Structure Viewer: 3iy7

>   Structure details

Variable Domains of the Computer Generated Model (Wam) of Fab F Fitted into the Cryoem Reconstruction of the Virus-Fab F complex

PDB3iy7
SpeciesRATTUS NORVEGICUS
MethodELECTRON MICROSCOPY
Resolution14Å
Number of Fvs1
In complexTrue
Light chain typeKappa
Has constant regionFalse
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>   Fv information

This PDB has 1 Fv(s).

>   B/A
Fv Details
Heavy chainB
Light chainA
Heavy subgroupIGHV2
Light subgroupIGKV22
SpeciesRATTUS NORVEGICUS
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 101 102 103 104 105 106 107 108 109 110 111 112
S G P G L V Q P S Q T L S L T C T V S G F S L T S Y G V S W V R Q P P G K G L E W I G T M W N D G D T D Y H S A L R S R L S I S R D S S K S Q V L L K M N S L Q T E D T A M Y F C A R S Q L P G Y N L R G W F V Y W G Q G T L V I V S

Light chain

3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 96 97 98 99 100 101 102 103 104 105 106 107
L M T Q I P S L L S A S V G D R V T L N C K A S H N I N K N L E W Y Q Q K L G E A P K L L I Y Y A N N L Q T G I S S R F S G S G S G T D Y T L T I S S L Q P E D V A T Y Y C Y Q Y N S G H T F G A G T K L E L K

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GFSLTSY
CDRH2WNDGD
CDRH3SQLPGYNLRGWFVY
CDRL1KASHNINKNLE
CDRL2YANNLQT
CDRL3YQYNSGHT

Orientation Angles (from ABangle)
HL-59.37°
HC170.81°
HC2118.42°
LC1118.55°
LC280.83°
dc15.96Å
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Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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