pdb Bchain Achain Dchain Gchain TCRtype model antigen_chain antigen_type antigen_name antigen_het_name mhc_type mhc_chain1 mhc_chain2 docking_angle beta_subgroup alpha_subgroup gamma_subgroup delta_subgroup short_header date compound beta_organism alpha_organism gamma_organism delta_organism antigen_organism mhc_chain1_organism mhc_chain2_organism authors resolution method r_free r_factor affinity affinity_method affinity_temperature affinity_pmid engineered 8trq E D NA NA abTCR 0 C peptide vimentin NA GB B NA nan TRBV19 TRAV6 NA NA IMMUNE SYSTEM 07/31/24 T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 mus musculus mus musculus homo sapiens homo sapiens Loh, T.J., Lim, J.J., Reid, H.H., Rossjohn, J. 2.75 X-RAY DIFFRACTION 0.264 0.216 True 3qux D C NA NA abTCR 0 A Hapten N-[(3S,4S,5R)-4,5-DIHYDROXY-1-[(2R,3R,4R,5R,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]NONADECAN-3-YL]HEXACOSANAMIDE QUX CD1 A B 25.713 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 06/29/11 Structure of the mouse CD1d-alpha-C-GalCer-iNKT TCR complex mus musculus mus musculus mus musculus mus musculus mus musculus Li, Y., Girardi, E., Yu, E.D., Zajonc, D.M. 2.91 X-RAY DIFFRACTION 0.252 0.208 True 4ozi H G NA NA abTCR 0 J peptide deamidated gliadin-alpha1 peptide NA MH2 A B 45.767 TRBV20 TRAV4 NA NA IMMUNE SYSTEM 04/16/14 S2 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.243 0.213 True 2ak4 E D NA NA abTCR 0 C peptide ebv peptide lpeplpqgqltay NA MH1 A B 71.108 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 10/11/05 Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N.A., Miles, J.J., Beddoe, T., Whisstock, J.C., Wilce, M.C., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Konstenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.278 0.246 True 2aq3 G NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.3 X-RAY DIFFRACTION 0.271 0.206 True 5eu6 E D NA NA abTCR 0 C peptide tyr-leu-glu-pro-gly-pro-val-thr-val NA MH1 A B 47.784 TRBV7 TRAV21 NA NA IMMUNE SYSTEM 03/02/16 HLA Class I antigen homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Rizkallah, P.J., Bianchi, V., Cole, D.K., Sewell, A.K. 2.02 X-RAY DIFFRACTION 0.222 0.181 True 4x6c H G NA NA abTCR 0 A Hapten (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide 42H CD1 A NA 81.061 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/28/15 CD1a ternary complex with lysophosphatidylcholine and BK6 TCR homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.236 0.176 True 7pbe J I NA NA abTCR 0 H peptide spike protein s1 NA MH1 F G 49.843 TRBV7 TRAV12 NA NA IMMUNE SYSTEM 04/27/22 Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Wall, A., Fuller, A. 3 X-RAY DIFFRACTION 0.296 0.228 True 4z7w F E NA NA abTCR 0 I | K | K peptide | carbohydrate | carbohydrate dq8-glia-alpha1 | ALPHA-D-MANNOSE | ALPHA-D-MANNOSE NA | MAN | MAN MH2 C D 45.882 TRBV6 TRAV8 NA NA IMMUNE SYSTEM 06/03/15 T316 complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Rossjohn, J., Reid, H.H., Koning, F. 2.89 X-RAY DIFFRACTION 0.247 0.228 True 6v18 E D NA NA abTCR 0 C peptide fibrinogen beta NA MH2 A B 23.340 TRBV4 TRAV6 NA NA IMMUNE SYSTEM 11/25/20 immune receptor complex mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lim, J.J., Rossjohn, J. 2.35 X-RAY DIFFRACTION 0.231 0.193 True 8eo8 E D NA NA abTCR 0 C peptide nucleoprotein np8 epitope NA MH1 A B 41.527 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.3 X-RAY DIFFRACTION 0.219 0.181 True 5wkh J I NA NA abTCR 0 H peptide gts3 peptide NA MH1 F G 39.564 TRBV11 TRAV30 NA NA IMMUNE SYSTEM 09/20/17 D30 TCR in complex with HLA-A*11:01-GTS3 homo sapiens homo sapiens dengue virus 3 homo sapiens homo sapiens Gras, S., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.246 0.177 True 6fr7 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.31 X-RAY DIFFRACTION 0.277 0.219 True 7t2b T S NA NA abTCR 0 R peptide pneumolysin-derived peptide NA MH2 P Q 36.809 TRBV6 TRAV17 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the 5F TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.250 0.216 True 3o8x D C NA NA abTCR 0 A Hapten (2S,3R)-3-HYDROXY-2-(TETRADECANOYLAMINO)OCTADECYL ALPHA-D-GALACTOPYRANOSIDURONIC ACID GSL CD1 A B 24.928 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 09/29/10 Recognition of Glycolipid Antigen by iNKT Cell TCR mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Li, Y. 2.74 X-RAY DIFFRACTION 0.253 0.195 True 7sg1 J I NA NA abTCR 0 H peptide dq2-glia-alpha1a peptide NA MH2 F G 35.221 TRBV29 TRAV4 NA NA IMMUNE SYSTEM 02/23/22 XPA5 TCR in complex with HLA-DQ2-alpha1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.258 0.217 True 3w0w E D NA NA abTCR 0 C peptide 10-mer peptide from protein nef NA MH1 A B nan TRBV27 TRAV12 NA NA IMMUNE SYSTEM 11/06/13 The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide in space group P212121 homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.603 X-RAY DIFFRACTION 0.250 0.186 True 5w1v T S NA NA abTCR 0 R peptide vmaprtlil peptide from cmv gpul40 NA MH1 P Q 59.853 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex homo sapiens homo sapiens human herpesvirus 5 strain ad169 homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.31 X-RAY DIFFRACTION 0.268 0.225 True 1sbb A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/01/99 T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB mus musculus Li, H., Mariuzza, R.A. 2.4 X-RAY DIFFRACTION 0.309 0.228 True 6avf B A NA NA abTCR 0 P peptide ala-pro-arg-gly-pro-his-gly-gly-ala-ala-ser-gly-leu NA MH1 H M 40.558 TRBV28 TRAV4 NA NA IMMUNE SYSTEM 02/28/18 Crystal structure of the KFJ5 TCR-NY-ESO-1-HLA-B*07:02 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gully, B.S., Gras, S., Rossjohn, J. 2.028 X-RAY DIFFRACTION 0.256 0.204 True 6fun B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.58 X-RAY DIFFRACTION 0.207 0.174 True 5nht B A NA NA abTCR 0 P peptide melanoma antigen recognized by t-cells 1 NA MH1 H L 34.791 TRBV19 TRAV12 NA NA IMMUNE SYSTEM 05/16/18 human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Exertier, C., Reiser, J.-B., Lantez, V., Chouquet, A., Bonneville, M., Saulquin, X., Housset, D. 3.2 X-RAY DIFFRACTION 0.299 0.213 True 6eh9 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.49 X-RAY DIFFRACTION 0.297 0.232 True 6ulr E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV4 NA NA IMMUNE SYSTEM 05/27/20 Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation homo sapiens homo sapiens Sun, P.D., Sim, M.J.W. 3.2 X-RAY DIFFRACTION 0.262 0.222 True 4grm B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/10/13 The crystal structure of the high affinity TCR A6 homo sapiens homo sapiens Borbulevych, O.Y., Scott, D.R., Baker, B.M. 2 X-RAY DIFFRACTION 0.295 0.234 True 3tpu N M NA NA abTCR 0 R peptide p5e8 peptide NA MH1 Q NA 43.032 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 p5E8/H2-Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 3.1 X-RAY DIFFRACTION 0.258 0.231 True 1hxm NA NA G H gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV9 TRDV2 IMMUNE SYSTEM 06/20/01 Crystal Structure of a Human Vgamma9/Vdelta2 T Cell Receptor homo sapiens homo sapiens Allison, T.J., Winter, C.C., Fournie, J.J., Bonneville, M., Garboczi, D.N. 3.12 X-RAY DIFFRACTION 0.266 0.219 True 7rrg E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV11 TRAV4 NA NA IMMUNE SYSTEM 03/23/22 Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide homo sapiens homo sapiens Ma, J., Baker, B.M. 2.12 X-RAY DIFFRACTION 0.221 0.193 True 2p5e E D NA NA abTCR 0 C peptide cancer/testis antigen 1b NA MH1 A B 66.648 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 09/25/07 Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal Binding Geometry homo sapiens homo sapiens homo sapiens homo sapiens Sami, M., Rizkallah, P.J., Dunn, S., Li, Y., Moysey, R., Vuidepot, A., Baston, E., Todorov, P., Molloy, P., Gao, F., Boulter, J.M., Jakobsen, B.K. 1.89 X-RAY DIFFRACTION 0.236 0.178 True 4p2o D C NA NA abTCR 0 P peptide 2a peptide NA MH2 A B 38.808 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 2B4 TCR in complex with 2A/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 2.603 X-RAY DIFFRACTION 0.245 0.189 True 7nme E D NA NA abTCR 0 C peptide gln-leu-pro-arg-leu-phe-pro-leu-leu NA MH1 A B 36.100 TRBV7 TRAV5 NA NA IMMUNE SYSTEM 09/07/22 Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Cole, D.K., Wall, A. 2.2 X-RAY DIFFRACTION 0.274 0.215 True 5jzi J I NA NA abTCR 0 H peptide klv peptide NA MH1 F G 31.848 TRBV25 TRAV38 NA NA Protein binding/Immune System 05/31/17 Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide homo sapiens homo sapiens hepatitis c virus homo sapiens homo sapiens Wang, Y., Piepenbrink, K.H., Baker, B.M. 2.5 X-RAY DIFFRACTION 0.232 0.196 True 8i5c O N NA NA abTCR 0 M peptide tcr alpha chain NA MH1 K L 48.320 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 True 3tpu D C NA NA abTCR 0 F peptide p5e8 peptide NA MH1 E NA 42.225 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 p5E8/H2-Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 3.1 X-RAY DIFFRACTION 0.258 0.231 True 4pjg H G NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 57.543 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-F3-C1 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.213 0.167 True 2z35 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV6 NA NA IMMUNE SYSTEM 10/09/07 Crystal structure of immune receptor mus musculus mus musculus Feng, D., Bond, C.J., Ely, L.K., Garcia, K.C. 2.2 X-RAY DIFFRACTION 0.285 0.263 True 7s8j B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV27 TRAV27 NA NA IMMUNE SYSTEM 11/02/22 PHOSPHOPEPTIDE-SPECIFIC LC13 TCR, ORTHORHOMBIC CRYSTAL FORM homo sapiens homo sapiens Patskovska, L., Patskovsky, Y., Nyovanie, S., Natarajan, A., Joshi, B., Morin, B., Brittsan, C., Huber, O., Gordon, S., Michelet, X., Schmitzberger, F., Stein, R., Findeis, M., Hurwitz, A., Van Dijk, M., Buell, J., Underwood, D., Krogsgaard, M. 1.92 X-RAY DIFFRACTION 0.213 0.168 True 4e41 E D NA NA abTCR 0 C peptide triosephosphate isomerase NA MH2 A B 44.902 TRBV5 TRAV22 NA NA IMMUNE SYSTEM 08/29/12 Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A. 2.6 X-RAY DIFFRACTION 0.264 0.197 True 6am5 E D NA NA abTCR 0 C peptide ser-met-leu-gly-ile-gly-ile-val-pro-val NA MH1 A B 33.258 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 08/08/18 Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide SMLGIGIVPV homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Riley, T.P., Baker, B.M. 2.394 X-RAY DIFFRACTION 0.244 0.201 True 1kb5 B A NA NA abTCR 0 L | H protein | protein antibody desire-1 | antibody desire-1 NA | NA NA NA NA nan TRBV1 TRAV14 NA NA COMPLEX (IMMUNOGLOBULIN/RECEPTOR) 04/08/98 MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX mus musculus mus musculus mus musculus | mus musculus Housset, D., Mazza, G., Gregoire, C., Piras, C., Malissen, B., Fontecilla-Camps, J.C. 2.5 X-RAY DIFFRACTION unknown 0.219 True 3e2h C B NA NA abTCR 0 Q peptide ql9 peptide NA MH1 A NA 46.409 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the m67 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 3.8 X-RAY DIFFRACTION 0.276 0.223 True 6c68 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV12 NA NA IMMUNE SYSTEM 01/30/19 MHC-independent t cell receptor A11 mus musculus mus musculus Lu, J., Van Laethem, F., Saba, I., Chu, J., Bhattacharya, A., Love, N.C., Tikhonova, A., Radaev, S., Sun, X., Ko, A., Arnon, T., Shifrut, E., Friedman, N., Weng, N., Singer, A., Sun, P.D. 2.59 X-RAY DIFFRACTION 0.258 0.202 True 4udu B A NA NA abTCR 0 C protein enterotoxin type e NA NA NA NA nan TRBV7 TRAV22 NA NA IMMUNE SYSTEM 06/24/15 Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor homo sapiens homo sapiens staphylococcus aureus Rodstrom, K.E.J., Regenthal, P., Lindkvist-Petersson, K. 2.5 X-RAY DIFFRACTION 0.255 0.246 True 6puj G B NA NA abTCR 0 A Hapten 6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione Q7S MR1 A H 61.517 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.92 X-RAY DIFFRACTION 0.194 0.163 True 2ak4 J I NA NA abTCR 0 H peptide ebv peptide lpeplpqgqltay NA MH1 F G 70.586 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 10/11/05 Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N.A., Miles, J.J., Beddoe, T., Whisstock, J.C., Wilce, M.C., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Konstenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.278 0.246 True 3mv8 E D NA NA abTCR 0 C peptide hpvg peptide from epstein-barr nuclear antigen 1 NA MH1 A B 41.600 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Chen, Z., Miles, J.J., Liu, Y.C., Bell, M.J., Sullivan, L.C., Kjer-Nielsen, L., Brennan, R.M., Burrows, J.M., Neller, M.A., Khanna, R., Purcell, A.W., Brooks, A.G., McCluskey, J., Rossjohn, J., Burrows, S.R. 2.1 X-RAY DIFFRACTION 0.276 0.229 True 6puc H G NA NA abTCR 0 A Hapten 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol Q87 MR1 A B 61.531 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.85 X-RAY DIFFRACTION 0.178 0.159 True 6bj3 H NA NA NA NA 0 D | C protein | peptide tcr 55 alpha chain | hiv pol b35 peptide NA | NA MH1 A B nan TRBV6 NA NA NA IMMUNE SYSTEM 07/25/18 TCR55 in complex with HIV(Pol448-456)/HLA-B35 homo sapiens homo sapiens | human immunodeficiency virus 1 homo sapiens homo sapiens Jude, K.M., Sibener, L.V., Garcia, K.C. 1.898 X-RAY DIFFRACTION 0.216 0.188 True 5wjo D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV26 NA NA IMMUNE SYSTEM 10/25/17 Crystal structure of the unliganded PG90 TCR homo sapiens homo sapiens Shahine, A., Gras, S., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.230 0.208 True 3kpr E D NA NA abTCR 0 C peptide eeylkawtf, mimotope peptide NA MH1 A B 41.623 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 12/22/09 Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope homo sapiens homo sapiens homo sapiens homo sapiens Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J. 2.6 X-RAY DIFFRACTION 0.279 0.219 True 6fr9 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.62 X-RAY DIFFRACTION 0.211 0.179 True 5hyj E D NA NA abTCR 0 C peptide ala-gln-trp-gly-pro-asp-pro-ala-ala-ala NA MH1 A B 43.272 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 3.06 X-RAY DIFFRACTION 0.294 0.212 True 5ks9 H G NA NA abTCR 0 J peptide dq8-glia-alpha1 peptide NA MH2 A B 38.991 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 09/21/16 Bel502-DQ8-glia-alpha1 complex homo sapiens homo sapiens triticum aestivum homo sapiens triticum aestivum, homo sapiens Petersen, J., Rossjohn, J., Reid, H.H. 2.55 X-RAY DIFFRACTION 0.224 0.199 True 7t2d O N NA NA abTCR 0 M peptide pneumolysin-derived peptide NA MH2 K L 58.195 TRBV7 TRAV19 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the B1 TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.4 X-RAY DIFFRACTION 0.271 0.236 True 1kj2 E D NA NA abTCR 0 Q peptide naturally processed octapeptide pkb1 NA MH1 I M 30.449 TRBV1 TRAV14 NA NA IMMUNE SYSTEM 03/27/02 Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex mus musculus mus musculus mus musculus mus musculus Reiser, J.-B., Gregoire, C., Darnault, C., Mosser, T., Guimezanes, A., Schmitt-Verhulst, A.-M., Fontecilla-Camps, J.C., Mazza, G., Malissen, B., Housset, D. 2.71 X-RAY DIFFRACTION 0.278 0.220 True 6mja D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-1-({4-O-[(4-methylphenyl)methyl]-alpha-D-galactopyranosyl}oxy)octadecan-2-yl]hexacosanamide JTJ CD1 A B 25.780 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxo (JJ294) /iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2.35 X-RAY DIFFRACTION 0.237 0.196 True 6r0e E D NA NA abTCR 0 C peptide unknown NA MH2 A B 47.987 TRBV24 TRAV8 NA NA IMMUNE SYSTEM 01/08/09 Structure of F11TCR in complex with DR1 MHC Class II presenting PKYVKQNTLKLAT Rizkallah, P.J., Greenshields-Watson, A.L. 1.91 X-RAY DIFFRACTION 0.233 0.206 False 6vth E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 06/17/20 p53-specific T cell receptor homo sapiens homo sapiens Wu, D., Gallagher, D.T., Gowthaman, R., Pierce, B.G., Mariuzza, R.A. 2.36 X-RAY DIFFRACTION 0.264 0.212 True 6rpb E D NA NA abTCR 0 C peptide heteroclitic ny-eso-1 157-165 peptide NA MH1 A B 70.011 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 2.5 X-RAY DIFFRACTION 0.273 0.249 True 7t2b J I NA NA abTCR 0 H peptide pneumolysin-derived peptide NA MH2 F G 37.521 TRBV6 TRAV17 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the 5F TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.250 0.216 True 4x6b B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/28/15 BK6 TCR apo structure homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.229 0.188 True 6uon J I NA NA abTCR 0 C peptide gly-ala-asp-gly-val-gly-lys-ser-ala-leu NA MH1 A B 63.855 TRBV10 TRAV12 NA NA IMMUNE SYSTEM 05/27/20 Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Sun, P.D., Sim, M.J.W. 3.5 X-RAY DIFFRACTION 0.294 0.252 True 6ovn B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV4 TRAV17 NA NA IMMUNE SYSTEM 11/20/19 Crystal structure of the unliganded Clone 2 TCR homo sapiens homo sapiens Shahine, A., Rossjohn, J. 1.77 X-RAY DIFFRACTION 0.201 0.170 True 1zgl P M NA NA abTCR 0 C peptide myelin basic protein NA MH2 A B 39.764 TRBV5 TRAV9 NA NA IMMUNE SYSTEM 10/18/05 Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Li, Y., Huang, Y., Lue, J., Quandt, J.A., Martin, R., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.329 0.280 True 3pqy T S NA NA abTCR 0 R peptide 10-mer peptide from rna-directed rna polymerase NA MH1 P Q 50.047 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 05/18/11 Crystal Structure of 6218 TCR in complex with the H2Db-PA224 mus musculus, homo sapiens mus musculus, homo sapiens synthetic construct mus musculus mus musculus Gras, S., Guillonneau, C., Turner, S.J., Rossjohn, J. 3.192 X-RAY DIFFRACTION 0.316 0.246 True 4y19 E D NA NA abTCR 0 C peptide insulin NA MH2 A B 42.129 TRBV6 TRAV29 NA NA IMMUNE SYSTEM 09/23/15 immune complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Beringer, D.X., Petersen, J., Reid, H.H., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.196 0.160 True 6avg D C NA NA abTCR 0 P peptide ala-pro-arg-gly-pro-his-gly-gly-ala-ala-ser-gly-leu NA MH1 G H 38.383 TRBV9 TRAV4 NA NA IMMUNE SYSTEM 02/28/18 Crystal structure of the KFJ37 TCR-NY-ESO-1-HLA-B*07:02 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gully, B.S., Gras, S., Rossjohn, J. 2.6 X-RAY DIFFRACTION 0.248 0.193 True 6v15 E D NA NA abTCR 0 C peptide fibrinogen beta 72,74cit69-81 NA MH2 A B 25.392 TRBV4 TRAV6 NA NA IMMUNE SYSTEM 11/25/20 immune receptor complex mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lim, J.J., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.233 0.197 True 1ktk E NA NA NA NA 0 A protein exotoxin type c NA NA NA NA nan TRBV20 NA NA NA IMMUNE SYSTEM 06/07/02 Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1) homo sapiens streptococcus pyogenes Sundberg, E.J., Li, H., Llera, A.S., McCormick, J.K., Tormo, J., Karjalainen, K., Schlievert, P.M., Mariuzza, R.A. 3 X-RAY DIFFRACTION 0.334 0.326 True 4lhu NA NA D G gdTCR 0 A Hapten (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide JLS CD1 A B 60.020 NA NA TRGV5 TRDV1 IMMUNE SYSTEM 10/02/13 Crystal Structure of 9C2 TCR bound to CD1d homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Uldrich, A.P., Le Nours, J., Pellicci, D.G., Gras, S., Rossjohn, J., Godfrey, D.I. 2.87 X-RAY DIFFRACTION 0.243 0.206 True 4z7u H G NA NA abTCR 0 J peptide deamidated dq8-glia-alpha1 peptide NA MH2 A B 37.230 TRBV9 TRAV26 NA NA IMMUNE SYSTEM 06/03/15 S13 complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Rossjohn, J., Reid, H.H., Koning, F. 2.7 X-RAY DIFFRACTION 0.220 0.178 True 7rm4 I J NA NA abTCR 0 H peptide cellular tumor antigen p53 peptide NA MH1 F G 35.095 TRBV11 TRAV6 NA NA IMMUNE SYSTEM 02/09/22 Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 3.33 X-RAY DIFFRACTION 0.295 0.237 True 4qok E D NA NA abTCR 0 C peptide melanoma antigen recognized by t-cells 1 marker peptide NA MH1 A B 47.655 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 12/17/14 Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K. 3 X-RAY DIFFRACTION 0.262 0.203 True 3pwp E D NA NA abTCR 0 C peptide hud peptide NA MH1 A B 36.633 TRBV6 TRAV12 NA NA PROTEIN BINDING 03/09/11 The complex between TCR A6 and human Class I MHC HLA-A2 with the bound HuD peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.69 X-RAY DIFFRACTION 0.259 0.198 True 5w1v O N NA NA abTCR 0 M peptide vmaprtlil peptide from cmv gpul40 NA MH1 K L 68.607 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex homo sapiens homo sapiens human herpesvirus 5 strain ad169 homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.31 X-RAY DIFFRACTION 0.268 0.225 True 3owe E NA NA NA NA 0 J protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 7n6e H G NA NA abTCR 0 F peptide spike protein s1 NA MH1 D E 54.175 TRBV19 TRAV12 NA NA IMMUNE SYSTEM/VIRAL PROTEIN 07/28/21 TCR peptide HLA-A2 complex homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Chaurasia, P., Rossjohn, J., Petersen, J. 3.2 X-RAY DIFFRACTION 0.294 0.239 True 6at6 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV4 NA NA IMMUNE SYSTEM 02/28/18 Crystal structure of the KFJ5 TCR homo sapiens homo sapiens Gully, B.S., Rossjohn, J. 1.417 X-RAY DIFFRACTION 0.218 0.198 True 8wul F E NA NA abTCR 0 Q peptide kras-g12v nonamer peptide NA MH1 O P 63.523 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 05/01/24 Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Zhang, M.Y., Luo, L.J., Xu, W., Guan, F.H., Wang, X.Y., Zhu, P., Zhang, J.H., Zhou, X.Y., Wang, F., Ye, S. 2.36 X-RAY DIFFRACTION 0.235 0.190 True 3tyf B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 04/25/12 Crystal structure of a CD1d-lysophosphatidylcholine reactive iNKT TCR escherichia coli escherichia coli Lopez-Sagaseta, J., Adams, E.J. 2.806 X-RAY DIFFRACTION 0.272 0.217 True 4pje F E NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 60.349 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-B10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 1.95 X-RAY DIFFRACTION 0.197 0.171 True 1zgl T S NA NA abTCR 0 I peptide myelin basic protein NA MH2 G H 40.608 TRBV5 TRAV9 NA NA IMMUNE SYSTEM 10/18/05 Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Li, Y., Huang, Y., Lue, J., Quandt, J.A., Martin, R., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.329 0.280 True 3dxa E D NA NA abTCR 0 C peptide ebv decapeptide epitope NA MH1 A B 58.057 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of the DM1 TCR in complex with HLA-B*4405 and decamer EBV antigen homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Macdonald, W.A., Gras, S., Rossjohn, J. 3.5 X-RAY DIFFRACTION 0.330 0.286 True 6pug E D NA NA abTCR 0 C Hapten 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione OZD MR1 C F 59.030 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-2`OH-Ethyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.8 X-RAY DIFFRACTION 0.194 0.160 True 8i5c T S NA NA abTCR 0 R peptide tcr alpha chain NA MH1 P Q 47.881 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 True 6rp9 J I NA NA abTCR 0 H peptide cancer/testis antigen 1 NA MH1 F G 64.203 TRBV7 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 3.12 X-RAY DIFFRACTION 0.250 0.223 True 4mji J I NA NA abTCR 0 H peptide hiv reverse transcriptase peptide marker NA MH1 F G 43.980 TRBV7 TRAV17 NA NA IMMUNE SYSTEM 05/28/14 T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01 homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Motozono, C., Takiguchi, M. 2.99 X-RAY DIFFRACTION 0.304 0.242 True 3qh3 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/04/12 The crystal structure of TCR A6 homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.19 X-RAY DIFFRACTION 0.274 0.202 True 6v19 E D NA NA abTCR 0 C peptide fibrinogen beta 72,74cit69-81 NA MH2 A B 23.818 TRBV4 TRAV6 NA NA IMMUNE SYSTEM 11/25/20 immune receptor complex mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lim, J.J., Rossjohn, J. 2.6 X-RAY DIFFRACTION 0.224 0.202 True 6uk2 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV38 NA NA IMMUNE SYSTEM 08/19/20 Complex of T cell Receptor with HHAT Wild Type Peptide KQWLVWLLL Presented by HLA-A206 homo sapiens homo sapiens Devlin, J.R., Baker, B.M. 3.13881 X-RAY DIFFRACTION 0.260 0.229 True 2wbj D C NA NA abTCR 0 A carbohydrate N-ACETYL-D-GLUCOSAMINE NAG MH2 A B 79.376 TRBV20 TRAV17 NA NA IMMUNE SYSTEM 04/07/09 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Harkiolaki, M., Holmes, S.L., Svendsen, P., Gregersen, J.W., Jensen, L.T., McMahon, R., Friese, M.A., van Boxel, G., Etzensperger, R., Tzartos, J.S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E.D., Palace, J., Esiri, M.M., van der Merwe, P.A., Jones, E.Y., Fugger, L. 3 X-RAY DIFFRACTION 0.288 0.247 True 7rdv D C NA NA abTCR 0 H peptide aggrecan core peptide NA GA A NA nan TRBV13 TRAV5 NA NA IMMUNE SYSTEM 07/27/22 TFH TCR bound to MHC Class II IAd presenting aggrecan epitope mus musculus mus musculus homo sapiens mus musculus Lim, J.J., Rossjohn, J., Reid, H. 2.90007 X-RAY DIFFRACTION 0.265 0.237 True 3e3q e d NA NA abTCR 0 f peptide unknown NA MH1 c NA 42.509 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 False 6rp9 L K NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 3.12 X-RAY DIFFRACTION 0.250 0.223 True 4ms8 D C NA NA abTCR 0 B peptide pcpb9 NA MH1 A NA 66.268 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 09/24/14 42F3 TCR pCPB9/H-2Ld Complex mus musculus mus musculus mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 1.922 X-RAY DIFFRACTION 0.219 0.181 True 6vmx E D NA NA abTCR 0 C peptide epstein-barr nuclear antigen 3 NA MH1 A B 55.610 TRBV4 TRAV24 NA NA IMMUNE SYSTEM 07/29/20 Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope homo sapiens homo sapiens epstein-barr virus (strain b95-8) homo sapiens homo sapiens Farenc, C., Rossjohn, J., Gras, S. 3.1 X-RAY DIFFRACTION 0.242 0.221 True 5til H G NA NA abTCR 0 C peptide pre-glycoprotein polyprotein gp complex NA MH1 A B 45.162 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 11/01/17 Murine class I major histocompatibility complex H-2 Db in complex with LCMV-derived GP33 altered peptide V3P and T-cell receptor P14 mus musculus mus musculus lymphocytic choriomeningitis mammarenavirus mus musculus mus musculus Achour, A., Sandalova, T., Allerbring, E.B. 2.83 X-RAY DIFFRACTION 0.275 0.219 True 7fjd n m NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/27/22 Cryo-EM structure of a membrane protein(WT) homo sapiens homo sapiens Chen, Y., Zhu, Y., Gao, W., Zhang, A., Guo, C., Huang, Z. 3.2 ELECTRON MICROSCOPY NA NA False 4h1l J I NA NA abTCR 0 C peptide mimotope peptide NA MH2 A B 55.243 TRBV19 TRAV8 NA NA IMMUNE SYSTEM 11/14/12 TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy escherichia coli escherichia coli escherichia coli homo sapiens homo sapiens Kappler, J.W., Yin, L., Dai, S., Marrack, P. 3.3 X-RAY DIFFRACTION 0.285 0.263 True 3qi9 D C NA NA abTCR 0 A Hapten 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE PII CD1 A B 23.902 TRBV19 TRAV11 NA NA IMMUNE SYSTEM 02/15/12 Crystal structure of mouse CD1d-alpha-phosphotidylinositol with mouse Valpha14-Vbeta6 2A3-D NKT TCR mus musculus mus musculus mus musculus mus musculus mus musculus Clarke, A.J., Rossjohn, J. 2.3 X-RAY DIFFRACTION 0.275 0.247 True 3r8b L NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 2f53 E D NA NA abTCR 0 C peptide cancer/testis antigen 1b NA MH1 A B 66.123 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 04/25/06 Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Jakobsen, B.K., Dunn, S.M., Sami, M. 2.1 X-RAY DIFFRACTION 0.231 0.166 True 3qdj E D NA NA abTCR 0 C peptide mart-1(27-35) peptide NA MH1 A B 33.874 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/06/11 The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.3 X-RAY DIFFRACTION 0.299 0.240 True 6xcp E D NA NA abTCR 0 NA NA NA NA MH2 A C 34.263 TRBV5 TRAV26 NA NA IMMUNE SYSTEM 07/14/21 Immune receptor complex homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Faridi, P., Lim, J.J., Ting, T.Y., Onwukwe, G., Bhattacharjee, P., Jones, M.C., Tresoldi, E., Cameron, J.F., La-Gruta, L.N., Purcell, W.A., Mannering, I.S., Rossjohn, J., Reid, H.H. 3.3 X-RAY DIFFRACTION 0.268 0.234 True 4x6d H G NA NA abTCR 0 I carbohydrate N-ACETYL-D-GLUCOSAMINE NAG CD1 A B 81.373 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/28/15 CD1a ternary complex with endogenous lipids and BK6 TCR homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.98 X-RAY DIFFRACTION 0.229 0.177 True 6puh E D NA NA abTCR 0 C Hapten 6-methyl-5-[(1E)-3-oxobut-1-en-1-yl]pyrimidine-2,4(1H,3H)-dione OYG MR1 C F 59.462 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-Ribityl-less homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.88 X-RAY DIFFRACTION 0.195 0.160 True 5l2k E D NA NA abTCR 0 E Hapten 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose 70E CD1 A B 70.125 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 11/16/16 Crystal structure of GEM42 TCR-CD1b-GMM complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Shahine, A., Le Nours, J., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.239 0.218 True 5d7l H G NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 43.532 TRBV28 TRAV36 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-5-OP-RU in complex with human MAV36 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 3.4 X-RAY DIFFRACTION 0.337 0.280 True 7pbe E D NA NA abTCR 0 C peptide spike protein s1 NA MH1 A B 52.285 TRBV7 TRAV12 NA NA IMMUNE SYSTEM 04/27/22 Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Wall, A., Fuller, A. 3 X-RAY DIFFRACTION 0.296 0.228 True 6bj2 E D NA NA abTCR 0 C peptide hiv pol b35 peptide NA MH1 A B 41.850 TRBV5 TRAV19 NA NA IMMUNE SYSTEM 07/25/18 TCR589 in complex with HIV(Pol448-456)/HLA-B35 homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Jude, K.M., Sibener, L.V., Garcia, K.C. 3.35 X-RAY DIFFRACTION 0.276 0.245 True 3pqy E D NA NA abTCR 0 C peptide 10-mer peptide from rna-directed rna polymerase NA MH1 A B 50.550 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 05/18/11 Crystal Structure of 6218 TCR in complex with the H2Db-PA224 mus musculus, homo sapiens mus musculus, homo sapiens synthetic construct mus musculus mus musculus Gras, S., Guillonneau, C., Turner, S.J., Rossjohn, J. 3.192 X-RAY DIFFRACTION 0.316 0.246 True 6mj4 D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-1-{[4-O-(prop-2-en-1-yl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide JTG CD1 A B 26.229 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of MCD1D/INKTCR TERNARY COMPLEX bound to glycolipid (XXW) mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2 X-RAY DIFFRACTION 0.214 0.185 True 6cw9 D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxy-16-phenylhexadecan-2-yl]octanamide 7LM CD1 A B 26.433 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/03/19 Structure of alpha-GC[8,16P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2 X-RAY DIFFRACTION 0.221 0.190 True 6puh G B NA NA abTCR 0 NA NA NA NA MR1 A H 61.409 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-Ribityl-less homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.88 X-RAY DIFFRACTION 0.195 0.160 True 6dfv D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV5 NA NA IMMUNE SYSTEM 04/17/19 Mouse diabetogenic TCR 8F10 mus musculus mus musculus Wang, Y., Dai, S. 1.71 X-RAY DIFFRACTION 0.231 0.171 True 3qdm E D NA NA abTCR 0 C peptide mart-1(27-35) peptide NA MH1 A B 30.930 TRBV10 TRAV35 NA NA IMMUNE SYSTEM 07/06/11 The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) decameric peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.8 X-RAY DIFFRACTION 0.284 0.211 True 8d5p D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV1 TRAV6 NA NA IMMUNE SYSTEM 09/14/22 Mouse TCR TG6 mus musculus mus musculus Wang, Y., Dai, S. 2.75 X-RAY DIFFRACTION 0.301 0.224 True 7rtr E D NA NA abTCR 0 C peptide spike protein s1 NA MH1 A B 42.980 TRBV7 TRAV12 NA NA IMMUNE SYSTEM 10/13/21 YLQ-SG3 TCR in complex with SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01 homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Szeto, C., Gras, S. 2.6 X-RAY DIFFRACTION 0.235 0.191 True 8en8 E D NA NA abTCR 0 C peptide nucleoprotein np4 epitope NA MH1 A B 41.971 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP4 epitope from 1972 influenza strain homo sapiens homo sapiens influenza a virus (strain a/memphis/101/1972h3n2) homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.70001 X-RAY DIFFRACTION 0.249 0.207 True 6pvd E D NA NA abTCR 0 C Hapten methyl N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alaninate N18 MR1 C F 59.210 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/01/20 Structure of human MAIT A-F7 TCR in complex with human MR1-NV18.1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 2.14 X-RAY DIFFRACTION 0.198 0.168 True 1l0x C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 04/03/02 TCR beta chain complexed with streptococcal superantigen SpeA mus musculus Li, H., Sundberg, E.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.278 0.232 True 4nqd H G NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 58.772 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TCR-MR1 ternary complex and non-covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.227 0.181 True 6mng B A NA NA abTCR 0 NA NA NA NA MH2 C D 45.946 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/03/19 4738 TCR bound to IAb Padi4 mus musculus mus musculus mus musculus mus musculus Blevins, S.J., Stadinski, B.D., Huseby, E.S. 2.662 X-RAY DIFFRACTION 0.269 0.230 True 2xna B A NA NA abTCR 0 C protein enterotoxin h NA NA NA NA nan TRBV19 TRAV27 NA NA IMMUNE SYSTEM 11/24/10 Crystal structure of the complex between human T cell receptor and staphylococcal enterotoxin homo sapiens homo sapiens staphylococcus aureus Saline, M., Rodstrom, K.E.J., Fischer, G., Orekhov, V.Y., Karlsson, B.G., Lindkvist-Petersson, K. 2.1 X-RAY DIFFRACTION 0.26137 0.22256 True 6xco E D NA NA abTCR 0 NA NA NA NA MH2 A B 34.911 TRBV5 TRAV20 NA NA IMMUNE SYSTEM 07/14/21 Immune receptor complex homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Faridi, P., Lim, J.J., Ting, T.Y., Onwukwe, G., Bhattacharjee, P., Jones, M.C., Tresoldi, E., Cameron, J.F., La-Gruta, L.N., Purcell, W.A., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.9 X-RAY DIFFRACTION 0.247 0.207 True 1ymm E D NA NA abTCR 0 C peptide mbp peptide NA MH2 A B 82.519 TRBV20 TRAV17 NA NA IMMUNE SYSTEM 05/03/05 TCR/HLA-DR2b/MBP-peptide complex homo sapiens homo sapiens homo sapiens homo sapiens Hahn, M., Nicholson, M.J., Pyrdol, J., Wucherpfennig, K.W. 3.5 X-RAY DIFFRACTION 0.318 0.274 True 2ial B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 1.92 X-RAY DIFFRACTION 0.265 0.208 True 4c56 H G NA NA abTCR 0 L | I peptide | protein hemagglutinin | enterotoxin b NA | NA MH2 J K 63.696 TRBV19 TRAV22 NA NA IMMUNE SYSTEM/TOXIN 07/23/14 X-ray structure of the complex between staphylococcal enterotoxin B, T cell receptor and major histocompatibility complex class II homo sapiens homo sapiens influenza a virus | staphylococcus aureus homo sapiens homo sapiens Rodstrom, K.E.J., Elbing, K., Lindkvist-Petersson, K. 2.9 X-RAY DIFFRACTION 0.251 0.233 True 8gop B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV38 NA NA IMMUNE SYSTEM 03/01/23 SARS-CoV-2 specific private TCR RLQ7 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.286 0.231 True 5c07 E D NA NA abTCR 0 C peptide marker peptide NA MH1 A B 43.735 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.11 X-RAY DIFFRACTION 0.237 0.191 True 5d7i H G NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 58.946 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Woolley, R.E., Rossjohn, J. 2 X-RAY DIFFRACTION 0.220 0.178 True 3vxu E D NA NA abTCR 0 C peptide 10-mer peptide from protein nef NA MH1 A B nan TRBV27 TRAV12 NA NA IMMUNE SYSTEM 10/23/13 The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.7 X-RAY DIFFRACTION 0.323 0.272 True 5iw1 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV14 NA NA IMMUNE SYSTEM 03/29/17 Crystal Structure of B4.2.3 T-Cell Receptor mus musculus mus musculus Natarajan, K., Jiang, J., Margulies, D. 3.001 X-RAY DIFFRACTION 0.268 0.240 True 4qrr E NA NA NA NA 0 D | P protein | peptide clone12 tcr beta chain | ips peptide from cmv, ipsinvhhy NA | NA MH1 A B nan TRBV5 NA NA NA IMMUNE SYSTEM 12/10/14 Crystal Structure of HLA B*3501-IPS in complex with a Delta-Beta TCR, clone 12 TCR homo sapiens homo sapiens | human herpesvirus 5 homo sapiens homo sapiens Gras, S., Chabrol, E., Rossjohn, J. 3 X-RAY DIFFRACTION 0.258 0.210 True 3rev B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV3 NA NA IMMUNE SYSTEM 01/18/12 Crystal structure of human alloreactive tcr nb20 homo sapiens homo sapiens Wood, A., Mohammed, F., Salim, M., Tranter, A., Rickinson, A.B., Moss, P.A.H., Stauss, H.J., Steven, N.M., Willcox, B.E. 2.2 X-RAY DIFFRACTION 0.266 0.232 True 3tpu B A NA NA abTCR 0 J peptide p5e8 peptide NA MH1 I NA 42.339 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 p5E8/H2-Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 3.1 X-RAY DIFFRACTION 0.258 0.231 True 8eo8 J I NA NA abTCR 0 H peptide nucleoprotein np8 epitope NA MH1 F G 42.291 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.3 X-RAY DIFFRACTION 0.219 0.181 True 6vqo E D NA NA abTCR 0 P peptide peptide from p53 tumor suppressor NA MH1 A B 30.035 TRBV27 TRAV12 NA NA IMMUNE SYSTEM 06/17/20 T cell receptor-p53-HLA-A2 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Gallagher, D.T., Pierce, B.G., Mariuzza, R.A. 3 X-RAY DIFFRACTION 0.211 0.162 True 1j8h E D NA NA abTCR 0 C peptide hemagglutinin ha1 peptide chain NA MH2 A B 48.329 TRBV28 TRAV8 NA NA IMMUNE SYSTEM 03/13/02 Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide, and MHC Class II Molecule, HLA-DR4 homo sapiens homo sapiens influenzavirus a homo sapiens homo sapiens Hennecke, J., Wiley, D.C. 2.4 X-RAY DIFFRACTION 0.246 0.211 True 4nqe H G NA NA abTCR 0 A Hapten 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxoethylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol 2L4 MR1 A B 59.343 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TCR-MR1 ternary complex bound to 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.222 0.182 True 4g8e B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV1 NA NA IMMUNE SYSTEM 05/08/13 Crystal Structure of clone18 TCR homo sapiens homo sapiens Gras, S., Bhati, M., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.294 0.241 True 8enh J I NA NA abTCR 0 H peptide nucleoprotein np7 epitope NA MH1 F G 41.668 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain homo sapiens homo sapiens influenza a virus (strain a/2002/h3n2) homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.50003 X-RAY DIFFRACTION 0.230 0.191 True 2p5w E D NA NA abTCR 0 C peptide cancer/testis antigen 1b NA MH1 A B 65.992 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 09/25/07 Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry homo sapiens homo sapiens homo sapiens homo sapiens Sami, M., Rizkallah, P.J., Dunn, S., Li, Y., Moysey, R., Vuidepot, A., Baston, E., Todorov, P., Molloy, P., Gao, F., Boulter, J.M., Jakobsen, B.K. 2.2 X-RAY DIFFRACTION 0.245 0.165 True 4ww2 B A NA NA abTCR 0 C Hapten (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide JLS CD1 C F 54.124 TRBV7 TRAV21 NA NA IMMUNE SYSTEM 02/03/16 Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Le Nours, J., Praveena, T., Pellicci, D., Gherardin, N.A., Lim, R.T., Besra, G., Keshipeddy, S., Richardson, S.K., Howell, A.R., Gras, S., Godfrey, D.I., Rossjohn, J., Uldrich, A.P. 2.48 X-RAY DIFFRACTION 0.244 0.196 True 8vd0 E D NA NA abTCR 0 NA NA NA NA MH2 A C 39.299 TRBV5 TRAV26 NA NA IMMUNE SYSTEM 08/07/24 Human TCR ET650-4 in complex with DQ8-InsC8-15-IAPP2 homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Lim, J.J., Loh, T.Y., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.4 X-RAY DIFFRACTION 0.220 0.188 True 3utt E D NA NA abTCR 0 C peptide insulin NA MH1 A B 47.226 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 01/25/12 1E6-A*0201-ALWGPDPAAA Complex, Triclinic homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M., Rossjohn, J., Gras, S. 2.6 X-RAY DIFFRACTION 0.274 0.195 True 6pvc F E NA NA abTCR 0 C Hapten N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alanine P1J MR1 C D 58.161 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/01/20 Structure of human MAIT A-F7 TCR in complex with human MR1-DB28 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.96 X-RAY DIFFRACTION 0.212 0.169 True 7q99 E D NA NA abTCR 0 C peptide asn-leu-ser-ala-leu-gly-ile-phe-ser-thr NA MH1 A B 46.371 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 02/22/23 MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Wall, A., Fuller, A. 2.55 X-RAY DIFFRACTION 0.272 0.218 True 6mkd B A NA NA abTCR 0 NA NA NA NA MH2 C D 41.269 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/03/19 4699 TCR bound to I-Ab Padi4 mus musculus mus musculus mus musculus mus musculus Stadinski, B.D., Blevins, S.J., Huseby, E.S. 3.2 X-RAY DIFFRACTION 0.278 0.233 True 6w9u E D NA NA abTCR 0 C Hapten 1-[[6-(1-$l^{1}-oxidanylethyl)-4-$l^{3}-oxidanylidene-2,3,6,8~{a}-tetrahydropteridin-2-yl]-$l^{2}-azanyl]ethanone TKG MR1 C F 58.694 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 08/05/20 Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H-Ac-6-FP homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.89 X-RAY DIFFRACTION 0.197 0.162 True 6zkz E D NA NA abTCR 0 C peptide enoyl-[acyl-carrier-protein] reductase [nadh] NA MH1 A B 59.567 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 01/26/22 Crystal structure of InhA:01 TCR in complex with HLA-E (F116C) bound to InhA (53-61 H4C) homo sapiens homo sapiens mycobacterium tuberculosis h37rv homo sapiens homo sapiens Srikannathasan, V., Karuppiah, V., Robinson, R.A. 2.3 X-RAY DIFFRACTION 0.267 0.224 True 3arg D C NA NA abTCR 0 A Hapten (11E,14E)-N-[(2S,3S,4R)-1-(ALPHA-D-GLUCOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]ICOSA-11,14-DIENAMIDE DB6 CD1 A B 24.646 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 03/30/11 Ternary crystal structure of the mouse NKT TCR-CD1d-alpha-glucosylceramide(C20:2) mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wun, K.S., Rossjohn, J. 3 X-RAY DIFFRACTION 0.300 0.232 True 7amp B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 04/20/22 Crystal structure of the complex of HuJovi-1 Fab with the human A6 T-cell receptor TRBC1 homo sapiens homo sapiens Ferrari, M., Bulek, A., Bughda, R., Jha, R., Welin, M., Logan, D.T., Sewell, A., Onuoha, S., Pule, M. 2.64 X-RAY DIFFRACTION 0.289 0.237 True 4gg6 F E NA NA abTCR 0 I peptide peptide from alpha/beta-gliadin mm1 NA MH2 C D 41.923 TRBV9 TRAV26 NA NA IMMUNE SYSTEM 10/24/12 Protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Broughton, S.E., Theodossis, A., Petersen, J., Reid, H.H., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.285 0.246 True 3rug H G NA NA abTCR 0 C Hapten (11E,14E)-N-[(2S,3S,4R)-1-(ALPHA-D-GLUCOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]ICOSA-11,14-DIENAMIDE DB6 CD1 C D 27.340 TRBV13 TRAV13 NA NA IMMUNE SYSTEM 08/03/11 Crystal structure of Valpha10-Vbeta8.1 NKT TCR in complex with CD1d-alphaglucosylceramide (C20:2) mus musculus mus musculus mus musculus mus musculus mus musculus Patel, O., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.254 0.210 True 6avg E B NA NA abTCR 0 Q peptide ala-pro-arg-gly-pro-his-gly-gly-ala-ala-ser-gly-leu NA MH1 F A 38.304 TRBV9 TRAV4 NA NA IMMUNE SYSTEM 02/28/18 Crystal structure of the KFJ37 TCR-NY-ESO-1-HLA-B*07:02 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gully, B.S., Gras, S., Rossjohn, J. 2.6 X-RAY DIFFRACTION 0.248 0.193 True 4qrp L K NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV11 TRAV9 NA NA IMMUNE SYSTEM 11/12/14 Crystal Structure of HLA B*0801 in complex with HSKKKCDEL and DD31 TCR homo sapiens homo sapiens Gras, S., Berry, R., Lucet, I.S., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.248 0.207 True 3byy A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN 05/12/09 Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex mus musculus Cho, S., Eric, J.S. 2.2 X-RAY DIFFRACTION 0.233 0.190 True 4pj7 H G NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 59.233 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT TRBV6-4 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.219 0.171 True 6p64 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV38 NA NA IMMUNE SYSTEM 06/03/20 Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206 homo sapiens homo sapiens Devlin, J.R., Baker, B.M. 3.05 X-RAY DIFFRACTION 0.219 0.194 True 6tmo E D NA NA abTCR 0 C peptide eaagigiltv NA MH1 A B 43.378 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 10/07/20 Structure determination of an enhanced affinity TCR, a24b17, in complex with HLA-A*02:01 presenting a MART-1 peptide, EAAGIGILTV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.1 X-RAY DIFFRACTION 0.209 0.173 True 6pum H G NA NA abTCR 0 A Hapten 1,2-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol Q84 MR1 A B 61.576 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-2'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.96 X-RAY DIFFRACTION 0.190 0.154 True 8i5c s r NA NA abTCR 0 q peptide unknown NA MH1 o p 47.696 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 False 4elm H G NA NA abTCR 0 A Hapten (2S,3R,4E)-2-AMINO-3-HYDROXYOCTADEC-4-EN-1-YL 3-O-SULFO-BETA-D-GALACTOPYRANOSIDE SGF CD1 A B 72.197 TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Crystal structure of the mouse CD1d-lysosulfatide-Hy19.3 TCR complex mus musculus mus musculus mus musculus mus musculus mus musculus Girardi, E., Maricic, I., Wang, J., Mac, T.T., Iyer, P., Kumar, V., Zajonc, D.M. 3.48 X-RAY DIFFRACTION 0.265 0.209 True 7pdx B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 Crystal structure of parent MAGE-A10 TCR (728) Simister, P.C., Border, E.C., Vieira, J.F., Pumphrey, N.J. 2.27 X-RAY DIFFRACTION 0.252 0.192 False 3qiu D C NA NA abTCR 0 E peptide mcc peptide NA MH2 A B 38.838 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 Crystal structure of the 226 TCR in complex with MCC/I-Ek mus musculus mus musculus manduca sexta mus musculus mus musculus Kruse, A.C., Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 2.7 X-RAY DIFFRACTION 0.254 0.215 True 3bzd A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN 05/12/09 Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex mus musculus Cho, S. 2.3 X-RAY DIFFRACTION 0.258 0.210 True 4pj9 D C NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 57.047 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT TRAJ20 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.199 0.172 True 6c61 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV26 TRAV6 NA NA IMMUNE SYSTEM 01/30/19 MHC-independent T-cell receptor B12A mus musculus mus musculus Lu, J., Sun, P. 2.43 X-RAY DIFFRACTION 0.249 0.203 True 6w9u H G NA NA abTCR 0 A Hapten 1-[[6-(1-$l^{1}-oxidanylethyl)-4-$l^{3}-oxidanylidene-2,3,6,8~{a}-tetrahydropteridin-2-yl]-$l^{2}-azanyl]ethanone TKG MR1 A B 61.498 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 08/05/20 Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H-Ac-6-FP homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.89 X-RAY DIFFRACTION 0.197 0.162 True 5iw1 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV14 NA NA IMMUNE SYSTEM 03/29/17 Crystal Structure of B4.2.3 T-Cell Receptor mus musculus mus musculus Natarajan, K., Jiang, J., Margulies, D. 3.001 X-RAY DIFFRACTION 0.268 0.240 True 5wkf J I NA NA abTCR 0 H peptide gts1 peptide NA MH1 F G 37.633 TRBV11 TRAV30 NA NA IMMUNE SYSTEM 09/20/17 D30 TCR in complex with HLA-A*11:01-GTS1 homo sapiens homo sapiens dengue virus 1 homo sapiens homo sapiens Gras, S., Rossjohn, J. 2.95 X-RAY DIFFRACTION 0.253 0.190 True 8shi J I NA NA abTCR 0 F peptide val-arg-ser-arg-arg-aba-leu-arg-leu NA MH1 D E 21.379 TRBV6 TRAV17 NA NA IMMUNE SYSTEM 06/28/23 Valpha3S1 Vbeta13S1 HLA C 0602 VRSRRCLRL homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Littler, D.R., Anand, S., Vivian, J.P., Rossjohn, J. 2.90002 X-RAY DIFFRACTION 0.291 0.235 True 6vrn E D NA NA abTCR 0 P peptide cellular tumor antigen p53 peptide NA MH1 A B 33.725 TRBV10 TRAV38 NA NA IMMUNE SYSTEM 06/17/20 T cell receptor-p53-HLA-A2 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Gallagher, D.T., Gowthaman, R., Pierce, B.G., Mariuzza, R.A. 2.46 X-RAY DIFFRACTION 0.259 0.194 True 4pjf H G NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 59.717 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/09/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-C10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.45 X-RAY DIFFRACTION 0.212 0.178 True 2axh A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV19 NA NA NA IMMUNE SYSTEM 09/20/05 Crystal structures of T cell receptor beta chains related to rheumatoid arthritis homo sapiens Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y. 2.7 X-RAY DIFFRACTION 0.280 0.237 True 5d2n F C NA NA abTCR 0 G peptide asn-leu-val-pro-met-val-ala-thr-val NA MH1 H L 64.500 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 10/07/15 Crystal structure of C25-NLV-HLA-A2 complex homo sapiens homo sapiens cytomegalovirus homo sapiens homo sapiens Mariuzza, R.A., Yang, X. 2.099 X-RAY DIFFRACTION 0.253 0.204 True 3tvm D C NA NA abTCR 0 A Hapten N-[(2S,3R)-10-[(1R,2R)-2-DECYLCYCLOPROPYL]-1-(ALPHA-D-GALACTOPYRANOSYLOXY)-3-HYDROXYDECAN-2-YL]HEXACOSANAMIDE 07P CD1 A B 25.488 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 02/01/12 Structure of the mouse CD1d-SMC124-iNKT TCR complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Girardi, E., Li, Y., Zajonc, D.M. 2.8 X-RAY DIFFRACTION 0.273 0.224 True 3mc0 A NA NA NA NA 0 D protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 10/13/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, E.L. 2 X-RAY DIFFRACTION 0.211 0.179 True 2q86 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/01/08 Structure of the mouse invariant NKT cell receptor Valpha14 mus musculus mus musculus Zajonc, D.M. 1.85 X-RAY DIFFRACTION 0.223 0.179 True 3rdt B A NA NA abTCR 0 NA NA NA NA MH2 C D 40.757 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 12/07/11 Crystal Structure of 809.B5 TCR complexed with MHC Class II I-Ab/3k peptide mus musculus mus musculus mus musculus synthetic construct, mus musculus Trenh, P., Huseby, E.S., Stern, L.J. 2.7 X-RAY DIFFRACTION 0.241 0.206 True 3huj H G NA NA abTCR 0 A carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 A B 33.478 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 07/28/09 Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell receptor homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Pang, S.S. 2.5 X-RAY DIFFRACTION 0.279 0.216 True 5ksa D C NA NA abTCR 0 J peptide dq8.5-glia-gamma1 peptide NA MH2 A B 41.683 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 09/21/16 Bel602-DQ8.5-glia-gamma1 complex homo sapiens homo sapiens triticum aestivum homo sapiens triticum aestivum, homo sapiens Petersen, J., Rossjohn, J., Reid, H.H. 2 X-RAY DIFFRACTION 0.206 0.169 True 2cdf B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV27 NA NA CELL RECEPTOR 03/07/06 Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5E) homo sapiens homo sapiens Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y. 2.25 X-RAY DIFFRACTION 0.269 0.188 True 6mtm E D NA NA abTCR 0 C peptide np338 influenza peptide NA MH1 A B 50.170 TRBV19 TRAV30 NA NA IMMUNE SYSTEM 02/13/19 Crystal Structure of EM2 TCR in complex with HLA-B*37:01-NP338 homo sapiens homo sapiens unidentified influenza virus homo sapiens homo sapiens Gras, S. 3 X-RAY DIFFRACTION 0.301 0.218 True 2bnq E D NA NA abTCR 0 C peptide synthetic peptide NA MH1 A B 69.544 TRBV6 TRAV21 NA NA IMMUNE SYSTEM/RECEPTOR 05/23/05 Structural and kinetic basis for heightened immunogenicity of T cell vaccines homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Chen, J.-L., Stewart-Jones, G., Bossi, G., Lissin, N.M., Wooldridge, L., Choi, E.M.L., Held, G., Dunbar, P.R., Esnouf, R.M., Sami, M., Boultier, J.M., Rizkallah, P.J., Renner, C., Sewell, A., van der Merwe, P.A., Jackobsen, B.K., Griffiths, G., Jones, E.Y., Cerundolo, V. 1.7 X-RAY DIFFRACTION 0.253 0.226 True 3byt E NA NA NA NA 0 B protein enterotoxin type c-3 NA NA NA NA nan TRBV13 NA NA NA TOXIN 05/12/09 A complex between a variant of staphylococcal enterotoxin C3 and the variable domain of the murine T cell receptor beta chain 8.2 mus musculus staphylococcus aureus Cho, S., Eric, J.S. 2.3 X-RAY DIFFRACTION 0.278 0.226 True 8es7 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV14 NA NA IMMUNE SYSTEM 05/03/23 CryoEM structure of PN45545 TCR-CD3 complex homo sapiens homo sapiens Saotome, K., Franklin, M.C. 3.04 ELECTRON MICROSCOPY NA NA True 4z7v F E NA NA abTCR 0 I peptide deamidated dq8-glia-alpha1 peptide NA MH2 C D 39.673 TRBV9 TRAV26 NA NA IMMUNE SYSTEM 06/03/15 L3-12 complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Rossjohn, J., Reid, H.H., Koning, F. 2.65 X-RAY DIFFRACTION 0.226 0.187 True 4dzb B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV20 TRAV1 NA NA IMMUNE SYSTEM 03/28/12 Mucosal-associated invariant T cell receptor, Valpha7.2Jalpha33-Vbeta2 homo sapiens homo sapiens Patel, O., Rossjohn, J. 1.7 X-RAY DIFFRACTION 0.231 0.191 True 2f54 E D NA NA abTCR 0 C peptide cancer/testis antigen 1b NA MH1 A B 66.929 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 04/25/06 Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Jakobsen, B.K., Dunn, S.M., Sami, M. 2.7 X-RAY DIFFRACTION 0.286 0.221 True 5bs0 E D NA NA abTCR 0 C peptide titin NA MH1 A B 58.261 TRBV5 TRAV21 NA NA IMMUNE SYSTEM 03/02/16 MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Raman, M.C.C., Rizkallah, P.J., Simmons, R., Donellan, Z., Dukes, J., Bossi, G., LeProvost, G., Mahon, T., Hickman, E., Lomax, M., Oates, J., Hassan, N., Vuidepot, A., Sami, M., Cole, D.K., Jakobsen, B.K. 2.4 X-RAY DIFFRACTION 0.262 0.203 True 3rug F E NA NA abTCR 0 A Hapten (11E,14E)-N-[(2S,3S,4R)-1-(ALPHA-D-GLUCOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]ICOSA-11,14-DIENAMIDE DB6 CD1 A B 28.461 TRBV13 TRAV13 NA NA IMMUNE SYSTEM 08/03/11 Crystal structure of Valpha10-Vbeta8.1 NKT TCR in complex with CD1d-alphaglucosylceramide (C20:2) mus musculus mus musculus mus musculus mus musculus mus musculus Patel, O., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.254 0.210 True 4pj8 D C NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 53.525 TRBV20 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT TRBV20 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 3.3 X-RAY DIFFRACTION 0.213 0.163 True 7t2d T S NA NA abTCR 0 R peptide pneumolysin-derived peptide NA MH2 P Q 55.494 TRBV7 TRAV19 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the B1 TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.4 X-RAY DIFFRACTION 0.271 0.236 True 6cqr E D NA NA abTCR 0 C peptide peptide from capsid protein p24 NA MH2 A B 30.606 TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of F24 TCR -DR1-RQ13 peptide complex homo sapiens homo sapiens hiv-1 m homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 3.04 X-RAY DIFFRACTION 0.254 0.223 True 5m00 H G NA NA abTCR 0 P peptide lcmv-derived gp33 altered peptide ligand y4a NA MH1 A B 42.559 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 12/20/17 Crystal structure of murine P14 TCR complex with H-2Db and Y4A, modified gp33 peptide from LCMV mus musculus mus musculus mus musculus mus musculus mus musculus Achour, A., Sandalova, T., Sun, R., Han, X. 1.95 X-RAY DIFFRACTION 0.237 0.200 True 7n2q G E NA NA abTCR 0 J peptide yeih protein NA MH1 H I 21.042 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 AS4.3-YEIH-HLA*B27 homo sapiens homo sapiens escherichia coli homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.7 X-RAY DIFFRACTION 0.264 0.213 True 6fuo B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.7 X-RAY DIFFRACTION 0.200 0.168 True 7rm4 D E NA NA abTCR 0 C peptide cellular tumor antigen p53 peptide NA MH1 A B 35.580 TRBV11 TRAV6 NA NA IMMUNE SYSTEM 02/09/22 Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 3.33 X-RAY DIFFRACTION 0.295 0.237 True 4ei5 D C NA NA abTCR 0 A | I Hapten | carbohydrate (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE | N-ACETYL-D-GLUCOSAMINE CIS | NAG CD1 A B 73.808 TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Crystal Structure of XV19 TCR in complex with CD1d-sulfatide C24:1 mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Patel, O., Gras, S., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.227 0.197 True 6eqb E D NA NA abTCR 0 C peptide ala-ala-gly-ile-gly-ile-leu-thr-val NA MH1 A B 42.925 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 10/10/18 HLA class I histocompatibility antigen homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.81 X-RAY DIFFRACTION 0.251 0.183 True 7r7z B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV21 NA NA IMMUNE SYSTEM 06/29/22 Crystal structure of QW9-HLA-B*5301 specific T Cell Receptor, C3 homo sapiens homo sapiens Li, X.L., Tan, K.M., Xu, S.T., Ng, R., Walker, B.D., Wang, J.H. 2.286 X-RAY DIFFRACTION 0.252 0.215 True 8jbv NA NA m n gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV5 TRDV1 IMMUNE SYSTEM 05/08/24 Extracellular domain of gamma delta TCR homo sapiens homo sapiens Xin, W., Chi, X., Huang, B., Su, Q., Zhou, Q. 3.02 ELECTRON MICROSCOPY NA NA False 3dx9 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV26 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of the DM1 TCR at 2.75A homo sapiens homo sapiens Archbold, J.K., Macdonald, W.A., Gras, S., Rossjohn, J. 2.75 X-RAY DIFFRACTION 0.263 0.204 True 4p2r O N NA NA abTCR 0 M peptide 5c1 peptide NA MH2 K L 32.853 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.295 X-RAY DIFFRACTION 0.243 0.212 True 4p2q J I NA NA abTCR 0 H peptide 5c2 peptide NA MH2 F G 31.501 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.3 X-RAY DIFFRACTION 0.236 0.188 True 8i5c J I NA NA abTCR 0 H peptide tcr alpha chain NA MH1 F G 47.864 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 True 8dnt B A NA NA abTCR 0 D peptide nucleoprotein NA MH1 E F 32.142 NA NA NA NA IMMUNE SYSTEM 01/08/09 SARS-CoV-2 specific T cell receptor homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Gallagher, D.T., Wu, D., Gowthaman, R., Pierce, B.G., Mariuzza, R.A., Weng, N.P. 3.18 X-RAY DIFFRACTION 0.313 0.221 True 6uk4 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV38 NA NA IMMUNE SYSTEM 08/19/20 Complex of T cell Receptor with HHAT Neoantigen Peptide KQWLVWLFL Presented by HLA-A206 homo sapiens homo sapiens Devlin, J.R., Baker, B.M. 2.7 X-RAY DIFFRACTION 0.252 0.220 True 5e6i Q P NA NA abTCR 0 T peptide matrix protein 1 NA MH1 R U 66.284 TRBV27 TRAV35 NA NA IMMUNE SYSTEM 10/19/16 Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Gao, M., Mariuzza, R. 4 X-RAY DIFFRACTION 0.338 0.259 True 1sbb C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/01/99 T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB mus musculus Li, H., Mariuzza, R.A. 2.4 X-RAY DIFFRACTION 0.309 0.228 True 4mng NA NA F f gdTCR 0 C Hapten (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE CIS CD1 C D 38.826 NA NA TRGV4 TRDV1 IMMUNE SYSTEM 12/18/13 Structure of the DP10.7 TCR with CD1d-sulfatide homo sapiens mus musculus mus musculus mus musculus Luoma, A.M., Adams, E.J. 3.0058 X-RAY DIFFRACTION 0.207 0.178 True 7ea6 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV11 TRAV12 NA NA IMMUNE SYSTEM 10/13/21 Crystal structure of TCR-017 ectodomain homo sapiens homo sapiens Nagae, M., Yamasaki, S. 2.18 X-RAY DIFFRACTION 0.276 0.222 True 2vlm E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV19 TRAV27 NA NA IMMUNE SYSTEM 01/22/08 The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain homo sapiens homo sapiens Ishizuka, J., Stewart-Jones, G., Van der Merwe, A., Bell, J., McMichael, A., Jones, Y. 1.98 X-RAY DIFFRACTION 0.279 0.204 True 5tje F E NA NA abTCR 0 J peptide peptide gp33-41 from lcmv NA MH1 C D 46.057 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 11/01/17 Murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 and T cell receptor P14 mus musculus mus musculus lymphocytic choriomeningitis virus mus musculus mus musculus Achour, A., Sandalova, T., Allerbring, E., Popov, A. 3.2 X-RAY DIFFRACTION 0.314 0.228 True 3q5y C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV12 NA NA NA IMMUNE SYSTEM 03/09/11 V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures mus musculus Chen, Q., Zhang, H., Wang, J.-H. 1.9 X-RAY DIFFRACTION 0.218 0.178 True 6dfq B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV1 TRAV10 NA NA IMMUNE SYSTEM 04/17/19 mouse diabetogenic TCR I.29 mus musculus mus musculus Wang, Y., Dai, S. 2.6 X-RAY DIFFRACTION 0.253 0.220 True 6fr8 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.38 X-RAY DIFFRACTION 0.278 0.222 True 2j8u M L NA NA abTCR 0 J peptide self-peptide p1049 NA MH1 H I 66.039 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 10/16/07 Large CDR3a loop alteration as a function of MHC mutation. mus musculus mus musculus homo sapiens homo sapiens homo sapiens Miller, P.J., Benhar, Y.P., Biddison, W., Collins, E.J. 2.88 X-RAY DIFFRACTION 0.293 0.268 True 2aq2 A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 1.8 X-RAY DIFFRACTION 0.213 0.185 True 3tf7 K k NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 QL9/H2-Ld complex mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 2.75 X-RAY DIFFRACTION 0.261 0.237 True 3ard D C NA NA abTCR 0 A Hapten N-{(2S,3R)-1-[(3-DEOXY-ALPHA-D-XYLO-HEXOPYRANOSYL)OXY]-3-HYDROXYOCTADECAN-2-YL}HEXACOSANAMIDE 3GH CD1 A B 23.818 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 03/30/11 Ternary crystal structure of the mouse NKT TCR-CD1d-3'deoxy-alpha-galactosylceramide mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wun, K.S., Rossjohn, J. 3.01 X-RAY DIFFRACTION 0.277 0.213 True 5u16 H G NA NA abTCR 0 A Hapten 2-HYDROXYNAPHTHALENE-1-CARBALDEHYDE 7WO MR1 A B 62.294 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/15/17 Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.219 0.173 True 1lp9 M L NA NA abTCR 0 J peptide self-peptide p1049 NA MH1 H I 65.682 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 11/11/03 Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1 mus musculus mus musculus homo sapiens homo sapiens Buslepp, J., Wang, H., Biddison, W.E., Appella, E., Collins, E.J. 2 X-RAY DIFFRACTION 0.253 0.219 True 1l0x A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 04/03/02 TCR beta chain complexed with streptococcal superantigen SpeA mus musculus Li, H., Sundberg, E.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.278 0.232 True 4gg8 F E NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV9 TRAV26 NA NA IMMUNE SYSTEM 10/24/12 Immune Receptor homo sapiens homo sapiens Broughton, S.E., Theodossis, A., Petersen, J., Reid, H.H., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.308 0.261 True 3kps E D NA NA abTCR 0 C peptide eeylqafty, self peptide from the atp binding cassetteprotein abcd3 NA MH1 A B 43.177 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 12/22/09 Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLQAFTY a self peptide from the ABCD3 protein homo sapiens homo sapiens homo sapiens homo sapiens Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J. 2.7 X-RAY DIFFRACTION 0.269 0.193 True 6puf E D NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C F 57.985 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-5'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.92 X-RAY DIFFRACTION 0.221 0.178 True 2bnr E D NA NA abTCR 0 C peptide synthetic peptide NA MH1 A B 69.699 TRBV6 TRAV21 NA NA IMMUNE SYSTEM/RECEPTOR 05/23/05 Structural and kinetic basis for heightened immunogenicity of T cell vaccines homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Chen, J.-L., Stewart-Jones, G., Bossi, G., Lissin, N.M., Wooldridge, L., Choi, E.M.L., Held, G., Dunbar, P.R., Esnouf, R.M., Sami, M., Boultier, J.M., Rizkallah, P.J., Renner, C., Sewell, A., van der Merwe, P.A., Jackobsen, B.K., Griffiths, G., Jones, E.Y., Cerundolo, V. 1.9 X-RAY DIFFRACTION unknown 0.231 True 7amr B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 04/20/22 Crystal structure of the complex of the KFN mutant of Jovi-1 Fab with human TRBC1 homo sapiens homo sapiens Ferrari, M., Bulek, A., Bughda, R., Jha, R., Welin, M., Logan, D.T., Sewell, A., Onuoha, S., Pule, M. 1.949 X-RAY DIFFRACTION 0.225 0.179 True 5w1w T S NA NA abTCR 0 R peptide leader peptide of hla class i histocompatibility antigen, aalpha chain NA MH1 P Q 68.487 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.263 0.215 True 3kpr J I NA NA abTCR 0 H peptide eeylkawtf, mimotope peptide NA MH1 F G 45.470 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 12/22/09 Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope homo sapiens homo sapiens homo sapiens homo sapiens Macdonald, W.A., Chen, Z., Gras, S., Archbold, J.K., Tynan, F.E., Clements, C.S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P.M., Wilce, M.C., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A.G., Purcell, A.W., Kappler, J.W., Burrows, S.R., Rossjohn, J., McCluskey, J. 2.6 X-RAY DIFFRACTION 0.279 0.219 True 2ij0 C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV20 NA NA NA PROTEIN BINDING 02/20/07 Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1 homo sapiens Moza, B., Varma, A.K., Buonpane, R.A., Zhu, P., Herfst, C.A., Nicholson, M.J., Wilbuer, A.K., Nulifer, S., Wucherpfenning, K.W., McCormick, J.K., Kranz, D.M., Sundberg, E.J. 2.25 X-RAY DIFFRACTION 0.252 0.242 True 6rpb T S NA NA abTCR 0 R peptide heteroclitic ny-eso-1 157-165 peptide NA MH1 P Q 69.288 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 2.5 X-RAY DIFFRACTION 0.273 0.249 True 1nfd D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV12 NA NA COMPLEX (IMMUNORECEPTOR/IMMUNOGLOBULIN) 01/28/98 AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY mus musculus mus musculus Wang, J.-H., Lim, K., Smolyar, A., Teng, M.-K., Sacchittini, J., Reinherz, E.L. 2.8 X-RAY DIFFRACTION 0.309 0.243 True 3owe I NA NA NA NA 0 F protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 3qeu E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/06/11 The crystal structure of TCR DMF5 homo sapiens homo sapiens Borbulevych, O.Y., Santhanagopolan, S.M., Baker, B.M. 2.09 X-RAY DIFFRACTION 0.266 0.206 True 4lfh NA NA D G gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV5 TRDV1 IMMUNE SYSTEM 10/02/13 Crystal Structure of 9C2 TCR homo sapiens homo sapiens Uldrich, A.P., Le Nours, J., Pellicci, D.G., Gras, S., Rossjohn, J., Godfrey, D.I. 2.3 X-RAY DIFFRACTION 0.238 0.187 True 3q5y A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV12 NA NA NA IMMUNE SYSTEM 03/09/11 V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures mus musculus Chen, Q., Zhang, H., Wang, J.-H. 1.9 X-RAY DIFFRACTION 0.218 0.178 True 8dnt W V NA NA abTCR 0 X peptide nucleoprotein NA MH1 Y Z 30.959 NA NA NA NA IMMUNE SYSTEM 01/08/09 SARS-CoV-2 specific T cell receptor homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Gallagher, D.T., Wu, D., Gowthaman, R., Pierce, B.G., Mariuzza, R.A., Weng, N.P. 3.18 X-RAY DIFFRACTION 0.313 0.221 True 6cql E D NA NA abTCR 0 C peptide peptide from capsid protein p24 NA MH2 A B 33.458 TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of F24 TCR -DR11-RQ13 peptide complex homo sapiens homo sapiens hiv-1 m homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.256 0.220 True 7pdw G F NA NA abTCR 0 J peptide unknown NA MH1 H I 32.868 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 Crystal structure of parent TCR (728) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide Simister, P.C., Border, E.C., Vieira, J.F., Pumphrey, N.J. 1.82 X-RAY DIFFRACTION 0.229 0.201 False 3pqy O N NA NA abTCR 0 M peptide 10-mer peptide from rna-directed rna polymerase NA MH1 K L 45.655 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 05/18/11 Crystal Structure of 6218 TCR in complex with the H2Db-PA224 mus musculus, homo sapiens mus musculus, homo sapiens synthetic construct mus musculus mus musculus Gras, S., Guillonneau, C., Turner, S.J., Rossjohn, J. 3.192 X-RAY DIFFRACTION 0.316 0.246 True 4lcw H G NA NA abTCR 0 A Hapten 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol 1VY MR1 A B 58.818 TRBV6 TRAV1 NA NA Membrane Protein/Immune System 10/02/13 The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Patel, O., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.227 0.179 True 7t2d J I NA NA abTCR 0 H peptide pneumolysin-derived peptide NA MH2 F G 55.408 TRBV7 TRAV19 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the B1 TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.4 X-RAY DIFFRACTION 0.271 0.236 True 5c09 J I NA NA abTCR 0 H peptide marker peptide NA MH1 F G 46.241 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 HLA class I histocompatibility antigen homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.475 X-RAY DIFFRACTION 0.259 0.205 True 4mxq D C NA NA abTCR 0 B peptide pcpc5 NA MH1 A NA 47.771 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 08/19/15 42F3 TCR pCPC5/H-2Ld Complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 2.596 X-RAY DIFFRACTION 0.240 0.211 True 6vtc B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV27 TRAV12 NA NA IMMUNE SYSTEM 06/17/20 p53-specific T cell receptor homo sapiens homo sapiens Wu, D., Gallagher, D.T., Gowthaman, R., Pierce, B.G., Mariuzza, R.A. 1.83 X-RAY DIFFRACTION 0.231 0.190 True 5d7j H G NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 59.044 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-5-OP-RU in complex with human MAIT M33.64(Y95alphaF) TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Woolley, R.E., Rossjohn, J. 1.97 X-RAY DIFFRACTION 0.222 0.179 True 5jzi E D NA NA abTCR 0 C peptide klv peptide NA MH1 A B 30.434 TRBV25 TRAV38 NA NA Protein binding/Immune System 05/31/17 Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide homo sapiens homo sapiens hepatitis c virus homo sapiens homo sapiens Wang, Y., Piepenbrink, K.H., Baker, B.M. 2.5 X-RAY DIFFRACTION 0.232 0.196 True 6omg D C NA NA abTCR 0 A Hapten (2R)-1-(alpha-D-glucopyranosyloxy)-3-(octadecanoyloxy)propan-2-yl (9Z)-octadec-9-enoate MVV CD1 A B 25.705 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/22/20 Structure of mouse CD1D- Glc-DAG (sn-1 C18:0, sn-2 C18:1c9)-iNKT TCR Ternary complex mus musculus mus musculus mus musculus mus musculus mus musculus Dirk, M.Z., Bitra, A., Wang, J. 2.1 X-RAY DIFFRACTION 0.227 0.186 True 3sjv T S NA NA abTCR 0 R peptide epstein-barr nuclear antigen 3 NA MH1 P Q 38.912 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR in complex with HLA-B8-FLR homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.321 0.253 True 1qrn E D NA NA abTCR 0 C peptide tax peptide p6a NA MH1 A B 33.739 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 10/14/99 CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A homo sapiens homo sapiens homo sapiens homo sapiens Ding, Y.H., Baker, B.M., Garboczi, D.N., Biddison, W.E., Wiley, D.C. 2.8 X-RAY DIFFRACTION 0.273 0.216 True 2p1y E e NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV14 NA NA IMMUNE SYSTEM 02/05/08 1.B2.D9, a bispecific alpha/beta TCR mus musculus McBeth, C., Pizarro, J.C., Strong, R.K. 2.42 X-RAY DIFFRACTION 0.254 0.181 True 3kxf E D NA NA abTCR 0 Q peptide peptide from trans-activator protein bzlf1 NA MH1 A B 69.885 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Tynan, F.E., Gras, S., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.291 0.213 True 3pl6 D C NA NA abTCR 0 NA NA NA NA MH2 A B 25.659 TRBV7 TRAV13 NA NA IMMUNE SYSTEM 12/22/10 Structure of Autoimmune TCR Hy.1B11 in complex with HLA-DQ1 and MBP 85-99 homo sapiens homo sapiens homo sapiens homo sapiens Sethi, D.K., Wucherpfennig, K.W. 2.55 X-RAY DIFFRACTION 0.258 0.232 True 2p1y A c NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV14 NA NA IMMUNE SYSTEM 02/05/08 1.B2.D9, a bispecific alpha/beta TCR mus musculus McBeth, C., Pizarro, J.C., Strong, R.K. 2.42 X-RAY DIFFRACTION 0.254 0.181 True 3ta3 D C NA NA abTCR 0 A Hapten (2S)-1-(ALPHA-D-GLUCOPYRANOSYLOXY)-3-(HEXADECANOYLOXY)PROPAN-2-YL (11Z)-OCTADEC-11-ENOATE 3TF CD1 A B 25.558 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 11/23/11 Structure of the mouse CD1d-Glc-DAG-s2-iNKT TCR complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Girardi, E., Yu, E.D., Zajonc, D.M. 2.7 X-RAY DIFFRACTION 0.256 0.205 True 4pjh F E NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 58.891 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-G8 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.198 0.169 True 5c0a E D NA NA abTCR 0 C peptide marker peptide NA MH1 A B 45.944 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying MVW peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.46 X-RAY DIFFRACTION 0.232 0.193 True 3kxf H G NA NA abTCR 0 R peptide peptide from trans-activator protein bzlf1 NA MH1 C F 67.023 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Tynan, F.E., Gras, S., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.291 0.213 True 8i5c x w NA NA abTCR 0 v peptide unknown NA MH1 t u 47.055 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 False 5c09 E D NA NA abTCR 0 C peptide marker peptide NA MH1 A B 44.449 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 HLA class I histocompatibility antigen homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.475 X-RAY DIFFRACTION 0.259 0.205 True 6p64 J I NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV38 NA NA IMMUNE SYSTEM 06/03/20 Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206 homo sapiens homo sapiens Devlin, J.R., Baker, B.M. 3.05 X-RAY DIFFRACTION 0.219 0.194 True 4ndm NA NA B A gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV5 TRDV1 IMMUNE SYSTEM 12/18/13 Structure of the AB18.1 TCR homo sapiens homo sapiens Luoma, A.M., Adams, E.J. 3.0065 X-RAY DIFFRACTION 0.280 0.242 True 4z7u F E NA NA abTCR 0 I peptide deamidated dq8-glia-alpha1 peptide NA MH2 C D 36.414 TRBV9 TRAV26 NA NA IMMUNE SYSTEM 06/03/15 S13 complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Rossjohn, J., Reid, H.H., Koning, F. 2.7 X-RAY DIFFRACTION 0.220 0.178 True 7n2n F D NA NA abTCR 0 C peptide pre-mrna processing factor 3 NA MH1 A B 21.514 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 TCR-antigen complex AS4.2-PRPF3-HLA*B27 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.6 X-RAY DIFFRACTION 0.291 0.248 True 6bnl D C NA NA abTCR 0 A Hapten N-[(2S,3R)-3-hydroxy-1-{[6-O-(3-phenylpropanoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide QWV CD1 A B 27.114 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/04/18 Crystal structure of TCR-MHC-like molecule mus musculus homo sapiens mus musculus mus musculus mus musculus Le Nours, J., Rossjohn, J. 2.6 X-RAY DIFFRACTION 0.214 0.181 True 8es9 B A NA NA abTCR 0 P peptide melanoma-associated antigen 4 NA MH1 N M 84.863 TRBV20 TRAV20 NA NA IMMUNE SYSTEM 05/03/23 CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Saotome, K., Franklin, M.C. 3.25 ELECTRON MICROSCOPY NA NA True 3e3q N M NA NA abTCR 0 O peptide ql9 peptide NA MH1 L NA 45.262 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 5yxu G F NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV38 NA NA IMMUNE SYSTEM 12/12/18 an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV homo sapiens homo sapiens Yi, L. 2.7 X-RAY DIFFRACTION 0.289 0.235 True 2nx5 U T NA NA abTCR 0 S peptide ebv peptide, eplpqgqltay NA MH1 Q R 58.909 TRBV10 TRAV1 NA NA IMMUNE SYSTEM 02/27/07 Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Reid, H.H., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.327 0.269 True 1g6r B A NA NA abTCR 0 P peptide siyr peptide NA MH1 H L 22.609 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/15/00 A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX mus musculus mus musculus mus musculus mus musculus Degano, M., Garcia, K.C., Apostolopoulos, V., Rudolph, M.G., Teyton, L., Wilson, I.A. 2.8 X-RAY DIFFRACTION 0.327 0.298 True 5xov H NA NA NA NA 0 G | F protein | peptide v-delta chain of t cell receptor | hiv-1 nef138-10 peptide NA | NA MH1 D E nan TRBV30 NA NA NA IMMUNE SYSTEM 06/14/17 Crystal structure of peptide-HLA-A24 bound to S19-2 V-delta/V-beta TCR homo sapiens homo sapiens | human immunodeficiency virus 1 homo sapiens homo sapiens Shi, Y., Qi, J., Gao, G.F. 2.684 X-RAY DIFFRACTION 0.245 0.203 True 7llj NA NA NA A NA 0 B protein t cell receptor delta variable 3 NA MR1 E F nan NA NA TRGV8 NA IMMUNE SYSTEM 11/17/21 Inhibitory immune receptor protein complex homo sapiens homo sapiens homo sapiens homo sapiens Rice, M.T., Littler, D.R., Rossjohn, J., Gully, B.S. 3.15 X-RAY DIFFRACTION 0.276 0.241 True 2po6 H G NA NA abTCR 0 E carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 E F 31.156 TRBV25 TRAV10 NA NA LIPID BINDING PROTEIN/IMMUNE SYSTEM 07/03/07 Crystal structure of CD1d-lipid-antigen complexed with Beta-2-Microglobulin, NKT15 Alpha-Chain and NKT15 Beta-Chain homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Borg, N.A. 3.2 X-RAY DIFFRACTION 0.293 0.226 True 4zak D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanethioamide 4LX CD1 A B 25.399 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 07/01/15 Crystal structure of the mCD1d/DB06-1/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Birkholz, A.M. 2.824 X-RAY DIFFRACTION 0.256 0.216 True 8gvb B A NA NA abTCR 0 P peptide 8-mer peptide from protein nef NA MH1 H L 57.795 TRBV7 TRAV8 NA NA IMMUNE SYSTEM 10/19/22 The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 peptide homo sapiens homo sapiens hiv-1 06tg.ht008 homo sapiens homo sapiens Gao, G.F., Shi, Y., Ma, K., Chai, Y., Guan, J., Qi, J., Tan, S., Dong, T., Iwamoto, A., Kawana-Tachikawa, A. 3.2 X-RAY DIFFRACTION 0.321 0.280 True 6v80 D C NA NA abTCR 0 A | E carbohydrate | protein N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE | nanobody vhh id12 AGH | NA CD1 A B 30.306 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 09/16/20 Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12 homo sapiens homo sapiens homo sapiens | lama glama homo sapiens homo sapiens Shahine, A., Rossjohn, J. 3.53 X-RAY DIFFRACTION 0.254 0.195 True 6fum B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.76 X-RAY DIFFRACTION 0.223 0.181 True 5d7i F E NA NA abTCR 0 C Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 C D 61.321 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Woolley, R.E., Rossjohn, J. 2 X-RAY DIFFRACTION 0.220 0.178 True 8trl H G NA NA abTCR 0 F peptide alpha-enolase NA MH2 D E 33.331 TRBV2 TRAV26 NA NA IMMUNE SYSTEM 07/31/24 T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Lim, J.J., Loh, T.J., Reid, H.H., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.234 0.210 True 8tfn B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 11/08/23 Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR homo sapiens homo sapiens Katragadda, M., Servatalab, R., Wirth, J. 2.54 X-RAY DIFFRACTION 0.294 0.245 True 5d2l F E NA NA abTCR 0 R peptide asn-leu-val-pro-met-val-ala-thr-val NA MH1 C D 27.697 TRBV7 TRAV24 NA NA IMMUNE SYSTEM 10/07/15 Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2 homo sapiens homo sapiens cytomegalovirus homo sapiens homo sapiens Gao, M., Mariuzza, R.A. 3.511 X-RAY DIFFRACTION 0.355 0.270 True 4y16 D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-1-{[6-O-(naphthalen-1-ylcarbamoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide 48G CD1 A B 24.533 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 06/03/15 Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Nemcovic, M. 2.6 X-RAY DIFFRACTION 0.244 0.211 True 2p1y C a NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV14 NA NA IMMUNE SYSTEM 02/05/08 1.B2.D9, a bispecific alpha/beta TCR mus musculus McBeth, C., Pizarro, J.C., Strong, R.K. 2.42 X-RAY DIFFRACTION 0.254 0.181 True 6fur B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.73 X-RAY DIFFRACTION 0.226 0.189 True 4p4k D C NA NA abTCR 0 NA NA NA NA MH2 A B 47.102 TRBV5 TRAV9 NA NA IMMUNE SYSTEM 07/16/14 Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity and auto immunity homo sapiens homo sapiens homo sapiens homo sapiens Clayton, G.M., Crawford, F., Kappler, J.W. 2.8 X-RAY DIFFRACTION 0.252 0.204 True 5xov J NA NA NA NA 0 I | C protein | peptide v-delta chain of t cell receptor | hiv-1 nef138-10 peptide NA | NA MH1 A B nan TRBV30 NA NA NA IMMUNE SYSTEM 06/14/17 Crystal structure of peptide-HLA-A24 bound to S19-2 V-delta/V-beta TCR homo sapiens homo sapiens | human immunodeficiency virus 1 homo sapiens homo sapiens Shi, Y., Qi, J., Gao, G.F. 2.684 X-RAY DIFFRACTION 0.245 0.203 True 6bnl H G NA NA abTCR 0 E Hapten N-[(2S,3R)-3-hydroxy-1-{[6-O-(3-phenylpropanoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide QWV CD1 E F 25.863 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/04/18 Crystal structure of TCR-MHC-like molecule mus musculus homo sapiens mus musculus mus musculus mus musculus Le Nours, J., Rossjohn, J. 2.6 X-RAY DIFFRACTION 0.214 0.181 True 7fjf n m NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/27/22 Cryo-EM structure of a membrane protein(CS) homo sapiens homo sapiens Chen, Y., Zhu, Y., Gao, W., Zhang, A., Guo, C., Huang, Z. 3.1 ELECTRON MICROSCOPY NA NA False 5wlg J I NA NA abTCR 0 H peptide gap50 peptide NA MH1 F G 24.553 TRBV13 TRAV8 NA NA IMMUNE SYSTEM 11/15/17 Crystal Structure of H-2Db with the GAP501 peptide (SQL) mus musculus, homo sapiens mus musculus, homo sapiens plasmodium berghei mus musculus mus musculus Gras, S., Farenc, C., Josephs, T., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.249 0.218 True 2aq1 G NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.1 X-RAY DIFFRACTION 0.243 0.185 True 5nmg E D NA NA abTCR 0 C peptide gag protein NA MH1 A B 52.463 TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR in complex with HLA A02 presenting SLYFNTIAVL homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.75 X-RAY DIFFRACTION 0.254 0.196 True 7dzm D E NA NA abTCR 0 C peptide gag-pol polyprotein NA MH1 A B 43.721 TRBV12 TRAV26 NA NA IMMUNE SYSTEM 01/26/22 Crystal Structure of the cross-restricted T18A TCR and HLAB8101 bound to HIV-1 Gag TL9 peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Liu, Y., Yin, L. 2.25 X-RAY DIFFRACTION 0.240 0.196 True 2nx5 J I NA NA abTCR 0 M peptide ebv peptide, eplpqgqltay NA MH1 F G 58.903 TRBV10 TRAV1 NA NA IMMUNE SYSTEM 02/27/07 Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Reid, H.H., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.327 0.269 True 5iw1 F E NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV14 NA NA IMMUNE SYSTEM 03/29/17 Crystal Structure of B4.2.3 T-Cell Receptor mus musculus mus musculus Natarajan, K., Jiang, J., Margulies, D. 3.001 X-RAY DIFFRACTION 0.268 0.240 True 4may D C NA NA abTCR 0 NA NA NA NA MH2 A B 25.732 TRBV7 TRAV13 NA NA IMMUNE SYSTEM 10/23/13 Crystal structure of an immune complex unidentified herpesvirus, homo sapiens homo sapiens homo sapiens homo sapiens Sethi, D.K., Wucherpfennig, K.W. 2.2 X-RAY DIFFRACTION 0.236 0.196 True 3quz D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-({6-DEOXY-6-[(NAPHTHALEN-1-YLCARBAMOYL)AMINO]-ALPHA-D-GALACTOPYRANOSYL}OXY)-3,4-DIHYDROXYOCTADECAN-2-YL]HEXACOSANAMIDE QUV CD1 A B 24.710 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 06/29/11 Structure of the mouse CD1d-NU-alpha-GalCer-iNKT TCR complex mus musculus mus musculus mus musculus mus musculus mus musculus Li, Y., Girardi, E., Yu, E.D., Zajonc, D.M. 2.3 X-RAY DIFFRACTION 0.233 0.192 True 4nqc H G NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 61.399 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TCR-MR1 ternary complex and covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.216 0.165 True 8jcb NA NA M N gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV5 TRDV1 IMMUNE SYSTEM 05/08/24 Vgamma5 Vdelta1 T cell receptor complex homo sapiens homo sapiens Xin, W., Huang, B., Chi, X., Xu, M., Zhang, Y., Li, X., Su, Q., Zhou, Q. 9.5 ELECTRON MICROSCOPY NA NA True 7byd J I NA NA abTCR 0 H peptide gly-gly-ala-ile NA MH1 F G 30.513 TRBV3 TRAV4 NA NA IMMUNE SYSTEM 03/31/21 Crystal structure of SN45 TCR in complex with lipopeptide-bound Mamu-B*05104 macaca mulatta macaca mulatta simian immunodeficiency virus macaca mulatta macaca mulatta Morita, D., Sugita, M., Iwashita, C. 2.80003 X-RAY DIFFRACTION 0.250 0.185 True 7lli NA NA NA E NA 0 F protein t cell receptor delta variable 3 NA MR1 A B nan NA NA TRGV8 NA IMMUNE SYSTEM 11/17/21 Stimulatory immune receptor protein complex homo sapiens homo sapiens homo sapiens homo sapiens Rice, M.T., Littler, D.R., Rossjohn, J., Gully, B.S. 3.2 X-RAY DIFFRACTION 0.263 0.244 True 5hho E D NA NA abTCR 0 C peptide m1-g4e, gilefvftl NA MH1 A B 64.330 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 03/23/16 Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-G4E homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Gras, S., Josephs, T.M., Rossjohn, J. 2.95 X-RAY DIFFRACTION 0.279 0.236 True 1qse E D NA NA abTCR 0 C peptide tax peptide v7r NA MH1 A B 36.974 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 12/21/99 STRUCTURE OF HUMAN A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE V7R homo sapiens homo sapiens homo sapiens homo sapiens Ding, Y.H., Baker, B.M., Garboczi, D.N., Biddison, W.E., Wiley, D.C. 2.8 X-RAY DIFFRACTION 0.290 0.243 True 3c6l F E NA NA abTCR 0 NA NA NA NA MH2 G H 42.801 TRBV13 TRAV14 NA NA SUGAR BINDING PROTEIN/IMMUNE SYSTEM 04/29/08 Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20 mus musculus mus musculus mus musculus mus musculus Dai, S. 3.4 X-RAY DIFFRACTION 0.325 0.268 True 5d5m H G NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 58.601 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Birkinshaw, R.W., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.222 0.171 True 5hyj J I NA NA abTCR 0 H peptide ala-gln-trp-gly-pro-asp-pro-ala-ala-ala NA MH1 F G 48.469 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 3.06 X-RAY DIFFRACTION 0.294 0.212 True 4mnh NA NA B A gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV4 TRDV1 IMMUNE SYSTEM 12/18/13 Structure of the DP10.7 TCR homo sapiens homo sapiens Luoma, A.M., Adams, E.J. 3.3 X-RAY DIFFRACTION 0.285 0.231 True 3sjv E D NA NA abTCR 0 C peptide epstein-barr nuclear antigen 3 NA MH1 A B 37.463 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR in complex with HLA-B8-FLR homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.321 0.253 True 2nx5 E D NA NA abTCR 0 C peptide ebv peptide, eplpqgqltay NA MH1 A B 56.703 TRBV10 TRAV1 NA NA IMMUNE SYSTEM 02/27/07 Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Reid, H.H., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.327 0.269 True 3owe O NA NA NA NA 0 D protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 6miy H G NA NA abTCR 0 E Hapten N-{(2S,3S,4R)-1-[(4-O-benzyl-alpha-D-galactopyranosyl)oxy]-3,4-dihydroxyoctadecan-2-yl}hexacosanamide JTV CD1 E F 25.719 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxa (JJ239)/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2.75 X-RAY DIFFRACTION 0.247 0.192 True 3rgv B A NA NA abTCR 0 E peptide peptide NA MH1 C D 52.620 TRBV13 TRAV6 NA NA IMMUNE SYSTEM 07/20/11 A single TCR bound to MHCI and MHC II reveals switchable TCR conformers mus musculus mus musculus mus musculus mus musculus mus musculus Dai, S., Huseby, E., Scott-Browne, J., Rubtsova, K., Pinilla, C., Crawford, F., Marrack, P., Yin, L., Kappler, J.W. 2.9 X-RAY DIFFRACTION 0.254 0.202 True 1h5b NA C NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV4 NA NA T CELL RECEPTOR 06/21/01 T cell receptor Valpha11 (AV11S5) domain mus musculus Machius, M., Cianga, P., Deisenhofer, J., Sally Ward, E. 1.85 X-RAY DIFFRACTION 0.245 0.224 True 3c5z F E NA NA abTCR 0 NA NA NA NA MH2 G H 49.246 TRBV13 TRAV6 NA NA SUGAR BINDING PROTEIN/IMMUNE SYSTEM 04/29/08 Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506 mus musculus mus musculus mus musculus mus musculus Dai, S., Kappler, J. 2.55 X-RAY DIFFRACTION 0.281 0.246 True 2e7l C B NA NA abTCR 0 P peptide peptide (gln)(leu)(ser)(pro)(phe)(pro)(phe)(asp)(leu) NA MH1 F NA 45.544 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 04/24/07 Structure of a high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Garcia, K.C., Colf, L.A. 2.5 X-RAY DIFFRACTION 0.246 0.224 True 5w1v E D NA NA abTCR 0 C peptide vmaprtlil peptide from cmv gpul40 NA MH1 A B 69.343 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex homo sapiens homo sapiens human herpesvirus 5 strain ad169 homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.31 X-RAY DIFFRACTION 0.268 0.225 True 2cde D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA CELL RECEPTOR 03/07/06 Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR homo sapiens homo sapiens Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y. 3.5 X-RAY DIFFRACTION 0.3504 0.2830 True 5nmd B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR Specific for HLA A02 presenting HIV Epitope SLYNTVATL homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.07 X-RAY DIFFRACTION 0.223 0.189 True 4gkz B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV8 NA NA IMMUNE SYSTEM 11/07/12 HA1.7, a MHC class II restricted TCR specific for haemagglutinin homo sapiens homo sapiens Holland, C.J., Rizkallah, P.J., Cole, D.K., Sewell, A.K., Godkin, A.J. 2.39 X-RAY DIFFRACTION 0.298 0.249 True 1ac6 NA B NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV6 NA NA RECEPTOR 02/25/98 CRYSTAL STRUCTURE OF A VARIABLE DOMAIN MUTANT OF A T-CELL RECEPTOR ALPHA CHAIN mus musculus Li, H.-M., Mariuzza, R.A. 2.3 X-RAY DIFFRACTION 0.279 0.161 False 1g6r D C NA NA abTCR 0 Q peptide siyr peptide NA MH1 I M 23.557 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/15/00 A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX mus musculus mus musculus mus musculus mus musculus Degano, M., Garcia, K.C., Apostolopoulos, V., Rudolph, M.G., Teyton, L., Wilson, I.A. 2.8 X-RAY DIFFRACTION 0.327 0.298 True 3mbe H G NA NA abTCR 0 Q peptide peptide hel 11-27 NA MH2 E F 48.061 TRBV13 TRAV4 NA NA IMMUNE SYSTEM 05/12/10 TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27) mus musculus mus musculus gallus gallus mus musculus mus musculus Corper, A.L., Yoshida, K., Teyton, L., Wilson, I.A. 2.886 X-RAY DIFFRACTION 0.281 0.253 True 4pjd H G NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 60.243 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT C-C10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.78 X-RAY DIFFRACTION 0.226 0.168 True 5m01 H G NA NA abTCR 0 P peptide lcmv-derived gp33 altered peptide ligand pa NA MH1 A B 42.675 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 10/25/17 Crystal structure of murine P14 TCR/ H-2Db complex with PA, modified gp33 peptide from LCMV mus musculus mus musculus lymphocytic choriomeningitis virus mus musculus mus musculus Achour, A., Sandalova, T., Sun, R., Han, X. 1.95 X-RAY DIFFRACTION 0.229 0.196 True 3tf7 C c NA NA abTCR 0 B peptide ql9 peptide (qlspfpfdl) NA MH1 A NA 50.508 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 QL9/H2-Ld complex mus musculus mus musculus mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 2.75 X-RAY DIFFRACTION 0.261 0.237 True 7l15 NA NA NA B NA 0 A | A protein | carbohydrate t cell receptor mu chain | N-ACETYL-D-GLUCOSAMINE NA | NAG NA NA NA nan NA NA NA NA IMMUNE SYSTEM 03/24/21 Marsupial T cell receptor Spl_118 monodelphis domestica monodelphis domestica | monodelphis domestica Wegrecki, M., Kannan Sivaraman, K., Praveena, T., Le Nours, J., Rossjohn, J. 2.25 X-RAY DIFFRACTION 0.227 0.181 True 8wul B A NA NA abTCR 0 K peptide kras-g12v nonamer peptide NA MH1 I J 65.231 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 05/01/24 Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Zhang, M.Y., Luo, L.J., Xu, W., Guan, F.H., Wang, X.Y., Zhu, P., Zhang, J.H., Zhou, X.Y., Wang, F., Ye, S. 2.36 X-RAY DIFFRACTION 0.235 0.190 True 7ams B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 04/20/22 Crystal structure of the complex of the KFN mutant of HuJovi-1 Fab with human TRBC2 homo sapiens homo sapiens Ferrari, M., Bulek, A., Bughda, R., Jha, R., Welin, M., Svensson, A., Logan, D.T., Sewell, A., Onuoha, S., Pule, M. 2.419 X-RAY DIFFRACTION 0.225 0.180 True 7ndt J I NA NA abTCR 0 H peptide unknown NA MH1 F G 38.735 TRBV14 TRAV26 NA NA IMMUNE SYSTEM 01/08/09 UL40:01 TCR in complex with HLA-E with a non-natural amino acid Pengelly, R.J., Robinson, R.A. 2.999 X-RAY DIFFRACTION 0.269 0.221 False 6mra B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV4 NA NA IMMUNE SYSTEM 09/18/19 Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies mus musculus mus musculus Sundararaj, S., Le Nours, J., Praveena, T., Rossjohn, J. 1.7 X-RAY DIFFRACTION 0.219 0.181 True 5swz O N NA NA abTCR 0 M peptide influenza np366 epitope NA MH1 K L 54.186 TRBV17 TRAV14 NA NA IMMUNE SYSTEM 10/05/16 Crystal Structure of NP1-B17 TCR-H2Db-NP complex mus musculus mus musculus unidentified influenza virus mus musculus mus musculus Gras, S., Del Campo, C.M., Farenc, C., Josephs, T.M., Rossjohn, J. 2.65 X-RAY DIFFRACTION 0.249 0.226 True 5nmf J I NA NA abTCR 0 H peptide gag protein NA MH1 F G 53.074 TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR in complex with HLA A02 presenting SLYNTIATL homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.89 X-RAY DIFFRACTION 0.255 0.193 True 8gvi B A NA NA abTCR 0 P peptide 8-mer peptide from protein nef NA MH1 H L 55.872 TRBV7 TRAV8 NA NA IMMUNE SYSTEM 10/19/22 The complex between H25-11 TCR and HLA-A24 bound to HIV-1 Nef138-8 peptide homo sapiens homo sapiens hiv whole-genome vector aa1305#18 homo sapiens homo sapiens Gao, G.F., Shi, Y., Tan, S., Ma, K., Chai, Y., Qi, J., Kawana-Tachikawa, A., Iwamoto, A., Dong, T., Guan, J. 3.3 X-RAY DIFFRACTION 0.314 0.287 True 7n5c E D NA NA abTCR 0 C peptide peptide from polymerase acidic protein NA MH1 A B 43.558 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 07/20/22 6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond mus musculus, homo sapiens mus musculus, homo sapiens influenza a virus mus musculus homo sapiens Szeto, C., Gras, S. 1.87 X-RAY DIFFRACTION 0.233 0.204 True 7rm4 N O NA NA abTCR 0 M peptide cellular tumor antigen p53 peptide NA MH1 K L 37.158 TRBV11 TRAV6 NA NA IMMUNE SYSTEM 02/09/22 Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 3.33 X-RAY DIFFRACTION 0.295 0.237 True 3q5y D NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV12 NA NA NA IMMUNE SYSTEM 03/09/11 V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures mus musculus Chen, Q., Zhang, H., Wang, J.-H. 1.9 X-RAY DIFFRACTION 0.218 0.178 True 8trr J I NA NA abTCR 0 H peptide vimentin NA MH2 F G 38.524 TRBV13 TRAV6 NA NA IMMUNE SYSTEM 07/31/24 T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 mus musculus mus musculus homo sapiens homo sapiens homo sapiens Loh, T.J., Lim, J.J., Reid, H.H., Rossjohn, J. 2.65 X-RAY DIFFRACTION 0.244 0.209 True 3vxt B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV27 TRAV12 NA NA IMMUNE SYSTEM 10/23/13 T36-5 TCR specific for HLA-A24-Nef134-10 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.5 X-RAY DIFFRACTION 0.271 0.230 True 4ozg H G NA NA abTCR 0 J peptide deamidated gliadin-alpha2 peptide NA MH2 A B 35.590 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/16/14 D2 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 3 X-RAY DIFFRACTION 0.241 0.203 True 3pqy J I NA NA abTCR 0 H peptide 10-mer peptide from rna-directed rna polymerase NA MH1 F G 48.235 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 05/18/11 Crystal Structure of 6218 TCR in complex with the H2Db-PA224 mus musculus, homo sapiens mus musculus, homo sapiens synthetic construct mus musculus mus musculus Gras, S., Guillonneau, C., Turner, S.J., Rossjohn, J. 3.192 X-RAY DIFFRACTION 0.316 0.246 True 4ozh H G NA NA abTCR 0 J peptide gliadin-alpha2 peptide NA GA A NA nan TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/16/14 S16 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.243 0.226 True 6cwb D C NA NA abTCR 0 A Hapten (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-[(1E)-4-phenylbutylidene]-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name) FJJ CD1 A B 26.271 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/03/19 Structure of alpha-GSA[8,4P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.85 X-RAY DIFFRACTION 0.275 0.215 True 1hxm NA NA A B gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV9 TRDV2 IMMUNE SYSTEM 06/20/01 Crystal Structure of a Human Vgamma9/Vdelta2 T Cell Receptor homo sapiens homo sapiens Allison, T.J., Winter, C.C., Fournie, J.J., Bonneville, M., Garboczi, D.N. 3.12 X-RAY DIFFRACTION 0.266 0.219 True 2ol3 B A NA NA abTCR 0 P peptide naturally processed octapeptide pbm8 NA MH1 H L 42.309 TRBV1 TRAV16 NA NA IMMUNE SYSTEM 04/03/07 crystal structure of BM3.3 ScFV TCR in complex with PBM8-H-2KBM8 MHC class I molecule mus musculus mus musculus mus musculus mus musculus Mazza, C., Auphan-Anezin, N., Gregoire, C., Guimezanes, A., Kellenberger, C., Roussel, A., Kearney, A., Van der Merwe, P.A., Schmitt-Verhulst, A.M., Malissen, B. 2.9 X-RAY DIFFRACTION 0.284 0.224 True 6fr3 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV21 NA NA IMMUNE SYSTEM 04/18/18 003 TCR Study of CDR Loop Flexibility homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.35 X-RAY DIFFRACTION 0.197 0.165 True 2apt B NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2 X-RAY DIFFRACTION 0.210 0.175 True 7qpj B A NA NA abTCR 0 E peptide melanoma-associated antigen 10 NA MH1 C D 32.147 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 08/03/22 Crystal structure of engineered TCR (756) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Simister, P.C., Border, E.C., Vieira, J.F., Pumphrey, N.J. 1.54 X-RAY DIFFRACTION 0.236 0.202 True 3vxm E D NA NA abTCR 0 C peptide 10-mer peptide from protein nef NA MH1 A B 49.624 TRBV4 TRAV8 NA NA IMMUNE SYSTEM 10/23/13 The complex between C1-28 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.5 X-RAY DIFFRACTION 0.267 0.209 True 6pvd H G NA NA abTCR 0 A Hapten methyl N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alaninate N18 MR1 A B 59.985 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/01/20 Structure of human MAIT A-F7 TCR in complex with human MR1-NV18.1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 2.14 X-RAY DIFFRACTION 0.198 0.168 True 3vxq E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV21 NA NA IMMUNE SYSTEM 10/23/13 H27-14 TCR specific for HLA-A24-Nef134-10 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2 X-RAY DIFFRACTION 0.267 0.222 True 4x6c F E NA NA abTCR 0 C Hapten (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide 42H CD1 C D 80.827 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/28/15 CD1a ternary complex with lysophosphatidylcholine and BK6 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.236 0.176 True 3owe C NA NA NA NA 0 P protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 7byd E D NA NA abTCR 0 C peptide gly-gly-ala-ile NA MH1 A B 37.429 TRBV3 TRAV4 NA NA IMMUNE SYSTEM 03/31/21 Crystal structure of SN45 TCR in complex with lipopeptide-bound Mamu-B*05104 macaca mulatta macaca mulatta simian immunodeficiency virus macaca mulatta macaca mulatta Morita, D., Sugita, M., Iwashita, C. 2.80003 X-RAY DIFFRACTION 0.250 0.185 True 6c09 D C NA NA abTCR 0 A Hapten DECANE D10 CD1 A B 40.347 TRBV7 TRAV29 NA NA IMMUNE SYSTEM 03/21/18 Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wun, K.S., Rossjohn, J. 2.95 X-RAY DIFFRACTION 0.208 0.174 True 5u1r G B NA NA abTCR 0 A Hapten 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID DIF MR1 A H 58.636 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 03/15/17 Structure of human MR1-diclofenac in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.238 0.187 True 6eqa E D NA NA abTCR 0 C peptide ala-ala-gly-ile-gly-ile-leu-thr-val NA MH1 A B 48.740 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 10/10/18 HLA class I histocompatibility antigen homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 3.16 X-RAY DIFFRACTION 0.263 0.186 True 2aq1 C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.1 X-RAY DIFFRACTION 0.243 0.185 True 2cde B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA CELL RECEPTOR 03/07/06 Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR homo sapiens homo sapiens Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y. 3.5 X-RAY DIFFRACTION 0.3504 0.2830 True 2ypl E D NA NA abTCR 0 C peptide kf11 p24 gag peptide NA MH1 A B 27.481 TRBV19 TRAV5 NA NA IMMUNE SYSTEM/VIRAL PROTEIN 11/28/12 Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms homo sapiens homo sapiens human immunodeficiency virus homo sapiens homo sapiens Stewart-Jones, G.B., Simpson, P., van der Merwe, P.A., Easterbrook, P., McMichael, A.J., Rowland-Jones, S.L., Jones, E.Y., Gillespie, G.M. 2.4 X-RAY DIFFRACTION 0.27746 0.22072 True 3sjv J I NA NA abTCR 0 H peptide epstein-barr nuclear antigen 3 NA MH1 F G 37.784 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR in complex with HLA-B8-FLR homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.321 0.253 True 6dfx H G NA NA abTCR 0 NA NA NA NA MH2 A B 35.313 TRBV5 TRAV17 NA NA IMMUNE SYSTEM 04/17/19 human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide homo sapiens homo sapiens homo sapiens homo sapiens Wang, Y., Dai, S. 2.03 X-RAY DIFFRACTION 0.217 0.181 True 6dfq H G NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV1 TRAV10 NA NA IMMUNE SYSTEM 04/17/19 mouse diabetogenic TCR I.29 mus musculus mus musculus Wang, Y., Dai, S. 2.6 X-RAY DIFFRACTION 0.253 0.220 True 7rk7 E D NA NA abTCR 0 C peptide tyrosinase peptide NA MH1 A B 81.339 TRBV10 TRAV4 NA NA IMMUNE SYSTEM 11/02/22 The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Singh, N.K., Davancaze, L.M., Arbuiso, A., Weiss, L.I., Keller, G.L.J., Baker, B.M. 2.54 X-RAY DIFFRACTION 0.255 0.211 True 4apq D C NA NA abTCR 0 A Hapten (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE CIS CD1 A B 24.615 TRBV19 TRAV11 NA NA IMMUNE SYSTEM 04/24/13 Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-sulfatide mus musculus mus musculus mus musculus mus musculus mus musculus Clarke, A.J., Le Nours, J., Rossjohn, J. 3 X-RAY DIFFRACTION 0.232 0.178 True 8wte B A NA NA abTCR 0 J peptide kras-g12v nonamer peptide NA MH1 H I 63.083 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 05/01/24 Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Zhang, M.Y., Luo, L.J., Xu, W., Guan, F.H., Wang, X.Y., Zhu, P., Zhang, J.H., Zhou, X.Y., Wang, F., Ye, S. 2.17 X-RAY DIFFRACTION 0.216 0.171 True 2ial D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 1.92 X-RAY DIFFRACTION 0.265 0.208 True 3uts E D NA NA abTCR 0 C peptide insulin NA MH1 A B 36.754 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 01/25/12 1E6-A*0201-ALWGPDPAAA Complex, Monoclinic homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M. 2.712 X-RAY DIFFRACTION 0.269 0.201 True 4nqd E D NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C F 61.578 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TCR-MR1 ternary complex and non-covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.227 0.181 True 4x6d F E NA NA abTCR 0 J carbohydrate N-ACETYL-D-GLUCOSAMINE NAG CD1 C NA 81.209 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/28/15 CD1a ternary complex with endogenous lipids and BK6 TCR homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.98 X-RAY DIFFRACTION 0.229 0.177 True 6xqp F E NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 51.038 TRBV29 TRAV12 NA NA IMMUNE SYSTEM 08/26/20 Structure of human D462-E4 TCR in complex with human MR1-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.235 0.190 True 3c5z B A NA NA abTCR 0 NA NA NA NA MH2 C D 42.660 TRBV13 TRAV6 NA NA SUGAR BINDING PROTEIN/IMMUNE SYSTEM 04/29/08 Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506 mus musculus mus musculus mus musculus mus musculus Dai, S., Kappler, J. 2.55 X-RAY DIFFRACTION 0.281 0.246 True 3mff D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV14 NA NA IMMUNE SYSTEM 06/02/10 1F1E8hu TCR homo sapiens homo sapiens van Boxel, G.I., Holmes, S., Fugger, L., Jones, E.Y. 2 X-RAY DIFFRACTION 0.243 0.200 True 4p5t F E NA NA abTCR 0 NA NA NA NA MH2 G H 45.696 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 05/28/14 14.C6 TCR complexed with MHC class II I-Ab/3K peptide homo sapiens homo sapiens mus musculus mus musculus Trenh, P., Stadinski, B., Huseby, E.S., Stern, L.J. 3.263 X-RAY DIFFRACTION 0.236 0.186 True 7pdx D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 Crystal structure of parent MAGE-A10 TCR (728) Simister, P.C., Border, E.C., Vieira, J.F., Pumphrey, N.J. 2.27 X-RAY DIFFRACTION 0.252 0.192 False 3qjh B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 The crystal structure of the 5c.c7 TCR mus musculus mus musculus Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 1.9 X-RAY DIFFRACTION 0.256 0.225 True 1qsf E D NA NA abTCR 0 C peptide tax peptide y8a NA MH1 A B 35.353 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 12/21/99 STRUCTURE OF A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE Y8A homo sapiens homo sapiens homo sapiens homo sapiens Ding, Y.H., Baker, B.M., Garboczi, D.N., Biddison, W.E., Wiley, D.C. 2.8 X-RAY DIFFRACTION 0.286 0.245 True 4mji E D NA NA abTCR 0 C peptide hiv reverse transcriptase peptide marker NA MH1 A B 44.030 TRBV7 TRAV17 NA NA IMMUNE SYSTEM 05/28/14 T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01 homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Motozono, C., Takiguchi, M. 2.99 X-RAY DIFFRACTION 0.304 0.242 True 8i5c n m NA NA abTCR 0 l peptide unknown NA MH1 j k 46.886 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 False 6mj6 D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-({4-O-[(4-chlorophenyl)methyl]-alpha-D-galactopyranosyl}oxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanamide JTM CD1 A B 25.995 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxx (JJ166) /iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2.45 X-RAY DIFFRACTION 0.234 0.189 True 1oga E D NA NA abTCR 0 C peptide gilgfvftl NA MH1 A B 62.558 TRBV19 TRAV27 NA NA IMMUNE SYSTEM/RECEPTOR 06/19/03 A structural basis for immunodominant human T-cell receptor recognition. homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Stewart-Jones, G.B.E., McMichael, A.J., Bell, J.I., Stuart, D.I., Jones, E.Y. 1.4 X-RAY DIFFRACTION 0.231 0.218 True 5u16 F E NA NA abTCR 0 C Hapten 2-HYDROXYNAPHTHALENE-1-CARBALDEHYDE 7WO MR1 C D 59.519 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/15/17 Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.219 0.173 True 2gj6 E D NA NA abTCR 0 C | C peptide | Hapten modified htlv-1 tax (y5k-iba) peptide, chain c | 3-INDOLEBUTYRIC ACID NA | 3IB MH1 A B 36.064 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 10/03/06 The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide homo sapiens homo sapiens | homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.56 X-RAY DIFFRACTION 0.250 0.199 True 6cx5 D C NA NA abTCR 0 A Hapten (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(8-phenyloctyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name) FJM CD1 A B 26.223 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/10/19 Structure of alpha-GSA[8,8P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.4 X-RAY DIFFRACTION 0.258 0.214 True 7n2q F D NA NA abTCR 0 C peptide yeih protein NA MH1 A B 22.171 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 AS4.3-YEIH-HLA*B27 homo sapiens homo sapiens escherichia coli homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.7 X-RAY DIFFRACTION 0.264 0.213 True 4pjg F E NA NA abTCR 0 C Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 C D 60.316 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-F3-C1 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.213 0.167 True 5e6i L F NA NA abTCR 0 O peptide matrix protein 1 NA MH1 M N 63.111 TRBV27 TRAV35 NA NA IMMUNE SYSTEM 10/19/16 Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Gao, M., Mariuzza, R. 4 X-RAY DIFFRACTION 0.338 0.259 True 3qdg E D NA NA abTCR 0 C peptide mart-1 (26-35) peptide NA MH1 A B 34.175 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/06/11 The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.69 X-RAY DIFFRACTION 0.278 0.218 True 6vma E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV19 TRAV12 NA NA IMMUNE SYSTEM 01/20/21 T4H2 T cell receptor bound to HLA-A2 presenting gp100 peptide (ITDQVPFSV) homo sapiens homo sapiens Smith, A.R., Baker, B.M. 2.75 X-RAY DIFFRACTION 0.219 0.177 True 5xot E NA NA NA NA 0 D | C protein | peptide the delta chain of tu55 tcr | an hiv reverse transcriptase epitope NA | NA MH1 A B nan TRBV6 NA NA NA IMMUNE SYSTEM 06/14/17 Crystal structure of pHLA-B35 in complex with TU55 T cell receptor homo sapiens homo sapiens | human immunodeficiency virus 1 homo sapiens homo sapiens Shi, Y., Qi, J., Gao, G.F. 2.787 X-RAY DIFFRACTION 0.254 0.199 True 2vlr E D NA NA abTCR 0 C peptide flu matrix peptide NA MH1 A B 61.224 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 01/22/08 The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain homo sapiens homo sapiens unidentified influenza virus homo sapiens homo sapiens Ishizuka, J., Stewart-Jones, G., van der Merwe, A., Bell, J., McMichael, A., Jones, Y. 2.3 X-RAY DIFFRACTION 0.281 0.219 True 6mno B A NA NA abTCR 0 NA NA NA NA MH2 C D 43.870 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/03/19 6235 TCR bound to I-Ab Padi4 mus musculus mus musculus mus musculus mus musculus Stadinski, B.D., Blevins, S.J., Huseby, E.S. 2.9 X-RAY DIFFRACTION 0.270 0.215 True 5d7k E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV36 NA NA IMMUNE SYSTEM 01/27/16 Structure of MR1-reactive MAV36 TCR homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.202 0.166 True 3skn B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR unliganded homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.292 0.194 True 7na5 E D NA NA abTCR 0 C peptide heat shock factor protein 2 NA MH1 A B 57.448 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 06/22/22 Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen mus musculus mus musculus mus musculus mus musculus homo sapiens Patskovsky, Y., Finnigan, J., Patskovska, L., Newman, J., Bhardwaj, N., Krogsgaard, M. 2.5 X-RAY DIFFRACTION 0.249 0.184 True 5c07 J I NA NA abTCR 0 H peptide marker peptide NA MH1 F G 43.963 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.11 X-RAY DIFFRACTION 0.237 0.191 True 5d7j B A NA NA abTCR 0 E Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 E F 60.918 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-5-OP-RU in complex with human MAIT M33.64(Y95alphaF) TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Woolley, R.E., Rossjohn, J. 1.97 X-RAY DIFFRACTION 0.222 0.179 True 3o6f D C NA NA abTCR 0 NA NA NA NA MH2 A B 35.816 TRBV20 TRAV26 NA NA IMMUNE SYSTEM 03/02/11 Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4 homo sapiens homo sapiens homo sapiens homo sapiens Yin, Y., Li, Y., Martin, R., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.279 0.239 True 5u72 E D NA NA abTCR 0 C Hapten 5-HYDROXYDICLOFENAC 7ZV MR1 C F 58.430 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-5OH-DCF in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.231 0.173 True 8cx4 F D NA NA abTCR 0 C peptide yeih NA MH1 A B 21.114 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 TCR-antigen complex AS8.4-YEIH-HLA*B27 homo sapiens homo sapiens escherichia coli homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.2 X-RAY DIFFRACTION 0.264 0.220 True 4pri E D NA NA abTCR 0 C peptide epstein-barr nuclear antigen 1 NA MH1 A B 42.699 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TK3 TCR-HLA-B*35:08-HPVG complex homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Yu Chih, L., Rossjohn, J., Gras, S. 2.4 X-RAY DIFFRACTION 0.261 0.213 True 8ye4 H G NA NA abTCR 0 E peptide spike protein s1 NA MH1 A B 52.907 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 08/21/24 The complex of TCR NYN-I and HLA-A24 bound to SARS-CoV-2 Spike448-456 peptide NYNYLYRLF homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Deng, S.S., Jin, T.C., Xu, Z.H., Wang, M.H. 3.2 X-RAY DIFFRACTION 0.310 0.266 True 3r8b J NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 3t0e D C NA NA abTCR 0 NA NA NA NA MH2 A B 36.894 TRBV20 TRAV26 NA NA IMMUNE SYSTEM 03/07/12 Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4 homo sapiens homo sapiens homo sapiens homo sapiens Yin, Y., Mariuzza, R.A. 4 X-RAY DIFFRACTION 0.305 0.238 True 5m02 H G NA NA abTCR 0 P peptide lcmv-derived gp33 altered peptide ligand pf NA MH1 A B 41.995 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 12/20/17 Crystal structure of murine P14 TCR / H-2Db with PF, modified gp33 peptide from LCMV mus musculus mus musculus lymphocytic choriomeningitis virus mus musculus mus musculus Achour, A., Sandalova, T., Sun, R. 1.75 X-RAY DIFFRACTION 0.214 0.188 True 4pji H G NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 60.834 TRBV6 TRAV1 NA NA Immune System 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT C-C10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.228 0.188 True 3axl B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV13 NA NA IMMUNE SYSTEM 08/03/11 Murine Valpha 10 Vbeta 8.1 T-cell receptor mus musculus mus musculus Patel, O., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.327 0.254 True 5d2l P O NA NA abTCR 0 T peptide asn-leu-val-pro-met-val-ala-thr-val NA MH1 M N 28.353 TRBV7 TRAV24 NA NA IMMUNE SYSTEM 10/07/15 Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2 homo sapiens homo sapiens cytomegalovirus homo sapiens homo sapiens Gao, M., Mariuzza, R.A. 3.511 X-RAY DIFFRACTION 0.355 0.270 True 2ckb D C NA NA abTCR 0 Q peptide dev8 peptide NA MH1 I M 21.479 TRBV13 TRAV9 NA NA MAJOR HISTOCOMPATIBILITY COMPLEX 04/29/98 STRUCTURE OF THE 2C/KB/DEV8 COMPLEX mus musculus mus musculus mus musculus mus musculus Garcia, K.C., Degano, M., Wilson, I.A. 3 X-RAY DIFFRACTION 0.322 0.221 True 3tfk D C NA NA abTCR 0 B peptide p4b10 peptide NA MH1 A NA 45.572 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3-p4B10/H2-Ld mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 2.753 X-RAY DIFFRACTION 0.291 0.247 True 7n2s F D NA NA abTCR 0 C peptide pre-mrna processing factor 3 NA MH1 A B 22.499 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 AS3.1-PRPF3-HLA*B27 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.37 X-RAY DIFFRACTION 0.311 0.251 True 5nmd D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR Specific for HLA A02 presenting HIV Epitope SLYNTVATL homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.07 X-RAY DIFFRACTION 0.223 0.189 True 5ksb H G NA NA abTCR 0 J peptide dq8.5-glia-gamma1 peptide NA MH2 A B 33.345 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 09/21/16 T15-DQ8.5-glia-gamma1 complex homo sapiens homo sapiens triticum aestivum homo sapiens triticum aestivum, homo sapiens Petersen, J., Rossjohn, J., Reid, H.H. 2.9 X-RAY DIFFRACTION 0.254 0.219 True 7zt8 E D NA NA abTCR 0 NA NA NA NA MR1 A B 60.370 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex in human MR1 bound to 3FBA homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Srikannathasan, V., Robinson, R.A. 2.29 X-RAY DIFFRACTION 0.263 0.211 True 4e41 J I NA NA abTCR 0 H peptide triosephosphate isomerase NA MH2 F G 45.682 TRBV5 TRAV22 NA NA IMMUNE SYSTEM 08/29/12 Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A. 2.6 X-RAY DIFFRACTION 0.264 0.197 True 3are D C NA NA abTCR 0 A Hapten N-{(2S,3R)-1-[(4-DEOXY-ALPHA-D-XYLO-HEXOPYRANOSYL)OXY]-3-HYDROXYOCTADECAN-2-YL}HEXACOSANAMIDE 4GH CD1 A B 23.713 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 03/30/11 Ternary crystal structure of the mouse NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wun, K.S., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.279 0.220 True 3axl H G NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV13 NA NA IMMUNE SYSTEM 08/03/11 Murine Valpha 10 Vbeta 8.1 T-cell receptor mus musculus mus musculus Patel, O., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.327 0.254 True 3mfg B NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV20 NA NA NA TOXIN/IMMUNE SYSTEM 11/24/10 Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T cell receptor beta chain Vbeta2.1 (EP-8) homo sapiens Bonsor, D.A., Sundberg, E.J. 2.37 X-RAY DIFFRACTION 0.283 0.234 True 8d5p B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV1 TRAV6 NA NA IMMUNE SYSTEM 09/14/22 Mouse TCR TG6 mus musculus mus musculus Wang, Y., Dai, S. 2.75 X-RAY DIFFRACTION 0.301 0.224 True 2uwe F E NA NA abTCR 0 C peptide uncharacterized protein c15orf24 NA MH1 A B 68.542 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 09/25/07 Large CDR3a loop alteration as a function of MHC mutation mus musculus mus musculus homo sapiens homo sapiens homo sapiens Miller, P.J., Pazy, Y., Conti, B., Riddle, D., Biddison, W.E., Appella, E., Collins, E.J. 2.4 X-RAY DIFFRACTION 0.290 0.240 True 7q9a E D NA NA abTCR 0 C peptide leu-leu-leu-gly-ile-gly-ile-leu-val-leu NA MH1 A B 48.391 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 02/22/23 MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Wall, A., Fuller, A. 2.1 X-RAY DIFFRACTION 0.243 0.205 True 4l4v H G NA NA abTCR 0 A Hapten 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol 1VY MR1 A B 60.071 TRBV6 TRAV1 NA NA Membrane Protein/Immune System 07/17/13 Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S.B.G., Birkinshaw, R.W., Beddoe, T., Corbett, A.J., Liu, L., Miles, J.J., Meehan, B., Reantragoon, R., Sandoval-Romero, M.L., Sullivan, L.C., Brooks, A.G., Chen, Z., Fairlie, D.P., McCluskey, J., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.209 0.178 True 3r8b D NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 5c08 E D NA NA abTCR 0 C peptide marker peptide NA MH1 A B 44.155 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in Complex with HLA-A0e carrying RQWGPDPAAV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.332 X-RAY DIFFRACTION 0.272 0.206 True 3hg1 E D NA NA abTCR 0 C peptide cancer/mart-1 NA MH1 A B 48.397 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 07/28/09 Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Cole, D.K., Yuan, F., Rizkallah, P.J., Miles, J.J., Gostick, E., Price, D.A., Gao, G.F., Jakobsen, B.K., Sewell, A.K. 3 X-RAY DIFFRACTION 0.304 0.225 False 3tf7 I i NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 QL9/H2-Ld complex mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 2.75 X-RAY DIFFRACTION 0.261 0.237 True 2eyt B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 03/21/06 A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition homo sapiens homo sapiens Kjer-Nielsen, L., Borg, N.A. 2.6 X-RAY DIFFRACTION 0.256 0.207 True 5til L K NA NA abTCR 0 F peptide pre-glycoprotein polyprotein gp complex NA MH1 D E 46.162 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 11/01/17 Murine class I major histocompatibility complex H-2 Db in complex with LCMV-derived GP33 altered peptide V3P and T-cell receptor P14 mus musculus mus musculus lymphocytic choriomeningitis mammarenavirus mus musculus mus musculus Achour, A., Sandalova, T., Allerbring, E.B. 2.83 X-RAY DIFFRACTION 0.275 0.219 True 8i5d B A NA NA abTCR 0 P peptide peptide kras-g12v-9 NA MH1 H L 45.342 TRBV16 TRAV8 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.3 X-RAY DIFFRACTION 0.256 0.236 True 5jhd E D NA NA abTCR 0 C peptide influenza m1(58-66) peptide NA MH1 A B 47.601 TRBV19 TRAV38 NA NA IMMUNE SYSTEM 03/01/17 Crystal structure of LS10-TCR/M1-HLA-A*02 complex homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Stern, L.J., Selin, L.K., Song, I. 2.46 X-RAY DIFFRACTION 0.223 0.204 True 6pum E D NA NA abTCR 0 C Hapten 1,2-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol Q84 MR1 C F 58.412 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-2'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.96 X-RAY DIFFRACTION 0.190 0.154 True 7jwj E D NA NA abTCR 0 C peptide nucleoprotein NA MH1 A B 14.478 TRBV17 TRAV4 NA NA IMMUNE SYSTEM 07/07/21 Crystal Structure of B17-C1 TCR-H2Db mus musculus mus musculus influenza a virus mus musculus mus musculus Farenc, C., Rossjohn, J., Gras, S., Szeto, C. 3.251 X-RAY DIFFRACTION 0.306 0.276 True 3tn0 D C NA NA abTCR 0 A Hapten N-[(3S,4S,5R)-4,5-DIHYDROXY-1-[(2R,3R,4R,5R,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]NONADECAN-3-YL]HEXACOSANAMIDE QUX CD1 A B 24.082 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 12/14/11 Structure of mouse Va14Vb8.2NKT TCR-mouse CD1d-a-C-Galactosylceramide complex homo sapiens, mus musculus homo sapiens, mus musculus mus musculus mus musculus mus musculus Patel, O., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.289 0.225 True 4mnq E D NA NA abTCR 0 C peptide telomerase reverse transcriptase NA MH1 A B 43.052 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 11/13/13 TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions homo sapiens pan troglodytes, homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Jakobsen, B.K. 2.742 X-RAY DIFFRACTION 0.284 0.214 True 6py2 E D NA NA abTCR 0 C peptide dq2.2-glut-l1 NA MH2 A B 53.941 TRBV11 TRAV9 NA NA IMMUNE SYSTEM 01/15/20 HLA-TCR complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Ting, Y.T., Peteren, J., Reid, H.H., Rossjohn, J. 2.82543 X-RAY DIFFRACTION 0.244 0.216 True 4gg8 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV9 TRAV26 NA NA IMMUNE SYSTEM 10/24/12 Immune Receptor homo sapiens homo sapiens Broughton, S.E., Theodossis, A., Petersen, J., Reid, H.H., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.308 0.261 True 7dzn D E NA NA abTCR 0 C peptide gag-pol polyprotein NA MH1 A B 45.412 TRBV12 TRAV26 NA NA IMMUNE SYSTEM 01/26/22 Crystal Structure of the cross-restricted T18A TCR and HLAB4201 bound to HIV-1 Gag TL9 peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Liu, Y., Yin, L. 2.63 X-RAY DIFFRACTION 0.261 0.207 True 8wul H G NA NA abTCR 0 T peptide kras-g12v nonamer peptide NA MH1 R S 65.409 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 05/01/24 Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Zhang, M.Y., Luo, L.J., Xu, W., Guan, F.H., Wang, X.Y., Zhu, P., Zhang, J.H., Zhou, X.Y., Wang, F., Ye, S. 2.36 X-RAY DIFFRACTION 0.235 0.190 True 7ndu E D NA NA abTCR 0 C peptide unknown NA MH1 A B 77.244 TRBV7 TRAV4 NA NA IMMUNE SYSTEM 01/08/09 Gag:02 TCR in complex with HLA-E featuring a non-natural amino acid Pengelly, R.J., Robinson, R.A. 2.9 X-RAY DIFFRACTION 0.302 0.242 False 3vwk D C NA NA abTCR 0 A Hapten N-{(2S,3R)-1-[(4-DEOXY-ALPHA-D-XYLO-HEXOPYRANOSYL)OXY]-3-HYDROXYOCTADECAN-2-YL}HEXACOSANAMIDE 4GH CD1 A B 32.756 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 10/03/12 Ternary crystal structure of the human NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wun, K.S., Rossjohn, J. 2.935 X-RAY DIFFRACTION 0.250 0.191 True 6rpb J I NA NA abTCR 0 H peptide heteroclitic ny-eso-1 157-165 peptide NA MH1 F G 68.179 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 2.5 X-RAY DIFFRACTION 0.273 0.249 True 6mnn B A NA NA abTCR 0 NA NA NA NA MH2 C D 45.543 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/03/19 6236 TCR bound to I-Ab Padi4 mus musculus mus musculus mus musculus mus musculus Blevins, S.J., Stadinski, B.D., Huseby, E.S. 2.83 X-RAY DIFFRACTION 0.262 0.219 True 3byt G NA NA NA NA 0 D protein enterotoxin type c-3 NA NA NA NA nan TRBV13 NA NA NA TOXIN 05/12/09 A complex between a variant of staphylococcal enterotoxin C3 and the variable domain of the murine T cell receptor beta chain 8.2 mus musculus staphylococcus aureus Cho, S., Eric, J.S. 2.3 X-RAY DIFFRACTION 0.278 0.226 True 3sdx F E NA NA abTCR 0 A Hapten N-[(2S,3R)-1-(BETA-D-GALACTOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]TETRACOSANAMIDE GCY CD1 A B 28.603 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 10/05/11 Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Clarke, A.J., Patel, O., Rossjohn, J. 3.12 X-RAY DIFFRACTION 0.273 0.232 True 4eup J I NA NA abTCR 0 C peptide melanoma antigen recognized by t-cells 1 NA MH1 A B 32.071 TRBV28 TRAV12 NA NA IMMUNE SYSTEM 05/01/13 The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Hossain, M., Baker, B.M. 2.88 X-RAY DIFFRACTION 0.295 0.235 True 7n1e E D NA NA abTCR 0 C peptide spike protein s2 NA MH1 A B 35.924 TRBV11 TRAV16 NA NA IMMUNE SYSTEM 07/28/21 SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 binds to RLQ-HLA-A2 homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 2.3 X-RAY DIFFRACTION 0.258 0.212 True 4ei6 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Structure of XV19 Valpha1-Vbeta16 Type-II Natural Killer T cell receptor mus musculus, homo sapiens mus musculus, homo sapiens Patel, O., Rossjohn, J. 1.6 X-RAY DIFFRACTION 0.241 0.208 True 4g8f B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV1 NA NA IMMUNE SYSTEM 05/08/13 Crystal Structure of clone42 TCR homo sapiens homo sapiens Gras, S., Bhati, M., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.236 0.203 True 5u1r E D NA NA abTCR 0 C Hapten 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID DIF MR1 C F 61.153 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 03/15/17 Structure of human MR1-diclofenac in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.238 0.187 True 7fje n m NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/27/22 Cryo-EM structure of a membrane protein(LL) homo sapiens homo sapiens Chen, Y., Zhu, Y., Gao, W., Zhang, A., Guo, C., Huang, Z. 3.0 ELECTRON MICROSCOPY NA NA False 4l9l B A NA NA abTCR 0 NA NA NA NA MR1 C NA 62.511 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 10/16/13 Crystal structure of a human Valpha7.2/Vbeta13.2 MAIT TCR in complex with bovine MR1 homo sapiens homo sapiens bos taurus Lopez-Sagaseta, J., Adams, E.J. 3.4 X-RAY DIFFRACTION 0.312 0.254 True 3qeq E D NA NA abTCR 0 C peptide mart-1(27-35) peptide NA MH1 A B 44.348 TRBV10 TRAV35 NA NA IMMUNE SYSTEM 07/06/11 The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.59 X-RAY DIFFRACTION 0.269 0.215 True 8eo8 O N NA NA abTCR 0 M peptide nucleoprotein np8 epitope NA MH1 K L 42.456 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.3 X-RAY DIFFRACTION 0.219 0.181 True 5c0a J I NA NA abTCR 0 H peptide marker peptide NA MH1 F G 43.870 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying MVW peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.46 X-RAY DIFFRACTION 0.232 0.193 True 2cdg B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV17 NA NA RECEPTOR 03/07/06 Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5B) homo sapiens homo sapiens Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y. 2.6 X-RAY DIFFRACTION 0.318 0.217 True 4grl D C NA NA abTCR 0 NA NA NA NA MH2 A B 26.251 TRBV7 TRAV13 NA NA IMMUNE SYSTEM 11/06/13 Crystal structure of a autoimmune TCR-MHC complex homo sapiens homo sapiens homo sapiens homo sapiens Sethi, D.K., Wucherpfennig, K.W. 2.86 X-RAY DIFFRACTION 0.256 0.202 True 3mff B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV14 NA NA IMMUNE SYSTEM 06/02/10 1F1E8hu TCR homo sapiens homo sapiens van Boxel, G.I., Holmes, S., Fugger, L., Jones, E.Y. 2 X-RAY DIFFRACTION 0.243 0.200 True 3of6 B NA NA NA NA 0 F protein pre t-cell antigen receptor alpha NA NA NA NA nan TRBV7 NA NA NA IMMUNE SYSTEM 10/20/10 Human pre-T cell receptor crystal structure homo sapiens homo sapiens Pang, S.S. 2.8 X-RAY DIFFRACTION 0.240 0.175 True 2ian O N NA NA abTCR 0 M peptide 15-mer peptide from triosephosphate isomerase NA MH2 K L 42.038 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.296 0.221 True 6cuh B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV9 NA NA IMMUNE SYSTEM 01/16/19 Crystal structure of the unliganded BC8B TCR homo sapiens homo sapiens Shahine, A.E., Rossjohn, J. 2.01 X-RAY DIFFRACTION 0.232 0.208 True 4e42 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV22 NA NA IMMUNE SYSTEM 08/29/12 Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 homo sapiens homo sapiens Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A. 2.7 X-RAY DIFFRACTION 0.263 0.200 True 5tje H G NA NA abTCR 0 I peptide peptide gp33-41 from lcmv NA MH1 A B 44.761 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 11/01/17 Murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 and T cell receptor P14 mus musculus mus musculus lymphocytic choriomeningitis virus mus musculus mus musculus Achour, A., Sandalova, T., Allerbring, E., Popov, A. 3.2 X-RAY DIFFRACTION 0.314 0.228 True 6cxa D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-8-oxo-8-[(6-phenylhexyl)amino]-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octan-2-yl]icosanamide EMG CD1 A B 25.876 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/10/19 Structure of alpha-GSA[20,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.65 X-RAY DIFFRACTION 0.253 0.195 True 3e3q W V NA NA abTCR 0 X peptide ql9 peptide NA MH1 U NA 42.607 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 7sg0 E D NA NA abTCR 0 C peptide dq2-glia-omega1 peptide NA GB B NA nan TRBV7 TRAV9 NA NA IMMUNE SYSTEM 02/23/22 W316 TCR in complex with HLA-DQ2-omega1 homo sapiens homo sapiens homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3 X-RAY DIFFRACTION 0.230 0.191 True 3skn F E NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR unliganded homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.292 0.194 True 5w1w E D NA NA abTCR 0 C peptide leader peptide of hla class i histocompatibility antigen, aalpha chain NA MH1 A B 67.933 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.263 0.215 True 6pul E D NA NA abTCR 0 C Hapten 1,3-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol Q81 MR1 C F 58.221 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1 3'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.84 X-RAY DIFFRACTION 0.184 0.156 True 2vlj E D NA NA abTCR 0 C peptide flu matrix peptide NA MH1 A B 61.297 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 01/22/08 The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain homo sapiens homo sapiens unidentified influenza virus homo sapiens homo sapiens Ishizuka, J., Stewart-Jones, G., Van Der Merwe, A., Bell, J., Mcmichael, A., Jones, Y. 2.4 X-RAY DIFFRACTION 0.272 0.196 True 5vcj D C NA NA abTCR 0 A Hapten (2S,3S,4R)-2-amino-3,4-dihydroxyoctadecyl alpha-D-galactopyranoside N57 CD1 A B 25.967 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/04/18 Structure of alpha-galactosylphytosphingosine bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wang, J., Zajonc, D.M. 3.16 X-RAY DIFFRACTION 0.249 0.189 True 6cqn E D NA NA abTCR 0 C peptide peptide from capsid protein p24 NA MH2 A B 32.805 TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of F5 TCR -DR11-RQ13 peptide complex homo sapiens homo sapiens hiv-1 m homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.251 0.196 True 3vxr E D NA NA abTCR 0 C peptide 10-mer peptide from protein nef NA MH1 A B 51.107 TRBV7 TRAV21 NA NA IMMUNE SYSTEM 10/23/13 The complex between H27-14 TCR and HLA-A24 bound to HIV-1 Nef134-10(wt) peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.4 X-RAY DIFFRACTION 0.242 0.199 True 7zt4 E D NA NA abTCR 0 NA NA NA NA MR1 A B 60.705 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex with human MR1 bound to 6FP homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Robinson, R.A. 2.02 X-RAY DIFFRACTION 0.268 0.234 True 5wki E D NA NA abTCR 0 D Hapten (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate D3D CD1 A B 69.353 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 11/01/17 Crystal structure of PG90 TCR-CD1b-PG complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Shahine, A., Gras, S., Rossjohn, J. 2.75 X-RAY DIFFRACTION 0.252 0.212 True 5ks9 F E NA NA abTCR 0 I peptide dq8-glia-alpha1 peptide NA MH2 C D 38.976 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 09/21/16 Bel502-DQ8-glia-alpha1 complex homo sapiens homo sapiens triticum aestivum homo sapiens triticum aestivum, homo sapiens Petersen, J., Rossjohn, J., Reid, H.H. 2.55 X-RAY DIFFRACTION 0.224 0.199 True 6vmc E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV19 TRAV12 NA NA IMMUNE SYSTEM 01/20/21 T4H2 T cell receptor bound to HLA-A2 presenting gp100T2L peptide (ILDQVPFSV) homo sapiens homo sapiens Smith, A.R., Baker, B.M. 2.85 X-RAY DIFFRACTION 0.239 0.197 True 3skn D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR unliganded homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.292 0.194 True 4eup H G NA NA abTCR 0 F peptide melanoma antigen recognized by t-cells 1 NA MH1 D E 31.751 TRBV28 TRAV12 NA NA IMMUNE SYSTEM 05/01/13 The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Hossain, M., Baker, B.M. 2.88 X-RAY DIFFRACTION 0.295 0.235 True 7nmg E D NA NA abTCR 0 C peptide diabetes epitope lwmrllpll NA MH1 A B 35.132 TRBV7 TRAV5 NA NA IMMUNE SYSTEM 09/07/22 Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Cole, D.K., Wall, A. 2.48 X-RAY DIFFRACTION 0.271 0.198 True 3d3v E D NA NA abTCR 0 C peptide modified htlv-1 tax (y5(3,4-difluoro)f) peptide NA MH1 A B 35.930 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 06/16/09 The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Clemens, J.R., Baker, B.M. 2.8 X-RAY DIFFRACTION 0.278 0.220 True 6frb B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.75 X-RAY DIFFRACTION 0.243 0.210 True 6fur D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.73 X-RAY DIFFRACTION 0.226 0.189 True 3kxf P N NA NA abTCR 0 T peptide peptide from trans-activator protein bzlf1 NA MH1 K L 67.855 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Tynan, F.E., Gras, S., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.291 0.213 True 5isz E D NA NA abTCR 0 C peptide influenza m1 for peptide NA MH1 A B 55.999 TRBV19 TRAV24 NA NA IMMUNE SYSTEM 03/01/17 Crystal structure of LS01-TCR/M1-HLA-A*02 complex homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Stern, L.J., Selin, L.K., Song, I. 2.06 X-RAY DIFFRACTION 0.200 0.184 True 6u3n E D NA NA abTCR 0 C peptide peptide NA MH2 A B 34.230 TRBV5 TRAV8 NA NA IMMUNE SYSTEM 12/18/19 LS2.8/3.15 - DQ2-P.fluor-alpha1a complex homo sapiens homo sapiens pseudomonas fluorescens homo sapiens homo sapiens Petersen, J., Rossjohn, J. 2.8 X-RAY DIFFRACTION unknown unknown True 1bwm A a NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/22/99 A SINGLE-CHAIN T CELL RECEPTOR mus musculus Hare, B.J., Wyss, D.F., Reinherz, E.L., Wagner, G. NOT SOLUTION NMR NA NA True 7q9b J I NA NA abTCR 0 H peptide unknown NA MH1 F G 47.167 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR Rizkallah, P.J., Sewell, A.K., Wall, A., Fuller, A. 3.24 X-RAY DIFFRACTION 0.277 0.226 False 2vlr J I NA NA abTCR 0 H peptide flu matrix peptide NA MH1 F G 61.782 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 01/22/08 The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain homo sapiens homo sapiens unidentified influenza virus homo sapiens homo sapiens Ishizuka, J., Stewart-Jones, G., van der Merwe, A., Bell, J., McMichael, A., Jones, Y. 2.3 X-RAY DIFFRACTION 0.281 0.219 True 8enh E D NA NA abTCR 0 C peptide nucleoprotein np7 epitope NA MH1 A B 40.940 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain homo sapiens homo sapiens influenza a virus (strain a/2002/h3n2) homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.50003 X-RAY DIFFRACTION 0.230 0.191 True 2f54 L K NA NA abTCR 0 H peptide cancer/testis antigen 1b NA MH1 F G 71.198 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 04/25/06 Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Jakobsen, B.K., Dunn, S.M., Sami, M. 2.7 X-RAY DIFFRACTION 0.286 0.221 True 6rsy E D NA NA abTCR 0 C peptide arg-met-phe-pro-asn-ala-pro-tyr-leu NA MH1 A B 52.640 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/15/20 The complex between TCR a7b2 and human Class I MHC HLA-A0201-WT1 with the bound RMFPNAPYL peptide. homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Srikannathasan, V., Robinson, R.A. 2.95 X-RAY DIFFRACTION 0.291 0.251 True 4mvb D C NA NA abTCR 0 B peptide pcpb7 NA MH1 A NA 58.425 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 08/19/15 42F3 pCPB7/H-2Ld Complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 3.088 X-RAY DIFFRACTION 0.279 0.231 True 2eyt D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 03/21/06 A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition homo sapiens homo sapiens Kjer-Nielsen, L., Borg, N.A. 2.6 X-RAY DIFFRACTION 0.256 0.207 True 1mi5 E D NA NA abTCR 0 C peptide epstein barr virus peptide NA MH1 A B 42.752 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 02/04/03 The crystal structure of LC13 TcR in complex with HLAB8-EBV peptide complex homo sapiens homo sapiens homo sapiens homo sapiens Kjer-Nielsen, L., Clements, C.S., Purcell, A.W., Brooks, A.G., Whisstock, J.C., Burrows, S.R., McCluskey, J., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.288 0.226 True 6vm9 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV19 TRAV12 NA NA IMMUNE SYSTEM 01/20/21 T4H2 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV) homo sapiens homo sapiens Smith, A.R., Baker, B.M. 2.9 X-RAY DIFFRACTION 0.250 0.210 True 4en3 B A NA NA abTCR 0 C carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 C D 21.296 TRBV25 TRAV17 NA NA IMMUNE SYSTEM 10/31/12 Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Lopez-Sagaseta, J., Adams, E.J. 2.568 X-RAY DIFFRACTION 0.266 0.208 True 1zgl V U NA NA abTCR 0 L peptide myelin basic protein NA MH2 J K 41.475 TRBV5 TRAV9 NA NA IMMUNE SYSTEM 10/18/05 Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Li, Y., Huang, Y., Lue, J., Quandt, J.A., Martin, R., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.329 0.280 True 6cwe D C NA NA abTCR 0 A Hapten (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(6-phenylhexyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide 7LP CD1 A B 25.867 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/03/19 Structure of alpha-GSA[8,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.2 X-RAY DIFFRACTION 0.236 0.204 True 3vxq B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV21 NA NA IMMUNE SYSTEM 10/23/13 H27-14 TCR specific for HLA-A24-Nef134-10 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2 X-RAY DIFFRACTION 0.267 0.222 True 5swz J I NA NA abTCR 0 H peptide influenza np366 epitope NA MH1 F G 52.280 TRBV17 TRAV14 NA NA IMMUNE SYSTEM 10/05/16 Crystal Structure of NP1-B17 TCR-H2Db-NP complex mus musculus mus musculus unidentified influenza virus mus musculus mus musculus Gras, S., Del Campo, C.M., Farenc, C., Josephs, T.M., Rossjohn, J. 2.65 X-RAY DIFFRACTION 0.249 0.226 True 1h5b NA B NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV4 NA NA T CELL RECEPTOR 06/21/01 T cell receptor Valpha11 (AV11S5) domain mus musculus Machius, M., Cianga, P., Deisenhofer, J., Sally Ward, E. 1.85 X-RAY DIFFRACTION 0.245 0.224 True 3vxs E D NA NA abTCR 0 C peptide 10-mer peptide from protein nef NA MH1 A B 53.683 TRBV7 TRAV21 NA NA IMMUNE SYSTEM 10/23/13 The complex between H27-14 TCR and HLA-A24 bound to HIV-1 Nef134-10(6L) peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 1.8 X-RAY DIFFRACTION 0.230 0.201 True 7ow5 E D NA NA abTCR 0 C peptide kras peptide (vvvgaggvgk) NA MH1 A B 49.011 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 07/20/22 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVVGAGGVGK) homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Robinson, R.A. 2.58 X-RAY DIFFRACTION 0.274 0.206 True 2po6 D C NA NA abTCR 0 C carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 A B 31.274 TRBV25 TRAV10 NA NA LIPID BINDING PROTEIN/IMMUNE SYSTEM 07/03/07 Crystal structure of CD1d-lipid-antigen complexed with Beta-2-Microglobulin, NKT15 Alpha-Chain and NKT15 Beta-Chain homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Borg, N.A. 3.2 X-RAY DIFFRACTION 0.293 0.226 True 8gvg B A NA NA abTCR 0 P peptide mutated 8-mer peptide from protein nef NA MH1 H L 55.860 TRBV7 TRAV8 NA NA IMMUNE SYSTEM 10/19/22 The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 (2F) peptide homo sapiens homo sapiens hiv whole-genome vector aa1305#18 homo sapiens homo sapiens Gao, G.F., Shi, Y., Ma, K., Chai, Y., Guan, J., Qi, J., Tan, S., Dong, T., Iwamoto, A., Kawana-Tachikawa, A. 3.37 X-RAY DIFFRACTION 0.320 0.299 True 4x6b D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/28/15 BK6 TCR apo structure homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.229 0.188 True 7ufj F E NA NA abTCR 0 NA NA NA NA MR1 C D 61.813 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 12/14/22 Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens Wang, C.J., Rossjohn, J., Le Nours, J. 2.5 X-RAY DIFFRACTION 0.238 0.181 True 2vlk E D NA NA abTCR 0 C peptide flu matrix peptide NA MH1 A B 62.199 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 01/22/08 The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain homo sapiens homo sapiens unidentified influenza virus homo sapiens homo sapiens Ishizuka, J., Stewart-Jones, G., Van Der Merwe, A., Bell, J., Mcmichael, A., Jones, Y. 2.5 X-RAY DIFFRACTION 0.288 0.218 True 8trl J I NA NA abTCR 0 C peptide alpha-enolase NA MH2 A B 34.816 TRBV2 TRAV26 NA NA IMMUNE SYSTEM 07/31/24 T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Lim, J.J., Loh, T.J., Reid, H.H., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.234 0.210 True 6cx9 D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-8-oxo-8-[(6-phenylhexyl)amino]-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octan-2-yl]hexacosanamide EM4 CD1 A B 25.853 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/10/19 Structure of alpha-GSA[16,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.36 X-RAY DIFFRACTION 0.235 0.192 True 7ndq E D NA NA abTCR 0 C peptide unknown NA MH1 A B 77.515 TRBV7 TRAV4 NA NA IMMUNE SYSTEM 01/08/09 Gag:02 TCR in complex with HLA-E. Pengelly, R.J., Robinson, R.A. 2.551 X-RAY DIFFRACTION 0.296 0.240 False 4pj7 F E NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 61.165 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT TRBV6-4 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.219 0.171 True 4mng NA NA E e gdTCR 0 A Hapten (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE CIS CD1 A B 38.931 NA NA TRGV4 TRDV1 IMMUNE SYSTEM 12/18/13 Structure of the DP10.7 TCR with CD1d-sulfatide homo sapiens mus musculus mus musculus mus musculus Luoma, A.M., Adams, E.J. 3.0058 X-RAY DIFFRACTION 0.207 0.178 True 7t2b O N NA NA abTCR 0 M peptide pneumolysin-derived peptide NA MH2 K L 37.610 TRBV6 TRAV17 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the 5F TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.250 0.216 True 4l4t H G NA NA abTCR 0 A Hapten 2-AMINO-4-OXO-3,4-DIHYDROPTERIDINE-6-CARBALDEHYDE 6FP MR1 A B 58.573 TRBV6 TRAV1 NA NA Membrane Protein/Immune System 07/17/13 Structure of human MAIT TCR in complex with human MR1-6-FP homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S.B.G., Birkinshaw, R.W., Beddoe, T., Corbett, A.J., Liu, L., Miles, J.J., Meehan, B., Reantragoon, R., Sandoval-Romero, M.L., Sullivan, L.C., Brooks, A.G., Chen, Z., Fairlie, D.P., McCluskey, J., Rossjohn, J. 2 X-RAY DIFFRACTION 0.225 0.184 True 6eh4 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV21 NA NA IMMUNE SYSTEM 04/18/18 003 Human T-Cell Receptor specific for HIV GAG epitope SLYNTVATL carried by Human Leukocyte Antigen HLA-A*0201 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.26 X-RAY DIFFRACTION 0.191 0.159 True 6vm7 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV19 TRAV8 NA NA IMMUNE SYSTEM 01/20/21 SILv44 T cell receptor bound to HLA-A2 presenting gp100 peptide (ITDQVPFSV) homo sapiens homo sapiens Smith, A.R., Baker, B.M. 2.41 X-RAY DIFFRACTION 0.241 0.199 True 8dnt P M NA NA abTCR 0 Q peptide nucleoprotein NA MH1 R T 34.990 NA NA NA NA IMMUNE SYSTEM 01/08/09 SARS-CoV-2 specific T cell receptor homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Gallagher, D.T., Wu, D., Gowthaman, R., Pierce, B.G., Mariuzza, R.A., Weng, N.P. 3.18 X-RAY DIFFRACTION 0.313 0.221 True 3tpu H G NA NA abTCR 0 L peptide p5e8 peptide NA MH1 K NA 42.016 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 p5E8/H2-Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 3.1 X-RAY DIFFRACTION 0.258 0.231 True 8gom E D NA NA abTCR 0 C peptide spike protein s2 NA MH1 A B 39.649 TRBV12 TRAV38 NA NA IMMUNE SYSTEM/VIRAL PROTEIN 03/01/23 SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-HLA-A2 homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 2.783 X-RAY DIFFRACTION 0.248 0.195 True 5d7l E D NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C F 42.506 TRBV28 TRAV36 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-5-OP-RU in complex with human MAV36 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 3.4 X-RAY DIFFRACTION 0.337 0.280 True 1d9k F E NA NA abTCR 0 Q peptide conalbumin peptide NA MH2 G H 51.674 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 12/15/99 CRYSTAL STRUCTURE OF COMPLEX BETWEEN D10 TCR AND PMHC I-AK/CA mus musculus mus musculus mus musculus mus musculus mus musculus Reinherz, E.L., Tan, K., Tang, L., Kern, P., Liu, J.-H., Xiong, Y., Hussey, R.E., Smolyar, A., Hare, B., Zhang, R., Joachimiak, A., Chang, H.-C., Wagner, G., Wang, J.-H. 3.2 X-RAY DIFFRACTION 0.293 0.247 True 3uts J I NA NA abTCR 0 H peptide insulin NA MH1 F G 35.225 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 01/25/12 1E6-A*0201-ALWGPDPAAA Complex, Monoclinic homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M. 2.712 X-RAY DIFFRACTION 0.269 0.201 True 6cqq E D NA NA abTCR 0 C peptide peptide from capsid protein p24 NA MH2 A B 34.233 TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of F24 TCR -DR15-RQ13 peptide complex homo sapiens homo sapiens hiv-1 m homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.254 0.207 True 3owe G NA NA NA NA 0 L protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 4l4v E D NA NA abTCR 0 C Hapten 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol 1VY MR1 C F 61.337 TRBV6 TRAV1 NA NA Membrane Protein/Immune System 07/17/13 Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S.B.G., Birkinshaw, R.W., Beddoe, T., Corbett, A.J., Liu, L., Miles, J.J., Meehan, B., Reantragoon, R., Sandoval-Romero, M.L., Sullivan, L.C., Brooks, A.G., Chen, Z., Fairlie, D.P., McCluskey, J., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.209 0.178 True 4wnq D NA NA NA NA 0 C protein tcr variable delta 1 chain and tcr constant alpha chain NA NA NA NA nan TRBV20 NA NA NA IMMUNE SYSTEM 11/26/14 THE MOLECULAR BASES OF DELTA/ALPHA-BETA T-CELL MEDIATED ANTIGEN RECOGNITION homo sapiens homo sapiens Pellicci, D.G., Uldrich, A.P., Le Nours, J., Ross, F., Chabrol, E., Eckle, S.B.G., de Boer, R., Lim, R.T., McPherson, K., Besra, G., Howell, A.R., Moretta, L., McCluskey, J., Heemskerk, M.H.M., Gras, S., Rossjohn, J., Godfrey, D.I. 1.8 X-RAY DIFFRACTION 0.229 0.193 True 4p46 B A NA NA abTCR 0 NA NA NA NA MH2 C D 41.017 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 05/28/14 J809.B5 Y31A TCR bound to IAb3K mus musculus mus musculus mus musculus synthetic construct, mus musculus Stadinski, B.D., Huseby, E.S., Trenh, P., Stern, L.J. 2.851 X-RAY DIFFRACTION 0.247 0.181 True 2aq3 E NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.3 X-RAY DIFFRACTION 0.271 0.206 True 5hhm J I NA NA abTCR 0 H peptide m1-f5l, gilglvftl NA MH1 F G 63.903 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 03/23/16 Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Gras, S., Josephs, T.M., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.289 0.216 True 1h5b NA D NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV4 NA NA T CELL RECEPTOR 06/21/01 T cell receptor Valpha11 (AV11S5) domain mus musculus Machius, M., Cianga, P., Deisenhofer, J., Sally Ward, E. 1.85 X-RAY DIFFRACTION 0.245 0.224 True 6mji D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-{[4-O-(cyclopropylmethyl)-alpha-D-galactopyranosyl]oxy}-3,4-dihydroxyoctadecan-2-yl]hexacosanamide JTD CD1 A B 26.178 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxs (JJ304) /iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2.3 X-RAY DIFFRACTION 0.227 0.189 True 3sjv O N NA NA abTCR 0 M peptide epstein-barr nuclear antigen 3 NA MH1 K L 35.963 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR in complex with HLA-B8-FLR homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.321 0.253 True 3e3q S R NA NA abTCR 0 T peptide ql9 peptide NA MH1 P NA 42.294 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 4n0c H G NA NA abTCR 0 F peptide pcpe3 NA MH1 E NA 46.685 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 08/19/15 42F3 TCR pCPE3/H-2Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 2.9 X-RAY DIFFRACTION 0.247 0.192 True 5c0b J I NA NA abTCR 0 H peptide marker peptide NA MH1 F G 43.895 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.03 X-RAY DIFFRACTION 0.231 0.192 True 8en8 J I NA NA abTCR 0 H peptide nucleoprotein np4 epitope NA MH1 F G 41.851 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP4 epitope from 1972 influenza strain homo sapiens homo sapiens influenza a virus (strain a/memphis/101/1972h3n2) homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.70001 X-RAY DIFFRACTION 0.249 0.207 True 8es8 B A NA NA abTCR 0 P peptide melanoma-associated antigen 4 NA MH1 N M 46.058 TRBV28 TRAV14 NA NA IMMUNE SYSTEM 05/03/23 CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239) homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Saotome, K., Franklin, M.C. 2.65 ELECTRON MICROSCOPY NA NA True 2apw A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the G17E/A52V/S54N/K66E/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2 X-RAY DIFFRACTION 0.239 0.197 True 7pb2 E D NA NA abTCR 0 C peptide kras g12d peptide (vvvgadgvgk) NA MH1 A B 44.476 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 07/20/22 Crystal structure of JDI TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK) homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Karuppiah, V., Robinson, R.A. 3.41 X-RAY DIFFRACTION 0.254 0.228 True 6xng D C NA NA abTCR 0 A Hapten (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide V8P CD1 A B 26.877 TRBV13 TRAV11 NA NA LIPID BINDING PROTEIN 11/10/21 MHC-like protein complex structure mus musculus mus musculus mus musculus mus musculus mus musculus Thirunavukkarasu, P., Le Nours, J., Rossjohn, J. 2.79 X-RAY DIFFRACTION 0.277 0.203 True 8sgb D C NA NA abTCR 0 A | E Hapten | carbohydrate sphingomyelin | N-ACETYL-D-GLUCOSAMINE FO4 | NAG CD1 A B 59.964 TRBV19 TRAV26 NA NA IMMUNE SYSTEM 04/24/24 Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Chan Yew Poa, K.T.O., Le Nours, J., Rossjohn, J. 2.80002 X-RAY DIFFRACTION 0.249 0.208 True 3q5y B NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV12 NA NA NA IMMUNE SYSTEM 03/09/11 V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures mus musculus Chen, Q., Zhang, H., Wang, J.-H. 1.9 X-RAY DIFFRACTION 0.218 0.178 True 7q9b E D NA NA abTCR 0 C peptide unknown NA MH1 A B 47.309 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR Rizkallah, P.J., Sewell, A.K., Wall, A., Fuller, A. 3.24 X-RAY DIFFRACTION 0.277 0.226 False 8wul D C NA NA abTCR 0 N peptide kras-g12v nonamer peptide NA MH1 L M 64.958 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 05/01/24 Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Zhang, M.Y., Luo, L.J., Xu, W., Guan, F.H., Wang, X.Y., Zhu, P., Zhang, J.H., Zhou, X.Y., Wang, F., Ye, S. 2.36 X-RAY DIFFRACTION 0.235 0.190 True 1mwa D C NA NA abTCR 0 Q peptide dev8 NA MH1 I M 26.226 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/27/02 2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX mus musculus mus musculus mus musculus mus musculus Luz, J.G., Huang, M.D., Garcia, K.C., Rudolph, M.G., Teyton, L., Wilson, I.A. 2.4 X-RAY DIFFRACTION 0.313 0.284 True 4qrp I J NA NA abTCR 0 H peptide ns3-4a protein NA MH1 F G 50.258 TRBV11 TRAV9 NA NA IMMUNE SYSTEM 11/12/14 Crystal Structure of HLA B*0801 in complex with HSKKKCDEL and DD31 TCR homo sapiens homo sapiens hepatitis c virus homo sapiens homo sapiens Gras, S., Berry, R., Lucet, I.S., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.248 0.207 True 6rpa E D NA NA abTCR 0 C peptide heteroclitic ny-eso-1 157-165 peptide NA MH1 A B 73.251 TRBV29 TRAV3 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S2 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 2.56 X-RAY DIFFRACTION 0.293 0.250 True 6xqp H G NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 51.793 TRBV29 TRAV12 NA NA IMMUNE SYSTEM 08/26/20 Structure of human D462-E4 TCR in complex with human MR1-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.235 0.190 True 4pjb H G NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 58.540 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.85 X-RAY DIFFRACTION 0.225 0.165 True 4irs D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-1-{[6-O-(pyridin-4-ylcarbamoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide 1LA CD1 A B 25.613 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 09/04/13 Structure of the mouse CD1d-PyrC-alpha-GalCer-iNKT TCR complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Nemcovic, M., Zajonc, D.M. 2.8 X-RAY DIFFRACTION 0.239 0.190 True 2e7l D A NA NA abTCR 0 Q peptide peptide (gln)(leu)(ser)(pro)(phe)(pro)(phe)(asp)(leu) NA MH1 E NA 44.905 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 04/24/07 Structure of a high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Garcia, K.C., Colf, L.A. 2.5 X-RAY DIFFRACTION 0.246 0.224 True 7n5p E D NA NA abTCR 0 C peptide peptide from polymerase acidic protein NA MH1 A B 39.635 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 07/20/22 6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant mus musculus, homo sapiens mus musculus, homo sapiens influenza a virus mus musculus homo sapiens Szeto, C., Gras, S. 2.09 X-RAY DIFFRACTION 0.236 0.190 True 3to4 D C NA NA abTCR 0 A carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 A B 27.549 TRBV1 TRAV11 NA NA IMMUNE SYSTEM 12/14/11 Structure of mouse Valpha14Vbeta2-mouseCD1d-alpha-Galactosylceramide homo sapiens, mus musculus homo sapiens, mus musculus mus musculus mus musculus mus musculus Patel, O., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.268 0.217 True 4pjc H G NA NA abTCR 0 C | C Hapten | Hapten 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL B3P | 2LJ MR1 C D 61.478 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT C-A11 TCR homo sapiens homo sapiens homo sapiens | homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.214 0.167 True 3o6f H G NA NA abTCR 0 NA NA NA NA MH2 E F 36.991 TRBV20 TRAV26 NA NA IMMUNE SYSTEM 03/02/11 Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4 homo sapiens homo sapiens homo sapiens homo sapiens Yin, Y., Li, Y., Martin, R., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.279 0.239 True 1jck C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA COMPLEX (TOXIN/RECEPTOR) 11/12/97 T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SEC3 SUPERANTIGEN mus musculus Fields, B.A., Mariuzza, R.A. 3.5 X-RAY DIFFRACTION 0.328 0.238 True 7n1f E D NA NA abTCR 0 C peptide spike protein s1 NA MH1 A B 41.824 TRBV7 TRAV12 NA NA IMMUNE SYSTEM 07/28/21 SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 binds to YLQ-HLA-A2 homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 2.393 X-RAY DIFFRACTION 0.236 0.197 True 5c0c E D NA NA abTCR 0 H peptide marker peptide NA MH1 F G 43.754 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying RQFGPDWIVA homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 1.974 X-RAY DIFFRACTION 0.227 0.189 True 6dfw H G NA NA abTCR 0 NA NA NA NA MH2 C D 48.713 TRBV13 TRAV5 NA NA IMMUNE SYSTEM 04/17/19 TCR 8F10 in complex with IAg7-p8G9E mus musculus mus musculus mus musculus mus musculus Wang, Y., Dai, S. 3.2 X-RAY DIFFRACTION 0.297 0.233 True 5ksb F E NA NA abTCR 0 I peptide dq8.5-glia-gamma1 peptide NA MH2 C D 33.368 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 09/21/16 T15-DQ8.5-glia-gamma1 complex homo sapiens homo sapiens triticum aestivum homo sapiens triticum aestivum, homo sapiens Petersen, J., Rossjohn, J., Reid, H.H. 2.9 X-RAY DIFFRACTION 0.254 0.219 True 6mjq H G NA NA abTCR 0 E Hapten N-{(2S,3S,4R)-3,4-dihydroxy-1-[(4-O-{[4-(trifluoromethyl)phenyl]methyl}-alpha-D-galactopyranosyl)oxy]octadecan-2-yl}hexacosanamide JUD CD1 E F 26.034 TRBV13 TRAV11 NA NA immune system/inhibitor 01/09/19 Crystal structure of the mCD1d/xxp (JJ295) /iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 3 X-RAY DIFFRACTION 0.258 0.215 True 6d78 E D NA NA abTCR 0 C peptide melanoma antigen recognized by t-cells 1 NA MH1 A B 32.745 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 04/03/19 The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Hellman, L.M., Singh, N.K. 2.347 X-RAY DIFFRACTION 0.255 0.204 True 4jff E D NA NA abTCR 0 C peptide melanoma motif NA MH1 A B 42.977 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 05/29/13 Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K. 2.43 X-RAY DIFFRACTION 0.263 0.210 True 8i5c i h NA NA abTCR 0 g peptide unknown NA MH1 e f 47.631 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 False 3e3q E D NA NA abTCR 0 Q peptide ql9 peptide NA MH1 A NA 44.850 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 1zgl R Q NA NA abTCR 0 F peptide myelin basic protein NA MH2 D E 39.901 TRBV5 TRAV9 NA NA IMMUNE SYSTEM 10/18/05 Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Li, Y., Huang, Y., Lue, J., Quandt, J.A., Martin, R., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.329 0.280 True 6pui E D NA NA abTCR 0 C Hapten 6-[(4-hydroxybutyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione Q7P MR1 C F 58.923 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-4'OH-Butyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.96 X-RAY DIFFRACTION 0.200 0.157 True 2bnu B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV21 NA NA IMMUNE SYSTEM/RECEPTOR 05/24/05 Structural and kinetic basis for heightened immunogenicity of T cell vaccines homo sapiens homo sapiens Chen, J.-L., Stewart-Jones, G., Bossi, G., Lissin, N.M., Wooldridge, L., Choi, E.M.L., Held, G., Dunbar, P.R., Esnouf, R.M., Sami, M., Boultier, J.M., Rizkallah, P.J., Renner, C., Sewell, A., Van Der Merwe, P.A., Jackobsen, B.K., Griffiths, G., Jones, E.Y., Cerundolo, V. 1.4 X-RAY DIFFRACTION unknown 0.245 True 5swz E D NA NA abTCR 0 C peptide influenza np366 epitope NA MH1 A B 52.083 TRBV17 TRAV14 NA NA IMMUNE SYSTEM 10/05/16 Crystal Structure of NP1-B17 TCR-H2Db-NP complex mus musculus mus musculus unidentified influenza virus mus musculus mus musculus Gras, S., Del Campo, C.M., Farenc, C., Josephs, T.M., Rossjohn, J. 2.65 X-RAY DIFFRACTION 0.249 0.226 True 4n5e D C NA NA abTCR 0 B peptide pcpa12 NA MH1 A NA 45.286 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 08/19/15 42F3 TCR pCPA12/H-2Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 3.059 X-RAY DIFFRACTION 0.227 0.194 True 8ye4 J I NA NA abTCR 0 F peptide spike protein s1 NA MH1 C D 56.191 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 08/21/24 The complex of TCR NYN-I and HLA-A24 bound to SARS-CoV-2 Spike448-456 peptide NYNYLYRLF homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Deng, S.S., Jin, T.C., Xu, Z.H., Wang, M.H. 3.2 X-RAY DIFFRACTION 0.310 0.266 True 7ryl NA NA D C gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV4 TRDV1 IMMUNE SYSTEM 05/18/22 T cell receptor CO3 homo sapiens homo sapiens Wegrecki, M., Le Nours, J., Rossjohn, J. 2 X-RAY DIFFRACTION 0.247 0.199 True 5wjo B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV26 NA NA IMMUNE SYSTEM 10/25/17 Crystal structure of the unliganded PG90 TCR homo sapiens homo sapiens Shahine, A., Gras, S., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.230 0.208 True 3of6 C NA NA NA NA 0 E protein pre t-cell antigen receptor alpha NA NA NA NA nan TRBV7 NA NA NA IMMUNE SYSTEM 10/20/10 Human pre-T cell receptor crystal structure homo sapiens homo sapiens Pang, S.S. 2.8 X-RAY DIFFRACTION 0.240 0.175 True 4p5t B A NA NA abTCR 0 NA NA NA NA MH2 C D 44.567 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 05/28/14 14.C6 TCR complexed with MHC class II I-Ab/3K peptide homo sapiens homo sapiens mus musculus mus musculus Trenh, P., Stadinski, B., Huseby, E.S., Stern, L.J. 3.263 X-RAY DIFFRACTION 0.236 0.186 True 4pjb F E NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 56.926 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.85 X-RAY DIFFRACTION 0.225 0.165 True 2xn9 B A NA NA abTCR 0 C protein enterotoxin h NA NA NA NA nan TRBV19 TRAV27 NA NA IMMUNE SYSTEM 11/24/10 Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin H and human major histocompatibility complex class II homo sapiens homo sapiens staphylococcus aureus Saline, M., Rodstrom, K.E.J., Fischer, G., Orekhov, V.Y., Karlsson, B.G., Lindkvist-Petersson, K. 2.3 X-RAY DIFFRACTION 0.27236 0.22150 True 4jrx E D NA NA abTCR 0 C peptide trans-activator protein bzlf1 NA MH1 A B 67.964 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 04/10/13 Crystal Structure of CA5 TCR-HLA B*3505-LPEP complex homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Liu, Y.C., Rossjohn, J., Gras, S. 2.3 X-RAY DIFFRACTION 0.257 0.205 True 7nmf E D NA NA abTCR 0 C peptide gln-leu-pro-arg-leu-phe-pro-leu-leu NA MH1 A B 36.294 TRBV7 TRAV5 NA NA IMMUNE SYSTEM 09/07/22 Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Sewell, A.K., Cole, D.K., Wall, A. 2.98 X-RAY DIFFRACTION 0.259 0.182 True 3sdc D C NA NA abTCR 0 A Hapten N-[(2S,3R,4E)-1-{[ALPHA-D-GALACTOPYRANOSYL-(1->4)-BETA-D-GALACTOPYRANOSYL-(1->4)-BETA-D-GLUCOPYRANOSYL]OXY}-3-HYDROXYOCTADEC-4-EN-2-YL]HEXACOSANAMIDE 3GB CD1 A B 24.219 TRBV19 TRAV11 NA NA IMMUNE SYSTEM 10/05/11 Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-globotrihexosylceramide mus musculus , homo sapiens mus musculus , homo sapiens mus musculus mus musculus mus musculus Clarke, A.J., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.292 0.240 True 6dfv B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV5 NA NA IMMUNE SYSTEM 04/17/19 Mouse diabetogenic TCR 8F10 mus musculus mus musculus Wang, Y., Dai, S. 1.71 X-RAY DIFFRACTION 0.231 0.171 True 6jxr n m NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 09/11/19 Structure of human T cell receptor-CD3 complex homo sapiens homo sapiens Dong, D., Zheng, L., Lin, J., Zhu, Y., Li, N., Zhang, B., Xie, S., Zheng, J., Wang, Y., Gao, N., Huang, Z. 3.7 ELECTRON MICROSCOPY NA NA False 3qiw D C NA NA abTCR 0 E peptide mcc-p5e peptide NA MH2 A B 39.865 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek mus musculus manduca sexta mus musculus mus musculus mus musculus Kruse, A.C., Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 3.3 X-RAY DIFFRACTION 0.267 0.212 True 4y4k D C NA NA abTCR 0 A Hapten (4Z)-9-[(1R,2R)-2-decylcyclopropyl]-N-[(2S,3S,4S)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]non-4-enamide 49Y CD1 A B 25.342 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/EF77/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Birkholz, A.M. 2.9 X-RAY DIFFRACTION 0.267 0.207 True 6cqr J I NA NA abTCR 0 H peptide peptide from capsid protein p24 NA MH2 F G 31.334 TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of F24 TCR -DR1-RQ13 peptide complex homo sapiens homo sapiens hiv-1 m homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 3.04 X-RAY DIFFRACTION 0.254 0.223 True 7ryo NA NA D C gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV4 TRDV1 IMMUNE SYSTEM 05/18/22 CD1a-dideoxymycobactin-gdTCR complex homo sapiens homo sapiens Wegrecki, M., Le Nours, J., Rossjohn, J. 3 X-RAY DIFFRACTION 0.267 0.222 True 6cug E D NA NA abTCR 0 A | D Hapten | Hapten TETRACOSYL OCTADECANOATE | (2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL 2-(TRIMETHYLAMMONIO)ETHYL PHOSPHATE CUY | POV CD1 A NA 86.824 TRBV6 TRAV9 NA NA IMMUNE SYSTEM 01/16/19 Crystal structure of BC8B TCR-CD1b-PC complex homo sapiens homo sapiens homo sapiens | homo sapiens homo sapiens Shahine, A.E., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.229 0.187 True 2aq1 E NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.1 X-RAY DIFFRACTION 0.243 0.185 True 6zkx E D NA NA abTCR 0 C peptide enoyl-[acyl-carrier-protein] reductase [nadh] NA MH1 A B 60.624 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 01/26/22 Crystal structure of InhA:01 TCR in complex with HLA-E (Y84C) bound to InhA (53-61 GCG) homo sapiens homo sapiens mycobacterium tuberculosis h37rv homo sapiens homo sapiens Srikannathasan, V., Karuppiah, V., Robinson, R.A. 2.17 X-RAY DIFFRACTION 0.244 0.209 True 6fr6 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.98 X-RAY DIFFRACTION 0.299 0.201 True 3mc0 C NA NA NA NA 0 B protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 10/13/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, E.L. 2 X-RAY DIFFRACTION 0.211 0.179 True 7rym NA NA D C gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV4 TRDV1 IMMUNE SYSTEM 05/18/22 CD1a-endo-gdTCR complex homo sapiens homo sapiens Wegrecki, M., Le Nours, J., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.286 0.247 True 7s8i B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV27 TRAV27 NA NA IMMUNE SYSTEM 11/02/22 PHOSPHOPEPTIDE-SPECIFIC LC13 TCR, MONOCLINIC CRYSTAL FORM homo sapiens homo sapiens Patskovsky, Y., Nyovanie, S., Patskovska, L., Natarajan, A., Joshi, B., Morin, B., Brittsan, C., Huber, O., Gordon, S., Michelet, X., Schmitzberger, F., Stein, R., Findeis, M., Hurwitz, A., Van Dijk, M., Buell, J., Underwood, D., Krogsgaard, M. 1.66 X-RAY DIFFRACTION 0.216 0.167 True 4nqc E D NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C F 59.762 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TCR-MR1 ternary complex and covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.216 0.165 True 2ak4 P N NA NA abTCR 0 M peptide ebv peptide lpeplpqgqltay NA MH1 K L 66.835 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 10/11/05 Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N.A., Miles, J.J., Beddoe, T., Whisstock, J.C., Wilce, M.C., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Konstenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.278 0.246 True 1nam B A NA NA abTCR 0 P peptide nucleocapsid NA MH1 H L 39.971 TRBV1 TRAV16 NA NA IMMUNE SYSTEM 03/11/03 MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX mus musculus mus musculus mus musculus mus musculus Reiser, J.-B., Darnault, C., Gregoire, C., Mosser, T., Mazza, G., Kearnay, A., van der Merwe, P.A., Fontecilla-Camps, J.C., Housset, D., Malissen, B. 2.7 X-RAY DIFFRACTION 0.298 0.230 True 8pjg E D NA NA abTCR 0 C peptide hemagglutinin ha2 chain NA MH2 A B 48.209 TRBV24 TRAV8 NA NA IMMUNE SYSTEM 06/19/24 F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens MacLachlan, B.J., Wall, A., Greenshields-Watson, A.L., Cole, D.K., Rizkallah, P.J., Godkin, A.J. 1.83 X-RAY DIFFRACTION 0.214 0.181 True 3qjf D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 Crystal structure of the 2B4 TCR mus musculus mus musculus Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 2.4 X-RAY DIFFRACTION 0.259 0.210 True 4jfh E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV30 TRAV12 NA NA IMMUNE SYSTEM 05/29/13 High Affinity alpha24-beta17 T Cell Receptor for A2 HLA-Melanoma peptide complex homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K. 2.4 X-RAY DIFFRACTION 0.247 0.201 True 5d2l J I NA NA abTCR 0 Q peptide asn-leu-val-pro-met-val-ala-thr-val NA MH1 A B 29.444 TRBV7 TRAV24 NA NA IMMUNE SYSTEM 10/07/15 Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2 homo sapiens homo sapiens cytomegalovirus homo sapiens homo sapiens Gao, M., Mariuzza, R.A. 3.511 X-RAY DIFFRACTION 0.355 0.270 True 4onh B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV36 NA NA IMMUNE SYSTEM 10/08/14 Crystal Structure of DN6 TCR homo sapiens homo sapiens Roy, S., Adams, E.J. 3.008 X-RAY DIFFRACTION 0.317 0.257 True 8vcx E D NA NA abTCR 0 C peptide proinsulin c-peptide (insc8-22) NA MH2 A B 32.406 TRBV5 TRAV26 NA NA IMMUNE SYSTEM 08/07/24 Human TCR A2.13 in complex with DQ8-InsCpep homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Lim, J.J., Loh, T.J., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.59 X-RAY DIFFRACTION 0.238 0.203 True 7n1d B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV12 NA NA IMMUNE SYSTEM 07/28/21 SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 2.35 X-RAY DIFFRACTION 0.272 0.204 True 6pvc H G NA NA abTCR 0 A Hapten N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alanine P1J MR1 A B 59.293 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/01/20 Structure of human MAIT A-F7 TCR in complex with human MR1-DB28 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.96 X-RAY DIFFRACTION 0.212 0.169 True 3c60 B A NA NA abTCR 0 NA NA NA NA MH2 C D 49.686 TRBV13 TRAV6 NA NA SUGAR BINDING PROTEIN/IMMUNE SYSTEM 04/29/08 Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR YAe62 mus musculus mus musculus mus musculus mus musculus Dai, S. 3.05 X-RAY DIFFRACTION 0.309 0.267 True 4nhu B A NA NA abTCR 0 NA NA NA NA MH1 G NA 85.855 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 05/06/15 The M33 TCR p3M33l/H-2 Ld Complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 2.9 X-RAY DIFFRACTION 0.260 0.229 True 5yxu B A NA NA abTCR 0 I peptide lys-leu-val-ala-leu-gly-ile-asn-ala-val NA MH1 C D 31.712 TRBV25 TRAV38 NA NA IMMUNE SYSTEM 12/12/18 an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV homo sapiens homo sapiens hepatitis c virus homo sapiens homo sapiens Yi, L. 2.7 X-RAY DIFFRACTION 0.289 0.235 True 4z7v H G NA NA abTCR 0 J peptide deamidated dq8-glia-alpha1 peptide NA MH2 A B 38.981 TRBV9 TRAV26 NA NA IMMUNE SYSTEM 06/03/15 L3-12 complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Rossjohn, J., Reid, H.H., Koning, F. 2.65 X-RAY DIFFRACTION 0.226 0.187 True 6fra B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.73 X-RAY DIFFRACTION 0.243 0.203 True 3r8b P NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 2axj B NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV19 NA NA NA IMMUNE SYSTEM 09/20/05 Crystal structures of T cell receptor beta chains related to rheumatoid arthritis homo sapiens Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y. 2.65 X-RAY DIFFRACTION 0.286 0.233 True 8vz9 D C NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 57.628 TRBV13 TRAV1 NA NA IMMUNE SYSTEM 04/10/24 Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex mus musculus mus musculus mus musculus mus musculus mus musculus Ciacchi, L., Rossjohn, J., Awad, W. 3.4 X-RAY DIFFRACTION 0.263 0.242 True 2nx5 P N NA NA abTCR 0 H peptide ebv peptide, eplpqgqltay NA MH1 K L 61.579 TRBV10 TRAV1 NA NA IMMUNE SYSTEM 02/27/07 Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Reid, H.H., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.327 0.269 True 6mnm B A NA NA abTCR 0 NA NA NA NA MH2 C D 42.797 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/03/19 6256 TCR bound to I-Ab Padi4 mus musculus mus musculus mus musculus mus musculus Blevins, S.J., Stadinski, B.D., Huseby, E.S. 3.1 X-RAY DIFFRACTION 0.265 0.220 True 4p2r J I NA NA abTCR 0 H peptide 5c1 peptide NA MH2 F G 31.752 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.295 X-RAY DIFFRACTION 0.243 0.212 True 3o4l E D NA NA abTCR 0 C peptide bslf2/bmlf1 protein NA MH1 A B 46.314 TRBV20 TRAV5 NA NA IMMUNE SYSTEM 01/12/11 Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Miles, J.J., Bulek, A.M., Cole, D.K., Gostick, E., Schauenburg, J.A., Dolton, G., Venturi, V., Davenport, M.P., Tan, M.P., Burrows, S.R., Wooldridge, L., Price, D.A., Rizkallah, P.J., Sewell, A.K. 2.54 X-RAY DIFFRACTION 0.296 0.221 False 1i9e NA A NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV9 NA NA IMMUNE SYSTEM 12/05/01 TCR DOMAIN mus musculus Rudolph, M.G., Huang, M., Teyton, L., Wilson, I.A. 2.5 X-RAY DIFFRACTION 0.233 0.203 True 4y4f D C NA NA abTCR 0 A Hapten (1R)-1,5-anhydro-1-[(1E,3S,4S,5R)-4,5-dihydroxy-3-(nonacosanoylamino)nonadec-1-en-1-yl]-D-galactitol 49M CD1 A B 26.318 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/GCK127/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Yu, E.D. 3.19 X-RAY DIFFRACTION 0.257 0.218 True 2nw2 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV10 TRAV1 NA NA IMMUNE SYSTEM 02/27/07 Crystal structure of ELS4 TCR at 1.4A homo sapiens homo sapiens Tynan, F.E., Reid, H.H., Rossjohn, J. 1.4 X-RAY DIFFRACTION 0.224 0.192 True 6pug H G NA NA abTCR 0 A Hapten 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione OZD MR1 A B 60.435 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-2`OH-Ethyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.8 X-RAY DIFFRACTION 0.194 0.160 True 2pyf B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV21 NA NA IMMUNE SYSTEM 09/25/07 Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry Unbound TCR Clone 5-1 homo sapiens homo sapiens Sami, M., Rizkallah, P.J., Dunn, S., Li, Y., Moysey, R., Vuidepot, A., Baston, E., Todorov, P., Molloy, P., Gao, F., Boulter, J.M., Jakobsen, B.K. 2.2 X-RAY DIFFRACTION 0.295 0.209 True 3sdd D C NA NA abTCR 0 A Hapten N-[(2S,3R,4E)-1-{[4-O-(BETA-D-GALACTOPYRANOSYL)-BETA-D-GLUCOPYRANOSYL]OXY}-3-HYDROXYOCTADEC-4-EN-2-YL]DOCOSANAMIDE 3GD CD1 A B 24.785 TRBV19 TRAV11 NA NA IMMUNE SYSTEM 10/05/11 Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-beta-lactosylceramide mus musculus , homo sapiens mus musculus , homo sapiens mus musculus mus musculus mus musculus Clarke, A.J., Rossjohn, J. 3 X-RAY DIFFRACTION 0.318 0.258 True 3arf D C NA NA abTCR 0 A Hapten (11Z,14E)-N-[(2S,3S,4R)-1-(ALPHA-D-GALACTOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]ICOSA-11,14-DIENAMIDE DB3 CD1 A B 23.833 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 03/30/11 Ternary crystal structure of the mouse NKT TCR-CD1d-C20:2 mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wun, K.S., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.277 0.225 True 6dfs B A NA NA abTCR 0 NA NA NA NA MH2 C D 36.364 TRBV1 TRAV10 NA NA IMMUNE SYSTEM 04/17/19 mouse TCR I.29 in complex with IAg7-p8E9E6ss mus musculus mus musculus mus musculus mus musculus Wang, Y., Dai, S. 3.1 X-RAY DIFFRACTION 0.285 0.240 True 6w9v H G NA NA abTCR 0 NA NA NA NA MR1 A B 60.110 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 08/05/20 Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H without ligand homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.95 X-RAY DIFFRACTION 0.200 0.160 True 7sg2 J I NA NA abTCR 0 H peptide dq2-glia-omega1 peptide NA MH2 F G 34.514 TRBV29 TRAV4 NA NA IMMUNE SYSTEM 02/23/22 XPA5 TCR in complex with HLA-DQ2-omega1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.259 0.218 True 4p2r T S NA NA abTCR 0 R peptide 5c1 peptide NA MH2 P Q 31.485 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.295 X-RAY DIFFRACTION 0.243 0.212 True 3he7 D C NA NA abTCR 0 A carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 A B 29.416 TRBV29 TRAV11 NA NA IMMUNE SYSTEM 07/28/09 Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta7 NKT TCR mus musculus mus musculus mus musculus mus musculus mus musculus Patel, O., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.271 0.224 True 6puc E D NA NA abTCR 0 C Hapten 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol Q87 MR1 C F 59.048 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.85 X-RAY DIFFRACTION 0.178 0.159 True 4pjx H G NA NA abTCR 0 C | C Hapten | Hapten 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE B3P | 30W MR1 C D 58.738 TRBV6 TRAV1 NA NA Immune System 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT C-A11 TCR homo sapiens homo sapiens homo sapiens | homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.25 X-RAY DIFFRACTION 0.203 0.170 True 6dfw F E NA NA abTCR 0 NA NA NA NA MH2 A B 48.670 TRBV13 TRAV5 NA NA IMMUNE SYSTEM 04/17/19 TCR 8F10 in complex with IAg7-p8G9E mus musculus mus musculus mus musculus mus musculus Wang, Y., Dai, S. 3.2 X-RAY DIFFRACTION 0.297 0.233 True 4p23 B A NA NA abTCR 0 NA NA NA NA MH2 C D 40.420 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 05/28/14 J809.B5 TCR bound to IAb/3K mus musculus mus musculus mus musculus mus musculus Stadinski, B.D., Huseby, E.S., Trenh, P., Stern, L. 2.25 X-RAY DIFFRACTION 0.212 0.164 True 8enh T S NA NA abTCR 0 R peptide nucleoprotein np7 epitope NA MH1 P Q 42.054 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain homo sapiens homo sapiens influenza a virus (strain a/2002/h3n2) homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.50003 X-RAY DIFFRACTION 0.230 0.191 True 1kgc E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV26 NA NA IMMUNE SYSTEM 12/11/02 Immune Receptor homo sapiens homo sapiens Kjer-Nielsen, L., Clements, C.S., Brooks, A.G., Purcell, A.W., McCluskey, J., Rossjohn, J. 1.5 X-RAY DIFFRACTION 0.234 0.211 True 6bnk D C NA NA abTCR 0 A carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 A B 26.934 NA NA NA NA IMMUNE SYSTEM 04/04/18 Crystal structure of TCR-MHC-like molecule homo sapiens homo sapiens mus musculus mus musculus mus musculus Le Nours, J., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.220 0.201 True 8gon E D NA NA abTCR 0 C peptide spike protein s2 NA MH1 A B 38.984 TRBV12 TRAV38 NA NA IMMUNE SYSTEM/VIRAL PROTEIN 03/01/23 SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-T1006I-HLA-A2 homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 2.601 X-RAY DIFFRACTION 0.253 0.198 True 7t2d E D NA NA abTCR 0 C peptide pneumolysin-derived peptide NA MH2 A B 54.137 TRBV7 TRAV19 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the B1 TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.4 X-RAY DIFFRACTION 0.271 0.236 True 7n1c E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV11 TRAV16 NA NA IMMUNE SYSTEM 07/28/21 SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 1.881 X-RAY DIFFRACTION 0.239 0.201 True 3qeu B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/06/11 The crystal structure of TCR DMF5 homo sapiens homo sapiens Borbulevych, O.Y., Santhanagopolan, S.M., Baker, B.M. 2.09 X-RAY DIFFRACTION 0.266 0.206 True 4nqe E D NA NA abTCR 0 C Hapten 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxoethylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol 2L4 MR1 C F 61.792 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TCR-MR1 ternary complex bound to 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.222 0.182 True 4elk D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Crystal structure of the Hy19.3 type II NKT TCR mus musculus mus musculus Girardi, E., Maricic, I., Wang, J., Mac, T.T., Iyer, P., Kumar, V., Zajonc, D.M. 2.1 X-RAY DIFFRACTION 0.227 0.188 True 2aq1 A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.1 X-RAY DIFFRACTION 0.243 0.185 True 6vth B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 06/17/20 p53-specific T cell receptor homo sapiens homo sapiens Wu, D., Gallagher, D.T., Gowthaman, R., Pierce, B.G., Mariuzza, R.A. 2.36 X-RAY DIFFRACTION 0.264 0.212 True 2jcc F E NA NA abTCR 0 C peptide p1049 NA MH1 A B 67.753 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 10/09/07 AH3 recognition of mutant HLA-A2 W167A mus musculus mus musculus homo sapiens homo sapiens homo sapiens Miller, P., Benhar, Y.P., Biddison, W., Collins, E.J. 2.5 X-RAY DIFFRACTION 0.292 0.242 True 6miy D C NA NA abTCR 0 A Hapten N-{(2S,3S,4R)-1-[(4-O-benzyl-alpha-D-galactopyranosyl)oxy]-3,4-dihydroxyoctadecan-2-yl}hexacosanamide JTV CD1 A B 25.893 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxa (JJ239)/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2.75 X-RAY DIFFRACTION 0.247 0.192 True 3o9w D C NA NA abTCR 0 A Hapten (2S)-3-(ALPHA-D-GALACTOPYRANOSYLOXY)-2-(HEXADECANOYLOXY)PROPYL (9Z)-OCTADEC-9-ENOATE 1O2 CD1 A B 27.007 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 09/29/10 Recognition of a Glycolipid Antigen by the iNKT Cell TCR mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Li, Y. 2.8 X-RAY DIFFRACTION 0.258 0.195 True 6g9q H G NA NA abTCR 0 P peptide dopamine beta-hydroxylase NA MH1 A B 42.091 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 04/24/19 Ternary complex of P14 TCR with murine MHC class I H-2 Db in complex with self-antigen derived from dopamine monooxygenase. mus musculus mus musculus mus musculus mus musculus mus musculus Achour, A., Sandalova, T., Allerbring, E. 1.89 X-RAY DIFFRACTION 0.248 0.187 True 4pjh H G NA NA abTCR 0 C Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 C D 59.566 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-G8 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.198 0.169 True 7zt7 E D NA NA abTCR 0 NA NA NA NA MR1 A B 60.945 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex in human MR1 bound to 5FSA homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Robinson, R.A. 1.84 X-RAY DIFFRACTION 0.255 0.207 True 5c0b E D NA NA abTCR 0 C peptide marker peptide NA MH1 A B 45.151 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.03 X-RAY DIFFRACTION 0.231 0.192 True 2wbj H G NA NA abTCR 0 NA NA NA NA MH2 E F 79.467 TRBV20 TRAV17 NA NA IMMUNE SYSTEM 04/07/09 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens Harkiolaki, M., Holmes, S.L., Svendsen, P., Gregersen, J.W., Jensen, L.T., McMahon, R., Friese, M.A., van Boxel, G., Etzensperger, R., Tzartos, J.S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E.D., Palace, J., Esiri, M.M., van der Merwe, P.A., Jones, E.Y., Fugger, L. 3 X-RAY DIFFRACTION 0.288 0.247 True 6vmx J I NA NA abTCR 0 H peptide epstein-barr nuclear antigen 3 NA MH1 F G 54.949 TRBV4 TRAV24 NA NA IMMUNE SYSTEM 07/29/20 Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope homo sapiens homo sapiens epstein-barr virus (strain b95-8) homo sapiens homo sapiens Farenc, C., Rossjohn, J., Gras, S. 3.1 X-RAY DIFFRACTION 0.242 0.221 True 3utp L K NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV12 NA NA IMMUNE SYSTEM 01/25/12 1E6 TCR specific for HLA-A*0201-ALWGPDPAAA homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M. 2.574 X-RAY DIFFRACTION 0.291 0.230 True 3tf7 G g NA NA abTCR 0 F peptide ql9 peptide (qlspfpfdl) NA MH1 E NA 51.219 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3 QL9/H2-Ld complex mus musculus mus musculus mus musculus Adams, J.J., Kranz, D.M., Garcia, K.C. 2.75 X-RAY DIFFRACTION 0.261 0.237 True 1b88 NA B NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV14 NA NA IMMUNE SYSTEM 02/16/99 V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN mus musculus Plaksin, D., Chacko, S., Navaza, J., Margulies, D.H., Padlan, E.A. 2.5 X-RAY DIFFRACTION 0.324 0.224 True 6bj8 H NA NA NA NA 0 D | C protein | peptide tcr 55 alpha chain | val-pro-leu-thr-glu-asp-ala-glu-leu NA | NA MH1 A B nan TRBV6 NA NA NA IMMUNE SYSTEM 07/25/18 TCR55 in complex with Pep20/HLA-B35 homo sapiens homo sapiens | synthetic construct homo sapiens homo sapiens Jude, K.M., Sibener, L.V., Yang, X., Garcia, K.C. 1.75 X-RAY DIFFRACTION 0.183 0.159 True 6dkp E D NA NA abTCR 0 C peptide melanoma antigen recognized by t-cells 1 NA MH1 A B 31.997 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 04/10/19 The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Hellman, L.M., Singh, N.K. 2.966 X-RAY DIFFRACTION 0.286 0.229 True 3quy D C NA NA abTCR 0 A Hapten (2S,3R,4S,5R,6S)-6-[(2S,3S,4R)-2-(HEXACOSANOYLAMINO)-3,4-DIHYDROXY-OCTADECOXY]-3,4,5-TRIHYDROXY-N-(PHENYLMETHYL)OXANE-2-CARBOXAMIDE QUY CD1 A B 25.367 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 06/29/11 Structure of the mouse CD1d-BnNH-GSL-1'-iNKT TCR complex mus musculus mus musculus mus musculus mus musculus mus musculus Li, Y., Girardi, E., Yu, E.D., Zajonc, D.M. 2.25 X-RAY DIFFRACTION 0.231 0.190 True 6puf H G NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 59.800 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-5'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.92 X-RAY DIFFRACTION 0.221 0.178 True 6d7g NA NA D E gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV8 TRDV1 IMMUNE SYSTEM 01/23/19 Structure of 5F3 TCR in complex with HLA-A2/MART-1 homo sapiens homo sapiens Roy, S., Adams, E.J. 2.75 X-RAY DIFFRACTION 0.237 0.211 True 1hxm NA NA C D gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV9 TRDV2 IMMUNE SYSTEM 06/20/01 Crystal Structure of a Human Vgamma9/Vdelta2 T Cell Receptor homo sapiens homo sapiens Allison, T.J., Winter, C.C., Fournie, J.J., Bonneville, M., Garboczi, D.N. 3.12 X-RAY DIFFRACTION 0.266 0.219 True 6vm8 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV19 TRAV8 NA NA IMMUNE SYSTEM 11/25/20 SILv44 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV) homo sapiens homo sapiens Smith, A.R., Baker, B.M. 2.41 X-RAY DIFFRACTION 0.221 0.187 True 6cxe D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-dihydroxy-8-oxo-8-[(6-phenylhexyl)amino]-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octan-2-yl]hexacosanamide EM4 CD1 A B 26.304 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/10/19 Structure of alpha-GSA[26,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus mus musculus mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.05 X-RAY DIFFRACTION 0.248 0.209 True 8jcb NA NA m n gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV5 TRDV1 IMMUNE SYSTEM 05/08/24 Vgamma5 Vdelta1 T cell receptor complex homo sapiens homo sapiens Xin, W., Huang, B., Chi, X., Xu, M., Zhang, Y., Li, X., Su, Q., Zhou, Q. 9.5 ELECTRON MICROSCOPY NA NA False 5nqk B A NA NA abTCR 0 P peptide melanoma antigen recognized by t-cells 1 NA MH1 H L 36.934 TRBV19 TRAV12 NA NA IMMUNE SYSTEM 05/30/18 human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Exertier, C., Reiser, J.-B., Lantez, V., Chouquet, A., Bonneville, M., Saulquin, X., Housset, D. 3.25 X-RAY DIFFRACTION 0.316 0.224 True 2pye E D NA NA abTCR 0 C peptide cancer/testis antigen 1b NA MH1 A B 65.755 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 09/25/07 Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry TCR Clone C5C1 Complexed with MHC homo sapiens homo sapiens homo sapiens homo sapiens Sami, M., Rizkallah, P.J., Dunn, S., Li, Y., Moysey, R., Vuidepot, A., Baston, E., Todorov, P., Molloy, P., Gao, F., Boulter, J.M., Jakobsen, B.K. 2.3 X-RAY DIFFRACTION 0.283 0.192 True 6pud E D NA NA abTCR 0 C Hapten 6-[(5-hydroxypentyl)amino]-5-[(E)-propylideneamino]pyrimidine-2,4(1H,3H)-dione OYD MR1 C F 58.538 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-5'OH-Pentyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.8 X-RAY DIFFRACTION 0.200 0.164 True 3tzv H G NA NA abTCR 0 C Hapten (4R,7R,18E)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOS-18-EN-1-AMINIUM 4-OXIDE LSC CD1 C D 22.983 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 04/25/12 Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Lopez-Sagaseta, J., Adams, E.J. 3.056 X-RAY DIFFRACTION 0.289 0.236 True 6eh6 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.78 X-RAY DIFFRACTION 0.224 0.194 True 2jcc M L NA NA abTCR 0 J peptide p1049 NA MH1 H I 65.045 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 10/09/07 AH3 recognition of mutant HLA-A2 W167A mus musculus mus musculus homo sapiens homo sapiens homo sapiens Miller, P., Benhar, Y.P., Biddison, W., Collins, E.J. 2.5 X-RAY DIFFRACTION 0.292 0.242 True 4p4k H G NA NA abTCR 0 NA NA NA NA MH2 E F 48.756 TRBV5 TRAV9 NA NA IMMUNE SYSTEM 07/16/14 Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity and auto immunity homo sapiens homo sapiens homo sapiens homo sapiens Clayton, G.M., Crawford, F., Kappler, J.W. 2.8 X-RAY DIFFRACTION 0.252 0.204 True 4pje H G NA NA abTCR 0 C Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 C D 60.988 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-B10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 1.95 X-RAY DIFFRACTION 0.197 0.171 True 6r2l E D NA NA abTCR 0 C peptide ser-leu-ser-lys-ile-leu-asp-thr-val NA MH1 A B 62.853 TRBV11 TRAV22 NA NA IMMUNE SYSTEM 02/26/20 NYBR1-A2-SLSKILDTV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sami, M. 2.3 X-RAY DIFFRACTION 0.265 0.214 True 7ufj H G NA NA abTCR 0 A Hapten ETHYL VANILLIN N36 MR1 A B 60.403 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 12/14/22 Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wang, C.J., Rossjohn, J., Le Nours, J. 2.5 X-RAY DIFFRACTION 0.238 0.181 True 2oi9 C B NA NA abTCR 0 Q peptide peptide (gln)(leu)(ser)(pro)(phe)(pro)(phe)(asp)(leu) NA MH1 A NA 48.240 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 04/24/07 Structure of the 2C/Ld/QL9 allogeneic complex mus musculus mus musculus mus musculus Garcia, K.C., Colf, L.A. 2.35 X-RAY DIFFRACTION 0.226 0.220 True 6fr4 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV21 NA NA IMMUNE SYSTEM 04/18/18 003 TCR Study of CDR Loop Flexibility homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.28 X-RAY DIFFRACTION 0.190 0.168 True 3qjf B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 Crystal structure of the 2B4 TCR mus musculus mus musculus Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 2.4 X-RAY DIFFRACTION 0.259 0.210 True 4pja H G NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 60.280 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.68 X-RAY DIFFRACTION 0.216 0.169 True 4mnh NA NA D C gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV4 TRDV1 IMMUNE SYSTEM 12/18/13 Structure of the DP10.7 TCR homo sapiens homo sapiens Luoma, A.M., Adams, E.J. 3.3 X-RAY DIFFRACTION 0.285 0.231 True 3kxf O M NA NA abTCR 0 S peptide peptide from trans-activator protein bzlf1 NA MH1 I J 69.543 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Tynan, F.E., Gras, S., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.291 0.213 True 3r8b H NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 6xc9 J I NA NA abTCR 0 NA NA NA NA MH2 F H 26.984 TRBV5 TRAV38 NA NA IMMUNE SYSTEM 07/14/21 Immune receptor complex homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Faridi, P., Lim, J.J., Ting, T.Y., Onwukwe, G., Bhattacharjee, P., Tresoldi, M.C.E., Cameron, J.F., La-Gruta, L.N., Purcell, W.A., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.4 X-RAY DIFFRACTION 0.219 0.185 True 5wlg E D NA NA abTCR 0 C peptide gap50 peptide NA MH1 A B 19.090 TRBV13 TRAV8 NA NA IMMUNE SYSTEM 11/15/17 Crystal Structure of H-2Db with the GAP501 peptide (SQL) mus musculus, homo sapiens mus musculus, homo sapiens plasmodium berghei mus musculus mus musculus Gras, S., Farenc, C., Josephs, T., Rossjohn, J. 2.1 X-RAY DIFFRACTION 0.249 0.218 True 3qjh D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 The crystal structure of the 5c.c7 TCR mus musculus mus musculus Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 1.9 X-RAY DIFFRACTION 0.256 0.225 True 8f5a D C NA NA abTCR 0 E peptide tw10 peptide NA MH1 A B 50.356 TRBV5 TRAV21 NA NA IMMUNE SYSTEM 05/22/24 Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10 homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Chatzileontiadou, D.S.M., Lobos, C.A., Gras, S. 1.95 X-RAY DIFFRACTION 0.237 0.202 True 7z50 E H NA NA abTCR 0 T peptide hybrid insulin peptide NA MH2 A B 42.070 TRBV16 TRAV5 NA NA IMMUNE SYSTEM 07/20/22 Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound to I-Ag7. mus musculus mus musculus mus musculus mus musculus mus musculus Lopez-Sagaseta, J., Erausquin, E. 2.65 X-RAY DIFFRACTION 0.261 0.221 True 1ac6 NA A NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV6 NA NA RECEPTOR 02/25/98 CRYSTAL STRUCTURE OF A VARIABLE DOMAIN MUTANT OF A T-CELL RECEPTOR ALPHA CHAIN mus musculus Li, H.-M., Mariuzza, R.A. 2.3 X-RAY DIFFRACTION 0.279 0.161 False 4c56 B A NA NA abTCR 0 C | F protein | peptide enterotoxin b | hemagglutinin NA | NA NA NA NA nan TRBV19 TRAV22 NA NA IMMUNE SYSTEM/TOXIN 07/23/14 X-ray structure of the complex between staphylococcal enterotoxin B, T cell receptor and major histocompatibility complex class II homo sapiens homo sapiens staphylococcus aureus | influenza a virus Rodstrom, K.E.J., Elbing, K., Lindkvist-Petersson, K. 2.9 X-RAY DIFFRACTION 0.251 0.233 True 4pji F E NA NA abTCR 0 NA NA NA NA MR1 C D 61.561 TRBV6 TRAV1 NA NA Immune System 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT C-C10 TCR homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.228 0.188 True 3arb D C NA NA abTCR 0 A Hapten N-{(1S,2S,3R)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYOCTYL}TETRACOSANAMIDE FEE CD1 A B 24.269 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 03/30/11 Ternary crystal structure of the NKT TCR-CD1d-alpha-galactosylceramide analogue-OCH mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wun, K.S., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.257 0.214 True 4pja F E NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 59.171 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.68 X-RAY DIFFRACTION 0.216 0.169 True 8dv4 E D NA NA abTCR 0 A | D | D | F Hapten | Hapten | Hapten | carbohydrate TETRACOSYL OCTADECANOATE | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL | N-ACETYL-D-GLUCOSAMINE CUY | PIE | PIE | NAG CD1 A B 83.531 TRBV6 TRAV9 NA NA IMMUNE SYSTEM 04/19/23 Crystal structure of the BC8B TCR-CD1b-PI complex homo sapiens homo sapiens homo sapiens | homo sapiens | homo sapiens homo sapiens homo sapiens Farquhar, R., Rossjohn, J., Shahine, A. 2.4 X-RAY DIFFRACTION 0.255 0.192 True 6bga D C NA NA abTCR 0 E peptide velcro peptide NA MH2 A B 36.298 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 07/18/18 2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide mus musculus mus musculus synthetic construct mus musculus mus musculus Gee, M.H., Sibener, L.V., Birnbaum, M.E., Jude, K.M., Garcia, K.C. 2.307 X-RAY DIFFRACTION 0.237 0.192 True 1lp9 F E NA NA abTCR 0 C peptide self-peptide p1049 NA MH1 A B 68.028 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 11/11/03 Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1 mus musculus mus musculus homo sapiens homo sapiens Buslepp, J., Wang, H., Biddison, W.E., Appella, E., Collins, E.J. 2 X-RAY DIFFRACTION 0.253 0.219 True 6mjj D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-({4-O-[(3,4-dichlorophenyl)methyl]-alpha-D-galactopyranosyl}oxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanamide JU4 CD1 A B 25.827 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxm (JJ290) /iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 1.93 X-RAY DIFFRACTION 0.216 0.184 True 7pbc B A NA NA abTCR 0 E peptide unknown NA MH1 C D 28.858 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide Simister, P.C., Border, E.C., Vieira, J.F., Pumphrey, N.J. 2.04 X-RAY DIFFRACTION 0.236 0.187 False 5u6q G B NA NA abTCR 0 NA NA NA NA MR1 A H 59.891 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-3-F-SA in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.222 0.182 True 1hxm NA NA E F gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV9 TRDV2 IMMUNE SYSTEM 06/20/01 Crystal Structure of a Human Vgamma9/Vdelta2 T Cell Receptor homo sapiens homo sapiens Allison, T.J., Winter, C.C., Fournie, J.J., Bonneville, M., Garboczi, D.N. 3.12 X-RAY DIFFRACTION 0.266 0.219 True 4l4t E D NA NA abTCR 0 C Hapten 2-AMINO-4-OXO-3,4-DIHYDROPTERIDINE-6-CARBALDEHYDE 6FP MR1 C F 62.054 TRBV6 TRAV1 NA NA Membrane Protein/Immune System 07/17/13 Structure of human MAIT TCR in complex with human MR1-6-FP homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S.B.G., Birkinshaw, R.W., Beddoe, T., Corbett, A.J., Liu, L., Miles, J.J., Meehan, B., Reantragoon, R., Sandoval-Romero, M.L., Sullivan, L.C., Brooks, A.G., Chen, Z., Fairlie, D.P., McCluskey, J., Rossjohn, J. 2 X-RAY DIFFRACTION 0.225 0.184 True 3skn H G NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 02/29/12 Crystal structure of the RL42 TCR unliganded homo sapiens homo sapiens Gras, S., Wilmann, P.G., Zhenjun, C., Hanim, H., Yu Chih, L., Kjer-Nielsen, L., Purcell, A.W., Burrows, S.R., Mccluskey, J., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.292 0.194 True 1nfd B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV12 NA NA COMPLEX (IMMUNORECEPTOR/IMMUNOGLOBULIN) 01/28/98 AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY mus musculus mus musculus Wang, J.-H., Lim, K., Smolyar, A., Teng, M.-K., Sacchittini, J., Reinherz, E.L. 2.8 X-RAY DIFFRACTION 0.309 0.243 True 3mv7 E D NA NA abTCR 0 C peptide hpvg peptide from epstein-barr nuclear antigen 1 NA MH1 A B 42.517 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of the TK3 TCR in complex with HLA-B*3501/HPVG homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Chen, Z., Miles, J.J., Liu, Y.C., Bell, M.J., Sullivan, L.C., Kjer-Nielsen, L., Brennan, R.M., Burrows, J.M., Neller, M.A., Khanna, R., Purcell, A.W., Brooks, A.G., McCluskey, J., Rossjohn, J., Burrows, S.R. 2 X-RAY DIFFRACTION 0.286 0.225 True 3e3q J I NA NA abTCR 0 K peptide ql9 peptide NA MH1 H NA 44.857 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 3owe K NA NA NA NA 0 H protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 4h1l H G NA NA abTCR 0 F peptide mimotope peptide NA MH2 D E 55.261 TRBV19 TRAV8 NA NA IMMUNE SYSTEM 11/14/12 TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy escherichia coli escherichia coli escherichia coli homo sapiens homo sapiens Kappler, J.W., Yin, L., Dai, S., Marrack, P. 3.3 X-RAY DIFFRACTION 0.285 0.263 True 2axj A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV19 NA NA NA IMMUNE SYSTEM 09/20/05 Crystal structures of T cell receptor beta chains related to rheumatoid arthritis homo sapiens Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y. 2.65 X-RAY DIFFRACTION 0.286 0.233 True 8vd2 E D NA NA abTCR 0 C peptide hybrid insulin peptide (hip; insc8-15-iapp23-29 ) NA MH2 A B 39.734 TRBV5 TRAV26 NA NA IMMUNE SYSTEM 08/07/24 Human TCR ET650-4 in complex with DQ8-InsC8-15-IAPP1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Lim, J.J., Loh, T.Y., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.9 X-RAY DIFFRACTION 0.259 0.221 True 5wkh E D NA NA abTCR 0 C peptide gts3 peptide NA MH1 A B 39.234 TRBV11 TRAV30 NA NA IMMUNE SYSTEM 09/20/17 D30 TCR in complex with HLA-A*11:01-GTS3 homo sapiens homo sapiens dengue virus 3 homo sapiens homo sapiens Gras, S., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.246 0.177 True 7l1d E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV9 TRAV12 NA NA IMMUNE SYSTEM 03/23/22 Crystal structure of human 21LT2-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide homo sapiens homo sapiens Ma, J., Baker, B.M. 3.11 X-RAY DIFFRACTION 0.250 0.198 True 8vcy E D NA NA abTCR 0 C peptide hybrid insulin peptide (hip; insc8-15-npy68-74) NA MH2 A B 33.199 TRBV5 TRAV26 NA NA IMMUNE SYSTEM 08/07/24 Human TCR A2.13 in complex with DQ8-InsC8-15NPY homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Lim, J.J., Loh, T.Y., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.6 X-RAY DIFFRACTION 0.225 0.185 True 5yxn B A NA NA abTCR 0 I peptide ns3 peptide NA MH1 C D 30.247 TRBV25 TRAV38 NA NA IMMUNE SYSTEM 12/12/18 A T cell receptor in complex with HLA-A0201 restricted Hepatitis C virus NS3 peptide (KLVALGINAV) homo sapiens homo sapiens hepatitis c virus homo sapiens homo sapiens Hui, F. 2.03 X-RAY DIFFRACTION 0.223 0.193 True 6rp9 E D NA NA abTCR 0 C peptide cancer/testis antigen 1 NA MH1 A B 67.267 TRBV7 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 3.12 X-RAY DIFFRACTION 0.250 0.223 True 5e9d J I NA NA abTCR 0 H peptide melanoma derived mart-1 peptide NA MH1 F G 36.540 TRBV6 TRAV12 NA NA PROTEIN BINDING 06/08/16 RD-1 Mart-1 High bound to Mart-1 decameric peptide (ELA) in complex with HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Singh, N.K., Baker, B.M. 2.51 X-RAY DIFFRACTION 0.232 0.180 True 2ak4 U T NA NA abTCR 0 S peptide ebv peptide lpeplpqgqltay NA MH1 Q R 68.113 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 10/11/05 Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide homo sapiens homo sapiens homo sapiens homo sapiens Tynan, F.E., Burrows, S.R., Buckle, A.M., Clements, C.S., Borg, N.A., Miles, J.J., Beddoe, T., Whisstock, J.C., Wilce, M.C., Silins, S.L., Burrows, J.M., Kjer-Nielsen, L., Konstenko, L., Purcell, A.W., McCluskey, J., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.278 0.246 True 5nmg J I NA NA abTCR 0 H peptide gag protein NA MH1 F G 55.019 TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR in complex with HLA A02 presenting SLYFNTIAVL homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.75 X-RAY DIFFRACTION 0.254 0.196 True 5w1w O N NA NA abTCR 0 M peptide leader peptide of hla class i histocompatibility antigen, aalpha chain NA MH1 K L 62.012 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.263 0.215 True 6uon H G NA NA abTCR 0 F peptide gly-ala-asp-gly-val-gly-lys-ser-ala-leu NA MH1 D E 68.717 TRBV10 TRAV12 NA NA IMMUNE SYSTEM 05/27/20 Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Sun, P.D., Sim, M.J.W. 3.5 X-RAY DIFFRACTION 0.294 0.252 True 6puj E D NA NA abTCR 0 C Hapten 6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione Q7S MR1 C F 59.465 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.92 X-RAY DIFFRACTION 0.194 0.163 True 4pjx F E NA NA abTCR 0 A | A Hapten | Hapten 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE B3P | 30W MR1 A B 56.053 TRBV6 TRAV1 NA NA Immune System 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT C-A11 TCR homo sapiens homo sapiens homo sapiens | homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.25 X-RAY DIFFRACTION 0.203 0.170 True 4ei5 H G NA NA abTCR 0 E | K Hapten | carbohydrate (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE | N-ACETYL-D-GLUCOSAMINE CIS | NAG CD1 E F 73.583 TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Crystal Structure of XV19 TCR in complex with CD1d-sulfatide C24:1 mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Patel, O., Gras, S., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.227 0.197 True 8shi H G NA NA abTCR 0 C peptide val-arg-ser-arg-arg-aba-leu-arg-leu NA MH1 A B 20.966 TRBV6 TRAV17 NA NA IMMUNE SYSTEM 06/28/23 Valpha3S1 Vbeta13S1 HLA C 0602 VRSRRCLRL homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Littler, D.R., Anand, S., Vivian, J.P., Rossjohn, J. 2.90002 X-RAY DIFFRACTION 0.291 0.235 True 5u6q E D NA NA abTCR 0 NA NA NA NA MR1 C F 62.303 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-3-F-SA in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.222 0.182 True 2q86 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/01/08 Structure of the mouse invariant NKT cell receptor Valpha14 mus musculus mus musculus Zajonc, D.M. 1.85 X-RAY DIFFRACTION 0.223 0.179 True 7f5k B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV7 NA NA IMMUNE SYSTEM 06/22/22 Crystal structure of TCR4-1 ectodomain mus musculus mus musculus Nagae, M., Yamasaki, S. 3.00003 X-RAY DIFFRACTION 0.311 0.225 True 3he6 D C NA NA abTCR 0 A carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 A B 23.813 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 07/28/09 Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta8.2 NKT TCR mus musculus mus musculus mus musculus mus musculus mus musculus Patel, O., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.298 0.234 True 6mss B A NA NA abTCR 0 C Hapten (2S)-2-(heptadecanoyloxy)-3-{[(10S)-10-methyloctadecanoyl]oxy}propyl alpha-D-glucopyranosiduronic acid SRV CD1 C D 21.169 TRBV13 TRAV4 NA NA IMMUNE SYSTEM 10/02/19 Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies mus musculus mus musculus mus musculus mus musculus mus musculus Sundararaj, S., Le Nours, J., Praveena, T., Rossjohn, J. 3 X-RAY DIFFRACTION 0.242 0.183 True 7k0z NA NA NA B NA 0 A protein t cell receptor mu chain NA NA NA NA nan NA NA NA NA IMMUNE SYSTEM 03/24/21 Marsupial T cell receptor Spl_157 monodelphis domestica monodelphis domestica Wegrecki, M., Kannan Sivaraman, K., Le Nours, J., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.286 0.257 True 4e42 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV22 NA NA IMMUNE SYSTEM 08/29/12 Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 homo sapiens homo sapiens Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A. 2.7 X-RAY DIFFRACTION 0.263 0.200 True 2apx A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 1.8 X-RAY DIFFRACTION 0.231 0.188 True 6amu E D NA NA abTCR 0 C peptide met-met-trp-asp-arg-gly-leu-gly-met-met NA MH1 A B 36.974 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 08/15/18 Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide MMWDRGLGMM homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Riley, T.P., Baker, B.M. 2.151 X-RAY DIFFRACTION 0.226 0.180 True 3of6 A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV7 NA NA NA IMMUNE SYSTEM 10/20/10 Human pre-T cell receptor crystal structure homo sapiens Pang, S.S. 2.8 X-RAY DIFFRACTION 0.240 0.175 True 3tzv B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 04/25/12 Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine homo sapiens homo sapiens Lopez-Sagaseta, J., Adams, E.J. 3.056 X-RAY DIFFRACTION 0.289 0.236 True 6rsy J I NA NA abTCR 0 H peptide arg-met-phe-pro-asn-ala-pro-tyr-leu NA MH1 F G 53.391 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/15/20 The complex between TCR a7b2 and human Class I MHC HLA-A0201-WT1 with the bound RMFPNAPYL peptide. homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Srikannathasan, V., Robinson, R.A. 2.95 X-RAY DIFFRACTION 0.291 0.251 True 4y4h H G NA NA abTCR 0 E Hapten (1R)-1,5-anhydro-1-{(1E,3S,4S,5R)-4,5-dihydroxy-3-[(8-phenyloctanoyl)amino]nonadec-1-en-1-yl}-D-galactitol 49X CD1 E F 26.050 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/GCK152/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Yu, E.D. 3.1 X-RAY DIFFRACTION 0.287 0.242 True 5u2v F E NA NA abTCR 0 C Hapten 2-HYDROXY-5-METHOXYBENZALDEHYDE 7WQ MR1 C D 62.213 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-HMB in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.221 0.179 True 5u17 G B NA NA abTCR 0 A Hapten 2,4-DIAMINOPTERIDINE-6-CARBALDEHYDE 7WP MR1 A H 58.987 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.15 X-RAY DIFFRACTION 0.224 0.180 True 5brz E D NA NA abTCR 0 C peptide glu-val-asp-pro-ile-gly-his-leu-tyr NA MH1 A B 57.904 TRBV5 TRAV21 NA NA IMMUNE SYSTEM 03/02/16 MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Raman, M.C.C., Rizkallah, P.J., Simmons, R., Donnellan, Z., Dukes, J., Bossi, G., LeProvost, G., Mahon, T., Hickman, E., LomaX, M., Oates, J., Hassan, N., Vuidepot, A., Sami, M., Cole, D.K., Jakobsen, B.K. 2.62 X-RAY DIFFRACTION 0.268 0.193 True 1l0y A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 04/03/02 T cell receptor beta chain complexed with superantigen SpeA soaked with zinc mus musculus Li, H., Sundberg, E.J., Mariuzza, R.A. 2.5 X-RAY DIFFRACTION 0.262 0.221 True 3tjh D C NA NA abTCR 0 B peptide p3a1 NA MH1 A NA 22.417 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 12/07/11 42F3-p3A1/H2-Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Adams, J.J., Kruse, A., Kranz, D.M., Garcia, K.C. 2.12 X-RAY DIFFRACTION 0.237 0.206 True 5d2n E D NA NA abTCR 0 I peptide asn-leu-val-pro-met-val-ala-thr-val NA MH1 A B 60.930 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 10/07/15 Crystal structure of C25-NLV-HLA-A2 complex homo sapiens homo sapiens cytomegalovirus homo sapiens homo sapiens Mariuzza, R.A., Yang, X. 2.099 X-RAY DIFFRACTION 0.253 0.204 True 3sda D C NA NA abTCR 0 A Hapten N-[(2S,3R)-1-(BETA-D-GALACTOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]TETRACOSANAMIDE GCY CD1 A B 24.345 TRBV19 TRAV11 NA NA IMMUNE SYSTEM 10/05/11 Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-beta-galactosylceramide mus musculus , homo sapiens mus musculus , homo sapiens mus musculus mus musculus mus musculus Clarke, A.J., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.312 0.272 True 4l8s B A NA NA abTCR 0 C protein beta-2-microglobulin, mhc class i-related protein NA NA NA NA nan TRBV6 TRAV1 NA NA IMMUNE SYSTEM 10/16/13 Crystal structure of a human Valpha7.2/Vbeta13.3 MAIT TCR in complex with bovine MR1 homo sapiens homo sapiens bos taurus Lopez-Sagaseta, J., Adams, E.J. 2.9 X-RAY DIFFRACTION 0.278 0.228 True 5u17 E D NA NA abTCR 0 C Hapten 2,4-DIAMINOPTERIDINE-6-CARBALDEHYDE 7WP MR1 C F 61.323 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.15 X-RAY DIFFRACTION 0.224 0.180 True 3h9s E D NA NA abTCR 0 C peptide tel1p peptide NA MH1 A B 36.494 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/12/10 The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.7 X-RAY DIFFRACTION 0.289 0.217 True 2aq3 C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.3 X-RAY DIFFRACTION 0.271 0.206 True 5e6i H G NA NA abTCR 0 K peptide matrix protein 1 NA MH1 I J 66.310 TRBV27 TRAV35 NA NA IMMUNE SYSTEM 10/19/16 Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Gao, M., Mariuzza, R. 4 X-RAY DIFFRACTION 0.338 0.259 True 3dx9 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV26 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of the DM1 TCR at 2.75A homo sapiens homo sapiens Archbold, J.K., Macdonald, W.A., Gras, S., Rossjohn, J. 2.75 X-RAY DIFFRACTION 0.263 0.204 True 5e6i B A NA NA abTCR 0 E peptide matrix protein 1 NA MH1 C D 63.730 TRBV27 TRAV35 NA NA IMMUNE SYSTEM 10/19/16 Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Gao, M., Mariuzza, R. 4 X-RAY DIFFRACTION 0.338 0.259 True 8wte D C NA NA abTCR 0 G peptide kras-g12v nonamer peptide NA MH1 E F 64.827 TRBV2 TRAV7 NA NA IMMUNE SYSTEM 05/01/24 Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Zhang, M.Y., Luo, L.J., Xu, W., Guan, F.H., Wang, X.Y., Zhu, P., Zhang, J.H., Zhou, X.Y., Wang, F., Ye, S. 2.17 X-RAY DIFFRACTION 0.216 0.171 True 2apv A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the G17E/A52V/S54N/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 1.9 X-RAY DIFFRACTION 0.230 0.187 True 1mwa B A NA NA abTCR 0 P peptide dev8 NA MH1 H L 22.774 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/27/02 2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX mus musculus mus musculus mus musculus mus musculus Luz, J.G., Huang, M.D., Garcia, K.C., Rudolph, M.G., Teyton, L., Wilson, I.A. 2.4 X-RAY DIFFRACTION 0.313 0.284 True 4elm F E NA NA abTCR 0 C Hapten (2S,3R,4E)-2-AMINO-3-HYDROXYOCTADEC-4-EN-1-YL 3-O-SULFO-BETA-D-GALACTOPYRANOSIDE SGF CD1 C D 72.834 TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Crystal structure of the mouse CD1d-lysosulfatide-Hy19.3 TCR complex mus musculus mus musculus mus musculus mus musculus mus musculus Girardi, E., Maricic, I., Wang, J., Mac, T.T., Iyer, P., Kumar, V., Zajonc, D.M. 3.48 X-RAY DIFFRACTION 0.265 0.209 True 7m72 D C NA NA abTCR 0 A Hapten (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxy-15-methylhexadecan-2-yl]-3-hydroxyheptadecanamide QOD CD1 A B 27.218 TRBV13 TRAV11 NA NA LIPID BINDING PROTEIN/IMMUNE SYSTEM 11/10/21 MHC-like protein complex structure mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Thirunavukkarasu, P., Le Nours, J., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.227 0.184 True 7ryn NA NA D C gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV4 TRDV1 IMMUNE SYSTEM 05/18/22 CD1a-sulfatide-gdTCR complex homo sapiens homo sapiens Wegrecki, M., Le Nours, J., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.268 0.232 True 4prp E D NA NA abTCR 0 C peptide epstein-barr nuclear antigen 1 NA MH1 A B 42.431 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 04/16/14 Crystal structure of TK3 TCR-HLA-B*35:01-HPVG-Q5 complex homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Yu Chih, L., Rossjohn, J., Gras, S. 2.5 X-RAY DIFFRACTION 0.229 0.180 True 4lcc B A NA NA abTCR 0 C | C protein | Hapten beta-2-microglobulin, mhc class i-related protein | 1-deoxy-1-[6-(hydroxymethyl)-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl]-D-arabinitol NA | 1XL NA NA NA nan TRBV6 TRAV1 NA NA IMMUNE SYSTEM 10/16/13 Crystal structure of a human MAIT TCR in complex with a bacterial antigen bound to humanized bovine MR1 homo sapiens homo sapiens bos taurus | bos taurus Lopez-Sagaseta, J., Adams, E.J. 3.263 X-RAY DIFFRACTION 0.312 0.257 True 3owe M NA NA NA NA 0 B protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 3utp E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV12 TRAV12 NA NA IMMUNE SYSTEM 01/25/12 1E6 TCR specific for HLA-A*0201-ALWGPDPAAA homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M. 2.574 X-RAY DIFFRACTION 0.291 0.230 True 5w1w J I NA NA abTCR 0 H peptide leader peptide of hla class i histocompatibility antigen, aalpha chain NA MH1 F G 69.315 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.263 0.215 True 7zt9 E D NA NA abTCR 0 NA NA NA NA MR1 A B 60.202 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex in human MR1 bound to 4FBA homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Srikannathasan, V., Robinson, R.A. 2.13 X-RAY DIFFRACTION 0.244 0.196 True 5ivx F E NA NA abTCR 0 P peptide p18-i10 NA MH1 A B 30.150 TRBV29 TRAV14 NA NA IMMUNE SYSTEM 03/29/17 Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex mus musculus mus musculus homo sapiens mus musculus mus musculus Natarajan, K., Jiang, J., Margulies, D. 2.1 X-RAY DIFFRACTION 0.220 0.180 True 4y1a E D NA NA abTCR 0 C peptide insulin NA MH2 A B 41.459 TRBV6 TRAV29 NA NA IMMUNE SYSTEM 09/23/15 immune complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Beringer, D.X., Vivian, J.P., Reid, H.H., Rossjohn, J. 4 X-RAY DIFFRACTION 0.283 0.225 True 5nmf E D NA NA abTCR 0 C peptide gag protein NA MH1 A B 51.143 TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR in complex with HLA A02 presenting SLYNTIATL homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.89 X-RAY DIFFRACTION 0.255 0.193 True 6eh8 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 HA1.7 Human T-Cell Receptor specific for Influenza virus epitope PKYVKQNTLKLAT presented by Human Leukocyte Antigen HLA-DR0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 2.51 X-RAY DIFFRACTION 0.296 0.223 True 6xc9 E D NA NA abTCR 0 NA NA NA NA MH2 A C 27.060 TRBV5 TRAV38 NA NA IMMUNE SYSTEM 07/14/21 Immune receptor complex homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Faridi, P., Lim, J.J., Ting, T.Y., Onwukwe, G., Bhattacharjee, P., Tresoldi, M.C.E., Cameron, J.F., La-Gruta, L.N., Purcell, W.A., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.4 X-RAY DIFFRACTION 0.219 0.185 True 2cde F E NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA CELL RECEPTOR 03/07/06 Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR homo sapiens homo sapiens Gadola, S.D., Koch, M., Marles-Wright, J., Lissin, N.M., Sheperd, D., Matulis, G., Harlos, K., Villiger, P.M., Stuart, D.I., Jakobsen, B.K., Cerundolo, V., Jones, E.Y. 3.5 X-RAY DIFFRACTION 0.3504 0.2830 True 7pdw B A NA NA abTCR 0 E peptide unknown NA MH1 C D 31.330 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/08/09 Crystal structure of parent TCR (728) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide Simister, P.C., Border, E.C., Vieira, J.F., Pumphrey, N.J. 1.82 X-RAY DIFFRACTION 0.229 0.201 False 2iam D C NA NA abTCR 0 P peptide 15-mer peptide from triosephosphate isomerase NA MH2 A B 43.401 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.279 0.207 True 6u3o H G NA NA abTCR 0 I peptide peptide NA MH2 E F 47.510 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 12/18/19 JR51 DQ2-p.aeru-alpha2a complex homo sapiens homo sapiens pseudomonas aeruginosa homo sapiens homo sapiens Petersen, J., Rossjohn, J. 2.743 X-RAY DIFFRACTION unknown unknown True 3tvm H G NA NA abTCR 0 E Hapten N-[(2S,3R)-10-[(1R,2R)-2-DECYLCYCLOPROPYL]-1-(ALPHA-D-GALACTOPYRANOSYLOXY)-3-HYDROXYDECAN-2-YL]HEXACOSANAMIDE 07P CD1 E F 26.967 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 02/01/12 Structure of the mouse CD1d-SMC124-iNKT TCR complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Girardi, E., Li, Y., Zajonc, D.M. 2.8 X-RAY DIFFRACTION 0.273 0.224 True 6v0y E D NA NA abTCR 0 C peptide fibrinogen beta 72,74cit69-81 NA GB B NA nan TRBV4 TRAV6 NA NA IMMUNE SYSTEM 11/25/20 immune receptor complex mus musculus mus musculus homo sapiens homo sapiens Lim, J.J., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.247 0.220 True 3r8b B NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 3utt J I NA NA abTCR 0 H peptide insulin NA MH1 F G 41.596 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 01/25/12 1E6-A*0201-ALWGPDPAAA Complex, Triclinic homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M., Rossjohn, J., Gras, S. 2.6 X-RAY DIFFRACTION 0.274 0.195 True 5w1v J I NA NA abTCR 0 H peptide vmaprtlil peptide from cmv gpul40 NA MH1 F G 69.083 TRBV9 TRAV35 NA NA IMMUNE SYSTEM 10/04/17 Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex homo sapiens homo sapiens human herpesvirus 5 strain ad169 homo sapiens homo sapiens Gras, S., Walpole, N., Farenc, C., Rossjohn, J. 3.31 X-RAY DIFFRACTION 0.268 0.225 True 3byt A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN 05/12/09 A complex between a variant of staphylococcal enterotoxin C3 and the variable domain of the murine T cell receptor beta chain 8.2 mus musculus Cho, S., Eric, J.S. 2.3 X-RAY DIFFRACTION 0.278 0.226 True 8enh O N NA NA abTCR 0 M peptide nucleoprotein np7 epitope NA MH1 K L 42.123 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP7 epitope from 2002 H3N2 influenza strain homo sapiens homo sapiens influenza a virus (strain a/2002/h3n2) homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.50003 X-RAY DIFFRACTION 0.230 0.191 True 5nme J I NA NA abTCR 0 H peptide gag protein NA MH1 F G 52.367 TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR in complex with HLA A02 presenting SLYNTVATL homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.94 X-RAY DIFFRACTION 0.263 0.196 True 3e3q F C NA NA abTCR 0 G peptide ql9 peptide NA MH1 B NA 45.261 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 7f5k D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV7 NA NA IMMUNE SYSTEM 06/22/22 Crystal structure of TCR4-1 ectodomain mus musculus mus musculus Nagae, M., Yamasaki, S. 3.00003 X-RAY DIFFRACTION 0.311 0.225 True 5fka B A NA NA abTCR 0 C protein staphylococcal enterotoxin e NA NA NA NA nan TRBV7 TRAV22 NA NA IMMUNE SYSTEM 05/25/16 Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor homo sapiens homo sapiens staphylococcus aureus Rodstrom, K.E.J., Regenthal, P., Lindkvist-Petersson, K. 2.4 X-RAY DIFFRACTION 0.2416 0.2119 True 6v80 I H NA NA abTCR 0 F | J carbohydrate | protein N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE | nanobody vhh id12 AGH | NA CD1 F G 31.010 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 09/16/20 Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12 homo sapiens homo sapiens homo sapiens | lama glama homo sapiens homo sapiens Shahine, A., Rossjohn, J. 3.53 X-RAY DIFFRACTION 0.254 0.195 True 6lir B A NA NA abTCR 0 NA NA NA NA NA NA NA nan NA NA NA NA IMMUNE SYSTEM 11/18/20 crystal structure of chicken TCR for 2.0 gallus gallus gallus gallus Zhang, L., Xia, C. 2.091 X-RAY DIFFRACTION 0.236 0.205 True 6mwr NA NA D C gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV9 TRDV1 IMMUNE SYSTEM 12/18/19 Recognition of MHC-like molecule homo sapiens homo sapiens Le Nours, J., Rossjohn, J. 3.3 X-RAY DIFFRACTION 0.261 0.238 True 6w9v E D NA NA abTCR 0 NA NA NA NA MR1 C F 56.798 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 08/05/20 Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H without ligand homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.95 X-RAY DIFFRACTION 0.200 0.160 True 7t2c E D NA NA abTCR 0 C peptide pneumolysin-derived peptide NA MH2 A B 51.719 TRBV20 TRAV4 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the B5 TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.257 0.211 True 4n0c D C NA NA abTCR 0 B peptide pcpe3 NA MH1 A NA 45.432 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 08/19/15 42F3 TCR pCPE3/H-2Ld complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 2.9 X-RAY DIFFRACTION 0.247 0.192 True 2p1y G g NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV14 NA NA IMMUNE SYSTEM 02/05/08 1.B2.D9, a bispecific alpha/beta TCR mus musculus McBeth, C., Pizarro, J.C., Strong, R.K. 2.42 X-RAY DIFFRACTION 0.254 0.181 True 2ian J I NA NA abTCR 0 H peptide 15-mer peptide from triosephosphate isomerase NA MH2 F G 42.811 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.296 0.221 True 6u3o B A NA NA abTCR 0 J peptide peptide NA MH2 C D 47.849 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 12/18/19 JR51 DQ2-p.aeru-alpha2a complex homo sapiens homo sapiens pseudomonas aeruginosa homo sapiens homo sapiens Petersen, J., Rossjohn, J. 2.743 X-RAY DIFFRACTION unknown unknown True 2eyr B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 03/21/06 A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition homo sapiens homo sapiens Kjer-Nielsen, L., Borg, N.A. 2.4 X-RAY DIFFRACTION 0.271 0.230 True 2aq3 A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mus musculus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2.3 X-RAY DIFFRACTION 0.271 0.206 True 3owe A NA NA NA NA 0 N protein enterotoxin seg NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 11/03/10 Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain mus musculus staphylococcus aureus Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L. 2.6 X-RAY DIFFRACTION 0.261 0.211 True 2pxy B A NA NA abTCR 0 P peptide myelin basic protein (mbp)-peptide NA MH2 C D 47.201 TRBV13 TRAV6 NA NA IMMUNE SYSTEM 10/09/07 Crystal structures of immune receptor complexes mus musculus mus musculus mus musculus mus musculus Feng, D., Bond, C.J., Ely, L.K., Garcia, K.C. 2.23 X-RAY DIFFRACTION 0.253 0.218 True 3vxt D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV27 TRAV12 NA NA IMMUNE SYSTEM 10/23/13 T36-5 TCR specific for HLA-A24-Nef134-10 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.5 X-RAY DIFFRACTION 0.271 0.230 True 4p2r E D NA NA abTCR 0 C peptide 5c1 peptide NA MH2 A B 31.920 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.295 X-RAY DIFFRACTION 0.243 0.212 True 4ww1 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV21 NA NA IMMUNE SYSTEM 02/03/16 Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8 and Beta Chain-TRBV7-8 homo sapiens homo sapiens Le Nours, J., Praveena, T., Pellicci, D.G., Lim, R.T., Besra, G., Howell, A.R., Godfrey, D.I., Rossjohn, J., Uldrich, A.P. 1.38 X-RAY DIFFRACTION 0.213 0.193 True 5c08 J I NA NA abTCR 0 H peptide marker peptide NA MH1 F G 45.257 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in Complex with HLA-A0e carrying RQWGPDPAAV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 2.332 X-RAY DIFFRACTION 0.272 0.206 True 7ndt E D NA NA abTCR 0 C peptide unknown NA MH1 A B 36.802 TRBV14 TRAV26 NA NA IMMUNE SYSTEM 01/08/09 UL40:01 TCR in complex with HLA-E with a non-natural amino acid Pengelly, R.J., Robinson, R.A. 2.999 X-RAY DIFFRACTION 0.269 0.221 False 3vxu J I NA NA abTCR 0 H peptide 10-mer peptide from protein nef NA MH1 F G nan TRBV27 TRAV12 NA NA IMMUNE SYSTEM 10/23/13 The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Shimizu, A., Fukai, S., Yamagata, A., Iwamoto, A. 2.7 X-RAY DIFFRACTION 0.323 0.272 True 5swz T S NA NA abTCR 0 R peptide influenza np366 epitope NA MH1 P Q 53.129 TRBV17 TRAV14 NA NA IMMUNE SYSTEM 10/05/16 Crystal Structure of NP1-B17 TCR-H2Db-NP complex mus musculus mus musculus unidentified influenza virus mus musculus mus musculus Gras, S., Del Campo, C.M., Farenc, C., Josephs, T.M., Rossjohn, J. 2.65 X-RAY DIFFRACTION 0.249 0.226 True 4g9f E D NA NA abTCR 0 C peptide gag protein NA MH1 A B 41.591 TRBV6 TRAV14 NA NA IMMUNE SYSTEM 03/20/13 Crystal Structure of C12C TCR-HLAB2705-KK10-L6M homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Gras, S., Wilmann, P.G., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.238 0.187 True 3qib D C NA NA abTCR 0 P peptide mcc peptide NA MH2 A B 36.287 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 04/27/11 Crystal structure of the 2B4 TCR in complex with MCC/I-Ek mus musculus homo sapiens manduca sexta mus musculus mus musculus Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C. 2.7 X-RAY DIFFRACTION 0.246 0.221 True 4g8g E D NA NA abTCR 0 C peptide p24 NA MH1 A B 41.186 TRBV6 TRAV14 NA NA IMMUNE SYSTEM 03/20/13 Crystal Structure of C12C TCR-HA B2705-KK10 homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Gras, S., Wilmann, P.G., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.257 0.178 True 7t2b E D NA NA abTCR 0 C peptide pneumolysin-derived peptide NA MH2 A B 36.420 TRBV6 TRAV17 NA NA IMMUNE SYSTEM 12/28/22 Crystal structure of the 5F TCR in complex with HLA-DP4-Ply homo sapiens homo sapiens streptococcus pneumoniae homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.250 0.216 True 4ei6 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Structure of XV19 Valpha1-Vbeta16 Type-II Natural Killer T cell receptor mus musculus, homo sapiens mus musculus, homo sapiens Patel, O., Rossjohn, J. 1.6 X-RAY DIFFRACTION 0.241 0.208 True 7n2o F D NA NA abTCR 0 C peptide yeih protein NA MH1 A B 21.056 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 AS4.2-YEIH-HLA*B27 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.3 X-RAY DIFFRACTION 0.267 0.221 True 4p2q O N NA NA abTCR 0 M peptide 5c2 peptide NA MH2 K L 32.395 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.3 X-RAY DIFFRACTION 0.236 0.188 True 3vwj D C NA NA abTCR 0 A Hapten (11Z,14E)-N-[(2S,3S,4R)-1-(ALPHA-D-GALACTOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]ICOSA-11,14-DIENAMIDE DB3 CD1 A B 30.774 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 10/03/12 Ternary crystal structure of the human NKT TCR-CD1d-C20:2 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wun, K.S., Rossjohn, J. 3.093 X-RAY DIFFRACTION 0.292 0.228 True 6pui G B NA NA abTCR 0 A Hapten 6-[(4-hydroxybutyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione Q7P MR1 A H 61.357 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-4'OH-Butyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.96 X-RAY DIFFRACTION 0.200 0.157 True 8i5c d c NA NA abTCR 0 b peptide unknown NA MH1 Z a 47.592 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 False 5tez J I NA NA abTCR 0 C peptide gly-ile-leu-gly-phe-val-phe-thr-leu NA MH1 A B 34.416 TRBV27 TRAV13 NA NA IMMUNE SYSTEM 09/27/17 TCR F50 recgonizing M1-HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Yang, X., Mariuzza, R.A. 1.7 X-RAY DIFFRACTION 0.224 0.190 True 6xqq B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV12 NA NA IMMUNE SYSTEM 08/19/20 Structure of human D462-E4 TCR homo sapiens homo sapiens Awad, W., Rossjohn, J. 2.68 X-RAY DIFFRACTION 0.223 0.194 True 5fk9 B A NA NA abTCR 0 C protein enterotoxin type a NA NA NA NA nan TRBV7 TRAV22 NA NA IMMUNE SYSTEM 05/25/16 Crystal structure of staphylococcal enterotoxin A F47A mutant in complex with a T cell receptor homo sapiens homo sapiens staphylococcus aureus Rodstrom, K.E.J., Regenthal, P., Lindkvist-Petersson, K. 3.1 X-RAY DIFFRACTION 0.2908 0.2571 True 4qrp E D NA NA abTCR 0 C peptide ns3-4a protein NA MH1 A B 49.048 TRBV11 TRAV9 NA NA IMMUNE SYSTEM 11/12/14 Crystal Structure of HLA B*0801 in complex with HSKKKCDEL and DD31 TCR homo sapiens homo sapiens hepatitis c virus homo sapiens homo sapiens Gras, S., Berry, R., Lucet, I.S., Rossjohn, J. 2.9 X-RAY DIFFRACTION 0.248 0.207 True 8jbv NA NA M N gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV5 TRDV1 IMMUNE SYSTEM 05/08/24 Extracellular domain of gamma delta TCR homo sapiens homo sapiens Xin, W., Chi, X., Huang, B., Su, Q., Zhou, Q. 3.02 ELECTRON MICROSCOPY NA NA True 3d39 E D NA NA abTCR 0 C peptide modified htlv-1 tax (y5(4fluoro)f) peptide NA MH1 A B 36.650 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 06/16/09 The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(4-fluoroPhenylalanine)) peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Clemens, J.R., Baker, B.M. 2.81 X-RAY DIFFRACTION 0.269 0.201 True 6zkw E D NA NA abTCR 0 C peptide enoyl-[acyl-carrier-protein] reductase [nadh] NA MH1 A B 60.156 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 01/26/22 Crystal structure of InhA:01 TCR in complex with HLA-E bound to InhA (53-61) homo sapiens homo sapiens mycobacterium tuberculosis h37rv homo sapiens homo sapiens Srikannathasan, V., Karuppiah, V., Robinson, R.A. 2.26 X-RAY DIFFRACTION 0.287 0.243 True 4ftv E D NA NA abTCR 0 C peptide protein tax-1 NA MH1 A B 34.205 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/03/13 The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide homo sapiens homo sapiens human t-cell lymphotropic virus type 1 (africanisolate) homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.74 X-RAY DIFFRACTION 0.260 0.216 True 6c68 D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV12 NA NA IMMUNE SYSTEM 01/30/19 MHC-independent t cell receptor A11 mus musculus mus musculus Lu, J., Van Laethem, F., Saba, I., Chu, J., Bhattacharya, A., Love, N.C., Tikhonova, A., Radaev, S., Sun, X., Ko, A., Arnon, T., Shifrut, E., Friedman, N., Weng, N., Singer, A., Sun, P.D. 2.59 X-RAY DIFFRACTION 0.258 0.202 True 6px6 E D NA NA abTCR 0 C peptide dq2.2-glut-l1 NA MH2 A B 30.442 TRBV7 TRAV21 NA NA IMMUNE SYSTEM 01/15/20 HLA-TCR complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Ting, Y.T., Reid, H.H., Rossjohn, J. 3 X-RAY DIFFRACTION 0.257 0.205 True 6v1a E D NA NA abTCR 0 C peptide fibrinogen beta 74cit69-81 NA MH2 A B 24.853 TRBV4 TRAV6 NA NA IMMUNE SYSTEM 11/25/20 immune receptor complex mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lim, J.J., Rossjohn, J. 2.29 X-RAY DIFFRACTION 0.214 0.187 True 7pb2 J I NA NA abTCR 0 H peptide kras g12d peptide (vvvgadgvgk) NA MH1 F G 44.494 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 07/20/22 Crystal structure of JDI TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK) homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Karuppiah, V., Robinson, R.A. 3.41 X-RAY DIFFRACTION 0.254 0.228 True 8t4z D C NA NA abTCR 0 A Hapten N-[(2R,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide Y73 CD1 A B 25.807 TRBV13 TRAV11 NA NA LIPID BINDING PROTEIN 08/07/24 T-cell receptor and lipid complex structure mus musculus mus musculus, homo sapiens mus musculus mus musculus mus musculus Praveena, T., Rossjohn, J. 2.691 X-RAY DIFFRACTION 0.265 0.193 True 8vz8 D C NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 57.191 TRBV13 TRAV1 NA NA IMMUNE SYSTEM 04/10/24 Crystal structure of mouse MAIT M2B TCR-MR1-5-OP-RU complex mus musculus mus musculus mus musculus mus musculus mus musculus Ciacchi, L., Rossjohn, J., Awad, W. 3.45 X-RAY DIFFRACTION 0.280 0.256 True 4ozi F E NA NA abTCR 0 I peptide deamidated gliadin-alpha1 peptide NA GA C NA nan TRBV20 TRAV4 NA NA IMMUNE SYSTEM 04/16/14 S2 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.243 0.213 True 7z50 F G NA NA abTCR 0 W peptide hybrid insulin peptide NA MH2 C D 41.089 TRBV16 TRAV5 NA NA IMMUNE SYSTEM 07/20/22 Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound to I-Ag7. mus musculus mus musculus mus musculus mus musculus mus musculus Lopez-Sagaseta, J., Erausquin, E. 2.65 X-RAY DIFFRACTION 0.261 0.221 True 1u3h F E NA NA abTCR 0 I peptide myelin basic protein (mbp)-peptide NA MH2 G H 40.041 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 05/17/05 Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A mus musculus mus musculus synthetic construct mus musculus mus musculus Maynard, J., Petersson, K., Wilson, D.H., Adams, E.J., Blondelle, S.E., Boulanger, M.J., Wilson, D.B., Garcia, K.C. 2.42 X-RAY DIFFRACTION 0.274 0.232 True 6dfq F E NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV1 TRAV10 NA NA IMMUNE SYSTEM 04/17/19 mouse diabetogenic TCR I.29 mus musculus mus musculus Wang, Y., Dai, S. 2.6 X-RAY DIFFRACTION 0.253 0.220 True 4p2q E D NA NA abTCR 0 C peptide 5c2 peptide NA MH2 A B 31.741 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.3 X-RAY DIFFRACTION 0.236 0.188 True 7n4k E D NA NA abTCR 0 C peptide peptide from polymerase acidic protein NA MH1 A NA 41.469 TRBV29 TRAV21 NA NA IMMUNE SYSTEM 07/20/22 6218 TCR in complex with H2-Db PA 224 mus musculus, homo sapiens mus musculus, homo sapiens influenza a virus mus musculus Szeto, C., Gras, S. 1.85 X-RAY DIFFRACTION 0.214 0.186 True 1kj2 B A NA NA abTCR 0 P peptide naturally processed octapeptide pkb1 NA MH1 H L 31.004 TRBV1 TRAV14 NA NA IMMUNE SYSTEM 03/27/02 Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex mus musculus mus musculus mus musculus mus musculus Reiser, J.-B., Gregoire, C., Darnault, C., Mosser, T., Guimezanes, A., Schmitt-Verhulst, A.-M., Fontecilla-Camps, J.C., Mazza, G., Malissen, B., Housset, D. 2.71 X-RAY DIFFRACTION 0.278 0.220 True 7ea6 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV11 TRAV12 NA NA IMMUNE SYSTEM 10/13/21 Crystal structure of TCR-017 ectodomain homo sapiens homo sapiens Nagae, M., Yamasaki, S. 2.18 X-RAY DIFFRACTION 0.276 0.222 True 4ozh F E NA NA abTCR 0 I peptide gliadin-alpha2 peptide NA MH2 C D 32.047 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/16/14 S16 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.243 0.226 True 6mjq D C NA NA abTCR 0 A Hapten N-{(2S,3S,4R)-3,4-dihydroxy-1-[(4-O-{[4-(trifluoromethyl)phenyl]methyl}-alpha-D-galactopyranosyl)oxy]octadecan-2-yl}hexacosanamide JUD CD1 A B 25.911 TRBV13 TRAV11 NA NA immune system/inhibitor 01/09/19 Crystal structure of the mCD1d/xxp (JJ295) /iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 3 X-RAY DIFFRACTION 0.258 0.215 True 4elk B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV3 TRAV7 NA NA IMMUNE SYSTEM 07/25/12 Crystal structure of the Hy19.3 type II NKT TCR mus musculus mus musculus Girardi, E., Maricic, I., Wang, J., Mac, T.T., Iyer, P., Kumar, V., Zajonc, D.M. 2.1 X-RAY DIFFRACTION 0.227 0.188 True 2ckb B A NA NA abTCR 0 P peptide dev8 peptide NA MH1 H L 22.691 TRBV13 TRAV9 NA NA MAJOR HISTOCOMPATIBILITY COMPLEX 04/29/98 STRUCTURE OF THE 2C/KB/DEV8 COMPLEX mus musculus mus musculus mus musculus mus musculus Garcia, K.C., Degano, M., Wilson, I.A. 3 X-RAY DIFFRACTION 0.322 0.221 True 8dfw NA NA D G gdTCR 0 NA NA NA NA NA NA NA nan NA NA TRGV9 TRDV2 IMMUNE SYSTEM 07/05/23 Crystal Structure of Human BTN2A1 in Complex With Vgamma9-Vdelta2 T Cell Receptor homo sapiens homo sapiens Fulford, T.S., Soliman, C., Castle, R.G., Rigau, M., Ruan, Z., Dolezal, O., Seneviratna, R., Brown, H.G., Hanssen, E., Hammet, A., Li, S., Redmond, S.J., Chung, A., Gorman, M.A., Parker, M.W., Patel, O., Peat, T.S., Newman, J., Behren, A., Gherardin, N.A., Godfrey, D.I., Uldrich, A.P. 2.1 X-RAY DIFFRACTION 0.287 0.261 True 2z31 B A NA NA abTCR 0 P peptide myelin basic protein (mbp)-peptide NA MH2 C D 47.055 TRBV13 TRAV6 NA NA IMMUNE SYSTEM 10/09/07 Crystal structure of immune receptor complex mus musculus mus musculus mus musculus mus musculus Feng, D., Bond, C.J., Ely, L.K., Garcia, K.C. 2.7 X-RAY DIFFRACTION 0.287 0.235 True 6mkr B A NA NA abTCR 0 NA NA NA NA MH2 C D 40.902 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 07/03/19 5287 TCR bound to IAb Padi4 mus musculus mus musculus mus musculus mus musculus Stadinski, B.D., Blevins, S.J., Huseby, E.S. 3.355 X-RAY DIFFRACTION 0.269 0.228 True 7sg1 E D NA NA abTCR 0 C peptide dq2-glia-alpha1a peptide NA MH2 A B 37.198 TRBV29 TRAV4 NA NA IMMUNE SYSTEM 02/23/22 XPA5 TCR in complex with HLA-DQ2-alpha1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.258 0.217 True 2esv E D NA NA abTCR 0 P peptide vmaprtlil peptide from cmv gpul40 NA MH1 A B 39.357 TRBV14 TRAV26 NA NA IMMUNE SYSTEM 03/21/06 Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex homo sapiens homo sapiens homo sapiens homo sapiens Hoare, H.L., Rossjohn, J. 2.6 X-RAY DIFFRACTION 0.292 0.214 True 3dxa J I NA NA abTCR 0 H peptide ebv decapeptide epitope NA MH1 F G 60.428 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of the DM1 TCR in complex with HLA-B*4405 and decamer EBV antigen homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Macdonald, W.A., Gras, S., Rossjohn, J. 3.5 X-RAY DIFFRACTION 0.330 0.286 True 5euo H G NA NA abTCR 0 I peptide matrix protein 1 NA MH1 C D 66.140 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 11/23/16 PF6-M1-HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Yang, X. 2.1 X-RAY DIFFRACTION 0.281 0.229 True 5u2v H G NA NA abTCR 0 A Hapten 2-HYDROXY-5-METHOXYBENZALDEHYDE 7WQ MR1 A B 59.409 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-HMB in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.221 0.179 True 3byt C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN 05/12/09 A complex between a variant of staphylococcal enterotoxin C3 and the variable domain of the murine T cell receptor beta chain 8.2 mus musculus Cho, S., Eric, J.S. 2.3 X-RAY DIFFRACTION 0.278 0.226 True 4grm D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 07/10/13 The crystal structure of the high affinity TCR A6 homo sapiens homo sapiens Borbulevych, O.Y., Scott, D.R., Baker, B.M. 2 X-RAY DIFFRACTION 0.295 0.234 True 1l0y C NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 04/03/02 T cell receptor beta chain complexed with superantigen SpeA soaked with zinc mus musculus Li, H., Sundberg, E.J., Mariuzza, R.A. 2.5 X-RAY DIFFRACTION 0.262 0.221 True 2ij0 E NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV20 NA NA NA PROTEIN BINDING 02/20/07 Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1 homo sapiens Moza, B., Varma, A.K., Buonpane, R.A., Zhu, P., Herfst, C.A., Nicholson, M.J., Wilbuer, A.K., Nulifer, S., Wucherpfenning, K.W., McCormick, J.K., Kranz, D.M., Sundberg, E.J. 2.25 X-RAY DIFFRACTION 0.252 0.242 True 5hhm E D NA NA abTCR 0 C peptide m1-f5l, gilglvftl NA MH1 A B 63.896 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 03/23/16 Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Gras, S., Josephs, T.M., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.289 0.216 True 4pjc F E NA NA abTCR 0 A | A Hapten | Hapten 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL B3P | 2LJ MR1 A B 59.918 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT C-A11 TCR homo sapiens homo sapiens homo sapiens | homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.214 0.167 True 4pjd F E NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 59.144 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-5-OP-RU in complex with human MAIT C-C10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.78 X-RAY DIFFRACTION 0.226 0.168 True 3sdx H G NA NA abTCR 0 C Hapten N-[(2S,3R)-1-(BETA-D-GALACTOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]TETRACOSANAMIDE GCY CD1 C D 27.474 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 10/05/11 Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Clarke, A.J., Patel, O., Rossjohn, J. 3.12 X-RAY DIFFRACTION 0.273 0.232 True 4jfd E D NA NA abTCR 0 C peptide melanoma peptide NA MH1 A B 42.674 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 05/29/13 Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K. 2.46 X-RAY DIFFRACTION 0.248 0.202 True 4pj5 H G NA NA abTCR 0 A Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 A B 58.867 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT TRBV6-1 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.220 0.180 True 2apt A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 2 X-RAY DIFFRACTION 0.210 0.175 True 6zky E D NA NA abTCR 0 C peptide enoyl-[acyl-carrier-protein] reductase [nadh] NA MH1 A B 59.775 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 01/26/22 Crystal structure of InhA:01 TCR in complex with HLA-E (S147C) bound to InhA (53-61 H3C) homo sapiens homo sapiens mycobacterium tuberculosis h37rv homo sapiens homo sapiens Srikannathasan, V., Karuppiah, V., Robinson, R.A. 2.65 X-RAY DIFFRACTION 0.273 0.227 True 5jhd J I NA NA abTCR 0 H peptide influenza m1(58-66) peptide NA MH1 F G 46.381 TRBV19 TRAV38 NA NA IMMUNE SYSTEM 03/01/17 Crystal structure of LS10-TCR/M1-HLA-A*02 complex homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Stern, L.J., Selin, L.K., Song, I. 2.46 X-RAY DIFFRACTION 0.223 0.204 True 6uln E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV4 NA NA IMMUNE SYSTEM 05/27/20 Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation homo sapiens homo sapiens Sun, P.D., Sim, M.J.W. 2.01 X-RAY DIFFRACTION 0.218 0.185 True 4p2q T S NA NA abTCR 0 R peptide 5c2 peptide NA MH2 P Q 30.995 TRBV26 TRAV4 NA NA IMMUNE SYSTEM 05/21/14 Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek mus musculus mus musculus synthetic construct mus musculus mus musculus Birnbaum, M.E., Ozkan, E., Garcia, K.C. 3.3 X-RAY DIFFRACTION 0.236 0.188 True 7n6e J I NA NA abTCR 0 C peptide spike protein s1 NA MH1 A B 53.210 TRBV19 TRAV12 NA NA IMMUNE SYSTEM/VIRAL PROTEIN 07/28/21 TCR peptide HLA-A2 complex homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Chaurasia, P., Rossjohn, J., Petersen, J. 3.2 X-RAY DIFFRACTION 0.294 0.239 True 4pj5 E D NA NA abTCR 0 C Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 C F 60.860 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/02/14 Structure of human MR1-Ac-6-FP in complex with human MAIT TRBV6-1 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2 X-RAY DIFFRACTION 0.220 0.180 True 3mbe D C NA NA abTCR 0 P peptide peptide hel 11-27 NA MH2 A B 46.828 TRBV13 TRAV4 NA NA IMMUNE SYSTEM 05/12/10 TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27) mus musculus mus musculus gallus gallus mus musculus mus musculus Corper, A.L., Yoshida, K., Teyton, L., Wilson, I.A. 2.886 X-RAY DIFFRACTION 0.281 0.253 True 7amq B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 04/20/22 Crystal structure of the complex of HuJovi-1 Fab with the human TRBC2 homo sapiens homo sapiens Ferrari, M., Bulek, A., Bughda, R., Jha, R., Welin, M., Logan, D.T., Sewell, A., Onuoha, S., Pule, M. 2.353 X-RAY DIFFRACTION 0.249 0.201 True 6tro E D NA NA abTCR 0 C peptide mage-a4 peptide (amino acids 230-239) NA MH1 A B 58.866 TRBV28 TRAV10 NA NA IMMUNE SYSTEM 06/24/20 Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., McMurran, C., Lloyd, A., Hibbert, L., Lupardus, P.J., Cole, D.K., Harper, S. 3 X-RAY DIFFRACTION 0.270 0.213 True 3scm D C NA NA abTCR 0 A Hapten N-[(2S,3R,4E)-1-{[ALPHA-D-GALACTOPYRANOSYL-(1->3)-BETA-D-GALACTOPYRANOSYL-(1->4)-BETA-D-GLUCOPYRANOSYL]OXY}-3-HYDROXYOCTADEC-4-EN-2-YL]HEXACOSANAMIDE LGN CD1 A B 24.474 TRBV19 TRAV11 NA NA IMMUNE SYSTEM 10/05/11 Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-isoglobotrihexosylceramide mus musculus , homo sapiens mus musculus , homo sapiens mus musculus mus musculus mus musculus Clarke, A.J., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.318 0.273 True 6vqo J H NA NA abTCR 0 Q peptide peptide from p53 tumor suppressor NA MH1 F G 28.583 TRBV27 TRAV12 NA NA IMMUNE SYSTEM 06/17/20 T cell receptor-p53-HLA-A2 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Gallagher, D.T., Pierce, B.G., Mariuzza, R.A. 3 X-RAY DIFFRACTION 0.211 0.162 True 3q5t A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV14 NA NA NA IMMUNE SYSTEM 03/16/11 V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures mus musculus Chen, Q., Zhang, H., Wang, J.-H. 2.005 X-RAY DIFFRACTION 0.290 0.235 True 7n2p F D NA NA abTCR 0 C peptide ribonuclease h2 subunit b NA MH1 A B 22.868 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 AS4.3-RNASEH2b-HLA*B27 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.5 X-RAY DIFFRACTION 0.288 0.230 True 1b88 NA A NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV14 NA NA IMMUNE SYSTEM 02/16/99 V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN mus musculus Plaksin, D., Chacko, S., Navaza, J., Margulies, D.H., Padlan, E.A. 2.5 X-RAY DIFFRACTION 0.324 0.224 True 8eo8 T S NA NA abTCR 0 R peptide nucleoprotein np8 epitope NA MH1 P Q 42.370 TRBV20 TRAV13 NA NA IMMUNE SYSTEM 03/27/24 Cross-reactive 3180 TCR recognition of HLA-B*35:01-NP8 epitope from 2005 H1N1 influenza strain homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Littler, D.R., Rossjohn, J. 2.3 X-RAY DIFFRACTION 0.219 0.181 True 7r80 B A NA NA abTCR 0 E peptide gln-ala-ser-gln-glu-val-lys-asn-trp NA MH1 C D 17.588 TRBV6 TRAV21 NA NA VIRAL PROTEIN/IMMUNE SYSTEM 06/29/22 Crystal structure of C3 TCR complex with QW9-bound HLA-B*5301 homo sapiens homo sapiens hiv-1 06tg.ht008 homo sapiens homo sapiens Li, X.L., Tan, K.M., Walker, B.D., Wang, J.H. 2.9 X-RAY DIFFRACTION 0.287 0.233 True 1h5b NA A NA NA NA 0 NA NA NA NA NA NA NA nan NA TRAV4 NA NA T CELL RECEPTOR 06/21/01 T cell receptor Valpha11 (AV11S5) domain mus musculus Machius, M., Cianga, P., Deisenhofer, J., Sally Ward, E. 1.85 X-RAY DIFFRACTION 0.245 0.224 True 4y4f H G NA NA abTCR 0 E Hapten (1R)-1,5-anhydro-1-[(1E,3S,4S,5R)-4,5-dihydroxy-3-(nonacosanoylamino)nonadec-1-en-1-yl]-D-galactitol 49M CD1 E F 27.942 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/GCK127/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Yu, E.D. 3.19 X-RAY DIFFRACTION 0.257 0.218 True 6rpb O N NA NA abTCR 0 M peptide heteroclitic ny-eso-1 157-165 peptide NA MH1 K L 69.408 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/15/20 Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Coles, C.H., Mulvaney, R., Malla, S., Lloyd, A., Smith, K., Chester, F., Knox, A., Stacey, A.R., Dukes, J., Baston, E., Griffin, S., Vuidepot, A., Jakobsen, B.K., Harper, S. 2.5 X-RAY DIFFRACTION 0.273 0.249 True 8i5c E D NA NA abTCR 0 C peptide tcr alpha chain NA MH1 A B 48.341 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 True 1bd2 E D NA NA abTCR 0 C peptide tax peptide NA MH1 A B 49.404 TRBV6 TRAV29 NA NA COMPLEX (MHC/VIRAL PEPTIDE/RECEPTOR) 08/19/98 COMPLEX BETWEEN HUMAN T-CELL RECEPTOR B7, VIRAL PEPTIDE (TAX) AND MHC CLASS I MOLECULE HLA-A 0201 homo sapiens homo sapiens human t-lymphotropic virus 1 homo sapiens homo sapiens Ding, Y.-H., Smith, K.J., Garboczi, D.N., Utz, U., Biddison, W.E., Wiley, D.C. 2.5 X-RAY DIFFRACTION 0.312 0.238 True 4l3e E D NA NA abTCR 0 C peptide melanoma antigen recognized by t-cells 1 NA MH1 A B 32.607 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 06/11/14 The complex between high affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Hellman, L.M. 2.557 X-RAY DIFFRACTION 0.266 0.229 True 4z7w H G NA NA abTCR 0 J | L | L peptide | carbohydrate | carbohydrate dq8-glia-alpha1 | ALPHA-D-MANNOSE | ALPHA-D-MANNOSE NA | MAN | MAN MH2 A B 45.518 TRBV6 TRAV8 NA NA IMMUNE SYSTEM 06/03/15 T316 complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Rossjohn, J., Reid, H.H., Koning, F. 2.89 X-RAY DIFFRACTION 0.247 0.228 True 7phr B A NA NA abTCR 0 P peptide tumor-associated antigentic peptide gp100 NA MH1 H L 43.774 TRBV19 TRAV17 NA NA IMMUNE SYSTEM 08/31/22 Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Susac, L., Thomas, C., Tampe, R. 3.08 ELECTRON MICROSCOPY NA NA True 3c60 F E NA NA abTCR 0 NA NA NA NA MH2 G H 47.036 TRBV13 TRAV6 NA NA SUGAR BINDING PROTEIN/IMMUNE SYSTEM 04/29/08 Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR YAe62 mus musculus mus musculus mus musculus mus musculus Dai, S. 3.05 X-RAY DIFFRACTION 0.309 0.267 True 4y4h D C NA NA abTCR 0 A Hapten (1R)-1,5-anhydro-1-{(1E,3S,4S,5R)-4,5-dihydroxy-3-[(8-phenyloctanoyl)amino]nonadec-1-en-1-yl}-D-galactitol 49X CD1 A B 28.154 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/GCK152/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Yu, E.D. 3.1 X-RAY DIFFRACTION 0.287 0.242 True 6pue H G NA NA abTCR 0 A Hapten 1,4-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol Q7J MR1 A B 61.237 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-4'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.232 0.199 True 4nhu D C NA NA abTCR 0 NA NA NA NA MH1 E NA 87.021 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 05/06/15 The M33 TCR p3M33l/H-2 Ld Complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus Birnbaum, M.E., Adams, J.J., Garcia, K.C. 2.9 X-RAY DIFFRACTION 0.260 0.229 True 4udt B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV7 TRAV22 NA NA IMMUNE SYSTEM 06/24/15 T cell receptor (TRAV22,TRBV7-9) structure homo sapiens homo sapiens Rodstrom, K.E.J., Regenthal, P., Lindkvist-Petersson, K. 1.35 X-RAY DIFFRACTION 0.193 0.156 True 6xqq D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV29 TRAV12 NA NA IMMUNE SYSTEM 08/19/20 Structure of human D462-E4 TCR homo sapiens homo sapiens Awad, W., Rossjohn, J. 2.68 X-RAY DIFFRACTION 0.223 0.194 True 6eh7 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 Human T-Cell Receptor specific for influenza virus haaemagglutinin epitope PKYVKQNTLKLAT carried by Human Leukocyte Antigen HLA-DR0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.89 X-RAY DIFFRACTION 0.232 0.185 True 3ffc J I NA NA abTCR 0 H peptide flrgraygl peptide from an ebv protein NA MH1 F G 29.779 TRBV11 TRAV14 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of CF34 TCR in complex with HLA-B8/FLR homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Gras, S., Burrows, S.R., Kjer-Nielsen, L., Clements, C.S., Liu, Y.C., Sullivan, L.C., Brooks, A.G., Purcell, A.W., McCluskey, J., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.268 0.221 True 1u3h B A NA NA abTCR 0 P peptide myelin basic protein (mbp)-peptide NA MH2 C D 41.853 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 05/17/05 Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A mus musculus mus musculus synthetic construct mus musculus mus musculus Maynard, J., Petersson, K., Wilson, D.H., Adams, E.J., Blondelle, S.E., Boulanger, M.J., Wilson, D.B., Garcia, K.C. 2.42 X-RAY DIFFRACTION 0.274 0.232 True 4pjf F E NA NA abTCR 0 C Hapten N-(6-FORMYL-4-OXO-3,4-DIHYDROPTERIDIN-2-YL)ACETAMIDE 30W MR1 C D 60.326 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 07/09/14 Structure of human MR1-Ac-6-FP in complex with human MAIT B-C10 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Birkinshaw, R.W., Rossjohn, J. 2.45 X-RAY DIFFRACTION 0.212 0.178 True 4jry E D NA NA abTCR 0 C peptide trans-activator protein bzlf1 NA MH1 A B 63.754 TRBV5 TRAV39 NA NA IMMUNE SYSTEM 04/10/13 Crystal Structure of SB47 TCR-HLA B*3505-LPEP complex homo sapiens homo sapiens human herpesvirus 4 homo sapiens homo sapiens Liu, Y.C., Rossjohn, J., Gras, S. 2.8 X-RAY DIFFRACTION 0.233 0.200 True 6fuq B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.6 X-RAY DIFFRACTION 0.211 0.173 True 4zdh B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV28 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 Crystal structure of JKA6 TCR homo sapiens homo sapiens Singh, N.K., Hossain, M., Baker, B.M. 2.0984 X-RAY DIFFRACTION 0.224 0.190 True 4iiq B A NA NA abTCR 0 C protein beta-2-microglobulin, mhc class i-related protein NA NA NA NA nan TRBV6 TRAV1 NA NA IMMUNE SYSTEM 04/24/13 Crystal structure of a human MAIT TCR in complex with bovine MR1 homo sapiens homo sapiens bos taurus Lopez-Sagaseta, J., Adams, E.J. 2.86 X-RAY DIFFRACTION 0.271 0.213 True 5u72 G B NA NA abTCR 0 NA NA NA NA MR1 A H 61.797 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/08/17 Structure of human MR1-5OH-DCF in complex with human MAIT A-F7 TCR homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Rossjohn, J. 2.5 X-RAY DIFFRACTION 0.231 0.173 True 1tcr B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV13 TRAV9 NA NA RECEPTOR 03/12/97 MURINE T-CELL ANTIGEN RECEPTOR 2C CLONE mus musculus mus musculus Garcia, K.C., Degano, M., Stanfield, R.L., Wilson, I.A. 2.5 X-RAY DIFFRACTION 0.285 0.208 True 7su9 E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV4 NA NA IMMUNE SYSTEM 06/08/22 KRAS-G12D specific TCR9a in complex with C*05-GADGVGKSL homo sapiens homo sapiens Sim, M.J.W., Sun, P.D. 1.99 X-RAY DIFFRACTION 0.214 0.181 True 5wkf E D NA NA abTCR 0 C peptide gts1 peptide NA MH1 A B 39.587 TRBV11 TRAV30 NA NA IMMUNE SYSTEM 09/20/17 D30 TCR in complex with HLA-A*11:01-GTS1 homo sapiens homo sapiens dengue virus 1 homo sapiens homo sapiens Gras, S., Rossjohn, J. 2.95 X-RAY DIFFRACTION 0.253 0.190 True 5sws E D NA NA abTCR 0 C peptide influenza np366 epitope NA MH1 A B 52.062 TRBV17 TRAV14 NA NA IMMUNE SYSTEM 10/05/16 Crystal Structure of NP2-B17 TCR-H2Db-NP complex mus musculus mus musculus unidentified influenza virus mus musculus mus musculus Gras, S., Del Campo, C.M., Farenc, C., Josephs, T.M., Rossjohn, J. 2.86 X-RAY DIFFRACTION 0.274 0.231 True 8trr E D NA NA abTCR 0 C peptide vimentin NA MH2 A B 37.855 TRBV13 TRAV6 NA NA IMMUNE SYSTEM 07/31/24 T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 mus musculus mus musculus homo sapiens homo sapiens homo sapiens Loh, T.J., Lim, J.J., Reid, H.H., Rossjohn, J. 2.65 X-RAY DIFFRACTION 0.244 0.209 True 7k0x NA NA NA B NA 0 A | A protein | carbohydrate t cell receptor mu chain | N-ACETYL-D-GLUCOSAMINE NA | NAG NA NA NA nan NA NA NA NA IMMUNE SYSTEM 03/24/21 Marsupial T cell receptor Spl_145 monodelphis domestica monodelphis domestica | monodelphis domestica Wegrecki, M., Kannan Sivaraman, K., Le Nours, J., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.251 0.203 True 3ffc E D NA NA abTCR 0 C peptide flrgraygl peptide from an ebv protein NA MH1 A B 28.329 TRBV11 TRAV14 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of CF34 TCR in complex with HLA-B8/FLR homo sapiens homo sapiens synthetic construct homo sapiens homo sapiens Gras, S., Burrows, S.R., Kjer-Nielsen, L., Clements, C.S., Liu, Y.C., Sullivan, L.C., Brooks, A.G., Purcell, A.W., McCluskey, J., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.268 0.221 True 1jck A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA COMPLEX (TOXIN/RECEPTOR) 11/12/97 T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SEC3 SUPERANTIGEN mus musculus Fields, B.A., Mariuzza, R.A. 3.5 X-RAY DIFFRACTION 0.328 0.238 True 6uz1 E D NA NA abTCR 0 C peptide leu-leu-phe-gly-tyr-pro-val-tyr-val NA MH1 A B 59.964 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 10/28/20 Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with Tax/HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Ma, J., Singh, N.K. 3.14 X-RAY DIFFRACTION 0.239 0.189 True 4wnq B NA NA NA NA 0 A protein tcr variable delta 1 chain and tcr constant alpha chain NA NA NA NA nan TRBV20 NA NA NA IMMUNE SYSTEM 11/26/14 THE MOLECULAR BASES OF DELTA/ALPHA-BETA T-CELL MEDIATED ANTIGEN RECOGNITION homo sapiens homo sapiens Pellicci, D.G., Uldrich, A.P., Le Nours, J., Ross, F., Chabrol, E., Eckle, S.B.G., de Boer, R., Lim, R.T., McPherson, K., Besra, G., Howell, A.R., Moretta, L., McCluskey, J., Heemskerk, M.H.M., Gras, S., Rossjohn, J., Godfrey, D.I. 1.8 X-RAY DIFFRACTION 0.229 0.193 True 1fo0 B A NA NA abTCR 0 P peptide naturally processed octapeptide pbm1 NA MH1 H L 41.362 TRBV1 TRAV16 NA NA IMMUNE SYSTEM 10/02/00 MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX mus musculus mus musculus mus musculus mus musculus Reiser, J.B., Darnault, C., Guimezanes, A., Gregoire, C., Mosser, T., Schmitt-Verhulst, A.-M., Fontecilla-Camps, J.C., Malissen, B., Housset, D., Mazza, G. 2.5 X-RAY DIFFRACTION 0.276 0.225 True 7jwi E D NA NA abTCR 0 C peptide nucleoprotein NA MH1 A B 52.780 TRBV17 TRAV14 NA NA IMMUNE SYSTEM 07/07/21 Crystal structure of B17.R2 TCR in complex with H2D-b-NP366 mus musculus mus musculus influenza a virus mus musculus homo sapiens Farenc, C., Rossjohn, J. 3.02 X-RAY DIFFRACTION 0.281 0.239 True 8d5q B A NA NA abTCR 0 E peptide dense granule protein 6, hf10 peptide NA MH1 C NA 31.670 TRBV1 TRAV6 NA NA IMMUNE SYSTEM 09/14/22 TCR TG6 in complex with Ld-HF10 mus musculus mus musculus toxoplasma gondii mus musculus Wang, Y., Dai, S. 2.501 X-RAY DIFFRACTION 0.222 0.169 True 3e3q a Z NA NA abTCR 0 b peptide unknown NA MH1 Y NA 42.203 TRBV13 TRAV9 NA NA IMMUNE SYSTEM 11/04/08 Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9 mus musculus mus musculus mus musculus Colf, L.A., Garcia, K.C. 2.95 X-RAY DIFFRACTION 0.275 0.250 True 5d2l L K NA NA abTCR 0 U peptide asn-leu-val-pro-met-val-ala-thr-val NA MH1 G H 29.333 TRBV7 TRAV24 NA NA IMMUNE SYSTEM 10/07/15 Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2 homo sapiens homo sapiens cytomegalovirus homo sapiens homo sapiens Gao, M., Mariuzza, R.A. 3.511 X-RAY DIFFRACTION 0.355 0.270 True 6eh5 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV21 NA NA IMMUNE SYSTEM 04/18/18 003 Human T-Cell Receptor specific for HIV GAG epitope SLYNTVATL carried by Human Leukocyte Antigen HLA-A*0201 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.29 X-RAY DIFFRACTION 0.195 0.168 True 6bnk H G NA NA abTCR 0 E carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 E F 25.909 NA NA NA NA IMMUNE SYSTEM 04/04/18 Crystal structure of TCR-MHC-like molecule homo sapiens homo sapiens mus musculus mus musculus mus musculus Le Nours, J., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.220 0.201 True 6vrm E D NA NA abTCR 0 P peptide cellular tumor antigen p53 peptide NA MH1 A B 51.427 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 06/17/20 T cell receptor-p53-HLA-A2 complex homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Gallagher, D.T., Gowthaman, R., Pierce, B.G., Mariuzza, R.A. 2.61 X-RAY DIFFRACTION 0.275 0.191 True 6cw6 D C NA NA abTCR 0 A Hapten (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL PBS CD1 A B 25.826 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 04/03/19 Structure of alpha-GC[8,18] bound by CD1d and in complex with the Va14Vb8.2 TCR mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Wang, J., Zajonc, D. 2.85 X-RAY DIFFRACTION 0.250 0.209 True 7n2r F D NA NA abTCR 0 C peptide pre-mrna processing factor 3 NA MH1 A B 22.100 TRBV9 TRAV21 NA NA IMMUNE SYSTEM 12/07/22 AS4.3-PRPF3-HLA*B27 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Yang, X., Jude, K.M., Garcia, K.C. 2.28 X-RAY DIFFRACTION 0.288 0.248 True 3qh3 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/04/12 The crystal structure of TCR A6 homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.19 X-RAY DIFFRACTION 0.274 0.202 True 2axh B NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV19 NA NA NA IMMUNE SYSTEM 09/20/05 Crystal structures of T cell receptor beta chains related to rheumatoid arthritis homo sapiens Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y. 2.7 X-RAY DIFFRACTION 0.280 0.237 True 6pud H G NA NA abTCR 0 A Hapten 6-[(5-hydroxypentyl)amino]-5-[(E)-propylideneamino]pyrimidine-2,4(1H,3H)-dione OYD MR1 A B 61.769 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-5'OH-Pentyl-5-OP-U homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.8 X-RAY DIFFRACTION 0.200 0.164 True 3tyf D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 04/25/12 Crystal structure of a CD1d-lysophosphatidylcholine reactive iNKT TCR escherichia coli escherichia coli Lopez-Sagaseta, J., Adams, E.J. 2.806 X-RAY DIFFRACTION 0.272 0.217 True 1fyt E D NA NA abTCR 0 C peptide hemagglutinin ha1 peptide chain NA MH2 A B 46.624 TRBV28 TRAV8 NA NA IMMUNE SYSTEM 11/08/00 CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1 homo sapiens homo sapiens h3n2 subtype homo sapiens homo sapiens Hennecke, J., Carfi, A., Wiley, D.C. 2.6 X-RAY DIFFRACTION 0.255 0.221 True 3qfj E D NA NA abTCR 0 C peptide tax(y5f) peptide NA MH1 A B 35.624 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 01/11/12 The complex between TCR A6 and human Class I MHC HLA-A2 with the modified TAX (Y5F) peptide homo sapiens homo sapiens homo sapiens homo sapiens Borbulevych, O.Y., Baker, B.M. 2.29 X-RAY DIFFRACTION 0.271 0.218 True 2j8u F E NA NA abTCR 0 C peptide self-peptide p1049 NA MH1 A B 68.877 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 10/16/07 Large CDR3a loop alteration as a function of MHC mutation. mus musculus mus musculus homo sapiens homo sapiens homo sapiens Miller, P.J., Benhar, Y.P., Biddison, W., Collins, E.J. 2.88 X-RAY DIFFRACTION 0.293 0.268 True 7rm4 S T NA NA abTCR 0 R peptide cellular tumor antigen p53 peptide NA MH1 P Q 35.179 TRBV11 TRAV6 NA NA IMMUNE SYSTEM 02/09/22 Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Wu, D., Mariuzza, R.A. 3.33 X-RAY DIFFRACTION 0.295 0.237 True 4y2d D C NA NA abTCR 0 A Hapten 11-(4-fluorophenyl)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]undecanamide 7DW CD1 A B 26.842 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/7DW8-5/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Yu, E.D. 3.05 X-RAY DIFFRACTION 0.257 0.217 True 2nts P NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV5 NA NA NA TOXIN/IMMUNE SYSTEM 06/26/07 Crystal Structure of SEK-hVb5.1 homo sapiens Gunther, S., Varma, A.K., Moza, B., Sundberg, E.J. 2.4 X-RAY DIFFRACTION 0.240 0.219 True 3r8b N NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 6lir D C NA NA abTCR 0 NA NA NA NA NA NA NA nan NA NA NA NA IMMUNE SYSTEM 11/18/20 crystal structure of chicken TCR for 2.0 gallus gallus gallus gallus Zhang, L., Xia, C. 2.091 X-RAY DIFFRACTION 0.236 0.205 True 2eys B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV25 TRAV10 NA NA IMMUNE SYSTEM 03/21/06 A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition homo sapiens homo sapiens Kjer-Nielsen, L., Borg, N.A. 2.21 X-RAY DIFFRACTION 0.278 0.211 True 4irj D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-({6-O-[(4-chlorophenyl)carbamoyl]-alpha-D-galactopyranosyl}oxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanamide 1L9 CD1 A B 25.092 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 08/28/13 Structure of the mouse CD1d-4ClPhC-alpha-GalCer-iNKT TCR complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Nemcovic, M., Zajonc, D.M. 3 X-RAY DIFFRACTION 0.228 0.186 True 3huj F E NA NA abTCR 0 C carbohydrate N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE AGH CD1 C D 29.888 TRBV25 TRAV10 NA NA IMMUNE SYSTEM 07/28/09 Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell receptor homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Pang, S.S. 2.5 X-RAY DIFFRACTION 0.279 0.216 True 3gsn B A NA NA abTCR 0 P peptide hcmv pp65 fragment 495-503 (nlvpmvatv) NA MH1 H L 39.456 TRBV6 TRAV24 NA NA IMMUNE SYSTEM 08/04/09 Crystal structure of the public RA14 TCR in complex with the HCMV dominant NLV/HLA-A2 epitope homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Saulquin, X., Reiser, J.-B., Debeaupuis, E., Echasserieau, K., Kissenpfennig, A., Legoux, F., Chouquet, A., Le Gorrec, M., Machillot, P., Neveu, B., Thielens, N., Malissen, B., Bonneville, M., Housset, D. 2.8 X-RAY DIFFRACTION 0.290 0.215 True 3rzc D C NA NA abTCR 0 A Hapten N-[(2S,3R,4E)-1-{[ALPHA-D-GALACTOPYRANOSYL-(1->3)-BETA-D-GALACTOPYRANOSYL-(1->4)-BETA-D-GLUCOPYRANOSYL]OXY}-3-HYDROXYOCTADEC-4-EN-2-YL]HEXACOSANAMIDE LGN CD1 A B 25.309 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 08/24/11 Structure of the self-antigen iGb3 bound to mouse CD1d and in complex with the iNKT TCR mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Yu, E.D., Girardi, E., Wang, J., Zajonc, D.M. 2.8 X-RAY DIFFRACTION 0.271 0.236 True 6ovo B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV4 TRAV13 NA NA IMMUNE SYSTEM 11/20/19 Crystal structure of the unliganded PG10 TCR homo sapiens homo sapiens Shahine, A., Rossjohn, J. 2.49 X-RAY DIFFRACTION 0.222 0.177 True 2ian E D NA NA abTCR 0 C peptide 15-mer peptide from triosephosphate isomerase NA MH2 A B 42.980 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.296 0.221 True 5c0c J I NA NA abTCR 0 C peptide marker peptide NA MH1 A B 43.810 TRBV12 TRAV12 NA NA IMMUNE SYSTEM 05/04/16 1E6 TCR in complex with HLA-A02 carrying RQFGPDWIVA homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K. 1.974 X-RAY DIFFRACTION 0.227 0.189 True 2uwe M L NA NA abTCR 0 J peptide uncharacterized protein c15orf24 NA MH1 H I 65.155 TRBV13 TRAV12 NA NA IMMUNE SYSTEM 09/25/07 Large CDR3a loop alteration as a function of MHC mutation mus musculus mus musculus homo sapiens homo sapiens homo sapiens Miller, P.J., Pazy, Y., Conti, B., Riddle, D., Biddison, W.E., Appella, E., Collins, E.J. 2.4 X-RAY DIFFRACTION 0.290 0.240 True 2ian T S NA NA abTCR 0 R peptide 15-mer peptide from triosephosphate isomerase NA MH2 P Q 43.306 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 04/03/07 Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Deng, L., Langley, R.J., Mariuzza, R.A. 2.8 X-RAY DIFFRACTION 0.296 0.221 True 1bec A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA RECEPTOR 10/25/95 BETA CHAIN OF A T CELL ANTIGEN RECEPTOR mus musculus Bentley, G.A., Boulot, G., Karjalainen, K., Mariuzza, R.A. 1.7 X-RAY DIFFRACTION unknown 0.198 True 6dfx J I NA NA abTCR 0 NA NA NA NA MH2 D E 34.100 TRBV5 TRAV17 NA NA IMMUNE SYSTEM 04/17/19 human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide homo sapiens homo sapiens homo sapiens homo sapiens Wang, Y., Dai, S. 2.03 X-RAY DIFFRACTION 0.217 0.181 True 3r8b F NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA TOXIN/IMMUNE SYSTEM 04/06/11 Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8 rattus norvegicus Bonsor, D.A., Sundberg, E.J. 2.95 X-RAY DIFFRACTION 0.265 0.246 True 5e9d E D NA NA abTCR 0 C peptide melanoma derived mart-1 peptide NA MH1 A B 41.282 TRBV6 TRAV12 NA NA PROTEIN BINDING 06/08/16 RD-1 Mart-1 High bound to Mart-1 decameric peptide (ELA) in complex with HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Singh, N.K., Baker, B.M. 2.51 X-RAY DIFFRACTION 0.232 0.180 True 4lcw E D NA NA abTCR 0 C Hapten 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol 1VY MR1 C F 62.406 TRBV6 TRAV1 NA NA Membrane Protein/Immune System 10/02/13 The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Patel, O., Rossjohn, J. 2.4 X-RAY DIFFRACTION 0.227 0.179 True 6v13 E D NA NA abTCR 0 C peptide fibrinogen beta 74cit69-81 NA MH2 A B 25.371 TRBV4 TRAV6 NA NA IMMUNE SYSTEM 11/25/20 immune receptor complex mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lim, J.J., Rossjohn, J. 2.75 X-RAY DIFFRACTION 0.247 0.210 True 6uz1 J I NA NA abTCR 0 H peptide leu-leu-phe-gly-tyr-pro-val-tyr-val NA MH1 F G 57.228 TRBV6 TRAV12 NA NA IMMUNE SYSTEM 10/28/20 Noncanonical binding of single-chain A6 TCR variant S3-4 in complex with Tax/HLA-A2 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Ma, J., Singh, N.K. 3.14 X-RAY DIFFRACTION 0.239 0.189 True 3c6l B A NA NA abTCR 0 NA NA NA NA MH2 C D 40.944 TRBV13 TRAV14 NA NA SUGAR BINDING PROTEIN/IMMUNE SYSTEM 04/29/08 Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20 mus musculus mus musculus mus musculus mus musculus Dai, S. 3.4 X-RAY DIFFRACTION 0.325 0.268 True 7ow6 E D NA NA abTCR 0 C peptide kras g12d peptide (vvvgadgvgk) NA MH1 A B 48.664 TRBV6 TRAV19 NA NA IMMUNE SYSTEM 07/20/22 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK) homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Robinson, R.A. 2.64 X-RAY DIFFRACTION 0.268 0.211 True 6cqq J I NA NA abTCR 0 H peptide peptide from capsid protein p24 NA MH2 F G 34.516 TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of F24 TCR -DR15-RQ13 peptide complex homo sapiens homo sapiens hiv-1 m homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 2.8 X-RAY DIFFRACTION 0.254 0.207 True 5euo F E NA NA abTCR 0 J peptide matrix protein 1 NA MH1 A B 65.213 TRBV19 TRAV27 NA NA IMMUNE SYSTEM 11/23/16 PF6-M1-HLA-A2 homo sapiens homo sapiens influenza a virus homo sapiens homo sapiens Yang, X. 2.1 X-RAY DIFFRACTION 0.281 0.229 True 6puk E D NA NA abTCR 0 C Hapten 1,2-dideoxy-1-{2,6-dioxo-5-[(1E)-3-oxobut-1-en-1-yl]-1,2,3,6-tetrahydropyrimidin-4-yl}-D-ribo-hexitol OYV MR1 C F 57.965 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-JYM72 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 2.08 X-RAY DIFFRACTION 0.202 0.176 True 8vd0 J I NA NA abTCR 0 NA NA NA NA MH2 F H 39.101 TRBV5 TRAV26 NA NA IMMUNE SYSTEM 08/07/24 Human TCR ET650-4 in complex with DQ8-InsC8-15-IAPP2 homo sapiens homo sapiens homo sapiens homo sapiens Tran, T.M., Lim, J.J., Loh, T.Y., Mannering, I.S., Rossjohn, J., Reid, H.H. 2.4 X-RAY DIFFRACTION 0.220 0.188 True 4ozf H G NA NA abTCR 0 J peptide deamidated gliadin-alpha2 peptide NA MH2 A B 45.953 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/16/14 JR5.1 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 2.7 X-RAY DIFFRACTION 0.238 0.184 True 4y2d H G NA NA abTCR 0 E Hapten 11-(4-fluorophenyl)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]undecanamide 7DW CD1 E F 25.203 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 05/27/15 Crystal structure of the mCD1d/7DW8-5/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Yu, E.D. 3.05 X-RAY DIFFRACTION 0.257 0.217 True 5nme E D NA NA abTCR 0 C peptide gag protein NA MH1 A B 52.384 TRBV5 TRAV12 NA NA IMMUNE SYSTEM 11/15/17 868 TCR in complex with HLA A02 presenting SLYNTVATL homo sapiens homo sapiens human immunodeficiency virus 1 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K. 2.94 X-RAY DIFFRACTION 0.263 0.196 True 4jfe E D NA NA abTCR 0 C peptide melanoma peptide l7a NA MH1 A B 42.798 TRBV30 TRAV12 NA NA IMMUNE SYSTEM 05/29/13 Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K. 2.7 X-RAY DIFFRACTION 0.250 0.202 True 8i5c Y X NA NA abTCR 0 W peptide tcr alpha chain NA MH1 U V 47.773 TRBV13 TRAV7 NA NA IMMUNE SYSTEM 08/23/23 Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) mus musculus mus musculus homo sapiens homo sapiens homo sapiens Lu, D., Chen, Y., Jiang, M., Tan, S.G., Chai, Y., Gao, G.F. 3.34 X-RAY DIFFRACTION 0.258 0.224 True 6pue E D NA NA abTCR 0 C Hapten 1,4-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol Q7J MR1 C F 59.809 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-4'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Rossjohn, J. 1.9 X-RAY DIFFRACTION 0.232 0.199 True 2apb A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the S54N variant of murine T cell receptor Vbeta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 1.8 X-RAY DIFFRACTION 0.258 0.187 True 7zt5 E D NA NA abTCR 0 NA NA NA NA MR1 A B 59.883 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex in human MR1 bound to 3FSA homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Robinson, R.A. 2.09 X-RAY DIFFRACTION 0.266 0.225 True 3mv9 E D NA NA abTCR 0 C peptide hpvg peptide from epstein-barr nuclear antigen 1 NA MH1 A B 41.382 TRBV9 TRAV20 NA NA IMMUNE SYSTEM 06/09/10 Crystal Structure of the TK3-Gln55Ala TCR in complex with HLA-B*3501/HPVG homo sapiens homo sapiens homo sapiens homo sapiens Gras, S., Chen, Z., Miles, J.J., Liu, Y.C., Bell, M.J., Sullivan, L.C., Kjer-Nielsen, L., Brennan, R.M., Burrows, J.M., Neller, M.A., Khanna, R., Purcell, A.W., Brooks, A.G., McCluskey, J., Rossjohn, J., Burrows, S.R. 2.7 X-RAY DIFFRACTION 0.331 0.234 True 6cph E D NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV2 TRAV24 NA NA IMMUNE SYSTEM 06/06/18 Crystal structure of the F24 TCR homo sapiens homo sapiens Farenc, C., Gras, S., Rossjohn, J. 1.7 X-RAY DIFFRACTION 0.233 0.204 True 6frc B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.59 X-RAY DIFFRACTION 0.198 0.174 True 6q3s E D NA NA abTCR 0 C peptide ser-leu-leu-met-trp-ile-thr-gln-val NA MH1 A B 67.059 TRBV6 TRAV21 NA NA IMMUNE SYSTEM 07/24/19 Engineered Human HLA_A2 MHC Class I molecule in complex with TCR and SV9 peptide homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Meijers, R., Anjanappa, R., Springer, S., Garcia-Alai, M. 2.5 X-RAY DIFFRACTION 0.273 0.229 True 6puk G B NA NA abTCR 0 A Hapten 1,2-dideoxy-1-{2,6-dioxo-5-[(1E)-3-oxobut-1-en-1-yl]-1,2,3,6-tetrahydropyrimidin-4-yl}-D-ribo-hexitol OYV MR1 A H 61.134 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1-JYM72 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 2.08 X-RAY DIFFRACTION 0.202 0.176 True 7zt3 E D NA NA abTCR 0 NA NA NA NA MR1 A B 58.832 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex in human MR1 K43A homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Srikannathasan, V., Robinson, R.A. 2.4 X-RAY DIFFRACTION 0.236 0.191 True 1ktk F NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV20 NA NA NA IMMUNE SYSTEM 06/07/02 Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1) homo sapiens Sundberg, E.J., Li, H., Llera, A.S., McCormick, J.K., Tormo, J., Karjalainen, K., Schlievert, P.M., Mariuzza, R.A. 3 X-RAY DIFFRACTION 0.334 0.326 True 6dfq D C NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV1 TRAV10 NA NA IMMUNE SYSTEM 04/17/19 mouse diabetogenic TCR I.29 mus musculus mus musculus Wang, Y., Dai, S. 2.6 X-RAY DIFFRACTION 0.253 0.220 True 5d5m F E NA NA abTCR 0 C Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 C D 61.242 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 01/27/16 Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Keller, A.N., Birkinshaw, R.W., Rossjohn, J. 2.2 X-RAY DIFFRACTION 0.222 0.171 True 6fr5 B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV5 TRAV21 NA NA IMMUNE SYSTEM 04/18/18 HA1.7 TCR Study of CDR Loop Flexibility homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.37 X-RAY DIFFRACTION 0.191 0.168 True 5men E D NA NA abTCR 0 C peptide ile-leu-ala-lys-phe-leu-his-trp-leu NA MH1 A B 40.823 TRBV6 TRAV22 NA NA IMMUNE SYSTEM 12/07/16 Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K. 2.81 X-RAY DIFFRACTION 0.272 0.189 True 1ao7 E D NA NA abTCR 0 C peptide tax peptide NA MH1 A B 34.827 TRBV6 TRAV12 NA NA COMPLEX (MHC/VIRAL PEPTIDE/RECEPTOR) 09/17/97 COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201 homo sapiens homo sapiens human t-lymphotropic virus 1 homo sapiens homo sapiens Garboczi, D.N., Ghosh, P., Utz, U., Fan, Q.R., Biddison, W.E., Wiley, D.C. 2.6 X-RAY DIFFRACTION 0.320 0.245 True 6fup B A NA NA abTCR 0 NA NA NA NA NA NA NA nan TRBV24 TRAV8 NA NA IMMUNE SYSTEM 04/18/18 F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 homo sapiens homo sapiens Rizkallah, P.J., Cole, D.K. 1.72 X-RAY DIFFRACTION 0.215 0.176 True 8dnt I H NA NA abTCR 0 J peptide nucleoprotein NA MH1 K L 34.664 NA NA NA NA IMMUNE SYSTEM 01/08/09 SARS-CoV-2 specific T cell receptor homo sapiens homo sapiens severe acute respiratory syndrome coronavirus2 homo sapiens homo sapiens Gallagher, D.T., Wu, D., Gowthaman, R., Pierce, B.G., Mariuzza, R.A., Weng, N.P. 3.18 X-RAY DIFFRACTION 0.313 0.221 True 6pul G B NA NA abTCR 0 A Hapten 1,3-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol Q81 MR1 A H 60.562 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 02/19/20 Structure of human MAIT A-F7 TCR in complex with human MR1 3'D-5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Awad, W., Keller, A.N., Rossjohn, J. 1.84 X-RAY DIFFRACTION 0.184 0.156 True 4ozg F E NA NA abTCR 0 I peptide deamidated gliadin-alpha2 peptide NA MH2 C D 34.160 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 04/16/14 D2 protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Petersen, J., Reid, H.H., Rossjohn, J. 3 X-RAY DIFFRACTION 0.241 0.203 True 7sg2 E D NA NA abTCR 0 C peptide dq2-glia-omega1 peptide NA MH2 A B 36.806 TRBV29 TRAV4 NA NA IMMUNE SYSTEM 02/23/22 XPA5 TCR in complex with HLA-DQ2-omega1 homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Ciacchi, L., Farenc, C., Petersen, J., Reid, H.H., Rossjohn, J. 3.1 X-RAY DIFFRACTION 0.259 0.218 True 7zt2 E D NA NA abTCR 0 A Hapten 1-DEOXY-1-({2,6-DIOXO-5-[(E)-(2-OXOPROPYLIDENE)AMINO]-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL}AMINO)-D-RIBITOL 2LJ MR1 A B 59.058 TRBV6 TRAV1 NA NA IMMUNE SYSTEM 06/28/23 Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU homo sapiens homo sapiens homo sapiens homo sapiens homo sapiens Karuppiah, V., Srikannathasan, V., Robinson, R.A. 2.4 X-RAY DIFFRACTION 0.276 0.215 True 6miv D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-1-({4-O-[(4-tert-butylphenyl)methyl]-alpha-D-galactopyranosyl}oxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanamide JU1 CD1 A B 25.598 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 01/09/19 Crystal structure of the mCD1d/xxq (JJ300)/iNKTCR ternary complex mus musculus, homo sapiens mus musculus, homo sapiens mus musculus mus musculus mus musculus Zajonc, D.M., Bitra, A., Janssens, J. 2.05 X-RAY DIFFRACTION 0.219 0.185 True 3rtq D C NA NA abTCR 0 A Hapten N-[(2S,3S,4R)-3,4-DIHYDROXY-1-{[(1S,2S,3R,4R,5S)-2,3,4,5-TETRAHYDROXYCYCLOHEXYL]AMINO}OCTADECAN-2-YL]HEXACOSANAMIDE H4S CD1 A B 26.518 TRBV13 TRAV11 NA NA IMMUNE SYSTEM 02/22/12 Structure of the mouse CD1d-HS44-iNKT TCR complex mus musculus mus musculus mus musculus mus musculus mus musculus Yu, E.D., Zajonc, D.M. 2.8 X-RAY DIFFRACTION 0.268 0.227 True 3dxa O N NA NA abTCR 0 M peptide ebv decapeptide epitope NA MH1 K L 58.225 TRBV7 TRAV26 NA NA IMMUNE SYSTEM 01/27/09 Crystal Structure of the DM1 TCR in complex with HLA-B*4405 and decamer EBV antigen homo sapiens homo sapiens homo sapiens homo sapiens Archbold, J.K., Macdonald, W.A., Gras, S., Rossjohn, J. 3.5 X-RAY DIFFRACTION 0.330 0.286 True 1d9k B A NA NA abTCR 0 P peptide conalbumin peptide NA MH2 C D 51.570 TRBV13 TRAV14 NA NA IMMUNE SYSTEM 12/15/99 CRYSTAL STRUCTURE OF COMPLEX BETWEEN D10 TCR AND PMHC I-AK/CA mus musculus mus musculus mus musculus mus musculus mus musculus Reinherz, E.L., Tan, K., Tang, L., Kern, P., Liu, J.-H., Xiong, Y., Hussey, R.E., Smolyar, A., Hare, B., Zhang, R., Joachimiak, A., Chang, H.-C., Wagner, G., Wang, J.-H. 3.2 X-RAY DIFFRACTION 0.293 0.247 True 4gg6 H G NA NA abTCR 0 J peptide peptide from alpha/beta-gliadin mm1 NA MH2 A B 39.301 TRBV9 TRAV26 NA NA IMMUNE SYSTEM 10/24/12 Protein complex homo sapiens homo sapiens triticum aestivum homo sapiens homo sapiens Broughton, S.E., Theodossis, A., Petersen, J., Reid, H.H., Rossjohn, J. 3.2 X-RAY DIFFRACTION 0.285 0.246 True 2apf A NA NA NA NA 0 NA NA NA NA NA NA NA nan TRBV13 NA NA NA IMMUNE SYSTEM 03/21/06 Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain rattus norvegicus Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J. 1.8 X-RAY DIFFRACTION 0.263 0.197 True