The Structural Antibody Database

Welcome to SAbDab

SAbDab is a database containing all the antibody structures available in the PDB, annotated and presented in a consistent fashion.

Each structure is annotated with a number of properties including experimental details, antibody nomenclature (e.g. heavy-light pairings), curated affinity data and sequence annotations. You can use the database to inspect individual structures, create and download datasets for analysis, search the database for structures with similar sequences to your query, monitor the known structural repetoire of antibodies, and much more. All nanobody structures in the PDB can also be found in SAbDab.

SAbDab was built by the Oxford Protein Informatics Group (OPIG) under an open-innovation agreement.

Our antibody prediction tools (such as modelling software, developability prediction software etc.) can be found at our SAbPred site.

Database Statistics

See a summary of the data contained within SAbDab

Search Structures

Search for and view the antibody structures contained in the database.

Search CDRs

Explore the complementarity determining regions (CDRs) of the antibodies in SAbDab.

Search by Sequence

Search for structures based on sequence identity.

Search by Orientation

Select antibodies based on the relative orientation of their VH and VL using ABangle.

Thera-SAbDab

Our database of Antibody- and Nanobody-derived Immunotherapeutic Structures: search by INN, metadata, or sequence.

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]