Coronavirus-Binding Antibody Sequences & Structures

The Oxford Protein Informatics Group (Dept. of Statistics, University of Oxford) is collaborating in efforts to understand the immune response to SARS-CoV2 infection and vaccination. As part of our investigations, we are releasing and maintaining this public database to document all published/patented binding antibodies and nanobodies to coronaviruses, including SARS-CoV2, SARS-CoV1, and MERS-CoV.

Explanations and a preliminary analysis of the database contents can be found in our Applications Note in Bioinformatics. Please consider citing it if you are making use of our database in your research. BibTex Reference.

If you have recently released a preprint, paper, or publication with SARS-CoV-2 binding antibodies, please let us know by emailing opig [at] stats.ox.ac.uk.

CoV-AbDab currently contains 3,290 entries (last updated: 24th July 2021).

>   Search Database by Attribute

To view all entries, leave all search fields as 'All' and click 'Search'.

Type:
Binds to:
Doesn't bind to:
Neutralising against:
Not neutralising against:
Protein/Epitope:
Origin:
Heavy V Gene:
Heavy J Gene:
Light V Gene:
Light J Gene:
Added since:
Updated since:
>   Search Database by Sequence

Enter a sequence (either a full-length variable domain sequence or a CDR3 sequence) and click Submit to search our database for similar sequences to your query.

Only database entries that are the same length as your query are considered.

Query sequence:

Matthew I. J. Raybould, Aleksandr Kovaltsuk, Claire Marks, Charlotte M. Deane (2021) CoV-AbDab: the Coronavirus Antibody Database. Bioinformatics. 37(5):734-735. doi = 10.1093/bioinformatics/btaa739.

Download BibTex Reference

Header image credit: David Goodsell