Structure Viewer: 5nml

>   Structure details

Nb36 Ser85Cys with Hg Bound

PDB5nml
SpeciesLAMA GLAMA
MethodX-RAY DIFFRACTION
Resolution2.5Å
Number of Fvs10
In complexTrue
Light chain type
Has constant regionFalse
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>   Fv information

This PDB has 10 Fv(s).

>   F/-
Fv Details
Heavy chainF
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   H/-
Fv Details
Heavy chainH
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   D/-
Fv Details
Heavy chainD
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   E/-
Fv Details
Heavy chainE
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   I/-
Fv Details
Heavy chainI
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   A/-
Fv Details
Heavy chainA
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   J/-
Fv Details
Heavy chainJ
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   B/-
Fv Details
Heavy chainB
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   C/-
Fv Details
Heavy chainC
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   G/-
Fv Details
Heavy chainG
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 101 102 103 104 105 106 107 108 109 110 111 112 113
V Q L V E S G G G L V Q A G G S L R L S C V V S G S A V S D Y A M G W Y R Q A P G K Q R E L V A A I Y N S G R T N Y V D S V K G R F T I S K D N A K K T V Y L Q M N C L K P E D T A D Y F C N L L G A T T M S N A V W G Q G T Q V T V S S

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSAVSDY
CDRH2YNSGR
CDRH3LGATTMSNAV

>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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