TCR Details:

Item	Info
VB chain	E
VA chain	D
VB IMGT details	TRBV12/TRBJ2
VA IMGT details	TRAV12/TRAJ12
Species	human

Antigen Details:

Item	Info
Antigen Chain	C
Antigen Type	Peptide
Antigen Organism	HOMO SAPIENS
Antigen Sequence	RQFGPDFPTI
Antigen Length	10

MHC details:

Item	Info
MHC Chain	A | B
MHC Type	MH1
MHC Species	human
MHC IMGT details	HLA-A*0201

Numbered sequence

Chain type	Chain ID	FASTA/Annotation file	IMGT numbered sequence (Framework/CDR)
VB	E	FASTA file	B1 B2 B3 B4 B5 B6 B7 B8 D A G V I Q S P B9 B10 B11 B12 B13 B14 B15 B16 R H E V T E M G B17 B18 B19 B20 B21 B22 B23 B24 Q Q V T L R C K B25 B26 B27 B28 B29 B37 B38 B39 P I S G H D Y L B40 B41 B42 B43 B44 B45 B46 B47 F W Y R Q T M M B48 B49 B50 B51 B52 B53 B54 B55 R G L E L L I Y B56 B57 B58 B63 B64 B65 B66 B67 F N N N V P I D B68 B69 B70 B71 B72 B73 B74 B75 D S G M P E D R B76 B77 B78 B79 B80 B81 B83 B84 F S A K M P N A B85 B86 B87 B88 B89 B90 B91 B92 S F S T L K I Q B93 B94 B95 B96 B97 B98 B99 B100 P S E P R D S A B101 B102 B103 B104 B105 B106 B107 B108 V Y F C A S S L B109 B110 B111 B112A B112 B113 B114 B115 W E K L A K N I B116 B117 B118 B119 B120 B121 B122 B123 Q Y F G A G T R B124 B125 B126 B127 L S V L
VA	D	FASTA file	A3 A4 A5 A6 A7 A8 A9 A10 E V E Q D P G P A11 A12 A13 A14 A15 A16 A17 A18 L S V P E G A I A19 A20 A21 A22 A23 A24 A25 A26 V S L N C T Y S A27 A28 A29 A36 A37 A38 A39 A40 N S A F Q Y F M A41 A42 A43 A44 A45 A46 A47 A48 W Y R Q Y S R K A49 A50 A51 A52 A53 A54 A55 A56 G P E L L M Y T A57 A58 A63 A64 A65 A66 A67 A68 Y S S G N K E D A74 A75 A76 A77 A78 A79 A80 A81 G R F T A Q V D A82 A83 A84 A85 A86 A87 A88 A89 K S S K Y I S L A90 A91 A92 A93 A94 A95 A96 A97 F I R D S Q P S A98 A99 A100 A101 A102 A103 A104 A105 D S A T Y L C A A106 A107 A108 A109 A110 A113 A114 A115 M R G D S S Y K A116 A117 A118 A119 A120 A121 A122 A123 L I F G S G T R A124 A125 A126 A127 A128 L L V R P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLWEKLAKNIQY	None	14
CDRB2	FNNNVP	None	6
CDRB1	SGHDY	None	5
CDRA3	AMRGDSSYKLI	None	11
CDRA2	TYSSGN	A2-6-B	6
CDRA1	NSAFQY	None	6

Orientation and docking angles:

Angle	Value
BC2	111.82°
BC1	79.76°
BA	-60.18°
AC2	82.23°
AC1	122.29°
dc	15.88Å
Docking angle	45.15°

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
5c08_JI	111.51°	79.52°	-60.13°	81.85°	122.01°	15.86Å	0.6
5c0c_JI	111.80°	79.68°	-60.41°	81.66°	122.42°	15.89Å	0.6
5c07_JI	111.32°	79.91°	-60.76°	81.71°	122.19°	15.85Å	0.9
5c0c_ED	112.16°	79.79°	-60.27°	81.04°	122.31°	15.89Å	1.2
5c09_JI	111.34°	79.36°	-61.57°	81.44°	122.47°	15.87Å	1.7

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
4jkp_HL	113.93°	77.37°	-58.92°	82.11°	124.47°	15.16Å	4.1
3u7y_HL	113.61°	76.93°	-60.36°	81.15°	125.35°	15.13Å	4.7
5kve_HL	114.57°	75.61°	-60.03°	81.58°	122.90°	15.89Å	5.1
1cl7_HL	111.63°	74.67°	-60.00°	82.67°	121.69°	16.39Å	5.2
3cvh_QR	113.65°	77.38°	-59.58°	79.78°	118.82°	15.93Å	5.2

TCR Details:

Item	Info
VB chain	J
VA chain	I
VB IMGT details	TRBV12/TRBJ2
VA IMGT details	TRAV12/TRAJ12
Species	human

Antigen Details:

Item	Info
Antigen Chain	H
Antigen Type	Peptide
Antigen Organism	HOMO SAPIENS
Antigen Sequence	RQFGPDFPTI
Antigen Length	10

MHC details:

Item	Info
MHC Chain	F | G
MHC Type	MH1
MHC Species	human
MHC IMGT details	HLA-A*0201

Numbered sequence

Chain type	Chain ID	FASTA/Annotation file	IMGT numbered sequence (Framework/CDR)
VB	J	FASTA file	B1 B2 B3 B4 B5 B6 B7 B8 D A G V I Q S P B9 B10 B11 B12 B13 B14 B15 B16 R H E V T E M G B17 B18 B19 B20 B21 B22 B23 B24 Q Q V T L R C K B25 B26 B27 B28 B29 B37 B38 B39 P I S G H D Y L B40 B41 B42 B43 B44 B45 B46 B47 F W Y R Q T M M B48 B49 B50 B51 B52 B53 B54 B55 R G L E L L I Y B56 B57 B58 B63 B64 B65 B66 B67 F N N N V P I D B68 B69 B70 B71 B72 B73 B74 B75 D S G M P E D R B76 B77 B78 B79 B80 B81 B83 B84 F S A K M P N A B85 B86 B87 B88 B89 B90 B91 B92 S F S T L K I Q B93 B94 B95 B96 B97 B98 B99 B100 P S E P R D S A B101 B102 B103 B104 B105 B106 B107 B108 V Y F C A S S L B109 B110 B111 B112A B112 B113 B114 B115 W E K L A K N I B116 B117 B118 B119 B120 B121 B122 B123 Q Y F G A G T R B124 B125 B126 B127 L S V L
VA	I	FASTA file	A3 A4 A5 A6 A7 A8 A9 A10 E V E Q D P G P A11 A12 A13 A14 A15 A16 A17 A18 L S V P E G A I A19 A20 A21 A22 A23 A24 A25 A26 V S L N C T Y S A27 A28 A29 A36 A37 A38 A39 A40 N S A F Q Y F M A41 A42 A43 A44 A45 A46 A47 A48 W Y R Q Y S R K A49 A50 A51 A52 A53 A54 A55 A56 G P E L L M Y T A57 A58 A63 A64 A65 A66 A67 A68 Y S S G N K E D A74 A75 A76 A77 A78 A79 A80 A81 G R F T A Q V D A82 A83 A84 A85 A86 A87 A88 A89 K S S K Y I S L A90 A91 A92 A93 A94 A95 A96 A97 F I R D S Q P S A98 A99 A100 A101 A102 A103 A104 A105 D S A T Y L C A A106 A107 A108 A109 A110 A113 A114 A115 M R G D S S Y K A116 A117 A118 A119 A120 A121 A122 A123 L I F G S G T R A124 A125 A126 A127 A128 L L V R P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLWEKLAKNIQY	None	14
CDRB2	FNNNVP	None	6
CDRB1	SGHDY	None	5
CDRA3	AMRGDSSYKLI	None	11
CDRA2	TYSSGN	A2-6-B	6
CDRA1	NSAFQY	None	6

Orientation and docking angles:

Angle	Value
BC2	112.28°
BC1	80.10°
BA	-60.73°
AC2	80.73°
AC1	121.94°
dc	15.83Å
Docking angle	43.90°

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
5c07_ED	112.10°	80.10°	-60.76°	80.35°	122.08°	15.77Å	0.4
5c0c_ED	112.16°	79.79°	-60.27°	81.04°	122.31°	15.89Å	0.7
5c08_ED	111.93°	80.00°	-60.13°	80.39°	121.87°	15.78Å	0.8
5c0c_JI	111.80°	79.68°	-60.41°	81.66°	122.42°	15.89Å	1.3
5c07_JI	111.32°	79.91°	-60.76°	81.71°	122.19°	15.85Å	1.4

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
3cvh_QR	113.65°	77.38°	-59.58°	79.78°	118.82°	15.93Å	4.6
4jkp_HL	113.93°	77.37°	-58.92°	82.11°	124.47°	15.16Å	4.7
3u7y_HL	113.61°	76.93°	-60.36°	81.15°	125.35°	15.13Å	4.9
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	4.9
3ncy_PS	112.64°	76.63°	-61.62°	81.39°	118.27°	15.77Å	5.2