Structure Viewer: 8rmk

>   Structure details

Cryo-Em Structure of Human Calhm2 in complex with Synthetic Nanobody Sbc2

PDB8rmk
SpeciesSYNTHETIC CONSTRUCT
MethodELECTRON MICROSCOPY
Resolution3.07Å
Number of Fvs11
In complexTrue
Light chain typeNA
Has constant regionFalse
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>   Fv information

This PDB has 11 Fv(s).

>   L/-
Fv Details
Heavy chainL
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsB
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   M/-
Fv Details
Heavy chainM
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsC
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   N/-
Fv Details
Heavy chainN
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsD
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   O/-
Fv Details
Heavy chainO
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsE
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   P/-
Fv Details
Heavy chainP
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsF
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   Q/-
Fv Details
Heavy chainQ
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsG
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   R/-
Fv Details
Heavy chainR
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsH
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   S/-
Fv Details
Heavy chainS
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsI
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   T/-
Fv Details
Heavy chainT
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsJ
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   U/-
Fv Details
Heavy chainU
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsK
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   V/-
Fv Details
Heavy chainV
Light chain
Heavy subgroupIGHV1
Light subgroupNA
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L V E S G G G S V Q A G G S L R L S C A A S G N I R N I S Y L G W F R Q A P G K E R E G V A A L W T T Q G Q T Y Y A D S V K G R F T V S L D N A K N T V Y L Q M N S L K P E D T A L Y Y C A A A T S G Q Y N P L R G Y H Y N E Y W G Q G T Q V T V S A

Antigen Details
Antigen chainsA
Antigen typeprotein
Antigen namecalcium homeostasis modulator protein 2
Antigen speciesHOMO SAPIENS
Antigen sequenceMSAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPSALEVLFQ

CDR Sequences (chothia definition)
CDRH1GNIRNIS
CDRH2WTTQGQ
CDRH3ATSGQYNPLRGYHYNEY

>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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