Structure Viewer: 3cxh

>   Structure details

Structure of Yeast complex Iii with isoform-2 Cytochrome C Bound and Definition of a Minimal Core interface For Electron Transfer.

PDB3cxh
SpeciesMUS MUSCULUS
MethodX-RAY DIFFRACTION
Resolution2.5Å
Number of Fvs2
In complexTrue
Light chain typeKappa
Has constant regionFalse
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>   Fv information

This PDB has 2 Fv(s).

>   U/V
Fv Details
Heavy chainU
Light chainV
Heavy subgroupIGHV3
Light subgroupIGKV10
SpeciesMUS MUSCULUS
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 101 102 103 104 105 106 107 108 109 110 111 112 113
E V K L Q E S G A G L V Q P S Q S L S L T C S V T G Y S I T S G Y Y W N W I R L F P G N K L E W V G Y I S N V G D N N Y N P S L K D R L S I T R D T S K N Q F F L K L N S V T T E D T A T Y Y C A R S E Y Y S V T G Y A M D Y W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I E L T Q T P V S L A A S L G D R V T I S C R A S Q D I N N F L N W Y Q Q K P D G T I K L L I Y Y T S R L H A G V P S R F S G S G S G T D Y S L T I S N L E P E D I A T Y F C Q H H I K F P W T F G A G T K L E I K

Antigen Details
Antigen chainsP
Antigen typeprotein
Antigen namecytochrome b-c1 complex subunit rieske,mitochondrial
Antigen speciesSACCHAROMYCES CEREVISIAE
Antigen sequenceKSTYRTPNFDDVLKENNDADKGRSYAYFMVGAMGLLSSAGAKSTVETFISSMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEANSVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPAYEFDGDKVIVG

CDR Sequences (chothia definition)
CDRH1GYSITSGY
CDRH2SNVGD
CDRH3SEYYSVTGYAMDY
CDRL1RASQDINNFLN
CDRL2YTSRLHA
CDRL3QHHIKFPWT

Orientation Angles (from ABangle)
HL-62.88°
HC173.91°
HC2115.95°
LC1120.35°
LC280.25°
dc15.4Å
>   J/K
Fv Details
Heavy chainJ
Light chainK
Heavy subgroupIGHV3
Light subgroupIGKV10
SpeciesMUS MUSCULUS
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 101 102 103 104 105 106 107 108 109 110 111 112 113
E V K L Q E S G A G L V Q P S Q S L S L T C S V T G Y S I T S G Y Y W N W I R L F P G N K L E W V G Y I S N V G D N N Y N P S L K D R L S I T R D T S K N Q F F L K L N S V T T E D T A T Y Y C A R S E Y Y S V T G Y A M D Y W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I E L T Q T P V S L A A S L G D R V T I S C R A S Q D I N N F L N W Y Q Q K P D G T I K L L I Y Y T S R L H A G V P S R F S G S G S G T D Y S L T I S N L E P E D I A T Y F C Q H H I K F P W T F G A G T K L E I K

Antigen Details
Antigen chainsE
Antigen typeprotein
Antigen namecytochrome b-c1 complex subunit rieske,mitochondrial
Antigen speciesSACCHAROMYCES CEREVISIAE
Antigen sequenceKSTYRTPNFDDVLKENNDADKGRSYAYFMVGAMGLLSSAGAKSTVETFISSMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEANSVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPAYEFDGDKVIVG

CDR Sequences (chothia definition)
CDRH1GYSITSGY
CDRH2SNVGD
CDRH3SEYYSVTGYAMDY
CDRL1RASQDINNFLN
CDRL2YTSRLHA
CDRL3QHHIKFPWT

Orientation Angles (from ABangle)
HL-62.53°
HC173.9°
HC2115.7°
LC1118.67°
LC280.75°
dc15.49Å
>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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