#### Hu-mAb output ####

    input sequence: EVKLLESGGGLVQPGGSMRLSCAGSGFTFTDFYMNWIRQPAGKAPEWLGFIRDKAKGYTTEYNPSVKGRFTISRDNTQNMLYLQMNTLRAEDTATYYCAREGHTAAPFDYWGQGVMVTVSS
humanised sequence: QVKLLESGPGLVKPSETMRLTCAGSGFTFTDFYWNWIRQPAGKAPEWLGFIRDKAKGYTTEYNPSLKGRFTISVDTTQNMFSLQMNTVTAADTATYYCAREGHTAAPFDYWGQGVMVTVSS

   v-gene selected: hv4
     initial score: 0.000
         threshold: 0.835


## Mutation List ##

1	Residue 39 	M --> W	0.0450
2	Residue 1 	E --> Q	0.0900
3	Residue 97 	E --> A	0.1600
4	Residue 16 	G --> S	0.2300
5	Residue 80 	R --> V	0.3150
6	Residue 17 	G --> E	0.3750
7	Residue 88 	Y --> S	0.4250
8	Residue 87 	L --> F	0.4900
9	Residue 18 	S --> T	0.5350
10	Residue 95 	R --> T	0.5950
11	Residue 94 	L --> V	0.6600
12	Residue 22 	S --> T	0.7150
13	Residue 14 	Q --> K	0.7650
14	Residue 9 	G --> P	0.7950
15	Residue 71 	V --> L	0.8300
16	Residue 82 	N --> T	0.8550


## Numbered Output ##

  resno  in   out
      1   E --> Q  
      2   V     V  
      3   K     K  
      4   L     L  
      5   L     L  
      6   E     E  
      7   S     S  
      8   G     G  
      9   G --> P  
     11   G     G  
     12   L     L  
     13   V     V  
     14   Q --> K  
     15   P     P  
     16   G --> S  
     17   G --> E  
     18   S --> T  
     19   M     M  
     20   R     R  
     21   L     L  
     22   S --> T  
     23   C     C  
     24   A     A  
     25   G     G  
     26   S     S  
     27   G     G  CDR1
     28   F     F  CDR1
     29   T     T  CDR1
     30   F     F  CDR1
     35   T     T  CDR1
     36   D     D  CDR1
     37   F     F  CDR1
     38   Y     Y  CDR1
     39   M --> W  
     40   N     N  
     41   W     W  
     42   I     I  
     43   R     R  
     44   Q     Q  
     45   P     P  
     46   A     A  
     47   G     G  
     48   K     K  
     49   A     A  
     50   P     P  
     51   E     E  
     52   W     W  
     53   L     L  
     54   G     G  
     55   F     F  
     56   I     I  CDR2
     57   R     R  CDR2
     58   D     D  CDR2
     59   K     K  CDR2
     60   A     A  CDR2
     61   K     K  CDR2
     62   G     G  CDR2
     63   Y     Y  CDR2
     64   T     T  CDR2
     65   T     T  CDR2
     66   E     E  
     67   Y     Y  
     68   N     N  
     69   P     P  
     70   S     S  
     71   V --> L  
     72   K     K  
     74   G     G  
     75   R     R  
     76   F     F  
     77   T     T  
     78   I     I  
     79   S     S  
     80   R --> V  
     81   D     D  
     82   N --> T  
     83   T     T  
     84   Q     Q  
     85   N     N  
     86   M     M  
     87   L --> F  
     88   Y --> S  
     89   L     L  
     90   Q     Q  
     91   M     M  
     92   N     N  
     93   T     T  
     94   L --> V  
     95   R --> T  
     96   A     A  
     97   E --> A  
     98   D     D  
     99   T     T  
    100   A     A  
    101   T     T  
    102   Y     Y  
    103   Y     Y  
    104   C     C  
    105   A     A  CDR3
    106   R     R  CDR3
    107   E     E  CDR3
    108   G     G  CDR3
    109   H     H  CDR3
    110   T     T  CDR3
    112   A     A  CDR3
    113   A     A  CDR3
    114   P     P  CDR3
    115   F     F  CDR3
    116   D     D  CDR3
    117   Y     Y  CDR3
    118   W     W  
    119   G     G  
    120   Q     Q  
    121   G     G  
    122   V     V  
    123   M     M  
    124   V     V  
    125   T     T  
    126   V     V  
    127   S     S  
    128   S     S