SAbDab: The Structural Antibody Database

> About

Antibody- and Nanobody-derived therapeutics with known sequences, and their structural coverage in the PDB.
Use the 'Get all therapeutics' tab to get a list of all immunotherapeutics.
Search by name: Find a specific entry using its INN -mab or -fusp name.
Search by attribute: Find a subset of immunotherapeutics with particular attributes. Choose from format, target, highest clinical trial reached, development status, year INN proposed, or structural coverage (or any combination).
Search by sequence: Find therapeutics near to your query sequence over any Chothia-defined region of the heavy and/or light chain variable domain sequence.
For more help, see the About page.
If you believe we have missed a WHO-recognised therapeutic with a public sequence, please contact us at opig <~at~> stats.ox.ac.uk

> Get all immunotherapeutics

> Search for a specific therapeutic

> Search therapeutics by attribute

Therapeutic format:

Year INN Proposed:

Highest Clinical Trial:

Developmental Status:

Target:

Restrict to Known Structures:

> Search for therapeutics by sequence similarity

Heavy chain sequence:

load example

Light chain sequence:

load example

Max No. of Therapeutics to be returned:

Minimum sequence identity:

Region to consider:

> Downloads

Thera-SAbDab tracks all WHO-recognised Antibody- and Nanobody-derived therapeutics with released sequences.

Download all the therapeutic sequences we are currently tracking: xlsx / csv

Download all therapeutic sequences/structures including WHO PL121. These extra sequences will be pushed to Thera-SAbDab on my return from annual leave, at the end of September: xlsx / csv

Download a list of all tracked therapeutics without sequence data: xlsx / csv

If you believe we have missed a WHO-recognised therapeutic with a public sequence, please contact us at opig <~at~> stats.ox.ac.uk

Thera-SAbDab

(Therapeutic Structural Antibody Database)