| Reference title | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab |
| Reference authors | Sun,J.;Zhang,X.;Xue,L. et al. |
| Reference URL | https://opig.stats.ox.ac.uk/webapps/newsabdab/sabdab/structureviewer/?pdb=8jeo |
| Heavy chain | EVQLQQSGPGLVKPSQTLSLTCAISGDSVSSNSAAWNWIRQSPSRGLEWLGKTYYRFKWYSDYAVSVKGRITINPDTSKNQFSLQLNSVTPEDTAVFYCTRESTTYDLLAGPFDYWGQGTLVTVSS |
| Light chain | DIVMTQSPDSLAVSLGERATINCKSSQTVLYSSNNKKYLAWYQQKPGQPPNLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPFTFGPGTKVEIK |
| Heavy chain definition | Crystal Structure Of Tigit In Complexed With Tiragolumab |
| Light chain definition | Crystal Structure Of Tigit In Complexed With Tiragolumab |
| Organism | homo sapiens |
| Targets mentioned | VSTM3; DKFZp667A205; VSIG9; FLJ39873; TIGIT |
| Update date | 28-FEB-2024 |
Brennan Abanades et al. “The Patent and Literature Antibody Database (PLAbDab):
an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures”. In: Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D545-D551 [ link]
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Header image credit: David Goodsell
