| Reference title | CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches |
| Reference authors | Argiriadi,M.A.;Benatuil,L.;Dubrovska,I. et al. |
| Reference URL | https://opig.stats.ox.ac.uk/webapps/newsabdab/sabdab/structureviewer/?pdb=6pe8 |
| Heavy chain | EVQLVESGGGLVKPGGSLRLSCAASGFTFSDYGMNWVRQAPGKGLEWIAYISSGRGNIYYADTVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARSWGYFDVWGQGTTVTVSS |
| Light chain | DIVMTQSPDSLAVSLGERATINCKSSQSLLNRGNQKNYLTWFQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQNDYTYPLTFGQGTKLEIK |
| Heavy chain definition | Crystal Structure Of Cd40/Abbv-323 Fab Complex |
| Light chain definition | Crystal Structure Of Cd40/Abbv-323 Fab Complex |
| Organism | homo sapiens |
| Targets mentioned | TNFRSF5; p50; Bp50; CD40 |
| Update date | 20-JUN-2019 |
Brennan Abanades et al. “The Patent and Literature Antibody Database (PLAbDab):
an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures”. In: Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D545-D551 [ link]
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Header image credit: David Goodsell
