Structure Viewer: 7sjs

>   Structure details

Crystal Structure of Sars-Cov-2 Spike Stem Helix Peptide in complex with Neutralizing antibody Cc40.8

PDB7sjs
SpeciesHOMO SAPIENS
MethodX-RAY DIFFRACTION
Resolution1.612Å
Number of Fvs1
In complexTrue
Light chain typeLambda
Has constant regionTrue
>   Structure visualisation
Please note the WebGL plugin needs to be enabled to use PV Viewer.

Display options:














>   Fv information

This PDB has 1 Fv(s).

>   H/L
Fv Details
Heavy chainH
Light chainL
Heavy subgroupIGHV3
Light subgroupIGLV3
SpeciesHOMO SAPIENS
In complex?True
scFv?False
Has constant domain?True

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 101 102 103 104 105 106 107 108 109 110 111 112 113
E V Q L L E S G G G L V Q P G G S L R L S C A A S G F T F S S Y V M T W A R Q A P G K G L E W V S A I S G T G Y T Y Y A D S V K G R F T V S R D N S K N T L F L Q M S S L R A E D T A V Y Y C A I T M A P V V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 95A 95B 96 97 98 99 100 101 102 103 104 105 106 107
S Y E L T Q P P S V S V S P G Q T A R I T C S G D A L P K R Y A Y W Y Q Q K S G Q A P I L V I Y E D K K R P S G I P E R L S G S K S G T V A T L T I S G A Q V E D E A D Y Y C Y S T D S S G N H A V F G G G T Q L T V L

Antigen Details
Antigen chainsC
Antigen typepeptide
Antigen namestem helix peptide of spike protein s2'
Antigen speciesSEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS2
Antigen sequencePLQPELDSFKEELDKYFKNHTSPDV

CDR Sequences (chothia definition)
CDRH1GFTFSSY
CDRH2SGTGY
CDRH3TMAPVV
CDRL1SGDALPKRYAY
CDRL2EDKKRPS
CDRL3YSTDSSGNHAV

Orientation Angles (from ABangle)
HL-53.25°
HC171.69°
HC2123.84°
LC1116.58°
LC285.5°
dc16.15Å
>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

Our privacy policy