Synthetic Nanobody in complex with Mbp
| PDB | 5m13 |
| Species | SYNTHETIC CONSTRUCT |
| Method | X-RAY DIFFRACTION |
| Resolution | 1.372Å |
| Number of Fvs | 1 |
| In complex | True |
| Light chain type | |
| Has constant region | False |
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Display options: |
This PDB has 1 Fv(s).
| Fv Details | |
|---|---|
| Heavy chain | B |
| Light chain | |
| Heavy subgroup | IGHV1 |
| Light subgroup | |
| Species | SYNTHETIC CONSTRUCT |
| In complex? | True |
| scFv? | False |
| Has constant domain? | False |
| Numbered Sequences (chothia) |
|---|
Heavy chain
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| Q | V | Q | L | V | E | S | G | G | G | S | V | Q | A | G | G | S | L | R | L | S | C | V | A | S | G | D | I | K | Y | I | S | Y | L | G | W | F | R | Q | A | P | G | K | E | R | E | G | V | A | A | L | Y | T | S | T | G | R | T | Y | Y | A | D | S | V | K | G | R | F | T | V | S | L | D | N | A | K | N | T | V | Y | L | Q | M | N | S | L | K | P | E | D | T | A | L | Y | Y | C | A | A | A | E | W | G | S | Q | S | P | L | T | Q | W | F | Y | R | Y | W | G | Q | G | T | Q | V | T | V | S | A |
| Antigen Details | |
|---|---|
| Antigen chains | |
| Antigen type | |
| Antigen name | |
| Antigen species | SYNTHETIC CONSTRUCT |
| Antigen sequence | |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GDIKYIS |
| CDRH2 | YTSTGR |
| CDRH3 | AEWGSQSPLTQWFYRY |
Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]
SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]
Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]
