Structure Viewer: 4z9k

>   Structure details

Ricin a Chain Bound to Camelid Nanobody (Vhh2)(F5)

PDB4z9k
SpeciesVICUGNA PACOS
MethodX-RAY DIFFRACTION
Resolution1.5Å
Number of Fvs1
In complexTrue
Light chain type
Has constant regionFalse
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>   Fv information

This PDB has 1 Fv(s).

>   B/-
Fv Details
Heavy chainB
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesVICUGNA PACOS
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 101 102 103 104 105 106 107 108 109 110 111
V Q L V E S G G G L V Q P G G S L R L S C A A S G F T L D D Y A I G W F R Q V P G K E R E G V A C V K D G S T Y Y A D S V K G R F T I S R D N G A V Y L Q M N S L K P E D T A V Y Y C A S R P C F L G V P L I D F G S W G Q G T Q V T V

Antigen Details
Antigen chainsA
Antigen typeprotein
Antigen namericin
Antigen speciesRICINUS COMMUNIS
Antigen sequenceKQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAP

CDR Sequences (chothia definition)
CDRH1GFTLDDY
CDRH2KDGS
CDRH3RPCFLGVPLIDFGS

>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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