Structure Viewer: 5mu0

> Structure details

acc1 Fab Fragment in complex with Citrullinated C1 Epitope of Cii (Ia03)

PDB	5mu0
Species	MUS MUSCULUS
Method	X-RAY DIFFRACTION
Resolution	2.7Å
Number of Fvs	8
In complex	True
Light chain type	Kappa
Has constant region	True

> Fv information

This PDB has 8 Fv(s).

Fv Details
Heavy chain	A
Light chain	B
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	Q
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-61.0°
HC1	72.21°
HC2	117.8°
LC1	116.07°
LC2	85.3°
dc	16.3Å

Fv Details
Heavy chain	M
Light chain	N
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	W
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-60.89°
HC1	71.82°
HC2	116.9°
LC1	117.52°
LC2	84.78°
dc	16.03Å

Fv Details
Heavy chain	I
Light chain	J
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	U
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-61.52°
HC1	71.74°
HC2	116.93°
LC1	116.56°
LC2	84.42°
dc	16.41Å

Fv Details
Heavy chain	G
Light chain	H
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	T
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-60.93°
HC1	72.18°
HC2	117.72°
LC1	117.59°
LC2	84.32°
dc	16.22Å

Fv Details
Heavy chain	O
Light chain	P
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	X
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-63.47°
HC1	72.12°
HC2	117.6°
LC1	117.96°
LC2	82.84°
dc	16.59Å

Fv Details
Heavy chain	C
Light chain	D
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	R
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-61.24°
HC1	70.94°
HC2	116.87°
LC1	117.54°
LC2	85.39°
dc	16.32Å

Fv Details
Heavy chain	E
Light chain	F
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	S
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-63.57°
HC1	71.37°
HC2	116.96°
LC1	115.92°
LC2	83.61°
dc	16.37Å

Fv Details
Heavy chain	K
Light chain	L
Heavy subgroup	IGHV6
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	K	L	E	E	S	G	G	G	L	V	Q	P	G	G	S	M	K	L	S	C	A	A	S	G	F	T	F	S	D	A	W	M	D	W	V	R	Q	S	P	E	K	G	L	E	W	V	A	E	I	R	N	K	V	N	N	H	A	T	N	Y	A	E	S	V	K	G	R	F	T	I	S	R	D	D	S	R	S	V	V	Y	L	Q	M	N	N	L	K	P	E	D	T	G	I	Y	Y	C	T	G	L	T	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	30B	30C	30D	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	Y	G	I	S	S	M	N	W	F	Q	Q	K	A	G	Q	P	P	K	F	L	I	Y	A	A	S	K	Q	G	S	G	V	P	A	R	F	S	G	S	G	S	G	T	D	F	S	L	I	I	H	P	V	E	E	D	D	T	A	V	Y	F	C	Q	Q	S	K	G	V	P	Y	T	F	G	G	G	T	K	L	E	I	K

Antigen Details
Antigen chains	V
Antigen type	peptide
Antigen name	ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii
Antigen species	MUS MUSCULUS
Antigen sequence	GPPGARGLTGRPGDAGPP

CDR Sequences (chothia definition)
CDRH1	GFTFSDA
CDRH2	RNKVNNHA
CDRH3	LTFDY
CDRL1	RASESVDNYGISSMN
CDRL2	AASKQGS
CDRL3	QQSKGVPYT

Orientation Angles (from ABangle)
HL	-62.87°
HC1	71.99°
HC2	118.25°
LC1	116.46°
LC2	82.61°
dc	16.36Å

Additional links and files for download: see help for more details.

Chothia-numbered structure	Download
IMGT-numbered structure	Download
Non-annotated structure from the PDB	Download
Summary file for this antibody	Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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