Structure Viewer: 6z3k

> Structure details

Structure of Protective antibody 38-1-10a Fab

PDB	6z3k
Species	HOMO SAPIENS
Method	X-RAY DIFFRACTION
Resolution	2.7Å
Number of Fvs	9
In complex	False
Light chain type	Kappa
Has constant region	True

> Fv information

This PDB has 9 Fv(s).

Fv Details
Heavy chain	H
Light chain	L
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-57.5°
HC1	71.55°
HC2	119.78°
LC1	120.48°
LC2	84.04°
dc	15.97Å

Fv Details
Heavy chain	G
Light chain	I
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-54.45°
HC1	71.43°
HC2	119.53°
LC1	122.63°
LC2	85.63°
dc	16.08Å

Fv Details
Heavy chain	Q
Light chain	R
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-56.93°
HC1	71.83°
HC2	120.36°
LC1	120.83°
LC2	83.68°
dc	15.9Å

Fv Details
Heavy chain	A
Light chain	B
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-54.33°
HC1	71.79°
HC2	120.02°
LC1	121.35°
LC2	84.36°
dc	16.17Å

Fv Details
Heavy chain	M
Light chain	N
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-57.86°
HC1	72.25°
HC2	120.54°
LC1	120.33°
LC2	83.37°
dc	15.86Å

Fv Details
Heavy chain	C
Light chain	D
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-53.85°
HC1	71.91°
HC2	118.58°
LC1	123.07°
LC2	85.03°
dc	16.21Å

Fv Details
Heavy chain	J
Light chain	K
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-56.23°
HC1	72.0°
HC2	119.49°
LC1	121.55°
LC2	84.59°
dc	15.87Å

Fv Details
Heavy chain	E
Light chain	F
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-53.46°
HC1	71.94°
HC2	120.08°
LC1	122.96°
LC2	85.09°
dc	15.97Å

Fv Details
Heavy chain	O
Light chain	P
Heavy subgroup	IGHV4
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	31A	31B	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	L	Q	L	Q	E	S	G	P	G	L	V	K	P	S	E	T	L	S	L	T	C	T	V	S	G	G	S	I	S	S	S	S	Y	Y	W	G	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	S	I	Y	Y	S	G	S	T	Y	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	F	S	L	K	L	S	S	V	T	A	A	D	T	A	V	Y	Y	C	A	R	E	I	T	M	I	A	W	F	D	P	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	G	I	R	N	D	L	G	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	A	A	S	S	L	Q	S	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	F	A	T	Y	Y	C	L	Q	D	Y	N	Y	L	L	T	F	G	G	G	T	K	V	E	I	K

CDR Sequences (chothia definition)
CDRH1	GGSISSSSY
CDRH2	YYSGS
CDRH3	EITMIAWFDP
CDRL1	RASQGIRNDLG
CDRL2	AASSLQS
CDRL3	LQDYNYLLT

Orientation Angles (from ABangle)
HL	-58.7°
HC1	71.67°
HC2	120.05°
LC1	119.86°
LC2	83.98°
dc	15.95Å

Additional links and files for download: see help for more details.

Chothia-numbered structure	Download
IMGT-numbered structure	Download
Non-annotated structure from the PDB	Download
Summary file for this antibody	Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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