Therapeutic | Benralizumab |
Target | IL5RA |
Heavy Chain | EVQLVQSGAEVKKPGASVKVSCKASGYTFTSYVIHWVRQRPGQGLAWMGYINPYNDGTKYNERFKGKVTITSDRSTSTVYMELSSLRSEDTAVYLCGREGIRYYGLLGDYWGQGTLVTVSS |
Light Chain | DIQMTQSPSSLSASVGDRVTITCGTSEDIINYLNWYQQKPGKAPKLLIYHTSRLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQGYTLPYTFGQGTKVEIK |
100% seqID Fv Structure | None |
99% seqID Fv Structure | None |
95-98% seqID Fv Structure | None |
Follow these links to our prediction tools:
Format | Whole mAb |
Isotype | G1 |
Highest Clinical Trial (June '19) | Approved |
Estimated Status (June '19) | Active |
Recorded Developmental Technology | POTELLIGENT Technology |
INN Year Proposed | 2009 |
INN Year Recommended | 2010 |
Companies Involved | AstraZeneca, Cincinnati Children's Hospital Medical Center, Kyowa Hakko, Kyowa Hakko Kirin, McMaster University, MedImmune, National Jewish Medical and Research Center, BioWa |
Conditions Approved | Asthma |
Conditions Active | Chronic obstructive pulmonary disease, Nasal polyps, Atopic dermatitis, Churg-Strauss syndrome, Hypereosinophilic syndrome, Rhinosinusitis, Eosinophilic gastroenteritis, Skin disorders |
Conditions Discontinued | na |
Notes |