CD2 1 
ATOM   7375 N N   . VAL   E 5 347 ? 140.167 137.951 147.682 1.00 59.96  ? 197 VAL   R N   1 
ATOM   7376 C CA  . VAL   E 5 347 ? 141.066 138.474 146.664 1.00 59.96  ? 197 VAL   R CA  1 
ATOM   7377 C C   . VAL   E 5 347 ? 140.295 139.289 145.639 1.00 59.96  ? 197 VAL   R C   1 
ATOM   7378 O O   . VAL   E 5 347 ? 140.738 140.373 145.224 1.00 59.96  ? 197 VAL   R O   1 
ATOM   7379 C CB  . VAL   E 5 347 ? 141.855 137.330 146.012 1.00 59.96  ? 197 VAL   R CB  1 
ATOM   7380 C CG1 . VAL   E 5 347 ? 142.536 137.811 144.758 1.00 59.96  ? 197 VAL   R CG1 1 
ATOM   7381 C CG2 . VAL   E 5 347 ? 142.875 136.794 146.984 1.00 59.96  ? 197 VAL   R CG2 1 
ATOM   7382 N N   . LEU   E 5 348 ? 139.128 138.798 145.213 1.00 61.40  ? 198 LEU   R N   1 
ATOM   7383 C CA  . LEU   E 5 348 ? 138.336 139.575 144.269 1.00 61.40  ? 198 LEU   R CA  1 
ATOM   7384 C C   . LEU   E 5 348 ? 137.857 140.875 144.888 1.00 61.40  ? 198 LEU   R C   1 
ATOM   7385 O O   . LEU   E 5 348 ? 137.628 141.855 144.174 1.00 61.40  ? 198 LEU   R O   1 
ATOM   7386 C CB  . LEU   E 5 348 ? 137.148 138.760 143.767 1.00 61.40  ? 198 LEU   R CB  1 
ATOM   7387 C CG  . LEU   E 5 348 ? 136.399 139.333 142.564 1.00 61.40  ? 198 LEU   R CG  1 
ATOM   7388 C CD1 . LEU   E 5 348 ? 135.967 138.212 141.638 1.00 61.40  ? 198 LEU   R CD1 1 
ATOM   7389 C CD2 . LEU   E 5 348 ? 135.201 140.142 143.004 1.00 61.40  ? 198 LEU   R CD2 1 
ATOM   7390 N N   . LEU   E 5 349 ? 137.691 140.907 146.208 1.00 67.33  ? 199 LEU   R N   1 
ATOM   7391 C CA  . LEU   E 5 349 ? 137.310 142.157 146.852 1.00 67.33  ? 199 LEU   R CA  1 
ATOM   7392 C C   . LEU   E 5 349 ? 138.489 143.116 146.920 1.00 67.33  ? 199 LEU   R C   1 
ATOM   7393 O O   . LEU   E 5 349 ? 138.350 144.305 146.610 1.00 67.33  ? 199 LEU   R O   1 
ATOM   7394 C CB  . LEU   E 5 349 ? 136.760 141.881 148.250 1.00 67.33  ? 199 LEU   R CB  1 
ATOM   7395 C CG  . LEU   E 5 349 ? 135.771 142.907 148.806 1.00 67.33  ? 199 LEU   R CG  1 
ATOM   7396 C CD1 . LEU   E 5 349 ? 134.411 142.743 148.146 1.00 67.33  ? 199 LEU   R CD1 1 
ATOM   7397 C CD2 . LEU   E 5 349 ? 135.657 142.782 150.317 1.00 67.33  ? 199 LEU   R CD2 1 
ATOM   7398 N N   . VAL   E 5 350 ? 139.663 142.606 147.289 1.00 67.45  ? 200 VAL   R N   1 
ATOM   7399 C CA  . VAL   E 5 350 ? 140.840 143.453 147.435 1.00 67.45  ? 200 VAL   R CA  1 
ATOM   7400 C C   . VAL   E 5 350 ? 141.206 144.104 146.111 1.00 67.45  ? 200 VAL   R C   1 
ATOM   7401 O O   . VAL   E 5 350 ? 141.517 145.299 146.059 1.00 67.45  ? 200 VAL   R O   1 
ATOM   7402 C CB  . VAL   E 5 350 ? 142.018 142.644 148.006 1.00 67.45  ? 200 VAL   R CB  1 
ATOM   7403 C CG1 . VAL   E 5 350 ? 143.268 143.500 148.050 1.00 67.45  ? 200 VAL   R CG1 1 
ATOM   7404 C CG2 . VAL   E 5 350 ? 141.693 142.162 149.400 1.00 67.45  ? 200 VAL   R CG2 1 
ATOM   7405 N N   . ARG   E 5 351 ? 141.177 143.338 145.019 1.00 67.09  ? 201 ARG   R N   1 
ATOM   7406 C CA  . ARG   E 5 351 ? 141.680 143.882 143.762 1.00 67.09  ? 201 ARG   R CA  1 
ATOM   7407 C C   . ARG   E 5 351 ? 140.863 145.083 143.302 1.00 67.09  ? 201 ARG   R C   1 
ATOM   7408 O O   . ARG   E 5 351 ? 141.426 146.071 142.818 1.00 67.09  ? 201 ARG   R O   1 
ATOM   7409 C CB  . ARG   E 5 351 ? 141.707 142.812 142.678 1.00 67.09  ? 201 ARG   R CB  1 
ATOM   7410 C CG  . ARG   E 5 351 ? 142.793 143.064 141.658 1.00 67.09  ? 201 ARG   R CG  1 
ATOM   7411 C CD  . ARG   E 5 351 ? 142.524 142.338 140.359 1.00 67.09  ? 201 ARG   R CD  1 
ATOM   7412 N NE  . ARG   E 5 351 ? 143.699 142.323 139.491 1.00 67.09  ? 201 ARG   R NE  1 
ATOM   7413 C CZ  . ARG   E 5 351 ? 144.069 143.340 138.719 1.00 67.09  ? 201 ARG   R CZ  1 
ATOM   7414 N NH1 . ARG   E 5 351 ? 145.152 143.238 137.961 1.00 67.09  ? 201 ARG   R NH1 1 
ATOM   7415 N NH2 . ARG   E 5 351 ? 143.357 144.458 138.704 1.00 67.09  ? 201 ARG   R NH2 1 
ATOM   7416 N N   . ILE   E 5 352 ? 139.537 145.023 143.440 1.00 71.62  ? 202 ILE   R N   1 
ATOM   7417 C CA  . ILE   E 5 352 ? 138.710 146.168 143.064 1.00 71.62  ? 202 ILE   R CA  1 
ATOM   7418 C C   . ILE   E 5 352 ? 138.639 147.223 144.156 1.00 71.62  ? 202 ILE   R C   1 
ATOM   7419 O O   . ILE   E 5 352 ? 138.259 148.367 143.872 1.00 71.62  ? 202 ILE   R O   1 
ATOM   7420 C CB  . ILE   E 5 352 ? 137.297 145.705 142.667 1.00 71.62  ? 202 ILE   R CB  1 
ATOM   7421 C CG1 . ILE   E 5 352 ? 137.387 144.506 141.731 1.00 71.62  ? 202 ILE   R CG1 1 
ATOM   7422 C CG2 . ILE   E 5 352 ? 136.539 146.808 141.960 1.00 71.62  ? 202 ILE   R CG2 1 
ATOM   7423 C CD1 . ILE   E 5 352 ? 138.037 144.829 140.410 1.00 71.62  ? 202 ILE   R CD1 1 
ATOM   7424 N N   . LEU   E 5 353 ? 139.008 146.890 145.397 1.00 75.06  ? 203 LEU   R N   1 
ATOM   7425 C CA  . LEU   E 5 353 ? 139.156 147.932 146.409 1.00 75.06  ? 203 LEU   R CA  1 
ATOM   7426 C C   . LEU   E 5 353 ? 140.192 148.960 145.981 1.00 75.06  ? 203 LEU   R C   1 
ATOM   7427 O O   . LEU   E 5 353 ? 139.923 150.167 145.977 1.00 75.06  ? 203 LEU   R O   1 
ATOM   7428 C CB  . LEU   E 5 353 ? 139.541 147.324 147.759 1.00 75.06  ? 203 LEU   R CB  1 
ATOM   7429 C CG  . LEU   E 5 353 ? 138.462 146.624 148.586 1.00 75.06  ? 203 LEU   R CG  1 
ATOM   7430 C CD1 . LEU   E 5 353 ? 139.076 145.951 149.803 1.00 75.06  ? 203 LEU   R CD1 1 
ATOM   7431 C CD2 . LEU   E 5 353 ? 137.390 147.613 149.006 1.00 75.06  ? 203 LEU   R CD2 1 
ATOM   7432 N N   . CYS   E 5 354 ? 141.382 148.501 145.609 1.00 79.66  ? 204 CYS   R N   1 
ATOM   7433 C CA  . CYS   E 5 354 ? 142.461 149.397 145.200 1.00 79.66  ? 204 CYS   R CA  1 
ATOM   7434 C C   . CYS   E 5 354 ? 142.424 149.660 143.701 1.00 79.66  ? 204 CYS   R C   1 
ATOM   7435 O O   . CYS   E 5 354 ? 143.414 149.499 142.990 1.00 79.66  ? 204 CYS   R O   1 
ATOM   7436 C CB  . CYS   E 5 354 ? 143.807 148.822 145.623 1.00 79.66  ? 204 CYS   R CB  1 
ATOM   7437 S SG  . CYS   E 5 354 ? 144.129 147.139 145.068 1.00 79.66  ? 204 CYS   R SG  1 
ATOM   7438 N N   . GLY   E 5 355 ? 141.258 150.075 143.214 1.00 85.51  ? 205 GLY   R N   1 
ATOM   7439 C CA  . GLY   E 5 355 ? 141.092 150.414 141.816 1.00 85.51  ? 205 GLY   R CA  1 
ATOM   7440 C C   . GLY   E 5 355 ? 140.947 151.905 141.602 1.00 85.51  ? 205 GLY   R C   1 
ATOM   7441 O O   . GLY   E 5 355 ? 141.713 152.695 142.163 1.00 85.51  ? 205 GLY   R O   1 
ATOM   7442 N N   . SER   E 5 356 ? 139.965 152.304 140.796 1.00 92.24  ? 206 SER   R N   1 
ATOM   7443 C CA  . SER   E 5 356 ? 139.729 153.720 140.528 1.00 92.24  ? 206 SER   R CA  1 
ATOM   7444 C C   . SER   E 5 356 ? 138.326 153.879 139.970 1.00 92.24  ? 206 SER   R C   1 
ATOM   7445 O O   . SER   E 5 356 ? 137.963 153.188 139.013 1.00 92.24  ? 206 SER   R O   1 
ATOM   7446 C CB  . SER   E 5 356 ? 140.765 154.272 139.549 1.00 92.24  ? 206 SER   R CB  1 
ATOM   7447 N N   . ARG   E 5 357 ? 137.544 154.778 140.572 1.00 95.20  ? 207 ARG   R N   1 
ATOM   7448 C CA  . ARG   E 5 357 ? 136.221 155.154 140.068 1.00 95.20  ? 207 ARG   R CA  1 
ATOM   7449 C C   . ARG   E 5 357 ? 135.328 153.934 139.854 1.00 95.20  ? 207 ARG   R C   1 
ATOM   7450 O O   . ARG   E 5 357 ? 134.624 153.820 138.849 1.00 95.20  ? 207 ARG   R O   1 
ATOM   7451 C CB  . ARG   E 5 357 ? 136.342 155.970 138.780 1.00 95.20  ? 207 ARG   R CB  1 
ATOM   7452 N N   . LYS   E 5 358 ? 135.352 153.012 140.815 1.00 95.63  ? 208 LYS   R N   1 
ATOM   7453 C CA  . LYS   E 5 358 ? 134.547 151.801 140.712 1.00 95.63  ? 208 LYS   R CA  1 
ATOM   7454 C C   . LYS   E 5 358 ? 133.073 152.126 140.911 1.00 95.63  ? 208 LYS   R C   1 
ATOM   7455 O O   . LYS   E 5 358 ? 132.591 152.186 142.046 1.00 95.63  ? 208 LYS   R O   1 
ATOM   7456 C CB  . LYS   E 5 358 ? 135.009 150.760 141.733 1.00 95.63  ? 208 LYS   R CB  1 
ATOM   7457 N N   . MET   E 5 359 ? 132.358 152.351 139.810 1.00 95.48  ? 209 MET   R N   1 
ATOM   7458 C CA  . MET   E 5 359 ? 130.934 152.659 139.904 1.00 95.48  ? 209 MET   R CA  1 
ATOM   7459 C C   . MET   E 5 359 ? 130.132 151.539 140.551 1.00 95.48  ? 209 MET   R C   1 
ATOM   7460 O O   . MET   E 5 359 ? 129.248 151.842 141.371 1.00 95.48  ? 209 MET   R O   1 
ATOM   7461 C CB  . MET   E 5 359 ? 130.383 152.985 138.511 1.00 95.48  ? 209 MET   R CB  1 
ATOM   7462 N N   . PRO   E 5 360 ? 130.374 150.266 140.247 1.00 92.77  ? 210 PRO   R N   1 
ATOM   7463 C CA  . PRO   E 5 360 ? 129.546 149.199 140.824 1.00 92.77  ? 210 PRO   R CA  1 
ATOM   7464 C C   . PRO   E 5 360 ? 129.977 148.793 142.225 1.00 92.77  ? 210 PRO   R C   1 
ATOM   7465 O O   . PRO   E 5 360 ? 129.624 147.702 142.685 1.00 92.77  ? 210 PRO   R O   1 
ATOM   7466 C CB  . PRO   E 5 360 ? 129.725 148.046 139.831 1.00 92.77  ? 210 PRO   R CB  1 
ATOM   7467 N N   . LEU   E 5 361 ? 130.747 149.651 142.901 1.00 90.58  ? 211 LEU   R N   1 
ATOM   7468 C CA  . LEU   E 5 361 ? 131.236 149.322 144.236 1.00 90.58  ? 211 LEU   R CA  1 
ATOM   7469 C C   . LEU   E 5 361 ? 130.094 149.064 145.209 1.00 90.58  ? 211 LEU   R C   1 
ATOM   7470 O O   . LEU   E 5 361 ? 130.281 148.376 146.217 1.00 90.58  ? 211 LEU   R O   1 
ATOM   7471 C CB  . LEU   E 5 361 ? 132.132 150.443 144.756 1.00 90.58  ? 211 LEU   R CB  1 
ATOM   7472 C CG  . LEU   E 5 361 ? 133.259 150.024 145.702 1.00 90.58  ? 211 LEU   R CG  1 
ATOM   7473 C CD1 . LEU   E 5 361 ? 134.157 148.987 145.043 1.00 90.58  ? 211 LEU   R CD1 1 
ATOM   7474 C CD2 . LEU   E 5 361 ? 134.067 151.234 146.146 1.00 90.58  ? 211 LEU   R CD2 1 
ATOM   7475 N N   . THR   E 5 362 ? 128.911 149.609 144.933 1.00 88.98  ? 212 THR   R N   1 
ATOM   7476 C CA  . THR   E 5 362 ? 127.750 149.294 145.754 1.00 88.98  ? 212 THR   R CA  1 
ATOM   7477 C C   . THR   E 5 362 ? 127.331 147.840 145.583 1.00 88.98  ? 212 THR   R C   1 
ATOM   7478 O O   . THR   E 5 362 ? 126.964 147.174 146.557 1.00 88.98  ? 212 THR   R O   1 
ATOM   7479 C CB  . THR   E 5 362 ? 126.591 150.226 145.404 1.00 88.98  ? 212 THR   R CB  1 
ATOM   7480 O OG1 . THR   E 5 362 ? 126.224 150.035 144.031 1.00 88.98  ? 212 THR   R OG1 1 
ATOM   7481 C CG2 . THR   E 5 362 ? 126.992 151.678 145.619 1.00 88.98  ? 212 THR   R CG2 1 
ATOM   7482 N N   . ARG   E 5 363 ? 127.379 147.333 144.354 1.00 83.25  ? 213 ARG   R N   1 
ATOM   7483 C CA  . ARG   E 5 363 ? 126.859 146.010 144.040 1.00 83.25  ? 213 ARG   R CA  1 
ATOM   7484 C C   . ARG   E 5 363 ? 127.891 144.902 144.199 1.00 83.25  ? 213 ARG   R C   1 
ATOM   7485 O O   . ARG   E 5 363 ? 127.511 143.739 144.380 1.00 83.25  ? 213 ARG   R O   1 
ATOM   7486 C CB  . ARG   E 5 363 ? 126.309 146.007 142.611 1.00 83.25  ? 213 ARG   R CB  1 
ATOM   7487 C CG  . ARG   E 5 363 ? 125.465 144.800 142.257 1.00 83.25  ? 213 ARG   R CG  1 
ATOM   7488 C CD  . ARG   E 5 363 ? 124.741 145.015 140.945 1.00 83.25  ? 213 ARG   R CD  1 
ATOM   7489 N NE  . ARG   E 5 363 ? 123.966 143.845 140.545 1.00 83.25  ? 213 ARG   R NE  1 
ATOM   7490 C CZ  . ARG   E 5 363 ? 123.102 143.834 139.536 1.00 83.25  ? 213 ARG   R CZ  1 
ATOM   7491 N NH1 . ARG   E 5 363 ? 122.902 144.934 138.821 1.00 83.25  ? 213 ARG   R NH1 1 
ATOM   7492 N NH2 . ARG   E 5 363 ? 122.438 142.725 139.239 1.00 83.25  ? 213 ARG   R NH2 1 
ATOM   7493 N N   . LEU   E 5 364 ? 129.179 145.230 144.128 1.00 82.20  ? 214 LEU   R N   1 
ATOM   7494 C CA  . LEU   E 5 364 ? 130.213 144.213 144.278 1.00 82.20  ? 214 LEU   R CA  1 
ATOM   7495 C C   . LEU   E 5 364 ? 130.188 143.614 145.675 1.00 82.20  ? 214 LEU   R C   1 
ATOM   7496 O O   . LEU   E 5 364 ? 130.198 142.385 145.842 1.00 82.20  ? 214 LEU   R O   1 
ATOM   7497 C CB  . LEU   E 5 364 ? 131.580 144.817 143.979 1.00 82.20  ? 214 LEU   R CB  1 
ATOM   7498 C CG  . LEU   E 5 364 ? 132.774 143.871 144.061 1.00 82.20  ? 214 LEU   R CG  1 
ATOM   7499 C CD1 . LEU   E 5 364 ? 132.693 142.830 142.967 1.00 82.20  ? 214 LEU   R CD1 1 
ATOM   7500 C CD2 . LEU   E 5 364 ? 134.078 144.644 143.978 1.00 82.20  ? 214 LEU   R CD2 1 
ATOM   7501 N N   . TYR   E 5 365 ? 130.166 144.478 146.691 1.00 83.98  ? 215 TYR   R N   1 
ATOM   7502 C CA  . TYR   E 5 365 ? 130.030 144.012 148.063 1.00 83.98  ? 215 TYR   R CA  1 
ATOM   7503 C C   . TYR   E 5 365 ? 128.784 143.158 148.213 1.00 83.98  ? 215 TYR   R C   1 
ATOM   7504 O O   . TYR   E 5 365 ? 128.829 142.072 148.798 1.00 83.98  ? 215 TYR   R O   1 
ATOM   7505 C CB  . TYR   E 5 365 ? 129.974 145.200 149.018 1.00 83.98  ? 215 TYR   R CB  1 
ATOM   7506 C CG  . TYR   E 5 365 ? 131.155 146.128 148.928 1.00 83.98  ? 215 TYR   R CG  1 
ATOM   7507 C CD1 . TYR   E 5 365 ? 130.991 147.498 149.065 1.00 83.98  ? 215 TYR   R CD1 1 
ATOM   7508 C CD2 . TYR   E 5 365 ? 132.434 145.639 148.711 1.00 83.98  ? 215 TYR   R CD2 1 
ATOM   7509 C CE1 . TYR   E 5 365 ? 132.067 148.359 148.984 1.00 83.98  ? 215 TYR   R CE1 1 
ATOM   7510 C CE2 . TYR   E 5 365 ? 133.520 146.492 148.628 1.00 83.98  ? 215 TYR   R CE2 1 
ATOM   7511 C CZ  . TYR   E 5 365 ? 133.328 147.851 148.767 1.00 83.98  ? 215 TYR   R CZ  1 
ATOM   7512 O OH  . TYR   E 5 365 ? 134.398 148.711 148.687 1.00 83.98  ? 215 TYR   R OH  1 
ATOM   7513 N N   . VAL   E 5 366 ? 127.661 143.633 147.673 1.00 79.18  ? 216 VAL   R N   1 
ATOM   7514 C CA  . VAL   E 5 366 ? 126.407 142.890 147.762 1.00 79.18  ? 216 VAL   R CA  1 
ATOM   7515 C C   . VAL   E 5 366 ? 126.597 141.471 147.247 1.00 79.18  ? 216 VAL   R C   1 
ATOM   7516 O O   . VAL   E 5 366 ? 126.374 140.492 147.967 1.00 79.18  ? 216 VAL   R O   1 
ATOM   7517 C CB  . VAL   E 5 366 ? 125.294 143.616 146.990 1.00 79.18  ? 216 VAL   R CB  1 
ATOM   7518 C CG1 . VAL   E 5 366 ? 124.100 142.697 146.796 1.00 79.18  ? 216 VAL   R CG1 1 
ATOM   7519 C CG2 . VAL   E 5 366 ? 124.887 144.882 147.721 1.00 79.18  ? 216 VAL   R CG2 1 
ATOM   7520 N N   . THR   E 5 367 ? 127.037 141.343 145.993 1.00 77.40  ? 217 THR   R N   1 
ATOM   7521 C CA  . THR   E 5 367 ? 127.096 140.028 145.361 1.00 77.40  ? 217 THR   R CA  1 
ATOM   7522 C C   . THR   E 5 367 ? 128.057 139.102 146.093 1.00 77.40  ? 217 THR   R C   1 
ATOM   7523 O O   . THR   E 5 367 ? 127.699 137.971 146.451 1.00 77.40  ? 217 THR   R O   1 
ATOM   7524 C CB  . THR   E 5 367 ? 127.498 140.166 143.893 1.00 77.40  ? 217 THR   R CB  1 
ATOM   7525 O OG1 . THR   E 5 367 ? 126.561 141.013 143.217 1.00 77.40  ? 217 THR   R OG1 1 
ATOM   7526 C CG2 . THR   E 5 367 ? 127.509 138.802 143.221 1.00 77.40  ? 217 THR   R CG2 1 
ATOM   7527 N N   . ILE   E 5 368 ? 129.273 139.576 146.364 1.00 73.27  ? 218 ILE   R N   1 
ATOM   7528 C CA  . ILE   E 5 368 ? 130.274 138.679 146.930 1.00 73.27  ? 218 ILE   R CA  1 
ATOM   7529 C C   . ILE   E 5 368 ? 129.933 138.320 148.370 1.00 73.27  ? 218 ILE   R C   1 
ATOM   7530 O O   . ILE   E 5 368 ? 130.054 137.155 148.778 1.00 73.27  ? 218 ILE   R O   1 
ATOM   7531 C CB  . ILE   E 5 368 ? 131.675 139.293 146.811 1.00 73.27  ? 218 ILE   R CB  1 
ATOM   7532 C CG1 . ILE   E 5 368 ? 131.913 139.793 145.387 1.00 73.27  ? 218 ILE   R CG1 1 
ATOM   7533 C CG2 . ILE   E 5 368 ? 132.707 138.259 147.137 1.00 73.27  ? 218 ILE   R CG2 1 
ATOM   7534 C CD1 . ILE   E 5 368 ? 131.820 138.710 144.331 1.00 73.27  ? 218 ILE   R CD1 1 
ATOM   7535 N N   . LEU   E 5 369 ? 129.507 139.303 149.167 1.00 73.53  ? 219 LEU   R N   1 
ATOM   7536 C CA  . LEU   E 5 369 ? 129.162 139.029 150.554 1.00 73.53  ? 219 LEU   R CA  1 
ATOM   7537 C C   . LEU   E 5 369 ? 127.961 138.103 150.647 1.00 73.53  ? 219 LEU   R C   1 
ATOM   7538 O O   . LEU   E 5 369 ? 127.939 137.191 151.480 1.00 73.53  ? 219 LEU   R O   1 
ATOM   7539 C CB  . LEU   E 5 369 ? 128.893 140.336 151.294 1.00 73.53  ? 219 LEU   R CB  1 
ATOM   7540 C CG  . LEU   E 5 369 ? 129.077 140.291 152.810 1.00 73.53  ? 219 LEU   R CG  1 
ATOM   7541 C CD1 . LEU   E 5 369 ? 130.547 140.138 153.164 1.00 73.53  ? 219 LEU   R CD1 1 
ATOM   7542 C CD2 . LEU   E 5 369 ? 128.490 141.534 153.462 1.00 73.53  ? 219 LEU   R CD2 1 
ATOM   7543 N N   . LEU   E 5 370 ? 126.954 138.310 149.792 1.00 71.68  ? 220 LEU   R N   1 
ATOM   7544 C CA  . LEU   E 5 370 ? 125.812 137.408 149.778 1.00 71.68  ? 220 LEU   R CA  1 
ATOM   7545 C C   . LEU   E 5 370 ? 126.257 135.988 149.470 1.00 71.68  ? 220 LEU   R C   1 
ATOM   7546 O O   . LEU   E 5 370 ? 125.879 135.041 150.172 1.00 71.68  ? 220 LEU   R O   1 
ATOM   7547 C CB  . LEU   E 5 370 ? 124.782 137.890 148.756 1.00 71.68  ? 220 LEU   R CB  1 
ATOM   7548 C CG  . LEU   E 5 370 ? 123.375 137.289 148.818 1.00 71.68  ? 220 LEU   R CG  1 
ATOM   7549 C CD1 . LEU   E 5 370 ? 122.356 138.288 148.288 1.00 71.68  ? 220 LEU   R CD1 1 
ATOM   7550 C CD2 . LEU   E 5 370 ? 123.272 135.978 148.055 1.00 71.68  ? 220 LEU   R CD2 1 
ATOM   7551 N N   . THR   E 5 371 ? 127.077 135.823 148.432 1.00 67.77  ? 221 THR   R N   1 
ATOM   7552 C CA  . THR   E 5 371 ? 127.546 134.490 148.073 1.00 67.77  ? 221 THR   R CA  1 
ATOM   7553 C C   . THR   E 5 371 ? 128.241 133.814 149.242 1.00 67.77  ? 221 THR   R C   1 
ATOM   7554 O O   . THR   E 5 371 ? 127.893 132.687 149.619 1.00 67.77  ? 221 THR   R O   1 
ATOM   7555 C CB  . THR   E 5 371 ? 128.492 134.571 146.880 1.00 67.77  ? 221 THR   R CB  1 
ATOM   7556 O OG1 . THR   E 5 371 ? 127.783 135.044 145.727 1.00 67.77  ? 221 THR   R OG1 1 
ATOM   7557 C CG2 . THR   E 5 371 ? 129.101 133.215 146.602 1.00 67.77  ? 221 THR   R CG2 1 
ATOM   7558 N N   . VAL   E 5 372 ? 129.226 134.490 149.836 1.00 67.80  ? 222 VAL   R N   1 
ATOM   7559 C CA  . VAL   E 5 372 ? 130.023 133.827 150.862 1.00 67.80  ? 222 VAL   R CA  1 
ATOM   7560 C C   . VAL   E 5 372 ? 129.182 133.542 152.100 1.00 67.80  ? 222 VAL   R C   1 
ATOM   7561 O O   . VAL   E 5 372 ? 129.248 132.443 152.667 1.00 67.80  ? 222 VAL   R O   1 
ATOM   7562 C CB  . VAL   E 5 372 ? 131.286 134.643 151.194 1.00 67.80  ? 222 VAL   R CB  1 
ATOM   7563 C CG1 . VAL   E 5 372 ? 130.937 136.048 151.657 1.00 67.80  ? 222 VAL   R CG1 1 
ATOM   7564 C CG2 . VAL   E 5 372 ? 132.115 133.922 152.240 1.00 67.80  ? 222 VAL   R CG2 1 
ATOM   7565 N N   . LEU   E 5 373 ? 128.360 134.503 152.527 1.00 69.51  ? 223 LEU   R N   1 
ATOM   7566 C CA  . LEU   E 5 373 ? 127.554 134.294 153.721 1.00 69.51  ? 223 LEU   R CA  1 
ATOM   7567 C C   . LEU   E 5 373 ? 126.565 133.156 153.535 1.00 69.51  ? 223 LEU   R C   1 
ATOM   7568 O O   . LEU   E 5 373 ? 126.372 132.347 154.448 1.00 69.51  ? 223 LEU   R O   1 
ATOM   7569 C CB  . LEU   E 5 373 ? 126.828 135.582 154.106 1.00 69.51  ? 223 LEU   R CB  1 
ATOM   7570 C CG  . LEU   E 5 373 ? 127.543 136.483 155.119 1.00 69.51  ? 223 LEU   R CG  1 
ATOM   7571 C CD1 . LEU   E 5 373 ? 128.807 137.096 154.540 1.00 69.51  ? 223 LEU   R CD1 1 
ATOM   7572 C CD2 . LEU   E 5 373 ? 126.602 137.569 155.623 1.00 69.51  ? 223 LEU   R CD2 1 
ATOM   7573 N N   . VAL   E 5 374 ? 125.923 133.070 152.369 1.00 67.18  ? 224 VAL   R N   1 
ATOM   7574 C CA  . VAL   E 5 374 ? 124.976 131.982 152.158 1.00 67.18  ? 224 VAL   R CA  1 
ATOM   7575 C C   . VAL   E 5 374 ? 125.697 130.642 152.130 1.00 67.18  ? 224 VAL   R C   1 
ATOM   7576 O O   . VAL   E 5 374 ? 125.303 129.701 152.826 1.00 67.18  ? 224 VAL   R O   1 
ATOM   7577 C CB  . VAL   E 5 374 ? 124.148 132.216 150.886 1.00 67.18  ? 224 VAL   R CB  1 
ATOM   7578 C CG1 . VAL   E 5 374 ? 123.252 131.024 150.624 1.00 67.18  ? 224 VAL   R CG1 1 
ATOM   7579 C CG2 . VAL   E 5 374 ? 123.296 133.456 151.054 1.00 67.18  ? 224 VAL   R CG2 1 
ATOM   7580 N N   . PHE   E 5 375 ? 126.782 130.537 151.362 1.00 64.42  ? 225 PHE   R N   1 
ATOM   7581 C CA  . PHE   E 5 375 ? 127.489 129.260 151.301 1.00 64.42  ? 225 PHE   R CA  1 
ATOM   7582 C C   . PHE   E 5 375 ? 128.049 128.857 152.656 1.00 64.42  ? 225 PHE   R C   1 
ATOM   7583 O O   . PHE   E 5 375 ? 128.272 127.669 152.902 1.00 64.42  ? 225 PHE   R O   1 
ATOM   7584 C CB  . PHE   E 5 375 ? 128.613 129.325 150.270 1.00 64.42  ? 225 PHE   R CB  1 
ATOM   7585 C CG  . PHE   E 5 375 ? 129.766 128.410 150.571 1.00 64.42  ? 225 PHE   R CG  1 
ATOM   7586 C CD1 . PHE   E 5 375 ? 129.687 127.068 150.287 1.00 64.42  ? 225 PHE   R CD1 1 
ATOM   7587 C CD2 . PHE   E 5 375 ? 130.926 128.898 151.148 1.00 64.42  ? 225 PHE   R CD2 1 
ATOM   7588 C CE1 . PHE   E 5 375 ? 130.741 126.227 150.559 1.00 64.42  ? 225 PHE   R CE1 1 
ATOM   7589 C CE2 . PHE   E 5 375 ? 131.986 128.055 151.426 1.00 64.42  ? 225 PHE   R CE2 1 
ATOM   7590 C CZ  . PHE   E 5 375 ? 131.891 126.720 151.131 1.00 64.42  ? 225 PHE   R CZ  1 
ATOM   7591 N N   . LEU   E 5 376 ? 128.272 129.814 153.552 1.00 67.12  ? 226 LEU   R N   1 
ATOM   7592 C CA  . LEU   E 5 376 ? 128.846 129.465 154.845 1.00 67.12  ? 226 LEU   R CA  1 
ATOM   7593 C C   . LEU   E 5 376 ? 127.792 129.125 155.892 1.00 67.12  ? 226 LEU   R C   1 
ATOM   7594 O O   . LEU   E 5 376 ? 127.963 128.168 156.652 1.00 67.12  ? 226 LEU   R O   1 
ATOM   7595 C CB  . LEU   E 5 376 ? 129.730 130.604 155.349 1.00 67.12  ? 226 LEU   R CB  1 
ATOM   7596 C CG  . LEU   E 5 376 ? 130.438 130.323 156.673 1.00 67.12  ? 226 LEU   R CG  1 
ATOM   7597 C CD1 . LEU   E 5 376 ? 131.388 129.149 156.530 1.00 67.12  ? 226 LEU   R CD1 1 
ATOM   7598 C CD2 . LEU   E 5 376 ? 131.179 131.560 157.159 1.00 67.12  ? 226 LEU   R CD2 1 
ATOM   7599 N N   . LEU   E 5 377 ? 126.707 129.891 155.961 1.00 70.28  ? 227 LEU   R N   1 
ATOM   7600 C CA  . LEU   E 5 377 ? 125.706 129.706 157.001 1.00 70.28  ? 227 LEU   R CA  1 
ATOM   7601 C C   . LEU   E 5 377 ? 124.451 129.001 156.512 1.00 70.28  ? 227 LEU   R C   1 
ATOM   7602 O O   . LEU   E 5 377 ? 123.464 128.950 157.250 1.00 70.28  ? 227 LEU   R O   1 
ATOM   7603 C CB  . LEU   E 5 377 ? 125.329 131.052 157.619 1.00 70.28  ? 227 LEU   R CB  1 
ATOM   7604 C CG  . LEU   E 5 377 ? 126.436 131.767 158.397 1.00 70.28  ? 227 LEU   R CG  1 
ATOM   7605 C CD1 . LEU   E 5 377 ? 125.978 133.149 158.839 1.00 70.28  ? 227 LEU   R CD1 1 
ATOM   7606 C CD2 . LEU   E 5 377 ? 126.878 130.936 159.591 1.00 70.28  ? 227 LEU   R CD2 1 
ATOM   7607 N N   . CYS   E 5 378 ? 124.454 128.458 155.295 1.00 69.24  ? 228 CYS   R N   1 
ATOM   7608 C CA  . CYS   E 5 378 ? 123.323 127.670 154.839 1.00 69.24  ? 228 CYS   R CA  1 
ATOM   7609 C C   . CYS   E 5 378 ? 123.719 126.417 154.071 1.00 69.24  ? 228 CYS   R C   1 
ATOM   7610 O O   . CYS   E 5 378 ? 122.828 125.661 153.670 1.00 69.24  ? 228 CYS   R O   1 
ATOM   7611 C CB  . CYS   E 5 378 ? 122.400 128.526 153.962 1.00 69.24  ? 228 CYS   R CB  1 
ATOM   7612 S SG  . CYS   E 5 378 ? 121.591 129.888 154.830 1.00 69.24  ? 228 CYS   R SG  1 
ATOM   7613 N N   . GLY   E 5 379 ? 125.006 126.170 153.850 1.00 63.57  ? 229 GLY   R N   1 
ATOM   7614 C CA  . GLY   E 5 379 ? 125.411 125.041 153.036 1.00 63.57  ? 229 GLY   R CA  1 
ATOM   7615 C C   . GLY   E 5 379 ? 126.440 124.148 153.688 1.00 63.57  ? 229 GLY   R C   1 
ATOM   7616 O O   . GLY   E 5 379 ? 126.719 123.049 153.206 1.00 63.57  ? 229 GLY   R O   1 
ATOM   7617 N N   . LEU   E 5 380 ? 127.039 124.622 154.747 1.00 63.29  ? 230 LEU   R N   1 
ATOM   7618 C CA  . LEU   E 5 380 ? 127.937 123.778 155.515 1.00 63.29  ? 230 LEU   R CA  1 
ATOM   7619 C C   . LEU   E 5 380 ? 127.230 122.872 156.523 1.00 63.29  ? 230 LEU   R C   1 
ATOM   7620 O O   . LEU   E 5 380 ? 127.669 121.728 156.696 1.00 63.29  ? 230 LEU   R O   1 
ATOM   7621 C CB  . LEU   E 5 380 ? 128.986 124.626 156.223 1.00 63.29  ? 230 LEU   R CB  1 
ATOM   7622 C CG  . LEU   E 5 380 ? 130.299 124.601 155.455 1.00 63.29  ? 230 LEU   R CG  1 
ATOM   7623 C CD1 . LEU   E 5 380 ? 131.410 125.248 156.260 1.00 63.29  ? 230 LEU   R CD1 1 
ATOM   7624 C CD2 . LEU   E 5 380 ? 130.644 123.179 155.091 1.00 63.29  ? 230 LEU   R CD2 1 
ATOM   7625 N N   . PRO   E 5 381 ? 126.158 123.314 157.205 1.00 63.43  ? 231 PRO   R N   1 
ATOM   7626 C CA  . PRO   E 5 381 ? 125.610 122.488 158.294 1.00 63.43  ? 231 PRO   R CA  1 
ATOM   7627 C C   . PRO   E 5 381 ? 125.293 121.059 157.904 1.00 63.43  ? 231 PRO   R C   1 
ATOM   7628 O O   . PRO   E 5 381 ? 125.470 120.149 158.722 1.00 63.43  ? 231 PRO   R O   1 
ATOM   7629 C CB  . PRO   E 5 381 ? 124.342 123.250 158.692 1.00 63.43  ? 231 PRO   R CB  1 
ATOM   7630 C CG  . PRO   E 5 381 ? 124.671 124.647 158.427 1.00 63.43  ? 231 PRO   R CG  1 
ATOM   7631 C CD  . PRO   E 5 381 ? 125.511 124.639 157.183 1.00 63.43  ? 231 PRO   R CD  1 
ATOM   7632 N N   . PHE   E 5 382 ? 124.835 120.832 156.676 1.00 60.46  ? 232 PHE   R N   1 
ATOM   7633 C CA  . PHE   E 5 382 ? 124.489 119.480 156.258 1.00 60.46  ? 232 PHE   R CA  1 
ATOM   7634 C C   . PHE   E 5 382 ? 125.723 118.587 156.251 1.00 60.46  ? 232 PHE   R C   1 
ATOM   7635 O O   . PHE   E 5 382 ? 125.751 117.529 156.895 1.00 60.46  ? 232 PHE   R O   1 
ATOM   7636 C CB  . PHE   E 5 382 ? 123.839 119.550 154.879 1.00 60.46  ? 232 PHE   R CB  1 
ATOM   7637 C CG  . PHE   E 5 382 ? 123.381 118.239 154.340 1.00 60.46  ? 232 PHE   R CG  1 
ATOM   7638 C CD1 . PHE   E 5 382 ? 122.237 117.652 154.819 1.00 60.46  ? 232 PHE   R CD1 1 
ATOM   7639 C CD2 . PHE   E 5 382 ? 124.064 117.621 153.313 1.00 60.46  ? 232 PHE   R CD2 1 
ATOM   7640 C CE1 . PHE   E 5 382 ? 121.798 116.464 154.312 1.00 60.46  ? 232 PHE   R CE1 1 
ATOM   7641 C CE2 . PHE   E 5 382 ? 123.626 116.426 152.801 1.00 60.46  ? 232 PHE   R CE2 1 
ATOM   7642 C CZ  . PHE   E 5 382 ? 122.487 115.849 153.301 1.00 60.46  ? 232 PHE   R CZ  1 
ATOM   7643 N N   . GLY   E 5 383 ? 126.774 119.024 155.561 1.00 58.55  ? 233 GLY   R N   1 
ATOM   7644 C CA  . GLY   E 5 383 ? 127.996 118.250 155.504 1.00 58.55  ? 233 GLY   R CA  1 
ATOM   7645 C C   . GLY   E 5 383 ? 128.704 118.162 156.828 1.00 58.55  ? 233 GLY   R C   1 
ATOM   7646 O O   . GLY   E 5 383 ? 129.460 117.216 157.050 1.00 58.55  ? 233 GLY   R O   1 
ATOM   7647 N N   . ILE   E 5 384 ? 128.480 119.130 157.711 1.00 63.45  ? 234 ILE   R N   1 
ATOM   7648 C CA  . ILE   E 5 384 ? 129.079 119.106 159.039 1.00 63.45  ? 234 ILE   R CA  1 
ATOM   7649 C C   . ILE   E 5 384 ? 128.387 118.094 159.939 1.00 63.45  ? 234 ILE   R C   1 
ATOM   7650 O O   . ILE   E 5 384 ? 129.046 117.342 160.662 1.00 63.45  ? 234 ILE   R O   1 
ATOM   7651 C CB  . ILE   E 5 384 ? 129.057 120.516 159.656 1.00 63.45  ? 234 ILE   R CB  1 
ATOM   7652 C CG1 . ILE   E 5 384 ? 129.950 121.464 158.857 1.00 63.45  ? 234 ILE   R CG1 1 
ATOM   7653 C CG2 . ILE   E 5 384 ? 129.495 120.475 161.114 1.00 63.45  ? 234 ILE   R CG2 1 
ATOM   7654 C CD1 . ILE   E 5 384 ? 129.800 122.915 159.254 1.00 63.45  ? 234 ILE   R CD1 1 
ATOM   7655 N N   . LEU   E 5 385 ? 127.057 118.057 159.908 1.00 65.46  ? 235 LEU   R N   1 
ATOM   7656 C CA  . LEU   E 5 385 ? 126.341 117.025 160.641 1.00 65.46  ? 235 LEU   R CA  1 
ATOM   7657 C C   . LEU   E 5 385 ? 126.710 115.649 160.123 1.00 65.46  ? 235 LEU   R C   1 
ATOM   7658 O O   . LEU   E 5 385 ? 126.884 114.711 160.906 1.00 65.46  ? 235 LEU   R O   1 
ATOM   7659 C CB  . LEU   E 5 385 ? 124.835 117.251 160.536 1.00 65.46  ? 235 LEU   R CB  1 
ATOM   7660 C CG  . LEU   E 5 385 ? 123.949 116.141 161.106 1.00 65.46  ? 235 LEU   R CG  1 
ATOM   7661 C CD1 . LEU   E 5 385 ? 124.296 115.866 162.562 1.00 65.46  ? 235 LEU   R CD1 1 
ATOM   7662 C CD2 . LEU   E 5 385 ? 122.481 116.497 160.955 1.00 65.46  ? 235 LEU   R CD2 1 
ATOM   7663 N N   . GLY   E 5 386 ? 126.860 115.515 158.806 1.00 64.59  ? 236 GLY   R N   1 
ATOM   7664 C CA  . GLY   E 5 386 ? 127.177 114.215 158.242 1.00 64.59  ? 236 GLY   R CA  1 
ATOM   7665 C C   . GLY   E 5 386 ? 128.410 113.582 158.857 1.00 64.59  ? 236 GLY   R C   1 
ATOM   7666 O O   . GLY   E 5 386 ? 128.508 112.358 158.958 1.00 64.59  ? 236 GLY   R O   1 
ATOM   7667 N N   . ALA   E 5 387 ? 129.373 114.400 159.263 1.00 61.08  ? 237 ALA   R N   1 
ATOM   7668 C CA  . ALA   E 5 387 ? 130.581 113.849 159.854 1.00 61.08  ? 237 ALA   R CA  1 
ATOM   7669 C C   . ALA   E 5 387 ? 130.451 113.749 161.359 1.00 61.08  ? 237 ALA   R C   1 
ATOM   7670 O O   . ALA   E 5 387 ? 130.959 112.806 161.973 1.00 61.08  ? 237 ALA   R O   1 
ATOM   7671 C CB  . ALA   E 5 387 ? 131.788 114.702 159.475 1.00 61.08  ? 237 ALA   R CB  1 
ATOM   7672 N N   . LEU   E 5 388 ? 129.780 114.708 161.971 1.00 66.84  ? 238 LEU   R N   1 
ATOM   7673 C CA  . LEU   E 5 388 ? 129.573 114.666 163.408 1.00 66.84  ? 238 LEU   R CA  1 
ATOM   7674 C C   . LEU   E 5 388 ? 128.407 113.772 163.804 1.00 66.84  ? 238 LEU   R C   1 
ATOM   7675 O O   . LEU   E 5 388 ? 128.149 113.621 165.002 1.00 66.84  ? 238 LEU   R O   1 
ATOM   7676 C CB  . LEU   E 5 388 ? 129.347 116.081 163.945 1.00 66.84  ? 238 LEU   R CB  1 
ATOM   7677 C CG  . LEU   E 5 388 ? 130.563 116.868 164.447 1.00 66.84  ? 238 LEU   R CG  1 
ATOM   7678 C CD1 . LEU   E 5 388 ? 131.016 116.366 165.808 1.00 66.84  ? 238 LEU   R CD1 1 
ATOM   7679 C CD2 . LEU   E 5 388 ? 131.714 116.836 163.449 1.00 66.84  ? 238 LEU   R CD2 1 
ATOM   7680 N N   . ILE   E 5 389 ? 127.712 113.172 162.834 1.00 70.66  ? 239 ILE   R N   1 
ATOM   7681 C CA  . ILE   E 5 389 ? 126.531 112.370 163.142 1.00 70.66  ? 239 ILE   R CA  1 
ATOM   7682 C C   . ILE   E 5 389 ? 126.882 111.227 164.081 1.00 70.66  ? 239 ILE   R C   1 
ATOM   7683 O O   . ILE   E 5 389 ? 126.117 110.903 164.995 1.00 70.66  ? 239 ILE   R O   1 
ATOM   7684 C CB  . ILE   E 5 389 ? 125.871 111.856 161.846 1.00 70.66  ? 239 ILE   R CB  1 
ATOM   7685 C CG1 . ILE   E 5 389 ? 124.493 111.261 162.142 1.00 70.66  ? 239 ILE   R CG1 1 
ATOM   7686 C CG2 . ILE   E 5 389 ? 126.748 110.839 161.132 1.00 70.66  ? 239 ILE   R CG2 1 
ATOM   7687 C CD1 . ILE   E 5 389 ? 123.450 112.284 162.500 1.00 70.66  ? 239 ILE   R CD1 1 
ATOM   7688 N N   . TYR   E 5 390 ? 128.039 110.603 163.883 1.00 74.49  ? 240 TYR   R N   1 
ATOM   7689 C CA  . TYR   E 5 390 ? 128.442 109.478 164.702 1.00 74.49  ? 240 TYR   R CA  1 
ATOM   7690 C C   . TYR   E 5 390 ? 129.768 109.688 165.408 1.00 74.49  ? 240 TYR   R C   1 
ATOM   7691 O O   . TYR   E 5 390 ? 130.088 108.918 166.320 1.00 74.49  ? 240 TYR   R O   1 
ATOM   7692 C CB  . TYR   E 5 390 ? 128.496 108.197 163.860 1.00 74.49  ? 240 TYR   R CB  1 
ATOM   7693 C CG  . TYR   E 5 390 ? 127.124 107.628 163.583 1.00 74.49  ? 240 TYR   R CG  1 
ATOM   7694 C CD1 . TYR   E 5 390 ? 126.042 107.962 164.385 1.00 74.49  ? 240 TYR   R CD1 1 
ATOM   7695 C CD2 . TYR   E 5 390 ? 126.905 106.770 162.518 1.00 74.49  ? 240 TYR   R CD2 1 
ATOM   7696 C CE1 . TYR   E 5 390 ? 124.784 107.451 164.138 1.00 74.49  ? 240 TYR   R CE1 1 
ATOM   7697 C CE2 . TYR   E 5 390 ? 125.652 106.252 162.261 1.00 74.49  ? 240 TYR   R CE2 1 
ATOM   7698 C CZ  . TYR   E 5 390 ? 124.594 106.596 163.074 1.00 74.49  ? 240 TYR   R CZ  1 
ATOM   7699 O OH  . TYR   E 5 390 ? 123.342 106.083 162.823 1.00 74.49  ? 240 TYR   R OH  1 
ATOM   7700 N N   . ARG   E 5 391 ? 130.541 110.704 165.029 1.00 78.28  ? 241 ARG   R N   1 
ATOM   7701 C CA  . ARG   E 5 391 ? 131.686 111.083 165.845 1.00 78.28  ? 241 ARG   R CA  1 
ATOM   7702 C C   . ARG   E 5 391 ? 131.236 111.587 167.207 1.00 78.28  ? 241 ARG   R C   1 
ATOM   7703 O O   . ARG   E 5 391 ? 131.819 111.227 168.235 1.00 78.28  ? 241 ARG   R O   1 
ATOM   7704 C CB  . ARG   E 5 391 ? 132.519 112.142 165.127 1.00 78.28  ? 241 ARG   R CB  1 
ATOM   7705 C CG  . ARG   E 5 391 ? 133.395 111.592 164.012 1.00 78.28  ? 241 ARG   R CG  1 
ATOM   7706 C CD  . ARG   E 5 391 ? 134.579 110.815 164.573 1.00 78.28  ? 241 ARG   R CD  1 
ATOM   7707 N NE  . ARG   E 5 391 ? 134.272 109.401 164.773 1.00 78.28  ? 241 ARG   R NE  1 
ATOM   7708 C CZ  . ARG   E 5 391 ? 135.038 108.560 165.461 1.00 78.28  ? 241 ARG   R CZ  1 
ATOM   7709 N NH1 . ARG   E 5 391 ? 136.161 108.988 166.021 1.00 78.28  ? 241 ARG   R NH1 1 
ATOM   7710 N NH2 . ARG   E 5 391 ? 134.679 107.290 165.591 1.00 78.28  ? 241 ARG   R NH2 1 
ATOM   7711 N N   . MET   E 5 392 ? 130.195 112.411 167.236 1.00 76.26  ? 242 MET   R N   1 
ATOM   7712 C CA  . MET   E 5 392 ? 129.651 112.950 168.476 1.00 76.26  ? 242 MET   R CA  1 
ATOM   7713 C C   . MET   E 5 392 ? 128.427 112.132 168.858 1.00 76.26  ? 242 MET   R C   1 
ATOM   7714 O O   . MET   E 5 392 ? 127.418 112.143 168.148 1.00 76.26  ? 242 MET   R O   1 
ATOM   7715 C CB  . MET   E 5 392 ? 129.296 114.425 168.323 1.00 76.26  ? 242 MET   R CB  1 
ATOM   7716 N N   . HIS   E 5 393 ? 128.517 111.430 169.979 1.00 82.85  ? 243 HIS   R N   1 
ATOM   7717 C CA  . HIS   E 5 393 ? 127.432 110.603 170.491 1.00 82.85  ? 243 HIS   R CA  1 
ATOM   7718 C C   . HIS   E 5 393 ? 126.740 111.275 171.671 1.00 82.85  ? 243 HIS   R C   1 
ATOM   7719 O O   . HIS   E 5 393 ? 126.396 110.624 172.659 1.00 82.85  ? 243 HIS   R O   1 
ATOM   7720 C CB  . HIS   E 5 393 ? 127.947 109.222 170.887 1.00 82.85  ? 243 HIS   R CB  1 
ATOM   7721 N N   . LEU   E 5 394 ? 126.543 112.591 171.584 1.00 83.53  ? 244 LEU   R N   1 
ATOM   7722 C CA  . LEU   E 5 394 ? 126.025 113.364 172.707 1.00 83.53  ? 244 LEU   R CA  1 
ATOM   7723 C C   . LEU   E 5 394 ? 124.658 112.872 173.167 1.00 83.53  ? 244 LEU   R C   1 
ATOM   7724 O O   . LEU   E 5 394 ? 124.527 112.353 174.280 1.00 83.53  ? 244 LEU   R O   1 
ATOM   7725 C CB  . LEU   E 5 394 ? 125.947 114.846 172.334 1.00 83.53  ? 244 LEU   R CB  1 
ATOM   7726 N N   . ASN   E 5 395 ? 123.634 113.024 172.326 1.00 82.79  ? 245 ASN   R N   1 
ATOM   7727 C CA  . ASN   E 5 395 ? 122.293 112.542 172.671 1.00 82.79  ? 245 ASN   R CA  1 
ATOM   7728 C C   . ASN   E 5 395 ? 121.556 112.256 171.362 1.00 82.79  ? 245 ASN   R C   1 
ATOM   7729 O O   . ASN   E 5 395 ? 120.946 113.151 170.774 1.00 82.79  ? 245 ASN   R O   1 
ATOM   7730 C CB  . ASN   E 5 395 ? 121.543 113.549 173.530 1.00 82.79  ? 245 ASN   R CB  1 
ATOM   7731 N N   . LEU   E 5 396 ? 121.592 110.990 170.938 1.00 78.67  ? 246 LEU   R N   1 
ATOM   7732 C CA  . LEU   E 5 396 ? 121.025 110.630 169.643 1.00 78.67  ? 246 LEU   R CA  1 
ATOM   7733 C C   . LEU   E 5 396 ? 119.533 110.921 169.576 1.00 78.67  ? 246 LEU   R C   1 
ATOM   7734 O O   . LEU   E 5 396 ? 118.985 111.095 168.482 1.00 78.67  ? 246 LEU   R O   1 
ATOM   7735 C CB  . LEU   E 5 396 ? 121.289 109.154 169.346 1.00 78.67  ? 246 LEU   R CB  1 
ATOM   7736 N N   . GLU   E 5 397 ? 118.861 110.982 170.724 1.00 75.58  ? 247 GLU   R N   1 
ATOM   7737 C CA  . GLU   E 5 397 ? 117.420 111.205 170.720 1.00 75.58  ? 247 GLU   R CA  1 
ATOM   7738 C C   . GLU   E 5 397 ? 117.077 112.597 170.210 1.00 75.58  ? 247 GLU   R C   1 
ATOM   7739 O O   . GLU   E 5 397 ? 116.248 112.750 169.308 1.00 75.58  ? 247 GLU   R O   1 
ATOM   7740 C CB  . GLU   E 5 397 ? 116.855 110.989 172.124 1.00 75.58  ? 247 GLU   R CB  1 
ATOM   7741 N N   . VAL   E 5 398 ? 117.707 113.624 170.768 1.00 71.31  ? 248 VAL   R N   1 
ATOM   7742 C CA  . VAL   E 5 398 ? 117.372 114.985 170.376 1.00 71.31  ? 248 VAL   R CA  1 
ATOM   7743 C C   . VAL   E 5 398 ? 118.192 115.424 169.175 1.00 71.31  ? 248 VAL   R C   1 
ATOM   7744 O O   . VAL   E 5 398 ? 117.743 116.275 168.392 1.00 71.31  ? 248 VAL   R O   1 
ATOM   7745 C CB  . VAL   E 5 398 ? 117.565 115.948 171.558 1.00 71.31  ? 248 VAL   R CB  1 
ATOM   7746 N N   . LEU   E 5 399 ? 119.393 114.865 169.034 1.00 73.88  ? 249 LEU   R N   1 
ATOM   7747 C CA  . LEU   E 5 399 ? 120.226 115.142 167.876 1.00 73.88  ? 249 LEU   R CA  1 
ATOM   7748 C C   . LEU   E 5 399 ? 119.409 115.027 166.606 1.00 73.88  ? 249 LEU   R C   1 
ATOM   7749 O O   . LEU   E 5 399 ? 119.221 116.012 165.890 1.00 73.88  ? 249 LEU   R O   1 
ATOM   7750 C CB  . LEU   E 5 399 ? 121.421 114.185 167.853 1.00 73.88  ? 249 LEU   R CB  1 
ATOM   7751 C CG  . LEU   E 5 399 ? 122.548 114.401 166.839 1.00 73.88  ? 249 LEU   R CG  1 
ATOM   7752 C CD1 . LEU   E 5 399 ? 123.850 113.842 167.387 1.00 73.88  ? 249 LEU   R CD1 1 
ATOM   7753 C CD2 . LEU   E 5 399 ? 122.231 113.748 165.506 1.00 73.88  ? 249 LEU   R CD2 1 
ATOM   7754 N N   . TYR   E 5 400 ? 118.868 113.837 166.346 1.00 75.95  ? 250 TYR   R N   1 
ATOM   7755 C CA  . TYR   E 5 400 ? 118.091 113.603 165.137 1.00 75.95  ? 250 TYR   R CA  1 
ATOM   7756 C C   . TYR   E 5 400 ? 117.134 114.755 164.893 1.00 75.95  ? 250 TYR   R C   1 
ATOM   7757 O O   . TYR   E 5 400 ? 117.343 115.539 163.964 1.00 75.95  ? 250 TYR   R O   1 
ATOM   7758 C CB  . TYR   E 5 400 ? 117.314 112.286 165.235 1.00 75.95  ? 250 TYR   R CB  1 
ATOM   7759 C CG  . TYR   E 5 400 ? 116.463 111.957 164.018 1.00 75.95  ? 250 TYR   R CG  1 
ATOM   7760 C CD1 . TYR   E 5 400 ? 116.832 110.946 163.145 1.00 75.95  ? 250 TYR   R CD1 1 
ATOM   7761 C CD2 . TYR   E 5 400 ? 115.280 112.639 163.761 1.00 75.95  ? 250 TYR   R CD2 1 
ATOM   7762 C CE1 . TYR   E 5 400 ? 116.063 110.643 162.050 1.00 75.95  ? 250 TYR   R CE1 1 
ATOM   7763 C CE2 . TYR   E 5 400 ? 114.512 112.346 162.668 1.00 75.95  ? 250 TYR   R CE2 1 
ATOM   7764 C CZ  . TYR   E 5 400 ? 114.903 111.346 161.816 1.00 75.95  ? 250 TYR   R CZ  1 
ATOM   7765 O OH  . TYR   E 5 400 ? 114.123 111.051 160.725 1.00 75.95  ? 250 TYR   R OH  1 
ATOM   7766 N N   . CYS   E 5 401 ? 116.162 114.928 165.782 1.00 72.24  ? 251 CYS   R N   1 
ATOM   7767 C CA  . CYS   E 5 401 ? 115.093 115.883 165.545 1.00 72.24  ? 251 CYS   R CA  1 
ATOM   7768 C C   . CYS   E 5 401 ? 115.677 117.257 165.286 1.00 72.24  ? 251 CYS   R C   1 
ATOM   7769 O O   . CYS   E 5 401 ? 115.658 117.734 164.145 1.00 72.24  ? 251 CYS   R O   1 
ATOM   7770 C CB  . CYS   E 5 401 ? 114.132 115.926 166.734 1.00 72.24  ? 251 CYS   R CB  1 
ATOM   7771 N N   . HIS   E 5 402 ? 116.300 117.846 166.303 1.00 70.83  ? 252 HIS   R N   1 
ATOM   7772 C CA  . HIS   E 5 402 ? 116.746 119.225 166.164 1.00 70.83  ? 252 HIS   R CA  1 
ATOM   7773 C C   . HIS   E 5 402 ? 117.721 119.401 165.003 1.00 70.83  ? 252 HIS   R C   1 
ATOM   7774 O O   . HIS   E 5 402 ? 117.408 120.079 164.012 1.00 70.83  ? 252 HIS   R O   1 
ATOM   7775 C CB  . HIS   E 5 402 ? 117.389 119.707 167.465 1.00 70.83  ? 252 HIS   R CB  1 
ATOM   7776 N N   . VAL   E 5 403 ? 118.897 118.781 165.101 1.00 69.93  ? 253 VAL   R N   1 
ATOM   7777 C CA  . VAL   E 5 403 ? 119.952 119.156 164.177 1.00 69.93  ? 253 VAL   R CA  1 
ATOM   7778 C C   . VAL   E 5 403 ? 119.632 118.670 162.775 1.00 69.93  ? 253 VAL   R C   1 
ATOM   7779 O O   . VAL   E 5 403 ? 119.853 119.398 161.803 1.00 69.93  ? 253 VAL   R O   1 
ATOM   7780 C CB  . VAL   E 5 403 ? 121.335 118.673 164.665 1.00 69.93  ? 253 VAL   R CB  1 
ATOM   7781 C CG1 . VAL   E 5 403 ? 121.531 117.182 164.476 1.00 69.93  ? 253 VAL   R CG1 1 
ATOM   7782 C CG2 . VAL   E 5 403 ? 122.443 119.449 163.963 1.00 69.93  ? 253 VAL   R CG2 1 
ATOM   7783 N N   . TYR   E 5 404 ? 119.112 117.451 162.621 1.00 67.78  ? 254 TYR   R N   1 
ATOM   7784 C CA  . TYR   E 5 404 ? 118.865 117.002 161.264 1.00 67.78  ? 254 TYR   R CA  1 
ATOM   7785 C C   . TYR   E 5 404 ? 117.722 117.782 160.628 1.00 67.78  ? 254 TYR   R C   1 
ATOM   7786 O O   . TYR   E 5 404 ? 117.805 118.131 159.445 1.00 67.78  ? 254 TYR   R O   1 
ATOM   7787 C CB  . TYR   E 5 404 ? 118.612 115.500 161.227 1.00 67.78  ? 254 TYR   R CB  1 
ATOM   7788 C CG  . TYR   E 5 404 ? 118.744 114.909 159.843 1.00 67.78  ? 254 TYR   R CG  1 
ATOM   7789 C CD1 . TYR   E 5 404 ? 117.893 115.284 158.821 1.00 67.78  ? 254 TYR   R CD1 1 
ATOM   7790 C CD2 . TYR   E 5 404 ? 119.753 114.016 159.546 1.00 67.78  ? 254 TYR   R CD2 1 
ATOM   7791 C CE1 . TYR   E 5 404 ? 118.013 114.767 157.561 1.00 67.78  ? 254 TYR   R CE1 1 
ATOM   7792 C CE2 . TYR   E 5 404 ? 119.884 113.491 158.278 1.00 67.78  ? 254 TYR   R CE2 1 
ATOM   7793 C CZ  . TYR   E 5 404 ? 119.010 113.874 157.290 1.00 67.78  ? 254 TYR   R CZ  1 
ATOM   7794 O OH  . TYR   E 5 404 ? 119.133 113.357 156.024 1.00 67.78  ? 254 TYR   R OH  1 
ATOM   7795 N N   . LEU   E 5 405 ? 116.665 118.106 161.382 1.00 66.97  ? 255 LEU   R N   1 
ATOM   7796 C CA  . LEU   E 5 405 ? 115.615 118.914 160.781 1.00 66.97  ? 255 LEU   R CA  1 
ATOM   7797 C C   . LEU   E 5 405 ? 116.160 120.256 160.318 1.00 66.97  ? 255 LEU   R C   1 
ATOM   7798 O O   . LEU   E 5 405 ? 115.921 120.676 159.174 1.00 66.97  ? 255 LEU   R O   1 
ATOM   7799 C CB  . LEU   E 5 405 ? 114.469 119.109 161.771 1.00 66.97  ? 255 LEU   R CB  1 
ATOM   7800 C CG  . LEU   E 5 405 ? 113.446 117.972 161.837 1.00 66.97  ? 255 LEU   R CG  1 
ATOM   7801 C CD1 . LEU   E 5 405 ? 112.424 118.229 162.935 1.00 66.97  ? 255 LEU   R CD1 1 
ATOM   7802 C CD2 . LEU   E 5 405 ? 112.761 117.781 160.492 1.00 66.97  ? 255 LEU   R CD2 1 
ATOM   7803 N N   . VAL   E 5 406 ? 116.925 120.927 161.178 1.00 65.38  ? 256 VAL   R N   1 
ATOM   7804 C CA  . VAL   E 5 406 ? 117.422 122.247 160.817 1.00 65.38  ? 256 VAL   R CA  1 
ATOM   7805 C C   . VAL   E 5 406 ? 118.337 122.153 159.610 1.00 65.38  ? 256 VAL   R C   1 
ATOM   7806 O O   . VAL   E 5 406 ? 118.224 122.939 158.661 1.00 65.38  ? 256 VAL   R O   1 
ATOM   7807 C CB  . VAL   E 5 406 ? 118.130 122.899 162.019 1.00 65.38  ? 256 VAL   R CB  1 
ATOM   7808 C CG1 . VAL   E 5 406 ? 118.964 124.089 161.566 1.00 65.38  ? 256 VAL   R CG1 1 
ATOM   7809 C CG2 . VAL   E 5 406 ? 117.112 123.326 163.064 1.00 65.38  ? 256 VAL   R CG2 1 
ATOM   7810 N N   . CYS   E 5 407 ? 119.249 121.188 159.621 1.00 64.53  ? 257 CYS   R N   1 
ATOM   7811 C CA  . CYS   E 5 407 ? 120.233 121.093 158.555 1.00 64.53  ? 257 CYS   R CA  1 
ATOM   7812 C C   . CYS   E 5 407 ? 119.579 120.744 157.230 1.00 64.53  ? 257 CYS   R C   1 
ATOM   7813 O O   . CYS   E 5 407 ? 119.974 121.263 156.180 1.00 64.53  ? 257 CYS   R O   1 
ATOM   7814 C CB  . CYS   E 5 407 ? 121.295 120.062 158.924 1.00 64.53  ? 257 CYS   R CB  1 
ATOM   7815 S SG  . CYS   E 5 407 ? 122.390 120.581 160.262 1.00 64.53  ? 257 CYS   R SG  1 
ATOM   7816 N N   . MET   E 5 408 ? 118.582 119.864 157.251 1.00 65.24  ? 258 MET   R N   1 
ATOM   7817 C CA  . MET   E 5 408 ? 117.899 119.522 156.015 1.00 65.24  ? 258 MET   R CA  1 
ATOM   7818 C C   . MET   E 5 408 ? 117.175 120.731 155.452 1.00 65.24  ? 258 MET   R C   1 
ATOM   7819 O O   . MET   E 5 408 ? 117.252 121.011 154.249 1.00 65.24  ? 258 MET   R O   1 
ATOM   7820 C CB  . MET   E 5 408 ? 116.922 118.377 156.257 1.00 65.24  ? 258 MET   R CB  1 
ATOM   7821 C CG  . MET   E 5 408 ? 116.182 117.937 155.017 1.00 65.24  ? 258 MET   R CG  1 
ATOM   7822 S SD  . MET   E 5 408 ? 117.147 118.068 153.501 1.00 65.24  ? 258 MET   R SD  1 
ATOM   7823 C CE  . MET   E 5 408 ? 118.536 116.990 153.837 1.00 65.24  ? 258 MET   R CE  1 
ATOM   7824 N N   . SER   E 5 409 ? 116.481 121.478 156.310 1.00 66.13  ? 259 SER   R N   1 
ATOM   7825 C CA  . SER   E 5 409 ? 115.782 122.660 155.820 1.00 66.13  ? 259 SER   R CA  1 
ATOM   7826 C C   . SER   E 5 409 ? 116.761 123.662 155.221 1.00 66.13  ? 259 SER   R C   1 
ATOM   7827 O O   . SER   E 5 409 ? 116.510 124.236 154.154 1.00 66.13  ? 259 SER   R O   1 
ATOM   7828 C CB  . SER   E 5 409 ? 114.974 123.297 156.951 1.00 66.13  ? 259 SER   R CB  1 
ATOM   7829 O OG  . SER   E 5 409 ? 114.249 124.422 156.488 1.00 66.13  ? 259 SER   R OG  1 
ATOM   7830 N N   . LEU   E 5 410 ? 117.891 123.882 155.893 1.00 64.31  ? 260 LEU   R N   1 
ATOM   7831 C CA  . LEU   E 5 410 ? 118.844 124.875 155.411 1.00 64.31  ? 260 LEU   R CA  1 
ATOM   7832 C C   . LEU   E 5 410 ? 119.494 124.443 154.104 1.00 64.31  ? 260 LEU   R C   1 
ATOM   7833 O O   . LEU   E 5 410 ? 119.720 125.274 153.218 1.00 64.31  ? 260 LEU   R O   1 
ATOM   7834 C CB  . LEU   E 5 410 ? 119.901 125.150 156.475 1.00 64.31  ? 260 LEU   R CB  1 
ATOM   7835 C CG  . LEU   E 5 410 ? 119.401 125.877 157.721 1.00 64.31  ? 260 LEU   R CG  1 
ATOM   7836 C CD1 . LEU   E 5 410 ? 120.547 126.588 158.424 1.00 64.31  ? 260 LEU   R CD1 1 
ATOM   7837 C CD2 . LEU   E 5 410 ? 118.307 126.861 157.353 1.00 64.31  ? 260 LEU   R CD2 1 
ATOM   7838 N N   . SER   E 5 411 ? 119.820 123.156 153.969 1.00 62.59  ? 261 SER   R N   1 
ATOM   7839 C CA  . SER   E 5 411 ? 120.358 122.667 152.705 1.00 62.59  ? 261 SER   R CA  1 
ATOM   7840 C C   . SER   E 5 411 ? 119.343 122.827 151.584 1.00 62.59  ? 261 SER   R C   1 
ATOM   7841 O O   . SER   E 5 411 ? 119.697 123.200 150.458 1.00 62.59  ? 261 SER   R O   1 
ATOM   7842 C CB  . SER   E 5 411 ? 120.776 121.206 152.847 1.00 62.59  ? 261 SER   R CB  1 
ATOM   7843 O OG  . SER   E 5 411 ? 119.648 120.378 153.074 1.00 62.59  ? 261 SER   R OG  1 
ATOM   7844 N N   . SER   E 5 412 ? 118.072 122.551 151.876 1.00 64.39  ? 262 SER   R N   1 
ATOM   7845 C CA  . SER   E 5 412 ? 117.031 122.767 150.881 1.00 64.39  ? 262 SER   R CA  1 
ATOM   7846 C C   . SER   E 5 412 ? 116.963 124.227 150.463 1.00 64.39  ? 262 SER   R C   1 
ATOM   7847 O O   . SER   E 5 412 ? 116.837 124.532 149.273 1.00 64.39  ? 262 SER   R O   1 
ATOM   7848 C CB  . SER   E 5 412 ? 115.680 122.300 151.425 1.00 64.39  ? 262 SER   R CB  1 
ATOM   7849 O OG  . SER   E 5 412 ? 114.646 122.526 150.484 1.00 64.39  ? 262 SER   R OG  1 
ATOM   7850 N N   . LEU   E 5 413 ? 117.048 125.146 151.423 1.00 64.88  ? 263 LEU   R N   1 
ATOM   7851 C CA  . LEU   E 5 413 ? 116.995 126.567 151.088 1.00 64.88  ? 263 LEU   R CA  1 
ATOM   7852 C C   . LEU   E 5 413 ? 118.188 126.982 150.236 1.00 64.88  ? 263 LEU   R C   1 
ATOM   7853 O O   . LEU   E 5 413 ? 118.044 127.727 149.259 1.00 64.88  ? 263 LEU   R O   1 
ATOM   7854 C CB  . LEU   E 5 413 ? 116.933 127.407 152.362 1.00 64.88  ? 263 LEU   R CB  1 
ATOM   7855 C CG  . LEU   E 5 413 ? 116.880 128.920 152.142 1.00 64.88  ? 263 LEU   R CG  1 
ATOM   7856 C CD1 . LEU   E 5 413 ? 115.612 129.313 151.399 1.00 64.88  ? 263 LEU   R CD1 1 
ATOM   7857 C CD2 . LEU   E 5 413 ? 116.981 129.660 153.468 1.00 64.88  ? 263 LEU   R CD2 1 
ATOM   7858 N N   . ASN   E 5 414 ? 119.383 126.535 150.620 1.00 63.00  ? 264 ASN   R N   1 
ATOM   7859 C CA  . ASN   E 5 414 ? 120.576 126.721 149.801 1.00 63.00  ? 264 ASN   R CA  1 
ATOM   7860 C C   . ASN   E 5 414 ? 120.314 126.325 148.355 1.00 63.00  ? 264 ASN   R C   1 
ATOM   7861 O O   . ASN   E 5 414 ? 120.511 127.119 147.424 1.00 63.00  ? 264 ASN   R O   1 
ATOM   7862 C CB  . ASN   E 5 414 ? 121.716 125.890 150.402 1.00 63.00  ? 264 ASN   R CB  1 
ATOM   7863 C CG  . ASN   E 5 414 ? 122.989 125.898 149.561 1.00 63.00  ? 264 ASN   R CG  1 
ATOM   7864 O OD1 . ASN   E 5 414 ? 122.961 125.885 148.335 1.00 63.00  ? 264 ASN   R OD1 1 
ATOM   7865 N ND2 . ASN   E 5 414 ? 124.125 125.916 150.240 1.00 63.00  ? 264 ASN   R ND2 1 
ATOM   7866 N N   . SER   E 5 415 ? 119.920 125.070 148.154 1.00 61.85  ? 265 SER   R N   1 
ATOM   7867 C CA  . SER   E 5 415 ? 119.734 124.565 146.808 1.00 61.85  ? 265 SER   R CA  1 
ATOM   7868 C C   . SER   E 5 415 ? 118.625 125.295 146.076 1.00 61.85  ? 265 SER   R C   1 
ATOM   7869 O O   . SER   E 5 415 ? 118.675 125.407 144.848 1.00 61.85  ? 265 SER   R O   1 
ATOM   7870 C CB  . SER   E 5 415 ? 119.440 123.068 146.849 1.00 61.85  ? 265 SER   R CB  1 
ATOM   7871 O OG  . SER   E 5 415 ? 118.887 122.628 145.622 1.00 61.85  ? 265 SER   R OG  1 
ATOM   7872 N N   . SER   E 5 416 ? 117.628 125.796 146.798 1.00 66.12  ? 266 SER   R N   1 
ATOM   7873 C CA  . SER   E 5 416 ? 116.540 126.520 146.157 1.00 66.12  ? 266 SER   R CA  1 
ATOM   7874 C C   . SER   E 5 416 ? 116.963 127.910 145.715 1.00 66.12  ? 266 SER   R C   1 
ATOM   7875 O O   . SER   E 5 416 ? 116.453 128.418 144.713 1.00 66.12  ? 266 SER   R O   1 
ATOM   7876 C CB  . SER   E 5 416 ? 115.346 126.619 147.109 1.00 66.12  ? 266 SER   R CB  1 
ATOM   7877 O OG  . SER   E 5 416 ? 114.356 127.494 146.598 1.00 66.12  ? 266 SER   R OG  1 
ATOM   7878 N N   . ALA   E 5 417 ? 117.887 128.534 146.439 1.00 66.00  ? 267 ALA   R N   1 
ATOM   7879 C CA  . ALA   E 5 417 ? 118.266 129.912 146.170 1.00 66.00  ? 267 ALA   R CA  1 
ATOM   7880 C C   . ALA   E 5 417 ? 119.473 130.047 145.253 1.00 66.00  ? 267 ALA   R C   1 
ATOM   7881 O O   . ALA   E 5 417 ? 119.680 131.126 144.689 1.00 66.00  ? 267 ALA   R O   1 
ATOM   7882 C CB  . ALA   E 5 417 ? 118.541 130.648 147.486 1.00 66.00  ? 267 ALA   R CB  1 
ATOM   7883 N N   . ASN   E 5 418 ? 120.271 128.992 145.085 1.00 64.73  ? 268 ASN   R N   1 
ATOM   7884 C CA  . ASN   E 5 418 ? 121.508 129.139 144.320 1.00 64.73  ? 268 ASN   R CA  1 
ATOM   7885 C C   . ASN   E 5 418 ? 121.287 129.645 142.899 1.00 64.73  ? 268 ASN   R C   1 
ATOM   7886 O O   . ASN   E 5 418 ? 121.860 130.698 142.544 1.00 64.73  ? 268 ASN   R O   1 
ATOM   7887 C CB  . ASN   E 5 418 ? 122.266 127.812 144.328 1.00 64.73  ? 268 ASN   R CB  1 
ATOM   7888 C CG  . ASN   E 5 418 ? 122.951 127.553 145.633 1.00 64.73  ? 268 ASN   R CG  1 
ATOM   7889 O OD1 . ASN   E 5 418 ? 122.875 128.361 146.555 1.00 64.73  ? 268 ASN   R OD1 1 
ATOM   7890 N ND2 . ASN   E 5 418 ? 123.629 126.419 145.729 1.00 64.73  ? 268 ASN   R ND2 1 
ATOM   7891 N N   . PRO   E 5 419 ? 120.489 128.990 142.049 1.00 67.45  ? 269 PRO   R N   1 
ATOM   7892 C CA  . PRO   E 5 419 ? 120.315 129.510 140.689 1.00 67.45  ? 269 PRO   R CA  1 
ATOM   7893 C C   . PRO   E 5 419 ? 119.741 130.903 140.658 1.00 67.45  ? 269 PRO   R C   1 
ATOM   7894 O O   . PRO   E 5 419 ? 120.083 131.669 139.753 1.00 67.45  ? 269 PRO   R O   1 
ATOM   7895 C CB  . PRO   E 5 419 ? 119.363 128.497 140.041 1.00 67.45  ? 269 PRO   R CB  1 
ATOM   7896 C CG  . PRO   E 5 419 ? 118.652 127.873 141.172 1.00 67.45  ? 269 PRO   R CG  1 
ATOM   7897 C CD  . PRO   E 5 419 ? 119.656 127.795 142.270 1.00 67.45  ? 269 PRO   R CD  1 
ATOM   7898 N N   . ILE   E 5 420 ? 118.901 131.270 141.627 1.00 69.17  ? 270 ILE   R N   1 
ATOM   7899 C CA  . ILE   E 5 420 ? 118.289 132.593 141.610 1.00 69.17  ? 270 ILE   R CA  1 
ATOM   7900 C C   . ILE   E 5 420 ? 119.357 133.672 141.678 1.00 69.17  ? 270 ILE   R C   1 
ATOM   7901 O O   . ILE   E 5 420 ? 119.437 134.543 140.804 1.00 69.17  ? 270 ILE   R O   1 
ATOM   7902 C CB  . ILE   E 5 420 ? 117.279 132.731 142.762 1.00 69.17  ? 270 ILE   R CB  1 
ATOM   7903 C CG1 . ILE   E 5 420 ? 116.148 131.712 142.607 1.00 69.17  ? 270 ILE   R CG1 1 
ATOM   7904 C CG2 . ILE   E 5 420 ? 116.731 134.149 142.821 1.00 69.17  ? 270 ILE   R CG2 1 
ATOM   7905 C CD1 . ILE   E 5 420 ? 115.130 131.755 143.726 1.00 69.17  ? 270 ILE   R CD1 1 
ATOM   7906 N N   . ILE   E 5 421 ? 120.233 133.595 142.679 1.00 65.56  ? 271 ILE   R N   1 
ATOM   7907 C CA  . ILE   E 5 421 ? 121.257 134.616 142.850 1.00 65.56  ? 271 ILE   R CA  1 
ATOM   7908 C C   . ILE   E 5 421 ? 122.351 134.535 141.794 1.00 65.56  ? 271 ILE   R C   1 
ATOM   7909 O O   . ILE   E 5 421 ? 122.945 135.567 141.456 1.00 65.56  ? 271 ILE   R O   1 
ATOM   7910 C CB  . ILE   E 5 421 ? 121.872 134.556 144.261 1.00 65.56  ? 271 ILE   R CB  1 
ATOM   7911 C CG1 . ILE   E 5 421 ? 122.684 135.818 144.544 1.00 65.56  ? 271 ILE   R CG1 1 
ATOM   7912 C CG2 . ILE   E 5 421 ? 122.734 133.345 144.420 1.00 65.56  ? 271 ILE   R CG2 1 
ATOM   7913 C CD1 . ILE   E 5 421 ? 121.849 137.080 144.608 1.00 65.56  ? 271 ILE   R CD1 1 
ATOM   7914 N N   . TYR   E 5 422 ? 122.629 133.353 141.244 1.00 62.87  ? 272 TYR   R N   1 
ATOM   7915 C CA  . TYR   E 5 422 ? 123.679 133.295 140.236 1.00 62.87  ? 272 TYR   R CA  1 
ATOM   7916 C C   . TYR   E 5 422 ? 123.202 133.592 138.819 1.00 62.87  ? 272 TYR   R C   1 
ATOM   7917 O O   . TYR   E 5 422 ? 124.034 133.887 137.957 1.00 62.87  ? 272 TYR   R O   1 
ATOM   7918 C CB  . TYR   E 5 422 ? 124.368 131.929 140.259 1.00 62.87  ? 272 TYR   R CB  1 
ATOM   7919 C CG  . TYR   E 5 422 ? 125.287 131.748 141.438 1.00 62.87  ? 272 TYR   R CG  1 
ATOM   7920 C CD1 . TYR   E 5 422 ? 124.792 131.343 142.664 1.00 62.87  ? 272 TYR   R CD1 1 
ATOM   7921 C CD2 . TYR   E 5 422 ? 126.644 131.999 141.331 1.00 62.87  ? 272 TYR   R CD2 1 
ATOM   7922 C CE1 . TYR   E 5 422 ? 125.616 131.186 143.749 1.00 62.87  ? 272 TYR   R CE1 1 
ATOM   7923 C CE2 . TYR   E 5 422 ? 127.475 131.842 142.410 1.00 62.87  ? 272 TYR   R CE2 1 
ATOM   7924 C CZ  . TYR   E 5 422 ? 126.952 131.438 143.619 1.00 62.87  ? 272 TYR   R CZ  1 
ATOM   7925 O OH  . TYR   E 5 422 ? 127.768 131.272 144.703 1.00 62.87  ? 272 TYR   R OH  1 
ATOM   7926 N N   . PHE   E 5 423 ? 121.925 133.515 138.544 1.00 71.44  ? 273 PHE   R N   1 
ATOM   7927 C CA  . PHE   E 5 423 ? 121.525 133.690 137.154 1.00 71.44  ? 273 PHE   R CA  1 
ATOM   7928 C C   . PHE   E 5 423 ? 120.422 134.714 136.962 1.00 71.44  ? 273 PHE   R C   1 
ATOM   7929 O O   . PHE   E 5 423 ? 120.427 135.427 135.957 1.00 71.44  ? 273 PHE   R O   1 
ATOM   7930 C CB  . PHE   E 5 423 ? 121.077 132.351 136.576 1.00 71.44  ? 273 PHE   R CB  1 
ATOM   7931 C CG  . PHE   E 5 423 ? 120.683 132.418 135.134 1.00 71.44  ? 273 PHE   R CG  1 
ATOM   7932 C CD1 . PHE   E 5 423 ? 121.644 132.500 134.145 1.00 71.44  ? 273 PHE   R CD1 1 
ATOM   7933 C CD2 . PHE   E 5 423 ? 119.349 132.412 134.768 1.00 71.44  ? 273 PHE   R CD2 1 
ATOM   7934 C CE1 . PHE   E 5 423 ? 121.285 132.565 132.816 1.00 71.44  ? 273 PHE   R CE1 1 
ATOM   7935 C CE2 . PHE   E 5 423 ? 118.981 132.476 133.437 1.00 71.44  ? 273 PHE   R CE2 1 
ATOM   7936 C CZ  . PHE   E 5 423 ? 119.952 132.553 132.460 1.00 71.44  ? 273 PHE   R CZ  1 
ATOM   7937 N N   . PHE   E 5 424 ? 119.470 134.804 137.893 1.00 75.67  ? 274 PHE   R N   1 
ATOM   7938 C CA  . PHE   E 5 424 ? 118.307 135.657 137.687 1.00 75.67  ? 274 PHE   R CA  1 
ATOM   7939 C C   . PHE   E 5 424 ? 118.643 137.138 137.762 1.00 75.67  ? 274 PHE   R C   1 
ATOM   7940 O O   . PHE   E 5 424 ? 117.775 137.967 137.467 1.00 75.67  ? 274 PHE   R O   1 
ATOM   7941 C CB  . PHE   E 5 424 ? 117.223 135.325 138.716 1.00 75.67  ? 274 PHE   R CB  1 
ATOM   7942 C CG  . PHE   E 5 424 ? 116.558 133.992 138.496 1.00 75.67  ? 274 PHE   R CG  1 
ATOM   7943 C CD1 . PHE   E 5 424 ? 116.819 133.243 137.361 1.00 75.67  ? 274 PHE   R CD1 1 
ATOM   7944 C CD2 . PHE   E 5 424 ? 115.666 133.492 139.429 1.00 75.67  ? 274 PHE   R CD2 1 
ATOM   7945 C CE1 . PHE   E 5 424 ? 116.208 132.022 137.165 1.00 75.67  ? 274 PHE   R CE1 1 
ATOM   7946 C CE2 . PHE   E 5 424 ? 115.052 132.271 139.237 1.00 75.67  ? 274 PHE   R CE2 1 
ATOM   7947 C CZ  . PHE   E 5 424 ? 115.324 131.536 138.103 1.00 75.67  ? 274 PHE   R CZ  1 
ATOM   7948 N N   . VAL   E 5 425 ? 119.865 137.490 138.145 1.00 73.60  ? 275 VAL   R N   1 
ATOM   7949 C CA  . VAL   E 5 425 ? 120.242 138.884 138.326 1.00 73.60  ? 275 VAL   R CA  1 
ATOM   7950 C C   . VAL   E 5 425 ? 120.807 139.435 137.024 1.00 73.60  ? 275 VAL   R C   1 
ATOM   7951 O O   . VAL   E 5 425 ? 121.440 140.496 137.008 1.00 73.60  ? 275 VAL   R O   1 
ATOM   7952 C CB  . VAL   E 5 425 ? 121.251 139.035 139.475 1.00 73.60  ? 275 VAL   R CB  1 
ATOM   7953 C CG1 . VAL   E 5 425 ? 120.646 138.516 140.763 1.00 73.60  ? 275 VAL   R CG1 1 
ATOM   7954 C CG2 . VAL   E 5 425 ? 122.534 138.290 139.151 1.00 73.60  ? 275 VAL   R CG2 1 
ATOM   7955 N N   . GLY   E 5 426 ? 120.580 138.720 135.928 1.00 73.03  ? 276 GLY   R N   1 
ATOM   7956 C CA  . GLY   E 5 426 ? 121.072 139.140 134.631 1.00 73.03  ? 276 GLY   R CA  1 
ATOM   7957 C C   . GLY   E 5 426 ? 120.815 138.120 133.540 1.00 73.03  ? 276 GLY   R C   1 
ATOM   7958 O O   . GLY   E 5 426 ? 119.889 137.315 133.635 1.00 73.03  ? 276 GLY   R O   1 
HETATM 7959 C C1  . A1LZU F 6 .   ? 115.797 105.623 159.984 1.00 84.12  ? 501 A1LZU R C1  1 
HETATM 7960 C C10 . A1LZU F 6 .   ? 119.673 109.908 159.530 1.00 84.12  ? 501 A1LZU R C10 1 
HETATM 7961 C C11 . A1LZU F 6 .   ? 120.404 109.101 158.460 1.00 84.12  ? 501 A1LZU R C11 1 
HETATM 7962 C C12 . A1LZU F 6 .   ? 120.670 110.775 160.294 1.00 84.12  ? 501 A1LZU R C12 1 
HETATM 7963 C C13 . A1LZU F 6 .   ? 116.282 109.833 158.726 1.00 84.12  ? 501 A1LZU R C13 1 
HETATM 7964 C C2  . A1LZU F 6 .   ? 115.607 107.012 160.588 1.00 84.12  ? 501 A1LZU R C2  1 
HETATM 7965 C C3  . A1LZU F 6 .   ? 114.633 106.948 161.763 1.00 84.12  ? 501 A1LZU R C3  1 
HETATM 7966 C C4  . A1LZU F 6 .   ? 116.933 107.627 160.986 1.00 84.12  ? 501 A1LZU R C4  1 
HETATM 7967 C C5  . A1LZU F 6 .   ? 117.661 108.451 160.125 1.00 84.12  ? 501 A1LZU R C5  1 
HETATM 7968 C C6  . A1LZU F 6 .   ? 118.891 109.015 160.471 1.00 84.12  ? 501 A1LZU R C6  1 
HETATM 7969 C C7  . A1LZU F 6 .   ? 119.378 108.733 161.745 1.00 84.12  ? 501 A1LZU R C7  1 
HETATM 7970 C C8  . A1LZU F 6 .   ? 118.688 107.926 162.621 1.00 84.12  ? 501 A1LZU R C8  1 
HETATM 7971 C C9  . A1LZU F 6 .   ? 117.481 107.381 162.242 1.00 84.12  ? 501 A1LZU R C9  1 
HETATM 7972 O O1  . A1LZU F 6 .   ? 117.134 108.704 158.870 1.00 84.12  ? 501 A1LZU R O1  1 
HETATM 7973 O O2  . A1LZU F 6 .   ? 115.462 109.784 157.589 1.00 84.12  ? 501 A1LZU R O2  1 
HETATM 7974 O O3  . A1LZU F 6 .   ? 113.520 110.415 156.139 1.00 84.12  ? 501 A1LZU R O3  1 
HETATM 7975 O O4  . A1LZU F 6 .   ? 113.465 110.873 158.617 1.00 84.12  ? 501 A1LZU R O4  1 
HETATM 7976 O O5  . A1LZU F 6 .   ? 115.003 112.200 157.123 1.00 84.12  ? 501 A1LZU R O5  1 
HETATM 7977 P P1  . A1LZU F 6 .   ? 114.297 110.880 157.352 1.00 84.12  ? 501 A1LZU R P1  1 
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