Thera-SAbDab

EFUNGUMAB

> Structural Summary

Therapeutic	Efungumab
Target	Heat Shock Protein 90 Homolog
Heavy Chain	EVQLVESGAEVKKPGESLRISCKGSGCIISSYWISWVRQMPGKGLEWMGKIDPGDSYINYSPSFQGHVTISADKSINTAYLQWNSLKASDTAMYYCARGGRDFGDSFDYWGQGTLVTVSS
Light Chain	DVVMTQSPSFLSAFVGDRITITCRASSGISRYLAWYQQAPGKAPKLLIYAASTLQTGVPSRFSGSGSGTEFTLTINSLQPEDFATYYCQHLNSYPLTFGGGTKVDIK
100% seqID Fv Structure	None
99% seqID Fv Structure	None
95-98% seqID Fv Structure	None

There are currently no PDB structures close in sequence to this therapeutic Fv. Click here to build a model with ABodyBuilder.

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Format	scFv
Isotype	na
Highest Clinical Trial (June '19)	Phase-III
Estimated Status (June '19)	Discontinued
Recorded Developmental Technology	na
INN Year Proposed	2006
INN Year Recommended	2007
Companies Involved	NeuTec Pharma
Conditions Approved	na
Conditions Active	na
Conditions Discontinued	Breast cancer, Candidiasis
Notes

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]