Structure Viewer: 5ip4

>   Structure details

X-Ray Structure of the C-Terminal Domain of Human Doublecortin

PDB5ip4
SpeciesLAMA GLAMA
MethodX-RAY DIFFRACTION
Resolution1.81Å
Number of Fvs2
In complexTrue
Light chain type
Has constant regionFalse
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>   Fv information

This PDB has 2 Fv(s).

>   A/-
Fv Details
Heavy chainA
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G G G L V Q A G G S L R L S C T A S V N I I G G N H W A W Y R Q A P G Q Q R D L V A S L S R Y N A N Y A D S V K G R F T I S R D N A K N A A Y L Q M N S L K P E D T A I Y F C A L E N Y Y W G Q G T Q V T V S S

Antigen Details
Antigen chainsE
Antigen typeprotein
Antigen nameneuronal migration protein doublecortin
Antigen speciesHOMO SAPIENS
Antigen sequenceARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYA

CDR Sequences (chothia definition)
CDRH1VNIIGGN
CDRH2SRYN
CDRH3ENYY

>   B/-
Fv Details
Heavy chainB
Light chain
Heavy subgroupIGHV1
Light subgroup
SpeciesLAMA GLAMA
In complex?True
scFv?False
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G G G L V Q A G G S L R L S C T A S V N I I G G N H W A W Y R Q A P G Q Q R D L V A S L S R Y N A N Y A D S V K G R F T I S R D N A K N A A Y L Q M N S L K P E D T A I Y F C A L E N Y Y W G Q G T Q V T V S S

Antigen Details
Antigen chainsD
Antigen typeprotein
Antigen nameneuronal migration protein doublecortin
Antigen speciesHOMO SAPIENS
Antigen sequenceARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYA

CDR Sequences (chothia definition)
CDRH1VNIIGGN
CDRH2SRYN
CDRH3ENYY

>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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