Structure Viewer: 6hdc

>   Structure details

Crystal Structure of the Potassium Channel Mttmem175 T38a Variant in complex with a Nanobody-Mbp Fusion Protein

PDB6hdc
SpeciesCHIMERIC ESCHERICHIA COLI (STRAIN K12)/LAMA GLAMA
MethodX-RAY DIFFRACTION
Resolution3.4Å
Number of Fvs1
In complexTrue
Light chain type
Has constant regionTrue
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>   Fv information

This PDB has 1 Fv(s).

>   A/-
Fv Details
Heavy chainA
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesCHIMERIC ESCHERICHIA COLI (STRAIN K12)/LAMA GLAMA
In complex?True
scFv?False
Has constant domain?True

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 101 102 103 104 105 106 107 108 109 110 111 112 113
Q R Q L V E S G G G L V Q P G G S L R L S C A A S G S I L Y F N R M G W Y R Q A P G K Q R E L V A A I T S G D S T N Y A D P V K G R F T I S R D N A K N T V Y L Q M N S L K P E D T A V Y Y C N A K E K G W S F S L Y D Y W G Q G T P V T V V K

Antigen Details
Antigen chains
Antigen type
Antigen name
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GSILYFN
CDRH2TSGDS
CDRH3KEKGWSFSLYDY

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Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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